id	sid	tid	token	lemma	pos
aji-178	1	1	_	_	PUNCT
aji-178	2	1	_	_	PUNCT
aji-178	3	1	_	_	PUNCT
aji-178	4	1	_	_	PUNCT
aji-178	5	1	_	_	PUNCT
aji-178	6	1	_	_	PUNCT
aji-178	7	1	_	_	PUNCT
aji-178	8	1	_	_	PUNCT
aji-178	9	1	_	_	PUNCT
aji-178	10	1	_	_	PUNCT
aji-178	11	1	_	_	PUNCT
aji-178	12	1	_	_	PUNCT
aji-178	13	1	_	_	PUNCT
aji-178	14	1	_	_	PUNCT
aji-178	15	1	_	_	PUNCT
aji-178	16	1	_	_	PUNCT
aji-178	17	1	_	_	PUNCT
aji-178	18	1	_	_	PUNCT
aji-178	19	1	_	_	PUNCT
aji-178	20	1	_	_	PUNCT
aji-178	21	1	_	_	PUNCT
aji-178	22	1	_	_	PUNCT
aji-178	23	1	_	_	PUNCT
aji-178	24	1	_	_	PUNCT
aji-178	25	1	_	_	PUNCT
aji-178	26	1	_	_	PUNCT
aji-178	27	1	_	_	PUNCT
aji-178	28	1	_	_	PUNCT
aji-178	29	1	_	_	PUNCT
aji-178	30	1	_	_	PUNCT
aji-178	31	1	_	_	PUNCT
aji-178	32	1	_	_	PUNCT
aji-178	33	1	_	_	PUNCT
aji-178	34	1	_	_	PUNCT
aji-178	35	1	_	_	PUNCT
aji-178	36	1	_	_	PUNCT
aji-178	37	1	_	_	PUNCT
aji-178	38	1	_	_	PUNCT
aji-178	39	1	_	_	PUNCT
aji-178	40	1	_	_	PUNCT
aji-178	41	1	_	_	PUNCT
aji-178	42	1	_	_	PUNCT
aji-178	43	1	_	_	PUNCT
aji-178	44	1	_	_	PUNCT
aji-178	45	1	_	_	PUNCT
aji-178	46	1	_	_	PUNCT
aji-178	47	1	_	_	PUNCT
aji-178	48	1	_	_	PUNCT
aji-178	49	1	_	_	PUNCT
aji-178	50	1	_	_	PUNCT
aji-178	51	1	_	_	PUNCT
aji-178	52	1	_	_	PUNCT
aji-178	53	1	_	_	PUNCT
aji-178	54	1	_	_	PUNCT
aji-178	55	1	_	_	PUNCT
aji-178	56	1	_	_	PUNCT
aji-178	57	1	_	_	PUNCT
aji-178	58	1	_	_	PUNCT
aji-178	59	1	_	_	PUNCT
aji-178	60	1	_	_	PUNCT
aji-178	61	1	_	_	PUNCT
aji-178	62	1	_	_	PUNCT
aji-178	63	1	_	_	PUNCT
aji-178	64	1	_	_	PUNCT
aji-178	65	1	_	_	PUNCT
aji-178	66	1	_	_	PUNCT
aji-178	67	1	_	_	PUNCT
aji-178	68	1	_	_	PUNCT
aji-178	69	1	_	_	PUNCT
aji-178	70	1	_	_	PUNCT
aji-178	71	1	_	_	PUNCT
aji-178	72	1	_	_	PUNCT
aji-178	73	1	_	_	PUNCT
aji-178	74	1	_	_	PUNCT
aji-178	75	1	_	_	PUNCT
aji-178	76	1	_	_	PUNCT
aji-178	77	1	_	_	PUNCT
aji-178	78	1	_	_	PUNCT
aji-178	79	1	_	_	PUNCT
aji-178	80	1	_	_	PUNCT
aji-178	81	1	_	_	PUNCT
aji-178	82	1	_	_	PUNCT
aji-178	83	1	_	_	PUNCT
aji-178	84	1	_	_	PUNCT
aji-178	85	1	_	_	PUNCT
aji-178	86	1	_	_	PUNCT
aji-178	87	1	_	_	PUNCT
aji-178	88	1	_	_	PUNCT
aji-178	89	1	_	_	PUNCT
aji-178	90	1	_	_	PUNCT
aji-178	91	1	_	_	PUNCT
aji-178	92	1	_	_	PUNCT
aji-178	93	1	_	_	PUNCT
aji-178	94	1	_	_	PUNCT
aji-178	95	1	_	_	PUNCT
aji-178	96	1	_	_	PUNCT
aji-178	97	1	_	_	PUNCT
aji-178	98	1	_	_	PUNCT
aji-178	99	1	_	_	PUNCT
aji-178	100	1	_	_	PUNCT
aji-178	101	1	_	_	PUNCT
aji-178	102	1	*	*	PUNCT
aji-178	102	2	corresponding	correspond	VERB
aji-178	102	3	author	author	NOUN
aji-178	102	4	:	:	PUNCT
aji-178	102	5	e	e	NOUN
aji-178	102	6	-	-	NOUN
aji-178	102	7	mail	mail	NOUN
aji-178	102	8	:	:	PUNCT
aji-178	102	9	naseemar8@gmail.com	naseemar8@gmail.com	NUM
aji-178	102	10	;	;	PUNCT
aji-178	102	11	cite	cite	VERB
aji-178	102	12	as	as	ADP
aji-178	102	13	:	:	PUNCT
aji-178	102	14	naseema	naseema	NOUN
aji-178	102	15	.	.	PUNCT
aji-178	103	1	r.	r.	PROPN
aji-178	103	2	2025	2025	NUM
aji-178	103	3	.	.	PUNCT
aji-178	104	1	“	"	PUNCT
aji-178	104	2	an	an	DET
aji-178	104	3	immunocomputing	immunocomputing	NOUN
aji-178	104	4	approach	approach	NOUN
aji-178	104	5	to	to	ADP
aji-178	104	6	the	the	DET
aji-178	104	7	development	development	NOUN
aji-178	104	8	of	of	ADP
aji-178	104	9	multiepitope	multiepitope	NOUN
aji-178	104	10	vaccine	vaccine	NOUN
aji-178	104	11	against	against	ADP
aji-178	104	12	mycobacterium	mycobacterium	NOUN
aji-178	104	13	tuberculosis	tuberculosis	NOUN
aji-178	104	14	”	"	PUNCT
aji-178	104	15	.	.	PUNCT
aji-178	105	1	asian	asian	ADJ
aji-178	105	2	journal	journal	NOUN
aji-178	105	3	of	of	ADP
aji-178	105	4	immunology	immunology	NOUN
aji-178	105	5	8	8	NUM
aji-178	105	6	(	(	PUNCT
aji-178	105	7	1):269–284	1):269–284	NOUN
aji-178	105	8	.	.	PUNCT
aji-178	106	1	https://doi.org/10.9734/aji/2025/v8i1178	https://doi.org/10.9734/aji/2025/v8i1178	PROPN
aji-178	106	2	.	.	PUNCT
aji-178	107	1	asian	asian	ADJ
aji-178	107	2	journal	journal	PROPN
aji-178	107	3	of	of	ADP
aji-178	107	4	immunology	immunology	NOUN
aji-178	107	5	volume	volume	NOUN
aji-178	107	6	8	8	NUM
aji-178	107	7	,	,	PUNCT
aji-178	107	8	issue	issue	NOUN
aji-178	107	9	1	1	NUM
aji-178	107	10	,	,	PUNCT
aji-178	107	11	page	page	NOUN
aji-178	107	12	269	269	NUM
aji-178	107	13	-	-	SYM
aji-178	107	14	284	284	NUM
aji-178	107	15	,	,	PUNCT
aji-178	107	16	2025	2025	NUM
aji-178	107	17	;	;	PUNCT
aji-178	107	18	article	article	NOUN
aji-178	107	19	no.aji.147582	no.aji.147582	VERB
aji-178	107	20	an	an	DET
aji-178	107	21	immunocomputing	immunocompute	VERB
aji-178	107	22	approach	approach	NOUN
aji-178	107	23	to	to	ADP
aji-178	107	24	the	the	DET
aji-178	107	25	development	development	NOUN
aji-178	107	26	of	of	ADP
aji-178	107	27	multiepitope	multiepitope	NOUN
aji-178	107	28	vaccine	vaccine	NOUN
aji-178	107	29	against	against	ADP
aji-178	107	30	mycobacterium	mycobacterium	NOUN
aji-178	107	31	tuberculosis	tuberculosis	NOUN
aji-178	107	32	naseema	naseema	NOUN
aji-178	107	33	.	.	PUNCT
aji-178	108	1	r	r	NOUN
aji-178	108	2	a	a	PROPN
aji-178	108	3	*	*	X
aji-178	108	4	a	a	DET
aji-178	108	5	department	department	NOUN
aji-178	108	6	of	of	ADP
aji-178	108	7	biotechnology	biotechnology	NOUN
aji-178	108	8	,	,	PUNCT
aji-178	108	9	mepco	mepco	PROPN
aji-178	108	10	schlenk	schlenk	PROPN
aji-178	108	11	engineering	engineering	PROPN
aji-178	108	12	college	college	PROPN
aji-178	108	13	,	,	PUNCT
aji-178	108	14	sivakasi	sivakasi	NOUN
aji-178	108	15	,	,	PUNCT
aji-178	108	16	tamil	tamil	PROPN
aji-178	108	17	nadu	nadu	PROPN
aji-178	108	18	,	,	PUNCT
aji-178	108	19	india	india	PROPN
aji-178	108	20	.	.	PUNCT
aji-178	109	1	author	author	PROPN
aji-178	109	2	’s	’s	PART
aji-178	109	3	contribution	contribution	NOUN
aji-178	109	4	the	the	DET
aji-178	109	5	sole	sole	ADJ
aji-178	109	6	author	author	NOUN
aji-178	109	7	designed	design	VERB
aji-178	109	8	,	,	PUNCT
aji-178	109	9	analyzed	analyze	VERB
aji-178	109	10	,	,	PUNCT
aji-178	109	11	interpreted	interpret	VERB
aji-178	109	12	and	and	CCONJ
aji-178	109	13	prepared	prepare	VERB
aji-178	109	14	the	the	DET
aji-178	109	15	manuscript	manuscript	NOUN
aji-178	109	16	.	.	PUNCT
aji-178	110	1	article	article	NOUN
aji-178	110	2	information	information	PROPN
aji-178	110	3	doi	doi	PROPN
aji-178	110	4	:	:	PUNCT
aji-178	110	5	https://doi.org/10.9734/aji/2025/v8i1178	https://doi.org/10.9734/aji/2025/v8i1178	ADV
aji-178	110	6	open	open	ADJ
aji-178	110	7	peer	peer	NOUN
aji-178	110	8	review	review	NOUN
aji-178	110	9	history	history	NOUN
aji-178	110	10	:	:	PUNCT
aji-178	110	11	this	this	DET
aji-178	110	12	journal	journal	NOUN
aji-178	110	13	follows	follow	VERB
aji-178	110	14	the	the	DET
aji-178	110	15	advanced	advance	VERB
aji-178	110	16	open	open	ADJ
aji-178	110	17	peer	peer	NOUN
aji-178	110	18	review	review	NOUN
aji-178	110	19	policy	policy	NOUN
aji-178	110	20	.	.	PUNCT
aji-178	111	1	identity	identity	NOUN
aji-178	111	2	of	of	ADP
aji-178	111	3	the	the	DET
aji-178	111	4	reviewers	reviewer	NOUN
aji-178	111	5	,	,	PUNCT
aji-178	111	6	editor(s	editor(s	NOUN
aji-178	111	7	)	)	PUNCT
aji-178	111	8	and	and	CCONJ
aji-178	111	9	additional	additional	ADJ
aji-178	111	10	reviewers	reviewer	NOUN
aji-178	111	11	,	,	PUNCT
aji-178	111	12	peer	peer	NOUN
aji-178	111	13	review	review	NOUN
aji-178	111	14	comments	comment	NOUN
aji-178	111	15	,	,	PUNCT
aji-178	111	16	different	different	ADJ
aji-178	111	17	versions	version	NOUN
aji-178	111	18	of	of	ADP
aji-178	111	19	the	the	DET
aji-178	111	20	manuscript	manuscript	NOUN
aji-178	111	21	,	,	PUNCT
aji-178	111	22	comments	comment	NOUN
aji-178	111	23	of	of	ADP
aji-178	111	24	the	the	DET
aji-178	111	25	editors	editor	NOUN
aji-178	111	26	,	,	PUNCT
aji-178	111	27	etc	etc	X
aji-178	111	28	are	be	AUX
aji-178	111	29	available	available	ADJ
aji-178	111	30	here	here	ADV
aji-178	111	31	:	:	PUNCT
aji-178	111	32	https://pr.sdiarticle5.com/review-history/147582	https://pr.sdiarticle5.com/review-history/147582	NOUN
aji-178	111	33	received	receive	VERB
aji-178	111	34	:	:	PUNCT
aji-178	111	35	17/09/2025	17/09/2025	NUM
aji-178	111	36	published	publish	VERB
aji-178	111	37	:	:	PUNCT
aji-178	111	38	24/11/2025	24/11/2025	NUM
aji-178	111	39	abstract	abstract	ADJ
aji-178	111	40	tuberculosis	tuberculosis	NOUN
aji-178	111	41	(	(	PUNCT
aji-178	111	42	tb	tb	NOUN
aji-178	111	43	)	)	PUNCT
aji-178	111	44	is	be	AUX
aji-178	111	45	the	the	DET
aji-178	111	46	second	second	ADJ
aji-178	111	47	most	most	ADV
aji-178	111	48	deadly	deadly	ADJ
aji-178	111	49	airborne	airborne	ADJ
aji-178	111	50	infectious	infectious	ADJ
aji-178	111	51	disease	disease	NOUN
aji-178	111	52	caused	cause	VERB
aji-178	111	53	by	by	ADP
aji-178	111	54	mycobacterium	mycobacterium	NOUN
aji-178	111	55	tuberculosis	tuberculosis	NOUN
aji-178	111	56	,	,	PUNCT
aji-178	111	57	posing	pose	VERB
aji-178	111	58	a	a	DET
aji-178	111	59	major	major	ADJ
aji-178	111	60	global	global	ADJ
aji-178	111	61	health	health	NOUN
aji-178	111	62	risk	risk	NOUN
aji-178	111	63	dw	dw	PROPN
aji-178	111	64	.	.	PUNCT
aji-178	112	1	nearly	nearly	ADV
aji-178	112	2	one	one	NUM
aji-178	112	3	-	-	PUNCT
aji-178	112	4	third	third	NOUN
aji-178	112	5	of	of	ADP
aji-178	112	6	the	the	DET
aji-178	112	7	world	world	NOUN
aji-178	112	8	’s	’s	PART
aji-178	112	9	population	population	NOUN
aji-178	112	10	is	be	AUX
aji-178	112	11	infected	infect	VERB
aji-178	112	12	,	,	PUNCT
aji-178	112	13	with	with	ADP
aji-178	112	14	low	low	ADJ
aji-178	112	15	-	-	PUNCT
aji-178	112	16	income	income	NOUN
aji-178	112	17	countries	country	NOUN
aji-178	112	18	most	most	ADV
aji-178	112	19	affected	affected	ADJ
aji-178	112	20	due	due	ADJ
aji-178	112	21	to	to	ADP
aji-178	112	22	limited	limited	ADJ
aji-178	112	23	access	access	NOUN
aji-178	112	24	to	to	ADP
aji-178	112	25	diagnostics	diagnostic	NOUN
aji-178	112	26	and	and	CCONJ
aji-178	112	27	treatments	treatment	NOUN
aji-178	112	28	.	.	PUNCT
aji-178	113	1	although	although	SCONJ
aji-178	113	2	the	the	DET
aji-178	113	3	bacillus	bacillus	NOUN
aji-178	113	4	calmette	calmette	NOUN
aji-178	113	5	–	–	PUNCT
aji-178	113	6	guérin	guérin	PROPN
aji-178	113	7	(	(	PUNCT
aji-178	113	8	bcg	bcg	PROPN
aji-178	113	9	)	)	PUNCT
aji-178	113	10	vaccine	vaccine	NOUN
aji-178	113	11	offers	offer	VERB
aji-178	113	12	protection	protection	NOUN
aji-178	113	13	in	in	ADP
aji-178	113	14	infancy	infancy	NOUN
aji-178	113	15	,	,	PUNCT
aji-178	113	16	its	its	PRON
aji-178	113	17	reduced	reduce	VERB
aji-178	113	18	efficacy	efficacy	NOUN
aji-178	113	19	beyond	beyond	ADP
aji-178	113	20	20	20	NUM
aji-178	113	21	years	year	NOUN
aji-178	113	22	limits	limit	NOUN
aji-178	113	23	long	long	ADJ
aji-178	113	24	-	-	PUNCT
aji-178	113	25	term	term	NOUN
aji-178	113	26	tb	tb	ADP
aji-178	113	27	control	control	NOUN
aji-178	113	28	.	.	PUNCT
aji-178	114	1	this	this	DET
aji-178	114	2	study	study	NOUN
aji-178	114	3	focuses	focus	VERB
aji-178	114	4	on	on	ADP
aji-178	114	5	drafting	draft	VERB
aji-178	114	6	a	a	DET
aji-178	114	7	multi	multi	ADJ
aji-178	114	8	-	-	ADJ
aji-178	114	9	epitope	epitope	ADJ
aji-178	114	10	peptide	peptide	NOUN
aji-178	114	11	-	-	PUNCT
aji-178	114	12	based	base	VERB
aji-178	114	13	vaccine	vaccine	NOUN
aji-178	114	14	against	against	ADP
aji-178	114	15	tb	tb	NOUN
aji-178	114	16	using	use	VERB
aji-178	114	17	immune	immune	NOUN
aji-178	114	18	-	-	PUNCT
aji-178	114	19	informatics	informatic	NOUN
aji-178	114	20	approaches	approach	NOUN
aji-178	114	21	.	.	PUNCT
aji-178	115	1	ten	ten	NUM
aji-178	115	2	m.	m.	NOUN
aji-178	115	3	tuberculosis	tuberculosis	NOUN
aji-178	115	4	-	-	PUNCT
aji-178	115	5	specific	specific	ADJ
aji-178	115	6	antigenic	antigenic	ADJ
aji-178	115	7	proteins	protein	NOUN
aji-178	115	8	(	(	PUNCT
aji-178	115	9	ppe39	ppe39	NOUN
aji-178	115	10	,	,	PUNCT
aji-178	115	11	ppe68	ppe68	NOUN
aji-178	115	12	,	,	PUNCT
aji-178	115	13	rv0310c	rv0310c	PROPN
aji-178	115	14	,	,	PUNCT
aji-178	115	15	pe_pgrs35	pe_pgrs35	PROPN
aji-178	115	16	,	,	PUNCT
aji-178	115	17	pe_pgrs31	pe_pgrs31	NOUN
aji-178	115	18	,	,	PUNCT
aji-178	115	19	cfp10	cfp10	NOUN
aji-178	115	20	,	,	PUNCT
aji-178	115	21	rv1975	rv1975	PROPN
aji-178	115	22	,	,	PUNCT
aji-178	115	23	lpqg	lpqg	NOUN
aji-178	115	24	,	,	PUNCT
aji-178	115	25	esxv	esxv	NOUN
aji-178	115	26	,	,	PUNCT
aji-178	115	27	and	and	CCONJ
aji-178	115	28	espj	espj	NOUN
aji-178	115	29	)	)	PUNCT
aji-178	115	30	were	be	AUX
aji-178	115	31	analyzed	analyze	VERB
aji-178	115	32	to	to	PART
aji-178	115	33	identify	identify	VERB
aji-178	115	34	potent	potent	ADJ
aji-178	115	35	immunogenic	immunogenic	ADJ
aji-178	115	36	regions	region	NOUN
aji-178	115	37	.	.	PUNCT
aji-178	116	1	five	five	NUM
aji-178	116	2	cytotoxic	cytotoxic	ADJ
aji-178	116	3	t	t	NOUN
aji-178	116	4	lymphocyte	lymphocyte	NOUN
aji-178	116	5	(	(	PUNCT
aji-178	116	6	ctl	ctl	PROPN
aji-178	116	7	)	)	PUNCT
aji-178	116	8	epitopes	epitope	NOUN
aji-178	116	9	,	,	PUNCT
aji-178	116	10	five	five	NUM
aji-178	116	11	helper	helper	NOUN
aji-178	116	12	t	t	NOUN
aji-178	116	13	cell	cell	NOUN
aji-178	116	14	(	(	PUNCT
aji-178	116	15	htl	htl	PROPN
aji-178	116	16	)	)	PUNCT
aji-178	116	17	epitopes	epitope	NOUN
aji-178	116	18	,	,	PUNCT
aji-178	116	19	and	and	CCONJ
aji-178	116	20	several	several	ADJ
aji-178	116	21	b	b	NOUN
aji-178	116	22	-	-	PUNCT
aji-178	116	23	cell	cell	NOUN
aji-178	116	24	epitopes	epitope	NOUN
aji-178	116	25	are	be	AUX
aji-178	116	26	proficient	proficient	ADJ
aji-178	116	27	of	of	ADP
aji-178	116	28	causing	cause	VERB
aji-178	116	29	strong	strong	ADJ
aji-178	116	30	immune	immune	ADJ
aji-178	116	31	responses	response	NOUN
aji-178	116	32	,	,	PUNCT
aji-178	116	33	including	include	VERB
aji-178	116	34	interferon	interferon	ADJ
aji-178	116	35	-	-	PUNCT
aji-178	116	36	γ	γ	X
aji-178	116	37	(	(	PUNCT
aji-178	116	38	ifn	ifn	PROPN
aji-178	116	39	-	-	PUNCT
aji-178	116	40	γ	γ	NOUN
aji-178	116	41	)	)	PUNCT
aji-178	116	42	production	production	NOUN
aji-178	116	43	,	,	PUNCT
aji-178	116	44	were	be	AUX
aji-178	116	45	selected	select	VERB
aji-178	116	46	.	.	PUNCT
aji-178	117	1	a	a	DET
aji-178	117	2	total	total	NOUN
aji-178	117	3	of	of	ADP
aji-178	117	4	27	27	NUM
aji-178	117	5	epitopes	epitope	NOUN
aji-178	117	6	were	be	AUX
aji-178	117	7	linked	link	VERB
aji-178	117	8	using	use	VERB
aji-178	117	9	aay	aay	PROPN
aji-178	117	10	,	,	PUNCT
aji-178	117	11	gpgpg	gpgpg	NOUN
aji-178	117	12	,	,	PUNCT
aji-178	117	13	and	and	CCONJ
aji-178	117	14	kk	kk	PROPN
aji-178	117	15	linkers	linker	NOUN
aji-178	117	16	to	to	PART
aji-178	117	17	construct	construct	VERB
aji-178	117	18	the	the	DET
aji-178	117	19	vaccine	vaccine	NOUN
aji-178	117	20	,	,	PUNCT
aji-178	117	21	which	which	PRON
aji-178	117	22	was	be	AUX
aji-178	117	23	assessed	assess	VERB
aji-178	117	24	for	for	ADP
aji-178	117	25	physicochemical	physicochemical	ADJ
aji-178	117	26	properties	property	NOUN
aji-178	117	27	,	,	PUNCT
aji-178	117	28	antigenicity	antigenicity	NOUN
aji-178	117	29	,	,	PUNCT
aji-178	117	30	allergenicity	allergenicity	NOUN
aji-178	117	31	,	,	PUNCT
aji-178	117	32	and	and	CCONJ
aji-178	117	33	toxicity	toxicity	NOUN
aji-178	117	34	.	.	PUNCT
aji-178	118	1	the	the	DET
aji-178	118	2	design	design	NOUN
aji-178	118	3	demonstrated	demonstrate	VERB
aji-178	118	4	stability	stability	NOUN
aji-178	118	5	and	and	CCONJ
aji-178	118	6	strong	strong	ADJ
aji-178	118	7	immunogenic	immunogenic	ADJ
aji-178	118	8	potential	potential	NOUN
aji-178	118	9	.	.	PUNCT
aji-178	119	1	molecular	molecular	ADJ
aji-178	119	2	docking	docking	NOUN
aji-178	119	3	with	with	ADP
aji-178	119	4	the	the	DET
aji-178	119	5	tlr-4	tlr-4	DET
aji-178	119	6	monomer	monomer	NOUN
aji-178	119	7	showed	show	VERB
aji-178	119	8	favorable	favorable	ADJ
aji-178	119	9	binding	binding	ADJ
aji-178	119	10	affinity	affinity	NOUN
aji-178	119	11	,	,	PUNCT
aji-178	119	12	indicating	indicate	VERB
aji-178	119	13	its	its	PRON
aji-178	119	14	original	original	ADJ
aji-178	119	15	research	research	NOUN
aji-178	119	16	article	article	NOUN
aji-178	119	17	https://doi.org/10.9734/aji/2025/v8i1178	https://doi.org/10.9734/aji/2025/v8i1178	ADP
aji-178	119	18	https://pr.sdiarticle5.com/review-history/147582	https://pr.sdiarticle5.com/review-history/147582	NOUN
aji-178	119	19	naseema	naseema	NOUN
aji-178	119	20	;	;	PUNCT
aji-178	119	21	asian	asian	ADJ
aji-178	119	22	j.	j.	PROPN
aji-178	119	23	immunol	immunol	PROPN
aji-178	119	24	.	.	PROPN
aji-178	119	25	,	,	PUNCT
aji-178	119	26	vol	vol	NOUN
aji-178	119	27	.	.	PROPN
aji-178	119	28	8	8	NUM
aji-178	119	29	,	,	PUNCT
aji-178	119	30	no	no	INTJ
aji-178	119	31	.	.	NOUN
aji-178	119	32	1	1	NUM
aji-178	119	33	,	,	PUNCT
aji-178	119	34	pp	pp	ADJ
aji-178	119	35	.	.	PUNCT
aji-178	120	1	269	269	NUM
aji-178	120	2	-	-	SYM
aji-178	120	3	284	284	NUM
aji-178	120	4	,	,	PUNCT
aji-178	120	5	2025	2025	NUM
aji-178	120	6	;	;	PUNCT
aji-178	120	7	article	article	NOUN
aji-178	120	8	no.aji.147582	no.aji.147582	VERB
aji-178	120	9	270	270	NUM
aji-178	120	10	potential	potential	NOUN
aji-178	120	11	as	as	ADP
aji-178	120	12	an	an	DET
aji-178	120	13	effective	effective	ADJ
aji-178	120	14	vaccine	vaccine	NOUN
aji-178	120	15	candidate	candidate	NOUN
aji-178	120	16	.	.	PUNCT
aji-178	121	1	by	by	ADP
aji-178	121	2	applying	apply	VERB
aji-178	121	3	immune	immune	NOUN
aji-178	121	4	-	-	PUNCT
aji-178	121	5	informatics	informatic	NOUN
aji-178	121	6	tools	tool	NOUN
aji-178	121	7	for	for	ADP
aji-178	121	8	precise	precise	ADJ
aji-178	121	9	epitope	epitope	NOUN
aji-178	121	10	selection	selection	NOUN
aji-178	121	11	and	and	CCONJ
aji-178	121	12	vaccine	vaccine	NOUN
aji-178	121	13	design	design	NOUN
aji-178	121	14	,	,	PUNCT
aji-178	121	15	this	this	DET
aji-178	121	16	research	research	NOUN
aji-178	121	17	provides	provide	VERB
aji-178	121	18	a	a	DET
aji-178	121	19	cost	cost	NOUN
aji-178	121	20	-	-	PUNCT
aji-178	121	21	effective	effective	ADJ
aji-178	121	22	strategy	strategy	NOUN
aji-178	121	23	to	to	PART
aji-178	121	24	enhance	enhance	VERB
aji-178	121	25	tb	tb	ADP
aji-178	121	26	prevention	prevention	NOUN
aji-178	121	27	.	.	PUNCT
aji-178	122	1	the	the	DET
aji-178	122	2	study	study	NOUN
aji-178	122	3	offers	offer	VERB
aji-178	122	4	a	a	DET
aji-178	122	5	strong	strong	ADJ
aji-178	122	6	framework	framework	NOUN
aji-178	122	7	for	for	ADP
aji-178	122	8	developing	develop	VERB
aji-178	122	9	next	next	ADJ
aji-178	122	10	-	-	PUNCT
aji-178	122	11	generation	generation	NOUN
aji-178	122	12	tb	tb	ADP
aji-178	122	13	vaccines	vaccine	NOUN
aji-178	122	14	and	and	CCONJ
aji-178	122	15	supports	support	VERB
aji-178	122	16	global	global	ADJ
aji-178	122	17	efforts	effort	NOUN
aji-178	122	18	to	to	PART
aji-178	122	19	eliminate	eliminate	VERB
aji-178	122	20	tuberculosis	tuberculosis	NOUN
aji-178	122	21	by	by	ADP
aji-178	122	22	2035	2035	NUM
aji-178	122	23	.	.	PUNCT
aji-178	123	1	keywords	keyword	NOUN
aji-178	123	2	:	:	PUNCT
aji-178	123	3	mycobacterium	mycobacterium	NOUN
aji-178	123	4	tuberculosis	tuberculosis	NOUN
aji-178	123	5	(	(	PUNCT
aji-178	123	6	m.tb	m.tb	PROPN
aji-178	123	7	)	)	PUNCT
aji-178	123	8	;	;	PUNCT
aji-178	123	9	cytotoxic	cytotoxic	ADJ
aji-178	123	10	t	t	NOUN
aji-178	123	11	lymphocyte	lymphocyte	NOUN
aji-178	123	12	(	(	PUNCT
aji-178	123	13	ctl	ctl	PROPN
aji-178	123	14	)	)	PUNCT
aji-178	123	15	;	;	PUNCT
aji-178	123	16	helper	helper	NOUN
aji-178	123	17	t	t	PROPN
aji-178	123	18	cell	cell	NOUN
aji-178	123	19	(	(	PUNCT
aji-178	123	20	htl	htl	PROPN
aji-178	123	21	)	)	PUNCT
aji-178	123	22	;	;	PUNCT
aji-178	123	23	interferon	interferon	NOUN
aji-178	123	24	-	-	PUNCT
aji-178	123	25	γ	γ	X
aji-178	123	26	(	(	PUNCT
aji-178	123	27	ifn	ifn	PROPN
aji-178	123	28	-	-	PUNCT
aji-178	123	29	γ	γ	NOUN
aji-178	123	30	)	)	PUNCT
aji-178	123	31	;	;	PUNCT
aji-178	123	32	bacillus	bacillus	NOUN
aji-178	123	33	calmette	calmette	NOUN
aji-178	123	34	–	–	PUNCT
aji-178	123	35	guérin	guérin	PROPN
aji-178	123	36	(	(	PUNCT
aji-178	123	37	bcg	bcg	PROPN
aji-178	123	38	)	)	PUNCT
aji-178	123	39	.	.	PUNCT
aji-178	124	1	1	1	X
aji-178	124	2	.	.	X
aji-178	124	3	introduction	introduction	NOUN
aji-178	124	4	“	"	PUNCT
aji-178	124	5	tuberculosis	tuberculosis	NOUN
aji-178	124	6	(	(	PUNCT
aji-178	124	7	tb	tb	NOUN
aji-178	124	8	)	)	PUNCT
aji-178	124	9	is	be	AUX
aji-178	124	10	an	an	DET
aji-178	124	11	airborne	airborne	ADJ
aji-178	124	12	disease	disease	NOUN
aji-178	124	13	caused	cause	VERB
aji-178	124	14	by	by	ADP
aji-178	124	15	the	the	DET
aji-178	124	16	bacterium	bacterium	NOUN
aji-178	124	17	mycobacterium	mycobacterium	NOUN
aji-178	124	18	tuberculosis	tuberculosis	NOUN
aji-178	124	19	.	.	PUNCT
aji-178	125	1	m.	m.	NOUN
aji-178	125	2	tb	tb	X
aji-178	125	3	and	and	CCONJ
aji-178	125	4	its	its	PRON
aji-178	125	5	seven	seven	NUM
aji-178	125	6	closely	closely	ADV
aji-178	125	7	related	relate	VERB
aji-178	125	8	species	specie	NOUN
aji-178	125	9	namely	namely	ADV
aji-178	125	10	m.	m.	NOUN
aji-178	125	11	bovis	bovis	NOUN
aji-178	125	12	,	,	PUNCT
aji-178	125	13	m.	m.	NOUN
aji-178	125	14	africanum	africanum	PROPN
aji-178	125	15	,	,	PUNCT
aji-178	125	16	m.	m.	NOUN
aji-178	125	17	microti	microti	PROPN
aji-178	125	18	,	,	PUNCT
aji-178	125	19	m.	m.	NOUN
aji-178	125	20	caprae	caprae	PROPN
aji-178	125	21	,	,	PUNCT
aji-178	125	22	m.	m.	NOUN
aji-178	125	23	pinnipeti	pinnipeti	PROPN
aji-178	125	24	,	,	PUNCT
aji-178	125	25	m.	m.	NOUN
aji-178	125	26	canetti	canetti	NOUN
aji-178	125	27	and	and	CCONJ
aji-178	125	28	m.	m.	NOUN
aji-178	125	29	munji	munji	PROPN
aji-178	125	30	collectively	collectively	ADV
aji-178	125	31	comprises	comprise	VERB
aji-178	125	32	m.	m.	NOUN
aji-178	125	33	tuberculosis	tuberculosis	NOUN
aji-178	125	34	complex	complex	NOUN
aji-178	125	35	.	.	PUNCT
aji-178	126	1	but	but	CCONJ
aji-178	126	2	not	not	PART
aji-178	126	3	all	all	PRON
aji-178	126	4	of	of	ADP
aji-178	126	5	these	these	DET
aji-178	126	6	species	specie	NOUN
aji-178	126	7	are	be	AUX
aji-178	126	8	reported	report	VERB
aji-178	126	9	to	to	PART
aji-178	126	10	cause	cause	VERB
aji-178	126	11	disease	disease	NOUN
aji-178	126	12	in	in	ADP
aji-178	126	13	humans	human	NOUN
aji-178	126	14	”	"	PUNCT
aji-178	126	15	(	(	PUNCT
aji-178	126	16	beresford	beresford	NOUN
aji-178	126	17	&	&	CCONJ
aji-178	126	18	sadoff	sadoff	NOUN
aji-178	126	19	,	,	PUNCT
aji-178	126	20	2010	2010	NUM
aji-178	126	21	)	)	PUNCT
aji-178	126	22	.	.	PUNCT
aji-178	127	1	“	"	PUNCT
aji-178	127	2	the	the	DET
aji-178	127	3	majority	majority	NOUN
aji-178	127	4	cases	case	NOUN
aji-178	127	5	of	of	ADP
aji-178	127	6	tb	tb	NOUN
aji-178	127	7	are	be	AUX
aji-178	127	8	found	find	VERB
aji-178	127	9	to	to	PART
aji-178	127	10	be	be	AUX
aji-178	127	11	caused	cause	VERB
aji-178	127	12	by	by	ADP
aji-178	127	13	m.	m.	NOUN
aji-178	127	14	tuberculosis	tuberculosis	NOUN
aji-178	127	15	(	(	PUNCT
aji-178	127	16	wheeler	wheeler	NOUN
aji-178	127	17	et	et	NOUN
aji-178	127	18	al	al	PROPN
aji-178	127	19	.	.	PROPN
aji-178	127	20	,	,	PUNCT
aji-178	127	21	2007	2007	NUM
aji-178	127	22	)	)	PUNCT
aji-178	127	23	.	.	PUNCT
aji-178	128	1	tb	tb	PROPN
aji-178	128	2	remains	remain	VERB
aji-178	128	3	one	one	NUM
aji-178	128	4	among	among	ADP
aji-178	128	5	the	the	DET
aji-178	128	6	main	main	ADJ
aji-178	128	7	global	global	ADJ
aji-178	128	8	health	health	NOUN
aji-178	128	9	threats	threat	NOUN
aji-178	128	10	which	which	PRON
aji-178	128	11	causes	cause	VERB
aji-178	128	12	millions	million	NOUN
aji-178	128	13	of	of	ADP
aji-178	128	14	deaths	death	NOUN
aji-178	128	15	annually	annually	ADV
aji-178	128	16	across	across	ADP
aji-178	128	17	the	the	DET
aji-178	128	18	globe	globe	NOUN
aji-178	128	19	.	.	PUNCT
aji-178	129	1	majority	majority	NOUN
aji-178	129	2	of	of	ADP
aji-178	129	3	affected	affected	ADJ
aji-178	129	4	people	people	NOUN
aji-178	129	5	hail	hail	NOUN
aji-178	129	6	from	from	ADP
aji-178	129	7	low	low	ADJ
aji-178	129	8	income	income	NOUN
aji-178	129	9	and	and	CCONJ
aji-178	129	10	middle	middle	ADJ
aji-178	129	11	-	-	PUNCT
aji-178	129	12	income	income	NOUN
aji-178	129	13	countries	country	NOUN
aji-178	129	14	(	(	PUNCT
aji-178	129	15	lmic	lmic	ADJ
aji-178	129	16	)	)	PUNCT
aji-178	129	17	like	like	ADP
aji-178	129	18	countries	country	NOUN
aji-178	129	19	from	from	ADP
aji-178	129	20	african	african	PROPN
aji-178	129	21	subcontinent	subcontinent	PROPN
aji-178	129	22	”	"	PUNCT
aji-178	129	23	(	(	PUNCT
aji-178	129	24	faust	faust	NOUN
aji-178	129	25	et	et	PROPN
aji-178	129	26	al	al	PROPN
aji-178	129	27	.	.	PROPN
aji-178	129	28	,	,	PUNCT
aji-178	129	29	2019	2019	NUM
aji-178	129	30	)	)	PUNCT
aji-178	129	31	.	.	PUNCT
aji-178	130	1	“	"	PUNCT
aji-178	130	2	an	an	DET
aji-178	130	3	estimated	estimate	VERB
aji-178	130	4	10	10	NUM
aji-178	130	5	million	million	NUM
aji-178	130	6	people	people	NOUN
aji-178	130	7	fell	fall	VERB
aji-178	130	8	ill	ill	ADJ
aji-178	130	9	with	with	ADP
aji-178	130	10	tb	tb	NOUN
aji-178	130	11	worldwide	worldwide	ADV
aji-178	130	12	in	in	ADP
aji-178	130	13	2019	2019	NUM
aji-178	130	14	,	,	PUNCT
aji-178	130	15	which	which	PRON
aji-178	130	16	includes	include	VERB
aji-178	130	17	5.6	5.6	NUM
aji-178	130	18	million	million	NUM
aji-178	130	19	men	man	NOUN
aji-178	130	20	,	,	PUNCT
aji-178	130	21	3.2	3.2	NUM
aji-178	130	22	million	million	NUM
aji-178	130	23	women	woman	NOUN
aji-178	130	24	,	,	PUNCT
aji-178	130	25	and	and	CCONJ
aji-178	130	26	1.2	1.2	NUM
aji-178	130	27	million	million	NUM
aji-178	130	28	children	child	NOUN
aji-178	130	29	”	"	PUNCT
aji-178	130	30	(	(	PUNCT
aji-178	130	31	saha	saha	PROPN
aji-178	130	32	&	&	CCONJ
aji-178	130	33	raghava	raghava	PROPN
aji-178	130	34	,	,	PUNCT
aji-178	130	35	2006	2006	NUM
aji-178	130	36	)	)	PUNCT
aji-178	130	37	.	.	PUNCT
aji-178	131	1	“	"	PUNCT
aji-178	131	2	tb	tb	NOUN
aji-178	131	3	is	be	AUX
aji-178	131	4	existing	exist	VERB
aji-178	131	5	in	in	ADP
aji-178	131	6	all	all	DET
aji-178	131	7	countries	country	NOUN
aji-178	131	8	and	and	CCONJ
aji-178	131	9	all	all	DET
aji-178	131	10	age	age	NOUN
aji-178	131	11	groups	group	NOUN
aji-178	131	12	.	.	PUNCT
aji-178	132	1	5	5	NUM
aji-178	132	2	–	–	SYM
aji-178	132	3	15	15	NUM
aji-178	132	4	%	%	NOUN
aji-178	132	5	patients	patient	NOUN
aji-178	132	6	infected	infect	VERB
aji-178	132	7	with	with	ADP
aji-178	132	8	only	only	ADV
aji-178	132	9	tb	tb	NOUN
aji-178	132	10	are	be	AUX
aji-178	132	11	likely	likely	ADJ
aji-178	132	12	to	to	PART
aji-178	132	13	develop	develop	VERB
aji-178	132	14	active	active	ADJ
aji-178	132	15	tb	tb	NOUN
aji-178	132	16	in	in	ADP
aji-178	132	17	their	their	PRON
aji-178	132	18	lifetime	lifetime	NOUN
aji-178	132	19	.	.	PUNCT
aji-178	133	1	tb	tb	X
aji-178	133	2	is	be	AUX
aji-178	133	3	more	more	ADV
aji-178	133	4	severe	severe	ADJ
aji-178	133	5	in	in	ADP
aji-178	133	6	hiv	hiv	PROPN
aji-178	133	7	patients	patient	NOUN
aji-178	133	8	and	and	CCONJ
aji-178	133	9	is	be	AUX
aji-178	133	10	one	one	NUM
aji-178	133	11	of	of	ADP
aji-178	133	12	the	the	DET
aji-178	133	13	main	main	ADJ
aji-178	133	14	reason	reason	NOUN
aji-178	133	15	for	for	ADP
aji-178	133	16	their	their	PRON
aji-178	133	17	mortality	mortality	NOUN
aji-178	133	18	.	.	PUNCT
aji-178	134	1	bcg	bcg	PROPN
aji-178	134	2	(	(	PUNCT
aji-178	134	3	bacille	bacille	PROPN
aji-178	134	4	calmette	calmette	PROPN
aji-178	134	5	guerin	guerin	PROPN
aji-178	134	6	)	)	PUNCT
aji-178	134	7	is	be	AUX
aji-178	134	8	the	the	DET
aji-178	134	9	only	only	ADJ
aji-178	134	10	vaccine	vaccine	NOUN
aji-178	134	11	available	available	ADJ
aji-178	134	12	for	for	ADP
aji-178	134	13	preventing	prevent	VERB
aji-178	134	14	tb	tb	NOUN
aji-178	134	15	in	in	ADP
aji-178	134	16	humans	human	NOUN
aji-178	134	17	.	.	PUNCT
aji-178	135	1	although	although	SCONJ
aji-178	135	2	bcg	bcg	PROPN
aji-178	135	3	is	be	AUX
aji-178	135	4	of	of	ADP
aji-178	135	5	low	low	ADJ
aji-178	135	6	-	-	PUNCT
aji-178	135	7	cost	cost	NOUN
aji-178	135	8	and	and	CCONJ
aji-178	135	9	widely	widely	ADV
aji-178	135	10	used	use	VERB
aji-178	135	11	vaccine	vaccine	NOUN
aji-178	135	12	in	in	ADP
aji-178	135	13	many	many	ADJ
aji-178	135	14	of	of	ADP
aji-178	135	15	the	the	DET
aji-178	135	16	countries	country	NOUN
aji-178	135	17	,	,	PUNCT
aji-178	135	18	its	its	PRON
aji-178	135	19	potency	potency	NOUN
aji-178	135	20	has	have	AUX
aji-178	135	21	varied	vary	VERB
aji-178	135	22	generally	generally	ADV
aji-178	135	23	in	in	ADP
aji-178	135	24	many	many	ADJ
aji-178	135	25	clinical	clinical	ADJ
aji-178	135	26	assays	assay	NOUN
aji-178	135	27	spanned	span	VERB
aji-178	135	28	between	between	ADP
aji-178	135	29	080	080	NUM
aji-178	135	30	%	%	NOUN
aji-178	135	31	(	(	PUNCT
aji-178	135	32	brandt	brandt	PROPN
aji-178	135	33	et	et	PROPN
aji-178	135	34	al	al	PROPN
aji-178	135	35	.	.	PROPN
aji-178	135	36	,	,	PUNCT
aji-178	135	37	2002	2002	NUM
aji-178	135	38	;	;	PUNCT
aji-178	136	1	pablos	pablos	PROPN
aji-178	136	2	-	-	PUNCT
aji-178	136	3	mendez	mendez	PROPN
aji-178	136	4	et	et	PROPN
aji-178	136	5	al	al	PROPN
aji-178	136	6	.	.	PROPN
aji-178	136	7	,	,	PUNCT
aji-178	136	8	2002	2002	NUM
aji-178	136	9	)	)	PUNCT
aji-178	136	10	.	.	PUNCT
aji-178	137	1	it	it	PRON
aji-178	137	2	offers	offer	VERB
aji-178	137	3	poor	poor	ADJ
aji-178	137	4	protection	protection	NOUN
aji-178	137	5	in	in	ADP
aji-178	137	6	adults	adult	NOUN
aji-178	137	7	and	and	CCONJ
aji-178	137	8	adolescents	adolescent	NOUN
aji-178	137	9	against	against	ADP
aji-178	137	10	pulmonary	pulmonary	ADJ
aji-178	137	11	tuberculosis	tuberculosis	NOUN
aji-178	137	12	”	"	PUNCT
aji-178	137	13	(	(	PUNCT
aji-178	137	14	ferraz	ferraz	NOUN
aji-178	137	15	et	et	PROPN
aji-178	137	16	al	al	PROPN
aji-178	137	17	.	.	PROPN
aji-178	137	18	,	,	PUNCT
aji-178	137	19	2004	2004	NUM
aji-178	137	20	)	)	PUNCT
aji-178	137	21	.	.	PUNCT
aji-178	138	1	also	also	ADV
aji-178	138	2	failed	fail	VERB
aji-178	138	3	to	to	PART
aji-178	138	4	treat	treat	VERB
aji-178	138	5	latent	latent	NOUN
aji-178	138	6	tb	tb	ADP
aji-178	138	7	infection	infection	NOUN
aji-178	138	8	(	(	PUNCT
aji-178	138	9	ltbi	ltbi	NOUN
aji-178	138	10	)	)	PUNCT
aji-178	138	11	(	(	PUNCT
aji-178	138	12	weinreich	weinreich	PROPN
aji-178	138	13	olsen	olsen	PROPN
aji-178	138	14	et	et	PROPN
aji-178	138	15	al	al	PROPN
aji-178	138	16	.	.	PROPN
aji-178	138	17	,	,	PUNCT
aji-178	138	18	2000	2000	NUM
aji-178	138	19	)	)	PUNCT
aji-178	138	20	.	.	PUNCT
aji-178	139	1	in	in	ADP
aji-178	139	2	the	the	DET
aji-178	139	3	presence	presence	NOUN
aji-178	139	4	of	of	ADP
aji-178	139	5	immune	immune	NOUN
aji-178	139	6	-	-	PUNCT
aji-178	139	7	suppression	suppression	NOUN
aji-178	139	8	,	,	PUNCT
aji-178	139	9	reversion	reversion	NOUN
aji-178	139	10	of	of	ADP
aji-178	139	11	virulence	virulence	NOUN
aji-178	139	12	may	may	AUX
aji-178	139	13	take	take	VERB
aji-178	139	14	place	place	NOUN
aji-178	139	15	and	and	CCONJ
aji-178	139	16	possible	possible	ADJ
aji-178	139	17	induction	induction	NOUN
aji-178	139	18	of	of	ADP
aji-178	139	19	disease	disease	NOUN
aji-178	139	20	may	may	AUX
aji-178	139	21	happen	happen	VERB
aji-178	139	22	(	(	PUNCT
aji-178	139	23	sharma	sharma	PROPN
aji-178	139	24	et	et	PROPN
aji-178	139	25	al	al	PROPN
aji-178	139	26	.	.	PROPN
aji-178	139	27	,	,	PUNCT
aji-178	139	28	2021	2021	NUM
aji-178	139	29	)	)	PUNCT
aji-178	139	30	.	.	PUNCT
aji-178	140	1	for	for	ADP
aji-178	140	2	these	these	DET
aji-178	140	3	various	various	ADJ
aji-178	140	4	reasons	reason	NOUN
aji-178	140	5	,	,	PUNCT
aji-178	140	6	the	the	PRON
aji-178	140	7	who	who	PRON
aji-178	140	8	has	have	AUX
aji-178	140	9	framed	frame	VERB
aji-178	140	10	“	"	PUNCT
aji-178	140	11	the	the	DET
aji-178	140	12	end	end	NOUN
aji-178	140	13	tb	tb	ADP
aji-178	140	14	strategy	strategy	NOUN
aji-178	140	15	which	which	PRON
aji-178	140	16	targets	target	VERB
aji-178	140	17	the	the	DET
aji-178	140	18	prevention	prevention	NOUN
aji-178	140	19	,	,	PUNCT
aji-178	140	20	care	care	NOUN
aji-178	140	21	and	and	CCONJ
aji-178	140	22	control	control	NOUN
aji-178	140	23	for	for	ADP
aji-178	140	24	tuberculosis	tuberculosis	NOUN
aji-178	140	25	.	.	PUNCT
aji-178	141	1	to	to	PART
aji-178	141	2	meet	meet	VERB
aji-178	141	3	all	all	DET
aji-178	141	4	the	the	DET
aji-178	141	5	requirements	requirement	NOUN
aji-178	141	6	and	and	CCONJ
aji-178	141	7	to	to	PART
aji-178	141	8	satisfy	satisfy	VERB
aji-178	141	9	all	all	DET
aji-178	141	10	the	the	DET
aji-178	141	11	problems	problem	NOUN
aji-178	141	12	associated	associate	VERB
aji-178	141	13	with	with	ADP
aji-178	141	14	mycobacterium	mycobacterium	NOUN
aji-178	141	15	tuberculosis	tuberculosis	NOUN
aji-178	141	16	,	,	PUNCT
aji-178	141	17	there	there	PRON
aji-178	141	18	is	be	VERB
aji-178	141	19	an	an	DET
aji-178	141	20	urge	urge	NOUN
aji-178	141	21	to	to	PART
aji-178	141	22	build	build	VERB
aji-178	141	23	an	an	DET
aji-178	141	24	efficient	efficient	ADJ
aji-178	141	25	vaccine	vaccine	NOUN
aji-178	141	26	,	,	PUNCT
aji-178	141	27	which	which	PRON
aji-178	141	28	offers	offer	VERB
aji-178	141	29	complete	complete	ADJ
aji-178	141	30	safeguard	safeguard	NOUN
aji-178	141	31	against	against	ADP
aji-178	141	32	tuberculosis	tuberculosis	NOUN
aji-178	141	33	”	"	PUNCT
aji-178	141	34	(	(	PUNCT
aji-178	141	35	world	world	NOUN
aji-178	141	36	health	health	NOUN
aji-178	141	37	organization	organization	NOUN
aji-178	141	38	,	,	PUNCT
aji-178	141	39	2018	2018	NUM
aji-178	141	40	)	)	PUNCT
aji-178	141	41	.	.	PUNCT
aji-178	142	1	“	"	PUNCT
aji-178	142	2	in	in	ADP
aji-178	142	3	the	the	DET
aji-178	142	4	current	current	ADJ
aji-178	142	5	study	study	NOUN
aji-178	142	6	,	,	PUNCT
aji-178	142	7	we	we	PRON
aji-178	142	8	have	have	AUX
aji-178	142	9	chosen	choose	VERB
aji-178	142	10	ten	ten	NUM
aji-178	142	11	mycobacterial	mycobacterial	ADJ
aji-178	142	12	proteins	protein	NOUN
aji-178	142	13	from	from	ADP
aji-178	142	14	different	different	ADJ
aji-178	142	15	region	region	NOUN
aji-178	142	16	of	of	ADP
aji-178	142	17	difference	difference	NOUN
aji-178	142	18	(	(	PUNCT
aji-178	142	19	ppe39	ppe39	NOUN
aji-178	142	20	,	,	PUNCT
aji-178	142	21	ppe68	ppe68	NOUN
aji-178	142	22	,	,	PUNCT
aji-178	142	23	rv0310c	rv0310c	PROPN
aji-178	142	24	,	,	PUNCT
aji-178	142	25	pe_pgrs35	pe_pgrs35	ADV
aji-178	142	26	,	,	PUNCT
aji-178	142	27	pe_pgrs_31	pe_pgrs_31	PRON
aji-178	142	28	,	,	PUNCT
aji-178	142	29	cfp10	cfp10	NOUN
aji-178	142	30	,	,	PUNCT
aji-178	142	31	rv1975	rv1975	PROPN
aji-178	142	32	,	,	PUNCT
aji-178	142	33	lpqg	lpqg	NOUN
aji-178	142	34	,	,	PUNCT
aji-178	142	35	esxv	esxv	NOUN
aji-178	142	36	,	,	PUNCT
aji-178	142	37	espj	espj	NOUN
aji-178	142	38	)	)	PUNCT
aji-178	142	39	and	and	CCONJ
aji-178	142	40	an	an	DET
aji-178	142	41	adjuvant	adjuvant	NOUN
aji-178	142	42	(	(	PUNCT
aji-178	142	43	rpfe	rpfe	X
aji-178	142	44	)	)	PUNCT
aji-178	142	45	for	for	ADP
aji-178	142	46	vaccine	vaccine	NOUN
aji-178	142	47	construct	construct	VERB
aji-178	142	48	.	.	PUNCT
aji-178	143	1	pe	pe	PROPN
aji-178	143	2	/	/	SYM
aji-178	143	3	ppe	ppe	NOUN
aji-178	143	4	families	family	NOUN
aji-178	143	5	are	be	AUX
aji-178	143	6	found	find	VERB
aji-178	143	7	to	to	PART
aji-178	143	8	be	be	AUX
aji-178	143	9	associated	associate	VERB
aji-178	143	10	with	with	ADP
aji-178	143	11	pathogenicity	pathogenicity	NOUN
aji-178	143	12	of	of	ADP
aji-178	143	13	mtb	mtb	NOUN
aji-178	143	14	infection	infection	NOUN
aji-178	143	15	.	.	PUNCT
aji-178	144	1	as	as	ADP
aji-178	144	2	in	in	ADP
aji-178	144	3	all	all	DET
aji-178	144	4	pathogenic	pathogenic	ADJ
aji-178	144	5	mycobacteria	mycobacterium	NOUN
aji-178	144	6	,	,	PUNCT
aji-178	144	7	the	the	DET
aji-178	144	8	members	member	NOUN
aji-178	144	9	of	of	ADP
aji-178	144	10	these	these	DET
aji-178	144	11	families	family	NOUN
aji-178	144	12	are	be	AUX
aji-178	144	13	abundant	abundant	ADJ
aji-178	144	14	and	and	CCONJ
aji-178	144	15	comparatively	comparatively	ADV
aji-178	144	16	shows	show	VERB
aji-178	144	17	less	less	ADJ
aji-178	144	18	presence	presence	NOUN
aji-178	144	19	in	in	ADP
aji-178	144	20	nonpathogenic	nonpathogenic	ADJ
aji-178	144	21	mycobacteria	mycobacterium	NOUN
aji-178	144	22	.	.	PUNCT
aji-178	145	1	it	it	PRON
aji-178	145	2	is	be	AUX
aji-178	145	3	observed	observe	VERB
aji-178	145	4	that	that	SCONJ
aji-178	145	5	,	,	PUNCT
aji-178	145	6	pe	pe	PROPN
aji-178	145	7	/	/	SYM
aji-178	145	8	ppe	ppe	NOUN
aji-178	145	9	proteins	protein	NOUN
aji-178	145	10	play	play	VERB
aji-178	145	11	a	a	DET
aji-178	145	12	major	major	ADJ
aji-178	145	13	role	role	NOUN
aji-178	145	14	in	in	ADP
aji-178	145	15	processing	processing	NOUN
aji-178	145	16	of	of	ADP
aji-178	145	17	macrophages	macrophage	NOUN
aji-178	145	18	”	"	PUNCT
aji-178	145	19	(	(	PUNCT
aji-178	145	20	bigi	bigi	PROPN
aji-178	145	21	et	et	PROPN
aji-178	145	22	al	al	PROPN
aji-178	145	23	.	.	PROPN
aji-178	145	24	,	,	PUNCT
aji-178	145	25	2000	2000	NUM
aji-178	145	26	)	)	PUNCT
aji-178	145	27	.	.	PUNCT
aji-178	146	1	adhesion	adhesion	NOUN
aji-178	146	2	of	of	ADP
aji-178	146	3	pathogenic	pathogenic	ADJ
aji-178	146	4	proteins	protein	NOUN
aji-178	146	5	on	on	ADP
aji-178	146	6	the	the	DET
aji-178	146	7	surface	surface	NOUN
aji-178	146	8	of	of	ADP
aji-178	146	9	macrophage	macrophage	ADJ
aji-178	146	10	receptors	receptor	NOUN
aji-178	146	11	,	,	PUNCT
aji-178	146	12	immune	immune	ADJ
aji-178	146	13	response	response	NOUN
aji-178	146	14	to	to	ADP
aji-178	146	15	pathogenic	pathogenic	ADJ
aji-178	146	16	proteins	protein	NOUN
aji-178	146	17	,	,	PUNCT
aji-178	146	18	resistance	resistance	NOUN
aji-178	146	19	of	of	ADP
aji-178	146	20	intracellular	intracellular	ADJ
aji-178	146	21	stress	stress	NOUN
aji-178	146	22	,	,	PUNCT
aji-178	146	23	phagocytosis	phagocytosis	NOUN
aji-178	146	24	,	,	PUNCT
aji-178	146	25	intracellular	intracellular	ADJ
aji-178	146	26	survival	survival	NOUN
aji-178	146	27	in	in	ADP
aji-178	146	28	the	the	DET
aji-178	146	29	host	host	NOUN
aji-178	146	30	environment	environment	NOUN
aji-178	146	31	and	and	CCONJ
aji-178	146	32	regulation	regulation	NOUN
aji-178	146	33	of	of	ADP
aji-178	146	34	cell	cell	NOUN
aji-178	146	35	fate	fate	NOUN
aji-178	146	36	are	be	AUX
aji-178	146	37	the	the	DET
aji-178	146	38	key	key	ADJ
aji-178	146	39	events	event	NOUN
aji-178	146	40	involved	involve	VERB
aji-178	146	41	in	in	ADP
aji-178	146	42	the	the	DET
aji-178	146	43	host	host	NOUN
aji-178	146	44	-	-	PUNCT
aji-178	146	45	pathogen	pathogen	NOUN
aji-178	146	46	interactions	interaction	NOUN
aji-178	146	47	.	.	PUNCT
aji-178	147	1	during	during	ADP
aji-178	147	2	various	various	ADJ
aji-178	147	3	stages	stage	NOUN
aji-178	147	4	of	of	ADP
aji-178	147	5	infection	infection	NOUN
aji-178	147	6	,	,	PUNCT
aji-178	147	7	the	the	DET
aji-178	147	8	cfp10	cfp10	NOUN
aji-178	147	9	/	/	SYM
aji-178	147	10	esat6	esat6	NOUN
aji-178	147	11	complex	complex	NOUN
aji-178	147	12	in	in	ADP
aji-178	147	13	mycobacterium	mycobacterium	NOUN
aji-178	147	14	tuberculosis	tuberculosis	NOUN
aji-178	147	15	could	could	AUX
aji-178	147	16	play	play	VERB
aji-178	147	17	a	a	DET
aji-178	147	18	role	role	NOUN
aji-178	147	19	in	in	ADP
aji-178	147	20	regulating	regulate	VERB
aji-178	147	21	macrophage	macrophage	ADJ
aji-178	147	22	death	death	NOUN
aji-178	147	23	(	(	PUNCT
aji-178	147	24	trott	trott	PROPN
aji-178	147	25	&	&	CCONJ
aji-178	147	26	olson	olson	PROPN
aji-178	147	27	,	,	PUNCT
aji-178	147	28	2010	2010	NUM
aji-178	147	29	)	)	PUNCT
aji-178	147	30	.	.	PUNCT
aji-178	148	1	“	"	PUNCT
aji-178	148	2	the	the	DET
aji-178	148	3	major	major	ADJ
aji-178	148	4	advantage	advantage	NOUN
aji-178	148	5	in	in	ADP
aji-178	148	6	peptide	peptide	NOUN
aji-178	148	7	-	-	PUNCT
aji-178	148	8	based	base	VERB
aji-178	148	9	vaccines	vaccine	NOUN
aji-178	148	10	is	be	AUX
aji-178	148	11	the	the	DET
aji-178	148	12	absence	absence	NOUN
aji-178	148	13	of	of	ADP
aji-178	148	14	live	live	ADJ
aji-178	148	15	or	or	CCONJ
aji-178	148	16	attenuated	attenuate	VERB
aji-178	148	17	infectious	infectious	ADJ
aji-178	148	18	materials	material	NOUN
aji-178	148	19	.	.	PUNCT
aji-178	149	1	hence	hence	ADV
aji-178	149	2	there	there	PRON
aji-178	149	3	is	be	VERB
aji-178	149	4	zero	zero	NUM
aji-178	149	5	risk	risk	NOUN
aji-178	149	6	for	for	ADP
aji-178	149	7	reversion	reversion	NOUN
aji-178	149	8	of	of	ADP
aji-178	149	9	virulence	virulence	NOUN
aji-178	149	10	”	"	PUNCT
aji-178	149	11	(	(	PUNCT
aji-178	149	12	trunz	trunz	NOUN
aji-178	149	13	et	et	NOUN
aji-178	149	14	al	al	PROPN
aji-178	149	15	.	.	PROPN
aji-178	149	16	,	,	PUNCT
aji-178	149	17	2006	2006	NUM
aji-178	149	18	)	)	PUNCT
aji-178	149	19	.	.	PUNCT
aji-178	150	1	“	"	PUNCT
aji-178	150	2	to	to	PART
aji-178	150	3	enhance	enhance	VERB
aji-178	150	4	the	the	DET
aji-178	150	5	stability	stability	NOUN
aji-178	150	6	,	,	PUNCT
aji-178	150	7	solubility	solubility	NOUN
aji-178	150	8	lipid	lipid	NOUN
aji-178	150	9	,	,	PUNCT
aji-178	150	10	carbohydrate	carbohydrate	NOUN
aji-178	150	11	and	and	CCONJ
aji-178	150	12	phosphates	phosphate	NOUN
aji-178	150	13	groups	group	NOUN
aji-178	150	14	can	can	AUX
aji-178	150	15	be	be	AUX
aji-178	150	16	readily	readily	ADV
aji-178	150	17	introduced	introduce	VERB
aji-178	150	18	.	.	PUNCT
aji-178	151	1	one	one	NUM
aji-178	151	2	major	major	ADJ
aji-178	151	3	advantage	advantage	NOUN
aji-178	151	4	of	of	ADP
aji-178	151	5	epitope	epitope	NOUN
aji-178	151	6	-	-	PUNCT
aji-178	151	7	based	base	VERB
aji-178	151	8	vaccines	vaccine	NOUN
aji-178	151	9	is	be	AUX
aji-178	151	10	that	that	SCONJ
aji-178	151	11	they	they	PRON
aji-178	151	12	rely	rely	VERB
aji-178	151	13	on	on	ADP
aji-178	151	14	a	a	DET
aji-178	151	15	small	small	ADJ
aji-178	151	16	,	,	PUNCT
aji-178	151	17	precisely	precisely	ADV
aji-178	151	18	defined	define	VERB
aji-178	151	19	antigen	antigen	ADV
aji-178	151	20	,	,	PUNCT
aji-178	151	21	making	make	VERB
aji-178	151	22	it	it	PRON
aji-178	151	23	easier	easy	ADJ
aji-178	151	24	to	to	PART
aji-178	151	25	understand	understand	VERB
aji-178	151	26	and	and	CCONJ
aji-178	151	27	evaluate	evaluate	VERB
aji-178	151	28	its	its	PRON
aji-178	151	29	immunogenicity	immunogenicity	NOUN
aji-178	151	30	and	and	CCONJ
aji-178	151	31	antigenicity	antigenicity	NOUN
aji-178	151	32	(	(	PUNCT
aji-178	151	33	choi	choi	PROPN
aji-178	151	34	et	et	PROPN
aji-178	151	35	al	al	PROPN
aji-178	151	36	.	.	PROPN
aji-178	151	37	,	,	PUNCT
aji-178	151	38	2015	2015	NUM
aji-178	151	39	)	)	PUNCT
aji-178	151	40	.	.	PUNCT
aji-178	152	1	the	the	DET
aji-178	152	2	induction	induction	NOUN
aji-178	152	3	of	of	ADP
aji-178	152	4	neutralizing	neutralize	VERB
aji-178	152	5	antibodies	antibody	NOUN
aji-178	152	6	and	and	CCONJ
aji-178	152	7	a	a	DET
aji-178	152	8	protective	protective	ADJ
aji-178	152	9	t	t	NOUN
aji-178	152	10	helper	helper	NOUN
aji-178	152	11	and	and	CCONJ
aji-178	152	12	a	a	DET
aji-178	152	13	ctl	ctl	NOUN
aji-178	152	14	response	response	NOUN
aji-178	152	15	by	by	ADP
aji-178	152	16	t	t	PROPN
aji-178	152	17	cell	cell	NOUN
aji-178	152	18	and	and	CCONJ
aji-178	152	19	b	b	NOUN
aji-178	152	20	cell	cell	NOUN
aji-178	152	21	epitope	epitope	NOUN
aji-178	152	22	must	must	AUX
aji-178	152	23	be	be	AUX
aji-178	152	24	required	require	VERB
aji-178	152	25	for	for	ADP
aji-178	152	26	a	a	DET
aji-178	152	27	good	good	ADJ
aji-178	152	28	tb	tb	ADP
aji-178	152	29	vaccine	vaccine	NOUN
aji-178	152	30	.	.	PUNCT
aji-178	153	1	to	to	PART
aji-178	153	2	maximize	maximize	VERB
aji-178	153	3	coverage	coverage	NOUN
aji-178	153	4	,	,	PUNCT
aji-178	153	5	the	the	DET
aji-178	153	6	ctl	ctl	PROPN
aji-178	153	7	and	and	CCONJ
aji-178	153	8	htl	htl	PROPN
aji-178	153	9	epitopes	epitope	NOUN
aji-178	153	10	were	be	AUX
aji-178	153	11	tested	test	VERB
aji-178	153	12	for	for	ADP
aji-178	153	13	their	their	PRON
aji-178	153	14	ability	ability	NOUN
aji-178	153	15	to	to	PART
aji-178	153	16	bind	bind	VERB
aji-178	153	17	with	with	ADP
aji-178	153	18	the	the	DET
aji-178	153	19	most	most	ADV
aji-178	153	20	prevalent	prevalent	ADJ
aji-178	153	21	human	human	PROPN
aji-178	153	22	hla	hla	PROPN
aji-178	153	23	alleles	allele	NOUN
aji-178	153	24	for	for	ADP
aji-178	153	25	mhc	mhc	PROPN
aji-178	153	26	class	class	PROPN
aji-178	153	27	i	i	PROPN
aji-178	153	28	and	and	CCONJ
aji-178	153	29	ii	ii	PROPN
aji-178	153	30	(	(	PUNCT
aji-178	153	31	martinot	martinot	ADV
aji-178	153	32	et	et	PROPN
aji-178	153	33	al	al	PROPN
aji-178	153	34	.	.	PROPN
aji-178	153	35	,	,	PUNCT
aji-178	153	36	2016	2016	NUM
aji-178	153	37	)	)	PUNCT
aji-178	153	38	.	.	PUNCT
aji-178	154	1	“	"	PUNCT
aji-178	154	2	the	the	DET
aji-178	154	3	adjuvant	adjuvant	ADJ
aji-178	154	4	rfpe	rfpe	NOUN
aji-178	154	5	was	be	AUX
aji-178	154	6	included	include	VERB
aji-178	154	7	to	to	ADP
aji-178	154	8	the	the	DET
aji-178	154	9	vaccine	vaccine	NOUN
aji-178	154	10	draft	draft	VERB
aji-178	154	11	to	to	PART
aji-178	154	12	enhance	enhance	VERB
aji-178	154	13	its	its	PRON
aji-178	154	14	immunogenicity	immunogenicity	NOUN
aji-178	154	15	”	"	PUNCT
aji-178	154	16	(	(	PUNCT
aji-178	154	17	bellini	bellini	X
aji-178	154	18	&	&	CCONJ
aji-178	154	19	horváti	horváti	ADJ
aji-178	154	20	,	,	PUNCT
aji-178	154	21	2020	2020	NUM
aji-178	154	22	)	)	PUNCT
aji-178	154	23	.	.	PUNCT
aji-178	155	1	several	several	ADJ
aji-178	155	2	vaccine	vaccine	NOUN
aji-178	155	3	sequences	sequence	NOUN
aji-178	155	4	were	be	AUX
aji-178	155	5	generated	generate	VERB
aji-178	155	6	and	and	CCONJ
aji-178	155	7	analyzed	analyze	VERB
aji-178	155	8	for	for	ADP
aji-178	155	9	allergenicity	allergenicity	NOUN
aji-178	155	10	,	,	PUNCT
aji-178	155	11	toxicity	toxicity	NOUN
aji-178	155	12	,	,	PUNCT
aji-178	155	13	antigenicity	antigenicity	NOUN
aji-178	155	14	,	,	PUNCT
aji-178	155	15	and	and	CCONJ
aji-178	155	16	important	important	ADJ
aji-178	155	17	physicochemical	physicochemical	ADJ
aji-178	155	18	properties	property	NOUN
aji-178	155	19	such	such	ADJ
aji-178	155	20	naseema	naseema	NOUN
aji-178	155	21	;	;	PUNCT
aji-178	155	22	asian	asian	ADJ
aji-178	155	23	j.	j.	PROPN
aji-178	155	24	immunol	immunol	PROPN
aji-178	155	25	.	.	PROPN
aji-178	155	26	,	,	PUNCT
aji-178	155	27	vol	vol	NOUN
aji-178	155	28	.	.	PROPN
aji-178	155	29	8	8	NUM
aji-178	155	30	,	,	PUNCT
aji-178	155	31	no	no	INTJ
aji-178	155	32	.	.	NOUN
aji-178	155	33	1	1	NUM
aji-178	155	34	,	,	PUNCT
aji-178	155	35	pp	pp	ADJ
aji-178	155	36	.	.	PUNCT
aji-178	156	1	269	269	NUM
aji-178	156	2	-	-	SYM
aji-178	156	3	284	284	NUM
aji-178	156	4	,	,	PUNCT
aji-178	156	5	2025	2025	NUM
aji-178	156	6	;	;	PUNCT
aji-178	156	7	article	article	NOUN
aji-178	156	8	no.aji.147582	no.aji.147582	NOUN
aji-178	156	9	271	271	NUM
aji-178	156	10	as	as	ADP
aji-178	156	11	isoelectric	isoelectric	ADJ
aji-178	156	12	point	point	NOUN
aji-178	156	13	,	,	PUNCT
aji-178	156	14	solubility	solubility	NOUN
aji-178	156	15	,	,	PUNCT
aji-178	156	16	and	and	CCONJ
aji-178	156	17	half	half	ADJ
aji-178	156	18	-	-	PUNCT
aji-178	156	19	life	life	NOUN
aji-178	156	20	in	in	ADP
aji-178	156	21	different	different	ADJ
aji-178	156	22	hosts	host	NOUN
aji-178	156	23	”	"	PUNCT
aji-178	156	24	(	(	PUNCT
aji-178	156	25	kelley	kelley	PROPN
aji-178	156	26	et	et	PROPN
aji-178	156	27	al	al	PROPN
aji-178	156	28	.	.	PROPN
aji-178	156	29	,	,	PUNCT
aji-178	156	30	2015	2015	NUM
aji-178	156	31	)	)	PUNCT
aji-178	156	32	.	.	PUNCT
aji-178	157	1	“	"	PUNCT
aji-178	157	2	homology	homology	NOUN
aji-178	157	3	modeling	modeling	NOUN
aji-178	157	4	was	be	AUX
aji-178	157	5	carried	carry	VERB
aji-178	157	6	out	out	ADP
aji-178	157	7	for	for	ADP
aji-178	157	8	all	all	DET
aji-178	157	9	vaccine	vaccine	NOUN
aji-178	157	10	sequences	sequence	NOUN
aji-178	157	11	,	,	PUNCT
aji-178	157	12	and	and	CCONJ
aji-178	157	13	the	the	DET
aji-178	157	14	best	good	ADJ
aji-178	157	15	3d	3d	NUM
aji-178	157	16	model	model	NOUN
aji-178	157	17	was	be	AUX
aji-178	157	18	chosen	choose	VERB
aji-178	157	19	based	base	VERB
aji-178	157	20	on	on	ADP
aji-178	157	21	the	the	DET
aji-178	157	22	recommendations	recommendation	NOUN
aji-178	157	23	of	of	ADP
aji-178	157	24	online	online	ADJ
aji-178	157	25	servers	server	NOUN
aji-178	157	26	”	"	PUNCT
aji-178	157	27	(	(	PUNCT
aji-178	157	28	rapin	rapin	NOUN
aji-178	157	29	et	et	PROPN
aji-178	157	30	al	al	PROPN
aji-178	157	31	.	.	PROPN
aji-178	157	32	,	,	PUNCT
aji-178	157	33	2010	2010	NUM
aji-178	157	34	)	)	PUNCT
aji-178	157	35	.	.	PUNCT
aji-178	158	1	the	the	DET
aji-178	158	2	stereochemical	stereochemical	ADJ
aji-178	158	3	geometry	geometry	NOUN
aji-178	158	4	of	of	ADP
aji-178	158	5	this	this	DET
aji-178	158	6	model	model	NOUN
aji-178	158	7	was	be	AUX
aji-178	158	8	then	then	ADV
aji-178	158	9	evaluated	evaluate	VERB
aji-178	158	10	,	,	PUNCT
aji-178	158	11	both	both	CCONJ
aji-178	158	12	at	at	ADP
aji-178	158	13	the	the	DET
aji-178	158	14	residue	residue	NOUN
aji-178	158	15	level	level	NOUN
aji-178	158	16	and	and	CCONJ
aji-178	158	17	overall	overall	ADJ
aji-178	158	18	structure	structure	NOUN
aji-178	158	19	(	(	PUNCT
aji-178	158	20	sanches	sanche	NOUN
aji-178	158	21	et	et	PROPN
aji-178	158	22	al	al	PROPN
aji-178	158	23	.	.	PROPN
aji-178	158	24	,	,	PUNCT
aji-178	158	25	2021	2021	NUM
aji-178	158	26	)	)	PUNCT
aji-178	158	27	.	.	PUNCT
aji-178	159	1	finally	finally	ADV
aji-178	159	2	,	,	PUNCT
aji-178	159	3	molecular	molecular	ADJ
aji-178	159	4	docking	docking	NOUN
aji-178	159	5	was	be	AUX
aji-178	159	6	performed	perform	VERB
aji-178	159	7	between	between	ADP
aji-178	159	8	the	the	DET
aji-178	159	9	optimized	optimize	VERB
aji-178	159	10	3d	3d	NUM
aji-178	159	11	vaccine	vaccine	NOUN
aji-178	159	12	model	model	NOUN
aji-178	159	13	and	and	CCONJ
aji-178	159	14	tlr4	tlr4	NOUN
aji-178	159	15	to	to	PART
aji-178	159	16	study	study	VERB
aji-178	159	17	binding	binding	ADJ
aji-178	159	18	interactions	interaction	NOUN
aji-178	159	19	.	.	PUNCT
aji-178	160	1	2	2	X
aji-178	160	2	.	.	X
aji-178	160	3	methods	method	NOUN
aji-178	160	4	and	and	CCONJ
aji-178	160	5	methodology	methodology	NOUN
aji-178	160	6	1	1	NUM
aji-178	160	7	.	.	PUNCT
aji-178	161	1	htl	htl	PROPN
aji-178	161	2	epitopes	epitopes	PROPN
aji-178	161	3	prediction	prediction	NOUN
aji-178	161	4	:	:	PUNCT
aji-178	161	5	helper	helper	NOUN
aji-178	161	6	t	t	PROPN
aji-178	161	7	lymphocyte	lymphocyte	NOUN
aji-178	161	8	(	(	PUNCT
aji-178	161	9	htl	htl	PROPN
aji-178	161	10	)	)	PUNCT
aji-178	161	11	epitopes	epitope	NOUN
aji-178	161	12	were	be	AUX
aji-178	161	13	forecasted	forecast	VERB
aji-178	161	14	using	use	VERB
aji-178	161	15	the	the	DET
aji-178	161	16	netmhciipan	netmhciipan	NOUN
aji-178	161	17	4.0	4.0	NUM
aji-178	161	18	server	server	NOUN
aji-178	161	19	,	,	PUNCT
aji-178	161	20	which	which	PRON
aji-178	161	21	is	be	AUX
aji-178	161	22	an	an	DET
aji-178	161	23	online	online	ADJ
aji-178	161	24	tool	tool	NOUN
aji-178	161	25	for	for	ADP
aji-178	161	26	identifying	identify	VERB
aji-178	161	27	immune	immune	ADJ
aji-178	161	28	epitopes	epitope	NOUN
aji-178	161	29	based	base	VERB
aji-178	161	30	on	on	ADP
aji-178	161	31	a	a	DET
aji-178	161	32	large	large	ADJ
aji-178	161	33	collection	collection	NOUN
aji-178	161	34	of	of	ADP
aji-178	161	35	experimentally	experimentally	ADV
aji-178	161	36	validated	validate	VERB
aji-178	161	37	data	datum	NOUN
aji-178	161	38	.	.	PUNCT
aji-178	162	1	all	all	DET
aji-178	162	2	protein	protein	NOUN
aji-178	162	3	sequences	sequence	NOUN
aji-178	162	4	of	of	ADP
aji-178	162	5	the	the	DET
aji-178	162	6	chosen	choose	VERB
aji-178	162	7	antigens	antigen	NOUN
aji-178	162	8	were	be	AUX
aji-178	162	9	handed	hand	VERB
aji-178	162	10	in	in	ADP
aji-178	162	11	simultaneously	simultaneously	ADV
aji-178	162	12	in	in	ADP
aji-178	162	13	fasta	fasta	PROPN
aji-178	162	14	format	format	NOUN
aji-178	162	15	.	.	PUNCT
aji-178	163	1	the	the	DET
aji-178	163	2	default	default	NOUN
aji-178	163	3	settings	setting	NOUN
aji-178	163	4	were	be	AUX
aji-178	163	5	used	use	VERB
aji-178	163	6	to	to	PART
aji-178	163	7	predict	predict	VERB
aji-178	163	8	epitopes	epitope	NOUN
aji-178	163	9	across	across	ADP
aji-178	163	10	the	the	DET
aji-178	163	11	total	total	ADJ
aji-178	163	12	human	human	PROPN
aji-178	163	13	hla	hla	PROPN
aji-178	163	14	reference	reference	NOUN
aji-178	163	15	set	set	NOUN
aji-178	163	16	,	,	PUNCT
aji-178	163	17	specifying	specify	VERB
aji-178	163	18	an	an	DET
aji-178	163	19	epitope	epitope	NOUN
aji-178	163	20	length	length	NOUN
aji-178	163	21	of	of	ADP
aji-178	163	22	9	9	NUM
aji-178	163	23	amino	amino	NOUN
aji-178	163	24	acids	acid	NOUN
aji-178	163	25	.	.	PUNCT
aji-178	164	1	the	the	DET
aji-178	164	2	predicted	predict	VERB
aji-178	164	3	epitopes	epitope	NOUN
aji-178	164	4	were	be	AUX
aji-178	164	5	then	then	ADV
aji-178	164	6	ranked	rank	VERB
aji-178	164	7	and	and	CCONJ
aji-178	164	8	scored	score	VERB
aji-178	164	9	according	accord	VERB
aji-178	164	10	to	to	ADP
aji-178	164	11	their	their	PRON
aji-178	164	12	binding	bind	VERB
aji-178	164	13	affinity	affinity	NOUN
aji-178	164	14	.	.	PUNCT
aji-178	165	1	2	2	X
aji-178	165	2	.	.	X
aji-178	165	3	ctl	ctl	PROPN
aji-178	165	4	epitopes	epitopes	PROPN
aji-178	165	5	prediction	prediction	NOUN
aji-178	165	6	:	:	PUNCT
aji-178	165	7	cytotoxic	cytotoxic	ADJ
aji-178	165	8	t	t	NOUN
aji-178	165	9	lymphocyte	lymphocyte	NOUN
aji-178	165	10	(	(	PUNCT
aji-178	165	11	ctl	ctl	PROPN
aji-178	165	12	)	)	PUNCT
aji-178	165	13	epitopes	epitope	NOUN
aji-178	165	14	were	be	AUX
aji-178	165	15	predicted	predict	VERB
aji-178	165	16	using	use	VERB
aji-178	165	17	the	the	DET
aji-178	165	18	netctlpan	netctlpan	NOUN
aji-178	165	19	1.2	1.2	NUM
aji-178	165	20	server	server	NOUN
aji-178	165	21	.	.	PUNCT
aji-178	166	1	all	all	DET
aji-178	166	2	amino	amino	NOUN
aji-178	166	3	acid	acid	NOUN
aji-178	166	4	sequences	sequence	NOUN
aji-178	166	5	from	from	ADP
aji-178	166	6	the	the	DET
aji-178	166	7	selected	select	VERB
aji-178	166	8	proteins	protein	NOUN
aji-178	166	9	were	be	AUX
aji-178	166	10	uploaded	upload	VERB
aji-178	166	11	together	together	ADV
aji-178	166	12	in	in	ADP
aji-178	166	13	fasta	fasta	PROPN
aji-178	166	14	format	format	NOUN
aji-178	166	15	.	.	PUNCT
aji-178	167	1	using	use	VERB
aji-178	167	2	the	the	DET
aji-178	167	3	full	full	ADJ
aji-178	167	4	human	human	PROPN
aji-178	167	5	hla	hla	PROPN
aji-178	167	6	reference	reference	NOUN
aji-178	167	7	set	set	NOUN
aji-178	167	8	,	,	PUNCT
aji-178	167	9	9	9	NUM
aji-178	167	10	-	-	PUNCT
aji-178	167	11	mer	mer	NOUN
aji-178	167	12	epitopes	epitope	NOUN
aji-178	167	13	were	be	AUX
aji-178	167	14	predicted	predict	VERB
aji-178	167	15	with	with	ADP
aji-178	167	16	default	default	NOUN
aji-178	167	17	settings	setting	NOUN
aji-178	167	18	,	,	PUNCT
aji-178	167	19	and	and	CCONJ
aji-178	167	20	the	the	DET
aji-178	167	21	resulting	result	VERB
aji-178	167	22	peptides	peptide	NOUN
aji-178	167	23	were	be	AUX
aji-178	167	24	ranked	rank	VERB
aji-178	167	25	by	by	ADP
aji-178	167	26	their	their	PRON
aji-178	167	27	scores	score	NOUN
aji-178	167	28	.	.	PUNCT
aji-178	168	1	the	the	DET
aji-178	168	2	chosen	choose	VERB
aji-178	168	3	epitopes	epitope	NOUN
aji-178	168	4	were	be	AUX
aji-178	168	5	then	then	ADV
aji-178	168	6	examined	examine	VERB
aji-178	168	7	for	for	ADP
aji-178	168	8	their	their	PRON
aji-178	168	9	allergenic	allergenic	ADJ
aji-178	168	10	,	,	PUNCT
aji-178	168	11	toxic	toxic	ADJ
aji-178	168	12	,	,	PUNCT
aji-178	168	13	and	and	CCONJ
aji-178	168	14	antigenic	antigenic	ADJ
aji-178	168	15	properties	property	NOUN
aji-178	168	16	.	.	PUNCT
aji-178	169	1	mhc	mhc	PROPN
aji-178	169	2	i	i	PROPN
aji-178	169	3	–	–	PUNCT
aji-178	169	4	related	relate	VERB
aji-178	169	5	hla	hla	PROPN
aji-178	169	6	-	-	PUNCT
aji-178	169	7	c	c	NOUN
aji-178	169	8	epitopes	epitope	NOUN
aji-178	169	9	were	be	AUX
aji-178	169	10	identified	identify	VERB
aji-178	169	11	with	with	ADP
aji-178	169	12	the	the	DET
aji-178	169	13	netctlpan	netctlpan	NOUN
aji-178	169	14	1.1	1.1	NUM
aji-178	169	15	server	server	NOUN
aji-178	169	16	,	,	PUNCT
aji-178	169	17	with	with	ADP
aji-178	169	18	all	all	DET
aji-178	169	19	selected	select	VERB
aji-178	169	20	protein	protein	NOUN
aji-178	169	21	sequences	sequence	NOUN
aji-178	169	22	submitted	submit	VERB
aji-178	169	23	at	at	ADP
aji-178	169	24	once	once	ADV
aji-178	169	25	in	in	ADP
aji-178	169	26	fasta	fasta	PROPN
aji-178	169	27	format.this	format.this	DET
aji-178	169	28	prediction	prediction	NOUN
aji-178	169	29	is	be	AUX
aji-178	169	30	based	base	VERB
aji-178	169	31	on	on	ADP
aji-178	169	32	mhc	mhc	PROPN
aji-178	169	33	class	class	PROPN
aji-178	169	34	–	–	PUNCT
aji-178	169	35	i	i	PRON
aji-178	169	36	binding	bind	VERB
aji-178	169	37	affinity	affinity	NOUN
aji-178	169	38	,	,	PUNCT
aji-178	169	39	proteasomal	proteasomal	ADJ
aji-178	169	40	cleavage	cleavage	NOUN
aji-178	169	41	efficiency	efficiency	NOUN
aji-178	169	42	and	and	CCONJ
aji-178	169	43	tap	tap	NOUN
aji-178	169	44	transport	transport	NOUN
aji-178	169	45	efficiency	efficiency	NOUN
aji-178	169	46	.	.	PUNCT
aji-178	170	1	20	20	NUM
aji-178	170	2	alleles	allele	NOUN
aji-178	170	3	of	of	ADP
aji-178	170	4	hla	hla	NOUN
aji-178	170	5	-	-	PUNCT
aji-178	170	6	c	c	NOUN
aji-178	170	7	haplotype	haplotype	NOUN
aji-178	170	8	were	be	AUX
aji-178	170	9	given	give	VERB
aji-178	170	10	as	as	ADP
aji-178	170	11	input	input	NOUN
aji-178	170	12	for	for	ADP
aji-178	170	13	prediction	prediction	NOUN
aji-178	170	14	.	.	PUNCT
aji-178	171	1	these	these	DET
aji-178	171	2	20	20	NUM
aji-178	171	3	alleles	allele	NOUN
aji-178	171	4	were	be	AUX
aji-178	171	5	taken	take	VERB
aji-178	171	6	as	as	ADP
aji-178	171	7	a	a	DET
aji-178	171	8	reference	reference	NOUN
aji-178	171	9	set	set	VERB
aji-178	171	10	from	from	ADP
aji-178	171	11	iedb	iedb	NOUN
aji-178	171	12	.	.	PUNCT
aji-178	172	1	in	in	ADP
aji-178	172	2	total	total	ADJ
aji-178	172	3	five	five	NUM
aji-178	172	4	hla	hla	PROPN
aji-178	172	5	-c	-c	PUNCT
aji-178	172	6	epitopes	epitope	NOUN
aji-178	172	7	were	be	AUX
aji-178	172	8	chosen	choose	VERB
aji-178	172	9	for	for	SCONJ
aji-178	172	10	the	the	DET
aji-178	172	11	vaccine	vaccine	NOUN
aji-178	172	12	construct	construct	VERB
aji-178	172	13	.	.	PUNCT
aji-178	173	1	3	3	X
aji-178	173	2	.	.	X
aji-178	173	3	b‑cell	b‑cell	PROPN
aji-178	173	4	epitopes	epitope	NOUN
aji-178	173	5	prediction	prediction	NOUN
aji-178	173	6	:	:	PUNCT
aji-178	173	7	the	the	DET
aji-178	173	8	b	b	PROPN
aji-178	173	9	cell	cell	NOUN
aji-178	173	10	epitopes	epitope	NOUN
aji-178	173	11	were	be	AUX
aji-178	173	12	predicted	predict	VERB
aji-178	173	13	using	use	VERB
aji-178	173	14	abcpred	abcpre	VERB
aji-178	173	15	web	web	NOUN
aji-178	173	16	server	server	NOUN
aji-178	173	17	.	.	PUNCT
aji-178	174	1	all	all	DET
aji-178	174	2	the	the	DET
aji-178	174	3	amino	amino	ADJ
aji-178	174	4	acids	acid	NOUN
aji-178	174	5	sequences	sequence	NOUN
aji-178	174	6	of	of	ADP
aji-178	174	7	the	the	DET
aji-178	174	8	selected	select	VERB
aji-178	174	9	proteins	protein	NOUN
aji-178	174	10	were	be	AUX
aji-178	174	11	submitted	submit	VERB
aji-178	174	12	at	at	ADP
aji-178	174	13	a	a	DET
aji-178	174	14	time	time	NOUN
aji-178	174	15	in	in	ADP
aji-178	174	16	fasta	fasta	PROPN
aji-178	174	17	format	format	NOUN
aji-178	174	18	(	(	PUNCT
aji-178	174	19	hougardy	hougardy	NOUN
aji-178	174	20	et	et	PROPN
aji-178	174	21	al	al	PROPN
aji-178	174	22	.	.	PROPN
aji-178	174	23	,	,	PUNCT
aji-178	174	24	2007	2007	NUM
aji-178	174	25	)	)	PUNCT
aji-178	174	26	.	.	PUNCT
aji-178	175	1	the	the	DET
aji-178	175	2	top	top	ADJ
aji-178	175	3	30	30	NUM
aji-178	175	4	epitopes	epitope	NOUN
aji-178	175	5	were	be	AUX
aji-178	175	6	selected	select	VERB
aji-178	175	7	based	base	VERB
aji-178	175	8	on	on	ADP
aji-178	175	9	the	the	DET
aji-178	175	10	score	score	NOUN
aji-178	175	11	and	and	CCONJ
aji-178	175	12	was	be	AUX
aji-178	175	13	further	far	ADV
aji-178	175	14	analyzed	analyze	VERB
aji-178	175	15	for	for	ADP
aji-178	175	16	antigenicity	antigenicity	NOUN
aji-178	175	17	,	,	PUNCT
aji-178	175	18	toxicity	toxicity	NOUN
aji-178	175	19	and	and	CCONJ
aji-178	175	20	allergenicity	allergenicity	NOUN
aji-178	175	21	.	.	PUNCT
aji-178	176	1	any	any	DET
aji-178	176	2	epitopes	epitope	NOUN
aji-178	176	3	flagged	flag	VERB
aji-178	176	4	as	as	ADP
aji-178	176	5	allergenic	allergenic	NOUN
aji-178	176	6	,	,	PUNCT
aji-178	176	7	toxic	toxic	ADJ
aji-178	176	8	,	,	PUNCT
aji-178	176	9	or	or	CCONJ
aji-178	176	10	nonantigenic	nonantigenic	ADJ
aji-178	176	11	by	by	ADP
aji-178	176	12	allertop	allertop	ADP
aji-178	176	13	v2.0	v2.0	PROPN
aji-178	176	14	,	,	PUNCT
aji-178	176	15	toxinpred	toxinpre	VERB
aji-178	176	16	,	,	PUNCT
aji-178	176	17	or	or	CCONJ
aji-178	176	18	vaxijen	vaxijen	NOUN
aji-178	176	19	were	be	AUX
aji-178	176	20	not	not	PART
aji-178	176	21	included	include	VERB
aji-178	176	22	in	in	ADP
aji-178	176	23	the	the	DET
aji-178	176	24	study	study	NOUN
aji-178	176	25	.	.	PUNCT
aji-178	177	1	altogether	altogether	ADV
aji-178	177	2	,	,	PUNCT
aji-178	177	3	fourteen	fourteen	NUM
aji-178	177	4	b	b	X
aji-178	177	5	-	-	PUNCT
aji-178	177	6	cell	cell	NOUN
aji-178	177	7	epitopes	epitope	NOUN
aji-178	177	8	were	be	AUX
aji-178	177	9	chosen	choose	VERB
aji-178	177	10	from	from	ADP
aji-178	177	11	the	the	DET
aji-178	177	12	ten	ten	NUM
aji-178	177	13	selected	select	VERB
aji-178	177	14	proteins	protein	NOUN
aji-178	177	15	(	(	PUNCT
aji-178	177	16	supplementary	supplementary	ADJ
aji-178	177	17	table	table	NOUN
aji-178	177	18	1	1	NUM
aji-178	177	19	)	)	PUNCT
aji-178	177	20	.	.	PUNCT
aji-178	178	1	4	4	X
aji-178	178	2	.	.	X
aji-178	178	3	ifn	ifn	PROPN
aji-178	178	4	-	-	PUNCT
aji-178	178	5	γ	γ	NOUN
aji-178	178	6	analysis	analysis	NOUN
aji-178	178	7	:	:	PUNCT
aji-178	178	8	ifn	ifn	PROPN
aji-178	178	9	-	-	PUNCT
aji-178	178	10	γ	γ	PROPN
aji-178	178	11	plays	play	VERB
aji-178	178	12	a	a	DET
aji-178	178	13	central	central	ADJ
aji-178	178	14	role	role	NOUN
aji-178	178	15	in	in	ADP
aji-178	178	16	defending	defend	VERB
aji-178	178	17	the	the	DET
aji-178	178	18	body	body	NOUN
aji-178	178	19	against	against	ADP
aji-178	178	20	intracellular	intracellular	ADJ
aji-178	178	21	pathogens	pathogen	NOUN
aji-178	178	22	,	,	PUNCT
aji-178	178	23	and	and	CCONJ
aji-178	178	24	in	in	ADP
aji-178	178	25	mycobacterium	mycobacterium	NOUN
aji-178	178	26	tuberculosis	tuberculosis	NOUN
aji-178	178	27	infection	infection	NOUN
aji-178	178	28	it	it	PRON
aji-178	178	29	is	be	AUX
aji-178	178	30	especially	especially	ADV
aji-178	178	31	important	important	ADJ
aji-178	178	32	for	for	ADP
aji-178	178	33	activating	activate	VERB
aji-178	178	34	macrophages	macrophage	NOUN
aji-178	178	35	(	(	PUNCT
aji-178	178	36	dimitrov	dimitrov	X
aji-178	178	37	et	et	PROPN
aji-178	178	38	al	al	PROPN
aji-178	178	39	.	.	PROPN
aji-178	178	40	,	,	PUNCT
aji-178	178	41	2014	2014	NUM
aji-178	178	42	)	)	PUNCT
aji-178	178	43	.	.	PUNCT
aji-178	179	1	the	the	DET
aji-178	179	2	ifn	ifn	PROPN
aji-178	179	3	were	be	AUX
aji-178	179	4	predicted	predict	VERB
aji-178	179	5	from	from	ADP
aji-178	179	6	the	the	DET
aji-178	179	7	ifn	ifn	PROPN
aji-178	179	8	epitope	epitope	PROPN
aji-178	179	9	server	server	NOUN
aji-178	179	10	(	(	PUNCT
aji-178	179	11	http://crdd.osdd.net/raghava/ifnepitope/	http://crdd.osdd.net/raghava/ifnepitope/	PROPN
aji-178	179	12	)	)	PUNCT
aji-178	179	13	.	.	PUNCT
aji-178	180	1	here	here	ADV
aji-178	180	2	,	,	PUNCT
aji-178	180	3	we	we	PRON
aji-178	180	4	analyzed	analyze	VERB
aji-178	180	5	ifn	ifn	PROPN
aji-178	180	6	-	-	PUNCT
aji-178	180	7	γ	γ	NOUN
aji-178	180	8	activity	activity	NOUN
aji-178	180	9	for	for	ADP
aji-178	180	10	all	all	DET
aji-178	180	11	the	the	DET
aji-178	180	12	selected	select	VERB
aji-178	180	13	epitopes	epitope	NOUN
aji-178	180	14	.	.	PUNCT
aji-178	181	1	5	5	X
aji-178	181	2	.	.	X
aji-178	181	3	vaccine	vaccine	NOUN
aji-178	181	4	construct	construct	VERB
aji-178	181	5	preparation	preparation	NOUN
aji-178	181	6	:	:	PUNCT
aji-178	181	7	five	five	NUM
aji-178	181	8	vaccine	vaccine	NOUN
aji-178	181	9	constructs	construct	NOUN
aji-178	181	10	were	be	AUX
aji-178	181	11	randomly	randomly	ADV
aji-178	181	12	designed	design	VERB
aji-178	181	13	using	use	VERB
aji-178	181	14	the	the	DET
aji-178	181	15	adjuvant	adjuvant	NOUN
aji-178	181	16	(	(	PUNCT
aji-178	181	17	rpfe	rpfe	PROPN
aji-178	181	18	)	)	PUNCT
aji-178	181	19	,	,	PUNCT
aji-178	181	20	which	which	PRON
aji-178	181	21	was	be	AUX
aji-178	181	22	attached	attach	VERB
aji-178	181	23	to	to	ADP
aji-178	181	24	the	the	DET
aji-178	181	25	n	n	CCONJ
aji-178	181	26	-	-	PUNCT
aji-178	181	27	terminal	terminal	ADJ
aji-178	181	28	end	end	NOUN
aji-178	181	29	.	.	PUNCT
aji-178	182	1	each	each	DET
aji-178	182	2	construct	construct	NOUN
aji-178	182	3	followed	follow	VERB
aji-178	182	4	the	the	DET
aji-178	182	5	same	same	ADJ
aji-178	182	6	layout	layout	NOUN
aji-178	182	7	,	,	PUNCT
aji-178	182	8	placing	place	VERB
aji-178	182	9	b	b	NOUN
aji-178	182	10	-	-	PUNCT
aji-178	182	11	cell	cell	NOUN
aji-178	182	12	,	,	PUNCT
aji-178	182	13	htl	htl	PROPN
aji-178	182	14	,	,	PUNCT
aji-178	182	15	ctl	ctl	PROPN
aji-178	182	16	,	,	PUNCT
aji-178	182	17	and	and	CCONJ
aji-178	182	18	then	then	ADV
aji-178	182	19	hla	hla	PROPN
aji-178	182	20	-	-	PUNCT
aji-178	182	21	c	c	NOUN
aji-178	182	22	epitopes	epitope	NOUN
aji-178	182	23	in	in	ADP
aji-178	182	24	sequence	sequence	NOUN
aji-178	182	25	.	.	PUNCT
aji-178	183	1	the	the	DET
aji-178	183	2	epitopes	epitope	NOUN
aji-178	183	3	were	be	AUX
aji-178	183	4	joined	join	VERB
aji-178	183	5	using	use	VERB
aji-178	183	6	kk	kk	PROPN
aji-178	183	7	,	,	PUNCT
aji-178	183	8	gpgpg	gpgpg	NOUN
aji-178	183	9	,	,	PUNCT
aji-178	183	10	and	and	CCONJ
aji-178	183	11	aay	aay	PROPN
aji-178	183	12	linkers	linker	NOUN
aji-178	183	13	,	,	PUNCT
aji-178	183	14	and	and	CCONJ
aji-178	183	15	the	the	DET
aji-178	183	16	adjuvant	adjuvant	NOUN
aji-178	183	17	was	be	AUX
aji-178	183	18	added	add	VERB
aji-178	183	19	using	use	VERB
aji-178	183	20	an	an	DET
aji-178	183	21	eaaak	eaaak	NOUN
aji-178	183	22	linker	linker	NOUN
aji-178	183	23	.	.	PUNCT
aji-178	184	1	6	6	NUM
aji-178	184	2	.	.	X
aji-178	184	3	prediction	prediction	NOUN
aji-178	184	4	of	of	ADP
aji-178	184	5	epitope	epitope	PROPN
aji-178	184	6	’s	’s	PART
aji-178	184	7	antigenicity	antigenicity	NOUN
aji-178	184	8	,	,	PUNCT
aji-178	184	9	allergenicity	allergenicity	NOUN
aji-178	184	10	and	and	CCONJ
aji-178	184	11	toxicity	toxicity	NOUN
aji-178	184	12	:	:	PUNCT
aji-178	184	13	five	five	NUM
aji-178	184	14	vaccine	vaccine	NOUN
aji-178	184	15	constructs	construct	NOUN
aji-178	184	16	were	be	AUX
aji-178	184	17	randomly	randomly	ADV
aji-178	184	18	designed	design	VERB
aji-178	184	19	using	use	VERB
aji-178	184	20	the	the	DET
aji-178	184	21	adjuvant	adjuvant	NOUN
aji-178	184	22	rpfe	rpfe	PROPN
aji-178	184	23	,	,	PUNCT
aji-178	184	24	which	which	PRON
aji-178	184	25	was	be	AUX
aji-178	184	26	attached	attach	VERB
aji-178	184	27	to	to	ADP
aji-178	184	28	the	the	DET
aji-178	184	29	n	n	CCONJ
aji-178	184	30	-	-	PUNCT
aji-178	184	31	terminal	terminal	ADJ
aji-178	184	32	end	end	NOUN
aji-178	184	33	.	.	PUNCT
aji-178	185	1	in	in	ADP
aji-178	185	2	each	each	DET
aji-178	185	3	construct	construct	NOUN
aji-178	185	4	,	,	PUNCT
aji-178	185	5	the	the	DET
aji-178	185	6	selected	select	VERB
aji-178	185	7	epitopes	epitope	NOUN
aji-178	185	8	were	be	AUX
aji-178	185	9	arranged	arrange	VERB
aji-178	185	10	in	in	ADP
aji-178	185	11	the	the	DET
aji-178	185	12	order	order	NOUN
aji-178	185	13	of	of	ADP
aji-178	185	14	b	b	NOUN
aji-178	185	15	-	-	PUNCT
aji-178	185	16	cell	cell	NOUN
aji-178	185	17	,	,	PUNCT
aji-178	185	18	htl	htl	PROPN
aji-178	185	19	,	,	PUNCT
aji-178	185	20	ctl	ctl	PROPN
aji-178	185	21	,	,	PUNCT
aji-178	185	22	and	and	CCONJ
aji-178	185	23	hla	hla	PROPN
aji-178	185	24	-	-	PUNCT
aji-178	185	25	c.	c.	NOUN
aji-178	185	26	the	the	DET
aji-178	185	27	b	b	NOUN
aji-178	185	28	-	-	PUNCT
aji-178	185	29	cell	cell	NOUN
aji-178	185	30	,	,	PUNCT
aji-178	185	31	htl	htl	PROPN
aji-178	185	32	,	,	PUNCT
aji-178	185	33	ctl	ctl	PROPN
aji-178	185	34	,	,	PUNCT
aji-178	185	35	and	and	CCONJ
aji-178	185	36	hla	hla	PROPN
aji-178	185	37	-	-	PUNCT
aji-178	185	38	c	c	NOUN
aji-178	185	39	epitopes	epitope	NOUN
aji-178	185	40	were	be	AUX
aji-178	185	41	joined	join	VERB
aji-178	185	42	using	use	VERB
aji-178	185	43	kk	kk	PROPN
aji-178	185	44	,	,	PUNCT
aji-178	185	45	gpgpg	gpgpg	NOUN
aji-178	185	46	,	,	PUNCT
aji-178	185	47	and	and	CCONJ
aji-178	185	48	aay	aay	PROPN
aji-178	185	49	linkers	linker	NOUN
aji-178	185	50	,	,	PUNCT
aji-178	185	51	respectively	respectively	ADV
aji-178	185	52	,	,	PUNCT
aji-178	185	53	while	while	SCONJ
aji-178	185	54	the	the	DET
aji-178	185	55	adjuvant	adjuvant	NOUN
aji-178	185	56	was	be	AUX
aji-178	185	57	connected	connect	VERB
aji-178	185	58	through	through	ADP
aji-178	185	59	an	an	DET
aji-178	185	60	eaaak	eaaak	NOUN
aji-178	185	61	linker	linker	NOUN
aji-178	185	62	,	,	PUNCT
aji-178	185	63	the	the	DET
aji-178	185	64	relative	relative	ADJ
aji-178	185	65	abundance	abundance	NOUN
aji-178	185	66	of	of	ADP
aji-178	185	67	amino	amino	ADJ
aji-178	185	68	acids	acid	NOUN
aji-178	185	69	,	,	PUNCT
aji-178	185	70	and	and	CCONJ
aji-178	185	71	β	β	X
aji-178	185	72	-	-	ADJ
aji-178	185	73	strand	strand	ADJ
aji-178	185	74	forming	form	VERB
aji-178	185	75	propensity	propensity	NOUN
aji-178	185	76	(	(	PUNCT
aji-178	185	77	doytchinova	doytchinova	PROPN
aji-178	185	78	&	&	CCONJ
aji-178	185	79	flower	flower	PROPN
aji-178	185	80	,	,	PUNCT
aji-178	185	81	2007	2007	NUM
aji-178	185	82	)	)	PUNCT
aji-178	185	83	.	.	PUNCT
aji-178	186	1	prediction	prediction	NOUN
aji-178	186	2	of	of	ADP
aji-178	186	3	antigenicity	antigenicity	NOUN
aji-178	186	4	was	be	AUX
aji-178	186	5	done	do	VERB
aji-178	186	6	by	by	ADP
aji-178	186	7	alignment	alignment	NOUN
aji-178	186	8	-	-	PUNCT
aji-178	186	9	independent	independent	ADJ
aji-178	186	10	fashion	fashion	NOUN
aji-178	186	11	based	base	VERB
aji-178	186	12	on	on	ADP
aji-178	186	13	its	its	PRON
aji-178	186	14	physicochemical	physicochemical	ADJ
aji-178	186	15	properties	property	NOUN
aji-178	186	16	using	use	VERB
aji-178	186	17	vaxijen	vaxijen	PROPN
aji-178	186	18	online	online	ADJ
aji-178	186	19	web	web	NOUN
aji-178	186	20	server	server	NOUN
aji-178	186	21	(	(	PUNCT
aji-178	186	22	gupta	gupta	PROPN
aji-178	186	23	et	et	PROPN
aji-178	186	24	al	al	PROPN
aji-178	186	25	.	.	PROPN
aji-178	186	26	,	,	PUNCT
aji-178	186	27	2013	2013	NUM
aji-178	186	28	)	)	PUNCT
aji-178	186	29	.	.	PUNCT
aji-178	187	1	this	this	DET
aji-178	187	2	tool	tool	NOUN
aji-178	187	3	provided	provide	VERB
aji-178	187	4	varied	varied	ADJ
aji-178	187	5	options	option	NOUN
aji-178	187	6	for	for	ADP
aji-178	187	7	the	the	DET
aji-178	187	8	organism	organism	NOUN
aji-178	187	9	selected	select	VERB
aji-178	187	10	for	for	ADP
aji-178	187	11	analysis	analysis	NOUN
aji-178	187	12	was	be	AUX
aji-178	187	13	bacteria	bacteria	NOUN
aji-178	187	14	,	,	PUNCT
aji-178	187	15	for	for	ADP
aji-178	187	16	which	which	PRON
aji-178	187	17	the	the	DET
aji-178	187	18	corresponding	correspond	VERB
aji-178	187	19	default	default	NOUN
aji-178	187	20	threshold	threshold	NOUN
aji-178	187	21	score	score	NOUN
aji-178	187	22	(	(	PUNCT
aji-178	187	23	0.4	0.4	NUM
aji-178	187	24	)	)	PUNCT
aji-178	187	25	was	be	AUX
aji-178	187	26	applied	apply	VERB
aji-178	187	27	automatically	automatically	ADV
aji-178	187	28	.	.	PUNCT
aji-178	188	1	the	the	DET
aji-178	188	2	toxinpred	toxinpre	VERB
aji-178	188	3	server	server	NOUN
aji-178	188	4	was	be	AUX
aji-178	188	5	employed	employ	VERB
aji-178	188	6	to	to	PART
aji-178	188	7	assess	assess	VERB
aji-178	188	8	the	the	DET
aji-178	188	9	toxicity	toxicity	NOUN
aji-178	188	10	of	of	ADP
aji-178	188	11	the	the	DET
aji-178	188	12	selected	select	VERB
aji-178	188	13	sequences	sequence	NOUN
aji-178	188	14	,	,	PUNCT
aji-178	188	15	as	as	SCONJ
aji-178	188	16	this	this	DET
aji-178	188	17	tool	tool	NOUN
aji-178	188	18	generates	generate	VERB
aji-178	188	19	all	all	DET
aji-178	188	20	possible	possible	ADJ
aji-178	188	21	naseema	naseema	NOUN
aji-178	188	22	;	;	PUNCT
aji-178	188	23	asian	asian	ADJ
aji-178	188	24	j.	j.	PROPN
aji-178	188	25	immunol	immunol	PROPN
aji-178	188	26	.	.	PROPN
aji-178	189	1	,	,	PUNCT
aji-178	189	2	vol	vol	NOUN
aji-178	189	3	.	.	PROPN
aji-178	189	4	8	8	NUM
aji-178	189	5	,	,	PUNCT
aji-178	189	6	no	no	INTJ
aji-178	189	7	.	.	NOUN
aji-178	189	8	1	1	NUM
aji-178	189	9	,	,	PUNCT
aji-178	189	10	pp	pp	ADJ
aji-178	189	11	.	.	PUNCT
aji-178	190	1	269	269	NUM
aji-178	190	2	-	-	SYM
aji-178	190	3	284	284	NUM
aji-178	190	4	,	,	PUNCT
aji-178	190	5	2025	2025	NUM
aji-178	190	6	;	;	PUNCT
aji-178	190	7	article	article	NOUN
aji-178	190	8	no.aji.147582	no.aji.147582	VERB
aji-178	190	9	272	272	NUM
aji-178	190	10	mutants	mutant	NOUN
aji-178	190	11	of	of	ADP
aji-178	190	12	the	the	DET
aji-178	190	13	input	input	NOUN
aji-178	190	14	peptides	peptide	NOUN
aji-178	190	15	for	for	ADP
aji-178	190	16	evaluation	evaluation	NOUN
aji-178	190	17	(	(	PUNCT
aji-178	190	18	branger	branger	NOUN
aji-178	190	19	et	et	PROPN
aji-178	190	20	al	al	PROPN
aji-178	190	21	.	.	PROPN
aji-178	190	22	,	,	PUNCT
aji-178	190	23	2004	2004	NUM
aji-178	190	24	)	)	PUNCT
aji-178	190	25	.	.	PUNCT
aji-178	191	1	all	all	DET
aji-178	191	2	parameters	parameter	NOUN
aji-178	191	3	in	in	ADP
aji-178	191	4	both	both	PRON
aji-178	191	5	allertop	allertop	NOUN
aji-178	191	6	v.2.0	v.2.0	PROPN
aji-178	191	7	and	and	CCONJ
aji-178	191	8	toxinpred	toxinpre	VERB
aji-178	191	9	were	be	AUX
aji-178	191	10	maintained	maintain	VERB
aji-178	191	11	at	at	ADP
aji-178	191	12	their	their	PRON
aji-178	191	13	default	default	NOUN
aji-178	191	14	settings	setting	NOUN
aji-178	191	15	.	.	PUNCT
aji-178	192	1	7	7	X
aji-178	192	2	.	.	X
aji-178	192	3	homology	homology	NOUN
aji-178	192	4	modelling	modelling	NOUN
aji-178	192	5	of	of	ADP
aji-178	192	6	vaccine	vaccine	NOUN
aji-178	192	7	constructs	construct	VERB
aji-178	192	8	:	:	PUNCT
aji-178	192	9	the	the	DET
aji-178	192	10	five	five	NUM
aji-178	192	11	vaccine	vaccine	NOUN
aji-178	192	12	constructs	construct	NOUN
aji-178	192	13	were	be	AUX
aji-178	192	14	analyzed	analyze	VERB
aji-178	192	15	through	through	ADP
aji-178	192	16	homology	homology	NOUN
aji-178	192	17	modelling	modelling	NOUN
aji-178	192	18	on	on	ADP
aji-178	192	19	the	the	DET
aji-178	192	20	swissmodel	swissmodel	PROPN
aji-178	192	21	server	server	NOUN
aji-178	192	22	to	to	PART
aji-178	192	23	identify	identify	VERB
aji-178	192	24	the	the	DET
aji-178	192	25	most	most	ADV
aji-178	192	26	structurally	structurally	ADV
aji-178	192	27	stable	stable	ADJ
aji-178	192	28	option	option	NOUN
aji-178	192	29	.	.	PUNCT
aji-178	193	1	the	the	DET
aji-178	193	2	generated	generate	VERB
aji-178	193	3	models	model	NOUN
aji-178	193	4	were	be	AUX
aji-178	193	5	saved	save	VERB
aji-178	193	6	in	in	ADP
aji-178	193	7	pdb	pdb	PROPN
aji-178	193	8	format	format	NOUN
aji-178	193	9	for	for	ADP
aji-178	193	10	later	later	ADJ
aji-178	193	11	evaluation	evaluation	NOUN
aji-178	193	12	.	.	PUNCT
aji-178	194	1	8	8	X
aji-178	194	2	.	.	X
aji-178	194	3	structure	structure	NOUN
aji-178	194	4	refinement	refinement	NOUN
aji-178	194	5	of	of	ADP
aji-178	194	6	vaccine	vaccine	NOUN
aji-178	194	7	construct	construct	VERB
aji-178	194	8	:	:	PUNCT
aji-178	194	9	the	the	DET
aji-178	194	10	tertiary	tertiary	ADJ
aji-178	194	11	structure	structure	NOUN
aji-178	194	12	of	of	ADP
aji-178	194	13	the	the	DET
aji-178	194	14	selected	select	VERB
aji-178	194	15	vaccine	vaccine	NOUN
aji-178	194	16	draft	draft	NOUN
aji-178	194	17	was	be	AUX
aji-178	194	18	refined	refine	VERB
aji-178	194	19	utilizing	utilize	VERB
aji-178	194	20	the	the	DET
aji-178	194	21	castp	castp	ADJ
aji-178	194	22	web	web	NOUN
aji-178	194	23	server	server	NOUN
aji-178	194	24	.	.	PUNCT
aji-178	195	1	castp	castp	PROPN
aji-178	195	2	applies	apply	VERB
aji-178	195	3	structural	structural	ADJ
aji-178	195	4	perturbation	perturbation	NOUN
aji-178	195	5	and	and	CCONJ
aji-178	195	6	molecular	molecular	ADJ
aji-178	195	7	dynamics	dynamic	NOUN
aji-178	195	8	simulations	simulation	NOUN
aji-178	195	9	to	to	PART
aji-178	195	10	achieve	achieve	VERB
aji-178	195	11	protein	protein	NOUN
aji-178	195	12	relaxation	relaxation	NOUN
aji-178	195	13	.	.	PUNCT
aji-178	196	1	the	the	DET
aji-178	196	2	most	most	ADV
aji-178	196	3	stable	stable	ADJ
aji-178	196	4	and	and	CCONJ
aji-178	196	5	accurately	accurately	ADV
aji-178	196	6	refined	refined	ADJ
aji-178	196	7	model	model	NOUN
aji-178	196	8	was	be	AUX
aji-178	196	9	selected	select	VERB
aji-178	196	10	for	for	ADP
aji-178	196	11	further	further	ADJ
aji-178	196	12	evaluation	evaluation	NOUN
aji-178	196	13	,	,	PUNCT
aji-178	196	14	including	include	VERB
aji-178	196	15	physicochemical	physicochemical	ADJ
aji-178	196	16	property	property	NOUN
aji-178	196	17	assessment	assessment	NOUN
aji-178	196	18	and	and	CCONJ
aji-178	196	19	molecular	molecular	ADJ
aji-178	196	20	docking	docking	NOUN
aji-178	196	21	studies	study	NOUN
aji-178	196	22	.	.	PUNCT
aji-178	197	1	9	9	X
aji-178	197	2	.	.	X
aji-178	197	3	physiochemical	physiochemical	ADJ
aji-178	197	4	properties	property	NOUN
aji-178	197	5	of	of	ADP
aji-178	197	6	vaccine	vaccine	NOUN
aji-178	197	7	construct	construct	VERB
aji-178	197	8	:	:	PUNCT
aji-178	197	9	the	the	DET
aji-178	197	10	physicochemical	physicochemical	ADJ
aji-178	197	11	characteristics	characteristic	NOUN
aji-178	197	12	of	of	ADP
aji-178	197	13	the	the	DET
aji-178	197	14	vaccine	vaccine	NOUN
aji-178	197	15	construct	construct	NOUN
aji-178	197	16	were	be	AUX
aji-178	197	17	found	find	VERB
aji-178	197	18	using	use	VERB
aji-178	197	19	the	the	DET
aji-178	197	20	protparam	protparam	PROPN
aji-178	197	21	tool	tool	NOUN
aji-178	197	22	available	available	ADJ
aji-178	197	23	online	online	ADV
aji-178	197	24	.	.	PUNCT
aji-178	198	1	this	this	DET
aji-178	198	2	tool	tool	NOUN
aji-178	198	3	evaluates	evaluate	VERB
aji-178	198	4	several	several	ADJ
aji-178	198	5	properties	property	NOUN
aji-178	198	6	of	of	ADP
aji-178	198	7	a	a	DET
aji-178	198	8	protein	protein	NOUN
aji-178	198	9	,	,	PUNCT
aji-178	198	10	including	include	VERB
aji-178	198	11	molecular	molecular	ADJ
aji-178	198	12	weight	weight	NOUN
aji-178	198	13	,	,	PUNCT
aji-178	198	14	theoretical	theoretical	ADJ
aji-178	198	15	isoelectric	isoelectric	ADJ
aji-178	198	16	point	point	NOUN
aji-178	198	17	(	(	PUNCT
aji-178	198	18	pi	pi	NOUN
aji-178	198	19	)	)	PUNCT
aji-178	198	20	,	,	PUNCT
aji-178	198	21	instability	instability	NOUN
aji-178	198	22	index	index	NOUN
aji-178	198	23	,	,	PUNCT
aji-178	198	24	protein	protein	NOUN
aji-178	198	25	length	length	NOUN
aji-178	198	26	,	,	PUNCT
aji-178	198	27	estimated	estimate	VERB
aji-178	198	28	half	half	ADJ
aji-178	198	29	life	life	NOUN
aji-178	198	30	,	,	PUNCT
aji-178	198	31	aliphatic	aliphatic	ADJ
aji-178	198	32	index	index	NOUN
aji-178	198	33	,	,	PUNCT
aji-178	198	34	and	and	CCONJ
aji-178	198	35	the	the	DET
aji-178	198	36	grand	grand	ADJ
aji-178	198	37	average	average	NOUN
aji-178	198	38	of	of	ADP
aji-178	198	39	hydropathicity	hydropathicity	NOUN
aji-178	198	40	(	(	PUNCT
aji-178	198	41	gravy	gravy	PROPN
aji-178	198	42	)	)	PUNCT
aji-178	198	43	.	.	PUNCT
aji-178	199	1	10	10	X
aji-178	199	2	.	.	X
aji-178	199	3	molecular	molecular	ADJ
aji-178	199	4	docking	docking	NOUN
aji-178	199	5	of	of	ADP
aji-178	199	6	vaccine	vaccine	NOUN
aji-178	199	7	construct	construct	VERB
aji-178	199	8	:	:	PUNCT
aji-178	199	9	the	the	DET
aji-178	199	10	refined	refined	ADJ
aji-178	199	11	3d	3d	PROPN
aji-178	199	12	structures	structure	NOUN
aji-178	199	13	of	of	ADP
aji-178	199	14	the	the	DET
aji-178	199	15	vaccine	vaccine	NOUN
aji-178	199	16	constructs	construct	NOUN
aji-178	199	17	were	be	AUX
aji-178	199	18	utilized	utilize	VERB
aji-178	199	19	for	for	ADP
aji-178	199	20	molecular	molecular	ADJ
aji-178	199	21	docking	docking	NOUN
aji-178	199	22	studies	study	NOUN
aji-178	199	23	.	.	PUNCT
aji-178	200	1	the	the	DET
aji-178	200	2	crystal	crystal	NOUN
aji-178	200	3	structure	structure	NOUN
aji-178	200	4	of	of	ADP
aji-178	200	5	the	the	DET
aji-178	200	6	human	human	ADJ
aji-178	200	7	tlr4	tlr4	NOUN
aji-178	200	8	receptor	receptor	NOUN
aji-178	200	9	complex	complex	NOUN
aji-178	200	10	(	(	PUNCT
aji-178	200	11	pdb	pdb	PROPN
aji-178	200	12	i	i	PROPN
aji-178	200	13	d	d	PROPN
aji-178	200	14	:	:	PUNCT
aji-178	200	15	3fxi	3fxi	NUM
aji-178	200	16	)	)	PUNCT
aji-178	200	17	was	be	AUX
aji-178	200	18	retrieved	retrieve	VERB
aji-178	200	19	from	from	ADP
aji-178	200	20	the	the	DET
aji-178	200	21	protein	protein	NOUN
aji-178	200	22	data	datum	NOUN
aji-178	200	23	bank	bank	NOUN
aji-178	200	24	.	.	PUNCT
aji-178	201	1	docking	docking	NOUN
aji-178	201	2	was	be	AUX
aji-178	201	3	performed	perform	VERB
aji-178	201	4	using	use	VERB
aji-178	201	5	the	the	DET
aji-178	201	6	pydock	pydock	NOUN
aji-178	201	7	web	web	NOUN
aji-178	201	8	server	server	NOUN
aji-178	201	9	with	with	ADP
aji-178	201	10	the	the	DET
aji-178	201	11	monomeric	monomeric	ADJ
aji-178	201	12	form	form	NOUN
aji-178	201	13	of	of	ADP
aji-178	201	14	the	the	DET
aji-178	201	15	human	human	ADJ
aji-178	201	16	tlr4	tlr4	NOUN
aji-178	201	17	receptor	receptor	NOUN
aji-178	201	18	(	(	PUNCT
aji-178	201	19	schorey	schorey	PROPN
aji-178	201	20	&	&	CCONJ
aji-178	201	21	harding	harding	PROPN
aji-178	201	22	,	,	PUNCT
aji-178	201	23	2016	2016	NUM
aji-178	201	24	)	)	PUNCT
aji-178	201	25	.	.	PUNCT
aji-178	202	1	additionally	additionally	ADV
aji-178	202	2	,	,	PUNCT
aji-178	202	3	autodock	autodock	NOUN
aji-178	202	4	vina	vina	NOUN
aji-178	202	5	was	be	AUX
aji-178	202	6	employed	employ	VERB
aji-178	202	7	to	to	PART
aji-178	202	8	perform	perform	VERB
aji-178	202	9	docking	docking	NOUN
aji-178	202	10	using	use	VERB
aji-178	202	11	the	the	DET
aji-178	202	12	a	a	PRON
aji-178	202	13	-	-	PUNCT
aji-178	202	14	chain	chain	NOUN
aji-178	202	15	of	of	ADP
aji-178	202	16	the	the	DET
aji-178	202	17	tlr4	tlr4	NOUN
aji-178	202	18	crystal	crystal	NOUN
aji-178	202	19	structure	structure	NOUN
aji-178	202	20	with	with	ADP
aji-178	202	21	the	the	DET
aji-178	202	22	vaccine	vaccine	NOUN
aji-178	202	23	constructs	construct	VERB
aji-178	202	24	(	(	PUNCT
aji-178	202	25	park	park	NOUN
aji-178	202	26	et	et	PROPN
aji-178	202	27	al	al	PROPN
aji-178	202	28	.	.	PROPN
aji-178	202	29	,	,	PUNCT
aji-178	202	30	2009	2009	NUM
aji-178	202	31	;	;	PUNCT
aji-178	202	32	heo	heo	PROPN
aji-178	202	33	et	et	PROPN
aji-178	202	34	al	al	PROPN
aji-178	202	35	.	.	PROPN
aji-178	202	36	,	,	PUNCT
aji-178	202	37	2013	2013	NUM
aji-178	202	38	)	)	PUNCT
aji-178	202	39	.	.	PUNCT
aji-178	203	1	using	use	VERB
aji-178	203	2	the	the	DET
aji-178	203	3	castp	castp	ADJ
aji-178	203	4	server	server	NOUN
aji-178	203	5	,	,	PUNCT
aji-178	203	6	we	we	PRON
aji-178	203	7	identified	identify	VERB
aji-178	203	8	the	the	DET
aji-178	203	9	active	active	ADJ
aji-178	203	10	and	and	CCONJ
aji-178	203	11	passive	passive	ADJ
aji-178	203	12	binding	bind	VERB
aji-178	203	13	pockets	pocket	NOUN
aji-178	203	14	of	of	ADP
aji-178	203	15	the	the	DET
aji-178	203	16	tlr4	tlr4	NOUN
aji-178	203	17	receptor	receptor	NOUN
aji-178	203	18	and	and	CCONJ
aji-178	203	19	the	the	DET
aji-178	203	20	refined	refined	ADJ
aji-178	203	21	vaccine	vaccine	NOUN
aji-178	203	22	constructs	construct	VERB
aji-178	203	23	.	.	PUNCT
aji-178	204	1	the	the	DET
aji-178	204	2	corresponding	correspond	VERB
aji-178	204	3	pdb	pdb	NOUN
aji-178	204	4	files	file	NOUN
aji-178	204	5	were	be	AUX
aji-178	204	6	then	then	ADV
aji-178	204	7	uploaded	upload	VERB
aji-178	204	8	to	to	ADP
aji-178	204	9	the	the	DET
aji-178	204	10	pydock	pydock	NOUN
aji-178	204	11	server	server	NOUN
aji-178	204	12	for	for	ADP
aji-178	204	13	docking	dock	VERB
aji-178	204	14	analysis	analysis	NOUN
aji-178	204	15	.	.	PUNCT
aji-178	205	1	fig	fig	NOUN
aji-178	205	2	.	.	PUNCT
aji-178	206	1	1	1	X
aji-178	206	2	.	.	PUNCT
aji-178	206	3	the	the	DET
aji-178	206	4	schematic	schematic	ADJ
aji-178	206	5	illustration	illustration	NOUN
aji-178	206	6	of	of	ADP
aji-178	206	7	the	the	DET
aji-178	206	8	final	final	ADJ
aji-178	206	9	vaccine	vaccine	NOUN
aji-178	206	10	construct	construct	VERB
aji-178	206	11	shows	show	VERB
aji-178	206	12	the	the	DET
aji-178	206	13	arrangement	arrangement	NOUN
aji-178	206	14	of	of	ADP
aji-178	206	15	epitopes	epitope	NOUN
aji-178	206	16	,	,	PUNCT
aji-178	206	17	represented	represent	VERB
aji-178	206	18	within	within	ADP
aji-178	206	19	colored	colored	ADJ
aji-178	206	20	boxes	box	NOUN
aji-178	206	21	and	and	CCONJ
aji-178	206	22	connected	connect	VERB
aji-178	206	23	by	by	ADP
aji-178	206	24	linker	linker	NOUN
aji-178	206	25	sequences	sequence	NOUN
aji-178	206	26	.	.	PUNCT
aji-178	207	1	the	the	DET
aji-178	207	2	designed	design	VERB
aji-178	207	3	construct	construct	NOUN
aji-178	207	4	is	be	AUX
aji-178	207	5	made	make	VERB
aji-178	207	6	up	up	ADP
aji-178	207	7	of	of	ADP
aji-178	207	8	623	623	NUM
aji-178	207	9	amino	amino	NOUN
aji-178	207	10	acids	acid	NOUN
aji-178	207	11	,	,	PUNCT
aji-178	207	12	including	include	VERB
aji-178	207	13	a	a	DET
aji-178	207	14	172	172	NUM
aji-178	207	15	-	-	PUNCT
aji-178	207	16	amino	amino	NOUN
aji-178	207	17	-	-	PUNCT
aji-178	207	18	acid	acid	NOUN
aji-178	207	19	adjuvant	adjuvant	NOUN
aji-178	207	20	(	(	PUNCT
aji-178	207	21	rpfe	rpfe	VERB
aji-178	207	22	/	/	SYM
aji-178	207	23	rv2450c	rv2450c	NOUN
aji-178	207	24	)	)	PUNCT
aji-178	207	25	highlighted	highlight	VERB
aji-178	207	26	in	in	ADP
aji-178	207	27	yellow	yellow	ADJ
aji-178	207	28	.	.	PUNCT
aji-178	208	1	it	it	PRON
aji-178	208	2	incorporates	incorporate	VERB
aji-178	208	3	14	14	NUM
aji-178	208	4	b	b	NUM
aji-178	208	5	-	-	PUNCT
aji-178	208	6	cell	cell	NOUN
aji-178	208	7	epitopes	epitope	NOUN
aji-178	208	8	(	(	PUNCT
aji-178	208	9	blue	blue	ADJ
aji-178	208	10	)	)	PUNCT
aji-178	208	11	,	,	PUNCT
aji-178	208	12	5	5	NUM
aji-178	208	13	htl	htl	PROPN
aji-178	208	14	epitopes	epitope	NOUN
aji-178	208	15	(	(	PUNCT
aji-178	208	16	orange	orange	PROPN
aji-178	208	17	)	)	PUNCT
aji-178	208	18	,	,	PUNCT
aji-178	208	19	5	5	NUM
aji-178	208	20	ctl	ctl	PROPN
aji-178	208	21	epitopes	epitope	NOUN
aji-178	208	22	(	(	PUNCT
aji-178	208	23	green	green	ADJ
aji-178	208	24	)	)	PUNCT
aji-178	208	25	,	,	PUNCT
aji-178	208	26	and	and	CCONJ
aji-178	208	27	3	3	NUM
aji-178	208	28	hla	hla	NOUN
aji-178	208	29	-	-	PUNCT
aji-178	208	30	c	c	NOUN
aji-178	208	31	epitopes	epitope	NOUN
aji-178	208	32	(	(	PUNCT
aji-178	208	33	pink	pink	ADJ
aji-178	208	34	)	)	PUNCT
aji-178	208	35	.	.	PUNCT
aji-178	209	1	an	an	DET
aji-178	209	2	eaaak	eaaak	NOUN
aji-178	209	3	linker	linker	NOUN
aji-178	209	4	attaches	attach	VERB
aji-178	209	5	the	the	DET
aji-178	209	6	adjuvant	adjuvant	NOUN
aji-178	209	7	to	to	ADP
aji-178	209	8	the	the	DET
aji-178	209	9	nterminus	nterminus	NOUN
aji-178	209	10	,	,	PUNCT
aji-178	209	11	while	while	SCONJ
aji-178	209	12	the	the	DET
aji-178	209	13	b	b	NOUN
aji-178	209	14	-	-	PUNCT
aji-178	209	15	cell	cell	NOUN
aji-178	209	16	,	,	PUNCT
aji-178	209	17	htl	htl	PROPN
aji-178	209	18	,	,	PUNCT
aji-178	209	19	ctl	ctl	PROPN
aji-178	209	20	,	,	PUNCT
aji-178	209	21	and	and	CCONJ
aji-178	209	22	hla	hla	PROPN
aji-178	209	23	-	-	PUNCT
aji-178	209	24	c	c	NOUN
aji-178	209	25	epitopes	epitope	NOUN
aji-178	209	26	are	be	AUX
aji-178	209	27	connected	connect	VERB
aji-178	209	28	using	use	VERB
aji-178	209	29	kk	kk	PROPN
aji-178	209	30	,	,	PUNCT
aji-178	209	31	gpgpg	gpgpg	NOUN
aji-178	209	32	,	,	PUNCT
aji-178	209	33	and	and	CCONJ
aji-178	209	34	aay	aay	PROPN
aji-178	209	35	linkers	linker	NOUN
aji-178	209	36	naseema	naseema	VERB
aji-178	209	37	;	;	PUNCT
aji-178	209	38	asian	asian	ADJ
aji-178	209	39	j.	j.	PROPN
aji-178	209	40	immunol	immunol	PROPN
aji-178	209	41	.	.	PROPN
aji-178	209	42	,	,	PUNCT
aji-178	209	43	vol	vol	NOUN
aji-178	209	44	.	.	PROPN
aji-178	209	45	8	8	NUM
aji-178	209	46	,	,	PUNCT
aji-178	209	47	no	no	INTJ
aji-178	209	48	.	.	NOUN
aji-178	209	49	1	1	NUM
aji-178	209	50	,	,	PUNCT
aji-178	209	51	pp	pp	ADJ
aji-178	209	52	.	.	PUNCT
aji-178	210	1	269	269	NUM
aji-178	210	2	-	-	SYM
aji-178	210	3	284	284	NUM
aji-178	210	4	,	,	PUNCT
aji-178	210	5	2025	2025	NUM
aji-178	210	6	;	;	PUNCT
aji-178	210	7	article	article	NOUN
aji-178	210	8	no.aji.147582	no.aji.147582	VERB
aji-178	210	9	273	273	NUM
aji-178	210	10	a	a	DET
aji-178	210	11	)	)	PUNCT
aji-178	210	12	b	b	NOUN
aji-178	210	13	)	)	PUNCT
aji-178	210	14	fig	fig	NOUN
aji-178	210	15	.	.	PUNCT
aji-178	211	1	2	2	X
aji-178	211	2	.	.	X
aji-178	211	3	vaccine	vaccine	NOUN
aji-178	211	4	construct	construct	VERB
aji-178	211	5	homology	homology	NOUN
aji-178	211	6	modelling	modelling	NOUN
aji-178	211	7	and	and	CCONJ
aji-178	211	8	structural	structural	ADJ
aji-178	211	9	refinement	refinement	NOUN
aji-178	211	10	:	:	PUNCT
aji-178	211	11	(	(	PUNCT
aji-178	211	12	a	a	X
aji-178	211	13	)	)	PUNCT
aji-178	211	14	the	the	DET
aji-178	211	15	rpfe	rpfe	ADJ
aji-178	211	16	vaccine	vaccine	NOUN
aji-178	211	17	construct	construct	VERB
aji-178	211	18	’s	’s	ADJ
aji-178	211	19	three	three	NUM
aji-178	211	20	-	-	PUNCT
aji-178	211	21	dimensional	dimensional	ADJ
aji-178	211	22	structure	structure	NOUN
aji-178	211	23	was	be	AUX
aji-178	211	24	first	first	ADV
aji-178	211	25	created	create	VERB
aji-178	211	26	using	use	VERB
aji-178	211	27	swiss	swiss	ADJ
aji-178	211	28	-	-	PUNCT
aji-178	211	29	model	model	NOUN
aji-178	211	30	(	(	PUNCT
aji-178	211	31	b	b	NOUN
aji-178	211	32	)	)	PUNCT
aji-178	211	33	refined	refined	ADJ
aji-178	211	34	version	version	NOUN
aji-178	211	35	was	be	AUX
aji-178	211	36	produced	produce	VERB
aji-178	211	37	using	use	VERB
aji-178	211	38	castp	castp	NOUN
aji-178	211	39	(	(	PUNCT
aji-178	211	40	binkowski	binkowski	NOUN
aji-178	211	41	et	et	PROPN
aji-178	211	42	al	al	PROPN
aji-178	211	43	.	.	PROPN
aji-178	211	44	,	,	PUNCT
aji-178	211	45	2003	2003	NUM
aji-178	211	46	)	)	PUNCT
aji-178	211	47	11	11	NUM
aji-178	211	48	.	.	PUNCT
aji-178	211	49	immune	immune	ADJ
aji-178	211	50	simulation	simulation	NOUN
aji-178	211	51	for	for	ADP
aji-178	211	52	vaccine	vaccine	NOUN
aji-178	211	53	efficacy	efficacy	NOUN
aji-178	211	54	“	"	PUNCT
aji-178	211	55	c	c	NOUN
aji-178	211	56	-	-	PUNCT
aji-178	211	57	immsim	immsim	NOUN
aji-178	211	58	was	be	AUX
aji-178	211	59	used	use	VERB
aji-178	211	60	to	to	PART
aji-178	211	61	assess	assess	VERB
aji-178	211	62	the	the	DET
aji-178	211	63	immune	immune	ADJ
aji-178	211	64	response	response	NOUN
aji-178	211	65	and	and	CCONJ
aji-178	211	66	immunogenicity	immunogenicity	NOUN
aji-178	211	67	of	of	ADP
aji-178	211	68	the	the	DET
aji-178	211	69	multiepitope	multiepitope	NOUN
aji-178	211	70	vaccine	vaccine	NOUN
aji-178	211	71	.	.	PUNCT
aji-178	212	1	the	the	DET
aji-178	212	2	server	server	NOUN
aji-178	212	3	applies	apply	VERB
aji-178	212	4	a	a	DET
aji-178	212	5	positionspecific	positionspecific	NOUN
aji-178	212	6	scoring	scoring	NOUN
aji-178	212	7	matrix	matrix	NOUN
aji-178	212	8	and	and	CCONJ
aji-178	212	9	machine	machine	NOUN
aji-178	212	10	learning	learning	NOUN
aji-178	212	11	,	,	PUNCT
aji-178	212	12	along	along	ADP
aji-178	212	13	with	with	ADP
aji-178	212	14	epitope	epitope	NOUN
aji-178	212	15	prediction	prediction	NOUN
aji-178	212	16	,	,	PUNCT
aji-178	212	17	to	to	PART
aji-178	212	18	model	model	VERB
aji-178	212	19	immune	immune	ADJ
aji-178	212	20	interactions	interaction	NOUN
aji-178	212	21	.	.	PUNCT
aji-178	213	1	it	it	PRON
aji-178	213	2	contains	contain	VERB
aji-178	213	3	6,533	6,533	NUM
aji-178	213	4	antigenic	antigenic	ADJ
aji-178	213	5	epitopes	epitope	NOUN
aji-178	213	6	and	and	CCONJ
aji-178	213	7	33	33	NUM
aji-178	213	8	different	different	ADJ
aji-178	213	9	human	human	PROPN
aji-178	213	10	hla	hla	PROPN
aji-178	213	11	allele	allele	NOUN
aji-178	213	12	sets	set	NOUN
aji-178	213	13	,	,	PUNCT
aji-178	213	14	simulating	simulate	VERB
aji-178	213	15	responses	response	NOUN
aji-178	213	16	by	by	ADP
aji-178	213	17	pairing	pair	VERB
aji-178	213	18	epitope	epitope	NOUN
aji-178	213	19	sequences	sequence	NOUN
aji-178	213	20	with	with	ADP
aji-178	213	21	lymphocyte	lymphocyte	ADJ
aji-178	213	22	receptors	receptor	NOUN
aji-178	213	23	”	"	PUNCT
aji-178	213	24	(	(	PUNCT
aji-178	213	25	brosch	brosch	PROPN
aji-178	213	26	et	et	PROPN
aji-178	213	27	al	al	PROPN
aji-178	213	28	.	.	PROPN
aji-178	213	29	,	,	PUNCT
aji-178	213	30	2007	2007	NUM
aji-178	213	31	)	)	PUNCT
aji-178	213	32	.	.	PUNCT
aji-178	214	1	“	"	PUNCT
aji-178	214	2	the	the	DET
aji-178	214	3	tool	tool	NOUN
aji-178	214	4	predicts	predict	VERB
aji-178	214	5	immune	immune	ADJ
aji-178	214	6	responses	response	NOUN
aji-178	214	7	by	by	ADP
aji-178	214	8	simulating	simulate	VERB
aji-178	214	9	three	three	NUM
aji-178	214	10	important	important	ADJ
aji-178	214	11	mammalian	mammalian	ADJ
aji-178	214	12	anatomical	anatomical	ADJ
aji-178	214	13	regions	region	NOUN
aji-178	214	14	:	:	PUNCT
aji-178	214	15	the	the	DET
aji-178	214	16	thymus	thymus	NOUN
aji-178	214	17	,	,	PUNCT
aji-178	214	18	bone	bone	NOUN
aji-178	214	19	marrow	marrow	NOUN
aji-178	214	20	,	,	PUNCT
aji-178	214	21	and	and	CCONJ
aji-178	214	22	a	a	DET
aji-178	214	23	tertiary	tertiary	ADJ
aji-178	214	24	lymphoid	lymphoid	NOUN
aji-178	214	25	organ	organ	NOUN
aji-178	214	26	,	,	PUNCT
aji-178	214	27	including	include	VERB
aji-178	214	28	the	the	DET
aji-178	214	29	spleen	spleen	NOUN
aji-178	214	30	,	,	PUNCT
aji-178	214	31	lymph	lymph	NOUN
aji-178	214	32	nodes	node	NOUN
aji-178	214	33	,	,	PUNCT
aji-178	214	34	or	or	CCONJ
aji-178	214	35	tonsils	tonsil	NOUN
aji-178	214	36	(	(	PUNCT
aji-178	214	37	mangtani	mangtani	X
aji-178	214	38	et	et	PROPN
aji-178	214	39	al	al	PROPN
aji-178	214	40	.	.	PROPN
aji-178	214	41	,	,	PUNCT
aji-178	214	42	2014	2014	NUM
aji-178	214	43	)	)	PUNCT
aji-178	214	44	.	.	PUNCT
aji-178	215	1	the	the	DET
aji-178	215	2	vaccine	vaccine	NOUN
aji-178	215	3	construct	construct	VERB
aji-178	215	4	and	and	CCONJ
aji-178	215	5	the	the	DET
aji-178	215	6	pdb	pdb	NOUN
aji-178	215	7	files	file	NOUN
aji-178	215	8	for	for	ADP
aji-178	215	9	tlr4	tlr4	NOUN
aji-178	215	10	and	and	CCONJ
aji-178	215	11	mhc	mhc	PROPN
aji-178	215	12	i	i	PRON
aji-178	215	13	were	be	AUX
aji-178	215	14	uploaded	upload	VERB
aji-178	215	15	to	to	ADP
aji-178	215	16	cimmsim	cimmsim	NOUN
aji-178	215	17	,	,	PUNCT
aji-178	215	18	using	use	VERB
aji-178	215	19	the	the	DET
aji-178	215	20	default	default	NOUN
aji-178	215	21	settings	setting	NOUN
aji-178	215	22	for	for	ADP
aji-178	215	23	all	all	DET
aji-178	215	24	parameters	parameter	NOUN
aji-178	215	25	.	.	PUNCT
aji-178	216	1	3	3	X
aji-178	216	2	.	.	NOUN
aji-178	216	3	results	result	VERB
aji-178	216	4	1	1	NUM
aji-178	216	5	.	.	X
aji-178	216	6	b	b	X
aji-178	216	7	-	-	PUNCT
aji-178	216	8	cell	cell	NOUN
aji-178	216	9	epitopes	epitope	NOUN
aji-178	216	10	prediction	prediction	NOUN
aji-178	216	11	:	:	PUNCT
aji-178	216	12	a	a	DET
aji-178	216	13	total	total	NOUN
aji-178	216	14	of	of	ADP
aji-178	216	15	thirty	thirty	NUM
aji-178	216	16	b	b	NOUN
aji-178	216	17	-	-	PUNCT
aji-178	216	18	cell	cell	NOUN
aji-178	216	19	epitopes	epitope	NOUN
aji-178	216	20	were	be	AUX
aji-178	216	21	first	first	ADV
aji-178	216	22	predicted	predict	VERB
aji-178	216	23	with	with	ADP
aji-178	216	24	abcpred	abcpre	VERB
aji-178	216	25	and	and	CCONJ
aji-178	216	26	then	then	ADV
aji-178	216	27	evaluated	evaluate	VERB
aji-178	216	28	for	for	ADP
aji-178	216	29	their	their	PRON
aji-178	216	30	antigenic	antigenic	ADJ
aji-178	216	31	,	,	PUNCT
aji-178	216	32	toxic	toxic	ADJ
aji-178	216	33	,	,	PUNCT
aji-178	216	34	and	and	CCONJ
aji-178	216	35	allergenic	allergenic	ADJ
aji-178	216	36	properties	property	NOUN
aji-178	216	37	.	.	PUNCT
aji-178	217	1	epitopes	epitope	NOUN
aji-178	217	2	identified	identify	VERB
aji-178	217	3	as	as	ADP
aji-178	217	4	toxic	toxic	ADJ
aji-178	217	5	,	,	PUNCT
aji-178	217	6	allergenic	allergenic	NOUN
aji-178	217	7	,	,	PUNCT
aji-178	217	8	or	or	CCONJ
aji-178	217	9	nonantigenic	nonantigenic	ADJ
aji-178	217	10	through	through	ADP
aji-178	217	11	toxinpred	toxinpre	VERB
aji-178	217	12	,	,	PUNCT
aji-178	217	13	allertop	allertop	VERB
aji-178	217	14	v.2.0	v.2.0	ADJ
aji-178	217	15	,	,	PUNCT
aji-178	217	16	and	and	CCONJ
aji-178	217	17	vaxijen	vaxijen	NOUN
aji-178	217	18	,	,	PUNCT
aji-178	217	19	respectively	respectively	ADV
aji-178	217	20	,	,	PUNCT
aji-178	217	21	were	be	AUX
aji-178	217	22	excluded	exclude	VERB
aji-178	217	23	from	from	ADP
aji-178	217	24	further	further	ADJ
aji-178	217	25	analysis	analysis	NOUN
aji-178	217	26	.	.	PUNCT
aji-178	218	1	ultimately	ultimately	ADV
aji-178	218	2	,	,	PUNCT
aji-178	218	3	fourteen	fourteen	NUM
aji-178	218	4	b	b	X
aji-178	218	5	-	-	PUNCT
aji-178	218	6	cell	cell	NOUN
aji-178	218	7	epitopes	epitope	NOUN
aji-178	218	8	were	be	AUX
aji-178	218	9	selected	select	VERB
aji-178	218	10	for	for	ADP
aji-178	218	11	inclusion	inclusion	NOUN
aji-178	218	12	in	in	ADP
aji-178	218	13	the	the	DET
aji-178	218	14	vaccine	vaccine	NOUN
aji-178	218	15	construct	construct	VERB
aji-178	218	16	.	.	PUNCT
aji-178	219	1	2	2	X
aji-178	219	2	.	.	X
aji-178	219	3	htl	htl	PROPN
aji-178	219	4	epitopes	epitope	NOUN
aji-178	219	5	prediction	prediction	NOUN
aji-178	219	6	:	:	PUNCT
aji-178	219	7	from	from	ADP
aji-178	219	8	the	the	DET
aji-178	219	9	initial	initial	ADJ
aji-178	219	10	set	set	NOUN
aji-178	219	11	of	of	ADP
aji-178	219	12	twenty	twenty	NUM
aji-178	219	13	predicted	predict	VERB
aji-178	219	14	htl	htl	PROPN
aji-178	219	15	epitopes	epitope	NOUN
aji-178	219	16	,	,	PUNCT
aji-178	219	17	only	only	ADV
aji-178	219	18	those	those	PRON
aji-178	219	19	exhibiting	exhibit	VERB
aji-178	219	20	antigenic	antigenic	ADJ
aji-178	219	21	,	,	PUNCT
aji-178	219	22	nontoxic	nontoxic	ADJ
aji-178	219	23	,	,	PUNCT
aji-178	219	24	and	and	CCONJ
aji-178	219	25	non	non	ADJ
aji-178	219	26	-	-	ADJ
aji-178	219	27	allergenic	allergenic	ADJ
aji-178	219	28	properties	property	NOUN
aji-178	219	29	were	be	AUX
aji-178	219	30	considered	consider	VERB
aji-178	219	31	.	.	PUNCT
aji-178	220	1	using	use	VERB
aji-178	220	2	these	these	DET
aji-178	220	3	criteria	criterion	NOUN
aji-178	220	4	,	,	PUNCT
aji-178	220	5	five	five	NUM
aji-178	220	6	htl	htl	PROPN
aji-178	220	7	epitopes	epitope	NOUN
aji-178	220	8	were	be	AUX
aji-178	220	9	selected	select	VERB
aji-178	220	10	for	for	ADP
aji-178	220	11	inclusion	inclusion	NOUN
aji-178	220	12	in	in	ADP
aji-178	220	13	the	the	DET
aji-178	220	14	vaccine	vaccine	NOUN
aji-178	220	15	construct	construct	VERB
aji-178	220	16	.	.	PUNCT
aji-178	221	1	3	3	X
aji-178	221	2	.	.	X
aji-178	221	3	ctl	ctl	PROPN
aji-178	221	4	epitopes	epitopes	PROPN
aji-178	221	5	prediction	prediction	NOUN
aji-178	221	6	:	:	PUNCT
aji-178	221	7	twenty	twenty	NUM
aji-178	221	8	ctl	ctl	PROPN
aji-178	221	9	epitopes	epitope	VERB
aji-178	221	10	with	with	ADP
aji-178	221	11	the	the	DET
aji-178	221	12	highest	high	ADJ
aji-178	221	13	binding	bind	VERB
aji-178	221	14	affinity	affinity	NOUN
aji-178	221	15	to	to	ADP
aji-178	221	16	mhc	mhc	PROPN
aji-178	221	17	class	class	NOUN
aji-178	221	18	i	i	PRON
aji-178	221	19	molecules	molecule	NOUN
aji-178	221	20	were	be	AUX
aji-178	221	21	selected	select	VERB
aji-178	221	22	for	for	ADP
aji-178	221	23	further	further	ADJ
aji-178	221	24	evaluation	evaluation	NOUN
aji-178	221	25	of	of	ADP
aji-178	221	26	allergenicity	allergenicity	NOUN
aji-178	221	27	,	,	PUNCT
aji-178	221	28	antigenicity	antigenicity	NOUN
aji-178	221	29	,	,	PUNCT
aji-178	221	30	and	and	CCONJ
aji-178	221	31	toxicity	toxicity	NOUN
aji-178	221	32	.	.	PUNCT
aji-178	222	1	any	any	DET
aji-178	222	2	duplicate	duplicate	ADJ
aji-178	222	3	epitopes	epitope	NOUN
aji-178	222	4	found	find	VERB
aji-178	222	5	across	across	ADP
aji-178	222	6	multiple	multiple	ADJ
aji-178	222	7	hla	hla	NOUN
aji-178	222	8	sets	set	NOUN
aji-178	222	9	were	be	AUX
aji-178	222	10	removed	remove	VERB
aji-178	222	11	.	.	PUNCT
aji-178	223	1	only	only	ADV
aji-178	223	2	epitopes	epitope	NOUN
aji-178	223	3	that	that	PRON
aji-178	223	4	were	be	AUX
aji-178	223	5	non	non	ADJ
aji-178	223	6	-	-	ADJ
aji-178	223	7	allergenic	allergenic	ADJ
aji-178	223	8	,	,	PUNCT
aji-178	223	9	non	non	ADJ
aji-178	223	10	-	-	ADJ
aji-178	223	11	toxic	toxic	ADJ
aji-178	223	12	,	,	PUNCT
aji-178	223	13	and	and	CCONJ
aji-178	223	14	antigenic	antigenic	ADJ
aji-178	223	15	were	be	AUX
aji-178	223	16	retained	retain	VERB
aji-178	223	17	for	for	ADP
aji-178	223	18	downstream	downstream	ADJ
aji-178	223	19	analyses	analysis	NOUN
aji-178	223	20	.	.	PUNCT
aji-178	224	1	in	in	ADP
aji-178	224	2	total	total	ADJ
aji-178	224	3	,	,	PUNCT
aji-178	224	4	five	five	NUM
aji-178	224	5	ctl	ctl	PROPN
aji-178	224	6	epitopes	epitope	NOUN
aji-178	224	7	and	and	CCONJ
aji-178	224	8	three	three	NUM
aji-178	224	9	hla	hla	PROPN
aji-178	224	10	-	-	PUNCT
aji-178	224	11	c	c	NOUN
aji-178	224	12	epitopes	epitope	NOUN
aji-178	224	13	derived	derive	VERB
aji-178	224	14	from	from	ADP
aji-178	224	15	ppe39	ppe39	PROPN
aji-178	224	16	,	,	PUNCT
aji-178	224	17	ppe68	ppe68	NOUN
aji-178	224	18	,	,	PUNCT
aji-178	224	19	rv0310c	rv0310c	PROPN
aji-178	224	20	,	,	PUNCT
aji-178	224	21	pe_pgrs35	pe_pgrs35	PROPN
aji-178	224	22	,	,	PUNCT
aji-178	224	23	pe_pgrs31	pe_pgrs31	NOUN
aji-178	224	24	,	,	PUNCT
aji-178	224	25	cfp10	cfp10	NOUN
aji-178	224	26	,	,	PUNCT
aji-178	224	27	rv1975	rv1975	PROPN
aji-178	224	28	,	,	PUNCT
aji-178	224	29	lpqg	lpqg	NOUN
aji-178	224	30	,	,	PUNCT
aji-178	224	31	esxv	esxv	NOUN
aji-178	224	32	,	,	PUNCT
aji-178	224	33	and	and	CCONJ
aji-178	224	34	espj	espj	NOUN
aji-178	224	35	were	be	AUX
aji-178	224	36	selected	select	VERB
aji-178	224	37	for	for	ADP
aji-178	224	38	vaccine	vaccine	NOUN
aji-178	224	39	construction	construction	NOUN
aji-178	224	40	.	.	PUNCT
aji-178	225	1	4	4	X
aji-178	225	2	.	.	X
aji-178	225	3	vaccine	vaccine	NOUN
aji-178	225	4	construct	construct	VERB
aji-178	225	5	preparation	preparation	NOUN
aji-178	225	6	:	:	PUNCT
aji-178	225	7	two	two	NUM
aji-178	225	8	random	random	ADJ
aji-178	225	9	vaccine	vaccine	NOUN
aji-178	225	10	constructs	construct	NOUN
aji-178	225	11	were	be	AUX
aji-178	225	12	generated	generate	VERB
aji-178	225	13	by	by	ADP
aji-178	225	14	shuffling	shuffle	VERB
aji-178	225	15	the	the	DET
aji-178	225	16	arrangement	arrangement	NOUN
aji-178	225	17	of	of	ADP
aji-178	225	18	the	the	DET
aji-178	225	19	selected	select	VERB
aji-178	225	20	epitopes	epitope	NOUN
aji-178	225	21	.	.	PUNCT
aji-178	226	1	in	in	ADP
aji-178	226	2	each	each	DET
aji-178	226	3	construct	construct	NOUN
aji-178	226	4	,	,	PUNCT
aji-178	226	5	the	the	DET
aji-178	226	6	epitopes	epitope	NOUN
aji-178	226	7	were	be	AUX
aji-178	226	8	organized	organize	VERB
aji-178	226	9	in	in	ADP
aji-178	226	10	the	the	DET
aji-178	226	11	order	order	NOUN
aji-178	226	12	of	of	ADP
aji-178	226	13	b	b	NOUN
aji-178	226	14	-	-	PUNCT
aji-178	226	15	cell	cell	NOUN
aji-178	226	16	,	,	PUNCT
aji-178	226	17	htl	htl	PROPN
aji-178	226	18	,	,	PUNCT
aji-178	226	19	ctl	ctl	PROPN
aji-178	226	20	,	,	PUNCT
aji-178	226	21	and	and	CCONJ
aji-178	226	22	hla	hla	PROPN
aji-178	226	23	-	-	PUNCT
aji-178	226	24	c.	c.	NOUN
aji-178	226	25	the	the	DET
aji-178	226	26	b	b	NOUN
aji-178	226	27	-	-	PUNCT
aji-178	226	28	cell	cell	NOUN
aji-178	226	29	,	,	PUNCT
aji-178	226	30	htl	htl	PROPN
aji-178	226	31	,	,	PUNCT
aji-178	226	32	ctl	ctl	PROPN
aji-178	226	33	,	,	PUNCT
aji-178	226	34	and	and	CCONJ
aji-178	226	35	hla	hla	PROPN
aji-178	226	36	-	-	PUNCT
aji-178	226	37	c	c	NOUN
aji-178	226	38	epitopes	epitope	NOUN
aji-178	226	39	were	be	AUX
aji-178	226	40	connected	connect	VERB
aji-178	226	41	using	use	VERB
aji-178	226	42	kk	kk	PROPN
aji-178	226	43	,	,	PUNCT
aji-178	226	44	gpgpg	gpgpg	NOUN
aji-178	226	45	,	,	PUNCT
aji-178	226	46	and	and	CCONJ
aji-178	226	47	aay	aay	PROPN
aji-178	226	48	linkers	linker	NOUN
aji-178	226	49	,	,	PUNCT
aji-178	226	50	respectively	respectively	ADV
aji-178	226	51	.	.	PUNCT
aji-178	227	1	the	the	DET
aji-178	227	2	adjuvant	adjuvant	ADJ
aji-178	227	3	proteins	protein	NOUN
aji-178	227	4	rpfe	rpfe	VERB
aji-178	227	5	and	and	CCONJ
aji-178	227	6	rpfb	rpfb	NOUN
aji-178	227	7	were	be	AUX
aji-178	227	8	attached	attach	VERB
aji-178	227	9	to	to	ADP
aji-178	227	10	the	the	DET
aji-178	227	11	n	n	CCONJ
aji-178	227	12	-	-	PUNCT
aji-178	227	13	terminal	terminal	ADJ
aji-178	227	14	end	end	NOUN
aji-178	227	15	of	of	ADP
aji-178	227	16	the	the	DET
aji-178	227	17	vaccine	vaccine	NOUN
aji-178	227	18	constructs	construct	VERB
aji-178	227	19	via	via	ADP
aji-178	227	20	an	an	DET
aji-178	227	21	eaaak	eaaak	NOUN
aji-178	227	22	linker	linker	NOUN
aji-178	227	23	.	.	PUNCT
aji-178	228	1	5	5	NUM
aji-178	228	2	.	.	X
aji-178	228	3	homology	homology	NOUN
aji-178	228	4	modelling	modelling	NOUN
aji-178	228	5	and	and	CCONJ
aji-178	228	6	selection	selection	NOUN
aji-178	228	7	of	of	ADP
aji-178	228	8	best	good	ADJ
aji-178	228	9	vaccine	vaccine	NOUN
aji-178	228	10	construct	construct	VERB
aji-178	228	11	:	:	PUNCT
aji-178	228	12	homology	homology	NOUN
aji-178	228	13	modelling	modelling	NOUN
aji-178	228	14	and	and	CCONJ
aji-178	228	15	structural	structural	ADJ
aji-178	228	16	validation	validation	NOUN
aji-178	228	17	of	of	ADP
aji-178	228	18	the	the	DET
aji-178	228	19	vaccine	vaccine	NOUN
aji-178	228	20	constructs	construct	NOUN
aji-178	228	21	were	be	AUX
aji-178	228	22	performed	perform	VERB
aji-178	228	23	using	use	VERB
aji-178	228	24	the	the	DET
aji-178	228	25	swiss	swiss	ADJ
aji-178	228	26	-	-	PUNCT
aji-178	228	27	model	model	NOUN
aji-178	228	28	web	web	NOUN
aji-178	228	29	server	server	NOUN
aji-178	228	30	.	.	PUNCT
aji-178	229	1	the	the	DET
aji-178	229	2	generated	generate	VERB
aji-178	229	3	models	model	NOUN
aji-178	229	4	were	be	AUX
aji-178	229	5	evaluated	evaluate	VERB
aji-178	229	6	based	base	VERB
aji-178	229	7	on	on	ADP
aji-178	229	8	the	the	DET
aji-178	229	9	ramachandran	ramachandran	PROPN
aji-178	229	10	plot	plot	NOUN
aji-178	229	11	statistics	statistic	NOUN
aji-178	229	12	,	,	PUNCT
aji-178	229	13	mean	mean	VERB
aji-178	229	14	score	score	NOUN
aji-178	229	15	,	,	PUNCT
aji-178	229	16	and	and	CCONJ
aji-178	229	17	naseema	naseema	NOUN
aji-178	229	18	;	;	PUNCT
aji-178	229	19	asian	asian	ADJ
aji-178	229	20	j.	j.	PROPN
aji-178	229	21	immunol	immunol	PROPN
aji-178	229	22	.	.	PROPN
aji-178	230	1	,	,	PUNCT
aji-178	230	2	vol	vol	NOUN
aji-178	230	3	.	.	PROPN
aji-178	230	4	8	8	NUM
aji-178	230	5	,	,	PUNCT
aji-178	230	6	no	no	INTJ
aji-178	230	7	.	.	NOUN
aji-178	230	8	1	1	NUM
aji-178	230	9	,	,	PUNCT
aji-178	230	10	pp	pp	ADJ
aji-178	230	11	.	.	PUNCT
aji-178	231	1	269	269	NUM
aji-178	231	2	-	-	SYM
aji-178	231	3	284	284	NUM
aji-178	231	4	,	,	PUNCT
aji-178	231	5	2025	2025	NUM
aji-178	231	6	;	;	PUNCT
aji-178	231	7	article	article	NOUN
aji-178	231	8	no.aji.147582	no.aji.147582	NOUN
aji-178	231	9	274	274	NUM
aji-178	231	10	z	z	NOUN
aji-178	231	11	-	-	PUNCT
aji-178	231	12	score	score	NOUN
aji-178	231	13	provided	provide	VERB
aji-178	231	14	by	by	ADP
aji-178	231	15	swiss	swiss	ADJ
aji-178	231	16	-	-	PUNCT
aji-178	231	17	model	model	NOUN
aji-178	231	18	reports	report	NOUN
aji-178	231	19	.	.	PUNCT
aji-178	232	1	among	among	ADP
aji-178	232	2	all	all	DET
aji-178	232	3	constructs	construct	NOUN
aji-178	232	4	,	,	PUNCT
aji-178	232	5	vaccine	vaccine	NOUN
aji-178	232	6	construct	construct	VERB
aji-178	232	7	1	1	NUM
aji-178	232	8	exhibited	exhibit	VERB
aji-178	232	9	the	the	DET
aji-178	232	10	most	most	ADV
aji-178	232	11	favorable	favorable	ADJ
aji-178	232	12	results	result	NOUN
aji-178	232	13	,	,	PUNCT
aji-178	232	14	with	with	ADP
aji-178	232	15	residues	residue	NOUN
aji-178	232	16	in	in	ADP
aji-178	232	17	the	the	DET
aji-178	232	18	most	most	ADV
aji-178	232	19	preferred	preferred	ADJ
aji-178	232	20	regions	region	NOUN
aji-178	232	21	,	,	PUNCT
aji-178	232	22	additionally	additionally	ADV
aji-178	232	23	allowed	allow	VERB
aji-178	232	24	regions	region	NOUN
aji-178	232	25	,	,	PUNCT
aji-178	232	26	generously	generously	ADV
aji-178	232	27	allowed	allow	VERB
aji-178	232	28	regions	region	NOUN
aji-178	232	29	,	,	PUNCT
aji-178	232	30	and	and	CCONJ
aji-178	232	31	disallowed	disallow	VERB
aji-178	232	32	regions	region	NOUN
aji-178	232	33	accounting	account	VERB
aji-178	232	34	for	for	ADP
aji-178	232	35	93.06	93.06	NUM
aji-178	232	36	%	%	NOUN
aji-178	232	37	,	,	PUNCT
aji-178	232	38	5.17	5.17	NUM
aji-178	232	39	%	%	NOUN
aji-178	232	40	,	,	PUNCT
aji-178	232	41	1.77	1.77	NUM
aji-178	232	42	%	%	NOUN
aji-178	232	43	,	,	PUNCT
aji-178	232	44	and	and	CCONJ
aji-178	232	45	0.0	0.0	NUM
aji-178	232	46	%	%	NOUN
aji-178	232	47	,	,	PUNCT
aji-178	232	48	respectively	respectively	ADV
aji-178	232	49	.	.	PUNCT
aji-178	233	1	while	while	SCONJ
aji-178	233	2	the	the	DET
aji-178	233	3	z	z	NOUN
aji-178	233	4	-	-	PUNCT
aji-178	233	5	score	score	NOUN
aji-178	233	6	,	,	PUNCT
aji-178	233	7	rmsd	rmsd	NOUN
aji-178	233	8	,	,	PUNCT
aji-178	233	9	molprobity	molprobity	NOUN
aji-178	233	10	,	,	PUNCT
aji-178	233	11	clash	clash	VERB
aji-178	233	12	score	score	NOUN
aji-178	233	13	for	for	ADP
aji-178	233	14	verify3d	verify3d	NOUN
aji-178	233	15	were	be	AUX
aji-178	233	16	-1.10,0.248,1.39	-1.10,0.248,1.39	PUNCT
aji-178	233	17	and	and	CCONJ
aji-178	233	18	6.9	6.9	NUM
aji-178	233	19	respectively	respectively	ADV
aji-178	233	20	.	.	PUNCT
aji-178	234	1	the	the	DET
aji-178	234	2	final	final	ADJ
aji-178	234	3	chosen	choose	VERB
aji-178	234	4	vaccine	vaccine	NOUN
aji-178	234	5	construct	construct	NOUN
aji-178	234	6	was	be	AUX
aji-178	234	7	also	also	ADV
aji-178	234	8	analyzed	analyze	VERB
aji-178	234	9	for	for	SCONJ
aji-178	234	10	its	its	PRON
aji-178	234	11	antigenicity	antigenicity	NOUN
aji-178	234	12	using	use	VERB
aji-178	234	13	vaxijen	vaxijen	NOUN
aji-178	234	14	tool	tool	NOUN
aji-178	234	15	where	where	SCONJ
aji-178	234	16	antigenicity	antigenicity	NOUN
aji-178	234	17	was	be	AUX
aji-178	234	18	predicted	predict	VERB
aji-178	234	19	to	to	PART
aji-178	234	20	be	be	AUX
aji-178	234	21	1.0664	1.0664	NUM
aji-178	234	22	.	.	PUNCT
aji-178	235	1	the	the	DET
aji-178	235	2	chosen	choose	VERB
aji-178	235	3	vaccine	vaccine	NOUN
aji-178	235	4	construct	construct	VERB
aji-178	235	5	sequence	sequence	NOUN
aji-178	235	6	is	be	AUX
aji-178	235	7	shown	show	VERB
aji-178	235	8	in	in	ADP
aji-178	235	9	supplementary	supplementary	ADJ
aji-178	235	10	fig.1	fig.1	PROPN
aji-178	235	11	and	and	CCONJ
aji-178	235	12	the	the	DET
aji-178	235	13	graphical	graphical	ADJ
aji-178	235	14	representation	representation	NOUN
aji-178	235	15	of	of	ADP
aji-178	235	16	vaccine	vaccine	NOUN
aji-178	235	17	construct	construct	VERB
aji-178	235	18	in	in	ADP
aji-178	235	19	order	order	NOUN
aji-178	235	20	of	of	ADP
aji-178	235	21	epitopes	epitope	NOUN
aji-178	235	22	utilized	utilize	VERB
aji-178	235	23	can	can	AUX
aji-178	235	24	be	be	AUX
aji-178	235	25	found	find	VERB
aji-178	235	26	in	in	ADP
aji-178	235	27	fig	fig	NOUN
aji-178	235	28	.	.	PUNCT
aji-178	236	1	1	1	NUM
aji-178	236	2	.	.	NUM
aji-178	236	3	6	6	NUM
aji-178	236	4	.	.	X
aji-178	236	5	vaccine	vaccine	NOUN
aji-178	236	6	construct	construct	VERB
aji-178	236	7	tertiary	tertiary	ADJ
aji-178	236	8	structure	structure	NOUN
aji-178	236	9	refinement	refinement	NOUN
aji-178	236	10	:	:	PUNCT
aji-178	236	11	the	the	DET
aji-178	236	12	homology	homology	NOUN
aji-178	236	13	model	model	NOUN
aji-178	236	14	generated	generate	VERB
aji-178	236	15	using	use	VERB
aji-178	236	16	swiss	swiss	ADJ
aji-178	236	17	model	model	NOUN
aji-178	236	18	(	(	PUNCT
aji-178	236	19	fig	fig	NOUN
aji-178	236	20	.	.	PUNCT
aji-178	237	1	2a	2a	NUM
aji-178	237	2	)	)	PUNCT
aji-178	238	1	is	be	AUX
aji-178	238	2	exhibiting	exhibit	VERB
aji-178	238	3	the	the	DET
aji-178	238	4	finest	fine	ADJ
aji-178	238	5	ramachandran	ramachandran	NOUN
aji-178	238	6	plot	plot	NOUN
aji-178	238	7	values	value	NOUN
aji-178	238	8	was	be	AUX
aji-178	238	9	exposed	expose	VERB
aji-178	238	10	to	to	ADP
aji-178	238	11	improvement	improvement	NOUN
aji-178	238	12	using	use	VERB
aji-178	238	13	castp	castp	NOUN
aji-178	238	14	.	.	PUNCT
aji-178	239	1	out	out	ADP
aji-178	239	2	of	of	ADP
aji-178	239	3	all	all	DET
aji-178	239	4	the	the	DET
aji-178	239	5	five	five	NUM
aji-178	239	6	models	model	NOUN
aji-178	239	7	generated	generate	VERB
aji-178	239	8	by	by	ADP
aji-178	239	9	castp	castp	PROPN
aji-178	239	10	,	,	PUNCT
aji-178	239	11	model	model	NOUN
aji-178	239	12	2	2	NUM
aji-178	239	13	(	(	PUNCT
aji-178	239	14	fig	fig	NOUN
aji-178	239	15	.	.	PUNCT
aji-178	239	16	2b	2b	NOUN
aji-178	239	17	)	)	PUNCT
aji-178	239	18	was	be	AUX
aji-178	239	19	found	find	VERB
aji-178	239	20	to	to	PART
aji-178	239	21	be	be	AUX
aji-178	239	22	most	most	ADV
aji-178	239	23	appropriate	appropriate	ADJ
aji-178	239	24	where	where	SCONJ
aji-178	239	25	values	value	NOUN
aji-178	239	26	for	for	ADP
aji-178	239	27	gdt	gdt	NOUN
aji-178	239	28	-	-	PUNCT
aji-178	239	29	ha	ha	ADJ
aji-178	239	30	,	,	PUNCT
aji-178	239	31	rmsd	rmsd	NOUN
aji-178	239	32	and	and	CCONJ
aji-178	239	33	molprobity	molprobity	NOUN
aji-178	239	34	were	be	AUX
aji-178	239	35	0.993	0.993	NUM
aji-178	239	36	,	,	PUNCT
aji-178	239	37	0.248	0.248	NUM
aji-178	239	38	and	and	CCONJ
aji-178	239	39	1.378	1.378	NUM
aji-178	239	40	respectively	respectively	ADV
aji-178	239	41	.	.	PUNCT
aji-178	240	1	after	after	ADP
aji-178	240	2	refinement	refinement	NOUN
aji-178	240	3	,	,	PUNCT
aji-178	240	4	the	the	DET
aji-178	240	5	most	most	ADV
aji-178	240	6	preferred	preferred	ADJ
aji-178	240	7	regions	region	NOUN
aji-178	240	8	of	of	ADP
aji-178	240	9	ramachandran	ramachandran	PROPN
aji-178	240	10	increased	increase	VERB
aji-178	240	11	to	to	ADP
aji-178	240	12	93.72	93.72	NUM
aji-178	240	13	%	%	NOUN
aji-178	240	14	when	when	SCONJ
aji-178	240	15	compared	compare	VERB
aji-178	240	16	to	to	ADP
aji-178	240	17	the	the	DET
aji-178	240	18	structure	structure	NOUN
aji-178	240	19	obtained	obtain	VERB
aji-178	240	20	from	from	ADP
aji-178	240	21	swiss	swiss	ADJ
aji-178	240	22	model	model	NOUN
aji-178	240	23	(	(	PUNCT
aji-178	240	24	fig.3	fig.3	PROPN
aji-178	240	25	)	)	PUNCT
aji-178	240	26	.	.	PUNCT
aji-178	241	1	at	at	ADP
aji-178	241	2	last	last	ADV
aji-178	241	3	,	,	PUNCT
aji-178	241	4	the	the	DET
aji-178	241	5	refined	refined	ADJ
aji-178	241	6	model	model	NOUN
aji-178	241	7	2	2	NUM
aji-178	241	8	was	be	AUX
aji-178	241	9	chosen	choose	VERB
aji-178	241	10	for	for	ADP
aji-178	241	11	further	further	ADJ
aji-178	241	12	investigations	investigation	NOUN
aji-178	241	13	like	like	ADP
aji-178	241	14	molecular	molecular	ADJ
aji-178	241	15	docking	docking	NOUN
aji-178	241	16	and	and	CCONJ
aji-178	241	17	dynamic	dynamic	ADJ
aji-178	241	18	simulations	simulation	NOUN
aji-178	241	19	.	.	PUNCT
aji-178	242	1	fig	fig	NOUN
aji-178	242	2	.	.	PUNCT
aji-178	243	1	3	3	X
aji-178	243	2	.	.	X
aji-178	243	3	ramachandran	ramachandran	PROPN
aji-178	243	4	plot	plot	NOUN
aji-178	243	5	analysis	analysis	NOUN
aji-178	243	6	of	of	ADP
aji-178	243	7	the	the	DET
aji-178	243	8	refined	refined	ADJ
aji-178	243	9	tertiary	tertiary	ADJ
aji-178	243	10	structure	structure	NOUN
aji-178	243	11	of	of	ADP
aji-178	243	12	vaccine	vaccine	NOUN
aji-178	243	13	construct	construct	NOUN
aji-178	243	14	obtained	obtain	VERB
aji-178	243	15	from	from	ADP
aji-178	243	16	rampage	rampage	NOUN
aji-178	243	17	web	web	NOUN
aji-178	243	18	server	server	NOUN
aji-178	243	19	.	.	PUNCT
aji-178	244	1	after	after	ADP
aji-178	244	2	refinement	refinement	NOUN
aji-178	244	3	,	,	PUNCT
aji-178	244	4	most	most	ADV
aji-178	244	5	preferred	preferred	ADJ
aji-178	244	6	regions	region	NOUN
aji-178	244	7	increased	increase	VERB
aji-178	244	8	to	to	ADP
aji-178	244	9	93.72	93.72	NUM
aji-178	244	10	%	%	NOUN
aji-178	244	11	as	as	ADP
aji-178	244	12	compared	compare	VERB
aji-178	244	13	to	to	ADP
aji-178	244	14	the	the	DET
aji-178	244	15	crude	crude	ADJ
aji-178	244	16	3d	3d	NOUN
aji-178	244	17	structure	structure	NOUN
aji-178	244	18	derived	derive	VERB
aji-178	244	19	from	from	ADP
aji-178	244	20	swiss	swiss	ADJ
aji-178	244	21	model	model	NOUN
aji-178	244	22	where	where	SCONJ
aji-178	244	23	the	the	DET
aji-178	244	24	most	most	ADV
aji-178	244	25	favoured	favour	VERB
aji-178	244	26	regions	region	NOUN
aji-178	244	27	were	be	AUX
aji-178	244	28	93.06	93.06	NUM
aji-178	244	29	%	%	NOUN
aji-178	244	30	naseema	naseema	NOUN
aji-178	244	31	;	;	PUNCT
aji-178	244	32	asian	asian	ADJ
aji-178	244	33	j.	j.	PROPN
aji-178	244	34	immunol	immunol	PROPN
aji-178	244	35	.	.	PROPN
aji-178	244	36	,	,	PUNCT
aji-178	244	37	vol	vol	NOUN
aji-178	244	38	.	.	PROPN
aji-178	244	39	8	8	NUM
aji-178	244	40	,	,	PUNCT
aji-178	244	41	no	no	INTJ
aji-178	244	42	.	.	NOUN
aji-178	244	43	1	1	NUM
aji-178	244	44	,	,	PUNCT
aji-178	244	45	pp	pp	ADJ
aji-178	244	46	.	.	PUNCT
aji-178	245	1	269	269	NUM
aji-178	245	2	-	-	SYM
aji-178	245	3	284	284	NUM
aji-178	245	4	,	,	PUNCT
aji-178	245	5	2025	2025	NUM
aji-178	245	6	;	;	PUNCT
aji-178	245	7	article	article	NOUN
aji-178	245	8	no.aji.147582	no.aji.147582	VERB
aji-178	245	9	275	275	NUM
aji-178	245	10	7	7	NUM
aji-178	245	11	.	.	PUNCT
aji-178	246	1	vaccine	vaccine	NOUN
aji-178	246	2	constructs	construct	VERB
aji-178	246	3	physicochemical	physicochemical	ADJ
aji-178	246	4	properties	property	NOUN
aji-178	246	5	:	:	PUNCT
aji-178	246	6	the	the	DET
aji-178	246	7	selected	select	VERB
aji-178	246	8	refined	refined	ADJ
aji-178	246	9	vaccine	vaccine	NOUN
aji-178	246	10	construct	construct	VERB
aji-178	246	11	consisted	consist	VERB
aji-178	246	12	of	of	ADP
aji-178	246	13	623	623	NUM
aji-178	246	14	amino	amino	ADJ
aji-178	246	15	acids	acid	NOUN
aji-178	246	16	with	with	ADP
aji-178	246	17	an	an	DET
aji-178	246	18	estimated	estimate	VERB
aji-178	246	19	molecular	molecular	ADJ
aji-178	246	20	weight	weight	NOUN
aji-178	246	21	of	of	ADP
aji-178	246	22	61.83	61.83	NUM
aji-178	246	23	kda	kda	NOUN
aji-178	246	24	.	.	PUNCT
aji-178	247	1	typically	typically	ADV
aji-178	247	2	,	,	PUNCT
aji-178	247	3	vaccine	vaccine	NOUN
aji-178	247	4	candidates	candidate	NOUN
aji-178	247	5	with	with	ADP
aji-178	247	6	molecular	molecular	ADJ
aji-178	247	7	masses	masse	NOUN
aji-178	247	8	greater	great	ADJ
aji-178	247	9	than	than	ADP
aji-178	247	10	50	50	NUM
aji-178	247	11	kda	kda	NOUN
aji-178	247	12	are	be	AUX
aji-178	247	13	preferred	prefer	VERB
aji-178	247	14	,	,	PUNCT
aji-178	247	15	as	as	SCONJ
aji-178	247	16	those	those	PRON
aji-178	247	17	with	with	ADP
aji-178	247	18	lower	low	ADJ
aji-178	247	19	molecular	molecular	ADJ
aji-178	247	20	weights	weight	NOUN
aji-178	247	21	tend	tend	VERB
aji-178	247	22	to	to	PART
aji-178	247	23	exhibit	exhibit	VERB
aji-178	247	24	reduced	reduce	VERB
aji-178	247	25	lymph	lymph	NOUN
aji-178	247	26	node	node	ADJ
aji-178	247	27	accumulation	accumulation	NOUN
aji-178	247	28	.	.	PUNCT
aji-178	248	1	the	the	DET
aji-178	248	2	construct	construct	NOUN
aji-178	248	3	has	have	VERB
aji-178	248	4	a	a	DET
aji-178	248	5	theoretical	theoretical	ADJ
aji-178	248	6	pi	pi	NOUN
aji-178	248	7	of	of	ADP
aji-178	248	8	9.10	9.10	NUM
aji-178	248	9	,	,	PUNCT
aji-178	248	10	containing	contain	VERB
aji-178	248	11	39	39	NUM
aji-178	248	12	negatively	negatively	ADV
aji-178	248	13	and	and	CCONJ
aji-178	248	14	49	49	NUM
aji-178	248	15	positively	positively	ADV
aji-178	248	16	charged	charge	VERB
aji-178	248	17	residues	residue	NOUN
aji-178	248	18	,	,	PUNCT
aji-178	248	19	suggesting	suggest	VERB
aji-178	248	20	a	a	DET
aji-178	248	21	basic	basic	ADJ
aji-178	248	22	nature	nature	NOUN
aji-178	248	23	.	.	PUNCT
aji-178	249	1	its	its	PRON
aji-178	249	2	predicted	predict	VERB
aji-178	249	3	half	half	ADJ
aji-178	249	4	-	-	PUNCT
aji-178	249	5	life	life	NOUN
aji-178	249	6	is	be	AUX
aji-178	249	7	around	around	ADV
aji-178	249	8	30	30	NUM
aji-178	249	9	hours	hour	NOUN
aji-178	249	10	in	in	ADP
aji-178	249	11	mammalian	mammalian	ADJ
aji-178	249	12	reticulocytes	reticulocyte	NOUN
aji-178	249	13	,	,	PUNCT
aji-178	249	14	over	over	ADP
aji-178	249	15	10	10	NUM
aji-178	249	16	hours	hour	NOUN
aji-178	249	17	in	in	ADP
aji-178	249	18	e.	e.	PROPN
aji-178	249	19	coli	coli	PROPN
aji-178	249	20	,	,	PUNCT
aji-178	249	21	and	and	CCONJ
aji-178	249	22	over	over	ADP
aji-178	249	23	20	20	NUM
aji-178	249	24	hours	hour	NOUN
aji-178	249	25	in	in	ADP
aji-178	249	26	yeast	yeast	NOUN
aji-178	249	27	.	.	PUNCT
aji-178	250	1	the	the	DET
aji-178	250	2	aliphatic	aliphatic	ADJ
aji-178	250	3	index	index	NOUN
aji-178	250	4	was	be	AUX
aji-178	250	5	determined	determine	VERB
aji-178	250	6	to	to	PART
aji-178	250	7	be	be	AUX
aji-178	250	8	60.42	60.42	NUM
aji-178	250	9	,	,	PUNCT
aji-178	250	10	and	and	CCONJ
aji-178	250	11	the	the	DET
aji-178	250	12	instability	instability	NOUN
aji-178	250	13	index	index	NOUN
aji-178	250	14	was	be	AUX
aji-178	250	15	31.42	31.42	NUM
aji-178	250	16	,	,	PUNCT
aji-178	250	17	suggesting	suggest	VERB
aji-178	250	18	that	that	SCONJ
aji-178	250	19	the	the	DET
aji-178	250	20	protein	protein	NOUN
aji-178	250	21	is	be	AUX
aji-178	250	22	thermally	thermally	ADV
aji-178	250	23	stable	stable	ADJ
aji-178	250	24	.	.	PUNCT
aji-178	251	1	the	the	DET
aji-178	251	2	grand	grand	ADJ
aji-178	251	3	average	average	NOUN
aji-178	251	4	of	of	ADP
aji-178	251	5	hydropathicity	hydropathicity	NOUN
aji-178	251	6	(	(	PUNCT
aji-178	251	7	gravy	gravy	NOUN
aji-178	251	8	)	)	PUNCT
aji-178	251	9	value	value	NOUN
aji-178	251	10	was	be	AUX
aji-178	251	11	calculated	calculate	VERB
aji-178	251	12	as	as	ADP
aji-178	251	13	−0.282	−0.282	PROPN
aji-178	251	14	,	,	PUNCT
aji-178	251	15	indicating	indicate	VERB
aji-178	251	16	the	the	DET
aji-178	251	17	hydrophilic	hydrophilic	ADJ
aji-178	251	18	nature	nature	NOUN
aji-178	251	19	of	of	ADP
aji-178	251	20	the	the	DET
aji-178	251	21	construct	construct	NOUN
aji-178	251	22	.	.	PUNCT
aji-178	252	1	fig	fig	NOUN
aji-178	252	2	.	.	PUNCT
aji-178	253	1	4	4	X
aji-178	253	2	.	.	X
aji-178	253	3	molecular	molecular	ADJ
aji-178	253	4	docking	docking	NOUN
aji-178	253	5	of	of	ADP
aji-178	253	6	vaccine	vaccine	NOUN
aji-178	253	7	construct	construct	VERB
aji-178	253	8	and	and	CCONJ
aji-178	253	9	tlr4	tlr4	NOUN
aji-178	253	10	ligand	ligand	NOUN
aji-178	253	11	8	8	NUM
aji-178	253	12	.	.	PUNCT
aji-178	254	1	molecular	molecular	ADJ
aji-178	254	2	docking	docking	NOUN
aji-178	254	3	of	of	ADP
aji-178	254	4	vaccine	vaccine	NOUN
aji-178	254	5	construct	construct	VERB
aji-178	254	6	with	with	ADP
aji-178	254	7	tlr4	tlr4	NOUN
aji-178	254	8	:	:	PUNCT
aji-178	254	9	the	the	DET
aji-178	254	10	castp	castp	ADJ
aji-178	254	11	server	server	NOUN
aji-178	254	12	was	be	AUX
aji-178	254	13	employed	employ	VERB
aji-178	254	14	to	to	PART
aji-178	254	15	identify	identify	VERB
aji-178	254	16	the	the	DET
aji-178	254	17	active	active	ADJ
aji-178	254	18	and	and	CCONJ
aji-178	254	19	passive	passive	ADJ
aji-178	254	20	ligand	ligand	NOUN
aji-178	254	21	-	-	PUNCT
aji-178	254	22	binding	bind	VERB
aji-178	254	23	sites	site	NOUN
aji-178	254	24	within	within	ADP
aji-178	254	25	the	the	DET
aji-178	254	26	refined	refined	ADJ
aji-178	254	27	tertiary	tertiary	ADJ
aji-178	254	28	structure	structure	NOUN
aji-178	254	29	of	of	ADP
aji-178	254	30	the	the	DET
aji-178	254	31	vaccine	vaccine	NOUN
aji-178	254	32	construct	construct	VERB
aji-178	254	33	(	(	PUNCT
aji-178	254	34	gülbay	gülbay	NOUN
aji-178	254	35	et	et	PROPN
aji-178	254	36	al	al	PROPN
aji-178	254	37	.	.	PROPN
aji-178	254	38	,	,	PUNCT
aji-178	254	39	2006	2006	NUM
aji-178	254	40	)	)	PUNCT
aji-178	254	41	.	.	PUNCT
aji-178	255	1	the	the	DET
aji-178	255	2	analysis	analysis	NOUN
aji-178	255	3	revealed	reveal	VERB
aji-178	255	4	62	62	NUM
aji-178	255	5	active	active	ADJ
aji-178	255	6	and	and	CCONJ
aji-178	255	7	91	91	NUM
aji-178	255	8	passive	passive	ADJ
aji-178	255	9	ligand	ligand	NOUN
aji-178	255	10	-	-	PUNCT
aji-178	255	11	binding	bind	VERB
aji-178	255	12	residues	residue	NOUN
aji-178	255	13	in	in	ADP
aji-178	255	14	tlr4	tlr4	NOUN
aji-178	255	15	.	.	PUNCT
aji-178	256	1	for	for	SCONJ
aji-178	256	2	the	the	DET
aji-178	256	3	vaccine	vaccine	NOUN
aji-178	256	4	construct	construct	VERB
aji-178	256	5	,	,	PUNCT
aji-178	256	6	129	129	NUM
aji-178	256	7	residues	residue	NOUN
aji-178	256	8	were	be	AUX
aji-178	256	9	identified	identify	VERB
aji-178	256	10	as	as	ADP
aji-178	256	11	active	active	ADJ
aji-178	256	12	and	and	CCONJ
aji-178	256	13	145	145	NUM
aji-178	256	14	as	as	ADP
aji-178	256	15	passive	passive	ADJ
aji-178	256	16	binding	bind	VERB
aji-178	256	17	sites	site	NOUN
aji-178	256	18	.	.	PUNCT
aji-178	257	1	both	both	PRON
aji-178	257	2	the	the	DET
aji-178	257	3	refined	refined	ADJ
aji-178	257	4	construct	construct	NOUN
aji-178	257	5	and	and	CCONJ
aji-178	257	6	tlr4	tlr4	NOUN
aji-178	257	7	monomers	monomer	NOUN
aji-178	257	8	were	be	AUX
aji-178	257	9	subsequently	subsequently	ADV
aji-178	257	10	submitted	submit	VERB
aji-178	257	11	to	to	ADP
aji-178	257	12	the	the	DET
aji-178	257	13	pydock	pydock	NOUN
aji-178	257	14	server	server	NOUN
aji-178	257	15	for	for	ADP
aji-178	257	16	molecular	molecular	ADJ
aji-178	257	17	docking	docking	NOUN
aji-178	257	18	.	.	PUNCT
aji-178	258	1	pydock	pydock	NOUN
aji-178	258	2	provided	provide	VERB
aji-178	258	3	top	top	ADJ
aji-178	258	4	10	10	NUM
aji-178	258	5	models	model	NOUN
aji-178	258	6	in	in	ADP
aji-178	258	7	which	which	DET
aji-178	258	8	model	model	NOUN
aji-178	258	9	1	1	NUM
aji-178	258	10	was	be	AUX
aji-178	258	11	selected	select	VERB
aji-178	258	12	.	.	PUNCT
aji-178	259	1	other	other	ADJ
aji-178	259	2	calculated	calculate	VERB
aji-178	259	3	parameters	parameter	NOUN
aji-178	259	4	are	be	AUX
aji-178	259	5	provided	provide	VERB
aji-178	259	6	in	in	ADP
aji-178	259	7	supplementary	supplementary	ADJ
aji-178	259	8	table	table	NOUN
aji-178	259	9	2	2	NUM
aji-178	259	10	.	.	PUNCT
aji-178	260	1	the	the	DET
aji-178	260	2	docked	docked	ADJ
aji-178	260	3	vaccine	vaccine	NOUN
aji-178	260	4	construct	construct	VERB
aji-178	260	5	and	and	CCONJ
aji-178	260	6	tlr4	tlr4	NOUN
aji-178	260	7	receptor	receptor	NOUN
aji-178	260	8	can	can	AUX
aji-178	260	9	be	be	AUX
aji-178	260	10	seen	see	VERB
aji-178	260	11	in	in	ADP
aji-178	260	12	fig	fig	NOUN
aji-178	260	13	.	.	PUNCT
aji-178	261	1	4	4	NUM
aji-178	261	2	.	.	NOUN
aji-178	261	3	9	9	NUM
aji-178	261	4	.	.	X
aji-178	261	5	molecular	molecular	ADJ
aji-178	261	6	docking	docking	NOUN
aji-178	261	7	of	of	ADP
aji-178	261	8	vaccine	vaccine	NOUN
aji-178	261	9	construct	construct	VERB
aji-178	261	10	with	with	ADP
aji-178	261	11	mhc	mhc	PROPN
aji-178	261	12	i	i	PROPN
aji-178	261	13	:	:	PUNCT
aji-178	261	14	to	to	PART
aji-178	261	15	predict	predict	VERB
aji-178	261	16	the	the	DET
aji-178	261	17	active	active	ADJ
aji-178	261	18	and	and	CCONJ
aji-178	261	19	passive	passive	ADJ
aji-178	261	20	ligand	ligand	ADJ
aji-178	261	21	binding	bind	VERB
aji-178	261	22	sites	site	NOUN
aji-178	261	23	in	in	ADP
aji-178	261	24	the	the	DET
aji-178	261	25	refined	refined	ADJ
aji-178	261	26	tertiary	tertiary	ADJ
aji-178	261	27	vaccine	vaccine	NOUN
aji-178	261	28	structure	structure	VERB
aji-178	261	29	the	the	DET
aji-178	261	30	castp	castp	ADJ
aji-178	261	31	server	server	NOUN
aji-178	261	32	was	be	AUX
aji-178	261	33	used	use	VERB
aji-178	261	34	(	(	PUNCT
aji-178	261	35	martinot	martinot	ADV
aji-178	261	36	et	et	PROPN
aji-178	261	37	al	al	PROPN
aji-178	261	38	.	.	PROPN
aji-178	261	39	,	,	PUNCT
aji-178	261	40	2016	2016	NUM
aji-178	261	41	)	)	PUNCT
aji-178	261	42	.	.	PUNCT
aji-178	262	1	it	it	PRON
aji-178	262	2	predicted	predict	VERB
aji-178	262	3	60	60	NUM
aji-178	262	4	residues	residue	NOUN
aji-178	262	5	as	as	ADP
aji-178	262	6	active	active	ADJ
aji-178	262	7	ligandbinding	ligandbinde	VERB
aji-178	262	8	sites	site	NOUN
aji-178	262	9	and	and	CCONJ
aji-178	262	10	92	92	NUM
aji-178	262	11	residues	residue	NOUN
aji-178	262	12	as	as	ADP
aji-178	262	13	passive	passive	ADJ
aji-178	262	14	ligandbinding	ligandbinde	VERB
aji-178	262	15	sites	site	NOUN
aji-178	262	16	for	for	ADP
aji-178	262	17	mhc	mhc	PROPN
aji-178	262	18	i.	i.	PROPN
aji-178	262	19	the	the	PRON
aji-178	262	20	predicted	predict	VERB
aji-178	262	21	active	active	ADJ
aji-178	262	22	ligandbinding	ligandbinde	VERB
aji-178	262	23	sites	site	NOUN
aji-178	262	24	and	and	CCONJ
aji-178	262	25	passive	passive	ADJ
aji-178	262	26	ligand	ligand	NOUN
aji-178	262	27	-	-	PUNCT
aji-178	262	28	binding	bind	VERB
aji-178	262	29	sites	site	NOUN
aji-178	262	30	for	for	ADP
aji-178	262	31	vaccine	vaccine	NOUN
aji-178	262	32	construct	construct	NOUN
aji-178	262	33	was	be	AUX
aji-178	262	34	129	129	NUM
aji-178	262	35	,	,	PUNCT
aji-178	262	36	145	145	NUM
aji-178	262	37	residues	residue	NOUN
aji-178	262	38	respectively	respectively	ADV
aji-178	262	39	.	.	PUNCT
aji-178	263	1	for	for	ADP
aji-178	263	2	molecular	molecular	ADJ
aji-178	263	3	docking	docking	NOUN
aji-178	263	4	,	,	PUNCT
aji-178	263	5	the	the	DET
aji-178	263	6	refined	refined	ADJ
aji-178	263	7	vaccine	vaccine	NOUN
aji-178	263	8	construct	construct	VERB
aji-178	263	9	and	and	CCONJ
aji-178	263	10	mhc	mhc	PROPN
aji-178	263	11	i	i	PRON
aji-178	263	12	monomers	monomer	NOUN
aji-178	263	13	were	be	AUX
aji-178	263	14	uploaded	upload	VERB
aji-178	263	15	to	to	PART
aji-178	263	16	pydock	pydock	VERB
aji-178	263	17	web	web	NOUN
aji-178	263	18	server	server	NOUN
aji-178	263	19	.	.	PUNCT
aji-178	264	1	pydock	pydock	NOUN
aji-178	264	2	provided	provide	VERB
aji-178	264	3	top	top	ADJ
aji-178	264	4	10	10	NUM
aji-178	264	5	models	model	NOUN
aji-178	264	6	in	in	ADP
aji-178	264	7	which	which	DET
aji-178	264	8	model	model	NOUN
aji-178	264	9	1	1	NUM
aji-178	264	10	was	be	AUX
aji-178	264	11	selected	select	VERB
aji-178	264	12	.	.	PUNCT
aji-178	265	1	other	other	ADJ
aji-178	265	2	calculated	calculate	VERB
aji-178	265	3	parameters	parameter	NOUN
aji-178	265	4	are	be	AUX
aji-178	265	5	provided	provide	VERB
aji-178	265	6	in	in	ADP
aji-178	265	7	supplementary	supplementary	ADJ
aji-178	265	8	table	table	NOUN
aji-178	265	9	3	3	NUM
aji-178	265	10	.	.	PUNCT
aji-178	266	1	the	the	DET
aji-178	266	2	docked	docked	ADJ
aji-178	266	3	vaccine	vaccine	NOUN
aji-178	266	4	draft	draft	NOUN
aji-178	266	5	and	and	CCONJ
aji-178	266	6	mhc	mhc	PROPN
aji-178	266	7	i	i	PRON
aji-178	266	8	receptor	receptor	NOUN
aji-178	266	9	can	can	AUX
aji-178	266	10	be	be	AUX
aji-178	266	11	seen	see	VERB
aji-178	266	12	in	in	ADP
aji-178	266	13	fig	fig	NOUN
aji-178	266	14	.	.	PUNCT
aji-178	267	1	5	5	X
aji-178	267	2	.	.	X
aji-178	267	3	fig	fig	NOUN
aji-178	267	4	.	.	PUNCT
aji-178	268	1	5	5	X
aji-178	268	2	.	.	X
aji-178	268	3	molecular	molecular	ADJ
aji-178	268	4	docking	docking	NOUN
aji-178	268	5	of	of	ADP
aji-178	268	6	vaccine	vaccine	NOUN
aji-178	268	7	construct	construct	VERB
aji-178	268	8	and	and	CCONJ
aji-178	268	9	mhc	mhc	NOUN
aji-178	268	10	i	i	PRON
aji-178	268	11	ligand	ligand	VERB
aji-178	268	12	10	10	NUM
aji-178	268	13	.	.	PUNCT
aji-178	269	1	immune	immune	ADJ
aji-178	269	2	simulation	simulation	NOUN
aji-178	269	3	for	for	ADP
aji-178	269	4	vaccine	vaccine	NOUN
aji-178	269	5	efficacy	efficacy	NOUN
aji-178	269	6	the	the	DET
aji-178	269	7	immune	immune	ADJ
aji-178	269	8	responses	response	NOUN
aji-178	269	9	predicted	predict	VERB
aji-178	269	10	by	by	ADP
aji-178	269	11	the	the	DET
aji-178	269	12	cimmsim	cimmsim	NOUN
aji-178	269	13	server	server	NOUN
aji-178	269	14	indicated	indicate	VERB
aji-178	269	15	a	a	DET
aji-178	269	16	robust	robust	ADJ
aji-178	269	17	immunogenic	immunogenic	ADJ
aji-178	269	18	potential	potential	NOUN
aji-178	269	19	for	for	SCONJ
aji-178	269	20	the	the	DET
aji-178	269	21	vaccine	vaccine	NOUN
aji-178	269	22	construct	construct	VERB
aji-178	269	23	.	.	PUNCT
aji-178	270	1	the	the	DET
aji-178	270	2	vaccine	vaccine	NOUN
aji-178	270	3	elicited	elicit	VERB
aji-178	270	4	strong	strong	ADJ
aji-178	270	5	primary	primary	ADJ
aji-178	270	6	and	and	CCONJ
aji-178	270	7	secondary	secondary	ADJ
aji-178	270	8	immune	immune	ADJ
aji-178	270	9	responses	response	NOUN
aji-178	270	10	,	,	PUNCT
aji-178	270	11	as	as	SCONJ
aji-178	270	12	reflected	reflect	VERB
aji-178	270	13	in	in	ADP
aji-178	270	14	the	the	DET
aji-178	270	15	simulation	simulation	NOUN
aji-178	270	16	graphs	graph	NOUN
aji-178	270	17	.	.	PUNCT
aji-178	271	1	the	the	DET
aji-178	271	2	primary	primary	ADJ
aji-178	271	3	response	response	NOUN
aji-178	271	4	was	be	AUX
aji-178	271	5	characterized	characterize	VERB
aji-178	271	6	by	by	ADP
aji-178	271	7	an	an	DET
aji-178	271	8	naseema	naseema	NOUN
aji-178	271	9	;	;	PUNCT
aji-178	271	10	asian	asian	ADJ
aji-178	271	11	j.	j.	PROPN
aji-178	271	12	immunol	immunol	PROPN
aji-178	271	13	.	.	PROPN
aji-178	271	14	,	,	PUNCT
aji-178	271	15	vol	vol	NOUN
aji-178	271	16	.	.	PROPN
aji-178	271	17	8	8	NUM
aji-178	271	18	,	,	PUNCT
aji-178	271	19	no	no	INTJ
aji-178	271	20	.	.	NOUN
aji-178	271	21	1	1	NUM
aji-178	271	22	,	,	PUNCT
aji-178	271	23	pp	pp	ADJ
aji-178	271	24	.	.	PUNCT
aji-178	272	1	269	269	NUM
aji-178	272	2	-	-	SYM
aji-178	272	3	284	284	NUM
aji-178	272	4	,	,	PUNCT
aji-178	272	5	2025	2025	NUM
aji-178	272	6	;	;	PUNCT
aji-178	272	7	article	article	NOUN
aji-178	272	8	no.aji.147582	no.aji.147582	VERB
aji-178	272	9	276	276	NUM
aji-178	272	10	fig	fig	NOUN
aji-178	272	11	.	.	PUNCT
aji-178	273	1	6	6	NUM
aji-178	273	2	.	.	X
aji-178	273	3	in	in	ADP
aji-178	273	4	silico	silico	NOUN
aji-178	273	5	immune	immune	ADJ
aji-178	273	6	simulation	simulation	NOUN
aji-178	273	7	results	result	NOUN
aji-178	273	8	of	of	ADP
aji-178	273	9	vaccine	vaccine	NOUN
aji-178	273	10	construct	construct	VERB
aji-178	273	11	with	with	ADP
aji-178	273	12	tlr4	tlr4	NOUN
aji-178	273	13	ligand	ligand	NOUN
aji-178	273	14	using	use	VERB
aji-178	273	15	c	c	NOUN
aji-178	273	16	-	-	PUNCT
aji-178	273	17	immsim	immsim	NOUN
aji-178	273	18	web	web	NOUN
aji-178	273	19	server	server	NOUN
aji-178	273	20	(	(	PUNCT
aji-178	273	21	https://	https://	PROPN
aji-178	273	22	www	www	PROPN
aji-178	273	23	.	.	PROPN
aji-178	273	24	iac	iac	PROPN
aji-178	273	25	.	.	PROPN
aji-178	273	26	cnr	cnr	PROPN
aji-178	273	27	.	.	PUNCT
aji-178	274	1	it/	it/	X
aji-178	274	2	~filip	~filip	NUM
aji-178	274	3	po/	po/	PROPN
aji-178	274	4	proje	proje	PROPN
aji-178	274	5	cts	cts	PROPN
aji-178	274	6	/	/	SYM
aji-178	274	7	cimmsimonline	cimmsimonline	NOUN
aji-178	274	8	.	.	PUNCT
aji-178	275	1	html	html	NOUN
aji-178	275	2	)	)	PUNCT
aji-178	275	3	.	.	PUNCT
aji-178	276	1	(	(	PUNCT
aji-178	276	2	a	a	X
aji-178	276	3	)	)	PUNCT
aji-178	276	4	the	the	DET
aji-178	276	5	rapid	rapid	ADJ
aji-178	276	6	expansion	expansion	NOUN
aji-178	276	7	of	of	ADP
aji-178	276	8	b	b	NOUN
aji-178	276	9	-	-	PUNCT
aji-178	276	10	cells	cell	NOUN
aji-178	276	11	was	be	AUX
aji-178	276	12	accompanied	accompany	VERB
aji-178	276	13	by	by	ADP
aji-178	276	14	the	the	DET
aji-178	276	15	formation	formation	NOUN
aji-178	276	16	of	of	ADP
aji-178	276	17	memory	memory	NOUN
aji-178	276	18	b	b	NOUN
aji-178	276	19	-	-	PUNCT
aji-178	276	20	cells	cell	NOUN
aji-178	276	21	.	.	PUNCT
aji-178	277	1	(	(	PUNCT
aji-178	277	2	b	b	X
aji-178	277	3	)	)	PUNCT
aji-178	277	4	elevated	elevated	ADJ
aji-178	277	5	level	level	NOUN
aji-178	277	6	igg	igg	PROPN
aji-178	277	7	+	+	NOUN
aji-178	277	8	igm	igm	NOUN
aji-178	277	9	antibodies	antibodie	VERB
aji-178	277	10	in	in	ADP
aji-178	277	11	peripheral	peripheral	ADJ
aji-178	277	12	blood	blood	NOUN
aji-178	277	13	cells	cell	NOUN
aji-178	277	14	.	.	PUNCT
aji-178	278	1	(	(	PUNCT
aji-178	278	2	c	c	X
aji-178	278	3	)	)	PUNCT
aji-178	278	4	elevated	elevated	ADJ
aji-178	278	5	b	b	X
aji-178	278	6	-	-	PUNCT
aji-178	278	7	cell	cell	NOUN
aji-178	278	8	(	(	PUNCT
aji-178	278	9	active	active	ADJ
aji-178	278	10	)	)	PUNCT
aji-178	278	11	production	production	NOUN
aji-178	278	12	after	after	ADP
aji-178	278	13	a	a	DET
aji-178	278	14	lag	lag	NOUN
aji-178	278	15	phase	phase	NOUN
aji-178	278	16	of	of	ADP
aji-178	278	17	5–7	5–7	NUM
aji-178	278	18	days	day	NOUN
aji-178	278	19	after	after	ADP
aji-178	278	20	exposure	exposure	NOUN
aji-178	278	21	to	to	ADP
aji-178	278	22	the	the	DET
aji-178	278	23	vaccine	vaccine	NOUN
aji-178	278	24	chimera	chimera	NOUN
aji-178	278	25	.	.	PUNCT
aji-178	279	1	(	(	PUNCT
aji-178	279	2	d	d	X
aji-178	279	3	)	)	PUNCT
aji-178	279	4	high	high	ADJ
aji-178	279	5	level	level	NOUN
aji-178	279	6	of	of	ADP
aji-178	279	7	t	t	PROPN
aji-178	279	8	helper	helper	NOUN
aji-178	279	9	cells	cell	NOUN
aji-178	279	10	production	production	NOUN
aji-178	279	11	in	in	ADP
aji-178	279	12	response	response	NOUN
aji-178	279	13	to	to	ADP
aji-178	279	14	antigens	antigen	NOUN
aji-178	279	15	(	(	PUNCT
aji-178	279	16	e)active	e)active	PROPN
aji-178	279	17	t	t	PROPN
aji-178	279	18	helper	helper	NOUN
aji-178	279	19	cell	cell	NOUN
aji-178	279	20	population	population	NOUN
aji-178	279	21	within	within	ADP
aji-178	279	22	5	5	NUM
aji-178	279	23	days	day	NOUN
aji-178	279	24	of	of	ADP
aji-178	279	25	exposure	exposure	NOUN
aji-178	279	26	to	to	ADP
aji-178	279	27	antigen	antigen	PROPN
aji-178	279	28	.	.	PUNCT
aji-178	280	1	(	(	PUNCT
aji-178	280	2	f	f	X
aji-178	280	3	)	)	PUNCT
aji-178	280	4	constant	constant	ADJ
aji-178	280	5	production	production	NOUN
aji-178	280	6	of	of	ADP
aji-178	280	7	th1	th1	PROPN
aji-178	280	8	cells	cell	NOUN
aji-178	280	9	(	(	PUNCT
aji-178	280	10	g	g	NOUN
aji-178	280	11	)	)	PUNCT
aji-178	280	12	increased	increase	VERB
aji-178	280	13	level	level	NOUN
aji-178	280	14	of	of	ADP
aji-178	280	15	cytotoxic	cytotoxic	ADJ
aji-178	280	16	t	t	NOUN
aji-178	280	17	memory	memory	NOUN
aji-178	280	18	cells	cell	NOUN
aji-178	280	19	and	and	CCONJ
aji-178	280	20	(	(	PUNCT
aji-178	280	21	h	h	NOUN
aji-178	280	22	)	)	PUNCT
aji-178	280	23	evolution	evolution	NOUN
aji-178	280	24	of	of	ADP
aji-178	280	25	cytotoxic	cytotoxic	ADJ
aji-178	280	26	t	t	PROPN
aji-178	280	27	-	-	PUNCT
aji-178	280	28	cells	cell	NOUN
aji-178	280	29	naseema	naseema	NOUN
aji-178	280	30	;	;	PUNCT
aji-178	280	31	asian	asian	ADJ
aji-178	280	32	j.	j.	PROPN
aji-178	280	33	immunol	immunol	PROPN
aji-178	280	34	.	.	PROPN
aji-178	280	35	,	,	PUNCT
aji-178	280	36	vol	vol	NOUN
aji-178	280	37	.	.	PROPN
aji-178	280	38	8	8	NUM
aji-178	280	39	,	,	PUNCT
aji-178	280	40	no	no	INTJ
aji-178	280	41	.	.	NOUN
aji-178	280	42	1	1	NUM
aji-178	280	43	,	,	PUNCT
aji-178	280	44	pp	pp	ADJ
aji-178	280	45	.	.	PUNCT
aji-178	281	1	269	269	NUM
aji-178	281	2	-	-	SYM
aji-178	281	3	284	284	NUM
aji-178	281	4	,	,	PUNCT
aji-178	281	5	2025	2025	NUM
aji-178	281	6	;	;	PUNCT
aji-178	281	7	article	article	NOUN
aji-178	281	8	no.aji.147582	no.aji.147582	VERB
aji-178	281	9	277	277	NUM
aji-178	281	10	fig	fig	NOUN
aji-178	281	11	.	.	PUNCT
aji-178	282	1	7	7	X
aji-178	282	2	.	.	X
aji-178	282	3	in	in	ADP
aji-178	282	4	silico	silico	NOUN
aji-178	282	5	immune	immune	ADJ
aji-178	282	6	simulation	simulation	NOUN
aji-178	282	7	results	result	NOUN
aji-178	282	8	of	of	ADP
aji-178	282	9	vaccine	vaccine	NOUN
aji-178	282	10	construct	construct	VERB
aji-178	282	11	with	with	ADP
aji-178	282	12	mhc	mhc	PROPN
aji-178	282	13	i	i	PRON
aji-178	282	14	ligand	ligand	VERB
aji-178	282	15	using	use	VERB
aji-178	282	16	cimmsim	cimmsim	NOUN
aji-178	282	17	web	web	NOUN
aji-178	282	18	server	server	NOUN
aji-178	282	19	(	(	PUNCT
aji-178	282	20	https://	https://	PROPN
aji-178	282	21	www	www	PROPN
aji-178	282	22	.	.	PROPN
aji-178	282	23	iac	iac	PROPN
aji-178	282	24	.	.	PROPN
aji-178	282	25	cnr	cnr	PROPN
aji-178	282	26	.	.	PUNCT
aji-178	283	1	it/	it/	X
aji-178	283	2	~filip	~filip	NUM
aji-178	283	3	po/	po/	PROPN
aji-178	283	4	proje	proje	PROPN
aji-178	283	5	cts	cts	PROPN
aji-178	283	6	/	/	SYM
aji-178	283	7	cimmsimonline	cimmsimonline	NOUN
aji-178	283	8	.	.	PUNCT
aji-178	284	1	html	html	NOUN
aji-178	284	2	)	)	PUNCT
aji-178	284	3	.	.	PUNCT
aji-178	285	1	(	(	PUNCT
aji-178	285	2	a	a	X
aji-178	285	3	)	)	PUNCT
aji-178	285	4	the	the	DET
aji-178	285	5	rapid	rapid	ADJ
aji-178	285	6	proliferation	proliferation	NOUN
aji-178	285	7	of	of	ADP
aji-178	285	8	b	b	NOUN
aji-178	285	9	-	-	NOUN
aji-178	285	10	cell	cell	NOUN
aji-178	285	11	along	along	ADP
aji-178	285	12	with	with	ADP
aji-178	285	13	memory	memory	NOUN
aji-178	285	14	b	b	NOUN
aji-178	285	15	-	-	PUNCT
aji-178	285	16	cells	cell	NOUN
aji-178	285	17	.	.	PUNCT
aji-178	286	1	(	(	PUNCT
aji-178	286	2	b	b	X
aji-178	286	3	)	)	PUNCT
aji-178	286	4	high	high	ADJ
aji-178	286	5	level	level	NOUN
aji-178	286	6	of	of	ADP
aji-178	286	7	igg	igg	PROPN
aji-178	286	8	+	+	PROPN
aji-178	286	9	igm	igm	PROPN
aji-178	286	10	antibodies	antibodie	VERB
aji-178	286	11	in	in	ADP
aji-178	286	12	peripheral	peripheral	ADJ
aji-178	286	13	blood	blood	NOUN
aji-178	286	14	cells	cell	NOUN
aji-178	286	15	.	.	PUNCT
aji-178	287	1	(	(	PUNCT
aji-178	287	2	c	c	X
aji-178	287	3	)	)	PUNCT
aji-178	287	4	increased	increase	VERB
aji-178	287	5	b	b	NOUN
aji-178	287	6	-	-	PUNCT
aji-178	287	7	cell	cell	NOUN
aji-178	287	8	(	(	PUNCT
aji-178	287	9	active	active	ADJ
aji-178	287	10	)	)	PUNCT
aji-178	287	11	production	production	NOUN
aji-178	287	12	after	after	ADP
aji-178	287	13	a	a	DET
aji-178	287	14	lag	lag	NOUN
aji-178	287	15	phase	phase	NOUN
aji-178	287	16	of	of	ADP
aji-178	287	17	5–7	5–7	NUM
aji-178	287	18	days	day	NOUN
aji-178	287	19	after	after	ADP
aji-178	287	20	exposure	exposure	NOUN
aji-178	287	21	to	to	ADP
aji-178	287	22	the	the	DET
aji-178	287	23	vaccine	vaccine	NOUN
aji-178	287	24	chimera	chimera	NOUN
aji-178	287	25	.	.	PUNCT
aji-178	288	1	(	(	PUNCT
aji-178	288	2	d	d	X
aji-178	288	3	)	)	PUNCT
aji-178	288	4	elevated	elevated	ADJ
aji-178	288	5	level	level	NOUN
aji-178	288	6	of	of	ADP
aji-178	288	7	t	t	PROPN
aji-178	288	8	helper	helper	NOUN
aji-178	288	9	cells	cell	NOUN
aji-178	288	10	production	production	NOUN
aji-178	288	11	in	in	ADP
aji-178	288	12	response	response	NOUN
aji-178	288	13	to	to	ADP
aji-178	288	14	antigens	antigen	NOUN
aji-178	288	15	(	(	PUNCT
aji-178	288	16	e)active	e)active	PROPN
aji-178	288	17	t	t	PROPN
aji-178	288	18	helper	helper	NOUN
aji-178	288	19	cell	cell	NOUN
aji-178	288	20	population	population	NOUN
aji-178	288	21	within	within	ADP
aji-178	288	22	5	5	NUM
aji-178	288	23	days	day	NOUN
aji-178	288	24	of	of	ADP
aji-178	288	25	exposure	exposure	NOUN
aji-178	288	26	to	to	ADP
aji-178	288	27	antigen	antigen	PROPN
aji-178	288	28	.	.	PUNCT
aji-178	289	1	(	(	PUNCT
aji-178	289	2	f	f	X
aji-178	289	3	)	)	PUNCT
aji-178	289	4	constant	constant	ADJ
aji-178	289	5	production	production	NOUN
aji-178	289	6	of	of	ADP
aji-178	289	7	th1	th1	PROPN
aji-178	289	8	cells	cell	NOUN
aji-178	289	9	(	(	PUNCT
aji-178	289	10	g	g	NOUN
aji-178	289	11	)	)	PUNCT
aji-178	289	12	higher	high	ADJ
aji-178	289	13	level	level	NOUN
aji-178	289	14	of	of	ADP
aji-178	289	15	cytotoxic	cytotoxic	ADJ
aji-178	289	16	t	t	NOUN
aji-178	289	17	memory	memory	NOUN
aji-178	289	18	cells	cell	NOUN
aji-178	289	19	and	and	CCONJ
aji-178	289	20	(	(	PUNCT
aji-178	289	21	h	h	NOUN
aji-178	289	22	)	)	PUNCT
aji-178	289	23	evolution	evolution	NOUN
aji-178	289	24	of	of	ADP
aji-178	289	25	cytotoxic	cytotoxic	ADJ
aji-178	289	26	t	t	PROPN
aji-178	289	27	-	-	PUNCT
aji-178	289	28	cells	cell	NOUN
aji-178	289	29	naseema	naseema	NOUN
aji-178	289	30	;	;	PUNCT
aji-178	289	31	asian	asian	ADJ
aji-178	289	32	j.	j.	PROPN
aji-178	289	33	immunol	immunol	PROPN
aji-178	289	34	.	.	PROPN
aji-178	289	35	,	,	PUNCT
aji-178	289	36	vol	vol	NOUN
aji-178	289	37	.	.	PROPN
aji-178	289	38	8	8	NUM
aji-178	289	39	,	,	PUNCT
aji-178	289	40	no	no	INTJ
aji-178	289	41	.	.	NOUN
aji-178	289	42	1	1	NUM
aji-178	289	43	,	,	PUNCT
aji-178	289	44	pp	pp	ADJ
aji-178	289	45	.	.	PUNCT
aji-178	290	1	269	269	NUM
aji-178	290	2	-	-	SYM
aji-178	290	3	284	284	NUM
aji-178	290	4	,	,	PUNCT
aji-178	290	5	2025	2025	NUM
aji-178	290	6	;	;	PUNCT
aji-178	290	7	article	article	NOUN
aji-178	290	8	no.aji.147582	no.aji.147582	VERB
aji-178	290	9	278	278	NUM
aji-178	290	10	increase	increase	NOUN
aji-178	290	11	in	in	ADP
aji-178	290	12	igm	igm	NOUN
aji-178	290	13	antibody	antibody	NOUN
aji-178	290	14	levels	level	NOUN
aji-178	290	15	following	follow	VERB
aji-178	290	16	a	a	DET
aji-178	290	17	lag	lag	NOUN
aji-178	290	18	period	period	NOUN
aji-178	290	19	of	of	ADP
aji-178	290	20	5–7	5–7	NUM
aji-178	290	21	days	day	NOUN
aji-178	290	22	post	post	ADJ
aji-178	290	23	-	-	ADJ
aji-178	290	24	antigen	antigen	ADJ
aji-178	290	25	exposure	exposure	NOUN
aji-178	290	26	.	.	PUNCT
aji-178	291	1	the	the	DET
aji-178	291	2	secondary	secondary	ADJ
aji-178	291	3	response	response	NOUN
aji-178	291	4	demonstrated	demonstrate	VERB
aji-178	291	5	enhanced	enhance	VERB
aji-178	291	6	bcell	bcell	NOUN
aji-178	291	7	proliferation	proliferation	NOUN
aji-178	291	8	along	along	ADP
aji-178	291	9	with	with	ADP
aji-178	291	10	elevated	elevated	ADJ
aji-178	291	11	levels	level	NOUN
aji-178	291	12	of	of	ADP
aji-178	291	13	igg+igm	igg+igm	PROPN
aji-178	291	14	,	,	PUNCT
aji-178	291	15	igm	igm	PROPN
aji-178	291	16	,	,	PUNCT
aji-178	291	17	and	and	CCONJ
aji-178	291	18	igg1+igg2	igg1+igg2	PROPN
aji-178	291	19	antibodies	antibodie	VERB
aji-178	291	20	.	.	PUNCT
aji-178	292	1	in	in	ADP
aji-178	292	2	addition	addition	NOUN
aji-178	292	3	to	to	ADP
aji-178	292	4	promoting	promote	VERB
aji-178	292	5	significant	significant	ADJ
aji-178	292	6	b	b	NOUN
aji-178	292	7	-	-	PUNCT
aji-178	292	8	cell	cell	NOUN
aji-178	292	9	proliferation	proliferation	NOUN
aji-178	292	10	and	and	CCONJ
aji-178	292	11	memory	memory	NOUN
aji-178	292	12	b	b	NOUN
aji-178	292	13	-	-	PUNCT
aji-178	292	14	cell	cell	NOUN
aji-178	292	15	formation	formation	NOUN
aji-178	292	16	,	,	PUNCT
aji-178	292	17	the	the	DET
aji-178	292	18	vaccine	vaccine	NOUN
aji-178	292	19	construct	construct	VERB
aji-178	292	20	induced	induce	VERB
aji-178	292	21	strong	strong	ADJ
aji-178	292	22	cytotoxic	cytotoxic	ADJ
aji-178	292	23	and	and	CCONJ
aji-178	292	24	helper	helper	NOUN
aji-178	292	25	t	t	PROPN
aji-178	292	26	-	-	PUNCT
aji-178	292	27	cell	cell	NOUN
aji-178	292	28	activity	activity	NOUN
aji-178	292	29	and	and	CCONJ
aji-178	292	30	maintained	maintain	VERB
aji-178	292	31	elevated	elevated	ADJ
aji-178	292	32	ifn	ifn	PROPN
aji-178	292	33	-	-	PUNCT
aji-178	292	34	γ	γ	NOUN
aji-178	292	35	levels	level	NOUN
aji-178	292	36	for	for	ADP
aji-178	292	37	an	an	DET
aji-178	292	38	extended	extended	ADJ
aji-178	292	39	duration	duration	NOUN
aji-178	292	40	.	.	PUNCT
aji-178	293	1	4	4	X
aji-178	293	2	.	.	X
aji-178	293	3	discussion	discussion	NOUN
aji-178	293	4	mycobacterium	mycobacterium	NOUN
aji-178	293	5	tuberculosis	tuberculosis	NOUN
aji-178	293	6	(	(	PUNCT
aji-178	293	7	m.	m.	NOUN
aji-178	293	8	tb	tb	NOUN
aji-178	293	9	)	)	PUNCT
aji-178	293	10	is	be	AUX
aji-178	293	11	the	the	DET
aji-178	293	12	second	second	ADJ
aji-178	293	13	deadliest	deadly	ADJ
aji-178	293	14	disease	disease	NOUN
aji-178	293	15	which	which	PRON
aji-178	293	16	can	can	AUX
aji-178	293	17	actively	actively	ADV
aji-178	293	18	tackle	tackle	VERB
aji-178	293	19	antibiotic	antibiotic	ADJ
aji-178	293	20	treatment	treatment	NOUN
aji-178	293	21	(	(	PUNCT
aji-178	293	22	mehla	mehla	PROPN
aji-178	293	23	&	&	CCONJ
aji-178	293	24	ramana	ramana	PROPN
aji-178	293	25	,	,	PUNCT
aji-178	293	26	2016	2016	NUM
aji-178	293	27	)	)	PUNCT
aji-178	293	28	.	.	PUNCT
aji-178	294	1	“	"	PUNCT
aji-178	294	2	globally	globally	ADV
aji-178	294	3	,	,	PUNCT
aji-178	294	4	there	there	PRON
aji-178	294	5	is	be	VERB
aji-178	294	6	an	an	DET
aji-178	294	7	urge	urge	NOUN
aji-178	294	8	to	to	PART
aji-178	294	9	develop	develop	VERB
aji-178	294	10	vaccines	vaccine	NOUN
aji-178	294	11	and	and	CCONJ
aji-178	294	12	treatment	treatment	NOUN
aji-178	294	13	for	for	ADP
aji-178	294	14	tb	tb	NOUN
aji-178	294	15	,	,	PUNCT
aji-178	294	16	because	because	SCONJ
aji-178	294	17	recently	recently	ADV
aji-178	294	18	it	it	PRON
aji-178	294	19	has	have	AUX
aji-178	294	20	been	be	AUX
aji-178	294	21	identified	identify	VERB
aji-178	294	22	that	that	SCONJ
aji-178	294	23	the	the	DET
aji-178	294	24	well	well	ADV
aji-178	294	25	-	-	PUNCT
aji-178	294	26	known	know	VERB
aji-178	294	27	and	and	CCONJ
aji-178	294	28	only	only	ADV
aji-178	294	29	licensed	licensed	ADJ
aji-178	294	30	anti	anti	ADJ
aji-178	294	31	-	-	ADJ
aji-178	294	32	tuberculosis	tuberculosis	ADJ
aji-178	294	33	vaccine	vaccine	NOUN
aji-178	294	34	called	call	VERB
aji-178	294	35	bcg	bcg	PROPN
aji-178	294	36	is	be	AUX
aji-178	294	37	no	no	ADV
aji-178	294	38	longer	long	ADV
aji-178	294	39	effective	effective	ADJ
aji-178	294	40	in	in	ADP
aji-178	294	41	adults	adult	NOUN
aji-178	294	42	”	"	PUNCT
aji-178	294	43	(	(	PUNCT
aji-178	294	44	mustafa	mustafa	PROPN
aji-178	294	45	,	,	PUNCT
aji-178	294	46	2002	2002	NUM
aji-178	294	47	)	)	PUNCT
aji-178	294	48	.	.	PUNCT
aji-178	295	1	“	"	PUNCT
aji-178	295	2	in	in	ADP
aji-178	295	3	light	light	NOUN
aji-178	295	4	of	of	ADP
aji-178	295	5	ever	ever	ADV
aji-178	295	6	-	-	PUNCT
aji-178	295	7	growing	grow	VERB
aji-178	295	8	drug	drug	NOUN
aji-178	295	9	resistance	resistance	NOUN
aji-178	295	10	and	and	CCONJ
aji-178	295	11	adverse	adverse	ADJ
aji-178	295	12	effects	effect	NOUN
aji-178	295	13	associated	associate	VERB
aji-178	295	14	with	with	ADP
aji-178	295	15	anti	anti	ADJ
aji-178	295	16	-	-	ADJ
aji-178	295	17	tb	tb	ADJ
aji-178	295	18	drugs	drug	NOUN
aji-178	295	19	such	such	ADJ
aji-178	295	20	as	as	ADP
aji-178	295	21	ototoxicity	ototoxicity	NOUN
aji-178	295	22	,	,	PUNCT
aji-178	295	23	hepatotoxicity	hepatotoxicity	NOUN
aji-178	295	24	,	,	PUNCT
aji-178	295	25	neuropsychiatricevents	neuropsychiatricevent	NOUN
aji-178	295	26	,	,	PUNCT
aji-178	295	27	hyperuricemia	hyperuricemia	ADV
aji-178	295	28	,	,	PUNCT
aji-178	295	29	gastrointestinal	gastrointestinal	ADJ
aji-178	295	30	disturbance	disturbance	NOUN
aji-178	295	31	,	,	PUNCT
aji-178	295	32	vision	vision	NOUN
aji-178	295	33	loss	loss	NOUN
aji-178	295	34	,	,	PUNCT
aji-178	295	35	skin	skin	NOUN
aji-178	295	36	pigmentation	pigmentation	NOUN
aji-178	295	37	etc	etc	X
aji-178	295	38	,	,	PUNCT
aji-178	295	39	a	a	DET
aji-178	295	40	safe	safe	ADJ
aji-178	295	41	and	and	CCONJ
aji-178	295	42	efficacious	efficacious	ADJ
aji-178	295	43	vaccine	vaccine	NOUN
aji-178	295	44	could	could	AUX
aji-178	295	45	be	be	AUX
aji-178	295	46	an	an	DET
aji-178	295	47	imperious	imperious	ADJ
aji-178	295	48	arsenal	arsenal	NOUN
aji-178	295	49	against	against	ADP
aji-178	295	50	this	this	DET
aji-178	295	51	lethal	lethal	ADJ
aji-178	295	52	disease	disease	NOUN
aji-178	295	53	”	"	PUNCT
aji-178	295	54	(	(	PUNCT
aji-178	295	55	nagpal	nagpal	X
aji-178	295	56	et	et	PROPN
aji-178	295	57	al	al	PROPN
aji-178	295	58	.	.	PROPN
aji-178	295	59	,	,	PUNCT
aji-178	295	60	2020	2020	NUM
aji-178	295	61	)	)	PUNCT
aji-178	295	62	.	.	PUNCT
aji-178	296	1	“	"	PUNCT
aji-178	296	2	the	the	DET
aji-178	296	3	different	different	ADJ
aji-178	296	4	protocols	protocol	NOUN
aji-178	296	5	followed	follow	VERB
aji-178	296	6	by	by	ADP
aji-178	296	7	various	various	ADJ
aji-178	296	8	laboratories	laboratory	NOUN
aji-178	296	9	over	over	ADP
aji-178	296	10	the	the	DET
aji-178	296	11	last	last	ADJ
aji-178	296	12	few	few	ADJ
aji-178	296	13	years	year	NOUN
aji-178	296	14	for	for	ADP
aji-178	296	15	bcg	bcg	NOUN
aji-178	296	16	culture	culture	NOUN
aji-178	296	17	showed	show	VERB
aji-178	296	18	different	different	ADJ
aji-178	296	19	level	level	NOUN
aji-178	296	20	of	of	ADP
aji-178	296	21	divergence	divergence	NOUN
aji-178	296	22	in	in	ADP
aji-178	296	23	the	the	DET
aji-178	296	24	efficacy	efficacy	NOUN
aji-178	296	25	of	of	ADP
aji-178	296	26	bcg	bcg	PROPN
aji-178	296	27	vaccine	vaccine	NOUN
aji-178	296	28	”	"	PUNCT
aji-178	296	29	(	(	PUNCT
aji-178	296	30	lee	lee	PROPN
aji-178	296	31	et	et	PROPN
aji-178	296	32	al	al	PROPN
aji-178	296	33	.	.	PROPN
aji-178	296	34	,	,	PUNCT
aji-178	296	35	2014	2014	NUM
aji-178	296	36	)	)	PUNCT
aji-178	296	37	.	.	PUNCT
aji-178	297	1	“	"	PUNCT
aji-178	297	2	several	several	ADJ
aji-178	297	3	reports	report	NOUN
aji-178	297	4	suggest	suggest	VERB
aji-178	297	5	that	that	SCONJ
aji-178	297	6	bcg	bcg	PROPN
aji-178	297	7	grown	grow	VERB
aji-178	297	8	in	in	ADP
aji-178	297	9	sauton	sauton	NOUN
aji-178	297	10	medium	medium	NOUN
aji-178	297	11	elicits	elicit	VERB
aji-178	297	12	a	a	DET
aji-178	297	13	stronger	strong	ADJ
aji-178	297	14	immune	immune	ADJ
aji-178	297	15	response	response	NOUN
aji-178	297	16	than	than	SCONJ
aji-178	297	17	bcg	bcg	PROPN
aji-178	297	18	cultured	culture	VERB
aji-178	297	19	in	in	ADP
aji-178	297	20	middlebrook	middlebrook	PROPN
aji-178	297	21	7h9	7h9	NUM
aji-178	297	22	medium	medium	NOUN
aji-178	297	23	”	"	PUNCT
aji-178	297	24	(	(	PUNCT
aji-178	297	25	fleri	fleri	X
aji-178	297	26	et	et	NOUN
aji-178	297	27	al	al	PROPN
aji-178	297	28	.	.	PROPN
aji-178	297	29	,	,	PUNCT
aji-178	297	30	2017	2017	NUM
aji-178	297	31	)	)	PUNCT
aji-178	297	32	.	.	PUNCT
aji-178	298	1	“	"	PUNCT
aji-178	298	2	out	out	ADP
aji-178	298	3	of	of	ADP
aji-178	298	4	the	the	DET
aji-178	298	5	numerous	numerous	ADJ
aji-178	298	6	anti	anti	ADJ
aji-178	298	7	-	-	ADJ
aji-178	298	8	tuberculosis	tuberculosis	ADJ
aji-178	298	9	vaccines	vaccine	NOUN
aji-178	298	10	under	under	ADP
aji-178	298	11	development	development	NOUN
aji-178	298	12	,	,	PUNCT
aji-178	298	13	only	only	ADV
aji-178	298	14	vmp1002	vmp1002	NOUN
aji-178	298	15	,	,	PUNCT
aji-178	298	16	mip	mip	PROPN
aji-178	298	17	,	,	PUNCT
aji-178	298	18	and	and	CCONJ
aji-178	298	19	m.	m.	NOUN
aji-178	298	20	vaccae	vaccae	PROPN
aji-178	298	21	have	have	AUX
aji-178	298	22	advanced	advance	VERB
aji-178	298	23	to	to	PART
aji-178	298	24	phase	phase	VERB
aji-178	298	25	iii	iii	NUM
aji-178	298	26	trials	trial	NOUN
aji-178	298	27	,	,	PUNCT
aji-178	298	28	with	with	ADP
aji-178	298	29	plans	plan	NOUN
aji-178	298	30	to	to	PART
aji-178	298	31	use	use	VERB
aji-178	298	32	them	they	PRON
aji-178	298	33	as	as	ADP
aji-178	298	34	boosters	booster	NOUN
aji-178	298	35	for	for	ADP
aji-178	298	36	bcg	bcg	NOUN
aji-178	298	37	in	in	ADP
aji-178	298	38	the	the	DET
aji-178	298	39	future	future	NOUN
aji-178	298	40	.	.	PUNCT
aji-178	299	1	in	in	ADP
aji-178	299	2	recent	recent	ADJ
aji-178	299	3	years	year	NOUN
aji-178	299	4	,	,	PUNCT
aji-178	299	5	the	the	DET
aji-178	299	6	use	use	NOUN
aji-178	299	7	of	of	ADP
aji-178	299	8	immunoinformatics	immunoinformatic	NOUN
aji-178	299	9	has	have	AUX
aji-178	299	10	rapidly	rapidly	ADV
aji-178	299	11	gained	gain	VERB
aji-178	299	12	attention	attention	NOUN
aji-178	299	13	for	for	ADP
aji-178	299	14	drug	drug	NOUN
aji-178	299	15	and	and	CCONJ
aji-178	299	16	vaccine	vaccine	NOUN
aji-178	299	17	development	development	NOUN
aji-178	299	18	compared	compare	VERB
aji-178	299	19	to	to	ADP
aji-178	299	20	traditional	traditional	ADJ
aji-178	299	21	approaches	approach	NOUN
aji-178	299	22	”	"	PUNCT
aji-178	299	23	(	(	PUNCT
aji-178	299	24	jung	jung	PROPN
aji-178	299	25	et	et	PROPN
aji-178	299	26	al	al	PROPN
aji-178	299	27	.	.	PROPN
aji-178	299	28	,	,	PUNCT
aji-178	299	29	2011	2011	NUM
aji-178	299	30	)	)	PUNCT
aji-178	299	31	.	.	PUNCT
aji-178	300	1	in	in	ADP
aji-178	300	2	this	this	DET
aji-178	300	3	study	study	NOUN
aji-178	300	4	,	,	PUNCT
aji-178	300	5	a	a	DET
aji-178	300	6	multi	multi	ADJ
aji-178	300	7	-	-	ADJ
aji-178	300	8	epitope	epitope	ADJ
aji-178	300	9	vaccine	vaccine	NOUN
aji-178	300	10	was	be	AUX
aji-178	300	11	designed	design	VERB
aji-178	300	12	using	use	VERB
aji-178	300	13	experimentally	experimentally	ADV
aji-178	300	14	validated	validate	VERB
aji-178	300	15	immunogenic	immunogenic	ADJ
aji-178	300	16	exosome	exosome	NOUN
aji-178	300	17	vesicle	vesicle	NOUN
aji-178	300	18	-	-	PUNCT
aji-178	300	19	based	base	VERB
aji-178	300	20	antigens	antigen	NOUN
aji-178	300	21	in	in	ADP
aji-178	300	22	response	response	NOUN
aji-178	300	23	to	to	ADP
aji-178	300	24	the	the	DET
aji-178	300	25	global	global	ADJ
aji-178	300	26	crisis	crisis	NOUN
aji-178	300	27	(	(	PUNCT
aji-178	300	28	carmona	carmona	PROPN
aji-178	300	29	et	et	PROPN
aji-178	300	30	al	al	PROPN
aji-178	300	31	.	.	PROPN
aji-178	300	32	,	,	PUNCT
aji-178	300	33	2013	2013	NUM
aji-178	300	34	)	)	PUNCT
aji-178	300	35	.	.	PUNCT
aji-178	301	1	“	"	PUNCT
aji-178	301	2	to	to	PART
aji-178	301	3	assess	assess	VERB
aji-178	301	4	their	their	PRON
aji-178	301	5	immune	immune	NOUN
aji-178	301	6	-	-	PUNCT
aji-178	301	7	stimulating	stimulate	VERB
aji-178	301	8	potential	potential	NOUN
aji-178	301	9	,	,	PUNCT
aji-178	301	10	these	these	DET
aji-178	301	11	antigens	antigen	NOUN
aji-178	301	12	were	be	AUX
aji-178	301	13	examined	examine	VERB
aji-178	301	14	for	for	ADP
aji-178	301	15	b	b	NOUN
aji-178	301	16	-	-	PUNCT
aji-178	301	17	cell	cell	NOUN
aji-178	301	18	,	,	PUNCT
aji-178	301	19	htl	htl	PROPN
aji-178	301	20	,	,	PUNCT
aji-178	301	21	and	and	CCONJ
aji-178	301	22	ctl	ctl	PROPN
aji-178	301	23	epitopes	epitope	NOUN
aji-178	301	24	,	,	PUNCT
aji-178	301	25	corresponding	correspond	VERB
aji-178	301	26	to	to	ADP
aji-178	301	27	humoral	humoral	ADJ
aji-178	301	28	,	,	PUNCT
aji-178	301	29	innate	innate	ADJ
aji-178	301	30	,	,	PUNCT
aji-178	301	31	and	and	CCONJ
aji-178	301	32	cell	cell	NOUN
aji-178	301	33	-	-	PUNCT
aji-178	301	34	mediated	mediate	VERB
aji-178	301	35	responses	response	NOUN
aji-178	301	36	.	.	PUNCT
aji-178	302	1	additionally	additionally	ADV
aji-178	302	2	,	,	PUNCT
aji-178	302	3	all	all	DET
aji-178	302	4	selected	select	VERB
aji-178	302	5	epitopes	epitope	NOUN
aji-178	302	6	were	be	AUX
aji-178	302	7	evaluated	evaluate	VERB
aji-178	302	8	for	for	ADP
aji-178	302	9	nontoxicity	nontoxicity	ADJ
aji-178	302	10	,	,	PUNCT
aji-178	302	11	non	non	ADJ
aji-178	302	12	-	-	NOUN
aji-178	302	13	allergenicity	allergenicity	NOUN
aji-178	302	14	,	,	PUNCT
aji-178	302	15	and	and	CCONJ
aji-178	302	16	ifn	ifn	PROPN
aji-178	302	17	-	-	PUNCT
aji-178	302	18	γ	γ	NOUN
aji-178	302	19	induction	induction	NOUN
aji-178	302	20	.	.	PUNCT
aji-178	303	1	the	the	DET
aji-178	303	2	chosen	choose	VERB
aji-178	303	3	epitopes	epitope	NOUN
aji-178	303	4	were	be	AUX
aji-178	303	5	linked	link	VERB
aji-178	303	6	using	use	VERB
aji-178	303	7	appropriate	appropriate	ADJ
aji-178	303	8	peptide	peptide	NOUN
aji-178	303	9	linkers	linker	NOUN
aji-178	303	10	,	,	PUNCT
aji-178	303	11	and	and	CCONJ
aji-178	303	12	the	the	DET
aji-178	303	13	tlr4	tlr4	NOUN
aji-178	303	14	agonist	agonist	NOUN
aji-178	303	15	peptide	peptide	NOUN
aji-178	303	16	rpfe	rpfe	PROPN
aji-178	303	17	was	be	AUX
aji-178	303	18	attached	attach	VERB
aji-178	303	19	to	to	ADP
aji-178	303	20	the	the	DET
aji-178	303	21	nterminal	nterminal	NOUN
aji-178	303	22	of	of	ADP
aji-178	303	23	the	the	DET
aji-178	303	24	construct	construct	NOUN
aji-178	303	25	to	to	PART
aji-178	303	26	serve	serve	VERB
aji-178	303	27	as	as	ADP
aji-178	303	28	an	an	DET
aji-178	303	29	adjuvant	adjuvant	NOUN
aji-178	303	30	and	and	CCONJ
aji-178	303	31	enhance	enhance	VERB
aji-178	303	32	the	the	DET
aji-178	303	33	immune	immune	ADJ
aji-178	303	34	response	response	NOUN
aji-178	303	35	.	.	PUNCT
aji-178	304	1	during	during	ADP
aji-178	304	2	m.	m.	NOUN
aji-178	304	3	tuberculosis	tuberculosis	NOUN
aji-178	304	4	infection	infection	NOUN
aji-178	304	5	,	,	PUNCT
aji-178	304	6	both	both	PRON
aji-178	304	7	tlr2	tlr2	PROPN
aji-178	304	8	and	and	CCONJ
aji-178	304	9	tlr4	tlr4	NOUN
aji-178	304	10	are	be	AUX
aji-178	304	11	involved	involve	VERB
aji-178	304	12	in	in	ADP
aji-178	304	13	pathogen	pathogen	NOUN
aji-178	304	14	recognition	recognition	NOUN
aji-178	304	15	,	,	PUNCT
aji-178	304	16	activating	activate	VERB
aji-178	304	17	macrophages	macrophage	NOUN
aji-178	304	18	and	and	CCONJ
aji-178	304	19	dendritic	dendritic	ADJ
aji-178	304	20	cells	cell	NOUN
aji-178	304	21	and	and	CCONJ
aji-178	304	22	influencing	influence	VERB
aji-178	304	23	both	both	CCONJ
aji-178	304	24	innate	innate	ADJ
aji-178	304	25	and	and	CCONJ
aji-178	304	26	adaptive	adaptive	ADJ
aji-178	304	27	immunity	immunity	NOUN
aji-178	304	28	”	"	PUNCT
aji-178	304	29	(	(	PUNCT
aji-178	304	30	hart	hart	PROPN
aji-178	304	31	et	et	PROPN
aji-178	304	32	al	al	PROPN
aji-178	304	33	.	.	PROPN
aji-178	304	34	,	,	PUNCT
aji-178	304	35	1987	1987	NUM
aji-178	304	36	)	)	PUNCT
aji-178	304	37	.	.	PUNCT
aji-178	305	1	“	"	PUNCT
aji-178	305	2	tlr4	tlr4	NOUN
aji-178	305	3	was	be	AUX
aji-178	305	4	selected	select	VERB
aji-178	305	5	as	as	ADP
aji-178	305	6	the	the	DET
aji-178	305	7	target	target	NOUN
aji-178	305	8	receptor	receptor	NOUN
aji-178	305	9	for	for	ADP
aji-178	305	10	the	the	DET
aji-178	305	11	vaccine	vaccine	NOUN
aji-178	305	12	construct	construct	VERB
aji-178	305	13	due	due	ADP
aji-178	305	14	to	to	ADP
aji-178	305	15	its	its	PRON
aji-178	305	16	critical	critical	ADJ
aji-178	305	17	role	role	NOUN
aji-178	305	18	in	in	ADP
aji-178	305	19	infection	infection	NOUN
aji-178	305	20	;	;	PUNCT
aji-178	305	21	tlr4	tlr4	NOUN
aji-178	305	22	-	-	PUNCT
aji-178	305	23	deficient	deficient	ADJ
aji-178	305	24	mice	mouse	NOUN
aji-178	305	25	show	show	VERB
aji-178	305	26	lower	low	ADJ
aji-178	305	27	survival	survival	NOUN
aji-178	305	28	rates	rate	NOUN
aji-178	305	29	and	and	CCONJ
aji-178	305	30	higher	high	ADJ
aji-178	305	31	bacterial	bacterial	ADJ
aji-178	305	32	loads	load	NOUN
aji-178	305	33	compared	compare	VERB
aji-178	305	34	to	to	ADP
aji-178	305	35	tlr2	tlr2	NOUN
aji-178	305	36	-	-	PUNCT
aji-178	305	37	deficient	deficient	ADJ
aji-178	305	38	mice	mouse	NOUN
aji-178	305	39	when	when	SCONJ
aji-178	305	40	infected	infect	VERB
aji-178	305	41	with	with	ADP
aji-178	305	42	m.	m.	NOUN
aji-178	305	43	tuberculosis	tuberculosis	NOUN
aji-178	305	44	”	"	PUNCT
aji-178	305	45	(	(	PUNCT
aji-178	305	46	kim	kim	PROPN
aji-178	305	47	et	et	PROPN
aji-178	305	48	al	al	PROPN
aji-178	305	49	.	.	PROPN
aji-178	305	50	,	,	PUNCT
aji-178	305	51	2018	2018	NUM
aji-178	305	52	)	)	PUNCT
aji-178	305	53	.	.	PUNCT
aji-178	306	1	five	five	NUM
aji-178	306	2	vaccine	vaccine	NOUN
aji-178	306	3	constructs	construct	NOUN
aji-178	306	4	were	be	AUX
aji-178	306	5	created	create	VERB
aji-178	306	6	and	and	CCONJ
aji-178	306	7	evaluated	evaluate	VERB
aji-178	306	8	using	use	VERB
aji-178	306	9	homology	homology	NOUN
aji-178	306	10	modeling	modeling	NOUN
aji-178	306	11	.	.	PUNCT
aji-178	307	1	one	one	NUM
aji-178	307	2	construct	construct	NOUN
aji-178	307	3	was	be	AUX
aji-178	307	4	refined	refine	VERB
aji-178	307	5	in	in	ADP
aji-178	307	6	3d	3d	NUM
aji-178	307	7	and	and	CCONJ
aji-178	307	8	docked	dock	VERB
aji-178	307	9	with	with	ADP
aji-178	307	10	monomeric	monomeric	ADJ
aji-178	307	11	tlr4	tlr4	NOUN
aji-178	307	12	,	,	PUNCT
aji-178	307	13	producing	produce	VERB
aji-178	307	14	a	a	DET
aji-178	307	15	complex	complex	NOUN
aji-178	307	16	with	with	ADP
aji-178	307	17	favorable	favorable	ADJ
aji-178	307	18	binding	binding	ADJ
aji-178	307	19	energy	energy	NOUN
aji-178	307	20	and	and	CCONJ
aji-178	307	21	stable	stable	ADJ
aji-178	307	22	structure	structure	NOUN
aji-178	307	23	.	.	PUNCT
aji-178	308	1	finally	finally	ADV
aji-178	308	2	,	,	PUNCT
aji-178	308	3	an	an	DET
aji-178	308	4	immune	immune	ADJ
aji-178	308	5	simulation	simulation	NOUN
aji-178	308	6	study	study	NOUN
aji-178	308	7	,	,	PUNCT
aji-178	308	8	modeling	model	VERB
aji-178	308	9	the	the	DET
aji-178	308	10	innate	innate	ADJ
aji-178	308	11	immune	immune	ADJ
aji-178	308	12	network	network	NOUN
aji-178	308	13	including	include	VERB
aji-178	308	14	t	t	PROPN
aji-178	308	15	and	and	CCONJ
aji-178	308	16	b	b	NOUN
aji-178	308	17	cells	cell	NOUN
aji-178	308	18	,	,	PUNCT
aji-178	308	19	was	be	AUX
aji-178	308	20	performed	perform	VERB
aji-178	308	21	to	to	PART
aji-178	308	22	evaluate	evaluate	VERB
aji-178	308	23	both	both	DET
aji-178	308	24	humoral	humoral	ADJ
aji-178	308	25	and	and	CCONJ
aji-178	308	26	cellular	cellular	ADJ
aji-178	308	27	responses	response	NOUN
aji-178	308	28	.	.	PUNCT
aji-178	309	1	the	the	DET
aji-178	309	2	results	result	NOUN
aji-178	309	3	indicate	indicate	VERB
aji-178	309	4	that	that	SCONJ
aji-178	309	5	the	the	DET
aji-178	309	6	designed	design	VERB
aji-178	309	7	multiepitope	multiepitope	NOUN
aji-178	309	8	vaccine	vaccine	NOUN
aji-178	309	9	elicits	elicit	VERB
aji-178	309	10	a	a	DET
aji-178	309	11	strong	strong	ADJ
aji-178	309	12	and	and	CCONJ
aji-178	309	13	consistent	consistent	ADJ
aji-178	309	14	immune	immune	ADJ
aji-178	309	15	response	response	NOUN
aji-178	309	16	.	.	PUNCT
aji-178	310	1	5	5	X
aji-178	310	2	.	.	X
aji-178	310	3	conclusion	conclusion	VERB
aji-178	310	4	our	our	PRON
aji-178	310	5	results	result	NOUN
aji-178	310	6	show	show	VERB
aji-178	310	7	that	that	SCONJ
aji-178	310	8	the	the	DET
aji-178	310	9	vaccine	vaccine	NOUN
aji-178	310	10	candidate	candidate	NOUN
aji-178	310	11	possesses	possess	VERB
aji-178	310	12	suitable	suitable	ADJ
aji-178	310	13	physicochemical	physicochemical	ADJ
aji-178	310	14	qualities	quality	NOUN
aji-178	310	15	,	,	PUNCT
aji-178	310	16	a	a	DET
aji-178	310	17	stable	stable	ADJ
aji-178	310	18	structure	structure	NOUN
aji-178	310	19	,	,	PUNCT
aji-178	310	20	and	and	CCONJ
aji-178	310	21	encouraging	encourage	VERB
aji-178	310	22	immunological	immunological	ADJ
aji-178	310	23	attributes	attribute	NOUN
aji-178	310	24	capable	capable	ADJ
aji-178	310	25	of	of	ADP
aji-178	310	26	promoting	promote	VERB
aji-178	310	27	both	both	CCONJ
aji-178	310	28	humoral	humoral	ADJ
aji-178	310	29	and	and	CCONJ
aji-178	310	30	cellular	cellular	ADJ
aji-178	310	31	immunity	immunity	NOUN
aji-178	310	32	.	.	PUNCT
aji-178	311	1	building	build	VERB
aji-178	311	2	upon	upon	SCONJ
aji-178	311	3	these	these	DET
aji-178	311	4	findings	finding	NOUN
aji-178	311	5	,	,	PUNCT
aji-178	311	6	future	future	ADJ
aji-178	311	7	work	work	NOUN
aji-178	311	8	will	will	AUX
aji-178	311	9	focus	focus	VERB
aji-178	311	10	on	on	ADP
aji-178	311	11	validating	validate	VERB
aji-178	311	12	the	the	DET
aji-178	311	13	efficacy	efficacy	NOUN
aji-178	311	14	of	of	ADP
aji-178	311	15	the	the	DET
aji-178	311	16	proposed	propose	VERB
aji-178	311	17	vaccine	vaccine	NOUN
aji-178	311	18	as	as	ADP
aji-178	311	19	both	both	CCONJ
aji-178	311	20	a	a	DET
aji-178	311	21	preventive	preventive	ADJ
aji-178	311	22	and	and	CCONJ
aji-178	311	23	therapeutic	therapeutic	ADJ
aji-178	311	24	candidate	candidate	NOUN
aji-178	311	25	through	through	ADP
aji-178	311	26	in	in	ADP
aji-178	311	27	vivo	vivo	ADJ
aji-178	311	28	evaluation	evaluation	NOUN
aji-178	311	29	in	in	ADP
aji-178	311	30	a	a	DET
aji-178	311	31	suitable	suitable	ADJ
aji-178	311	32	mouse	mouse	NOUN
aji-178	311	33	model	model	NOUN
aji-178	311	34	.	.	PUNCT
aji-178	312	1	therefore	therefore	ADV
aji-178	312	2	,	,	PUNCT
aji-178	312	3	it	it	PRON
aji-178	312	4	should	should	AUX
aji-178	312	5	be	be	AUX
aji-178	312	6	pushed	push	VERB
aji-178	312	7	forward	forward	ADV
aji-178	312	8	as	as	ADP
aji-178	312	9	a	a	DET
aji-178	312	10	potential	potential	ADJ
aji-178	312	11	lead	lead	ADJ
aji-178	312	12	candidate	candidate	NOUN
aji-178	312	13	for	for	ADP
aji-178	312	14	in	in	ADP
aji-178	312	15	vivo	vivo	NOUN
aji-178	312	16	and	and	CCONJ
aji-178	312	17	in	in	ADP
aji-178	312	18	vitro	vitro	X
aji-178	312	19	assessments	assessment	NOUN
aji-178	312	20	against	against	ADP
aji-178	312	21	m.	m.	NOUN
aji-178	312	22	tb	tb	PROPN
aji-178	312	23	.	.	PUNCT
aji-178	313	1	(	(	PUNCT
aji-178	313	2	yun	yun	PROPN
aji-178	313	3	et	et	PROPN
aji-178	313	4	al	al	PROPN
aji-178	313	5	.	.	PROPN
aji-178	313	6	,	,	PUNCT
aji-178	313	7	2024	2024	NUM
aji-178	313	8	;	;	PUNCT
aji-178	313	9	nayak	nayak	PROPN
aji-178	313	10	et	et	PROPN
aji-178	313	11	al	al	PROPN
aji-178	313	12	.	.	PROPN
aji-178	313	13	,	,	PUNCT
aji-178	313	14	2023	2023	NUM
aji-178	313	15	)	)	PUNCT
aji-178	313	16	.	.	PUNCT
aji-178	314	1	disclaimer	disclaimer	NOUN
aji-178	314	2	(	(	PUNCT
aji-178	314	3	artificial	artificial	ADJ
aji-178	314	4	intelligence	intelligence	NOUN
aji-178	314	5	)	)	PUNCT
aji-178	314	6	author(s	author(s	NOUN
aji-178	314	7	)	)	PUNCT
aji-178	314	8	hereby	hereby	ADV
aji-178	314	9	declare	declare	VERB
aji-178	314	10	that	that	SCONJ
aji-178	314	11	no	no	DET
aji-178	314	12	generative	generative	NOUN
aji-178	314	13	ai	ai	VERB
aji-178	314	14	technologies	technology	NOUN
aji-178	314	15	such	such	ADJ
aji-178	314	16	as	as	ADP
aji-178	314	17	large	large	ADJ
aji-178	314	18	language	language	NOUN
aji-178	314	19	models	model	NOUN
aji-178	314	20	(	(	PUNCT
aji-178	314	21	chatgpt	chatgpt	NOUN
aji-178	314	22	,	,	PUNCT
aji-178	314	23	copilot	copilot	NOUN
aji-178	314	24	,	,	PUNCT
aji-178	314	25	etc	etc	X
aji-178	314	26	)	)	PUNCT
aji-178	314	27	and	and	CCONJ
aji-178	314	28	text	text	NOUN
aji-178	314	29	-	-	PUNCT
aji-178	314	30	to	to	ADP
aji-178	314	31	-	-	PUNCT
aji-178	314	32	image	image	NOUN
aji-178	314	33	generators	generator	NOUN
aji-178	314	34	have	have	AUX
aji-178	314	35	been	be	AUX
aji-178	314	36	used	use	VERB
aji-178	314	37	during	during	ADP
aji-178	314	38	writing	writing	NOUN
aji-178	314	39	or	or	CCONJ
aji-178	314	40	editing	editing	NOUN
aji-178	314	41	of	of	ADP
aji-178	314	42	this	this	DET
aji-178	314	43	manuscript	manuscript	NOUN
aji-178	314	44	.	.	PUNCT
aji-178	315	1	competing	compete	VERB
aji-178	315	2	interests	interest	NOUN
aji-178	315	3	authors	author	NOUN
aji-178	315	4	have	have	AUX
aji-178	315	5	declared	declare	VERB
aji-178	315	6	that	that	SCONJ
aji-178	315	7	no	no	DET
aji-178	315	8	competing	compete	VERB
aji-178	315	9	interests	interest	NOUN
aji-178	315	10	exist	exist	VERB
aji-178	315	11	.	.	PUNCT
aji-178	316	1	references	reference	NOUN
aji-178	316	2	bellini	bellini	PROPN
aji-178	316	3	,	,	PUNCT
aji-178	316	4	c.	c.	NOUN
aji-178	316	5	,	,	PUNCT
aji-178	316	6	&	&	CCONJ
aji-178	316	7	horváti	horváti	PROPN
aji-178	316	8	,	,	PUNCT
aji-178	316	9	k.	k.	PROPN
aji-178	316	10	(	(	PUNCT
aji-178	316	11	2020	2020	NUM
aji-178	316	12	)	)	PUNCT
aji-178	316	13	.	.	PUNCT
aji-178	317	1	recent	recent	ADJ
aji-178	317	2	advances	advance	NOUN
aji-178	317	3	in	in	ADP
aji-178	317	4	the	the	DET
aji-178	317	5	development	development	NOUN
aji-178	317	6	of	of	ADP
aji-178	317	7	proteinand	proteinand	NOUN
aji-178	317	8	peptide	peptide	NOUN
aji-178	317	9	naseema	naseema	NOUN
aji-178	317	10	;	;	PUNCT
aji-178	317	11	asian	asian	PROPN
aji-178	317	12	j.	j.	PROPN
aji-178	317	13	immunol	immunol	PROPN
aji-178	317	14	.	.	PROPN
aji-178	317	15	,	,	PUNCT
aji-178	317	16	vol	vol	NOUN
aji-178	317	17	.	.	PROPN
aji-178	317	18	8	8	NUM
aji-178	317	19	,	,	PUNCT
aji-178	317	20	no	no	INTJ
aji-178	317	21	.	.	NOUN
aji-178	317	22	1	1	NUM
aji-178	317	23	,	,	PUNCT
aji-178	317	24	pp	pp	ADJ
aji-178	317	25	.	.	PUNCT
aji-178	317	26	269	269	NUM
aji-178	317	27	-	-	SYM
aji-178	317	28	284	284	NUM
aji-178	317	29	,	,	PUNCT
aji-178	317	30	2025	2025	NUM
aji-178	317	31	;	;	PUNCT
aji-178	317	32	article	article	NOUN
aji-178	317	33	no.aji.147582	no.aji.147582	NOUN
aji-178	317	34	279	279	NUM
aji-178	317	35	based	base	VERB
aji-178	317	36	subunit	subunit	NOUN
aji-178	317	37	vaccines	vaccine	NOUN
aji-178	317	38	against	against	ADP
aji-178	317	39	tuberculosis	tuberculosis	NOUN
aji-178	317	40	.	.	PUNCT
aji-178	318	1	cells	cell	NOUN
aji-178	318	2	,	,	PUNCT
aji-178	318	3	9(12	9(12	NUM
aji-178	318	4	)	)	PUNCT
aji-178	318	5	,	,	PUNCT
aji-178	318	6	2673	2673	NUM
aji-178	318	7	.	.	PUNCT
aji-178	319	1	beresford	beresford	PROPN
aji-178	319	2	,	,	PUNCT
aji-178	319	3	b.	b.	PROPN
aji-178	319	4	,	,	PUNCT
aji-178	319	5	&	&	CCONJ
aji-178	319	6	sadoff	sadoff	PROPN
aji-178	319	7	,	,	PUNCT
aji-178	319	8	j.	j.	PROPN
aji-178	319	9	c.	c.	PROPN
aji-178	319	10	(	(	PUNCT
aji-178	319	11	2010	2010	NUM
aji-178	319	12	)	)	PUNCT
aji-178	319	13	.	.	PUNCT
aji-178	320	1	update	update	NOUN
aji-178	320	2	on	on	ADP
aji-178	320	3	research	research	NOUN
aji-178	320	4	and	and	CCONJ
aji-178	320	5	development	development	NOUN
aji-178	320	6	pipeline	pipeline	NOUN
aji-178	320	7	:	:	PUNCT
aji-178	320	8	tuberculosis	tuberculosis	NOUN
aji-178	320	9	vaccines	vaccine	NOUN
aji-178	320	10	.	.	PUNCT
aji-178	321	1	clinical	clinical	ADJ
aji-178	321	2	infectious	infectious	ADJ
aji-178	321	3	diseases	disease	NOUN
aji-178	321	4	,	,	PUNCT
aji-178	321	5	50(suppl	50(suppl	NUM
aji-178	321	6	.	.	NOUN
aji-178	321	7	3	3	NUM
aji-178	321	8	)	)	PUNCT
aji-178	321	9	,	,	PUNCT
aji-178	321	10	s178	s178	PROPN
aji-178	321	11	–	–	PUNCT
aji-178	321	12	s183	s183	PROPN
aji-178	321	13	.	.	PUNCT
aji-178	322	1	bigi	bigi	PROPN
aji-178	322	2	,	,	PUNCT
aji-178	322	3	f.	f.	PROPN
aji-178	322	4	,	,	PUNCT
aji-178	322	5	alito	alito	PROPN
aji-178	322	6	,	,	PUNCT
aji-178	322	7	a.	a.	NOUN
aji-178	322	8	,	,	PUNCT
aji-178	322	9	romano	romano	NOUN
aji-178	322	10	,	,	PUNCT
aji-178	322	11	m.	m.	NOUN
aji-178	322	12	i.	i.	PROPN
aji-178	322	13	,	,	PUNCT
aji-178	322	14	zumarraga	zumarraga	PROPN
aji-178	322	15	,	,	PUNCT
aji-178	322	16	m.	m.	NOUN
aji-178	322	17	,	,	PUNCT
aji-178	322	18	caimi	caimi	PROPN
aji-178	322	19	,	,	PUNCT
aji-178	322	20	k.	k.	PROPN
aji-178	322	21	,	,	PUNCT
aji-178	322	22	&	&	CCONJ
aji-178	322	23	cataldi	cataldi	PROPN
aji-178	322	24	,	,	PUNCT
aji-178	322	25	a.	a.	NOUN
aji-178	322	26	(	(	PUNCT
aji-178	322	27	2000	2000	NUM
aji-178	322	28	)	)	PUNCT
aji-178	322	29	.	.	PUNCT
aji-178	323	1	the	the	DET
aji-178	323	2	gene	gene	NOUN
aji-178	323	3	encoding	encode	VERB
aji-178	323	4	p27	p27	NOUN
aji-178	323	5	lipoprotein	lipoprotein	NOUN
aji-178	323	6	and	and	CCONJ
aji-178	323	7	a	a	DET
aji-178	323	8	putative	putative	ADJ
aji-178	323	9	antibiotic	antibiotic	ADJ
aji-178	323	10	-	-	PUNCT
aji-178	323	11	resistance	resistance	NOUN
aji-178	323	12	gene	gene	NOUN
aji-178	323	13	form	form	VERB
aji-178	323	14	an	an	DET
aji-178	323	15	operon	operon	NOUN
aji-178	323	16	in	in	ADP
aji-178	323	17	mycobacterium	mycobacterium	NOUN
aji-178	323	18	tuberculosis	tuberculosis	NOUN
aji-178	323	19	and	and	CCONJ
aji-178	323	20	mycobacterium	mycobacterium	NOUN
aji-178	323	21	bovis	bovis	NOUN
aji-178	323	22	.	.	PUNCT
aji-178	324	1	microbiology	microbiology	NOUN
aji-178	324	2	,	,	PUNCT
aji-178	324	3	146(4	146(4	NUM
aji-178	324	4	)	)	PUNCT
aji-178	324	5	,	,	PUNCT
aji-178	324	6	1011–1018	1011–1018	NUM
aji-178	324	7	.	.	PUNCT
aji-178	325	1	binkowski	binkowski	PROPN
aji-178	325	2	,	,	PUNCT
aji-178	325	3	t.	t.	NOUN
aji-178	325	4	a.	a.	NOUN
aji-178	325	5	,	,	PUNCT
aji-178	325	6	naghibzadeh	naghibzadeh	NOUN
aji-178	325	7	,	,	PUNCT
aji-178	325	8	s.	s.	PROPN
aji-178	325	9	,	,	PUNCT
aji-178	325	10	&	&	CCONJ
aji-178	325	11	liang	liang	PROPN
aji-178	325	12	,	,	PUNCT
aji-178	325	13	j.	j.	PROPN
aji-178	325	14	(	(	PUNCT
aji-178	325	15	2003	2003	NUM
aji-178	325	16	)	)	PUNCT
aji-178	325	17	.	.	PUNCT
aji-178	326	1	castp	castp	PROPN
aji-178	326	2	:	:	PUNCT
aji-178	326	3	computed	compute	VERB
aji-178	326	4	atlas	atlas	PROPN
aji-178	326	5	of	of	ADP
aji-178	326	6	surface	surface	NOUN
aji-178	326	7	topography	topography	NOUN
aji-178	326	8	of	of	ADP
aji-178	326	9	proteins	protein	NOUN
aji-178	326	10	.	.	PUNCT
aji-178	327	1	nucleic	nucleic	ADJ
aji-178	327	2	acids	acid	NOUN
aji-178	327	3	research	research	NOUN
aji-178	327	4	,	,	PUNCT
aji-178	327	5	31(13	31(13	NUM
aji-178	327	6	)	)	PUNCT
aji-178	327	7	,	,	PUNCT
aji-178	327	8	3352–3355	3352–3355	NUM
aji-178	327	9	.	.	PUNCT
aji-178	328	1	brandt	brandt	PROPN
aji-178	328	2	,	,	PUNCT
aji-178	328	3	l.	l.	PROPN
aji-178	328	4	,	,	PUNCT
aji-178	328	5	cunha	cunha	PROPN
aji-178	328	6	,	,	PUNCT
aji-178	328	7	j.	j.	PROPN
aji-178	328	8	f.	f.	PROPN
aji-178	328	9	,	,	PUNCT
aji-178	328	10	olsen	olsen	PROPN
aji-178	328	11	,	,	PUNCT
aji-178	328	12	a.	a.	PROPN
aji-178	328	13	w.	w.	PROPN
aji-178	328	14	,	,	PUNCT
aji-178	328	15	chilima	chilima	PROPN
aji-178	328	16	,	,	PUNCT
aji-178	328	17	b.	b.	PROPN
aji-178	328	18	,	,	PUNCT
aji-178	328	19	hirsch	hirsch	PROPN
aji-178	328	20	,	,	PUNCT
aji-178	328	21	p.	p.	PROPN
aji-178	328	22	,	,	PUNCT
aji-178	328	23	appelberg	appelberg	PROPN
aji-178	328	24	,	,	PUNCT
aji-178	328	25	r.	r.	PROPN
aji-178	328	26	,	,	PUNCT
aji-178	328	27	&	&	CCONJ
aji-178	328	28	andersen	andersen	PROPN
aji-178	328	29	,	,	PUNCT
aji-178	328	30	p.	p.	PROPN
aji-178	328	31	(	(	PUNCT
aji-178	328	32	2002	2002	NUM
aji-178	328	33	)	)	PUNCT
aji-178	328	34	.	.	PUNCT
aji-178	329	1	failure	failure	NOUN
aji-178	329	2	of	of	ADP
aji-178	329	3	the	the	DET
aji-178	329	4	mycobacterium	mycobacterium	NOUN
aji-178	329	5	bovis	bovi	VERB
aji-178	329	6	bcg	bcg	PROPN
aji-178	329	7	vaccine	vaccine	NOUN
aji-178	329	8	:	:	PUNCT
aji-178	329	9	some	some	DET
aji-178	329	10	species	specie	NOUN
aji-178	329	11	of	of	ADP
aji-178	329	12	environmental	environmental	ADJ
aji-178	329	13	mycobacteria	mycobacteria	NOUN
aji-178	329	14	block	block	NOUN
aji-178	329	15	multiplication	multiplication	NOUN
aji-178	329	16	of	of	ADP
aji-178	329	17	bcg	bcg	NOUN
aji-178	329	18	and	and	CCONJ
aji-178	329	19	induction	induction	NOUN
aji-178	329	20	of	of	ADP
aji-178	329	21	protective	protective	ADJ
aji-178	329	22	immunity	immunity	NOUN
aji-178	329	23	to	to	PART
aji-178	329	24	tuberculosis	tuberculosis	VERB
aji-178	329	25	.	.	PUNCT
aji-178	330	1	infection	infection	NOUN
aji-178	330	2	and	and	CCONJ
aji-178	330	3	immunity	immunity	NOUN
aji-178	330	4	,	,	PUNCT
aji-178	330	5	70(2	70(2	NUM
aji-178	330	6	)	)	PUNCT
aji-178	330	7	,	,	PUNCT
aji-178	330	8	672–678	672–678	NUM
aji-178	330	9	.	.	PUNCT
aji-178	331	1	branger	branger	PROPN
aji-178	331	2	,	,	PUNCT
aji-178	331	3	j.	j.	PROPN
aji-178	331	4	,	,	PUNCT
aji-178	331	5	leemans	leemans	PROPN
aji-178	331	6	,	,	PUNCT
aji-178	331	7	j.	j.	PROPN
aji-178	331	8	c.	c.	PROPN
aji-178	331	9	,	,	PUNCT
aji-178	331	10	florquin	florquin	NOUN
aji-178	331	11	,	,	PUNCT
aji-178	331	12	s.	s.	PROPN
aji-178	331	13	,	,	PUNCT
aji-178	331	14	weijer	weijer	PROPN
aji-178	331	15	,	,	PUNCT
aji-178	331	16	s.	s.	PROPN
aji-178	331	17	,	,	PUNCT
aji-178	331	18	speelman	speelman	NOUN
aji-178	331	19	,	,	PUNCT
aji-178	331	20	p.	p.	NOUN
aji-178	331	21	,	,	PUNCT
aji-178	331	22	&	&	CCONJ
aji-178	331	23	van	van	PROPN
aji-178	331	24	der	der	PROPN
aji-178	331	25	poll	poll	NOUN
aji-178	331	26	,	,	PUNCT
aji-178	331	27	t.	t.	PROPN
aji-178	331	28	(	(	PUNCT
aji-178	331	29	2004	2004	NUM
aji-178	331	30	)	)	PUNCT
aji-178	331	31	.	.	PUNCT
aji-178	332	1	toll‑like	toll‑like	VERB
aji-178	332	2	receptor	receptor	NOUN
aji-178	332	3	4	4	NUM
aji-178	332	4	plays	play	VERB
aji-178	332	5	a	a	DET
aji-178	332	6	protective	protective	ADJ
aji-178	332	7	role	role	NOUN
aji-178	332	8	in	in	ADP
aji-178	332	9	pulmonary	pulmonary	ADJ
aji-178	332	10	tuberculosis	tuberculosis	NOUN
aji-178	332	11	in	in	ADP
aji-178	332	12	mice	mouse	NOUN
aji-178	332	13	.	.	PUNCT
aji-178	333	1	international	international	ADJ
aji-178	333	2	immunology	immunology	NOUN
aji-178	333	3	,	,	PUNCT
aji-178	333	4	16(3	16(3	NOUN
aji-178	333	5	)	)	PUNCT
aji-178	333	6	,	,	PUNCT
aji-178	333	7	509–516	509–516	NUM
aji-178	333	8	.	.	PUNCT
aji-178	334	1	brosch	brosch	PROPN
aji-178	334	2	,	,	PUNCT
aji-178	334	3	r.	r.	PROPN
aji-178	334	4	,	,	PUNCT
aji-178	334	5	et	et	PROPN
aji-178	334	6	al	al	PROPN
aji-178	334	7	.	.	PUNCT
aji-178	334	8	(	(	PUNCT
aji-178	334	9	2007	2007	NUM
aji-178	334	10	)	)	PUNCT
aji-178	334	11	.	.	PUNCT
aji-178	335	1	genome	genome	NOUN
aji-178	335	2	plasticity	plasticity	NOUN
aji-178	335	3	of	of	ADP
aji-178	335	4	bcg	bcg	NOUN
aji-178	335	5	and	and	CCONJ
aji-178	335	6	impact	impact	NOUN
aji-178	335	7	on	on	ADP
aji-178	335	8	vaccine	vaccine	NOUN
aji-178	335	9	efficacy	efficacy	NOUN
aji-178	335	10	.	.	PUNCT
aji-178	336	1	proceedings	proceeding	NOUN
aji-178	336	2	of	of	ADP
aji-178	336	3	the	the	DET
aji-178	336	4	national	national	PROPN
aji-178	336	5	academy	academy	PROPN
aji-178	336	6	of	of	ADP
aji-178	336	7	sciences	sciences	PROPN
aji-178	336	8	,	,	PUNCT
aji-178	336	9	104	104	NUM
aji-178	336	10	,	,	PUNCT
aji-178	336	11	5596–5601	5596–5601	NUM
aji-178	336	12	.	.	X
aji-178	336	13	carmona	carmona	PROPN
aji-178	336	14	,	,	PUNCT
aji-178	336	15	j.	j.	PROPN
aji-178	336	16	,	,	PUNCT
aji-178	336	17	cruz	cruz	PROPN
aji-178	336	18	,	,	PUNCT
aji-178	336	19	a.	a.	PROPN
aji-178	336	20	,	,	PUNCT
aji-178	336	21	moreira	moreira	PROPN
aji-178	336	22	-	-	PUNCT
aji-178	336	23	teixeira	teixeira	PROPN
aji-178	336	24	,	,	PUNCT
aji-178	336	25	l.	l.	PROPN
aji-178	336	26	,	,	PUNCT
aji-178	336	27	sousa	sousa	PROPN
aji-178	336	28	,	,	PUNCT
aji-178	336	29	c.	c.	PROPN
aji-178	336	30	,	,	PUNCT
aji-178	336	31	sousa	sousa	PROPN
aji-178	336	32	,	,	PUNCT
aji-178	336	33	j.	j.	PROPN
aji-178	336	34	,	,	PUNCT
aji-178	336	35	osorio	osorio	PROPN
aji-178	336	36	,	,	PUNCT
aji-178	336	37	n.	n.	PROPN
aji-178	336	38	s.	s.	PROPN
aji-178	336	39	,	,	PUNCT
aji-178	336	40	saraiva	saraiva	PROPN
aji-178	336	41	,	,	PUNCT
aji-178	336	42	a.	a.	PROPN
aji-178	336	43	l.	l.	PROPN
aji-178	336	44	,	,	PUNCT
aji-178	336	45	et	et	PROPN
aji-178	336	46	al	al	PROPN
aji-178	336	47	.	.	PROPN
aji-178	336	48	(	(	PUNCT
aji-178	336	49	2013	2013	NUM
aji-178	336	50	)	)	PUNCT
aji-178	336	51	.	.	PUNCT
aji-178	337	1	mycobacterium	mycobacterium	NOUN
aji-178	337	2	tuberculosis	tuberculosis	NOUN
aji-178	337	3	strains	strain	NOUN
aji-178	337	4	are	be	AUX
aji-178	337	5	differentially	differentially	ADV
aji-178	337	6	recognized	recognize	VERB
aji-178	337	7	by	by	ADP
aji-178	337	8	tlrs	tlrs	NOUN
aji-178	337	9	with	with	ADP
aji-178	337	10	an	an	DET
aji-178	337	11	impact	impact	NOUN
aji-178	337	12	on	on	ADP
aji-178	337	13	the	the	DET
aji-178	337	14	immune	immune	ADJ
aji-178	337	15	response	response	NOUN
aji-178	337	16	.	.	PUNCT
aji-178	338	1	plos	plos	PROPN
aji-178	338	2	one	one	NUM
aji-178	338	3	,	,	PUNCT
aji-178	338	4	8(6	8(6	NUM
aji-178	338	5	)	)	PUNCT
aji-178	338	6	,	,	PUNCT
aji-178	338	7	e67277	e67277	NOUN
aji-178	338	8	.	.	PUNCT
aji-178	339	1	choi	choi	PROPN
aji-178	339	2	,	,	PUNCT
aji-178	339	3	h.-g	h.-g	PROPN
aji-178	339	4	.	.	PROPN
aji-178	339	5	,	,	PUNCT
aji-178	339	6	kim	kim	PROPN
aji-178	339	7	,	,	PUNCT
aji-178	339	8	w.	w.	PROPN
aji-178	339	9	s.	s.	PROPN
aji-178	339	10	,	,	PUNCT
aji-178	339	11	back	back	ADV
aji-178	339	12	,	,	PUNCT
aji-178	339	13	y.	y.	PROPN
aji-178	339	14	w.	w.	PROPN
aji-178	339	15	,	,	PUNCT
aji-178	339	16	kim	kim	PROPN
aji-178	339	17	,	,	PUNCT
aji-178	339	18	h.	h.	PROPN
aji-178	339	19	,	,	PUNCT
aji-178	339	20	kwon	kwon	PROPN
aji-178	339	21	,	,	PUNCT
aji-178	339	22	k.	k.	PROPN
aji-178	339	23	w.	w.	PROPN
aji-178	339	24	,	,	PUNCT
aji-178	339	25	kim	kim	PROPN
aji-178	339	26	,	,	PUNCT
aji-178	339	27	j.-s	j.-s	PROPN
aji-178	339	28	.	.	PUNCT
aji-178	339	29	,	,	PUNCT
aji-178	339	30	shin	shin	PROPN
aji-178	339	31	,	,	PUNCT
aji-178	339	32	s.	s.	PROPN
aji-178	339	33	j.	j.	PROPN
aji-178	339	34	,	,	PUNCT
aji-178	339	35	&	&	CCONJ
aji-178	339	36	kim	kim	PROPN
aji-178	339	37	,	,	PUNCT
aji-178	339	38	h.-j	h.-j	PROPN
aji-178	339	39	.	.	PUNCT
aji-178	340	1	(	(	PUNCT
aji-178	340	2	2015	2015	NUM
aji-178	340	3	)	)	PUNCT
aji-178	340	4	.	.	PUNCT
aji-178	341	1	mycobacterium	mycobacterium	NOUN
aji-178	341	2	tuberculosis	tuberculosis	NOUN
aji-178	341	3	rpfe	rpfe	AUX
aji-178	341	4	promotes	promote	VERB
aji-178	341	5	simultaneous	simultaneous	ADJ
aji-178	341	6	th1and	th1and	NOUN
aji-178	341	7	th17	th17	NOUN
aji-178	341	8	-	-	PUNCT
aji-178	341	9	type	type	NOUN
aji-178	341	10	t	t	NOUN
aji-178	341	11	-	-	PUNCT
aji-178	341	12	cell	cell	NOUN
aji-178	341	13	immunity	immunity	NOUN
aji-178	341	14	via	via	ADP
aji-178	341	15	tlr4dependent	tlr4dependent	DET
aji-178	341	16	maturation	maturation	NOUN
aji-178	341	17	of	of	ADP
aji-178	341	18	dendritic	dendritic	ADJ
aji-178	341	19	cells	cell	NOUN
aji-178	341	20	.	.	PUNCT
aji-178	342	1	european	european	ADJ
aji-178	342	2	journal	journal	PROPN
aji-178	342	3	of	of	ADP
aji-178	342	4	immunology	immunology	NOUN
aji-178	342	5	,	,	PUNCT
aji-178	342	6	45(7	45(7	NUM
aji-178	342	7	)	)	PUNCT
aji-178	342	8	,	,	PUNCT
aji-178	342	9	1957–1971	1957–1971	NUM
aji-178	342	10	.	.	PUNCT
aji-178	343	1	dimitrov	dimitrov	PROPN
aji-178	343	2	,	,	PUNCT
aji-178	343	3	i.	i.	NOUN
aji-178	343	4	,	,	PUNCT
aji-178	343	5	bangov	bangov	NOUN
aji-178	343	6	,	,	PUNCT
aji-178	343	7	i.	i.	PROPN
aji-178	343	8	,	,	PUNCT
aji-178	343	9	flower	flower	PROPN
aji-178	343	10	,	,	PUNCT
aji-178	343	11	d.	d.	PROPN
aji-178	343	12	r.	r.	PROPN
aji-178	343	13	,	,	PUNCT
aji-178	343	14	&	&	CCONJ
aji-178	343	15	doytchinova	doytchinova	PROPN
aji-178	343	16	,	,	PUNCT
aji-178	343	17	i.	i.	PROPN
aji-178	343	18	(	(	PUNCT
aji-178	343	19	2014	2014	NUM
aji-178	343	20	)	)	PUNCT
aji-178	343	21	.	.	PUNCT
aji-178	344	1	allertop	allertop	VERB
aji-178	344	2	v.	v.	ADP
aji-178	344	3	2	2	NUM
aji-178	344	4	—	—	PUNCT
aji-178	344	5	a	a	DET
aji-178	344	6	server	server	NOUN
aji-178	344	7	for	for	ADP
aji-178	344	8	in	in	ADP
aji-178	344	9	silico	silico	NOUN
aji-178	344	10	prediction	prediction	NOUN
aji-178	344	11	of	of	ADP
aji-178	344	12	allergens	allergen	NOUN
aji-178	344	13	.	.	PUNCT
aji-178	345	1	journal	journal	NOUN
aji-178	345	2	of	of	ADP
aji-178	345	3	molecular	molecular	ADJ
aji-178	345	4	modeling	modeling	NOUN
aji-178	345	5	,	,	PUNCT
aji-178	345	6	20(6	20(6	NOUN
aji-178	345	7	)	)	PUNCT
aji-178	345	8	,	,	PUNCT
aji-178	345	9	1–6	1–6	X
aji-178	345	10	.	.	PUNCT
aji-178	345	11	doytchinova	doytchinova	PROPN
aji-178	345	12	,	,	PUNCT
aji-178	345	13	i.	i.	PROPN
aji-178	345	14	a.	a.	PROPN
aji-178	345	15	,	,	PUNCT
aji-178	345	16	&	&	CCONJ
aji-178	345	17	flower	flower	PROPN
aji-178	345	18	,	,	PUNCT
aji-178	345	19	d.	d.	PROPN
aji-178	345	20	r.	r.	PROPN
aji-178	345	21	(	(	PUNCT
aji-178	345	22	2007	2007	NUM
aji-178	345	23	)	)	PUNCT
aji-178	345	24	.	.	PUNCT
aji-178	346	1	vaxijen	vaxijen	NOUN
aji-178	346	2	:	:	PUNCT
aji-178	346	3	a	a	DET
aji-178	346	4	server	server	NOUN
aji-178	346	5	for	for	ADP
aji-178	346	6	prediction	prediction	NOUN
aji-178	346	7	of	of	ADP
aji-178	346	8	protective	protective	ADJ
aji-178	346	9	antigens	antigen	NOUN
aji-178	346	10	,	,	PUNCT
aji-178	346	11	tumour	tumour	NOUN
aji-178	346	12	antigens	antigen	NOUN
aji-178	346	13	and	and	CCONJ
aji-178	346	14	subunit	subunit	NOUN
aji-178	346	15	vaccines	vaccine	NOUN
aji-178	346	16	.	.	PUNCT
aji-178	347	1	bmc	bmc	ADJ
aji-178	347	2	bioinformatics	bioinformatics	PROPN
aji-178	347	3	,	,	PUNCT
aji-178	347	4	8(1	8(1	NOUN
aji-178	347	5	)	)	PUNCT
aji-178	347	6	,	,	PUNCT
aji-178	347	7	1–7	1–7	X
aji-178	347	8	.	.	PUNCT
aji-178	347	9	faust	faust	PROPN
aji-178	347	10	,	,	PUNCT
aji-178	347	11	l.	l.	PROPN
aji-178	347	12	,	,	PUNCT
aji-178	347	13	schreiber	schreiber	PROPN
aji-178	347	14	,	,	PUNCT
aji-178	347	15	y.	y.	PROPN
aji-178	347	16	,	,	PUNCT
aji-178	347	17	&	&	CCONJ
aji-178	347	18	bocking	bocke	VERB
aji-178	347	19	,	,	PUNCT
aji-178	347	20	n.	n.	NOUN
aji-178	347	21	(	(	PUNCT
aji-178	347	22	2019	2019	NUM
aji-178	347	23	)	)	PUNCT
aji-178	347	24	.	.	PUNCT
aji-178	348	1	a	a	DET
aji-178	348	2	systematic	systematic	ADJ
aji-178	348	3	review	review	NOUN
aji-178	348	4	of	of	ADP
aji-178	348	5	bcg	bcg	NOUN
aji-178	348	6	vaccination	vaccination	NOUN
aji-178	348	7	policies	policy	NOUN
aji-178	348	8	among	among	ADP
aji-178	348	9	high	high	ADJ
aji-178	348	10	-	-	PUNCT
aji-178	348	11	risk	risk	NOUN
aji-178	348	12	groups	group	NOUN
aji-178	348	13	in	in	ADP
aji-178	348	14	low	low	ADJ
aji-178	348	15	tbburden	tbburden	ADJ
aji-178	348	16	countries	country	NOUN
aji-178	348	17	:	:	PUNCT
aji-178	348	18	implications	implication	NOUN
aji-178	348	19	for	for	ADP
aji-178	348	20	vaccination	vaccination	NOUN
aji-178	348	21	strategy	strategy	NOUN
aji-178	348	22	in	in	ADP
aji-178	348	23	canadian	canadian	ADJ
aji-178	348	24	indigenous	indigenous	ADJ
aji-178	348	25	communities	community	NOUN
aji-178	348	26	.	.	PUNCT
aji-178	349	1	bmc	bmc	ADJ
aji-178	349	2	public	public	ADJ
aji-178	349	3	health	health	NOUN
aji-178	349	4	,	,	PUNCT
aji-178	349	5	19(1	19(1	NUM
aji-178	349	6	)	)	PUNCT
aji-178	349	7	,	,	PUNCT
aji-178	349	8	1–32	1–32	PROPN
aji-178	349	9	.	.	PUNCT
aji-178	350	1	ferraz	ferraz	PROPN
aji-178	350	2	,	,	PUNCT
aji-178	350	3	j.	j.	PROPN
aji-178	350	4	c.	c.	PROPN
aji-178	350	5	,	,	PUNCT
aji-178	350	6	stavropoulos	stavropoulos	PROPN
aji-178	350	7	,	,	PUNCT
aji-178	350	8	e.	e.	PROPN
aji-178	350	9	,	,	PUNCT
aji-178	350	10	yang	yang	PROPN
aji-178	350	11	,	,	PUNCT
aji-178	350	12	m.	m.	NOUN
aji-178	350	13	,	,	PUNCT
aji-178	350	14	coade	coade	PROPN
aji-178	350	15	,	,	PUNCT
aji-178	350	16	s.	s.	PROPN
aji-178	350	17	,	,	PUNCT
aji-178	350	18	espitia	espitia	PROPN
aji-178	350	19	,	,	PUNCT
aji-178	350	20	c.	c.	PROPN
aji-178	350	21	,	,	PUNCT
aji-178	350	22	lowrie	lowrie	PROPN
aji-178	350	23	,	,	PUNCT
aji-178	350	24	d.	d.	PROPN
aji-178	350	25	b.	b.	PROPN
aji-178	350	26	,	,	PUNCT
aji-178	350	27	colston	colston	PROPN
aji-178	350	28	,	,	PUNCT
aji-178	350	29	m.	m.	PROPN
aji-178	350	30	j.	j.	PROPN
aji-178	350	31	,	,	PUNCT
aji-178	350	32	&	&	CCONJ
aji-178	350	33	tascon	tascon	PROPN
aji-178	350	34	,	,	PUNCT
aji-178	350	35	r.	r.	PROPN
aji-178	350	36	e.	e.	PROPN
aji-178	350	37	(	(	PUNCT
aji-178	350	38	2004	2004	NUM
aji-178	350	39	)	)	PUNCT
aji-178	350	40	.	.	PUNCT
aji-178	351	1	a	a	DET
aji-178	351	2	heterologous	heterologous	ADJ
aji-178	351	3	dna	dna	NOUN
aji-178	351	4	priming	priming	NOUN
aji-178	351	5	-	-	PUNCT
aji-178	351	6	mycobacterium	mycobacterium	NOUN
aji-178	351	7	bovis	bovi	VERB
aji-178	351	8	bcg	bcg	NOUN
aji-178	351	9	boosting	boost	VERB
aji-178	351	10	immunization	immunization	NOUN
aji-178	351	11	strategy	strategy	NOUN
aji-178	351	12	using	use	VERB
aji-178	351	13	mycobacterial	mycobacterial	ADJ
aji-178	351	14	hsp70	hsp70	NOUN
aji-178	351	15	,	,	PUNCT
aji-178	351	16	hsp65	hsp65	NOUN
aji-178	351	17	,	,	PUNCT
aji-178	351	18	and	and	CCONJ
aji-178	351	19	apa	apa	PROPN
aji-178	351	20	antigens	antigen	NOUN
aji-178	351	21	improves	improve	VERB
aji-178	351	22	protection	protection	NOUN
aji-178	351	23	against	against	ADP
aji-178	351	24	tuberculosis	tuberculosis	NOUN
aji-178	351	25	in	in	ADP
aji-178	351	26	mice	mouse	NOUN
aji-178	351	27	.	.	PUNCT
aji-178	352	1	infection	infection	NOUN
aji-178	352	2	and	and	CCONJ
aji-178	352	3	immunity	immunity	NOUN
aji-178	352	4	,	,	PUNCT
aji-178	352	5	72(12	72(12	NUM
aji-178	352	6	)	)	PUNCT
aji-178	352	7	,	,	PUNCT
aji-178	352	8	6945–6950	6945–6950	NUM
aji-178	352	9	.	.	PUNCT
aji-178	353	1	fleri	fleri	PROPN
aji-178	353	2	,	,	PUNCT
aji-178	353	3	w.	w.	PROPN
aji-178	353	4	,	,	PUNCT
aji-178	353	5	paul	paul	PROPN
aji-178	353	6	,	,	PUNCT
aji-178	353	7	s.	s.	PROPN
aji-178	353	8	,	,	PUNCT
aji-178	353	9	dhanda	dhanda	PROPN
aji-178	353	10	,	,	PUNCT
aji-178	353	11	s.	s.	PROPN
aji-178	353	12	k.	k.	PROPN
aji-178	353	13	,	,	PUNCT
aji-178	353	14	mahajan	mahajan	PROPN
aji-178	353	15	,	,	PUNCT
aji-178	353	16	s.	s.	PROPN
aji-178	353	17	,	,	PUNCT
aji-178	353	18	xu	xu	PROPN
aji-178	353	19	,	,	PUNCT
aji-178	353	20	x.	x.	PROPN
aji-178	353	21	,	,	PUNCT
aji-178	353	22	peters	peters	PROPN
aji-178	353	23	,	,	PUNCT
aji-178	353	24	b.	b.	PROPN
aji-178	353	25	,	,	PUNCT
aji-178	353	26	&	&	CCONJ
aji-178	353	27	sette	sette	PROPN
aji-178	353	28	,	,	PUNCT
aji-178	353	29	a.	a.	NOUN
aji-178	353	30	(	(	PUNCT
aji-178	353	31	2017	2017	NUM
aji-178	353	32	)	)	PUNCT
aji-178	353	33	.	.	PUNCT
aji-178	354	1	the	the	DET
aji-178	354	2	immune	immune	ADJ
aji-178	354	3	epitope	epitope	NOUN
aji-178	354	4	database	database	NOUN
aji-178	354	5	and	and	CCONJ
aji-178	354	6	analysis	analysis	NOUN
aji-178	354	7	resource	resource	NOUN
aji-178	354	8	in	in	ADP
aji-178	354	9	epitope	epitope	NOUN
aji-178	354	10	discovery	discovery	NOUN
aji-178	354	11	and	and	CCONJ
aji-178	354	12	synthetic	synthetic	ADJ
aji-178	354	13	vaccine	vaccine	NOUN
aji-178	354	14	design	design	NOUN
aji-178	354	15	.	.	PUNCT
aji-178	355	1	frontiers	frontier	NOUN
aji-178	355	2	in	in	ADP
aji-178	355	3	immunology	immunology	NOUN
aji-178	355	4	,	,	PUNCT
aji-178	355	5	8	8	NUM
aji-178	355	6	,	,	PUNCT
aji-178	355	7	278	278	NUM
aji-178	355	8	.	.	PUNCT
aji-178	355	9	gülbay	gülbay	PROPN
aji-178	355	10	,	,	PUNCT
aji-178	355	11	b.	b.	PROPN
aji-178	355	12	e.	e.	PROPN
aji-178	355	13	,	,	PUNCT
aji-178	355	14	gürkan	gürkan	PROPN
aji-178	355	15	,	,	PUNCT
aji-178	355	16	ö.	ö.	PROPN
aji-178	355	17	u.	u.	PROPN
aji-178	355	18	,	,	PUNCT
aji-178	355	19	yıldız	yıldız	PROPN
aji-178	355	20	,	,	PUNCT
aji-178	355	21	ö.	ö.	PROPN
aji-178	355	22	a.	a.	PROPN
aji-178	355	23	,	,	PUNCT
aji-178	355	24	önen	önen	PROPN
aji-178	355	25	,	,	PUNCT
aji-178	355	26	z.	z.	PROPN
aji-178	355	27	p.	p.	PROPN
aji-178	355	28	,	,	PUNCT
aji-178	355	29	erkekol	erkekol	PROPN
aji-178	355	30	,	,	PUNCT
aji-178	355	31	f.	f.	PROPN
aji-178	355	32	ö.	ö.	PROPN
aji-178	355	33	,	,	PUNCT
aji-178	355	34	baççıoğlu	baççıoğlu	NOUN
aji-178	355	35	,	,	PUNCT
aji-178	355	36	a.	a.	NOUN
aji-178	355	37	,	,	PUNCT
aji-178	355	38	&	&	CCONJ
aji-178	355	39	acıcan	acıcan	PROPN
aji-178	355	40	,	,	PUNCT
aji-178	355	41	t.	t.	PROPN
aji-178	355	42	(	(	PUNCT
aji-178	355	43	2006	2006	NUM
aji-178	355	44	)	)	PUNCT
aji-178	355	45	.	.	PUNCT
aji-178	356	1	side	side	NOUN
aji-178	356	2	effects	effect	NOUN
aji-178	356	3	due	due	ADJ
aji-178	356	4	to	to	ADP
aji-178	356	5	primary	primary	ADJ
aji-178	356	6	antituberculosis	antituberculosis	NOUN
aji-178	356	7	drugs	drug	NOUN
aji-178	356	8	during	during	ADP
aji-178	356	9	the	the	DET
aji-178	356	10	initial	initial	ADJ
aji-178	356	11	phase	phase	NOUN
aji-178	356	12	of	of	ADP
aji-178	356	13	therapy	therapy	NOUN
aji-178	356	14	in	in	ADP
aji-178	356	15	1149	1149	NUM
aji-178	356	16	hospitalized	hospitalize	VERB
aji-178	356	17	patients	patient	NOUN
aji-178	356	18	for	for	ADP
aji-178	356	19	tuberculosis	tuberculosis	NOUN
aji-178	356	20	.	.	PUNCT
aji-178	357	1	respiratory	respiratory	ADJ
aji-178	357	2	medicine	medicine	NOUN
aji-178	357	3	,	,	PUNCT
aji-178	357	4	100(10	100(10	NUM
aji-178	357	5	)	)	PUNCT
aji-178	357	6	,	,	PUNCT
aji-178	357	7	1834–1842	1834–1842	NUM
aji-178	357	8	.	.	PUNCT
aji-178	358	1	gupta	gupta	PROPN
aji-178	358	2	,	,	PUNCT
aji-178	358	3	s.	s.	PROPN
aji-178	358	4	,	,	PUNCT
aji-178	358	5	kapoor	kapoor	PROPN
aji-178	358	6	,	,	PUNCT
aji-178	358	7	p.	p.	PROPN
aji-178	358	8	,	,	PUNCT
aji-178	358	9	chaudhary	chaudhary	PROPN
aji-178	358	10	,	,	PUNCT
aji-178	358	11	k.	k.	PROPN
aji-178	358	12	,	,	PUNCT
aji-178	358	13	gautam	gautam	PROPN
aji-178	358	14	,	,	PUNCT
aji-178	358	15	a.	a.	PROPN
aji-178	358	16	,	,	PUNCT
aji-178	358	17	kumar	kumar	PROPN
aji-178	358	18	,	,	PUNCT
aji-178	358	19	r.	r.	PROPN
aji-178	358	20	,	,	PUNCT
aji-178	358	21	open	open	ADJ
aji-178	358	22	source	source	NOUN
aji-178	358	23	drug	drug	NOUN
aji-178	358	24	discovery	discovery	PROPN
aji-178	358	25	consortium	consortium	PROPN
aji-178	358	26	,	,	PUNCT
aji-178	358	27	&	&	CCONJ
aji-178	358	28	raghava	raghava	PROPN
aji-178	358	29	,	,	PUNCT
aji-178	358	30	g.	g.	PROPN
aji-178	358	31	p.	p.	PROPN
aji-178	358	32	s.	s.	PROPN
aji-178	358	33	(	(	PUNCT
aji-178	358	34	2013	2013	NUM
aji-178	358	35	)	)	PUNCT
aji-178	358	36	.	.	PUNCT
aji-178	359	1	in	in	ADP
aji-178	359	2	silico	silico	NOUN
aji-178	359	3	approach	approach	NOUN
aji-178	359	4	for	for	ADP
aji-178	359	5	predicting	predict	VERB
aji-178	359	6	toxicity	toxicity	NOUN
aji-178	359	7	of	of	ADP
aji-178	359	8	peptides	peptide	NOUN
aji-178	359	9	and	and	CCONJ
aji-178	359	10	proteins	protein	NOUN
aji-178	359	11	.	.	PUNCT
aji-178	360	1	plos	plos	PROPN
aji-178	360	2	one	one	NUM
aji-178	360	3	,	,	PUNCT
aji-178	360	4	8(9	8(9	NUM
aji-178	360	5	)	)	PUNCT
aji-178	360	6	,	,	PUNCT
aji-178	360	7	e73957	e73957	NOUN
aji-178	360	8	.	.	PUNCT
aji-178	361	1	hart	hart	PROPN
aji-178	361	2	,	,	PUNCT
aji-178	361	3	p.	p.	PROPN
aji-178	361	4	d.	d.	PROPN
aji-178	361	5	,	,	PUNCT
aji-178	361	6	young	young	ADJ
aji-178	361	7	,	,	PUNCT
aji-178	361	8	m.	m.	PROPN
aji-178	361	9	r.	r.	PROPN
aji-178	361	10	,	,	PUNCT
aji-178	361	11	gordon	gordon	PROPN
aji-178	361	12	,	,	PUNCT
aji-178	361	13	a.	a.	PROPN
aji-178	361	14	h.	h.	PROPN
aji-178	361	15	,	,	PUNCT
aji-178	361	16	&	&	CCONJ
aji-178	361	17	sullivan	sullivan	PROPN
aji-178	361	18	,	,	PUNCT
aji-178	361	19	k.	k.	PROPN
aji-178	361	20	h.	h.	PROPN
aji-178	361	21	(	(	PUNCT
aji-178	361	22	1987	1987	NUM
aji-178	361	23	)	)	PUNCT
aji-178	361	24	.	.	PUNCT
aji-178	362	1	inhibition	inhibition	NOUN
aji-178	362	2	of	of	ADP
aji-178	362	3	phagosome	phagosome	ADJ
aji-178	362	4	-	-	PUNCT
aji-178	362	5	lysosome	lysosome	NOUN
aji-178	362	6	fusion	fusion	NOUN
aji-178	362	7	in	in	ADP
aji-178	362	8	macrophages	macrophage	NOUN
aji-178	362	9	by	by	ADP
aji-178	362	10	certain	certain	ADJ
aji-178	362	11	mycobacteria	mycobacterium	NOUN
aji-178	362	12	can	can	AUX
aji-178	362	13	be	be	AUX
aji-178	362	14	explained	explain	VERB
aji-178	362	15	by	by	ADP
aji-178	362	16	inhibition	inhibition	NOUN
aji-178	362	17	of	of	ADP
aji-178	362	18	lysosomal	lysosomal	ADJ
aji-178	362	19	movements	movement	NOUN
aji-178	362	20	observed	observe	VERB
aji-178	362	21	after	after	ADP
aji-178	362	22	phagocytosis	phagocytosis	NOUN
aji-178	362	23	.	.	PUNCT
aji-178	363	1	the	the	DET
aji-178	363	2	journal	journal	NOUN
aji-178	363	3	of	of	ADP
aji-178	363	4	experimental	experimental	ADJ
aji-178	363	5	medicine	medicine	NOUN
aji-178	363	6	,	,	PUNCT
aji-178	363	7	166(4	166(4	NUM
aji-178	363	8	)	)	PUNCT
aji-178	363	9	,	,	PUNCT
aji-178	363	10	933–946	933–946	NUM
aji-178	363	11	.	.	PUNCT
aji-178	364	1	heo	heo	PROPN
aji-178	364	2	,	,	PUNCT
aji-178	364	3	l.	l.	PROPN
aji-178	364	4	,	,	PUNCT
aji-178	364	5	park	park	PROPN
aji-178	364	6	,	,	PUNCT
aji-178	364	7	h.	h.	PROPN
aji-178	364	8	,	,	PUNCT
aji-178	364	9	&	&	CCONJ
aji-178	364	10	seok	seok	PROPN
aji-178	364	11	,	,	PUNCT
aji-178	364	12	c.	c.	PROPN
aji-178	364	13	(	(	PUNCT
aji-178	364	14	2013	2013	NUM
aji-178	364	15	)	)	PUNCT
aji-178	364	16	.	.	PUNCT
aji-178	365	1	galaxyrefine	galaxyrefine	NOUN
aji-178	365	2	:	:	PUNCT
aji-178	365	3	protein	protein	NOUN
aji-178	365	4	structure	structure	NOUN
aji-178	365	5	refinement	refinement	NOUN
aji-178	365	6	driven	drive	VERB
aji-178	365	7	by	by	ADP
aji-178	365	8	side	side	NOUN
aji-178	365	9	-	-	PUNCT
aji-178	365	10	chain	chain	NOUN
aji-178	365	11	repacking	repacking	NOUN
aji-178	365	12	.	.	PUNCT
aji-178	366	1	nucleic	nucleic	ADJ
aji-178	366	2	acids	acid	NOUN
aji-178	366	3	research	research	NOUN
aji-178	366	4	,	,	PUNCT
aji-178	366	5	41(w1	41(w1	NOUN
aji-178	366	6	)	)	PUNCT
aji-178	366	7	,	,	PUNCT
aji-178	366	8	w384	w384	PROPN
aji-178	366	9	–	–	PUNCT
aji-178	366	10	w388	w388	PROPN
aji-178	366	11	.	.	PUNCT
aji-178	366	12	hougardy	hougardy	PROPN
aji-178	366	13	,	,	PUNCT
aji-178	366	14	j.-m	j.-m	PROPN
aji-178	366	15	.	.	PUNCT
aji-178	366	16	,	,	PUNCT
aji-178	366	17	schepers	scheper	NOUN
aji-178	366	18	,	,	PUNCT
aji-178	366	19	k.	k.	PROPN
aji-178	366	20	,	,	PUNCT
aji-178	366	21	place	place	NOUN
aji-178	366	22	,	,	PUNCT
aji-178	366	23	s.	s.	PROPN
aji-178	366	24	,	,	PUNCT
aji-178	366	25	drowart	drowart	PROPN
aji-178	366	26	,	,	PUNCT
aji-178	366	27	a.	a.	NOUN
aji-178	366	28	,	,	PUNCT
aji-178	366	29	lechevin	lechevin	NOUN
aji-178	366	30	,	,	PUNCT
aji-178	366	31	v.	v.	ADJ
aji-178	366	32	,	,	PUNCT
aji-178	366	33	verscheure	verscheure	NOUN
aji-178	366	34	,	,	PUNCT
aji-178	366	35	v.	v.	ADV
aji-178	366	36	,	,	PUNCT
aji-178	366	37	debrie	debrie	NOUN
aji-178	366	38	,	,	PUNCT
aji-178	366	39	a.-s	a.-	NOUN
aji-178	366	40	.	.	PUNCT
aji-178	366	41	,	,	PUNCT
aji-178	366	42	et	et	PROPN
aji-178	366	43	al	al	PROPN
aji-178	366	44	.	.	PUNCT
aji-178	366	45	(	(	PUNCT
aji-178	366	46	2007	2007	NUM
aji-178	366	47	)	)	PUNCT
aji-178	366	48	.	.	PUNCT
aji-178	367	1	heparinbinding	heparinbinde	VERB
aji-178	367	2	-	-	PUNCT
aji-178	367	3	hemagglutinin	hemagglutinin	ADV
aji-178	367	4	-	-	PUNCT
aji-178	367	5	induced	induce	VERB
aji-178	367	6	ifn	ifn	NOUN
aji-178	367	7	-	-	PUNCT
aji-178	367	8	γ	γ	NOUN
aji-178	367	9	release	release	NOUN
aji-178	367	10	as	as	ADP
aji-178	367	11	a	a	DET
aji-178	367	12	diagnostic	diagnostic	ADJ
aji-178	367	13	tool	tool	NOUN
aji-178	367	14	for	for	ADP
aji-178	367	15	latent	latent	NOUN
aji-178	367	16	tuberculosis	tuberculosis	NOUN
aji-178	367	17	.	.	PUNCT
aji-178	368	1	plos	plos	PROPN
aji-178	368	2	one	one	NUM
aji-178	368	3	,	,	PUNCT
aji-178	368	4	2(10	2(10	NUM
aji-178	368	5	)	)	PUNCT
aji-178	368	6	,	,	PUNCT
aji-178	368	7	e926	e926	PROPN
aji-178	368	8	.	.	PUNCT
aji-178	368	9	jung	jung	PROPN
aji-178	368	10	,	,	PUNCT
aji-178	368	11	i.	i.	PROPN
aji-178	368	12	d.	d.	PROPN
aji-178	368	13	,	,	PUNCT
aji-178	368	14	jeong	jeong	PROPN
aji-178	368	15	,	,	PUNCT
aji-178	368	16	s.	s.	PROPN
aji-178	368	17	k.	k.	PROPN
aji-178	368	18	,	,	PUNCT
aji-178	368	19	lee	lee	PROPN
aji-178	368	20	,	,	PUNCT
aji-178	368	21	c.-m	c.-m	PROPN
aji-178	368	22	.	.	PROPN
aji-178	368	23	,	,	PUNCT
aji-178	368	24	noh	noh	PROPN
aji-178	368	25	,	,	PUNCT
aji-178	368	26	k.	k.	PROPN
aji-178	368	27	t.	t.	PROPN
aji-178	368	28	,	,	PUNCT
aji-178	368	29	heo	heo	PROPN
aji-178	368	30	,	,	PUNCT
aji-178	368	31	d.	d.	PROPN
aji-178	368	32	r.	r.	PROPN
aji-178	368	33	,	,	PUNCT
aji-178	368	34	shin	shin	PROPN
aji-178	368	35	,	,	PUNCT
aji-178	368	36	y.	y.	PROPN
aji-178	368	37	k.	k.	PROPN
aji-178	368	38	,	,	PUNCT
aji-178	368	39	yun	yun	PROPN
aji-178	368	40	,	,	PUNCT
aji-178	368	41	c.-h	c.-h	PROPN
aji-178	368	42	.	.	PUNCT
aji-178	368	43	,	,	PUNCT
aji-178	368	44	et	et	PROPN
aji-178	368	45	al	al	PROPN
aji-178	368	46	.	.	PROPN
aji-178	368	47	naseema	naseema	PROPN
aji-178	368	48	;	;	PUNCT
aji-178	368	49	asian	asian	PROPN
aji-178	368	50	j.	j.	PROPN
aji-178	368	51	immunol	immunol	PROPN
aji-178	368	52	.	.	PROPN
aji-178	368	53	,	,	PUNCT
aji-178	368	54	vol	vol	NOUN
aji-178	368	55	.	.	PROPN
aji-178	368	56	8	8	NUM
aji-178	368	57	,	,	PUNCT
aji-178	368	58	no	no	INTJ
aji-178	368	59	.	.	NOUN
aji-178	368	60	1	1	NUM
aji-178	368	61	,	,	PUNCT
aji-178	368	62	pp	pp	ADJ
aji-178	368	63	.	.	PUNCT
aji-178	369	1	269	269	NUM
aji-178	369	2	-	-	SYM
aji-178	369	3	284	284	NUM
aji-178	369	4	,	,	PUNCT
aji-178	369	5	2025	2025	NUM
aji-178	369	6	;	;	PUNCT
aji-178	369	7	article	article	NOUN
aji-178	369	8	no.aji.147582	no.aji.147582	PROPN
aji-178	369	9	280	280	NUM
aji-178	369	10	(	(	PUNCT
aji-178	369	11	2011	2011	NUM
aji-178	369	12	)	)	PUNCT
aji-178	369	13	.	.	PUNCT
aji-178	370	1	enhanced	enhance	VERB
aji-178	370	2	efficacy	efficacy	NOUN
aji-178	370	3	of	of	ADP
aji-178	370	4	therapeutic	therapeutic	ADJ
aji-178	370	5	cancer	cancer	NOUN
aji-178	370	6	vaccines	vaccine	NOUN
aji-178	370	7	produced	produce	VERB
aji-178	370	8	by	by	ADP
aji-178	370	9	co	co	NOUN
aji-178	370	10	-	-	NOUN
aji-178	370	11	treatment	treatment	NOUN
aji-178	370	12	with	with	ADP
aji-178	370	13	mycobacterium	mycobacterium	NOUN
aji-178	370	14	tuberculosis	tuberculosis	NOUN
aji-178	370	15	heparinbinding	heparinbinde	VERB
aji-178	370	16	hemagglutinin	hemagglutinin	NOUN
aji-178	370	17	,	,	PUNCT
aji-178	370	18	a	a	DET
aji-178	370	19	novel	novel	ADJ
aji-178	370	20	tlr4	tlr4	NOUN
aji-178	370	21	agonist	agonist	NOUN
aji-178	370	22	.	.	PUNCT
aji-178	371	1	cancer	cancer	NOUN
aji-178	371	2	research	research	NOUN
aji-178	371	3	,	,	PUNCT
aji-178	371	4	71(8	71(8	NUM
aji-178	371	5	)	)	PUNCT
aji-178	371	6	,	,	PUNCT
aji-178	371	7	2858	2858	NUM
aji-178	371	8	–	–	PUNCT
aji-178	371	9	2870	2870	NUM
aji-178	371	10	.	.	PUNCT
aji-178	372	1	kelley	kelley	PROPN
aji-178	372	2	,	,	PUNCT
aji-178	372	3	l.	l.	PROPN
aji-178	372	4	a.	a.	PROPN
aji-178	372	5	,	,	PUNCT
aji-178	372	6	mezulis	mezulis	PROPN
aji-178	372	7	,	,	PUNCT
aji-178	372	8	s.	s.	PROPN
aji-178	372	9	,	,	PUNCT
aji-178	372	10	yates	yates	PROPN
aji-178	372	11	,	,	PUNCT
aji-178	372	12	c.	c.	PROPN
aji-178	372	13	m.	m.	NOUN
aji-178	372	14	,	,	PUNCT
aji-178	372	15	wass	wass	NOUN
aji-178	372	16	,	,	PUNCT
aji-178	372	17	m.	m.	NOUN
aji-178	372	18	n.	n.	PROPN
aji-178	372	19	,	,	PUNCT
aji-178	372	20	&	&	CCONJ
aji-178	372	21	sternberg	sternberg	PROPN
aji-178	372	22	,	,	PUNCT
aji-178	372	23	m.	m.	PROPN
aji-178	372	24	j.	j.	PROPN
aji-178	372	25	e.	e.	PROPN
aji-178	372	26	(	(	PUNCT
aji-178	372	27	2015	2015	NUM
aji-178	372	28	)	)	PUNCT
aji-178	372	29	.	.	PUNCT
aji-178	373	1	the	the	DET
aji-178	373	2	phyre2	phyre2	PROPN
aji-178	373	3	web	web	NOUN
aji-178	373	4	portal	portal	NOUN
aji-178	373	5	for	for	ADP
aji-178	373	6	protein	protein	NOUN
aji-178	373	7	modeling	modeling	NOUN
aji-178	373	8	,	,	PUNCT
aji-178	373	9	prediction	prediction	NOUN
aji-178	373	10	and	and	CCONJ
aji-178	373	11	analysis	analysis	NOUN
aji-178	373	12	.	.	PUNCT
aji-178	374	1	nature	nature	NOUN
aji-178	374	2	protocols	protocol	NOUN
aji-178	374	3	,	,	PUNCT
aji-178	374	4	10(6	10(6	ADJ
aji-178	374	5	)	)	PUNCT
aji-178	374	6	,	,	PUNCT
aji-178	374	7	845–858	845–858	NUM
aji-178	374	8	.	.	PUNCT
aji-178	375	1	kim	kim	PROPN
aji-178	375	2	,	,	PUNCT
aji-178	375	3	w.	w.	PROPN
aji-178	375	4	s.	s.	PROPN
aji-178	375	5	,	,	PUNCT
aji-178	375	6	jung	jung	PROPN
aji-178	375	7	,	,	PUNCT
aji-178	375	8	i.	i.	PROPN
aji-178	375	9	d.	d.	PROPN
aji-178	375	10	,	,	PUNCT
aji-178	375	11	kim	kim	PROPN
aji-178	375	12	,	,	PUNCT
aji-178	375	13	j.-s	j.-s	PROPN
aji-178	375	14	.	.	PUNCT
aji-178	375	15	,	,	PUNCT
aji-178	375	16	kim	kim	PROPN
aji-178	375	17	,	,	PUNCT
aji-178	375	18	h.	h.	PROPN
aji-178	375	19	m.	m.	PROPN
aji-178	375	20	,	,	PUNCT
aji-178	375	21	kwon	kwon	PROPN
aji-178	375	22	,	,	PUNCT
aji-178	375	23	k.	k.	PROPN
aji-178	375	24	w.	w.	PROPN
aji-178	375	25	,	,	PUNCT
aji-178	375	26	park	park	NOUN
aji-178	375	27	,	,	PUNCT
aji-178	375	28	y.-m	y.-m	NOUN
aji-178	375	29	.	.	PROPN
aji-178	375	30	,	,	PUNCT
aji-178	375	31	&	&	CCONJ
aji-178	375	32	shin	shin	PROPN
aji-178	375	33	,	,	PUNCT
aji-178	375	34	s.	s.	PROPN
aji-178	375	35	j.	j.	PROPN
aji-178	375	36	(	(	PUNCT
aji-178	375	37	2018	2018	NUM
aji-178	375	38	)	)	PUNCT
aji-178	375	39	.	.	PUNCT
aji-178	376	1	mycobacterium	mycobacterium	NOUN
aji-178	376	2	tuberculosis	tuberculosis	PROPN
aji-178	376	3	grpe	grpe	PROPN
aji-178	376	4	,	,	PUNCT
aji-178	376	5	a	a	DET
aji-178	376	6	heat	heat	NOUN
aji-178	376	7	-	-	PUNCT
aji-178	376	8	shock	shock	NOUN
aji-178	376	9	stress	stress	NOUN
aji-178	376	10	responsive	responsive	ADJ
aji-178	376	11	chaperone	chaperone	NOUN
aji-178	376	12	,	,	PUNCT
aji-178	376	13	promotes	promote	VERB
aji-178	376	14	th1	th1	ADJ
aji-178	376	15	-	-	PUNCT
aji-178	376	16	biased	bias	VERB
aji-178	376	17	t	t	NOUN
aji-178	376	18	cell	cell	NOUN
aji-178	376	19	immune	immune	ADJ
aji-178	376	20	response	response	NOUN
aji-178	376	21	via	via	ADP
aji-178	376	22	tlr4	tlr4	NOUN
aji-178	376	23	-	-	PUNCT
aji-178	376	24	mediated	mediate	VERB
aji-178	376	25	activation	activation	NOUN
aji-178	376	26	of	of	ADP
aji-178	376	27	dendritic	dendritic	ADJ
aji-178	376	28	cells	cell	NOUN
aji-178	376	29	.	.	PUNCT
aji-178	377	1	frontiers	frontier	NOUN
aji-178	377	2	in	in	ADP
aji-178	377	3	cellular	cellular	ADJ
aji-178	377	4	and	and	CCONJ
aji-178	377	5	infection	infection	NOUN
aji-178	377	6	microbiology	microbiology	NOUN
aji-178	377	7	,	,	PUNCT
aji-178	377	8	8	8	NUM
aji-178	377	9	,	,	PUNCT
aji-178	377	10	95	95	NUM
aji-178	377	11	.	.	PUNCT
aji-178	378	1	lee	lee	PROPN
aji-178	378	2	,	,	PUNCT
aji-178	378	3	s.	s.	PROPN
aji-178	378	4	j.	j.	PROPN
aji-178	378	5	,	,	PUNCT
aji-178	378	6	shin	shin	PROPN
aji-178	378	7	,	,	PUNCT
aji-178	378	8	s.	s.	PROPN
aji-178	378	9	j.	j.	PROPN
aji-178	378	10	,	,	PUNCT
aji-178	378	11	lee	lee	PROPN
aji-178	378	12	,	,	PUNCT
aji-178	378	13	m.	m.	PROPN
aji-178	378	14	h.	h.	PROPN
aji-178	378	15	,	,	PUNCT
aji-178	378	16	lee	lee	PROPN
aji-178	378	17	,	,	PUNCT
aji-178	378	18	m.-g	m.-g	PROPN
aji-178	378	19	.	.	PROPN
aji-178	378	20	,	,	PUNCT
aji-178	378	21	kang	kang	PROPN
aji-178	378	22	,	,	PUNCT
aji-178	378	23	t.	t.	PROPN
aji-178	378	24	h.	h.	PROPN
aji-178	378	25	,	,	PUNCT
aji-178	378	26	park	park	PROPN
aji-178	378	27	,	,	PUNCT
aji-178	378	28	w.	w.	PROPN
aji-178	378	29	s.	s.	PROPN
aji-178	378	30	,	,	PUNCT
aji-178	378	31	soh	soh	PROPN
aji-178	378	32	,	,	PUNCT
aji-178	378	33	b.	b.	PROPN
aji-178	378	34	y.	y.	PROPN
aji-178	378	35	,	,	PUNCT
aji-178	378	36	et	et	PROPN
aji-178	378	37	al	al	PROPN
aji-178	378	38	.	.	PUNCT
aji-178	378	39	(	(	PUNCT
aji-178	378	40	2014	2014	NUM
aji-178	378	41	)	)	PUNCT
aji-178	378	42	.	.	PUNCT
aji-178	379	1	a	a	DET
aji-178	379	2	potential	potential	ADJ
aji-178	379	3	protein	protein	NOUN
aji-178	379	4	adjuvant	adjuvant	NOUN
aji-178	379	5	derived	derive	VERB
aji-178	379	6	from	from	ADP
aji-178	379	7	mycobacterium	mycobacterium	NOUN
aji-178	379	8	tuberculosis	tuberculosis	NOUN
aji-178	379	9	rv0652	rv0652	NOUN
aji-178	379	10	enhances	enhance	VERB
aji-178	379	11	dendritic	dendritic	ADJ
aji-178	379	12	cells	cell	NOUN
aji-178	379	13	-	-	PUNCT
aji-178	379	14	based	base	VERB
aji-178	379	15	tumor	tumor	NOUN
aji-178	379	16	immunotherapy	immunotherapy	NOUN
aji-178	379	17	.	.	PUNCT
aji-178	380	1	plos	plos	PROPN
aji-178	380	2	one	one	NUM
aji-178	380	3	,	,	PUNCT
aji-178	380	4	9(8	9(8	NUM
aji-178	380	5	)	)	PUNCT
aji-178	380	6	,	,	PUNCT
aji-178	380	7	e104351	e104351	PROPN
aji-178	380	8	.	.	PUNCT
aji-178	380	9	mangtani	mangtani	PROPN
aji-178	380	10	,	,	PUNCT
aji-178	380	11	p.	p.	NOUN
aji-178	380	12	,	,	PUNCT
aji-178	380	13	abubakar	abubakar	PROPN
aji-178	380	14	,	,	PUNCT
aji-178	380	15	i.	i.	PROPN
aji-178	380	16	,	,	PUNCT
aji-178	380	17	ariti	ariti	PROPN
aji-178	380	18	,	,	PUNCT
aji-178	380	19	c.	c.	PROPN
aji-178	380	20	,	,	PUNCT
aji-178	380	21	beynon	beynon	PROPN
aji-178	380	22	,	,	PUNCT
aji-178	380	23	r.	r.	PROPN
aji-178	380	24	,	,	PUNCT
aji-178	380	25	pimpin	pimpin	NOUN
aji-178	380	26	,	,	PUNCT
aji-178	380	27	l.	l.	PROPN
aji-178	380	28	,	,	PUNCT
aji-178	380	29	fine	fine	ADJ
aji-178	380	30	,	,	PUNCT
aji-178	381	1	p.	p.	PROPN
aji-178	381	2	e.	e.	PROPN
aji-178	381	3	m.	m.	PROPN
aji-178	381	4	,	,	PUNCT
aji-178	381	5	rodrigues	rodrigues	PROPN
aji-178	381	6	,	,	PUNCT
aji-178	381	7	l.	l.	PROPN
aji-178	381	8	c.	c.	PROPN
aji-178	381	9	,	,	PUNCT
aji-178	381	10	et	et	PROPN
aji-178	381	11	al	al	PROPN
aji-178	381	12	.	.	PUNCT
aji-178	381	13	(	(	PUNCT
aji-178	381	14	2014	2014	NUM
aji-178	381	15	)	)	PUNCT
aji-178	381	16	.	.	PUNCT
aji-178	382	1	protection	protection	NOUN
aji-178	382	2	by	by	ADP
aji-178	382	3	bcg	bcg	PROPN
aji-178	382	4	vaccine	vaccine	NOUN
aji-178	382	5	against	against	ADP
aji-178	382	6	tuberculosis	tuberculosis	NOUN
aji-178	382	7	:	:	PUNCT
aji-178	382	8	a	a	DET
aji-178	382	9	systematic	systematic	ADJ
aji-178	382	10	review	review	NOUN
aji-178	382	11	of	of	ADP
aji-178	382	12	randomized	randomized	ADJ
aji-178	382	13	controlled	control	VERB
aji-178	382	14	trials	trial	NOUN
aji-178	382	15	.	.	PUNCT
aji-178	383	1	clinical	clinical	ADJ
aji-178	383	2	infectious	infectious	ADJ
aji-178	383	3	diseases	disease	NOUN
aji-178	383	4	,	,	PUNCT
aji-178	383	5	58(4	58(4	NUM
aji-178	383	6	)	)	PUNCT
aji-178	383	7	,	,	PUNCT
aji-178	383	8	470–480	470–480	NUM
aji-178	383	9	.	.	PUNCT
aji-178	384	1	martinot	martinot	ADV
aji-178	384	2	,	,	PUNCT
aji-178	384	3	a.	a.	PROPN
aji-178	384	4	j.	j.	PROPN
aji-178	384	5	,	,	PUNCT
aji-178	384	6	farrow	farrow	PROPN
aji-178	384	7	,	,	PUNCT
aji-178	384	8	m.	m.	NOUN
aji-178	384	9	,	,	PUNCT
aji-178	384	10	bai	bai	PROPN
aji-178	384	11	,	,	PUNCT
aji-178	384	12	l.	l.	PROPN
aji-178	384	13	,	,	PUNCT
aji-178	384	14	layre	layre	PROPN
aji-178	384	15	,	,	PUNCT
aji-178	384	16	e.	e.	PROPN
aji-178	384	17	,	,	PUNCT
aji-178	384	18	cheng	cheng	PROPN
aji-178	384	19	,	,	PUNCT
aji-178	384	20	t.-y	t.-y	PROPN
aji-178	384	21	.	.	PROPN
aji-178	384	22	,	,	PUNCT
aji-178	384	23	tsai	tsai	PROPN
aji-178	384	24	,	,	PUNCT
aji-178	384	25	j.	j.	PROPN
aji-178	384	26	h.	h.	PROPN
aji-178	384	27	,	,	PUNCT
aji-178	384	28	iqbal	iqbal	PROPN
aji-178	384	29	,	,	PUNCT
aji-178	384	30	j.	j.	PROPN
aji-178	384	31	,	,	PUNCT
aji-178	384	32	et	et	PROPN
aji-178	384	33	al	al	PROPN
aji-178	384	34	.	.	PUNCT
aji-178	385	1	(	(	PUNCT
aji-178	385	2	2016	2016	NUM
aji-178	385	3	)	)	PUNCT
aji-178	385	4	.	.	PUNCT
aji-178	386	1	mycobacterial	mycobacterial	ADJ
aji-178	386	2	metabolic	metabolic	NOUN
aji-178	386	3	syndrome	syndrome	NOUN
aji-178	386	4	:	:	PUNCT
aji-178	386	5	lprg	lprg	PROPN
aji-178	386	6	and	and	CCONJ
aji-178	386	7	rv1410	rv1410	ADJ
aji-178	386	8	regulate	regulate	VERB
aji-178	386	9	triacylglyceride	triacylglyceride	NOUN
aji-178	386	10	levels	level	NOUN
aji-178	386	11	,	,	PUNCT
aji-178	386	12	growth	growth	NOUN
aji-178	386	13	rate	rate	NOUN
aji-178	386	14	and	and	CCONJ
aji-178	386	15	virulence	virulence	NOUN
aji-178	386	16	in	in	ADP
aji-178	386	17	mycobacterium	mycobacterium	NOUN
aji-178	386	18	tuberculosis	tuberculosis	NOUN
aji-178	386	19	.	.	PUNCT
aji-178	387	1	plos	plos	PROPN
aji-178	387	2	pathogens	pathogens	PROPN
aji-178	387	3	,	,	PUNCT
aji-178	387	4	12(1	12(1	NUM
aji-178	387	5	)	)	PUNCT
aji-178	387	6	,	,	PUNCT
aji-178	387	7	e1005351	e1005351	PROPN
aji-178	387	8	.	.	PROPN
aji-178	387	9	mehla	mehla	PROPN
aji-178	387	10	,	,	PUNCT
aji-178	387	11	k.	k.	PROPN
aji-178	387	12	,	,	PUNCT
aji-178	387	13	&	&	CCONJ
aji-178	387	14	ramana	ramana	PROPN
aji-178	387	15	,	,	PUNCT
aji-178	387	16	j.	j.	PROPN
aji-178	387	17	(	(	PUNCT
aji-178	387	18	2016	2016	NUM
aji-178	387	19	)	)	PUNCT
aji-178	387	20	.	.	PUNCT
aji-178	388	1	identification	identification	NOUN
aji-178	388	2	of	of	ADP
aji-178	388	3	epitope	epitope	NOUN
aji-178	388	4	-	-	PUNCT
aji-178	388	5	based	base	VERB
aji-178	388	6	peptide	peptide	NOUN
aji-178	388	7	vaccine	vaccine	NOUN
aji-178	388	8	candidates	candidate	NOUN
aji-178	388	9	against	against	ADP
aji-178	388	10	enterotoxigenic	enterotoxigenic	ADJ
aji-178	388	11	escherichia	escherichia	NOUN
aji-178	388	12	coli	coli	NOUN
aji-178	388	13	:	:	PUNCT
aji-178	388	14	a	a	DET
aji-178	388	15	comparative	comparative	ADJ
aji-178	388	16	genomics	genomic	NOUN
aji-178	388	17	and	and	CCONJ
aji-178	388	18	immunoinformatics	immunoinformatic	NOUN
aji-178	388	19	approach	approach	NOUN
aji-178	388	20	.	.	PUNCT
aji-178	389	1	molecular	molecular	ADJ
aji-178	389	2	biosystems	biosystem	NOUN
aji-178	389	3	,	,	PUNCT
aji-178	389	4	12(3	12(3	NUM
aji-178	389	5	)	)	PUNCT
aji-178	389	6	,	,	PUNCT
aji-178	389	7	890–901	890–901	NUM
aji-178	389	8	.	.	PUNCT
aji-178	390	1	mustafa	mustafa	PROPN
aji-178	390	2	,	,	PUNCT
aji-178	390	3	a.	a.	PROPN
aji-178	390	4	s.	s.	PROPN
aji-178	390	5	(	(	PUNCT
aji-178	390	6	2002	2002	NUM
aji-178	390	7	)	)	PUNCT
aji-178	390	8	.	.	PUNCT
aji-178	391	1	development	development	NOUN
aji-178	391	2	of	of	ADP
aji-178	391	3	new	new	ADJ
aji-178	391	4	vaccines	vaccine	NOUN
aji-178	391	5	and	and	CCONJ
aji-178	391	6	diagnostic	diagnostic	ADJ
aji-178	391	7	reagents	reagent	NOUN
aji-178	391	8	against	against	ADP
aji-178	391	9	tuberculosis	tuberculosis	NOUN
aji-178	391	10	.	.	PUNCT
aji-178	392	1	molecular	molecular	ADJ
aji-178	392	2	immunology	immunology	NOUN
aji-178	392	3	,	,	PUNCT
aji-178	392	4	39(1	39(1	NUM
aji-178	392	5	–	–	PUNCT
aji-178	392	6	2	2	NUM
aji-178	392	7	)	)	PUNCT
aji-178	392	8	,	,	PUNCT
aji-178	392	9	113–119	113–119	NUM
aji-178	392	10	.	.	PUNCT
aji-178	392	11	nagpal	nagpal	PROPN
aji-178	392	12	,	,	PUNCT
aji-178	392	13	p.	p.	NOUN
aji-178	392	14	,	,	PUNCT
aji-178	392	15	jamal	jamal	PROPN
aji-178	392	16	,	,	PUNCT
aji-178	392	17	s.	s.	PROPN
aji-178	392	18	,	,	PUNCT
aji-178	392	19	singh	singh	PROPN
aji-178	392	20	,	,	PUNCT
aji-178	392	21	h.	h.	PROPN
aji-178	392	22	,	,	PUNCT
aji-178	392	23	ali	ali	PROPN
aji-178	392	24	,	,	PUNCT
aji-178	392	25	w.	w.	PROPN
aji-178	392	26	,	,	PUNCT
aji-178	392	27	tanweer	tanweer	PROPN
aji-178	392	28	,	,	PUNCT
aji-178	392	29	s.	s.	PROPN
aji-178	392	30	,	,	PUNCT
aji-178	392	31	sharma	sharma	PROPN
aji-178	392	32	,	,	PUNCT
aji-178	392	33	r.	r.	PROPN
aji-178	392	34	,	,	PUNCT
aji-178	392	35	grover	grover	PROPN
aji-178	392	36	,	,	PUNCT
aji-178	392	37	a.	a.	PROPN
aji-178	392	38	,	,	PUNCT
aji-178	392	39	&	&	CCONJ
aji-178	392	40	grover	grover	PROPN
aji-178	392	41	,	,	PUNCT
aji-178	392	42	s.	s.	PROPN
aji-178	392	43	(	(	PUNCT
aji-178	392	44	2020	2020	NUM
aji-178	392	45	)	)	PUNCT
aji-178	392	46	.	.	PUNCT
aji-178	393	1	long	long	ADJ
aji-178	393	2	-	-	PUNCT
aji-178	393	3	range	range	NOUN
aji-178	393	4	replica	replica	NOUN
aji-178	393	5	exchange	exchange	NOUN
aji-178	393	6	molecular	molecular	ADJ
aji-178	393	7	dynamics	dynamic	NOUN
aji-178	393	8	guided	guide	VERB
aji-178	393	9	drug	drug	NOUN
aji-178	393	10	repurposing	repurpose	VERB
aji-178	393	11	against	against	ADP
aji-178	393	12	tyrosine	tyrosine	NOUN
aji-178	393	13	kinase	kinase	PROPN
aji-178	393	14	ptka	ptka	PROPN
aji-178	393	15	of	of	ADP
aji-178	393	16	mycobacterium	mycobacterium	NOUN
aji-178	393	17	tuberculosis	tuberculosis	NOUN
aji-178	393	18	.	.	PUNCT
aji-178	394	1	scientific	scientific	ADJ
aji-178	394	2	reports	report	NOUN
aji-178	394	3	,	,	PUNCT
aji-178	394	4	10(1	10(1	NUM
aji-178	394	5	)	)	PUNCT
aji-178	394	6	,	,	PUNCT
aji-178	394	7	1–11	1–11	PROPN
aji-178	394	8	.	.	PUNCT
aji-178	395	1	nayak	nayak	PROPN
aji-178	395	2	,	,	PUNCT
aji-178	395	3	s.	s.	PROPN
aji-178	395	4	s.	s.	PROPN
aji-178	395	5	,	,	PUNCT
aji-178	395	6	sethi	sethi	PROPN
aji-178	395	7	,	,	PUNCT
aji-178	395	8	g.	g.	PROPN
aji-178	395	9	,	,	PUNCT
aji-178	395	10	&	&	CCONJ
aji-178	395	11	ramadas	ramadas	PROPN
aji-178	395	12	,	,	PUNCT
aji-178	395	13	k.	k.	PROPN
aji-178	395	14	(	(	PUNCT
aji-178	395	15	2023	2023	NUM
aji-178	395	16	)	)	PUNCT
aji-178	395	17	.	.	PUNCT
aji-178	396	1	design	design	NOUN
aji-178	396	2	of	of	ADP
aji-178	396	3	multi	multi	ADJ
aji-178	396	4	-	-	ADJ
aji-178	396	5	epitope	epitope	ADJ
aji-178	396	6	based	base	VERB
aji-178	396	7	vaccine	vaccine	NOUN
aji-178	396	8	against	against	ADP
aji-178	396	9	mycobacterium	mycobacterium	NOUN
aji-178	396	10	tuberculosis	tuberculosis	NOUN
aji-178	396	11	:	:	PUNCT
aji-178	396	12	a	a	DET
aji-178	396	13	subtractive	subtractive	NOUN
aji-178	396	14	proteomics	proteomic	NOUN
aji-178	396	15	and	and	CCONJ
aji-178	396	16	reverse	reverse	ADJ
aji-178	396	17	vaccinology	vaccinology	NOUN
aji-178	396	18	based	base	VERB
aji-178	396	19	immunoinformatics	immunoinformatic	NOUN
aji-178	396	20	approach	approach	NOUN
aji-178	396	21	.	.	PUNCT
aji-178	397	1	journal	journal	NOUN
aji-178	397	2	of	of	ADP
aji-178	397	3	biomolecular	biomolecular	ADJ
aji-178	397	4	structure	structure	NOUN
aji-178	397	5	and	and	CCONJ
aji-178	397	6	dynamics	dynamic	NOUN
aji-178	397	7	,	,	PUNCT
aji-178	397	8	41(23	41(23	NOUN
aji-178	397	9	)	)	PUNCT
aji-178	397	10	,	,	PUNCT
aji-178	397	11	14116	14116	NUM
aji-178	397	12	–	–	PUNCT
aji-178	397	13	14134	14134	NUM
aji-178	397	14	.	.	PUNCT
aji-178	398	1	pablos	pablos	PROPN
aji-178	398	2	-	-	PUNCT
aji-178	398	3	mendez	mendez	PROPN
aji-178	398	4	,	,	PUNCT
aji-178	398	5	a.	a.	PROPN
aji-178	398	6	,	,	PUNCT
aji-178	398	7	gowda	gowda	PROPN
aji-178	398	8	,	,	PUNCT
aji-178	398	9	d.	d.	PROPN
aji-178	398	10	k.	k.	PROPN
aji-178	398	11	,	,	PUNCT
aji-178	398	12	&	&	CCONJ
aji-178	398	13	frieden	frieden	PROPN
aji-178	398	14	,	,	PUNCT
aji-178	398	15	t.	t.	PROPN
aji-178	398	16	r.	r.	PROPN
aji-178	398	17	(	(	PUNCT
aji-178	398	18	2002	2002	NUM
aji-178	398	19	)	)	PUNCT
aji-178	398	20	.	.	PUNCT
aji-178	399	1	controlling	control	VERB
aji-178	399	2	multidrug	multidrug	NOUN
aji-178	399	3	-	-	PUNCT
aji-178	399	4	resistant	resistant	ADJ
aji-178	399	5	tuberculosis	tuberculosis	NOUN
aji-178	399	6	and	and	CCONJ
aji-178	399	7	access	access	NOUN
aji-178	399	8	to	to	ADP
aji-178	399	9	expensive	expensive	ADJ
aji-178	399	10	drugs	drug	NOUN
aji-178	399	11	:	:	PUNCT
aji-178	399	12	a	a	DET
aji-178	399	13	rational	rational	ADJ
aji-178	399	14	framework	framework	NOUN
aji-178	399	15	.	.	PUNCT
aji-178	400	1	bulletin	bulletin	NOUN
aji-178	400	2	of	of	ADP
aji-178	400	3	the	the	DET
aji-178	400	4	world	world	PROPN
aji-178	400	5	health	health	PROPN
aji-178	400	6	organization	organization	NOUN
aji-178	400	7	,	,	PUNCT
aji-178	400	8	80	80	NUM
aji-178	400	9	,	,	PUNCT
aji-178	400	10	489–495	489–495	NUM
aji-178	400	11	(	(	PUNCT
aji-178	400	12	discussion	discussion	NOUN
aji-178	400	13	495–500	495–500	NUM
aji-178	400	14	)	)	PUNCT
aji-178	400	15	.	.	PUNCT
aji-178	401	1	park	park	PROPN
aji-178	401	2	,	,	PUNCT
aji-178	401	3	b.	b.	PROPN
aji-178	401	4	s.	s.	PROPN
aji-178	401	5	,	,	PUNCT
aji-178	401	6	song	song	PROPN
aji-178	401	7	,	,	PUNCT
aji-178	401	8	d.	d.	PROPN
aji-178	401	9	h.	h.	PROPN
aji-178	401	10	,	,	PUNCT
aji-178	401	11	kim	kim	PROPN
aji-178	401	12	,	,	PUNCT
aji-178	401	13	h.	h.	PROPN
aji-178	401	14	m.	m.	PROPN
aji-178	401	15	,	,	PUNCT
aji-178	401	16	choi	choi	NOUN
aji-178	401	17	,	,	PUNCT
aji-178	401	18	b.-s	b.-s	PROPN
aji-178	401	19	.	.	PUNCT
aji-178	401	20	,	,	PUNCT
aji-178	401	21	lee	lee	PROPN
aji-178	401	22	,	,	PUNCT
aji-178	401	23	h.	h.	PROPN
aji-178	401	24	,	,	PUNCT
aji-178	401	25	&	&	CCONJ
aji-178	401	26	lee	lee	PROPN
aji-178	401	27	,	,	PUNCT
aji-178	401	28	j.-o	j.-o	NOUN
aji-178	401	29	.	.	PUNCT
aji-178	402	1	(	(	PUNCT
aji-178	402	2	2009	2009	NUM
aji-178	402	3	)	)	PUNCT
aji-178	402	4	.	.	PUNCT
aji-178	403	1	the	the	DET
aji-178	403	2	structural	structural	ADJ
aji-178	403	3	basis	basis	NOUN
aji-178	403	4	of	of	ADP
aji-178	403	5	lipopolysaccharide	lipopolysaccharide	ADJ
aji-178	403	6	recognition	recognition	NOUN
aji-178	403	7	by	by	ADP
aji-178	403	8	the	the	DET
aji-178	403	9	tlr4	tlr4	NOUN
aji-178	403	10	–	–	PUNCT
aji-178	403	11	md-2	md-2	SYM
aji-178	403	12	complex	complex	ADJ
aji-178	403	13	.	.	PUNCT
aji-178	404	1	nature	nature	NOUN
aji-178	404	2	,	,	PUNCT
aji-178	404	3	458(7242	458(7242	PROPN
aji-178	404	4	)	)	PUNCT
aji-178	404	5	,	,	PUNCT
aji-178	404	6	1191–1195	1191–1195	NUM
aji-178	404	7	.	.	PUNCT
aji-178	405	1	rapin	rapin	NOUN
aji-178	405	2	,	,	PUNCT
aji-178	405	3	n.	n.	NOUN
aji-178	405	4	,	,	PUNCT
aji-178	405	5	lund	lund	PROPN
aji-178	405	6	,	,	PUNCT
aji-178	405	7	o.	o.	PROPN
aji-178	405	8	,	,	PUNCT
aji-178	405	9	bernaschi	bernaschi	NOUN
aji-178	405	10	,	,	PUNCT
aji-178	405	11	m.	m.	NOUN
aji-178	405	12	,	,	PUNCT
aji-178	405	13	&	&	CCONJ
aji-178	405	14	castiglione	castiglione	PROPN
aji-178	405	15	,	,	PUNCT
aji-178	405	16	f.	f.	PROPN
aji-178	405	17	(	(	PUNCT
aji-178	405	18	2010	2010	NUM
aji-178	405	19	)	)	PUNCT
aji-178	405	20	.	.	PUNCT
aji-178	406	1	computational	computational	ADJ
aji-178	406	2	immunology	immunology	NOUN
aji-178	406	3	meets	meet	VERB
aji-178	406	4	bioinformatics	bioinformatic	NOUN
aji-178	406	5	:	:	PUNCT
aji-178	406	6	the	the	DET
aji-178	406	7	use	use	NOUN
aji-178	406	8	of	of	ADP
aji-178	406	9	prediction	prediction	NOUN
aji-178	406	10	tools	tool	NOUN
aji-178	406	11	for	for	ADP
aji-178	406	12	molecular	molecular	ADJ
aji-178	406	13	binding	binding	NOUN
aji-178	406	14	in	in	ADP
aji-178	406	15	the	the	DET
aji-178	406	16	simulation	simulation	NOUN
aji-178	406	17	of	of	ADP
aji-178	406	18	the	the	DET
aji-178	406	19	immune	immune	ADJ
aji-178	406	20	system	system	NOUN
aji-178	406	21	.	.	PUNCT
aji-178	407	1	plos	plos	PROPN
aji-178	407	2	one	one	NUM
aji-178	407	3	,	,	PUNCT
aji-178	407	4	5(4	5(4	NUM
aji-178	407	5	)	)	PUNCT
aji-178	407	6	,	,	PUNCT
aji-178	407	7	e9862	e9862	PROPN
aji-178	407	8	.	.	PROPN
aji-178	407	9	saha	saha	PROPN
aji-178	407	10	,	,	PUNCT
aji-178	407	11	s.	s.	PROPN
aji-178	407	12	,	,	PUNCT
aji-178	407	13	&	&	CCONJ
aji-178	407	14	raghava	raghava	PROPN
aji-178	407	15	,	,	PUNCT
aji-178	407	16	g.	g.	PROPN
aji-178	407	17	p.	p.	PROPN
aji-178	407	18	s.	s.	PROPN
aji-178	407	19	(	(	PUNCT
aji-178	407	20	2006	2006	NUM
aji-178	407	21	)	)	PUNCT
aji-178	407	22	.	.	PUNCT
aji-178	408	1	prediction	prediction	NOUN
aji-178	408	2	of	of	ADP
aji-178	408	3	continuous	continuous	ADJ
aji-178	408	4	b	b	NOUN
aji-178	408	5	-	-	PUNCT
aji-178	408	6	cell	cell	NOUN
aji-178	408	7	epitopes	epitope	NOUN
aji-178	408	8	in	in	ADP
aji-178	408	9	an	an	DET
aji-178	408	10	antigen	antigen	NOUN
aji-178	408	11	using	use	VERB
aji-178	408	12	recurrent	recurrent	ADJ
aji-178	408	13	neural	neural	ADJ
aji-178	408	14	network	network	NOUN
aji-178	408	15	.	.	PUNCT
aji-178	409	1	proteins	protein	NOUN
aji-178	409	2	:	:	PUNCT
aji-178	409	3	structure	structure	NOUN
aji-178	409	4	,	,	PUNCT
aji-178	409	5	function	function	NOUN
aji-178	409	6	,	,	PUNCT
aji-178	409	7	and	and	CCONJ
aji-178	409	8	bioinformatics	bioinformatics	NOUN
aji-178	409	9	,	,	PUNCT
aji-178	409	10	65(1	65(1	NOUN
aji-178	409	11	)	)	PUNCT
aji-178	409	12	,	,	PUNCT
aji-178	409	13	40–48	40–48	NUM
aji-178	409	14	.	.	PUNCT
aji-178	410	1	sanches	sanches	PROPN
aji-178	410	2	,	,	PUNCT
aji-178	410	3	r.	r.	PROPN
aji-178	410	4	c.	c.	PROPN
aji-178	410	5	o.	o.	PROPN
aji-178	410	6	,	,	PUNCT
aji-178	410	7	tiwari	tiwari	PROPN
aji-178	410	8	,	,	PUNCT
aji-178	410	9	s.	s.	PROPN
aji-178	410	10	,	,	PUNCT
aji-178	410	11	ferreira	ferreira	PROPN
aji-178	410	12	,	,	PUNCT
aji-178	410	13	l.	l.	PROPN
aji-178	410	14	c.	c.	PROPN
aji-178	410	15	g.	g.	PROPN
aji-178	410	16	,	,	PUNCT
aji-178	410	17	oliveira	oliveira	PROPN
aji-178	410	18	,	,	PUNCT
aji-178	410	19	f.	f.	PROPN
aji-178	410	20	m.	m.	PROPN
aji-178	410	21	,	,	PUNCT
aji-178	410	22	lopes	lopes	PROPN
aji-178	410	23	,	,	PUNCT
aji-178	410	24	m.	m.	PROPN
aji-178	410	25	d.	d.	PROPN
aji-178	410	26	,	,	PUNCT
aji-178	410	27	passos	passos	PROPN
aji-178	410	28	,	,	PUNCT
aji-178	410	29	m.	m.	PROPN
aji-178	410	30	j.	j.	PROPN
aji-178	410	31	f.	f.	PROPN
aji-178	410	32	,	,	PUNCT
aji-178	410	33	maia	maia	PROPN
aji-178	410	34	,	,	PUNCT
aji-178	410	35	e.	e.	PROPN
aji-178	410	36	h.	h.	PROPN
aji-178	410	37	b.	b.	PROPN
aji-178	410	38	,	,	PUNCT
aji-178	410	39	et	et	PROPN
aji-178	410	40	al	al	PROPN
aji-178	410	41	.	.	PROPN
aji-178	410	42	(	(	PUNCT
aji-178	410	43	2021	2021	NUM
aji-178	410	44	)	)	PUNCT
aji-178	410	45	.	.	PUNCT
aji-178	411	1	immunoinformatics	immunoinformatic	NOUN
aji-178	411	2	design	design	PROPN
aji-178	411	3	of	of	ADP
aji-178	411	4	multi	multi	ADJ
aji-178	411	5	-	-	ADJ
aji-178	411	6	epitope	epitope	NOUN
aji-178	411	7	peptide	peptide	NOUN
aji-178	411	8	-	-	PUNCT
aji-178	411	9	based	base	VERB
aji-178	411	10	vaccine	vaccine	NOUN
aji-178	411	11	against	against	ADP
aji-178	411	12	schistosoma	schistosoma	ADJ
aji-178	411	13	mansoni	mansoni	ADJ
aji-178	411	14	using	use	VERB
aji-178	411	15	transmembrane	transmembrane	ADJ
aji-178	411	16	proteins	protein	NOUN
aji-178	411	17	as	as	ADP
aji-178	411	18	a	a	DET
aji-178	411	19	target	target	NOUN
aji-178	411	20	.	.	PUNCT
aji-178	412	1	frontiers	frontier	NOUN
aji-178	412	2	in	in	ADP
aji-178	412	3	immunology	immunology	NOUN
aji-178	412	4	,	,	PUNCT
aji-178	412	5	12	12	NUM
aji-178	412	6	,	,	PUNCT
aji-178	412	7	490	490	NUM
aji-178	412	8	.	.	X
aji-178	412	9	schorey	schorey	PROPN
aji-178	412	10	,	,	PUNCT
aji-178	412	11	j.	j.	PROPN
aji-178	412	12	s.	s.	PROPN
aji-178	412	13	,	,	PUNCT
aji-178	412	14	&	&	CCONJ
aji-178	412	15	harding	harding	PROPN
aji-178	412	16	,	,	PUNCT
aji-178	413	1	c.	c.	PROPN
aji-178	413	2	v.	v.	PROPN
aji-178	413	3	(	(	PUNCT
aji-178	413	4	2016	2016	NUM
aji-178	413	5	)	)	PUNCT
aji-178	413	6	.	.	PUNCT
aji-178	414	1	extracellular	extracellular	ADJ
aji-178	414	2	vesicles	vesicle	NOUN
aji-178	414	3	and	and	CCONJ
aji-178	414	4	infectious	infectious	ADJ
aji-178	414	5	diseases	disease	NOUN
aji-178	414	6	:	:	PUNCT
aji-178	414	7	new	new	ADJ
aji-178	414	8	complexity	complexity	NOUN
aji-178	414	9	to	to	ADP
aji-178	414	10	an	an	DET
aji-178	414	11	old	old	ADJ
aji-178	414	12	story	story	NOUN
aji-178	414	13	.	.	PUNCT
aji-178	415	1	the	the	DET
aji-178	415	2	journal	journal	NOUN
aji-178	415	3	of	of	ADP
aji-178	415	4	clinical	clinical	ADJ
aji-178	415	5	investigation	investigation	NOUN
aji-178	415	6	,	,	PUNCT
aji-178	415	7	126(4	126(4	NUM
aji-178	415	8	)	)	PUNCT
aji-178	415	9	,	,	PUNCT
aji-178	415	10	1181–1189	1181–1189	NUM
aji-178	415	11	.	.	PUNCT
aji-178	415	12	sharma	sharma	PROPN
aji-178	415	13	,	,	PUNCT
aji-178	415	14	r.	r.	PROPN
aji-178	415	15	,	,	PUNCT
aji-178	415	16	rajput	rajput	PROPN
aji-178	415	17	,	,	PUNCT
aji-178	415	18	v.	v.	PROPN
aji-178	415	19	s.	s.	PROPN
aji-178	415	20	,	,	PUNCT
aji-178	415	21	jamal	jamal	PROPN
aji-178	415	22	,	,	PUNCT
aji-178	415	23	s.	s.	PROPN
aji-178	415	24	,	,	PUNCT
aji-178	415	25	grover	grover	PROPN
aji-178	415	26	,	,	PUNCT
aji-178	415	27	a.	a.	PROPN
aji-178	415	28	,	,	PUNCT
aji-178	415	29	&	&	CCONJ
aji-178	415	30	grover	grover	PROPN
aji-178	415	31	,	,	PUNCT
aji-178	415	32	s.	s.	PROPN
aji-178	415	33	(	(	PUNCT
aji-178	415	34	2021	2021	NUM
aji-178	415	35	)	)	PUNCT
aji-178	415	36	.	.	PUNCT
aji-178	416	1	an	an	DET
aji-178	416	2	immunoinformatics	immunoinformatic	NOUN
aji-178	416	3	approach	approach	NOUN
aji-178	416	4	to	to	PART
aji-178	416	5	design	design	VERB
aji-178	416	6	a	a	DET
aji-178	416	7	multi	multi	ADJ
aji-178	416	8	-	-	ADJ
aji-178	416	9	epitope	epitope	ADJ
aji-178	416	10	vaccine	vaccine	NOUN
aji-178	416	11	against	against	ADP
aji-178	416	12	mycobacterium	mycobacterium	NOUN
aji-178	416	13	tuberculosis	tuberculosis	NOUN
aji-178	416	14	exploiting	exploit	VERB
aji-178	416	15	secreted	secrete	VERB
aji-178	416	16	exosome	exosome	NOUN
aji-178	416	17	proteins	protein	NOUN
aji-178	416	18	.	.	PUNCT
aji-178	417	1	scientific	scientific	ADJ
aji-178	417	2	reports	report	NOUN
aji-178	417	3	,	,	PUNCT
aji-178	417	4	11(1	11(1	NUM
aji-178	417	5	)	)	PUNCT
aji-178	417	6	,	,	PUNCT
aji-178	417	7	1–12	1–12	PROPN
aji-178	417	8	.	.	PUNCT
aji-178	418	1	trott	trott	PROPN
aji-178	418	2	,	,	PUNCT
aji-178	418	3	o.	o.	PROPN
aji-178	418	4	,	,	PUNCT
aji-178	418	5	&	&	CCONJ
aji-178	418	6	olson	olson	PROPN
aji-178	418	7	,	,	PUNCT
aji-178	418	8	a.	a.	PROPN
aji-178	418	9	j.	j.	PROPN
aji-178	418	10	(	(	PUNCT
aji-178	418	11	2010	2010	NUM
aji-178	418	12	)	)	PUNCT
aji-178	418	13	.	.	PUNCT
aji-178	419	1	autodock	autodock	PROPN
aji-178	419	2	vina	vina	PROPN
aji-178	419	3	:	:	PUNCT
aji-178	419	4	improving	improve	VERB
aji-178	419	5	the	the	DET
aji-178	419	6	speed	speed	NOUN
aji-178	419	7	and	and	CCONJ
aji-178	419	8	accuracy	accuracy	NOUN
aji-178	419	9	of	of	ADP
aji-178	419	10	docking	docking	NOUN
aji-178	419	11	with	with	ADP
aji-178	419	12	a	a	DET
aji-178	419	13	new	new	ADJ
aji-178	419	14	scoring	scoring	NOUN
aji-178	419	15	function	function	NOUN
aji-178	419	16	,	,	PUNCT
aji-178	419	17	efficient	efficient	ADJ
aji-178	419	18	optimization	optimization	NOUN
aji-178	419	19	,	,	PUNCT
aji-178	419	20	and	and	CCONJ
aji-178	419	21	multithreading	multithreade	VERB
aji-178	419	22	.	.	PUNCT
aji-178	420	1	journal	journal	NOUN
aji-178	420	2	of	of	ADP
aji-178	420	3	computational	computational	ADJ
aji-178	420	4	chemistry	chemistry	NOUN
aji-178	420	5	,	,	PUNCT
aji-178	420	6	31(2	31(2	NUM
aji-178	420	7	)	)	PUNCT
aji-178	420	8	,	,	PUNCT
aji-178	420	9	455–461	455–461	NUM
aji-178	420	10	.	.	PUNCT
aji-178	421	1	trunz	trunz	PROPN
aji-178	421	2	,	,	PUNCT
aji-178	421	3	b.	b.	PROPN
aji-178	421	4	b.	b.	PROPN
aji-178	421	5	,	,	PUNCT
aji-178	421	6	fine	fine	ADJ
aji-178	421	7	,	,	PUNCT
aji-178	421	8	p.	p.	PROPN
aji-178	421	9	e.	e.	PROPN
aji-178	421	10	m.	m.	PROPN
aji-178	421	11	,	,	PUNCT
aji-178	421	12	&	&	CCONJ
aji-178	421	13	dye	dye	PROPN
aji-178	421	14	,	,	PUNCT
aji-178	421	15	c.	c.	PROPN
aji-178	421	16	(	(	PUNCT
aji-178	421	17	2006	2006	NUM
aji-178	421	18	)	)	PUNCT
aji-178	421	19	.	.	PUNCT
aji-178	422	1	effect	effect	NOUN
aji-178	422	2	of	of	ADP
aji-178	422	3	bcg	bcg	PROPN
aji-178	422	4	vaccination	vaccination	NOUN
aji-178	422	5	on	on	ADP
aji-178	422	6	childhood	childhood	NOUN
aji-178	422	7	tuberculous	tuberculous	ADJ
aji-178	422	8	meningitis	meningitis	NOUN
aji-178	422	9	and	and	CCONJ
aji-178	422	10	miliary	miliary	ADJ
aji-178	422	11	naseema	naseema	NOUN
aji-178	422	12	;	;	PUNCT
aji-178	422	13	asian	asian	ADJ
aji-178	422	14	j.	j.	PROPN
aji-178	422	15	immunol	immunol	PROPN
aji-178	422	16	.	.	PROPN
aji-178	422	17	,	,	PUNCT
aji-178	422	18	vol	vol	NOUN
aji-178	422	19	.	.	PROPN
aji-178	422	20	8	8	NUM
aji-178	422	21	,	,	PUNCT
aji-178	422	22	no	no	INTJ
aji-178	422	23	.	.	NOUN
aji-178	422	24	1	1	NUM
aji-178	422	25	,	,	PUNCT
aji-178	422	26	pp	pp	ADJ
aji-178	422	27	.	.	PUNCT
aji-178	423	1	269	269	NUM
aji-178	423	2	-	-	SYM
aji-178	423	3	284	284	NUM
aji-178	423	4	,	,	PUNCT
aji-178	423	5	2025	2025	NUM
aji-178	423	6	;	;	PUNCT
aji-178	423	7	article	article	NOUN
aji-178	423	8	no.aji.147582	no.aji.147582	VERB
aji-178	423	9	281	281	NUM
aji-178	423	10	tuberculosis	tuberculosis	NOUN
aji-178	423	11	worldwide	worldwide	ADV
aji-178	423	12	:	:	PUNCT
aji-178	423	13	a	a	DET
aji-178	423	14	meta	meta	ADJ
aji-178	423	15	-	-	PUNCT
aji-178	423	16	analysis	analysis	NOUN
aji-178	423	17	and	and	CCONJ
aji-178	423	18	assessment	assessment	NOUN
aji-178	423	19	of	of	ADP
aji-178	423	20	cost	cost	NOUN
aji-178	423	21	-	-	PUNCT
aji-178	423	22	effectiveness	effectiveness	NOUN
aji-178	423	23	.	.	PUNCT
aji-178	424	1	the	the	DET
aji-178	424	2	lancet	lancet	PROPN
aji-178	424	3	,	,	PUNCT
aji-178	424	4	367(9517	367(9517	PROPN
aji-178	424	5	)	)	PUNCT
aji-178	424	6	,	,	PUNCT
aji-178	424	7	1173–1180	1173–1180	NUM
aji-178	424	8	.	.	PUNCT
aji-178	425	1	weinreich	weinreich	PROPN
aji-178	425	2	olsen	olsen	PROPN
aji-178	425	3	,	,	PUNCT
aji-178	425	4	a.	a.	PROPN
aji-178	425	5	,	,	PUNCT
aji-178	425	6	hansen	hansen	PROPN
aji-178	425	7	,	,	PUNCT
aji-178	425	8	p.	p.	PROPN
aji-178	425	9	r.	r.	PROPN
aji-178	425	10	,	,	PUNCT
aji-178	425	11	holm	holm	PROPN
aji-178	425	12	,	,	PUNCT
aji-178	425	13	a.	a.	PROPN
aji-178	425	14	,	,	PUNCT
aji-178	425	15	&	&	CCONJ
aji-178	425	16	andersen	andersen	PROPN
aji-178	425	17	,	,	PUNCT
aji-178	425	18	p.	p.	NOUN
aji-178	425	19	(	(	PUNCT
aji-178	425	20	2000	2000	NUM
aji-178	425	21	)	)	PUNCT
aji-178	425	22	.	.	PUNCT
aji-178	426	1	efficient	efficient	ADJ
aji-178	426	2	protection	protection	NOUN
aji-178	426	3	against	against	ADP
aji-178	426	4	mycobacterium	mycobacterium	NOUN
aji-178	426	5	tuberculosis	tuberculosis	NOUN
aji-178	426	6	by	by	ADP
aji-178	426	7	vaccination	vaccination	NOUN
aji-178	426	8	with	with	ADP
aji-178	426	9	a	a	DET
aji-178	426	10	single	single	ADJ
aji-178	426	11	subdominant	subdominant	ADJ
aji-178	426	12	epitope	epitope	NOUN
aji-178	426	13	from	from	ADP
aji-178	426	14	the	the	DET
aji-178	426	15	esat-6	esat-6	NUM
aji-178	426	16	antigen	antigen	NOUN
aji-178	426	17	.	.	PUNCT
aji-178	427	1	european	european	ADJ
aji-178	427	2	journal	journal	PROPN
aji-178	427	3	of	of	ADP
aji-178	427	4	immunology	immunology	NOUN
aji-178	427	5	,	,	PUNCT
aji-178	427	6	30(6	30(6	NUM
aji-178	427	7	)	)	PUNCT
aji-178	427	8	,	,	PUNCT
aji-178	427	9	1724–1732	1724–1732	NUM
aji-178	427	10	.	.	PUNCT
aji-178	427	11	wheeler	wheeler	NOUN
aji-178	427	12	,	,	PUNCT
aji-178	427	13	d.	d.	PROPN
aji-178	427	14	l.	l.	PROPN
aji-178	427	15	,	,	PUNCT
aji-178	427	16	barrett	barrett	PROPN
aji-178	427	17	,	,	PUNCT
aji-178	427	18	t.	t.	PROPN
aji-178	427	19	,	,	PUNCT
aji-178	427	20	benson	benson	PROPN
aji-178	427	21	,	,	PUNCT
aji-178	427	22	d.	d.	PROPN
aji-178	427	23	a.	a.	PROPN
aji-178	427	24	,	,	PUNCT
aji-178	427	25	bryant	bryant	PROPN
aji-178	427	26	,	,	PUNCT
aji-178	427	27	s.	s.	PROPN
aji-178	427	28	h.	h.	PROPN
aji-178	427	29	,	,	PUNCT
aji-178	427	30	canese	canese	PROPN
aji-178	427	31	,	,	PUNCT
aji-178	427	32	k.	k.	PROPN
aji-178	427	33	,	,	PUNCT
aji-178	427	34	chetvernin	chetvernin	ADJ
aji-178	427	35	,	,	PUNCT
aji-178	427	36	v.	v.	PROPN
aji-178	427	37	,	,	PUNCT
aji-178	427	38	church	church	NOUN
aji-178	427	39	,	,	PUNCT
aji-178	427	40	d.	d.	PROPN
aji-178	427	41	m.	m.	PROPN
aji-178	427	42	,	,	PUNCT
aji-178	427	43	et	et	PROPN
aji-178	427	44	al	al	PROPN
aji-178	427	45	.	.	PUNCT
aji-178	428	1	(	(	PUNCT
aji-178	428	2	2007	2007	NUM
aji-178	428	3	)	)	PUNCT
aji-178	428	4	.	.	PUNCT
aji-178	429	1	database	database	NOUN
aji-178	429	2	resources	resource	NOUN
aji-178	429	3	of	of	ADP
aji-178	429	4	the	the	DET
aji-178	429	5	national	national	ADJ
aji-178	429	6	center	center	NOUN
aji-178	429	7	for	for	ADP
aji-178	429	8	biotechnology	biotechnology	NOUN
aji-178	429	9	information	information	NOUN
aji-178	429	10	.	.	PUNCT
aji-178	430	1	nucleic	nucleic	ADJ
aji-178	430	2	acids	acid	NOUN
aji-178	430	3	research	research	NOUN
aji-178	430	4	,	,	PUNCT
aji-178	430	5	36(suppl	36(suppl	NUM
aji-178	430	6	.	.	NOUN
aji-178	430	7	1	1	NUM
aji-178	430	8	)	)	PUNCT
aji-178	430	9	,	,	PUNCT
aji-178	430	10	d13	d13	NOUN
aji-178	430	11	–	–	PUNCT
aji-178	430	12	d21	d21	NOUN
aji-178	430	13	.	.	PUNCT
aji-178	431	1	world	world	PROPN
aji-178	431	2	health	health	PROPN
aji-178	431	3	organization	organization	PROPN
aji-178	431	4	.	.	PUNCT
aji-178	432	1	(	(	PUNCT
aji-178	432	2	2018	2018	NUM
aji-178	432	3	)	)	PUNCT
aji-178	432	4	.	.	PUNCT
aji-178	433	1	bcg	bcg	PROPN
aji-178	433	2	vaccine	vaccine	NOUN
aji-178	433	3	:	:	PUNCT
aji-178	433	4	who	who	PRON
aji-178	433	5	position	position	VERB
aji-178	433	6	paper	paper	NOUN
aji-178	433	7	,	,	PUNCT
aji-178	433	8	february	february	PROPN
aji-178	433	9	2018	2018	NUM
aji-178	433	10	–	–	PUNCT
aji-178	433	11	recommendations	recommendation	NOUN
aji-178	433	12	.	.	PUNCT
aji-178	434	1	vaccine	vaccine	NOUN
aji-178	434	2	,	,	PUNCT
aji-178	434	3	36(24	36(24	NUM
aji-178	434	4	)	)	PUNCT
aji-178	434	5	,	,	PUNCT
aji-178	434	6	3408	3408	NUM
aji-178	434	7	–	–	PUNCT
aji-178	434	8	3410	3410	NUM
aji-178	434	9	.	.	PUNCT
aji-178	435	1	yun	yun	PROPN
aji-178	435	2	,	,	PUNCT
aji-178	435	3	j.-s	j.-s	PROPN
aji-178	435	4	.	.	PUNCT
aji-178	435	5	,	,	PUNCT
aji-178	435	6	kim	kim	PROPN
aji-178	435	7	,	,	PUNCT
aji-178	435	8	a.	a.	PROPN
aji-178	435	9	r.	r.	PROPN
aji-178	435	10	,	,	PUNCT
aji-178	435	11	kim	kim	PROPN
aji-178	435	12	,	,	PUNCT
aji-178	435	13	s.	s.	PROPN
aji-178	435	14	m.	m.	PROPN
aji-178	435	15	,	,	PUNCT
aji-178	435	16	shin	shin	PROPN
aji-178	435	17	,	,	PUNCT
aji-178	435	18	e.	e.	PROPN
aji-178	435	19	,	,	PUNCT
aji-178	435	20	ha	ha	INTJ
aji-178	435	21	,	,	PUNCT
aji-178	435	22	s.-j	s.-j	PROPN
aji-178	435	23	.	.	PROPN
aji-178	435	24	,	,	PUNCT
aji-178	435	25	kim	kim	PROPN
aji-178	435	26	,	,	PUNCT
aji-178	435	27	d.	d.	PROPN
aji-178	435	28	,	,	PUNCT
aji-178	435	29	&	&	CCONJ
aji-178	435	30	jeong	jeong	PROPN
aji-178	435	31	,	,	PUNCT
aji-178	435	32	h.-s	h.-s	PROPN
aji-178	435	33	.	.	PUNCT
aji-178	436	1	(	(	PUNCT
aji-178	436	2	2024	2024	NUM
aji-178	436	3	)	)	PUNCT
aji-178	436	4	.	.	PUNCT
aji-178	437	1	in	in	ADP
aji-178	437	2	silico	silico	NOUN
aji-178	437	3	analysis	analysis	NOUN
aji-178	437	4	for	for	ADP
aji-178	437	5	the	the	DET
aji-178	437	6	development	development	NOUN
aji-178	437	7	of	of	ADP
aji-178	437	8	multiepitope	multiepitope	NOUN
aji-178	437	9	vaccines	vaccine	NOUN
aji-178	437	10	against	against	ADP
aji-178	437	11	mycobacterium	mycobacterium	NOUN
aji-178	437	12	tuberculosis	tuberculosis	NOUN
aji-178	437	13	.	.	PUNCT
aji-178	438	1	frontiers	frontier	NOUN
aji-178	438	2	in	in	ADP
aji-178	438	3	immunology	immunology	NOUN
aji-178	438	4	,	,	PUNCT
aji-178	438	5	15	15	NUM
aji-178	438	6	,	,	PUNCT
aji-178	438	7	1474346	1474346	NUM
aji-178	438	8	.	.	PUNCT
aji-178	439	1	naseema	naseema	NOUN
aji-178	439	2	;	;	PUNCT
aji-178	439	3	asian	asian	PROPN
aji-178	439	4	j.	j.	PROPN
aji-178	439	5	immunol	immunol	PROPN
aji-178	439	6	.	.	PROPN
aji-178	439	7	,	,	PUNCT
aji-178	439	8	vol	vol	NOUN
aji-178	439	9	.	.	PROPN
aji-178	439	10	8	8	NUM
aji-178	439	11	,	,	PUNCT
aji-178	439	12	no	no	INTJ
aji-178	439	13	.	.	NOUN
aji-178	439	14	1	1	NUM
aji-178	439	15	,	,	PUNCT
aji-178	439	16	pp	pp	ADJ
aji-178	439	17	.	.	PUNCT
aji-178	440	1	269	269	NUM
aji-178	440	2	-	-	SYM
aji-178	440	3	284	284	NUM
aji-178	440	4	,	,	PUNCT
aji-178	440	5	2025	2025	NUM
aji-178	440	6	;	;	PUNCT
aji-178	440	7	article	article	NOUN
aji-178	440	8	no.aji.147582	no.aji.147582	VERB
aji-178	440	9	282	282	NUM
aji-178	440	10	supplementary	supplementary	ADJ
aji-178	440	11	table	table	NOUN
aji-178	440	12	vaccine	vaccine	NOUN
aji-178	440	13	sequence	sequence	NOUN
aji-178	440	14	:	:	PUNCT
aji-178	440	15	mknarttliaaaiagtlvtrspagianaddagldpnaaagpdavgfdpnlppapdaapvdtppapeda	mknarttliaaaiagtlvtrspagianaddagldpnaaagpdavgfdpnlppapdaapvdtppapeda	PROPN
aji-178	440	16	gfdpnlppplapdflsppaeeappvpvaysvnwdaiaqcesggnwsintgngyygglqftagtwra	gfdpnlppplapdflsppaeeappvpvaysvnwdaiaqcesggnwsintgngyygglqftagtwra	PROPN
aji-178	440	17	nggsgsaanasreeqirvaenvlrsqgirawpvcgrrgeaaakaglwgnggsggaggnakkagli	nggsgsaanasreeqirvaenvlrsqgirawpvcgrrgeaaakaglwgnggsggaggnakkagli	PROPN
aji-178	440	18	gnggaggaggpnkkgspittlyvkidggtpkkggmggsgggigagtttkknvpidpspdydasdeik	gnggaggaggpnkkgspittlyvkidggtpkkggmggsgggigagtttkknvpidpspdydasdeik	PROPN
aji-178	440	19	kggtggaagllgwgangkkrgavtgppspvaaqenkktvqrqagctndvtinpkkvvanvytvqr	kggtggaagllgwgangkkrgavtgppspvaaqenkktvqrqagctndvtinpkkvvanvytvqr	NOUN
aji-178	440	20	qagctnkkggvgttggaggngggakkgnsgtantgfgnagnvkktatgiwylqdrvivaekkisty	qagctnkkggvgttggaggngggakkgnsgtantgfgnagnvkktatgiwylqdrvivaekkisty	ADJ
aji-178	440	21	fsalladptttpkknagagntgffdagnyngpgpgyavaeaataqsvqqdgpgpggqeyqavsaq	fsalladptttpkknagagntgffdagnyngpgpgyavaeaataqsvqqdgpgpggqeyqavsaq	PROPN
aji-178	440	22	asafhgpgpggnsyavaeaataqsvgpgpgrkdirttrvtvapqygpgpgggnsyavaeaataqs	asafhgpgpggnsyavaeaataqsvgpgpgrkdirttrvtvapqygpgpgggnsyavaeaataqs	PROPN
aji-178	440	23	aaystqaktramaayfmligaafyaaysgysgglyyaayqaalamevyaaynfmligaafaayrtye	aaystqaktramaayfmligaafyaaysgysgglyyaayqaalamevyaaynfmligaafaayrtye	PROPN
aji-178	440	24	atmslaayaaaasttalaayyvntsttsm	atmslaayaaaasttalaayyvntsttsm	PROPN
aji-178	440	25	adjuvant	adjuvant	ADJ
aji-178	440	26	(	(	PUNCT
aji-178	440	27	rpfe	rpfe	X
aji-178	440	28	)	)	PUNCT
aji-178	441	1	=	=	NOUN
aji-178	441	2	1	1	NUM
aji-178	441	3	-	-	SYM
aji-178	441	4	172	172	NUM
aji-178	441	5	14	14	NUM
aji-178	441	6	b	b	NOUN
aji-178	441	7	-	-	PUNCT
aji-178	441	8	cell	cell	NOUN
aji-178	441	9	epitopes	epitope	NOUN
aji-178	441	10	=	=	NOUN
aji-178	441	11	178	178	NUM
aji-178	441	12	-	-	SYM
aji-178	441	13	250	250	NUM
aji-178	441	14	5	5	NUM
aji-178	441	15	mhc	mhc	PROPN
aji-178	441	16	ii	ii	PROPN
aji-178	441	17	(	(	PUNCT
aji-178	441	18	htl	htl	PROPN
aji-178	441	19	epitopes	epitope	VERB
aji-178	441	20	)	)	PUNCT
aji-178	441	21	=	=	SYM
aji-178	441	22	433	433	NUM
aji-178	441	23	-	-	NUM
aji-178	441	24	527	527	NUM
aji-178	441	25	5	5	NUM
aji-178	441	26	mhc	mhc	PROPN
aji-178	441	27	i	i	PRON
aji-178	441	28	(	(	PUNCT
aji-178	441	29	ctl	ctl	PROPN
aji-178	441	30	epitopes	epitope	NOUN
aji-178	441	31	)	)	PUNCT
aji-178	441	32	=	=	SYM
aji-178	441	33	530	530	NUM
aji-178	441	34	-	-	SYM
aji-178	441	35	587	587	NUM
aji-178	441	36	3	3	NUM
aji-178	441	37	mhc	mhc	PROPN
aji-178	441	38	i	i	PROPN
aji-178	441	39	(	(	PUNCT
aji-178	441	40	hla	hla	PROPN
aji-178	441	41	-	-	PUNCT
aji-178	441	42	c	c	NOUN
aji-178	441	43	epitopes	epitope	NOUN
aji-178	441	44	)	)	PUNCT
aji-178	441	45	=	=	SYM
aji-178	441	46	590	590	NUM
aji-178	441	47	-	-	SYM
aji-178	441	48	623	623	NUM
aji-178	441	49	linkers	linker	NOUN
aji-178	441	50	table	table	NOUN
aji-178	441	51	1	1	NUM
aji-178	441	52	.	.	PUNCT
aji-178	441	53	comprehensive	comprehensive	ADJ
aji-178	441	54	epitope	epitope	PROPN
aji-178	441	55	mapping	mapping	NOUN
aji-178	441	56	of	of	ADP
aji-178	441	57	mycobacterium	mycobacterium	NOUN
aji-178	441	58	tuberculosis	tuberculosis	NOUN
aji-178	441	59	antigens	antigen	NOUN
aji-178	441	60	for	for	ADP
aji-178	441	61	multiepitope	multiepitope	NOUN
aji-178	441	62	vaccine	vaccine	NOUN
aji-178	441	63	design	design	NOUN
aji-178	441	64	gene	gene	NOUN
aji-178	441	65	name	name	NOUN
aji-178	441	66	b	b	NOUN
aji-178	441	67	-	-	PUNCT
aji-178	441	68	cell	cell	NOUN
aji-178	441	69	epitope	epitope	NOUN
aji-178	441	70	ctl	ctl	PROPN
aji-178	441	71	epitope	epitope	PROPN
aji-178	441	72	hla	hla	PROPN
aji-178	441	73	-	-	PUNCT
aji-178	441	74	c	c	PROPN
aji-178	441	75	epitope	epitope	PROPN
aji-178	441	76	htl	htl	PROPN
aji-178	441	77	epitope	epitope	PROPN
aji-178	441	78	ppe	ppe	PROPN
aji-178	441	79	68	68	NUM
aji-178	441	80	stqaktram	stqaktram	NOUN
aji-178	441	81	(	(	PUNCT
aji-178	441	82	b7,b8,b62	b7,b8,b62	PROPN
aji-178	441	83	)	)	PUNCT
aji-178	441	84	qaalamevy	qaalamevy	NOUN
aji-178	441	85	(	(	PUNCT
aji-178	441	86	a1,a26,b58,b62	a1,a26,b58,b62	NUM
aji-178	441	87	)	)	PUNCT
aji-178	441	88	rv0310c	rv0310c	PROPN
aji-178	442	1	tatgiwylqdrvivae	tatgiwylqdrvivae	NOUN
aji-178	442	2	fmligaafy	fmligaafy	PROPN
aji-178	442	3	(	(	PUNCT
aji-178	442	4	a1,a3,a26,b62	a1,a3,a26,b62	PROPN
aji-178	442	5	)	)	PUNCT
aji-178	442	6	rtyeatmsl	rtyeatmsl	NOUN
aji-178	442	7	(	(	PUNCT
aji-178	442	8	hla	hla	NOUN
aji-178	442	9	-	-	PUNCT
aji-178	442	10	c*01:02	c*01:02	NUM
aji-178	442	11	hla	hla	PROPN
aji-178	442	12	-	-	PUNCT
aji-178	442	13	c*03:02	c*03:02	NOUN
aji-178	442	14	hla	hla	PROPN
aji-178	442	15	-	-	PUNCT
aji-178	442	16	c*03:03	c*03:03	NOUN
aji-178	442	17	hla	hla	NOUN
aji-178	442	18	-	-	PUNCT
aji-178	442	19	c*03:04	c*03:04	NOUN
aji-178	442	20	hla	hla	NOUN
aji-178	442	21	-	-	PUNCT
aji-178	442	22	c*04:01	c*04:01	NOUN
aji-178	442	23	hla	hla	PROPN
aji-178	442	24	-	-	PUNCT
aji-178	442	25	c*05:01	c*05:01	NOUN
aji-178	442	26	hla	hla	PROPN
aji-178	442	27	-	-	PUNCT
aji-178	442	28	c*07:01	c*07:01	NOUN
aji-178	442	29	hla	hla	PROPN
aji-178	442	30	-	-	PUNCT
aji-178	442	31	c*07:02	c*07:02	PROPN
aji-178	442	32	hla	hla	PROPN
aji-178	442	33	-	-	PUNCT
aji-178	442	34	c*07:04	c*07:04	NOUN
aji-178	442	35	hla	hla	NOUN
aji-178	442	36	-	-	PUNCT
aji-178	442	37	c*08:01	c*08:01	VERB
aji-178	442	38	hla	hla	PROPN
aji-178	442	39	-	-	PUNCT
aji-178	442	40	c*08:02	c*08:02	X
aji-178	442	41	hla	hla	NOUN
aji-178	442	42	-	-	PUNCT
aji-178	442	43	c*12:02	c*12:02	X
aji-178	442	44	hla	hla	PROPN
aji-178	442	45	-	-	PUNCT
aji-178	442	46	c*12:03	c*12:03	NOUN
aji-178	442	47	hla	hla	PROPN
aji-178	442	48	-	-	PUNCT
aji-178	442	49	c*15:02	c*15:02	VERB
aji-178	442	50	hla	hla	PROPN
aji-178	442	51	-	-	PUNCT
aji-178	442	52	c*16:01	c*16:01	VERB
aji-178	442	53	hla	hla	PROPN
aji-178	442	54	-	-	PUNCT
aji-178	442	55	c*17:01	c*17:01	VERB
aji-178	442	56	)	)	PUNCT
aji-178	442	57	nfmligaaf	nfmligaaf	NOUN
aji-178	442	58	(	(	PUNCT
aji-178	442	59	a24,b8,b62	a24,b8,b62	ADJ
aji-178	442	60	)	)	PUNCT
aji-178	442	61	pe_pgrs35	pe_pgrs35	PROPN
aji-178	442	62	aglignggaggaggpn	aglignggaggaggpn	NOUN
aji-178	442	63	sgysgglyy	sgysgglyy	NOUN
aji-178	442	64	(	(	PUNCT
aji-178	442	65	a3,a26,b58,b62	a3,a26,b58,b62	NOUN
aji-178	442	66	)	)	PUNCT
aji-178	442	67	gqeyqavsaqasafh	gqeyqavsaqasafh	NOUN
aji-178	442	68	(	(	PUNCT
aji-178	442	69	drb1_0101	drb1_0101	X
aji-178	442	70	drb1_0401	drb1_0401	VERB
aji-178	442	71	drb1_0405	drb1_0405	NOUN
aji-178	442	72	drb1_0701	drb1_0701	ADP
aji-178	442	73	drb1_0802	drb1_0802	NOUN
aji-178	442	74	drb1_0901	drb1_0901	NOUN
aji-178	442	75	drb1_1101	drb1_1101	PROPN
aji-178	442	76	drb3_0202	drb3_0202	PUNCT
aji-178	443	1	gspittlyvkidggtp	gspittlyvkidggtp	PROPN
aji-178	443	2	ggtggaagllgwgang	ggtggaagllgwgang	PROPN
aji-178	443	3	istyfsalladptttp	istyfsalladptttp	ADJ
aji-178	443	4	naseema	naseema	NOUN
aji-178	443	5	;	;	PUNCT
aji-178	443	6	asian	asian	ADJ
aji-178	443	7	j.	j.	PROPN
aji-178	443	8	immunol	immunol	PROPN
aji-178	443	9	.	.	PROPN
aji-178	443	10	,	,	PUNCT
aji-178	443	11	vol	vol	NOUN
aji-178	443	12	.	.	PROPN
aji-178	443	13	8	8	NUM
aji-178	443	14	,	,	PUNCT
aji-178	443	15	no	no	INTJ
aji-178	443	16	.	.	NOUN
aji-178	443	17	1	1	NUM
aji-178	443	18	,	,	PUNCT
aji-178	443	19	pp	pp	ADJ
aji-178	443	20	.	.	PUNCT
aji-178	444	1	269	269	NUM
aji-178	444	2	-	-	SYM
aji-178	444	3	284	284	NUM
aji-178	444	4	,	,	PUNCT
aji-178	444	5	2025	2025	NUM
aji-178	444	6	;	;	PUNCT
aji-178	444	7	article	article	NOUN
aji-178	444	8	no.aji.147582	no.aji.147582	VERB
aji-178	444	9	283	283	NUM
aji-178	444	10	gene	gene	NOUN
aji-178	444	11	name	name	NOUN
aji-178	444	12	b	b	NOUN
aji-178	444	13	-	-	PUNCT
aji-178	444	14	cell	cell	NOUN
aji-178	444	15	epitope	epitope	NOUN
aji-178	444	16	ctl	ctl	PROPN
aji-178	444	17	epitope	epitope	PROPN
aji-178	444	18	hla	hla	PROPN
aji-178	444	19	-	-	PUNCT
aji-178	444	20	c	c	PROPN
aji-178	444	21	epitope	epitope	PROPN
aji-178	444	22	htl	htl	PROPN
aji-178	444	23	epitope	epitope	PROPN
aji-178	444	24	hla	hla	PROPN
aji-178	444	25	-	-	PUNCT
aji-178	444	26	dqa10501dqb10301	dqa10501dqb10301	NOUN
aji-178	444	27	hla	hla	PROPN
aji-178	444	28	-	-	PUNCT
aji-178	444	29	dqa10301dqb10302	dqa10301dqb10302	NOUN
aji-178	444	30	hla	hla	PROPN
aji-178	444	31	-	-	PUNCT
aji-178	444	32	dqa10401dqb10402	dqa10401dqb10402	PROPN
aji-178	444	33	hla	hla	ADJ
aji-178	444	34	-	-	PUNCT
aji-178	444	35	dqa10102dqb10602	dqa10102dqb10602	NOUN
aji-178	444	36	hla	hla	PROPN
aji-178	444	37	-	-	PUNCT
aji-178	444	38	dpa10201dpb11401	dpa10201dpb11401	NOUN
aji-178	444	39	)	)	PUNCT
aji-178	444	40	pe_pgrs31	pe_pgrs31	PRON
aji-178	444	41	aglwgnggsggaggna	aglwgnggsggaggna	PROPN
aji-178	444	42	ggmggsgggigagttt	ggmggsgggigagttt	ADJ
aji-178	444	43	aaaasttal	aaaasttal	NOUN
aji-178	444	44	(	(	PUNCT
aji-178	444	45	hla	hla	NOUN
aji-178	444	46	-	-	PUNCT
aji-178	444	47	c*01:02	c*01:02	NUM
aji-178	444	48	hla	hla	PROPN
aji-178	444	49	-	-	PUNCT
aji-178	444	50	c*03:02	c*03:02	NOUN
aji-178	444	51	hla	hla	PROPN
aji-178	444	52	-	-	PUNCT
aji-178	444	53	c*03:03	c*03:03	NOUN
aji-178	444	54	hla	hla	NOUN
aji-178	444	55	-	-	PUNCT
aji-178	444	56	c*03:04	c*03:04	NOUN
aji-178	444	57	hla	hla	NOUN
aji-178	444	58	-	-	PUNCT
aji-178	444	59	c*05:01	c*05:01	NOUN
aji-178	444	60	hla	hla	ADJ
aji-178	444	61	-	-	PUNCT
aji-178	444	62	c*07:04	c*07:04	NOUN
aji-178	444	63	hla	hla	NOUN
aji-178	444	64	-	-	PUNCT
aji-178	444	65	c*08:01	c*08:01	VERB
aji-178	444	66	hla	hla	PROPN
aji-178	444	67	-	-	PUNCT
aji-178	444	68	c*08:02	c*08:02	X
aji-178	444	69	hla	hla	NOUN
aji-178	444	70	-	-	PUNCT
aji-178	444	71	c*12:02	c*12:02	X
aji-178	444	72	hla	hla	PROPN
aji-178	444	73	-	-	PUNCT
aji-178	444	74	c*15:02	c*15:02	VERB
aji-178	444	75	hla	hla	PROPN
aji-178	444	76	-	-	PUNCT
aji-178	444	77	c*16:01	c*16:01	VERB
aji-178	444	78	hla	hla	PROPN
aji-178	444	79	-	-	PUNCT
aji-178	444	80	c*17:01	c*17:01	VERB
aji-178	444	81	)	)	PUNCT
aji-178	444	82	yavaeaataqsvqqd	yavaeaataqsvqqd	NOUN
aji-178	444	83	(	(	PUNCT
aji-178	444	84	hla	hla	NOUN
aji-178	444	85	-	-	PUNCT
aji-178	444	86	dqa10501dqb10201	dqa10501dqb10201	NOUN
aji-178	444	87	hla	hla	NOUN
aji-178	444	88	-	-	PUNCT
aji-178	444	89	dqa10501dqb10301	dqa10501dqb10301	NOUN
aji-178	444	90	hla	hla	PROPN
aji-178	444	91	-	-	PUNCT
aji-178	444	92	dqa10301dqb10302	dqa10301dqb10302	NOUN
aji-178	444	93	hla	hla	PROPN
aji-178	444	94	-	-	PUNCT
aji-178	444	95	dqa10401dqb10402	dqa10401dqb10402	NOUN
aji-178	444	96	hla	hla	ADJ
aji-178	444	97	-	-	PUNCT
aji-178	444	98	dqa10102dqb10602	dqa10102dqb10602	NOUN
aji-178	444	99	)	)	PUNCT
aji-178	444	100	gnsyavaeaataqsv	gnsyavaeaataqsv	NOUN
aji-178	444	101	(	(	PUNCT
aji-178	444	102	drb1_0101	drb1_0101	X
aji-178	444	103	drb1_1101	drb1_1101	X
aji-178	444	104	drb3_0202	drb3_0202	X
aji-178	444	105	hla	hla	PROPN
aji-178	444	106	-	-	PUNCT
aji-178	444	107	dqa10501dqb10301	dqa10501dqb10301	PROPN
aji-178	444	108	hla	hla	PROPN
aji-178	444	109	-	-	PUNCT
aji-178	444	110	dpa10201dpb11401	dpa10201dpb11401	NOUN
aji-178	444	111	)	)	PUNCT
aji-178	444	112	ggvgttggaggnggga	ggvgttggaggnggga	NOUN
aji-178	444	113	ggnsyavaeaataqs	ggnsyavaeaataq	NOUN
aji-178	444	114	(	(	PUNCT
aji-178	444	115	drb1_0405	drb1_0405	VERB
aji-178	444	116	drb1_0701	drb1_0701	PRON
aji-178	444	117	drb1_0802	drb1_0802	NOUN
aji-178	444	118	drb1_0901	drb1_0901	ADJ
aji-178	444	119	hla	hla	NOUN
aji-178	444	120	-	-	PUNCT
aji-178	444	121	dqa10501dqb10201	dqa10501dqb10201	NOUN
aji-178	444	122	hla	hla	NOUN
aji-178	444	123	-	-	PUNCT
aji-178	444	124	dqa10301dqb10302	dqa10301dqb10302	NOUN
aji-178	444	125	hla	hla	NOUN
aji-178	444	126	-	-	PUNCT
aji-178	444	127	dqa10401dqb10402	dqa10401dqb10402	NOUN
aji-178	444	128	)	)	PUNCT
aji-178	444	129	lpqg	lpqg	NOUN
aji-178	444	130	rkdirttrvtvapqy	rkdirttrvtvapqy	NOUN
aji-178	444	131	(	(	PUNCT
aji-178	444	132	drb1_0401	drb1_0401	NOUN
aji-178	444	133	drb1_0701	drb1_0701	PRON
aji-178	444	134	drb1_0802	drb1_0802	NOUN
aji-178	444	135	drb4_0101	drb4_0101	ADJ
aji-178	444	136	hla	hla	PROPN
aji-178	444	137	-	-	PUNCT
aji-178	444	138	dqa10301dqb10302	dqa10301dqb10302	NOUN
aji-178	444	139	hla	hla	PROPN
aji-178	444	140	-	-	PUNCT
aji-178	444	141	dqa10401dqb10402	dqa10401dqb10402	PROPN
aji-178	444	142	hla	hla	ADJ
aji-178	444	143	-	-	PUNCT
aji-178	444	144	dqa10102dqb10602	dqa10102dqb10602	NOUN
aji-178	444	145	hla	hla	PROPN
aji-178	444	146	-	-	PUNCT
aji-178	444	147	dpa10201dpb11401	dpa10201dpb11401	NOUN
aji-178	444	148	)	)	PUNCT
aji-178	444	149	ppe39	ppe39	PROPN
aji-178	444	150	gnsgtantgfgnagnv	gnsgtantgfgnagnv	PROPN
aji-178	444	151	yvntsttsm	yvntsttsm	PROPN
aji-178	444	152	(	(	PUNCT
aji-178	444	153	hla	hla	PROPN
aji-178	444	154	-	-	PUNCT
aji-178	444	155	c*02:02	c*02:02	VERB
aji-178	444	156	hla	hla	PROPN
aji-178	444	157	-	-	PUNCT
aji-178	444	158	c*02:09	c*02:09	NOUN
aji-178	444	159	hla	hla	NOUN
aji-178	444	160	-	-	PUNCT
aji-178	444	161	c*03:02	c*03:02	X
aji-178	444	162	hla	hla	PROPN
aji-178	444	163	-	-	PUNCT
aji-178	444	164	c*03:03	c*03:03	NOUN
aji-178	444	165	hla	hla	NOUN
aji-178	444	166	-	-	PUNCT
aji-178	444	167	c*03:04	c*03:04	NOUN
aji-178	444	168	hla	hla	NOUN
aji-178	444	169	-	-	PUNCT
aji-178	444	170	c*08:02	c*08:02	X
aji-178	444	171	hla	hla	NOUN
aji-178	444	172	-	-	PUNCT
aji-178	444	173	c*12:02	c*12:02	X
aji-178	444	174	hla	hla	PROPN
aji-178	444	175	-	-	PUNCT
aji-178	444	176	c*12:03	c*12:03	NOUN
aji-178	444	177	nagagntgffdagnyn	nagagntgffdagnyn	PROPN
aji-178	444	178	naseema	naseema	NOUN
aji-178	444	179	;	;	PUNCT
aji-178	444	180	asian	asian	ADJ
aji-178	444	181	j.	j.	PROPN
aji-178	444	182	immunol	immunol	PROPN
aji-178	444	183	.	.	PROPN
aji-178	444	184	,	,	PUNCT
aji-178	444	185	vol	vol	NOUN
aji-178	444	186	.	.	PROPN
aji-178	444	187	8	8	NUM
aji-178	444	188	,	,	PUNCT
aji-178	444	189	no	no	INTJ
aji-178	444	190	.	.	NOUN
aji-178	444	191	1	1	NUM
aji-178	444	192	,	,	PUNCT
aji-178	444	193	pp	pp	ADJ
aji-178	444	194	.	.	PUNCT
aji-178	445	1	269	269	NUM
aji-178	445	2	-	-	SYM
aji-178	445	3	284	284	NUM
aji-178	445	4	,	,	PUNCT
aji-178	445	5	2025	2025	NUM
aji-178	445	6	;	;	PUNCT
aji-178	445	7	article	article	NOUN
aji-178	445	8	no.aji.147582	no.aji.147582	VERB
aji-178	445	9	284	284	NUM
aji-178	445	10	gene	gene	NOUN
aji-178	445	11	name	name	NOUN
aji-178	445	12	b	b	NOUN
aji-178	445	13	-	-	PUNCT
aji-178	445	14	cell	cell	NOUN
aji-178	445	15	epitope	epitope	NOUN
aji-178	445	16	ctl	ctl	PROPN
aji-178	445	17	epitope	epitope	PROPN
aji-178	445	18	hla	hla	PROPN
aji-178	445	19	-	-	PUNCT
aji-178	445	20	c	c	PROPN
aji-178	445	21	epitope	epitope	PROPN
aji-178	445	22	htl	htl	PROPN
aji-178	445	23	epitope	epitope	PROPN
aji-178	445	24	hla	hla	PROPN
aji-178	445	25	-	-	PUNCT
aji-178	445	26	c*15:02	c*15:02	VERB
aji-178	445	27	hla	hla	PROPN
aji-178	445	28	-	-	PUNCT
aji-178	445	29	c*16:01	c*16:01	VERB
aji-178	445	30	hla	hla	PROPN
aji-178	445	31	-	-	PUNCT
aji-178	445	32	c*17:01	c*17:01	VERB
aji-178	445	33	)	)	PUNCT
aji-178	445	34	rv1975	rv1975	PROPN
aji-178	445	35	nvpidpspdydasdei	nvpidpspdydasdei	NOUN
aji-178	445	36	rgavtgppspvaaqen	rgavtgppspvaaqen	VERB
aji-178	445	37	tvqrqagctndvtinp	tvqrqagctndvtinp	NOUN
aji-178	445	38	vvanvytvqrqagctn	vvanvytvqrqagctn	ADJ
aji-178	445	39	table	table	NOUN
aji-178	445	40	2	2	NUM
aji-178	445	41	.	.	PUNCT
aji-178	446	1	docking	docking	NOUN
aji-178	446	2	results	result	NOUN
aji-178	446	3	(	(	PUNCT
aji-178	446	4	pydock	pydock	NOUN
aji-178	446	5	)	)	PUNCT
aji-178	446	6	vaccine	vaccine	NOUN
aji-178	446	7	construct	construct	VERB
aji-178	446	8	with	with	ADP
aji-178	446	9	tlr4	tlr4	NOUN
aji-178	446	10	rmsd	rmsd	NOUN
aji-178	446	11	from	from	ADP
aji-178	446	12	the	the	DET
aji-178	446	13	overall	overall	ADJ
aji-178	446	14	lowest	low	ADJ
aji-178	446	15	-	-	PUNCT
aji-178	446	16	energy	energy	NOUN
aji-178	446	17	structure	structure	NOUN
aji-178	446	18	0.248	0.248	NUM
aji-178	446	19	van	van	PROPN
aji-178	446	20	der	der	NOUN
aji-178	446	21	waals	waal	NOUN
aji-178	446	22	energy	energy	VERB
aji-178	446	23	42.436	42.436	NUM
aji-178	446	24	electrostatic	electrostatic	ADJ
aji-178	446	25	energy	energy	NOUN
aji-178	446	26	-10.009	-10.009	PROPN
aji-178	446	27	desolvation	desolvation	PROPN
aji-178	446	28	energy	energy	NOUN
aji-178	446	29	-49.937	-49.937	PUNCT
aji-178	447	1	z	z	NOUN
aji-178	447	2	-	-	PUNCT
aji-178	447	3	score	score	NOUN
aji-178	447	4	-1.10	-1.10	NOUN
aji-178	447	5	table	table	NOUN
aji-178	447	6	3	3	NUM
aji-178	447	7	.	.	X
aji-178	447	8	vaccine	vaccine	NOUN
aji-178	447	9	construct	construct	VERB
aji-178	447	10	with	with	ADP
aji-178	447	11	mhc	mhc	PROPN
aji-178	447	12	i	i	PRON
aji-178	447	13	rmsd	rmsd	VERB
aji-178	447	14	from	from	ADP
aji-178	447	15	the	the	DET
aji-178	447	16	overall	overall	ADJ
aji-178	447	17	lowest	low	ADJ
aji-178	447	18	-	-	PUNCT
aji-178	447	19	energy	energy	NOUN
aji-178	447	20	structure	structure	NOUN
aji-178	447	21	0.248	0.248	NUM
aji-178	447	22	van	van	PROPN
aji-178	447	23	der	der	NOUN
aji-178	447	24	waals	waal	NOUN
aji-178	447	25	energy	energy	VERB
aji-178	447	26	81.423	81.423	NUM
aji-178	447	27	electrostatic	electrostatic	ADJ
aji-178	447	28	energy	energy	NOUN
aji-178	447	29	-19.16	-19.16	PROPN
aji-178	447	30	desolvation	desolvation	NOUN
aji-178	447	31	energy	energy	NOUN
aji-178	447	32	-32.681	-32.681	PROPN
aji-178	447	33	z	z	NOUN
aji-178	447	34	-	-	PUNCT
aji-178	447	35	score	score	VERB
aji-178	447	36	-2.89	-2.89	PRON
aji-178	447	37	disclaimer	disclaimer	NOUN
aji-178	447	38	/	/	SYM
aji-178	447	39	publisher	publisher	NOUN
aji-178	447	40	’s	’s	PART
aji-178	447	41	note	note	NOUN
aji-178	447	42	:	:	PUNCT
aji-178	447	43	the	the	DET
aji-178	447	44	statements	statement	NOUN
aji-178	447	45	,	,	PUNCT
aji-178	447	46	opinions	opinion	NOUN
aji-178	447	47	and	and	CCONJ
aji-178	447	48	data	datum	NOUN
aji-178	447	49	contained	contain	VERB
aji-178	447	50	in	in	ADP
aji-178	447	51	all	all	DET
aji-178	447	52	publications	publication	NOUN
aji-178	447	53	are	be	AUX
aji-178	447	54	solely	solely	ADV
aji-178	447	55	those	those	PRON
aji-178	447	56	of	of	ADP
aji-178	447	57	the	the	DET
aji-178	447	58	individual	individual	ADJ
aji-178	447	59	author(s	author(s	PROPN
aji-178	447	60	)	)	PUNCT
aji-178	447	61	and	and	CCONJ
aji-178	447	62	contributor(s	contributor(s	NOUN
aji-178	447	63	)	)	PUNCT
aji-178	447	64	and	and	CCONJ
aji-178	447	65	not	not	PART
aji-178	447	66	of	of	ADP
aji-178	447	67	the	the	DET
aji-178	447	68	publisher	publisher	NOUN
aji-178	447	69	and/or	and/or	CCONJ
aji-178	447	70	the	the	DET
aji-178	447	71	editor(s	editor(s	NOUN
aji-178	447	72	)	)	PUNCT
aji-178	447	73	.	.	PUNCT
aji-178	448	1	this	this	DET
aji-178	448	2	publisher	publisher	NOUN
aji-178	448	3	and/or	and/or	CCONJ
aji-178	448	4	the	the	DET
aji-178	448	5	editor(s	editor(s	NOUN
aji-178	448	6	)	)	PUNCT
aji-178	448	7	disclaim	disclaim	VERB
aji-178	448	8	responsibility	responsibility	NOUN
aji-178	448	9	for	for	ADP
aji-178	448	10	any	any	DET
aji-178	448	11	injury	injury	NOUN
aji-178	448	12	to	to	ADP
aji-178	448	13	people	people	NOUN
aji-178	448	14	or	or	CCONJ
aji-178	448	15	property	property	NOUN
aji-178	448	16	resulting	result	VERB
aji-178	448	17	from	from	ADP
aji-178	448	18	any	any	DET
aji-178	448	19	ideas	idea	NOUN
aji-178	448	20	,	,	PUNCT
aji-178	448	21	methods	method	NOUN
aji-178	448	22	,	,	PUNCT
aji-178	448	23	instructions	instruction	NOUN
aji-178	448	24	or	or	CCONJ
aji-178	448	25	products	product	NOUN
aji-178	448	26	referred	refer	VERB
aji-178	448	27	to	to	ADP
aji-178	448	28	in	in	ADP
aji-178	448	29	the	the	DET
aji-178	448	30	content	content	NOUN
aji-178	448	31	.	.	PUNCT
aji-178	449	1	_	_	PUNCT
aji-178	450	1	_	_	PUNCT
aji-178	451	1	_	_	PUNCT
aji-178	452	1	_	_	PUNCT
aji-178	453	1	_	_	PUNCT
aji-178	454	1	_	_	PUNCT
aji-178	455	1	_	_	PUNCT
aji-178	456	1	_	_	PUNCT
aji-178	457	1	_	_	PUNCT
aji-178	458	1	_	_	PUNCT
aji-178	459	1	_	_	PUNCT
aji-178	460	1	_	_	PUNCT
aji-178	461	1	_	_	PUNCT
aji-178	462	1	_	_	PUNCT
aji-178	463	1	_	_	PUNCT
aji-178	464	1	_	_	PUNCT
aji-178	465	1	_	_	PUNCT
aji-178	466	1	_	_	PUNCT
aji-178	467	1	_	_	PUNCT
aji-178	468	1	_	_	PUNCT
aji-178	469	1	_	_	PUNCT
aji-178	470	1	_	_	PUNCT
aji-178	471	1	_	_	PUNCT
aji-178	472	1	_	_	PUNCT
aji-178	473	1	_	_	PUNCT
aji-178	474	1	_	_	PUNCT
aji-178	475	1	_	_	PUNCT
aji-178	476	1	_	_	PUNCT
aji-178	477	1	_	_	PUNCT
aji-178	478	1	_	_	PUNCT
aji-178	479	1	_	_	PUNCT
aji-178	480	1	_	_	PUNCT
aji-178	481	1	_	_	PUNCT
aji-178	482	1	_	_	PUNCT
aji-178	483	1	_	_	PUNCT
aji-178	484	1	_	_	PUNCT
aji-178	485	1	_	_	PUNCT
aji-178	486	1	_	_	PUNCT
aji-178	487	1	_	_	PUNCT
aji-178	488	1	_	_	PUNCT
aji-178	489	1	_	_	PUNCT
aji-178	490	1	_	_	PUNCT
aji-178	491	1	_	_	PUNCT
aji-178	492	1	_	_	PUNCT
aji-178	493	1	_	_	PUNCT
aji-178	494	1	_	_	PUNCT
aji-178	495	1	_	_	PUNCT
aji-178	496	1	_	_	PUNCT
aji-178	497	1	_	_	PUNCT
aji-178	498	1	_	_	PUNCT
aji-178	499	1	_	_	PUNCT
aji-178	500	1	_	_	PUNCT
aji-178	501	1	_	_	PUNCT
aji-178	502	1	_	_	PUNCT
aji-178	503	1	_	_	PUNCT
aji-178	504	1	_	_	PUNCT
aji-178	505	1	_	_	PUNCT
aji-178	506	1	_	_	PUNCT
aji-178	507	1	_	_	PUNCT
aji-178	508	1	_	_	PUNCT
aji-178	509	1	_	_	PUNCT
aji-178	510	1	_	_	PUNCT
aji-178	511	1	_	_	PUNCT
aji-178	512	1	_	_	PUNCT
aji-178	513	1	_	_	PUNCT
aji-178	514	1	_	_	PUNCT
aji-178	515	1	_	_	PUNCT
aji-178	516	1	_	_	PUNCT
aji-178	517	1	_	_	PUNCT
aji-178	518	1	_	_	PUNCT
aji-178	519	1	_	_	PUNCT
aji-178	520	1	_	_	PUNCT
aji-178	521	1	_	_	PUNCT
aji-178	522	1	_	_	PUNCT
aji-178	523	1	_	_	PUNCT
aji-178	524	1	_	_	PUNCT
aji-178	525	1	_	_	PUNCT
aji-178	526	1	_	_	PUNCT
aji-178	527	1	_	_	PUNCT
aji-178	528	1	_	_	PUNCT
aji-178	529	1	_	_	PUNCT
aji-178	530	1	©	©	PRON
aji-178	530	2	copyright	copyright	NOUN
aji-178	530	3	(	(	PUNCT
aji-178	530	4	2025	2025	NUM
aji-178	530	5	):	):	PUNCT
aji-178	530	6	author(s	author(s	NOUN
aji-178	530	7	)	)	PUNCT
aji-178	530	8	.	.	PUNCT
aji-178	531	1	the	the	DET
aji-178	531	2	licensee	licensee	NOUN
aji-178	531	3	is	be	AUX
aji-178	531	4	the	the	DET
aji-178	531	5	journal	journal	PROPN
aji-178	531	6	publisher	publisher	NOUN
aji-178	531	7	.	.	PUNCT
aji-178	532	1	this	this	PRON
aji-178	532	2	is	be	AUX
aji-178	532	3	an	an	DET
aji-178	532	4	open	open	ADJ
aji-178	532	5	access	access	NOUN
aji-178	532	6	article	article	NOUN
aji-178	532	7	distributed	distribute	VERB
aji-178	532	8	under	under	ADP
aji-178	532	9	the	the	DET
aji-178	532	10	terms	term	NOUN
aji-178	532	11	of	of	ADP
aji-178	532	12	the	the	DET
aji-178	532	13	creative	creative	ADJ
aji-178	532	14	commons	common	NOUN
aji-178	532	15	attribution	attribution	NOUN
aji-178	532	16	license	license	NOUN
aji-178	532	17	(	(	PUNCT
aji-178	532	18	http://creativecommons.org/licenses/by/4.0	http://creativecommons.org/licenses/by/4.0	NOUN
aji-178	532	19	)	)	PUNCT
aji-178	532	20	,	,	PUNCT
aji-178	532	21	which	which	PRON
aji-178	532	22	permits	permit	VERB
aji-178	532	23	unrestricted	unrestricted	ADJ
aji-178	532	24	use	use	NOUN
aji-178	532	25	,	,	PUNCT
aji-178	532	26	distribution	distribution	NOUN
aji-178	532	27	,	,	PUNCT
aji-178	532	28	and	and	CCONJ
aji-178	532	29	reproduction	reproduction	NOUN
aji-178	532	30	in	in	ADP
aji-178	532	31	any	any	DET
aji-178	532	32	medium	medium	NOUN
aji-178	532	33	,	,	PUNCT
aji-178	532	34	provided	provide	VERB
aji-178	532	35	the	the	DET
aji-178	532	36	original	original	ADJ
aji-178	532	37	work	work	NOUN
aji-178	532	38	is	be	AUX
aji-178	532	39	properly	properly	ADV
aji-178	532	40	cited	cite	VERB
aji-178	532	41	.	.	PUNCT
aji-178	533	1	peer	peer	NOUN
aji-178	533	2	-	-	PUNCT
aji-178	533	3	review	review	NOUN
aji-178	533	4	history	history	NOUN
aji-178	533	5	:	:	PUNCT
aji-178	533	6	the	the	DET
aji-178	533	7	peer	peer	NOUN
aji-178	533	8	review	review	NOUN
aji-178	533	9	history	history	NOUN
aji-178	533	10	for	for	ADP
aji-178	533	11	this	this	DET
aji-178	533	12	paper	paper	NOUN
aji-178	533	13	can	can	AUX
aji-178	533	14	be	be	AUX
aji-178	533	15	accessed	access	VERB
aji-178	533	16	here	here	ADV
aji-178	533	17	:	:	PUNCT
aji-178	533	18	https://pr.sdiarticle5.com/review-history/147582	https://pr.sdiarticle5.com/review-history/147582	NOUN
aji-178	533	19	https://pr.sdiarticle5.com/review-history/147582	https://pr.sdiarticle5.com/review-history/147582	PUNCT