id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-20825	Saleem, Mohammad; Irshad, Iram; Baig, Muhammad Kashif; Naseer, Faiza	Evaluation of hepatoprotective effect of chloroform and methanol extracts of Opuntia monacantha in paracetamol-induced hepatotoxicity in rabbits	2015	6	.pdf	application/pdf	3275	162	55	Then filtration was done with Whatman filter paper No. 1 and the filtrates were concentrated in a rotary evaporator at 61ºC for chloroform extract and at 65ºC for methanol extract. Distill water 0.7 ± 0.0 68.2 ± 4.7 66.8 ± 8.4 117.3 ± 5.3 Distill water + Paracetamol (2,000 mg/kg) 3.3 ± 0.2 165.3 ± 22.4 115.6 ± 12.2 223.3 ± 7.7 Silymarin (100 mg) + Paracetamol (2,000 mg/kg) 0.5 ± 0.0 68.8 ± 7.7 75.5 ± 8.4 133.5 ± 9.9 Chloroform extract (200 mg) + Paracetamol (2,000 mg/kg) 1.8 ± 0.3 98.3 ± 6.6 86.3 ± 4.5 145.6 ± 7.7 Chloroform extract (400 mg) + Paracetamol (2,000 mg/kg) 1.3 ± 0.2 95.3 ± 16.0 82.5 ± 11.9 141.5 ± 9.5 Chloroform extract (600 mg) + Paracetamol (2000 mg/kg) 1.0 ± 0.1 93.6 ± 6.6 80.8 ± 6.4 138.5 ± 6.2 Methanol extract (200 mg) + Paracetamol (2000 mg/kg) 1.6 ± 0.2 99.0 ± 5.9 98.2 ± 6.7 145.0 ± 2.1 Methanol extract (400 mg) + Paracetamol (2,000 mg/kg) 1.2 ± 0.3 80.1 ± 8.0 90.0 ± 5.8 141.7 ± 17.6 Methanol extract (600 mg) + Paracetamol (2,000 mg/kg) 1.1 ± 0.1 76.1 ± 4.7 78.2 ± 7.2 139.5 ± 11.8 Table II Phytochemical analysis of Opuntia monacantha Compounds Chloroform extract Methanol extract Alkaloids + + Polysaccharides + + Tannins + + Saponins + + Flavonoids + + Steroids - - Anthraquinones - - Discussion Paracetamol-induced liver toxicity and cell death are due to generation of toxic metabolites after its meta- bolism through CYP-450 (Ibrahim et al., 2011).	cache/bjp-20825.pdf	txt/bjp-20825.txt