id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-18965	Sivakumar, Dakshinamurthy; Hari, Natarajan; Sivaraman, Thirunavukkarasu	Computational analyses on delineating specificity of 2-hydroxy-3,5-dinitrobenzamide, a BH3-mimetic, towards anti-apoptotic proteins	2014	6	.pdf	application/pdf	3451	153	51	Bangladesh Journal of Pharmacology Research Article Computational analyses on delineat- ing specificity of 2-hydroxy-3,5- dinitrobenzamide, a BH3-mimetic, towards anti-apoptotic proteins BJP Introduction Apoptosis is tightly regulated by intrinsic pathway activated by Bcl-2 family proteins present in the mitochondrial membrane and anti-apoptotic proteins of the Bcl-2 family are important cancer biomarkers as they are over expressed in all types of cancers (Kelly and Strasser, 2011). Therefore, administration of anti-cancer drugs interacting with anti-apoptotic proteins exhibiting no over expression may presumably cause some adverse effect (such as lymphopenia, thrombocytopaenia and anemia) to cancer patients.	cache/bjp-18965.pdf	txt/bjp-18965.txt