id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-4693	Devnath, Hari Pado; Islam, Md. Rabiul	Synthesis of some pyrazolone derivatives from ciprofloxacin and study of their cytotoxicity	2010	4	.pdf	application/pdf	2101	87	59	Rf values (CHCHMeOH =9:1) Color of compounds 1a 88 215 0.74 White 1b 82 203 0.73 Yellow 1c 88 220 0.69 White brown Table II Cytotoxicity activity (IC50, after 4 hours) of synthesized compounds against brine shrimps Tested compounds Concentration of sample (µg/mL) % of mortality IC50 (in gg/mL) Remarks 1 0.1 63.6 0.04 Moderately active 0.1 81.8 0.2 80.0 1.0 80.0 1a 0.1 71.4 0.02 Highly active 0.1 76.7 0.2 78.9 1.0 80.0 1b 0.1 81.8 0.02 Very highly active 0.1 81.8 0.2 90.0 1.0 100.0 1c 0.1 80.0 0.02 Highly active 0.1 88.9 0.2 88.9 1.0 100.0 IC50: 0.01-0.02, very highly active; IC50: 0.02-0.03, highly active; IC50: 0.03-0.04 moderately active; IC50: 0.04-0.05, Active; IC50: >45, weakly active Author Info Md. The resulting spectral data analyses of synthesized compounds: Compound 1a: IR (vmax, KBr, cm-1): 3200.6 cm-1(s, sh, VN- H); 3070 cm-1((s, sh, VC-H, aromatic); 920 cm-1(s, sh, VC-H, aromatic, out of plane); 2961 cm-1(w, sh, VC-H CH2); 1447.5 and 1378 cm-1(s, sh, vC-H bending, CH2); 1612 and 1490 cm-1(s, sh, vc-c, aromatic); 1604 cm-1(s, sh, VC-N); 1700 cm-1(s, sh, VC=O, lactam), 1576 cm-1(s, sh, VN -H, bending); 1652 cm-1(m, VC=C, alkene); 1028 cm-1(s, sh, vc- N amine); 858 cm-1(s, br., VN-H, wagging); 752 cm -1(s, sh, VC-F ).	cache/bjp-4693.pdf	txt/bjp-4693.txt