id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjms-12604	Ahmad, Shamweel	Prevalence of Ciprofloxacin Resistance Among Gram-Negative Bacilli at a Specialist Hospital in Saudi Arabia	2012-11-13	5	.pdf	application/pdf	2646	187	53	Early researchers thought that fluoroquinolone resistance was unlikely to evolve, largely because resistant Escherichia coli mutants are exceptionally difficult to select in vitro 2 and because plasmid-mediated quinolone resistance remained unknown even after 30 years of nalidixic acid usage. quinolone resistance has emerged in E. coli and other Enterobacteriaceae, contingent on multiple mutations that diminish the affinity of its topoiso- merase II and IV targets in varying ways reduce per- meability, and up regulate efflux 3 .	cache/bjms-12604.pdf	txt/bjms-12604.txt
