id	sid	tid	token	lemma	pos
bjp-23039	1	1	bangladesh	bangladesh	PROPN
bjp-23039	1	2	journal	journal	PROPN
bjp-23039	1	3	of	of	ADP
bjp-23039	1	4	pharmacology	pharmacology	NOUN
bjp-23039	1	5	research	research	NOUN
bjp-23039	1	6	article	article	NOUN
bjp-23039	1	7	fisetin	fisetin	NOUN
bjp-23039	1	8	,	,	PUNCT
bjp-23039	1	9	a	a	DET
bjp-23039	1	10	dietary	dietary	ADJ
bjp-23039	1	11	flavonoid	flavonoid	NOUN
bjp-23039	1	12	induces	induce	VERB
bjp-23039	1	13	apoptosis	apoptosis	NOUN
bjp-23039	1	14	via	via	ADP
bjp-23039	1	15	modulating	modulate	VERB
bjp-23039	1	16	the	the	DET
bjp-23039	1	17	mapk	mapk	NOUN
bjp-23039	1	18	and	and	CCONJ
bjp-23039	1	19	pi3k	pi3k	PROPN
bjp-23039	1	20	/	/	SYM
bjp-23039	1	21	akt	akt	PROPN
bjp-23039	1	22	signalling	signal	VERB
bjp-23039	1	23	pathways	pathway	NOUN
bjp-23039	1	24	in	in	ADP
bjp-23039	1	25	human	human	ADJ
bjp-23039	1	26	osteosarcoma	osteosarcoma	X
bjp-23039	1	27	(	(	PUNCT
bjp-23039	1	28	u-2	u-2	PROPN
bjp-23039	1	29	os	os	NOUN
bjp-23039	1	30	)	)	PUNCT
bjp-23039	1	31	cells	cell	NOUN
bjp-23039	1	32	bjp	bjp	NOUN
bjp-23039	1	33	introduction	introduction	NOUN
bjp-23039	1	34	osteosarcoma	osteosarcoma	VERB
bjp-23039	1	35	,	,	PUNCT
bjp-23039	1	36	most	most	ADV
bjp-23039	1	37	frequent	frequent	ADJ
bjp-23039	1	38	of	of	ADP
bjp-23039	1	39	the	the	DET
bjp-23039	1	40	bone	bone	NOUN
bjp-23039	1	41	tumors	tumor	NOUN
bjp-23039	1	42	,	,	PUNCT
bjp-23039	1	43	occurs	occur	VERB
bjp-23039	1	44	predominantly	predominantly	ADV
bjp-23039	1	45	in	in	ADP
bjp-23039	1	46	adolescents	adolescent	NOUN
bjp-23039	1	47	and	and	CCONJ
bjp-23039	1	48	children	child	NOUN
bjp-23039	1	49	.	.	PUNCT
bjp-23039	2	1	it	it	PRON
bjp-23039	2	2	is	be	AUX
bjp-23039	2	3	characterized	characterize	VERB
bjp-23039	2	4	by	by	ADP
bjp-23039	2	5	high	high	ADJ
bjp-23039	2	6	recurrence	recurrence	NOUN
bjp-23039	2	7	and	and	CCONJ
bjp-23039	2	8	metastasis	metastasis	NOUN
bjp-23039	2	9	of	of	ADP
bjp-23039	2	10	bone	bone	NOUN
bjp-23039	2	11	and	and	CCONJ
bjp-23039	2	12	soft	soft	ADJ
bjp-23039	2	13	tissue	tissue	NOUN
bjp-23039	2	14	(	(	PUNCT
bjp-23039	2	15	kager	kager	NOUN
bjp-23039	2	16	et	et	PROPN
bjp-23039	2	17	al	al	PROPN
bjp-23039	2	18	.	.	PROPN
bjp-23039	2	19	,	,	PUNCT
bjp-23039	2	20	2003	2003	NUM
bjp-23039	2	21	;	;	PUNCT
bjp-23039	2	22	kim	kim	PROPN
bjp-23039	2	23	et	et	PROPN
bjp-23039	2	24	al	al	PROPN
bjp-23039	2	25	.	.	PROPN
bjp-23039	2	26	,	,	PUNCT
bjp-23039	2	27	2004	2004	NUM
bjp-23039	2	28	)	)	PUNCT
bjp-23039	2	29	.	.	PUNCT
bjp-23039	3	1	treatment	treatment	NOUN
bjp-23039	3	2	includes	include	VERB
bjp-23039	3	3	multimodal	multimodal	NOUN
bjp-23039	3	4	approaches	approach	NOUN
bjp-23039	3	5	including	include	VERB
bjp-23039	3	6	surgery	surgery	NOUN
bjp-23039	3	7	,	,	PUNCT
bjp-23039	3	8	radiotherapy	radiotherapy	NOUN
bjp-23039	3	9	and	and	CCONJ
bjp-23039	3	10	chemotherapy	chemotherapy	NOUN
bjp-23039	3	11	(	(	PUNCT
bjp-23039	3	12	guijarro	guijarro	VERB
bjp-23039	3	13	et	et	PROPN
bjp-23039	3	14	al	al	PROPN
bjp-23039	3	15	.	.	PROPN
bjp-23039	3	16	,	,	PUNCT
bjp-23039	3	17	2014	2014	NUM
bjp-23039	3	18	;	;	PUNCT
bjp-23039	3	19	luetke	luetke	NOUN
bjp-23039	3	20	et	et	PROPN
bjp-23039	3	21	al	al	PROPN
bjp-23039	3	22	.	.	PROPN
bjp-23039	3	23	,	,	PUNCT
bjp-23039	3	24	2014	2014	NUM
bjp-23039	3	25	)	)	PUNCT
bjp-23039	3	26	.	.	PUNCT
bjp-23039	4	1	however	however	ADV
bjp-23039	4	2	,	,	PUNCT
bjp-23039	4	3	drug	drug	NOUN
bjp-23039	4	4	resistance	resistance	NOUN
bjp-23039	4	5	and	and	CCONJ
bjp-23039	4	6	severe	severe	ADJ
bjp-23039	4	7	side	side	NOUN
bjp-23039	4	8	effects	effect	NOUN
bjp-23039	4	9	associated	associate	VERB
bjp-23039	4	10	with	with	ADP
bjp-23039	4	11	conventional	conventional	ADJ
bjp-23039	4	12	therapeutics	therapeutic	NOUN
bjp-23039	4	13	(	(	PUNCT
bjp-23039	4	14	chou	chou	NOUN
bjp-23039	4	15	and	and	CCONJ
bjp-23039	4	16	gorlick	gorlick	PROPN
bjp-23039	4	17	,	,	PUNCT
bjp-23039	4	18	2006	2006	NUM
bjp-23039	4	19	)	)	PUNCT
bjp-23039	4	20	have	have	AUX
bjp-23039	4	21	urged	urge	VERB
bjp-23039	4	22	for	for	ADP
bjp-23039	4	23	novel	novel	ADJ
bjp-23039	4	24	and	and	CCONJ
bjp-23039	4	25	more	more	ADV
bjp-23039	4	26	effective	effective	ADJ
bjp-23039	4	27	therapeutics	therapeutic	NOUN
bjp-23039	4	28	.	.	PUNCT
bjp-23039	5	1	studies	study	NOUN
bjp-23039	5	2	have	have	AUX
bjp-23039	5	3	reported	report	VERB
bjp-23039	5	4	dysregulation	dysregulation	NOUN
bjp-23039	5	5	of	of	ADP
bjp-23039	5	6	several	several	ADJ
bjp-23039	5	7	signalling	signal	VERB
bjp-23039	5	8	pathways	pathway	NOUN
bjp-23039	5	9	such	such	ADJ
bjp-23039	5	10	as	as	ADP
bjp-23039	5	11	phosphatidylinositol	phosphatidylinositol	NOUN
bjp-23039	5	12	3kinase	3kinase	NUM
bjp-23039	5	13	(	(	PUNCT
bjp-23039	5	14	pi3k)/akt	pi3k)/akt	PROPN
bjp-23039	5	15	pathway	pathway	NOUN
bjp-23039	5	16	(	(	PUNCT
bjp-23039	5	17	zhang	zhang	PROPN
bjp-23039	5	18	et	et	PROPN
bjp-23039	5	19	al	al	PROPN
bjp-23039	5	20	.	.	PROPN
bjp-23039	5	21	,	,	PUNCT
bjp-23039	5	22	2015	2015	NUM
bjp-23039	5	23	)	)	PUNCT
bjp-23039	5	24	.	.	PUNCT
bjp-23039	6	1	pi3k/	pi3k/	PROPN
bjp-23039	6	2	akt	akt	PROPN
bjp-23039	6	3	pathway	pathway	NOUN
bjp-23039	6	4	is	be	AUX
bjp-23039	6	5	negatively	negatively	ADV
bjp-23039	6	6	regulated	regulate	VERB
bjp-23039	6	7	by	by	ADP
bjp-23039	6	8	phosphatase	phosphatase	NOUN
bjp-23039	6	9	and	and	CCONJ
bjp-23039	6	10	tensin	tensin	PROPN
bjp-23039	6	11	homolog	homolog	PROPN
bjp-23039	6	12	(	(	PUNCT
bjp-23039	6	13	pten	pten	NOUN
bjp-23039	6	14	)	)	PUNCT
bjp-23039	6	15	can	can	AUX
bjp-23039	6	16	activate	activate	VERB
bjp-23039	6	17	downstream	downstream	ADJ
bjp-23039	6	18	targets	target	NOUN
bjp-23039	6	19	such	such	ADJ
bjp-23039	6	20	as	as	ADP
bjp-23039	6	21	mammalian	mammalian	ADJ
bjp-23039	6	22	target	target	NOUN
bjp-23039	6	23	of	of	ADP
bjp-23039	6	24	rapamycin	rapamycin	NOUN
bjp-23039	6	25	(	(	PUNCT
bjp-23039	6	26	mtor	mtor	PROPN
bjp-23039	6	27	)	)	PUNCT
bjp-23039	7	1	(	(	PUNCT
bjp-23039	7	2	zhang	zhang	X
bjp-23039	7	3	et	et	PROPN
bjp-23039	7	4	al	al	PROPN
bjp-23039	7	5	.	.	PROPN
bjp-23039	7	6	,	,	PUNCT
bjp-23039	7	7	2015	2015	NUM
bjp-23039	7	8	)	)	PUNCT
bjp-23039	7	9	.	.	PUNCT
bjp-23039	8	1	as	as	ADP
bjp-23039	8	2	a	a	DET
bjp-23039	8	3	vital	vital	ADJ
bjp-23039	8	4	pathway	pathway	NOUN
bjp-23039	8	5	in	in	ADP
bjp-23039	8	6	various	various	ADJ
bjp-23039	8	7	physiological	physiological	ADJ
bjp-23039	8	8	and	and	CCONJ
bjp-23039	8	9	pathological	pathological	ADJ
bjp-23039	8	10	processes	process	NOUN
bjp-23039	8	11	it	it	PRON
bjp-23039	8	12	is	be	AUX
bjp-23039	8	13	well	well	ADV
bjp-23039	8	14	established	establish	VERB
bjp-23039	8	15	in	in	ADP
bjp-23039	8	16	human	human	ADJ
bjp-23039	8	17	cancers	cancer	NOUN
bjp-23039	8	18	(	(	PUNCT
bjp-23039	8	19	yuan	yuan	NOUN
bjp-23039	8	20	and	and	CCONJ
bjp-23039	8	21	cantley	cantley	NOUN
bjp-23039	8	22	,	,	PUNCT
bjp-23039	8	23	2008	2008	NUM
bjp-23039	8	24	;	;	PUNCT
bjp-23039	8	25	porta	porta	PROPN
bjp-23039	8	26	et	et	PROPN
bjp-23039	8	27	al	al	PROPN
bjp-23039	8	28	.	.	PROPN
bjp-23039	8	29	,	,	PUNCT
bjp-23039	8	30	2014	2014	NUM
bjp-23039	8	31	)	)	PUNCT
bjp-23039	8	32	.	.	PUNCT
bjp-23039	9	1	extracellular	extracellular	ADJ
bjp-23039	9	2	signal	signal	NOUN
bjp-23039	9	3	regulated	regulate	VERB
bjp-23039	9	4	kinase	kinase	NOUN
bjp-23039	9	5	(	(	PUNCT
bjp-23039	9	6	erk1/2	erk1/2	PROPN
bjp-23039	9	7	)	)	PUNCT
bjp-23039	9	8	,	,	PUNCT
bjp-23039	9	9	c	c	X
bjp-23039	9	10	-	-	PUNCT
bjp-23039	9	11	jun	jun	PROPN
bjp-23039	9	12	n	n	CCONJ
bjp-23039	9	13	-terminal	-terminal	PROPN
bjp-23039	9	14	(	(	PUNCT
bjp-23039	9	15	jnk	jnk	PROPN
bjp-23039	9	16	)	)	PUNCT
bjp-23039	9	17	and	and	CCONJ
bjp-23039	9	18	p38	p38	NOUN
bjp-23039	9	19	mapk	mapk	NOUN
bjp-23039	9	20	,	,	PUNCT
bjp-23039	9	21	main	main	ADJ
bjp-23039	9	22	members	member	NOUN
bjp-23039	9	23	of	of	ADP
bjp-23039	9	24	the	the	DET
bjp-23039	9	25	mitogen	mitogen	NOUN
bjp-23039	9	26	-	-	PUNCT
bjp-23039	9	27	activated	activate	VERB
bjp-23039	9	28	protein	protein	NOUN
bjp-23039	9	29	kinases	kinase	NOUN
bjp-23039	9	30	(	(	PUNCT
bjp-23039	9	31	mapks	mapks	NOUN
bjp-23039	9	32	)	)	PUNCT
bjp-23039	9	33	family	family	NOUN
bjp-23039	9	34	regulate	regulate	VERB
bjp-23039	9	35	several	several	ADJ
bjp-23039	9	36	of	of	ADP
bjp-23039	9	37	cellular	cellular	ADJ
bjp-23039	9	38	responses	response	NOUN
bjp-23039	9	39	(	(	PUNCT
bjp-23039	9	40	genestra	genestra	NOUN
bjp-23039	9	41	,	,	PUNCT
bjp-23039	9	42	2007	2007	NUM
bjp-23039	9	43	;	;	PUNCT
bjp-23039	9	44	wagner	wagner	NOUN
bjp-23039	9	45	and	and	CCONJ
bjp-23039	9	46	nebreda	nebreda	PROPN
bjp-23039	9	47	,	,	PUNCT
bjp-23039	9	48	2009	2009	NUM
bjp-23039	9	49	)	)	PUNCT
bjp-23039	9	50	.	.	PUNCT
bjp-23039	10	1	mapk	mapk	NOUN
bjp-23039	10	2	cascades	cascade	NOUN
bjp-23039	10	3	exert	exert	VERB
bjp-23039	10	4	crucial	crucial	ADJ
bjp-23039	10	5	roles	role	NOUN
bjp-23039	10	6	in	in	ADP
bjp-23039	10	7	drug	drug	NOUN
bjp-23039	10	8	-	-	PUNCT
bjp-23039	10	9	induced	induce	VERB
bjp-23039	10	10	apoptosis	apoptosis	NOUN
bjp-23039	10	11	in	in	ADP
bjp-23039	10	12	osteosarcoma	osteosarcoma	ADJ
bjp-23039	10	13	(	(	PUNCT
bjp-23039	10	14	chen	chen	PROPN
bjp-23039	10	15	et	et	PROPN
bjp-23039	10	16	al	al	PROPN
bjp-23039	10	17	.	.	PROPN
bjp-23039	10	18	,	,	PUNCT
bjp-23039	10	19	2009	2009	NUM
bjp-23039	10	20	;	;	PUNCT
bjp-23039	10	21	noh	noh	PROPN
bjp-23039	10	22	et	et	PROPN
bjp-23039	10	23	al	al	PROPN
bjp-23039	10	24	.	.	PROPN
bjp-23039	10	25	,	,	PUNCT
bjp-23039	10	26	2011	2011	NUM
bjp-23039	10	27	)	)	PUNCT
bjp-23039	10	28	.	.	PUNCT
bjp-23039	11	1	evidences	evidence	NOUN
bjp-23039	11	2	suggest	suggest	VERB
bjp-23039	11	3	that	that	SCONJ
bjp-23039	11	4	cancer	cancer	NOUN
bjp-23039	11	5	cells	cell	NOUN
bjp-23039	11	6	are	be	AUX
bjp-23039	11	7	under	under	ADP
bjp-23039	11	8	increased	increase	VERB
bjp-23039	11	9	oxidative	oxidative	ADJ
bjp-23039	11	10	stress	stress	NOUN
bjp-23039	11	11	(	(	PUNCT
bjp-23039	11	12	pelicano	pelicano	PROPN
bjp-23039	11	13	et	et	PROPN
bjp-23039	11	14	al	al	PROPN
bjp-23039	11	15	.	.	PROPN
bjp-23039	11	16	,	,	PUNCT
bjp-23039	11	17	2004	2004	NUM
bjp-23039	11	18	)	)	PUNCT
bjp-23039	11	19	.	.	PUNCT
bjp-23039	12	1	further	further	PROPN
bjp-23039	12	2	excessive	excessive	ADJ
bjp-23039	12	3	reactive	reactive	ADJ
bjp-23039	12	4	oxygen	oxygen	NOUN
bjp-23039	12	5	species	specie	NOUN
bjp-23039	12	6	(	(	PUNCT
bjp-23039	12	7	ros	ros	PROPN
bjp-23039	12	8	)	)	PUNCT
bjp-23039	12	9	affect	affect	VERB
bjp-23039	12	10	mapk	mapk	NOUN
bjp-23039	12	11	signals	signal	NOUN
bjp-23039	12	12	(	(	PUNCT
bjp-23039	12	13	shen	shen	NOUN
bjp-23039	12	14	and	and	CCONJ
bjp-23039	12	15	liu	liu	PROPN
bjp-23039	12	16	,	,	PUNCT
bjp-23039	12	17	2006	2006	NUM
bjp-23039	12	18	;	;	PUNCT
bjp-23039	12	19	avisetti	avisetti	PROPN
bjp-23039	12	20	et	et	PROPN
bjp-23039	12	21	al	al	PROPN
bjp-23039	12	22	.	.	PROPN
bjp-23039	12	23	,	,	PUNCT
bjp-23039	12	24	2014	2014	NUM
bjp-23039	12	25	)	)	PUNCT
bjp-23039	12	26	.	.	PUNCT
bjp-23039	13	1	accordingly	accordingly	ADV
bjp-23039	13	2	,	,	PUNCT
bjp-23039	13	3	targeted	target	VERB
bjp-23039	13	4	inhibition	inhibition	NOUN
bjp-23039	13	5	of	of	ADP
bjp-23039	13	6	the	the	DET
bjp-23039	13	7	mapk	mapk	NOUN
bjp-23039	13	8	and	and	CCONJ
bjp-23039	13	9	pi3	pi3	NOUN
bjp-23039	13	10	/	/	SYM
bjp-23039	13	11	akt	akt	PROPN
bjp-23039	13	12	pathways	pathway	NOUN
bjp-23039	13	13	may	may	AUX
bjp-23039	13	14	be	be	AUX
bjp-23039	13	15	effective	effective	ADJ
bjp-23039	13	16	in	in	ADP
bjp-23039	13	17	cancer	cancer	NOUN
bjp-23039	13	18	treatment	treatment	NOUN
bjp-23039	13	19	.	.	PUNCT
bjp-23039	14	1	studies	study	NOUN
bjp-23039	14	2	have	have	AUX
bjp-23039	14	3	demonstrated	demonstrate	VERB
bjp-23039	14	4	anti	anti	ADJ
bjp-23039	14	5	-	-	ADJ
bjp-23039	14	6	cancer	cancer	ADJ
bjp-23039	14	7	effects	effect	NOUN
bjp-23039	14	8	of	of	ADP
bjp-23039	14	9	various	various	ADJ
bjp-23039	14	10	phytochemicals	phytochemical	NOUN
bjp-23039	14	11	(	(	PUNCT
bjp-23039	14	12	lin	lin	PROPN
bjp-23039	14	13	et	et	PROPN
bjp-23039	14	14	al	al	PROPN
bjp-23039	14	15	.	.	PROPN
bjp-23039	14	16	,	,	PUNCT
bjp-23039	14	17	2011	2011	NUM
bjp-23039	14	18	;	;	PUNCT
bjp-23039	14	19	li	li	PROPN
bjp-23039	14	20	et	et	PROPN
bjp-23039	14	21	al	al	PROPN
bjp-23039	14	22	.	.	PROPN
bjp-23039	14	23	,	,	PUNCT
bjp-23039	14	24	2014	2014	NUM
bjp-23039	14	25	,	,	PUNCT
bjp-23039	14	26	a	a	DET
bjp-23039	14	27	journal	journal	NOUN
bjp-23039	14	28	of	of	ADP
bjp-23039	14	29	the	the	DET
bjp-23039	14	30	bangladesh	bangladesh	NOUN
bjp-23039	14	31	pharmacological	pharmacological	ADJ
bjp-23039	14	32	society	society	NOUN
bjp-23039	14	33	(	(	PUNCT
bjp-23039	14	34	bdps	bdps	NOUN
bjp-23039	14	35	)	)	PUNCT
bjp-23039	14	36	bangladesh	bangladesh	PROPN
bjp-23039	14	37	j	j	PROPN
bjp-23039	14	38	pharmacol	pharmacol	PROPN
bjp-23039	14	39	2015	2015	NUM
bjp-23039	14	40	;	;	PUNCT
bjp-23039	14	41	10	10	NUM
bjp-23039	14	42	:	:	SYM
bjp-23039	14	43	820	820	NUM
bjp-23039	14	44	-	-	SYM
bjp-23039	14	45	29	29	NUM
bjp-23039	14	46	journal	journal	NOUN
bjp-23039	14	47	homepage	homepage	NOUN
bjp-23039	14	48	:	:	PUNCT
bjp-23039	14	49	www.banglajol.info	www.banglajol.info	PROPN
bjp-23039	14	50	abstracted	abstract	VERB
bjp-23039	14	51	/	/	SYM
bjp-23039	14	52	indexed	index	VERB
bjp-23039	14	53	in	in	ADP
bjp-23039	14	54	academic	academic	ADJ
bjp-23039	14	55	search	search	NOUN
bjp-23039	14	56	complete	complete	ADJ
bjp-23039	14	57	,	,	PUNCT
bjp-23039	14	58	agroforestry	agroforestry	NOUN
bjp-23039	14	59	abstracts	abstract	NOUN
bjp-23039	14	60	,	,	PUNCT
bjp-23039	14	61	asia	asia	PROPN
bjp-23039	14	62	journals	journal	NOUN
bjp-23039	14	63	online	online	ADV
bjp-23039	14	64	,	,	PUNCT
bjp-23039	14	65	bangladesh	bangladesh	NOUN
bjp-23039	14	66	journals	journal	NOUN
bjp-23039	14	67	online	online	ADV
bjp-23039	14	68	,	,	PUNCT
bjp-23039	14	69	biological	biological	ADJ
bjp-23039	14	70	abstracts	abstract	NOUN
bjp-23039	14	71	,	,	PUNCT
bjp-23039	14	72	biosis	biosis	NOUN
bjp-23039	14	73	previews	preview	NOUN
bjp-23039	14	74	,	,	PUNCT
bjp-23039	14	75	cab	cab	NOUN
bjp-23039	14	76	abstracts	abstract	NOUN
bjp-23039	14	77	,	,	PUNCT
bjp-23039	14	78	current	current	ADJ
bjp-23039	14	79	abstracts	abstract	NOUN
bjp-23039	14	80	,	,	PUNCT
bjp-23039	14	81	directory	directory	NOUN
bjp-23039	14	82	of	of	ADP
bjp-23039	14	83	open	open	ADJ
bjp-23039	14	84	access	access	NOUN
bjp-23039	14	85	journals	journal	NOUN
bjp-23039	14	86	,	,	PUNCT
bjp-23039	14	87	embase	embase	NOUN
bjp-23039	14	88	/	/	SYM
bjp-23039	14	89	excerpta	excerpta	NOUN
bjp-23039	14	90	medica	medica	NOUN
bjp-23039	14	91	,	,	PUNCT
bjp-23039	14	92	google	google	PROPN
bjp-23039	14	93	scholar	scholar	NOUN
bjp-23039	14	94	,	,	PUNCT
bjp-23039	14	95	hinari	hinari	X
bjp-23039	14	96	(	(	PUNCT
bjp-23039	14	97	who	who	PRON
bjp-23039	14	98	)	)	PUNCT
bjp-23039	14	99	,	,	PUNCT
bjp-23039	14	100	international	international	ADJ
bjp-23039	14	101	pharmaceutical	pharmaceutical	ADJ
bjp-23039	14	102	abstracts	abstract	NOUN
bjp-23039	14	103	,	,	PUNCT
bjp-23039	14	104	open	open	ADJ
bjp-23039	14	105	j	j	PROPN
bjp-23039	14	106	-	-	PUNCT
bjp-23039	14	107	gate	gate	NOUN
bjp-23039	14	108	,	,	PUNCT
bjp-23039	14	109	science	science	NOUN
bjp-23039	14	110	citation	citation	NOUN
bjp-23039	14	111	index	index	NOUN
bjp-23039	14	112	expanded	expand	VERB
bjp-23039	14	113	,	,	PUNCT
bjp-23039	14	114	scopus	scopus	NOUN
bjp-23039	14	115	and	and	CCONJ
bjp-23039	14	116	social	social	ADJ
bjp-23039	14	117	sciences	sciences	PROPN
bjp-23039	14	118	citation	citation	NOUN
bjp-23039	14	119	index	index	NOUN
bjp-23039	14	120	;	;	PUNCT
bjp-23039	14	121	issn	issn	PROPN
bjp-23039	14	122	:	:	PUNCT
bjp-23039	14	123	1991	1991	NUM
bjp-23039	14	124	-	-	PUNCT
bjp-23039	14	125	0088	0088	NUM
bjp-23039	14	126	abstract	abstract	ADJ
bjp-23039	14	127	human	human	ADJ
bjp-23039	14	128	osteosarcoma	osteosarcoma	NOUN
bjp-23039	14	129	is	be	AUX
bjp-23039	14	130	the	the	DET
bjp-23039	14	131	most	most	ADV
bjp-23039	14	132	prevalent	prevalent	ADJ
bjp-23039	14	133	primary	primary	ADJ
bjp-23039	14	134	malignant	malignant	ADJ
bjp-23039	14	135	bone	bone	NOUN
bjp-23039	14	136	tumor	tumor	NOUN
bjp-23039	14	137	with	with	ADP
bjp-23039	14	138	high	high	ADJ
bjp-23039	14	139	frequency	frequency	NOUN
bjp-23039	14	140	of	of	ADP
bjp-23039	14	141	invasion	invasion	NOUN
bjp-23039	14	142	and	and	CCONJ
bjp-23039	14	143	metastasis	metastasis	NOUN
bjp-23039	14	144	.	.	PUNCT
bjp-23039	15	1	strong	strong	ADJ
bjp-23039	15	2	resistance	resistance	NOUN
bjp-23039	15	3	coupled	couple	VERB
bjp-23039	15	4	with	with	ADP
bjp-23039	15	5	toxicity	toxicity	NOUN
bjp-23039	15	6	of	of	ADP
bjp-23039	15	7	the	the	DET
bjp-23039	15	8	currently	currently	ADV
bjp-23039	15	9	available	available	ADJ
bjp-23039	15	10	chemotherapeutic	chemotherapeutic	ADJ
bjp-23039	15	11	drugs	drug	NOUN
bjp-23039	15	12	poses	pose	NOUN
bjp-23039	15	13	challenge	challenge	VERB
bjp-23039	15	14	in	in	ADP
bjp-23039	15	15	treatment	treatment	NOUN
bjp-23039	15	16	.	.	PUNCT
bjp-23039	16	1	the	the	DET
bjp-23039	16	2	study	study	NOUN
bjp-23039	16	3	aimed	aim	VERB
bjp-23039	16	4	to	to	PART
bjp-23039	16	5	investigate	investigate	VERB
bjp-23039	16	6	if	if	SCONJ
bjp-23039	16	7	fisetin	fisetin	NOUN
bjp-23039	16	8	,	,	PUNCT
bjp-23039	16	9	a	a	DET
bjp-23039	16	10	dietary	dietary	ADJ
bjp-23039	16	11	flavonoid	flavonoid	NOUN
bjp-23039	16	12	induced	induce	VERB
bjp-23039	16	13	apoptosis	apoptosis	NOUN
bjp-23039	16	14	in	in	ADP
bjp-23039	16	15	human	human	ADJ
bjp-23039	16	16	osteosarcoma	osteosarcoma	X
bjp-23039	16	17	(	(	PUNCT
bjp-23039	16	18	u-2	u-2	PROPN
bjp-23039	16	19	os	os	NOUN
bjp-23039	16	20	)	)	PUNCT
bjp-23039	16	21	cells	cell	NOUN
bjp-23039	16	22	.	.	PUNCT
bjp-23039	17	1	fisetin	fisetin	NOUN
bjp-23039	17	2	at	at	ADP
bjp-23039	17	3	20	20	NUM
bjp-23039	17	4	-	-	SYM
bjp-23039	17	5	100	100	NUM
bjp-23039	17	6	µm	µm	ADP
bjp-23039	17	7	effectively	effectively	ADV
bjp-23039	17	8	reduced	reduce	VERB
bjp-23039	17	9	the	the	DET
bjp-23039	17	10	viability	viability	NOUN
bjp-23039	17	11	of	of	ADP
bjp-23039	17	12	os	os	NOUN
bjp-23039	17	13	cells	cell	NOUN
bjp-23039	17	14	,	,	PUNCT
bjp-23039	17	15	and	and	CCONJ
bjp-23039	17	16	induced	induce	VERB
bjp-23039	17	17	apoptosis	apoptosis	NOUN
bjp-23039	17	18	by	by	ADP
bjp-23039	17	19	significantly	significantly	ADV
bjp-23039	17	20	inducing	induce	VERB
bjp-23039	17	21	the	the	DET
bjp-23039	17	22	expression	expression	NOUN
bjp-23039	17	23	of	of	ADP
bjp-23039	17	24	caspases	caspase	NOUN
bjp-23039	17	25	(	(	PUNCT
bjp-23039	17	26	caspases3,-8	caspases3,-8	PROPN
bjp-23039	17	27	and	and	CCONJ
bjp-23039	17	28	-9	-9	NUM
bjp-23039	17	29	)	)	PUNCT
bjp-23039	17	30	and	and	CCONJ
bjp-23039	17	31	proapoptotic	proapoptotic	ADJ
bjp-23039	17	32	proteins	protein	NOUN
bjp-23039	17	33	(	(	PUNCT
bjp-23039	17	34	bax	bax	NOUN
bjp-23039	17	35	and	and	CCONJ
bjp-23039	17	36	bad	bad	ADJ
bjp-23039	17	37	)	)	PUNCT
bjp-23039	17	38	with	with	ADP
bjp-23039	17	39	subsequent	subsequent	ADJ
bjp-23039	17	40	down	down	NOUN
bjp-23039	17	41	-	-	PUNCT
bjp-23039	17	42	regulation	regulation	NOUN
bjp-23039	17	43	of	of	ADP
bjp-23039	17	44	bcl	bcl	PROPN
bjp-23039	17	45	-	-	PROPN
bjp-23039	17	46	xl	xl	PROPN
bjp-23039	17	47	and	and	CCONJ
bjp-23039	17	48	bcl-2	bcl-2	NOUN
bjp-23039	17	49	.	.	PUNCT
bjp-23039	18	1	while	while	SCONJ
bjp-23039	18	2	fisetin	fisetin	ADJ
bjp-23039	18	3	inhibited	inhibit	VERB
bjp-23039	18	4	pi3k	pi3k	PROPN
bjp-23039	18	5	/	/	SYM
bjp-23039	18	6	akt	akt	PROPN
bjp-23039	18	7	pathway	pathway	NOUN
bjp-23039	18	8	and	and	CCONJ
bjp-23039	18	9	erk1/2	erk1/2	PROPN
bjp-23039	18	10	,	,	PUNCT
bjp-23039	18	11	it	it	PRON
bjp-23039	18	12	caused	cause	VERB
bjp-23039	18	13	enhanced	enhanced	ADJ
bjp-23039	18	14	expressions	expression	NOUN
bjp-23039	18	15	of	of	ADP
bjp-23039	18	16	p	p	PROPN
bjp-23039	18	17	-	-	PUNCT
bjp-23039	18	18	jnk	jnk	PROPN
bjp-23039	18	19	,	,	PUNCT
bjp-23039	18	20	p	p	PROPN
bjp-23039	18	21	-	-	PUNCT
bjp-23039	18	22	c	c	NOUN
bjp-23039	18	23	-	-	PUNCT
bjp-23039	18	24	jun	jun	PROPN
bjp-23039	18	25	and	and	CCONJ
bjp-23039	18	26	p	p	NOUN
bjp-23039	18	27	-	-	PUNCT
bjp-23039	18	28	p38	p38	NOUN
bjp-23039	18	29	.	.	PUNCT
bjp-23039	18	30	fisetin	fisetin	NOUN
bjp-23039	18	31	-	-	PUNCT
bjp-23039	18	32	induced	induce	VERB
bjp-23039	18	33	ros	ros	PROPN
bjp-23039	18	34	generation	generation	NOUN
bjp-23039	18	35	and	and	CCONJ
bjp-23039	18	36	decrease	decrease	NOUN
bjp-23039	18	37	in	in	ADP
bjp-23039	18	38	mitochondrial	mitochondrial	ADJ
bjp-23039	18	39	membrane	membrane	NOUN
bjp-23039	18	40	potential	potential	NOUN
bjp-23039	18	41	would	would	AUX
bjp-23039	18	42	have	have	AUX
bjp-23039	18	43	also	also	ADV
bjp-23039	18	44	contributed	contribute	VERB
bjp-23039	18	45	to	to	PART
bjp-23039	18	46	rise	rise	VERB
bjp-23039	18	47	in	in	ADP
bjp-23039	18	48	apoptotic	apoptotic	ADJ
bjp-23039	18	49	cell	cell	NOUN
bjp-23039	18	50	counts	count	NOUN
bjp-23039	18	51	.	.	PUNCT
bjp-23039	19	1	the	the	DET
bjp-23039	19	2	observations	observation	NOUN
bjp-23039	19	3	suggest	suggest	VERB
bjp-23039	19	4	that	that	SCONJ
bjp-23039	19	5	fisetin	fisetin	NOUN
bjp-23039	19	6	was	be	AUX
bjp-23039	19	7	able	able	ADJ
bjp-23039	19	8	to	to	PART
bjp-23039	19	9	effectively	effectively	ADV
bjp-23039	19	10	induce	induce	VERB
bjp-23039	19	11	apoptosis	apoptosis	NOUN
bjp-23039	19	12	of	of	ADP
bjp-23039	19	13	u-2	u-2	PROPN
bjp-23039	19	14	os	os	PROPN
bjp-23039	19	15	cells	cell	NOUN
bjp-23039	19	16	through	through	ADP
bjp-23039	19	17	ros	ros	PROPN
bjp-23039	19	18	generation	generation	NOUN
bjp-23039	19	19	and	and	CCONJ
bjp-23039	19	20	modulation	modulation	NOUN
bjp-23039	19	21	of	of	ADP
bjp-23039	19	22	mapk	mapk	NOUN
bjp-23039	19	23	and	and	CCONJ
bjp-23039	19	24	pi3k	pi3k	PROPN
bjp-23039	19	25	/	/	SYM
bjp-23039	19	26	akt	akt	PROPN
bjp-23039	19	27	signalling	signal	VERB
bjp-23039	19	28	cascades	cascade	NOUN
bjp-23039	19	29	.	.	PUNCT
bjp-23039	20	1	article	article	NOUN
bjp-23039	20	2	info	info	NOUN
bjp-23039	20	3	received	receive	VERB
bjp-23039	20	4	:	:	PUNCT
bjp-23039	20	5	20	20	NUM
bjp-23039	20	6	april	april	PROPN
bjp-23039	20	7	2015	2015	NUM
bjp-23039	20	8	accepted	accept	VERB
bjp-23039	20	9	:	:	PUNCT
bjp-23039	20	10	23	23	NUM
bjp-23039	20	11	may	may	PROPN
bjp-23039	20	12	2015	2015	NUM
bjp-23039	20	13	available	available	ADJ
bjp-23039	20	14	online	online	NOUN
bjp-23039	20	15	:	:	PUNCT
bjp-23039	20	16	2	2	NUM
bjp-23039	20	17	october	october	PROPN
bjp-23039	20	18	2015	2015	NUM
bjp-23039	20	19	doi	doi	NOUN
bjp-23039	20	20	:	:	PUNCT
bjp-23039	20	21	10.3329	10.3329	NUM
bjp-23039	20	22	/	/	SYM
bjp-23039	20	23	bjp.v10i4.23039	bjp.v10i4.23039	PROPN
bjp-23039	20	24	cite	cite	VERB
bjp-23039	20	25	this	this	DET
bjp-23039	20	26	article	article	NOUN
bjp-23039	20	27	:	:	PUNCT
bjp-23039	20	28	li	li	PROPN
bjp-23039	20	29	jm	jm	PROPN
bjp-23039	20	30	,	,	PUNCT
bjp-23039	20	31	li	li	PROPN
bjp-23039	20	32	wy	wy	PROPN
bjp-23039	20	33	,	,	PUNCT
bjp-23039	20	34	huang	huang	PROPN
bjp-23039	20	35	my	my	PROPN
bjp-23039	20	36	,	,	PUNCT
bjp-23039	20	37	zhang	zhang	PROPN
bjp-23039	20	38	xq	xq	PROPN
bjp-23039	20	39	.	.	PROPN
bjp-23039	20	40	fisetin	fisetin	PROPN
bjp-23039	20	41	,	,	PUNCT
bjp-23039	20	42	a	a	DET
bjp-23039	20	43	dietary	dietary	ADJ
bjp-23039	20	44	flavonoid	flavonoid	NOUN
bjp-23039	20	45	induces	induce	VERB
bjp-23039	20	46	apoptosis	apoptosis	NOUN
bjp-23039	20	47	via	via	ADP
bjp-23039	20	48	modulating	modulate	VERB
bjp-23039	20	49	the	the	DET
bjp-23039	20	50	mapk	mapk	NOUN
bjp-23039	20	51	and	and	CCONJ
bjp-23039	20	52	pi3k	pi3k	PROPN
bjp-23039	20	53	/	/	SYM
bjp-23039	20	54	akt	akt	PROPN
bjp-23039	20	55	signalling	signal	VERB
bjp-23039	20	56	pathways	pathway	NOUN
bjp-23039	20	57	in	in	ADP
bjp-23039	20	58	human	human	ADJ
bjp-23039	20	59	osteosarcoma	osteosarcoma	X
bjp-23039	20	60	(	(	PUNCT
bjp-23039	20	61	u-2	u-2	PROPN
bjp-23039	20	62	os	os	NOUN
bjp-23039	20	63	)	)	PUNCT
bjp-23039	20	64	cells	cell	NOUN
bjp-23039	20	65	.	.	PUNCT
bjp-23039	21	1	bangladesh	bangladesh	PROPN
bjp-23039	21	2	j	j	PROPN
bjp-23039	21	3	pharmacol	pharmacol	PROPN
bjp-23039	21	4	.	.	PROPN
bjp-23039	22	1	2015	2015	NUM
bjp-23039	22	2	;	;	PUNCT
bjp-23039	22	3	10	10	NUM
bjp-23039	22	4	:	:	SYM
bjp-23039	22	5	820	820	NUM
bjp-23039	22	6	-29	-29	SYM
bjp-23039	22	7	.	.	PUNCT
bjp-23039	22	8	fisetin	fisetin	PROPN
bjp-23039	22	9	,	,	PUNCT
bjp-23039	22	10	a	a	DET
bjp-23039	22	11	dietary	dietary	ADJ
bjp-23039	22	12	flavonoid	flavonoid	NOUN
bjp-23039	22	13	induces	induce	VERB
bjp-23039	22	14	apoptosis	apoptosis	NOUN
bjp-23039	22	15	via	via	ADP
bjp-23039	22	16	modulating	modulate	VERB
bjp-23039	22	17	the	the	DET
bjp-23039	22	18	mapk	mapk	NOUN
bjp-23039	22	19	and	and	CCONJ
bjp-23039	22	20	pi3k	pi3k	PROPN
bjp-23039	22	21	/	/	SYM
bjp-23039	22	22	akt	akt	PROPN
bjp-23039	22	23	signalling	signal	VERB
bjp-23039	22	24	pathways	pathway	NOUN
bjp-23039	22	25	in	in	ADP
bjp-23039	22	26	human	human	ADJ
bjp-23039	22	27	osteosarcoma	osteosarcoma	X
bjp-23039	22	28	(	(	PUNCT
bjp-23039	22	29	u-2	u-2	PROPN
bjp-23039	22	30	os	os	NOUN
bjp-23039	22	31	)	)	PUNCT
bjp-23039	22	32	cells	cell	NOUN
bjp-23039	22	33	jian	jian	PROPN
bjp-23039	22	34	-	-	PUNCT
bjp-23039	22	35	ming	ming	ADJ
bjp-23039	22	36	li1	li1	NOUN
bjp-23039	22	37	,	,	PUNCT
bjp-23039	22	38	wu	wu	PROPN
bjp-23039	22	39	-	-	PUNCT
bjp-23039	22	40	yin	yin	PROPN
bjp-23039	22	41	li1	li1	NOUN
bjp-23039	22	42	,	,	PUNCT
bjp-23039	22	43	man	man	NOUN
bjp-23039	22	44	-	-	PUNCT
bjp-23039	22	45	yu	yu	PROPN
bjp-23039	22	46	huang1	huang1	PROPN
bjp-23039	22	47	and	and	CCONJ
bjp-23039	22	48	xiao	xiao	PROPN
bjp-23039	22	49	-	-	PUNCT
bjp-23039	22	50	qiang	qiang	PROPN
bjp-23039	22	51	zhang2	zhang2	PROPN
bjp-23039	23	1	1department	1department	NUM
bjp-23039	23	2	of	of	ADP
bjp-23039	23	3	hip	hip	NOUN
bjp-23039	23	4	traumatology	traumatology	NOUN
bjp-23039	23	5	and	and	CCONJ
bjp-23039	23	6	2orthopedics	2orthopedic	NOUN
bjp-23039	23	7	,	,	PUNCT
bjp-23039	23	8	luoyang	luoyang	PROPN
bjp-23039	23	9	orthopedic	orthopedic	PROPN
bjp-23039	23	10	-	-	PUNCT
bjp-23039	23	11	traumato	traumato	PROPN
bjp-23039	23	12	logical	logical	ADJ
bjp-23039	23	13	hospital	hospital	NOUN
bjp-23039	23	14	,	,	PUNCT
bjp-23039	23	15	luoyang	luoyang	PROPN
bjp-23039	23	16	471	471	NUM
bjp-23039	23	17	002	002	NUM
bjp-23039	23	18	,	,	PUNCT
bjp-23039	23	19	china	china	PROPN
bjp-23039	23	20	.	.	PROPN
bjp-23039	23	21	2015	2015	NUM
bjp-23039	23	22	;	;	PUNCT
bjp-23039	23	23	zhao	zhao	PROPN
bjp-23039	23	24	et	et	PROPN
bjp-23039	23	25	al	al	PROPN
bjp-23039	23	26	.	.	PROPN
bjp-23039	23	27	,	,	PUNCT
bjp-23039	23	28	2015	2015	NUM
bjp-23039	23	29	)	)	PUNCT
bjp-23039	23	30	.	.	PUNCT
bjp-23039	24	1	recent	recent	ADJ
bjp-23039	24	2	research	research	NOUN
bjp-23039	24	3	have	have	AUX
bjp-23039	24	4	reported	report	VERB
bjp-23039	24	5	anti	anti	ADJ
bjp-23039	24	6	-	-	ADJ
bjp-23039	24	7	proliferative	proliferative	ADJ
bjp-23039	24	8	(	(	PUNCT
bjp-23039	24	9	chen	chen	PROPN
bjp-23039	24	10	et	et	PROPN
bjp-23039	24	11	al	al	PROPN
bjp-23039	24	12	.	.	PROPN
bjp-23039	24	13	,	,	PUNCT
bjp-23039	24	14	2002	2002	NUM
bjp-23039	24	15	;	;	PUNCT
bjp-23039	24	16	haddad	haddad	PROPN
bjp-23039	24	17	et	et	PROPN
bjp-23039	24	18	al	al	PROPN
bjp-23039	24	19	.	.	PROPN
bjp-23039	24	20	,	,	PUNCT
bjp-23039	24	21	2006	2006	NUM
bjp-23039	24	22	)	)	PUNCT
bjp-23039	24	23	and	and	CCONJ
bjp-23039	24	24	anti	anti	ADJ
bjp-23039	24	25	-	-	ADJ
bjp-23039	24	26	metastasic	metastasic	ADJ
bjp-23039	24	27	effects	effect	NOUN
bjp-23039	24	28	(	(	PUNCT
bjp-23039	24	29	chou	chou	NOUN
bjp-23039	24	30	et	et	PROPN
bjp-23039	24	31	al	al	PROPN
bjp-23039	24	32	.	.	PROPN
bjp-23039	24	33	,	,	PUNCT
bjp-23039	24	34	2013	2013	NUM
bjp-23039	24	35	)	)	PUNCT
bjp-23039	24	36	of	of	ADP
bjp-23039	24	37	fisetin	fisetin	NOUN
bjp-23039	24	38	,	,	PUNCT
bjp-23039	24	39	a	a	DET
bjp-23039	24	40	polyphenolic	polyphenolic	ADJ
bjp-23039	24	41	flavonoid	flavonoid	NOUN
bjp-23039	24	42	present	present	ADJ
bjp-23039	24	43	in	in	ADP
bjp-23039	24	44	many	many	ADJ
bjp-23039	24	45	fruits	fruit	NOUN
bjp-23039	24	46	such	such	ADJ
bjp-23039	24	47	as	as	ADP
bjp-23039	24	48	strawberries	strawberry	NOUN
bjp-23039	24	49	and	and	CCONJ
bjp-23039	24	50	cucumbers	cucumber	NOUN
bjp-23039	24	51	(	(	PUNCT
bjp-23039	24	52	kim	kim	PROPN
bjp-23039	24	53	et	et	PROPN
bjp-23039	24	54	al	al	PROPN
bjp-23039	24	55	.	.	PROPN
bjp-23039	24	56	,	,	PUNCT
bjp-23039	24	57	2012	2012	NUM
bjp-23039	24	58	)	)	PUNCT
bjp-23039	24	59	.	.	PUNCT
bjp-23039	25	1	mechanisms	mechanism	NOUN
bjp-23039	25	2	through	through	ADP
bjp-23039	25	3	which	which	PRON
bjp-23039	25	4	fisetin	fisetin	NOUN
bjp-23039	25	5	exerts	exert	VERB
bjp-23039	25	6	its	its	PRON
bjp-23039	25	7	action	action	NOUN
bjp-23039	25	8	is	be	AUX
bjp-23039	25	9	yet	yet	ADV
bjp-23039	25	10	to	to	PART
bjp-23039	25	11	be	be	AUX
bjp-23039	25	12	elucidated	elucidate	VERB
bjp-23039	25	13	completely	completely	ADV
bjp-23039	25	14	,	,	PUNCT
bjp-23039	25	15	although	although	SCONJ
bjp-23039	25	16	it	it	PRON
bjp-23039	25	17	has	have	AUX
bjp-23039	25	18	been	be	AUX
bjp-23039	25	19	demonstrated	demonstrate	VERB
bjp-23039	25	20	to	to	PART
bjp-23039	25	21	increase	increase	VERB
bjp-23039	25	22	expressions	expression	NOUN
bjp-23039	25	23	of	of	ADP
bjp-23039	25	24	p53	p53	NOUN
bjp-23039	25	25	,	,	PUNCT
bjp-23039	25	26	down	down	ADV
bjp-23039	25	27	-	-	PUNCT
bjp-23039	25	28	regulate	regulate	VERB
bjp-23039	25	29	cyclin	cyclin	NOUN
bjp-23039	25	30	d1	d1	PROPN
bjp-23039	25	31	and	and	CCONJ
bjp-23039	25	32	cyclin	cyclin	NOUN
bjp-23039	25	33	e	e	PROPN
bjp-23039	25	34	levels	level	NOUN
bjp-23039	25	35	(	(	PUNCT
bjp-23039	25	36	chen	chen	PROPN
bjp-23039	25	37	et	et	PROPN
bjp-23039	25	38	al	al	PROPN
bjp-23039	25	39	.	.	PROPN
bjp-23039	25	40	,	,	PUNCT
bjp-23039	25	41	2002	2002	NUM
bjp-23039	25	42	;	;	PUNCT
bjp-23039	25	43	lee	lee	PROPN
bjp-23039	25	44	et	et	PROPN
bjp-23039	25	45	al	al	PROPN
bjp-23039	25	46	.	.	PROPN
bjp-23039	25	47	,	,	PUNCT
bjp-23039	25	48	2002	2002	NUM
bjp-23039	25	49	;	;	PUNCT
bjp-23039	26	1	lu	lu	PROPN
bjp-23039	26	2	et	et	PROPN
bjp-23039	26	3	al	al	PROPN
bjp-23039	26	4	.	.	PROPN
bjp-23039	26	5	,	,	PUNCT
bjp-23039	26	6	2005b	2005b	NUM
bjp-23039	26	7	;	;	PUNCT
bjp-23039	26	8	haddad	haddad	PROPN
bjp-23039	26	9	et	et	PROPN
bjp-23039	26	10	al	al	PROPN
bjp-23039	26	11	.	.	PROPN
bjp-23039	26	12	,	,	PUNCT
bjp-23039	26	13	2006	2006	NUM
bjp-23039	26	14	)	)	PUNCT
bjp-23039	26	15	.	.	PUNCT
bjp-23039	27	1	present	present	ADJ
bjp-23039	27	2	study	study	NOUN
bjp-23039	27	3	investigates	investigate	VERB
bjp-23039	27	4	whether	whether	SCONJ
bjp-23039	27	5	fisetin	fisetin	ADJ
bjp-23039	27	6	induces	induce	NOUN
bjp-23039	27	7	apoptosis	apoptosis	NOUN
bjp-23039	27	8	of	of	ADP
bjp-23039	27	9	human	human	ADJ
bjp-23039	27	10	osteosarcoma	osteosarcoma	ADJ
bjp-23039	27	11	cells	cell	NOUN
bjp-23039	27	12	and	and	CCONJ
bjp-23039	27	13	modulats	modulat	VERB
bjp-23039	27	14	the	the	DET
bjp-23039	27	15	mapk	mapk	NOUN
bjp-23039	27	16	and	and	CCONJ
bjp-23039	27	17	pi3	pi3	NOUN
bjp-23039	27	18	/	/	SYM
bjp-23039	27	19	akt	akt	NOUN
bjp-23039	27	20	signalling	signal	VERB
bjp-23039	27	21	pathways	pathway	NOUN
bjp-23039	27	22	.	.	PUNCT
bjp-23039	28	1	materials	material	NOUN
bjp-23039	28	2	and	and	CCONJ
bjp-23039	28	3	methods	method	NOUN
bjp-23039	28	4	cell	cell	NOUN
bjp-23039	28	5	lines	line	NOUN
bjp-23039	28	6	the	the	DET
bjp-23039	28	7	human	human	ADJ
bjp-23039	28	8	osteosarcoma	osteosarcoma	ADJ
bjp-23039	28	9	cell	cell	NOUN
bjp-23039	28	10	line	line	NOUN
bjp-23039	28	11	u-2	u-2	PROPN
bjp-23039	28	12	os	os	PROPN
bjp-23039	28	13	(	(	PUNCT
bjp-23039	28	14	htb-96tm	htb-96tm	NUM
bjp-23039	28	15	,	,	PUNCT
bjp-23039	28	16	atcc	atcc	NOUN
bjp-23039	28	17	)	)	PUNCT
bjp-23039	28	18	was	be	AUX
bjp-23039	28	19	obtained	obtain	VERB
bjp-23039	28	20	from	from	ADP
bjp-23039	28	21	cell	cell	NOUN
bjp-23039	28	22	bank	bank	PROPN
bjp-23039	28	23	of	of	ADP
bjp-23039	28	24	shanghai	shanghai	PROPN
bjp-23039	28	25	institute	institute	PROPN
bjp-23039	28	26	of	of	ADP
bjp-23039	28	27	biochemistry	biochemistry	PROPN
bjp-23039	28	28	and	and	CCONJ
bjp-23039	28	29	cell	cell	NOUN
bjp-23039	28	30	biology	biology	NOUN
bjp-23039	28	31	,	,	PUNCT
bjp-23039	28	32	chinese	chinese	PROPN
bjp-23039	28	33	academy	academy	PROPN
bjp-23039	28	34	of	of	ADP
bjp-23039	28	35	sciences	sciences	PROPN
bjp-23039	28	36	(	(	PUNCT
bjp-23039	28	37	shanghai	shanghai	PROPN
bjp-23039	28	38	,	,	PUNCT
bjp-23039	28	39	china	china	PROPN
bjp-23039	28	40	)	)	PUNCT
bjp-23039	28	41	.	.	PUNCT
bjp-23039	29	1	the	the	DET
bjp-23039	29	2	cells	cell	NOUN
bjp-23039	29	3	were	be	AUX
bjp-23039	29	4	maintained	maintain	VERB
bjp-23039	29	5	in	in	ADP
bjp-23039	29	6	rpmi-1640	rpmi-1640	ADJ
bjp-23039	29	7	medium	medium	NOUN
bjp-23039	29	8	supplemented	supplement	VERB
bjp-23039	29	9	with	with	ADP
bjp-23039	29	10	10	10	NUM
bjp-23039	29	11	%	%	NOUN
bjp-23039	29	12	fetal	fetal	ADJ
bjp-23039	29	13	calf	calf	NOUN
bjp-23039	29	14	serum	serum	NOUN
bjp-23039	29	15	(	(	PUNCT
bjp-23039	29	16	fcs	fcs	PROPN
bjp-23039	29	17	)	)	PUNCT
bjp-23039	29	18	,	,	PUNCT
bjp-23039	29	19	streptomycin	streptomycin	PROPN
bjp-23039	29	20	(	(	PUNCT
bjp-23039	29	21	100	100	NUM
bjp-23039	29	22	μg	μg	NOUN
bjp-23039	29	23	/	/	SYM
bjp-23039	29	24	ml	ml	NOUN
bjp-23039	29	25	)	)	PUNCT
bjp-23039	29	26	,	,	PUNCT
bjp-23039	29	27	2	2	NUM
bjp-23039	29	28	mm	mm	NOUN
bjp-23039	29	29	glutamine	glutamine	NOUN
bjp-23039	29	30	and	and	CCONJ
bjp-23039	29	31	penicillin	penicillin	NOUN
bjp-23039	29	32	(	(	PUNCT
bjp-23039	29	33	100	100	NUM
bjp-23039	29	34	u	u	NOUN
bjp-23039	29	35	/	/	SYM
bjp-23039	29	36	ml	ml	NOUN
bjp-23039	29	37	)	)	PUNCT
bjp-23039	29	38	at	at	ADP
bjp-23039	29	39	37	37	NUM
bjp-23039	29	40	°	°	ADP
bjp-23039	29	41	c	c	NOUN
bjp-23039	29	42	in	in	ADP
bjp-23039	29	43	a	a	DET
bjp-23039	29	44	humidified	humidify	VERB
bjp-23039	29	45	atmosphere	atmosphere	NOUN
bjp-23039	29	46	with	with	ADP
bjp-23039	29	47	5	5	NUM
bjp-23039	29	48	%	%	NOUN
bjp-23039	29	49	co2	co2	NOUN
bjp-23039	29	50	.	.	PUNCT
bjp-23039	30	1	reagents	reagent	NOUN
bjp-23039	30	2	and	and	CCONJ
bjp-23039	30	3	chemicals	chemical	NOUN
bjp-23039	30	4	:	:	PUNCT
bjp-23039	30	5	fisetin	fisetin	NOUN
bjp-23039	30	6	,	,	PUNCT
bjp-23039	30	7	glutamine	glutamine	NOUN
bjp-23039	30	8	,	,	PUNCT
bjp-23039	30	9	rpmi1640	rpmi1640	PROPN
bjp-23039	30	10	medium	medium	ADJ
bjp-23039	30	11	,	,	PUNCT
bjp-23039	30	12	fetal	fetal	ADJ
bjp-23039	30	13	calf	calf	NOUN
bjp-23039	30	14	serum	serum	NOUN
bjp-23039	30	15	(	(	PUNCT
bjp-23039	30	16	fcs	fcs	PROPN
bjp-23039	30	17	)	)	PUNCT
bjp-23039	30	18	,	,	PUNCT
bjp-23039	30	19	penicillin	penicillin	NOUN
bjp-23039	30	20	,	,	PUNCT
bjp-23039	30	21	streptomycin	streptomycin	PROPN
bjp-23039	30	22	,	,	PUNCT
bjp-23039	30	23	pbs	pbs	PROPN
bjp-23039	30	24	and	and	CCONJ
bjp-23039	30	25	0.25	0.25	NUM
bjp-23039	30	26	%	%	NOUN
bjp-23039	30	27	trypsin	trypsin	NOUN
bjp-23039	30	28	were	be	AUX
bjp-23039	30	29	purchased	purchase	VERB
bjp-23039	30	30	from	from	ADP
bjp-23039	30	31	sigma	sigma	PROPN
bjp-23039	30	32	aldrich	aldrich	PROPN
bjp-23039	30	33	(	(	PUNCT
bjp-23039	30	34	st.louis	st.louis	PROPN
bjp-23039	30	35	,	,	PUNCT
bjp-23039	30	36	mo	mo	PROPN
bjp-23039	30	37	,	,	PUNCT
bjp-23039	30	38	usa	usa	PROPN
bjp-23039	30	39	)	)	PUNCT
bjp-23039	30	40	.	.	PUNCT
bjp-23039	31	1	antibodies	antibodie	VERB
bjp-23039	31	2	against	against	ADP
bjp-23039	31	3	erk1/2	erk1/2	PROPN
bjp-23039	31	4	,	,	PUNCT
bjp-23039	31	5	phosphoerk1/2	phosphoerk1/2	NOUN
bjp-23039	31	6	,	,	PUNCT
bjp-23039	31	7	p38	p38	NOUN
bjp-23039	31	8	,	,	PUNCT
bjp-23039	31	9	phospho	phospho	NOUN
bjp-23039	31	10	-	-	PUNCT
bjp-23039	31	11	p38	p38	NOUN
bjp-23039	31	12	,	,	PUNCT
bjp-23039	31	13	jnk	jnk	PROPN
bjp-23039	31	14	,	,	PUNCT
bjp-23039	31	15	phospho	phospho	NOUN
bjp-23039	31	16	-	-	PUNCT
bjp-23039	31	17	jnk	jnk	NOUN
bjp-23039	31	18	,	,	PUNCT
bjp-23039	31	19	c	c	PROPN
bjp-23039	31	20	-	-	PUNCT
bjp-23039	31	21	jun	jun	PROPN
bjp-23039	31	22	,	,	PUNCT
bjp-23039	31	23	phospho	phospho	ADJ
bjp-23039	31	24	-	-	PUNCT
bjp-23039	31	25	c	c	NOUN
bjp-23039	31	26	-	-	PUNCT
bjp-23039	31	27	jun	jun	PROPN
bjp-23039	31	28	,	,	PUNCT
bjp-23039	31	29	akt	akt	PROPN
bjp-23039	31	30	,	,	PUNCT
bjp-23039	31	31	phospho	phospho	NOUN
bjp-23039	31	32	-	-	PUNCT
bjp-23039	31	33	akt	akt	NOUN
bjp-23039	31	34	,	,	PUNCT
bjp-23039	31	35	gsk3β	gsk3β	PROPN
bjp-23039	31	36	(	(	PUNCT
bjp-23039	31	37	glycogensynthase	glycogensynthase	PROPN
bjp-23039	31	38	kinase	kinase	PROPN
bjp-23039	31	39	3β	3β	NUM
bjp-23039	31	40	)	)	PUNCT
bjp-23039	31	41	,	,	PUNCT
bjp-23039	31	42	phospho	phospho	NOUN
bjp-23039	31	43	-	-	PUNCT
bjp-23039	31	44	gsk3β	gsk3β	NOUN
bjp-23039	31	45	)	)	PUNCT
bjp-23039	31	46	,	,	PUNCT
bjp-23039	31	47	nf	nf	PROPN
bjp-23039	31	48	-	-	PUNCT
bjp-23039	31	49	κb	κb	PROPN
bjp-23039	31	50	,	,	PUNCT
bjp-23039	31	51	iκb	iκb	PROPN
bjp-23039	31	52	,	,	PUNCT
bjp-23039	31	53	caspase-3	caspase-3	NUM
bjp-23039	31	54	,	,	PUNCT
bjp-23039	31	55	caspase-8	caspase-8	PROPN
bjp-23039	31	56	,	,	PUNCT
bjp-23039	31	57	caspase-9	caspase-9	PROPN
bjp-23039	31	58	(	(	PUNCT
bjp-23039	31	59	cell	cell	NOUN
bjp-23039	31	60	signaling	signal	VERB
bjp-23039	31	61	technology	technology	NOUN
bjp-23039	31	62	,	,	PUNCT
bjp-23039	31	63	beverly	beverly	PROPN
bjp-23039	31	64	,	,	PUNCT
bjp-23039	31	65	ma	ma	PROPN
bjp-23039	31	66	)	)	PUNCT
bjp-23039	31	67	,	,	PUNCT
bjp-23039	31	68	bcl	bcl	PROPN
bjp-23039	31	69	-	-	PROPN
bjp-23039	31	70	xl	xl	PROPN
bjp-23039	31	71	,	,	PUNCT
bjp-23039	31	72	bcl-2	bcl-2	ADJ
bjp-23039	31	73	,	,	PUNCT
bjp-23039	31	74	bad	bad	ADJ
bjp-23039	31	75	,	,	PUNCT
bjp-23039	31	76	bax	bax	PROPN
bjp-23039	31	77	,	,	PUNCT
bjp-23039	31	78	mtorc1	mtorc1	NOUN
bjp-23039	31	79	,	,	PUNCT
bjp-23039	31	80	cyclind1	cyclind1	NOUN
bjp-23039	31	81	and	and	CCONJ
bjp-23039	31	82	pten	pten	PROPN
bjp-23039	31	83	(	(	PUNCT
bjp-23039	31	84	santa	santa	PROPN
bjp-23039	31	85	cruz	cruz	PROPN
bjp-23039	31	86	,	,	PUNCT
bjp-23039	31	87	biotechnology	biotechnology	PROPN
bjp-23039	31	88	,	,	PUNCT
bjp-23039	31	89	inc	inc	PROPN
bjp-23039	31	90	.	.	PROPN
bjp-23039	31	91	santa	santa	PROPN
bjp-23039	31	92	cruz	cruz	PROPN
bjp-23039	31	93	,	,	PUNCT
bjp-23039	31	94	ca	ca	PROPN
bjp-23039	31	95	,	,	PUNCT
bjp-23039	31	96	usa	usa	PROPN
bjp-23039	31	97	)	)	PUNCT
bjp-23039	31	98	were	be	AUX
bjp-23039	31	99	used	use	VERB
bjp-23039	31	100	in	in	ADP
bjp-23039	31	101	the	the	DET
bjp-23039	31	102	study	study	NOUN
bjp-23039	31	103	.	.	PUNCT
bjp-23039	32	1	other	other	ADJ
bjp-23039	32	2	chemicals	chemical	NOUN
bjp-23039	32	3	and	and	CCONJ
bjp-23039	32	4	reagents	reagent	NOUN
bjp-23039	32	5	used	use	VERB
bjp-23039	32	6	in	in	ADP
bjp-23039	32	7	the	the	DET
bjp-23039	32	8	study	study	NOUN
bjp-23039	32	9	were	be	AUX
bjp-23039	32	10	obtained	obtain	VERB
bjp-23039	32	11	from	from	ADP
bjp-23039	32	12	sigma	sigma	PROPN
bjp-23039	32	13	aldrich	aldrich	PROPN
bjp-23039	32	14	(	(	PUNCT
bjp-23039	32	15	st.louis	st.louis	PROPN
bjp-23039	32	16	,	,	PUNCT
bjp-23039	32	17	mo	mo	PROPN
bjp-23039	32	18	,	,	PUNCT
bjp-23039	32	19	usa	usa	PROPN
bjp-23039	32	20	)	)	PUNCT
bjp-23039	32	21	unless	unless	SCONJ
bjp-23039	32	22	otherwise	otherwise	ADV
bjp-23039	32	23	specified	specify	VERB
bjp-23039	32	24	.	.	PUNCT
bjp-23039	33	1	cell	cell	NOUN
bjp-23039	33	2	viability	viability	NOUN
bjp-23039	33	3	assay	assay	VERB
bjp-23039	33	4	the	the	DET
bjp-23039	33	5	anti	anti	ADJ
bjp-23039	33	6	-	-	ADJ
bjp-23039	33	7	proliferative	proliferative	ADJ
bjp-23039	33	8	effect	effect	NOUN
bjp-23039	33	9	of	of	ADP
bjp-23039	33	10	fisetin	fisetin	NOUN
bjp-23039	33	11	on	on	ADP
bjp-23039	33	12	osteosarcoma	osteosarcoma	ADJ
bjp-23039	33	13	cells	cell	NOUN
bjp-23039	33	14	was	be	AUX
bjp-23039	33	15	determined	determine	VERB
bjp-23039	33	16	using	use	VERB
bjp-23039	33	17	mts	mts	NOUN
bjp-23039	33	18	kit	kit	NOUN
bjp-23039	33	19	(	(	PUNCT
bjp-23039	33	20	promega	promega	PROPN
bjp-23039	33	21	,	,	PUNCT
bjp-23039	33	22	madison	madison	PROPN
bjp-23039	33	23	,	,	PUNCT
bjp-23039	33	24	usa	usa	PROPN
bjp-23039	33	25	)	)	PUNCT
bjp-23039	33	26	.	.	PUNCT
bjp-23039	34	1	briefly	briefly	NOUN
bjp-23039	34	2	,	,	PUNCT
bjp-23039	34	3	cells	cell	NOUN
bjp-23039	34	4	at	at	ADP
bjp-23039	34	5	a	a	DET
bjp-23039	34	6	density	density	NOUN
bjp-23039	34	7	of	of	ADP
bjp-23039	34	8	3	3	NUM
bjp-23039	34	9	-	-	SYM
bjp-23039	34	10	7	7	NUM
bjp-23039	34	11	×	×	NOUN
bjp-23039	34	12	103	103	NUM
bjp-23039	34	13	were	be	AUX
bjp-23039	34	14	seeded	seed	VERB
bjp-23039	34	15	per	per	ADP
bjp-23039	34	16	well	well	ADV
bjp-23039	34	17	in	in	ADP
bjp-23039	34	18	96	96	NUM
bjp-23039	34	19	-	-	PUNCT
bjp-23039	34	20	well	well	NOUN
bjp-23039	34	21	plates	plate	NOUN
bjp-23039	34	22	.	.	PUNCT
bjp-23039	35	1	after	after	ADP
bjp-23039	35	2	12	12	NUM
bjp-23039	35	3	hours	hour	NOUN
bjp-23039	35	4	of	of	ADP
bjp-23039	35	5	incubation	incubation	NOUN
bjp-23039	35	6	at	at	ADP
bjp-23039	35	7	37	37	NUM
bjp-23039	35	8	°	°	NOUN
bjp-23039	35	9	c	c	NOUN
bjp-23039	35	10	,	,	PUNCT
bjp-23039	35	11	the	the	DET
bjp-23039	35	12	cells	cell	NOUN
bjp-23039	35	13	were	be	AUX
bjp-23039	35	14	treated	treat	VERB
bjp-23039	35	15	with	with	ADP
bjp-23039	35	16	various	various	ADJ
bjp-23039	35	17	concentrations	concentration	NOUN
bjp-23039	35	18	of	of	ADP
bjp-23039	35	19	fisetin	fisetin	NOUN
bjp-23039	35	20	(	(	PUNCT
bjp-23039	35	21	20	20	NUM
bjp-23039	35	22	-	-	SYM
bjp-23039	35	23	100	100	NUM
bjp-23039	35	24	μm	μm	NUM
bjp-23039	35	25	)	)	PUNCT
bjp-23039	35	26	for	for	ADP
bjp-23039	35	27	12	12	NUM
bjp-23039	35	28	,	,	PUNCT
bjp-23039	35	29	24	24	NUM
bjp-23039	35	30	or	or	CCONJ
bjp-23039	35	31	48	48	NUM
bjp-23039	35	32	hours	hour	NOUN
bjp-23039	35	33	.	.	PUNCT
bjp-23039	36	1	the	the	DET
bjp-23039	36	2	cells	cell	NOUN
bjp-23039	36	3	were	be	AUX
bjp-23039	36	4	further	far	ADV
bjp-23039	36	5	incubated	incubate	VERB
bjp-23039	36	6	with	with	ADP
bjp-23039	36	7	mts	mts	NOUN
bjp-23039	36	8	[	[	PUNCT
bjp-23039	36	9	3-(4,5	3-(4,5	PROPN
bjp-23039	36	10	-	-	PUNCT
bjp-23039	36	11	dimethylthiazol-2	dimethylthiazol-2	VERB
bjp-23039	36	12	-	-	PUNCT
bjp-23039	36	13	yl)-5-(3	yl)-5-(3	NOUN
bjp-23039	36	14	-	-	PUNCT
bjp-23039	36	15	carboxymethoxyphenyl)-2-(4	carboxymethoxyphenyl)-2-(4	NOUN
bjp-23039	36	16	-	-	PUNCT
bjp-23039	36	17	sulfophenyl)-2h	sulfophenyl)-2h	NOUN
bjp-23039	36	18	-	-	PUNCT
bjp-23039	36	19	tetrazolium	tetrazolium	NOUN
bjp-23039	36	20	]	]	PUNCT
bjp-23039	36	21	and	and	CCONJ
bjp-23039	36	22	phenazine	phenazine	NOUN
bjp-23039	36	23	methosulfate	methosulfate	NOUN
bjp-23039	36	24	(	(	PUNCT
bjp-23039	36	25	pms	pm	NOUN
bjp-23039	36	26	)	)	PUNCT
bjp-23039	36	27	for	for	ADP
bjp-23039	36	28	2	2	NUM
bjp-23039	36	29	-	-	SYM
bjp-23039	36	30	4	4	NUM
bjp-23039	36	31	hours	hour	NOUN
bjp-23039	36	32	at	at	ADP
bjp-23039	36	33	37	37	NUM
bjp-23039	36	34	°	°	ADP
bjp-23039	36	35	c	c	NOUN
bjp-23039	36	36	as	as	ADP
bjp-23039	36	37	per	per	ADP
bjp-23039	36	38	manufacturer	manufacturer	NOUN
bjp-23039	36	39	’s	’s	PART
bjp-23039	36	40	instructions	instruction	NOUN
bjp-23039	36	41	.	.	PUNCT
bjp-23039	37	1	the	the	DET
bjp-23039	37	2	color	color	NOUN
bjp-23039	37	3	developed	develop	VERB
bjp-23039	37	4	was	be	AUX
bjp-23039	37	5	read	read	VERB
bjp-23039	37	6	at	at	ADP
bjp-23039	37	7	490	490	NUM
bjp-23039	37	8	nm	nm	NOUN
bjp-23039	37	9	using	use	VERB
bjp-23039	37	10	a	a	DET
bjp-23039	37	11	mr7000	mr7000	ADJ
bjp-23039	37	12	microplate	microplate	NOUN
bjp-23039	37	13	reader	reader	NOUN
bjp-23039	37	14	(	(	PUNCT
bjp-23039	37	15	dynatech	dynatech	PROPN
bjp-23039	37	16	,	,	PUNCT
bjp-23039	37	17	usa	usa	PROPN
bjp-23039	37	18	)	)	PUNCT
bjp-23039	37	19	.	.	PUNCT
bjp-23039	38	1	analysis	analysis	NOUN
bjp-23039	38	2	of	of	ADP
bjp-23039	38	3	apoptosis	apoptosis	NOUN
bjp-23039	38	4	by	by	ADP
bjp-23039	38	5	annexin	annexin	NOUN
bjp-23039	38	6	v	v	ADP
bjp-23039	38	7	assay	assay	NOUN
bjp-23039	38	8	following	follow	VERB
bjp-23039	38	9	incubation	incubation	NOUN
bjp-23039	38	10	with	with	ADP
bjp-23039	38	11	various	various	ADJ
bjp-23039	38	12	concentrations	concentration	NOUN
bjp-23039	38	13	of	of	ADP
bjp-23039	38	14	fisetin	fisetin	NOUN
bjp-23039	38	15	(	(	PUNCT
bjp-23039	38	16	20	20	NUM
bjp-23039	38	17	-	-	SYM
bjp-23039	38	18	100	100	NUM
bjp-23039	38	19	µm	µm	NOUN
bjp-23039	38	20	)	)	PUNCT
bjp-23039	38	21	for	for	ADP
bjp-23039	38	22	24	24	NUM
bjp-23039	38	23	and	and	CCONJ
bjp-23039	38	24	48	48	NUM
bjp-23039	38	25	hours	hour	NOUN
bjp-23039	38	26	,	,	PUNCT
bjp-23039	38	27	cells	cell	NOUN
bjp-23039	38	28	were	be	AUX
bjp-23039	38	29	trypsinized	trypsinize	VERB
bjp-23039	38	30	and	and	CCONJ
bjp-23039	38	31	collected	collect	VERB
bjp-23039	38	32	for	for	ADP
bjp-23039	38	33	detection	detection	NOUN
bjp-23039	38	34	of	of	ADP
bjp-23039	38	35	apoptosis	apoptosis	NOUN
bjp-23039	38	36	using	use	VERB
bjp-23039	38	37	annexin	annexin	NOUN
bjp-23039	38	38	v	v	NOUN
bjp-23039	38	39	-	-	PUNCT
bjp-23039	38	40	fitc	fitc	NOUN
bjp-23039	38	41	(	(	PUNCT
bjp-23039	38	42	fluorescein	fluorescein	NOUN
bjp-23039	38	43	isothiocyanate	isothiocyanate	NOUN
bjp-23039	38	44	)	)	PUNCT
bjp-23039	38	45	apoptosis	apoptosis	NOUN
bjp-23039	38	46	detection	detection	NOUN
bjp-23039	38	47	kit	kit	NOUN
bjp-23039	38	48	(	(	PUNCT
bjp-23039	38	49	santa	santa	PROPN
bjp-23039	38	50	cruz	cruz	PROPN
bjp-23039	38	51	biotechnology	biotechnology	PROPN
bjp-23039	38	52	,	,	PUNCT
bjp-23039	38	53	usa	usa	PROPN
bjp-23039	38	54	)	)	PUNCT
bjp-23039	38	55	.	.	PUNCT
bjp-23039	39	1	briefly	briefly	NOUN
bjp-23039	39	2	,	,	PUNCT
bjp-23039	39	3	1	1	NUM
bjp-23039	39	4	×	×	NOUN
bjp-23039	39	5	106	106	NUM
bjp-23039	39	6	cells	cell	NOUN
bjp-23039	39	7	treated	treat	VERB
bjp-23039	39	8	with	with	ADP
bjp-23039	39	9	fisetin	fisetin	NOUN
bjp-23039	39	10	were	be	AUX
bjp-23039	39	11	subjected	subject	VERB
bjp-23039	39	12	to	to	ADP
bjp-23039	39	13	annexin	annexin	NOUN
bjp-23039	39	14	v	v	ADP
bjp-23039	39	15	staining	stain	VERB
bjp-23039	39	16	.	.	PUNCT
bjp-23039	40	1	the	the	DET
bjp-23039	40	2	cells	cell	NOUN
bjp-23039	40	3	were	be	AUX
bjp-23039	40	4	washed	wash	VERB
bjp-23039	40	5	in	in	ADP
bjp-23039	40	6	pbs	pbs	PROPN
bjp-23039	40	7	and	and	CCONJ
bjp-23039	40	8	resuspended	resuspend	VERB
bjp-23039	40	9	in	in	ADP
bjp-23039	40	10	binding	bind	VERB
bjp-23039	40	11	buffer	buffer	NOUN
bjp-23039	40	12	containing	contain	VERB
bjp-23039	40	13	(	(	PUNCT
bjp-23039	40	14	100	100	NUM
bjp-23039	40	15	μl	μl	PRON
bjp-23039	40	16	)	)	PUNCT
bjp-23039	40	17	fitc	fitc	NOUN
bjp-23039	40	18	-	-	PUNCT
bjp-23039	40	19	conjugated	conjugate	VERB
bjp-23039	40	20	anti	anti	ADJ
bjp-23039	40	21	-	-	ADJ
bjp-23039	40	22	annexin	annexin	NOUN
bjp-23039	40	23	v	v	ADP
bjp-23039	40	24	antibody	antibody	NOUN
bjp-23039	40	25	and	and	CCONJ
bjp-23039	40	26	analyzed	analyze	VERB
bjp-23039	40	27	for	for	ADP
bjp-23039	40	28	flurosence	flurosence	NOUN
bjp-23039	40	29	using	use	VERB
bjp-23039	40	30	a	a	DET
bjp-23039	40	31	flow	flow	NOUN
bjp-23039	40	32	cytometer	cytometer	NOUN
bjp-23039	40	33	(	(	PUNCT
bjp-23039	40	34	facs	facs	PROPN
bjp-23039	40	35	calibur	calibur	PROPN
bjp-23039	40	36	,	,	PUNCT
bjp-23039	40	37	bd	bd	PROPN
bjp-23039	40	38	biosciences	bioscience	NOUN
bjp-23039	40	39	)	)	PUNCT
bjp-23039	40	40	.	.	PUNCT
bjp-23039	41	1	measurement	measurement	NOUN
bjp-23039	41	2	of	of	ADP
bjp-23039	41	3	mitochondrial	mitochondrial	ADJ
bjp-23039	41	4	membrane	membrane	NOUN
bjp-23039	41	5	potential	potential	NOUN
bjp-23039	41	6	the	the	DET
bjp-23039	41	7	mitochondrial	mitochondrial	ADJ
bjp-23039	41	8	membrane	membrane	NOUN
bjp-23039	41	9	potential	potential	NOUN
bjp-23039	41	10	(	(	PUNCT
bjp-23039	41	11	mmp	mmp	PROPN
bjp-23039	41	12	)	)	PUNCT
bjp-23039	41	13	was	be	AUX
bjp-23039	41	14	measured	measure	VERB
bjp-23039	41	15	with	with	ADP
bjp-23039	41	16	jc-1	jc-1	NOUN
bjp-23039	41	17	fluorescent	fluorescent	NOUN
bjp-23039	41	18	probe	probe	NOUN
bjp-23039	41	19	(	(	PUNCT
bjp-23039	41	20	cayman	cayman	NOUN
bjp-23039	41	21	chemical	chemical	PROPN
bjp-23039	41	22	)	)	PUNCT
bjp-23039	41	23	.	.	PUNCT
bjp-23039	42	1	in	in	ADP
bjp-23039	42	2	brief	brief	ADJ
bjp-23039	42	3	,	,	PUNCT
bjp-23039	42	4	2	2	NUM
bjp-23039	42	5	×	×	NOUN
bjp-23039	42	6	105	105	NUM
bjp-23039	42	7	cells	cell	NOUN
bjp-23039	42	8	exposed	expose	VERB
bjp-23039	42	9	to	to	PART
bjp-23039	42	10	fisetin	fisetin	VERB
bjp-23039	42	11	(	(	PUNCT
bjp-23039	42	12	20	20	NUM
bjp-23039	42	13	100	100	NUM
bjp-23039	42	14	μm	μm	NUM
bjp-23039	42	15	)	)	PUNCT
bjp-23039	42	16	for	for	ADP
bjp-23039	42	17	24	24	NUM
bjp-23039	42	18	hours	hour	NOUN
bjp-23039	42	19	were	be	AUX
bjp-23039	42	20	incubated	incubate	VERB
bjp-23039	42	21	with	with	ADP
bjp-23039	42	22	jc-1	jc-1	NOUN
bjp-23039	42	23	for	for	ADP
bjp-23039	42	24	20	20	NUM
bjp-23039	42	25	min	min	NOUN
bjp-23039	42	26	at	at	ADP
bjp-23039	42	27	37	37	NUM
bjp-23039	42	28	°	°	NOUN
bjp-23039	42	29	c	c	NOUN
bjp-23039	42	30	.	.	PUNCT
bjp-23039	43	1	the	the	DET
bjp-23039	43	2	stained	stained	ADJ
bjp-23039	43	3	cells	cell	NOUN
bjp-23039	43	4	were	be	AUX
bjp-23039	43	5	washed	wash	VERB
bjp-23039	43	6	twice	twice	ADV
bjp-23039	43	7	with	with	ADP
bjp-23039	43	8	pbs	pb	NOUN
bjp-23039	43	9	and	and	CCONJ
bjp-23039	43	10	analyzed	analyze	VERB
bjp-23039	43	11	by	by	ADP
bjp-23039	43	12	a	a	DET
bjp-23039	43	13	flow	flow	NOUN
bjp-23039	43	14	cytometer	cytometer	NOUN
bjp-23039	43	15	.	.	PUNCT
bjp-23039	44	1	mitochondrial	mitochondrial	ADJ
bjp-23039	44	2	depolarization	depolarization	NOUN
bjp-23039	44	3	was	be	AUX
bjp-23039	44	4	indicated	indicate	VERB
bjp-23039	44	5	by	by	ADP
bjp-23039	44	6	a	a	DET
bjp-23039	44	7	decrease	decrease	NOUN
bjp-23039	44	8	in	in	ADP
bjp-23039	44	9	the	the	DET
bjp-23039	44	10	red/	red/	PROPN
bjp-23039	44	11	green	green	ADJ
bjp-23039	44	12	fluorescence	fluorescence	NOUN
bjp-23039	44	13	intensity	intensity	NOUN
bjp-23039	44	14	ratio	ratio	NOUN
bjp-23039	44	15	.	.	PUNCT
bjp-23039	45	1	measurement	measurement	NOUN
bjp-23039	45	2	of	of	ADP
bjp-23039	45	3	ros	ros	PROPN
bjp-23039	45	4	generation	generation	NOUN
bjp-23039	45	5	of	of	ADP
bjp-23039	45	6	intracellular	intracellular	ADJ
bjp-23039	45	7	ros	ro	NOUN
bjp-23039	45	8	was	be	AUX
bjp-23039	45	9	measured	measure	VERB
bjp-23039	45	10	using	use	VERB
bjp-23039	45	11	2',7'-dichlorofluorescin	2',7'-dichlorofluorescin	NUM
bjp-23039	45	12	diacetate	diacetate	NOUN
bjp-23039	45	13	(	(	PUNCT
bjp-23039	45	14	dcfh	dcfh	NOUN
bjp-23039	45	15	-	-	PUNCT
bjp-23039	45	16	da	da	NOUN
bjp-23039	45	17	)	)	PUNCT
bjp-23039	45	18	(	(	PUNCT
bjp-23039	45	19	beyotime	beyotime	NOUN
bjp-23039	45	20	)	)	PUNCT
bjp-23039	45	21	.	.	PUNCT
bjp-23039	46	1	briefly	briefly	NOUN
bjp-23039	46	2	,	,	PUNCT
bjp-23039	46	3	2	2	NUM
bjp-23039	46	4	x	x	SYM
bjp-23039	46	5	105	105	NUM
bjp-23039	46	6	cells	cell	NOUN
bjp-23039	46	7	were	be	AUX
bjp-23039	46	8	plated	plate	VERB
bjp-23039	46	9	in	in	ADP
bjp-23039	46	10	each	each	DET
bjp-23039	46	11	well	well	NOUN
bjp-23039	46	12	of	of	ADP
bjp-23039	46	13	six	six	NUM
bjp-23039	46	14	-	-	PUNCT
bjp-23039	46	15	well	well	NOUN
bjp-23039	46	16	plates	plate	NOUN
bjp-23039	46	17	.	.	PUNCT
bjp-23039	47	1	following	follow	VERB
bjp-23039	47	2	incubation	incubation	NOUN
bjp-23039	47	3	with	with	ADP
bjp-23039	47	4	various	various	ADJ
bjp-23039	47	5	concentrations	concentration	NOUN
bjp-23039	47	6	of	of	ADP
bjp-23039	47	7	fisetin	fisetin	NOUN
bjp-23039	47	8	(	(	PUNCT
bjp-23039	47	9	20	20	NUM
bjp-23039	47	10	-	-	SYM
bjp-23039	47	11	100	100	NUM
bjp-23039	47	12	μm	μm	NUM
bjp-23039	47	13	)	)	PUNCT
bjp-23039	47	14	for	for	ADP
bjp-23039	47	15	12	12	NUM
bjp-23039	47	16	hours	hour	NOUN
bjp-23039	47	17	and	and	CCONJ
bjp-23039	47	18	24	24	NUM
bjp-23039	47	19	hours	hour	NOUN
bjp-23039	47	20	,	,	PUNCT
bjp-23039	47	21	cells	cell	NOUN
bjp-23039	47	22	were	be	AUX
bjp-23039	47	23	incubated	incubate	VERB
bjp-23039	47	24	with	with	ADP
bjp-23039	47	25	dcfh	dcfh	NOUN
bjp-23039	47	26	-	-	PUNCT
bjp-23039	47	27	da	da	NOUN
bjp-23039	47	28	(	(	PUNCT
bjp-23039	47	29	10	10	NUM
bjp-23039	47	30	μm	μm	NUM
bjp-23039	47	31	)	)	PUNCT
bjp-23039	47	32	for	for	ADP
bjp-23039	47	33	30	30	NUM
bjp-23039	47	34	min	min	NOUN
bjp-23039	47	35	at	at	ADP
bjp-23039	47	36	37	37	NUM
bjp-23039	47	37	°	°	NOUN
bjp-23039	47	38	c	c	NOUN
bjp-23039	47	39	.	.	PUNCT
bjp-23039	48	1	the	the	DET
bjp-23039	48	2	level	level	NOUN
bjp-23039	48	3	of	of	ADP
bjp-23039	48	4	ros	ros	PROPN
bjp-23039	48	5	was	be	AUX
bjp-23039	48	6	determined	determine	VERB
bjp-23039	48	7	by	by	ADP
bjp-23039	48	8	fluorescence	fluorescence	NOUN
bjp-23039	48	9	microscopy	microscopy	NOUN
bjp-23039	48	10	and	and	CCONJ
bjp-23039	48	11	flow	flow	NOUN
bjp-23039	48	12	cytometer	cytometer	NOUN
bjp-23039	48	13	(	(	PUNCT
bjp-23039	48	14	facs	facs	PROPN
bjp-23039	48	15	calibur	calibur	PROPN
bjp-23039	48	16	,	,	PUNCT
bjp-23039	48	17	bd	bd	PROPN
bjp-23039	48	18	biosciences	bioscience	NOUN
bjp-23039	48	19	)	)	PUNCT
bjp-23039	48	20	.	.	PUNCT
bjp-23039	49	1	western	western	ADJ
bjp-23039	49	2	blotting	blot	VERB
bjp-23039	49	3	the	the	DET
bjp-23039	49	4	u-2	u-2	PROPN
bjp-23039	49	5	os	os	PROPN
bjp-23039	49	6	were	be	AUX
bjp-23039	49	7	seeded	seed	VERB
bjp-23039	49	8	at	at	ADP
bjp-23039	49	9	a	a	DET
bjp-23039	49	10	density	density	NOUN
bjp-23039	49	11	of	of	ADP
bjp-23039	49	12	5	5	NUM
bjp-23039	49	13	×	×	NOUN
bjp-23039	49	14	105	105	NUM
bjp-23039	49	15	cells	cell	NOUN
bjp-23039	49	16	in	in	ADP
bjp-23039	49	17	60	60	NUM
bjp-23039	49	18	-	-	PUNCT
bjp-23039	49	19	mm	mm	NOUN
bjp-23039	49	20	dishes	dish	NOUN
bjp-23039	49	21	and	and	CCONJ
bjp-23039	49	22	exposed	expose	VERB
bjp-23039	49	23	to	to	PART
bjp-23039	49	24	fisetin	fisetin	VERB
bjp-23039	49	25	(	(	PUNCT
bjp-23039	49	26	20	20	NUM
bjp-23039	49	27	100	100	NUM
bjp-23039	49	28	µm	µm	NOUN
bjp-23039	49	29	)	)	PUNCT
bjp-23039	49	30	for	for	ADP
bjp-23039	49	31	24	24	NUM
bjp-23039	49	32	hours	hour	NOUN
bjp-23039	49	33	.	.	PUNCT
bjp-23039	50	1	the	the	DET
bjp-23039	50	2	cells	cell	NOUN
bjp-23039	50	3	were	be	AUX
bjp-23039	50	4	collected	collect	VERB
bjp-23039	50	5	by	by	ADP
bjp-23039	50	6	centrifugation	centrifugation	NOUN
bjp-23039	50	7	and	and	CCONJ
bjp-23039	50	8	the	the	DET
bjp-23039	50	9	pellets	pellet	NOUN
bjp-23039	50	10	were	be	AUX
bjp-23039	50	11	lysed	lyse	VERB
bjp-23039	50	12	in	in	ADP
bjp-23039	50	13	ripa	ripa	ADJ
bjp-23039	50	14	lysis	lysis	NOUN
bjp-23039	50	15	buffer	buffer	NOUN
bjp-23039	50	16	containing	contain	VERB
bjp-23039	50	17	protease	protease	NOUN
bjp-23039	50	18	inhibitor	inhibitor	NOUN
bjp-23039	50	19	cocktail	cocktail	NOUN
bjp-23039	50	20	for	for	ADP
bjp-23039	50	21	30	30	NUM
bjp-23039	50	22	min	min	NOUN
bjp-23039	50	23	on	on	ADP
bjp-23039	50	24	ice	ice	NOUN
bjp-23039	50	25	.	.	PUNCT
bjp-23039	51	1	to	to	PART
bjp-23039	51	2	determine	determine	VERB
bjp-23039	51	3	the	the	DET
bjp-23039	51	4	cytoplasmic	cytoplasmic	ADJ
bjp-23039	51	5	ikb	ikb	PROPN
bjp-23039	51	6	,	,	PUNCT
bjp-23039	51	7	cytoplasmic	cytoplasmic	ADJ
bjp-23039	51	8	extracts	extract	NOUN
bjp-23039	51	9	were	be	AUX
bjp-23039	51	10	prepared	prepare	VERB
bjp-23039	51	11	(	(	PUNCT
bjp-23039	51	12	lee	lee	PROPN
bjp-23039	51	13	et	et	PROPN
bjp-23039	51	14	al	al	PROPN
bjp-23039	51	15	.	.	PROPN
bjp-23039	51	16	,	,	PUNCT
bjp-23039	51	17	2006	2006	NUM
bjp-23039	51	18	)	)	PUNCT
bjp-23039	51	19	.	.	PUNCT
bjp-23039	52	1	to	to	PART
bjp-23039	52	2	analyze	analyze	VERB
bjp-23039	52	3	nf	nf	NOUN
bjp-23039	52	4	-	-	PUNCT
bjp-23039	52	5	kb	kb	NOUN
bjp-23039	52	6	(	(	PUNCT
bjp-23039	52	7	p65	p65	NOUN
bjp-23039	52	8	)	)	PUNCT
bjp-23039	52	9	,	,	PUNCT
bjp-23039	52	10	nuclear	nuclear	ADJ
bjp-23039	52	11	extract	extract	NOUN
bjp-23039	52	12	was	be	AUX
bjp-23039	52	13	prepared	prepare	VERB
bjp-23039	52	14	using	use	VERB
bjp-23039	52	15	a	a	DET
bjp-23039	52	16	previously	previously	ADV
bjp-23039	52	17	described	describe	VERB
bjp-23039	52	18	method	method	NOUN
bjp-23039	52	19	(	(	PUNCT
bjp-23039	52	20	lee	lee	PROPN
bjp-23039	52	21	et	et	PROPN
bjp-23039	52	22	al	al	PROPN
bjp-23039	52	23	.	.	PROPN
bjp-23039	52	24	,	,	PUNCT
bjp-23039	52	25	2006	2006	NUM
bjp-23039	52	26	)	)	PUNCT
bjp-23039	52	27	.	.	PUNCT
bjp-23039	53	1	protein	protein	NOUN
bjp-23039	53	2	concentration	concentration	NOUN
bjp-23039	53	3	was	be	AUX
bjp-23039	53	4	determined	determine	VERB
bjp-23039	53	5	by	by	ADP
bjp-23039	53	6	bio	bio	PROPN
bjp-23039	53	7	-	-	ADJ
bjp-23039	53	8	rad	rad	ADJ
bjp-23039	53	9	protein	protein	NOUN
bjp-23039	53	10	assay	assay	NOUN
bjp-23039	53	11	kit	kit	NOUN
bjp-23039	53	12	(	(	PUNCT
bjp-23039	53	13	biorad	biorad	NOUN
bjp-23039	53	14	laboratories	laboratory	NOUN
bjp-23039	53	15	,	,	PUNCT
bjp-23039	53	16	usa	usa	PROPN
bjp-23039	53	17	)	)	PUNCT
bjp-23039	53	18	.	.	PUNCT
bjp-23039	54	1	proteins	protein	NOUN
bjp-23039	54	2	were	be	AUX
bjp-23039	54	3	then	then	ADV
bjp-23039	54	4	separated	separate	VERB
bjp-23039	54	5	by	by	ADP
bjp-23039	54	6	sds	sds	PROPN
bjp-23039	54	7	-	-	PUNCT
bjp-23039	54	8	page	page	NOUN
bjp-23039	54	9	,	,	PUNCT
bjp-23039	54	10	electro	electro	NOUN
bjp-23039	54	11	-	-	PUNCT
bjp-23039	54	12	transferred	transfer	VERB
bjp-23039	54	13	to	to	ADP
bjp-23039	54	14	nitrocellulose	nitrocellulose	NOUN
bjp-23039	54	15	membranes	membrane	NOUN
bjp-23039	54	16	,	,	PUNCT
bjp-23039	54	17	blotted	blot	VERB
bjp-23039	54	18	with	with	ADP
bjp-23039	54	19	respective	respective	ADJ
bjp-23039	54	20	antibodies	antibody	NOUN
bjp-23039	54	21	(	(	PUNCT
bjp-23039	54	22	cleaved	cleaved	NOUN
bjp-23039	54	23	caspase-3	caspase-3	PROPN
bjp-23039	54	24	,	,	PUNCT
bjp-23039	54	25	cleaved	cleaved	ADJ
bjp-23039	54	26	caspase-8	caspase-8	PROPN
bjp-23039	54	27	,	,	PUNCT
bjp-23039	54	28	cleaved	cleaved	PROPN
bjp-23039	54	29	caspase-9	caspase-9	PROPN
bjp-23039	54	30	,	,	PUNCT
bjp-23039	54	31	erk1/2	erk1/2	PROPN
bjp-23039	54	32	,	,	PUNCT
bjp-23039	54	33	p	p	NOUN
bjp-23039	54	34	-	-	PUNCT
bjp-23039	54	35	erk1/2	erk1/2	NOUN
bjp-23039	54	36	,	,	PUNCT
bjp-23039	54	37	p-38	p-38	NOUN
bjp-23039	54	38	,	,	PUNCT
bjp-23039	54	39	p	p	NOUN
bjp-23039	54	40	-	-	PUNCT
bjp-23039	54	41	p38	p38	NOUN
bjp-23039	54	42	,	,	PUNCT
bjp-23039	54	43	jnk	jnk	PROPN
bjp-23039	54	44	,	,	PUNCT
bjp-23039	54	45	p	p	PROPN
bjp-23039	54	46	-	-	PUNCT
bjp-23039	54	47	jnk	jnk	NOUN
bjp-23039	54	48	,	,	PUNCT
bjp-23039	54	49	c	c	PROPN
bjp-23039	54	50	-	-	PUNCT
bjp-23039	54	51	jun	jun	PROPN
bjp-23039	54	52	,	,	PUNCT
bjp-23039	54	53	p	p	PROPN
bjp-23039	54	54	-	-	PUNCT
bjp-23039	54	55	c	c	NOUN
bjp-23039	54	56	-jun	-jun	PROPN
bjp-23039	54	57	,	,	PUNCT
bjp-23039	54	58	akt	akt	PROPN
bjp-23039	54	59	,	,	PUNCT
bjp-23039	54	60	phospho	phospho	NOUN
bjp-23039	54	61	-	-	PUNCT
bjp-23039	54	62	akt	akt	NOUN
bjp-23039	54	63	,	,	PUNCT
bjp-23039	54	64	gsk3β	gsk3β	PROPN
bjp-23039	54	65	,	,	PUNCT
bjp-23039	54	66	phospho	phospho	NOUN
bjp-23039	54	67	-	-	PUNCT
bjp-23039	54	68	gsk3β	gsk3β	PROPN
bjp-23039	54	69	,	,	PUNCT
bjp-23039	54	70	nfkb	nfkb	PROPN
bjp-23039	54	71	(	(	PUNCT
bjp-23039	54	72	p65	p65	NOUN
bjp-23039	54	73	)	)	PUNCT
bjp-23039	54	74	,	,	PUNCT
bjp-23039	54	75	ikbα	ikbα	NOUN
bjp-23039	54	76	,	,	PUNCT
bjp-23039	54	77	bcl	bcl	PROPN
bjp-23039	54	78	-	-	PROPN
bjp-23039	54	79	xl	xl	PROPN
bjp-23039	54	80	,	,	PUNCT
bjp-23039	54	81	bcl-2	bcl-2	ADJ
bjp-23039	54	82	,	,	PUNCT
bjp-23039	54	83	bad	bad	ADJ
bjp-23039	54	84	,	,	PUNCT
bjp-23039	54	85	bax	bax	PROPN
bjp-23039	54	86	,	,	PUNCT
bjp-23039	54	87	mtorc1	mtorc1	NOUN
bjp-23039	54	88	,	,	PUNCT
bjp-23039	54	89	cyclind1	cyclind1	NOUN
bjp-23039	54	90	,	,	PUNCT
bjp-23039	54	91	pten	pten	VERB
bjp-23039	54	92	and	and	CCONJ
bjp-23039	54	93	β	β	NOUN
bjp-23039	54	94	-	-	NOUN
bjp-23039	54	95	actin	actin	NOUN
bjp-23039	54	96	)	)	PUNCT
bjp-23039	54	97	.	.	PUNCT
bjp-23039	55	1	the	the	DET
bjp-23039	55	2	immunoreactive	immunoreactive	ADJ
bjp-23039	55	3	bands	band	NOUN
bjp-23039	55	4	were	be	AUX
bjp-23039	55	5	detected	detect	VERB
bjp-23039	55	6	by	by	ADP
bjp-23039	55	7	enhanced	enhanced	ADJ
bjp-23039	55	8	chemiluminescence	chemiluminescence	NOUN
bjp-23039	55	9	(	(	PUNCT
bjp-23039	55	10	ge	ge	PROPN
bjp-23039	55	11	healthcare	healthcare	PROPN
bjp-23039	55	12	)	)	PUNCT
bjp-23039	55	13	.	.	PUNCT
bjp-23039	56	1	statistical	statistical	ADJ
bjp-23039	56	2	analysis	analysis	NOUN
bjp-23039	56	3	the	the	DET
bjp-23039	56	4	data	datum	NOUN
bjp-23039	56	5	are	be	AUX
bjp-23039	56	6	presented	present	VERB
bjp-23039	56	7	as	as	SCONJ
bjp-23039	56	8	means	mean	NOUN
bjp-23039	56	9	±	±	NUM
bjp-23039	56	10	sd	sd	PROPN
bjp-23039	56	11	obtained	obtain	VERB
bjp-23039	56	12	from	from	ADP
bjp-23039	56	13	three	three	NUM
bjp-23039	56	14	or	or	CCONJ
bjp-23039	56	15	six	six	NUM
bjp-23039	56	16	individual	individual	ADJ
bjp-23039	56	17	experiments	experiment	NOUN
bjp-23039	56	18	.	.	PUNCT
bjp-23039	57	1	the	the	DET
bjp-23039	57	2	values	value	NOUN
bjp-23039	57	3	were	be	AUX
bjp-23039	57	4	analysed	analyse	VERB
bjp-23039	57	5	by	by	ADP
bjp-23039	57	6	one	one	NUM
bjp-23039	57	7	-	-	PUNCT
bjp-23039	57	8	way	way	NOUN
bjp-23039	57	9	anova	anova	X
bjp-23039	57	10	(	(	PUNCT
bjp-23039	57	11	analysis	analysis	NOUN
bjp-23039	57	12	of	of	ADP
bjp-23039	57	13	variance	variance	NOUN
bjp-23039	57	14	)	)	PUNCT
bjp-23039	57	15	.	.	PUNCT
bjp-23039	58	1	bangladesh	bangladesh	PROPN
bjp-23039	58	2	j	j	PROPN
bjp-23039	58	3	pharmacol	pharmacol	PROPN
bjp-23039	58	4	2015	2015	NUM
bjp-23039	58	5	;	;	PUNCT
bjp-23039	58	6	10	10	NUM
bjp-23039	58	7	:	:	SYM
bjp-23039	58	8	820	820	NUM
bjp-23039	58	9	-	-	SYM
bjp-23039	58	10	829	829	NUM
bjp-23039	58	11	821	821	NUM
bjp-23039	58	12	all	all	DET
bjp-23039	58	13	statistical	statistical	ADJ
bjp-23039	58	14	analyses	analysis	NOUN
bjp-23039	58	15	were	be	AUX
bjp-23039	58	16	performed	perform	VERB
bjp-23039	58	17	using	use	VERB
bjp-23039	58	18	the	the	DET
bjp-23039	58	19	spss	spss	PROPN
bjp-23039	58	20	software	software	NOUN
bjp-23039	58	21	(	(	PUNCT
bjp-23039	58	22	version	version	NOUN
bjp-23039	58	23	17.0	17.0	NUM
bjp-23039	58	24	,	,	PUNCT
bjp-23039	58	25	spss	spss	PROPN
bjp-23039	58	26	,	,	PUNCT
bjp-23039	58	27	usa	usa	PROPN
bjp-23039	58	28	)	)	PUNCT
bjp-23039	58	29	.	.	PUNCT
bjp-23039	59	1	results	result	NOUN
bjp-23039	59	2	fisetin	fisetin	VERB
bjp-23039	59	3	induces	induce	VERB
bjp-23039	59	4	apoptosis	apoptosis	NOUN
bjp-23039	59	5	of	of	ADP
bjp-23039	59	6	osteosarcoma	osteosarcoma	ADJ
bjp-23039	59	7	cells	cell	NOUN
bjp-23039	59	8	u-2	u-2	PROPN
bjp-23039	59	9	os	os	PROPN
bjp-23039	59	10	osteosarcoma	osteosarcoma	ADJ
bjp-23039	59	11	cancer	cancer	NOUN
bjp-23039	59	12	cells	cell	NOUN
bjp-23039	59	13	exposed	expose	VERB
bjp-23039	59	14	to	to	PART
bjp-23039	59	15	fisetin	fisetin	VERB
bjp-23039	59	16	showed	show	VERB
bjp-23039	59	17	considerable	considerable	ADJ
bjp-23039	59	18	susceptibility	susceptibility	NOUN
bjp-23039	59	19	to	to	ADP
bjp-23039	59	20	different	different	ADJ
bjp-23039	59	21	concentrations	concentration	NOUN
bjp-23039	59	22	.	.	PUNCT
bjp-23039	60	1	the	the	DET
bjp-23039	60	2	cell	cell	NOUN
bjp-23039	60	3	viability	viability	NOUN
bjp-23039	60	4	gradually	gradually	ADV
bjp-23039	60	5	decreased	decrease	VERB
bjp-23039	60	6	in	in	ADP
bjp-23039	60	7	a	a	DET
bjp-23039	60	8	concentration	concentration	NOUN
bjp-23039	60	9	and	and	CCONJ
bjp-23039	60	10	time	time	NOUN
bjp-23039	60	11	-	-	PUNCT
bjp-23039	60	12	dependent	dependent	ADJ
bjp-23039	60	13	manner	manner	NOUN
bjp-23039	60	14	.	.	PUNCT
bjp-23039	61	1	treatment	treatment	NOUN
bjp-23039	61	2	with	with	ADP
bjp-23039	61	3	fisetin	fisetin	NOUN
bjp-23039	61	4	at	at	ADP
bjp-23039	61	5	80	80	NUM
bjp-23039	61	6	and	and	CCONJ
bjp-23039	61	7	100	100	NUM
bjp-23039	61	8	µm	µm	NUM
bjp-23039	61	9	presented	present	VERB
bjp-23039	61	10	more	more	ADV
bjp-23039	61	11	pronounced	pronounce	VERB
bjp-23039	61	12	decreases	decrease	NOUN
bjp-23039	61	13	in	in	ADP
bjp-23039	61	14	cell	cell	NOUN
bjp-23039	61	15	viability	viability	NOUN
bjp-23039	61	16	than	than	ADP
bjp-23039	61	17	lower	low	ADJ
bjp-23039	61	18	doses	dose	NOUN
bjp-23039	61	19	(	(	PUNCT
bjp-23039	61	20	figure	figure	NOUN
bjp-23039	61	21	1	1	NUM
bjp-23039	61	22	)	)	PUNCT
bjp-23039	61	23	.	.	PUNCT
bjp-23039	62	1	to	to	PART
bjp-23039	62	2	further	far	ADV
bjp-23039	62	3	assess	assess	VERB
bjp-23039	62	4	apoptosis	apoptosis	NOUN
bjp-23039	62	5	induced	induce	VERB
bjp-23039	62	6	by	by	ADP
bjp-23039	62	7	fisetin	fisetin	NOUN
bjp-23039	62	8	,	,	PUNCT
bjp-23039	62	9	annexinv	annexinv	ADJ
bjp-23039	62	10	/	/	SYM
bjp-23039	62	11	pi	pi	NOUN
bjp-23039	62	12	staining	staining	NOUN
bjp-23039	62	13	followed	follow	VERB
bjp-23039	62	14	by	by	ADP
bjp-23039	62	15	facs	fac	NOUN
bjp-23039	62	16	analysis	analysis	NOUN
bjp-23039	62	17	was	be	AUX
bjp-23039	62	18	figure	figure	NOUN
bjp-23039	62	19	1	1	NUM
bjp-23039	62	20	:	:	PUNCT
bjp-23039	62	21	effect	effect	NOUN
bjp-23039	62	22	of	of	ADP
bjp-23039	62	23	fisetin	fisetin	NOUN
bjp-23039	62	24	on	on	ADP
bjp-23039	62	25	the	the	DET
bjp-23039	62	26	cell	cell	NOUN
bjp-23039	62	27	viability	viability	NOUN
bjp-23039	62	28	of	of	ADP
bjp-23039	62	29	u-2	u-2	PROPN
bjp-23039	62	30	os	os	PROPN
bjp-23039	62	31	cells	cell	NOUN
bjp-23039	62	32	values	value	NOUN
bjp-23039	62	33	are	be	AUX
bjp-23039	62	34	represented	represent	VERB
bjp-23039	62	35	as	as	ADP
bjp-23039	62	36	mean	mean	NOUN
bjp-23039	62	37	±	±	NUM
bjp-23039	62	38	sd	sd	NOUN
bjp-23039	62	39	;	;	PUNCT
bjp-23039	62	40	n=6	n=6	NUM
bjp-23039	62	41	;	;	PUNCT
bjp-23039	62	42	*	*	PUNCT
bjp-23039	62	43	represents	represent	VERB
bjp-23039	62	44	p<0.05	p<0.05	NOUN
bjp-23039	62	45	compared	compare	VERB
bjp-23039	62	46	with	with	ADP
bjp-23039	62	47	control	control	NOUN
bjp-23039	62	48	as	as	SCONJ
bjp-23039	62	49	determined	determine	VERB
bjp-23039	62	50	by	by	ADP
bjp-23039	62	51	one	one	NUM
bjp-23039	62	52	way	way	NOUN
bjp-23039	62	53	-	-	PUNCT
bjp-23039	62	54	anova	anova	ADJ
bjp-23039	62	55	figure	figure	NOUN
bjp-23039	62	56	2	2	NUM
bjp-23039	62	57	:	:	PUNCT
bjp-23039	62	58	influence	influence	NOUN
bjp-23039	62	59	of	of	ADP
bjp-23039	62	60	fisetin	fisetin	NOUN
bjp-23039	62	61	on	on	ADP
bjp-23039	62	62	apoptotic	apoptotic	ADJ
bjp-23039	62	63	cell	cell	NOUN
bjp-23039	62	64	counts	count	NOUN
bjp-23039	62	65	fisetin	fisetin	VERB
bjp-23039	62	66	induced	induced	ADJ
bjp-23039	62	67	apoptosis	apoptosis	NOUN
bjp-23039	62	68	of	of	ADP
bjp-23039	62	69	the	the	DET
bjp-23039	62	70	u-2	u-2	PROPN
bjp-23039	62	71	os	os	PROPN
bjp-23039	62	72	cells	cell	NOUN
bjp-23039	62	73	in	in	ADP
bjp-23039	62	74	a	a	DET
bjp-23039	62	75	dose	dose	NOUN
bjp-23039	62	76	-	-	PUNCT
bjp-23039	62	77	dependent	dependent	ADJ
bjp-23039	62	78	manner	manner	NOUN
bjp-23039	62	79	as	as	SCONJ
bjp-23039	62	80	determined	determine	VERB
bjp-23039	62	81	by	by	ADP
bjp-23039	62	82	annexin	annexin	NOUN
bjp-23039	62	83	v	v	ADP
bjp-23039	62	84	staining	stain	VERB
bjp-23039	62	85	.	.	PUNCT
bjp-23039	63	1	values	value	NOUN
bjp-23039	63	2	are	be	AUX
bjp-23039	63	3	represented	represent	VERB
bjp-23039	63	4	as	as	ADP
bjp-23039	63	5	mean	mean	NOUN
bjp-23039	63	6	±	±	NUM
bjp-23039	63	7	sd	sd	NOUN
bjp-23039	63	8	;	;	PUNCT
bjp-23039	63	9	n=3	n=3	NUM
bjp-23039	63	10	;	;	PUNCT
bjp-23039	63	11	*	*	PUNCT
bjp-23039	63	12	represents	represent	VERB
bjp-23039	63	13	p<0.05	p<0.05	NOUN
bjp-23039	63	14	compared	compare	VERB
bjp-23039	63	15	with	with	ADP
bjp-23039	63	16	control	control	NOUN
bjp-23039	63	17	as	as	SCONJ
bjp-23039	63	18	determined	determine	VERB
bjp-23039	63	19	by	by	ADP
bjp-23039	63	20	one	one	NUM
bjp-23039	63	21	way	way	NOUN
bjp-23039	63	22	-	-	PUNCT
bjp-23039	63	23	anova	anova	PROPN
bjp-23039	63	24	c	c	PROPN
bjp-23039	63	25	el	el	PROPN
bjp-23039	63	26	l	l	PROPN
bjp-23039	63	27	v	v	X
bjp-23039	63	28	ia	ia	PROPN
bjp-23039	63	29	bi	bi	PROPN
bjp-23039	63	30	lit	light	VERB
bjp-23039	63	31	y	y	PROPN
bjp-23039	63	32	(	(	PUNCT
bjp-23039	63	33	%	%	NOUN
bjp-23039	63	34	)	)	PUNCT
bjp-23039	63	35	120	120	NUM
bjp-23039	63	36	100	100	NUM
bjp-23039	63	37	80	80	NUM
bjp-23039	63	38	60	60	NUM
bjp-23039	63	39	40	40	NUM
bjp-23039	63	40	20	20	NUM
bjp-23039	63	41	0	0	NUM
bjp-23039	63	42	control	control	NOUN
bjp-23039	63	43	20	20	NUM
bjp-23039	63	44	µm	µm	NOUN
bjp-23039	63	45	fisetin	fisetin	VERB
bjp-23039	63	46	12	12	NUM
bjp-23039	63	47	hours	hour	NOUN
bjp-23039	63	48	24	24	NUM
bjp-23039	63	49	hours	hour	NOUN
bjp-23039	63	50	48	48	NUM
bjp-23039	63	51	hours	hour	NOUN
bjp-23039	63	52	40	40	NUM
bjp-23039	63	53	µm	µm	NOUN
bjp-23039	63	54	fisetin	fisetin	VERB
bjp-23039	63	55	60	60	NUM
bjp-23039	63	56	µm	µm	NOUN
bjp-23039	63	57	fisetin	fisetin	VERB
bjp-23039	63	58	80	80	NUM
bjp-23039	63	59	µm	µm	NOUN
bjp-23039	63	60	fisetin	fisetin	VERB
bjp-23039	63	61	100	100	NUM
bjp-23039	63	62	µm	µm	NOUN
bjp-23039	63	63	fisetin	fisetin	NOUN
bjp-23039	63	64	*	*	PUNCT
bjp-23039	64	1	*	*	PUNCT
bjp-23039	65	1	*	*	PUNCT
bjp-23039	66	1	*	*	PUNCT
bjp-23039	67	1	*	*	PUNCT
bjp-23039	68	1	*	*	PUNCT
bjp-23039	69	1	*	*	PUNCT
bjp-23039	70	1	*	*	PUNCT
bjp-23039	71	1	*	*	PUNCT
bjp-23039	72	1	*	*	PUNCT
bjp-23039	73	1	*	*	PUNCT
bjp-23039	74	1	*	*	PUNCT
bjp-23039	74	2	*	*	PUNCT
bjp-23039	74	3	*	*	PUNCT
bjp-23039	74	4	*	*	PUNCT
bjp-23039	74	5	control	control	NOUN
bjp-23039	74	6	20	20	NUM
bjp-23039	74	7	µm	µm	NOUN
bjp-23039	74	8	fisetin	fisetin	VERB
bjp-23039	74	9	40	40	NUM
bjp-23039	74	10	µm	µm	NOUN
bjp-23039	74	11	fisetin	fisetin	VERB
bjp-23039	74	12	60	60	NUM
bjp-23039	74	13	µm	µm	NOUN
bjp-23039	74	14	fisetin	fisetin	VERB
bjp-23039	74	15	80	80	NUM
bjp-23039	74	16	µm	µm	NOUN
bjp-23039	74	17	fisetin	fisetin	VERB
bjp-23039	74	18	100	100	NUM
bjp-23039	74	19	µm	µm	NOUN
bjp-23039	74	20	fisetin	fisetin	VERB
bjp-23039	74	21	12	12	NUM
bjp-23039	74	22	hours	hour	NOUN
bjp-23039	74	23	24	24	NUM
bjp-23039	74	24	hours	hour	NOUN
bjp-23039	74	25	48	48	NUM
bjp-23039	74	26	hours	hour	NOUN
bjp-23039	74	27	a	a	DET
bjp-23039	74	28	po	po	NOUN
bjp-23039	74	29	pt	pt	INTJ
bjp-23039	74	30	ot	ot	INTJ
bjp-23039	74	31	ic	ic	PROPN
bjp-23039	75	1	c	c	PROPN
bjp-23039	75	2	el	el	PROPN
bjp-23039	75	3	l	l	PROPN
bjp-23039	75	4	c	c	NOUN
bjp-23039	76	1	ou	ou	INTJ
bjp-23039	76	2	nt	not	PART
bjp-23039	76	3	s	s	X
bjp-23039	76	4	(	(	PUNCT
bjp-23039	76	5	%	%	NOUN
bjp-23039	76	6	)	)	PUNCT
bjp-23039	76	7	100	100	NUM
bjp-23039	76	8	75	75	NUM
bjp-23039	76	9	50	50	NUM
bjp-23039	76	10	25	25	NUM
bjp-23039	76	11	0	0	NUM
bjp-23039	77	1	*	*	PUNCT
bjp-23039	78	1	*	*	PUNCT
bjp-23039	79	1	*	*	PUNCT
bjp-23039	80	1	*	*	PUNCT
bjp-23039	81	1	*	*	PUNCT
bjp-23039	82	1	*	*	PUNCT
bjp-23039	83	1	*	*	PUNCT
bjp-23039	84	1	*	*	PUNCT
bjp-23039	85	1	*	*	PUNCT
bjp-23039	86	1	*	*	PUNCT
bjp-23039	87	1	*	*	PUNCT
bjp-23039	88	1	*	*	PUNCT
bjp-23039	89	1	*	*	PUNCT
bjp-23039	89	2	*	*	PUNCT
bjp-23039	89	3	*	*	PUNCT
bjp-23039	89	4	822	822	NUM
bjp-23039	89	5	bangladesh	bangladesh	PROPN
bjp-23039	89	6	j	j	PROPN
bjp-23039	89	7	pharmacol	pharmacol	PROPN
bjp-23039	89	8	2015	2015	NUM
bjp-23039	89	9	;	;	PUNCT
bjp-23039	89	10	10	10	NUM
bjp-23039	89	11	:	:	SYM
bjp-23039	89	12	820	820	NUM
bjp-23039	89	13	-	-	SYM
bjp-23039	89	14	829	829	NUM
bjp-23039	89	15	performed	perform	VERB
bjp-23039	89	16	.	.	PUNCT
bjp-23039	90	1	fisetin	fisetin	PROPN
bjp-23039	90	2	caused	cause	VERB
bjp-23039	90	3	significant	significant	ADJ
bjp-23039	90	4	(	(	PUNCT
bjp-23039	90	5	p<0.05	p<0.05	NOUN
bjp-23039	90	6	)	)	PUNCT
bjp-23039	90	7	increases	increase	NOUN
bjp-23039	90	8	in	in	ADP
bjp-23039	90	9	apoptotic	apoptotic	ADJ
bjp-23039	90	10	cell	cell	NOUN
bjp-23039	90	11	counts	count	NOUN
bjp-23039	90	12	(	(	PUNCT
bjp-23039	90	13	figure	figure	NOUN
bjp-23039	90	14	2	2	NUM
bjp-23039	90	15	)	)	PUNCT
bjp-23039	90	16	.	.	PUNCT
bjp-23039	91	1	fisetin	fisetin	NOUN
bjp-23039	91	2	at	at	ADP
bjp-23039	91	3	100	100	NUM
bjp-23039	91	4	µm	µm	NUM
bjp-23039	91	5	exhibited	exhibit	VERB
bjp-23039	91	6	more	more	ADV
bjp-23039	91	7	profound	profound	ADJ
bjp-23039	91	8	effects	effect	NOUN
bjp-23039	91	9	than	than	ADP
bjp-23039	91	10	the	the	DET
bjp-23039	91	11	lower	low	ADJ
bjp-23039	91	12	concentrations	concentration	NOUN
bjp-23039	91	13	.	.	PUNCT
bjp-23039	92	1	moreover	moreover	ADV
bjp-23039	92	2	,	,	PUNCT
bjp-23039	92	3	the	the	DET
bjp-23039	92	4	time	time	NOUN
bjp-23039	92	5	of	of	ADP
bjp-23039	92	6	exposure	exposure	NOUN
bjp-23039	92	7	to	to	PART
bjp-23039	92	8	fisetin	fisetin	VERB
bjp-23039	92	9	also	also	ADV
bjp-23039	92	10	influenced	influence	VERB
bjp-23039	92	11	the	the	DET
bjp-23039	92	12	effects	effect	NOUN
bjp-23039	92	13	.	.	PUNCT
bjp-23039	93	1	incubation	incubation	NOUN
bjp-23039	93	2	with	with	ADP
bjp-23039	93	3	fisetin	fisetin	NOUN
bjp-23039	93	4	for	for	ADP
bjp-23039	93	5	48	48	NUM
bjp-23039	93	6	hours	hour	NOUN
bjp-23039	93	7	brought	bring	VERB
bjp-23039	93	8	about	about	ADP
bjp-23039	93	9	more	more	ADJ
bjp-23039	93	10	apoptosis	apoptosis	NOUN
bjp-23039	93	11	than	than	ADP
bjp-23039	93	12	24	24	NUM
bjp-23039	93	13	or	or	CCONJ
bjp-23039	93	14	12	12	NUM
bjp-23039	93	15	hours	hour	NOUN
bjp-23039	93	16	of	of	ADP
bjp-23039	93	17	exposure	exposure	NOUN
bjp-23039	93	18	.	.	PUNCT
bjp-23039	94	1	significant	significant	ADJ
bjp-23039	94	2	(	(	PUNCT
bjp-23039	94	3	p<0.05	p<0.05	NOUN
bjp-23039	94	4	)	)	PUNCT
bjp-23039	94	5	difference	difference	NOUN
bjp-23039	94	6	were	be	AUX
bjp-23039	94	7	observed	observe	VERB
bjp-23039	94	8	between	between	ADP
bjp-23039	94	9	the	the	DET
bjp-23039	94	10	apoptotic	apoptotic	ADJ
bjp-23039	94	11	cell	cell	NOUN
bjp-23039	94	12	counts	count	NOUN
bjp-23039	94	13	following	follow	VERB
bjp-23039	94	14	24	24	NUM
bjp-23039	94	15	and	and	CCONJ
bjp-23039	94	16	48	48	NUM
bjp-23039	94	17	hours	hour	NOUN
bjp-23039	94	18	of	of	ADP
bjp-23039	94	19	fisetin	fisetin	ADJ
bjp-23039	94	20	treatment	treatment	NOUN
bjp-23039	94	21	.	.	PUNCT
bjp-23039	95	1	effects	effect	NOUN
bjp-23039	95	2	of	of	ADP
bjp-23039	95	3	fisetin	fisetin	NOUN
bjp-23039	95	4	on	on	ADP
bjp-23039	95	5	apoptotic	apoptotic	ADJ
bjp-23039	95	6	protein	protein	NOUN
bjp-23039	95	7	expression	expression	NOUN
bjp-23039	95	8	caspases-3,-9	caspases-3,-9	PROPN
bjp-23039	95	9	and	and	CCONJ
bjp-23039	95	10	-8	-8	NOUN
bjp-23039	95	11	were	be	AUX
bjp-23039	95	12	down	down	ADV
bjp-23039	95	13	-	-	PUNCT
bjp-23039	95	14	regulated	regulate	VERB
bjp-23039	95	15	in	in	ADP
bjp-23039	95	16	u2	u2	NOUN
bjp-23039	95	17	-	-	PUNCT
bjp-23039	95	18	os	os	NOUN
bjp-23039	95	19	cells	cell	NOUN
bjp-23039	95	20	,	,	PUNCT
bjp-23039	95	21	suggesting	suggest	VERB
bjp-23039	95	22	suppression	suppression	NOUN
bjp-23039	95	23	of	of	ADP
bjp-23039	95	24	apoptosis	apoptosis	NOUN
bjp-23039	95	25	in	in	ADP
bjp-23039	95	26	cancer	cancer	NOUN
bjp-23039	95	27	cells	cell	NOUN
bjp-23039	95	28	.	.	PUNCT
bjp-23039	96	1	however	however	ADV
bjp-23039	96	2	,	,	PUNCT
bjp-23039	96	3	fisetin	fisetin	ADJ
bjp-23039	96	4	effectively	effectively	ADV
bjp-23039	96	5	caused	cause	VERB
bjp-23039	96	6	significant	significant	ADJ
bjp-23039	96	7	(	(	PUNCT
bjp-23039	96	8	p<0.05	p<0.05	NOUN
bjp-23039	96	9	)	)	PUNCT
bjp-23039	96	10	up	up	ADP
bjp-23039	96	11	-	-	PUNCT
bjp-23039	96	12	regulation	regulation	NOUN
bjp-23039	96	13	in	in	ADP
bjp-23039	96	14	the	the	DET
bjp-23039	96	15	expression	expression	NOUN
bjp-23039	96	16	of	of	ADP
bjp-23039	96	17	cleaved	cleaved	ADJ
bjp-23039	96	18	caspase	caspase	NOUN
bjp-23039	96	19	-3,-8	-3,-8	X
bjp-23039	96	20	and	and	CCONJ
bjp-23039	96	21	-9	-9	INTJ
bjp-23039	96	22	,	,	PUNCT
bjp-23039	96	23	thus	thus	ADV
bjp-23039	96	24	promoting	promote	VERB
bjp-23039	96	25	the	the	DET
bjp-23039	96	26	apoptotic	apoptotic	ADJ
bjp-23039	96	27	cascades	cascade	NOUN
bjp-23039	96	28	(	(	PUNCT
bjp-23039	96	29	figure	figure	NOUN
bjp-23039	96	30	3	3	NUM
bjp-23039	96	31	)	)	PUNCT
bjp-23039	96	32	.	.	PUNCT
bjp-23039	97	1	further	far	ADV
bjp-23039	97	2	,	,	PUNCT
bjp-23039	97	3	fisetin	fisetin	VERB
bjp-23039	97	4	at	at	ADP
bjp-23039	97	5	100	100	NUM
bjp-23039	97	6	µm	µm	ADP
bjp-23039	97	7	dose	dose	NOUN
bjp-23039	97	8	was	be	AUX
bjp-23039	97	9	more	more	ADV
bjp-23039	97	10	effective	effective	ADJ
bjp-23039	97	11	in	in	ADP
bjp-23039	97	12	enhancing	enhance	VERB
bjp-23039	97	13	the	the	DET
bjp-23039	97	14	expression	expression	NOUN
bjp-23039	97	15	of	of	ADP
bjp-23039	97	16	caspases	caspase	NOUN
bjp-23039	97	17	than	than	ADP
bjp-23039	97	18	20	20	NUM
bjp-23039	97	19	-	-	SYM
bjp-23039	97	20	60	60	NUM
bjp-23039	97	21	µm	µm	NOUN
bjp-23039	97	22	.	.	PUNCT
bjp-23039	97	23	significant	significant	ADJ
bjp-23039	97	24	(	(	PUNCT
bjp-23039	97	25	p<0.05	p<0.05	NOUN
bjp-23039	97	26	)	)	PUNCT
bjp-23039	97	27	increase	increase	NOUN
bjp-23039	97	28	in	in	ADP
bjp-23039	97	29	the	the	DET
bjp-23039	97	30	levels	level	NOUN
bjp-23039	97	31	of	of	ADP
bjp-23039	97	32	bcl-2	bcl-2	NOUN
bjp-23039	97	33	and	and	CCONJ
bjp-23039	97	34	bcl	bcl	PROPN
bjp-23039	97	35	-	-	PROPN
bjp-23039	97	36	xl	xl	PROPN
bjp-23039	97	37	expressions	expression	NOUN
bjp-23039	97	38	in	in	ADP
bjp-23039	97	39	the	the	DET
bjp-23039	97	40	u-2	u-2	PROPN
bjp-23039	97	41	os	os	PROPN
bjp-23039	97	42	cells	cell	NOUN
bjp-23039	97	43	was	be	AUX
bjp-23039	97	44	observed	observe	VERB
bjp-23039	97	45	,	,	PUNCT
bjp-23039	97	46	nevertheless	nevertheless	ADV
bjp-23039	97	47	following	follow	VERB
bjp-23039	97	48	fisetin	fisetin	NOUN
bjp-23039	97	49	exposure	exposure	NOUN
bjp-23039	97	50	caused	cause	VERB
bjp-23039	97	51	significant	significant	ADJ
bjp-23039	97	52	down	down	ADJ
bjp-23039	97	53	-	-	PUNCT
bjp-23039	97	54	regulation	regulation	NOUN
bjp-23039	97	55	in	in	ADP
bjp-23039	97	56	the	the	DET
bjp-23039	97	57	expression	expression	NOUN
bjp-23039	97	58	.	.	PUNCT
bjp-23039	98	1	in	in	ADP
bjp-23039	98	2	addition	addition	NOUN
bjp-23039	98	3	,	,	PUNCT
bjp-23039	98	4	the	the	DET
bjp-23039	98	5	level	level	NOUN
bjp-23039	98	6	of	of	ADP
bjp-23039	98	7	pro	pro	ADJ
bjp-23039	98	8	-	-	ADJ
bjp-23039	98	9	apoptotic	apoptotic	ADJ
bjp-23039	98	10	proteins	protein	NOUN
bjp-23039	98	11	such	such	ADJ
bjp-23039	98	12	as	as	ADP
bjp-23039	98	13	bax	bax	PROPN
bjp-23039	98	14	and	and	CCONJ
bjp-23039	98	15	bad	bad	ADJ
bjp-23039	98	16	that	that	PRON
bjp-23039	98	17	mainly	mainly	ADV
bjp-23039	98	18	modulate	modulate	VERB
bjp-23039	98	19	apoptosis	apoptosis	NOUN
bjp-23039	98	20	,	,	PUNCT
bjp-23039	98	21	were	be	AUX
bjp-23039	98	22	enhanced	enhance	VERB
bjp-23039	98	23	observably	observably	ADV
bjp-23039	98	24	in	in	ADP
bjp-23039	98	25	the	the	DET
bjp-23039	98	26	u2	u2	NOUN
bjp-23039	98	27	-	-	PUNCT
bjp-23039	98	28	os	os	NOUN
bjp-23039	98	29	cells	cell	NOUN
bjp-23039	98	30	exposed	expose	VERB
bjp-23039	98	31	to	to	AUX
bjp-23039	98	32	fisetin	fisetin	VERB
bjp-23039	98	33	.	.	PUNCT
bjp-23039	99	1	up	up	ADP
bjp-23039	99	2	-	-	PUNCT
bjp-23039	99	3	regulation	regulation	NOUN
bjp-23039	99	4	of	of	ADP
bjp-23039	99	5	bax	bax	PROPN
bjp-23039	99	6	and	and	CCONJ
bjp-23039	99	7	bad	bad	ADJ
bjp-23039	99	8	correlated	correlate	VERB
bjp-23039	99	9	with	with	ADP
bjp-23039	99	10	the	the	DET
bjp-23039	99	11	down	down	NOUN
bjp-23039	99	12	-	-	PUNCT
bjp-23039	99	13	regulation	regulation	NOUN
bjp-23039	99	14	of	of	ADP
bjp-23039	99	15	inhibitors	inhibitor	NOUN
bjp-23039	99	16	of	of	ADP
bjp-23039	99	17	apoptosisbcl-2	apoptosisbcl-2	NUM
bjp-23039	99	18	and	and	CCONJ
bjp-23039	99	19	bcl	bcl	PROPN
bjp-23039	99	20	-	-	PROPN
bjp-23039	99	21	xl	xl	PROPN
bjp-23039	99	22	.	.	PUNCT
bjp-23039	100	1	decrease	decrease	NOUN
bjp-23039	100	2	in	in	ADP
bjp-23039	100	3	mitochondrial	mitochondrial	ADJ
bjp-23039	100	4	transmembrane	transmembrane	NOUN
bjp-23039	100	5	potential	potential	NOUN
bjp-23039	100	6	indicates	indicate	VERB
bjp-23039	100	7	early	early	ADJ
bjp-23039	100	8	apoptosis	apoptosis	NOUN
bjp-23039	100	9	.	.	PUNCT
bjp-23039	101	1	fisetin	fisetin	PROPN
bjp-23039	101	2	exposure	exposure	NOUN
bjp-23039	101	3	resulted	result	VERB
bjp-23039	101	4	in	in	ADP
bjp-23039	101	5	a	a	DET
bjp-23039	101	6	noticeable	noticeable	ADJ
bjp-23039	101	7	decline	decline	NOUN
bjp-23039	101	8	of	of	ADP
bjp-23039	101	9	mitochondrial	mitochondrial	ADJ
bjp-23039	101	10	transmembrane	transmembrane	NOUN
bjp-23039	101	11	potential	potential	NOUN
bjp-23039	101	12	(	(	PUNCT
bjp-23039	101	13	δψm	δψm	PROPN
bjp-23039	101	14	)	)	PUNCT
bjp-23039	101	15	in	in	ADP
bjp-23039	101	16	a	a	DET
bjp-23039	101	17	dose	dose	NOUN
bjp-23039	101	18	-	-	PUNCT
bjp-23039	101	19	dependent	dependent	ADJ
bjp-23039	101	20	manner	manner	NOUN
bjp-23039	101	21	(	(	PUNCT
bjp-23039	101	22	figure	figure	NOUN
bjp-23039	101	23	4	4	NUM
bjp-23039	101	24	)	)	PUNCT
bjp-23039	101	25	.	.	PUNCT
bjp-23039	102	1	bcl-2	bcl-2	NOUN
bjp-23039	102	2	and	and	CCONJ
bjp-23039	102	3	bcl	bcl	PROPN
bjp-23039	102	4	-	-	PROPN
bjp-23039	102	5	xl	xl	PROPN
bjp-23039	102	6	proteins	protein	NOUN
bjp-23039	102	7	modulate	modulate	VERB
bjp-23039	102	8	apoptosis	apoptosis	NOUN
bjp-23039	102	9	at	at	ADP
bjp-23039	102	10	the	the	DET
bjp-23039	102	11	mitochondrial	mitochondrial	ADJ
bjp-23039	102	12	outer	outer	ADJ
bjp-23039	102	13	membrane	membrane	NOUN
bjp-23039	102	14	and	and	CCONJ
bjp-23039	102	15	control	control	VERB
bjp-23039	102	16	the	the	DET
bjp-23039	102	17	initiation	initiation	NOUN
bjp-23039	102	18	of	of	ADP
bjp-23039	102	19	mitochondrial	mitochondrial	ADJ
bjp-23039	102	20	outer	outer	ADJ
bjp-23039	102	21	membrane	membrane	NOUN
bjp-23039	102	22	permeabilization	permeabilization	NOUN
bjp-23039	102	23	(	(	PUNCT
bjp-23039	102	24	anilkumar	anilkumar	PROPN
bjp-23039	102	25	and	and	CCONJ
bjp-23039	102	26	prehn	prehn	NOUN
bjp-23039	102	27	,	,	PUNCT
bjp-23039	102	28	2014	2014	NUM
bjp-23039	102	29	)	)	PUNCT
bjp-23039	102	30	.	.	PUNCT
bjp-23039	103	1	in	in	ADP
bjp-23039	103	2	our	our	PRON
bjp-23039	103	3	study	study	NOUN
bjp-23039	103	4	,	,	PUNCT
bjp-23039	103	5	bclfigure	bclfigure	NOUN
bjp-23039	103	6	3	3	NUM
bjp-23039	103	7	:	:	PUNCT
bjp-23039	103	8	influence	influence	NOUN
bjp-23039	103	9	of	of	ADP
bjp-23039	103	10	fisetin	fisetin	NOUN
bjp-23039	103	11	on	on	ADP
bjp-23039	103	12	the	the	DET
bjp-23039	103	13	expression	expression	NOUN
bjp-23039	103	14	of	of	ADP
bjp-23039	103	15	apoptosis	apoptosis	NOUN
bjp-23039	103	16	pathway	pathway	NOUN
bjp-23039	103	17	proteins	protein	NOUN
bjp-23039	103	18	(	(	PUNCT
bjp-23039	103	19	a	a	PRON
bjp-23039	103	20	)	)	PUNCT
bjp-23039	103	21	fisetin	fisetin	VERB
bjp-23039	103	22	markedly	markedly	ADV
bjp-23039	103	23	up	up	ADV
bjp-23039	103	24	-	-	PUNCT
bjp-23039	103	25	regulated	regulate	VERB
bjp-23039	103	26	the	the	DET
bjp-23039	103	27	pro	pro	ADJ
bjp-23039	103	28	-	-	ADJ
bjp-23039	103	29	apoptotic	apoptotic	ADJ
bjp-23039	103	30	proteins	protein	NOUN
bjp-23039	103	31	and	and	CCONJ
bjp-23039	103	32	reduced	reduce	VERB
bjp-23039	103	33	the	the	DET
bjp-23039	103	34	expressions	expression	NOUN
bjp-23039	103	35	of	of	ADP
bjp-23039	103	36	bcl-2	bcl-2	NOUN
bjp-23039	103	37	and	and	CCONJ
bjp-23039	103	38	bcl	bcl	PROPN
bjp-23039	103	39	-	-	PROPN
bjp-23039	103	40	xl	xl	PROPN
bjp-23039	103	41	.	.	PUNCT
bjp-23039	104	1	(	(	PUNCT
bjp-23039	104	2	b	b	X
bjp-23039	104	3	)	)	PUNCT
bjp-23039	104	4	relative	relative	ADJ
bjp-23039	104	5	expression	expression	NOUN
bjp-23039	104	6	of	of	ADP
bjp-23039	104	7	the	the	DET
bjp-23039	104	8	proteins	protein	NOUN
bjp-23039	104	9	.	.	PUNCT
bjp-23039	105	1	values	value	NOUN
bjp-23039	105	2	are	be	AUX
bjp-23039	105	3	represented	represent	VERB
bjp-23039	105	4	as	as	ADP
bjp-23039	105	5	mean	mean	NOUN
bjp-23039	105	6	±	±	NUM
bjp-23039	105	7	sd	sd	NOUN
bjp-23039	105	8	;	;	PUNCT
bjp-23039	105	9	n=3	n=3	NUM
bjp-23039	105	10	;	;	PUNCT
bjp-23039	105	11	*	*	PUNCT
bjp-23039	105	12	represents	represent	VERB
bjp-23039	105	13	p<0.05	p<0.05	NOUN
bjp-23039	105	14	compared	compare	VERB
bjp-23039	105	15	with	with	ADP
bjp-23039	105	16	control	control	NOUN
bjp-23039	105	17	as	as	SCONJ
bjp-23039	105	18	determined	determine	VERB
bjp-23039	105	19	by	by	ADP
bjp-23039	105	20	one	one	NUM
bjp-23039	105	21	way	way	NOUN
bjp-23039	105	22	-	-	PUNCT
bjp-23039	105	23	anova	anova	X
bjp-23039	105	24	r	r	X
bjp-23039	105	25	el	el	PROPN
bjp-23039	105	26	at	at	ADP
bjp-23039	105	27	iv	iv	NUM
bjp-23039	105	28	e	e	X
bjp-23039	105	29	ex	ex	X
bjp-23039	105	30	pr	pr	VERB
bjp-23039	105	31	es	es	X
bjp-23039	105	32	si	si	X
bjp-23039	105	33	on	on	ADP
bjp-23039	105	34	(	(	PUNCT
bjp-23039	105	35	%	%	INTJ
bjp-23039	105	36	o	o	X
bjp-23039	105	37	f	f	X
bjp-23039	105	38	c	c	NOUN
bjp-23039	105	39	on	on	ADP
bjp-23039	105	40	tro	tro	X
bjp-23039	105	41	l	l	NOUN
bjp-23039	105	42	)	)	PUNCT
bjp-23039	105	43	250	250	NUM
bjp-23039	105	44	200	200	NUM
bjp-23039	105	45	150	150	NUM
bjp-23039	105	46	100	100	NUM
bjp-23039	105	47	50	50	NUM
bjp-23039	105	48	0	0	NUM
bjp-23039	105	49	control	control	NOUN
bjp-23039	105	50	20	20	NUM
bjp-23039	105	51	µm	µm	NOUN
bjp-23039	105	52	fisetin	fisetin	VERB
bjp-23039	105	53	40	40	NUM
bjp-23039	105	54	µm	µm	NOUN
bjp-23039	105	55	fisetin	fisetin	VERB
bjp-23039	105	56	60	60	NUM
bjp-23039	105	57	µm	µm	NOUN
bjp-23039	105	58	fisetin	fisetin	VERB
bjp-23039	105	59	80	80	NUM
bjp-23039	105	60	µm	µm	NOUN
bjp-23039	105	61	fisetin	fisetin	VERB
bjp-23039	105	62	100	100	NUM
bjp-23039	105	63	µm	µm	NOUN
bjp-23039	105	64	fisetin	fisetin	X
bjp-23039	105	65	*	*	PUNCT
bjp-23039	105	66	bcl-2	bcl-2	VERB
bjp-23039	105	67	bcl	bcl	PROPN
bjp-23039	105	68	-	-	PROPN
bjp-23039	105	69	xl	xl	PROPN
bjp-23039	105	70	bad	bad	ADJ
bjp-23039	105	71	bax	bax	PROPN
bjp-23039	105	72	caspase-3	caspase-3	NUM
bjp-23039	105	73	caspase-8	caspase-8	PROPN
bjp-23039	105	74	caspase-9	caspase-9	NUM
bjp-23039	105	75	*	*	PUNCT
bjp-23039	106	1	*	*	PUNCT
bjp-23039	107	1	*	*	PUNCT
bjp-23039	108	1	*	*	PUNCT
bjp-23039	109	1	*	*	PUNCT
bjp-23039	110	1	*	*	PUNCT
bjp-23039	111	1	*	*	PUNCT
bjp-23039	112	1	*	*	PUNCT
bjp-23039	113	1	*	*	PUNCT
bjp-23039	114	1	*	*	PUNCT
bjp-23039	115	1	*	*	PUNCT
bjp-23039	116	1	*	*	PUNCT
bjp-23039	117	1	*	*	PUNCT
bjp-23039	118	1	*	*	PUNCT
bjp-23039	119	1	*	*	PUNCT
bjp-23039	120	1	*	*	PUNCT
bjp-23039	121	1	*	*	PUNCT
bjp-23039	122	1	*	*	PUNCT
bjp-23039	122	2	*	*	PUNCT
bjp-23039	123	1	*	*	PUNCT
bjp-23039	124	1	*	*	PUNCT
bjp-23039	125	1	*	*	PUNCT
bjp-23039	125	2	*	*	PUNCT
bjp-23039	126	1	*	*	PUNCT
bjp-23039	127	1	*	*	PUNCT
bjp-23039	128	1	*	*	PUNCT
bjp-23039	128	2	*	*	PUNCT
bjp-23039	129	1	*	*	PUNCT
bjp-23039	130	1	*	*	PUNCT
bjp-23039	131	1	*	*	PUNCT
bjp-23039	131	2	*	*	PUNCT
bjp-23039	131	3	*	*	PUNCT
bjp-23039	131	4	*	*	PUNCT
bjp-23039	131	5	*	*	PUNCT
bjp-23039	131	6	bcl-2	bcl-2	VERB
bjp-23039	131	7	bcl	bcl	PROPN
bjp-23039	131	8	-	-	PROPN
bjp-23039	131	9	xl	xl	PROPN
bjp-23039	131	10	bad	bad	ADJ
bjp-23039	131	11	bax	bax	PROPN
bjp-23039	131	12	caspase-3	caspase-3	NUM
bjp-23039	131	13	caspase-8	caspase-8	PROPN
bjp-23039	131	14	caspase-9	caspase-9	PROPN
bjp-23039	131	15	β	β	NOUN
bjp-23039	131	16	-	-	NOUN
bjp-23039	131	17	actin	actin	NOUN
bjp-23039	131	18	µm	µm	X
bjp-23039	131	19	fisetin	fisetin	VERB
bjp-23039	131	20	0	0	NUM
bjp-23039	131	21	20	20	NUM
bjp-23039	131	22	40	40	NUM
bjp-23039	131	23	60	60	NUM
bjp-23039	131	24	80	80	NUM
bjp-23039	131	25	100	100	NUM
bjp-23039	131	26	a	a	DET
bjp-23039	131	27	b	b	PROPN
bjp-23039	131	28	bangladesh	bangladesh	NOUN
bjp-23039	131	29	j	j	PROPN
bjp-23039	131	30	pharmacol	pharmacol	PROPN
bjp-23039	131	31	2015	2015	NUM
bjp-23039	131	32	;	;	PUNCT
bjp-23039	131	33	10	10	NUM
bjp-23039	131	34	:	:	SYM
bjp-23039	131	35	820	820	NUM
bjp-23039	131	36	-	-	SYM
bjp-23039	131	37	829	829	NUM
bjp-23039	131	38	823	823	NUM
bjp-23039	131	39	figure	figure	NOUN
bjp-23039	131	40	4	4	NUM
bjp-23039	131	41	:	:	PUNCT
bjp-23039	131	42	effect	effect	NOUN
bjp-23039	131	43	of	of	ADP
bjp-23039	131	44	fisetin	fisetin	NOUN
bjp-23039	131	45	on	on	ADP
bjp-23039	131	46	the	the	DET
bjp-23039	131	47	mitochondrial	mitochondrial	ADJ
bjp-23039	131	48	membrane	membrane	NOUN
bjp-23039	131	49	potential	potential	NOUN
bjp-23039	131	50	of	of	ADP
bjp-23039	131	51	u-2	u-2	PROPN
bjp-23039	131	52	os	os	PROPN
bjp-23039	131	53	cells	cell	NOUN
bjp-23039	131	54	values	value	NOUN
bjp-23039	131	55	are	be	AUX
bjp-23039	131	56	represented	represent	VERB
bjp-23039	131	57	as	as	ADP
bjp-23039	131	58	mean	mean	NOUN
bjp-23039	131	59	±	±	NUM
bjp-23039	131	60	sd	sd	NOUN
bjp-23039	131	61	;	;	PUNCT
bjp-23039	131	62	n=3	n=3	NUM
bjp-23039	131	63	;	;	PUNCT
bjp-23039	131	64	*	*	PUNCT
bjp-23039	131	65	represents	represent	VERB
bjp-23039	131	66	p<0.05	p<0.05	NOUN
bjp-23039	131	67	compared	compare	VERB
bjp-23039	131	68	with	with	ADP
bjp-23039	131	69	control	control	NOUN
bjp-23039	131	70	as	as	SCONJ
bjp-23039	131	71	determined	determine	VERB
bjp-23039	131	72	by	by	ADP
bjp-23039	131	73	one	one	NUM
bjp-23039	131	74	way	way	NOUN
bjp-23039	131	75	-	-	PUNCT
bjp-23039	131	76	anova	anova	ADJ
bjp-23039	131	77	figure	figure	NOUN
bjp-23039	131	78	5	5	NUM
bjp-23039	131	79	:	:	PUNCT
bjp-23039	131	80	fisetin	fisetin	NOUN
bjp-23039	131	81	regulates	regulate	VERB
bjp-23039	131	82	the	the	DET
bjp-23039	131	83	expression	expression	NOUN
bjp-23039	131	84	of	of	ADP
bjp-23039	131	85	pi3k	pi3k	PROPN
bjp-23039	131	86	/	/	SYM
bjp-23039	131	87	akt	akt	PROPN
bjp-23039	131	88	pathway	pathway	NOUN
bjp-23039	131	89	proteins	protein	NOUN
bjp-23039	131	90	(	(	PUNCT
bjp-23039	131	91	a	a	DET
bjp-23039	131	92	)	)	PUNCT
bjp-23039	131	93	fisetin	fisetin	NOUN
bjp-23039	131	94	effectively	effectively	ADV
bjp-23039	131	95	modulates	modulate	VERB
bjp-23039	131	96	the	the	DET
bjp-23039	131	97	expressions	expression	NOUN
bjp-23039	131	98	of	of	ADP
bjp-23039	131	99	the	the	DET
bjp-23039	131	100	pi3k	pi3k	PROPN
bjp-23039	131	101	/	/	SYM
bjp-23039	131	102	akt	akt	PROPN
bjp-23039	131	103	signalling	signal	VERB
bjp-23039	131	104	proteins	protein	NOUN
bjp-23039	131	105	.	.	PUNCT
bjp-23039	132	1	fisetin	fisetin	PROPN
bjp-23039	132	2	dose	dose	NOUN
bjp-23039	132	3	-	-	PUNCT
bjp-23039	132	4	dependently	dependently	ADV
bjp-23039	132	5	inhibits	inhibit	VERB
bjp-23039	132	6	the	the	DET
bjp-23039	132	7	pathway	pathway	NOUN
bjp-23039	132	8	.	.	PUNCT
bjp-23039	133	1	(	(	PUNCT
bjp-23039	133	2	b	b	X
bjp-23039	133	3	)	)	PUNCT
bjp-23039	133	4	relative	relative	ADJ
bjp-23039	133	5	expressions	expression	NOUN
bjp-23039	133	6	of	of	ADP
bjp-23039	133	7	the	the	DET
bjp-23039	133	8	pi3k	pi3k	PROPN
bjp-23039	133	9	/	/	SYM
bjp-23039	133	10	akt	akt	PROPN
bjp-23039	133	11	pathway	pathway	NOUN
bjp-23039	133	12	proteins	protein	NOUN
bjp-23039	133	13	.	.	PUNCT
bjp-23039	134	1	values	value	NOUN
bjp-23039	134	2	are	be	AUX
bjp-23039	134	3	represented	represent	VERB
bjp-23039	134	4	as	as	ADP
bjp-23039	134	5	mean	mean	NOUN
bjp-23039	134	6	±	±	NUM
bjp-23039	134	7	sd	sd	NOUN
bjp-23039	134	8	;	;	PUNCT
bjp-23039	134	9	n=3	n=3	NUM
bjp-23039	134	10	;	;	PUNCT
bjp-23039	134	11	*	*	PUNCT
bjp-23039	134	12	represents	represent	VERB
bjp-23039	134	13	p<0.05	p<0.05	NOUN
bjp-23039	134	14	compared	compare	VERB
bjp-23039	134	15	with	with	ADP
bjp-23039	134	16	control	control	NOUN
bjp-23039	134	17	as	as	SCONJ
bjp-23039	134	18	determined	determine	VERB
bjp-23039	134	19	by	by	ADP
bjp-23039	134	20	one	one	NUM
bjp-23039	134	21	-	-	PUNCT
bjp-23039	134	22	way	way	NOUN
bjp-23039	134	23	anova	anova	PROPN
bjp-23039	134	24	a	a	DET
bjp-23039	134	25	100	100	NUM
bjp-23039	134	26	80	80	NUM
bjp-23039	134	27	60	60	NUM
bjp-23039	134	28	40	40	NUM
bjp-23039	134	29	20	20	NUM
bjp-23039	134	30	0	0	NUM
bjp-23039	134	31	m	m	PROPN
bjp-23039	134	32	ito	ito	PROPN
bjp-23039	134	33	ch	ch	PROPN
bjp-23039	134	34	on	on	ADP
bjp-23039	134	35	dr	dr	PROPN
bjp-23039	134	36	ia	ia	PROPN
bjp-23039	134	37	l	l	PROPN
bjp-23039	134	38	m	m	VERB
bjp-23039	134	39	em	em	PRON
bjp-23039	134	40	br	br	VERB
bjp-23039	134	41	an	an	DET
bjp-23039	134	42	e	e	X
bjp-23039	134	43	po	po	X
bjp-23039	134	44	te	te	PROPN
bjp-23039	134	45	nt	not	PART
bjp-23039	134	46	ia	ia	PROPN
bjp-23039	134	47	l	l	PROPN
bjp-23039	134	48	(	(	PUNCT
bjp-23039	134	49	%	%	INTJ
bjp-23039	134	50	o	o	X
bjp-23039	134	51	f	f	X
bjp-23039	134	52	co	co	VERB
bjp-23039	134	53	nt	not	PART
bjp-23039	134	54	ro	ro	PROPN
bjp-23039	134	55	l	l	NOUN
bjp-23039	134	56	)	)	PUNCT
bjp-23039	134	57	0	0	NUM
bjp-23039	134	58	20	20	NUM
bjp-23039	134	59	40	40	NUM
bjp-23039	134	60	60	60	NUM
bjp-23039	134	61	80	80	NUM
bjp-23039	134	62	100	100	NUM
bjp-23039	134	63	fisetin	fisetin	NOUN
bjp-23039	134	64	(	(	PUNCT
bjp-23039	134	65	µm	µm	NOUN
bjp-23039	134	66	)	)	PUNCT
bjp-23039	134	67	*	*	PUNCT
bjp-23039	135	1	*	*	PUNCT
bjp-23039	135	2	*	*	PUNCT
bjp-23039	135	3	*	*	PUNCT
bjp-23039	135	4	akt	akt	PROPN
bjp-23039	135	5	p	p	PROPN
bjp-23039	135	6	-	-	PUNCT
bjp-23039	135	7	akt	akt	PROPN
bjp-23039	135	8	pten	pten	VERB
bjp-23039	135	9	cyclin	cyclin	NOUN
bjp-23039	135	10	d1	d1	PROPN
bjp-23039	135	11	gsk3β	gsk3β	PROPN
bjp-23039	136	1	p	p	X
bjp-23039	136	2	-	-	PUNCT
bjp-23039	136	3	gsk3β	gsk3β	NOUN
bjp-23039	136	4	nf	nf	PROPN
bjp-23039	136	5	-	-	PUNCT
bjp-23039	136	6	kb	kb	PROPN
bjp-23039	136	7	ikb	ikb	PROPN
bjp-23039	136	8	mtorc1	mtorc1	NOUN
bjp-23039	136	9	β	β	NOUN
bjp-23039	136	10	-	-	PUNCT
bjp-23039	136	11	actin	actin	ADJ
bjp-23039	136	12	0	0	NUM
bjp-23039	136	13	20	20	NUM
bjp-23039	136	14	40	40	NUM
bjp-23039	136	15	60	60	NUM
bjp-23039	136	16	80	80	NUM
bjp-23039	136	17	100	100	NUM
bjp-23039	136	18	µm	µm	ADP
bjp-23039	136	19	fisetin	fisetin	NOUN
bjp-23039	136	20	b	b	PROPN
bjp-23039	136	21	r	r	NOUN
bjp-23039	136	22	el	el	PROPN
bjp-23039	136	23	at	at	ADP
bjp-23039	136	24	iv	iv	NUM
bjp-23039	137	1	e	e	X
bjp-23039	137	2	ex	ex	X
bjp-23039	137	3	pr	pr	VERB
bjp-23039	137	4	es	es	X
bjp-23039	137	5	si	si	X
bjp-23039	137	6	on	on	ADP
bjp-23039	137	7	(	(	PUNCT
bjp-23039	137	8	%	%	INTJ
bjp-23039	137	9	o	o	X
bjp-23039	138	1	f	f	X
bjp-23039	138	2	c	c	NOUN
bjp-23039	138	3	on	on	ADP
bjp-23039	138	4	tro	tro	X
bjp-23039	138	5	l	l	NOUN
bjp-23039	138	6	)	)	PUNCT
bjp-23039	138	7	250	250	NUM
bjp-23039	138	8	200	200	NUM
bjp-23039	138	9	150	150	NUM
bjp-23039	138	10	100	100	NUM
bjp-23039	138	11	50	50	NUM
bjp-23039	138	12	0	0	NUM
bjp-23039	138	13	control	control	NOUN
bjp-23039	138	14	20	20	NUM
bjp-23039	138	15	µm	µm	NOUN
bjp-23039	138	16	fisetin	fisetin	VERB
bjp-23039	138	17	40	40	NUM
bjp-23039	138	18	µm	µm	NOUN
bjp-23039	138	19	fisetin	fisetin	VERB
bjp-23039	138	20	60	60	NUM
bjp-23039	138	21	µm	µm	NOUN
bjp-23039	138	22	fisetin	fisetin	VERB
bjp-23039	138	23	80	80	NUM
bjp-23039	138	24	µm	µm	NOUN
bjp-23039	138	25	fisetin	fisetin	VERB
bjp-23039	138	26	100	100	NUM
bjp-23039	138	27	µm	µm	NOUN
bjp-23039	138	28	fisetin	fisetin	VERB
bjp-23039	138	29	akt	akt	PROPN
bjp-23039	138	30	p	p	PROPN
bjp-23039	138	31	-	-	PUNCT
bjp-23039	138	32	akt	akt	PROPN
bjp-23039	138	33	pten	pten	VERB
bjp-23039	138	34	cyclin	cyclin	NOUN
bjp-23039	138	35	d1	d1	PROPN
bjp-23039	138	36	gsk3β	gsk3β	PROPN
bjp-23039	139	1	p	p	X
bjp-23039	139	2	-	-	PUNCT
bjp-23039	139	3	gsk3β	gsk3β	NOUN
bjp-23039	139	4	nf	nf	PROPN
bjp-23039	139	5	-	-	PUNCT
bjp-23039	139	6	kb	kb	NOUN
bjp-23039	139	7	*	*	PUNCT
bjp-23039	140	1	*	*	PUNCT
bjp-23039	141	1	*	*	PUNCT
bjp-23039	142	1	*	*	PUNCT
bjp-23039	143	1	*	*	PUNCT
bjp-23039	144	1	*	*	PUNCT
bjp-23039	145	1	*	*	PUNCT
bjp-23039	145	2	*	*	PUNCT
bjp-23039	145	3	*	*	PUNCT
bjp-23039	145	4	ikb	ikb	VERB
bjp-23039	145	5	mtorc1	mtorc1	NOUN
bjp-23039	146	1	*	*	PUNCT
bjp-23039	147	1	*	*	PUNCT
bjp-23039	148	1	*	*	PUNCT
bjp-23039	149	1	*	*	PUNCT
bjp-23039	150	1	*	*	PUNCT
bjp-23039	151	1	*	*	PUNCT
bjp-23039	152	1	*	*	PUNCT
bjp-23039	153	1	*	*	PUNCT
bjp-23039	154	1	*	*	PUNCT
bjp-23039	154	2	*	*	PUNCT
bjp-23039	155	1	*	*	PUNCT
bjp-23039	156	1	*	*	PUNCT
bjp-23039	157	1	*	*	PUNCT
bjp-23039	157	2	*	*	PUNCT
bjp-23039	158	1	*	*	PUNCT
bjp-23039	159	1	*	*	PUNCT
bjp-23039	160	1	*	*	PUNCT
bjp-23039	161	1	*	*	PUNCT
bjp-23039	162	1	*	*	PUNCT
bjp-23039	163	1	*	*	PUNCT
bjp-23039	164	1	*	*	PUNCT
bjp-23039	165	1	*	*	PUNCT
bjp-23039	166	1	*	*	PUNCT
bjp-23039	167	1	*	*	PUNCT
bjp-23039	168	1	*	*	PUNCT
bjp-23039	169	1	*	*	PUNCT
bjp-23039	170	1	*	*	PUNCT
bjp-23039	171	1	*	*	PUNCT
bjp-23039	172	1	*	*	PUNCT
bjp-23039	172	2	*	*	PUNCT
bjp-23039	172	3	*	*	PUNCT
bjp-23039	172	4	824	824	NUM
bjp-23039	172	5	bangladesh	bangladesh	NOUN
bjp-23039	172	6	j	j	PROPN
bjp-23039	172	7	pharmacol	pharmacol	PROPN
bjp-23039	172	8	2015	2015	NUM
bjp-23039	172	9	;	;	PUNCT
bjp-23039	172	10	10	10	NUM
bjp-23039	172	11	:	:	SYM
bjp-23039	172	12	820	820	NUM
bjp-23039	172	13	-	-	SYM
bjp-23039	172	14	829	829	NUM
bjp-23039	172	15	xl	xl	PROPN
bjp-23039	172	16	and	and	CCONJ
bjp-23039	172	17	bcl-2	bcl-2	NOUN
bjp-23039	172	18	were	be	AUX
bjp-23039	172	19	down	down	ADV
bjp-23039	172	20	-	-	PUNCT
bjp-23039	172	21	regulated	regulate	VERB
bjp-23039	172	22	in	in	ADP
bjp-23039	172	23	a	a	DET
bjp-23039	172	24	concentrationdependent	concentrationdependent	NOUN
bjp-23039	172	25	manner	manner	NOUN
bjp-23039	172	26	after	after	ADP
bjp-23039	172	27	fisetin	fisetin	ADJ
bjp-23039	172	28	treatment	treatment	NOUN
bjp-23039	172	29	.	.	PUNCT
bjp-23039	173	1	this	this	PRON
bjp-23039	173	2	could	could	AUX
bjp-23039	173	3	have	have	AUX
bjp-23039	173	4	caused	cause	VERB
bjp-23039	173	5	alteration	alteration	NOUN
bjp-23039	173	6	in	in	ADP
bjp-23039	173	7	the	the	DET
bjp-23039	173	8	mitochondrial	mitochondrial	ADJ
bjp-23039	173	9	membrane	membrane	NOUN
bjp-23039	173	10	potential	potential	NOUN
bjp-23039	173	11	and	and	CCONJ
bjp-23039	173	12	thus	thus	ADV
bjp-23039	173	13	promoting	promote	VERB
bjp-23039	173	14	apoptosis	apoptosis	NOUN
bjp-23039	173	15	.	.	PUNCT
bjp-23039	174	1	effect	effect	NOUN
bjp-23039	174	2	of	of	ADP
bjp-23039	174	3	fisetin	fisetin	NOUN
bjp-23039	174	4	on	on	ADP
bjp-23039	174	5	pi3	pi3	NOUN
bjp-23039	174	6	/	/	SYM
bjp-23039	174	7	akt	akt	PROPN
bjp-23039	174	8	pathway	pathway	NOUN
bjp-23039	174	9	proteins	protein	NOUN
bjp-23039	174	10	activation	activation	NOUN
bjp-23039	174	11	of	of	ADP
bjp-23039	174	12	the	the	DET
bjp-23039	174	13	pi3k	pi3k	PROPN
bjp-23039	174	14	/	/	SYM
bjp-23039	174	15	akt	akt	PROPN
bjp-23039	174	16	pathway	pathway	NOUN
bjp-23039	174	17	plays	play	VERB
bjp-23039	174	18	a	a	DET
bjp-23039	174	19	critically	critically	ADV
bjp-23039	174	20	oncogenic	oncogenic	ADJ
bjp-23039	174	21	role	role	NOUN
bjp-23039	174	22	in	in	ADP
bjp-23039	174	23	the	the	DET
bjp-23039	174	24	initiation	initiation	NOUN
bjp-23039	174	25	and	and	CCONJ
bjp-23039	174	26	progression	progression	NOUN
bjp-23039	174	27	of	of	ADP
bjp-23039	174	28	os	os	PROPN
bjp-23039	174	29	(	(	PUNCT
bjp-23039	174	30	zhang	zhang	X
bjp-23039	174	31	et	et	PROPN
bjp-23039	174	32	al	al	PROPN
bjp-23039	174	33	.	.	PROPN
bjp-23039	174	34	,	,	PUNCT
bjp-23039	174	35	2015	2015	NUM
bjp-23039	174	36	)	)	PUNCT
bjp-23039	174	37	.	.	PUNCT
bjp-23039	175	1	effect	effect	NOUN
bjp-23039	175	2	fisetin	fisetin	NOUN
bjp-23039	175	3	over	over	ADP
bjp-23039	175	4	the	the	DET
bjp-23039	175	5	expressions	expression	NOUN
bjp-23039	175	6	of	of	ADP
bjp-23039	175	7	pi3	pi3	NOUN
bjp-23039	175	8	/	/	SYM
bjp-23039	175	9	akt	akt	PROPN
bjp-23039	175	10	pathway	pathway	NOUN
bjp-23039	175	11	proteins	protein	NOUN
bjp-23039	175	12	in	in	ADP
bjp-23039	175	13	u2	u2	NOUN
bjp-23039	175	14	-	-	PUNCT
bjp-23039	175	15	os	os	NOUN
bjp-23039	175	16	cells	cell	NOUN
bjp-23039	175	17	were	be	AUX
bjp-23039	175	18	assessed	assess	VERB
bjp-23039	175	19	.	.	PUNCT
bjp-23039	176	1	akt	akt	PROPN
bjp-23039	176	2	is	be	AUX
bjp-23039	176	3	a	a	DET
bjp-23039	176	4	critical	critical	ADJ
bjp-23039	176	5	signalling	signal	VERB
bjp-23039	176	6	junction	junction	NOUN
bjp-23039	176	7	downstream	downstream	NOUN
bjp-23039	176	8	of	of	ADP
bjp-23039	176	9	the	the	DET
bjp-23039	176	10	pi3k	pi3k	PROPN
bjp-23039	176	11	pathway	pathway	NOUN
bjp-23039	176	12	which	which	PRON
bjp-23039	176	13	is	be	AUX
bjp-23039	176	14	activated	activate	VERB
bjp-23039	176	15	through	through	ADP
bjp-23039	176	16	phosphorylation	phosphorylation	NOUN
bjp-23039	176	17	.	.	PUNCT
bjp-23039	177	1	p	p	X
bjp-23039	177	2	-	-	PUNCT
bjp-23039	177	3	akt	akt	PROPN
bjp-23039	177	4	levels	level	NOUN
bjp-23039	177	5	are	be	AUX
bjp-23039	177	6	raised	raise	VERB
bjp-23039	177	7	in	in	ADP
bjp-23039	177	8	os	os	NOUN
bjp-23039	177	9	cells	cell	NOUN
bjp-23039	177	10	,	,	PUNCT
bjp-23039	177	11	whereas	whereas	SCONJ
bjp-23039	177	12	pten	pten	NOUN
bjp-23039	177	13	,	,	PUNCT
bjp-23039	177	14	an	an	DET
bjp-23039	177	15	important	important	ADJ
bjp-23039	177	16	regulator	regulator	NOUN
bjp-23039	177	17	of	of	ADP
bjp-23039	177	18	the	the	DET
bjp-23039	177	19	pathway	pathway	NOUN
bjp-23039	177	20	was	be	AUX
bjp-23039	177	21	found	find	VERB
bjp-23039	177	22	to	to	PART
bjp-23039	177	23	be	be	AUX
bjp-23039	177	24	down	down	ADV
bjp-23039	177	25	-	-	PUNCT
bjp-23039	177	26	regulated	regulate	VERB
bjp-23039	177	27	in	in	ADP
bjp-23039	177	28	u2	u2	NOUN
bjp-23039	177	29	-	-	PUNCT
bjp-23039	177	30	os	os	NOUN
bjp-23039	177	31	cells	cell	NOUN
bjp-23039	177	32	not	not	PART
bjp-23039	177	33	exposed	expose	VERB
bjp-23039	177	34	to	to	PART
bjp-23039	177	35	fisetin	fisetin	VERB
bjp-23039	177	36	(	(	PUNCT
bjp-23039	177	37	figure	figure	NOUN
bjp-23039	177	38	5	5	NUM
bjp-23039	177	39	)	)	PUNCT
bjp-23039	177	40	.	.	PUNCT
bjp-23039	178	1	however	however	ADV
bjp-23039	178	2	,	,	PUNCT
bjp-23039	178	3	fisetin	fisetin	VERB
bjp-23039	178	4	at	at	ADP
bjp-23039	178	5	various	various	ADJ
bjp-23039	178	6	concentrations	concentration	NOUN
bjp-23039	178	7	(	(	PUNCT
bjp-23039	178	8	20	20	NUM
bjp-23039	178	9	-	-	SYM
bjp-23039	178	10	100	100	NUM
bjp-23039	178	11	µm	µm	NOUN
bjp-23039	178	12	)	)	PUNCT
bjp-23039	178	13	caused	cause	VERB
bjp-23039	178	14	a	a	DET
bjp-23039	178	15	significant	significant	ADJ
bjp-23039	178	16	(	(	PUNCT
bjp-23039	178	17	p<0.05	p<0.05	NOUN
bjp-23039	178	18	)	)	PUNCT
bjp-23039	178	19	decrease	decrease	NOUN
bjp-23039	178	20	in	in	ADP
bjp-23039	178	21	the	the	DET
bjp-23039	178	22	level	level	NOUN
bjp-23039	178	23	of	of	ADP
bjp-23039	178	24	p	p	PROPN
bjp-23039	178	25	-	-	PUNCT
bjp-23039	178	26	akt	akt	PROPN
bjp-23039	178	27	and	and	CCONJ
bjp-23039	178	28	mtorc1	mtorc1	NOUN
bjp-23039	178	29	(	(	PUNCT
bjp-23039	178	30	an	an	DET
bjp-23039	178	31	important	important	ADJ
bjp-23039	178	32	effector	effector	NOUN
bjp-23039	178	33	protein	protein	NOUN
bjp-23039	178	34	of	of	ADP
bjp-23039	178	35	akt	akt	PROPN
bjp-23039	178	36	)	)	PUNCT
bjp-23039	178	37	,	,	PUNCT
bjp-23039	178	38	while	while	SCONJ
bjp-23039	178	39	up	up	ADV
bjp-23039	178	40	-	-	PUNCT
bjp-23039	178	41	regulated	regulate	VERB
bjp-23039	178	42	pten	pten	NOUN
bjp-23039	178	43	.	.	PUNCT
bjp-23039	179	1	level	level	NOUN
bjp-23039	179	2	of	of	ADP
bjp-23039	179	3	phosphorylated	phosphorylate	VERB
bjp-23039	179	4	glycogensynthase	glycogensynthase	NOUN
bjp-23039	179	5	kinase	kinase	PROPN
bjp-23039	179	6	3β	3β	NUM
bjp-23039	179	7	(	(	PUNCT
bjp-23039	179	8	gsk3β	gsk3β	PROPN
bjp-23039	179	9	)	)	PUNCT
bjp-23039	179	10	,	,	PUNCT
bjp-23039	179	11	(	(	PUNCT
bjp-23039	179	12	a	a	DET
bjp-23039	179	13	serine	serine	NOUN
bjp-23039	179	14	/	/	SYM
bjp-23039	179	15	threonine	threonine	ADJ
bjp-23039	179	16	kinase	kinase	NOUN
bjp-23039	179	17	)	)	PUNCT
bjp-23039	179	18	and	and	CCONJ
bjp-23039	179	19	cyclin	cyclin	NOUN
bjp-23039	179	20	d1	d1	PROPN
bjp-23039	179	21	were	be	AUX
bjp-23039	179	22	potentially	potentially	ADV
bjp-23039	179	23	decreased	decrease	VERB
bjp-23039	179	24	by	by	ADP
bjp-23039	179	25	fisetin	fisetin	NOUN
bjp-23039	179	26	which	which	PRON
bjp-23039	179	27	is	be	AUX
bjp-23039	179	28	in	in	ADP
bjp-23039	179	29	line	line	NOUN
bjp-23039	179	30	with	with	ADP
bjp-23039	179	31	raised	raise	VERB
bjp-23039	179	32	non	non	ADJ
bjp-23039	179	33	-	-	ADJ
bjp-23039	179	34	phosphorylated	phosphorylated	ADJ
bjp-23039	179	35	levels	level	NOUN
bjp-23039	179	36	of	of	ADP
bjp-23039	179	37	gsk3β	gsk3β	PROPN
bjp-23039	179	38	.	.	PUNCT
bjp-23039	180	1	another	another	DET
bjp-23039	180	2	important	important	ADJ
bjp-23039	180	3	target	target	NOUN
bjp-23039	180	4	activated	activate	VERB
bjp-23039	180	5	by	by	ADP
bjp-23039	180	6	akt	akt	PROPN
bjp-23039	180	7	is	be	AUX
bjp-23039	180	8	nuclear	nuclear	ADJ
bjp-23039	180	9	factor	factor	NOUN
bjp-23039	180	10	-	-	PUNCT
bjp-23039	180	11	κb	κb	PROPN
bjp-23039	180	12	(	(	PUNCT
bjp-23039	180	13	nf	nf	NOUN
bjp-23039	180	14	-	-	PUNCT
bjp-23039	180	15	κb	κb	NOUN
bjp-23039	180	16	)	)	PUNCT
bjp-23039	180	17	,	,	PUNCT
bjp-23039	180	18	the	the	DET
bjp-23039	180	19	levels	level	NOUN
bjp-23039	180	20	of	of	ADP
bjp-23039	180	21	which	which	PRON
bjp-23039	180	22	are	be	AUX
bjp-23039	180	23	raised	raise	VERB
bjp-23039	180	24	in	in	ADP
bjp-23039	180	25	os	os	NOUN
bjp-23039	180	26	cells	cell	NOUN
bjp-23039	180	27	.	.	PUNCT
bjp-23039	181	1	down	down	ADP
bjp-23039	181	2	-	-	PUNCT
bjp-23039	181	3	regualtion	regualtion	NOUN
bjp-23039	181	4	of	of	ADP
bjp-23039	181	5	nf	nf	NOUN
bjp-23039	181	6	-	-	PUNCT
bjp-23039	181	7	κb	κb	NOUN
bjp-23039	181	8	along	along	ADP
bjp-23039	181	9	with	with	ADP
bjp-23039	181	10	significant	significant	ADJ
bjp-23039	181	11	up	up	NOUN
bjp-23039	181	12	-	-	PUNCT
bjp-23039	181	13	regulations	regulation	NOUN
bjp-23039	181	14	in	in	ADP
bjp-23039	181	15	iκb	iκb	NOUN
bjp-23039	181	16	upon	upon	SCONJ
bjp-23039	181	17	fisetin	fisetin	ADJ
bjp-23039	181	18	treatment	treatment	NOUN
bjp-23039	181	19	correlates	correlate	VERB
bjp-23039	181	20	with	with	ADP
bjp-23039	181	21	the	the	DET
bjp-23039	181	22	down	down	NOUN
bjp-23039	181	23	-	-	PUNCT
bjp-23039	181	24	regulation	regulation	NOUN
bjp-23039	181	25	of	of	ADP
bjp-23039	181	26	p	p	PROPN
bjp-23039	181	27	-	-	PUNCT
bjp-23039	181	28	akt	akt	PROPN
bjp-23039	181	29	levels	level	NOUN
bjp-23039	181	30	.	.	PUNCT
bjp-23039	182	1	these	these	DET
bjp-23039	182	2	observations	observation	NOUN
bjp-23039	182	3	suggest	suggest	VERB
bjp-23039	182	4	the	the	DET
bjp-23039	182	5	effective	effective	ADJ
bjp-23039	182	6	blocking	blocking	NOUN
bjp-23039	182	7	of	of	ADP
bjp-23039	182	8	the	the	DET
bjp-23039	182	9	pi3k/	pi3k/	NOUN
bjp-23039	182	10	akt	akt	PROPN
bjp-23039	182	11	pathway	pathway	NOUN
bjp-23039	182	12	,	,	PUNCT
bjp-23039	182	13	an	an	DET
bjp-23039	182	14	important	important	ADJ
bjp-23039	182	15	target	target	NOUN
bjp-23039	182	16	in	in	ADP
bjp-23039	182	17	cancer	cancer	NOUN
bjp-23039	182	18	therapy	therapy	NOUN
bjp-23039	182	19	.	.	PUNCT
bjp-23039	183	1	influence	influence	NOUN
bjp-23039	183	2	of	of	ADP
bjp-23039	183	3	fisetin	fisetin	NOUN
bjp-23039	183	4	on	on	ADP
bjp-23039	183	5	generation	generation	NOUN
bjp-23039	183	6	of	of	ADP
bjp-23039	183	7	ros	ros	PROPN
bjp-23039	183	8	it	it	PRON
bjp-23039	183	9	is	be	AUX
bjp-23039	183	10	well	well	ADV
bjp-23039	183	11	documented	document	VERB
bjp-23039	183	12	that	that	SCONJ
bjp-23039	183	13	excessive	excessive	ADJ
bjp-23039	183	14	generation	generation	NOUN
bjp-23039	183	15	of	of	ADP
bjp-23039	183	16	ros	ros	PROPN
bjp-23039	183	17	could	could	AUX
bjp-23039	183	18	interfere	interfere	VERB
bjp-23039	183	19	with	with	ADP
bjp-23039	183	20	dna	dna	PROPN
bjp-23039	183	21	,	,	PUNCT
bjp-23039	183	22	lipids	lipid	NOUN
bjp-23039	183	23	and	and	CCONJ
bjp-23039	183	24	proteins	protein	NOUN
bjp-23039	183	25	and	and	CCONJ
bjp-23039	183	26	cause	cause	VERB
bjp-23039	183	27	cellular	cellular	ADJ
bjp-23039	183	28	damage	damage	NOUN
bjp-23039	183	29	(	(	PUNCT
bjp-23039	183	30	simon	simon	PROPN
bjp-23039	183	31	et	et	PROPN
bjp-23039	183	32	al	al	PROPN
bjp-23039	183	33	.	.	PROPN
bjp-23039	183	34	,	,	PUNCT
bjp-23039	183	35	2000	2000	NUM
bjp-23039	183	36	;	;	PUNCT
bjp-23039	183	37	chen	chen	PROPN
bjp-23039	183	38	et	et	PROPN
bjp-23039	183	39	al	al	PROPN
bjp-23039	183	40	.	.	PROPN
bjp-23039	183	41	,	,	PUNCT
bjp-23039	183	42	2007	2007	NUM
bjp-23039	183	43	)	)	PUNCT
bjp-23039	183	44	.	.	PUNCT
bjp-23039	184	1	u-2	u-2	PROPN
bjp-23039	184	2	os	os	PROPN
bjp-23039	184	3	cells	cell	NOUN
bjp-23039	184	4	presented	present	VERB
bjp-23039	184	5	raised	raise	VERB
bjp-23039	184	6	levels	level	NOUN
bjp-23039	184	7	of	of	ADP
bjp-23039	184	8	ros	ros	PROPN
bjp-23039	184	9	.	.	PROPN
bjp-23039	184	10	fisetin	fisetin	PROPN
bjp-23039	184	11	exposure	exposure	NOUN
bjp-23039	184	12	at	at	ADP
bjp-23039	184	13	various	various	ADJ
bjp-23039	184	14	concentrations	concentration	NOUN
bjp-23039	184	15	resulted	result	VERB
bjp-23039	184	16	in	in	ADP
bjp-23039	184	17	a	a	DET
bjp-23039	184	18	noticeable	noticeable	ADJ
bjp-23039	184	19	increase	increase	NOUN
bjp-23039	184	20	in	in	ADP
bjp-23039	184	21	ros	ros	PROPN
bjp-23039	184	22	levels	level	NOUN
bjp-23039	184	23	in	in	ADP
bjp-23039	184	24	a	a	DET
bjp-23039	184	25	dose	dose	NOUN
bjp-23039	184	26	-	-	PUNCT
bjp-23039	184	27	dependent	dependent	ADJ
bjp-23039	184	28	way	way	NOUN
bjp-23039	184	29	(	(	PUNCT
bjp-23039	184	30	figure	figure	NOUN
bjp-23039	184	31	6	6	NUM
bjp-23039	184	32	)	)	PUNCT
bjp-23039	184	33	.	.	PUNCT
bjp-23039	185	1	this	this	DET
bjp-23039	185	2	increase	increase	NOUN
bjp-23039	185	3	though	though	SCONJ
bjp-23039	185	4	observable	observable	ADJ
bjp-23039	185	5	,	,	PUNCT
bjp-23039	185	6	was	be	AUX
bjp-23039	185	7	not	not	PART
bjp-23039	185	8	significant	significant	ADJ
bjp-23039	185	9	.	.	PUNCT
bjp-23039	186	1	fisetin	fisetin	ADJ
bjp-23039	186	2	modulates	modulate	NOUN
bjp-23039	186	3	the	the	DET
bjp-23039	186	4	erk	erk	PROPN
bjp-23039	186	5	/	/	SYM
bjp-23039	186	6	jnk	jnk	PROPN
bjp-23039	186	7	/	/	SYM
bjp-23039	186	8	p38mapk	p38mapk	PROPN
bjp-23039	186	9	signalling	signal	VERB
bjp-23039	186	10	cascade	cascade	NOUN
bjp-23039	186	11	as	as	ADP
bjp-23039	186	12	mapks	mapks	NOUN
bjp-23039	186	13	are	be	AUX
bjp-23039	186	14	important	important	ADJ
bjp-23039	186	15	regulators	regulator	NOUN
bjp-23039	186	16	of	of	ADP
bjp-23039	186	17	stress	stress	NOUN
bjp-23039	186	18	responses	response	NOUN
bjp-23039	186	19	including	include	VERB
bjp-23039	186	20	the	the	DET
bjp-23039	186	21	induction	induction	NOUN
bjp-23039	186	22	of	of	ADP
bjp-23039	186	23	apoptosis	apoptosis	NOUN
bjp-23039	186	24	(	(	PUNCT
bjp-23039	186	25	johnson	johnson	PROPN
bjp-23039	186	26	and	and	CCONJ
bjp-23039	186	27	lapadat	lapadat	PROPN
bjp-23039	186	28	,	,	PUNCT
bjp-23039	186	29	2002	2002	NUM
bjp-23039	186	30	)	)	PUNCT
bjp-23039	187	1	we	we	PRON
bjp-23039	187	2	assessed	assess	VERB
bjp-23039	187	3	the	the	DET
bjp-23039	187	4	influence	influence	NOUN
bjp-23039	187	5	of	of	ADP
bjp-23039	187	6	fisetin	fisetin	NOUN
bjp-23039	187	7	over	over	ADP
bjp-23039	187	8	jnk	jnk	PROPN
bjp-23039	187	9	,	,	PUNCT
bjp-23039	187	10	erk1/2	erk1/2	PROPN
bjp-23039	187	11	and	and	CCONJ
bjp-23039	187	12	p38	p38	NOUN
bjp-23039	187	13	expression	expression	NOUN
bjp-23039	187	14	level	level	NOUN
bjp-23039	187	15	.	.	PUNCT
bjp-23039	188	1	significant	significant	ADJ
bjp-23039	188	2	upregulation	upregulation	NOUN
bjp-23039	188	3	in	in	ADP
bjp-23039	188	4	the	the	DET
bjp-23039	188	5	phosphorylated	phosphorylate	VERB
bjp-23039	188	6	levels	level	NOUN
bjp-23039	188	7	of	of	ADP
bjp-23039	188	8	jnk	jnk	PROPN
bjp-23039	188	9	was	be	AUX
bjp-23039	188	10	observed	observe	VERB
bjp-23039	188	11	(	(	PUNCT
bjp-23039	188	12	figure	figure	NOUN
bjp-23039	188	13	7	7	NUM
bjp-23039	188	14	)	)	PUNCT
bjp-23039	188	15	.	.	PUNCT
bjp-23039	189	1	incubation	incubation	NOUN
bjp-23039	189	2	of	of	ADP
bjp-23039	189	3	os	os	NOUN
bjp-23039	189	4	cells	cell	NOUN
bjp-23039	189	5	in	in	ADP
bjp-23039	189	6	the	the	DET
bjp-23039	189	7	presence	presence	NOUN
bjp-23039	189	8	of	of	ADP
bjp-23039	189	9	fisetin	fisetin	NOUN
bjp-23039	189	10	(	(	PUNCT
bjp-23039	189	11	20	20	NUM
bjp-23039	189	12	-	-	SYM
bjp-23039	189	13	100	100	NUM
bjp-23039	189	14	µm	µm	NOUN
bjp-23039	189	15	)	)	PUNCT
bjp-23039	189	16	considerably	considerably	ADV
bjp-23039	189	17	(	(	PUNCT
bjp-23039	189	18	p<0.05	p<0.05	NOUN
bjp-23039	189	19	)	)	PUNCT
bjp-23039	189	20	down	down	ADV
bjp-23039	189	21	-	-	PUNCT
bjp-23039	189	22	regulated	regulate	VERB
bjp-23039	189	23	the	the	DET
bjp-23039	189	24	activation	activation	NOUN
bjp-23039	189	25	and	and	CCONJ
bjp-23039	189	26	decreased	decrease	VERB
bjp-23039	189	27	the	the	DET
bjp-23039	189	28	levels	level	NOUN
bjp-23039	189	29	of	of	ADP
bjp-23039	189	30	perk1/2	perk1/2	PROPN
bjp-23039	189	31	and	and	CCONJ
bjp-23039	189	32	erk1/2	erk1/2	PROPN
bjp-23039	189	33	as	as	ADV
bjp-23039	189	34	well	well	ADV
bjp-23039	189	35	.	.	PUNCT
bjp-23039	190	1	however	however	ADV
bjp-23039	190	2	,	,	PUNCT
bjp-23039	190	3	higher	high	ADJ
bjp-23039	190	4	expression	expression	NOUN
bjp-23039	190	5	of	of	ADP
bjp-23039	190	6	phosphorylated	phosphorylate	VERB
bjp-23039	190	7	p38	p38	NOUN
bjp-23039	190	8	was	be	AUX
bjp-23039	190	9	observed	observe	VERB
bjp-23039	190	10	.	.	PUNCT
bjp-23039	191	1	further	far	ADV
bjp-23039	191	2	,	,	PUNCT
bjp-23039	191	3	fisetin	fisetin	VERB
bjp-23039	191	4	brought	bring	VERB
bjp-23039	191	5	multi	multi	ADJ
bjp-23039	191	6	-	-	ADJ
bjp-23039	191	7	fold	fold	ADJ
bjp-23039	191	8	raise	raise	NOUN
bjp-23039	191	9	in	in	ADP
bjp-23039	191	10	the	the	DET
bjp-23039	191	11	levels	level	NOUN
bjp-23039	191	12	of	of	ADP
bjp-23039	191	13	p	p	PROPN
bjp-23039	191	14	-	-	PUNCT
bjp-23039	191	15	c	c	NOUN
bjp-23039	191	16	-	-	PUNCT
bjp-23039	191	17	jun	jun	PROPN
bjp-23039	191	18	.	.	PROPN
bjp-23039	192	1	while	while	SCONJ
bjp-23039	192	2	20	20	NUM
bjp-23039	192	3	-	-	SYM
bjp-23039	192	4	60	60	NUM
bjp-23039	192	5	µm	µm	NOUN
bjp-23039	192	6	of	of	ADP
bjp-23039	192	7	fisetin	fisetin	NOUN
bjp-23039	192	8	was	be	AUX
bjp-23039	192	9	effective	effective	ADJ
bjp-23039	192	10	in	in	ADP
bjp-23039	192	11	decreasing	decrease	VERB
bjp-23039	192	12	the	the	DET
bjp-23039	192	13	expression	expression	NOUN
bjp-23039	192	14	of	of	ADP
bjp-23039	192	15	the	the	DET
bjp-23039	192	16	phosphorylated	phosphorylate	VERB
bjp-23039	192	17	forms	form	NOUN
bjp-23039	192	18	of	of	ADP
bjp-23039	192	19	erk1/2	erk1/2	PROPN
bjp-23039	192	20	,	,	PUNCT
bjp-23039	192	21	100	100	NUM
bjp-23039	192	22	µm	µm	NOUN
bjp-23039	192	23	fisetin	fisetin	NOUN
bjp-23039	192	24	presented	present	VERB
bjp-23039	192	25	additional	additional	ADJ
bjp-23039	192	26	downregulation	downregulation	NOUN
bjp-23039	192	27	.	.	PUNCT
bjp-23039	193	1	discussion	discussion	NOUN
bjp-23039	193	2	most	most	ADJ
bjp-23039	193	3	cancer	cancer	NOUN
bjp-23039	193	4	therapeutic	therapeutic	ADJ
bjp-23039	193	5	regimens	regimen	NOUN
bjp-23039	193	6	including	include	VERB
bjp-23039	193	7	chemotherapy	chemotherapy	NOUN
bjp-23039	193	8	,	,	PUNCT
bjp-23039	193	9	inhibit	inhibit	VERB
bjp-23039	193	10	tumors	tumor	NOUN
bjp-23039	193	11	by	by	ADP
bjp-23039	193	12	activating	activate	VERB
bjp-23039	193	13	apoptosis	apoptosis	NOUN
bjp-23039	193	14	(	(	PUNCT
bjp-23039	193	15	zhang	zhang	PROPN
bjp-23039	193	16	et	et	PROPN
bjp-23039	193	17	al	al	PROPN
bjp-23039	193	18	.	.	PROPN
bjp-23039	193	19	,	,	PUNCT
bjp-23039	193	20	2013	2013	NUM
bjp-23039	193	21	)	)	PUNCT
bjp-23039	193	22	.	.	PUNCT
bjp-23039	194	1	in	in	ADP
bjp-23039	194	2	our	our	PRON
bjp-23039	194	3	study	study	NOUN
bjp-23039	194	4	,	,	PUNCT
bjp-23039	194	5	dietary	dietary	ADJ
bjp-23039	194	6	flavonoid	flavonoid	NOUN
bjp-23039	194	7	,	,	PUNCT
bjp-23039	194	8	fisetin	fisetin	VERB
bjp-23039	194	9	at	at	ADP
bjp-23039	194	10	concentrations	concentration	NOUN
bjp-23039	194	11	20	20	NUM
bjp-23039	194	12	-	-	SYM
bjp-23039	194	13	100	100	NUM
bjp-23039	194	14	µm	µm	ADP
bjp-23039	194	15	induced	induce	VERB
bjp-23039	194	16	a	a	DET
bjp-23039	194	17	decrease	decrease	NOUN
bjp-23039	194	18	in	in	ADP
bjp-23039	194	19	the	the	DET
bjp-23039	194	20	viability	viability	NOUN
bjp-23039	194	21	of	of	ADP
bjp-23039	194	22	u-2	u-2	PROPN
bjp-23039	194	23	os	os	PROPN
bjp-23039	194	24	cells	cell	NOUN
bjp-23039	194	25	.	.	PUNCT
bjp-23039	195	1	further	far	ADV
bjp-23039	195	2	,	,	PUNCT
bjp-23039	195	3	increase	increase	VERB
bjp-23039	195	4	in	in	ADP
bjp-23039	195	5	apoptotic	apoptotic	ADJ
bjp-23039	195	6	cell	cell	NOUN
bjp-23039	195	7	counts	count	NOUN
bjp-23039	195	8	were	be	AUX
bjp-23039	195	9	observed	observe	VERB
bjp-23039	195	10	following	follow	VERB
bjp-23039	195	11	fisetin	fisetin	ADJ
bjp-23039	195	12	exposure	exposure	NOUN
bjp-23039	195	13	as	as	SCONJ
bjp-23039	195	14	determined	determine	VERB
bjp-23039	195	15	by	by	ADP
bjp-23039	195	16	annexin	annexin	NOUN
bjp-23039	195	17	-	-	PUNCT
bjp-23039	195	18	v	v	NOUN
bjp-23039	195	19	/	/	SYM
bjp-23039	195	20	pi	pi	NOUN
bjp-23039	195	21	staining	stain	VERB
bjp-23039	195	22	.	.	PUNCT
bjp-23039	196	1	mitochondria	mitochondria	PROPN
bjp-23039	196	2	play	play	VERB
bjp-23039	196	3	a	a	DET
bjp-23039	196	4	crucial	crucial	ADJ
bjp-23039	196	5	role	role	NOUN
bjp-23039	196	6	in	in	ADP
bjp-23039	196	7	apoptosis	apoptosis	NOUN
bjp-23039	196	8	(	(	PUNCT
bjp-23039	196	9	vanloo	vanloo	NOUN
bjp-23039	196	10	et	et	PROPN
bjp-23039	196	11	al	al	PROPN
bjp-23039	196	12	.	.	PROPN
bjp-23039	196	13	,	,	PUNCT
bjp-23039	196	14	2002	2002	NUM
bjp-23039	196	15	)	)	PUNCT
bjp-23039	196	16	.	.	PUNCT
bjp-23039	197	1	disruption	disruption	NOUN
bjp-23039	197	2	of	of	ADP
bjp-23039	197	3	mitochondrial	mitochondrial	ADJ
bjp-23039	197	4	integrity	integrity	NOUN
bjp-23039	197	5	has	have	AUX
bjp-23039	197	6	been	be	AUX
bjp-23039	197	7	established	establish	VERB
bjp-23039	197	8	as	as	ADP
bjp-23039	197	9	one	one	NUM
bjp-23039	197	10	of	of	ADP
bjp-23039	197	11	the	the	DET
bjp-23039	197	12	earliest	early	ADJ
bjp-23039	197	13	intracellular	intracellular	ADJ
bjp-23039	197	14	events	event	NOUN
bjp-23039	197	15	that	that	PRON
bjp-23039	197	16	occur	occur	VERB
bjp-23039	197	17	following	follow	VERB
bjp-23039	197	18	initiation	initiation	NOUN
bjp-23039	197	19	of	of	ADP
bjp-23039	197	20	apoptosis	apoptosis	NOUN
bjp-23039	197	21	(	(	PUNCT
bjp-23039	197	22	qi	qi	X
bjp-23039	197	23	et	et	NOUN
bjp-23039	197	24	al	al	PROPN
bjp-23039	197	25	.	.	PROPN
bjp-23039	197	26	,	,	PUNCT
bjp-23039	197	27	2010	2010	NUM
bjp-23039	197	28	)	)	PUNCT
bjp-23039	197	29	.	.	PUNCT
bjp-23039	198	1	decreases	decrease	NOUN
bjp-23039	198	2	in	in	ADP
bjp-23039	198	3	the	the	DET
bjp-23039	198	4	mitochondrial	mitochondrial	ADJ
bjp-23039	198	5	transmembrane	transmembrane	NOUN
bjp-23039	198	6	potential	potential	NOUN
bjp-23039	198	7	(	(	PUNCT
bjp-23039	198	8	δψm	δψm	PROPN
bjp-23039	198	9	,	,	PUNCT
bjp-23039	198	10	)	)	PUNCT
bjp-23039	198	11	is	be	AUX
bjp-23039	198	12	associated	associate	VERB
bjp-23039	198	13	with	with	ADP
bjp-23039	198	14	mitochondrial	mitochondrial	ADJ
bjp-23039	198	15	dysfunction	dysfunction	NOUN
bjp-23039	198	16	,	,	PUNCT
bjp-23039	198	17	that	that	PRON
bjp-23039	198	18	activates	activate	VERB
bjp-23039	198	19	the	the	DET
bjp-23039	198	20	efflux	efflux	NOUN
bjp-23039	198	21	of	of	ADP
bjp-23039	198	22	cytochrome	cytochrome	PROPN
bjp-23039	198	23	c	c	NOUN
bjp-23039	198	24	to	to	PART
bjp-23039	198	25	figure	figure	VERB
bjp-23039	198	26	6	6	NUM
bjp-23039	198	27	.	.	PUNCT
bjp-23039	199	1	influence	influence	NOUN
bjp-23039	199	2	of	of	ADP
bjp-23039	199	3	fisetin	fisetin	NOUN
bjp-23039	199	4	on	on	ADP
bjp-23039	199	5	intracellular	intracellular	ADJ
bjp-23039	199	6	ros	ros	NOUN
bjp-23039	199	7	generation	generation	NOUN
bjp-23039	199	8	in	in	ADP
bjp-23039	199	9	u-2	u-2	PROPN
bjp-23039	199	10	os	os	PROPN
bjp-23039	199	11	cancer	cancer	NOUN
bjp-23039	199	12	cells	cell	NOUN
bjp-23039	199	13	values	value	NOUN
bjp-23039	199	14	are	be	AUX
bjp-23039	199	15	represented	represent	VERB
bjp-23039	199	16	as	as	ADP
bjp-23039	199	17	mean	mean	NOUN
bjp-23039	199	18	±	±	NUM
bjp-23039	199	19	sd	sd	NOUN
bjp-23039	199	20	;	;	PUNCT
bjp-23039	199	21	n=3	n=3	X
bjp-23039	199	22	.	.	NOUN
bjp-23039	200	1	*	*	PUNCT
bjp-23039	200	2	represents	represent	VERB
bjp-23039	200	3	p<0.05	p<0.05	NOUN
bjp-23039	200	4	compared	compare	VERB
bjp-23039	200	5	with	with	ADP
bjp-23039	200	6	control	control	NOUN
bjp-23039	200	7	as	as	SCONJ
bjp-23039	200	8	determined	determine	VERB
bjp-23039	200	9	by	by	ADP
bjp-23039	200	10	one	one	NUM
bjp-23039	200	11	-	-	PUNCT
bjp-23039	200	12	way	way	NOUN
bjp-23039	200	13	anova	anova	PROPN
bjp-23039	200	14	200	200	NUM
bjp-23039	200	15	150	150	NUM
bjp-23039	200	16	100	100	NUM
bjp-23039	200	17	50	50	NUM
bjp-23039	200	18	0	0	NUM
bjp-23039	201	1	r	r	NOUN
bjp-23039	201	2	o	o	NOUN
bjp-23039	201	3	s	s	X
bjp-23039	201	4	g	g	NOUN
bjp-23039	201	5	en	en	INTJ
bjp-23039	201	6	er	er	INTJ
bjp-23039	201	7	at	at	ADP
bjp-23039	201	8	io	io	X
bjp-23039	201	9	n	n	PROPN
bjp-23039	201	10	(	(	PUNCT
bjp-23039	201	11	%	%	INTJ
bjp-23039	201	12	o	o	X
bjp-23039	201	13	f	f	X
bjp-23039	201	14	c	c	NOUN
bjp-23039	201	15	on	on	ADP
bjp-23039	201	16	tro	tro	X
bjp-23039	201	17	l	l	NOUN
bjp-23039	201	18	)	)	PUNCT
bjp-23039	201	19	0	0	NUM
bjp-23039	201	20	20	20	NUM
bjp-23039	201	21	40	40	NUM
bjp-23039	201	22	60	60	NUM
bjp-23039	201	23	80	80	NUM
bjp-23039	201	24	100	100	NUM
bjp-23039	201	25	fisetin	fisetin	NOUN
bjp-23039	201	26	(	(	PUNCT
bjp-23039	201	27	µm	µm	NOUN
bjp-23039	201	28	)	)	PUNCT
bjp-23039	201	29	*	*	PUNCT
bjp-23039	202	1	*	*	PUNCT
bjp-23039	202	2	12	12	NUM
bjp-23039	202	3	hours	hour	NOUN
bjp-23039	202	4	24	24	NUM
bjp-23039	202	5	hours	hour	NOUN
bjp-23039	202	6	*	*	PUNCT
bjp-23039	203	1	*	*	PUNCT
bjp-23039	203	2	*	*	PUNCT
bjp-23039	203	3	*	*	PUNCT
bjp-23039	203	4	bangladesh	bangladesh	PROPN
bjp-23039	203	5	j	j	PROPN
bjp-23039	203	6	pharmacol	pharmacol	PROPN
bjp-23039	203	7	2015	2015	NUM
bjp-23039	203	8	;	;	PUNCT
bjp-23039	203	9	10	10	NUM
bjp-23039	203	10	:	:	SYM
bjp-23039	203	11	820	820	NUM
bjp-23039	203	12	-	-	SYM
bjp-23039	203	13	829	829	NUM
bjp-23039	203	14	825	825	NUM
bjp-23039	203	15	a	a	DET
bjp-23039	203	16	the	the	DET
bjp-23039	203	17	cytosol	cytosol	NOUN
bjp-23039	203	18	and	and	CCONJ
bjp-23039	203	19	initiates	initiate	VERB
bjp-23039	203	20	the	the	DET
bjp-23039	203	21	caspase	caspase	NOUN
bjp-23039	203	22	cascade	cascade	NOUN
bjp-23039	203	23	leading	lead	VERB
bjp-23039	203	24	to	to	ADP
bjp-23039	203	25	apoptosis	apoptosis	NOUN
bjp-23039	203	26	(	(	PUNCT
bjp-23039	203	27	han	han	PROPN
bjp-23039	203	28	et	et	PROPN
bjp-23039	203	29	al	al	PROPN
bjp-23039	203	30	.	.	PROPN
bjp-23039	203	31	,	,	PUNCT
bjp-23039	203	32	2006	2006	NUM
bjp-23039	203	33	;	;	PUNCT
bjp-23039	203	34	kroemer	kroemer	PROPN
bjp-23039	203	35	et	et	PROPN
bjp-23039	203	36	al	al	PROPN
bjp-23039	203	37	.	.	PROPN
bjp-23039	203	38	,	,	PUNCT
bjp-23039	203	39	2007	2007	NUM
bjp-23039	203	40	)	)	PUNCT
bjp-23039	203	41	.	.	PUNCT
bjp-23039	204	1	therefore	therefore	ADV
bjp-23039	204	2	,	,	PUNCT
bjp-23039	204	3	the	the	DET
bjp-23039	204	4	observed	observed	ADJ
bjp-23039	204	5	decrease	decrease	NOUN
bjp-23039	204	6	of	of	ADP
bjp-23039	204	7	δψm	δψm	NOUN
bjp-23039	204	8	following	follow	VERB
bjp-23039	204	9	treatment	treatment	NOUN
bjp-23039	204	10	with	with	ADP
bjp-23039	204	11	fisetin	fisetin	NOUN
bjp-23039	204	12	,	,	PUNCT
bjp-23039	204	13	suggests	suggest	VERB
bjp-23039	204	14	mitochondrial	mitochondrial	ADJ
bjp-23039	204	15	dysfunction	dysfunction	NOUN
bjp-23039	204	16	and	and	CCONJ
bjp-23039	204	17	disruption	disruption	NOUN
bjp-23039	204	18	in	in	ADP
bjp-23039	204	19	mitochondrial	mitochondrial	ADJ
bjp-23039	204	20	integrity	integrity	NOUN
bjp-23039	204	21	that	that	PRON
bjp-23039	204	22	could	could	AUX
bjp-23039	204	23	have	have	VERB
bjp-23039	204	24	possibility	possibility	NOUN
bjp-23039	204	25	be	be	AUX
bjp-23039	204	26	responsible	responsible	ADJ
bjp-23039	204	27	for	for	ADP
bjp-23039	204	28	the	the	DET
bjp-23039	204	29	raised	raise	VERB
bjp-23039	204	30	apoptotic	apoptotic	ADJ
bjp-23039	204	31	cell	cell	NOUN
bjp-23039	204	32	counts	count	NOUN
bjp-23039	204	33	.	.	PUNCT
bjp-23039	205	1	to	to	PART
bjp-23039	205	2	assess	assess	VERB
bjp-23039	205	3	the	the	DET
bjp-23039	205	4	activation	activation	NOUN
bjp-23039	205	5	of	of	ADP
bjp-23039	205	6	caspase	caspase	PROPN
bjp-23039	205	7	cascade	cascade	NOUN
bjp-23039	205	8	,	,	PUNCT
bjp-23039	205	9	expression	expression	NOUN
bjp-23039	205	10	levels	level	NOUN
bjp-23039	205	11	of	of	ADP
bjp-23039	205	12	caspases-9	caspases-9	PROPN
bjp-23039	205	13	,	,	PUNCT
bjp-23039	205	14	-8	-8	NOUN
bjp-23039	205	15	and	and	CCONJ
bjp-23039	205	16	-3	-3	PUNCT
bjp-23039	205	17	were	be	AUX
bjp-23039	205	18	determined	determine	VERB
bjp-23039	205	19	.	.	PUNCT
bjp-23039	206	1	activation	activation	NOUN
bjp-23039	206	2	of	of	ADP
bjp-23039	206	3	caspase-9	caspase-9	PROPN
bjp-23039	206	4	and	and	CCONJ
bjp-23039	206	5	-8	-8	NOUN
bjp-23039	206	6	suggests	suggest	VERB
bjp-23039	206	7	the	the	DET
bjp-23039	206	8	involvement	involvement	NOUN
bjp-23039	206	9	of	of	ADP
bjp-23039	206	10	both	both	CCONJ
bjp-23039	206	11	intrinsic	intrinsic	ADJ
bjp-23039	206	12	and	and	CCONJ
bjp-23039	206	13	extrinsic	extrinsic	ADJ
bjp-23039	206	14	pathways	pathway	NOUN
bjp-23039	206	15	of	of	ADP
bjp-23039	206	16	apoptosis	apoptosis	NOUN
bjp-23039	206	17	that	that	PRON
bjp-23039	206	18	sequentially	sequentially	ADV
bjp-23039	206	19	lead	lead	VERB
bjp-23039	206	20	to	to	ADP
bjp-23039	206	21	the	the	DET
bjp-23039	206	22	activation	activation	NOUN
bjp-23039	206	23	of	of	ADP
bjp-23039	206	24	caspase-3	caspase-3	PUNCT
bjp-23039	206	25	(	(	PUNCT
bjp-23039	206	26	hartojo	hartojo	ADV
bjp-23039	206	27	et	et	PROPN
bjp-23039	206	28	al	al	PROPN
bjp-23039	206	29	.	.	PROPN
bjp-23039	206	30	,	,	PUNCT
bjp-23039	206	31	2010	2010	NUM
bjp-23039	206	32	)	)	PUNCT
bjp-23039	206	33	.	.	PUNCT
bjp-23039	207	1	fisetin	fisetin	PROPN
bjp-23039	207	2	was	be	AUX
bjp-23039	207	3	observed	observe	VERB
bjp-23039	207	4	to	to	PART
bjp-23039	207	5	cause	cause	VERB
bjp-23039	207	6	dosedependent	dosedependent	NOUN
bjp-23039	207	7	multifold	multifold	ADJ
bjp-23039	207	8	activation	activation	NOUN
bjp-23039	207	9	of	of	ADP
bjp-23039	207	10	caspase-3	caspase-3	NUM
bjp-23039	207	11	,	,	PUNCT
bjp-23039	207	12	-8	-8	NOUN
bjp-23039	207	13	and	and	CCONJ
bjp-23039	207	14	-9	-9	INTJ
bjp-23039	207	15	.	.	PUNCT
bjp-23039	208	1	these	these	DET
bjp-23039	208	2	findings	finding	NOUN
bjp-23039	208	3	indicate	indicate	VERB
bjp-23039	208	4	that	that	SCONJ
bjp-23039	208	5	fisetin	fisetin	NOUN
bjp-23039	208	6	induces	induce	NOUN
bjp-23039	208	7	apoptosis	apoptosis	NOUN
bjp-23039	208	8	in	in	ADP
bjp-23039	208	9	human	human	ADJ
bjp-23039	208	10	osteosarcoma	osteosarcoma	ADJ
bjp-23039	208	11	cells	cell	NOUN
bjp-23039	208	12	by	by	ADP
bjp-23039	208	13	activating	activate	VERB
bjp-23039	208	14	caspase	caspase	PROPN
bjp-23039	208	15	cascades	cascade	NOUN
bjp-23039	208	16	.	.	PUNCT
bjp-23039	209	1	bcl-2	bcl-2	VERB
bjp-23039	209	2	family	family	NOUN
bjp-23039	209	3	proteins	protein	NOUN
bjp-23039	209	4	are	be	AUX
bjp-23039	209	5	involved	involve	VERB
bjp-23039	209	6	in	in	ADP
bjp-23039	209	7	the	the	DET
bjp-23039	209	8	regulation	regulation	NOUN
bjp-23039	209	9	of	of	ADP
bjp-23039	209	10	apoptosis	apoptosis	NOUN
bjp-23039	209	11	and	and	CCONJ
bjp-23039	209	12	mitochondrial	mitochondrial	ADJ
bjp-23039	209	13	membrane	membrane	NOUN
bjp-23039	209	14	potential	potential	NOUN
bjp-23039	209	15	(	(	PUNCT
bjp-23039	209	16	hunter	hunter	NOUN
bjp-23039	209	17	et	et	PROPN
bjp-23039	209	18	al	al	PROPN
bjp-23039	209	19	.	.	PROPN
bjp-23039	209	20	,	,	PUNCT
bjp-23039	209	21	2007	2007	NUM
bjp-23039	209	22	;	;	PUNCT
bjp-23039	209	23	heath	heath	PROPN
bjp-23039	209	24	-	-	PUNCT
bjp-23039	209	25	engel	engel	PROPN
bjp-23039	209	26	et	et	PROPN
bjp-23039	209	27	al	al	PROPN
bjp-23039	209	28	.	.	PROPN
bjp-23039	209	29	,	,	PUNCT
bjp-23039	209	30	2008	2008	NUM
bjp-23039	209	31	;	;	PUNCT
bjp-23039	209	32	gyrdhansen	gyrdhansen	NOUN
bjp-23039	209	33	and	and	CCONJ
bjp-23039	209	34	meier	meier	PROPN
bjp-23039	209	35	,	,	PUNCT
bjp-23039	209	36	2010	2010	NUM
bjp-23039	209	37	;	;	PUNCT
bjp-23039	209	38	huttemann	huttemann	PROPN
bjp-23039	209	39	et	et	PROPN
bjp-23039	209	40	al	al	PROPN
bjp-23039	209	41	.	.	PROPN
bjp-23039	209	42	,	,	PUNCT
bjp-23039	209	43	2011	2011	NUM
bjp-23039	209	44	)	)	PUNCT
bjp-23039	209	45	.	.	PUNCT
bjp-23039	210	1	the	the	DET
bjp-23039	210	2	pro	pro	ADJ
bjp-23039	210	3	-	-	ADJ
bjp-23039	210	4	apoptotic	apoptotic	ADJ
bjp-23039	210	5	bcl-2	bcl-2	VERB
bjp-23039	210	6	-	-	ADJ
bjp-23039	210	7	family	family	NOUN
bjp-23039	210	8	proteins	protein	NOUN
bjp-23039	210	9	such	such	ADJ
bjp-23039	210	10	as	as	ADP
bjp-23039	210	11	bax	bax	PROPN
bjp-23039	210	12	and	and	CCONJ
bjp-23039	210	13	bak	bak	PROPN
bjp-23039	210	14	form	form	VERB
bjp-23039	210	15	pores	pore	NOUN
bjp-23039	210	16	in	in	ADP
bjp-23039	210	17	the	the	DET
bjp-23039	210	18	outer	outer	ADJ
bjp-23039	210	19	mitochondrial	mitochondrial	ADJ
bjp-23039	210	20	membrane	membrane	NOUN
bjp-23039	210	21	and	and	CCONJ
bjp-23039	210	22	stimulate	stimulate	VERB
bjp-23039	210	23	apoptosis	apoptosis	NOUN
bjp-23039	210	24	,	,	PUNCT
bjp-23039	210	25	while	while	SCONJ
bjp-23039	210	26	the	the	DET
bjp-23039	210	27	antiapoptotic	antiapoptotic	ADJ
bjp-23039	210	28	proteins	protein	NOUN
bjp-23039	210	29	including	include	VERB
bjp-23039	210	30	bcl-2	bcl-2	NOUN
bjp-23039	210	31	and	and	CCONJ
bjp-23039	210	32	bcl	bcl	PROPN
bjp-23039	210	33	-	-	PROPN
bjp-23039	210	34	xl	xl	PROPN
bjp-23039	210	35	inhibit	inhibit	VERB
bjp-23039	210	36	pore	pore	ADJ
bjp-23039	210	37	formation	formation	NOUN
bjp-23039	210	38	(	(	PUNCT
bjp-23039	210	39	gross	gross	INTJ
bjp-23039	210	40	et	et	PROPN
bjp-23039	210	41	al	al	PROPN
bjp-23039	210	42	.	.	PROPN
bjp-23039	210	43	,	,	PUNCT
bjp-23039	210	44	1999	1999	NUM
bjp-23039	210	45	)	)	PUNCT
bjp-23039	210	46	.	.	PUNCT
bjp-23039	211	1	it	it	PRON
bjp-23039	211	2	has	have	AUX
bjp-23039	211	3	been	be	AUX
bjp-23039	211	4	demonstrated	demonstrate	VERB
bjp-23039	211	5	that	that	SCONJ
bjp-23039	211	6	bcl	bcl	PROPN
bjp-23039	211	7	-	-	PROPN
bjp-23039	211	8	xl	xl	PROPN
bjp-23039	211	9	figure	figure	NOUN
bjp-23039	211	10	7	7	NUM
bjp-23039	211	11	:	:	PUNCT
bjp-23039	211	12	fisetin	fisetin	NOUN
bjp-23039	211	13	regulates	regulate	VERB
bjp-23039	211	14	the	the	DET
bjp-23039	211	15	mapk	mapk	NOUN
bjp-23039	211	16	pathway	pathway	NOUN
bjp-23039	211	17	proteins	protein	NOUN
bjp-23039	211	18	(	(	PUNCT
bjp-23039	211	19	a	a	X
bjp-23039	211	20	)	)	PUNCT
bjp-23039	211	21	significant	significant	ADJ
bjp-23039	211	22	down	down	ADP
bjp-23039	211	23	regulations	regulation	NOUN
bjp-23039	211	24	of	of	ADP
bjp-23039	211	25	erk1/2	erk1/2	PROPN
bjp-23039	211	26	with	with	ADP
bjp-23039	211	27	marked	mark	VERB
bjp-23039	211	28	increase	increase	NOUN
bjp-23039	211	29	in	in	ADP
bjp-23039	211	30	the	the	DET
bjp-23039	211	31	expressions	expression	NOUN
bjp-23039	211	32	of	of	ADP
bjp-23039	211	33	jnk	jnk	PROPN
bjp-23039	211	34	and	and	CCONJ
bjp-23039	211	35	c	c	PROPN
bjp-23039	211	36	-	-	PUNCT
bjp-23039	211	37	jun	jun	PROPN
bjp-23039	211	38	were	be	AUX
bjp-23039	211	39	observed	observe	VERB
bjp-23039	211	40	following	follow	VERB
bjp-23039	211	41	fisetin	fisetin	NOUN
bjp-23039	211	42	exposure	exposure	NOUN
bjp-23039	211	43	.	.	PUNCT
bjp-23039	212	1	marked	mark	VERB
bjp-23039	212	2	up	up	ADP
bjp-23039	212	3	-	-	PUNCT
bjp-23039	212	4	regulations	regulation	NOUN
bjp-23039	212	5	in	in	ADP
bjp-23039	212	6	the	the	DET
bjp-23039	212	7	phosphorylated	phosphorylate	VERB
bjp-23039	212	8	forms	form	NOUN
bjp-23039	212	9	of	of	ADP
bjp-23039	212	10	jnk	jnk	PROPN
bjp-23039	212	11	,	,	PUNCT
bjp-23039	212	12	c	c	PROPN
bjp-23039	212	13	-	-	PUNCT
bjp-23039	212	14	jun	jun	PROPN
bjp-23039	212	15	and	and	CCONJ
bjp-23039	212	16	p38	p38	NOUN
bjp-23039	212	17	were	be	AUX
bjp-23039	212	18	also	also	ADV
bjp-23039	212	19	observed	observe	VERB
bjp-23039	212	20	.	.	PUNCT
bjp-23039	213	1	(	(	PUNCT
bjp-23039	213	2	b	b	X
bjp-23039	213	3	)	)	PUNCT
bjp-23039	213	4	relative	relative	ADJ
bjp-23039	213	5	expressions	expression	NOUN
bjp-23039	213	6	of	of	ADP
bjp-23039	213	7	the	the	DET
bjp-23039	213	8	map	map	NOUN
bjp-23039	213	9	kinases	kinase	NOUN
bjp-23039	213	10	.	.	PUNCT
bjp-23039	214	1	values	value	NOUN
bjp-23039	214	2	are	be	AUX
bjp-23039	214	3	represented	represent	VERB
bjp-23039	214	4	as	as	ADP
bjp-23039	214	5	mean	mean	NOUN
bjp-23039	214	6	±	±	NUM
bjp-23039	214	7	sd	sd	NOUN
bjp-23039	214	8	;	;	PUNCT
bjp-23039	214	9	n=3	n=3	NUM
bjp-23039	214	10	;	;	PUNCT
bjp-23039	214	11	*	*	PUNCT
bjp-23039	214	12	represents	represent	VERB
bjp-23039	214	13	p<0.05	p<0.05	NOUN
bjp-23039	214	14	compared	compare	VERB
bjp-23039	214	15	with	with	ADP
bjp-23039	214	16	control	control	NOUN
bjp-23039	214	17	as	as	SCONJ
bjp-23039	214	18	determined	determine	VERB
bjp-23039	214	19	by	by	ADP
bjp-23039	214	20	one	one	NUM
bjp-23039	214	21	-	-	PUNCT
bjp-23039	214	22	way	way	NOUN
bjp-23039	214	23	anova	anova	PROPN
bjp-23039	214	24	jnk	jnk	PROPN
bjp-23039	214	25	p	p	PROPN
bjp-23039	214	26	-	-	PUNCT
bjp-23039	214	27	jnk	jnk	PROPN
bjp-23039	214	28	erk1/2	erk1/2	PROPN
bjp-23039	214	29	p	p	PROPN
bjp-23039	214	30	-	-	PUNCT
bjp-23039	214	31	erk1/2	erk1/2	PROPN
bjp-23039	214	32	p38	p38	NOUN
bjp-23039	214	33	p	p	NOUN
bjp-23039	214	34	-	-	PUNCT
bjp-23039	214	35	p38	p38	NOUN
bjp-23039	214	36	c	c	PROPN
bjp-23039	214	37	-	-	PUNCT
bjp-23039	214	38	jun	jun	PROPN
bjp-23039	214	39	p	p	PROPN
bjp-23039	214	40	-	-	PUNCT
bjp-23039	214	41	c	c	NOUN
bjp-23039	214	42	-	-	PUNCT
bjp-23039	214	43	jun	jun	PROPN
bjp-23039	214	44	β	β	NOUN
bjp-23039	214	45	-	-	NOUN
bjp-23039	214	46	actin	actin	NOUN
bjp-23039	214	47	µm	µm	X
bjp-23039	214	48	fisetin	fisetin	VERB
bjp-23039	214	49	0	0	NUM
bjp-23039	214	50	20	20	NUM
bjp-23039	214	51	40	40	NUM
bjp-23039	214	52	60	60	NUM
bjp-23039	214	53	80	80	NUM
bjp-23039	214	54	100	100	NUM
bjp-23039	214	55	b	b	NOUN
bjp-23039	214	56	r	r	NOUN
bjp-23039	214	57	el	el	PROPN
bjp-23039	214	58	at	at	ADP
bjp-23039	214	59	iv	iv	NUM
bjp-23039	214	60	e	e	X
bjp-23039	214	61	ex	ex	X
bjp-23039	214	62	pr	pr	VERB
bjp-23039	214	63	es	es	X
bjp-23039	214	64	si	si	X
bjp-23039	214	65	on	on	ADP
bjp-23039	214	66	(	(	PUNCT
bjp-23039	214	67	%	%	INTJ
bjp-23039	214	68	o	o	X
bjp-23039	214	69	f	f	X
bjp-23039	214	70	c	c	NOUN
bjp-23039	214	71	on	on	ADP
bjp-23039	214	72	tro	tro	X
bjp-23039	214	73	l	l	NOUN
bjp-23039	214	74	)	)	PUNCT
bjp-23039	214	75	200	200	NUM
bjp-23039	214	76	150	150	NUM
bjp-23039	214	77	100	100	NUM
bjp-23039	214	78	50	50	NUM
bjp-23039	214	79	0	0	NUM
bjp-23039	214	80	control	control	NOUN
bjp-23039	214	81	20	20	NUM
bjp-23039	214	82	µm	µm	NOUN
bjp-23039	214	83	fisetin	fisetin	VERB
bjp-23039	214	84	40	40	NUM
bjp-23039	214	85	µm	µm	NOUN
bjp-23039	214	86	fisetin	fisetin	VERB
bjp-23039	214	87	60	60	NUM
bjp-23039	214	88	µm	µm	NOUN
bjp-23039	214	89	fisetin	fisetin	VERB
bjp-23039	214	90	80	80	NUM
bjp-23039	214	91	µm	µm	NOUN
bjp-23039	214	92	fisetin	fisetin	VERB
bjp-23039	214	93	100	100	NUM
bjp-23039	214	94	µm	µm	NOUN
bjp-23039	214	95	fisetin	fisetin	VERB
bjp-23039	214	96	jnk	jnk	PROPN
bjp-23039	214	97	p	p	PROPN
bjp-23039	214	98	-	-	PUNCT
bjp-23039	214	99	jnk	jnk	PROPN
bjp-23039	214	100	erk1/2	erk1/2	PROPN
bjp-23039	214	101	p	p	PROPN
bjp-23039	214	102	-	-	PUNCT
bjp-23039	214	103	erk1/2	erk1/2	PROPN
bjp-23039	214	104	p38	p38	NOUN
bjp-23039	214	105	p	p	NOUN
bjp-23039	214	106	-	-	PUNCT
bjp-23039	214	107	p38	p38	NOUN
bjp-23039	214	108	c	c	PROPN
bjp-23039	214	109	-	-	PUNCT
bjp-23039	214	110	jun	jun	PROPN
bjp-23039	214	111	*	*	PUNCT
bjp-23039	215	1	*	*	PUNCT
bjp-23039	216	1	*	*	PUNCT
bjp-23039	217	1	*	*	PUNCT
bjp-23039	218	1	*	*	PUNCT
bjp-23039	218	2	*	*	PUNCT
bjp-23039	218	3	*	*	PUNCT
bjp-23039	218	4	p	p	X
bjp-23039	218	5	-	-	PUNCT
bjp-23039	218	6	c	c	NOUN
bjp-23039	218	7	-	-	PUNCT
bjp-23039	218	8	jun	jun	PROPN
bjp-23039	218	9	*	*	PUNCT
bjp-23039	219	1	*	*	PUNCT
bjp-23039	220	1	*	*	PUNCT
bjp-23039	221	1	*	*	PUNCT
bjp-23039	222	1	*	*	PUNCT
bjp-23039	223	1	*	*	PUNCT
bjp-23039	224	1	*	*	PUNCT
bjp-23039	225	1	*	*	PUNCT
bjp-23039	226	1	*	*	PUNCT
bjp-23039	227	1	*	*	PUNCT
bjp-23039	228	1	*	*	PUNCT
bjp-23039	229	1	*	*	PUNCT
bjp-23039	230	1	*	*	PUNCT
bjp-23039	231	1	*	*	PUNCT
bjp-23039	232	1	*	*	PUNCT
bjp-23039	233	1	*	*	PUNCT
bjp-23039	234	1	*	*	PUNCT
bjp-23039	235	1	*	*	PUNCT
bjp-23039	236	1	*	*	PUNCT
bjp-23039	237	1	*	*	PUNCT
bjp-23039	238	1	*	*	PUNCT
bjp-23039	239	1	*	*	PUNCT
bjp-23039	240	1	*	*	PUNCT
bjp-23039	241	1	*	*	PUNCT
bjp-23039	242	1	*	*	PUNCT
bjp-23039	243	1	*	*	PUNCT
bjp-23039	244	1	*	*	PUNCT
bjp-23039	245	1	*	*	PUNCT
bjp-23039	246	1	*	*	PUNCT
bjp-23039	246	2	*	*	PUNCT
bjp-23039	246	3	*	*	PUNCT
bjp-23039	246	4	826	826	NUM
bjp-23039	246	5	bangladesh	bangladesh	PROPN
bjp-23039	246	6	j	j	PROPN
bjp-23039	246	7	pharmacol	pharmacol	PROPN
bjp-23039	246	8	2015	2015	NUM
bjp-23039	246	9	;	;	PUNCT
bjp-23039	246	10	10	10	NUM
bjp-23039	246	11	:	:	SYM
bjp-23039	246	12	820	820	NUM
bjp-23039	246	13	-	-	SYM
bjp-23039	246	14	829	829	NUM
bjp-23039	246	15	has	have	AUX
bjp-23039	246	16	been	be	AUX
bjp-23039	246	17	highly	highly	ADV
bjp-23039	246	18	expressed	express	VERB
bjp-23039	246	19	in	in	ADP
bjp-23039	246	20	some	some	DET
bjp-23039	246	21	hematopoietic	hematopoietic	ADJ
bjp-23039	246	22	and	and	CCONJ
bjp-23039	246	23	solid	solid	ADJ
bjp-23039	246	24	tumors	tumor	NOUN
bjp-23039	246	25	(	(	PUNCT
bjp-23039	246	26	white	white	PROPN
bjp-23039	246	27	et	et	PROPN
bjp-23039	246	28	al	al	PROPN
bjp-23039	246	29	.	.	PROPN
bjp-23039	246	30	,	,	PUNCT
bjp-23039	246	31	2005	2005	NUM
bjp-23039	246	32	)	)	PUNCT
bjp-23039	246	33	.	.	PUNCT
bjp-23039	247	1	down	down	ADP
bjp-23039	247	2	-	-	PUNCT
bjp-23039	247	3	regulation	regulation	NOUN
bjp-23039	247	4	of	of	ADP
bjp-23039	247	5	bcl	bcl	PROPN
bjp-23039	247	6	-	-	PROPN
bjp-23039	247	7	xl	xl	PROPN
bjp-23039	247	8	and	and	CCONJ
bjp-23039	247	9	bcl-2	bcl-2	NOUN
bjp-23039	247	10	observed	observe	VERB
bjp-23039	247	11	in	in	ADP
bjp-23039	247	12	fisetin	fisetin	ADJ
bjp-23039	247	13	exposure	exposure	NOUN
bjp-23039	247	14	could	could	AUX
bjp-23039	247	15	have	have	AUX
bjp-23039	247	16	contributed	contribute	VERB
bjp-23039	247	17	to	to	ADP
bjp-23039	247	18	disruption	disruption	NOUN
bjp-23039	247	19	of	of	ADP
bjp-23039	247	20	the	the	DET
bjp-23039	247	21	membrane	membrane	NOUN
bjp-23039	247	22	integrity	integrity	NOUN
bjp-23039	247	23	leading	lead	VERB
bjp-23039	247	24	to	to	ADP
bjp-23039	247	25	intrinsic	intrinsic	ADJ
bjp-23039	247	26	apoptosis	apoptosis	NOUN
bjp-23039	247	27	(	(	PUNCT
bjp-23039	247	28	gottlieb	gottlieb	PROPN
bjp-23039	247	29	et	et	PROPN
bjp-23039	247	30	al	al	PROPN
bjp-23039	247	31	.	.	PROPN
bjp-23039	247	32	,	,	PUNCT
bjp-23039	247	33	2000	2000	NUM
bjp-23039	247	34	)	)	PUNCT
bjp-23039	247	35	.	.	PUNCT
bjp-23039	248	1	down	down	ADP
bjp-23039	248	2	-	-	PUNCT
bjp-23039	248	3	regulation	regulation	NOUN
bjp-23039	248	4	of	of	ADP
bjp-23039	248	5	bcl	bcl	PROPN
bjp-23039	248	6	-	-	PROPN
bjp-23039	248	7	xl	xl	PROPN
bjp-23039	248	8	was	be	AUX
bjp-23039	248	9	accompanied	accompany	VERB
bjp-23039	248	10	with	with	ADP
bjp-23039	248	11	a	a	DET
bjp-23039	248	12	marked	mark	VERB
bjp-23039	248	13	up	up	ADP
bjp-23039	248	14	-	-	PUNCT
bjp-23039	248	15	regulation	regulation	NOUN
bjp-23039	248	16	in	in	ADP
bjp-23039	248	17	the	the	DET
bjp-23039	248	18	expression	expression	NOUN
bjp-23039	248	19	of	of	ADP
bjp-23039	248	20	the	the	DET
bjp-23039	248	21	pro	pro	ADJ
bjp-23039	248	22	-	-	ADJ
bjp-23039	248	23	apoptotic	apoptotic	ADJ
bjp-23039	248	24	proteins	protein	NOUN
bjp-23039	248	25	bax	bax	NOUN
bjp-23039	248	26	and	and	CCONJ
bjp-23039	248	27	bad	bad	ADJ
bjp-23039	248	28	,	,	PUNCT
bjp-23039	248	29	suggesting	suggest	VERB
bjp-23039	248	30	that	that	SCONJ
bjp-23039	248	31	fisetin	fisetin	NOUN
bjp-23039	248	32	modulates	modulate	VERB
bjp-23039	248	33	the	the	DET
bjp-23039	248	34	expressions	expression	NOUN
bjp-23039	248	35	of	of	ADP
bjp-23039	248	36	not	not	PART
bjp-23039	248	37	only	only	ADV
bjp-23039	248	38	caspases	caspase	NOUN
bjp-23039	248	39	but	but	CCONJ
bjp-23039	248	40	also	also	ADV
bjp-23039	248	41	the	the	DET
bjp-23039	248	42	apoptotic	apoptotic	ADJ
bjp-23039	248	43	proteins	protein	NOUN
bjp-23039	248	44	to	to	ADP
bjp-23039	248	45	trigger	trigger	NOUN
bjp-23039	248	46	apoptosis	apoptosis	NOUN
bjp-23039	248	47	in	in	ADP
bjp-23039	248	48	the	the	DET
bjp-23039	248	49	osteosarcoma	osteosarcoma	ADJ
bjp-23039	248	50	cells	cell	NOUN
bjp-23039	248	51	.	.	PUNCT
bjp-23039	249	1	mapk	mapk	NOUN
bjp-23039	249	2	signalling	signal	VERB
bjp-23039	249	3	cascades	cascade	NOUN
bjp-23039	249	4	are	be	AUX
bjp-23039	249	5	important	important	ADJ
bjp-23039	249	6	regulators	regulator	NOUN
bjp-23039	249	7	of	of	ADP
bjp-23039	249	8	stress	stress	NOUN
bjp-23039	249	9	responses	response	NOUN
bjp-23039	249	10	,	,	PUNCT
bjp-23039	249	11	including	include	VERB
bjp-23039	249	12	the	the	DET
bjp-23039	249	13	induction	induction	NOUN
bjp-23039	249	14	of	of	ADP
bjp-23039	249	15	apoptosis	apoptosis	NOUN
bjp-23039	249	16	(	(	PUNCT
bjp-23039	249	17	johnson	johnson	PROPN
bjp-23039	249	18	and	and	CCONJ
bjp-23039	249	19	lapadat	lapadat	PROPN
bjp-23039	249	20	,	,	PUNCT
bjp-23039	249	21	2002	2002	NUM
bjp-23039	249	22	;	;	PUNCT
bjp-23039	249	23	park	park	NOUN
bjp-23039	249	24	,	,	PUNCT
bjp-23039	249	25	2011	2011	NUM
bjp-23039	249	26	;	;	PUNCT
bjp-23039	249	27	you	you	PRON
bjp-23039	249	28	and	and	CCONJ
bjp-23039	249	29	park	park	NOUN
bjp-23039	249	30	,	,	PUNCT
bjp-23039	249	31	2011	2011	NUM
bjp-23039	249	32	)	)	PUNCT
bjp-23039	249	33	.	.	PUNCT
bjp-23039	250	1	previous	previous	ADJ
bjp-23039	250	2	studies	study	NOUN
bjp-23039	250	3	have	have	AUX
bjp-23039	250	4	suggested	suggest	VERB
bjp-23039	250	5	that	that	SCONJ
bjp-23039	250	6	jnk	jnk	PROPN
bjp-23039	250	7	,	,	PUNCT
bjp-23039	250	8	p38	p38	NOUN
bjp-23039	250	9	,	,	PUNCT
bjp-23039	250	10	and	and	CCONJ
bjp-23039	250	11	erk1/2	erk1/2	NUM
bjp-23039	250	12	pathways	pathway	NOUN
bjp-23039	250	13	have	have	VERB
bjp-23039	250	14	critical	critical	ADJ
bjp-23039	250	15	roles	role	NOUN
bjp-23039	250	16	in	in	ADP
bjp-23039	250	17	the	the	DET
bjp-23039	250	18	induction	induction	NOUN
bjp-23039	250	19	of	of	ADP
bjp-23039	250	20	apoptosis	apoptosis	NOUN
bjp-23039	250	21	(	(	PUNCT
bjp-23039	250	22	tournier	tournier	NOUN
bjp-23039	250	23	et	et	PROPN
bjp-23039	250	24	al	al	PROPN
bjp-23039	250	25	.	.	PROPN
bjp-23039	250	26	,	,	PUNCT
bjp-23039	250	27	2000	2000	NUM
bjp-23039	250	28	;	;	PUNCT
bjp-23039	250	29	kim	kim	PROPN
bjp-23039	250	30	and	and	CCONJ
bjp-23039	250	31	chung	chung	PROPN
bjp-23039	250	32	,	,	PUNCT
bjp-23039	250	33	2008	2008	NUM
bjp-23039	250	34	)	)	PUNCT
bjp-23039	250	35	.	.	PUNCT
bjp-23039	251	1	activation	activation	NOUN
bjp-23039	251	2	of	of	ADP
bjp-23039	251	3	erk	erk	PROPN
bjp-23039	251	4	has	have	AUX
bjp-23039	251	5	been	be	AUX
bjp-23039	251	6	shown	show	VERB
bjp-23039	251	7	to	to	PART
bjp-23039	251	8	promote	promote	VERB
bjp-23039	251	9	proliferation	proliferation	NOUN
bjp-23039	251	10	and	and	CCONJ
bjp-23039	251	11	survival	survival	NOUN
bjp-23039	251	12	of	of	ADP
bjp-23039	251	13	most	most	ADJ
bjp-23039	251	14	of	of	ADP
bjp-23039	251	15	the	the	DET
bjp-23039	251	16	cell	cell	NOUN
bjp-23039	251	17	types	type	NOUN
bjp-23039	251	18	(	(	PUNCT
bjp-23039	251	19	lewis	lewis	PROPN
bjp-23039	251	20	et	et	PROPN
bjp-23039	251	21	al	al	PROPN
bjp-23039	251	22	.	.	PROPN
bjp-23039	251	23	,	,	PUNCT
bjp-23039	251	24	1998	1998	NUM
bjp-23039	251	25	;	;	PUNCT
bjp-23039	251	26	wang	wang	PROPN
bjp-23039	251	27	et	et	PROPN
bjp-23039	251	28	al	al	PROPN
bjp-23039	251	29	.	.	PROPN
bjp-23039	251	30	,	,	PUNCT
bjp-23039	251	31	1998	1998	NUM
bjp-23039	251	32	)	)	PUNCT
bjp-23039	251	33	and	and	CCONJ
bjp-23039	251	34	as	as	ADV
bjp-23039	251	35	well	well	ADV
bjp-23039	251	36	regulate	regulate	VERB
bjp-23039	251	37	cell	cell	NOUN
bjp-23039	251	38	apoptosis	apoptosis	NOUN
bjp-23039	251	39	(	(	PUNCT
bjp-23039	251	40	ishikawa	ishikawa	PROPN
bjp-23039	251	41	and	and	CCONJ
bjp-23039	251	42	kitamura	kitamura	PROPN
bjp-23039	251	43	,	,	PUNCT
bjp-23039	251	44	1999	1999	NUM
bjp-23039	251	45	)	)	PUNCT
bjp-23039	251	46	.	.	PUNCT
bjp-23039	252	1	nevertheless	nevertheless	ADV
bjp-23039	252	2	,	,	PUNCT
bjp-23039	252	3	the	the	DET
bjp-23039	252	4	map	map	NOUN
bjp-23039	252	5	kinasesjnk	kinasesjnk	ADJ
bjp-23039	252	6	and	and	CCONJ
bjp-23039	252	7	p38	p38	NOUN
bjp-23039	252	8	are	be	AUX
bjp-23039	252	9	often	often	ADV
bjp-23039	252	10	activated	activate	VERB
bjp-23039	252	11	by	by	ADP
bjp-23039	252	12	oxidative	oxidative	ADJ
bjp-23039	252	13	stress	stress	NOUN
bjp-23039	252	14	and	and	CCONJ
bjp-23039	252	15	xenobiotics	xenobiotic	NOUN
bjp-23039	252	16	,	,	PUNCT
bjp-23039	252	17	and	and	CCONJ
bjp-23039	252	18	have	have	AUX
bjp-23039	252	19	been	be	AUX
bjp-23039	252	20	reported	report	VERB
bjp-23039	252	21	to	to	PART
bjp-23039	252	22	subsequently	subsequently	ADV
bjp-23039	252	23	induce	induce	VERB
bjp-23039	252	24	apoptosis	apoptosis	NOUN
bjp-23039	252	25	(	(	PUNCT
bjp-23039	252	26	lewis	lewis	PROPN
bjp-23039	252	27	et	et	PROPN
bjp-23039	252	28	al	al	PROPN
bjp-23039	252	29	.	.	PROPN
bjp-23039	252	30	,	,	PUNCT
bjp-23039	252	31	1998	1998	NUM
bjp-23039	252	32	;	;	PUNCT
bjp-23039	252	33	obata	obata	VERB
bjp-23039	252	34	et	et	PROPN
bjp-23039	252	35	al	al	PROPN
bjp-23039	252	36	.	.	PROPN
bjp-23039	252	37	,	,	PUNCT
bjp-23039	252	38	2000	2000	NUM
bjp-23039	252	39	)	)	PUNCT
bjp-23039	252	40	.	.	PUNCT
bjp-23039	253	1	studies	study	NOUN
bjp-23039	253	2	suggest	suggest	VERB
bjp-23039	253	3	that	that	SCONJ
bjp-23039	253	4	p38	p38	NOUN
bjp-23039	253	5	and/or	and/or	CCONJ
bjp-23039	253	6	jnk	jnk	PROPN
bjp-23039	253	7	directly	directly	ADV
bjp-23039	253	8	activate	activate	VERB
bjp-23039	253	9	the	the	DET
bjp-23039	253	10	caspase	caspase	NOUN
bjp-23039	253	11	cascade	cascade	NOUN
bjp-23039	253	12	,	,	PUNCT
bjp-23039	253	13	and	and	CCONJ
bjp-23039	253	14	also	also	ADV
bjp-23039	253	15	cause	cause	VERB
bjp-23039	253	16	the	the	DET
bjp-23039	253	17	activation	activation	NOUN
bjp-23039	253	18	of	of	ADP
bjp-23039	253	19	the	the	DET
bjp-23039	253	20	apoptotic	apoptotic	ADJ
bjp-23039	253	21	transcription	transcription	NOUN
bjp-23039	253	22	factor	factor	NOUN
bjp-23039	253	23	c	c	NOUN
bjp-23039	253	24	-	-	PUNCT
bjp-23039	253	25	jun	jun	PROPN
bjp-23039	253	26	(	(	PUNCT
bjp-23039	253	27	davis	davis	PROPN
bjp-23039	253	28	,	,	PUNCT
bjp-23039	253	29	2000	2000	NUM
bjp-23039	253	30	)	)	PUNCT
bjp-23039	253	31	.	.	PUNCT
bjp-23039	254	1	in	in	ADP
bjp-23039	254	2	our	our	PRON
bjp-23039	254	3	study	study	NOUN
bjp-23039	254	4	,	,	PUNCT
bjp-23039	254	5	fisetin	fisetin	NOUN
bjp-23039	254	6	brought	bring	VERB
bjp-23039	254	7	about	about	ADP
bjp-23039	254	8	marked	mark	VERB
bjp-23039	254	9	down	down	ADP
bjp-23039	254	10	-	-	PUNCT
bjp-23039	254	11	regulation	regulation	NOUN
bjp-23039	254	12	of	of	ADP
bjp-23039	254	13	the	the	DET
bjp-23039	254	14	phosphorylated	phosphorylate	VERB
bjp-23039	254	15	forms	form	NOUN
bjp-23039	254	16	of	of	ADP
bjp-23039	254	17	erk1/2	erk1/2	PROPN
bjp-23039	254	18	,	,	PUNCT
bjp-23039	254	19	whereas	whereas	SCONJ
bjp-23039	254	20	up	up	ADV
bjp-23039	254	21	-	-	PUNCT
bjp-23039	254	22	regulated	regulate	VERB
bjp-23039	254	23	the	the	DET
bjp-23039	254	24	phosphorylated	phosphorylate	VERB
bjp-23039	254	25	levels	level	NOUN
bjp-23039	254	26	of	of	ADP
bjp-23039	254	27	jnk	jnk	PROPN
bjp-23039	254	28	,	,	PUNCT
bjp-23039	254	29	and	and	CCONJ
bjp-23039	254	30	p	p	X
bjp-23039	254	31	-	-	NOUN
bjp-23039	254	32	p38	p38	NOUN
bjp-23039	254	33	in	in	ADP
bjp-23039	254	34	a	a	DET
bjp-23039	254	35	dose	dose	NOUN
bjp-23039	254	36	-	-	PUNCT
bjp-23039	254	37	dependent	dependent	ADJ
bjp-23039	254	38	manner	manner	NOUN
bjp-23039	254	39	.	.	PUNCT
bjp-23039	255	1	this	this	DET
bjp-23039	255	2	observed	observed	ADJ
bjp-23039	255	3	activation	activation	NOUN
bjp-23039	255	4	of	of	ADP
bjp-23039	255	5	jnk	jnk	PROPN
bjp-23039	255	6	could	could	AUX
bjp-23039	255	7	have	have	AUX
bjp-23039	255	8	caused	cause	VERB
bjp-23039	255	9	up	up	ADP
bjp-23039	255	10	-	-	PUNCT
bjp-23039	255	11	regulation	regulation	NOUN
bjp-23039	255	12	of	of	ADP
bjp-23039	255	13	p	p	NOUN
bjp-23039	255	14	-	-	PUNCT
bjp-23039	255	15	c	c	NOUN
bjp-23039	255	16	-	-	PUNCT
bjp-23039	255	17	jun	jun	PROPN
bjp-23039	255	18	in	in	ADP
bjp-23039	255	19	the	the	DET
bjp-23039	255	20	u-2	u-2	PROPN
bjp-23039	255	21	os	os	PROPN
bjp-23039	255	22	cells	cell	NOUN
bjp-23039	255	23	.	.	PUNCT
bjp-23039	256	1	excessive	excessive	ADJ
bjp-23039	256	2	generation	generation	NOUN
bjp-23039	256	3	of	of	ADP
bjp-23039	256	4	ros	ros	PROPN
bjp-23039	256	5	could	could	AUX
bjp-23039	256	6	interfere	interfere	VERB
bjp-23039	256	7	with	with	ADP
bjp-23039	256	8	cellular	cellular	ADJ
bjp-23039	256	9	signalling	signal	VERB
bjp-23039	256	10	pathways	pathway	NOUN
bjp-23039	256	11	(	(	PUNCT
bjp-23039	256	12	simon	simon	PROPN
bjp-23039	256	13	et	et	PROPN
bjp-23039	256	14	al	al	PROPN
bjp-23039	256	15	.	.	PROPN
bjp-23039	256	16	,	,	PUNCT
bjp-23039	256	17	2000	2000	NUM
bjp-23039	256	18	;	;	PUNCT
bjp-23039	256	19	trachootham	trachootham	NOUN
bjp-23039	256	20	et	et	PROPN
bjp-23039	256	21	al	al	PROPN
bjp-23039	256	22	.	.	PROPN
bjp-23039	256	23	,	,	PUNCT
bjp-23039	256	24	2009	2009	NUM
bjp-23039	256	25	)	)	PUNCT
bjp-23039	256	26	and	and	CCONJ
bjp-23039	256	27	is	be	AUX
bjp-23039	256	28	one	one	NUM
bjp-23039	256	29	of	of	ADP
bjp-23039	256	30	the	the	DET
bjp-23039	256	31	contributing	contribute	VERB
bjp-23039	256	32	factors	factor	NOUN
bjp-23039	256	33	in	in	ADP
bjp-23039	256	34	the	the	DET
bjp-23039	256	35	malignant	malignant	ADJ
bjp-23039	256	36	transformation	transformation	NOUN
bjp-23039	256	37	of	of	ADP
bjp-23039	256	38	normal	normal	ADJ
bjp-23039	256	39	cells	cell	NOUN
bjp-23039	256	40	via	via	ADP
bjp-23039	256	41	inducing	induce	VERB
bjp-23039	256	42	oxidative	oxidative	ADJ
bjp-23039	256	43	dna	dna	NOUN
bjp-23039	256	44	damage	damage	NOUN
bjp-23039	256	45	(	(	PUNCT
bjp-23039	256	46	klaunig	klaunig	PROPN
bjp-23039	256	47	et	et	PROPN
bjp-23039	256	48	al	al	PROPN
bjp-23039	256	49	.	.	PROPN
bjp-23039	256	50	,	,	PUNCT
bjp-23039	256	51	2010	2010	NUM
bjp-23039	256	52	;	;	PUNCT
bjp-23039	256	53	lee	lee	PROPN
bjp-23039	256	54	et	et	PROPN
bjp-23039	256	55	al	al	PROPN
bjp-23039	256	56	.	.	PROPN
bjp-23039	256	57	,	,	PUNCT
bjp-23039	256	58	2012	2012	NUM
bjp-23039	256	59	)	)	PUNCT
bjp-23039	256	60	.	.	PUNCT
bjp-23039	257	1	however	however	ADV
bjp-23039	257	2	,	,	PUNCT
bjp-23039	257	3	induction	induction	NOUN
bjp-23039	257	4	of	of	ADP
bjp-23039	257	5	ros	ros	PROPN
bjp-23039	257	6	plays	play	VERB
bjp-23039	257	7	a	a	DET
bjp-23039	257	8	significant	significant	ADJ
bjp-23039	257	9	role	role	NOUN
bjp-23039	257	10	in	in	ADP
bjp-23039	257	11	the	the	DET
bjp-23039	257	12	chemotherapeutic	chemotherapeutic	ADJ
bjp-23039	257	13	activity	activity	NOUN
bjp-23039	257	14	of	of	ADP
bjp-23039	257	15	several	several	ADJ
bjp-23039	257	16	anticancer	anticancer	NOUN
bjp-23039	257	17	drugs	drug	NOUN
bjp-23039	257	18	and	and	CCONJ
bjp-23039	257	19	anticancer	anticancer	NOUN
bjp-23039	257	20	compounds	compound	NOUN
bjp-23039	257	21	(	(	PUNCT
bjp-23039	257	22	fruehauf	fruehauf	PROPN
bjp-23039	257	23	and	and	CCONJ
bjp-23039	257	24	meyskens	meysken	NOUN
bjp-23039	257	25	,	,	PUNCT
bjp-23039	257	26	2007	2007	NUM
bjp-23039	257	27	;	;	PUNCT
bjp-23039	257	28	trachootham	trachootham	NOUN
bjp-23039	257	29	et	et	PROPN
bjp-23039	257	30	al	al	PROPN
bjp-23039	257	31	.	.	PROPN
bjp-23039	257	32	,	,	PUNCT
bjp-23039	257	33	2009	2009	NUM
bjp-23039	257	34	)	)	PUNCT
bjp-23039	257	35	.	.	PUNCT
bjp-23039	258	1	drug	drug	NOUN
bjp-23039	258	2	-	-	PUNCT
bjp-23039	258	3	induced	induce	VERB
bjp-23039	258	4	ros	ros	PROPN
bjp-23039	258	5	mediates	mediate	VERB
bjp-23039	258	6	the	the	DET
bjp-23039	258	7	activation	activation	NOUN
bjp-23039	258	8	of	of	ADP
bjp-23039	258	9	map	map	NOUN
bjp-23039	258	10	kinases	kinase	NOUN
bjp-23039	258	11	,	,	PUNCT
bjp-23039	258	12	disrupts	disrupt	VERB
bjp-23039	258	13	the	the	DET
bjp-23039	258	14	mitochondrial	mitochondrial	ADJ
bjp-23039	258	15	membrane	membrane	NOUN
bjp-23039	258	16	potential	potential	NOUN
bjp-23039	258	17	and	and	CCONJ
bjp-23039	258	18	subsequently	subsequently	ADV
bjp-23039	258	19	activates	activate	VERB
bjp-23039	258	20	apoptotic	apoptotic	ADJ
bjp-23039	258	21	caspases	caspase	NOUN
bjp-23039	258	22	in	in	ADP
bjp-23039	258	23	cancer	cancer	NOUN
bjp-23039	258	24	cells	cell	NOUN
bjp-23039	258	25	(	(	PUNCT
bjp-23039	258	26	zhang	zhang	X
bjp-23039	258	27	et	et	PROPN
bjp-23039	258	28	al	al	PROPN
bjp-23039	258	29	.	.	PROPN
bjp-23039	258	30	,	,	PUNCT
bjp-23039	258	31	2000	2000	NUM
bjp-23039	258	32	;	;	PUNCT
bjp-23039	259	1	raza	raza	PROPN
bjp-23039	259	2	et	et	PROPN
bjp-23039	259	3	al	al	PROPN
bjp-23039	259	4	.	.	PROPN
bjp-23039	259	5	,	,	PUNCT
bjp-23039	259	6	2011	2011	NUM
bjp-23039	259	7	)	)	PUNCT
bjp-23039	259	8	.	.	PUNCT
bjp-23039	260	1	jnk	jnk	PROPN
bjp-23039	260	2	could	could	AUX
bjp-23039	260	3	be	be	AUX
bjp-23039	260	4	activated	activate	VERB
bjp-23039	260	5	by	by	ADP
bjp-23039	260	6	stimuli	stimulus	NOUN
bjp-23039	260	7	as	as	ADP
bjp-23039	260	8	cytokines	cytokine	NOUN
bjp-23039	260	9	,	,	PUNCT
bjp-23039	260	10	ros	ros	PROPN
bjp-23039	260	11	,	,	PUNCT
bjp-23039	260	12	pathogens	pathogen	NOUN
bjp-23039	260	13	,	,	PUNCT
bjp-23039	260	14	toxins	toxin	NOUN
bjp-23039	260	15	,	,	PUNCT
bjp-23039	260	16	drugs	drug	NOUN
bjp-23039	260	17	,	,	PUNCT
bjp-23039	260	18	and	and	CCONJ
bjp-23039	260	19	metabolic	metabolic	NOUN
bjp-23039	260	20	changes	change	NOUN
bjp-23039	260	21	(	(	PUNCT
bjp-23039	260	22	seki	seki	PROPN
bjp-23039	260	23	et	et	PROPN
bjp-23039	260	24	al	al	PROPN
bjp-23039	260	25	.	.	PROPN
bjp-23039	260	26	,	,	PUNCT
bjp-23039	260	27	2012	2012	NUM
bjp-23039	260	28	)	)	PUNCT
bjp-23039	260	29	.	.	PUNCT
bjp-23039	261	1	thus	thus	ADV
bjp-23039	261	2	the	the	DET
bjp-23039	261	3	observed	observe	VERB
bjp-23039	261	4	raised	raise	VERB
bjp-23039	261	5	levels	level	NOUN
bjp-23039	261	6	of	of	ADP
bjp-23039	261	7	ros	ros	PROPN
bjp-23039	261	8	could	could	AUX
bjp-23039	261	9	have	have	AUX
bjp-23039	261	10	also	also	ADV
bjp-23039	261	11	contributed	contribute	VERB
bjp-23039	261	12	to	to	ADP
bjp-23039	261	13	the	the	DET
bjp-23039	261	14	activation	activation	NOUN
bjp-23039	261	15	of	of	ADP
bjp-23039	261	16	jnk	jnk	PROPN
bjp-23039	261	17	leading	lead	VERB
bjp-23039	261	18	to	to	ADP
bjp-23039	261	19	apoptosis	apoptosis	NOUN
bjp-23039	261	20	.	.	PUNCT
bjp-23039	262	1	fisetin	fisetin	NOUN
bjp-23039	262	2	thus	thus	ADV
bjp-23039	262	3	could	could	AUX
bjp-23039	262	4	have	have	AUX
bjp-23039	262	5	promoted	promote	VERB
bjp-23039	262	6	the	the	DET
bjp-23039	262	7	generation	generation	NOUN
bjp-23039	262	8	of	of	ADP
bjp-23039	262	9	ros	ros	PROPN
bjp-23039	262	10	and	and	CCONJ
bjp-23039	262	11	caused	cause	VERB
bjp-23039	262	12	the	the	DET
bjp-23039	262	13	activation	activation	NOUN
bjp-23039	262	14	of	of	ADP
bjp-23039	262	15	jnk	jnk	PROPN
bjp-23039	262	16	via	via	ADP
bjp-23039	262	17	ros	ros	PROPN
bjp-23039	262	18	-	-	PUNCT
bjp-23039	262	19	induction	induction	NOUN
bjp-23039	262	20	or	or	CCONJ
bjp-23039	262	21	could	could	AUX
bjp-23039	262	22	have	have	AUX
bjp-23039	262	23	acted	act	VERB
bjp-23039	262	24	directly	directly	ADV
bjp-23039	262	25	.	.	PUNCT
bjp-23039	263	1	pi3k	pi3k	NOUN
bjp-23039	263	2	/	/	SYM
bjp-23039	263	3	akt	akt	PROPN
bjp-23039	263	4	pathway	pathway	NOUN
bjp-23039	263	5	is	be	AUX
bjp-23039	263	6	another	another	DET
bjp-23039	263	7	major	major	ADJ
bjp-23039	263	8	signalling	signal	VERB
bjp-23039	263	9	cascade	cascade	NOUN
bjp-23039	263	10	that	that	PRON
bjp-23039	263	11	is	be	AUX
bjp-23039	263	12	deregulated	deregulate	VERB
bjp-23039	263	13	in	in	ADP
bjp-23039	263	14	many	many	ADJ
bjp-23039	263	15	cancers	cancer	NOUN
bjp-23039	263	16	(	(	PUNCT
bjp-23039	263	17	porta	porta	NOUN
bjp-23039	263	18	et	et	PROPN
bjp-23039	263	19	al	al	PROPN
bjp-23039	263	20	.	.	PROPN
bjp-23039	263	21	,	,	PUNCT
bjp-23039	263	22	2014	2014	NUM
bjp-23039	263	23	)	)	PUNCT
bjp-23039	263	24	.	.	PUNCT
bjp-23039	264	1	dysregulation	dysregulation	NOUN
bjp-23039	264	2	of	of	ADP
bjp-23039	264	3	this	this	DET
bjp-23039	264	4	pathway	pathway	NOUN
bjp-23039	264	5	plays	play	VERB
bjp-23039	264	6	a	a	DET
bjp-23039	264	7	vital	vital	ADJ
bjp-23039	264	8	role	role	NOUN
bjp-23039	264	9	in	in	ADP
bjp-23039	264	10	multiple	multiple	ADJ
bjp-23039	264	11	pathological	pathological	ADJ
bjp-23039	264	12	processes	process	NOUN
bjp-23039	264	13	of	of	ADP
bjp-23039	264	14	os	os	NOUN
bjp-23039	264	15	including	include	VERB
bjp-23039	264	16	cell	cell	NOUN
bjp-23039	264	17	cycle	cycle	NOUN
bjp-23039	264	18	progression	progression	NOUN
bjp-23039	264	19	,	,	PUNCT
bjp-23039	264	20	tumorigenesis	tumorigenesis	NOUN
bjp-23039	264	21	,	,	PUNCT
bjp-23039	264	22	invasion	invasion	NOUN
bjp-23039	264	23	,	,	PUNCT
bjp-23039	264	24	angiogenesis	angiogenesis	NOUN
bjp-23039	264	25	,	,	PUNCT
bjp-23039	264	26	metastasis	metastasis	NOUN
bjp-23039	264	27	,	,	PUNCT
bjp-23039	264	28	apoptosis	apoptosis	NOUN
bjp-23039	264	29	and	and	CCONJ
bjp-23039	264	30	chemoresistance	chemoresistance	NOUN
bjp-23039	264	31	(	(	PUNCT
bjp-23039	264	32	zhang	zhang	X
bjp-23039	264	33	et	et	PROPN
bjp-23039	264	34	al	al	PROPN
bjp-23039	264	35	.	.	PROPN
bjp-23039	264	36	,	,	PUNCT
bjp-23039	264	37	2015	2015	NUM
bjp-23039	264	38	)	)	PUNCT
bjp-23039	264	39	.	.	PUNCT
bjp-23039	265	1	activation	activation	NOUN
bjp-23039	265	2	of	of	ADP
bjp-23039	265	3	pi3k	pi3k	PROPN
bjp-23039	265	4	leads	lead	VERB
bjp-23039	265	5	to	to	ADP
bjp-23039	265	6	the	the	DET
bjp-23039	265	7	activation	activation	NOUN
bjp-23039	265	8	of	of	ADP
bjp-23039	265	9	major	major	ADJ
bjp-23039	265	10	effector	effector	NOUN
bjp-23039	265	11	akt	akt	PROPN
bjp-23039	265	12	through	through	ADP
bjp-23039	265	13	phosphorylation	phosphorylation	NOUN
bjp-23039	265	14	.	.	PUNCT
bjp-23039	266	1	activated	activate	VERB
bjp-23039	266	2	akt	akt	PROPN
bjp-23039	266	3	translocates	translocate	NOUN
bjp-23039	266	4	to	to	ADP
bjp-23039	266	5	the	the	DET
bjp-23039	266	6	cytoplasm	cytoplasm	NOUN
bjp-23039	266	7	and	and	CCONJ
bjp-23039	266	8	nucleus	nucleus	NOUN
bjp-23039	266	9	and	and	CCONJ
bjp-23039	266	10	further	further	ADJ
bjp-23039	266	11	cause	cause	VERB
bjp-23039	266	12	phosphorylation	phosphorylation	NOUN
bjp-23039	266	13	of	of	ADP
bjp-23039	266	14	many	many	ADJ
bjp-23039	266	15	downstream	downstream	ADJ
bjp-23039	266	16	effector	effector	NOUN
bjp-23039	266	17	proteins	protein	NOUN
bjp-23039	266	18	that	that	PRON
bjp-23039	266	19	regulate	regulate	VERB
bjp-23039	266	20	various	various	ADJ
bjp-23039	266	21	cellular	cellular	ADJ
bjp-23039	266	22	functions	function	NOUN
bjp-23039	266	23	such	such	ADJ
bjp-23039	266	24	as	as	ADP
bjp-23039	266	25	mtor	mtor	NOUN
bjp-23039	266	26	and	and	CCONJ
bjp-23039	266	27	gsk3β	gsk3β	PROPN
bjp-23039	266	28	,	,	PUNCT
bjp-23039	266	29	which	which	PRON
bjp-23039	266	30	further	far	ADV
bjp-23039	266	31	leads	lead	VERB
bjp-23039	266	32	to	to	ADP
bjp-23039	266	33	cell	cell	NOUN
bjp-23039	266	34	cycle	cycle	NOUN
bjp-23039	266	35	progression	progression	NOUN
bjp-23039	266	36	.	.	PUNCT
bjp-23039	267	1	additionally	additionally	ADV
bjp-23039	267	2	,	,	PUNCT
bjp-23039	267	3	akt	akt	PROPN
bjp-23039	267	4	increases	increase	VERB
bjp-23039	267	5	the	the	DET
bjp-23039	267	6	activity	activity	NOUN
bjp-23039	267	7	of	of	ADP
bjp-23039	267	8	inhibitor	inhibitor	NOUN
bjp-23039	267	9	of	of	ADP
bjp-23039	267	10	κb	κb	PROPN
bjp-23039	267	11	(	(	PUNCT
bjp-23039	267	12	iκb	iκb	PROPN
bjp-23039	267	13	)	)	PUNCT
bjp-23039	267	14	kinase	kinase	PROPN
bjp-23039	267	15	(	(	PUNCT
bjp-23039	267	16	ikk	ikk	PROPN
bjp-23039	267	17	)	)	PUNCT
bjp-23039	267	18	,	,	PUNCT
bjp-23039	267	19	that	that	PRON
bjp-23039	267	20	leads	lead	VERB
bjp-23039	267	21	to	to	ADP
bjp-23039	267	22	phosphorylation	phosphorylation	NOUN
bjp-23039	267	23	and	and	CCONJ
bjp-23039	267	24	thus	thus	ADV
bjp-23039	267	25	degradation	degradation	NOUN
bjp-23039	267	26	of	of	ADP
bjp-23039	267	27	iκb	iκb	NOUN
bjp-23039	267	28	causing	cause	VERB
bjp-23039	267	29	the	the	DET
bjp-23039	267	30	subsequent	subsequent	ADJ
bjp-23039	267	31	release	release	NOUN
bjp-23039	267	32	of	of	ADP
bjp-23039	267	33	nf	nf	NOUN
bjp-23039	267	34	-	-	PUNCT
bjp-23039	267	35	κb	κb	NOUN
bjp-23039	267	36	,	,	PUNCT
bjp-23039	267	37	a	a	DET
bjp-23039	267	38	central	central	ADJ
bjp-23039	267	39	signalling	signal	VERB
bjp-23039	267	40	factor	factor	NOUN
bjp-23039	267	41	that	that	PRON
bjp-23039	267	42	has	have	AUX
bjp-23039	267	43	been	be	AUX
bjp-23039	267	44	reported	report	VERB
bjp-23039	267	45	to	to	PART
bjp-23039	267	46	be	be	AUX
bjp-23039	267	47	involved	involve	VERB
bjp-23039	267	48	in	in	ADP
bjp-23039	267	49	tumorigenesis	tumorigenesis	NOUN
bjp-23039	267	50	of	of	ADP
bjp-23039	267	51	various	various	ADJ
bjp-23039	267	52	cancers	cancer	NOUN
bjp-23039	267	53	(	(	PUNCT
bjp-23039	267	54	ahmad	ahmad	PROPN
bjp-23039	267	55	et	et	PROPN
bjp-23039	267	56	al	al	PROPN
bjp-23039	267	57	.	.	PROPN
bjp-23039	267	58	,	,	PUNCT
bjp-23039	267	59	2013	2013	NUM
bjp-23039	267	60	)	)	PUNCT
bjp-23039	267	61	.	.	PUNCT
bjp-23039	268	1	fisetin	fisetin	NOUN
bjp-23039	268	2	at	at	ADP
bjp-23039	268	3	various	various	ADJ
bjp-23039	268	4	concentrations	concentration	NOUN
bjp-23039	268	5	caused	cause	VERB
bjp-23039	268	6	down	down	ADP
bjp-23039	268	7	-	-	PUNCT
bjp-23039	268	8	regulation	regulation	NOUN
bjp-23039	268	9	of	of	ADP
bjp-23039	268	10	p	p	NOUN
bjp-23039	268	11	-	-	PUNCT
bjp-23039	268	12	akt	akt	NOUN
bjp-23039	268	13	in	in	ADP
bjp-23039	268	14	a	a	DET
bjp-23039	268	15	dose	dose	NOUN
bjp-23039	268	16	-	-	PUNCT
bjp-23039	268	17	dependent	dependent	ADJ
bjp-23039	268	18	way	way	NOUN
bjp-23039	268	19	.	.	PUNCT
bjp-23039	269	1	this	this	DET
bjp-23039	269	2	decrease	decrease	NOUN
bjp-23039	269	3	in	in	ADP
bjp-23039	269	4	the	the	DET
bjp-23039	269	5	activation	activation	NOUN
bjp-23039	269	6	of	of	ADP
bjp-23039	269	7	p	p	PROPN
bjp-23039	269	8	-	-	PUNCT
bjp-23039	269	9	akt	akt	PROPN
bjp-23039	269	10	could	could	AUX
bjp-23039	269	11	have	have	AUX
bjp-23039	269	12	contributed	contribute	VERB
bjp-23039	269	13	the	the	DET
bjp-23039	269	14	reduced	reduce	VERB
bjp-23039	269	15	expression	expression	NOUN
bjp-23039	269	16	levels	level	NOUN
bjp-23039	269	17	of	of	ADP
bjp-23039	269	18	p	p	PROPN
bjp-23039	269	19	-	-	PUNCT
bjp-23039	269	20	gsk3β	gsk3β	PROPN
bjp-23039	269	21	that	that	PRON
bjp-23039	269	22	further	far	ADV
bjp-23039	269	23	inhibited	inhibit	VERB
bjp-23039	269	24	cyclin	cyclin	NOUN
bjp-23039	269	25	d1	d1	PROPN
bjp-23039	269	26	expression	expression	NOUN
bjp-23039	269	27	.	.	PUNCT
bjp-23039	270	1	moreover	moreover	ADV
bjp-23039	270	2	,	,	PUNCT
bjp-23039	270	3	fisetin	fisetin	ADJ
bjp-23039	270	4	effectively	effectively	ADV
bjp-23039	270	5	inhibited	inhibit	VERB
bjp-23039	270	6	nf	nf	ADJ
bjp-23039	270	7	-	-	PUNCT
bjp-23039	270	8	κb	κb	NOUN
bjp-23039	270	9	and	and	CCONJ
bjp-23039	270	10	as	as	ADV
bjp-23039	270	11	well	well	ADV
bjp-23039	270	12	modulated	modulate	VERB
bjp-23039	270	13	the	the	DET
bjp-23039	270	14	levels	level	NOUN
bjp-23039	270	15	of	of	ADP
bjp-23039	270	16	iκb	iκb	NOUN
bjp-23039	270	17	and	and	CCONJ
bjp-23039	270	18	mtorc1	mtorc1	NOUN
bjp-23039	270	19	.	.	PUNCT
bjp-23039	271	1	pten	pten	PROPN
bjp-23039	271	2	levels	level	NOUN
bjp-23039	271	3	were	be	AUX
bjp-23039	271	4	enhanced	enhance	VERB
bjp-23039	271	5	significantly	significantly	ADV
bjp-23039	271	6	by	by	ADP
bjp-23039	271	7	fisetin	fisetin	PROPN
bjp-23039	271	8	.	.	PUNCT
bjp-23039	272	1	pten	pten	PROPN
bjp-23039	272	2	is	be	AUX
bjp-23039	272	3	a	a	DET
bjp-23039	272	4	main	main	ADJ
bjp-23039	272	5	negative	negative	ADJ
bjp-23039	272	6	regulator	regulator	NOUN
bjp-23039	272	7	of	of	ADP
bjp-23039	272	8	the	the	DET
bjp-23039	272	9	pi3k	pi3k	PROPN
bjp-23039	272	10	/	/	SYM
bjp-23039	272	11	akt	akt	PROPN
bjp-23039	272	12	pathway	pathway	NOUN
bjp-23039	272	13	,	,	PUNCT
bjp-23039	272	14	and	and	CCONJ
bjp-23039	272	15	loss	loss	NOUN
bjp-23039	272	16	of	of	ADP
bjp-23039	272	17	pten	pten	ADJ
bjp-23039	272	18	activity	activity	NOUN
bjp-23039	272	19	has	have	AUX
bjp-23039	272	20	been	be	AUX
bjp-23039	272	21	frequently	frequently	ADV
bjp-23039	272	22	observed	observe	VERB
bjp-23039	272	23	in	in	ADP
bjp-23039	272	24	os	os	PROPN
bjp-23039	272	25	(	(	PUNCT
bjp-23039	272	26	nielsen	nielsen	PROPN
bjp-23039	272	27	-	-	PUNCT
bjp-23039	272	28	preiss	preiss	PROPN
bjp-23039	272	29	et	et	PROPN
bjp-23039	272	30	al	al	PROPN
bjp-23039	272	31	.	.	PROPN
bjp-23039	272	32	,	,	PUNCT
bjp-23039	272	33	2003	2003	NUM
bjp-23039	272	34	)	)	PUNCT
bjp-23039	272	35	.	.	PUNCT
bjp-23039	273	1	thus	thus	ADV
bjp-23039	273	2	,	,	PUNCT
bjp-23039	273	3	pten	pten	VERB
bjp-23039	273	4	activators	activator	NOUN
bjp-23039	273	5	may	may	AUX
bjp-23039	273	6	be	be	AUX
bjp-23039	273	7	an	an	DET
bjp-23039	273	8	alternative	alternative	ADJ
bjp-23039	273	9	approach	approach	NOUN
bjp-23039	273	10	for	for	ADP
bjp-23039	273	11	suppression	suppression	NOUN
bjp-23039	273	12	of	of	ADP
bjp-23039	273	13	the	the	DET
bjp-23039	273	14	pathway	pathway	NOUN
bjp-23039	273	15	in	in	ADP
bjp-23039	273	16	os	os	PROPN
bjp-23039	273	17	.	.	PROPN
bjp-23039	273	18	fisetin	fisetin	PROPN
bjp-23039	273	19	induced	induce	VERB
bjp-23039	273	20	pten	pten	NOUN
bjp-23039	273	21	levels	level	NOUN
bjp-23039	273	22	contribute	contribute	VERB
bjp-23039	273	23	to	to	ADP
bjp-23039	273	24	the	the	DET
bjp-23039	273	25	negative	negative	ADJ
bjp-23039	273	26	regulation	regulation	NOUN
bjp-23039	273	27	of	of	ADP
bjp-23039	273	28	the	the	DET
bjp-23039	273	29	pi3k	pi3k	PROPN
bjp-23039	273	30	/	/	SYM
bjp-23039	273	31	akt	akt	PROPN
bjp-23039	273	32	pathway	pathway	NOUN
bjp-23039	273	33	thus	thus	ADV
bjp-23039	273	34	reducing	reduce	VERB
bjp-23039	273	35	cell	cell	NOUN
bjp-23039	273	36	cycle	cycle	NOUN
bjp-23039	273	37	progression	progression	NOUN
bjp-23039	273	38	and	and	CCONJ
bjp-23039	273	39	promoting	promote	VERB
bjp-23039	273	40	apoptosis	apoptosis	NOUN
bjp-23039	273	41	.	.	PUNCT
bjp-23039	274	1	conclusion	conclusion	NOUN
bjp-23039	274	2	fisetin	fisetin	VERB
bjp-23039	274	3	at	at	ADP
bjp-23039	274	4	20	20	NUM
bjp-23039	274	5	-	-	SYM
bjp-23039	274	6	100	100	NUM
bjp-23039	274	7	µm	µm	ADP
bjp-23039	274	8	concentration	concentration	NOUN
bjp-23039	274	9	potentially	potentially	ADV
bjp-23039	274	10	induced	induce	VERB
bjp-23039	274	11	apoptosis	apoptosis	NOUN
bjp-23039	274	12	of	of	ADP
bjp-23039	274	13	the	the	DET
bjp-23039	274	14	u-2	u-2	PROPN
bjp-23039	274	15	os	os	PROPN
bjp-23039	274	16	cells	cell	NOUN
bjp-23039	274	17	by	by	ADP
bjp-23039	274	18	up	up	ADV
bjp-23039	274	19	-	-	PUNCT
bjp-23039	274	20	regulating	regulate	VERB
bjp-23039	274	21	the	the	DET
bjp-23039	274	22	apoptotic	apoptotic	ADJ
bjp-23039	274	23	proteins	protein	NOUN
bjp-23039	274	24	and	and	CCONJ
bjp-23039	274	25	also	also	ADV
bjp-23039	274	26	modulating	modulate	VERB
bjp-23039	274	27	the	the	DET
bjp-23039	274	28	expression	expression	NOUN
bjp-23039	274	29	of	of	ADP
bjp-23039	274	30	mapk	mapk	NOUN
bjp-23039	274	31	and	and	CCONJ
bjp-23039	274	32	pi3k	pi3k	PROPN
bjp-23039	274	33	/	/	SYM
bjp-23039	274	34	akt	akt	PROPN
bjp-23039	274	35	signalling	signal	VERB
bjp-23039	274	36	cascades	cascade	NOUN
bjp-23039	274	37	proteins	protein	NOUN
bjp-23039	274	38	.	.	PUNCT
bjp-23039	275	1	references	reference	NOUN
bjp-23039	275	2	ahmad	ahmad	VERB
bjp-23039	275	3	a	a	PRON
bjp-23039	275	4	,	,	PUNCT
bjp-23039	275	5	biersack	biersack	PROPN
bjp-23039	275	6	b	b	PROPN
bjp-23039	275	7	,	,	PUNCT
bjp-23039	275	8	li	li	PROPN
bjp-23039	275	9	y	y	PROPN
bjp-23039	275	10	,	,	PUNCT
bjp-23039	275	11	kong	kong	PROPN
bjp-23039	275	12	d	d	PROPN
bjp-23039	275	13	,	,	PUNCT
bjp-23039	275	14	bao	bao	PROPN
bjp-23039	275	15	b	b	NUM
bjp-23039	275	16	,	,	PUNCT
bjp-23039	275	17	schobert	schobert	NOUN
bjp-23039	275	18	r	r	NOUN
bjp-23039	275	19	,	,	PUNCT
bjp-23039	275	20	padhye	padhye	NOUN
bjp-23039	275	21	sb	sb	PROPN
bjp-23039	275	22	,	,	PUNCT
bjp-23039	275	23	sarkar	sarkar	PROPN
bjp-23039	275	24	fh	fh	PROPN
bjp-23039	275	25	.	.	PROPN
bjp-23039	275	26	targeted	target	VERB
bjp-23039	275	27	regulation	regulation	NOUN
bjp-23039	275	28	of	of	ADP
bjp-23039	275	29	pi3k	pi3k	PROPN
bjp-23039	275	30	/	/	SYM
bjp-23039	275	31	akt	akt	PROPN
bjp-23039	275	32	/	/	SYM
bjp-23039	275	33	mtor	mtor	PROPN
bjp-23039	275	34	/	/	SYM
bjp-23039	275	35	nf	nf	PROPN
bjp-23039	275	36	-kappab	-kappab	NOUN
bjp-23039	275	37	signaling	signal	VERB
bjp-23039	275	38	by	by	ADP
bjp-23039	275	39	indole	indole	ADJ
bjp-23039	275	40	compounds	compound	NOUN
bjp-23039	275	41	and	and	CCONJ
bjp-23039	275	42	their	their	PRON
bjp-23039	275	43	derivatives	derivative	NOUN
bjp-23039	275	44	:	:	PUNCT
bjp-23039	275	45	mechanistic	mechanistic	ADJ
bjp-23039	275	46	details	detail	NOUN
bjp-23039	275	47	and	and	CCONJ
bjp-23039	275	48	biological	biological	ADJ
bjp-23039	275	49	implications	implication	NOUN
bjp-23039	275	50	for	for	ADP
bjp-23039	275	51	cancer	cancer	NOUN
bjp-23039	275	52	therapy	therapy	NOUN
bjp-23039	275	53	.	.	PUNCT
bjp-23039	276	1	anticancer	anticancer	NOUN
bjp-23039	276	2	agents	agent	NOUN
bjp-23039	276	3	med	med	PROPN
bjp-23039	276	4	chem	chem	NOUN
bjp-23039	276	5	.	.	PUNCT
bjp-23039	277	1	2013	2013	NUM
bjp-23039	277	2	;	;	PUNCT
bjp-23039	277	3	13	13	NUM
bjp-23039	277	4	:	:	SYM
bjp-23039	277	5	1002	1002	NUM
bjp-23039	277	6	-	-	SYM
bjp-23039	277	7	13	13	NUM
bjp-23039	277	8	.	.	PUNCT
bjp-23039	278	1	anilkumar	anilkumar	PROPN
bjp-23039	278	2	u	u	PROPN
bjp-23039	278	3	,	,	PUNCT
bjp-23039	278	4	prehn	prehn	VERB
bjp-23039	278	5	jh	jh	PROPN
bjp-23039	278	6	.	.	PUNCT
bjp-23039	279	1	anti	anti	ADJ
bjp-23039	279	2	-	-	ADJ
bjp-23039	279	3	apoptotic	apoptotic	ADJ
bjp-23039	279	4	bcl-2	bcl-2	ADJ
bjp-23039	279	5	family	family	NOUN
bjp-23039	279	6	proteins	protein	NOUN
bjp-23039	279	7	in	in	ADP
bjp-23039	279	8	acute	acute	ADJ
bjp-23039	279	9	neural	neural	ADJ
bjp-23039	279	10	injury	injury	NOUN
bjp-23039	279	11	.	.	PUNCT
bjp-23039	280	1	front	front	ADJ
bjp-23039	280	2	cell	cell	NOUN
bjp-23039	280	3	neurosci	neurosci	NOUN
bjp-23039	280	4	.	.	PUNCT
bjp-23039	281	1	2014	2014	NUM
bjp-23039	281	2	;	;	PUNCT
bjp-23039	281	3	8	8	NUM
bjp-23039	281	4	:	:	SYM
bjp-23039	281	5	281	281	NUM
bjp-23039	281	6	.	.	PUNCT
bjp-23039	282	1	avisetti	avisetti	PROPN
bjp-23039	282	2	dr	dr	PROPN
bjp-23039	282	3	,	,	PUNCT
bjp-23039	282	4	babu	babu	PROPN
bjp-23039	282	5	ks	ks	PROPN
bjp-23039	282	6	,	,	PUNCT
bjp-23039	282	7	kalivendi	kalivendi	PROPN
bjp-23039	282	8	sv	sv	PROPN
bjp-23039	282	9	.	.	PROPN
bjp-23039	282	10	activation	activation	NOUN
bjp-23039	282	11	of	of	ADP
bjp-23039	282	12	p38	p38	NOUN
bjp-23039	282	13	/	/	SYM
bjp-23039	282	14	jnk	jnk	PROPN
bjp-23039	282	15	pathway	pathway	NOUN
bjp-23039	282	16	is	be	AUX
bjp-23039	282	17	responsible	responsible	ADJ
bjp-23039	282	18	for	for	ADP
bjp-23039	282	19	embelin	embelin	NOUN
bjp-23039	282	20	induced	induce	VERB
bjp-23039	282	21	apoptosis	apoptosis	NOUN
bjp-23039	282	22	in	in	ADP
bjp-23039	282	23	lung	lung	NOUN
bjp-23039	282	24	cancer	cancer	NOUN
bjp-23039	282	25	cells	cell	NOUN
bjp-23039	282	26	:	:	PUNCT
bjp-23039	282	27	transitional	transitional	ADJ
bjp-23039	282	28	role	role	NOUN
bjp-23039	282	29	of	of	ADP
bjp-23039	282	30	reactive	reactive	ADJ
bjp-23039	282	31	oxygen	oxygen	NOUN
bjp-23039	282	32	species	specie	NOUN
bjp-23039	282	33	.	.	PUNCT
bjp-23039	283	1	plos	plos	PROPN
bjp-23039	283	2	one	one	NUM
bjp-23039	283	3	2014	2014	NUM
bjp-23039	283	4	;	;	PUNCT
bjp-23039	283	5	9	9	NUM
bjp-23039	283	6	:	:	PUNCT
bjp-23039	284	1	e87050	e87050	PROPN
bjp-23039	284	2	chen	chen	PROPN
bjp-23039	285	1	yc	yc	PROPN
bjp-23039	285	2	,	,	PUNCT
bjp-23039	285	3	shen	shen	PROPN
bjp-23039	285	4	sc	sc	PROPN
bjp-23039	285	5	,	,	PUNCT
bjp-23039	285	6	lee	lee	PROPN
bjp-23039	285	7	wr	wr	PROPN
bjp-23039	285	8	,	,	PUNCT
bjp-23039	285	9	lin	lin	PROPN
bjp-23039	285	10	hy	hy	PROPN
bjp-23039	285	11	,	,	PUNCT
bjp-23039	285	12	ko	ko	PROPN
bjp-23039	285	13	ch	ch	PROPN
bjp-23039	285	14	,	,	PUNCT
bjp-23039	285	15	shih	shih	PROPN
bjp-23039	285	16	cm	cm	PROPN
bjp-23039	285	17	,	,	PUNCT
bjp-23039	285	18	yang	yang	PROPN
bjp-23039	285	19	ll	ll	PROPN
bjp-23039	285	20	.	.	PUNCT
bjp-23039	285	21	wogonin	wogonin	VERB
bjp-23039	285	22	and	and	CCONJ
bjp-23039	285	23	fisetin	fisetin	VERB
bjp-23039	285	24	induction	induction	NOUN
bjp-23039	285	25	of	of	ADP
bjp-23039	285	26	apoptosis	apoptosis	NOUN
bjp-23039	285	27	through	through	ADP
bjp-23039	285	28	activation	activation	NOUN
bjp-23039	285	29	of	of	ADP
bjp-23039	285	30	caspase	caspase	PROPN
bjp-23039	285	31	3	3	NUM
bjp-23039	285	32	cascade	cascade	NOUN
bjp-23039	285	33	and	and	CCONJ
bjp-23039	285	34	alternative	alternative	ADJ
bjp-23039	285	35	expression	expression	NOUN
bjp-23039	285	36	of	of	ADP
bjp-23039	285	37	p21	p21	NOUN
bjp-23039	285	38	protein	protein	NOUN
bjp-23039	285	39	in	in	ADP
bjp-23039	285	40	hepatocellular	hepatocellular	ADJ
bjp-23039	285	41	carcinoma	carcinoma	NOUN
bjp-23039	285	42	cells	cell	NOUN
bjp-23039	285	43	sk	sk	ADP
bjp-23039	285	44	-	-	PUNCT
bjp-23039	285	45	hep-1	hep-1	NOUN
bjp-23039	285	46	.	.	NOUN
bjp-23039	286	1	bangladesh	bangladesh	PROPN
bjp-23039	286	2	j	j	PROPN
bjp-23039	286	3	pharmacol	pharmacol	PROPN
bjp-23039	286	4	2015	2015	NUM
bjp-23039	286	5	;	;	PUNCT
bjp-23039	286	6	10	10	NUM
bjp-23039	286	7	:	:	SYM
bjp-23039	286	8	820	820	NUM
bjp-23039	286	9	-	-	SYM
bjp-23039	286	10	829	829	NUM
bjp-23039	286	11	827	827	NUM
bjp-23039	286	12	arch	arch	ADJ
bjp-23039	286	13	toxicol	toxicol	NOUN
bjp-23039	286	14	.	.	PUNCT
bjp-23039	286	15	2002	2002	NUM
bjp-23039	286	16	;	;	PUNCT
bjp-23039	286	17	76	76	NUM
bjp-23039	286	18	:	:	SYM
bjp-23039	286	19	351	351	NUM
bjp-23039	286	20	-	-	SYM
bjp-23039	286	21	59	59	NUM
bjp-23039	286	22	.	.	PUNCT
bjp-23039	287	1	chen	chen	PROPN
bjp-23039	287	2	y	y	PROPN
bjp-23039	287	3	,	,	PUNCT
bjp-23039	287	4	mcmillan	mcmillan	NOUN
bjp-23039	287	5	-	-	PUNCT
bjp-23039	287	6	ward	ward	NOUN
bjp-23039	287	7	e	e	NOUN
bjp-23039	287	8	,	,	PUNCT
bjp-23039	287	9	kong	kong	PROPN
bjp-23039	287	10	j	j	PROPN
bjp-23039	287	11	,	,	PUNCT
bjp-23039	287	12	israels	israels	PROPN
bjp-23039	287	13	sj	sj	PROPN
bjp-23039	287	14	,	,	PUNCT
bjp-23039	287	15	gibson	gibson	PROPN
bjp-23039	287	16	sb	sb	PROPN
bjp-23039	287	17	.	.	PROPN
bjp-23039	287	18	mitochondrial	mitochondrial	ADJ
bjp-23039	287	19	electron	electron	NOUN
bjp-23039	287	20	-	-	PUNCT
bjp-23039	287	21	transport	transport	NOUN
bjp-23039	287	22	chain	chain	NOUN
bjp-23039	287	23	inhibitors	inhibitor	NOUN
bjp-23039	287	24	of	of	ADP
bjp-23039	287	25	complexes	complex	NOUN
bjp-23039	287	26	i	i	PRON
bjp-23039	287	27	and	and	CCONJ
bjp-23039	287	28	ii	ii	PROPN
bjp-23039	287	29	induce	induce	VERB
bjp-23039	287	30	autophagic	autophagic	ADJ
bjp-23039	287	31	cell	cell	NOUN
bjp-23039	287	32	death	death	NOUN
bjp-23039	287	33	mediated	mediate	VERB
bjp-23039	287	34	by	by	ADP
bjp-23039	287	35	reactive	reactive	ADJ
bjp-23039	287	36	oxygen	oxygen	NOUN
bjp-23039	287	37	species	specie	NOUN
bjp-23039	287	38	.	.	PUNCT
bjp-23039	288	1	j	j	PROPN
bjp-23039	288	2	cell	cell	PROPN
bjp-23039	288	3	sci	sci	PROPN
bjp-23039	288	4	.	.	PROPN
bjp-23039	288	5	2007	2007	NUM
bjp-23039	288	6	;	;	PUNCT
bjp-23039	288	7	120	120	NUM
bjp-23039	288	8	:	:	SYM
bjp-23039	288	9	4155	4155	NUM
bjp-23039	288	10	-	-	SYM
bjp-23039	288	11	66	66	NUM
bjp-23039	288	12	.	.	PUNCT
bjp-23039	289	1	chen	chen	PROPN
bjp-23039	289	2	yc	yc	PROPN
bjp-23039	289	3	,	,	PUNCT
bjp-23039	289	4	chang	chang	PROPN
bjp-23039	289	5	cn	cn	PROPN
bjp-23039	289	6	,	,	PUNCT
bjp-23039	289	7	hsu	hsu	PROPN
bjp-23039	289	8	hc	hc	PROPN
bjp-23039	289	9	,	,	PUNCT
bjp-23039	289	10	chiou	chiou	NOUN
bjp-23039	289	11	sj	sj	PROPN
bjp-23039	289	12	,	,	PUNCT
bjp-23039	289	13	lee	lee	PROPN
bjp-23039	289	14	lt	lt	PROPN
bjp-23039	289	15	,	,	PUNCT
bjp-23039	289	16	hseu	hseu	PROPN
bjp-23039	289	17	th	th	PROPN
bjp-23039	289	18	.	.	PUNCT
bjp-23039	289	19	sennoside	sennoside	PROPN
bjp-23039	289	20	b	b	PROPN
bjp-23039	289	21	inhibits	inhibit	VERB
bjp-23039	289	22	pdgf	pdgf	ADJ
bjp-23039	289	23	receptor	receptor	NOUN
bjp-23039	289	24	signaling	signal	VERB
bjp-23039	289	25	and	and	CCONJ
bjp-23039	289	26	cell	cell	NOUN
bjp-23039	289	27	proliferation	proliferation	NOUN
bjp-23039	289	28	induced	induce	VERB
bjp-23039	289	29	by	by	ADP
bjp-23039	289	30	pdgf	pdgf	NOUN
bjp-23039	289	31	-	-	PUNCT
bjp-23039	289	32	bb	bb	NOUN
bjp-23039	289	33	in	in	ADP
bjp-23039	289	34	human	human	ADJ
bjp-23039	289	35	osteosarcoma	osteosarcoma	ADJ
bjp-23039	289	36	cells	cell	NOUN
bjp-23039	289	37	.	.	PUNCT
bjp-23039	290	1	life	life	PROPN
bjp-23039	290	2	sci	sci	PROPN
bjp-23039	290	3	.	.	PROPN
bjp-23039	290	4	2009	2009	NUM
bjp-23039	290	5	;	;	PUNCT
bjp-23039	290	6	84	84	NUM
bjp-23039	290	7	:	:	PUNCT
bjp-23039	290	8	915	915	NUM
bjp-23039	290	9	-	-	SYM
bjp-23039	290	10	22	22	NUM
bjp-23039	290	11	.	.	PUNCT
bjp-23039	291	1	chou	chou	PROPN
bjp-23039	291	2	aj	aj	PROPN
bjp-23039	291	3	,	,	PUNCT
bjp-23039	291	4	gorlick	gorlick	PROPN
bjp-23039	291	5	r.	r.	PROPN
bjp-23039	291	6	chemotherapy	chemotherapy	PROPN
bjp-23039	291	7	resistance	resistance	NOUN
bjp-23039	291	8	in	in	ADP
bjp-23039	291	9	osteosarcoma	osteosarcoma	NOUN
bjp-23039	291	10	:	:	PUNCT
bjp-23039	291	11	current	current	ADJ
bjp-23039	291	12	challenges	challenge	NOUN
bjp-23039	291	13	and	and	CCONJ
bjp-23039	291	14	future	future	ADJ
bjp-23039	291	15	directions	direction	NOUN
bjp-23039	291	16	.	.	PUNCT
bjp-23039	292	1	expert	expert	NOUN
bjp-23039	292	2	rev	rev	PROPN
bjp-23039	292	3	anticancer	anticancer	NOUN
bjp-23039	292	4	ther	ther	ADV
bjp-23039	292	5	.	.	PUNCT
bjp-23039	293	1	2006	2006	NUM
bjp-23039	293	2	;	;	PUNCT
bjp-23039	293	3	6	6	NUM
bjp-23039	293	4	:	:	SYM
bjp-23039	293	5	1075	1075	NUM
bjp-23039	293	6	-	-	SYM
bjp-23039	293	7	85	85	NUM
bjp-23039	293	8	.	.	PUNCT
bjp-23039	294	1	chou	chou	PROPN
bjp-23039	294	2	rh	rh	PROPN
bjp-23039	294	3	,	,	PUNCT
bjp-23039	294	4	hsieh	hsieh	PROPN
bjp-23039	294	5	sc	sc	PROPN
bjp-23039	294	6	,	,	PUNCT
bjp-23039	294	7	yu	yu	PROPN
bjp-23039	294	8	yl	yl	PROPN
bjp-23039	294	9	,	,	PUNCT
bjp-23039	294	10	huang	huang	PROPN
bjp-23039	294	11	mh	mh	PROPN
bjp-23039	294	12	,	,	PUNCT
bjp-23039	294	13	huang	huang	PROPN
bjp-23039	294	14	yc	yc	PROPN
bjp-23039	294	15	,	,	PUNCT
bjp-23039	294	16	hsieh	hsieh	PROPN
bjp-23039	294	17	yh	yh	PROPN
bjp-23039	294	18	.	.	PROPN
bjp-23039	294	19	fisetin	fisetin	PROPN
bjp-23039	294	20	inhibits	inhibit	VERB
bjp-23039	294	21	migration	migration	NOUN
bjp-23039	294	22	and	and	CCONJ
bjp-23039	294	23	invasion	invasion	NOUN
bjp-23039	294	24	of	of	ADP
bjp-23039	294	25	human	human	ADJ
bjp-23039	294	26	cervical	cervical	ADJ
bjp-23039	294	27	cancer	cancer	NOUN
bjp-23039	294	28	cells	cell	NOUN
bjp-23039	294	29	by	by	ADP
bjp-23039	294	30	down	down	ADV
bjp-23039	294	31	-	-	PUNCT
bjp-23039	294	32	regulating	regulate	VERB
bjp-23039	294	33	urokinase	urokinase	NOUN
bjp-23039	294	34	plasminogen	plasminogen	NOUN
bjp-23039	294	35	activator	activator	NOUN
bjp-23039	294	36	expression	expression	NOUN
bjp-23039	294	37	through	through	ADP
bjp-23039	294	38	suppressing	suppress	VERB
bjp-23039	294	39	the	the	DET
bjp-23039	294	40	p38	p38	NOUN
bjp-23039	294	41	mapk	mapk	NOUN
bjp-23039	294	42	-	-	PUNCT
bjp-23039	294	43	dependent	dependent	ADJ
bjp-23039	294	44	nf	nf	ADJ
bjp-23039	294	45	-	-	PUNCT
bjp-23039	294	46	κb	κb	NOUN
bjp-23039	294	47	signaling	signal	VERB
bjp-23039	294	48	pathway	pathway	NOUN
bjp-23039	294	49	.	.	PUNCT
bjp-23039	295	1	plos	plos	PROPN
bjp-23039	295	2	one	one	NUM
bjp-23039	295	3	2013	2013	NUM
bjp-23039	295	4	;	;	PUNCT
bjp-23039	295	5	8	8	NUM
bjp-23039	295	6	:	:	PUNCT
bjp-23039	295	7	e71983	e71983	PROPN
bjp-23039	295	8	.	.	PUNCT
bjp-23039	296	1	davis	davis	PROPN
bjp-23039	296	2	rj	rj	PROPN
bjp-23039	296	3	.	.	PROPN
bjp-23039	296	4	signal	signal	PROPN
bjp-23039	296	5	transduction	transduction	NOUN
bjp-23039	296	6	by	by	ADP
bjp-23039	296	7	the	the	DET
bjp-23039	296	8	jnk	jnk	PROPN
bjp-23039	296	9	group	group	NOUN
bjp-23039	296	10	of	of	ADP
bjp-23039	296	11	map	map	NOUN
bjp-23039	296	12	kinases	kinase	NOUN
bjp-23039	296	13	.	.	PUNCT
bjp-23039	297	1	cell	cell	NOUN
bjp-23039	297	2	2000	2000	NUM
bjp-23039	297	3	;	;	PUNCT
bjp-23039	297	4	103	103	NUM
bjp-23039	297	5	:	:	SYM
bjp-23039	297	6	239	239	NUM
bjp-23039	297	7	-	-	SYM
bjp-23039	297	8	52	52	NUM
bjp-23039	297	9	.	.	PUNCT
bjp-23039	298	1	fruehauf	fruehauf	PROPN
bjp-23039	298	2	jp	jp	PROPN
bjp-23039	298	3	,	,	PUNCT
bjp-23039	298	4	meyskens	meyskens	PROPN
bjp-23039	298	5	fl	fl	PROPN
bjp-23039	298	6	jr	jr	PROPN
bjp-23039	298	7	.	.	PROPN
bjp-23039	298	8	reactive	reactive	ADJ
bjp-23039	298	9	oxygen	oxygen	NOUN
bjp-23039	298	10	species	specie	NOUN
bjp-23039	298	11	:	:	PUNCT
bjp-23039	298	12	a	a	DET
bjp-23039	298	13	breath	breath	NOUN
bjp-23039	298	14	of	of	ADP
bjp-23039	298	15	life	life	NOUN
bjp-23039	298	16	or	or	CCONJ
bjp-23039	298	17	death	death	NOUN
bjp-23039	298	18	?	?	PUNCT
bjp-23039	299	1	clin	clin	PROPN
bjp-23039	299	2	cancer	cancer	NOUN
bjp-23039	299	3	res	re	NOUN
bjp-23039	299	4	.	.	PUNCT
bjp-23039	299	5	2007	2007	NUM
bjp-23039	299	6	;	;	PUNCT
bjp-23039	299	7	13	13	NUM
bjp-23039	299	8	:	:	PUNCT
bjp-23039	299	9	789	789	NUM
bjp-23039	299	10	-	-	SYM
bjp-23039	299	11	94	94	NUM
bjp-23039	299	12	.	.	PUNCT
bjp-23039	300	1	genestra	genestra	PROPN
bjp-23039	300	2	m.	m.	NOUN
bjp-23039	300	3	oxyl	oxyl	PROPN
bjp-23039	300	4	radicals	radical	NOUN
bjp-23039	300	5	,	,	PUNCT
bjp-23039	300	6	redox	redox	NOUN
bjp-23039	300	7	-	-	PUNCT
bjp-23039	300	8	sensitive	sensitive	ADJ
bjp-23039	300	9	signalling	signal	VERB
bjp-23039	300	10	cascades	cascade	NOUN
bjp-23039	300	11	and	and	CCONJ
bjp-23039	300	12	antioxidants	antioxidant	NOUN
bjp-23039	300	13	.	.	PUNCT
bjp-23039	301	1	cell	cell	NOUN
bjp-23039	301	2	signal	signal	NOUN
bjp-23039	301	3	2007	2007	NUM
bjp-23039	301	4	;	;	PUNCT
bjp-23039	301	5	19	19	NUM
bjp-23039	301	6	:	:	SYM
bjp-23039	301	7	1807	1807	NUM
bjp-23039	301	8	-	-	SYM
bjp-23039	301	9	19	19	NUM
bjp-23039	301	10	.	.	PUNCT
bjp-23039	302	1	gottlieb	gottlieb	PROPN
bjp-23039	302	2	e	e	PROPN
bjp-23039	302	3	,	,	PUNCT
bjp-23039	302	4	vander	vander	PROPN
bjp-23039	302	5	heiden	heiden	PROPN
bjp-23039	302	6	mg	mg	PROPN
bjp-23039	302	7	,	,	PUNCT
bjp-23039	302	8	thompson	thompson	PROPN
bjp-23039	302	9	cb	cb	PROPN
bjp-23039	302	10	.	.	PUNCT
bjp-23039	303	1	bcl	bcl	PROPN
bjp-23039	303	2	-	-	PROPN
bjp-23039	303	3	xl	xl	PROPN
bjp-23039	303	4	prevents	prevent	VERB
bjp-23039	303	5	the	the	DET
bjp-23039	303	6	initial	initial	ADJ
bjp-23039	303	7	decrease	decrease	NOUN
bjp-23039	303	8	in	in	ADP
bjp-23039	303	9	mitochondrial	mitochondrial	ADJ
bjp-23039	303	10	membrane	membrane	NOUN
bjp-23039	303	11	potential	potential	NOUN
bjp-23039	303	12	and	and	CCONJ
bjp-23039	303	13	subsequent	subsequent	ADJ
bjp-23039	303	14	reactive	reactive	ADJ
bjp-23039	303	15	oxygen	oxygen	NOUN
bjp-23039	303	16	species	species	NOUN
bjp-23039	303	17	production	production	NOUN
bjp-23039	303	18	during	during	ADP
bjp-23039	303	19	tumor	tumor	NOUN
bjp-23039	303	20	necrosis	necrosis	NOUN
bjp-23039	303	21	factor	factor	NOUN
bjp-23039	303	22	alpha	alpha	NOUN
bjp-23039	303	23	-	-	PUNCT
bjp-23039	303	24	induced	induce	VERB
bjp-23039	303	25	apoptosis	apoptosis	NOUN
bjp-23039	303	26	.	.	PUNCT
bjp-23039	304	1	mol	mol	ADP
bjp-23039	304	2	cell	cell	NOUN
bjp-23039	304	3	biol	biol	NOUN
bjp-23039	304	4	.	.	PUNCT
bjp-23039	305	1	2000	2000	NUM
bjp-23039	305	2	;	;	PUNCT
bjp-23039	305	3	20	20	NUM
bjp-23039	305	4	:	:	SYM
bjp-23039	305	5	5680	5680	NUM
bjp-23039	305	6	-	-	SYM
bjp-23039	305	7	89	89	NUM
bjp-23039	305	8	.	.	PUNCT
bjp-23039	306	1	gross	gross	INTJ
bjp-23039	306	2	a	a	PROPN
bjp-23039	306	3	,	,	PUNCT
bjp-23039	306	4	mcdonnell	mcdonnell	PROPN
bjp-23039	306	5	jm	jm	PROPN
bjp-23039	306	6	,	,	PUNCT
bjp-23039	306	7	korsmeyer	korsmeyer	PROPN
bjp-23039	306	8	sj	sj	PROPN
bjp-23039	306	9	.	.	PUNCT
bjp-23039	306	10	bcl-2	bcl-2	PROPN
bjp-23039	306	11	family	family	NOUN
bjp-23039	306	12	members	member	NOUN
bjp-23039	306	13	and	and	CCONJ
bjp-23039	306	14	the	the	DET
bjp-23039	306	15	mitochondria	mitochondria	NOUN
bjp-23039	306	16	in	in	ADP
bjp-23039	306	17	apoptosis	apoptosis	NOUN
bjp-23039	306	18	.	.	PUNCT
bjp-23039	307	1	genes	gene	NOUN
bjp-23039	307	2	develop	develop	VERB
bjp-23039	307	3	.	.	PUNCT
bjp-23039	308	1	1999	1999	NUM
bjp-23039	308	2	;	;	PUNCT
bjp-23039	308	3	13	13	NUM
bjp-23039	308	4	:	:	SYM
bjp-23039	308	5	1899	1899	NUM
bjp-23039	308	6	-	-	SYM
bjp-23039	308	7	911	911	NUM
bjp-23039	308	8	.	.	PUNCT
bjp-23039	309	1	guijarro	guijarro	PROPN
bjp-23039	309	2	mv	mv	PROPN
bjp-23039	309	3	,	,	PUNCT
bjp-23039	309	4	ghivizzani	ghivizzani	PROPN
bjp-23039	309	5	sc	sc	PROPN
bjp-23039	309	6	,	,	PUNCT
bjp-23039	309	7	gibbs	gibbs	PROPN
bjp-23039	309	8	cp	cp	PROPN
bjp-23039	309	9	.	.	PROPN
bjp-23039	309	10	animal	animal	NOUN
bjp-23039	309	11	models	model	NOUN
bjp-23039	309	12	in	in	ADP
bjp-23039	309	13	osteosarcoma	osteosarcoma	NOUN
bjp-23039	309	14	.	.	PUNCT
bjp-23039	310	1	front	front	ADJ
bjp-23039	310	2	oncol	oncol	ADJ
bjp-23039	310	3	.	.	PUNCT
bjp-23039	311	1	2014	2014	NUM
bjp-23039	311	2	;	;	PUNCT
bjp-23039	311	3	4	4	NUM
bjp-23039	311	4	:	:	SYM
bjp-23039	311	5	189	189	NUM
bjp-23039	311	6	.	.	PUNCT
bjp-23039	311	7	gyrd	gyrd	PROPN
bjp-23039	311	8	-	-	PUNCT
bjp-23039	311	9	hansen	hansen	PROPN
bjp-23039	311	10	m	m	PROPN
bjp-23039	311	11	,	,	PUNCT
bjp-23039	311	12	meier	meier	PROPN
bjp-23039	311	13	p.	p.	PROPN
bjp-23039	312	1	iaps	iap	VERB
bjp-23039	312	2	:	:	PUNCT
bjp-23039	312	3	from	from	ADP
bjp-23039	312	4	caspase	caspase	NOUN
bjp-23039	312	5	inhibitors	inhibitor	NOUN
bjp-23039	312	6	to	to	ADP
bjp-23039	312	7	modulators	modulator	NOUN
bjp-23039	312	8	of	of	ADP
bjp-23039	312	9	nf	nf	ADJ
bjp-23039	312	10	-	-	PUNCT
bjp-23039	312	11	kappab	kappab	NOUN
bjp-23039	312	12	inflammation	inflammation	NOUN
bjp-23039	312	13	and	and	CCONJ
bjp-23039	312	14	cancer	cancer	NOUN
bjp-23039	312	15	.	.	PUNCT
bjp-23039	313	1	nature	nature	NOUN
bjp-23039	313	2	rev	rev	VERB
bjp-23039	313	3	cancer	cancer	NOUN
bjp-23039	313	4	.	.	PUNCT
bjp-23039	314	1	2010	2010	NUM
bjp-23039	314	2	;	;	PUNCT
bjp-23039	314	3	10	10	NUM
bjp-23039	314	4	:	:	SYM
bjp-23039	314	5	561	561	NUM
bjp-23039	314	6	-	-	SYM
bjp-23039	314	7	74	74	NUM
bjp-23039	314	8	.	.	PUNCT
bjp-23039	315	1	haddad	haddad	PROPN
bjp-23039	315	2	aq	aq	PROPN
bjp-23039	315	3	,	,	PUNCT
bjp-23039	315	4	venkateswaran	venkateswaran	VERB
bjp-23039	315	5	v	v	ADP
bjp-23039	315	6	,	,	PUNCT
bjp-23039	315	7	viswanathan	viswanathan	PROPN
bjp-23039	315	8	l	l	PROPN
bjp-23039	315	9	,	,	PUNCT
bjp-23039	315	10	teahan	teahan	ADP
bjp-23039	315	11	sj	sj	PROPN
bjp-23039	315	12	,	,	PUNCT
bjp-23039	315	13	fleshner	fleshner	NOUN
bjp-23039	315	14	ne	ne	PROPN
bjp-23039	315	15	,	,	PUNCT
bjp-23039	315	16	klotz	klotz	PROPN
bjp-23039	315	17	lh	lh	PROPN
bjp-23039	315	18	.	.	PUNCT
bjp-23039	316	1	novel	novel	ADJ
bjp-23039	316	2	antiproliferative	antiproliferative	NOUN
bjp-23039	316	3	flavonoids	flavonoid	NOUN
bjp-23039	316	4	induce	induce	VERB
bjp-23039	316	5	cell	cell	NOUN
bjp-23039	316	6	cycle	cycle	NOUN
bjp-23039	316	7	arrest	arrest	NOUN
bjp-23039	316	8	in	in	ADP
bjp-23039	316	9	human	human	ADJ
bjp-23039	316	10	prostate	prostate	NOUN
bjp-23039	316	11	cancer	cancer	NOUN
bjp-23039	316	12	cell	cell	NOUN
bjp-23039	316	13	lines	line	NOUN
bjp-23039	316	14	.	.	PUNCT
bjp-23039	317	1	prostate	prostate	NOUN
bjp-23039	317	2	cancer	cancer	NOUN
bjp-23039	317	3	prostatic	prostatic	ADJ
bjp-23039	317	4	dis	dis	PROPN
bjp-23039	317	5	.	.	PUNCT
bjp-23039	318	1	2006	2006	NUM
bjp-23039	318	2	;	;	PUNCT
bjp-23039	318	3	9	9	NUM
bjp-23039	318	4	:	:	SYM
bjp-23039	318	5	68	68	NUM
bjp-23039	318	6	-	-	SYM
bjp-23039	318	7	76	76	NUM
bjp-23039	318	8	.	.	PUNCT
bjp-23039	319	1	han	han	PROPN
bjp-23039	319	2	j	j	PROPN
bjp-23039	319	3	,	,	PUNCT
bjp-23039	319	4	goldstein	goldstein	PROPN
bjp-23039	319	5	la	la	PROPN
bjp-23039	319	6	,	,	PUNCT
bjp-23039	319	7	gastman	gastman	NOUN
bjp-23039	319	8	br	br	PROPN
bjp-23039	319	9	,	,	PUNCT
bjp-23039	319	10	rabinowich	rabinowich	PROPN
bjp-23039	319	11	h.	h.	PROPN
bjp-23039	319	12	interrelated	interrelate	VERB
bjp-23039	319	13	roles	role	NOUN
bjp-23039	319	14	for	for	ADP
bjp-23039	319	15	mcl-1	mcl-1	PRON
bjp-23039	319	16	and	and	CCONJ
bjp-23039	319	17	bim	bim	NOUN
bjp-23039	319	18	in	in	ADP
bjp-23039	319	19	regulation	regulation	NOUN
bjp-23039	319	20	of	of	ADP
bjp-23039	319	21	trail	trail	NOUN
bjp-23039	319	22	-	-	PUNCT
bjp-23039	319	23	mediated	mediate	VERB
bjp-23039	319	24	mitochondrial	mitochondrial	ADJ
bjp-23039	319	25	apoptosis	apoptosis	NOUN
bjp-23039	319	26	.	.	PUNCT
bjp-23039	320	1	j	j	PROPN
bjp-23039	320	2	biol	biol	PROPN
bjp-23039	320	3	chem	chem	NOUN
bjp-23039	320	4	.	.	PUNCT
bjp-23039	321	1	2006	2006	NUM
bjp-23039	321	2	;	;	PUNCT
bjp-23039	321	3	281	281	NUM
bjp-23039	321	4	:	:	PUNCT
bjp-23039	321	5	10153	10153	NUM
bjp-23039	321	6	-	-	SYM
bjp-23039	321	7	63	63	NUM
bjp-23039	321	8	.	.	PUNCT
bjp-23039	322	1	hartojo	hartojo	PROPN
bjp-23039	322	2	w	w	PROPN
bjp-23039	322	3	,	,	PUNCT
bjp-23039	322	4	silvers	silvers	PROPN
bjp-23039	322	5	al	al	PROPN
bjp-23039	322	6	,	,	PUNCT
bjp-23039	322	7	thomas	thomas	PROPN
bjp-23039	322	8	dg	dg	PROPN
bjp-23039	322	9	,	,	PUNCT
bjp-23039	322	10	seder	seder	NOUN
bjp-23039	322	11	cw	cw	NOUN
bjp-23039	322	12	,	,	PUNCT
bjp-23039	322	13	lin	lin	PROPN
bjp-23039	322	14	l	l	PROPN
bjp-23039	322	15	,	,	PUNCT
bjp-23039	322	16	rao	rao	PROPN
bjp-23039	322	17	h	h	NOUN
bjp-23039	322	18	,	,	PUNCT
bjp-23039	322	19	wang	wang	PROPN
bjp-23039	322	20	z	z	PROPN
bjp-23039	322	21	,	,	PUNCT
bjp-23039	322	22	greenson	greenson	PROPN
bjp-23039	322	23	jk	jk	PROPN
bjp-23039	322	24	,	,	PUNCT
bjp-23039	322	25	giordano	giordano	PROPN
bjp-23039	322	26	tj	tj	PROPN
bjp-23039	322	27	,	,	PUNCT
bjp-23039	322	28	orringer	orringer	ADJ
bjp-23039	322	29	mb	mb	NOUN
bjp-23039	322	30	,	,	PUNCT
bjp-23039	322	31	rehemtulla	rehemtulla	NOUN
bjp-23039	322	32	a	a	NOUN
bjp-23039	322	33	,	,	PUNCT
bjp-23039	322	34	bhojani	bhojani	ADJ
bjp-23039	322	35	ms	ms	PROPN
bjp-23039	322	36	,	,	PUNCT
bjp-23039	322	37	beer	beer	NOUN
bjp-23039	322	38	dg	dg	PROPN
bjp-23039	322	39	,	,	PUNCT
bjp-23039	322	40	chang	chang	PROPN
bjp-23039	322	41	ac	ac	PROPN
bjp-23039	322	42	.	.	PUNCT
bjp-23039	323	1	curcumin	curcumin	PROPN
bjp-23039	323	2	promotes	promote	VERB
bjp-23039	323	3	apoptosis	apoptosis	NOUN
bjp-23039	323	4	,	,	PUNCT
bjp-23039	323	5	increases	increase	VERB
bjp-23039	323	6	chemosensitivity	chemosensitivity	NOUN
bjp-23039	323	7	,	,	PUNCT
bjp-23039	323	8	and	and	CCONJ
bjp-23039	323	9	inhibits	inhibit	VERB
bjp-23039	323	10	nuclear	nuclear	ADJ
bjp-23039	323	11	factor	factor	NOUN
bjp-23039	323	12	kappab	kappab	NOUN
bjp-23039	323	13	in	in	ADP
bjp-23039	323	14	esophageal	esophageal	ADJ
bjp-23039	323	15	adenocarcinoma	adenocarcinoma	NOUN
bjp-23039	323	16	.	.	PUNCT
bjp-23039	324	1	transl	transl	PROPN
bjp-23039	324	2	oncol	oncol	PROPN
bjp-23039	324	3	.	.	PUNCT
bjp-23039	325	1	2010	2010	NUM
bjp-23039	325	2	;	;	PUNCT
bjp-23039	325	3	3	3	NUM
bjp-23039	325	4	:	:	SYM
bjp-23039	325	5	99	99	NUM
bjp-23039	325	6	-	-	SYM
bjp-23039	325	7	108	108	NUM
bjp-23039	325	8	.	.	PUNCT
bjp-23039	326	1	heath	heath	PROPN
bjp-23039	326	2	-	-	PUNCT
bjp-23039	326	3	engel	engel	PROPN
bjp-23039	326	4	hm	hm	PROPN
bjp-23039	326	5	,	,	PUNCT
bjp-23039	326	6	chang	chang	PROPN
bjp-23039	326	7	nc	nc	PROPN
bjp-23039	326	8	,	,	PUNCT
bjp-23039	326	9	shore	shore	PROPN
bjp-23039	326	10	gc	gc	PROPN
bjp-23039	326	11	.	.	PUNCT
bjp-23039	327	1	the	the	DET
bjp-23039	327	2	endoplasmic	endoplasmic	ADJ
bjp-23039	327	3	reticulum	reticulum	NOUN
bjp-23039	327	4	in	in	ADP
bjp-23039	327	5	apoptosis	apoptosis	NOUN
bjp-23039	327	6	and	and	CCONJ
bjp-23039	327	7	autophagy	autophagy	NOUN
bjp-23039	327	8	:	:	PUNCT
bjp-23039	327	9	role	role	NOUN
bjp-23039	327	10	of	of	ADP
bjp-23039	327	11	the	the	DET
bjp-23039	327	12	bcl-2	bcl-2	PUNCT
bjp-23039	327	13	protein	protein	NOUN
bjp-23039	327	14	family	family	NOUN
bjp-23039	327	15	.	.	PUNCT
bjp-23039	328	1	oncogene	oncogene	NOUN
bjp-23039	328	2	2008	2008	NUM
bjp-23039	328	3	;	;	PUNCT
bjp-23039	328	4	27	27	NUM
bjp-23039	328	5	:	:	PUNCT
bjp-23039	328	6	6419	6419	NUM
bjp-23039	328	7	-	-	SYM
bjp-23039	328	8	33	33	NUM
bjp-23039	328	9	.	.	PUNCT
bjp-23039	329	1	hunter	hunter	PROPN
bjp-23039	329	2	am	am	PROPN
bjp-23039	329	3	,	,	PUNCT
bjp-23039	329	4	lacasse	lacasse	PROPN
bjp-23039	329	5	ec	ec	PROPN
bjp-23039	329	6	,	,	PUNCT
bjp-23039	329	7	korneluk	korneluk	PROPN
bjp-23039	329	8	rg	rg	PROPN
bjp-23039	329	9	.	.	PUNCT
bjp-23039	330	1	the	the	DET
bjp-23039	330	2	inhibitors	inhibitor	NOUN
bjp-23039	330	3	of	of	ADP
bjp-23039	330	4	apoptosis	apoptosis	NOUN
bjp-23039	330	5	(	(	PUNCT
bjp-23039	330	6	iaps	iap	NOUN
bjp-23039	330	7	)	)	PUNCT
bjp-23039	330	8	as	as	ADP
bjp-23039	330	9	cancer	cancer	NOUN
bjp-23039	330	10	targets	target	NOUN
bjp-23039	330	11	.	.	PUNCT
bjp-23039	331	1	apoptosis	apoptosis	NOUN
bjp-23039	331	2	2007	2007	NUM
bjp-23039	331	3	;	;	PUNCT
bjp-23039	331	4	12	12	NUM
bjp-23039	331	5	:	:	SYM
bjp-23039	331	6	154368	154368	NUM
bjp-23039	331	7	.	.	PUNCT
bjp-23039	332	1	huttemann	huttemann	PROPN
bjp-23039	332	2	m	m	PROPN
bjp-23039	332	3	,	,	PUNCT
bjp-23039	332	4	pecina	pecina	PROPN
bjp-23039	332	5	p	p	NOUN
bjp-23039	332	6	,	,	PUNCT
bjp-23039	332	7	rainbolt	rainbolt	VERB
bjp-23039	332	8	m	m	PRON
bjp-23039	332	9	,	,	PUNCT
bjp-23039	332	10	sanderson	sanderson	PROPN
bjp-23039	332	11	th	th	PROPN
bjp-23039	332	12	,	,	PUNCT
bjp-23039	332	13	kagan	kagan	PROPN
bjp-23039	332	14	ve	ve	PROPN
bjp-23039	332	15	,	,	PUNCT
bjp-23039	332	16	samavati	samavati	NOUN
bjp-23039	332	17	l	l	NOUN
bjp-23039	332	18	,	,	PUNCT
bjp-23039	332	19	doan	doan	PROPN
bjp-23039	332	20	jw	jw	PROPN
bjp-23039	332	21	,	,	PUNCT
bjp-23039	332	22	lee	lee	PROPN
bjp-23039	332	23	i.	i.	PROPN
bjp-23039	332	24	the	the	DET
bjp-23039	332	25	multiple	multiple	ADJ
bjp-23039	332	26	functions	function	NOUN
bjp-23039	332	27	of	of	ADP
bjp-23039	332	28	cytochrome	cytochrome	NOUN
bjp-23039	332	29	c	c	NOUN
bjp-23039	332	30	and	and	CCONJ
bjp-23039	332	31	their	their	PRON
bjp-23039	332	32	regulation	regulation	NOUN
bjp-23039	332	33	in	in	ADP
bjp-23039	332	34	life	life	NOUN
bjp-23039	332	35	and	and	CCONJ
bjp-23039	332	36	death	death	NOUN
bjp-23039	332	37	decisions	decision	NOUN
bjp-23039	332	38	of	of	ADP
bjp-23039	332	39	the	the	DET
bjp-23039	332	40	mammalian	mammalian	ADJ
bjp-23039	332	41	cell	cell	NOUN
bjp-23039	332	42	:	:	PUNCT
bjp-23039	332	43	from	from	ADP
bjp-23039	332	44	respiration	respiration	NOUN
bjp-23039	332	45	to	to	ADP
bjp-23039	332	46	apoptosis	apoptosis	NOUN
bjp-23039	332	47	.	.	PUNCT
bjp-23039	333	1	mitochondrion	mitochondrion	NOUN
bjp-23039	333	2	2011	2011	NUM
bjp-23039	333	3	;	;	PUNCT
bjp-23039	333	4	11	11	NUM
bjp-23039	333	5	:	:	SYM
bjp-23039	333	6	369	369	NUM
bjp-23039	333	7	-	-	SYM
bjp-23039	333	8	81	81	NUM
bjp-23039	333	9	.	.	PUNCT
bjp-23039	334	1	ishikawa	ishikawa	PROPN
bjp-23039	334	2	y	y	PROPN
bjp-23039	334	3	,	,	PUNCT
bjp-23039	334	4	kitamura	kitamura	PROPN
bjp-23039	334	5	m.	m.	PROPN
bjp-23039	334	6	dual	dual	ADJ
bjp-23039	334	7	potential	potential	NOUN
bjp-23039	334	8	of	of	ADP
bjp-23039	334	9	extracellular	extracellular	ADJ
bjp-23039	334	10	signalregulated	signalregulate	VERB
bjp-23039	334	11	kinase	kinase	NOUN
bjp-23039	334	12	for	for	ADP
bjp-23039	334	13	the	the	DET
bjp-23039	334	14	control	control	NOUN
bjp-23039	334	15	of	of	ADP
bjp-23039	334	16	cell	cell	NOUN
bjp-23039	334	17	survival	survival	NOUN
bjp-23039	334	18	.	.	PUNCT
bjp-23039	335	1	biochem	biochem	PROPN
bjp-23039	335	2	biophy	biophy	NOUN
bjp-23039	335	3	res	re	NOUN
bjp-23039	335	4	commun	commun	PROPN
bjp-23039	335	5	.	.	PUNCT
bjp-23039	336	1	1999	1999	NUM
bjp-23039	336	2	;	;	PUNCT
bjp-23039	336	3	264	264	NUM
bjp-23039	336	4	:	:	PUNCT
bjp-23039	336	5	696	696	NUM
bjp-23039	336	6	-	-	SYM
bjp-23039	336	7	701	701	NUM
bjp-23039	336	8	.	.	PUNCT
bjp-23039	336	9	johnson	johnson	PROPN
bjp-23039	336	10	gl	gl	PROPN
bjp-23039	336	11	,	,	PUNCT
bjp-23039	336	12	lapadat	lapadat	PROPN
bjp-23039	336	13	r.	r.	PROPN
bjp-23039	336	14	mitogen	mitogen	PROPN
bjp-23039	336	15	-	-	PUNCT
bjp-23039	336	16	activated	activate	VERB
bjp-23039	336	17	protein	protein	NOUN
bjp-23039	336	18	kinase	kinase	NOUN
bjp-23039	336	19	pathways	pathway	NOUN
bjp-23039	336	20	mediated	mediate	VERB
bjp-23039	336	21	by	by	ADP
bjp-23039	336	22	erk	erk	PROPN
bjp-23039	336	23	,	,	PUNCT
bjp-23039	336	24	jnk	jnk	PROPN
bjp-23039	336	25	,	,	PUNCT
bjp-23039	336	26	and	and	CCONJ
bjp-23039	336	27	p38	p38	NOUN
bjp-23039	336	28	protein	protein	NOUN
bjp-23039	336	29	kinases	kinase	NOUN
bjp-23039	336	30	.	.	PUNCT
bjp-23039	337	1	science	science	NOUN
bjp-23039	337	2	2002	2002	NUM
bjp-23039	337	3	;	;	PUNCT
bjp-23039	337	4	298	298	NUM
bjp-23039	337	5	:	:	PUNCT
bjp-23039	337	6	1911	1911	NUM
bjp-23039	337	7	-	-	SYM
bjp-23039	337	8	12	12	NUM
bjp-23039	337	9	.	.	PUNCT
bjp-23039	338	1	kager	kager	PROPN
bjp-23039	338	2	l	l	PROPN
bjp-23039	338	3	,	,	PUNCT
bjp-23039	338	4	zoubek	zoubek	PROPN
bjp-23039	338	5	a	a	X
bjp-23039	338	6	,	,	PUNCT
bjp-23039	338	7	potschger	potschger	NOUN
bjp-23039	338	8	u	u	PROPN
bjp-23039	338	9	,	,	PUNCT
bjp-23039	338	10	kastner	kastner	PROPN
bjp-23039	338	11	u	u	PROPN
bjp-23039	338	12	,	,	PUNCT
bjp-23039	338	13	flege	flege	PROPN
bjp-23039	338	14	s	s	PROPN
bjp-23039	338	15	,	,	PUNCT
bjp-23039	338	16	kempf‑bielack	kempf‑bielack	NOUN
bjp-23039	338	17	b	b	NOUN
bjp-23039	338	18	,	,	PUNCT
bjp-23039	338	19	branscheid	branscheid	PROPN
bjp-23039	338	20	d	d	PROPN
bjp-23039	338	21	,	,	PUNCT
bjp-23039	338	22	kotz	kotz	PROPN
bjp-23039	338	23	r	r	PROPN
bjp-23039	338	24	,	,	PUNCT
bjp-23039	338	25	salzer	salzer	NOUN
bjp-23039	338	26	-	-	PUNCT
bjp-23039	338	27	kuntschik	kuntschik	NOUN
bjp-23039	338	28	m	m	PROPN
bjp-23039	338	29	,	,	PUNCT
bjp-23039	338	30	winkelmann	winkelmann	PROPN
bjp-23039	338	31	w	w	PROPN
bjp-23039	338	32	,	,	PUNCT
bjp-23039	338	33	jundt	jundt	ADV
bjp-23039	338	34	g	g	PROPN
bjp-23039	338	35	,	,	PUNCT
bjp-23039	338	36	kabisch	kabisch	PROPN
bjp-23039	338	37	h	h	PROPN
bjp-23039	338	38	,	,	PUNCT
bjp-23039	338	39	reichardt	reichardt	PROPN
bjp-23039	338	40	p	p	NOUN
bjp-23039	338	41	,	,	PUNCT
bjp-23039	338	42	jurgens	jurgens	PROPN
bjp-23039	338	43	h	h	PROPN
bjp-23039	338	44	,	,	PUNCT
bjp-23039	338	45	gadner	gadner	NOUN
bjp-23039	338	46	h	h	NOUN
bjp-23039	338	47	,	,	PUNCT
bjp-23039	338	48	bielack	bielack	ADJ
bjp-23039	338	49	ss	ss	PROPN
bjp-23039	338	50	.	.	PUNCT
bjp-23039	339	1	primary	primary	ADJ
bjp-23039	339	2	metastatic	metastatic	ADJ
bjp-23039	339	3	osteosarcoma	osteosarcoma	NOUN
bjp-23039	339	4	:	:	PUNCT
bjp-23039	339	5	presentation	presentation	NOUN
bjp-23039	339	6	and	and	CCONJ
bjp-23039	339	7	outcome	outcome	NOUN
bjp-23039	339	8	of	of	ADP
bjp-23039	339	9	patients	patient	NOUN
bjp-23039	339	10	treated	treat	VERB
bjp-23039	339	11	on	on	ADP
bjp-23039	339	12	neoadjuvant	neoadjuvant	ADJ
bjp-23039	339	13	cooperative	cooperative	ADJ
bjp-23039	339	14	osteosarcoma	osteosarcoma	ADJ
bjp-23039	339	15	study	study	NOUN
bjp-23039	339	16	group	group	NOUN
bjp-23039	339	17	protocols	protocol	NOUN
bjp-23039	339	18	.	.	PUNCT
bjp-23039	340	1	j	j	PROPN
bjp-23039	340	2	clin	clin	PROPN
bjp-23039	340	3	oncol	oncol	PROPN
bjp-23039	340	4	.	.	PUNCT
bjp-23039	341	1	2003	2003	NUM
bjp-23039	341	2	;	;	PUNCT
bjp-23039	341	3	21	21	NUM
bjp-23039	341	4	:	:	PUNCT
bjp-23039	341	5	2011	2011	NUM
bjp-23039	341	6	-	-	SYM
bjp-23039	341	7	18	18	NUM
bjp-23039	341	8	.	.	PUNCT
bjp-23039	342	1	kim	kim	PROPN
bjp-23039	342	2	bm	bm	PROPN
bjp-23039	342	3	,	,	PUNCT
bjp-23039	342	4	chung	chung	PROPN
bjp-23039	342	5	hw	hw	AUX
bjp-23039	342	6	.	.	PROPN
bjp-23039	342	7	desferrioxamine	desferrioxamine	PROPN
bjp-23039	342	8	(	(	PUNCT
bjp-23039	342	9	dfx	dfx	NOUN
bjp-23039	342	10	)	)	PUNCT
bjp-23039	342	11	induces	induce	VERB
bjp-23039	342	12	apoptosis	apoptosis	NOUN
bjp-23039	342	13	through	through	ADP
bjp-23039	342	14	the	the	DET
bjp-23039	342	15	p38	p38	NOUN
bjp-23039	342	16	-	-	PUNCT
bjp-23039	342	17	caspase8bid	caspase8bid	NOUN
bjp-23039	342	18	-	-	PUNCT
bjp-23039	342	19	bax	bax	NOUN
bjp-23039	342	20	pathway	pathway	NOUN
bjp-23039	342	21	in	in	ADP
bjp-23039	342	22	pha	pha	PROPN
bjp-23039	342	23	stimulated	stimulate	VERB
bjp-23039	342	24	human	human	ADJ
bjp-23039	342	25	lymphocytes	lymphocyte	NOUN
bjp-23039	342	26	.	.	PUNCT
bjp-23039	343	1	toxicol	toxicol	PROPN
bjp-23039	343	2	appl	appl	PROPN
bjp-23039	343	3	pharmacol	pharmacol	PROPN
bjp-23039	343	4	.	.	PUNCT
bjp-23039	343	5	2008	2008	NUM
bjp-23039	343	6	;	;	PUNCT
bjp-23039	343	7	228	228	NUM
bjp-23039	343	8	:	:	PUNCT
bjp-23039	343	9	24	24	NUM
bjp-23039	343	10	-	-	SYM
bjp-23039	343	11	31	31	NUM
bjp-23039	343	12	.	.	PUNCT
bjp-23039	344	1	kim	kim	PROPN
bjp-23039	344	2	sj	sj	PROPN
bjp-23039	344	3	,	,	PUNCT
bjp-23039	344	4	choi	choi	PROPN
bjp-23039	344	5	ja	ja	PROPN
bjp-23039	344	6	,	,	PUNCT
bjp-23039	344	7	lee	lee	PROPN
bjp-23039	344	8	sh	sh	PROPN
bjp-23039	344	9	,	,	PUNCT
bjp-23039	344	10	choi	choi	PROPN
bjp-23039	344	11	jy	jy	PROPN
bjp-23039	344	12	,	,	PUNCT
bjp-23039	344	13	hong	hong	PROPN
bjp-23039	344	14	sh	sh	PROPN
bjp-23039	344	15	,	,	PUNCT
bjp-23039	344	16	chung	chung	PROPN
bjp-23039	344	17	hw	hw	PROPN
bjp-23039	344	18	and	and	CCONJ
bjp-23039	344	19	kang	kang	PROPN
bjp-23039	344	20	hs	hs	PROPN
bjp-23039	344	21	.	.	PROPN
bjp-23039	344	22	imaging	imaging	PROPN
bjp-23039	344	23	findings	finding	NOUN
bjp-23039	344	24	of	of	ADP
bjp-23039	344	25	extrapulmonary	extrapulmonary	ADJ
bjp-23039	344	26	metastases	metastasis	NOUN
bjp-23039	344	27	of	of	ADP
bjp-23039	344	28	osteosarcoma	osteosarcoma	NOUN
bjp-23039	344	29	.	.	PUNCT
bjp-23039	345	1	clin	clin	PROPN
bjp-23039	345	2	imaging	imaging	PROPN
bjp-23039	345	3	.	.	PUNCT
bjp-23039	346	1	2004	2004	NUM
bjp-23039	346	2	;	;	PUNCT
bjp-23039	346	3	28	28	NUM
bjp-23039	346	4	:	:	PUNCT
bjp-23039	346	5	291	291	NUM
bjp-23039	346	6	-	-	SYM
bjp-23039	346	7	300	300	NUM
bjp-23039	346	8	.	.	PUNCT
bjp-23039	347	1	kim	kim	PROPN
bjp-23039	347	2	hj	hj	PROPN
bjp-23039	347	3	,	,	PUNCT
bjp-23039	347	4	kim	kim	PROPN
bjp-23039	347	5	sh	sh	PROPN
bjp-23039	347	6	,	,	PUNCT
bjp-23039	347	7	yun	yun	PROPN
bjp-23039	347	8	j	j	PROPN
bjp-23039	347	9	-	-	PUNCT
bjp-23039	347	10	m.	m.	NOUN
bjp-23039	347	11	fisetin	fisetin	NOUN
bjp-23039	347	12	inhibits	inhibit	VERB
bjp-23039	347	13	hyperglycemiainduced	hyperglycemiainduce	VERB
bjp-23039	347	14	proinflammatory	proinflammatory	ADJ
bjp-23039	347	15	cytokine	cytokine	NOUN
bjp-23039	347	16	production	production	NOUN
bjp-23039	347	17	by	by	ADP
bjp-23039	347	18	epigenetic	epigenetic	ADJ
bjp-23039	347	19	mechanisms	mechanism	NOUN
bjp-23039	347	20	.	.	PUNCT
bjp-23039	348	1	evid	evid	PROPN
bjp-23039	348	2	based	base	VERB
bjp-23039	348	3	complement	complement	PROPN
bjp-23039	348	4	alternat	alternat	NOUN
bjp-23039	348	5	med	me	VERB
bjp-23039	348	6	.	.	PROPN
bjp-23039	348	7	2012	2012	NUM
bjp-23039	348	8	;	;	PUNCT
bjp-23039	348	9	2012	2012	NUM
bjp-23039	348	10	:	:	PUNCT
bjp-23039	348	11	639469	639469	NUM
bjp-23039	348	12	klaunig	klaunig	PROPN
bjp-23039	348	13	je	je	PROPN
bjp-23039	348	14	,	,	PUNCT
bjp-23039	348	15	kamendulis	kamendulis	X
bjp-23039	348	16	lm	lm	INTJ
bjp-23039	348	17	,	,	PUNCT
bjp-23039	348	18	hocevar	hocevar	PROPN
bjp-23039	348	19	ba	ba	PROPN
bjp-23039	348	20	.	.	PUNCT
bjp-23039	348	21	oxidative	oxidative	ADJ
bjp-23039	348	22	stress	stress	NOUN
bjp-23039	348	23	and	and	CCONJ
bjp-23039	348	24	oxidative	oxidative	ADJ
bjp-23039	348	25	damage	damage	NOUN
bjp-23039	348	26	in	in	ADP
bjp-23039	348	27	carcinogenesis	carcinogenesis	NOUN
bjp-23039	348	28	.	.	PUNCT
bjp-23039	349	1	toxicologic	toxicologic	NOUN
bjp-23039	349	2	pathol	pathol	NOUN
bjp-23039	349	3	.	.	PUNCT
bjp-23039	350	1	2010	2010	NUM
bjp-23039	350	2	;	;	PUNCT
bjp-23039	350	3	38	38	NUM
bjp-23039	350	4	:	:	SYM
bjp-23039	350	5	96	96	NUM
bjp-23039	350	6	-	-	SYM
bjp-23039	350	7	109	109	NUM
bjp-23039	350	8	.	.	PUNCT
bjp-23039	351	1	kroemer	kroemer	PROPN
bjp-23039	351	2	g	g	PROPN
bjp-23039	351	3	,	,	PUNCT
bjp-23039	351	4	galluzzi	galluzzi	NOUN
bjp-23039	351	5	l	l	NOUN
bjp-23039	351	6	,	,	PUNCT
bjp-23039	351	7	brenner	brenner	PROPN
bjp-23039	351	8	c.	c.	PROPN
bjp-23039	351	9	mitochondrial	mitochondrial	ADJ
bjp-23039	351	10	membrane	membrane	NOUN
bjp-23039	351	11	permeabilization	permeabilization	NOUN
bjp-23039	351	12	in	in	ADP
bjp-23039	351	13	cell	cell	NOUN
bjp-23039	351	14	death	death	NOUN
bjp-23039	351	15	.	.	PUNCT
bjp-23039	352	1	physiol	physiol	PROPN
bjp-23039	352	2	rev	rev	VERB
bjp-23039	352	3	.	.	PROPN
bjp-23039	352	4	2007	2007	NUM
bjp-23039	352	5	;	;	PUNCT
bjp-23039	352	6	87	87	NUM
bjp-23039	352	7	:	:	SYM
bjp-23039	352	8	99	99	NUM
bjp-23039	352	9	-	-	SYM
bjp-23039	352	10	163	163	NUM
bjp-23039	352	11	.	.	PUNCT
bjp-23039	353	1	lee	lee	PROPN
bjp-23039	353	2	wr	wr	PROPN
bjp-23039	353	3	,	,	PUNCT
bjp-23039	353	4	shen	shen	PROPN
bjp-23039	353	5	sc	sc	PROPN
bjp-23039	353	6	,	,	PUNCT
bjp-23039	353	7	lin	lin	PROPN
bjp-23039	353	8	hy	hy	PROPN
bjp-23039	353	9	,	,	PUNCT
bjp-23039	353	10	hou	hou	PROPN
bjp-23039	353	11	wc	wc	PROPN
bjp-23039	353	12	,	,	PUNCT
bjp-23039	353	13	yang	yang	PROPN
bjp-23039	353	14	ll	ll	PROPN
bjp-23039	353	15	,	,	PUNCT
bjp-23039	353	16	chen	chen	PROPN
bjp-23039	354	1	yc	yc	AUX
bjp-23039	354	2	.	.	PROPN
bjp-23039	354	3	wogonin	wogonin	PROPN
bjp-23039	354	4	and	and	CCONJ
bjp-23039	354	5	fisetin	fisetin	VERB
bjp-23039	354	6	induce	induce	VERB
bjp-23039	354	7	apoptosis	apoptosis	NOUN
bjp-23039	354	8	in	in	ADP
bjp-23039	354	9	human	human	ADJ
bjp-23039	354	10	promyeloleukemic	promyeloleukemic	ADJ
bjp-23039	354	11	cells	cell	NOUN
bjp-23039	354	12	,	,	PUNCT
bjp-23039	354	13	accompanied	accompany	VERB
bjp-23039	354	14	by	by	ADP
bjp-23039	354	15	a	a	DET
bjp-23039	354	16	decrease	decrease	NOUN
bjp-23039	354	17	of	of	ADP
bjp-23039	354	18	reactive	reactive	ADJ
bjp-23039	354	19	oxygen	oxygen	NOUN
bjp-23039	354	20	species	specie	NOUN
bjp-23039	354	21	,	,	PUNCT
bjp-23039	354	22	and	and	CCONJ
bjp-23039	354	23	activation	activation	NOUN
bjp-23039	354	24	of	of	ADP
bjp-23039	354	25	caspase	caspase	PROPN
bjp-23039	354	26	3	3	NUM
bjp-23039	354	27	and	and	CCONJ
bjp-23039	354	28	ca2+dependent	ca2+dependent	ADJ
bjp-23039	354	29	endonuclease	endonuclease	NOUN
bjp-23039	354	30	.	.	PUNCT
bjp-23039	355	1	biochem	biochem	PROPN
bjp-23039	355	2	pharmacol	pharmacol	PROPN
bjp-23039	355	3	.	.	PUNCT
bjp-23039	356	1	2002	2002	NUM
bjp-23039	356	2	;	;	PUNCT
bjp-23039	356	3	63	63	NUM
bjp-23039	356	4	:	:	SYM
bjp-23039	356	5	22536	22536	NUM
bjp-23039	356	6	.	.	PUNCT
bjp-23039	357	1	lee	lee	PROPN
bjp-23039	357	2	hy	hy	PROPN
bjp-23039	357	3	,	,	PUNCT
bjp-23039	357	4	jeon	jeon	PROPN
bjp-23039	357	5	hs	hs	PROPN
bjp-23039	357	6	,	,	PUNCT
bjp-23039	357	7	song	song	PROPN
bjp-23039	357	8	ek	ek	PROPN
bjp-23039	357	9	,	,	PUNCT
bjp-23039	357	10	han	han	PROPN
bjp-23039	357	11	mk	mk	PROPN
bjp-23039	357	12	,	,	PUNCT
bjp-23039	357	13	park	park	NOUN
bjp-23039	357	14	si	si	PROPN
bjp-23039	357	15	,	,	PUNCT
bjp-23039	357	16	lee	lee	PROPN
bjp-23039	357	17	si	si	PROPN
bjp-23039	357	18	,	,	PUNCT
bjp-23039	357	19	yun	yun	PROPN
bjp-23039	357	20	hj	hj	PROPN
bjp-23039	357	21	,	,	PUNCT
bjp-23039	357	22	kim	kim	PROPN
bjp-23039	357	23	jr	jr	PROPN
bjp-23039	357	24	,	,	PUNCT
bjp-23039	357	25	kim	kim	PROPN
bjp-23039	357	26	js	js	PROPN
bjp-23039	357	27	,	,	PUNCT
bjp-23039	357	28	lee	lee	PROPN
bjp-23039	357	29	yc	yc	PROPN
bjp-23039	357	30	,	,	PUNCT
bjp-23039	357	31	kim	kim	PROPN
bjp-23039	357	32	si	si	PROPN
bjp-23039	357	33	,	,	PUNCT
bjp-23039	357	34	kim	kim	PROPN
bjp-23039	357	35	hr	hr	PROPN
bjp-23039	357	36	,	,	PUNCT
bjp-23039	357	37	choi	choi	PROPN
bjp-23039	357	38	jy	jy	PROPN
bjp-23039	357	39	,	,	PUNCT
bjp-23039	357	40	kang	kang	PROPN
bjp-23039	357	41	i	i	PROPN
bjp-23039	357	42	,	,	PUNCT
bjp-23039	357	43	kim	kim	PROPN
bjp-23039	357	44	hy	hy	PROPN
bjp-23039	357	45	,	,	PUNCT
bjp-23039	357	46	yoo	yoo	PROPN
bjp-23039	357	47	wh	wh	PROPN
bjp-23039	357	48	.	.	PUNCT
bjp-23039	358	1	cd40	cd40	PROPN
bjp-23039	358	2	ligation	ligation	NOUN
bjp-23039	358	3	of	of	ADP
bjp-23039	358	4	rheumatoid	rheumatoid	NOUN
bjp-23039	358	5	synovial	synovial	ADJ
bjp-23039	358	6	fibroblasts	fibroblast	NOUN
bjp-23039	358	7	regulates	regulate	VERB
bjp-23039	358	8	rankl	rankl	NOUN
bjp-23039	358	9	-	-	PUNCT
bjp-23039	358	10	mediated	mediate	VERB
bjp-23039	358	11	osteoclastogenesis	osteoclastogenesis	NOUN
bjp-23039	358	12	:	:	PUNCT
bjp-23039	358	13	evidence	evidence	NOUN
bjp-23039	358	14	of	of	ADP
bjp-23039	358	15	nf	nf	ADJ
bjp-23039	358	16	-	-	PUNCT
bjp-23039	358	17	kappab	kappab	NOUN
bjp-23039	358	18	-	-	PUNCT
bjp-23039	358	19	dependent	dependent	ADJ
bjp-23039	358	20	,	,	PUNCT
bjp-23039	358	21	cd40	cd40	PROPN
bjp-23039	358	22	-	-	PUNCT
bjp-23039	358	23	mediated	mediate	VERB
bjp-23039	358	24	bone	bone	NOUN
bjp-23039	358	25	destruction	destruction	NOUN
bjp-23039	358	26	in	in	ADP
bjp-23039	358	27	rheumatoid	rheumatoid	NOUN
bjp-23039	358	28	arthritis	arthritis	NOUN
bjp-23039	358	29	.	.	PUNCT
bjp-23039	359	1	arthritis	arthritis	NOUN
bjp-23039	359	2	rheum	rheum	NOUN
bjp-23039	359	3	.	.	PUNCT
bjp-23039	360	1	2006	2006	NUM
bjp-23039	360	2	;	;	PUNCT
bjp-23039	360	3	54	54	NUM
bjp-23039	360	4	:	:	SYM
bjp-23039	360	5	1747	1747	NUM
bjp-23039	360	6	-	-	SYM
bjp-23039	360	7	58	58	NUM
bjp-23039	360	8	.	.	PUNCT
bjp-23039	361	1	lee	lee	PROPN
bjp-23039	361	2	jc	jc	PROPN
bjp-23039	361	3	,	,	PUNCT
bjp-23039	361	4	son	son	NOUN
bjp-23039	361	5	yo	yo	PROPN
bjp-23039	361	6	,	,	PUNCT
bjp-23039	361	7	pratheeshkumar	pratheeshkumar	PROPN
bjp-23039	361	8	p	p	PROPN
bjp-23039	361	9	,	,	PUNCT
bjp-23039	361	10	shi	shi	PROPN
bjp-23039	361	11	x.	x.	PROPN
bjp-23039	361	12	oxidative	oxidative	ADJ
bjp-23039	361	13	stress	stress	NOUN
bjp-23039	361	14	and	and	CCONJ
bjp-23039	361	15	metal	metal	NOUN
bjp-23039	361	16	carcinogenesis	carcinogenesis	NOUN
bjp-23039	361	17	.	.	PUNCT
bjp-23039	362	1	free	free	ADJ
bjp-23039	362	2	radic	radic	ADJ
bjp-23039	362	3	biol	biol	PROPN
bjp-23039	362	4	med	me	VERB
bjp-23039	362	5	.	.	PUNCT
bjp-23039	362	6	2012	2012	NUM
bjp-23039	362	7	;	;	PUNCT
bjp-23039	362	8	53	53	NUM
bjp-23039	362	9	:	:	SYM
bjp-23039	362	10	742	742	NUM
bjp-23039	362	11	-	-	SYM
bjp-23039	362	12	57	57	NUM
bjp-23039	362	13	.	.	PUNCT
bjp-23039	363	1	lewis	lewis	PROPN
bjp-23039	363	2	ts	ts	PROPN
bjp-23039	363	3	,	,	PUNCT
bjp-23039	363	4	shapiro	shapiro	PROPN
bjp-23039	363	5	ps	ps	PROPN
bjp-23039	363	6	,	,	PUNCT
bjp-23039	363	7	ahn	ahn	PROPN
bjp-23039	363	8	ng	ng	PROPN
bjp-23039	363	9	.	.	PROPN
bjp-23039	363	10	signal	signal	PROPN
bjp-23039	363	11	transduction	transduction	NOUN
bjp-23039	363	12	through	through	ADP
bjp-23039	363	13	map	map	NOUN
bjp-23039	363	14	kinase	kinase	PROPN
bjp-23039	363	15	cascades	cascade	NOUN
bjp-23039	363	16	.	.	PUNCT
bjp-23039	364	1	adv	adv	PROPN
bjp-23039	364	2	cancer	cancer	NOUN
bjp-23039	364	3	res	re	NOUN
bjp-23039	364	4	.	.	PUNCT
bjp-23039	365	1	1998	1998	NUM
bjp-23039	365	2	;	;	PUNCT
bjp-23039	365	3	74	74	NUM
bjp-23039	365	4	:	:	SYM
bjp-23039	365	5	49	49	NUM
bjp-23039	365	6	-	-	SYM
bjp-23039	365	7	139	139	NUM
bjp-23039	365	8	.	.	PUNCT
bjp-23039	366	1	li	li	PROPN
bjp-23039	366	2	j	j	PROPN
bjp-23039	366	3	,	,	PUNCT
bjp-23039	366	4	zhang	zhang	PROPN
bjp-23039	366	5	f	f	PROPN
bjp-23039	366	6	,	,	PUNCT
bjp-23039	366	7	wang	wang	PROPN
bjp-23039	366	8	s.	s.	PROPN
bjp-23039	366	9	a	a	DET
bjp-23039	366	10	polysaccharide	polysaccharide	NOUN
bjp-23039	366	11	from	from	ADP
bjp-23039	366	12	pomegranate	pomegranate	ADJ
bjp-23039	366	13	peels	peel	NOUN
bjp-23039	366	14	induces	induce	VERB
bjp-23039	366	15	the	the	DET
bjp-23039	366	16	apoptosis	apoptosis	NOUN
bjp-23039	366	17	of	of	ADP
bjp-23039	366	18	human	human	ADJ
bjp-23039	366	19	osteosarcoma	osteosarcoma	ADJ
bjp-23039	366	20	cells	cell	NOUN
bjp-23039	366	21	via	via	ADP
bjp-23039	366	22	the	the	DET
bjp-23039	366	23	mitochondrial	mitochondrial	ADJ
bjp-23039	366	24	apoptotic	apoptotic	ADJ
bjp-23039	366	25	pathway	pathway	NOUN
bjp-23039	366	26	.	.	PUNCT
bjp-23039	367	1	tumour	tumour	PROPN
bjp-23039	367	2	biol	biol	PROPN
bjp-23039	367	3	.	.	PUNCT
bjp-23039	368	1	2014	2014	NUM
bjp-23039	368	2	;	;	PUNCT
bjp-23039	368	3	35	35	NUM
bjp-23039	368	4	:	:	SYM
bjp-23039	368	5	7475	7475	NUM
bjp-23039	368	6	-	-	SYM
bjp-23039	368	7	82	82	NUM
bjp-23039	368	8	.	.	NOUN
bjp-23039	368	9	828	828	NUM
bjp-23039	368	10	bangladesh	bangladesh	PROPN
bjp-23039	368	11	j	j	PROPN
bjp-23039	368	12	pharmacol	pharmacol	PROPN
bjp-23039	368	13	2015	2015	NUM
bjp-23039	368	14	;	;	PUNCT
bjp-23039	368	15	10	10	NUM
bjp-23039	368	16	:	:	SYM
bjp-23039	368	17	820	820	NUM
bjp-23039	368	18	-	-	SYM
bjp-23039	368	19	829	829	NUM
bjp-23039	368	20	author	author	NOUN
bjp-23039	368	21	info	info	NOUN
bjp-23039	368	22	jian	jian	PROPN
bjp-23039	368	23	-	-	PUNCT
bjp-23039	368	24	ming	ming	PROPN
bjp-23039	368	25	li	li	PROPN
bjp-23039	368	26	(	(	PUNCT
bjp-23039	368	27	principal	principal	ADJ
bjp-23039	368	28	contact	contact	NOUN
bjp-23039	368	29	)	)	PUNCT
bjp-23039	368	30	e	e	NOUN
bjp-23039	368	31	-	-	NOUN
bjp-23039	368	32	mail	mail	NOUN
bjp-23039	368	33	:	:	PUNCT
bjp-23039	368	34	ljm63630@gmail.com	ljm63630@gmail.com	NOUN
bjp-23039	368	35	;	;	PUNCT
bjp-23039	368	36	tel	tel	PROPN
bjp-23039	368	37	&	&	CCONJ
bjp-23039	368	38	fax	fax	PROPN
bjp-23039	368	39	:	:	PUNCT
bjp-23039	368	40	008637963546521	008637963546521	NUM
bjp-23039	368	41	li	li	PROPN
bjp-23039	368	42	hy	hy	PROPN
bjp-23039	368	43	,	,	PUNCT
bjp-23039	368	44	zhang	zhang	PROPN
bjp-23039	368	45	j	j	PROPN
bjp-23039	368	46	sun	sun	PROPN
bjp-23039	368	47	ll	ll	PROPN
bjp-23039	368	48	,	,	PUNCT
bjp-23039	368	49	li	li	PROPN
bjp-23039	368	50	bh	bh	PROPN
bjp-23039	368	51	,	,	PUNCT
bjp-23039	368	52	gao	gao	PROPN
bjp-23039	368	53	hl	hl	PROPN
bjp-23039	368	54	,	,	PUNCT
bjp-23039	368	55	xie	xie	PROPN
bjp-23039	368	56	t	t	PROPN
bjp-23039	368	57	,	,	PUNCT
bjp-23039	368	58	zhang	zhang	PROPN
bjp-23039	368	59	n	n	CCONJ
bjp-23039	368	60	,	,	PUNCT
bjp-23039	368	61	ye	ye	PROPN
bjp-23039	368	62	zm	zm	PROPN
bjp-23039	368	63	.	.	PUNCT
bjp-23039	369	1	celastrol	celastrol	NOUN
bjp-23039	369	2	induces	induce	VERB
bjp-23039	369	3	apoptosis	apoptosis	NOUN
bjp-23039	369	4	and	and	CCONJ
bjp-23039	369	5	autophagy	autophagy	VERB
bjp-23039	369	6	via	via	ADP
bjp-23039	369	7	the	the	DET
bjp-23039	369	8	ros	ros	PROPN
bjp-23039	369	9	/	/	SYM
bjp-23039	369	10	jnk	jnk	PROPN
bjp-23039	369	11	signaling	signal	VERB
bjp-23039	369	12	pathway	pathway	NOUN
bjp-23039	369	13	in	in	ADP
bjp-23039	369	14	human	human	ADJ
bjp-23039	369	15	osteosarcomacells	osteosarcomacell	NOUN
bjp-23039	369	16	:	:	PUNCT
bjp-23039	369	17	an	an	DET
bjp-23039	369	18	in	in	ADP
bjp-23039	369	19	vitro	vitro	X
bjp-23039	369	20	and	and	CCONJ
bjp-23039	369	21	in	in	ADP
bjp-23039	369	22	vivo	vivo	NOUN
bjp-23039	369	23	study	study	NOUN
bjp-23039	369	24	.	.	PUNCT
bjp-23039	370	1	cell	cell	NOUN
bjp-23039	370	2	death	death	NOUN
bjp-23039	370	3	dis	dis	PROPN
bjp-23039	370	4	.	.	PUNCT
bjp-23039	371	1	2015	2015	NUM
bjp-23039	371	2	;	;	PUNCT
bjp-23039	371	3	6	6	NUM
bjp-23039	371	4	:	:	PUNCT
bjp-23039	371	5	e1604	e1604	PROPN
bjp-23039	371	6	lin	lin	PROPN
bjp-23039	371	7	cc	cc	PROPN
bjp-23039	371	8	,	,	PUNCT
bjp-23039	371	9	kuo	kuo	PROPN
bjp-23039	371	10	cl	cl	PROPN
bjp-23039	371	11	,	,	PUNCT
bjp-23039	371	12	lee	lee	PROPN
bjp-23039	371	13	mh	mh	PROPN
bjp-23039	371	14	,	,	PUNCT
bjp-23039	371	15	lai	lai	PROPN
bjp-23039	371	16	kc	kc	PROPN
bjp-23039	371	17	,	,	PUNCT
bjp-23039	371	18	lin	lin	PROPN
bjp-23039	371	19	jp	jp	PROPN
bjp-23039	371	20	,	,	PUNCT
bjp-23039	371	21	yang	yang	PROPN
bjp-23039	371	22	js	js	PROPN
bjp-23039	371	23	,	,	PUNCT
bjp-23039	371	24	yu	yu	PROPN
bjp-23039	371	25	cs	cs	PROPN
bjp-23039	371	26	,	,	PUNCT
bjp-23039	371	27	lu	lu	PROPN
bjp-23039	371	28	cc	cc	PROPN
bjp-23039	371	29	,	,	PUNCT
bjp-23039	371	30	chiang	chiang	PROPN
bjp-23039	371	31	jh	jh	PROPN
bjp-23039	371	32	,	,	PUNCT
bjp-23039	371	33	chueh	chueh	PROPN
bjp-23039	371	34	fs	fs	PROPN
bjp-23039	371	35	,	,	PUNCT
bjp-23039	371	36	chung	chung	PROPN
bjp-23039	371	37	jg	jg	PROPN
bjp-23039	371	38	.	.	PROPN
bjp-23039	372	1	wogonin	wogonin	PROPN
bjp-23039	372	2	triggers	trigger	NOUN
bjp-23039	372	3	apoptosis	apoptosis	NOUN
bjp-23039	372	4	in	in	ADP
bjp-23039	372	5	human	human	ADJ
bjp-23039	372	6	osteosarcoma	osteosarcoma	ADJ
bjp-23039	372	7	u-2	u-2	PROPN
bjp-23039	372	8	os	os	PROPN
bjp-23039	372	9	cells	cell	NOUN
bjp-23039	372	10	through	through	ADP
bjp-23039	372	11	the	the	DET
bjp-23039	372	12	endoplasmic	endoplasmic	ADJ
bjp-23039	372	13	reticulum	reticulum	NOUN
bjp-23039	372	14	stress	stress	NOUN
bjp-23039	372	15	,	,	PUNCT
bjp-23039	372	16	mitochondrial	mitochondrial	ADJ
bjp-23039	372	17	dysfunction	dysfunction	NOUN
bjp-23039	372	18	and	and	CCONJ
bjp-23039	372	19	caspase-3	caspase-3	NOUN
bjp-23039	372	20	-	-	ADJ
bjp-23039	372	21	dependent	dependent	ADJ
bjp-23039	372	22	signalling	signal	VERB
bjp-23039	372	23	pathways	pathway	NOUN
bjp-23039	372	24	.	.	PUNCT
bjp-23039	373	1	int	int	NOUN
bjp-23039	373	2	j	j	PROPN
bjp-23039	373	3	oncol	oncol	ADJ
bjp-23039	373	4	.	.	PUNCT
bjp-23039	374	1	2011	2011	NUM
bjp-23039	374	2	;	;	PUNCT
bjp-23039	374	3	39	39	NUM
bjp-23039	374	4	:	:	PUNCT
bjp-23039	374	5	217	217	NUM
bjp-23039	374	6	-	-	SYM
bjp-23039	374	7	24	24	NUM
bjp-23039	374	8	.	.	PUNCT
bjp-23039	375	1	lu	lu	PROPN
bjp-23039	375	2	x	x	PROPN
bjp-23039	375	3	,	,	PUNCT
bjp-23039	375	4	jung	jung	PROPN
bjp-23039	375	5	j	j	PROPN
bjp-23039	375	6	,	,	PUNCT
bjp-23039	375	7	cho	cho	PROPN
bjp-23039	375	8	hj	hj	PROPN
bjp-23039	375	9	,	,	PUNCT
bjp-23039	375	10	lim	lim	PROPN
bjp-23039	375	11	dy	dy	PROPN
bjp-23039	375	12	,	,	PUNCT
bjp-23039	375	13	lee	lee	PROPN
bjp-23039	375	14	hs	hs	PROPN
bjp-23039	375	15	,	,	PUNCT
bjp-23039	375	16	chun	chun	PROPN
bjp-23039	375	17	hs	hs	PROPN
bjp-23039	375	18	,	,	PUNCT
bjp-23039	375	19	kwon	kwon	PROPN
bjp-23039	375	20	dy	dy	X
bjp-23039	375	21	,	,	PUNCT
bjp-23039	375	22	park	park	PROPN
bjp-23039	375	23	jh	jh	PROPN
bjp-23039	375	24	.	.	PROPN
bjp-23039	375	25	fisetin	fisetin	PROPN
bjp-23039	375	26	inhibits	inhibit	VERB
bjp-23039	375	27	the	the	DET
bjp-23039	375	28	activities	activity	NOUN
bjp-23039	375	29	of	of	ADP
bjp-23039	375	30	cyclin	cyclin	NOUN
bjp-23039	375	31	-	-	PUNCT
bjp-23039	375	32	dependent	dependent	ADJ
bjp-23039	375	33	kinases	kinase	NOUN
bjp-23039	375	34	leading	lead	VERB
bjp-23039	375	35	to	to	ADP
bjp-23039	375	36	cell	cell	NOUN
bjp-23039	375	37	cycle	cycle	NOUN
bjp-23039	375	38	arrest	arrest	NOUN
bjp-23039	375	39	in	in	ADP
bjp-23039	375	40	ht-29	ht-29	PUNCT
bjp-23039	375	41	human	human	ADJ
bjp-23039	375	42	colon	colon	NOUN
bjp-23039	375	43	cancer	cancer	NOUN
bjp-23039	375	44	cells	cell	NOUN
bjp-23039	375	45	.	.	PUNCT
bjp-23039	376	1	j	j	PROPN
bjp-23039	376	2	nutr	nutr	PROPN
bjp-23039	376	3	.	.	PROPN
bjp-23039	376	4	2005b	2005b	NUM
bjp-23039	376	5	;	;	PUNCT
bjp-23039	376	6	135	135	NUM
bjp-23039	376	7	:	:	SYM
bjp-23039	376	8	2884	2884	NUM
bjp-23039	376	9	-	-	SYM
bjp-23039	376	10	90	90	NUM
bjp-23039	376	11	.	.	PUNCT
bjp-23039	377	1	luetke	luetke	PROPN
bjp-23039	377	2	a	a	PRON
bjp-23039	377	3	,	,	PUNCT
bjp-23039	377	4	meyers	meyers	PROPN
bjp-23039	377	5	pa	pa	PROPN
bjp-23039	377	6	,	,	PUNCT
bjp-23039	377	7	lewis	lewis	PROPN
bjp-23039	377	8	i	i	PROPN
bjp-23039	377	9	,	,	PUNCT
bjp-23039	377	10	juergens	juergen	VERB
bjp-23039	377	11	h.	h.	PROPN
bjp-23039	377	12	osteosarcoma	osteosarcoma	ADJ
bjp-23039	377	13	treatment	treatment	NOUN
bjp-23039	377	14	:	:	PUNCT
bjp-23039	377	15	where	where	SCONJ
bjp-23039	377	16	do	do	AUX
bjp-23039	377	17	we	we	PRON
bjp-23039	377	18	stand	stand	VERB
bjp-23039	377	19	?	?	PUNCT
bjp-23039	378	1	a	a	DET
bjp-23039	378	2	state	state	NOUN
bjp-23039	378	3	of	of	ADP
bjp-23039	378	4	the	the	DET
bjp-23039	378	5	art	art	NOUN
bjp-23039	378	6	review	review	NOUN
bjp-23039	378	7	.	.	PUNCT
bjp-23039	379	1	cancer	cancer	NOUN
bjp-23039	379	2	treat	treat	PROPN
bjp-23039	379	3	rev	rev	VERB
bjp-23039	379	4	.	.	PROPN
bjp-23039	379	5	2014	2014	NUM
bjp-23039	379	6	;	;	PUNCT
bjp-23039	379	7	40	40	NUM
bjp-23039	379	8	:	:	PUNCT
bjp-23039	379	9	523	523	NUM
bjp-23039	379	10	-	-	SYM
bjp-23039	379	11	32	32	NUM
bjp-23039	379	12	.	.	PUNCT
bjp-23039	380	1	nielsen	nielsen	PROPN
bjp-23039	380	2	-	-	PUNCT
bjp-23039	380	3	preiss	preiss	PROPN
bjp-23039	380	4	sm	sm	PROPN
bjp-23039	380	5	,	,	PUNCT
bjp-23039	380	6	silva	silva	PROPN
bjp-23039	380	7	sr	sr	PROPN
bjp-23039	380	8	,	,	PUNCT
bjp-23039	380	9	gillette	gillette	PROPN
bjp-23039	380	10	jm	jm	PROPN
bjp-23039	380	11	.	.	PROPN
bjp-23039	380	12	role	role	NOUN
bjp-23039	380	13	of	of	ADP
bjp-23039	380	14	pten	pten	NOUN
bjp-23039	380	15	and	and	CCONJ
bjp-23039	380	16	akt	akt	PROPN
bjp-23039	380	17	in	in	ADP
bjp-23039	380	18	the	the	DET
bjp-23039	380	19	regulation	regulation	NOUN
bjp-23039	380	20	of	of	ADP
bjp-23039	380	21	growth	growth	NOUN
bjp-23039	380	22	and	and	CCONJ
bjp-23039	380	23	apoptosis	apoptosis	NOUN
bjp-23039	380	24	in	in	ADP
bjp-23039	380	25	human	human	ADJ
bjp-23039	380	26	osteoblastic	osteoblastic	ADJ
bjp-23039	380	27	cells	cell	NOUN
bjp-23039	380	28	.	.	PUNCT
bjp-23039	381	1	j	j	PROPN
bjp-23039	381	2	cell	cell	PROPN
bjp-23039	381	3	biochem	biochem	PROPN
bjp-23039	381	4	.	.	PUNCT
bjp-23039	382	1	2003	2003	NUM
bjp-23039	382	2	;	;	PUNCT
bjp-23039	382	3	90	90	NUM
bjp-23039	382	4	:	:	PUNCT
bjp-23039	382	5	964	964	NUM
bjp-23039	382	6	-	-	SYM
bjp-23039	382	7	75	75	NUM
bjp-23039	382	8	.	.	PUNCT
bjp-23039	383	1	noh	noh	PROPN
bjp-23039	383	2	k	k	PROPN
bjp-23039	383	3	,	,	PUNCT
bjp-23039	383	4	kim	kim	PROPN
bjp-23039	383	5	ko	ko	PROPN
bjp-23039	383	6	,	,	PUNCT
bjp-23039	383	7	patel	patel	PROPN
bjp-23039	383	8	nr	nr	PROPN
bjp-23039	383	9	,	,	PUNCT
bjp-23039	383	10	staples	staples	PROPN
bjp-23039	383	11	jr	jr	PROPN
bjp-23039	383	12	,	,	PUNCT
bjp-23039	383	13	minematsu	minematsu	PROPN
bjp-23039	383	14	h	h	PROPN
bjp-23039	383	15	,	,	PUNCT
bjp-23039	383	16	nair	nair	PROPN
bjp-23039	383	17	k	k	PROPN
bjp-23039	383	18	,	,	PUNCT
bjp-23039	383	19	lee	lee	PROPN
bjp-23039	383	20	fy	fy	PROPN
bjp-23039	383	21	.	.	PUNCT
bjp-23039	383	22	targeting	target	VERB
bjp-23039	383	23	inflammatory	inflammatory	ADJ
bjp-23039	383	24	kinase	kinase	NOUN
bjp-23039	383	25	as	as	ADP
bjp-23039	383	26	an	an	DET
bjp-23039	383	27	adjuvant	adjuvant	ADJ
bjp-23039	383	28	treatment	treatment	NOUN
bjp-23039	383	29	for	for	ADP
bjp-23039	383	30	osteosarcomas	osteosarcomas	NOUN
bjp-23039	383	31	.	.	PUNCT
bjp-23039	384	1	j	j	PROPN
bjp-23039	384	2	bone	bone	PROPN
bjp-23039	384	3	joint	joint	ADJ
bjp-23039	384	4	surg	surg	NOUN
bjp-23039	384	5	am	be	AUX
bjp-23039	384	6	.	.	PUNCT
bjp-23039	385	1	2011	2011	NUM
bjp-23039	385	2	;	;	PUNCT
bjp-23039	385	3	93	93	NUM
bjp-23039	385	4	:	:	PUNCT
bjp-23039	385	5	723	723	NUM
bjp-23039	385	6	-	-	SYM
bjp-23039	385	7	32	32	NUM
bjp-23039	385	8	.	.	PUNCT
bjp-23039	386	1	obata	obata	PROPN
bjp-23039	386	2	t	t	PROPN
bjp-23039	386	3	,	,	PUNCT
bjp-23039	386	4	brown	brown	PROPN
bjp-23039	386	5	ge	ge	PROPN
bjp-23039	386	6	,	,	PUNCT
bjp-23039	386	7	yaffe	yaffe	PROPN
bjp-23039	386	8	mb	mb	NOUN
bjp-23039	386	9	.	.	PROPN
bjp-23039	386	10	map	map	PROPN
bjp-23039	386	11	kinase	kinase	PROPN
bjp-23039	386	12	pathways	pathway	NOUN
bjp-23039	386	13	activated	activate	VERB
bjp-23039	386	14	by	by	ADP
bjp-23039	386	15	stress	stress	NOUN
bjp-23039	386	16	:	:	PUNCT
bjp-23039	386	17	the	the	DET
bjp-23039	386	18	p38	p38	ADJ
bjp-23039	386	19	mapk	mapk	NOUN
bjp-23039	386	20	pathway	pathway	NOUN
bjp-23039	386	21	.	.	PUNCT
bjp-23039	387	1	crit	crit	PROPN
bjp-23039	387	2	care	care	PROPN
bjp-23039	387	3	med	med	PROPN
bjp-23039	387	4	.	.	PUNCT
bjp-23039	387	5	2000	2000	NUM
bjp-23039	387	6	;	;	PUNCT
bjp-23039	387	7	28	28	NUM
bjp-23039	387	8	:	:	PUNCT
bjp-23039	387	9	n67	n67	NOUN
bjp-23039	387	10	-	-	PUNCT
bjp-23039	387	11	n77	n77	PROPN
bjp-23039	387	12	.	.	PUNCT
bjp-23039	388	1	park	park	PROPN
bjp-23039	388	2	wh	wh	PROPN
bjp-23039	388	3	.	.	PUNCT
bjp-23039	389	1	mapk	mapk	NOUN
bjp-23039	389	2	inhibitors	inhibitor	NOUN
bjp-23039	389	3	differentially	differentially	ADV
bjp-23039	389	4	affect	affect	VERB
bjp-23039	389	5	gallic	gallic	NOUN
bjp-23039	389	6	acid	acid	PROPN
bjp-23039	389	7	induced	induce	VERB
bjp-23039	389	8	human	human	ADJ
bjp-23039	389	9	pulmonary	pulmonary	ADJ
bjp-23039	389	10	fibroblast	fibroblast	ADJ
bjp-23039	389	11	cell	cell	NOUN
bjp-23039	389	12	growth	growth	NOUN
bjp-23039	389	13	inhibition	inhibition	NOUN
bjp-23039	389	14	.	.	PUNCT
bjp-23039	390	1	mol	mol	ADP
bjp-23039	390	2	med	med	ADJ
bjp-23039	390	3	report	report	NOUN
bjp-23039	390	4	.	.	PUNCT
bjp-23039	391	1	2011	2011	NUM
bjp-23039	391	2	;	;	PUNCT
bjp-23039	391	3	4	4	NUM
bjp-23039	391	4	:	:	SYM
bjp-23039	391	5	193	193	NUM
bjp-23039	391	6	-	-	SYM
bjp-23039	391	7	204	204	NUM
bjp-23039	391	8	.	.	PUNCT
bjp-23039	392	1	pelicano	pelicano	PROPN
bjp-23039	392	2	h	h	PROPN
bjp-23039	392	3	,	,	PUNCT
bjp-23039	392	4	carney	carney	PROPN
bjp-23039	392	5	d	d	PROPN
bjp-23039	392	6	,	,	PUNCT
bjp-23039	392	7	huang	huang	PROPN
bjp-23039	392	8	p.	p.	PROPN
bjp-23039	392	9	ros	ros	PROPN
bjp-23039	392	10	stress	stress	NOUN
bjp-23039	392	11	in	in	ADP
bjp-23039	392	12	cancer	cancer	NOUN
bjp-23039	392	13	cells	cell	NOUN
bjp-23039	392	14	and	and	CCONJ
bjp-23039	392	15	therapeutic	therapeutic	ADJ
bjp-23039	392	16	implications	implication	NOUN
bjp-23039	392	17	.	.	PUNCT
bjp-23039	393	1	drug	drug	NOUN
bjp-23039	393	2	resist	resist	NOUN
bjp-23039	393	3	update	update	NOUN
bjp-23039	393	4	.	.	PUNCT
bjp-23039	394	1	2004	2004	NUM
bjp-23039	394	2	;	;	PUNCT
bjp-23039	394	3	7	7	NUM
bjp-23039	394	4	:	:	SYM
bjp-23039	394	5	97110	97110	NUM
bjp-23039	394	6	.	.	PUNCT
bjp-23039	395	1	porta	porta	PROPN
bjp-23039	395	2	c	c	X
bjp-23039	395	3	,	,	PUNCT
bjp-23039	395	4	paglino	paglino	PROPN
bjp-23039	395	5	c	c	X
bjp-23039	395	6	,	,	PUNCT
bjp-23039	395	7	mosca	mosca	PROPN
bjp-23039	395	8	a.	a.	NOUN
bjp-23039	395	9	targeting	target	VERB
bjp-23039	395	10	pi3k	pi3k	PROPN
bjp-23039	395	11	/	/	SYM
bjp-23039	395	12	akt	akt	PROPN
bjp-23039	395	13	/	/	SYM
bjp-23039	395	14	mtor	mtor	PROPN
bjp-23039	395	15	signaling	signal	VERB
bjp-23039	395	16	in	in	ADP
bjp-23039	395	17	cancer	cancer	NOUN
bjp-23039	395	18	.	.	PUNCT
bjp-23039	396	1	front	front	ADJ
bjp-23039	396	2	oncol	oncol	ADJ
bjp-23039	396	3	.	.	PUNCT
bjp-23039	397	1	2014	2014	NUM
bjp-23039	397	2	;	;	PUNCT
bjp-23039	397	3	4	4	NUM
bjp-23039	397	4	:	:	SYM
bjp-23039	397	5	64	64	NUM
bjp-23039	397	6	.	.	PUNCT
bjp-23039	398	1	qi	qi	PROPN
bjp-23039	398	2	f	f	PROPN
bjp-23039	398	3	,	,	PUNCT
bjp-23039	398	4	li	li	PROPN
bjp-23039	398	5	a	a	PROPN
bjp-23039	398	6	,	,	PUNCT
bjp-23039	398	7	zhao	zhao	PROPN
bjp-23039	398	8	l	l	PROPN
bjp-23039	398	9	,	,	PUNCT
bjp-23039	398	10	xu	xu	PROPN
bjp-23039	398	11	h	h	PROPN
bjp-23039	398	12	,	,	PUNCT
bjp-23039	398	13	inagaki	inagaki	PROPN
bjp-23039	398	14	y	y	PROPN
bjp-23039	398	15	,	,	PUNCT
bjp-23039	398	16	wang	wang	PROPN
bjp-23039	398	17	d	d	PROPN
bjp-23039	398	18	,	,	PUNCT
bjp-23039	398	19	cui	cui	NOUN
bjp-23039	398	20	x	x	NOUN
bjp-23039	398	21	,	,	PUNCT
bjp-23039	398	22	gao	gao	PROPN
bjp-23039	398	23	b	b	PROPN
bjp-23039	398	24	,	,	PUNCT
bjp-23039	398	25	kokudo	kokudo	PROPN
bjp-23039	398	26	n	n	CCONJ
bjp-23039	398	27	,	,	PUNCT
bjp-23039	398	28	nakata	nakata	PROPN
bjp-23039	398	29	m	m	PROPN
bjp-23039	398	30	,	,	PUNCT
bjp-23039	398	31	tang	tang	PROPN
bjp-23039	398	32	w.	w.	PROPN
bjp-23039	398	33	cinobufacini	cinobufacini	PROPN
bjp-23039	398	34	,	,	PUNCT
bjp-23039	398	35	an	an	DET
bjp-23039	398	36	aqueous	aqueous	ADJ
bjp-23039	398	37	extract	extract	NOUN
bjp-23039	398	38	from	from	ADP
bjp-23039	398	39	bufo	bufo	PROPN
bjp-23039	398	40	bufo	bufo	PROPN
bjp-23039	398	41	gargarizans	gargarizans	PROPN
bjp-23039	398	42	cantor	cantor	PROPN
bjp-23039	398	43	,	,	PUNCT
bjp-23039	398	44	induces	induce	VERB
bjp-23039	398	45	apoptosis	apoptosis	NOUN
bjp-23039	398	46	through	through	ADP
bjp-23039	398	47	a	a	DET
bjp-23039	398	48	mitochondria	mitochondria	NOUN
bjp-23039	398	49	-	-	PUNCT
bjp-23039	398	50	mediated	mediate	VERB
bjp-23039	398	51	pathway	pathway	NOUN
bjp-23039	398	52	in	in	ADP
bjp-23039	398	53	human	human	ADJ
bjp-23039	398	54	hepatocellular	hepatocellular	ADJ
bjp-23039	398	55	carcinoma	carcinoma	NOUN
bjp-23039	398	56	cells	cell	NOUN
bjp-23039	398	57	.	.	PUNCT
bjp-23039	399	1	j	j	PROPN
bjp-23039	399	2	ethnopharmacol	ethnopharmacol	PROPN
bjp-23039	399	3	.	.	PUNCT
bjp-23039	400	1	2010	2010	NUM
bjp-23039	400	2	;	;	PUNCT
bjp-23039	400	3	128	128	NUM
bjp-23039	400	4	:	:	SYM
bjp-23039	400	5	654	654	NUM
bjp-23039	400	6	-	-	SYM
bjp-23039	400	7	61	61	NUM
bjp-23039	400	8	.	.	PUNCT
bjp-23039	401	1	raza	raza	PROPN
bjp-23039	401	2	h	h	PROPN
bjp-23039	401	3	,	,	PUNCT
bjp-23039	401	4	john	john	PROPN
bjp-23039	401	5	a	a	PROPN
bjp-23039	401	6	,	,	PUNCT
bjp-23039	401	7	benedict	benedict	PROPN
bjp-23039	401	8	s.	s.	PROPN
bjp-23039	401	9	acetylsalicylic	acetylsalicylic	PROPN
bjp-23039	401	10	acid	acid	NOUN
bjp-23039	401	11	-	-	PUNCT
bjp-23039	401	12	induced	induce	VERB
bjp-23039	401	13	oxidative	oxidative	ADJ
bjp-23039	401	14	stress	stress	NOUN
bjp-23039	401	15	,	,	PUNCT
bjp-23039	401	16	cell	cell	NOUN
bjp-23039	401	17	cycle	cycle	NOUN
bjp-23039	401	18	arrest	arrest	NOUN
bjp-23039	401	19	,	,	PUNCT
bjp-23039	401	20	apoptosis	apoptosis	NOUN
bjp-23039	401	21	and	and	CCONJ
bjp-23039	401	22	mitochondrial	mitochondrial	ADJ
bjp-23039	401	23	dysfunction	dysfunction	NOUN
bjp-23039	401	24	in	in	ADP
bjp-23039	401	25	human	human	ADJ
bjp-23039	401	26	hepatoma	hepatoma	NOUN
bjp-23039	401	27	hepg2	hepg2	PUNCT
bjp-23039	401	28	cells	cell	NOUN
bjp-23039	401	29	.	.	PUNCT
bjp-23039	402	1	eur	eur	PROPN
bjp-23039	402	2	j	j	PROPN
bjp-23039	402	3	pharmacol	pharmacol	PROPN
bjp-23039	402	4	.	.	PUNCT
bjp-23039	402	5	2011	2011	NUM
bjp-23039	402	6	;	;	PUNCT
bjp-23039	402	7	668	668	NUM
bjp-23039	402	8	:	:	PUNCT
bjp-23039	402	9	15	15	NUM
bjp-23039	402	10	-	-	SYM
bjp-23039	402	11	24	24	NUM
bjp-23039	402	12	.	.	PUNCT
bjp-23039	402	13	seki	seki	PROPN
bjp-23039	402	14	e	e	PROPN
bjp-23039	402	15	,	,	PUNCT
bjp-23039	402	16	brenner	brenner	PROPN
bjp-23039	402	17	da	da	PROPN
bjp-23039	402	18	,	,	PUNCT
bjp-23039	402	19	karin	karin	PROPN
bjp-23039	402	20	m.	m.	NOUN
bjp-23039	402	21	a	a	DET
bjp-23039	402	22	liver	liver	NOUN
bjp-23039	402	23	full	full	ADJ
bjp-23039	402	24	of	of	ADP
bjp-23039	402	25	jnk	jnk	PROPN
bjp-23039	402	26	:	:	PUNCT
bjp-23039	402	27	signalling	signal	VERB
bjp-23039	402	28	in	in	ADP
bjp-23039	402	29	regulation	regulation	NOUN
bjp-23039	402	30	of	of	ADP
bjp-23039	402	31	cell	cell	NOUN
bjp-23039	402	32	function	function	NOUN
bjp-23039	402	33	and	and	CCONJ
bjp-23039	402	34	disease	disease	NOUN
bjp-23039	402	35	pathogenesis	pathogenesis	NOUN
bjp-23039	402	36	,	,	PUNCT
bjp-23039	402	37	and	and	CCONJ
bjp-23039	402	38	clinical	clinical	ADJ
bjp-23039	402	39	approaches	approach	NOUN
bjp-23039	402	40	.	.	PUNCT
bjp-23039	403	1	gastroenterology	gastroenterology	NOUN
bjp-23039	403	2	2012	2012	NUM
bjp-23039	403	3	;	;	PUNCT
bjp-23039	403	4	143	143	NUM
bjp-23039	403	5	:	:	PUNCT
bjp-23039	403	6	307	307	NUM
bjp-23039	403	7	-	-	SYM
bjp-23039	403	8	20	20	NUM
bjp-23039	403	9	shen	shen	NOUN
bjp-23039	403	10	hm	hm	INTJ
bjp-23039	403	11	,	,	PUNCT
bjp-23039	403	12	liu	liu	PROPN
bjp-23039	403	13	zg	zg	PROPN
bjp-23039	403	14	.	.	PROPN
bjp-23039	404	1	jnk	jnk	PROPN
bjp-23039	404	2	signaling	signal	VERB
bjp-23039	404	3	pathway	pathway	NOUN
bjp-23039	404	4	is	be	AUX
bjp-23039	404	5	a	a	DET
bjp-23039	404	6	key	key	ADJ
bjp-23039	404	7	modulator	modulator	NOUN
bjp-23039	404	8	in	in	ADP
bjp-23039	404	9	cell	cell	NOUN
bjp-23039	404	10	death	death	NOUN
bjp-23039	404	11	mediated	mediate	VERB
bjp-23039	404	12	by	by	ADP
bjp-23039	404	13	reactive	reactive	ADJ
bjp-23039	404	14	oxygen	oxygen	NOUN
bjp-23039	404	15	and	and	CCONJ
bjp-23039	404	16	nitrogen	nitrogen	NOUN
bjp-23039	404	17	species	specie	NOUN
bjp-23039	404	18	.	.	PUNCT
bjp-23039	405	1	free	free	ADJ
bjp-23039	405	2	radical	radical	ADJ
bjp-23039	405	3	biol	biol	NOUN
bjp-23039	405	4	med	me	VERB
bjp-23039	405	5	.	.	PUNCT
bjp-23039	406	1	2006	2006	NUM
bjp-23039	406	2	;	;	PUNCT
bjp-23039	406	3	40	40	NUM
bjp-23039	406	4	:	:	PUNCT
bjp-23039	406	5	928	928	NUM
bjp-23039	406	6	-	-	SYM
bjp-23039	406	7	39	39	NUM
bjp-23039	406	8	.	.	PUNCT
bjp-23039	407	1	simon	simon	PROPN
bjp-23039	407	2	hu	hu	PROPN
bjp-23039	407	3	,	,	PUNCT
bjp-23039	407	4	haj	haj	PROPN
bjp-23039	407	5	-	-	PROPN
bjp-23039	407	6	yehia	yehia	NOUN
bjp-23039	407	7	a	a	X
bjp-23039	407	8	,	,	PUNCT
bjp-23039	407	9	levi	levi	PROPN
bjp-23039	407	10	-	-	PUNCT
bjp-23039	407	11	schaffer	schaffer	PROPN
bjp-23039	407	12	f.	f.	PROPN
bjp-23039	407	13	role	role	NOUN
bjp-23039	407	14	of	of	ADP
bjp-23039	407	15	reactive	reactive	ADJ
bjp-23039	407	16	oxygen	oxygen	NOUN
bjp-23039	407	17	species	specie	NOUN
bjp-23039	407	18	(	(	PUNCT
bjp-23039	407	19	ros	ros	PROPN
bjp-23039	407	20	)	)	PUNCT
bjp-23039	407	21	in	in	ADP
bjp-23039	407	22	apoptosis	apoptosis	NOUN
bjp-23039	407	23	induction	induction	NOUN
bjp-23039	407	24	.	.	PUNCT
bjp-23039	408	1	apoptosis	apoptosis	NOUN
bjp-23039	408	2	2000	2000	NUM
bjp-23039	408	3	;	;	PUNCT
bjp-23039	408	4	5	5	NUM
bjp-23039	408	5	:	:	SYM
bjp-23039	408	6	415	415	NUM
bjp-23039	408	7	-	-	SYM
bjp-23039	408	8	18	18	NUM
bjp-23039	408	9	.	.	PUNCT
bjp-23039	409	1	tournier	tournier	PROPN
bjp-23039	409	2	c	c	NOUN
bjp-23039	409	3	,	,	PUNCT
bjp-23039	409	4	hess	hess	PROPN
bjp-23039	409	5	p	p	NOUN
bjp-23039	409	6	,	,	PUNCT
bjp-23039	409	7	yang	yang	PROPN
bjp-23039	409	8	dd	dd	PROPN
bjp-23039	409	9	,	,	PUNCT
bjp-23039	409	10	xu	xu	PROPN
bjp-23039	409	11	j	j	PROPN
bjp-23039	409	12	,	,	PUNCT
bjp-23039	409	13	turner	turner	PROPN
bjp-23039	409	14	tk	tk	PROPN
bjp-23039	409	15	,	,	PUNCT
bjp-23039	409	16	nimnual	nimnual	ADV
bjp-23039	409	17	a	a	PRON
bjp-23039	409	18	,	,	PUNCT
bjp-23039	409	19	bar	bar	NOUN
bjp-23039	409	20	-	-	PUNCT
bjp-23039	409	21	sagi	sagi	NOUN
bjp-23039	409	22	d	d	PROPN
bjp-23039	409	23	,	,	PUNCT
bjp-23039	409	24	jones	jones	PROPN
bjp-23039	409	25	sn	sn	PROPN
bjp-23039	409	26	,	,	PUNCT
bjp-23039	409	27	flavell	flavell	PROPN
bjp-23039	409	28	ra	ra	PROPN
bjp-23039	409	29	,	,	PUNCT
bjp-23039	409	30	davis	davis	PROPN
bjp-23039	409	31	rj	rj	PROPN
bjp-23039	409	32	.	.	PROPN
bjp-23039	409	33	requirement	requirement	NOUN
bjp-23039	409	34	of	of	ADP
bjp-23039	409	35	jnk	jnk	PROPN
bjp-23039	409	36	for	for	ADP
bjp-23039	409	37	stress	stress	NOUN
bjp-23039	409	38	-	-	PUNCT
bjp-23039	409	39	induced	induce	VERB
bjp-23039	409	40	activation	activation	NOUN
bjp-23039	409	41	of	of	ADP
bjp-23039	409	42	the	the	DET
bjp-23039	409	43	cytochrome	cytochrome	NOUN
bjp-23039	409	44	cmediated	cmediated	ADJ
bjp-23039	409	45	death	death	NOUN
bjp-23039	409	46	pathway	pathway	NOUN
bjp-23039	409	47	.	.	PUNCT
bjp-23039	410	1	science	science	NOUN
bjp-23039	410	2	2000	2000	NUM
bjp-23039	410	3	;	;	PUNCT
bjp-23039	410	4	288	288	NUM
bjp-23039	410	5	:	:	PUNCT
bjp-23039	410	6	870	870	NUM
bjp-23039	410	7	-	-	SYM
bjp-23039	410	8	74	74	NUM
bjp-23039	410	9	.	.	PUNCT
bjp-23039	411	1	trachootham	trachootham	NOUN
bjp-23039	411	2	d	d	PROPN
bjp-23039	411	3	,	,	PUNCT
bjp-23039	411	4	alexandre	alexandre	PROPN
bjp-23039	411	5	j	j	PROPN
bjp-23039	411	6	,	,	PUNCT
bjp-23039	411	7	huang	huang	PROPN
bjp-23039	411	8	p.	p.	PROPN
bjp-23039	411	9	targeting	target	VERB
bjp-23039	411	10	cancer	cancer	NOUN
bjp-23039	411	11	cells	cell	NOUN
bjp-23039	411	12	by	by	ADP
bjp-23039	411	13	ros	ros	PROPN
bjp-23039	411	14	-	-	PUNCT
bjp-23039	411	15	mediated	mediate	VERB
bjp-23039	411	16	mechanisms	mechanism	NOUN
bjp-23039	411	17	:	:	PUNCT
bjp-23039	411	18	a	a	DET
bjp-23039	411	19	radical	radical	ADJ
bjp-23039	411	20	therapeutic	therapeutic	ADJ
bjp-23039	411	21	approach	approach	NOUN
bjp-23039	411	22	?	?	PUNCT
bjp-23039	412	1	nat	nat	PROPN
bjp-23039	412	2	rev	rev	VERB
bjp-23039	412	3	drug	drug	NOUN
bjp-23039	412	4	discov	discov	NOUN
bjp-23039	412	5	.	.	PUNCT
bjp-23039	413	1	2009	2009	NUM
bjp-23039	413	2	;	;	PUNCT
bjp-23039	413	3	8	8	NUM
bjp-23039	413	4	:	:	SYM
bjp-23039	413	5	579	579	NUM
bjp-23039	413	6	-	-	SYM
bjp-23039	413	7	91	91	NUM
bjp-23039	413	8	.	.	PUNCT
bjp-23039	414	1	vanloo	vanloo	PROPN
bjp-23039	414	2	g	g	NOUN
bjp-23039	414	3	,	,	PUNCT
bjp-23039	414	4	saelens	saelen	NOUN
bjp-23039	414	5	x	x	NOUN
bjp-23039	414	6	,	,	PUNCT
bjp-23039	414	7	van	van	PROPN
bjp-23039	414	8	gurp	gurp	NOUN
bjp-23039	414	9	m	m	PROPN
bjp-23039	414	10	,	,	PUNCT
bjp-23039	414	11	macfarlane	macfarlane	PROPN
bjp-23039	414	12	m	m	PROPN
bjp-23039	414	13	,	,	PUNCT
bjp-23039	414	14	martin	martin	PROPN
bjp-23039	414	15	sj	sj	PROPN
bjp-23039	414	16	,	,	PUNCT
bjp-23039	414	17	vandenabeele	vandenabeele	PROPN
bjp-23039	414	18	p.	p.	NOUN
bjp-23039	414	19	the	the	DET
bjp-23039	414	20	role	role	NOUN
bjp-23039	414	21	of	of	ADP
bjp-23039	414	22	mitochondrial	mitochondrial	ADJ
bjp-23039	414	23	factors	factor	NOUN
bjp-23039	414	24	in	in	ADP
bjp-23039	414	25	apoptosis	apoptosis	NOUN
bjp-23039	414	26	:	:	PUNCT
bjp-23039	414	27	a	a	DET
bjp-23039	414	28	russian	russian	ADJ
bjp-23039	414	29	roulette	roulette	NOUN
bjp-23039	414	30	with	with	ADP
bjp-23039	414	31	more	more	ADJ
bjp-23039	414	32	than	than	ADP
bjp-23039	414	33	one	one	NUM
bjp-23039	414	34	bullet	bullet	NOUN
bjp-23039	414	35	.	.	PUNCT
bjp-23039	415	1	cell	cell	NOUN
bjp-23039	415	2	death	death	NOUN
bjp-23039	415	3	differ	differ	VERB
bjp-23039	415	4	.	.	PUNCT
bjp-23039	416	1	2002	2002	NUM
bjp-23039	416	2	;	;	PUNCT
bjp-23039	416	3	9	9	NUM
bjp-23039	416	4	:	:	SYM
bjp-23039	416	5	1031	1031	NUM
bjp-23039	416	6	-	-	SYM
bjp-23039	416	7	42	42	NUM
bjp-23039	416	8	.	.	PUNCT
bjp-23039	417	1	wagner	wagner	PROPN
bjp-23039	417	2	ef	ef	PROPN
bjp-23039	417	3	,	,	PUNCT
bjp-23039	417	4	nebreda	nebreda	PROPN
bjp-23039	417	5	ar	ar	PROPN
bjp-23039	417	6	.	.	PROPN
bjp-23039	417	7	signal	signal	PROPN
bjp-23039	417	8	integration	integration	NOUN
bjp-23039	417	9	by	by	ADP
bjp-23039	417	10	jnk	jnk	PROPN
bjp-23039	417	11	and	and	CCONJ
bjp-23039	417	12	p38	p38	PROPN
bjp-23039	417	13	mapk	mapk	NOUN
bjp-23039	417	14	pathways	pathway	NOUN
bjp-23039	417	15	in	in	ADP
bjp-23039	417	16	cancer	cancer	NOUN
bjp-23039	417	17	development	development	NOUN
bjp-23039	417	18	.	.	PUNCT
bjp-23039	418	1	nat	nat	PROPN
bjp-23039	418	2	rev	rev	VERB
bjp-23039	418	3	cancer	cancer	NOUN
bjp-23039	418	4	2009	2009	NUM
bjp-23039	418	5	;	;	PUNCT
bjp-23039	418	6	9	9	NUM
bjp-23039	418	7	:	:	SYM
bjp-23039	418	8	537	537	NUM
bjp-23039	418	9	-	-	SYM
bjp-23039	418	10	49	49	NUM
bjp-23039	418	11	.	.	PUNCT
bjp-23039	419	1	wang	wang	PROPN
bjp-23039	419	2	x	x	PROPN
bjp-23039	419	3	,	,	PUNCT
bjp-23039	419	4	martindale	martindale	PROPN
bjp-23039	419	5	jl	jl	PROPN
bjp-23039	419	6	,	,	PUNCT
bjp-23039	419	7	liu	liu	PROPN
bjp-23039	419	8	y	y	PROPN
bjp-23039	419	9	,	,	PUNCT
bjp-23039	419	10	holbrook	holbrook	PROPN
bjp-23039	419	11	nj	nj	PROPN
bjp-23039	419	12	.	.	PUNCT
bjp-23039	420	1	the	the	DET
bjp-23039	420	2	cellular	cellular	ADJ
bjp-23039	420	3	response	response	NOUN
bjp-23039	420	4	to	to	PART
bjp-23039	420	5	oxidative	oxidative	ADJ
bjp-23039	420	6	stress	stress	NOUN
bjp-23039	420	7	:	:	PUNCT
bjp-23039	420	8	influences	influence	NOUN
bjp-23039	420	9	of	of	ADP
bjp-23039	420	10	mitogen	mitogen	NOUN
bjp-23039	420	11	-	-	PUNCT
bjp-23039	420	12	activated	activate	VERB
bjp-23039	420	13	protein	protein	NOUN
bjp-23039	420	14	kinase	kinase	NOUN
bjp-23039	420	15	signalling	signal	VERB
bjp-23039	420	16	pathways	pathway	NOUN
bjp-23039	420	17	on	on	ADP
bjp-23039	420	18	cell	cell	NOUN
bjp-23039	420	19	survival	survival	NOUN
bjp-23039	420	20	.	.	PUNCT
bjp-23039	421	1	biochem	biochem	PROPN
bjp-23039	421	2	j.	j.	PROPN
bjp-23039	421	3	1998	1998	NUM
bjp-23039	421	4	;	;	PUNCT
bjp-23039	421	5	333	333	NUM
bjp-23039	421	6	:	:	PUNCT
bjp-23039	421	7	291	291	NUM
bjp-23039	421	8	-	-	SYM
bjp-23039	421	9	300	300	NUM
bjp-23039	421	10	.	.	PUNCT
bjp-23039	422	1	white	white	PROPN
bjp-23039	422	2	c	c	PROPN
bjp-23039	422	3	,	,	PUNCT
bjp-23039	422	4	li	li	PROPN
bjp-23039	422	5	c	c	PROPN
bjp-23039	422	6	,	,	PUNCT
bjp-23039	422	7	yang	yang	PROPN
bjp-23039	422	8	j	j	PROPN
bjp-23039	422	9	,	,	PUNCT
bjp-23039	422	10	petrenko	petrenko	PROPN
bjp-23039	422	11	nb	nb	PROPN
bjp-23039	422	12	,	,	PUNCT
bjp-23039	422	13	madesh	madesh	PROPN
bjp-23039	422	14	m	m	PROPN
bjp-23039	422	15	,	,	PUNCT
bjp-23039	422	16	thompson	thompson	PROPN
bjp-23039	422	17	cb	cb	PROPN
bjp-23039	422	18	,	,	PUNCT
bjp-23039	422	19	foskett	foskett	PROPN
bjp-23039	422	20	jk	jk	PROPN
bjp-23039	422	21	.	.	PUNCT
bjp-23039	423	1	the	the	DET
bjp-23039	423	2	endoplasmic	endoplasmic	ADJ
bjp-23039	423	3	reticulum	reticulum	NOUN
bjp-23039	423	4	gateway	gateway	NOUN
bjp-23039	423	5	to	to	PART
bjp-23039	423	6	apoptosis	apoptosis	VERB
bjp-23039	423	7	by	by	ADP
bjp-23039	423	8	bcl	bcl	PROPN
bjp-23039	423	9	-	-	PROPN
bjp-23039	423	10	xl	xl	PROPN
bjp-23039	423	11	modulation	modulation	NOUN
bjp-23039	423	12	of	of	ADP
bjp-23039	423	13	the	the	DET
bjp-23039	423	14	insp3r	insp3r	PROPN
bjp-23039	423	15	.	.	PUNCT
bjp-23039	424	1	nat	nat	PROPN
bjp-23039	424	2	cell	cell	NOUN
bjp-23039	424	3	biol	biol	PROPN
bjp-23039	424	4	.	.	PUNCT
bjp-23039	425	1	2005	2005	NUM
bjp-23039	425	2	;	;	PUNCT
bjp-23039	425	3	7	7	NUM
bjp-23039	425	4	:	:	SYM
bjp-23039	425	5	1021	1021	NUM
bjp-23039	425	6	-	-	SYM
bjp-23039	425	7	28	28	NUM
bjp-23039	425	8	.	.	PUNCT
bjp-23039	426	1	you	you	PRON
bjp-23039	426	2	br	br	PROPN
bjp-23039	426	3	,	,	PUNCT
bjp-23039	426	4	park	park	NOUN
bjp-23039	426	5	wh	wh	PROPN
bjp-23039	426	6	.	.	PUNCT
bjp-23039	427	1	the	the	DET
bjp-23039	427	2	effects	effect	NOUN
bjp-23039	427	3	of	of	ADP
bjp-23039	427	4	mitogen	mitogen	NOUN
bjp-23039	427	5	-	-	PUNCT
bjp-23039	427	6	activated	activate	VERB
bjp-23039	427	7	protein	protein	NOUN
bjp-23039	427	8	kinase	kinase	NOUN
bjp-23039	427	9	inhibitors	inhibitor	NOUN
bjp-23039	427	10	or	or	CCONJ
bjp-23039	427	11	small	small	ADJ
bjp-23039	427	12	interfering	interfere	VERB
bjp-23039	427	13	rnas	rna	NOUN
bjp-23039	427	14	on	on	ADP
bjp-23039	427	15	gallic	gallic	NOUN
bjp-23039	427	16	acid	acid	PROPN
bjp-23039	427	17	induced	induce	VERB
bjp-23039	427	18	hela	hela	PROPN
bjp-23039	427	19	cell	cell	NOUN
bjp-23039	427	20	death	death	NOUN
bjp-23039	427	21	in	in	ADP
bjp-23039	427	22	relation	relation	NOUN
bjp-23039	427	23	to	to	PART
bjp-23039	427	24	reactive	reactive	VERB
bjp-23039	427	25	oxygen	oxygen	NOUN
bjp-23039	427	26	species	specie	NOUN
bjp-23039	427	27	and	and	CCONJ
bjp-23039	427	28	glutathione	glutathione	NOUN
bjp-23039	427	29	.	.	PUNCT
bjp-23039	428	1	j	j	PROPN
bjp-23039	428	2	agric	agric	PROPN
bjp-23039	428	3	food	food	PROPN
bjp-23039	428	4	chem	chem	NOUN
bjp-23039	428	5	.	.	PUNCT
bjp-23039	429	1	2011	2011	NUM
bjp-23039	429	2	;	;	PUNCT
bjp-23039	429	3	59	59	NUM
bjp-23039	429	4	:	:	SYM
bjp-23039	429	5	76371	76371	NUM
bjp-23039	429	6	.	.	PUNCT
bjp-23039	430	1	yuan	yuan	PROPN
bjp-23039	430	2	tl	tl	PROPN
bjp-23039	430	3	,	,	PUNCT
bjp-23039	430	4	cantley	cantley	PROPN
bjp-23039	430	5	lc	lc	PROPN
bjp-23039	430	6	.	.	PUNCT
bjp-23039	431	1	pi3k	pi3k	NOUN
bjp-23039	431	2	pathway	pathway	NOUN
bjp-23039	431	3	alterations	alteration	NOUN
bjp-23039	431	4	in	in	ADP
bjp-23039	431	5	cancer	cancer	NOUN
bjp-23039	431	6	:	:	PUNCT
bjp-23039	431	7	variations	variation	NOUN
bjp-23039	431	8	on	on	ADP
bjp-23039	431	9	a	a	DET
bjp-23039	431	10	theme	theme	NOUN
bjp-23039	431	11	.	.	PUNCT
bjp-23039	432	1	oncogene	oncogene	NOUN
bjp-23039	432	2	2008	2008	NUM
bjp-23039	432	3	;	;	PUNCT
bjp-23039	432	4	27	27	NUM
bjp-23039	432	5	:	:	SYM
bjp-23039	432	6	5497	5497	NUM
bjp-23039	432	7	-	-	SYM
bjp-23039	432	8	510	510	NUM
bjp-23039	432	9	.	.	PUNCT
bjp-23039	433	1	zhang	zhang	PROPN
bjp-23039	433	2	l	l	PROPN
bjp-23039	433	3	,	,	PUNCT
bjp-23039	433	4	yu	yu	PROPN
bjp-23039	433	5	j	j	PROPN
bjp-23039	433	6	,	,	PUNCT
bjp-23039	433	7	park	park	NOUN
bjp-23039	433	8	bh	bh	PROPN
bjp-23039	433	9	,	,	PUNCT
bjp-23039	433	10	kinzler	kinzler	NOUN
bjp-23039	433	11	kw	kw	PROPN
bjp-23039	433	12	,	,	PUNCT
bjp-23039	433	13	vogelstein	vogelstein	PROPN
bjp-23039	433	14	b.	b.	PROPN
bjp-23039	433	15	role	role	NOUN
bjp-23039	433	16	of	of	ADP
bjp-23039	433	17	bax	bax	PROPN
bjp-23039	433	18	in	in	ADP
bjp-23039	433	19	the	the	DET
bjp-23039	433	20	apoptotic	apoptotic	ADJ
bjp-23039	433	21	response	response	NOUN
bjp-23039	433	22	to	to	PART
bjp-23039	433	23	anticancer	anticancer	NOUN
bjp-23039	433	24	agents	agent	NOUN
bjp-23039	433	25	.	.	PUNCT
bjp-23039	434	1	science	science	NOUN
bjp-23039	434	2	2000	2000	NUM
bjp-23039	434	3	;	;	PUNCT
bjp-23039	434	4	290	290	NUM
bjp-23039	434	5	:	:	SYM
bjp-23039	434	6	989	989	NUM
bjp-23039	434	7	-	-	SYM
bjp-23039	434	8	92	92	NUM
bjp-23039	434	9	.	.	PUNCT
bjp-23039	435	1	zhang	zhang	PROPN
bjp-23039	435	2	c	c	PROPN
bjp-23039	435	3	,	,	PUNCT
bjp-23039	435	4	yang	yang	PROPN
bjp-23039	435	5	l	l	PROPN
bjp-23039	435	6	,	,	PUNCT
bjp-23039	435	7	wang	wang	PROPN
bjp-23039	435	8	xb	xb	PROPN
bjp-23039	435	9	,	,	PUNCT
bjp-23039	435	10	wang	wang	PROPN
bjp-23039	435	11	js	js	PROPN
bjp-23039	435	12	,	,	PUNCT
bjp-23039	435	13	geng	geng	PROPN
bjp-23039	435	14	yd	yd	PROPN
bjp-23039	435	15	,	,	PUNCT
bjp-23039	435	16	yang	yang	PROPN
bjp-23039	435	17	cs	cs	PROPN
bjp-23039	435	18	,	,	PUNCT
bjp-23039	435	19	kong	kong	PROPN
bjp-23039	435	20	ly	ly	PROPN
bjp-23039	435	21	.	.	PUNCT
bjp-23039	436	1	calyxin	calyxin	PROPN
bjp-23039	436	2	y	y	PROPN
bjp-23039	436	3	induces	induce	VERB
bjp-23039	436	4	hydrogen	hydrogen	NOUN
bjp-23039	436	5	peroxide	peroxide	NOUN
bjp-23039	436	6	-	-	PUNCT
bjp-23039	436	7	dependent	dependent	ADJ
bjp-23039	436	8	autophagy	autophagy	NOUN
bjp-23039	436	9	and	and	CCONJ
bjp-23039	436	10	apoptosis	apoptosis	NOUN
bjp-23039	436	11	via	via	ADP
bjp-23039	436	12	jnk	jnk	PROPN
bjp-23039	436	13	activation	activation	NOUN
bjp-23039	436	14	in	in	ADP
bjp-23039	436	15	human	human	ADJ
bjp-23039	436	16	nonsmall	nonsmall	NOUN
bjp-23039	436	17	cell	cell	NOUN
bjp-23039	436	18	lung	lung	NOUN
bjp-23039	436	19	cancer	cancer	NOUN
bjp-23039	436	20	nci	nci	PROPN
bjp-23039	436	21	-	-	PUNCT
bjp-23039	436	22	h460	h460	PROPN
bjp-23039	436	23	cells	cell	NOUN
bjp-23039	436	24	.	.	PUNCT
bjp-23039	437	1	cancer	cancer	PROPN
bjp-23039	437	2	lett	lett	PROPN
bjp-23039	437	3	.	.	PUNCT
bjp-23039	438	1	2013	2013	NUM
bjp-23039	438	2	;	;	PUNCT
bjp-23039	438	3	340	340	NUM
bjp-23039	438	4	:	:	PUNCT
bjp-23039	438	5	51	51	NUM
bjp-23039	438	6	-	-	SYM
bjp-23039	438	7	62	62	NUM
bjp-23039	438	8	.	.	PUNCT
bjp-23039	439	1	zhang	zhang	PROPN
bjp-23039	439	2	j	j	PROPN
bjp-23039	439	3	,	,	PUNCT
bjp-23039	439	4	yu	yu	PROPN
bjp-23039	439	5	xh	xh	PROPN
bjp-23039	439	6	,	,	PUNCT
bjp-23039	439	7	yan	yan	PROPN
bjp-23039	439	8	yg	yg	PROPN
bjp-23039	439	9	,	,	PUNCT
bjp-23039	439	10	wang	wang	PROPN
bjp-23039	439	11	c	c	PROPN
bjp-23039	439	12	,	,	PUNCT
bjp-23039	439	13	wang	wang	PROPN
bjp-23039	439	14	wj	wj	PROPN
bjp-23039	439	15	.	.	PUNCT
bjp-23039	440	1	pi3k	pi3k	PROPN
bjp-23039	440	2	/	/	SYM
bjp-23039	440	3	akt	akt	PROPN
bjp-23039	440	4	signaling	signal	VERB
bjp-23039	440	5	in	in	ADP
bjp-23039	440	6	osteosarcoma	osteosarcoma	ADJ
bjp-23039	440	7	clin	clin	PROPN
bjp-23039	440	8	chim	chim	PROPN
bjp-23039	440	9	acta	acta	PROPN
bjp-23039	440	10	.	.	PUNCT
bjp-23039	441	1	2015	2015	NUM
bjp-23039	441	2	;	;	PUNCT
bjp-23039	441	3	444	444	NUM
bjp-23039	441	4	:	:	SYM
bjp-23039	441	5	182	182	NUM
bjp-23039	441	6	-	-	SYM
bjp-23039	441	7	92	92	NUM
bjp-23039	441	8	.	.	PUNCT
bjp-23039	442	1	zhao	zhao	PROPN
bjp-23039	442	2	x	x	PROPN
bjp-23039	442	3	,	,	PUNCT
bjp-23039	442	4	ma	ma	PROPN
bjp-23039	442	5	s	s	PROPN
bjp-23039	442	6	,	,	PUNCT
bjp-23039	442	7	liu	liu	PROPN
bjp-23039	442	8	n	n	PROPN
bjp-23039	442	9	,	,	PUNCT
bjp-23039	442	10	liu	liu	PROPN
bjp-23039	442	11	j	j	PROPN
bjp-23039	442	12	,	,	PUNCT
bjp-23039	442	13	wang	wang	PROPN
bjp-23039	442	14	w.	w.	PROPN
bjp-23039	442	15	a	a	DET
bjp-23039	442	16	polysaccharide	polysaccharide	NOUN
bjp-23039	442	17	from	from	ADP
bjp-23039	442	18	trametes	tramete	NOUN
bjp-23039	442	19	robiniophila	robiniophila	PROPN
bjp-23039	442	20	inhibits	inhibit	VERB
bjp-23039	442	21	human	human	ADJ
bjp-23039	442	22	osteosarcoma	osteosarcoma	ADJ
bjp-23039	442	23	xenograft	xenograft	NOUN
bjp-23039	442	24	tumor	tumor	NOUN
bjp-23039	442	25	growth	growth	NOUN
bjp-23039	442	26	in	in	ADP
bjp-23039	442	27	vivo	vivo	NOUN
bjp-23039	442	28	.	.	PUNCT
bjp-23039	443	1	carbohydrate	carbohydrate	NOUN
bjp-23039	443	2	polymers	polymer	NOUN
bjp-23039	443	3	.	.	PUNCT
bjp-23039	444	1	2015	2015	NUM
bjp-23039	444	2	;	;	PUNCT
bjp-23039	444	3	124	124	NUM
bjp-23039	444	4	:	:	SYM
bjp-23039	444	5	157	157	NUM
bjp-23039	444	6	-	-	SYM
bjp-23039	444	7	63	63	NUM
bjp-23039	444	8	.	.	PUNCT
bjp-23039	445	1	bangladesh	bangladesh	PROPN
bjp-23039	445	2	j	j	PROPN
bjp-23039	445	3	pharmacol	pharmacol	PROPN
bjp-23039	445	4	2015	2015	NUM
bjp-23039	445	5	;	;	PUNCT
bjp-23039	445	6	10	10	NUM
bjp-23039	445	7	:	:	SYM
bjp-23039	445	8	820	820	NUM
bjp-23039	445	9	-	-	SYM
bjp-23039	445	10	829	829	NUM
bjp-23039	445	11	829	829	NUM
bjp-23039	445	12	dateprinted	dateprinte	VERB
bjp-23039	445	13	:	:	PUNCT
bjp-23039	445	14	this	this	DET
bjp-23039	445	15	article	article	NOUN
bjp-23039	445	16	was	be	AUX
bjp-23039	445	17	downloaded	download	VERB
bjp-23039	445	18	by	by	ADP
bjp-23039	445	19	you	you	PRON
bjp-23039	445	20	on	on	ADP
bjp-23039	445	21	:	:	PUNCT
bjp-23039	445	22	sep	sep	PROPN
bjp-23039	445	23	29	29	NUM
bjp-23039	445	24	,	,	PUNCT
bjp-23039	445	25	2018	2018	NUM