id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-22424	Fan, Mao-Chuan; Han, Guang-Ye; Zhang, Xin-Jun; Xi, Hui-Fang	Studies of in vitro anti-prostate cancer potential of newer 1,2,4-triazolo-1,3,4-thiadiazines with different heteroaromatics	2015	9	.pdf	application/pdf	5038	195	59	3-(3-((1H-benzo[d]imidazol-1-yl)methyl)-7H-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazin-6-yl)-2H-chromen-2- one (1) Yield 71%, m.p. 256-258°C, IR (KBr, cm–1): 3049 (Ar-H), 2988, 2919, 2845 (C-H), 1729 (lactone C=O), 1640 (C=N), 1389 (N=C-S), 1327 (C-N), 1317 (N-N=C), 679 (C-S-C bend-ing); 1H NMR (400 MHz, DMSO–d6): δ 8.49 (s, 1H, –N=CH, benzimidazole), 8.21 (s, 1H, H–4, coumarin), 7.83-7.67 (m, 2H, Ar-H), 7.35-7.43 (m, 2H, coumarin), 7.32-7.17 (m, 2H, Ar-H), 7.05-7.12 (m, 2H, coumarin), 4.21 (s, 2H, S-CH2, thiadiazine), 3.71 (s, 2H, –N–CH2); 13C NMR (100 MHz, DMSO–d6): δ 168.1 (1C, C=O, coumarin), 165.2, 162.6 and 160.1 (3C, C-3, C-6 and C-9, triazolothiadiazine), 153.2 (1C, C-9, coumarin), 152.7 (1C, C–2, benzimidazole), 145.2-116.8 (13C, Ar-C), 43.8 (1C, N–CH2), 41.2 (1C, C-7, CH2, triazolothiadiazine). Found: C, 60.71; H, 3.58; N, 20.16. 3,3'-(7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine-3,6- diyl)bis(2H-chromen-2-one) (2) Yield 68%, m.p. 245-257°C, IR (KBr, cm–1): 3058 (Ar-H), 2988, 2937, 2840 (C-H), 1734 (lactone C=O), 1633 (C=N), 1380 (N=C-S), 1331 (C-N), 1324 (N-N=C), 681 (C-S-C bending); 1H NMR (400 MHz, DMSO–d6): δ 8.34 (s, 1H, H–4, coumarin), 8.37 (s, 1H, H–4, coumarin), 7.29-7.46 (m, 4H, coumarin), 7.04-7.15 (m, 4H, coumarin), 4.27 (s, 2H, S-CH2, thiadiazine); 13C NMR (100 MHz, DMSO– d6): δ 169.1 (1C, C=O, coumarin), 167.8 (1C, C=O, coumarin), 166.1, 163.3 and 159.8 (3C, C-3, C-6 and C-9, triazolothiadiazine), 153.4 (1C, C-9, coumarin), 152.8 (1C, C-9, coumarin), 145.2-125.6 (14C, Ar-C), 41.9 (1C, C -7, CH2, triazolothiadia-zine).	cache/bjp-22424.pdf	txt/bjp-22424.txt