id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-31428	Arif, Mubeen; Jabeen, Furukh; Saeed, Aamer; Qureshi, Irfan Zia; Mushtaq, Nadia	A new class of potential antidiabetic acetohydrazides: Synthesis, in vivo antidiabetic activity and molecular docking studies	2017	15	.pdf	application/pdf	10847	364	62	N΄-(3-flourobenzylidene)-2-(5-(pyridin-3-yl)-2H- tetrazol-2-yl)acetohydrazide (9l) Yield: 82%; off white solid; m.p.: 263°C (decomp.); Rf: 0.42 (ethyl acetate : n-hexane 2:1); FTIR (ATR, υ/cm-1): 3376 (N-H), 3116 (Ar C-H), 1685 (C=N), 1665 (amide C=O), 1571 (Ar C=C), 1271 (N=N-N); 1H NMR (300 MHz, DMSO-d6): δ 12.08 (br, 1H, NH), 9.21 (d, J = 1.5 Hz, 1H, Ar-H), 8.74 (dd, J = 1.5, 4.8 Hz, 1H, Ar-H), 8.60- 8.51 (m, 1H, Ar-H), 8.21 (s, 1H, CH=N), 7.81-7.62 (m, 4H, Ar-H), 7.54-7.47 (m, 1H, Ar-H), 6.15 (s, 2H, CH2); 13C NMR: (75 MHz, DMSO-d6): 166.9 (C=O) , 163.0 322 Bangladesh J Pharmacol 2017; 12: 319-332 (C=N, tetrazole), 162.8, 159.9, 152.1, 147.1, 138.2, 135.7, 134.1, 132.8, 129.7, 126.0, 121.4, 119.6, 54.23; LC-MS (m/ z): (M)+, 326; Elemental analysis calculation for C15H12FN7O (%): C, 55.38; H, 3.72; N, 30.14; Found: C, 55.27; H, 3.81; N, 30.16. N΄-(2-flourobenzylidene)-2-(5-(pyridin-3-yl)-2H- tetrazol-2-yl)acetohydrazide (9m) Yield: 80%; off white solid; m.p.: 252°C (decomp.); Rf: 0.42 (ethyl acetate : n-hexane 2:1); FTIR (ATR, υ/cm-1): 3387 (N-H), 3117 (Ar C-H), 1687 (C=N), 1662 (amide C=O), 1588 (Ar C=C), 1277 (N=N-N); 1H NMR (300 MHz, DMSO-d6): δ 12.10 (br, 1H, NH), 9.25 (s, 1H, Ar- H), 8.82-8.74 (m, 1H, Ar-H), 8.50-8.42 (m, 1H, Ar-H), 8.28 (s, 1H, CH=N), 8.05-7.88 (m, 1H, Ar-H), 7.62 (dd, J = 8.1, 4.8 Hz, 1H, Ar-H), 7.54-7.46 (m, 1H, Ar-H), 7.33- 7.29 (m, 2H, Ar-H), 6.20 (s, 2H, CH2); 13C NMR: (75 MHz, DMSO-d6): 166.7 (C=O), 162.8 (C=N, tetrazole), 162.6, 159.5, 151.9, 147.6, 138.3, 138.2, 134.4, 132.7, 127.1, 125.3, 124.8, 123.4; LC-MS (m/z): (M)+, 326; Elemental analysis calculation for C15H12FN7O (%): C, 55.38; H, 3.72; N, 30.14; Found: C, 55.27; H, 3.81; N, 30.16.	cache/bjp-31428.pdf	txt/bjp-31428.txt