id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bjp-79655	Yin, Hao; Xue, Yi; Wang, Xin	1α,25-Dihydroxyvitamin D3 reduces uropathogenic E. coli persistence in bladder epithelial cells by restoring lysosome acidification	2025	9	.pdf	application/pdf	4940	225	54	1,25(OH)2D3 enhances lysosomal acidification in E. coli -infected HTB-9 cells Western blot analysis showed no significant difference in the expression level of lysosome-associated mem- 6000 4000 2000 0 C F U i n H T B -9 c e ll E. coli - + + - + + - + + 1,25-VD3 - - + - - + - - + 2500 2000 1500 1000 500 0 2000 1500 1000 500 0 ns a a A B C Figure 1: Effect of 1,25(OH)2D3 (1,25-VD3, 10 nM) on the intracellular persistent bacterial count of HTB-9 cells infected with E. coli. However, different from the other studies, this study focuses on the role of 1,25(OH)2D3 in enhan- cing the lysosomal acidification of HTB-9 cells and inhibiting the persistence of E. coli.	cache/bjp-79655.pdf	txt/bjp-79655.txt