id	sid	tid	token	lemma	pos
bjp-19567	1	1	bangladesh	bangladesh	PROPN
bjp-19567	1	2	journal	journal	PROPN
bjp-19567	1	3	of	of	ADP
bjp-19567	1	4	pharmacology	pharmacology	NOUN
bjp-19567	1	5	research	research	NOUN
bjp-19567	1	6	article	article	NOUN
bjp-19567	1	7	nobiletin	nobiletin	NOUN
bjp-19567	1	8	acts	act	NOUN
bjp-19567	1	9	as	as	ADP
bjp-19567	1	10	a	a	DET
bjp-19567	1	11	potential	potential	ADJ
bjp-19567	1	12	anticancer	anticancer	NOUN
bjp-19567	1	13	agent	agent	NOUN
bjp-19567	1	14	against	against	ADP
bjp-19567	1	15	osteosarcoma	osteosarcoma	NOUN
bjp-19567	1	16	by	by	ADP
bjp-19567	1	17	regulating	regulate	VERB
bjp-19567	1	18	erk	erk	PROPN
bjp-19567	1	19	and	and	CCONJ
bjp-19567	1	20	akt	akt	PROPN
bjp-19567	1	21	signaling	signal	VERB
bjp-19567	1	22	pathways	pathway	NOUN
bjp-19567	1	23	bjp	bjp	NOUN
bjp-19567	1	24	introduction	introduction	NOUN
bjp-19567	1	25	skeletal	skeletal	ADJ
bjp-19567	1	26	integrity	integrity	NOUN
bjp-19567	1	27	is	be	AUX
bjp-19567	1	28	maintained	maintain	VERB
bjp-19567	1	29	by	by	ADP
bjp-19567	1	30	equilibrium	equilibrium	NOUN
bjp-19567	1	31	between	between	ADP
bjp-19567	1	32	osteoblasts	osteoblast	NOUN
bjp-19567	1	33	mediated	mediate	VERB
bjp-19567	1	34	bone	bone	NOUN
bjp-19567	1	35	formation	formation	NOUN
bjp-19567	1	36	and	and	CCONJ
bjp-19567	1	37	osteoclasts	osteoclast	NOUN
bjp-19567	1	38	mediated	mediate	VERB
bjp-19567	1	39	bone	bone	NOUN
bjp-19567	1	40	resorption	resorption	NOUN
bjp-19567	1	41	.	.	PUNCT
bjp-19567	2	1	any	any	DET
bjp-19567	2	2	imbalance	imbalance	NOUN
bjp-19567	2	3	in	in	ADP
bjp-19567	2	4	this	this	DET
bjp-19567	2	5	equilibrium	equilibrium	NOUN
bjp-19567	2	6	leads	lead	VERB
bjp-19567	2	7	to	to	ADP
bjp-19567	2	8	osteoblastic	osteoblastic	ADJ
bjp-19567	2	9	lesions	lesion	NOUN
bjp-19567	2	10	and	and	CCONJ
bjp-19567	2	11	other	other	ADJ
bjp-19567	2	12	severe	severe	ADJ
bjp-19567	2	13	clinical	clinical	ADJ
bjp-19567	2	14	consequences	consequence	NOUN
bjp-19567	2	15	often	often	ADV
bjp-19567	2	16	termed	term	VERB
bjp-19567	2	17	as	as	ADP
bjp-19567	2	18	bone	bone	NOUN
bjp-19567	2	19	cancer	cancer	NOUN
bjp-19567	2	20	or	or	CCONJ
bjp-19567	2	21	osteosarcoma	osteosarcoma	ADJ
bjp-19567	2	22	.	.	PUNCT
bjp-19567	3	1	commonly	commonly	ADV
bjp-19567	3	2	,	,	PUNCT
bjp-19567	3	3	bone	bone	NOUN
bjp-19567	3	4	cancer	cancer	NOUN
bjp-19567	3	5	is	be	AUX
bjp-19567	3	6	resulted	result	VERB
bjp-19567	3	7	by	by	ADP
bjp-19567	3	8	invasion	invasion	NOUN
bjp-19567	3	9	of	of	ADP
bjp-19567	3	10	different	different	ADJ
bjp-19567	3	11	cancers	cancer	NOUN
bjp-19567	3	12	to	to	ADP
bjp-19567	3	13	bone	bone	NOUN
bjp-19567	3	14	tissue	tissue	NOUN
bjp-19567	3	15	,	,	PUNCT
bjp-19567	3	16	phenomenon	phenomenon	NOUN
bjp-19567	3	17	known	know	VERB
bjp-19567	3	18	as	as	ADP
bjp-19567	3	19	bone	bone	NOUN
bjp-19567	3	20	metastases	metastasis	NOUN
bjp-19567	3	21	.	.	PUNCT
bjp-19567	4	1	american	american	ADJ
bjp-19567	4	2	cancer	cancer	PROPN
bjp-19567	4	3	society	society	PROPN
bjp-19567	4	4	estimates	estimate	VERB
bjp-19567	4	5	nearly	nearly	ADV
bjp-19567	4	6	3,020	3,020	NUM
bjp-19567	4	7	new	new	ADJ
bjp-19567	4	8	cases	case	NOUN
bjp-19567	4	9	of	of	ADP
bjp-19567	4	10	bone	bone	NOUN
bjp-19567	4	11	cancer	cancer	NOUN
bjp-19567	4	12	and	and	CCONJ
bjp-19567	4	13	1,460	1,460	NUM
bjp-19567	4	14	deaths	death	NOUN
bjp-19567	4	15	due	due	ADP
bjp-19567	4	16	to	to	ADP
bjp-19567	4	17	bone	bone	NOUN
bjp-19567	4	18	cancer	cancer	NOUN
bjp-19567	4	19	in	in	ADP
bjp-19567	4	20	2014	2014	NUM
bjp-19567	4	21	(	(	PUNCT
bjp-19567	4	22	american	american	ADJ
bjp-19567	4	23	cancer	cancer	NOUN
bjp-19567	4	24	society	society	NOUN
bjp-19567	4	25	,	,	PUNCT
bjp-19567	4	26	2014	2014	NUM
bjp-19567	4	27	)	)	PUNCT
bjp-19567	4	28	.	.	PUNCT
bjp-19567	5	1	although	although	SCONJ
bjp-19567	5	2	,	,	PUNCT
bjp-19567	5	3	many	many	ADJ
bjp-19567	5	4	chemotherapeutic	chemotherapeutic	ADJ
bjp-19567	5	5	drugs	drug	NOUN
bjp-19567	5	6	are	be	AUX
bjp-19567	5	7	currently	currently	ADV
bjp-19567	5	8	employed	employ	VERB
bjp-19567	5	9	for	for	ADP
bjp-19567	5	10	the	the	DET
bjp-19567	5	11	treatment	treatment	NOUN
bjp-19567	5	12	of	of	ADP
bjp-19567	5	13	bone	bone	NOUN
bjp-19567	5	14	cancer	cancer	NOUN
bjp-19567	5	15	,	,	PUNCT
bjp-19567	5	16	yet	yet	CCONJ
bjp-19567	5	17	there	there	PRON
bjp-19567	5	18	is	be	VERB
bjp-19567	5	19	demand	demand	NOUN
bjp-19567	5	20	for	for	ADP
bjp-19567	5	21	safe	safe	ADJ
bjp-19567	5	22	and	and	CCONJ
bjp-19567	5	23	novel	novel	ADJ
bjp-19567	5	24	drugs	drug	NOUN
bjp-19567	5	25	having	have	VERB
bjp-19567	5	26	minimum	minimum	ADJ
bjp-19567	5	27	side	side	NOUN
bjp-19567	5	28	effects	effect	NOUN
bjp-19567	5	29	.	.	PUNCT
bjp-19567	6	1	over	over	ADP
bjp-19567	6	2	the	the	DET
bjp-19567	6	3	past	past	ADJ
bjp-19567	6	4	few	few	ADJ
bjp-19567	6	5	years	year	NOUN
bjp-19567	6	6	,	,	PUNCT
bjp-19567	6	7	the	the	DET
bjp-19567	6	8	development	development	NOUN
bjp-19567	6	9	of	of	ADP
bjp-19567	6	10	natural	natural	ADJ
bjp-19567	6	11	compounds	compound	NOUN
bjp-19567	6	12	as	as	SCONJ
bjp-19567	6	13	anticancer	anticancer	NOUN
bjp-19567	6	14	agents	agent	NOUN
bjp-19567	6	15	has	have	AUX
bjp-19567	6	16	been	be	AUX
bjp-19567	6	17	revealed	reveal	VERB
bjp-19567	6	18	(	(	PUNCT
bjp-19567	6	19	newman	newman	PROPN
bjp-19567	6	20	and	and	CCONJ
bjp-19567	6	21	cragg	cragg	PROPN
bjp-19567	6	22	,	,	PUNCT
bjp-19567	6	23	2007	2007	NUM
bjp-19567	6	24	)	)	PUNCT
bjp-19567	6	25	.	.	PUNCT
bjp-19567	7	1	intensive	intensive	ADJ
bjp-19567	7	2	efforts	effort	NOUN
bjp-19567	7	3	for	for	ADP
bjp-19567	7	4	discovering	discover	VERB
bjp-19567	7	5	new	new	ADJ
bjp-19567	7	6	drugs	drug	NOUN
bjp-19567	7	7	based	base	VERB
bjp-19567	7	8	on	on	ADP
bjp-19567	7	9	natural	natural	ADJ
bjp-19567	7	10	products	product	NOUN
bjp-19567	7	11	has	have	AUX
bjp-19567	7	12	proven	prove	VERB
bjp-19567	7	13	beneficial	beneficial	ADJ
bjp-19567	7	14	,	,	PUNCT
bjp-19567	7	15	with	with	ADP
bjp-19567	7	16	nearly	nearly	ADV
bjp-19567	7	17	47	47	NUM
bjp-19567	7	18	%	%	NOUN
bjp-19567	7	19	drugs	drug	NOUN
bjp-19567	7	20	of	of	ADP
bjp-19567	7	21	natural	natural	ADJ
bjp-19567	7	22	origin	origin	NOUN
bjp-19567	7	23	been	be	AUX
bjp-19567	7	24	approved	approve	VERB
bjp-19567	7	25	as	as	ADP
bjp-19567	7	26	anticancer	anticancer	NOUN
bjp-19567	7	27	agents	agent	NOUN
bjp-19567	7	28	.	.	PUNCT
bjp-19567	8	1	flavonoids	flavonoid	NOUN
bjp-19567	8	2	are	be	AUX
bjp-19567	8	3	a	a	DET
bjp-19567	8	4	group	group	NOUN
bjp-19567	8	5	of	of	ADP
bjp-19567	8	6	natural	natural	ADJ
bjp-19567	8	7	polyphenols	polyphenol	NOUN
bjp-19567	8	8	widely	widely	ADV
bjp-19567	8	9	present	present	ADJ
bjp-19567	8	10	in	in	ADP
bjp-19567	8	11	plants	plant	NOUN
bjp-19567	8	12	and	and	CCONJ
bjp-19567	8	13	well	well	ADV
bjp-19567	8	14	known	know	VERB
bjp-19567	8	15	to	to	PART
bjp-19567	8	16	play	play	VERB
bjp-19567	8	17	significant	significant	ADJ
bjp-19567	8	18	role	role	NOUN
bjp-19567	8	19	in	in	ADP
bjp-19567	8	20	various	various	ADJ
bjp-19567	8	21	pharmacological	pharmacological	ADJ
bjp-19567	8	22	activities	activity	NOUN
bjp-19567	8	23	(	(	PUNCT
bjp-19567	8	24	harborne	harborne	NOUN
bjp-19567	8	25	and	and	CCONJ
bjp-19567	8	26	williams	williams	PROPN
bjp-19567	8	27	,	,	PUNCT
bjp-19567	8	28	2000	2000	NUM
bjp-19567	8	29	;	;	PUNCT
bjp-19567	8	30	kim	kim	PROPN
bjp-19567	8	31	et	et	PROPN
bjp-19567	8	32	al	al	PROPN
bjp-19567	8	33	.	.	PROPN
bjp-19567	8	34	,	,	PUNCT
bjp-19567	8	35	2013	2013	NUM
bjp-19567	8	36	)	)	PUNCT
bjp-19567	8	37	.	.	PUNCT
bjp-19567	9	1	recent	recent	ADJ
bjp-19567	9	2	studies	study	NOUN
bjp-19567	9	3	highlighted	highlight	VERB
bjp-19567	9	4	the	the	DET
bjp-19567	9	5	anti	anti	ADJ
bjp-19567	9	6	-	-	ADJ
bjp-19567	9	7	cancer	cancer	ADJ
bjp-19567	9	8	potential	potential	NOUN
bjp-19567	9	9	of	of	ADP
bjp-19567	9	10	these	these	DET
bjp-19567	9	11	flavonoids	flavonoid	NOUN
bjp-19567	9	12	and	and	CCONJ
bjp-19567	9	13	explored	explore	VERB
bjp-19567	9	14	as	as	ADP
bjp-19567	9	15	therapeutic	therapeutic	ADJ
bjp-19567	9	16	drugs	drug	NOUN
bjp-19567	9	17	in	in	ADP
bjp-19567	9	18	clinics	clinic	NOUN
bjp-19567	9	19	(	(	PUNCT
bjp-19567	9	20	neuhauser	neuhauser	NOUN
bjp-19567	9	21	,	,	PUNCT
bjp-19567	9	22	2004	2004	NUM
bjp-19567	9	23	)	)	PUNCT
bjp-19567	9	24	.	.	PUNCT
bjp-19567	10	1	nobiletin	nobiletin	NOUN
bjp-19567	10	2	(	(	PUNCT
bjp-19567	10	3	5,6,7,8,3',4'-hexamethoxy	5,6,7,8,3',4'-hexamethoxy	NUM
bjp-19567	10	4	flavone	flavone	NOUN
bjp-19567	10	5	)	)	PUNCT
bjp-19567	10	6	,	,	PUNCT
bjp-19567	10	7	a	a	DET
bjp-19567	10	8	flavonoid	flavonoid	NOUN
bjp-19567	10	9	,	,	PUNCT
bjp-19567	10	10	is	be	AUX
bjp-19567	10	11	present	present	ADJ
bjp-19567	10	12	in	in	ADP
bjp-19567	10	13	citrus	citrus	NOUN
bjp-19567	10	14	fruits	fruit	NOUN
bjp-19567	10	15	and	and	CCONJ
bjp-19567	10	16	found	find	VERB
bjp-19567	10	17	to	to	PART
bjp-19567	10	18	possess	possess	VERB
bjp-19567	10	19	anti	anti	ADJ
bjp-19567	10	20	-inflammatory	-inflammatory	NOUN
bjp-19567	10	21	(	(	PUNCT
bjp-19567	10	22	murakami	murakami	NOUN
bjp-19567	10	23	et	et	PROPN
bjp-19567	10	24	al	al	PROPN
bjp-19567	10	25	.	.	PROPN
bjp-19567	10	26	,	,	PUNCT
bjp-19567	10	27	2005	2005	NUM
bjp-19567	10	28	)	)	PUNCT
bjp-19567	10	29	and	and	CCONJ
bjp-19567	10	30	antitumor	antitumor	PROPN
bjp-19567	10	31	potential	potential	NOUN
bjp-19567	10	32	(	(	PUNCT
bjp-19567	10	33	tang	tang	X
bjp-19567	10	34	et	et	PROPN
bjp-19567	10	35	al	al	PROPN
bjp-19567	10	36	.	.	PROPN
bjp-19567	10	37	,	,	PUNCT
bjp-19567	10	38	2007	2007	NUM
bjp-19567	10	39	;	;	PUNCT
bjp-19567	10	40	sato	sato	PROPN
bjp-19567	10	41	et	et	PROPN
bjp-19567	10	42	al	al	PROPN
bjp-19567	10	43	.	.	PROPN
bjp-19567	10	44	,	,	PUNCT
bjp-19567	10	45	2002	2002	NUM
bjp-19567	10	46	)	)	PUNCT
bjp-19567	10	47	.	.	PUNCT
bjp-19567	11	1	previous	previous	ADJ
bjp-19567	11	2	studies	study	NOUN
bjp-19567	11	3	showed	show	VERB
bjp-19567	11	4	the	the	DET
bjp-19567	11	5	anti	anti	ADJ
bjp-19567	11	6	-	-	ADJ
bjp-19567	11	7	proliferative	proliferative	ADJ
bjp-19567	11	8	effect	effect	NOUN
bjp-19567	11	9	of	of	ADP
bjp-19567	11	10	nobiletin	nobiletin	NOUN
bjp-19567	11	11	on	on	ADP
bjp-19567	11	12	various	various	ADJ
bjp-19567	11	13	cell	cell	NOUN
bjp-19567	11	14	lines	line	NOUN
bjp-19567	11	15	including	include	VERB
bjp-19567	11	16	lung	lung	NOUN
bjp-19567	11	17	adenocarcinoma	adenocarcinoma	NOUN
bjp-19567	11	18	cell	cell	NOUN
bjp-19567	11	19	line	line	NOUN
bjp-19567	11	20	a549	a549	PROPN
bjp-19567	11	21	cells	cell	NOUN
bjp-19567	11	22	(	(	PUNCT
bjp-19567	11	23	luo	luo	PROPN
bjp-19567	11	24	et	et	PROPN
bjp-19567	11	25	al	al	PROPN
bjp-19567	11	26	.	.	PROPN
bjp-19567	11	27	,	,	PUNCT
bjp-19567	11	28	2008	2008	NUM
bjp-19567	11	29	)	)	PUNCT
bjp-19567	11	30	and	and	CCONJ
bjp-19567	11	31	hepatic	hepatic	ADJ
bjp-19567	11	32	cancer	cancer	NOUN
bjp-19567	11	33	cell	cell	NOUN
bjp-19567	11	34	line	line	NOUN
bjp-19567	11	35	,	,	PUNCT
bjp-19567	11	36	smmc-7721	smmc-7721	PROPN
bjp-19567	11	37	(	(	PUNCT
bjp-19567	11	38	ma	ma	PROPN
bjp-19567	11	39	et	et	PROPN
bjp-19567	11	40	al	al	PROPN
bjp-19567	11	41	.	.	PROPN
bjp-19567	11	42	,	,	PUNCT
bjp-19567	11	43	2014	2014	NUM
bjp-19567	11	44	)	)	PUNCT
bjp-19567	11	45	.	.	PUNCT
bjp-19567	12	1	however	however	ADV
bjp-19567	12	2	,	,	PUNCT
bjp-19567	12	3	the	the	DET
bjp-19567	12	4	anti	anti	ADJ
bjp-19567	12	5	-	-	ADJ
bjp-19567	12	6	proliferative	proliferative	ADJ
bjp-19567	12	7	effect	effect	NOUN
bjp-19567	12	8	of	of	ADP
bjp-19567	12	9	nobiletin	nobiletin	NOUN
bjp-19567	12	10	on	on	ADP
bjp-19567	12	11	osteosarcoma	osteosarcoma	ADJ
bjp-19567	12	12	cells	cell	NOUN
bjp-19567	12	13	has	have	AUX
bjp-19567	12	14	not	not	PART
bjp-19567	12	15	been	be	AUX
bjp-19567	12	16	studied	study	VERB
bjp-19567	12	17	till	till	SCONJ
bjp-19567	12	18	date	date	NOUN
bjp-19567	12	19	.	.	PUNCT
bjp-19567	13	1	furthermore	furthermore	ADV
bjp-19567	13	2	,	,	PUNCT
bjp-19567	13	3	the	the	DET
bjp-19567	13	4	mechanism	mechanism	NOUN
bjp-19567	13	5	of	of	ADP
bjp-19567	13	6	anti	anti	ADJ
bjp-19567	13	7	-	-	ADJ
bjp-19567	13	8	cancer	cancer	ADJ
bjp-19567	13	9	action	action	NOUN
bjp-19567	13	10	exerted	exert	VERB
bjp-19567	13	11	by	by	ADP
bjp-19567	13	12	nobiletin	nobiletin	NOUN
bjp-19567	13	13	is	be	AUX
bjp-19567	13	14	a	a	DET
bjp-19567	13	15	journal	journal	NOUN
bjp-19567	13	16	of	of	ADP
bjp-19567	13	17	the	the	DET
bjp-19567	13	18	bangladesh	bangladesh	NOUN
bjp-19567	13	19	pharmacological	pharmacological	ADJ
bjp-19567	13	20	society	society	NOUN
bjp-19567	13	21	(	(	PUNCT
bjp-19567	13	22	bdps	bdps	NOUN
bjp-19567	13	23	)	)	PUNCT
bjp-19567	13	24	bangladesh	bangladesh	PROPN
bjp-19567	13	25	j	j	PROPN
bjp-19567	13	26	pharmacol	pharmacol	PROPN
bjp-19567	13	27	2014	2014	NUM
bjp-19567	13	28	;	;	PUNCT
bjp-19567	13	29	9	9	NUM
bjp-19567	13	30	:	:	SYM
bjp-19567	13	31	406	406	NUM
bjp-19567	13	32	-	-	SYM
bjp-19567	13	33	412	412	NUM
bjp-19567	13	34	journal	journal	NOUN
bjp-19567	13	35	homepage	homepage	NOUN
bjp-19567	13	36	:	:	PUNCT
bjp-19567	13	37	www.banglajol.info	www.banglajol.info	PROPN
bjp-19567	13	38	abstracted	abstract	VERB
bjp-19567	13	39	/	/	SYM
bjp-19567	13	40	indexed	index	VERB
bjp-19567	13	41	in	in	ADP
bjp-19567	13	42	academic	academic	ADJ
bjp-19567	13	43	search	search	NOUN
bjp-19567	13	44	complete	complete	ADJ
bjp-19567	13	45	,	,	PUNCT
bjp-19567	13	46	agroforestry	agroforestry	NOUN
bjp-19567	13	47	abstracts	abstract	NOUN
bjp-19567	13	48	,	,	PUNCT
bjp-19567	13	49	asia	asia	PROPN
bjp-19567	13	50	journals	journal	NOUN
bjp-19567	13	51	online	online	ADV
bjp-19567	13	52	,	,	PUNCT
bjp-19567	13	53	bangladesh	bangladesh	NOUN
bjp-19567	13	54	journals	journal	NOUN
bjp-19567	13	55	online	online	ADV
bjp-19567	13	56	,	,	PUNCT
bjp-19567	13	57	biological	biological	ADJ
bjp-19567	13	58	abstracts	abstract	NOUN
bjp-19567	13	59	,	,	PUNCT
bjp-19567	13	60	biosis	biosis	NOUN
bjp-19567	13	61	previews	preview	NOUN
bjp-19567	13	62	,	,	PUNCT
bjp-19567	13	63	cab	cab	NOUN
bjp-19567	13	64	abstracts	abstract	NOUN
bjp-19567	13	65	,	,	PUNCT
bjp-19567	13	66	current	current	ADJ
bjp-19567	13	67	abstracts	abstract	NOUN
bjp-19567	13	68	,	,	PUNCT
bjp-19567	13	69	directory	directory	NOUN
bjp-19567	13	70	of	of	ADP
bjp-19567	13	71	open	open	ADJ
bjp-19567	13	72	access	access	NOUN
bjp-19567	13	73	journals	journal	NOUN
bjp-19567	13	74	,	,	PUNCT
bjp-19567	13	75	embase	embase	NOUN
bjp-19567	13	76	/	/	SYM
bjp-19567	13	77	excerpta	excerpta	NOUN
bjp-19567	13	78	medica	medica	NOUN
bjp-19567	13	79	,	,	PUNCT
bjp-19567	13	80	global	global	ADJ
bjp-19567	13	81	health	health	NOUN
bjp-19567	13	82	,	,	PUNCT
bjp-19567	13	83	google	google	PROPN
bjp-19567	13	84	scholar	scholar	NOUN
bjp-19567	13	85	,	,	PUNCT
bjp-19567	13	86	hinari	hinari	X
bjp-19567	13	87	(	(	PUNCT
bjp-19567	13	88	who	who	PRON
bjp-19567	13	89	)	)	PUNCT
bjp-19567	13	90	,	,	PUNCT
bjp-19567	13	91	international	international	ADJ
bjp-19567	13	92	pharmaceutical	pharmaceutical	ADJ
bjp-19567	13	93	abstracts	abstract	NOUN
bjp-19567	13	94	,	,	PUNCT
bjp-19567	13	95	open	open	ADJ
bjp-19567	13	96	j	j	PROPN
bjp-19567	13	97	-	-	PUNCT
bjp-19567	13	98	gate	gate	NOUN
bjp-19567	13	99	,	,	PUNCT
bjp-19567	13	100	science	science	NOUN
bjp-19567	13	101	citation	citation	NOUN
bjp-19567	13	102	index	index	NOUN
bjp-19567	13	103	expanded	expand	VERB
bjp-19567	13	104	,	,	PUNCT
bjp-19567	13	105	scopus	scopus	NOUN
bjp-19567	13	106	and	and	CCONJ
bjp-19567	13	107	social	social	ADJ
bjp-19567	13	108	sciences	sciences	PROPN
bjp-19567	13	109	citation	citation	NOUN
bjp-19567	13	110	index	index	NOUN
bjp-19567	13	111	issn	issn	PROPN
bjp-19567	13	112	:	:	PUNCT
bjp-19567	13	113	1991	1991	NUM
bjp-19567	13	114	-	-	SYM
bjp-19567	13	115	0088	0088	NUM
bjp-19567	13	116	abstract	abstract	NOUN
bjp-19567	13	117	the	the	DET
bjp-19567	13	118	current	current	ADJ
bjp-19567	13	119	study	study	NOUN
bjp-19567	13	120	was	be	AUX
bjp-19567	13	121	aimed	aim	VERB
bjp-19567	13	122	to	to	PART
bjp-19567	13	123	evaluate	evaluate	VERB
bjp-19567	13	124	the	the	DET
bjp-19567	13	125	anti	anti	ADJ
bjp-19567	13	126	-	-	ADJ
bjp-19567	13	127	proliferative	proliferative	ADJ
bjp-19567	13	128	activity	activity	NOUN
bjp-19567	13	129	of	of	ADP
bjp-19567	13	130	nobiletin	nobiletin	NOUN
bjp-19567	13	131	,	,	PUNCT
bjp-19567	13	132	a	a	DET
bjp-19567	13	133	flavonoid	flavonoid	NOUN
bjp-19567	13	134	,	,	PUNCT
bjp-19567	13	135	on	on	ADP
bjp-19567	13	136	osteosarcoma	osteosarcoma	ADJ
bjp-19567	13	137	cell	cell	NOUN
bjp-19567	13	138	line	line	NOUN
bjp-19567	13	139	,	,	PUNCT
bjp-19567	13	140	saos-2	saos-2	NUM
bjp-19567	13	141	.	.	PUNCT
bjp-19567	14	1	furthermore	furthermore	ADV
bjp-19567	14	2	,	,	PUNCT
bjp-19567	14	3	we	we	PRON
bjp-19567	14	4	attempted	attempt	VERB
bjp-19567	14	5	to	to	PART
bjp-19567	14	6	investigate	investigate	VERB
bjp-19567	14	7	the	the	DET
bjp-19567	14	8	signaling	signal	VERB
bjp-19567	14	9	pathways	pathway	NOUN
bjp-19567	14	10	involved	involve	VERB
bjp-19567	14	11	in	in	ADP
bjp-19567	14	12	the	the	DET
bjp-19567	14	13	cell	cell	NOUN
bjp-19567	14	14	growth	growth	NOUN
bjp-19567	14	15	inhibition	inhibition	NOUN
bjp-19567	14	16	mechanism	mechanism	NOUN
bjp-19567	14	17	.	.	PUNCT
bjp-19567	15	1	upon	upon	SCONJ
bjp-19567	15	2	exposure	exposure	NOUN
bjp-19567	15	3	,	,	PUNCT
bjp-19567	15	4	nobiletin	nobiletin	NOUN
bjp-19567	15	5	showed	show	VERB
bjp-19567	15	6	significant	significant	ADJ
bjp-19567	15	7	cell	cell	NOUN
bjp-19567	15	8	inhibitory	inhibitory	ADJ
bjp-19567	15	9	effect	effect	NOUN
bjp-19567	15	10	on	on	ADP
bjp-19567	15	11	saos-2	saos-2	NUM
bjp-19567	15	12	cells	cell	NOUN
bjp-19567	15	13	in	in	ADP
bjp-19567	15	14	a	a	DET
bjp-19567	15	15	dose	dose	NOUN
bjp-19567	15	16	-	-	PUNCT
bjp-19567	15	17	dependent	dependent	ADJ
bjp-19567	15	18	manner	manner	NOUN
bjp-19567	15	19	as	as	SCONJ
bjp-19567	15	20	evidenced	evidence	VERB
bjp-19567	15	21	by	by	ADP
bjp-19567	15	22	mtt	mtt	NOUN
bjp-19567	15	23	assay	assay	NOUN
bjp-19567	15	24	and	and	CCONJ
bjp-19567	15	25	ldh	ldh	PROPN
bjp-19567	15	26	assay	assay	NOUN
bjp-19567	15	27	.	.	PUNCT
bjp-19567	16	1	moreover	moreover	ADV
bjp-19567	16	2	,	,	PUNCT
bjp-19567	16	3	flow	flow	VERB
bjp-19567	16	4	cytometric	cytometric	ADJ
bjp-19567	16	5	analysis	analysis	NOUN
bjp-19567	16	6	demonstrated	demonstrate	VERB
bjp-19567	16	7	that	that	SCONJ
bjp-19567	16	8	upon	upon	SCONJ
bjp-19567	16	9	treatment	treatment	NOUN
bjp-19567	16	10	with	with	ADP
bjp-19567	16	11	nobiletin	nobiletin	NOUN
bjp-19567	16	12	,	,	PUNCT
bjp-19567	16	13	saos-2	saos-2	NUM
bjp-19567	16	14	cells	cell	NOUN
bjp-19567	16	15	underwent	undergo	VERB
bjp-19567	16	16	apoptosis	apoptosis	NOUN
bjp-19567	16	17	and	and	CCONJ
bjp-19567	16	18	showed	show	VERB
bjp-19567	16	19	increased	increase	VERB
bjp-19567	16	20	number	number	NOUN
bjp-19567	16	21	of	of	ADP
bjp-19567	16	22	cells	cell	NOUN
bjp-19567	16	23	arrested	arrest	VERB
bjp-19567	16	24	in	in	ADP
bjp-19567	16	25	g2	g2	PROPN
bjp-19567	16	26	/	/	SYM
bjp-19567	16	27	m	m	PROPN
bjp-19567	16	28	phase	phase	NOUN
bjp-19567	16	29	.	.	PUNCT
bjp-19567	17	1	activation	activation	NOUN
bjp-19567	17	2	of	of	ADP
bjp-19567	17	3	caspase-9	caspase-9	PROPN
bjp-19567	17	4	and	and	CCONJ
bjp-19567	17	5	-3	-3	PUNCT
bjp-19567	17	6	indicate	indicate	VERB
bjp-19567	17	7	the	the	DET
bjp-19567	17	8	activation	activation	NOUN
bjp-19567	17	9	of	of	ADP
bjp-19567	17	10	apoptotic	apoptotic	ADJ
bjp-19567	17	11	signaling	signal	VERB
bjp-19567	17	12	pathway	pathway	NOUN
bjp-19567	17	13	in	in	ADP
bjp-19567	17	14	saos-2	saos-2	NUM
bjp-19567	17	15	cells	cell	NOUN
bjp-19567	17	16	.	.	PUNCT
bjp-19567	18	1	additionally	additionally	ADV
bjp-19567	18	2	,	,	PUNCT
bjp-19567	18	3	it	it	PRON
bjp-19567	18	4	was	be	AUX
bjp-19567	18	5	observed	observe	VERB
bjp-19567	18	6	that	that	SCONJ
bjp-19567	18	7	the	the	DET
bjp-19567	18	8	cell	cell	NOUN
bjp-19567	18	9	inhibitory	inhibitory	ADJ
bjp-19567	18	10	effect	effect	NOUN
bjp-19567	18	11	was	be	AUX
bjp-19567	18	12	regulated	regulate	VERB
bjp-19567	18	13	by	by	ADP
bjp-19567	18	14	the	the	DET
bjp-19567	18	15	activation	activation	NOUN
bjp-19567	18	16	of	of	ADP
bjp-19567	18	17	erk	erk	NOUN
bjp-19567	18	18	signaling	signal	VERB
bjp-19567	18	19	pathway	pathway	NOUN
bjp-19567	18	20	while	while	SCONJ
bjp-19567	18	21	akt	akt	PROPN
bjp-19567	18	22	signaling	signal	VERB
bjp-19567	18	23	pathway	pathway	NOUN
bjp-19567	18	24	was	be	AUX
bjp-19567	18	25	down	down	ADV
bjp-19567	18	26	regulated	regulate	VERB
bjp-19567	18	27	in	in	ADP
bjp-19567	18	28	saos-2	saos-2	NUM
bjp-19567	18	29	cells	cell	NOUN
bjp-19567	18	30	after	after	ADP
bjp-19567	18	31	24	24	NUM
bjp-19567	18	32	hours	hour	NOUN
bjp-19567	18	33	of	of	ADP
bjp-19567	18	34	nobiletin	nobiletin	NOUN
bjp-19567	18	35	treatment	treatment	NOUN
bjp-19567	18	36	.	.	PUNCT
bjp-19567	19	1	article	article	NOUN
bjp-19567	19	2	info	info	NOUN
bjp-19567	19	3	received	receive	VERB
bjp-19567	19	4	:	:	PUNCT
bjp-19567	19	5	17	17	NUM
bjp-19567	19	6	july	july	PROPN
bjp-19567	19	7	2014	2014	NUM
bjp-19567	19	8	accepted	accept	VERB
bjp-19567	19	9	:	:	PUNCT
bjp-19567	19	10	27	27	NUM
bjp-19567	19	11	july	july	PROPN
bjp-19567	19	12	2014	2014	NUM
bjp-19567	19	13	available	available	ADJ
bjp-19567	19	14	online	online	NOUN
bjp-19567	19	15	:	:	PUNCT
bjp-19567	19	16	3	3	NUM
bjp-19567	19	17	september	september	PROPN
bjp-19567	19	18	2014	2014	NUM
bjp-19567	19	19	doi	doi	NOUN
bjp-19567	19	20	:	:	PUNCT
bjp-19567	19	21	10.3329	10.3329	NUM
bjp-19567	19	22	/	/	SYM
bjp-19567	19	23	bjp.v9i3.19567	bjp.v9i3.19567	PROPN
bjp-19567	19	24	cite	cite	VERB
bjp-19567	19	25	this	this	DET
bjp-19567	19	26	article	article	NOUN
bjp-19567	19	27	:	:	PUNCT
bjp-19567	19	28	niu	niu	PROPN
bjp-19567	19	29	fw	fw	PROPN
bjp-19567	19	30	,	,	PUNCT
bjp-19567	19	31	zhang	zhang	PROPN
bjp-19567	19	32	yj	yj	PROPN
bjp-19567	19	33	,	,	PUNCT
bjp-19567	19	34	li	li	PROPN
bjp-19567	19	35	k	k	PROPN
bjp-19567	19	36	,	,	PUNCT
bjp-19567	19	37	zhang	zhang	PROPN
bjp-19567	19	38	ms	ms	PROPN
bjp-19567	19	39	.	.	PROPN
bjp-19567	19	40	nobiletin	nobiletin	PROPN
bjp-19567	19	41	acts	act	NOUN
bjp-19567	19	42	as	as	ADP
bjp-19567	19	43	a	a	DET
bjp-19567	19	44	potential	potential	ADJ
bjp-19567	19	45	anticancer	anticancer	NOUN
bjp-19567	19	46	agent	agent	NOUN
bjp-19567	19	47	against	against	ADP
bjp-19567	19	48	osteosarcoma	osteosarcoma	NOUN
bjp-19567	19	49	by	by	ADP
bjp-19567	19	50	regulating	regulate	VERB
bjp-19567	19	51	erk	erk	PROPN
bjp-19567	19	52	and	and	CCONJ
bjp-19567	19	53	akt	akt	PROPN
bjp-19567	19	54	signaling	signal	VERB
bjp-19567	19	55	pathways	pathway	NOUN
bjp-19567	19	56	.	.	PUNCT
bjp-19567	20	1	bangladesh	bangladesh	PROPN
bjp-19567	20	2	j	j	PROPN
bjp-19567	20	3	pharmacol	pharmacol	PROPN
bjp-19567	20	4	.	.	PUNCT
bjp-19567	20	5	2014	2014	NUM
bjp-19567	20	6	;	;	PUNCT
bjp-19567	20	7	9	9	NUM
bjp-19567	20	8	:	:	SYM
bjp-19567	20	9	00	00	NUM
bjp-19567	20	10	-	-	SYM
bjp-19567	20	11	00	00	NUM
bjp-19567	20	12	.	.	PUNCT
bjp-19567	21	1	this	this	DET
bjp-19567	21	2	work	work	NOUN
bjp-19567	21	3	is	be	AUX
bjp-19567	21	4	licensed	license	VERB
bjp-19567	21	5	under	under	ADP
bjp-19567	21	6	a	a	DET
bjp-19567	21	7	creative	creative	ADJ
bjp-19567	21	8	commons	common	NOUN
bjp-19567	21	9	attribution	attribution	NOUN
bjp-19567	21	10	3.0	3.0	NUM
bjp-19567	21	11	license	license	NOUN
bjp-19567	21	12	.	.	PUNCT
bjp-19567	22	1	you	you	PRON
bjp-19567	22	2	are	be	AUX
bjp-19567	22	3	free	free	ADJ
bjp-19567	22	4	to	to	PART
bjp-19567	22	5	copy	copy	VERB
bjp-19567	22	6	,	,	PUNCT
bjp-19567	22	7	distribute	distribute	VERB
bjp-19567	22	8	and	and	CCONJ
bjp-19567	22	9	perform	perform	VERB
bjp-19567	22	10	the	the	DET
bjp-19567	22	11	work	work	NOUN
bjp-19567	22	12	.	.	PUNCT
bjp-19567	23	1	you	you	PRON
bjp-19567	23	2	must	must	AUX
bjp-19567	23	3	attribute	attribute	VERB
bjp-19567	23	4	the	the	DET
bjp-19567	23	5	work	work	NOUN
bjp-19567	23	6	in	in	ADP
bjp-19567	23	7	the	the	DET
bjp-19567	23	8	manner	manner	NOUN
bjp-19567	23	9	specified	specify	VERB
bjp-19567	23	10	by	by	ADP
bjp-19567	23	11	the	the	DET
bjp-19567	23	12	author	author	NOUN
bjp-19567	23	13	or	or	CCONJ
bjp-19567	23	14	licensor	licensor	NOUN
bjp-19567	23	15	.	.	PUNCT
bjp-19567	24	1	nobiletin	nobiletin	NOUN
bjp-19567	24	2	acts	act	NOUN
bjp-19567	24	3	as	as	ADP
bjp-19567	24	4	a	a	DET
bjp-19567	24	5	potential	potential	ADJ
bjp-19567	24	6	anti	anti	ADJ
bjp-19567	24	7	-	-	ADJ
bjp-19567	24	8	cancer	cancer	ADJ
bjp-19567	24	9	agent	agent	NOUN
bjp-19567	24	10	against	against	ADP
bjp-19567	24	11	osteosarcoma	osteosarcoma	NOUN
bjp-19567	24	12	by	by	ADP
bjp-19567	24	13	regulating	regulate	VERB
bjp-19567	24	14	erk	erk	PROPN
bjp-19567	24	15	and	and	CCONJ
bjp-19567	24	16	akt	akt	PROPN
bjp-19567	24	17	signaling	signal	VERB
bjp-19567	24	18	pathways	pathway	NOUN
bjp-19567	24	19	fu	fu	PROPN
bjp-19567	24	20	wen	wen	PROPN
bjp-19567	24	21	niu1	niu1	PROPN
bjp-19567	24	22	,	,	PUNCT
bjp-19567	24	23	yong	yong	PROPN
bjp-19567	24	24	jie	jie	PROPN
bjp-19567	25	1	zhang2	zhang2	PROPN
bjp-19567	25	2	,	,	PUNCT
bjp-19567	25	3	kun	kun	PROPN
bjp-19567	25	4	li3,4	li3,4	PROPN
bjp-19567	25	5	and	and	CCONJ
bjp-19567	25	6	mao	mao	PROPN
bjp-19567	25	7	shu	shu	PROPN
bjp-19567	25	8	zhang1	zhang1	PROPN
bjp-19567	26	1	1department	1department	NUM
bjp-19567	26	2	of	of	ADP
bjp-19567	26	3	orthopedics	orthopedic	NOUN
bjp-19567	26	4	,	,	PUNCT
bjp-19567	26	5	jining	jine	VERB
bjp-19567	26	6	no.1	no.1	ADJ
bjp-19567	26	7	people	people	NOUN
bjp-19567	26	8	’s	’s	PART
bjp-19567	26	9	hospital	hospital	NOUN
bjp-19567	26	10	in	in	ADP
bjp-19567	26	11	shandong	shandong	PROPN
bjp-19567	26	12	province	province	PROPN
bjp-19567	26	13	,	,	PUNCT
bjp-19567	26	14	p.r	p.r	PROPN
bjp-19567	26	15	.	.	PROPN
bjp-19567	26	16	china	china	PROPN
bjp-19567	26	17	;	;	PUNCT
bjp-19567	27	1	2department	2department	NUM
bjp-19567	27	2	of	of	ADP
bjp-19567	27	3	orthopedics	orthopedic	NOUN
bjp-19567	27	4	,	,	PUNCT
bjp-19567	27	5	jinxiang	jinxiang	PROPN
bjp-19567	27	6	people	people	NOUN
bjp-19567	27	7	’s	’s	PART
bjp-19567	27	8	hospital	hospital	NOUN
bjp-19567	27	9	in	in	ADP
bjp-19567	27	10	shandong	shandong	PROPN
bjp-19567	27	11	province	province	PROPN
bjp-19567	27	12	,	,	PUNCT
bjp-19567	27	13	p.r	p.r	PROPN
bjp-19567	27	14	.	.	PROPN
bjp-19567	27	15	china	china	PROPN
bjp-19567	27	16	;	;	PUNCT
bjp-19567	27	17	3department	3department	NUM
bjp-19567	27	18	of	of	ADP
bjp-19567	27	19	gynecology	gynecology	NOUN
bjp-19567	27	20	and	and	CCONJ
bjp-19567	27	21	obstetrics	obstetric	NOUN
bjp-19567	27	22	,	,	PUNCT
bjp-19567	27	23	affiliated	affiliated	ADJ
bjp-19567	27	24	hospital	hospital	NOUN
bjp-19567	27	25	of	of	ADP
bjp-19567	27	26	shandong	shandong	PROPN
bjp-19567	27	27	academy	academy	PROPN
bjp-19567	27	28	of	of	ADP
bjp-19567	27	29	medical	medical	PROPN
bjp-19567	27	30	sciences	sciences	PROPN
bjp-19567	27	31	,	,	PUNCT
bjp-19567	27	32	p.r	p.r	PROPN
bjp-19567	27	33	.	.	PROPN
bjp-19567	27	34	china	china	PROPN
bjp-19567	27	35	;	;	PUNCT
bjp-19567	27	36	4department	4department	NUM
bjp-19567	27	37	of	of	ADP
bjp-19567	27	38	gynecology	gynecology	NOUN
bjp-19567	27	39	and	and	CCONJ
bjp-19567	27	40	obstetrics	obstetric	NOUN
bjp-19567	27	41	,	,	PUNCT
bjp-19567	27	42	shandong	shandong	PROPN
bjp-19567	27	43	academy	academy	PROPN
bjp-19567	27	44	of	of	ADP
bjp-19567	27	45	medical	medical	PROPN
bjp-19567	27	46	sciences	sciences	PROPN
bjp-19567	27	47	,	,	PUNCT
bjp-19567	27	48	p.r	p.r	PROPN
bjp-19567	27	49	.	.	PROPN
bjp-19567	27	50	china	china	PROPN
bjp-19567	27	51	.	.	PUNCT
bjp-19567	28	1	also	also	ADV
bjp-19567	28	2	rarely	rarely	ADV
bjp-19567	28	3	reported	report	VERB
bjp-19567	28	4	.	.	PUNCT
bjp-19567	29	1	therefore	therefore	ADV
bjp-19567	29	2	,	,	PUNCT
bjp-19567	29	3	this	this	DET
bjp-19567	29	4	study	study	NOUN
bjp-19567	29	5	aims	aim	VERB
bjp-19567	29	6	to	to	PART
bjp-19567	29	7	characterize	characterize	VERB
bjp-19567	29	8	the	the	DET
bjp-19567	29	9	inhibitory	inhibitory	ADJ
bjp-19567	29	10	effect	effect	NOUN
bjp-19567	29	11	of	of	ADP
bjp-19567	29	12	nobiletin	nobiletin	NOUN
bjp-19567	29	13	on	on	ADP
bjp-19567	29	14	osteosarcoma	osteosarcoma	ADJ
bjp-19567	29	15	cell	cell	NOUN
bjp-19567	29	16	line	line	NOUN
bjp-19567	29	17	and	and	CCONJ
bjp-19567	29	18	delineate	delineate	VERB
bjp-19567	29	19	the	the	DET
bjp-19567	29	20	signaling	signal	VERB
bjp-19567	29	21	mechanism	mechanism	NOUN
bjp-19567	29	22	involved	involve	VERB
bjp-19567	29	23	.	.	PUNCT
bjp-19567	30	1	materials	material	NOUN
bjp-19567	30	2	and	and	CCONJ
bjp-19567	30	3	methods	method	NOUN
bjp-19567	30	4	materials	material	NOUN
bjp-19567	30	5	nobiletin	nobiletin	NOUN
bjp-19567	30	6	(	(	PUNCT
bjp-19567	30	7	purity	purity	NOUN
bjp-19567	30	8	≥98	≥98	NOUN
bjp-19567	30	9	%	%	NOUN
bjp-19567	30	10	)	)	PUNCT
bjp-19567	30	11	,	,	PUNCT
bjp-19567	30	12	3-(4,5	3-(4,5	PROPN
bjp-19567	30	13	-	-	PUNCT
bjp-19567	30	14	dimethlthiazol-2	dimethlthiazol-2	NUM
bjp-19567	30	15	-	-	PUNCT
bjp-19567	30	16	yl)-2,5diphenyl	yl)-2,5diphenyl	NOUN
bjp-19567	30	17	-	-	NOUN
bjp-19567	30	18	tetrazoliumbromide	tetrazoliumbromide	NOUN
bjp-19567	30	19	(	(	PUNCT
bjp-19567	30	20	mtt	mtt	NOUN
bjp-19567	30	21	)	)	PUNCT
bjp-19567	30	22	,	,	PUNCT
bjp-19567	30	23	bovine	bovine	NOUN
bjp-19567	30	24	serum	serum	NOUN
bjp-19567	30	25	albumin	albumin	PROPN
bjp-19567	30	26	(	(	PUNCT
bjp-19567	30	27	bsa	bsa	PROPN
bjp-19567	30	28	)	)	PUNCT
bjp-19567	30	29	,	,	PUNCT
bjp-19567	30	30	fetal	fetal	ADJ
bjp-19567	30	31	bovine	bovine	NOUN
bjp-19567	30	32	serum	serum	NOUN
bjp-19567	30	33	(	(	PUNCT
bjp-19567	30	34	fbs	fbs	PROPN
bjp-19567	30	35	)	)	PUNCT
bjp-19567	30	36	,	,	PUNCT
bjp-19567	30	37	phosphate	phosphate	ADJ
bjp-19567	30	38	buffer	buffer	NOUN
bjp-19567	30	39	saline	saline	NOUN
bjp-19567	30	40	(	(	PUNCT
bjp-19567	30	41	pbs	pbs	PROPN
bjp-19567	30	42	)	)	PUNCT
bjp-19567	30	43	,	,	PUNCT
bjp-19567	30	44	dmso	dmso	NOUN
bjp-19567	30	45	,	,	PUNCT
bjp-19567	30	46	sodium	sodium	NOUN
bjp-19567	30	47	dodecyl	dodecyl	NOUN
bjp-19567	30	48	sulfate	sulfate	NOUN
bjp-19567	30	49	(	(	PUNCT
bjp-19567	30	50	sds	sds	PROPN
bjp-19567	30	51	)	)	PUNCT
bjp-19567	30	52	,	,	PUNCT
bjp-19567	30	53	edta	edta	NOUN
bjp-19567	30	54	,	,	PUNCT
bjp-19567	30	55	tris	tris	NOUN
bjp-19567	30	56	-	-	PUNCT
bjp-19567	30	57	hcl	hcl	NOUN
bjp-19567	30	58	,	,	PUNCT
bjp-19567	30	59	was	be	AUX
bjp-19567	30	60	purchased	purchase	VERB
bjp-19567	30	61	from	from	ADP
bjp-19567	30	62	sigmaaldrich	sigmaaldrich	PROPN
bjp-19567	30	63	(	(	PUNCT
bjp-19567	30	64	usa	usa	PROPN
bjp-19567	30	65	)	)	PUNCT
bjp-19567	30	66	.	.	PUNCT
bjp-19567	31	1	cytotoxicity	cytotoxicity	NOUN
bjp-19567	31	2	detection	detection	NOUN
bjp-19567	31	3	kit	kit	NOUN
bjp-19567	31	4	was	be	AUX
bjp-19567	31	5	purchased	purchase	VERB
bjp-19567	31	6	from	from	ADP
bjp-19567	31	7	takara	takara	PROPN
bjp-19567	31	8	bio	bio	PROPN
bjp-19567	31	9	inc	inc	PROPN
bjp-19567	31	10	.	.	PROPN
bjp-19567	31	11	,	,	PUNCT
bjp-19567	31	12	shiga	shiga	PROPN
bjp-19567	31	13	,	,	PUNCT
bjp-19567	31	14	japan	japan	PROPN
bjp-19567	31	15	.	.	PUNCT
bjp-19567	32	1	caspase-3	caspase-3	NUM
bjp-19567	32	2	colorimetric	colorimetric	ADJ
bjp-19567	32	3	assay	assay	NOUN
bjp-19567	32	4	kit	kit	NOUN
bjp-19567	32	5	and	and	CCONJ
bjp-19567	32	6	caspase-9	caspase-9	NUM
bjp-19567	32	7	colorimetric	colorimetric	ADJ
bjp-19567	32	8	assay	assay	NOUN
bjp-19567	32	9	kit	kit	NOUN
bjp-19567	32	10	was	be	AUX
bjp-19567	32	11	obtained	obtain	VERB
bjp-19567	32	12	from	from	ADP
bjp-19567	32	13	biovision	biovision	NOUN
bjp-19567	32	14	,	,	PUNCT
bjp-19567	32	15	inc	inc	PROPN
bjp-19567	32	16	.	.	PROPN
bjp-19567	32	17	protein	protein	NOUN
bjp-19567	32	18	assay	assay	VERB
bjp-19567	32	19	reagent	reagent	NOUN
bjp-19567	32	20	was	be	AUX
bjp-19567	32	21	purchased	purchase	VERB
bjp-19567	32	22	from	from	ADP
bjp-19567	32	23	bio	bio	ADJ
bjp-19567	32	24	-	-	ADJ
bjp-19567	32	25	rad	rad	ADJ
bjp-19567	32	26	laboratories	laboratory	NOUN
bjp-19567	32	27	(	(	PUNCT
bjp-19567	32	28	hercules	hercules	PROPN
bjp-19567	32	29	,	,	PUNCT
bjp-19567	32	30	usa	usa	PROPN
bjp-19567	32	31	)	)	PUNCT
bjp-19567	32	32	.	.	PUNCT
bjp-19567	33	1	antibody	antibody	NOUN
bjp-19567	33	2	against	against	ADP
bjp-19567	33	3	akt	akt	PROPN
bjp-19567	33	4	,	,	PUNCT
bjp-19567	33	5	erk	erk	PROPN
bjp-19567	33	6	,	,	PUNCT
bjp-19567	33	7	catenin	catenin	ADJ
bjp-19567	33	8	and	and	CCONJ
bjp-19567	33	9	-actin	-actin	PROPN
bjp-19567	33	10	were	be	AUX
bjp-19567	33	11	purchased	purchase	VERB
bjp-19567	33	12	from	from	ADP
bjp-19567	33	13	cell	cell	NOUN
bjp-19567	33	14	signaling	signal	VERB
bjp-19567	33	15	technology	technology	NOUN
bjp-19567	33	16	,	,	PUNCT
bjp-19567	33	17	danvers	danver	NOUN
bjp-19567	33	18	,	,	PUNCT
bjp-19567	33	19	ma	ma	PROPN
bjp-19567	33	20	.	.	PROPN
bjp-19567	33	21	cell	cell	PROPN
bjp-19567	33	22	culture	culture	PROPN
bjp-19567	33	23	human	human	ADJ
bjp-19567	33	24	osteosarcoma	osteosarcoma	ADJ
bjp-19567	33	25	cell	cell	NOUN
bjp-19567	33	26	line	line	NOUN
bjp-19567	33	27	,	,	PUNCT
bjp-19567	33	28	saos-2	saos-2	NUM
bjp-19567	33	29	,	,	PUNCT
bjp-19567	33	30	was	be	AUX
bjp-19567	33	31	cultured	cultured	ADJ
bjp-19567	33	32	in	in	ADP
bjp-19567	33	33	10	10	NUM
bjp-19567	33	34	%	%	NOUN
bjp-19567	33	35	fetal	fetal	ADJ
bjp-19567	33	36	bovine	bovine	NOUN
bjp-19567	33	37	serum	serum	NOUN
bjp-19567	33	38	(	(	PUNCT
bjp-19567	33	39	fbs	fbs	PROPN
bjp-19567	33	40	)	)	PUNCT
bjp-19567	33	41	,	,	PUNCT
bjp-19567	33	42	100	100	NUM
bjp-19567	33	43	u	u	NOUN
bjp-19567	33	44	/	/	SYM
bjp-19567	33	45	ml	ml	NOUN
bjp-19567	33	46	penicillin	penicillin	NOUN
bjp-19567	33	47	and	and	CCONJ
bjp-19567	33	48	100	100	NUM
bjp-19567	33	49	µg	µg	ADJ
bjp-19567	33	50	/	/	SYM
bjp-19567	33	51	ml	ml	NOUN
bjp-19567	33	52	streptomycin	streptomycin	PROPN
bjp-19567	33	53	(	(	PUNCT
bjp-19567	33	54	lonza	lonza	PROPN
bjp-19567	33	55	,	,	PUNCT
bjp-19567	33	56	switzerland	switzerland	PROPN
bjp-19567	33	57	)	)	PUNCT
bjp-19567	33	58	supplemented	supplement	VERB
bjp-19567	33	59	-mem	-mem	ADJ
bjp-19567	33	60	medium	medium	ADJ
bjp-19567	33	61	(	(	PUNCT
bjp-19567	33	62	invitrogen	invitrogen	PROPN
bjp-19567	33	63	,	,	PUNCT
bjp-19567	33	64	usa	usa	PROPN
bjp-19567	33	65	)	)	PUNCT
bjp-19567	33	66	.	.	PUNCT
bjp-19567	34	1	the	the	DET
bjp-19567	34	2	cells	cell	NOUN
bjp-19567	34	3	were	be	AUX
bjp-19567	34	4	grown	grow	VERB
bjp-19567	34	5	at	at	ADP
bjp-19567	34	6	37	37	NUM
bjp-19567	34	7	°	°	ADP
bjp-19567	34	8	c	c	NOUN
bjp-19567	34	9	in	in	ADP
bjp-19567	34	10	humidified	humidified	ADJ
bjp-19567	34	11	chamber	chamber	NOUN
bjp-19567	34	12	with	with	ADP
bjp-19567	34	13	95%air	95%air	NOUN
bjp-19567	34	14	and	and	CCONJ
bjp-19567	34	15	5%co2	5%co2	NUM
bjp-19567	34	16	.	.	PUNCT
bjp-19567	35	1	the	the	DET
bjp-19567	35	2	confluence	confluence	NOUN
bjp-19567	35	3	level	level	NOUN
bjp-19567	35	4	of	of	ADP
bjp-19567	35	5	saos-2	saos-2	NUM
bjp-19567	35	6	cell	cell	NOUN
bjp-19567	35	7	line	line	NOUN
bjp-19567	35	8	was	be	AUX
bjp-19567	35	9	maintained	maintain	VERB
bjp-19567	35	10	at	at	ADP
bjp-19567	35	11	70	70	NUM
bjp-19567	35	12	-	-	SYM
bjp-19567	35	13	80	80	NUM
bjp-19567	35	14	%	%	NOUN
bjp-19567	35	15	.	.	PUNCT
bjp-19567	36	1	saos-2	saos-2	NUM
bjp-19567	36	2	cell	cell	NOUN
bjp-19567	36	3	line	line	NOUN
bjp-19567	36	4	was	be	AUX
bjp-19567	36	5	chosen	choose	VERB
bjp-19567	36	6	because	because	SCONJ
bjp-19567	36	7	it	it	PRON
bjp-19567	36	8	is	be	AUX
bjp-19567	36	9	known	know	VERB
bjp-19567	36	10	to	to	PART
bjp-19567	36	11	be	be	AUX
bjp-19567	36	12	depicting	depict	VERB
bjp-19567	36	13	osteosarcoma	osteosarcoma	ADJ
bjp-19567	36	14	characteristics	characteristic	NOUN
bjp-19567	36	15	and	and	CCONJ
bjp-19567	36	16	is	be	AUX
bjp-19567	36	17	being	be	AUX
bjp-19567	36	18	widely	widely	ADV
bjp-19567	36	19	used	use	VERB
bjp-19567	36	20	for	for	ADP
bjp-19567	36	21	cell	cell	NOUN
bjp-19567	36	22	proliferation	proliferation	NOUN
bjp-19567	36	23	and	and	CCONJ
bjp-19567	36	24	differentiation	differentiation	NOUN
bjp-19567	36	25	studies	study	NOUN
bjp-19567	36	26	(	(	PUNCT
bjp-19567	36	27	hunt	hunt	NOUN
bjp-19567	36	28	et	et	NOUN
bjp-19567	36	29	al	al	PROPN
bjp-19567	36	30	.	.	PROPN
bjp-19567	36	31	,	,	PUNCT
bjp-19567	36	32	1996	1996	NUM
bjp-19567	36	33	)	)	PUNCT
bjp-19567	36	34	.	.	PUNCT
bjp-19567	37	1	cell	cell	NOUN
bjp-19567	37	2	viability	viability	NOUN
bjp-19567	37	3	assay	assay	PROPN
bjp-19567	37	4	(	(	PUNCT
bjp-19567	37	5	mtt	mtt	NOUN
bjp-19567	37	6	assay	assay	VERB
bjp-19567	37	7	)	)	PUNCT
bjp-19567	37	8	the	the	DET
bjp-19567	37	9	anti	anti	ADJ
bjp-19567	37	10	-	-	ADJ
bjp-19567	37	11	proliferative	proliferative	ADJ
bjp-19567	37	12	effect	effect	NOUN
bjp-19567	37	13	of	of	ADP
bjp-19567	37	14	nobiletin	nobiletin	NOUN
bjp-19567	37	15	on	on	ADP
bjp-19567	37	16	saos-2	saos-2	NUM
bjp-19567	37	17	cell	cell	NOUN
bjp-19567	37	18	line	line	NOUN
bjp-19567	37	19	was	be	AUX
bjp-19567	37	20	performed	perform	VERB
bjp-19567	37	21	by	by	ADP
bjp-19567	37	22	mtt	mtt	NOUN
bjp-19567	37	23	assay	assay	NOUN
bjp-19567	37	24	.	.	PUNCT
bjp-19567	38	1	cell	cell	NOUN
bjp-19567	38	2	viability	viability	NOUN
bjp-19567	38	3	assay	assay	NOUN
bjp-19567	38	4	was	be	AUX
bjp-19567	38	5	achieved	achieve	VERB
bjp-19567	38	6	by	by	ADP
bjp-19567	38	7	plating	plate	VERB
bjp-19567	38	8	2	2	NUM
bjp-19567	38	9	x	x	SYM
bjp-19567	38	10	104	104	NUM
bjp-19567	38	11	cells	cell	NOUN
bjp-19567	38	12	/	/	SYM
bjp-19567	38	13	well	well	ADV
bjp-19567	38	14	in	in	ADP
bjp-19567	38	15	96	96	NUM
bjp-19567	38	16	well	well	ADJ
bjp-19567	38	17	plate	plate	NOUN
bjp-19567	38	18	at	at	ADP
bjp-19567	38	19	37	37	NUM
bjp-19567	38	20	°	°	ADP
bjp-19567	38	21	c	c	NOUN
bjp-19567	38	22	for	for	ADP
bjp-19567	38	23	24	24	NUM
bjp-19567	38	24	hours	hour	NOUN
bjp-19567	38	25	followed	follow	VERB
bjp-19567	38	26	by	by	ADP
bjp-19567	38	27	treatment	treatment	NOUN
bjp-19567	38	28	with	with	ADP
bjp-19567	38	29	different	different	ADJ
bjp-19567	38	30	doses	dose	NOUN
bjp-19567	38	31	of	of	ADP
bjp-19567	38	32	nobiletin	nobiletin	NOUN
bjp-19567	38	33	(	(	PUNCT
bjp-19567	38	34	0.5	0.5	NUM
bjp-19567	38	35	,	,	PUNCT
bjp-19567	38	36	1	1	NUM
bjp-19567	38	37	,	,	PUNCT
bjp-19567	38	38	2.5	2.5	NUM
bjp-19567	38	39	,	,	PUNCT
bjp-19567	38	40	5	5	NUM
bjp-19567	38	41	and	and	CCONJ
bjp-19567	38	42	10	10	NUM
bjp-19567	38	43	µm	µm	NUM
bjp-19567	38	44	)	)	PUNCT
bjp-19567	38	45	.	.	PUNCT
bjp-19567	39	1	after	after	ADP
bjp-19567	39	2	incubating	incubate	VERB
bjp-19567	39	3	the	the	DET
bjp-19567	39	4	cells	cell	NOUN
bjp-19567	39	5	at	at	ADP
bjp-19567	39	6	predetermined	predetermine	VERB
bjp-19567	39	7	time	time	NOUN
bjp-19567	39	8	points	point	NOUN
bjp-19567	39	9	i.e.	i.e.	X
bjp-19567	39	10	24	24	NUM
bjp-19567	39	11	,	,	PUNCT
bjp-19567	39	12	48	48	NUM
bjp-19567	39	13	and	and	CCONJ
bjp-19567	39	14	72	72	NUM
bjp-19567	39	15	hours	hour	NOUN
bjp-19567	39	16	,	,	PUNCT
bjp-19567	39	17	3-(4,5	3-(4,5	PROPN
bjp-19567	39	18	-	-	PUNCT
bjp-19567	39	19	dimethlthiazol-2	dimethlthiazol-2	NUM
bjp-19567	39	20	-	-	PUNCT
bjp-19567	39	21	yl)-2,5diphenyl	yl)-2,5diphenyl	NOUN
bjp-19567	39	22	-	-	NOUN
bjp-19567	39	23	tetrazoliumbromide	tetrazoliumbromide	NOUN
bjp-19567	39	24	(	(	PUNCT
bjp-19567	39	25	mtt	mtt	NOUN
bjp-19567	39	26	)	)	PUNCT
bjp-19567	39	27	solution	solution	NOUN
bjp-19567	39	28	(	(	PUNCT
bjp-19567	39	29	20	20	NUM
bjp-19567	39	30	µl	µl	NOUN
bjp-19567	39	31	)	)	PUNCT
bjp-19567	39	32	was	be	AUX
bjp-19567	39	33	added	add	VERB
bjp-19567	39	34	in	in	ADP
bjp-19567	39	35	each	each	DET
bjp-19567	39	36	well	well	NOUN
bjp-19567	39	37	and	and	CCONJ
bjp-19567	39	38	again	again	ADV
bjp-19567	39	39	incubated	incubate	VERB
bjp-19567	39	40	for	for	ADP
bjp-19567	39	41	3	3	NUM
bjp-19567	39	42	hours	hour	NOUN
bjp-19567	39	43	at	at	ADP
bjp-19567	39	44	37	37	NUM
bjp-19567	39	45	°	°	ADP
bjp-19567	39	46	c	c	NOUN
bjp-19567	39	47	to	to	PART
bjp-19567	39	48	facilitate	facilitate	VERB
bjp-19567	39	49	the	the	DET
bjp-19567	39	50	production	production	NOUN
bjp-19567	39	51	of	of	ADP
bjp-19567	39	52	mtt	mtt	NOUN
bjp-19567	39	53	formazan	formazan	NOUN
bjp-19567	39	54	by	by	ADP
bjp-19567	39	55	mitochondrial	mitochondrial	ADJ
bjp-19567	39	56	succinate	succinate	NOUN
bjp-19567	39	57	.	.	PUNCT
bjp-19567	40	1	after	after	ADP
bjp-19567	40	2	removal	removal	NOUN
bjp-19567	40	3	of	of	ADP
bjp-19567	40	4	supernatant	supernatant	NOUN
bjp-19567	40	5	,	,	PUNCT
bjp-19567	40	6	dmso	dmso	NOUN
bjp-19567	40	7	was	be	AUX
bjp-19567	40	8	added	add	VERB
bjp-19567	40	9	to	to	ADP
bjp-19567	40	10	each	each	DET
bjp-19567	40	11	well	well	NOUN
bjp-19567	40	12	to	to	PART
bjp-19567	40	13	dissolve	dissolve	VERB
bjp-19567	40	14	mtt	mtt	NOUN
bjp-19567	40	15	formazan	formazan	NOUN
bjp-19567	40	16	.	.	PUNCT
bjp-19567	41	1	cell	cell	NOUN
bjp-19567	41	2	viability	viability	NOUN
bjp-19567	41	3	was	be	AUX
bjp-19567	41	4	calculated	calculate	VERB
bjp-19567	41	5	after	after	ADP
bjp-19567	41	6	measuring	measure	VERB
bjp-19567	41	7	optical	optical	ADJ
bjp-19567	41	8	density	density	NOUN
bjp-19567	41	9	using	use	VERB
bjp-19567	41	10	uv	uv	NOUN
bjp-19567	41	11	-	-	PUNCT
bjp-19567	41	12	vis	vis	X
bjp-19567	41	13	spectrophotometer	spectrophotometer	NOUN
bjp-19567	41	14	at	at	ADP
bjp-19567	41	15	570	570	NUM
bjp-19567	41	16	nm	nm	ADJ
bjp-19567	41	17	wave	wave	NOUN
bjp-19567	41	18	length	length	NOUN
bjp-19567	41	19	.	.	PUNCT
bjp-19567	42	1	each	each	DET
bjp-19567	42	2	experiment	experiment	NOUN
bjp-19567	42	3	set	set	VERB
bjp-19567	42	4	was	be	AUX
bjp-19567	42	5	done	do	VERB
bjp-19567	42	6	in	in	ADP
bjp-19567	42	7	triplicate	triplicate	NOUN
bjp-19567	42	8	for	for	ADP
bjp-19567	42	9	accuracy	accuracy	NOUN
bjp-19567	42	10	and	and	CCONJ
bjp-19567	42	11	data	datum	NOUN
bjp-19567	42	12	are	be	AUX
bjp-19567	42	13	expressed	express	VERB
bjp-19567	42	14	as	as	ADP
bjp-19567	42	15	mean	mean	NOUN
bjp-19567	42	16	±	±	NUM
bjp-19567	42	17	sd	sd	NOUN
bjp-19567	42	18	.	.	PUNCT
bjp-19567	43	1	ldh	ldh	PROPN
bjp-19567	43	2	assay	assay	PROPN
bjp-19567	43	3	cell	cell	NOUN
bjp-19567	43	4	cytotoxicity	cytotoxicity	NOUN
bjp-19567	43	5	was	be	AUX
bjp-19567	43	6	determined	determine	VERB
bjp-19567	43	7	by	by	ADP
bjp-19567	43	8	evaluating	evaluate	VERB
bjp-19567	43	9	the	the	DET
bjp-19567	43	10	release	release	NOUN
bjp-19567	43	11	of	of	ADP
bjp-19567	43	12	lactate	lactate	NOUN
bjp-19567	43	13	dehydrogenase	dehydrogenase	NOUN
bjp-19567	43	14	enzyme	enzyme	NOUN
bjp-19567	43	15	from	from	ADP
bjp-19567	43	16	the	the	DET
bjp-19567	43	17	damaged	damage	VERB
bjp-19567	43	18	cells	cell	NOUN
bjp-19567	43	19	using	use	VERB
bjp-19567	43	20	cytotoxicity	cytotoxicity	NOUN
bjp-19567	43	21	detection	detection	NOUN
bjp-19567	43	22	kit	kit	NOUN
bjp-19567	43	23	according	accord	VERB
bjp-19567	43	24	to	to	ADP
bjp-19567	43	25	manufacturer	manufacturer	PROPN
bjp-19567	43	26	’s	’s	PART
bjp-19567	43	27	protocol	protocol	NOUN
bjp-19567	43	28	.	.	PUNCT
bjp-19567	44	1	lactate	lactate	NOUN
bjp-19567	44	2	dehydrogenase	dehydrogenase	NOUN
bjp-19567	44	3	enzyme	enzyme	NOUN
bjp-19567	44	4	is	be	AUX
bjp-19567	44	5	found	find	VERB
bjp-19567	44	6	in	in	ADP
bjp-19567	44	7	the	the	DET
bjp-19567	44	8	cytoplasm	cytoplasm	NOUN
bjp-19567	44	9	of	of	ADP
bjp-19567	44	10	cells	cell	NOUN
bjp-19567	44	11	and	and	CCONJ
bjp-19567	44	12	is	be	AUX
bjp-19567	44	13	commonly	commonly	ADV
bjp-19567	44	14	used	use	VERB
bjp-19567	44	15	as	as	ADP
bjp-19567	44	16	a	a	DET
bjp-19567	44	17	marker	marker	NOUN
bjp-19567	44	18	to	to	PART
bjp-19567	44	19	detect	detect	VERB
bjp-19567	44	20	cell	cell	NOUN
bjp-19567	44	21	membrane	membrane	NOUN
bjp-19567	44	22	damage	damage	NOUN
bjp-19567	44	23	(	(	PUNCT
bjp-19567	44	24	legrand	legrand	PROPN
bjp-19567	44	25	et	et	PROPN
bjp-19567	44	26	al	al	PROPN
bjp-19567	44	27	.	.	PROPN
bjp-19567	44	28	,	,	PUNCT
bjp-19567	44	29	1992	1992	NUM
bjp-19567	44	30	)	)	PUNCT
bjp-19567	44	31	.	.	PUNCT
bjp-19567	45	1	briefly	briefly	NOUN
bjp-19567	45	2	,	,	PUNCT
bjp-19567	45	3	saos-2	saos-2	NUM
bjp-19567	45	4	cells	cell	NOUN
bjp-19567	45	5	were	be	AUX
bjp-19567	45	6	seeded	seed	VERB
bjp-19567	45	7	in	in	ADP
bjp-19567	45	8	96	96	NUM
bjp-19567	45	9	wells	well	NOUN
bjp-19567	45	10	plate	plate	NOUN
bjp-19567	45	11	at	at	ADP
bjp-19567	45	12	cell	cell	NOUN
bjp-19567	45	13	density	density	NOUN
bjp-19567	45	14	of	of	ADP
bjp-19567	45	15	2	2	NUM
bjp-19567	45	16	x	x	SYM
bjp-19567	45	17	104	104	NUM
bjp-19567	45	18	cells/	cells/	NOUN
bjp-19567	45	19	well	well	ADV
bjp-19567	45	20	and	and	CCONJ
bjp-19567	45	21	further	far	ADV
bjp-19567	45	22	incubated	incubate	VERB
bjp-19567	45	23	at	at	ADP
bjp-19567	45	24	37	37	NUM
bjp-19567	45	25	°	°	NOUN
bjp-19567	45	26	c	c	NOUN
bjp-19567	45	27	.	.	PUNCT
bjp-19567	46	1	after	after	ADP
bjp-19567	46	2	24	24	NUM
bjp-19567	46	3	hours	hour	NOUN
bjp-19567	46	4	,	,	PUNCT
bjp-19567	46	5	cells	cell	NOUN
bjp-19567	46	6	were	be	AUX
bjp-19567	46	7	treated	treat	VERB
bjp-19567	46	8	with	with	ADP
bjp-19567	46	9	various	various	ADJ
bjp-19567	46	10	doses	dose	NOUN
bjp-19567	46	11	(	(	PUNCT
bjp-19567	46	12	0.5	0.5	NUM
bjp-19567	46	13	,	,	PUNCT
bjp-19567	46	14	1	1	NUM
bjp-19567	46	15	,	,	PUNCT
bjp-19567	46	16	2.5	2.5	NUM
bjp-19567	46	17	,	,	PUNCT
bjp-19567	46	18	5	5	NUM
bjp-19567	46	19	and	and	CCONJ
bjp-19567	46	20	10	10	NUM
bjp-19567	46	21	µm	µm	NOUN
bjp-19567	46	22	)	)	PUNCT
bjp-19567	46	23	of	of	ADP
bjp-19567	46	24	nobiletin	nobiletin	NOUN
bjp-19567	46	25	for	for	ADP
bjp-19567	46	26	0	0	NUM
bjp-19567	46	27	,	,	PUNCT
bjp-19567	46	28	24	24	NUM
bjp-19567	46	29	,	,	PUNCT
bjp-19567	46	30	48	48	NUM
bjp-19567	46	31	and	and	CCONJ
bjp-19567	46	32	72	72	NUM
bjp-19567	46	33	hours	hour	NOUN
bjp-19567	46	34	.	.	PUNCT
bjp-19567	47	1	from	from	ADP
bjp-19567	47	2	each	each	PRON
bjp-19567	47	3	well	well	NOUN
bjp-19567	47	4	,	,	PUNCT
bjp-19567	47	5	cell	cell	NOUN
bjp-19567	47	6	culture	culture	NOUN
bjp-19567	47	7	medium	medium	NOUN
bjp-19567	47	8	was	be	AUX
bjp-19567	47	9	collected	collect	VERB
bjp-19567	47	10	and	and	CCONJ
bjp-19567	47	11	mixed	mix	VERB
bjp-19567	47	12	with	with	ADP
bjp-19567	47	13	pbs	pbs	PROPN
bjp-19567	47	14	and	and	CCONJ
bjp-19567	47	15	ldh	ldh	VERB
bjp-19567	47	16	reagent	reagent	NOUN
bjp-19567	47	17	in	in	ADP
bjp-19567	47	18	ratio	ratio	NOUN
bjp-19567	47	19	of	of	ADP
bjp-19567	47	20	1:4:5	1:4:5	NUM
bjp-19567	47	21	and	and	CCONJ
bjp-19567	47	22	kept	keep	VERB
bjp-19567	47	23	in	in	ADP
bjp-19567	47	24	dark	dark	NOUN
bjp-19567	47	25	for	for	ADP
bjp-19567	47	26	1	1	NUM
bjp-19567	47	27	hour	hour	NOUN
bjp-19567	47	28	at	at	ADP
bjp-19567	47	29	25	25	NUM
bjp-19567	47	30	°	°	NOUN
bjp-19567	47	31	c	c	NOUN
bjp-19567	47	32	.	.	PUNCT
bjp-19567	48	1	following	follow	VERB
bjp-19567	48	2	the	the	DET
bjp-19567	48	3	addition	addition	NOUN
bjp-19567	48	4	of	of	ADP
bjp-19567	48	5	50	50	NUM
bjp-19567	48	6	μl	μl	ADP
bjp-19567	48	7	of	of	ADP
bjp-19567	48	8	stop	stop	NOUN
bjp-19567	48	9	solution	solution	NOUN
bjp-19567	48	10	,	,	PUNCT
bjp-19567	48	11	absorbance	absorbance	NOUN
bjp-19567	48	12	was	be	AUX
bjp-19567	48	13	measured	measure	VERB
bjp-19567	48	14	at	at	ADP
bjp-19567	48	15	490	490	NUM
bjp-19567	48	16	nm	nm	NOUN
bjp-19567	48	17	.	.	PUNCT
bjp-19567	49	1	flow	flow	VERB
bjp-19567	49	2	cytometric	cytometric	ADJ
bjp-19567	49	3	study	study	NOUN
bjp-19567	49	4	for	for	ADP
bjp-19567	49	5	apoptosis	apoptosis	NOUN
bjp-19567	49	6	evaluation	evaluation	NOUN
bjp-19567	49	7	after	after	SCONJ
bjp-19567	49	8	saos-2	saos-2	NUM
bjp-19567	49	9	cells	cell	NOUN
bjp-19567	49	10	were	be	AUX
bjp-19567	49	11	treated	treat	VERB
bjp-19567	49	12	with	with	ADP
bjp-19567	49	13	nobiletin	nobiletin	NOUN
bjp-19567	49	14	at	at	ADP
bjp-19567	49	15	0.5	0.5	NUM
bjp-19567	49	16	,	,	PUNCT
bjp-19567	49	17	1	1	NUM
bjp-19567	49	18	,	,	PUNCT
bjp-19567	49	19	2.5	2.5	NUM
bjp-19567	49	20	,	,	PUNCT
bjp-19567	49	21	5	5	NUM
bjp-19567	49	22	and	and	CCONJ
bjp-19567	49	23	10	10	NUM
bjp-19567	49	24	µm	µm	ADP
bjp-19567	49	25	doses	dose	NOUN
bjp-19567	49	26	for	for	ADP
bjp-19567	49	27	24	24	NUM
bjp-19567	49	28	hours	hour	NOUN
bjp-19567	49	29	,	,	PUNCT
bjp-19567	49	30	cells	cell	NOUN
bjp-19567	49	31	were	be	AUX
bjp-19567	49	32	harvested	harvest	VERB
bjp-19567	49	33	and	and	CCONJ
bjp-19567	49	34	collected	collect	VERB
bjp-19567	49	35	as	as	ADP
bjp-19567	49	36	pellet	pellet	NOUN
bjp-19567	49	37	(	(	PUNCT
bjp-19567	49	38	1,000	1,000	NUM
bjp-19567	49	39	rpm	rpm	NOUN
bjp-19567	49	40	for	for	ADP
bjp-19567	49	41	5	5	NUM
bjp-19567	49	42	min	min	NOUN
bjp-19567	49	43	)	)	PUNCT
bjp-19567	49	44	.	.	PUNCT
bjp-19567	50	1	subsequently	subsequently	ADV
bjp-19567	50	2	,	,	PUNCT
bjp-19567	50	3	cells	cell	NOUN
bjp-19567	50	4	were	be	AUX
bjp-19567	50	5	fixed	fix	VERB
bjp-19567	50	6	with	with	ADP
bjp-19567	50	7	70	70	NUM
bjp-19567	50	8	%	%	NOUN
bjp-19567	50	9	ice	ice	NOUN
bjp-19567	50	10	cold	cold	ADJ
bjp-19567	50	11	ethanol	ethanol	NOUN
bjp-19567	50	12	and	and	CCONJ
bjp-19567	50	13	washed	wash	VERB
bjp-19567	50	14	twice	twice	ADV
bjp-19567	50	15	with	with	ADP
bjp-19567	50	16	pbs	pbs	PROPN
bjp-19567	50	17	.	.	PUNCT
bjp-19567	51	1	cells	cell	NOUN
bjp-19567	51	2	were	be	AUX
bjp-19567	51	3	further	far	ADV
bjp-19567	51	4	treated	treat	VERB
bjp-19567	51	5	with	with	ADP
bjp-19567	51	6	triton	triton	PROPN
bjp-19567	51	7	x-100	x-100	PROPN
bjp-19567	52	1	(	(	PUNCT
bjp-19567	52	2	1	1	NUM
bjp-19567	52	3	%	%	NOUN
bjp-19567	52	4	v	v	ADP
bjp-19567	52	5	/	/	SYM
bjp-19567	52	6	v	v	NOUN
bjp-19567	52	7	)	)	PUNCT
bjp-19567	53	1	and	and	CCONJ
bjp-19567	53	2	incubated	incubate	VERB
bjp-19567	53	3	at	at	ADP
bjp-19567	53	4	37	37	NUM
bjp-19567	53	5	°	°	ADP
bjp-19567	53	6	c	c	NOUN
bjp-19567	53	7	for	for	ADP
bjp-19567	53	8	10	10	NUM
bjp-19567	53	9	min	min	NOUN
bjp-19567	53	10	.	.	PROPN
bjp-19567	53	11	50	50	NUM
bjp-19567	53	12	µg	µg	NOUN
bjp-19567	53	13	/	/	SYM
bjp-19567	53	14	ml	ml	NOUN
bjp-19567	53	15	of	of	ADP
bjp-19567	53	16	propidium	propidium	NOUN
bjp-19567	53	17	iodide	iodide	NOUN
bjp-19567	53	18	solution	solution	NOUN
bjp-19567	53	19	was	be	AUX
bjp-19567	53	20	then	then	ADV
bjp-19567	53	21	added	add	VERB
bjp-19567	53	22	to	to	ADP
bjp-19567	53	23	the	the	DET
bjp-19567	53	24	cells	cell	NOUN
bjp-19567	53	25	at	at	ADP
bjp-19567	53	26	4	4	NUM
bjp-19567	53	27	°	°	ADP
bjp-19567	53	28	c	c	NOUN
bjp-19567	53	29	for	for	ADP
bjp-19567	53	30	15	15	NUM
bjp-19567	53	31	min	min	NOUN
bjp-19567	53	32	in	in	ADP
bjp-19567	53	33	the	the	DET
bjp-19567	53	34	darkto	darkto	ADJ
bjp-19567	53	35	stain	stain	NOUN
bjp-19567	53	36	the	the	DET
bjp-19567	53	37	cellular	cellular	ADJ
bjp-19567	53	38	dna	dna	NOUN
bjp-19567	53	39	.	.	PUNCT
bjp-19567	54	1	the	the	DET
bjp-19567	54	2	distribution	distribution	NOUN
bjp-19567	54	3	of	of	ADP
bjp-19567	54	4	cells	cell	NOUN
bjp-19567	54	5	in	in	ADP
bjp-19567	54	6	the	the	DET
bjp-19567	54	7	phases	phase	NOUN
bjp-19567	54	8	of	of	ADP
bjp-19567	54	9	cell	cell	NOUN
bjp-19567	54	10	cycle	cycle	NOUN
bjp-19567	54	11	and	and	CCONJ
bjp-19567	54	12	apoptotic	apoptotic	ADJ
bjp-19567	54	13	rate	rate	NOUN
bjp-19567	54	14	was	be	AUX
bjp-19567	54	15	then	then	ADV
bjp-19567	54	16	determined	determine	VERB
bjp-19567	54	17	using	use	VERB
bjp-19567	54	18	facscan	facscan	PROPN
bjp-19567	54	19	f	f	PROPN
bjp-19567	54	20	low	low	PROPN
bjp-19567	54	21	cyto	cyto	PROPN
bjp-19567	54	22	meter	meter	NOUN
bjp-19567	54	23	(	(	PUNCT
bjp-19567	54	24	bd	bd	PROPN
bjp-19567	54	25	biosciences	bioscience	NOUN
bjp-19567	54	26	,	,	PUNCT
bjp-19567	54	27	san	san	PROPN
bjp-19567	54	28	jose	jose	PROPN
bjp-19567	54	29	,	,	PUNCT
bjp-19567	54	30	ca	ca	PROPN
bjp-19567	54	31	,	,	PUNCT
bjp-19567	54	32	usa	usa	PROPN
bjp-19567	54	33	)	)	PUNCT
bjp-19567	54	34	western	western	ADJ
bjp-19567	54	35	blot	blot	NOUN
bjp-19567	54	36	analysis	analysis	NOUN
bjp-19567	54	37	total	total	ADJ
bjp-19567	54	38	cell	cell	NOUN
bjp-19567	54	39	lysate	lysate	NOUN
bjp-19567	54	40	was	be	AUX
bjp-19567	54	41	collected	collect	VERB
bjp-19567	54	42	fromsaos-2	fromsaos-2	NUM
bjp-19567	54	43	cells	cell	NOUN
bjp-19567	54	44	treated	treat	VERB
bjp-19567	54	45	with	with	ADP
bjp-19567	54	46	nobiletin	nobiletin	NOUN
bjp-19567	54	47	for	for	ADP
bjp-19567	54	48	24	24	NUM
bjp-19567	54	49	hours	hour	NOUN
bjp-19567	54	50	in	in	ADP
bjp-19567	54	51	ice	ice	NOUN
bjp-19567	54	52	cold	cold	ADJ
bjp-19567	54	53	ripa	ripa	NOUN
bjp-19567	54	54	buffer	buffer	NOUN
bjp-19567	54	55	containing	contain	VERB
bjp-19567	54	56	protease	protease	NOUN
bjp-19567	54	57	inhibitor	inhibitor	NOUN
bjp-19567	54	58	cock	cock	NOUN
bjp-19567	54	59	-	-	PUNCT
bjp-19567	54	60	tail	tail	NOUN
bjp-19567	54	61	(	(	PUNCT
bjp-19567	54	62	roche	roche	NOUN
bjp-19567	54	63	)	)	PUNCT
bjp-19567	54	64	.	.	PUNCT
bjp-19567	55	1	thereafter	thereafter	ADV
bjp-19567	55	2	,	,	PUNCT
bjp-19567	55	3	samples	sample	NOUN
bjp-19567	55	4	were	be	AUX
bjp-19567	55	5	vortexed	vortexe	VERB
bjp-19567	55	6	and	and	CCONJ
bjp-19567	55	7	centrifuged	centrifuge	VERB
bjp-19567	55	8	at	at	ADP
bjp-19567	55	9	12,000	12,000	NUM
bjp-19567	55	10	rpm	rpm	NOUN
bjp-19567	55	11	for	for	ADP
bjp-19567	55	12	30	30	NUM
bjp-19567	55	13	min	min	NOUN
bjp-19567	55	14	to	to	PART
bjp-19567	55	15	collect	collect	VERB
bjp-19567	55	16	the	the	DET
bjp-19567	55	17	supernatant	supernatant	NOUN
bjp-19567	55	18	.	.	PUNCT
bjp-19567	56	1	total	total	ADJ
bjp-19567	56	2	protein	protein	NOUN
bjp-19567	56	3	amount	amount	NOUN
bjp-19567	56	4	was	be	AUX
bjp-19567	56	5	determined	determine	VERB
bjp-19567	56	6	using	use	VERB
bjp-19567	56	7	protein	protein	NOUN
bjp-19567	56	8	assay	assay	ADJ
bjp-19567	56	9	reagent	reagent	NOUN
bjp-19567	56	10	(	(	PUNCT
bjp-19567	56	11	bio	bio	NOUN
bjp-19567	56	12	-	-	NOUN
bjp-19567	56	13	rad	rad	NOUN
bjp-19567	56	14	)	)	PUNCT
bjp-19567	56	15	to	to	PART
bjp-19567	56	16	normalize	normalize	VERB
bjp-19567	56	17	the	the	DET
bjp-19567	56	18	protein	protein	NOUN
bjp-19567	56	19	content	content	NOUN
bjp-19567	56	20	.	.	PUNCT
bjp-19567	57	1	equal	equal	ADJ
bjp-19567	57	2	amount	amount	NOUN
bjp-19567	57	3	of	of	ADP
bjp-19567	57	4	proteins	protein	NOUN
bjp-19567	57	5	were	be	AUX
bjp-19567	57	6	separated	separate	VERB
bjp-19567	57	7	on	on	ADP
bjp-19567	57	8	10	10	NUM
bjp-19567	57	9	-	-	SYM
bjp-19567	57	10	12	12	NUM
bjp-19567	57	11	%	%	NOUN
bjp-19567	57	12	sodium	sodium	NOUN
bjp-19567	57	13	deodecyl	deodecyl	ADP
bjp-19567	57	14	sulfate	sulfate	NOUN
bjp-19567	57	15	-	-	PUNCT
bjp-19567	57	16	polyacrylamide	polyacrylamide	NOUN
bjp-19567	57	17	gel	gel	NOUN
bjp-19567	57	18	electrophoresis	electrophoresis	NOUN
bjp-19567	57	19	and	and	CCONJ
bjp-19567	57	20	then	then	ADV
bjp-19567	57	21	electrophoretically	electrophoretically	ADV
bjp-19567	57	22	transferred	transfer	VERB
bjp-19567	57	23	to	to	ADP
bjp-19567	57	24	nitrocellulose	nitrocellulose	NOUN
bjp-19567	57	25	membrane	membrane	NOUN
bjp-19567	57	26	.	.	PUNCT
bjp-19567	58	1	tween	tween	NOUN
bjp-19567	58	2	20	20	NUM
bjp-19567	58	3	-	-	PUNCT
bjp-19567	58	4	tris	tris	NOUN
bjp-19567	58	5	buffered	buffer	VERB
bjp-19567	58	6	saline	saline	NOUN
bjp-19567	58	7	(	(	PUNCT
bjp-19567	58	8	tbst	tbst	NOUN
bjp-19567	58	9	)	)	PUNCT
bjp-19567	58	10	including	include	VERB
bjp-19567	58	11	nonfat	nonfat	NOUN
bjp-19567	58	12	dry	dry	ADJ
bjp-19567	58	13	milk	milk	NOUN
bjp-19567	58	14	(	(	PUNCT
bjp-19567	58	15	5	5	NUM
bjp-19567	58	16	%	%	NOUN
bjp-19567	58	17	)	)	PUNCT
bjp-19567	58	18	was	be	AUX
bjp-19567	58	19	spread	spread	VERB
bjp-19567	58	20	on	on	ADP
bjp-19567	58	21	the	the	DET
bjp-19567	58	22	membrane	membrane	NOUN
bjp-19567	58	23	at	at	ADP
bjp-19567	58	24	room	room	NOUN
bjp-19567	58	25	temperature	temperature	NOUN
bjp-19567	58	26	for	for	ADP
bjp-19567	58	27	1	1	NUM
bjp-19567	58	28	hour	hour	NOUN
bjp-19567	58	29	to	to	PART
bjp-19567	58	30	block	block	VERB
bjp-19567	58	31	non	non	ADJ
bjp-19567	58	32	-	-	ADJ
bjp-19567	58	33	specific	specific	ADJ
bjp-19567	58	34	sites	site	NOUN
bjp-19567	58	35	and	and	CCONJ
bjp-19567	58	36	then	then	ADV
bjp-19567	58	37	the	the	DET
bjp-19567	58	38	membrane	membrane	NOUN
bjp-19567	58	39	was	be	AUX
bjp-19567	58	40	incubated	incubate	VERB
bjp-19567	58	41	overnight	overnight	ADV
bjp-19567	58	42	with	with	ADP
bjp-19567	58	43	primary	primary	ADJ
bjp-19567	58	44	antibodies	antibody	NOUN
bjp-19567	58	45	(	(	PUNCT
bjp-19567	58	46	pakt	pakt	NOUN
bjp-19567	58	47	,	,	PUNCT
bjp-19567	58	48	perk	perk	NOUN
bjp-19567	58	49	,	,	PUNCT
bjp-19567	58	50	erk	erk	PROPN
bjp-19567	58	51	,	,	PUNCT
bjp-19567	58	52	akt	akt	PROPN
bjp-19567	58	53	and	and	CCONJ
bjp-19567	58	54	-actin	-actin	PROPN
bjp-19567	58	55	)	)	PUNCT
bjp-19567	58	56	at	at	ADP
bjp-19567	58	57	4	4	NUM
bjp-19567	58	58	°	°	NOUN
bjp-19567	58	59	c	c	NOUN
bjp-19567	58	60	.	.	PUNCT
bjp-19567	59	1	the	the	DET
bjp-19567	59	2	membrane	membrane	NOUN
bjp-19567	59	3	was	be	AUX
bjp-19567	59	4	washed	wash	VERB
bjp-19567	59	5	again	again	ADV
bjp-19567	59	6	with	with	ADP
bjp-19567	59	7	tbst	tbst	PROPN
bjp-19567	59	8	three	three	NUM
bjp-19567	59	9	times	time	NOUN
bjp-19567	59	10	and	and	CCONJ
bjp-19567	59	11	then	then	ADV
bjp-19567	59	12	incubated	incubate	VERB
bjp-19567	59	13	with	with	ADP
bjp-19567	59	14	appropriate	appropriate	ADJ
bjp-19567	59	15	horseradish	horseradish	ADJ
bjp-19567	59	16	peroxidase	peroxidase	NOUN
bjp-19567	59	17	(	(	PUNCT
bjp-19567	59	18	hrp	hrp	PROPN
bjp-19567	59	19	)	)	PUNCT
bjp-19567	59	20	conjugated	conjugate	VERB
bjp-19567	59	21	rabbit	rabbit	NOUN
bjp-19567	59	22	anti	anti	ADJ
bjp-19567	59	23	-	-	ADJ
bjp-19567	59	24	mouse	mouse	ADJ
bjp-19567	59	25	secondary	secondary	ADJ
bjp-19567	59	26	antibody	antibody	NOUN
bjp-19567	59	27	(	(	PUNCT
bjp-19567	59	28	santa	santa	PROPN
bjp-19567	59	29	cruz	cruz	PROPN
bjp-19567	59	30	biotech	biotech	PROPN
bjp-19567	59	31	,	,	PUNCT
bjp-19567	59	32	ca	ca	PROPN
bjp-19567	59	33	,	,	PUNCT
bjp-19567	59	34	usa	usa	PROPN
bjp-19567	59	35	)	)	PUNCT
bjp-19567	59	36	for	for	ADP
bjp-19567	59	37	1	1	NUM
bjp-19567	59	38	hour	hour	NOUN
bjp-19567	59	39	at	at	ADP
bjp-19567	59	40	room	room	NOUN
bjp-19567	59	41	temperature	temperature	NOUN
bjp-19567	59	42	.	.	PUNCT
bjp-19567	60	1	again	again	ADV
bjp-19567	60	2	after	after	ADP
bjp-19567	60	3	three	three	NUM
bjp-19567	60	4	times	time	NOUN
bjp-19567	60	5	washing	wash	VERB
bjp-19567	60	6	the	the	DET
bjp-19567	60	7	membrane	membrane	NOUN
bjp-19567	60	8	with	with	ADP
bjp-19567	60	9	tbst	tbst	NOUN
bjp-19567	60	10	,	,	PUNCT
bjp-19567	60	11	bands	band	NOUN
bjp-19567	60	12	were	be	AUX
bjp-19567	60	13	visualized	visualize	VERB
bjp-19567	60	14	by	by	ADP
bjp-19567	60	15	enhances	enhance	NOUN
bjp-19567	60	16	chemiluminescence	chemiluminescence	NOUN
bjp-19567	60	17	detection	detection	NOUN
bjp-19567	60	18	system	system	NOUN
bjp-19567	60	19	(	(	PUNCT
bjp-19567	60	20	fujfilm	fujfilm	NOUN
bjp-19567	60	21	las3000	las3000	X
bjp-19567	60	22	mini	mini	PROPN
bjp-19567	60	23	,	,	PUNCT
bjp-19567	60	24	tokyo	tokyo	PROPN
bjp-19567	60	25	,	,	PUNCT
bjp-19567	60	26	japan	japan	PROPN
bjp-19567	60	27	)	)	PUNCT
bjp-19567	60	28	.	.	PUNCT
bjp-19567	61	1	caspase-3	caspase-3	NUM
bjp-19567	61	2	and	and	CCONJ
bjp-19567	61	3	-9	-9	ADV
bjp-19567	61	4	activity	activity	NOUN
bjp-19567	61	5	assay	assay	VERB
bjp-19567	61	6	to	to	PART
bjp-19567	61	7	confirm	confirm	VERB
bjp-19567	61	8	the	the	DET
bjp-19567	61	9	apoptotic	apoptotic	ADJ
bjp-19567	61	10	activity	activity	NOUN
bjp-19567	61	11	,	,	PUNCT
bjp-19567	61	12	caspase-3	caspase-3	NUM
bjp-19567	61	13	and	and	CCONJ
bjp-19567	61	14	-9	-9	PROPN
bjp-19567	61	15	were	be	AUX
bjp-19567	61	16	determined	determine	VERB
bjp-19567	61	17	using	use	VERB
bjp-19567	61	18	caspase-3	caspase-3	NUM
bjp-19567	61	19	and	and	CCONJ
bjp-19567	61	20	-9	-9	ADV
bjp-19567	61	21	colorimetric	colorimetric	ADJ
bjp-19567	61	22	assay	assay	PROPN
bjp-19567	61	23	bangladesh	bangladesh	PROPN
bjp-19567	61	24	j	j	PROPN
bjp-19567	61	25	pharmacol	pharmacol	PROPN
bjp-19567	61	26	2014	2014	NUM
bjp-19567	61	27	;	;	PUNCT
bjp-19567	61	28	9	9	NUM
bjp-19567	61	29	:	:	SYM
bjp-19567	61	30	406	406	NUM
bjp-19567	61	31	-	-	SYM
bjp-19567	61	32	412	412	NUM
bjp-19567	61	33	407	407	NUM
bjp-19567	61	34	kit	kit	NOUN
bjp-19567	61	35	,	,	PUNCT
bjp-19567	61	36	according	accord	VERB
bjp-19567	61	37	to	to	ADP
bjp-19567	61	38	manufacturer	manufacturer	PROPN
bjp-19567	61	39	’s	’s	PART
bjp-19567	61	40	protocol	protocol	NOUN
bjp-19567	61	41	.	.	PUNCT
bjp-19567	62	1	after	after	SCONJ
bjp-19567	62	2	the	the	DET
bjp-19567	62	3	treat	treat	ADJ
bjp-19567	62	4	-ment	-ment	NOUN
bjp-19567	62	5	of	of	ADP
bjp-19567	62	6	saos-2	saos-2	NUM
bjp-19567	62	7	cells	cell	NOUN
bjp-19567	62	8	with	with	ADP
bjp-19567	62	9	nobiletin	nobiletin	NOUN
bjp-19567	62	10	,	,	PUNCT
bjp-19567	62	11	total	total	ADJ
bjp-19567	62	12	cells	cell	NOUN
bjp-19567	62	13	were	be	AUX
bjp-19567	62	14	collected	collect	VERB
bjp-19567	62	15	as	as	ADP
bjp-19567	62	16	pellet	pellet	NOUN
bjp-19567	62	17	by	by	ADP
bjp-19567	62	18	centrifuging	centrifuge	VERB
bjp-19567	62	19	at	at	ADP
bjp-19567	62	20	12,000	12,000	NUM
bjp-19567	62	21	x	x	SYM
bjp-19567	62	22	g	g	NOUN
bjp-19567	62	23	for	for	ADP
bjp-19567	62	24	10	10	NUM
bjp-19567	62	25	min	min	NOUN
bjp-19567	62	26	.	.	PROPN
bjp-19567	62	27	pellet	pellet	NOUN
bjp-19567	62	28	was	be	AUX
bjp-19567	62	29	then	then	ADV
bjp-19567	62	30	resuspended	resuspend	VERB
bjp-19567	62	31	in	in	ADP
bjp-19567	62	32	50	50	NUM
bjp-19567	62	33	µl	µl	NOUN
bjp-19567	62	34	of	of	ADP
bjp-19567	62	35	ice	ice	NOUN
bjp-19567	62	36	cold	cold	ADJ
bjp-19567	62	37	lysis	lysis	NOUN
bjp-19567	62	38	buffer	buffer	NOUN
bjp-19567	62	39	for	for	ADP
bjp-19567	62	40	10	10	NUM
bjp-19567	62	41	min	min	NOUN
bjp-19567	62	42	at	at	ADP
bjp-19567	62	43	4	4	NUM
bjp-19567	62	44	°	°	ADP
bjp-19567	62	45	c	c	NOUN
bjp-19567	62	46	and	and	CCONJ
bjp-19567	62	47	centrifuged	centrifuge	VERB
bjp-19567	62	48	again	again	ADV
bjp-19567	62	49	at	at	ADP
bjp-19567	62	50	10,000	10,000	NUM
bjp-19567	62	51	x	x	SYM
bjp-19567	62	52	g	g	NOUN
bjp-19567	62	53	for	for	ADP
bjp-19567	62	54	1	1	NUM
bjp-19567	62	55	min	min	NOUN
bjp-19567	62	56	to	to	PART
bjp-19567	62	57	collect	collect	VERB
bjp-19567	62	58	supernatant	supernatant	NOUN
bjp-19567	62	59	.	.	PUNCT
bjp-19567	63	1	after	after	ADP
bjp-19567	63	2	the	the	DET
bjp-19567	63	3	quantification	quantification	NOUN
bjp-19567	63	4	of	of	ADP
bjp-19567	63	5	total	total	ADJ
bjp-19567	63	6	protein	protein	NOUN
bjp-19567	63	7	in	in	ADP
bjp-19567	63	8	the	the	DET
bjp-19567	63	9	supernatant	supernatant	NOUN
bjp-19567	63	10	,	,	PUNCT
bjp-19567	63	11	respective	respective	ADJ
bjp-19567	63	12	substrates	substrate	NOUN
bjp-19567	63	13	were	be	AUX
bjp-19567	63	14	added	add	VERB
bjp-19567	63	15	to	to	ADP
bjp-19567	63	16	equal	equal	ADJ
bjp-19567	63	17	amount	amount	NOUN
bjp-19567	63	18	of	of	ADP
bjp-19567	63	19	proteins	protein	NOUN
bjp-19567	63	20	and	and	CCONJ
bjp-19567	63	21	incubated	incubate	VERB
bjp-19567	63	22	at	at	ADP
bjp-19567	63	23	37	37	NUM
bjp-19567	63	24	°	°	ADP
bjp-19567	63	25	c	c	NOUN
bjp-19567	63	26	for	for	ADP
bjp-19567	63	27	30	30	NUM
bjp-19567	63	28	min	min	NOUN
bjp-19567	63	29	.	.	PROPN
bjp-19567	63	30	activity	activity	NOUN
bjp-19567	63	31	was	be	AUX
bjp-19567	63	32	determined	determine	VERB
bjp-19567	63	33	by	by	ADP
bjp-19567	63	34	reading	read	VERB
bjp-19567	63	35	the	the	DET
bjp-19567	63	36	samples	sample	NOUN
bjp-19567	63	37	at	at	ADP
bjp-19567	63	38	400	400	NUM
bjp-19567	63	39	nm	nm	NOUN
bjp-19567	63	40	in	in	ADP
bjp-19567	63	41	a	a	DET
bjp-19567	63	42	microtiter	microtiter	ADJ
bjp-19567	63	43	plate	plate	NOUN
bjp-19567	63	44	reader	reader	NOUN
bjp-19567	63	45	.	.	PUNCT
bjp-19567	64	1	over	over	ADP
bjp-19567	64	2	expression	expression	NOUN
bjp-19567	64	3	of	of	ADP
bjp-19567	64	4	akt	akt	PROPN
bjp-19567	64	5	allele	allele	NOUN
bjp-19567	64	6	saos-2	saos-2	NUM
bjp-19567	64	7	cells	cell	NOUN
bjp-19567	64	8	were	be	AUX
bjp-19567	64	9	plated	plate	VERB
bjp-19567	64	10	at	at	ADP
bjp-19567	64	11	3.5	3.5	NUM
bjp-19567	64	12	x	x	SYM
bjp-19567	64	13	104	104	NUM
bjp-19567	64	14	cells	cell	NOUN
bjp-19567	64	15	/	/	SYM
bjp-19567	64	16	well	well	ADV
bjp-19567	64	17	in	in	ADP
bjp-19567	64	18	a	a	DET
bjp-19567	64	19	48well	48well	X
bjp-19567	64	20	dish	dish	NOUN
bjp-19567	64	21	and	and	CCONJ
bjp-19567	64	22	transfected	transfecte	VERB
bjp-19567	64	23	with	with	ADP
bjp-19567	64	24	0.75	0.75	NUM
bjp-19567	64	25	μg	μg	PROPN
bjp-19567	64	26	of	of	ADP
bjp-19567	64	27	myraktdeltaph	myraktdeltaph	PROPN
bjp-19567	64	28	plasmid	plasmid	ADJ
bjp-19567	64	29	dna	dna	PROPN
bjp-19567	64	30	(	(	PUNCT
bjp-19567	64	31	addgene	addgene	PROPN
bjp-19567	64	32	,	,	PUNCT
bjp-19567	64	33	cambridge	cambridge	PROPN
bjp-19567	64	34	,	,	PUNCT
bjp-19567	64	35	ma:10841	ma:10841	PROPN
bjp-19567	64	36	)	)	PUNCT
bjp-19567	64	37	,	,	PUNCT
bjp-19567	64	38	encoding	encode	VERB
bjp-19567	64	39	myr	myr	PROPN
bjp-19567	64	40	-	-	PUNCT
bjp-19567	64	41	akt	akt	PROPN
bjp-19567	64	42	,	,	PUNCT
bjp-19567	64	43	or	or	CCONJ
bjp-19567	64	44	empty	empty	ADJ
bjp-19567	64	45	plasmid	plasmid	ADJ
bjp-19567	64	46	pece	pece	NOUN
bjp-19567	64	47	(	(	PUNCT
bjp-19567	64	48	addgene:26453),as	addgene:26453),as	INTJ
bjp-19567	64	49	control	control	NOUN
bjp-19567	64	50	,	,	PUNCT
bjp-19567	64	51	with	with	ADP
bjp-19567	64	52	fugene	fugene	ADJ
bjp-19567	64	53	hd	hd	PROPN
bjp-19567	64	54	(	(	PUNCT
bjp-19567	64	55	promega	promega	PROPN
bjp-19567	64	56	,	,	PUNCT
bjp-19567	64	57	sunnyvale	sunnyvale	PROPN
bjp-19567	64	58	,	,	PUNCT
bjp-19567	64	59	ca)transfection	ca)transfection	NOUN
bjp-19567	64	60	reagent	reagent	NOUN
bjp-19567	64	61	according	accord	VERB
bjp-19567	64	62	to	to	ADP
bjp-19567	64	63	the	the	DET
bjp-19567	64	64	manufacturer	manufacturer	NOUN
bjp-19567	64	65	’s	’s	PART
bjp-19567	64	66	protocol	protocol	NOUN
bjp-19567	64	67	.	.	PUNCT
bjp-19567	65	1	after	after	ADP
bjp-19567	65	2	8	8	NUM
bjp-19567	65	3	hours	hour	NOUN
bjp-19567	65	4	of	of	ADP
bjp-19567	65	5	transfection	transfection	NOUN
bjp-19567	65	6	,	,	PUNCT
bjp-19567	65	7	cells	cell	NOUN
bjp-19567	65	8	were	be	AUX
bjp-19567	65	9	treated	treat	VERB
bjp-19567	65	10	with	with	ADP
bjp-19567	65	11	nobiletin	nobiletin	NOUN
bjp-19567	65	12	for	for	ADP
bjp-19567	65	13	24	24	NUM
bjp-19567	65	14	hours	hour	NOUN
bjp-19567	65	15	.	.	PUNCT
bjp-19567	66	1	mtt	mtt	PROPN
bjp-19567	66	2	assay	assay	PROPN
bjp-19567	66	3	was	be	AUX
bjp-19567	66	4	performed	perform	VERB
bjp-19567	66	5	to	to	PART
bjp-19567	66	6	assess	assess	VERB
bjp-19567	66	7	the	the	DET
bjp-19567	66	8	cell	cell	NOUN
bjp-19567	66	9	viability	viability	NOUN
bjp-19567	66	10	of	of	ADP
bjp-19567	66	11	treated	treat	VERB
bjp-19567	66	12	cells	cell	NOUN
bjp-19567	66	13	as	as	SCONJ
bjp-19567	66	14	described	describe	VERB
bjp-19567	66	15	above	above	ADV
bjp-19567	66	16	.	.	PUNCT
bjp-19567	67	1	inhibition	inhibition	NOUN
bjp-19567	67	2	of	of	ADP
bjp-19567	67	3	erk	erk	NOUN
bjp-19567	67	4	signaling	signal	VERB
bjp-19567	67	5	pathway	pathway	NOUN
bjp-19567	67	6	saos-2	saos-2	NUM
bjp-19567	67	7	cells	cell	NOUN
bjp-19567	67	8	plated	plate	VERB
bjp-19567	67	9	at	at	ADP
bjp-19567	67	10	a	a	DET
bjp-19567	67	11	density	density	NOUN
bjp-19567	67	12	of	of	ADP
bjp-19567	67	13	3.5	3.5	NUM
bjp-19567	67	14	x	x	SYM
bjp-19567	67	15	104	104	NUM
bjp-19567	67	16	cells	cell	NOUN
bjp-19567	67	17	/	/	SYM
bjp-19567	67	18	well	well	ADV
bjp-19567	67	19	in	in	ADP
bjp-19567	67	20	a	a	DET
bjp-19567	67	21	48	48	NUM
bjp-19567	67	22	-	-	PUNCT
bjp-19567	67	23	well	well	NOUN
bjp-19567	67	24	dish	dish	NOUN
bjp-19567	67	25	were	be	AUX
bjp-19567	67	26	treated	treat	VERB
bjp-19567	67	27	with	with	ADP
bjp-19567	67	28	nobiletin	nobiletin	NOUN
bjp-19567	67	29	,	,	PUNCT
bjp-19567	67	30	with	with	ADP
bjp-19567	67	31	or	or	CCONJ
bjp-19567	67	32	without	without	ADP
bjp-19567	67	33	pd98059	pd98059	NOUN
bjp-19567	67	34	(	(	PUNCT
bjp-19567	67	35	5	5	NUM
bjp-19567	67	36	μm	μm	NOUN
bjp-19567	67	37	)	)	PUNCT
bjp-19567	67	38	for	for	ADP
bjp-19567	67	39	24	24	NUM
bjp-19567	67	40	hours	hour	NOUN
bjp-19567	67	41	.	.	PUNCT
bjp-19567	68	1	cell	cell	NOUN
bjp-19567	68	2	viability	viability	NOUN
bjp-19567	68	3	of	of	ADP
bjp-19567	68	4	saos-2	saos-2	NUM
bjp-19567	68	5	cells	cell	NOUN
bjp-19567	68	6	was	be	AUX
bjp-19567	68	7	analyzed	analyze	VERB
bjp-19567	68	8	by	by	ADP
bjp-19567	68	9	mtt	mtt	NOUN
bjp-19567	68	10	assay	assay	NOUN
bjp-19567	68	11	.	.	PUNCT
bjp-19567	69	1	statistical	statistical	ADJ
bjp-19567	69	2	analysis	analysis	NOUN
bjp-19567	69	3	graphpad	graphpad	NOUN
bjp-19567	69	4	prism	prism	NOUN
bjp-19567	69	5	5.0	5.0	NUM
bjp-19567	69	6	(	(	PUNCT
bjp-19567	69	7	san	san	PROPN
bjp-19567	69	8	diego	diego	PROPN
bjp-19567	69	9	,	,	PUNCT
bjp-19567	69	10	ca	ca	PROPN
bjp-19567	69	11	)	)	PUNCT
bjp-19567	69	12	was	be	AUX
bjp-19567	69	13	utilized	utilize	VERB
bjp-19567	69	14	for	for	ADP
bjp-19567	69	15	evaluating	evaluate	VERB
bjp-19567	69	16	statistical	statistical	ADJ
bjp-19567	69	17	analysis	analysis	NOUN
bjp-19567	69	18	of	of	ADP
bjp-19567	69	19	obtained	obtain	VERB
bjp-19567	69	20	data	datum	NOUN
bjp-19567	69	21	by	by	ADP
bjp-19567	69	22	using	use	VERB
bjp-19567	69	23	two	two	NUM
bjp-19567	69	24	-	-	PUNCT
bjp-19567	69	25	tailed	tail	VERB
bjp-19567	69	26	student	student	NOUN
bjp-19567	69	27	t	t	NOUN
bjp-19567	69	28	-	-	PUNCT
bjp-19567	69	29	test	test	NOUN
bjp-19567	69	30	.	.	PUNCT
bjp-19567	70	1	statistical	statistical	ADJ
bjp-19567	70	2	significance	significance	NOUN
bjp-19567	70	3	was	be	AUX
bjp-19567	70	4	considered	consider	VERB
bjp-19567	70	5	at	at	ADP
bjp-19567	70	6	a	a	DET
bjp-19567	70	7	value	value	NOUN
bjp-19567	70	8	of	of	ADP
bjp-19567	70	9	p<0.05	p<0.05	NOUN
bjp-19567	70	10	.	.	PUNCT
bjp-19567	70	11	results	result	VERB
bjp-19567	70	12	the	the	DET
bjp-19567	70	13	anti	anti	ADJ
bjp-19567	70	14	-	-	ADJ
bjp-19567	70	15	proliferative	proliferative	ADJ
bjp-19567	70	16	effect	effect	NOUN
bjp-19567	70	17	of	of	ADP
bjp-19567	70	18	nobiletin	nobiletin	NOUN
bjp-19567	70	19	on	on	ADP
bjp-19567	70	20	osteosarcoma	osteosarcoma	ADJ
bjp-19567	70	21	cell	cell	NOUN
bjp-19567	70	22	line	line	NOUN
bjp-19567	70	23	was	be	AUX
bjp-19567	70	24	determined	determine	VERB
bjp-19567	70	25	following	follow	VERB
bjp-19567	70	26	24	24	NUM
bjp-19567	70	27	,	,	PUNCT
bjp-19567	70	28	48	48	NUM
bjp-19567	70	29	and	and	CCONJ
bjp-19567	70	30	72	72	NUM
bjp-19567	70	31	hours	hour	NOUN
bjp-19567	70	32	treatment	treatment	NOUN
bjp-19567	70	33	of	of	ADP
bjp-19567	70	34	saos-2	saos-2	NUM
bjp-19567	70	35	cells	cell	NOUN
bjp-19567	70	36	with	with	ADP
bjp-19567	70	37	nobiletin	nobiletin	NOUN
bjp-19567	70	38	at	at	ADP
bjp-19567	70	39	various	various	ADJ
bjp-19567	70	40	doses	dose	NOUN
bjp-19567	70	41	of	of	ADP
bjp-19567	70	42	0.5	0.5	NUM
bjp-19567	70	43	,	,	PUNCT
bjp-19567	70	44	1.0	1.0	NUM
bjp-19567	70	45	,	,	PUNCT
bjp-19567	70	46	2.5	2.5	NUM
bjp-19567	70	47	,	,	PUNCT
bjp-19567	70	48	5.0	5.0	NUM
bjp-19567	70	49	and	and	CCONJ
bjp-19567	70	50	10.0	10.0	NUM
bjp-19567	70	51	µm	µm	NOUN
bjp-19567	70	52	using	use	VERB
bjp-19567	70	53	mtt	mtt	NOUN
bjp-19567	70	54	assay	assay	NOUN
bjp-19567	70	55	.	.	PUNCT
bjp-19567	71	1	results	result	NOUN
bjp-19567	71	2	demonstrated	demonstrate	VERB
bjp-19567	71	3	growth	growth	NOUN
bjp-19567	71	4	inhibitory	inhibitory	ADJ
bjp-19567	71	5	effect	effect	NOUN
bjp-19567	71	6	of	of	ADP
bjp-19567	71	7	nobiletin	nobiletin	NOUN
bjp-19567	71	8	on	on	ADP
bjp-19567	71	9	saos-2	saos-2	NUM
bjp-19567	71	10	cells	cell	NOUN
bjp-19567	71	11	in	in	ADP
bjp-19567	71	12	a	a	DET
bjp-19567	71	13	dose	dose	NOUN
bjp-19567	71	14	-	-	PUNCT
bjp-19567	71	15	dependent	dependent	ADJ
bjp-19567	71	16	manner	manner	NOUN
bjp-19567	71	17	at	at	ADP
bjp-19567	71	18	all	all	DET
bjp-19567	71	19	the	the	DET
bjp-19567	71	20	time	time	NOUN
bjp-19567	71	21	points	point	NOUN
bjp-19567	71	22	(	(	PUNCT
bjp-19567	71	23	figure	figure	NOUN
bjp-19567	71	24	1a	1a	NOUN
bjp-19567	71	25	)	)	PUNCT
bjp-19567	71	26	.	.	PUNCT
bjp-19567	72	1	after	after	ADP
bjp-19567	72	2	24	24	NUM
bjp-19567	72	3	hours	hour	NOUN
bjp-19567	72	4	of	of	ADP
bjp-19567	72	5	treatment	treatment	NOUN
bjp-19567	72	6	,	,	PUNCT
bjp-19567	72	7	saos-2	saos-2	NUM
bjp-19567	72	8	cell	cell	NOUN
bjp-19567	72	9	viability	viability	NOUN
bjp-19567	72	10	was	be	AUX
bjp-19567	72	11	decreased	decrease	VERB
bjp-19567	72	12	to	to	ADP
bjp-19567	72	13	50	50	NUM
bjp-19567	72	14	and	and	CCONJ
bjp-19567	72	15	70	70	NUM
bjp-19567	72	16	%	%	NOUN
bjp-19567	72	17	of	of	ADP
bjp-19567	72	18	control	control	NOUN
bjp-19567	72	19	by	by	ADP
bjp-19567	72	20	nobiletin	nobiletin	NOUN
bjp-19567	72	21	at	at	ADP
bjp-19567	72	22	a	a	DET
bjp-19567	72	23	dose	dose	NOUN
bjp-19567	72	24	of	of	ADP
bjp-19567	72	25	5	5	NUM
bjp-19567	72	26	and	and	CCONJ
bjp-19567	72	27	10	10	NUM
bjp-19567	72	28	µm	µm	NOUN
bjp-19567	72	29	,	,	PUNCT
bjp-19567	72	30	respectively	respectively	ADV
bjp-19567	72	31	.	.	PUNCT
bjp-19567	73	1	even	even	ADV
bjp-19567	73	2	low	low	ADJ
bjp-19567	73	3	doses	dose	NOUN
bjp-19567	73	4	of	of	ADP
bjp-19567	73	5	nobiletin	nobiletin	NOUN
bjp-19567	73	6	(	(	PUNCT
bjp-19567	73	7	0.5	0.5	NUM
bjp-19567	73	8	,	,	PUNCT
bjp-19567	73	9	1	1	NUM
bjp-19567	73	10	and	and	CCONJ
bjp-19567	73	11	2.5	2.5	NUM
bjp-19567	73	12	µm	µm	NOUN
bjp-19567	73	13	)	)	PUNCT
bjp-19567	73	14	showed	show	VERB
bjp-19567	73	15	significant	significant	ADJ
bjp-19567	73	16	growth	growth	NOUN
bjp-19567	73	17	inhibitory	inhibitory	ADJ
bjp-19567	73	18	effect	effect	NOUN
bjp-19567	73	19	on	on	ADP
bjp-19567	73	20	saos-2	saos-2	NUM
bjp-19567	73	21	cells	cell	NOUN
bjp-19567	73	22	compared	compare	VERB
bjp-19567	73	23	to	to	PART
bjp-19567	73	24	control	control	VERB
bjp-19567	73	25	at	at	ADP
bjp-19567	73	26	72	72	NUM
bjp-19567	73	27	hours	hour	NOUN
bjp-19567	73	28	.	.	PUNCT
bjp-19567	74	1	in	in	ADP
bjp-19567	74	2	agreement	agreement	NOUN
bjp-19567	74	3	to	to	ADP
bjp-19567	74	4	mtt	mtt	NOUN
bjp-19567	74	5	assay	assay	VERB
bjp-19567	74	6	,	,	PUNCT
bjp-19567	74	7	dose	dose	NOUN
bjp-19567	74	8	-	-	PUNCT
bjp-19567	74	9	dependent	dependent	ADJ
bjp-19567	74	10	cell	cell	NOUN
bjp-19567	74	11	cytotoxicity	cytotoxicity	NOUN
bjp-19567	74	12	exerted	exert	VERB
bjp-19567	74	13	by	by	ADP
bjp-19567	74	14	nobiletin	nobiletin	NOUN
bjp-19567	74	15	was	be	AUX
bjp-19567	74	16	also	also	ADV
bjp-19567	74	17	demonstrated	demonstrate	VERB
bjp-19567	74	18	by	by	ADP
bjp-19567	74	19	ldh	ldh	PROPN
bjp-19567	74	20	assay	assay	PROPN
bjp-19567	74	21	(	(	PUNCT
bjp-19567	74	22	figure	figure	NOUN
bjp-19567	74	23	1b	1b	NUM
bjp-19567	74	24	)	)	PUNCT
bjp-19567	74	25	.	.	PUNCT
bjp-19567	75	1	to	to	PART
bjp-19567	75	2	examine	examine	VERB
bjp-19567	75	3	whether	whether	SCONJ
bjp-19567	75	4	nobiletin	nobiletin	ADJ
bjp-19567	75	5	treatment	treatment	NOUN
bjp-19567	75	6	could	could	AUX
bjp-19567	75	7	affect	affect	VERB
bjp-19567	75	8	cellcycle	cellcycle	NOUN
bjp-19567	75	9	progression	progression	NOUN
bjp-19567	75	10	and	and	CCONJ
bjp-19567	75	11	apoptosis	apoptosis	NOUN
bjp-19567	75	12	in	in	ADP
bjp-19567	75	13	osteosarcoma	osteosarcoma	ADJ
bjp-19567	75	14	cells	cell	NOUN
bjp-19567	75	15	,	,	PUNCT
bjp-19567	75	16	saos-2	saos-2	NUM
bjp-19567	75	17	cells	cell	NOUN
bjp-19567	75	18	were	be	AUX
bjp-19567	75	19	treated	treat	VERB
bjp-19567	75	20	with	with	ADP
bjp-19567	75	21	different	different	ADJ
bjp-19567	75	22	concentrations	concentration	NOUN
bjp-19567	75	23	of	of	ADP
bjp-19567	75	24	nobiletin	nobiletin	NOUN
bjp-19567	75	25	.	.	PUNCT
bjp-19567	76	1	rate	rate	NOUN
bjp-19567	76	2	of	of	ADP
bjp-19567	76	3	apoptosis	apoptosis	NOUN
bjp-19567	76	4	and	and	CCONJ
bjp-19567	76	5	phase	phase	NOUN
bjp-19567	76	6	of	of	ADP
bjp-19567	76	7	cell	cell	NOUN
bjp-19567	76	8	cycle	cycle	NOUN
bjp-19567	76	9	arrest	arrest	NOUN
bjp-19567	76	10	induced	induce	VERB
bjp-19567	76	11	by	by	ADP
bjp-19567	76	12	nobiletin	nobiletin	NOUN
bjp-19567	76	13	on	on	ADP
bjp-19567	76	14	saos-2	saos-2	NUM
bjp-19567	76	15	cells	cell	NOUN
bjp-19567	76	16	was	be	AUX
bjp-19567	76	17	analyzed	analyze	VERB
bjp-19567	76	18	using	use	VERB
bjp-19567	76	19	flow	flow	NOUN
bjp-19567	76	20	cytometry	cytometry	NOUN
bjp-19567	76	21	after	after	ADP
bjp-19567	76	22	24	24	NUM
bjp-19567	76	23	hours	hour	NOUN
bjp-19567	76	24	of	of	ADP
bjp-19567	76	25	treatment	treatment	NOUN
bjp-19567	76	26	.	.	PUNCT
bjp-19567	77	1	as	as	SCONJ
bjp-19567	77	2	shown	show	VERB
bjp-19567	77	3	in	in	ADP
bjp-19567	77	4	table	table	NOUN
bjp-19567	77	5	i	i	PRON
bjp-19567	77	6	,	,	PUNCT
bjp-19567	77	7	28.2	28.2	NUM
bjp-19567	77	8	±	±	NUM
bjp-19567	77	9	2.2	2.2	NUM
bjp-19567	77	10	%	%	NOUN
bjp-19567	77	11	increase	increase	NOUN
bjp-19567	77	12	in	in	ADP
bjp-19567	77	13	rate	rate	NOUN
bjp-19567	77	14	of	of	ADP
bjp-19567	77	15	apoptosis	apoptosis	NOUN
bjp-19567	77	16	was	be	AUX
bjp-19567	77	17	observed	observe	VERB
bjp-19567	77	18	after	after	ADP
bjp-19567	77	19	treatment	treatment	NOUN
bjp-19567	77	20	with	with	ADP
bjp-19567	77	21	10	10	NUM
bjp-19567	77	22	µm	µm	NOUN
bjp-19567	77	23	of	of	ADP
bjp-19567	77	24	nobiletin	nobiletin	NOUN
bjp-19567	77	25	(	(	PUNCT
bjp-19567	77	26	figure	figure	NOUN
bjp-19567	77	27	2a	2a	NUM
bjp-19567	77	28	)	)	PUNCT
bjp-19567	77	29	.	.	PUNCT
bjp-19567	78	1	in	in	ADP
bjp-19567	78	2	addition	addition	NOUN
bjp-19567	78	3	,	,	PUNCT
bjp-19567	78	4	cells	cell	NOUN
bjp-19567	78	5	treated	treat	VERB
bjp-19567	78	6	with	with	ADP
bjp-19567	78	7	lower	low	ADJ
bjp-19567	78	8	doses	dose	NOUN
bjp-19567	78	9	of	of	ADP
bjp-19567	78	10	nobiletin	nobiletin	NOUN
bjp-19567	78	11	also	also	ADV
bjp-19567	78	12	showed	show	VERB
bjp-19567	78	13	increased	increase	VERB
bjp-19567	78	14	rate	rate	NOUN
bjp-19567	78	15	of	of	ADP
bjp-19567	78	16	apoptosis	apoptosis	NOUN
bjp-19567	78	17	in	in	ADP
bjp-19567	78	18	a	a	DET
bjp-19567	78	19	dose	dose	NOUN
bjp-19567	78	20	-	-	PUNCT
bjp-19567	78	21	dependent	dependent	ADJ
bjp-19567	78	22	manner	manner	NOUN
bjp-19567	78	23	.	.	PUNCT
bjp-19567	79	1	an	an	DET
bjp-19567	79	2	increase	increase	NOUN
bjp-19567	79	3	in	in	ADP
bjp-19567	79	4	the	the	DET
bjp-19567	79	5	number	number	NOUN
bjp-19567	79	6	of	of	ADP
bjp-19567	79	7	cells	cell	NOUN
bjp-19567	79	8	arrested	arrest	VERB
bjp-19567	79	9	at	at	ADP
bjp-19567	79	10	g2	g2	PROPN
bjp-19567	79	11	/	/	SYM
bjp-19567	79	12	m	m	PROPN
bjp-19567	79	13	phase	phase	NOUN
bjp-19567	79	14	in	in	ADP
bjp-19567	79	15	saos-2	saos-2	NUM
bjp-19567	79	16	cells	cell	NOUN
bjp-19567	79	17	was	be	AUX
bjp-19567	79	18	observed	observe	VERB
bjp-19567	79	19	after	after	ADP
bjp-19567	79	20	treatment	treatment	NOUN
bjp-19567	79	21	of	of	ADP
bjp-19567	79	22	nobiletin	nobiletin	NOUN
bjp-19567	79	23	in	in	ADP
bjp-19567	79	24	a	a	DET
bjp-19567	79	25	dose	dose	ADJ
bjp-19567	79	26	-dependent	-dependent	ADJ
bjp-19567	79	27	manner	manner	NOUN
bjp-19567	79	28	(	(	PUNCT
bjp-19567	79	29	figure	figure	NOUN
bjp-19567	79	30	2b	2b	NOUN
bjp-19567	79	31	)	)	PUNCT
bjp-19567	79	32	.	.	PUNCT
bjp-19567	80	1	following	follow	VERB
bjp-19567	80	2	24	24	NUM
bjp-19567	80	3	hours	hour	NOUN
bjp-19567	80	4	treatment	treatment	NOUN
bjp-19567	80	5	of	of	ADP
bjp-19567	80	6	saos-2	saos-2	NUM
bjp-19567	80	7	cells	cell	NOUN
bjp-19567	80	8	with	with	ADP
bjp-19567	80	9	different	different	ADJ
bjp-19567	80	10	doses	dose	NOUN
bjp-19567	80	11	of	of	ADP
bjp-19567	80	12	nobiletin	nobiletin	NOUN
bjp-19567	80	13	,	,	PUNCT
bjp-19567	80	14	caspase-9	caspase-9	PROPN
bjp-19567	80	15	and	and	CCONJ
bjp-19567	80	16	-3	-3	PUNCT
bjp-19567	80	17	activities	activity	NOUN
bjp-19567	80	18	were	be	AUX
bjp-19567	80	19	determined	determine	VERB
bjp-19567	80	20	.	.	PUNCT
bjp-19567	81	1	results	result	NOUN
bjp-19567	81	2	demonstrated	demonstrate	VERB
bjp-19567	81	3	a	a	DET
bjp-19567	81	4	significant	significant	ADJ
bjp-19567	81	5	increase	increase	NOUN
bjp-19567	81	6	of	of	ADP
bjp-19567	81	7	caspase-9	caspase-9	PROPN
bjp-19567	81	8	and	and	CCONJ
bjp-19567	81	9	-3	-3	PUNCT
bjp-19567	81	10	activities	activity	NOUN
bjp-19567	81	11	after	after	ADP
bjp-19567	81	12	stimulation	stimulation	NOUN
bjp-19567	81	13	with	with	ADP
bjp-19567	81	14	nobiletin	nobiletin	NOUN
bjp-19567	81	15	(	(	PUNCT
bjp-19567	81	16	figure	figure	NOUN
bjp-19567	81	17	3	3	NUM
bjp-19567	81	18	)	)	PUNCT
bjp-19567	81	19	.	.	PUNCT
bjp-19567	82	1	a	a	DET
bjp-19567	82	2	dose	dose	NOUN
bjp-19567	82	3	-	-	PUNCT
bjp-19567	82	4	dependent	dependent	ADJ
bjp-19567	82	5	increase	increase	NOUN
bjp-19567	82	6	in	in	ADP
bjp-19567	82	7	activities	activity	NOUN
bjp-19567	82	8	was	be	AUX
bjp-19567	82	9	observed	observe	VERB
bjp-19567	82	10	for	for	ADP
bjp-19567	82	11	both	both	PRON
bjp-19567	82	12	,	,	PUNCT
bjp-19567	82	13	caspase-9	caspase-9	PROPN
bjp-19567	82	14	and	and	CCONJ
bjp-19567	82	15	-3	-3	INTJ
bjp-19567	82	16	,	,	PUNCT
bjp-19567	82	17	after	after	ADP
bjp-19567	82	18	24	24	NUM
bjp-19567	82	19	hours	hour	NOUN
bjp-19567	82	20	of	of	ADP
bjp-19567	82	21	stimulation	stimulation	NOUN
bjp-19567	82	22	with	with	ADP
bjp-19567	82	23	nobiletin	nobiletin	NOUN
bjp-19567	82	24	in	in	ADP
bjp-19567	82	25	saos-2	saos-2	NUM
bjp-19567	82	26	cells	cell	NOUN
bjp-19567	82	27	(	(	PUNCT
bjp-19567	82	28	figure	figure	NOUN
bjp-19567	82	29	3a	3a	NUM
bjp-19567	82	30	and	and	CCONJ
bjp-19567	82	31	b	b	NOUN
bjp-19567	82	32	)	)	PUNCT
bjp-19567	82	33	.	.	PUNCT
bjp-19567	83	1	an	an	DET
bjp-19567	83	2	increment	increment	NOUN
bjp-19567	83	3	in	in	ADP
bjp-19567	83	4	the	the	DET
bjp-19567	83	5	caspase-9	caspase-9	PROPN
bjp-19567	83	6	and	and	CCONJ
bjp-19567	83	7	3	3	NUM
bjp-19567	83	8	activity	activity	NOUN
bjp-19567	83	9	points	point	NOUN
bjp-19567	83	10	toward	toward	ADP
bjp-19567	83	11	a	a	DET
bjp-19567	83	12	caspase-9	caspase-9	PROPN
bjp-19567	83	13	and	and	CCONJ
bjp-19567	83	14	-3	-3	X
bjp-19567	83	15	dependent	dependent	ADJ
bjp-19567	83	16	signaling	signal	VERB
bjp-19567	83	17	in	in	ADP
bjp-19567	83	18	saos-2	saos-2	NUM
bjp-19567	83	19	cells	cell	NOUN
bjp-19567	83	20	for	for	ADP
bjp-19567	83	21	inducing	induce	VERB
bjp-19567	83	22	apoptosis	apoptosis	NOUN
bjp-19567	83	23	by	by	ADP
bjp-19567	83	24	nobiletin	nobiletin	NOUN
bjp-19567	83	25	.	.	PUNCT
bjp-19567	84	1	results	result	NOUN
bjp-19567	84	2	from	from	ADP
bjp-19567	84	3	western	western	ADJ
bjp-19567	84	4	blotting	blotting	NOUN
bjp-19567	84	5	showed	show	VERB
bjp-19567	84	6	(	(	PUNCT
bjp-19567	84	7	figure	figure	NOUN
bjp-19567	84	8	4	4	NUM
bjp-19567	84	9	)	)	PUNCT
bjp-19567	84	10	that	that	SCONJ
bjp-19567	84	11	the	the	DET
bjp-19567	84	12	protein	protein	NOUN
bjp-19567	84	13	levels	level	NOUN
bjp-19567	84	14	of	of	ADP
bjp-19567	84	15	p	p	PROPN
bjp-19567	84	16	-	-	PUNCT
bjp-19567	84	17	erk	erk	PROPN
bjp-19567	84	18	were	be	AUX
bjp-19567	84	19	upregulated	upregulate	VERB
bjp-19567	84	20	in	in	ADP
bjp-19567	84	21	saos-2	saos-2	NUM
bjp-19567	84	22	cells	cell	NOUN
bjp-19567	84	23	after	after	ADP
bjp-19567	84	24	treatment	treatment	NOUN
bjp-19567	84	25	with	with	ADP
bjp-19567	84	26	nobiletin	nobiletin	NOUN
bjp-19567	84	27	,	,	PUNCT
bjp-19567	84	28	but	but	CCONJ
bjp-19567	84	29	that	that	PRON
bjp-19567	84	30	of	of	ADP
bjp-19567	84	31	p	p	PROPN
bjp-19567	84	32	-	-	PUNCT
bjp-19567	84	33	akt	akt	PROPN
bjp-19567	84	34	408	408	NUM
bjp-19567	84	35	bangladesh	bangladesh	PROPN
bjp-19567	84	36	j	j	PROPN
bjp-19567	84	37	pharmacol	pharmacol	PROPN
bjp-19567	84	38	2014	2014	NUM
bjp-19567	84	39	;	;	PUNCT
bjp-19567	84	40	9	9	NUM
bjp-19567	84	41	:	:	SYM
bjp-19567	84	42	406	406	NUM
bjp-19567	84	43	-	-	SYM
bjp-19567	84	44	412	412	NUM
bjp-19567	84	45	figure	figure	NOUN
bjp-19567	84	46	1	1	NUM
bjp-19567	84	47	:	:	PUNCT
bjp-19567	84	48	anti	anti	ADJ
bjp-19567	84	49	-	-	ADJ
bjp-19567	84	50	proliferative	proliferative	ADJ
bjp-19567	84	51	effect	effect	NOUN
bjp-19567	84	52	of	of	ADP
bjp-19567	84	53	nobiletin	nobiletin	NOUN
bjp-19567	84	54	at	at	ADP
bjp-19567	84	55	different	different	ADJ
bjp-19567	84	56	concentrations	concentration	NOUN
bjp-19567	84	57	on	on	ADP
bjp-19567	84	58	saos-2	saos-2	NUM
bjp-19567	84	59	cells	cell	NOUN
bjp-19567	84	60	(	(	PUNCT
bjp-19567	84	61	a	a	X
bjp-19567	84	62	)	)	PUNCT
bjp-19567	84	63	mtt	mtt	NOUN
bjp-19567	84	64	assay	assay	NOUN
bjp-19567	84	65	(	(	PUNCT
bjp-19567	84	66	b	b	X
bjp-19567	84	67	)	)	PUNCT
bjp-19567	84	68	ldh	ldh	NOUN
bjp-19567	84	69	assay	assay	ADV
bjp-19567	85	1	a	a	DET
bjp-19567	85	2	b	b	NOUN
bjp-19567	85	3	was	be	AUX
bjp-19567	85	4	down	down	ADV
bjp-19567	85	5	-	-	PUNCT
bjp-19567	85	6	regulated	regulate	VERB
bjp-19567	85	7	.	.	PUNCT
bjp-19567	86	1	phosphorylation	phosphorylation	NOUN
bjp-19567	86	2	of	of	ADP
bjp-19567	86	3	erk	erk	PROPN
bjp-19567	86	4	molecules	molecule	NOUN
bjp-19567	86	5	were	be	AUX
bjp-19567	86	6	in	in	ADP
bjp-19567	86	7	a	a	DET
bjp-19567	86	8	dose	dose	NOUN
bjp-19567	86	9	-	-	PUNCT
bjp-19567	86	10	dependent	dependent	ADJ
bjp-19567	86	11	manner	manner	NOUN
bjp-19567	86	12	after	after	ADP
bjp-19567	86	13	24	24	NUM
bjp-19567	86	14	hours	hour	NOUN
bjp-19567	86	15	of	of	ADP
bjp-19567	86	16	treatment	treatment	NOUN
bjp-19567	86	17	.	.	PUNCT
bjp-19567	87	1	similarly	similarly	ADV
bjp-19567	87	2	,	,	PUNCT
bjp-19567	87	3	a	a	DET
bjp-19567	87	4	dose	dose	NOUN
bjp-19567	87	5	-	-	PUNCT
bjp-19567	87	6	dependent	dependent	ADJ
bjp-19567	87	7	suppression	suppression	NOUN
bjp-19567	87	8	of	of	ADP
bjp-19567	87	9	phosphorylation	phosphorylation	NOUN
bjp-19567	87	10	of	of	ADP
bjp-19567	87	11	akt	akt	PROPN
bjp-19567	87	12	molecule	molecule	NOUN
bjp-19567	87	13	was	be	AUX
bjp-19567	87	14	observed	observe	VERB
bjp-19567	87	15	after	after	ADP
bjp-19567	87	16	24	24	NUM
bjp-19567	87	17	hours	hour	NOUN
bjp-19567	87	18	of	of	ADP
bjp-19567	87	19	treatment	treatment	NOUN
bjp-19567	87	20	.	.	PUNCT
bjp-19567	88	1	in	in	ADP
bjp-19567	88	2	order	order	NOUN
bjp-19567	88	3	to	to	PART
bjp-19567	88	4	substantiate	substantiate	VERB
bjp-19567	88	5	our	our	PRON
bjp-19567	88	6	results	result	NOUN
bjp-19567	88	7	that	that	SCONJ
bjp-19567	88	8	nobiletin	nobiletin	NOUN
bjp-19567	88	9	mediates	mediate	NOUN
bjp-19567	88	10	it	it	PRON
bjp-19567	88	11	anti	anti	ADJ
bjp-19567	88	12	-	-	ADJ
bjp-19567	88	13	proliferative	proliferative	ADJ
bjp-19567	88	14	effect	effect	NOUN
bjp-19567	88	15	through	through	ADP
bjp-19567	88	16	activation	activation	NOUN
bjp-19567	88	17	of	of	ADP
bjp-19567	88	18	erk	erk	NOUN
bjp-19567	88	19	signaling	signal	VERB
bjp-19567	88	20	pathway	pathway	NOUN
bjp-19567	88	21	and	and	CCONJ
bjp-19567	88	22	suppression	suppression	NOUN
bjp-19567	88	23	of	of	ADP
bjp-19567	88	24	akt	akt	PROPN
bjp-19567	88	25	signaling	signal	VERB
bjp-19567	88	26	,	,	PUNCT
bjp-19567	88	27	we	we	PRON
bjp-19567	88	28	tried	try	VERB
bjp-19567	88	29	to	to	PART
bjp-19567	88	30	inhibit	inhibit	VERB
bjp-19567	88	31	the	the	DET
bjp-19567	88	32	activation	activation	NOUN
bjp-19567	88	33	of	of	ADP
bjp-19567	88	34	erk	erk	PROPN
bjp-19567	88	35	pathway	pathway	NOUN
bjp-19567	88	36	by	by	ADP
bjp-19567	88	37	pd	pd	PROPN
bjp-19567	88	38	98059	98059	NUM
bjp-19567	88	39	and	and	CCONJ
bjp-19567	88	40	restore	restore	VERB
bjp-19567	88	41	akt	akt	NOUN
bjp-19567	88	42	signaling	signal	VERB
bjp-19567	88	43	in	in	ADP
bjp-19567	88	44	saos-2	saos-2	NUM
bjp-19567	88	45	by	by	ADP
bjp-19567	88	46	constitutive	constitutive	ADJ
bjp-19567	88	47	expression	expression	NOUN
bjp-19567	88	48	of	of	ADP
bjp-19567	88	49	akt	akt	PROPN
bjp-19567	88	50	molecule	molecule	NOUN
bjp-19567	88	51	in	in	ADP
bjp-19567	88	52	presence	presence	NOUN
bjp-19567	88	53	of	of	ADP
bjp-19567	88	54	nobiletin	nobiletin	NOUN
bjp-19567	88	55	.	.	PUNCT
bjp-19567	89	1	erk	erk	PROPN
bjp-19567	89	2	signaling	signal	VERB
bjp-19567	89	3	pathways	pathway	NOUN
bjp-19567	89	4	was	be	AUX
bjp-19567	89	5	inhibited	inhibit	VERB
bjp-19567	89	6	by	by	ADP
bjp-19567	89	7	well	well	ADV
bjp-19567	89	8	-	-	PUNCT
bjp-19567	89	9	known	know	VERB
bjp-19567	89	10	mek	mek	PROPN
bjp-19567	89	11	inhibitor	inhibitor	NOUN
bjp-19567	89	12	,	,	PUNCT
bjp-19567	89	13	pd98059	pd98059	NOUN
bjp-19567	89	14	(	(	PUNCT
bjp-19567	89	15	5	5	NUM
bjp-19567	89	16	μm	μm	NUM
bjp-19567	89	17	)	)	PUNCT
bjp-19567	89	18	,	,	PUNCT
bjp-19567	89	19	for	for	ADP
bjp-19567	89	20	30	30	NUM
bjp-19567	89	21	min	min	NOUN
bjp-19567	89	22	prior	prior	ADV
bjp-19567	89	23	to	to	ADP
bjp-19567	89	24	the	the	DET
bjp-19567	89	25	treatment	treatment	NOUN
bjp-19567	89	26	of	of	ADP
bjp-19567	89	27	nobiletin	nobiletin	NOUN
bjp-19567	89	28	(	(	PUNCT
bjp-19567	89	29	5	5	NUM
bjp-19567	89	30	μm	μm	NUM
bjp-19567	89	31	)	)	PUNCT
bjp-19567	89	32	to	to	ADP
bjp-19567	89	33	saos-2	saos-2	NUM
bjp-19567	89	34	cells	cell	NOUN
bjp-19567	89	35	.	.	PUNCT
bjp-19567	90	1	after	after	ADP
bjp-19567	90	2	24	24	NUM
bjp-19567	90	3	hours	hour	NOUN
bjp-19567	90	4	of	of	ADP
bjp-19567	90	5	treatment	treatment	NOUN
bjp-19567	90	6	,	,	PUNCT
bjp-19567	90	7	mtt	mtt	PROPN
bjp-19567	90	8	assay	assay	NOUN
bjp-19567	90	9	was	be	AUX
bjp-19567	90	10	performed	perform	VERB
bjp-19567	90	11	to	to	PART
bjp-19567	90	12	assess	assess	VERB
bjp-19567	90	13	the	the	DET
bjp-19567	90	14	cell	cell	NOUN
bjp-19567	90	15	viability	viability	NOUN
bjp-19567	90	16	of	of	ADP
bjp-19567	90	17	the	the	DET
bjp-19567	90	18	treated	treat	VERB
bjp-19567	90	19	cells	cell	NOUN
bjp-19567	90	20	.	.	PUNCT
bjp-19567	91	1	as	as	SCONJ
bjp-19567	91	2	shown	show	VERB
bjp-19567	91	3	in	in	ADP
bjp-19567	91	4	figure	figure	NOUN
bjp-19567	91	5	5a	5a	NUM
bjp-19567	91	6	,	,	PUNCT
bjp-19567	91	7	nobiletin	nobiletin	NOUN
bjp-19567	91	8	(	(	PUNCT
bjp-19567	91	9	5	5	NUM
bjp-19567	91	10	μm	μm	NOUN
bjp-19567	91	11	)	)	PUNCT
bjp-19567	91	12	was	be	AUX
bjp-19567	91	13	able	able	ADJ
bjp-19567	91	14	to	to	PART
bjp-19567	91	15	induce	induce	VERB
bjp-19567	91	16	50	50	NUM
bjp-19567	91	17	%	%	NOUN
bjp-19567	91	18	decrease	decrease	NOUN
bjp-19567	91	19	in	in	ADP
bjp-19567	91	20	cell	cell	NOUN
bjp-19567	91	21	viability	viability	NOUN
bjp-19567	91	22	compared	compare	VERB
bjp-19567	91	23	to	to	ADP
bjp-19567	91	24	control	control	NOUN
bjp-19567	91	25	whereas	whereas	SCONJ
bjp-19567	91	26	prior	prior	ADJ
bjp-19567	91	27	blocking	blocking	NOUN
bjp-19567	91	28	of	of	ADP
bjp-19567	91	29	erk	erk	NOUN
bjp-19567	91	30	signaling	signal	VERB
bjp-19567	91	31	by	by	ADP
bjp-19567	91	32	pd98059	pd98059	NOUN
bjp-19567	91	33	dramatically	dramatically	ADV
bjp-19567	91	34	reversed	reverse	VERB
bjp-19567	91	35	the	the	DET
bjp-19567	91	36	cytotoxicity	cytotoxicity	NOUN
bjp-19567	91	37	induced	induce	VERB
bjp-19567	91	38	by	by	ADP
bjp-19567	91	39	nobiletin	nobiletin	NOUN
bjp-19567	91	40	in	in	ADP
bjp-19567	91	41	comparison	comparison	NOUN
bjp-19567	91	42	to	to	ADP
bjp-19567	91	43	only	only	ADV
bjp-19567	91	44	nobiletin	nobiletin	NOUN
bjp-19567	91	45	treated	treat	VERB
bjp-19567	91	46	saos-2	saos-2	NUM
bjp-19567	91	47	cells	cell	NOUN
bjp-19567	91	48	.	.	PUNCT
bjp-19567	92	1	to	to	PART
bjp-19567	92	2	deduce	deduce	VERB
bjp-19567	92	3	the	the	DET
bjp-19567	92	4	role	role	NOUN
bjp-19567	92	5	akt	akt	NOUN
bjp-19567	92	6	signaling	signal	VERB
bjp-19567	92	7	pathway	pathway	NOUN
bjp-19567	92	8	,	,	PUNCT
bjp-19567	92	9	saos-2	saos-2	NUM
bjp-19567	92	10	cells	cell	NOUN
bjp-19567	92	11	were	be	AUX
bjp-19567	92	12	transiently	transiently	ADV
bjp-19567	92	13	bangladesh	bangladesh	ADJ
bjp-19567	92	14	j	j	PROPN
bjp-19567	92	15	pharmacol	pharmacol	PROPN
bjp-19567	92	16	2014	2014	NUM
bjp-19567	92	17	;	;	PUNCT
bjp-19567	92	18	9	9	NUM
bjp-19567	92	19	:	:	SYM
bjp-19567	92	20	406	406	NUM
bjp-19567	92	21	-	-	SYM
bjp-19567	92	22	412	412	NUM
bjp-19567	92	23	409	409	NUM
bjp-19567	92	24	a	a	PRON
bjp-19567	92	25	a	a	DET
bjp-19567	92	26	a	a	DET
bjp-19567	92	27	a	a	DET
bjp-19567	92	28	b	b	PROPN
bjp-19567	92	29	b	b	PROPN
bjp-19567	92	30	b	b	PROPN
bjp-19567	92	31	c	c	PROPN
bjp-19567	92	32	a	a	DET
bjp-19567	92	33	a	a	DET
bjp-19567	92	34	b	b	PROPN
bjp-19567	92	35	b	b	PROPN
bjp-19567	92	36	b	b	PROPN
bjp-19567	92	37	b	b	PROPN
bjp-19567	92	38	b	b	PROPN
bjp-19567	92	39	b	b	PROPN
bjp-19567	92	40	b	b	PROPN
bjp-19567	92	41	b	b	PROPN
bjp-19567	92	42	table	table	NOUN
bjp-19567	92	43	i	i	PRON
bjp-19567	92	44	the	the	DET
bjp-19567	92	45	cell	cell	NOUN
bjp-19567	92	46	cycle	cycle	NOUN
bjp-19567	92	47	and	and	CCONJ
bjp-19567	92	48	apoptosis	apoptosis	NOUN
bjp-19567	92	49	ratios	ratio	NOUN
bjp-19567	92	50	with	with	ADP
bjp-19567	92	51	various	various	ADJ
bjp-19567	92	52	concentrations	concentration	NOUN
bjp-19567	92	53	of	of	ADP
bjp-19567	92	54	nobiletin	nobiletin	NOUN
bjp-19567	92	55	on	on	ADP
bjp-19567	92	56	saso-2	saso-2	NUM
bjp-19567	92	57	cells	cell	NOUN
bjp-19567	92	58	group	group	NOUN
bjp-19567	92	59	concentration	concentration	NOUN
bjp-19567	92	60	(	(	PUNCT
bjp-19567	92	61	μm	μm	X
bjp-19567	92	62	)	)	PUNCT
bjp-19567	92	63	go	go	VERB
bjp-19567	92	64	/	/	SYM
bjp-19567	92	65	g1	g1	PROPN
bjp-19567	92	66	(	(	PUNCT
bjp-19567	92	67	%	%	INTJ
bjp-19567	92	68	)	)	PUNCT
bjp-19567	92	69	s	s	PROPN
bjp-19567	92	70	(	(	PUNCT
bjp-19567	92	71	%	%	INTJ
bjp-19567	92	72	)	)	PUNCT
bjp-19567	93	1	g2	g2	PROPN
bjp-19567	93	2	/	/	SYM
bjp-19567	93	3	m	m	PROPN
bjp-19567	93	4	(	(	PUNCT
bjp-19567	93	5	%	%	NOUN
bjp-19567	93	6	)	)	PUNCT
bjp-19567	93	7	apoptosis	apoptosis	NOUN
bjp-19567	93	8	ratio	ratio	NOUN
bjp-19567	93	9	(	(	PUNCT
bjp-19567	93	10	%	%	INTJ
bjp-19567	93	11	)	)	PUNCT
bjp-19567	93	12	nobiletin	nobiletin	NOUN
bjp-19567	93	13	0	0	NUM
bjp-19567	93	14	58.5	58.5	NUM
bjp-19567	93	15	±	±	NUM
bjp-19567	93	16	1.5	1.5	NUM
bjp-19567	93	17	30.5	30.5	NUM
bjp-19567	93	18	±	±	NUM
bjp-19567	93	19	2.7	2.7	NUM
bjp-19567	93	20	10.9	10.9	NUM
bjp-19567	93	21	±	±	NUM
bjp-19567	93	22	0.7	0.7	NUM
bjp-19567	93	23	2.2	2.2	NUM
bjp-19567	93	24	±	±	NUM
bjp-19567	93	25	0.0	0.0	NUM
bjp-19567	93	26	0.5	0.5	NUM
bjp-19567	93	27	56.2	56.2	NUM
bjp-19567	93	28	±	±	NUM
bjp-19567	93	29	1.4	1.4	NUM
bjp-19567	93	30	32.5	32.5	NUM
bjp-19567	93	31	±	±	NUM
bjp-19567	93	32	2.6	2.6	NUM
bjp-19567	93	33	11.2	11.2	NUM
bjp-19567	93	34	±	±	NUM
bjp-19567	93	35	0.8	0.8	NUM
bjp-19567	93	36	2.9	2.9	NUM
bjp-19567	93	37	±	±	NUM
bjp-19567	93	38	0.1	0.1	NUM
bjp-19567	93	39	1.0	1.0	NUM
bjp-19567	93	40	54.9	54.9	NUM
bjp-19567	93	41	±	±	NUM
bjp-19567	93	42	1.4	1.4	NUM
bjp-19567	93	43	29.3	29.3	NUM
bjp-19567	93	44	±	±	NUM
bjp-19567	93	45	2.3	2.3	NUM
bjp-19567	93	46	15.7	15.7	NUM
bjp-19567	93	47	±	±	NUM
bjp-19567	93	48	0.8	0.8	NUM
bjp-19567	93	49	6.3	6.3	NUM
bjp-19567	93	50	±	±	NUM
bjp-19567	93	51	0.0	0.0	NUM
bjp-19567	93	52	2.5	2.5	NUM
bjp-19567	93	53	50.6	50.6	NUM
bjp-19567	93	54	±	±	NUM
bjp-19567	93	55	2.0	2.0	NUM
bjp-19567	93	56	30.4	30.4	NUM
bjp-19567	93	57	±	±	NUM
bjp-19567	93	58	3.6	3.6	NUM
bjp-19567	93	59	18.8	18.8	NUM
bjp-19567	93	60	±	±	NUM
bjp-19567	93	61	1.3	1.3	NUM
bjp-19567	93	62	11.5	11.5	NUM
bjp-19567	93	63	±	±	NUM
bjp-19567	93	64	1.9	1.9	NUM
bjp-19567	93	65	5.0	5.0	NUM
bjp-19567	93	66	47.9	47.9	NUM
bjp-19567	93	67	±	±	NUM
bjp-19567	93	68	1.3	1.3	NUM
bjp-19567	93	69	27.4	27.4	NUM
bjp-19567	93	70	±	±	NUM
bjp-19567	93	71	1.9	1.9	NUM
bjp-19567	93	72	22.6	22.6	NUM
bjp-19567	93	73	±	±	NUM
bjp-19567	93	74	0.7	0.7	NUM
bjp-19567	93	75	22.1	22.1	NUM
bjp-19567	93	76	±	±	NUM
bjp-19567	93	77	1.6	1.6	NUM
bjp-19567	93	78	10	10	NUM
bjp-19567	93	79	47.3	47.3	NUM
bjp-19567	93	80	±	±	NUM
bjp-19567	93	81	2.1	2.1	NUM
bjp-19567	93	82	28.2	28.2	NUM
bjp-19567	93	83	±	±	NUM
bjp-19567	93	84	3.2	3.2	NUM
bjp-19567	93	85	24.4	24.4	NUM
bjp-19567	93	86	±	±	NUM
bjp-19567	93	87	1.2	1.2	NUM
bjp-19567	93	88	28.2	28.2	NUM
bjp-19567	93	89	±	±	NUM
bjp-19567	93	90	2.2	2.2	NUM
bjp-19567	93	91	figure	figure	NOUN
bjp-19567	93	92	2	2	NUM
bjp-19567	93	93	:	:	PUNCT
bjp-19567	93	94	effect	effect	NOUN
bjp-19567	93	95	of	of	ADP
bjp-19567	93	96	nobiletin	nobiletin	NOUN
bjp-19567	93	97	treated	treat	VERB
bjp-19567	93	98	for	for	ADP
bjp-19567	93	99	24	24	NUM
bjp-19567	93	100	hours	hour	NOUN
bjp-19567	93	101	at	at	ADP
bjp-19567	93	102	different	different	ADJ
bjp-19567	93	103	concentration	concentration	NOUN
bjp-19567	93	104	(	(	PUNCT
bjp-19567	93	105	0	0	NUM
bjp-19567	93	106	,	,	PUNCT
bjp-19567	93	107	0.5	0.5	NUM
bjp-19567	93	108	,	,	PUNCT
bjp-19567	93	109	1	1	NUM
bjp-19567	93	110	,	,	PUNCT
bjp-19567	93	111	2.5	2.5	NUM
bjp-19567	93	112	,	,	PUNCT
bjp-19567	93	113	5	5	NUM
bjp-19567	93	114	and	and	CCONJ
bjp-19567	93	115	10	10	NUM
bjp-19567	93	116	μm	μm	NUM
bjp-19567	93	117	)	)	PUNCT
bjp-19567	93	118	on	on	ADP
bjp-19567	93	119	apoptosis	apoptosis	NOUN
bjp-19567	93	120	and	and	CCONJ
bjp-19567	93	121	cell	cell	NOUN
bjp-19567	93	122	cycle	cycle	NOUN
bjp-19567	93	123	arrest	arrest	NOUN
bjp-19567	93	124	.	.	PUNCT
bjp-19567	94	1	(	(	PUNCT
bjp-19567	94	2	a	a	X
bjp-19567	94	3	)	)	PUNCT
bjp-19567	94	4	nobiletin	nobiletin	NOUN
bjp-19567	94	5	induces	induce	VERB
bjp-19567	94	6	apoptosis	apoptosis	NOUN
bjp-19567	94	7	ratio	ratio	NOUN
bjp-19567	94	8	in	in	ADP
bjp-19567	94	9	saos-2	saos-2	NUM
bjp-19567	94	10	cells	cell	NOUN
bjp-19567	94	11	;	;	PUNCT
bjp-19567	94	12	(	(	PUNCT
bjp-19567	94	13	b	b	X
bjp-19567	94	14	)	)	PUNCT
bjp-19567	94	15	cell	cell	NOUN
bjp-19567	94	16	cycle	cycle	NOUN
bjp-19567	94	17	distribution	distribution	NOUN
bjp-19567	94	18	after	after	ADP
bjp-19567	94	19	treatment	treatment	NOUN
bjp-19567	94	20	of	of	ADP
bjp-19567	94	21	saos-2	saos-2	NUM
bjp-19567	94	22	cells	cell	NOUN
bjp-19567	94	23	with	with	ADP
bjp-19567	94	24	varying	vary	VERB
bjp-19567	94	25	doses	dose	NOUN
bjp-19567	94	26	of	of	ADP
bjp-19567	94	27	nobiletin	nobiletin	NOUN
bjp-19567	94	28	.	.	PUNCT
bjp-19567	95	1	three	three	NUM
bjp-19567	95	2	independent	independent	ADJ
bjp-19567	95	3	experiments	experiment	NOUN
bjp-19567	95	4	were	be	AUX
bjp-19567	95	5	performed	perform	VERB
bjp-19567	95	6	and	and	CCONJ
bjp-19567	95	7	data	datum	NOUN
bjp-19567	95	8	is	be	AUX
bjp-19567	95	9	expressed	express	VERB
bjp-19567	95	10	as	as	ADP
bjp-19567	95	11	their	their	PRON
bjp-19567	95	12	mean	mean	ADJ
bjp-19567	95	13	±	±	NUM
bjp-19567	95	14	sd	sd	NOUN
bjp-19567	95	15	(	(	PUNCT
bjp-19567	95	16	ap<0.01	ap<0.01	PROPN
bjp-19567	95	17	,	,	PUNCT
bjp-19567	95	18	bp<0.001	bp<0.001	NOUN
bjp-19567	95	19	)	)	PUNCT
bjp-19567	95	20	figure	figure	NOUN
bjp-19567	95	21	3	3	NUM
bjp-19567	95	22	:	:	PUNCT
bjp-19567	95	23	activation	activation	NOUN
bjp-19567	95	24	of	of	ADP
bjp-19567	95	25	caspase	caspase	NOUN
bjp-19567	95	26	activity	activity	NOUN
bjp-19567	95	27	after	after	ADP
bjp-19567	95	28	24	24	NUM
bjp-19567	95	29	hours	hour	NOUN
bjp-19567	95	30	of	of	ADP
bjp-19567	95	31	treatment	treatment	NOUN
bjp-19567	95	32	with	with	ADP
bjp-19567	95	33	varying	vary	VERB
bjp-19567	95	34	doses	dose	NOUN
bjp-19567	95	35	of	of	ADP
bjp-19567	95	36	nobiletin	nobiletin	NOUN
bjp-19567	95	37	,	,	PUNCT
bjp-19567	95	38	(	(	PUNCT
bjp-19567	95	39	a	a	X
bjp-19567	95	40	)	)	PUNCT
bjp-19567	95	41	caspase-9	caspase-9	PROPN
bjp-19567	95	42	and	and	CCONJ
bjp-19567	95	43	(	(	PUNCT
bjp-19567	95	44	b	b	NOUN
bjp-19567	95	45	)	)	PUNCT
bjp-19567	95	46	caspase3	caspase3	NOUN
bjp-19567	95	47	activity	activity	NOUN
bjp-19567	95	48	.	.	PUNCT
bjp-19567	96	1	three	three	NUM
bjp-19567	96	2	independent	independent	ADJ
bjp-19567	96	3	experiments	experiment	NOUN
bjp-19567	96	4	were	be	AUX
bjp-19567	96	5	performed	perform	VERB
bjp-19567	96	6	and	and	CCONJ
bjp-19567	96	7	data	datum	NOUN
bjp-19567	96	8	is	be	AUX
bjp-19567	96	9	expressed	express	VERB
bjp-19567	96	10	as	as	ADP
bjp-19567	96	11	their	their	PRON
bjp-19567	96	12	mean	mean	ADJ
bjp-19567	96	13	±	±	NUM
bjp-19567	96	14	sd	sd	NOUN
bjp-19567	96	15	(	(	PUNCT
bjp-19567	96	16	ap<0.01	ap<0.01	PROPN
bjp-19567	96	17	,	,	PUNCT
bjp-19567	96	18	bp<0.001	bp<0.001	PROPN
bjp-19567	96	19	)	)	PUNCT
bjp-19567	96	20	transfected	transfecte	VERB
bjp-19567	96	21	with	with	ADP
bjp-19567	96	22	myraktdeltaph	myraktdeltaph	NOUN
bjp-19567	96	23	plasmid	plasmid	NOUN
bjp-19567	96	24	dna	dna	PROPN
bjp-19567	96	25	followed	follow	VERB
bjp-19567	96	26	by	by	ADP
bjp-19567	96	27	treatment	treatment	NOUN
bjp-19567	96	28	of	of	ADP
bjp-19567	96	29	nobiletin	nobiletin	NOUN
bjp-19567	96	30	for	for	ADP
bjp-19567	96	31	24	24	NUM
bjp-19567	96	32	hours	hour	NOUN
bjp-19567	96	33	.	.	PUNCT
bjp-19567	97	1	expression	expression	NOUN
bjp-19567	97	2	of	of	ADP
bjp-19567	97	3	constitutive	constitutive	ADJ
bjp-19567	97	4	form	form	NOUN
bjp-19567	97	5	of	of	ADP
bjp-19567	97	6	akt	akt	PROPN
bjp-19567	97	7	inside	inside	ADP
bjp-19567	97	8	the	the	DET
bjp-19567	97	9	saos-2	saos-2	NUM
bjp-19567	97	10	cells	cell	NOUN
bjp-19567	97	11	nullified	nullify	VERB
bjp-19567	97	12	the	the	DET
bjp-19567	97	13	anti	anti	ADJ
bjp-19567	97	14	-	-	ADJ
bjp-19567	97	15	proliferative	proliferative	ADJ
bjp-19567	97	16	effect	effect	NOUN
bjp-19567	97	17	of	of	ADP
bjp-19567	97	18	nobiletin	nobiletin	NOUN
bjp-19567	97	19	(	(	PUNCT
bjp-19567	97	20	figure	figure	NOUN
bjp-19567	97	21	5b	5b	NUM
bjp-19567	97	22	)	)	PUNCT
bjp-19567	97	23	,	,	PUNCT
bjp-19567	97	24	restoring	restore	VERB
bjp-19567	97	25	proliferative	proliferative	ADJ
bjp-19567	97	26	character	character	NOUN
bjp-19567	97	27	of	of	ADP
bjp-19567	97	28	saos-2	saos-2	NUM
bjp-19567	97	29	cells	cell	NOUN
bjp-19567	97	30	.	.	PUNCT
bjp-19567	98	1	discussion	discussion	NOUN
bjp-19567	98	2	dietary	dietary	ADJ
bjp-19567	98	3	phytochemicals	phytochemical	NOUN
bjp-19567	98	4	has	have	AUX
bjp-19567	98	5	been	be	AUX
bjp-19567	98	6	shown	show	VERB
bjp-19567	98	7	to	to	PART
bjp-19567	98	8	possess	possess	VERB
bjp-19567	98	9	various	various	ADJ
bjp-19567	98	10	beneficial	beneficial	ADJ
bjp-19567	98	11	biological	biological	ADJ
bjp-19567	98	12	properties	property	NOUN
bjp-19567	98	13	including	include	VERB
bjp-19567	98	14	anticancerous	anticancerous	ADJ
bjp-19567	98	15	.	.	PUNCT
bjp-19567	99	1	for	for	ADP
bjp-19567	99	2	instance	instance	NOUN
bjp-19567	99	3	,	,	PUNCT
bjp-19567	99	4	intake	intake	NOUN
bjp-19567	99	5	of	of	ADP
bjp-19567	99	6	citrus	citrus	NOUN
bjp-19567	99	7	fruits	fruit	NOUN
bjp-19567	99	8	has	have	AUX
bjp-19567	99	9	been	be	AUX
bjp-19567	99	10	considered	consider	VERB
bjp-19567	99	11	not	not	PART
bjp-19567	99	12	only	only	ADV
bjp-19567	99	13	beneficial	beneficial	ADJ
bjp-19567	99	14	for	for	ADP
bjp-19567	99	15	health	health	NOUN
bjp-19567	99	16	but	but	CCONJ
bjp-19567	99	17	even	even	ADV
bjp-19567	99	18	possess	possess	VERB
bjp-19567	99	19	anti	anti	ADJ
bjp-19567	99	20	-	-	ADJ
bjp-19567	99	21	carcinogenic	carcinogenic	ADJ
bjp-19567	99	22	and	and	CCONJ
bjp-19567	99	23	anti	anti	ADJ
bjp-19567	99	24	-	-	ADJ
bjp-19567	99	25	tumor	tumor	ADJ
bjp-19567	99	26	activities	activity	NOUN
bjp-19567	99	27	(	(	PUNCT
bjp-19567	99	28	gullett	gullett	VERB
bjp-19567	99	29	et	et	NOUN
bjp-19567	99	30	al	al	PROPN
bjp-19567	99	31	.	.	PROPN
bjp-19567	99	32	,	,	PUNCT
bjp-19567	99	33	2010	2010	NUM
bjp-19567	99	34	;	;	PUNCT
bjp-19567	99	35	wu	wu	PROPN
bjp-19567	99	36	et	et	PROPN
bjp-19567	99	37	al	al	PROPN
bjp-19567	99	38	.	.	PROPN
bjp-19567	99	39	,	,	PUNCT
bjp-19567	99	40	2013	2013	NUM
bjp-19567	99	41	)	)	PUNCT
bjp-19567	99	42	.	.	PUNCT
bjp-19567	100	1	among	among	ADP
bjp-19567	100	2	numerous	numerous	ADJ
bjp-19567	100	3	active	active	ADJ
bjp-19567	100	4	flavonoids	flavonoid	NOUN
bjp-19567	100	5	in	in	ADP
bjp-19567	100	6	citrus	citrus	NOUN
bjp-19567	100	7	fruits	fruit	NOUN
bjp-19567	100	8	,	,	PUNCT
bjp-19567	100	9	nobiletin	nobiletin	NOUN
bjp-19567	100	10	has	have	AUX
bjp-19567	100	11	been	be	AUX
bjp-19567	100	12	reported	report	VERB
bjp-19567	100	13	to	to	PART
bjp-19567	100	14	possess	possess	VERB
bjp-19567	100	15	potent	potent	ADJ
bjp-19567	100	16	biological	biological	ADJ
bjp-19567	100	17	activities	activity	NOUN
bjp-19567	100	18	.	.	PUNCT
bjp-19567	101	1	previous	previous	ADJ
bjp-19567	101	2	studies	study	NOUN
bjp-19567	101	3	have	have	AUX
bjp-19567	101	4	described	describe	VERB
bjp-19567	101	5	various	various	ADJ
bjp-19567	101	6	biological	biological	ADJ
bjp-19567	101	7	effects	effect	NOUN
bjp-19567	101	8	of	of	ADP
bjp-19567	101	9	nobiletin	nobiletin	NOUN
bjp-19567	101	10	like	like	ADP
bjp-19567	101	11	anti	anti	ADJ
bjp-19567	101	12	-	-	ADJ
bjp-19567	101	13	inflammatory	inflammatory	ADJ
bjp-19567	101	14	,	,	PUNCT
bjp-19567	101	15	anti	anti	ADJ
bjp-19567	101	16	-	-	ADJ
bjp-19567	101	17	tumor	tumor	ADJ
bjp-19567	101	18	,	,	PUNCT
bjp-19567	101	19	anti	anti	ADJ
bjp-19567	101	20	-	-	ADJ
bjp-19567	101	21	metas	metas	ADJ
bjp-19567	101	22	-tasis	-tasis	NOUN
bjp-19567	101	23	and	and	CCONJ
bjp-19567	101	24	neuroprotective	neuroprotective	ADJ
bjp-19567	101	25	properties	property	NOUN
bjp-19567	101	26	(	(	PUNCT
bjp-19567	101	27	murakami	murakami	NOUN
bjp-19567	101	28	et	et	PROPN
bjp-19567	101	29	al	al	PROPN
bjp-19567	101	30	.	.	PROPN
bjp-19567	101	31	,	,	PUNCT
bjp-19567	101	32	2000	2000	NUM
bjp-19567	101	33	;	;	PUNCT
bjp-19567	101	34	nakajima	nakajima	PROPN
bjp-19567	101	35	et	et	PROPN
bjp-19567	101	36	al	al	PROPN
bjp-19567	101	37	.	.	PROPN
bjp-19567	101	38	,	,	PUNCT
bjp-19567	101	39	2007	2007	NUM
bjp-19567	101	40	;	;	PUNCT
bjp-19567	101	41	li	li	PROPN
bjp-19567	101	42	et	et	PROPN
bjp-19567	101	43	al	al	PROPN
bjp-19567	101	44	.	.	PROPN
bjp-19567	101	45	,	,	PUNCT
bjp-19567	101	46	2006	2006	NUM
bjp-19567	101	47	;	;	PUNCT
bjp-19567	101	48	shi	shi	PROPN
bjp-19567	101	49	et	et	PROPN
bjp-19567	101	50	al	al	PROPN
bjp-19567	101	51	.	.	PROPN
bjp-19567	101	52	,	,	PUNCT
bjp-19567	101	53	2013	2013	NUM
bjp-19567	101	54	)	)	PUNCT
bjp-19567	101	55	.	.	PUNCT
bjp-19567	102	1	recent	recent	ADJ
bjp-19567	102	2	studies	study	NOUN
bjp-19567	102	3	have	have	AUX
bjp-19567	102	4	also	also	ADV
bjp-19567	102	5	demonstrated	demonstrate	VERB
bjp-19567	102	6	compelling	compelling	ADJ
bjp-19567	102	7	role	role	NOUN
bjp-19567	102	8	of	of	ADP
bjp-19567	102	9	nobiletin	nobiletin	NOUN
bjp-19567	102	10	in	in	ADP
bjp-19567	102	11	initiating	initiate	VERB
bjp-19567	102	12	anti	anti	ADJ
bjp-19567	102	13	-	-	ADJ
bjp-19567	102	14	cancerous	cancerous	ADJ
bjp-19567	102	15	proper	proper	ADJ
bjp-19567	102	16	-ties	-tie	NOUN
bjp-19567	102	17	in	in	ADP
bjp-19567	102	18	various	various	ADJ
bjp-19567	102	19	cell	cell	NOUN
bjp-19567	102	20	culture	culture	NOUN
bjp-19567	102	21	systems	system	NOUN
bjp-19567	102	22	(	(	PUNCT
bjp-19567	102	23	luo	luo	PROPN
bjp-19567	102	24	et	et	PROPN
bjp-19567	102	25	al	al	PROPN
bjp-19567	102	26	.	.	PROPN
bjp-19567	102	27	,	,	PUNCT
bjp-19567	102	28	2009	2009	NUM
bjp-19567	102	29	;	;	PUNCT
bjp-19567	102	30	ishii	ishii	PROPN
bjp-19567	102	31	et	et	PROPN
bjp-19567	102	32	al	al	PROPN
bjp-19567	102	33	.	.	PROPN
bjp-19567	102	34	,	,	PUNCT
bjp-19567	102	35	2010	2010	NUM
bjp-19567	102	36	)	)	PUNCT
bjp-19567	102	37	.	.	PUNCT
bjp-19567	103	1	in	in	ADP
bjp-19567	103	2	order	order	NOUN
bjp-19567	103	3	to	to	PART
bjp-19567	103	4	observe	observe	VERB
bjp-19567	103	5	any	any	DET
bjp-19567	103	6	effect	effect	NOUN
bjp-19567	103	7	of	of	ADP
bjp-19567	103	8	nobiletin	nobiletin	NOUN
bjp-19567	103	9	on	on	ADP
bjp-19567	103	10	bone	bone	NOUN
bjp-19567	103	11	cancer	cancer	NOUN
bjp-19567	103	12	cells	cell	NOUN
bjp-19567	103	13	,	,	PUNCT
bjp-19567	103	14	mtt	mtt	NOUN
bjp-19567	103	15	and	and	CCONJ
bjp-19567	103	16	ldh	ldh	PROPN
bjp-19567	103	17	assay	assay	PROPN
bjp-19567	103	18	was	be	AUX
bjp-19567	103	19	performed	perform	VERB
bjp-19567	103	20	(	(	PUNCT
bjp-19567	103	21	figure	figure	NOUN
bjp-19567	103	22	2	2	NUM
bjp-19567	103	23	)	)	PUNCT
bjp-19567	103	24	.	.	PUNCT
bjp-19567	104	1	results	result	NOUN
bjp-19567	104	2	demonstrated	demonstrate	VERB
bjp-19567	104	3	dose	dose	NOUN
bjp-19567	104	4	-	-	PUNCT
bjp-19567	104	5	depen	depen	NOUN
bjp-19567	104	6	-dent	-dent	NOUN
bjp-19567	104	7	inhibitory	inhibitory	ADJ
bjp-19567	104	8	effect	effect	NOUN
bjp-19567	104	9	of	of	ADP
bjp-19567	104	10	nobiletin	nobiletin	NOUN
bjp-19567	104	11	on	on	ADP
bjp-19567	104	12	saos-2	saos-2	NUM
bjp-19567	104	13	after	after	ADP
bjp-19567	104	14	24	24	NUM
bjp-19567	104	15	,	,	PUNCT
bjp-19567	104	16	48	48	NUM
bjp-19567	104	17	and	and	CCONJ
bjp-19567	104	18	72	72	NUM
bjp-19567	104	19	hours	hour	NOUN
bjp-19567	104	20	treatment	treatment	NOUN
bjp-19567	104	21	of	of	ADP
bjp-19567	104	22	saos-2	saos-2	NUM
bjp-19567	104	23	cells	cell	NOUN
bjp-19567	104	24	with	with	ADP
bjp-19567	104	25	nobiletin	nobiletin	NOUN
bjp-19567	104	26	at	at	ADP
bjp-19567	104	27	various	various	ADJ
bjp-19567	104	28	doses	dose	NOUN
bjp-19567	104	29	of	of	ADP
bjp-19567	104	30	0.5	0.5	NUM
bjp-19567	104	31	,	,	PUNCT
bjp-19567	104	32	1.0	1.0	NUM
bjp-19567	104	33	,	,	PUNCT
bjp-19567	104	34	2.5	2.5	NUM
bjp-19567	104	35	,	,	PUNCT
bjp-19567	104	36	5.0	5.0	NUM
bjp-19567	104	37	and	and	CCONJ
bjp-19567	104	38	10.0	10.0	NUM
bjp-19567	104	39	µm	µm	NOUN
bjp-19567	104	40	.	.	PUNCT
bjp-19567	105	1	tumor	tumor	NOUN
bjp-19567	105	2	cells	cell	NOUN
bjp-19567	105	3	proliferation	proliferation	NOUN
bjp-19567	105	4	depends	depend	VERB
bjp-19567	105	5	on	on	ADP
bjp-19567	105	6	completed	complete	VERB
bjp-19567	105	7	cell	cell	NOUN
bjp-19567	105	8	cycles	cycle	NOUN
bjp-19567	105	9	(	(	PUNCT
bjp-19567	105	10	hartwell	hartwell	NOUN
bjp-19567	105	11	and	and	CCONJ
bjp-19567	105	12	kastan	kastan	PROPN
bjp-19567	105	13	,	,	PUNCT
bjp-19567	105	14	1994	1994	NUM
bjp-19567	105	15	)	)	PUNCT
bjp-19567	105	16	,	,	PUNCT
bjp-19567	105	17	regulated	regulate	VERB
bjp-19567	105	18	and	and	CCONJ
bjp-19567	105	19	controlled	control	VERB
bjp-19567	105	20	by	by	ADP
bjp-19567	105	21	g1	g1	PROPN
bjp-19567	105	22	/	/	SYM
bjp-19567	105	23	s	s	NOUN
bjp-19567	105	24	and	and	CCONJ
bjp-19567	105	25	g2	g2	PROPN
bjp-19567	105	26	/	/	SYM
bjp-19567	105	27	m	m	PROPN
bjp-19567	105	28	checkpoints	checkpoint	NOUN
bjp-19567	105	29	.	.	PUNCT
bjp-19567	106	1	these	these	DET
bjp-19567	106	2	checkpoints	checkpoint	NOUN
bjp-19567	106	3	are	be	AUX
bjp-19567	106	4	responsible	responsible	ADJ
bjp-19567	106	5	for	for	ADP
bjp-19567	106	6	triggering	trigger	VERB
bjp-19567	106	7	mitotic	mitotic	ADJ
bjp-19567	106	8	spindle	spindle	NOUN
bjp-19567	106	9	assembly	assembly	NOUN
bjp-19567	106	10	formation	formation	NOUN
bjp-19567	106	11	and	and	CCONJ
bjp-19567	106	12	ensure	ensure	VERB
bjp-19567	106	13	that	that	SCONJ
bjp-19567	106	14	other	other	ADJ
bjp-19567	106	15	downstream	downstream	ADJ
bjp-19567	106	16	activities	activity	NOUN
bjp-19567	106	17	are	be	AUX
bjp-19567	106	18	commenced	commence	VERB
bjp-19567	106	19	only	only	ADV
bjp-19567	106	20	when	when	SCONJ
bjp-19567	106	21	upstream	upstream	ADJ
bjp-19567	106	22	activities	activity	NOUN
bjp-19567	106	23	are	be	AUX
bjp-19567	106	24	correctly	correctly	ADV
bjp-19567	106	25	completed	complete	VERB
bjp-19567	106	26	(	(	PUNCT
bjp-19567	106	27	hartwell	hartwell	NOUN
bjp-19567	106	28	and	and	CCONJ
bjp-19567	106	29	weinert	weinert	ADJ
bjp-19567	106	30	,	,	PUNCT
bjp-19567	106	31	1989	1989	NUM
bjp-19567	106	32	)	)	PUNCT
bjp-19567	106	33	.	.	PUNCT
bjp-19567	107	1	regulation	regulation	NOUN
bjp-19567	107	2	of	of	ADP
bjp-19567	107	3	cell	cell	NOUN
bjp-19567	107	4	cycle	cycle	NOUN
bjp-19567	107	5	checkpoint	checkpoint	NOUN
bjp-19567	107	6	also	also	ADV
bjp-19567	107	7	eliminates	eliminate	VERB
bjp-19567	107	8	impaired	impaired	ADJ
bjp-19567	107	9	cells	cell	NOUN
bjp-19567	107	10	either	either	CCONJ
bjp-19567	107	11	by	by	ADP
bjp-19567	107	12	inducing	induce	VERB
bjp-19567	107	13	apoptosis	apoptosis	NOUN
bjp-19567	107	14	or	or	CCONJ
bjp-19567	107	15	blocking	block	VERB
bjp-19567	107	16	cell	cell	NOUN
bjp-19567	107	17	cycle	cycle	NOUN
bjp-19567	107	18	progression	progression	NOUN
bjp-19567	107	19	(	(	PUNCT
bjp-19567	107	20	causing	cause	VERB
bjp-19567	107	21	apoptosis	apoptosis	NOUN
bjp-19567	107	22	)	)	PUNCT
bjp-19567	107	23	.	.	PUNCT
bjp-19567	108	1	nobiletin	nobiletin	PROPN
bjp-19567	108	2	has	have	AUX
bjp-19567	108	3	been	be	AUX
bjp-19567	108	4	demonstrated	demonstrate	VERB
bjp-19567	108	5	to	to	PART
bjp-19567	108	6	possess	possess	VERB
bjp-19567	108	7	anti	anti	ADJ
bjp-19567	108	8	-	-	ADJ
bjp-19567	108	9	proliferative	proliferative	ADJ
bjp-19567	108	10	properties	property	NOUN
bjp-19567	108	11	by	by	ADP
bjp-19567	108	12	promoting	promote	VERB
bjp-19567	108	13	apoptosis	apoptosis	NOUN
bjp-19567	108	14	and	and	CCONJ
bjp-19567	108	15	cell	cell	NOUN
bjp-19567	108	16	cycle	cycle	NOUN
bjp-19567	108	17	arrest	arrest	NOUN
bjp-19567	108	18	(	(	PUNCT
bjp-19567	108	19	luo	luo	PROPN
bjp-19567	108	20	et	et	PROPN
bjp-19567	108	21	al	al	PROPN
bjp-19567	108	22	.	.	PROPN
bjp-19567	108	23	,	,	PUNCT
bjp-19567	108	24	2008	2008	NUM
bjp-19567	108	25	,	,	PUNCT
bjp-19567	108	26	luo	luo	PROPN
bjp-19567	108	27	et	et	PROPN
bjp-19567	108	28	al	al	PROPN
bjp-19567	108	29	.	.	PROPN
bjp-19567	108	30	,	,	PUNCT
bjp-19567	108	31	2009	2009	NUM
bjp-19567	108	32	;	;	PUNCT
bjp-19567	108	33	ishii	ishii	PROPN
bjp-19567	108	34	et	et	PROPN
bjp-19567	108	35	al	al	PROPN
bjp-19567	108	36	.	.	PROPN
bjp-19567	108	37	,	,	PUNCT
bjp-19567	108	38	2010	2010	NUM
bjp-19567	108	39	)	)	PUNCT
bjp-19567	108	40	.	.	PUNCT
bjp-19567	109	1	thus	thus	ADV
bjp-19567	109	2	,	,	PUNCT
bjp-19567	109	3	to	to	PART
bjp-19567	109	4	confirm	confirm	VERB
bjp-19567	109	5	the	the	DET
bjp-19567	109	6	effect	effect	NOUN
bjp-19567	109	7	of	of	ADP
bjp-19567	109	8	nobiletin	nobiletin	NOUN
bjp-19567	109	9	on	on	ADP
bjp-19567	109	10	apoptosis	apoptosis	NOUN
bjp-19567	109	11	and	and	CCONJ
bjp-19567	109	12	cell	cell	NOUN
bjp-19567	109	13	proliferation	proliferation	NOUN
bjp-19567	109	14	of	of	ADP
bjp-19567	109	15	saos-2	saos-2	NUM
bjp-19567	109	16	cells	cell	NOUN
bjp-19567	109	17	flow	flow	VERB
bjp-19567	109	18	cytometry	cytometry	NOUN
bjp-19567	109	19	was	be	AUX
bjp-19567	109	20	performed	perform	VERB
bjp-19567	109	21	.	.	PUNCT
bjp-19567	110	1	the	the	DET
bjp-19567	110	2	results	result	NOUN
bjp-19567	110	3	showed	show	VERB
bjp-19567	110	4	increased	increase	VERB
bjp-19567	110	5	rate	rate	NOUN
bjp-19567	110	6	of	of	ADP
bjp-19567	110	7	apoptosis	apoptosis	NOUN
bjp-19567	110	8	in	in	ADP
bjp-19567	110	9	a	a	DET
bjp-19567	110	10	dose	dose	NOUN
bjp-19567	110	11	-	-	PUNCT
bjp-19567	110	12	dependent	dependent	ADJ
bjp-19567	110	13	manner	manner	NOUN
bjp-19567	110	14	with	with	ADP
bjp-19567	110	15	increase	increase	NOUN
bjp-19567	110	16	in	in	ADP
bjp-19567	110	17	cell	cell	NOUN
bjp-19567	110	18	number	number	NOUN
bjp-19567	110	19	arrested	arrest	VERB
bjp-19567	110	20	in	in	ADP
bjp-19567	110	21	g2	g2	PROPN
bjp-19567	110	22	/	/	SYM
bjp-19567	110	23	m	m	PROPN
bjp-19567	110	24	phase	phase	NOUN
bjp-19567	110	25	of	of	ADP
bjp-19567	110	26	cell	cell	NOUN
bjp-19567	110	27	cycle	cycle	NOUN
bjp-19567	110	28	.	.	PUNCT
bjp-19567	111	1	taken	take	VERB
bjp-19567	111	2	together	together	ADV
bjp-19567	111	3	,	,	PUNCT
bjp-19567	111	4	results	result	NOUN
bjp-19567	111	5	demonstrated	demonstrate	VERB
bjp-19567	111	6	that	that	SCONJ
bjp-19567	111	7	nobiletin	nobiletin	NOUN
bjp-19567	111	8	induces	induce	VERB
bjp-19567	111	9	anti	anti	ADJ
bjp-19567	111	10	-	-	ADJ
bjp-19567	111	11	proliferative	proliferative	ADJ
bjp-19567	111	12	effect	effect	NOUN
bjp-19567	111	13	on	on	ADP
bjp-19567	111	14	osteosarcoma	osteosarcoma	ADJ
bjp-19567	111	15	cells	cell	NOUN
bjp-19567	111	16	,	,	PUNCT
bjp-19567	111	17	saos-2	saos-2	NUM
bjp-19567	111	18	,	,	PUNCT
bjp-19567	111	19	by	by	ADP
bjp-19567	111	20	inducing	induce	VERB
bjp-19567	111	21	cell	cell	NOUN
bjp-19567	111	22	cycle	cycle	NOUN
bjp-19567	111	23	arrest	arrest	NOUN
bjp-19567	111	24	and	and	CCONJ
bjp-19567	111	25	apoptosis	apoptosis	NOUN
bjp-19567	111	26	,	,	PUNCT
bjp-19567	111	27	similar	similar	ADJ
bjp-19567	111	28	to	to	ADP
bjp-19567	111	29	reported	report	VERB
bjp-19567	111	30	effect	effect	NOUN
bjp-19567	111	31	in	in	ADP
bjp-19567	111	32	hepatocellular	hepatocellular	ADJ
bjp-19567	111	33	carcinoma	carcinoma	NOUN
bjp-19567	111	34	cells	cell	NOUN
bjp-19567	111	35	(	(	PUNCT
bjp-19567	111	36	ma	ma	PROPN
bjp-19567	111	37	et	et	PROPN
bjp-19567	111	38	al	al	PROPN
bjp-19567	111	39	.	.	PROPN
bjp-19567	111	40	,	,	PUNCT
bjp-19567	111	41	2014	2014	NUM
bjp-19567	111	42	)	)	PUNCT
bjp-19567	111	43	.	.	PUNCT
bjp-19567	112	1	two	two	NUM
bjp-19567	112	2	major	major	ADJ
bjp-19567	112	3	signaling	signal	VERB
bjp-19567	112	4	pathways	pathway	NOUN
bjp-19567	112	5	that	that	PRON
bjp-19567	112	6	are	be	AUX
bjp-19567	112	7	involved	involve	VERB
bjp-19567	112	8	in	in	ADP
bjp-19567	112	9	apoptotic	apoptotic	ADJ
bjp-19567	112	10	cell	cell	NOUN
bjp-19567	112	11	deathare	deathare	VERB
bjp-19567	112	12	intrinsic	intrinsic	ADJ
bjp-19567	112	13	pathway	pathway	NOUN
bjp-19567	112	14	(	(	PUNCT
bjp-19567	112	15	mitochondria	mitochondria	PROPN
bjp-19567	112	16	pathway	pathway	NOUN
bjp-19567	112	17	)	)	PUNCT
bjp-19567	112	18	or	or	CCONJ
bjp-19567	112	19	extrinsic	extrinsic	ADJ
bjp-19567	112	20	pathways	pathway	NOUN
bjp-19567	112	21	(	(	PUNCT
bjp-19567	112	22	death	death	NOUN
bjp-19567	112	23	receptor	receptor	NOUN
bjp-19567	112	24	pathway	pathway	NOUN
bjp-19567	112	25	)	)	PUNCT
bjp-19567	113	1	(	(	PUNCT
bjp-19567	113	2	kroemer	kroemer	PROPN
bjp-19567	113	3	et	et	PROPN
bjp-19567	113	4	al	al	PROPN
bjp-19567	113	5	.	.	PROPN
bjp-19567	113	6	,	,	PUNCT
bjp-19567	113	7	2007	2007	NUM
bjp-19567	113	8	;	;	PUNCT
bjp-19567	113	9	lai	lai	PROPN
bjp-19567	113	10	et	et	PROPN
bjp-19567	113	11	al	al	PROPN
bjp-19567	113	12	.	.	PROPN
bjp-19567	113	13	,	,	PUNCT
bjp-19567	113	14	2007	2007	NUM
bjp-19567	113	15	)	)	PUNCT
bjp-19567	113	16	.	.	PUNCT
bjp-19567	114	1	the	the	DET
bjp-19567	114	2	intrinsic	intrinsic	ADJ
bjp-19567	114	3	pathway	pathway	NOUN
bjp-19567	114	4	directs	direct	VERB
bjp-19567	114	5	death	death	NOUN
bjp-19567	114	6	signals	signal	NOUN
bjp-19567	114	7	to	to	PART
bjp-19567	114	8	mitochondria	mitochondria	VERB
bjp-19567	114	9	by	by	ADP
bjp-19567	114	10	releasing	release	VERB
bjp-19567	114	11	mitochondrial	mitochondrial	ADJ
bjp-19567	114	12	inter	inter	ADJ
bjp-19567	114	13	-	-	ADJ
bjp-19567	114	14	membrane	membrane	ADJ
bjp-19567	114	15	proteins	protein	NOUN
bjp-19567	114	16	such	such	ADJ
bjp-19567	114	17	as	as	ADP
bjp-19567	114	18	cytochrome	cytochrome	PROPN
bjp-19567	114	19	c.	c.	NOUN
bjp-19567	114	20	released	release	VERB
bjp-19567	114	21	cytochrome	cytochrome	NOUN
bjp-19567	114	22	c	c	NOUN
bjp-19567	114	23	in	in	ADP
bjp-19567	114	24	turn	turn	NOUN
bjp-19567	114	25	associates	associate	NOUN
bjp-19567	114	26	with	with	ADP
bjp-19567	114	27	apoptotic	apoptotic	ADJ
bjp-19567	114	28	protease	protease	NOUN
bjp-19567	114	29	-	-	PUNCT
bjp-19567	114	30	activating	activate	VERB
bjp-19567	114	31	factor‑1	factor‑1	PROPN
bjp-19567	114	32	(	(	PUNCT
bjp-19567	114	33	apaf-1	apaf-1	NUM
bjp-19567	114	34	)	)	PUNCT
bjp-19567	114	35	and	and	CCONJ
bjp-19567	114	36	pro	pro	ADJ
bjp-19567	114	37	-	-	ADJ
bjp-19567	114	38	caspase-9	caspase-9	ADJ
bjp-19567	114	39	to	to	PART
bjp-19567	114	40	form	form	VERB
bjp-19567	114	41	the	the	DET
bjp-19567	114	42	apoptosome	apoptosome	NOUN
bjp-19567	114	43	,	,	PUNCT
bjp-19567	114	44	leading	lead	VERB
bjp-19567	114	45	to	to	ADP
bjp-19567	114	46	the	the	DET
bjp-19567	114	47	activation	activation	NOUN
bjp-19567	114	48	of	of	ADP
bjp-19567	114	49	caspase-3	caspase-3	PROPN
bjp-19567	114	50	.	.	PUNCT
bjp-19567	115	1	on	on	ADP
bjp-19567	115	2	the	the	DET
bjp-19567	115	3	other	other	ADJ
bjp-19567	115	4	hand	hand	NOUN
bjp-19567	115	5	,	,	PUNCT
bjp-19567	115	6	extrinsic	extrinsic	ADJ
bjp-19567	115	7	pathway	pathway	NOUN
bjp-19567	115	8	acts	act	VERB
bjp-19567	115	9	through	through	ADP
bjp-19567	115	10	the	the	DET
bjp-19567	115	11	activation	activation	NOUN
bjp-19567	115	12	of	of	ADP
bjp-19567	115	13	the	the	DET
bjp-19567	115	14	cell	cell	NOUN
bjp-19567	115	15	surface	surface	NOUN
bjp-19567	115	16	410	410	NUM
bjp-19567	115	17	bangladesh	bangladesh	PROPN
bjp-19567	115	18	j	j	PROPN
bjp-19567	115	19	pharmacol	pharmacol	PROPN
bjp-19567	115	20	2014	2014	NUM
bjp-19567	115	21	;	;	PUNCT
bjp-19567	115	22	9	9	NUM
bjp-19567	115	23	:	:	SYM
bjp-19567	115	24	406	406	NUM
bjp-19567	115	25	-	-	SYM
bjp-19567	115	26	412	412	NUM
bjp-19567	115	27	b	b	NOUN
bjp-19567	115	28	c	c	NOUN
bjp-19567	115	29	figure	figure	NOUN
bjp-19567	115	30	5	5	NUM
bjp-19567	115	31	:	:	PUNCT
bjp-19567	115	32	anti	anti	ADJ
bjp-19567	115	33	-	-	ADJ
bjp-19567	115	34	proliferative	proliferative	ADJ
bjp-19567	115	35	effect	effect	NOUN
bjp-19567	115	36	of	of	ADP
bjp-19567	115	37	nobiletin	nobiletin	NOUN
bjp-19567	115	38	(	(	PUNCT
bjp-19567	115	39	5	5	NUM
bjp-19567	115	40	μm	μm	NUM
bjp-19567	115	41	)	)	PUNCT
bjp-19567	115	42	on	on	ADP
bjp-19567	115	43	saos-2	saos-2	NUM
bjp-19567	115	44	cells	cell	NOUN
bjp-19567	115	45	after	after	ADP
bjp-19567	115	46	24	24	NUM
bjp-19567	115	47	hours	hour	NOUN
bjp-19567	115	48	of	of	ADP
bjp-19567	115	49	treatment	treatment	NOUN
bjp-19567	115	50	(	(	PUNCT
bjp-19567	115	51	a	a	NOUN
bjp-19567	115	52	)	)	PUNCT
bjp-19567	115	53	after	after	ADP
bjp-19567	115	54	blocking	block	VERB
bjp-19567	115	55	erk	erk	NOUN
bjp-19567	115	56	signaling	signal	VERB
bjp-19567	115	57	pathways	pathway	NOUN
bjp-19567	115	58	by	by	ADP
bjp-19567	115	59	pd98059	pd98059	NOUN
bjp-19567	115	60	(	(	PUNCT
bjp-19567	115	61	b	b	NOUN
bjp-19567	115	62	)	)	PUNCT
bjp-19567	115	63	after	after	ADP
bjp-19567	115	64	transfecting	transfecte	VERB
bjp-19567	115	65	saos-2	saos-2	NUM
bjp-19567	115	66	cells	cell	NOUN
bjp-19567	115	67	by	by	ADP
bjp-19567	115	68	myraktdeltaph	myraktdeltaph	NOUN
bjp-19567	115	69	plasmid	plasmid	ADJ
bjp-19567	115	70	dna	dna	NOUN
bjp-19567	115	71	.	.	PUNCT
bjp-19567	116	1	three	three	NUM
bjp-19567	116	2	independent	independent	ADJ
bjp-19567	116	3	experiments	experiment	NOUN
bjp-19567	116	4	were	be	AUX
bjp-19567	116	5	performed	perform	VERB
bjp-19567	116	6	and	and	CCONJ
bjp-19567	116	7	data	datum	NOUN
bjp-19567	116	8	is	be	AUX
bjp-19567	116	9	expressed	express	VERB
bjp-19567	116	10	as	as	ADP
bjp-19567	116	11	their	their	PRON
bjp-19567	116	12	mean	mean	ADJ
bjp-19567	116	13	±	±	NUM
bjp-19567	116	14	sd	sd	NOUN
bjp-19567	116	15	(	(	PUNCT
bjp-19567	116	16	ap<0.05	ap<0.05	NOUN
bjp-19567	116	17	,	,	PUNCT
bjp-19567	116	18	bp<0.01	bp<0.01	NOUN
bjp-19567	116	19	,	,	PUNCT
bjp-19567	116	20	cp<0.001	cp<0.001	NOUN
bjp-19567	116	21	)	)	PUNCT
bjp-19567	116	22	b	b	NOUN
bjp-19567	117	1	ca	ca	NOUN
bjp-19567	117	2	b	b	PROPN
bjp-19567	117	3	pakt	pakt	PROPN
bjp-19567	117	4	akt	akt	PROPN
bjp-19567	117	5	perk	perk	PROPN
bjp-19567	117	6	erk	erk	PROPN
bjp-19567	117	7	-actin	-actin	PROPN
bjp-19567	117	8	0	0	NUM
bjp-19567	117	9	1.0	1.0	NUM
bjp-19567	117	10	2.5	2.5	NUM
bjp-19567	117	11	5.0	5.0	NUM
bjp-19567	117	12	10	10	NUM
bjp-19567	117	13	µm	µm	NUM
bjp-19567	117	14	figure	figure	NOUN
bjp-19567	117	15	4	4	NUM
bjp-19567	117	16	:	:	PUNCT
bjp-19567	117	17	nobiletin	nobiletin	ADJ
bjp-19567	117	18	regulated	regulated	ADJ
bjp-19567	117	19	expression	expression	NOUN
bjp-19567	117	20	of	of	ADP
bjp-19567	117	21	pakt	pakt	NOUN
bjp-19567	117	22	,	,	PUNCT
bjp-19567	117	23	akt	akt	PROPN
bjp-19567	117	24	,	,	PUNCT
bjp-19567	117	25	perk	perk	PROPN
bjp-19567	117	26	,	,	PUNCT
bjp-19567	117	27	erk	erk	NOUN
bjp-19567	117	28	and	and	CCONJ
bjp-19567	117	29	-actin	-actin	NOUN
bjp-19567	117	30	in	in	ADP
bjp-19567	117	31	saos-2	saos-2	NUM
bjp-19567	117	32	cells	cell	NOUN
bjp-19567	117	33	receptors	receptor	NOUN
bjp-19567	117	34	through	through	ADP
bjp-19567	117	35	fas	fas	ADJ
bjp-19567	117	36	/	/	SYM
bjp-19567	117	37	fas	fas	PROPN
bjp-19567	117	38	ligand	ligand	PROPN
bjp-19567	117	39	(	(	PUNCT
bjp-19567	117	40	fasl	fasl	PROPN
bjp-19567	117	41	)	)	PUNCT
bjp-19567	117	42	or	or	CCONJ
bjp-19567	117	43	tnf	tnf	PROPN
bjp-19567	117	44	-	-	PUNCT
bjp-19567	117	45	related	relate	VERB
bjp-19567	117	46	apoptosis	apoptosis	NOUN
bjp-19567	117	47	-	-	PUNCT
bjp-19567	117	48	inducing	induce	VERB
bjp-19567	117	49	ligand	ligand	NOUN
bjp-19567	117	50	(	(	PUNCT
bjp-19567	117	51	trail	trail	NOUN
bjp-19567	117	52	)	)	PUNCT
bjp-19567	117	53	to	to	PART
bjp-19567	117	54	promote	promote	VERB
bjp-19567	117	55	caspase8	caspase8	NOUN
bjp-19567	117	56	activation	activation	NOUN
bjp-19567	117	57	.	.	PUNCT
bjp-19567	118	1	another	another	DET
bjp-19567	118	2	signaling	signal	VERB
bjp-19567	118	3	pathway	pathway	NOUN
bjp-19567	118	4	independent	independent	ADJ
bjp-19567	118	5	of	of	ADP
bjp-19567	118	6	caspase	caspase	PROPN
bjp-19567	118	7	pathway	pathway	NOUN
bjp-19567	118	8	also	also	ADV
bjp-19567	118	9	exists	exist	VERB
bjp-19567	118	10	which	which	PRON
bjp-19567	118	11	leads	lead	VERB
bjp-19567	118	12	to	to	ADP
bjp-19567	118	13	cell	cell	NOUN
bjp-19567	118	14	death	death	NOUN
bjp-19567	118	15	by	by	ADP
bjp-19567	118	16	releasing	release	VERB
bjp-19567	118	17	apoptosis	apoptosis	NOUN
bjp-19567	118	18	inducing	induce	VERB
bjp-19567	118	19	factor	factor	NOUN
bjp-19567	118	20	(	(	PUNCT
bjp-19567	118	21	aif	aif	PROPN
bjp-19567	118	22	)	)	PUNCT
bjp-19567	118	23	or	or	CCONJ
bjp-19567	118	24	endonuclease	endonuclease	NOUN
bjp-19567	118	25	g	g	PROPN
bjp-19567	118	26	(	(	PUNCT
bjp-19567	118	27	endo	endo	NOUN
bjp-19567	118	28	g	g	NOUN
bjp-19567	118	29	)	)	PUNCT
bjp-19567	118	30	from	from	ADP
bjp-19567	118	31	mitochondria	mitochondria	PROPN
bjp-19567	118	32	(	(	PUNCT
bjp-19567	118	33	park	park	NOUN
bjp-19567	118	34	,	,	PUNCT
bjp-19567	118	35	2012	2012	NUM
bjp-19567	118	36	)	)	PUNCT
bjp-19567	118	37	.	.	PUNCT
bjp-19567	119	1	thus	thus	ADV
bjp-19567	119	2	,	,	PUNCT
bjp-19567	119	3	to	to	PART
bjp-19567	119	4	determine	determine	VERB
bjp-19567	119	5	whether	whether	SCONJ
bjp-19567	119	6	nobiletin	nobiletin	NOUN
bjp-19567	119	7	involves	involve	VERB
bjp-19567	119	8	any	any	PRON
bjp-19567	119	9	of	of	ADP
bjp-19567	119	10	these	these	DET
bjp-19567	119	11	pathways	pathway	NOUN
bjp-19567	119	12	in	in	ADP
bjp-19567	119	13	inducing	induce	VERB
bjp-19567	119	14	apoptosis	apoptosis	NOUN
bjp-19567	119	15	in	in	ADP
bjp-19567	119	16	saos-2	saos-2	NUM
bjp-19567	119	17	cells	cell	NOUN
bjp-19567	119	18	,	,	PUNCT
bjp-19567	119	19	we	we	PRON
bjp-19567	119	20	first	first	ADV
bjp-19567	119	21	examined	examine	VERB
bjp-19567	119	22	the	the	DET
bjp-19567	119	23	possibility	possibility	NOUN
bjp-19567	119	24	of	of	ADP
bjp-19567	119	25	activation	activation	NOUN
bjp-19567	119	26	of	of	ADP
bjp-19567	119	27	intrinsic	intrinsic	ADJ
bjp-19567	119	28	pathway	pathway	NOUN
bjp-19567	119	29	by	by	ADP
bjp-19567	119	30	measuring	measure	VERB
bjp-19567	119	31	the	the	DET
bjp-19567	119	32	activity	activity	NOUN
bjp-19567	119	33	of	of	ADP
bjp-19567	119	34	caspase-9	caspase-9	PROPN
bjp-19567	119	35	and	and	CCONJ
bjp-19567	119	36	-3	-3	PUNCT
bjp-19567	119	37	in	in	ADP
bjp-19567	119	38	saos-2	saos-2	NUM
bjp-19567	119	39	cells	cell	NOUN
bjp-19567	119	40	.	.	PUNCT
bjp-19567	120	1	results	result	NOUN
bjp-19567	120	2	showed	show	VERB
bjp-19567	120	3	increase	increase	NOUN
bjp-19567	120	4	in	in	ADP
bjp-19567	120	5	caspase-9	caspase-9	PROPN
bjp-19567	120	6	and	and	CCONJ
bjp-19567	120	7	-3	-3	PUNCT
bjp-19567	120	8	activity	activity	NOUN
bjp-19567	120	9	indicating	indicate	VERB
bjp-19567	120	10	the	the	DET
bjp-19567	120	11	role	role	NOUN
bjp-19567	120	12	of	of	ADP
bjp-19567	120	13	intrinsic	intrinsic	ADJ
bjp-19567	120	14	pathways	pathway	NOUN
bjp-19567	120	15	in	in	ADP
bjp-19567	120	16	inducing	induce	VERB
bjp-19567	120	17	apoptosis	apoptosis	NOUN
bjp-19567	120	18	in	in	ADP
bjp-19567	120	19	saos-2	saos-2	NUM
bjp-19567	120	20	cells	cell	NOUN
bjp-19567	120	21	.	.	PUNCT
bjp-19567	121	1	it	it	PRON
bjp-19567	121	2	is	be	AUX
bjp-19567	121	3	well	well	ADV
bjp-19567	121	4	documented	document	VERB
bjp-19567	121	5	that	that	SCONJ
bjp-19567	121	6	the	the	DET
bjp-19567	121	7	activation	activation	NOUN
bjp-19567	121	8	of	of	ADP
bjp-19567	121	9	mitogenactivated	mitogenactivated	ADJ
bjp-19567	121	10	protein	protein	NOUN
bjp-19567	121	11	(	(	PUNCT
bjp-19567	121	12	map)/extracellular	map)/extracellular	ADJ
bjp-19567	121	13	signal	signal	NOUN
bjp-19567	121	14	-	-	PUNCT
bjp-19567	121	15	regulated	regulate	VERB
bjp-19567	121	16	kinase	kinase	NOUN
bjp-19567	121	17	(	(	PUNCT
bjp-19567	121	18	mek	mek	PROPN
bjp-19567	121	19	)	)	PUNCT
bjp-19567	121	20	is	be	AUX
bjp-19567	121	21	associated	associate	VERB
bjp-19567	121	22	with	with	ADP
bjp-19567	121	23	anti	anti	ADJ
bjp-19567	121	24	-	-	ADJ
bjp-19567	121	25	tumor	tumor	ADJ
bjp-19567	121	26	activities	activity	NOUN
bjp-19567	121	27	.	.	PUNCT
bjp-19567	122	1	in	in	ADP
bjp-19567	122	2	addition	addition	NOUN
bjp-19567	122	3	,	,	PUNCT
bjp-19567	122	4	studies	study	NOUN
bjp-19567	122	5	have	have	AUX
bjp-19567	122	6	shown	show	VERB
bjp-19567	122	7	that	that	PRON
bjp-19567	122	8	erk	erk	PROPN
bjp-19567	122	9	/	/	SYM
bjp-19567	122	10	mapk	mapk	NOUN
bjp-19567	122	11	can	can	AUX
bjp-19567	122	12	positively	positively	ADV
bjp-19567	122	13	mediate	mediate	VERB
bjp-19567	122	14	phosphorylation	phosphorylation	NOUN
bjp-19567	122	15	of	of	ADP
bjp-19567	122	16	bcl-2	bcl-2	NOUN
bjp-19567	122	17	at	at	ADP
bjp-19567	122	18	ser-70	ser-70	PROPN
bjp-19567	122	19	,	,	PUNCT
bjp-19567	122	20	causing	cause	VERB
bjp-19567	122	21	anti	anti	ADJ
bjp-19567	122	22	-	-	ADJ
bjp-19567	122	23	apoptotic	apoptotic	ADJ
bjp-19567	122	24	function	function	NOUN
bjp-19567	122	25	to	to	ADP
bjp-19567	122	26	down	down	ADV
bjp-19567	122	27	-	-	PUNCT
bjp-19567	122	28	regulate	regulate	VERB
bjp-19567	122	29	bcl-2	bcl-2	ADJ
bjp-19567	122	30	expression	expression	NOUN
bjp-19567	122	31	.	.	PUNCT
bjp-19567	123	1	activation	activation	NOUN
bjp-19567	123	2	of	of	ADP
bjp-19567	123	3	phosphatidyl	phosphatidyl	ADJ
bjp-19567	123	4	inositol	inositol	NOUN
bjp-19567	123	5	3	3	NUM
bjp-19567	123	6	-	-	PUNCT
bjp-19567	123	7	kinase	kinase	NOUN
bjp-19567	123	8	(	(	PUNCT
bjp-19567	123	9	pi3k	pi3k	NOUN
bjp-19567	123	10	)	)	PUNCT
bjp-19567	123	11	leads	lead	VERB
bjp-19567	123	12	to	to	ADP
bjp-19567	123	13	phosphorylation	phosphorylation	NOUN
bjp-19567	123	14	of	of	ADP
bjp-19567	123	15	phosphatidyl	phosphatidyl	NOUN
bjp-19567	123	16	inositides	inositide	NOUN
bjp-19567	123	17	,	,	PUNCT
bjp-19567	123	18	which	which	PRON
bjp-19567	123	19	in	in	ADP
bjp-19567	123	20	turn	turn	NOUN
bjp-19567	123	21	activates	activate	VERB
bjp-19567	123	22	the	the	DET
bjp-19567	123	23	down	down	ADJ
bjp-19567	123	24	-	-	PUNCT
bjp-19567	123	25	stream	stream	NOUN
bjp-19567	123	26	main	main	ADJ
bjp-19567	123	27	target	target	NOUN
bjp-19567	123	28	,	,	PUNCT
bjp-19567	123	29	akt	akt	PROPN
bjp-19567	123	30	,	,	PUNCT
bjp-19567	123	31	known	know	VERB
bjp-19567	123	32	to	to	PART
bjp-19567	123	33	play	play	VERB
bjp-19567	123	34	various	various	ADJ
bjp-19567	123	35	imperative	imperative	ADJ
bjp-19567	123	36	roles	role	NOUN
bjp-19567	123	37	in	in	ADP
bjp-19567	123	38	regulating	regulate	VERB
bjp-19567	123	39	cellular	cellular	ADJ
bjp-19567	123	40	growth	growth	NOUN
bjp-19567	123	41	,	,	PUNCT
bjp-19567	123	42	adhesion	adhesion	NOUN
bjp-19567	123	43	,	,	PUNCT
bjp-19567	123	44	differentiation	differentiation	NOUN
bjp-19567	123	45	and	and	CCONJ
bjp-19567	123	46	the	the	DET
bjp-19567	123	47	inflammatory	inflammatory	ADJ
bjp-19567	123	48	reaction	reaction	NOUN
bjp-19567	123	49	.	.	PUNCT
bjp-19567	124	1	nobiletin	nobiletin	NOUN
bjp-19567	124	2	has	have	AUX
bjp-19567	124	3	been	be	AUX
bjp-19567	124	4	reported	report	VERB
bjp-19567	124	5	to	to	PART
bjp-19567	124	6	mediate	mediate	VERB
bjp-19567	124	7	inhibition	inhibition	NOUN
bjp-19567	124	8	of	of	ADP
bjp-19567	124	9	tumor	tumor	NOUN
bjp-19567	124	10	promotion	promotion	NOUN
bjp-19567	124	11	through	through	ADP
bjp-19567	124	12	regulation	regulation	NOUN
bjp-19567	124	13	of	of	ADP
bjp-19567	124	14	mapk	mapk	PROPN
bjp-19567	124	15	/	/	SYM
bjp-19567	124	16	erk	erk	PROPN
bjp-19567	124	17	and	and	CCONJ
bjp-19567	124	18	akt	akt	PROPN
bjp-19567	124	19	protein	protein	NOUN
bjp-19567	124	20	kinase	kinase	PROPN
bjp-19567	124	21	cascades	cascade	NOUN
bjp-19567	124	22	(	(	PUNCT
bjp-19567	124	23	shi	shi	PROPN
bjp-19567	124	24	et	et	PROPN
bjp-19567	124	25	al	al	PROPN
bjp-19567	124	26	.	.	PROPN
bjp-19567	124	27	,	,	PUNCT
bjp-19567	124	28	2013	2013	NUM
bjp-19567	124	29	,	,	PUNCT
bjp-19567	124	30	aoki	aoki	PROPN
bjp-19567	124	31	et	et	PROPN
bjp-19567	124	32	al	al	PROPN
bjp-19567	124	33	.	.	PROPN
bjp-19567	124	34	,	,	PUNCT
bjp-19567	124	35	2013	2013	NUM
bjp-19567	124	36	;	;	PUNCT
bjp-19567	124	37	chen	chen	PROPN
bjp-19567	124	38	et	et	PROPN
bjp-19567	124	39	al	al	PROPN
bjp-19567	124	40	.	.	PROPN
bjp-19567	124	41	,	,	PUNCT
bjp-19567	124	42	2014	2014	NUM
bjp-19567	124	43	;	;	PUNCT
bjp-19567	124	44	lai	lai	PROPN
bjp-19567	124	45	et	et	PROPN
bjp-19567	124	46	al	al	PROPN
bjp-19567	124	47	.	.	PROPN
bjp-19567	124	48	,	,	PUNCT
bjp-19567	124	49	2008	2008	NUM
bjp-19567	124	50	)	)	PUNCT
bjp-19567	124	51	.	.	PUNCT
bjp-19567	125	1	consequently	consequently	ADV
bjp-19567	125	2	,	,	PUNCT
bjp-19567	125	3	to	to	PART
bjp-19567	125	4	elucidate	elucidate	VERB
bjp-19567	125	5	whether	whether	SCONJ
bjp-19567	125	6	nobiletin	nobiletin	ADJ
bjp-19567	125	7	influences	influence	NOUN
bjp-19567	125	8	intrinsic	intrinsic	ADJ
bjp-19567	125	9	apoptotic	apoptotic	ADJ
bjp-19567	125	10	signaling	signal	VERB
bjp-19567	125	11	through	through	ADP
bjp-19567	125	12	erk	erk	NOUN
bjp-19567	125	13	or	or	CCONJ
bjp-19567	125	14	akt	akt	PROPN
bjp-19567	125	15	signaling	signal	VERB
bjp-19567	125	16	pathway	pathway	NOUN
bjp-19567	125	17	,	,	PUNCT
bjp-19567	125	18	we	we	PRON
bjp-19567	125	19	performed	perform	VERB
bjp-19567	125	20	western	western	ADJ
bjp-19567	125	21	blot	blot	NOUN
bjp-19567	125	22	technique	technique	NOUN
bjp-19567	125	23	to	to	PART
bjp-19567	125	24	check	check	VERB
bjp-19567	125	25	the	the	DET
bjp-19567	125	26	phosphorylation	phosphorylation	NOUN
bjp-19567	125	27	status	status	NOUN
bjp-19567	125	28	of	of	ADP
bjp-19567	125	29	erk	erk	PROPN
bjp-19567	125	30	and	and	CCONJ
bjp-19567	125	31	akt	akt	PROPN
bjp-19567	125	32	molecules	molecule	NOUN
bjp-19567	125	33	after	after	ADP
bjp-19567	125	34	nobiletin	nobiletin	NOUN
bjp-19567	125	35	treatment	treatment	NOUN
bjp-19567	125	36	.	.	PUNCT
bjp-19567	126	1	the	the	DET
bjp-19567	126	2	expression	expression	NOUN
bjp-19567	126	3	level	level	NOUN
bjp-19567	126	4	of	of	ADP
bjp-19567	126	5	p	p	PROPN
bjp-19567	126	6	-	-	PUNCT
bjp-19567	126	7	erk	erk	NOUN
bjp-19567	126	8	,	,	PUNCT
bjp-19567	126	9	p	p	PROPN
bjp-19567	126	10	-	-	PUNCT
bjp-19567	126	11	akt	akt	PROPN
bjp-19567	126	12	,	,	PUNCT
bjp-19567	126	13	erk	erk	PROPN
bjp-19567	126	14	and	and	CCONJ
bjp-19567	126	15	akt	akt	PROPN
bjp-19567	126	16	suggests	suggest	VERB
bjp-19567	126	17	that	that	SCONJ
bjp-19567	126	18	the	the	DET
bjp-19567	126	19	activation	activation	NOUN
bjp-19567	126	20	of	of	ADP
bjp-19567	126	21	erk	erk	NOUN
bjp-19567	126	22	signaling	signal	VERB
bjp-19567	126	23	pathway	pathway	NOUN
bjp-19567	126	24	might	might	AUX
bjp-19567	126	25	be	be	AUX
bjp-19567	126	26	involved	involve	VERB
bjp-19567	126	27	in	in	ADP
bjp-19567	126	28	stimulation	stimulation	NOUN
bjp-19567	126	29	of	of	ADP
bjp-19567	126	30	intrinsic	intrinsic	ADJ
bjp-19567	126	31	pathway	pathway	NOUN
bjp-19567	126	32	mediated	mediate	VERB
bjp-19567	126	33	by	by	ADP
bjp-19567	126	34	caspase-9	caspase-9	PROPN
bjp-19567	126	35	and	and	CCONJ
bjp-19567	126	36	-3	-3	PUNCT
bjp-19567	126	37	,	,	PUNCT
bjp-19567	126	38	leading	lead	VERB
bjp-19567	126	39	to	to	ADP
bjp-19567	126	40	apoptosis	apoptosis	NOUN
bjp-19567	126	41	.	.	PUNCT
bjp-19567	127	1	moreover	moreover	ADV
bjp-19567	127	2	,	,	PUNCT
bjp-19567	127	3	as	as	SCONJ
bjp-19567	127	4	akt	akt	PROPN
bjp-19567	127	5	signaling	signal	VERB
bjp-19567	127	6	pathways	pathway	NOUN
bjp-19567	127	7	is	be	AUX
bjp-19567	127	8	associated	associate	VERB
bjp-19567	127	9	with	with	ADP
bjp-19567	127	10	survival	survival	NOUN
bjp-19567	127	11	ability	ability	NOUN
bjp-19567	127	12	of	of	ADP
bjp-19567	127	13	any	any	DET
bjp-19567	127	14	cells	cell	NOUN
bjp-19567	127	15	,	,	PUNCT
bjp-19567	127	16	a	a	DET
bjp-19567	127	17	supperssion	supperssion	NOUN
bjp-19567	127	18	of	of	ADP
bjp-19567	127	19	phosphorylation	phosphorylation	NOUN
bjp-19567	127	20	of	of	ADP
bjp-19567	127	21	akt	akt	PROPN
bjp-19567	127	22	signaling	signal	VERB
bjp-19567	127	23	by	by	ADP
bjp-19567	127	24	nobiletin	nobiletin	NOUN
bjp-19567	127	25	may	may	AUX
bjp-19567	127	26	be	be	AUX
bjp-19567	127	27	responsible	responsible	ADJ
bjp-19567	127	28	for	for	ADP
bjp-19567	127	29	increased	increase	VERB
bjp-19567	127	30	apoptosis	apoptosis	NOUN
bjp-19567	127	31	observed	observe	VERB
bjp-19567	127	32	in	in	ADP
bjp-19567	127	33	case	case	NOUN
bjp-19567	127	34	of	of	ADP
bjp-19567	127	35	saos-2	saos-2	NUM
bjp-19567	127	36	cells	cell	NOUN
bjp-19567	127	37	.	.	PUNCT
bjp-19567	128	1	these	these	DET
bjp-19567	128	2	results	result	NOUN
bjp-19567	128	3	were	be	AUX
bjp-19567	128	4	also	also	ADV
bjp-19567	128	5	examined	examine	VERB
bjp-19567	128	6	and	and	CCONJ
bjp-19567	128	7	confirmed	confirm	VERB
bjp-19567	128	8	by	by	ADP
bjp-19567	128	9	inhibiting	inhibit	VERB
bjp-19567	128	10	and	and	CCONJ
bjp-19567	128	11	restoring	restore	VERB
bjp-19567	128	12	erk	erk	PROPN
bjp-19567	128	13	and	and	CCONJ
bjp-19567	128	14	akt	akt	PROPN
bjp-19567	128	15	signaling	signal	VERB
bjp-19567	128	16	pathways	pathway	NOUN
bjp-19567	128	17	,	,	PUNCT
bjp-19567	128	18	respectively	respectively	ADV
bjp-19567	128	19	.	.	PUNCT
bjp-19567	129	1	taken	take	VERB
bjp-19567	129	2	together	together	ADV
bjp-19567	129	3	,	,	PUNCT
bjp-19567	129	4	our	our	PRON
bjp-19567	129	5	results	result	NOUN
bjp-19567	129	6	demonstrate	demonstrate	VERB
bjp-19567	129	7	that	that	SCONJ
bjp-19567	129	8	nobiletin	nobiletin	NOUN
bjp-19567	129	9	can	can	AUX
bjp-19567	129	10	induce	induce	VERB
bjp-19567	129	11	anti	anti	ADJ
bjp-19567	129	12	-	-	ADJ
bjp-19567	129	13	proliferative	proliferative	ADJ
bjp-19567	129	14	effect	effect	NOUN
bjp-19567	129	15	on	on	ADP
bjp-19567	129	16	osteosarcoma	osteosarcoma	ADJ
bjp-19567	129	17	cells	cell	NOUN
bjp-19567	129	18	by	by	ADP
bjp-19567	129	19	induction	induction	NOUN
bjp-19567	129	20	of	of	ADP
bjp-19567	129	21	cell	cell	NOUN
bjp-19567	129	22	cycle	cycle	NOUN
bjp-19567	129	23	arrest	arrest	NOUN
bjp-19567	129	24	and	and	CCONJ
bjp-19567	129	25	apoptosis	apoptosis	NOUN
bjp-19567	129	26	by	by	ADP
bjp-19567	129	27	regulating	regulate	VERB
bjp-19567	129	28	erk	erk	PROPN
bjp-19567	129	29	and	and	CCONJ
bjp-19567	129	30	akt	akt	PROPN
bjp-19567	129	31	signaling	signal	VERB
bjp-19567	129	32	pathways	pathway	NOUN
bjp-19567	129	33	.	.	PUNCT
bjp-19567	130	1	this	this	DET
bjp-19567	130	2	study	study	NOUN
bjp-19567	130	3	results	result	NOUN
bjp-19567	130	4	are	be	AUX
bjp-19567	130	5	in	in	ADP
bjp-19567	130	6	agreement	agreement	NOUN
bjp-19567	130	7	with	with	ADP
bjp-19567	130	8	other	other	ADJ
bjp-19567	130	9	researches	research	NOUN
bjp-19567	130	10	which	which	PRON
bjp-19567	130	11	have	have	AUX
bjp-19567	130	12	successfully	successfully	ADV
bjp-19567	130	13	shown	show	VERB
bjp-19567	130	14	the	the	DET
bjp-19567	130	15	anti	anti	ADJ
bjp-19567	130	16	-	-	ADJ
bjp-19567	130	17	carcinogenic	carcinogenic	ADJ
bjp-19567	130	18	properties	property	NOUN
bjp-19567	130	19	of	of	ADP
bjp-19567	130	20	nobiletin	nobiletin	NOUN
bjp-19567	130	21	.	.	PUNCT
bjp-19567	131	1	current	current	ADJ
bjp-19567	131	2	finding	finding	NOUN
bjp-19567	131	3	clearly	clearly	ADV
bjp-19567	131	4	implicates	implicate	VERB
bjp-19567	131	5	nobiletin	nobiletin	NOUN
bjp-19567	131	6	as	as	ADP
bjp-19567	131	7	a	a	DET
bjp-19567	131	8	novel	novel	ADJ
bjp-19567	131	9	therapeutic	therapeutic	ADJ
bjp-19567	131	10	agent	agent	NOUN
bjp-19567	131	11	for	for	ADP
bjp-19567	131	12	the	the	DET
bjp-19567	131	13	treatment	treatment	NOUN
bjp-19567	131	14	of	of	ADP
bjp-19567	131	15	bone	bone	NOUN
bjp-19567	131	16	cancers	cancer	NOUN
bjp-19567	131	17	and	and	CCONJ
bjp-19567	131	18	further	far	ADV
bjp-19567	131	19	in	in	ADP
bjp-19567	131	20	vivo	vivo	ADJ
bjp-19567	131	21	studies	study	NOUN
bjp-19567	131	22	could	could	AUX
bjp-19567	131	23	establish	establish	VERB
bjp-19567	131	24	it	it	PRON
bjp-19567	131	25	as	as	ADP
bjp-19567	131	26	one	one	NUM
bjp-19567	131	27	of	of	ADP
bjp-19567	131	28	the	the	DET
bjp-19567	131	29	future	future	ADJ
bjp-19567	131	30	drug	drug	NOUN
bjp-19567	131	31	for	for	ADP
bjp-19567	131	32	bone	bone	NOUN
bjp-19567	131	33	cancer	cancer	NOUN
bjp-19567	131	34	treatment	treatment	NOUN
bjp-19567	131	35	.	.	PUNCT
bjp-19567	132	1	chemoprevention	chemoprevention	NOUN
bjp-19567	132	2	constitutes	constitute	VERB
bjp-19567	132	3	an	an	DET
bjp-19567	132	4	active	active	ADJ
bjp-19567	132	5	cancer	cancer	NOUN
bjp-19567	132	6	preventive	preventive	ADJ
bjp-19567	132	7	strategy	strategy	NOUN
bjp-19567	132	8	which	which	PRON
bjp-19567	132	9	could	could	AUX
bjp-19567	132	10	inhibit	inhibit	VERB
bjp-19567	132	11	,	,	PUNCT
bjp-19567	132	12	delay	delay	VERB
bjp-19567	132	13	or	or	CCONJ
bjp-19567	132	14	reverse	reverse	VERB
bjp-19567	132	15	human	human	ADJ
bjp-19567	132	16	carcinogenesis	carcinogenesis	NOUN
bjp-19567	132	17	.	.	PUNCT
bjp-19567	133	1	numerous	numerous	ADJ
bjp-19567	133	2	studies	study	NOUN
bjp-19567	133	3	have	have	AUX
bjp-19567	133	4	provided	provide	VERB
bjp-19567	133	5	substantial	substantial	ADJ
bjp-19567	133	6	evidence	evidence	NOUN
bjp-19567	133	7	that	that	SCONJ
bjp-19567	133	8	naturally	naturally	ADV
bjp-19567	133	9	products	product	NOUN
bjp-19567	133	10	or	or	CCONJ
bjp-19567	133	11	synthetic	synthetic	ADJ
bjp-19567	133	12	chemical	chemical	NOUN
bjp-19567	133	13	agents	agent	NOUN
bjp-19567	133	14	can	can	AUX
bjp-19567	133	15	block	block	VERB
bjp-19567	133	16	or	or	CCONJ
bjp-19567	133	17	reverse	reverse	VERB
bjp-19567	133	18	lethal	lethal	ADJ
bjp-19567	133	19	changes	change	NOUN
bjp-19567	133	20	in	in	ADP
bjp-19567	133	21	cellular	cellular	ADJ
bjp-19567	133	22	signaling	signaling	NOUN
bjp-19567	133	23	.	.	PUNCT
bjp-19567	134	1	given	give	VERB
bjp-19567	134	2	the	the	DET
bjp-19567	134	3	cytotoxic	cytotoxic	ADJ
bjp-19567	134	4	effects	effect	NOUN
bjp-19567	134	5	of	of	ADP
bjp-19567	134	6	synthetic	synthetic	ADJ
bjp-19567	134	7	chemical	chemical	ADJ
bjp-19567	134	8	agents	agent	NOUN
bjp-19567	134	9	,	,	PUNCT
bjp-19567	134	10	natural	natural	ADJ
bjp-19567	134	11	agents	agent	NOUN
bjp-19567	134	12	are	be	AUX
bjp-19567	134	13	the	the	DET
bjp-19567	134	14	need	need	NOUN
bjp-19567	134	15	of	of	ADP
bjp-19567	134	16	hour	hour	NOUN
bjp-19567	134	17	for	for	ADP
bjp-19567	134	18	treating	treat	VERB
bjp-19567	134	19	cancers	cancer	NOUN
bjp-19567	134	20	.	.	PUNCT
bjp-19567	135	1	in	in	ADP
bjp-19567	135	2	line	line	NOUN
bjp-19567	135	3	to	to	ADP
bjp-19567	135	4	this	this	DET
bjp-19567	135	5	requirement	requirement	NOUN
bjp-19567	135	6	,	,	PUNCT
bjp-19567	135	7	we	we	PRON
bjp-19567	135	8	have	have	AUX
bjp-19567	135	9	demonstrated	demonstrate	VERB
bjp-19567	135	10	that	that	SCONJ
bjp-19567	135	11	nobiletin	nobiletin	NOUN
bjp-19567	135	12	can	can	AUX
bjp-19567	135	13	exert	exert	VERB
bjp-19567	135	14	its	its	PRON
bjp-19567	135	15	anti	anti	ADJ
bjp-19567	135	16	-	-	ADJ
bjp-19567	135	17	proliferative	proliferative	ADJ
bjp-19567	135	18	effect	effect	NOUN
bjp-19567	135	19	on	on	ADP
bjp-19567	135	20	osteosarcoma	osteosarcoma	ADJ
bjp-19567	135	21	cells	cell	NOUN
bjp-19567	135	22	by	by	ADP
bjp-19567	135	23	regulating	regulate	VERB
bjp-19567	135	24	intrinsic	intrinsic	ADJ
bjp-19567	135	25	pathway	pathway	NOUN
bjp-19567	135	26	of	of	ADP
bjp-19567	135	27	apoptosis	apoptosis	NOUN
bjp-19567	135	28	through	through	ADP
bjp-19567	135	29	regulation	regulation	NOUN
bjp-19567	135	30	of	of	ADP
bjp-19567	135	31	erk	erk	NOUN
bjp-19567	135	32	signaling	signal	VERB
bjp-19567	135	33	pathway	pathway	NOUN
bjp-19567	135	34	.	.	PUNCT
bjp-19567	136	1	moreover	moreover	ADV
bjp-19567	136	2	,	,	PUNCT
bjp-19567	136	3	suppression	suppression	NOUN
bjp-19567	136	4	of	of	ADP
bjp-19567	136	5	akt	akt	PROPN
bjp-19567	136	6	signaling	signal	VERB
bjp-19567	136	7	pathways	pathway	NOUN
bjp-19567	136	8	further	far	ADV
bjp-19567	136	9	directs	direct	VERB
bjp-19567	136	10	the	the	DET
bjp-19567	136	11	cells	cell	NOUN
bjp-19567	136	12	toward	toward	ADP
bjp-19567	136	13	cell	cell	NOUN
bjp-19567	136	14	death	death	NOUN
bjp-19567	136	15	by	by	ADP
bjp-19567	136	16	nobiletin	nobiletin	NOUN
bjp-19567	136	17	.	.	PUNCT
bjp-19567	137	1	therefore	therefore	ADV
bjp-19567	137	2	,	,	PUNCT
bjp-19567	137	3	after	after	ADP
bjp-19567	137	4	in	in	ADP
bjp-19567	137	5	vivo	vivo	NOUN
bjp-19567	137	6	and	and	CCONJ
bjp-19567	137	7	clinical	clinical	ADJ
bjp-19567	137	8	trial	trial	NOUN
bjp-19567	137	9	,	,	PUNCT
bjp-19567	137	10	nobiletin	nobiletin	NOUN
bjp-19567	137	11	can	can	AUX
bjp-19567	137	12	be	be	AUX
bjp-19567	137	13	regarded	regard	VERB
bjp-19567	137	14	as	as	ADP
bjp-19567	137	15	future	future	ADJ
bjp-19567	137	16	anti	anti	ADJ
bjp-19567	137	17	-	-	ADJ
bjp-19567	137	18	cancerous	cancerous	ADJ
bjp-19567	137	19	agent	agent	NOUN
bjp-19567	137	20	to	to	PART
bjp-19567	137	21	treat	treat	VERB
bjp-19567	137	22	bone	bone	NOUN
bjp-19567	137	23	cancers	cancer	NOUN
bjp-19567	137	24	.	.	PUNCT
bjp-19567	138	1	acknowledgement	acknowledgement	NOUN
bjp-19567	138	2	this	this	DET
bjp-19567	138	3	work	work	NOUN
bjp-19567	138	4	was	be	AUX
bjp-19567	138	5	supported	support	VERB
bjp-19567	138	6	by	by	ADP
bjp-19567	138	7	natural	natural	ADJ
bjp-19567	138	8	science	science	NOUN
bjp-19567	138	9	foundation	foundation	PROPN
bjp-19567	138	10	of	of	ADP
bjp-19567	138	11	shandong	shandong	PROPN
bjp-19567	138	12	province	province	PROPN
bjp-19567	138	13	:	:	PUNCT
bjp-19567	138	14	zr2009cl027	zr2009cl027	PROPN
bjp-19567	138	15	;	;	PUNCT
bjp-19567	138	16	science	science	NOUN
bjp-19567	138	17	and	and	CCONJ
bjp-19567	138	18	technology	technology	PROPN
bjp-19567	138	19	bureau	bureau	PROPN
bjp-19567	138	20	of	of	ADP
bjp-19567	138	21	jinan	jinan	PROPN
bjp-19567	138	22	,	,	PUNCT
bjp-19567	138	23	science	science	NOUN
bjp-19567	138	24	and	and	CCONJ
bjp-19567	138	25	technology	technology	NOUN
bjp-19567	138	26	star	star	PROPN
bjp-19567	138	27	fund	fund	PROPN
bjp-19567	138	28	project	project	NOUN
bjp-19567	138	29	:	:	PUNCT
bjp-19567	138	30	20100118	20100118	NUM
bjp-19567	138	31	;	;	PUNCT
bjp-19567	138	32	shandong	shandong	PROPN
bjp-19567	138	33	academy	academy	PROPN
bjp-19567	138	34	of	of	ADP
bjp-19567	138	35	medical	medical	PROPN
bjp-19567	138	36	sciences	sciences	PROPN
bjp-19567	138	37	medical	medical	ADJ
bjp-19567	138	38	foundation：201023	foundation：201023	PROPN
bjp-19567	138	39	references	reference	VERB
bjp-19567	138	40	american	american	ADJ
bjp-19567	138	41	cancer	cancer	NOUN
bjp-19567	138	42	society	society	NOUN
bjp-19567	138	43	.	.	PUNCT
bjp-19567	139	1	cancer	cancer	NOUN
bjp-19567	139	2	:	:	PUNCT
bjp-19567	139	3	facts	fact	NOUN
bjp-19567	139	4	and	and	CCONJ
bjp-19567	139	5	figures	figure	NOUN
bjp-19567	139	6	.	.	PUNCT
bjp-19567	140	1	atlants	atlants	PROPN
bjp-19567	140	2	,	,	PUNCT
bjp-19567	140	3	ga	ga	PROPN
bjp-19567	140	4	,	,	PUNCT
bjp-19567	140	5	american	american	ADJ
bjp-19567	140	6	cancer	cancer	NOUN
bjp-19567	140	7	society	society	NOUN
bjp-19567	140	8	,	,	PUNCT
bjp-19567	140	9	2014	2014	NUM
bjp-19567	140	10	.	.	PUNCT
bjp-19567	141	1	aoki	aoki	PROPN
bjp-19567	141	2	k	k	PROPN
bjp-19567	141	3	,	,	PUNCT
bjp-19567	141	4	yokosuka	yokosuka	PROPN
bjp-19567	141	5	a	a	PROPN
bjp-19567	141	6	,	,	PUNCT
bjp-19567	141	7	mimaki	mimaki	VERB
bjp-19567	141	8	y	y	NOUN
bjp-19567	141	9	,	,	PUNCT
bjp-19567	141	10	fukunaga	fukunaga	PROPN
bjp-19567	141	11	k	k	PROPN
bjp-19567	141	12	,	,	PUNCT
bjp-19567	141	13	yamakuni	yamakuni	PROPN
bjp-19567	141	14	t.	t.	NOUN
bjp-19567	141	15	nobiletin	nobiletin	PROPN
bjp-19567	141	16	induces	induce	VERB
bjp-19567	141	17	inhibitions	inhibition	NOUN
bjp-19567	141	18	of	of	ADP
bjp-19567	141	19	ras	ras	NOUN
bjp-19567	141	20	activity	activity	NOUN
bjp-19567	141	21	and	and	CCONJ
bjp-19567	141	22	mitogenactivated	mitogenactivate	VERB
bjp-19567	141	23	protein	protein	NOUN
bjp-19567	141	24	kinase	kinase	PROPN
bjp-19567	141	25	kinase	kinase	PROPN
bjp-19567	141	26	/	/	SYM
bjp-19567	141	27	extracellular	extracellular	ADJ
bjp-19567	141	28	signalregulated	signalregulate	VERB
bjp-19567	141	29	kinase	kinase	NOUN
bjp-19567	141	30	signaling	signal	VERB
bjp-19567	141	31	to	to	PART
bjp-19567	141	32	suppress	suppress	VERB
bjp-19567	141	33	cell	cell	NOUN
bjp-19567	141	34	proliferation	proliferation	NOUN
bjp-19567	141	35	in	in	ADP
bjp-19567	141	36	c6	c6	PROPN
bjp-19567	141	37	rat	rat	NOUN
bjp-19567	141	38	glioma	glioma	NOUN
bjp-19567	141	39	cells	cell	NOUN
bjp-19567	141	40	.	.	PUNCT
bjp-19567	142	1	biol	biol	PROPN
bjp-19567	142	2	pharm	pharm	PROPN
bjp-19567	142	3	bull	bull	NOUN
bjp-19567	142	4	.	.	PUNCT
bjp-19567	143	1	2013	2013	NUM
bjp-19567	143	2	;	;	PUNCT
bjp-19567	143	3	36	36	NUM
bjp-19567	143	4	:	:	SYM
bjp-19567	143	5	540	540	NUM
bjp-19567	143	6	-	-	SYM
bjp-19567	143	7	47	47	NUM
bjp-19567	143	8	.	.	PUNCT
bjp-19567	144	1	chen	chen	PROPN
bjp-19567	144	2	c	c	PROPN
bjp-19567	144	3	,	,	PUNCT
bjp-19567	144	4	ono	ono	PROPN
bjp-19567	144	5	m	m	PROPN
bjp-19567	144	6	,	,	PUNCT
bjp-19567	144	7	takeshima	takeshima	PROPN
bjp-19567	144	8	m	m	PROPN
bjp-19567	144	9	,	,	PUNCT
bjp-19567	144	10	nakano	nakano	PROPN
bjp-19567	144	11	s.	s.	PROPN
bjp-19567	144	12	anti	anti	PROPN
bjp-19567	144	13	-	-	ADJ
bjp-19567	144	14	proliferative	proliferative	ADJ
bjp-19567	144	15	and	and	CCONJ
bjp-19567	144	16	apoptosis	apoptosis	NOUN
bjp-19567	144	17	-	-	PUNCT
bjp-19567	144	18	inducing	induce	VERB
bjp-19567	144	19	activity	activity	NOUN
bjp-19567	144	20	of	of	ADP
bjp-19567	144	21	nobiletin	nobiletin	NOUN
bjp-19567	144	22	against	against	ADP
bjp-19567	144	23	three	three	NUM
bjp-19567	144	24	subtypes	subtype	NOUN
bjp-19567	144	25	of	of	ADP
bjp-19567	144	26	human	human	ADJ
bjp-19567	144	27	breast	breast	NOUN
bjp-19567	144	28	cancer	cancer	NOUN
bjp-19567	144	29	cell	cell	NOUN
bjp-19567	144	30	lines	line	NOUN
bjp-19567	144	31	.	.	PUNCT
bjp-19567	145	1	anti	anti	ADJ
bjp-19567	145	2	-	-	ADJ
bjp-19567	145	3	cancer	cancer	ADJ
bjp-19567	145	4	res	re	NOUN
bjp-19567	145	5	.	.	PUNCT
bjp-19567	145	6	2014	2014	NUM
bjp-19567	145	7	;	;	PUNCT
bjp-19567	145	8	34	34	NUM
bjp-19567	145	9	:	:	SYM
bjp-19567	145	10	1785	1785	NUM
bjp-19567	145	11	-	-	SYM
bjp-19567	145	12	92	92	NUM
bjp-19567	145	13	.	.	PUNCT
bjp-19567	146	1	gullett	gullett	VERB
bjp-19567	146	2	np	np	PROPN
bjp-19567	146	3	,	,	PUNCT
bjp-19567	146	4	ruhul	ruhul	PROPN
bjp-19567	146	5	amin	amin	PROPN
bjp-19567	146	6	ar	ar	PROPN
bjp-19567	146	7	,	,	PUNCT
bjp-19567	146	8	bayraktar	bayraktar	PROPN
bjp-19567	146	9	s	s	PROPN
bjp-19567	146	10	,	,	PUNCT
bjp-19567	146	11	pezzuto	pezzuto	PROPN
bjp-19567	146	12	jm	jm	PROPN
bjp-19567	146	13	,	,	PUNCT
bjp-19567	146	14	shin	shin	PROPN
bjp-19567	146	15	dm	dm	PROPN
bjp-19567	146	16	,	,	PUNCT
bjp-19567	146	17	khuri	khuri	NOUN
bjp-19567	146	18	fr	fr	NOUN
bjp-19567	146	19	,	,	PUNCT
bjp-19567	146	20	aggarwal	aggarwal	PROPN
bjp-19567	146	21	bb	bb	PROPN
bjp-19567	146	22	,	,	PUNCT
bjp-19567	146	23	surh	surh	PROPN
bjp-19567	146	24	yj	yj	PROPN
bjp-19567	146	25	,	,	PUNCT
bjp-19567	146	26	kucuk	kucuk	NOUN
bjp-19567	146	27	o.	o.	NOUN
bjp-19567	146	28	cancer	cancer	NOUN
bjp-19567	146	29	prevention	prevention	NOUN
bjp-19567	146	30	with	with	ADP
bjp-19567	146	31	natural	natural	ADJ
bjp-19567	146	32	compounds	compound	NOUN
bjp-19567	146	33	.	.	PUNCT
bjp-19567	147	1	semin	semin	PROPN
bjp-19567	147	2	oncol	oncol	PROPN
bjp-19567	147	3	.	.	PUNCT
bjp-19567	148	1	2010	2010	NUM
bjp-19567	148	2	;	;	PUNCT
bjp-19567	148	3	37	37	NUM
bjp-19567	148	4	:	:	SYM
bjp-19567	148	5	258	258	NUM
bjp-19567	148	6	-	-	SYM
bjp-19567	148	7	81	81	NUM
bjp-19567	148	8	.	.	PUNCT
bjp-19567	149	1	harborne	harborne	PROPN
bjp-19567	149	2	jb	jb	PROPN
bjp-19567	149	3	,	,	PUNCT
bjp-19567	149	4	williams	williams	PROPN
bjp-19567	149	5	ca	ca	PROPN
bjp-19567	149	6	.	.	PUNCT
bjp-19567	149	7	advances	advance	NOUN
bjp-19567	149	8	in	in	ADP
bjp-19567	149	9	flavonoid	flavonoid	PROPN
bjp-19567	149	10	research	research	NOUN
bjp-19567	149	11	since	since	SCONJ
bjp-19567	149	12	1992	1992	NUM
bjp-19567	149	13	.	.	PUNCT
bjp-19567	150	1	phytochemistry	phytochemistry	NOUN
bjp-19567	150	2	2000	2000	NUM
bjp-19567	150	3	;	;	PUNCT
bjp-19567	150	4	55	55	NUM
bjp-19567	150	5	:	:	PUNCT
bjp-19567	150	6	481	481	NUM
bjp-19567	150	7	-	-	SYM
bjp-19567	150	8	504	504	NUM
bjp-19567	150	9	.	.	PUNCT
bjp-19567	151	1	hartwell	hartwell	PROPN
bjp-19567	151	2	lh	lh	PROPN
bjp-19567	151	3	,	,	PUNCT
bjp-19567	151	4	kastan	kastan	PROPN
bjp-19567	151	5	mb	mb	PROPN
bjp-19567	151	6	.	.	PROPN
bjp-19567	151	7	cell	cell	NOUN
bjp-19567	151	8	cycle	cycle	NOUN
bjp-19567	151	9	control	control	NOUN
bjp-19567	151	10	and	and	CCONJ
bjp-19567	151	11	cancer	cancer	NOUN
bjp-19567	151	12	.	.	PUNCT
bjp-19567	152	1	science	science	NOUN
bjp-19567	152	2	1994	1994	NUM
bjp-19567	152	3	;	;	PUNCT
bjp-19567	152	4	266	266	NUM
bjp-19567	152	5	:	:	PUNCT
bjp-19567	152	6	1821	1821	NUM
bjp-19567	152	7	-	-	SYM
bjp-19567	152	8	28	28	NUM
bjp-19567	152	9	.	.	PUNCT
bjp-19567	153	1	hartwell	hartwell	PROPN
bjp-19567	153	2	lh	lh	PROPN
bjp-19567	153	3	,	,	PUNCT
bjp-19567	153	4	weinert	weinert	PROPN
bjp-19567	153	5	ta	ta	PROPN
bjp-19567	153	6	.	.	PUNCT
bjp-19567	154	1	checkpoints	checkpoint	NOUN
bjp-19567	154	2	:	:	PUNCT
bjp-19567	154	3	controls	control	NOUN
bjp-19567	154	4	that	that	PRON
bjp-19567	154	5	ensure	ensure	VERB
bjp-19567	154	6	the	the	DET
bjp-19567	154	7	order	order	NOUN
bjp-19567	154	8	of	of	ADP
bjp-19567	154	9	cell	cell	NOUN
bjp-19567	154	10	cycle	cycle	NOUN
bjp-19567	154	11	events	event	NOUN
bjp-19567	154	12	.	.	PUNCT
bjp-19567	155	1	science	science	NOUN
bjp-19567	155	2	1989	1989	NUM
bjp-19567	155	3	;	;	PUNCT
bjp-19567	155	4	246	246	NUM
bjp-19567	155	5	:	:	PUNCT
bjp-19567	155	6	629	629	NUM
bjp-19567	155	7	-	-	SYM
bjp-19567	155	8	34	34	NUM
bjp-19567	155	9	.	.	PUNCT
bjp-19567	155	10	hunt	hunt	NOUN
bjp-19567	155	11	tr	tr	VERB
bjp-19567	155	12	,	,	PUNCT
bjp-19567	155	13	schwappach	schwappach	PROPN
bjp-19567	155	14	jr	jr	PROPN
bjp-19567	155	15	,	,	PUNCT
bjp-19567	155	16	anderson	anderson	PROPN
bjp-19567	155	17	hc	hc	PROPN
bjp-19567	155	18	.	.	PUNCT
bjp-19567	155	19	healing	healing	NOUN
bjp-19567	155	20	of	of	ADP
bjp-19567	155	21	a	a	DET
bjp-19567	155	22	segmental	segmental	ADJ
bjp-19567	155	23	defect	defect	NOUN
bjp-19567	155	24	in	in	ADP
bjp-19567	155	25	the	the	DET
bjp-19567	155	26	rat	rat	NOUN
bjp-19567	155	27	femur	femur	NOUN
bjp-19567	155	28	with	with	ADP
bjp-19567	155	29	use	use	NOUN
bjp-19567	155	30	of	of	ADP
bjp-19567	155	31	an	an	DET
bjp-19567	155	32	extract	extract	NOUN
bjp-19567	155	33	from	from	ADP
bjp-19567	155	34	a	a	DET
bjp-19567	155	35	cultured	cultured	ADJ
bjp-19567	155	36	human	human	ADJ
bjp-19567	155	37	osteosarcoma	osteosarcoma	ADJ
bjp-19567	155	38	cell	cell	NOUN
bjp-19567	155	39	-	-	PUNCT
bjp-19567	155	40	line	line	NOUN
bjp-19567	155	41	(	(	PUNCT
bjp-19567	155	42	saos-2	saos-2	NUM
bjp-19567	155	43	)	)	PUNCT
bjp-19567	155	44	.	.	PUNCT
bjp-19567	156	1	a	a	DET
bjp-19567	156	2	preliminary	preliminary	ADJ
bjp-19567	156	3	report	report	NOUN
bjp-19567	156	4	.	.	PUNCT
bjp-19567	157	1	j	j	PROPN
bjp-19567	157	2	bone	bone	PROPN
bjp-19567	157	3	joint	joint	ADJ
bjp-19567	157	4	surg	surg	NOUN
bjp-19567	157	5	am	be	AUX
bjp-19567	157	6	.	.	PUNCT
bjp-19567	157	7	1996	1996	NUM
bjp-19567	157	8	;	;	PUNCT
bjp-19567	157	9	78	78	NUM
bjp-19567	157	10	:	:	SYM
bjp-19567	157	11	41	41	NUM
bjp-19567	157	12	-	-	SYM
bjp-19567	157	13	48	48	NUM
bjp-19567	157	14	.	.	PUNCT
bjp-19567	158	1	ishii	ishii	PROPN
bjp-19567	158	2	k	k	PROPN
bjp-19567	158	3	,	,	PUNCT
bjp-19567	158	4	tanaka	tanaka	PROPN
bjp-19567	158	5	s	s	PROPN
bjp-19567	158	6	,	,	PUNCT
bjp-19567	158	7	kagami	kagami	PROPN
bjp-19567	158	8	k	k	PROPN
bjp-19567	158	9	,	,	PUNCT
bjp-19567	158	10	henmi	henmi	PROPN
bjp-19567	158	11	k	k	NOUN
bjp-19567	158	12	,	,	PUNCT
bjp-19567	158	13	toyoda	toyoda	PROPN
bjp-19567	158	14	h	h	PROPN
bjp-19567	158	15	,	,	PUNCT
bjp-19567	158	16	bangladesh	bangladesh	PROPN
bjp-19567	158	17	j	j	PROPN
bjp-19567	158	18	pharmacol	pharmacol	PROPN
bjp-19567	158	19	2014	2014	NUM
bjp-19567	158	20	;	;	PUNCT
bjp-19567	158	21	9	9	NUM
bjp-19567	158	22	:	:	SYM
bjp-19567	158	23	406	406	NUM
bjp-19567	158	24	-	-	SYM
bjp-19567	158	25	412	412	NUM
bjp-19567	158	26	411	411	NUM
bjp-19567	158	27	kaise	kaise	PROPN
bjp-19567	158	28	t	t	PROPN
bjp-19567	158	29	,	,	PUNCT
bjp-19567	158	30	hirano	hirano	PROPN
bjp-19567	158	31	t.	t.	PROPN
bjp-19567	158	32	effects	effect	NOUN
bjp-19567	158	33	of	of	ADP
bjp-19567	158	34	naturally	naturally	ADV
bjp-19567	158	35	occurring	occur	VERB
bjp-19567	158	36	polymethyoxyflavonoids	polymethyoxyflavonoid	NOUN
bjp-19567	158	37	on	on	ADP
bjp-19567	158	38	cell	cell	NOUN
bjp-19567	158	39	growth	growth	NOUN
bjp-19567	158	40	,	,	PUNCT
bjp-19567	158	41	p	p	NOUN
bjp-19567	158	42	-	-	PUNCT
bjp-19567	158	43	glycoprotein	glycoprotein	NOUN
bjp-19567	158	44	function	function	NOUN
bjp-19567	158	45	,	,	PUNCT
bjp-19567	158	46	cell	cell	NOUN
bjp-19567	158	47	cycle	cycle	NOUN
bjp-19567	158	48	,	,	PUNCT
bjp-19567	158	49	and	and	CCONJ
bjp-19567	158	50	apoptosis	apoptosis	NOUN
bjp-19567	158	51	of	of	ADP
bjp-19567	158	52	daunorubicin	daunorubicin	NOUN
bjp-19567	158	53	-	-	PUNCT
bjp-19567	158	54	resistant	resistant	ADJ
bjp-19567	158	55	t	t	NOUN
bjp-19567	158	56	lymphoblastoid	lymphoblastoid	NOUN
bjp-19567	158	57	leukemia	leukemia	NOUN
bjp-19567	158	58	cells	cell	NOUN
bjp-19567	158	59	.	.	PUNCT
bjp-19567	159	1	cancer	cancer	NOUN
bjp-19567	159	2	invest	invest	PROPN
bjp-19567	159	3	.	.	PUNCT
bjp-19567	160	1	2010	2010	NUM
bjp-19567	160	2	;	;	PUNCT
bjp-19567	160	3	28	28	NUM
bjp-19567	160	4	:	:	SYM
bjp-19567	160	5	22029	22029	NUM
bjp-19567	160	6	.	.	PUNCT
bjp-19567	161	1	kim	kim	PROPN
bjp-19567	161	2	h	h	PROPN
bjp-19567	161	3	,	,	PUNCT
bjp-19567	161	4	seo	seo	NOUN
bjp-19567	161	5	e	e	PROPN
bjp-19567	161	6	-	-	NOUN
bjp-19567	161	7	m	m	PROPN
bjp-19567	161	8	,	,	PUNCT
bjp-19567	161	9	sharma	sharma	PROPN
bjp-19567	161	10	ar	ar	PROPN
bjp-19567	161	11	,	,	PUNCT
bjp-19567	161	12	ganbold	ganbold	ADJ
bjp-19567	161	13	b	b	PROPN
bjp-19567	161	14	,	,	PUNCT
bjp-19567	161	15	park	park	PROPN
bjp-19567	161	16	j	j	PROPN
bjp-19567	161	17	,	,	PUNCT
bjp-19567	161	18	sharma	sharma	PROPN
bjp-19567	161	19	g	g	PROPN
bjp-19567	161	20	,	,	PUNCT
bjp-19567	161	21	kang	kang	PROPN
bjp-19567	161	22	yh	yh	PROPN
bjp-19567	161	23	,	,	PUNCT
bjp-19567	161	24	song	song	NOUN
bjp-19567	161	25	dk	dk	PROPN
bjp-19567	161	26	,	,	PUNCT
bjp-19567	161	27	lee	lee	PROPN
bjp-19567	161	28	ss	ss	PROPN
bjp-19567	161	29	,	,	PUNCT
bjp-19567	161	30	nam	nam	PROPN
bjp-19567	161	31	js	js	PROPN
bjp-19567	161	32	.	.	PUNCT
bjp-19567	162	1	regulation	regulation	NOUN
bjp-19567	162	2	of	of	ADP
bjp-19567	162	3	wnt	wnt	NOUN
bjp-19567	162	4	signaling	signal	VERB
bjp-19567	162	5	activity	activity	NOUN
bjp-19567	162	6	for	for	ADP
bjp-19567	162	7	growth	growth	NOUN
bjp-19567	162	8	suppression	suppression	NOUN
bjp-19567	162	9	induced	induce	VERB
bjp-19567	162	10	by	by	ADP
bjp-19567	162	11	quercetin	quercetin	NOUN
bjp-19567	162	12	in	in	ADP
bjp-19567	162	13	4t1	4t1	NUM
bjp-19567	162	14	murine	murine	ADJ
bjp-19567	162	15	mammary	mammary	ADJ
bjp-19567	162	16	cancer	cancer	NOUN
bjp-19567	162	17	cells	cell	NOUN
bjp-19567	162	18	.	.	PUNCT
bjp-19567	163	1	int	int	NOUN
bjp-19567	163	2	j	j	PROPN
bjp-19567	163	3	oncol	oncol	ADJ
bjp-19567	163	4	.	.	PUNCT
bjp-19567	164	1	2013	2013	NUM
bjp-19567	164	2	;	;	PUNCT
bjp-19567	164	3	43	43	NUM
bjp-19567	164	4	:	:	PUNCT
bjp-19567	164	5	1319	1319	NUM
bjp-19567	164	6	-	-	SYM
bjp-19567	164	7	25	25	NUM
bjp-19567	164	8	.	.	PUNCT
bjp-19567	165	1	kroemer	kroemer	PROPN
bjp-19567	165	2	g	g	PROPN
bjp-19567	165	3	,	,	PUNCT
bjp-19567	165	4	galluzzi	galluzzi	NOUN
bjp-19567	165	5	l	l	NOUN
bjp-19567	165	6	,	,	PUNCT
bjp-19567	165	7	brenner	brenner	PROPN
bjp-19567	165	8	c.	c.	PROPN
bjp-19567	165	9	mitochondrial	mitochondrial	ADJ
bjp-19567	165	10	membrane	membrane	NOUN
bjp-19567	165	11	permeabilization	permeabilization	NOUN
bjp-19567	165	12	in	in	ADP
bjp-19567	165	13	cell	cell	NOUN
bjp-19567	165	14	death	death	NOUN
bjp-19567	165	15	.	.	PUNCT
bjp-19567	166	1	physiol	physiol	PROPN
bjp-19567	166	2	rev	rev	VERB
bjp-19567	166	3	.	.	PROPN
bjp-19567	166	4	2007	2007	NUM
bjp-19567	166	5	;	;	PUNCT
bjp-19567	166	6	87	87	NUM
bjp-19567	166	7	:	:	SYM
bjp-19567	166	8	99	99	NUM
bjp-19567	166	9	-	-	SYM
bjp-19567	166	10	163	163	NUM
bjp-19567	166	11	.	.	PUNCT
bjp-19567	167	1	lai	lai	PROPN
bjp-19567	167	2	cs	cs	PROPN
bjp-19567	167	3	,	,	PUNCT
bjp-19567	167	4	li	li	PROPN
bjp-19567	167	5	s	s	PROPN
bjp-19567	167	6	,	,	PUNCT
bjp-19567	167	7	chai	chai	NOUN
bjp-19567	167	8	cy	cy	PROPN
bjp-19567	167	9	,	,	PUNCT
bjp-19567	167	10	lo	lo	PROPN
bjp-19567	167	11	cy	cy	PROPN
bjp-19567	167	12	,	,	PUNCT
bjp-19567	167	13	dushenkov	dushenkov	PROPN
bjp-19567	167	14	s	s	PROPN
bjp-19567	167	15	,	,	PUNCT
bjp-19567	167	16	ho	ho	PROPN
bjp-19567	167	17	ct	ct	PROPN
bjp-19567	167	18	,	,	PUNCT
bjp-19567	167	19	pan	pan	PROPN
bjp-19567	167	20	mh	mh	PROPN
bjp-19567	167	21	,	,	PUNCT
bjp-19567	167	22	wang	wang	PROPN
bjp-19567	167	23	yj	yj	PROPN
bjp-19567	167	24	.	.	PROPN
bjp-19567	167	25	anti	anti	ADJ
bjp-19567	167	26	-	-	ADJ
bjp-19567	167	27	inflammatory	inflammatory	ADJ
bjp-19567	167	28	and	and	CCONJ
bjp-19567	167	29	antitumor	antitumor	PROPN
bjp-19567	167	30	promotional	promotional	ADJ
bjp-19567	167	31	effects	effect	NOUN
bjp-19567	167	32	of	of	ADP
bjp-19567	167	33	a	a	DET
bjp-19567	167	34	novel	novel	ADJ
bjp-19567	167	35	urinary	urinary	ADJ
bjp-19567	167	36	metabolite	metabolite	NOUN
bjp-19567	167	37	,	,	PUNCT
bjp-19567	167	38	3',4'-didemethyl	3',4'-didemethyl	NUM
bjp-19567	167	39	nobiletin	nobiletin	NOUN
bjp-19567	167	40	,	,	PUNCT
bjp-19567	167	41	derived	derive	VERB
bjp-19567	167	42	from	from	ADP
bjp-19567	167	43	nobiletin	nobiletin	NOUN
bjp-19567	167	44	.	.	PUNCT
bjp-19567	168	1	carcinogenesis	carcinogenesis	NOUN
bjp-19567	168	2	2008	2008	NUM
bjp-19567	168	3	;	;	PUNCT
bjp-19567	168	4	29	29	NUM
bjp-19567	168	5	:	:	SYM
bjp-19567	168	6	2415	2415	NUM
bjp-19567	168	7	-	-	SYM
bjp-19567	168	8	24	24	NUM
bjp-19567	168	9	.	.	PUNCT
bjp-19567	169	1	lai	lai	PROPN
bjp-19567	169	2	e	e	PROPN
bjp-19567	169	3	,	,	PUNCT
bjp-19567	169	4	teodoro	teodoro	PROPN
bjp-19567	169	5	t	t	PROPN
bjp-19567	169	6	,	,	PUNCT
bjp-19567	169	7	volchuk	volchuk	ADJ
bjp-19567	169	8	a.	a.	NOUN
bjp-19567	169	9	endoplasmic	endoplasmic	ADJ
bjp-19567	169	10	reticulum	reticulum	NOUN
bjp-19567	169	11	stress	stress	NOUN
bjp-19567	169	12	:	:	PUNCT
bjp-19567	169	13	signaling	signal	VERB
bjp-19567	169	14	the	the	DET
bjp-19567	169	15	unfolded	unfolded	ADJ
bjp-19567	169	16	protein	protein	NOUN
bjp-19567	169	17	response	response	NOUN
bjp-19567	169	18	.	.	PUNCT
bjp-19567	170	1	physiology	physiology	NOUN
bjp-19567	170	2	(	(	PUNCT
bjp-19567	170	3	bethesda	bethesda	NOUN
bjp-19567	170	4	)	)	PUNCT
bjp-19567	170	5	2007	2007	NUM
bjp-19567	170	6	;	;	PUNCT
bjp-19567	170	7	22	22	NUM
bjp-19567	170	8	:	:	SYM
bjp-19567	170	9	193	193	NUM
bjp-19567	170	10	-	-	SYM
bjp-19567	170	11	201	201	NUM
bjp-19567	170	12	.	.	PUNCT
bjp-19567	171	1	legrand	legrand	PROPN
bjp-19567	171	2	c	c	PROPN
bjp-19567	171	3	,	,	PUNCT
bjp-19567	171	4	bour	bour	PROPN
bjp-19567	171	5	jm	jm	PROPN
bjp-19567	171	6	,	,	PUNCT
bjp-19567	171	7	jacob	jacob	PROPN
bjp-19567	171	8	c	c	PROPN
bjp-19567	171	9	,	,	PUNCT
bjp-19567	171	10	capiaumont	capiaumont	PROPN
bjp-19567	171	11	j	j	PROPN
bjp-19567	171	12	,	,	PUNCT
bjp-19567	171	13	martial	martial	NOUN
bjp-19567	171	14	a	a	PRON
bjp-19567	171	15	,	,	PUNCT
bjp-19567	171	16	marc	marc	PROPN
bjp-19567	171	17	a	a	PROPN
bjp-19567	171	18	,	,	PUNCT
bjp-19567	171	19	wudtke	wudtke	NOUN
bjp-19567	171	20	m	m	PROPN
bjp-19567	171	21	,	,	PUNCT
bjp-19567	171	22	kretzmer	kretzmer	PROPN
bjp-19567	171	23	g	g	PROPN
bjp-19567	171	24	,	,	PUNCT
bjp-19567	171	25	demangel	demangel	NOUN
bjp-19567	171	26	c	c	NOUN
bjp-19567	171	27	,	,	PUNCT
bjp-19567	171	28	duval	duval	PROPN
bjp-19567	171	29	d	d	PROPN
bjp-19567	171	30	,	,	PUNCT
bjp-19567	171	31	hache	hache	PROPN
bjp-19567	171	32	j.	j.	PROPN
bjp-19567	171	33	lactate	lactate	PROPN
bjp-19567	171	34	dehydrogenase	dehydrogenase	NOUN
bjp-19567	171	35	(	(	PUNCT
bjp-19567	171	36	ldh	ldh	NOUN
bjp-19567	171	37	)	)	PUNCT
bjp-19567	171	38	activity	activity	NOUN
bjp-19567	171	39	of	of	ADP
bjp-19567	171	40	the	the	DET
bjp-19567	171	41	cultured	cultured	ADJ
bjp-19567	171	42	eukaryotic	eukaryotic	ADJ
bjp-19567	171	43	cells	cell	NOUN
bjp-19567	171	44	as	as	ADP
bjp-19567	171	45	marker	marker	NOUN
bjp-19567	171	46	of	of	ADP
bjp-19567	171	47	the	the	DET
bjp-19567	171	48	number	number	NOUN
bjp-19567	171	49	of	of	ADP
bjp-19567	171	50	dead	dead	ADJ
bjp-19567	171	51	cells	cell	NOUN
bjp-19567	171	52	in	in	ADP
bjp-19567	171	53	the	the	DET
bjp-19567	171	54	medium	medium	NOUN
bjp-19567	171	55	.	.	PUNCT
bjp-19567	172	1	j	j	PROPN
bjp-19567	172	2	biotechnol	biotechnol	PROPN
bjp-19567	172	3	.	.	PUNCT
bjp-19567	172	4	1992	1992	NUM
bjp-19567	172	5	;	;	PUNCT
bjp-19567	172	6	25	25	NUM
bjp-19567	172	7	:	:	SYM
bjp-19567	172	8	231	231	NUM
bjp-19567	172	9	-	-	SYM
bjp-19567	172	10	43	43	NUM
bjp-19567	172	11	.	.	PUNCT
bjp-19567	173	1	li	li	PROPN
bjp-19567	173	2	rw	rw	PROPN
bjp-19567	173	3	,	,	PUNCT
bjp-19567	173	4	theriault	theriault	PROPN
bjp-19567	173	5	ag	ag	PROPN
bjp-19567	173	6	,	,	PUNCT
bjp-19567	173	7	au	au	PROPN
bjp-19567	173	8	k	k	PROPN
bjp-19567	173	9	,	,	PUNCT
bjp-19567	173	10	douglas	douglas	PROPN
bjp-19567	173	11	td	td	PROPN
bjp-19567	173	12	,	,	PUNCT
bjp-19567	173	13	casaschi	casaschi	PROPN
bjp-19567	173	14	a	a	PRON
bjp-19567	173	15	,	,	PUNCT
bjp-19567	173	16	kurowska	kurowska	VERB
bjp-19567	173	17	em	em	PRON
bjp-19567	173	18	,	,	PUNCT
bjp-19567	173	19	mukherjee	mukherjee	PROPN
bjp-19567	173	20	r.	r.	PROPN
bjp-19567	173	21	citrus	citrus	PROPN
bjp-19567	173	22	polymethoxylated	polymethoxylate	VERB
bjp-19567	173	23	flavones	flavone	NOUN
bjp-19567	173	24	improve	improve	VERB
bjp-19567	173	25	lipid	lipid	NOUN
bjp-19567	173	26	and	and	CCONJ
bjp-19567	173	27	glucose	glucose	NOUN
bjp-19567	173	28	homeostasis	homeostasis	NOUN
bjp-19567	173	29	and	and	CCONJ
bjp-19567	173	30	modulate	modulate	VERB
bjp-19567	173	31	adipocytokines	adipocytokine	NOUN
bjp-19567	173	32	in	in	ADP
bjp-19567	173	33	fructose	fructose	NOUN
bjp-19567	173	34	-	-	PUNCT
bjp-19567	173	35	induced	induce	VERB
bjp-19567	173	36	insulin	insulin	NOUN
bjp-19567	173	37	resistant	resistant	ADJ
bjp-19567	173	38	hamsters	hamster	NOUN
bjp-19567	173	39	.	.	PUNCT
bjp-19567	174	1	life	life	PROPN
bjp-19567	174	2	sci	sci	PROPN
bjp-19567	174	3	.	.	PROPN
bjp-19567	174	4	2006	2006	NUM
bjp-19567	174	5	;	;	PUNCT
bjp-19567	174	6	79	79	NUM
bjp-19567	174	7	:	:	SYM
bjp-19567	174	8	365	365	NUM
bjp-19567	174	9	-	-	SYM
bjp-19567	174	10	73	73	NUM
bjp-19567	174	11	.	.	PUNCT
bjp-19567	175	1	luo	luo	PROPN
bjp-19567	175	2	g	g	PROPN
bjp-19567	175	3	,	,	PUNCT
bjp-19567	175	4	guan	guan	PROPN
bjp-19567	175	5	x	x	PROPN
bjp-19567	175	6	,	,	PUNCT
bjp-19567	175	7	zhou	zhou	PROPN
bjp-19567	175	8	l.	l.	PROPN
bjp-19567	175	9	apoptotic	apoptotic	ADJ
bjp-19567	175	10	effect	effect	NOUN
bjp-19567	175	11	of	of	ADP
bjp-19567	175	12	citrus	citrus	NOUN
bjp-19567	175	13	fruit	fruit	NOUN
bjp-19567	175	14	extract	extract	VERB
bjp-19567	175	15	nobiletin	nobiletin	NOUN
bjp-19567	175	16	on	on	ADP
bjp-19567	175	17	lung	lung	NOUN
bjp-19567	175	18	cancer	cancer	NOUN
bjp-19567	175	19	cell	cell	NOUN
bjp-19567	175	20	line	line	NOUN
bjp-19567	175	21	a549	a549	PROPN
bjp-19567	175	22	in	in	ADP
bjp-19567	175	23	vitro	vitro	X
bjp-19567	175	24	and	and	CCONJ
bjp-19567	175	25	in	in	ADP
bjp-19567	175	26	vivo	vivo	NOUN
bjp-19567	175	27	.	.	PUNCT
bjp-19567	176	1	cancer	cancer	NOUN
bjp-19567	176	2	biol	biol	PROPN
bjp-19567	176	3	ther	ther	ADV
bjp-19567	176	4	.	.	PUNCT
bjp-19567	177	1	2008	2008	NUM
bjp-19567	177	2	;	;	PUNCT
bjp-19567	177	3	7	7	NUM
bjp-19567	177	4	:	:	SYM
bjp-19567	177	5	966	966	NUM
bjp-19567	177	6	-	-	SYM
bjp-19567	177	7	73	73	NUM
bjp-19567	177	8	.	.	PUNCT
bjp-19567	178	1	luo	luo	PROPN
bjp-19567	178	2	g	g	PROPN
bjp-19567	178	3	,	,	PUNCT
bjp-19567	178	4	zeng	zeng	PROPN
bjp-19567	178	5	y	y	PROPN
bjp-19567	178	6	,	,	PUNCT
bjp-19567	178	7	zhu	zhu	PROPN
bjp-19567	178	8	l	l	PROPN
bjp-19567	178	9	,	,	PUNCT
bjp-19567	178	10	zhang	zhang	PROPN
bjp-19567	178	11	yx	yx	PROPN
bjp-19567	178	12	,	,	PUNCT
bjp-19567	178	13	zhou	zhou	PROPN
bjp-19567	178	14	lm	lm	PROPN
bjp-19567	178	15	.	.	PROPN
bjp-19567	178	16	inhibition	inhibition	NOUN
bjp-19567	178	17	effect	effect	NOUN
bjp-19567	178	18	and	and	CCONJ
bjp-19567	178	19	its	its	PRON
bjp-19567	178	20	mechanism	mechanism	NOUN
bjp-19567	178	21	of	of	ADP
bjp-19567	178	22	nobiletin	nobiletin	NOUN
bjp-19567	178	23	on	on	ADP
bjp-19567	178	24	proliferation	proliferation	NOUN
bjp-19567	178	25	of	of	ADP
bjp-19567	178	26	lung	lung	NOUN
bjp-19567	178	27	cancer	cancer	NOUN
bjp-19567	178	28	cells	cell	NOUN
bjp-19567	178	29	.	.	PUNCT
bjp-19567	179	1	sichuan	sichuan	PROPN
bjp-19567	179	2	da	da	PROPN
bjp-19567	179	3	xue	xue	PROPN
bjp-19567	179	4	xue	xue	PROPN
bjp-19567	179	5	bao	bao	PROPN
bjp-19567	179	6	yi	yi	PROPN
bjp-19567	179	7	xue	xue	PROPN
bjp-19567	179	8	ban	ban	PROPN
bjp-19567	179	9	.	.	PUNCT
bjp-19567	180	1	2009	2009	NUM
bjp-19567	180	2	;	;	PUNCT
bjp-19567	180	3	40	40	NUM
bjp-19567	180	4	:	:	PUNCT
bjp-19567	180	5	449	449	NUM
bjp-19567	180	6	-	-	SYM
bjp-19567	180	7	53	53	NUM
bjp-19567	180	8	.	.	PUNCT
bjp-19567	181	1	ma	ma	PROPN
bjp-19567	181	2	x	x	PROPN
bjp-19567	181	3	,	,	PUNCT
bjp-19567	181	4	jin	jin	PROPN
bjp-19567	181	5	s	s	PROPN
bjp-19567	181	6	,	,	PUNCT
bjp-19567	181	7	zhang	zhang	PROPN
bjp-19567	181	8	y	y	PROPN
bjp-19567	181	9	,	,	PUNCT
bjp-19567	181	10	wan	wan	PROPN
bjp-19567	181	11	l	l	PROPN
bjp-19567	181	12	,	,	PUNCT
bjp-19567	181	13	zhao	zhao	PROPN
bjp-19567	181	14	y	y	PROPN
bjp-19567	181	15	,	,	PUNCT
bjp-19567	181	16	zhao	zhao	PROPN
bjp-19567	181	17	l.	l.	PROPN
bjp-19567	181	18	inhibitory	inhibitory	ADJ
bjp-19567	181	19	effects	effect	NOUN
bjp-19567	181	20	of	of	ADP
bjp-19567	181	21	nobiletin	nobiletin	NOUN
bjp-19567	181	22	on	on	ADP
bjp-19567	181	23	hepatocellular	hepatocellular	ADJ
bjp-19567	181	24	carcinoma	carcinoma	NOUN
bjp-19567	181	25	in	in	ADP
bjp-19567	181	26	vitro	vitro	X
bjp-19567	181	27	and	and	CCONJ
bjp-19567	181	28	in	in	ADP
bjp-19567	181	29	vivo	vivo	NOUN
bjp-19567	181	30	.	.	PUNCT
bjp-19567	182	1	phytother	phytother	PROPN
bjp-19567	182	2	res	re	NOUN
bjp-19567	182	3	.	.	PROPN
bjp-19567	182	4	2014	2014	NUM
bjp-19567	182	5	;	;	PUNCT
bjp-19567	182	6	28	28	NUM
bjp-19567	182	7	:	:	PUNCT
bjp-19567	182	8	560	560	NUM
bjp-19567	182	9	-	-	SYM
bjp-19567	182	10	67	67	NUM
bjp-19567	182	11	.	.	PUNCT
bjp-19567	183	1	murakami	murakami	PROPN
bjp-19567	183	2	a	a	PROPN
bjp-19567	183	3	,	,	PUNCT
bjp-19567	183	4	nakamura	nakamura	PROPN
bjp-19567	183	5	y	y	PROPN
bjp-19567	183	6	,	,	PUNCT
bjp-19567	183	7	torikai	torikai	PROPN
bjp-19567	183	8	k	k	PROPN
bjp-19567	183	9	,	,	PUNCT
bjp-19567	183	10	tanaka	tanaka	PROPN
bjp-19567	183	11	t	t	PROPN
bjp-19567	183	12	,	,	PUNCT
bjp-19567	183	13	koshiba	koshiba	PROPN
bjp-19567	183	14	t	t	PROPN
bjp-19567	183	15	,	,	PUNCT
bjp-19567	183	16	koshimizu	koshimizu	PROPN
bjp-19567	183	17	k	k	PROPN
bjp-19567	183	18	,	,	PUNCT
bjp-19567	183	19	kuwahara	kuwahara	PROPN
bjp-19567	183	20	s	s	PROPN
bjp-19567	183	21	,	,	PUNCT
bjp-19567	183	22	takahashi	takahashi	PROPN
bjp-19567	183	23	y	y	PROPN
bjp-19567	183	24	,	,	PUNCT
bjp-19567	183	25	ogawa	ogawa	PROPN
bjp-19567	183	26	k	k	PROPN
bjp-19567	183	27	,	,	PUNCT
bjp-19567	183	28	yano	yano	PROPN
bjp-19567	183	29	m	m	PROPN
bjp-19567	183	30	,	,	PUNCT
bjp-19567	183	31	tokuda	tokuda	PRON
bjp-19567	183	32	h	h	NOUN
bjp-19567	183	33	,	,	PUNCT
bjp-19567	183	34	nishino	nishino	PROPN
bjp-19567	183	35	h	h	PROPN
bjp-19567	183	36	,	,	PUNCT
bjp-19567	183	37	mimaki	mimaki	VERB
bjp-19567	183	38	y	y	PROPN
bjp-19567	183	39	,	,	PUNCT
bjp-19567	183	40	sashida	sashida	VERB
bjp-19567	183	41	y	y	PROPN
bjp-19567	183	42	,	,	PUNCT
bjp-19567	183	43	kitanaka	kitanaka	PROPN
bjp-19567	183	44	s	s	PROPN
bjp-19567	183	45	,	,	PUNCT
bjp-19567	183	46	ohigashi	ohigashi	PROPN
bjp-19567	183	47	h.	h.	PROPN
bjp-19567	183	48	inhibitory	inhibitory	ADJ
bjp-19567	183	49	effect	effect	NOUN
bjp-19567	183	50	of	of	ADP
bjp-19567	183	51	citrus	citrus	NOUN
bjp-19567	183	52	nobiletin	nobiletin	NOUN
bjp-19567	183	53	on	on	ADP
bjp-19567	183	54	phorbol	phorbol	NOUN
bjp-19567	183	55	ester	ester	NOUN
bjp-19567	183	56	-	-	PUNCT
bjp-19567	183	57	induced	induce	VERB
bjp-19567	183	58	skin	skin	NOUN
bjp-19567	183	59	inflammation	inflammation	NOUN
bjp-19567	183	60	,	,	PUNCT
bjp-19567	183	61	oxidative	oxidative	ADJ
bjp-19567	183	62	stress	stress	NOUN
bjp-19567	183	63	,	,	PUNCT
bjp-19567	183	64	and	and	CCONJ
bjp-19567	183	65	tumor	tumor	NOUN
bjp-19567	183	66	promotion	promotion	NOUN
bjp-19567	183	67	in	in	ADP
bjp-19567	183	68	mice	mouse	NOUN
bjp-19567	183	69	.	.	PUNCT
bjp-19567	184	1	cancer	cancer	NOUN
bjp-19567	184	2	res	re	NOUN
bjp-19567	184	3	.	.	PROPN
bjp-19567	184	4	2000	2000	NUM
bjp-19567	184	5	;	;	PUNCT
bjp-19567	184	6	60	60	NUM
bjp-19567	184	7	:	:	SYM
bjp-19567	184	8	5059	5059	NUM
bjp-19567	184	9	-	-	SYM
bjp-19567	184	10	66	66	NUM
bjp-19567	184	11	.	.	PUNCT
bjp-19567	185	1	murakami	murakami	PROPN
bjp-19567	185	2	a	a	PRON
bjp-19567	185	3	,	,	PUNCT
bjp-19567	185	4	shigemori	shigemori	PROPN
bjp-19567	185	5	t	t	PROPN
bjp-19567	185	6	,	,	PUNCT
bjp-19567	185	7	ohigashi	ohigashi	PROPN
bjp-19567	185	8	h.	h.	PROPN
bjp-19567	185	9	zingiberaceous	zingiberaceous	PROPN
bjp-19567	185	10	and	and	CCONJ
bjp-19567	185	11	citrus	citrus	ADJ
bjp-19567	185	12	constituents	constituent	NOUN
bjp-19567	185	13	,	,	PUNCT
bjp-19567	185	14	1′-cetoxychavicol	1′-cetoxychavicol	NUM
bjp-19567	185	15	acetate	acetate	NOUN
bjp-19567	185	16	,	,	PUNCT
bjp-19567	185	17	zerumbone	zerumbone	NOUN
bjp-19567	185	18	,	,	PUNCT
bjp-19567	185	19	auraptene	auraptene	NOUN
bjp-19567	185	20	,	,	PUNCT
bjp-19567	185	21	and	and	CCONJ
bjp-19567	185	22	nobiletin	nobiletin	NOUN
bjp-19567	185	23	,	,	PUNCT
bjp-19567	185	24	suppress	suppress	ADJ
bjp-19567	185	25	lipopolysaccharideinduced	lipopolysaccharideinduce	VERB
bjp-19567	185	26	cyclooxygenase-2	cyclooxygenase-2	NUM
bjp-19567	185	27	expression	expression	NOUN
bjp-19567	185	28	in	in	ADP
bjp-19567	185	29	raw264.7	raw264.7	PROPN
bjp-19567	185	30	murine	murine	ADJ
bjp-19567	185	31	macrophages	macrophage	NOUN
bjp-19567	185	32	through	through	ADP
bjp-19567	185	33	different	different	ADJ
bjp-19567	185	34	modes	mode	NOUN
bjp-19567	185	35	of	of	ADP
bjp-19567	185	36	action	action	NOUN
bjp-19567	185	37	.	.	PUNCT
bjp-19567	186	1	j	j	PROPN
bjp-19567	186	2	nutr	nutr	PROPN
bjp-19567	186	3	.	.	PROPN
bjp-19567	186	4	2005	2005	NUM
bjp-19567	186	5	;	;	PUNCT
bjp-19567	186	6	135	135	NUM
bjp-19567	186	7	:	:	SYM
bjp-19567	186	8	2987s-92s	2987s-92s	NUM
bjp-19567	186	9	.	.	PUNCT
bjp-19567	187	1	nakajima	nakajima	PROPN
bjp-19567	187	2	a	a	PROPN
bjp-19567	187	3	,	,	PUNCT
bjp-19567	187	4	yamakuni	yamakuni	PROPN
bjp-19567	187	5	t	t	PROPN
bjp-19567	187	6	,	,	PUNCT
bjp-19567	187	7	haraguchi	haraguchi	PROPN
bjp-19567	187	8	m	m	PROPN
bjp-19567	187	9	,	,	PUNCT
bjp-19567	187	10	omae	omae	PROPN
bjp-19567	187	11	n	n	CCONJ
bjp-19567	187	12	,	,	PUNCT
bjp-19567	187	13	song	song	NOUN
bjp-19567	187	14	sy	sy	PROPN
bjp-19567	187	15	,	,	PUNCT
bjp-19567	187	16	kato	kato	PROPN
bjp-19567	187	17	c	c	PROPN
bjp-19567	187	18	,	,	PUNCT
bjp-19567	187	19	nakagawasai	nakagawasai	PROPN
bjp-19567	187	20	o	o	NOUN
bjp-19567	187	21	,	,	PUNCT
bjp-19567	187	22	tadano	tadano	PROPN
bjp-19567	187	23	t	t	PROPN
bjp-19567	187	24	,	,	PUNCT
bjp-19567	187	25	yokosuka	yokosuka	PROPN
bjp-19567	187	26	a	a	PROPN
bjp-19567	187	27	,	,	PUNCT
bjp-19567	187	28	mimaki	mimaki	VERB
bjp-19567	187	29	y	y	PROPN
bjp-19567	187	30	,	,	PUNCT
bjp-19567	187	31	sashida	sashida	VERB
bjp-19567	187	32	y	y	PROPN
bjp-19567	187	33	,	,	PUNCT
bjp-19567	187	34	ohizumi	ohizumi	PROPN
bjp-19567	187	35	y.	y.	PROPN
bjp-19567	187	36	nobiletin	nobiletin	PROPN
bjp-19567	187	37	,	,	PUNCT
bjp-19567	187	38	a	a	DET
bjp-19567	187	39	citrus	citrus	NOUN
bjp-19567	187	40	flavonoid	flavonoid	NOUN
bjp-19567	187	41	that	that	PRON
bjp-19567	187	42	improves	improve	VERB
bjp-19567	187	43	memory	memory	NOUN
bjp-19567	187	44	impairment	impairment	NOUN
bjp-19567	187	45	,	,	PUNCT
bjp-19567	187	46	rescues	rescue	NOUN
bjp-19567	187	47	bulbectomyinduced	bulbectomyinduce	VERB
bjp-19567	187	48	cholinergic	cholinergic	ADJ
bjp-19567	187	49	neurodegeneration	neurodegeneration	NOUN
bjp-19567	187	50	in	in	ADP
bjp-19567	187	51	mice	mouse	NOUN
bjp-19567	187	52	.	.	PUNCT
bjp-19567	188	1	j	j	PROPN
bjp-19567	188	2	pharmacol	pharmacol	PROPN
bjp-19567	188	3	sci	sci	PROPN
bjp-19567	188	4	.	.	PROPN
bjp-19567	188	5	2007	2007	NUM
bjp-19567	188	6	;	;	PUNCT
bjp-19567	188	7	105	105	NUM
bjp-19567	188	8	:	:	SYM
bjp-19567	188	9	122	122	NUM
bjp-19567	188	10	-	-	SYM
bjp-19567	188	11	26	26	NUM
bjp-19567	188	12	.	.	PUNCT
bjp-19567	189	1	neuhouser	neuhouser	PROPN
bjp-19567	189	2	ml	ml	PROPN
bjp-19567	189	3	.	.	PUNCT
bjp-19567	190	1	dietary	dietary	ADJ
bjp-19567	190	2	flavonoids	flavonoid	NOUN
bjp-19567	190	3	and	and	CCONJ
bjp-19567	190	4	cancer	cancer	NOUN
bjp-19567	190	5	risk	risk	NOUN
bjp-19567	190	6	:	:	PUNCT
bjp-19567	190	7	evidence	evidence	NOUN
bjp-19567	190	8	from	from	ADP
bjp-19567	190	9	human	human	ADJ
bjp-19567	190	10	population	population	NOUN
bjp-19567	190	11	studies	study	NOUN
bjp-19567	190	12	.	.	PUNCT
bjp-19567	191	1	nutr	nutr	NOUN
bjp-19567	191	2	cancer	cancer	NOUN
bjp-19567	191	3	.	.	PUNCT
bjp-19567	192	1	2004	2004	NUM
bjp-19567	192	2	;	;	PUNCT
bjp-19567	192	3	50	50	NUM
bjp-19567	192	4	:	:	SYM
bjp-19567	192	5	1	1	NUM
bjp-19567	192	6	-	-	SYM
bjp-19567	192	7	7	7	NUM
bjp-19567	192	8	.	.	PUNCT
bjp-19567	193	1	newman	newman	PROPN
bjp-19567	193	2	dj	dj	PROPN
bjp-19567	193	3	,	,	PUNCT
bjp-19567	193	4	cragg	cragg	PROPN
bjp-19567	193	5	gm	gm	PROPN
bjp-19567	193	6	.	.	PUNCT
bjp-19567	193	7	natural	natural	ADJ
bjp-19567	193	8	products	product	NOUN
bjp-19567	193	9	as	as	ADP
bjp-19567	193	10	sources	source	NOUN
bjp-19567	193	11	of	of	ADP
bjp-19567	193	12	new	new	ADJ
bjp-19567	193	13	drugs	drug	NOUN
bjp-19567	193	14	over	over	ADP
bjp-19567	193	15	the	the	DET
bjp-19567	193	16	last	last	ADJ
bjp-19567	193	17	25	25	NUM
bjp-19567	193	18	years	year	NOUN
bjp-19567	193	19	.	.	PUNCT
bjp-19567	194	1	j	j	PROPN
bjp-19567	194	2	nat	nat	PROPN
bjp-19567	194	3	prod	prod	NOUN
bjp-19567	194	4	.	.	PUNCT
bjp-19567	195	1	2007	2007	NUM
bjp-19567	195	2	;	;	PUNCT
bjp-19567	195	3	70	70	NUM
bjp-19567	195	4	:	:	PUNCT
bjp-19567	195	5	461	461	NUM
bjp-19567	195	6	-	-	SYM
bjp-19567	195	7	77	77	NUM
bjp-19567	195	8	.	.	PUNCT
bjp-19567	196	1	park	park	NOUN
bjp-19567	196	2	hh	hh	PROPN
bjp-19567	196	3	.	.	PROPN
bjp-19567	197	1	structural	structural	ADJ
bjp-19567	197	2	features	feature	NOUN
bjp-19567	197	3	of	of	ADP
bjp-19567	197	4	caspase	caspase	NOUN
bjp-19567	197	5	-	-	PUNCT
bjp-19567	197	6	activating	activate	VERB
bjp-19567	197	7	complexes	complex	NOUN
bjp-19567	197	8	.	.	PUNCT
bjp-19567	198	1	int	int	PROPN
bjp-19567	198	2	j	j	PROPN
bjp-19567	198	3	mol	mol	ADP
bjp-19567	198	4	sci	sci	PROPN
bjp-19567	198	5	.	.	PROPN
bjp-19567	198	6	2012	2012	NUM
bjp-19567	198	7	;	;	PUNCT
bjp-19567	198	8	13	13	NUM
bjp-19567	198	9	:	:	SYM
bjp-19567	198	10	4807	4807	NUM
bjp-19567	198	11	-	-	SYM
bjp-19567	198	12	18	18	NUM
bjp-19567	198	13	.	.	PUNCT
bjp-19567	199	1	sato	sato	PROPN
bjp-19567	199	2	t	t	PROPN
bjp-19567	199	3	,	,	PUNCT
bjp-19567	199	4	koike	koike	PROPN
bjp-19567	199	5	l	l	PROPN
bjp-19567	199	6	,	,	PUNCT
bjp-19567	199	7	miyata	miyata	PROPN
bjp-19567	199	8	y	y	PROPN
bjp-19567	199	9	,	,	PUNCT
bjp-19567	199	10	hirata	hirata	NOUN
bjp-19567	199	11	m	m	PROPN
bjp-19567	199	12	,	,	PUNCT
bjp-19567	199	13	mimaki	mimaki	VERB
bjp-19567	199	14	y	y	PROPN
bjp-19567	199	15	,	,	PUNCT
bjp-19567	199	16	sashida	sashida	VERB
bjp-19567	199	17	y	y	PROPN
bjp-19567	199	18	,	,	PUNCT
bjp-19567	199	19	yano	yano	PROPN
bjp-19567	199	20	m	m	PROPN
bjp-19567	199	21	,	,	PUNCT
bjp-19567	199	22	ito	ito	PROPN
bjp-19567	199	23	a.	a.	NOUN
bjp-19567	199	24	inhibition	inhibition	NOUN
bjp-19567	199	25	of	of	ADP
bjp-19567	199	26	activator	activator	NOUN
bjp-19567	199	27	protein-1	protein-1	NUM
bjp-19567	199	28	binding	bind	VERB
bjp-19567	199	29	activity	activity	NOUN
bjp-19567	199	30	and	and	CCONJ
bjp-19567	199	31	phosphatidylinositol	phosphatidylinositol	NOUN
bjp-19567	199	32	3	3	NUM
bjp-19567	199	33	-	-	PUNCT
bjp-19567	199	34	hinase	hinase	NOUN
bjp-19567	199	35	pathway	pathway	NOUN
bjp-19567	199	36	by	by	ADP
bjp-19567	199	37	nobiletin	nobiletin	NOUN
bjp-19567	199	38	,	,	PUNCT
bjp-19567	199	39	a	a	DET
bjp-19567	199	40	polymethoxy	polymethoxy	ADJ
bjp-19567	199	41	flavonoid	flavonoid	NOUN
bjp-19567	199	42	,	,	PUNCT
bjp-19567	199	43	results	result	VERB
bjp-19567	199	44	in	in	ADP
bjp-19567	199	45	augmentation	augmentation	NOUN
bjp-19567	199	46	of	of	ADP
bjp-19567	199	47	tissue	tissue	NOUN
bjp-19567	199	48	inhibitor	inhibitor	NOUN
bjp-19567	199	49	of	of	ADP
bjp-19567	199	50	metalloproteinases-1	metalloproteinases-1	NUM
bjp-19567	199	51	production	production	NOUN
bjp-19567	199	52	and	and	CCONJ
bjp-19567	199	53	suppression	suppression	NOUN
bjp-19567	199	54	of	of	ADP
bjp-19567	199	55	production	production	NOUN
bjp-19567	199	56	of	of	ADP
bjp-19567	199	57	matrix	matrix	NOUN
bjp-19567	199	58	metalloproteinases-1	metalloproteinases-1	NUM
bjp-19567	199	59	and	and	CCONJ
bjp-19567	199	60	-9	-9	PROPN
bjp-19567	199	61	in	in	ADP
bjp-19567	199	62	human	human	ADJ
bjp-19567	199	63	fibrosarcoma	fibrosarcoma	ADJ
bjp-19567	199	64	ht-1080	ht-1080	NOUN
bjp-19567	199	65	cells	cell	NOUN
bjp-19567	199	66	.	.	PUNCT
bjp-19567	200	1	cancer	cancer	NOUN
bjp-19567	200	2	res	re	NOUN
bjp-19567	200	3	.	.	PUNCT
bjp-19567	200	4	2002	2002	NUM
bjp-19567	200	5	;	;	PUNCT
bjp-19567	200	6	62	62	NUM
bjp-19567	200	7	:	:	PUNCT
bjp-19567	200	8	1025	1025	NUM
bjp-19567	200	9	-	-	SYM
bjp-19567	200	10	29	29	NUM
bjp-19567	200	11	.	.	PUNCT
bjp-19567	201	1	shi	shi	PROPN
bjp-19567	201	2	md	md	PROPN
bjp-19567	201	3	,	,	PUNCT
bjp-19567	201	4	liao	liao	PROPN
bjp-19567	201	5	yc	yc	PROPN
bjp-19567	201	6	,	,	PUNCT
bjp-19567	201	7	shih	shih	PROPN
bjp-19567	201	8	yw	yw	PROPN
bjp-19567	201	9	,	,	PUNCT
bjp-19567	201	10	tsai	tsai	PROPN
bjp-19567	201	11	ly	ly	PROPN
bjp-19567	201	12	.	.	PUNCT
bjp-19567	201	13	nobiletin	nobiletin	NOUN
bjp-19567	201	14	attenuates	attenuate	VERB
bjp-19567	201	15	metastasis	metastasis	NOUN
bjp-19567	201	16	via	via	ADP
bjp-19567	201	17	both	both	CCONJ
bjp-19567	201	18	erk	erk	PROPN
bjp-19567	201	19	and	and	CCONJ
bjp-19567	201	20	pi3k	pi3k	PROPN
bjp-19567	201	21	/	/	SYM
bjp-19567	201	22	akt	akt	PROPN
bjp-19567	201	23	pathways	pathway	NOUN
bjp-19567	201	24	in	in	ADP
bjp-19567	201	25	hgftreated	hgftreated	ADJ
bjp-19567	201	26	liver	liver	NOUN
bjp-19567	201	27	cancer	cancer	NOUN
bjp-19567	201	28	hepg2	hepg2	PUNCT
bjp-19567	201	29	cells	cell	NOUN
bjp-19567	201	30	.	.	PUNCT
bjp-19567	202	1	phytomedicine	phytomedicine	PROPN
bjp-19567	202	2	2013	2013	NUM
bjp-19567	202	3	;	;	PUNCT
bjp-19567	202	4	20	20	NUM
bjp-19567	202	5	:	:	SYM
bjp-19567	202	6	743	743	NUM
bjp-19567	202	7	-	-	SYM
bjp-19567	202	8	52	52	NUM
bjp-19567	202	9	.	.	PUNCT
bjp-19567	203	1	tang	tang	PROPN
bjp-19567	203	2	m	m	PROPN
bjp-19567	203	3	,	,	PUNCT
bjp-19567	203	4	ogawa	ogawa	PROPN
bjp-19567	203	5	k	k	PROPN
bjp-19567	203	6	,	,	PUNCT
bjp-19567	203	7	asamoto	asamoto	PROPN
bjp-19567	203	8	m	m	PROPN
bjp-19567	203	9	,	,	PUNCT
bjp-19567	203	10	hokaiwado	hokaiwado	PROPN
bjp-19567	203	11	n	n	CCONJ
bjp-19567	203	12	,	,	PUNCT
bjp-19567	203	13	seeni	seeni	NOUN
bjp-19567	203	14	a	a	PRON
bjp-19567	203	15	,	,	PUNCT
bjp-19567	203	16	suzuki	suzuki	PROPN
bjp-19567	203	17	s	s	PROPN
bjp-19567	203	18	,	,	PUNCT
bjp-19567	203	19	takahashi	takahashi	PROPN
bjp-19567	203	20	s	s	PROPN
bjp-19567	203	21	,	,	PUNCT
bjp-19567	203	22	tanaka	tanaka	PROPN
bjp-19567	203	23	t	t	PROPN
bjp-19567	203	24	,	,	PUNCT
bjp-19567	203	25	ichikawa	ichikawa	PROPN
bjp-19567	203	26	k	k	PROPN
bjp-19567	203	27	,	,	PUNCT
bjp-19567	203	28	shirai	shirai	ADJ
bjp-19567	203	29	t.	t.	ADJ
bjp-19567	203	30	protective	protective	ADJ
bjp-19567	203	31	effects	effect	NOUN
bjp-19567	203	32	of	of	ADP
bjp-19567	203	33	citrus	citrus	NOUN
bjp-19567	203	34	nobiletin	nobiletin	NOUN
bjp-19567	203	35	and	and	CCONJ
bjp-19567	203	36	auraptene	auraptene	NOUN
bjp-19567	203	37	in	in	ADP
bjp-19567	203	38	transgenic	transgenic	NOUN
bjp-19567	203	39	rats	rat	NOUN
bjp-19567	203	40	developing	develop	VERB
bjp-19567	203	41	adenocarcinoma	adenocarcinoma	NOUN
bjp-19567	203	42	of	of	ADP
bjp-19567	203	43	the	the	DET
bjp-19567	203	44	prostate	prostate	NOUN
bjp-19567	203	45	(	(	PUNCT
bjp-19567	203	46	trap	trap	NOUN
bjp-19567	203	47	)	)	PUNCT
bjp-19567	203	48	and	and	CCONJ
bjp-19567	203	49	human	human	ADJ
bjp-19567	203	50	prostate	prostate	NOUN
bjp-19567	203	51	carcinoma	carcinoma	NOUN
bjp-19567	203	52	cells	cell	NOUN
bjp-19567	203	53	.	.	PUNCT
bjp-19567	204	1	cancer	cancer	PROPN
bjp-19567	204	2	sci	sci	PROPN
bjp-19567	204	3	.	.	PROPN
bjp-19567	204	4	2007	2007	NUM
bjp-19567	204	5	;	;	PUNCT
bjp-19567	204	6	98	98	NUM
bjp-19567	204	7	:	:	PUNCT
bjp-19567	204	8	471	471	NUM
bjp-19567	204	9	-	-	SYM
bjp-19567	204	10	77	77	NUM
bjp-19567	204	11	.	.	PUNCT
bjp-19567	205	1	wu	wu	PROPN
bjp-19567	205	2	jj	jj	PROPN
bjp-19567	205	3	,	,	PUNCT
bjp-19567	205	4	cui	cui	PROPN
bjp-19567	205	5	y	y	PROPN
bjp-19567	205	6	,	,	PUNCT
bjp-19567	205	7	yang	yang	PROPN
bjp-19567	205	8	ys	ys	PROPN
bjp-19567	205	9	,	,	PUNCT
bjp-19567	205	10	jung	jung	PROPN
bjp-19567	205	11	sc	sc	PROPN
bjp-19567	205	12	,	,	PUNCT
bjp-19567	205	13	hyun	hyun	PROPN
bjp-19567	205	14	jw	jw	PROPN
bjp-19567	205	15	,	,	PUNCT
bjp-19567	205	16	maeng	maeng	PROPN
bjp-19567	205	17	yh	yh	PROPN
bjp-19567	205	18	,	,	PUNCT
bjp-19567	205	19	park	park	PROPN
bjp-19567	205	20	db	db	PROPN
bjp-19567	205	21	,	,	PUNCT
bjp-19567	205	22	lee	lee	PROPN
bjp-19567	205	23	sr	sr	PROPN
bjp-19567	205	24	,	,	PUNCT
bjp-19567	205	25	kim	kim	PROPN
bjp-19567	205	26	sj	sj	PROPN
bjp-19567	205	27	,	,	PUNCT
bjp-19567	205	28	eun	eun	PROPN
bjp-19567	205	29	sy	sy	PROPN
bjp-19567	205	30	.	.	PUNCT
bjp-19567	206	1	mild	mild	ADJ
bjp-19567	206	2	mitochondrial	mitochondrial	ADJ
bjp-19567	206	3	depolarization	depolarization	NOUN
bjp-19567	206	4	is	be	AUX
bjp-19567	206	5	involved	involve	VERB
bjp-19567	206	6	in	in	ADP
bjp-19567	206	7	a	a	DET
bjp-19567	206	8	neuroprotective	neuroprotective	ADJ
bjp-19567	206	9	mechanism	mechanism	NOUN
bjp-19567	206	10	of	of	ADP
bjp-19567	206	11	citrus	citrus	NOUN
bjp-19567	206	12	sunki	sunki	PROPN
bjp-19567	206	13	peel	peel	NOUN
bjp-19567	206	14	extract	extract	NOUN
bjp-19567	206	15	.	.	PUNCT
bjp-19567	207	1	phytother	phytother	PROPN
bjp-19567	207	2	res	re	NOUN
bjp-19567	207	3	.	.	PUNCT
bjp-19567	207	4	2013	2013	NUM
bjp-19567	207	5	;	;	PUNCT
bjp-19567	207	6	27	27	NUM
bjp-19567	207	7	:	:	PUNCT
bjp-19567	207	8	564	564	NUM
bjp-19567	207	9	-	-	SYM
bjp-19567	207	10	71	71	NUM
bjp-19567	207	11	.	.	PUNCT
bjp-19567	208	1	412	412	NUM
bjp-19567	208	2	bangladesh	bangladesh	NOUN
bjp-19567	208	3	j	j	PROPN
bjp-19567	208	4	pharmacol	pharmacol	PROPN
bjp-19567	208	5	2014	2014	NUM
bjp-19567	208	6	;	;	PUNCT
bjp-19567	208	7	9	9	NUM
bjp-19567	208	8	:	:	SYM
bjp-19567	208	9	406	406	NUM
bjp-19567	208	10	-	-	SYM
bjp-19567	208	11	412	412	NUM
bjp-19567	208	12	author	author	NOUN
bjp-19567	208	13	info	info	NOUN
bjp-19567	208	14	mao	mao	PROPN
bjp-19567	208	15	shu	shu	PROPN
bjp-19567	208	16	zhang	zhang	PROPN
bjp-19567	208	17	(	(	PUNCT
bjp-19567	208	18	principal	principal	ADJ
bjp-19567	208	19	contact	contact	NOUN
bjp-19567	208	20	)	)	PUNCT
bjp-19567	209	1	e	e	NOUN
bjp-19567	209	2	-	-	NOUN
bjp-19567	209	3	mail	mail	NOUN
bjp-19567	209	4	:	:	PUNCT
bjp-19567	209	5	mszhang475@hotmail.com	mszhang475@hotmail.com	X
bjp-19567	209	6	acknowledgement	acknowledgement	NOUN
bjp-19567	209	7	:	:	PUNCT
bjp-19567	209	8	references	reference	NOUN
bjp-19567	209	9	:	:	PUNCT
bjp-19567	209	10	m	m	VERB
bjp-19567	209	11	tokuda	tokuda	ADJ
bjp-19567	209	12	h	h	PROPN
bjp-19567	210	1	nishino	nishino	PROPN
bjp-19567	210	2	hmimaki	hmimaki	PROPN
bjp-19567	210	3	y	y	PROPN
bjp-19567	210	4	sashida	sashida	VERB
bjp-19567	210	5	y	y	PROPN
bjp-19567	210	6	kitanaka	kitanaka	PROPN
bjp-19567	210	7	:	:	PUNCT
bjp-19567	210	8	author	author	NOUN
bjp-19567	210	9	info	info	PROPN
bjp-19567	210	10	mao	mao	PROPN
bjp-19567	210	11	shu	shu	PROPN
bjp-19567	210	12	zhang	zhang	PROPN
bjp-19567	210	13	principal	principal	PROPN
bjp-19567	210	14	contact	contact	PROPN
bjp-19567	210	15	email	email	NOUN
bjp-19567	210	16	mszhang475hotmailcom	mszhang475hotmailcom	PROPN
bjp-19567	210	17	:	:	PUNCT
bjp-19567	210	18	dateprinted	dateprinte	VERB
bjp-19567	210	19	:	:	PUNCT
bjp-19567	210	20	this	this	DET
bjp-19567	210	21	article	article	NOUN
bjp-19567	210	22	was	be	AUX
bjp-19567	210	23	downloaded	download	VERB
bjp-19567	210	24	by	by	ADP
bjp-19567	210	25	you	you	PRON
bjp-19567	210	26	on	on	ADP
bjp-19567	210	27	:	:	PUNCT
bjp-19567	210	28	jul	jul	PROPN
bjp-19567	210	29	31	31	NUM
bjp-19567	210	30	,	,	PUNCT
bjp-19567	210	31	2018	2018	NUM