id	sid	tid	token	lemma	pos
bjp-23981	1	1	bangladesh	bangladesh	PROPN
bjp-23981	1	2	journal	journal	PROPN
bjp-23981	1	3	of	of	ADP
bjp-23981	1	4	pharmacology	pharmacology	NOUN
bjp-23981	1	5	research	research	NOUN
bjp-23981	1	6	article	article	NOUN
bjp-23981	1	7	in	in	ADP
bjp-23981	1	8	silico	silico	NOUN
bjp-23981	1	9	in	in	ADP
bjp-23981	1	10	silico	silico	NOUN
bjp-23981	1	11	in	in	ADP
bjp-23981	1	12	silico	silico	NOUN
bjp-23981	1	13	and	and	CCONJ
bjp-23981	1	14	antithrombotic	antithrombotic	ADJ
bjp-23981	1	15	studies	study	NOUN
bjp-23981	1	16	and	and	CCONJ
bjp-23981	1	17	antithrombotic	antithrombotic	ADJ
bjp-23981	1	18	studies	study	NOUN
bjp-23981	1	19	and	and	CCONJ
bjp-23981	1	20	antithrombotic	antithrombotic	ADJ
bjp-23981	1	21	studies	study	NOUN
bjp-23981	1	22	of	of	ADP
bjp-23981	1	23	1,3,4of	1,3,4of	ADJ
bjp-23981	1	24	1,3,4of	1,3,4of	ADJ
bjp-23981	1	25	1,3,4	1,3,4	NUM
bjp-23981	1	26	-	-	SYM
bjp-23981	1	27	--oxadiazoles	--oxadiazole	NOUN
bjp-23981	1	28	derived	derive	VERB
bjp-23981	1	29	from	from	ADP
bjp-23981	1	30	oxadiazoles	oxadiazole	NOUN
bjp-23981	1	31	derived	derive	VERB
bjp-23981	1	32	from	from	ADP
bjp-23981	1	33	oxadiazoles	oxadiazole	NOUN
bjp-23981	1	34	derived	derive	VERB
bjp-23981	1	35	from	from	ADP
bjp-23981	1	36	benzimidazole	benzimidazole	PROPN
bjp-23981	1	37	benzimidazole	benzimidazole	PROPN
bjp-23981	1	38	benzimidazole	benzimidazole	PROPN
bjp-23981	1	39	bjp	bjp	PROPN
bjp-23981	1	40	introduction	introduction	NOUN
bjp-23981	1	41	arterial	arterial	ADJ
bjp-23981	1	42	thromboembolism	thromboembolism	NOUN
bjp-23981	1	43	is	be	AUX
bjp-23981	1	44	the	the	DET
bjp-23981	1	45	most	most	ADV
bjp-23981	1	46	common	common	ADJ
bjp-23981	1	47	cause	cause	NOUN
bjp-23981	1	48	of	of	ADP
bjp-23981	1	49	cardioembolic	cardioembolic	ADJ
bjp-23981	1	50	events	event	NOUN
bjp-23981	1	51	including	include	VERB
bjp-23981	1	52	myocardial	myocardial	ADJ
bjp-23981	1	53	infarction	infarction	NOUN
bjp-23981	1	54	,	,	PUNCT
bjp-23981	1	55	ischemic	ischemic	ADJ
bjp-23981	1	56	stroke	stroke	NOUN
bjp-23981	1	57	and	and	CCONJ
bjp-23981	1	58	limb	limb	NOUN
bjp-23981	1	59	gangrene	gangrene	NOUN
bjp-23981	1	60	.	.	PUNCT
bjp-23981	2	1	thus	thus	ADV
bjp-23981	2	2	,	,	PUNCT
bjp-23981	2	3	arterial	arterial	ADJ
bjp-23981	2	4	thromboembolism	thromboembolism	NOUN
bjp-23981	2	5	is	be	AUX
bjp-23981	2	6	obviously	obviously	ADV
bjp-23981	2	7	the	the	DET
bjp-23981	2	8	leading	lead	VERB
bjp-23981	2	9	causes	cause	NOUN
bjp-23981	2	10	of	of	ADP
bjp-23981	2	11	morbidity	morbidity	NOUN
bjp-23981	2	12	and	and	CCONJ
bjp-23981	2	13	mortality	mortality	NOUN
bjp-23981	2	14	world	world	NOUN
bjp-23981	2	15	-	-	PUNCT
bjp-23981	2	16	wide	wide	ADV
bjp-23981	2	17	(	(	PUNCT
bjp-23981	2	18	murray	murray	NOUN
bjp-23981	2	19	and	and	CCONJ
bjp-23981	2	20	lopez	lopez	NOUN
bjp-23981	2	21	,	,	PUNCT
bjp-23981	2	22	1997	1997	NUM
bjp-23981	2	23	)	)	PUNCT
bjp-23981	2	24	.	.	PUNCT
bjp-23981	3	1	the	the	DET
bjp-23981	3	2	management	management	NOUN
bjp-23981	3	3	of	of	ADP
bjp-23981	3	4	ischemic	ischemic	ADJ
bjp-23981	3	5	heart	heart	NOUN
bjp-23981	3	6	diseases	disease	NOUN
bjp-23981	3	7	is	be	AUX
bjp-23981	3	8	now	now	ADV
bjp-23981	3	9	flanked	flank	VERB
bjp-23981	3	10	by	by	ADP
bjp-23981	3	11	newer	new	ADJ
bjp-23981	3	12	,	,	PUNCT
bjp-23981	3	13	more	more	ADV
bjp-23981	3	14	aggressive	aggressive	ADJ
bjp-23981	3	15	forms	form	NOUN
bjp-23981	3	16	of	of	ADP
bjp-23981	3	17	therapy	therapy	NOUN
bjp-23981	3	18	,	,	PUNCT
bjp-23981	3	19	which	which	PRON
bjp-23981	3	20	includes	include	VERB
bjp-23981	3	21	the	the	DET
bjp-23981	3	22	early	early	ADJ
bjp-23981	3	23	administration	administration	NOUN
bjp-23981	3	24	of	of	ADP
bjp-23981	3	25	thrombolytic	thrombolytic	ADJ
bjp-23981	3	26	drugs	drug	NOUN
bjp-23981	3	27	.	.	PUNCT
bjp-23981	4	1	clinical	clinical	ADJ
bjp-23981	4	2	research	research	NOUN
bjp-23981	4	3	have	have	AUX
bjp-23981	4	4	focused	focus	VERB
bjp-23981	4	5	on	on	ADP
bjp-23981	4	6	developing	develop	VERB
bjp-23981	4	7	techniques	technique	NOUN
bjp-23981	4	8	that	that	PRON
bjp-23981	4	9	directly	directly	ADV
bjp-23981	4	10	restore	restore	VERB
bjp-23981	4	11	nutritive	nutritive	ADJ
bjp-23981	4	12	myocardial	myocardial	ADJ
bjp-23981	4	13	perfusion	perfusion	NOUN
bjp-23981	4	14	,	,	PUNCT
bjp-23981	4	15	in	in	ADP
bjp-23981	4	16	particular	particular	ADJ
bjp-23981	4	17	,	,	PUNCT
bjp-23981	4	18	drugs	drug	NOUN
bjp-23981	4	19	capable	capable	ADJ
bjp-23981	4	20	of	of	ADP
bjp-23981	4	21	lysing	lyse	VERB
bjp-23981	4	22	the	the	DET
bjp-23981	4	23	intracoronary	intracoronary	ADJ
bjp-23981	4	24	thrombus	thrombus	NOUN
bjp-23981	4	25	(	(	PUNCT
bjp-23981	4	26	meschia	meschia	NOUN
bjp-23981	4	27	et	et	PROPN
bjp-23981	4	28	al	al	PROPN
bjp-23981	4	29	.	.	PROPN
bjp-23981	4	30	,	,	PUNCT
bjp-23981	4	31	2002	2002	NUM
bjp-23981	4	32	)	)	PUNCT
bjp-23981	4	33	.	.	PUNCT
bjp-23981	5	1	the	the	DET
bjp-23981	5	2	treatment	treatment	NOUN
bjp-23981	5	3	of	of	ADP
bjp-23981	5	4	acute	acute	ADJ
bjp-23981	5	5	myocardial	myocardial	ADJ
bjp-23981	5	6	infarction	infarction	NOUN
bjp-23981	5	7	has	have	AUX
bjp-23981	5	8	changed	change	VERB
bjp-23981	5	9	during	during	ADP
bjp-23981	5	10	the	the	DET
bjp-23981	5	11	past	past	ADJ
bjp-23981	5	12	decade	decade	NOUN
bjp-23981	5	13	as	as	SCONJ
bjp-23981	5	14	newer	new	ADJ
bjp-23981	5	15	approaches	approach	NOUN
bjp-23981	5	16	have	have	AUX
bjp-23981	5	17	become	become	VERB
bjp-23981	5	18	accessible	accessible	ADJ
bjp-23981	5	19	,	,	PUNCT
bjp-23981	5	20	as	as	SCONJ
bjp-23981	5	21	prevention	prevention	NOUN
bjp-23981	5	22	of	of	ADP
bjp-23981	5	23	complications	complication	NOUN
bjp-23981	5	24	has	have	AUX
bjp-23981	5	25	been	be	AUX
bjp-23981	5	26	the	the	DET
bjp-23981	5	27	cornerstones	cornerstone	NOUN
bjp-23981	5	28	for	for	ADP
bjp-23981	5	29	treatment	treatment	NOUN
bjp-23981	5	30	(	(	PUNCT
bjp-23981	5	31	godfrey	godfrey	PROPN
bjp-23981	5	32	et	et	PROPN
bjp-23981	5	33	al	al	PROPN
bjp-23981	5	34	.	.	PROPN
bjp-23981	5	35	,	,	PUNCT
bjp-23981	5	36	2011	2011	NUM
bjp-23981	5	37	)	)	PUNCT
bjp-23981	5	38	.	.	PUNCT
bjp-23981	6	1	thrombolytic	thrombolytic	ADJ
bjp-23981	6	2	agents	agent	NOUN
bjp-23981	6	3	are	be	AUX
bjp-23981	6	4	used	use	VERB
bjp-23981	6	5	to	to	ADP
bjp-23981	6	6	lyse	lyse	PROPN
bjp-23981	6	7	already	already	ADV
bjp-23981	6	8	formed	form	VERB
bjp-23981	6	9	blood	blood	NOUN
bjp-23981	6	10	clots	clot	NOUN
bjp-23981	6	11	in	in	ADP
bjp-23981	6	12	clinical	clinical	ADJ
bjp-23981	6	13	settings	setting	NOUN
bjp-23981	6	14	where	where	SCONJ
bjp-23981	6	15	ischemia	ischemia	NOUN
bjp-23981	6	16	may	may	AUX
bjp-23981	6	17	be	be	AUX
bjp-23981	6	18	fatal	fatal	ADJ
bjp-23981	6	19	(	(	PUNCT
bjp-23981	6	20	acute	acute	ADJ
bjp-23981	6	21	mycardial	mycardial	ADJ
bjp-23981	6	22	infarction	infarction	NOUN
bjp-23981	6	23	,	,	PUNCT
bjp-23981	6	24	pulmonary	pulmonary	ADJ
bjp-23981	6	25	embolism	embolism	NOUN
bjp-23981	6	26	,	,	PUNCT
bjp-23981	6	27	ischemic	ischemic	ADJ
bjp-23981	6	28	stroke	stroke	NOUN
bjp-23981	6	29	,	,	PUNCT
bjp-23981	6	30	and	and	CCONJ
bjp-23981	6	31	arterial	arterial	ADJ
bjp-23981	6	32	thrombosis	thrombosis	NOUN
bjp-23981	6	33	)	)	PUNCT
bjp-23981	6	34	.	.	PUNCT
bjp-23981	7	1	this	this	DET
bjp-23981	7	2	method	method	NOUN
bjp-23981	7	3	seems	seem	VERB
bjp-23981	7	4	to	to	PART
bjp-23981	7	5	be	be	AUX
bjp-23981	7	6	most	most	ADV
bjp-23981	7	7	attractive	attractive	ADJ
bjp-23981	7	8	because	because	SCONJ
bjp-23981	7	9	of	of	ADP
bjp-23981	7	10	its	its	PRON
bjp-23981	7	11	simplicity	simplicity	NOUN
bjp-23981	7	12	,	,	PUNCT
bjp-23981	7	13	which	which	PRON
bjp-23981	7	14	makes	make	VERB
bjp-23981	7	15	it	it	PRON
bjp-23981	7	16	suitable	suitable	ADJ
bjp-23981	7	17	for	for	ADP
bjp-23981	7	18	the	the	DET
bjp-23981	7	19	vast	vast	ADJ
bjp-23981	7	20	majority	majority	NOUN
bjp-23981	7	21	of	of	ADP
bjp-23981	7	22	patients	patient	NOUN
bjp-23981	7	23	with	with	ADP
bjp-23981	7	24	acute	acute	ADJ
bjp-23981	7	25	myocardial	myocardial	ADJ
bjp-23981	7	26	infarction	infarction	NOUN
bjp-23981	7	27	.	.	PUNCT
bjp-23981	8	1	thus	thus	ADV
bjp-23981	8	2	,	,	PUNCT
bjp-23981	8	3	highlighting	highlight	VERB
bjp-23981	8	4	the	the	DET
bjp-23981	8	5	clinical	clinical	ADJ
bjp-23981	8	6	advantage	advantage	NOUN
bjp-23981	8	7	of	of	ADP
bjp-23981	8	8	thrombolytic	thrombolytic	ADJ
bjp-23981	8	9	agents	agent	NOUN
bjp-23981	8	10	,	,	PUNCT
bjp-23981	8	11	this	this	DET
bjp-23981	8	12	process	process	NOUN
bjp-23981	8	13	of	of	ADP
bjp-23981	8	14	clot	clot	NOUN
bjp-23981	8	15	dissolution	dissolution	NOUN
bjp-23981	8	16	is	be	AUX
bjp-23981	8	17	accomplished	accomplish	VERB
bjp-23981	8	18	by	by	ADP
bjp-23981	8	19	the	the	DET
bjp-23981	8	20	enzyme	enzyme	NOUN
bjp-23981	8	21	plasmin	plasmin	NOUN
bjp-23981	8	22	that	that	PRON
bjp-23981	8	23	digests	digest	VERB
bjp-23981	8	24	the	the	DET
bjp-23981	8	25	fibrin	fibrin	NOUN
bjp-23981	8	26	strands	strand	NOUN
bjp-23981	8	27	of	of	ADP
bjp-23981	8	28	the	the	DET
bjp-23981	8	29	clot	clot	NOUN
bjp-23981	8	30	.	.	PUNCT
bjp-23981	9	1	thrombolytic	thrombolytic	ADJ
bjp-23981	9	2	drugs	drug	NOUN
bjp-23981	9	3	like	like	ADP
bjp-23981	9	4	tissue	tissue	NOUN
bjp-23981	9	5	plasminogen	plasminogen	NOUN
bjp-23981	9	6	activator	activator	NOUN
bjp-23981	9	7	(	(	PUNCT
bjp-23981	9	8	t	t	NOUN
bjp-23981	9	9	-pa	-pa	NOUN
bjp-23981	9	10	)	)	PUNCT
bjp-23981	9	11	,	,	PUNCT
bjp-23981	9	12	urokinase	urokinase	NOUN
bjp-23981	9	13	,	,	PUNCT
bjp-23981	9	14	streptokinase	streptokinase	PROPN
bjp-23981	9	15	etc	etc	X
bjp-23981	9	16	.	.	X
bjp-23981	9	17	,	,	PUNCT
bjp-23981	9	18	play	play	VERB
bjp-23981	9	19	a	a	DET
bjp-23981	9	20	crucial	crucial	ADJ
bjp-23981	9	21	role	role	NOUN
bjp-23981	9	22	in	in	ADP
bjp-23981	9	23	a	a	DET
bjp-23981	9	24	journal	journal	NOUN
bjp-23981	9	25	of	of	ADP
bjp-23981	9	26	the	the	DET
bjp-23981	9	27	bangladesh	bangladesh	NOUN
bjp-23981	9	28	pharmacological	pharmacological	ADJ
bjp-23981	9	29	society	society	NOUN
bjp-23981	9	30	(	(	PUNCT
bjp-23981	9	31	bdps	bdps	NOUN
bjp-23981	9	32	)	)	PUNCT
bjp-23981	9	33	bangladesh	bangladesh	PROPN
bjp-23981	9	34	j	j	PROPN
bjp-23981	9	35	pharmacol	pharmacol	PROPN
bjp-23981	9	36	2016	2016	NUM
bjp-23981	9	37	;	;	PUNCT
bjp-23981	9	38	11	11	NUM
bjp-23981	9	39	:	:	SYM
bjp-23981	9	40	67	67	NUM
bjp-23981	9	41	-	-	SYM
bjp-23981	9	42	74	74	NUM
bjp-23981	9	43	journal	journal	NOUN
bjp-23981	9	44	homepage	homepage	NOUN
bjp-23981	9	45	:	:	PUNCT
bjp-23981	9	46	www.banglajol.info	www.banglajol.info	PROPN
bjp-23981	9	47	abstracted	abstract	VERB
bjp-23981	9	48	/	/	SYM
bjp-23981	9	49	indexed	index	VERB
bjp-23981	9	50	in	in	ADP
bjp-23981	9	51	academic	academic	ADJ
bjp-23981	9	52	search	search	NOUN
bjp-23981	9	53	complete	complete	ADJ
bjp-23981	9	54	,	,	PUNCT
bjp-23981	9	55	asia	asia	PROPN
bjp-23981	9	56	journals	journal	NOUN
bjp-23981	9	57	online	online	ADV
bjp-23981	9	58	,	,	PUNCT
bjp-23981	9	59	bangladesh	bangladesh	NOUN
bjp-23981	9	60	journals	journal	NOUN
bjp-23981	9	61	online	online	ADV
bjp-23981	9	62	,	,	PUNCT
bjp-23981	9	63	biological	biological	ADJ
bjp-23981	9	64	abstracts	abstract	NOUN
bjp-23981	9	65	,	,	PUNCT
bjp-23981	9	66	biosis	biosis	NOUN
bjp-23981	9	67	previews	preview	NOUN
bjp-23981	9	68	,	,	PUNCT
bjp-23981	9	69	cab	cab	NOUN
bjp-23981	9	70	abstracts	abstract	NOUN
bjp-23981	9	71	,	,	PUNCT
bjp-23981	9	72	current	current	ADJ
bjp-23981	9	73	abstracts	abstract	NOUN
bjp-23981	9	74	,	,	PUNCT
bjp-23981	9	75	directory	directory	NOUN
bjp-23981	9	76	of	of	ADP
bjp-23981	9	77	open	open	ADJ
bjp-23981	9	78	access	access	NOUN
bjp-23981	9	79	journals	journal	NOUN
bjp-23981	9	80	,	,	PUNCT
bjp-23981	9	81	embase	embase	NOUN
bjp-23981	9	82	/	/	SYM
bjp-23981	9	83	excerpta	excerpta	NOUN
bjp-23981	9	84	medica	medica	NOUN
bjp-23981	9	85	,	,	PUNCT
bjp-23981	9	86	google	google	PROPN
bjp-23981	9	87	scholar	scholar	NOUN
bjp-23981	9	88	,	,	PUNCT
bjp-23981	9	89	hinari	hinari	X
bjp-23981	9	90	(	(	PUNCT
bjp-23981	9	91	who	who	PRON
bjp-23981	9	92	)	)	PUNCT
bjp-23981	9	93	,	,	PUNCT
bjp-23981	9	94	international	international	ADJ
bjp-23981	9	95	pharmaceutical	pharmaceutical	ADJ
bjp-23981	9	96	abstracts	abstract	NOUN
bjp-23981	9	97	,	,	PUNCT
bjp-23981	9	98	open	open	ADJ
bjp-23981	9	99	j	j	PROPN
bjp-23981	9	100	-	-	PUNCT
bjp-23981	9	101	gate	gate	NOUN
bjp-23981	9	102	,	,	PUNCT
bjp-23981	9	103	science	science	NOUN
bjp-23981	9	104	citation	citation	NOUN
bjp-23981	9	105	index	index	NOUN
bjp-23981	9	106	expanded	expand	VERB
bjp-23981	9	107	,	,	PUNCT
bjp-23981	9	108	scopus	scopus	NOUN
bjp-23981	9	109	and	and	CCONJ
bjp-23981	9	110	social	social	ADJ
bjp-23981	9	111	sciences	sciences	PROPN
bjp-23981	9	112	citation	citation	NOUN
bjp-23981	9	113	index	index	NOUN
bjp-23981	9	114	;	;	PUNCT
bjp-23981	9	115	issn	issn	PROPN
bjp-23981	9	116	:	:	PUNCT
bjp-23981	9	117	1991	1991	NUM
bjp-23981	9	118	-	-	SYM
bjp-23981	9	119	0088	0088	NUM
bjp-23981	9	120	abstract	abstract	NOUN
bjp-23981	9	121	in	in	ADP
bjp-23981	9	122	the	the	DET
bjp-23981	9	123	present	present	ADJ
bjp-23981	9	124	study	study	NOUN
bjp-23981	9	125	,	,	PUNCT
bjp-23981	9	126	a	a	DET
bjp-23981	9	127	series	series	NOUN
bjp-23981	9	128	of	of	ADP
bjp-23981	9	129	1,3,4	1,3,4	NUM
bjp-23981	9	130	-	-	PUNCT
bjp-23981	9	131	oxadiazole	oxadiazole	NOUN
bjp-23981	9	132	derivatives	derivative	NOUN
bjp-23981	9	133	(	(	PUNCT
bjp-23981	9	134	4a-4k	4a-4k	NUM
bjp-23981	9	135	)	)	PUNCT
bjp-23981	9	136	derived	derive	VERB
bjp-23981	9	137	from	from	ADP
bjp-23981	9	138	benzimidazole	benzimidazole	NOUN
bjp-23981	9	139	were	be	AUX
bjp-23981	9	140	docked	dock	VERB
bjp-23981	9	141	onto	onto	ADP
bjp-23981	9	142	factor	factor	NOUN
bjp-23981	9	143	xa	xa	PROPN
bjp-23981	9	144	(	(	PUNCT
bjp-23981	9	145	pdb	pdb	NOUN
bjp-23981	9	146	:	:	PUNCT
bjp-23981	9	147	1nfy	1nfy	NUM
bjp-23981	9	148	)	)	PUNCT
bjp-23981	9	149	protein	protein	NOUN
bjp-23981	9	150	using	use	VERB
bjp-23981	9	151	sybylx	sybylx	NOUN
bjp-23981	9	152	2.1	2.1	NUM
bjp-23981	9	153	.	.	PUNCT
bjp-23981	9	154	and	and	CCONJ
bjp-23981	9	155	also	also	ADV
bjp-23981	9	156	evaluated	evaluate	VERB
bjp-23981	9	157	for	for	ADP
bjp-23981	9	158	in	in	ADP
bjp-23981	9	159	vitro	vitro	X
bjp-23981	9	160	clot	clot	NOUN
bjp-23981	9	161	lysis	lysis	NOUN
bjp-23981	9	162	for	for	ADP
bjp-23981	9	163	thrombolytic	thrombolytic	ADJ
bjp-23981	9	164	activity	activity	NOUN
bjp-23981	9	165	.	.	PUNCT
bjp-23981	10	1	the	the	DET
bjp-23981	10	2	synthesized	synthesize	VERB
bjp-23981	10	3	molecules	molecule	NOUN
bjp-23981	10	4	were	be	AUX
bjp-23981	10	5	also	also	ADV
bjp-23981	10	6	screened	screen	VERB
bjp-23981	10	7	for	for	ADP
bjp-23981	10	8	in	in	ADP
bjp-23981	10	9	silico	silico	NOUN
bjp-23981	10	10	adme	adme	NOUN
bjp-23981	10	11	studies	study	NOUN
bjp-23981	10	12	.	.	PUNCT
bjp-23981	11	1	the	the	DET
bjp-23981	11	2	molecular	molecular	ADJ
bjp-23981	11	3	docking	docking	NOUN
bjp-23981	11	4	studies	study	NOUN
bjp-23981	11	5	highlighted	highlight	VERB
bjp-23981	11	6	that	that	SCONJ
bjp-23981	11	7	the	the	DET
bjp-23981	11	8	molecules	molecule	NOUN
bjp-23981	11	9	showed	show	VERB
bjp-23981	11	10	high	high	ADJ
bjp-23981	11	11	affinity	affinity	NOUN
bjp-23981	11	12	towards	towards	ADP
bjp-23981	11	13	1nfy	1nfy	NUM
bjp-23981	11	14	with	with	ADP
bjp-23981	11	15	higher	high	ADJ
bjp-23981	11	16	docking	docking	NOUN
bjp-23981	11	17	score	score	NOUN
bjp-23981	11	18	and	and	CCONJ
bjp-23981	11	19	the	the	DET
bjp-23981	11	20	in	in	ADP
bjp-23981	11	21	silico	silico	NOUN
bjp-23981	11	22	adme	adme	NOUN
bjp-23981	11	23	results	result	NOUN
bjp-23981	11	24	were	be	AUX
bjp-23981	11	25	promising	promise	VERB
bjp-23981	11	26	and	and	CCONJ
bjp-23981	11	27	indicated	indicate	VERB
bjp-23981	11	28	that	that	SCONJ
bjp-23981	11	29	the	the	DET
bjp-23981	11	30	molecules	molecule	NOUN
bjp-23981	11	31	holds	hold	VERB
bjp-23981	11	32	great	great	ADJ
bjp-23981	11	33	potential	potential	NOUN
bjp-23981	11	34	as	as	ADP
bjp-23981	11	35	a	a	DET
bjp-23981	11	36	drug	drug	NOUN
bjp-23981	11	37	candidate	candidate	NOUN
bjp-23981	11	38	.	.	PUNCT
bjp-23981	12	1	the	the	DET
bjp-23981	12	2	thrombolytic	thrombolytic	ADJ
bjp-23981	12	3	evaluation	evaluation	NOUN
bjp-23981	12	4	was	be	AUX
bjp-23981	12	5	performed	perform	VERB
bjp-23981	12	6	for	for	ADP
bjp-23981	12	7	decrease	decrease	NOUN
bjp-23981	12	8	in	in	ADP
bjp-23981	12	9	solid	solid	ADJ
bjp-23981	12	10	clot	clot	NOUN
bjp-23981	12	11	weight	weight	NOUN
bjp-23981	12	12	by	by	ADP
bjp-23981	12	13	the	the	DET
bjp-23981	12	14	clot	clot	NOUN
bjp-23981	12	15	lysis	lysis	NOUN
bjp-23981	12	16	study	study	NOUN
bjp-23981	12	17	at	at	ADP
bjp-23981	12	18	a	a	DET
bjp-23981	12	19	concentration	concentration	NOUN
bjp-23981	12	20	of	of	ADP
bjp-23981	12	21	6.25	6.25	NUM
bjp-23981	12	22	,	,	PUNCT
bjp-23981	12	23	12.5	12.5	NUM
bjp-23981	12	24	and	and	CCONJ
bjp-23981	12	25	25	25	NUM
bjp-23981	12	26	µm	µm	NOUN
bjp-23981	12	27	strengths	strength	NOUN
bjp-23981	12	28	,	,	PUNCT
bjp-23981	12	29	respectively	respectively	ADV
bjp-23981	12	30	.	.	PUNCT
bjp-23981	13	1	the	the	DET
bjp-23981	13	2	results	result	NOUN
bjp-23981	13	3	of	of	ADP
bjp-23981	13	4	in	in	ADP
bjp-23981	13	5	vitro	vitro	X
bjp-23981	13	6	clot	clot	NOUN
bjp-23981	13	7	lysis	lysis	NOUN
bjp-23981	13	8	for	for	ADP
bjp-23981	13	9	thrombolytic	thrombolytic	ADJ
bjp-23981	13	10	evaluation	evaluation	NOUN
bjp-23981	13	11	revealed	reveal	VERB
bjp-23981	13	12	that	that	SCONJ
bjp-23981	13	13	the	the	DET
bjp-23981	13	14	tested	test	VERB
bjp-23981	13	15	compounds	compound	NOUN
bjp-23981	13	16	4a-4k	4a-4k	PRON
bjp-23981	13	17	exhibited	exhibit	VERB
bjp-23981	13	18	significant	significant	ADJ
bjp-23981	13	19	clot	clot	NOUN
bjp-23981	13	20	lysis	lysis	NOUN
bjp-23981	13	21	with	with	ADP
bjp-23981	13	22	respect	respect	NOUN
bjp-23981	13	23	to	to	ADP
bjp-23981	13	24	negative	negative	ADJ
bjp-23981	13	25	control	control	NOUN
bjp-23981	13	26	phosphate	phosphate	ADJ
bjp-23981	13	27	buffered	buffer	VERB
bjp-23981	13	28	saline	saline	NOUN
bjp-23981	13	29	and	and	CCONJ
bjp-23981	13	30	in	in	ADP
bjp-23981	13	31	comparison	comparison	NOUN
bjp-23981	13	32	to	to	ADP
bjp-23981	13	33	the	the	DET
bjp-23981	13	34	reference	reference	NOUN
bjp-23981	13	35	drug	drug	NOUN
bjp-23981	13	36	streptokinase	streptokinase	PROPN
bjp-23981	13	37	(	(	PUNCT
bjp-23981	13	38	30,000	30,000	NUM
bjp-23981	13	39	iu	iu	NOUN
bjp-23981	13	40	)	)	PUNCT
bjp-23981	13	41	.	.	PUNCT
bjp-23981	14	1	among	among	ADP
bjp-23981	14	2	all	all	DET
bjp-23981	14	3	the	the	DET
bjp-23981	14	4	tested	test	VERB
bjp-23981	14	5	compounds	compound	NOUN
bjp-23981	14	6	,	,	PUNCT
bjp-23981	14	7	compound	compound	NOUN
bjp-23981	14	8	4j	4j	NOUN
bjp-23981	14	9	,	,	PUNCT
bjp-23981	14	10	4d	4d	NUM
bjp-23981	14	11	and	and	CCONJ
bjp-23981	14	12	4	4	NUM
bjp-23981	14	13	g	g	NOUN
bjp-23981	14	14	exhibited	exhibit	VERB
bjp-23981	14	15	potent	potent	ADJ
bjp-23981	14	16	thrombolytic	thrombolytic	ADJ
bjp-23981	14	17	activity	activity	NOUN
bjp-23981	14	18	with	with	ADP
bjp-23981	14	19	ec50	ec50	PROPN
bjp-23981	14	20	value	value	NOUN
bjp-23981	14	21	of	of	ADP
bjp-23981	14	22	16.2	16.2	NUM
bjp-23981	14	23	,	,	PUNCT
bjp-23981	14	24	18.1	18.1	NUM
bjp-23981	14	25	and	and	CCONJ
bjp-23981	14	26	23.7	23.7	NUM
bjp-23981	14	27	µm	µm	NOUN
bjp-23981	14	28	,	,	PUNCT
bjp-23981	14	29	respectively	respectively	ADV
bjp-23981	14	30	.	.	PUNCT
bjp-23981	15	1	the	the	DET
bjp-23981	15	2	thrombolytic	thrombolytic	ADJ
bjp-23981	15	3	efficacy	efficacy	NOUN
bjp-23981	15	4	investigation	investigation	NOUN
bjp-23981	15	5	highlights	highlight	VERB
bjp-23981	15	6	that	that	SCONJ
bjp-23981	15	7	the	the	DET
bjp-23981	15	8	synthesized	synthesize	VERB
bjp-23981	15	9	compound	compound	NOUN
bjp-23981	15	10	4j	4j	NOUN
bjp-23981	15	11	could	could	AUX
bjp-23981	15	12	be	be	AUX
bjp-23981	15	13	considered	consider	VERB
bjp-23981	15	14	for	for	SCONJ
bjp-23981	15	15	further	further	ADJ
bjp-23981	15	16	clinical	clinical	ADJ
bjp-23981	15	17	studies	study	NOUN
bjp-23981	15	18	to	to	PART
bjp-23981	15	19	ascertain	ascertain	VERB
bjp-23981	15	20	its	its	PRON
bjp-23981	15	21	possible	possible	ADJ
bjp-23981	15	22	hit	hit	NOUN
bjp-23981	15	23	as	as	ADP
bjp-23981	15	24	thrombolytic	thrombolytic	ADJ
bjp-23981	15	25	agents	agent	NOUN
bjp-23981	15	26	.	.	PUNCT
bjp-23981	16	1	article	article	NOUN
bjp-23981	16	2	info	info	NOUN
bjp-23981	16	3	received	receive	VERB
bjp-23981	16	4	:	:	PUNCT
bjp-23981	16	5	3	3	NUM
bjp-23981	16	6	july	july	PROPN
bjp-23981	16	7	2015	2015	NUM
bjp-23981	16	8	accepted	accept	VERB
bjp-23981	16	9	:	:	PUNCT
bjp-23981	16	10	21	21	NUM
bjp-23981	16	11	september	september	PROPN
bjp-23981	16	12	2015	2015	NUM
bjp-23981	16	13	available	available	ADJ
bjp-23981	16	14	online	online	NOUN
bjp-23981	16	15	:	:	PUNCT
bjp-23981	16	16	18	18	NUM
bjp-23981	16	17	december	december	PROPN
bjp-23981	16	18	2015	2015	NUM
bjp-23981	16	19	doi	doi	NOUN
bjp-23981	16	20	:	:	PUNCT
bjp-23981	16	21	10.3329	10.3329	NUM
bjp-23981	16	22	/	/	SYM
bjp-23981	16	23	bjp.v11i1.23981	bjp.v11i1.23981	PROPN
bjp-23981	16	24	cite	cite	VERB
bjp-23981	16	25	this	this	DET
bjp-23981	16	26	article	article	NOUN
bjp-23981	16	27	:	:	PUNCT
bjp-23981	16	28	vishwanathan	vishwanathan	PROPN
bjp-23981	16	29	b	b	PROPN
bjp-23981	16	30	,	,	PUNCT
bjp-23981	16	31	gurupadayya	gurupadayya	PROPN
bjp-23981	16	32	bm	bm	PROPN
bjp-23981	16	33	,	,	PUNCT
bjp-23981	16	34	sairam	sairam	PROPN
bjp-23981	16	35	kv	kv	PROPN
bjp-23981	16	36	.	.	PUNCT
bjp-23981	17	1	in	in	ADP
bjp-23981	17	2	silico	silico	NOUN
bjp-23981	17	3	and	and	CCONJ
bjp-23981	17	4	antithrombotic	antithrombotic	ADJ
bjp-23981	17	5	studies	study	NOUN
bjp-23981	17	6	of	of	ADP
bjp-23981	17	7	1,3,4	1,3,4	NUM
bjp-23981	17	8	-	-	PUNCT
bjp-23981	17	9	oxadiazoles	oxadiazole	NOUN
bjp-23981	17	10	derived	derive	VERB
bjp-23981	17	11	from	from	ADP
bjp-23981	17	12	benzimidazole	benzimidazole	PROPN
bjp-23981	17	13	.	.	PUNCT
bjp-23981	18	1	bangladesh	bangladesh	PROPN
bjp-23981	18	2	j	j	PROPN
bjp-23981	18	3	pharmacol	pharmacol	PROPN
bjp-23981	18	4	.	.	PROPN
bjp-23981	19	1	2016	2016	NUM
bjp-23981	19	2	;	;	PUNCT
bjp-23981	19	3	11	11	NUM
bjp-23981	19	4	:	:	SYM
bjp-23981	19	5	67	67	NUM
bjp-23981	19	6	-	-	SYM
bjp-23981	19	7	74	74	NUM
bjp-23981	19	8	.	.	PUNCT
bjp-23981	20	1	in	in	ADP
bjp-23981	20	2	silico	silico	NOUN
bjp-23981	20	3	and	and	CCONJ
bjp-23981	20	4	antithrombotic	antithrombotic	ADJ
bjp-23981	20	5	studies	study	NOUN
bjp-23981	20	6	of	of	ADP
bjp-23981	20	7	1,3,4	1,3,4	NUM
bjp-23981	20	8	-	-	PUNCT
bjp-23981	20	9	oxadiazoles	oxadiazole	NOUN
bjp-23981	20	10	derived	derive	VERB
bjp-23981	20	11	from	from	ADP
bjp-23981	20	12	benzimidazole	benzimidazole	PROPN
bjp-23981	20	13	b.	b.	PROPN
bjp-23981	20	14	vishwanathan	vishwanathan	PROPN
bjp-23981	20	15	,	,	PUNCT
bjp-23981	20	16	b.	b.	PROPN
bjp-23981	20	17	m.	m.	PROPN
bjp-23981	20	18	gurupadayya	gurupadayya	PROPN
bjp-23981	20	19	and	and	CCONJ
bjp-23981	20	20	k.	k.	PROPN
bjp-23981	20	21	venkata	venkata	PROPN
bjp-23981	20	22	sairam	sairam	PROPN
bjp-23981	20	23	department	department	PROPN
bjp-23981	20	24	of	of	ADP
bjp-23981	20	25	pharmaceutical	pharmaceutical	ADJ
bjp-23981	20	26	chemistry	chemistry	NOUN
bjp-23981	20	27	,	,	PUNCT
bjp-23981	20	28	jss	jss	PROPN
bjp-23981	20	29	college	college	PROPN
bjp-23981	20	30	of	of	ADP
bjp-23981	20	31	pharmacy	pharmacy	NOUN
bjp-23981	20	32	,	,	PUNCT
bjp-23981	20	33	jss	jss	PROPN
bjp-23981	20	34	university	university	PROPN
bjp-23981	20	35	,	,	PUNCT
bjp-23981	20	36	sri	sri	NOUN
bjp-23981	20	37	shivarathreeshwara	shivarathreeshwara	NOUN
bjp-23981	20	38	nagar	nagar	NOUN
bjp-23981	20	39	,	,	PUNCT
bjp-23981	20	40	mysore	mysore	NOUN
bjp-23981	20	41	,	,	PUNCT
bjp-23981	20	42	karnataka	karnataka	PROPN
bjp-23981	20	43	570	570	NUM
bjp-23981	20	44	015	015	NUM
bjp-23981	20	45	,	,	PUNCT
bjp-23981	20	46	india	india	PROPN
bjp-23981	20	47	.	.	PUNCT
bjp-23981	21	1	this	this	DET
bjp-23981	21	2	work	work	NOUN
bjp-23981	21	3	is	be	AUX
bjp-23981	21	4	licensed	license	VERB
bjp-23981	21	5	under	under	ADP
bjp-23981	21	6	a	a	DET
bjp-23981	21	7	creative	creative	ADJ
bjp-23981	21	8	commons	common	NOUN
bjp-23981	21	9	attribution	attribution	NOUN
bjp-23981	21	10	4.0	4.0	NUM
bjp-23981	21	11	international	international	ADJ
bjp-23981	21	12	license	license	NOUN
bjp-23981	21	13	.	.	PUNCT
bjp-23981	22	1	you	you	PRON
bjp-23981	22	2	are	be	AUX
bjp-23981	22	3	free	free	ADJ
bjp-23981	22	4	to	to	PART
bjp-23981	22	5	copy	copy	VERB
bjp-23981	22	6	,	,	PUNCT
bjp-23981	22	7	distribute	distribute	VERB
bjp-23981	22	8	and	and	CCONJ
bjp-23981	22	9	perform	perform	VERB
bjp-23981	22	10	the	the	DET
bjp-23981	22	11	work	work	NOUN
bjp-23981	22	12	.	.	PUNCT
bjp-23981	23	1	you	you	PRON
bjp-23981	23	2	must	must	AUX
bjp-23981	23	3	attribute	attribute	VERB
bjp-23981	23	4	the	the	DET
bjp-23981	23	5	work	work	NOUN
bjp-23981	23	6	in	in	ADP
bjp-23981	23	7	the	the	DET
bjp-23981	23	8	manner	manner	NOUN
bjp-23981	23	9	specified	specify	VERB
bjp-23981	23	10	by	by	ADP
bjp-23981	23	11	the	the	DET
bjp-23981	23	12	author	author	NOUN
bjp-23981	23	13	or	or	CCONJ
bjp-23981	23	14	licensor	licensor	VERB
bjp-23981	23	15	the	the	DET
bjp-23981	23	16	management	management	NOUN
bjp-23981	23	17	of	of	ADP
bjp-23981	23	18	arterial	arterial	ADJ
bjp-23981	23	19	thromboembolism	thromboembolism	NOUN
bjp-23981	23	20	.	.	PUNCT
bjp-23981	24	1	the	the	DET
bjp-23981	24	2	tpa	tpa	PROPN
bjp-23981	24	3	like	like	ADP
bjp-23981	24	4	streptokinase	streptokinase	PROPN
bjp-23981	24	5	and	and	CCONJ
bjp-23981	24	6	urokinase	urokinase	NOUN
bjp-23981	24	7	which	which	PRON
bjp-23981	24	8	are	be	AUX
bjp-23981	24	9	widely	widely	ADV
bjp-23981	24	10	used	use	VERB
bjp-23981	24	11	as	as	ADP
bjp-23981	24	12	thrombolytic	thrombolytic	ADJ
bjp-23981	24	13	drugs	drug	NOUN
bjp-23981	24	14	have	have	AUX
bjp-23981	24	15	marked	mark	VERB
bjp-23981	24	16	clinical	clinical	ADJ
bjp-23981	24	17	drawback	drawback	NOUN
bjp-23981	24	18	.	.	PUNCT
bjp-23981	25	1	these	these	DET
bjp-23981	25	2	agents	agent	NOUN
bjp-23981	25	3	have	have	VERB
bjp-23981	25	4	a	a	DET
bjp-23981	25	5	narrow	narrow	ADJ
bjp-23981	25	6	therapeutic	therapeutic	ADJ
bjp-23981	25	7	index	index	NOUN
bjp-23981	25	8	and	and	CCONJ
bjp-23981	25	9	require	require	VERB
bjp-23981	25	10	continuous	continuous	ADJ
bjp-23981	25	11	monitoring	monitoring	NOUN
bjp-23981	25	12	.	.	PUNCT
bjp-23981	26	1	also	also	ADV
bjp-23981	26	2	,	,	PUNCT
bjp-23981	26	3	these	these	DET
bjp-23981	26	4	agents	agent	NOUN
bjp-23981	26	5	have	have	VERB
bjp-23981	26	6	significant	significant	ADJ
bjp-23981	26	7	risk	risk	NOUN
bjp-23981	26	8	of	of	ADP
bjp-23981	26	9	hemorrhage	hemorrhage	NOUN
bjp-23981	26	10	,	,	PUNCT
bjp-23981	26	11	and	and	CCONJ
bjp-23981	26	12	produce	produce	VERB
bjp-23981	26	13	anaphylactic	anaphylactic	ADJ
bjp-23981	26	14	reaction	reaction	NOUN
bjp-23981	26	15	and	and	CCONJ
bjp-23981	26	16	lacks	lack	VERB
bjp-23981	26	17	specificity	specificity	NOUN
bjp-23981	26	18	.	.	PUNCT
bjp-23981	27	1	these	these	DET
bjp-23981	27	2	entire	entire	ADJ
bjp-23981	27	3	therapeutic	therapeutic	ADJ
bjp-23981	27	4	shortcomings	shortcoming	NOUN
bjp-23981	27	5	of	of	ADP
bjp-23981	27	6	presently	presently	ADV
bjp-23981	27	7	available	available	ADJ
bjp-23981	27	8	streptokinase	streptokinase	PROPN
bjp-23981	27	9	and	and	CCONJ
bjp-23981	27	10	urokinase	urokinase	NOUN
bjp-23981	27	11	and	and	CCONJ
bjp-23981	27	12	other	other	ADJ
bjp-23981	27	13	t	t	PROPN
bjp-23981	27	14	-	-	PUNCT
bjp-23981	27	15	pa	pa	PROPN
bjp-23981	27	16	indicate	indicate	VERB
bjp-23981	27	17	the	the	DET
bjp-23981	27	18	need	need	NOUN
bjp-23981	27	19	for	for	ADP
bjp-23981	27	20	better	well	ADJ
bjp-23981	27	21	thrombolytic	thrombolytic	ADJ
bjp-23981	27	22	agents	agent	NOUN
bjp-23981	27	23	with	with	ADP
bjp-23981	27	24	clinical	clinical	ADJ
bjp-23981	27	25	advantage	advantage	NOUN
bjp-23981	27	26	(	(	PUNCT
bjp-23981	27	27	sobel	sobel	NOUN
bjp-23981	27	28	,	,	PUNCT
bjp-23981	27	29	1984	1984	NUM
bjp-23981	27	30	)	)	PUNCT
bjp-23981	27	31	.	.	PUNCT
bjp-23981	28	1	in	in	ADP
bjp-23981	28	2	the	the	DET
bjp-23981	28	3	previous	previous	ADJ
bjp-23981	28	4	study	study	NOUN
bjp-23981	28	5	,	,	PUNCT
bjp-23981	28	6	we	we	PRON
bjp-23981	28	7	had	have	AUX
bjp-23981	28	8	reported	report	VERB
bjp-23981	28	9	the	the	DET
bjp-23981	28	10	synthesis	synthesis	NOUN
bjp-23981	28	11	and	and	CCONJ
bjp-23981	28	12	characterization	characterization	NOUN
bjp-23981	28	13	of	of	ADP
bjp-23981	28	14	1,3,4	1,3,4	NUM
bjp-23981	28	15	-	-	PUNCT
bjp-23981	28	16	oxadiaozle	oxadiaozle	NOUN
bjp-23981	28	17	derivatives	derivative	NOUN
bjp-23981	28	18	derived	derive	VERB
bjp-23981	28	19	from	from	ADP
bjp-23981	28	20	benzimidazole	benzimidazole	PROPN
bjp-23981	28	21	4a-4k	4a-4k	PUNCT
bjp-23981	29	1	(	(	PUNCT
bjp-23981	29	2	figure	figure	NOUN
bjp-23981	29	3	1	1	NUM
bjp-23981	29	4	)	)	PUNCT
bjp-23981	29	5	,	,	PUNCT
bjp-23981	29	6	from	from	ADP
bjp-23981	29	7	(	(	PUNCT
bjp-23981	29	8	1hbenzo	1hbenzo	NUM
bjp-23981	29	9	[	[	X
bjp-23981	29	10	d	d	X
bjp-23981	29	11	]	]	X
bjp-23981	29	12	imidazol-2	imidazol-2	NUM
bjp-23981	29	13	-	-	PUNCT
bjp-23981	29	14	yl	yl	NOUN
bjp-23981	29	15	)	)	PUNCT
bjp-23981	29	16	methanamine	methanamine	NOUN
bjp-23981	29	17	(	(	PUNCT
bjp-23981	29	18	vishwanathan	vishwanathan	NOUN
bjp-23981	29	19	and	and	CCONJ
bjp-23981	29	20	gurupadayya	gurupadayya	PROPN
bjp-23981	29	21	,	,	PUNCT
bjp-23981	29	22	2014	2014	NUM
bjp-23981	29	23	)	)	PUNCT
bjp-23981	29	24	.	.	PUNCT
bjp-23981	30	1	the	the	DET
bjp-23981	30	2	1,3,4	1,3,4	NUM
bjp-23981	30	3	-	-	PUNCT
bjp-23981	30	4	oxadiazoles	oxadiazole	NOUN
bjp-23981	30	5	;	;	PUNCT
bjp-23981	30	6	n-[(1hbenzo	n-[(1hbenzo	X
bjp-23981	31	1	[	[	X
bjp-23981	31	2	d	d	X
bjp-23981	31	3	]	]	X
bjp-23981	31	4	imidazol-2	imidazol-2	NUM
bjp-23981	31	5	-	-	PUNCT
bjp-23981	31	6	yl	yl	NOUN
bjp-23981	31	7	)	)	PUNCT
bjp-23981	31	8	methyl	methyl	NOUN
bjp-23981	31	9	]	]	X
bjp-23981	31	10	(	(	PUNCT
bjp-23981	31	11	5	5	NUM
bjp-23981	31	12	-	-	PUNCT
bjp-23981	31	13	substituted-1,3,4oxadiazol-2	substituted-1,3,4oxadiazol-2	NOUN
bjp-23981	31	14	-	-	PUNCT
bjp-23981	31	15	yl	yl	NOUN
bjp-23981	31	16	)	)	PUNCT
bjp-23981	31	17	methanamine	methanamine	NOUN
bjp-23981	31	18	(	(	PUNCT
bjp-23981	31	19	4a-4j	4a-4j	NOUN
bjp-23981	31	20	)	)	PUNCT
bjp-23981	31	21	were	be	AUX
bjp-23981	31	22	prepared	prepare	VERB
bjp-23981	31	23	from	from	ADP
bjp-23981	31	24	nucleophilic	nucleophilic	ADJ
bjp-23981	31	25	addition	addition	NOUN
bjp-23981	31	26	of	of	ADP
bjp-23981	31	27	aryl	aryl	NOUN
bjp-23981	31	28	/	/	SYM
bjp-23981	31	29	heteroaryl	heteroaryl	NOUN
bjp-23981	31	30	/	/	SYM
bjp-23981	31	31	aliphatic	aliphatic	ADJ
bjp-23981	31	32	carboxylic	carboxylic	ADJ
bjp-23981	31	33	acids	acid	NOUN
bjp-23981	31	34	with	with	ADP
bjp-23981	31	35	to	to	PART
bjp-23981	31	36	yield	yield	VERB
bjp-23981	31	37	2-[(1h	2-[(1h	NUM
bjp-23981	31	38	-	-	PUNCT
bjp-23981	31	39	benzo	benzo	NOUN
bjp-23981	31	40	[	[	X
bjp-23981	31	41	d	d	X
bjp-23981	31	42	]	]	X
bjp-23981	31	43	imidazol	imidazol	ADJ
bjp-23981	31	44	-2	-2	NOUN
bjp-23981	31	45	-	-	PUNCT
bjp-23981	31	46	yl	yl	NOUN
bjp-23981	31	47	)	)	PUNCT
bjp-23981	31	48	methylamino	methylamino	NOUN
bjp-23981	31	49	]	]	PUNCT
bjp-23981	31	50	acetohydrazide	acetohydrazide	ADP
bjp-23981	31	51	in	in	ADP
bjp-23981	31	52	presence	presence	NOUN
bjp-23981	31	53	of	of	ADP
bjp-23981	31	54	phosphorous	phosphorous	ADJ
bjp-23981	31	55	oxychloride	oxychloride	NOUN
bjp-23981	31	56	.	.	PUNCT
bjp-23981	32	1	the	the	DET
bjp-23981	32	2	acetohydrazide	acetohydrazide	ADJ
bjp-23981	32	3	derivative	derivative	NOUN
bjp-23981	32	4	was	be	AUX
bjp-23981	32	5	prepared	prepare	VERB
bjp-23981	32	6	by	by	ADP
bjp-23981	32	7	condensation	condensation	NOUN
bjp-23981	32	8	of	of	ADP
bjp-23981	32	9	ethyl	ethyl	PROPN
bjp-23981	32	10	2-[(1hbenzo	2-[(1hbenzo	NUM
bjp-23981	33	1	[	[	X
bjp-23981	33	2	d	d	X
bjp-23981	33	3	]	]	X
bjp-23981	33	4	imidazol-2	imidazol-2	NUM
bjp-23981	33	5	-	-	PUNCT
bjp-23981	33	6	yl)methylamino]acetate	yl)methylamino]acetate	NOUN
bjp-23981	33	7	with	with	ADP
bjp-23981	33	8	hydrazine	hydrazine	NOUN
bjp-23981	33	9	monohydrate	monohydrate	NOUN
bjp-23981	33	10	.	.	PUNCT
bjp-23981	34	1	the	the	DET
bjp-23981	34	2	ester	ester	NOUN
bjp-23981	34	3	derivative	derivative	NOUN
bjp-23981	34	4	was	be	AUX
bjp-23981	34	5	prepared	prepare	VERB
bjp-23981	34	6	by	by	ADP
bjp-23981	34	7	condensation	condensation	NOUN
bjp-23981	34	8	of	of	ADP
bjp-23981	34	9	the	the	DET
bjp-23981	34	10	starting	starting	NOUN
bjp-23981	34	11	material	material	NOUN
bjp-23981	34	12	(	(	PUNCT
bjp-23981	34	13	1hbenzo	1hbenzo	NUM
bjp-23981	34	14	[	[	X
bjp-23981	34	15	d	d	X
bjp-23981	34	16	]	]	X
bjp-23981	34	17	imidazol-2	imidazol-2	NUM
bjp-23981	34	18	-	-	PUNCT
bjp-23981	34	19	yl	yl	NOUN
bjp-23981	34	20	)	)	PUNCT
bjp-23981	34	21	methanamine	methanamine	NOUN
bjp-23981	34	22	with	with	ADP
bjp-23981	34	23	ethyl	ethyl	PROPN
bjp-23981	34	24	2chloroacetate	2chloroacetate	NUM
bjp-23981	34	25	in	in	ADP
bjp-23981	34	26	the	the	DET
bjp-23981	34	27	presence	presence	NOUN
bjp-23981	34	28	of	of	ADP
bjp-23981	34	29	anhydrous	anhydrous	ADJ
bjp-23981	34	30	potassium	potassium	NOUN
bjp-23981	34	31	carbonate	carbonate	NOUN
bjp-23981	34	32	.	.	PUNCT
bjp-23981	35	1	the	the	DET
bjp-23981	35	2	starting	start	VERB
bjp-23981	35	3	material	material	NOUN
bjp-23981	35	4	(	(	PUNCT
bjp-23981	35	5	1h	1h	NUM
bjp-23981	35	6	-	-	PUNCT
bjp-23981	35	7	benzo	benzo	NOUN
bjp-23981	35	8	[	[	X
bjp-23981	35	9	d]imidazol2	d]imidazol2	ADJ
bjp-23981	35	10	-	-	PUNCT
bjp-23981	35	11	yl	yl	NOUN
bjp-23981	35	12	)	)	PUNCT
bjp-23981	35	13	methanamine	methanamine	NOUN
bjp-23981	35	14	was	be	AUX
bjp-23981	35	15	synthesized	synthesize	VERB
bjp-23981	35	16	by	by	ADP
bjp-23981	35	17	nucleophilic	nucleophilic	ADJ
bjp-23981	35	18	addition	addition	NOUN
bjp-23981	35	19	of	of	ADP
bjp-23981	35	20	benzene-1,2	benzene-1,2	NOUN
bjp-23981	35	21	-	-	PUNCT
bjp-23981	35	22	diamine	diamine	NOUN
bjp-23981	35	23	with	with	ADP
bjp-23981	35	24	glycine	glycine	NOUN
bjp-23981	35	25	in	in	ADP
bjp-23981	35	26	the	the	DET
bjp-23981	35	27	presence	presence	NOUN
bjp-23981	35	28	of	of	ADP
bjp-23981	35	29	hydrochloric	hydrochloric	ADJ
bjp-23981	35	30	acid	acid	NOUN
bjp-23981	35	31	.	.	PUNCT
bjp-23981	36	1	the	the	DET
bjp-23981	36	2	compound	compound	NOUN
bjp-23981	36	3	5-{[(1hbenzo[d]imidazol-2	5-{[(1hbenzo[d]imidazol-2	ADV
bjp-23981	36	4	-	-	PUNCT
bjp-23981	36	5	yl)methylamino]methyl}-1,3,4oxadiazole-2	yl)methylamino]methyl}-1,3,4oxadiazole-2	ADJ
bjp-23981	36	6	-	-	NOUN
bjp-23981	36	7	thiol	thiol	NOUN
bjp-23981	36	8	(	(	PUNCT
bjp-23981	36	9	4k	4k	NOUN
bjp-23981	36	10	)	)	PUNCT
bjp-23981	36	11	was	be	AUX
bjp-23981	36	12	prepared	prepare	VERB
bjp-23981	36	13	by	by	ADP
bjp-23981	36	14	condensation	condensation	NOUN
bjp-23981	36	15	of	of	ADP
bjp-23981	36	16	the	the	DET
bjp-23981	36	17	acetohydrazide	acetohydrazide	ADJ
bjp-23981	36	18	derivative	derivative	NOUN
bjp-23981	36	19	with	with	ADP
bjp-23981	36	20	carbon	carbon	NOUN
bjp-23981	36	21	disulfide	disulfide	NOUN
bjp-23981	36	22	and	and	CCONJ
bjp-23981	36	23	potassium	potassium	NOUN
bjp-23981	36	24	hydroxide	hydroxide	NOUN
bjp-23981	36	25	.	.	PUNCT
bjp-23981	37	1	in	in	ADP
bjp-23981	37	2	continuation	continuation	NOUN
bjp-23981	37	3	of	of	ADP
bjp-23981	37	4	the	the	DET
bjp-23981	37	5	work	work	NOUN
bjp-23981	37	6	,	,	PUNCT
bjp-23981	37	7	in	in	ADP
bjp-23981	37	8	the	the	DET
bjp-23981	37	9	present	present	ADJ
bjp-23981	37	10	investigation	investigation	NOUN
bjp-23981	37	11	,	,	PUNCT
bjp-23981	37	12	we	we	PRON
bjp-23981	37	13	herein	herein	VERB
bjp-23981	37	14	report	report	VERB
bjp-23981	37	15	the	the	DET
bjp-23981	37	16	in	in	ADP
bjp-23981	37	17	silico	silico	NOUN
bjp-23981	37	18	adme	adme	VERB
bjp-23981	37	19	studies	study	NOUN
bjp-23981	37	20	,	,	PUNCT
bjp-23981	37	21	molecular	molecular	ADJ
bjp-23981	37	22	docking	docking	NOUN
bjp-23981	37	23	results	result	NOUN
bjp-23981	37	24	of	of	ADP
bjp-23981	37	25	the	the	DET
bjp-23981	37	26	synthesized	synthesize	VERB
bjp-23981	37	27	compounds	compound	NOUN
bjp-23981	37	28	onto	onto	ADP
bjp-23981	37	29	factor	factor	NOUN
bjp-23981	37	30	xa	xa	PROPN
bjp-23981	37	31	(	(	PUNCT
bjp-23981	37	32	1nfy	1nfy	PROPN
bjp-23981	37	33	)	)	PUNCT
bjp-23981	37	34	in	in	ADP
bjp-23981	37	35	order	order	NOUN
bjp-23981	37	36	to	to	PART
bjp-23981	37	37	visualize	visualize	VERB
bjp-23981	37	38	the	the	DET
bjp-23981	37	39	importance	importance	NOUN
bjp-23981	37	40	of	of	ADP
bjp-23981	37	41	possible	possible	ADJ
bjp-23981	37	42	antithrombotic	antithrombotic	ADJ
bjp-23981	37	43	efficacy	efficacy	NOUN
bjp-23981	37	44	and	and	CCONJ
bjp-23981	37	45	the	the	DET
bjp-23981	37	46	in	in	ADV
bjp-23981	37	47	vitro	vitro	X
bjp-23981	37	48	clot	clot	NOUN
bjp-23981	37	49	lysis	lysis	NOUN
bjp-23981	37	50	efficacy	efficacy	NOUN
bjp-23981	37	51	of	of	ADP
bjp-23981	37	52	these	these	DET
bjp-23981	37	53	eleven	eleven	NUM
bjp-23981	37	54	1,3,4oxadiazole	1,3,4oxadiazole	NUM
bjp-23981	37	55	derivatives	derivative	NOUN
bjp-23981	37	56	4a-4k	4a-4k	X
bjp-23981	38	1	(	(	PUNCT
bjp-23981	38	2	table	table	NOUN
bjp-23981	38	3	i	i	NOUN
bjp-23981	38	4	)	)	PUNCT
bjp-23981	38	5	.	.	PUNCT
bjp-23981	39	1	materials	material	NOUN
bjp-23981	39	2	and	and	CCONJ
bjp-23981	39	3	methods	method	NOUN
bjp-23981	39	4	in	in	ADP
bjp-23981	39	5	silico	silico	NOUN
bjp-23981	39	6	adme	adme	VERB
bjp-23981	39	7	studies	study	VERB
bjp-23981	39	8	a	a	DET
bjp-23981	39	9	computational	computational	ADJ
bjp-23981	39	10	study	study	NOUN
bjp-23981	39	11	for	for	ADP
bjp-23981	39	12	prediction	prediction	NOUN
bjp-23981	39	13	of	of	ADP
bjp-23981	39	14	adme	adme	NOUN
bjp-23981	39	15	properties	property	NOUN
bjp-23981	39	16	of	of	ADP
bjp-23981	39	17	the	the	DET
bjp-23981	39	18	molecules	molecule	NOUN
bjp-23981	39	19	was	be	AUX
bjp-23981	39	20	performed	perform	VERB
bjp-23981	39	21	by	by	ADP
bjp-23981	39	22	determination	determination	NOUN
bjp-23981	39	23	of	of	ADP
bjp-23981	39	24	lipophilicity	lipophilicity	NOUN
bjp-23981	39	25	,	,	PUNCT
bjp-23981	39	26	topological	topological	ADJ
bjp-23981	39	27	polar	polar	ADJ
bjp-23981	39	28	surface	surface	NOUN
bjp-23981	39	29	68	68	NUM
bjp-23981	39	30	bangladesh	bangladesh	NOUN
bjp-23981	39	31	j	j	PROPN
bjp-23981	39	32	pharmacol	pharmacol	PROPN
bjp-23981	39	33	2016	2016	NUM
bjp-23981	39	34	;	;	PUNCT
bjp-23981	39	35	11	11	NUM
bjp-23981	39	36	:	:	SYM
bjp-23981	39	37	67	67	NUM
bjp-23981	39	38	-	-	SYM
bjp-23981	39	39	74	74	NUM
bjp-23981	39	40	4a	4a	NOUN
bjp-23981	39	41	c6h5	c6h5	PROPN
bjp-23981	39	42	4b	4b	PROPN
bjp-23981	39	43	2	2	PROPN
bjp-23981	39	44	-	-	PUNCT
bjp-23981	39	45	no2c6h4	no2c6h4	PROPN
bjp-23981	39	46	4c	4c	NUM
bjp-23981	39	47	3,5	3,5	NUM
bjp-23981	39	48	-(no2)2c6h3	-(no2)2c6h3	NOUN
bjp-23981	39	49	4d	4d	ADJ
bjp-23981	39	50	4	4	NUM
bjp-23981	39	51	-	-	PUNCT
bjp-23981	39	52	nh2c6h4	nh2c6h4	NOUN
bjp-23981	39	53	4e	4e	NOUN
bjp-23981	39	54	2	2	NUM
bjp-23981	39	55	-	-	PUNCT
bjp-23981	39	56	nh2c6h4	nh2c6h4	NOUN
bjp-23981	39	57	4f	4f	NUM
bjp-23981	39	58	ohc6h4	ohc6h4	NOUN
bjp-23981	40	1	4	4	NUM
bjp-23981	40	2	g	g	NOUN
bjp-23981	40	3	2	2	NUM
bjp-23981	40	4	-ohc6h	-ohc6h	NOUN
bjp-23981	40	5	4h	4h	NUM
bjp-23981	40	6	h	h	PROPN
bjp-23981	40	7	4i	4i	PROPN
bjp-23981	40	8	ch3	ch3	PROPN
bjp-23981	40	9	4j	4j	NOUN
bjp-23981	40	10	c5h4n	c5h4n	X
bjp-23981	40	11	4k	4k	NOUN
bjp-23981	40	12	sh	sh	NOUN
bjp-23981	40	13	r	r	NOUN
bjp-23981	40	14	=	=	NOUN
bjp-23981	40	15	figure	figure	NOUN
bjp-23981	40	16	1	1	NUM
bjp-23981	40	17	:	:	PUNCT
bjp-23981	40	18	synthesized	synthesize	VERB
bjp-23981	40	19	1,3,4	1,3,4	NUM
bjp-23981	40	20	-	-	PUNCT
bjp-23981	40	21	oxadiazole	oxadiazole	NOUN
bjp-23981	40	22	derivative	derivative	NOUN
bjp-23981	40	23	from	from	ADP
bjp-23981	40	24	benzimidazole	benzimidazole	PROPN
bjp-23981	40	25	4a-4k	4a-4k	NUM
bjp-23981	40	26	table	table	NOUN
bjp-23981	40	27	i	i	PRON
bjp-23981	40	28	synthesized	synthesize	VERB
bjp-23981	40	29	1,3,4	1,3,4	NUM
bjp-23981	40	30	-	-	PUNCT
bjp-23981	40	31	oxadiazole	oxadiazole	NOUN
bjp-23981	40	32	derivatives	derivative	NOUN
bjp-23981	40	33	from	from	ADP
bjp-23981	40	34	benzimidazole	benzimidazole	PROPN
bjp-23981	40	35	4a-4k	4a-4k	X
bjp-23981	41	1	sl	sl	INTJ
bjp-23981	41	2	.	.	PUNCT
bjp-23981	41	3	no	no	INTJ
bjp-23981	41	4	.	.	PUNCT
bjp-23981	42	1	compound	compound	NOUN
bjp-23981	42	2	compound	compound	NOUN
bjp-23981	42	3	1	1	NUM
bjp-23981	42	4	(	(	PUNCT
bjp-23981	42	5	1h	1h	NUM
bjp-23981	42	6	-	-	PUNCT
bjp-23981	42	7	benzo	benzo	NOUN
bjp-23981	43	1	[	[	X
bjp-23981	43	2	d	d	X
bjp-23981	43	3	]	]	X
bjp-23981	43	4	imidazol-2	imidazol-2	NUM
bjp-23981	43	5	-	-	PUNCT
bjp-23981	43	6	yl)-n-	yl)-n-	NOUN
bjp-23981	43	7	{	{	PUNCT
bjp-23981	43	8	(	(	PUNCT
bjp-23981	43	9	5	5	NUM
bjp-23981	43	10	-	-	PUNCT
bjp-23981	43	11	phenyl-1,3,4	phenyl-1,3,4	ADJ
bjp-23981	43	12	-	-	PUNCT
bjp-23981	43	13	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	43	14	-	-	PUNCT
bjp-23981	43	15	yl	yl	NOUN
bjp-23981	43	16	)	)	PUNCT
bjp-23981	43	17	methyl	methyl	NOUN
bjp-23981	43	18	}	}	PUNCT
bjp-23981	43	19	methanamine	methanamine	NOUN
bjp-23981	43	20	4a	4a	NUM
bjp-23981	43	21	2	2	NUM
bjp-23981	43	22	(	(	PUNCT
bjp-23981	43	23	1h	1h	NUM
bjp-23981	43	24	-	-	PUNCT
bjp-23981	43	25	benzo	benzo	NOUN
bjp-23981	44	1	[	[	X
bjp-23981	44	2	d	d	X
bjp-23981	44	3	]	]	X
bjp-23981	44	4	imidazol-2	imidazol-2	NUM
bjp-23981	44	5	-	-	PUNCT
bjp-23981	44	6	yl	yl	NOUN
bjp-23981	44	7	)	)	PUNCT
bjp-23981	44	8	-n-	-n-	PROPN
bjp-23981	44	9	[	[	PUNCT
bjp-23981	44	10	{	{	PUNCT
bjp-23981	44	11	5-(2	5-(2	NOUN
bjp-23981	44	12	-	-	PUNCT
bjp-23981	44	13	nitrophenyl)-1,3,4	nitrophenyl)-1,3,4	ADJ
bjp-23981	44	14	-	-	PUNCT
bjp-23981	44	15	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	44	16	-	-	PUNCT
bjp-23981	44	17	yl	yl	NOUN
bjp-23981	44	18	}	}	PUNCT
bjp-23981	44	19	methyl	methyl	NOUN
bjp-23981	44	20	]	]	PUNCT
bjp-23981	44	21	methanamine	methanamine	NOUN
bjp-23981	44	22	4b	4b	PROPN
bjp-23981	44	23	3	3	NUM
bjp-23981	44	24	(	(	PUNCT
bjp-23981	44	25	1h	1h	NUM
bjp-23981	44	26	-	-	PUNCT
bjp-23981	44	27	benzo	benzo	NOUN
bjp-23981	44	28	[	[	X
bjp-23981	44	29	d	d	X
bjp-23981	44	30	]	]	X
bjp-23981	44	31	imidazol-2	imidazol-2	NUM
bjp-23981	44	32	-	-	PUNCT
bjp-23981	44	33	yl)-n-	yl)-n-	NOUN
bjp-23981	44	34	[	[	PUNCT
bjp-23981	44	35	{	{	PUNCT
bjp-23981	44	36	5-(3,5	5-(3,5	NUM
bjp-23981	44	37	-	-	PUNCT
bjp-23981	44	38	dinitrophenyl)-1,3,4	dinitrophenyl)-1,3,4	ADV
bjp-23981	44	39	-	-	PUNCT
bjp-23981	44	40	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	44	41	-	-	PUNCT
bjp-23981	44	42	yl	yl	NOUN
bjp-23981	44	43	}	}	PUNCT
bjp-23981	44	44	methyl	methyl	NOUN
bjp-23981	44	45	]	]	PUNCT
bjp-23981	44	46	methanamine	methanamine	NOUN
bjp-23981	44	47	4c	4c	NUM
bjp-23981	44	48	4	4	NUM
bjp-23981	44	49	4-(5-	4-(5-	NUM
bjp-23981	44	50	[	[	PUNCT
bjp-23981	44	51	{	{	PUNCT
bjp-23981	44	52	(	(	PUNCT
bjp-23981	44	53	1h	1h	NUM
bjp-23981	44	54	-	-	PUNCT
bjp-23981	44	55	benzo[d]imidazol-2	benzo[d]imidazol-2	NOUN
bjp-23981	44	56	-	-	PUNCT
bjp-23981	44	57	yl	yl	NOUN
bjp-23981	44	58	)	)	PUNCT
bjp-23981	44	59	methylamino}methyl]-1,3,4	methylamino}methyl]-1,3,4	ADJ
bjp-23981	44	60	-	-	PUNCT
bjp-23981	44	61	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	44	62	-	-	PUNCT
bjp-23981	44	63	yl	yl	NOUN
bjp-23981	44	64	)	)	PUNCT
bjp-23981	44	65	benzenamine	benzenamine	NOUN
bjp-23981	44	66	4d	4d	NOUN
bjp-23981	44	67	5	5	NUM
bjp-23981	44	68	2-(5-	2-(5-	NUM
bjp-23981	44	69	[	[	PUNCT
bjp-23981	44	70	{	{	PUNCT
bjp-23981	44	71	(	(	PUNCT
bjp-23981	44	72	1h	1h	NUM
bjp-23981	44	73	-	-	PUNCT
bjp-23981	44	74	benzo[d]imidazol-2	benzo[d]imidazol-2	NOUN
bjp-23981	44	75	-	-	PUNCT
bjp-23981	44	76	yl	yl	NOUN
bjp-23981	44	77	)	)	PUNCT
bjp-23981	44	78	methylamino}methyl]-1,3,4	methylamino}methyl]-1,3,4	ADJ
bjp-23981	44	79	-	-	PUNCT
bjp-23981	44	80	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	44	81	-	-	PUNCT
bjp-23981	44	82	yl	yl	NOUN
bjp-23981	44	83	)	)	PUNCT
bjp-23981	44	84	benzenamine	benzenamine	NOUN
bjp-23981	44	85	4e	4e	NOUN
bjp-23981	44	86	6	6	NUM
bjp-23981	44	87	4-(5-	4-(5-	NUM
bjp-23981	44	88	[	[	PUNCT
bjp-23981	44	89	{	{	PUNCT
bjp-23981	44	90	(	(	PUNCT
bjp-23981	44	91	1h	1h	NUM
bjp-23981	44	92	-	-	PUNCT
bjp-23981	44	93	benzo[d]imidazol-2	benzo[d]imidazol-2	NOUN
bjp-23981	44	94	-	-	PUNCT
bjp-23981	44	95	yl	yl	NOUN
bjp-23981	44	96	)	)	PUNCT
bjp-23981	44	97	methylamino}methyl]-1,3,4	methylamino}methyl]-1,3,4	ADJ
bjp-23981	44	98	-	-	PUNCT
bjp-23981	44	99	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	44	100	-	-	PUNCT
bjp-23981	44	101	yl	yl	NOUN
bjp-23981	44	102	)	)	PUNCT
bjp-23981	44	103	phenol	phenol	NOUN
bjp-23981	44	104	4f	4f	NUM
bjp-23981	44	105	7	7	NUM
bjp-23981	44	106	2-(5-	2-(5-	NUM
bjp-23981	44	107	[	[	PUNCT
bjp-23981	44	108	{	{	PUNCT
bjp-23981	44	109	(	(	PUNCT
bjp-23981	44	110	1h	1h	NUM
bjp-23981	44	111	-	-	PUNCT
bjp-23981	44	112	benzo[d]imidazol-2	benzo[d]imidazol-2	NOUN
bjp-23981	44	113	-	-	PUNCT
bjp-23981	44	114	yl	yl	NOUN
bjp-23981	44	115	)	)	PUNCT
bjp-23981	44	116	methylamino}methyl]-1,3,4	methylamino}methyl]-1,3,4	ADJ
bjp-23981	44	117	-	-	PUNCT
bjp-23981	44	118	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	44	119	-	-	PUNCT
bjp-23981	44	120	yl	yl	NOUN
bjp-23981	44	121	)	)	PUNCT
bjp-23981	44	122	phenol	phenol	NOUN
bjp-23981	44	123	4	4	NUM
bjp-23981	44	124	g	g	NOUN
bjp-23981	44	125	8	8	NUM
bjp-23981	44	126	n-	n-	SYM
bjp-23981	45	1	[	[	PUNCT
bjp-23981	45	2	(	(	PUNCT
bjp-23981	45	3	1,3,4	1,3,4	NUM
bjp-23981	45	4	-	-	PUNCT
bjp-23981	45	5	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	45	6	-	-	PUNCT
bjp-23981	45	7	yl	yl	NOUN
bjp-23981	45	8	)	)	PUNCT
bjp-23981	45	9	methyl	methyl	NOUN
bjp-23981	45	10	]	]	X
bjp-23981	45	11	(	(	PUNCT
bjp-23981	45	12	1h	1h	NUM
bjp-23981	45	13	-	-	PUNCT
bjp-23981	45	14	benzo	benzo	NOUN
bjp-23981	45	15	[	[	X
bjp-23981	45	16	d	d	X
bjp-23981	45	17	]	]	X
bjp-23981	45	18	imidazol-2	imidazol-2	NUM
bjp-23981	45	19	-	-	PUNCT
bjp-23981	45	20	yl	yl	NOUN
bjp-23981	45	21	)	)	PUNCT
bjp-23981	45	22	methanamine	methanamine	NOUN
bjp-23981	45	23	4h	4h	NUM
bjp-23981	45	24	9	9	NUM
bjp-23981	45	25	(	(	PUNCT
bjp-23981	45	26	1h	1h	NUM
bjp-23981	45	27	-	-	PUNCT
bjp-23981	45	28	benzo	benzo	NOUN
bjp-23981	46	1	[	[	X
bjp-23981	46	2	d	d	X
bjp-23981	46	3	]	]	X
bjp-23981	46	4	imidazol-2	imidazol-2	NUM
bjp-23981	46	5	-	-	PUNCT
bjp-23981	46	6	yl)-n-	yl)-n-	NOUN
bjp-23981	46	7	[	[	PUNCT
bjp-23981	46	8	(	(	PUNCT
bjp-23981	46	9	5	5	NUM
bjp-23981	46	10	-	-	PUNCT
bjp-23981	46	11	methyl-1,3,4	methyl-1,3,4	ADP
bjp-23981	46	12	-	-	PUNCT
bjp-23981	46	13	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	46	14	-	-	PUNCT
bjp-23981	46	15	yl	yl	NOUN
bjp-23981	46	16	)	)	PUNCT
bjp-23981	46	17	methyl	methyl	NOUN
bjp-23981	46	18	]	]	PUNCT
bjp-23981	46	19	methanamine	methanamine	NOUN
bjp-23981	46	20	4i	4i	NUM
bjp-23981	46	21	10	10	NUM
bjp-23981	46	22	(	(	PUNCT
bjp-23981	46	23	1h	1h	NUM
bjp-23981	46	24	-	-	PUNCT
bjp-23981	46	25	benzo	benzo	NOUN
bjp-23981	47	1	[	[	X
bjp-23981	47	2	d	d	X
bjp-23981	47	3	]	]	X
bjp-23981	47	4	imidazol-2	imidazol-2	NUM
bjp-23981	47	5	-	-	PUNCT
bjp-23981	47	6	yl)-n-	yl)-n-	NOUN
bjp-23981	47	7	[	[	PUNCT
bjp-23981	47	8	{	{	PUNCT
bjp-23981	47	9	5-(pyridin-3	5-(pyridin-3	NUM
bjp-23981	47	10	-	-	NOUN
bjp-23981	47	11	yl)-1,3,4	yl)-1,3,4	ADJ
bjp-23981	47	12	-	-	PUNCT
bjp-23981	47	13	oxadiazol-2	oxadiazol-2	NUM
bjp-23981	47	14	-	-	PUNCT
bjp-23981	47	15	yl	yl	NOUN
bjp-23981	47	16	}	}	PUNCT
bjp-23981	47	17	methyl	methyl	NOUN
bjp-23981	47	18	]	]	PUNCT
bjp-23981	47	19	methanamine	methanamine	NOUN
bjp-23981	47	20	4j	4j	VERB
bjp-23981	48	1	11	11	NUM
bjp-23981	48	2	5-	5-	NUM
bjp-23981	48	3	[	[	PUNCT
bjp-23981	48	4	{	{	PUNCT
bjp-23981	48	5	(	(	PUNCT
bjp-23981	48	6	1h	1h	NUM
bjp-23981	48	7	-	-	PUNCT
bjp-23981	48	8	benzo	benzo	NOUN
bjp-23981	48	9	[	[	X
bjp-23981	48	10	d	d	X
bjp-23981	48	11	]	]	X
bjp-23981	48	12	imidazol-2	imidazol-2	NUM
bjp-23981	48	13	-	-	PUNCT
bjp-23981	48	14	yl	yl	NOUN
bjp-23981	48	15	)	)	PUNCT
bjp-23981	48	16	methylamino	methylamino	NOUN
bjp-23981	48	17	}	}	PUNCT
bjp-23981	48	18	methyl]-1,3,4	methyl]-1,3,4	PROPN
bjp-23981	48	19	-	-	PUNCT
bjp-23981	48	20	oxadiazole-2	oxadiazole-2	NUM
bjp-23981	48	21	-	-	PUNCT
bjp-23981	48	22	thiol	thiol	NOUN
bjp-23981	48	23	4k	4k	NOUN
bjp-23981	48	24	o	o	NOUN
bjp-23981	48	25	n	n	VERB
bjp-23981	48	26	nh	nh	PROPN
bjp-23981	48	27	n	n	CCONJ
bjp-23981	48	28	n	n	ADP
bjp-23981	48	29	h	h	NOUN
bjp-23981	48	30	n	n	CCONJ
bjp-23981	48	31	r	r	NOUN
bjp-23981	48	32	area	area	NOUN
bjp-23981	48	33	(	(	PUNCT
bjp-23981	48	34	tpsa	tpsa	PROPN
bjp-23981	48	35	)	)	PUNCT
bjp-23981	48	36	,	,	PUNCT
bjp-23981	48	37	percentage	percentage	NOUN
bjp-23981	48	38	of	of	ADP
bjp-23981	48	39	absorption	absorption	NOUN
bjp-23981	48	40	(	(	PUNCT
bjp-23981	48	41	%	%	INTJ
bjp-23981	48	42	abs	ab	NOUN
bjp-23981	48	43	)	)	PUNCT
bjp-23981	48	44	,	,	PUNCT
bjp-23981	48	45	the	the	DET
bjp-23981	48	46	drug	drug	NOUN
bjp-23981	48	47	-likeness	-likeness	NOUN
bjp-23981	48	48	and	and	CCONJ
bjp-23981	48	49	drug	drug	NOUN
bjp-23981	48	50	score	score	NOUN
bjp-23981	48	51	(	(	PUNCT
bjp-23981	48	52	representing	represent	VERB
bjp-23981	48	53	the	the	DET
bjp-23981	48	54	combined	combine	VERB
bjp-23981	48	55	physico	physico	NOUN
bjp-23981	48	56	-	-	PUNCT
bjp-23981	48	57	chemical	chemical	NOUN
bjp-23981	48	58	,	,	PUNCT
bjp-23981	48	59	pharmacokinetic	pharmacokinetic	ADJ
bjp-23981	48	60	and	and	CCONJ
bjp-23981	48	61	pharmacodynamic	pharmacodynamic	ADJ
bjp-23981	48	62	effects	effect	NOUN
bjp-23981	48	63	of	of	ADP
bjp-23981	48	64	a	a	DET
bjp-23981	48	65	compound	compound	NOUN
bjp-23981	48	66	)	)	PUNCT
bjp-23981	48	67	for	for	ADP
bjp-23981	48	68	the	the	DET
bjp-23981	48	69	synthesized	synthesize	VERB
bjp-23981	48	70	1,3,4	1,3,4	NUM
bjp-23981	48	71	-	-	PUNCT
bjp-23981	48	72	oxadiazoles	oxadiazole	NOUN
bjp-23981	48	73	in	in	ADP
bjp-23981	48	74	order	order	NOUN
bjp-23981	48	75	to	to	PART
bjp-23981	48	76	verify	verify	VERB
bjp-23981	48	77	that	that	SCONJ
bjp-23981	48	78	these	these	DET
bjp-23981	48	79	compounds	compound	NOUN
bjp-23981	48	80	exhibit	exhibit	VERB
bjp-23981	48	81	good	good	ADJ
bjp-23981	48	82	(	(	PUNCT
bjp-23981	48	83	theoretical	theoretical	ADJ
bjp-23981	48	84	)	)	PUNCT
bjp-23981	48	85	oral	oral	ADJ
bjp-23981	48	86	bioavailability	bioavailability	NOUN
bjp-23981	48	87	potential	potential	NOUN
bjp-23981	48	88	.	.	PUNCT
bjp-23981	49	1	the	the	DET
bjp-23981	49	2	lipophilicity	lipophilicity	NOUN
bjp-23981	49	3	and	and	CCONJ
bjp-23981	49	4	tpsa	tpsa	NOUN
bjp-23981	49	5	were	be	AUX
bjp-23981	49	6	calculated	calculate	VERB
bjp-23981	49	7	using	use	VERB
bjp-23981	49	8	online	online	ADJ
bjp-23981	49	9	software	software	NOUN
bjp-23981	49	10	;	;	PUNCT
bjp-23981	49	11	molinspiration	molinspiration	NOUN
bjp-23981	49	12	online	online	ADJ
bjp-23981	49	13	property	property	NOUN
bjp-23981	49	14	calculation	calculation	NOUN
bjp-23981	49	15	toolkit	toolkit	NOUN
bjp-23981	49	16	(	(	PUNCT
bjp-23981	49	17	http://www.molinspiration.com	http://www.molinspiration.com	X
bjp-23981	49	18	)	)	PUNCT
bjp-23981	49	19	,	,	PUNCT
bjp-23981	49	20	while	while	SCONJ
bjp-23981	49	21	the	the	DET
bjp-23981	49	22	aqueous	aqueous	ADJ
bjp-23981	49	23	solubility	solubility	NOUN
bjp-23981	49	24	,	,	PUNCT
bjp-23981	49	25	drug	drug	NOUN
bjp-23981	49	26	-	-	PUNCT
bjp-23981	49	27	likeness	likeness	NOUN
bjp-23981	49	28	and	and	CCONJ
bjp-23981	49	29	drug	drug	NOUN
bjp-23981	49	30	score	score	NOUN
bjp-23981	49	31	were	be	AUX
bjp-23981	49	32	calculated	calculate	VERB
bjp-23981	49	33	using	use	VERB
bjp-23981	49	34	the	the	DET
bjp-23981	49	35	osiris	osiris	PROPN
bjp-23981	49	36	property	property	NOUN
bjp-23981	49	37	explorer	explorer	PROPN
bjp-23981	49	38	software	software	NOUN
bjp-23981	49	39	.	.	PUNCT
bjp-23981	50	1	for	for	ADP
bjp-23981	50	2	the	the	DET
bjp-23981	50	3	study	study	NOUN
bjp-23981	50	4	of	of	ADP
bjp-23981	50	5	drug	drug	NOUN
bjp-23981	50	6	-	-	PUNCT
bjp-23981	50	7	likeness	likeness	NOUN
bjp-23981	50	8	,	,	PUNCT
bjp-23981	50	9	the	the	DET
bjp-23981	50	10	osiris	osiris	PROPN
bjp-23981	50	11	program	program	NOUN
bjp-23981	50	12	uses	use	VERB
bjp-23981	50	13	a	a	DET
bjp-23981	50	14	list	list	NOUN
bjp-23981	50	15	of	of	ADP
bjp-23981	50	16	5,300	5,300	NUM
bjp-23981	50	17	molecular	molecular	ADJ
bjp-23981	50	18	fragments	fragment	NOUN
bjp-23981	50	19	,	,	PUNCT
bjp-23981	50	20	where	where	SCONJ
bjp-23981	50	21	the	the	DET
bjp-23981	50	22	frequency	frequency	NOUN
bjp-23981	50	23	of	of	ADP
bjp-23981	50	24	occurrence	occurrence	NOUN
bjp-23981	50	25	of	of	ADP
bjp-23981	50	26	each	each	DET
bjp-23981	50	27	fragment	fragment	NOUN
bjp-23981	50	28	is	be	AUX
bjp-23981	50	29	determined	determine	VERB
bjp-23981	50	30	based	base	VERB
bjp-23981	50	31	on	on	ADP
bjp-23981	50	32	a	a	DET
bjp-23981	50	33	collection	collection	NOUN
bjp-23981	50	34	of	of	ADP
bjp-23981	50	35	3,300	3,300	NUM
bjp-23981	50	36	drugs	drug	NOUN
bjp-23981	50	37	and	and	CCONJ
bjp-23981	50	38	15,000	15,000	NUM
bjp-23981	50	39	commercially	commercially	ADV
bjp-23981	50	40	available	available	ADJ
bjp-23981	50	41	chemicals	chemical	NOUN
bjp-23981	50	42	that	that	PRON
bjp-23981	50	43	are	be	AUX
bjp-23981	50	44	not	not	PART
bjp-23981	50	45	drugs	drug	NOUN
bjp-23981	50	46	(	(	PUNCT
bjp-23981	50	47	ertl	ertl	PROPN
bjp-23981	50	48	et	et	PROPN
bjp-23981	50	49	al	al	PROPN
bjp-23981	50	50	.	.	PROPN
bjp-23981	50	51	,	,	PUNCT
bjp-23981	50	52	2000	2000	NUM
bjp-23981	50	53	)	)	PUNCT
bjp-23981	50	54	.	.	PUNCT
bjp-23981	51	1	the	the	DET
bjp-23981	51	2	%	%	NOUN
bjp-23981	51	3	abs	ab	NOUN
bjp-23981	51	4	was	be	AUX
bjp-23981	51	5	estimated	estimate	VERB
bjp-23981	51	6	according	accord	VERB
bjp-23981	51	7	to	to	ADP
bjp-23981	51	8	the	the	DET
bjp-23981	51	9	formula	formula	NOUN
bjp-23981	51	10	:	:	PUNCT
bjp-23981	52	1	%	%	INTJ
bjp-23981	52	2	abs	ab	NOUN
bjp-23981	52	3	=	=	SYM
bjp-23981	52	4	109—(0.345	109—(0.345	NUM
bjp-23981	52	5	x	x	SYM
bjp-23981	52	6	tpsa	tpsa	NOUN
bjp-23981	52	7	)	)	PUNCT
bjp-23981	52	8	molecular	molecular	ADJ
bjp-23981	52	9	docking	docking	NOUN
bjp-23981	52	10	studies	study	NOUN
bjp-23981	52	11	crystallographic	crystallographic	ADJ
bjp-23981	52	12	data	datum	NOUN
bjp-23981	52	13	of	of	ADP
bjp-23981	52	14	the	the	DET
bjp-23981	52	15	factor	factor	NOUN
bjp-23981	52	16	xa	xa	PROPN
bjp-23981	52	17	enzyme	enzyme	PROPN
bjp-23981	52	18	(	(	PUNCT
bjp-23981	52	19	pdb	pdb	NOUN
bjp-23981	52	20	-	-	PUNCT
bjp-23981	52	21	id	id	ADJ
bjp-23981	52	22	:	:	PUNCT
bjp-23981	52	23	1nfy	1nfy	NOUN
bjp-23981	52	24	)	)	PUNCT
bjp-23981	52	25	was	be	AUX
bjp-23981	52	26	used	use	VERB
bjp-23981	52	27	for	for	ADP
bjp-23981	52	28	docking	dock	VERB
bjp-23981	52	29	studies	study	NOUN
bjp-23981	52	30	.	.	PUNCT
bjp-23981	53	1	the	the	DET
bjp-23981	53	2	x	x	NOUN
bjp-23981	53	3	-	-	NOUN
bjp-23981	53	4	ray	ray	NOUN
bjp-23981	53	5	crystal	crystal	NOUN
bjp-23981	53	6	structure	structure	NOUN
bjp-23981	53	7	of	of	ADP
bjp-23981	53	8	1nfy	1nfy	NUM
bjp-23981	53	9	was	be	AUX
bjp-23981	53	10	downloaded	download	VERB
bjp-23981	53	11	from	from	ADP
bjp-23981	53	12	(	(	PUNCT
bjp-23981	53	13	http://	http://	PROPN
bjp-23981	53	14	www.pdb.org	www.pdb.org	PROPN
bjp-23981	53	15	)	)	PUNCT
bjp-23981	53	16	.	.	PUNCT
bjp-23981	54	1	the	the	DET
bjp-23981	54	2	compounds	compound	NOUN
bjp-23981	54	3	were	be	AUX
bjp-23981	54	4	docked	dock	VERB
bjp-23981	54	5	into	into	ADP
bjp-23981	54	6	1nfy	1nfy	NUM
bjp-23981	54	7	to	to	PART
bjp-23981	54	8	understand	understand	VERB
bjp-23981	54	9	antithrombotic	antithrombotic	ADJ
bjp-23981	54	10	efficacy	efficacy	NOUN
bjp-23981	54	11	of	of	ADP
bjp-23981	54	12	the	the	DET
bjp-23981	54	13	designed	design	VERB
bjp-23981	54	14	1,3,4	1,3,4	NUM
bjp-23981	54	15	-	-	NOUN
bjp-23981	54	16	oxadiazoles	oxadiazole	NOUN
bjp-23981	54	17	.	.	PUNCT
bjp-23981	55	1	in	in	ADP
bjp-23981	55	2	view	view	NOUN
bjp-23981	55	3	of	of	ADP
bjp-23981	55	4	the	the	DET
bjp-23981	55	5	fact	fact	NOUN
bjp-23981	55	6	that	that	SCONJ
bjp-23981	55	7	1nfy	1nfy	NOUN
bjp-23981	55	8	has	have	AUX
bjp-23981	55	9	been	be	AUX
bjp-23981	55	10	well	well	ADV
bjp-23981	55	11	established	establish	VERB
bjp-23981	55	12	and	and	CCONJ
bjp-23981	55	13	reported	report	VERB
bjp-23981	55	14	for	for	ADP
bjp-23981	55	15	docking	dock	VERB
bjp-23981	55	16	analysis	analysis	NOUN
bjp-23981	55	17	to	to	PART
bjp-23981	55	18	understand	understand	VERB
bjp-23981	55	19	antithrombotic	antithrombotic	ADJ
bjp-23981	55	20	importance	importance	NOUN
bjp-23981	55	21	(	(	PUNCT
bjp-23981	55	22	amin	amin	NOUN
bjp-23981	55	23	et	et	PROPN
bjp-23981	55	24	al	al	PROPN
bjp-23981	55	25	.	.	PROPN
bjp-23981	55	26	,	,	PUNCT
bjp-23981	55	27	2014	2014	NUM
bjp-23981	55	28	)	)	PUNCT
bjp-23981	55	29	.	.	PUNCT
bjp-23981	56	1	the	the	DET
bjp-23981	56	2	protein	protein	NOUN
bjp-23981	56	3	structure	structure	NOUN
bjp-23981	56	4	of	of	ADP
bjp-23981	56	5	1nfy	1nfy	NUM
bjp-23981	56	6	is	be	AUX
bjp-23981	56	7	well	well	ADV
bjp-23981	56	8	established	establish	VERB
bjp-23981	56	9	with	with	ADP
bjp-23981	56	10	hydrophobic	hydrophobic	NOUN
bjp-23981	56	11	active	active	ADJ
bjp-23981	56	12	site	site	NOUN
bjp-23981	56	13	and	and	CCONJ
bjp-23981	56	14	the	the	DET
bjp-23981	56	15	proteins	protein	NOUN
bjp-23981	56	16	were	be	AUX
bjp-23981	56	17	determined	determine	VERB
bjp-23981	56	18	at	at	ADP
bjp-23981	56	19	2.1	2.1	NUM
bjp-23981	56	20	å	å	NOUN
bjp-23981	56	21	resolution	resolution	NOUN
bjp-23981	56	22	.	.	PUNCT
bjp-23981	57	1	the	the	DET
bjp-23981	57	2	bound	bind	VERB
bjp-23981	57	3	conformations	conformation	NOUN
bjp-23981	57	4	of	of	ADP
bjp-23981	57	5	4	4	NUM
bjp-23981	57	6	-	-	PUNCT
bjp-23981	57	7	(	(	PUNCT
bjp-23981	57	8	{	{	PUNCT
bjp-23981	57	9	4-[(6	4-[(6	NOUN
bjp-23981	57	10	-	-	PUNCT
bjp-23981	57	11	chloro-1	chloro-1	NUM
bjp-23981	57	12	-	-	PUNCT
bjp-23981	57	13	benzothien	benzothien	NOUN
bjp-23981	57	14	-2	-2	NOUN
bjp-23981	57	15	-	-	PUNCT
bjp-23981	57	16	yl	yl	NOUN
bjp-23981	57	17	)	)	PUNCT
bjp-23981	57	18	sulfonyl]-2oxopiperazine-1	sulfonyl]-2oxopiperazine-1	NOUN
bjp-23981	57	19	-	-	PUNCT
bjp-23981	57	20	yl}methyl)benzene	yl}methyl)benzene	ADJ
bjp-23981	57	21	carboximidamide	carboximidamide	NOUN
bjp-23981	57	22	(	(	PUNCT
bjp-23981	57	23	rpr132747	rpr132747	PROPN
bjp-23981	57	24	)	)	PUNCT
bjp-23981	57	25	was	be	AUX
bjp-23981	57	26	used	use	VERB
bjp-23981	57	27	as	as	ADP
bjp-23981	57	28	controls	control	NOUN
bjp-23981	57	29	in	in	ADP
bjp-23981	57	30	order	order	NOUN
bjp-23981	57	31	to	to	PART
bjp-23981	57	32	define	define	VERB
bjp-23981	57	33	the	the	DET
bjp-23981	57	34	active	active	ADJ
bjp-23981	57	35	site	site	NOUN
bjp-23981	57	36	in	in	ADP
bjp-23981	57	37	factor	factor	NOUN
bjp-23981	57	38	xa	xa	PROPN
bjp-23981	57	39	(	(	PUNCT
bjp-23981	57	40	figure	figure	NOUN
bjp-23981	57	41	2	2	NUM
bjp-23981	57	42	)	)	PUNCT
bjp-23981	57	43	.	.	PUNCT
bjp-23981	58	1	the	the	DET
bjp-23981	58	2	protein	protein	NOUN
bjp-23981	58	3	was	be	AUX
bjp-23981	58	4	prepared	prepare	VERB
bjp-23981	58	5	using	use	VERB
bjp-23981	58	6	a	a	DET
bjp-23981	58	7	protein	protein	NOUN
bjp-23981	58	8	preparation	preparation	NOUN
bjp-23981	58	9	module	module	NOUN
bjp-23981	58	10	in	in	ADP
bjp-23981	58	11	sybylx	sybylx	NOUN
bjp-23981	58	12	2.1	2.1	NUM
bjp-23981	58	13	,	,	PUNCT
bjp-23981	58	14	where	where	SCONJ
bjp-23981	58	15	bond	bond	NOUN
bjp-23981	58	16	orders	order	NOUN
bjp-23981	58	17	were	be	AUX
bjp-23981	58	18	assigned	assign	VERB
bjp-23981	58	19	,	,	PUNCT
bjp-23981	58	20	water	water	NOUN
bjp-23981	58	21	and	and	CCONJ
bjp-23981	58	22	other	other	ADJ
bjp-23981	58	23	residues	residue	NOUN
bjp-23981	58	24	were	be	AUX
bjp-23981	58	25	removed	remove	VERB
bjp-23981	58	26	and	and	CCONJ
bjp-23981	58	27	the	the	DET
bjp-23981	58	28	protein	protein	NOUN
bjp-23981	58	29	model	model	NOUN
bjp-23981	58	30	was	be	AUX
bjp-23981	58	31	charged	charge	VERB
bjp-23981	58	32	with	with	ADP
bjp-23981	58	33	amber7	amber7	ADJ
bjp-23981	58	34	ff99	ff99	PROPN
bjp-23981	58	35	.	.	PUNCT
bjp-23981	59	1	ligands	ligand	NOUN
bjp-23981	59	2	,	,	PUNCT
bjp-23981	59	3	1,3,4	1,3,4	NUM
bjp-23981	59	4	-	-	NOUN
bjp-23981	59	5	oxadiazoles	oxadiazole	NOUN
bjp-23981	59	6	4a-4k	4a-4k	NUM
bjp-23981	59	7	were	be	AUX
bjp-23981	59	8	drawn	draw	VERB
bjp-23981	59	9	in	in	ADP
bjp-23981	59	10	chem	chem	NOUN
bjp-23981	59	11	draw	draw	NOUN
bjp-23981	59	12	and	and	CCONJ
bjp-23981	59	13	molecules	molecule	NOUN
bjp-23981	59	14	were	be	AUX
bjp-23981	59	15	converted	convert	VERB
bjp-23981	59	16	into	into	ADP
bjp-23981	59	17	*	*	ADJ
bjp-23981	59	18	.sdf	.sdf	NOUN
bjp-23981	59	19	using	use	VERB
bjp-23981	59	20	open	open	ADJ
bjp-23981	59	21	babel	babel	NOUN
bjp-23981	59	22	software	software	NOUN
bjp-23981	59	23	.	.	PUNCT
bjp-23981	60	1	using	use	VERB
bjp-23981	60	2	the	the	DET
bjp-23981	60	3	ligand	ligand	ADJ
bjp-23981	60	4	preparation	preparation	NOUN
bjp-23981	60	5	utility	utility	NOUN
bjp-23981	60	6	of	of	ADP
bjp-23981	60	7	sybylx	sybylx	NOUN
bjp-23981	60	8	2.1	2.1	NUM
bjp-23981	60	9	,	,	PUNCT
bjp-23981	60	10	3d	3d	NUM
bjp-23981	60	11	structures	structure	NOUN
bjp-23981	60	12	were	be	AUX
bjp-23981	60	13	generated	generate	VERB
bjp-23981	60	14	from	from	ADP
bjp-23981	60	15	2d	2d	NUM
bjp-23981	60	16	and	and	CCONJ
bjp-23981	60	17	the	the	DET
bjp-23981	60	18	ligands	ligand	NOUN
bjp-23981	60	19	were	be	AUX
bjp-23981	60	20	energy	energy	NOUN
bjp-23981	60	21	minimized	minimized	NOUN
bjp-23981	60	22	using	use	VERB
bjp-23981	60	23	minimize	minimize	NOUN
bjp-23981	60	24	module	module	NOUN
bjp-23981	60	25	of	of	ADP
bjp-23981	60	26	sybyl	sybyl	NOUN
bjp-23981	60	27	x	x	PUNCT
bjp-23981	60	28	2.1	2.1	NUM
bjp-23981	60	29	by	by	ADP
bjp-23981	60	30	applying	apply	VERB
bjp-23981	60	31	molecular	molecular	ADJ
bjp-23981	60	32	mechanics	mechanic	NOUN
bjp-23981	60	33	force	force	NOUN
bjp-23981	60	34	fields	field	NOUN
bjp-23981	60	35	(	(	PUNCT
bjp-23981	60	36	mmff94s	mmff94s	PROPN
bjp-23981	60	37	)	)	PUNCT
bjp-23981	60	38	and	and	CCONJ
bjp-23981	60	39	charged	charge	VERB
bjp-23981	60	40	using	use	VERB
bjp-23981	60	41	gasteiger	gasteiger	NOUN
bjp-23981	60	42	-	-	PUNCT
bjp-23981	60	43	marsili	marsili	NOUN
bjp-23981	60	44	method	method	NOUN
bjp-23981	60	45	.	.	PUNCT
bjp-23981	61	1	molecular	molecular	ADJ
bjp-23981	61	2	docking	docking	NOUN
bjp-23981	61	3	simulations	simulation	NOUN
bjp-23981	61	4	were	be	AUX
bjp-23981	61	5	performed	perform	VERB
bjp-23981	61	6	in	in	ADP
bjp-23981	61	7	order	order	NOUN
bjp-23981	61	8	to	to	PART
bjp-23981	61	9	distinguish	distinguish	VERB
bjp-23981	61	10	the	the	DET
bjp-23981	61	11	basic	basic	ADJ
bjp-23981	61	12	receptor	receptor	NOUN
bjp-23981	61	13	-	-	PUNCT
bjp-23981	61	14	ligand	ligand	NOUN
bjp-23981	61	15	interactions	interaction	NOUN
bjp-23981	61	16	.	.	PUNCT
bjp-23981	62	1	the	the	DET
bjp-23981	62	2	docking	dock	VERB
bjp-23981	62	3	experiments	experiment	NOUN
bjp-23981	62	4	were	be	AUX
bjp-23981	62	5	carried	carry	VERB
bjp-23981	62	6	using	use	VERB
bjp-23981	62	7	the	the	DET
bjp-23981	62	8	sybyl	sybyl	NOUN
bjp-23981	62	9	x	x	PUNCT
bjp-23981	62	10	2.1	2.1	NUM
bjp-23981	62	11	.	.	PUNCT
bjp-23981	63	1	the	the	DET
bjp-23981	63	2	optimized	optimize	VERB
bjp-23981	63	3	3d	3d	NUM
bjp-23981	63	4	-	-	PUNCT
bjp-23981	63	5	structures	structure	NOUN
bjp-23981	63	6	of	of	ADP
bjp-23981	63	7	1,3,4	1,3,4	NUM
bjp-23981	63	8	-	-	PUNCT
bjp-23981	63	9	oxadiazoles	oxadiazole	NOUN
bjp-23981	63	10	4a-4k	4a-4k	NUM
bjp-23981	63	11	were	be	AUX
bjp-23981	63	12	docked	dock	VERB
bjp-23981	63	13	within	within	ADP
bjp-23981	63	14	10	10	NUM
bjp-23981	63	15	å	å	PROPN
bjp-23981	63	16	radius	radius	NOUN
bjp-23981	63	17	to	to	PART
bjp-23981	63	18	find	find	VERB
bjp-23981	63	19	the	the	DET
bjp-23981	63	20	most	most	ADV
bjp-23981	63	21	optimal	optimal	ADJ
bjp-23981	63	22	binding	binding	ADJ
bjp-23981	63	23	pose	pose	NOUN
bjp-23981	63	24	of	of	ADP
bjp-23981	63	25	each	each	DET
bjp-23981	63	26	ligand	ligand	NOUN
bjp-23981	63	27	.	.	PUNCT
bjp-23981	64	1	the	the	DET
bjp-23981	64	2	docking	docking	NOUN
bjp-23981	64	3	algorithm	algorithm	NOUN
bjp-23981	64	4	performs	perform	VERB
bjp-23981	64	5	a	a	DET
bjp-23981	64	6	series	series	NOUN
bjp-23981	64	7	of	of	ADP
bjp-23981	64	8	hierarchical	hierarchical	ADJ
bjp-23981	64	9	searches	search	NOUN
bjp-23981	64	10	for	for	ADP
bjp-23981	64	11	locations	location	NOUN
bjp-23981	64	12	of	of	ADP
bjp-23981	64	13	possible	possible	ADJ
bjp-23981	64	14	ligand	ligand	ADJ
bjp-23981	64	15	affinity	affinity	NOUN
bjp-23981	64	16	within	within	ADP
bjp-23981	64	17	the	the	DET
bjp-23981	64	18	binding	bind	VERB
bjp-23981	64	19	site	site	NOUN
bjp-23981	64	20	of	of	ADP
bjp-23981	64	21	the	the	DET
bjp-23981	64	22	enzyme	enzyme	NOUN
bjp-23981	64	23	.	.	PUNCT
bjp-23981	65	1	the	the	DET
bjp-23981	65	2	score	score	NOUN
bjp-23981	65	3	of	of	ADP
bjp-23981	65	4	the	the	DET
bjp-23981	65	5	docked	dock	VERB
bjp-23981	65	6	molecules	molecule	NOUN
bjp-23981	65	7	were	be	AUX
bjp-23981	65	8	obtained	obtain	VERB
bjp-23981	65	9	,	,	PUNCT
bjp-23981	65	10	which	which	PRON
bjp-23981	65	11	indicate	indicate	VERB
bjp-23981	65	12	the	the	DET
bjp-23981	65	13	affinity	affinity	NOUN
bjp-23981	65	14	of	of	ADP
bjp-23981	65	15	the	the	DET
bjp-23981	65	16	molecules	molecule	NOUN
bjp-23981	65	17	towards	towards	ADP
bjp-23981	65	18	the	the	DET
bjp-23981	65	19	enzyme	enzyme	NOUN
bjp-23981	65	20	core	core	NOUN
bjp-23981	65	21	.	.	PUNCT
bjp-23981	66	1	chemicals	chemical	NOUN
bjp-23981	66	2	the	the	DET
bjp-23981	66	3	chemicals	chemical	NOUN
bjp-23981	66	4	were	be	AUX
bjp-23981	66	5	procured	procure	VERB
bjp-23981	66	6	from	from	ADP
bjp-23981	66	7	sigma	sigma	PROPN
bjp-23981	66	8	-	-	PUNCT
bjp-23981	66	9	aldrich	aldrich	PROPN
bjp-23981	66	10	and	and	CCONJ
bjp-23981	66	11	were	be	AUX
bjp-23981	66	12	used	use	VERB
bjp-23981	66	13	without	without	ADP
bjp-23981	66	14	further	further	ADJ
bjp-23981	66	15	purification	purification	NOUN
bjp-23981	66	16	.	.	PUNCT
bjp-23981	67	1	in	in	ADP
bjp-23981	67	2	vitro	vitro	X
bjp-23981	67	3	thrombolytic	thrombolytic	ADJ
bjp-23981	67	4	evaluation	evaluation	NOUN
bjp-23981	67	5	in	in	ADP
bjp-23981	67	6	vitro	vitro	X
bjp-23981	67	7	test	test	NOUN
bjp-23981	67	8	adapted	adapt	VERB
bjp-23981	67	9	for	for	ADP
bjp-23981	67	10	screening	screening	NOUN
bjp-23981	67	11	of	of	ADP
bjp-23981	67	12	test	test	NOUN
bjp-23981	67	13	compounds	compound	NOUN
bjp-23981	67	14	for	for	ADP
bjp-23981	67	15	clot	clot	NOUN
bjp-23981	67	16	lysis	lysis	NOUN
bjp-23981	67	17	study	study	NOUN
bjp-23981	67	18	was	be	AUX
bjp-23981	67	19	performed	perform	VERB
bjp-23981	67	20	on	on	ADP
bjp-23981	67	21	whole	whole	ADJ
bjp-23981	67	22	blood	blood	NOUN
bjp-23981	67	23	as	as	ADP
bjp-23981	67	24	per	per	ADP
bjp-23981	67	25	the	the	DET
bjp-23981	67	26	reported	report	VERB
bjp-23981	67	27	method	method	NOUN
bjp-23981	67	28	(	(	PUNCT
bjp-23981	67	29	prasad	prasad	PROPN
bjp-23981	67	30	et	et	PROPN
bjp-23981	67	31	al	al	PROPN
bjp-23981	67	32	.	.	PROPN
bjp-23981	67	33	,	,	PUNCT
bjp-23981	67	34	2006	2006	NUM
bjp-23981	67	35	)	)	PUNCT
bjp-23981	67	36	.	.	PUNCT
bjp-23981	68	1	the	the	DET
bjp-23981	68	2	blood	blood	NOUN
bjp-23981	68	3	samples	sample	NOUN
bjp-23981	68	4	were	be	AUX
bjp-23981	68	5	collected	collect	VERB
bjp-23981	68	6	from	from	ADP
bjp-23981	68	7	butcher	butcher	PROPN
bjp-23981	68	8	house	house	PROPN
bjp-23981	68	9	of	of	ADP
bjp-23981	68	10	healthy	healthy	ADJ
bjp-23981	68	11	sheep	sheep	NOUN
bjp-23981	68	12	(	(	PUNCT
bjp-23981	68	13	ovis	ovis	ADJ
bjp-23981	68	14	aries	arie	NOUN
bjp-23981	68	15	)	)	PUNCT
bjp-23981	68	16	.	.	PUNCT
bjp-23981	69	1	the	the	DET
bjp-23981	69	2	entire	entire	ADJ
bjp-23981	69	3	procedure	procedure	NOUN
bjp-23981	69	4	was	be	AUX
bjp-23981	69	5	carried	carry	VERB
bjp-23981	69	6	out	out	ADP
bjp-23981	69	7	at	at	ADP
bjp-23981	69	8	room	room	NOUN
bjp-23981	69	9	temperature	temperature	NOUN
bjp-23981	69	10	and	and	CCONJ
bjp-23981	69	11	studies	study	NOUN
bjp-23981	69	12	were	be	AUX
bjp-23981	69	13	required	require	VERB
bjp-23981	69	14	to	to	PART
bjp-23981	69	15	be	be	AUX
bjp-23981	69	16	completed	complete	VERB
bjp-23981	69	17	within	within	ADP
bjp-23981	69	18	3	3	NUM
bjp-23981	69	19	hours	hour	NOUN
bjp-23981	69	20	after	after	ADP
bjp-23981	69	21	blood	blood	NOUN
bjp-23981	69	22	withdrawal	withdrawal	NOUN
bjp-23981	69	23	as	as	ADP
bjp-23981	69	24	per	per	ADP
bjp-23981	69	25	the	the	DET
bjp-23981	69	26	protocol	protocol	NOUN
bjp-23981	69	27	.	.	PUNCT
bjp-23981	70	1	phosphate	phosphate	ADJ
bjp-23981	70	2	buffered	buffer	VERB
bjp-23981	70	3	saline	saline	NOUN
bjp-23981	70	4	(	(	PUNCT
bjp-23981	70	5	pbs	pbs	PROPN
bjp-23981	70	6	)	)	PUNCT
bjp-23981	70	7	was	be	AUX
bjp-23981	70	8	used	use	VERB
bjp-23981	70	9	as	as	ADP
bjp-23981	70	10	control	control	NOUN
bjp-23981	70	11	and	and	CCONJ
bjp-23981	70	12	test	test	NOUN
bjp-23981	70	13	compounds	compound	NOUN
bjp-23981	70	14	were	be	AUX
bjp-23981	70	15	screened	screen	VERB
bjp-23981	70	16	at	at	ADP
bjp-23981	70	17	6.25	6.25	NUM
bjp-23981	70	18	,	,	PUNCT
bjp-23981	71	1	r	r	NOUN
bjp-23981	71	2	cys191agly216a	cys191agly216a	NOUN
bjp-23981	71	3	ala190a	ala190a	NUM
bjp-23981	71	4	phe174a	phe174a	PROPN
bjp-23981	71	5	trp215a	trp215a	PRON
bjp-23981	71	6	h2n	h2n	PROPN
bjp-23981	71	7	gly218a	gly218a	PROPN
bjp-23981	72	1	nh2	nh2	PROPN
bjp-23981	72	2	r	r	NOUN
bjp-23981	72	3	o	o	PROPN
bjp-23981	72	4	h	h	NOUN
bjp-23981	72	5	n	n	ADP
bjp-23981	72	6	o	o	NOUN
bjp-23981	72	7	n	n	CCONJ
bjp-23981	72	8	n	n	PROPN
bjp-23981	72	9	s	s	PART
bjp-23981	72	10	o	o	NOUN
bjp-23981	72	11	o	o	X
bjp-23981	72	12	s	s	X
bjp-23981	72	13	ci	ci	NOUN
bjp-23981	72	14	figure	figure	NOUN
bjp-23981	72	15	2	2	NUM
bjp-23981	72	16	:	:	PUNCT
bjp-23981	72	17	graphical	graphical	ADJ
bjp-23981	72	18	representation	representation	NOUN
bjp-23981	72	19	of	of	ADP
bjp-23981	72	20	rpr132747	rpr132747	NOUN
bjp-23981	72	21	interaction	interaction	NOUN
bjp-23981	72	22	with	with	ADP
bjp-23981	72	23	protein	protein	NOUN
bjp-23981	72	24	1nfy	1nfy	PROPN
bjp-23981	72	25	bangladesh	bangladesh	NOUN
bjp-23981	72	26	j	j	PROPN
bjp-23981	72	27	pharmacol	pharmacol	PROPN
bjp-23981	72	28	2016	2016	NUM
bjp-23981	72	29	;	;	PUNCT
bjp-23981	72	30	11	11	NUM
bjp-23981	72	31	:	:	SYM
bjp-23981	72	32	67	67	NUM
bjp-23981	72	33	-	-	SYM
bjp-23981	72	34	74	74	NUM
bjp-23981	72	35	69	69	NUM
bjp-23981	72	36	http://www.molinspiration.com	http://www.molinspiration.com	X
bjp-23981	72	37	http://www.pdb.org	http://www.pdb.org	NOUN
bjp-23981	72	38	http://www.pdb.org	http://www.pdb.org	NOUN
bjp-23981	72	39	12.5	12.5	NUM
bjp-23981	72	40	and	and	CCONJ
bjp-23981	72	41	25	25	NUM
bjp-23981	72	42	µm	µm	NOUN
bjp-23981	72	43	concentrations	concentration	NOUN
bjp-23981	72	44	,	,	PUNCT
bjp-23981	72	45	respectively	respectively	ADV
bjp-23981	72	46	.	.	PUNCT
bjp-23981	73	1	the	the	DET
bjp-23981	73	2	commercially	commercially	ADV
bjp-23981	73	3	available	available	ADJ
bjp-23981	73	4	lyophilized	lyophilize	VERB
bjp-23981	73	5	streptokinase	streptokinase	PROPN
bjp-23981	73	6	vial	vial	NOUN
bjp-23981	73	7	(	(	PUNCT
bjp-23981	73	8	1,500,000	1,500,000	NUM
bjp-23981	73	9	iu	iu	NOUN
bjp-23981	73	10	)	)	PUNCT
bjp-23981	73	11	was	be	AUX
bjp-23981	73	12	diluted	dilute	VERB
bjp-23981	73	13	with	with	ADP
bjp-23981	73	14	pbs	pbs	PROPN
bjp-23981	73	15	and	and	CCONJ
bjp-23981	73	16	mixed	mix	VERB
bjp-23981	73	17	properly	properly	ADV
bjp-23981	73	18	.	.	PUNCT
bjp-23981	74	1	from	from	ADP
bjp-23981	74	2	which	which	PRON
bjp-23981	74	3	streptokinase	streptokinase	PROPN
bjp-23981	74	4	equivalent	equivalent	ADJ
bjp-23981	74	5	to	to	ADP
bjp-23981	74	6	30,000	30,000	NUM
bjp-23981	74	7	iu	iu	ADP
bjp-23981	74	8	was	be	AUX
bjp-23981	74	9	used	use	VERB
bjp-23981	74	10	as	as	ADP
bjp-23981	74	11	a	a	DET
bjp-23981	74	12	standard	standard	NOUN
bjp-23981	74	13	to	to	PART
bjp-23981	74	14	observe	observe	VERB
bjp-23981	74	15	the	the	DET
bjp-23981	74	16	thrombolytic	thrombolytic	ADJ
bjp-23981	74	17	activity	activity	NOUN
bjp-23981	74	18	.	.	PUNCT
bjp-23981	75	1	whole	whole	ADJ
bjp-23981	75	2	blood	blood	NOUN
bjp-23981	75	3	was	be	AUX
bjp-23981	75	4	collected	collect	VERB
bjp-23981	75	5	and	and	CCONJ
bjp-23981	75	6	500	500	NUM
bjp-23981	75	7	μl	μl	NOUN
bjp-23981	75	8	of	of	ADP
bjp-23981	75	9	blood	blood	NOUN
bjp-23981	75	10	was	be	AUX
bjp-23981	75	11	transferred	transfer	VERB
bjp-23981	75	12	to	to	ADP
bjp-23981	75	13	each	each	PRON
bjp-23981	75	14	of	of	ADP
bjp-23981	75	15	the	the	DET
bjp-23981	75	16	previously	previously	ADV
bjp-23981	75	17	weighed	weigh	VERB
bjp-23981	75	18	micro	micro	ADJ
bjp-23981	75	19	centrifuge	centrifuge	NOUN
bjp-23981	75	20	tubes	tube	NOUN
bjp-23981	75	21	and	and	CCONJ
bjp-23981	75	22	incubated	incubate	VERB
bjp-23981	75	23	at	at	ADP
bjp-23981	75	24	37	37	NUM
bjp-23981	75	25	°	°	ADP
bjp-23981	75	26	c	c	NOUN
bjp-23981	75	27	for	for	ADP
bjp-23981	75	28	45	45	NUM
bjp-23981	75	29	min	min	NOUN
bjp-23981	75	30	for	for	ADP
bjp-23981	75	31	clot	clot	NOUN
bjp-23981	75	32	formation	formation	NOUN
bjp-23981	75	33	.	.	PUNCT
bjp-23981	76	1	after	after	ADP
bjp-23981	76	2	clot	clot	NOUN
bjp-23981	76	3	formation	formation	NOUN
bjp-23981	76	4	,	,	PUNCT
bjp-23981	76	5	serum	serum	NOUN
bjp-23981	76	6	was	be	AUX
bjp-23981	76	7	completely	completely	ADV
bjp-23981	76	8	removed	remove	VERB
bjp-23981	76	9	(	(	PUNCT
bjp-23981	76	10	aspirated	aspirate	VERB
bjp-23981	76	11	out	out	ADP
bjp-23981	76	12	without	without	ADP
bjp-23981	76	13	disturbing	disturb	VERB
bjp-23981	76	14	the	the	DET
bjp-23981	76	15	clot	clot	NOUN
bjp-23981	76	16	formed	form	VERB
bjp-23981	76	17	)	)	PUNCT
bjp-23981	76	18	and	and	CCONJ
bjp-23981	76	19	each	each	DET
bjp-23981	76	20	tube	tube	NOUN
bjp-23981	76	21	with	with	ADP
bjp-23981	76	22	the	the	DET
bjp-23981	76	23	clot	clot	NOUN
bjp-23981	76	24	was	be	AUX
bjp-23981	76	25	again	again	ADV
bjp-23981	76	26	weighed	weigh	VERB
bjp-23981	76	27	to	to	PART
bjp-23981	76	28	determine	determine	VERB
bjp-23981	76	29	the	the	DET
bjp-23981	76	30	clot	clot	NOUN
bjp-23981	76	31	weight	weight	NOUN
bjp-23981	76	32	.	.	PUNCT
bjp-23981	77	1	100	100	NUM
bjp-23981	77	2	μl	μl	ADP
bjp-23981	77	3	of	of	ADP
bjp-23981	77	4	diluted	diluted	ADJ
bjp-23981	77	5	test	test	NOUN
bjp-23981	77	6	compounds	compound	NOUN
bjp-23981	77	7	(	(	PUNCT
bjp-23981	77	8	6.25	6.25	NUM
bjp-23981	77	9	,	,	PUNCT
bjp-23981	77	10	12.5	12.5	NUM
bjp-23981	77	11	and	and	CCONJ
bjp-23981	77	12	25	25	NUM
bjp-23981	77	13	µm	µm	NOUN
bjp-23981	77	14	)	)	PUNCT
bjp-23981	77	15	for	for	ADP
bjp-23981	77	16	screening	screen	VERB
bjp-23981	77	17	were	be	AUX
bjp-23981	77	18	added	add	VERB
bjp-23981	77	19	to	to	ADP
bjp-23981	77	20	the	the	DET
bjp-23981	77	21	labeled	label	VERB
bjp-23981	77	22	microcentrifuge	microcentrifuge	PROPN
bjp-23981	77	23	tube	tube	NOUN
bjp-23981	77	24	containing	contain	VERB
bjp-23981	77	25	clot	clot	NOUN
bjp-23981	77	26	.	.	PUNCT
bjp-23981	78	1	100	100	NUM
bjp-23981	78	2	μl	μl	ADP
bjp-23981	78	3	of	of	ADP
bjp-23981	78	4	streptokinase	streptokinase	PROPN
bjp-23981	78	5	(	(	PUNCT
bjp-23981	78	6	30,000	30,000	NUM
bjp-23981	78	7	iu	iu	NOUN
bjp-23981	78	8	)	)	PUNCT
bjp-23981	78	9	was	be	AUX
bjp-23981	78	10	added	add	VERB
bjp-23981	78	11	as	as	ADP
bjp-23981	78	12	the	the	DET
bjp-23981	78	13	positive	positive	ADJ
bjp-23981	78	14	thrombolytic	thrombolytic	ADJ
bjp-23981	78	15	control	control	NOUN
bjp-23981	78	16	and	and	CCONJ
bjp-23981	78	17	100	100	NUM
bjp-23981	78	18	μl	μl	ADP
bjp-23981	78	19	of	of	ADP
bjp-23981	78	20	pbs	pbs	PROPN
bjp-23981	78	21	as	as	SCONJ
bjp-23981	78	22	the	the	DET
bjp-23981	78	23	negative	negative	ADJ
bjp-23981	78	24	thrombolytic	thrombolytic	ADJ
bjp-23981	78	25	control	control	NOUN
bjp-23981	78	26	was	be	AUX
bjp-23981	78	27	employed	employ	VERB
bjp-23981	78	28	.	.	PUNCT
bjp-23981	79	1	all	all	DET
bjp-23981	79	2	the	the	DET
bjp-23981	79	3	tubes	tube	NOUN
bjp-23981	79	4	were	be	AUX
bjp-23981	79	5	then	then	ADV
bjp-23981	79	6	again	again	ADV
bjp-23981	79	7	incubated	incubate	VERB
bjp-23981	79	8	at	at	ADP
bjp-23981	79	9	37	37	NUM
bjp-23981	79	10	°	°	ADP
bjp-23981	79	11	c	c	NOUN
bjp-23981	79	12	for	for	ADP
bjp-23981	79	13	90	90	NUM
bjp-23981	79	14	min	min	NOUN
bjp-23981	79	15	and	and	CCONJ
bjp-23981	79	16	observed	observe	VERB
bjp-23981	79	17	for	for	ADP
bjp-23981	79	18	clot	clot	NOUN
bjp-23981	79	19	lysis	lysis	NOUN
bjp-23981	79	20	.	.	PUNCT
bjp-23981	80	1	after	after	ADP
bjp-23981	80	2	incubation	incubation	NOUN
bjp-23981	80	3	,	,	PUNCT
bjp-23981	80	4	fluid	fluid	NOUN
bjp-23981	80	5	obtained	obtain	VERB
bjp-23981	80	6	was	be	AUX
bjp-23981	80	7	removed	remove	VERB
bjp-23981	80	8	and	and	CCONJ
bjp-23981	80	9	tubes	tube	NOUN
bjp-23981	80	10	were	be	AUX
bjp-23981	80	11	again	again	ADV
bjp-23981	80	12	weighed	weigh	VERB
bjp-23981	80	13	to	to	PART
bjp-23981	80	14	observe	observe	VERB
bjp-23981	80	15	the	the	DET
bjp-23981	80	16	difference	difference	NOUN
bjp-23981	80	17	in	in	ADP
bjp-23981	80	18	weight	weight	NOUN
bjp-23981	80	19	after	after	ADP
bjp-23981	80	20	clot	clot	NOUN
bjp-23981	80	21	disruption	disruption	NOUN
bjp-23981	80	22	.	.	PUNCT
bjp-23981	81	1	difference	difference	NOUN
bjp-23981	81	2	obtained	obtain	VERB
bjp-23981	81	3	in	in	ADP
bjp-23981	81	4	weight	weight	NOUN
bjp-23981	81	5	taken	take	VERB
bjp-23981	81	6	before	before	ADV
bjp-23981	81	7	and	and	CCONJ
bjp-23981	81	8	after	after	SCONJ
bjp-23981	81	9	clot	clot	NOUN
bjp-23981	81	10	lysis	lysis	NOUN
bjp-23981	81	11	was	be	AUX
bjp-23981	81	12	expressed	express	VERB
bjp-23981	81	13	as	as	ADP
bjp-23981	81	14	percentage	percentage	NOUN
bjp-23981	81	15	of	of	ADP
bjp-23981	81	16	clot	clot	NOUN
bjp-23981	81	17	lysis	lysis	NOUN
bjp-23981	81	18	.	.	PUNCT
bjp-23981	82	1	the	the	DET
bjp-23981	82	2	percent	percent	NOUN
bjp-23981	82	3	clot	clot	NOUN
bjp-23981	82	4	lysis	lysis	NOUN
bjp-23981	82	5	was	be	AUX
bjp-23981	82	6	calculated	calculate	VERB
bjp-23981	82	7	according	accord	VERB
bjp-23981	82	8	to	to	ADP
bjp-23981	82	9	the	the	DET
bjp-23981	82	10	following	follow	VERB
bjp-23981	82	11	formula	formula	NOUN
bjp-23981	82	12	:	:	PUNCT
bjp-23981	82	13	statistical	statistical	ADJ
bjp-23981	82	14	analysis	analysis	NOUN
bjp-23981	82	15	the	the	DET
bjp-23981	82	16	mean	mean	ADJ
bjp-23981	82	17	clot	clot	NOUN
bjp-23981	82	18	lysis	lysis	NOUN
bjp-23981	82	19	percentage	percentage	NOUN
bjp-23981	82	20	of	of	ADP
bjp-23981	82	21	test	test	NOUN
bjp-23981	82	22	compounds	compound	NOUN
bjp-23981	82	23	in	in	ADP
bjp-23981	82	24	different	different	ADJ
bjp-23981	82	25	concentrations	concentration	NOUN
bjp-23981	82	26	was	be	AUX
bjp-23981	82	27	compared	compare	VERB
bjp-23981	82	28	with	with	ADP
bjp-23981	82	29	the	the	DET
bjp-23981	82	30	standard	standard	ADJ
bjp-23981	82	31	streptokinase	streptokinase	PROPN
bjp-23981	82	32	and	and	CCONJ
bjp-23981	82	33	phosphate	phosphate	ADJ
bjp-23981	82	34	buffered	buffer	VERB
bjp-23981	82	35	saline	saline	NOUN
bjp-23981	82	36	using	use	VERB
bjp-23981	82	37	the	the	DET
bjp-23981	82	38	repeated	repeat	VERB
bjp-23981	82	39	measures	measure	NOUN
bjp-23981	82	40	anova	anova	X
bjp-23981	82	41	with	with	ADP
bjp-23981	82	42	dunnet	dunnet	NOUN
bjp-23981	82	43	’s	’s	PART
bjp-23981	82	44	test	test	NOUN
bjp-23981	82	45	.	.	PUNCT
bjp-23981	83	1	mean	mean	VERB
bjp-23981	83	2	,	,	PUNCT
bjp-23981	83	3	standard	standard	ADJ
bjp-23981	83	4	error	error	NOUN
bjp-23981	83	5	of	of	ADP
bjp-23981	83	6	mean	mean	PROPN
bjp-23981	83	7	(	(	PUNCT
bjp-23981	83	8	sem	sem	NOUN
bjp-23981	83	9	)	)	PUNCT
bjp-23981	83	10	calculations	calculation	NOUN
bjp-23981	83	11	and	and	CCONJ
bjp-23981	83	12	anova	anova	PROPN
bjp-23981	83	13	test	test	NOUN
bjp-23981	83	14	were	be	AUX
bjp-23981	83	15	performed	perform	VERB
bjp-23981	83	16	using	use	VERB
bjp-23981	83	17	‘	'	PUNCT
bjp-23981	83	18	‘	'	PUNCT
bjp-23981	83	19	graphpad	graphpad	NOUN
bjp-23981	83	20	prism	prism	NOUN
bjp-23981	83	21	version	version	NOUN
bjp-23981	83	22	4.0	4.0	NUM
bjp-23981	83	23	’’	’'	PUNCT
bjp-23981	83	24	software	software	NOUN
bjp-23981	83	25	.	.	PUNCT
bjp-23981	84	1	the	the	DET
bjp-23981	84	2	data	datum	NOUN
bjp-23981	84	3	obtained	obtain	VERB
bjp-23981	84	4	is	be	AUX
bjp-23981	84	5	expressed	express	VERB
bjp-23981	84	6	as	as	ADP
bjp-23981	84	7	mean	mean	PROPN
bjp-23981	84	8	±	±	NUM
bjp-23981	84	9	sem	sem	NOUN
bjp-23981	84	10	.	.	PUNCT
bjp-23981	85	1	the	the	DET
bjp-23981	85	2	concentration	concentration	NOUN
bjp-23981	85	3	which	which	PRON
bjp-23981	85	4	produced	produce	VERB
bjp-23981	85	5	clot	clot	NOUN
bjp-23981	85	6	lysis	lysis	NOUN
bjp-23981	85	7	half	half	NOUN
bjp-23981	85	8	maximally	maximally	ADV
bjp-23981	85	9	(	(	PUNCT
bjp-23981	85	10	ec50	ec50	PROPN
bjp-23981	85	11	)	)	PUNCT
bjp-23981	85	12	was	be	AUX
bjp-23981	85	13	also	also	ADV
bjp-23981	85	14	determined	determine	VERB
bjp-23981	85	15	graphically	graphically	ADV
bjp-23981	85	16	from	from	ADP
bjp-23981	85	17	the	the	DET
bjp-23981	85	18	percentage	percentage	NOUN
bjp-23981	85	19	of	of	ADP
bjp-23981	85	20	clot	clot	NOUN
bjp-23981	85	21	lysis	lysis	NOUN
bjp-23981	85	22	at	at	ADP
bjp-23981	85	23	various	various	ADJ
bjp-23981	85	24	concentrations	concentration	NOUN
bjp-23981	85	25	of	of	ADP
bjp-23981	85	26	the	the	DET
bjp-23981	85	27	test	test	NOUN
bjp-23981	85	28	compound	compound	NOUN
bjp-23981	85	29	.	.	PUNCT
bjp-23981	86	1	results	result	NOUN
bjp-23981	86	2	in	in	ADP
bjp-23981	86	3	silico	silico	NOUN
bjp-23981	86	4	adme	adme	NOUN
bjp-23981	86	5	results	result	VERB
bjp-23981	86	6	molecular	molecular	ADJ
bjp-23981	86	7	weight	weight	NOUN
bjp-23981	86	8	of	of	ADP
bjp-23981	86	9	each	each	DET
bjp-23981	86	10	ligand	ligand	NOUN
bjp-23981	86	11	was	be	AUX
bjp-23981	86	12	within	within	ADP
bjp-23981	86	13	the	the	DET
bjp-23981	86	14	range	range	NOUN
bjp-23981	86	15	of	of	ADP
bjp-23981	86	16	229	229	NUM
bjp-23981	86	17	to	to	ADP
bjp-23981	86	18	395	395	NUM
bjp-23981	86	19	d.	d.	NOUN
bjp-23981	86	20	they	they	PRON
bjp-23981	86	21	also	also	ADV
bjp-23981	86	22	had	have	VERB
bjp-23981	86	23	moderate	moderate	ADJ
bjp-23981	86	24	to	to	PART
bjp-23981	86	25	high	high	ADJ
bjp-23981	86	26	predicted	predict	VERB
bjp-23981	86	27	oral	oral	ADJ
bjp-23981	86	28	availability	availability	NOUN
bjp-23981	86	29	based	base	VERB
bjp-23981	86	30	on	on	ADP
bjp-23981	86	31	%	%	INTJ
bjp-23981	86	32	abs	ab	NOUN
bjp-23981	86	33	ranging	range	VERB
bjp-23981	86	34	between	between	ADP
bjp-23981	86	35	50	50	NUM
bjp-23981	86	36	to	to	PART
bjp-23981	86	37	82	82	NUM
bjp-23981	86	38	%	%	NOUN
bjp-23981	86	39	.	.	PUNCT
bjp-23981	87	1	generally	generally	ADV
bjp-23981	87	2	,	,	PUNCT
bjp-23981	87	3	a	a	DET
bjp-23981	87	4	compound	compound	NOUN
bjp-23981	87	5	needs	need	VERB
bjp-23981	87	6	a	a	DET
bjp-23981	87	7	score	score	NOUN
bjp-23981	87	8	less	less	ADJ
bjp-23981	87	9	than	than	ADP
bjp-23981	87	10	5	5	NUM
bjp-23981	87	11	for	for	ADP
bjp-23981	87	12	lipophilicity	lipophilicity	NOUN
bjp-23981	87	13	,	,	PUNCT
bjp-23981	87	14	the	the	DET
bjp-23981	87	15	lipophilicity	lipophilicity	NOUN
bjp-23981	87	16	data	datum	NOUN
bjp-23981	87	17	suggested	suggest	VERB
bjp-23981	87	18	that	that	SCONJ
bjp-23981	87	19	the	the	DET
bjp-23981	87	20	compounds	compound	NOUN
bjp-23981	87	21	were	be	AUX
bjp-23981	87	22	optimally	optimally	ADV
bjp-23981	87	23	lipophilic	lipophilic	ADJ
bjp-23981	87	24	in	in	ADP
bjp-23981	87	25	nature	nature	NOUN
bjp-23981	87	26	ranging	range	VERB
bjp-23981	87	27	from	from	ADP
bjp-23981	87	28	-0.47	-0.47	PRON
bjp-23981	87	29	to	to	ADP
bjp-23981	87	30	1.92	1.92	NUM
bjp-23981	87	31	.	.	PUNCT
bjp-23981	88	1	all	all	DET
bjp-23981	88	2	the	the	DET
bjp-23981	88	3	compounds	compound	NOUN
bjp-23981	88	4	(	(	PUNCT
bjp-23981	88	5	except	except	SCONJ
bjp-23981	88	6	compound	compound	NOUN
bjp-23981	88	7	4c	4c	NOUN
bjp-23981	88	8	)	)	PUNCT
bjp-23981	88	9	also	also	ADV
bjp-23981	88	10	showed	show	VERB
bjp-23981	88	11	a	a	DET
bjp-23981	88	12	tpsa	tpsa	NOUN
bjp-23981	88	13	of	of	ADP
bjp-23981	88	14	less	less	ADJ
bjp-23981	88	15	than	than	ADP
bjp-23981	88	16	140	140	NUM
bjp-23981	88	17	å	å	NOUN
bjp-23981	88	18	,	,	PUNCT
bjp-23981	88	19	indicating	indicate	VERB
bjp-23981	88	20	a	a	DET
bjp-23981	88	21	good	good	ADJ
bjp-23981	88	22	permeability	permeability	NOUN
bjp-23981	88	23	of	of	ADP
bjp-23981	88	24	the	the	DET
bjp-23981	88	25	drug	drug	NOUN
bjp-23981	88	26	in	in	ADP
bjp-23981	88	27	the	the	DET
bjp-23981	88	28	cellular	cellular	ADJ
bjp-23981	88	29	plasma	plasma	NOUN
bjp-23981	88	30	membrane	membrane	NOUN
bjp-23981	88	31	.	.	PUNCT
bjp-23981	89	1	most	most	ADJ
bjp-23981	89	2	of	of	ADP
bjp-23981	89	3	the	the	DET
bjp-23981	89	4	clinical	clinical	ADJ
bjp-23981	89	5	available	available	ADJ
bjp-23981	89	6	drugs	drug	NOUN
bjp-23981	89	7	have	have	AUX
bjp-23981	89	8	log	log	NOUN
bjp-23981	89	9	s	s	PUNCT
bjp-23981	89	10	higher	high	ADJ
bjp-23981	89	11	than	than	ADP
bjp-23981	89	12	-4.00	-4.00	NUM
bjp-23981	89	13	.	.	PUNCT
bjp-23981	90	1	the	the	DET
bjp-23981	90	2	compounds	compound	NOUN
bjp-23981	90	3	exhibited	exhibit	VERB
bjp-23981	90	4	a	a	DET
bjp-23981	90	5	log	log	NOUN
bjp-23981	90	6	s	s	NOUN
bjp-23981	90	7	value	value	NOUN
bjp-23981	90	8	greater	great	ADJ
bjp-23981	90	9	than	than	ADP
bjp-23981	90	10	-4.00	-4.00	NUM
bjp-23981	90	11	,	,	PUNCT
bjp-23981	90	12	ranging	range	VERB
bjp-23981	90	13	between	between	ADP
bjp-23981	90	14	-0.81	-0.81	NOUN
bjp-23981	90	15	and	and	CCONJ
bjp-23981	90	16	-3.78	-3.78	PRON
bjp-23981	90	17	(	(	PUNCT
bjp-23981	90	18	except	except	SCONJ
bjp-23981	90	19	compound	compound	NOUN
bjp-23981	90	20	4c	4c	NOUN
bjp-23981	90	21	)	)	PUNCT
bjp-23981	90	22	.	.	PUNCT
bjp-23981	91	1	a	a	DET
bjp-23981	91	2	positive	positive	ADJ
bjp-23981	91	3	value	value	NOUN
bjp-23981	91	4	for	for	ADP
bjp-23981	91	5	druglikeness	druglikeness	NOUN
bjp-23981	91	6	indicates	indicate	VERB
bjp-23981	91	7	that	that	SCONJ
bjp-23981	91	8	the	the	DET
bjp-23981	91	9	compound	compound	NOUN
bjp-23981	91	10	contains	contain	VERB
bjp-23981	91	11	predominantly	predominantly	ADV
bjp-23981	91	12	fragments	fragment	VERB
bjp-23981	91	13	that	that	PRON
bjp-23981	91	14	are	be	AUX
bjp-23981	91	15	often	often	ADV
bjp-23981	91	16	present	present	ADJ
bjp-23981	91	17	in	in	ADP
bjp-23981	91	18	most	most	ADV
bjp-23981	91	19	currently	currently	ADV
bjp-23981	91	20	available	available	ADJ
bjp-23981	91	21	drugs	drug	NOUN
bjp-23981	91	22	.	.	PUNCT
bjp-23981	92	1	only	only	ADV
bjp-23981	92	2	compound	compound	NOUN
bjp-23981	92	3	4c	4c	NOUN
bjp-23981	92	4	,	,	PUNCT
bjp-23981	92	5	the	the	DET
bjp-23981	92	6	3,5dinitrophenyl	3,5dinitrophenyl	NUM
bjp-23981	92	7	derivative	derivative	NOUN
bjp-23981	92	8	was	be	AUX
bjp-23981	92	9	an	an	DET
bjp-23981	92	10	exception	exception	NOUN
bjp-23981	92	11	in	in	ADP
bjp-23981	92	12	the	the	DET
bjp-23981	92	13	in	in	ADP
bjp-23981	92	14	silico	silico	NOUN
bjp-23981	92	15	studies	study	NOUN
bjp-23981	92	16	as	as	SCONJ
bjp-23981	92	17	it	it	PRON
bjp-23981	92	18	was	be	AUX
bjp-23981	92	19	exhibiting	exhibit	VERB
bjp-23981	92	20	a	a	DET
bjp-23981	92	21	tpsa	tpsa	NOUN
bjp-23981	92	22	value	value	NOUN
bjp-23981	92	23	of	of	ADP
bjp-23981	92	24	171	171	NUM
bjp-23981	92	25	å	å	NOUN
bjp-23981	92	26	,	,	PUNCT
bjp-23981	92	27	log	log	NOUN
bjp-23981	92	28	s	s	NOUN
bjp-23981	92	29	value	value	NOUN
bjp-23981	92	30	of	of	ADP
bjp-23981	92	31	-4.24	-4.24	NUM
bjp-23981	92	32	and	and	CCONJ
bjp-23981	92	33	one	one	NUM
bjp-23981	92	34	lipinski	lipinski	PROPN
bjp-23981	92	35	violation	violation	NOUN
bjp-23981	92	36	.	.	PUNCT
bjp-23981	93	1	the	the	DET
bjp-23981	93	2	drug	drug	NOUN
bjp-23981	93	3	score	score	NOUN
bjp-23981	93	4	combines	combine	VERB
bjp-23981	93	5	drug	drug	NOUN
bjp-23981	93	6	-	-	PUNCT
bjp-23981	93	7	likeness	likeness	NOUN
bjp-23981	93	8	,	,	PUNCT
bjp-23981	93	9	lipophilicity	lipophilicity	NOUN
bjp-23981	93	10	,	,	PUNCT
bjp-23981	93	11	solubility	solubility	NOUN
bjp-23981	93	12	,	,	PUNCT
bjp-23981	93	13	molecular	molecular	ADJ
bjp-23981	93	14	weight	weight	NOUN
bjp-23981	93	15	and	and	CCONJ
bjp-23981	93	16	the	the	DET
bjp-23981	93	17	risk	risk	NOUN
bjp-23981	93	18	of	of	ADP
bjp-23981	93	19	toxicity	toxicity	NOUN
bjp-23981	93	20	into	into	ADP
bjp-23981	93	21	a	a	DET
bjp-23981	93	22	single	single	ADJ
bjp-23981	93	23	numerical	numerical	ADJ
bjp-23981	93	24	value	value	NOUN
bjp-23981	93	25	that	that	PRON
bjp-23981	93	26	can	can	AUX
bjp-23981	93	27	be	be	AUX
bjp-23981	93	28	used	use	VERB
bjp-23981	93	29	to	to	PART
bjp-23981	93	30	predict	predict	VERB
bjp-23981	93	31	a	a	DET
bjp-23981	93	32	global	global	ADJ
bjp-23981	93	33	value	value	NOUN
bjp-23981	93	34	for	for	ADP
bjp-23981	93	35	each	each	DET
bjp-23981	93	36	compound	compound	NOUN
bjp-23981	93	37	as	as	ADP
bjp-23981	93	38	a	a	DET
bjp-23981	93	39	potential	potential	ADJ
bjp-23981	93	40	new	new	ADJ
bjp-23981	93	41	drug	drug	NOUN
bjp-23981	93	42	candidate	candidate	NOUN
bjp-23981	93	43	,	,	PUNCT
bjp-23981	93	44	a	a	DET
bjp-23981	93	45	positive	positive	ADJ
bjp-23981	93	46	value	value	NOUN
bjp-23981	93	47	of	of	ADP
bjp-23981	93	48	drug	drug	NOUN
bjp-23981	93	49	scores	score	NOUN
bjp-23981	93	50	indicate	indicate	VERB
bjp-23981	93	51	that	that	SCONJ
bjp-23981	93	52	the	the	DET
bjp-23981	93	53	molecules	molecule	NOUN
bjp-23981	93	54	contain	contain	VERB
bjp-23981	93	55	predominant	predominant	ADJ
bjp-23981	93	56	pharmacophoric	pharmacophoric	ADJ
bjp-23981	93	57	groups	group	NOUN
bjp-23981	93	58	,	,	PUNCT
bjp-23981	93	59	which	which	PRON
bjp-23981	93	60	are	be	AUX
bjp-23981	93	61	often	often	ADV
bjp-23981	93	62	found	find	VERB
bjp-23981	93	63	in	in	ADP
bjp-23981	93	64	pharmaceuticals	pharmaceutical	NOUN
bjp-23981	93	65	.	.	PUNCT
bjp-23981	94	1	the	the	DET
bjp-23981	94	2	results	result	NOUN
bjp-23981	94	3	from	from	ADP
bjp-23981	94	4	the	the	DET
bjp-23981	94	5	calculations	calculation	NOUN
bjp-23981	94	6	show	show	VERB
bjp-23981	94	7	that	that	SCONJ
bjp-23981	94	8	the	the	DET
bjp-23981	94	9	compounds	compound	NOUN
bjp-23981	94	10	gave	give	VERB
bjp-23981	94	11	values	value	NOUN
bjp-23981	94	12	for	for	ADP
bjp-23981	94	13	drug	drug	NOUN
bjp-23981	94	14	-	-	PUNCT
bjp-23981	94	15	likeness	likeness	NOUN
bjp-23981	94	16	between	between	ADP
bjp-23981	94	17	-8.39	-8.39	NOUN
bjp-23981	94	18	to	to	ADP
bjp-23981	94	19	2.7	2.7	NUM
bjp-23981	94	20	.	.	PUNCT
bjp-23981	95	1	all	all	DET
bjp-23981	95	2	compounds	compound	NOUN
bjp-23981	95	3	showed	show	VERB
bjp-23981	95	4	positive	positive	ADJ
bjp-23981	95	5	values	value	NOUN
bjp-23981	95	6	in	in	ADP
bjp-23981	95	7	the	the	DET
bjp-23981	95	8	drug	drug	NOUN
bjp-23981	95	9	score	score	NOUN
bjp-23981	95	10	calculation	calculation	NOUN
bjp-23981	95	11	,	,	PUNCT
bjp-23981	95	12	the	the	DET
bjp-23981	95	13	values	value	NOUN
bjp-23981	95	14	ranged	range	VERB
bjp-23981	95	15	from	from	ADP
bjp-23981	95	16	0.37	0.37	NUM
bjp-23981	95	17	to	to	ADP
bjp-23981	95	18	0.91	0.91	NUM
bjp-23981	95	19	.	.	PUNCT
bjp-23981	96	1	the	the	DET
bjp-23981	96	2	results	result	NOUN
bjp-23981	96	3	highlights	highlight	VERB
bjp-23981	96	4	that	that	SCONJ
bjp-23981	96	5	the	the	DET
bjp-23981	96	6	designed	design	VERB
bjp-23981	96	7	1,3,4	1,3,4	NUM
bjp-23981	96	8	-	-	PUNCT
bjp-23981	96	9	oxadiazole	oxadiazole	NOUN
bjp-23981	96	10	have	have	VERB
bjp-23981	96	11	potential	potential	NOUN
bjp-23981	96	12	as	as	ADP
bjp-23981	96	13	new	new	ADJ
bjp-23981	96	14	drug	drug	NOUN
bjp-23981	96	15	candidates	candidate	NOUN
bjp-23981	96	16	.	.	PUNCT
bjp-23981	97	1	table	table	NOUN
bjp-23981	97	2	ii	ii	PROPN
bjp-23981	97	3	represents	represent	VERB
bjp-23981	97	4	the	the	DET
bjp-23981	97	5	calculated	calculated	ADJ
bjp-23981	97	6	%	%	NOUN
bjp-23981	97	7	abs	ab	NOUN
bjp-23981	97	8	,	,	PUNCT
bjp-23981	97	9	tpsa	tpsa	NOUN
bjp-23981	97	10	and	and	CCONJ
bjp-23981	97	11	lipinski	lipinski	PROPN
bjp-23981	97	12	parameters	parameter	NOUN
bjp-23981	97	13	of	of	ADP
bjp-23981	97	14	the	the	DET
bjp-23981	97	15	synthesized	synthesize	VERB
bjp-23981	97	16	compounds	compound	NOUN
bjp-23981	97	17	.	.	PUNCT
bjp-23981	98	1	molecular	molecular	ADJ
bjp-23981	98	2	docking	docking	NOUN
bjp-23981	98	3	results	result	VERB
bjp-23981	98	4	the	the	DET
bjp-23981	98	5	docking	docking	NOUN
bjp-23981	98	6	study	study	NOUN
bjp-23981	98	7	of	of	ADP
bjp-23981	98	8	the	the	DET
bjp-23981	98	9	1,3,4	1,3,4	NUM
bjp-23981	98	10	-	-	PUNCT
bjp-23981	98	11	oxadiazoles	oxadiazole	NOUN
bjp-23981	98	12	onto	onto	ADP
bjp-23981	98	13	the	the	DET
bjp-23981	98	14	active	active	ADJ
bjp-23981	98	15	site	site	NOUN
bjp-23981	98	16	of	of	ADP
bjp-23981	98	17	the	the	DET
bjp-23981	98	18	enzyme	enzyme	NOUN
bjp-23981	98	19	factor	factor	NOUN
bjp-23981	98	20	xa	xa	PROPN
bjp-23981	98	21	(	(	PUNCT
bjp-23981	98	22	1nfy	1nfy	PROPN
bjp-23981	98	23	)	)	PUNCT
bjp-23981	98	24	were	be	AUX
bjp-23981	98	25	significant	significant	ADJ
bjp-23981	98	26	,	,	PUNCT
bjp-23981	98	27	as	as	SCONJ
bjp-23981	98	28	all	all	DET
bjp-23981	98	29	the	the	DET
bjp-23981	98	30	eleven	eleven	NUM
bjp-23981	98	31	1,3,4	1,3,4	NUM
bjp-23981	98	32	-	-	PUNCT
bjp-23981	98	33	oxadiazoles	oxadiazole	NOUN
bjp-23981	98	34	were	be	AUX
bjp-23981	98	35	exhibiting	exhibit	VERB
bjp-23981	98	36	significantly	significantly	ADV
bjp-23981	98	37	higher	high	ADJ
bjp-23981	98	38	docking	docking	NOUN
bjp-23981	98	39	score	score	NOUN
bjp-23981	98	40	and	and	CCONJ
bjp-23981	98	41	considerable	considerable	ADJ
bjp-23981	98	42	lower	low	ADJ
bjp-23981	98	43	crash	crash	NOUN
bjp-23981	98	44	score	score	NOUN
bjp-23981	98	45	in	in	ADP
bjp-23981	98	46	comparison	comparison	NOUN
bjp-23981	98	47	to	to	ADP
bjp-23981	98	48	the	the	DET
bjp-23981	98	49	cocrystallized	cocrystallize	VERB
bjp-23981	98	50	ligand	ligand	NOUN
bjp-23981	98	51	.	.	PUNCT
bjp-23981	99	1	the	the	DET
bjp-23981	99	2	ligand	ligand	NOUN
bjp-23981	99	3	,	,	PUNCT
bjp-23981	99	4	rpr132747	rpr132747	PROPN
bjp-23981	99	5	exhibited	exhibit	VERB
bjp-23981	99	6	a	a	DET
bjp-23981	99	7	docking	docking	NOUN
bjp-23981	99	8	and	and	CCONJ
bjp-23981	99	9	crash	crash	NOUN
bjp-23981	99	10	score	score	NOUN
bjp-23981	99	11	of	of	ADP
bjp-23981	99	12	6.2033	6.2033	NUM
bjp-23981	99	13	and	and	CCONJ
bjp-23981	99	14	-2.2025	-2.2025	ADJ
bjp-23981	99	15	kcal	kcal	PROPN
bjp-23981	99	16	/	/	SYM
bjp-23981	99	17	m	m	VERB
bjp-23981	99	18	respectively	respectively	ADV
bjp-23981	99	19	,	,	PUNCT
bjp-23981	99	20	with	with	SCONJ
bjp-23981	99	21	the	the	DET
bjp-23981	99	22	main	main	ADJ
bjp-23981	99	23	hydrophobic	hydrophobic	NOUN
bjp-23981	99	24	interactions	interaction	NOUN
bjp-23981	99	25	with	with	ADP
bjp-23981	99	26	the	the	DET
bjp-23981	99	27	surrounding	surround	VERB
bjp-23981	99	28	residues	residue	NOUN
bjp-23981	99	29	cys191	cys191	PROPN
bjp-23981	99	30	,	,	PUNCT
bjp-23981	99	31	gly216	gly216	PROPN
bjp-23981	99	32	,	,	PUNCT
bjp-23981	99	33	ala190	ala190	NOUN
bjp-23981	99	34	and	and	CCONJ
bjp-23981	99	35	trp215	trp215	ADV
bjp-23981	99	36	,	,	PUNCT
bjp-23981	99	37	strongly	strongly	ADV
bjp-23981	99	38	contributed	contribute	VERB
bjp-23981	99	39	to	to	ADP
bjp-23981	99	40	the	the	DET
bjp-23981	99	41	stabilization	stabilization	NOUN
bjp-23981	99	42	.	.	PUNCT
bjp-23981	100	1	the	the	DET
bjp-23981	100	2	hydrogen	hydrogen	NOUN
bjp-23981	100	3	and	and	CCONJ
bjp-23981	100	4	the	the	DET
bjp-23981	100	5	nitrogen	nitrogen	NOUN
bjp-23981	100	6	of	of	ADP
bjp-23981	100	7	the	the	DET
bjp-23981	100	8	imine	imine	NOUN
bjp-23981	100	9	function	function	NOUN
bjp-23981	100	10	exhibited	exhibit	VERB
bjp-23981	100	11	hydrogen	hydrogen	NOUN
bjp-23981	100	12	bond	bond	NOUN
bjp-23981	100	13	interaction	interaction	NOUN
bjp-23981	100	14	with	with	ADP
bjp-23981	100	15	the	the	DET
bjp-23981	100	16	residues	residue	NOUN
bjp-23981	100	17	cys191.h	cys191.h	NOUN
bjp-23981	100	18	and	and	CCONJ
bjp-23981	100	19	cys191.o	cys191.o	PROPN
bjp-23981	100	20	at	at	ADP
bjp-23981	100	21	a	a	DET
bjp-23981	100	22	distance	distance	NOUN
bjp-23981	100	23	of	of	ADP
bjp-23981	100	24	2.887	2.887	NUM
bjp-23981	100	25	and	and	CCONJ
bjp-23981	100	26	1.988	1.988	NUM
bjp-23981	100	27	å	å	NOUN
bjp-23981	100	28	,	,	PUNCT
bjp-23981	100	29	respectively	respectively	ADV
bjp-23981	100	30	.	.	PUNCT
bjp-23981	101	1	the	the	DET
bjp-23981	101	2	proton	proton	NOUN
bjp-23981	101	3	of	of	ADP
bjp-23981	101	4	the	the	DET
bjp-23981	101	5	amino	amino	NOUN
bjp-23981	101	6	group	group	NOUN
bjp-23981	101	7	exhibited	exhibit	VERB
bjp-23981	101	8	hydrogen	hydrogen	NOUN
bjp-23981	101	9	bond	bond	NOUN
bjp-23981	101	10	interaction	interaction	NOUN
bjp-23981	101	11	with	with	ADP
bjp-23981	101	12	the	the	DET
bjp-23981	101	13	residue	residue	NOUN
bjp-23981	101	14	trp215	trp215	ADV
bjp-23981	101	15	at	at	ADP
bjp-23981	101	16	a	a	DET
bjp-23981	101	17	distance	distance	NOUN
bjp-23981	101	18	of	of	ADP
bjp-23981	101	19	2.512	2.512	NUM
bjp-23981	101	20	å	å	NOUN
bjp-23981	101	21	.	.	PUNCT
bjp-23981	102	1	the	the	DET
bjp-23981	102	2	oxygen	oxygen	NOUN
bjp-23981	102	3	of	of	ADP
bjp-23981	102	4	the	the	DET
bjp-23981	102	5	keto	keto	NOUN
bjp-23981	102	6	function	function	NOUN
bjp-23981	102	7	of	of	ADP
bjp-23981	102	8	piperazin-2	piperazin-2	PROPN
bjp-23981	102	9	-	-	SYM
bjp-23981	102	10	one	one	NUM
bjp-23981	102	11	moiety	moiety	NOUN
bjp-23981	102	12	exhibited	exhibit	VERB
bjp-23981	102	13	hydrogen	hydrogen	NOUN
bjp-23981	102	14	bond	bond	NOUN
bjp-23981	102	15	interaction	interaction	NOUN
bjp-23981	102	16	with	with	ADP
bjp-23981	102	17	the	the	DET
bjp-23981	102	18	residue	residue	NOUN
bjp-23981	102	19	gly218	gly218	NOUN
bjp-23981	102	20	at	at	ADP
bjp-23981	102	21	a	a	DET
bjp-23981	102	22	distance	distance	NOUN
bjp-23981	102	23	of	of	ADP
bjp-23981	102	24	2.617	2.617	NUM
bjp-23981	102	25	å	å	NOUN
bjp-23981	102	26	.	.	PUNCT
bjp-23981	103	1	none	none	NOUN
bjp-23981	103	2	of	of	ADP
bjp-23981	103	3	the	the	DET
bjp-23981	103	4	compounds	compound	NOUN
bjp-23981	103	5	exhibited	exhibit	VERB
bjp-23981	103	6	crash	crash	NOUN
bjp-23981	103	7	score	score	NOUN
bjp-23981	103	8	of	of	ADP
bjp-23981	103	9	greater	great	ADJ
bjp-23981	103	10	than	than	ADP
bjp-23981	103	11	-4.5	-4.5	ADP
bjp-23981	103	12	kcal	kcal	PROPN
bjp-23981	103	13	/	/	SYM
bjp-23981	103	14	m.	m.	NOUN
bjp-23981	103	15	a	a	DET
bjp-23981	103	16	crash	crash	NOUN
bjp-23981	103	17	score	score	NOUN
bjp-23981	103	18	greater	great	ADJ
bjp-23981	103	19	than	than	ADP
bjp-23981	103	20	4.5	4.5	NUM
bjp-23981	103	21	kcal	kcal	NOUN
bjp-23981	103	22	/	/	SYM
bjp-23981	103	23	m	m	PROPN
bjp-23981	103	24	,	,	PUNCT
bjp-23981	103	25	indicates	indicate	VERB
bjp-23981	103	26	inappropriate	inappropriate	ADJ
bjp-23981	103	27	penetration	penetration	NOUN
bjp-23981	103	28	of	of	ADP
bjp-23981	103	29	the	the	DET
bjp-23981	103	30	ligand	ligand	NOUN
bjp-23981	103	31	into	into	ADP
bjp-23981	103	32	the	the	DET
bjp-23981	103	33	binding	bind	VERB
bjp-23981	103	34	site	site	NOUN
bjp-23981	103	35	of	of	ADP
bjp-23981	103	36	1cqe	1cqe	NUM
bjp-23981	103	37	resulting	result	VERB
bjp-23981	103	38	in	in	ADP
bjp-23981	103	39	the	the	DET
bjp-23981	103	40	decreased	decrease	VERB
bjp-23981	103	41	forces	force	NOUN
bjp-23981	103	42	of	of	ADP
bjp-23981	103	43	interaction	interaction	NOUN
bjp-23981	103	44	with	with	ADP
bjp-23981	103	45	the	the	DET
bjp-23981	103	46	amino	amino	NOUN
bjp-23981	103	47	acid	acid	NOUN
bjp-23981	103	48	.	.	PUNCT
bjp-23981	104	1	the	the	DET
bjp-23981	104	2	docking	docking	NOUN
bjp-23981	104	3	study	study	NOUN
bjp-23981	104	4	revealed	reveal	VERB
bjp-23981	104	5	that	that	SCONJ
bjp-23981	104	6	the	the	DET
bjp-23981	104	7	1,3,4	1,3,4	NUM
bjp-23981	104	8	-	-	PUNCT
bjp-23981	104	9	oxadiazole	oxadiazole	NOUN
bjp-23981	104	10	derivatives	derivative	NOUN
bjp-23981	104	11	,	,	PUNCT
bjp-23981	104	12	possessed	possess	VERB
bjp-23981	104	13	high	high	ADJ
bjp-23981	104	14	affinity	affinity	NOUN
bjp-23981	104	15	towards	towards	ADP
bjp-23981	104	16	1nfy	1nfy	NUM
bjp-23981	104	17	(	(	PUNCT
bjp-23981	104	18	figure	figure	NOUN
bjp-23981	104	19	3	3	NUM
bjp-23981	104	20	)	)	PUNCT
bjp-23981	104	21	.	.	PUNCT
bjp-23981	105	1	the	the	DET
bjp-23981	105	2	1,3,4	1,3,4	NUM
bjp-23981	105	3	-	-	PUNCT
bjp-23981	105	4	oxadiazoles	oxadiazole	NOUN
bjp-23981	105	5	derived	derive	VERB
bjp-23981	105	6	from	from	ADP
bjp-23981	105	7	benzimi70	benzimi70	PROPN
bjp-23981	105	8	bangladesh	bangladesh	PROPN
bjp-23981	105	9	j	j	PROPN
bjp-23981	105	10	pharmacol	pharmacol	PROPN
bjp-23981	105	11	2016	2016	NUM
bjp-23981	105	12	;	;	PUNCT
bjp-23981	105	13	11	11	NUM
bjp-23981	105	14	:	:	SYM
bjp-23981	105	15	67	67	NUM
bjp-23981	105	16	-	-	SYM
bjp-23981	105	17	74	74	NUM
bjp-23981	105	18	dazole	dazole	NOUN
bjp-23981	105	19	;	;	PUNCT
bjp-23981	105	20	4a-4k	4a-4k	PRON
bjp-23981	105	21	exhibited	exhibit	VERB
bjp-23981	105	22	a	a	DET
bjp-23981	105	23	docking	docking	NOUN
bjp-23981	105	24	score	score	NOUN
bjp-23981	105	25	in	in	ADP
bjp-23981	105	26	the	the	DET
bjp-23981	105	27	range	range	NOUN
bjp-23981	105	28	of	of	ADP
bjp-23981	105	29	6.6126	6.6126	NUM
bjp-23981	105	30	to	to	ADP
bjp-23981	105	31	8.7926	8.7926	NUM
bjp-23981	105	32	kcal	kcal	NOUN
bjp-23981	105	33	/	/	SYM
bjp-23981	105	34	m.	m.	NOUN
bjp-23981	105	35	compound	compound	NOUN
bjp-23981	105	36	4d	4d	NOUN
bjp-23981	105	37	(	(	PUNCT
bjp-23981	105	38	4	4	NUM
bjp-23981	105	39	-	-	PUNCT
bjp-23981	105	40	aminophenyl	aminophenyl	NOUN
bjp-23981	105	41	)	)	PUNCT
bjp-23981	105	42	exhibited	exhibit	VERB
bjp-23981	105	43	the	the	DET
bjp-23981	105	44	highest	high	ADJ
bjp-23981	105	45	docking	docking	NOUN
bjp-23981	105	46	score	score	NOUN
bjp-23981	105	47	(	(	PUNCT
bjp-23981	105	48	8.7926	8.7926	NUM
bjp-23981	105	49	kcal	kcal	NOUN
bjp-23981	105	50	/	/	SYM
bjp-23981	105	51	m	m	NOUN
bjp-23981	105	52	)	)	PUNCT
bjp-23981	105	53	among	among	ADP
bjp-23981	105	54	all	all	DET
bjp-23981	105	55	the	the	DET
bjp-23981	105	56	1,3,4	1,3,4	NUM
bjp-23981	105	57	-	-	PUNCT
bjp-23981	105	58	oxadiazoles	oxadiazole	NOUN
bjp-23981	105	59	and	and	CCONJ
bjp-23981	105	60	compound	compound	VERB
bjp-23981	105	61	4k	4k	NOUN
bjp-23981	105	62	(	(	PUNCT
bjp-23981	105	63	mercapto	mercapto	PROPN
bjp-23981	105	64	)	)	PUNCT
bjp-23981	105	65	with	with	ADP
bjp-23981	105	66	the	the	DET
bjp-23981	105	67	least	least	ADJ
bjp-23981	105	68	docking	docking	ADJ
bjp-23981	105	69	score	score	NOUN
bjp-23981	105	70	(	(	PUNCT
bjp-23981	105	71	6.6126	6.6126	NUM
bjp-23981	105	72	kcal	kcal	NOUN
bjp-23981	105	73	/	/	SYM
bjp-23981	105	74	m	m	NOUN
bjp-23981	105	75	)	)	PUNCT
bjp-23981	105	76	.	.	PUNCT
bjp-23981	106	1	compound	compound	NOUN
bjp-23981	106	2	4d	4d	NOUN
bjp-23981	106	3	(	(	PUNCT
bjp-23981	106	4	4	4	NUM
bjp-23981	106	5	-	-	PUNCT
bjp-23981	106	6	aminophenyl	aminophenyl	NOUN
bjp-23981	106	7	)	)	PUNCT
bjp-23981	106	8	generated	generate	VERB
bjp-23981	106	9	a	a	DET
bjp-23981	106	10	good	good	ADJ
bjp-23981	106	11	docking	docking	NOUN
bjp-23981	106	12	score	score	NOUN
bjp-23981	106	13	of	of	ADP
bjp-23981	106	14	8.7926	8.7926	NUM
bjp-23981	106	15	kcal	kcal	NOUN
bjp-23981	106	16	/	/	SYM
bjp-23981	106	17	m	m	PROPN
bjp-23981	106	18	and	and	CCONJ
bjp-23981	106	19	a	a	DET
bjp-23981	106	20	crash	crash	NOUN
bjp-23981	106	21	score	score	NOUN
bjp-23981	106	22	of	of	ADP
bjp-23981	106	23	-0.9615	-0.9615	ADJ
bjp-23981	106	24	kcal	kcal	NOUN
bjp-23981	106	25	/	/	SYM
bjp-23981	106	26	m.	m.	NOUN
bjp-23981	106	27	the	the	DET
bjp-23981	106	28	hydrogens	hydrogen	NOUN
bjp-23981	106	29	of	of	ADP
bjp-23981	106	30	the	the	DET
bjp-23981	106	31	amino	amino	NOUN
bjp-23981	106	32	group	group	NOUN
bjp-23981	106	33	at	at	ADP
bjp-23981	106	34	position	position	NOUN
bjp-23981	106	35	c2	c2	PROPN
bjp-23981	106	36	of	of	ADP
bjp-23981	106	37	the	the	DET
bjp-23981	106	38	phenyl	phenyl	NOUN
bjp-23981	106	39	moiety	moiety	NOUN
bjp-23981	106	40	were	be	AUX
bjp-23981	106	41	involved	involve	VERB
bjp-23981	106	42	in	in	ADP
bjp-23981	106	43	hydrogen	hydrogen	NOUN
bjp-23981	106	44	bond	bond	NOUN
bjp-23981	106	45	interaction	interaction	NOUN
bjp-23981	106	46	with	with	ADP
bjp-23981	106	47	gly218	gly218	NOUN
bjp-23981	106	48	and	and	CCONJ
bjp-23981	106	49	asp189	asp189	NOUN
bjp-23981	106	50	residues	residue	NOUN
bjp-23981	106	51	at	at	ADP
bjp-23981	106	52	a	a	DET
bjp-23981	106	53	distance	distance	NOUN
bjp-23981	106	54	of	of	ADP
bjp-23981	106	55	2.374	2.374	NUM
bjp-23981	106	56	and	and	CCONJ
bjp-23981	106	57	1.967	1.967	NUM
bjp-23981	106	58	å	å	NOUN
bjp-23981	106	59	,	,	PUNCT
bjp-23981	106	60	respectively	respectively	ADV
bjp-23981	106	61	.	.	PUNCT
bjp-23981	107	1	the	the	DET
bjp-23981	107	2	1h	1h	NUM
bjp-23981	107	3	hydrogen	hydrogen	NOUN
bjp-23981	107	4	of	of	ADP
bjp-23981	107	5	the	the	DET
bjp-23981	107	6	benzimidazole	benzimidazole	ADJ
bjp-23981	107	7	moiety	moiety	NOUN
bjp-23981	107	8	and	and	CCONJ
bjp-23981	107	9	the	the	DET
bjp-23981	107	10	hydrogen	hydrogen	NOUN
bjp-23981	107	11	of	of	ADP
bjp-23981	107	12	the	the	DET
bjp-23981	107	13	amino	amino	NOUN
bjp-23981	107	14	bridge	bridge	NOUN
bjp-23981	107	15	between	between	ADP
bjp-23981	107	16	the	the	DET
bjp-23981	107	17	benzimidazole	benzimidazole	NOUN
bjp-23981	107	18	and	and	CCONJ
bjp-23981	107	19	1,3,4	1,3,4	NUM
bjp-23981	107	20	-	-	PUNCT
bjp-23981	107	21	oxadiazole	oxadiazole	NOUN
bjp-23981	107	22	were	be	AUX
bjp-23981	107	23	involved	involve	VERB
bjp-23981	107	24	in	in	ADP
bjp-23981	107	25	hydrogen	hydrogen	NOUN
bjp-23981	107	26	bond	bond	NOUN
bjp-23981	107	27	interaction	interaction	NOUN
bjp-23981	107	28	with	with	ADP
bjp-23981	107	29	tyr99	tyr99	ADJ
bjp-23981	107	30	residue	residue	NOUN
bjp-23981	107	31	at	at	ADP
bjp-23981	107	32	a	a	DET
bjp-23981	107	33	distance	distance	NOUN
bjp-23981	107	34	of	of	ADP
bjp-23981	107	35	2.034	2.034	NUM
bjp-23981	107	36	and	and	CCONJ
bjp-23981	107	37	2.420	2.420	NUM
bjp-23981	107	38	å	å	NOUN
bjp-23981	107	39	,	,	PUNCT
bjp-23981	107	40	respectively	respectively	ADV
bjp-23981	107	41	.	.	PUNCT
bjp-23981	108	1	while	while	SCONJ
bjp-23981	108	2	,	,	PUNCT
bjp-23981	108	3	the	the	DET
bjp-23981	108	4	nitrogen	nitrogen	NOUN
bjp-23981	108	5	at	at	ADP
bjp-23981	108	6	position	position	NOUN
bjp-23981	108	7	3	3	NUM
bjp-23981	108	8	of	of	ADP
bjp-23981	108	9	the	the	DET
bjp-23981	108	10	benzimidazole	benzimidazole	ADJ
bjp-23981	108	11	moiety	moiety	NOUN
bjp-23981	108	12	was	be	AUX
bjp-23981	108	13	exhibiting	exhibit	VERB
bjp-23981	108	14	hydrogen	hydrogen	NOUN
bjp-23981	108	15	bond	bond	NOUN
bjp-23981	108	16	interaction	interaction	NOUN
bjp-23981	108	17	with	with	ADP
bjp-23981	108	18	ser195	ser195	ADJ
bjp-23981	108	19	residue	residue	NOUN
bjp-23981	108	20	at	at	ADP
bjp-23981	108	21	a	a	DET
bjp-23981	108	22	distance	distance	NOUN
bjp-23981	108	23	of	of	ADP
bjp-23981	108	24	2.083	2.083	NUM
bjp-23981	108	25	å	å	NOUN
bjp-23981	108	26	.	.	PUNCT
bjp-23981	109	1	the	the	DET
bjp-23981	109	2	oxygen	oxygen	NOUN
bjp-23981	109	3	of	of	ADP
bjp-23981	109	4	the	the	DET
bjp-23981	109	5	1,3,4	1,3,4	NUM
bjp-23981	109	6	-	-	PUNCT
bjp-23981	109	7	oxadiazole	oxadiazole	NOUN
bjp-23981	109	8	moiety	moiety	NOUN
bjp-23981	109	9	was	be	AUX
bjp-23981	109	10	involved	involve	VERB
bjp-23981	109	11	in	in	ADP
bjp-23981	109	12	hydrogen	hydrogen	NOUN
bjp-23981	109	13	bond	bond	NOUN
bjp-23981	109	14	interaction	interaction	NOUN
bjp-23981	109	15	with	with	ADP
bjp-23981	109	16	gly216	gly216	PROPN
bjp-23981	109	17	residue	residue	NOUN
bjp-23981	109	18	at	at	ADP
bjp-23981	109	19	a	a	DET
bjp-23981	109	20	distance	distance	NOUN
bjp-23981	109	21	of	of	ADP
bjp-23981	109	22	2.301	2.301	NUM
bjp-23981	109	23	å	å	NOUN
bjp-23981	109	24	.	.	PUNCT
bjp-23981	110	1	all	all	DET
bjp-23981	110	2	the	the	DET
bjp-23981	110	3	1,3,4	1,3,4	NUM
bjp-23981	110	4	-	-	PUNCT
bjp-23981	110	5	oxadiafigure	oxadiafigure	NOUN
bjp-23981	110	6	3	3	NUM
bjp-23981	110	7	:	:	PUNCT
bjp-23981	110	8	energy	energy	NOUN
bjp-23981	110	9	minimized	minimized	ADJ
bjp-23981	110	10	and	and	CCONJ
bjp-23981	110	11	conformationally	conformationally	ADV
bjp-23981	110	12	analyzed	analyze	VERB
bjp-23981	110	13	structures	structure	NOUN
bjp-23981	110	14	aligned	align	VERB
bjp-23981	110	15	against	against	ADP
bjp-23981	110	16	common	common	ADJ
bjp-23981	110	17	atoms	atom	NOUN
bjp-23981	110	18	interacting	interact	VERB
bjp-23981	110	19	with	with	ADP
bjp-23981	110	20	protomol	protomol	PROPN
bjp-23981	110	21	1nfy	1nfy	PROPN
bjp-23981	110	22	table	table	NOUN
bjp-23981	110	23	ii	ii	NOUN
bjp-23981	110	24	predicted	predict	VERB
bjp-23981	110	25	adme	adme	NOUN
bjp-23981	110	26	,	,	PUNCT
bjp-23981	110	27	lipinski	lipinski	PROPN
bjp-23981	110	28	parameters	parameter	NOUN
bjp-23981	110	29	and	and	CCONJ
bjp-23981	110	30	molecular	molecular	ADJ
bjp-23981	110	31	properties	property	NOUN
bjp-23981	110	32	of	of	ADP
bjp-23981	110	33	the	the	DET
bjp-23981	110	34	synthesized	synthesize	VERB
bjp-23981	110	35	compounds	compound	NOUN
bjp-23981	110	36	sl	sl	VERB
bjp-23981	110	37	no	no	INTJ
bjp-23981	110	38	.	.	PUNCT
bjp-23981	111	1	compound	compound	NOUN
bjp-23981	111	2	%	%	NOUN
bjp-23981	111	3	abs	ab	VERB
bjp-23981	111	4	tpsa	tpsa	VERB
bjp-23981	111	5	nrotb	nrotb	PROPN
bjp-23981	111	6	nhba	nhba	PROPN
bjp-23981	111	7	nhbd	nhbd	PROPN
bjp-23981	111	8	mi	mi	PROPN
bjp-23981	111	9	logp	logp	PROPN
bjp-23981	111	10	mol	mol	PROPN
bjp-23981	111	11	.	.	PUNCT
bjp-23981	112	1	weight	weight	NOUN
bjp-23981	112	2	n	n	PROPN
bjp-23981	112	3	violations	violation	NOUN
bjp-23981	112	4	logs	log	VERB
bjp-23981	112	5	drug	drug	NOUN
bjp-23981	112	6	likeness	likeness	NOUN
bjp-23981	112	7	drug	drug	NOUN
bjp-23981	112	8	score	score	NOUN
bjp-23981	112	9	1	1	NUM
bjp-23981	112	10	4a	4a	NOUN
bjp-23981	112	11	82	82	NUM
bjp-23981	112	12	79.6	79.6	NUM
bjp-23981	112	13	5	5	NUM
bjp-23981	112	14	6	6	NUM
bjp-23981	112	15	2	2	NUM
bjp-23981	112	16	1.9	1.9	NUM
bjp-23981	112	17	305.3	305.3	NUM
bjp-23981	112	18	0	0	NUM
bjp-23981	112	19	-3.3	-3.3	PROPN
bjp-23981	112	20	2.5	2.5	NUM
bjp-23981	112	21	0.8	0.8	NUM
bjp-23981	112	22	2	2	NUM
bjp-23981	112	23	4b	4b	X
bjp-23981	112	24	66	66	NUM
bjp-23981	112	25	125.5	125.5	NUM
bjp-23981	112	26	6	6	NUM
bjp-23981	112	27	9	9	NUM
bjp-23981	112	28	2	2	NUM
bjp-23981	112	29	1.8	1.8	NUM
bjp-23981	112	30	350.3	350.3	NUM
bjp-23981	112	31	0	0	NUM
bjp-23981	112	32	-3.8	-3.8	PROPN
bjp-23981	112	33	-5.2	-5.2	NOUN
bjp-23981	112	34	0.4	0.4	NUM
bjp-23981	112	35	3	3	NUM
bjp-23981	112	36	4c	4c	NOUN
bjp-23981	112	37	50	50	NUM
bjp-23981	112	38	171.3	171.3	NUM
bjp-23981	112	39	7	7	NUM
bjp-23981	112	40	12	12	NUM
bjp-23981	112	41	2	2	NUM
bjp-23981	112	42	1.8	1.8	NUM
bjp-23981	112	43	395.3	395.3	NUM
bjp-23981	112	44	1	1	NUM
bjp-23981	112	45	-4.2	-4.2	NOUN
bjp-23981	112	46	-8.4	-8.4	NOUN
bjp-23981	112	47	0.4	0.4	NUM
bjp-23981	112	48	4	4	NUM
bjp-23981	112	49	4d	4d	NOUN
bjp-23981	112	50	73	73	NUM
bjp-23981	112	51	105.7	105.7	NUM
bjp-23981	112	52	5	5	NUM
bjp-23981	112	53	7	7	NUM
bjp-23981	112	54	4	4	NUM
bjp-23981	112	55	1.4	1.4	NUM
bjp-23981	112	56	320.4	320.4	NUM
bjp-23981	112	57	0	0	NUM
bjp-23981	112	58	-3.4	-3.4	NOUN
bjp-23981	112	59	-0.3	-0.3	PROPN
bjp-23981	112	60	0.6	0.6	NUM
bjp-23981	112	61	5	5	NUM
bjp-23981	112	62	4e	4e	NOUN
bjp-23981	112	63	73	73	NUM
bjp-23981	112	64	105.7	105.7	NUM
bjp-23981	112	65	5	5	NUM
bjp-23981	112	66	7	7	NUM
bjp-23981	112	67	4	4	NUM
bjp-23981	112	68	1.0	1.0	NUM
bjp-23981	112	69	320.4	320.4	NUM
bjp-23981	112	70	0	0	NUM
bjp-23981	112	71	-3.4	-3.4	NOUN
bjp-23981	112	72	1.0	1.0	NUM
bjp-23981	112	73	0.7	0.7	NUM
bjp-23981	112	74	6	6	NUM
bjp-23981	112	75	4f	4f	NUM
bjp-23981	112	76	75	75	NUM
bjp-23981	112	77	99.9	99.9	NUM
bjp-23981	112	78	5	5	NUM
bjp-23981	112	79	7	7	NUM
bjp-23981	112	80	3	3	NUM
bjp-23981	112	81	1.7	1.7	NUM
bjp-23981	112	82	321.3	321.3	NUM
bjp-23981	112	83	0	0	NUM
bjp-23981	112	84	-3.0	-3.0	X
bjp-23981	112	85	2.0	2.0	NUM
bjp-23981	112	86	0.8	0.8	NUM
bjp-23981	112	87	7	7	NUM
bjp-23981	112	88	4	4	NUM
bjp-23981	112	89	g	g	NOUN
bjp-23981	112	90	75	75	NUM
bjp-23981	112	91	99.9	99.9	NUM
bjp-23981	112	92	5	5	NUM
bjp-23981	112	93	7	7	NUM
bjp-23981	112	94	3	3	NUM
bjp-23981	112	95	1.4	1.4	NUM
bjp-23981	112	96	321.3	321.3	NUM
bjp-23981	112	97	0	0	NUM
bjp-23981	112	98	-3.0	-3.0	NUM
bjp-23981	112	99	1.0	1.0	NUM
bjp-23981	112	100	0.8	0.8	NUM
bjp-23981	112	101	8	8	NUM
bjp-23981	112	102	4h	4h	NUM
bjp-23981	112	103	77	77	NUM
bjp-23981	112	104	92.5	92.5	NUM
bjp-23981	112	105	5	5	NUM
bjp-23981	112	106	7	7	NUM
bjp-23981	112	107	2	2	NUM
bjp-23981	112	108	0.8	0.8	NUM
bjp-23981	112	109	306.3	306.3	NUM
bjp-23981	112	110	0	0	NUM
bjp-23981	113	1	-2.5	-2.5	PROPN
bjp-23981	113	2	2.7	2.7	NUM
bjp-23981	113	3	0.9	0.9	NUM
bjp-23981	113	4	9	9	NUM
bjp-23981	113	5	4i	4i	NOUN
bjp-23981	113	6	82	82	NUM
bjp-23981	114	1	79.6	79.6	NUM
bjp-23981	114	2	4	4	NUM
bjp-23981	114	3	6	6	NUM
bjp-23981	114	4	2	2	NUM
bjp-23981	114	5	0	0	NUM
bjp-23981	114	6	229.2	229.2	NUM
bjp-23981	114	7	0	0	NUM
bjp-23981	114	8	-1.2	-1.2	NUM
bjp-23981	114	9	1.9	1.9	NUM
bjp-23981	114	10	0.9	0.9	NUM
bjp-23981	114	11	10	10	NUM
bjp-23981	114	12	4j	4j	NOUN
bjp-23981	114	13	82	82	NUM
bjp-23981	114	14	79.6	79.6	NUM
bjp-23981	114	15	4	4	NUM
bjp-23981	114	16	6	6	NUM
bjp-23981	114	17	2	2	NUM
bjp-23981	114	18	-0.5	-0.5	NUM
bjp-23981	114	19	243.3	243.3	NUM
bjp-23981	114	20	0	0	NUM
bjp-23981	114	21	-0.8	-0.8	NUM
bjp-23981	114	22	1.9	1.9	NUM
bjp-23981	114	23	0.9	0.9	NUM
bjp-23981	114	24	11	11	NUM
bjp-23981	114	25	4k	4k	NUM
bjp-23981	114	26	82	82	NUM
bjp-23981	114	27	79.6	79.6	NUM
bjp-23981	114	28	4	4	NUM
bjp-23981	114	29	6	6	NUM
bjp-23981	114	30	2	2	NUM
bjp-23981	114	31	0.5	0.5	NUM
bjp-23981	114	32	261.3	261.3	NUM
bjp-23981	114	33	0	0	NUM
bjp-23981	114	34	-2.1	-2.1	NUM
bjp-23981	114	35	-0.4	-0.4	NUM
bjp-23981	114	36	0.7	0.7	NUM
bjp-23981	114	37	bangladesh	bangladesh	NOUN
bjp-23981	114	38	j	j	PROPN
bjp-23981	114	39	pharmacol	pharmacol	PROPN
bjp-23981	114	40	2016	2016	NUM
bjp-23981	114	41	;	;	PUNCT
bjp-23981	114	42	11	11	NUM
bjp-23981	114	43	:	:	SYM
bjp-23981	114	44	67	67	NUM
bjp-23981	114	45	-	-	SYM
bjp-23981	114	46	74	74	NUM
bjp-23981	114	47	71	71	NUM
bjp-23981	114	48	zoles	zole	NOUN
bjp-23981	114	49	generated	generate	VERB
bjp-23981	114	50	crash	crash	NOUN
bjp-23981	114	51	score	score	NOUN
bjp-23981	114	52	less	less	ADV
bjp-23981	114	53	than	than	ADP
bjp-23981	114	54	-4.5	-4.5	ADP
bjp-23981	114	55	kcal	kcal	PROPN
bjp-23981	114	56	/	/	SYM
bjp-23981	114	57	m	m	VERB
bjp-23981	114	58	indicating	indicate	VERB
bjp-23981	114	59	that	that	SCONJ
bjp-23981	114	60	the	the	DET
bjp-23981	114	61	1,3,4	1,3,4	NUM
bjp-23981	114	62	-	-	PUNCT
bjp-23981	114	63	oxadiazoles	oxadiazole	NOUN
bjp-23981	114	64	exhibited	exhibit	VERB
bjp-23981	114	65	appropriate	appropriate	ADJ
bjp-23981	114	66	penetration	penetration	NOUN
bjp-23981	114	67	onto	onto	ADP
bjp-23981	114	68	the	the	DET
bjp-23981	114	69	binding	bind	VERB
bjp-23981	114	70	site	site	NOUN
bjp-23981	114	71	of	of	ADP
bjp-23981	114	72	1nfy	1nfy	PROPN
bjp-23981	114	73	.	.	PUNCT
bjp-23981	115	1	the	the	DET
bjp-23981	115	2	crash	crash	NOUN
bjp-23981	115	3	score	score	NOUN
bjp-23981	115	4	of	of	ADP
bjp-23981	115	5	the	the	DET
bjp-23981	115	6	all	all	PRON
bjp-23981	115	7	designed	design	VERB
bjp-23981	115	8	1,3,4	1,3,4	NUM
bjp-23981	115	9	-	-	PUNCT
bjp-23981	115	10	oxadiazoles	oxadiazole	NOUN
bjp-23981	115	11	were	be	AUX
bjp-23981	115	12	in	in	ADP
bjp-23981	115	13	the	the	DET
bjp-23981	115	14	range	range	NOUN
bjp-23981	115	15	of	of	ADP
bjp-23981	115	16	-0.2259	-0.2259	NOUN
bjp-23981	115	17	to	to	PART
bjp-23981	115	18	-1.6941	-1.6941	VERB
bjp-23981	115	19	kcal	kcal	PROPN
bjp-23981	115	20	/	/	SYM
bjp-23981	115	21	m	m	NOUN
bjp-23981	115	22	significantly	significantly	ADV
bjp-23981	115	23	less	less	ADJ
bjp-23981	115	24	than	than	ADP
bjp-23981	115	25	that	that	PRON
bjp-23981	115	26	of	of	ADP
bjp-23981	115	27	the	the	DET
bjp-23981	115	28	control	control	PROPN
bjp-23981	115	29	ligand	ligand	PROPN
bjp-23981	115	30	rpr132747	rpr132747	NOUN
bjp-23981	115	31	(	(	PUNCT
bjp-23981	115	32	-2.2025	-2.2025	ADJ
bjp-23981	115	33	kcal	kcal	PROPN
bjp-23981	115	34	/	/	SYM
bjp-23981	115	35	m	m	PROPN
bjp-23981	115	36	)	)	PUNCT
bjp-23981	115	37	.	.	PUNCT
bjp-23981	116	1	followed	follow	VERB
bjp-23981	116	2	by	by	ADP
bjp-23981	116	3	4d	4d	NUM
bjp-23981	116	4	,	,	PUNCT
bjp-23981	116	5	compound	compound	NOUN
bjp-23981	116	6	4c	4c	NOUN
bjp-23981	116	7	(	(	PUNCT
bjp-23981	116	8	3,5	3,5	NUM
bjp-23981	116	9	-	-	PUNCT
bjp-23981	116	10	dinitrophenyl	dinitrophenyl	NOUN
bjp-23981	116	11	)	)	PUNCT
bjp-23981	116	12	generated	generate	VERB
bjp-23981	116	13	a	a	DET
bjp-23981	116	14	docking	docking	NOUN
bjp-23981	116	15	score	score	NOUN
bjp-23981	116	16	of	of	ADP
bjp-23981	116	17	8.3500	8.3500	NUM
bjp-23981	116	18	kcal	kcal	NOUN
bjp-23981	116	19	/	/	SYM
bjp-23981	116	20	m	m	PROPN
bjp-23981	116	21	,	,	PUNCT
bjp-23981	116	22	the	the	DET
bjp-23981	116	23	1h	1h	NUM
bjp-23981	116	24	of	of	ADP
bjp-23981	116	25	the	the	DET
bjp-23981	116	26	benzimidazole	benzimidazole	ADJ
bjp-23981	116	27	moiety	moiety	NOUN
bjp-23981	116	28	showed	show	VERB
bjp-23981	116	29	hydrogen	hydrogen	NOUN
bjp-23981	116	30	bond	bond	NOUN
bjp-23981	116	31	interaction	interaction	NOUN
bjp-23981	116	32	with	with	ADP
bjp-23981	116	33	ser214	ser214	ADJ
bjp-23981	116	34	and	and	CCONJ
bjp-23981	116	35	ser195	ser195	ADJ
bjp-23981	116	36	residues	residue	NOUN
bjp-23981	116	37	at	at	ADP
bjp-23981	116	38	a	a	DET
bjp-23981	116	39	distance	distance	NOUN
bjp-23981	116	40	of	of	ADP
bjp-23981	116	41	2.626	2.626	NUM
bjp-23981	116	42	and	and	CCONJ
bjp-23981	116	43	2.723	2.723	NUM
bjp-23981	116	44	å	å	NOUN
bjp-23981	116	45	,	,	PUNCT
bjp-23981	116	46	respectively	respectively	ADV
bjp-23981	116	47	.	.	PUNCT
bjp-23981	117	1	the	the	DET
bjp-23981	117	2	nitrogen	nitrogen	NOUN
bjp-23981	117	3	at	at	ADP
bjp-23981	117	4	position	position	NOUN
bjp-23981	117	5	3	3	NUM
bjp-23981	117	6	and	and	CCONJ
bjp-23981	117	7	4	4	NUM
bjp-23981	117	8	were	be	AUX
bjp-23981	117	9	involved	involve	VERB
bjp-23981	117	10	in	in	ADP
bjp-23981	117	11	hydrogen	hydrogen	NOUN
bjp-23981	117	12	bond	bond	NOUN
bjp-23981	117	13	interaction	interaction	NOUN
bjp-23981	117	14	with	with	ADP
bjp-23981	117	15	ser195	ser195	ADJ
bjp-23981	117	16	residue	residue	NOUN
bjp-23981	117	17	at	at	ADP
bjp-23981	117	18	a	a	DET
bjp-23981	117	19	distance	distance	NOUN
bjp-23981	117	20	of	of	ADP
bjp-23981	117	21	1.981	1.981	NUM
bjp-23981	117	22	and	and	CCONJ
bjp-23981	117	23	2.695	2.695	NUM
bjp-23981	117	24	å	å	NOUN
bjp-23981	117	25	,	,	PUNCT
bjp-23981	117	26	respectively	respectively	ADV
bjp-23981	117	27	.	.	PUNCT
bjp-23981	118	1	compound	compound	VERB
bjp-23981	118	2	4	4	NUM
bjp-23981	118	3	g	g	NOUN
bjp-23981	118	4	(	(	PUNCT
bjp-23981	118	5	4	4	NUM
bjp-23981	118	6	-	-	PUNCT
bjp-23981	118	7	hydroxyphenyl	hydroxyphenyl	NOUN
bjp-23981	118	8	)	)	PUNCT
bjp-23981	118	9	exhibited	exhibit	VERB
bjp-23981	118	10	a	a	DET
bjp-23981	118	11	docking	docking	NOUN
bjp-23981	118	12	score	score	NOUN
bjp-23981	118	13	of	of	ADP
bjp-23981	118	14	8.1578	8.1578	NUM
bjp-23981	118	15	kcal	kcal	NOUN
bjp-23981	118	16	/	/	SYM
bjp-23981	118	17	m	m	PROPN
bjp-23981	118	18	,	,	PUNCT
bjp-23981	118	19	the	the	DET
bjp-23981	118	20	oxygen	oxygen	NOUN
bjp-23981	118	21	of	of	ADP
bjp-23981	118	22	1,3,4	1,3,4	NUM
bjp-23981	118	23	-	-	PUNCT
bjp-23981	118	24	oxadiazole	oxadiazole	NOUN
bjp-23981	118	25	was	be	AUX
bjp-23981	118	26	involved	involve	VERB
bjp-23981	118	27	in	in	ADP
bjp-23981	118	28	hydrogen	hydrogen	NOUN
bjp-23981	118	29	bond	bond	NOUN
bjp-23981	118	30	interaction	interaction	NOUN
bjp-23981	118	31	with	with	ADP
bjp-23981	118	32	gly216	gly216	PROPN
bjp-23981	118	33	residue	residue	NOUN
bjp-23981	118	34	at	at	ADP
bjp-23981	118	35	a	a	DET
bjp-23981	118	36	distance	distance	NOUN
bjp-23981	118	37	of	of	ADP
bjp-23981	118	38	1.894å	1.894å	NOUN
bjp-23981	118	39	,	,	PUNCT
bjp-23981	118	40	the	the	DET
bjp-23981	118	41	hydrogen	hydrogen	NOUN
bjp-23981	118	42	of	of	ADP
bjp-23981	118	43	1h	1h	NUM
bjp-23981	118	44	benzimidazole	benzimidazole	PROPN
bjp-23981	118	45	moiety	moiety	NOUN
bjp-23981	118	46	showed	show	VERB
bjp-23981	118	47	hydrogen	hydrogen	NOUN
bjp-23981	118	48	bond	bond	NOUN
bjp-23981	118	49	interaction	interaction	NOUN
bjp-23981	118	50	with	with	ADP
bjp-23981	118	51	gly216	gly216	PROPN
bjp-23981	118	52	residue	residue	NOUN
bjp-23981	118	53	at	at	ADP
bjp-23981	118	54	a	a	DET
bjp-23981	118	55	distance	distance	NOUN
bjp-23981	118	56	of	of	ADP
bjp-23981	118	57	1.869å	1.869å	NUM
bjp-23981	118	58	,	,	PUNCT
bjp-23981	118	59	the	the	DET
bjp-23981	118	60	oxygen	oxygen	NOUN
bjp-23981	118	61	and	and	CCONJ
bjp-23981	118	62	the	the	DET
bjp-23981	118	63	hydrogen	hydrogen	NOUN
bjp-23981	118	64	of	of	ADP
bjp-23981	118	65	the	the	DET
bjp-23981	118	66	hydroxy	hydroxy	PROPN
bjp-23981	118	67	group	group	NOUN
bjp-23981	118	68	at	at	ADP
bjp-23981	118	69	position	position	NOUN
bjp-23981	118	70	c4	c4	NOUN
bjp-23981	118	71	of	of	ADP
bjp-23981	118	72	the	the	DET
bjp-23981	118	73	phenyl	phenyl	NOUN
bjp-23981	118	74	moiety	moiety	NOUN
bjp-23981	118	75	were	be	AUX
bjp-23981	118	76	exhibiting	exhibit	VERB
bjp-23981	118	77	hydrogen	hydrogen	NOUN
bjp-23981	118	78	bond	bond	NOUN
bjp-23981	118	79	interaction	interaction	NOUN
bjp-23981	118	80	with	with	ADP
bjp-23981	118	81	cys191	cys191	PROPN
bjp-23981	118	82	residue	residue	NOUN
bjp-23981	118	83	at	at	ADP
bjp-23981	118	84	a	a	DET
bjp-23981	118	85	distance	distance	NOUN
bjp-23981	118	86	of	of	ADP
bjp-23981	118	87	2.703	2.703	NUM
bjp-23981	118	88	and	and	CCONJ
bjp-23981	118	89	1.966	1.966	NUM
bjp-23981	118	90	å	å	PROPN
bjp-23981	118	91	,	,	PUNCT
bjp-23981	118	92	respectively	respectively	ADV
bjp-23981	118	93	.	.	PUNCT
bjp-23981	119	1	the	the	DET
bjp-23981	119	2	1h	1h	NOUN
bjp-23981	119	3	of	of	ADP
bjp-23981	119	4	the	the	DET
bjp-23981	119	5	benzimidazole	benzimidazole	NOUN
bjp-23981	119	6	and	and	CCONJ
bjp-23981	119	7	hydrogen	hydrogen	NOUN
bjp-23981	119	8	of	of	ADP
bjp-23981	119	9	the	the	DET
bjp-23981	119	10	amino	amino	NOUN
bjp-23981	119	11	bridge	bridge	NOUN
bjp-23981	119	12	were	be	AUX
bjp-23981	119	13	exhibiting	exhibit	VERB
bjp-23981	119	14	hydrogen	hydrogen	NOUN
bjp-23981	119	15	bond	bond	NOUN
bjp-23981	119	16	interaction	interaction	NOUN
bjp-23981	119	17	with	with	ADP
bjp-23981	119	18	ser195	ser195	NOUN
bjp-23981	119	19	and	and	CCONJ
bjp-23981	119	20	gly216	gly216	PROPN
bjp-23981	119	21	residues	residue	NOUN
bjp-23981	119	22	respectively	respectively	ADV
bjp-23981	119	23	.	.	PUNCT
bjp-23981	120	1	the	the	DET
bjp-23981	120	2	oxygen	oxygen	NOUN
bjp-23981	120	3	and	and	CCONJ
bjp-23981	120	4	the	the	DET
bjp-23981	120	5	nitrogens	nitrogen	NOUN
bjp-23981	120	6	of	of	ADP
bjp-23981	120	7	1,3,4	1,3,4	NUM
bjp-23981	120	8	-	-	PUNCT
bjp-23981	120	9	oxadiazole	oxadiazole	NOUN
bjp-23981	120	10	were	be	AUX
bjp-23981	120	11	exhibiting	exhibit	VERB
bjp-23981	120	12	hydrogen	hydrogen	NOUN
bjp-23981	120	13	bond	bond	NOUN
bjp-23981	120	14	interaction	interaction	NOUN
bjp-23981	120	15	with	with	ADP
bjp-23981	120	16	gly216	gly216	PROPN
bjp-23981	120	17	and	and	CCONJ
bjp-23981	120	18	ser195	ser195	ADJ
bjp-23981	120	19	residues	residue	NOUN
bjp-23981	120	20	,	,	PUNCT
bjp-23981	120	21	respectively	respectively	ADV
bjp-23981	120	22	.	.	PUNCT
bjp-23981	121	1	these	these	PRON
bjp-23981	121	2	were	be	AUX
bjp-23981	121	3	the	the	DET
bjp-23981	121	4	common	common	ADJ
bjp-23981	121	5	and	and	CCONJ
bjp-23981	121	6	major	major	ADJ
bjp-23981	121	7	interaction	interaction	NOUN
bjp-23981	121	8	exhibited	exhibit	VERB
bjp-23981	121	9	by	by	ADP
bjp-23981	121	10	4a-4k	4a-4k	DET
bjp-23981	121	11	series	series	NOUN
bjp-23981	121	12	of	of	ADP
bjp-23981	121	13	1,3,4oxadiazoles	1,3,4oxadiazoles	NUM
bjp-23981	121	14	.	.	PUNCT
bjp-23981	122	1	the	the	DET
bjp-23981	122	2	other	other	ADJ
bjp-23981	122	3	1,3,4	1,3,4	NUM
bjp-23981	122	4	-	-	PUNCT
bjp-23981	122	5	oxadiazoles	oxadiazole	NOUN
bjp-23981	122	6	with	with	ADP
bjp-23981	122	7	docking	dock	VERB
bjp-23981	122	8	score	score	NOUN
bjp-23981	122	9	>	>	X
bjp-23981	122	10	7	7	NUM
bjp-23981	122	11	kcal	kcal	NOUN
bjp-23981	122	12	/	/	SYM
bjp-23981	122	13	m	m	PROPN
bjp-23981	122	14	were	be	AUX
bjp-23981	122	15	4d	4d	NUM
bjp-23981	122	16	(	(	PUNCT
bjp-23981	122	17	4	4	NUM
bjp-23981	122	18	-	-	PUNCT
bjp-23981	122	19	aminophenyl	aminophenyl	NOUN
bjp-23981	122	20	)	)	PUNCT
bjp-23981	122	21	,	,	PUNCT
bjp-23981	122	22	4j	4j	NOUN
bjp-23981	122	23	(	(	PUNCT
bjp-23981	122	24	pyridin3	pyridin3	NOUN
bjp-23981	122	25	-	-	NOUN
bjp-23981	122	26	yl	yl	NOUN
bjp-23981	122	27	)	)	PUNCT
bjp-23981	122	28	,	,	PUNCT
bjp-23981	122	29	4	4	NUM
bjp-23981	122	30	g	g	NOUN
bjp-23981	122	31	(	(	PUNCT
bjp-23981	122	32	2	2	NUM
bjp-23981	122	33	-	-	PUNCT
bjp-23981	122	34	hydroxyphenyl	hydroxyphenyl	NOUN
bjp-23981	122	35	)	)	PUNCT
bjp-23981	122	36	,	,	PUNCT
bjp-23981	122	37	4i	4i	NUM
bjp-23981	122	38	(	(	PUNCT
bjp-23981	122	39	methyl	methyl	NOUN
bjp-23981	122	40	)	)	PUNCT
bjp-23981	122	41	,	,	PUNCT
bjp-23981	122	42	4b	4b	X
bjp-23981	122	43	(	(	PUNCT
bjp-23981	122	44	2	2	NUM
bjp-23981	122	45	-	-	PUNCT
bjp-23981	122	46	nitrophenyl	nitrophenyl	NOUN
bjp-23981	122	47	)	)	PUNCT
bjp-23981	122	48	and	and	CCONJ
bjp-23981	122	49	4a	4a	NUM
bjp-23981	122	50	(	(	PUNCT
bjp-23981	122	51	phenyl	phenyl	NOUN
bjp-23981	122	52	)	)	PUNCT
bjp-23981	122	53	exhibiting	exhibit	VERB
bjp-23981	122	54	a	a	DET
bjp-23981	122	55	docking	docking	NOUN
bjp-23981	122	56	score	score	NOUN
bjp-23981	122	57	of	of	ADP
bjp-23981	122	58	7.8387	7.8387	NUM
bjp-23981	122	59	,	,	PUNCT
bjp-23981	122	60	7.7295	7.7295	NUM
bjp-23981	122	61	,	,	PUNCT
bjp-23981	122	62	7.4938	7.4938	NUM
bjp-23981	122	63	,	,	PUNCT
bjp-23981	122	64	7.4188	7.4188	NUM
bjp-23981	122	65	,	,	PUNCT
bjp-23981	122	66	7.3991	7.3991	NUM
bjp-23981	122	67	and	and	CCONJ
bjp-23981	122	68	7.164	7.164	NUM
bjp-23981	122	69	kcal	kcal	NOUN
bjp-23981	122	70	/	/	SYM
bjp-23981	122	71	m	m	PROPN
bjp-23981	122	72	,	,	PUNCT
bjp-23981	122	73	respectively	respectively	ADV
bjp-23981	122	74	.	.	PUNCT
bjp-23981	123	1	the	the	DET
bjp-23981	123	2	docking	dock	VERB
bjp-23981	123	3	score	score	NOUN
bjp-23981	123	4	of	of	ADP
bjp-23981	123	5	1,3,4	1,3,4	NUM
bjp-23981	123	6	-	-	NOUN
bjp-23981	123	7	oxadiazoles	oxadiazole	NOUN
bjp-23981	123	8	;	;	PUNCT
bjp-23981	123	9	4a4k	4a4k	NOUN
bjp-23981	123	10	along	along	ADP
bjp-23981	123	11	with	with	ADP
bjp-23981	123	12	their	their	PRON
bjp-23981	123	13	crash	crash	NOUN
bjp-23981	123	14	score	score	NOUN
bjp-23981	123	15	and	and	CCONJ
bjp-23981	123	16	polar	polar	ADJ
bjp-23981	123	17	score	score	NOUN
bjp-23981	123	18	are	be	AUX
bjp-23981	123	19	presented	present	VERB
bjp-23981	123	20	in	in	ADP
bjp-23981	123	21	table	table	NOUN
bjp-23981	123	22	iii	iii	PROPN
bjp-23981	123	23	.	.	PUNCT
bjp-23981	123	24	thrombolytic	thrombolytic	ADJ
bjp-23981	123	25	activity	activity	NOUN
bjp-23981	123	26	the	the	DET
bjp-23981	123	27	newly	newly	ADV
bjp-23981	123	28	synthesized	synthesize	VERB
bjp-23981	123	29	1,3,4	1,3,4	NUM
bjp-23981	123	30	-	-	PUNCT
bjp-23981	123	31	oxadiazole	oxadiazole	NOUN
bjp-23981	123	32	derivatives	derivative	NOUN
bjp-23981	123	33	4a4k	4a4k	NOUN
bjp-23981	123	34	were	be	AUX
bjp-23981	123	35	evaluated	evaluate	VERB
bjp-23981	123	36	for	for	ADP
bjp-23981	123	37	in	in	ADP
bjp-23981	123	38	vitro	vitro	X
bjp-23981	123	39	thrombolytic	thrombolytic	ADJ
bjp-23981	123	40	activity	activity	NOUN
bjp-23981	123	41	by	by	ADP
bjp-23981	123	42	clot	clot	NOUN
bjp-23981	123	43	lysis	lysis	NOUN
bjp-23981	123	44	study	study	NOUN
bjp-23981	123	45	.	.	PUNCT
bjp-23981	124	1	the	the	DET
bjp-23981	124	2	magnitude	magnitude	NOUN
bjp-23981	124	3	of	of	ADP
bjp-23981	124	4	the	the	DET
bjp-23981	124	5	compounds	compound	NOUN
bjp-23981	124	6	activity	activity	NOUN
bjp-23981	124	7	was	be	AUX
bjp-23981	124	8	determined	determine	VERB
bjp-23981	124	9	in	in	ADP
bjp-23981	124	10	comparison	comparison	NOUN
bjp-23981	124	11	with	with	ADP
bjp-23981	124	12	the	the	DET
bjp-23981	124	13	thrombolytic	thrombolytic	ADJ
bjp-23981	124	14	activity	activity	NOUN
bjp-23981	124	15	of	of	ADP
bjp-23981	124	16	streptokinase	streptokinase	PROPN
bjp-23981	124	17	.	.	PUNCT
bjp-23981	125	1	the	the	DET
bjp-23981	125	2	mean	mean	ADJ
bjp-23981	125	3	ec50	ec50	PROPN
bjp-23981	125	4	values	value	NOUN
bjp-23981	125	5	of	of	ADP
bjp-23981	125	6	the	the	DET
bjp-23981	125	7	tested	test	VERB
bjp-23981	125	8	compounds	compound	NOUN
bjp-23981	125	9	were	be	AUX
bjp-23981	125	10	in	in	ADP
bjp-23981	125	11	the	the	DET
bjp-23981	125	12	range	range	NOUN
bjp-23981	125	13	of	of	ADP
bjp-23981	125	14	74.8	74.8	NUM
bjp-23981	125	15	to	to	PART
bjp-23981	125	16	16.2	16.2	NUM
bjp-23981	125	17	µm	µm	NOUN
bjp-23981	125	18	.	.	PUNCT
bjp-23981	126	1	the	the	DET
bjp-23981	126	2	mean	mean	ADJ
bjp-23981	126	3	percentage	percentage	NOUN
bjp-23981	126	4	clot	clot	NOUN
bjp-23981	126	5	lysis	lysis	NOUN
bjp-23981	126	6	values	value	NOUN
bjp-23981	126	7	±	±	NUM
bjp-23981	126	8	sem	sem	NOUN
bjp-23981	126	9	of	of	ADP
bjp-23981	126	10	tested	test	VERB
bjp-23981	126	11	compounds	compound	NOUN
bjp-23981	126	12	4a-4k	4a-4k	X
bjp-23981	126	13	at	at	ADP
bjp-23981	126	14	the	the	DET
bjp-23981	126	15	different	different	ADJ
bjp-23981	126	16	test	test	NOUN
bjp-23981	126	17	strength	strength	NOUN
bjp-23981	126	18	and	and	CCONJ
bjp-23981	126	19	the	the	DET
bjp-23981	126	20	mean	mean	ADJ
bjp-23981	126	21	ec50	ec50	PROPN
bjp-23981	126	22	values	value	NOUN
bjp-23981	126	23	±	±	NUM
bjp-23981	126	24	sem	sem	NOUN
bjp-23981	126	25	are	be	AUX
bjp-23981	126	26	presented	present	VERB
bjp-23981	126	27	in	in	ADP
bjp-23981	126	28	table	table	NOUN
bjp-23981	126	29	iv	iv	NUM
bjp-23981	126	30	.	.	PUNCT
bjp-23981	127	1	the	the	DET
bjp-23981	127	2	result	result	NOUN
bjp-23981	127	3	of	of	ADP
bjp-23981	127	4	thrombolytic	thrombolytic	ADJ
bjp-23981	127	5	evaluation	evaluation	NOUN
bjp-23981	127	6	highlighted	highlight	VERB
bjp-23981	127	7	that	that	SCONJ
bjp-23981	127	8	compound	compound	VERB
bjp-23981	127	9	4j	4j	NOUN
bjp-23981	127	10	(	(	PUNCT
bjp-23981	127	11	pyridin-3	pyridin-3	NOUN
bjp-23981	127	12	-	-	PUNCT
bjp-23981	127	13	yl	yl	NOUN
bjp-23981	127	14	)	)	PUNCT
bjp-23981	127	15	,	,	PUNCT
bjp-23981	127	16	4d	4d	NUM
bjp-23981	127	17	(	(	PUNCT
bjp-23981	127	18	4	4	NUM
bjp-23981	127	19	-	-	PUNCT
bjp-23981	127	20	aminophenyl	aminophenyl	NOUN
bjp-23981	127	21	)	)	PUNCT
bjp-23981	127	22	,	,	PUNCT
bjp-23981	127	23	4	4	NUM
bjp-23981	127	24	g	g	NOUN
bjp-23981	127	25	(	(	PUNCT
bjp-23981	127	26	2hydroxyphenyl	2hydroxyphenyl	NUM
bjp-23981	127	27	)	)	PUNCT
bjp-23981	127	28	and	and	CCONJ
bjp-23981	127	29	4k	4k	NUM
bjp-23981	127	30	(	(	PUNCT
bjp-23981	127	31	mercapto	mercapto	PROPN
bjp-23981	127	32	)	)	PUNCT
bjp-23981	127	33	exhibited	exhibit	VERB
bjp-23981	127	34	potent	potent	ADJ
bjp-23981	127	35	clot	clot	NOUN
bjp-23981	127	36	lysis	lysis	NOUN
bjp-23981	127	37	efficacy	efficacy	NOUN
bjp-23981	127	38	than	than	ADP
bjp-23981	127	39	that	that	PRON
bjp-23981	127	40	of	of	ADP
bjp-23981	127	41	the	the	DET
bjp-23981	127	42	standard	standard	ADJ
bjp-23981	127	43	streptokinase	streptokinase	PROPN
bjp-23981	127	44	(	(	PUNCT
bjp-23981	127	45	46.57	46.57	NUM
bjp-23981	127	46	%	%	NOUN
bjp-23981	127	47	)	)	PUNCT
bjp-23981	127	48	at	at	ADP
bjp-23981	127	49	the	the	DET
bjp-23981	127	50	test	test	NOUN
bjp-23981	127	51	dose	dose	NOUN
bjp-23981	127	52	strength	strength	NOUN
bjp-23981	127	53	of	of	ADP
bjp-23981	127	54	25	25	NUM
bjp-23981	127	55	µm	µm	NOUN
bjp-23981	127	56	with	with	ADP
bjp-23981	127	57	an	an	DET
bjp-23981	127	58	percentage	percentage	NOUN
bjp-23981	127	59	clot	clot	NOUN
bjp-23981	127	60	lysis	lysis	NOUN
bjp-23981	127	61	of	of	ADP
bjp-23981	127	62	56.2	56.2	NUM
bjp-23981	127	63	,	,	PUNCT
bjp-23981	127	64	53.0	53.0	NUM
bjp-23981	127	65	,	,	PUNCT
bjp-23981	127	66	51.0	51.0	NUM
bjp-23981	127	67	and	and	CCONJ
bjp-23981	127	68	47.0	47.0	NUM
bjp-23981	127	69	%	%	NOUN
bjp-23981	127	70	,	,	PUNCT
bjp-23981	127	71	respectively	respectively	ADV
bjp-23981	127	72	in	in	ADP
bjp-23981	127	73	comparison	comparison	NOUN
bjp-23981	127	74	to	to	ADP
bjp-23981	127	75	the	the	DET
bjp-23981	127	76	other	other	ADJ
bjp-23981	127	77	set	set	NOUN
bjp-23981	127	78	of	of	ADP
bjp-23981	127	79	oxadiazole	oxadiazole	NOUN
bjp-23981	127	80	derivatives	derivative	NOUN
bjp-23981	127	81	.	.	PUNCT
bjp-23981	128	1	the	the	DET
bjp-23981	128	2	statistical	statistical	ADJ
bjp-23981	128	3	analysis	analysis	NOUN
bjp-23981	128	4	of	of	ADP
bjp-23981	128	5	the	the	DET
bjp-23981	128	6	cumulative	cumulative	ADJ
bjp-23981	128	7	clot	clot	NOUN
bjp-23981	128	8	lysis	lysis	NOUN
bjp-23981	128	9	data	datum	NOUN
bjp-23981	128	10	exhibited	exhibit	VERB
bjp-23981	128	11	by	by	ADP
bjp-23981	128	12	4a-4k	4a-4k	NOUN
bjp-23981	128	13	at	at	ADV
bjp-23981	128	14	all	all	DET
bjp-23981	128	15	three	three	NUM
bjp-23981	128	16	test	test	NOUN
bjp-23981	128	17	concentration	concentration	NOUN
bjp-23981	128	18	highlighted	highlight	VERB
bjp-23981	128	19	that	that	SCONJ
bjp-23981	128	20	compound	compound	NOUN
bjp-23981	128	21	4d-4k	4d-4k	NOUN
bjp-23981	128	22	exhibited	exhibit	VERB
bjp-23981	128	23	a	a	DET
bjp-23981	128	24	significance	significance	NOUN
bjp-23981	128	25	value	value	NOUN
bjp-23981	128	26	of	of	ADP
bjp-23981	128	27	p<0.001	p<0.001	NOUN
bjp-23981	128	28	with	with	ADP
bjp-23981	128	29	respect	respect	NOUN
bjp-23981	128	30	to	to	ADP
bjp-23981	128	31	table	table	NOUN
bjp-23981	128	32	iii	iii	NUM
bjp-23981	128	33	docking	docking	NOUN
bjp-23981	128	34	score	score	NOUN
bjp-23981	128	35	of	of	ADP
bjp-23981	128	36	1,3,4	1,3,4	NUM
bjp-23981	128	37	-	-	PUNCT
bjp-23981	128	38	oxadiazole	oxadiazole	NOUN
bjp-23981	128	39	derivatives	derivative	NOUN
bjp-23981	128	40	4a-4k	4a-4k	NUM
bjp-23981	128	41	towards	towards	ADP
bjp-23981	128	42	1nfy	1nfy	NUM
bjp-23981	128	43	sl	sl	NOUN
bjp-23981	128	44	.	.	PUNCT
bjp-23981	129	1	no	no	INTJ
bjp-23981	129	2	.	.	PUNCT
bjp-23981	130	1	compound	compound	NOUN
bjp-23981	130	2	total	total	NOUN
bjp-23981	130	3	scorea	scorea	NOUN
bjp-23981	130	4	crash	crash	NOUN
bjp-23981	130	5	scorea	scorea	VERB
bjp-23981	130	6	polar	polar	ADJ
bjp-23981	130	7	scorea	scorea	VERB
bjp-23981	130	8	1	1	NUM
bjp-23981	130	9	rpr132747	rpr132747	NOUN
bjp-23981	130	10	6.2	6.2	NUM
bjp-23981	130	11	-2.2	-2.2	NUM
bjp-23981	130	12	0.8	0.8	NUM
bjp-23981	130	13	2	2	NUM
bjp-23981	130	14	4a	4a	NOUN
bjp-23981	130	15	7.2	7.2	NUM
bjp-23981	130	16	-0.7	-0.7	PROPN
bjp-23981	130	17	1.7	1.7	NUM
bjp-23981	130	18	3	3	NUM
bjp-23981	130	19	4b	4b	PROPN
bjp-23981	130	20	7.4	7.4	NUM
bjp-23981	130	21	-0.5	-0.5	NUM
bjp-23981	130	22	4.1	4.1	NUM
bjp-23981	130	23	4	4	NUM
bjp-23981	130	24	4c	4c	NOUN
bjp-23981	130	25	8.4	8.4	NUM
bjp-23981	130	26	-0.4	-0.4	NUM
bjp-23981	130	27	3.6	3.6	NUM
bjp-23981	130	28	5	5	NUM
bjp-23981	130	29	4d	4d	NUM
bjp-23981	130	30	8.8	8.8	NUM
bjp-23981	130	31	-0.9	-0.9	NOUN
bjp-23981	130	32	4.2	4.2	NUM
bjp-23981	130	33	6	6	NUM
bjp-23981	130	34	4e	4e	NOUN
bjp-23981	130	35	7.8	7.8	NUM
bjp-23981	130	36	-1.2	-1.2	NUM
bjp-23981	130	37	1.3	1.3	NUM
bjp-23981	130	38	7	7	NUM
bjp-23981	130	39	4f	4f	NUM
bjp-23981	130	40	7.5	7.5	NUM
bjp-23981	130	41	-0.7	-0.7	NOUN
bjp-23981	130	42	3.7	3.7	NUM
bjp-23981	130	43	8	8	NUM
bjp-23981	130	44	4	4	NUM
bjp-23981	130	45	g	g	ADP
bjp-23981	130	46	8.2	8.2	NUM
bjp-23981	130	47	-1.0	-1.0	PROPN
bjp-23981	130	48	1.6	1.6	NUM
bjp-23981	130	49	9	9	NUM
bjp-23981	130	50	4h	4h	NUM
bjp-23981	130	51	7.7	7.7	NUM
bjp-23981	130	52	-0.9	-0.9	NOUN
bjp-23981	130	53	1.5	1.5	NUM
bjp-23981	130	54	10	10	NUM
bjp-23981	130	55	4i	4i	NUM
bjp-23981	130	56	6.7	6.7	NUM
bjp-23981	130	57	-0.4	-0.4	NUM
bjp-23981	130	58	3.6	3.6	NUM
bjp-23981	130	59	11	11	NUM
bjp-23981	130	60	4j	4j	NOUN
bjp-23981	130	61	7.4	7.4	NUM
bjp-23981	130	62	-0.7	-0.7	NOUN
bjp-23981	130	63	3.4	3.4	NUM
bjp-23981	130	64	12	12	NUM
bjp-23981	130	65	4k	4k	NUM
bjp-23981	130	66	6.6	6.6	NUM
bjp-23981	130	67	-0.3	-0.3	NUM
bjp-23981	130	68	3.6	3.6	NUM
bjp-23981	130	69	adata	adata	NOUN
bjp-23981	130	70	expressed	express	VERB
bjp-23981	130	71	in	in	ADP
bjp-23981	130	72	kcal	kcal	PROPN
bjp-23981	130	73	m-1	m-1	PROPN
bjp-23981	130	74	as	as	SCONJ
bjp-23981	130	75	obtained	obtain	VERB
bjp-23981	130	76	from	from	ADP
bjp-23981	130	77	the	the	DET
bjp-23981	130	78	docking	docking	NOUN
bjp-23981	130	79	utility	utility	NOUN
bjp-23981	130	80	of	of	ADP
bjp-23981	130	81	sybyl	sybyl	NOUN
bjp-23981	130	82	2.1	2.1	NUM
bjp-23981	130	83	software	software	NOUN
bjp-23981	130	84	72	72	NUM
bjp-23981	130	85	bangladesh	bangladesh	NOUN
bjp-23981	130	86	j	j	PROPN
bjp-23981	130	87	pharmacol	pharmacol	PROPN
bjp-23981	130	88	2016	2016	NUM
bjp-23981	130	89	;	;	PUNCT
bjp-23981	130	90	11	11	NUM
bjp-23981	130	91	:	:	SYM
bjp-23981	130	92	67	67	NUM
bjp-23981	130	93	-	-	SYM
bjp-23981	130	94	74	74	NUM
bjp-23981	130	95	control	control	NOUN
bjp-23981	130	96	.	.	PUNCT
bjp-23981	131	1	compound	compound	NOUN
bjp-23981	131	2	4b	4b	PROPN
bjp-23981	131	3	and	and	CCONJ
bjp-23981	131	4	4c	4c	NOUN
bjp-23981	131	5	exhibited	exhibit	VERB
bjp-23981	131	6	a	a	DET
bjp-23981	131	7	significance	significance	NOUN
bjp-23981	131	8	value	value	NOUN
bjp-23981	131	9	of	of	ADP
bjp-23981	131	10	p<0.05	p<0.05	NOUN
bjp-23981	131	11	highlighting	highlight	VERB
bjp-23981	131	12	the	the	DET
bjp-23981	131	13	confidence	confidence	NOUN
bjp-23981	131	14	interval	interval	NOUN
bjp-23981	131	15	of	of	ADP
bjp-23981	131	16	only	only	ADV
bjp-23981	131	17	95.0	95.0	NUM
bjp-23981	131	18	%	%	NOUN
bjp-23981	131	19	with	with	ADP
bjp-23981	131	20	respect	respect	NOUN
bjp-23981	131	21	to	to	ADP
bjp-23981	131	22	control	control	NOUN
bjp-23981	131	23	(	(	PUNCT
bjp-23981	131	24	figure	figure	NOUN
bjp-23981	131	25	4	4	NUM
bjp-23981	131	26	)	)	PUNCT
bjp-23981	131	27	.	.	PUNCT
bjp-23981	132	1	discussion	discussion	NOUN
bjp-23981	132	2	the	the	DET
bjp-23981	132	3	docking	docking	NOUN
bjp-23981	132	4	studies	study	NOUN
bjp-23981	132	5	towards	towards	ADP
bjp-23981	132	6	thrombolytic	thrombolytic	ADJ
bjp-23981	132	7	efficacy	efficacy	NOUN
bjp-23981	132	8	indicated	indicate	VERB
bjp-23981	132	9	all	all	DET
bjp-23981	132	10	the	the	DET
bjp-23981	132	11	eleven	eleven	NUM
bjp-23981	132	12	1,3,4	1,3,4	NUM
bjp-23981	132	13	-	-	PUNCT
bjp-23981	132	14	oxadiazoles	oxadiazole	NOUN
bjp-23981	132	15	have	have	VERB
bjp-23981	132	16	better	well	ADJ
bjp-23981	132	17	affinity	affinity	NOUN
bjp-23981	132	18	to	to	PART
bjp-23981	132	19	inhibit	inhibit	VERB
bjp-23981	132	20	fxa	fxa	NOUN
bjp-23981	132	21	(	(	PUNCT
bjp-23981	132	22	1nfy	1nfy	NOUN
bjp-23981	132	23	)	)	PUNCT
bjp-23981	132	24	enzyme	enzyme	NOUN
bjp-23981	132	25	with	with	ADP
bjp-23981	132	26	a	a	DET
bjp-23981	132	27	overall	overall	ADJ
bjp-23981	132	28	higher	high	ADJ
bjp-23981	132	29	docking	docking	NOUN
bjp-23981	132	30	score	score	NOUN
bjp-23981	132	31	in	in	ADP
bjp-23981	132	32	comparison	comparison	NOUN
bjp-23981	132	33	to	to	ADP
bjp-23981	132	34	the	the	DET
bjp-23981	132	35	control	control	PROPN
bjp-23981	132	36	ligand	ligand	PROPN
bjp-23981	132	37	rpr132747	rpr132747	NOUN
bjp-23981	132	38	and	and	CCONJ
bjp-23981	132	39	all	all	DET
bjp-23981	132	40	the	the	DET
bjp-23981	132	41	designed	design	VERB
bjp-23981	132	42	1,3,4	1,3,4	NUM
bjp-23981	132	43	-	-	PUNCT
bjp-23981	132	44	oxadiazoles	oxadiazole	NOUN
bjp-23981	132	45	exhibited	exhibit	VERB
bjp-23981	132	46	considerably	considerably	ADV
bjp-23981	132	47	lower	low	ADJ
bjp-23981	132	48	crash	crash	NOUN
bjp-23981	132	49	score	score	NOUN
bjp-23981	132	50	than	than	ADP
bjp-23981	132	51	that	that	PRON
bjp-23981	132	52	of	of	ADP
bjp-23981	132	53	the	the	DET
bjp-23981	132	54	control	control	PROPN
bjp-23981	132	55	ligand	ligand	PROPN
bjp-23981	132	56	rpr132747	rpr132747	NOUN
bjp-23981	132	57	,	,	PUNCT
bjp-23981	132	58	highlighting	highlight	VERB
bjp-23981	132	59	the	the	DET
bjp-23981	132	60	potential	potential	NOUN
bjp-23981	132	61	of	of	ADP
bjp-23981	132	62	the	the	DET
bjp-23981	132	63	designed	design	VERB
bjp-23981	132	64	1,3,4	1,3,4	NUM
bjp-23981	132	65	-	-	NOUN
bjp-23981	132	66	oxadiazoles	oxadiazole	NOUN
bjp-23981	132	67	as	as	ADP
bjp-23981	132	68	antithrombotic	antithrombotic	ADJ
bjp-23981	132	69	agents	agent	NOUN
bjp-23981	132	70	.	.	PUNCT
bjp-23981	133	1	the	the	PRON
bjp-23981	133	2	in	in	ADP
bjp-23981	133	3	silico	silico	NOUN
bjp-23981	133	4	adme	adme	VERB
bjp-23981	133	5	studies	study	NOUN
bjp-23981	133	6	highlighted	highlight	VERB
bjp-23981	133	7	that	that	SCONJ
bjp-23981	133	8	the	the	DET
bjp-23981	133	9	designed	design	VERB
bjp-23981	133	10	1,3,4	1,3,4	NUM
bjp-23981	133	11	-	-	PUNCT
bjp-23981	133	12	oxadiazoles	oxadiazole	NOUN
bjp-23981	133	13	have	have	VERB
bjp-23981	133	14	potential	potential	ADJ
bjp-23981	133	15	as	as	ADP
bjp-23981	133	16	drug	drug	NOUN
bjp-23981	133	17	candidate	candidate	NOUN
bjp-23981	133	18	with	with	ADP
bjp-23981	133	19	appropriate	appropriate	ADJ
bjp-23981	133	20	values	value	NOUN
bjp-23981	133	21	towards	towards	ADP
bjp-23981	133	22	lipinski	lipinski	PROPN
bjp-23981	133	23	parameters	parameter	NOUN
bjp-23981	133	24	for	for	ADP
bjp-23981	133	25	biological	biological	ADJ
bjp-23981	133	26	efficacy	efficacy	NOUN
bjp-23981	133	27	and	and	CCONJ
bjp-23981	133	28	also	also	ADV
bjp-23981	133	29	with	with	ADP
bjp-23981	133	30	optimal	optimal	ADJ
bjp-23981	133	31	values	value	NOUN
bjp-23981	133	32	required	require	VERB
bjp-23981	133	33	for	for	ADP
bjp-23981	133	34	pharmacokinetic	pharmacokinetic	ADJ
bjp-23981	133	35	importance	importance	NOUN
bjp-23981	133	36	.	.	PUNCT
bjp-23981	134	1	the	the	DET
bjp-23981	134	2	results	result	NOUN
bjp-23981	134	3	of	of	ADP
bjp-23981	134	4	the	the	DET
bjp-23981	134	5	in	in	X
bjp-23981	134	6	vitro	vitro	X
bjp-23981	134	7	thrombolytic	thrombolytic	ADJ
bjp-23981	134	8	activity	activity	NOUN
bjp-23981	134	9	were	be	AUX
bjp-23981	134	10	encouraging	encouraging	ADJ
bjp-23981	134	11	as	as	SCONJ
bjp-23981	134	12	the	the	DET
bjp-23981	134	13	tested	test	VERB
bjp-23981	134	14	compounds	compound	NOUN
bjp-23981	134	15	exhibited	exhibit	VERB
bjp-23981	134	16	substantial	substantial	ADJ
bjp-23981	134	17	clot	clot	NOUN
bjp-23981	134	18	lysis	lysis	NOUN
bjp-23981	134	19	activity	activity	NOUN
bjp-23981	134	20	.	.	PUNCT
bjp-23981	135	1	all	all	DET
bjp-23981	135	2	the	the	DET
bjp-23981	135	3	eleven	eleven	NUM
bjp-23981	135	4	tested	test	VERB
bjp-23981	135	5	1,3,4oxadiazole	1,3,4oxadiazole	NUM
bjp-23981	135	6	derivative	derivative	NOUN
bjp-23981	135	7	exhibited	exhibit	VERB
bjp-23981	135	8	moderate	moderate	ADJ
bjp-23981	135	9	to	to	PART
bjp-23981	135	10	potent	potent	VERB
bjp-23981	135	11	clot	clot	NOUN
bjp-23981	135	12	lysis	lysis	NOUN
bjp-23981	135	13	,	,	PUNCT
bjp-23981	135	14	with	with	ADP
bjp-23981	135	15	mean	mean	ADJ
bjp-23981	135	16	percentage	percentage	NOUN
bjp-23981	135	17	clot	clot	NOUN
bjp-23981	135	18	lysis	lysis	NOUN
bjp-23981	135	19	value	value	NOUN
bjp-23981	135	20	ranging	range	VERB
bjp-23981	135	21	from	from	ADP
bjp-23981	135	22	12.0	12.0	NUM
bjp-23981	135	23	to	to	PART
bjp-23981	135	24	56.2	56.2	NUM
bjp-23981	135	25	%	%	NOUN
bjp-23981	135	26	in	in	ADP
bjp-23981	135	27	comparison	comparison	NOUN
bjp-23981	135	28	to	to	ADP
bjp-23981	135	29	46.6	46.6	NUM
bjp-23981	135	30	%	%	NOUN
bjp-23981	135	31	clot	clot	NOUN
bjp-23981	135	32	lysis	lysis	NOUN
bjp-23981	135	33	exhibited	exhibit	VERB
bjp-23981	135	34	by	by	ADP
bjp-23981	135	35	the	the	DET
bjp-23981	135	36	reference	reference	NOUN
bjp-23981	135	37	standard	standard	PROPN
bjp-23981	135	38	streptokinase	streptokinase	PROPN
bjp-23981	135	39	(	(	PUNCT
bjp-23981	135	40	30,000	30,000	NUM
bjp-23981	135	41	iu	iu	NOUN
bjp-23981	135	42	)	)	PUNCT
bjp-23981	135	43	.	.	PUNCT
bjp-23981	136	1	the	the	DET
bjp-23981	136	2	compounds	compound	NOUN
bjp-23981	136	3	4a-4k	4a-4k	X
bjp-23981	136	4	at	at	ADP
bjp-23981	136	5	the	the	DET
bjp-23981	136	6	testing	testing	NOUN
bjp-23981	136	7	strength	strength	NOUN
bjp-23981	136	8	of	of	ADP
bjp-23981	136	9	6.25	6.25	NUM
bjp-23981	136	10	µm	µm	NUM
bjp-23981	136	11	exhibited	exhibit	VERB
bjp-23981	136	12	a	a	DET
bjp-23981	136	13	mean	mean	ADJ
bjp-23981	136	14	clot	clot	NOUN
bjp-23981	136	15	lysis	lysis	NOUN
bjp-23981	136	16	ranging	range	VERB
bjp-23981	136	17	from	from	ADP
bjp-23981	136	18	12.0	12.0	NUM
bjp-23981	136	19	to	to	ADP
bjp-23981	136	20	43.7	43.7	NUM
bjp-23981	136	21	%	%	NOUN
bjp-23981	136	22	.	.	PUNCT
bjp-23981	137	1	compound	compound	NOUN
bjp-23981	137	2	4d	4d	NOUN
bjp-23981	137	3	(	(	PUNCT
bjp-23981	137	4	4	4	NUM
bjp-23981	137	5	-	-	PUNCT
bjp-23981	137	6	aminophenyl	aminophenyl	NOUN
bjp-23981	137	7	)	)	PUNCT
bjp-23981	137	8	exhibited	exhibit	VERB
bjp-23981	137	9	the	the	DET
bjp-23981	137	10	highest	high	ADJ
bjp-23981	137	11	thrombolytic	thrombolytic	ADJ
bjp-23981	137	12	activity	activity	NOUN
bjp-23981	137	13	among	among	ADP
bjp-23981	137	14	the	the	DET
bjp-23981	137	15	series	series	NOUN
bjp-23981	137	16	with	with	ADP
bjp-23981	137	17	mean	mean	NOUN
bjp-23981	137	18	clot	clot	NOUN
bjp-23981	137	19	lysis	lysis	NOUN
bjp-23981	137	20	value	value	NOUN
bjp-23981	137	21	of	of	ADP
bjp-23981	137	22	43.7	43.7	NUM
bjp-23981	137	23	%	%	NOUN
bjp-23981	137	24	and	and	CCONJ
bjp-23981	137	25	compound	compound	NOUN
bjp-23981	137	26	4a	4a	NOUN
bjp-23981	137	27	(	(	PUNCT
bjp-23981	137	28	phenyl	phenyl	NOUN
bjp-23981	137	29	)	)	PUNCT
bjp-23981	137	30	exhibited	exhibit	VERB
bjp-23981	137	31	the	the	DET
bjp-23981	137	32	least	least	ADJ
bjp-23981	137	33	activity	activity	NOUN
bjp-23981	137	34	with	with	ADP
bjp-23981	137	35	mean	mean	ADJ
bjp-23981	137	36	clot	clot	NOUN
bjp-23981	137	37	lysis	lysis	NOUN
bjp-23981	137	38	value	value	NOUN
bjp-23981	137	39	of	of	ADP
bjp-23981	137	40	12.0	12.0	NUM
bjp-23981	137	41	%	%	NOUN
bjp-23981	137	42	.	.	PUNCT
bjp-23981	138	1	the	the	DET
bjp-23981	138	2	statistical	statistical	ADJ
bjp-23981	138	3	analysis	analysis	NOUN
bjp-23981	138	4	of	of	ADP
bjp-23981	138	5	the	the	DET
bjp-23981	138	6	compounds	compound	NOUN
bjp-23981	138	7	thrombolytic	thrombolytic	ADJ
bjp-23981	138	8	activity	activity	NOUN
bjp-23981	138	9	highlighted	highlight	VERB
bjp-23981	138	10	that	that	SCONJ
bjp-23981	138	11	the	the	DET
bjp-23981	138	12	compounds	compound	NOUN
bjp-23981	138	13	4a-4k	4a-4k	PRON
bjp-23981	138	14	exhibited	exhibit	VERB
bjp-23981	138	15	a	a	DET
bjp-23981	138	16	significance	significance	NOUN
bjp-23981	138	17	value	value	NOUN
bjp-23981	138	18	of	of	ADP
bjp-23981	138	19	p<0.001	p<0.001	NOUN
bjp-23981	138	20	highlighting	highlight	VERB
bjp-23981	138	21	p	p	PROPN
bjp-23981	138	22	er	er	INTJ
bjp-23981	138	23	ce	ce	PROPN
bjp-23981	138	24	nt	not	PART
bjp-23981	138	25	ag	ag	PROPN
bjp-23981	138	26	e	e	PROPN
bjp-23981	138	27	cl	cl	NOUN
bjp-23981	138	28	ot	ot	NOUN
bjp-23981	138	29	ly	ly	ADP
bjp-23981	138	30	si	si	PROPN
bjp-23981	138	31	s	s	PART
bjp-23981	138	32	60	60	NUM
bjp-23981	138	33	40	40	NUM
bjp-23981	138	34	20	20	NUM
bjp-23981	138	35	0	0	NUM
bjp-23981	138	36	cont	cont	NOUN
bjp-23981	138	37	.	.	PUNCT
bjp-23981	139	1	4a	4a	NOUN
bjp-23981	139	2	4b	4b	PROPN
bjp-23981	139	3	4c	4c	PROPN
bjp-23981	139	4	4d	4d	NUM
bjp-23981	139	5	4e	4e	NOUN
bjp-23981	139	6	4f	4f	NUM
bjp-23981	139	7	4	4	NUM
bjp-23981	139	8	g	g	NOUN
bjp-23981	139	9	4h	4h	NUM
bjp-23981	139	10	4i	4i	NOUN
bjp-23981	139	11	4j	4j	NOUN
bjp-23981	139	12	4k	4k	PRON
bjp-23981	139	13	figure	figure	VERB
bjp-23981	139	14	4	4	NUM
bjp-23981	139	15	:	:	PUNCT
bjp-23981	139	16	mean	mean	VERB
bjp-23981	139	17	percentage	percentage	NOUN
bjp-23981	139	18	cot	cot	NOUN
bjp-23981	139	19	lysis	lysis	NOUN
bjp-23981	139	20	exhibited	exhibit	VERB
bjp-23981	139	21	by	by	ADP
bjp-23981	139	22	4a-4k	4a-4k	DET
bjp-23981	139	23	table	table	NOUN
bjp-23981	139	24	iv	iv	NUM
bjp-23981	139	25	in	in	ADP
bjp-23981	139	26	vitro	vitro	X
bjp-23981	139	27	thrombolytic	thrombolytic	ADJ
bjp-23981	139	28	activity	activity	NOUN
bjp-23981	139	29	data	datum	NOUN
bjp-23981	139	30	of	of	ADP
bjp-23981	139	31	the	the	DET
bjp-23981	139	32	compounds	compound	NOUN
bjp-23981	139	33	4a-4k	4a-4k	INTJ
bjp-23981	140	1	sl	sl	INTJ
bjp-23981	140	2	no	no	INTJ
bjp-23981	140	3	.	.	PUNCT
bjp-23981	141	1	compoundsa	compoundsa	NOUN
bjp-23981	141	2	mean	mean	VERB
bjp-23981	141	3	percentage	percentage	NOUN
bjp-23981	141	4	clot	clot	NOUN
bjp-23981	141	5	lysis	lysis	NOUN
bjp-23981	141	6	±	±	NOUN
bjp-23981	141	7	sembc	sembc	NOUN
bjp-23981	141	8	mean	mean	VERB
bjp-23981	142	1	ec50	ec50	PROPN
bjp-23981	142	2	value	value	NOUN
bjp-23981	142	3	±	±	NUM
bjp-23981	142	4	sem	sem	NOUN
bjp-23981	142	5	(	(	PUNCT
bjp-23981	142	6	µm)c	µm)c	PROPN
bjp-23981	142	7	6.25	6.25	NUM
bjp-23981	142	8	µm	µm	ADP
bjp-23981	142	9	12.5	12.5	NUM
bjp-23981	142	10	µm	µm	ADP
bjp-23981	142	11	25	25	NUM
bjp-23981	142	12	µm	µm	SYM
bjp-23981	142	13	1	1	NUM
bjp-23981	142	14	control	control	NOUN
bjp-23981	142	15	2.0	2.0	NUM
bjp-23981	142	16	±	±	NUM
bjp-23981	142	17	0.2	0.2	NUM
bjp-23981	142	18	2.6	2.6	NUM
bjp-23981	142	19	±	±	NUM
bjp-23981	142	20	0.7	0.7	NUM
bjp-23981	142	21	2.6	2.6	NUM
bjp-23981	142	22	±	±	NUM
bjp-23981	142	23	0.3	0.3	NUM
bjp-23981	142	24	2	2	NUM
bjp-23981	142	25	4a	4a	NOUN
bjp-23981	142	26	12.0	12.0	NUM
bjp-23981	142	27	±	±	NUM
bjp-23981	142	28	0.3	0.3	NUM
bjp-23981	142	29	*	*	PUNCT
bjp-23981	142	30	*	*	PUNCT
bjp-23981	142	31	*	*	PUNCT
bjp-23981	142	32	16.0	16.0	NUM
bjp-23981	142	33	±	±	NUM
bjp-23981	142	34	0.6	0.6	NUM
bjp-23981	142	35	*	*	PUNCT
bjp-23981	142	36	*	*	PUNCT
bjp-23981	142	37	*	*	PUNCT
bjp-23981	142	38	22.5	22.5	NUM
bjp-23981	142	39	±	±	NUM
bjp-23981	142	40	0.4	0.4	NUM
bjp-23981	142	41	*	*	PUNCT
bjp-23981	142	42	*	*	PUNCT
bjp-23981	142	43	*	*	PUNCT
bjp-23981	142	44	74.8	74.8	NUM
bjp-23981	142	45	±	±	NUM
bjp-23981	142	46	1.1	1.1	NUM
bjp-23981	142	47	3	3	NUM
bjp-23981	142	48	4b	4b	X
bjp-23981	142	49	*	*	PROPN
bjp-23981	142	50	14.4	14.4	NUM
bjp-23981	142	51	±	±	NUM
bjp-23981	142	52	0.3	0.3	NUM
bjp-23981	142	53	*	*	PUNCT
bjp-23981	142	54	*	*	PUNCT
bjp-23981	142	55	*	*	PUNCT
bjp-23981	142	56	20.5	20.5	NUM
bjp-23981	142	57	±	±	NUM
bjp-23981	142	58	0.8	0.8	NUM
bjp-23981	142	59	*	*	PUNCT
bjp-23981	142	60	*	*	PUNCT
bjp-23981	142	61	*	*	PUNCT
bjp-23981	142	62	30.9	30.9	NUM
bjp-23981	142	63	±	±	NUM
bjp-23981	142	64	0.1	0.1	NUM
bjp-23981	142	65	*	*	PUNCT
bjp-23981	142	66	*	*	PUNCT
bjp-23981	142	67	*	*	PUNCT
bjp-23981	142	68	46.7	46.7	NUM
bjp-23981	142	69	±	±	NUM
bjp-23981	142	70	0.2	0.2	NUM
bjp-23981	142	71	4	4	NUM
bjp-23981	142	72	4c	4c	NOUN
bjp-23981	142	73	*	*	PUNCT
bjp-23981	142	74	20.8	20.8	NUM
bjp-23981	142	75	±	±	NUM
bjp-23981	142	76	1.5	1.5	NUM
bjp-23981	142	77	*	*	PUNCT
bjp-23981	142	78	*	*	PUNCT
bjp-23981	142	79	*	*	PUNCT
bjp-23981	142	80	24.1	24.1	NUM
bjp-23981	142	81	±	±	NUM
bjp-23981	142	82	0.2	0.2	NUM
bjp-23981	142	83	*	*	PUNCT
bjp-23981	142	84	*	*	PUNCT
bjp-23981	142	85	*	*	PUNCT
bjp-23981	142	86	28.9	28.9	NUM
bjp-23981	142	87	±	±	NUM
bjp-23981	142	88	0.8	0.8	NUM
bjp-23981	142	89	*	*	PUNCT
bjp-23981	142	90	*	*	PUNCT
bjp-23981	142	91	*	*	PUNCT
bjp-23981	142	92	74.2	74.2	NUM
bjp-23981	142	93	±	±	NUM
bjp-23981	142	94	1.4	1.4	NUM
bjp-23981	142	95	5	5	NUM
bjp-23981	142	96	4d	4d	NUM
bjp-23981	142	97	*	*	PUNCT
bjp-23981	142	98	*	*	PUNCT
bjp-23981	142	99	*	*	PUNCT
bjp-23981	142	100	43.7	43.7	NUM
bjp-23981	142	101	±	±	NUM
bjp-23981	142	102	0.7	0.7	NUM
bjp-23981	142	103	*	*	PUNCT
bjp-23981	142	104	*	*	PUNCT
bjp-23981	142	105	*	*	PUNCT
bjp-23981	142	106	47.0	47.0	NUM
bjp-23981	142	107	±	±	NUM
bjp-23981	142	108	0.3	0.3	NUM
bjp-23981	142	109	*	*	PUNCT
bjp-23981	142	110	*	*	PUNCT
bjp-23981	142	111	*	*	PUNCT
bjp-23981	142	112	53.0	53.0	NUM
bjp-23981	142	113	±	±	NUM
bjp-23981	142	114	0.3	0.3	NUM
bjp-23981	142	115	*	*	PUNCT
bjp-23981	142	116	*	*	PUNCT
bjp-23981	142	117	*	*	PUNCT
bjp-23981	142	118	18.8	18.8	NUM
bjp-23981	142	119	±	±	NUM
bjp-23981	142	120	0.3	0.3	NUM
bjp-23981	142	121	6	6	NUM
bjp-23981	142	122	4e	4e	NOUN
bjp-23981	142	123	*	*	PUNCT
bjp-23981	142	124	*	*	PUNCT
bjp-23981	142	125	*	*	PUNCT
bjp-23981	142	126	21.7	21.7	NUM
bjp-23981	142	127	±	±	NUM
bjp-23981	142	128	0.8	0.8	NUM
bjp-23981	142	129	*	*	PUNCT
bjp-23981	142	130	*	*	PUNCT
bjp-23981	142	131	*	*	PUNCT
bjp-23981	142	132	30.9	30.9	NUM
bjp-23981	142	133	±	±	NUM
bjp-23981	142	134	0.8	0.8	NUM
bjp-23981	142	135	*	*	PUNCT
bjp-23981	142	136	*	*	PUNCT
bjp-23981	142	137	*	*	PUNCT
bjp-23981	142	138	45.0	45.0	NUM
bjp-23981	142	139	±	±	NUM
bjp-23981	142	140	0.6	0.6	NUM
bjp-23981	142	141	*	*	PUNCT
bjp-23981	142	142	*	*	PUNCT
bjp-23981	142	143	*	*	PUNCT
bjp-23981	142	144	28.9	28.9	NUM
bjp-23981	142	145	±	±	NUM
bjp-23981	142	146	0.3	0.3	NUM
bjp-23981	142	147	7	7	NUM
bjp-23981	142	148	4f	4f	NUM
bjp-23981	142	149	*	*	PUNCT
bjp-23981	142	150	*	*	PUNCT
bjp-23981	142	151	*	*	PUNCT
bjp-23981	142	152	28.9	28.9	NUM
bjp-23981	142	153	±	±	NUM
bjp-23981	142	154	0.5	0.5	NUM
bjp-23981	142	155	*	*	PUNCT
bjp-23981	142	156	*	*	PUNCT
bjp-23981	142	157	*	*	PUNCT
bjp-23981	142	158	32.6	32.6	NUM
bjp-23981	142	159	±	±	NUM
bjp-23981	142	160	0.4	0.4	NUM
bjp-23981	142	161	*	*	PUNCT
bjp-23981	142	162	*	*	PUNCT
bjp-23981	142	163	*	*	PUNCT
bjp-23981	142	164	40.6	40.6	NUM
bjp-23981	142	165	±	±	NUM
bjp-23981	142	166	0.7	0.7	NUM
bjp-23981	142	167	*	*	PUNCT
bjp-23981	142	168	*	*	PUNCT
bjp-23981	142	169	*	*	PUNCT
bjp-23981	142	170	40.3	40.3	NUM
bjp-23981	142	171	±	±	NUM
bjp-23981	142	172	1.7	1.7	NUM
bjp-23981	142	173	8	8	NUM
bjp-23981	142	174	4	4	NUM
bjp-23981	142	175	g	g	NOUN
bjp-23981	142	176	*	*	NOUN
bjp-23981	142	177	*	*	PUNCT
bjp-23981	142	178	*	*	PUNCT
bjp-23981	142	179	33.0	33.0	NUM
bjp-23981	142	180	±	±	NUM
bjp-23981	142	181	0.8	0.8	NUM
bjp-23981	142	182	*	*	PUNCT
bjp-23981	142	183	*	*	PUNCT
bjp-23981	142	184	*	*	PUNCT
bjp-23981	142	185	40.1	40.1	NUM
bjp-23981	142	186	±	±	NUM
bjp-23981	142	187	0.9	0.9	NUM
bjp-23981	142	188	*	*	PUNCT
bjp-23981	142	189	*	*	PUNCT
bjp-23981	142	190	*	*	PUNCT
bjp-23981	142	191	51.0	51.0	NUM
bjp-23981	142	192	±	±	NUM
bjp-23981	142	193	0.2	0.2	NUM
bjp-23981	142	194	*	*	PUNCT
bjp-23981	142	195	*	*	PUNCT
bjp-23981	142	196	*	*	PUNCT
bjp-23981	142	197	23.7	23.7	NUM
bjp-23981	142	198	±	±	NUM
bjp-23981	142	199	0.2	0.2	NUM
bjp-23981	142	200	9	9	NUM
bjp-23981	142	201	4h	4h	NUM
bjp-23981	142	202	*	*	PUNCT
bjp-23981	142	203	*	*	PUNCT
bjp-23981	142	204	*	*	PUNCT
bjp-23981	142	205	28.1	28.1	NUM
bjp-23981	142	206	±	±	NUM
bjp-23981	142	207	0.4	0.4	NUM
bjp-23981	142	208	*	*	PUNCT
bjp-23981	142	209	*	*	PUNCT
bjp-23981	142	210	*	*	PUNCT
bjp-23981	142	211	32.6	32.6	NUM
bjp-23981	142	212	±	±	NUM
bjp-23981	142	213	0.4	0.4	NUM
bjp-23981	142	214	*	*	PUNCT
bjp-23981	142	215	*	*	PUNCT
bjp-23981	142	216	*	*	PUNCT
bjp-23981	142	217	40.5	40.5	NUM
bjp-23981	142	218	±	±	NUM
bjp-23981	142	219	0.5	0.5	NUM
bjp-23981	142	220	*	*	PUNCT
bjp-23981	142	221	*	*	PUNCT
bjp-23981	142	222	*	*	PUNCT
bjp-23981	142	223	39.4	39.4	NUM
bjp-23981	142	224	±	±	NUM
bjp-23981	142	225	1.2	1.2	NUM
bjp-23981	142	226	10	10	NUM
bjp-23981	142	227	4i	4i	NOUN
bjp-23981	142	228	*	*	PUNCT
bjp-23981	142	229	*	*	PUNCT
bjp-23981	142	230	*	*	PUNCT
bjp-23981	142	231	20.9	20.9	NUM
bjp-23981	142	232	±	±	NUM
bjp-23981	142	233	0.3	0.3	NUM
bjp-23981	142	234	*	*	PUNCT
bjp-23981	142	235	*	*	PUNCT
bjp-23981	142	236	*	*	PUNCT
bjp-23981	142	237	34.6	34.6	NUM
bjp-23981	142	238	±	±	NUM
bjp-23981	142	239	0.7	0.7	NUM
bjp-23981	142	240	*	*	PUNCT
bjp-23981	142	241	*	*	PUNCT
bjp-23981	142	242	*	*	PUNCT
bjp-23981	142	243	39.3	39.3	NUM
bjp-23981	142	244	±	±	NUM
bjp-23981	142	245	1.0	1.0	NUM
bjp-23981	142	246	*	*	PUNCT
bjp-23981	142	247	*	*	PUNCT
bjp-23981	142	248	*	*	PUNCT
bjp-23981	142	249	35.4	35.4	NUM
bjp-23981	142	250	±	±	NUM
bjp-23981	142	251	1.7	1.7	NUM
bjp-23981	142	252	11	11	NUM
bjp-23981	142	253	4j	4j	NOUN
bjp-23981	142	254	*	*	PUNCT
bjp-23981	142	255	*	*	PUNCT
bjp-23981	142	256	*	*	X
bjp-23981	142	257	40.9	40.9	NUM
bjp-23981	142	258	±	±	NOUN
bjp-23981	142	259	0.6	0.6	NUM
bjp-23981	142	260	*	*	PUNCT
bjp-23981	142	261	*	*	PUNCT
bjp-23981	142	262	*	*	PUNCT
bjp-23981	142	263	49.0	49.0	NUM
bjp-23981	142	264	±	±	NUM
bjp-23981	142	265	0.2	0.2	NUM
bjp-23981	142	266	*	*	PUNCT
bjp-23981	142	267	*	*	PUNCT
bjp-23981	142	268	*	*	PUNCT
bjp-23981	142	269	56.2	56.2	NUM
bjp-23981	142	270	±	±	NUM
bjp-23981	142	271	0.6	0.6	NUM
bjp-23981	142	272	*	*	PUNCT
bjp-23981	142	273	*	*	PUNCT
bjp-23981	142	274	*	*	PUNCT
bjp-23981	142	275	16.2	16.2	NUM
bjp-23981	142	276	±	±	NUM
bjp-23981	142	277	0.3	0.3	NUM
bjp-23981	142	278	12	12	NUM
bjp-23981	142	279	4k	4k	NOUN
bjp-23981	142	280	*	*	PUNCT
bjp-23981	142	281	*	*	PUNCT
bjp-23981	142	282	*	*	PUNCT
bjp-23981	142	283	25.2	25.2	NUM
bjp-23981	142	284	±	±	NUM
bjp-23981	142	285	1.0	1.0	NUM
bjp-23981	142	286	*	*	PUNCT
bjp-23981	142	287	*	*	PUNCT
bjp-23981	142	288	*	*	PUNCT
bjp-23981	142	289	34.5	34.5	NUM
bjp-23981	142	290	±	±	NUM
bjp-23981	142	291	0.7	0.7	NUM
bjp-23981	142	292	*	*	PUNCT
bjp-23981	142	293	*	*	PUNCT
bjp-23981	142	294	*	*	PUNCT
bjp-23981	142	295	47.0	47.0	NUM
bjp-23981	142	296	±	±	NUM
bjp-23981	142	297	0.5	0.5	NUM
bjp-23981	142	298	*	*	PUNCT
bjp-23981	142	299	*	*	PUNCT
bjp-23981	142	300	*	*	PUNCT
bjp-23981	142	301	27.3	27.3	NUM
bjp-23981	142	302	±	±	NUM
bjp-23981	142	303	0.7	0.7	NUM
bjp-23981	142	304	13	13	NUM
bjp-23981	142	305	streptokinase	streptokinase	NOUN
bjp-23981	142	306	(	(	PUNCT
bjp-23981	142	307	30,000	30,000	NUM
bjp-23981	142	308	iu	iu	NOUN
bjp-23981	142	309	)	)	PUNCT
bjp-23981	142	310	-------46.6	-------46.6	PROPN
bjp-23981	142	311	±	±	NUM
bjp-23981	142	312	0.4	0.4	NUM
bjp-23981	142	313	acumulative	acumulative	ADJ
bjp-23981	142	314	mean	mean	NOUN
bjp-23981	142	315	data	datum	NOUN
bjp-23981	142	316	was	be	AUX
bjp-23981	142	317	analyzed	analyze	VERB
bjp-23981	142	318	by	by	ADP
bjp-23981	142	319	dunnet	dunnet	PROPN
bjp-23981	142	320	’s	’s	PART
bjp-23981	142	321	test	test	NOUN
bjp-23981	142	322	compared	compare	VERB
bjp-23981	142	323	with	with	ADP
bjp-23981	142	324	the	the	DET
bjp-23981	142	325	negative	negative	ADJ
bjp-23981	142	326	control	control	NOUN
bjp-23981	142	327	.	.	PUNCT
bjp-23981	143	1	n	n	NOUN
bjp-23981	143	2	=	=	SYM
bjp-23981	143	3	3	3	NUM
bjp-23981	143	4	;	;	PUNCT
bjp-23981	143	5	(	(	PUNCT
bjp-23981	143	6	*	*	PUNCT
bjp-23981	143	7	*	*	PUNCT
bjp-23981	143	8	*	*	PUNCT
bjp-23981	143	9	)	)	PUNCT
bjp-23981	143	10	equals	equal	VERB
bjp-23981	143	11	p<0.001	p<0.001	PROPN
bjp-23981	143	12	,	,	PUNCT
bjp-23981	143	13	(	(	PUNCT
bjp-23981	143	14	*	*	PUNCT
bjp-23981	143	15	*	*	PUNCT
bjp-23981	143	16	)	)	PUNCT
bjp-23981	143	17	equals	equal	VERB
bjp-23981	143	18	p<0.01	p<0.01	PROPN
bjp-23981	143	19	,	,	PUNCT
bjp-23981	143	20	(	(	PUNCT
bjp-23981	143	21	*	*	PUNCT
bjp-23981	143	22	)	)	PUNCT
bjp-23981	143	23	equals	equal	VERB
bjp-23981	143	24	p<0.05	p<0.05	NOUN
bjp-23981	143	25	;	;	PUNCT
bjp-23981	143	26	bresults	bresult	NOUN
bjp-23981	143	27	are	be	AUX
bjp-23981	143	28	expressed	express	VERB
bjp-23981	143	29	as	as	ADP
bjp-23981	143	30	the	the	DET
bjp-23981	143	31	mean	mean	ADJ
bjp-23981	143	32	values	value	NOUN
bjp-23981	143	33	from	from	ADP
bjp-23981	143	34	three	three	NUM
bjp-23981	143	35	parallel	parallel	ADJ
bjp-23981	143	36	experiments	experiment	NOUN
bjp-23981	143	37	±	±	NUM
bjp-23981	143	38	s.e.m	s.e.m	NOUN
bjp-23981	143	39	;	;	PUNCT
bjp-23981	143	40	cindividual	cindividual	ADJ
bjp-23981	143	41	conc	conc	NOUN
bjp-23981	143	42	.	.	PUNCT
bjp-23981	144	1	data	datum	NOUN
bjp-23981	144	2	was	be	AUX
bjp-23981	144	3	analyzed	analyze	VERB
bjp-23981	144	4	by	by	ADP
bjp-23981	144	5	dunnet	dunnet	PROPN
bjp-23981	144	6	’s	’s	PART
bjp-23981	144	7	test	test	NOUN
bjp-23981	144	8	compared	compare	VERB
bjp-23981	144	9	with	with	ADP
bjp-23981	144	10	the	the	DET
bjp-23981	144	11	negative	negative	ADJ
bjp-23981	144	12	control	control	NOUN
bjp-23981	144	13	.	.	PUNCT
bjp-23981	145	1	n	n	NOUN
bjp-23981	145	2	=	=	SYM
bjp-23981	145	3	3	3	NUM
bjp-23981	145	4	;	;	PUNCT
bjp-23981	145	5	(	(	PUNCT
bjp-23981	145	6	*	*	PUNCT
bjp-23981	145	7	*	*	PUNCT
bjp-23981	145	8	*	*	PUNCT
bjp-23981	145	9	)	)	PUNCT
bjp-23981	145	10	equals	equal	VERB
bjp-23981	145	11	p<0.001	p<0.001	PROPN
bjp-23981	145	12	,	,	PUNCT
bjp-23981	145	13	(	(	PUNCT
bjp-23981	145	14	*	*	PUNCT
bjp-23981	145	15	*	*	PUNCT
bjp-23981	145	16	)	)	PUNCT
bjp-23981	145	17	equals	equal	VERB
bjp-23981	145	18	p<0.01	p<0.01	PROPN
bjp-23981	145	19	,	,	PUNCT
bjp-23981	145	20	(	(	PUNCT
bjp-23981	145	21	*	*	PUNCT
bjp-23981	145	22	)	)	PUNCT
bjp-23981	145	23	equals	equal	VERB
bjp-23981	145	24	p<0.05	p<0.05	NOUN
bjp-23981	145	25	.	.	PUNCT
bjp-23981	146	1	bangladesh	bangladesh	PROPN
bjp-23981	146	2	j	j	PROPN
bjp-23981	146	3	pharmacol	pharmacol	PROPN
bjp-23981	146	4	2016	2016	NUM
bjp-23981	146	5	;	;	PUNCT
bjp-23981	146	6	11	11	NUM
bjp-23981	146	7	:	:	SYM
bjp-23981	146	8	67	67	NUM
bjp-23981	146	9	-	-	SYM
bjp-23981	146	10	74	74	NUM
bjp-23981	146	11	73	73	NUM
bjp-23981	146	12	author	author	NOUN
bjp-23981	146	13	info	info	NOUN
bjp-23981	146	14	b.	b.	PROPN
bjp-23981	146	15	vishwanathan	vishwanathan	PROPN
bjp-23981	146	16	(	(	PUNCT
bjp-23981	146	17	principal	principal	ADJ
bjp-23981	146	18	contact	contact	NOUN
bjp-23981	146	19	)	)	PUNCT
bjp-23981	147	1	e	e	NOUN
bjp-23981	147	2	-	-	NOUN
bjp-23981	147	3	mail	mail	NOUN
bjp-23981	147	4	:	:	PUNCT
bjp-23981	147	5	vishwanathan_b@yahoo.co.in	vishwanathan_b@yahoo.co.in	PUNCT
bjp-23981	147	6	the	the	DET
bjp-23981	147	7	confidence	confidence	NOUN
bjp-23981	147	8	interval	interval	NOUN
bjp-23981	147	9	of	of	ADP
bjp-23981	147	10	99.9	99.9	NUM
bjp-23981	147	11	%	%	NOUN
bjp-23981	147	12	with	with	ADP
bjp-23981	147	13	respect	respect	NOUN
bjp-23981	147	14	to	to	ADP
bjp-23981	147	15	control	control	NOUN
bjp-23981	147	16	.	.	PUNCT
bjp-23981	148	1	at	at	ADP
bjp-23981	148	2	the	the	DET
bjp-23981	148	3	testing	testing	NOUN
bjp-23981	148	4	strength	strength	NOUN
bjp-23981	148	5	of	of	ADP
bjp-23981	148	6	12.5	12.5	NUM
bjp-23981	148	7	µm	µm	NOUN
bjp-23981	148	8	,	,	PUNCT
bjp-23981	148	9	compounds	compound	NOUN
bjp-23981	149	1	4a-4k	4a-4k	PRON
bjp-23981	149	2	exhibited	exhibit	VERB
bjp-23981	149	3	a	a	DET
bjp-23981	149	4	mean	mean	ADJ
bjp-23981	149	5	clot	clot	NOUN
bjp-23981	149	6	lysis	lysis	NOUN
bjp-23981	149	7	ranging	range	VERB
bjp-23981	149	8	from	from	ADP
bjp-23981	149	9	16.0	16.0	NUM
bjp-23981	149	10	to	to	ADP
bjp-23981	149	11	49.0	49.0	NUM
bjp-23981	149	12	%	%	NOUN
bjp-23981	149	13	.	.	PUNCT
bjp-23981	150	1	compound	compound	NOUN
bjp-23981	150	2	4j	4j	NOUN
bjp-23981	150	3	(	(	PUNCT
bjp-23981	150	4	pyridin-3	pyridin-3	NOUN
bjp-23981	150	5	-	-	PUNCT
bjp-23981	150	6	yl	yl	NOUN
bjp-23981	150	7	)	)	PUNCT
bjp-23981	150	8	exhibited	exhibit	VERB
bjp-23981	150	9	a	a	DET
bjp-23981	150	10	mean	mean	ADJ
bjp-23981	150	11	clot	clot	NOUN
bjp-23981	150	12	lysis	lysis	NOUN
bjp-23981	150	13	value	value	NOUN
bjp-23981	150	14	of	of	ADP
bjp-23981	150	15	49.0	49.0	NUM
bjp-23981	150	16	%	%	NOUN
bjp-23981	150	17	being	be	AUX
bjp-23981	150	18	the	the	DET
bjp-23981	150	19	highest	high	ADJ
bjp-23981	150	20	and	and	CCONJ
bjp-23981	150	21	4a	4a	NOUN
bjp-23981	150	22	(	(	PUNCT
bjp-23981	150	23	phenyl	phenyl	NOUN
bjp-23981	150	24	)	)	PUNCT
bjp-23981	150	25	being	be	AUX
bjp-23981	150	26	the	the	DET
bjp-23981	150	27	least	least	ADJ
bjp-23981	150	28	with	with	ADP
bjp-23981	150	29	mean	mean	ADJ
bjp-23981	150	30	clot	clot	NOUN
bjp-23981	150	31	lysis	lysis	NOUN
bjp-23981	150	32	value	value	NOUN
bjp-23981	150	33	of	of	ADP
bjp-23981	150	34	16.0	16.0	NUM
bjp-23981	150	35	%	%	NOUN
bjp-23981	150	36	.	.	PUNCT
bjp-23981	151	1	the	the	DET
bjp-23981	151	2	statistical	statistical	ADJ
bjp-23981	151	3	analysis	analysis	NOUN
bjp-23981	151	4	of	of	ADP
bjp-23981	151	5	the	the	DET
bjp-23981	151	6	compounds	compound	NOUN
bjp-23981	151	7	thrombolytic	thrombolytic	ADJ
bjp-23981	151	8	activity	activity	NOUN
bjp-23981	151	9	highlighted	highlight	VERB
bjp-23981	151	10	that	that	SCONJ
bjp-23981	151	11	the	the	DET
bjp-23981	151	12	compounds	compound	NOUN
bjp-23981	151	13	4a-4k	4a-4k	PRON
bjp-23981	151	14	exhibited	exhibit	VERB
bjp-23981	151	15	a	a	DET
bjp-23981	151	16	significance	significance	NOUN
bjp-23981	151	17	value	value	NOUN
bjp-23981	151	18	of	of	ADP
bjp-23981	151	19	p<0.001	p<0.001	NOUN
bjp-23981	151	20	with	with	ADP
bjp-23981	151	21	respect	respect	NOUN
bjp-23981	151	22	to	to	ADP
bjp-23981	151	23	control	control	NOUN
bjp-23981	151	24	.	.	PUNCT
bjp-23981	152	1	at	at	ADP
bjp-23981	152	2	25	25	NUM
bjp-23981	152	3	µm	µm	ADP
bjp-23981	152	4	testing	testing	NOUN
bjp-23981	152	5	strength	strength	NOUN
bjp-23981	152	6	,	,	PUNCT
bjp-23981	152	7	compounds	compound	NOUN
bjp-23981	152	8	4a-4k	4a-4k	NUM
bjp-23981	152	9	exhibited	exhibit	VERB
bjp-23981	152	10	clot	clot	NOUN
bjp-23981	152	11	lysis	lysis	NOUN
bjp-23981	152	12	ranging	range	VERB
bjp-23981	152	13	from	from	ADP
bjp-23981	152	14	22.5	22.5	NUM
bjp-23981	152	15	to	to	PART
bjp-23981	152	16	56.2	56.2	NUM
bjp-23981	152	17	%	%	NOUN
bjp-23981	152	18	.	.	PUNCT
bjp-23981	153	1	compound	compound	NOUN
bjp-23981	153	2	4j	4j	NOUN
bjp-23981	153	3	(	(	PUNCT
bjp-23981	153	4	pyridin-3	pyridin-3	NOUN
bjp-23981	153	5	-	-	PUNCT
bjp-23981	153	6	yl	yl	NOUN
bjp-23981	153	7	)	)	PUNCT
bjp-23981	153	8	exhibited	exhibit	VERB
bjp-23981	153	9	the	the	DET
bjp-23981	153	10	highest	high	ADJ
bjp-23981	153	11	thrombolytic	thrombolytic	ADJ
bjp-23981	153	12	property	property	NOUN
bjp-23981	153	13	with	with	ADP
bjp-23981	153	14	mean	mean	ADJ
bjp-23981	153	15	clot	clot	NOUN
bjp-23981	153	16	lysis	lysis	NOUN
bjp-23981	153	17	value	value	NOUN
bjp-23981	153	18	of	of	ADP
bjp-23981	153	19	56.2	56.2	NUM
bjp-23981	153	20	%	%	NOUN
bjp-23981	153	21	and	and	CCONJ
bjp-23981	153	22	compound	compound	NOUN
bjp-23981	153	23	4a	4a	NOUN
bjp-23981	153	24	(	(	PUNCT
bjp-23981	153	25	phenyl	phenyl	NOUN
bjp-23981	153	26	)	)	PUNCT
bjp-23981	153	27	exhibiting	exhibit	VERB
bjp-23981	153	28	the	the	DET
bjp-23981	153	29	least	least	ADJ
bjp-23981	153	30	,	,	PUNCT
bjp-23981	153	31	with	with	ADP
bjp-23981	153	32	a	a	DET
bjp-23981	153	33	mean	mean	ADJ
bjp-23981	153	34	clot	clot	NOUN
bjp-23981	153	35	lysis	lysis	NOUN
bjp-23981	153	36	value	value	NOUN
bjp-23981	153	37	of	of	ADP
bjp-23981	153	38	22.5	22.5	NUM
bjp-23981	153	39	%	%	NOUN
bjp-23981	153	40	.	.	PUNCT
bjp-23981	154	1	the	the	DET
bjp-23981	154	2	statistical	statistical	ADJ
bjp-23981	154	3	analysis	analysis	NOUN
bjp-23981	154	4	of	of	ADP
bjp-23981	154	5	the	the	DET
bjp-23981	154	6	compounds	compound	NOUN
bjp-23981	154	7	thrombolytic	thrombolytic	ADJ
bjp-23981	154	8	activity	activity	NOUN
bjp-23981	154	9	highlighted	highlight	VERB
bjp-23981	154	10	that	that	SCONJ
bjp-23981	154	11	the	the	DET
bjp-23981	154	12	compounds	compound	NOUN
bjp-23981	154	13	4a-4k	4a-4k	PRON
bjp-23981	154	14	exhibited	exhibit	VERB
bjp-23981	154	15	a	a	DET
bjp-23981	154	16	significance	significance	NOUN
bjp-23981	154	17	value	value	NOUN
bjp-23981	154	18	of	of	ADP
bjp-23981	154	19	p<0.001	p<0.001	NOUN
bjp-23981	154	20	with	with	ADP
bjp-23981	154	21	respect	respect	NOUN
bjp-23981	154	22	to	to	ADP
bjp-23981	154	23	control	control	NOUN
bjp-23981	154	24	.	.	PUNCT
bjp-23981	155	1	conclusion	conclusion	NOUN
bjp-23981	155	2	thrombolytic	thrombolytic	ADJ
bjp-23981	155	3	evaluations	evaluation	NOUN
bjp-23981	155	4	were	be	AUX
bjp-23981	155	5	highly	highly	ADV
bjp-23981	155	6	significant	significant	ADJ
bjp-23981	155	7	and	and	CCONJ
bjp-23981	155	8	the	the	DET
bjp-23981	155	9	compounds	compound	NOUN
bjp-23981	155	10	exhibited	exhibit	VERB
bjp-23981	155	11	potent	potent	ADJ
bjp-23981	155	12	clot	clot	NOUN
bjp-23981	155	13	lysis	lysis	NOUN
bjp-23981	155	14	activity	activity	NOUN
bjp-23981	155	15	.	.	PUNCT
bjp-23981	156	1	compound	compound	NOUN
bjp-23981	156	2	4j	4j	NOUN
bjp-23981	156	3	(	(	PUNCT
bjp-23981	156	4	pyridin-3	pyridin-3	NOUN
bjp-23981	156	5	-	-	PUNCT
bjp-23981	156	6	yl	yl	NOUN
bjp-23981	156	7	)	)	PUNCT
bjp-23981	156	8	was	be	AUX
bjp-23981	156	9	most	most	ADV
bjp-23981	156	10	potent	potent	ADJ
bjp-23981	156	11	thrombolytic	thrombolytic	ADJ
bjp-23981	156	12	agent	agent	NOUN
bjp-23981	156	13	with	with	ADP
bjp-23981	156	14	a	a	DET
bjp-23981	156	15	mean	mean	ADJ
bjp-23981	156	16	ec50	ec50	PROPN
bjp-23981	156	17	value	value	NOUN
bjp-23981	156	18	16.2	16.2	NUM
bjp-23981	156	19	µm	µm	NOUN
bjp-23981	156	20	.	.	PUNCT
bjp-23981	157	1	ethical	ethical	ADJ
bjp-23981	157	2	issue	issue	NOUN
bjp-23981	157	3	all	all	DET
bjp-23981	157	4	the	the	DET
bjp-23981	157	5	animal	animal	NOUN
bjp-23981	157	6	experimental	experimental	ADJ
bjp-23981	157	7	procedures	procedure	NOUN
bjp-23981	157	8	and	and	CCONJ
bjp-23981	157	9	protocols	protocol	NOUN
bjp-23981	157	10	adapted	adapt	VERB
bjp-23981	157	11	in	in	ADP
bjp-23981	157	12	the	the	DET
bjp-23981	157	13	study	study	NOUN
bjp-23981	157	14	were	be	AUX
bjp-23981	157	15	reviewed	review	VERB
bjp-23981	157	16	and	and	CCONJ
bjp-23981	157	17	approved	approve	VERB
bjp-23981	157	18	by	by	ADP
bjp-23981	157	19	the	the	DET
bjp-23981	157	20	institutional	institutional	ADJ
bjp-23981	157	21	animal	animal	NOUN
bjp-23981	157	22	ethics	ethic	NOUN
bjp-23981	157	23	committee	committee	NOUN
bjp-23981	157	24	.	.	PUNCT
bjp-23981	158	1	the	the	DET
bjp-23981	158	2	experimental	experimental	ADJ
bjp-23981	158	3	procedures	procedure	NOUN
bjp-23981	158	4	and	and	CCONJ
bjp-23981	158	5	protocols	protocol	NOUN
bjp-23981	158	6	were	be	AUX
bjp-23981	158	7	in	in	ADP
bjp-23981	158	8	accordance	accordance	NOUN
bjp-23981	158	9	with	with	ADP
bjp-23981	158	10	the	the	DET
bjp-23981	158	11	guidelines	guideline	NOUN
bjp-23981	158	12	of	of	ADP
bjp-23981	158	13	the	the	DET
bjp-23981	158	14	cpcsea	cpcsea	NOUN
bjp-23981	158	15	,	,	PUNCT
bjp-23981	158	16	ministry	ministry	PROPN
bjp-23981	158	17	of	of	ADP
bjp-23981	158	18	forests	forest	NOUN
bjp-23981	158	19	and	and	CCONJ
bjp-23981	158	20	environment	environment	NOUN
bjp-23981	158	21	,	,	PUNCT
bjp-23981	158	22	govt	govt	PROPN
bjp-23981	158	23	.	.	PUNCT
bjp-23981	159	1	of	of	ADP
bjp-23981	159	2	india	india	PROPN
bjp-23981	159	3	.	.	PUNCT
bjp-23981	160	1	acknowledgement	acknowledgement	NOUN
bjp-23981	160	2	we	we	PRON
bjp-23981	160	3	express	express	VERB
bjp-23981	160	4	our	our	PRON
bjp-23981	160	5	gratitude	gratitude	NOUN
bjp-23981	160	6	to	to	ADP
bjp-23981	160	7	the	the	DET
bjp-23981	160	8	jss	jss	PROPN
bjp-23981	160	9	college	college	PROPN
bjp-23981	160	10	of	of	ADP
bjp-23981	160	11	pharmacy	pharmacy	NOUN
bjp-23981	160	12	,	,	PUNCT
bjp-23981	160	13	mysore	mysore	NOUN
bjp-23981	160	14	and	and	CCONJ
bjp-23981	160	15	jss	jss	PROPN
bjp-23981	160	16	university	university	PROPN
bjp-23981	160	17	for	for	ADP
bjp-23981	160	18	providing	provide	VERB
bjp-23981	160	19	us	we	PRON
bjp-23981	160	20	all	all	DET
bjp-23981	160	21	necessary	necessary	ADJ
bjp-23981	160	22	facilities	facility	NOUN
bjp-23981	160	23	.	.	PUNCT
bjp-23981	161	1	references	reference	NOUN
bjp-23981	161	2	amin	amin	PROPN
bjp-23981	161	3	km	km	PROPN
bjp-23981	161	4	,	,	PUNCT
bjp-23981	161	5	gawad	gawad	PROPN
bjp-23981	161	6	nma	nma	PROPN
bjp-23981	161	7	,	,	PUNCT
bjp-23981	161	8	rahman	rahman	PROPN
bjp-23981	161	9	dea	dea	PROPN
bjp-23981	161	10	,	,	PUNCT
bjp-23981	161	11	el	el	PROPN
bjp-23981	161	12	-	-	PUNCT
bjp-23981	161	13	ashry	ashry	PROPN
bjp-23981	161	14	mkm	mkm	PROPN
bjp-23981	161	15	.	.	PUNCT
bjp-23981	162	1	new	new	ADJ
bjp-23981	162	2	series	series	NOUN
bjp-23981	162	3	of	of	ADP
bjp-23981	162	4	6	6	NUM
bjp-23981	162	5	-	-	PUNCT
bjp-23981	162	6	substituted	substitute	VERB
bjp-23981	162	7	coumarin	coumarin	NOUN
bjp-23981	162	8	derivatives	derivative	NOUN
bjp-23981	162	9	as	as	ADP
bjp-23981	162	10	effective	effective	ADJ
bjp-23981	162	11	factor	factor	NOUN
bjp-23981	162	12	xa	xa	NOUN
bjp-23981	162	13	inhibitors	inhibitor	NOUN
bjp-23981	162	14	:	:	PUNCT
bjp-23981	162	15	synthesis	synthesis	NOUN
bjp-23981	162	16	,	,	PUNCT
bjp-23981	162	17	in	in	ADP
bjp-23981	162	18	vivo	vivo	ADJ
bjp-23981	162	19	antithrombotic	antithrombotic	ADJ
bjp-23981	162	20	evaluation	evaluation	NOUN
bjp-23981	162	21	and	and	CCONJ
bjp-23981	162	22	molecular	molecular	ADJ
bjp-23981	162	23	docking	docking	NOUN
bjp-23981	162	24	.	.	PUNCT
bjp-23981	163	1	bioorg	bioorg	PROPN
bjp-23981	163	2	chem	chem	NOUN
bjp-23981	163	3	.	.	PUNCT
bjp-23981	164	1	2014	2014	NUM
bjp-23981	164	2	;	;	PUNCT
bjp-23981	164	3	52	52	NUM
bjp-23981	164	4	:	:	SYM
bjp-23981	164	5	31	31	NUM
bjp-23981	164	6	–	–	SYM
bjp-23981	164	7	43	43	NUM
bjp-23981	164	8	.	.	PUNCT
bjp-23981	165	1	ertl	ertl	PROPN
bjp-23981	165	2	p	p	PROPN
bjp-23981	165	3	,	,	PUNCT
bjp-23981	165	4	rohde	rohde	PROPN
bjp-23981	165	5	b	b	PROPN
bjp-23981	165	6	,	,	PUNCT
bjp-23981	165	7	selzer	selzer	PROPN
bjp-23981	165	8	p	p	NOUN
bjp-23981	165	9	,	,	PUNCT
bjp-23981	165	10	fast	fast	ADJ
bjp-23981	165	11	calculation	calculation	NOUN
bjp-23981	165	12	of	of	ADP
bjp-23981	165	13	molecular	molecular	ADJ
bjp-23981	165	14	polar	polar	ADJ
bjp-23981	165	15	surface	surface	NOUN
bjp-23981	165	16	area	area	NOUN
bjp-23981	165	17	as	as	ADP
bjp-23981	165	18	a	a	DET
bjp-23981	165	19	sum	sum	NOUN
bjp-23981	165	20	of	of	ADP
bjp-23981	165	21	fragment	fragment	NOUN
bjp-23981	165	22	-	-	PUNCT
bjp-23981	165	23	based	base	VERB
bjp-23981	165	24	contributions	contribution	NOUN
bjp-23981	165	25	and	and	CCONJ
bjp-23981	165	26	its	its	PRON
bjp-23981	165	27	application	application	NOUN
bjp-23981	165	28	to	to	ADP
bjp-23981	165	29	the	the	DET
bjp-23981	165	30	prediction	prediction	NOUN
bjp-23981	165	31	of	of	ADP
bjp-23981	165	32	drug	drug	NOUN
bjp-23981	165	33	transport	transport	NOUN
bjp-23981	165	34	properties	property	NOUN
bjp-23981	165	35	.	.	PUNCT
bjp-23981	166	1	j	j	PROPN
bjp-23981	166	2	med	med	PROPN
bjp-23981	166	3	chem	chem	NOUN
bjp-23981	166	4	.	.	PUNCT
bjp-23981	167	1	2000	2000	NUM
bjp-23981	167	2	;	;	PUNCT
bjp-23981	167	3	43	43	NUM
bjp-23981	167	4	:	:	PUNCT
bjp-23981	167	5	3714	3714	NUM
bjp-23981	167	6	-	-	SYM
bjp-23981	167	7	17	17	NUM
bjp-23981	167	8	godfrey	godfrey	PROPN
bjp-23981	167	9	em	em	PRON
bjp-23981	167	10	,	,	PUNCT
bjp-23981	167	11	godfrey	godfrey	PROPN
bjp-23981	167	12	al	al	PROPN
bjp-23981	167	13	,	,	PUNCT
bjp-23981	167	14	perry	perry	PROPN
bjp-23981	167	15	dj	dj	PROPN
bjp-23981	167	16	,	,	PUNCT
bjp-23981	167	17	shawa	shawa	PROPN
bjp-23981	167	18	as	as	ADP
bjp-23981	167	19	.	.	PUNCT
bjp-23981	168	1	do	do	AUX
bjp-23981	168	2	n’t	not	PART
bjp-23981	168	3	be	be	AUX
bjp-23981	168	4	a	a	DET
bjp-23981	168	5	clot	clot	NOUN
bjp-23981	168	6	:	:	PUNCT
bjp-23981	168	7	a	a	DET
bjp-23981	168	8	radiologist	radiologist	NOUN
bjp-23981	168	9	’s	’s	PART
bjp-23981	168	10	guide	guide	NOUN
bjp-23981	168	11	to	to	ADP
bjp-23981	168	12	haemostasis	haemostasis	NOUN
bjp-23981	168	13	including	include	VERB
bjp-23981	168	14	novel	novel	ADJ
bjp-23981	168	15	antiplatelet	antiplatelet	NOUN
bjp-23981	168	16	and	and	CCONJ
bjp-23981	168	17	anticoagulant	anticoagulant	ADJ
bjp-23981	168	18	therapy	therapy	NOUN
bjp-23981	168	19	.	.	PUNCT
bjp-23981	169	1	clin	clin	PROPN
bjp-23981	169	2	rad	rad	PROPN
bjp-23981	169	3	.	.	PROPN
bjp-23981	169	4	2011	2011	NUM
bjp-23981	169	5	;	;	PUNCT
bjp-23981	169	6	66	66	NUM
bjp-23981	169	7	:	:	PUNCT
bjp-23981	169	8	693	693	NUM
bjp-23981	169	9	-	-	SYM
bjp-23981	169	10	700	700	NUM
bjp-23981	169	11	.	.	PUNCT
bjp-23981	170	1	meschia	meschia	PROPN
bjp-23981	170	2	jf	jf	PROPN
bjp-23981	170	3	,	,	PUNCT
bjp-23981	170	4	miller	miller	PROPN
bjp-23981	170	5	da	da	PROPN
bjp-23981	170	6	,	,	PUNCT
bjp-23981	170	7	brott	brott	PROPN
bjp-23981	170	8	tg	tg	PROPN
bjp-23981	170	9	.	.	PUNCT
bjp-23981	171	1	thrombolytic	thrombolytic	ADJ
bjp-23981	171	2	treatment	treatment	NOUN
bjp-23981	171	3	of	of	ADP
bjp-23981	171	4	acute	acute	ADJ
bjp-23981	171	5	ischemic	ischemic	ADJ
bjp-23981	171	6	stroke	stroke	NOUN
bjp-23981	171	7	.	.	PUNCT
bjp-23981	172	1	mayo	mayo	PROPN
bjp-23981	172	2	clin	clin	PROPN
bjp-23981	172	3	proc	proc	PROPN
bjp-23981	172	4	.	.	PUNCT
bjp-23981	173	1	2002	2002	NUM
bjp-23981	173	2	;	;	PUNCT
bjp-23981	173	3	77	77	NUM
bjp-23981	173	4	:	:	PUNCT
bjp-23981	173	5	542	542	NUM
bjp-23981	173	6	-	-	SYM
bjp-23981	173	7	51	51	NUM
bjp-23981	173	8	.	.	PUNCT
bjp-23981	174	1	murray	murray	PROPN
bjp-23981	174	2	cj	cj	PROPN
bjp-23981	174	3	,	,	PUNCT
bjp-23981	174	4	lopez	lopez	PROPN
bjp-23981	174	5	ad	ad	NOUN
bjp-23981	174	6	.	.	PUNCT
bjp-23981	175	1	global	global	ADJ
bjp-23981	175	2	mortality	mortality	NOUN
bjp-23981	175	3	,	,	PUNCT
bjp-23981	175	4	disability	disability	NOUN
bjp-23981	175	5	,	,	PUNCT
bjp-23981	175	6	and	and	CCONJ
bjp-23981	175	7	the	the	DET
bjp-23981	175	8	contribution	contribution	NOUN
bjp-23981	175	9	of	of	ADP
bjp-23981	175	10	risk	risk	NOUN
bjp-23981	175	11	factors	factor	NOUN
bjp-23981	175	12	:	:	PUNCT
bjp-23981	175	13	global	global	ADJ
bjp-23981	175	14	burden	burden	NOUN
bjp-23981	175	15	of	of	ADP
bjp-23981	175	16	disease	disease	NOUN
bjp-23981	175	17	study	study	NOUN
bjp-23981	175	18	.	.	PUNCT
bjp-23981	176	1	lancet	lancet	PROPN
bjp-23981	176	2	1997	1997	NUM
bjp-23981	176	3	;	;	PUNCT
bjp-23981	176	4	349	349	NUM
bjp-23981	176	5	:	:	PUNCT
bjp-23981	176	6	1436–42	1436–42	NUM
bjp-23981	176	7	.	.	PUNCT
bjp-23981	177	1	prasad	prasad	PROPN
bjp-23981	177	2	s	s	PROPN
bjp-23981	177	3	,	,	PUNCT
bjp-23981	177	4	kashyap	kashyap	PROPN
bjp-23981	177	5	rs	rs	PROPN
bjp-23981	177	6	,	,	PUNCT
bjp-23981	177	7	deopujari	deopujari	PROPN
bjp-23981	177	8	jy	jy	PROPN
bjp-23981	177	9	,	,	PUNCT
bjp-23981	177	10	purohit	purohit	PROPN
bjp-23981	177	11	hj	hj	PROPN
bjp-23981	177	12	,	,	PUNCT
bjp-23981	177	13	taori	taori	PRON
bjp-23981	177	14	gm	gm	PROPN
bjp-23981	177	15	,	,	PUNCT
bjp-23981	177	16	daginawala	daginawala	PROPN
bjp-23981	177	17	hf	hf	PROPN
bjp-23981	177	18	.	.	PUNCT
bjp-23981	178	1	development	development	NOUN
bjp-23981	178	2	of	of	ADP
bjp-23981	178	3	an	an	DET
bjp-23981	178	4	in	in	ADP
bjp-23981	178	5	vitro	vitro	X
bjp-23981	178	6	model	model	NOUN
bjp-23981	178	7	to	to	PART
bjp-23981	178	8	study	study	VERB
bjp-23981	178	9	clot	clot	NOUN
bjp-23981	178	10	lysis	lysis	NOUN
bjp-23981	178	11	activity	activity	NOUN
bjp-23981	178	12	of	of	ADP
bjp-23981	178	13	thrombolytic	thrombolytic	ADJ
bjp-23981	178	14	drugs	drug	NOUN
bjp-23981	178	15	.	.	PUNCT
bjp-23981	179	1	thrombosis	thrombosis	NOUN
bjp-23981	179	2	2006	2006	NUM
bjp-23981	179	3	;	;	PUNCT
bjp-23981	179	4	4	4	NUM
bjp-23981	179	5	:	:	SYM
bjp-23981	179	6	1	1	NUM
bjp-23981	179	7	-	-	SYM
bjp-23981	179	8	4	4	NUM
bjp-23981	179	9	.	.	PUNCT
bjp-23981	179	10	sobel	sobel	NOUN
bjp-23981	179	11	be	be	AUX
bjp-23981	179	12	.	.	PUNCT
bjp-23981	180	1	the	the	DET
bjp-23981	180	2	management	management	NOUN
bjp-23981	180	3	of	of	ADP
bjp-23981	180	4	acute	acute	ADJ
bjp-23981	180	5	myocardial	myocardial	ADJ
bjp-23981	180	6	infarction	infarction	NOUN
bjp-23981	180	7	.	.	PUNCT
bjp-23981	181	1	in	in	ADP
bjp-23981	181	2	:	:	PUNCT
bjp-23981	181	3	heart	heart	NOUN
bjp-23981	181	4	disease	disease	NOUN
bjp-23981	181	5	:	:	PUNCT
bjp-23981	181	6	a	a	DET
bjp-23981	181	7	textbook	textbook	NOUN
bjp-23981	181	8	of	of	ADP
bjp-23981	181	9	cardiovascular	cardiovascular	ADJ
bjp-23981	181	10	medicine	medicine	NOUN
bjp-23981	181	11	.	.	PUNCT
bjp-23981	182	1	braunwald	braunwald	PROPN
bjp-23981	182	2	e	e	PROPN
bjp-23981	182	3	(	(	PUNCT
bjp-23981	182	4	ed	ed	NOUN
bjp-23981	182	5	)	)	PUNCT
bjp-23981	182	6	.	.	PUNCT
bjp-23981	183	1	2nd	2nd	ADJ
bjp-23981	183	2	ed	ed	NOUN
bjp-23981	183	3	.	.	PUNCT
bjp-23981	183	4	philadelphia	philadelphia	PROPN
bjp-23981	183	5	,	,	PUNCT
bjp-23981	183	6	wb	wb	PROPN
bjp-23981	183	7	saunders	saunder	NOUN
bjp-23981	183	8	,	,	PUNCT
bjp-23981	183	9	1984	1984	NUM
bjp-23981	183	10	,	,	PUNCT
bjp-23981	183	11	pp	pp	ADP
bjp-23981	183	12	1301	1301	NUM
bjp-23981	183	13	-	-	SYM
bjp-23981	183	14	33	33	NUM
bjp-23981	183	15	.	.	PUNCT
bjp-23981	184	1	vishwanathan	vishwanathan	PROPN
bjp-23981	184	2	b	b	PROPN
bjp-23981	184	3	,	,	PUNCT
bjp-23981	184	4	gurupadayya	gurupadayya	PROPN
bjp-23981	184	5	bm	bm	PROPN
bjp-23981	184	6	.	.	PUNCT
bjp-23981	184	7	synthesis	synthesis	NOUN
bjp-23981	184	8	and	and	CCONJ
bjp-23981	184	9	characterization	characterization	NOUN
bjp-23981	184	10	of	of	ADP
bjp-23981	184	11	novel	novel	ADJ
bjp-23981	184	12	oxadiazole	oxadiazole	NOUN
bjp-23981	184	13	derivatives	derivative	NOUN
bjp-23981	184	14	from	from	ADP
bjp-23981	184	15	benzimidazole	benzimidazole	PROPN
bjp-23981	184	16	.	.	PUNCT
bjp-23981	185	1	j	j	PROPN
bjp-23981	185	2	korean	korean	ADJ
bjp-23981	185	3	chem	chem	PROPN
bjp-23981	185	4	soc	soc	NOUN
bjp-23981	185	5	.	.	PUNCT
bjp-23981	186	1	2014	2014	NUM
bjp-23981	186	2	;	;	PUNCT
bjp-23981	187	1	58	58	NUM
bjp-23981	187	2	:	:	PUNCT
bjp-23981	187	3	450	450	NUM
bjp-23981	187	4	-	-	SYM
bjp-23981	187	5	55	55	NUM
bjp-23981	187	6	.	.	PUNCT
bjp-23981	188	1	74	74	NUM
bjp-23981	188	2	bangladesh	bangladesh	PROPN
bjp-23981	188	3	j	j	PROPN
bjp-23981	188	4	pharmacol	pharmacol	PROPN
bjp-23981	188	5	2016	2016	NUM
bjp-23981	188	6	;	;	PUNCT
bjp-23981	188	7	11	11	NUM
bjp-23981	188	8	:	:	SYM
bjp-23981	188	9	67	67	NUM
bjp-23981	188	10	-	-	SYM
bjp-23981	188	11	74	74	NUM
bjp-23981	188	12	your	your	PRON
bjp-23981	188	13	feedback	feedback	NOUN
bjp-23981	188	14	about	about	ADP
bjp-23981	188	15	this	this	DET
bjp-23981	188	16	paper	paper	NOUN
bjp-23981	188	17	1	1	NUM
bjp-23981	188	18	.	.	PUNCT
bjp-23981	188	19	number	number	NOUN
bjp-23981	188	20	of	of	ADP
bjp-23981	188	21	times	time	NOUN
bjp-23981	188	22	you	you	PRON
bjp-23981	188	23	have	have	AUX
bjp-23981	188	24	read	read	VERB
bjp-23981	188	25	this	this	DET
bjp-23981	188	26	paper	paper	NOUN
bjp-23981	188	27	2	2	NUM
bjp-23981	188	28	.	.	PUNCT
bjp-23981	188	29	quality	quality	NOUN
bjp-23981	188	30	of	of	ADP
bjp-23981	188	31	paper	paper	NOUN
bjp-23981	188	32	3	3	X
bjp-23981	188	33	.	.	PUNCT
bjp-23981	189	1	your	your	PRON
bjp-23981	189	2	comments	comment	NOUN
bjp-23981	189	3	dateprinted	dateprinte	VERB
bjp-23981	189	4	:	:	PUNCT
bjp-23981	189	5	this	this	DET
bjp-23981	189	6	article	article	NOUN
bjp-23981	189	7	was	be	AUX
bjp-23981	189	8	downloaded	download	VERB
bjp-23981	189	9	by	by	ADP
bjp-23981	189	10	you	you	PRON
bjp-23981	189	11	on	on	ADP
bjp-23981	189	12	:	:	PUNCT
bjp-23981	189	13	jun	jun	PROPN
bjp-23981	189	14	24	24	NUM
bjp-23981	189	15	,	,	PUNCT
bjp-23981	189	16	2017	2017	NUM
bjp-23981	189	17	text2	text2	NOUN
bjp-23981	189	18	:	:	PUNCT
bjp-23981	189	19	dropdown3	dropdown3	PROPN
bjp-23981	189	20	:	:	PUNCT
bjp-23981	190	1	[	[	X
bjp-23981	190	2	click	click	NOUN
bjp-23981	190	3	]	]	PUNCT
bjp-23981	190	4	dropdown4	dropdown4	PROPN
bjp-23981	190	5	:	:	PUNCT
bjp-23981	191	1	[	[	X
bjp-23981	191	2	0	0	X
bjp-23981	191	3	]	]	PUNCT