id	sid	tid	token	lemma	pos
aji-31	1	1	_	_	PUNCT
aji-31	2	1	_	_	PUNCT
aji-31	3	1	_	_	PUNCT
aji-31	4	1	_	_	PUNCT
aji-31	5	1	_	_	PUNCT
aji-31	6	1	_	_	PUNCT
aji-31	7	1	_	_	PUNCT
aji-31	8	1	_	_	PUNCT
aji-31	9	1	_	_	PUNCT
aji-31	10	1	_	_	PUNCT
aji-31	11	1	_	_	PUNCT
aji-31	12	1	_	_	PUNCT
aji-31	13	1	_	_	PUNCT
aji-31	14	1	_	_	PUNCT
aji-31	15	1	_	_	PUNCT
aji-31	16	1	_	_	PUNCT
aji-31	17	1	_	_	PUNCT
aji-31	18	1	_	_	PUNCT
aji-31	19	1	_	_	PUNCT
aji-31	20	1	_	_	PUNCT
aji-31	21	1	_	_	PUNCT
aji-31	22	1	_	_	PUNCT
aji-31	23	1	_	_	PUNCT
aji-31	24	1	_	_	PUNCT
aji-31	25	1	_	_	PUNCT
aji-31	26	1	_	_	PUNCT
aji-31	27	1	_	_	PUNCT
aji-31	28	1	_	_	PUNCT
aji-31	29	1	_	_	PUNCT
aji-31	30	1	_	_	PUNCT
aji-31	31	1	_	_	PUNCT
aji-31	32	1	_	_	PUNCT
aji-31	33	1	_	_	PUNCT
aji-31	34	1	_	_	PUNCT
aji-31	35	1	_	_	PUNCT
aji-31	36	1	_	_	PUNCT
aji-31	37	1	_	_	PUNCT
aji-31	38	1	_	_	PUNCT
aji-31	39	1	_	_	PUNCT
aji-31	40	1	_	_	PUNCT
aji-31	41	1	_	_	PUNCT
aji-31	42	1	_	_	PUNCT
aji-31	43	1	_	_	PUNCT
aji-31	44	1	_	_	PUNCT
aji-31	45	1	_	_	PUNCT
aji-31	46	1	_	_	PUNCT
aji-31	47	1	_	_	PUNCT
aji-31	48	1	_	_	PUNCT
aji-31	49	1	_	_	PUNCT
aji-31	50	1	_	_	PUNCT
aji-31	51	1	_	_	PUNCT
aji-31	52	1	_	_	PUNCT
aji-31	53	1	_	_	PUNCT
aji-31	54	1	_	_	PUNCT
aji-31	55	1	_	_	PUNCT
aji-31	56	1	_	_	PUNCT
aji-31	57	1	_	_	PUNCT
aji-31	58	1	_	_	PUNCT
aji-31	59	1	_	_	PUNCT
aji-31	60	1	_	_	PUNCT
aji-31	61	1	_	_	PUNCT
aji-31	62	1	_	_	PUNCT
aji-31	63	1	_	_	PUNCT
aji-31	64	1	_	_	PUNCT
aji-31	65	1	_	_	PUNCT
aji-31	66	1	_	_	PUNCT
aji-31	67	1	_	_	PUNCT
aji-31	68	1	_	_	PUNCT
aji-31	69	1	_	_	PUNCT
aji-31	70	1	_	_	PUNCT
aji-31	71	1	_	_	PUNCT
aji-31	72	1	_	_	PUNCT
aji-31	73	1	_	_	PUNCT
aji-31	74	1	_	_	PUNCT
aji-31	75	1	_	_	PUNCT
aji-31	76	1	_	_	PUNCT
aji-31	77	1	_	_	PUNCT
aji-31	78	1	_	_	PUNCT
aji-31	79	1	_	_	PUNCT
aji-31	80	1	_	_	PUNCT
aji-31	81	1	_	_	PUNCT
aji-31	82	1	_	_	PUNCT
aji-31	83	1	_	_	PUNCT
aji-31	84	1	_	_	PUNCT
aji-31	85	1	_	_	PUNCT
aji-31	86	1	_	_	PUNCT
aji-31	87	1	_	_	PUNCT
aji-31	88	1	_	_	PUNCT
aji-31	89	1	_	_	PUNCT
aji-31	90	1	_	_	PUNCT
aji-31	91	1	_	_	PUNCT
aji-31	92	1	_	_	PUNCT
aji-31	93	1	_	_	PUNCT
aji-31	94	1	_	_	PUNCT
aji-31	95	1	_	_	PUNCT
aji-31	96	1	_	_	PUNCT
aji-31	97	1	_	_	PUNCT
aji-31	98	1	_	_	PUNCT
aji-31	99	1	_	_	PUNCT
aji-31	100	1	_	_	PUNCT
aji-31	101	1	_	_	PUNCT
aji-31	102	1	*	*	PUNCT
aji-31	102	2	corresponding	correspond	VERB
aji-31	102	3	author	author	NOUN
aji-31	102	4	:	:	PUNCT
aji-31	102	5	e	e	NOUN
aji-31	102	6	-	-	NOUN
aji-31	102	7	mail	mail	NOUN
aji-31	102	8	:	:	PUNCT
aji-31	102	9	elmafary@gmail.com	elmafary@gmail.com	PROPN
aji-31	102	10	;	;	PUNCT
aji-31	102	11	asian	asian	ADJ
aji-31	102	12	journal	journal	NOUN
aji-31	102	13	of	of	ADP
aji-31	102	14	immunology	immunology	NOUN
aji-31	102	15	3(1	3(1	NUM
aji-31	102	16	):	):	PUNCT
aji-31	102	17	223	223	NUM
aji-31	102	18	-	-	SYM
aji-31	102	19	232	232	NUM
aji-31	102	20	,	,	PUNCT
aji-31	102	21	2020	2020	NUM
aji-31	102	22	;	;	PUNCT
aji-31	102	23	article	article	NOUN
aji-31	102	24	no.aji.57637	no.aji.57637	ADJ
aji-31	102	25	molecular	molecular	ADJ
aji-31	102	26	pathogenesis	pathogenesis	NOUN
aji-31	102	27	,	,	PUNCT
aji-31	102	28	clinical	clinical	ADJ
aji-31	102	29	efficacy	efficacy	NOUN
aji-31	102	30	and	and	CCONJ
aji-31	102	31	safety	safety	NOUN
aji-31	102	32	of	of	ADP
aji-31	102	33	therapeutics	therapeutic	NOUN
aji-31	102	34	used	use	VERB
aji-31	102	35	in	in	ADP
aji-31	102	36	the	the	DET
aji-31	102	37	treatment	treatment	NOUN
aji-31	102	38	of	of	ADP
aji-31	102	39	osteoarthritis	osteoarthritis	NOUN
aji-31	102	40	shaayau	shaayau	NOUN
aji-31	102	41	shehu1	shehu1	PROPN
aji-31	103	1	*	*	PROPN
aji-31	103	2	,	,	PUNCT
aji-31	103	3	abdulaziz	abdulaziz	PROPN
aji-31	103	4	umar	umar	PROPN
aji-31	103	5	kurya2	kurya2	PROPN
aji-31	103	6	,	,	PUNCT
aji-31	103	7	kamal	kamal	PROPN
aji-31	103	8	murtala	murtala	PROPN
aji-31	103	9	farouq3	farouq3	PROPN
aji-31	103	10	and	and	CCONJ
aji-31	103	11	abdulhakim	abdulhakim	PROPN
aji-31	103	12	umar	umar	PROPN
aji-31	103	13	toro2	toro2	PROPN
aji-31	103	14	1	1	NUM
aji-31	103	15	department	department	NOUN
aji-31	103	16	of	of	ADP
aji-31	103	17	biochemistry	biochemistry	NOUN
aji-31	103	18	,	,	PUNCT
aji-31	103	19	usmanu	usmanu	PROPN
aji-31	103	20	danfodiyo	danfodiyo	PROPN
aji-31	103	21	university	university	PROPN
aji-31	103	22	,	,	PUNCT
aji-31	103	23	sokoto	sokoto	PROPN
aji-31	103	24	,	,	PUNCT
aji-31	103	25	nigeria	nigeria	PROPN
aji-31	103	26	.	.	PUNCT
aji-31	104	1	2	2	NUM
aji-31	104	2	school	school	NOUN
aji-31	104	3	of	of	ADP
aji-31	104	4	life	life	NOUN
aji-31	104	5	and	and	CCONJ
aji-31	104	6	allied	ally	VERB
aji-31	104	7	health	health	NOUN
aji-31	104	8	sciences	sciences	PROPN
aji-31	104	9	,	,	PUNCT
aji-31	104	10	glocal	glocal	ADJ
aji-31	104	11	university	university	NOUN
aji-31	104	12	,	,	PUNCT
aji-31	104	13	saharanpur	saharanpur	NOUN
aji-31	104	14	,	,	PUNCT
aji-31	104	15	uttar	uttar	PROPN
aji-31	104	16	pradesh	pradesh	PROPN
aji-31	104	17	,	,	PUNCT
aji-31	104	18	india	india	PROPN
aji-31	104	19	.	.	PROPN
aji-31	104	20	3	3	NUM
aji-31	104	21	department	department	NOUN
aji-31	104	22	of	of	ADP
aji-31	104	23	genetic	genetic	ADJ
aji-31	104	24	engineering	engineering	NOUN
aji-31	104	25	,	,	PUNCT
aji-31	104	26	sharda	sharda	PROPN
aji-31	104	27	university	university	PROPN
aji-31	104	28	,	,	PUNCT
aji-31	104	29	greater	great	ADJ
aji-31	104	30	noida	noida	PROPN
aji-31	104	31	,	,	PUNCT
aji-31	104	32	uttar	uttar	PROPN
aji-31	104	33	pradesh	pradesh	PROPN
aji-31	104	34	,	,	PUNCT
aji-31	104	35	india	india	PROPN
aji-31	104	36	.	.	PUNCT
aji-31	105	1	authors	author	NOUN
aji-31	105	2	’	’	PART
aji-31	105	3	contributions	contribution	NOUN
aji-31	105	4	this	this	DET
aji-31	105	5	work	work	NOUN
aji-31	105	6	was	be	AUX
aji-31	105	7	carried	carry	VERB
aji-31	105	8	out	out	ADP
aji-31	105	9	in	in	ADP
aji-31	105	10	collaboration	collaboration	NOUN
aji-31	105	11	among	among	ADP
aji-31	105	12	all	all	DET
aji-31	105	13	authors	author	NOUN
aji-31	105	14	.	.	PUNCT
aji-31	106	1	author	author	NOUN
aji-31	106	2	ss	ss	PROPN
aji-31	106	3	designed	design	VERB
aji-31	106	4	and	and	CCONJ
aji-31	106	5	supervised	supervise	VERB
aji-31	106	6	the	the	DET
aji-31	106	7	study	study	NOUN
aji-31	106	8	,	,	PUNCT
aji-31	106	9	author	author	NOUN
aji-31	106	10	auk	auk	PROPN
aji-31	106	11	wrote	write	VERB
aji-31	106	12	the	the	DET
aji-31	106	13	first	first	ADJ
aji-31	106	14	draft	draft	NOUN
aji-31	106	15	of	of	ADP
aji-31	106	16	the	the	DET
aji-31	106	17	manuscript	manuscript	NOUN
aji-31	106	18	,	,	PUNCT
aji-31	106	19	outline	outline	VERB
aji-31	106	20	the	the	DET
aji-31	106	21	protocol	protocol	NOUN
aji-31	106	22	and	and	CCONJ
aji-31	106	23	performed	perform	VERB
aji-31	106	24	the	the	DET
aji-31	106	25	statistical	statistical	ADJ
aji-31	106	26	analysis	analysis	NOUN
aji-31	106	27	while	while	SCONJ
aji-31	106	28	authors	author	NOUN
aji-31	106	29	kmf	kmf	PROPN
aji-31	106	30	and	and	CCONJ
aji-31	106	31	aut	aut	PROPN
aji-31	106	32	managed	manage	VERB
aji-31	106	33	the	the	DET
aji-31	106	34	literature	literature	NOUN
aji-31	106	35	search	search	NOUN
aji-31	106	36	and	and	CCONJ
aji-31	106	37	analyses	analysis	NOUN
aji-31	106	38	of	of	ADP
aji-31	106	39	the	the	DET
aji-31	106	40	study	study	NOUN
aji-31	106	41	.	.	PUNCT
aji-31	107	1	all	all	DET
aji-31	107	2	authors	author	NOUN
aji-31	107	3	read	read	VERB
aji-31	107	4	and	and	CCONJ
aji-31	107	5	approved	approve	VERB
aji-31	107	6	the	the	DET
aji-31	107	7	final	final	ADJ
aji-31	107	8	manuscript	manuscript	NOUN
aji-31	107	9	.	.	PUNCT
aji-31	108	1	article	article	NOUN
aji-31	108	2	information	information	PROPN
aji-31	108	3	editor(s	editor(s	PROPN
aji-31	108	4	):	):	PUNCT
aji-31	108	5	(	(	PUNCT
aji-31	108	6	1	1	X
aji-31	108	7	)	)	PUNCT
aji-31	108	8	dr	dr	PROPN
aji-31	108	9	.	.	PROPN
aji-31	108	10	cynthia	cynthia	PROPN
aji-31	108	11	aracely	aracely	ADV
aji-31	108	12	alvizo	alvizo	VERB
aji-31	108	13	báez	báez	ADJ
aji-31	108	14	,	,	PUNCT
aji-31	108	15	autonomous	autonomous	ADJ
aji-31	108	16	university	university	PROPN
aji-31	108	17	of	of	ADP
aji-31	108	18	nuevo	nuevo	PROPN
aji-31	108	19	leon	leon	PROPN
aji-31	108	20	,	,	PUNCT
aji-31	108	21	mexico	mexico	PROPN
aji-31	108	22	.	.	PUNCT
aji-31	109	1	reviewers	reviewer	NOUN
aji-31	109	2	:	:	PUNCT
aji-31	109	3	(	(	PUNCT
aji-31	109	4	1	1	X
aji-31	109	5	)	)	PUNCT
aji-31	109	6	m.k	m.k	PROPN
aji-31	109	7	.	.	PUNCT
aji-31	109	8	jayalakshmi	jayalakshmi	PROPN
aji-31	109	9	,	,	PUNCT
aji-31	109	10	rajiv	rajiv	PROPN
aji-31	109	11	gandhi	gandhi	PROPN
aji-31	109	12	university	university	PROPN
aji-31	109	13	of	of	ADP
aji-31	109	14	health	health	PROPN
aji-31	109	15	science	science	PROPN
aji-31	109	16	,	,	PUNCT
aji-31	109	17	india	india	PROPN
aji-31	109	18	.	.	PUNCT
aji-31	110	1	(	(	PUNCT
aji-31	110	2	2	2	X
aji-31	110	3	)	)	PUNCT
aji-31	110	4	vanessa	vanessa	PROPN
aji-31	110	5	de	de	PROPN
aji-31	110	6	melo	melo	PROPN
aji-31	110	7	cavalcanti	cavalcanti	PROPN
aji-31	110	8	dantas	dantas	PROPN
aji-31	110	9	,	,	PUNCT
aji-31	110	10	instituto	instituto	PROPN
aji-31	110	11	de	de	PROPN
aji-31	110	12	pesquisa	pesquisa	PROPN
aji-31	110	13	aggeu	aggeu	PROPN
aji-31	110	14	magalhães	magalhães	PROPN
aji-31	110	15	,	,	PUNCT
aji-31	110	16	brazil	brazil	PROPN
aji-31	110	17	.	.	PUNCT
aji-31	111	1	(	(	PUNCT
aji-31	111	2	3	3	X
aji-31	111	3	)	)	PUNCT
aji-31	111	4	marcello	marcello	PROPN
aji-31	111	5	zaia	zaia	PROPN
aji-31	111	6	oliveira	oliveira	PROPN
aji-31	111	7	,	,	PUNCT
aji-31	111	8	federal	federal	ADJ
aji-31	111	9	university	university	PROPN
aji-31	111	10	of	of	ADP
aji-31	111	11	parana	parana	PROPN
aji-31	111	12	,	,	PUNCT
aji-31	111	13	brazil	brazil	PROPN
aji-31	111	14	.	.	PUNCT
aji-31	112	1	complete	complete	ADJ
aji-31	112	2	peer	peer	NOUN
aji-31	112	3	review	review	NOUN
aji-31	112	4	history	history	NOUN
aji-31	112	5	:	:	PUNCT
aji-31	112	6	http://www.sdiarticle4.com/review-history/57637	http://www.sdiarticle4.com/review-history/57637	PROPN
aji-31	112	7	received	receive	VERB
aji-31	112	8	01	01	NUM
aji-31	112	9	april	april	PROPN
aji-31	112	10	2020	2020	NUM
aji-31	112	11	accepted	accept	VERB
aji-31	112	12	07	07	NUM
aji-31	112	13	june	june	PROPN
aji-31	112	14	2020	2020	NUM
aji-31	112	15	published	publish	VERB
aji-31	112	16	20	20	NUM
aji-31	112	17	june	june	PROPN
aji-31	112	18	2020	2020	NUM
aji-31	112	19	abstract	abstract	ADJ
aji-31	112	20	osteoarthritis	osteoarthritis	NOUN
aji-31	112	21	(	(	PUNCT
aji-31	112	22	oa	oa	NOUN
aji-31	112	23	)	)	PUNCT
aji-31	112	24	also	also	ADV
aji-31	112	25	known	know	VERB
aji-31	112	26	as	as	ADP
aji-31	112	27	degenerative	degenerative	ADJ
aji-31	112	28	joint	joint	ADJ
aji-31	112	29	disease	disease	NOUN
aji-31	112	30	,	,	PUNCT
aji-31	112	31	is	be	AUX
aji-31	112	32	the	the	DET
aji-31	112	33	most	most	ADV
aji-31	112	34	common	common	ADJ
aji-31	112	35	form	form	NOUN
aji-31	112	36	of	of	ADP
aji-31	112	37	arthritis	arthritis	NOUN
aji-31	112	38	which	which	PRON
aji-31	112	39	affects	affect	VERB
aji-31	112	40	all	all	DET
aji-31	112	41	the	the	DET
aji-31	112	42	tissues	tissue	NOUN
aji-31	112	43	of	of	ADP
aji-31	112	44	the	the	DET
aji-31	112	45	joint	joint	NOUN
aji-31	112	46	,	,	PUNCT
aji-31	112	47	including	include	VERB
aji-31	112	48	the	the	DET
aji-31	112	49	cartilage	cartilage	NOUN
aji-31	112	50	,	,	PUNCT
aji-31	112	51	bone	bone	NOUN
aji-31	112	52	,	,	PUNCT
aji-31	112	53	ligaments	ligament	NOUN
aji-31	112	54	,	,	PUNCT
aji-31	112	55	and	and	CCONJ
aji-31	112	56	muscles	muscle	NOUN
aji-31	112	57	.	.	PUNCT
aji-31	113	1	it	it	PRON
aji-31	113	2	can	can	AUX
aji-31	113	3	develop	develop	VERB
aji-31	113	4	in	in	ADP
aji-31	113	5	any	any	DET
aji-31	113	6	number	number	NOUN
aji-31	113	7	of	of	ADP
aji-31	113	8	joints	joint	NOUN
aji-31	113	9	,	,	PUNCT
aji-31	113	10	but	but	CCONJ
aji-31	113	11	most	most	ADV
aji-31	113	12	commonly	commonly	ADV
aji-31	113	13	affects	affect	VERB
aji-31	113	14	the	the	DET
aji-31	113	15	knees	knee	NOUN
aji-31	113	16	,	,	PUNCT
aji-31	113	17	hands	hand	NOUN
aji-31	113	18	,	,	PUNCT
aji-31	113	19	and	and	CCONJ
aji-31	113	20	hips	hip	NOUN
aji-31	113	21	.	.	PUNCT
aji-31	114	1	oa	oa	PROPN
aji-31	114	2	is	be	AUX
aji-31	114	3	characterized	characterize	VERB
aji-31	114	4	by	by	ADP
aji-31	114	5	progressive	progressive	ADJ
aji-31	114	6	cartilage	cartilage	NOUN
aji-31	114	7	deterioration	deterioration	NOUN
aji-31	114	8	,	,	PUNCT
aji-31	114	9	subchondral	subchondral	ADJ
aji-31	114	10	bone	bone	NOUN
aji-31	114	11	remodeling	remodeling	NOUN
aji-31	114	12	,	,	PUNCT
aji-31	114	13	loss	loss	NOUN
aji-31	114	14	of	of	ADP
aji-31	114	15	joint	joint	ADJ
aji-31	114	16	space	space	NOUN
aji-31	114	17	,	,	PUNCT
aji-31	114	18	marginal	marginal	ADJ
aji-31	114	19	osteophytosis	osteophytosis	NOUN
aji-31	114	20	,	,	PUNCT
aji-31	114	21	and	and	CCONJ
aji-31	114	22	loss	loss	NOUN
aji-31	114	23	of	of	ADP
aji-31	114	24	joint	joint	ADJ
aji-31	114	25	function	function	NOUN
aji-31	114	26	.	.	PUNCT
aji-31	115	1	the	the	DET
aji-31	115	2	prevalence	prevalence	NOUN
aji-31	115	3	rate	rate	NOUN
aji-31	115	4	is	be	AUX
aji-31	115	5	estimated	estimate	VERB
aji-31	115	6	to	to	ADP
aji-31	115	7	about	about	ADP
aji-31	115	8	242	242	NUM
aji-31	115	9	million	million	NUM
aji-31	115	10	people	people	NOUN
aji-31	115	11	in	in	ADP
aji-31	115	12	the	the	DET
aji-31	115	13	world	world	NOUN
aji-31	115	14	.	.	PUNCT
aji-31	116	1	oa	oa	PROPN
aji-31	116	2	results	result	VERB
aji-31	116	3	from	from	ADP
aji-31	116	4	the	the	DET
aji-31	116	5	disruption	disruption	NOUN
aji-31	116	6	of	of	ADP
aji-31	116	7	the	the	DET
aji-31	116	8	balance	balance	NOUN
aji-31	116	9	between	between	ADP
aji-31	116	10	synthesis	synthesis	NOUN
aji-31	116	11	and	and	CCONJ
aji-31	116	12	degradation	degradation	NOUN
aji-31	116	13	of	of	ADP
aji-31	116	14	extracellular	extracellular	ADJ
aji-31	116	15	matrix	matrix	NOUN
aji-31	116	16	components	component	NOUN
aji-31	116	17	by	by	ADP
aji-31	116	18	the	the	DET
aji-31	116	19	chondrocyte	chondrocyte	NOUN
aji-31	116	20	in	in	ADP
aji-31	116	21	combination	combination	NOUN
aji-31	116	22	with	with	ADP
aji-31	116	23	increased	increase	VERB
aji-31	116	24	uncompensated	uncompensated	ADJ
aji-31	116	25	chondrocyte	chondrocyte	NOUN
aji-31	116	26	apoptosis	apoptosis	NOUN
aji-31	116	27	.	.	PUNCT
aji-31	117	1	it	it	PRON
aji-31	117	2	is	be	AUX
aji-31	117	3	increasingly	increasingly	ADV
aji-31	117	4	understood	understand	VERB
aji-31	117	5	that	that	SCONJ
aji-31	117	6	ageing	ageing	NOUN
aji-31	117	7	contributes	contribute	VERB
aji-31	117	8	to	to	ADP
aji-31	117	9	the	the	DET
aji-31	117	10	development	development	NOUN
aji-31	117	11	of	of	ADP
aji-31	117	12	osteoarthritis	osteoarthritis	NOUN
aji-31	117	13	by	by	ADP
aji-31	117	14	working	work	VERB
aji-31	117	15	in	in	ADP
aji-31	117	16	conjunction	conjunction	NOUN
aji-31	117	17	with	with	ADP
aji-31	117	18	a	a	DET
aji-31	117	19	variety	variety	NOUN
aji-31	117	20	of	of	ADP
aji-31	117	21	other	other	ADJ
aji-31	117	22	factors	factor	NOUN
aji-31	117	23	,	,	PUNCT
aji-31	117	24	both	both	CCONJ
aji-31	117	25	intrinsic	intrinsic	ADJ
aji-31	117	26	and	and	CCONJ
aji-31	117	27	extrinsic	extrinsic	ADJ
aji-31	117	28	to	to	ADP
aji-31	117	29	the	the	DET
aji-31	117	30	joint	joint	NOUN
aji-31	117	31	.	.	PUNCT
aji-31	118	1	several	several	ADJ
aji-31	118	2	abnormalities	abnormality	NOUN
aji-31	118	3	in	in	ADP
aji-31	118	4	components	component	NOUN
aji-31	118	5	of	of	ADP
aji-31	118	6	the	the	DET
aji-31	118	7	healthy	healthy	ADJ
aji-31	118	8	review	review	NOUN
aji-31	118	9	article	article	NOUN
aji-31	118	10	shehu	shehu	VERB
aji-31	118	11	et	et	PROPN
aji-31	118	12	al	al	PROPN
aji-31	118	13	.	.	PROPN
aji-31	118	14	;	;	PUNCT
aji-31	118	15	aji	aji	PROPN
aji-31	118	16	,	,	PUNCT
aji-31	118	17	3(1	3(1	NUM
aji-31	118	18	):	):	PUNCT
aji-31	118	19	223	223	NUM
aji-31	118	20	-	-	SYM
aji-31	118	21	232	232	NUM
aji-31	118	22	,	,	PUNCT
aji-31	118	23	2020	2020	NUM
aji-31	118	24	;	;	PUNCT
aji-31	118	25	article	article	NOUN
aji-31	118	26	no.aji.57637	no.aji.57637	ADV
aji-31	118	27	224	224	NUM
aji-31	118	28	joints	joint	NOUN
aji-31	118	29	such	such	ADJ
aji-31	118	30	as	as	ADP
aji-31	118	31	meniscus	meniscus	NOUN
aji-31	118	32	,	,	PUNCT
aji-31	118	33	articular	articular	ADJ
aji-31	118	34	cartilage	cartilage	NOUN
aji-31	118	35	,	,	PUNCT
aji-31	118	36	subchondral	subchondral	ADJ
aji-31	118	37	bone	bone	NOUN
aji-31	118	38	and	and	CCONJ
aji-31	118	39	synovial	synovial	ADJ
aji-31	118	40	membrane	membrane	NOUN
aji-31	118	41	results	result	NOUN
aji-31	118	42	to	to	ADP
aji-31	118	43	manifestation	manifestation	VERB
aji-31	118	44	the	the	DET
aji-31	118	45	disease	disease	NOUN
aji-31	118	46	.	.	PUNCT
aji-31	119	1	in	in	ADP
aji-31	119	2	an	an	DET
aji-31	119	3	attempt	attempt	NOUN
aji-31	119	4	to	to	PART
aji-31	119	5	discover	discover	VERB
aji-31	119	6	new	new	ADJ
aji-31	119	7	emerging	emerge	VERB
aji-31	119	8	therapeutic	therapeutic	ADJ
aji-31	119	9	target	target	NOUN
aji-31	119	10	,	,	PUNCT
aji-31	119	11	certain	certain	ADJ
aji-31	119	12	diagnostic	diagnostic	ADJ
aji-31	119	13	strategies	strategy	NOUN
aji-31	119	14	are	be	AUX
aji-31	119	15	applied	apply	VERB
aji-31	119	16	such	such	ADJ
aji-31	119	17	as	as	ADP
aji-31	119	18	x	x	NOUN
aji-31	119	19	-	-	NOUN
aji-31	119	20	ray	ray	NOUN
aji-31	119	21	,	,	PUNCT
aji-31	119	22	ultrasonography	ultrasonography	NOUN
aji-31	119	23	,	,	PUNCT
aji-31	119	24	anthroscopy	anthroscopy	NOUN
aji-31	119	25	and	and	CCONJ
aji-31	119	26	magnetic	magnetic	ADJ
aji-31	119	27	resonance	resonance	NOUN
aji-31	119	28	imaging	imaging	NOUN
aji-31	119	29	to	to	PART
aji-31	119	30	have	have	VERB
aji-31	119	31	a	a	DET
aji-31	119	32	deep	deep	ADJ
aji-31	119	33	insight	insight	NOUN
aji-31	119	34	on	on	ADP
aji-31	119	35	its	its	PRON
aji-31	119	36	effect	effect	NOUN
aji-31	119	37	and	and	CCONJ
aji-31	119	38	monitor	monitor	VERB
aji-31	119	39	the	the	DET
aji-31	119	40	progression	progression	NOUN
aji-31	119	41	of	of	ADP
aji-31	119	42	the	the	DET
aji-31	119	43	disease	disease	NOUN
aji-31	119	44	.	.	PUNCT
aji-31	120	1	interestingly	interestingly	ADV
aji-31	120	2	,	,	PUNCT
aji-31	120	3	many	many	ADJ
aji-31	120	4	clinical	clinical	ADJ
aji-31	120	5	researches	research	NOUN
aji-31	120	6	proved	prove	VERB
aji-31	120	7	efficacy	efficacy	NOUN
aji-31	120	8	of	of	ADP
aji-31	120	9	therapeutics	therapeutic	NOUN
aji-31	120	10	such	such	ADJ
aji-31	120	11	as	as	ADP
aji-31	120	12	adamulimab	adamulimab	NOUN
aji-31	120	13	which	which	PRON
aji-31	120	14	block	block	VERB
aji-31	120	15	tnf	tnf	PROPN
aji-31	120	16	-	-	PUNCT
aji-31	120	17	α	α	PROPN
aji-31	120	18	and	and	CCONJ
aji-31	120	19	plays	play	VERB
aji-31	120	20	significant	significant	ADJ
aji-31	120	21	role	role	NOUN
aji-31	120	22	in	in	ADP
aji-31	120	23	the	the	DET
aji-31	120	24	pathogenesis	pathogenesis	NOUN
aji-31	120	25	of	of	ADP
aji-31	120	26	the	the	DET
aji-31	120	27	disease	disease	NOUN
aji-31	120	28	,	,	PUNCT
aji-31	120	29	diacerein	diacerein	ADJ
aji-31	120	30	which	which	PRON
aji-31	120	31	inhibit	inhibit	VERB
aji-31	120	32	interleukin1	interleukin1	NOUN
aji-31	120	33	β	β	NOUN
aji-31	120	34	,	,	PUNCT
aji-31	120	35	natural	natural	ADJ
aji-31	120	36	anti	anti	ADJ
aji-31	120	37	-	-	ADJ
aji-31	120	38	inflammatory	inflammatory	ADJ
aji-31	120	39	compound	compound	NOUN
aji-31	120	40	such	such	ADJ
aji-31	120	41	as	as	ADP
aji-31	120	42	curcumin	curcumin	NOUN
aji-31	120	43	,	,	PUNCT
aji-31	120	44	bisphosphonate	bisphosphonate	VERB
aji-31	120	45	drugs	drug	NOUN
aji-31	120	46	such	such	ADJ
aji-31	120	47	as	as	ADP
aji-31	120	48	alendronate	alendronate	NOUN
aji-31	120	49	and	and	CCONJ
aji-31	120	50	risedronate	risedronate	NOUN
aji-31	120	51	and	and	CCONJ
aji-31	120	52	anti	anti	ADJ
aji-31	120	53	-	-	ADJ
aji-31	120	54	osteoporotic	osteoporotic	ADJ
aji-31	120	55	drugs	drug	NOUN
aji-31	120	56	such	such	ADJ
aji-31	120	57	as	as	ADP
aji-31	120	58	strontium	strontium	NOUN
aji-31	120	59	ranelate	ranelate	NOUN
aji-31	120	60	,	,	PUNCT
aji-31	120	61	chondroitin	chondroitin	NOUN
aji-31	120	62	sulfate	sulfate	NOUN
aji-31	120	63	,	,	PUNCT
aji-31	120	64	intraarticular	intraarticular	NOUN
aji-31	120	65	hyaluronic	hyaluronic	ADJ
aji-31	120	66	acids	acid	NOUN
aji-31	120	67	and	and	CCONJ
aji-31	120	68	glucosamine	glucosamine	NOUN
aji-31	120	69	sulfate	sulfate	NOUN
aji-31	120	70	are	be	AUX
aji-31	120	71	reported	report	VERB
aji-31	120	72	to	to	PART
aji-31	120	73	be	be	AUX
aji-31	120	74	effective	effective	ADJ
aji-31	120	75	and	and	CCONJ
aji-31	120	76	safe	safe	ADJ
aji-31	120	77	in	in	ADP
aji-31	120	78	the	the	DET
aji-31	120	79	management	management	NOUN
aji-31	120	80	of	of	ADP
aji-31	120	81	the	the	DET
aji-31	120	82	disease	disease	NOUN
aji-31	120	83	.	.	PUNCT
aji-31	121	1	keywords	keyword	NOUN
aji-31	121	2	:	:	PUNCT
aji-31	121	3	osteoarthritis	osteoarthritis	NOUN
aji-31	121	4	;	;	PUNCT
aji-31	121	5	degenerative	degenerative	ADJ
aji-31	121	6	joint	joint	ADJ
aji-31	121	7	disease	disease	NOUN
aji-31	121	8	;	;	PUNCT
aji-31	121	9	pathogenesis	pathogenesis	NOUN
aji-31	121	10	and	and	CCONJ
aji-31	121	11	therapeutics	therapeutic	NOUN
aji-31	121	12	.	.	PUNCT
aji-31	122	1	1	1	X
aji-31	122	2	.	.	X
aji-31	122	3	introduction	introduction	NOUN
aji-31	122	4	osteoarthritis	osteoarthritis	NOUN
aji-31	122	5	(	(	PUNCT
aji-31	122	6	oa	oa	NOUN
aji-31	122	7	)	)	PUNCT
aji-31	122	8	also	also	ADV
aji-31	122	9	known	know	VERB
aji-31	122	10	as	as	ADP
aji-31	122	11	degenerative	degenerative	ADJ
aji-31	122	12	joint	joint	ADJ
aji-31	122	13	disease	disease	NOUN
aji-31	122	14	is	be	AUX
aji-31	122	15	the	the	DET
aji-31	122	16	most	most	ADV
aji-31	122	17	common	common	ADJ
aji-31	122	18	form	form	NOUN
aji-31	122	19	of	of	ADP
aji-31	122	20	arthritis	arthritis	NOUN
aji-31	122	21	which	which	PRON
aji-31	122	22	affects	affect	VERB
aji-31	122	23	all	all	DET
aji-31	122	24	the	the	DET
aji-31	122	25	tissues	tissue	NOUN
aji-31	122	26	of	of	ADP
aji-31	122	27	the	the	DET
aji-31	122	28	joint	joint	NOUN
aji-31	122	29	,	,	PUNCT
aji-31	122	30	including	include	VERB
aji-31	122	31	the	the	DET
aji-31	122	32	cartilage	cartilage	NOUN
aji-31	122	33	,	,	PUNCT
aji-31	122	34	bone	bone	NOUN
aji-31	122	35	,	,	PUNCT
aji-31	122	36	ligaments	ligament	NOUN
aji-31	122	37	,	,	PUNCT
aji-31	122	38	and	and	CCONJ
aji-31	122	39	muscles	muscle	NOUN
aji-31	122	40	.	.	PUNCT
aji-31	123	1	it	it	PRON
aji-31	123	2	can	can	AUX
aji-31	123	3	develop	develop	VERB
aji-31	123	4	in	in	ADP
aji-31	123	5	any	any	DET
aji-31	123	6	number	number	NOUN
aji-31	123	7	of	of	ADP
aji-31	123	8	joints	joint	NOUN
aji-31	123	9	,	,	PUNCT
aji-31	123	10	but	but	CCONJ
aji-31	123	11	most	most	ADV
aji-31	123	12	commonly	commonly	ADV
aji-31	123	13	affects	affect	VERB
aji-31	123	14	the	the	DET
aji-31	123	15	knees	knee	NOUN
aji-31	123	16	,	,	PUNCT
aji-31	123	17	hands	hand	NOUN
aji-31	123	18	,	,	PUNCT
aji-31	123	19	and	and	CCONJ
aji-31	123	20	hips	hip	NOUN
aji-31	124	1	[	[	X
aji-31	124	2	1	1	NUM
aji-31	124	3	]	]	PUNCT
aji-31	124	4	.	.	PUNCT
aji-31	125	1	oa	oa	PROPN
aji-31	125	2	typically	typically	ADV
aji-31	125	3	occurs	occur	VERB
aji-31	125	4	later	later	ADV
aji-31	125	5	in	in	ADP
aji-31	125	6	life	life	NOUN
aji-31	125	7	,	,	PUNCT
aji-31	125	8	usually	usually	ADV
aji-31	125	9	after	after	ADP
aji-31	125	10	age	age	NOUN
aji-31	125	11	50	50	NUM
aji-31	125	12	,	,	PUNCT
aji-31	125	13	although	although	SCONJ
aji-31	125	14	may	may	AUX
aji-31	125	15	start	start	VERB
aji-31	125	16	earlier	early	ADV
aji-31	125	17	in	in	ADP
aji-31	125	18	the	the	DET
aji-31	125	19	case	case	NOUN
aji-31	125	20	of	of	ADP
aji-31	125	21	joint	joint	ADJ
aji-31	125	22	injury	injury	NOUN
aji-31	125	23	but	but	CCONJ
aji-31	125	24	symptoms	symptom	NOUN
aji-31	125	25	may	may	AUX
aji-31	125	26	vary	vary	VERB
aji-31	125	27	in	in	ADP
aji-31	125	28	severity	severity	NOUN
aji-31	125	29	,	,	PUNCT
aji-31	125	30	whereby	whereby	SCONJ
aji-31	125	31	oa	oa	VERB
aji-31	125	32	in	in	ADP
aji-31	125	33	its	its	PRON
aji-31	125	34	severe	severe	ADJ
aji-31	125	35	forms	form	NOUN
aji-31	125	36	restricts	restrict	VERB
aji-31	125	37	mobility	mobility	NOUN
aji-31	125	38	,	,	PUNCT
aji-31	125	39	interrupts	interrupt	VERB
aji-31	125	40	sleep	sleep	NOUN
aji-31	125	41	,	,	PUNCT
aji-31	125	42	and	and	CCONJ
aji-31	125	43	interferes	interfere	VERB
aji-31	125	44	with	with	ADP
aji-31	125	45	the	the	DET
aji-31	125	46	sufferer	sufferer	NOUN
aji-31	125	47	’s	’s	PART
aji-31	125	48	enjoyment	enjoyment	NOUN
aji-31	125	49	of	of	ADP
aji-31	125	50	life	life	NOUN
aji-31	125	51	[	[	X
aji-31	125	52	2	2	NUM
aji-31	125	53	]	]	PUNCT
aji-31	125	54	.	.	PUNCT
aji-31	126	1	the	the	DET
aji-31	126	2	disease	disease	NOUN
aji-31	126	3	has	have	VERB
aji-31	126	4	precisely	precisely	ADV
aji-31	126	5	no	no	DET
aji-31	126	6	cure	cure	NOUN
aji-31	126	7	.	.	PUNCT
aji-31	127	1	however	however	ADV
aji-31	127	2	,	,	PUNCT
aji-31	127	3	some	some	PRON
aji-31	127	4	of	of	ADP
aji-31	127	5	the	the	DET
aji-31	127	6	therapeutics	therapeutic	NOUN
aji-31	127	7	mainly	mainly	ADV
aji-31	127	8	aimed	aim	VERB
aji-31	127	9	at	at	ADP
aji-31	127	10	reducing	reduce	VERB
aji-31	127	11	the	the	DET
aji-31	127	12	pain	pain	NOUN
aji-31	127	13	,	,	PUNCT
aji-31	127	14	improving	improve	VERB
aji-31	127	15	the	the	DET
aji-31	127	16	joint	joint	ADJ
aji-31	127	17	function	function	NOUN
aji-31	127	18	,	,	PUNCT
aji-31	127	19	and	and	CCONJ
aji-31	127	20	in	in	ADP
aji-31	127	21	some	some	DET
aji-31	127	22	instances	instance	NOUN
aji-31	127	23	delay	delay	VERB
aji-31	127	24	the	the	DET
aji-31	127	25	progression	progression	NOUN
aji-31	127	26	of	of	ADP
aji-31	127	27	the	the	DET
aji-31	127	28	disease	disease	NOUN
aji-31	127	29	[	[	X
aji-31	127	30	3	3	NUM
aji-31	127	31	]	]	PUNCT
aji-31	127	32	.	.	PUNCT
aji-31	128	1	oa	oa	PROPN
aji-31	128	2	occurs	occur	VERB
aji-31	128	3	when	when	SCONJ
aji-31	128	4	the	the	DET
aji-31	128	5	protective	protective	ADJ
aji-31	128	6	cartilage	cartilage	NOUN
aji-31	128	7	that	that	PRON
aji-31	128	8	cushions	cushion	VERB
aji-31	128	9	the	the	DET
aji-31	128	10	ends	end	NOUN
aji-31	128	11	of	of	ADP
aji-31	128	12	two	two	NUM
aji-31	128	13	opposing	oppose	VERB
aji-31	128	14	bones	bone	NOUN
aji-31	128	15	wears	wear	VERB
aji-31	128	16	down	down	ADP
aji-31	128	17	over	over	ADP
aji-31	128	18	time	time	NOUN
aji-31	128	19	,	,	PUNCT
aji-31	128	20	although	although	SCONJ
aji-31	128	21	the	the	DET
aji-31	128	22	articular	articular	ADJ
aji-31	128	23	cartilage	cartilage	NOUN
aji-31	128	24	and	and	CCONJ
aji-31	128	25	subchondral	subchondral	ADJ
aji-31	128	26	bone	bone	NOUN
aji-31	128	27	often	often	ADV
aji-31	128	28	show	show	VERB
aji-31	128	29	the	the	DET
aji-31	128	30	most	most	ADV
aji-31	128	31	prominent	prominent	ADJ
aji-31	128	32	changes	change	NOUN
aji-31	128	33	[	[	X
aji-31	128	34	4	4	NUM
aji-31	128	35	]	]	PUNCT
aji-31	128	36	.	.	PUNCT
aji-31	129	1	oa	oa	PROPN
aji-31	129	2	is	be	AUX
aji-31	129	3	primarily	primarily	ADV
aji-31	129	4	characterized	characterize	VERB
aji-31	129	5	by	by	ADP
aji-31	129	6	progressive	progressive	ADJ
aji-31	129	7	cartilage	cartilage	NOUN
aji-31	129	8	deterioration	deterioration	NOUN
aji-31	129	9	,	,	PUNCT
aji-31	129	10	marginal	marginal	ADJ
aji-31	129	11	osteophytosis	osteophytosis	NOUN
aji-31	129	12	,	,	PUNCT
aji-31	129	13	subchondral	subchondral	ADJ
aji-31	129	14	bone	bone	NOUN
aji-31	129	15	remodeling	remodeling	NOUN
aji-31	129	16	,	,	PUNCT
aji-31	129	17	loss	loss	NOUN
aji-31	129	18	of	of	ADP
aji-31	129	19	joint	joint	ADJ
aji-31	129	20	space	space	NOUN
aji-31	129	21	,	,	PUNCT
aji-31	129	22	and	and	CCONJ
aji-31	129	23	ultimately	ultimately	ADV
aji-31	129	24	loss	loss	NOUN
aji-31	129	25	of	of	ADP
aji-31	129	26	joint	joint	ADJ
aji-31	129	27	function	function	NOUN
aji-31	129	28	[	[	X
aji-31	129	29	5	5	NUM
aji-31	129	30	]	]	PUNCT
aji-31	129	31	.	.	PUNCT
aji-31	130	1	oa	oa	PROPN
aji-31	130	2	is	be	AUX
aji-31	130	3	also	also	ADV
aji-31	130	4	characterized	characterize	VERB
aji-31	130	5	by	by	ADP
aji-31	130	6	a	a	DET
aji-31	130	7	degeneration	degeneration	NOUN
aji-31	130	8	of	of	ADP
aji-31	130	9	articular	articular	ADJ
aji-31	130	10	cartilage	cartilage	NOUN
aji-31	130	11	whereby	whereby	SCONJ
aji-31	130	12	the	the	DET
aji-31	130	13	breakdown	breakdown	NOUN
aji-31	130	14	leads	lead	VERB
aji-31	130	15	to	to	PART
aji-31	130	16	matrix	matrix	VERB
aji-31	130	17	fibrillation	fibrillation	NOUN
aji-31	130	18	,	,	PUNCT
aji-31	130	19	fissure	fissure	NOUN
aji-31	130	20	appearance	appearance	NOUN
aji-31	130	21	,	,	PUNCT
aji-31	130	22	gross	gross	ADJ
aji-31	130	23	ulceration	ulceration	NOUN
aji-31	130	24	,	,	PUNCT
aji-31	130	25	and	and	CCONJ
aji-31	130	26	full	full	ADJ
aji-31	130	27	thickness	thickness	NOUN
aji-31	130	28	loss	loss	NOUN
aji-31	130	29	of	of	ADP
aji-31	130	30	the	the	DET
aji-31	130	31	joint	joint	ADJ
aji-31	130	32	surface	surface	NOUN
aji-31	130	33	which	which	PRON
aji-31	130	34	is	be	AUX
aji-31	130	35	accompanied	accompany	VERB
aji-31	130	36	by	by	ADP
aji-31	130	37	hypertrophic	hypertrophic	ADJ
aji-31	130	38	changes	change	NOUN
aji-31	130	39	of	of	ADP
aji-31	130	40	bone	bone	NOUN
aji-31	130	41	with	with	ADP
aji-31	130	42	osteophyte	osteophyte	ADJ
aji-31	130	43	formation	formation	NOUN
aji-31	130	44	and	and	CCONJ
aji-31	130	45	subchondral	subchondral	ADJ
aji-31	130	46	bone	bone	NOUN
aji-31	130	47	plate	plate	NOUN
aji-31	130	48	thickening	thickening	NOUN
aji-31	130	49	.	.	PUNCT
aji-31	131	1	at	at	ADP
aji-31	131	2	the	the	DET
aji-31	131	3	early	early	ADJ
aji-31	131	4	stage	stage	NOUN
aji-31	131	5	of	of	ADP
aji-31	131	6	the	the	DET
aji-31	131	7	disease	disease	NOUN
aji-31	131	8	,	,	PUNCT
aji-31	131	9	there	there	PRON
aji-31	131	10	are	be	VERB
aji-31	131	11	changes	change	NOUN
aji-31	131	12	in	in	ADP
aji-31	131	13	the	the	DET
aji-31	131	14	synovial	synovial	ADJ
aji-31	131	15	membrane	membrane	NOUN
aji-31	131	16	together	together	ADV
aji-31	131	17	with	with	ADP
aji-31	131	18	an	an	DET
aji-31	131	19	inflammatory	inflammatory	ADJ
aji-31	131	20	reactions	reaction	NOUN
aji-31	131	21	while	while	SCONJ
aji-31	131	22	at	at	ADP
aji-31	131	23	advanced	advanced	ADJ
aji-31	131	24	stages	stage	NOUN
aji-31	131	25	,	,	PUNCT
aji-31	131	26	joint	joint	ADJ
aji-31	131	27	contractures	contracture	NOUN
aji-31	131	28	,	,	PUNCT
aji-31	131	29	muscles	muscle	NOUN
aji-31	131	30	atrophy	atrophy	NOUN
aji-31	131	31	and	and	CCONJ
aji-31	131	32	limb	limb	NOUN
aji-31	131	33	deformity	deformity	NOUN
aji-31	131	34	are	be	AUX
aji-31	131	35	commonly	commonly	ADV
aji-31	131	36	observed	observe	VERB
aji-31	131	37	[	[	X
aji-31	131	38	6	6	NUM
aji-31	131	39	]	]	PUNCT
aji-31	131	40	.	.	PUNCT
aji-31	132	1	2	2	X
aji-31	132	2	.	.	X
aji-31	132	3	materials	material	NOUN
aji-31	132	4	and	and	CCONJ
aji-31	132	5	methods	method	NOUN
aji-31	132	6	using	use	VERB
aji-31	132	7	online	online	ADJ
aji-31	132	8	databases	database	NOUN
aji-31	132	9	,	,	PUNCT
aji-31	132	10	we	we	PRON
aji-31	132	11	conducted	conduct	VERB
aji-31	132	12	a	a	DET
aji-31	132	13	literature	literature	NOUN
aji-31	132	14	review	review	NOUN
aji-31	132	15	of	of	ADP
aji-31	132	16	molecular	molecular	ADJ
aji-31	132	17	pathogenesis	pathogenesis	NOUN
aji-31	132	18	and	and	CCONJ
aji-31	132	19	novel	novel	ADJ
aji-31	132	20	therapeutic	therapeutic	ADJ
aji-31	132	21	potentials	potential	NOUN
aji-31	132	22	of	of	ADP
aji-31	132	23	osteoarthritis	osteoarthritis	NOUN
aji-31	132	24	.	.	PUNCT
aji-31	133	1	the	the	DET
aji-31	133	2	key	key	ADJ
aji-31	133	3	articles	article	NOUN
aji-31	133	4	used	use	VERB
aji-31	133	5	were	be	AUX
aji-31	133	6	retrieved	retrieve	VERB
aji-31	133	7	predominantly	predominantly	ADV
aji-31	133	8	from	from	ADP
aji-31	133	9	ncbi	ncbi	PROPN
aji-31	133	10	,	,	PUNCT
aji-31	133	11	google	google	PROPN
aji-31	133	12	scholar	scholar	NOUN
aji-31	133	13	,	,	PUNCT
aji-31	133	14	medline	medline	NOUN
aji-31	133	15	,	,	PUNCT
aji-31	133	16	uptodate	uptodate	ADJ
aji-31	133	17	,	,	PUNCT
aji-31	133	18	using	use	VERB
aji-31	133	19	the	the	DET
aji-31	133	20	terms	term	NOUN
aji-31	133	21	‘	'	PUNCT
aji-31	133	22	osteoarthritis	osteoarthritis	NOUN
aji-31	133	23	,	,	PUNCT
aji-31	133	24	degenerative	degenerative	ADJ
aji-31	133	25	joint	joint	ADJ
aji-31	133	26	disease	disease	NOUN
aji-31	133	27	,	,	PUNCT
aji-31	133	28	therapeutics	therapeutic	NOUN
aji-31	133	29	of	of	ADP
aji-31	133	30	osteoarthritis	osteoarthritis	NOUN
aji-31	133	31	as	as	ADP
aji-31	133	32	keywords	keyword	NOUN
aji-31	133	33	for	for	ADP
aji-31	133	34	our	our	PRON
aji-31	133	35	search	search	NOUN
aji-31	133	36	.	.	PUNCT
aji-31	134	1	we	we	PRON
aji-31	134	2	included	include	VERB
aji-31	134	3	scientific	scientific	ADJ
aji-31	134	4	publications	publication	NOUN
aji-31	134	5	from	from	ADP
aji-31	134	6	1	1	NUM
aji-31	134	7	st	st	PROPN
aji-31	134	8	january	january	PROPN
aji-31	134	9	2010	2010	NUM
aji-31	134	10	to	to	ADP
aji-31	134	11	15	15	NUM
aji-31	134	12	th	th	NUM
aji-31	134	13	december	december	PROPN
aji-31	134	14	2018	2018	NUM
aji-31	134	15	articles	article	NOUN
aji-31	134	16	focusing	focus	VERB
aji-31	134	17	on	on	ADP
aji-31	134	18	clinical	clinical	ADJ
aji-31	134	19	characteristics	characteristic	NOUN
aji-31	134	20	,	,	PUNCT
aji-31	134	21	epidemiology	epidemiology	NOUN
aji-31	134	22	,	,	PUNCT
aji-31	134	23	symptoms	symptom	NOUN
aji-31	134	24	,	,	PUNCT
aji-31	134	25	diagnosis	diagnosis	NOUN
aji-31	134	26	and	and	CCONJ
aji-31	134	27	treatments	treatment	NOUN
aji-31	134	28	for	for	ADP
aji-31	134	29	osteoarthritis	osteoarthritis	NOUN
aji-31	134	30	were	be	AUX
aji-31	134	31	eligible	eligible	ADJ
aji-31	134	32	for	for	ADP
aji-31	134	33	selection	selection	NOUN
aji-31	134	34	.	.	PUNCT
aji-31	135	1	3	3	X
aji-31	135	2	.	.	X
aji-31	135	3	epidemiology	epidemiology	NOUN
aji-31	135	4	of	of	ADP
aji-31	135	5	osteoarthritis	osteoarthritis	NOUN
aji-31	135	6	the	the	DET
aji-31	135	7	prevalence	prevalence	NOUN
aji-31	135	8	of	of	ADP
aji-31	135	9	oa	oa	PROPN
aji-31	135	10	is	be	AUX
aji-31	135	11	break	break	ADJ
aji-31	135	12	down	down	ADP
aji-31	135	13	based	base	VERB
aji-31	135	14	on	on	ADP
aji-31	135	15	different	different	ADJ
aji-31	135	16	demographic	demographic	ADJ
aji-31	135	17	criteria	criterion	NOUN
aji-31	135	18	.	.	PUNCT
aji-31	136	1	the	the	DET
aji-31	136	2	age	age	NOUN
aji-31	136	3	-	-	PUNCT
aji-31	136	4	related	relate	VERB
aji-31	136	5	demographics	demographic	NOUN
aji-31	136	6	shows	show	VERB
aji-31	136	7	that	that	SCONJ
aji-31	136	8	primary	primary	ADJ
aji-31	136	9	osteoarthritis	osteoarthritis	NOUN
aji-31	136	10	is	be	AUX
aji-31	136	11	mostly	mostly	ADV
aji-31	136	12	common	common	ADJ
aji-31	136	13	in	in	ADP
aji-31	136	14	elderly	elderly	ADJ
aji-31	136	15	and	and	CCONJ
aji-31	136	16	majority	majority	NOUN
aji-31	136	17	of	of	ADP
aji-31	136	18	the	the	DET
aji-31	136	19	patients	patient	NOUN
aji-31	136	20	are	be	AUX
aji-31	136	21	often	often	ADV
aji-31	136	22	asymptomatic	asymptomatic	ADJ
aji-31	136	23	.	.	PUNCT
aji-31	137	1	approximately	approximately	ADV
aji-31	137	2	80	80	NUM
aji-31	137	3	-	-	SYM
aji-31	137	4	90	90	NUM
aji-31	137	5	%	%	NOUN
aji-31	137	6	of	of	ADP
aji-31	137	7	individuals	individual	NOUN
aji-31	137	8	older	old	ADJ
aji-31	137	9	than	than	ADP
aji-31	137	10	65	65	NUM
aji-31	137	11	years	year	NOUN
aji-31	137	12	have	have	VERB
aji-31	137	13	evidence	evidence	NOUN
aji-31	137	14	of	of	ADP
aji-31	137	15	radiographic	radiographic	ADJ
aji-31	137	16	primary	primary	ADJ
aji-31	137	17	osteoarthritis	osteoarthritis	NOUN
aji-31	137	18	.	.	PUNCT
aji-31	138	1	however	however	ADV
aji-31	138	2	looking	look	VERB
aji-31	138	3	at	at	ADP
aji-31	138	4	the	the	DET
aji-31	138	5	gender	gender	NOUN
aji-31	138	6	variations	variation	NOUN
aji-31	138	7	women	woman	NOUN
aji-31	138	8	are	be	AUX
aji-31	138	9	at	at	ADP
aji-31	138	10	high	high	ADJ
aji-31	138	11	risk	risk	NOUN
aji-31	138	12	of	of	ADP
aji-31	138	13	the	the	DET
aji-31	138	14	infection	infection	NOUN
aji-31	138	15	than	than	ADP
aji-31	138	16	men	man	NOUN
aji-31	138	17	,	,	PUNCT
aji-31	138	18	this	this	PRON
aji-31	138	19	also	also	ADV
aji-31	138	20	varies	vary	VERB
aji-31	138	21	with	with	ADP
aji-31	138	22	age	age	NOUN
aji-31	138	23	where	where	SCONJ
aji-31	138	24	as	as	SCONJ
aji-31	138	25	women	woman	NOUN
aji-31	138	26	older	old	ADJ
aji-31	138	27	than	than	ADP
aji-31	138	28	55	55	NUM
aji-31	138	29	years	year	NOUN
aji-31	138	30	have	have	VERB
aji-31	138	31	high	high	ADJ
aji-31	138	32	prevalence	prevalence	NOUN
aji-31	138	33	rate	rate	NOUN
aji-31	138	34	.	.	PUNCT
aji-31	139	1	oa	oa	PROPN
aji-31	139	2	is	be	AUX
aji-31	139	3	a	a	DET
aji-31	139	4	major	major	ADJ
aji-31	139	5	cause	cause	NOUN
aji-31	139	6	of	of	ADP
aji-31	139	7	disability	disability	NOUN
aji-31	139	8	in	in	ADP
aji-31	139	9	older	old	ADJ
aji-31	139	10	adults	adult	NOUN
aji-31	139	11	worldwide	worldwide	ADV
aji-31	139	12	,	,	PUNCT
aji-31	139	13	according	accord	VERB
aji-31	139	14	to	to	ADP
aji-31	139	15	world	world	PROPN
aji-31	139	16	health	health	NOUN
aji-31	139	17	organization	organization	NOUN
aji-31	139	18	(	(	PUNCT
aji-31	139	19	who	who	PRON
aji-31	139	20	)	)	PUNCT
aji-31	139	21	9.6	9.6	NUM
aji-31	139	22	%	%	NOUN
aji-31	139	23	of	of	ADP
aji-31	139	24	men	man	NOUN
aji-31	139	25	and	and	CCONJ
aji-31	139	26	18.0	18.0	NUM
aji-31	139	27	%	%	NOUN
aji-31	139	28	of	of	ADP
aji-31	139	29	women	woman	NOUN
aji-31	139	30	aged	age	VERB
aji-31	139	31	60	60	NUM
aji-31	139	32	years	year	NOUN
aji-31	139	33	and	and	CCONJ
aji-31	139	34	above	above	ADV
aji-31	139	35	has	have	VERB
aji-31	139	36	symptomatic	symptomatic	ADJ
aji-31	139	37	osteoarthritis	osteoarthritis	NOUN
aji-31	139	38	worldwide	worldwide	ADV
aji-31	139	39	,	,	PUNCT
aji-31	139	40	this	this	DET
aji-31	139	41	lead	lead	NOUN
aji-31	139	42	to	to	ADP
aji-31	139	43	restriction	restriction	NOUN
aji-31	139	44	of	of	ADP
aji-31	139	45	movement	movement	NOUN
aji-31	139	46	in	in	ADP
aji-31	139	47	80	80	NUM
aji-31	139	48	%	%	NOUN
aji-31	139	49	of	of	ADP
aji-31	139	50	those	those	PRON
aji-31	139	51	with	with	ADP
aji-31	139	52	osteoarthritis	osteoarthritis	NOUN
aji-31	139	53	and	and	CCONJ
aji-31	139	54	incapable	incapable	ADJ
aji-31	139	55	of	of	ADP
aji-31	139	56	performing	perform	VERB
aji-31	139	57	major	major	ADJ
aji-31	139	58	daily	daily	ADJ
aji-31	139	59	activities	activity	NOUN
aji-31	139	60	of	of	ADP
aji-31	139	61	life	life	NOUN
aji-31	139	62	in	in	ADP
aji-31	139	63	20	20	NUM
aji-31	139	64	%	%	NOUN
aji-31	139	65	of	of	ADP
aji-31	139	66	oa	oa	PROPN
aji-31	139	67	patients	patient	NOUN
aji-31	139	68	[	[	X
aji-31	139	69	7	7	NUM
aji-31	139	70	]	]	PUNCT
aji-31	139	71	.	.	PUNCT
aji-31	140	1	in	in	ADP
aji-31	140	2	the	the	DET
aji-31	140	3	united	united	PROPN
aji-31	140	4	states	states	PROPN
aji-31	140	5	of	of	ADP
aji-31	140	6	america	america	PROPN
aji-31	140	7	,	,	PUNCT
aji-31	140	8	knee	knee	NOUN
aji-31	140	9	oa	oa	NOUN
aji-31	140	10	accounts	account	VERB
aji-31	140	11	for	for	ADP
aji-31	140	12	more	more	ADJ
aji-31	140	13	than	than	ADP
aji-31	140	14	80	80	NUM
aji-31	140	15	%	%	NOUN
aji-31	140	16	of	of	ADP
aji-31	140	17	the	the	DET
aji-31	140	18	disease	disease	NOUN
aji-31	140	19	’s	’s	PART
aji-31	140	20	total	total	ADJ
aji-31	140	21	burden	burden	NOUN
aji-31	140	22	and	and	CCONJ
aji-31	140	23	affects	affect	VERB
aji-31	140	24	at	at	ADV
aji-31	140	25	least	least	ADV
aji-31	140	26	19	19	NUM
aji-31	140	27	%	%	NOUN
aji-31	140	28	of	of	ADP
aji-31	140	29	shehu	shehu	NOUN
aji-31	140	30	et	et	PROPN
aji-31	140	31	al	al	PROPN
aji-31	140	32	.	.	PROPN
aji-31	140	33	;	;	PUNCT
aji-31	140	34	aji	aji	PROPN
aji-31	140	35	,	,	PUNCT
aji-31	140	36	3(1	3(1	NUM
aji-31	140	37	):	):	PUNCT
aji-31	140	38	223	223	NUM
aji-31	140	39	-	-	SYM
aji-31	140	40	232	232	NUM
aji-31	140	41	,	,	PUNCT
aji-31	140	42	2020	2020	NUM
aji-31	140	43	;	;	PUNCT
aji-31	140	44	article	article	NOUN
aji-31	140	45	no.aji.57637	no.aji.57637	ADJ
aji-31	140	46	225	225	NUM
aji-31	140	47	american	american	ADJ
aji-31	140	48	adults	adult	NOUN
aji-31	140	49	aged	age	VERB
aji-31	140	50	45	45	NUM
aji-31	140	51	years	year	NOUN
aji-31	140	52	and	and	CCONJ
aji-31	140	53	older	old	ADJ
aji-31	140	54	[	[	X
aji-31	140	55	8,9	8,9	NUM
aji-31	140	56	]	]	PUNCT
aji-31	140	57	.	.	PUNCT
aji-31	141	1	according	accord	VERB
aji-31	141	2	to	to	ADP
aji-31	141	3	data	datum	NOUN
aji-31	141	4	produced	produce	VERB
aji-31	141	5	by	by	ADP
aji-31	141	6	the	the	DET
aji-31	141	7	dutch	dutch	PROPN
aji-31	141	8	institute	institute	PROPN
aji-31	141	9	for	for	ADP
aji-31	141	10	public	public	ADJ
aji-31	141	11	health	health	NOUN
aji-31	141	12	,	,	PUNCT
aji-31	141	13	the	the	DET
aji-31	141	14	prevalence	prevalence	NOUN
aji-31	141	15	of	of	ADP
aji-31	141	16	knee	knee	NOUN
aji-31	141	17	oa	oa	X
aji-31	141	18	in	in	ADP
aji-31	141	19	individuals	individual	NOUN
aji-31	141	20	of	of	ADP
aji-31	141	21	55	55	NUM
aji-31	141	22	years	year	NOUN
aji-31	141	23	and	and	CCONJ
aji-31	141	24	above	above	ADV
aji-31	141	25	is	be	AUX
aji-31	141	26	reported	report	VERB
aji-31	141	27	as	as	ADP
aji-31	141	28	15.6	15.6	NUM
aji-31	141	29	%	%	NOUN
aji-31	141	30	in	in	ADP
aji-31	141	31	men	man	NOUN
aji-31	141	32	,	,	PUNCT
aji-31	141	33	30.5	30.5	NUM
aji-31	141	34	%	%	NOUN
aji-31	141	35	in	in	ADP
aji-31	141	36	women	woman	NOUN
aji-31	141	37	,	,	PUNCT
aji-31	141	38	and	and	CCONJ
aji-31	141	39	that	that	PRON
aji-31	141	40	of	of	ADP
aji-31	141	41	hips	hip	NOUN
aji-31	141	42	oa	oa	NOUN
aji-31	141	43	is	be	AUX
aji-31	141	44	4.4	4.4	NUM
aji-31	141	45	%	%	NOUN
aji-31	141	46	in	in	ADP
aji-31	141	47	men	man	NOUN
aji-31	141	48	and	and	CCONJ
aji-31	141	49	7.6	7.6	NUM
aji-31	141	50	%	%	NOUN
aji-31	141	51	in	in	ADP
aji-31	141	52	women	woman	NOUN
aji-31	141	53	[	[	X
aji-31	141	54	10	10	NUM
aji-31	141	55	]	]	PUNCT
aji-31	141	56	.	.	PUNCT
aji-31	142	1	recent	recent	ADJ
aji-31	142	2	study	study	NOUN
aji-31	142	3	of	of	ADP
aji-31	142	4	individual	individual	PROPN
aji-31	142	5	’s	’s	PART
aji-31	142	6	≥60	≥60	PROPN
aji-31	142	7	years	year	NOUN
aji-31	142	8	of	of	ADP
aji-31	142	9	age	age	NOUN
aji-31	142	10	living	live	VERB
aji-31	142	11	in	in	ADP
aji-31	142	12	spain	spain	PROPN
aji-31	142	13	documented	document	VERB
aji-31	142	14	a	a	DET
aji-31	142	15	prevalence	prevalence	NOUN
aji-31	142	16	of	of	ADP
aji-31	142	17	6.7	6.7	NUM
aji-31	142	18	%	%	NOUN
aji-31	142	19	in	in	ADP
aji-31	142	20	men	man	NOUN
aji-31	142	21	and	and	CCONJ
aji-31	142	22	8.0	8.0	NUM
aji-31	142	23	%	%	NOUN
aji-31	142	24	in	in	ADP
aji-31	142	25	women	woman	NOUN
aji-31	142	26	having	have	VERB
aji-31	142	27	oa	oa	PRON
aji-31	142	28	[	[	X
aji-31	142	29	9	9	NUM
aji-31	142	30	]	]	PUNCT
aji-31	142	31	.	.	PUNCT
aji-31	143	1	a	a	DET
aji-31	143	2	review	review	NOUN
aji-31	143	3	of	of	ADP
aji-31	143	4	several	several	ADJ
aji-31	143	5	investigations	investigation	NOUN
aji-31	143	6	in	in	ADP
aji-31	143	7	canada	canada	PROPN
aji-31	143	8	has	have	AUX
aji-31	143	9	reported	report	VERB
aji-31	143	10	the	the	DET
aji-31	143	11	overall	overall	ADJ
aji-31	143	12	prevalence	prevalence	NOUN
aji-31	143	13	ranges	range	VERB
aji-31	143	14	between	between	ADP
aji-31	143	15	7.5	7.5	NUM
aji-31	143	16	and	and	CCONJ
aji-31	143	17	14.7	14.7	NUM
aji-31	143	18	%	%	NOUN
aji-31	144	1	[	[	X
aji-31	144	2	11	11	NUM
aji-31	144	3	]	]	PUNCT
aji-31	144	4	.	.	PUNCT
aji-31	145	1	in	in	ADP
aji-31	145	2	addition	addition	NOUN
aji-31	145	3	,	,	PUNCT
aji-31	145	4	the	the	DET
aji-31	145	5	north	north	NOUN
aji-31	145	6	and	and	CCONJ
aji-31	145	7	east	east	NOUN
aji-31	145	8	regions	region	NOUN
aji-31	145	9	of	of	ADP
aji-31	145	10	china	china	PROPN
aji-31	145	11	had	have	VERB
aji-31	145	12	the	the	DET
aji-31	145	13	lowest	low	ADJ
aji-31	145	14	prevalence	prevalence	NOUN
aji-31	145	15	of	of	ADP
aji-31	145	16	symptomatic	symptomatic	ADJ
aji-31	145	17	knee	knee	NOUN
aji-31	145	18	oa	oa	VERB
aji-31	145	19	5.4	5.4	NUM
aji-31	145	20	%	%	NOUN
aji-31	145	21	and	and	CCONJ
aji-31	145	22	5.5	5.5	NUM
aji-31	145	23	%	%	NOUN
aji-31	145	24	,	,	PUNCT
aji-31	145	25	respectively	respectively	ADV
aji-31	145	26	,	,	PUNCT
aji-31	145	27	followed	follow	VERB
aji-31	145	28	by	by	ADP
aji-31	145	29	the	the	DET
aji-31	145	30	north	north	NOUN
aji-31	145	31	-	-	PUNCT
aji-31	145	32	east	east	NOUN
aji-31	145	33	7.0	7.0	NUM
aji-31	145	34	%	%	NOUN
aji-31	145	35	,	,	PUNCT
aji-31	145	36	south	south	ADJ
aji-31	145	37	-	-	PUNCT
aji-31	145	38	central	central	ADJ
aji-31	145	39	7.8	7.8	NUM
aji-31	145	40	%	%	NOUN
aji-31	145	41	,	,	PUNCT
aji-31	145	42	and	and	CCONJ
aji-31	145	43	north	north	NOUN
aji-31	145	44	-	-	PUNCT
aji-31	145	45	west	west	NOUN
aji-31	145	46	10.8	10.8	NUM
aji-31	145	47	%	%	NOUN
aji-31	145	48	regions	region	NOUN
aji-31	145	49	.	.	PUNCT
aji-31	146	1	surprisingly	surprisingly	ADV
aji-31	146	2	,	,	PUNCT
aji-31	146	3	the	the	DET
aji-31	146	4	prevalence	prevalence	NOUN
aji-31	146	5	was	be	AUX
aji-31	146	6	highest	high	ADJ
aji-31	146	7	13.7	13.7	NUM
aji-31	146	8	%	%	NOUN
aji-31	146	9	in	in	ADP
aji-31	146	10	subjects	subject	NOUN
aji-31	146	11	living	live	VERB
aji-31	146	12	in	in	ADP
aji-31	146	13	the	the	DET
aji-31	146	14	south	south	NOUN
aji-31	146	15	-	-	PUNCT
aji-31	146	16	west	west	NOUN
aji-31	146	17	region	region	NOUN
aji-31	147	1	[	[	X
aji-31	147	2	12	12	NUM
aji-31	147	3	]	]	PUNCT
aji-31	147	4	.	.	PUNCT
aji-31	148	1	furthermore	furthermore	ADV
aji-31	148	2	,	,	PUNCT
aji-31	148	3	prevalence	prevalence	NOUN
aji-31	148	4	of	of	ADP
aji-31	148	5	22	22	NUM
aji-31	148	6	%	%	NOUN
aji-31	148	7	to	to	PART
aji-31	148	8	39	39	NUM
aji-31	148	9	%	%	NOUN
aji-31	148	10	was	be	AUX
aji-31	148	11	reported	report	VERB
aji-31	148	12	in	in	ADP
aji-31	148	13	india	india	PROPN
aji-31	148	14	;	;	PUNCT
aji-31	148	15	however	however	ADV
aji-31	148	16	it	it	PRON
aji-31	148	17	is	be	AUX
aji-31	148	18	more	more	ADV
aji-31	148	19	common	common	ADJ
aji-31	148	20	in	in	ADP
aji-31	148	21	women	woman	NOUN
aji-31	148	22	than	than	ADP
aji-31	148	23	men	man	NOUN
aji-31	148	24	,	,	PUNCT
aji-31	148	25	whereby	whereby	SCONJ
aji-31	148	26	approximately	approximately	ADV
aji-31	148	27	45	45	NUM
aji-31	148	28	%	%	NOUN
aji-31	148	29	of	of	ADP
aji-31	148	30	women	woman	NOUN
aji-31	148	31	over	over	ADP
aji-31	148	32	the	the	DET
aji-31	148	33	age	age	NOUN
aji-31	148	34	of	of	ADP
aji-31	148	35	65	65	NUM
aji-31	148	36	years	year	NOUN
aji-31	148	37	have	have	VERB
aji-31	148	38	symptoms	symptom	NOUN
aji-31	148	39	while	while	SCONJ
aji-31	148	40	70	70	NUM
aji-31	148	41	%	%	NOUN
aji-31	148	42	of	of	ADP
aji-31	148	43	those	those	DET
aji-31	148	44	over	over	ADP
aji-31	148	45	65	65	NUM
aji-31	148	46	years	year	NOUN
aji-31	148	47	show	show	VERB
aji-31	148	48	radiological	radiological	ADJ
aji-31	148	49	evidence	evidence	NOUN
aji-31	148	50	of	of	ADP
aji-31	148	51	oa	oa	PRON
aji-31	149	1	[	[	X
aji-31	149	2	7	7	NUM
aji-31	149	3	]	]	PUNCT
aji-31	149	4	.	.	PUNCT
aji-31	150	1	fig	fig	NOUN
aji-31	150	2	.	.	PUNCT
aji-31	151	1	1	1	X
aji-31	151	2	.	.	X
aji-31	152	1	prevalence	prevalence	NOUN
aji-31	152	2	of	of	ADP
aji-31	152	3	oa	oa	PRON
aji-31	152	4	in	in	ADP
aji-31	152	5	the	the	DET
aji-31	152	6	united	united	PROPN
aji-31	152	7	states	states	PROPN
aji-31	152	8	of	of	ADP
aji-31	152	9	america	america	PROPN
aji-31	152	10	showing	show	VERB
aji-31	152	11	the	the	DET
aji-31	152	12	disease	disease	NOUN
aji-31	152	13	burden	burden	NOUN
aji-31	152	14	,	,	PUNCT
aji-31	152	15	adult	adult	NOUN
aji-31	152	16	infected	infect	VERB
aji-31	152	17	,	,	PUNCT
aji-31	152	18	men	man	NOUN
aji-31	152	19	and	and	CCONJ
aji-31	152	20	women	woman	NOUN
aji-31	152	21	[	[	X
aji-31	152	22	8,9	8,9	NUM
aji-31	152	23	]	]	X
aji-31	152	24	fig	fig	NOUN
aji-31	152	25	.	.	PUNCT
aji-31	153	1	2	2	X
aji-31	153	2	.	.	X
aji-31	153	3	shows	show	VERB
aji-31	153	4	spain	spain	PROPN
aji-31	153	5	and	and	CCONJ
aji-31	153	6	canada	canada	PROPN
aji-31	153	7	infection	infection	NOUN
aji-31	153	8	rate	rate	NOUN
aji-31	153	9	in	in	ADP
aji-31	153	10	men	man	NOUN
aji-31	153	11	and	and	CCONJ
aji-31	153	12	women	woman	NOUN
aji-31	153	13	[	[	X
aji-31	153	14	9,11	9,11	X
aji-31	153	15	]	]	X
aji-31	153	16	fig	fig	NOUN
aji-31	153	17	.	.	PUNCT
aji-31	154	1	3	3	X
aji-31	154	2	.	.	X
aji-31	154	3	shows	show	VERB
aji-31	154	4	overall	overall	ADJ
aji-31	154	5	prevalence	prevalence	NOUN
aji-31	154	6	rate	rate	NOUN
aji-31	154	7	for	for	ADP
aji-31	154	8	different	different	ADJ
aji-31	154	9	region	region	NOUN
aji-31	154	10	in	in	ADP
aji-31	154	11	china	china	PROPN
aji-31	154	12	regardless	regardless	ADV
aji-31	154	13	of	of	ADP
aji-31	154	14	gender	gender	NOUN
aji-31	154	15	variation	variation	NOUN
aji-31	154	16	[	[	X
aji-31	154	17	12	12	NUM
aji-31	154	18	]	]	SYM
aji-31	154	19	80	80	NUM
aji-31	154	20	%	%	NOUN
aji-31	154	21	19	19	NUM
aji-31	154	22	%	%	NOUN
aji-31	154	23	7.6	7.6	NUM
aji-31	154	24	%	%	NOUN
aji-31	154	25	4.4	4.4	NUM
aji-31	154	26	%	%	NOUN
aji-31	154	27	0	0	NUM
aji-31	154	28	20	20	NUM
aji-31	154	29	40	40	NUM
aji-31	154	30	60	60	NUM
aji-31	154	31	80	80	NUM
aji-31	154	32	100	100	NUM
aji-31	154	33	disease	disease	NOUN
aji-31	154	34	burden	burden	NOUN
aji-31	154	35	adults	adult	NOUN
aji-31	154	36	affected	affect	VERB
aji-31	154	37	women	woman	NOUN
aji-31	154	38	men	man	NOUN
aji-31	154	39	knee	knee	NOUN
aji-31	155	1	oa	oa	INTJ
aji-31	155	2	hip	hip	NOUN
aji-31	155	3	oa	oa	VERB
aji-31	155	4	6.7	6.7	NUM
aji-31	155	5	%	%	NOUN
aji-31	155	6	8	8	NUM
aji-31	155	7	%	%	NOUN
aji-31	155	8	7.5	7.5	NUM
aji-31	155	9	%	%	NOUN
aji-31	155	10	14.7	14.7	NUM
aji-31	155	11	%	%	NOUN
aji-31	155	12	0	0	NUM
aji-31	155	13	2	2	NUM
aji-31	155	14	4	4	NUM
aji-31	155	15	6	6	NUM
aji-31	155	16	8	8	NUM
aji-31	155	17	10	10	NUM
aji-31	155	18	12	12	NUM
aji-31	155	19	14	14	NUM
aji-31	155	20	16	16	NUM
aji-31	155	21	men	man	NOUN
aji-31	155	22	women	woman	NOUN
aji-31	155	23	men	man	NOUN
aji-31	155	24	women	women	PROPN
aji-31	155	25	spain	spain	PROPN
aji-31	155	26	canada	canada	PROPN
aji-31	156	1	5.4	5.4	NUM
aji-31	156	2	%	%	NOUN
aji-31	156	3	5.5	5.5	NUM
aji-31	156	4	%	%	NOUN
aji-31	156	5	7	7	NUM
aji-31	156	6	%	%	NOUN
aji-31	156	7	7.8	7.8	NUM
aji-31	156	8	%	%	NOUN
aji-31	156	9	10.8	10.8	NUM
aji-31	156	10	%	%	NOUN
aji-31	156	11	13.7	13.7	NUM
aji-31	156	12	%	%	NOUN
aji-31	156	13	0	0	NUM
aji-31	156	14	2	2	NUM
aji-31	156	15	4	4	NUM
aji-31	156	16	6	6	NUM
aji-31	156	17	8	8	NUM
aji-31	156	18	10	10	NUM
aji-31	156	19	12	12	NUM
aji-31	156	20	14	14	NUM
aji-31	156	21	16	16	NUM
aji-31	156	22	china	china	PROPN
aji-31	156	23	shehu	shehu	PROPN
aji-31	156	24	et	et	PROPN
aji-31	156	25	al	al	PROPN
aji-31	156	26	.	.	PROPN
aji-31	156	27	;	;	PUNCT
aji-31	156	28	aji	aji	PROPN
aji-31	156	29	,	,	PUNCT
aji-31	156	30	3(1	3(1	NUM
aji-31	156	31	):	):	PUNCT
aji-31	156	32	223	223	NUM
aji-31	156	33	-	-	SYM
aji-31	156	34	232	232	NUM
aji-31	156	35	,	,	PUNCT
aji-31	156	36	2020	2020	NUM
aji-31	156	37	;	;	PUNCT
aji-31	156	38	article	article	NOUN
aji-31	156	39	no.aji.57637	no.aji.57637	ADV
aji-31	156	40	226	226	NUM
aji-31	156	41	4	4	NUM
aji-31	156	42	.	.	PUNCT
aji-31	157	1	development	development	NOUN
aji-31	157	2	of	of	ADP
aji-31	157	3	osteoarthritis	osteoarthritis	NOUN
aji-31	157	4	there	there	PRON
aji-31	157	5	is	be	VERB
aji-31	157	6	strong	strong	ADJ
aji-31	157	7	correlation	correlation	NOUN
aji-31	157	8	between	between	ADP
aji-31	157	9	ageing	ageing	NOUN
aji-31	157	10	and	and	CCONJ
aji-31	157	11	development	development	NOUN
aji-31	157	12	of	of	ADP
aji-31	157	13	osteoarthritis	osteoarthritis	NOUN
aji-31	157	14	where	where	SCONJ
aji-31	157	15	it	it	PRON
aji-31	157	16	is	be	AUX
aji-31	157	17	increasingly	increasingly	ADV
aji-31	157	18	understood	understand	VERB
aji-31	157	19	that	that	SCONJ
aji-31	157	20	ageing	ageing	NOUN
aji-31	157	21	contributes	contribute	VERB
aji-31	157	22	to	to	ADP
aji-31	157	23	the	the	DET
aji-31	157	24	development	development	NOUN
aji-31	157	25	of	of	ADP
aji-31	157	26	osteoarthritis	osteoarthritis	NOUN
aji-31	157	27	by	by	ADP
aji-31	157	28	working	work	VERB
aji-31	157	29	in	in	ADP
aji-31	157	30	conjunction	conjunction	NOUN
aji-31	157	31	with	with	ADP
aji-31	157	32	a	a	DET
aji-31	157	33	variety	variety	NOUN
aji-31	157	34	of	of	ADP
aji-31	157	35	other	other	ADJ
aji-31	157	36	factors	factor	NOUN
aji-31	157	37	,	,	PUNCT
aji-31	157	38	both	both	CCONJ
aji-31	157	39	intrinsic	intrinsic	ADJ
aji-31	157	40	and	and	CCONJ
aji-31	157	41	extrinsic	extrinsic	ADJ
aji-31	157	42	to	to	ADP
aji-31	157	43	the	the	DET
aji-31	157	44	joint	joint	NOUN
aji-31	157	45	.	.	PUNCT
aji-31	158	1	it	it	PRON
aji-31	158	2	has	have	AUX
aji-31	158	3	become	become	VERB
aji-31	158	4	distinct	distinct	ADJ
aji-31	158	5	that	that	SCONJ
aji-31	158	6	changes	change	VERB
aji-31	158	7	that	that	PRON
aji-31	158	8	results	result	VERB
aji-31	158	9	due	due	ADJ
aji-31	158	10	to	to	ADP
aji-31	158	11	aging	age	VERB
aji-31	158	12	in	in	ADP
aji-31	158	13	the	the	DET
aji-31	158	14	musculoskeletal	musculoskeletal	ADJ
aji-31	158	15	system	system	NOUN
aji-31	158	16	contribute	contribute	VERB
aji-31	158	17	to	to	ADP
aji-31	158	18	the	the	DET
aji-31	158	19	development	development	NOUN
aji-31	158	20	of	of	ADP
aji-31	158	21	osteoarthritis	osteoarthritis	NOUN
aji-31	158	22	by	by	ADP
aji-31	158	23	working	work	VERB
aji-31	158	24	in	in	ADP
aji-31	158	25	conjunction	conjunction	NOUN
aji-31	158	26	with	with	ADP
aji-31	158	27	other	other	ADJ
aji-31	158	28	factors	factor	NOUN
aji-31	158	29	,	,	PUNCT
aji-31	158	30	both	both	PRON
aji-31	158	31	intrinsic	intrinsic	ADJ
aji-31	158	32	(	(	PUNCT
aji-31	158	33	e.g.	e.g.	ADJ
aji-31	158	34	,	,	PUNCT
aji-31	158	35	alignment	alignment	NOUN
aji-31	158	36	,	,	PUNCT
aji-31	158	37	overloading	overloading	NOUN
aji-31	158	38	)	)	PUNCT
aji-31	158	39	and	and	CCONJ
aji-31	158	40	extrinsic	extrinsic	ADJ
aji-31	158	41	(	(	PUNCT
aji-31	158	42	e.g.	e.g.	ADJ
aji-31	158	43	,	,	PUNCT
aji-31	158	44	genetics	genetic	NOUN
aji-31	158	45	)	)	PUNCT
aji-31	158	46	to	to	ADP
aji-31	158	47	the	the	DET
aji-31	158	48	joint	joint	NOUN
aji-31	158	49	[	[	X
aji-31	158	50	13	13	NUM
aji-31	158	51	]	]	PUNCT
aji-31	158	52	.	.	PUNCT
aji-31	159	1	the	the	DET
aji-31	159	2	primary	primary	ADJ
aji-31	159	3	changes	change	NOUN
aji-31	159	4	with	with	ADP
aji-31	159	5	osteoarthritis	osteoarthritis	NOUN
aji-31	159	6	occur	occur	VERB
aji-31	159	7	in	in	ADP
aji-31	159	8	the	the	DET
aji-31	159	9	articular	articular	ADJ
aji-31	159	10	cartilage	cartilage	NOUN
aji-31	159	11	,	,	PUNCT
aji-31	159	12	followed	follow	VERB
aji-31	159	13	by	by	ADP
aji-31	159	14	associated	associated	ADJ
aji-31	159	15	changes	change	NOUN
aji-31	159	16	in	in	ADP
aji-31	159	17	the	the	DET
aji-31	159	18	subchondral	subchondral	ADJ
aji-31	159	19	bone	bone	NOUN
aji-31	159	20	[	[	X
aji-31	159	21	14	14	NUM
aji-31	159	22	]	]	PUNCT
aji-31	159	23	.	.	PUNCT
aji-31	160	1	recently	recently	ADV
aji-31	160	2	,	,	PUNCT
aji-31	160	3	more	more	ADJ
aji-31	160	4	focus	focus	NOUN
aji-31	160	5	has	have	AUX
aji-31	160	6	been	be	AUX
aji-31	160	7	placed	place	VERB
aji-31	160	8	on	on	ADP
aji-31	160	9	the	the	DET
aji-31	160	10	subchondral	subchondral	ADJ
aji-31	160	11	bone	bone	NOUN
aji-31	160	12	as	as	ADP
aji-31	160	13	the	the	DET
aji-31	160	14	primary	primary	ADJ
aji-31	160	15	cause	cause	NOUN
aji-31	160	16	of	of	ADP
aji-31	160	17	symptomatic	symptomatic	ADJ
aji-31	160	18	disease	disease	NOUN
aji-31	160	19	.	.	PUNCT
aji-31	161	1	understanding	understanding	NOUN
aji-31	161	2	of	of	ADP
aji-31	161	3	changes	change	NOUN
aji-31	161	4	at	at	ADP
aji-31	161	5	early	early	ADJ
aji-31	161	6	stages	stage	NOUN
aji-31	161	7	that	that	PRON
aji-31	161	8	lead	lead	VERB
aji-31	161	9	to	to	ADP
aji-31	161	10	development	development	NOUN
aji-31	161	11	of	of	ADP
aji-31	161	12	osteoarthritis	osteoarthritis	NOUN
aji-31	161	13	is	be	AUX
aji-31	161	14	important	important	ADJ
aji-31	161	15	,	,	PUNCT
aji-31	161	16	since	since	SCONJ
aji-31	161	17	these	these	DET
aji-31	161	18	changes	change	NOUN
aji-31	161	19	could	could	AUX
aji-31	161	20	still	still	ADV
aji-31	161	21	be	be	AUX
aji-31	161	22	reversible	reversible	ADJ
aji-31	161	23	,	,	PUNCT
aji-31	161	24	and	and	CCONJ
aji-31	161	25	therefore	therefore	ADV
aji-31	161	26	,	,	PUNCT
aji-31	161	27	preventive	preventive	ADJ
aji-31	161	28	treatment	treatment	NOUN
aji-31	161	29	could	could	AUX
aji-31	161	30	be	be	AUX
aji-31	161	31	initiated	initiate	VERB
aji-31	161	32	to	to	PART
aji-31	161	33	halt	halt	VERB
aji-31	161	34	or	or	CCONJ
aji-31	161	35	reverse	reverse	VERB
aji-31	161	36	further	further	ADJ
aji-31	161	37	progression	progression	NOUN
aji-31	161	38	of	of	ADP
aji-31	161	39	the	the	DET
aji-31	161	40	disease	disease	NOUN
aji-31	161	41	.	.	PUNCT
aji-31	162	1	biomechanical	biomechanical	ADJ
aji-31	162	2	factors	factor	NOUN
aji-31	162	3	in	in	ADP
aji-31	162	4	oa	oa	NOUN
aji-31	162	5	play	play	VERB
aji-31	162	6	an	an	DET
aji-31	162	7	important	important	ADJ
aji-31	162	8	role	role	NOUN
aji-31	162	9	in	in	ADP
aji-31	162	10	the	the	DET
aji-31	162	11	health	health	NOUN
aji-31	162	12	of	of	ADP
aji-31	162	13	diarthrodial	diarthrodial	ADJ
aji-31	162	14	joints	joint	NOUN
aji-31	162	15	.	.	PUNCT
aji-31	163	1	altered	alter	VERB
aji-31	163	2	joint	joint	ADJ
aji-31	163	3	loading	loading	NOUN
aji-31	163	4	associated	associate	VERB
aji-31	163	5	to	to	ADP
aji-31	163	6	obesity	obesity	NOUN
aji-31	163	7	,	,	PUNCT
aji-31	163	8	malalignment	malalignment	NOUN
aji-31	163	9	,	,	PUNCT
aji-31	163	10	trauma	trauma	NOUN
aji-31	163	11	,	,	PUNCT
aji-31	163	12	or	or	CCONJ
aji-31	163	13	joint	joint	ADJ
aji-31	163	14	instability	instability	NOUN
aji-31	163	15	are	be	AUX
aji-31	163	16	most	most	ADV
aji-31	163	17	common	common	ADJ
aji-31	163	18	critical	critical	ADJ
aji-31	163	19	risk	risk	NOUN
aji-31	163	20	factor	factor	NOUN
aji-31	163	21	for	for	ADP
aji-31	163	22	joint	joint	ADJ
aji-31	163	23	degeneration	degeneration	NOUN
aji-31	163	24	[	[	X
aji-31	163	25	15	15	NUM
aji-31	163	26	]	]	PUNCT
aji-31	163	27	.	.	PUNCT
aji-31	164	1	fig	fig	NOUN
aji-31	164	2	.	.	PUNCT
aji-31	165	1	4	4	X
aji-31	165	2	.	.	X
aji-31	165	3	shows	show	VERB
aji-31	165	4	cartilage	cartilage	NOUN
aji-31	165	5	breakdown	breakdown	NOUN
aji-31	165	6	on	on	ADP
aji-31	165	7	healthy	healthy	ADJ
aji-31	165	8	joint	joint	NOUN
aji-31	165	9	which	which	PRON
aji-31	165	10	progresses	progress	VERB
aji-31	165	11	to	to	ADP
aji-31	165	12	several	several	ADJ
aji-31	165	13	stages	stage	NOUN
aji-31	165	14	of	of	ADP
aji-31	165	15	oa	oa	ADP
aji-31	165	16	development	development	NOUN
aji-31	165	17	;	;	PUNCT
aji-31	165	18	stage	stage	NOUN
aji-31	165	19	1	1	NUM
aji-31	165	20	involves	involve	VERB
aji-31	165	21	minimum	minimum	ADJ
aji-31	165	22	disruption	disruption	NOUN
aji-31	165	23	accompanied	accompany	VERB
aji-31	165	24	by	by	ADP
aji-31	165	25	10	10	NUM
aji-31	165	26	%	%	NOUN
aji-31	165	27	cartilage	cartilage	NOUN
aji-31	165	28	lost	lose	VERB
aji-31	165	29	,	,	PUNCT
aji-31	165	30	stage	stage	NOUN
aji-31	165	31	2	2	NUM
aji-31	165	32	involve	involve	VERB
aji-31	165	33	joint	joint	ADJ
aji-31	165	34	space	space	NOUN
aji-31	165	35	narrowing	narrow	VERB
aji-31	165	36	where	where	SCONJ
aji-31	165	37	cartilage	cartilage	NOUN
aji-31	165	38	breakdown	breakdown	NOUN
aji-31	165	39	begins	begin	VERB
aji-31	165	40	and	and	CCONJ
aji-31	165	41	characterized	characterize	VERB
aji-31	165	42	by	by	ADP
aji-31	165	43	osteophytes	osteophyte	NOUN
aji-31	165	44	formation	formation	NOUN
aji-31	165	45	,	,	PUNCT
aji-31	165	46	in	in	ADP
aji-31	165	47	stage	stage	NOUN
aji-31	165	48	3	3	NUM
aji-31	165	49	there	there	PRON
aji-31	165	50	is	be	VERB
aji-31	165	51	moderate	moderate	ADJ
aji-31	165	52	joint	joint	ADJ
aji-31	165	53	reduction	reduction	NOUN
aji-31	165	54	where	where	SCONJ
aji-31	165	55	gaps	gap	NOUN
aji-31	165	56	in	in	ADP
aji-31	165	57	the	the	DET
aji-31	165	58	cartilage	cartilage	NOUN
aji-31	165	59	expand	expand	VERB
aji-31	165	60	until	until	SCONJ
aji-31	165	61	they	they	PRON
aji-31	165	62	reach	reach	VERB
aji-31	165	63	bone	bone	NOUN
aji-31	165	64	and	and	CCONJ
aji-31	165	65	lastly	lastly	ADV
aji-31	165	66	stage	stage	VERB
aji-31	165	67	four	four	NUM
aji-31	165	68	which	which	PRON
aji-31	165	69	involves	involve	VERB
aji-31	165	70	60	60	NUM
aji-31	165	71	%	%	NOUN
aji-31	165	72	cartilage	cartilage	NOUN
aji-31	165	73	lost	lose	VERB
aji-31	165	74	and	and	CCONJ
aji-31	165	75	is	be	AUX
aji-31	165	76	characterized	characterize	VERB
aji-31	165	77	by	by	ADP
aji-31	165	78	large	large	ADJ
aji-31	165	79	osteophytes	osteophyte	NOUN
aji-31	165	80	[	[	X
aji-31	165	81	16,17	16,17	NUM
aji-31	165	82	]	]	PUNCT
aji-31	165	83	shehu	shehu	NOUN
aji-31	165	84	et	et	PROPN
aji-31	165	85	al	al	PROPN
aji-31	165	86	.	.	PROPN
aji-31	165	87	;	;	PUNCT
aji-31	165	88	aji	aji	PROPN
aji-31	165	89	,	,	PUNCT
aji-31	165	90	3(1	3(1	NUM
aji-31	165	91	):	):	PUNCT
aji-31	165	92	223	223	NUM
aji-31	165	93	-	-	SYM
aji-31	165	94	232	232	NUM
aji-31	165	95	,	,	PUNCT
aji-31	165	96	2020	2020	NUM
aji-31	165	97	;	;	PUNCT
aji-31	165	98	article	article	NOUN
aji-31	165	99	no.aji.57637	no.aji.57637	ADV
aji-31	165	100	227	227	NUM
aji-31	165	101	5	5	NUM
aji-31	165	102	.	.	PUNCT
aji-31	166	1	pathogenesis	pathogenesis	NOUN
aji-31	166	2	of	of	ADP
aji-31	166	3	osteoarthritis	osteoarthritis	NOUN
aji-31	166	4	oa	oa	PROPN
aji-31	166	5	results	result	VERB
aji-31	166	6	from	from	ADP
aji-31	166	7	the	the	DET
aji-31	166	8	disruption	disruption	NOUN
aji-31	166	9	of	of	ADP
aji-31	166	10	the	the	DET
aji-31	166	11	balance	balance	NOUN
aji-31	166	12	between	between	ADP
aji-31	166	13	synthesis	synthesis	NOUN
aji-31	166	14	and	and	CCONJ
aji-31	166	15	breakdown	breakdown	NOUN
aji-31	166	16	of	of	ADP
aji-31	166	17	extracellular	extracellular	ADJ
aji-31	166	18	matrix	matrix	NOUN
aji-31	166	19	components	component	NOUN
aji-31	166	20	by	by	ADP
aji-31	166	21	the	the	DET
aji-31	166	22	chondrocyte	chondrocyte	NOUN
aji-31	166	23	in	in	ADP
aji-31	166	24	addition	addition	NOUN
aji-31	166	25	with	with	ADP
aji-31	166	26	increased	increase	VERB
aji-31	166	27	uncompensated	uncompensated	ADJ
aji-31	166	28	chondrocyte	chondrocyte	NOUN
aji-31	166	29	apoptosis	apoptosis	NOUN
aji-31	166	30	[	[	X
aji-31	166	31	18	18	NUM
aji-31	166	32	]	]	PUNCT
aji-31	166	33	.	.	PUNCT
aji-31	167	1	in	in	ADP
aji-31	167	2	the	the	DET
aji-31	167	3	young	young	ADJ
aji-31	167	4	patient	patient	NOUN
aji-31	167	5	,	,	PUNCT
aji-31	167	6	the	the	DET
aji-31	167	7	pathogenesis	pathogenesis	NOUN
aji-31	167	8	of	of	ADP
aji-31	167	9	knee	knee	NOUN
aji-31	167	10	osteoarthritis	osteoarthritis	NOUN
aji-31	167	11	is	be	AUX
aji-31	167	12	predominantly	predominantly	ADV
aji-31	167	13	related	relate	VERB
aji-31	167	14	to	to	ADP
aji-31	167	15	an	an	DET
aji-31	167	16	unfavorable	unfavorable	ADJ
aji-31	167	17	biomechanical	biomechanical	ADJ
aji-31	167	18	environment	environment	NOUN
aji-31	167	19	at	at	ADP
aji-31	167	20	the	the	DET
aji-31	167	21	joint	joint	NOUN
aji-31	167	22	,	,	PUNCT
aji-31	167	23	which	which	PRON
aji-31	167	24	results	result	VERB
aji-31	167	25	in	in	ADP
aji-31	167	26	mechanical	mechanical	ADJ
aji-31	167	27	demand	demand	NOUN
aji-31	167	28	that	that	PRON
aji-31	167	29	exceeds	exceed	VERB
aji-31	167	30	the	the	DET
aji-31	167	31	ability	ability	NOUN
aji-31	167	32	of	of	ADP
aji-31	167	33	a	a	DET
aji-31	167	34	joint	joint	NOUN
aji-31	167	35	to	to	PART
aji-31	167	36	repair	repair	VERB
aji-31	167	37	and	and	CCONJ
aji-31	167	38	maintain	maintain	VERB
aji-31	167	39	itself	itself	PRON
aji-31	167	40	thereby	thereby	ADV
aji-31	167	41	predisposing	predispose	VERB
aji-31	167	42	the	the	DET
aji-31	167	43	articular	articular	ADJ
aji-31	167	44	cartilage	cartilage	NOUN
aji-31	167	45	to	to	ADP
aji-31	167	46	premature	premature	ADJ
aji-31	167	47	degeneration	degeneration	NOUN
aji-31	167	48	[	[	X
aji-31	167	49	19	19	NUM
aji-31	167	50	]	]	PUNCT
aji-31	167	51	.	.	PUNCT
aji-31	168	1	the	the	DET
aji-31	168	2	pathophysiology	pathophysiology	NOUN
aji-31	168	3	of	of	ADP
aji-31	168	4	the	the	DET
aji-31	168	5	process	process	NOUN
aji-31	168	6	by	by	ADP
aji-31	168	7	which	which	PRON
aji-31	168	8	joint	joint	ADJ
aji-31	168	9	degeneration	degeneration	NOUN
aji-31	168	10	leads	lead	VERB
aji-31	168	11	to	to	ADP
aji-31	168	12	the	the	DET
aji-31	168	13	clinical	clinical	ADJ
aji-31	168	14	syndrome	syndrome	NOUN
aji-31	168	15	of	of	ADP
aji-31	168	16	osteoarthritis	osteoarthritis	NOUN
aji-31	168	17	remains	remains	AUX
aji-31	168	18	poorly	poorly	ADV
aji-31	168	19	understood	understand	VERB
aji-31	168	20	.	.	PUNCT
aji-31	169	1	however	however	ADV
aji-31	169	2	oa	oa	PROPN
aji-31	169	3	mostly	mostly	ADV
aji-31	169	4	involves	involve	VERB
aji-31	169	5	degeneration	degeneration	NOUN
aji-31	169	6	of	of	ADP
aji-31	169	7	cartilage	cartilage	NOUN
aji-31	169	8	,	,	PUNCT
aji-31	169	9	abnormal	abnormal	ADJ
aji-31	169	10	bone	bone	NOUN
aji-31	169	11	remodeling	remodeling	NOUN
aji-31	169	12	,	,	PUNCT
aji-31	169	13	osteophyte	osteophyte	ADJ
aji-31	169	14	formation	formation	NOUN
aji-31	169	15	and	and	CCONJ
aji-31	169	16	joint	joint	ADJ
aji-31	169	17	inflammation	inflammation	NOUN
aji-31	169	18	[	[	X
aji-31	169	19	20	20	NUM
aji-31	169	20	]	]	PUNCT
aji-31	169	21	.	.	PUNCT
aji-31	170	1	in	in	ADP
aji-31	170	2	healthy	healthy	ADJ
aji-31	170	3	joint	joint	ADJ
aji-31	170	4	several	several	ADJ
aji-31	170	5	components	component	NOUN
aji-31	170	6	facilitate	facilitate	VERB
aji-31	170	7	the	the	DET
aji-31	170	8	proper	proper	ADJ
aji-31	170	9	functioning	functioning	NOUN
aji-31	170	10	of	of	ADP
aji-31	170	11	joints	joint	NOUN
aji-31	170	12	such	such	ADJ
aji-31	170	13	as	as	ADP
aji-31	170	14	,	,	PUNCT
aji-31	170	15	meniscus	meniscus	NOUN
aji-31	170	16	(	(	PUNCT
aji-31	170	17	shock	shock	NOUN
aji-31	170	18	absorber	absorber	VERB
aji-31	170	19	)	)	PUNCT
aji-31	170	20	a	a	DET
aji-31	170	21	fibrocartilage	fibrocartilage	NOUN
aji-31	170	22	which	which	PRON
aji-31	170	23	disperse	disperse	VERB
aji-31	170	24	the	the	DET
aji-31	170	25	weight	weight	NOUN
aji-31	170	26	of	of	ADP
aji-31	170	27	the	the	DET
aji-31	170	28	body	body	NOUN
aji-31	170	29	and	and	CCONJ
aji-31	170	30	reduce	reduce	VERB
aji-31	170	31	friction	friction	NOUN
aji-31	170	32	during	during	ADP
aji-31	170	33	movement	movement	NOUN
aji-31	170	34	and	and	CCONJ
aji-31	170	35	mainly	mainly	ADV
aji-31	170	36	composed	compose	VERB
aji-31	170	37	of	of	ADP
aji-31	170	38	water	water	NOUN
aji-31	170	39	,	,	PUNCT
aji-31	170	40	type	type	NOUN
aji-31	170	41	i	i	PRON
aji-31	170	42	collagen	collagen	NOUN
aji-31	170	43	,	,	PUNCT
aji-31	170	44	and	and	CCONJ
aji-31	170	45	proteoglycans	proteoglycan	NOUN
aji-31	170	46	in	in	ADP
aji-31	170	47	its	its	PRON
aji-31	170	48	extra	extra	ADJ
aji-31	170	49	cellular	cellular	ADJ
aji-31	170	50	matrix	matrix	NOUN
aji-31	170	51	[	[	X
aji-31	170	52	21	21	NUM
aji-31	170	53	]	]	PUNCT
aji-31	170	54	.	.	PUNCT
aji-31	171	1	the	the	DET
aji-31	171	2	articular	articular	ADJ
aji-31	171	3	cartilage	cartilage	NOUN
aji-31	171	4	a	a	DET
aji-31	171	5	hyaline	hyaline	ADJ
aji-31	171	6	cartilage	cartilage	NOUN
aji-31	171	7	which	which	PRON
aji-31	171	8	decreases	decrease	VERB
aji-31	171	9	friction	friction	NOUN
aji-31	171	10	and	and	CCONJ
aji-31	171	11	distributes	distribute	VERB
aji-31	171	12	loads	load	NOUN
aji-31	171	13	and	and	CCONJ
aji-31	171	14	mainly	mainly	ADV
aji-31	171	15	composed	compose	VERB
aji-31	171	16	of	of	ADP
aji-31	171	17	water	water	NOUN
aji-31	171	18	,	,	PUNCT
aji-31	171	19	90	90	NUM
aji-31	171	20	%	%	NOUN
aji-31	171	21	type	type	NOUN
aji-31	171	22	ii	ii	NOUN
aji-31	171	23	collagen	collagen	NOUN
aji-31	171	24	and	and	CCONJ
aji-31	171	25	proteoglycans	proteoglycan	NOUN
aji-31	171	26	in	in	ADP
aji-31	171	27	the	the	DET
aji-31	171	28	matrix	matrix	NOUN
aji-31	171	29	[	[	X
aji-31	171	30	22	22	NUM
aji-31	171	31	]	]	PUNCT
aji-31	171	32	.	.	PUNCT
aji-31	172	1	the	the	DET
aji-31	172	2	subchondral	subchondral	ADJ
aji-31	172	3	bone	bone	NOUN
aji-31	172	4	which	which	PRON
aji-31	172	5	attenuates	attenuate	VERB
aji-31	172	6	forces	force	NOUN
aji-31	172	7	generated	generate	VERB
aji-31	172	8	through	through	ADP
aji-31	172	9	locomotion	locomotion	NOUN
aji-31	172	10	,	,	PUNCT
aji-31	172	11	with	with	ADP
aji-31	172	12	the	the	DET
aji-31	172	13	compact	compact	ADJ
aji-31	172	14	subchondral	subchondral	ADJ
aji-31	172	15	bone	bone	NOUN
aji-31	172	16	plate	plate	NOUN
aji-31	172	17	providing	provide	VERB
aji-31	172	18	firm	firm	ADJ
aji-31	172	19	support	support	NOUN
aji-31	172	20	to	to	ADP
aji-31	172	21	the	the	DET
aji-31	172	22	joint	joint	ADJ
aji-31	172	23	and	and	CCONJ
aji-31	172	24	mainly	mainly	ADV
aji-31	172	25	composed	compose	VERB
aji-31	172	26	of	of	ADP
aji-31	172	27	type	type	NOUN
aji-31	172	28	i	i	PRON
aji-31	172	29	collagen	collagen	VERB
aji-31	172	30	.	.	PUNCT
aji-31	173	1	the	the	DET
aji-31	173	2	synovium	synovium	NOUN
aji-31	173	3	which	which	PRON
aji-31	173	4	produces	produce	VERB
aji-31	173	5	synovial	synovial	ADJ
aji-31	173	6	fluids	fluid	NOUN
aji-31	173	7	that	that	PRON
aji-31	173	8	functions	function	VERB
aji-31	173	9	in	in	ADP
aji-31	173	10	reducing	reduce	VERB
aji-31	173	11	friction	friction	NOUN
aji-31	173	12	by	by	ADP
aji-31	173	13	lubricating	lubricate	VERB
aji-31	173	14	the	the	DET
aji-31	173	15	joint	joint	ADJ
aji-31	173	16	,	,	PUNCT
aji-31	173	17	absorbing	absorb	VERB
aji-31	173	18	shocks	shock	NOUN
aji-31	173	19	,	,	PUNCT
aji-31	173	20	supplying	supply	VERB
aji-31	173	21	oxygen	oxygen	NOUN
aji-31	173	22	,	,	PUNCT
aji-31	173	23	nutrients	nutrient	NOUN
aji-31	173	24	and	and	CCONJ
aji-31	173	25	removing	remove	VERB
aji-31	173	26	carbon	carbon	NOUN
aji-31	173	27	dioxide	dioxide	NOUN
aji-31	173	28	and	and	CCONJ
aji-31	173	29	metabolic	metabolic	NOUN
aji-31	173	30	wastes	waste	NOUN
aji-31	173	31	from	from	ADP
aji-31	173	32	the	the	DET
aji-31	173	33	chondrocytes	chondrocyte	NOUN
aji-31	173	34	within	within	ADP
aji-31	173	35	articular	articular	ADJ
aji-31	173	36	cartilage	cartilage	NOUN
aji-31	174	1	[	[	X
aji-31	174	2	23	23	NUM
aji-31	174	3	]	]	PUNCT
aji-31	174	4	.	.	PUNCT
aji-31	175	1	synovial	synovial	ADJ
aji-31	175	2	membrane	membrane	NOUN
aji-31	175	3	composed	compose	VERB
aji-31	175	4	of	of	ADP
aji-31	175	5	two	two	NUM
aji-31	175	6	synoviocytes	synoviocyte	NOUN
aji-31	175	7	;	;	PUNCT
aji-31	175	8	synovial	synovial	ADJ
aji-31	175	9	fibroblast	fibroblast	ADJ
aji-31	175	10	and	and	CCONJ
aji-31	175	11	synovial	synovial	ADJ
aji-31	175	12	macrophages	macrophage	NOUN
aji-31	175	13	.	.	PUNCT
aji-31	176	1	the	the	DET
aji-31	176	2	synovial	synovial	ADJ
aji-31	176	3	fibroblast	fibroblast	NOUN
aji-31	176	4	produces	produce	VERB
aji-31	176	5	the	the	DET
aji-31	176	6	extracellular	extracellular	ADJ
aji-31	176	7	matrix	matrix	NOUN
aji-31	176	8	components	component	NOUN
aji-31	176	9	of	of	ADP
aji-31	176	10	the	the	DET
aji-31	176	11	synovial	synovial	ADJ
aji-31	176	12	fluid	fluid	NOUN
aji-31	176	13	and	and	CCONJ
aji-31	176	14	thus	thus	ADV
aji-31	176	15	is	be	AUX
aji-31	176	16	important	important	ADJ
aji-31	176	17	for	for	ADP
aji-31	176	18	cartilage	cartilage	NOUN
aji-31	176	19	integrity	integrity	NOUN
aji-31	176	20	and	and	CCONJ
aji-31	176	21	lubrication	lubrication	NOUN
aji-31	176	22	of	of	ADP
aji-31	176	23	the	the	DET
aji-31	176	24	joint	joint	NOUN
aji-31	176	25	,	,	PUNCT
aji-31	176	26	while	while	SCONJ
aji-31	176	27	the	the	DET
aji-31	176	28	synovial	synovial	ADJ
aji-31	176	29	macrophages	macrophage	NOUN
aji-31	176	30	remain	remain	VERB
aji-31	176	31	relatively	relatively	ADV
aji-31	176	32	quiescent	quiescent	ADJ
aji-31	176	33	in	in	ADP
aji-31	176	34	the	the	DET
aji-31	176	35	healthy	healthy	ADJ
aji-31	176	36	joint	joint	NOUN
aji-31	176	37	;	;	PUNCT
aji-31	176	38	they	they	PRON
aji-31	176	39	become	become	VERB
aji-31	176	40	activated	activated	ADJ
aji-31	176	41	in	in	ADP
aji-31	176	42	the	the	DET
aji-31	176	43	inflamed	inflame	VERB
aji-31	176	44	joint	joint	NOUN
aji-31	176	45	and	and	CCONJ
aji-31	176	46	,	,	PUNCT
aji-31	176	47	along	along	ADP
aji-31	176	48	with	with	ADP
aji-31	176	49	infiltrating	infiltrating	ADJ
aji-31	176	50	monocytes	monocyte	NOUN
aji-31	176	51	/	/	SYM
aji-31	176	52	macrophages	macrophage	NOUN
aji-31	176	53	,	,	PUNCT
aji-31	176	54	regulate	regulate	VERB
aji-31	176	55	secretion	secretion	NOUN
aji-31	176	56	of	of	ADP
aji-31	176	57	pro	pro	ADJ
aji-31	176	58	-	-	ADJ
aji-31	176	59	inflammatory	inflammatory	ADJ
aji-31	176	60	cytokines	cytokine	NOUN
aji-31	176	61	[	[	X
aji-31	176	62	24,25	24,25	NUM
aji-31	176	63	]	]	PUNCT
aji-31	176	64	.	.	PUNCT
aji-31	177	1	several	several	ADJ
aji-31	177	2	abnormalities	abnormality	NOUN
aji-31	177	3	such	such	ADJ
aji-31	177	4	as	as	ADP
aji-31	177	5	mechanical	mechanical	ADJ
aji-31	177	6	abrasion	abrasion	NOUN
aji-31	177	7	in	in	ADP
aji-31	177	8	the	the	DET
aji-31	177	9	knee	knee	NOUN
aji-31	177	10	have	have	AUX
aji-31	177	11	been	be	AUX
aji-31	177	12	found	find	VERB
aji-31	177	13	to	to	PART
aji-31	177	14	promote	promote	VERB
aji-31	177	15	oa	oa	INTJ
aji-31	177	16	,	,	PUNCT
aji-31	177	17	which	which	PRON
aji-31	177	18	is	be	AUX
aji-31	177	19	mostly	mostly	ADV
aji-31	177	20	seen	see	VERB
aji-31	177	21	in	in	ADP
aji-31	177	22	the	the	DET
aji-31	177	23	older	old	ADJ
aji-31	177	24	age	age	NOUN
aji-31	177	25	and	and	CCONJ
aji-31	177	26	can	can	AUX
aji-31	177	27	ultimately	ultimately	ADV
aji-31	177	28	leads	lead	VERB
aji-31	177	29	to	to	ADP
aji-31	177	30	the	the	DET
aji-31	177	31	progressive	progressive	ADJ
aji-31	177	32	degenerative	degenerative	ADJ
aji-31	177	33	changes	change	NOUN
aji-31	177	34	in	in	ADP
aji-31	177	35	the	the	DET
aji-31	177	36	proper	proper	ADJ
aji-31	177	37	functioning	functioning	NOUN
aji-31	177	38	of	of	ADP
aji-31	177	39	the	the	DET
aji-31	177	40	joints	joint	NOUN
aji-31	177	41	.	.	PUNCT
aji-31	178	1	furthermore	furthermore	ADV
aji-31	178	2	,	,	PUNCT
aji-31	178	3	the	the	DET
aji-31	178	4	innate	innate	ADJ
aji-31	178	5	immune	immune	ADJ
aji-31	178	6	system	system	NOUN
aji-31	178	7	plays	play	VERB
aji-31	178	8	a	a	DET
aji-31	178	9	role	role	NOUN
aji-31	178	10	in	in	ADP
aji-31	178	11	oa	oa	PROPN
aji-31	178	12	progression	progression	NOUN
aji-31	178	13	through	through	ADP
aji-31	178	14	the	the	DET
aji-31	178	15	activation	activation	NOUN
aji-31	178	16	of	of	ADP
aji-31	178	17	both	both	CCONJ
aji-31	178	18	the	the	DET
aji-31	178	19	complement	complement	NOUN
aji-31	178	20	and	and	CCONJ
aji-31	178	21	alternative	alternative	ADJ
aji-31	178	22	pathways	pathway	NOUN
aji-31	178	23	of	of	ADP
aji-31	178	24	inflammation	inflammation	NOUN
aji-31	178	25	,	,	PUNCT
aji-31	178	26	once	once	ADV
aji-31	178	27	activated	activate	VERB
aji-31	178	28	;	;	PUNCT
aji-31	178	29	it	it	PRON
aji-31	178	30	leads	lead	VERB
aji-31	178	31	to	to	ADP
aji-31	178	32	an	an	DET
aji-31	178	33	inflammatory	inflammatory	ADJ
aji-31	178	34	response	response	NOUN
aji-31	178	35	that	that	PRON
aji-31	178	36	is	be	AUX
aji-31	178	37	a	a	DET
aji-31	178	38	major	major	ADJ
aji-31	178	39	driver	driver	NOUN
aji-31	178	40	of	of	ADP
aji-31	178	41	the	the	DET
aji-31	178	42	disease	disease	NOUN
aji-31	178	43	[	[	X
aji-31	178	44	25	25	NUM
aji-31	178	45	]	]	PUNCT
aji-31	178	46	.	.	PUNCT
aji-31	179	1	6	6	X
aji-31	179	2	.	.	X
aji-31	179	3	diagnosis	diagnosis	NOUN
aji-31	179	4	of	of	ADP
aji-31	179	5	osteoarthritis	osteoarthritis	NOUN
aji-31	179	6			NOUN
aji-31	180	1	x	x	X
aji-31	180	2	-	-	NOUN
aji-31	180	3	ray	ray	NOUN
aji-31	180	4	of	of	ADP
aji-31	180	5	affected	affect	VERB
aji-31	180	6	joints	joint	NOUN
aji-31	180	7	will	will	AUX
aji-31	180	8	show	show	VERB
aji-31	180	9	a	a	DET
aji-31	180	10	loss	loss	NOUN
aji-31	180	11	of	of	ADP
aji-31	180	12	the	the	DET
aji-31	180	13	joint	joint	ADJ
aji-31	180	14	space	space	NOUN
aji-31	180	15	.	.	PUNCT
aji-31	181	1	in	in	ADP
aji-31	181	2	more	more	ADV
aji-31	181	3	advanced	advanced	ADJ
aji-31	181	4	cases	case	NOUN
aji-31	181	5	,	,	PUNCT
aji-31	181	6	there	there	PRON
aji-31	181	7	may	may	AUX
aji-31	181	8	be	be	AUX
aji-31	181	9	bone	bone	NOUN
aji-31	181	10	spurs	spur	NOUN
aji-31	181	11	or	or	CCONJ
aji-31	181	12	evidence	evidence	NOUN
aji-31	181	13	of	of	ADP
aji-31	181	14	worn	wear	VERB
aji-31	181	15	-	-	PUNCT
aji-31	181	16	down	down	ADP
aji-31	181	17	ends	end	NOUN
aji-31	181	18	of	of	ADP
aji-31	181	19	the	the	DET
aji-31	181	20	bones	bone	NOUN
aji-31	181	21	in	in	ADP
aji-31	181	22	the	the	DET
aji-31	181	23	affected	affected	ADJ
aji-31	181	24	joint	joint	NOUN
aji-31	181	25	[	[	X
aji-31	181	26	26	26	NUM
aji-31	181	27	]	]	PUNCT
aji-31	181	28	.	.	PUNCT
aji-31	182	1			PROPN
aji-31	182	2	magnetic	magnetic	ADJ
aji-31	182	3	resonance	resonance	NOUN
aji-31	182	4	imaging	imaging	NOUN
aji-31	182	5	(	(	PUNCT
aji-31	182	6	mri	mri	NOUN
aji-31	182	7	)	)	PUNCT
aji-31	182	8	has	have	VERB
aji-31	182	9	a	a	DET
aji-31	182	10	tomographic	tomographic	ADJ
aji-31	182	11	viewing	view	VERB
aji-31	182	12	perspective	perspective	NOUN
aji-31	182	13	and	and	CCONJ
aji-31	182	14	thus	thus	ADV
aji-31	182	15	provides	provide	VERB
aji-31	182	16	cross	cross	ADJ
aji-31	182	17	-	-	ADJ
aji-31	182	18	sectional	sectional	ADJ
aji-31	182	19	images	image	NOUN
aji-31	182	20	of	of	ADP
aji-31	182	21	the	the	DET
aji-31	182	22	anatomy	anatomy	NOUN
aji-31	182	23	free	free	ADJ
aji-31	182	24	of	of	ADP
aji-31	182	25	the	the	DET
aji-31	182	26	projectional	projectional	ADJ
aji-31	182	27	limitations	limitation	NOUN
aji-31	182	28	of	of	ADP
aji-31	182	29	radiography	radiography	NOUN
aji-31	182	30	,	,	PUNCT
aji-31	182	31	the	the	DET
aji-31	182	32	technique	technique	NOUN
aji-31	182	33	is	be	AUX
aji-31	182	34	uniquely	uniquely	ADV
aji-31	182	35	able	able	ADJ
aji-31	182	36	to	to	PART
aji-31	182	37	depict	depict	VERB
aji-31	182	38	all	all	DET
aji-31	182	39	the	the	DET
aji-31	182	40	components	component	NOUN
aji-31	182	41	of	of	ADP
aji-31	182	42	the	the	DET
aji-31	182	43	joint	joint	NOUN
aji-31	182	44	,	,	PUNCT
aji-31	182	45	their	their	PRON
aji-31	182	46	pathologies	pathology	NOUN
aji-31	182	47	,	,	PUNCT
aji-31	182	48	articular	articular	ADJ
aji-31	182	49	cartilage	cartilage	NOUN
aji-31	182	50	,	,	PUNCT
aji-31	182	51	meniscus	meniscus	NOUN
aji-31	182	52	,	,	PUNCT
aji-31	182	53	intraarticular	intraarticular	ADJ
aji-31	182	54	ligaments	ligament	NOUN
aji-31	182	55	,	,	PUNCT
aji-31	182	56	synovium	synovium	NOUN
aji-31	182	57	,	,	PUNCT
aji-31	182	58	effusion	effusion	NOUN
aji-31	182	59	,	,	PUNCT
aji-31	182	60	bone	bone	NOUN
aji-31	182	61	attrition	attrition	NOUN
aji-31	182	62	,	,	PUNCT
aji-31	182	63	bone	bone	NOUN
aji-31	182	64	marrow	marrow	NOUN
aji-31	182	65	lesions	lesion	NOUN
aji-31	182	66	,	,	PUNCT
aji-31	182	67	subchondral	subchondral	ADJ
aji-31	182	68	cysts	cyst	NOUN
aji-31	182	69	,	,	PUNCT
aji-31	182	70	and	and	CCONJ
aji-31	182	71	intraand	intraand	X
aji-31	182	72	periarticular	periarticular	ADJ
aji-31	182	73	cystic	cystic	ADJ
aji-31	182	74	lesions	lesion	NOUN
aji-31	182	75	[	[	X
aji-31	182	76	27	27	NUM
aji-31	182	77	]	]	PUNCT
aji-31	182	78	.	.	PUNCT
aji-31	183	1			NOUN
aji-31	183	2	arthroscopy	arthroscopy	NOUN
aji-31	183	3	:	:	PUNCT
aji-31	183	4	is	be	AUX
aji-31	183	5	a	a	PRON
aji-31	183	6	is	be	AUX
aji-31	183	7	a	a	DET
aji-31	183	8	surgical	surgical	ADJ
aji-31	183	9	procedure	procedure	NOUN
aji-31	183	10	orthopedic	orthopedic	ADJ
aji-31	183	11	surgeons	surgeon	NOUN
aji-31	183	12	use	use	VERB
aji-31	183	13	to	to	PART
aji-31	183	14	visualize	visualize	VERB
aji-31	183	15	,	,	PUNCT
aji-31	183	16	diagnose	diagnose	NOUN
aji-31	183	17	,	,	PUNCT
aji-31	183	18	and	and	CCONJ
aji-31	183	19	treat	treat	VERB
aji-31	183	20	problems	problem	NOUN
aji-31	183	21	inside	inside	ADP
aji-31	183	22	a	a	DET
aji-31	183	23	joint	joint	NOUN
aji-31	183	24	by	by	ADP
aji-31	183	25	inserting	insert	VERB
aji-31	183	26	a	a	DET
aji-31	183	27	narrow	narrow	ADJ
aji-31	183	28	tube	tube	NOUN
aji-31	183	29	attached	attach	VERB
aji-31	183	30	to	to	ADP
aji-31	183	31	a	a	DET
aji-31	183	32	fiberoptic	fiberoptic	ADJ
aji-31	183	33	video	video	NOUN
aji-31	183	34	camera	camera	NOUN
aji-31	183	35	through	through	ADP
aji-31	183	36	a	a	DET
aji-31	183	37	small	small	ADJ
aji-31	183	38	incision	incision	NOUN
aji-31	183	39	which	which	PRON
aji-31	183	40	gives	give	VERB
aji-31	183	41	a	a	DET
aji-31	183	42	clear	clear	ADJ
aji-31	183	43	view	view	NOUN
aji-31	183	44	of	of	ADP
aji-31	183	45	the	the	DET
aji-31	183	46	pathological	pathological	ADJ
aji-31	183	47	changes	change	NOUN
aji-31	183	48	inside	inside	ADP
aji-31	183	49	the	the	DET
aji-31	183	50	joint	joint	NOUN
aji-31	183	51	[	[	X
aji-31	183	52	28	28	NUM
aji-31	183	53	]	]	PUNCT
aji-31	183	54	.	.	PUNCT
aji-31	184	1			NOUN
aji-31	184	2	ultrasonography	ultrasonography	NOUN
aji-31	184	3	is	be	AUX
aji-31	184	4	a	a	DET
aji-31	184	5	modern	modern	ADJ
aji-31	184	6	ultrasound	ultrasound	NOUN
aji-31	184	7	technique	technique	NOUN
aji-31	184	8	which	which	PRON
aji-31	184	9	uses	use	VERB
aji-31	184	10	high	high	ADJ
aji-31	184	11	-	-	PUNCT
aji-31	184	12	frequency	frequency	NOUN
aji-31	184	13	sound	sound	NOUN
aji-31	184	14	waves	wave	NOUN
aji-31	184	15	to	to	PART
aji-31	184	16	produce	produce	VERB
aji-31	184	17	images	image	NOUN
aji-31	184	18	of	of	ADP
aji-31	184	19	internal	internal	ADJ
aji-31	184	20	organs	organ	NOUN
aji-31	184	21	and	and	CCONJ
aji-31	184	22	other	other	ADJ
aji-31	184	23	tissue	tissue	NOUN
aji-31	185	1	[	[	X
aji-31	185	2	29	29	NUM
aji-31	185	3	]	]	PUNCT
aji-31	185	4	.	.	PUNCT
aji-31	186	1	7	7	X
aji-31	186	2	.	.	X
aji-31	186	3	therapeutic	therapeutic	ADJ
aji-31	186	4	targets	target	NOUN
aji-31	186	5	of	of	ADP
aji-31	186	6	osteoarthritis	osteoarthritis	NOUN
aji-31	186	7	7.1	7.1	NUM
aji-31	186	8	tnf	tnf	PROPN
aji-31	186	9	-	-	PUNCT
aji-31	186	10	α	α	PROPN
aji-31	186	11	blockers	blocker	NOUN
aji-31	186	12	tnf	tnf	PROPN
aji-31	186	13	-	-	PUNCT
aji-31	186	14	α	α	PROPN
aji-31	186	15	is	be	AUX
aji-31	186	16	an	an	DET
aji-31	186	17	inflammatory	inflammatory	ADJ
aji-31	186	18	cytokine	cytokine	NOUN
aji-31	186	19	produced	produce	VERB
aji-31	186	20	by	by	ADP
aji-31	186	21	monocytes	monocyte	NOUN
aji-31	186	22	/	/	SYM
aji-31	186	23	macrophages	macrophage	NOUN
aji-31	186	24	during	during	ADP
aji-31	186	25	acute	acute	ADJ
aji-31	186	26	inflammation	inflammation	NOUN
aji-31	186	27	,	,	PUNCT
aji-31	186	28	it	it	PRON
aji-31	186	29	plays	play	VERB
aji-31	186	30	significant	significant	ADJ
aji-31	186	31	role	role	NOUN
aji-31	186	32	in	in	ADP
aji-31	186	33	the	the	DET
aji-31	186	34	pathogenesis	pathogenesis	NOUN
aji-31	186	35	of	of	ADP
aji-31	186	36	oa	oa	PROPN
aji-31	186	37	.	.	PROPN
aji-31	186	38	adalimumab	adalimumab	PROPN
aji-31	186	39	is	be	AUX
aji-31	186	40	a	a	DET
aji-31	186	41	human	human	ADJ
aji-31	186	42	monoclonal	monoclonal	NOUN
aji-31	186	43	antibody	antibody	NOUN
aji-31	186	44	bioengineered	bioengineere	VERB
aji-31	186	45	to	to	PART
aji-31	186	46	prevent	prevent	VERB
aji-31	186	47	the	the	DET
aji-31	186	48	binding	binding	NOUN
aji-31	186	49	of	of	ADP
aji-31	186	50	tnf	tnf	PROPN
aji-31	186	51	-	-	PUNCT
aji-31	186	52	α	α	NOUN
aji-31	186	53	to	to	ADP
aji-31	186	54	its	its	PRON
aji-31	186	55	receptor	receptor	NOUN
aji-31	186	56	and	and	CCONJ
aji-31	186	57	inhibit	inhibit	VERB
aji-31	186	58	the	the	DET
aji-31	186	59	progression	progression	NOUN
aji-31	186	60	of	of	ADP
aji-31	186	61	osteoarthritis	osteoarthritis	NOUN
aji-31	186	62	.	.	PUNCT
aji-31	187	1	a	a	DET
aji-31	187	2	12	12	NUM
aji-31	187	3	-	-	PUNCT
aji-31	187	4	month	month	NOUN
aji-31	187	5	randomised	randomise	VERB
aji-31	187	6	,	,	PUNCT
aji-31	187	7	double	double	ADJ
aji-31	187	8	-	-	PUNCT
aji-31	187	9	blind	blind	ADJ
aji-31	187	10	,	,	PUNCT
aji-31	187	11	placebo	placebo	NOUN
aji-31	187	12	-	-	PUNCT
aji-31	187	13	controlled	control	VERB
aji-31	187	14	trial	trial	NOUN
aji-31	187	15	evaluate	evaluate	VERB
aji-31	187	16	subcutaneous	subcutaneous	ADJ
aji-31	187	17	administration	administration	NOUN
aji-31	187	18	of	of	ADP
aji-31	187	19	40	40	NUM
aji-31	187	20	mg	mg	PROPN
aji-31	187	21	adalimumab	adalimumab	NOUN
aji-31	187	22	every	every	DET
aji-31	187	23	two	two	NUM
aji-31	187	24	weeks	week	NOUN
aji-31	187	25	in	in	ADP
aji-31	187	26	60	60	NUM
aji-31	187	27	patients	patient	NOUN
aji-31	187	28	with	with	ADP
aji-31	187	29	erosive	erosive	ADJ
aji-31	187	30	hand	hand	NOUN
aji-31	187	31	oa	oa	INTJ
aji-31	187	32	,	,	PUNCT
aji-31	187	33	however	however	ADV
aji-31	187	34	the	the	DET
aji-31	187	35	tolerability	tolerability	NOUN
aji-31	187	36	and	and	CCONJ
aji-31	187	37	safety	safety	NOUN
aji-31	187	38	profiles	profile	NOUN
aji-31	187	39	of	of	ADP
aji-31	187	40	adalimumab	adalimumab	NOUN
aji-31	187	41	on	on	ADP
aji-31	187	42	those	those	DET
aji-31	187	43	patients	patient	NOUN
aji-31	187	44	were	be	AUX
aji-31	187	45	very	very	ADV
aji-31	187	46	good	good	ADJ
aji-31	187	47	and	and	CCONJ
aji-31	187	48	resulting	result	VERB
aji-31	187	49	to	to	ADP
aji-31	187	50	successful	successful	ADJ
aji-31	187	51	shehu	shehu	NOUN
aji-31	187	52	et	et	PROPN
aji-31	187	53	al	al	PROPN
aji-31	187	54	.	.	PROPN
aji-31	187	55	;	;	PUNCT
aji-31	188	1	aji	aji	PROPN
aji-31	188	2	,	,	PUNCT
aji-31	188	3	3(1	3(1	NUM
aji-31	188	4	):	):	PUNCT
aji-31	188	5	223	223	NUM
aji-31	188	6	-	-	SYM
aji-31	188	7	232	232	NUM
aji-31	188	8	,	,	PUNCT
aji-31	188	9	2020	2020	NUM
aji-31	188	10	;	;	PUNCT
aji-31	188	11	article	article	NOUN
aji-31	188	12	no.aji.57637	no.aji.57637	ADV
aji-31	188	13	228	228	NUM
aji-31	188	14	neutralization	neutralization	NOUN
aji-31	188	15	of	of	ADP
aji-31	188	16	the	the	DET
aji-31	188	17	tnfα	tnfα	NOUN
aji-31	188	18	there	there	ADV
aji-31	188	19	by	by	ADP
aji-31	188	20	slowing	slow	VERB
aji-31	188	21	the	the	DET
aji-31	188	22	progression	progression	NOUN
aji-31	188	23	of	of	ADP
aji-31	188	24	structural	structural	ADJ
aji-31	188	25	damage	damage	NOUN
aji-31	188	26	in	in	ADP
aji-31	188	27	erosive	erosive	ADJ
aji-31	188	28	interphalangeal	interphalangeal	ADJ
aji-31	188	29	finger	finger	NOUN
aji-31	188	30	joint	joint	ADJ
aji-31	188	31	osteoarthritis	osteoarthritis	NOUN
aji-31	188	32	[	[	X
aji-31	188	33	30	30	NUM
aji-31	188	34	]	]	PUNCT
aji-31	188	35	.	.	PUNCT
aji-31	189	1	anti	anti	ADJ
aji-31	189	2	-	-	ADJ
aji-31	189	3	tnf	tnf	ADJ
aji-31	189	4	-	-	PUNCT
aji-31	189	5	α	α	NOUN
aji-31	189	6	therapy	therapy	NOUN
aji-31	189	7	with	with	ADP
aji-31	189	8	infliximab	infliximab	NOUN
aji-31	189	9	(	(	PUNCT
aji-31	189	10	a	a	DET
aji-31	189	11	chimeric	chimeric	ADJ
aji-31	189	12	monoclonal	monoclonal	NOUN
aji-31	189	13	antibody	antibody	NOUN
aji-31	189	14	)	)	PUNCT
aji-31	189	15	was	be	AUX
aji-31	189	16	reported	report	VERB
aji-31	189	17	to	to	PART
aji-31	189	18	yield	yield	VERB
aji-31	189	19	effective	effective	ADJ
aji-31	189	20	treatment	treatment	NOUN
aji-31	189	21	and	and	CCONJ
aji-31	189	22	reduce	reduce	VERB
aji-31	189	23	the	the	DET
aji-31	189	24	incident	incident	NOUN
aji-31	189	25	of	of	ADP
aji-31	189	26	secondary	secondary	ADJ
aji-31	189	27	oa	oa	NOUN
aji-31	189	28	via	via	ADP
aji-31	189	29	other	other	ADJ
aji-31	189	30	pathways	pathway	NOUN
aji-31	190	1	[	[	X
aji-31	190	2	31	31	NUM
aji-31	190	3	]	]	PUNCT
aji-31	190	4	.	.	PUNCT
aji-31	191	1	7.2	7.2	NUM
aji-31	191	2	il-1β	il-1β	PROPN
aji-31	191	3	inhibitor	inhibitor	NOUN
aji-31	191	4	il-1β	il-1β	PROPN
aji-31	191	5	also	also	ADV
aji-31	191	6	known	know	VERB
aji-31	191	7	as	as	ADP
aji-31	191	8	leukocytic	leukocytic	ADJ
aji-31	191	9	pyrogen	pyrogen	NOUN
aji-31	191	10	,	,	PUNCT
aji-31	191	11	is	be	AUX
aji-31	191	12	a	a	DET
aji-31	191	13	key	key	ADJ
aji-31	191	14	pathogenic	pathogenic	ADJ
aji-31	191	15	factor	factor	NOUN
aji-31	191	16	in	in	ADP
aji-31	191	17	oa	oa	NOUN
aji-31	191	18	.	.	PUNCT
aji-31	192	1	hence	hence	ADV
aji-31	192	2	use	use	NOUN
aji-31	192	3	of	of	ADP
aji-31	192	4	diacerein	diacerein	ADJ
aji-31	192	5	which	which	PRON
aji-31	192	6	is	be	AUX
aji-31	192	7	an	an	DET
aji-31	192	8	il-1β	il-1β	PROPN
aji-31	192	9	inhibitor	inhibitor	NOUN
aji-31	192	10	,	,	PUNCT
aji-31	192	11	reduces	reduce	VERB
aji-31	192	12	the	the	DET
aji-31	192	13	number	number	NOUN
aji-31	192	14	of	of	ADP
aji-31	192	15	il-1	il-1	ADP
aji-31	192	16	receptors	receptor	NOUN
aji-31	192	17	,	,	PUNCT
aji-31	192	18	thereby	thereby	ADV
aji-31	192	19	resulting	result	VERB
aji-31	192	20	to	to	ADP
aji-31	192	21	reduction	reduction	NOUN
aji-31	192	22	in	in	ADP
aji-31	192	23	functional	functional	ADJ
aji-31	192	24	il-1	il-1	ADP
aji-31	192	25	heterodimer	heterodimer	NOUN
aji-31	192	26	receptor	receptor	NOUN
aji-31	192	27	complexes	complex	NOUN
aji-31	192	28	and	and	CCONJ
aji-31	192	29	ultimately	ultimately	ADV
aji-31	192	30	lowers	lower	VERB
aji-31	192	31	the	the	DET
aji-31	192	32	disease	disease	NOUN
aji-31	192	33	progression	progression	NOUN
aji-31	192	34	[	[	X
aji-31	192	35	32	32	NUM
aji-31	192	36	]	]	PUNCT
aji-31	192	37	.	.	PUNCT
aji-31	193	1	a	a	DET
aji-31	193	2	study	study	NOUN
aji-31	193	3	of	of	ADP
aji-31	193	4	a	a	DET
aji-31	193	5	symptomatic	symptomatic	ADJ
aji-31	193	6	slow‐acting	slow‐acting	NOUN
aji-31	193	7	oa	oa	ADP
aji-31	193	8	drug	drug	NOUN
aji-31	193	9	which	which	PRON
aji-31	193	10	accesses	access	VERB
aji-31	193	11	the	the	DET
aji-31	193	12	primary	primary	ADJ
aji-31	193	13	outcome	outcome	NOUN
aji-31	193	14	for	for	ADP
aji-31	193	15	2	2	NUM
aji-31	193	16	months	month	NOUN
aji-31	193	17	after	after	ADP
aji-31	193	18	the	the	DET
aji-31	193	19	end	end	NOUN
aji-31	193	20	of	of	ADP
aji-31	193	21	a	a	DET
aji-31	193	22	3	3	NUM
aji-31	193	23	month	month	NOUN
aji-31	193	24	treatment	treatment	NOUN
aji-31	193	25	period	period	NOUN
aji-31	193	26	shows	show	VERB
aji-31	193	27	that	that	PRON
aji-31	193	28	diacerein	diacerein	ADV
aji-31	193	29	is	be	AUX
aji-31	193	30	safe	safe	ADJ
aji-31	193	31	and	and	CCONJ
aji-31	193	32	has	have	VERB
aji-31	193	33	a	a	DET
aji-31	193	34	significant	significant	ADJ
aji-31	193	35	effective	effective	ADJ
aji-31	193	36	for	for	ADP
aji-31	193	37	the	the	DET
aji-31	193	38	treatment	treatment	NOUN
aji-31	193	39	of	of	ADP
aji-31	193	40	knee	knee	NOUN
aji-31	193	41	oa	oa	X
aji-31	194	1	[	[	X
aji-31	194	2	33	33	NUM
aji-31	194	3	]	]	PUNCT
aji-31	194	4	.	.	PUNCT
aji-31	195	1	another	another	DET
aji-31	195	2	study	study	NOUN
aji-31	195	3	confirmed	confirm	VERB
aji-31	195	4	that	that	SCONJ
aji-31	195	5	symptomatic	symptomatic	ADJ
aji-31	195	6	benefit	benefit	NOUN
aji-31	195	7	provided	provide	VERB
aji-31	195	8	by	by	ADP
aji-31	195	9	diacerein	diacerein	NOUN
aji-31	195	10	in	in	ADP
aji-31	195	11	terms	term	NOUN
aji-31	195	12	of	of	ADP
aji-31	195	13	pain	pain	NOUN
aji-31	195	14	reduction	reduction	NOUN
aji-31	195	15	is	be	AUX
aji-31	195	16	minimal	minimal	ADJ
aji-31	195	17	;	;	PUNCT
aji-31	195	18	the	the	DET
aji-31	195	19	small	small	ADJ
aji-31	195	20	changes	change	NOUN
aji-31	195	21	observed	observe	VERB
aji-31	195	22	in	in	ADP
aji-31	195	23	the	the	DET
aji-31	195	24	joint	joint	ADJ
aji-31	195	25	space	space	NOUN
aji-31	195	26	narrowing	narrowing	NOUN
aji-31	195	27	is	be	AUX
aji-31	195	28	of	of	ADP
aji-31	195	29	questionable	questionable	ADJ
aji-31	195	30	clinical	clinical	ADJ
aji-31	195	31	relevance	relevance	NOUN
aji-31	195	32	and	and	CCONJ
aji-31	195	33	was	be	AUX
aji-31	195	34	observed	observe	VERB
aji-31	195	35	only	only	ADV
aji-31	195	36	for	for	ADP
aji-31	195	37	oa	oa	NOUN
aji-31	195	38	of	of	ADP
aji-31	195	39	the	the	DET
aji-31	195	40	hip	hip	NOUN
aji-31	196	1	[	[	X
aji-31	196	2	34	34	NUM
aji-31	196	3	]	]	PUNCT
aji-31	196	4	.	.	PUNCT
aji-31	197	1	in	in	ADP
aji-31	197	2	vitro	vitro	X
aji-31	197	3	and	and	CCONJ
aji-31	197	4	experimental	experimental	ADJ
aji-31	197	5	models	model	NOUN
aji-31	197	6	showed	show	VERB
aji-31	197	7	a	a	DET
aji-31	197	8	reduction	reduction	NOUN
aji-31	197	9	in	in	ADP
aji-31	197	10	cartilage	cartilage	NOUN
aji-31	197	11	destruction	destruction	NOUN
aji-31	197	12	with	with	ADP
aji-31	197	13	il-1	il-1	X
aji-31	197	14	by	by	ADP
aji-31	197	15	il-1	il-1	ADP
aji-31	197	16	receptor	receptor	NOUN
aji-31	197	17	antagonists	antagonist	NOUN
aji-31	197	18	[	[	X
aji-31	197	19	35	35	NUM
aji-31	197	20	]	]	PUNCT
aji-31	197	21	.	.	PUNCT
aji-31	198	1	one	one	NUM
aji-31	198	2	of	of	ADP
aji-31	198	3	recent	recent	ADJ
aji-31	198	4	articles	article	NOUN
aji-31	198	5	shows	show	VERB
aji-31	198	6	a	a	DET
aji-31	198	7	possible	possible	ADJ
aji-31	198	8	benefit	benefit	NOUN
aji-31	198	9	in	in	ADP
aji-31	198	10	using	use	VERB
aji-31	198	11	higher	high	ADJ
aji-31	198	12	doses	dose	NOUN
aji-31	198	13	of	of	ADP
aji-31	198	14	kineret	kineret	NOUN
aji-31	198	15	(	(	PUNCT
aji-31	198	16	150	150	NUM
aji-31	198	17	-	-	SYM
aji-31	198	18	200	200	NUM
aji-31	198	19	mg	mg	NOUN
aji-31	198	20	)	)	PUNCT
aji-31	198	21	in	in	ADP
aji-31	198	22	the	the	DET
aji-31	198	23	treatment	treatment	NOUN
aji-31	198	24	of	of	ADP
aji-31	198	25	osteoarthritis	osteoarthritis	NOUN
aji-31	198	26	of	of	ADP
aji-31	198	27	large	large	ADJ
aji-31	198	28	joints	joint	NOUN
aji-31	198	29	and	and	CCONJ
aji-31	198	30	suggest	suggest	VERB
aji-31	198	31	it	it	PRON
aji-31	198	32	alternativeness	alternativeness	NOUN
aji-31	198	33	to	to	AUX
aji-31	198	34	ia	ia	VERB
aji-31	198	35	steroid	steroid	NOUN
aji-31	199	1	[	[	X
aji-31	199	2	36	36	NUM
aji-31	199	3	]	]	PUNCT
aji-31	199	4	.	.	PUNCT
aji-31	200	1	7.3	7.3	NUM
aji-31	200	2	curcumin	curcumin	NOUN
aji-31	200	3	clinical	clinical	ADJ
aji-31	200	4	trials	trial	NOUN
aji-31	200	5	shows	show	VERB
aji-31	200	6	similar	similar	ADJ
aji-31	200	7	efficacy	efficacy	NOUN
aji-31	200	8	of	of	ADP
aji-31	200	9	curcuma	curcuma	PROPN
aji-31	200	10	formulation	formulation	NOUN
aji-31	200	11	with	with	ADP
aji-31	200	12	nsaids	nsaid	NOUN
aji-31	200	13	and	and	CCONJ
aji-31	200	14	glucosamine	glucosamine	NOUN
aji-31	200	15	for	for	ADP
aji-31	200	16	treatment	treatment	NOUN
aji-31	200	17	of	of	ADP
aji-31	200	18	osteoporosis	osteoporosis	NOUN
aji-31	200	19	[	[	X
aji-31	200	20	37	37	NUM
aji-31	200	21	]	]	PUNCT
aji-31	200	22	.	.	PUNCT
aji-31	201	1	a	a	DET
aji-31	201	2	multicenter	multicenter	ADJ
aji-31	201	3	study	study	NOUN
aji-31	201	4	reveal	reveal	VERB
aji-31	201	5	the	the	DET
aji-31	201	6	efficacy	efficacy	NOUN
aji-31	201	7	and	and	CCONJ
aji-31	201	8	safety	safety	NOUN
aji-31	201	9	of	of	ADP
aji-31	201	10	curcuma	curcuma	PROPN
aji-31	201	11	domestica	domestica	PROPN
aji-31	201	12	extracts	extract	NOUN
aji-31	201	13	in	in	ADP
aji-31	201	14	pain	pain	NOUN
aji-31	201	15	reduction	reduction	NOUN
aji-31	201	16	and	and	CCONJ
aji-31	201	17	functional	functional	ADJ
aji-31	201	18	improvement	improvement	NOUN
aji-31	201	19	and	and	CCONJ
aji-31	201	20	further	far	ADV
aji-31	201	21	shows	show	VERB
aji-31	201	22	it	it	PRON
aji-31	201	23	effectiveness	effectiveness	NOUN
aji-31	201	24	,	,	PUNCT
aji-31	201	25	similar	similar	ADJ
aji-31	201	26	to	to	ADP
aji-31	201	27	that	that	PRON
aji-31	201	28	of	of	ADP
aji-31	201	29	ibuprofen	ibuprofen	NOUN
aji-31	202	1	[	[	X
aji-31	202	2	38	38	NUM
aji-31	202	3	]	]	PUNCT
aji-31	202	4	.	.	PUNCT
aji-31	203	1	the	the	DET
aji-31	203	2	adjuvant	adjuvant	ADJ
aji-31	203	3	therapy	therapy	NOUN
aji-31	203	4	of	of	ADP
aji-31	203	5	curcumin	curcumin	NOUN
aji-31	203	6	with	with	ADP
aji-31	203	7	diclofenac	diclofenac	NOUN
aji-31	203	8	has	have	VERB
aji-31	203	9	more	more	ADJ
aji-31	203	10	potential	potential	ADJ
aji-31	203	11	and	and	CCONJ
aji-31	203	12	beneficial	beneficial	ADJ
aji-31	203	13	effect	effect	NOUN
aji-31	203	14	than	than	ADP
aji-31	203	15	individual	individual	ADJ
aji-31	203	16	effect	effect	NOUN
aji-31	203	17	of	of	ADP
aji-31	203	18	diclofenac	diclofenac	NOUN
aji-31	203	19	alone	alone	ADV
aji-31	203	20	[	[	X
aji-31	203	21	39	39	NUM
aji-31	203	22	]	]	PUNCT
aji-31	203	23	.	.	PUNCT
aji-31	204	1	a	a	DET
aji-31	204	2	randomized	randomized	ADJ
aji-31	204	3	,	,	PUNCT
aji-31	204	4	double	double	ADJ
aji-31	204	5	-	-	PUNCT
aji-31	204	6	blind	blind	ADJ
aji-31	204	7	,	,	PUNCT
aji-31	204	8	placebo	placebo	NOUN
aji-31	204	9	-	-	PUNCT
aji-31	204	10	controlled	control	VERB
aji-31	204	11	,	,	PUNCT
aji-31	204	12	prospective	prospective	ADJ
aji-31	204	13	clinical	clinical	ADJ
aji-31	204	14	study	study	NOUN
aji-31	204	15	of	of	ADP
aji-31	204	16	a	a	DET
aji-31	204	17	highly	highly	ADV
aji-31	204	18	bioavailable	bioavailable	ADJ
aji-31	204	19	form	form	NOUN
aji-31	204	20	of	of	ADP
aji-31	204	21	curcumin	curcumin	NOUN
aji-31	204	22	(	(	PUNCT
aji-31	204	23	theracurmin	theracurmin	NOUN
aji-31	204	24	)	)	PUNCT
aji-31	204	25	in	in	ADP
aji-31	204	26	patients	patient	NOUN
aji-31	204	27	with	with	ADP
aji-31	204	28	osteoarthritis	osteoarthritis	NOUN
aji-31	204	29	reveal	reveal	VERB
aji-31	204	30	significant	significant	ADJ
aji-31	204	31	effect	effect	NOUN
aji-31	204	32	of	of	ADP
aji-31	204	33	the	the	DET
aji-31	204	34	compound	compound	NOUN
aji-31	204	35	in	in	ADP
aji-31	204	36	deceasing	decease	VERB
aji-31	204	37	pain	pain	NOUN
aji-31	204	38	and	and	CCONJ
aji-31	204	39	its	its	PRON
aji-31	204	40	potential	potential	NOUN
aji-31	204	41	in	in	ADP
aji-31	204	42	the	the	DET
aji-31	204	43	treatment	treatment	NOUN
aji-31	204	44	of	of	ADP
aji-31	204	45	human	human	ADJ
aji-31	204	46	knee	knee	NOUN
aji-31	204	47	osteoarthritis	osteoarthritis	NOUN
aji-31	204	48	in	in	ADP
aji-31	204	49	the	the	DET
aji-31	204	50	future	future	NOUN
aji-31	204	51	[	[	X
aji-31	204	52	40	40	NUM
aji-31	204	53	]	]	PUNCT
aji-31	204	54	.	.	PUNCT
aji-31	205	1	meriva	meriva	PROPN
aji-31	205	2	(	(	PUNCT
aji-31	205	3	a	a	DET
aji-31	205	4	curcuminphosphatidylcholine	curcuminphosphatidylcholine	NOUN
aji-31	205	5	complex	complex	NOUN
aji-31	205	6	)	)	PUNCT
aji-31	205	7	is	be	AUX
aji-31	205	8	also	also	ADV
aji-31	205	9	referred	refer	VERB
aji-31	205	10	as	as	ADP
aji-31	205	11	effective	effective	ADJ
aji-31	205	12	and	and	CCONJ
aji-31	205	13	safe	safe	ADJ
aji-31	205	14	agent	agent	NOUN
aji-31	205	15	for	for	ADP
aji-31	205	16	the	the	DET
aji-31	205	17	complementary	complementary	ADJ
aji-31	205	18	management	management	NOUN
aji-31	205	19	of	of	ADP
aji-31	205	20	osteoarthritis	osteoarthritis	NOUN
aji-31	205	21	,	,	PUNCT
aji-31	205	22	leading	lead	VERB
aji-31	205	23	to	to	ADP
aji-31	205	24	better	well	ADJ
aji-31	205	25	disease	disease	NOUN
aji-31	205	26	control	control	NOUN
aji-31	205	27	,	,	PUNCT
aji-31	205	28	a	a	DET
aji-31	205	29	decreased	decrease	VERB
aji-31	205	30	use	use	NOUN
aji-31	205	31	of	of	ADP
aji-31	205	32	nsaids	nsaid	NOUN
aji-31	205	33	,	,	PUNCT
aji-31	205	34	and	and	CCONJ
aji-31	205	35	overall	overall	ADJ
aji-31	205	36	improvement	improvement	NOUN
aji-31	205	37	in	in	ADP
aji-31	205	38	the	the	DET
aji-31	205	39	quality	quality	NOUN
aji-31	205	40	of	of	ADP
aji-31	205	41	life	life	NOUN
aji-31	205	42	[	[	X
aji-31	205	43	41	41	NUM
aji-31	205	44	]	]	PUNCT
aji-31	205	45	.	.	PUNCT
aji-31	206	1	another	another	DET
aji-31	206	2	study	study	NOUN
aji-31	206	3	shows	show	VERB
aji-31	206	4	that	that	SCONJ
aji-31	206	5	formulation	formulation	NOUN
aji-31	206	6	of	of	ADP
aji-31	206	7	500	500	NUM
aji-31	206	8	mg	mg	PROPN
aji-31	206	9	curcuma	curcuma	PROPN
aji-31	206	10	longa	longa	PROPN
aji-31	206	11	and	and	CCONJ
aji-31	206	12	boswellia	boswellia	PROPN
aji-31	206	13	serrate	serrate	NOUN
aji-31	206	14	extract	extract	NOUN
aji-31	206	15	(	(	PUNCT
aji-31	206	16	cb	cb	NOUN
aji-31	206	17	)	)	PUNCT
aji-31	206	18	administered	administer	VERB
aji-31	206	19	twice	twice	ADV
aji-31	206	20	daily	daily	ADV
aji-31	206	21	demonstrated	demonstrate	VERB
aji-31	206	22	a	a	DET
aji-31	206	23	greater	great	ADJ
aji-31	206	24	improvement	improvement	NOUN
aji-31	206	25	in	in	ADP
aji-31	206	26	the	the	DET
aji-31	206	27	treatment	treatment	NOUN
aji-31	206	28	of	of	ADP
aji-31	206	29	oa	oa	PRON
aji-31	206	30	than	than	ADP
aji-31	206	31	100	100	NUM
aji-31	206	32	mg	mg	ADP
aji-31	206	33	of	of	ADP
aji-31	206	34	celecoxib	celecoxib	NOUN
aji-31	206	35	administered	administer	VERB
aji-31	206	36	twice	twice	DET
aji-31	206	37	a	a	DET
aji-31	206	38	day	day	NOUN
aji-31	206	39	in	in	ADP
aji-31	206	40	the	the	DET
aji-31	206	41	scores	score	NOUN
aji-31	206	42	for	for	ADP
aji-31	206	43	pain	pain	NOUN
aji-31	206	44	,	,	PUNCT
aji-31	206	45	walking	walk	VERB
aji-31	206	46	distance	distance	NOUN
aji-31	206	47	and	and	CCONJ
aji-31	206	48	joint	joint	ADJ
aji-31	206	49	line	line	NOUN
aji-31	206	50	tenderness	tenderness	NOUN
aji-31	206	51	.	.	PUNCT
aji-31	207	1	the	the	DET
aji-31	207	2	cb	cb	PROPN
aji-31	207	3	formulation	formulation	NOUN
aji-31	207	4	was	be	AUX
aji-31	207	5	equally	equally	ADV
aji-31	207	6	effective	effective	ADJ
aji-31	207	7	as	as	ADP
aji-31	207	8	celecoxib	celecoxib	NOUN
aji-31	207	9	in	in	ADP
aji-31	207	10	alleviating	alleviate	VERB
aji-31	207	11	crepitus	crepitus	NOUN
aji-31	207	12	,	,	PUNCT
aji-31	207	13	and	and	CCONJ
aji-31	207	14	increasing	increase	VERB
aji-31	207	15	the	the	DET
aji-31	207	16	range	range	NOUN
aji-31	207	17	of	of	ADP
aji-31	207	18	joint	joint	ADJ
aji-31	207	19	movements	movement	NOUN
aji-31	207	20	with	with	ADP
aji-31	207	21	no	no	DET
aji-31	207	22	dose	dose	NOUN
aji-31	207	23	-	-	PUNCT
aji-31	207	24	related	relate	VERB
aji-31	207	25	toxicity	toxicity	NOUN
aji-31	207	26	and	and	CCONJ
aji-31	207	27	ultimately	ultimately	ADV
aji-31	207	28	the	the	DET
aji-31	207	29	formulation	formulation	NOUN
aji-31	207	30	was	be	AUX
aji-31	207	31	termed	term	VERB
aji-31	207	32	superior	superior	ADJ
aji-31	207	33	to	to	PART
aji-31	207	34	celecoxib	celecoxib	VERB
aji-31	207	35	(	(	PUNCT
aji-31	207	36	nsaids	nsaids	PROPN
aji-31	207	37	)	)	PUNCT
aji-31	207	38	for	for	ADP
aji-31	207	39	the	the	DET
aji-31	207	40	treatment	treatment	NOUN
aji-31	207	41	of	of	ADP
aji-31	207	42	active	active	ADJ
aji-31	207	43	oa	oa	NOUN
aji-31	207	44	[	[	X
aji-31	207	45	42	42	NUM
aji-31	207	46	]	]	PUNCT
aji-31	207	47	.	.	PUNCT
aji-31	208	1	7.4	7.4	NUM
aji-31	208	2	bisphosphonates	bisphosphonate	NOUN
aji-31	208	3	bisphosphonates	bisphosphonate	NOUN
aji-31	208	4	are	be	AUX
aji-31	208	5	a	a	DET
aji-31	208	6	group	group	NOUN
aji-31	208	7	of	of	ADP
aji-31	208	8	medicines	medicine	NOUN
aji-31	208	9	that	that	PRON
aji-31	208	10	slow	slow	VERB
aji-31	208	11	down	down	ADP
aji-31	208	12	or	or	CCONJ
aji-31	208	13	prevent	prevent	VERB
aji-31	208	14	bone	bone	NOUN
aji-31	208	15	loss	loss	NOUN
aji-31	208	16	,	,	PUNCT
aji-31	208	17	strengthening	strengthen	VERB
aji-31	208	18	bones	bone	NOUN
aji-31	208	19	.	.	PUNCT
aji-31	209	1	they	they	PRON
aji-31	209	2	work	work	VERB
aji-31	209	3	by	by	ADP
aji-31	209	4	inhibiting	inhibit	VERB
aji-31	209	5	osteoclasts	osteoclast	NOUN
aji-31	209	6	which	which	PRON
aji-31	209	7	are	be	AUX
aji-31	209	8	responsible	responsible	ADJ
aji-31	209	9	for	for	ADP
aji-31	209	10	breaking	break	VERB
aji-31	209	11	down	down	ADP
aji-31	209	12	and	and	CCONJ
aji-31	209	13	reabsorbing	reabsorb	VERB
aji-31	209	14	minerals	mineral	NOUN
aji-31	209	15	such	such	ADJ
aji-31	209	16	as	as	ADP
aji-31	209	17	calcium	calcium	NOUN
aji-31	209	18	from	from	ADP
aji-31	209	19	bone	bone	NOUN
aji-31	209	20	.	.	PUNCT
aji-31	210	1	meta	meta	ADJ
aji-31	210	2	-	-	PUNCT
aji-31	210	3	analysis	analysis	NOUN
aji-31	210	4	showed	show	VERB
aji-31	210	5	that	that	SCONJ
aji-31	210	6	bisphosphonates	bisphosphonate	NOUN
aji-31	210	7	therapy	therapy	NOUN
aji-31	210	8	is	be	AUX
aji-31	210	9	effective	effective	ADJ
aji-31	210	10	in	in	ADP
aji-31	210	11	relieving	relieve	VERB
aji-31	210	12	pain	pain	NOUN
aji-31	210	13	and	and	CCONJ
aji-31	210	14	accelerating	accelerate	VERB
aji-31	210	15	functional	functional	ADJ
aji-31	210	16	recovery	recovery	NOUN
aji-31	210	17	for	for	ADP
aji-31	210	18	patients	patient	NOUN
aji-31	210	19	with	with	ADP
aji-31	210	20	oa	oa	PROPN
aji-31	211	1	[	[	X
aji-31	211	2	43	43	NUM
aji-31	211	3	]	]	PUNCT
aji-31	211	4	.	.	PUNCT
aji-31	212	1	in	in	ADP
aji-31	212	2	another	another	DET
aji-31	212	3	clinical	clinical	ADJ
aji-31	212	4	studies	study	NOUN
aji-31	212	5	,	,	PUNCT
aji-31	212	6	administering	administer	VERB
aji-31	212	7	alendronate	alendronate	NOUN
aji-31	212	8	sodium	sodium	NOUN
aji-31	212	9	(	(	PUNCT
aji-31	212	10	a	a	DET
aji-31	212	11	bisphosphonate	bisphosphonate	NOUN
aji-31	212	12	drug	drug	NOUN
aji-31	212	13	)	)	PUNCT
aji-31	212	14	for	for	ADP
aji-31	212	15	patients	patient	NOUN
aji-31	212	16	with	with	ADP
aji-31	212	17	oa	oa	PROPN
aji-31	212	18	has	have	VERB
aji-31	212	19	clinical	clinical	ADJ
aji-31	212	20	efficacy	efficacy	NOUN
aji-31	212	21	in	in	ADP
aji-31	212	22	reducing	reduce	VERB
aji-31	212	23	joint	joint	ADJ
aji-31	212	24	complications	complication	NOUN
aji-31	212	25	with	with	ADP
aji-31	212	26	significant	significant	ADJ
aji-31	212	27	structural	structural	ADJ
aji-31	212	28	improvement	improvement	NOUN
aji-31	212	29	of	of	ADP
aji-31	212	30	the	the	DET
aji-31	212	31	joints	joint	NOUN
aji-31	212	32	,	,	PUNCT
aji-31	212	33	and	and	CCONJ
aji-31	212	34	may	may	AUX
aji-31	212	35	delay	delay	VERB
aji-31	212	36	and	and	CCONJ
aji-31	212	37	prevent	prevent	VERB
aji-31	212	38	further	further	ADJ
aji-31	212	39	disease	disease	NOUN
aji-31	212	40	progression	progression	NOUN
aji-31	212	41	probably	probably	ADV
aji-31	212	42	through	through	ADP
aji-31	212	43	inhibition	inhibition	NOUN
aji-31	212	44	of	of	ADP
aji-31	212	45	leptin	leptin	NOUN
aji-31	212	46	activity	activity	NOUN
aji-31	212	47	[	[	X
aji-31	212	48	44	44	NUM
aji-31	212	49	]	]	PUNCT
aji-31	212	50	.	.	PUNCT
aji-31	213	1	risedronate	risedronate	VERB
aji-31	213	2	a	a	DET
aji-31	213	3	bisphosphonate	bisphosphonate	NOUN
aji-31	213	4	drug	drug	NOUN
aji-31	213	5	in	in	ADP
aji-31	213	6	comparison	comparison	NOUN
aji-31	213	7	with	with	ADP
aji-31	213	8	placebo	placebo	NOUN
aji-31	213	9	did	do	AUX
aji-31	213	10	not	not	PART
aji-31	213	11	improve	improve	VERB
aji-31	213	12	signs	sign	NOUN
aji-31	213	13	or	or	CCONJ
aji-31	213	14	symptoms	symptom	NOUN
aji-31	213	15	of	of	ADP
aji-31	213	16	oa	oa	NOUN
aji-31	213	17	,	,	PUNCT
aji-31	213	18	nor	nor	CCONJ
aji-31	213	19	did	do	AUX
aji-31	213	20	it	it	PRON
aji-31	213	21	alter	alter	VERB
aji-31	213	22	progression	progression	NOUN
aji-31	213	23	of	of	ADP
aji-31	213	24	oa	oa	NOUN
aji-31	213	25	,	,	PUNCT
aji-31	213	26	only	only	ADJ
aji-31	213	27	reduction	reduction	NOUN
aji-31	213	28	in	in	ADP
aji-31	213	29	the	the	DET
aji-31	213	30	level	level	NOUN
aji-31	213	31	of	of	ADP
aji-31	213	32	marker	marker	NOUN
aji-31	213	33	of	of	ADP
aji-31	213	34	cartilage	cartilage	NOUN
aji-31	213	35	degradation	degradation	NOUN
aji-31	213	36	was	be	AUX
aji-31	213	37	observed	observe	VERB
aji-31	213	38	however	however	ADV
aji-31	213	39	sustained	sustain	VERB
aji-31	213	40	clinically	clinically	ADV
aji-31	213	41	relevant	relevant	ADJ
aji-31	213	42	improvement	improvement	NOUN
aji-31	213	43	in	in	ADP
aji-31	213	44	signs	sign	NOUN
aji-31	213	45	and	and	CCONJ
aji-31	213	46	symptoms	symptom	NOUN
aji-31	213	47	was	be	AUX
aji-31	213	48	observed	observe	VERB
aji-31	213	49	in	in	ADP
aji-31	213	50	all	all	DET
aji-31	213	51	treatment	treatment	NOUN
aji-31	213	52	and	and	CCONJ
aji-31	213	53	placebo	placebo	NOUN
aji-31	213	54	groups	group	NOUN
aji-31	213	55	[	[	X
aji-31	213	56	45	45	NUM
aji-31	213	57	]	]	PUNCT
aji-31	213	58	.	.	PUNCT
aji-31	214	1	in	in	ADP
aji-31	214	2	a	a	DET
aji-31	214	3	one	one	NUM
aji-31	214	4	-	-	PUNCT
aji-31	214	5	year	year	NOUN
aji-31	214	6	,	,	PUNCT
aji-31	214	7	placebocontrolled	placebocontrolle	VERB
aji-31	214	8	trial	trial	NOUN
aji-31	214	9	that	that	PRON
aji-31	214	10	included	include	VERB
aji-31	214	11	59	59	NUM
aji-31	214	12	patients	patient	NOUN
aji-31	214	13	with	with	ADP
aji-31	214	14	knee	knee	NOUN
aji-31	214	15	oa	oa	PROPN
aji-31	214	16	treated	treat	VERB
aji-31	214	17	with	with	ADP
aji-31	214	18	zoledronic	zoledronic	ADJ
aji-31	214	19	acid	acid	NOUN
aji-31	214	20	5	5	NUM
aji-31	214	21	mg	mg	ADV
aji-31	214	22	intravenously	intravenously	ADV
aji-31	214	23	as	as	ADP
aji-31	214	24	a	a	DET
aji-31	214	25	single	single	ADJ
aji-31	214	26	infusion	infusion	NOUN
aji-31	214	27	,	,	PUNCT
aji-31	214	28	a	a	DET
aji-31	214	29	significant	significant	ADJ
aji-31	214	30	reduction	reduction	NOUN
aji-31	214	31	in	in	ADP
aji-31	214	32	visual	visual	ADJ
aji-31	214	33	analogue	analogue	NOUN
aji-31	214	34	pain	pain	NOUN
aji-31	214	35	scores	score	NOUN
aji-31	214	36	versus	versus	ADP
aji-31	214	37	placebo	placebo	NOUN
aji-31	214	38	was	be	AUX
aji-31	214	39	seen	see	VERB
aji-31	214	40	after	after	ADP
aji-31	214	41	six	six	NUM
aji-31	214	42	months	month	NOUN
aji-31	214	43	[	[	X
aji-31	214	44	46	46	NUM
aji-31	214	45	]	]	SYM
aji-31	214	46	.	.	PUNCT
aji-31	215	1	7.5	7.5	NUM
aji-31	215	2	strontium	strontium	NOUN
aji-31	215	3	ranelate	ranelate	NOUN
aji-31	215	4	strontium	strontium	NOUN
aji-31	215	5	ranelate	ranelate	NOUN
aji-31	215	6	(	(	PUNCT
aji-31	215	7	sr	sr	PROPN
aji-31	215	8	)	)	PUNCT
aji-31	215	9	is	be	AUX
aji-31	215	10	an	an	DET
aji-31	215	11	anti	anti	ADJ
aji-31	215	12	-	-	ADJ
aji-31	215	13	osteoporotic	osteoporotic	ADJ
aji-31	215	14	drug	drug	NOUN
aji-31	215	15	responsible	responsible	ADJ
aji-31	215	16	for	for	ADP
aji-31	215	17	balance	balance	NOUN
aji-31	215	18	between	between	ADP
aji-31	215	19	bone	bone	NOUN
aji-31	215	20	resorption	resorption	NOUN
aji-31	215	21	and	and	CCONJ
aji-31	215	22	bone	bone	NOUN
aji-31	215	23	formation	formation	NOUN
aji-31	215	24	[	[	X
aji-31	215	25	47	47	NUM
aji-31	215	26	]	]	PUNCT
aji-31	215	27	.	.	PUNCT
aji-31	216	1	clinical	clinical	ADJ
aji-31	216	2	trial	trial	NOUN
aji-31	216	3	reveals	reveal	VERB
aji-31	216	4	that	that	SCONJ
aji-31	216	5	treatment	treatment	NOUN
aji-31	216	6	with	with	ADP
aji-31	216	7	1	1	NUM
aji-31	216	8	or	or	CCONJ
aji-31	216	9	2	2	NUM
aji-31	216	10	g	g	NOUN
aji-31	216	11	of	of	ADP
aji-31	216	12	strontium	strontium	NOUN
aji-31	216	13	ranelate	ranelate	NOUN
aji-31	216	14	per	per	ADP
aji-31	216	15	day	day	NOUN
aji-31	216	16	is	be	AUX
aji-31	216	17	associated	associate	VERB
aji-31	216	18	with	with	ADP
aji-31	216	19	significant	significant	ADJ
aji-31	216	20	structural	structural	ADJ
aji-31	216	21	changes	change	NOUN
aji-31	216	22	in	in	ADP
aji-31	216	23	patients	patient	NOUN
aji-31	216	24	with	with	ADP
aji-31	216	25	knee	knee	NOUN
aji-31	216	26	osteoarthritis	osteoarthritis	NOUN
aji-31	216	27	;	;	PUNCT
aji-31	216	28	furthermore	furthermore	ADV
aji-31	216	29	,	,	PUNCT
aji-31	216	30	there	there	PRON
aji-31	216	31	is	be	VERB
aji-31	216	32	a	a	DET
aji-31	216	33	beneficial	beneficial	ADJ
aji-31	216	34	effect	effect	NOUN
aji-31	216	35	on	on	ADP
aji-31	216	36	the	the	DET
aji-31	216	37	symptoms	symptom	NOUN
aji-31	216	38	specifically	specifically	ADV
aji-31	216	39	at	at	ADP
aji-31	216	40	dosage	dosage	NOUN
aji-31	216	41	of	of	ADP
aji-31	216	42	2	2	NUM
aji-31	216	43	g	g	NOUN
aji-31	216	44	/	/	SYM
aji-31	216	45	day	day	NOUN
aji-31	216	46	[	[	X
aji-31	216	47	48	48	NUM
aji-31	216	48	]	]	PUNCT
aji-31	216	49	.	.	PUNCT
aji-31	217	1	another	another	DET
aji-31	217	2	study	study	NOUN
aji-31	217	3	shows	show	VERB
aji-31	217	4	that	that	SCONJ
aji-31	217	5	dose	dose	NOUN
aji-31	217	6	of	of	ADP
aji-31	217	7	1800	1800	NUM
aji-31	217	8	mg	mg	PROPN
aji-31	217	9	/	/	SYM
aji-31	217	10	kg	kg	PROPN
aji-31	217	11	/	/	SYM
aji-31	217	12	day	day	NOUN
aji-31	217	13	of	of	ADP
aji-31	217	14	sr	sr	PROPN
aji-31	217	15	significantly	significantly	ADV
aji-31	217	16	attenuated	attenuate	VERB
aji-31	217	17	shehu	shehu	NOUN
aji-31	217	18	et	et	PROPN
aji-31	217	19	al	al	PROPN
aji-31	217	20	.	.	PROPN
aji-31	217	21	;	;	PUNCT
aji-31	217	22	aji	aji	PROPN
aji-31	217	23	,	,	PUNCT
aji-31	217	24	3(1	3(1	NUM
aji-31	217	25	):	):	PUNCT
aji-31	217	26	223	223	NUM
aji-31	217	27	-	-	SYM
aji-31	217	28	232	232	NUM
aji-31	217	29	,	,	PUNCT
aji-31	217	30	2020	2020	NUM
aji-31	217	31	;	;	PUNCT
aji-31	217	32	article	article	NOUN
aji-31	217	33	no.aji.57637	no.aji.57637	ADJ
aji-31	217	34	229	229	NUM
aji-31	217	35	cartilage	cartilage	NOUN
aji-31	217	36	matrix	matrix	NOUN
aji-31	217	37	and	and	CCONJ
aji-31	217	38	chondrocyte	chondrocyte	NOUN
aji-31	217	39	loss	loss	NOUN
aji-31	217	40	,	,	PUNCT
aji-31	217	41	and	and	CCONJ
aji-31	217	42	decreased	decrease	VERB
aji-31	217	43	chondrocyte	chondrocyte	NOUN
aji-31	217	44	apoptosis	apoptosis	NOUN
aji-31	217	45	,	,	PUNCT
aji-31	217	46	in	in	ADP
aji-31	217	47	a	a	DET
aji-31	217	48	medial	medial	ADJ
aji-31	217	49	meniscal	meniscal	ADJ
aji-31	217	50	tear	tear	NOUN
aji-31	217	51	model	model	NOUN
aji-31	217	52	using	use	VERB
aji-31	217	53	sprague	sprague	NOUN
aji-31	217	54	–	–	PUNCT
aji-31	217	55	dawley	dawley	NOUN
aji-31	217	56	rats	rat	NOUN
aji-31	217	57	[	[	X
aji-31	217	58	49	49	NUM
aji-31	217	59	]	]	PUNCT
aji-31	217	60	.	.	PUNCT
aji-31	218	1	7.6	7.6	NUM
aji-31	218	2	chondroitin	chondroitin	NOUN
aji-31	218	3	sulfate	sulfate	NOUN
aji-31	218	4	a	a	DET
aji-31	218	5	1	1	NUM
aji-31	218	6	year	year	NOUN
aji-31	218	7	,	,	PUNCT
aji-31	218	8	randomized	randomize	VERB
aji-31	218	9	,	,	PUNCT
aji-31	218	10	double	double	ADJ
aji-31	218	11	-	-	PUNCT
aji-31	218	12	blind	blind	ADJ
aji-31	218	13	,	,	PUNCT
aji-31	218	14	multicenter	multicenter	ADJ
aji-31	218	15	clinical	clinical	ADJ
aji-31	218	16	study	study	NOUN
aji-31	218	17	in	in	ADP
aji-31	218	18	japan	japan	PROPN
aji-31	218	19	,	,	PUNCT
aji-31	218	20	shows	show	VERB
aji-31	218	21	that	that	SCONJ
aji-31	218	22	treatment	treatment	NOUN
aji-31	218	23	with	with	ADP
aji-31	218	24	sodium	sodium	NOUN
aji-31	218	25	chondroitin	chondroitin	NOUN
aji-31	218	26	sulfate	sulfate	NOUN
aji-31	218	27	at	at	ADP
aji-31	218	28	a	a	DET
aji-31	218	29	dose	dose	NOUN
aji-31	218	30	 	 	SPACE
aji-31	218	31	of	of	ADP
aji-31	218	32	 	 	SPACE
aji-31	218	33	1560	1560	NUM
aji-31	218	34	 	 	SPACE
aji-31	218	35	mg	mg	PROPN
aji-31	218	36	/	/	SYM
aji-31	218	37	d	d	NOUN
aji-31	218	38	 	 	SPACE
aji-31	218	39	is	be	AUX
aji-31	218	40	 	 	SPACE
aji-31	218	41	more	more	ADV
aji-31	218	42	 	 	SPACE
aji-31	218	43	effective	effective	ADJ
aji-31	218	44	  	  	SPACE
aji-31	218	45	than	than	ADP
aji-31	218	46	260	260	NUM
aji-31	218	47	mg	mg	NOUN
aji-31	218	48	/	/	SYM
aji-31	218	49	d	d	NOUN
aji-31	218	50	more	more	ADJ
aji-31	218	51	resultant	resultant	NOUN
aji-31	218	52	to	to	ADP
aji-31	218	53	pain	pain	NOUN
aji-31	218	54	relief	relief	NOUN
aji-31	218	55	in	in	ADP
aji-31	218	56	patients	patient	NOUN
aji-31	218	57	with	with	ADP
aji-31	218	58	knee	knee	NOUN
aji-31	218	59	oa	oa	X
aji-31	219	1	[	[	X
aji-31	219	2	50	50	NUM
aji-31	219	3	]	]	PUNCT
aji-31	219	4	.	.	PUNCT
aji-31	220	1	however	however	ADV
aji-31	220	2	,	,	PUNCT
aji-31	220	3	a	a	DET
aji-31	220	4	2	2	NUM
aji-31	220	5	-	-	PUNCT
aji-31	220	6	year	year	NOUN
aji-31	220	7	multicentre	multicentre	NOUN
aji-31	220	8	exploratory	exploratory	ADJ
aji-31	220	9	study	study	NOUN
aji-31	220	10	on	on	ADP
aji-31	220	11	efficacy	efficacy	NOUN
aji-31	220	12	of	of	ADP
aji-31	220	13	chondroitin	chondroitin	NOUN
aji-31	220	14	sulfate	sulfate	NOUN
aji-31	220	15	versus	versus	ADP
aji-31	220	16	celecoxib	celecoxib	NOUN
aji-31	220	17	on	on	ADP
aji-31	220	18	knee	knee	NOUN
aji-31	220	19	osteoarthritis	osteoarthritis	NOUN
aji-31	220	20	structural	structural	ADJ
aji-31	220	21	changes	change	NOUN
aji-31	220	22	concluded	conclude	VERB
aji-31	220	23	that	that	SCONJ
aji-31	220	24	chondroitin	chondroitin	NOUN
aji-31	220	25	sulphate	sulphate	NOUN
aji-31	220	26	is	be	AUX
aji-31	220	27	more	more	ADV
aji-31	220	28	superior	superior	ADJ
aji-31	220	29	over	over	ADP
aji-31	220	30	celecoxib	celecoxib	NOUN
aji-31	220	31	at	at	ADP
aji-31	220	32	reducing	reduce	VERB
aji-31	220	33	cartilage	cartilage	NOUN
aji-31	220	34	volume	volume	NOUN
aji-31	220	35	loss	loss	NOUN
aji-31	220	36	in	in	ADP
aji-31	220	37	knee	knee	NOUN
aji-31	221	1	oa	oa	NUM
aji-31	221	2	patients	patient	NOUN
aji-31	221	3	[	[	X
aji-31	221	4	51	51	NUM
aji-31	221	5	]	]	PUNCT
aji-31	221	6	.	.	PUNCT
aji-31	222	1	meta	meta	VERB
aji-31	222	2	-	-	PUNCT
aji-31	222	3	analysis	analysis	NOUN
aji-31	222	4	of	of	ADP
aji-31	222	5	randomized	randomized	ADJ
aji-31	222	6	controlled	control	VERB
aji-31	222	7	trials	trial	NOUN
aji-31	222	8	demonstrated	demonstrate	VERB
aji-31	222	9	that	that	SCONJ
aji-31	222	10	oral	oral	ADJ
aji-31	222	11	chondroitin	chondroitin	NOUN
aji-31	222	12	is	be	AUX
aji-31	222	13	more	more	ADV
aji-31	222	14	effective	effective	ADJ
aji-31	222	15	than	than	ADP
aji-31	222	16	placebo	placebo	NOUN
aji-31	222	17	on	on	ADP
aji-31	222	18	relieving	relieve	VERB
aji-31	222	19	pain	pain	NOUN
aji-31	222	20	and	and	CCONJ
aji-31	222	21	improving	improve	VERB
aji-31	222	22	physical	physical	ADJ
aji-31	222	23	function	function	NOUN
aji-31	222	24	.	.	PUNCT
aji-31	223	1	although	although	SCONJ
aji-31	223	2	glucosamine	glucosamine	NOUN
aji-31	223	3	showed	show	VERB
aji-31	223	4	positive	positive	ADJ
aji-31	223	5	effect	effect	NOUN
aji-31	223	6	on	on	ADP
aji-31	223	7	stiffness	stiffness	ADJ
aji-31	223	8	outcome	outcome	NOUN
aji-31	223	9	,	,	PUNCT
aji-31	223	10	further	further	ADJ
aji-31	223	11	studies	study	NOUN
aji-31	223	12	are	be	AUX
aji-31	223	13	requested	request	VERB
aji-31	223	14	to	to	PART
aji-31	223	15	investigate	investigate	VERB
aji-31	223	16	the	the	DET
aji-31	223	17	accurate	accurate	ADJ
aji-31	223	18	effectiveness	effectiveness	NOUN
aji-31	223	19	of	of	ADP
aji-31	223	20	both	both	CCONJ
aji-31	223	21	the	the	DET
aji-31	223	22	two	two	NUM
aji-31	223	23	drugs	drug	NOUN
aji-31	223	24	[	[	X
aji-31	223	25	52	52	NUM
aji-31	223	26	]	]	PUNCT
aji-31	223	27	.	.	PUNCT
aji-31	224	1	7.7	7.7	NUM
aji-31	224	2	intra	intra	ADJ
aji-31	224	3	articular	articular	ADJ
aji-31	224	4	hyaluronic	hyaluronic	ADJ
aji-31	224	5	acids	acid	NOUN
aji-31	224	6	a	a	DET
aji-31	224	7	canadian	canadian	ADJ
aji-31	224	8	evidence	evidence	NOUN
aji-31	224	9	-	-	PUNCT
aji-31	224	10	based	base	VERB
aji-31	224	11	perspective	perspective	NOUN
aji-31	224	12	demonstrated	demonstrate	VERB
aji-31	224	13	that	that	SCONJ
aji-31	224	14	treatment	treatment	NOUN
aji-31	224	15	with	with	ADP
aji-31	224	16	intra	intra	ADJ
aji-31	224	17	articular	articular	ADJ
aji-31	224	18	hyaluronic	hyaluronic	ADJ
aji-31	224	19	acids	acid	NOUN
aji-31	224	20	is	be	AUX
aji-31	224	21	well	well	ADV
aji-31	224	22	tolerated	tolerate	VERB
aji-31	224	23	,	,	PUNCT
aji-31	224	24	with	with	ADP
aji-31	224	25	significantly	significantly	ADV
aji-31	224	26	improved	improve	VERB
aji-31	224	27	pain	pain	NOUN
aji-31	224	28	,	,	PUNCT
aji-31	224	29	function	function	NOUN
aji-31	224	30	and	and	CCONJ
aji-31	224	31	stiffness	stiffness	ADJ
aji-31	224	32	outcomes	outcome	NOUN
aji-31	224	33	compared	compare	VERB
aji-31	224	34	with	with	ADP
aji-31	224	35	placebo	placebo	NOUN
aji-31	224	36	or	or	CCONJ
aji-31	224	37	noninterventional	noninterventional	ADJ
aji-31	224	38	controls	control	NOUN
aji-31	224	39	in	in	ADP
aji-31	224	40	patients	patient	NOUN
aji-31	224	41	with	with	ADP
aji-31	224	42	mildto	mildto	PROPN
aji-31	224	43	-	-	PUNCT
aji-31	224	44	moderate	moderate	ADJ
aji-31	224	45	knee	knee	NOUN
aji-31	224	46	oa	oa	X
aji-31	225	1	[	[	X
aji-31	225	2	53	53	NUM
aji-31	225	3	]	]	PUNCT
aji-31	225	4	.	.	PUNCT
aji-31	226	1	multi	multi	ADJ
aji-31	226	2	-	-	ADJ
aji-31	226	3	center	center	ADJ
aji-31	226	4	open	open	ADJ
aji-31	226	5	perspective	perspective	NOUN
aji-31	226	6	study	study	NOUN
aji-31	226	7	suggests	suggest	VERB
aji-31	226	8	the	the	DET
aji-31	226	9	clinical	clinical	ADJ
aji-31	226	10	efficacy	efficacy	NOUN
aji-31	226	11	of	of	ADP
aji-31	226	12	a	a	DET
aji-31	226	13	single	single	ADJ
aji-31	226	14	intra	intra	ADJ
aji-31	226	15	-	-	ADJ
aji-31	226	16	articular	articular	ADJ
aji-31	226	17	injection	injection	NOUN
aji-31	226	18	of	of	ADP
aji-31	226	19	3	3	NUM
aji-31	226	20	ml	ml	NOUN
aji-31	226	21	intraarticular	intraarticular	ADJ
aji-31	226	22	hyaluronic	hyaluronic	ADJ
aji-31	226	23	acid	acid	NOUN
aji-31	226	24	solution	solution	NOUN
aji-31	226	25	containing	contain	VERB
aji-31	226	26	75	75	NUM
aji-31	226	27	mg	mg	ADV
aji-31	226	28	high	high	ADJ
aji-31	226	29	molecular	molecular	ADJ
aji-31	226	30	weight	weight	NOUN
aji-31	226	31	(	(	PUNCT
aji-31	226	32	>	>	SYM
aji-31	226	33	2	2	NUM
aji-31	226	34	mda	mda	PROPN
aji-31	226	35	)	)	PUNCT
aji-31	226	36	native	native	ADJ
aji-31	226	37	hyaluronic	hyaluronic	ADJ
aji-31	226	38	acid	acid	NOUN
aji-31	226	39	[	[	X
aji-31	226	40	54	54	NUM
aji-31	226	41	]	]	PUNCT
aji-31	226	42	.	.	PUNCT
aji-31	227	1	7.8	7.8	NUM
aji-31	227	2	glucosamine	glucosamine	NOUN
aji-31	227	3	sulfate	sulfate	NOUN
aji-31	227	4	evidence	evidence	NOUN
aji-31	227	5	from	from	ADP
aji-31	227	6	a	a	DET
aji-31	227	7	real	real	ADJ
aji-31	227	8	life	life	NOUN
aji-31	227	9	setting	set	VERB
aji-31	227	10	trials	trial	NOUN
aji-31	227	11	and	and	CCONJ
aji-31	227	12	surveys	survey	NOUN
aji-31	227	13	shows	show	VERB
aji-31	227	14	that	that	SCONJ
aji-31	227	15	different	different	ADJ
aji-31	227	16	therapeutic	therapeutic	ADJ
aji-31	227	17	effect	effect	NOUN
aji-31	227	18	are	be	AUX
aji-31	227	19	obtained	obtain	VERB
aji-31	227	20	with	with	ADP
aji-31	227	21	different	different	ADJ
aji-31	227	22	formulation	formulation	NOUN
aji-31	227	23	of	of	ADP
aji-31	227	24	glucosamine	glucosamine	NOUN
aji-31	227	25	.	.	PUNCT
aji-31	228	1	therefore	therefore	ADV
aji-31	228	2	,	,	PUNCT
aji-31	228	3	not	not	PART
aji-31	228	4	all	all	DET
aji-31	228	5	formulation	formulation	NOUN
aji-31	228	6	of	of	ADP
aji-31	228	7	glucosamine	glucosamine	NOUN
aji-31	228	8	should	should	AUX
aji-31	228	9	be	be	AUX
aji-31	228	10	afforded	afford	VERB
aji-31	228	11	same	same	ADJ
aji-31	228	12	level	level	NOUN
aji-31	228	13	of	of	ADP
aji-31	228	14	recommendation	recommendation	NOUN
aji-31	228	15	[	[	X
aji-31	228	16	55	55	NUM
aji-31	228	17	]	]	PUNCT
aji-31	228	18	.	.	PUNCT
aji-31	229	1	glucosamine	glucosamine	NOUN
aji-31	229	2	supplements	supplement	NOUN
aji-31	229	3	composed	compose	VERB
aji-31	229	4	of	of	ADP
aji-31	229	5	different	different	ADJ
aji-31	229	6	chemical	chemical	NOUN
aji-31	229	7	components	component	NOUN
aji-31	229	8	and	and	CCONJ
aji-31	229	9	have	have	AUX
aji-31	229	10	become	become	VERB
aji-31	229	11	a	a	DET
aji-31	229	12	mainstay	mainstay	NOUN
aji-31	229	13	in	in	ADP
aji-31	229	14	management	management	NOUN
aji-31	229	15	of	of	ADP
aji-31	229	16	oa	oa	PRON
aji-31	229	17	due	due	ADP
aji-31	229	18	to	to	ADP
aji-31	229	19	their	their	PRON
aji-31	229	20	symptom	symptom	NOUN
aji-31	229	21	-	-	PUNCT
aji-31	229	22	relieving	relieve	VERB
aji-31	229	23	effects	effect	NOUN
aji-31	229	24	,	,	PUNCT
aji-31	229	25	cost	cost	NOUN
aji-31	229	26	effectiveness	effectiveness	NOUN
aji-31	229	27	,	,	PUNCT
aji-31	229	28	important	important	ADJ
aji-31	229	29	structure	structure	NOUN
aji-31	229	30	-	-	PUNCT
aji-31	229	31	preserving	preserve	VERB
aji-31	229	32	and	and	CCONJ
aji-31	229	33	relatively	relatively	ADV
aji-31	229	34	non	non	ADJ
aji-31	229	35	-	-	ADJ
aji-31	229	36	toxic	toxic	ADJ
aji-31	229	37	adverse	adverse	ADJ
aji-31	229	38	effect	effect	NOUN
aji-31	229	39	profiles	profile	NOUN
aji-31	229	40	.	.	PUNCT
aji-31	230	1	however	however	ADV
aji-31	230	2	,	,	PUNCT
aji-31	230	3	researches	research	NOUN
aji-31	230	4	are	be	AUX
aji-31	230	5	required	require	VERB
aji-31	230	6	to	to	PART
aji-31	230	7	fully	fully	ADV
aji-31	230	8	understand	understand	VERB
aji-31	230	9	the	the	DET
aji-31	230	10	concept	concept	NOUN
aji-31	230	11	[	[	X
aji-31	230	12	56	56	NUM
aji-31	230	13	]	]	PUNCT
aji-31	230	14	.	.	PUNCT
aji-31	231	1	8	8	X
aji-31	231	2	.	.	X
aji-31	231	3	conclusion	conclusion	VERB
aji-31	231	4	many	many	ADJ
aji-31	231	5	studies	study	NOUN
aji-31	231	6	on	on	ADP
aji-31	231	7	osteoarthritis	osteoarthritis	NOUN
aji-31	231	8	gave	give	VERB
aji-31	231	9	more	more	ADJ
aji-31	231	10	insight	insight	NOUN
aji-31	231	11	on	on	ADP
aji-31	231	12	the	the	DET
aji-31	231	13	inflammatory	inflammatory	ADJ
aji-31	231	14	processes	process	NOUN
aji-31	231	15	,	,	PUNCT
aji-31	231	16	biochemical	biochemical	ADJ
aji-31	231	17	changes	change	NOUN
aji-31	231	18	and	and	CCONJ
aji-31	231	19	abnormalities	abnormality	NOUN
aji-31	231	20	in	in	ADP
aji-31	231	21	some	some	PRON
aji-31	231	22	of	of	ADP
aji-31	231	23	the	the	DET
aji-31	231	24	component	component	NOUN
aji-31	231	25	of	of	ADP
aji-31	231	26	healthy	healthy	ADJ
aji-31	231	27	joint	joint	NOUN
aji-31	231	28	.	.	PUNCT
aji-31	232	1	in	in	ADP
aji-31	232	2	this	this	DET
aji-31	232	3	review	review	NOUN
aji-31	232	4	we	we	PRON
aji-31	232	5	have	have	AUX
aji-31	232	6	highlighted	highlight	VERB
aji-31	232	7	clinical	clinical	ADJ
aji-31	232	8	efficacy	efficacy	NOUN
aji-31	232	9	and	and	CCONJ
aji-31	232	10	safety	safety	NOUN
aji-31	232	11	of	of	ADP
aji-31	232	12	some	some	DET
aji-31	232	13	therapeutics	therapeutic	NOUN
aji-31	232	14	used	use	VERB
aji-31	232	15	in	in	ADP
aji-31	232	16	the	the	DET
aji-31	232	17	treatment	treatment	NOUN
aji-31	232	18	of	of	ADP
aji-31	232	19	oa	oa	INTJ
aji-31	232	20	.	.	PUNCT
aji-31	233	1	however	however	ADV
aji-31	233	2	,	,	PUNCT
aji-31	233	3	extensive	extensive	ADJ
aji-31	233	4	clinical	clinical	ADJ
aji-31	233	5	trials	trial	NOUN
aji-31	233	6	should	should	AUX
aji-31	233	7	be	be	AUX
aji-31	233	8	taken	take	VERB
aji-31	233	9	to	to	PART
aji-31	233	10	critically	critically	ADV
aji-31	233	11	elucidate	elucidate	VERB
aji-31	233	12	the	the	DET
aji-31	233	13	efficacy	efficacy	NOUN
aji-31	233	14	of	of	ADP
aji-31	233	15	the	the	DET
aji-31	233	16	therapeutics	therapeutic	NOUN
aji-31	233	17	.	.	PUNCT
aji-31	234	1	consent	consent	NOUN
aji-31	234	2	it	it	PRON
aji-31	234	3	is	be	AUX
aji-31	234	4	not	not	PART
aji-31	234	5	applicable	applicable	ADJ
aji-31	234	6	.	.	PUNCT
aji-31	235	1	ethical	ethical	ADJ
aji-31	235	2	approval	approval	NOUN
aji-31	235	3	it	it	PRON
aji-31	235	4	is	be	AUX
aji-31	235	5	not	not	PART
aji-31	235	6	applicable	applicable	ADJ
aji-31	235	7	.	.	PUNCT
aji-31	236	1	acknowledgements	acknowledgement	NOUN
aji-31	236	2	we	we	PRON
aji-31	236	3	appreciate	appreciate	VERB
aji-31	236	4	the	the	DET
aji-31	236	5	effort	effort	NOUN
aji-31	236	6	of	of	ADP
aji-31	236	7	usmanu	usmanu	PROPN
aji-31	236	8	dandodiyo	dandodiyo	PROPN
aji-31	236	9	university	university	PROPN
aji-31	236	10	,	,	PUNCT
aji-31	236	11	glocal	glocal	ADJ
aji-31	236	12	university	university	NOUN
aji-31	236	13	,	,	PUNCT
aji-31	236	14	sharda	sharda	PROPN
aji-31	236	15	university	university	PROPN
aji-31	236	16	,	,	PUNCT
aji-31	236	17	and	and	CCONJ
aji-31	236	18	mewar	mewar	ADJ
aji-31	236	19	university	university	NOUN
aji-31	236	20	for	for	ADP
aji-31	236	21	their	their	PRON
aji-31	236	22	esteemed	esteemed	ADJ
aji-31	236	23	support	support	NOUN
aji-31	236	24	and	and	CCONJ
aji-31	236	25	guidance	guidance	NOUN
aji-31	236	26	towards	towards	ADP
aji-31	236	27	completion	completion	NOUN
aji-31	236	28	of	of	ADP
aji-31	236	29	this	this	DET
aji-31	236	30	review	review	NOUN
aji-31	236	31	article	article	NOUN
aji-31	236	32	.	.	PUNCT
aji-31	237	1	competing	compete	VERB
aji-31	237	2	interests	interest	NOUN
aji-31	237	3	authors	author	NOUN
aji-31	237	4	have	have	AUX
aji-31	237	5	declared	declare	VERB
aji-31	237	6	that	that	SCONJ
aji-31	237	7	no	no	DET
aji-31	237	8	competing	compete	VERB
aji-31	237	9	interests	interest	NOUN
aji-31	237	10	exist	exist	VERB
aji-31	237	11	.	.	PUNCT
aji-31	238	1	references	reference	NOUN
aji-31	238	2	1	1	NUM
aji-31	238	3	.	.	PUNCT
aji-31	238	4	sharma	sharma	PROPN
aji-31	238	5	l.	l.	PROPN
aji-31	238	6	osteoarthritis	osteoarthritis	PROPN
aji-31	238	7	year	year	NOUN
aji-31	238	8	in	in	ADP
aji-31	238	9	review	review	NOUN
aji-31	238	10	2015	2015	NUM
aji-31	238	11	:	:	PUNCT
aji-31	238	12	clinical	clinical	ADJ
aji-31	238	13	.	.	PUNCT
aji-31	239	1	osteoarthritis	osteoarthritis	NOUN
aji-31	239	2	cartilage	cartilage	NOUN
aji-31	239	3	.	.	PUNCT
aji-31	240	1	2016;24(1):36	2016;24(1):36	NUM
aji-31	240	2	-	-	SYM
aji-31	240	3	48	48	NUM
aji-31	240	4	.	.	PUNCT
aji-31	241	1	doi	doi	NOUN
aji-31	241	2	:	:	PUNCT
aji-31	241	3	10.1016	10.1016	NUM
aji-31	241	4	/	/	SYM
aji-31	241	5	j.joca.2015.07.026	j.joca.2015.07.026	PROPN
aji-31	241	6	2	2	NUM
aji-31	241	7	.	.	X
aji-31	241	8	musumeci	musumeci	PROPN
aji-31	241	9	g	g	PROPN
aji-31	241	10	,	,	PUNCT
aji-31	241	11	aiello	aiello	PROPN
aji-31	241	12	fc	fc	PROPN
aji-31	241	13	,	,	PUNCT
aji-31	241	14	szychlinska	szychlinska	PROPN
aji-31	241	15	ma	ma	PROPN
aji-31	241	16	,	,	PUNCT
aji-31	241	17	di	di	PROPN
aji-31	241	18	rosa	rosa	PROPN
aji-31	241	19	m	m	PROPN
aji-31	241	20	,	,	PUNCT
aji-31	241	21	castrogiovanni	castrogiovanni	PROPN
aji-31	241	22	p	p	X
aji-31	241	23	,	,	PUNCT
aji-31	241	24	mobasheri	mobasheri	PROPN
aji-31	241	25	a.	a.	NOUN
aji-31	241	26	osteoarthritis	osteoarthritis	PROPN
aji-31	241	27	in	in	ADP
aji-31	241	28	the	the	DET
aji-31	241	29	xxist	xxist	ADJ
aji-31	241	30	century	century	NOUN
aji-31	241	31	:	:	PUNCT
aji-31	241	32	risk	risk	NOUN
aji-31	241	33	factors	factor	NOUN
aji-31	241	34	and	and	CCONJ
aji-31	241	35	behaviours	behaviour	NOUN
aji-31	241	36	that	that	PRON
aji-31	241	37	influence	influence	NOUN
aji-31	241	38	disease	disease	NOUN
aji-31	241	39	onset	onset	NOUN
aji-31	241	40	and	and	CCONJ
aji-31	241	41	progression	progression	NOUN
aji-31	241	42	.	.	PUNCT
aji-31	242	1	int	int	PROPN
aji-31	242	2	j	j	PROPN
aji-31	242	3	mol	mol	ADP
aji-31	242	4	sci	sci	PROPN
aji-31	242	5	.	.	PUNCT
aji-31	243	1	2015;16(3):6093	2015;16(3):6093	NUM
aji-31	243	2	-	-	SYM
aji-31	243	3	6112	6112	NUM
aji-31	243	4	.	.	PUNCT
aji-31	244	1	doi	doi	NOUN
aji-31	244	2	:	:	PUNCT
aji-31	244	3	10.3390	10.3390	NUM
aji-31	244	4	/	/	SYM
aji-31	244	5	ijms16036093	ijms16036093	PROPN
aji-31	244	6	3	3	NUM
aji-31	244	7	.	.	PUNCT
aji-31	245	1	kim	kim	PROPN
aji-31	245	2	jr	jr	PROPN
aji-31	245	3	,	,	PUNCT
aji-31	245	4	yoo	yoo	PROPN
aji-31	245	5	jj	jj	PROPN
aji-31	245	6	,	,	PUNCT
aji-31	245	7	kim	kim	PROPN
aji-31	245	8	ha	ha	INTJ
aji-31	245	9	.	.	PUNCT
aji-31	245	10	therapeutics	therapeutic	NOUN
aji-31	245	11	in	in	ADP
aji-31	245	12	osteoarthritis	osteoarthritis	NOUN
aji-31	245	13	based	base	VERB
aji-31	245	14	on	on	ADP
aji-31	245	15	an	an	DET
aji-31	245	16	understanding	understanding	NOUN
aji-31	245	17	of	of	ADP
aji-31	245	18	its	its	PRON
aji-31	245	19	molecular	molecular	ADJ
aji-31	245	20	pathogenesis	pathogenesis	NOUN
aji-31	245	21	.	.	PUNCT
aji-31	246	1	int	int	PROPN
aji-31	246	2	j	j	PROPN
aji-31	246	3	mol	mol	ADP
aji-31	246	4	sci	sci	PROPN
aji-31	246	5	.	.	PUNCT
aji-31	246	6	2018;19(3):674	2018;19(3):674	PROPN
aji-31	246	7	.	.	PUNCT
aji-31	247	1	doi	doi	NOUN
aji-31	247	2	:	:	PUNCT
aji-31	247	3	10.3390	10.3390	NUM
aji-31	247	4	/	/	SYM
aji-31	247	5	ijms19030674	ijms19030674	PROPN
aji-31	247	6	4	4	NUM
aji-31	247	7	.	.	PUNCT
aji-31	248	1	hayashi	hayashi	PROPN
aji-31	248	2	d	d	PROPN
aji-31	248	3	,	,	PUNCT
aji-31	248	4	roemer	roemer	PROPN
aji-31	248	5	fw	fw	PROPN
aji-31	248	6	,	,	PUNCT
aji-31	248	7	guermazi	guermazi	PROPN
aji-31	248	8	a.	a.	NOUN
aji-31	248	9	imaging	imaging	NOUN
aji-31	248	10	of	of	ADP
aji-31	248	11	osteoarthritis	osteoarthritis	NOUN
aji-31	248	12	-	-	PUNCT
aji-31	248	13	recent	recent	ADJ
aji-31	248	14	research	research	NOUN
aji-31	248	15	developments	development	NOUN
aji-31	248	16	and	and	CCONJ
aji-31	248	17	future	future	ADJ
aji-31	248	18	perspective	perspective	NOUN
aji-31	248	19	.	.	PUNCT
aji-31	249	1	br	br	PROPN
aji-31	249	2	j	j	PROPN
aji-31	249	3	radiol	radiol	PROPN
aji-31	249	4	.	.	PUNCT
aji-31	250	1	2018;91(1085):20170349	2018;91(1085):20170349	X
aji-31	250	2	.	.	PUNCT
aji-31	250	3	doi	doi	PROPN
aji-31	250	4	:	:	PUNCT
aji-31	250	5	10.1259	10.1259	NUM
aji-31	250	6	/	/	SYM
aji-31	250	7	bjr.20170349	bjr.20170349	NUM
aji-31	250	8	shehu	shehu	NOUN
aji-31	250	9	et	et	PROPN
aji-31	250	10	al	al	PROPN
aji-31	250	11	.	.	PROPN
aji-31	250	12	;	;	PUNCT
aji-31	250	13	aji	aji	PROPN
aji-31	250	14	,	,	PUNCT
aji-31	250	15	3(1	3(1	NUM
aji-31	250	16	):	):	PUNCT
aji-31	250	17	223	223	NUM
aji-31	250	18	-	-	SYM
aji-31	250	19	232	232	NUM
aji-31	250	20	,	,	PUNCT
aji-31	250	21	2020	2020	NUM
aji-31	250	22	;	;	PUNCT
aji-31	250	23	article	article	NOUN
aji-31	250	24	no.aji.57637	no.aji.57637	ADV
aji-31	250	25	230	230	NUM
aji-31	250	26	5	5	NUM
aji-31	250	27	.	.	PUNCT
aji-31	251	1	sun	sun	PROPN
aji-31	251	2	mm	mm	PROPN
aji-31	251	3	,	,	PUNCT
aji-31	251	4	beier	beier	X
aji-31	251	5	f	f	PROPN
aji-31	251	6	,	,	PUNCT
aji-31	251	7	pest	pest	VERB
aji-31	251	8	ma	ma	PROPN
aji-31	251	9	.	.	PUNCT
aji-31	252	1	recent	recent	ADJ
aji-31	252	2	developments	development	NOUN
aji-31	252	3	in	in	ADP
aji-31	252	4	emerging	emerge	VERB
aji-31	252	5	therapeutic	therapeutic	ADJ
aji-31	252	6	targets	target	NOUN
aji-31	252	7	of	of	ADP
aji-31	252	8	osteoarthritis	osteoarthritis	NOUN
aji-31	252	9	.	.	PUNCT
aji-31	253	1	curr	curr	PROPN
aji-31	253	2	opin	opin	PROPN
aji-31	253	3	rheumatol	rheumatol	NOUN
aji-31	253	4	.	.	PUNCT
aji-31	254	1	2017;29(1):96	2017;29(1):96	NUM
aji-31	254	2	-	-	SYM
aji-31	254	3	102	102	NUM
aji-31	254	4	.	.	PUNCT
aji-31	255	1	doi	doi	NOUN
aji-31	255	2	:	:	PUNCT
aji-31	255	3	10.1097	10.1097	NUM
aji-31	255	4	/	/	SYM
aji-31	255	5	bor.0000000000000351	bor.0000000000000351	NUM
aji-31	255	6	6	6	NUM
aji-31	255	7	.	.	PUNCT
aji-31	256	1	guilak	guilak	ADJ
aji-31	256	2	f	f	PROPN
aji-31	256	3	,	,	PUNCT
aji-31	256	4	nims	nims	PROPN
aji-31	256	5	rj	rj	PROPN
aji-31	256	6	,	,	PUNCT
aji-31	256	7	dicks	dick	VERB
aji-31	256	8	a	a	DET
aji-31	256	9	,	,	PUNCT
aji-31	256	10	wu	wu	PROPN
aji-31	256	11	cl	cl	PROPN
aji-31	256	12	,	,	PUNCT
aji-31	256	13	meulenbelt	meulenbelt	VERB
aji-31	256	14	i.	i.	NOUN
aji-31	256	15	osteoarthritis	osteoarthritis	PROPN
aji-31	256	16	as	as	ADP
aji-31	256	17	a	a	DET
aji-31	256	18	disease	disease	NOUN
aji-31	256	19	of	of	ADP
aji-31	256	20	the	the	DET
aji-31	256	21	cartilage	cartilage	NOUN
aji-31	256	22	pericellular	pericellular	ADJ
aji-31	256	23	matrix	matrix	NOUN
aji-31	256	24	.	.	PUNCT
aji-31	257	1	matrix	matrix	NOUN
aji-31	257	2	biology	biology	NOUN
aji-31	257	3	:	:	PUNCT
aji-31	257	4	journal	journal	NOUN
aji-31	257	5	of	of	ADP
aji-31	257	6	the	the	DET
aji-31	257	7	international	international	ADJ
aji-31	257	8	society	society	NOUN
aji-31	257	9	for	for	ADP
aji-31	257	10	matrix	matrix	NOUN
aji-31	257	11	biology	biology	NOUN
aji-31	257	12	.	.	PUNCT
aji-31	258	1	2018;71	2018;71	NUM
aji-31	258	2	-	-	PUNCT
aji-31	258	3	72,40	72,40	ADJ
aji-31	258	4	–	–	PUNCT
aji-31	258	5	50	50	NUM
aji-31	258	6	.	.	PUNCT
aji-31	259	1	doi	doi	NOUN
aji-31	259	2	:	:	PUNCT
aji-31	259	3	10.1016	10.1016	NUM
aji-31	259	4	/	/	SYM
aji-31	259	5	j.matbio.2018.05.008	j.matbio.2018.05.008	PROPN
aji-31	259	6	7	7	NUM
aji-31	259	7	.	.	PUNCT
aji-31	259	8	pal	pal	PROPN
aji-31	259	9	cp	cp	PROPN
aji-31	259	10	,	,	PUNCT
aji-31	259	11	singh	singh	PROPN
aji-31	259	12	p	p	PROPN
aji-31	259	13	,	,	PUNCT
aji-31	259	14	chaturvedi	chaturvedi	PROPN
aji-31	259	15	s	s	PROPN
aji-31	259	16	,	,	PUNCT
aji-31	259	17	pruthi	pruthi	PROPN
aji-31	259	18	kk	kk	PROPN
aji-31	259	19	,	,	PUNCT
aji-31	259	20	vij	vij	PROPN
aji-31	259	21	a.	a.	NOUN
aji-31	259	22	epidemiology	epidemiology	NOUN
aji-31	259	23	of	of	ADP
aji-31	259	24	knee	knee	NOUN
aji-31	259	25	osteoarthritis	osteoarthritis	PROPN
aji-31	259	26	in	in	ADP
aji-31	259	27	india	india	PROPN
aji-31	259	28	and	and	CCONJ
aji-31	259	29	related	related	ADJ
aji-31	259	30	factors	factor	NOUN
aji-31	259	31	.	.	PUNCT
aji-31	260	1	indian	indian	ADJ
aji-31	260	2	j	j	PROPN
aji-31	260	3	orthop	orthop	NOUN
aji-31	260	4	.	.	PUNCT
aji-31	261	1	2016;50(5):518	2016;50(5):518	NUM
aji-31	261	2	-	-	PUNCT
aji-31	261	3	522	522	NUM
aji-31	261	4	.	.	PUNCT
aji-31	262	1	doi	doi	NOUN
aji-31	262	2	:	:	PUNCT
aji-31	262	3	10.4103/0019	10.4103/0019	NUM
aji-31	262	4	-	-	NUM
aji-31	262	5	5413.189608	5413.189608	NUM
aji-31	262	6	8	8	NUM
aji-31	262	7	.	.	PUNCT
aji-31	263	1	wallace	wallace	PROPN
aji-31	263	2	ij	ij	PROPN
aji-31	263	3	,	,	PUNCT
aji-31	263	4	worthington	worthington	PROPN
aji-31	263	5	s	s	PROPN
aji-31	263	6	,	,	PUNCT
aji-31	263	7	felson	felson	NOUN
aji-31	263	8	dt	dt	PROPN
aji-31	263	9	,	,	PUNCT
aji-31	263	10	et	et	PROPN
aji-31	263	11	al	al	PROPN
aji-31	263	12	.	.	PUNCT
aji-31	264	1	knee	knee	PROPN
aji-31	264	2	osteoarthritis	osteoarthritis	NOUN
aji-31	264	3	has	have	AUX
aji-31	264	4	doubled	double	VERB
aji-31	264	5	in	in	ADP
aji-31	264	6	prevalence	prevalence	NOUN
aji-31	264	7	since	since	SCONJ
aji-31	264	8	the	the	DET
aji-31	264	9	mid-20	mid-20	PROPN
aji-31	264	10	th	th	VERB
aji-31	264	11	century	century	NOUN
aji-31	264	12	.	.	PUNCT
aji-31	265	1	proc	proc	PROPN
aji-31	265	2	natl	natl	PROPN
aji-31	265	3	acad	acad	PROPN
aji-31	265	4	sci	sci	PROPN
aji-31	265	5	usa	usa	PROPN
aji-31	265	6	.	.	PUNCT
aji-31	266	1	2017;114(35	2017;114(35	PROPN
aji-31	266	2	):	):	PUNCT
aji-31	266	3	9332	9332	NUM
aji-31	266	4	-	-	SYM
aji-31	266	5	9336	9336	NUM
aji-31	266	6	.	.	PUNCT
aji-31	267	1	doi	doi	NOUN
aji-31	267	2	:	:	PUNCT
aji-31	267	3	10.1073	10.1073	NUM
aji-31	267	4	/	/	SYM
aji-31	267	5	pnas.1703856114	pnas.1703856114	PROPN
aji-31	267	6	9	9	NUM
aji-31	267	7	.	.	PUNCT
aji-31	267	8	plotnikoff	plotnikoff	NOUN
aji-31	267	9	r	r	PROPN
aji-31	267	10	,	,	PUNCT
aji-31	267	11	karunamuni	karunamuni	PROPN
aji-31	267	12	n	n	CCONJ
aji-31	267	13	,	,	PUNCT
aji-31	267	14	lytvyak	lytvyak	NOUN
aji-31	267	15	e	e	NOUN
aji-31	267	16	,	,	PUNCT
aji-31	267	17	et	et	PROPN
aji-31	267	18	al	al	PROPN
aji-31	267	19	.	.	PUNCT
aji-31	268	1	osteoarthritis	osteoarthritis	NOUN
aji-31	268	2	prevalence	prevalence	NOUN
aji-31	268	3	and	and	CCONJ
aji-31	268	4	modifiable	modifiable	ADJ
aji-31	268	5	factors	factor	NOUN
aji-31	268	6	:	:	PUNCT
aji-31	268	7	a	a	DET
aji-31	268	8	population	population	NOUN
aji-31	268	9	study	study	NOUN
aji-31	268	10	.	.	PUNCT
aji-31	269	1	bmc	bmc	ADJ
aji-31	269	2	public	public	ADJ
aji-31	269	3	health	health	NOUN
aji-31	269	4	.	.	PUNCT
aji-31	270	1	2015;15(1):1195	2015;15(1):1195	NUM
aji-31	270	2	.	.	PUNCT
aji-31	271	1	doi	doi	NOUN
aji-31	271	2	:	:	PUNCT
aji-31	271	3	10.1186	10.1186	NUM
aji-31	271	4	/	/	SYM
aji-31	271	5	s12889	s12889	NOUN
aji-31	271	6	-	-	PUNCT
aji-31	271	7	015	015	NUM
aji-31	271	8	-	-	PUNCT
aji-31	271	9	2529	2529	NUM
aji-31	271	10	-	-	SYM
aji-31	271	11	0	0	NUM
aji-31	271	12	10	10	NUM
aji-31	271	13	.	.	PUNCT
aji-31	272	1	venkatachalam	venkatachalam	PROPN
aji-31	272	2	j	j	PROPN
aji-31	272	3	,	,	PUNCT
aji-31	272	4	natesan	natesan	PROPN
aji-31	272	5	m	m	PROPN
aji-31	272	6	,	,	PUNCT
aji-31	272	7	eswaran	eswaran	PROPN
aji-31	272	8	m	m	PROPN
aji-31	272	9	,	,	PUNCT
aji-31	272	10	johnson	johnson	PROPN
aji-31	272	11	aks	aks	PROPN
aji-31	272	12	,	,	PUNCT
aji-31	272	13	bharath	bharath	PROPN
aji-31	272	14	v	v	PROPN
aji-31	272	15	,	,	PUNCT
aji-31	272	16	singh	singh	PROPN
aji-31	272	17	z.	z.	PROPN
aji-31	272	18	prevalence	prevalence	NOUN
aji-31	272	19	of	of	ADP
aji-31	272	20	osteoarthritis	osteoarthritis	NOUN
aji-31	272	21	of	of	ADP
aji-31	272	22	knee	knee	NOUN
aji-31	272	23	joint	joint	NOUN
aji-31	272	24	among	among	ADP
aji-31	272	25	adult	adult	NOUN
aji-31	272	26	population	population	NOUN
aji-31	272	27	in	in	ADP
aji-31	272	28	a	a	DET
aji-31	272	29	rural	rural	ADJ
aji-31	272	30	area	area	NOUN
aji-31	272	31	of	of	ADP
aji-31	272	32	kanchipuram	kanchipuram	PROPN
aji-31	272	33	district	district	PROPN
aji-31	272	34	,	,	PUNCT
aji-31	272	35	tamil	tamil	PROPN
aji-31	272	36	nadu	nadu	PROPN
aji-31	272	37	.	.	PUNCT
aji-31	273	1	indian	indian	PROPN
aji-31	273	2	j	j	PROPN
aji-31	273	3	public	public	ADJ
aji-31	273	4	health	health	NOUN
aji-31	273	5	.	.	PUNCT
aji-31	274	1	2018;62(2):117	2018;62(2):117	NUM
aji-31	274	2	-	-	SYM
aji-31	274	3	122	122	NUM
aji-31	274	4	.	.	PUNCT
aji-31	275	1	11	11	NUM
aji-31	275	2	.	.	PUNCT
aji-31	276	1	prevalence	prevalence	NOUN
aji-31	276	2	of	of	ADP
aji-31	276	3	arthritis	arthritis	NOUN
aji-31	276	4	and	and	CCONJ
aji-31	276	5	rheumatic	rheumatic	ADJ
aji-31	276	6	diseases	disease	NOUN
aji-31	276	7	around	around	ADP
aji-31	276	8	the	the	DET
aji-31	276	9	world	world	NOUN
aji-31	276	10	.	.	PUNCT
aji-31	277	1	a	a	DET
aji-31	277	2	growing	grow	VERB
aji-31	277	3	burden	burden	NOUN
aji-31	277	4	and	and	CCONJ
aji-31	277	5	implications	implication	NOUN
aji-31	277	6	for	for	ADP
aji-31	277	7	health	health	NOUN
aji-31	277	8	care	care	NOUN
aji-31	277	9	needs	need	NOUN
aji-31	277	10	.	.	PUNCT
aji-31	278	1	available	available	ADJ
aji-31	278	2	:	:	PUNCT
aji-31	278	3	http://www.modelsofcare.ca	http://www.modelsofcare.ca	NOUN
aji-31	278	4	/	/	SYM
aji-31	278	5	pdf/1	pdf/1	PROPN
aji-31	278	6	0-02.pdf	0-02.pdf	NUM
aji-31	278	7	12	12	NUM
aji-31	278	8	.	.	PUNCT
aji-31	278	9	tang	tang	PROPN
aji-31	279	1	x	x	PROPN
aji-31	279	2	,	,	PUNCT
aji-31	279	3	wang	wang	PROPN
aji-31	279	4	s	s	PROPN
aji-31	279	5	,	,	PUNCT
aji-31	279	6	zhan	zhan	PROPN
aji-31	279	7	s	s	PROPN
aji-31	279	8	,	,	PUNCT
aji-31	279	9	et	et	PROPN
aji-31	279	10	al	al	PROPN
aji-31	279	11	.	.	PUNCT
aji-31	280	1	the	the	DET
aji-31	280	2	prevalence	prevalence	NOUN
aji-31	280	3	of	of	ADP
aji-31	280	4	symptomatic	symptomatic	ADJ
aji-31	280	5	knee	knee	NOUN
aji-31	280	6	osteoarthritis	osteoarthritis	NOUN
aji-31	280	7	in	in	ADP
aji-31	280	8	china	china	PROPN
aji-31	280	9	:	:	PUNCT
aji-31	280	10	results	result	NOUN
aji-31	280	11	from	from	ADP
aji-31	280	12	the	the	DET
aji-31	280	13	china	china	PROPN
aji-31	280	14	health	health	PROPN
aji-31	280	15	and	and	CCONJ
aji-31	280	16	retirement	retirement	PROPN
aji-31	280	17	longitudinal	longitudinal	ADJ
aji-31	280	18	study	study	NOUN
aji-31	280	19	.	.	PUNCT
aji-31	281	1	arthritis	arthritis	NOUN
aji-31	281	2	rheumatol	rheumatol	NOUN
aji-31	281	3	.	.	PUNCT
aji-31	282	1	2016;68(3	2016;68(3	NUM
aji-31	282	2	):	):	PUNCT
aji-31	282	3	648	648	NUM
aji-31	282	4	-	-	SYM
aji-31	282	5	653	653	NUM
aji-31	282	6	.	.	PUNCT
aji-31	282	7	doi	doi	NOUN
aji-31	282	8	:	:	PUNCT
aji-31	282	9	10.1002	10.1002	NUM
aji-31	282	10	/	/	SYM
aji-31	282	11	art.39465	art.39465	SYM
aji-31	282	12	13	13	NUM
aji-31	282	13	.	.	PUNCT
aji-31	282	14	loeser	loeser	PROPN
aji-31	282	15	rf	rf	PROPN
aji-31	282	16	.	.	PUNCT
aji-31	282	17	age	age	NOUN
aji-31	282	18	-	-	PUNCT
aji-31	282	19	related	relate	VERB
aji-31	282	20	changes	change	NOUN
aji-31	282	21	in	in	ADP
aji-31	282	22	the	the	DET
aji-31	282	23	musculoskeletal	musculoskeletal	ADJ
aji-31	282	24	system	system	NOUN
aji-31	282	25	and	and	CCONJ
aji-31	282	26	the	the	DET
aji-31	282	27	development	development	NOUN
aji-31	282	28	of	of	ADP
aji-31	282	29	osteoarthritis	osteoarthritis	NOUN
aji-31	282	30	.	.	PUNCT
aji-31	283	1	clin	clin	PROPN
aji-31	283	2	geriatr	geriatr	PROPN
aji-31	283	3	med	med	PROPN
aji-31	283	4	.	.	PUNCT
aji-31	284	1	2010;26(3):371	2010;26(3):371	NUM
aji-31	284	2	-	-	SYM
aji-31	284	3	386	386	NUM
aji-31	284	4	.	.	PUNCT
aji-31	285	1	doi	doi	NOUN
aji-31	285	2	:	:	PUNCT
aji-31	285	3	10.1016	10.1016	NUM
aji-31	285	4	/	/	SYM
aji-31	285	5	j.cger.2010.03.002	j.cger.2010.03.002	NOUN
aji-31	285	6	14	14	NUM
aji-31	285	7	.	.	PUNCT
aji-31	286	1	onuora	onuora	PROPN
aji-31	286	2	s.	s.	PROPN
aji-31	286	3	osteoarthritis	osteoarthritis	PROPN
aji-31	286	4	:	:	PUNCT
aji-31	286	5	cartilage	cartilage	NOUN
aji-31	286	6	matrix	matrix	NOUN
aji-31	286	7	stiffness	stiffness	NOUN
aji-31	286	8	regulates	regulate	VERB
aji-31	286	9	chondrocyte	chondrocyte	NOUN
aji-31	286	10	metabolism	metabolism	NOUN
aji-31	286	11	and	and	CCONJ
aji-31	286	12	oa	oa	ADP
aji-31	286	13	pathogenesis	pathogenesis	NOUN
aji-31	286	14	.	.	PUNCT
aji-31	287	1	nat	nat	PROPN
aji-31	287	2	rev	rev	PROPN
aji-31	287	3	rheumatol	rheumatol	NOUN
aji-31	287	4	.	.	PUNCT
aji-31	288	1	2015;11(9):504	2015;11(9):504	NUM
aji-31	288	2	.	.	PUNCT
aji-31	289	1	15	15	NUM
aji-31	289	2	.	.	PUNCT
aji-31	290	1	minas	minas	PROPN
aji-31	290	2	t	t	PROPN
aji-31	290	3	,	,	PUNCT
aji-31	290	4	gomoll	gomoll	NOUN
aji-31	290	5	ah	ah	INTJ
aji-31	290	6	,	,	PUNCT
aji-31	290	7	solhpour	solhpour	PROPN
aji-31	290	8	s	s	PROPN
aji-31	290	9	,	,	PUNCT
aji-31	290	10	rosenberger	rosenberger	PROPN
aji-31	290	11	r	r	PROPN
aji-31	290	12	,	,	PUNCT
aji-31	290	13	probst	probst	NOUN
aji-31	290	14	c	c	NOUN
aji-31	290	15	,	,	PUNCT
aji-31	290	16	bryant	bryant	PROPN
aji-31	290	17	t.	t.	PROPN
aji-31	290	18	autologous	autologous	ADJ
aji-31	290	19	chondrocyte	chondrocyte	PROPN
aji-31	290	20	implantation	implantation	NOUN
aji-31	290	21	for	for	ADP
aji-31	290	22	joint	joint	ADJ
aji-31	290	23	preservation	preservation	NOUN
aji-31	290	24	in	in	ADP
aji-31	290	25	patients	patient	NOUN
aji-31	290	26	with	with	ADP
aji-31	290	27	early	early	ADJ
aji-31	290	28	osteoarthritis	osteoarthritis	NOUN
aji-31	290	29	.	.	PUNCT
aji-31	291	1	clin	clin	PROPN
aji-31	291	2	orthop	orthop	PROPN
aji-31	291	3	relat	relat	PROPN
aji-31	291	4	res	re	NOUN
aji-31	291	5	.	.	PUNCT
aji-31	292	1	2010;468(1):147	2010;468(1):147	NUM
aji-31	292	2	-	-	SYM
aji-31	292	3	157	157	NUM
aji-31	292	4	.	.	PUNCT
aji-31	293	1	doi	doi	NOUN
aji-31	293	2	:	:	PUNCT
aji-31	293	3	10.1007	10.1007	NUM
aji-31	293	4	/	/	SYM
aji-31	293	5	s11999	s11999	NOUN
aji-31	293	6	-	-	PUNCT
aji-31	293	7	009	009	NUM
aji-31	293	8	-	-	PUNCT
aji-31	293	9	0998	0998	NUM
aji-31	293	10	-	-	SYM
aji-31	293	11	0	0	NUM
aji-31	293	12	16	16	NUM
aji-31	293	13	.	.	PUNCT
aji-31	294	1	osteoarthritic	osteoarthritic	ADJ
aji-31	294	2	joint	joint	ADJ
aji-31	294	3	and	and	CCONJ
aji-31	294	4	healthy	healthy	ADJ
aji-31	294	5	joint	joint	NOUN
aji-31	294	6	.	.	PUNCT
aji-31	295	1	available	available	ADJ
aji-31	295	2	:	:	PUNCT
aji-31	295	3	https://www.shutterstock.com	https://www.shutterstock.com	X
aji-31	295	4	/	/	SYM
aji-31	295	5	im	im	CCONJ
aji-31	295	6	age	age	NOUN
aji-31	295	7	-	-	PUNCT
aji-31	295	8	vector	vector	NOUN
aji-31	295	9	/	/	SYM
aji-31	295	10	osteoarthritis	osteoarthritis	NOUN
aji-31	295	11	-	-	PUNCT
aji-31	295	12	arthritis	arthritis	NOUN
aji-31	295	13	-	-	PUNCT
aji-31	295	14	painwithin	painwithin	ADJ
aji-31	295	15	-	-	PUNCT
aji-31	295	16	joint	joint	NOUN
aji-31	295	17	-	-	PUNCT
aji-31	295	18	degenerative-219992428	degenerative-219992428	ADJ
aji-31	295	19	17	17	NUM
aji-31	295	20	.	.	PUNCT
aji-31	296	1	development	development	NOUN
aji-31	296	2	of	of	ADP
aji-31	296	3	osteoarthritis	osteoarthritis	NOUN
aji-31	296	4	.	.	PUNCT
aji-31	297	1	available	available	ADJ
aji-31	297	2	:	:	PUNCT
aji-31	297	3	https://teachmesurgery.com	https://teachmesurgery.com	PROPN
aji-31	297	4	/	/	SYM
aji-31	297	5	orth	orth	PROPN
aji-31	297	6	opaedic	opaedic	PROPN
aji-31	297	7	/	/	SYM
aji-31	297	8	principles	principle	NOUN
aji-31	297	9	/	/	SYM
aji-31	297	10	osteoarthritis/	osteoarthritis/	NUM
aji-31	297	11	18	18	NUM
aji-31	297	12	.	.	PUNCT
aji-31	297	13	heijink	heijink	VERB
aji-31	297	14	a	a	PRON
aji-31	297	15	,	,	PUNCT
aji-31	297	16	gomoll	gomoll	NOUN
aji-31	297	17	ah	ah	INTJ
aji-31	297	18	,	,	PUNCT
aji-31	297	19	madry	madry	ADJ
aji-31	297	20	h	h	NOUN
aji-31	297	21	,	,	PUNCT
aji-31	297	22	drobnič	drobnič	PROPN
aji-31	297	23	m	m	PROPN
aji-31	297	24	,	,	PUNCT
aji-31	297	25	filardo	filardo	VERB
aji-31	297	26	g	g	NOUN
aji-31	297	27	,	,	PUNCT
aji-31	297	28	espregueira	espregueira	NOUN
aji-31	297	29	-	-	PUNCT
aji-31	297	30	mendes	mende	NOUN
aji-31	297	31	j	j	PROPN
aji-31	297	32	,	,	PUNCT
aji-31	297	33	van	van	PROPN
aji-31	297	34	dijk	dijk	PROPN
aji-31	297	35	cn	cn	PROPN
aji-31	297	36	.	.	PROPN
aji-31	297	37	biomechanical	biomechanical	ADJ
aji-31	297	38	considerations	consideration	NOUN
aji-31	297	39	in	in	ADP
aji-31	297	40	the	the	DET
aji-31	297	41	pathogenesis	pathogenesis	NOUN
aji-31	297	42	of	of	ADP
aji-31	297	43	osteoarthritis	osteoarthritis	NOUN
aji-31	297	44	of	of	ADP
aji-31	297	45	the	the	DET
aji-31	297	46	knee	knee	NOUN
aji-31	297	47	.	.	PUNCT
aji-31	298	1	knee	knee	NOUN
aji-31	298	2	surgery	surgery	NOUN
aji-31	298	3	,	,	PUNCT
aji-31	298	4	sports	sport	NOUN
aji-31	298	5	traumatology	traumatology	NOUN
aji-31	298	6	,	,	PUNCT
aji-31	298	7	arthroscopy	arthroscopy	NOUN
aji-31	298	8	:	:	PUNCT
aji-31	298	9	official	official	ADJ
aji-31	298	10	journal	journal	NOUN
aji-31	298	11	of	of	ADP
aji-31	298	12	the	the	DET
aji-31	298	13	esska	esska	NOUN
aji-31	298	14	.	.	PUNCT
aji-31	299	1	2012;20(3):423–435	2012;20(3):423–435	X
aji-31	299	2	.	.	PUNCT
aji-31	299	3	doi	doi	NOUN
aji-31	299	4	:	:	PUNCT
aji-31	299	5	10.1007	10.1007	NUM
aji-31	299	6	/	/	SYM
aji-31	299	7	s00167	s00167	NOUN
aji-31	299	8	-	-	PUNCT
aji-31	299	9	011	011	NUM
aji-31	299	10	-	-	PUNCT
aji-31	299	11	1818	1818	NUM
aji-31	299	12	-	-	SYM
aji-31	299	13	0	0	NUM
aji-31	299	14	19	19	NUM
aji-31	299	15	.	.	PUNCT
aji-31	300	1	michael	michael	PROPN
aji-31	300	2	jw	jw	PROPN
aji-31	300	3	,	,	PUNCT
aji-31	300	4	schlüter	schlüter	PROPN
aji-31	300	5	-	-	PUNCT
aji-31	300	6	brust	brust	PROPN
aji-31	300	7	ku	ku	PROPN
aji-31	300	8	,	,	PUNCT
aji-31	300	9	eysel	eysel	NOUN
aji-31	300	10	p.	p.	NOUN
aji-31	300	11	the	the	DET
aji-31	300	12	epidemiology	epidemiology	NOUN
aji-31	300	13	,	,	PUNCT
aji-31	300	14	etiology	etiology	NOUN
aji-31	300	15	,	,	PUNCT
aji-31	300	16	diagnosis	diagnosis	NOUN
aji-31	300	17	and	and	CCONJ
aji-31	300	18	treatment	treatment	NOUN
aji-31	300	19	of	of	ADP
aji-31	300	20	osteoarthritis	osteoarthritis	NOUN
aji-31	300	21	of	of	ADP
aji-31	300	22	the	the	DET
aji-31	300	23	knee	knee	NOUN
aji-31	300	24	.	.	PUNCT
aji-31	301	1	dtsch	dtsch	PROPN
aji-31	301	2	arztebl	arztebl	PROPN
aji-31	301	3	int	int	PROPN
aji-31	301	4	.	.	PUNCT
aji-31	302	1	2010;107(9):152	2010;107(9):152	NUM
aji-31	302	2	-	-	SYM
aji-31	302	3	162	162	NUM
aji-31	302	4	.	.	PUNCT
aji-31	303	1	doi	doi	NOUN
aji-31	303	2	:	:	PUNCT
aji-31	303	3	10.3238	10.3238	NUM
aji-31	303	4	/	/	SYM
aji-31	303	5	arztebl.2010.0152	arztebl.2010.0152	PROPN
aji-31	303	6	20	20	NUM
aji-31	303	7	.	.	PUNCT
aji-31	304	1	kuyinu	kuyinu	PROPN
aji-31	304	2	el	el	PROPN
aji-31	304	3	,	,	PUNCT
aji-31	304	4	narayanan	narayanan	PROPN
aji-31	304	5	g	g	PROPN
aji-31	304	6	,	,	PUNCT
aji-31	304	7	nair	nair	PROPN
aji-31	304	8	ls	ls	PROPN
aji-31	304	9	,	,	PUNCT
aji-31	304	10	laurencin	laurencin	PROPN
aji-31	304	11	ct	ct	PROPN
aji-31	304	12	.	.	PUNCT
aji-31	305	1	animal	animal	NOUN
aji-31	305	2	models	model	NOUN
aji-31	305	3	of	of	ADP
aji-31	305	4	osteoarthritis	osteoarthritis	NOUN
aji-31	305	5	:	:	PUNCT
aji-31	305	6	classification	classification	NOUN
aji-31	305	7	,	,	PUNCT
aji-31	305	8	update	update	NOUN
aji-31	305	9	and	and	CCONJ
aji-31	305	10	measurement	measurement	NOUN
aji-31	305	11	of	of	ADP
aji-31	305	12	outcomes	outcome	NOUN
aji-31	305	13	.	.	PUNCT
aji-31	306	1	j	j	PROPN
aji-31	306	2	orthop	orthop	PROPN
aji-31	306	3	surg	surg	NOUN
aji-31	306	4	res	re	NOUN
aji-31	306	5	.	.	PUNCT
aji-31	307	1	2016;11(1):19	2016;11(1):19	NUM
aji-31	307	2	.	.	PUNCT
aji-31	307	3	doi	doi	PROPN
aji-31	307	4	:	:	PUNCT
aji-31	307	5	10.1186	10.1186	NUM
aji-31	307	6	/	/	SYM
aji-31	307	7	s13018	s13018	PROPN
aji-31	307	8	-	-	PUNCT
aji-31	307	9	016	016	NUM
aji-31	307	10	-	-	PUNCT
aji-31	307	11	0346	0346	NUM
aji-31	307	12	-	-	SYM
aji-31	307	13	5	5	NUM
aji-31	307	14	21	21	NUM
aji-31	307	15	.	.	PUNCT
aji-31	308	1	verdonk	verdonk	PROPN
aji-31	308	2	pcm	pcm	PROPN
aji-31	308	3	,	,	PUNCT
aji-31	308	4	forsyth	forsyth	PROPN
aji-31	308	5	rg	rg	PROPN
aji-31	308	6	,	,	PUNCT
aji-31	308	7	wang	wang	PROPN
aji-31	308	8	j	j	PROPN
aji-31	308	9	,	,	PUNCT
aji-31	308	10	et	et	PROPN
aji-31	308	11	al	al	PROPN
aji-31	308	12	.	.	PROPN
aji-31	309	1	characterisation	characterisation	NOUN
aji-31	309	2	of	of	ADP
aji-31	309	3	human	human	ADJ
aji-31	309	4	knee	knee	PROPN
aji-31	309	5	meniscus	meniscus	NOUN
aji-31	309	6	cell	cell	NOUN
aji-31	309	7	phenotype	phenotype	NOUN
aji-31	309	8	.	.	PUNCT
aji-31	310	1	osteoarthritis	osteoarthritis	NOUN
aji-31	310	2	cartilage	cartilage	NOUN
aji-31	310	3	.	.	PUNCT
aji-31	311	1	2005;13(7):548	2005;13(7):548	NUM
aji-31	311	2	-	-	SYM
aji-31	311	3	560	560	NUM
aji-31	311	4	.	.	PUNCT
aji-31	312	1	doi	doi	NOUN
aji-31	312	2	:	:	PUNCT
aji-31	312	3	10.1016	10.1016	NUM
aji-31	312	4	/	/	SYM
aji-31	312	5	j.joca.2005.01.010	j.joca.2005.01.010	NOUN
aji-31	312	6	22	22	NUM
aji-31	312	7	.	.	PUNCT
aji-31	313	1	buckwalter	buckwalter	PROPN
aji-31	313	2	ja	ja	PROPN
aji-31	313	3	,	,	PUNCT
aji-31	313	4	mankin	mankin	PROPN
aji-31	313	5	hj	hj	PROPN
aji-31	313	6	,	,	PUNCT
aji-31	313	7	grodzinsky	grodzinsky	PROPN
aji-31	313	8	aj	aj	PROPN
aji-31	313	9	.	.	PUNCT
aji-31	313	10	articular	articular	ADJ
aji-31	313	11	cartilage	cartilage	NOUN
aji-31	313	12	and	and	CCONJ
aji-31	313	13	osteoarthritis	osteoarthritis	NOUN
aji-31	313	14	.	.	PUNCT
aji-31	314	1	instr	instr	PROPN
aji-31	314	2	course	course	PROPN
aji-31	314	3	lect	lect	NOUN
aji-31	314	4	.	.	PUNCT
aji-31	315	1	2005;54:465	2005;54:465	NUM
aji-31	315	2	-	-	SYM
aji-31	315	3	480	480	NUM
aji-31	315	4	.	.	PUNCT
aji-31	316	1	23	23	NUM
aji-31	316	2	.	.	PUNCT
aji-31	317	1	smith	smith	PROPN
aji-31	317	2	md	md	PROPN
aji-31	317	3	.	.	PUNCT
aji-31	318	1	the	the	DET
aji-31	318	2	normal	normal	ADJ
aji-31	318	3	synovium	synovium	NOUN
aji-31	318	4	.	.	PUNCT
aji-31	319	1	open	open	ADJ
aji-31	319	2	rheumatol	rheumatol	PROPN
aji-31	319	3	j.	j.	PROPN
aji-31	319	4	2011;5:100	2011;5:100	PROPN
aji-31	319	5	-	-	SYM
aji-31	319	6	106	106	NUM
aji-31	319	7	.	.	PUNCT
aji-31	320	1	doi	doi	NOUN
aji-31	320	2	:	:	PUNCT
aji-31	320	3	10.2174/1874312901105010100	10.2174/1874312901105010100	NUM
aji-31	320	4	24	24	NUM
aji-31	320	5	.	.	PUNCT
aji-31	320	6	de	de	PROPN
aji-31	320	7	sousa	sousa	PROPN
aji-31	320	8	eb	eb	PROPN
aji-31	320	9	,	,	PUNCT
aji-31	320	10	casado	casado	PROPN
aji-31	320	11	pl	pl	PROPN
aji-31	320	12	,	,	PUNCT
aji-31	320	13	moura	moura	PROPN
aji-31	320	14	neto	neto	PROPN
aji-31	320	15	v	v	PROPN
aji-31	320	16	,	,	PUNCT
aji-31	320	17	duarte	duarte	PROPN
aji-31	320	18	me	me	PROPN
aji-31	320	19	,	,	PUNCT
aji-31	320	20	aguiar	aguiar	NOUN
aji-31	320	21	dp	dp	PROPN
aji-31	320	22	.	.	PROPN
aji-31	320	23	synovial	synovial	ADJ
aji-31	320	24	fluid	fluid	NOUN
aji-31	320	25	and	and	CCONJ
aji-31	320	26	synovial	synovial	ADJ
aji-31	320	27	membrane	membrane	NOUN
aji-31	320	28	mesenchymal	mesenchymal	NOUN
aji-31	320	29	stem	stem	NOUN
aji-31	320	30	cells	cell	NOUN
aji-31	320	31	:	:	PUNCT
aji-31	320	32	latest	late	ADJ
aji-31	320	33	discoveries	discovery	NOUN
aji-31	320	34	and	and	CCONJ
aji-31	320	35	therapeutic	therapeutic	ADJ
aji-31	320	36	perspectives	perspective	NOUN
aji-31	320	37	.	.	PUNCT
aji-31	321	1	stem	stem	NOUN
aji-31	321	2	cell	cell	NOUN
aji-31	321	3	res	re	NOUN
aji-31	321	4	ther	ther	ADV
aji-31	321	5	.	.	PUNCT
aji-31	322	1	2014;5(5):112	2014;5(5):112	X
aji-31	322	2	.	.	PUNCT
aji-31	322	3	doi	doi	NOUN
aji-31	322	4	:	:	PUNCT
aji-31	322	5	10.1186	10.1186	NUM
aji-31	322	6	/	/	SYM
aji-31	322	7	scrt501	scrt501	PROPN
aji-31	322	8	25	25	NUM
aji-31	322	9	.	.	PUNCT
aji-31	323	1	orlowsky	orlowsky	PROPN
aji-31	323	2	ew	ew	PROPN
aji-31	323	3	,	,	PUNCT
aji-31	323	4	kraus	kraus	PROPN
aji-31	323	5	vb	vb	PROPN
aji-31	323	6	.	.	PUNCT
aji-31	324	1	the	the	DET
aji-31	324	2	role	role	NOUN
aji-31	324	3	of	of	ADP
aji-31	324	4	innate	innate	ADJ
aji-31	324	5	immunity	immunity	NOUN
aji-31	324	6	in	in	ADP
aji-31	324	7	osteoarthritis	osteoarthritis	NOUN
aji-31	324	8	:	:	PUNCT
aji-31	324	9	when	when	SCONJ
aji-31	324	10	our	our	PRON
aji-31	324	11	first	first	ADJ
aji-31	324	12	line	line	NOUN
aji-31	324	13	of	of	ADP
aji-31	324	14	defense	defense	NOUN
aji-31	324	15	goes	go	VERB
aji-31	324	16	on	on	ADP
aji-31	324	17	the	the	DET
aji-31	324	18	offensive	offensive	NOUN
aji-31	324	19	.	.	PUNCT
aji-31	325	1	j	j	PROPN
aji-31	325	2	rheumatol	rheumatol	NOUN
aji-31	325	3	.	.	PUNCT
aji-31	326	1	2015;42(3):363	2015;42(3):363	NOUN
aji-31	326	2	-	-	SYM
aji-31	326	3	371	371	NUM
aji-31	326	4	.	.	PUNCT
aji-31	327	1	doi	doi	NOUN
aji-31	327	2	:	:	PUNCT
aji-31	327	3	10.3899	10.3899	NUM
aji-31	327	4	/	/	SYM
aji-31	327	5	jrheum.140382	jrheum.140382	PROPN
aji-31	327	6	http://www.modelsofcare.ca/pdf/10-02.pdf	http://www.modelsofcare.ca/pdf/10-02.pdf	NOUN
aji-31	327	7	http://www.modelsofcare.ca/pdf/10-02.pdf	http://www.modelsofcare.ca/pdf/10-02.pdf	NOUN
aji-31	327	8	https://www.shutterstock.com/image-vector/osteoarthritis-arthritis-pain-within-joint-degenerative-219992428	https://www.shutterstock.com/image-vector/osteoarthritis-arthritis-pain-within-joint-degenerative-219992428	NOUN
aji-31	327	9	https://www.shutterstock.com/image-vector/osteoarthritis-arthritis-pain-within-joint-degenerative-219992428	https://www.shutterstock.com/image-vector/osteoarthritis-arthritis-pain-within-joint-degenerative-219992428	NOUN
aji-31	327	10	https://www.shutterstock.com/image-vector/osteoarthritis-arthritis-pain-within-joint-degenerative-219992428	https://www.shutterstock.com/image-vector/osteoarthritis-arthritis-pain-within-joint-degenerative-219992428	NOUN
aji-31	327	11	https://teachmesurgery.com/orthopaedic/principles/osteoarthritis/	https://teachmesurgery.com/orthopaedic/principles/osteoarthritis/	PUNCT
aji-31	328	1	https://teachmesurgery.com/orthopaedic/principles/osteoarthritis/	https://teachmesurgery.com/orthopaedic/principles/osteoarthritis/	PROPN
aji-31	328	2	shehu	shehu	PROPN
aji-31	328	3	et	et	PROPN
aji-31	328	4	al	al	PROPN
aji-31	328	5	.	.	PROPN
aji-31	329	1	;	;	PUNCT
aji-31	329	2	aji	aji	PROPN
aji-31	329	3	,	,	PUNCT
aji-31	329	4	3(1	3(1	NUM
aji-31	329	5	):	):	PUNCT
aji-31	329	6	223	223	NUM
aji-31	329	7	-	-	SYM
aji-31	329	8	232	232	NUM
aji-31	329	9	,	,	PUNCT
aji-31	329	10	2020	2020	NUM
aji-31	329	11	;	;	PUNCT
aji-31	329	12	article	article	NOUN
aji-31	329	13	no.aji.57637	no.aji.57637	ADV
aji-31	329	14	231	231	NUM
aji-31	329	15	26	26	NUM
aji-31	329	16	.	.	PUNCT
aji-31	329	17	braun	braun	PROPN
aji-31	329	18	hj	hj	PROPN
aji-31	329	19	,	,	PUNCT
aji-31	329	20	gold	gold	PROPN
aji-31	329	21	ge	ge	PROPN
aji-31	329	22	.	.	PUNCT
aji-31	330	1	diagnosis	diagnosis	NOUN
aji-31	330	2	of	of	ADP
aji-31	330	3	osteoarthritis	osteoarthritis	NOUN
aji-31	330	4	:	:	PUNCT
aji-31	330	5	imaging	imaging	NOUN
aji-31	330	6	.	.	PUNCT
aji-31	331	1	bone	bone	NOUN
aji-31	331	2	.	.	PUNCT
aji-31	332	1	2012;51(2	2012;51(2	NUM
aji-31	332	2	):	):	PUNCT
aji-31	332	3	278	278	NUM
aji-31	332	4	-	-	SYM
aji-31	332	5	288	288	NUM
aji-31	332	6	.	.	PUNCT
aji-31	333	1	doi	doi	NOUN
aji-31	333	2	:	:	PUNCT
aji-31	333	3	10.1016	10.1016	NUM
aji-31	333	4	/	/	SYM
aji-31	333	5	j.bone.2011.11.019	j.bone.2011.11.019	PROPN
aji-31	333	6	27	27	NUM
aji-31	333	7	.	.	PUNCT
aji-31	334	1	guermazi	guermazi	PROPN
aji-31	334	2	a	a	PRON
aji-31	334	3	,	,	PUNCT
aji-31	334	4	roemer	roemer	PROPN
aji-31	334	5	fw	fw	PROPN
aji-31	334	6	,	,	PUNCT
aji-31	334	7	genant	genant	PROPN
aji-31	334	8	hk	hk	PROPN
aji-31	334	9	.	.	PUNCT
aji-31	335	1	role	role	NOUN
aji-31	335	2	of	of	ADP
aji-31	335	3	imaging	imaging	NOUN
aji-31	335	4	in	in	ADP
aji-31	335	5	osteoarthritis	osteoarthritis	NOUN
aji-31	335	6	:	:	PUNCT
aji-31	335	7	diagnosis	diagnosis	NOUN
aji-31	335	8	,	,	PUNCT
aji-31	335	9	prognosis	prognosis	NOUN
aji-31	335	10	and	and	CCONJ
aji-31	335	11	follow	follow	VERB
aji-31	335	12	-	-	PUNCT
aji-31	335	13	up	up	NOUN
aji-31	335	14	.	.	PUNCT
aji-31	336	1	medicographia	medicographia	X
aji-31	336	2	.	.	PUNCT
aji-31	337	1	2013;35:164	2013;35:164	NOUN
aji-31	337	2	-	-	SYM
aji-31	337	3	171	171	NUM
aji-31	337	4	.	.	PUNCT
aji-31	338	1	28	28	NUM
aji-31	338	2	.	.	PUNCT
aji-31	339	1	katz	katz	PROPN
aji-31	339	2	jn	jn	PROPN
aji-31	339	3	,	,	PUNCT
aji-31	339	4	brownlee	brownlee	PROPN
aji-31	339	5	sa	sa	PROPN
aji-31	339	6	,	,	PUNCT
aji-31	339	7	jones	jones	PROPN
aji-31	339	8	mh	mh	PROPN
aji-31	339	9	.	.	PUNCT
aji-31	340	1	the	the	DET
aji-31	340	2	role	role	NOUN
aji-31	340	3	of	of	ADP
aji-31	340	4	arthroscopy	arthroscopy	NOUN
aji-31	340	5	in	in	ADP
aji-31	340	6	the	the	DET
aji-31	340	7	management	management	NOUN
aji-31	340	8	of	of	ADP
aji-31	340	9	knee	knee	NOUN
aji-31	340	10	osteoarthritis	osteoarthritis	NOUN
aji-31	340	11	.	.	PUNCT
aji-31	341	1	best	good	ADJ
aji-31	341	2	pract	pract	PROPN
aji-31	341	3	res	re	NOUN
aji-31	341	4	clin	clin	PROPN
aji-31	341	5	rheumatol	rheumatol	NOUN
aji-31	341	6	.	.	PUNCT
aji-31	342	1	2014;28(1):143	2014;28(1):143	NUM
aji-31	342	2	-	-	PUNCT
aji-31	342	3	156	156	NUM
aji-31	342	4	.	.	PUNCT
aji-31	343	1	doi	doi	NOUN
aji-31	343	2	:	:	PUNCT
aji-31	343	3	10.1016	10.1016	NUM
aji-31	343	4	/	/	SYM
aji-31	343	5	j.berh.2014.01.008	j.berh.2014.01.008	PROPN
aji-31	343	6	29	29	NUM
aji-31	343	7	.	.	PUNCT
aji-31	344	1	oo	oo	INTJ
aji-31	344	2	wm	wm	PROPN
aji-31	344	3	,	,	PUNCT
aji-31	344	4	bo	bo	PROPN
aji-31	344	5	mt	mt	PROPN
aji-31	344	6	.	.	PROPN
aji-31	345	1	role	role	NOUN
aji-31	345	2	of	of	ADP
aji-31	345	3	ultrasonography	ultrasonography	NOUN
aji-31	345	4	in	in	ADP
aji-31	345	5	knee	knee	NOUN
aji-31	345	6	osteoarthritis	osteoarthritis	NOUN
aji-31	345	7	.	.	PUNCT
aji-31	346	1	j	j	PROPN
aji-31	346	2	clin	clin	PROPN
aji-31	346	3	rheumatol	rheumatol	NOUN
aji-31	346	4	.	.	PUNCT
aji-31	347	1	2016;22(6):324	2016;22(6):324	NUM
aji-31	347	2	-	-	PUNCT
aji-31	347	3	329	329	NUM
aji-31	347	4	.	.	PUNCT
aji-31	348	1	doi	doi	NOUN
aji-31	348	2	:	:	PUNCT
aji-31	348	3	10.1097	10.1097	NUM
aji-31	348	4	/	/	SYM
aji-31	348	5	rhu.0000000000000436	rhu.0000000000000436	NUM
aji-31	348	6	30	30	NUM
aji-31	348	7	.	.	PUNCT
aji-31	349	1	verbruggen	verbruggen	NOUN
aji-31	349	2	g	g	PROPN
aji-31	349	3	,	,	PUNCT
aji-31	349	4	wittoek	wittoek	ADJ
aji-31	349	5	r	r	NOUN
aji-31	349	6	,	,	PUNCT
aji-31	349	7	vander	vander	NOUN
aji-31	349	8	cruyssen	cruyssen	PROPN
aji-31	349	9	b	b	PROPN
aji-31	349	10	,	,	PUNCT
aji-31	349	11	elewaut	elewaut	PROPN
aji-31	349	12	d.	d.	PROPN
aji-31	349	13	tumour	tumour	NOUN
aji-31	349	14	necrosis	necrosis	NOUN
aji-31	349	15	factor	factor	NOUN
aji-31	349	16	blockade	blockade	NOUN
aji-31	349	17	for	for	ADP
aji-31	349	18	the	the	DET
aji-31	349	19	treatment	treatment	NOUN
aji-31	349	20	of	of	ADP
aji-31	349	21	erosive	erosive	ADJ
aji-31	349	22	osteoarthritis	osteoarthritis	NOUN
aji-31	349	23	of	of	ADP
aji-31	349	24	the	the	DET
aji-31	349	25	interphalangeal	interphalangeal	ADJ
aji-31	349	26	finger	finger	NOUN
aji-31	349	27	joints	joint	NOUN
aji-31	349	28	:	:	PUNCT
aji-31	349	29	a	a	DET
aji-31	349	30	double	double	ADJ
aji-31	349	31	blind	blind	ADJ
aji-31	349	32	,	,	PUNCT
aji-31	349	33	randomised	randomise	VERB
aji-31	349	34	trial	trial	NOUN
aji-31	349	35	on	on	ADP
aji-31	349	36	structure	structure	NOUN
aji-31	349	37	modification	modification	NOUN
aji-31	349	38	.	.	PUNCT
aji-31	350	1	ann	ann	PROPN
aji-31	350	2	rheum	rheum	PROPN
aji-31	350	3	dis	dis	PROPN
aji-31	350	4	.	.	PUNCT
aji-31	351	1	2012;71(6):891	2012;71(6):891	NUM
aji-31	351	2	-	-	SYM
aji-31	351	3	898	898	NUM
aji-31	351	4	.	.	PUNCT
aji-31	352	1	doi	doi	NOUN
aji-31	352	2	:	:	PUNCT
aji-31	352	3	10.1136	10.1136	NUM
aji-31	352	4	/	/	SYM
aji-31	352	5	ard.2011.149849	ard.2011.149849	PROPN
aji-31	352	6	31	31	NUM
aji-31	352	7	.	.	PUNCT
aji-31	353	1	chevalier	chevalier	NOUN
aji-31	353	2	x	x	PROPN
aji-31	353	3	,	,	PUNCT
aji-31	353	4	ravaud	ravaud	NOUN
aji-31	353	5	p	p	NOUN
aji-31	353	6	,	,	PUNCT
aji-31	353	7	maheu	maheu	ADJ
aji-31	353	8	e	e	NOUN
aji-31	353	9	,	,	PUNCT
aji-31	353	10	et	et	PROPN
aji-31	353	11	al	al	PROPN
aji-31	353	12	;	;	PUNCT
aji-31	353	13	french	french	ADJ
aji-31	353	14	section	section	NOUN
aji-31	353	15	of	of	ADP
aji-31	353	16	osteoarthritis	osteoarthritis	PROPN
aji-31	353	17	.	.	PUNCT
aji-31	354	1	adalimumab	adalimumab	PROPN
aji-31	354	2	in	in	ADP
aji-31	354	3	patients	patient	NOUN
aji-31	354	4	with	with	ADP
aji-31	354	5	hand	hand	NOUN
aji-31	354	6	osteoarthritis	osteoarthritis	NOUN
aji-31	354	7	refractory	refractory	NOUN
aji-31	354	8	to	to	ADP
aji-31	354	9	analgesics	analgesic	NOUN
aji-31	354	10	and	and	CCONJ
aji-31	354	11	nsaids	nsaid	NOUN
aji-31	354	12	:	:	PUNCT
aji-31	354	13	a	a	DET
aji-31	354	14	randomised	randomised	ADJ
aji-31	354	15	,	,	PUNCT
aji-31	354	16	multicentre	multicentre	ADJ
aji-31	354	17	,	,	PUNCT
aji-31	354	18	double	double	ADJ
aji-31	354	19	-	-	PUNCT
aji-31	354	20	blind	blind	ADJ
aji-31	354	21	,	,	PUNCT
aji-31	354	22	placebo	placebo	NOUN
aji-31	354	23	-	-	PUNCT
aji-31	354	24	controlled	control	VERB
aji-31	354	25	trial	trial	NOUN
aji-31	354	26	.	.	PUNCT
aji-31	355	1	ann	ann	PROPN
aji-31	355	2	rheum	rheum	PROPN
aji-31	355	3	dis	dis	PROPN
aji-31	355	4	.	.	PUNCT
aji-31	356	1	2015;74(9):1697	2015;74(9):1697	NUM
aji-31	356	2	-	-	SYM
aji-31	356	3	1705	1705	NUM
aji-31	356	4	.	.	PUNCT
aji-31	357	1	doi	doi	NOUN
aji-31	357	2	:	:	PUNCT
aji-31	357	3	10.1136	10.1136	NUM
aji-31	357	4	/	/	SYM
aji-31	357	5	annrheumdis-2014	annrheumdis-2014	NOUN
aji-31	357	6	-	-	PUNCT
aji-31	357	7	205348	205348	NUM
aji-31	357	8	32	32	NUM
aji-31	357	9	.	.	PUNCT
aji-31	358	1	martel	martel	NOUN
aji-31	358	2	-	-	PUNCT
aji-31	358	3	pelletier	pelletier	PROPN
aji-31	358	4	j	j	PROPN
aji-31	358	5	,	,	PUNCT
aji-31	358	6	pelletier	pelletier	PROPN
aji-31	358	7	jp	jp	PROPN
aji-31	358	8	.	.	PUNCT
aji-31	358	9	effects	effect	NOUN
aji-31	358	10	of	of	ADP
aji-31	358	11	diacerein	diacerein	ADJ
aji-31	358	12	at	at	ADP
aji-31	358	13	the	the	DET
aji-31	358	14	molecular	molecular	ADJ
aji-31	358	15	level	level	NOUN
aji-31	358	16	in	in	ADP
aji-31	358	17	the	the	DET
aji-31	358	18	osteoarthritis	osteoarthritis	NOUN
aji-31	358	19	disease	disease	NOUN
aji-31	358	20	process	process	NOUN
aji-31	358	21	.	.	PUNCT
aji-31	359	1	ther	ther	INTJ
aji-31	359	2	adv	adv	INTJ
aji-31	360	1	musculoskelet	musculoskelet	NOUN
aji-31	360	2	dis	dis	PROPN
aji-31	360	3	.	.	PUNCT
aji-31	361	1	2010;2(2):95	2010;2(2):95	NUM
aji-31	361	2	-	-	SYM
aji-31	361	3	104	104	NUM
aji-31	361	4	.	.	PUNCT
aji-31	362	1	doi	doi	NOUN
aji-31	362	2	:	:	PUNCT
aji-31	362	3	10.1177/1759720x09359104	10.1177/1759720x09359104	PROPN
aji-31	362	4	33	33	NUM
aji-31	362	5	.	.	PUNCT
aji-31	363	1	pavelka	pavelka	PROPN
aji-31	363	2	k	k	PROPN
aji-31	363	3	,	,	PUNCT
aji-31	363	4	trč	trč	PROPN
aji-31	363	5	t	t	PROPN
aji-31	363	6	,	,	PUNCT
aji-31	363	7	karpaš	karpaš	PROPN
aji-31	363	8	k	k	PROPN
aji-31	363	9	,	,	PUNCT
aji-31	363	10	et	et	PROPN
aji-31	363	11	al	al	PROPN
aji-31	363	12	.	.	PUNCT
aji-31	364	1	the	the	DET
aji-31	364	2	efficacy	efficacy	NOUN
aji-31	364	3	and	and	CCONJ
aji-31	364	4	safety	safety	NOUN
aji-31	364	5	of	of	ADP
aji-31	364	6	diacerein	diacerein	ADJ
aji-31	364	7	in	in	ADP
aji-31	364	8	the	the	DET
aji-31	364	9	treatment	treatment	NOUN
aji-31	364	10	of	of	ADP
aji-31	364	11	painful	painful	ADJ
aji-31	364	12	osteoarthritis	osteoarthritis	NOUN
aji-31	364	13	of	of	ADP
aji-31	364	14	the	the	DET
aji-31	364	15	knee	knee	NOUN
aji-31	364	16	:	:	PUNCT
aji-31	364	17	a	a	DET
aji-31	364	18	randomized	randomized	ADJ
aji-31	364	19	,	,	PUNCT
aji-31	364	20	multicenter	multicenter	NOUN
aji-31	364	21	,	,	PUNCT
aji-31	364	22	doubleblind	doubleblind	NOUN
aji-31	364	23	,	,	PUNCT
aji-31	364	24	placebo	placebo	NOUN
aji-31	364	25	-	-	PUNCT
aji-31	364	26	controlled	control	VERB
aji-31	364	27	study	study	NOUN
aji-31	364	28	with	with	ADP
aji-31	364	29	primary	primary	ADJ
aji-31	364	30	end	end	NOUN
aji-31	364	31	points	point	NOUN
aji-31	364	32	at	at	ADP
aji-31	364	33	two	two	NUM
aji-31	364	34	months	month	NOUN
aji-31	364	35	after	after	ADP
aji-31	364	36	the	the	DET
aji-31	364	37	end	end	NOUN
aji-31	364	38	of	of	ADP
aji-31	364	39	a	a	DET
aji-31	364	40	three	three	NUM
aji-31	364	41	-	-	PUNCT
aji-31	364	42	month	month	NOUN
aji-31	364	43	treatment	treatment	NOUN
aji-31	364	44	period	period	NOUN
aji-31	364	45	.	.	PUNCT
aji-31	365	1	arthritis	arthritis	NOUN
aji-31	365	2	rheum	rheum	NOUN
aji-31	365	3	.	.	PUNCT
aji-31	366	1	2007;56(12):4055	2007;56(12):4055	NUM
aji-31	366	2	-	-	SYM
aji-31	366	3	4064	4064	NUM
aji-31	366	4	.	.	PUNCT
aji-31	367	1	doi	doi	NOUN
aji-31	367	2	:	:	PUNCT
aji-31	367	3	10.1002	10.1002	NUM
aji-31	367	4	/	/	SYM
aji-31	367	5	art.23056	art.23056	PROPN
aji-31	367	6	34	34	NUM
aji-31	367	7	.	.	PUNCT
aji-31	367	8	fidelix	fidelix	PROPN
aji-31	367	9	ts	ts	PROPN
aji-31	367	10	,	,	PUNCT
aji-31	367	11	macedo	macedo	PROPN
aji-31	367	12	cr	cr	PROPN
aji-31	367	13	,	,	PUNCT
aji-31	367	14	maxwell	maxwell	PROPN
aji-31	367	15	lj	lj	PROPN
aji-31	367	16	,	,	PUNCT
aji-31	367	17	fernandes	fernandes	PROPN
aji-31	367	18	moça	moça	PROPN
aji-31	367	19	trevisani	trevisani	PROPN
aji-31	368	1	v.	v.	CCONJ
aji-31	368	2	diacerein	diacerein	ADV
aji-31	368	3	for	for	ADP
aji-31	368	4	osteoarthritis	osteoarthritis	NOUN
aji-31	368	5	.	.	PUNCT
aji-31	369	1	cochrane	cochrane	PROPN
aji-31	369	2	database	database	PROPN
aji-31	369	3	syst	syst	PROPN
aji-31	369	4	rev	rev	PROPN
aji-31	369	5	.	.	PROPN
aji-31	370	1	2014;(2):cd005117	2014;(2):cd005117	NUM
aji-31	370	2	.	.	X
aji-31	370	3	35	35	NUM
aji-31	370	4	.	.	X
aji-31	370	5	calich	calich	PROPN
aji-31	370	6	al	al	PROPN
aji-31	370	7	,	,	PUNCT
aji-31	370	8	domiciano	domiciano	ADJ
aji-31	370	9	ds	ds	ADJ
aji-31	370	10	,	,	PUNCT
aji-31	370	11	fuller	full	ADJ
aji-31	370	12	r.	r.	PROPN
aji-31	370	13	osteoarthritis	osteoarthritis	PROPN
aji-31	370	14	:	:	PUNCT
aji-31	370	15	can	can	AUX
aji-31	370	16	anti	anti	ADJ
aji-31	370	17	-	-	ADJ
aji-31	370	18	cytokine	cytokine	ADJ
aji-31	370	19	therapy	therapy	NOUN
aji-31	370	20	play	play	VERB
aji-31	370	21	a	a	DET
aji-31	370	22	role	role	NOUN
aji-31	370	23	in	in	ADP
aji-31	370	24	treatment	treatment	NOUN
aji-31	370	25	?	?	PUNCT
aji-31	371	1	clin	clin	PROPN
aji-31	371	2	rheumatol	rheumatol	NOUN
aji-31	371	3	.	.	PUNCT
aji-31	372	1	2010;29(5):451	2010;29(5):451	NUM
aji-31	372	2	-	-	SYM
aji-31	372	3	455	455	NUM
aji-31	372	4	.	.	PUNCT
aji-31	373	1	doi	doi	NOUN
aji-31	373	2	:	:	PUNCT
aji-31	373	3	10.1007	10.1007	NUM
aji-31	373	4	/	/	SYM
aji-31	373	5	s10067	s10067	NOUN
aji-31	373	6	-	-	PUNCT
aji-31	373	7	009	009	NUM
aji-31	373	8	-	-	PUNCT
aji-31	373	9	1352	1352	NUM
aji-31	373	10	-	-	SYM
aji-31	373	11	3	3	NUM
aji-31	373	12	36	36	NUM
aji-31	373	13	.	.	PUNCT
aji-31	374	1	scoville	scoville	PROPN
aji-31	374	2	cd	cd	PROPN
aji-31	374	3	,	,	PUNCT
aji-31	374	4	dickson	dickson	PROPN
aji-31	374	5	jp	jp	PROPN
aji-31	374	6	.	.	PUNCT
aji-31	374	7	open	open	ADJ
aji-31	374	8	-	-	PUNCT
aji-31	374	9	label	label	NOUN
aji-31	374	10	use	use	NOUN
aji-31	374	11	of	of	ADP
aji-31	374	12	anakinra	anakinra	NOUN
aji-31	374	13	(	(	PUNCT
aji-31	374	14	kineret	kineret	NOUN
aji-31	374	15	)	)	PUNCT
aji-31	374	16	in	in	ADP
aji-31	374	17	the	the	DET
aji-31	374	18	treatment	treatment	NOUN
aji-31	374	19	of	of	ADP
aji-31	374	20	patients	patient	NOUN
aji-31	374	21	with	with	ADP
aji-31	374	22	osteoarthritis	osteoarthritis	NOUN
aji-31	374	23	.	.	PUNCT
aji-31	375	1	indian	indian	PROPN
aji-31	375	2	j	j	PROPN
aji-31	375	3	rheumatol	rheumatol	NOUN
aji-31	375	4	.	.	PUNCT
aji-31	376	1	2017;12(1):17	2017;12(1):17	NUM
aji-31	376	2	-	-	SYM
aji-31	376	3	22	22	NUM
aji-31	376	4	.	.	PUNCT
aji-31	377	1	doi	doi	NOUN
aji-31	377	2	:	:	PUNCT
aji-31	377	3	10.4103/0973	10.4103/0973	NUM
aji-31	377	4	-	-	SYM
aji-31	377	5	3698.199125	3698.199125	NUM
aji-31	377	6	37	37	NUM
aji-31	377	7	.	.	PUNCT
aji-31	378	1	perkins	perkins	PROPN
aji-31	378	2	k	k	PROPN
aji-31	378	3	,	,	PUNCT
aji-31	378	4	sahy	sahy	VERB
aji-31	378	5	w	w	PROPN
aji-31	378	6	,	,	PUNCT
aji-31	378	7	beckett	beckett	PROPN
aji-31	378	8	rd	rd	PROPN
aji-31	378	9	.	.	PROPN
aji-31	379	1	efficacy	efficacy	NOUN
aji-31	379	2	of	of	ADP
aji-31	379	3	curcuma	curcuma	NOUN
aji-31	379	4	for	for	ADP
aji-31	379	5	treatment	treatment	NOUN
aji-31	379	6	of	of	ADP
aji-31	379	7	osteoarthritis	osteoarthritis	NOUN
aji-31	379	8	.	.	PUNCT
aji-31	380	1	j	j	PROPN
aji-31	380	2	evid	evid	PROPN
aji-31	380	3	based	base	VERB
aji-31	380	4	complementary	complementary	ADJ
aji-31	380	5	altern	altern	NOUN
aji-31	380	6	med	me	VERB
aji-31	380	7	.	.	PUNCT
aji-31	381	1	2017;22(1):156	2017;22(1):156	NUM
aji-31	381	2	-	-	PUNCT
aji-31	381	3	165	165	NUM
aji-31	381	4	.	.	PUNCT
aji-31	381	5	doi	doi	NOUN
aji-31	381	6	:	:	PUNCT
aji-31	381	7	10.1177/2156587216636747	10.1177/2156587216636747	NUM
aji-31	381	8	38	38	NUM
aji-31	381	9	.	.	PUNCT
aji-31	382	1	kuptniratsaikul	kuptniratsaikul	PROPN
aji-31	382	2	v	v	ADP
aji-31	382	3	,	,	PUNCT
aji-31	382	4	dajpratham	dajpratham	PROPN
aji-31	382	5	p	p	NOUN
aji-31	382	6	,	,	PUNCT
aji-31	382	7	taechaarpornkul	taechaarpornkul	ADJ
aji-31	382	8	w	w	PROPN
aji-31	382	9	,	,	PUNCT
aji-31	382	10	et	et	PROPN
aji-31	382	11	al	al	PROPN
aji-31	382	12	.	.	PROPN
aji-31	382	13	efficacy	efficacy	NOUN
aji-31	382	14	and	and	CCONJ
aji-31	382	15	safety	safety	NOUN
aji-31	382	16	of	of	ADP
aji-31	382	17	curcuma	curcuma	PROPN
aji-31	382	18	domestica	domestica	PROPN
aji-31	382	19	extracts	extract	NOUN
aji-31	382	20	compared	compare	VERB
aji-31	382	21	with	with	ADP
aji-31	382	22	ibuprofen	ibuprofen	NOUN
aji-31	382	23	in	in	ADP
aji-31	382	24	patients	patient	NOUN
aji-31	382	25	with	with	ADP
aji-31	382	26	knee	knee	NOUN
aji-31	382	27	osteoarthritis	osteoarthritis	NOUN
aji-31	382	28	:	:	PUNCT
aji-31	382	29	a	a	DET
aji-31	382	30	multicenter	multicenter	ADJ
aji-31	382	31	study	study	NOUN
aji-31	382	32	.	.	PUNCT
aji-31	383	1	clin	clin	PROPN
aji-31	383	2	interv	interv	VERB
aji-31	383	3	aging	age	VERB
aji-31	383	4	.	.	PUNCT
aji-31	384	1	2014;9:451	2014;9:451	NUM
aji-31	384	2	-	-	SYM
aji-31	384	3	458	458	NUM
aji-31	384	4	.	.	PUNCT
aji-31	385	1	doi	doi	NOUN
aji-31	385	2	:	:	PUNCT
aji-31	385	3	10.2147	10.2147	NUM
aji-31	385	4	/	/	SYM
aji-31	385	5	cia.s58535	cia.s58535	NOUN
aji-31	385	6	39	39	NUM
aji-31	385	7	.	.	PUNCT
aji-31	386	1	pinsornsak	pinsornsak	PROPN
aji-31	386	2	p	p	NOUN
aji-31	386	3	,	,	PUNCT
aji-31	386	4	niempoog	niempoog	PROPN
aji-31	386	5	s.	s.	PROPN
aji-31	386	6	the	the	DET
aji-31	386	7	efficacy	efficacy	NOUN
aji-31	386	8	of	of	ADP
aji-31	386	9	curcuma	curcuma	PROPN
aji-31	386	10	longa	longa	PROPN
aji-31	386	11	l.	l.	PROPN
aji-31	386	12	extract	extract	PROPN
aji-31	386	13	as	as	ADP
aji-31	386	14	an	an	DET
aji-31	386	15	adjuvant	adjuvant	ADJ
aji-31	386	16	therapy	therapy	NOUN
aji-31	386	17	in	in	ADP
aji-31	386	18	primary	primary	ADJ
aji-31	386	19	knee	knee	NOUN
aji-31	386	20	osteoarthritis	osteoarthritis	NOUN
aji-31	386	21	:	:	PUNCT
aji-31	386	22	a	a	DET
aji-31	386	23	randomized	randomized	ADJ
aji-31	386	24	control	control	NOUN
aji-31	386	25	trial	trial	NOUN
aji-31	386	26	.	.	PUNCT
aji-31	387	1	j	j	PROPN
aji-31	387	2	med	med	PROPN
aji-31	387	3	assoc	assoc	PROPN
aji-31	387	4	thai	thai	PROPN
aji-31	387	5	.	.	PUNCT
aji-31	388	1	2012;95(suppl	2012;95(suppl	NOUN
aji-31	388	2	1):s51	1):s51	NOUN
aji-31	388	3	-	-	PUNCT
aji-31	388	4	s58	s58	ADJ
aji-31	388	5	.	.	PUNCT
aji-31	389	1	40	40	NUM
aji-31	389	2	.	.	PUNCT
aji-31	390	1	nakagawa	nakagawa	PROPN
aji-31	390	2	y	y	PROPN
aji-31	390	3	,	,	PUNCT
aji-31	390	4	mukai	mukai	PROPN
aji-31	390	5	s	s	PROPN
aji-31	390	6	,	,	PUNCT
aji-31	390	7	yamada	yamada	PROPN
aji-31	390	8	s	s	PROPN
aji-31	390	9	,	,	PUNCT
aji-31	390	10	et	et	PROPN
aji-31	390	11	al	al	PROPN
aji-31	390	12	.	.	PUNCT
aji-31	390	13	short	short	ADJ
aji-31	390	14	-	-	PUNCT
aji-31	390	15	term	term	NOUN
aji-31	390	16	effects	effect	NOUN
aji-31	390	17	of	of	ADP
aji-31	390	18	highly	highly	ADV
aji-31	390	19	-	-	PUNCT
aji-31	390	20	bioavailable	bioavailable	ADJ
aji-31	390	21	curcumin	curcumin	NOUN
aji-31	390	22	for	for	ADP
aji-31	390	23	treating	treat	VERB
aji-31	390	24	knee	knee	NOUN
aji-31	390	25	osteoarthritis	osteoarthritis	NOUN
aji-31	390	26	:	:	PUNCT
aji-31	390	27	a	a	DET
aji-31	390	28	randomized	randomized	ADJ
aji-31	390	29	,	,	PUNCT
aji-31	390	30	double	double	ADJ
aji-31	390	31	-	-	PUNCT
aji-31	390	32	blind	blind	ADJ
aji-31	390	33	,	,	PUNCT
aji-31	390	34	placebocontrolled	placebocontrolle	VERB
aji-31	390	35	prospective	prospective	ADJ
aji-31	390	36	study	study	NOUN
aji-31	390	37	.	.	PUNCT
aji-31	391	1	j	j	PROPN
aji-31	391	2	orthop	orthop	PROPN
aji-31	391	3	sci	sci	PROPN
aji-31	391	4	.	.	PUNCT
aji-31	392	1	2014;19(6):933	2014;19(6):933	PROPN
aji-31	392	2	-	-	PUNCT
aji-31	392	3	939	939	PROPN
aji-31	392	4	.	.	PUNCT
aji-31	393	1	doi	doi	NOUN
aji-31	393	2	:	:	PUNCT
aji-31	393	3	10.1007	10.1007	NUM
aji-31	393	4	/	/	SYM
aji-31	393	5	s00776	s00776	NOUN
aji-31	393	6	-	-	PUNCT
aji-31	393	7	014	014	NUM
aji-31	393	8	-	-	PUNCT
aji-31	393	9	0633	0633	NUM
aji-31	393	10	-	-	SYM
aji-31	393	11	0	0	NUM
aji-31	393	12	41	41	NUM
aji-31	393	13	.	.	PUNCT
aji-31	394	1	belcaro	belcaro	NOUN
aji-31	394	2	g	g	PROPN
aji-31	394	3	,	,	PUNCT
aji-31	394	4	cesarone	cesarone	NOUN
aji-31	394	5	mr	mr	PROPN
aji-31	394	6	,	,	PUNCT
aji-31	394	7	dugall	dugall	PROPN
aji-31	394	8	m	m	PROPN
aji-31	394	9	,	,	PUNCT
aji-31	394	10	et	et	PROPN
aji-31	394	11	al	al	PROPN
aji-31	394	12	.	.	PROPN
aji-31	394	13	efficacy	efficacy	NOUN
aji-31	394	14	and	and	CCONJ
aji-31	394	15	safety	safety	NOUN
aji-31	394	16	of	of	ADP
aji-31	394	17	meriva	meriva	PROPN
aji-31	394	18	®	®	PROPN
aji-31	394	19	,	,	PUNCT
aji-31	394	20	a	a	DET
aji-31	394	21	curcuminphosphatidylcholine	curcuminphosphatidylcholine	NOUN
aji-31	394	22	complex	complex	NOUN
aji-31	394	23	,	,	PUNCT
aji-31	394	24	during	during	ADP
aji-31	394	25	extended	extended	ADJ
aji-31	394	26	administration	administration	NOUN
aji-31	394	27	in	in	ADP
aji-31	394	28	osteoarthritis	osteoarthritis	NOUN
aji-31	394	29	patients	patient	NOUN
aji-31	394	30	.	.	PUNCT
aji-31	395	1	altern	altern	PROPN
aji-31	395	2	med	med	PROPN
aji-31	395	3	rev	rev	PROPN
aji-31	395	4	.	.	PUNCT
aji-31	396	1	2010;15(4):337344	2010;15(4):337344	NUM
aji-31	396	2	.	.	PUNCT
aji-31	397	1	42	42	NUM
aji-31	397	2	.	.	PUNCT
aji-31	398	1	kizhakkedath	kizhakkedath	PROPN
aji-31	398	2	r.	r.	PROPN
aji-31	398	3	clinical	clinical	PROPN
aji-31	398	4	evaluation	evaluation	NOUN
aji-31	398	5	of	of	ADP
aji-31	398	6	a	a	DET
aji-31	398	7	formulation	formulation	NOUN
aji-31	398	8	containing	contain	VERB
aji-31	398	9	curcuma	curcuma	PROPN
aji-31	398	10	longa	longa	NOUN
aji-31	398	11	and	and	CCONJ
aji-31	398	12	boswellia	boswellia	VERB
aji-31	398	13	serrata	serrata	ADJ
aji-31	398	14	extracts	extract	NOUN
aji-31	398	15	in	in	ADP
aji-31	398	16	the	the	DET
aji-31	398	17	management	management	NOUN
aji-31	398	18	of	of	ADP
aji-31	398	19	knee	knee	NOUN
aji-31	398	20	osteoarthritis	osteoarthritis	NOUN
aji-31	398	21	.	.	PUNCT
aji-31	399	1	mol	mol	ADP
aji-31	399	2	med	med	PROPN
aji-31	399	3	rep	rep	PROPN
aji-31	399	4	.	.	PROPN
aji-31	399	5	2013;8(5):1542	2013;8(5):1542	NUM
aji-31	399	6	-	-	SYM
aji-31	399	7	1548	1548	NUM
aji-31	399	8	.	.	PUNCT
aji-31	400	1	doi	doi	NOUN
aji-31	400	2	:	:	PUNCT
aji-31	400	3	10.3892	10.3892	NUM
aji-31	400	4	/	/	SYM
aji-31	400	5	mmr.2013.1661	mmr.2013.1661	PROPN
aji-31	400	6	43	43	NUM
aji-31	400	7	.	.	PUNCT
aji-31	401	1	xing	xing	PROPN
aji-31	401	2	rl	rl	PROPN
aji-31	401	3	,	,	PUNCT
aji-31	401	4	zhao	zhao	PROPN
aji-31	401	5	lr	lr	PROPN
aji-31	401	6	,	,	PUNCT
aji-31	401	7	wang	wang	PROPN
aji-31	401	8	pm	pm	PROPN
aji-31	401	9	.	.	PUNCT
aji-31	402	1	bisphosphonates	bisphosphonate	NOUN
aji-31	402	2	therapy	therapy	NOUN
aji-31	402	3	for	for	ADP
aji-31	402	4	osteoarthritis	osteoarthritis	NOUN
aji-31	402	5	:	:	PUNCT
aji-31	402	6	a	a	DET
aji-31	402	7	meta	meta	ADJ
aji-31	402	8	-	-	PUNCT
aji-31	402	9	analysis	analysis	NOUN
aji-31	402	10	of	of	ADP
aji-31	402	11	randomized	randomized	ADJ
aji-31	402	12	controlled	control	VERB
aji-31	402	13	trials	trial	NOUN
aji-31	402	14	.	.	PUNCT
aji-31	403	1	springerplus	springerplus	PROPN
aji-31	403	2	.	.	PUNCT
aji-31	404	1	2016;5(1):1704	2016;5(1):1704	X
aji-31	404	2	.	.	PUNCT
aji-31	405	1	doi	doi	NOUN
aji-31	405	2	:	:	PUNCT
aji-31	405	3	10.1186	10.1186	NUM
aji-31	405	4	/	/	SYM
aji-31	405	5	s40064	s40064	PROPN
aji-31	405	6	-	-	PUNCT
aji-31	405	7	016	016	NUM
aji-31	405	8	-	-	PUNCT
aji-31	405	9	3359	3359	NUM
aji-31	405	10	-	-	PUNCT
aji-31	405	11	y	y	PROPN
aji-31	405	12	44	44	NUM
aji-31	405	13	.	.	PUNCT
aji-31	406	1	sinaa	sinaa	PROPN
aji-31	406	2	abdul	abdul	PROPN
aji-31	406	3	amir	amir	PROPN
aji-31	406	4	kadhim	kadhim	PROPN
aji-31	406	5	,	,	PUNCT
aji-31	406	6	haidar	haidar	PROPN
aji-31	406	7	mahdi	mahdi	PROPN
aji-31	406	8	jawad	jawad	PROPN
aji-31	406	9	,	,	PUNCT
aji-31	406	10	sami	sami	PROPN
aji-31	406	11	salman	salman	PROPN
aji-31	406	12	shihab	shihab	PROPN
aji-31	406	13	.	.	PUNCT
aji-31	407	1	alendronate	alendronate	PROPN
aji-31	407	2	sodium	sodium	NOUN
aji-31	407	3	in	in	ADP
aji-31	407	4	osteoarthritis	osteoarthritis	NOUN
aji-31	407	5	:	:	PUNCT
aji-31	407	6	effects	effect	NOUN
aji-31	407	7	on	on	ADP
aji-31	407	8	lipid	lipid	NOUN
aji-31	407	9	profile	profile	NOUN
aji-31	407	10	,	,	PUNCT
aji-31	407	11	circulating	circulate	VERB
aji-31	407	12	leptin	leptin	NOUN
aji-31	407	13	and	and	CCONJ
aji-31	407	14	the	the	DET
aji-31	407	15	clinical	clinical	ADJ
aji-31	407	16	activity	activity	NOUN
aji-31	407	17	.	.	PUNCT
aji-31	408	1	jmscr	jmscr	NOUN
aji-31	408	2	;	;	PUNCT
aji-31	408	3	2017	2017	NUM
aji-31	408	4	.	.	PUNCT
aji-31	409	1	45	45	NUM
aji-31	409	2	.	.	PUNCT
aji-31	410	1	bingham	bingham	PROPN
aji-31	410	2	co	co	PROPN
aji-31	410	3	iii	iii	PROPN
aji-31	410	4	,	,	PUNCT
aji-31	410	5	buckland	buckland	PROPN
aji-31	410	6	-	-	PUNCT
aji-31	410	7	wright	wright	PROPN
aji-31	410	8	jc	jc	PROPN
aji-31	410	9	,	,	PUNCT
aji-31	410	10	garnero	garnero	NOUN
aji-31	410	11	p	p	NOUN
aji-31	410	12	,	,	PUNCT
aji-31	410	13	et	et	PROPN
aji-31	410	14	al	al	PROPN
aji-31	410	15	.	.	PROPN
aji-31	410	16	risedronate	risedronate	PROPN
aji-31	410	17	decreases	decrease	VERB
aji-31	410	18	biochemical	biochemical	ADJ
aji-31	410	19	markers	marker	NOUN
aji-31	410	20	of	of	ADP
aji-31	410	21	cartilage	cartilage	NOUN
aji-31	410	22	degradation	degradation	NOUN
aji-31	410	23	but	but	CCONJ
aji-31	410	24	does	do	AUX
aji-31	410	25	not	not	PART
aji-31	410	26	decrease	decrease	VERB
aji-31	410	27	symptoms	symptom	NOUN
aji-31	410	28	or	or	CCONJ
aji-31	410	29	slow	slow	ADJ
aji-31	410	30	radiographic	radiographic	ADJ
aji-31	410	31	shehu	shehu	NOUN
aji-31	410	32	et	et	PROPN
aji-31	410	33	al	al	PROPN
aji-31	410	34	.	.	PROPN
aji-31	410	35	;	;	PUNCT
aji-31	410	36	aji	aji	PROPN
aji-31	410	37	,	,	PUNCT
aji-31	410	38	3(1	3(1	NUM
aji-31	410	39	):	):	PUNCT
aji-31	410	40	223	223	NUM
aji-31	410	41	-	-	SYM
aji-31	410	42	232	232	NUM
aji-31	410	43	,	,	PUNCT
aji-31	410	44	2020	2020	NUM
aji-31	410	45	;	;	PUNCT
aji-31	410	46	article	article	NOUN
aji-31	410	47	no.aji.57637	no.aji.57637	ADV
aji-31	410	48	232	232	NUM
aji-31	410	49	progression	progression	NOUN
aji-31	410	50	in	in	ADP
aji-31	410	51	patients	patient	NOUN
aji-31	410	52	with	with	ADP
aji-31	410	53	medial	medial	ADJ
aji-31	410	54	compartment	compartment	NOUN
aji-31	410	55	osteoarthritis	osteoarthritis	NOUN
aji-31	410	56	of	of	ADP
aji-31	410	57	the	the	DET
aji-31	410	58	knee	knee	NOUN
aji-31	410	59	:	:	PUNCT
aji-31	410	60	results	result	NOUN
aji-31	410	61	of	of	ADP
aji-31	410	62	the	the	DET
aji-31	410	63	two	two	NUM
aji-31	410	64	-	-	PUNCT
aji-31	410	65	year	year	NOUN
aji-31	410	66	multinational	multinational	ADJ
aji-31	410	67	knee	knee	NOUN
aji-31	410	68	osteoarthritis	osteoarthritis	PROPN
aji-31	410	69	structural	structural	ADJ
aji-31	410	70	arthritis	arthritis	NOUN
aji-31	410	71	study	study	NOUN
aji-31	410	72	.	.	PUNCT
aji-31	411	1	arthritis	arthritis	NOUN
aji-31	411	2	rheum	rheum	NOUN
aji-31	411	3	.	.	PUNCT
aji-31	412	1	2006;54(11):3494	2006;54(11):3494	NUM
aji-31	412	2	-	-	SYM
aji-31	412	3	3507	3507	NUM
aji-31	412	4	.	.	PUNCT
aji-31	413	1	doi	doi	NOUN
aji-31	413	2	:	:	PUNCT
aji-31	413	3	10.1002	10.1002	NUM
aji-31	413	4	/	/	SYM
aji-31	413	5	art.22160	art.22160	PROPN
aji-31	413	6	46	46	NUM
aji-31	413	7	.	.	PUNCT
aji-31	414	1	laslett	laslett	PROPN
aji-31	414	2	ll	ll	PROPN
aji-31	414	3	,	,	PUNCT
aji-31	414	4	doré	doré	PROPN
aji-31	414	5	da	da	PROPN
aji-31	414	6	,	,	PUNCT
aji-31	414	7	quinn	quinn	NOUN
aji-31	414	8	sj	sj	PROPN
aji-31	414	9	,	,	PUNCT
aji-31	414	10	et	et	PROPN
aji-31	414	11	al	al	PROPN
aji-31	414	12	.	.	PROPN
aji-31	414	13	zoledronic	zoledronic	ADJ
aji-31	414	14	acid	acid	NOUN
aji-31	414	15	reduces	reduce	VERB
aji-31	414	16	knee	knee	NOUN
aji-31	414	17	pain	pain	NOUN
aji-31	414	18	and	and	CCONJ
aji-31	414	19	bone	bone	NOUN
aji-31	414	20	marrow	marrow	NOUN
aji-31	414	21	lesions	lesion	NOUN
aji-31	414	22	over	over	ADP
aji-31	414	23	1	1	NUM
aji-31	414	24	year	year	NOUN
aji-31	414	25	:	:	PUNCT
aji-31	414	26	a	a	DET
aji-31	414	27	randomised	randomised	ADJ
aji-31	414	28	controlled	control	VERB
aji-31	414	29	trial	trial	NOUN
aji-31	414	30	.	.	PUNCT
aji-31	415	1	ann	ann	PROPN
aji-31	415	2	rheum	rheum	PROPN
aji-31	415	3	dis	dis	PROPN
aji-31	415	4	.	.	PUNCT
aji-31	416	1	2012;71(8):1322	2012;71(8):1322	PROPN
aji-31	416	2	-	-	PROPN
aji-31	416	3	1328	1328	NUM
aji-31	416	4	.	.	PUNCT
aji-31	417	1	doi	doi	NOUN
aji-31	417	2	:	:	PUNCT
aji-31	417	3	10.1136	10.1136	NUM
aji-31	417	4	/	/	SYM
aji-31	417	5	annrheumdis-2011	annrheumdis-2011	NOUN
aji-31	417	6	-	-	PUNCT
aji-31	417	7	200970	200970	NUM
aji-31	417	8	47	47	NUM
aji-31	417	9	.	.	PUNCT
aji-31	418	1	meunier	meunier	PROPN
aji-31	418	2	pj	pj	PROPN
aji-31	418	3	,	,	PUNCT
aji-31	418	4	roux	roux	NOUN
aji-31	418	5	c	c	NOUN
aji-31	418	6	,	,	PUNCT
aji-31	418	7	seeman	seeman	PROPN
aji-31	418	8	e	e	PROPN
aji-31	418	9	,	,	PUNCT
aji-31	418	10	et	et	PROPN
aji-31	418	11	al	al	PROPN
aji-31	418	12	.	.	PUNCT
aji-31	419	1	the	the	DET
aji-31	419	2	effects	effect	NOUN
aji-31	419	3	of	of	ADP
aji-31	419	4	strontium	strontium	NOUN
aji-31	419	5	ranelate	ranelate	NOUN
aji-31	419	6	on	on	ADP
aji-31	419	7	the	the	DET
aji-31	419	8	risk	risk	NOUN
aji-31	419	9	of	of	ADP
aji-31	419	10	vertebral	vertebral	ADJ
aji-31	419	11	fracture	fracture	NOUN
aji-31	419	12	in	in	ADP
aji-31	419	13	women	woman	NOUN
aji-31	419	14	with	with	ADP
aji-31	419	15	postmenopausal	postmenopausal	ADJ
aji-31	419	16	osteoporosis	osteoporosis	NOUN
aji-31	419	17	.	.	PUNCT
aji-31	420	1	n	n	CCONJ
aji-31	420	2	engl	engl	PROPN
aji-31	420	3	j	j	PROPN
aji-31	420	4	med	med	PROPN
aji-31	420	5	.	.	PUNCT
aji-31	421	1	2004;350(5):459	2004;350(5):459	NUM
aji-31	421	2	-	-	SYM
aji-31	421	3	468	468	NUM
aji-31	421	4	.	.	PUNCT
aji-31	421	5	doi	doi	NOUN
aji-31	421	6	:	:	PUNCT
aji-31	421	7	10.1056	10.1056	NUM
aji-31	421	8	/	/	SYM
aji-31	421	9	nejmoa022436	nejmoa022436	PROPN
aji-31	421	10	48	48	NUM
aji-31	421	11	.	.	PUNCT
aji-31	422	1	reginster	reginster	PROPN
aji-31	422	2	jy	jy	PROPN
aji-31	422	3	,	,	PUNCT
aji-31	422	4	badurski	badurski	PROPN
aji-31	422	5	j	j	PROPN
aji-31	422	6	,	,	PUNCT
aji-31	422	7	bellamy	bellamy	PROPN
aji-31	422	8	n	n	CCONJ
aji-31	422	9	,	,	PUNCT
aji-31	422	10	et	et	PROPN
aji-31	422	11	al	al	PROPN
aji-31	422	12	.	.	PROPN
aji-31	422	13	efficacy	efficacy	NOUN
aji-31	422	14	and	and	CCONJ
aji-31	422	15	safety	safety	NOUN
aji-31	422	16	of	of	ADP
aji-31	422	17	strontium	strontium	NOUN
aji-31	422	18	ranelate	ranelate	NOUN
aji-31	422	19	in	in	ADP
aji-31	422	20	the	the	DET
aji-31	422	21	treatment	treatment	NOUN
aji-31	422	22	of	of	ADP
aji-31	422	23	knee	knee	NOUN
aji-31	422	24	osteoarthritis	osteoarthritis	NOUN
aji-31	422	25	:	:	PUNCT
aji-31	422	26	results	result	NOUN
aji-31	422	27	of	of	ADP
aji-31	422	28	a	a	DET
aji-31	422	29	double	double	ADJ
aji-31	422	30	-	-	PUNCT
aji-31	422	31	blind	blind	ADJ
aji-31	422	32	,	,	PUNCT
aji-31	422	33	randomised	randomise	VERB
aji-31	422	34	placebo	placebo	NOUN
aji-31	422	35	-	-	PUNCT
aji-31	422	36	controlled	control	VERB
aji-31	422	37	trial	trial	NOUN
aji-31	422	38	.	.	PUNCT
aji-31	423	1	ann	ann	PROPN
aji-31	423	2	rheum	rheum	PROPN
aji-31	423	3	dis	dis	PROPN
aji-31	423	4	.	.	PUNCT
aji-31	424	1	2013;72(2):179	2013;72(2):179	PROPN
aji-31	424	2	-	-	SYM
aji-31	424	3	186	186	NUM
aji-31	424	4	.	.	PUNCT
aji-31	425	1	doi	doi	NOUN
aji-31	425	2	:	:	PUNCT
aji-31	425	3	10.1136	10.1136	NUM
aji-31	425	4	/	/	SYM
aji-31	425	5	annrheumdis-2012	annrheumdis-2012	NOUN
aji-31	425	6	-	-	PUNCT
aji-31	425	7	202231	202231	NUM
aji-31	425	8	49	49	NUM
aji-31	425	9	.	.	PUNCT
aji-31	426	1	yu	yu	PROPN
aji-31	426	2	dg	dg	PROPN
aji-31	426	3	,	,	PUNCT
aji-31	426	4	ding	ding	NOUN
aji-31	426	5	hf	hf	ADP
aji-31	426	6	,	,	PUNCT
aji-31	426	7	mao	mao	PROPN
aji-31	426	8	yq	yq	PROPN
aji-31	426	9	,	,	PUNCT
aji-31	426	10	et	et	PROPN
aji-31	426	11	al	al	PROPN
aji-31	426	12	.	.	PROPN
aji-31	426	13	strontium	strontium	NOUN
aji-31	426	14	ranelate	ranelate	NOUN
aji-31	426	15	reduces	reduce	VERB
aji-31	426	16	cartilage	cartilage	NOUN
aji-31	426	17	degeneration	degeneration	NOUN
aji-31	426	18	and	and	CCONJ
aji-31	426	19	subchondral	subchondral	ADJ
aji-31	426	20	bone	bone	NOUN
aji-31	426	21	remodeling	remodeling	NOUN
aji-31	426	22	in	in	ADP
aji-31	426	23	rat	rat	NOUN
aji-31	426	24	osteoarthritis	osteoarthritis	NOUN
aji-31	426	25	model	model	NOUN
aji-31	426	26	.	.	PUNCT
aji-31	427	1	acta	acta	PROPN
aji-31	427	2	pharmacol	pharmacol	PROPN
aji-31	427	3	sin	sin	NOUN
aji-31	427	4	.	.	PUNCT
aji-31	428	1	2013;34(3):393	2013;34(3):393	NUM
aji-31	428	2	-	-	PUNCT
aji-31	428	3	402	402	NUM
aji-31	428	4	.	.	PUNCT
aji-31	428	5	doi	doi	NOUN
aji-31	428	6	:	:	PUNCT
aji-31	428	7	10.1038	10.1038	NUM
aji-31	428	8	/	/	SYM
aji-31	428	9	aps.2012.167	aps.2012.167	ADJ
aji-31	428	10	50	50	NUM
aji-31	428	11	.	.	PUNCT
aji-31	429	1	morita	morita	PROPN
aji-31	429	2	m	m	PROPN
aji-31	429	3	,	,	PUNCT
aji-31	429	4	yamada	yamada	PROPN
aji-31	429	5	k	k	PROPN
aji-31	429	6	,	,	PUNCT
aji-31	429	7	date	date	NOUN
aji-31	429	8	h	h	NOUN
aji-31	429	9	,	,	PUNCT
aji-31	429	10	hayakawa	hayakawa	PROPN
aji-31	429	11	k	k	PROPN
aji-31	429	12	,	,	PUNCT
aji-31	429	13	sakurai	sakurai	PROPN
aji-31	429	14	h	h	PROPN
aji-31	429	15	,	,	PUNCT
aji-31	429	16	yamada	yamada	PROPN
aji-31	429	17	h.	h.	PROPN
aji-31	429	18	efficacy	efficacy	PROPN
aji-31	429	19	of	of	ADP
aji-31	429	20	chondroitin	chondroitin	NOUN
aji-31	429	21	sulfate	sulfate	NOUN
aji-31	429	22	for	for	ADP
aji-31	429	23	painful	painful	ADJ
aji-31	429	24	knee	knee	NOUN
aji-31	429	25	osteoarthritis	osteoarthritis	NOUN
aji-31	429	26	:	:	PUNCT
aji-31	429	27	a	a	PRON
aji-31	429	28	one	one	NUM
aji-31	429	29	-	-	PUNCT
aji-31	429	30	year	year	NOUN
aji-31	429	31	,	,	PUNCT
aji-31	429	32	randomized	randomize	VERB
aji-31	429	33	,	,	PUNCT
aji-31	429	34	double	double	ADJ
aji-31	429	35	-	-	PUNCT
aji-31	429	36	blind	blind	ADJ
aji-31	429	37	,	,	PUNCT
aji-31	429	38	multicenter	multicenter	ADJ
aji-31	429	39	clinical	clinical	ADJ
aji-31	429	40	study	study	NOUN
aji-31	429	41	in	in	ADP
aji-31	429	42	japan	japan	PROPN
aji-31	429	43	.	.	PUNCT
aji-31	430	1	biol	biol	PROPN
aji-31	430	2	pharm	pharm	PROPN
aji-31	430	3	bull	bull	PROPN
aji-31	430	4	.	.	PUNCT
aji-31	431	1	2018;41(2	2018;41(2	NUM
aji-31	431	2	):	):	PUNCT
aji-31	431	3	163‐171	163‐171	NUM
aji-31	431	4	.	.	PUNCT
aji-31	432	1	doi	doi	NOUN
aji-31	432	2	:	:	PUNCT
aji-31	432	3	10.1248	10.1248	NUM
aji-31	432	4	/	/	SYM
aji-31	432	5	bpb.b17	bpb.b17	NOUN
aji-31	432	6	-	-	PUNCT
aji-31	432	7	00556	00556	NUM
aji-31	432	8	51	51	NUM
aji-31	432	9	.	.	PUNCT
aji-31	433	1	pelletier	pelletier	PROPN
aji-31	433	2	jp	jp	PROPN
aji-31	433	3	,	,	PUNCT
aji-31	433	4	raynauld	raynauld	AUX
aji-31	433	5	jp	jp	NOUN
aji-31	433	6	,	,	PUNCT
aji-31	433	7	beaulieu	beaulieu	NOUN
aji-31	433	8	ad	ad	NOUN
aji-31	433	9	,	,	PUNCT
aji-31	433	10	et	et	PROPN
aji-31	433	11	al	al	PROPN
aji-31	433	12	.	.	PROPN
aji-31	433	13	chondroitin	chondroitin	PROPN
aji-31	433	14	sulfate	sulfate	NOUN
aji-31	433	15	efficacy	efficacy	NOUN
aji-31	433	16	versus	versus	ADP
aji-31	433	17	celecoxib	celecoxib	VERB
aji-31	433	18	on	on	ADP
aji-31	433	19	knee	knee	NOUN
aji-31	433	20	osteoarthritis	osteoarthritis	NOUN
aji-31	433	21	structural	structural	ADJ
aji-31	433	22	changes	change	NOUN
aji-31	433	23	using	use	VERB
aji-31	433	24	magnetic	magnetic	ADJ
aji-31	433	25	resonance	resonance	NOUN
aji-31	433	26	imaging	imaging	NOUN
aji-31	433	27	:	:	PUNCT
aji-31	433	28	a	a	DET
aji-31	433	29	2	2	NUM
aji-31	433	30	-	-	PUNCT
aji-31	433	31	year	year	NOUN
aji-31	433	32	multicentre	multicentre	NOUN
aji-31	433	33	exploratory	exploratory	ADJ
aji-31	433	34	study	study	NOUN
aji-31	433	35	.	.	PUNCT
aji-31	434	1	arthritis	arthritis	NOUN
aji-31	434	2	res	re	NOUN
aji-31	434	3	ther	ther	ADV
aji-31	434	4	.	.	PUNCT
aji-31	435	1	2016;18(1):256	2016;18(1):256	PROPN
aji-31	435	2	.	.	PUNCT
aji-31	436	1	published	publish	VERB
aji-31	436	2	2016	2016	NUM
aji-31	436	3	nov	nov	PROPN
aji-31	436	4	3	3	NUM
aji-31	436	5	.	.	PUNCT
aji-31	436	6	doi	doi	NOUN
aji-31	436	7	:	:	PUNCT
aji-31	436	8	10.1186	10.1186	NUM
aji-31	436	9	/	/	SYM
aji-31	436	10	s13075	s13075	NUM
aji-31	436	11	-	-	PUNCT
aji-31	436	12	016	016	NUM
aji-31	436	13	-	-	PUNCT
aji-31	436	14	1149	1149	NUM
aji-31	436	15	-	-	SYM
aji-31	436	16	0	0	NUM
aji-31	436	17	52	52	NUM
aji-31	436	18	.	.	PUNCT
aji-31	437	1	zhu	zhu	PROPN
aji-31	437	2	x	x	PUNCT
aji-31	437	3	,	,	PUNCT
aji-31	437	4	sang	sing	VERB
aji-31	437	5	l	l	NOUN
aji-31	437	6	,	,	PUNCT
aji-31	438	1	wu	wu	PROPN
aji-31	438	2	d	d	PROPN
aji-31	438	3	,	,	PUNCT
aji-31	438	4	rong	rong	PROPN
aji-31	438	5	j	j	PROPN
aji-31	438	6	,	,	PUNCT
aji-31	438	7	jiang	jiang	PROPN
aji-31	438	8	l.	l.	PROPN
aji-31	438	9	effectiveness	effectiveness	PROPN
aji-31	438	10	and	and	CCONJ
aji-31	438	11	safety	safety	NOUN
aji-31	438	12	of	of	ADP
aji-31	438	13	glucosamine	glucosamine	NOUN
aji-31	438	14	and	and	CCONJ
aji-31	438	15	chondroitin	chondroitin	NOUN
aji-31	438	16	for	for	ADP
aji-31	438	17	the	the	DET
aji-31	438	18	treatment	treatment	NOUN
aji-31	438	19	of	of	ADP
aji-31	438	20	osteoarthritis	osteoarthritis	NOUN
aji-31	438	21	:	:	PUNCT
aji-31	438	22	a	a	DET
aji-31	438	23	meta	meta	ADJ
aji-31	438	24	-	-	PUNCT
aji-31	438	25	analysis	analysis	NOUN
aji-31	438	26	of	of	ADP
aji-31	438	27	randomized	randomized	ADJ
aji-31	438	28	controlled	control	VERB
aji-31	438	29	trials	trial	NOUN
aji-31	438	30	.	.	PUNCT
aji-31	439	1	j	j	PROPN
aji-31	439	2	orthop	orthop	PROPN
aji-31	439	3	surg	surg	NOUN
aji-31	439	4	res	re	NOUN
aji-31	439	5	.	.	PUNCT
aji-31	440	1	2018;13(1):170	2018;13(1):170	NUM
aji-31	440	2	.	.	PUNCT
aji-31	441	1	published	publish	VERB
aji-31	441	2	2018	2018	NUM
aji-31	441	3	jul	jul	PROPN
aji-31	441	4	6	6	NUM
aji-31	441	5	doi	doi	NOUN
aji-31	441	6	:	:	PUNCT
aji-31	441	7	10.1186	10.1186	NUM
aji-31	441	8	/	/	SYM
aji-31	441	9	s13018	s13018	PROPN
aji-31	441	10	-	-	PUNCT
aji-31	441	11	018	018	NUM
aji-31	441	12	-	-	PUNCT
aji-31	441	13	0871	0871	NUM
aji-31	441	14	-	-	SYM
aji-31	441	15	5	5	NUM
aji-31	441	16	53	53	NUM
aji-31	441	17	.	.	PUNCT
aji-31	442	1	bhandari	bhandari	PROPN
aji-31	442	2	m	m	PROPN
aji-31	442	3	,	,	PUNCT
aji-31	442	4	bannuru	bannuru	PROPN
aji-31	442	5	rr	rr	PROPN
aji-31	442	6	,	,	PUNCT
aji-31	442	7	babins	babin	VERB
aji-31	442	8	em	em	PRON
aji-31	442	9	,	,	PUNCT
aji-31	442	10	et	et	PROPN
aji-31	442	11	al	al	PROPN
aji-31	442	12	.	.	PUNCT
aji-31	443	1	intra	intra	ADJ
aji-31	443	2	-	-	ADJ
aji-31	443	3	articular	articular	ADJ
aji-31	443	4	hyaluronic	hyaluronic	ADJ
aji-31	443	5	acid	acid	NOUN
aji-31	443	6	in	in	ADP
aji-31	443	7	the	the	DET
aji-31	443	8	treatment	treatment	NOUN
aji-31	443	9	of	of	ADP
aji-31	443	10	knee	knee	NOUN
aji-31	443	11	osteoarthritis	osteoarthritis	NOUN
aji-31	443	12	:	:	PUNCT
aji-31	443	13	a	a	DET
aji-31	443	14	canadian	canadian	ADJ
aji-31	443	15	evidence	evidence	NOUN
aji-31	443	16	-	-	PUNCT
aji-31	443	17	based	base	VERB
aji-31	443	18	perspective	perspective	NOUN
aji-31	443	19	.	.	PUNCT
aji-31	444	1	published	publish	VERB
aji-31	444	2	correction	correction	NOUN
aji-31	444	3	appears	appear	VERB
aji-31	444	4	in	in	ADP
aji-31	444	5	ther	ther	ADV
aji-31	444	6	adv	adv	INTJ
aji-31	444	7	musculoskelet	musculoskelet	NOUN
aji-31	444	8	dis	dis	PROPN
aji-31	444	9	.	.	PUNCT
aji-31	445	1	2017;9(11):295	2017;9(11):295	PROPN
aji-31	445	2	.	.	PUNCT
aji-31	446	1	ther	ther	PROPN
aji-31	446	2	adv	adv	INTJ
aji-31	446	3	musculoskelet	musculoskelet	NOUN
aji-31	446	4	dis	dis	PROPN
aji-31	446	5	.	.	PUNCT
aji-31	447	1	2017;9(9):231‐246	2017;9(9):231‐246	NUM
aji-31	447	2	.	.	PUNCT
aji-31	448	1	doi	doi	NOUN
aji-31	448	2	:	:	PUNCT
aji-31	448	3	10.1177/1759720x17729641	10.1177/1759720x17729641	PROPN
aji-31	448	4	54	54	NUM
aji-31	448	5	.	.	PUNCT
aji-31	449	1	baron	baron	PROPN
aji-31	449	2	d	d	PROPN
aji-31	449	3	,	,	PUNCT
aji-31	449	4	flin	flin	PROPN
aji-31	449	5	c	c	PROPN
aji-31	449	6	,	,	PUNCT
aji-31	449	7	porterie	porterie	PROPN
aji-31	449	8	j	j	PROPN
aji-31	449	9	,	,	PUNCT
aji-31	449	10	despaux	despaux	PROPN
aji-31	449	11	j	j	PROPN
aji-31	449	12	,	,	PUNCT
aji-31	449	13	vincent	vincent	PROPN
aji-31	449	14	p.	p.	PROPN
aji-31	449	15	hyaluronic	hyaluronic	PROPN
aji-31	449	16	acid	acid	ADJ
aji-31	449	17	single	single	ADJ
aji-31	449	18	intraarticular	intraarticular	NOUN
aji-31	449	19	injection	injection	NOUN
aji-31	449	20	in	in	ADP
aji-31	449	21	knee	knee	NOUN
aji-31	449	22	osteoarthritis	osteoarthritis	NOUN
aji-31	449	23	:	:	PUNCT
aji-31	449	24	a	a	DET
aji-31	449	25	multicenter	multicenter	NOUN
aji-31	449	26	open	open	ADJ
aji-31	449	27	prospective	prospective	ADJ
aji-31	449	28	study	study	NOUN
aji-31	449	29	(	(	PUNCT
aji-31	449	30	artone	artone	NOUN
aji-31	449	31	75	75	NUM
aji-31	449	32	)	)	PUNCT
aji-31	449	33	with	with	ADP
aji-31	449	34	placebo	placebo	NOUN
aji-31	449	35	post	post	X
aji-31	449	36	hoc	hoc	X
aji-31	449	37	comparison	comparison	NOUN
aji-31	449	38	.	.	PUNCT
aji-31	450	1	curr	curr	PROPN
aji-31	450	2	ther	ther	PROPN
aji-31	450	3	res	re	VERB
aji-31	450	4	clin	clin	PROPN
aji-31	450	5	exp	exp	PROPN
aji-31	450	6	.	.	PUNCT
aji-31	451	1	2018;88:35‐46	2018;88:35‐46	NUM
aji-31	451	2	.	.	PUNCT
aji-31	452	1	published	publish	VERB
aji-31	452	2	2018	2018	NUM
aji-31	452	3	apr	apr	PROPN
aji-31	452	4	18	18	NUM
aji-31	452	5	doi	doi	NOUN
aji-31	452	6	:	:	PUNCT
aji-31	452	7	10.1016	10.1016	NUM
aji-31	452	8	/	/	SYM
aji-31	452	9	j.curtheres.2018.04.001	j.curtheres.2018.04.001	PROPN
aji-31	452	10	55	55	NUM
aji-31	452	11	.	.	PUNCT
aji-31	452	12	bruyère	bruyère	PROPN
aji-31	453	1	o	o	PROPN
aji-31	453	2	,	,	PUNCT
aji-31	453	3	altman	altman	PROPN
aji-31	453	4	rd	rd	PROPN
aji-31	453	5	,	,	PUNCT
aji-31	453	6	reginster	reginster	PROPN
aji-31	453	7	jy	jy	PROPN
aji-31	453	8	.	.	PROPN
aji-31	453	9	efficacy	efficacy	NOUN
aji-31	453	10	and	and	CCONJ
aji-31	453	11	safety	safety	NOUN
aji-31	453	12	of	of	ADP
aji-31	453	13	glucosamine	glucosamine	NOUN
aji-31	453	14	sulfate	sulfate	NOUN
aji-31	453	15	in	in	ADP
aji-31	453	16	the	the	DET
aji-31	453	17	management	management	NOUN
aji-31	453	18	of	of	ADP
aji-31	453	19	osteoarthritis	osteoarthritis	NOUN
aji-31	453	20	:	:	PUNCT
aji-31	453	21	evidence	evidence	NOUN
aji-31	453	22	from	from	ADP
aji-31	453	23	real	real	ADJ
aji-31	453	24	-	-	PUNCT
aji-31	453	25	life	life	NOUN
aji-31	453	26	setting	set	VERB
aji-31	453	27	trials	trial	NOUN
aji-31	453	28	and	and	CCONJ
aji-31	453	29	surveys	survey	NOUN
aji-31	453	30	.	.	PUNCT
aji-31	454	1	semin	semin	PROPN
aji-31	454	2	arthritis	arthritis	PROPN
aji-31	454	3	rheum	rheum	PROPN
aji-31	454	4	.	.	PUNCT
aji-31	455	1	2016	2016	NUM
aji-31	455	2	;	;	PUNCT
aji-31	455	3	45(4	45(4	NUM
aji-31	455	4	suppl):s12‐s17	suppl):s12‐s17	NOUN
aji-31	455	5	.	.	PUNCT
aji-31	456	1	doi	doi	NOUN
aji-31	456	2	:	:	PUNCT
aji-31	456	3	10.1016	10.1016	NUM
aji-31	456	4	/	/	SYM
aji-31	456	5	j.semarthrit.2015.11.011	j.semarthrit.2015.11.011	PROPN
aji-31	457	1	56	56	NUM
aji-31	457	2	.	.	PUNCT
aji-31	457	3	reginster	reginster	PROPN
aji-31	457	4	jy	jy	PROPN
aji-31	457	5	,	,	PUNCT
aji-31	457	6	neuprez	neuprez	NOUN
aji-31	457	7	a	a	PRON
aji-31	457	8	,	,	PUNCT
aji-31	457	9	lecart	lecart	PROPN
aji-31	457	10	mp	mp	PROPN
aji-31	457	11	,	,	PUNCT
aji-31	457	12	sarlet	sarlet	NOUN
aji-31	457	13	n	n	CCONJ
aji-31	457	14	,	,	PUNCT
aji-31	457	15	bruyere	bruyere	NOUN
aji-31	457	16	o.	o.	ADJ
aji-31	457	17	role	role	NOUN
aji-31	457	18	of	of	ADP
aji-31	457	19	glucosamine	glucosamine	NOUN
aji-31	457	20	in	in	ADP
aji-31	457	21	the	the	DET
aji-31	457	22	treatment	treatment	NOUN
aji-31	457	23	for	for	ADP
aji-31	457	24	osteoarthritis	osteoarthritis	NOUN
aji-31	457	25	.	.	PUNCT
aji-31	458	1	rheumatol	rheumatol	PROPN
aji-31	458	2	int	int	PROPN
aji-31	458	3	.	.	PUNCT
aji-31	459	1	2012;32(10):2959‐2967	2012;32(10):2959‐2967	PROPN
aji-31	459	2	.	.	PUNCT
aji-31	459	3	doi	doi	NOUN
aji-31	459	4	:	:	PUNCT
aji-31	459	5	10.1007	10.1007	NUM
aji-31	459	6	/	/	SYM
aji-31	459	7	s00296	s00296	PROPN
aji-31	459	8	-	-	PUNCT
aji-31	459	9	012	012	NUM
aji-31	459	10	-	-	PUNCT
aji-31	459	11	2416	2416	NUM
aji-31	459	12	-	-	SYM
aji-31	459	13	2	2	NUM
aji-31	459	14	_	_	PUNCT
aji-31	459	15	_	_	PUNCT
aji-31	460	1	_	_	PUNCT
aji-31	461	1	_	_	PUNCT
aji-31	462	1	_	_	PUNCT
aji-31	463	1	_	_	PUNCT
aji-31	464	1	_	_	PUNCT
aji-31	465	1	_	_	PUNCT
aji-31	466	1	_	_	PUNCT
aji-31	467	1	_	_	PUNCT
aji-31	468	1	_	_	PUNCT
aji-31	469	1	_	_	PUNCT
aji-31	470	1	_	_	PUNCT
aji-31	471	1	_	_	PUNCT
aji-31	472	1	_	_	PUNCT
aji-31	473	1	_	_	PUNCT
aji-31	474	1	_	_	PUNCT
aji-31	475	1	_	_	PUNCT
aji-31	476	1	_	_	PUNCT
aji-31	477	1	_	_	PUNCT
aji-31	478	1	_	_	PUNCT
aji-31	479	1	_	_	PUNCT
aji-31	480	1	_	_	PUNCT
aji-31	481	1	_	_	PUNCT
aji-31	482	1	_	_	PUNCT
aji-31	483	1	_	_	PUNCT
aji-31	484	1	_	_	PUNCT
aji-31	485	1	_	_	PUNCT
aji-31	486	1	_	_	PUNCT
aji-31	487	1	_	_	PUNCT
aji-31	488	1	_	_	PUNCT
aji-31	489	1	_	_	PUNCT
aji-31	490	1	_	_	PUNCT
aji-31	491	1	_	_	PUNCT
aji-31	492	1	_	_	PUNCT
aji-31	493	1	_	_	PUNCT
aji-31	494	1	_	_	PUNCT
aji-31	495	1	_	_	PUNCT
aji-31	496	1	_	_	PUNCT
aji-31	497	1	_	_	PUNCT
aji-31	498	1	_	_	PUNCT
aji-31	499	1	_	_	PUNCT
aji-31	500	1	_	_	PUNCT
aji-31	501	1	_	_	PUNCT
aji-31	502	1	_	_	PUNCT
aji-31	503	1	_	_	PUNCT
aji-31	504	1	_	_	PUNCT
aji-31	505	1	_	_	PUNCT
aji-31	506	1	_	_	PUNCT
aji-31	507	1	_	_	PUNCT
aji-31	508	1	_	_	PUNCT
aji-31	509	1	_	_	PUNCT
aji-31	510	1	_	_	PUNCT
aji-31	511	1	_	_	PUNCT
aji-31	512	1	_	_	PUNCT
aji-31	513	1	_	_	PUNCT
aji-31	514	1	_	_	PUNCT
aji-31	515	1	_	_	PUNCT
aji-31	516	1	_	_	PUNCT
aji-31	517	1	_	_	PUNCT
aji-31	518	1	_	_	PUNCT
aji-31	519	1	_	_	PUNCT
aji-31	520	1	_	_	PUNCT
aji-31	521	1	_	_	PUNCT
aji-31	522	1	_	_	PUNCT
aji-31	523	1	_	_	PUNCT
aji-31	524	1	_	_	PUNCT
aji-31	525	1	_	_	PUNCT
aji-31	526	1	_	_	PUNCT
aji-31	527	1	_	_	PUNCT
aji-31	528	1	_	_	PUNCT
aji-31	529	1	_	_	PUNCT
aji-31	530	1	_	_	PUNCT
aji-31	531	1	_	_	PUNCT
aji-31	532	1	_	_	PUNCT
aji-31	533	1	_	_	PUNCT
aji-31	534	1	_	_	PUNCT
aji-31	535	1	_	_	PUNCT
aji-31	536	1	_	_	PUNCT
aji-31	537	1	_	_	PUNCT
aji-31	538	1	_	_	PUNCT
aji-31	539	1	©	©	ADP
aji-31	539	2	2020	2020	NUM
aji-31	539	3	shehu	shehu	NOUN
aji-31	539	4	et	et	PROPN
aji-31	539	5	al	al	PROPN
aji-31	539	6	.	.	PROPN
aji-31	539	7	;	;	PUNCT
aji-31	539	8	this	this	PRON
aji-31	539	9	is	be	AUX
aji-31	539	10	an	an	DET
aji-31	539	11	open	open	ADJ
aji-31	539	12	access	access	NOUN
aji-31	539	13	article	article	NOUN
aji-31	539	14	distributed	distribute	VERB
aji-31	539	15	under	under	ADP
aji-31	539	16	the	the	DET
aji-31	539	17	terms	term	NOUN
aji-31	539	18	of	of	ADP
aji-31	539	19	the	the	DET
aji-31	539	20	creative	creative	ADJ
aji-31	539	21	commons	common	NOUN
aji-31	539	22	attribution	attribution	NOUN
aji-31	539	23	license	license	NOUN
aji-31	539	24	(	(	PUNCT
aji-31	539	25	http://creativecommons.org/licenses/by/4.0	http://creativecommons.org/licenses/by/4.0	NOUN
aji-31	539	26	)	)	PUNCT
aji-31	539	27	,	,	PUNCT
aji-31	539	28	which	which	PRON
aji-31	539	29	permits	permit	VERB
aji-31	539	30	unrestricted	unrestricted	ADJ
aji-31	539	31	use	use	NOUN
aji-31	539	32	,	,	PUNCT
aji-31	539	33	distribution	distribution	NOUN
aji-31	539	34	,	,	PUNCT
aji-31	539	35	and	and	CCONJ
aji-31	539	36	reproduction	reproduction	NOUN
aji-31	539	37	in	in	ADP
aji-31	539	38	any	any	DET
aji-31	539	39	medium	medium	NOUN
aji-31	539	40	,	,	PUNCT
aji-31	539	41	provided	provide	VERB
aji-31	539	42	the	the	DET
aji-31	539	43	original	original	ADJ
aji-31	539	44	work	work	NOUN
aji-31	539	45	is	be	AUX
aji-31	539	46	properly	properly	ADV
aji-31	539	47	cited	cite	VERB
aji-31	539	48	.	.	PUNCT
aji-31	540	1	peer	peer	NOUN
aji-31	540	2	-	-	PUNCT
aji-31	540	3	review	review	NOUN
aji-31	540	4	history	history	NOUN
aji-31	540	5	:	:	PUNCT
aji-31	540	6	the	the	DET
aji-31	540	7	peer	peer	NOUN
aji-31	540	8	review	review	NOUN
aji-31	540	9	history	history	NOUN
aji-31	540	10	for	for	ADP
aji-31	540	11	this	this	DET
aji-31	540	12	paper	paper	NOUN
aji-31	540	13	can	can	AUX
aji-31	540	14	be	be	AUX
aji-31	540	15	accessed	access	VERB
aji-31	540	16	here	here	ADV
aji-31	540	17	:	:	PUNCT
aji-31	540	18	http://www.sdiarticle4.com/review-history/57637	http://www.sdiarticle4.com/review-history/57637	PROPN
aji-31	540	19	http://creativecommons.org/licenses/by/4.0	http://creativecommons.org/licenses/by/4.0	X