id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-27606	Shou, Di-Wen; Zheng, Yue-Lin	Antitumor activity, cell cycle arrest and apoptosis induction in human colon cancer cell line by Primula macrophylla extracts	2017	8	.pdf	application/pdf	3595	162	51	Treatment of Colo-205 cells with different concentration of extract (0-80 μg/mL) significantly increased the side-scattering (SSC) pro- file due to increased cellular granularity because of chromatin fragmentation and significant decrease in forward-scattering (FSC) profile due to shrinkage of cells 250 200 150 100 50 0 S S C - A 0 µg/mL 250 200 150 100 50 0 S S C - A 10 µg/mL 250 200 150 100 50 0 S S C - A 20 µg/mL 250 200 150 100 50 0 S S C - A 40 µg/mL 101 102 103 104 105 250 200 150 100 50 0 S S C - A FSC-A 80 µg/mL Bangladesh J Pharmacol 2017; 12: 101-106 103 Figure 2: Methanol extract of P. macrophylla induced cell cycle arrest in COLO-205 cells at G0/G1 phase of cell cycle. Effect on dot-blot light scattering One of the important characteristics of any anti-cancer drug is the inhibition of cell growth proliferation and apoptosis induction in cancer cells (Lowe and Lin, 2000).	cache/bjp-27606.pdf	txt/bjp-27606.txt