id	sid	tid	token	lemma	pos
aji-66	1	1	_	_	PUNCT
aji-66	2	1	_	_	PUNCT
aji-66	3	1	_	_	PUNCT
aji-66	4	1	_	_	PUNCT
aji-66	5	1	_	_	PUNCT
aji-66	6	1	_	_	PUNCT
aji-66	7	1	_	_	PUNCT
aji-66	8	1	_	_	PUNCT
aji-66	9	1	_	_	PUNCT
aji-66	10	1	_	_	PUNCT
aji-66	11	1	_	_	PUNCT
aji-66	12	1	_	_	PUNCT
aji-66	13	1	_	_	PUNCT
aji-66	14	1	_	_	PUNCT
aji-66	15	1	_	_	PUNCT
aji-66	16	1	_	_	PUNCT
aji-66	17	1	_	_	PUNCT
aji-66	18	1	_	_	PUNCT
aji-66	19	1	_	_	PUNCT
aji-66	20	1	_	_	PUNCT
aji-66	21	1	_	_	PUNCT
aji-66	22	1	_	_	PUNCT
aji-66	23	1	_	_	PUNCT
aji-66	24	1	_	_	PUNCT
aji-66	25	1	_	_	PUNCT
aji-66	26	1	_	_	PUNCT
aji-66	27	1	_	_	PUNCT
aji-66	28	1	_	_	PUNCT
aji-66	29	1	_	_	PUNCT
aji-66	30	1	_	_	PUNCT
aji-66	31	1	_	_	PUNCT
aji-66	32	1	_	_	PUNCT
aji-66	33	1	_	_	PUNCT
aji-66	34	1	_	_	PUNCT
aji-66	35	1	_	_	PUNCT
aji-66	36	1	_	_	PUNCT
aji-66	37	1	_	_	PUNCT
aji-66	38	1	_	_	PUNCT
aji-66	39	1	_	_	PUNCT
aji-66	40	1	_	_	PUNCT
aji-66	41	1	_	_	PUNCT
aji-66	42	1	_	_	PUNCT
aji-66	43	1	_	_	PUNCT
aji-66	44	1	_	_	PUNCT
aji-66	45	1	_	_	PUNCT
aji-66	46	1	_	_	PUNCT
aji-66	47	1	_	_	PUNCT
aji-66	48	1	_	_	PUNCT
aji-66	49	1	_	_	PUNCT
aji-66	50	1	_	_	PUNCT
aji-66	51	1	_	_	PUNCT
aji-66	52	1	_	_	PUNCT
aji-66	53	1	_	_	PUNCT
aji-66	54	1	_	_	PUNCT
aji-66	55	1	_	_	PUNCT
aji-66	56	1	_	_	PUNCT
aji-66	57	1	_	_	PUNCT
aji-66	58	1	_	_	PUNCT
aji-66	59	1	_	_	PUNCT
aji-66	60	1	_	_	PUNCT
aji-66	61	1	_	_	PUNCT
aji-66	62	1	_	_	PUNCT
aji-66	63	1	_	_	PUNCT
aji-66	64	1	_	_	PUNCT
aji-66	65	1	_	_	PUNCT
aji-66	66	1	_	_	PUNCT
aji-66	67	1	_	_	PUNCT
aji-66	68	1	_	_	PUNCT
aji-66	69	1	_	_	PUNCT
aji-66	70	1	_	_	PUNCT
aji-66	71	1	_	_	PUNCT
aji-66	72	1	_	_	PUNCT
aji-66	73	1	_	_	PUNCT
aji-66	74	1	_	_	PUNCT
aji-66	75	1	_	_	PUNCT
aji-66	76	1	_	_	PUNCT
aji-66	77	1	_	_	PUNCT
aji-66	78	1	_	_	PUNCT
aji-66	79	1	_	_	PUNCT
aji-66	80	1	_	_	PUNCT
aji-66	81	1	_	_	PUNCT
aji-66	82	1	_	_	PUNCT
aji-66	83	1	_	_	PUNCT
aji-66	84	1	_	_	PUNCT
aji-66	85	1	_	_	PUNCT
aji-66	86	1	_	_	PUNCT
aji-66	87	1	_	_	PUNCT
aji-66	88	1	_	_	PUNCT
aji-66	89	1	_	_	PUNCT
aji-66	90	1	_	_	PUNCT
aji-66	91	1	_	_	PUNCT
aji-66	92	1	_	_	PUNCT
aji-66	93	1	_	_	PUNCT
aji-66	94	1	_	_	PUNCT
aji-66	95	1	_	_	PUNCT
aji-66	96	1	_	_	PUNCT
aji-66	97	1	_	_	PUNCT
aji-66	98	1	_	_	PUNCT
aji-66	99	1	_	_	PUNCT
aji-66	100	1	_	_	PUNCT
aji-66	101	1	_	_	PUNCT
aji-66	102	1	*	*	PUNCT
aji-66	102	2	corresponding	correspond	VERB
aji-66	102	3	author	author	NOUN
aji-66	102	4	:	:	PUNCT
aji-66	102	5	e	e	NOUN
aji-66	102	6	-	-	NOUN
aji-66	102	7	mail	mail	NOUN
aji-66	102	8	:	:	PUNCT
aji-66	102	9	shadrackkimenju@gmail.com	shadrackkimenju@gmail.com	PROPN
aji-66	102	10	;	;	PUNCT
aji-66	102	11	asian	asian	ADJ
aji-66	102	12	journal	journal	NOUN
aji-66	102	13	of	of	ADP
aji-66	102	14	immunology	immunology	NOUN
aji-66	102	15	4(1	4(1	NOUN
aji-66	102	16	):	):	PUNCT
aji-66	102	17	77	77	NUM
aji-66	102	18	-	-	SYM
aji-66	102	19	84	84	NUM
aji-66	102	20	,	,	PUNCT
aji-66	102	21	2021	2021	NUM
aji-66	102	22	;	;	PUNCT
aji-66	102	23	article	article	NOUN
aji-66	102	24	no.aji.69854	no.aji.69854	NOUN
aji-66	102	25	advances	advance	VERB
aji-66	102	26	and	and	CCONJ
aji-66	102	27	challenges	challenge	NOUN
aji-66	102	28	in	in	ADP
aji-66	102	29	transmission	transmission	NOUN
aji-66	102	30	-	-	PUNCT
aji-66	102	31	blocking	block	VERB
aji-66	102	32	malaria	malaria	NOUN
aji-66	102	33	vaccine	vaccine	NOUN
aji-66	102	34	development	development	NOUN
aji-66	102	35	.	.	PUNCT
aji-66	103	1	a	a	DET
aji-66	103	2	systematic	systematic	ADJ
aji-66	103	3	review	review	NOUN
aji-66	103	4	laura	laura	PROPN
aji-66	103	5	nyawira	nyawira	PROPN
aji-66	103	6	wangai1	wangai1	PROPN
aji-66	103	7	,	,	PUNCT
aji-66	103	8	shadrack	shadrack	NOUN
aji-66	103	9	kimenju	kimenju	PROPN
aji-66	103	10	kahiro2	kahiro2	PROPN
aji-66	103	11	*	*	PROPN
aji-66	103	12	,	,	PUNCT
aji-66	103	13	kenny	kenny	PROPN
aji-66	103	14	kimani	kimani	PROPN
aji-66	103	15	kamau1	kamau1	PROPN
aji-66	103	16	,	,	PUNCT
aji-66	103	17	david	david	PROPN
aji-66	103	18	waweru	waweru	PROPN
aji-66	103	19	nderu1	nderu1	PROPN
aji-66	103	20	,	,	PUNCT
aji-66	103	21	immaculate	immaculate	ADJ
aji-66	103	22	marwa	marwa	PROPN
aji-66	103	23	nyaiseba1	nyaiseba1	PROPN
aji-66	103	24	,	,	PUNCT
aji-66	103	25	david	david	PROPN
aji-66	103	26	butto	butto	PROPN
aji-66	103	27	amarch1	amarch1	PROPN
aji-66	103	28	,	,	PUNCT
aji-66	103	29	mark	mark	PROPN
aji-66	103	30	kilongosi	kilongosi	PROPN
aji-66	103	31	webale1	webale1	NOUN
aji-66	103	32	and	and	CCONJ
aji-66	103	33	elly	elly	ADV
aji-66	103	34	munde1	munde1	NOUN
aji-66	103	35	1	1	NUM
aji-66	103	36	school	school	NOUN
aji-66	103	37	of	of	ADP
aji-66	103	38	health	health	NOUN
aji-66	103	39	sciences	sciences	PROPN
aji-66	103	40	,	,	PUNCT
aji-66	103	41	kirinyaga	kirinyaga	NOUN
aji-66	103	42	university	university	PROPN
aji-66	103	43	,	,	PUNCT
aji-66	103	44	kutus	kutus	PROPN
aji-66	103	45	,	,	PUNCT
aji-66	103	46	kenya	kenya	PROPN
aji-66	103	47	.	.	PUNCT
aji-66	104	1	2	2	NUM
aji-66	104	2	department	department	NOUN
aji-66	104	3	of	of	ADP
aji-66	104	4	biochemistry	biochemistry	NOUN
aji-66	104	5	,	,	PUNCT
aji-66	104	6	jomo	jomo	PROPN
aji-66	104	7	kenyatta	kenyatta	PROPN
aji-66	104	8	university	university	PROPN
aji-66	104	9	of	of	ADP
aji-66	104	10	agriculture	agriculture	NOUN
aji-66	104	11	and	and	CCONJ
aji-66	104	12	technology	technology	NOUN
aji-66	104	13	,	,	PUNCT
aji-66	104	14	p.o	p.o	PROPN
aji-66	104	15	.	.	PROPN
aji-66	104	16	box	box	PROPN
aji-66	104	17	62000	62000	NUM
aji-66	104	18	-	-	PUNCT
aji-66	104	19	00200	00200	NUM
aji-66	104	20	,	,	PUNCT
aji-66	104	21	nairobi	nairobi	PROPN
aji-66	104	22	,	,	PUNCT
aji-66	104	23	kenya	kenya	PROPN
aji-66	104	24	.	.	PUNCT
aji-66	105	1	authors	author	NOUN
aji-66	105	2	’	'	PUNCT
aji-66	105	3	contributions	contribution	NOUN
aji-66	105	4	this	this	DET
aji-66	105	5	work	work	NOUN
aji-66	105	6	was	be	AUX
aji-66	105	7	carried	carry	VERB
aji-66	105	8	out	out	ADP
aji-66	105	9	in	in	ADP
aji-66	105	10	collaboration	collaboration	NOUN
aji-66	105	11	among	among	ADP
aji-66	105	12	all	all	DET
aji-66	105	13	authors	author	NOUN
aji-66	105	14	.	.	PUNCT
aji-66	106	1	all	all	DET
aji-66	106	2	authors	author	NOUN
aji-66	106	3	read	read	VERB
aji-66	106	4	and	and	CCONJ
aji-66	106	5	approved	approve	VERB
aji-66	106	6	the	the	DET
aji-66	106	7	final	final	ADJ
aji-66	106	8	manuscript	manuscript	NOUN
aji-66	106	9	.	.	PUNCT
aji-66	107	1	article	article	NOUN
aji-66	107	2	information	information	PROPN
aji-66	107	3	editor(s	editor(s	PROPN
aji-66	107	4	):	):	PUNCT
aji-66	107	5	(	(	PUNCT
aji-66	107	6	1	1	X
aji-66	107	7	)	)	PUNCT
aji-66	107	8	dr	dr	PROPN
aji-66	107	9	.	.	PROPN
aji-66	107	10	cynthia	cynthia	PROPN
aji-66	107	11	aracely	aracely	ADV
aji-66	107	12	alvizo	alvizo	VERB
aji-66	107	13	báez	báez	ADJ
aji-66	107	14	,	,	PUNCT
aji-66	107	15	autonomous	autonomous	ADJ
aji-66	107	16	university	university	PROPN
aji-66	107	17	of	of	ADP
aji-66	107	18	nuevo	nuevo	PROPN
aji-66	107	19	leon	leon	PROPN
aji-66	107	20	,	,	PUNCT
aji-66	107	21	mexico	mexico	PROPN
aji-66	107	22	.	.	PUNCT
aji-66	108	1	reviewers	reviewer	NOUN
aji-66	108	2	:	:	PUNCT
aji-66	108	3	(	(	PUNCT
aji-66	108	4	1	1	X
aji-66	108	5	)	)	PUNCT
aji-66	108	6	g	g	PROPN
aji-66	108	7	-	-	PUNCT
aji-66	108	8	halli	halli	PROPN
aji-66	108	9	r.	r.	PROPN
aji-66	108	10	rajasekariah	rajasekariah	PROPN
aji-66	108	11	,	,	PUNCT
aji-66	108	12	biofirm	biofirm	PROPN
aji-66	108	13	pty	pty	PROPN
aji-66	108	14	ltd	ltd	PROPN
aji-66	108	15	,	,	PUNCT
aji-66	108	16	australia	australia	PROPN
aji-66	108	17	.	.	PUNCT
aji-66	109	1	(	(	PUNCT
aji-66	109	2	2	2	X
aji-66	109	3	)	)	PUNCT
aji-66	109	4	wagner	wagner	PROPN
aji-66	109	5	quintilio	quintilio	PROPN
aji-66	109	6	,	,	PUNCT
aji-66	109	7	instituto	instituto	PROPN
aji-66	109	8	butantan	butantan	PROPN
aji-66	109	9	,	,	PUNCT
aji-66	109	10	brazil	brazil	PROPN
aji-66	109	11	.	.	PUNCT
aji-66	110	1	complete	complete	ADJ
aji-66	110	2	peer	peer	NOUN
aji-66	110	3	review	review	NOUN
aji-66	110	4	history	history	NOUN
aji-66	110	5	:	:	PUNCT
aji-66	110	6	https://www.sdiarticle4.com/review-history/69854	https://www.sdiarticle4.com/review-history/69854	X
aji-66	110	7	received	receive	VERB
aji-66	110	8	15	15	NUM
aji-66	110	9	may	may	NOUN
aji-66	110	10	2021	2021	NUM
aji-66	110	11	accepted	accept	VERB
aji-66	110	12	19	19	NUM
aji-66	110	13	july	july	PROPN
aji-66	110	14	2021	2021	NUM
aji-66	110	15	published	publish	VERB
aji-66	110	16	03	03	NUM
aji-66	110	17	august	august	PROPN
aji-66	110	18	2021	2021	NUM
aji-66	110	19	abstract	abstract	ADJ
aji-66	110	20	malaria	malaria	NOUN
aji-66	110	21	continues	continue	VERB
aji-66	110	22	to	to	PART
aji-66	110	23	cause	cause	VERB
aji-66	110	24	enormous	enormous	ADJ
aji-66	110	25	human	human	ADJ
aji-66	110	26	suffering	suffering	NOUN
aji-66	110	27	throughout	throughout	ADP
aji-66	110	28	most	most	ADJ
aji-66	110	29	of	of	ADP
aji-66	110	30	the	the	DET
aji-66	110	31	tropics	tropic	NOUN
aji-66	110	32	and	and	CCONJ
aji-66	110	33	subtropics	subtropic	NOUN
aji-66	110	34	.	.	PUNCT
aji-66	111	1	in	in	ADP
aji-66	111	2	sub	sub	ADJ
aji-66	111	3	-	-	ADJ
aji-66	111	4	saharan	saharan	ADJ
aji-66	111	5	africa	africa	PROPN
aji-66	111	6	alone	alone	ADV
aji-66	111	7	,	,	PUNCT
aji-66	111	8	it	it	PRON
aji-66	111	9	is	be	AUX
aji-66	111	10	estimated	estimate	VERB
aji-66	111	11	that	that	SCONJ
aji-66	111	12	about	about	ADV
aji-66	111	13	two	two	NUM
aji-66	111	14	million	million	NUM
aji-66	111	15	children	child	NOUN
aji-66	111	16	die	die	VERB
aji-66	111	17	each	each	DET
aji-66	111	18	year	year	NOUN
aji-66	111	19	due	due	ADP
aji-66	111	20	to	to	ADP
aji-66	111	21	malaria	malaria	NOUN
aji-66	111	22	.	.	PUNCT
aji-66	112	1	vector	vector	NOUN
aji-66	112	2	control	control	NOUN
aji-66	112	3	and	and	CCONJ
aji-66	112	4	malaria	malaria	NOUN
aji-66	112	5	chemotherapy	chemotherapy	NOUN
aji-66	112	6	strategies	strategy	NOUN
aji-66	112	7	that	that	PRON
aji-66	112	8	were	be	AUX
aji-66	112	9	previously	previously	ADV
aji-66	112	10	effective	effective	ADJ
aji-66	112	11	in	in	ADP
aji-66	112	12	controlling	control	VERB
aji-66	112	13	and	and	CCONJ
aji-66	112	14	treating	treat	VERB
aji-66	112	15	malaria	malaria	NOUN
aji-66	112	16	,	,	PUNCT
aji-66	112	17	respectively	respectively	ADV
aji-66	112	18	,	,	PUNCT
aji-66	112	19	are	be	AUX
aji-66	112	20	now	now	ADV
aji-66	112	21	largely	largely	ADV
aji-66	112	22	ineffective	ineffective	ADJ
aji-66	112	23	owing	owe	VERB
aji-66	112	24	to	to	ADP
aji-66	112	25	the	the	DET
aji-66	112	26	spread	spread	NOUN
aji-66	112	27	of	of	ADP
aji-66	112	28	insecticide	insecticide	NOUN
aji-66	112	29	-	-	PUNCT
aji-66	112	30	resistant	resistant	ADJ
aji-66	112	31	mosquitoes	mosquito	NOUN
aji-66	112	32	and	and	CCONJ
aji-66	112	33	drug	drug	NOUN
aji-66	112	34	-	-	PUNCT
aji-66	112	35	resistant	resistant	ADJ
aji-66	112	36	parasites	parasite	NOUN
aji-66	112	37	.	.	PUNCT
aji-66	113	1	a	a	DET
aji-66	113	2	vaccine	vaccine	NOUN
aji-66	113	3	targeting	target	VERB
aji-66	113	4	the	the	DET
aji-66	113	5	sexual	sexual	ADJ
aji-66	113	6	stages	stage	NOUN
aji-66	113	7	of	of	ADP
aji-66	113	8	the	the	DET
aji-66	113	9	parasite	parasite	NOUN
aji-66	113	10	and	and	CCONJ
aji-66	113	11	block	block	NOUN
aji-66	113	12	transmission	transmission	NOUN
aji-66	113	13	is	be	AUX
aji-66	113	14	needed	need	VERB
aji-66	113	15	to	to	PART
aji-66	113	16	reinforce	reinforce	VERB
aji-66	113	17	current	current	ADJ
aji-66	113	18	malaria	malaria	NOUN
aji-66	113	19	control	control	NOUN
aji-66	113	20	and	and	CCONJ
aji-66	113	21	eradication	eradication	NOUN
aji-66	113	22	efforts	effort	NOUN
aji-66	113	23	.	.	PUNCT
aji-66	114	1	here	here	ADV
aji-66	114	2	,	,	PUNCT
aji-66	114	3	we	we	PRON
aji-66	114	4	review	review	VERB
aji-66	114	5	the	the	DET
aji-66	114	6	status	status	NOUN
aji-66	114	7	of	of	ADP
aji-66	114	8	malaria	malaria	NOUN
aji-66	114	9	transmission	transmission	NOUN
aji-66	114	10	-	-	PUNCT
aji-66	114	11	blocking	block	VERB
aji-66	114	12	vaccines	vaccine	NOUN
aji-66	114	13	.	.	PUNCT
aji-66	115	1	we	we	PRON
aji-66	115	2	focused	focus	VERB
aji-66	115	3	on	on	ADP
aji-66	115	4	the	the	DET
aji-66	115	5	efficacy	efficacy	NOUN
aji-66	115	6	,	,	PUNCT
aji-66	115	7	progress	progress	NOUN
aji-66	115	8	and	and	CCONJ
aji-66	115	9	development	development	NOUN
aji-66	115	10	challenges	challenge	NOUN
aji-66	115	11	of	of	ADP
aji-66	115	12	transmission	transmission	NOUN
aji-66	115	13	-	-	PUNCT
aji-66	115	14	blocking	block	VERB
aji-66	115	15	vaccines	vaccine	NOUN
aji-66	115	16	.	.	PUNCT
aji-66	116	1	pfs25	pfs25	NOUN
aji-66	116	2	and	and	CCONJ
aji-66	116	3	pfs48/45	pfs48/45	NOUN
aji-66	116	4	are	be	AUX
aji-66	116	5	essentially	essentially	ADV
aji-66	116	6	the	the	DET
aji-66	116	7	lead	lead	ADJ
aji-66	116	8	-	-	PUNCT
aji-66	116	9	candidates	candidate	NOUN
aji-66	116	10	malaria	malaria	NOUN
aji-66	116	11	transmission	transmission	NOUN
aji-66	116	12	-	-	PUNCT
aji-66	116	13	blocking	block	VERB
aji-66	116	14	vaccine	vaccine	NOUN
aji-66	116	15	and	and	CCONJ
aji-66	116	16	should	should	AUX
aji-66	116	17	be	be	AUX
aji-66	116	18	studied	study	VERB
aji-66	116	19	further	far	ADV
aji-66	116	20	in	in	ADP
aji-66	116	21	clinical	clinical	ADJ
aji-66	116	22	trials	trial	NOUN
aji-66	116	23	.	.	PUNCT
aji-66	117	1	our	our	PRON
aji-66	117	2	review	review	NOUN
aji-66	117	3	highlights	highlight	VERB
aji-66	117	4	the	the	DET
aji-66	117	5	need	need	NOUN
aji-66	117	6	to	to	PART
aji-66	117	7	develop	develop	VERB
aji-66	117	8	novel	novel	ADJ
aji-66	117	9	malaria	malaria	NOUN
aji-66	117	10	elimination	elimination	NOUN
aji-66	117	11	interventions	intervention	NOUN
aji-66	117	12	,	,	PUNCT
aji-66	117	13	particularly	particularly	ADV
aji-66	117	14	an	an	DET
aji-66	117	15	effective	effective	ADJ
aji-66	117	16	malaria	malaria	NOUN
aji-66	117	17	vaccine	vaccine	NOUN
aji-66	117	18	with	with	ADP
aji-66	117	19	transmission	transmission	NOUN
aji-66	117	20	-	-	PUNCT
aji-66	117	21	blocking	block	VERB
aji-66	117	22	activity	activity	NOUN
aji-66	117	23	.	.	PUNCT
aji-66	118	1	review	review	NOUN
aji-66	118	2	article	article	NOUN
aji-66	118	3	wangai	wangai	PROPN
aji-66	118	4	et	et	PROPN
aji-66	118	5	al	al	PROPN
aji-66	118	6	.	.	PROPN
aji-66	118	7	;	;	PUNCT
aji-66	118	8	aji	aji	PROPN
aji-66	118	9	,	,	PUNCT
aji-66	118	10	4(1	4(1	NOUN
aji-66	118	11	):	):	PUNCT
aji-66	118	12	77	77	NUM
aji-66	118	13	-	-	SYM
aji-66	118	14	84	84	NUM
aji-66	118	15	,	,	PUNCT
aji-66	118	16	2021	2021	NUM
aji-66	118	17	;	;	PUNCT
aji-66	118	18	article	article	NOUN
aji-66	118	19	no.aji.69854	no.aji.69854	NOUN
aji-66	118	20	78	78	NUM
aji-66	118	21	keywords	keyword	NOUN
aji-66	118	22	:	:	PUNCT
aji-66	118	23	malaria	malaria	NOUN
aji-66	118	24	mosquitoes	mosquitoe	VERB
aji-66	118	25	pfs25	pfs25	PROPN
aji-66	118	26	pfs48/45	pfs48/45	VERB
aji-66	118	27	vaccines	vaccine	NOUN
aji-66	118	28	;	;	PUNCT
aji-66	118	29	drug	drug	NOUN
aji-66	118	30	-	-	PUNCT
aji-66	118	31	resistant	resistant	ADJ
aji-66	118	32	parasites	parasite	NOUN
aji-66	118	33	plasmodium	plasmodium	NOUN
aji-66	118	34	.	.	PUNCT
aji-66	119	1	1	1	X
aji-66	119	2	.	.	X
aji-66	119	3	background	background	NOUN
aji-66	119	4	information	information	NOUN
aji-66	119	5	malaria	malaria	NOUN
aji-66	119	6	is	be	AUX
aji-66	119	7	caused	cause	VERB
aji-66	119	8	by	by	ADP
aji-66	119	9	unicellular	unicellular	ADJ
aji-66	119	10	plasmodium	plasmodium	NOUN
aji-66	119	11	protozoan	protozoan	NOUN
aji-66	119	12	parasites	parasite	NOUN
aji-66	119	13	that	that	PRON
aji-66	119	14	are	be	AUX
aji-66	119	15	injected	inject	VERB
aji-66	119	16	by	by	ADP
aji-66	119	17	female	female	ADJ
aji-66	119	18	anopheles	anophele	NOUN
aji-66	119	19	mosquitoes	mosquito	NOUN
aji-66	119	20	.	.	PUNCT
aji-66	120	1	p.	p.	NOUN
aji-66	120	2	falciparum	falciparum	NOUN
aji-66	120	3	,	,	PUNCT
aji-66	120	4	which	which	PRON
aji-66	120	5	causes	cause	VERB
aji-66	120	6	the	the	DET
aji-66	120	7	most	most	ADV
aji-66	120	8	severe	severe	ADJ
aji-66	120	9	form	form	NOUN
aji-66	120	10	of	of	ADP
aji-66	120	11	malaria	malaria	NOUN
aji-66	120	12	,	,	PUNCT
aji-66	120	13	is	be	AUX
aji-66	120	14	a	a	DET
aji-66	120	15	substantial	substantial	ADJ
aji-66	120	16	threat	threat	NOUN
aji-66	120	17	today	today	NOUN
aji-66	120	18	,	,	PUNCT
aji-66	120	19	causing	cause	VERB
aji-66	120	20	more	more	ADJ
aji-66	120	21	than	than	ADP
aji-66	120	22	200	200	NUM
aji-66	120	23	million	million	NUM
aji-66	120	24	clinical	clinical	ADJ
aji-66	120	25	cases	case	NOUN
aji-66	120	26	and	and	CCONJ
aji-66	120	27	409,000	409,000	NUM
aji-66	120	28	deaths	death	NOUN
aji-66	120	29	in	in	ADP
aji-66	120	30	2019	2019	NUM
aji-66	120	31	[	[	X
aji-66	120	32	1	1	NUM
aji-66	120	33	]	]	PUNCT
aji-66	120	34	.	.	PUNCT
aji-66	121	1	while	while	SCONJ
aji-66	121	2	the	the	DET
aji-66	121	3	level	level	NOUN
aji-66	121	4	of	of	ADP
aji-66	121	5	malaria	malaria	NOUN
aji-66	121	6	has	have	AUX
aji-66	121	7	dropped	drop	VERB
aji-66	121	8	over	over	ADP
aji-66	121	9	the	the	DET
aji-66	121	10	last	last	ADJ
aji-66	121	11	10	10	NUM
aji-66	121	12	years	year	NOUN
aji-66	121	13	,	,	PUNCT
aji-66	121	14	this	this	DET
aji-66	121	15	decline	decline	NOUN
aji-66	121	16	has	have	AUX
aji-66	121	17	recently	recently	ADV
aji-66	121	18	stalled	stall	VERB
aji-66	121	19	,	,	PUNCT
aji-66	121	20	with	with	ADP
aji-66	121	21	some	some	DET
aji-66	121	22	regions	region	NOUN
aji-66	121	23	experiencing	experience	VERB
aji-66	121	24	a	a	DET
aji-66	121	25	resurgence	resurgence	NOUN
aji-66	121	26	in	in	ADP
aji-66	121	27	the	the	DET
aji-66	121	28	number	number	NOUN
aji-66	121	29	of	of	ADP
aji-66	121	30	malaria	malaria	NOUN
aji-66	121	31	cases	case	NOUN
aji-66	121	32	[	[	X
aji-66	121	33	2	2	NUM
aji-66	121	34	]	]	PUNCT
aji-66	121	35	.	.	PUNCT
aji-66	122	1	unfortunately	unfortunately	ADV
aji-66	122	2	,	,	PUNCT
aji-66	122	3	resistance	resistance	NOUN
aji-66	122	4	to	to	ADP
aji-66	122	5	artemisinin	artemisinin	NOUN
aji-66	122	6	-	-	PUNCT
aji-66	122	7	based	base	VERB
aji-66	122	8	combination	combination	NOUN
aji-66	122	9	therapy	therapy	NOUN
aji-66	122	10	(	(	PUNCT
aji-66	122	11	act	act	PROPN
aji-66	122	12	)	)	PUNCT
aji-66	122	13	,	,	PUNCT
aji-66	122	14	the	the	DET
aji-66	122	15	current	current	ADJ
aji-66	122	16	frontline	frontline	NOUN
aji-66	122	17	treatment	treatment	NOUN
aji-66	122	18	for	for	ADP
aji-66	122	19	malaria	malaria	NOUN
aji-66	122	20	,	,	PUNCT
aji-66	122	21	is	be	AUX
aji-66	122	22	present	present	ADJ
aji-66	122	23	in	in	ADP
aji-66	122	24	southeast	southeast	PROPN
aji-66	122	25	asia	asia	PROPN
aji-66	122	26	and	and	CCONJ
aji-66	122	27	now	now	ADV
aji-66	122	28	spreading	spread	VERB
aji-66	122	29	in	in	ADP
aji-66	122	30	africa	africa	PROPN
aji-66	123	1	[	[	X
aji-66	123	2	3	3	NUM
aji-66	123	3	]	]	PUNCT
aji-66	123	4	.	.	PUNCT
aji-66	124	1	this	this	DET
aji-66	124	2	highlights	highlight	VERB
aji-66	124	3	the	the	DET
aji-66	124	4	need	need	NOUN
aji-66	124	5	for	for	ADP
aji-66	124	6	novel	novel	ADJ
aji-66	124	7	strategies	strategy	NOUN
aji-66	124	8	in	in	ADP
aji-66	124	9	malaria	malaria	NOUN
aji-66	124	10	prophylaxis	prophylaxis	NOUN
aji-66	124	11	and	and	CCONJ
aji-66	124	12	treatment	treatment	NOUN
aji-66	124	13	,	,	PUNCT
aji-66	124	14	especially	especially	ADV
aji-66	124	15	an	an	DET
aji-66	124	16	effective	effective	ADJ
aji-66	124	17	vaccine	vaccine	NOUN
aji-66	124	18	that	that	PRON
aji-66	124	19	can	can	AUX
aji-66	124	20	induce	induce	VERB
aji-66	124	21	a	a	DET
aji-66	124	22	protective	protective	ADJ
aji-66	124	23	antimalaria	antimalaria	NOUN
aji-66	124	24	immune	immune	ADJ
aji-66	124	25	response	response	NOUN
aji-66	124	26	.	.	PUNCT
aji-66	125	1	even	even	ADV
aji-66	125	2	though	though	SCONJ
aji-66	125	3	the	the	DET
aji-66	125	4	development	development	NOUN
aji-66	125	5	of	of	ADP
aji-66	125	6	a	a	DET
aji-66	125	7	malaria	malaria	NOUN
aji-66	125	8	vaccine	vaccine	NOUN
aji-66	125	9	is	be	AUX
aji-66	125	10	still	still	ADV
aji-66	125	11	a	a	DET
aji-66	125	12	challenging	challenging	ADJ
aji-66	125	13	task	task	NOUN
aji-66	125	14	,	,	PUNCT
aji-66	125	15	the	the	DET
aji-66	125	16	development	development	NOUN
aji-66	125	17	of	of	ADP
aji-66	125	18	several	several	ADJ
aji-66	125	19	vaccine	vaccine	NOUN
aji-66	125	20	candidates	candidate	NOUN
aji-66	125	21	is	be	AUX
aji-66	125	22	ongoing	ongoing	ADJ
aji-66	125	23	.	.	PUNCT
aji-66	126	1	malaria	malaria	NOUN
aji-66	126	2	vaccines	vaccine	NOUN
aji-66	126	3	can	can	AUX
aji-66	126	4	thus	thus	ADV
aji-66	126	5	be	be	AUX
aji-66	126	6	broadly	broadly	ADV
aji-66	126	7	categorised	categorise	VERB
aji-66	126	8	into	into	ADP
aji-66	126	9	three	three	NUM
aji-66	126	10	groups	group	NOUN
aji-66	126	11	based	base	VERB
aji-66	126	12	on	on	ADP
aji-66	126	13	the	the	DET
aji-66	126	14	parasite	parasite	NOUN
aji-66	126	15	stage	stage	NOUN
aji-66	126	16	being	be	AUX
aji-66	126	17	targeted	target	VERB
aji-66	126	18	,	,	PUNCT
aji-66	126	19	namely	namely	ADV
aji-66	126	20	sporozoite	sporozoite	ADJ
aji-66	126	21	,	,	PUNCT
aji-66	126	22	liver	liver	NOUN
aji-66	126	23	-	-	PUNCT
aji-66	126	24	stage	stage	NOUN
aji-66	126	25	and	and	CCONJ
aji-66	126	26	asexual	asexual	ADJ
aji-66	126	27	blood	blood	NOUN
aji-66	126	28	-	-	PUNCT
aji-66	126	29	stage	stage	NOUN
aji-66	126	30	vaccines	vaccine	NOUN
aji-66	126	31	.	.	PUNCT
aji-66	127	1	liver	liver	NOUN
aji-66	127	2	-	-	PUNCT
aji-66	127	3	stage	stage	NOUN
aji-66	127	4	and	and	CCONJ
aji-66	127	5	asexual	asexual	ADJ
aji-66	127	6	blood	blood	NOUN
aji-66	127	7	-	-	PUNCT
aji-66	127	8	stage	stage	NOUN
aji-66	127	9	malaria	malaria	NOUN
aji-66	127	10	vaccines	vaccine	NOUN
aji-66	127	11	(	(	PUNCT
aji-66	127	12	a	a	DET
aji-66	127	13	transmission	transmission	NOUN
aji-66	127	14	-	-	PUNCT
aji-66	127	15	blocking	block	VERB
aji-66	127	16	vaccine	vaccine	NOUN
aji-66	127	17	)	)	PUNCT
aji-66	127	18	,	,	PUNCT
aji-66	127	19	unlike	unlike	ADP
aji-66	127	20	an	an	DET
aji-66	127	21	anti	anti	ADJ
aji-66	127	22	-	-	ADJ
aji-66	127	23	sporozoite	sporozoite	ADJ
aji-66	127	24	vaccine	vaccine	NOUN
aji-66	127	25	,	,	PUNCT
aji-66	127	26	do	do	AUX
aji-66	127	27	not	not	PART
aji-66	127	28	either	either	ADV
aji-66	127	29	directly	directly	ADV
aji-66	127	30	protect	protect	VERB
aji-66	127	31	a	a	DET
aji-66	127	32	vaccinee	vaccinee	NOUN
aji-66	127	33	against	against	ADP
aji-66	127	34	malaria	malaria	NOUN
aji-66	127	35	infection	infection	NOUN
aji-66	127	36	,	,	PUNCT
aji-66	127	37	reduce	reduce	VERB
aji-66	127	38	parasitaemia	parasitaemia	NOUN
aji-66	127	39	or	or	CCONJ
aji-66	127	40	prevent	prevent	VERB
aji-66	127	41	disease	disease	NOUN
aji-66	127	42	;	;	PUNCT
aji-66	127	43	but	but	CCONJ
aji-66	127	44	rather	rather	ADV
aji-66	127	45	employs	employ	VERB
aji-66	127	46	all	all	DET
aji-66	127	47	these	these	DET
aji-66	127	48	four	four	NUM
aji-66	127	49	strategies	strategy	NOUN
aji-66	127	50	.	.	PUNCT
aji-66	128	1	anti	anti	ADJ
aji-66	128	2	-	-	ADJ
aji-66	128	3	sporozoite	sporozoite	ADJ
aji-66	128	4	vaccines	vaccine	NOUN
aji-66	128	5	would	would	AUX
aji-66	128	6	help	help	VERB
aji-66	128	7	by	by	ADP
aji-66	128	8	preventing	prevent	VERB
aji-66	128	9	malaria	malaria	NOUN
aji-66	128	10	-	-	PUNCT
aji-66	128	11	infected	infect	VERB
aji-66	128	12	travellers	traveller	NOUN
aji-66	128	13	from	from	ADP
aji-66	128	14	transferring	transfer	VERB
aji-66	128	15	malaria	malaria	NOUN
aji-66	128	16	parasite	parasite	NOUN
aji-66	128	17	into	into	ADP
aji-66	128	18	a	a	DET
aji-66	128	19	malaria	malaria	NOUN
aji-66	128	20	-	-	PUNCT
aji-66	128	21	free	free	ADJ
aji-66	128	22	zone	zone	NOUN
aji-66	128	23	[	[	X
aji-66	128	24	4	4	NUM
aji-66	128	25	]	]	PUNCT
aji-66	128	26	.	.	PUNCT
aji-66	129	1	the	the	DET
aji-66	129	2	malaria	malaria	NOUN
aji-66	129	3	parasite	parasite	NOUN
aji-66	129	4	is	be	AUX
aji-66	129	5	particularly	particularly	ADV
aji-66	129	6	vulnerable	vulnerable	ADJ
aji-66	129	7	to	to	ADP
aji-66	129	8	immune	immune	ADJ
aji-66	129	9	intervention	intervention	NOUN
aji-66	129	10	during	during	ADP
aji-66	129	11	the	the	DET
aji-66	129	12	sexual	sexual	ADJ
aji-66	129	13	and	and	CCONJ
aji-66	129	14	sporogony	sporogony	ADJ
aji-66	129	15	stages	stage	NOUN
aji-66	129	16	because	because	SCONJ
aji-66	129	17	(	(	PUNCT
aji-66	129	18	1	1	X
aji-66	129	19	)	)	PUNCT
aji-66	129	20	parasites	parasite	NOUN
aji-66	129	21	pass	pass	VERB
aji-66	129	22	through	through	ADP
aji-66	129	23	a	a	DET
aji-66	129	24	substantial	substantial	ADJ
aji-66	129	25	numerical	numerical	ADJ
aji-66	129	26	bottleneck	bottleneck	NOUN
aji-66	129	27	-	-	PUNCT
aji-66	129	28	with	with	ADP
aji-66	129	29	about	about	ADV
aji-66	129	30	100	100	NUM
aji-66	129	31	parasites	parasite	NOUN
aji-66	129	32	of	of	ADP
aji-66	129	33	the	the	DET
aji-66	129	34	billions	billion	NOUN
aji-66	129	35	of	of	ADP
aji-66	129	36	asexual	asexual	ADJ
aji-66	129	37	blood	blood	NOUN
aji-66	129	38	-	-	PUNCT
aji-66	129	39	stage	stage	NOUN
aji-66	129	40	parasites	parasite	NOUN
aji-66	129	41	developing	develop	VERB
aji-66	129	42	into	into	ADP
aji-66	129	43	gametocytes	gametocyte	NOUN
aji-66	129	44	,	,	PUNCT
aji-66	129	45	get	get	AUX
aji-66	129	46	ingested	ingest	VERB
aji-66	129	47	by	by	ADP
aji-66	129	48	mosquitoes	mosquito	NOUN
aji-66	129	49	and	and	CCONJ
aji-66	129	50	subsequently	subsequently	ADV
aji-66	129	51	developing	develop	VERB
aji-66	129	52	into	into	ADP
aji-66	129	53	oocysts	oocyst	NOUN
aji-66	129	54	;	;	PUNCT
aji-66	129	55	(	(	PUNCT
aji-66	129	56	2	2	X
aji-66	129	57	)	)	PUNCT
aji-66	129	58	the	the	DET
aji-66	129	59	sexual	sexual	ADJ
aji-66	129	60	and	and	CCONJ
aji-66	129	61	sporogony	sporogony	ADJ
aji-66	129	62	stages	stage	NOUN
aji-66	129	63	persist	persist	VERB
aji-66	129	64	extracellularly	extracellularly	ADV
aji-66	129	65	for	for	ADP
aji-66	129	66	hours	hour	NOUN
aji-66	129	67	unlike	unlike	ADP
aji-66	129	68	other	other	ADJ
aji-66	129	69	parasite	parasite	NOUN
aji-66	129	70	stages	stage	NOUN
aji-66	129	71	;	;	PUNCT
aji-66	129	72	(	(	PUNCT
aji-66	129	73	3	3	X
aji-66	129	74	)	)	PUNCT
aji-66	129	75	many	many	ADJ
aji-66	129	76	of	of	ADP
aji-66	129	77	the	the	DET
aji-66	129	78	candidate	candidate	NOUN
aji-66	129	79	antigens	antigen	NOUN
aji-66	129	80	tend	tend	VERB
aji-66	129	81	to	to	PART
aji-66	129	82	be	be	AUX
aji-66	129	83	highly	highly	ADV
aji-66	129	84	immunogenic	immunogenic	ADJ
aji-66	129	85	owing	owe	VERB
aji-66	129	86	to	to	ADP
aji-66	129	87	their	their	PRON
aji-66	129	88	low	low	ADJ
aji-66	129	89	antigenic	antigenic	ADJ
aji-66	129	90	diversity	diversity	NOUN
aji-66	129	91	as	as	ADP
aji-66	129	92	a	a	DET
aji-66	129	93	result	result	NOUN
aji-66	129	94	of	of	ADP
aji-66	129	95	no	no	DET
aji-66	129	96	immune	immune	ADJ
aji-66	129	97	selection	selection	NOUN
aji-66	129	98	in	in	ADP
aji-66	129	99	host	host	NOUN
aji-66	129	100	since	since	SCONJ
aji-66	129	101	parasites	parasite	NOUN
aji-66	129	102	do	do	AUX
aji-66	129	103	not	not	PART
aji-66	129	104	express	express	VERB
aji-66	129	105	vaccine	vaccine	NOUN
aji-66	129	106	candidate	candidate	NOUN
aji-66	129	107	antigens	antigen	NOUN
aji-66	129	108	while	while	SCONJ
aji-66	129	109	in	in	ADP
aji-66	129	110	the	the	DET
aji-66	129	111	human	human	ADJ
aji-66	129	112	host	host	NOUN
aji-66	129	113	[	[	X
aji-66	129	114	5	5	NUM
aji-66	129	115	]	]	PUNCT
aji-66	129	116	.	.	PUNCT
aji-66	130	1	although	although	SCONJ
aji-66	130	2	antibodies	antibody	NOUN
aji-66	130	3	targeting	target	VERB
aji-66	130	4	gametocytes	gametocyte	NOUN
aji-66	130	5	(	(	PUNCT
aji-66	130	6	sexual	sexual	ADJ
aji-66	130	7	stages	stage	NOUN
aji-66	130	8	)	)	PUNCT
aji-66	130	9	are	be	AUX
aji-66	130	10	not	not	PART
aji-66	130	11	able	able	ADJ
aji-66	130	12	to	to	PART
aji-66	130	13	block	block	VERB
aji-66	130	14	human	human	ADJ
aji-66	130	15	infection	infection	NOUN
aji-66	130	16	or	or	CCONJ
aji-66	130	17	disease	disease	NOUN
aji-66	130	18	,	,	PUNCT
aji-66	130	19	they	they	PRON
aji-66	130	20	can	can	AUX
aji-66	130	21	potentially	potentially	ADV
aji-66	130	22	stop	stop	VERB
aji-66	130	23	malaria	malaria	NOUN
aji-66	130	24	transmission	transmission	NOUN
aji-66	130	25	.	.	PUNCT
aji-66	131	1	recently	recently	ADV
aji-66	131	2	,	,	PUNCT
aji-66	131	3	there	there	PRON
aji-66	131	4	has	have	AUX
aji-66	131	5	been	be	AUX
aji-66	131	6	increasing	increase	VERB
aji-66	131	7	interest	interest	NOUN
aji-66	131	8	in	in	ADP
aji-66	131	9	the	the	DET
aji-66	131	10	use	use	NOUN
aji-66	131	11	of	of	ADP
aji-66	131	12	gametocytespecific	gametocytespecific	ADJ
aji-66	131	13	antigens	antigen	NOUN
aji-66	131	14	as	as	ADP
aji-66	131	15	candidates	candidate	NOUN
aji-66	131	16	for	for	ADP
aji-66	131	17	a	a	DET
aji-66	131	18	transmission	transmission	NOUN
aji-66	131	19	-	-	PUNCT
aji-66	131	20	blocking	block	VERB
aji-66	131	21	vaccine	vaccine	NOUN
aji-66	131	22	(	(	PUNCT
aji-66	131	23	tbv	tbv	NOUN
aji-66	131	24	)	)	PUNCT
aji-66	132	1	[	[	X
aji-66	132	2	6	6	NUM
aji-66	132	3	]	]	PUNCT
aji-66	132	4	.	.	PUNCT
aji-66	133	1	such	such	DET
aji-66	133	2	a	a	DET
aji-66	133	3	vaccine	vaccine	NOUN
aji-66	133	4	would	would	AUX
aji-66	133	5	induce	induce	VERB
aji-66	133	6	antibody	antibody	NOUN
aji-66	133	7	production	production	NOUN
aji-66	133	8	that	that	PRON
aji-66	133	9	is	be	AUX
aji-66	133	10	taken	take	VERB
aji-66	133	11	up	up	ADP
aji-66	133	12	alongside	alongside	ADP
aji-66	133	13	the	the	DET
aji-66	133	14	gametocytes	gametocyte	NOUN
aji-66	133	15	during	during	ADP
aji-66	133	16	a	a	DET
aji-66	133	17	mosquito	mosquito	ADJ
aji-66	133	18	blood	blood	NOUN
aji-66	133	19	meal	meal	NOUN
aji-66	133	20	and	and	CCONJ
aji-66	133	21	neutralize	neutralize	VERB
aji-66	133	22	the	the	DET
aji-66	133	23	parasites	parasite	NOUN
aji-66	133	24	in	in	ADP
aji-66	133	25	the	the	DET
aji-66	133	26	mosquito	mosquito	ADJ
aji-66	133	27	midgut	midgut	NOUN
aji-66	133	28	upon	upon	SCONJ
aji-66	133	29	expression	expression	NOUN
aji-66	133	30	of	of	ADP
aji-66	133	31	the	the	DET
aji-66	133	32	antigens	antigen	NOUN
aji-66	133	33	.	.	PUNCT
aji-66	134	1	key	key	ADJ
aji-66	134	2	sexual	sexual	ADJ
aji-66	134	3	-	-	PUNCT
aji-66	134	4	stage	stage	NOUN
aji-66	134	5	antigens	antigen	NOUN
aji-66	134	6	that	that	PRON
aji-66	134	7	have	have	AUX
aji-66	134	8	been	be	AUX
aji-66	134	9	considered	consider	VERB
aji-66	134	10	as	as	SCONJ
aji-66	134	11	candidate	candidate	NOUN
aji-66	134	12	tbv	tbv	NOUN
aji-66	134	13	include	include	VERB
aji-66	134	14	pfs48/45	pfs48/45	NOUN
aji-66	134	15	,	,	PUNCT
aji-66	134	16	pfs230	pfs230	PROPN
aji-66	134	17	,	,	PUNCT
aji-66	134	18	pfs25	pfs25	NOUN
aji-66	134	19	,	,	PUNCT
aji-66	134	20	and	and	CCONJ
aji-66	134	21	pfs47	pfs47	PROPN
aji-66	134	22	[	[	X
aji-66	134	23	7,8	7,8	NUM
aji-66	134	24	]	]	PUNCT
aji-66	134	25	.	.	PUNCT
aji-66	135	1	it	it	PRON
aji-66	135	2	has	have	AUX
aji-66	135	3	been	be	AUX
aji-66	135	4	reported	report	VERB
aji-66	135	5	that	that	SCONJ
aji-66	135	6	antibodies	antibodie	VERB
aji-66	135	7	from	from	ADP
aji-66	135	8	malariaexposed	malariaexpose	VERB
aji-66	135	9	individuals	individual	NOUN
aji-66	135	10	or	or	CCONJ
aji-66	135	11	vaccinated	vaccinated	ADJ
aji-66	135	12	animals	animal	NOUN
aji-66	135	13	against	against	ADP
aji-66	135	14	these	these	DET
aji-66	135	15	antigens	antigen	NOUN
aji-66	135	16	could	could	AUX
aji-66	135	17	block	block	VERB
aji-66	135	18	malaria	malaria	NOUN
aji-66	135	19	parasite	parasite	NOUN
aji-66	135	20	development	development	NOUN
aji-66	135	21	in	in	ADP
aji-66	135	22	mosquitoes	mosquito	NOUN
aji-66	135	23	[	[	X
aji-66	135	24	9	9	NUM
aji-66	135	25	]	]	PUNCT
aji-66	135	26	.	.	PUNCT
aji-66	136	1	these	these	DET
aji-66	136	2	findings	finding	NOUN
aji-66	136	3	offer	offer	VERB
aji-66	136	4	an	an	DET
aji-66	136	5	impetus	impetus	NOUN
aji-66	136	6	to	to	PART
aji-66	136	7	test	test	VERB
aji-66	136	8	human	human	ADJ
aji-66	136	9	monoclonal	monoclonal	NOUN
aji-66	136	10	antibodies	antibody	NOUN
aji-66	136	11	against	against	ADP
aji-66	136	12	tbv	tbv	DET
aji-66	136	13	antigens	antigen	NOUN
aji-66	136	14	,	,	PUNCT
aji-66	136	15	such	such	ADJ
aji-66	136	16	as	as	ADP
aji-66	136	17	those	those	PRON
aji-66	136	18	generated	generate	VERB
aji-66	136	19	recently	recently	ADV
aji-66	136	20	against	against	ADP
aji-66	136	21	pfs25	pfs25	PROPN
aji-66	136	22	,	,	PUNCT
aji-66	136	23	for	for	ADP
aji-66	136	24	the	the	DET
aji-66	136	25	ability	ability	NOUN
aji-66	136	26	to	to	PART
aji-66	136	27	block	block	VERB
aji-66	136	28	malaria	malaria	NOUN
aji-66	136	29	transmission	transmission	NOUN
aji-66	136	30	.	.	PUNCT
aji-66	137	1	2	2	X
aji-66	137	2	.	.	X
aji-66	137	3	role	role	NOUN
aji-66	137	4	of	of	ADP
aji-66	137	5	transmission	transmission	NOUN
aji-66	137	6	-	-	PUNCT
aji-66	137	7	blocking	block	VERB
aji-66	137	8	vaccine	vaccine	NOUN
aji-66	137	9	the	the	DET
aji-66	137	10	main	main	ADJ
aji-66	137	11	goal	goal	NOUN
aji-66	137	12	of	of	ADP
aji-66	137	13	transmission	transmission	NOUN
aji-66	137	14	-	-	PUNCT
aji-66	137	15	blocking	block	VERB
aji-66	137	16	vaccine	vaccine	NOUN
aji-66	137	17	development	development	NOUN
aji-66	137	18	programs	program	NOUN
aji-66	137	19	is	be	AUX
aji-66	137	20	to	to	PART
aji-66	137	21	eradicate	eradicate	VERB
aji-66	137	22	malaria	malaria	NOUN
aji-66	137	23	parasites	parasite	NOUN
aji-66	137	24	using	use	VERB
aji-66	137	25	an	an	DET
aji-66	137	26	inexpensively	inexpensively	ADV
aji-66	137	27	produced	produce	VERB
aji-66	137	28	,	,	PUNCT
aji-66	137	29	stably	stably	ADV
aji-66	137	30	formulated	formulate	VERB
aji-66	137	31	,	,	PUNCT
aji-66	137	32	and	and	CCONJ
aji-66	137	33	easily	easily	ADV
aji-66	137	34	administered	administer	VERB
aji-66	137	35	vaccine	vaccine	NOUN
aji-66	137	36	.	.	PUNCT
aji-66	138	1	it	it	PRON
aji-66	138	2	is	be	AUX
aji-66	138	3	unlikely	unlikely	ADJ
aji-66	138	4	that	that	SCONJ
aji-66	138	5	a	a	DET
aji-66	138	6	single	single	ADJ
aji-66	138	7	antigen	antigen	ADJ
aji-66	138	8	subunit	subunit	NOUN
aji-66	138	9	vaccine	vaccine	NOUN
aji-66	138	10	will	will	AUX
aji-66	138	11	be	be	AUX
aji-66	138	12	enough	enough	ADJ
aji-66	138	13	.	.	PUNCT
aji-66	139	1	it	it	PRON
aji-66	139	2	noteworthy	noteworthy	ADJ
aji-66	139	3	however	however	ADV
aji-66	139	4	that	that	SCONJ
aji-66	139	5	transmission	transmission	NOUN
aji-66	139	6	-	-	PUNCT
aji-66	139	7	blocking	block	VERB
aji-66	139	8	vaccines	vaccine	NOUN
aji-66	139	9	will	will	AUX
aji-66	139	10	have	have	VERB
aji-66	139	11	a	a	DET
aji-66	139	12	great	great	ADJ
aji-66	139	13	impact	impact	NOUN
aji-66	139	14	on	on	ADP
aji-66	139	15	malaria	malaria	NOUN
aji-66	139	16	control	control	NOUN
aji-66	139	17	when	when	SCONJ
aji-66	139	18	they	they	PRON
aji-66	139	19	are	be	AUX
aji-66	139	20	combined	combine	VERB
aji-66	139	21	with	with	ADP
aji-66	139	22	other	other	ADJ
aji-66	139	23	vaccines	vaccine	NOUN
aji-66	139	24	or	or	CCONJ
aji-66	139	25	control	control	NOUN
aji-66	139	26	modalities	modality	NOUN
aji-66	139	27	.	.	PUNCT
aji-66	140	1	these	these	PRON
aji-66	140	2	may	may	AUX
aji-66	140	3	include	include	VERB
aji-66	140	4	bed	bed	NOUN
aji-66	140	5	nets	net	NOUN
aji-66	140	6	,	,	PUNCT
aji-66	140	7	protective	protective	ADJ
aji-66	140	8	vaccines	vaccine	NOUN
aji-66	140	9	,	,	PUNCT
aji-66	140	10	and	and	CCONJ
aji-66	140	11	massive	massive	ADJ
aji-66	140	12	chemotherapy	chemotherapy	NOUN
aji-66	140	13	administration	administration	NOUN
aji-66	140	14	,	,	PUNCT
aji-66	140	15	in	in	ADP
aji-66	140	16	controlling	control	VERB
aji-66	140	17	or	or	CCONJ
aji-66	140	18	even	even	ADV
aji-66	140	19	perhaps	perhaps	ADV
aji-66	140	20	eradicating	eradicate	VERB
aji-66	140	21	malaria	malaria	NOUN
aji-66	140	22	in	in	ADP
aji-66	140	23	geographically	geographically	ADV
aji-66	140	24	isolated	isolate	VERB
aji-66	140	25	areas	area	NOUN
aji-66	140	26	e.g.	e.g.	ADV
aji-66	140	27	islands	island	NOUN
aji-66	140	28	or	or	CCONJ
aji-66	140	29	isolated	isolate	VERB
aji-66	140	30	human	human	ADJ
aji-66	140	31	and	and	CCONJ
aji-66	140	32	mosquito	mosquito	ADJ
aji-66	140	33	populations	population	NOUN
aji-66	140	34	)	)	PUNCT
aji-66	141	1	[	[	X
aji-66	141	2	10	10	NUM
aji-66	141	3	]	]	PUNCT
aji-66	141	4	.	.	PUNCT
aji-66	142	1	in	in	ADP
aji-66	142	2	instances	instance	NOUN
aji-66	142	3	where	where	SCONJ
aji-66	142	4	malaria	malaria	NOUN
aji-66	142	5	is	be	AUX
aji-66	142	6	eradicated	eradicate	VERB
aji-66	142	7	,	,	PUNCT
aji-66	142	8	long	long	ADJ
aji-66	142	9	-	-	PUNCT
aji-66	142	10	term	term	NOUN
aji-66	142	11	control	control	NOUN
aji-66	142	12	will	will	AUX
aji-66	142	13	be	be	AUX
aji-66	142	14	necessary	necessary	ADJ
aji-66	142	15	to	to	PART
aji-66	142	16	prevent	prevent	VERB
aji-66	142	17	the	the	DET
aji-66	142	18	re	re	NOUN
aji-66	142	19	-	-	NOUN
aji-66	142	20	introduction	introduction	NOUN
aji-66	142	21	of	of	ADP
aji-66	142	22	the	the	DET
aji-66	142	23	parasite	parasite	NOUN
aji-66	142	24	.	.	PUNCT
aji-66	143	1	this	this	PRON
aji-66	143	2	could	could	AUX
aji-66	143	3	be	be	AUX
aji-66	143	4	accomplished	accomplish	VERB
aji-66	143	5	by	by	ADP
aji-66	143	6	enforcement	enforcement	NOUN
aji-66	143	7	of	of	ADP
aji-66	143	8	mandatory	mandatory	ADJ
aji-66	143	9	tbv	tbv	PRON
aji-66	143	10	vaccination	vaccination	NOUN
aji-66	143	11	for	for	ADP
aji-66	143	12	persons	person	NOUN
aji-66	143	13	returning	return	VERB
aji-66	143	14	from	from	ADP
aji-66	143	15	areas	area	NOUN
aji-66	143	16	where	where	SCONJ
aji-66	143	17	malaria	malaria	NOUN
aji-66	143	18	persists	persist	VERB
aji-66	143	19	and/or	and/or	CCONJ
aji-66	143	20	demonstrate	demonstrate	VERB
aji-66	143	21	evidence	evidence	NOUN
aji-66	143	22	of	of	ADP
aji-66	143	23	prior	prior	ADJ
aji-66	143	24	vaccination	vaccination	NOUN
aji-66	143	25	with	with	ADP
aji-66	143	26	tbv	tbv	PROPN
aji-66	143	27	.	.	PUNCT
aji-66	144	1	the	the	DET
aji-66	144	2	adoption	adoption	NOUN
aji-66	144	3	of	of	ADP
aji-66	144	4	tbv	tbv	PROPN
aji-66	144	5	combined	combine	VERB
aji-66	144	6	with	with	ADP
aji-66	144	7	other	other	ADJ
aji-66	144	8	malaria	malaria	NOUN
aji-66	144	9	control	control	NOUN
aji-66	144	10	strategies	strategy	NOUN
aji-66	144	11	may	may	AUX
aji-66	144	12	boost	boost	VERB
aji-66	144	13	the	the	DET
aji-66	144	14	effectiveness	effectiveness	NOUN
aji-66	144	15	of	of	ADP
aji-66	144	16	existing	exist	VERB
aji-66	144	17	malaria	malaria	NOUN
aji-66	144	18	control	control	NOUN
aji-66	144	19	efforts	effort	NOUN
aji-66	144	20	.	.	PUNCT
aji-66	145	1	firstly	firstly	ADV
aji-66	145	2	,	,	PUNCT
aji-66	145	3	a	a	DET
aji-66	145	4	combination	combination	NOUN
aji-66	145	5	of	of	ADP
aji-66	145	6	tbv	tbv	PRON
aji-66	145	7	and	and	CCONJ
aji-66	145	8	multistage	multistage	NOUN
aji-66	145	9	malaria	malaria	NOUN
aji-66	145	10	vaccines	vaccine	NOUN
aji-66	145	11	could	could	AUX
aji-66	145	12	contribute	contribute	VERB
aji-66	145	13	substantially	substantially	ADV
aji-66	145	14	in	in	ADP
aji-66	145	15	curtailing	curtail	VERB
aji-66	145	16	the	the	DET
aji-66	145	17	spread	spread	NOUN
aji-66	145	18	of	of	ADP
aji-66	145	19	’	'	PUNCT
aji-66	145	20	mutant	mutant	ADJ
aji-66	145	21	parasites	parasite	NOUN
aji-66	145	22	that	that	PRON
aji-66	145	23	may	may	AUX
aji-66	145	24	be	be	AUX
aji-66	145	25	resistant	resistant	ADJ
aji-66	145	26	against	against	ADP
aji-66	145	27	the	the	DET
aji-66	145	28	protective	protective	ADJ
aji-66	145	29	components	component	NOUN
aji-66	145	30	of	of	ADP
aji-66	145	31	the	the	DET
aji-66	145	32	vaccines	vaccine	NOUN
aji-66	145	33	by	by	ADP
aji-66	145	34	reducing	reduce	VERB
aji-66	145	35	malaria	malaria	NOUN
aji-66	145	36	wangai	wangai	NOUN
aji-66	145	37	et	et	PROPN
aji-66	145	38	al	al	PROPN
aji-66	145	39	.	.	PROPN
aji-66	145	40	;	;	PUNCT
aji-66	145	41	aji	aji	PROPN
aji-66	145	42	,	,	PUNCT
aji-66	145	43	4(1	4(1	NOUN
aji-66	145	44	):	):	PUNCT
aji-66	145	45	77	77	NUM
aji-66	145	46	-	-	SYM
aji-66	145	47	84	84	NUM
aji-66	145	48	,	,	PUNCT
aji-66	145	49	2021	2021	NUM
aji-66	145	50	;	;	PUNCT
aji-66	145	51	article	article	NOUN
aji-66	145	52	no.aji.69854	no.aji.69854	NOUN
aji-66	145	53	79	79	NUM
aji-66	145	54	transmission	transmission	NOUN
aji-66	145	55	to	to	ADP
aji-66	145	56	a	a	DET
aji-66	145	57	rate	rate	NOUN
aji-66	145	58	that	that	PRON
aji-66	145	59	would	would	AUX
aji-66	145	60	make	make	VERB
aji-66	145	61	an	an	DET
aji-66	145	62	otherwise	otherwise	ADV
aji-66	145	63	partially	partially	ADV
aji-66	145	64	effective	effective	ADJ
aji-66	145	65	protective	protective	ADJ
aji-66	145	66	component	component	NOUN
aji-66	145	67	highly	highly	ADV
aji-66	145	68	effective	effective	ADJ
aji-66	145	69	[	[	X
aji-66	145	70	11	11	NUM
aji-66	145	71	]	]	PUNCT
aji-66	145	72	.	.	PUNCT
aji-66	146	1	secondly	secondly	ADV
aji-66	146	2	,	,	PUNCT
aji-66	146	3	co	co	NOUN
aji-66	146	4	-	-	NOUN
aji-66	146	5	administration	administration	NOUN
aji-66	146	6	of	of	ADP
aji-66	146	7	tbv	tbv	PROPN
aji-66	146	8	with	with	ADP
aji-66	146	9	effective	effective	ADJ
aji-66	146	10	anti	anti	ADJ
aji-66	146	11	-	-	ADJ
aji-66	146	12	malarial	malarial	ADJ
aji-66	146	13	drugs	drug	NOUN
aji-66	146	14	will	will	AUX
aji-66	146	15	help	help	VERB
aji-66	146	16	prolong	prolong	VERB
aji-66	146	17	malaria	malaria	NOUN
aji-66	146	18	drug	drug	NOUN
aji-66	146	19	efficacy	efficacy	NOUN
aji-66	146	20	and	and	CCONJ
aji-66	146	21	delay	delay	VERB
aji-66	146	22	the	the	DET
aji-66	146	23	emergence	emergence	NOUN
aji-66	146	24	or	or	CCONJ
aji-66	146	25	spread	spread	VERB
aji-66	146	26	of	of	ADP
aji-66	146	27	drug	drug	NOUN
aji-66	146	28	-	-	PUNCT
aji-66	146	29	resistant	resistant	ADJ
aji-66	146	30	parasites	parasite	NOUN
aji-66	146	31	.	.	PUNCT
aji-66	147	1	finally	finally	ADV
aji-66	147	2	,	,	PUNCT
aji-66	147	3	tbv	tbv	PRON
aji-66	147	4	could	could	AUX
aji-66	147	5	reduce	reduce	VERB
aji-66	147	6	morbidity	morbidity	NOUN
aji-66	147	7	/	/	SYM
aji-66	147	8	mortality	mortality	NOUN
aji-66	147	9	caused	cause	VERB
aji-66	147	10	by	by	ADP
aji-66	147	11	the	the	DET
aji-66	147	12	spread	spread	NOUN
aji-66	147	13	of	of	ADP
aji-66	147	14	the	the	DET
aji-66	147	15	virulent	virulent	NOUN
aji-66	147	16	strains	strain	NOUN
aji-66	147	17	of	of	ADP
aji-66	147	18	the	the	DET
aji-66	147	19	parasite	parasite	NOUN
aji-66	147	20	.	.	PUNCT
aji-66	148	1	previous	previous	ADJ
aji-66	148	2	studies	study	NOUN
aji-66	148	3	have	have	AUX
aji-66	148	4	demonstrated	demonstrate	VERB
aji-66	148	5	that	that	SCONJ
aji-66	148	6	the	the	PRON
aji-66	148	7	more	more	ADV
aji-66	148	8	an	an	DET
aji-66	148	9	individual	individual	NOUN
aji-66	148	10	is	be	AUX
aji-66	148	11	exposed	expose	VERB
aji-66	148	12	to	to	ADP
aji-66	148	13	new	new	ADJ
aji-66	148	14	strains	strain	NOUN
aji-66	148	15	of	of	ADP
aji-66	148	16	parasites	parasite	NOUN
aji-66	148	17	,	,	PUNCT
aji-66	148	18	the	the	PRON
aji-66	148	19	more	more	ADV
aji-66	148	20	likely	likely	ADJ
aji-66	148	21	they	they	PRON
aji-66	148	22	are	be	AUX
aji-66	148	23	to	to	PART
aji-66	148	24	develop	develop	VERB
aji-66	148	25	severe	severe	ADJ
aji-66	148	26	clinical	clinical	ADJ
aji-66	148	27	disease	disease	NOUN
aji-66	148	28	[	[	X
aji-66	148	29	12–14	12–14	NUM
aji-66	148	30	]	]	X
aji-66	148	31	.	.	PUNCT
aji-66	149	1	however	however	ADV
aji-66	149	2	,	,	PUNCT
aji-66	149	3	it	it	PRON
aji-66	149	4	is	be	AUX
aji-66	149	5	still	still	ADV
aji-66	149	6	unclear	unclear	ADJ
aji-66	149	7	whether	whether	SCONJ
aji-66	149	8	this	this	DET
aji-66	149	9	phenomenon	phenomenon	NOUN
aji-66	149	10	is	be	AUX
aji-66	149	11	caused	cause	VERB
aji-66	149	12	by	by	ADP
aji-66	149	13	a	a	DET
aji-66	149	14	new	new	ADJ
aji-66	149	15	“	"	PUNCT
aji-66	149	16	virulent	virulent	NOUN
aji-66	149	17	”	"	PUNCT
aji-66	149	18	parasite	parasite	NOUN
aji-66	149	19	strain	strain	NOUN
aji-66	149	20	that	that	PRON
aji-66	149	21	is	be	AUX
aji-66	149	22	biologically	biologically	ADV
aji-66	149	23	different	different	ADJ
aji-66	149	24	(	(	PUNCT
aji-66	149	25	e.g.	e.g.	ADV
aji-66	149	26	,	,	PUNCT
aji-66	149	27	has	have	VERB
aji-66	149	28	a	a	DET
aji-66	149	29	different	different	ADJ
aji-66	149	30	cytoadherence	cytoadherence	NOUN
aji-66	149	31	profile	profile	NOUN
aji-66	149	32	)	)	PUNCT
aji-66	149	33	from	from	ADP
aji-66	149	34	other	other	ADJ
aji-66	149	35	strains	strain	NOUN
aji-66	149	36	circulating	circulate	VERB
aji-66	149	37	in	in	ADP
aji-66	149	38	a	a	DET
aji-66	149	39	geographical	geographical	ADJ
aji-66	149	40	area	area	NOUN
aji-66	149	41	[	[	X
aji-66	149	42	13	13	NUM
aji-66	149	43	]	]	PUNCT
aji-66	149	44	or	or	CCONJ
aji-66	149	45	it	it	PRON
aji-66	149	46	is	be	AUX
aji-66	149	47	simply	simply	ADV
aji-66	149	48	caused	cause	VERB
aji-66	149	49	by	by	ADP
aji-66	149	50	an	an	DET
aji-66	149	51	immunologically	immunologically	ADV
aji-66	149	52	new	new	ADJ
aji-66	149	53	strain	strain	NOUN
aji-66	149	54	to	to	ADP
aji-66	149	55	the	the	DET
aji-66	149	56	host	host	NOUN
aji-66	149	57	.	.	PUNCT
aji-66	150	1	3	3	X
aji-66	150	2	.	.	X
aji-66	150	3	candidate	candidate	NOUN
aji-66	150	4	vaccines	vaccine	NOUN
aji-66	150	5	prior	prior	ADJ
aji-66	150	6	fertilization	fertilization	NOUN
aji-66	150	7	,	,	PUNCT
aji-66	150	8	extracellular	extracellular	ADJ
aji-66	150	9	gamete	gamete	NOUN
aji-66	150	10	(	(	PUNCT
aji-66	150	11	male	male	ADJ
aji-66	150	12	and	and	CCONJ
aji-66	150	13	female)-specific	female)-specific	NOUN
aji-66	150	14	antigens	antigen	NOUN
aji-66	150	15	are	be	AUX
aji-66	150	16	the	the	DET
aji-66	150	17	earliest	early	ADJ
aji-66	150	18	point	point	NOUN
aji-66	150	19	during	during	ADP
aji-66	150	20	sexual	sexual	ADJ
aji-66	150	21	development	development	NOUN
aji-66	150	22	to	to	PART
aji-66	150	23	which	which	PRON
aji-66	150	24	an	an	DET
aji-66	150	25	antibodymediated	antibodymediate	VERB
aji-66	150	26	transmission	transmission	NOUN
aji-66	150	27	-	-	PUNCT
aji-66	150	28	blocking	block	VERB
aji-66	150	29	effect	effect	NOUN
aji-66	150	30	has	have	AUX
aji-66	150	31	been	be	AUX
aji-66	150	32	described	describe	VERB
aji-66	150	33	.	.	PUNCT
aji-66	151	1	the	the	DET
aji-66	151	2	primary	primary	ADJ
aji-66	151	3	function	function	NOUN
aji-66	151	4	of	of	ADP
aji-66	151	5	gametes	gamete	NOUN
aji-66	151	6	is	be	AUX
aji-66	151	7	to	to	PART
aji-66	151	8	find	find	VERB
aji-66	151	9	and	and	CCONJ
aji-66	151	10	fuse	fuse	VERB
aji-66	151	11	with	with	ADP
aji-66	151	12	a	a	DET
aji-66	151	13	gamete	gamete	NOUN
aji-66	151	14	of	of	ADP
aji-66	151	15	the	the	DET
aji-66	151	16	opposite	opposite	ADJ
aji-66	151	17	sex	sex	NOUN
aji-66	151	18	,	,	PUNCT
aji-66	151	19	fertilization	fertilization	NOUN
aji-66	151	20	,	,	PUNCT
aji-66	151	21	in	in	ADP
aji-66	151	22	a	a	DET
aji-66	151	23	process	process	NOUN
aji-66	151	24	that	that	PRON
aji-66	151	25	occurs	occur	VERB
aji-66	151	26	within	within	ADP
aji-66	151	27	minutes	minute	NOUN
aji-66	151	28	after	after	SCONJ
aji-66	151	29	a	a	DET
aji-66	151	30	mosquito	mosquito	NOUN
aji-66	151	31	ingests	ingest	VERB
aji-66	151	32	the	the	DET
aji-66	151	33	sexual	sexual	ADJ
aji-66	151	34	stages	stage	NOUN
aji-66	151	35	[	[	X
aji-66	151	36	15	15	NUM
aji-66	151	37	]	]	PUNCT
aji-66	151	38	.	.	PUNCT
aji-66	152	1	since	since	SCONJ
aji-66	152	2	the	the	DET
aji-66	152	3	components	component	NOUN
aji-66	152	4	of	of	ADP
aji-66	152	5	the	the	DET
aji-66	152	6	complement	complement	NOUN
aji-66	152	7	cascade	cascade	NOUN
aji-66	152	8	are	be	AUX
aji-66	152	9	present	present	ADJ
aji-66	152	10	in	in	ADP
aji-66	152	11	the	the	DET
aji-66	152	12	blood	blood	NOUN
aji-66	152	13	meal	meal	NOUN
aji-66	152	14	are	be	AUX
aji-66	152	15	still	still	ADV
aji-66	152	16	active	active	ADJ
aji-66	152	17	for	for	ADP
aji-66	152	18	minutes	minute	NOUN
aji-66	152	19	to	to	ADP
aji-66	152	20	hours	hour	NOUN
aji-66	152	21	after	after	ADP
aji-66	152	22	ingestion	ingestion	NOUN
aji-66	152	23	,	,	PUNCT
aji-66	152	24	the	the	DET
aji-66	152	25	parasite	parasite	NOUN
aji-66	152	26	has	have	AUX
aji-66	152	27	developed	develop	VERB
aji-66	152	28	protective	protective	ADJ
aji-66	152	29	mechanisms	mechanism	NOUN
aji-66	152	30	against	against	ADP
aji-66	152	31	complement	complement	NOUN
aji-66	152	32	-	-	PUNCT
aji-66	152	33	mediated	mediate	VERB
aji-66	152	34	lysis	lysis	NOUN
aji-66	152	35	[	[	X
aji-66	152	36	16	16	NUM
aji-66	152	37	]	]	PUNCT
aji-66	152	38	.	.	PUNCT
aji-66	153	1	it	it	PRON
aji-66	153	2	is	be	AUX
aji-66	153	3	therefore	therefore	ADV
aji-66	153	4	not	not	PART
aji-66	153	5	surprising	surprising	ADJ
aji-66	153	6	that	that	SCONJ
aji-66	153	7	the	the	DET
aji-66	153	8	two	two	NUM
aji-66	153	9	major	major	ADJ
aji-66	153	10	mechanisms	mechanism	NOUN
aji-66	153	11	implicated	implicate	VERB
aji-66	153	12	in	in	ADP
aji-66	153	13	antibodymediated	antibodymediate	VERB
aji-66	153	14	transmission	transmission	NOUN
aji-66	153	15	blockade	blockade	NOUN
aji-66	153	16	are	be	AUX
aji-66	153	17	directed	direct	VERB
aji-66	153	18	towards	towards	ADP
aji-66	153	19	gamete	gamete	NOUN
aji-66	153	20	surface	surface	NOUN
aji-66	153	21	proteins	protein	NOUN
aji-66	153	22	that	that	PRON
aji-66	153	23	interfere	interfere	VERB
aji-66	153	24	with	with	ADP
aji-66	153	25	fertilization	fertilization	NOUN
aji-66	153	26	and	and	CCONJ
aji-66	153	27	sensitization	sensitization	NOUN
aji-66	153	28	of	of	ADP
aji-66	153	29	gametes	gamete	NOUN
aji-66	153	30	to	to	PART
aji-66	153	31	complement	complement	NOUN
aji-66	153	32	-	-	PUNCT
aji-66	153	33	mediated	mediate	VERB
aji-66	153	34	lysis	lysis	NOUN
aji-66	153	35	[	[	X
aji-66	153	36	17	17	NUM
aji-66	153	37	]	]	PUNCT
aji-66	153	38	.	.	PUNCT
aji-66	154	1	other	other	ADJ
aji-66	154	2	mechanisms	mechanism	NOUN
aji-66	154	3	that	that	PRON
aji-66	154	4	contribute	contribute	VERB
aji-66	154	5	to	to	ADP
aji-66	154	6	transmission	transmission	NOUN
aji-66	154	7	blockage	blockage	NOUN
aji-66	154	8	may	may	AUX
aji-66	154	9	involve	involve	VERB
aji-66	154	10	a	a	DET
aji-66	154	11	cellular	cellular	ADJ
aji-66	154	12	component	component	NOUN
aji-66	154	13	,	,	PUNCT
aji-66	154	14	such	such	ADJ
aji-66	154	15	as	as	ADP
aji-66	154	16	antibody	antibody	NOUN
aji-66	154	17	-	-	PUNCT
aji-66	154	18	dependent	dependent	ADJ
aji-66	154	19	cell	cell	NOUN
aji-66	154	20	cytotoxicity	cytotoxicity	NOUN
aji-66	154	21	(	(	PUNCT
aji-66	154	22	adcc	adcc	NOUN
aji-66	154	23	)	)	PUNCT
aji-66	154	24	and	and	CCONJ
aji-66	154	25	opsonization	opsonization	NOUN
aji-66	154	26	have	have	AUX
aji-66	154	27	not	not	PART
aji-66	154	28	yet	yet	ADV
aji-66	154	29	been	be	AUX
aji-66	154	30	described	describe	VERB
aji-66	154	31	,	,	PUNCT
aji-66	154	32	but	but	CCONJ
aji-66	154	33	may	may	AUX
aji-66	154	34	occur	occur	VERB
aji-66	154	35	as	as	ADV
aji-66	154	36	well	well	ADV
aji-66	154	37	.	.	PUNCT
aji-66	155	1	the	the	DET
aji-66	155	2	major	major	ADJ
aji-66	155	3	advantage	advantage	NOUN
aji-66	155	4	of	of	ADP
aji-66	155	5	transmission	transmission	NOUN
aji-66	155	6	-	-	PUNCT
aji-66	155	7	blocking	block	VERB
aji-66	155	8	vaccines	vaccine	NOUN
aji-66	155	9	that	that	PRON
aji-66	155	10	target	target	VERB
aji-66	155	11	pre	pre	ADJ
aji-66	155	12	-	-	ADJ
aji-66	155	13	fertilization	fertilization	ADJ
aji-66	155	14	antigens	antigen	NOUN
aji-66	155	15	is	be	AUX
aji-66	155	16	that	that	SCONJ
aji-66	155	17	immune	immune	ADJ
aji-66	155	18	responses	response	NOUN
aji-66	155	19	are	be	AUX
aji-66	155	20	boosted	boost	VERB
aji-66	155	21	by	by	ADP
aji-66	155	22	each	each	DET
aji-66	155	23	subsequent	subsequent	ADJ
aji-66	155	24	natural	natural	ADJ
aji-66	155	25	infection	infection	NOUN
aji-66	155	26	.	.	PUNCT
aji-66	156	1	whether	whether	SCONJ
aji-66	156	2	boost	boost	NOUN
aji-66	156	3	will	will	AUX
aji-66	156	4	increase	increase	VERB
aji-66	156	5	the	the	DET
aji-66	156	6	titer	titer	NOUN
aji-66	156	7	of	of	ADP
aji-66	156	8	transmission	transmission	NOUN
aji-66	156	9	-	-	PUNCT
aji-66	156	10	blocking	block	VERB
aji-66	156	11	antibodies	antibody	NOUN
aji-66	156	12	or	or	CCONJ
aji-66	156	13	extend	extend	VERB
aji-66	156	14	the	the	DET
aji-66	156	15	longevity	longevity	NOUN
aji-66	156	16	of	of	ADP
aji-66	156	17	transmission	transmission	NOUN
aji-66	156	18	-	-	PUNCT
aji-66	156	19	blocking	block	VERB
aji-66	156	20	immunity	immunity	NOUN
aji-66	156	21	is	be	AUX
aji-66	156	22	yet	yet	ADV
aji-66	156	23	to	to	PART
aji-66	156	24	be	be	AUX
aji-66	156	25	determined	determine	VERB
aji-66	156	26	.	.	PUNCT
aji-66	157	1	furthermore	furthermore	ADV
aji-66	157	2	,	,	PUNCT
aji-66	157	3	antigen	antigen	ADJ
aji-66	157	4	immunogenicity	immunogenicity	NOUN
aji-66	157	5	also	also	ADV
aji-66	157	6	needs	need	VERB
aji-66	157	7	to	to	PART
aji-66	157	8	be	be	AUX
aji-66	157	9	studied	study	VERB
aji-66	157	10	since	since	SCONJ
aji-66	157	11	seroepidemiological	seroepidemiological	ADJ
aji-66	157	12	studies	study	NOUN
aji-66	157	13	indicate	indicate	VERB
aji-66	157	14	that	that	SCONJ
aji-66	157	15	less	less	ADJ
aji-66	157	16	than	than	ADP
aji-66	157	17	50	50	NUM
aji-66	157	18	%	%	NOUN
aji-66	157	19	of	of	ADP
aji-66	157	20	humans	human	NOUN
aji-66	157	21	carrying	carry	VERB
aji-66	157	22	gametocytes	gametocyte	NOUN
aji-66	157	23	contain	contain	VERB
aji-66	157	24	detectable	detectable	ADJ
aji-66	157	25	antibodies	antibody	NOUN
aji-66	157	26	to	to	ADP
aji-66	157	27	either	either	PRON
aji-66	157	28	of	of	ADP
aji-66	157	29	the	the	DET
aji-66	157	30	two	two	NUM
aji-66	157	31	lead	lead	ADJ
aji-66	157	32	pre	pre	ADJ
aji-66	157	33	-	-	ADJ
aji-66	157	34	fertilization	fertilization	ADJ
aji-66	157	35	vaccine	vaccine	NOUN
aji-66	157	36	candidates	candidate	NOUN
aji-66	157	37	,	,	PUNCT
aji-66	157	38	namely	namely	ADV
aji-66	157	39	pfs230	pfs230	VERB
aji-66	157	40	and	and	CCONJ
aji-66	157	41	pfs48/45	pfs48/45	VERB
aji-66	157	42	[	[	X
aji-66	157	43	17	17	NUM
aji-66	157	44	]	]	PUNCT
aji-66	157	45	.	.	PUNCT
aji-66	158	1	other	other	ADJ
aji-66	158	2	pre	pre	ADJ
aji-66	158	3	-	-	ADJ
aji-66	158	4	fertilization	fertilization	ADJ
aji-66	158	5	vaccine	vaccine	NOUN
aji-66	158	6	candidates	candidate	NOUN
aji-66	158	7	are	be	AUX
aji-66	158	8	pfs2400	pfs2400	NOUN
aji-66	158	9	,	,	PUNCT
aji-66	158	10	pfs40	pfs40	NOUN
aji-66	158	11	and	and	CCONJ
aji-66	158	12	pfg27/25	pfg27/25	X
aji-66	158	13	[	[	X
aji-66	158	14	18	18	NUM
aji-66	158	15	]	]	SYM
aji-66	158	16	.	.	PUNCT
aji-66	159	1	3.1	3.1	NUM
aji-66	159	2	immune	immune	ADJ
aji-66	159	3	response	response	NOUN
aji-66	159	4	to	to	ADP
aji-66	159	5	pfs25	pfs25	NOUN
aji-66	159	6	malaria	malaria	NOUN
aji-66	159	7	vaccines	vaccine	NOUN
aji-66	159	8	that	that	PRON
aji-66	159	9	target	target	VERB
aji-66	159	10	both	both	CCONJ
aji-66	159	11	human	human	ADJ
aji-66	159	12	and	and	CCONJ
aji-66	159	13	mosquito	mosquito	ADJ
aji-66	159	14	infections	infection	NOUN
aji-66	159	15	have	have	VERB
aji-66	159	16	the	the	DET
aji-66	159	17	potential	potential	NOUN
aji-66	159	18	to	to	PART
aji-66	159	19	impact	impact	VERB
aji-66	159	20	malaria	malaria	NOUN
aji-66	159	21	control	control	NOUN
aji-66	159	22	.	.	PUNCT
aji-66	160	1	the	the	DET
aji-66	160	2	importance	importance	NOUN
aji-66	160	3	of	of	ADP
aji-66	160	4	developing	develop	VERB
aji-66	160	5	such	such	DET
aji-66	160	6	a	a	DET
aji-66	160	7	vaccine	vaccine	NOUN
aji-66	160	8	is	be	AUX
aji-66	160	9	underscored	underscore	VERB
aji-66	160	10	in	in	ADP
aji-66	160	11	a	a	DET
aji-66	160	12	who	who	PRON
aji-66	160	13	world	world	NOUN
aji-66	160	14	malaria	malaria	NOUN
aji-66	160	15	report	report	NOUN
aji-66	160	16	,	,	PUNCT
aji-66	160	17	which	which	PRON
aji-66	160	18	indicates	indicate	VERB
aji-66	160	19	stagnation	stagnation	NOUN
aji-66	160	20	in	in	ADP
aji-66	160	21	the	the	DET
aji-66	160	22	progress	progress	NOUN
aji-66	160	23	towards	towards	ADP
aji-66	160	24	reducing	reduce	VERB
aji-66	160	25	global	global	ADJ
aji-66	160	26	malaria	malaria	NOUN
aji-66	160	27	cases	case	NOUN
aji-66	160	28	since	since	SCONJ
aji-66	160	29	2015	2015	NUM
aji-66	160	30	[	[	X
aji-66	160	31	19	19	NUM
aji-66	160	32	]	]	PUNCT
aji-66	160	33	.	.	PUNCT
aji-66	161	1	the	the	DET
aji-66	161	2	malaria	malaria	NOUN
aji-66	161	3	vaccine	vaccine	NOUN
aji-66	161	4	rts	rt	NOUN
aji-66	161	5	,	,	PUNCT
aji-66	161	6	s	s	AUX
aji-66	161	7	,	,	PUNCT
aji-66	161	8	which	which	PRON
aji-66	161	9	targets	target	VERB
aji-66	161	10	human	human	ADJ
aji-66	161	11	infections	infection	NOUN
aji-66	161	12	as	as	SCONJ
aji-66	161	13	indicated	indicate	VERB
aji-66	161	14	by	by	ADP
aji-66	161	15	its	its	PRON
aji-66	161	16	impact	impact	NOUN
aji-66	161	17	on	on	ADP
aji-66	161	18	clinical	clinical	ADJ
aji-66	161	19	disease	disease	NOUN
aji-66	161	20	,	,	PUNCT
aji-66	161	21	has	have	AUX
aji-66	161	22	completed	complete	VERB
aji-66	161	23	phase	phase	NOUN
aji-66	161	24	3	3	NUM
aji-66	161	25	testing	testing	NOUN
aji-66	161	26	and	and	CCONJ
aji-66	161	27	is	be	AUX
aji-66	161	28	in	in	ADP
aji-66	161	29	pilot	pilot	NOUN
aji-66	161	30	implementation	implementation	NOUN
aji-66	161	31	studies	study	NOUN
aji-66	161	32	in	in	ADP
aji-66	161	33	three	three	NUM
aji-66	161	34	african	african	ADJ
aji-66	161	35	countries	country	NOUN
aji-66	161	36	,	,	PUNCT
aji-66	161	37	namely	namely	ADV
aji-66	161	38	kenya	kenya	NOUN
aji-66	161	39	,	,	PUNCT
aji-66	161	40	ghana	ghana	PROPN
aji-66	161	41	and	and	CCONJ
aji-66	161	42	malawi	malawi	PROPN
aji-66	162	1	[	[	X
aji-66	162	2	20,21	20,21	NUM
aji-66	162	3	]	]	PUNCT
aji-66	162	4	.	.	PUNCT
aji-66	163	1	efforts	effort	NOUN
aji-66	163	2	to	to	PART
aji-66	163	3	develop	develop	VERB
aji-66	163	4	a	a	DET
aji-66	163	5	vaccine	vaccine	NOUN
aji-66	163	6	that	that	PRON
aji-66	163	7	disrupts	disrupt	VERB
aji-66	163	8	mosquito	mosquito	ADJ
aji-66	163	9	infection	infection	NOUN
aji-66	163	10	,	,	PUNCT
aji-66	163	11	known	know	VERB
aji-66	163	12	as	as	ADP
aji-66	163	13	a	a	DET
aji-66	163	14	malaria	malaria	NOUN
aji-66	163	15	transmission	transmission	NOUN
aji-66	163	16	-	-	PUNCT
aji-66	163	17	blocking	block	VERB
aji-66	163	18	vaccine	vaccine	NOUN
aji-66	163	19	(	(	PUNCT
aji-66	163	20	tbv	tbv	PROPN
aji-66	163	21	)	)	PUNCT
aji-66	163	22	,	,	PUNCT
aji-66	163	23	have	have	AUX
aji-66	163	24	been	be	AUX
aji-66	163	25	ongoing	ongoing	ADJ
aji-66	163	26	since	since	SCONJ
aji-66	163	27	the	the	DET
aji-66	163	28	reporting	reporting	NOUN
aji-66	163	29	of	of	ADP
aji-66	163	30	induced	induced	ADJ
aji-66	163	31	tbvinduced	tbvinduced	ADJ
aji-66	163	32	immunity	immunity	NOUN
aji-66	163	33	in	in	ADP
aji-66	163	34	chickens	chicken	NOUN
aji-66	163	35	against	against	ADP
aji-66	163	36	plasmodium	plasmodium	NOUN
aji-66	163	37	gallinaceum	gallinaceum	NOUN
aji-66	163	38	in	in	ADP
aji-66	163	39	1976	1976	NUM
aji-66	163	40	[	[	X
aji-66	163	41	22	22	NUM
aji-66	163	42	]	]	PUNCT
aji-66	163	43	.	.	PUNCT
aji-66	164	1	the	the	DET
aji-66	164	2	pace	pace	NOUN
aji-66	164	3	of	of	ADP
aji-66	164	4	malaria	malaria	NOUN
aji-66	164	5	tbv	tbv	PRON
aji-66	164	6	development	development	NOUN
aji-66	164	7	,	,	PUNCT
aji-66	164	8	until	until	ADP
aji-66	164	9	recently	recently	ADV
aji-66	164	10	,	,	PUNCT
aji-66	164	11	has	have	AUX
aji-66	164	12	been	be	AUX
aji-66	164	13	hindered	hinder	VERB
aji-66	164	14	by	by	ADP
aji-66	164	15	the	the	DET
aji-66	164	16	lack	lack	NOUN
aji-66	164	17	of	of	ADP
aji-66	164	18	capacity	capacity	NOUN
aji-66	164	19	to	to	PART
aji-66	164	20	produce	produce	VERB
aji-66	164	21	candidate	candidate	NOUN
aji-66	164	22	antigens	antigen	NOUN
aji-66	164	23	for	for	ADP
aji-66	164	24	clinical	clinical	ADJ
aji-66	164	25	testing	testing	NOUN
aji-66	164	26	[	[	X
aji-66	164	27	22	22	NUM
aji-66	164	28	]	]	PUNCT
aji-66	164	29	.	.	PUNCT
aji-66	165	1	currently	currently	ADV
aji-66	165	2	,	,	PUNCT
aji-66	165	3	clinical	clinical	ADJ
aji-66	165	4	testing	testing	NOUN
aji-66	165	5	is	be	AUX
aji-66	165	6	are	be	AUX
aji-66	165	7	limited	limit	VERB
aji-66	165	8	to	to	ADP
aji-66	165	9	pfs25	pfs25	PROPN
aji-66	165	10	,	,	PUNCT
aji-66	165	11	a	a	DET
aji-66	165	12	p.	p.	NOUN
aji-66	165	13	falciparum	falciparum	NOUN
aji-66	165	14	-	-	PUNCT
aji-66	165	15	specific	specific	ADJ
aji-66	165	16	antigen	antigen	NOUN
aji-66	165	17	.	.	PUNCT
aji-66	166	1	pfs25	pfs25	NOUN
aji-66	166	2	is	be	AUX
aji-66	166	3	a	a	DET
aji-66	166	4	25	25	NUM
aji-66	166	5	kda	kda	NOUN
aji-66	166	6	sexual	sexual	ADJ
aji-66	166	7	-	-	PUNCT
aji-66	166	8	stage	stage	NOUN
aji-66	166	9	protein	protein	NOUN
aji-66	166	10	present	present	ADJ
aji-66	166	11	on	on	ADP
aji-66	166	12	the	the	DET
aji-66	166	13	p.	p.	NOUN
aji-66	166	14	falciparum	falciparum	NOUN
aji-66	166	15	zygote	zygote	NOUN
aji-66	166	16	and	and	CCONJ
aji-66	166	17	ookinete	ookinete	ADJ
aji-66	166	18	surface	surface	NOUN
aji-66	166	19	in	in	ADP
aji-66	166	20	the	the	DET
aji-66	166	21	mosquito	mosquito	ADJ
aji-66	166	22	midgut	midgut	NOUN
aji-66	166	23	.	.	PUNCT
aji-66	167	1	the	the	DET
aji-66	167	2	leading	lead	VERB
aji-66	167	3	pfs25	pfs25	NOUN
aji-66	167	4	tbv	tbv	PRON
aji-66	167	5	is	be	AUX
aji-66	167	6	a	a	DET
aji-66	167	7	chemically	chemically	ADV
aji-66	167	8	conjugated	conjugate	VERB
aji-66	167	9	vaccine	vaccine	NOUN
aji-66	167	10	comprising	comprising	NOUN
aji-66	167	11	of	of	ADP
aji-66	167	12	a	a	DET
aji-66	167	13	pichia	pichia	NOUN
aji-66	167	14	pastoris	pastoris	NOUN
aji-66	167	15	expressed	express	VERB
aji-66	167	16	pfs25	pfs25	PROPN
aji-66	167	17	and	and	CCONJ
aji-66	167	18	the	the	DET
aji-66	167	19	carrier	carrier	NOUN
aji-66	167	20	protein	protein	NOUN
aji-66	167	21	exoprotein	exoprotein	ADV
aji-66	167	22	a	a	DET
aji-66	167	23	(	(	PUNCT
aji-66	167	24	epa	epa	PROPN
aji-66	167	25	)	)	PUNCT
aji-66	167	26	or	or	CCONJ
aji-66	167	27	a	a	DET
aji-66	167	28	recombinant	recombinant	ADJ
aji-66	167	29	detoxified	detoxify	VERB
aji-66	167	30	form	form	NOUN
aji-66	167	31	of	of	ADP
aji-66	167	32	pseudomonas	pseudomona	NOUN
aji-66	167	33	aeruginosa	aeruginosa	NOUN
aji-66	167	34	exotoxin	exotoxin	NOUN
aji-66	167	35	a9	a9	PROPN
aji-66	167	36	.	.	PUNCT
aji-66	168	1	the	the	DET
aji-66	168	2	pfs25	pfs25	PROPN
aji-66	168	3	-	-	PUNCT
aji-66	168	4	epa	epa	PROPN
aji-66	168	5	conjugate	conjugate	NOUN
aji-66	168	6	has	have	VERB
aji-66	168	7	the	the	DET
aji-66	168	8	biophysical	biophysical	ADJ
aji-66	168	9	characteristics	characteristic	NOUN
aji-66	168	10	of	of	ADP
aji-66	168	11	a	a	DET
aji-66	168	12	nanoparticle	nanoparticle	NOUN
aji-66	168	13	with	with	ADP
aji-66	168	14	a	a	DET
aji-66	168	15	size	size	NOUN
aji-66	168	16	similar	similar	ADJ
aji-66	168	17	to	to	ADP
aji-66	168	18	the	the	DET
aji-66	168	19	hepatitis	hepatitis	PROPN
aji-66	168	20	b	b	PROPN
aji-66	168	21	virus	virus	NOUN
aji-66	168	22	-	-	PUNCT
aji-66	168	23	like	like	ADP
aji-66	168	24	-	-	PUNCT
aji-66	168	25	particle	particle	NOUN
aji-66	168	26	used	use	VERB
aji-66	168	27	in	in	ADP
aji-66	168	28	rts	rt	NOUN
aji-66	168	29	,	,	PUNCT
aji-66	168	30	s	s	PART
aji-66	168	31	[	[	X
aji-66	168	32	23	23	NUM
aji-66	168	33	]	]	PUNCT
aji-66	168	34	.	.	PUNCT
aji-66	169	1	ex	ex	PRON
aji-66	169	2	vivo	vivo	ADJ
aji-66	169	3	standard	standard	ADJ
aji-66	169	4	membrane	membrane	NOUN
aji-66	169	5	feeding	feeding	NOUN
aji-66	169	6	assays	assay	NOUN
aji-66	169	7	(	(	PUNCT
aji-66	169	8	smfa	smfa	NOUN
aji-66	169	9	)	)	PUNCT
aji-66	169	10	during	during	ADP
aji-66	169	11	phase	phase	NOUN
aji-66	169	12	1	1	NUM
aji-66	169	13	trials	trial	NOUN
aji-66	169	14	of	of	ADP
aji-66	169	15	pfs25	pfs25	PROPN
aji-66	169	16	-	-	PUNCT
aji-66	169	17	epa	epa	PROPN
aji-66	169	18	conjugates	conjugate	NOUN
aji-66	169	19	formulated	formulate	VERB
aji-66	169	20	with	with	ADP
aji-66	169	21	alhydrogel	alhydrogel	NOUN
aji-66	169	22	™	™	PROPN
aji-66	169	23	,	,	PUNCT
aji-66	169	24	an	an	DET
aji-66	169	25	aluminium	aluminium	NOUN
aji-66	169	26	-	-	PUNCT
aji-66	169	27	based	base	VERB
aji-66	169	28	adjuvant	adjuvant	NOUN
aji-66	169	29	conducted	conduct	VERB
aji-66	169	30	in	in	ADP
aji-66	169	31	the	the	DET
aji-66	169	32	united	united	PROPN
aji-66	169	33	states	states	PROPN
aji-66	169	34	of	of	ADP
aji-66	169	35	america	america	PROPN
aji-66	169	36	,	,	PUNCT
aji-66	169	37	and	and	CCONJ
aji-66	169	38	mali	mali	PROPN
aji-66	169	39	revealed	reveal	VERB
aji-66	169	40	that	that	SCONJ
aji-66	169	41	four	four	NUM
aji-66	169	42	doses	dose	NOUN
aji-66	169	43	are	be	AUX
aji-66	169	44	required	require	VERB
aji-66	169	45	to	to	PART
aji-66	169	46	generate	generate	VERB
aji-66	169	47	antibody	antibody	NOUN
aji-66	169	48	titers	titer	NOUN
aji-66	169	49	that	that	PRON
aji-66	169	50	significantly	significantly	ADV
aji-66	169	51	reduce	reduce	VERB
aji-66	169	52	parasite	parasite	NOUN
aji-66	169	53	transmission	transmission	NOUN
aji-66	170	1	[	[	X
aji-66	170	2	22	22	NUM
aji-66	170	3	]	]	PUNCT
aji-66	170	4	.	.	PUNCT
aji-66	171	1	however	however	ADV
aji-66	171	2	,	,	PUNCT
aji-66	171	3	poor	poor	ADJ
aji-66	171	4	clinical	clinical	ADJ
aji-66	171	5	trial	trial	NOUN
aji-66	171	6	results	result	NOUN
aji-66	171	7	have	have	AUX
aji-66	171	8	halted	halt	VERB
aji-66	171	9	the	the	DET
aji-66	171	10	development	development	NOUN
aji-66	171	11	of	of	ADP
aji-66	171	12	pfs25epa	pfs25epa	NOUN
aji-66	171	13	as	as	ADP
aji-66	171	14	a	a	DET
aji-66	171	15	stand	stand	NOUN
aji-66	171	16	-	-	PUNCT
aji-66	171	17	alone	alone	NOUN
aji-66	171	18	tbv	tbv	PROPN
aji-66	171	19	.	.	PUNCT
aji-66	172	1	which	which	PRON
aji-66	172	2	can	can	AUX
aji-66	172	3	probably	probably	ADV
aji-66	172	4	be	be	AUX
aji-66	172	5	tackled	tackle	VERB
aji-66	172	6	by	by	ADP
aji-66	172	7	using	use	VERB
aji-66	172	8	the	the	DET
aji-66	172	9	correct	correct	ADJ
aji-66	172	10	carrier	carrier	NOUN
aji-66	172	11	protein	protein	NOUN
aji-66	172	12	.	.	PUNCT
aji-66	173	1	wangai	wangai	INTJ
aji-66	173	2	et	et	PROPN
aji-66	173	3	al	al	PROPN
aji-66	173	4	.	.	PROPN
aji-66	173	5	;	;	PUNCT
aji-66	173	6	aji	aji	PROPN
aji-66	173	7	,	,	PUNCT
aji-66	173	8	4(1	4(1	NOUN
aji-66	173	9	):	):	PUNCT
aji-66	173	10	77	77	NUM
aji-66	173	11	-	-	SYM
aji-66	173	12	84	84	NUM
aji-66	173	13	,	,	PUNCT
aji-66	173	14	2021	2021	NUM
aji-66	173	15	;	;	PUNCT
aji-66	173	16	article	article	NOUN
aji-66	173	17	no.aji.69854	no.aji.69854	NOUN
aji-66	173	18	80	80	NUM
aji-66	173	19	3.2	3.2	NUM
aji-66	173	20	immune	immune	ADJ
aji-66	173	21	response	response	NOUN
aji-66	173	22	to	to	ADP
aji-66	173	23	pfs230	pfs230	PROPN
aji-66	173	24	and	and	CCONJ
aji-66	173	25	pfs48/45	pfs48/45	VERB
aji-66	173	26	another	another	DET
aji-66	173	27	family	family	NOUN
aji-66	173	28	of	of	ADP
aji-66	173	29	sexual	sexual	ADJ
aji-66	173	30	-	-	PUNCT
aji-66	173	31	stage	stage	NOUN
aji-66	173	32	proteins	protein	NOUN
aji-66	173	33	with	with	ADP
aji-66	173	34	cysteine	cysteine	ADJ
aji-66	173	35	-	-	PUNCT
aji-66	173	36	rich	rich	ADJ
aji-66	173	37	domains	domain	NOUN
aji-66	173	38	includes	include	VERB
aji-66	173	39	the	the	DET
aji-66	173	40	antigens	antigen	NOUN
aji-66	173	41	pfs230	pfs230	VERB
aji-66	173	42	and	and	CCONJ
aji-66	173	43	pfs48/45	pfs48/45	NOUN
aji-66	173	44	that	that	PRON
aji-66	173	45	have	have	AUX
aji-66	173	46	been	be	AUX
aji-66	173	47	targeted	target	VERB
aji-66	173	48	for	for	ADP
aji-66	173	49	tbv	tbv	DET
aji-66	173	50	development	development	NOUN
aji-66	173	51	.	.	PUNCT
aji-66	174	1	however	however	ADV
aji-66	174	2	,	,	PUNCT
aji-66	174	3	until	until	ADP
aji-66	174	4	recently	recently	ADV
aji-66	174	5	,	,	PUNCT
aji-66	174	6	there	there	PRON
aji-66	174	7	was	be	VERB
aji-66	174	8	no	no	DET
aji-66	174	9	recombinant	recombinant	ADJ
aji-66	174	10	antigen	antigen	ADJ
aji-66	174	11	preparation	preparation	NOUN
aji-66	174	12	available	available	ADJ
aji-66	174	13	with	with	ADP
aji-66	174	14	the	the	DET
aji-66	174	15	identity	identity	NOUN
aji-66	174	16	,	,	PUNCT
aji-66	174	17	purity	purity	NOUN
aji-66	174	18	,	,	PUNCT
aji-66	174	19	and	and	CCONJ
aji-66	174	20	quality	quality	NOUN
aji-66	174	21	necessary	necessary	ADJ
aji-66	174	22	for	for	ADP
aji-66	174	23	human	human	ADJ
aji-66	174	24	clinical	clinical	ADJ
aji-66	174	25	trials	trial	NOUN
aji-66	174	26	[	[	X
aji-66	174	27	24	24	NUM
aji-66	174	28	]	]	PUNCT
aji-66	174	29	.	.	PUNCT
aji-66	175	1	of	of	ADP
aji-66	175	2	the	the	DET
aji-66	175	3	two	two	NUM
aji-66	175	4	,	,	PUNCT
aji-66	175	5	pfs230	pfs230	PROPN
aji-66	175	6	cysteine	cysteine	ADJ
aji-66	175	7	-	-	PUNCT
aji-66	175	8	rich	rich	ADJ
aji-66	175	9	domain	domain	NOUN
aji-66	175	10	was	be	AUX
aji-66	175	11	the	the	DET
aji-66	175	12	first	first	ADJ
aji-66	175	13	antigen	antigen	NOUN
aji-66	175	14	to	to	PART
aji-66	175	15	be	be	AUX
aji-66	175	16	produced	produce	VERB
aji-66	175	17	.	.	PUNCT
aji-66	176	1	it	it	PRON
aji-66	176	2	consists	consist	VERB
aji-66	176	3	of	of	ADP
aji-66	176	4	a	a	DET
aji-66	176	5	230	230	NUM
aji-66	176	6	kda	kda	NOUN
aji-66	176	7	sexual	sexual	ADJ
aji-66	176	8	-	-	PUNCT
aji-66	176	9	stage	stage	NOUN
aji-66	176	10	protein	protein	NOUN
aji-66	176	11	that	that	PRON
aji-66	176	12	is	be	AUX
aji-66	176	13	composed	compose	VERB
aji-66	176	14	of	of	ADP
aji-66	176	15	fourteen	fourteen	NUM
aji-66	176	16	6	6	NUM
aji-66	176	17	-	-	PUNCT
aji-66	176	18	cysteine	cysteine	NOUN
aji-66	176	19	-	-	PUNCT
aji-66	176	20	rich	rich	ADJ
aji-66	176	21	domains	domain	NOUN
aji-66	176	22	that	that	PRON
aji-66	176	23	suitable	suitable	ADJ
aji-66	176	24	for	for	ADP
aji-66	176	25	human	human	ADJ
aji-66	176	26	clinical	clinical	ADJ
aji-66	176	27	testing	testing	NOUN
aji-66	176	28	[	[	X
aji-66	176	29	25	25	NUM
aji-66	176	30	]	]	PUNCT
aji-66	176	31	.	.	PUNCT
aji-66	177	1	recombinant	recombinant	ADJ
aji-66	177	2	pfs230	pfs230	PROPN
aji-66	177	3	domain	domain	NOUN
aji-66	177	4	1	1	NUM
aji-66	177	5	(	(	PUNCT
aji-66	177	6	pfs230d1	pfs230d1	NOUN
aji-66	177	7	m	m	NOUN
aji-66	177	8	)	)	PUNCT
aji-66	177	9	is	be	AUX
aji-66	177	10	wellcharacterized	wellcharacterize	VERB
aji-66	177	11	and	and	CCONJ
aji-66	177	12	has	have	AUX
aji-66	177	13	shown	show	VERB
aji-66	177	14	to	to	PART
aji-66	177	15	induce	induce	VERB
aji-66	177	16	transmission	transmission	NOUN
aji-66	177	17	-	-	PUNCT
aji-66	177	18	blocking	block	VERB
aji-66	177	19	antibodies	antibody	NOUN
aji-66	177	20	in	in	ADP
aji-66	177	21	small	small	ADJ
aji-66	177	22	animals	animal	NOUN
aji-66	177	23	using	use	VERB
aji-66	177	24	the	the	DET
aji-66	177	25	smfa16	smfa16	NOUN
aji-66	178	1	[	[	X
aji-66	178	2	24	24	NUM
aji-66	178	3	]	]	PUNCT
aji-66	178	4	.	.	PUNCT
aji-66	179	1	parasite	parasite	NOUN
aji-66	179	2	-	-	PUNCT
aji-66	179	3	derived	derive	VERB
aji-66	179	4	antigen	antigen	NOUN
aji-66	179	5	(	(	PUNCT
aji-66	179	6	pfs23016a	pfs23016a	NOUN
aji-66	179	7	)	)	PUNCT
aji-66	179	8	has	have	AUX
aji-66	179	9	been	be	AUX
aji-66	179	10	shown	show	VERB
aji-66	179	11	to	to	PART
aji-66	179	12	induce	induce	VERB
aji-66	179	13	the	the	DET
aji-66	179	14	production	production	NOUN
aji-66	179	15	of	of	ADP
aji-66	179	16	transmission	transmission	NOUN
aji-66	179	17	-	-	PUNCT
aji-66	179	18	blocking	block	VERB
aji-66	179	19	monoclonal	monoclonal	NOUN
aji-66	179	20	antibodies	antibody	NOUN
aji-66	179	21	(	(	PUNCT
aji-66	179	22	4f12	4f12	NUM
aji-66	179	23	)	)	PUNCT
aji-66	179	24	.	.	PUNCT
aji-66	180	1	a	a	DET
aji-66	180	2	phase	phase	NOUN
aji-66	180	3	1	1	NUM
aji-66	180	4	safety	safety	NOUN
aji-66	180	5	and	and	CCONJ
aji-66	180	6	immunogenicity	immunogenicity	NOUN
aji-66	180	7	study	study	NOUN
aji-66	180	8	evaluating	evaluate	VERB
aji-66	180	9	pfs230	pfs230	PROPN
aji-66	180	10	d1epa	d1epa	NOUN
aji-66	180	11	nanoparticles	nanoparticle	NOUN
aji-66	180	12	formulated	formulate	VERB
aji-66	180	13	on	on	ADP
aji-66	180	14	alhydrogel	alhydrogel	NOUN
aji-66	180	15	™	™	NOUN
aji-66	180	16	has	have	AUX
aji-66	180	17	been	be	AUX
aji-66	180	18	completed	complete	VERB
aji-66	180	19	[	[	PUNCT
aji-66	180	20	24	24	NUM
aji-66	180	21	]	]	PUNCT
aji-66	180	22	.	.	PUNCT
aji-66	181	1	pfs230d1	pfs230d1	NOUN
aji-66	181	2	m	m	NOUN
aji-66	181	3	is	be	AUX
aji-66	181	4	conjugated	conjugate	VERB
aji-66	181	5	chemically	chemically	ADV
aji-66	181	6	to	to	ADP
aji-66	181	7	epa	epa	PROPN
aji-66	181	8	forming	form	VERB
aji-66	181	9	nanoparticles	nanoparticle	NOUN
aji-66	181	10	with	with	ADP
aji-66	181	11	a	a	DET
aji-66	181	12	similar	similar	ADJ
aji-66	181	13	size	size	NOUN
aji-66	181	14	as	as	ADP
aji-66	181	15	hepatitis	hepatitis	PROPN
aji-66	181	16	b	b	PROPN
aji-66	181	17	virus10	virus10	NOUN
aji-66	181	18	.	.	PUNCT
aji-66	182	1	3.3	3.3	NUM
aji-66	182	2	post	post	NOUN
aji-66	182	3	fertilization	fertilization	NOUN
aji-66	182	4	target	target	NOUN
aji-66	182	5	antigens	antigen	NOUN
aji-66	182	6	several	several	ADJ
aji-66	182	7	post	post	ADJ
aji-66	182	8	-	-	ADJ
aji-66	182	9	fertilization	fertilization	ADJ
aji-66	182	10	target	target	NOUN
aji-66	182	11	antigens	antigen	NOUN
aji-66	182	12	have	have	AUX
aji-66	182	13	been	be	AUX
aji-66	182	14	described	describe	VERB
aji-66	182	15	,	,	PUNCT
aji-66	182	16	including	include	VERB
aji-66	182	17	pfs28	pfs28	PROPN
aji-66	182	18	(	(	PUNCT
aji-66	182	19	d&y	d&y	PROPN
aji-66	182	20	&	&	CCONJ
aji-66	182	21	kaslow	kaslow	PROPN
aji-66	182	22	.	.	PUNCT
aji-66	183	1	submitted	submit	VERB
aji-66	183	2	)	)	PUNCT
aji-66	183	3	,	,	PUNCT
aji-66	183	4	pfs25	pfs25	PROPN
aji-66	183	5	.	.	PUNCT
aji-66	184	1	chitinase	chitinase	NOUN
aji-66	184	2	and	and	CCONJ
aji-66	184	3	mosquito	mosquito	ADJ
aji-66	184	4	midgut	midgut	NOUN
aji-66	184	5	late	late	ADJ
aji-66	184	6	trypsin	trypsin	NOUN
aji-66	185	1	[	[	X
aji-66	185	2	26,27	26,27	NUM
aji-66	185	3	]	]	PUNCT
aji-66	185	4	.	.	PUNCT
aji-66	186	1	the	the	DET
aji-66	186	2	two	two	NUM
aji-66	186	3	major	major	ADJ
aji-66	186	4	mechanisms	mechanism	NOUN
aji-66	186	5	mediating	mediate	VERB
aji-66	186	6	blockade	blockade	NOUN
aji-66	186	7	post	post	ADJ
aji-66	186	8	-	-	ADJ
aji-66	186	9	fertilization	fertilization	NOUN
aji-66	186	10	involve	involve	VERB
aji-66	186	11	arresting	arrest	VERB
aji-66	186	12	the	the	DET
aji-66	186	13	morphological	morphological	ADJ
aji-66	186	14	transformation	transformation	NOUN
aji-66	186	15	of	of	ADP
aji-66	186	16	the	the	DET
aji-66	186	17	round	round	ADJ
aji-66	186	18	,	,	PUNCT
aji-66	186	19	sedentary	sedentary	ADJ
aji-66	186	20	zygote	zygote	X
aji-66	186	21	to	to	ADP
aji-66	186	22	the	the	DET
aji-66	186	23	oblong	oblong	ADJ
aji-66	186	24	,	,	PUNCT
aji-66	186	25	motile	motile	NOUN
aji-66	186	26	ookinete	ookinete	NOUN
aji-66	186	27	and	and	CCONJ
aji-66	186	28	preventing	prevent	VERB
aji-66	186	29	the	the	DET
aji-66	186	30	egress	egress	NOUN
aji-66	186	31	of	of	ADP
aji-66	186	32	the	the	DET
aji-66	186	33	ookinete	ookinete	NOUN
aji-66	186	34	from	from	ADP
aji-66	186	35	the	the	DET
aji-66	186	36	blood	blood	NOUN
aji-66	186	37	meal	meal	NOUN
aji-66	186	38	to	to	ADP
aji-66	186	39	the	the	DET
aji-66	186	40	midgut	midgut	NOUN
aji-66	187	1	epithelium	epithelium	NOUN
aji-66	187	2	basal	basal	ADJ
aji-66	187	3	lamina	lamina	NOUN
aji-66	188	1	[	[	X
aji-66	188	2	11	11	NUM
aji-66	188	3	]	]	PUNCT
aji-66	188	4	.	.	PUNCT
aji-66	189	1	preliminary	preliminary	ADJ
aji-66	189	2	evidence	evidence	NOUN
aji-66	189	3	suggests	suggest	VERB
aji-66	189	4	that	that	SCONJ
aji-66	189	5	transmission	transmission	NOUN
aji-66	189	6	-	-	PUNCT
aji-66	189	7	blocking	block	VERB
aji-66	189	8	antibodies	antibody	NOUN
aji-66	189	9	may	may	AUX
aji-66	189	10	also	also	ADV
aji-66	189	11	interfere	interfere	VERB
aji-66	189	12	with	with	ADP
aji-66	189	13	normal	normal	ADJ
aji-66	189	14	sporozoite	sporozoite	NOUN
aji-66	189	15	development	development	NOUN
aji-66	189	16	.	.	PUNCT
aji-66	190	1	however	however	ADV
aji-66	190	2	,	,	PUNCT
aji-66	190	3	the	the	DET
aji-66	190	4	exact	exact	ADJ
aji-66	190	5	mechanism(s	mechanism(s	NOUN
aji-66	190	6	)	)	PUNCT
aji-66	190	7	by	by	ADP
aji-66	190	8	which	which	PRON
aji-66	190	9	this	this	PRON
aji-66	190	10	occurs	occur	VERB
aji-66	190	11	is	be	AUX
aji-66	190	12	not	not	PART
aji-66	190	13	yet	yet	ADV
aji-66	190	14	known	know	VERB
aji-66	190	15	though	though	SCONJ
aji-66	190	16	there	there	PRON
aji-66	190	17	is	be	VERB
aji-66	190	18	increased	increase	VERB
aji-66	190	19	gametocyte	gametocyte	NOUN
aji-66	190	20	clearance	clearance	NOUN
aji-66	190	21	and	and	CCONJ
aji-66	190	22	impaired	impaired	ADJ
aji-66	190	23	development	development	NOUN
aji-66	190	24	in	in	ADP
aji-66	190	25	later	later	ADJ
aji-66	190	26	stages	stage	NOUN
aji-66	190	27	[	[	X
aji-66	190	28	28	28	NUM
aji-66	190	29	]	]	PUNCT
aji-66	190	30	.	.	PUNCT
aji-66	191	1	the	the	DET
aji-66	191	2	major	major	ADJ
aji-66	191	3	advantages	advantage	NOUN
aji-66	191	4	of	of	ADP
aji-66	191	5	postfertilization	postfertilization	NOUN
aji-66	191	6	target	target	NOUN
aji-66	191	7	antigens	antigen	NOUN
aji-66	191	8	are	be	AUX
aji-66	191	9	immunogenicity	immunogenicity	NOUN
aji-66	191	10	and	and	CCONJ
aji-66	191	11	limited	limited	ADJ
aji-66	191	12	pre	pre	ADJ
aji-66	191	13	-	-	ADJ
aji-66	191	14	existing	existing	ADJ
aji-66	191	15	antigenic	antigenic	ADJ
aji-66	191	16	diversity	diversity	NOUN
aji-66	191	17	,	,	PUNCT
aji-66	191	18	unequivocally	unequivocally	ADV
aji-66	191	19	reflecting	reflect	VERB
aji-66	191	20	the	the	DET
aji-66	191	21	lack	lack	NOUN
aji-66	191	22	of	of	ADP
aji-66	191	23	prior	prior	ADJ
aji-66	191	24	immune	immune	ADJ
aji-66	191	25	selection	selection	NOUN
aji-66	191	26	on	on	ADP
aji-66	191	27	these	these	DET
aji-66	191	28	antigens	antigen	NOUN
aji-66	191	29	.	.	PUNCT
aji-66	192	1	since	since	SCONJ
aji-66	192	2	these	these	DET
aji-66	192	3	target	target	NOUN
aji-66	192	4	antigens	antigen	NOUN
aji-66	192	5	are	be	AUX
aji-66	192	6	expressed	express	VERB
aji-66	192	7	late	late	ADV
aji-66	192	8	in	in	ADP
aji-66	192	9	sexual	sexual	ADJ
aji-66	192	10	sporogonic	sporogonic	ADJ
aji-66	192	11	development	development	NOUN
aji-66	192	12	,	,	PUNCT
aji-66	192	13	high	high	ADJ
aji-66	192	14	antibody	antibody	NOUN
aji-66	192	15	titers	titer	NOUN
aji-66	192	16	may	may	AUX
aji-66	192	17	be	be	AUX
aji-66	192	18	required	require	VERB
aji-66	192	19	to	to	PART
aji-66	192	20	account	account	VERB
aji-66	192	21	for	for	ADP
aji-66	192	22	antibody	antibody	NOUN
aji-66	192	23	degradation	degradation	NOUN
aji-66	192	24	from	from	ADP
aji-66	192	25	proteolysis	proteolysis	NOUN
aji-66	192	26	in	in	ADP
aji-66	192	27	the	the	DET
aji-66	192	28	blood	blood	NOUN
aji-66	192	29	meal	meal	NOUN
aji-66	192	30	and	and	CCONJ
aji-66	192	31	boosting	boost	VERB
aji-66	192	32	after	after	SCONJ
aji-66	192	33	a	a	DET
aji-66	192	34	natural	natural	ADJ
aji-66	192	35	infection	infection	NOUN
aji-66	192	36	may	may	AUX
aji-66	192	37	not	not	PART
aji-66	192	38	occur	occur	VERB
aji-66	192	39	.	.	PUNCT
aji-66	193	1	4	4	X
aji-66	193	2	.	.	X
aji-66	193	3	first	first	ADJ
aji-66	193	4	generation	generation	NOUN
aji-66	193	5	transmissionblocking	transmissionblocking	NOUN
aji-66	193	6	vaccine	vaccine	NOUN
aji-66	193	7	,	,	PUNCT
aji-66	193	8	tbv25h	tbv25h	VERB
aji-66	193	9	one	one	NUM
aji-66	193	10	of	of	ADP
aji-66	193	11	the	the	DET
aji-66	193	12	most	most	ADV
aji-66	193	13	advanced	advanced	ADJ
aji-66	193	14	candidate	candidate	NOUN
aji-66	193	15	transmission	transmission	NOUN
aji-66	193	16	-	-	PUNCT
aji-66	193	17	blocking	block	VERB
aji-66	193	18	vaccine	vaccine	NOUN
aji-66	193	19	in	in	ADP
aji-66	193	20	development	development	NOUN
aji-66	193	21	is	be	AUX
aji-66	193	22	a	a	DET
aji-66	193	23	6	6	NUM
aji-66	193	24	histidine	histidine	NOUN
aji-66	193	25	-	-	PUNCT
aji-66	193	26	tagged	tag	VERB
aji-66	193	27	protein	protein	NOUN
aji-66	193	28	tbv25h	tbv25h	NOUN
aji-66	193	29	(	(	PUNCT
aji-66	193	30	transmission	transmission	NOUN
aji-66	193	31	-	-	PUNCT
aji-66	193	32	blocking	block	VERB
aji-66	193	33	vaccine	vaccine	NOUN
aji-66	193	34	based	base	VERB
aji-66	193	35	on	on	ADP
aji-66	193	36	pfs25	pfs25	PROPN
aji-66	193	37	with	with	ADP
aji-66	193	38	a	a	DET
aji-66	193	39	histidine	histidine	ADJ
aji-66	193	40	tag	tag	NOUN
aji-66	193	41	)	)	PUNCT
aji-66	193	42	secreted	secrete	VERB
aji-66	193	43	from	from	ADP
aji-66	193	44	recombinant	recombinant	ADJ
aji-66	193	45	succharomvces	succharomvce	NOUN
aji-66	193	46	cerevisiae	cerevisiae	NOUN
aji-66	193	47	[	[	X
aji-66	193	48	29	29	NUM
aji-66	193	49	]	]	PUNCT
aji-66	193	50	.	.	PUNCT
aji-66	194	1	a	a	DET
aji-66	194	2	modified	modify	VERB
aji-66	194	3	fedbatch	fedbatch	NOUN
aji-66	194	4	fermentation	fermentation	NOUN
aji-66	194	5	protocol	protocol	NOUN
aji-66	194	6	was	be	AUX
aji-66	194	7	developed	develop	VERB
aji-66	194	8	that	that	PRON
aji-66	194	9	optimizes	optimize	VERB
aji-66	194	10	recombinant	recombinant	ADJ
aji-66	194	11	protein	protein	NOUN
aji-66	194	12	production	production	NOUN
aji-66	194	13	using	use	VERB
aji-66	194	14	the	the	DET
aji-66	194	15	simplest	simple	ADJ
aji-66	194	16	and	and	CCONJ
aji-66	194	17	least	least	ADV
aji-66	194	18	expensive	expensive	ADJ
aji-66	194	19	fermentors	fermentor	NOUN
aji-66	194	20	available	available	ADJ
aji-66	194	21	.	.	PUNCT
aji-66	195	1	the	the	DET
aji-66	195	2	6	6	NUM
aji-66	195	3	histidine	histidine	NOUN
aji-66	195	4	-	-	PUNCT
aji-66	195	5	tag	tag	NOUN
aji-66	195	6	is	be	AUX
aji-66	195	7	used	use	VERB
aji-66	195	8	to	to	PART
aji-66	195	9	purify	purify	VERB
aji-66	195	10	the	the	DET
aji-66	195	11	protein	protein	NOUN
aji-66	195	12	with	with	ADP
aji-66	195	13	ease	ease	NOUN
aji-66	195	14	from	from	ADP
aji-66	195	15	the	the	DET
aji-66	195	16	yeast	yeast	NOUN
aji-66	195	17	culture	culture	NOUN
aji-66	195	18	supernatant	supernatant	NOUN
aji-66	195	19	by	by	ADP
aji-66	195	20	affinity	affinity	NOUN
aji-66	195	21	chromatography	chromatography	NOUN
aji-66	195	22	with	with	ADP
aji-66	195	23	nickel	nickel	NOUN
aji-66	195	24	-	-	PUNCT
aji-66	195	25	nta	nta	NOUN
aji-66	195	26	agarose	agarose	NOUN
aji-66	195	27	.	.	PUNCT
aji-66	196	1	the	the	DET
aji-66	196	2	protein	protein	NOUN
aji-66	196	3	is	be	AUX
aji-66	196	4	further	far	ADV
aji-66	196	5	purified	purify	VERB
aji-66	196	6	by	by	ADP
aji-66	196	7	simple	simple	ADJ
aji-66	196	8	gel	gel	NOUN
aji-66	196	9	filtration	filtration	NOUN
aji-66	196	10	chromatography	chromatography	NOUN
aji-66	196	11	and	and	CCONJ
aji-66	196	12	then	then	ADV
aji-66	196	13	adsorbed	adsorb	VERB
aji-66	196	14	to	to	ADP
aji-66	196	15	alum	alum	NOUN
aji-66	196	16	.	.	PUNCT
aji-66	197	1	thus	thus	ADV
aji-66	197	2	,	,	PUNCT
aji-66	197	3	in	in	ADP
aji-66	197	4	keeping	keep	VERB
aji-66	197	5	with	with	ADP
aji-66	197	6	the	the	DET
aji-66	197	7	goal	goal	NOUN
aji-66	197	8	of	of	ADP
aji-66	197	9	technology	technology	NOUN
aji-66	197	10	transfer	transfer	NOUN
aji-66	197	11	to	to	ADP
aji-66	197	12	newly	newly	ADV
aji-66	197	13	industrialized	industrialize	VERB
aji-66	197	14	countries	country	NOUN
aji-66	197	15	,	,	PUNCT
aji-66	197	16	a	a	DET
aji-66	197	17	simple	simple	ADJ
aji-66	197	18	fermentation	fermentation	NOUN
aji-66	197	19	and	and	CCONJ
aji-66	197	20	post	post	ADJ
aji-66	197	21	-	-	ADJ
aji-66	197	22	fermentation	fermentation	NOUN
aji-66	197	23	process	process	NOUN
aji-66	197	24	was	be	AUX
aji-66	197	25	developed	develop	VERB
aji-66	197	26	that	that	PRON
aji-66	197	27	should	should	AUX
aji-66	197	28	allow	allow	VERB
aji-66	197	29	the	the	DET
aji-66	197	30	ultimate	ultimate	ADJ
aji-66	197	31	end	end	NOUN
aji-66	197	32	-	-	PUNCT
aji-66	197	33	users	user	NOUN
aji-66	197	34	to	to	PART
aji-66	197	35	produce	produce	VERB
aji-66	197	36	the	the	DET
aji-66	197	37	vaccine	vaccine	NOUN
aji-66	197	38	themselves	themselves	PRON
aji-66	198	1	[	[	X
aji-66	198	2	30	30	NUM
aji-66	198	3	]	]	PUNCT
aji-66	198	4	.	.	PUNCT
aji-66	199	1	however	however	ADV
aji-66	199	2	,	,	PUNCT
aji-66	199	3	tbv25h	tbv25h	PROPN
aji-66	199	4	/	/	SYM
aji-66	199	5	alum	alum	NOUN
aji-66	199	6	is	be	AUX
aji-66	199	7	not	not	PART
aji-66	199	8	an	an	DET
aji-66	199	9	ideal	ideal	ADJ
aji-66	199	10	transmissionblocking	transmissionblocking	NOUN
aji-66	199	11	vaccine	vaccine	NOUN
aji-66	199	12	for	for	ADP
aji-66	199	13	three	three	NUM
aji-66	199	14	reasons	reason	NOUN
aji-66	199	15	;	;	PUNCT
aji-66	199	16	it	it	PRON
aji-66	199	17	may	may	AUX
aji-66	199	18	require	require	VERB
aji-66	199	19	refrigeration	refrigeration	NOUN
aji-66	199	20	,	,	PUNCT
aji-66	199	21	in	in	ADP
aji-66	199	22	vivo	vivo	ADJ
aji-66	199	23	studies	study	NOUN
aji-66	199	24	have	have	AUX
aji-66	199	25	demonstrated	demonstrate	VERB
aji-66	199	26	that	that	SCONJ
aji-66	199	27	multiple	multiple	ADJ
aji-66	199	28	injections	injection	NOUN
aji-66	199	29	may	may	AUX
aji-66	199	30	be	be	AUX
aji-66	199	31	required	require	VERB
aji-66	199	32	to	to	PART
aji-66	199	33	induce	induce	VERB
aji-66	199	34	the	the	DET
aji-66	199	35	production	production	NOUN
aji-66	199	36	of	of	ADP
aji-66	199	37	transmission	transmission	NOUN
aji-66	199	38	-	-	PUNCT
aji-66	199	39	blocking	block	VERB
aji-66	199	40	antibodies	antibody	NOUN
aji-66	199	41	and	and	CCONJ
aji-66	199	42	immunity	immunity	NOUN
aji-66	199	43	is	be	AUX
aji-66	199	44	relatively	relatively	ADV
aji-66	199	45	short	short	ADV
aji-66	199	46	-	-	PUNCT
aji-66	199	47	lived	live	VERB
aji-66	199	48	.	.	PUNCT
aji-66	200	1	in	in	ADP
aji-66	200	2	its	its	PRON
aji-66	200	3	current	current	ADJ
aji-66	200	4	formulation	formulation	NOUN
aji-66	200	5	,	,	PUNCT
aji-66	200	6	tbv25h	tbv25h	PROPN
aji-66	200	7	will	will	AUX
aji-66	200	8	be	be	AUX
aji-66	200	9	invaluable	invaluable	ADJ
aji-66	200	10	tool	tool	NOUN
aji-66	200	11	for	for	ADP
aji-66	200	12	determining	determine	VERB
aji-66	200	13	the	the	DET
aji-66	200	14	safety	safety	NOUN
aji-66	200	15	of	of	ADP
aji-66	200	16	tbv25h	tbv25h	NOUN
aji-66	200	17	/	/	SYM
aji-66	200	18	alum	alum	NOUN
aji-66	200	19	and	and	CCONJ
aji-66	200	20	help	help	VERB
aji-66	200	21	improve	improve	VERB
aji-66	200	22	our	our	PRON
aji-66	200	23	understanding	understanding	NOUN
aji-66	200	24	on	on	ADP
aji-66	200	25	how	how	SCONJ
aji-66	200	26	antibodies	antibody	NOUN
aji-66	200	27	work	work	VERB
aji-66	200	28	to	to	PART
aji-66	200	29	block	block	VERB
aji-66	200	30	infectivity	infectivity	NOUN
aji-66	200	31	in	in	ADP
aji-66	200	32	vitro	vitro	X
aji-66	200	33	and	and	CCONJ
aji-66	200	34	how	how	SCONJ
aji-66	200	35	it	it	PRON
aji-66	200	36	can	can	AUX
aji-66	200	37	be	be	AUX
aji-66	200	38	elicited	elicit	VERB
aji-66	200	39	in	in	ADP
aji-66	200	40	humans	human	NOUN
aji-66	200	41	.	.	PUNCT
aji-66	201	1	a	a	DET
aji-66	201	2	series	series	NOUN
aji-66	201	3	of	of	ADP
aji-66	201	4	human	human	ADJ
aji-66	201	5	clinical	clinical	ADJ
aji-66	201	6	trials	trial	NOUN
aji-66	201	7	will	will	AUX
aji-66	201	8	be	be	AUX
aji-66	201	9	required	require	VERB
aji-66	201	10	[	[	X
aji-66	201	11	5	5	NUM
aji-66	201	12	]	]	PUNCT
aji-66	201	13	.	.	PUNCT
aji-66	202	1	assessing	assess	VERB
aji-66	202	2	the	the	DET
aji-66	202	3	efficacy	efficacy	NOUN
aji-66	202	4	and	and	CCONJ
aji-66	202	5	the	the	DET
aji-66	202	6	impact	impact	NOUN
aji-66	202	7	of	of	ADP
aji-66	202	8	a	a	DET
aji-66	202	9	tbv	tbv	NOUN
aji-66	202	10	poses	pose	VERB
aji-66	202	11	some	some	DET
aji-66	202	12	unique	unique	ADJ
aji-66	202	13	challenges	challenge	NOUN
aji-66	202	14	[	[	X
aji-66	202	15	11	11	NUM
aji-66	202	16	]	]	PUNCT
aji-66	202	17	.	.	PUNCT
aji-66	203	1	the	the	DET
aji-66	203	2	lack	lack	NOUN
aji-66	203	3	of	of	ADP
aji-66	203	4	reliable	reliable	ADJ
aji-66	203	5	in	in	ADP
aji-66	203	6	vitro	vitro	X
aji-66	203	7	correlates	correlate	NOUN
aji-66	203	8	of	of	ADP
aji-66	203	9	protective	protective	ADJ
aji-66	203	10	efficacy	efficacy	NOUN
aji-66	203	11	has	have	AUX
aji-66	203	12	limited	limit	VERB
aji-66	203	13	the	the	DET
aji-66	203	14	early	early	ADJ
aji-66	203	15	phases	phase	NOUN
aji-66	203	16	of	of	ADP
aji-66	203	17	protective	protective	ADJ
aji-66	203	18	malaria	malaria	NOUN
aji-66	203	19	vaccine	vaccine	NOUN
aji-66	203	20	development	development	NOUN
aji-66	203	21	;	;	PUNCT
aji-66	203	22	the	the	DET
aji-66	203	23	latter	latter	ADJ
aji-66	203	24	field	field	NOUN
aji-66	203	25	-	-	PUNCT
aji-66	203	26	testing	test	VERB
aji-66	203	27	phases	phase	NOUN
aji-66	203	28	of	of	ADP
aji-66	203	29	protective	protective	ADJ
aji-66	203	30	vaccine	vaccine	NOUN
aji-66	203	31	development	development	NOUN
aji-66	203	32	are	be	AUX
aji-66	203	33	straightforward	straightforward	ADJ
aji-66	203	34	.	.	PUNCT
aji-66	204	1	in	in	ADP
aji-66	204	2	contrast	contrast	NOUN
aji-66	204	3	,	,	PUNCT
aji-66	204	4	the	the	DET
aji-66	204	5	early	early	ADJ
aji-66	204	6	phases	phase	NOUN
aji-66	204	7	of	of	ADP
aji-66	204	8	development	development	NOUN
aji-66	204	9	of	of	ADP
aji-66	204	10	a	a	DET
aji-66	204	11	tbv	tbv	NOUN
aji-66	204	12	have	have	VERB
aji-66	204	13	the	the	DET
aji-66	204	14	advantage	advantage	NOUN
aji-66	204	15	of	of	ADP
aji-66	204	16	a	a	DET
aji-66	204	17	reliable	reliable	ADJ
aji-66	204	18	(	(	PUNCT
aji-66	204	19	but	but	CCONJ
aji-66	204	20	tedious	tedious	ADJ
aji-66	204	21	)	)	PUNCT
aji-66	204	22	in	in	ADP
aji-66	204	23	vitro	vitro	X
aji-66	204	24	assay	assay	VERB
aji-66	204	25	for	for	ADP
aji-66	204	26	assessing	assess	VERB
aji-66	204	27	transmission	transmission	NOUN
aji-66	204	28	-	-	PUNCT
aji-66	204	29	blocking	block	VERB
aji-66	204	30	activity	activity	NOUN
aji-66	204	31	,	,	PUNCT
aji-66	204	32	the	the	DET
aji-66	204	33	membrane	membrane	NOUN
aji-66	204	34	feeding	feeding	NOUN
aji-66	204	35	assay	assay	NOUN
aji-66	204	36	in	in	ADP
aji-66	204	37	which	which	PRON
aji-66	204	38	in	in	ADP
aji-66	204	39	vitro	vitro	X
aji-66	204	40	cultured	cultured	ADJ
aji-66	204	41	gametocytes	gametocyte	NOUN
aji-66	204	42	are	be	AUX
aji-66	204	43	mixed	mix	VERB
aji-66	204	44	with	with	ADP
aji-66	204	45	test	test	NOUN
aji-66	204	46	serum	serum	NOUN
aji-66	204	47	and	and	CCONJ
aji-66	204	48	fed	feed	VERB
aji-66	204	49	through	through	ADP
aji-66	204	50	an	an	DET
aji-66	204	51	artificial	artificial	ADJ
aji-66	204	52	membrane	membrane	NOUN
aji-66	204	53	to	to	ADP
aji-66	204	54	starved	starve	VERB
aji-66	204	55	mosquitoes	mosquito	NOUN
aji-66	204	56	.	.	PUNCT
aji-66	205	1	the	the	DET
aji-66	205	2	degree	degree	NOUN
aji-66	205	3	to	to	PART
aji-66	205	4	which	which	PRON
aji-66	205	5	the	the	DET
aji-66	205	6	test	test	NOUN
aji-66	205	7	serum	serum	NOUN
aji-66	205	8	inhibits	inhibit	VERB
aji-66	205	9	infectivity	infectivity	NOUN
aji-66	205	10	is	be	AUX
aji-66	205	11	determined	determine	VERB
aji-66	205	12	1	1	NUM
aji-66	205	13	week	week	NOUN
aji-66	205	14	after	after	ADP
aji-66	205	15	an	an	DET
aji-66	205	16	infectious	infectious	ADJ
aji-66	205	17	blood	blood	NOUN
aji-66	205	18	meal	meal	NOUN
aji-66	205	19	by	by	ADP
aji-66	205	20	scoring	score	VERB
aji-66	205	21	mercurochromestained	mercurochromestaine	VERB
aji-66	205	22	mosquito	mosquito	ADJ
aji-66	205	23	midguts	midgut	NOUN
aji-66	205	24	for	for	ADP
aji-66	205	25	oocysts	oocyst	NOUN
aji-66	205	26	[	[	X
aji-66	205	27	31	31	NUM
aji-66	205	28	]	]	PUNCT
aji-66	205	29	.	.	PUNCT
aji-66	206	1	nevertheless	nevertheless	ADV
aji-66	206	2	,	,	PUNCT
aji-66	206	3	in	in	ADP
aji-66	206	4	vivo	vivo	ADJ
aji-66	206	5	efficacy	efficacy	NOUN
aji-66	206	6	for	for	ADP
aji-66	206	7	transmissionblocking	transmissionblocke	VERB
aji-66	206	8	vaccines	vaccine	NOUN
aji-66	206	9	will	will	AUX
aji-66	206	10	require	require	VERB
aji-66	206	11	labour	labour	ADJ
aji-66	206	12	-	-	PUNCT
aji-66	206	13	intensive	intensive	ADJ
aji-66	206	14	,	,	PUNCT
aji-66	206	15	expensive	expensive	ADJ
aji-66	206	16	field	field	NOUN
aji-66	206	17	testing	testing	NOUN
aji-66	206	18	[	[	X
aji-66	206	19	21	21	NUM
aji-66	206	20	]	]	PUNCT
aji-66	206	21	.	.	PUNCT
aji-66	207	1	wangai	wangai	INTJ
aji-66	207	2	et	et	PROPN
aji-66	207	3	al	al	PROPN
aji-66	207	4	.	.	PROPN
aji-66	207	5	;	;	PUNCT
aji-66	207	6	aji	aji	PROPN
aji-66	207	7	,	,	PUNCT
aji-66	207	8	4(1	4(1	NOUN
aji-66	207	9	):	):	PUNCT
aji-66	207	10	77	77	NUM
aji-66	207	11	-	-	SYM
aji-66	207	12	84	84	NUM
aji-66	207	13	,	,	PUNCT
aji-66	207	14	2021	2021	NUM
aji-66	207	15	;	;	PUNCT
aji-66	207	16	article	article	NOUN
aji-66	207	17	no.aji.69854	no.aji.69854	NOUN
aji-66	207	18	81	81	NUM
aji-66	207	19	the	the	DET
aji-66	207	20	assessment	assessment	NOUN
aji-66	207	21	of	of	ADP
aji-66	207	22	the	the	DET
aji-66	207	23	actual	actual	ADJ
aji-66	207	24	efficacy	efficacy	NOUN
aji-66	207	25	of	of	ADP
aji-66	207	26	a	a	DET
aji-66	207	27	tbv	tbv	PROPN
aji-66	207	28	requires	require	VERB
aji-66	207	29	field	field	NOUN
aji-66	207	30	testing	testing	NOUN
aji-66	207	31	unlike	unlike	ADP
aji-66	207	32	any	any	DET
aji-66	207	33	vaccine	vaccine	NOUN
aji-66	207	34	tested	test	VERB
aji-66	207	35	to	to	ADP
aji-66	207	36	date	date	NOUN
aji-66	207	37	,	,	PUNCT
aji-66	207	38	malaria	malaria	NOUN
aji-66	207	39	or	or	CCONJ
aji-66	207	40	otherwise	otherwise	ADV
aji-66	207	41	.	.	PUNCT
aji-66	208	1	although	although	SCONJ
aji-66	208	2	a	a	DET
aji-66	208	3	phase	phase	NOUN
aji-66	208	4	i	i	PRON
aji-66	208	5	trial	trial	NOUN
aji-66	208	6	designed	design	VERB
aji-66	208	7	to	to	PART
aji-66	208	8	establish	establish	VERB
aji-66	208	9	safety	safety	NOUN
aji-66	208	10	and	and	CCONJ
aji-66	208	11	immunogenicity	immunogenicity	NOUN
aji-66	208	12	has	have	AUX
aji-66	208	13	been	be	AUX
aji-66	208	14	used	use	VERB
aji-66	208	15	to	to	PART
aji-66	208	16	assess	assess	VERB
aji-66	208	17	efficacy	efficacy	NOUN
aji-66	208	18	in	in	ADP
aji-66	208	19	vitro	vitro	X
aji-66	208	20	(	(	PUNCT
aji-66	208	21	using	use	VERB
aji-66	208	22	the	the	DET
aji-66	208	23	membrane	membrane	NOUN
aji-66	208	24	feeding	feeding	NOUN
aji-66	208	25	assay	assay	NOUN
aji-66	208	26	)	)	PUNCT
aji-66	208	27	and	and	CCONJ
aji-66	208	28	a	a	DET
aji-66	208	29	phase	phase	NOUN
aji-66	208	30	iib	iib	NOUN
aji-66	208	31	(	(	PUNCT
aji-66	208	32	naturally	naturally	ADV
aji-66	208	33	acquired	acquire	VERB
aji-66	208	34	parasite	parasite	NOUN
aji-66	208	35	infection	infection	NOUN
aji-66	208	36	rather	rather	ADV
aji-66	208	37	than	than	ADP
aji-66	208	38	experimental	experimental	ADJ
aji-66	208	39	parasite	parasite	NOUN
aji-66	208	40	challenge	challenge	NOUN
aji-66	208	41	)	)	PUNCT
aji-66	208	42	can	can	AUX
aji-66	208	43	be	be	AUX
aji-66	208	44	used	use	VERB
aji-66	208	45	to	to	PART
aji-66	208	46	assess	assess	VERB
aji-66	208	47	in	in	ADP
aji-66	208	48	vivo	vivo	ADJ
aji-66	208	49	efficacy	efficacy	NOUN
aji-66	208	50	by	by	ADP
aji-66	208	51	feeding	feed	VERB
aji-66	208	52	laboratory	laboratory	NOUN
aji-66	208	53	-	-	PUNCT
aji-66	208	54	reared	rear	VERB
aji-66	208	55	mosquitoes	mosquito	NOUN
aji-66	208	56	directly	directly	ADV
aji-66	208	57	on	on	ADP
aji-66	208	58	infected	infected	ADJ
aji-66	208	59	volunteers	volunteer	NOUN
aji-66	208	60	,	,	PUNCT
aji-66	208	61	designing	design	VERB
aji-66	208	62	and	and	CCONJ
aji-66	208	63	executing	execute	VERB
aji-66	208	64	robust	robust	ADJ
aji-66	208	65	phase	phase	NOUN
aji-66	208	66	iii	iii	NUM
aji-66	208	67	trials	trial	NOUN
aji-66	208	68	(	(	PUNCT
aji-66	208	69	i.e.	i.e.	X
aji-66	208	70	testing	testing	NOUN
aji-66	208	71	efficacy	efficacy	NOUN
aji-66	208	72	in	in	ADP
aji-66	208	73	the	the	DET
aji-66	208	74	field	field	NOUN
aji-66	208	75	)	)	PUNCT
aji-66	208	76	that	that	PRON
aji-66	208	77	determines	determine	VERB
aji-66	208	78	the	the	DET
aji-66	208	79	impact	impact	NOUN
aji-66	208	80	of	of	ADP
aji-66	208	81	the	the	DET
aji-66	208	82	vaccine	vaccine	NOUN
aji-66	208	83	on	on	ADP
aji-66	208	84	natural	natural	ADJ
aji-66	208	85	transmission	transmission	NOUN
aji-66	208	86	and	and	CCONJ
aji-66	208	87	on	on	ADP
aji-66	208	88	preventing	prevent	VERB
aji-66	208	89	morbidity	morbidity	NOUN
aji-66	208	90	and	and	CCONJ
aji-66	208	91	mortality	mortality	NOUN
aji-66	208	92	is	be	AUX
aji-66	208	93	difficult	difficult	ADJ
aji-66	208	94	[	[	X
aji-66	208	95	8	8	NUM
aji-66	208	96	]	]	PUNCT
aji-66	208	97	.	.	PUNCT
aji-66	209	1	this	this	PRON
aji-66	209	2	is	be	AUX
aji-66	209	3	because	because	SCONJ
aji-66	209	4	,	,	PUNCT
aji-66	209	5	in	in	ADP
aji-66	209	6	phase	phase	NOUN
aji-66	209	7	iii	iii	NUM
aji-66	209	8	trials	trial	NOUN
aji-66	209	9	,	,	PUNCT
aji-66	209	10	the	the	DET
aji-66	209	11	statistical	statistical	ADJ
aji-66	209	12	or	or	CCONJ
aji-66	209	13	study	study	NOUN
aji-66	209	14	unit	unit	NOUN
aji-66	209	15	is	be	AUX
aji-66	209	16	not	not	PART
aji-66	209	17	individual	individual	NOUN
aji-66	209	18	-	-	PUNCT
aji-66	209	19	based	base	VERB
aji-66	209	20	but	but	CCONJ
aji-66	209	21	requires	require	VERB
aji-66	209	22	a	a	DET
aji-66	209	23	well	well	ADV
aji-66	209	24	-	-	PUNCT
aji-66	209	25	defined	define	VERB
aji-66	209	26	and	and	CCONJ
aji-66	209	27	,	,	PUNCT
aji-66	209	28	at	at	ADP
aji-66	209	29	least	least	ADJ
aji-66	209	30	partially	partially	ADV
aji-66	209	31	,	,	PUNCT
aji-66	209	32	isolated	isolated	ADJ
aji-66	209	33	population	population	NOUN
aji-66	209	34	of	of	ADP
aji-66	209	35	sufficient	sufficient	ADJ
aji-66	209	36	size	size	NOUN
aji-66	209	37	in	in	ADP
aji-66	209	38	a	a	DET
aji-66	209	39	malaria	malaria	NOUN
aji-66	209	40	-	-	PUNCT
aji-66	209	41	endemic	endemic	ADJ
aji-66	209	42	or	or	CCONJ
aji-66	209	43	seasonal	seasonal	ADJ
aji-66	209	44	malaria	malaria	NOUN
aji-66	209	45	area	area	NOUN
aji-66	209	46	.	.	PUNCT
aji-66	210	1	the	the	DET
aji-66	210	2	setting	setting	NOUN
aji-66	210	3	must	must	AUX
aji-66	210	4	be	be	AUX
aji-66	210	5	such	such	ADJ
aji-66	210	6	that	that	SCONJ
aji-66	210	7	the	the	DET
aji-66	210	8	rate	rate	NOUN
aji-66	210	9	of	of	ADP
aji-66	210	10	transmission	transmission	NOUN
aji-66	210	11	is	be	AUX
aji-66	210	12	not	not	PART
aji-66	210	13	so	so	ADV
aji-66	210	14	high	high	ADJ
aji-66	210	15	that	that	SCONJ
aji-66	210	16	a	a	DET
aji-66	210	17	possible	possible	ADJ
aji-66	210	18	positive	positive	ADJ
aji-66	210	19	effect	effect	NOUN
aji-66	210	20	is	be	AUX
aji-66	210	21	missed	miss	VERB
aji-66	210	22	,	,	PUNCT
aji-66	210	23	but	but	CCONJ
aji-66	210	24	not	not	PART
aji-66	210	25	so	so	ADV
aji-66	210	26	low	low	ADJ
aji-66	210	27	that	that	SCONJ
aji-66	210	28	the	the	DET
aji-66	210	29	observed	observed	ADJ
aji-66	210	30	effect	effect	NOUN
aji-66	210	31	would	would	AUX
aji-66	210	32	have	have	VERB
aji-66	210	33	little	little	ADJ
aji-66	210	34	consequence	consequence	NOUN
aji-66	210	35	as	as	ADP
aji-66	210	36	a	a	DET
aji-66	210	37	public	public	ADJ
aji-66	210	38	health	health	NOUN
aji-66	210	39	measure	measure	NOUN
aji-66	210	40	.	.	PUNCT
aji-66	211	1	the	the	DET
aji-66	211	2	control	control	NOUN
aji-66	211	3	and	and	CCONJ
aji-66	211	4	test	test	NOUN
aji-66	211	5	study	study	NOUN
aji-66	211	6	units	unit	NOUN
aji-66	211	7	,	,	PUNCT
aji-66	211	8	or	or	CCONJ
aji-66	211	9	communities	community	NOUN
aji-66	211	10	,	,	PUNCT
aji-66	211	11	must	must	AUX
aji-66	211	12	have	have	VERB
aji-66	211	13	little	little	ADJ
aji-66	211	14	interchange	interchange	NOUN
aji-66	211	15	between	between	ADP
aji-66	211	16	vaccinated	vaccinated	ADJ
aji-66	211	17	and	and	CCONJ
aji-66	211	18	unvaccinated	unvaccinated	ADJ
aji-66	211	19	populations	population	NOUN
aji-66	211	20	but	but	CCONJ
aji-66	211	21	must	must	AUX
aji-66	211	22	be	be	AUX
aji-66	211	23	similar	similar	ADJ
aji-66	211	24	to	to	PART
aji-66	211	25	allow	allow	VERB
aji-66	211	26	comparative	comparative	ADJ
aji-66	211	27	analyses	analysis	NOUN
aji-66	211	28	between	between	ADP
aji-66	211	29	among	among	ADP
aji-66	211	30	sites	site	NOUN
aji-66	211	31	[	[	X
aji-66	211	32	22	22	NUM
aji-66	211	33	]	]	PUNCT
aji-66	211	34	.	.	PUNCT
aji-66	212	1	depending	depend	VERB
aji-66	212	2	on	on	ADP
aji-66	212	3	the	the	DET
aji-66	212	4	rate	rate	NOUN
aji-66	212	5	of	of	ADP
aji-66	212	6	transmission	transmission	NOUN
aji-66	212	7	,	,	PUNCT
aji-66	212	8	the	the	DET
aji-66	212	9	endpoints	endpoint	NOUN
aji-66	212	10	that	that	PRON
aji-66	212	11	are	be	AUX
aji-66	212	12	chosen	choose	VERB
aji-66	212	13	,	,	PUNCT
aji-66	212	14	the	the	DET
aji-66	212	15	similarity	similarity	NOUN
aji-66	212	16	in	in	ADP
aji-66	212	17	malaria	malaria	NOUN
aji-66	212	18	transmission	transmission	NOUN
aji-66	212	19	and	and	CCONJ
aji-66	212	20	endemicity	endemicity	NOUN
aji-66	212	21	,	,	PUNCT
aji-66	212	22	the	the	DET
aji-66	212	23	existence	existence	NOUN
aji-66	212	24	of	of	ADP
aji-66	212	25	a	a	DET
aji-66	212	26	malaria	malaria	NOUN
aji-66	212	27	transmission	transmission	NOUN
aji-66	212	28	control	control	NOUN
aji-66	212	29	programme	programme	NOUN
aji-66	212	30	(	(	PUNCT
aji-66	212	31	e.g.	e.g.	ADV
aji-66	212	32	,	,	PUNCT
aji-66	212	33	the	the	DET
aji-66	212	34	presence	presence	NOUN
aji-66	212	35	of	of	ADP
aji-66	212	36	p.	p.	NOUN
aji-66	212	37	vivax	vivax	PROPN
aji-66	212	38	transmission	transmission	NOUN
aji-66	212	39	)	)	PUNCT
aji-66	212	40	,	,	PUNCT
aji-66	212	41	and	and	CCONJ
aji-66	212	42	the	the	DET
aji-66	212	43	cooperation	cooperation	NOUN
aji-66	212	44	of	of	ADP
aji-66	212	45	all	all	DET
aji-66	212	46	individuals	individual	NOUN
aji-66	212	47	in	in	ADP
aji-66	212	48	each	each	DET
aji-66	212	49	community	community	NOUN
aji-66	212	50	,	,	PUNCT
aji-66	212	51	as	as	ADV
aji-66	212	52	few	few	ADJ
aji-66	212	53	as	as	ADP
aji-66	212	54	one	one	NUM
aji-66	212	55	or	or	CCONJ
aji-66	212	56	two	two	NUM
aji-66	212	57	test	test	NOUN
aji-66	212	58	villages	village	NOUN
aji-66	212	59	and	and	CCONJ
aji-66	212	60	an	an	DET
aji-66	212	61	equal	equal	ADJ
aji-66	212	62	or	or	CCONJ
aji-66	212	63	greater	great	ADJ
aji-66	212	64	number	number	NOUN
aji-66	212	65	of	of	ADP
aji-66	212	66	control	control	NOUN
aji-66	212	67	villages	village	NOUN
aji-66	212	68	may	may	AUX
aji-66	212	69	be	be	AUX
aji-66	212	70	all	all	PRON
aji-66	212	71	that	that	PRON
aji-66	212	72	is	be	AUX
aji-66	212	73	necessary	necessary	ADJ
aji-66	212	74	to	to	PART
aji-66	212	75	preliminarily	preliminarily	ADV
aji-66	212	76	evaluate	evaluate	VERB
aji-66	212	77	efficacy	efficacy	NOUN
aji-66	212	78	[	[	X
aji-66	212	79	28	28	NUM
aji-66	212	80	]	]	PUNCT
aji-66	212	81	.	.	PUNCT
aji-66	213	1	several	several	ADJ
aji-66	213	2	ethical	ethical	ADJ
aji-66	213	3	issues	issue	NOUN
aji-66	213	4	,	,	PUNCT
aji-66	213	5	however	however	ADV
aji-66	213	6	,	,	PUNCT
aji-66	213	7	must	must	AUX
aji-66	213	8	be	be	AUX
aji-66	213	9	adequately	adequately	ADV
aji-66	213	10	addressed	address	VERB
aji-66	213	11	before	before	ADP
aji-66	213	12	undertaking	undertake	VERB
aji-66	213	13	these	these	DET
aji-66	213	14	human	human	ADJ
aji-66	213	15	clinical	clinical	ADJ
aji-66	213	16	trials	trial	NOUN
aji-66	213	17	.	.	PUNCT
aji-66	214	1	despite	despite	SCONJ
aji-66	214	2	the	the	DET
aji-66	214	3	enormity	enormity	NOUN
aji-66	214	4	of	of	ADP
aji-66	214	5	the	the	DET
aji-66	214	6	health	health	NOUN
aji-66	214	7	problems	problem	NOUN
aji-66	214	8	that	that	PRON
aji-66	214	9	malaria	malaria	NOUN
aji-66	214	10	poses	pose	VERB
aji-66	214	11	worldwide	worldwide	ADV
aji-66	214	12	.	.	PUNCT
aji-66	215	1	an	an	DET
aji-66	215	2	effective	effective	ADJ
aji-66	215	3	malaria	malaria	NOUN
aji-66	215	4	vaccine	vaccine	NOUN
aji-66	215	5	has	have	AUX
aji-66	215	6	eluded	elude	VERB
aji-66	215	7	us	we	PRON
aji-66	215	8	.	.	PUNCT
aji-66	216	1	lack	lack	NOUN
aji-66	216	2	of	of	ADP
aji-66	216	3	understanding	understanding	NOUN
aji-66	216	4	as	as	ADP
aji-66	216	5	to	to	ADP
aji-66	216	6	what	what	PRON
aji-66	216	7	the	the	DET
aji-66	216	8	mechanism	mechanism	NOUN
aji-66	216	9	of	of	ADP
aji-66	216	10	protective	protective	ADJ
aji-66	216	11	immunity	immunity	NOUN
aji-66	216	12	is	be	AUX
aji-66	216	13	,	,	PUNCT
aji-66	216	14	limited	limited	ADJ
aji-66	216	15	research	research	NOUN
aji-66	216	16	funding	funding	NOUN
aji-66	216	17	,	,	PUNCT
aji-66	216	18	and	and	CCONJ
aji-66	216	19	perhaps	perhaps	ADV
aji-66	216	20	lack	lack	NOUN
aji-66	216	21	of	of	ADP
aji-66	216	22	the	the	DET
aji-66	216	23	appropriate	appropriate	ADJ
aji-66	216	24	technologies	technology	NOUN
aji-66	216	25	necessary	necessary	ADJ
aji-66	216	26	to	to	PART
aji-66	216	27	develop	develop	VERB
aji-66	216	28	an	an	DET
aji-66	216	29	effective	effective	ADJ
aji-66	216	30	vaccine	vaccine	NOUN
aji-66	216	31	has	have	AUX
aji-66	216	32	probably	probably	ADV
aji-66	216	33	contributed	contribute	VERB
aji-66	216	34	to	to	ADP
aji-66	216	35	the	the	DET
aji-66	216	36	delayed	delay	VERB
aji-66	216	37	development	development	NOUN
aji-66	216	38	of	of	ADP
aji-66	216	39	effective	effective	ADJ
aji-66	216	40	malaria	malaria	NOUN
aji-66	216	41	vaccines	vaccine	NOUN
aji-66	216	42	.	.	PUNCT
aji-66	217	1	novel	novel	ADJ
aji-66	217	2	approaches	approach	NOUN
aji-66	217	3	and	and	CCONJ
aji-66	217	4	technologies	technology	NOUN
aji-66	217	5	may	may	AUX
aji-66	217	6	be	be	AUX
aji-66	217	7	required	require	VERB
aji-66	217	8	such	such	ADJ
aji-66	217	9	as	as	ADP
aji-66	217	10	tbvs	tbvs	PROPN
aji-66	217	11	.	.	PROPN
aji-66	218	1	4.1	4.1	NUM
aji-66	218	2	sequence	sequence	NOUN
aji-66	218	3	polymorphisms	polymorphism	NOUN
aji-66	218	4	of	of	ADP
aji-66	218	5	vaccine	vaccine	NOUN
aji-66	218	6	candidates	candidate	NOUN
aji-66	218	7	considering	consider	VERB
aji-66	218	8	that	that	SCONJ
aji-66	218	9	amino	amino	NOUN
aji-66	218	10	acid	acid	NOUN
aji-66	218	11	sequence	sequence	NOUN
aji-66	218	12	polymorphisms	polymorphism	NOUN
aji-66	218	13	present	present	VERB
aji-66	218	14	a	a	DET
aji-66	218	15	plausible	plausible	ADJ
aji-66	218	16	bottleneck	bottleneck	NOUN
aji-66	218	17	for	for	ADP
aji-66	218	18	malaria	malaria	NOUN
aji-66	218	19	subunit	subunit	NOUN
aji-66	218	20	vaccine	vaccine	NOUN
aji-66	218	21	development	development	NOUN
aji-66	218	22	[	[	X
aji-66	218	23	32	32	NUM
aji-66	218	24	]	]	PUNCT
aji-66	218	25	,	,	PUNCT
aji-66	218	26	there	there	PRON
aji-66	218	27	is	be	VERB
aji-66	218	28	a	a	DET
aji-66	218	29	major	major	ADJ
aji-66	218	30	concern	concern	NOUN
aji-66	218	31	that	that	SCONJ
aji-66	218	32	b	b	X
aji-66	218	33	-	-	PUNCT
aji-66	218	34	cell	cell	NOUN
aji-66	218	35	epitopes	epitope	NOUN
aji-66	218	36	targeted	target	VERB
aji-66	218	37	by	by	ADP
aji-66	218	38	transmission	transmission	NOUN
aji-66	218	39	antibodies	antibody	NOUN
aji-66	218	40	might	might	AUX
aji-66	218	41	be	be	AUX
aji-66	218	42	highly	highly	ADV
aji-66	218	43	variable	variable	ADJ
aji-66	218	44	[	[	X
aji-66	218	45	13	13	NUM
aji-66	218	46	]	]	PUNCT
aji-66	218	47	.	.	PUNCT
aji-66	219	1	to	to	PART
aji-66	219	2	assess	assess	VERB
aji-66	219	3	whether	whether	SCONJ
aji-66	219	4	any	any	PRON
aji-66	219	5	of	of	ADP
aji-66	219	6	the	the	DET
aji-66	219	7	polymorphisms	polymorphism	NOUN
aji-66	219	8	affect	affect	VERB
aji-66	219	9	the	the	DET
aji-66	219	10	antibody	antibody	NOUN
aji-66	219	11	affinity	affinity	NOUN
aji-66	219	12	towards	towards	ADP
aji-66	219	13	pfs48/45	pfs48/45	NOUN
aji-66	219	14	,	,	PUNCT
aji-66	219	15	serum	serum	NOUN
aji-66	219	16	samples	sample	NOUN
aji-66	219	17	from	from	ADP
aji-66	219	18	rats	rat	NOUN
aji-66	219	19	immunized	immunize	VERB
aji-66	219	20	with	with	ADP
aji-66	219	21	r0.10c	r0.10c	NOUN
aji-66	219	22	were	be	AUX
aji-66	219	23	tested	test	VERB
aji-66	219	24	in	in	ADP
aji-66	219	25	the	the	DET
aji-66	219	26	smfa	smfa	NOUN
aji-66	219	27	with	with	ADP
aji-66	219	28	three	three	NUM
aji-66	219	29	distinct	distinct	ADJ
aji-66	219	30	p.	p.	NOUN
aji-66	219	31	falciparum	falciparum	ADJ
aji-66	219	32	isolates	isolate	NOUN
aji-66	219	33	of	of	ADP
aji-66	219	34	asian	asian	ADJ
aji-66	219	35	and	and	CCONJ
aji-66	219	36	african	african	ADJ
aji-66	219	37	origin	origin	NOUN
aji-66	219	38	,	,	PUNCT
aji-66	219	39	i.e.	i.e.	X
aji-66	219	40	nf54	nf54	PROPN
aji-66	219	41	,	,	PUNCT
aji-66	219	42	nf166	nf166	PROPN
aji-66	219	43	and	and	CCONJ
aji-66	219	44	nf135	nf135	NOUN
aji-66	220	1	[	[	X
aji-66	220	2	33	33	NUM
aji-66	220	3	]	]	PUNCT
aji-66	220	4	.	.	PUNCT
aji-66	221	1	taken	take	VERB
aji-66	221	2	together	together	ADV
aji-66	221	3	,	,	PUNCT
aji-66	221	4	available	available	ADJ
aji-66	221	5	data	datum	NOUN
aji-66	221	6	from	from	ADP
aji-66	221	7	sequencing	sequence	VERB
aji-66	221	8	and	and	CCONJ
aji-66	221	9	antibody	antibody	NOUN
aji-66	221	10	binding	bind	VERB
aji-66	221	11	studies	study	NOUN
aji-66	221	12	of	of	ADP
aji-66	221	13	field	field	NOUN
aji-66	221	14	isolates	isolate	NOUN
aji-66	221	15	suggest	suggest	VERB
aji-66	221	16	that	that	SCONJ
aji-66	221	17	parasite	parasite	NOUN
aji-66	221	18	diversity	diversity	NOUN
aji-66	221	19	is	be	AUX
aji-66	221	20	unlikely	unlikely	ADJ
aji-66	221	21	to	to	PART
aji-66	221	22	become	become	VERB
aji-66	221	23	an	an	DET
aji-66	221	24	obstacle	obstacle	NOUN
aji-66	221	25	for	for	ADP
aji-66	221	26	the	the	DET
aji-66	221	27	clinical	clinical	ADJ
aji-66	221	28	development	development	NOUN
aji-66	221	29	of	of	ADP
aji-66	221	30	pfs48/45	pfs48/45	NOUN
aji-66	221	31	-	-	PUNCT
aji-66	221	32	based	base	VERB
aji-66	221	33	vaccines	vaccine	NOUN
aji-66	221	34	[	[	X
aji-66	221	35	13	13	NUM
aji-66	221	36	]	]	PUNCT
aji-66	221	37	.	.	PUNCT
aji-66	222	1	expression	expression	NOUN
aji-66	222	2	of	of	ADP
aji-66	222	3	a	a	DET
aji-66	222	4	recombinant	recombinant	ADJ
aji-66	222	5	vaccine	vaccine	NOUN
aji-66	222	6	has	have	AUX
aji-66	222	7	been	be	AUX
aji-66	222	8	hindered	hinder	VERB
aji-66	222	9	by	by	ADP
aji-66	222	10	the	the	DET
aji-66	222	11	inability	inability	NOUN
aji-66	222	12	to	to	PART
aji-66	222	13	produce	produce	VERB
aji-66	222	14	sufficiently	sufficiently	ADV
aji-66	222	15	high	high	ADJ
aji-66	222	16	yield	yield	NOUN
aji-66	222	17	recombinant	recombinant	ADJ
aji-66	222	18	proteins	protein	NOUN
aji-66	222	19	that	that	PRON
aji-66	222	20	refolds	refold	VERB
aji-66	222	21	into	into	ADP
aji-66	222	22	the	the	DET
aji-66	222	23	native	native	ADJ
aji-66	222	24	structure	structure	NOUN
aji-66	222	25	required	require	VERB
aji-66	222	26	for	for	ADP
aji-66	222	27	the	the	DET
aji-66	222	28	induction	induction	NOUN
aji-66	222	29	of	of	ADP
aji-66	222	30	tbv	tbv	DET
aji-66	222	31	antibody	antibody	NOUN
aji-66	222	32	production	production	NOUN
aji-66	222	33	[	[	X
aji-66	222	34	34	34	NUM
aji-66	222	35	]	]	PUNCT
aji-66	222	36	.	.	PUNCT
aji-66	223	1	proper	proper	ADJ
aji-66	223	2	folding	folding	NOUN
aji-66	223	3	of	of	ADP
aji-66	223	4	many	many	ADJ
aji-66	223	5	cysteine	cysteine	ADJ
aji-66	223	6	-	-	PUNCT
aji-66	223	7	rich	rich	ADJ
aji-66	223	8	proteins	protein	NOUN
aji-66	223	9	,	,	PUNCT
aji-66	223	10	including	include	VERB
aji-66	223	11	pfs48/45	pfs48/45	NOUN
aji-66	223	12	,	,	PUNCT
aji-66	223	13	depends	depend	VERB
aji-66	223	14	on	on	ADP
aji-66	223	15	the	the	DET
aji-66	223	16	correct	correct	ADJ
aji-66	223	17	formation	formation	NOUN
aji-66	223	18	of	of	ADP
aji-66	223	19	disulphide	disulphide	ADJ
aji-66	223	20	bridges	bridge	NOUN
aji-66	223	21	[	[	X
aji-66	223	22	35	35	NUM
aji-66	223	23	]	]	PUNCT
aji-66	223	24	.	.	PUNCT
aji-66	224	1	in	in	ADP
aji-66	224	2	eukaryotes	eukaryote	NOUN
aji-66	224	3	,	,	PUNCT
aji-66	224	4	the	the	DET
aji-66	224	5	oxidizing	oxidize	VERB
aji-66	224	6	environment	environment	NOUN
aji-66	224	7	of	of	ADP
aji-66	224	8	the	the	DET
aji-66	224	9	endoplasmic	endoplasmic	ADJ
aji-66	224	10	reticulum	reticulum	NOUN
aji-66	224	11	(	(	PUNCT
aji-66	224	12	er	er	INTJ
aji-66	224	13	)	)	PUNCT
aji-66	224	14	provides	provide	VERB
aji-66	224	15	a	a	DET
aji-66	224	16	milieu	milieu	NOUN
aji-66	224	17	for	for	ADP
aji-66	224	18	disulphide	disulphide	ADJ
aji-66	224	19	bonds	bond	NOUN
aji-66	224	20	formation	formation	NOUN
aji-66	224	21	,	,	PUNCT
aji-66	224	22	a	a	DET
aji-66	224	23	process	process	NOUN
aji-66	224	24	that	that	PRON
aji-66	224	25	is	be	AUX
aji-66	224	26	mediated	mediate	VERB
aji-66	224	27	by	by	ADP
aji-66	224	28	er	er	INTJ
aji-66	224	29	oxidoreductase	oxidoreductase	NOUN
aji-66	224	30	1	1	NUM
aji-66	224	31	(	(	PUNCT
aji-66	224	32	ero1	ero1	PROPN
aji-66	224	33	)	)	PUNCT
aji-66	224	34	and	and	CCONJ
aji-66	224	35	protein	protein	NOUN
aji-66	224	36	disulfide	disulfide	NOUN
aji-66	224	37	isomerase	isomerase	NOUN
aji-66	224	38	(	(	PUNCT
aji-66	224	39	pdi	pdi	PROPN
aji-66	224	40	)	)	PUNCT
aji-66	225	1	[	[	X
aji-66	225	2	36	36	NUM
aji-66	225	3	]	]	PUNCT
aji-66	225	4	.	.	PUNCT
aji-66	226	1	p.	p.	NOUN
aji-66	226	2	falciparum	falciparum	PROPN
aji-66	226	3	possesses	possess	VERB
aji-66	226	4	four	four	NUM
aji-66	226	5	protein	protein	NOUN
aji-66	226	6	disulfide	disulfide	NOUN
aji-66	226	7	isomerases	isomerase	NOUN
aji-66	226	8	(	(	PUNCT
aji-66	226	9	pfpdis	pfpdis	NOUN
aji-66	226	10	)	)	PUNCT
aji-66	226	11	of	of	ADP
aji-66	226	12	which	which	PRON
aji-66	226	13	,	,	PUNCT
aji-66	226	14	pfpdi-8	pfpdi-8	PROPN
aji-66	226	15	and	and	CCONJ
aji-66	226	16	pfpdi-11	pfpdi-11	PROPN
aji-66	226	17	have	have	AUX
aji-66	226	18	been	be	AUX
aji-66	226	19	expressed	express	VERB
aji-66	226	20	in	in	ADP
aji-66	226	21	gametocytes	gametocyte	NOUN
aji-66	227	1	[	[	X
aji-66	227	2	37	37	NUM
aji-66	227	3	]	]	PUNCT
aji-66	227	4	.	.	PUNCT
aji-66	228	1	pfs48/45	pfs48/45	PROPN
aji-66	228	2	and	and	CCONJ
aji-66	228	3	pfs25	pfs25	PROPN
aji-66	228	4	have	have	AUX
aji-66	228	5	been	be	AUX
aji-66	228	6	expressed	express	VERB
aji-66	228	7	in	in	ADP
aji-66	228	8	different	different	ADJ
aji-66	228	9	eukaryotic	eukaryotic	ADJ
aji-66	228	10	expression	expression	NOUN
aji-66	228	11	systems	system	NOUN
aji-66	228	12	possessing	possess	VERB
aji-66	228	13	ero1	ero1	NOUN
aji-66	228	14	and	and	CCONJ
aji-66	228	15	pdi	pdi	NOUN
aji-66	228	16	analogous	analogous	ADJ
aji-66	228	17	but	but	CCONJ
aji-66	228	18	some	some	DET
aji-66	228	19	systems	system	NOUN
aji-66	228	20	have	have	VERB
aji-66	228	21	a	a	DET
aji-66	228	22	track	track	NOUN
aji-66	228	23	record	record	NOUN
aji-66	228	24	for	for	ADP
aji-66	228	25	production	production	NOUN
aji-66	228	26	of	of	ADP
aji-66	228	27	recombinant	recombinant	ADJ
aji-66	228	28	malaria	malaria	NOUN
aji-66	228	29	antigens	antigen	NOUN
aji-66	228	30	the	the	DET
aji-66	228	31	reported	report	VERB
aji-66	228	32	yields	yield	NOUN
aji-66	228	33	of	of	ADP
aji-66	228	34	properly	properly	ADV
aji-66	228	35	folded	fold	VERB
aji-66	228	36	recombinant	recombinant	ADJ
aji-66	228	37	pfs48/45	pfs48/45	NOUN
aji-66	228	38	have	have	AUX
aji-66	228	39	been	be	AUX
aji-66	228	40	disappointingly	disappointingly	ADV
aji-66	228	41	low	low	ADJ
aji-66	229	1	[	[	X
aji-66	229	2	38,39	38,39	NOUN
aji-66	229	3	]	]	X
aji-66	229	4	.	.	PUNCT
aji-66	230	1	4.2	4.2	NUM
aji-66	230	2	preclinical	preclinical	ADJ
aji-66	230	3	studies	study	NOUN
aji-66	230	4	numerous	numerous	ADJ
aji-66	230	5	animal	animal	NOUN
aji-66	230	6	studies	study	NOUN
aji-66	230	7	have	have	AUX
aji-66	230	8	shown	show	VERB
aji-66	230	9	that	that	PRON
aji-66	230	10	pfs48/45	pfs48/45	NOUN
aji-66	230	11	,	,	PUNCT
aji-66	230	12	pfs25	pfs25	NOUN
aji-66	230	13	and	and	CCONJ
aji-66	230	14	other	other	ADJ
aji-66	230	15	candidates	candidate	NOUN
aji-66	230	16	vaccination	vaccination	NOUN
aji-66	230	17	elicits	elicit	VERB
aji-66	230	18	antibodies	antibodie	VERB
aji-66	230	19	with	with	ADP
aji-66	230	20	the	the	DET
aji-66	230	21	capacity	capacity	NOUN
aji-66	230	22	to	to	PART
aji-66	230	23	inhibit	inhibit	VERB
aji-66	230	24	parasite	parasite	ADJ
aji-66	230	25	fertilization	fertilization	NOUN
aji-66	230	26	in	in	ADP
aji-66	230	27	mosquitoes	mosquito	NOUN
aji-66	230	28	as	as	SCONJ
aji-66	230	29	determined	determine	VERB
aji-66	230	30	in	in	ADP
aji-66	230	31	the	the	DET
aji-66	230	32	smfa	smfa	NOUN
aji-66	230	33	[	[	X
aji-66	230	34	28	28	NUM
aji-66	230	35	]	]	PUNCT
aji-66	230	36	.	.	PUNCT
aji-66	231	1	in	in	ADP
aji-66	231	2	general	general	ADJ
aji-66	231	3	,	,	PUNCT
aji-66	231	4	a	a	DET
aji-66	231	5	recombinant	recombinant	ADJ
aji-66	231	6	protein	protein	NOUN
aji-66	231	7	which	which	PRON
aji-66	231	8	assumes	assume	VERB
aji-66	231	9	a	a	DET
aji-66	231	10	proper	proper	ADJ
aji-66	231	11	fold	fold	NOUN
aji-66	231	12	,	,	PUNCT
aji-66	231	13	as	as	SCONJ
aji-66	231	14	determined	determine	VERB
aji-66	231	15	by	by	ADP
aji-66	231	16	the	the	DET
aji-66	231	17	reactivity	reactivity	NOUN
aji-66	231	18	with	with	ADP
aji-66	231	19	mabs	mab	NOUN
aji-66	231	20	against	against	ADP
aji-66	231	21	conformational	conformational	ADJ
aji-66	231	22	epitopes	epitope	NOUN
aji-66	231	23	,	,	PUNCT
aji-66	231	24	elicits	elicit	VERB
aji-66	231	25	high	high	ADJ
aji-66	231	26	levels	level	NOUN
aji-66	231	27	of	of	ADP
aji-66	231	28	transmission	transmission	NOUN
aji-66	231	29	-	-	PUNCT
aji-66	231	30	blocking	block	VERB
aji-66	231	31	antibodies	antibody	NOUN
aji-66	231	32	[	[	X
aji-66	231	33	21	21	NUM
aji-66	231	34	]	]	PUNCT
aji-66	231	35	.	.	PUNCT
aji-66	232	1	in	in	ADP
aji-66	232	2	contrast	contrast	NOUN
aji-66	232	3	,	,	PUNCT
aji-66	232	4	miss	miss	NOUN
aji-66	232	5	-	-	PUNCT
aji-66	232	6	folded	fold	VERB
aji-66	232	7	protein	protein	NOUN
aji-66	232	8	does	do	AUX
aji-66	232	9	not	not	PART
aji-66	232	10	elicit	elicit	VERB
aji-66	232	11	transmission	transmission	NOUN
aji-66	232	12	-	-	PUNCT
aji-66	232	13	blocking	block	VERB
aji-66	232	14	antibodies	antibody	NOUN
aji-66	232	15	suggesting	suggest	VERB
aji-66	232	16	that	that	SCONJ
aji-66	232	17	correct	correct	ADJ
aji-66	232	18	folding	folding	NOUN
aji-66	232	19	of	of	ADP
aji-66	232	20	critical	critical	ADJ
aji-66	232	21	epitopes	epitope	NOUN
aji-66	232	22	involved	involve	VERB
aji-66	232	23	in	in	ADP
aji-66	232	24	transmission	transmission	NOUN
aji-66	232	25	-	-	PUNCT
aji-66	232	26	blocking	block	VERB
aji-66	232	27	immunity	immunity	NOUN
aji-66	232	28	is	be	AUX
aji-66	232	29	essential	essential	ADJ
aji-66	232	30	for	for	ADP
aji-66	232	31	an	an	DET
aji-66	232	32	efficacious	efficacious	ADJ
aji-66	232	33	tbv	tbv	NOUN
aji-66	233	1	[	[	X
aji-66	233	2	21	21	NUM
aji-66	233	3	]	]	PUNCT
aji-66	233	4	.	.	PUNCT
aji-66	234	1	adjuvants	adjuvant	NOUN
aji-66	234	2	are	be	AUX
aji-66	234	3	vital	vital	ADJ
aji-66	234	4	for	for	ADP
aji-66	234	5	an	an	DET
aji-66	234	6	efficacious	efficacious	ADJ
aji-66	234	7	subunit	subunit	NOUN
aji-66	234	8	-	-	PUNCT
aji-66	234	9	vaccine	vaccine	NOUN
aji-66	234	10	by	by	ADP
aji-66	234	11	enhancing	enhance	VERB
aji-66	234	12	seroconversion	seroconversion	NOUN
aji-66	234	13	rates	rate	NOUN
aji-66	234	14	and	and	CCONJ
aji-66	234	15	concentrations	concentration	NOUN
aji-66	234	16	of	of	ADP
aji-66	234	17	functional	functional	ADJ
aji-66	234	18	antibodies	antibody	NOUN
aji-66	234	19	[	[	X
aji-66	234	20	40	40	NUM
aji-66	234	21	]	]	PUNCT
aji-66	234	22	.	.	PUNCT
aji-66	235	1	in	in	ADP
aji-66	235	2	the	the	DET
aji-66	235	3	preclinical	preclinical	ADJ
aji-66	235	4	wangai	wangai	NOUN
aji-66	235	5	et	et	PROPN
aji-66	235	6	al	al	PROPN
aji-66	235	7	.	.	PROPN
aji-66	235	8	;	;	PUNCT
aji-66	235	9	aji	aji	PROPN
aji-66	235	10	,	,	PUNCT
aji-66	235	11	4(1	4(1	NOUN
aji-66	235	12	):	):	PUNCT
aji-66	235	13	77	77	NUM
aji-66	235	14	-	-	SYM
aji-66	235	15	84	84	NUM
aji-66	235	16	,	,	PUNCT
aji-66	235	17	2021	2021	NUM
aji-66	235	18	;	;	PUNCT
aji-66	235	19	article	article	NOUN
aji-66	235	20	no.aji.69854	no.aji.69854	NOUN
aji-66	235	21	82	82	NUM
aji-66	235	22	adjuvant	adjuvant	ADJ
aji-66	235	23	selection	selection	NOUN
aji-66	235	24	,	,	PUNCT
aji-66	235	25	it	it	PRON
aji-66	235	26	is	be	AUX
aji-66	235	27	important	important	ADJ
aji-66	235	28	to	to	PART
aji-66	235	29	focus	focus	VERB
aji-66	235	30	on	on	ADP
aji-66	235	31	those	those	PRON
aji-66	235	32	with	with	ADP
aji-66	235	33	a	a	DET
aji-66	235	34	human	human	ADJ
aji-66	235	35	clinical	clinical	ADJ
aji-66	235	36	development	development	NOUN
aji-66	235	37	path	path	NOUN
aji-66	235	38	with	with	ADP
aji-66	235	39	records	record	NOUN
aji-66	235	40	of	of	ADP
aji-66	235	41	both	both	DET
aji-66	235	42	safety	safety	NOUN
aji-66	235	43	and	and	CCONJ
aji-66	235	44	manufacturability	manufacturability	NOUN
aji-66	235	45	[	[	X
aji-66	235	46	28	28	NUM
aji-66	235	47	]	]	PUNCT
aji-66	235	48	.	.	PUNCT
aji-66	236	1	whether	whether	SCONJ
aji-66	236	2	this	this	DET
aji-66	236	3	level	level	NOUN
aji-66	236	4	of	of	ADP
aji-66	236	5	vaccine	vaccine	NOUN
aji-66	236	6	-	-	PUNCT
aji-66	236	7	specific	specific	ADJ
aji-66	236	8	antibodies	antibody	NOUN
aji-66	236	9	is	be	AUX
aji-66	236	10	comparable	comparable	ADJ
aji-66	236	11	to	to	ADP
aji-66	236	12	naturally	naturally	ADV
aji-66	236	13	occurring	occur	VERB
aji-66	236	14	antibodies	antibody	NOUN
aji-66	236	15	against	against	ADP
aji-66	236	16	pfs48/45	pfs48/45	NOUN
aji-66	236	17	is	be	AUX
aji-66	236	18	unknown	unknown	ADJ
aji-66	236	19	.	.	PUNCT
aji-66	237	1	this	this	PRON
aji-66	237	2	is	be	AUX
aji-66	237	3	mainly	mainly	ADV
aji-66	237	4	because	because	SCONJ
aji-66	237	5	most	most	ADJ
aji-66	237	6	studies	study	NOUN
aji-66	237	7	of	of	ADP
aji-66	237	8	naturally	naturally	ADV
aji-66	237	9	acquired	acquire	VERB
aji-66	237	10	immunity	immunity	NOUN
aji-66	237	11	have	have	AUX
aji-66	237	12	reported	report	VERB
aji-66	237	13	antibody	antibody	NOUN
aji-66	237	14	data	datum	NOUN
aji-66	237	15	as	as	ADP
aji-66	237	16	categorical	categorical	ADJ
aji-66	237	17	variables	variable	NOUN
aji-66	237	18	(	(	PUNCT
aji-66	237	19	either	either	CCONJ
aji-66	237	20	positive	positive	ADJ
aji-66	237	21	or	or	CCONJ
aji-66	237	22	negative	negative	ADJ
aji-66	237	23	)	)	PUNCT
aji-66	237	24	rather	rather	ADV
aji-66	237	25	than	than	ADP
aji-66	237	26	continuous	continuous	ADJ
aji-66	237	27	variable	variable	NOUN
aji-66	237	28	.	.	PUNCT
aji-66	238	1	the	the	DET
aji-66	238	2	availability	availability	NOUN
aji-66	238	3	of	of	ADP
aji-66	238	4	new	new	ADJ
aji-66	238	5	recombinant	recombinant	ADJ
aji-66	238	6	proteins	protein	NOUN
aji-66	238	7	will	will	AUX
aji-66	238	8	help	help	VERB
aji-66	238	9	future	future	ADJ
aji-66	238	10	studies	study	NOUN
aji-66	238	11	to	to	PART
aji-66	238	12	estimate	estimate	VERB
aji-66	238	13	the	the	DET
aji-66	238	14	level	level	NOUN
aji-66	238	15	of	of	ADP
aji-66	238	16	vaccinespecific	vaccinespecific	NOUN
aji-66	238	17	as	as	ADV
aji-66	238	18	well	well	ADV
aji-66	238	19	as	as	ADP
aji-66	238	20	naturally	naturally	ADV
aji-66	238	21	acquired	acquire	VERB
aji-66	238	22	antibodies	antibody	NOUN
aji-66	238	23	.	.	PUNCT
aji-66	239	1	the	the	DET
aji-66	239	2	ability	ability	NOUN
aji-66	239	3	of	of	ADP
aji-66	239	4	newly	newly	ADV
aji-66	239	5	designed	design	VERB
aji-66	239	6	adjuvants	adjuvant	NOUN
aji-66	239	7	to	to	PART
aji-66	239	8	enhance	enhance	VERB
aji-66	239	9	levels	level	NOUN
aji-66	239	10	of	of	ADP
aji-66	239	11	functional	functional	ADJ
aji-66	239	12	antibodies	antibody	NOUN
aji-66	239	13	against	against	ADP
aji-66	239	14	pfs48/45	pfs48/45	NOUN
aji-66	239	15	has	have	AUX
aji-66	239	16	been	be	AUX
aji-66	239	17	investigated	investigate	VERB
aji-66	239	18	in	in	ADP
aji-66	239	19	small	small	ADJ
aji-66	239	20	rodents	rodent	NOUN
aji-66	239	21	using	use	VERB
aji-66	239	22	recombinant	recombinant	ADJ
aji-66	239	23	proteins	protein	NOUN
aji-66	239	24	produced	produce	VERB
aji-66	239	25	in	in	ADP
aji-66	239	26	the	the	DET
aji-66	239	27	l.	l.	PROPN
aji-66	239	28	lactis	lactis	PROPN
aji-66	239	29	expression	expression	NOUN
aji-66	239	30	system	system	NOUN
aji-66	239	31	[	[	X
aji-66	239	32	6	6	NUM
aji-66	239	33	]	]	PUNCT
aji-66	239	34	.	.	PUNCT
aji-66	240	1	formulations	formulation	NOUN
aji-66	240	2	containing	contain	VERB
aji-66	240	3	the	the	DET
aji-66	240	4	synthetic	synthetic	ADJ
aji-66	240	5	tlr4	tlr4	NOUN
aji-66	240	6	agonist	agonist	NOUN
aji-66	240	7	glucopyranosyl	glucopyranosyl	NOUN
aji-66	240	8	lipid	lipid	NOUN
aji-66	240	9	adjuvant	adjuvant	NOUN
aji-66	240	10	(	(	PUNCT
aji-66	240	11	gla	gla	PROPN
aji-66	240	12	)	)	PUNCT
aji-66	240	13	or	or	CCONJ
aji-66	240	14	a	a	DET
aji-66	240	15	combination	combination	NOUN
aji-66	240	16	of	of	ADP
aji-66	240	17	synthetic	synthetic	ADJ
aji-66	240	18	lipid	lipid	NOUN
aji-66	240	19	adjuvant	adjuvant	NOUN
aji-66	240	20	(	(	PUNCT
aji-66	240	21	sla	sla	PROPN
aji-66	240	22	)	)	PUNCT
aji-66	240	23	and	and	CCONJ
aji-66	240	24	saponin	saponin	NOUN
aji-66	240	25	containing	contain	VERB
aji-66	240	26	qs21	qs21	PROPN
aji-66	240	27	in	in	ADP
aji-66	240	28	a	a	DET
aji-66	240	29	liposome	liposome	NOUN
aji-66	240	30	formulation	formulation	NOUN
aji-66	240	31	(	(	PUNCT
aji-66	240	32	sla	sla	PROPN
aji-66	240	33	-	-	PUNCT
aji-66	240	34	lsq	lsq	PROPN
aji-66	240	35	)	)	PUNCT
aji-66	240	36	induce	induce	VERB
aji-66	240	37	the	the	DET
aji-66	240	38	highest	high	ADJ
aji-66	240	39	titers	titer	NOUN
aji-66	240	40	of	of	ADP
aji-66	240	41	antibodies	antibody	NOUN
aji-66	240	42	to	to	ADP
aji-66	240	43	sexual	sexual	ADJ
aji-66	240	44	stage	stage	NOUN
aji-66	240	45	antigens	antigen	NOUN
aji-66	240	46	.	.	PUNCT
aji-66	241	1	both	both	CCONJ
aji-66	241	2	the	the	DET
aji-66	241	3	gla	gla	PROPN
aji-66	241	4	and	and	CCONJ
aji-66	241	5	sla	sla	PROPN
aji-66	241	6	agonists	agonist	NOUN
aji-66	241	7	have	have	AUX
aji-66	241	8	been	be	AUX
aji-66	241	9	assessed	assess	VERB
aji-66	241	10	in	in	ADP
aji-66	241	11	human	human	ADJ
aji-66	241	12	clinical	clinical	ADJ
aji-66	241	13	trials	trial	NOUN
aji-66	241	14	as	as	ADP
aji-66	241	15	a	a	DET
aji-66	241	16	part	part	NOUN
aji-66	241	17	of	of	ADP
aji-66	241	18	vaccines	vaccine	NOUN
aji-66	241	19	against	against	ADP
aji-66	241	20	several	several	ADJ
aji-66	241	21	infectious	infectious	ADJ
aji-66	241	22	diseases	disease	NOUN
aji-66	241	23	suggesting	suggest	VERB
aji-66	241	24	they	they	PRON
aji-66	241	25	might	might	AUX
aji-66	241	26	be	be	AUX
aji-66	241	27	useful	useful	ADJ
aji-66	241	28	for	for	ADP
aji-66	241	29	the	the	DET
aji-66	241	30	development	development	NOUN
aji-66	241	31	of	of	ADP
aji-66	241	32	a	a	DET
aji-66	241	33	tbv[35	tbv[35	PROPN
aji-66	241	34	]	]	PUNCT
aji-66	241	35	.	.	PUNCT
aji-66	242	1	viral	viral	ADJ
aji-66	242	2	vectors	vector	NOUN
aji-66	242	3	are	be	AUX
aji-66	242	4	considered	consider	VERB
aji-66	242	5	an	an	DET
aji-66	242	6	attractive	attractive	ADJ
aji-66	242	7	alternative	alternative	NOUN
aji-66	242	8	to	to	ADP
aji-66	242	9	protein	protein	NOUN
aji-66	242	10	-	-	PUNCT
aji-66	242	11	based	base	VERB
aji-66	242	12	vaccines	vaccine	NOUN
aji-66	242	13	because	because	SCONJ
aji-66	242	14	they	they	PRON
aji-66	242	15	circumvent	circumvent	VERB
aji-66	242	16	the	the	DET
aji-66	242	17	need	need	NOUN
aji-66	242	18	for	for	ADP
aji-66	242	19	production	production	NOUN
aji-66	242	20	and	and	CCONJ
aji-66	242	21	purification	purification	NOUN
aji-66	242	22	of	of	ADP
aji-66	242	23	properly	properly	ADV
aji-66	242	24	folded	fold	VERB
aji-66	242	25	protein	protein	NOUN
aji-66	242	26	and	and	CCONJ
aji-66	242	27	because	because	SCONJ
aji-66	242	28	of	of	ADP
aji-66	242	29	their	their	PRON
aji-66	242	30	ability	ability	NOUN
aji-66	242	31	to	to	PART
aji-66	242	32	effectively	effectively	ADV
aji-66	242	33	induce	induce	VERB
aji-66	242	34	both	both	CCONJ
aji-66	242	35	humoral	humoral	ADJ
aji-66	242	36	and	and	CCONJ
aji-66	242	37	cell	cell	NOUN
aji-66	242	38	-	-	PUNCT
aji-66	242	39	mediated	mediate	VERB
aji-66	242	40	immune	immune	ADJ
aji-66	242	41	responses	response	NOUN
aji-66	243	1	[	[	X
aji-66	243	2	9	9	NUM
aji-66	243	3	]	]	PUNCT
aji-66	243	4	.	.	PUNCT
aji-66	244	1	in	in	ADP
aji-66	244	2	recent	recent	ADJ
aji-66	244	3	years	year	NOUN
aji-66	244	4	this	this	DET
aji-66	244	5	approach	approach	NOUN
aji-66	244	6	has	have	AUX
aji-66	244	7	been	be	AUX
aji-66	244	8	explored	explore	VERB
aji-66	244	9	extensively	extensively	ADV
aji-66	244	10	[	[	X
aji-66	244	11	41	41	NUM
aji-66	244	12	]	]	PUNCT
aji-66	244	13	.	.	PUNCT
aji-66	245	1	for	for	ADP
aji-66	245	2	instance	instance	NOUN
aji-66	245	3	,	,	PUNCT
aji-66	245	4	pfs48/45	pfs48/45	VERB
aji-66	245	5	has	have	AUX
aji-66	245	6	been	be	AUX
aji-66	245	7	tested	test	VERB
aji-66	245	8	in	in	ADP
aji-66	245	9	a	a	DET
aji-66	245	10	chad63	chad63	NOUN
aji-66	245	11	-	-	PUNCT
aji-66	245	12	mva	mva	NOUN
aji-66	245	13	heterologous	heterologous	ADJ
aji-66	245	14	prime	prime	ADJ
aji-66	245	15	-	-	PUNCT
aji-66	245	16	boost	boost	NOUN
aji-66	245	17	regime	regime	NOUN
aji-66	245	18	as	as	ADP
aji-66	245	19	a	a	DET
aji-66	245	20	glycosylated	glycosylated	ADJ
aji-66	245	21	and	and	CCONJ
aji-66	245	22	nonglycosylated	nonglycosylate	VERB
aji-66	245	23	recombinant	recombinant	ADJ
aji-66	245	24	protein	protein	NOUN
aji-66	245	25	[	[	X
aji-66	245	26	42	42	NUM
aji-66	245	27	]	]	PUNCT
aji-66	245	28	.	.	PUNCT
aji-66	246	1	mouse	mouse	PROPN
aji-66	246	2	igg	igg	PROPN
aji-66	246	3	against	against	ADP
aji-66	246	4	non	non	ADJ
aji-66	246	5	-	-	ADJ
aji-66	246	6	glycosylated	glycosylated	ADJ
aji-66	246	7	pfs48/45	pfs48/45	NOUN
aji-66	246	8	shows	show	VERB
aji-66	246	9	transmission	transmission	NOUN
aji-66	246	10	-	-	PUNCT
aji-66	246	11	blocking	block	VERB
aji-66	246	12	activity	activity	NOUN
aji-66	246	13	in	in	ADP
aji-66	246	14	smfa	smfa	NOUN
aji-66	246	15	using	use	VERB
aji-66	246	16	homologous	homologous	ADJ
aji-66	246	17	nf54	nf54	PROPN
aji-66	246	18	parasites	parasite	NOUN
aji-66	246	19	and	and	CCONJ
aji-66	246	20	to	to	ADP
aji-66	246	21	a	a	DET
aji-66	246	22	lesser	less	ADJ
aji-66	246	23	extent	extent	NOUN
aji-66	246	24	also	also	ADV
aji-66	246	25	in	in	ADP
aji-66	246	26	the	the	DET
aji-66	246	27	direct	direct	ADJ
aji-66	246	28	membrane	membrane	NOUN
aji-66	246	29	feeding	feeding	NOUN
aji-66	246	30	assay	assay	NOUN
aji-66	246	31	(	(	PUNCT
aji-66	246	32	dmfa	dmfa	NOUN
aji-66	246	33	)	)	PUNCT
aji-66	246	34	using	use	VERB
aji-66	246	35	p.	p.	NOUN
aji-66	246	36	falciparum	falciparum	ADJ
aji-66	246	37	parasites	parasite	NOUN
aji-66	246	38	collected	collect	VERB
aji-66	246	39	from	from	ADP
aji-66	246	40	naturally	naturally	ADV
aji-66	246	41	exposed	expose	VERB
aji-66	246	42	gametocyte	gametocyte	NOUN
aji-66	246	43	donors	donor	NOUN
aji-66	246	44	[	[	X
aji-66	246	45	6	6	NUM
aji-66	246	46	]	]	PUNCT
aji-66	246	47	.	.	PUNCT
aji-66	247	1	collectively	collectively	ADV
aji-66	247	2	,	,	PUNCT
aji-66	247	3	these	these	DET
aji-66	247	4	findings	finding	NOUN
aji-66	247	5	suggest	suggest	VERB
aji-66	247	6	that	that	SCONJ
aji-66	247	7	pfs25	pfs25	NOUN
aji-66	247	8	and	and	CCONJ
aji-66	247	9	pfs48/45	pfs48/45	NOUN
aji-66	247	10	-	-	PUNCT
aji-66	247	11	based	base	VERB
aji-66	247	12	subunit	subunit	NOUN
aji-66	247	13	vaccines	vaccine	NOUN
aji-66	247	14	have	have	VERB
aji-66	247	15	the	the	DET
aji-66	247	16	capacity	capacity	NOUN
aji-66	247	17	to	to	PART
aji-66	247	18	elicit	elicit	VERB
aji-66	247	19	functional	functional	ADJ
aji-66	247	20	antibodies	antibody	NOUN
aji-66	247	21	in	in	ADP
aji-66	247	22	humans	human	NOUN
aji-66	247	23	.	.	PUNCT
aji-66	248	1	5	5	X
aji-66	248	2	.	.	X
aji-66	248	3	conclusion	conclusion	NOUN
aji-66	248	4	this	this	DET
aji-66	248	5	review	review	NOUN
aji-66	248	6	highlights	highlight	VERB
aji-66	248	7	the	the	DET
aji-66	248	8	need	need	NOUN
aji-66	248	9	to	to	PART
aji-66	248	10	develop	develop	VERB
aji-66	248	11	novel	novel	ADJ
aji-66	248	12	malaria	malaria	NOUN
aji-66	248	13	elimination	elimination	NOUN
aji-66	248	14	interventions	intervention	NOUN
aji-66	248	15	in	in	ADP
aji-66	248	16	particular	particular	ADJ
aji-66	248	17	an	an	DET
aji-66	248	18	effective	effective	ADJ
aji-66	248	19	malaria	malaria	NOUN
aji-66	248	20	vaccine	vaccine	NOUN
aji-66	248	21	with	with	ADP
aji-66	248	22	transmissionblocking	transmissionblocke	VERB
aji-66	248	23	activity	activity	NOUN
aji-66	248	24	.	.	PUNCT
aji-66	249	1	pfs25	pfs25	NOUN
aji-66	249	2	and	and	CCONJ
aji-66	249	3	pfs48/45	pfs48/45	NOUN
aji-66	249	4	are	be	AUX
aji-66	249	5	essential	essential	ADJ
aji-66	249	6	lead	lead	NOUN
aji-66	249	7	-	-	PUNCT
aji-66	249	8	candidates	candidate	NOUN
aji-66	249	9	for	for	ADP
aji-66	249	10	a	a	DET
aji-66	249	11	transmissionblocking	transmissionblocking	NOUN
aji-66	249	12	vaccine	vaccine	NOUN
aji-66	249	13	and	and	CCONJ
aji-66	249	14	should	should	AUX
aji-66	249	15	be	be	AUX
aji-66	249	16	explored	explore	VERB
aji-66	249	17	further	far	ADV
aji-66	249	18	in	in	ADP
aji-66	249	19	clinical	clinical	ADJ
aji-66	249	20	trials	trial	NOUN
aji-66	249	21	.	.	PUNCT
aji-66	250	1	consent	consent	NOUN
aji-66	250	2	it	it	PRON
aji-66	250	3	is	be	AUX
aji-66	250	4	not	not	PART
aji-66	250	5	applicable	applicable	ADJ
aji-66	250	6	.	.	PUNCT
aji-66	251	1	ethical	ethical	ADJ
aji-66	251	2	approval	approval	NOUN
aji-66	251	3	it	it	PRON
aji-66	251	4	is	be	AUX
aji-66	251	5	not	not	PART
aji-66	251	6	applicable	applicable	ADJ
aji-66	251	7	.	.	PUNCT
aji-66	252	1	competing	compete	VERB
aji-66	252	2	interests	interest	NOUN
aji-66	252	3	authors	author	NOUN
aji-66	252	4	have	have	AUX
aji-66	252	5	declared	declare	VERB
aji-66	252	6	that	that	SCONJ
aji-66	252	7	no	no	DET
aji-66	252	8	competing	compete	VERB
aji-66	252	9	interests	interest	NOUN
aji-66	252	10	exist	exist	VERB
aji-66	252	11	.	.	PUNCT
aji-66	253	1	references	reference	NOUN
aji-66	253	2	1	1	NUM
aji-66	253	3	.	.	PUNCT
aji-66	253	4	world	world	PROPN
aji-66	253	5	health	health	PROPN
aji-66	253	6	organization	organization	PROPN
aji-66	253	7	.	.	PUNCT
aji-66	254	1	world	world	NOUN
aji-66	254	2	malaria	malaria	PROPN
aji-66	254	3	report	report	NOUN
aji-66	254	4	2020	2020	NUM
aji-66	254	5	:	:	PUNCT
aji-66	254	6	20	20	NUM
aji-66	254	7	years	year	NOUN
aji-66	254	8	of	of	ADP
aji-66	254	9	global	global	ADJ
aji-66	254	10	progress	progress	NOUN
aji-66	254	11	and	and	CCONJ
aji-66	254	12	challenges	challenge	NOUN
aji-66	254	13	;	;	PUNCT
aji-66	254	14	2020	2020	NUM
aji-66	254	15	.	.	X
aji-66	255	1	2	2	X
aji-66	255	2	.	.	X
aji-66	255	3	alonso	alonso	PROPN
aji-66	255	4	p	p	X
aji-66	255	5	,	,	PUNCT
aji-66	255	6	noor	noor	PROPN
aji-66	255	7	am	be	AUX
aji-66	255	8	.	.	PUNCT
aji-66	256	1	the	the	DET
aji-66	256	2	global	global	ADJ
aji-66	256	3	fight	fight	NOUN
aji-66	256	4	against	against	ADP
aji-66	256	5	malaria	malaria	NOUN
aji-66	256	6	is	be	AUX
aji-66	256	7	at	at	ADP
aji-66	256	8	crossroads	crossroad	NOUN
aji-66	256	9	.	.	PUNCT
aji-66	257	1	the	the	DET
aji-66	257	2	lancet	lancet	NOUN
aji-66	257	3	.	.	PUNCT
aji-66	258	1	2017;390(10112):2532–4	2017;390(10112):2532–4	NUM
aji-66	258	2	.	.	PUNCT
aji-66	259	1	3	3	X
aji-66	259	2	.	.	X
aji-66	259	3	dondorp	dondorp	PROPN
aji-66	259	4	am	be	AUX
aji-66	259	5	,	,	PUNCT
aji-66	259	6	yeung	yeung	PROPN
aji-66	259	7	s	s	PROPN
aji-66	259	8	,	,	PUNCT
aji-66	259	9	white	white	PROPN
aji-66	259	10	l	l	PROPN
aji-66	259	11	,	,	PUNCT
aji-66	259	12	nguon	nguon	NOUN
aji-66	259	13	c	c	NOUN
aji-66	259	14	,	,	PUNCT
aji-66	259	15	day	day	NOUN
aji-66	259	16	np	np	NOUN
aji-66	259	17	,	,	PUNCT
aji-66	259	18	socheat	socheat	NOUN
aji-66	259	19	d	d	NOUN
aji-66	259	20	,	,	PUNCT
aji-66	259	21	et	et	PROPN
aji-66	259	22	al	al	PROPN
aji-66	259	23	.	.	PUNCT
aji-66	260	1	artemisinin	artemisinin	PROPN
aji-66	260	2	resistance	resistance	PROPN
aji-66	260	3	:	:	PUNCT
aji-66	260	4	current	current	ADJ
aji-66	260	5	status	status	NOUN
aji-66	260	6	and	and	CCONJ
aji-66	260	7	scenarios	scenario	NOUN
aji-66	260	8	for	for	ADP
aji-66	260	9	containment	containment	NOUN
aji-66	260	10	.	.	PUNCT
aji-66	261	1	nat	nat	PROPN
aji-66	261	2	rev	rev	PROPN
aji-66	261	3	microbiol	microbiol	PROPN
aji-66	261	4	.	.	PUNCT
aji-66	262	1	2010;8(4):272–80	2010;8(4):272–80	NUM
aji-66	262	2	.	.	PUNCT
aji-66	263	1	4	4	X
aji-66	263	2	.	.	X
aji-66	263	3	kaslow	kaslow	PROPN
aji-66	263	4	dc	dc	PROPN
aji-66	263	5	.	.	PUNCT
aji-66	264	1	transmission	transmission	NOUN
aji-66	264	2	-	-	PUNCT
aji-66	264	3	blocking	block	VERB
aji-66	264	4	vaccines	vaccine	NOUN
aji-66	264	5	:	:	PUNCT
aji-66	264	6	uses	use	NOUN
aji-66	264	7	and	and	CCONJ
aji-66	264	8	current	current	ADJ
aji-66	264	9	status	status	NOUN
aji-66	264	10	of	of	ADP
aji-66	264	11	development	development	NOUN
aji-66	264	12	.	.	PUNCT
aji-66	265	1	int	int	PROPN
aji-66	265	2	j	j	PROPN
aji-66	265	3	parasitol	parasitol	NOUN
aji-66	265	4	.	.	PUNCT
aji-66	266	1	1997;27(2):183–9	1997;27(2):183–9	NUM
aji-66	266	2	.	.	PUNCT
aji-66	267	1	5	5	X
aji-66	267	2	.	.	X
aji-66	267	3	carter	carter	PROPN
aji-66	267	4	r.	r.	PROPN
aji-66	267	5	transmission	transmission	NOUN
aji-66	267	6	blocking	block	VERB
aji-66	267	7	malaria	malaria	NOUN
aji-66	267	8	vaccines	vaccine	NOUN
aji-66	267	9	.	.	PUNCT
aji-66	268	1	vaccine	vaccine	NOUN
aji-66	268	2	.	.	PUNCT
aji-66	269	1	2001;19(17–19):2309	2001;19(17–19):2309	NUM
aji-66	269	2	–	–	PUNCT
aji-66	269	3	14	14	NUM
aji-66	269	4	.	.	NOUN
aji-66	270	1	6	6	NUM
aji-66	270	2	.	.	PUNCT
aji-66	270	3	theisen	theisen	PROPN
aji-66	270	4	m	m	PROPN
aji-66	270	5	,	,	PUNCT
aji-66	270	6	jore	jore	PROPN
aji-66	270	7	mm	mm	PROPN
aji-66	270	8	,	,	PUNCT
aji-66	270	9	sauerwein	sauerwein	PROPN
aji-66	270	10	r.	r.	PROPN
aji-66	270	11	towards	towards	ADP
aji-66	270	12	clinical	clinical	ADJ
aji-66	270	13	development	development	NOUN
aji-66	270	14	of	of	ADP
aji-66	270	15	a	a	DET
aji-66	270	16	pf	pf	PROPN
aji-66	270	17	s48/45	s48/45	PROPN
aji-66	270	18	-	-	PUNCT
aji-66	270	19	based	base	VERB
aji-66	270	20	transmission	transmission	NOUN
aji-66	270	21	blocking	block	VERB
aji-66	270	22	malaria	malaria	NOUN
aji-66	270	23	vaccine	vaccine	NOUN
aji-66	270	24	.	.	PUNCT
aji-66	271	1	expert	expert	NOUN
aji-66	271	2	rev	rev	VERB
aji-66	271	3	vaccines	vaccine	NOUN
aji-66	271	4	.	.	PUNCT
aji-66	272	1	2017;16(4):329–36	2017;16(4):329–36	NUM
aji-66	272	2	.	.	PUNCT
aji-66	273	1	7	7	X
aji-66	273	2	.	.	X
aji-66	273	3	bompard	bompard	PROPN
aji-66	273	4	a	a	PRON
aji-66	273	5	,	,	PUNCT
aji-66	273	6	da	da	PROPN
aji-66	273	7	df	df	PROPN
aji-66	273	8	,	,	PUNCT
aji-66	273	9	yerbanga	yerbanga	ADV
aji-66	273	10	rs	r	NOUN
aji-66	273	11	,	,	PUNCT
aji-66	273	12	biswas	biswas	PROPN
aji-66	273	13	s	s	PROPN
aji-66	273	14	,	,	PUNCT
aji-66	273	15	kapulu	kapulu	VERB
aji-66	273	16	m	m	PROPN
aji-66	273	17	,	,	PUNCT
aji-66	273	18	bousema	bousema	PROPN
aji-66	273	19	t	t	PROPN
aji-66	273	20	,	,	PUNCT
aji-66	273	21	et	et	PROPN
aji-66	273	22	al	al	PROPN
aji-66	273	23	.	.	PUNCT
aji-66	273	24	evaluation	evaluation	NOUN
aji-66	273	25	of	of	ADP
aji-66	273	26	two	two	NUM
aji-66	273	27	lead	lead	NOUN
aji-66	273	28	malaria	malaria	NOUN
aji-66	273	29	transmission	transmission	NOUN
aji-66	273	30	blocking	block	VERB
aji-66	273	31	vaccine	vaccine	NOUN
aji-66	273	32	candidate	candidate	NOUN
aji-66	273	33	antibodies	antibodie	VERB
aji-66	273	34	in	in	ADP
aji-66	273	35	natural	natural	ADJ
aji-66	273	36	parasite	parasite	NOUN
aji-66	273	37	-	-	PUNCT
aji-66	273	38	vector	vector	NOUN
aji-66	273	39	combinations	combination	NOUN
aji-66	273	40	.	.	PUNCT
aji-66	274	1	sci	sci	PROPN
aji-66	274	2	rep	rep	PROPN
aji-66	274	3	.	.	PROPN
aji-66	274	4	2017;7(1):1–9	2017;7(1):1–9	PROPN
aji-66	274	5	.	.	PROPN
aji-66	274	6	8	8	NUM
aji-66	274	7	.	.	PUNCT
aji-66	274	8	wu	wu	PROPN
aji-66	274	9	y	y	PROPN
aji-66	274	10	,	,	PUNCT
aji-66	274	11	ellis	ellis	PROPN
aji-66	274	12	rd	rd	PROPN
aji-66	274	13	,	,	PUNCT
aji-66	274	14	shaffer	shaffer	PROPN
aji-66	274	15	d	d	PROPN
aji-66	274	16	,	,	PUNCT
aji-66	274	17	fontes	fonte	NOUN
aji-66	274	18	e	e	NOUN
aji-66	274	19	,	,	PUNCT
aji-66	274	20	malkin	malkin	PROPN
aji-66	274	21	em	em	PRON
aji-66	274	22	,	,	PUNCT
aji-66	274	23	mahanty	mahanty	NOUN
aji-66	274	24	s	s	X
aji-66	274	25	,	,	PUNCT
aji-66	275	1	et	et	PROPN
aji-66	275	2	al	al	PROPN
aji-66	275	3	.	.	PROPN
aji-66	275	4	phase	phase	NOUN
aji-66	275	5	1	1	NUM
aji-66	275	6	trial	trial	NOUN
aji-66	275	7	of	of	ADP
aji-66	275	8	malaria	malaria	NOUN
aji-66	275	9	transmission	transmission	NOUN
aji-66	275	10	blocking	block	VERB
aji-66	275	11	vaccine	vaccine	NOUN
aji-66	275	12	candidates	candidate	NOUN
aji-66	275	13	pfs25	pfs25	PROPN
aji-66	275	14	and	and	CCONJ
aji-66	275	15	pvs25	pvs25	AUX
aji-66	275	16	formulated	formulate	VERB
aji-66	275	17	with	with	ADP
aji-66	275	18	montanide	montanide	PROPN
aji-66	275	19	isa	isa	PROPN
aji-66	275	20	51	51	NUM
aji-66	275	21	.	.	PUNCT
aji-66	276	1	plos	plos	PROPN
aji-66	276	2	one	one	NUM
aji-66	276	3	.	.	PUNCT
aji-66	277	1	2008;3(7):e2636	2008;3(7):e2636	NOUN
aji-66	277	2	.	.	PUNCT
aji-66	278	1	9	9	NUM
aji-66	278	2	.	.	X
aji-66	278	3	stone	stone	PROPN
aji-66	278	4	w	w	PROPN
aji-66	278	5	,	,	PUNCT
aji-66	278	6	bousema	bousema	PROPN
aji-66	278	7	t	t	PROPN
aji-66	278	8	,	,	PUNCT
aji-66	278	9	sauerwein	sauerwein	ADJ
aji-66	278	10	r	r	NOUN
aji-66	278	11	,	,	PUNCT
aji-66	278	12	drakeley	drakeley	PROPN
aji-66	278	13	c.	c.	PROPN
aji-66	278	14	two	two	NUM
aji-66	278	15	-	-	PUNCT
aji-66	278	16	faced	face	VERB
aji-66	278	17	immunity	immunity	NOUN
aji-66	278	18	?	?	PUNCT
aji-66	279	1	the	the	DET
aji-66	279	2	wangai	wangai	INTJ
aji-66	279	3	et	et	PROPN
aji-66	279	4	al	al	PROPN
aji-66	279	5	.	.	PROPN
aji-66	279	6	;	;	PUNCT
aji-66	279	7	aji	aji	PROPN
aji-66	279	8	,	,	PUNCT
aji-66	279	9	4(1	4(1	NOUN
aji-66	279	10	):	):	PUNCT
aji-66	279	11	77	77	NUM
aji-66	279	12	-	-	SYM
aji-66	279	13	84	84	NUM
aji-66	279	14	,	,	PUNCT
aji-66	279	15	2021	2021	NUM
aji-66	279	16	;	;	PUNCT
aji-66	279	17	article	article	NOUN
aji-66	279	18	no.aji.69854	no.aji.69854	NOUN
aji-66	279	19	83	83	NUM
aji-66	279	20	evidence	evidence	NOUN
aji-66	279	21	for	for	ADP
aji-66	279	22	antibody	antibody	NOUN
aji-66	279	23	enhancement	enhancement	NOUN
aji-66	279	24	of	of	ADP
aji-66	279	25	malaria	malaria	NOUN
aji-66	279	26	transmission	transmission	NOUN
aji-66	279	27	.	.	PUNCT
aji-66	280	1	trends	trend	NOUN
aji-66	280	2	parasitol	parasitol	NOUN
aji-66	280	3	.	.	PUNCT
aji-66	281	1	2019;35(2):140–53	2019;35(2):140–53	NUM
aji-66	281	2	.	.	PUNCT
aji-66	282	1	10	10	NUM
aji-66	282	2	.	.	PUNCT
aji-66	283	1	acquah	acquah	PROPN
aji-66	283	2	fk	fk	PROPN
aji-66	283	3	,	,	PUNCT
aji-66	283	4	adjah	adjah	PROPN
aji-66	283	5	j	j	PROPN
aji-66	283	6	,	,	PUNCT
aji-66	283	7	williamson	williamson	PROPN
aji-66	283	8	kc	kc	PROPN
aji-66	283	9	,	,	PUNCT
aji-66	283	10	amoah	amoah	PROPN
aji-66	283	11	le	le	X
aji-66	283	12	.	.	PUNCT
aji-66	284	1	transmission	transmission	NOUN
aji-66	284	2	-	-	PUNCT
aji-66	284	3	blocking	block	VERB
aji-66	284	4	vaccines	vaccine	NOUN
aji-66	284	5	:	:	PUNCT
aji-66	284	6	old	old	ADJ
aji-66	284	7	friends	friend	NOUN
aji-66	284	8	and	and	CCONJ
aji-66	284	9	new	new	ADJ
aji-66	284	10	prospects	prospect	NOUN
aji-66	284	11	.	.	PUNCT
aji-66	285	1	infect	infect	VERB
aji-66	285	2	immun	immun	PROPN
aji-66	285	3	.	.	PUNCT
aji-66	286	1	2019;87(6	2019;87(6	NUM
aji-66	286	2	)	)	PUNCT
aji-66	286	3	.	.	PUNCT
aji-66	287	1	11	11	NUM
aji-66	287	2	.	.	PUNCT
aji-66	288	1	carter	carter	PROPN
aji-66	288	2	r	r	PROPN
aji-66	288	3	,	,	PUNCT
aji-66	288	4	stowers	stowers	PROPN
aji-66	288	5	a.	a.	PROPN
aji-66	288	6	current	current	ADJ
aji-66	288	7	developments	development	NOUN
aji-66	288	8	in	in	ADP
aji-66	288	9	malaria	malaria	NOUN
aji-66	288	10	transmissionblocking	transmissionblocke	VERB
aji-66	288	11	vaccines	vaccine	NOUN
aji-66	288	12	.	.	PUNCT
aji-66	289	1	expert	expert	NOUN
aji-66	289	2	opin	opin	NOUN
aji-66	289	3	biol	biol	NOUN
aji-66	289	4	ther	ther	ADV
aji-66	289	5	.	.	PUNCT
aji-66	290	1	2001;1(4):619–28	2001;1(4):619–28	NUM
aji-66	290	2	.	.	NOUN
aji-66	290	3	12	12	NUM
aji-66	290	4	.	.	PUNCT
aji-66	290	5	ariey	ariey	PROPN
aji-66	290	6	f	f	PROPN
aji-66	290	7	,	,	PUNCT
aji-66	291	1	hommel	hommel	PROPN
aji-66	291	2	d	d	PROPN
aji-66	291	3	,	,	PUNCT
aji-66	291	4	le	le	PROPN
aji-66	291	5	scanf	scanf	PROPN
aji-66	291	6	c	c	PROPN
aji-66	291	7	,	,	PUNCT
aji-66	291	8	duchemin	duchemin	PROPN
aji-66	291	9	jb	jb	PROPN
aji-66	291	10	,	,	PUNCT
aji-66	291	11	peneau	peneau	PROPN
aji-66	291	12	c	c	PROPN
aji-66	291	13	,	,	PUNCT
aji-66	291	14	hulin	hulin	PROPN
aji-66	291	15	a	a	PROPN
aji-66	291	16	,	,	PUNCT
aji-66	291	17	et	et	PROPN
aji-66	291	18	al	al	PROPN
aji-66	291	19	.	.	PROPN
aji-66	292	1	association	association	PROPN
aji-66	292	2	of	of	ADP
aji-66	292	3	severe	severe	ADJ
aji-66	292	4	malaria	malaria	NOUN
aji-66	292	5	with	with	ADP
aji-66	292	6	a	a	DET
aji-66	292	7	specific	specific	ADJ
aji-66	292	8	plasmodium	plasmodium	NOUN
aji-66	292	9	falciparum	falciparum	ADJ
aji-66	292	10	genotype	genotype	NOUN
aji-66	292	11	in	in	ADP
aji-66	292	12	french	french	ADJ
aji-66	292	13	guiana	guiana	PROPN
aji-66	292	14	.	.	PUNCT
aji-66	293	1	j	j	PROPN
aji-66	293	2	infect	infect	VERB
aji-66	293	3	dis	dis	PROPN
aji-66	293	4	.	.	PUNCT
aji-66	294	1	2001;184(2):237–41	2001;184(2):237–41	NUM
aji-66	294	2	.	.	NOUN
aji-66	295	1	13	13	NUM
aji-66	295	2	.	.	PUNCT
aji-66	296	1	ribacke	ribacke	PROPN
aji-66	296	2	u	u	PROPN
aji-66	296	3	,	,	PUNCT
aji-66	296	4	mok	mok	PROPN
aji-66	296	5	bw	bw	PROPN
aji-66	296	6	,	,	PUNCT
aji-66	296	7	wirta	wirta	VERB
aji-66	296	8	v	v	ADP
aji-66	296	9	,	,	PUNCT
aji-66	296	10	normark	normark	PROPN
aji-66	296	11	j	j	PROPN
aji-66	296	12	,	,	PUNCT
aji-66	296	13	lundeberg	lundeberg	PROPN
aji-66	296	14	j	j	PROPN
aji-66	296	15	,	,	PUNCT
aji-66	296	16	kironde	kironde	PROPN
aji-66	296	17	f	f	PROPN
aji-66	296	18	,	,	PUNCT
aji-66	296	19	et	et	PROPN
aji-66	296	20	al	al	PROPN
aji-66	296	21	.	.	PUNCT
aji-66	296	22	genome	genome	NOUN
aji-66	296	23	wide	wide	ADJ
aji-66	296	24	gene	gene	NOUN
aji-66	296	25	amplifications	amplification	NOUN
aji-66	296	26	and	and	CCONJ
aji-66	296	27	deletions	deletion	NOUN
aji-66	296	28	in	in	ADP
aji-66	296	29	plasmodium	plasmodium	NOUN
aji-66	296	30	falciparum	falciparum	NOUN
aji-66	296	31	.	.	PUNCT
aji-66	297	1	mol	mol	ADP
aji-66	297	2	biochem	biochem	PROPN
aji-66	297	3	parasitol	parasitol	NOUN
aji-66	297	4	.	.	PUNCT
aji-66	298	1	2007;155(1):33–44	2007;155(1):33–44	X
aji-66	298	2	.	.	PROPN
aji-66	298	3	14	14	NUM
aji-66	298	4	.	.	PUNCT
aji-66	299	1	gupta	gupta	PROPN
aji-66	299	2	s	s	PROPN
aji-66	299	3	,	,	PUNCT
aji-66	299	4	hill	hill	PROPN
aji-66	299	5	av	av	PROPN
aji-66	299	6	,	,	PUNCT
aji-66	299	7	kwiatkowski	kwiatkowski	VERB
aji-66	299	8	d	d	PROPN
aji-66	299	9	,	,	PUNCT
aji-66	299	10	greenwood	greenwood	PROPN
aji-66	299	11	am	am	PROPN
aji-66	299	12	,	,	PUNCT
aji-66	299	13	greenwood	greenwood	PROPN
aji-66	299	14	bm	bm	PROPN
aji-66	299	15	,	,	PUNCT
aji-66	299	16	day	day	NOUN
aji-66	299	17	kp	kp	INTJ
aji-66	299	18	.	.	PROPN
aji-66	300	1	parasite	parasite	ADJ
aji-66	300	2	virulence	virulence	NOUN
aji-66	300	3	and	and	CCONJ
aji-66	300	4	disease	disease	NOUN
aji-66	300	5	patterns	pattern	NOUN
aji-66	300	6	in	in	ADP
aji-66	300	7	plasmodium	plasmodium	NOUN
aji-66	300	8	falciparum	falciparum	NOUN
aji-66	300	9	malaria	malaria	NOUN
aji-66	300	10	.	.	PUNCT
aji-66	301	1	proc	proc	PROPN
aji-66	301	2	natl	natl	PROPN
aji-66	301	3	acad	acad	PROPN
aji-66	301	4	sci	sci	PROPN
aji-66	301	5	.	.	PUNCT
aji-66	302	1	1994;91(9):3715–9	1994;91(9):3715–9	NUM
aji-66	302	2	.	.	PUNCT
aji-66	303	1	15	15	NUM
aji-66	303	2	.	.	PUNCT
aji-66	304	1	carter	carter	PROPN
aji-66	304	2	r	r	PROPN
aji-66	304	3	,	,	PUNCT
aji-66	304	4	kumar	kumar	PROPN
aji-66	304	5	n	n	NUM
aji-66	304	6	,	,	PUNCT
aji-66	304	7	quakyi	quakyi	PROPN
aji-66	304	8	i	i	PROPN
aji-66	304	9	,	,	PUNCT
aji-66	304	10	good	good	PROPN
aji-66	304	11	m	m	PROPN
aji-66	304	12	,	,	PUNCT
aji-66	304	13	mendis	mendis	PROPN
aji-66	304	14	k	k	PROPN
aji-66	304	15	,	,	PUNCT
aji-66	304	16	graves	grave	VERB
aji-66	304	17	p	p	PRON
aji-66	304	18	,	,	PUNCT
aji-66	304	19	et	et	PROPN
aji-66	304	20	al	al	PROPN
aji-66	304	21	.	.	PROPN
aji-66	305	1	immunity	immunity	NOUN
aji-66	305	2	to	to	ADP
aji-66	305	3	sexual	sexual	ADJ
aji-66	305	4	stages	stage	NOUN
aji-66	305	5	of	of	ADP
aji-66	305	6	malaria	malaria	NOUN
aji-66	305	7	parasites	parasite	NOUN
aji-66	305	8	.	.	PUNCT
aji-66	306	1	malar	malar	ADJ
aji-66	306	2	immunol	immunol	NOUN
aji-66	306	3	.	.	PUNCT
aji-66	307	1	1988;41:193–214	1988;41:193–214	NUM
aji-66	307	2	.	.	PUNCT
aji-66	308	1	16	16	NUM
aji-66	308	2	.	.	PUNCT
aji-66	308	3	kiyuka	kiyuka	PROPN
aji-66	308	4	pk	pk	PROPN
aji-66	308	5	,	,	PUNCT
aji-66	308	6	meri	meri	PROPN
aji-66	308	7	s	s	PROPN
aji-66	308	8	,	,	PUNCT
aji-66	308	9	khattab	khattab	NOUN
aji-66	308	10	a.	a.	NOUN
aji-66	308	11	complement	complement	NOUN
aji-66	308	12	in	in	ADP
aji-66	308	13	malaria	malaria	NOUN
aji-66	308	14	:	:	PUNCT
aji-66	308	15	immune	immune	ADJ
aji-66	308	16	evasion	evasion	NOUN
aji-66	308	17	strategies	strategy	NOUN
aji-66	308	18	and	and	CCONJ
aji-66	308	19	role	role	NOUN
aji-66	308	20	in	in	ADP
aji-66	308	21	protective	protective	ADJ
aji-66	308	22	immunity	immunity	NOUN
aji-66	308	23	.	.	PUNCT
aji-66	309	1	febs	febs	PROPN
aji-66	309	2	lett	lett	PROPN
aji-66	309	3	.	.	PUNCT
aji-66	310	1	2020;594(16):2502–17	2020;594(16):2502–17	NUM
aji-66	310	2	.	.	PUNCT
aji-66	311	1	17	17	NUM
aji-66	311	2	.	.	PUNCT
aji-66	311	3	bousema	bousema	PROPN
aji-66	311	4	jt	jt	PROPN
aji-66	311	5	,	,	PUNCT
aji-66	311	6	drakeley	drakeley	PROPN
aji-66	311	7	cj	cj	PROPN
aji-66	311	8	,	,	PUNCT
aji-66	311	9	sauerwein	sauerwein	PROPN
aji-66	311	10	rw	rw	PROPN
aji-66	311	11	.	.	PUNCT
aji-66	311	12	sexual	sexual	ADJ
aji-66	311	13	-	-	PUNCT
aji-66	311	14	stage	stage	NOUN
aji-66	311	15	antibody	antibody	NOUN
aji-66	311	16	responses	response	NOUN
aji-66	311	17	to	to	ADP
aji-66	311	18	p.	p.	NOUN
aji-66	311	19	falciparum	falciparum	NOUN
aji-66	311	20	in	in	ADP
aji-66	311	21	endemic	endemic	ADJ
aji-66	311	22	populations	population	NOUN
aji-66	311	23	.	.	PUNCT
aji-66	312	1	curr	curr	PROPN
aji-66	312	2	mol	mol	ADP
aji-66	312	3	med	med	PROPN
aji-66	312	4	.	.	PUNCT
aji-66	313	1	2006;6(2):223–9	2006;6(2):223–9	NUM
aji-66	313	2	.	.	PUNCT
aji-66	314	1	18	18	NUM
aji-66	314	2	.	.	PUNCT
aji-66	314	3	pradel	pradel	NOUN
aji-66	314	4	g.	g.	PROPN
aji-66	314	5	proteins	protein	NOUN
aji-66	314	6	of	of	ADP
aji-66	314	7	the	the	DET
aji-66	314	8	malaria	malaria	NOUN
aji-66	314	9	parasite	parasite	VERB
aji-66	314	10	sexual	sexual	ADJ
aji-66	314	11	stages	stage	NOUN
aji-66	314	12	:	:	PUNCT
aji-66	314	13	expression	expression	NOUN
aji-66	314	14	,	,	PUNCT
aji-66	314	15	function	function	NOUN
aji-66	314	16	and	and	CCONJ
aji-66	314	17	potential	potential	NOUN
aji-66	314	18	for	for	ADP
aji-66	314	19	transmission	transmission	NOUN
aji-66	314	20	blocking	blocking	NOUN
aji-66	314	21	strategies	strategy	NOUN
aji-66	314	22	.	.	PUNCT
aji-66	315	1	parasitology	parasitology	NOUN
aji-66	315	2	.	.	PUNCT
aji-66	316	1	2007	2007	NUM
aji-66	316	2	;	;	PUNCT
aji-66	317	1	134(14):1911	134(14):1911	X
aji-66	317	2	.	.	PROPN
aji-66	317	3	19	19	NUM
aji-66	317	4	.	.	PUNCT
aji-66	317	5	world	world	PROPN
aji-66	317	6	health	health	PROPN
aji-66	317	7	organization	organization	PROPN
aji-66	317	8	.	.	PUNCT
aji-66	318	1	population	population	NOUN
aji-66	318	2	mobility	mobility	NOUN
aji-66	318	3	and	and	CCONJ
aji-66	318	4	malaria	malaria	NOUN
aji-66	318	5	;	;	PUNCT
aji-66	318	6	2017	2017	NUM
aji-66	318	7	.	.	PUNCT
aji-66	319	1	20	20	NUM
aji-66	319	2	.	.	PUNCT
aji-66	320	1	van	van	PROPN
aji-66	320	2	den	den	PROPN
aji-66	320	3	berg	berg	PROPN
aji-66	320	4	m	m	PROPN
aji-66	320	5	,	,	PUNCT
aji-66	320	6	ogutu	ogutu	PROPN
aji-66	320	7	b	b	NOUN
aji-66	320	8	,	,	PUNCT
aji-66	320	9	sewankambo	sewankambo	PROPN
aji-66	320	10	nk	nk	PROPN
aji-66	320	11	,	,	PUNCT
aji-66	320	12	biller	biller	NOUN
aji-66	320	13	-	-	PUNCT
aji-66	320	14	andorno	andorno	NOUN
aji-66	320	15	n	n	CCONJ
aji-66	320	16	,	,	PUNCT
aji-66	320	17	tanner	tanner	NOUN
aji-66	320	18	m.	m.	NOUN
aji-66	320	19	rts	rt	NOUN
aji-66	320	20	,	,	PUNCT
aji-66	320	21	s	s	PART
aji-66	320	22	malaria	malaria	NOUN
aji-66	320	23	vaccine	vaccine	NOUN
aji-66	320	24	pilot	pilot	NOUN
aji-66	320	25	studies	study	NOUN
aji-66	320	26	:	:	PUNCT
aji-66	320	27	addressing	address	VERB
aji-66	320	28	the	the	DET
aji-66	320	29	human	human	ADJ
aji-66	320	30	realities	reality	NOUN
aji-66	320	31	in	in	ADP
aji-66	320	32	large	large	ADJ
aji-66	320	33	-	-	PUNCT
aji-66	320	34	scale	scale	NOUN
aji-66	320	35	clinical	clinical	ADJ
aji-66	320	36	trials	trial	NOUN
aji-66	320	37	.	.	PUNCT
aji-66	321	1	trials	trial	NOUN
aji-66	321	2	.	.	PUNCT
aji-66	322	1	2019;20(1):1–4	2019;20(1):1–4	NOUN
aji-66	322	2	.	.	PUNCT
aji-66	323	1	21	21	NUM
aji-66	323	2	.	.	X
aji-66	323	3	dimala	dimala	PROPN
aji-66	323	4	ca	ca	PROPN
aji-66	323	5	,	,	PUNCT
aji-66	323	6	kika	kika	PROPN
aji-66	323	7	bt	bt	PROPN
aji-66	323	8	,	,	PUNCT
aji-66	323	9	kadia	kadia	PROPN
aji-66	323	10	bm	bm	PROPN
aji-66	323	11	,	,	PUNCT
aji-66	323	12	blencowe	blencowe	PROPN
aji-66	323	13	h.	h.	PROPN
aji-66	323	14	current	current	ADJ
aji-66	323	15	challenges	challenge	NOUN
aji-66	323	16	and	and	CCONJ
aji-66	323	17	proposed	propose	VERB
aji-66	323	18	solutions	solution	NOUN
aji-66	323	19	to	to	ADP
aji-66	323	20	the	the	DET
aji-66	323	21	effective	effective	ADJ
aji-66	323	22	implementation	implementation	NOUN
aji-66	323	23	of	of	ADP
aji-66	323	24	the	the	DET
aji-66	323	25	rts	rt	NOUN
aji-66	323	26	,	,	PUNCT
aji-66	323	27	s	s	PROPN
aji-66	323	28	/	/	SYM
aji-66	323	29	as01	as01	PROPN
aji-66	323	30	malaria	malaria	NOUN
aji-66	323	31	vaccine	vaccine	NOUN
aji-66	323	32	program	program	NOUN
aji-66	323	33	in	in	ADP
aji-66	323	34	sub	sub	ADJ
aji-66	323	35	-	-	ADJ
aji-66	323	36	saharan	saharan	ADJ
aji-66	323	37	africa	africa	PROPN
aji-66	323	38	:	:	PUNCT
aji-66	323	39	a	a	DET
aji-66	323	40	systematic	systematic	ADJ
aji-66	323	41	review	review	NOUN
aji-66	323	42	.	.	PUNCT
aji-66	324	1	plos	plos	PROPN
aji-66	324	2	one	one	NUM
aji-66	324	3	.	.	PUNCT
aji-66	325	1	2018;13(12):e0209744	2018;13(12):e0209744	NUM
aji-66	325	2	.	.	PUNCT
aji-66	326	1	22	22	NUM
aji-66	326	2	.	.	PUNCT
aji-66	327	1	doumbo	doumbo	PROPN
aji-66	327	2	ok	ok	PROPN
aji-66	327	3	,	,	PUNCT
aji-66	327	4	niaré	niaré	PROPN
aji-66	327	5	k	k	PROPN
aji-66	327	6	,	,	PUNCT
aji-66	327	7	healy	healy	PROPN
aji-66	327	8	sa	sa	PROPN
aji-66	327	9	,	,	PUNCT
aji-66	327	10	sagara	sagara	PROPN
aji-66	327	11	i	i	PROPN
aji-66	327	12	,	,	PUNCT
aji-66	328	1	duffy	duffy	PROPN
aji-66	328	2	pe	pe	PROPN
aji-66	328	3	.	.	PUNCT
aji-66	329	1	malaria	malaria	NOUN
aji-66	329	2	transmission	transmission	NOUN
aji-66	329	3	-	-	PUNCT
aji-66	329	4	blocking	block	VERB
aji-66	329	5	vaccines	vaccine	NOUN
aji-66	329	6	:	:	PUNCT
aji-66	329	7	present	present	ADJ
aji-66	329	8	status	status	NOUN
aji-66	329	9	and	and	CCONJ
aji-66	329	10	future	future	ADJ
aji-66	329	11	perspectives	perspective	NOUN
aji-66	329	12	.	.	PUNCT
aji-66	330	1	malar	malar	ADJ
aji-66	330	2	eliminleap	eliminleap	PROPN
aji-66	330	3	forward	forward	PROPN
aji-66	330	4	sylvie	sylvie	PROPN
aji-66	330	5	manguin	manguin	PROPN
aji-66	330	6	and	and	CCONJ
aji-66	330	7	vas	vas	X
aji-66	330	8	dev	dev	PROPN
aji-66	330	9	,	,	PUNCT
aji-66	330	10	intechopen	intechopen	ADJ
aji-66	330	11	;	;	PUNCT
aji-66	330	12	2018	2018	NUM
aji-66	330	13	.	.	PUNCT
aji-66	331	1	doi	doi	NOUN
aji-66	331	2	:	:	PUNCT
aji-66	331	3	10.5772	10.5772	NUM
aji-66	331	4	/	/	SYM
aji-66	331	5	intechopen.77241	intechopen.77241	PROPN
aji-66	331	6	23	23	NUM
aji-66	331	7	.	.	PUNCT
aji-66	332	1	shimp	shimp	PROPN
aji-66	332	2	jr	jr	PROPN
aji-66	332	3	rl	rl	PROPN
aji-66	332	4	,	,	PUNCT
aji-66	332	5	rowe	rowe	PROPN
aji-66	332	6	c	c	PROPN
aji-66	332	7	,	,	PUNCT
aji-66	332	8	reiter	reiter	PROPN
aji-66	332	9	k	k	PROPN
aji-66	332	10	,	,	PUNCT
aji-66	332	11	chen	chen	PROPN
aji-66	332	12	b	b	PROPN
aji-66	332	13	,	,	PUNCT
aji-66	332	14	nguyen	nguyen	NOUN
aji-66	332	15	v	v	NOUN
aji-66	332	16	,	,	PUNCT
aji-66	332	17	aebig	aebig	PROPN
aji-66	332	18	j	j	PROPN
aji-66	332	19	,	,	PUNCT
aji-66	332	20	et	et	PROPN
aji-66	332	21	al	al	PROPN
aji-66	332	22	.	.	PUNCT
aji-66	333	1	development	development	NOUN
aji-66	333	2	of	of	ADP
aji-66	333	3	a	a	DET
aji-66	333	4	pfs25	pfs25	PROPN
aji-66	333	5	-	-	PUNCT
aji-66	333	6	epa	epa	PROPN
aji-66	333	7	malaria	malaria	NOUN
aji-66	333	8	transmission	transmission	NOUN
aji-66	333	9	blocking	block	VERB
aji-66	333	10	vaccine	vaccine	NOUN
aji-66	333	11	as	as	ADP
aji-66	333	12	a	a	DET
aji-66	333	13	chemically	chemically	ADV
aji-66	333	14	conjugated	conjugate	VERB
aji-66	333	15	nanoparticle	nanoparticle	NOUN
aji-66	333	16	.	.	PUNCT
aji-66	334	1	vaccine	vaccine	NOUN
aji-66	334	2	.	.	PUNCT
aji-66	335	1	2013;31(28):2954	2013;31(28):2954	NUM
aji-66	335	2	–	–	PUNCT
aji-66	335	3	62	62	NUM
aji-66	335	4	.	.	X
aji-66	336	1	24	24	NUM
aji-66	336	2	.	.	PUNCT
aji-66	337	1	singh	singh	PROPN
aji-66	337	2	k	k	PROPN
aji-66	337	3	,	,	PUNCT
aji-66	337	4	burkhardt	burkhardt	PROPN
aji-66	337	5	m	m	PROPN
aji-66	337	6	,	,	PUNCT
aji-66	337	7	nakuchima	nakuchima	PROPN
aji-66	337	8	s	s	PROPN
aji-66	337	9	,	,	PUNCT
aji-66	337	10	herrera	herrera	PROPN
aji-66	337	11	r	r	NOUN
aji-66	337	12	,	,	PUNCT
aji-66	337	13	muratova	muratova	PROPN
aji-66	337	14	o	o	NOUN
aji-66	337	15	,	,	PUNCT
aji-66	337	16	gittis	gittis	PROPN
aji-66	337	17	ag	ag	PROPN
aji-66	337	18	,	,	PUNCT
aji-66	337	19	et	et	PROPN
aji-66	337	20	al	al	PROPN
aji-66	337	21	.	.	PROPN
aji-66	337	22	structure	structure	NOUN
aji-66	337	23	and	and	CCONJ
aji-66	337	24	function	function	NOUN
aji-66	337	25	of	of	ADP
aji-66	337	26	a	a	DET
aji-66	337	27	malaria	malaria	NOUN
aji-66	337	28	transmission	transmission	NOUN
aji-66	337	29	blocking	blocking	NOUN
aji-66	337	30	vaccine	vaccine	NOUN
aji-66	337	31	targeting	target	VERB
aji-66	337	32	pfs230	pfs230	PROPN
aji-66	337	33	and	and	CCONJ
aji-66	337	34	pfs230	pfs230	VERB
aji-66	337	35	-	-	PUNCT
aji-66	337	36	pfs48/45	pfs48/45	NOUN
aji-66	337	37	proteins	protein	NOUN
aji-66	337	38	.	.	PUNCT
aji-66	338	1	commun	commun	PROPN
aji-66	338	2	biol	biol	PROPN
aji-66	338	3	.	.	PUNCT
aji-66	339	1	2020;3(1):1–12	2020;3(1):1–12	NUM
aji-66	339	2	.	.	X
aji-66	340	1	25	25	NUM
aji-66	340	2	.	.	PUNCT
aji-66	341	1	lee	lee	PROPN
aji-66	341	2	sm	sm	PROPN
aji-66	341	3	,	,	PUNCT
aji-66	341	4	wu	wu	PROPN
aji-66	341	5	y	y	PROPN
aji-66	341	6	,	,	PUNCT
aji-66	341	7	hickey	hickey	PROPN
aji-66	341	8	jm	jm	PROPN
aji-66	341	9	,	,	PUNCT
aji-66	341	10	miura	miura	PROPN
aji-66	341	11	k	k	PROPN
aji-66	341	12	,	,	PUNCT
aji-66	341	13	whitaker	whitaker	PROPN
aji-66	341	14	n	n	PROPN
aji-66	341	15	,	,	PUNCT
aji-66	341	16	joshi	joshi	PROPN
aji-66	341	17	sb	sb	PROPN
aji-66	341	18	,	,	PUNCT
aji-66	341	19	et	et	PROPN
aji-66	341	20	al	al	PROPN
aji-66	341	21	.	.	PUNCT
aji-66	342	1	the	the	DET
aji-66	342	2	pfs230	pfs230	PROPN
aji-66	342	3	nterminal	nterminal	ADJ
aji-66	342	4	fragment	fragment	NOUN
aji-66	342	5	,	,	PUNCT
aji-66	342	6	pfs230d1	pfs230d1	NOUN
aji-66	342	7	+	+	NOUN
aji-66	342	8	:	:	PUNCT
aji-66	342	9	expression	expression	NOUN
aji-66	342	10	and	and	CCONJ
aji-66	342	11	characterization	characterization	NOUN
aji-66	342	12	of	of	ADP
aji-66	342	13	a	a	DET
aji-66	342	14	potential	potential	ADJ
aji-66	342	15	malaria	malaria	NOUN
aji-66	342	16	transmission	transmission	NOUN
aji-66	342	17	-	-	PUNCT
aji-66	342	18	blocking	block	VERB
aji-66	342	19	vaccine	vaccine	NOUN
aji-66	342	20	candidate	candidate	NOUN
aji-66	342	21	.	.	PUNCT
aji-66	343	1	malar	malar	ADJ
aji-66	343	2	j.	j.	PROPN
aji-66	343	3	2019;18(1):1–13	2019;18(1):1–13	PROPN
aji-66	343	4	.	.	PROPN
aji-66	344	1	26	26	NUM
aji-66	344	2	.	.	PUNCT
aji-66	345	1	delves	delf	NOUN
aji-66	345	2	mj	mj	PROPN
aji-66	345	3	,	,	PUNCT
aji-66	345	4	ramakrishnan	ramakrishnan	NOUN
aji-66	345	5	c	c	PROPN
aji-66	345	6	,	,	PUNCT
aji-66	345	7	blagborough	blagborough	PROPN
aji-66	345	8	am	am	PROPN
aji-66	345	9	,	,	PUNCT
aji-66	345	10	leroy	leroy	PROPN
aji-66	345	11	d	d	PROPN
aji-66	345	12	,	,	PUNCT
aji-66	345	13	wells	wells	PROPN
aji-66	345	14	tn	tn	PROPN
aji-66	345	15	,	,	PUNCT
aji-66	345	16	sinden	sinden	PROPN
aji-66	345	17	re	re	PROPN
aji-66	345	18	.	.	PUNCT
aji-66	346	1	a	a	DET
aji-66	346	2	high	high	ADJ
aji-66	346	3	-	-	PUNCT
aji-66	346	4	throughput	throughput	NOUN
aji-66	346	5	assay	assay	NOUN
aji-66	346	6	for	for	ADP
aji-66	346	7	the	the	DET
aji-66	346	8	identification	identification	NOUN
aji-66	346	9	of	of	ADP
aji-66	346	10	malarial	malarial	ADJ
aji-66	346	11	transmission	transmission	NOUN
aji-66	346	12	-	-	PUNCT
aji-66	346	13	blocking	block	VERB
aji-66	346	14	drugs	drug	NOUN
aji-66	346	15	and	and	CCONJ
aji-66	346	16	vaccines	vaccine	NOUN
aji-66	346	17	.	.	PUNCT
aji-66	347	1	int	int	NOUN
aji-66	347	2	j	j	PROPN
aji-66	347	3	parasitol	parasitol	NOUN
aji-66	347	4	.	.	PUNCT
aji-66	348	1	2012	2012	NUM
aji-66	348	2	;	;	PUNCT
aji-66	348	3	42(11):999–1006	42(11):999–1006	X
aji-66	348	4	.	.	PUNCT
aji-66	349	1	27	27	NUM
aji-66	349	2	.	.	PUNCT
aji-66	350	1	moore	moore	PROPN
aji-66	350	2	sa	sa	PROPN
aji-66	350	3	,	,	PUNCT
aji-66	350	4	surgey	surgey	PROPN
aji-66	350	5	eg	eg	PROPN
aji-66	350	6	,	,	PUNCT
aji-66	350	7	cadwgan	cadwgan	ADJ
aji-66	350	8	am	am	NOUN
aji-66	350	9	.	.	PUNCT
aji-66	351	1	malaria	malaria	NOUN
aji-66	351	2	vaccines	vaccine	NOUN
aji-66	351	3	:	:	PUNCT
aji-66	351	4	where	where	SCONJ
aji-66	351	5	are	be	AUX
aji-66	351	6	we	we	PRON
aji-66	351	7	and	and	CCONJ
aji-66	351	8	where	where	SCONJ
aji-66	351	9	are	be	AUX
aji-66	351	10	we	we	PRON
aji-66	351	11	going	go	VERB
aji-66	351	12	?	?	PUNCT
aji-66	352	1	lancet	lancet	PROPN
aji-66	352	2	infect	infect	PROPN
aji-66	352	3	dis	dis	PROPN
aji-66	352	4	.	.	PUNCT
aji-66	353	1	2002;2(12):737–43	2002;2(12):737–43	X
aji-66	353	2	.	.	PUNCT
aji-66	353	3	28	28	NUM
aji-66	353	4	.	.	PUNCT
aji-66	354	1	nikolaeva	nikolaeva	PROPN
aji-66	354	2	d	d	PROPN
aji-66	354	3	,	,	PUNCT
aji-66	354	4	draper	draper	NOUN
aji-66	354	5	sj	sj	PROPN
aji-66	354	6	,	,	PUNCT
aji-66	354	7	biswas	biswas	PROPN
aji-66	354	8	s.	s.	PROPN
aji-66	354	9	toward	toward	ADP
aji-66	354	10	the	the	DET
aji-66	354	11	development	development	NOUN
aji-66	354	12	of	of	ADP
aji-66	354	13	effective	effective	ADJ
aji-66	354	14	transmissionblocking	transmissionblocke	VERB
aji-66	354	15	vaccines	vaccine	NOUN
aji-66	354	16	for	for	ADP
aji-66	354	17	malaria	malaria	NOUN
aji-66	354	18	.	.	PUNCT
aji-66	355	1	expert	expert	NOUN
aji-66	355	2	rev	rev	VERB
aji-66	355	3	vaccines	vaccine	NOUN
aji-66	355	4	.	.	PUNCT
aji-66	356	1	2015;14(5	2015;14(5	NUM
aji-66	356	2	):	):	PUNCT
aji-66	356	3	653–80	653–80	NUM
aji-66	356	4	.	.	PROPN
aji-66	357	1	29	29	NUM
aji-66	357	2	.	.	PUNCT
aji-66	357	3	sauerwein	sauerwein	PROPN
aji-66	357	4	rw	rw	PROPN
aji-66	357	5	,	,	PUNCT
aji-66	357	6	bousema	bousema	NOUN
aji-66	357	7	t.	t.	NOUN
aji-66	357	8	transmission	transmission	NOUN
aji-66	357	9	blocking	block	VERB
aji-66	357	10	malaria	malaria	NOUN
aji-66	357	11	vaccines	vaccine	NOUN
aji-66	357	12	:	:	PUNCT
aji-66	357	13	assays	assay	NOUN
aji-66	357	14	and	and	CCONJ
aji-66	357	15	candidates	candidate	NOUN
aji-66	357	16	in	in	ADP
aji-66	357	17	clinical	clinical	ADJ
aji-66	357	18	development	development	NOUN
aji-66	357	19	.	.	PUNCT
aji-66	358	1	vaccine	vaccine	NOUN
aji-66	358	2	.	.	PUNCT
aji-66	359	1	2015;33(52):7476–82	2015;33(52):7476–82	NUM
aji-66	359	2	.	.	NOUN
aji-66	359	3	30	30	NUM
aji-66	359	4	.	.	PUNCT
aji-66	360	1	kaslow	kaslow	PROPN
aji-66	360	2	dc	dc	PROPN
aji-66	360	3	,	,	PUNCT
aji-66	360	4	shiloach	shiloach	ADV
aji-66	360	5	j.	j.	PROPN
aji-66	360	6	production	production	PROPN
aji-66	360	7	,	,	PUNCT
aji-66	360	8	purification	purification	NOUN
aji-66	360	9	and	and	CCONJ
aji-66	360	10	immunogenicity	immunogenicity	NOUN
aji-66	360	11	of	of	ADP
aji-66	360	12	a	a	DET
aji-66	360	13	malaria	malaria	NOUN
aji-66	360	14	transmission	transmission	NOUN
aji-66	360	15	-	-	PUNCT
aji-66	360	16	blocking	block	VERB
aji-66	360	17	vaccine	vaccine	NOUN
aji-66	360	18	candidate	candidate	NOUN
aji-66	360	19	:	:	PUNCT
aji-66	360	20	tbv25h	tbv25h	NOUN
aji-66	360	21	expressed	express	VERB
aji-66	360	22	in	in	ADP
aji-66	360	23	yeast	yeast	NOUN
aji-66	360	24	and	and	CCONJ
aji-66	360	25	purified	purified	ADJ
aji-66	360	26	using	use	VERB
aji-66	360	27	nickel	nickel	NOUN
aji-66	360	28	-	-	PUNCT
aji-66	360	29	nta	nta	NOUN
aji-66	360	30	agarose	agarose	NOUN
aji-66	360	31	.	.	PUNCT
aji-66	361	1	bio	bio	PROPN
aji-66	361	2	/	/	SYM
aji-66	361	3	technology	technology	NOUN
aji-66	361	4	.	.	PUNCT
aji-66	362	1	1994;12(5):494–9	1994;12(5):494–9	NUM
aji-66	362	2	.	.	PUNCT
aji-66	363	1	31	31	NUM
aji-66	363	2	.	.	PUNCT
aji-66	364	1	delves	delves	PROPN
aji-66	364	2	mj	mj	PROPN
aji-66	364	3	,	,	PUNCT
aji-66	364	4	sinden	sinden	PROPN
aji-66	364	5	re	re	PROPN
aji-66	364	6	.	.	PUNCT
aji-66	365	1	a	a	DET
aji-66	365	2	semi	semi	ADJ
aji-66	365	3	-	-	ADJ
aji-66	365	4	automated	automated	ADJ
aji-66	365	5	method	method	NOUN
aji-66	365	6	for	for	ADP
aji-66	365	7	counting	count	VERB
aji-66	365	8	fluorescent	fluorescent	ADJ
aji-66	365	9	malaria	malaria	NOUN
aji-66	365	10	oocysts	oocyst	NOUN
aji-66	365	11	increases	increase	VERB
aji-66	365	12	the	the	DET
aji-66	365	13	throughput	throughput	NOUN
aji-66	365	14	of	of	ADP
aji-66	365	15	transmission	transmission	NOUN
aji-66	365	16	blocking	block	VERB
aji-66	365	17	studies	study	NOUN
aji-66	365	18	.	.	PUNCT
aji-66	366	1	malar	malar	ADJ
aji-66	366	2	j.	j.	PROPN
aji-66	366	3	2010;9(1):1–8	2010;9(1):1–8	NUM
aji-66	366	4	.	.	PUNCT
aji-66	366	5	32	32	NUM
aji-66	366	6	.	.	PUNCT
aji-66	366	7	takala	takala	PROPN
aji-66	366	8	sl	sl	PROPN
aji-66	366	9	,	,	PUNCT
aji-66	366	10	plowe	plowe	PROPN
aji-66	366	11	cv	cv	PROPN
aji-66	366	12	.	.	PUNCT
aji-66	366	13	genetic	genetic	ADJ
aji-66	366	14	diversity	diversity	NOUN
aji-66	366	15	and	and	CCONJ
aji-66	366	16	malaria	malaria	NOUN
aji-66	366	17	vaccine	vaccine	NOUN
aji-66	366	18	design	design	NOUN
aji-66	366	19	,	,	PUNCT
aji-66	366	20	testing	testing	NOUN
aji-66	366	21	and	and	CCONJ
aji-66	366	22	efficacy	efficacy	NOUN
aji-66	366	23	:	:	PUNCT
aji-66	366	24	preventing	prevent	VERB
aji-66	366	25	and	and	CCONJ
aji-66	366	26	overcoming	overcome	VERB
aji-66	366	27	wangai	wangai	NOUN
aji-66	366	28	et	et	PROPN
aji-66	366	29	al	al	PROPN
aji-66	366	30	.	.	PROPN
aji-66	366	31	;	;	PUNCT
aji-66	366	32	aji	aji	PROPN
aji-66	366	33	,	,	PUNCT
aji-66	366	34	4(1	4(1	NOUN
aji-66	366	35	):	):	PUNCT
aji-66	366	36	77	77	NUM
aji-66	366	37	-	-	SYM
aji-66	366	38	84	84	NUM
aji-66	366	39	,	,	PUNCT
aji-66	366	40	2021	2021	NUM
aji-66	366	41	;	;	PUNCT
aji-66	366	42	article	article	NOUN
aji-66	366	43	no.aji.69854	no.aji.69854	NOUN
aji-66	366	44	84	84	NUM
aji-66	366	45	‘	'	PUNCT
aji-66	366	46	vaccine	vaccine	NOUN
aji-66	366	47	resistant	resistant	ADJ
aji-66	366	48	malaria	malaria	NOUN
aji-66	366	49	.	.	PUNCT
aji-66	366	50	’	'	PUNCT
aji-66	367	1	parasite	parasite	ADJ
aji-66	367	2	immunol	immunol	NOUN
aji-66	367	3	.	.	PUNCT
aji-66	368	1	2009;31(9):560–73	2009;31(9):560–73	NUM
aji-66	368	2	.	.	PUNCT
aji-66	369	1	33	33	NUM
aji-66	369	2	.	.	PUNCT
aji-66	370	1	scally	scally	PROPN
aji-66	370	2	sw	sw	PROPN
aji-66	370	3	,	,	PUNCT
aji-66	370	4	mcleod	mcleod	PROPN
aji-66	370	5	b	b	PROPN
aji-66	370	6	,	,	PUNCT
aji-66	370	7	bosch	bosch	PROPN
aji-66	370	8	a	a	PROPN
aji-66	370	9	,	,	PUNCT
aji-66	370	10	miura	miura	PROPN
aji-66	370	11	k	k	PROPN
aji-66	370	12	,	,	PUNCT
aji-66	370	13	liang	liang	PROPN
aji-66	370	14	q	q	PROPN
aji-66	370	15	,	,	PUNCT
aji-66	370	16	carroll	carroll	PROPN
aji-66	370	17	s	s	PROPN
aji-66	370	18	,	,	PUNCT
aji-66	370	19	et	et	PROPN
aji-66	370	20	al	al	PROPN
aji-66	370	21	.	.	PUNCT
aji-66	371	1	molecular	molecular	ADJ
aji-66	371	2	definition	definition	NOUN
aji-66	371	3	of	of	ADP
aji-66	371	4	multiple	multiple	ADJ
aji-66	371	5	sites	site	NOUN
aji-66	371	6	of	of	ADP
aji-66	371	7	antibody	antibody	NOUN
aji-66	371	8	inhibition	inhibition	NOUN
aji-66	371	9	of	of	ADP
aji-66	371	10	malaria	malaria	NOUN
aji-66	371	11	transmission	transmission	NOUN
aji-66	371	12	-	-	PUNCT
aji-66	371	13	blocking	block	VERB
aji-66	371	14	vaccine	vaccine	NOUN
aji-66	371	15	antigen	antigen	PROPN
aji-66	371	16	pfs25	pfs25	PROPN
aji-66	371	17	.	.	PUNCT
aji-66	372	1	nat	nat	PROPN
aji-66	372	2	commun	commun	PROPN
aji-66	372	3	.	.	PUNCT
aji-66	373	1	2017;8(1):1–11	2017;8(1):1–11	NUM
aji-66	373	2	.	.	X
aji-66	373	3	34	34	NUM
aji-66	373	4	.	.	PUNCT
aji-66	373	5	jones	jones	PROPN
aji-66	373	6	rm	rm	PROPN
aji-66	373	7	,	,	PUNCT
aji-66	373	8	chichester	chichester	PROPN
aji-66	373	9	ja	ja	PROPN
aji-66	373	10	,	,	PUNCT
aji-66	373	11	mett	mett	PROPN
aji-66	373	12	v	v	PROPN
aji-66	373	13	,	,	PUNCT
aji-66	373	14	jaje	jaje	PROPN
aji-66	373	15	j	j	PROPN
aji-66	373	16	,	,	PUNCT
aji-66	373	17	tottey	tottey	PROPN
aji-66	373	18	s	s	PROPN
aji-66	373	19	,	,	PUNCT
aji-66	373	20	manceva	manceva	PROPN
aji-66	373	21	s	s	PROPN
aji-66	373	22	,	,	PUNCT
aji-66	373	23	et	et	PROPN
aji-66	373	24	al	al	PROPN
aji-66	373	25	.	.	PUNCT
aji-66	374	1	a	a	DET
aji-66	374	2	plantproduced	plantproduced	ADJ
aji-66	374	3	pfs25	pfs25	PROPN
aji-66	374	4	vlp	vlp	PROPN
aji-66	374	5	malaria	malaria	NOUN
aji-66	374	6	vaccine	vaccine	NOUN
aji-66	374	7	candidate	candidate	NOUN
aji-66	374	8	induces	induce	VERB
aji-66	374	9	persistent	persistent	ADJ
aji-66	374	10	transmission	transmission	NOUN
aji-66	374	11	blocking	blocking	NOUN
aji-66	374	12	antibodies	antibody	NOUN
aji-66	374	13	against	against	ADP
aji-66	374	14	plasmodium	plasmodium	NOUN
aji-66	374	15	falciparum	falciparum	NOUN
aji-66	374	16	in	in	ADP
aji-66	374	17	immunized	immunize	VERB
aji-66	374	18	mice	mouse	NOUN
aji-66	374	19	.	.	PUNCT
aji-66	375	1	plos	plos	PROPN
aji-66	375	2	one	one	NUM
aji-66	375	3	.	.	PUNCT
aji-66	376	1	2013;8(11):e79538	2013;8(11):e79538	NOUN
aji-66	376	2	.	.	PUNCT
aji-66	376	3	35	35	NUM
aji-66	376	4	.	.	PUNCT
aji-66	377	1	duffy	duffy	PROPN
aji-66	377	2	pe	pe	PROPN
aji-66	377	3	,	,	PUNCT
aji-66	377	4	kaslow	kaslow	PROPN
aji-66	377	5	dc	dc	PROPN
aji-66	377	6	.	.	PUNCT
aji-66	378	1	a	a	DET
aji-66	378	2	novel	novel	ADJ
aji-66	378	3	malaria	malaria	NOUN
aji-66	378	4	protein	protein	NOUN
aji-66	378	5	,	,	PUNCT
aji-66	378	6	pfs28	pfs28	NOUN
aji-66	378	7	,	,	PUNCT
aji-66	378	8	and	and	CCONJ
aji-66	378	9	pfs25	pfs25	NOUN
aji-66	378	10	are	be	AUX
aji-66	378	11	genetically	genetically	ADV
aji-66	378	12	linked	link	VERB
aji-66	378	13	and	and	CCONJ
aji-66	378	14	synergistic	synergistic	ADJ
aji-66	378	15	as	as	ADP
aji-66	378	16	falciparum	falciparum	ADJ
aji-66	378	17	malaria	malaria	NOUN
aji-66	378	18	transmission	transmission	NOUN
aji-66	378	19	-	-	PUNCT
aji-66	378	20	blocking	block	VERB
aji-66	378	21	vaccines	vaccine	NOUN
aji-66	378	22	.	.	PUNCT
aji-66	379	1	infect	infect	VERB
aji-66	379	2	immun	immun	PROPN
aji-66	379	3	.	.	PUNCT
aji-66	380	1	1997;65(3):1109–13	1997;65(3):1109–13	PROPN
aji-66	380	2	.	.	PUNCT
aji-66	381	1	36	36	NUM
aji-66	381	2	.	.	PUNCT
aji-66	382	1	kumar	kumar	PROPN
aji-66	382	2	r	r	PROPN
aji-66	382	3	,	,	PUNCT
aji-66	382	4	angov	angov	NOUN
aji-66	382	5	e	e	NOUN
aji-66	382	6	,	,	PUNCT
aji-66	382	7	kumar	kumar	PROPN
aji-66	382	8	n.	n.	PROPN
aji-66	382	9	potent	potent	PROPN
aji-66	382	10	malaria	malaria	NOUN
aji-66	382	11	transmission	transmission	NOUN
aji-66	382	12	-	-	PUNCT
aji-66	382	13	blocking	block	VERB
aji-66	382	14	antibody	antibody	NOUN
aji-66	382	15	responses	response	NOUN
aji-66	382	16	elicited	elicit	VERB
aji-66	382	17	by	by	ADP
aji-66	382	18	plasmodium	plasmodium	NOUN
aji-66	382	19	falciparum	falciparum	ADJ
aji-66	382	20	pfs25	pfs25	PROPN
aji-66	382	21	expressed	express	VERB
aji-66	382	22	in	in	ADP
aji-66	382	23	escherichia	escherichia	NOUN
aji-66	382	24	coli	coli	NOUN
aji-66	382	25	after	after	ADP
aji-66	382	26	successful	successful	ADJ
aji-66	382	27	protein	protein	NOUN
aji-66	382	28	refolding	refolding	NOUN
aji-66	382	29	.	.	PUNCT
aji-66	383	1	infect	infect	VERB
aji-66	383	2	immun	immun	PROPN
aji-66	383	3	.	.	PUNCT
aji-66	384	1	2014;82(4):1453–9	2014;82(4):1453–9	X
aji-66	384	2	.	.	PUNCT
aji-66	385	1	37	37	NUM
aji-66	385	2	.	.	PUNCT
aji-66	386	1	lee	lee	PROPN
aji-66	386	2	s	s	PROPN
aji-66	386	3	-	-	PROPN
aji-66	386	4	m	m	PROPN
aji-66	386	5	,	,	PUNCT
aji-66	386	6	plieskatt	plieskatt	PROPN
aji-66	386	7	j	j	PROPN
aji-66	386	8	,	,	PUNCT
aji-66	386	9	king	king	PROPN
aji-66	386	10	cr	cr	PROPN
aji-66	386	11	.	.	PROPN
aji-66	386	12	disulfide	disulfide	PROPN
aji-66	386	13	bond	bond	NOUN
aji-66	386	14	mapping	mapping	NOUN
aji-66	386	15	of	of	ADP
aji-66	386	16	pfs25	pfs25	PROPN
aji-66	386	17	,	,	PUNCT
aji-66	386	18	a	a	DET
aji-66	386	19	recombinant	recombinant	ADJ
aji-66	386	20	malaria	malaria	NOUN
aji-66	386	21	transmission	transmission	NOUN
aji-66	386	22	blocking	block	VERB
aji-66	386	23	vaccine	vaccine	NOUN
aji-66	386	24	candidate	candidate	NOUN
aji-66	386	25	.	.	PUNCT
aji-66	387	1	anal	anal	ADJ
aji-66	387	2	biochem	biochem	PROPN
aji-66	387	3	.	.	PUNCT
aji-66	388	1	2018;542	2018;542	NUM
aji-66	388	2	:	:	PUNCT
aji-66	389	1	20–3	20–3	NUM
aji-66	389	2	.	.	PUNCT
aji-66	390	1	38	38	NUM
aji-66	390	2	.	.	PUNCT
aji-66	391	1	lee	lee	PROPN
aji-66	391	2	sm	sm	PROPN
aji-66	391	3	,	,	PUNCT
aji-66	391	4	hickey	hickey	PROPN
aji-66	391	5	jm	jm	PROPN
aji-66	391	6	,	,	PUNCT
aji-66	391	7	miura	miura	PROPN
aji-66	391	8	k	k	PROPN
aji-66	391	9	,	,	PUNCT
aji-66	391	10	joshi	joshi	PROPN
aji-66	391	11	sb	sb	PROPN
aji-66	391	12	,	,	PUNCT
aji-66	391	13	volkin	volkin	PROPN
aji-66	391	14	db	db	PROPN
aji-66	391	15	,	,	PUNCT
aji-66	391	16	king	king	PROPN
aji-66	391	17	cr	cr	PROPN
aji-66	391	18	,	,	PUNCT
aji-66	391	19	et	et	PROPN
aji-66	391	20	al	al	PROPN
aji-66	391	21	.	.	PUNCT
aji-66	392	1	a	a	DET
aji-66	392	2	c	c	NOUN
aji-66	392	3	-	-	PUNCT
aji-66	392	4	terminal	terminal	ADJ
aji-66	392	5	pfs48/45	pfs48/45	NOUN
aji-66	392	6	malaria	malaria	NOUN
aji-66	392	7	transmission	transmission	NOUN
aji-66	392	8	-	-	PUNCT
aji-66	392	9	blocking	block	VERB
aji-66	392	10	vaccine	vaccine	NOUN
aji-66	392	11	candidate	candidate	NOUN
aji-66	392	12	produced	produce	VERB
aji-66	392	13	in	in	ADP
aji-66	392	14	the	the	DET
aji-66	392	15	baculovirus	baculovirus	NOUN
aji-66	392	16	expression	expression	NOUN
aji-66	392	17	system	system	NOUN
aji-66	392	18	.	.	PUNCT
aji-66	393	1	sci	sci	PROPN
aji-66	393	2	rep	rep	PROPN
aji-66	393	3	.	.	PROPN
aji-66	393	4	2020;10(1):1–14	2020;10(1):1–14	PROPN
aji-66	393	5	.	.	PROPN
aji-66	393	6	39	39	NUM
aji-66	393	7	.	.	PUNCT
aji-66	394	1	tsuboi	tsuboi	PROPN
aji-66	394	2	t	t	PROPN
aji-66	394	3	,	,	PUNCT
aji-66	394	4	takeo	takeo	PROPN
aji-66	394	5	s	s	PROPN
aji-66	394	6	,	,	PUNCT
aji-66	394	7	arumugam	arumugam	ADJ
aji-66	394	8	tu	tu	PROPN
aji-66	394	9	,	,	PUNCT
aji-66	394	10	otsuki	otsuki	ADJ
aji-66	394	11	h	h	NOUN
aji-66	394	12	,	,	PUNCT
aji-66	394	13	torii	torii	PROPN
aji-66	394	14	m.	m.	NOUN
aji-66	394	15	the	the	DET
aji-66	394	16	wheat	wheat	NOUN
aji-66	394	17	germ	germ	NOUN
aji-66	394	18	cell	cell	NOUN
aji-66	394	19	-	-	PUNCT
aji-66	394	20	free	free	ADJ
aji-66	394	21	protein	protein	NOUN
aji-66	394	22	synthesis	synthesis	NOUN
aji-66	394	23	system	system	NOUN
aji-66	394	24	:	:	PUNCT
aji-66	394	25	a	a	DET
aji-66	394	26	key	key	ADJ
aji-66	394	27	tool	tool	NOUN
aji-66	394	28	for	for	ADP
aji-66	394	29	novel	novel	ADJ
aji-66	394	30	malaria	malaria	NOUN
aji-66	394	31	vaccine	vaccine	NOUN
aji-66	394	32	candidate	candidate	NOUN
aji-66	394	33	discovery	discovery	NOUN
aji-66	394	34	.	.	PUNCT
aji-66	395	1	acta	acta	PROPN
aji-66	395	2	trop	trop	PROPN
aji-66	395	3	.	.	PUNCT
aji-66	395	4	2010;114(3	2010;114(3	NUM
aji-66	395	5	):	):	PUNCT
aji-66	395	6	171–6	171–6	NUM
aji-66	395	7	.	.	PUNCT
aji-66	396	1	40	40	NUM
aji-66	396	2	.	.	PUNCT
aji-66	397	1	huang	huang	PROPN
aji-66	397	2	w	w	PROPN
aji-66	397	3	-	-	PROPN
aji-66	397	4	c	c	PROPN
aji-66	397	5	,	,	PUNCT
aji-66	397	6	sia	sia	PROPN
aji-66	397	7	zr	zr	PROPN
aji-66	397	8	,	,	PUNCT
aji-66	397	9	lovell	lovell	PROPN
aji-66	397	10	jf	jf	PROPN
aji-66	397	11	.	.	PROPN
aji-66	397	12	adjuvant	adjuvant	PROPN
aji-66	397	13	and	and	CCONJ
aji-66	397	14	antigen	antigen	ADJ
aji-66	397	15	systems	system	NOUN
aji-66	397	16	for	for	ADP
aji-66	397	17	malaria	malaria	NOUN
aji-66	397	18	transmission	transmission	NOUN
aji-66	397	19	-	-	PUNCT
aji-66	397	20	blocking	block	VERB
aji-66	397	21	vaccines	vaccine	NOUN
aji-66	397	22	.	.	PUNCT
aji-66	398	1	adv	adv	PROPN
aji-66	398	2	biosyst	biosyst	PROPN
aji-66	398	3	.	.	PUNCT
aji-66	399	1	2018;2(10):1800011	2018;2(10):1800011	X
aji-66	399	2	.	.	NOUN
aji-66	399	3	41	41	NUM
aji-66	399	4	.	.	PUNCT
aji-66	400	1	huang	huang	PROPN
aji-66	400	2	w	w	PROPN
aji-66	400	3	-	-	PROPN
aji-66	400	4	c	c	PROPN
aji-66	400	5	,	,	PUNCT
aji-66	400	6	sia	sia	PROPN
aji-66	400	7	zr	zr	PROPN
aji-66	400	8	,	,	PUNCT
aji-66	400	9	lovell	lovell	PROPN
aji-66	400	10	jf	jf	PROPN
aji-66	400	11	.	.	PROPN
aji-66	400	12	adjuvant	adjuvant	PROPN
aji-66	400	13	and	and	CCONJ
aji-66	400	14	antigen	antigen	ADJ
aji-66	400	15	systems	system	NOUN
aji-66	400	16	for	for	ADP
aji-66	400	17	malaria	malaria	NOUN
aji-66	400	18	378	378	NUM
aji-66	400	19	transmission	transmission	NOUN
aji-66	400	20	-	-	PUNCT
aji-66	400	21	blocking	block	VERB
aji-66	400	22	vaccines	vaccine	NOUN
aji-66	400	23	.	.	PUNCT
aji-66	401	1	adv	adv	PROPN
aji-66	401	2	biosyst	biosyst	PROPN
aji-66	401	3	.	.	PUNCT
aji-66	402	1	2018;2(10):1800011	2018;2(10):1800011	X
aji-66	402	2	.	.	PUNCT
aji-66	403	1	42	42	NUM
aji-66	403	2	.	.	PUNCT
aji-66	404	1	draper	draper	NOUN
aji-66	404	2	sj	sj	PROPN
aji-66	404	3	,	,	PUNCT
aji-66	404	4	angov	angov	NOUN
aji-66	404	5	e	e	PROPN
aji-66	404	6	,	,	PUNCT
aji-66	404	7	horii	horii	PROPN
aji-66	404	8	t	t	PROPN
aji-66	404	9	,	,	PUNCT
aji-66	404	10	miller	miller	PROPN
aji-66	404	11	lh	lh	PROPN
aji-66	404	12	,	,	PUNCT
aji-66	404	13	srinivasan	srinivasan	PROPN
aji-66	404	14	p	p	PROPN
aji-66	404	15	,	,	PUNCT
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aji-66	404	19	et	et	PROPN
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aji-66	405	1	recent	recent	ADJ
aji-66	405	2	advances	advance	NOUN
aji-66	405	3	in	in	ADP
aji-66	405	4	recombinant	recombinant	ADJ
aji-66	405	5	protein	protein	NOUN
aji-66	405	6	-	-	PUNCT
aji-66	405	7	based	base	VERB
aji-66	405	8	malaria	malaria	NOUN
aji-66	405	9	vaccines	vaccine	NOUN
aji-66	405	10	.	.	PUNCT
aji-66	406	1	vaccine	vaccine	NOUN
aji-66	406	2	.	.	PUNCT
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aji-66	408	2	.	.	PUNCT
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aji-66	456	1	_	_	PUNCT
aji-66	457	1	_	_	PUNCT
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aji-66	482	1	_	_	PUNCT
aji-66	483	1	_	_	PUNCT
aji-66	484	1	_	_	PUNCT
aji-66	485	1	_	_	PUNCT
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aji-66	490	4	et	et	PROPN
aji-66	490	5	al	al	PROPN
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aji-66	490	9	is	be	AUX
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aji-66	490	12	access	access	NOUN
aji-66	490	13	article	article	NOUN
aji-66	490	14	distributed	distribute	VERB
aji-66	490	15	under	under	ADP
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aji-66	490	17	terms	term	NOUN
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aji-66	490	19	the	the	DET
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aji-66	490	22	attribution	attribution	NOUN
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aji-66	490	26	)	)	PUNCT
aji-66	490	27	,	,	PUNCT
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aji-66	490	32	,	,	PUNCT
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aji-66	490	34	,	,	PUNCT
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aji-66	490	36	reproduction	reproduction	NOUN
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aji-66	490	40	,	,	PUNCT
aji-66	490	41	provided	provide	VERB
aji-66	490	42	the	the	DET
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aji-66	491	1	peer	peer	NOUN
aji-66	491	2	-	-	PUNCT
aji-66	491	3	review	review	NOUN
aji-66	491	4	history	history	NOUN
aji-66	491	5	:	:	PUNCT
aji-66	491	6	the	the	DET
aji-66	491	7	peer	peer	NOUN
aji-66	491	8	review	review	NOUN
aji-66	491	9	history	history	NOUN
aji-66	491	10	for	for	ADP
aji-66	491	11	this	this	DET
aji-66	491	12	paper	paper	NOUN
aji-66	491	13	can	can	AUX
aji-66	491	14	be	be	AUX
aji-66	491	15	accessed	access	VERB
aji-66	491	16	here	here	ADV
aji-66	491	17	:	:	PUNCT
aji-66	491	18	https://www.sdiarticle4.com/review-history/69854	https://www.sdiarticle4.com/review-history/69854	PROPN
aji-66	491	19	http://creativecommons.org/licenses/by/4.0	http://creativecommons.org/licenses/by/4.0	X