id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-10066	Rasul, Azhar; Parveen, Saima; Ma, Tonghui	Costunolide: A novel anti-cancer sesquiterpene lactone	2012	9	.pdf	application/pdf	5484	313	55	Further studies demonstrate that costunolide has anti- tumor potential by inhibiting proliferation, inducing apoptosis and reducing invasion and metastasis of a wide variety of tumor cells, including breast cancer cells (Bocca et al., 2004; Choi et al., 2005; Choi et al., 2011), hepatocellular carcinoma cells (Chen et al., 1995; Liu et al., 2011a; Sun et al., 2003), prostate cancer cells (Hsu et al., 2011), leukemia cells (Choi et al., 2002a; Choi and Lee, 2009; Choi et al., 2002b; Hibasami et al., 2003; Kanno et al., 2008; Kim et al., 2008; Kim et al., 2002; Kim et al., 2011b; Komiya et al., 2004; Lee et al., 2001; Song et al., 2001; Srivastava et al., 2006), gastric cancer cells (Ko et al., 2005; Rasul et al., 2011), colon cancer cells (Kawamori et al., 1995; Mori et al., 1994), melanoma cells (Chen et al., 2007; Park et al., 2001b), cervical cancer cells (Sun et al., 2003), KB and P388 tumor cell (Mondranondra et al., 1990), and platinum-resistant human ovarian cancer cells (Yang et al., 2011). Accumulated data indicate that Costunolide was isola- ted from many plant species such as Saussurea lappa (Lee et al., 2001; Li et al., 2006; Zhang et al., 2011), Aucklandia lappa Decne (Li et al., 2005; Rasul et al., 2011), Michelia floribunda (Mondranondra et al., 1990), Magnolia grandiflora (el-Feraly and Chan, 1978; Wu et al., 2001), Podachaenium eminens (Castro et al., 2000), Magnolia sieboldii (Park et al., 2001a; Park et al., 2001b), Tsoongiodendron odorum Chun (Song et al., 2001), Cosmos pringlei (Mata et al., 2002), Laurus nobilis (De Marino et al., 2005; Matsuda et al., 2002), Laurus novocanariensis (Ferrari et al., 2005), Magnolia kobus (Park et al., 2010), Eupatorium lindleyanum (Yang et al., 2010), and Magnolia ovata (Kassuya et al., 2009).	cache/bjp-10066.pdf	txt/bjp-10066.txt