id	sid	tid	token	lemma	pos
bjp-22865	1	1	introduction	introduction	NOUN
bjp-22865	1	2	rheumatoid	rheumatoid	NOUN
bjp-22865	1	3	arthritis	arthritis	NOUN
bjp-22865	1	4	(	(	PUNCT
bjp-22865	1	5	ra	ra	NOUN
bjp-22865	1	6	)	)	PUNCT
bjp-22865	1	7	is	be	AUX
bjp-22865	1	8	a	a	DET
bjp-22865	1	9	chronic	chronic	ADJ
bjp-22865	1	10	inflammatory	inflammatory	ADJ
bjp-22865	1	11	systemic	systemic	ADJ
bjp-22865	1	12	disease	disease	NOUN
bjp-22865	1	13	of	of	ADP
bjp-22865	1	14	unknown	unknown	ADJ
bjp-22865	1	15	etiology	etiology	NOUN
bjp-22865	1	16	.	.	PUNCT
bjp-22865	2	1	it	it	PRON
bjp-22865	2	2	is	be	AUX
bjp-22865	2	3	characterized	characterize	VERB
bjp-22865	2	4	by	by	ADP
bjp-22865	2	5	high	high	ADJ
bjp-22865	2	6	infiltration	infiltration	NOUN
bjp-22865	2	7	of	of	ADP
bjp-22865	2	8	leukocytes	leukocyte	NOUN
bjp-22865	2	9	into	into	ADP
bjp-22865	2	10	the	the	DET
bjp-22865	2	11	synovium	synovium	NOUN
bjp-22865	2	12	,	,	PUNCT
bjp-22865	2	13	leading	lead	VERB
bjp-22865	2	14	to	to	ADP
bjp-22865	2	15	hyperplasia	hyperplasia	NOUN
bjp-22865	2	16	of	of	ADP
bjp-22865	2	17	the	the	DET
bjp-22865	2	18	synovial	synovial	ADJ
bjp-22865	2	19	lining	lining	NOUN
bjp-22865	2	20	,	,	PUNCT
bjp-22865	2	21	which	which	PRON
bjp-22865	2	22	causes	cause	VERB
bjp-22865	2	23	progressive	progressive	ADJ
bjp-22865	2	24	destruction	destruction	NOUN
bjp-22865	2	25	of	of	ADP
bjp-22865	2	26	the	the	DET
bjp-22865	2	27	cartilage	cartilage	NOUN
bjp-22865	2	28	consequently	consequently	ADV
bjp-22865	2	29	resulting	result	VERB
bjp-22865	2	30	in	in	ADP
bjp-22865	2	31	erosion	erosion	NOUN
bjp-22865	2	32	of	of	ADP
bjp-22865	2	33	the	the	DET
bjp-22865	2	34	underlying	underlie	VERB
bjp-22865	2	35	bone	bone	NOUN
bjp-22865	2	36	(	(	PUNCT
bjp-22865	2	37	pope	pope	NOUN
bjp-22865	2	38	,	,	PUNCT
bjp-22865	2	39	2002	2002	NUM
bjp-22865	2	40	)	)	PUNCT
bjp-22865	2	41	.	.	PUNCT
bjp-22865	3	1	the	the	DET
bjp-22865	3	2	activated	activate	VERB
bjp-22865	3	3	rheumatoid	rheumatoid	NOUN
bjp-22865	3	4	synovial	synovial	ADJ
bjp-22865	3	5	fibroblasts	fibroblast	NOUN
bjp-22865	3	6	(	(	PUNCT
bjp-22865	3	7	rasfs	rasfs	PROPN
bjp-22865	3	8	)	)	PUNCT
bjp-22865	3	9	aggressively	aggressively	ADV
bjp-22865	3	10	participate	participate	VERB
bjp-22865	3	11	in	in	ADP
bjp-22865	3	12	ra	ra	PROPN
bjp-22865	3	13	synovitis	synovitis	PROPN
bjp-22865	3	14	.	.	PUNCT
bjp-22865	4	1	rasfs	rasfs	PROPN
bjp-22865	4	2	in	in	ADP
bjp-22865	4	3	ra	ra	PROPN
bjp-22865	4	4	joints	joint	NOUN
bjp-22865	4	5	vigorously	vigorously	ADV
bjp-22865	4	6	proliferate	proliferate	VERB
bjp-22865	4	7	forming	form	VERB
bjp-22865	4	8	a	a	DET
bjp-22865	4	9	pannus	pannus	NOUN
bjp-22865	4	10	,	,	PUNCT
bjp-22865	4	11	which	which	PRON
bjp-22865	4	12	produce	produce	VERB
bjp-22865	4	13	inflammatory	inflammatory	ADJ
bjp-22865	4	14	mediators	mediator	NOUN
bjp-22865	4	15	such	such	ADJ
bjp-22865	4	16	as	as	ADP
bjp-22865	4	17	cytokines	cytokine	NOUN
bjp-22865	4	18	,	,	PUNCT
bjp-22865	4	19	matrix	matrix	NOUN
bjp-22865	4	20	metalloproteinases	metalloproteinase	NOUN
bjp-22865	4	21	(	(	PUNCT
bjp-22865	4	22	mmps	mmp	NOUN
bjp-22865	4	23	)	)	PUNCT
bjp-22865	4	24	,	,	PUNCT
bjp-22865	4	25	and	and	CCONJ
bjp-22865	4	26	cyclooxygenase-2	cyclooxygenase-2	NUM
bjp-22865	4	27	(	(	PUNCT
bjp-22865	4	28	cox-2	cox-2	NOUN
bjp-22865	4	29	)	)	PUNCT
bjp-22865	4	30	eventually	eventually	ADV
bjp-22865	4	31	leading	lead	VERB
bjp-22865	4	32	to	to	ADP
bjp-22865	4	33	the	the	DET
bjp-22865	4	34	destruction	destruction	NOUN
bjp-22865	4	35	of	of	ADP
bjp-22865	4	36	articular	articular	ADJ
bjp-22865	4	37	bone	bone	NOUN
bjp-22865	4	38	and	and	CCONJ
bjp-22865	4	39	cartilage	cartilage	NOUN
bjp-22865	4	40	(	(	PUNCT
bjp-22865	4	41	cawston	cawston	NOUN
bjp-22865	4	42	,	,	PUNCT
bjp-22865	4	43	1995	1995	NUM
bjp-22865	4	44	;	;	PUNCT
bjp-22865	4	45	han	han	PROPN
bjp-22865	4	46	et	et	PROPN
bjp-22865	4	47	al	al	PROPN
bjp-22865	4	48	.	.	PROPN
bjp-22865	4	49	,	,	PUNCT
bjp-22865	4	50	2003	2003	NUM
bjp-22865	4	51	)	)	PUNCT
bjp-22865	4	52	.	.	PUNCT
bjp-22865	5	1	interleukin	interleukin	NOUN
bjp-22865	5	2	1	1	NUM
bjp-22865	5	3	(	(	PUNCT
bjp-22865	5	4	il-1	il-1	X
bjp-22865	5	5	)	)	PUNCT
bjp-22865	5	6	is	be	AUX
bjp-22865	5	7	considered	consider	VERB
bjp-22865	5	8	as	as	ADP
bjp-22865	5	9	the	the	DET
bjp-22865	5	10	most	most	ADV
bjp-22865	5	11	important	important	ADJ
bjp-22865	5	12	cytokine	cytokine	NOUN
bjp-22865	5	13	in	in	ADP
bjp-22865	5	14	the	the	DET
bjp-22865	5	15	pathogenesis	pathogenesis	NOUN
bjp-22865	5	16	of	of	ADP
bjp-22865	5	17	inflammatory	inflammatory	ADJ
bjp-22865	5	18	events	event	NOUN
bjp-22865	5	19	in	in	ADP
bjp-22865	5	20	ra	ra	PROPN
bjp-22865	5	21	.	.	PUNCT
bjp-22865	5	22	il-1	il-1	PUNCT
bjp-22865	5	23	induces	induce	VERB
bjp-22865	5	24	the	the	DET
bjp-22865	5	25	proliferation	proliferation	NOUN
bjp-22865	5	26	of	of	ADP
bjp-22865	5	27	rasfs	rasfs	ADJ
bjp-22865	5	28	and	and	CCONJ
bjp-22865	5	29	also	also	ADV
bjp-22865	5	30	causes	cause	VERB
bjp-22865	5	31	the	the	DET
bjp-22865	5	32	production	production	NOUN
bjp-22865	5	33	of	of	ADP
bjp-22865	5	34	high	high	ADJ
bjp-22865	5	35	levels	level	NOUN
bjp-22865	5	36	of	of	ADP
bjp-22865	5	37	inflammatory	inflammatory	ADJ
bjp-22865	5	38	mediatorsmmps	mediatorsmmp	NOUN
bjp-22865	5	39	and	and	CCONJ
bjp-22865	5	40	prostaglandin	prostaglandin	NOUN
bjp-22865	5	41	e2	e2	PROPN
bjp-22865	5	42	(	(	PUNCT
bjp-22865	5	43	pge2	pge2	PROPN
bjp-22865	5	44	)	)	PUNCT
bjp-22865	5	45	(	(	PUNCT
bjp-22865	5	46	choy	choy	NOUN
bjp-22865	5	47	and	and	CCONJ
bjp-22865	5	48	panayi	panayi	NOUN
bjp-22865	5	49	,	,	PUNCT
bjp-22865	5	50	2001	2001	NUM
bjp-22865	5	51	)	)	PUNCT
bjp-22865	5	52	.	.	PUNCT
bjp-22865	6	1	while	while	SCONJ
bjp-22865	6	2	the	the	DET
bjp-22865	6	3	pathogenesis	pathogenesis	NOUN
bjp-22865	6	4	of	of	ADP
bjp-22865	6	5	ra	ra	PROPN
bjp-22865	6	6	is	be	AUX
bjp-22865	6	7	not	not	PART
bjp-22865	6	8	completely	completely	ADV
bjp-22865	6	9	understood	understand	VERB
bjp-22865	6	10	,	,	PUNCT
bjp-22865	6	11	the	the	DET
bjp-22865	6	12	process	process	NOUN
bjp-22865	6	13	is	be	AUX
bjp-22865	6	14	reported	report	VERB
bjp-22865	6	15	to	to	PART
bjp-22865	6	16	involve	involve	VERB
bjp-22865	6	17	cellular	cellular	ADJ
bjp-22865	6	18	infiltration	infiltration	NOUN
bjp-22865	6	19	into	into	ADP
bjp-22865	6	20	the	the	DET
bjp-22865	6	21	synovial	synovial	ADJ
bjp-22865	6	22	tissue	tissue	NOUN
bjp-22865	6	23	with	with	ADP
bjp-22865	6	24	marked	marked	ADJ
bjp-22865	6	25	increase	increase	NOUN
bjp-22865	6	26	of	of	ADP
bjp-22865	6	27	inflammatory	inflammatory	ADJ
bjp-22865	6	28	cytokines	cytokine	NOUN
bjp-22865	6	29	tumor	tumor	NOUN
bjp-22865	6	30	necrosis	necrosis	NOUN
bjp-22865	6	31	factor(tnf	factor(tnf	PROPN
bjp-22865	6	32	)	)	PUNCT
bjp-22865	6	33	,	,	PUNCT
bjp-22865	6	34	interleukin(il)-1	interleukin(il)-1	PROPN
bjp-22865	6	35	and	and	CCONJ
bjp-22865	6	36	il6	il6	PROPN
bjp-22865	6	37	,	,	PUNCT
bjp-22865	6	38	that	that	PRON
bjp-22865	6	39	eventually	eventually	ADV
bjp-22865	6	40	contribute	contribute	VERB
bjp-22865	6	41	to	to	ADP
bjp-22865	6	42	cartilage	cartilage	NOUN
bjp-22865	6	43	and	and	CCONJ
bjp-22865	6	44	bone	bone	NOUN
bjp-22865	6	45	erosion	erosion	NOUN
bjp-22865	6	46	(	(	PUNCT
bjp-22865	6	47	arend	arend	PROPN
bjp-22865	6	48	,	,	PUNCT
bjp-22865	6	49	2001	2001	NUM
bjp-22865	6	50	;	;	PUNCT
bjp-22865	6	51	choy	choy	NOUN
bjp-22865	6	52	,	,	PUNCT
bjp-22865	6	53	2012	2012	NUM
bjp-22865	6	54	)	)	PUNCT
bjp-22865	6	55	.	.	PUNCT
bjp-22865	7	1	these	these	DET
bjp-22865	7	2	mediators	mediator	NOUN
bjp-22865	7	3	activate	activate	VERB
bjp-22865	7	4	major	major	ADJ
bjp-22865	7	5	signalling	signal	VERB
bjp-22865	7	6	pathways	pathway	NOUN
bjp-22865	7	7	such	such	ADJ
bjp-22865	7	8	as	as	ADP
bjp-22865	7	9	the	the	DET
bjp-22865	7	10	nuclear	nuclear	ADJ
bjp-22865	7	11	factor	factor	NOUN
bjp-22865	7	12	(	(	PUNCT
bjp-22865	7	13	nf)-κb	nf)-κb	NOUN
bjp-22865	7	14	and	and	CCONJ
bjp-22865	7	15	mitogen	mitogen	NOUN
bjp-22865	7	16	activated	activate	VERB
bjp-22865	7	17	protein	protein	NOUN
bjp-22865	7	18	kinases	kinase	NOUN
bjp-22865	7	19	(	(	PUNCT
bjp-22865	7	20	mapks	mapks	NOUN
bjp-22865	7	21	)	)	PUNCT
bjp-22865	7	22	(	(	PUNCT
bjp-22865	7	23	tas	tas	X
bjp-22865	7	24	et	et	NOUN
bjp-22865	7	25	al	al	PROPN
bjp-22865	7	26	.	.	PROPN
bjp-22865	7	27	,	,	PUNCT
bjp-22865	7	28	2005	2005	NUM
bjp-22865	7	29	)	)	PUNCT
bjp-22865	7	30	.	.	PUNCT
bjp-22865	8	1	mapks	mapks	NOUN
bjp-22865	8	2	are	be	AUX
bjp-22865	8	3	a	a	DET
bjp-22865	8	4	family	family	NOUN
bjp-22865	8	5	of	of	ADP
bjp-22865	8	6	serine	serine	NOUN
bjp-22865	8	7	/	/	SYM
bjp-22865	8	8	threonine	threonine	ADJ
bjp-22865	8	9	kinases	kinase	NOUN
bjp-22865	8	10	that	that	PRON
bjp-22865	8	11	are	be	AUX
bjp-22865	8	12	involved	involve	VERB
bjp-22865	8	13	in	in	ADP
bjp-22865	8	14	various	various	ADJ
bjp-22865	8	15	cellular	cellular	ADJ
bjp-22865	8	16	events	event	NOUN
bjp-22865	8	17	such	such	ADJ
bjp-22865	8	18	as	as	ADP
bjp-22865	8	19	inflammation	inflammation	NOUN
bjp-22865	8	20	,	,	PUNCT
bjp-22865	8	21	transcription	transcription	NOUN
bjp-22865	8	22	of	of	ADP
bjp-22865	8	23	pro	pro	ADJ
bjp-22865	8	24	-	-	ADJ
bjp-22865	8	25	inflammatory	inflammatory	ADJ
bjp-22865	8	26	factors	factor	NOUN
bjp-22865	8	27	and	and	CCONJ
bjp-22865	8	28	a	a	DET
bjp-22865	8	29	journal	journal	NOUN
bjp-22865	8	30	of	of	ADP
bjp-22865	8	31	the	the	DET
bjp-22865	8	32	bangladesh	bangladesh	NOUN
bjp-22865	8	33	pharmacological	pharmacological	ADJ
bjp-22865	8	34	society	society	NOUN
bjp-22865	8	35	(	(	PUNCT
bjp-22865	8	36	bdps	bdps	NOUN
bjp-22865	8	37	)	)	PUNCT
bjp-22865	8	38	bangladesh	bangladesh	PROPN
bjp-22865	8	39	j	j	PROPN
bjp-22865	8	40	pharmacol	pharmacol	PROPN
bjp-22865	8	41	2015	2015	NUM
bjp-22865	8	42	;	;	PUNCT
bjp-22865	8	43	10	10	NUM
bjp-22865	8	44	:	:	SYM
bjp-22865	8	45	714	714	NUM
bjp-22865	8	46	-	-	SYM
bjp-22865	8	47	725	725	NUM
bjp-22865	8	48	journal	journal	NOUN
bjp-22865	8	49	homepage	homepage	NOUN
bjp-22865	8	50	:	:	PUNCT
bjp-22865	8	51	www.banglajol.info	www.banglajol.info	PROPN
bjp-22865	8	52	abstracted	abstract	VERB
bjp-22865	8	53	/	/	SYM
bjp-22865	8	54	indexed	index	VERB
bjp-22865	8	55	in	in	ADP
bjp-22865	8	56	academic	academic	ADJ
bjp-22865	8	57	search	search	NOUN
bjp-22865	8	58	complete	complete	ADJ
bjp-22865	8	59	,	,	PUNCT
bjp-22865	8	60	agroforestry	agroforestry	NOUN
bjp-22865	8	61	abstracts	abstract	NOUN
bjp-22865	8	62	,	,	PUNCT
bjp-22865	8	63	asia	asia	PROPN
bjp-22865	8	64	journals	journal	NOUN
bjp-22865	8	65	online	online	ADV
bjp-22865	8	66	,	,	PUNCT
bjp-22865	8	67	bangladesh	bangladesh	NOUN
bjp-22865	8	68	journals	journal	NOUN
bjp-22865	8	69	online	online	ADV
bjp-22865	8	70	,	,	PUNCT
bjp-22865	8	71	biological	biological	ADJ
bjp-22865	8	72	abstracts	abstract	NOUN
bjp-22865	8	73	,	,	PUNCT
bjp-22865	8	74	biosis	biosis	NOUN
bjp-22865	8	75	previews	preview	NOUN
bjp-22865	8	76	,	,	PUNCT
bjp-22865	8	77	cab	cab	NOUN
bjp-22865	8	78	abstracts	abstract	NOUN
bjp-22865	8	79	,	,	PUNCT
bjp-22865	8	80	current	current	ADJ
bjp-22865	8	81	abstracts	abstract	NOUN
bjp-22865	8	82	,	,	PUNCT
bjp-22865	8	83	directory	directory	NOUN
bjp-22865	8	84	of	of	ADP
bjp-22865	8	85	open	open	ADJ
bjp-22865	8	86	access	access	NOUN
bjp-22865	8	87	journals	journal	NOUN
bjp-22865	8	88	,	,	PUNCT
bjp-22865	8	89	embase	embase	NOUN
bjp-22865	8	90	/	/	SYM
bjp-22865	8	91	excerpta	excerpta	NOUN
bjp-22865	8	92	medica	medica	NOUN
bjp-22865	8	93	,	,	PUNCT
bjp-22865	8	94	google	google	PROPN
bjp-22865	8	95	scholar	scholar	NOUN
bjp-22865	8	96	,	,	PUNCT
bjp-22865	8	97	hinari	hinari	X
bjp-22865	8	98	(	(	PUNCT
bjp-22865	8	99	who	who	PRON
bjp-22865	8	100	)	)	PUNCT
bjp-22865	8	101	,	,	PUNCT
bjp-22865	8	102	international	international	ADJ
bjp-22865	8	103	pharmaceutical	pharmaceutical	ADJ
bjp-22865	8	104	abstracts	abstract	NOUN
bjp-22865	8	105	,	,	PUNCT
bjp-22865	8	106	open	open	ADJ
bjp-22865	8	107	j	j	PROPN
bjp-22865	8	108	-	-	PUNCT
bjp-22865	8	109	gate	gate	NOUN
bjp-22865	8	110	,	,	PUNCT
bjp-22865	8	111	science	science	NOUN
bjp-22865	8	112	citation	citation	NOUN
bjp-22865	8	113	index	index	NOUN
bjp-22865	8	114	expanded	expand	VERB
bjp-22865	8	115	,	,	PUNCT
bjp-22865	8	116	scopus	scopus	NOUN
bjp-22865	8	117	and	and	CCONJ
bjp-22865	8	118	social	social	ADJ
bjp-22865	8	119	sciences	sciences	PROPN
bjp-22865	8	120	citation	citation	NOUN
bjp-22865	8	121	index	index	NOUN
bjp-22865	8	122	issn	issn	PROPN
bjp-22865	8	123	:	:	PUNCT
bjp-22865	8	124	1991	1991	NUM
bjp-22865	8	125	-	-	SYM
bjp-22865	8	126	0088	0088	NUM
bjp-22865	8	127	;	;	PUNCT
bjp-22865	8	128	doi	doi	NOUN
bjp-22865	8	129	:	:	PUNCT
bjp-22865	8	130	10.3329	10.3329	NUM
bjp-22865	8	131	/	/	SYM
bjp-22865	8	132	bjp.v10i3.22865	bjp.v10i3.22865	PROPN
bjp-22865	8	133	abstract	abstract	NOUN
bjp-22865	8	134	the	the	DET
bjp-22865	8	135	study	study	NOUN
bjp-22865	8	136	aimed	aim	VERB
bjp-22865	8	137	to	to	PART
bjp-22865	8	138	determine	determine	VERB
bjp-22865	8	139	the	the	DET
bjp-22865	8	140	effect	effect	NOUN
bjp-22865	8	141	of	of	ADP
bjp-22865	8	142	tangeretin	tangeretin	NOUN
bjp-22865	8	143	in	in	ADP
bjp-22865	8	144	inhibiting	inhibit	VERB
bjp-22865	8	145	the	the	DET
bjp-22865	8	146	interleukin-1	interleukin-1	NOUN
bjp-22865	8	147	(	(	PUNCT
bjp-22865	8	148	il-1	il-1	ADV
bjp-22865	8	149	)	)	PUNCT
bjp-22865	8	150	-induced	-induce	VERB
bjp-22865	8	151	proliferation	proliferation	NOUN
bjp-22865	8	152	of	of	ADP
bjp-22865	8	153	rasfs	rasfs	NOUN
bjp-22865	8	154	and	and	CCONJ
bjp-22865	8	155	suppression	suppression	NOUN
bjp-22865	8	156	of	of	ADP
bjp-22865	8	157	the	the	DET
bjp-22865	8	158	production	production	NOUN
bjp-22865	8	159	of	of	ADP
bjp-22865	8	160	inflammatory	inflammatory	ADJ
bjp-22865	8	161	mediators	mediator	NOUN
bjp-22865	8	162	.	.	PUNCT
bjp-22865	9	1	rasfs	rasfs	PROPN
bjp-22865	9	2	were	be	AUX
bjp-22865	9	3	isolated	isolate	VERB
bjp-22865	9	4	from	from	ADP
bjp-22865	9	5	synovial	synovial	ADJ
bjp-22865	9	6	tissue	tissue	NOUN
bjp-22865	9	7	obtained	obtain	VERB
bjp-22865	9	8	from	from	ADP
bjp-22865	9	9	patients	patient	NOUN
bjp-22865	9	10	with	with	ADP
bjp-22865	9	11	ra	ra	PROPN
bjp-22865	9	12	during	during	ADP
bjp-22865	9	13	knee	knee	NOUN
bjp-22865	9	14	arthroscopy	arthroscopy	NOUN
bjp-22865	9	15	.	.	PUNCT
bjp-22865	10	1	the	the	DET
bjp-22865	10	2	cells	cell	NOUN
bjp-22865	10	3	were	be	AUX
bjp-22865	10	4	exposed	expose	VERB
bjp-22865	10	5	to	to	ADP
bjp-22865	10	6	il‑1	il‑1	NOUN
bjp-22865	10	7	(	(	PUNCT
bjp-22865	10	8	1.0	1.0	NUM
bjp-22865	10	9	ng	ng	PROPN
bjp-22865	10	10	/	/	SYM
bjp-22865	10	11	ml	ml	NOUN
bjp-22865	10	12	)	)	PUNCT
bjp-22865	10	13	and/	and/	NOUN
bjp-22865	10	14	or	or	CCONJ
bjp-22865	10	15	tangeretin	tangeretin	ADJ
bjp-22865	10	16	(	(	PUNCT
bjp-22865	10	17	50	50	NUM
bjp-22865	10	18	or	or	CCONJ
bjp-22865	10	19	100	100	NUM
bjp-22865	10	20	µm	µm	NUM
bjp-22865	10	21	)	)	PUNCT
bjp-22865	10	22	.	.	PUNCT
bjp-22865	11	1	cell	cell	NOUN
bjp-22865	11	2	viability	viability	NOUN
bjp-22865	11	3	was	be	AUX
bjp-22865	11	4	assessed	assess	VERB
bjp-22865	11	5	following	follow	VERB
bjp-22865	11	6	treatments	treatment	NOUN
bjp-22865	11	7	.	.	PUNCT
bjp-22865	12	1	expressions	expression	NOUN
bjp-22865	12	2	of	of	ADP
bjp-22865	12	3	mmps	mmp	NOUN
bjp-22865	12	4	and	and	CCONJ
bjp-22865	12	5	cox-2	cox-2	NUM
bjp-22865	12	6	were	be	AUX
bjp-22865	12	7	analysed	analyse	VERB
bjp-22865	12	8	by	by	ADP
bjp-22865	12	9	real	real	ADJ
bjp-22865	12	10	-	-	PUNCT
bjp-22865	12	11	time	time	NOUN
bjp-22865	12	12	pcr	pcr	ADJ
bjp-22865	12	13	and	and	CCONJ
bjp-22865	12	14	western	western	ADJ
bjp-22865	12	15	blotting	blotting	NOUN
bjp-22865	12	16	.	.	PUNCT
bjp-22865	13	1	production	production	NOUN
bjp-22865	13	2	of	of	ADP
bjp-22865	13	3	prostaglandin	prostaglandin	PROPN
bjp-22865	13	4	e2	e2	PROPN
bjp-22865	13	5	(	(	PUNCT
bjp-22865	13	6	pge2	pge2	PROPN
bjp-22865	13	7	)	)	PUNCT
bjp-22865	13	8	by	by	ADP
bjp-22865	13	9	rasfs	rasfs	PROPN
bjp-22865	13	10	were	be	AUX
bjp-22865	13	11	analysed	analyse	VERB
bjp-22865	13	12	by	by	ADP
bjp-22865	13	13	elisa	elisa	PROPN
bjp-22865	13	14	.	.	PUNCT
bjp-22865	14	1	expressions	expression	NOUN
bjp-22865	14	2	of	of	ADP
bjp-22865	14	3	mitogen	mitogen	NOUN
bjp-22865	14	4	activated	activate	VERB
bjp-22865	14	5	protein	protein	NOUN
bjp-22865	14	6	kinases	kinase	NOUN
bjp-22865	14	7	(	(	PUNCT
bjp-22865	14	8	mapks	mapks	NOUN
bjp-22865	14	9	)	)	PUNCT
bjp-22865	14	10	and	and	CCONJ
bjp-22865	14	11	nuclear	nuclear	ADJ
bjp-22865	14	12	factor	factor	NOUN
bjp-22865	14	13	-	-	PUNCT
bjp-22865	14	14	kb	kb	PROPN
bjp-22865	14	15	(	(	PUNCT
bjp-22865	14	16	nf	nf	PROPN
bjp-22865	14	17	-	-	PUNCT
bjp-22865	14	18	kb	kb	NOUN
bjp-22865	14	19	)	)	PUNCT
bjp-22865	14	20	were	be	AUX
bjp-22865	14	21	assessed	assess	VERB
bjp-22865	14	22	by	by	ADP
bjp-22865	14	23	western	western	ADJ
bjp-22865	14	24	blotting	blotting	NOUN
bjp-22865	14	25	.	.	PUNCT
bjp-22865	15	1	tangeretin	tangeretin	PROPN
bjp-22865	15	2	significantly	significantly	ADV
bjp-22865	15	3	inhibited	inhibit	VERB
bjp-22865	15	4	the	the	DET
bjp-22865	15	5	proliferation	proliferation	NOUN
bjp-22865	15	6	of	of	ADP
bjp-22865	15	7	rasfs	rasfs	PROPN
bjp-22865	15	8	,	,	PUNCT
bjp-22865	15	9	as	as	ADV
bjp-22865	15	10	well	well	ADV
bjp-22865	15	11	as	as	ADP
bjp-22865	15	12	down	down	ADV
bjp-22865	15	13	-	-	PUNCT
bjp-22865	15	14	regulated	regulate	VERB
bjp-22865	15	15	the	the	DET
bjp-22865	15	16	expression	expression	NOUN
bjp-22865	15	17	of	of	ADP
bjp-22865	15	18	mmp-1	mmp-1	NOUN
bjp-22865	15	19	,	,	PUNCT
bjp-22865	15	20	mmp-3	mmp-3	NUM
bjp-22865	15	21	and	and	CCONJ
bjp-22865	15	22	cox-2	cox-2	NUM
bjp-22865	15	23	mrna	mrna	NOUN
bjp-22865	15	24	and	and	CCONJ
bjp-22865	15	25	protein	protein	NOUN
bjp-22865	15	26	and	and	CCONJ
bjp-22865	15	27	also	also	ADV
bjp-22865	15	28	the	the	DET
bjp-22865	15	29	phosphorylation	phosphorylation	NOUN
bjp-22865	15	30	of	of	ADP
bjp-22865	15	31	erk	erk	PROPN
bjp-22865	15	32	,	,	PUNCT
bjp-22865	15	33	p38	p38	NOUN
bjp-22865	15	34	and	and	CCONJ
bjp-22865	15	35	jnk	jnk	PROPN
bjp-22865	15	36	.	.	PROPN
bjp-22865	16	1	raised	raise	VERB
bjp-22865	16	2	level	level	NOUN
bjp-22865	16	3	of	of	ADP
bjp-22865	16	4	expression	expression	NOUN
bjp-22865	16	5	of	of	ADP
bjp-22865	16	6	nf	nf	NOUN
bjp-22865	16	7	-	-	PUNCT
bjp-22865	16	8	κb	κb	NOUN
bjp-22865	16	9	and	and	CCONJ
bjp-22865	16	10	pge2	pge2	NOUN
bjp-22865	16	11	induced	induce	VERB
bjp-22865	16	12	by	by	ADP
bjp-22865	16	13	il-1	il-1	NOUN
bjp-22865	16	14	was	be	AUX
bjp-22865	16	15	reduced	reduce	VERB
bjp-22865	16	16	by	by	ADP
bjp-22865	16	17	tangeretin	tangeretin	PROPN
bjp-22865	16	18	.	.	PUNCT
bjp-22865	16	19	results	result	NOUN
bjp-22865	16	20	indicate	indicate	VERB
bjp-22865	16	21	that	that	DET
bjp-22865	16	22	tangeretin	tangeretin	NOUN
bjp-22865	16	23	was	be	AUX
bjp-22865	16	24	effective	effective	ADJ
bjp-22865	16	25	in	in	ADP
bjp-22865	16	26	inhibiting	inhibit	VERB
bjp-22865	16	27	the	the	DET
bjp-22865	16	28	synovial	synovial	ADJ
bjp-22865	16	29	fibroblast	fibroblast	ADJ
bjp-22865	16	30	proliferation	proliferation	NOUN
bjp-22865	16	31	,	,	PUNCT
bjp-22865	16	32	as	as	ADV
bjp-22865	16	33	well	well	ADV
bjp-22865	16	34	regulated	regulate	VERB
bjp-22865	16	35	mmps	mmp	NOUN
bjp-22865	16	36	,	,	PUNCT
bjp-22865	16	37	cox2	cox2	NOUN
bjp-22865	16	38	,	,	PUNCT
bjp-22865	16	39	pge2	pge2	NOUN
bjp-22865	16	40	via	via	ADP
bjp-22865	16	41	modulation	modulation	NOUN
bjp-22865	16	42	of	of	ADP
bjp-22865	16	43	p38	p38	NOUN
bjp-22865	16	44	mapk	mapk	NOUN
bjp-22865	16	45	,	,	PUNCT
bjp-22865	16	46	erk	erk	PROPN
bjp-22865	16	47	and	and	CCONJ
bjp-22865	16	48	jnk	jnk	PROPN
bjp-22865	16	49	pathways	pathway	NOUN
bjp-22865	16	50	.	.	PUNCT
bjp-22865	17	1	article	article	NOUN
bjp-22865	17	2	info	info	NOUN
bjp-22865	17	3	received	receive	VERB
bjp-22865	17	4	:	:	PUNCT
bjp-22865	17	5	4	4	NUM
bjp-22865	17	6	april	april	PROPN
bjp-22865	17	7	2015	2015	NUM
bjp-22865	17	8	accepted	accept	VERB
bjp-22865	17	9	:	:	PUNCT
bjp-22865	17	10	2	2	NUM
bjp-22865	17	11	may	may	PROPN
bjp-22865	17	12	2015	2015	NUM
bjp-22865	17	13	available	available	ADJ
bjp-22865	17	14	online	online	ADV
bjp-22865	17	15	:	:	PUNCT
bjp-22865	17	16	21	21	NUM
bjp-22865	17	17	august	august	PROPN
bjp-22865	17	18	2015	2015	NUM
bjp-22865	17	19	keywords	keyword	NOUN
bjp-22865	17	20	:	:	PUNCT
bjp-22865	17	21	interleukin-1	interleukin-1	NUM
bjp-22865	17	22	protein	protein	NOUN
bjp-22865	17	23	kinase	kinase	NOUN
bjp-22865	17	24	rheumatoid	rheumatoid	VERB
bjp-22865	17	25	arthritis	arthritis	NOUN
bjp-22865	17	26	tangeretin	tangeretin	NOUN
bjp-22865	17	27	number	number	NOUN
bjp-22865	17	28	of	of	ADP
bjp-22865	17	29	figures	figure	NOUN
bjp-22865	17	30	:	:	PUNCT
bjp-22865	17	31	5	5	NUM
bjp-22865	17	32	number	number	NOUN
bjp-22865	17	33	of	of	ADP
bjp-22865	17	34	tables	table	NOUN
bjp-22865	17	35	:	:	PUNCT
bjp-22865	17	36	0	0	NUM
bjp-22865	17	37	number	number	NOUN
bjp-22865	17	38	of	of	ADP
bjp-22865	17	39	refs	ref	NOUN
bjp-22865	17	40	:	:	PUNCT
bjp-22865	17	41	48	48	NUM
bjp-22865	17	42	correspondence	correspondence	NOUN
bjp-22865	17	43	:	:	PUNCT
bjp-22865	17	44	gl	gl	PROPN
bjp-22865	17	45	yz	yz	PROPN
bjp-22865	17	46	e	e	NOUN
bjp-22865	17	47	-	-	NOUN
bjp-22865	17	48	mail	mail	NOUN
bjp-22865	17	49	:	:	PUNCT
bjp-22865	17	50	ligangtpm@yeah.net	ligangtpm@yeah.net	NOUN
bjp-22865	17	51	zhouyan7703@gmail.com	zhouyan7703@gmail.com	NOUN
bjp-22865	17	52	tangeretin	tangeretin	PROPN
bjp-22865	17	53	inhibits	inhibit	VERB
bjp-22865	17	54	il-1β	il-1β	PROPN
bjp-22865	17	55	induced	induced	ADJ
bjp-22865	17	56	proliferation	proliferation	NOUN
bjp-22865	17	57	of	of	ADP
bjp-22865	17	58	rheumatoid	rheumatoid	NOUN
bjp-22865	17	59	synovial	synovial	ADJ
bjp-22865	17	60	fibroblasts	fibroblast	NOUN
bjp-22865	17	61	and	and	CCONJ
bjp-22865	17	62	the	the	DET
bjp-22865	17	63	production	production	NOUN
bjp-22865	17	64	of	of	ADP
bjp-22865	17	65	cox-2	cox-2	NOUN
bjp-22865	17	66	,	,	PUNCT
bjp-22865	17	67	pge2	pge2	NOUN
bjp-22865	17	68	and	and	CCONJ
bjp-22865	17	69	mmps	mmp	NOUN
bjp-22865	17	70	via	via	ADP
bjp-22865	17	71	modulation	modulation	NOUN
bjp-22865	17	72	of	of	ADP
bjp-22865	17	73	p38	p38	NOUN
bjp-22865	17	74	mapk	mapk	PROPN
bjp-22865	17	75	/	/	SYM
bjp-22865	17	76	erk	erk	PROPN
bjp-22865	17	77	/	/	SYM
bjp-22865	17	78	jnk	jnk	PROPN
bjp-22865	17	79	pathways	pathways	PROPN
bjp-22865	17	80	yong	yong	PROPN
bjp-22865	17	81	-	-	PUNCT
bjp-22865	17	82	ji	ji	PROPN
bjp-22865	17	83	li1	li1	NOUN
bjp-22865	17	84	,	,	PUNCT
bjp-22865	17	85	ting	ting	PROPN
bjp-22865	17	86	zhang1	zhang1	PROPN
bjp-22865	17	87	,	,	PUNCT
bjp-22865	17	88	jian	jian	PROPN
bjp-22865	17	89	-	-	PUNCT
bjp-22865	17	90	xin	xin	PROPN
bjp-22865	17	91	tu1	tu1	PROPN
bjp-22865	17	92	,	,	PUNCT
bjp-22865	17	93	gang	gang	PROPN
bjp-22865	17	94	li2	li2	PROPN
bjp-22865	17	95	and	and	CCONJ
bjp-22865	17	96	yan	yan	PROPN
bjp-22865	17	97	zhou1	zhou1	PROPN
bjp-22865	18	1	1department	1department	NUM
bjp-22865	18	2	of	of	ADP
bjp-22865	18	3	rheumatoid	rheumatoid	VERB
bjp-22865	18	4	immunology	immunology	NOUN
bjp-22865	18	5	and	and	CCONJ
bjp-22865	18	6	2chemoradiation	2chemoradiation	NUM
bjp-22865	18	7	oncology	oncology	NOUN
bjp-22865	18	8	,	,	PUNCT
bjp-22865	18	9	the	the	DET
bjp-22865	18	10	first	first	ADJ
bjp-22865	18	11	affiliated	affiliated	ADJ
bjp-22865	18	12	hospital	hospital	NOUN
bjp-22865	18	13	of	of	ADP
bjp-22865	18	14	wenzhou	wenzhou	PROPN
bjp-22865	18	15	medical	medical	PROPN
bjp-22865	18	16	university	university	PROPN
bjp-22865	18	17	,	,	PUNCT
bjp-22865	18	18	wenzhou	wenzhou	PROPN
bjp-22865	18	19	,	,	PUNCT
bjp-22865	18	20	zhejiang	zhejiang	PROPN
bjp-22865	18	21	325	325	NUM
bjp-22865	18	22	000	000	NUM
bjp-22865	18	23	,	,	PUNCT
bjp-22865	18	24	china	china	PROPN
bjp-22865	18	25	.	.	PUNCT
bjp-22865	19	1	http://www.bioxbio.com/if/html/bangl-j-pharmacol.html	http://www.bioxbio.com/if/html/bangl-j-pharmacol.html	PROPN
bjp-22865	19	2	phosphorylation	phosphorylation	NOUN
bjp-22865	19	3	of	of	ADP
bjp-22865	19	4	transcription	transcription	NOUN
bjp-22865	19	5	factor	factor	NOUN
bjp-22865	19	6	nf	nf	NOUN
bjp-22865	19	7	-	-	PUNCT
bjp-22865	19	8	κb	κb	PROPN
bjp-22865	19	9	(	(	PUNCT
bjp-22865	19	10	su	su	PROPN
bjp-22865	19	11	and	and	CCONJ
bjp-22865	19	12	karin	karin	PROPN
bjp-22865	19	13	,	,	PUNCT
bjp-22865	19	14	1996	1996	NUM
bjp-22865	19	15	;	;	PUNCT
bjp-22865	19	16	dong	dong	PROPN
bjp-22865	19	17	et	et	PROPN
bjp-22865	19	18	al	al	PROPN
bjp-22865	19	19	.	.	PROPN
bjp-22865	19	20	,	,	PUNCT
bjp-22865	19	21	2002	2002	NUM
bjp-22865	19	22	)	)	PUNCT
bjp-22865	19	23	.	.	PUNCT
bjp-22865	20	1	further	further	ADJ
bjp-22865	20	2	research	research	NOUN
bjp-22865	20	3	have	have	AUX
bjp-22865	20	4	demonstrated	demonstrate	VERB
bjp-22865	20	5	the	the	DET
bjp-22865	20	6	activation	activation	NOUN
bjp-22865	20	7	of	of	ADP
bjp-22865	20	8	the	the	DET
bjp-22865	20	9	members	member	NOUN
bjp-22865	20	10	of	of	ADP
bjp-22865	20	11	signalling	signal	VERB
bjp-22865	20	12	cascades	cascade	NOUN
bjp-22865	20	13	such	such	ADJ
bjp-22865	20	14	as	as	ADP
bjp-22865	20	15	nf	nf	NOUN
bjp-22865	20	16	-	-	PUNCT
bjp-22865	20	17	κb	κb	ADJ
bjp-22865	20	18	p65	p65	NOUN
bjp-22865	20	19	,	,	PUNCT
bjp-22865	20	20	and	and	CCONJ
bjp-22865	20	21	extra	extra	ADJ
bjp-22865	20	22	cellular	cellular	ADJ
bjp-22865	20	23	signal	signal	NOUN
bjp-22865	20	24	-	-	PUNCT
bjp-22865	20	25	regulated	regulate	VERB
bjp-22865	20	26	kinase	kinase	NOUN
bjp-22865	20	27	(	(	PUNCT
bjp-22865	20	28	erk	erk	PROPN
bjp-22865	20	29	)	)	PUNCT
bjp-22865	20	30	,	,	PUNCT
bjp-22865	20	31	junn	junn	PROPN
bjp-22865	20	32	-	-	PUNCT
bjp-22865	20	33	terminal	terminal	ADJ
bjp-22865	20	34	kinase	kinase	PROPN
bjp-22865	20	35	(	(	PUNCT
bjp-22865	20	36	jnk	jnk	PROPN
bjp-22865	20	37	)	)	PUNCT
bjp-22865	20	38	and	and	CCONJ
bjp-22865	20	39	p38mapks	p38mapks	VERB
bjp-22865	20	40	in	in	ADP
bjp-22865	20	41	ra	ra	PROPN
bjp-22865	20	42	synovial	synovial	ADJ
bjp-22865	20	43	tissue	tissue	NOUN
bjp-22865	20	44	.	.	PUNCT
bjp-22865	21	1	upon	upon	SCONJ
bjp-22865	21	2	activation	activation	NOUN
bjp-22865	21	3	erk	erk	PROPN
bjp-22865	21	4	,	,	PUNCT
bjp-22865	21	5	jnk	jnk	PROPN
bjp-22865	21	6	and	and	CCONJ
bjp-22865	21	7	p38mapk	p38mapk	NOUN
bjp-22865	21	8	play	play	VERB
bjp-22865	21	9	vital	vital	ADJ
bjp-22865	21	10	roles	role	NOUN
bjp-22865	21	11	in	in	ADP
bjp-22865	21	12	synovial	synovial	ADJ
bjp-22865	21	13	inflammation	inflammation	NOUN
bjp-22865	21	14	and	and	CCONJ
bjp-22865	21	15	proliferation	proliferation	NOUN
bjp-22865	21	16	of	of	ADP
bjp-22865	21	17	synovial	synovial	ADJ
bjp-22865	21	18	cells	cell	NOUN
bjp-22865	21	19	(	(	PUNCT
bjp-22865	21	20	luo	luo	PROPN
bjp-22865	21	21	et	et	PROPN
bjp-22865	21	22	al	al	PROPN
bjp-22865	21	23	.	.	PROPN
bjp-22865	21	24	,	,	PUNCT
bjp-22865	21	25	2010	2010	NUM
bjp-22865	21	26	;	;	PUNCT
bjp-22865	21	27	yang	yang	PROPN
bjp-22865	21	28	et	et	PROPN
bjp-22865	21	29	al	al	PROPN
bjp-22865	21	30	.	.	PROPN
bjp-22865	21	31	,	,	PUNCT
bjp-22865	21	32	2010	2010	NUM
bjp-22865	21	33	)	)	PUNCT
bjp-22865	21	34	.	.	PUNCT
bjp-22865	22	1	present	present	ADJ
bjp-22865	22	2	day	day	NOUN
bjp-22865	22	3	treatment	treatment	NOUN
bjp-22865	22	4	strategies	strategy	NOUN
bjp-22865	22	5	towards	towards	ADP
bjp-22865	22	6	ra	ra	PROPN
bjp-22865	22	7	are	be	AUX
bjp-22865	22	8	targeted	target	VERB
bjp-22865	22	9	predominantly	predominantly	ADV
bjp-22865	22	10	against	against	ADP
bjp-22865	22	11	inflammatory	inflammatory	ADJ
bjp-22865	22	12	mediators	mediator	NOUN
bjp-22865	22	13	.	.	PUNCT
bjp-22865	23	1	owing	owe	VERB
bjp-22865	23	2	to	to	ADP
bjp-22865	23	3	the	the	DET
bjp-22865	23	4	adverse	adverse	ADJ
bjp-22865	23	5	effects	effect	NOUN
bjp-22865	23	6	of	of	ADP
bjp-22865	23	7	the	the	DET
bjp-22865	23	8	chronic	chronic	ADJ
bjp-22865	23	9	usage	usage	NOUN
bjp-22865	23	10	of	of	ADP
bjp-22865	23	11	anti	anti	ADJ
bjp-22865	23	12	-	-	ADJ
bjp-22865	23	13	inflammatory	inflammatory	ADJ
bjp-22865	23	14	drugs	drug	NOUN
bjp-22865	23	15	in	in	ADP
bjp-22865	23	16	the	the	DET
bjp-22865	23	17	treatment	treatment	NOUN
bjp-22865	23	18	,	,	PUNCT
bjp-22865	23	19	exploring	explore	VERB
bjp-22865	23	20	alternative	alternative	ADJ
bjp-22865	23	21	means	mean	NOUN
bjp-22865	23	22	is	be	AUX
bjp-22865	23	23	indispensible	indispensible	ADJ
bjp-22865	23	24	.	.	PUNCT
bjp-22865	24	1	flavonoids	flavonoid	NOUN
bjp-22865	24	2	are	be	AUX
bjp-22865	24	3	widely	widely	ADV
bjp-22865	24	4	present	present	ADJ
bjp-22865	24	5	in	in	ADP
bjp-22865	24	6	fruit	fruit	NOUN
bjp-22865	24	7	and	and	CCONJ
bjp-22865	24	8	vegetables	vegetable	NOUN
bjp-22865	24	9	.	.	PUNCT
bjp-22865	25	1	citrus	citrus	NOUN
bjp-22865	25	2	flavonoids	flavonoid	NOUN
bjp-22865	25	3	have	have	VERB
bjp-22865	25	4	a	a	DET
bjp-22865	25	5	wide	wide	ADJ
bjp-22865	25	6	range	range	NOUN
bjp-22865	25	7	of	of	ADP
bjp-22865	25	8	biological	biological	ADJ
bjp-22865	25	9	activities	activity	NOUN
bjp-22865	25	10	including	include	VERB
bjp-22865	25	11	anticarcinogenic	anticarcinogenic	NOUN
bjp-22865	25	12	and	and	CCONJ
bjp-22865	25	13	antitumor	antitumor	PROPN
bjp-22865	25	14	.	.	PUNCT
bjp-22865	26	1	tangeretin	tangeretin	PROPN
bjp-22865	26	2	(	(	PUNCT
bjp-22865	26	3	5,6,7,8,4′	5,6,7,8,4′	NUM
bjp-22865	26	4	-pentamethoxy	-pentamethoxy	ADJ
bjp-22865	26	5	flavone	flavone	NOUN
bjp-22865	26	6	)	)	PUNCT
bjp-22865	26	7	is	be	AUX
bjp-22865	26	8	present	present	ADJ
bjp-22865	26	9	in	in	ADP
bjp-22865	26	10	oranges	orange	NOUN
bjp-22865	26	11	and	and	CCONJ
bjp-22865	26	12	in	in	ADP
bjp-22865	26	13	other	other	ADJ
bjp-22865	26	14	citrus	citrus	NOUN
bjp-22865	26	15	peels	peel	NOUN
bjp-22865	26	16	(	(	PUNCT
bjp-22865	26	17	dong	dong	NOUN
bjp-22865	26	18	et	et	PROPN
bjp-22865	26	19	al	al	PROPN
bjp-22865	26	20	.	.	PROPN
bjp-22865	26	21	,	,	PUNCT
bjp-22865	26	22	2014	2014	NUM
bjp-22865	26	23	)	)	PUNCT
bjp-22865	26	24	.	.	PUNCT
bjp-22865	27	1	it	it	PRON
bjp-22865	27	2	has	have	AUX
bjp-22865	27	3	been	be	AUX
bjp-22865	27	4	reported	report	VERB
bjp-22865	27	5	to	to	PART
bjp-22865	27	6	exhibit	exhibit	VERB
bjp-22865	27	7	various	various	ADJ
bjp-22865	27	8	pharmacological	pharmacological	ADJ
bjp-22865	27	9	activities	activity	NOUN
bjp-22865	27	10	:	:	PUNCT
bjp-22865	27	11	anti	anti	ADJ
bjp-22865	27	12	-	-	ADJ
bjp-22865	27	13	oxidant	oxidant	ADJ
bjp-22865	27	14	(	(	PUNCT
bjp-22865	27	15	chen	chen	PROPN
bjp-22865	27	16	et	et	PROPN
bjp-22865	27	17	al	al	PROPN
bjp-22865	27	18	.	.	PROPN
bjp-22865	27	19	,	,	PUNCT
bjp-22865	27	20	2012	2012	NUM
bjp-22865	27	21	)	)	PUNCT
bjp-22865	27	22	,	,	PUNCT
bjp-22865	27	23	neuroprotective	neuroprotective	ADJ
bjp-22865	27	24	(	(	PUNCT
bjp-22865	27	25	datla	datla	NOUN
bjp-22865	27	26	et	et	PROPN
bjp-22865	27	27	al	al	PROPN
bjp-22865	27	28	.	.	PROPN
bjp-22865	27	29	,	,	PUNCT
bjp-22865	27	30	2001	2001	NUM
bjp-22865	27	31	)	)	PUNCT
bjp-22865	27	32	,	,	PUNCT
bjp-22865	27	33	anti	anti	ADJ
bjp-22865	27	34	-	-	ADJ
bjp-22865	27	35	inflammatory	inflammatory	ADJ
bjp-22865	27	36	activity	activity	NOUN
bjp-22865	27	37	(	(	PUNCT
bjp-22865	27	38	ho	ho	PROPN
bjp-22865	27	39	and	and	CCONJ
bjp-22865	27	40	kuo	kuo	PROPN
bjp-22865	27	41	,	,	PUNCT
bjp-22865	27	42	2014	2014	NUM
bjp-22865	27	43	;	;	PUNCT
bjp-22865	27	44	shu	shu	PROPN
bjp-22865	27	45	et	et	PROPN
bjp-22865	27	46	al	al	PROPN
bjp-22865	27	47	.	.	PROPN
bjp-22865	27	48	,	,	PUNCT
bjp-22865	27	49	2014	2014	NUM
bjp-22865	27	50	)	)	PUNCT
bjp-22865	27	51	and	and	CCONJ
bjp-22865	27	52	inhibition	inhibition	NOUN
bjp-22865	27	53	of	of	ADP
bjp-22865	27	54	cancer	cancer	NOUN
bjp-22865	27	55	cell	cell	NOUN
bjp-22865	27	56	proliferation	proliferation	NOUN
bjp-22865	27	57	(	(	PUNCT
bjp-22865	27	58	dong	dong	NOUN
bjp-22865	27	59	et	et	PROPN
bjp-22865	27	60	al	al	PROPN
bjp-22865	27	61	.	.	PROPN
bjp-22865	27	62	,	,	PUNCT
bjp-22865	27	63	2014	2014	NUM
bjp-22865	27	64	;	;	PUNCT
bjp-22865	27	65	periyaswamy	periyaswamy	NOUN
bjp-22865	27	66	et	et	PROPN
bjp-22865	27	67	al	al	PROPN
bjp-22865	27	68	.	.	PROPN
bjp-22865	27	69	,	,	PUNCT
bjp-22865	27	70	2015	2015	NUM
bjp-22865	27	71	)	)	PUNCT
bjp-22865	27	72	.	.	PUNCT
bjp-22865	28	1	tangeretin	tangeretin	PROPN
bjp-22865	28	2	has	have	AUX
bjp-22865	28	3	been	be	AUX
bjp-22865	28	4	reported	report	VERB
bjp-22865	28	5	to	to	PART
bjp-22865	28	6	reduce	reduce	VERB
bjp-22865	28	7	the	the	DET
bjp-22865	28	8	production	production	NOUN
bjp-22865	28	9	of	of	ADP
bjp-22865	28	10	nitric	nitric	ADJ
bjp-22865	28	11	oxide	oxide	NOUN
bjp-22865	28	12	(	(	PUNCT
bjp-22865	28	13	no	no	NOUN
bjp-22865	28	14	)	)	PUNCT
bjp-22865	28	15	by	by	ADP
bjp-22865	28	16	inhibition	inhibition	NOUN
bjp-22865	28	17	of	of	ADP
bjp-22865	28	18	lpsinduced	lpsinduced	ADJ
bjp-22865	28	19	expression	expression	NOUN
bjp-22865	28	20	of	of	ADP
bjp-22865	28	21	nitric	nitric	ADJ
bjp-22865	28	22	oxide	oxide	NOUN
bjp-22865	28	23	synthase	synthase	NOUN
bjp-22865	28	24	(	(	PUNCT
bjp-22865	28	25	inos	ino	NOUN
bjp-22865	28	26	)	)	PUNCT
bjp-22865	28	27	and	and	CCONJ
bjp-22865	28	28	cox-2	cox-2	ADV
bjp-22865	28	29	in	in	ADP
bjp-22865	28	30	microglial	microglial	ADJ
bjp-22865	28	31	cells	cell	NOUN
bjp-22865	28	32	(	(	PUNCT
bjp-22865	28	33	shu	shu	NOUN
bjp-22865	28	34	et	et	PROPN
bjp-22865	28	35	al	al	PROPN
bjp-22865	28	36	.	.	PROPN
bjp-22865	28	37	,	,	PUNCT
bjp-22865	28	38	2014	2014	NUM
bjp-22865	28	39	)	)	PUNCT
bjp-22865	28	40	.	.	PUNCT
bjp-22865	29	1	considering	consider	VERB
bjp-22865	29	2	the	the	DET
bjp-22865	29	3	biological	biological	ADJ
bjp-22865	29	4	activities	activity	NOUN
bjp-22865	29	5	of	of	ADP
bjp-22865	29	6	tangeretin	tangeretin	PROPN
bjp-22865	29	7	,	,	PUNCT
bjp-22865	29	8	we	we	PRON
bjp-22865	29	9	investigated	investigate	VERB
bjp-22865	29	10	its	its	PRON
bjp-22865	29	11	effects	effect	NOUN
bjp-22865	29	12	in	in	ADP
bjp-22865	29	13	proliferation	proliferation	NOUN
bjp-22865	29	14	of	of	ADP
bjp-22865	29	15	rheumatoid	rheumatoid	NOUN
bjp-22865	29	16	synovial	synovial	ADJ
bjp-22865	29	17	fibroblasts	fibroblast	NOUN
bjp-22865	29	18	and	and	CCONJ
bjp-22865	29	19	production	production	NOUN
bjp-22865	29	20	of	of	ADP
bjp-22865	29	21	chemokines	chemokine	NOUN
bjp-22865	29	22	by	by	ADP
bjp-22865	29	23	rasfs	rasfs	PROPN
bjp-22865	29	24	.	.	PUNCT
bjp-22865	30	1	influence	influence	NOUN
bjp-22865	30	2	of	of	ADP
bjp-22865	30	3	tangeretin	tangeretin	NOUN
bjp-22865	30	4	on	on	ADP
bjp-22865	30	5	various	various	ADJ
bjp-22865	30	6	signal	signal	ADJ
bjp-22865	30	7	transduction	transduction	NOUN
bjp-22865	30	8	pathways	pathway	NOUN
bjp-22865	30	9	involved	involve	VERB
bjp-22865	30	10	in	in	ADP
bjp-22865	30	11	inflammation	inflammation	NOUN
bjp-22865	30	12	were	be	AUX
bjp-22865	30	13	also	also	ADV
bjp-22865	30	14	evaluated	evaluate	VERB
bjp-22865	30	15	.	.	PUNCT
bjp-22865	31	1	materials	material	NOUN
bjp-22865	31	2	and	and	CCONJ
bjp-22865	31	3	methods	method	NOUN
bjp-22865	31	4	reagents	reagent	NOUN
bjp-22865	31	5	and	and	CCONJ
bjp-22865	31	6	chemicals	chemical	NOUN
bjp-22865	31	7	:	:	PUNCT
bjp-22865	31	8	tangeretin	tangeretin	NUM
bjp-22865	31	9	was	be	AUX
bjp-22865	31	10	obtained	obtain	VERB
bjp-22865	31	11	from	from	ADP
bjp-22865	31	12	sigma‑aldrich	sigma‑aldrich	PROPN
bjp-22865	31	13	(	(	PUNCT
bjp-22865	31	14	st	st	PROPN
bjp-22865	31	15	.	.	PROPN
bjp-22865	31	16	louis	louis	PROPN
bjp-22865	31	17	,	,	PUNCT
bjp-22865	31	18	mo	mo	PROPN
bjp-22865	31	19	,	,	PUNCT
bjp-22865	31	20	usa	usa	PROPN
bjp-22865	31	21	)	)	PUNCT
bjp-22865	31	22	and	and	CCONJ
bjp-22865	31	23	dissolved	dissolve	VERB
bjp-22865	31	24	in	in	ADP
bjp-22865	31	25	dmso	dmso	NOUN
bjp-22865	31	26	with	with	ADP
bjp-22865	31	27	a	a	DET
bjp-22865	31	28	concentration	concentration	NOUN
bjp-22865	31	29	of	of	ADP
bjp-22865	31	30	100	100	NUM
bjp-22865	31	31	mm	mm	NOUN
bjp-22865	31	32	stock	stock	NOUN
bjp-22865	31	33	solution	solution	NOUN
bjp-22865	31	34	.	.	PUNCT
bjp-22865	32	1	fetal	fetal	ADJ
bjp-22865	32	2	bovine	bovine	NOUN
bjp-22865	32	3	serum	serum	NOUN
bjp-22865	32	4	(	(	PUNCT
bjp-22865	32	5	fbs	fbs	PROPN
bjp-22865	32	6	)	)	PUNCT
bjp-22865	32	7	was	be	AUX
bjp-22865	32	8	obtained	obtain	VERB
bjp-22865	32	9	from	from	ADP
bjp-22865	32	10	sigma‑aldrich	sigma‑aldrich	PROPN
bjp-22865	32	11	(	(	PUNCT
bjp-22865	32	12	st	st	PROPN
bjp-22865	32	13	.	.	PROPN
bjp-22865	32	14	louis	louis	PROPN
bjp-22865	32	15	,	,	PUNCT
bjp-22865	32	16	mo	mo	PROPN
bjp-22865	32	17	,	,	PUNCT
bjp-22865	32	18	usa	usa	PROPN
bjp-22865	32	19	)	)	PUNCT
bjp-22865	32	20	.	.	PUNCT
bjp-22865	33	1	recombinant	recombinant	ADJ
bjp-22865	33	2	human	human	ADJ
bjp-22865	33	3	il‑1	il‑1	NOUN
bjp-22865	33	4	was	be	AUX
bjp-22865	33	5	purchased	purchase	VERB
bjp-22865	33	6	from	from	ADP
bjp-22865	33	7	cell	cell	NOUN
bjp-22865	33	8	signaling	signal	VERB
bjp-22865	33	9	technology	technology	NOUN
bjp-22865	33	10	(	(	PUNCT
bjp-22865	33	11	beverly	beverly	PROPN
bjp-22865	33	12	,	,	PUNCT
bjp-22865	33	13	md	md	PROPN
bjp-22865	33	14	,	,	PUNCT
bjp-22865	33	15	usa	usa	PROPN
bjp-22865	33	16	)	)	PUNCT
bjp-22865	33	17	.	.	PUNCT
bjp-22865	34	1	antibodies	antibodie	VERB
bjp-22865	34	2	against	against	ADP
bjp-22865	34	3	ikb	ikb	PROPN
bjp-22865	34	4	,	,	PUNCT
bjp-22865	34	5	nf‑κb	nf‑κb	PROPN
bjp-22865	34	6	(	(	PUNCT
bjp-22865	34	7	p65	p65	NOUN
bjp-22865	34	8	)	)	PUNCT
bjp-22865	34	9	,	,	PUNCT
bjp-22865	34	10	erk	erk	PROPN
bjp-22865	34	11	,	,	PUNCT
bjp-22865	34	12	jnk	jnk	PROPN
bjp-22865	34	13	,	,	PUNCT
bjp-22865	34	14	p38	p38	NOUN
bjp-22865	34	15	,	,	PUNCT
bjp-22865	34	16	p‑erk	p‑erk	NOUN
bjp-22865	34	17	,	,	PUNCT
bjp-22865	34	18	p‑jnk	p‑jnk	NOUN
bjp-22865	34	19	,	,	PUNCT
bjp-22865	34	20	p‑p38	p‑p38	PROPN
bjp-22865	34	21	,	,	PUNCT
bjp-22865	34	22	‑actin	‑actin	X
bjp-22865	34	23	(	(	PUNCT
bjp-22865	34	24	cell	cell	NOUN
bjp-22865	34	25	signaling	signal	VERB
bjp-22865	34	26	technology	technology	NOUN
bjp-22865	34	27	(	(	PUNCT
bjp-22865	34	28	beverly	beverly	PROPN
bjp-22865	34	29	,	,	PUNCT
bjp-22865	34	30	md	md	PROPN
bjp-22865	34	31	,	,	PUNCT
bjp-22865	34	32	usa	usa	PROPN
bjp-22865	34	33	)	)	PUNCT
bjp-22865	34	34	,	,	PUNCT
bjp-22865	34	35	mmp‑1	mmp‑1	NOUN
bjp-22865	34	36	,	,	PUNCT
bjp-22865	34	37	mmp‑3	mmp‑3	NOUN
bjp-22865	34	38	and	and	CCONJ
bjp-22865	34	39	tissue	tissue	NOUN
bjp-22865	34	40	inhibitors	inhibitor	NOUN
bjp-22865	34	41	of	of	ADP
bjp-22865	34	42	metalloproteinases	metalloproteinase	NOUN
bjp-22865	34	43	(	(	PUNCT
bjp-22865	34	44	timp	timp	NOUN
bjp-22865	34	45	)	)	PUNCT
bjp-22865	34	46	,	,	PUNCT
bjp-22865	34	47	cox‑2	cox‑2	NOUN
bjp-22865	34	48	(	(	PUNCT
bjp-22865	34	49	santa	santa	PROPN
bjp-22865	34	50	cruz	cruz	PROPN
bjp-22865	34	51	biotechnology	biotechnology	PROPN
bjp-22865	34	52	,	,	PUNCT
bjp-22865	34	53	inc	inc	PROPN
bjp-22865	34	54	.	.	PROPN
bjp-22865	34	55	,	,	PUNCT
bjp-22865	34	56	santa	santa	PROPN
bjp-22865	34	57	cruz	cruz	PROPN
bjp-22865	34	58	,	,	PUNCT
bjp-22865	34	59	ca	ca	PROPN
bjp-22865	34	60	,	,	PUNCT
bjp-22865	34	61	usa	usa	PROPN
bjp-22865	34	62	)	)	PUNCT
bjp-22865	34	63	were	be	AUX
bjp-22865	34	64	used	use	VERB
bjp-22865	34	65	in	in	ADP
bjp-22865	34	66	western	western	ADJ
bjp-22865	34	67	blot	blot	NOUN
bjp-22865	34	68	analysis	analysis	NOUN
bjp-22865	34	69	.	.	PUNCT
bjp-22865	35	1	all	all	DET
bjp-22865	35	2	other	other	ADJ
bjp-22865	35	3	chemicals	chemical	NOUN
bjp-22865	35	4	used	use	VERB
bjp-22865	35	5	in	in	ADP
bjp-22865	35	6	the	the	DET
bjp-22865	35	7	investigation	investigation	NOUN
bjp-22865	35	8	were	be	AUX
bjp-22865	35	9	purchased	purchase	VERB
bjp-22865	35	10	from	from	ADP
bjp-22865	35	11	sigma	sigma	PROPN
bjp-22865	35	12	-	-	PUNCT
bjp-22865	35	13	aldrich	aldrich	PROPN
bjp-22865	35	14	,	,	PUNCT
bjp-22865	35	15	(	(	PUNCT
bjp-22865	35	16	st	st	PROPN
bjp-22865	35	17	.	.	PROPN
bjp-22865	35	18	louis	louis	PROPN
bjp-22865	35	19	,	,	PUNCT
bjp-22865	35	20	mo	mo	PROPN
bjp-22865	35	21	,	,	PUNCT
bjp-22865	35	22	usa	usa	PROPN
bjp-22865	35	23	)	)	PUNCT
bjp-22865	35	24	unless	unless	SCONJ
bjp-22865	35	25	otherwise	otherwise	ADV
bjp-22865	35	26	specified	specify	VERB
bjp-22865	35	27	.	.	PUNCT
bjp-22865	36	1	isolation	isolation	NOUN
bjp-22865	36	2	and	and	CCONJ
bjp-22865	36	3	culture	culture	NOUN
bjp-22865	36	4	of	of	ADP
bjp-22865	36	5	rasfs	rasfs	PROPN
bjp-22865	36	6	:	:	PUNCT
bjp-22865	36	7	this	this	DET
bjp-22865	36	8	study	study	NOUN
bjp-22865	36	9	was	be	AUX
bjp-22865	36	10	approved	approve	VERB
bjp-22865	36	11	by	by	ADP
bjp-22865	36	12	the	the	DET
bjp-22865	36	13	national	national	PROPN
bjp-22865	36	14	university	university	PROPN
bjp-22865	36	15	hospital	hospital	PROPN
bjp-22865	36	16	ethical	ethical	PROPN
bjp-22865	36	17	committee	committee	PROPN
bjp-22865	36	18	.	.	PUNCT
bjp-22865	37	1	synovial	synovial	ADJ
bjp-22865	37	2	tissues	tissue	NOUN
bjp-22865	37	3	were	be	AUX
bjp-22865	37	4	obtained	obtain	VERB
bjp-22865	37	5	from	from	ADP
bjp-22865	37	6	patients	patient	NOUN
bjp-22865	37	7	at	at	ADP
bjp-22865	37	8	the	the	DET
bjp-22865	37	9	total	total	ADJ
bjp-22865	37	10	knee	knee	NOUN
bjp-22865	37	11	arthroplasty	arthroplasty	NOUN
bjp-22865	37	12	in	in	ADP
bjp-22865	37	13	accordance	accordance	NOUN
bjp-22865	37	14	with	with	ADP
bjp-22865	37	15	the	the	DET
bjp-22865	37	16	american	american	PROPN
bjp-22865	37	17	college	college	PROPN
bjp-22865	37	18	of	of	ADP
bjp-22865	37	19	rheumatology	rheumatology	NOUN
bjp-22865	37	20	criteria	criterion	NOUN
bjp-22865	37	21	for	for	ADP
bjp-22865	37	22	ra	ra	PROPN
bjp-22865	37	23	(	(	PUNCT
bjp-22865	37	24	arnett	arnett	PROPN
bjp-22865	37	25	et	et	PROPN
bjp-22865	37	26	al	al	PROPN
bjp-22865	37	27	.	.	PROPN
bjp-22865	37	28	,	,	PUNCT
bjp-22865	37	29	1998	1998	NUM
bjp-22865	37	30	)	)	PUNCT
bjp-22865	37	31	and	and	CCONJ
bjp-22865	37	32	as	as	SCONJ
bjp-22865	37	33	previously	previously	ADV
bjp-22865	37	34	described	describe	VERB
bjp-22865	37	35	by	by	ADP
bjp-22865	37	36	lee	lee	PROPN
bjp-22865	37	37	et	et	PROPN
bjp-22865	37	38	al	al	PROPN
bjp-22865	37	39	.	.	PROPN
bjp-22865	38	1	(	(	PUNCT
bjp-22865	38	2	2006	2006	NUM
bjp-22865	38	3	)	)	PUNCT
bjp-22865	39	1	and	and	CCONJ
bjp-22865	39	2	informed	inform	VERB
bjp-22865	39	3	consent	consent	NOUN
bjp-22865	39	4	was	be	AUX
bjp-22865	39	5	obtained	obtain	VERB
bjp-22865	39	6	from	from	ADP
bjp-22865	39	7	all	all	DET
bjp-22865	39	8	patients	patient	NOUN
bjp-22865	39	9	.	.	PUNCT
bjp-22865	40	1	cells	cell	NOUN
bjp-22865	40	2	were	be	AUX
bjp-22865	40	3	incubated	incubate	VERB
bjp-22865	40	4	at	at	ADP
bjp-22865	40	5	37	37	NUM
bjp-22865	40	6	°	°	ADP
bjp-22865	40	7	c	c	NOUN
bjp-22865	40	8	in	in	ADP
bjp-22865	40	9	5	5	NUM
bjp-22865	40	10	%	%	NOUN
bjp-22865	40	11	co2	co2	NOUN
bjp-22865	40	12	in	in	ADP
bjp-22865	40	13	rpmi	rpmi	NOUN
bjp-22865	40	14	1640	1640	NUM
bjp-22865	40	15	medium	medium	NOUN
bjp-22865	40	16	supplemented	supplement	VERB
bjp-22865	40	17	with	with	ADP
bjp-22865	40	18	10	10	NUM
bjp-22865	40	19	%	%	NOUN
bjp-22865	40	20	(	(	PUNCT
bjp-22865	40	21	v	v	NOUN
bjp-22865	40	22	/	/	SYM
bjp-22865	40	23	v	v	NOUN
bjp-22865	40	24	)	)	PUNCT
bjp-22865	40	25	fbs	fbs	PROPN
bjp-22865	40	26	,	,	PUNCT
bjp-22865	40	27	100	100	NUM
bjp-22865	40	28	units/	units/	NUM
bjp-22865	40	29	ml	ml	NOUN
bjp-22865	40	30	of	of	ADP
bjp-22865	40	31	penicillin	penicillin	NOUN
bjp-22865	40	32	,	,	PUNCT
bjp-22865	40	33	and	and	CCONJ
bjp-22865	40	34	100	100	NUM
bjp-22865	40	35	μg	μg	NOUN
bjp-22865	40	36	/	/	SYM
bjp-22865	40	37	ml	ml	PROPN
bjp-22865	40	38	of	of	ADP
bjp-22865	40	39	streptomycin	streptomycin	PROPN
bjp-22865	40	40	.	.	PUNCT
bjp-22865	41	1	the	the	DET
bjp-22865	41	2	rasfs	rasfs	PROPN
bjp-22865	41	3	were	be	AUX
bjp-22865	41	4	isolated	isolate	VERB
bjp-22865	41	5	after	after	ADP
bjp-22865	41	6	3	3	NUM
bjp-22865	41	7	-	-	SYM
bjp-22865	41	8	7	7	NUM
bjp-22865	41	9	passages	passage	NOUN
bjp-22865	41	10	.	.	PUNCT
bjp-22865	42	1	the	the	DET
bjp-22865	42	2	synovial	synovial	ADJ
bjp-22865	42	3	cells	cell	NOUN
bjp-22865	42	4	were	be	AUX
bjp-22865	42	5	homogeneous	homogeneous	ADJ
bjp-22865	42	6	in	in	ADP
bjp-22865	42	7	morphology	morphology	NOUN
bjp-22865	42	8	and	and	CCONJ
bjp-22865	42	9	had	have	VERB
bjp-22865	42	10	the	the	DET
bjp-22865	42	11	manifestation	manifestation	NOUN
bjp-22865	42	12	of	of	ADP
bjp-22865	42	13	rasfs	rasfs	NOUN
bjp-22865	42	14	with	with	ADP
bjp-22865	42	15	distinctive	distinctive	ADJ
bjp-22865	42	16	fibroblastoid	fibroblastoid	NOUN
bjp-22865	42	17	configuration	configuration	NOUN
bjp-22865	42	18	.	.	PUNCT
bjp-22865	43	1	purity	purity	NOUN
bjp-22865	43	2	of	of	ADP
bjp-22865	43	3	the	the	DET
bjp-22865	43	4	cells	cell	NOUN
bjp-22865	43	5	were	be	AUX
bjp-22865	43	6	tested	test	VERB
bjp-22865	43	7	using	use	VERB
bjp-22865	43	8	phycoerythrin	phycoerythrin	NOUN
bjp-22865	43	9	(	(	PUNCT
bjp-22865	43	10	pe)-conjugated	pe)-conjugate	VERB
bjp-22865	43	11	anti	anti	NOUN
bjp-22865	43	12	-	-	NOUN
bjp-22865	43	13	thy-1	thy-1	PUNCT
bjp-22865	43	14	(	(	PUNCT
bjp-22865	43	15	cd90	cd90	PROPN
bjp-22865	43	16	)	)	PUNCT
bjp-22865	43	17	or	or	CCONJ
bjp-22865	43	18	anti	anti	ADJ
bjp-22865	43	19	-	-	ADJ
bjp-22865	43	20	cd14	cd14	PROPN
bjp-22865	43	21	and	and	CCONJ
bjp-22865	43	22	fluorescein	fluorescein	NOUN
bjp-22865	43	23	isothiocyanate	isothiocyanate	NOUN
bjp-22865	43	24	(	(	PUNCT
bjp-22865	43	25	fitc)conjugated	fitc)conjugate	VERB
bjp-22865	43	26	anti	anti	ADJ
bjp-22865	43	27	-	-	ADJ
bjp-22865	43	28	cd3	cd3	ADJ
bjp-22865	43	29	mab	mab	PROPN
bjp-22865	43	30	(	(	PUNCT
bjp-22865	43	31	bd	bd	PROPN
bjp-22865	43	32	pharmingen	pharmingen	PROPN
bjp-22865	43	33	,	,	PUNCT
bjp-22865	43	34	san	san	PROPN
bjp-22865	43	35	diego	diego	PROPN
bjp-22865	43	36	,	,	PUNCT
bjp-22865	43	37	ca	ca	NOUN
bjp-22865	43	38	)	)	PUNCT
bjp-22865	43	39	.	.	PUNCT
bjp-22865	44	1	determination	determination	NOUN
bjp-22865	44	2	of	of	ADP
bjp-22865	44	3	cell	cell	NOUN
bjp-22865	44	4	viability	viability	NOUN
bjp-22865	44	5	:	:	PUNCT
bjp-22865	44	6	cell	cell	NOUN
bjp-22865	44	7	viability	viability	NOUN
bjp-22865	44	8	of	of	ADP
bjp-22865	44	9	the	the	DET
bjp-22865	44	10	rasfs	rasfs	PROPN
bjp-22865	44	11	was	be	AUX
bjp-22865	44	12	determined	determine	VERB
bjp-22865	44	13	using	use	VERB
bjp-22865	44	14	cck-8	cck-8	X
bjp-22865	44	15	kit	kit	NOUN
bjp-22865	44	16	(	(	PUNCT
bjp-22865	44	17	dojindo	dojindo	PROPN
bjp-22865	44	18	laboratories	laboratory	NOUN
bjp-22865	44	19	,	,	PUNCT
bjp-22865	44	20	japan	japan	PROPN
bjp-22865	44	21	)	)	PUNCT
bjp-22865	44	22	.	.	PUNCT
bjp-22865	45	1	cck-8	cck-8	PUNCT
bjp-22865	45	2	kit	kit	NOUN
bjp-22865	45	3	employs	employ	VERB
bjp-22865	45	4	dojindo	dojindo	PROPN
bjp-22865	45	5	’s	’s	PART
bjp-22865	45	6	tetrazolium	tetrazolium	NOUN
bjp-22865	45	7	salt	salt	NOUN
bjp-22865	45	8	,	,	PUNCT
bjp-22865	45	9	wst-8	wst-8	PUNCT
bjp-22865	45	10	[	[	X
bjp-22865	45	11	2-(2	2-(2	NOUN
bjp-22865	45	12	-	-	PUNCT
bjp-22865	45	13	methoxy-4	methoxy-4	NUM
bjp-22865	45	14	-	-	PUNCT
bjp-22865	45	15	nitrophenyl)-3-(4	nitrophenyl)-3-(4	VERB
bjp-22865	45	16	-	-	PUNCT
bjp-22865	45	17	nitrophenyl)5-(2,4	nitrophenyl)5-(2,4	NUM
bjp-22865	45	18	-	-	PUNCT
bjp-22865	45	19	disulfophenyl)-2h	disulfophenyl)-2h	NOUN
bjp-22865	45	20	-	-	PUNCT
bjp-22865	45	21	tetrazolium	tetrazolium	NOUN
bjp-22865	45	22	,	,	PUNCT
bjp-22865	45	23	monosodium	monosodium	NOUN
bjp-22865	45	24	salt	salt	NOUN
bjp-22865	45	25	]	]	PUNCT
bjp-22865	45	26	for	for	ADP
bjp-22865	45	27	determining	determine	VERB
bjp-22865	45	28	viable	viable	ADJ
bjp-22865	45	29	cells	cell	NOUN
bjp-22865	45	30	.	.	PUNCT
bjp-22865	46	1	wst-8	wst-8	VERB
bjp-22865	46	2	in	in	ADP
bjp-22865	46	3	the	the	DET
bjp-22865	46	4	living	live	VERB
bjp-22865	46	5	cells	cell	NOUN
bjp-22865	46	6	is	be	AUX
bjp-22865	46	7	reduced	reduce	VERB
bjp-22865	46	8	by	by	ADP
bjp-22865	46	9	cellular	cellular	ADJ
bjp-22865	46	10	dehydrogenases	dehydrogenase	NOUN
bjp-22865	46	11	to	to	ADP
bjp-22865	46	12	an	an	DET
bjp-22865	46	13	orange	orange	ADJ
bjp-22865	46	14	formazan	formazan	ADJ
bjp-22865	46	15	product	product	NOUN
bjp-22865	46	16	that	that	PRON
bjp-22865	46	17	is	be	AUX
bjp-22865	46	18	directly	directly	ADV
bjp-22865	46	19	proportional	proportional	ADJ
bjp-22865	46	20	to	to	ADP
bjp-22865	46	21	the	the	DET
bjp-22865	46	22	viable	viable	ADJ
bjp-22865	46	23	cell	cell	NOUN
bjp-22865	46	24	counts	count	NOUN
bjp-22865	46	25	.	.	PUNCT
bjp-22865	47	1	briefly	briefly	ADV
bjp-22865	47	2	,	,	PUNCT
bjp-22865	47	3	rasfs	rasfs	PROPN
bjp-22865	47	4	(	(	PUNCT
bjp-22865	47	5	2	2	NUM
bjp-22865	47	6	x	x	SYM
bjp-22865	47	7	l04	l04	NOUN
bjp-22865	47	8	cells/	cells/	NUM
bjp-22865	47	9	well	well	NOUN
bjp-22865	47	10	)	)	PUNCT
bjp-22865	47	11	were	be	AUX
bjp-22865	47	12	treated	treat	VERB
bjp-22865	47	13	with	with	ADP
bjp-22865	47	14	various	various	ADJ
bjp-22865	47	15	concentrations	concentration	NOUN
bjp-22865	47	16	of	of	ADP
bjp-22865	47	17	tangeretin	tangeretin	X
bjp-22865	47	18	(	(	PUNCT
bjp-22865	47	19	50	50	NUM
bjp-22865	47	20	and	and	CCONJ
bjp-22865	47	21	100	100	NUM
bjp-22865	47	22	µm	µm	NUM
bjp-22865	47	23	)	)	PUNCT
bjp-22865	47	24	and	and	CCONJ
bjp-22865	47	25	incubated	incubate	VERB
bjp-22865	47	26	for	for	ADP
bjp-22865	47	27	24	24	NUM
bjp-22865	47	28	or	or	CCONJ
bjp-22865	47	29	48	48	NUM
bjp-22865	47	30	h	h	NOUN
bjp-22865	47	31	with	with	ADP
bjp-22865	47	32	/	/	SYM
bjp-22865	47	33	without	without	ADP
bjp-22865	47	34	il-1	il-1	X
bjp-22865	48	1	(	(	PUNCT
bjp-22865	48	2	1.0	1.0	NUM
bjp-22865	48	3	ng	ng	PROPN
bjp-22865	48	4	/	/	SYM
bjp-22865	48	5	ml	ml	NOUN
bjp-22865	48	6	)	)	PUNCT
bjp-22865	48	7	.	.	PUNCT
bjp-22865	49	1	following	follow	VERB
bjp-22865	49	2	incubation	incubation	NOUN
bjp-22865	49	3	,	,	PUNCT
bjp-22865	49	4	the	the	DET
bjp-22865	49	5	cells	cell	NOUN
bjp-22865	49	6	were	be	AUX
bjp-22865	49	7	washed	wash	VERB
bjp-22865	49	8	twice	twice	ADV
bjp-22865	49	9	with	with	ADP
bjp-22865	49	10	pbs	pbs	PROPN
bjp-22865	49	11	and	and	CCONJ
bjp-22865	49	12	cck-8	cck-8	X
bjp-22865	49	13	(	(	PUNCT
bjp-22865	49	14	20	20	NUM
bjp-22865	49	15	μl	μl	PRON
bjp-22865	49	16	)	)	PUNCT
bjp-22865	49	17	was	be	AUX
bjp-22865	49	18	added	add	VERB
bjp-22865	49	19	to	to	ADP
bjp-22865	49	20	each	each	DET
bjp-22865	49	21	well	well	ADV
bjp-22865	49	22	and	and	CCONJ
bjp-22865	49	23	incubated	incubate	VERB
bjp-22865	49	24	for	for	ADP
bjp-22865	49	25	about	about	ADV
bjp-22865	49	26	2	2	NUM
bjp-22865	49	27	-	-	SYM
bjp-22865	49	28	3	3	NUM
bjp-22865	49	29	hours	hour	NOUN
bjp-22865	49	30	.	.	PUNCT
bjp-22865	50	1	formazan	formazan	ADJ
bjp-22865	50	2	crystals	crystal	NOUN
bjp-22865	50	3	formed	form	VERB
bjp-22865	50	4	were	be	AUX
bjp-22865	50	5	dissolved	dissolve	VERB
bjp-22865	50	6	by	by	ADP
bjp-22865	50	7	adding	add	VERB
bjp-22865	50	8	dmso	dmso	NOUN
bjp-22865	50	9	(	(	PUNCT
bjp-22865	50	10	100	100	NUM
bjp-22865	50	11	µl	µl	PART
bjp-22865	50	12	/	/	SYM
bjp-22865	50	13	well	well	NOUN
bjp-22865	50	14	)	)	PUNCT
bjp-22865	50	15	.	.	PUNCT
bjp-22865	51	1	the	the	DET
bjp-22865	51	2	absorbance	absorbance	NOUN
bjp-22865	51	3	was	be	AUX
bjp-22865	51	4	read	read	VERB
bjp-22865	51	5	at	at	ADP
bjp-22865	51	6	450	450	NUM
bjp-22865	51	7	nm	nm	NOUN
bjp-22865	51	8	using	use	VERB
bjp-22865	51	9	a	a	DET
bjp-22865	51	10	microplate	microplate	NOUN
bjp-22865	51	11	reader	reader	NOUN
bjp-22865	51	12	(	(	PUNCT
bjp-22865	51	13	model	model	NOUN
bjp-22865	51	14	3550	3550	NUM
bjp-22865	51	15	,	,	PUNCT
bjp-22865	51	16	biorad	biorad	NOUN
bjp-22865	51	17	,	,	PUNCT
bjp-22865	51	18	richmond	richmond	PROPN
bjp-22865	51	19	,	,	PUNCT
bjp-22865	51	20	ca	ca	PROPN
bjp-22865	51	21	,	,	PUNCT
bjp-22865	51	22	usa	usa	PROPN
bjp-22865	51	23	)	)	PUNCT
bjp-22865	51	24	.	.	PUNCT
bjp-22865	52	1	analysis	analysis	NOUN
bjp-22865	52	2	of	of	ADP
bjp-22865	52	3	apoptosis	apoptosis	NOUN
bjp-22865	52	4	by	by	ADP
bjp-22865	52	5	annexin	annexin	NOUN
bjp-22865	52	6	v	v	ADP
bjp-22865	52	7	assay	assay	PROPN
bjp-22865	52	8	:	:	PUNCT
bjp-22865	52	9	following	follow	VERB
bjp-22865	52	10	incubation	incubation	NOUN
bjp-22865	52	11	with	with	ADP
bjp-22865	52	12	tangeretin	tangeretin	VERB
bjp-22865	52	13	with	with	ADP
bjp-22865	52	14	/	/	SYM
bjp-22865	52	15	without	without	ADP
bjp-22865	52	16	il-1	il-1	X
bjp-22865	53	1	(	(	PUNCT
bjp-22865	53	2	1.0	1.0	NUM
bjp-22865	53	3	ng/	ng/	ADJ
bjp-22865	53	4	ml	ml	NOUN
bjp-22865	53	5	)	)	PUNCT
bjp-22865	53	6	for	for	ADP
bjp-22865	53	7	24	24	NUM
bjp-22865	53	8	and	and	CCONJ
bjp-22865	53	9	48	48	NUM
bjp-22865	53	10	hours	hour	NOUN
bjp-22865	53	11	,	,	PUNCT
bjp-22865	53	12	cells	cell	NOUN
bjp-22865	53	13	were	be	AUX
bjp-22865	53	14	then	then	ADV
bjp-22865	53	15	trypsinized	trypsinize	VERB
bjp-22865	53	16	and	and	CCONJ
bjp-22865	53	17	collected	collect	VERB
bjp-22865	53	18	for	for	ADP
bjp-22865	53	19	detection	detection	NOUN
bjp-22865	53	20	of	of	ADP
bjp-22865	53	21	apoptosis	apoptosis	NOUN
bjp-22865	53	22	with	with	ADP
bjp-22865	53	23	annexin	annexin	NOUN
bjp-22865	53	24	v‑fitc	v‑fitc	PROPN
bjp-22865	53	25	apoptosis	apoptosis	NOUN
bjp-22865	53	26	detection	detection	NOUN
bjp-22865	53	27	kit	kit	NOUN
bjp-22865	53	28	(	(	PUNCT
bjp-22865	53	29	santa	santa	PROPN
bjp-22865	53	30	cruz	cruz	PROPN
bjp-22865	53	31	biotechnology	biotechnology	PROPN
bjp-22865	53	32	,	,	PUNCT
bjp-22865	53	33	santa	santa	PROPN
bjp-22865	53	34	cruz	cruz	PROPN
bjp-22865	53	35	,	,	PUNCT
bjp-22865	53	36	ca	ca	PROPN
bjp-22865	53	37	,	,	PUNCT
bjp-22865	53	38	usa	usa	PROPN
bjp-22865	53	39	)	)	PUNCT
bjp-22865	53	40	according	accord	VERB
bjp-22865	53	41	to	to	ADP
bjp-22865	53	42	the	the	DET
bjp-22865	53	43	manufacturer	manufacturer	NOUN
bjp-22865	53	44	's	's	PART
bjp-22865	53	45	instructions	instruction	NOUN
bjp-22865	53	46	.	.	PUNCT
bjp-22865	54	1	briefly	briefly	ADV
bjp-22865	54	2	,	,	PUNCT
bjp-22865	54	3	1	1	NUM
bjp-22865	54	4	×	×	NOUN
bjp-22865	54	5	106	106	NUM
bjp-22865	54	6	cells	cell	NOUN
bjp-22865	54	7	that	that	PRON
bjp-22865	54	8	were	be	AUX
bjp-22865	54	9	pretreated	pretreate	VERB
bjp-22865	54	10	with	with	ADP
bjp-22865	54	11	tangeretin	tangeretin	PROPN
bjp-22865	54	12	were	be	AUX
bjp-22865	54	13	subjected	subject	VERB
bjp-22865	54	14	to	to	ADP
bjp-22865	54	15	annexin	annexin	NOUN
bjp-22865	54	16	v	v	ADP
bjp-22865	54	17	staining	stain	VERB
bjp-22865	54	18	.	.	PUNCT
bjp-22865	55	1	the	the	DET
bjp-22865	55	2	treated	treat	VERB
bjp-22865	55	3	cells	cell	NOUN
bjp-22865	55	4	were	be	AUX
bjp-22865	55	5	washed	wash	VERB
bjp-22865	55	6	in	in	ADP
bjp-22865	55	7	pbs	pbs	PROPN
bjp-22865	55	8	,	,	PUNCT
bjp-22865	55	9	resuspended	resuspend	VERB
bjp-22865	55	10	in	in	ADP
bjp-22865	55	11	100	100	NUM
bjp-22865	55	12	μl	μl	ADP
bjp-22865	55	13	of	of	ADP
bjp-22865	55	14	binding	bind	VERB
bjp-22865	55	15	buffer	buffer	NOUN
bjp-22865	55	16	containing	contain	VERB
bjp-22865	55	17	a	a	DET
bjp-22865	55	18	fitc	fitc	NOUN
bjp-22865	55	19	-	-	PUNCT
bjp-22865	55	20	conjugated	conjugate	VERB
bjp-22865	55	21	anti	anti	ADJ
bjp-22865	55	22	-	-	ADJ
bjp-22865	55	23	annexin	annexin	NOUN
bjp-22865	55	24	v	v	ADP
bjp-22865	55	25	antibody	antibody	NOUN
bjp-22865	55	26	.	.	PUNCT
bjp-22865	56	1	the	the	DET
bjp-22865	56	2	cells	cell	NOUN
bjp-22865	56	3	were	be	AUX
bjp-22865	56	4	then	then	ADV
bjp-22865	56	5	analyzed	analyze	VERB
bjp-22865	56	6	for	for	ADP
bjp-22865	56	7	flurosence	flurosence	NOUN
bjp-22865	56	8	using	use	VERB
bjp-22865	56	9	a	a	DET
bjp-22865	56	10	flow	flow	NOUN
bjp-22865	56	11	cytometer	cytometer	NOUN
bjp-22865	56	12	(	(	PUNCT
bjp-22865	56	13	facs	facs	PROPN
bjp-22865	56	14	calibur	calibur	PROPN
bjp-22865	56	15	,	,	PUNCT
bjp-22865	56	16	bd	bd	PROPN
bjp-22865	56	17	biosciences	bioscience	NOUN
bjp-22865	56	18	)	)	PUNCT
bjp-22865	56	19	.	.	PUNCT
bjp-22865	57	1	rna	rna	NOUN
bjp-22865	57	2	isolation	isolation	NOUN
bjp-22865	57	3	and	and	CCONJ
bjp-22865	57	4	semi	semi	ADJ
bjp-22865	57	5	-	-	ADJ
bjp-22865	57	6	quantitative	quantitative	ADJ
bjp-22865	57	7	rt	rt	NOUN
bjp-22865	57	8	-	-	PUNCT
bjp-22865	57	9	pcr	pcr	NOUN
bjp-22865	57	10	:	:	PUNCT
bjp-22865	57	11	to	to	PART
bjp-22865	57	12	evaluate	evaluate	VERB
bjp-22865	57	13	the	the	DET
bjp-22865	57	14	expression	expression	NOUN
bjp-22865	57	15	of	of	ADP
bjp-22865	57	16	mmp-1	mmp-1	NOUN
bjp-22865	57	17	,	,	PUNCT
bjp-22865	57	18	mmp-3	mmp-3	NOUN
bjp-22865	57	19	,	,	PUNCT
bjp-22865	57	20	timp-1	timp-1	NUM
bjp-22865	57	21	and	and	CCONJ
bjp-22865	57	22	cox-2	cox-2	NUM
bjp-22865	57	23	mrna	mrna	PROPN
bjp-22865	57	24	,	,	PUNCT
bjp-22865	57	25	rasfs	rasfs	PROPN
bjp-22865	57	26	(	(	PUNCT
bjp-22865	57	27	1	1	NUM
bjp-22865	57	28	×	×	NOUN
bjp-22865	57	29	106	106	NUM
bjp-22865	57	30	cells	cell	NOUN
bjp-22865	57	31	)	)	PUNCT
bjp-22865	57	32	were	be	AUX
bjp-22865	57	33	cultured	cultured	ADJ
bjp-22865	57	34	for	for	ADP
bjp-22865	57	35	12	12	NUM
bjp-22865	57	36	,	,	PUNCT
bjp-22865	57	37	24	24	NUM
bjp-22865	57	38	or	or	CCONJ
bjp-22865	57	39	48	48	NUM
bjp-22865	57	40	hours	hour	NOUN
bjp-22865	57	41	with	with	ADP
bjp-22865	57	42	/	/	SYM
bjp-22865	57	43	without	without	ADP
bjp-22865	57	44	il-1	il-1	X
bjp-22865	58	1	(	(	PUNCT
bjp-22865	58	2	1.0	1.0	NUM
bjp-22865	58	3	ng	ng	PROPN
bjp-22865	58	4	/	/	SYM
bjp-22865	58	5	ml	ml	NOUN
bjp-22865	58	6	)	)	PUNCT
bjp-22865	58	7	and/or	and/or	CCONJ
bjp-22865	58	8	tangeretin	tangeretin	VERB
bjp-22865	58	9	(	(	PUNCT
bjp-22865	58	10	50	50	NUM
bjp-22865	58	11	or	or	CCONJ
bjp-22865	58	12	100	100	NUM
bjp-22865	58	13	μm	μm	NUM
bjp-22865	58	14	)	)	PUNCT
bjp-22865	58	15	.	.	PUNCT
bjp-22865	59	1	total	total	ADJ
bjp-22865	59	2	rna	rna	PROPN
bjp-22865	59	3	was	be	AUX
bjp-22865	59	4	extracted	extract	VERB
bjp-22865	59	5	from	from	ADP
bjp-22865	59	6	cultured	cultured	ADJ
bjp-22865	59	7	rasfs	rasfs	NOUN
bjp-22865	59	8	after	after	ADP
bjp-22865	59	9	incubation	incubation	NOUN
bjp-22865	59	10	with	with	ADP
bjp-22865	59	11	tangeretin	tangeretin	NOUN
bjp-22865	59	12	using	use	VERB
bjp-22865	59	13	trisol	trisol	NOUN
bjp-22865	59	14	reagent	reagent	NOUN
bjp-22865	59	15	(	(	PUNCT
bjp-22865	59	16	invitrogen	invitrogen	PROPN
bjp-22865	59	17	,	,	PUNCT
bjp-22865	59	18	carlsbad	carlsbad	PROPN
bjp-22865	59	19	,	,	PUNCT
bjp-22865	59	20	ca	ca	PROPN
bjp-22865	59	21	,	,	PUNCT
bjp-22865	59	22	usa	usa	PROPN
bjp-22865	59	23	)	)	PUNCT
bjp-22865	59	24	following	follow	VERB
bjp-22865	59	25	the	the	DET
bjp-22865	59	26	manufacturer	manufacturer	NOUN
bjp-22865	59	27	’s	’s	PART
bjp-22865	59	28	instructions	instruction	NOUN
bjp-22865	59	29	.	.	PUNCT
bjp-22865	60	1	cdna	cdna	PROPN
bjp-22865	60	2	derived	derive	VERB
bjp-22865	60	3	from	from	ADP
bjp-22865	60	4	the	the	DET
bjp-22865	60	5	reverse	reverse	ADJ
bjp-22865	60	6	transcription	transcription	NOUN
bjp-22865	60	7	of	of	ADP
bjp-22865	60	8	rna	rna	NOUN
bjp-22865	60	9	using	use	VERB
bjp-22865	60	10	maxime	maxime	PROPN
bjp-22865	60	11	rt	rt	PROPN
bjp-22865	60	12	premix	premix	PROPN
bjp-22865	60	13	kit	kit	NOUN
bjp-22865	60	14	(	(	PUNCT
bjp-22865	60	15	intron	intron	ADJ
bjp-22865	60	16	biotechnology	biotechnology	NOUN
bjp-22865	60	17	,	,	PUNCT
bjp-22865	60	18	south	south	PROPN
bjp-22865	60	19	korea	korea	PROPN
bjp-22865	60	20	)	)	PUNCT
bjp-22865	60	21	was	be	AUX
bjp-22865	60	22	amplified	amplify	VERB
bjp-22865	60	23	using	use	VERB
bjp-22865	60	24	the	the	DET
bjp-22865	60	25	following	follow	VERB
bjp-22865	60	26	primer	primer	NOUN
bjp-22865	60	27	sets	set	NOUN
bjp-22865	60	28	:	:	PUNCT
bjp-22865	60	29	timp-1	timp-1	NUM
bjp-22865	60	30	(	(	PUNCT
bjp-22865	60	31	forward	forward	ADV
bjp-22865	60	32	)	)	PUNCT
bjp-22865	60	33	5′-cct	5′-cct	PROPN
bjp-22865	60	34	tct	tct	PROPN
bjp-22865	60	35	gca	gca	PROPN
bjp-22865	60	36	att	att	PROPN
bjp-22865	60	37	ccg	ccg	PROPN
bjp-22865	60	38	acc	acc	PROPN
bjp-22865	60	39	bangladesh	bangladesh	PROPN
bjp-22865	60	40	j	j	PROPN
bjp-22865	60	41	pharmacol	pharmacol	PROPN
bjp-22865	60	42	2015	2015	NUM
bjp-22865	60	43	;	;	PUNCT
bjp-22865	60	44	10	10	NUM
bjp-22865	60	45	:	:	PUNCT
bjp-22865	60	46	714	714	NUM
bjp-22865	60	47	-	-	SYM
bjp-22865	60	48	725	725	NUM
bjp-22865	60	49	715	715	NUM
bjp-22865	60	50	tcg	tcg	NOUN
bjp-22865	60	51	tc-3′	tc-3′	NOUN
bjp-22865	60	52	(	(	PUNCT
bjp-22865	60	53	reverse	reverse	NOUN
bjp-22865	60	54	)	)	PUNCT
bjp-22865	60	55	5′-cgg	5′-cgg	NUM
bjp-22865	60	56	gca	gca	NOUN
bjp-22865	60	57	gga	gga	PROPN
bjp-22865	60	58	ttc	ttc	PROPN
bjp-22865	60	59	agg	agg	PROPN
bjp-22865	60	60	ctatct	ctatct	PROPN
bjp-22865	60	61	gg-3′	gg-3′	PROPN
bjp-22865	60	62	,	,	PUNCT
bjp-22865	60	63	mmp-1	mmp-1	PUNCT
bjp-22865	60	64	(	(	PUNCT
bjp-22865	60	65	forward	forward	ADV
bjp-22865	60	66	)	)	PUNCT
bjp-22865	60	67	5′-gaa	5′-gaa	NUM
bjp-22865	60	68	gga	gga	NOUN
bjp-22865	60	69	gat	gat	NOUN
bjp-22865	60	70	gaa	gaa	PROPN
bjp-22865	60	71	gca	gca	PROPN
bjp-22865	60	72	gcc	gcc	NOUN
bjp-22865	60	73	cag	cag	PROPN
bjp-22865	60	74	atg	atg	PROPN
bjp-22865	60	75	t-3′	t-3′	PROPN
bjp-22865	60	76	(	(	PUNCT
bjp-22865	60	77	reverse	reverse	NOUN
bjp-22865	60	78	)	)	PUNCT
bjp-22865	61	1	5′-cag	5′-cag	NUM
bjp-22865	61	2	ttg	ttg	NOUN
bjp-22865	61	3	tgg	tgg	PROPN
bjp-22865	61	4	cca	cca	PROPN
bjp-22865	61	5	gaa	gaa	PROPN
bjp-22865	61	6	aac	aac	PROPN
bjp-22865	61	7	aga	aga	PROPN
bjp-22865	61	8	agt	agt	PROPN
bjp-22865	61	9	gaa	gaa	PROPN
bjp-22865	61	10	a-3′	a-3′	PROPN
bjp-22865	61	11	,	,	PUNCT
bjp-22865	61	12	mmp-3	mmp-3	PRON
bjp-22865	61	13	(	(	PUNCT
bjp-22865	61	14	forward	forward	ADV
bjp-22865	61	15	)	)	PUNCT
bjp-22865	61	16	5′gac	5′gac	NUM
bjp-22865	61	17	acc	acc	NOUN
bjp-22865	61	18	agc	agc	PROPN
bjp-22865	61	19	atg	atg	PROPN
bjp-22865	61	20	aac	aac	PROPN
bjp-22865	61	21	ctt	ctt	PROPN
bjp-22865	61	22	gtt-3′	gtt-3′	PROPN
bjp-22865	61	23	(	(	PUNCT
bjp-22865	61	24	reverse	reverse	NOUN
bjp-22865	61	25	)	)	PUNCT
bjp-22865	61	26	5′-gga	5′-gga	NUM
bjp-22865	61	27	acc	acc	PROPN
bjp-22865	61	28	gag	gag	PROPN
bjp-22865	61	29	tca	tca	PROPN
bjp-22865	61	30	gga	gga	PROPN
bjp-22865	61	31	ctatg-3′	ctatg-3′	PROPN
bjp-22865	61	32	,	,	PUNCT
bjp-22865	61	33	cox	cox	PROPN
bjp-22865	61	34	-2	-2	INTJ
bjp-22865	61	35	(	(	PUNCT
bjp-22865	61	36	forward	forward	ADV
bjp-22865	61	37	)	)	PUNCT
bjp-22865	61	38	5′-tcc	5′-tcc	NUM
bjp-22865	61	39	ttg	ttg	NOUN
bjp-22865	61	40	ctg	ctg	VERB
bjp-22865	61	41	ttc	ttc	PROPN
bjp-22865	61	42	cca	cca	PROPN
bjp-22865	61	43	ccc	ccc	PROPN
bjp-22865	61	44	atg-3′	atg-3′	PROPN
bjp-22865	61	45	(	(	PUNCT
bjp-22865	61	46	reverse	reverse	NOUN
bjp-22865	61	47	)	)	PUNCT
bjp-22865	61	48	5′-cat	5′-cat	NUM
bjp-22865	61	49	cat	cat	NOUN
bjp-22865	62	1	cag	cag	PROPN
bjp-22865	62	2	acc	acc	PROPN
bjp-22865	62	3	agg	agg	PROPN
bjp-22865	62	4	cac	cac	PROPN
bjp-22865	62	5	cag-3′	cag-3′	PROPN
bjp-22865	62	6	,	,	PUNCT
bjp-22865	62	7	gapdh	gapdh	NOUN
bjp-22865	62	8	(	(	PUNCT
bjp-22865	62	9	forward	forward	ADV
bjp-22865	62	10	)	)	PUNCT
bjp-22865	62	11	5′-aaa	5′-aaa	NOUN
bjp-22865	62	12	tca	tca	PROPN
bjp-22865	62	13	agt	agt	PROPN
bjp-22865	62	14	ggg	ggg	NOUN
bjp-22865	62	15	gcg	gcg	PROPN
bjp-22865	62	16	atg	atg	PROPN
bjp-22865	62	17	ct-3′	ct-3′	PROPN
bjp-22865	62	18	(	(	PUNCT
bjp-22865	62	19	reverse	reverse	VERB
bjp-22865	62	20	)	)	PUNCT
bjp-22865	62	21	5′-agc	5′-agc	NOUN
bjp-22865	62	22	ttc	ttc	NOUN
bjp-22865	62	23	ccg	ccg	PROPN
bjp-22865	62	24	ttc	ttc	PROPN
bjp-22865	62	25	agc	agc	PROPN
bjp-22865	62	26	tca	tca	PROPN
bjp-22865	62	27	gg-3′.	gg-3′.	PROPN
bjp-22865	62	28	the	the	DET
bjp-22865	62	29	products	product	NOUN
bjp-22865	62	30	were	be	AUX
bjp-22865	62	31	subjected	subject	VERB
bjp-22865	62	32	to	to	ADP
bjp-22865	62	33	electrophoresis	electrophoresis	NOUN
bjp-22865	62	34	in	in	ADP
bjp-22865	62	35	1	1	NUM
bjp-22865	62	36	%	%	NOUN
bjp-22865	62	37	agarose	agarose	X
bjp-22865	62	38	gel	gel	NOUN
bjp-22865	62	39	.	.	PUNCT
bjp-22865	63	1	the	the	DET
bjp-22865	63	2	bands	band	NOUN
bjp-22865	63	3	were	be	AUX
bjp-22865	63	4	visualized	visualize	VERB
bjp-22865	63	5	by	by	ADP
bjp-22865	63	6	staining	stain	VERB
bjp-22865	63	7	with	with	ADP
bjp-22865	63	8	ethidium	ethidium	ADJ
bjp-22865	63	9	bromide	bromide	NOUN
bjp-22865	63	10	.	.	PUNCT
bjp-22865	64	1	densitometric	densitometric	ADJ
bjp-22865	64	2	analysis	analysis	NOUN
bjp-22865	64	3	was	be	AUX
bjp-22865	64	4	performed	perform	VERB
bjp-22865	64	5	on	on	ADP
bjp-22865	64	6	the	the	DET
bjp-22865	64	7	relative	relative	ADJ
bjp-22865	64	8	intensity	intensity	NOUN
bjp-22865	64	9	of	of	ADP
bjp-22865	64	10	each	each	DET
bjp-22865	64	11	band	band	NOUN
bjp-22865	64	12	(	(	PUNCT
bjp-22865	64	13	multigauge	multigauge	NOUN
bjp-22865	64	14	program	program	NOUN
bjp-22865	64	15	,	,	PUNCT
bjp-22865	64	16	version	version	NOUN
bjp-22865	64	17	3.0	3.0	NUM
bjp-22865	64	18	,	,	PUNCT
bjp-22865	64	19	fuji	fuji	PROPN
bjp-22865	64	20	film	film	PROPN
bjp-22865	64	21	,	,	PUNCT
bjp-22865	64	22	tokyo	tokyo	PROPN
bjp-22865	64	23	,	,	PUNCT
bjp-22865	64	24	japan	japan	PROPN
bjp-22865	64	25	)	)	PUNCT
bjp-22865	64	26	.	.	PUNCT
bjp-22865	65	1	western	western	ADJ
bjp-22865	65	2	blotting	blotting	NOUN
bjp-22865	65	3	:	:	PUNCT
bjp-22865	65	4	rasfs	rasfs	PROPN
bjp-22865	65	5	were	be	AUX
bjp-22865	65	6	cultured	cultured	ADJ
bjp-22865	65	7	with	with	ADP
bjp-22865	65	8	/	/	SYM
bjp-22865	65	9	without	without	ADP
bjp-22865	65	10	il1	il1	PROPN
bjp-22865	65	11	(	(	PUNCT
bjp-22865	65	12	1.0	1.0	NUM
bjp-22865	65	13	ng	ng	PROPN
bjp-22865	65	14	/	/	SYM
bjp-22865	65	15	ml	ml	NOUN
bjp-22865	65	16	)	)	PUNCT
bjp-22865	65	17	and/or	and/or	CCONJ
bjp-22865	65	18	tangeretin	tangeretin	VERB
bjp-22865	65	19	(	(	PUNCT
bjp-22865	65	20	50	50	NUM
bjp-22865	65	21	or	or	CCONJ
bjp-22865	65	22	100	100	NUM
bjp-22865	65	23	μm	μm	NUM
bjp-22865	65	24	)	)	PUNCT
bjp-22865	65	25	.	.	PUNCT
bjp-22865	66	1	rasfs	rasfs	ADJ
bjp-22865	66	2	(	(	PUNCT
bjp-22865	66	3	1	1	NUM
bjp-22865	66	4	×	×	NOUN
bjp-22865	66	5	106	106	NUM
bjp-22865	66	6	cells	cell	NOUN
bjp-22865	66	7	)	)	PUNCT
bjp-22865	66	8	were	be	AUX
bjp-22865	66	9	seeded	seed	VERB
bjp-22865	66	10	on	on	ADP
bjp-22865	66	11	100	100	NUM
bjp-22865	66	12	-	-	PUNCT
bjp-22865	66	13	mm	mm	NOUN
bjp-22865	66	14	culture	culture	NOUN
bjp-22865	66	15	dishes	dish	NOUN
bjp-22865	66	16	and	and	CCONJ
bjp-22865	66	17	harvested	harvest	VERB
bjp-22865	66	18	in	in	ADP
bjp-22865	66	19	pbs	pbs	PROPN
bjp-22865	66	20	.	.	PUNCT
bjp-22865	67	1	after	after	ADP
bjp-22865	67	2	washing	wash	VERB
bjp-22865	67	3	with	with	ADP
bjp-22865	67	4	pbs	pbs	PROPN
bjp-22865	67	5	,	,	PUNCT
bjp-22865	67	6	cell	cell	NOUN
bjp-22865	67	7	pellets	pellet	NOUN
bjp-22865	67	8	were	be	AUX
bjp-22865	67	9	lysed	lyse	VERB
bjp-22865	67	10	with	with	ADP
bjp-22865	67	11	lysis	lysis	NOUN
bjp-22865	67	12	buffer	buffer	NOUN
bjp-22865	67	13	(	(	PUNCT
bjp-22865	67	14	20	20	NUM
bjp-22865	67	15	mm	mm	PROPN
bjp-22865	67	16	hepes	hepe	NOUN
bjp-22865	67	17	,	,	PUNCT
bjp-22865	67	18	ph	ph	NOUN
bjp-22865	67	19	7.2	7.2	NUM
bjp-22865	67	20	,	,	PUNCT
bjp-22865	67	21	150	150	NUM
bjp-22865	67	22	mm	mm	NOUN
bjp-22865	67	23	nacl	nacl	NOUN
bjp-22865	67	24	,	,	PUNCT
bjp-22865	67	25	1	1	NUM
bjp-22865	67	26	%	%	NOUN
bjp-22865	67	27	triton	triton	PROPN
bjp-22865	67	28	x-100	x-100	PROPN
bjp-22865	67	29	,	,	PUNCT
bjp-22865	67	30	0.1	0.1	NUM
bjp-22865	67	31	mm	mm	PROPN
bjp-22865	67	32	phenylmethylsulfonyl	phenylmethylsulfonyl	NOUN
bjp-22865	67	33	fluoride	fluoride	NOUN
bjp-22865	67	34	,	,	PUNCT
bjp-22865	67	35	1	1	NUM
bjp-22865	67	36	μg	μg	PROPN
bjp-22865	67	37	/	/	SYM
bjp-22865	67	38	ml	ml	NOUN
bjp-22865	67	39	aprotinin	aprotinin	NOUN
bjp-22865	67	40	,	,	PUNCT
bjp-22865	67	41	1	1	NUM
bjp-22865	67	42	mm	mm	NUM
bjp-22865	67	43	edta	edta	NOUN
bjp-22865	67	44	)	)	PUNCT
bjp-22865	67	45	.	.	PUNCT
bjp-22865	68	1	after	after	ADP
bjp-22865	68	2	incubation	incubation	NOUN
bjp-22865	68	3	for	for	ADP
bjp-22865	68	4	30	30	NUM
bjp-22865	68	5	min	min	NOUN
bjp-22865	68	6	at	at	ADP
bjp-22865	68	7	4	4	NUM
bjp-22865	68	8	°	°	NOUN
bjp-22865	68	9	c	c	NOUN
bjp-22865	68	10	,	,	PUNCT
bjp-22865	68	11	cellular	cellular	ADJ
bjp-22865	68	12	debris	debris	NOUN
bjp-22865	68	13	were	be	AUX
bjp-22865	68	14	removed	remove	VERB
bjp-22865	68	15	by	by	ADP
bjp-22865	68	16	centrifugation	centrifugation	NOUN
bjp-22865	68	17	at	at	ADP
bjp-22865	68	18	100,000	100,000	NUM
bjp-22865	68	19	g	g	NOUN
bjp-22865	68	20	for	for	ADP
bjp-22865	68	21	30	30	NUM
bjp-22865	68	22	min	min	NOUN
bjp-22865	68	23	,	,	PUNCT
bjp-22865	68	24	and	and	CCONJ
bjp-22865	68	25	supernatants	supernatant	NOUN
bjp-22865	68	26	were	be	AUX
bjp-22865	68	27	analyzed	analyze	VERB
bjp-22865	68	28	by	by	ADP
bjp-22865	68	29	sds	sds	PROPN
bjp-22865	68	30	-	-	PUNCT
bjp-22865	68	31	page	page	NOUN
bjp-22865	68	32	.	.	PUNCT
bjp-22865	69	1	for	for	ADP
bjp-22865	69	2	cox-2	cox-2	NOUN
bjp-22865	69	3	immunoblotting	immunoblotte	VERB
bjp-22865	69	4	the	the	DET
bjp-22865	69	5	cell	cell	NOUN
bjp-22865	69	6	membranes	membrane	NOUN
bjp-22865	69	7	were	be	AUX
bjp-22865	69	8	prepared	prepare	VERB
bjp-22865	69	9	from	from	ADP
bjp-22865	69	10	isolated	isolate	VERB
bjp-22865	69	11	rasfs	rasfs	PROPN
bjp-22865	69	12	as	as	SCONJ
bjp-22865	69	13	described	describe	VERB
bjp-22865	69	14	previously	previously	ADV
bjp-22865	69	15	(	(	PUNCT
bjp-22865	69	16	hodgkin	hodgkin	PROPN
bjp-22865	69	17	et	et	PROPN
bjp-22865	69	18	al	al	PROPN
bjp-22865	69	19	.	.	PROPN
bjp-22865	69	20	,	,	PUNCT
bjp-22865	69	21	1990	1990	NUM
bjp-22865	69	22	)	)	PUNCT
bjp-22865	69	23	.	.	PUNCT
bjp-22865	70	1	to	to	PART
bjp-22865	70	2	determine	determine	VERB
bjp-22865	70	3	the	the	DET
bjp-22865	70	4	cytoplasmic	cytoplasmic	ADJ
bjp-22865	70	5	ikb	ikb	PROPN
bjp-22865	70	6	,	,	PUNCT
bjp-22865	70	7	cytoplasmic	cytoplasmic	ADJ
bjp-22865	70	8	extracts	extract	NOUN
bjp-22865	70	9	were	be	AUX
bjp-22865	70	10	prepared	prepare	VERB
bjp-22865	70	11	(	(	PUNCT
bjp-22865	70	12	lee	lee	PROPN
bjp-22865	70	13	et	et	PROPN
bjp-22865	70	14	al	al	PROPN
bjp-22865	70	15	.	.	PROPN
bjp-22865	70	16	,	,	PUNCT
bjp-22865	70	17	2006	2006	NUM
bjp-22865	70	18	)	)	PUNCT
bjp-22865	70	19	.	.	PUNCT
bjp-22865	71	1	to	to	PART
bjp-22865	71	2	analyze	analyze	VERB
bjp-22865	71	3	nf	nf	NOUN
bjp-22865	71	4	-	-	PUNCT
bjp-22865	71	5	kb	kb	NOUN
bjp-22865	71	6	(	(	PUNCT
bjp-22865	71	7	p65	p65	NOUN
bjp-22865	71	8	)	)	PUNCT
bjp-22865	71	9	,	,	PUNCT
bjp-22865	71	10	nuclear	nuclear	ADJ
bjp-22865	71	11	extract	extract	NOUN
bjp-22865	71	12	was	be	AUX
bjp-22865	71	13	prepared	prepare	VERB
bjp-22865	71	14	using	use	VERB
bjp-22865	71	15	a	a	DET
bjp-22865	71	16	previously	previously	ADV
bjp-22865	71	17	described	describe	VERB
bjp-22865	71	18	method	method	NOUN
bjp-22865	71	19	(	(	PUNCT
bjp-22865	71	20	lee	lee	PROPN
bjp-22865	71	21	et	et	PROPN
bjp-22865	71	22	al	al	PROPN
bjp-22865	71	23	.	.	PROPN
bjp-22865	71	24	,	,	PUNCT
bjp-22865	71	25	2006	2006	NUM
bjp-22865	71	26	)	)	PUNCT
bjp-22865	71	27	.	.	PUNCT
bjp-22865	72	1	protein	protein	NOUN
bjp-22865	72	2	concentration	concentration	NOUN
bjp-22865	72	3	was	be	AUX
bjp-22865	72	4	determined	determine	VERB
bjp-22865	72	5	by	by	ADP
bjp-22865	72	6	biorad	biorad	ADJ
bjp-22865	72	7	protein	protein	NOUN
bjp-22865	72	8	assay	assay	NOUN
bjp-22865	72	9	kit	kit	NOUN
bjp-22865	72	10	(	(	PUNCT
bjp-22865	72	11	bio	bio	NOUN
bjp-22865	72	12	-	-	ADJ
bjp-22865	72	13	rad	rad	PROPN
bjp-22865	72	14	laboratories	laboratory	NOUN
bjp-22865	72	15	,	,	PUNCT
bjp-22865	72	16	usa	usa	PROPN
bjp-22865	72	17	)	)	PUNCT
bjp-22865	72	18	.	.	PUNCT
bjp-22865	73	1	proteins	protein	NOUN
bjp-22865	73	2	were	be	AUX
bjp-22865	73	3	then	then	ADV
bjp-22865	73	4	fractionated	fractionate	VERB
bjp-22865	73	5	by	by	ADP
bjp-22865	73	6	sds	sds	PROPN
bjp-22865	73	7	-	-	PUNCT
bjp-22865	73	8	page	page	NOUN
bjp-22865	73	9	,	,	PUNCT
bjp-22865	73	10	electro	electro	PROPN
bjp-22865	73	11	transferred	transfer	VERB
bjp-22865	73	12	to	to	ADP
bjp-22865	73	13	nitrocellulose	nitrocellulose	NOUN
bjp-22865	73	14	membranes	membrane	NOUN
bjp-22865	73	15	,	,	PUNCT
bjp-22865	73	16	blotted	blot	VERB
bjp-22865	73	17	with	with	ADP
bjp-22865	73	18	respective	respective	ADJ
bjp-22865	73	19	antibodies	antibody	NOUN
bjp-22865	73	20	(	(	PUNCT
bjp-22865	73	21	mmp-1	mmp-1	NOUN
bjp-22865	73	22	,	,	PUNCT
bjp-22865	73	23	mmp-3	mmp-3	NOUN
bjp-22865	73	24	,	,	PUNCT
bjp-22865	73	25	timp	timp	NOUN
bjp-22865	73	26	,	,	PUNCT
bjp-22865	73	27	cox-2	cox-2	NOUN
bjp-22865	73	28	,	,	PUNCT
bjp-22865	73	29	erk	erk	PROPN
bjp-22865	73	30	,	,	PUNCT
bjp-22865	73	31	p	p	PROPN
bjp-22865	73	32	-	-	PUNCT
bjp-22865	73	33	erk1/2	erk1/2	NOUN
bjp-22865	73	34	,	,	PUNCT
bjp-22865	73	35	p-38	p-38	NOUN
bjp-22865	73	36	,	,	PUNCT
bjp-22865	73	37	p	p	NOUN
bjp-22865	73	38	-	-	PUNCT
bjp-22865	73	39	p38	p38	NOUN
bjp-22865	73	40	mapk	mapk	NOUN
bjp-22865	73	41	,	,	PUNCT
bjp-22865	73	42	jnk	jnk	PROPN
bjp-22865	73	43	,	,	PUNCT
bjp-22865	73	44	p	p	PROPN
bjp-22865	73	45	-	-	PUNCT
bjp-22865	73	46	jnk	jnk	PROPN
bjp-22865	73	47	,	,	PUNCT
bjp-22865	73	48	nfkb	nfkb	PROPN
bjp-22865	73	49	(	(	PUNCT
bjp-22865	73	50	p65	p65	NOUN
bjp-22865	73	51	)	)	PUNCT
bjp-22865	73	52	,	,	PUNCT
bjp-22865	73	53	ikb	ikb	ADV
bjp-22865	73	54	,	,	PUNCT
bjp-22865	73	55	and	and	CCONJ
bjp-22865	73	56	-actin	-actin	NOUN
bjp-22865	73	57	)	)	PUNCT
bjp-22865	73	58	and	and	CCONJ
bjp-22865	73	59	the	the	DET
bjp-22865	73	60	immunoreactive	immunoreactive	ADJ
bjp-22865	73	61	bands	band	NOUN
bjp-22865	73	62	were	be	AUX
bjp-22865	73	63	detected	detect	VERB
bjp-22865	73	64	by	by	ADP
bjp-22865	73	65	enhanced	enhanced	ADJ
bjp-22865	73	66	chemiluminescence	chemiluminescence	NOUN
bjp-22865	73	67	(	(	PUNCT
bjp-22865	73	68	ge	ge	PROPN
bjp-22865	73	69	healthcare	healthcare	PROPN
bjp-22865	73	70	)	)	PUNCT
bjp-22865	73	71	.	.	PUNCT
bjp-22865	74	1	assay	assay	PROPN
bjp-22865	74	2	of	of	ADP
bjp-22865	74	3	pge2	pge2	NOUN
bjp-22865	74	4	production	production	NOUN
bjp-22865	74	5	:	:	PUNCT
bjp-22865	74	6	to	to	PART
bjp-22865	74	7	analyse	analyse	VERB
bjp-22865	74	8	pge2	pge2	NOUN
bjp-22865	74	9	production	production	NOUN
bjp-22865	74	10	in	in	ADP
bjp-22865	74	11	rasfs	rasfs	PROPN
bjp-22865	74	12	,	,	PUNCT
bjp-22865	74	13	the	the	DET
bjp-22865	74	14	cells	cell	NOUN
bjp-22865	74	15	(	(	PUNCT
bjp-22865	74	16	1	1	NUM
bjp-22865	74	17	×	×	NOUN
bjp-22865	74	18	104	104	NUM
bjp-22865	74	19	cells	cell	NOUN
bjp-22865	74	20	)	)	PUNCT
bjp-22865	74	21	were	be	AUX
bjp-22865	74	22	grown	grow	VERB
bjp-22865	74	23	in	in	ADP
bjp-22865	74	24	25	25	NUM
bjp-22865	74	25	cm2	cm2	NOUN
bjp-22865	74	26	tissue	tissue	NOUN
bjp-22865	74	27	culture	culture	NOUN
bjp-22865	74	28	flasks	flask	NOUN
bjp-22865	74	29	for	for	ADP
bjp-22865	74	30	48	48	NUM
bjp-22865	74	31	hours	hour	NOUN
bjp-22865	74	32	before	before	ADP
bjp-22865	74	33	treatment	treatment	NOUN
bjp-22865	74	34	and	and	CCONJ
bjp-22865	74	35	starved	starve	VERB
bjp-22865	74	36	serum	serum	NOUN
bjp-22865	74	37	overnight	overnight	ADV
bjp-22865	74	38	before	before	ADP
bjp-22865	74	39	stimulation	stimulation	NOUN
bjp-22865	74	40	with	with	ADP
bjp-22865	74	41	il-1	il-1	PUNCT
bjp-22865	74	42	.	.	PUNCT
bjp-22865	75	1	after	after	ADP
bjp-22865	75	2	washing	wash	VERB
bjp-22865	75	3	with	with	ADP
bjp-22865	75	4	pbs	pbs	PROPN
bjp-22865	75	5	(	(	PUNCT
bjp-22865	75	6	ph	ph	NOUN
bjp-22865	75	7	7.4	7.4	NUM
bjp-22865	75	8	)	)	PUNCT
bjp-22865	75	9	,	,	PUNCT
bjp-22865	75	10	rasfs	rasfs	PROPN
bjp-22865	75	11	were	be	AUX
bjp-22865	75	12	pretreated	pretreate	VERB
bjp-22865	75	13	with	with	ADP
bjp-22865	75	14	il-1	il-1	ADP
bjp-22865	75	15	(	(	PUNCT
bjp-22865	75	16	1.0	1.0	NUM
bjp-22865	75	17	ng	ng	PROPN
bjp-22865	75	18	/	/	SYM
bjp-22865	75	19	ml	ml	NOUN
bjp-22865	75	20	)	)	PUNCT
bjp-22865	75	21	and/	and/	NOUN
bjp-22865	75	22	or	or	CCONJ
bjp-22865	75	23	tangeretin	tangeretin	ADJ
bjp-22865	75	24	(	(	PUNCT
bjp-22865	75	25	50	50	NUM
bjp-22865	75	26	or	or	CCONJ
bjp-22865	75	27	100	100	NUM
bjp-22865	75	28	μm	μm	NUM
bjp-22865	75	29	)	)	PUNCT
bjp-22865	75	30	for	for	ADP
bjp-22865	75	31	48	48	NUM
bjp-22865	75	32	hours	hour	NOUN
bjp-22865	75	33	at	at	ADP
bjp-22865	75	34	37	37	NUM
bjp-22865	75	35	°	°	ADP
bjp-22865	75	36	c	c	PROPN
bjp-22865	75	37	in	in	ADP
bjp-22865	75	38	dmem	dmem	ADJ
bjp-22865	75	39	supplemented	supplement	VERB
bjp-22865	75	40	with	with	ADP
bjp-22865	75	41	10	10	NUM
bjp-22865	75	42	%	%	NOUN
bjp-22865	75	43	(	(	PUNCT
bjp-22865	75	44	v	v	NOUN
bjp-22865	75	45	/	/	SYM
bjp-22865	75	46	v	v	NOUN
bjp-22865	75	47	)	)	PUNCT
bjp-22865	75	48	fcs	fc	NOUN
bjp-22865	75	49	in	in	ADP
bjp-22865	75	50	an	an	DET
bjp-22865	75	51	atmosphere	atmosphere	NOUN
bjp-22865	75	52	of	of	ADP
bjp-22865	75	53	5	5	NUM
bjp-22865	75	54	%	%	NOUN
bjp-22865	75	55	co2	co2	NOUN
bjp-22865	75	56	(	(	PUNCT
bjp-22865	75	57	sung	sung	NOUN
bjp-22865	75	58	et	et	PROPN
bjp-22865	75	59	al	al	PROPN
bjp-22865	75	60	.	.	PROPN
bjp-22865	75	61	,	,	PUNCT
bjp-22865	75	62	2012	2012	NUM
bjp-22865	75	63	)	)	PUNCT
bjp-22865	75	64	.	.	PUNCT
bjp-22865	76	1	the	the	DET
bjp-22865	76	2	supernatant	supernatant	NOUN
bjp-22865	76	3	was	be	AUX
bjp-22865	76	4	collected	collect	VERB
bjp-22865	76	5	after	after	ADP
bjp-22865	76	6	incubation	incubation	NOUN
bjp-22865	76	7	for	for	ADP
bjp-22865	76	8	48	48	NUM
bjp-22865	76	9	hours	hour	NOUN
bjp-22865	76	10	.	.	PUNCT
bjp-22865	77	1	the	the	DET
bjp-22865	77	2	levels	level	NOUN
bjp-22865	77	3	of	of	ADP
bjp-22865	77	4	pge2	pge2	NOUN
bjp-22865	77	5	in	in	ADP
bjp-22865	77	6	the	the	DET
bjp-22865	77	7	medium	medium	NOUN
bjp-22865	77	8	were	be	AUX
bjp-22865	77	9	determined	determine	VERB
bjp-22865	77	10	by	by	ADP
bjp-22865	77	11	elisa	elisa	PROPN
bjp-22865	77	12	kit	kit	NOUN
bjp-22865	77	13	(	(	PUNCT
bjp-22865	77	14	r&d	r&d	NOUN
bjp-22865	77	15	systems	system	NOUN
bjp-22865	77	16	,	,	PUNCT
bjp-22865	77	17	minneapolis	minneapolis	PROPN
bjp-22865	77	18	,	,	PUNCT
bjp-22865	77	19	mn	mn	PROPN
bjp-22865	77	20	,	,	PUNCT
bjp-22865	77	21	usa	usa	PROPN
bjp-22865	77	22	)	)	PUNCT
bjp-22865	77	23	.	.	PUNCT
bjp-22865	78	1	statistical	statistical	ADJ
bjp-22865	78	2	analysis	analysis	NOUN
bjp-22865	78	3	:	:	PUNCT
bjp-22865	78	4	all	all	DET
bjp-22865	78	5	data	datum	NOUN
bjp-22865	78	6	were	be	AUX
bjp-22865	78	7	expressed	express	VERB
bjp-22865	78	8	as	as	ADP
bjp-22865	78	9	the	the	DET
bjp-22865	78	10	mean	mean	ADJ
bjp-22865	78	11	±	±	PROPN
bjp-22865	78	12	sd	sd	NOUN
bjp-22865	78	13	of	of	ADP
bjp-22865	78	14	results	result	NOUN
bjp-22865	78	15	of	of	ADP
bjp-22865	78	16	three	three	NUM
bjp-22865	78	17	or	or	CCONJ
bjp-22865	78	18	six	six	NUM
bjp-22865	78	19	individual	individual	ADJ
bjp-22865	78	20	experiments	experiment	NOUN
bjp-22865	78	21	.	.	PUNCT
bjp-22865	79	1	the	the	DET
bjp-22865	79	2	data	datum	NOUN
bjp-22865	79	3	were	be	AUX
bjp-22865	79	4	analyzed	analyze	VERB
bjp-22865	79	5	using	use	VERB
bjp-22865	79	6	spss	spss	PROPN
bjp-22865	79	7	(	(	PUNCT
bjp-22865	79	8	free	free	ADJ
bjp-22865	79	9	version	version	NOUN
bjp-22865	79	10	)	)	PUNCT
bjp-22865	79	11	.	.	PUNCT
bjp-22865	80	1	group	group	NOUN
bjp-22865	80	2	mean	mean	PROPN
bjp-22865	80	3	values	value	NOUN
bjp-22865	80	4	were	be	AUX
bjp-22865	80	5	compared	compare	VERB
bjp-22865	80	6	by	by	ADP
bjp-22865	80	7	one	one	NUM
bjp-22865	80	8	-	-	PUNCT
bjp-22865	80	9	way	way	NOUN
bjp-22865	80	10	anova	anova	PROPN
bjp-22865	80	11	.	.	PUNCT
bjp-22865	81	1	the	the	DET
bjp-22865	81	2	values	value	NOUN
bjp-22865	81	3	at	at	ADP
bjp-22865	81	4	p<0.05	p<0.05	NOUN
bjp-22865	81	5	were	be	AUX
bjp-22865	81	6	considered	consider	VERB
bjp-22865	81	7	significant	significant	ADJ
bjp-22865	81	8	.	.	PUNCT
bjp-22865	82	1	results	result	NOUN
bjp-22865	82	2	tangeretin	tangeretin	VERB
bjp-22865	82	3	inhibits	inhibit	VERB
bjp-22865	82	4	il-1β	il-1β	PROPN
bjp-22865	82	5	induced	induced	ADJ
bjp-22865	82	6	proliferation	proliferation	NOUN
bjp-22865	82	7	and	and	CCONJ
bjp-22865	82	8	induces	induce	VERB
bjp-22865	82	9	apoptosis	apoptosis	NOUN
bjp-22865	82	10	of	of	ADP
bjp-22865	82	11	rasfs	rasfs	PROPN
bjp-22865	82	12	:	:	PUNCT
bjp-22865	82	13	il-1	il-1	X
bjp-22865	82	14	is	be	AUX
bjp-22865	82	15	a	a	DET
bjp-22865	82	16	well	well	ADV
bjp-22865	82	17	-	-	PUNCT
bjp-22865	82	18	known	know	VERB
bjp-22865	82	19	potent	potent	ADJ
bjp-22865	82	20	growth‑promoting	growth‑promote	VERB
bjp-22865	82	21	factor	factor	NOUN
bjp-22865	82	22	of	of	ADP
bjp-22865	82	23	synovial	synovial	ADJ
bjp-22865	82	24	fibroblasts	fibroblast	NOUN
bjp-22865	82	25	.	.	PUNCT
bjp-22865	83	1	il-1	il-1	PUNCT
bjp-22865	83	2	induced	induce	VERB
bjp-22865	83	3	the	the	DET
bjp-22865	83	4	proliferation	proliferation	NOUN
bjp-22865	83	5	of	of	ADP
bjp-22865	83	6	rasfs	rasfs	ADJ
bjp-22865	83	7	significantly	significantly	ADV
bjp-22865	83	8	(	(	PUNCT
bjp-22865	83	9	p<0.05	p<0.05	NOUN
bjp-22865	83	10	)	)	PUNCT
bjp-22865	83	11	as	as	SCONJ
bjp-22865	83	12	compared	compare	VERB
bjp-22865	83	13	with	with	ADP
bjp-22865	83	14	the	the	DET
bjp-22865	83	15	control	control	NOUN
bjp-22865	83	16	cells	cell	NOUN
bjp-22865	83	17	cultured	cultured	ADJ
bjp-22865	83	18	in	in	ADP
bjp-22865	83	19	dmso	dmso	NOUN
bjp-22865	83	20	without	without	ADP
bjp-22865	83	21	tangeretin	tangeretin	ADJ
bjp-22865	83	22	(	(	PUNCT
bjp-22865	83	23	figure	figure	NOUN
bjp-22865	83	24	1a	1a	NOUN
bjp-22865	83	25	)	)	PUNCT
bjp-22865	83	26	.	.	PUNCT
bjp-22865	84	1	exposure	exposure	NOUN
bjp-22865	84	2	to	to	PART
bjp-22865	84	3	tangeretin	tangeretin	VERB
bjp-22865	84	4	(	(	PUNCT
bjp-22865	84	5	50	50	NUM
bjp-22865	84	6	or	or	CCONJ
bjp-22865	84	7	100	100	NUM
bjp-22865	84	8	μm	μm	NUM
bjp-22865	84	9	)	)	PUNCT
bjp-22865	84	10	significantly	significantly	ADV
bjp-22865	84	11	(	(	PUNCT
bjp-22865	84	12	p<0.05	p<0.05	NOUN
bjp-22865	84	13	)	)	PUNCT
bjp-22865	84	14	inhibited	inhibit	VERB
bjp-22865	84	15	the	the	DET
bjp-22865	84	16	proliferation	proliferation	NOUN
bjp-22865	84	17	of	of	ADP
bjp-22865	84	18	rasfs	rasfs	PROPN
bjp-22865	84	19	treated	treat	VERB
bjp-22865	84	20	with	with	ADP
bjp-22865	84	21	or	or	CCONJ
bjp-22865	84	22	without	without	ADP
bjp-22865	84	23	il-1	il-1	ADP
bjp-22865	84	24	(	(	PUNCT
bjp-22865	84	25	p<0.05	p<0.05	NOUN
bjp-22865	84	26	)	)	PUNCT
bjp-22865	84	27	.	.	PUNCT
bjp-22865	85	1	the	the	DET
bjp-22865	85	2	decrease	decrease	NOUN
bjp-22865	85	3	in	in	ADP
bjp-22865	85	4	cell	cell	NOUN
bjp-22865	85	5	proliferation	proliferation	NOUN
bjp-22865	85	6	and	and	CCONJ
bjp-22865	85	7	viability	viability	NOUN
bjp-22865	85	8	was	be	AUX
bjp-22865	85	9	almost	almost	ADV
bjp-22865	85	10	multifold	multifold	ADJ
bjp-22865	85	11	as	as	SCONJ
bjp-22865	85	12	compared	compare	VERB
bjp-22865	85	13	to	to	ADP
bjp-22865	85	14	il-1	il-1	ADJ
bjp-22865	85	15	induction	induction	NOUN
bjp-22865	85	16	alone	alone	ADV
bjp-22865	85	17	.	.	PUNCT
bjp-22865	86	1	further	far	ADV
bjp-22865	86	2	,	,	PUNCT
bjp-22865	86	3	the	the	DET
bjp-22865	86	4	effects	effect	NOUN
bjp-22865	86	5	of	of	ADP
bjp-22865	86	6	tangeretin	tangeretin	NOUN
bjp-22865	86	7	on	on	ADP
bjp-22865	86	8	apoptotic	apoptotic	ADJ
bjp-22865	86	9	counts	count	NOUN
bjp-22865	86	10	of	of	ADP
bjp-22865	86	11	rasfs	rasfs	PROPN
bjp-22865	86	12	were	be	AUX
bjp-22865	86	13	examined	examine	VERB
bjp-22865	86	14	by	by	ADP
bjp-22865	86	15	flow	flow	NOUN
bjp-22865	86	16	cytometry	cytometry	NOUN
bjp-22865	86	17	.	.	PUNCT
bjp-22865	87	1	il-1	il-1	PROPN
bjp-22865	88	1	induced	induce	VERB
bjp-22865	88	2	increased	increase	VERB
bjp-22865	88	3	proliferation	proliferation	NOUN
bjp-22865	88	4	is	be	AUX
bjp-22865	88	5	accompanied	accompany	VERB
bjp-22865	88	6	with	with	ADP
bjp-22865	88	7	a	a	DET
bjp-22865	88	8	marked	mark	VERB
bjp-22865	88	9	decrease	decrease	NOUN
bjp-22865	88	10	in	in	ADP
bjp-22865	88	11	apoptotic	apoptotic	ADJ
bjp-22865	88	12	cell	cell	NOUN
bjp-22865	88	13	counts	count	NOUN
bjp-22865	88	14	.	.	PUNCT
bjp-22865	89	1	however	however	ADV
bjp-22865	89	2	,	,	PUNCT
bjp-22865	89	3	the	the	DET
bjp-22865	89	4	percentage	percentage	NOUN
bjp-22865	89	5	of	of	ADP
bjp-22865	89	6	annexin	annexin	NOUN
bjp-22865	89	7	v	v	ADP
bjp-22865	89	8	-	-	PUNCT
bjp-22865	89	9	positive	positive	ADJ
bjp-22865	89	10	cells	cell	NOUN
bjp-22865	89	11	was	be	AUX
bjp-22865	89	12	observed	observe	VERB
bjp-22865	89	13	to	to	PART
bjp-22865	89	14	be	be	AUX
bjp-22865	89	15	significantly	significantly	ADV
bjp-22865	89	16	increased	increase	VERB
bjp-22865	89	17	in	in	ADP
bjp-22865	89	18	the	the	DET
bjp-22865	89	19	rasfs	rasfs	PROPN
bjp-22865	89	20	treated	treat	VERB
bjp-22865	89	21	with	with	ADP
bjp-22865	89	22	tangeretin	tangeretin	NOUN
bjp-22865	89	23	at	at	ADP
bjp-22865	89	24	both	both	CCONJ
bjp-22865	89	25	the	the	DET
bjp-22865	89	26	doses	dose	NOUN
bjp-22865	89	27	as	as	ADP
bjp-22865	89	28	compared	compare	VERB
bjp-22865	89	29	with	with	ADP
bjp-22865	89	30	the	the	DET
bjp-22865	89	31	cells	cell	NOUN
bjp-22865	89	32	cultured	culture	VERB
bjp-22865	89	33	without	without	ADP
bjp-22865	89	34	tangeretin	tangeretin	ADJ
bjp-22865	89	35	(	(	PUNCT
bjp-22865	89	36	p<0.05	p<0.05	PROPN
bjp-22865	89	37	)	)	PUNCT
bjp-22865	89	38	(	(	PUNCT
bjp-22865	89	39	figure	figure	NOUN
bjp-22865	89	40	1b;1c	1b;1c	NUM
bjp-22865	89	41	)	)	PUNCT
bjp-22865	89	42	.	.	PUNCT
bjp-22865	90	1	tangeretin	tangeretin	VERB
bjp-22865	90	2	at	at	ADP
bjp-22865	90	3	100	100	NUM
bjp-22865	90	4	μm	μm	NOUN
bjp-22865	90	5	dose	dose	NOUN
bjp-22865	90	6	was	be	AUX
bjp-22865	90	7	observed	observe	VERB
bjp-22865	90	8	to	to	PART
bjp-22865	90	9	be	be	AUX
bjp-22865	90	10	more	more	ADV
bjp-22865	90	11	effective	effective	ADJ
bjp-22865	90	12	in	in	ADP
bjp-22865	90	13	reducing	reduce	VERB
bjp-22865	90	14	cell	cell	NOUN
bjp-22865	90	15	viability	viability	NOUN
bjp-22865	90	16	and	and	CCONJ
bjp-22865	90	17	inducing	induce	VERB
bjp-22865	90	18	apoptosis	apoptosis	NOUN
bjp-22865	90	19	than	than	ADP
bjp-22865	90	20	at	at	ADP
bjp-22865	90	21	50	50	NUM
bjp-22865	90	22	μm	μm	NOUN
bjp-22865	90	23	.	.	PUNCT
bjp-22865	91	1	effects	effect	NOUN
bjp-22865	91	2	of	of	ADP
bjp-22865	91	3	tangeretin	tangeretin	NOUN
bjp-22865	91	4	on	on	ADP
bjp-22865	91	5	il-1β	il-1β	PROPN
bjp-22865	91	6	induced	induce	VERB
bjp-22865	91	7	mmp-1	mmp-1	ADP
bjp-22865	91	8	,	,	PUNCT
bjp-22865	91	9	mmp-3	mmp-3	NUM
bjp-22865	91	10	and	and	CCONJ
bjp-22865	91	11	timp-1	timp-1	NUM
bjp-22865	91	12	mrna	mrna	NOUN
bjp-22865	91	13	expression	expression	NOUN
bjp-22865	91	14	:	:	PUNCT
bjp-22865	91	15	studies	study	NOUN
bjp-22865	91	16	have	have	AUX
bjp-22865	91	17	reported	report	VERB
bjp-22865	91	18	the	the	DET
bjp-22865	91	19	expression	expression	NOUN
bjp-22865	91	20	of	of	ADP
bjp-22865	91	21	cox2	cox2	NOUN
bjp-22865	91	22	and	and	CCONJ
bjp-22865	91	23	mmps	mmp	NOUN
bjp-22865	91	24	in	in	ADP
bjp-22865	91	25	human	human	ADJ
bjp-22865	91	26	rasfs	rasfs	PROPN
bjp-22865	91	27	is	be	AUX
bjp-22865	91	28	enhanced	enhance	VERB
bjp-22865	91	29	by	by	ADP
bjp-22865	91	30	pro	pro	ADJ
bjp-22865	91	31	-	-	ADJ
bjp-22865	91	32	inflammatory	inflammatory	ADJ
bjp-22865	91	33	cytokines	cytokine	NOUN
bjp-22865	91	34	such	such	ADJ
bjp-22865	91	35	as	as	ADP
bjp-22865	91	36	il-1	il-1	ADP
bjp-22865	91	37	(	(	PUNCT
bjp-22865	91	38	crofford	crofford	NOUN
bjp-22865	91	39	et	et	PROPN
bjp-22865	91	40	al	al	PROPN
bjp-22865	91	41	.	.	PROPN
bjp-22865	91	42	,	,	PUNCT
bjp-22865	91	43	1994	1994	NUM
bjp-22865	91	44	;	;	PUNCT
bjp-22865	91	45	tolboom	tolboom	NOUN
bjp-22865	91	46	et	et	PROPN
bjp-22865	91	47	al	al	PROPN
bjp-22865	91	48	.	.	PROPN
bjp-22865	91	49	,	,	PUNCT
bjp-22865	91	50	2002	2002	NUM
bjp-22865	91	51	)	)	PUNCT
bjp-22865	91	52	.	.	PUNCT
bjp-22865	92	1	in	in	ADP
bjp-22865	92	2	our	our	PRON
bjp-22865	92	3	study	study	NOUN
bjp-22865	92	4	to	to	PART
bjp-22865	92	5	evaluate	evaluate	VERB
bjp-22865	92	6	the	the	DET
bjp-22865	92	7	effects	effect	NOUN
bjp-22865	92	8	of	of	ADP
bjp-22865	92	9	tangeretin	tangeretin	NOUN
bjp-22865	92	10	on	on	ADP
bjp-22865	92	11	expression	expression	NOUN
bjp-22865	92	12	of	of	ADP
bjp-22865	92	13	mmp-1	mmp-1	NOUN
bjp-22865	92	14	,	,	PUNCT
bjp-22865	92	15	mmp-3	mmp-3	NUM
bjp-22865	92	16	and	and	CCONJ
bjp-22865	92	17	timp-1	timp-1	NUM
bjp-22865	92	18	genes	gene	NOUN
bjp-22865	92	19	under	under	ADP
bjp-22865	92	20	the	the	DET
bjp-22865	92	21	influence	influence	NOUN
bjp-22865	92	22	of	of	ADP
bjp-22865	92	23	il-1	il-1	X
bjp-22865	92	24	,	,	PUNCT
bjp-22865	92	25	rt	rt	PROPN
bjp-22865	92	26	-	-	PUNCT
bjp-22865	92	27	pcr	pcr	PROPN
bjp-22865	92	28	was	be	AUX
bjp-22865	92	29	performed	perform	VERB
bjp-22865	92	30	.	.	PUNCT
bjp-22865	93	1	rasfs	rasfs	PROPN
bjp-22865	93	2	were	be	AUX
bjp-22865	93	3	stimulated	stimulate	VERB
bjp-22865	93	4	with	with	ADP
bjp-22865	93	5	il-1	il-1	ADP
bjp-22865	93	6	(	(	PUNCT
bjp-22865	93	7	1.0	1.0	NUM
bjp-22865	93	8	ng	ng	PROPN
bjp-22865	93	9	/	/	SYM
bjp-22865	93	10	ml	ml	NOUN
bjp-22865	93	11	)	)	PUNCT
bjp-22865	93	12	.	.	PUNCT
bjp-22865	94	1	il‑1	il‑1	NOUN
bjp-22865	94	2	significantly	significantly	ADV
bjp-22865	94	3	(	(	PUNCT
bjp-22865	94	4	p<0.05	p<0.05	PROPN
bjp-22865	94	5	)	)	PUNCT
bjp-22865	94	6	,	,	PUNCT
bjp-22865	94	7	enhanced	enhance	VERB
bjp-22865	94	8	the	the	DET
bjp-22865	94	9	mrna	mrna	PROPN
bjp-22865	94	10	levels	level	NOUN
bjp-22865	94	11	of	of	ADP
bjp-22865	94	12	mmp‑1	mmp‑1	NOUN
bjp-22865	94	13	and	and	CCONJ
bjp-22865	94	14	mmp-3	mmp-3	PUNCT
bjp-22865	94	15	in	in	ADP
bjp-22865	94	16	rasfs	rasfs	ADJ
bjp-22865	94	17	nearly	nearly	ADV
bjp-22865	94	18	twice	twice	ADV
bjp-22865	94	19	.	.	PUNCT
bjp-22865	95	1	however	however	ADV
bjp-22865	95	2	much	much	ADJ
bjp-22865	95	3	changes	change	NOUN
bjp-22865	95	4	were	be	AUX
bjp-22865	95	5	not	not	PART
bjp-22865	95	6	observed	observe	VERB
bjp-22865	95	7	in	in	ADP
bjp-22865	95	8	timp‑1	timp‑1	NOUN
bjp-22865	95	9	mrna	mrna	PROPN
bjp-22865	95	10	levels	level	NOUN
bjp-22865	95	11	.	.	PUNCT
bjp-22865	96	1	co	co	NOUN
bjp-22865	96	2	-	-	NOUN
bjp-22865	96	3	treatment	treatment	NOUN
bjp-22865	96	4	with	with	ADP
bjp-22865	96	5	tangeretin	tangeretin	NOUN
bjp-22865	96	6	with	with	ADP
bjp-22865	96	7	il‑1	il‑1	NOUN
bjp-22865	96	8	caused	cause	VERB
bjp-22865	96	9	a	a	DET
bjp-22865	96	10	marked	mark	VERB
bjp-22865	96	11	(	(	PUNCT
bjp-22865	96	12	p<0.05	p<0.05	NOUN
bjp-22865	96	13	)	)	PUNCT
bjp-22865	96	14	decline	decline	NOUN
bjp-22865	96	15	in	in	ADP
bjp-22865	96	16	the	the	DET
bjp-22865	96	17	mrna	mrna	PROPN
bjp-22865	96	18	levels	level	NOUN
bjp-22865	96	19	of	of	ADP
bjp-22865	96	20	mmp‑1	mmp‑1	NOUN
bjp-22865	96	21	and	and	CCONJ
bjp-22865	96	22	mmp‑3	mmp‑3	NOUN
bjp-22865	96	23	(	(	PUNCT
bjp-22865	96	24	figure	figure	NOUN
bjp-22865	96	25	2	2	NUM
bjp-22865	96	26	)	)	PUNCT
bjp-22865	96	27	.	.	PUNCT
bjp-22865	97	1	the	the	DET
bjp-22865	97	2	inhibition	inhibition	NOUN
bjp-22865	97	3	of	of	ADP
bjp-22865	97	4	mrna	mrna	NOUN
bjp-22865	97	5	expression	expression	NOUN
bjp-22865	97	6	was	be	AUX
bjp-22865	97	7	more	more	ADV
bjp-22865	97	8	obvious	obvious	ADJ
bjp-22865	97	9	on	on	ADP
bjp-22865	97	10	exposure	exposure	NOUN
bjp-22865	97	11	to	to	ADP
bjp-22865	97	12	100	100	NUM
bjp-22865	97	13	μm	μm	NOUN
bjp-22865	97	14	.	.	PUNCT
bjp-22865	98	1	further	far	ADV
bjp-22865	98	2	,	,	PUNCT
bjp-22865	98	3	inhibition	inhibition	NOUN
bjp-22865	98	4	of	of	ADP
bjp-22865	98	5	the	the	DET
bjp-22865	98	6	expression	expression	NOUN
bjp-22865	98	7	of	of	ADP
bjp-22865	98	8	mmps	mmp	NOUN
bjp-22865	98	9	was	be	AUX
bjp-22865	98	10	in	in	ADP
bjp-22865	98	11	a	a	DET
bjp-22865	98	12	dosedependent	dosedependent	NOUN
bjp-22865	98	13	manner	manner	NOUN
bjp-22865	98	14	in	in	ADP
bjp-22865	98	15	both	both	CCONJ
bjp-22865	98	16	unstimulated	unstimulated	ADJ
bjp-22865	98	17	and	and	CCONJ
bjp-22865	98	18	il-1	il-1	ADP
bjp-22865	98	19	stimulated	stimulate	VERB
bjp-22865	98	20	rasfs	rasfs	PROPN
bjp-22865	98	21	,	,	PUNCT
bjp-22865	98	22	indicating	indicate	VERB
bjp-22865	98	23	the	the	DET
bjp-22865	98	24	anti	anti	ADJ
bjp-22865	98	25	-	-	ADJ
bjp-22865	98	26	inflammatory	inflammatory	ADJ
bjp-22865	98	27	potential	potential	NOUN
bjp-22865	98	28	of	of	ADP
bjp-22865	98	29	tangeretin	tangeretin	PROPN
bjp-22865	98	30	.	.	PUNCT
bjp-22865	98	31	attenuation	attenuation	NOUN
bjp-22865	98	32	of	of	ADP
bjp-22865	98	33	il-1β	il-1β	PROPN
bjp-22865	98	34	-	-	PUNCT
bjp-22865	98	35	induced	induce	VERB
bjp-22865	98	36	cox-2	cox-2	ADJ
bjp-22865	98	37	expression	expression	NOUN
bjp-22865	98	38	by	by	ADP
bjp-22865	98	39	tangeretin	tangeretin	NOUN
bjp-22865	98	40	:	:	PUNCT
bjp-22865	98	41	cox-2	cox-2	PRON
bjp-22865	98	42	is	be	AUX
bjp-22865	98	43	a	a	DET
bjp-22865	98	44	major	major	ADJ
bjp-22865	98	45	enzyme	enzyme	NOUN
bjp-22865	98	46	that	that	PRON
bjp-22865	98	47	catalyzes	catalyze	VERB
bjp-22865	98	48	the	the	DET
bjp-22865	98	49	synthesis	synthesis	NOUN
bjp-22865	98	50	of	of	ADP
bjp-22865	98	51	various	various	ADJ
bjp-22865	98	52	pgs	pgs	NOUN
bjp-22865	98	53	including	include	VERB
bjp-22865	98	54	pge2	pge2	NOUN
bjp-22865	98	55	(	(	PUNCT
bjp-22865	98	56	smith	smith	PROPN
bjp-22865	98	57	et	et	PROPN
bjp-22865	98	58	al	al	PROPN
bjp-22865	98	59	.	.	PROPN
bjp-22865	98	60	,	,	PUNCT
bjp-22865	98	61	1996	1996	NUM
bjp-22865	98	62	)	)	PUNCT
bjp-22865	98	63	.	.	PUNCT
bjp-22865	99	1	we	we	PRON
bjp-22865	99	2	determined	determine	VERB
bjp-22865	99	3	the	the	DET
bjp-22865	99	4	effect	effect	NOUN
bjp-22865	99	5	of	of	ADP
bjp-22865	99	6	tangeretin	tangeretin	VERB
bjp-22865	99	7	on	on	ADP
bjp-22865	99	8	il-1	il-1	PUNCT
bjp-22865	99	9	induced	induce	VERB
bjp-22865	99	10	cox-2	cox-2	ADJ
bjp-22865	99	11	expression	expression	NOUN
bjp-22865	99	12	in	in	ADP
bjp-22865	99	13	synovial	synovial	ADJ
bjp-22865	99	14	fibroblasts	fibroblast	NOUN
bjp-22865	99	15	.	.	PUNCT
bjp-22865	100	1	rasfs	rasfs	PROPN
bjp-22865	100	2	were	be	AUX
bjp-22865	100	3	co	co	VERB
bjp-22865	100	4	-	-	VERB
bjp-22865	100	5	treated	treat	VERB
bjp-22865	100	6	with	with	ADP
bjp-22865	100	7	1.0	1.0	NUM
bjp-22865	100	8	ng	ng	NOUN
bjp-22865	100	9	/	/	SYM
bjp-22865	100	10	ml	ml	NOUN
bjp-22865	100	11	il-1	il-1	PUNCT
bjp-22865	100	12	and/or	and/or	CCONJ
bjp-22865	100	13	tangeretin	tangeretin	VERB
bjp-22865	100	14	(	(	PUNCT
bjp-22865	100	15	50	50	NUM
bjp-22865	100	16	or	or	CCONJ
bjp-22865	100	17	100	100	NUM
bjp-22865	100	18	μm	μm	NUM
bjp-22865	100	19	)	)	PUNCT
bjp-22865	100	20	for	for	ADP
bjp-22865	100	21	12	12	NUM
bjp-22865	100	22	,	,	PUNCT
bjp-22865	100	23	24	24	NUM
bjp-22865	100	24	or	or	CCONJ
bjp-22865	100	25	48	48	NUM
bjp-22865	100	26	hours	hour	NOUN
bjp-22865	100	27	,	,	PUNCT
bjp-22865	100	28	and	and	CCONJ
bjp-22865	100	29	cox-2	cox-2	NOUN
bjp-22865	100	30	mrna	mrna	PROPN
bjp-22865	100	31	levels	level	NOUN
bjp-22865	100	32	were	be	AUX
bjp-22865	100	33	detected	detect	VERB
bjp-22865	100	34	by	by	ADP
bjp-22865	100	35	rt	rt	PROPN
bjp-22865	100	36	-	-	PUNCT
bjp-22865	100	37	pcr	pcr	NOUN
bjp-22865	100	38	.	.	PUNCT
bjp-22865	101	1	tangeretin	tangeretin	PROPN
bjp-22865	101	2	significantly	significantly	ADV
bjp-22865	101	3	attenuated	attenuate	VERB
bjp-22865	101	4	the	the	DET
bjp-22865	101	5	il-1	il-1	ADV
bjp-22865	101	6	-induced	-induce	VERB
bjp-22865	101	7	716	716	NUM
bjp-22865	101	8	bangladesh	bangladesh	NOUN
bjp-22865	101	9	j	j	PROPN
bjp-22865	101	10	pharmacol	pharmacol	PROPN
bjp-22865	101	11	2015	2015	NUM
bjp-22865	101	12	;	;	PUNCT
bjp-22865	101	13	10	10	NUM
bjp-22865	101	14	:	:	SYM
bjp-22865	101	15	714	714	NUM
bjp-22865	101	16	-	-	SYM
bjp-22865	101	17	725	725	NUM
bjp-22865	101	18	figure	figure	NOUN
bjp-22865	101	19	1	1	NUM
bjp-22865	101	20	:	:	PUNCT
bjp-22865	101	21	influence	influence	NOUN
bjp-22865	101	22	of	of	ADP
bjp-22865	101	23	tangeretin	tangeretin	VERB
bjp-22865	101	24	on	on	ADP
bjp-22865	101	25	il-1	il-1	ADP
bjp-22865	101	26	induced	induced	ADJ
bjp-22865	101	27	proliferation	proliferation	NOUN
bjp-22865	101	28	of	of	ADP
bjp-22865	101	29	rasfs	rasfs	ADJ
bjp-22865	101	30	exposure	exposure	NOUN
bjp-22865	101	31	to	to	PART
bjp-22865	101	32	tangeretin	tangeretin	VERB
bjp-22865	101	33	(	(	PUNCT
bjp-22865	101	34	50	50	NUM
bjp-22865	101	35	or	or	CCONJ
bjp-22865	101	36	100	100	NUM
bjp-22865	101	37	μm	μm	NUM
bjp-22865	101	38	)	)	PUNCT
bjp-22865	101	39	significantly	significantly	ADV
bjp-22865	101	40	(	(	PUNCT
bjp-22865	101	41	p<0.05	p<0.05	NOUN
bjp-22865	101	42	)	)	PUNCT
bjp-22865	101	43	inhibited	inhibit	VERB
bjp-22865	101	44	the	the	DET
bjp-22865	101	45	proliferation	proliferation	NOUN
bjp-22865	101	46	of	of	ADP
bjp-22865	101	47	rasfs	rasfs	NOUN
bjp-22865	101	48	in	in	ADP
bjp-22865	101	49	a	a	DET
bjp-22865	101	50	dose	dose	NOUN
bjp-22865	101	51	-	-	PUNCT
bjp-22865	101	52	dependent	dependent	ADJ
bjp-22865	101	53	manner	manner	NOUN
bjp-22865	101	54	(	(	PUNCT
bjp-22865	101	55	a	a	NOUN
bjp-22865	101	56	)	)	PUNCT
bjp-22865	101	57	and	and	CCONJ
bjp-22865	101	58	as	as	ADV
bjp-22865	101	59	well	well	ADV
bjp-22865	101	60	significantly	significantly	ADV
bjp-22865	101	61	induced	induce	VERB
bjp-22865	101	62	apoptosis	apoptosis	NOUN
bjp-22865	101	63	as	as	SCONJ
bjp-22865	101	64	seen	see	VERB
bjp-22865	101	65	by	by	ADP
bjp-22865	101	66	increased	increase	VERB
bjp-22865	101	67	apoptotic	apoptotic	ADJ
bjp-22865	101	68	cell	cell	NOUN
bjp-22865	101	69	counts	count	NOUN
bjp-22865	101	70	by	by	ADP
bjp-22865	101	71	annexin	annexin	NOUN
bjp-22865	101	72	v	v	ADP
bjp-22865	101	73	staining	stain	VERB
bjp-22865	101	74	(	(	PUNCT
bjp-22865	101	75	b	b	NOUN
bjp-22865	101	76	and	and	CCONJ
bjp-22865	101	77	c	c	NOUN
bjp-22865	101	78	)	)	PUNCT
bjp-22865	101	79	;	;	PUNCT
bjp-22865	102	1	[	[	X
bjp-22865	102	2	a	a	X
bjp-22865	102	3	-	-	PUNCT
bjp-22865	102	4	control	control	NOUN
bjp-22865	102	5	;	;	PUNCT
bjp-22865	102	6	b	b	X
bjp-22865	102	7	-	-	PUNCT
bjp-22865	102	8	il-1	il-1	PUNCT
bjp-22865	102	9	;	;	PUNCT
bjp-22865	102	10	c	c	X
bjp-22865	102	11	-	-	ADV
bjp-22865	102	12	tangeretin	tangeretin	VERB
bjp-22865	102	13	50	50	NUM
bjp-22865	102	14	µm	µm	NOUN
bjp-22865	102	15	;	;	PUNCT
bjp-22865	102	16	dtangeretin	dtangeretin	NOUN
bjp-22865	102	17	100	100	NUM
bjp-22865	102	18	µm	µm	NOUN
bjp-22865	102	19	;	;	PUNCT
bjp-22865	102	20	e	e	X
bjp-22865	102	21	-	-	PUNCT
bjp-22865	102	22	il-1	il-1	PUNCT
bjp-22865	102	23	+	+	X
bjp-22865	102	24	tangeretin	tangeretin	VERB
bjp-22865	102	25	50	50	NUM
bjp-22865	102	26	µm	µm	NOUN
bjp-22865	102	27	;	;	PUNCT
bjp-22865	102	28	f	f	X
bjp-22865	102	29	-	-	PUNCT
bjp-22865	102	30	il-1	il-1	PUNCT
bjp-22865	102	31	+	+	X
bjp-22865	102	32	tangeretin	tangeretin	VERB
bjp-22865	102	33	100	100	NUM
bjp-22865	102	34	µm	µm	NOUN
bjp-22865	102	35	]	]	PUNCT
bjp-22865	102	36	;	;	PUNCT
bjp-22865	102	37	values	value	NOUN
bjp-22865	102	38	are	be	AUX
bjp-22865	102	39	represented	represent	VERB
bjp-22865	102	40	as	as	ADP
bjp-22865	102	41	mean	mean	NOUN
bjp-22865	102	42	±	±	NUM
bjp-22865	102	43	sd	sd	NOUN
bjp-22865	102	44	;	;	PUNCT
bjp-22865	102	45	n=6	n=6	NUM
bjp-22865	102	46	;	;	PUNCT
bjp-22865	102	47	*	*	PUNCT
bjp-22865	102	48	represents	represent	VERB
bjp-22865	102	49	statistical	statistical	ADJ
bjp-22865	102	50	significance	significance	NOUN
bjp-22865	102	51	at	at	ADP
bjp-22865	102	52	p<0.05	p<0.05	NOUN
bjp-22865	102	53	compared	compare	VERB
bjp-22865	102	54	against	against	ADP
bjp-22865	102	55	control	control	NOUN
bjp-22865	102	56	as	as	SCONJ
bjp-22865	102	57	determined	determine	VERB
bjp-22865	102	58	by	by	ADP
bjp-22865	102	59	one	one	NUM
bjp-22865	102	60	-	-	PUNCT
bjp-22865	102	61	way	way	NOUN
bjp-22865	102	62	anova	anova	PROPN
bjp-22865	102	63	a	a	DET
bjp-22865	102	64	b	b	PROPN
bjp-22865	102	65	c	c	PROPN
bjp-22865	102	66	bangladesh	bangladesh	PROPN
bjp-22865	102	67	j	j	PROPN
bjp-22865	102	68	pharmacol	pharmacol	PROPN
bjp-22865	102	69	2015	2015	NUM
bjp-22865	102	70	;	;	PUNCT
bjp-22865	102	71	10	10	NUM
bjp-22865	102	72	:	:	PUNCT
bjp-22865	102	73	714	714	NUM
bjp-22865	102	74	-	-	SYM
bjp-22865	102	75	725	725	NUM
bjp-22865	102	76	717	717	NUM
bjp-22865	102	77	cox-2	cox-2	PRON
bjp-22865	102	78	mrna	mrna	NOUN
bjp-22865	102	79	expression	expression	NOUN
bjp-22865	102	80	on	on	ADP
bjp-22865	102	81	12	12	NUM
bjp-22865	102	82	,	,	PUNCT
bjp-22865	102	83	24	24	NUM
bjp-22865	102	84	or	or	CCONJ
bjp-22865	102	85	48	48	NUM
bjp-22865	102	86	hours	hour	NOUN
bjp-22865	102	87	.	.	PUNCT
bjp-22865	103	1	exposure	exposure	NOUN
bjp-22865	103	2	to	to	PART
bjp-22865	103	3	tangeretin	tangeretin	VERB
bjp-22865	103	4	at	at	ADP
bjp-22865	103	5	100	100	NUM
bjp-22865	103	6	μm	μm	NOUN
bjp-22865	103	7	caused	cause	VERB
bjp-22865	103	8	a	a	DET
bjp-22865	103	9	more	more	ADV
bjp-22865	103	10	significant	significant	ADJ
bjp-22865	103	11	inhibition	inhibition	NOUN
bjp-22865	103	12	of	of	ADP
bjp-22865	103	13	cox-2	cox-2	VERB
bjp-22865	103	14	mrna	mrna	NOUN
bjp-22865	103	15	expression	expression	NOUN
bjp-22865	103	16	.	.	PUNCT
bjp-22865	104	1	the	the	DET
bjp-22865	104	2	cells	cell	NOUN
bjp-22865	104	3	revealed	reveal	VERB
bjp-22865	104	4	a	a	DET
bjp-22865	104	5	dose	dose	NOUN
bjp-22865	104	6	-	-	PUNCT
bjp-22865	104	7	dependent	dependent	ADJ
bjp-22865	104	8	inhibitory	inhibitory	ADJ
bjp-22865	104	9	effect	effect	NOUN
bjp-22865	104	10	of	of	ADP
bjp-22865	104	11	tangeretin	tangeretin	NOUN
bjp-22865	104	12	on	on	ADP
bjp-22865	104	13	the	the	DET
bjp-22865	104	14	il-1	il-1	ADV
bjp-22865	104	15	-induced	-induce	VERB
bjp-22865	104	16	increase	increase	NOUN
bjp-22865	104	17	in	in	ADP
bjp-22865	104	18	cox-2	cox-2	ADJ
bjp-22865	104	19	mrna	mrna	PROPN
bjp-22865	104	20	levels	level	NOUN
bjp-22865	104	21	(	(	PUNCT
bjp-22865	104	22	figure	figure	NOUN
bjp-22865	104	23	2	2	NUM
bjp-22865	104	24	)	)	PUNCT
bjp-22865	104	25	.	.	PUNCT
bjp-22865	105	1	in	in	ADP
bjp-22865	105	2	addition	addition	NOUN
bjp-22865	105	3	,	,	PUNCT
bjp-22865	105	4	immunoblotting	immunoblotting	NOUN
bjp-22865	105	5	showed	show	VERB
bjp-22865	105	6	that	that	SCONJ
bjp-22865	105	7	tangeretin	tangeretin	NOUN
bjp-22865	105	8	could	could	AUX
bjp-22865	105	9	attenuate	attenuate	VERB
bjp-22865	105	10	the	the	DET
bjp-22865	105	11	il-1	il-1	ADV
bjp-22865	105	12	induced	induced	ADJ
bjp-22865	105	13	cox-2	cox-2	ADJ
bjp-22865	105	14	protein	protein	NOUN
bjp-22865	105	15	increase	increase	NOUN
bjp-22865	105	16	(	(	PUNCT
bjp-22865	105	17	p<0.05	p<0.05	NOUN
bjp-22865	105	18	)	)	PUNCT
bjp-22865	105	19	.	.	PUNCT
bjp-22865	106	1	tangeretin	tangeretin	PROPN
bjp-22865	106	2	inhibits	inhibit	VERB
bjp-22865	106	3	il-1β	il-1β	NOUN
bjp-22865	106	4	-	-	PUNCT
bjp-22865	106	5	induced	induce	VERB
bjp-22865	106	6	pge2	pge2	NOUN
bjp-22865	106	7	production	production	NOUN
bjp-22865	106	8	in	in	ADP
bjp-22865	106	9	rasfs	rasfs	PROPN
bjp-22865	106	10	:	:	PUNCT
bjp-22865	106	11	pge2	pge2	NOUN
bjp-22865	106	12	is	be	AUX
bjp-22865	106	13	a	a	DET
bjp-22865	106	14	pleiotropic	pleiotropic	ADJ
bjp-22865	106	15	mediator	mediator	NOUN
bjp-22865	106	16	of	of	ADP
bjp-22865	106	17	inflammation	inflammation	NOUN
bjp-22865	106	18	and	and	CCONJ
bjp-22865	106	19	its	its	PRON
bjp-22865	106	20	excessive	excessive	ADJ
bjp-22865	106	21	production	production	NOUN
bjp-22865	106	22	is	be	AUX
bjp-22865	106	23	associated	associate	VERB
bjp-22865	106	24	with	with	ADP
bjp-22865	106	25	many	many	ADJ
bjp-22865	106	26	pathologic	pathologic	ADJ
bjp-22865	106	27	processes	process	NOUN
bjp-22865	106	28	.	.	PUNCT
bjp-22865	107	1	pge2	pge2	NOUN
bjp-22865	107	2	plays	play	VERB
bjp-22865	107	3	a	a	DET
bjp-22865	107	4	vital	vital	ADJ
bjp-22865	107	5	role	role	NOUN
bjp-22865	107	6	in	in	ADP
bjp-22865	107	7	eliciting	elicit	VERB
bjp-22865	107	8	signs	sign	NOUN
bjp-22865	107	9	and	and	CCONJ
bjp-22865	107	10	symptoms	symptom	NOUN
bjp-22865	107	11	of	of	ADP
bjp-22865	107	12	inflammation	inflammation	NOUN
bjp-22865	107	13	(	(	PUNCT
bjp-22865	107	14	martel	martel	NOUN
bjp-22865	107	15	-	-	PUNCT
bjp-22865	107	16	pelletier	pelletier	PROPN
bjp-22865	107	17	et	et	PROPN
bjp-22865	107	18	al	al	PROPN
bjp-22865	107	19	.	.	PROPN
bjp-22865	107	20	,	,	PUNCT
bjp-22865	107	21	2004	2004	NUM
bjp-22865	107	22	)	)	PUNCT
bjp-22865	107	23	.	.	PUNCT
bjp-22865	108	1	we	we	PRON
bjp-22865	108	2	investigated	investigate	VERB
bjp-22865	108	3	the	the	DET
bjp-22865	108	4	effects	effect	NOUN
bjp-22865	108	5	of	of	ADP
bjp-22865	108	6	tangeretin	tangeretin	NOUN
bjp-22865	108	7	on	on	ADP
bjp-22865	108	8	pge2	pge2	NOUN
bjp-22865	108	9	production	production	NOUN
bjp-22865	108	10	by	by	ADP
bjp-22865	108	11	rasfs	rasfs	PROPN
bjp-22865	108	12	.	.	PUNCT
bjp-22865	109	1	rasfs	rasfs	PROPN
bjp-22865	109	2	were	be	AUX
bjp-22865	109	3	cultured	cultured	ADJ
bjp-22865	109	4	with	with	ADP
bjp-22865	109	5	il-1	il-1	ADP
bjp-22865	109	6	(	(	PUNCT
bjp-22865	109	7	1.0	1.0	NUM
bjp-22865	109	8	ng	ng	PROPN
bjp-22865	109	9	/	/	SYM
bjp-22865	109	10	ml	ml	NOUN
bjp-22865	109	11	)	)	PUNCT
bjp-22865	109	12	for	for	ADP
bjp-22865	109	13	48	48	NUM
bjp-22865	109	14	hours	hour	NOUN
bjp-22865	109	15	.	.	PUNCT
bjp-22865	110	1	a	a	DET
bjp-22865	110	2	multifold	multifold	ADJ
bjp-22865	110	3	increases	increase	NOUN
bjp-22865	110	4	in	in	ADP
bjp-22865	110	5	pge2	pge2	NOUN
bjp-22865	110	6	production	production	NOUN
bjp-22865	110	7	occurred	occur	VERB
bjp-22865	110	8	after	after	ADP
bjp-22865	110	9	il-1	il-1	ADP
bjp-22865	110	10	treatment	treatment	NOUN
bjp-22865	110	11	(	(	PUNCT
bjp-22865	110	12	p<0.05	p<0.05	NOUN
bjp-22865	110	13	)	)	PUNCT
bjp-22865	110	14	in	in	ADP
bjp-22865	110	15	comparison	comparison	NOUN
bjp-22865	110	16	to	to	ADP
bjp-22865	110	17	cells	cell	NOUN
bjp-22865	110	18	not	not	PART
bjp-22865	110	19	exposed	expose	VERB
bjp-22865	110	20	to	to	ADP
bjp-22865	110	21	il-1	il-1	X
bjp-22865	110	22	.	.	PUNCT
bjp-22865	111	1	however	however	ADV
bjp-22865	111	2	,	,	PUNCT
bjp-22865	111	3	tangeretin	tangeretin	VERB
bjp-22865	111	4	treatment	treatment	NOUN
bjp-22865	111	5	markedly	markedly	ADV
bjp-22865	111	6	inhibited	inhibit	VERB
bjp-22865	111	7	pge2	pge2	NOUN
bjp-22865	111	8	production	production	NOUN
bjp-22865	111	9	in	in	ADP
bjp-22865	111	10	a	a	DET
bjp-22865	111	11	dose	dose	NOUN
bjp-22865	111	12	-	-	PUNCT
bjp-22865	111	13	dependent	dependent	ADJ
bjp-22865	111	14	manner	manner	NOUN
bjp-22865	111	15	.	.	PUNCT
bjp-22865	112	1	the	the	DET
bjp-22865	112	2	levels	level	NOUN
bjp-22865	112	3	of	of	ADP
bjp-22865	112	4	pge2	pge2	NOUN
bjp-22865	112	5	were	be	AUX
bjp-22865	112	6	in	in	ADP
bjp-22865	112	7	line	line	NOUN
bjp-22865	112	8	with	with	ADP
bjp-22865	112	9	the	the	DET
bjp-22865	112	10	results	result	NOUN
bjp-22865	112	11	of	of	ADP
bjp-22865	112	12	cox-2	cox-2	ADJ
bjp-22865	112	13	expression	expression	NOUN
bjp-22865	112	14	,	,	PUNCT
bjp-22865	112	15	indicating	indicate	VERB
bjp-22865	112	16	that	that	SCONJ
bjp-22865	112	17	suppression	suppression	NOUN
bjp-22865	112	18	of	of	ADP
bjp-22865	112	19	cox-2	cox-2	NOUN
bjp-22865	112	20	decreased	decrease	VERB
bjp-22865	112	21	pge2	pge2	NOUN
bjp-22865	112	22	production	production	NOUN
bjp-22865	112	23	(	(	PUNCT
bjp-22865	112	24	figure	figure	NOUN
bjp-22865	112	25	3	3	NUM
bjp-22865	112	26	)	)	PUNCT
bjp-22865	112	27	.	.	PUNCT
bjp-22865	113	1	effect	effect	NOUN
bjp-22865	113	2	of	of	ADP
bjp-22865	113	3	tangeretin	tangeretin	NOUN
bjp-22865	113	4	on	on	ADP
bjp-22865	113	5	il-1β	il-1β	PROPN
bjp-22865	113	6	-	-	PUNCT
bjp-22865	113	7	induced	induce	VERB
bjp-22865	113	8	signal	signal	NOUN
bjp-22865	113	9	pathways	pathway	NOUN
bjp-22865	113	10	in	in	ADP
bjp-22865	113	11	rasfs	rasfs	PROPN
bjp-22865	113	12	:	:	PUNCT
bjp-22865	113	13	the	the	DET
bjp-22865	113	14	influence	influence	NOUN
bjp-22865	113	15	of	of	ADP
bjp-22865	113	16	tangeretin	tangeretin	NOUN
bjp-22865	113	17	on	on	ADP
bjp-22865	113	18	the	the	DET
bjp-22865	113	19	expression	expression	NOUN
bjp-22865	113	20	of	of	ADP
bjp-22865	113	21	mapk	mapk	NOUN
bjp-22865	113	22	pathway	pathway	NOUN
bjp-22865	113	23	proteins	protein	NOUN
bjp-22865	113	24	and	and	CCONJ
bjp-22865	113	25	nf	nf	ADJ
bjp-22865	113	26	κb	κb	INTJ
bjp-22865	113	27	were	be	AUX
bjp-22865	113	28	determined	determine	VERB
bjp-22865	113	29	by	by	ADP
bjp-22865	113	30	western	western	ADJ
bjp-22865	113	31	blotting	blotting	NOUN
bjp-22865	113	32	.	.	PUNCT
bjp-22865	114	1	mapk	mapk	NOUN
bjp-22865	114	2	pathway	pathway	NOUN
bjp-22865	114	3	is	be	AUX
bjp-22865	114	4	involved	involve	VERB
bjp-22865	114	5	in	in	ADP
bjp-22865	114	6	regulation	regulation	NOUN
bjp-22865	114	7	of	of	ADP
bjp-22865	114	8	cell	cell	NOUN
bjp-22865	114	9	proliferation	proliferation	NOUN
bjp-22865	114	10	,	,	PUNCT
bjp-22865	114	11	apoptosis	apoptosis	NOUN
bjp-22865	114	12	,	,	PUNCT
bjp-22865	114	13	cytokine	cytokine	ADJ
bjp-22865	114	14	expression	expression	NOUN
bjp-22865	114	15	and	and	CCONJ
bjp-22865	114	16	mmp	mmp	PROPN
bjp-22865	114	17	production	production	PROPN
bjp-22865	114	18	(	(	PUNCT
bjp-22865	114	19	kim	kim	PROPN
bjp-22865	114	20	et	et	PROPN
bjp-22865	114	21	al	al	PROPN
bjp-22865	114	22	.	.	PROPN
bjp-22865	114	23	,	,	PUNCT
bjp-22865	114	24	2006	2006	NUM
bjp-22865	114	25	)	)	PUNCT
bjp-22865	114	26	.	.	PUNCT
bjp-22865	115	1	nf‑κb	nf‑κb	PROPN
bjp-22865	115	2	and	and	CCONJ
bjp-22865	115	3	mapks	mapks	NOUN
bjp-22865	115	4	have	have	AUX
bjp-22865	115	5	been	be	AUX
bjp-22865	115	6	reported	report	VERB
bjp-22865	115	7	to	to	PART
bjp-22865	115	8	participate	participate	VERB
bjp-22865	115	9	in	in	ADP
bjp-22865	115	10	the	the	DET
bjp-22865	115	11	pathogenic	pathogenic	ADJ
bjp-22865	115	12	mechanisms	mechanism	NOUN
bjp-22865	115	13	of	of	ADP
bjp-22865	115	14	inflammation	inflammation	NOUN
bjp-22865	115	15	and	and	CCONJ
bjp-22865	115	16	the	the	DET
bjp-22865	115	17	destruction	destruction	NOUN
bjp-22865	115	18	of	of	ADP
bjp-22865	115	19	joints	joint	NOUN
bjp-22865	115	20	in	in	ADP
bjp-22865	115	21	ra	ra	PROPN
bjp-22865	115	22	.	.	PUNCT
bjp-22865	115	23	il-1	il-1	PUNCT
bjp-22865	116	1	at	at	ADP
bjp-22865	116	2	1.0	1.0	NUM
bjp-22865	116	3	ng	ng	NOUN
bjp-22865	116	4	/	/	SYM
bjp-22865	116	5	ml	ml	VERB
bjp-22865	116	6	caused	cause	VERB
bjp-22865	116	7	activation	activation	NOUN
bjp-22865	116	8	of	of	ADP
bjp-22865	116	9	the	the	DET
bjp-22865	116	10	intracellular	intracellular	ADJ
bjp-22865	116	11	mapks	mapks	NOUN
bjp-22865	116	12	including	include	VERB
bjp-22865	116	13	erk	erk	PROPN
bjp-22865	116	14	,	,	PUNCT
bjp-22865	116	15	p38	p38	NOUN
bjp-22865	116	16	,	,	PUNCT
bjp-22865	116	17	and	and	CCONJ
bjp-22865	116	18	jnk	jnk	PROPN
bjp-22865	116	19	resulting	result	VERB
bjp-22865	116	20	in	in	ADP
bjp-22865	116	21	marked	marked	ADJ
bjp-22865	116	22	increase	increase	NOUN
bjp-22865	116	23	in	in	ADP
bjp-22865	116	24	the	the	DET
bjp-22865	116	25	phosphorylation	phosphorylation	NOUN
bjp-22865	116	26	status	status	NOUN
bjp-22865	116	27	of	of	ADP
bjp-22865	116	28	these	these	DET
bjp-22865	116	29	proteins	protein	NOUN
bjp-22865	116	30	as	as	ADV
bjp-22865	116	31	well	well	ADV
bjp-22865	116	32	increase	increase	NOUN
bjp-22865	116	33	in	in	ADP
bjp-22865	116	34	mmp	mmp	PROPN
bjp-22865	116	35	levels	level	NOUN
bjp-22865	116	36	(	(	PUNCT
bjp-22865	116	37	figure	figure	VERB
bjp-22865	116	38	4	4	NUM
bjp-22865	116	39	a	a	DET
bjp-22865	116	40	-	-	PUNCT
bjp-22865	116	41	h	h	NOUN
bjp-22865	116	42	)	)	PUNCT
bjp-22865	116	43	.	.	PUNCT
bjp-22865	117	1	however	however	ADV
bjp-22865	117	2	,	,	PUNCT
bjp-22865	117	3	tangeretin	tangeretin	VERB
bjp-22865	117	4	significantly	significantly	ADV
bjp-22865	117	5	down	down	ADV
bjp-22865	117	6	-	-	PUNCT
bjp-22865	117	7	regulated	regulate	VERB
bjp-22865	117	8	il	il	PROPN
bjp-22865	117	9	1	1	NUM
bjp-22865	117	10	-induced	-induce	VERB
bjp-22865	117	11	phosphorylation	phosphorylation	NOUN
bjp-22865	117	12	of	of	ADP
bjp-22865	117	13	jnk	jnk	PROPN
bjp-22865	117	14	,	,	PUNCT
bjp-22865	117	15	erk	erk	PROPN
bjp-22865	117	16	,	,	PUNCT
bjp-22865	117	17	and	and	CCONJ
bjp-22865	117	18	p38	p38	NOUN
bjp-22865	117	19	.	.	PUNCT
bjp-22865	118	1	the	the	DET
bjp-22865	118	2	inhibition	inhibition	NOUN
bjp-22865	118	3	of	of	ADP
bjp-22865	118	4	phosphorylation	phosphorylation	NOUN
bjp-22865	118	5	by	by	ADP
bjp-22865	118	6	tangeretin	tangeretin	NOUN
bjp-22865	118	7	was	be	AUX
bjp-22865	118	8	observed	observe	VERB
bjp-22865	118	9	to	to	PART
bjp-22865	118	10	be	be	AUX
bjp-22865	118	11	time	time	NOUN
bjp-22865	118	12	and	and	CCONJ
bjp-22865	118	13	dose	dose	NOUN
bjp-22865	118	14	-	-	PUNCT
bjp-22865	118	15	dependent	dependent	ADJ
bjp-22865	118	16	.	.	PUNCT
bjp-22865	119	1	furthermore	furthermore	ADV
bjp-22865	119	2	,	,	PUNCT
bjp-22865	119	3	tangeretin	tangeretin	AUX
bjp-22865	119	4	reduced	reduce	VERB
bjp-22865	119	5	the	the	DET
bjp-22865	119	6	expressions	expression	NOUN
bjp-22865	119	7	of	of	ADP
bjp-22865	119	8	mmps	mmp	NOUN
bjp-22865	119	9	and	and	CCONJ
bjp-22865	119	10	coxfigure	coxfigure	NOUN
bjp-22865	119	11	2	2	NUM
bjp-22865	119	12	:	:	PUNCT
bjp-22865	119	13	influence	influence	NOUN
bjp-22865	119	14	of	of	ADP
bjp-22865	119	15	tangeretin	tangeretin	VERB
bjp-22865	119	16	on	on	ADP
bjp-22865	119	17	il-1	il-1	PUNCT
bjp-22865	119	18	induced	induced	ADJ
bjp-22865	119	19	mmp-1	mmp-1	ADP
bjp-22865	119	20	,	,	PUNCT
bjp-22865	119	21	mmp-3	mmp-3	NUM
bjp-22865	119	22	and	and	CCONJ
bjp-22865	119	23	timp-1	timp-1	NUM
bjp-22865	119	24	mrna	mrna	NOUN
bjp-22865	119	25	expression	expression	NOUN
bjp-22865	119	26	l1	l1	PROPN
bjp-22865	119	27	-	-	PUNCT
bjp-22865	119	28	control	control	NOUN
bjp-22865	119	29	;	;	PUNCT
bjp-22865	119	30	l2	l2	NOUN
bjp-22865	119	31	-	-	PUNCT
bjp-22865	119	32	il-1	il-1	PUNCT
bjp-22865	119	33	;	;	PUNCT
bjp-22865	119	34	l3	l3	NOUN
bjp-22865	119	35	-	-	PUNCT
bjp-22865	119	36	tangeretin	tangeretin	ADJ
bjp-22865	119	37	50	50	NUM
bjp-22865	119	38	µm	µm	NOUN
bjp-22865	119	39	;	;	PUNCT
bjp-22865	119	40	l4	l4	PROPN
bjp-22865	119	41	-	-	PUNCT
bjp-22865	119	42	tangeretin	tangeretin	NOUN
bjp-22865	119	43	100	100	NUM
bjp-22865	119	44	µm	µm	NOUN
bjp-22865	119	45	;	;	PUNCT
bjp-22865	119	46	l5	l5	PROPN
bjp-22865	119	47	-	-	PUNCT
bjp-22865	119	48	il-1	il-1	PUNCT
bjp-22865	119	49	+	+	X
bjp-22865	119	50	tangeretin	tangeretin	VERB
bjp-22865	119	51	50	50	NUM
bjp-22865	119	52	µm	µm	NOUN
bjp-22865	119	53	;	;	PUNCT
bjp-22865	119	54	l6	l6	NOUN
bjp-22865	119	55	-	-	PUNCT
bjp-22865	119	56	il-1	il-1	PUNCT
bjp-22865	119	57	+	+	X
bjp-22865	119	58	tangeretin	tangeretin	VERB
bjp-22865	119	59	100	100	NUM
bjp-22865	119	60	µm	µm	ADP
bjp-22865	119	61	figure	figure	NOUN
bjp-22865	119	62	3	3	NUM
bjp-22865	119	63	:	:	PUNCT
bjp-22865	119	64	tangeretin	tangeretin	VERB
bjp-22865	119	65	inhibits	inhibit	VERB
bjp-22865	119	66	il-1	il-1	PUNCT
bjp-22865	119	67	-induced	-induce	VERB
bjp-22865	119	68	pge2	pge2	NOUN
bjp-22865	119	69	production	production	NOUN
bjp-22865	119	70	in	in	ADP
bjp-22865	119	71	rasfs	rasfs	ADJ
bjp-22865	119	72	values	value	NOUN
bjp-22865	119	73	are	be	AUX
bjp-22865	119	74	represented	represent	VERB
bjp-22865	119	75	as	as	ADP
bjp-22865	119	76	mean	mean	NOUN
bjp-22865	119	77	±	±	NUM
bjp-22865	119	78	sd	sd	NOUN
bjp-22865	119	79	;	;	PUNCT
bjp-22865	119	80	n=6	n=6	NUM
bjp-22865	119	81	;	;	PUNCT
bjp-22865	119	82	*	*	PUNCT
bjp-22865	119	83	represents	represent	VERB
bjp-22865	119	84	statistical	statistical	ADJ
bjp-22865	119	85	significance	significance	NOUN
bjp-22865	119	86	at	at	ADP
bjp-22865	119	87	p<0.05	p<0.05	NOUN
bjp-22865	119	88	compared	compare	VERB
bjp-22865	119	89	against	against	ADP
bjp-22865	119	90	control	control	NOUN
bjp-22865	119	91	as	as	SCONJ
bjp-22865	119	92	determined	determine	VERB
bjp-22865	119	93	by	by	ADP
bjp-22865	119	94	one	one	NUM
bjp-22865	119	95	-	-	PUNCT
bjp-22865	119	96	way	way	NOUN
bjp-22865	119	97	anova	anova	PROPN
bjp-22865	119	98	718	718	NUM
bjp-22865	119	99	bangladesh	bangladesh	PROPN
bjp-22865	119	100	j	j	PROPN
bjp-22865	119	101	pharmacol	pharmacol	PROPN
bjp-22865	119	102	2015	2015	NUM
bjp-22865	119	103	;	;	PUNCT
bjp-22865	119	104	10	10	NUM
bjp-22865	119	105	:	:	PUNCT
bjp-22865	119	106	714	714	NUM
bjp-22865	119	107	-	-	SYM
bjp-22865	119	108	725	725	NUM
bjp-22865	119	109	2	2	NUM
bjp-22865	119	110	.	.	PUNCT
bjp-22865	119	111	nuclear	nuclear	ADJ
bjp-22865	119	112	translocation	translocation	NOUN
bjp-22865	119	113	and	and	CCONJ
bjp-22865	119	114	activation	activation	NOUN
bjp-22865	119	115	of	of	ADP
bjp-22865	119	116	nf	nf	NOUN
bjp-22865	119	117	-	-	PUNCT
bjp-22865	119	118	kb	kb	PROPN
bjp-22865	119	119	is	be	AUX
bjp-22865	119	120	known	know	VERB
bjp-22865	119	121	to	to	PART
bjp-22865	119	122	be	be	AUX
bjp-22865	119	123	dependent	dependent	ADJ
bjp-22865	119	124	on	on	ADP
bjp-22865	119	125	phosphorylation	phosphorylation	NOUN
bjp-22865	119	126	and	and	CCONJ
bjp-22865	119	127	subsequent	subsequent	ADJ
bjp-22865	119	128	degradation	degradation	NOUN
bjp-22865	119	129	of	of	ADP
bjp-22865	119	130	ikb	ikb	PROPN
bjp-22865	119	131	(	(	PUNCT
bjp-22865	119	132	adcock	adcock	NOUN
bjp-22865	119	133	,	,	PUNCT
bjp-22865	119	134	1997	1997	NUM
bjp-22865	119	135	)	)	PUNCT
bjp-22865	119	136	.	.	PUNCT
bjp-22865	120	1	while	while	SCONJ
bjp-22865	120	2	il-1	il-1	PUNCT
bjp-22865	120	3	caused	cause	VERB
bjp-22865	120	4	marked	marked	ADJ
bjp-22865	120	5	activation	activation	NOUN
bjp-22865	120	6	of	of	ADP
bjp-22865	120	7	nf	nf	NOUN
bjp-22865	120	8	-	-	PUNCT
bjp-22865	120	9	κb	κb	NOUN
bjp-22865	120	10	and	and	CCONJ
bjp-22865	120	11	p65	p65	NOUN
bjp-22865	120	12	,	,	PUNCT
bjp-22865	120	13	significant	significant	ADJ
bjp-22865	120	14	decrease	decrease	NOUN
bjp-22865	120	15	of	of	ADP
bjp-22865	120	16	cytoplasmic	cytoplasmic	ADJ
bjp-22865	120	17	ikb	ikb	PROPN
bjp-22865	120	18	was	be	AUX
bjp-22865	120	19	observed	observe	VERB
bjp-22865	120	20	in	in	ADP
bjp-22865	120	21	rasfs	rasfs	PROPN
bjp-22865	120	22	.	.	PUNCT
bjp-22865	121	1	nf	nf	X
bjp-22865	121	2	-	-	PUNCT
bjp-22865	121	3	κb	κb	NOUN
bjp-22865	121	4	activation	activation	NOUN
bjp-22865	121	5	was	be	AUX
bjp-22865	121	6	observably	observably	ADV
bjp-22865	121	7	inhibited	inhibit	VERB
bjp-22865	121	8	by	by	ADP
bjp-22865	121	9	tangeretin	tangeretin	VERB
bjp-22865	121	10	with	with	ADP
bjp-22865	121	11	considerable	considerable	ADJ
bjp-22865	121	12	increase	increase	NOUN
bjp-22865	121	13	in	in	ADP
bjp-22865	121	14	cytoplasmic	cytoplasmic	ADJ
bjp-22865	121	15	ikb	ikb	PROPN
bjp-22865	121	16	(	(	PUNCT
bjp-22865	121	17	figure	figure	VERB
bjp-22865	121	18	5	5	NUM
bjp-22865	121	19	a	a	NOUN
bjp-22865	121	20	-	-	PUNCT
bjp-22865	121	21	d	d	NOUN
bjp-22865	121	22	)	)	PUNCT
bjp-22865	121	23	.	.	PUNCT
bjp-22865	122	1	these	these	DET
bjp-22865	122	2	results	result	NOUN
bjp-22865	122	3	indicate	indicate	VERB
bjp-22865	122	4	that	that	DET
bjp-22865	122	5	tangefigure	tangefigure	NOUN
bjp-22865	122	6	4	4	NUM
bjp-22865	122	7	:	:	PUNCT
bjp-22865	122	8	influence	influence	NOUN
bjp-22865	122	9	of	of	ADP
bjp-22865	122	10	tangeretin	tangeretin	VERB
bjp-22865	122	11	on	on	ADP
bjp-22865	122	12	il-1	il-1	ADP
bjp-22865	122	13	-induced	-induce	VERB
bjp-22865	122	14	protein	protein	NOUN
bjp-22865	122	15	expressions	expression	NOUN
bjp-22865	122	16	tangeretin	tangeretin	VERB
bjp-22865	122	17	significantly	significantly	ADV
bjp-22865	122	18	reduced	reduce	VERB
bjp-22865	122	19	the	the	DET
bjp-22865	122	20	il-1	il-1	ADV
bjp-22865	122	21	-induced	-induce	VERB
bjp-22865	122	22	raised	raise	VERB
bjp-22865	122	23	expressions	expression	NOUN
bjp-22865	122	24	of	of	ADP
bjp-22865	122	25	mmps	mmp	NOUN
bjp-22865	122	26	and	and	CCONJ
bjp-22865	122	27	cox-2	cox-2	ADV
bjp-22865	122	28	following	follow	VERB
bjp-22865	122	29	24	24	NUM
bjp-22865	122	30	hours	hour	NOUN
bjp-22865	122	31	(	(	PUNCT
bjp-22865	122	32	a	a	PRON
bjp-22865	122	33	and	and	CCONJ
bjp-22865	122	34	c	c	NOUN
bjp-22865	122	35	)	)	PUNCT
bjp-22865	122	36	and	and	CCONJ
bjp-22865	122	37	48	48	NUM
bjp-22865	122	38	hours	hour	NOUN
bjp-22865	122	39	(	(	PUNCT
bjp-22865	122	40	b	b	NOUN
bjp-22865	122	41	and	and	CCONJ
bjp-22865	122	42	d	d	NOUN
bjp-22865	122	43	)	)	PUNCT
bjp-22865	122	44	of	of	ADP
bjp-22865	122	45	exposure	exposure	NOUN
bjp-22865	122	46	.	.	PUNCT
bjp-22865	123	1	il-1	il-1	VERB
bjp-22865	124	1	-induced	-induce	VERB
bjp-22865	124	2	marked	mark	VERB
bjp-22865	124	3	increases	increase	NOUN
bjp-22865	124	4	in	in	ADP
bjp-22865	124	5	the	the	DET
bjp-22865	124	6	phosphorylation	phosphorylation	NOUN
bjp-22865	124	7	status	status	NOUN
bjp-22865	124	8	and	and	CCONJ
bjp-22865	124	9	as	as	ADV
bjp-22865	124	10	well	well	ADV
bjp-22865	124	11	increased	increase	VERB
bjp-22865	124	12	expressions	expression	NOUN
bjp-22865	124	13	of	of	ADP
bjp-22865	124	14	mapk	mapk	NOUN
bjp-22865	124	15	pathway	pathway	NOUN
bjp-22865	124	16	proteins	protein	NOUN
bjp-22865	124	17	were	be	AUX
bjp-22865	124	18	regulated	regulate	VERB
bjp-22865	124	19	by	by	ADP
bjp-22865	124	20	tangeretin	tangeretin	VERB
bjp-22865	124	21	at	at	ADP
bjp-22865	124	22	both	both	CCONJ
bjp-22865	124	23	the	the	DET
bjp-22865	124	24	doses	dose	NOUN
bjp-22865	124	25	(	(	PUNCT
bjp-22865	124	26	50	50	NUM
bjp-22865	124	27	and	and	CCONJ
bjp-22865	124	28	100	100	NUM
bjp-22865	124	29	µm	µm	NUM
bjp-22865	124	30	)	)	PUNCT
bjp-22865	124	31	and	and	CCONJ
bjp-22865	124	32	at	at	ADP
bjp-22865	124	33	24	24	NUM
bjp-22865	124	34	hours	hour	NOUN
bjp-22865	124	35	(	(	PUNCT
bjp-22865	124	36	e	e	NOUN
bjp-22865	124	37	and	and	CCONJ
bjp-22865	124	38	g	g	NOUN
bjp-22865	124	39	)	)	PUNCT
bjp-22865	124	40	and	and	CCONJ
bjp-22865	124	41	48	48	NUM
bjp-22865	124	42	hours	hour	NOUN
bjp-22865	124	43	(	(	PUNCT
bjp-22865	124	44	f	f	NOUN
bjp-22865	124	45	and	and	CCONJ
bjp-22865	124	46	h	h	NOUN
bjp-22865	124	47	)	)	PUNCT
bjp-22865	124	48	;	;	PUNCT
bjp-22865	124	49	l1	l1	PROPN
bjp-22865	124	50	-	-	PUNCT
bjp-22865	124	51	control	control	NOUN
bjp-22865	124	52	;	;	PUNCT
bjp-22865	124	53	l2	l2	NOUN
bjp-22865	124	54	-	-	PUNCT
bjp-22865	124	55	il-1	il-1	PUNCT
bjp-22865	124	56	;	;	PUNCT
bjp-22865	124	57	l3	l3	NOUN
bjp-22865	124	58	-	-	PUNCT
bjp-22865	124	59	tangeretin	tangeretin	ADJ
bjp-22865	124	60	50	50	NUM
bjp-22865	124	61	µm	µm	NOUN
bjp-22865	124	62	;	;	PUNCT
bjp-22865	124	63	l4tangeretin	l4tangeretin	VERB
bjp-22865	124	64	100	100	NUM
bjp-22865	124	65	µm	µm	NOUN
bjp-22865	124	66	;	;	PUNCT
bjp-22865	124	67	l5	l5	PROPN
bjp-22865	124	68	-	-	PUNCT
bjp-22865	124	69	il-1	il-1	PUNCT
bjp-22865	124	70	+	+	X
bjp-22865	124	71	tangeretin	tangeretin	VERB
bjp-22865	124	72	50	50	NUM
bjp-22865	124	73	µm	µm	NOUN
bjp-22865	124	74	;	;	PUNCT
bjp-22865	124	75	l6	l6	NOUN
bjp-22865	124	76	-	-	PUNCT
bjp-22865	124	77	il-1	il-1	PUNCT
bjp-22865	124	78	+	+	X
bjp-22865	124	79	tangeretin	tangeretin	VERB
bjp-22865	124	80	100	100	NUM
bjp-22865	124	81	µm	µm	NUM
bjp-22865	124	82	;	;	PUNCT
bjp-22865	124	83	values	value	NOUN
bjp-22865	124	84	are	be	AUX
bjp-22865	124	85	represented	represent	VERB
bjp-22865	124	86	as	as	ADP
bjp-22865	124	87	mean	mean	NOUN
bjp-22865	124	88	±	±	NUM
bjp-22865	124	89	sd	sd	NOUN
bjp-22865	124	90	;	;	PUNCT
bjp-22865	124	91	n=3	n=3	NUM
bjp-22865	124	92	;	;	PUNCT
bjp-22865	124	93	*	*	PUNCT
bjp-22865	124	94	represents	represent	VERB
bjp-22865	124	95	statistical	statistical	ADJ
bjp-22865	124	96	significance	significance	NOUN
bjp-22865	124	97	at	at	ADP
bjp-22865	124	98	p<0.05	p<0.05	NOUN
bjp-22865	124	99	compared	compare	VERB
bjp-22865	124	100	against	against	ADP
bjp-22865	124	101	control	control	NOUN
bjp-22865	124	102	as	as	SCONJ
bjp-22865	124	103	determined	determine	VERB
bjp-22865	124	104	by	by	ADP
bjp-22865	124	105	one	one	NUM
bjp-22865	124	106	-	-	PUNCT
bjp-22865	124	107	way	way	NOUN
bjp-22865	124	108	anova	anova	PROPN
bjp-22865	124	109	a	a	DET
bjp-22865	124	110	b	b	PROPN
bjp-22865	124	111	c	c	PROPN
bjp-22865	124	112	bangladesh	bangladesh	PROPN
bjp-22865	124	113	j	j	PROPN
bjp-22865	124	114	pharmacol	pharmacol	PROPN
bjp-22865	124	115	2015	2015	NUM
bjp-22865	124	116	;	;	PUNCT
bjp-22865	124	117	10	10	NUM
bjp-22865	124	118	:	:	PUNCT
bjp-22865	124	119	714	714	NUM
bjp-22865	124	120	-	-	SYM
bjp-22865	124	121	725	725	NUM
bjp-22865	124	122	719	719	NUM
bjp-22865	124	123	figure	figure	NOUN
bjp-22865	124	124	4	4	NUM
bjp-22865	124	125	:	:	PUNCT
bjp-22865	124	126	influence	influence	NOUN
bjp-22865	124	127	of	of	ADP
bjp-22865	124	128	tangeretin	tangeretin	VERB
bjp-22865	124	129	on	on	ADP
bjp-22865	124	130	il-1	il-1	ADP
bjp-22865	124	131	-induced	-induce	VERB
bjp-22865	124	132	protein	protein	NOUN
bjp-22865	124	133	expressions	expression	NOUN
bjp-22865	124	134	(	(	PUNCT
bjp-22865	124	135	cont	cont	NOUN
bjp-22865	124	136	.	.	PUNCT
bjp-22865	124	137	)	)	PUNCT
bjp-22865	124	138	tangeretin	tangeretin	VERB
bjp-22865	124	139	significantly	significantly	ADV
bjp-22865	124	140	reduced	reduce	VERB
bjp-22865	124	141	the	the	DET
bjp-22865	124	142	il-1	il-1	ADV
bjp-22865	124	143	-induced	-induce	VERB
bjp-22865	124	144	raised	raise	VERB
bjp-22865	124	145	expressions	expression	NOUN
bjp-22865	124	146	of	of	ADP
bjp-22865	124	147	mmps	mmp	NOUN
bjp-22865	124	148	and	and	CCONJ
bjp-22865	124	149	cox-2	cox-2	ADV
bjp-22865	124	150	following	follow	VERB
bjp-22865	124	151	24	24	NUM
bjp-22865	124	152	hours	hour	NOUN
bjp-22865	124	153	(	(	PUNCT
bjp-22865	124	154	a	a	PRON
bjp-22865	124	155	and	and	CCONJ
bjp-22865	124	156	c	c	NOUN
bjp-22865	124	157	)	)	PUNCT
bjp-22865	124	158	and	and	CCONJ
bjp-22865	124	159	48	48	NUM
bjp-22865	124	160	hours	hour	NOUN
bjp-22865	124	161	(	(	PUNCT
bjp-22865	124	162	b	b	NOUN
bjp-22865	124	163	and	and	CCONJ
bjp-22865	124	164	d	d	NOUN
bjp-22865	124	165	)	)	PUNCT
bjp-22865	124	166	of	of	ADP
bjp-22865	124	167	exposure	exposure	NOUN
bjp-22865	124	168	.	.	PUNCT
bjp-22865	125	1	il-1	il-1	VERB
bjp-22865	126	1	-induced	-induce	VERB
bjp-22865	126	2	marked	mark	VERB
bjp-22865	126	3	increases	increase	NOUN
bjp-22865	126	4	in	in	ADP
bjp-22865	126	5	the	the	DET
bjp-22865	126	6	phosphorylation	phosphorylation	NOUN
bjp-22865	126	7	status	status	NOUN
bjp-22865	126	8	and	and	CCONJ
bjp-22865	126	9	as	as	ADV
bjp-22865	126	10	well	well	ADV
bjp-22865	126	11	increased	increase	VERB
bjp-22865	126	12	expressions	expression	NOUN
bjp-22865	126	13	of	of	ADP
bjp-22865	126	14	mapk	mapk	NOUN
bjp-22865	126	15	pathway	pathway	NOUN
bjp-22865	126	16	proteins	protein	NOUN
bjp-22865	126	17	were	be	AUX
bjp-22865	126	18	regulated	regulate	VERB
bjp-22865	126	19	by	by	ADP
bjp-22865	126	20	tangeretin	tangeretin	VERB
bjp-22865	126	21	at	at	ADP
bjp-22865	126	22	both	both	CCONJ
bjp-22865	126	23	the	the	DET
bjp-22865	126	24	doses	dose	NOUN
bjp-22865	126	25	(	(	PUNCT
bjp-22865	126	26	50	50	NUM
bjp-22865	126	27	and	and	CCONJ
bjp-22865	126	28	100	100	NUM
bjp-22865	126	29	µm	µm	NUM
bjp-22865	126	30	)	)	PUNCT
bjp-22865	126	31	and	and	CCONJ
bjp-22865	126	32	at	at	ADP
bjp-22865	126	33	24	24	NUM
bjp-22865	126	34	hours	hour	NOUN
bjp-22865	126	35	(	(	PUNCT
bjp-22865	126	36	e	e	NOUN
bjp-22865	126	37	and	and	CCONJ
bjp-22865	126	38	g	g	NOUN
bjp-22865	126	39	)	)	PUNCT
bjp-22865	126	40	and	and	CCONJ
bjp-22865	126	41	48	48	NUM
bjp-22865	126	42	hours	hour	NOUN
bjp-22865	126	43	(	(	PUNCT
bjp-22865	126	44	f	f	NOUN
bjp-22865	126	45	and	and	CCONJ
bjp-22865	126	46	h	h	NOUN
bjp-22865	126	47	)	)	PUNCT
bjp-22865	126	48	;	;	PUNCT
bjp-22865	126	49	l1	l1	PROPN
bjp-22865	126	50	-	-	PUNCT
bjp-22865	126	51	control	control	NOUN
bjp-22865	126	52	;	;	PUNCT
bjp-22865	126	53	l2	l2	NOUN
bjp-22865	126	54	-	-	PUNCT
bjp-22865	126	55	il-1	il-1	PUNCT
bjp-22865	126	56	;	;	PUNCT
bjp-22865	126	57	l3	l3	NOUN
bjp-22865	126	58	-	-	PUNCT
bjp-22865	126	59	tangeretin	tangeretin	ADJ
bjp-22865	126	60	50	50	NUM
bjp-22865	126	61	µm	µm	NOUN
bjp-22865	126	62	;	;	PUNCT
bjp-22865	126	63	l4tangeretin	l4tangeretin	VERB
bjp-22865	126	64	100	100	NUM
bjp-22865	126	65	µm	µm	NOUN
bjp-22865	126	66	;	;	PUNCT
bjp-22865	126	67	l5	l5	PROPN
bjp-22865	126	68	-	-	PUNCT
bjp-22865	126	69	il-1	il-1	PUNCT
bjp-22865	126	70	+	+	X
bjp-22865	126	71	tangeretin	tangeretin	VERB
bjp-22865	126	72	50	50	NUM
bjp-22865	126	73	µm	µm	NOUN
bjp-22865	126	74	;	;	PUNCT
bjp-22865	126	75	l6	l6	NOUN
bjp-22865	126	76	-	-	PUNCT
bjp-22865	126	77	il-1	il-1	PUNCT
bjp-22865	126	78	+	+	X
bjp-22865	126	79	tangeretin	tangeretin	VERB
bjp-22865	126	80	100	100	NUM
bjp-22865	126	81	µm	µm	NUM
bjp-22865	126	82	;	;	PUNCT
bjp-22865	126	83	values	value	NOUN
bjp-22865	126	84	are	be	AUX
bjp-22865	126	85	represented	represent	VERB
bjp-22865	126	86	as	as	ADP
bjp-22865	126	87	mean	mean	NOUN
bjp-22865	126	88	±	±	NUM
bjp-22865	126	89	sd	sd	NOUN
bjp-22865	126	90	;	;	PUNCT
bjp-22865	126	91	n=3	n=3	NUM
bjp-22865	126	92	;	;	PUNCT
bjp-22865	126	93	*	*	PUNCT
bjp-22865	126	94	represents	represent	VERB
bjp-22865	126	95	statistical	statistical	ADJ
bjp-22865	126	96	significance	significance	NOUN
bjp-22865	126	97	at	at	ADP
bjp-22865	126	98	p<0.05	p<0.05	NOUN
bjp-22865	126	99	compared	compare	VERB
bjp-22865	126	100	against	against	ADP
bjp-22865	126	101	control	control	NOUN
bjp-22865	126	102	as	as	SCONJ
bjp-22865	126	103	determined	determine	VERB
bjp-22865	126	104	by	by	ADP
bjp-22865	126	105	one	one	NUM
bjp-22865	126	106	-	-	PUNCT
bjp-22865	126	107	way	way	NOUN
bjp-22865	126	108	anova	anova	PROPN
bjp-22865	126	109	d	d	X
bjp-22865	126	110	e	e	X
bjp-22865	126	111	f	f	PROPN
bjp-22865	126	112	720	720	NUM
bjp-22865	126	113	bangladesh	bangladesh	NOUN
bjp-22865	126	114	j	j	PROPN
bjp-22865	126	115	pharmacol	pharmacol	PROPN
bjp-22865	126	116	2015	2015	NUM
bjp-22865	126	117	;	;	PUNCT
bjp-22865	126	118	10	10	NUM
bjp-22865	126	119	:	:	SYM
bjp-22865	126	120	714	714	NUM
bjp-22865	126	121	-	-	SYM
bjp-22865	126	122	725	725	NUM
bjp-22865	126	123	retin	retin	NOUN
bjp-22865	126	124	potentially	potentially	ADV
bjp-22865	126	125	inhibited	inhibit	VERB
bjp-22865	126	126	il-1	il-1	ADV
bjp-22865	126	127	-induced	-induce	VERB
bjp-22865	126	128	,	,	PUNCT
bjp-22865	126	129	expression	expression	NOUN
bjp-22865	126	130	of	of	ADP
bjp-22865	126	131	cox-2	cox-2	NOUN
bjp-22865	126	132	and	and	CCONJ
bjp-22865	126	133	regulated	regulate	VERB
bjp-22865	126	134	the	the	DET
bjp-22865	126	135	intracellular	intracellular	ADJ
bjp-22865	126	136	mapks	mapks	NOUN
bjp-22865	126	137	and	and	CCONJ
bjp-22865	126	138	nfκb	nfκb	NOUN
bjp-22865	126	139	pathways	pathway	NOUN
bjp-22865	126	140	.	.	PUNCT
bjp-22865	127	1	discussion	discussion	NOUN
bjp-22865	127	2	pathogenesis	pathogenesis	NOUN
bjp-22865	127	3	of	of	ADP
bjp-22865	127	4	ra	ra	PROPN
bjp-22865	127	5	involves	involve	VERB
bjp-22865	127	6	cellular	cellular	ADJ
bjp-22865	127	7	infiltration	infiltration	NOUN
bjp-22865	127	8	into	into	ADP
bjp-22865	127	9	the	the	DET
bjp-22865	127	10	synovium	synovium	NOUN
bjp-22865	127	11	and	and	CCONJ
bjp-22865	127	12	increase	increase	NOUN
bjp-22865	127	13	of	of	ADP
bjp-22865	127	14	inflammatory	inflammatory	ADJ
bjp-22865	127	15	cytokines	cytokine	NOUN
bjp-22865	127	16	such	such	ADJ
bjp-22865	127	17	as	as	ADP
bjp-22865	127	18	tnf	tnf	PROPN
bjp-22865	127	19	,	,	PUNCT
bjp-22865	127	20	il-1	il-1	PUNCT
bjp-22865	127	21	,	,	PUNCT
bjp-22865	127	22	and	and	CCONJ
bjp-22865	127	23	il-6	il-6	NOUN
bjp-22865	127	24	consequently	consequently	ADV
bjp-22865	127	25	leading	lead	VERB
bjp-22865	127	26	to	to	ADP
bjp-22865	127	27	cartilage	cartilage	NOUN
bjp-22865	127	28	and	and	CCONJ
bjp-22865	127	29	bone	bone	NOUN
bjp-22865	127	30	erosion	erosion	NOUN
bjp-22865	127	31	(	(	PUNCT
bjp-22865	127	32	arend	arend	PROPN
bjp-22865	127	33	,	,	PUNCT
bjp-22865	127	34	2001	2001	NUM
bjp-22865	127	35	;	;	PUNCT
bjp-22865	127	36	choy	choy	NOUN
bjp-22865	127	37	and	and	CCONJ
bjp-22865	127	38	panayi	panayi	NOUN
bjp-22865	127	39	,	,	PUNCT
bjp-22865	127	40	2001	2001	NUM
bjp-22865	127	41	;	;	PUNCT
bjp-22865	128	1	pratt	pratt	PROPN
bjp-22865	128	2	et	et	PROPN
bjp-22865	128	3	al	al	PROPN
bjp-22865	128	4	.	.	PROPN
bjp-22865	128	5	,	,	PUNCT
bjp-22865	128	6	2009	2009	NUM
bjp-22865	128	7	;	;	PUNCT
bjp-22865	128	8	choy	choy	NOUN
bjp-22865	128	9	,	,	PUNCT
bjp-22865	128	10	2012	2012	NUM
bjp-22865	128	11	)	)	PUNCT
bjp-22865	128	12	.	.	PUNCT
bjp-22865	129	1	rasfs	rasfs	PROPN
bjp-22865	129	2	play	play	VERB
bjp-22865	129	3	critical	critical	ADJ
bjp-22865	129	4	role	role	NOUN
bjp-22865	129	5	in	in	ADP
bjp-22865	129	6	the	the	DET
bjp-22865	129	7	pathogenesis	pathogenesis	NOUN
bjp-22865	129	8	of	of	ADP
bjp-22865	129	9	ra	ra	PROPN
bjp-22865	129	10	by	by	ADP
bjp-22865	129	11	involvement	involvement	NOUN
bjp-22865	129	12	in	in	ADP
bjp-22865	129	13	angiogenesis	angiogenesis	NOUN
bjp-22865	129	14	and	and	CCONJ
bjp-22865	129	15	in	in	ADP
bjp-22865	129	16	regulation	regulation	NOUN
bjp-22865	129	17	of	of	ADP
bjp-22865	129	18	the	the	DET
bjp-22865	129	19	inflammatory	inflammatory	ADJ
bjp-22865	129	20	cells	cell	NOUN
bjp-22865	129	21	(	(	PUNCT
bjp-22865	129	22	cawston	cawston	NOUN
bjp-22865	129	23	,	,	PUNCT
bjp-22865	129	24	1995	1995	NUM
bjp-22865	129	25	;	;	PUNCT
bjp-22865	129	26	han	han	PROPN
bjp-22865	129	27	et	et	PROPN
bjp-22865	129	28	al	al	PROPN
bjp-22865	129	29	.	.	PROPN
bjp-22865	129	30	,	,	PUNCT
bjp-22865	129	31	2003	2003	NUM
bjp-22865	129	32	)	)	PUNCT
bjp-22865	129	33	.	.	PUNCT
bjp-22865	130	1	strategies	strategy	NOUN
bjp-22865	130	2	that	that	PRON
bjp-22865	130	3	aim	aim	VERB
bjp-22865	130	4	in	in	ADP
bjp-22865	130	5	blocking	block	VERB
bjp-22865	130	6	either	either	CCONJ
bjp-22865	130	7	the	the	DET
bjp-22865	130	8	proliferation	proliferation	NOUN
bjp-22865	130	9	of	of	ADP
bjp-22865	130	10	rasfs	rasfs	NOUN
bjp-22865	130	11	or	or	CCONJ
bjp-22865	130	12	production	production	NOUN
bjp-22865	130	13	of	of	ADP
bjp-22865	130	14	the	the	DET
bjp-22865	130	15	inflammatory	inflammatory	ADJ
bjp-22865	130	16	mediators	mediator	NOUN
bjp-22865	130	17	are	be	AUX
bjp-22865	130	18	possible	possible	ADJ
bjp-22865	130	19	means	mean	NOUN
bjp-22865	130	20	of	of	ADP
bjp-22865	130	21	therapy	therapy	NOUN
bjp-22865	130	22	against	against	ADP
bjp-22865	130	23	ra	ra	PROPN
bjp-22865	130	24	.	.	PUNCT
bjp-22865	131	1	in	in	ADP
bjp-22865	131	2	our	our	PRON
bjp-22865	131	3	study	study	NOUN
bjp-22865	131	4	,	,	PUNCT
bjp-22865	131	5	tangeretin	tangeretin	VERB
bjp-22865	131	6	potentially	potentially	ADV
bjp-22865	131	7	reduced	reduce	VERB
bjp-22865	131	8	the	the	DET
bjp-22865	131	9	proliferation	proliferation	NOUN
bjp-22865	131	10	of	of	ADP
bjp-22865	131	11	rasfs	rasfs	NOUN
bjp-22865	131	12	and	and	CCONJ
bjp-22865	131	13	also	also	ADV
bjp-22865	131	14	raised	raise	VERB
bjp-22865	131	15	the	the	DET
bjp-22865	131	16	apoptotic	apoptotic	ADJ
bjp-22865	131	17	cell	cell	NOUN
bjp-22865	131	18	counts	count	NOUN
bjp-22865	131	19	.	.	PUNCT
bjp-22865	132	1	the	the	DET
bjp-22865	132	2	aggressive	aggressive	ADJ
bjp-22865	132	3	proliferation	proliferation	NOUN
bjp-22865	132	4	of	of	ADP
bjp-22865	132	5	rasfs	rasfs	NOUN
bjp-22865	132	6	is	be	AUX
bjp-22865	132	7	the	the	DET
bjp-22865	132	8	main	main	ADJ
bjp-22865	132	9	mechanism	mechanism	NOUN
bjp-22865	132	10	for	for	ADP
bjp-22865	132	11	the	the	DET
bjp-22865	132	12	hyperplasic	hyperplasic	ADJ
bjp-22865	132	13	growth	growth	NOUN
bjp-22865	132	14	of	of	ADP
bjp-22865	132	15	the	the	DET
bjp-22865	132	16	ra	ra	PROPN
bjp-22865	132	17	synovium	synovium	NOUN
bjp-22865	132	18	.	.	PUNCT
bjp-22865	133	1	cytokine	cytokine	NOUN
bjp-22865	133	2	-il-1	-il-1	PUNCT
bjp-22865	133	3	induces	induce	VERB
bjp-22865	133	4	the	the	DET
bjp-22865	133	5	proliferation	proliferation	NOUN
bjp-22865	133	6	of	of	ADP
bjp-22865	133	7	rasfs	rasfs	NOUN
bjp-22865	133	8	and	and	CCONJ
bjp-22865	133	9	plays	play	VERB
bjp-22865	133	10	an	an	DET
bjp-22865	133	11	vital	vital	ADJ
bjp-22865	133	12	role	role	NOUN
bjp-22865	133	13	in	in	ADP
bjp-22865	133	14	the	the	DET
bjp-22865	133	15	pathogenesis	pathogenesis	NOUN
bjp-22865	133	16	of	of	ADP
bjp-22865	133	17	inflammatory	inflammatory	ADJ
bjp-22865	133	18	synovitis	synovitis	NOUN
bjp-22865	133	19	and	and	CCONJ
bjp-22865	133	20	joint	joint	ADJ
bjp-22865	133	21	destruction	destruction	NOUN
bjp-22865	133	22	(	(	PUNCT
bjp-22865	133	23	gitter	gitter	PROPN
bjp-22865	133	24	et	et	PROPN
bjp-22865	133	25	al	al	PROPN
bjp-22865	133	26	.	.	PROPN
bjp-22865	133	27	,	,	PUNCT
bjp-22865	133	28	1989	1989	NUM
bjp-22865	133	29	;	;	PUNCT
bjp-22865	133	30	williams	williams	PROPN
bjp-22865	133	31	et	et	PROPN
bjp-22865	133	32	al	al	PROPN
bjp-22865	133	33	.	.	PROPN
bjp-22865	133	34	2007	2007	NUM
bjp-22865	133	35	;	;	PUNCT
bjp-22865	133	36	tanida	tanida	PROPN
bjp-22865	133	37	et	et	PROPN
bjp-22865	133	38	al	al	PROPN
bjp-22865	133	39	.	.	PROPN
bjp-22865	133	40	,	,	PUNCT
bjp-22865	133	41	2009	2009	NUM
bjp-22865	133	42	;	;	PUNCT
bjp-22865	133	43	choy	choy	NOUN
bjp-22865	133	44	,	,	PUNCT
bjp-22865	133	45	2012	2012	NUM
bjp-22865	133	46	)	)	PUNCT
bjp-22865	133	47	.	.	PUNCT
bjp-22865	134	1	the	the	DET
bjp-22865	134	2	results	result	NOUN
bjp-22865	134	3	indicate	indicate	VERB
bjp-22865	134	4	that	that	PRON
bjp-22865	134	5	tangeretin	tangeretin	X
bjp-22865	134	6	(	(	PUNCT
bjp-22865	134	7	50	50	NUM
bjp-22865	134	8	and	and	CCONJ
bjp-22865	134	9	100	100	NUM
bjp-22865	134	10	µm	µm	NOUN
bjp-22865	134	11	)	)	PUNCT
bjp-22865	134	12	significantly	significantly	ADV
bjp-22865	134	13	inhibits	inhibit	VERB
bjp-22865	134	14	il-1	il-1	PUNCT
bjp-22865	134	15	-induced	-induce	VERB
bjp-22865	134	16	proliferation	proliferation	NOUN
bjp-22865	134	17	of	of	ADP
bjp-22865	134	18	rasfs	rasfs	NOUN
bjp-22865	134	19	in	in	ADP
bjp-22865	134	20	a	a	DET
bjp-22865	134	21	doseand	doseand	ADJ
bjp-22865	134	22	time	time	NOUN
bjp-22865	134	23	-	-	PUNCT
bjp-22865	134	24	dependent	dependent	ADJ
bjp-22865	134	25	manner	manner	NOUN
bjp-22865	134	26	.	.	PUNCT
bjp-22865	135	1	further	far	ADV
bjp-22865	135	2	tangeretin	tangeretin	PROPN
bjp-22865	135	3	was	be	AUX
bjp-22865	135	4	also	also	ADV
bjp-22865	135	5	able	able	ADJ
bjp-22865	135	6	to	to	PART
bjp-22865	135	7	reduce	reduce	VERB
bjp-22865	135	8	proliferation	proliferation	NOUN
bjp-22865	135	9	of	of	ADP
bjp-22865	135	10	synovial	synovial	ADJ
bjp-22865	135	11	fibroblasts	fibroblast	NOUN
bjp-22865	135	12	not	not	PART
bjp-22865	135	13	exposed	expose	VERB
bjp-22865	135	14	to	to	ADP
bjp-22865	135	15	il-1	il-1	ADP
bjp-22865	135	16	as	as	ADV
bjp-22865	135	17	well	well	ADV
bjp-22865	135	18	.	.	PUNCT
bjp-22865	136	1	studies	study	NOUN
bjp-22865	136	2	have	have	AUX
bjp-22865	136	3	shown	show	VERB
bjp-22865	136	4	that	that	SCONJ
bjp-22865	136	5	pro	pro	ADJ
bjp-22865	136	6	-	-	ADJ
bjp-22865	136	7	inflammatory	inflammatory	ADJ
bjp-22865	136	8	cytokines	cytokine	NOUN
bjp-22865	136	9	including	include	VERB
bjp-22865	136	10	il-1	il-1	NUM
bjp-22865	136	11	could	could	AUX
bjp-22865	136	12	enhance	enhance	VERB
bjp-22865	136	13	the	the	DET
bjp-22865	136	14	expression	expression	NOUN
bjp-22865	136	15	of	of	ADP
bjp-22865	136	16	cox‑2	cox‑2	NOUN
bjp-22865	136	17	and	and	CCONJ
bjp-22865	136	18	mmps	mmp	NOUN
bjp-22865	136	19	in	in	ADP
bjp-22865	136	20	human	human	ADJ
bjp-22865	136	21	rasfs	rasfs	PROPN
bjp-22865	136	22	(	(	PUNCT
bjp-22865	136	23	tolboom	tolboom	NOUN
bjp-22865	136	24	et	et	PROPN
bjp-22865	136	25	al	al	PROPN
bjp-22865	136	26	.	.	PROPN
bjp-22865	136	27	,	,	PUNCT
bjp-22865	136	28	2002	2002	NUM
bjp-22865	136	29	)	)	PUNCT
bjp-22865	136	30	.	.	PUNCT
bjp-22865	137	1	mmps	mmp	NOUN
bjp-22865	137	2	play	play	VERB
bjp-22865	137	3	a	a	DET
bjp-22865	137	4	key	key	ADJ
bjp-22865	137	5	role	role	NOUN
bjp-22865	137	6	in	in	ADP
bjp-22865	137	7	the	the	DET
bjp-22865	137	8	destruction	destruction	NOUN
bjp-22865	137	9	of	of	ADP
bjp-22865	137	10	the	the	DET
bjp-22865	137	11	figure	figure	NOUN
bjp-22865	137	12	4	4	NUM
bjp-22865	137	13	:	:	PUNCT
bjp-22865	137	14	influence	influence	NOUN
bjp-22865	137	15	of	of	ADP
bjp-22865	137	16	tangeretin	tangeretin	VERB
bjp-22865	137	17	on	on	ADP
bjp-22865	137	18	il-1	il-1	ADP
bjp-22865	137	19	-induced	-induce	VERB
bjp-22865	137	20	protein	protein	NOUN
bjp-22865	137	21	expressions	expression	NOUN
bjp-22865	137	22	(	(	PUNCT
bjp-22865	137	23	cont	cont	NOUN
bjp-22865	137	24	.	.	PUNCT
bjp-22865	137	25	)	)	PUNCT
bjp-22865	138	1	tangeretin	tangeretin	VERB
bjp-22865	138	2	significantly	significantly	ADV
bjp-22865	138	3	reduced	reduce	VERB
bjp-22865	138	4	the	the	DET
bjp-22865	138	5	il-1	il-1	ADV
bjp-22865	138	6	-induced	-induce	VERB
bjp-22865	138	7	raised	raise	VERB
bjp-22865	138	8	expressions	expression	NOUN
bjp-22865	138	9	of	of	ADP
bjp-22865	138	10	mmps	mmp	NOUN
bjp-22865	138	11	and	and	CCONJ
bjp-22865	138	12	cox-2	cox-2	ADV
bjp-22865	138	13	following	follow	VERB
bjp-22865	138	14	24	24	NUM
bjp-22865	138	15	hours	hour	NOUN
bjp-22865	138	16	(	(	PUNCT
bjp-22865	138	17	a	a	PRON
bjp-22865	138	18	and	and	CCONJ
bjp-22865	138	19	c	c	NOUN
bjp-22865	138	20	)	)	PUNCT
bjp-22865	138	21	and	and	CCONJ
bjp-22865	138	22	48	48	NUM
bjp-22865	138	23	hours	hour	NOUN
bjp-22865	138	24	(	(	PUNCT
bjp-22865	138	25	b	b	NOUN
bjp-22865	138	26	and	and	CCONJ
bjp-22865	138	27	d	d	NOUN
bjp-22865	138	28	)	)	PUNCT
bjp-22865	138	29	of	of	ADP
bjp-22865	138	30	exposure	exposure	NOUN
bjp-22865	138	31	.	.	PUNCT
bjp-22865	139	1	il-1	il-1	VERB
bjp-22865	140	1	-induced	-induce	VERB
bjp-22865	140	2	marked	mark	VERB
bjp-22865	140	3	increases	increase	NOUN
bjp-22865	140	4	in	in	ADP
bjp-22865	140	5	the	the	DET
bjp-22865	140	6	phosphorylation	phosphorylation	NOUN
bjp-22865	140	7	status	status	NOUN
bjp-22865	140	8	and	and	CCONJ
bjp-22865	140	9	as	as	ADV
bjp-22865	140	10	well	well	ADV
bjp-22865	140	11	increased	increase	VERB
bjp-22865	140	12	expressions	expression	NOUN
bjp-22865	140	13	of	of	ADP
bjp-22865	140	14	mapk	mapk	NOUN
bjp-22865	140	15	pathway	pathway	NOUN
bjp-22865	140	16	proteins	protein	NOUN
bjp-22865	140	17	were	be	AUX
bjp-22865	140	18	regulated	regulate	VERB
bjp-22865	140	19	by	by	ADP
bjp-22865	140	20	tangeretin	tangeretin	VERB
bjp-22865	140	21	at	at	ADP
bjp-22865	140	22	both	both	CCONJ
bjp-22865	140	23	the	the	DET
bjp-22865	140	24	doses	dose	NOUN
bjp-22865	140	25	(	(	PUNCT
bjp-22865	140	26	50	50	NUM
bjp-22865	140	27	and	and	CCONJ
bjp-22865	140	28	100	100	NUM
bjp-22865	140	29	µm	µm	NUM
bjp-22865	140	30	)	)	PUNCT
bjp-22865	140	31	and	and	CCONJ
bjp-22865	140	32	at	at	ADP
bjp-22865	140	33	24	24	NUM
bjp-22865	140	34	hours	hour	NOUN
bjp-22865	140	35	(	(	PUNCT
bjp-22865	140	36	e	e	NOUN
bjp-22865	140	37	and	and	CCONJ
bjp-22865	140	38	g	g	NOUN
bjp-22865	140	39	)	)	PUNCT
bjp-22865	140	40	and	and	CCONJ
bjp-22865	140	41	48	48	NUM
bjp-22865	140	42	hours	hour	NOUN
bjp-22865	140	43	(	(	PUNCT
bjp-22865	140	44	f	f	NOUN
bjp-22865	140	45	and	and	CCONJ
bjp-22865	140	46	h	h	NOUN
bjp-22865	140	47	)	)	PUNCT
bjp-22865	140	48	;	;	PUNCT
bjp-22865	140	49	l1	l1	PROPN
bjp-22865	140	50	-	-	PUNCT
bjp-22865	140	51	control	control	NOUN
bjp-22865	140	52	;	;	PUNCT
bjp-22865	140	53	l2	l2	NOUN
bjp-22865	140	54	-	-	PUNCT
bjp-22865	140	55	il-1	il-1	PUNCT
bjp-22865	140	56	;	;	PUNCT
bjp-22865	140	57	l3	l3	NOUN
bjp-22865	140	58	-	-	PUNCT
bjp-22865	140	59	tangeretin	tangeretin	ADJ
bjp-22865	140	60	50	50	NUM
bjp-22865	140	61	µm	µm	NOUN
bjp-22865	140	62	;	;	PUNCT
bjp-22865	140	63	l4tangeretin	l4tangeretin	VERB
bjp-22865	140	64	100	100	NUM
bjp-22865	140	65	µm	µm	NOUN
bjp-22865	140	66	;	;	PUNCT
bjp-22865	140	67	l5	l5	PROPN
bjp-22865	140	68	-	-	PUNCT
bjp-22865	140	69	il-1	il-1	PUNCT
bjp-22865	140	70	+	+	X
bjp-22865	140	71	tangeretin	tangeretin	VERB
bjp-22865	140	72	50	50	NUM
bjp-22865	140	73	µm	µm	NOUN
bjp-22865	140	74	;	;	PUNCT
bjp-22865	140	75	l6	l6	NOUN
bjp-22865	140	76	-	-	PUNCT
bjp-22865	140	77	il-1	il-1	PUNCT
bjp-22865	140	78	+	+	X
bjp-22865	140	79	tangeretin	tangeretin	VERB
bjp-22865	140	80	100	100	NUM
bjp-22865	140	81	µm	µm	NUM
bjp-22865	140	82	;	;	PUNCT
bjp-22865	140	83	values	value	NOUN
bjp-22865	140	84	are	be	AUX
bjp-22865	140	85	represented	represent	VERB
bjp-22865	140	86	as	as	ADP
bjp-22865	140	87	mean	mean	NOUN
bjp-22865	140	88	±	±	NUM
bjp-22865	140	89	sd	sd	NOUN
bjp-22865	140	90	;	;	PUNCT
bjp-22865	140	91	n=3	n=3	NUM
bjp-22865	140	92	;	;	PUNCT
bjp-22865	140	93	*	*	PUNCT
bjp-22865	140	94	represents	represent	VERB
bjp-22865	140	95	statistical	statistical	ADJ
bjp-22865	140	96	significance	significance	NOUN
bjp-22865	140	97	at	at	ADP
bjp-22865	140	98	p<0.05	p<0.05	NOUN
bjp-22865	140	99	compared	compare	VERB
bjp-22865	140	100	against	against	ADP
bjp-22865	140	101	control	control	NOUN
bjp-22865	140	102	as	as	SCONJ
bjp-22865	140	103	determined	determine	VERB
bjp-22865	140	104	by	by	ADP
bjp-22865	140	105	one	one	NUM
bjp-22865	140	106	-	-	PUNCT
bjp-22865	140	107	way	way	NOUN
bjp-22865	140	108	anova	anova	PROPN
bjp-22865	140	109	g	g	PROPN
bjp-22865	140	110	h	h	PROPN
bjp-22865	140	111	bangladesh	bangladesh	PROPN
bjp-22865	140	112	j	j	PROPN
bjp-22865	140	113	pharmacol	pharmacol	PROPN
bjp-22865	140	114	2015	2015	NUM
bjp-22865	140	115	;	;	PUNCT
bjp-22865	140	116	10	10	NUM
bjp-22865	140	117	:	:	PUNCT
bjp-22865	140	118	714	714	NUM
bjp-22865	140	119	-	-	SYM
bjp-22865	140	120	725	725	NUM
bjp-22865	140	121	721	721	NUM
bjp-22865	140	122	figure	figure	NOUN
bjp-22865	140	123	5	5	NUM
bjp-22865	140	124	:	:	PUNCT
bjp-22865	140	125	tangeretin	tangeretin	VERB
bjp-22865	140	126	regulates	regulate	VERB
bjp-22865	140	127	the	the	DET
bjp-22865	140	128	expressions	expression	NOUN
bjp-22865	140	129	of	of	ADP
bjp-22865	140	130	nf	nf	NOUN
bjp-22865	140	131	-	-	PUNCT
bjp-22865	140	132	kb	kb	NOUN
bjp-22865	140	133	and	and	CCONJ
bjp-22865	140	134	ikb	ikb	VERB
bjp-22865	140	135	tangeretin	tangeretin	X
bjp-22865	140	136	significantly	significantly	ADV
bjp-22865	140	137	reduced	reduce	VERB
bjp-22865	140	138	the	the	DET
bjp-22865	140	139	nf	nf	ADJ
bjp-22865	140	140	-	-	PUNCT
bjp-22865	140	141	kb	kb	NOUN
bjp-22865	140	142	expression	expression	NOUN
bjp-22865	140	143	and	and	CCONJ
bjp-22865	140	144	regulated	regulate	VERB
bjp-22865	140	145	ikb	ikb	ADV
bjp-22865	140	146	;	;	PUNCT
bjp-22865	140	147	following	follow	VERB
bjp-22865	140	148	24	24	NUM
bjp-22865	140	149	hours	hour	NOUN
bjp-22865	140	150	(	(	PUNCT
bjp-22865	140	151	a	a	PRON
bjp-22865	140	152	and	and	CCONJ
bjp-22865	140	153	c	c	NOUN
bjp-22865	140	154	)	)	PUNCT
bjp-22865	140	155	and	and	CCONJ
bjp-22865	140	156	48	48	NUM
bjp-22865	140	157	h	h	NOUN
bjp-22865	140	158	(	(	PUNCT
bjp-22865	140	159	b	b	PROPN
bjp-22865	140	160	and	and	CCONJ
bjp-22865	140	161	d	d	NOUN
bjp-22865	140	162	)	)	PUNCT
bjp-22865	140	163	of	of	ADP
bjp-22865	140	164	exposure	exposure	NOUN
bjp-22865	140	165	;	;	PUNCT
bjp-22865	140	166	l1	l1	PROPN
bjp-22865	140	167	-	-	PUNCT
bjp-22865	140	168	control	control	NOUN
bjp-22865	140	169	;	;	PUNCT
bjp-22865	140	170	l2	l2	NOUN
bjp-22865	140	171	-	-	PUNCT
bjp-22865	140	172	il-1	il-1	PUNCT
bjp-22865	140	173	;	;	PUNCT
bjp-22865	140	174	l3	l3	NOUN
bjp-22865	140	175	-	-	PUNCT
bjp-22865	140	176	tangeretin	tangeretin	ADJ
bjp-22865	140	177	50	50	NUM
bjp-22865	140	178	µm	µm	NOUN
bjp-22865	140	179	;	;	PUNCT
bjp-22865	140	180	l4	l4	PROPN
bjp-22865	140	181	-	-	PUNCT
bjp-22865	140	182	tangeretin	tangeretin	NOUN
bjp-22865	140	183	100	100	NUM
bjp-22865	140	184	µm	µm	NOUN
bjp-22865	140	185	;	;	PUNCT
bjp-22865	140	186	l5	l5	PROPN
bjp-22865	140	187	-	-	PUNCT
bjp-22865	140	188	il-1	il-1	PUNCT
bjp-22865	140	189	+	+	X
bjp-22865	140	190	tangeretin	tangeretin	VERB
bjp-22865	140	191	50	50	NUM
bjp-22865	140	192	µm	µm	NOUN
bjp-22865	140	193	;	;	PUNCT
bjp-22865	140	194	l6	l6	NOUN
bjp-22865	140	195	-	-	PUNCT
bjp-22865	140	196	il-1	il-1	PUNCT
bjp-22865	140	197	+	+	X
bjp-22865	140	198	tangeretin	tangeretin	VERB
bjp-22865	140	199	100	100	NUM
bjp-22865	140	200	µm	µm	NUM
bjp-22865	140	201	;	;	PUNCT
bjp-22865	140	202	values	value	NOUN
bjp-22865	140	203	are	be	AUX
bjp-22865	140	204	represented	represent	VERB
bjp-22865	140	205	as	as	ADP
bjp-22865	140	206	mean	mean	NOUN
bjp-22865	140	207	±	±	NUM
bjp-22865	140	208	sd	sd	NOUN
bjp-22865	140	209	;	;	PUNCT
bjp-22865	140	210	n=3	n=3	NUM
bjp-22865	140	211	;	;	PUNCT
bjp-22865	140	212	*	*	PUNCT
bjp-22865	140	213	represents	represent	VERB
bjp-22865	140	214	statistical	statistical	ADJ
bjp-22865	140	215	significance	significance	NOUN
bjp-22865	140	216	at	at	ADP
bjp-22865	140	217	p<0.05	p<0.05	NOUN
bjp-22865	140	218	compared	compare	VERB
bjp-22865	140	219	against	against	ADP
bjp-22865	140	220	control	control	NOUN
bjp-22865	140	221	as	as	SCONJ
bjp-22865	140	222	determined	determine	VERB
bjp-22865	140	223	by	by	ADP
bjp-22865	140	224	one	one	NUM
bjp-22865	140	225	-	-	PUNCT
bjp-22865	140	226	way	way	NOUN
bjp-22865	140	227	anova	anova	PROPN
bjp-22865	141	1	a	a	DET
bjp-22865	141	2	b	b	PROPN
bjp-22865	141	3	c	c	NOUN
bjp-22865	141	4	d	d	SYM
bjp-22865	141	5	722	722	NUM
bjp-22865	141	6	bangladesh	bangladesh	NOUN
bjp-22865	141	7	j	j	PROPN
bjp-22865	141	8	pharmacol	pharmacol	PROPN
bjp-22865	141	9	2015	2015	NUM
bjp-22865	141	10	;	;	PUNCT
bjp-22865	141	11	10	10	NUM
bjp-22865	141	12	:	:	PUNCT
bjp-22865	141	13	714	714	NUM
bjp-22865	141	14	-	-	SYM
bjp-22865	141	15	725	725	NUM
bjp-22865	141	16	extracellular	extracellular	ADJ
bjp-22865	141	17	matrix	matrix	NOUN
bjp-22865	141	18	in	in	ADP
bjp-22865	141	19	articular	articular	ADJ
bjp-22865	141	20	structures	structure	NOUN
bjp-22865	141	21	.	.	PUNCT
bjp-22865	142	1	the	the	DET
bjp-22865	142	2	cartilage	cartilage	NOUN
bjp-22865	142	3	destruction	destruction	NOUN
bjp-22865	142	4	in	in	ADP
bjp-22865	142	5	ra	ra	PROPN
bjp-22865	142	6	is	be	AUX
bjp-22865	142	7	mainly	mainly	ADV
bjp-22865	142	8	caused	cause	VERB
bjp-22865	142	9	by	by	ADP
bjp-22865	142	10	the	the	DET
bjp-22865	142	11	activation	activation	NOUN
bjp-22865	142	12	of	of	ADP
bjp-22865	142	13	mmps	mmp	NOUN
bjp-22865	142	14	(	(	PUNCT
bjp-22865	142	15	feldmann	feldmann	PROPN
bjp-22865	142	16	et	et	NOUN
bjp-22865	142	17	al	al	PROPN
bjp-22865	142	18	.	.	PROPN
bjp-22865	142	19	,	,	PUNCT
bjp-22865	142	20	1996	1996	NUM
bjp-22865	142	21	)	)	PUNCT
bjp-22865	142	22	.	.	PUNCT
bjp-22865	143	1	mmp-1	mmp-1	PUNCT
bjp-22865	143	2	and	and	CCONJ
bjp-22865	143	3	-3	-3	VERB
bjp-22865	143	4	have	have	AUX
bjp-22865	143	5	been	be	AUX
bjp-22865	143	6	shown	show	VERB
bjp-22865	143	7	to	to	PART
bjp-22865	143	8	be	be	AUX
bjp-22865	143	9	the	the	DET
bjp-22865	143	10	major	major	ADJ
bjp-22865	143	11	enzymes	enzyme	NOUN
bjp-22865	143	12	produced	produce	VERB
bjp-22865	143	13	by	by	ADP
bjp-22865	143	14	the	the	DET
bjp-22865	143	15	synovial	synovial	ADJ
bjp-22865	143	16	fibroblasts	fibroblast	NOUN
bjp-22865	143	17	(	(	PUNCT
bjp-22865	143	18	konttinen	konttinen	NOUN
bjp-22865	143	19	et	et	PROPN
bjp-22865	143	20	al	al	PROPN
bjp-22865	143	21	.	.	PROPN
bjp-22865	143	22	,	,	PUNCT
bjp-22865	143	23	1999	1999	NUM
bjp-22865	143	24	)	)	PUNCT
bjp-22865	143	25	.	.	PUNCT
bjp-22865	144	1	mmp-1	mmp-1	VERB
bjp-22865	144	2	preferentially	preferentially	ADV
bjp-22865	144	3	degrades	degrade	VERB
bjp-22865	144	4	fibrillar	fibrillar	ADJ
bjp-22865	144	5	collagens	collagen	NOUN
bjp-22865	144	6	,	,	PUNCT
bjp-22865	144	7	whereas	whereas	SCONJ
bjp-22865	144	8	mmp-3	mmp-3	PRON
bjp-22865	144	9	degrades	degrade	VERB
bjp-22865	144	10	a	a	DET
bjp-22865	144	11	broad	broad	ADJ
bjp-22865	144	12	array	array	NOUN
bjp-22865	144	13	of	of	ADP
bjp-22865	144	14	extracellular	extracellular	ADJ
bjp-22865	144	15	matrix	matrix	NOUN
bjp-22865	144	16	substrates	substrate	NOUN
bjp-22865	144	17	(	(	PUNCT
bjp-22865	144	18	ogata	ogata	NOUN
bjp-22865	144	19	et	et	NOUN
bjp-22865	144	20	al	al	PROPN
bjp-22865	144	21	.	.	PROPN
bjp-22865	144	22	,	,	PUNCT
bjp-22865	144	23	1992	1992	NUM
bjp-22865	144	24	;	;	PUNCT
bjp-22865	144	25	knauper	knauper	NOUN
bjp-22865	144	26	et	et	PROPN
bjp-22865	144	27	al	al	PROPN
bjp-22865	144	28	.	.	PROPN
bjp-22865	144	29	,	,	PUNCT
bjp-22865	144	30	1996	1996	NUM
bjp-22865	144	31	;	;	PUNCT
bjp-22865	144	32	jackson	jackson	PROPN
bjp-22865	144	33	et	et	PROPN
bjp-22865	144	34	al	al	PROPN
bjp-22865	144	35	.	.	PROPN
bjp-22865	144	36	,	,	PUNCT
bjp-22865	144	37	2001	2001	NUM
bjp-22865	144	38	)	)	PUNCT
bjp-22865	144	39	.	.	PUNCT
bjp-22865	145	1	cox-2	cox-2	NUM
bjp-22865	145	2	is	be	AUX
bjp-22865	145	3	involved	involve	VERB
bjp-22865	145	4	in	in	ADP
bjp-22865	145	5	the	the	DET
bjp-22865	145	6	synthesis	synthesis	NOUN
bjp-22865	145	7	of	of	ADP
bjp-22865	145	8	inflammatory	inflammatory	ADJ
bjp-22865	145	9	mediators	mediator	NOUN
bjp-22865	145	10	and	and	CCONJ
bjp-22865	145	11	is	be	AUX
bjp-22865	145	12	responsible	responsible	ADJ
bjp-22865	145	13	for	for	ADP
bjp-22865	145	14	the	the	DET
bjp-22865	145	15	conversion	conversion	NOUN
bjp-22865	145	16	of	of	ADP
bjp-22865	145	17	the	the	DET
bjp-22865	145	18	free	free	ADJ
bjp-22865	145	19	arachidonic	arachidonic	ADJ
bjp-22865	145	20	acid	acid	NOUN
bjp-22865	145	21	to	to	ADP
bjp-22865	145	22	prostaglandins	prostaglandin	NOUN
bjp-22865	145	23	and	and	CCONJ
bjp-22865	145	24	variety	variety	NOUN
bjp-22865	145	25	of	of	ADP
bjp-22865	145	26	bioactive	bioactive	ADJ
bjp-22865	145	27	products	product	NOUN
bjp-22865	145	28	.	.	PUNCT
bjp-22865	146	1	pge2	pge2	PROPN
bjp-22865	146	2	,	,	PUNCT
bjp-22865	146	3	a	a	DET
bjp-22865	146	4	pleiotropic	pleiotropic	ADJ
bjp-22865	146	5	mediator	mediator	NOUN
bjp-22865	146	6	of	of	ADP
bjp-22865	146	7	inflammation	inflammation	NOUN
bjp-22865	146	8	,	,	PUNCT
bjp-22865	146	9	is	be	AUX
bjp-22865	146	10	involved	involve	VERB
bjp-22865	146	11	in	in	ADP
bjp-22865	146	12	various	various	ADJ
bjp-22865	146	13	pathological	pathological	ADJ
bjp-22865	146	14	processes	process	NOUN
bjp-22865	146	15	and	and	CCONJ
bjp-22865	146	16	further	far	ADV
bjp-22865	146	17	when	when	SCONJ
bjp-22865	146	18	in	in	ADP
bjp-22865	146	19	excess	excess	NOUN
bjp-22865	146	20	,	,	PUNCT
bjp-22865	146	21	it	it	PRON
bjp-22865	146	22	also	also	ADV
bjp-22865	146	23	elicits	elicit	VERB
bjp-22865	146	24	the	the	DET
bjp-22865	146	25	signs	sign	NOUN
bjp-22865	146	26	and	and	CCONJ
bjp-22865	146	27	symptoms	symptom	NOUN
bjp-22865	146	28	of	of	ADP
bjp-22865	146	29	inflammation	inflammation	NOUN
bjp-22865	146	30	(	(	PUNCT
bjp-22865	146	31	martel	martel	NOUN
bjp-22865	146	32	-	-	PUNCT
bjp-22865	146	33	pelletier	pelletier	PROPN
bjp-22865	146	34	et	et	PROPN
bjp-22865	146	35	al	al	PROPN
bjp-22865	146	36	.	.	PROPN
bjp-22865	146	37	,	,	PUNCT
bjp-22865	146	38	2004	2004	NUM
bjp-22865	146	39	)	)	PUNCT
bjp-22865	146	40	.	.	PUNCT
bjp-22865	147	1	in	in	ADP
bjp-22865	147	2	this	this	DET
bjp-22865	147	3	study	study	NOUN
bjp-22865	147	4	we	we	PRON
bjp-22865	147	5	observed	observe	VERB
bjp-22865	147	6	that	that	SCONJ
bjp-22865	147	7	tangeretin	tangeretin	VERB
bjp-22865	147	8	at	at	ADP
bjp-22865	147	9	both	both	CCONJ
bjp-22865	147	10	the	the	DET
bjp-22865	147	11	doses	dose	NOUN
bjp-22865	147	12	were	be	AUX
bjp-22865	147	13	able	able	ADJ
bjp-22865	147	14	to	to	PART
bjp-22865	147	15	down	down	VERB
bjp-22865	147	16	-	-	PUNCT
bjp-22865	147	17	regulate	regulate	VERB
bjp-22865	147	18	the	the	DET
bjp-22865	147	19	il-1	il-1	ADV
bjp-22865	147	20	-induced	-induce	VERB
bjp-22865	147	21	expressions	expression	NOUN
bjp-22865	147	22	of	of	ADP
bjp-22865	147	23	mmp-1,3	mmp-1,3	NOUN
bjp-22865	147	24	and	and	CCONJ
bjp-22865	147	25	cox-2	cox-2	ADV
bjp-22865	147	26	both	both	PRON
bjp-22865	147	27	at	at	ADP
bjp-22865	147	28	the	the	DET
bjp-22865	147	29	mrna	mrna	NOUN
bjp-22865	147	30	and	and	CCONJ
bjp-22865	147	31	protein	protein	NOUN
bjp-22865	147	32	levels	level	NOUN
bjp-22865	147	33	.	.	PUNCT
bjp-22865	148	1	down	down	ADP
bjp-22865	148	2	-	-	PUNCT
bjp-22865	148	3	regulation	regulation	NOUN
bjp-22865	148	4	of	of	ADP
bjp-22865	148	5	cox-2	cox-2	ADV
bjp-22865	148	6	observed	observe	VERB
bjp-22865	148	7	in	in	ADP
bjp-22865	148	8	tangeretin	tangeretin	NOUN
bjp-22865	148	9	treatment	treatment	NOUN
bjp-22865	148	10	also	also	ADV
bjp-22865	148	11	reflected	reflect	VERB
bjp-22865	148	12	in	in	ADP
bjp-22865	148	13	the	the	DET
bjp-22865	148	14	levels	level	NOUN
bjp-22865	148	15	of	of	ADP
bjp-22865	148	16	pge2	pge2	PROPN
bjp-22865	148	17	.	.	PUNCT
bjp-22865	149	1	we	we	PRON
bjp-22865	149	2	found	find	VERB
bjp-22865	149	3	that	that	DET
bjp-22865	149	4	tangeretin	tangeretin	NOUN
bjp-22865	149	5	caused	cause	VERB
bjp-22865	149	6	marked	mark	VERB
bjp-22865	149	7	decreases	decrease	NOUN
bjp-22865	149	8	in	in	ADP
bjp-22865	149	9	the	the	DET
bjp-22865	149	10	levels	level	NOUN
bjp-22865	149	11	of	of	ADP
bjp-22865	149	12	pge2	pge2	NOUN
bjp-22865	149	13	in	in	ADP
bjp-22865	149	14	a	a	DET
bjp-22865	149	15	dose	dose	NOUN
bjp-22865	149	16	-	-	PUNCT
bjp-22865	149	17	dependent	dependent	ADJ
bjp-22865	149	18	manner	manner	NOUN
bjp-22865	149	19	.	.	PUNCT
bjp-22865	150	1	the	the	DET
bjp-22865	150	2	pro	pro	ADJ
bjp-22865	150	3	-	-	ADJ
bjp-22865	150	4	inflammatory	inflammatory	ADJ
bjp-22865	150	5	cytokines	cytokine	NOUN
bjp-22865	150	6	,	,	PUNCT
bjp-22865	150	7	upon	upon	SCONJ
bjp-22865	150	8	binding	bind	VERB
bjp-22865	150	9	to	to	ADP
bjp-22865	150	10	the	the	DET
bjp-22865	150	11	respective	respective	ADJ
bjp-22865	150	12	receptors	receptor	NOUN
bjp-22865	150	13	initiate	initiate	VERB
bjp-22865	150	14	various	various	ADJ
bjp-22865	150	15	signalling	signal	VERB
bjp-22865	150	16	pathways	pathway	NOUN
bjp-22865	150	17	.	.	PUNCT
bjp-22865	151	1	cytokines	cytokine	NOUN
bjp-22865	151	2	,	,	PUNCT
bjp-22865	151	3	il-1	il-1	ADP
bjp-22865	151	4	induce	induce	VERB
bjp-22865	151	5	the	the	DET
bjp-22865	151	6	activation	activation	NOUN
bjp-22865	151	7	of	of	ADP
bjp-22865	151	8	nf	nf	NOUN
bjp-22865	151	9	-	-	PUNCT
bjp-22865	151	10	kb	kb	NOUN
bjp-22865	151	11	in	in	ADP
bjp-22865	151	12	ra	ra	PROPN
bjp-22865	151	13	(	(	PUNCT
bjp-22865	151	14	morel	morel	NOUN
bjp-22865	151	15	and	and	CCONJ
bjp-22865	151	16	berenbaum	berenbaum	NOUN
bjp-22865	151	17	,	,	PUNCT
bjp-22865	151	18	2004	2004	NUM
bjp-22865	151	19	;	;	PUNCT
bjp-22865	151	20	rannou	rannou	NOUN
bjp-22865	151	21	et	et	PROPN
bjp-22865	151	22	al	al	PROPN
bjp-22865	151	23	.	.	PROPN
bjp-22865	151	24	,	,	PUNCT
bjp-22865	151	25	2006	2006	NUM
bjp-22865	151	26	;	;	PUNCT
bjp-22865	151	27	lie	lie	VERB
bjp-22865	151	28	et	et	PROPN
bjp-22865	151	29	al	al	PROPN
bjp-22865	151	30	.	.	PROPN
bjp-22865	151	31	,	,	PUNCT
bjp-22865	151	32	2012	2012	NUM
bjp-22865	151	33	)	)	PUNCT
bjp-22865	151	34	.	.	PUNCT
bjp-22865	152	1	nf	nf	X
bjp-22865	152	2	-	-	PUNCT
bjp-22865	152	3	κb	κb	PROPN
bjp-22865	152	4	is	be	AUX
bjp-22865	152	5	an	an	DET
bjp-22865	152	6	important	important	ADJ
bjp-22865	152	7	transcriptional	transcriptional	ADJ
bjp-22865	152	8	factor	factor	NOUN
bjp-22865	152	9	complex	complex	NOUN
bjp-22865	152	10	that	that	PRON
bjp-22865	152	11	regulates	regulate	VERB
bjp-22865	152	12	the	the	DET
bjp-22865	152	13	expression	expression	NOUN
bjp-22865	152	14	of	of	ADP
bjp-22865	152	15	various	various	ADJ
bjp-22865	152	16	genes	gene	NOUN
bjp-22865	152	17	involved	involve	VERB
bjp-22865	152	18	in	in	ADP
bjp-22865	152	19	the	the	DET
bjp-22865	152	20	process	process	NOUN
bjp-22865	152	21	of	of	ADP
bjp-22865	152	22	inflammatory	inflammatory	ADJ
bjp-22865	152	23	response	response	NOUN
bjp-22865	152	24	(	(	PUNCT
bjp-22865	152	25	karin	karin	PROPN
bjp-22865	152	26	and	and	CCONJ
bjp-22865	152	27	lin	lin	PROPN
bjp-22865	152	28	,	,	PUNCT
bjp-22865	152	29	2002	2002	NUM
bjp-22865	152	30	;	;	PUNCT
bjp-22865	152	31	shaulian	shaulian	PROPN
bjp-22865	152	32	and	and	CCONJ
bjp-22865	152	33	karin	karin	PROPN
bjp-22865	152	34	,	,	PUNCT
bjp-22865	152	35	2002	2002	NUM
bjp-22865	152	36	)	)	PUNCT
bjp-22865	152	37	.	.	PUNCT
bjp-22865	153	1	in	in	ADP
bjp-22865	153	2	the	the	DET
bjp-22865	153	3	cell	cell	NOUN
bjp-22865	153	4	under	under	ADP
bjp-22865	153	5	normal	normal	ADJ
bjp-22865	153	6	conditions	condition	NOUN
bjp-22865	153	7	,	,	PUNCT
bjp-22865	153	8	nf	nf	NOUN
bjp-22865	153	9	-	-	PUNCT
bjp-22865	153	10	kb	kb	PROPN
bjp-22865	153	11	is	be	AUX
bjp-22865	153	12	maintained	maintain	VERB
bjp-22865	153	13	in	in	ADP
bjp-22865	153	14	an	an	DET
bjp-22865	153	15	inactive	inactive	ADJ
bjp-22865	153	16	state	state	NOUN
bjp-22865	153	17	within	within	ADP
bjp-22865	153	18	the	the	DET
bjp-22865	153	19	cytoplasm	cytoplasm	NOUN
bjp-22865	153	20	sequestered	sequester	VERB
bjp-22865	153	21	by	by	ADP
bjp-22865	153	22	ikb	ikb	PROPN
bjp-22865	153	23	.	.	PUNCT
bjp-22865	154	1	upon	upon	SCONJ
bjp-22865	154	2	stimulation	stimulation	NOUN
bjp-22865	154	3	chemokines	chemokine	NOUN
bjp-22865	154	4	like	like	ADP
bjp-22865	154	5	il-1	il-1	ADP
bjp-22865	154	6	,	,	PUNCT
bjp-22865	154	7	the	the	DET
bjp-22865	154	8	ikb	ikb	PROPN
bjp-22865	154	9	kinase	kinase	PROPN
bjp-22865	154	10	complex	complex	NOUN
bjp-22865	154	11	gets	get	VERB
bjp-22865	154	12	activated	activate	VERB
bjp-22865	154	13	leading	lead	VERB
bjp-22865	154	14	to	to	ADP
bjp-22865	154	15	phosphorylation	phosphorylation	NOUN
bjp-22865	154	16	and	and	CCONJ
bjp-22865	154	17	degradation	degradation	NOUN
bjp-22865	154	18	of	of	ADP
bjp-22865	154	19	ikb	ikb	PROPN
bjp-22865	154	20	.	.	PUNCT
bjp-22865	155	1	this	this	PRON
bjp-22865	155	2	further	far	ADV
bjp-22865	155	3	causes	cause	VERB
bjp-22865	155	4	a	a	DET
bjp-22865	155	5	transitory	transitory	ADJ
bjp-22865	155	6	increase	increase	NOUN
bjp-22865	155	7	in	in	ADP
bjp-22865	155	8	unbound	unbound	NOUN
bjp-22865	155	9	nf	nf	PROPN
bjp-22865	155	10	-	-	PUNCT
bjp-22865	155	11	kb	kb	NOUN
bjp-22865	155	12	molecules	molecule	NOUN
bjp-22865	155	13	that	that	PRON
bjp-22865	155	14	get	get	AUX
bjp-22865	155	15	activated	activate	VERB
bjp-22865	155	16	and	and	CCONJ
bjp-22865	155	17	translocate	translocate	VERB
bjp-22865	155	18	to	to	ADP
bjp-22865	155	19	the	the	DET
bjp-22865	155	20	nucleus	nucleus	NOUN
bjp-22865	155	21	,	,	PUNCT
bjp-22865	155	22	resulting	result	VERB
bjp-22865	155	23	in	in	ADP
bjp-22865	155	24	transcription	transcription	NOUN
bjp-22865	155	25	of	of	ADP
bjp-22865	155	26	inflammatory	inflammatory	ADJ
bjp-22865	155	27	responsive	responsive	ADJ
bjp-22865	155	28	genes	gene	NOUN
bjp-22865	155	29	(	(	PUNCT
bjp-22865	155	30	tak	tak	NOUN
bjp-22865	155	31	and	and	CCONJ
bjp-22865	155	32	firestein	firestein	ADJ
bjp-22865	155	33	,	,	PUNCT
bjp-22865	155	34	2001	2001	NUM
bjp-22865	155	35	;	;	PUNCT
bjp-22865	155	36	aggarwal	aggarwal	NOUN
bjp-22865	155	37	,	,	PUNCT
bjp-22865	155	38	2004	2004	NUM
bjp-22865	155	39	)	)	PUNCT
bjp-22865	155	40	.	.	PUNCT
bjp-22865	156	1	thus	thus	ADV
bjp-22865	156	2	,	,	PUNCT
bjp-22865	156	3	the	the	DET
bjp-22865	156	4	increase	increase	NOUN
bjp-22865	156	5	in	in	ADP
bjp-22865	156	6	nf	nf	ADJ
bjp-22865	156	7	-	-	PUNCT
bjp-22865	156	8	kb	kb	NOUN
bjp-22865	156	9	observed	observed	ADJ
bjp-22865	156	10	following	following	NOUN
bjp-22865	156	11	il-1	il-1	ADP
bjp-22865	156	12	treatment	treatment	NOUN
bjp-22865	156	13	in	in	ADP
bjp-22865	156	14	our	our	PRON
bjp-22865	156	15	study	study	NOUN
bjp-22865	156	16	is	be	AUX
bjp-22865	156	17	correlating	correlate	VERB
bjp-22865	156	18	with	with	ADP
bjp-22865	156	19	the	the	DET
bjp-22865	156	20	concurrent	concurrent	ADJ
bjp-22865	156	21	decrease	decrease	NOUN
bjp-22865	156	22	in	in	ADP
bjp-22865	156	23	expression	expression	NOUN
bjp-22865	156	24	of	of	ADP
bjp-22865	156	25	ikb	ikb	PROPN
bjp-22865	156	26	.	.	PUNCT
bjp-22865	157	1	tangeretin	tangeretin	PROPN
bjp-22865	157	2	was	be	AUX
bjp-22865	157	3	able	able	ADJ
bjp-22865	157	4	to	to	PART
bjp-22865	157	5	considerably	considerably	ADV
bjp-22865	157	6	regulate	regulate	VERB
bjp-22865	157	7	the	the	DET
bjp-22865	157	8	expressions	expression	NOUN
bjp-22865	157	9	of	of	ADP
bjp-22865	157	10	ikb	ikb	PROPN
bjp-22865	157	11	and	and	CCONJ
bjp-22865	157	12	nf	nf	NOUN
bjp-22865	157	13	-	-	PUNCT
bjp-22865	157	14	kb	kb	NOUN
bjp-22865	157	15	.	.	PUNCT
bjp-22865	158	1	at	at	ADP
bjp-22865	158	2	both	both	CCONJ
bjp-22865	158	3	the	the	DET
bjp-22865	158	4	doses	dose	NOUN
bjp-22865	158	5	(	(	PUNCT
bjp-22865	158	6	50	50	NUM
bjp-22865	158	7	and	and	CCONJ
bjp-22865	158	8	100	100	NUM
bjp-22865	158	9	µm	µm	NOUN
bjp-22865	158	10	)	)	PUNCT
bjp-22865	158	11	tangeretin	tangeretin	VERB
bjp-22865	158	12	significantly	significantly	ADV
bjp-22865	158	13	down	down	ADV
bjp-22865	158	14	-	-	PUNCT
bjp-22865	158	15	regulated	regulate	VERB
bjp-22865	158	16	nf	nf	NOUN
bjp-22865	158	17	-	-	PUNCT
bjp-22865	158	18	kb	kb	NOUN
bjp-22865	158	19	.	.	PUNCT
bjp-22865	159	1	the	the	DET
bjp-22865	159	2	results	result	NOUN
bjp-22865	159	3	suggest	suggest	VERB
bjp-22865	159	4	that	that	SCONJ
bjp-22865	159	5	tangeretin	tangeretin	NOUN
bjp-22865	159	6	was	be	AUX
bjp-22865	159	7	able	able	ADJ
bjp-22865	159	8	to	to	PART
bjp-22865	159	9	inhibit	inhibit	VERB
bjp-22865	159	10	il-1	il-1	ADP
bjp-22865	159	11	induced	induce	VERB
bjp-22865	159	12	inflammatory	inflammatory	ADJ
bjp-22865	159	13	responses	response	NOUN
bjp-22865	159	14	as	as	ADP
bjp-22865	159	15	evident	evident	ADJ
bjp-22865	159	16	from	from	ADP
bjp-22865	159	17	marked	mark	VERB
bjp-22865	159	18	decrease	decrease	NOUN
bjp-22865	159	19	in	in	ADP
bjp-22865	159	20	the	the	DET
bjp-22865	159	21	cell	cell	NOUN
bjp-22865	159	22	proliferation	proliferation	NOUN
bjp-22865	159	23	and	and	CCONJ
bjp-22865	159	24	production	production	NOUN
bjp-22865	159	25	of	of	ADP
bjp-22865	159	26	pge2	pge2	PROPN
bjp-22865	159	27	.	.	PUNCT
bjp-22865	160	1	mapks	mapks	NOUN
bjp-22865	160	2	are	be	AUX
bjp-22865	160	3	involved	involve	VERB
bjp-22865	160	4	in	in	ADP
bjp-22865	160	5	a	a	DET
bjp-22865	160	6	wide	wide	ADJ
bjp-22865	160	7	variety	variety	NOUN
bjp-22865	160	8	of	of	ADP
bjp-22865	160	9	cellular	cellular	ADJ
bjp-22865	160	10	processes	process	NOUN
bjp-22865	160	11	such	such	ADJ
bjp-22865	160	12	as	as	ADP
bjp-22865	160	13	inflammation	inflammation	NOUN
bjp-22865	160	14	(	(	PUNCT
bjp-22865	160	15	su	su	PROPN
bjp-22865	160	16	and	and	CCONJ
bjp-22865	160	17	karin	karin	PROPN
bjp-22865	160	18	,	,	PUNCT
bjp-22865	160	19	1996	1996	NUM
bjp-22865	160	20	;	;	PUNCT
bjp-22865	160	21	dong	dong	PROPN
bjp-22865	160	22	et	et	PROPN
bjp-22865	160	23	al	al	PROPN
bjp-22865	160	24	.	.	PROPN
bjp-22865	160	25	,	,	PUNCT
bjp-22865	160	26	2002	2002	NUM
bjp-22865	160	27	)	)	PUNCT
bjp-22865	160	28	.	.	PUNCT
bjp-22865	161	1	the	the	DET
bjp-22865	161	2	major	major	ADJ
bjp-22865	161	3	members	member	NOUN
bjp-22865	161	4	of	of	ADP
bjp-22865	161	5	mapk	mapk	PROPN
bjp-22865	161	6	families	families	PROPN
bjp-22865	161	7	erk	erk	PROPN
bjp-22865	161	8	,	,	PUNCT
bjp-22865	161	9	jnk	jnk	PROPN
bjp-22865	161	10	,	,	PUNCT
bjp-22865	161	11	and	and	CCONJ
bjp-22865	161	12	p38	p38	NOUN
bjp-22865	161	13	kinases	kinase	NOUN
bjp-22865	161	14	,	,	PUNCT
bjp-22865	161	15	are	be	AUX
bjp-22865	161	16	expressed	express	VERB
bjp-22865	161	17	in	in	ADP
bjp-22865	161	18	active	active	ADJ
bjp-22865	161	19	forms	form	NOUN
bjp-22865	161	20	in	in	ADP
bjp-22865	161	21	synovial	synovial	ADJ
bjp-22865	161	22	tissue	tissue	NOUN
bjp-22865	161	23	and	and	CCONJ
bjp-22865	161	24	in	in	ADP
bjp-22865	161	25	cultured	cultured	ADJ
bjp-22865	161	26	rasfs	rasfs	NOUN
bjp-22865	161	27	(	(	PUNCT
bjp-22865	161	28	schett	schett	PROPN
bjp-22865	161	29	et	et	PROPN
bjp-22865	161	30	al	al	PROPN
bjp-22865	161	31	.	.	PROPN
bjp-22865	161	32	,	,	PUNCT
bjp-22865	161	33	2000	2000	NUM
bjp-22865	161	34	;	;	PUNCT
bjp-22865	161	35	han	han	PROPN
bjp-22865	161	36	et	et	PROPN
bjp-22865	161	37	al	al	PROPN
bjp-22865	161	38	.	.	PROPN
bjp-22865	161	39	,	,	PUNCT
bjp-22865	161	40	2001	2001	NUM
bjp-22865	161	41	;	;	PUNCT
bjp-22865	161	42	sweeney	sweeney	NOUN
bjp-22865	161	43	and	and	CCONJ
bjp-22865	161	44	firestein	firestein	PROPN
bjp-22865	161	45	,	,	PUNCT
bjp-22865	161	46	2004	2004	NUM
bjp-22865	161	47	)	)	PUNCT
bjp-22865	161	48	.	.	PUNCT
bjp-22865	162	1	several	several	ADJ
bjp-22865	162	2	reports	report	NOUN
bjp-22865	162	3	have	have	AUX
bjp-22865	162	4	demonstrated	demonstrate	VERB
bjp-22865	162	5	that	that	SCONJ
bjp-22865	162	6	inhibitors	inhibitor	NOUN
bjp-22865	162	7	of	of	ADP
bjp-22865	162	8	nf‑κb	nf‑κb	NUM
bjp-22865	162	9	or	or	CCONJ
bjp-22865	162	10	mapks	mapks	NOUN
bjp-22865	162	11	reduce	reduce	VERB
bjp-22865	162	12	synovial	synovial	ADJ
bjp-22865	162	13	inflammation	inflammation	NOUN
bjp-22865	162	14	,	,	PUNCT
bjp-22865	162	15	bone	bone	NOUN
bjp-22865	162	16	destruction	destruction	NOUN
bjp-22865	162	17	and	and	CCONJ
bjp-22865	162	18	cartilage	cartilage	NOUN
bjp-22865	162	19	damage	damage	NOUN
bjp-22865	162	20	in	in	ADP
bjp-22865	162	21	animal	animal	NOUN
bjp-22865	162	22	models	model	NOUN
bjp-22865	162	23	of	of	ADP
bjp-22865	162	24	arthritis	arthritis	NOUN
bjp-22865	162	25	(	(	PUNCT
bjp-22865	162	26	mcintyre	mcintyre	PROPN
bjp-22865	162	27	et	et	PROPN
bjp-22865	162	28	al	al	PROPN
bjp-22865	162	29	.	.	PROPN
bjp-22865	162	30	,	,	PUNCT
bjp-22865	162	31	2003	2003	NUM
bjp-22865	162	32	;	;	PUNCT
bjp-22865	162	33	nishikawa	nishikawa	PROPN
bjp-22865	162	34	et	et	PROPN
bjp-22865	162	35	al	al	PROPN
bjp-22865	162	36	.	.	PROPN
bjp-22865	162	37	,	,	PUNCT
bjp-22865	162	38	2003	2003	NUM
bjp-22865	162	39	)	)	PUNCT
bjp-22865	162	40	.	.	PUNCT
bjp-22865	163	1	in	in	ADP
bjp-22865	163	2	our	our	PRON
bjp-22865	163	3	study	study	NOUN
bjp-22865	163	4	,	,	PUNCT
bjp-22865	163	5	increased	increase	VERB
bjp-22865	163	6	activated	activate	VERB
bjp-22865	163	7	forms	form	NOUN
bjp-22865	163	8	of	of	ADP
bjp-22865	163	9	mapk	mapk	NOUN
bjp-22865	163	10	kinases	kinase	NOUN
bjp-22865	163	11	(	(	PUNCT
bjp-22865	163	12	jnk	jnk	PROPN
bjp-22865	163	13	,	,	PUNCT
bjp-22865	163	14	erk	erk	PROPN
bjp-22865	163	15	,	,	PUNCT
bjp-22865	163	16	p38	p38	NOUN
bjp-22865	163	17	)	)	PUNCT
bjp-22865	163	18	were	be	AUX
bjp-22865	163	19	seen	see	VERB
bjp-22865	163	20	upon	upon	SCONJ
bjp-22865	163	21	il-1	il-1	ADP
bjp-22865	163	22	exposure	exposure	NOUN
bjp-22865	163	23	suggesting	suggest	VERB
bjp-22865	163	24	the	the	DET
bjp-22865	163	25	activation	activation	NOUN
bjp-22865	163	26	of	of	ADP
bjp-22865	163	27	the	the	DET
bjp-22865	163	28	signal	signal	ADJ
bjp-22865	163	29	transduction	transduction	NOUN
bjp-22865	163	30	pathways	pathway	NOUN
bjp-22865	163	31	.	.	PUNCT
bjp-22865	164	1	however	however	ADV
bjp-22865	164	2	,	,	PUNCT
bjp-22865	164	3	significant	significant	ADJ
bjp-22865	164	4	down	down	ADJ
bjp-22865	164	5	-	-	PUNCT
bjp-22865	164	6	regulation	regulation	NOUN
bjp-22865	164	7	in	in	ADP
bjp-22865	164	8	the	the	DET
bjp-22865	164	9	phosphorylated	phosphorylate	VERB
bjp-22865	164	10	forms	form	NOUN
bjp-22865	164	11	of	of	ADP
bjp-22865	164	12	erk	erk	PROPN
bjp-22865	164	13	,	,	PUNCT
bjp-22865	164	14	jnk	jnk	PROPN
bjp-22865	164	15	and	and	CCONJ
bjp-22865	164	16	p38	p38	NOUN
bjp-22865	164	17	kinases	kinase	NOUN
bjp-22865	164	18	were	be	AUX
bjp-22865	164	19	observed	observe	VERB
bjp-22865	164	20	following	follow	VERB
bjp-22865	164	21	tangeretin	tangeretin	NOUN
bjp-22865	164	22	exposure	exposure	NOUN
bjp-22865	164	23	,	,	PUNCT
bjp-22865	164	24	suggesting	suggest	VERB
bjp-22865	164	25	that	that	PRON
bjp-22865	164	26	tangeretin	tangeretin	NOUN
bjp-22865	164	27	was	be	AUX
bjp-22865	164	28	able	able	ADJ
bjp-22865	164	29	to	to	PART
bjp-22865	164	30	effectively	effectively	ADV
bjp-22865	164	31	regulate	regulate	VERB
bjp-22865	164	32	the	the	DET
bjp-22865	164	33	alterations	alteration	NOUN
bjp-22865	164	34	in	in	ADP
bjp-22865	164	35	the	the	DET
bjp-22865	164	36	mapk	mapk	NOUN
bjp-22865	164	37	signalling	signal	VERB
bjp-22865	164	38	cascades	cascade	NOUN
bjp-22865	164	39	in	in	ADP
bjp-22865	164	40	rasfs	rasfs	PROPN
bjp-22865	164	41	.	.	PUNCT
bjp-22865	165	1	conclusion	conclusion	NOUN
bjp-22865	165	2	tangeretin	tangeretin	NOUN
bjp-22865	165	3	was	be	AUX
bjp-22865	165	4	found	find	VERB
bjp-22865	165	5	effective	effective	ADJ
bjp-22865	165	6	in	in	ADP
bjp-22865	165	7	inhibiting	inhibit	VERB
bjp-22865	165	8	il-1	il-1	ADP
bjp-22865	165	9	induced	induce	VERB
bjp-22865	165	10	rasfs	rasfs	ADJ
bjp-22865	165	11	proliferation	proliferation	NOUN
bjp-22865	165	12	and	and	CCONJ
bjp-22865	165	13	also	also	ADV
bjp-22865	165	14	regulates	regulate	VERB
bjp-22865	165	15	the	the	DET
bjp-22865	165	16	inflammatory	inflammatory	ADJ
bjp-22865	165	17	responses	response	NOUN
bjp-22865	165	18	.	.	PUNCT
bjp-22865	166	1	it	it	PRON
bjp-22865	166	2	also	also	ADV
bjp-22865	166	3	reduced	reduce	VERB
bjp-22865	166	4	the	the	DET
bjp-22865	166	5	signalling	signal	VERB
bjp-22865	166	6	pathways	pathway	NOUN
bjp-22865	166	7	,	,	PUNCT
bjp-22865	166	8	blocked	block	VERB
bjp-22865	166	9	the	the	DET
bjp-22865	166	10	expressions	expression	NOUN
bjp-22865	166	11	of	of	ADP
bjp-22865	166	12	transcription	transcription	NOUN
bjp-22865	166	13	factors	factor	NOUN
bjp-22865	166	14	,	,	PUNCT
bjp-22865	166	15	reduced	reduce	VERB
bjp-22865	166	16	the	the	DET
bjp-22865	166	17	generation	generation	NOUN
bjp-22865	166	18	and	and	CCONJ
bjp-22865	166	19	effects	effect	NOUN
bjp-22865	166	20	of	of	ADP
bjp-22865	166	21	chemokines	chemokine	NOUN
bjp-22865	166	22	.	.	PUNCT
bjp-22865	167	1	references	reference	NOUN
bjp-22865	167	2	adcock	adcock	NOUN
bjp-22865	167	3	i	i	PRON
bjp-22865	167	4	m.	m.	NOUN
bjp-22865	167	5	transcription	transcription	NOUN
bjp-22865	167	6	factors	factor	NOUN
bjp-22865	167	7	as	as	ADP
bjp-22865	167	8	activators	activator	NOUN
bjp-22865	167	9	of	of	ADP
bjp-22865	167	10	gene	gene	NOUN
bjp-22865	167	11	transcription	transcription	NOUN
bjp-22865	167	12	:	:	PUNCT
bjp-22865	167	13	ap-1	ap-1	NOUN
bjp-22865	167	14	and	and	CCONJ
bjp-22865	167	15	nf	nf	PROPN
bjp-22865	167	16	-	-	PUNCT
bjp-22865	167	17	kappa	kappa	PROPN
bjp-22865	167	18	b.	b.	PROPN
bjp-22865	168	1	in	in	ADP
bjp-22865	168	2	:	:	PUNCT
bjp-22865	168	3	monaldi	monaldi	ADJ
bjp-22865	168	4	archives	archive	NOUN
bjp-22865	168	5	for	for	ADP
bjp-22865	168	6	chest	chest	NOUN
bjp-22865	168	7	disease	disease	NOUN
bjp-22865	168	8	(	(	PUNCT
bjp-22865	168	9	archivio	archivio	NOUN
bjp-22865	168	10	monaldi	monaldi	NOUN
bjp-22865	168	11	per	per	X
bjp-22865	168	12	le	le	X
bjp-22865	168	13	malattie	malattie	PROPN
bjp-22865	168	14	del	del	PROPN
bjp-22865	168	15	torace	torace	NOUN
bjp-22865	168	16	/	/	SYM
bjp-22865	168	17	fondazione	fondazione	PROPN
bjp-22865	168	18	clinica	clinica	PROPN
bjp-22865	168	19	del	del	PROPN
bjp-22865	168	20	lavoro	lavoro	PROPN
bjp-22865	168	21	)	)	PUNCT
bjp-22865	168	22	.	.	PUNCT
bjp-22865	169	1	vol	vol	NOUN
bjp-22865	169	2	.	.	PUNCT
bjp-22865	170	1	52	52	NUM
bjp-22865	170	2	.	.	PUNCT
bjp-22865	171	1	irccs	ircc	VERB
bjp-22865	172	1	[	[	X
bjp-22865	172	2	and	and	CCONJ
bjp-22865	172	3	]	]	X
bjp-22865	172	4	istituto	istituto	X
bjp-22865	172	5	di	di	X
bjp-22865	172	6	clinica	clinica	PROPN
bjp-22865	172	7	tisiologica	tisiologica	PROPN
bjp-22865	172	8	e	e	PROPN
bjp-22865	172	9	malattie	malattie	PROPN
bjp-22865	172	10	apparato	apparato	PROPN
bjp-22865	172	11	respiratorio	respiratorio	PROPN
bjp-22865	172	12	,	,	PUNCT
bjp-22865	172	13	universita	universita	PROPN
bjp-22865	172	14	di	di	PROPN
bjp-22865	172	15	napoli	napoli	PROPN
bjp-22865	172	16	,	,	PUNCT
bjp-22865	172	17	secondo	secondo	PROPN
bjp-22865	172	18	ateneo	ateneo	PROPN
bjp-22865	172	19	.	.	PUNCT
bjp-22865	173	1	1997	1997	NUM
bjp-22865	173	2	,	,	PUNCT
bjp-22865	173	3	pp	pp	ADP
bjp-22865	173	4	178	178	NUM
bjp-22865	173	5	-	-	SYM
bjp-22865	173	6	86	86	NUM
bjp-22865	173	7	.	.	PUNCT
bjp-22865	174	1	aggarwal	aggarwal	NOUN
bjp-22865	174	2	bb	bb	PROPN
bjp-22865	174	3	.	.	PUNCT
bjp-22865	174	4	nuclear	nuclear	ADJ
bjp-22865	174	5	factor	factor	NOUN
bjp-22865	174	6	-	-	PUNCT
bjp-22865	174	7	kappa	kappa	PROPN
bjp-22865	175	1	b	b	PROPN
bjp-22865	175	2	:	:	PUNCT
bjp-22865	175	3	the	the	DET
bjp-22865	175	4	enemy	enemy	NOUN
bjp-22865	175	5	within	within	ADP
bjp-22865	175	6	.	.	PUNCT
bjp-22865	176	1	cancer	cancer	NOUN
bjp-22865	176	2	cell	cell	NOUN
bjp-22865	176	3	.	.	PUNCT
bjp-22865	177	1	2004	2004	NUM
bjp-22865	177	2	;	;	PUNCT
bjp-22865	177	3	6	6	NUM
bjp-22865	177	4	:	:	SYM
bjp-22865	177	5	203	203	NUM
bjp-22865	177	6	-	-	SYM
bjp-22865	177	7	08	08	NUM
bjp-22865	177	8	.	.	PUNCT
bjp-22865	178	1	arend	arend	VERB
bjp-22865	178	2	wp	wp	PROPN
bjp-22865	178	3	.	.	PUNCT
bjp-22865	179	1	cytokines	cytokine	NOUN
bjp-22865	179	2	and	and	CCONJ
bjp-22865	179	3	cellular	cellular	ADJ
bjp-22865	179	4	interactions	interaction	NOUN
bjp-22865	179	5	in	in	ADP
bjp-22865	179	6	inflammatory	inflammatory	ADJ
bjp-22865	179	7	synovitis	synovitis	NOUN
bjp-22865	179	8	.	.	PUNCT
bjp-22865	180	1	j	j	PROPN
bjp-22865	180	2	clin	clin	PROPN
bjp-22865	180	3	invest	invest	PROPN
bjp-22865	180	4	.	.	PUNCT
bjp-22865	181	1	2001	2001	NUM
bjp-22865	181	2	;	;	PUNCT
bjp-22865	181	3	107	107	NUM
bjp-22865	181	4	:	:	PUNCT
bjp-22865	181	5	1081	1081	NUM
bjp-22865	181	6	-	-	SYM
bjp-22865	181	7	82	82	NUM
bjp-22865	181	8	.	.	PUNCT
bjp-22865	182	1	arnett	arnett	PROPN
bjp-22865	182	2	fc	fc	PROPN
bjp-22865	182	3	,	,	PUNCT
bjp-22865	182	4	edworthy	edworthy	PROPN
bjp-22865	182	5	sm	sm	PROPN
bjp-22865	182	6	,	,	PUNCT
bjp-22865	182	7	bloch	bloch	PROPN
bjp-22865	182	8	da	da	PROPN
bjp-22865	182	9	,	,	PUNCT
bjp-22865	182	10	mcshane	mcshane	PROPN
bjp-22865	182	11	dj	dj	PROPN
bjp-22865	182	12	,	,	PUNCT
bjp-22865	182	13	fries	fries	PROPN
bjp-22865	182	14	jf	jf	PROPN
bjp-22865	182	15	,	,	PUNCT
bjp-22865	182	16	cooper	cooper	PROPN
bjp-22865	182	17	ns	ns	PROPN
bjp-22865	182	18	,	,	PUNCT
bjp-22865	182	19	healey	healey	PROPN
bjp-22865	182	20	la	la	PROPN
bjp-22865	182	21	,	,	PUNCT
bjp-22865	182	22	kaplan	kaplan	PROPN
bjp-22865	182	23	sr	sr	PROPN
bjp-22865	182	24	,	,	PUNCT
bjp-22865	182	25	liang	liang	PROPN
bjp-22865	182	26	mh	mh	PROPN
bjp-22865	182	27	,	,	PUNCT
bjp-22865	182	28	luthra	luthra	PROPN
bjp-22865	182	29	hs	hs	PROPN
bjp-22865	182	30	.	.	PUNCT
bjp-22865	183	1	the	the	DET
bjp-22865	183	2	american	american	ADJ
bjp-22865	183	3	rheumatism	rheumatism	PROPN
bjp-22865	183	4	association	association	PROPN
bjp-22865	183	5	1987	1987	NUM
bjp-22865	183	6	revised	revise	VERB
bjp-22865	183	7	criteria	criterion	NOUN
bjp-22865	183	8	for	for	ADP
bjp-22865	183	9	the	the	DET
bjp-22865	183	10	classification	classification	NOUN
bjp-22865	183	11	of	of	ADP
bjp-22865	183	12	rheumatoid	rheumatoid	NOUN
bjp-22865	183	13	arthritis	arthritis	NOUN
bjp-22865	183	14	.	.	PUNCT
bjp-22865	184	1	arthritis	arthritis	NOUN
bjp-22865	184	2	rheum	rheum	NOUN
bjp-22865	184	3	.	.	PUNCT
bjp-22865	185	1	1998	1998	NUM
bjp-22865	185	2	;	;	PUNCT
bjp-22865	185	3	31	31	NUM
bjp-22865	185	4	:	:	SYM
bjp-22865	185	5	315	315	NUM
bjp-22865	185	6	-	-	SYM
bjp-22865	185	7	24	24	NUM
bjp-22865	185	8	.	.	PUNCT
bjp-22865	186	1	cawston	cawston	PROPN
bjp-22865	186	2	te	te	PROPN
bjp-22865	186	3	.	.	PUNCT
bjp-22865	186	4	proteinase	proteinase	PROPN
bjp-22865	186	5	and	and	CCONJ
bjp-22865	186	6	connective	connective	ADJ
bjp-22865	186	7	tissue	tissue	NOUN
bjp-22865	186	8	breakdown	breakdown	NOUN
bjp-22865	186	9	.	.	PUNCT
bjp-22865	187	1	in	in	ADP
bjp-22865	187	2	:	:	PUNCT
bjp-22865	187	3	mechanisms	mechanism	NOUN
bjp-22865	187	4	and	and	CCONJ
bjp-22865	187	5	models	model	NOUN
bjp-22865	187	6	in	in	ADP
bjp-22865	187	7	rheumatoid	rheumatoid	NOUN
bjp-22865	187	8	arthritis	arthritis	NOUN
bjp-22865	187	9	.	.	PUNCT
bjp-22865	188	1	henderson	henderson	PROPN
bjp-22865	188	2	b	b	PROPN
bjp-22865	188	3	,	,	PUNCT
bjp-22865	188	4	edwards	edwards	PROPN
bjp-22865	188	5	jcw	jcw	PROPN
bjp-22865	188	6	,	,	PUNCT
bjp-22865	188	7	pettipher	pettipher	X
bjp-22865	188	8	er	er	INTJ
bjp-22865	188	9	(	(	PUNCT
bjp-22865	188	10	eds	ed	NOUN
bjp-22865	188	11	)	)	PUNCT
bjp-22865	188	12	.	.	PUNCT
bjp-22865	189	1	london	london	PROPN
bjp-22865	189	2	,	,	PUNCT
bjp-22865	189	3	academic	academic	ADJ
bjp-22865	189	4	press	press	NOUN
bjp-22865	189	5	,	,	PUNCT
bjp-22865	189	6	1995	1995	NUM
bjp-22865	189	7	.	.	PUNCT
bjp-22865	190	1	chen	chen	PROPN
bjp-22865	190	2	zt	zt	PROPN
bjp-22865	190	3	,	,	PUNCT
bjp-22865	190	4	chu	chu	PROPN
bjp-22865	190	5	hl	hl	PROPN
bjp-22865	190	6	,	,	PUNCT
bjp-22865	190	7	chyau	chyau	PROPN
bjp-22865	190	8	cc	cc	PROPN
bjp-22865	190	9	,	,	PUNCT
bjp-22865	190	10	chu	chu	PROPN
bjp-22865	190	11	cc	cc	PROPN
bjp-22865	190	12	,	,	PUNCT
bjp-22865	190	13	duh	duh	INTJ
bjp-22865	190	14	pd	pd	PROPN
bjp-22865	190	15	.	.	PUNCT
bjp-22865	190	16	protective	protective	ADJ
bjp-22865	190	17	effects	effect	NOUN
bjp-22865	190	18	of	of	ADP
bjp-22865	190	19	sweet	sweet	ADJ
bjp-22865	190	20	orange	orange	NOUN
bjp-22865	190	21	(	(	PUNCT
bjp-22865	190	22	citrus	citrus	NOUN
bjp-22865	190	23	sinensis	sinensis	NOUN
bjp-22865	190	24	)	)	PUNCT
bjp-22865	190	25	peel	peel	NOUN
bjp-22865	190	26	and	and	CCONJ
bjp-22865	190	27	their	their	PRON
bjp-22865	190	28	bioactive	bioactive	ADJ
bjp-22865	190	29	compounds	compound	NOUN
bjp-22865	190	30	on	on	ADP
bjp-22865	190	31	oxidative	oxidative	ADJ
bjp-22865	190	32	stress	stress	NOUN
bjp-22865	190	33	.	.	PUNCT
bjp-22865	191	1	food	food	NOUN
bjp-22865	191	2	chem	chem	NOUN
bjp-22865	191	3	.	.	PUNCT
bjp-22865	192	1	2012	2012	NUM
bjp-22865	192	2	;	;	PUNCT
bjp-22865	192	3	135	135	NUM
bjp-22865	192	4	:	:	SYM
bjp-22865	192	5	2119	2119	NUM
bjp-22865	192	6	-	-	SYM
bjp-22865	192	7	27	27	NUM
bjp-22865	192	8	.	.	PUNCT
bjp-22865	193	1	choy	choy	NOUN
bjp-22865	193	2	eh	eh	INTJ
bjp-22865	193	3	,	,	PUNCT
bjp-22865	193	4	panayi	panayi	NOUN
bjp-22865	193	5	gs	gs	AUX
bjp-22865	193	6	.	.	PUNCT
bjp-22865	193	7	cytokine	cytokine	VERB
bjp-22865	193	8	pathways	pathway	NOUN
bjp-22865	193	9	and	and	CCONJ
bjp-22865	193	10	joint	joint	ADJ
bjp-22865	193	11	inflammation	inflammation	NOUN
bjp-22865	193	12	in	in	ADP
bjp-22865	193	13	rheumatoid	rheumatoid	NOUN
bjp-22865	193	14	arthritis	arthritis	NOUN
bjp-22865	193	15	.	.	PUNCT
bjp-22865	194	1	n	n	PROPN
bjp-22865	194	2	engl	engl	PROPN
bjp-22865	194	3	j	j	PROPN
bjp-22865	194	4	med	med	PROPN
bjp-22865	194	5	.	.	PUNCT
bjp-22865	194	6	2001	2001	NUM
bjp-22865	194	7	;	;	PUNCT
bjp-22865	194	8	344	344	NUM
bjp-22865	194	9	:	:	PUNCT
bjp-22865	194	10	907	907	NUM
bjp-22865	194	11	-	-	SYM
bjp-22865	194	12	16	16	NUM
bjp-22865	194	13	.	.	PUNCT
bjp-22865	195	1	choy	choy	NOUN
bjp-22865	195	2	e.	e.	PROPN
bjp-22865	195	3	understanding	understand	VERB
bjp-22865	195	4	the	the	DET
bjp-22865	195	5	dynamics	dynamic	NOUN
bjp-22865	195	6	:	:	PUNCT
bjp-22865	195	7	pathways	pathway	NOUN
bjp-22865	195	8	involved	involve	VERB
bjp-22865	195	9	in	in	ADP
bjp-22865	195	10	the	the	DET
bjp-22865	195	11	pathogenesis	pathogenesis	NOUN
bjp-22865	195	12	of	of	ADP
bjp-22865	195	13	rheumatoid	rheumatoid	NOUN
bjp-22865	195	14	arthritis	arthritis	NOUN
bjp-22865	195	15	.	.	PUNCT
bjp-22865	196	1	rheumatology	rheumatology	NOUN
bjp-22865	196	2	2012	2012	NUM
bjp-22865	196	3	;	;	PUNCT
bjp-22865	196	4	51	51	NUM
bjp-22865	196	5	:	:	PUNCT
bjp-22865	196	6	v3	v3	PROPN
bjp-22865	196	7	-	-	PUNCT
bjp-22865	196	8	11	11	NUM
bjp-22865	196	9	.	.	PUNCT
bjp-22865	197	1	crofford	crofford	PROPN
bjp-22865	197	2	lj	lj	PROPN
bjp-22865	197	3	,	,	PUNCT
bjp-22865	197	4	wilder	wilder	ADJ
bjp-22865	197	5	rl	rl	PROPN
bjp-22865	197	6	,	,	PUNCT
bjp-22865	197	7	ristimaki	ristimaki	PROPN
bjp-22865	197	8	ap	ap	PROPN
bjp-22865	197	9	,	,	PUNCT
bjp-22865	197	10	sano	sano	PROPN
bjp-22865	197	11	h	h	PROPN
bjp-22865	197	12	,	,	PUNCT
bjp-22865	197	13	remmers	remmer	NOUN
bjp-22865	197	14	ef	ef	PROPN
bjp-22865	197	15	,	,	PUNCT
bjp-22865	197	16	epps	epps	PROPN
bjp-22865	197	17	hr	hr	PROPN
bjp-22865	197	18	,	,	PUNCT
bjp-22865	197	19	hla	hla	PROPN
bjp-22865	197	20	t.	t.	NOUN
bjp-22865	197	21	cyclooxygenase-1	cyclooxygenase-1	PROPN
bjp-22865	197	22	and	and	CCONJ
bjp-22865	197	23	-2	-2	INTJ
bjp-22865	197	24	expression	expression	NOUN
bjp-22865	197	25	in	in	ADP
bjp-22865	197	26	rheumatoid	rheumatoid	ADJ
bjp-22865	197	27	synovial	synovial	ADJ
bjp-22865	197	28	tissues	tissue	NOUN
bjp-22865	197	29	:	:	PUNCT
bjp-22865	197	30	effects	effect	NOUN
bjp-22865	197	31	of	of	ADP
bjp-22865	197	32	interleukin1	interleukin1	NOUN
bjp-22865	197	33	beta	beta	NOUN
bjp-22865	197	34	,	,	PUNCT
bjp-22865	197	35	phorbol	phorbol	NOUN
bjp-22865	197	36	ester	ester	NOUN
bjp-22865	197	37	,	,	PUNCT
bjp-22865	197	38	and	and	CCONJ
bjp-22865	197	39	corticosteroids	corticosteroid	NOUN
bjp-22865	197	40	.	.	PUNCT
bjp-22865	198	1	j	j	PROPN
bjp-22865	198	2	clin	clin	PROPN
bjp-22865	198	3	invest	invest	PROPN
bjp-22865	198	4	.	.	PUNCT
bjp-22865	199	1	1994	1994	NUM
bjp-22865	199	2	;	;	PUNCT
bjp-22865	199	3	93	93	NUM
bjp-22865	199	4	:	:	PUNCT
bjp-22865	199	5	1095	1095	NUM
bjp-22865	199	6	-	-	SYM
bjp-22865	199	7	101	101	NUM
bjp-22865	199	8	.	.	PUNCT
bjp-22865	200	1	bangladesh	bangladesh	PROPN
bjp-22865	200	2	j	j	PROPN
bjp-22865	200	3	pharmacol	pharmacol	PROPN
bjp-22865	200	4	2015	2015	NUM
bjp-22865	200	5	;	;	PUNCT
bjp-22865	200	6	10	10	NUM
bjp-22865	200	7	:	:	PUNCT
bjp-22865	200	8	714	714	NUM
bjp-22865	200	9	-	-	SYM
bjp-22865	200	10	725	725	NUM
bjp-22865	200	11	723	723	NUM
bjp-22865	200	12	http://www.ncbi.nlm.nih.gov/pubmed/?term=chen%20zt%5bauthor%5d&cauthor=true&cauthor_uid=22980779	http://www.ncbi.nlm.nih.gov/pubmed/?term=chen%20zt%5bauthor%5d&cauthor=true&cauthor_uid=22980779	ADJ
bjp-22865	200	13	http://www.ncbi.nlm.nih.gov/pubmed/?term=chu%20hl%5bauthor%5d&cauthor=true&cauthor_uid=22980779	http://www.ncbi.nlm.nih.gov/pubmed/?term=chu%20hl%5bauthor%5d&cauthor=true&cauthor_uid=22980779	NOUN
bjp-22865	201	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=chyau%20cc%5bauthor%5d&cauthor=true&cauthor_uid=22980779	http://www.ncbi.nlm.nih.gov/pubmed/?term=chyau%20cc%5bauthor%5d&cauthor=true&cauthor_uid=22980779	X
bjp-22865	201	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=chu%20cc%5bauthor%5d&cauthor=true&cauthor_uid=22980779	http://www.ncbi.nlm.nih.gov/pubmed/?term=chu%20cc%5bauthor%5d&cauthor=true&cauthor_uid=22980779	VERB
bjp-22865	201	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=duh%20pd%5bauthor%5d&cauthor=true&cauthor_uid=22980779	http://www.ncbi.nlm.nih.gov/pubmed/?term=duh%20pd%5bauthor%5d&cauthor=true&cauthor_uid=22980779	PROPN
bjp-22865	201	4	http://www.ncbi.nlm.nih.gov/pubmed/22980779	http://www.ncbi.nlm.nih.gov/pubmed/22980779	PROPN
bjp-22865	201	5	datla	datla	VERB
bjp-22865	201	6	kp	kp	PROPN
bjp-22865	201	7	,	,	PUNCT
bjp-22865	201	8	christidou	christidou	NOUN
bjp-22865	201	9	m	m	PROPN
bjp-22865	201	10	,	,	PUNCT
bjp-22865	201	11	widmer	widmer	PROPN
bjp-22865	201	12	ww	ww	PROPN
bjp-22865	201	13	,	,	PUNCT
bjp-22865	201	14	rooprai	rooprai	PROPN
bjp-22865	201	15	hk	hk	PROPN
bjp-22865	201	16	,	,	PUNCT
bjp-22865	201	17	dexter	dexter	PROPN
bjp-22865	201	18	dt	dt	PROPN
bjp-22865	201	19	.	.	PUNCT
bjp-22865	201	20	tissue	tissue	NOUN
bjp-22865	201	21	distribution	distribution	NOUN
bjp-22865	201	22	and	and	CCONJ
bjp-22865	201	23	neuroprotective	neuroprotective	ADJ
bjp-22865	201	24	effects	effect	NOUN
bjp-22865	201	25	of	of	ADP
bjp-22865	201	26	citrus	citrus	NOUN
bjp-22865	201	27	flavonoid	flavonoid	NOUN
bjp-22865	201	28	tangeretin	tangeretin	VERB
bjp-22865	201	29	in	in	ADP
bjp-22865	201	30	a	a	DET
bjp-22865	201	31	rat	rat	NOUN
bjp-22865	201	32	model	model	NOUN
bjp-22865	201	33	of	of	ADP
bjp-22865	201	34	parkinson	parkinson	NOUN
bjp-22865	201	35	's	's	PART
bjp-22865	201	36	disease	disease	NOUN
bjp-22865	201	37	.	.	PUNCT
bjp-22865	202	1	neuroreport	neuroreport	NOUN
bjp-22865	202	2	.	.	PUNCT
bjp-22865	203	1	2001	2001	NUM
bjp-22865	203	2	;	;	PUNCT
bjp-22865	203	3	12	12	NUM
bjp-22865	203	4	:	:	SYM
bjp-22865	203	5	3871	3871	NUM
bjp-22865	203	6	-	-	SYM
bjp-22865	203	7	75	75	NUM
bjp-22865	203	8	.	.	PUNCT
bjp-22865	204	1	dong	dong	PROPN
bjp-22865	204	2	c	c	PROPN
bjp-22865	204	3	,	,	PUNCT
bjp-22865	204	4	davis	davis	PROPN
bjp-22865	204	5	rj	rj	PROPN
bjp-22865	204	6	,	,	PUNCT
bjp-22865	204	7	flavell	flavell	PROPN
bjp-22865	204	8	ra	ra	PROPN
bjp-22865	204	9	.	.	PUNCT
bjp-22865	205	1	mapkinases	mapkinase	NOUN
bjp-22865	205	2	in	in	ADP
bjp-22865	205	3	the	the	DET
bjp-22865	205	4	immune	immune	ADJ
bjp-22865	205	5	response	response	NOUN
bjp-22865	205	6	.	.	PUNCT
bjp-22865	206	1	annu	annu	PROPN
bjp-22865	206	2	rev	rev	VERB
bjp-22865	206	3	immunol	immunol	NOUN
bjp-22865	206	4	.	.	PUNCT
bjp-22865	207	1	2002	2002	NUM
bjp-22865	207	2	;	;	PUNCT
bjp-22865	207	3	20	20	NUM
bjp-22865	207	4	:	:	SYM
bjp-22865	207	5	55	55	NUM
bjp-22865	207	6	-	-	SYM
bjp-22865	207	7	72	72	NUM
bjp-22865	207	8	.	.	PUNCT
bjp-22865	208	1	dong	dong	PROPN
bjp-22865	208	2	y	y	PROPN
bjp-22865	208	3	,	,	PUNCT
bjp-22865	208	4	cao	cao	PROPN
bjp-22865	208	5	a	a	PROPN
bjp-22865	208	6	,	,	PUNCT
bjp-22865	208	7	shi	shi	PROPN
bjp-22865	208	8	j	j	PROPN
bjp-22865	208	9	,	,	PUNCT
bjp-22865	208	10	yin	yin	PROPN
bjp-22865	208	11	p	p	X
bjp-22865	208	12	,	,	PUNCT
bjp-22865	208	13	wang	wang	PROPN
bjp-22865	208	14	l	l	PROPN
bjp-22865	208	15	,	,	PUNCT
bjp-22865	208	16	ji	ji	PROPN
bjp-22865	208	17	g	g	PROPN
bjp-22865	208	18	,	,	PUNCT
bjp-22865	209	1	xie	xie	PROPN
bjp-22865	209	2	j	j	PROPN
bjp-22865	209	3	,	,	PUNCT
bjp-22865	209	4	wu	wu	PROPN
bjp-22865	209	5	d.	d.	PROPN
bjp-22865	209	6	tangeretin	tangeretin	PROPN
bjp-22865	209	7	,	,	PUNCT
bjp-22865	209	8	a	a	DET
bjp-22865	209	9	citrus	citrus	NOUN
bjp-22865	209	10	polymethoxyflavonoid	polymethoxyflavonoid	NOUN
bjp-22865	209	11	,	,	PUNCT
bjp-22865	209	12	induces	induce	VERB
bjp-22865	209	13	apoptosis	apoptosis	NOUN
bjp-22865	209	14	of	of	ADP
bjp-22865	209	15	human	human	ADJ
bjp-22865	209	16	gastric	gastric	ADJ
bjp-22865	209	17	cancer	cancer	NOUN
bjp-22865	209	18	ags	ag	NOUN
bjp-22865	209	19	cells	cell	NOUN
bjp-22865	209	20	through	through	ADP
bjp-22865	209	21	extrinsic	extrinsic	ADJ
bjp-22865	209	22	and	and	CCONJ
bjp-22865	209	23	intrinsic	intrinsic	ADJ
bjp-22865	209	24	signaling	signal	VERB
bjp-22865	209	25	pathways	pathway	NOUN
bjp-22865	209	26	.	.	PUNCT
bjp-22865	210	1	oncol	oncol	PROPN
bjp-22865	210	2	rep	rep	PROPN
bjp-22865	210	3	.	.	PROPN
bjp-22865	210	4	2014	2014	NUM
bjp-22865	210	5	;	;	PUNCT
bjp-22865	210	6	31	31	NUM
bjp-22865	210	7	:	:	SYM
bjp-22865	210	8	178894	178894	NUM
bjp-22865	210	9	.	.	PUNCT
bjp-22865	211	1	feldmann	feldmann	PROPN
bjp-22865	211	2	m	m	PROPN
bjp-22865	211	3	,	,	PUNCT
bjp-22865	211	4	brennan	brennan	PROPN
bjp-22865	211	5	fm	fm	PROPN
bjp-22865	211	6	,	,	PUNCT
bjp-22865	211	7	maini	maini	PROPN
bjp-22865	211	8	rn	rn	PROPN
bjp-22865	211	9	.	.	PROPN
bjp-22865	211	10	role	role	NOUN
bjp-22865	211	11	of	of	ADP
bjp-22865	211	12	cytokines	cytokine	NOUN
bjp-22865	211	13	in	in	ADP
bjp-22865	211	14	rheumatoid	rheumatoid	NOUN
bjp-22865	211	15	arthritis	arthritis	NOUN
bjp-22865	211	16	.	.	PUNCT
bjp-22865	212	1	annu	annu	PROPN
bjp-22865	212	2	rev	rev	VERB
bjp-22865	212	3	immunol	immunol	NOUN
bjp-22865	212	4	.	.	PUNCT
bjp-22865	212	5	1996	1996	NUM
bjp-22865	212	6	;	;	PUNCT
bjp-22865	212	7	14	14	NUM
bjp-22865	212	8	:	:	SYM
bjp-22865	212	9	397	397	NUM
bjp-22865	212	10	-	-	SYM
bjp-22865	212	11	440	440	NUM
bjp-22865	212	12	.	.	PUNCT
bjp-22865	213	1	gitter	gitter	PROPN
bjp-22865	213	2	bd	bd	PROPN
bjp-22865	213	3	,	,	PUNCT
bjp-22865	213	4	labus	labus	PROPN
bjp-22865	213	5	jm	jm	PROPN
bjp-22865	213	6	,	,	PUNCT
bjp-22865	213	7	lees	lee	NOUN
bjp-22865	213	8	sl	sl	VERB
bjp-22865	213	9	,	,	PUNCT
bjp-22865	213	10	scheetz	scheetz	VERB
bjp-22865	213	11	me	i	PRON
bjp-22865	213	12	.	.	PUNCT
bjp-22865	214	1	characteristics	characteristic	NOUN
bjp-22865	214	2	of	of	ADP
bjp-22865	214	3	human	human	ADJ
bjp-22865	214	4	synovial	synovial	ADJ
bjp-22865	214	5	fibroblast	fibroblast	ADJ
bjp-22865	214	6	activation	activation	NOUN
bjp-22865	214	7	by	by	ADP
bjp-22865	214	8	il-1	il-1	ADP
bjp-22865	214	9	beta	beta	NOUN
bjp-22865	214	10	and	and	CCONJ
bjp-22865	214	11	tnf	tnf	PROPN
bjp-22865	214	12	alpha	alpha	PROPN
bjp-22865	214	13	.	.	PUNCT
bjp-22865	215	1	immunology	immunology	NOUN
bjp-22865	215	2	1989	1989	NUM
bjp-22865	215	3	;	;	PUNCT
bjp-22865	215	4	66	66	NUM
bjp-22865	215	5	:	:	SYM
bjp-22865	215	6	196	196	NUM
bjp-22865	215	7	-	-	SYM
bjp-22865	215	8	200	200	NUM
bjp-22865	215	9	.	.	PUNCT
bjp-22865	216	1	han	han	PROPN
bjp-22865	216	2	z	z	PROPN
bjp-22865	216	3	,	,	PUNCT
bjp-22865	216	4	boyle	boyle	PROPN
bjp-22865	216	5	dl	dl	PROPN
bjp-22865	216	6	,	,	PUNCT
bjp-22865	216	7	chang	chang	PROPN
bjp-22865	216	8	l	l	PROPN
bjp-22865	216	9	,	,	PUNCT
bjp-22865	216	10	bennett	bennett	PROPN
bjp-22865	216	11	b	b	PROPN
bjp-22865	216	12	,	,	PUNCT
bjp-22865	216	13	karin	karin	PROPN
bjp-22865	216	14	m	m	PROPN
bjp-22865	216	15	,	,	PUNCT
bjp-22865	216	16	yang	yang	PROPN
bjp-22865	216	17	l	l	PROPN
bjp-22865	216	18	,	,	PUNCT
bjp-22865	216	19	manning	man	VERB
bjp-22865	216	20	am	am	NOUN
bjp-22865	216	21	,	,	PUNCT
bjp-22865	216	22	firestein	firestein	PROPN
bjp-22865	216	23	gs	gs	PROPN
bjp-22865	216	24	.	.	PUNCT
bjp-22865	216	25	c‑jun	c‑jun	PUNCT
bjp-22865	216	26	n‑terminal	n‑terminal	PROPN
bjp-22865	216	27	kinase	kinase	PROPN
bjp-22865	216	28	is	be	AUX
bjp-22865	216	29	required	require	VERB
bjp-22865	216	30	for	for	ADP
bjp-22865	216	31	metalloproteinase	metalloproteinase	NOUN
bjp-22865	216	32	expression	expression	NOUN
bjp-22865	216	33	and	and	CCONJ
bjp-22865	216	34	joint	joint	ADJ
bjp-22865	216	35	destruction	destruction	NOUN
bjp-22865	216	36	in	in	ADP
bjp-22865	216	37	inflammatory	inflammatory	ADJ
bjp-22865	216	38	arthritis	arthritis	NOUN
bjp-22865	216	39	.	.	PUNCT
bjp-22865	217	1	j	j	PROPN
bjp-22865	217	2	clin	clin	PROPN
bjp-22865	217	3	invest	invest	PROPN
bjp-22865	217	4	.	.	PUNCT
bjp-22865	218	1	2001	2001	NUM
bjp-22865	218	2	;	;	PUNCT
bjp-22865	218	3	108	108	NUM
bjp-22865	218	4	:	:	PUNCT
bjp-22865	219	1	73‑81	73‑81	NUM
bjp-22865	219	2	.	.	PUNCT
bjp-22865	219	3	han	han	PROPN
bjp-22865	219	4	mk	mk	PROPN
bjp-22865	219	5	,	,	PUNCT
bjp-22865	219	6	kim	kim	PROPN
bjp-22865	219	7	js	js	PROPN
bjp-22865	219	8	,	,	PUNCT
bjp-22865	219	9	park	park	NOUN
bjp-22865	219	10	bh	bh	PROPN
bjp-22865	219	11	,	,	PUNCT
bjp-22865	219	12	kim	kim	PROPN
bjp-22865	219	13	jr	jr	PROPN
bjp-22865	219	14	,	,	PUNCT
bjp-22865	219	15	hwang	hwang	PROPN
bjp-22865	219	16	by	by	ADP
bjp-22865	219	17	,	,	PUNCT
bjp-22865	219	18	lee	lee	PROPN
bjp-22865	219	19	hy	hy	PROPN
bjp-22865	219	20	,	,	PUNCT
bjp-22865	219	21	song	song	PROPN
bjp-22865	219	22	ek	ek	PROPN
bjp-22865	219	23	,	,	PUNCT
bjp-22865	219	24	yoo	yoo	PROPN
bjp-22865	219	25	wh	wh	PROPN
bjp-22865	219	26	.	.	PROPN
bjp-22865	219	27	nf	nf	NOUN
bjp-22865	219	28	-	-	PUNCT
bjp-22865	219	29	kappab	kappab	NOUN
bjp-22865	219	30	dependent	dependent	ADJ
bjp-22865	219	31	lymphocyte	lymphocyte	ADJ
bjp-22865	219	32	hyperadhesiveness	hyperadhesiveness	NOUN
bjp-22865	219	33	to	to	ADP
bjp-22865	219	34	synovial	synovial	ADJ
bjp-22865	219	35	fibroblasts	fibroblast	NOUN
bjp-22865	219	36	by	by	ADP
bjp-22865	219	37	hypoxia	hypoxia	NOUN
bjp-22865	219	38	and	and	CCONJ
bjp-22865	219	39	reoxygenation	reoxygenation	NOUN
bjp-22865	219	40	:	:	PUNCT
bjp-22865	219	41	potential	potential	ADJ
bjp-22865	219	42	role	role	NOUN
bjp-22865	219	43	in	in	ADP
bjp-22865	219	44	rheumatoid	rheumatoid	NOUN
bjp-22865	219	45	arthritis	arthritis	NOUN
bjp-22865	219	46	.	.	PUNCT
bjp-22865	220	1	j	j	PROPN
bjp-22865	220	2	leukocyte	leukocyte	PROPN
bjp-22865	220	3	biol	biol	NOUN
bjp-22865	220	4	.	.	PUNCT
bjp-22865	221	1	2003	2003	NUM
bjp-22865	221	2	;	;	PUNCT
bjp-22865	221	3	73	73	NUM
bjp-22865	221	4	:	:	SYM
bjp-22865	221	5	525	525	NUM
bjp-22865	221	6	-	-	SYM
bjp-22865	221	7	29	29	NUM
bjp-22865	221	8	.	.	PUNCT
bjp-22865	222	1	ho	ho	PROPN
bjp-22865	222	2	sc	sc	PROPN
bjp-22865	222	3	,	,	PUNCT
bjp-22865	222	4	kuo	kuo	PROPN
bjp-22865	222	5	ct	ct	PROPN
bjp-22865	222	6	.	.	PUNCT
bjp-22865	223	1	hesperidin	hesperidin	PROPN
bjp-22865	223	2	,	,	PUNCT
bjp-22865	223	3	nobiletin	nobiletin	NOUN
bjp-22865	223	4	,	,	PUNCT
bjp-22865	223	5	and	and	CCONJ
bjp-22865	223	6	tangeretin	tangeretin	X
bjp-22865	223	7	are	be	AUX
bjp-22865	223	8	collectively	collectively	ADV
bjp-22865	223	9	responsible	responsible	ADJ
bjp-22865	223	10	for	for	ADP
bjp-22865	223	11	the	the	DET
bjp-22865	223	12	anti	anti	ADJ
bjp-22865	223	13	-	-	ADJ
bjp-22865	223	14	neuroinflammatory	neuroinflammatory	ADJ
bjp-22865	223	15	capacity	capacity	NOUN
bjp-22865	223	16	of	of	ADP
bjp-22865	223	17	tangerine	tangerine	ADJ
bjp-22865	223	18	peel	peel	NOUN
bjp-22865	223	19	(	(	PUNCT
bjp-22865	223	20	citri	citri	ADJ
bjp-22865	223	21	reticulatae	reticulatae	NOUN
bjp-22865	223	22	pericarpium	pericarpium	NOUN
bjp-22865	223	23	)	)	PUNCT
bjp-22865	223	24	.	.	PUNCT
bjp-22865	224	1	food	food	NOUN
bjp-22865	224	2	chem	chem	PROPN
bjp-22865	224	3	toxicol	toxicol	NOUN
bjp-22865	224	4	.	.	PUNCT
bjp-22865	224	5	2014	2014	NUM
bjp-22865	224	6	;	;	PUNCT
bjp-22865	224	7	71	71	NUM
bjp-22865	224	8	:	:	SYM
bjp-22865	224	9	176	176	NUM
bjp-22865	224	10	-	-	SYM
bjp-22865	224	11	82	82	NUM
bjp-22865	224	12	.	.	PUNCT
bjp-22865	225	1	hodgkin	hodgkin	PROPN
bjp-22865	225	2	pd	pd	PROPN
bjp-22865	225	3	,	,	PUNCT
bjp-22865	225	4	yamashita	yamashita	PROPN
bjp-22865	225	5	lc	lc	PROPN
bjp-22865	225	6	,	,	PUNCT
bjp-22865	225	7	coffman	coffman	PROPN
bjp-22865	225	8	rl	rl	PROPN
bjp-22865	225	9	,	,	PUNCT
bjp-22865	225	10	kehry	kehry	PROPN
bjp-22865	225	11	mr	mr	PROPN
bjp-22865	225	12	.	.	PROPN
bjp-22865	225	13	separation	separation	NOUN
bjp-22865	225	14	of	of	ADP
bjp-22865	225	15	events	event	NOUN
bjp-22865	225	16	mediating	mediate	VERB
bjp-22865	225	17	b	b	PRON
bjp-22865	225	18	cell	cell	NOUN
bjp-22865	225	19	proliferation	proliferation	NOUN
bjp-22865	225	20	and	and	CCONJ
bjp-22865	225	21	ig	ig	PROPN
bjp-22865	225	22	production	production	NOUN
bjp-22865	225	23	by	by	ADP
bjp-22865	225	24	using	use	VERB
bjp-22865	225	25	t	t	PROPN
bjp-22865	225	26	cell	cell	NOUN
bjp-22865	225	27	membranes	membrane	NOUN
bjp-22865	225	28	and	and	CCONJ
bjp-22865	225	29	lymphokines	lymphokine	NOUN
bjp-22865	225	30	.	.	PUNCT
bjp-22865	226	1	j	j	PROPN
bjp-22865	226	2	immunol	immunol	NOUN
bjp-22865	226	3	.	.	PUNCT
bjp-22865	226	4	1990	1990	NUM
bjp-22865	226	5	;	;	PUNCT
bjp-22865	226	6	145	145	NUM
bjp-22865	226	7	:	:	PUNCT
bjp-22865	226	8	2025	2025	NUM
bjp-22865	226	9	-	-	SYM
bjp-22865	226	10	34	34	NUM
bjp-22865	226	11	.	.	PUNCT
bjp-22865	227	1	jackson	jackson	PROPN
bjp-22865	227	2	c	c	PROPN
bjp-22865	227	3	,	,	PUNCT
bjp-22865	227	4	nguyen	nguyen	PROPN
bjp-22865	227	5	m	m	PROPN
bjp-22865	227	6	,	,	PUNCT
bjp-22865	227	7	arkell	arkell	PROPN
bjp-22865	227	8	j	j	PROPN
bjp-22865	227	9	,	,	PUNCT
bjp-22865	227	10	sambrook	sambrook	PROPN
bjp-22865	227	11	p.	p.	NOUN
bjp-22865	227	12	selective	selective	ADJ
bjp-22865	227	13	matrix	matrix	NOUN
bjp-22865	227	14	metalloproteinase	metalloproteinase	NOUN
bjp-22865	227	15	(	(	PUNCT
bjp-22865	227	16	mmp	mmp	PROPN
bjp-22865	227	17	)	)	PUNCT
bjp-22865	227	18	inhibition	inhibition	NOUN
bjp-22865	227	19	in	in	ADP
bjp-22865	227	20	rheumatoid	rheumatoid	NOUN
bjp-22865	227	21	arthritis	arthritis	NOUN
bjp-22865	227	22	–	–	PUNCT
bjp-22865	227	23	targetting	targette	VERB
bjp-22865	227	24	gelatinase	gelatinase	NOUN
bjp-22865	227	25	a	a	DET
bjp-22865	227	26	activation	activation	NOUN
bjp-22865	227	27	.	.	PUNCT
bjp-22865	228	1	inflamm	inflamm	PROPN
bjp-22865	228	2	res	res	PROPN
bjp-22865	228	3	.	.	PUNCT
bjp-22865	228	4	2001	2001	NUM
bjp-22865	228	5	;	;	PUNCT
bjp-22865	228	6	50	50	NUM
bjp-22865	228	7	:	:	SYM
bjp-22865	228	8	183	183	NUM
bjp-22865	228	9	-86	-86	PROPN
bjp-22865	228	10	.	.	PUNCT
bjp-22865	229	1	karin	karin	PROPN
bjp-22865	229	2	m	m	PROPN
bjp-22865	229	3	,	,	PUNCT
bjp-22865	229	4	lin	lin	PROPN
bjp-22865	229	5	a.	a.	PROPN
bjp-22865	229	6	nf	nf	PROPN
bjp-22865	229	7	-	-	PUNCT
bjp-22865	229	8	kappab	kappab	NOUN
bjp-22865	229	9	at	at	ADP
bjp-22865	229	10	the	the	DET
bjp-22865	229	11	cross	cross	ADJ
bjp-22865	229	12	roads	road	NOUN
bjp-22865	229	13	of	of	ADP
bjp-22865	229	14	life	life	NOUN
bjp-22865	229	15	and	and	CCONJ
bjp-22865	229	16	death	death	NOUN
bjp-22865	229	17	.	.	PUNCT
bjp-22865	230	1	nat	nat	PROPN
bjp-22865	230	2	immunol	immunol	NOUN
bjp-22865	230	3	.	.	PUNCT
bjp-22865	231	1	2002	2002	NUM
bjp-22865	231	2	;	;	PUNCT
bjp-22865	231	3	3	3	NUM
bjp-22865	231	4	:	:	SYM
bjp-22865	231	5	221	221	NUM
bjp-22865	231	6	-	-	SYM
bjp-22865	231	7	27	27	NUM
bjp-22865	231	8	.	.	PUNCT
bjp-22865	232	1	kim	kim	PROPN
bjp-22865	232	2	hg	hg	PROPN
bjp-22865	232	3	,	,	PUNCT
bjp-22865	232	4	shrestha	shrestha	PROPN
bjp-22865	232	5	b	b	PROPN
bjp-22865	232	6	,	,	PUNCT
bjp-22865	232	7	lim	lim	PROPN
bjp-22865	232	8	sy	sy	PROPN
bjp-22865	232	9	,	,	PUNCT
bjp-22865	232	10	yoon	yoon	PROPN
bjp-22865	232	11	dh	dh	PROPN
bjp-22865	232	12	,	,	PUNCT
bjp-22865	232	13	chang	chang	PROPN
bjp-22865	232	14	wc	wc	PROPN
bjp-22865	232	15	,	,	PUNCT
bjp-22865	232	16	shin	shin	PROPN
bjp-22865	232	17	dj	dj	PROPN
bjp-22865	232	18	,	,	PUNCT
bjp-22865	232	19	han	han	PROPN
bjp-22865	232	20	sk	sk	PROPN
bjp-22865	232	21	,	,	PUNCT
bjp-22865	232	22	park	park	NOUN
bjp-22865	232	23	sm	sm	PROPN
bjp-22865	232	24	,	,	PUNCT
bjp-22865	232	25	park	park	PROPN
bjp-22865	232	26	jh	jh	PROPN
bjp-22865	232	27	,	,	PUNCT
bjp-22865	232	28	park	park	PROPN
bjp-22865	232	29	hi	hi	PROPN
bjp-22865	232	30	,	,	PUNCT
bjp-22865	232	31	sung	sung	PROPN
bjp-22865	232	32	jm	jm	PROPN
bjp-22865	232	33	,	,	PUNCT
bjp-22865	232	34	jang	jang	PROPN
bjp-22865	232	35	y	y	PROPN
bjp-22865	232	36	,	,	PUNCT
bjp-22865	232	37	chung	chung	PROPN
bjp-22865	232	38	n	n	PROPN
bjp-22865	232	39	,	,	PUNCT
bjp-22865	232	40	hwang	hwang	PROPN
bjp-22865	232	41	kc	kc	PROPN
bjp-22865	232	42	,	,	PUNCT
bjp-22865	232	43	kim	kim	PROPN
bjp-22865	232	44	tw	tw	PROPN
bjp-22865	232	45	.	.	PUNCT
bjp-22865	233	1	cordycepin	cordycepin	PROPN
bjp-22865	233	2	inhibits	inhibit	VERB
bjp-22865	233	3	lipopolysaccharide	lipopolysaccharide	ADV
bjp-22865	233	4	-	-	PUNCT
bjp-22865	233	5	induced	induce	VERB
bjp-22865	233	6	inflammation	inflammation	NOUN
bjp-22865	233	7	by	by	ADP
bjp-22865	233	8	the	the	DET
bjp-22865	233	9	supperssion	supperssion	NOUN
bjp-22865	233	10	of	of	ADP
bjp-22865	233	11	nf	nf	NOUN
bjp-22865	233	12	-	-	PUNCT
bjp-22865	233	13	kb	kb	NOUN
bjp-22865	233	14	through	through	ADP
bjp-22865	233	15	akt	akt	PROPN
bjp-22865	233	16	and	and	CCONJ
bjp-22865	233	17	p38	p38	VERB
bjp-22865	233	18	inhibition	inhibition	NOUN
bjp-22865	233	19	in	in	ADP
bjp-22865	233	20	raw	raw	ADJ
bjp-22865	233	21	264.7	264.7	NUM
bjp-22865	233	22	macrophage	macrophage	ADJ
bjp-22865	233	23	cells	cell	NOUN
bjp-22865	233	24	.	.	PUNCT
bjp-22865	234	1	eur	eur	PROPN
bjp-22865	234	2	j	j	PROPN
bjp-22865	234	3	pharmacol	pharmacol	PROPN
bjp-22865	234	4	.	.	PUNCT
bjp-22865	235	1	2006	2006	NUM
bjp-22865	235	2	;	;	PUNCT
bjp-22865	235	3	545	545	NUM
bjp-22865	235	4	:	:	SYM
bjp-22865	235	5	192	192	NUM
bjp-22865	235	6	-	-	SYM
bjp-22865	235	7	99	99	NUM
bjp-22865	235	8	.	.	PUNCT
bjp-22865	236	1	knauper	knauper	PROPN
bjp-22865	236	2	v	v	NOUN
bjp-22865	236	3	,	,	PUNCT
bjp-22865	236	4	lopez	lopez	NOUN
bjp-22865	236	5	-	-	PUNCT
bjp-22865	236	6	otin	otin	NOUN
bjp-22865	236	7	c	c	NOUN
bjp-22865	236	8	,	,	PUNCT
bjp-22865	236	9	smith	smith	PROPN
bjp-22865	236	10	b	b	PROPN
bjp-22865	236	11	,	,	PUNCT
bjp-22865	236	12	knight	knight	NOUN
bjp-22865	236	13	g	g	PROPN
bjp-22865	236	14	,	,	PUNCT
bjp-22865	236	15	murphy	murphy	PROPN
bjp-22865	236	16	g.	g.	PROPN
bjp-22865	237	1	biochemical	biochemical	ADJ
bjp-22865	237	2	characterization	characterization	NOUN
bjp-22865	237	3	of	of	ADP
bjp-22865	237	4	human	human	ADJ
bjp-22865	237	5	collagenase-3	collagenase-3	PROPN
bjp-22865	237	6	.	.	PROPN
bjp-22865	237	7	j	j	PROPN
bjp-22865	237	8	biol	biol	PROPN
bjp-22865	237	9	chem	chem	NOUN
bjp-22865	237	10	.	.	PUNCT
bjp-22865	238	1	1996	1996	NUM
bjp-22865	238	2	;	;	PUNCT
bjp-22865	238	3	271	271	NUM
bjp-22865	238	4	:	:	PUNCT
bjp-22865	238	5	1544	1544	NUM
bjp-22865	238	6	-	-	SYM
bjp-22865	238	7	50	50	NUM
bjp-22865	238	8	.	.	PUNCT
bjp-22865	239	1	konttinen	konttinen	PROPN
bjp-22865	239	2	yt	yt	PROPN
bjp-22865	239	3	,	,	PUNCT
bjp-22865	239	4	ainola	ainola	PROPN
bjp-22865	239	5	m	m	PROPN
bjp-22865	239	6	,	,	PUNCT
bjp-22865	239	7	valleala	valleala	PROPN
bjp-22865	239	8	h	h	NOUN
bjp-22865	239	9	,	,	PUNCT
bjp-22865	239	10	ma	ma	PROPN
bjp-22865	239	11	j	j	PROPN
bjp-22865	239	12	,	,	PUNCT
bjp-22865	239	13	ida	ida	PROPN
bjp-22865	239	14	h	h	PROPN
bjp-22865	239	15	,	,	PUNCT
bjp-22865	239	16	mandelin	mandelin	PROPN
bjp-22865	239	17	j	j	PROPN
bjp-22865	239	18	,	,	PUNCT
bjp-22865	239	19	kinne	kinne	PROPN
bjp-22865	239	20	rw	rw	PROPN
bjp-22865	239	21	,	,	PUNCT
bjp-22865	239	22	santavirta	santavirta	PROPN
bjp-22865	239	23	s	s	PROPN
bjp-22865	239	24	,	,	PUNCT
bjp-22865	239	25	sorsa	sorsa	PROPN
bjp-22865	239	26	t	t	PROPN
bjp-22865	239	27	,	,	PUNCT
bjp-22865	239	28	lópez	lópez	NOUN
bjp-22865	239	29	-	-	PUNCT
bjp-22865	239	30	otín	otín	NOUN
bjp-22865	239	31	c	c	NOUN
bjp-22865	239	32	,	,	PUNCT
bjp-22865	239	33	takagi	takagi	PROPN
bjp-22865	239	34	m.	m.	NOUN
bjp-22865	239	35	analysis	analysis	NOUN
bjp-22865	239	36	of	of	ADP
bjp-22865	239	37	16	16	NUM
bjp-22865	239	38	different	different	ADJ
bjp-22865	239	39	matrix	matrix	NOUN
bjp-22865	239	40	metalloproteinases	metalloproteinase	NOUN
bjp-22865	239	41	(	(	PUNCT
bjp-22865	239	42	mmp-1	mmp-1	NOUN
bjp-22865	239	43	to	to	ADP
bjp-22865	239	44	mmp-20	mmp-20	NUM
bjp-22865	239	45	)	)	PUNCT
bjp-22865	239	46	in	in	ADP
bjp-22865	239	47	the	the	DET
bjp-22865	239	48	synovial	synovial	ADJ
bjp-22865	239	49	membrane	membrane	NOUN
bjp-22865	239	50	:	:	PUNCT
bjp-22865	239	51	different	different	ADJ
bjp-22865	239	52	profiles	profile	NOUN
bjp-22865	239	53	in	in	ADP
bjp-22865	239	54	trauma	trauma	NOUN
bjp-22865	239	55	and	and	CCONJ
bjp-22865	239	56	rheumatoid	rheumatoid	VERB
bjp-22865	239	57	arthritis	arthritis	NOUN
bjp-22865	239	58	.	.	PUNCT
bjp-22865	240	1	ann	ann	PROPN
bjp-22865	240	2	rheum	rheum	PROPN
bjp-22865	240	3	dis	dis	PROPN
bjp-22865	240	4	.	.	PUNCT
bjp-22865	240	5	1999	1999	NUM
bjp-22865	240	6	;	;	PUNCT
bjp-22865	240	7	58	58	NUM
bjp-22865	240	8	:	:	PUNCT
bjp-22865	240	9	691	691	NUM
bjp-22865	240	10	-	-	SYM
bjp-22865	240	11	97	97	NUM
bjp-22865	240	12	.	.	PUNCT
bjp-22865	241	1	lee	lee	PROPN
bjp-22865	241	2	hy	hy	PROPN
bjp-22865	241	3	,	,	PUNCT
bjp-22865	241	4	jeon	jeon	PROPN
bjp-22865	241	5	hs	hs	PROPN
bjp-22865	241	6	,	,	PUNCT
bjp-22865	241	7	song	song	PROPN
bjp-22865	241	8	ek	ek	PROPN
bjp-22865	241	9	,	,	PUNCT
bjp-22865	241	10	han	han	PROPN
bjp-22865	241	11	mk	mk	PROPN
bjp-22865	241	12	,	,	PUNCT
bjp-22865	241	13	park	park	NOUN
bjp-22865	241	14	si	si	PROPN
bjp-22865	241	15	,	,	PUNCT
bjp-22865	241	16	lee	lee	PROPN
bjp-22865	241	17	si	si	PROPN
bjp-22865	241	18	,	,	PUNCT
bjp-22865	241	19	yun	yun	PROPN
bjp-22865	241	20	hj	hj	PROPN
bjp-22865	241	21	,	,	PUNCT
bjp-22865	241	22	kim	kim	PROPN
bjp-22865	241	23	jr	jr	PROPN
bjp-22865	241	24	,	,	PUNCT
bjp-22865	241	25	kim	kim	PROPN
bjp-22865	241	26	js	js	PROPN
bjp-22865	241	27	,	,	PUNCT
bjp-22865	241	28	lee	lee	PROPN
bjp-22865	241	29	yc	yc	PROPN
bjp-22865	241	30	,	,	PUNCT
bjp-22865	241	31	kim	kim	PROPN
bjp-22865	241	32	si	si	PROPN
bjp-22865	241	33	,	,	PUNCT
bjp-22865	241	34	kim	kim	PROPN
bjp-22865	241	35	hr	hr	PROPN
bjp-22865	241	36	,	,	PUNCT
bjp-22865	241	37	choi	choi	PROPN
bjp-22865	241	38	jy	jy	PROPN
bjp-22865	241	39	,	,	PUNCT
bjp-22865	241	40	kang	kang	PROPN
bjp-22865	241	41	i	i	PROPN
bjp-22865	241	42	,	,	PUNCT
bjp-22865	241	43	kim	kim	PROPN
bjp-22865	241	44	hy	hy	PROPN
bjp-22865	241	45	,	,	PUNCT
bjp-22865	241	46	yoo	yoo	PROPN
bjp-22865	241	47	wh	wh	PROPN
bjp-22865	241	48	.	.	PUNCT
bjp-22865	242	1	cd40	cd40	PROPN
bjp-22865	242	2	ligation	ligation	NOUN
bjp-22865	242	3	of	of	ADP
bjp-22865	242	4	rheumatoid	rheumatoid	NOUN
bjp-22865	242	5	synovial	synovial	ADJ
bjp-22865	242	6	fibroblasts	fibroblast	NOUN
bjp-22865	242	7	regulates	regulate	VERB
bjp-22865	242	8	rankl	rankl	NOUN
bjp-22865	242	9	-	-	PUNCT
bjp-22865	242	10	mediated	mediate	VERB
bjp-22865	242	11	osteoclastogenesis	osteoclastogenesis	NOUN
bjp-22865	242	12	:	:	PUNCT
bjp-22865	242	13	evidence	evidence	NOUN
bjp-22865	242	14	of	of	ADP
bjp-22865	242	15	nf	nf	ADJ
bjp-22865	242	16	-	-	PUNCT
bjp-22865	242	17	kappab	kappab	NOUN
bjp-22865	242	18	-	-	PUNCT
bjp-22865	242	19	dependent	dependent	ADJ
bjp-22865	242	20	,	,	PUNCT
bjp-22865	242	21	cd40	cd40	PROPN
bjp-22865	242	22	-	-	PUNCT
bjp-22865	242	23	mediated	mediate	VERB
bjp-22865	242	24	bone	bone	NOUN
bjp-22865	242	25	destruction	destruction	NOUN
bjp-22865	242	26	in	in	ADP
bjp-22865	242	27	rheumatoid	rheumatoid	NOUN
bjp-22865	242	28	arthritis	arthritis	NOUN
bjp-22865	242	29	.	.	PUNCT
bjp-22865	243	1	arthritis	arthritis	NOUN
bjp-22865	243	2	rheum	rheum	NOUN
bjp-22865	243	3	.	.	PUNCT
bjp-22865	244	1	2006	2006	NUM
bjp-22865	244	2	;	;	PUNCT
bjp-22865	244	3	54	54	NUM
bjp-22865	244	4	:	:	SYM
bjp-22865	244	5	1747	1747	NUM
bjp-22865	244	6	-	-	SYM
bjp-22865	244	7	58	58	NUM
bjp-22865	244	8	.	.	PUNCT
bjp-22865	245	1	lie	lie	VERB
bjp-22865	245	2	pp	pp	ADV
bjp-22865	245	3	,	,	PUNCT
bjp-22865	245	4	cheng	cheng	PROPN
bjp-22865	245	5	cy	cy	PROPN
bjp-22865	245	6	,	,	PUNCT
bjp-22865	245	7	mruk	mruk	PROPN
bjp-22865	245	8	dd	dd	PROPN
bjp-22865	245	9	.	.	PUNCT
bjp-22865	246	1	the	the	DET
bjp-22865	246	2	biology	biology	NOUN
bjp-22865	246	3	of	of	ADP
bjp-22865	246	4	interleukin-1	interleukin-1	PROPN
bjp-22865	246	5	:	:	PUNCT
bjp-22865	246	6	emerging	emerge	VERB
bjp-22865	246	7	concepts	concept	NOUN
bjp-22865	246	8	in	in	ADP
bjp-22865	246	9	the	the	DET
bjp-22865	246	10	regulation	regulation	NOUN
bjp-22865	246	11	of	of	ADP
bjp-22865	246	12	the	the	DET
bjp-22865	246	13	actin	actin	NOUN
bjp-22865	246	14	cytoskeleton	cytoskeleton	PROPN
bjp-22865	246	15	and	and	CCONJ
bjp-22865	246	16	cell	cell	NOUN
bjp-22865	246	17	junction	junction	NOUN
bjp-22865	246	18	dynamics	dynamic	NOUN
bjp-22865	246	19	.	.	PUNCT
bjp-22865	247	1	cell	cell	NOUN
bjp-22865	247	2	mol	mol	ADP
bjp-22865	247	3	life	life	PROPN
bjp-22865	247	4	sci	sci	PROPN
bjp-22865	247	5	.	.	PROPN
bjp-22865	247	6	2012	2012	NUM
bjp-22865	247	7	;	;	PUNCT
bjp-22865	247	8	69	69	NUM
bjp-22865	247	9	:	:	SYM
bjp-22865	247	10	487	487	NUM
bjp-22865	247	11	-	-	SYM
bjp-22865	247	12	500	500	NUM
bjp-22865	247	13	.	.	PUNCT
bjp-22865	248	1	luo	luo	PROPN
bjp-22865	248	2	sf	sf	PROPN
bjp-22865	248	3	,	,	PUNCT
bjp-22865	248	4	fang	fang	PROPN
bjp-22865	248	5	ry	ry	PROPN
bjp-22865	248	6	,	,	PUNCT
bjp-22865	248	7	hsieh	hsieh	PROPN
bjp-22865	248	8	hl	hl	NOUN
bjp-22865	248	9	,	,	PUNCT
bjp-22865	248	10	chi	chi	PROPN
bjp-22865	248	11	pl	pl	PROPN
bjp-22865	248	12	,	,	PUNCT
bjp-22865	248	13	lin	lin	PROPN
bjp-22865	248	14	cc	cc	PROPN
bjp-22865	248	15	,	,	PUNCT
bjp-22865	248	16	hsiao	hsiao	PROPN
bjp-22865	248	17	ld	ld	PROPN
bjp-22865	248	18	,	,	PUNCT
bjp-22865	248	19	wu	wu	PROPN
bjp-22865	248	20	cc	cc	PROPN
bjp-22865	248	21	,	,	PUNCT
bjp-22865	248	22	wang	wang	PROPN
bjp-22865	248	23	js	js	PROPN
bjp-22865	248	24	,	,	PUNCT
bjp-22865	248	25	yang	yang	PROPN
bjp-22865	248	26	cm	cm	PROPN
bjp-22865	248	27	.	.	PUNCT
bjp-22865	249	1	involvement	involvement	NOUN
bjp-22865	249	2	of	of	ADP
bjp-22865	249	3	mapks	mapks	NOUN
bjp-22865	249	4	and	and	CCONJ
bjp-22865	249	5	nfkappab	nfkappab	NOUN
bjp-22865	249	6	in	in	ADP
bjp-22865	249	7	tumor	tumor	NOUN
bjp-22865	249	8	necrosis	necrosis	NOUN
bjp-22865	249	9	factor	factor	NOUN
bjp-22865	249	10	alpha	alpha	NOUN
bjp-22865	249	11	-	-	PUNCT
bjp-22865	249	12	induced	induce	VERB
bjp-22865	249	13	vascular	vascular	ADJ
bjp-22865	249	14	cell	cell	NOUN
bjp-22865	249	15	adhesion	adhesion	NOUN
bjp-22865	249	16	molecule1expression	molecule1expression	NOUN
bjp-22865	249	17	in	in	ADP
bjp-22865	249	18	human	human	ADJ
bjp-22865	249	19	rheumatoid	rheumatoid	NOUN
bjp-22865	249	20	arthritis	arthritis	NOUN
bjp-22865	249	21	synovial	synovial	ADJ
bjp-22865	249	22	fibroblasts	fibroblast	NOUN
bjp-22865	249	23	.	.	PUNCT
bjp-22865	250	1	arthritis	arthritis	NOUN
bjp-22865	250	2	rheum	rheum	NOUN
bjp-22865	250	3	.	.	PUNCT
bjp-22865	251	1	2010	2010	NUM
bjp-22865	251	2	;	;	PUNCT
bjp-22865	251	3	62	62	NUM
bjp-22865	251	4	:	:	SYM
bjp-22865	251	5	10516	10516	NUM
bjp-22865	251	6	.	.	PUNCT
bjp-22865	252	1	martel	martel	NOUN
bjp-22865	252	2	-	-	PUNCT
bjp-22865	252	3	pelletier	pelletier	PROPN
bjp-22865	252	4	j	j	PROPN
bjp-22865	252	5	,	,	PUNCT
bjp-22865	252	6	pelletier	pelletier	PROPN
bjp-22865	252	7	jp	jp	PROPN
bjp-22865	252	8	,	,	PUNCT
bjp-22865	252	9	fahmi	fahmi	PROPN
bjp-22865	252	10	h.	h.	PROPN
bjp-22865	252	11	new	new	ADJ
bjp-22865	252	12	insights	insight	NOUN
bjp-22865	252	13	into	into	ADP
bjp-22865	252	14	prostaglandin	prostaglandin	ADJ
bjp-22865	252	15	biology	biology	NOUN
bjp-22865	252	16	.	.	PUNCT
bjp-22865	253	1	j	j	PROPN
bjp-22865	253	2	rheumatol	rheumatol	NOUN
bjp-22865	253	3	.	.	PUNCT
bjp-22865	254	1	2004	2004	NUM
bjp-22865	254	2	;	;	PUNCT
bjp-22865	254	3	31	31	NUM
bjp-22865	254	4	:	:	SYM
bjp-22865	254	5	14	14	NUM
bjp-22865	254	6	-	-	SYM
bjp-22865	254	7	16	16	NUM
bjp-22865	254	8	.	.	PUNCT
bjp-22865	255	1	mcintyre	mcintyre	PROPN
bjp-22865	255	2	kw	kw	PROPN
bjp-22865	255	3	,	,	PUNCT
bjp-22865	255	4	shuster	shuster	PROPN
bjp-22865	255	5	dj	dj	PROPN
bjp-22865	255	6	,	,	PUNCT
bjp-22865	255	7	gillooly	gillooly	ADJ
bjp-22865	255	8	km	km	PROPN
bjp-22865	255	9	,	,	PUNCT
bjp-22865	255	10	dambach	dambach	NOUN
bjp-22865	255	11	dm	dm	PROPN
bjp-22865	255	12	,	,	PUNCT
bjp-22865	255	13	pattoli	pattoli	NOUN
bjp-22865	255	14	ma	ma	PROPN
bjp-22865	255	15	,	,	PUNCT
bjp-22865	255	16	lu	lu	PROPN
bjp-22865	255	17	p	p	NOUN
bjp-22865	255	18	,	,	PUNCT
bjp-22865	255	19	zhou	zhou	PROPN
bjp-22865	255	20	xd	xd	PROPN
bjp-22865	255	21	,	,	PUNCT
bjp-22865	255	22	qiu	qiu	PROPN
bjp-22865	255	23	y	y	PROPN
bjp-22865	255	24	,	,	PUNCT
bjp-22865	255	25	zusi	zusi	PROPN
bjp-22865	255	26	fc	fc	PROPN
bjp-22865	255	27	,	,	PUNCT
bjp-22865	255	28	burke	burke	PROPN
bjp-22865	255	29	jr	jr	PROPN
bjp-22865	255	30	.	.	PROPN
bjp-22865	256	1	a	a	DET
bjp-22865	256	2	highly	highly	ADV
bjp-22865	256	3	selective	selective	ADJ
bjp-22865	256	4	inhibitor	inhibitor	NOUN
bjp-22865	256	5	of	of	ADP
bjp-22865	256	6	i	i	PROPN
bjp-22865	256	7	kappa	kappa	PROPN
bjp-22865	256	8	b	b	PROPN
bjp-22865	256	9	kinase	kinase	PROPN
bjp-22865	256	10	,	,	PUNCT
bjp-22865	256	11	bms‑345541	bms‑345541	PROPN
bjp-22865	256	12	,	,	PUNCT
bjp-22865	256	13	blocks	block	VERB
bjp-22865	256	14	both	both	DET
bjp-22865	256	15	joint	joint	ADJ
bjp-22865	256	16	inflammation	inflammation	NOUN
bjp-22865	256	17	and	and	CCONJ
bjp-22865	256	18	destruction	destruction	NOUN
bjp-22865	256	19	in	in	ADP
bjp-22865	256	20	collagen	collagen	NOUN
bjp-22865	256	21	-	-	PUNCT
bjp-22865	256	22	induced	induce	VERB
bjp-22865	256	23	arthritis	arthritis	NOUN
bjp-22865	256	24	in	in	ADP
bjp-22865	256	25	mice	mouse	NOUN
bjp-22865	256	26	.	.	PUNCT
bjp-22865	257	1	arthritis	arthritis	NOUN
bjp-22865	257	2	rheum	rheum	NOUN
bjp-22865	257	3	.	.	PUNCT
bjp-22865	258	1	2003	2003	NUM
bjp-22865	258	2	;	;	PUNCT
bjp-22865	258	3	48	48	NUM
bjp-22865	258	4	:	:	SYM
bjp-22865	258	5	2652‑59	2652‑59	NUM
bjp-22865	258	6	.	.	PUNCT
bjp-22865	258	7	morel	morel	PROPN
bjp-22865	258	8	j	j	PROPN
bjp-22865	258	9	,	,	PUNCT
bjp-22865	258	10	berenbaum	berenbaum	PROPN
bjp-22865	258	11	f.	f.	PROPN
bjp-22865	258	12	signal	signal	PROPN
bjp-22865	258	13	transduction	transduction	NOUN
bjp-22865	258	14	pathways	pathway	NOUN
bjp-22865	258	15	:	:	PUNCT
bjp-22865	258	16	new	new	ADJ
bjp-22865	258	17	targets	target	NOUN
bjp-22865	258	18	for	for	ADP
bjp-22865	258	19	treating	treat	VERB
bjp-22865	258	20	rheumatoid	rheumatoid	NOUN
bjp-22865	258	21	arthritis	arthritis	NOUN
bjp-22865	258	22	.	.	PUNCT
bjp-22865	259	1	joint	joint	ADJ
bjp-22865	259	2	bone	bone	NOUN
bjp-22865	259	3	spine	spine	NOUN
bjp-22865	259	4	.	.	PUNCT
bjp-22865	260	1	2004	2004	NUM
bjp-22865	260	2	;	;	PUNCT
bjp-22865	260	3	71	71	NUM
bjp-22865	260	4	:	:	PUNCT
bjp-22865	260	5	503	503	NUM
bjp-22865	260	6	-	-	SYM
bjp-22865	260	7	10	10	NUM
bjp-22865	260	8	.	.	PUNCT
bjp-22865	261	1	nishikawa	nishikawa	PROPN
bjp-22865	261	2	m	m	PROPN
bjp-22865	261	3	,	,	PUNCT
bjp-22865	261	4	myoui	myoui	VERB
bjp-22865	261	5	a	a	PRON
bjp-22865	261	6	,	,	PUNCT
bjp-22865	261	7	tomita	tomita	PROPN
bjp-22865	261	8	t	t	PROPN
bjp-22865	261	9	,	,	PUNCT
bjp-22865	261	10	takahi	takahi	PROPN
bjp-22865	261	11	k	k	PROPN
bjp-22865	261	12	,	,	PUNCT
bjp-22865	261	13	nampei	nampei	PROPN
bjp-22865	261	14	a	a	PROPN
bjp-22865	261	15	and	and	CCONJ
bjp-22865	261	16	yoshikawa	yoshikawa	PROPN
bjp-22865	261	17	h.	h.	PROPN
bjp-22865	261	18	prevention	prevention	PROPN
bjp-22865	261	19	of	of	ADP
bjp-22865	261	20	the	the	DET
bjp-22865	261	21	onset	onset	NOUN
bjp-22865	261	22	and	and	CCONJ
bjp-22865	261	23	progression	progression	NOUN
bjp-22865	261	24	of	of	ADP
bjp-22865	261	25	collagen‑induced	collagen‑induce	VERB
bjp-22865	261	26	arthritis	arthritis	NOUN
bjp-22865	261	27	in	in	ADP
bjp-22865	261	28	rats	rat	NOUN
bjp-22865	261	29	by	by	ADP
bjp-22865	261	30	the	the	DET
bjp-22865	261	31	potent	potent	ADJ
bjp-22865	261	32	p38	p38	ADJ
bjp-22865	261	33	mitogen‑acti	mitogen‑acti	NUM
bjp-22865	261	34	-	-	PUNCT
bjp-22865	261	35	vated	vate	VERB
bjp-22865	261	36	protein	protein	NOUN
bjp-22865	261	37	kinase	kinase	PROPN
bjp-22865	261	38	inhibitor	inhibitor	PROPN
bjp-22865	261	39	fr167653	fr167653	PROPN
bjp-22865	261	40	.	.	PUNCT
bjp-22865	262	1	arthritis	arthritis	NOUN
bjp-22865	262	2	rheum	rheum	NOUN
bjp-22865	262	3	.	.	PUNCT
bjp-22865	263	1	2003	2003	NUM
bjp-22865	263	2	;	;	PUNCT
bjp-22865	263	3	48	48	NUM
bjp-22865	263	4	:	:	SYM
bjp-22865	263	5	2670‑81	2670‑81	NUM
bjp-22865	263	6	.	.	X
bjp-22865	263	7	ogata	ogata	PROPN
bjp-22865	263	8	y	y	PROPN
bjp-22865	263	9	,	,	PUNCT
bjp-22865	263	10	enghild	enghild	PROPN
bjp-22865	263	11	jj	jj	PROPN
bjp-22865	263	12	,	,	PUNCT
bjp-22865	263	13	nagase	nagase	PROPN
bjp-22865	263	14	h.	h.	PROPN
bjp-22865	263	15	matrix	matrix	PROPN
bjp-22865	263	16	metalloproteinase	metalloproteinase	PROPN
bjp-22865	263	17	3	3	NUM
bjp-22865	263	18	(	(	PUNCT
bjp-22865	263	19	stromelysin	stromelysin	PROPN
bjp-22865	263	20	)	)	PUNCT
bjp-22865	263	21	activates	activate	VERB
bjp-22865	263	22	the	the	DET
bjp-22865	263	23	precursor	precursor	NOUN
bjp-22865	263	24	for	for	ADP
bjp-22865	263	25	the	the	DET
bjp-22865	263	26	human	human	ADJ
bjp-22865	263	27	matrix	matrix	NOUN
bjp-22865	263	28	metalloproteinase	metalloproteinase	NOUN
bjp-22865	263	29	9	9	NUM
bjp-22865	263	30	.	.	PUNCT
bjp-22865	263	31	j	j	PROPN
bjp-22865	263	32	biol	biol	PROPN
bjp-22865	263	33	chem	chem	NOUN
bjp-22865	263	34	.	.	PUNCT
bjp-22865	264	1	1992	1992	NUM
bjp-22865	264	2	;	;	PUNCT
bjp-22865	264	3	267	267	NUM
bjp-22865	264	4	:	:	PUNCT
bjp-22865	264	5	3581	3581	NUM
bjp-22865	264	6	-	-	SYM
bjp-22865	264	7	84	84	NUM
bjp-22865	264	8	.	.	PUNCT
bjp-22865	265	1	periyasamy	periyasamy	PROPN
bjp-22865	265	2	k	k	NOUN
bjp-22865	265	3	,	,	PUNCT
bjp-22865	265	4	baskaran	baskaran	ADV
bjp-22865	265	5	k	k	NOUN
bjp-22865	265	6	,	,	PUNCT
bjp-22865	265	7	ilakkia	ilakkia	NOUN
bjp-22865	265	8	a	a	PRON
bjp-22865	265	9	,	,	PUNCT
bjp-22865	265	10	vanitha	vanitha	INTJ
bjp-22865	265	11	k	k	NOUN
bjp-22865	265	12	,	,	PUNCT
bjp-22865	265	13	selvaraj	selvaraj	PROPN
bjp-22865	265	14	s	s	PROPN
bjp-22865	265	15	,	,	PUNCT
bjp-22865	265	16	sakthisekaran	sakthisekaran	PROPN
bjp-22865	265	17	d.	d.	PROPN
bjp-22865	265	18	antitumor	antitumor	PROPN
bjp-22865	265	19	efficacy	efficacy	PROPN
bjp-22865	265	20	of	of	ADP
bjp-22865	265	21	tangeretin	tangeretin	NOUN
bjp-22865	265	22	by	by	ADP
bjp-22865	265	23	targeting	target	VERB
bjp-22865	265	24	the	the	DET
bjp-22865	265	25	oxidative	oxidative	ADJ
bjp-22865	265	26	stress	stress	NOUN
bjp-22865	265	27	mediated	mediate	VERB
bjp-22865	265	28	on	on	ADP
bjp-22865	265	29	7,12dimethylbenz(a	7,12dimethylbenz(a	NOUN
bjp-22865	265	30	)	)	PUNCT
bjp-22865	265	31	anthracene	anthracene	NOUN
bjp-22865	265	32	-	-	PUNCT
bjp-22865	265	33	induced	induce	VERB
bjp-22865	265	34	proliferative	proliferative	ADJ
bjp-22865	265	35	breast	breast	NOUN
bjp-22865	265	36	cancer	cancer	NOUN
bjp-22865	265	37	in	in	ADP
bjp-22865	265	38	sprague	sprague	NOUN
bjp-22865	265	39	-	-	PUNCT
bjp-22865	265	40	dawley	dawley	NOUN
bjp-22865	265	41	rats	rat	NOUN
bjp-22865	265	42	.	.	PUNCT
bjp-22865	266	1	cancer	cancer	NOUN
bjp-22865	266	2	chemother	chemother	PROPN
bjp-22865	266	3	pharmacol	pharmacol	PROPN
bjp-22865	266	4	.	.	PROPN
bjp-22865	267	1	2015	2015	NUM
bjp-22865	267	2	;	;	PUNCT
bjp-22865	267	3	75	75	NUM
bjp-22865	267	4	:	:	PUNCT
bjp-22865	267	5	263	263	NUM
bjp-22865	267	6	-	-	SYM
bjp-22865	267	7	72	72	NUM
bjp-22865	267	8	.	.	PUNCT
bjp-22865	268	1	pope	pope	PROPN
bjp-22865	268	2	rm	rm	PROPN
bjp-22865	268	3	.	.	PUNCT
bjp-22865	268	4	apoptosis	apoptosis	NOUN
bjp-22865	268	5	as	as	ADP
bjp-22865	268	6	a	a	DET
bjp-22865	268	7	therapeutic	therapeutic	ADJ
bjp-22865	268	8	tool	tool	NOUN
bjp-22865	268	9	in	in	ADP
bjp-22865	268	10	rheumatoid	rheumatoid	NOUN
bjp-22865	268	11	arthritis	arthritis	NOUN
bjp-22865	268	12	.	.	PUNCT
bjp-22865	269	1	nat	nat	PROPN
bjp-22865	269	2	rev	rev	PROPN
bjp-22865	269	3	immunol	immunol	NOUN
bjp-22865	269	4	.	.	PUNCT
bjp-22865	270	1	2002	2002	NUM
bjp-22865	270	2	;	;	PUNCT
bjp-22865	270	3	2	2	NUM
bjp-22865	270	4	:	:	SYM
bjp-22865	270	5	527	527	NUM
bjp-22865	270	6	-	-	SYM
bjp-22865	270	7	35	35	NUM
bjp-22865	270	8	.	.	PUNCT
bjp-22865	271	1	pratt	pratt	PROPN
bjp-22865	271	2	ag	ag	PROPN
bjp-22865	271	3	,	,	PUNCT
bjp-22865	271	4	isaacs	isaacs	PROPN
bjp-22865	271	5	jd	jd	PROPN
bjp-22865	271	6	,	,	PUNCT
bjp-22865	271	7	mattey	mattey	PROPN
bjp-22865	271	8	dl	dl	PROPN
bjp-22865	271	9	.	.	PROPN
bjp-22865	271	10	current	current	ADJ
bjp-22865	271	11	concepts	concept	NOUN
bjp-22865	271	12	in	in	ADP
bjp-22865	271	13	the	the	DET
bjp-22865	271	14	pathogenesis	pathogenesis	NOUN
bjp-22865	271	15	of	of	ADP
bjp-22865	271	16	early	early	ADJ
bjp-22865	271	17	rheumatoid	rheumatoid	NOUN
bjp-22865	271	18	arthritis	arthritis	NOUN
bjp-22865	271	19	.	.	PUNCT
bjp-22865	272	1	best	good	ADJ
bjp-22865	272	2	pract	pract	PROPN
bjp-22865	272	3	res	re	NOUN
bjp-22865	272	4	clin	clin	PROPN
bjp-22865	272	5	rheumatol	rheumatol	NOUN
bjp-22865	272	6	.	.	PUNCT
bjp-22865	273	1	2009	2009	NUM
bjp-22865	273	2	;	;	PUNCT
bjp-22865	273	3	23	23	NUM
bjp-22865	273	4	:	:	PUNCT
bjp-22865	273	5	37	37	NUM
bjp-22865	273	6	-	-	SYM
bjp-22865	273	7	48	48	NUM
bjp-22865	273	8	.	.	PUNCT
bjp-22865	274	1	rannou	rannou	PROPN
bjp-22865	274	2	f	f	PROPN
bjp-22865	274	3	,	,	PUNCT
bjp-22865	274	4	francois	francois	PROPN
bjp-22865	274	5	m	m	PROPN
bjp-22865	274	6	,	,	PUNCT
bjp-22865	274	7	corvol	corvol	PROPN
bjp-22865	274	8	mt	mt	PROPN
bjp-22865	274	9	,	,	PUNCT
bjp-22865	274	10	berenbaum	berenbaum	NOUN
bjp-22865	274	11	f.	f.	PROPN
bjp-22865	274	12	cartilage	cartilage	NOUN
bjp-22865	274	13	breakdown	breakdown	NOUN
bjp-22865	274	14	in	in	ADP
bjp-22865	274	15	rheumatoid	rheumatoid	NOUN
bjp-22865	274	16	arthritis	arthritis	NOUN
bjp-22865	274	17	.	.	PUNCT
bjp-22865	275	1	joint	joint	ADJ
bjp-22865	275	2	bone	bone	NOUN
bjp-22865	275	3	spine	spine	NOUN
bjp-22865	275	4	.	.	PUNCT
bjp-22865	276	1	2006	2006	NUM
bjp-22865	276	2	;	;	PUNCT
bjp-22865	276	3	73	73	NUM
bjp-22865	276	4	:	:	SYM
bjp-22865	276	5	29	29	NUM
bjp-22865	276	6	-	-	SYM
bjp-22865	276	7	36	36	NUM
bjp-22865	276	8	.	.	PUNCT
bjp-22865	277	1	schett	schett	PROPN
bjp-22865	277	2	g	g	PROPN
bjp-22865	277	3	,	,	PUNCT
bjp-22865	277	4	tohidast	tohidast	NOUN
bjp-22865	277	5	-	-	PUNCT
bjp-22865	277	6	akrad	akrad	NOUN
bjp-22865	277	7	m	m	PROPN
bjp-22865	277	8	,	,	PUNCT
bjp-22865	277	9	smolen	smolen	VERB
bjp-22865	277	10	js	js	ADV
bjp-22865	277	11	,	,	PUNCT
bjp-22865	277	12	schmid	schmid	PROPN
bjp-22865	277	13	bj	bj	PROPN
bjp-22865	277	14	,	,	PUNCT
bjp-22865	277	15	steiner	steiner	PROPN
bjp-22865	277	16	cw	cw	PROPN
bjp-22865	277	17	,	,	PUNCT
bjp-22865	277	18	bitzan	bitzan	NOUN
bjp-22865	277	19	p	p	NOUN
bjp-22865	277	20	,	,	PUNCT
bjp-22865	277	21	zenz	zenz	PROPN
bjp-22865	277	22	p	p	NOUN
bjp-22865	277	23	,	,	PUNCT
bjp-22865	277	24	redlich	redlich	PROPN
bjp-22865	277	25	k	k	PROPN
bjp-22865	277	26	,	,	PUNCT
bjp-22865	277	27	xu	xu	PROPN
bjp-22865	277	28	q	q	NOUN
bjp-22865	277	29	,	,	PUNCT
bjp-22865	277	30	steiner	steiner	PROPN
bjp-22865	277	31	g.	g.	PROPN
bjp-22865	277	32	activation	activation	NOUN
bjp-22865	277	33	,	,	PUNCT
bjp-22865	277	34	differential	differential	ADJ
bjp-22865	277	35	localization	localization	NOUN
bjp-22865	277	36	,	,	PUNCT
bjp-22865	277	37	and	and	CCONJ
bjp-22865	277	38	regulation	regulation	NOUN
bjp-22865	277	39	of	of	ADP
bjp-22865	277	40	the	the	DET
bjp-22865	277	41	stressactivated	stressactivate	VERB
bjp-22865	277	42	protein	protein	NOUN
bjp-22865	277	43	kinases	kinase	NOUN
bjp-22865	277	44	,	,	PUNCT
bjp-22865	277	45	extracellular	extracellular	ADJ
bjp-22865	277	46	signal	signal	NOUN
bjp-22865	277	47	-	-	PUNCT
bjp-22865	277	48	regulated	regulate	VERB
bjp-22865	277	49	kinase	kinase	NOUN
bjp-22865	277	50	,	,	PUNCT
bjp-22865	277	51	c	c	PROPN
bjp-22865	277	52	-	-	PUNCT
bjp-22865	277	53	jun	jun	PROPN
bjp-22865	277	54	n	n	CCONJ
bjp-22865	277	55	-	-	PUNCT
bjp-22865	277	56	terminal	terminal	ADJ
bjp-22865	277	57	kinase	kinase	NOUN
bjp-22865	277	58	,	,	PUNCT
bjp-22865	277	59	and	and	CCONJ
bjp-22865	277	60	p38	p38	NOUN
bjp-22865	277	61	mitogen	mitogen	NOUN
bjp-22865	277	62	-	-	PUNCT
bjp-22865	277	63	activated	activate	VERB
bjp-22865	277	64	protein	protein	NOUN
bjp-22865	277	65	kinase	kinase	NOUN
bjp-22865	277	66	,	,	PUNCT
bjp-22865	277	67	in	in	ADP
bjp-22865	277	68	synovial	synovial	ADJ
bjp-22865	277	69	tissue	tissue	NOUN
bjp-22865	277	70	and	and	CCONJ
bjp-22865	277	71	cells	cell	NOUN
bjp-22865	277	72	in	in	ADP
bjp-22865	277	73	rheumatoid	rheumatoid	NOUN
bjp-22865	277	74	arthritis	arthritis	NOUN
bjp-22865	277	75	.	.	PUNCT
bjp-22865	278	1	arthritis	arthritis	NOUN
bjp-22865	278	2	rheum	rheum	NOUN
bjp-22865	278	3	.	.	PUNCT
bjp-22865	279	1	2000	2000	NUM
bjp-22865	279	2	;	;	PUNCT
bjp-22865	279	3	43	43	NUM
bjp-22865	279	4	:	:	SYM
bjp-22865	279	5	2501	2501	NUM
bjp-22865	279	6	-	-	SYM
bjp-22865	279	7	12	12	NUM
bjp-22865	279	8	.	.	PUNCT
bjp-22865	280	1	shaulian	shaulian	PROPN
bjp-22865	280	2	e	e	PROPN
bjp-22865	280	3	,	,	PUNCT
bjp-22865	280	4	karin	karin	PROPN
bjp-22865	280	5	m.	m.	PROPN
bjp-22865	280	6	ap-1	ap-1	PUNCT
bjp-22865	280	7	as	as	ADP
bjp-22865	280	8	a	a	DET
bjp-22865	280	9	regulator	regulator	NOUN
bjp-22865	280	10	of	of	ADP
bjp-22865	280	11	cell	cell	NOUN
bjp-22865	280	12	life	life	NOUN
bjp-22865	280	13	and	and	CCONJ
bjp-22865	280	14	death	death	NOUN
bjp-22865	280	15	.	.	PUNCT
bjp-22865	281	1	nat	nat	NOUN
bjp-22865	281	2	cell	cell	NOUN
bjp-22865	281	3	biol	biol	PROPN
bjp-22865	281	4	.	.	PUNCT
bjp-22865	282	1	2002	2002	NUM
bjp-22865	282	2	;	;	PUNCT
bjp-22865	282	3	4	4	NUM
bjp-22865	282	4	:	:	PUNCT
bjp-22865	282	5	e131	e131	NUM
bjp-22865	282	6	-	-	SYM
bjp-22865	282	7	36	36	NUM
bjp-22865	282	8	.	.	PUNCT
bjp-22865	282	9	724	724	NUM
bjp-22865	282	10	bangladesh	bangladesh	NOUN
bjp-22865	282	11	j	j	PROPN
bjp-22865	282	12	pharmacol	pharmacol	PROPN
bjp-22865	282	13	2015	2015	NUM
bjp-22865	282	14	;	;	PUNCT
bjp-22865	282	15	10	10	NUM
bjp-22865	282	16	:	:	PUNCT
bjp-22865	282	17	714	714	NUM
bjp-22865	282	18	-	-	SYM
bjp-22865	282	19	725	725	NUM
bjp-22865	282	20	http://www.ncbi.nlm.nih.gov/pubmed/?term=bennett%20b%5bauthor%5d&cauthor=true&cauthor_uid=11435459	http://www.ncbi.nlm.nih.gov/pubmed/?term=bennett%20b%5bauthor%5d&cauthor=true&cauthor_uid=11435459	X
bjp-22865	283	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=karin%20m%5bauthor%5d&cauthor=true&cauthor_uid=11435459	http://www.ncbi.nlm.nih.gov/pubmed/?term=karin%20m%5bauthor%5d&cauthor=true&cauthor_uid=11435459	PROPN
bjp-22865	284	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=yang%20l%5bauthor%5d&cauthor=true&cauthor_uid=11435459	http://www.ncbi.nlm.nih.gov/pubmed/?term=yang%20l%5bauthor%5d&cauthor=true&cauthor_uid=11435459	PROPN
bjp-22865	284	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=manning%20am%5bauthor%5d&cauthor=true&cauthor_uid=11435459	http://www.ncbi.nlm.nih.gov/pubmed/?term=manning%20am%5bauthor%5d&cauthor=true&cauthor_uid=11435459	NOUN
bjp-22865	284	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=firestein%20gs%5bauthor%5d&cauthor=true&cauthor_uid=11435459	http://www.ncbi.nlm.nih.gov/pubmed/?term=firestein%20gs%5bauthor%5d&cauthor=true&cauthor_uid=11435459	VERB
bjp-22865	284	4	http://www.ncbi.nlm.nih.gov/pubmed/?term=kim%20jr%5bauthor%5d&cauthor=true&cauthor_uid=12660227	http://www.ncbi.nlm.nih.gov/pubmed/?term=kim%20jr%5bauthor%5d&cauthor=true&cauthor_uid=12660227	X
bjp-22865	284	5	http://www.ncbi.nlm.nih.gov/pubmed/?term=hwang%20by%5bauthor%5d&cauthor=true&cauthor_uid=12660227	http://www.ncbi.nlm.nih.gov/pubmed/?term=hwang%20by%5bauthor%5d&cauthor=true&cauthor_uid=12660227	NOUN
bjp-22865	284	6	http://www.ncbi.nlm.nih.gov/pubmed/?term=lee%20hy%5bauthor%5d&cauthor=true&cauthor_uid=12660227	http://www.ncbi.nlm.nih.gov/pubmed/?term=lee%20hy%5bauthor%5d&cauthor=true&cauthor_uid=12660227	NOUN
bjp-22865	285	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=song%20ek%5bauthor%5d&cauthor=true&cauthor_uid=12660227	http://www.ncbi.nlm.nih.gov/pubmed/?term=song%20ek%5bauthor%5d&cauthor=true&cauthor_uid=12660227	VERB
bjp-22865	285	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=song%20ek%5bauthor%5d&cauthor=true&cauthor_uid=12660227	http://www.ncbi.nlm.nih.gov/pubmed/?term=song%20ek%5bauthor%5d&cauthor=true&cauthor_uid=12660227	PROPN
bjp-22865	285	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=yoo%20wh%5bauthor%5d&cauthor=true&cauthor_uid=12660227	http://www.ncbi.nlm.nih.gov/pubmed/?term=yoo%20wh%5bauthor%5d&cauthor=true&cauthor_uid=12660227	ADP
bjp-22865	285	4	http://www.ncbi.nlm.nih.gov/pubmed?term=ho%20sc%5bauthor%5d&cauthor=true&cauthor_uid=24955543	http://www.ncbi.nlm.nih.gov/pubmed?term=ho%20sc%5bauthor%5d&cauthor=true&cauthor_uid=24955543	ADJ
bjp-22865	285	5	http://www.ncbi.nlm.nih.gov/pubmed?term=kuo%20ct%5bauthor%5d&cauthor=true&cauthor_uid=24955543	http://www.ncbi.nlm.nih.gov/pubmed?term=kuo%20ct%5bauthor%5d&cauthor=true&cauthor_uid=24955543	NOUN
bjp-22865	286	1	http://www.ncbi.nlm.nih.gov/pubmed/24955543	http://www.ncbi.nlm.nih.gov/pubmed/24955543	ADP
bjp-22865	286	2	http://www.ncbi.nlm.nih.gov/pubmed/24955543	http://www.ncbi.nlm.nih.gov/pubmed/24955543	NUM
bjp-22865	286	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=yoon%20dh%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=yoon%20dh%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	286	4	http://www.ncbi.nlm.nih.gov/pubmed/?term=chang%20wc%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=chang%20wc%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	286	5	http://www.ncbi.nlm.nih.gov/pubmed/?term=shin%20dj%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=shin%20dj%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	286	6	http://www.ncbi.nlm.nih.gov/pubmed/?term=han%20sk%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=han%20sk%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	286	7	http://www.ncbi.nlm.nih.gov/pubmed/?term=park%20sm%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=park%20sm%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	286	8	http://www.ncbi.nlm.nih.gov/pubmed/?term=park%20jh%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=park%20jh%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	286	9	http://www.ncbi.nlm.nih.gov/pubmed/?term=park%20hi%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=park%20hi%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PROPN
bjp-22865	287	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=sung%20jm%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=sung%20jm%5bauthor%5d&cauthor=true&cauthor_uid=16899239	NOUN
bjp-22865	287	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=jang%20y%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=jang%20y%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PUNCT
bjp-22865	287	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=chung%20n%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=chung%20n%5bauthor%5d&cauthor=true&cauthor_uid=16899239	PUNCT
bjp-22865	287	4	http://www.ncbi.nlm.nih.gov/pubmed/?term=hwang%20kc%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=hwang%20kc%5bauthor%5d&cauthor=true&cauthor_uid=16899239	NOUN
bjp-22865	287	5	http://www.ncbi.nlm.nih.gov/pubmed/?term=kim%20tw%5bauthor%5d&cauthor=true&cauthor_uid=16899239	http://www.ncbi.nlm.nih.gov/pubmed/?term=kim%20tw%5bauthor%5d&cauthor=true&cauthor_uid=16899239	ADJ
bjp-22865	287	6	http://www.ncbi.nlm.nih.gov/pubmed/?term=ma%20j%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=ma%20j%5bauthor%5d&cauthor=true&cauthor_uid=10531073	NOUN
bjp-22865	287	7	http://www.ncbi.nlm.nih.gov/pubmed/?term=ida%20h%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=ida%20h%5bauthor%5d&cauthor=true&cauthor_uid=10531073	PROPN
bjp-22865	287	8	http://www.ncbi.nlm.nih.gov/pubmed/?term=mandelin%20j%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=mandelin%20j%5bauthor%5d&cauthor=true&cauthor_uid=10531073	PROPN
bjp-22865	287	9	http://www.ncbi.nlm.nih.gov/pubmed/?term=kinne%20rw%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=kinne%20rw%5bauthor%5d&cauthor=true&cauthor_uid=10531073	NOUN
bjp-22865	287	10	http://www.ncbi.nlm.nih.gov/pubmed/?term=santavirta%20s%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=santavirta%20s%5bauthor%5d&cauthor=true&cauthor_uid=10531073	NOUN
bjp-22865	287	11	http://www.ncbi.nlm.nih.gov/pubmed/?term=sorsa%20t%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=sorsa%20t%5bauthor%5d&cauthor=true&cauthor_uid=10531073	NUM
bjp-22865	287	12	http://www.ncbi.nlm.nih.gov/pubmed/?term=l%c3%b3pez-ot%c3%adn%20c%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=l%c3%b3pez-ot%c3%adn%20c%5bauthor%5d&cauthor=true&cauthor_uid=10531073	NOUN
bjp-22865	287	13	http://www.ncbi.nlm.nih.gov/pubmed/?term=takagi%20m%5bauthor%5d&cauthor=true&cauthor_uid=10531073	http://www.ncbi.nlm.nih.gov/pubmed/?term=takagi%20m%5bauthor%5d&cauthor=true&cauthor_uid=10531073	NUM
bjp-22865	287	14	http://www.ncbi.nlm.nih.gov/pubmed/?term=dambach%20dm%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=dambach%20dm%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PROPN
bjp-22865	287	15	http://www.ncbi.nlm.nih.gov/pubmed/?term=pattoli%20ma%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=pattoli%20ma%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PROPN
bjp-22865	287	16	http://www.ncbi.nlm.nih.gov/pubmed/?term=pattoli%20ma%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=pattoli%20ma%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PROPN
bjp-22865	287	17	http://www.ncbi.nlm.nih.gov/pubmed/?term=lu%20p%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=lu%20p%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PROPN
bjp-22865	288	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=zhou%20xd%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=zhou%20xd%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PRON
bjp-22865	288	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=qiu%20y%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=qiu%20y%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PROPN
bjp-22865	288	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=zusi%20fc%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=zusi%20fc%5bauthor%5d&cauthor=true&cauthor_uid=13130486	ADJ
bjp-22865	288	4	http://www.ncbi.nlm.nih.gov/pubmed/?term=burke%20jr%5bauthor%5d&cauthor=true&cauthor_uid=13130486	http://www.ncbi.nlm.nih.gov/pubmed/?term=burke%20jr%5bauthor%5d&cauthor=true&cauthor_uid=13130486	PROPN
bjp-22865	288	5	http://www.ncbi.nlm.nih.gov/pubmed/25431347	http://www.ncbi.nlm.nih.gov/pubmed/25431347	PROPN
bjp-22865	288	6	http://www.ncbi.nlm.nih.gov/pubmed/?term=schmid%20bj%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=schmid%20bj%5bauthor%5d&cauthor=true&cauthor_uid=11083274	NOUN
bjp-22865	288	7	http://www.ncbi.nlm.nih.gov/pubmed/?term=steiner%20cw%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=steiner%20cw%5bauthor%5d&cauthor=true&cauthor_uid=11083274	NOUN
bjp-22865	288	8	http://www.ncbi.nlm.nih.gov/pubmed/?term=steiner%20cw%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=steiner%20cw%5bauthor%5d&cauthor=true&cauthor_uid=11083274	NOUN
bjp-22865	288	9	http://www.ncbi.nlm.nih.gov/pubmed/?term=bitzan%20p%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=bitzan%20p%5bauthor%5d&cauthor=true&cauthor_uid=11083274	PROPN
bjp-22865	288	10	http://www.ncbi.nlm.nih.gov/pubmed/?term=zenz%20p%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=zenz%20p%5bauthor%5d&cauthor=true&cauthor_uid=11083274	NUM
bjp-22865	288	11	http://www.ncbi.nlm.nih.gov/pubmed/?term=redlich%20k%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=redlich%20k%5bauthor%5d&cauthor=true&cauthor_uid=11083274	NOUN
bjp-22865	288	12	http://www.ncbi.nlm.nih.gov/pubmed/?term=xu%20q%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=xu%20q%5bauthor%5d&cauthor=true&cauthor_uid=11083274	ADJ
bjp-22865	288	13	http://www.ncbi.nlm.nih.gov/pubmed/?term=steiner%20g%5bauthor%5d&cauthor=true&cauthor_uid=11083274	http://www.ncbi.nlm.nih.gov/pubmed/?term=steiner%20g%5bauthor%5d&cauthor=true&cauthor_uid=11083274	PROPN
bjp-22865	288	14	shu	shu	NOUN
bjp-22865	288	15	z	z	PROPN
bjp-22865	288	16	,	,	PUNCT
bjp-22865	288	17	yang	yang	PROPN
bjp-22865	288	18	b	b	PROPN
bjp-22865	288	19	,	,	PUNCT
bjp-22865	288	20	zhao	zhao	PROPN
bjp-22865	288	21	h	h	PROPN
bjp-22865	288	22	,	,	PUNCT
bjp-22865	288	23	xu	xu	PROPN
bjp-22865	288	24	b	b	PROPN
bjp-22865	288	25	,	,	PUNCT
bjp-22865	288	26	jiao	jiao	PROPN
bjp-22865	288	27	w	w	PROPN
bjp-22865	288	28	,	,	PUNCT
bjp-22865	288	29	wang	wang	PROPN
bjp-22865	288	30	q	q	PROPN
bjp-22865	288	31	,	,	PUNCT
bjp-22865	288	32	wang	wang	PROPN
bjp-22865	288	33	z	z	PROPN
bjp-22865	288	34	,	,	PUNCT
bjp-22865	288	35	kuang	kuang	PROPN
bjp-22865	288	36	h.	h.	PROPN
bjp-22865	288	37	tangeretin	tangeretin	PROPN
bjp-22865	288	38	exerts	exert	VERB
bjp-22865	288	39	anti	anti	ADJ
bjp-22865	288	40	-	-	ADJ
bjp-22865	288	41	neuroinflammatory	neuroinflammatory	ADJ
bjp-22865	288	42	effects	effect	NOUN
bjp-22865	288	43	via	via	ADP
bjp-22865	288	44	nfκb	nfκb	ADJ
bjp-22865	288	45	modulation	modulation	NOUN
bjp-22865	288	46	in	in	ADP
bjp-22865	288	47	lipopolysaccharide	lipopolysaccharide	ADV
bjp-22865	288	48	-	-	PUNCT
bjp-22865	288	49	stimulated	stimulate	VERB
bjp-22865	288	50	microglial	microglial	ADJ
bjp-22865	288	51	cells	cell	NOUN
bjp-22865	288	52	.	.	PUNCT
bjp-22865	289	1	int	int	NOUN
bjp-22865	289	2	immunopharmacol	immunopharmacol	PROPN
bjp-22865	289	3	.	.	PROPN
bjp-22865	289	4	2014	2014	NUM
bjp-22865	289	5	;	;	PUNCT
bjp-22865	289	6	19	19	NUM
bjp-22865	289	7	:	:	SYM
bjp-22865	289	8	275	275	NUM
bjp-22865	289	9	-	-	SYM
bjp-22865	289	10	82	82	NUM
bjp-22865	289	11	.	.	PUNCT
bjp-22865	290	1	smith	smith	PROPN
bjp-22865	290	2	wl	wl	PROPN
bjp-22865	290	3	,	,	PUNCT
bjp-22865	290	4	garavito	garavito	PROPN
bjp-22865	290	5	rm	rm	PROPN
bjp-22865	290	6	,	,	PUNCT
bjp-22865	290	7	dewitt	dewitt	PROPN
bjp-22865	290	8	dl	dl	PROPN
bjp-22865	290	9	.	.	PROPN
bjp-22865	290	10	prostaglandin	prostaglandin	VERB
bjp-22865	290	11	endoperoxide	endoperoxide	ADJ
bjp-22865	290	12	h	h	NOUN
bjp-22865	290	13	synthases	synthase	NOUN
bjp-22865	290	14	(	(	PUNCT
bjp-22865	290	15	cyclooxygenases)-1	cyclooxygenases)-1	PROPN
bjp-22865	290	16	and	and	CCONJ
bjp-22865	290	17	-2	-2	INTJ
bjp-22865	290	18	.	.	PUNCT
bjp-22865	291	1	j	j	PROPN
bjp-22865	291	2	biol	biol	PROPN
bjp-22865	291	3	chem	chem	NOUN
bjp-22865	291	4	.	.	PUNCT
bjp-22865	291	5	1996	1996	NUM
bjp-22865	291	6	;	;	PUNCT
bjp-22865	291	7	271	271	NUM
bjp-22865	291	8	:	:	PUNCT
bjp-22865	291	9	33157	33157	NUM
bjp-22865	291	10	-	-	SYM
bjp-22865	291	11	60	60	NUM
bjp-22865	291	12	.	.	PUNCT
bjp-22865	292	1	su	su	PROPN
bjp-22865	292	2	b	b	PROPN
bjp-22865	292	3	,	,	PUNCT
bjp-22865	292	4	karin	karin	PROPN
bjp-22865	292	5	m.	m.	PROPN
bjp-22865	292	6	mitogen	mitogen	PROPN
bjp-22865	292	7	-	-	PUNCT
bjp-22865	292	8	activated	activate	VERB
bjp-22865	292	9	protein	protein	NOUN
bjp-22865	292	10	kinase	kinase	NOUN
bjp-22865	292	11	cascades	cascade	NOUN
bjp-22865	292	12	and	and	CCONJ
bjp-22865	292	13	regulation	regulation	NOUN
bjp-22865	292	14	of	of	ADP
bjp-22865	292	15	gene	gene	NOUN
bjp-22865	292	16	expression	expression	NOUN
bjp-22865	292	17	.	.	PUNCT
bjp-22865	293	1	curr	curr	PROPN
bjp-22865	293	2	opin	opin	PROPN
bjp-22865	293	3	immunol	immunol	NOUN
bjp-22865	293	4	.	.	PUNCT
bjp-22865	293	5	1996	1996	NUM
bjp-22865	293	6	;	;	PUNCT
bjp-22865	293	7	8	8	NUM
bjp-22865	293	8	:	:	SYM
bjp-22865	293	9	402	402	NUM
bjp-22865	293	10	-	-	SYM
bjp-22865	293	11	11	11	NUM
bjp-22865	293	12	.	.	PUNCT
bjp-22865	294	1	sung	sung	PROPN
bjp-22865	294	2	ms	ms	PROPN
bjp-22865	294	3	,	,	PUNCT
bjp-22865	294	4	lee	lee	PROPN
bjp-22865	294	5	eg	eg	PROPN
bjp-22865	294	6	,	,	PUNCT
bjp-22865	294	7	jeon	jeon	PROPN
bjp-22865	294	8	hs	hs	PROPN
bjp-22865	294	9	,	,	PUNCT
bjp-22865	294	10	chae	chae	PROPN
bjp-22865	294	11	hj	hj	PROPN
bjp-22865	294	12	,	,	PUNCT
bjp-22865	294	13	park	park	NOUN
bjp-22865	294	14	sj	sj	PROPN
bjp-22865	294	15	,	,	PUNCT
bjp-22865	294	16	lee	lee	PROPN
bjp-22865	294	17	yc	yc	PROPN
bjp-22865	294	18	,	,	PUNCT
bjp-22865	294	19	yoo	yoo	PROPN
bjp-22865	294	20	wh	wh	PROPN
bjp-22865	294	21	.	.	PUNCT
bjp-22865	294	22	quercetin	quercetin	PROPN
bjp-22865	294	23	inhibits	inhibit	VERB
bjp-22865	294	24	il-1	il-1	ADP
bjp-22865	294	25	induced	induced	ADJ
bjp-22865	294	26	proliferation	proliferation	NOUN
bjp-22865	294	27	and	and	CCONJ
bjp-22865	294	28	production	production	NOUN
bjp-22865	294	29	of	of	ADP
bjp-22865	294	30	mmps	mmp	NOUN
bjp-22865	294	31	,	,	PUNCT
bjp-22865	294	32	cox-2	cox-2	NOUN
bjp-22865	294	33	and	and	CCONJ
bjp-22865	294	34	pge2	pge2	NOUN
bjp-22865	294	35	by	by	ADP
bjp-22865	294	36	rheumatoid	rheumatoid	NOUN
bjp-22865	294	37	synovial	synovial	ADJ
bjp-22865	294	38	fibroblast	fibroblast	NOUN
bjp-22865	294	39	.	.	PUNCT
bjp-22865	295	1	inflammation	inflammation	NOUN
bjp-22865	295	2	2012	2012	NUM
bjp-22865	295	3	;	;	PUNCT
bjp-22865	295	4	35	35	NUM
bjp-22865	295	5	:	:	PUNCT
bjp-22865	295	6	1585	1585	NUM
bjp-22865	295	7	-	-	SYM
bjp-22865	295	8	94	94	NUM
bjp-22865	295	9	.	.	PUNCT
bjp-22865	296	1	sweeney	sweeney	PROPN
bjp-22865	296	2	se	se	PROPN
bjp-22865	296	3	,	,	PUNCT
bjp-22865	296	4	firestein	firestein	PROPN
bjp-22865	296	5	gs	gs	PROPN
bjp-22865	296	6	.	.	PUNCT
bjp-22865	296	7	signal	signal	PROPN
bjp-22865	296	8	transduction	transduction	NOUN
bjp-22865	296	9	in	in	ADP
bjp-22865	296	10	rheumatoid	rheumatoid	NOUN
bjp-22865	296	11	arthritis	arthritis	NOUN
bjp-22865	296	12	.	.	PUNCT
bjp-22865	297	1	curr	curr	PROPN
bjp-22865	297	2	opin	opin	PROPN
bjp-22865	297	3	rheumatol	rheumatol	NOUN
bjp-22865	297	4	.	.	PUNCT
bjp-22865	298	1	2004	2004	NUM
bjp-22865	298	2	;	;	PUNCT
bjp-22865	298	3	16	16	NUM
bjp-22865	298	4	:	:	SYM
bjp-22865	298	5	231	231	NUM
bjp-22865	298	6	-	-	SYM
bjp-22865	298	7	37	37	NUM
bjp-22865	298	8	.	.	PUNCT
bjp-22865	299	1	tak	tak	NOUN
bjp-22865	299	2	pp	pp	PROPN
bjp-22865	299	3	,	,	PUNCT
bjp-22865	299	4	firestein	firestein	PROPN
bjp-22865	299	5	gs	gs	PROPN
bjp-22865	299	6	.	.	PUNCT
bjp-22865	299	7	nf	nf	PROPN
bjp-22865	299	8	-	-	PUNCT
bjp-22865	299	9	kappab	kappab	NOUN
bjp-22865	299	10	:	:	PUNCT
bjp-22865	299	11	a	a	DET
bjp-22865	299	12	key	key	ADJ
bjp-22865	299	13	role	role	NOUN
bjp-22865	299	14	in	in	ADP
bjp-22865	299	15	inflammatory	inflammatory	ADJ
bjp-22865	299	16	diseases	disease	NOUN
bjp-22865	299	17	.	.	PUNCT
bjp-22865	300	1	j	j	PROPN
bjp-22865	300	2	clin	clin	PROPN
bjp-22865	300	3	invest	invest	PROPN
bjp-22865	300	4	.	.	PUNCT
bjp-22865	301	1	2001	2001	NUM
bjp-22865	301	2	;	;	PUNCT
bjp-22865	301	3	107	107	NUM
bjp-22865	301	4	:	:	PUNCT
bjp-22865	301	5	7	7	NUM
bjp-22865	301	6	-	-	SYM
bjp-22865	301	7	11	11	NUM
bjp-22865	301	8	.	.	PUNCT
bjp-22865	302	1	tanida	tanida	PROPN
bjp-22865	302	2	s	s	PROPN
bjp-22865	302	3	,	,	PUNCT
bjp-22865	302	4	yoshitomi	yoshitomi	NOUN
bjp-22865	302	5	h	h	NOUN
bjp-22865	302	6	,	,	PUNCT
bjp-22865	302	7	nishitani	nishitani	PROPN
bjp-22865	302	8	k	k	PROPN
bjp-22865	302	9	,	,	PUNCT
bjp-22865	302	10	ishikawa	ishikawa	PROPN
bjp-22865	302	11	m	m	PROPN
bjp-22865	302	12	,	,	PUNCT
bjp-22865	302	13	kitaori	kitaori	PROPN
bjp-22865	302	14	t	t	PROPN
bjp-22865	302	15	,	,	PUNCT
bjp-22865	302	16	ito	ito	PROPN
bjp-22865	302	17	h	h	PROPN
bjp-22865	302	18	,	,	PUNCT
bjp-22865	302	19	nakamura	nakamura	PROPN
bjp-22865	302	20	t.	t.	PROPN
bjp-22865	302	21	ccl20	ccl20	PROPN
bjp-22865	302	22	produced	produce	VERB
bjp-22865	302	23	in	in	ADP
bjp-22865	302	24	the	the	DET
bjp-22865	302	25	cytokine	cytokine	ADJ
bjp-22865	302	26	network	network	NOUN
bjp-22865	302	27	of	of	ADP
bjp-22865	302	28	rheumatoid	rheumatoid	NOUN
bjp-22865	302	29	arthritis	arthritis	NOUN
bjp-22865	302	30	recruits	recruit	NOUN
bjp-22865	302	31	ccr6	ccr6	ADJ
bjp-22865	302	32	+	+	CCONJ
bjp-22865	302	33	mononuclear	mononuclear	ADJ
bjp-22865	302	34	cells	cell	NOUN
bjp-22865	302	35	and	and	CCONJ
bjp-22865	302	36	enhances	enhance	VERB
bjp-22865	302	37	the	the	DET
bjp-22865	302	38	production	production	NOUN
bjp-22865	302	39	of	of	ADP
bjp-22865	302	40	il-6	il-6	NUM
bjp-22865	302	41	.	.	PUNCT
bjp-22865	303	1	cytokine	cytokine	VERB
bjp-22865	303	2	2009	2009	NUM
bjp-22865	303	3	;	;	PUNCT
bjp-22865	303	4	47	47	NUM
bjp-22865	303	5	:	:	SYM
bjp-22865	303	6	11218	11218	NUM
bjp-22865	303	7	.	.	PUNCT
bjp-22865	304	1	tas	tas	PROPN
bjp-22865	304	2	sw	sw	PROPN
bjp-22865	304	3	,	,	PUNCT
bjp-22865	304	4	remans	reman	NOUN
bjp-22865	304	5	ph	ph	VERB
bjp-22865	304	6	,	,	PUNCT
bjp-22865	304	7	reedquist	reedquist	NOUN
bjp-22865	304	8	ka	ka	PROPN
bjp-22865	304	9	,	,	PUNCT
bjp-22865	304	10	tak	tak	NOUN
bjp-22865	304	11	pp	pp	PROPN
bjp-22865	304	12	.	.	PUNCT
bjp-22865	305	1	signal	signal	PROPN
bjp-22865	305	2	transduction	transduction	NOUN
bjp-22865	305	3	pathways	pathway	NOUN
bjp-22865	305	4	and	and	CCONJ
bjp-22865	305	5	transcription	transcription	NOUN
bjp-22865	305	6	factors	factor	NOUN
bjp-22865	305	7	as	as	ADP
bjp-22865	305	8	therapeutic	therapeutic	ADJ
bjp-22865	305	9	targets	target	NOUN
bjp-22865	305	10	in	in	ADP
bjp-22865	305	11	inflammatory	inflammatory	ADJ
bjp-22865	305	12	disease	disease	NOUN
bjp-22865	305	13	:	:	PUNCT
bjp-22865	305	14	towards	towards	ADP
bjp-22865	305	15	innovative	innovative	ADJ
bjp-22865	305	16	antirheumatic	antirheumatic	ADJ
bjp-22865	305	17	therapy	therapy	NOUN
bjp-22865	305	18	.	.	PUNCT
bjp-22865	306	1	curr	curr	PROPN
bjp-22865	306	2	pharma	pharma	PROPN
bjp-22865	306	3	design	design	NOUN
bjp-22865	306	4	2005	2005	NUM
bjp-22865	306	5	;	;	PUNCT
bjp-22865	306	6	11	11	NUM
bjp-22865	306	7	:	:	PUNCT
bjp-22865	306	8	581	581	NUM
bjp-22865	306	9	-	-	SYM
bjp-22865	306	10	611	611	NUM
bjp-22865	306	11	.	.	PUNCT
bjp-22865	307	1	tolboom	tolboom	NOUN
bjp-22865	307	2	tc	tc	NOUN
bjp-22865	307	3	,	,	PUNCT
bjp-22865	307	4	pieterman	pieterman	NOUN
bjp-22865	307	5	e	e	NOUN
bjp-22865	307	6	,	,	PUNCT
bjp-22865	307	7	van	van	PROPN
bjp-22865	307	8	der	der	NOUN
bjp-22865	307	9	laan	laan	PROPN
bjp-22865	307	10	wh	wh	PROPN
bjp-22865	307	11	,	,	PUNCT
bjp-22865	307	12	toes	toe	NOUN
bjp-22865	307	13	re	re	VERB
bjp-22865	307	14	,	,	PUNCT
bjp-22865	307	15	huidekoper	huidekoper	PROPN
bjp-22865	307	16	al	al	PROPN
bjp-22865	307	17	,	,	PUNCT
bjp-22865	307	18	nelissen	nelissen	PROPN
bjp-22865	307	19	rg	rg	PROPN
bjp-22865	307	20	,	,	PUNCT
bjp-22865	307	21	breedveld	breedveld	VERB
bjp-22865	307	22	fc	fc	PROPN
bjp-22865	307	23	,	,	PUNCT
bjp-22865	307	24	huizinga	huizinga	PROPN
bjp-22865	307	25	tw	tw	INTJ
bjp-22865	307	26	.	.	PUNCT
bjp-22865	308	1	invasive	invasive	ADJ
bjp-22865	308	2	properties	property	NOUN
bjp-22865	308	3	of	of	ADP
bjp-22865	308	4	fibroblast	fibroblast	ADJ
bjp-22865	308	5	-	-	PUNCT
bjp-22865	308	6	like	like	ADJ
bjp-22865	308	7	synoviocytes	synoviocyte	NOUN
bjp-22865	308	8	:	:	PUNCT
bjp-22865	308	9	correlation	correlation	NOUN
bjp-22865	308	10	with	with	ADP
bjp-22865	308	11	growth	growth	NOUN
bjp-22865	308	12	characteristics	characteristic	NOUN
bjp-22865	308	13	and	and	CCONJ
bjp-22865	308	14	expression	expression	NOUN
bjp-22865	308	15	of	of	ADP
bjp-22865	308	16	mmp-1	mmp-1	NOUN
bjp-22865	308	17	,	,	PUNCT
bjp-22865	308	18	mmp-3	mmp-3	NOUN
bjp-22865	308	19	,	,	PUNCT
bjp-22865	308	20	and	and	CCONJ
bjp-22865	308	21	mmp-10	mmp-10	PROPN
bjp-22865	308	22	.	.	PROPN
bjp-22865	308	23	annals	annals	PROPN
bjp-22865	308	24	rheum	rheum	PROPN
bjp-22865	308	25	dis	dis	PROPN
bjp-22865	308	26	.	.	PUNCT
bjp-22865	309	1	2002	2002	NUM
bjp-22865	309	2	;	;	PUNCT
bjp-22865	309	3	61	61	NUM
bjp-22865	309	4	:	:	SYM
bjp-22865	309	5	975	975	NUM
bjp-22865	309	6	-	-	SYM
bjp-22865	309	7	80	80	NUM
bjp-22865	309	8	.	.	PUNCT
bjp-22865	310	1	williams	williams	PROPN
bjp-22865	310	2	ro	ro	PROPN
bjp-22865	310	3	,	,	PUNCT
bjp-22865	310	4	paleolog	paleolog	NOUN
bjp-22865	310	5	e	e	NOUN
bjp-22865	310	6	,	,	PUNCT
bjp-22865	310	7	feldmann	feldmann	NOUN
bjp-22865	310	8	m.	m.	NOUN
bjp-22865	310	9	cytokine	cytokine	NOUN
bjp-22865	310	10	inhibitors	inhibitor	NOUN
bjp-22865	310	11	in	in	ADP
bjp-22865	310	12	rheumatoid	rheumatoid	NOUN
bjp-22865	310	13	arthritis	arthritis	NOUN
bjp-22865	310	14	and	and	CCONJ
bjp-22865	310	15	other	other	ADJ
bjp-22865	310	16	autoimmune	autoimmune	ADJ
bjp-22865	310	17	diseases	disease	NOUN
bjp-22865	310	18	.	.	PUNCT
bjp-22865	311	1	curr	curr	PROPN
bjp-22865	311	2	opin	opin	PROPN
bjp-22865	311	3	pharmacol	pharmacol	PROPN
bjp-22865	311	4	.	.	PUNCT
bjp-22865	312	1	2007	2007	NUM
bjp-22865	312	2	;	;	PUNCT
bjp-22865	312	3	7	7	NUM
bjp-22865	312	4	:	:	SYM
bjp-22865	312	5	412	412	NUM
bjp-22865	312	6	-	-	SYM
bjp-22865	312	7	17	17	NUM
bjp-22865	312	8	.	.	PUNCT
bjp-22865	313	1	yang	yang	PROPN
bjp-22865	313	2	cm	cm	PROPN
bjp-22865	313	3	,	,	PUNCT
bjp-22865	313	4	luo	luo	PROPN
bjp-22865	313	5	sf	sf	PROPN
bjp-22865	313	6	,	,	PUNCT
bjp-22865	313	7	hsieh	hsieh	PROPN
bjp-22865	313	8	hl	hl	NOUN
bjp-22865	313	9	,	,	PUNCT
bjp-22865	313	10	chi	chi	PROPN
bjp-22865	313	11	pl	pl	PROPN
bjp-22865	313	12	,	,	PUNCT
bjp-22865	313	13	lin	lin	PROPN
bjp-22865	313	14	cc	cc	PROPN
bjp-22865	313	15	,	,	PUNCT
bjp-22865	313	16	wu	wu	PROPN
bjp-22865	313	17	cc	cc	PROPN
bjp-22865	313	18	,	,	PUNCT
bjp-22865	313	19	hsiao	hsiao	PROPN
bjp-22865	313	20	ld	ld	PROPN
bjp-22865	313	21	.	.	PROPN
bjp-22865	314	1	interleukin-1	interleukin-1	NOUN
bjp-22865	314	2	beta	beta	NOUN
bjp-22865	314	3	induces	induce	VERB
bjp-22865	314	4	icam-1	icam-1	NUM
bjp-22865	314	5	expression	expression	NOUN
bjp-22865	314	6	enhancing	enhance	VERB
bjp-22865	314	7	leukocyte	leukocyte	NOUN
bjp-22865	314	8	adhesion	adhesion	NOUN
bjp-22865	314	9	in	in	ADP
bjp-22865	314	10	human	human	ADJ
bjp-22865	314	11	rheumatoid	rheumatoid	NOUN
bjp-22865	314	12	arthritis	arthritis	NOUN
bjp-22865	314	13	synovial	synovial	ADJ
bjp-22865	314	14	fibroblasts	fibroblast	NOUN
bjp-22865	314	15	:	:	PUNCT
bjp-22865	314	16	involvement	involvement	NOUN
bjp-22865	314	17	of	of	ADP
bjp-22865	314	18	erk	erk	PROPN
bjp-22865	314	19	,	,	PUNCT
bjp-22865	314	20	jnk	jnk	PROPN
bjp-22865	314	21	,	,	PUNCT
bjp-22865	314	22	ap-1	ap-1	ADV
bjp-22865	314	23	,	,	PUNCT
bjp-22865	314	24	and	and	CCONJ
bjp-22865	314	25	nf	nf	PROPN
bjp-22865	314	26	kappa	kappa	PROPN
bjp-22865	314	27	b.	b.	PROPN
bjp-22865	314	28	j	j	PROPN
bjp-22865	314	29	cell	cell	PROPN
bjp-22865	314	30	physiol	physiol	PROPN
bjp-22865	314	31	.	.	PUNCT
bjp-22865	315	1	2010	2010	NUM
bjp-22865	315	2	;	;	PUNCT
bjp-22865	315	3	224	224	NUM
bjp-22865	315	4	:	:	PUNCT
bjp-22865	315	5	516	516	NUM
bjp-22865	315	6	-	-	SYM
bjp-22865	315	7	26	26	NUM
bjp-22865	315	8	.	.	PUNCT
bjp-22865	316	1	bangladesh	bangladesh	PROPN
bjp-22865	316	2	j	j	PROPN
bjp-22865	316	3	pharmacol	pharmacol	PROPN
bjp-22865	316	4	2015	2015	NUM
bjp-22865	316	5	;	;	PUNCT
bjp-22865	316	6	10	10	NUM
bjp-22865	316	7	:	:	PUNCT
bjp-22865	316	8	714	714	NUM
bjp-22865	316	9	-	-	SYM
bjp-22865	316	10	725	725	NUM
bjp-22865	316	11	725	725	NUM
bjp-22865	316	12	http://www.ncbi.nlm.nih.gov/pubmed/24462494	http://www.ncbi.nlm.nih.gov/pubmed/24462494	NUM
bjp-22865	316	13	http://www.ncbi.nlm.nih.gov/pubmed/?term=quercetin+inhibits+il-1%ce%b2-induced+proliferation+and+productionof+mmps%2c+cox-2%2c+and+pge2+by+rheumatoid+synovial+fibroblast	http://www.ncbi.nlm.nih.gov/pubmed/?term=quercetin+inhibits+il-1%ce%b2-induced+proliferation+and+productionof+mmps%2c+cox-2%2c+and+pge2+by+rheumatoid+synovial+fibroblast	NOUN
bjp-22865	316	14	article	article	NOUN
bjp-22865	316	15	info	info	NOUN
bjp-22865	316	16	:	:	PUNCT
bjp-22865	316	17	abstract	abstract	ADJ
bjp-22865	316	18	:	:	PUNCT
bjp-22865	316	19	introduction	introduction	NOUN
bjp-22865	316	20	:	:	PUNCT
bjp-22865	316	21	dateprinted	dateprinte	VERB
bjp-22865	316	22	:	:	PUNCT
bjp-22865	316	23	this	this	DET
bjp-22865	316	24	article	article	NOUN
bjp-22865	316	25	was	be	AUX
bjp-22865	316	26	downloaded	download	VERB
bjp-22865	316	27	by	by	ADP
bjp-22865	316	28	you	you	PRON
bjp-22865	316	29	on	on	ADP
bjp-22865	316	30	:	:	PUNCT
bjp-22865	316	31	aug	aug	PROPN
bjp-22865	316	32	21	21	NUM
bjp-22865	316	33	,	,	PUNCT
bjp-22865	316	34	2015	2015	NUM