id	sid	tid	token	lemma	pos
bjp-61292	1	1	bangladesh	bangladesh	PROPN
bjp-61292	1	2	journal	journal	PROPN
bjp-61292	1	3	of	of	ADP
bjp-61292	1	4	pharmacology	pharmacology	NOUN
bjp-61292	1	5	research	research	NOUN
bjp-61292	1	6	article	article	NOUN
bjp-61292	1	7	zoledronic	zoledronic	ADJ
bjp-61292	1	8	acid	acid	PROPN
bjp-61292	1	9	inhibits	inhibit	VERB
bjp-61292	1	10	the	the	DET
bjp-61292	1	11	bone	bone	NOUN
bjp-61292	1	12	metastasis	metastasis	NOUN
bjp-61292	1	13	of	of	ADP
bjp-61292	1	14	breast	breast	NOUN
bjp-61292	1	15	cancer	cancer	NOUN
bjp-61292	1	16	by	by	ADP
bjp-61292	1	17	repressing	repress	VERB
bjp-61292	1	18	exosome	exosome	NOUN
bjp-61292	1	19	-	-	PUNCT
bjp-61292	1	20	loaded	load	VERB
bjp-61292	1	21	dkk1	dkk1	PROPN
bjp-61292	1	22	bjp	bjp	PROPN
bjp-61292	1	23	introduction	introduction	NOUN
bjp-61292	1	24	a	a	DET
bjp-61292	1	25	high	high	ADJ
bjp-61292	1	26	possibility	possibility	NOUN
bjp-61292	1	27	of	of	ADP
bjp-61292	1	28	bone	bone	NOUN
bjp-61292	1	29	metastasis	metastasis	NOUN
bjp-61292	1	30	is	be	AUX
bjp-61292	1	31	reported	report	VERB
bjp-61292	1	32	in	in	ADP
bjp-61292	1	33	breast	breast	NOUN
bjp-61292	1	34	cancer	cancer	NOUN
bjp-61292	1	35	,	,	PUNCT
bjp-61292	1	36	which	which	PRON
bjp-61292	1	37	is	be	AUX
bjp-61292	1	38	observed	observe	VERB
bjp-61292	1	39	in	in	ADP
bjp-61292	1	40	approximately	approximately	ADV
bjp-61292	1	41	7080	7080	NUM
bjp-61292	1	42	%	%	NOUN
bjp-61292	1	43	of	of	ADP
bjp-61292	1	44	advanced	advanced	ADJ
bjp-61292	1	45	breast	breast	NOUN
bjp-61292	1	46	cancer	cancer	NOUN
bjp-61292	1	47	patients	patient	NOUN
bjp-61292	1	48	(	(	PUNCT
bjp-61292	1	49	mundy	mundy	NOUN
bjp-61292	1	50	,	,	PUNCT
bjp-61292	1	51	2002	2002	NUM
bjp-61292	1	52	;	;	PUNCT
bjp-61292	1	53	weilbaecher	weilbaecher	NOUN
bjp-61292	1	54	et	et	PROPN
bjp-61292	1	55	al	al	PROPN
bjp-61292	1	56	.	.	PROPN
bjp-61292	1	57	,	,	PUNCT
bjp-61292	1	58	2011	2011	NUM
bjp-61292	1	59	)	)	PUNCT
bjp-61292	1	60	.	.	PUNCT
bjp-61292	2	1	the	the	DET
bjp-61292	2	2	bone	bone	NOUN
bjp-61292	2	3	metastases	metastasis	NOUN
bjp-61292	2	4	in	in	ADP
bjp-61292	2	5	breast	breast	NOUN
bjp-61292	2	6	cancer	cancer	NOUN
bjp-61292	2	7	belong	belong	VERB
bjp-61292	2	8	to	to	ADP
bjp-61292	2	9	osteolytic	osteolytic	ADJ
bjp-61292	2	10	metastases	metastasis	NOUN
bjp-61292	2	11	with	with	ADP
bjp-61292	2	12	a	a	DET
bjp-61292	2	13	series	series	NOUN
bjp-61292	2	14	of	of	ADP
bjp-61292	2	15	complications	complication	NOUN
bjp-61292	2	16	,	,	PUNCT
bjp-61292	2	17	such	such	ADJ
bjp-61292	2	18	as	as	ADP
bjp-61292	2	19	progressive	progressive	ADJ
bjp-61292	2	20	refractory	refractory	NOUN
bjp-61292	2	21	bone	bone	NOUN
bjp-61292	2	22	pain	pain	NOUN
bjp-61292	2	23	,	,	PUNCT
bjp-61292	2	24	pathological	pathological	ADJ
bjp-61292	2	25	fracture	fracture	NOUN
bjp-61292	2	26	,	,	PUNCT
bjp-61292	2	27	osteoporosis	osteoporosis	NOUN
bjp-61292	2	28	,	,	PUNCT
bjp-61292	2	29	spinal	spinal	ADJ
bjp-61292	2	30	cord	cord	NOUN
bjp-61292	2	31	compression	compression	NOUN
bjp-61292	2	32	,	,	PUNCT
bjp-61292	2	33	and	and	CCONJ
bjp-61292	2	34	hypercalcemia	hypercalcemia	NOUN
bjp-61292	2	35	.	.	PUNCT
bjp-61292	3	1	the	the	DET
bjp-61292	3	2	life	life	NOUN
bjp-61292	3	3	quality	quality	NOUN
bjp-61292	3	4	of	of	ADP
bjp-61292	3	5	patients	patient	NOUN
bjp-61292	3	6	is	be	AUX
bjp-61292	3	7	significantly	significantly	ADV
bjp-61292	3	8	influenced	influence	VERB
bjp-61292	3	9	by	by	ADP
bjp-61292	3	10	the	the	DET
bjp-61292	3	11	bone	bone	NOUN
bjp-61292	3	12	metastasis	metastasis	NOUN
bjp-61292	3	13	and	and	CCONJ
bjp-61292	3	14	the	the	DET
bjp-61292	3	15	5	5	NUM
bjp-61292	3	16	-	-	PUNCT
bjp-61292	3	17	year	year	NOUN
bjp-61292	3	18	survival	survival	NOUN
bjp-61292	3	19	rate	rate	NOUN
bjp-61292	3	20	has	have	AUX
bjp-61292	3	21	been	be	AUX
bjp-61292	3	22	significantly	significantly	ADV
bjp-61292	3	23	decreased	decrease	VERB
bjp-61292	3	24	(	(	PUNCT
bjp-61292	3	25	mundy	mundy	NOUN
bjp-61292	3	26	,	,	PUNCT
bjp-61292	3	27	2002	2002	NUM
bjp-61292	3	28	)	)	PUNCT
bjp-61292	3	29	.	.	PUNCT
bjp-61292	4	1	in	in	ADP
bjp-61292	4	2	the	the	DET
bjp-61292	4	3	normal	normal	ADJ
bjp-61292	4	4	bone	bone	NOUN
bjp-61292	4	5	microenvironment	microenvironment	NOUN
bjp-61292	4	6	,	,	PUNCT
bjp-61292	4	7	the	the	DET
bjp-61292	4	8	bone	bone	NOUN
bjp-61292	4	9	formation	formation	NOUN
bjp-61292	4	10	mediated	mediate	VERB
bjp-61292	4	11	by	by	ADP
bjp-61292	4	12	osteoblasts	osteoblast	NOUN
bjp-61292	4	13	and	and	CCONJ
bjp-61292	4	14	the	the	DET
bjp-61292	4	15	bone	bone	NOUN
bjp-61292	4	16	disruption	disruption	NOUN
bjp-61292	4	17	induced	induce	VERB
bjp-61292	4	18	by	by	ADP
bjp-61292	4	19	osteoclasts	osteoclast	NOUN
bjp-61292	4	20	is	be	AUX
bjp-61292	4	21	maintained	maintain	VERB
bjp-61292	4	22	with	with	ADP
bjp-61292	4	23	a	a	DET
bjp-61292	4	24	dynamic	dynamic	ADJ
bjp-61292	4	25	equilibrium	equilibrium	NOUN
bjp-61292	4	26	(	(	PUNCT
bjp-61292	4	27	roodman	roodman	NOUN
bjp-61292	4	28	and	and	CCONJ
bjp-61292	4	29	silbermann	silbermann	NOUN
bjp-61292	4	30	,	,	PUNCT
bjp-61292	4	31	2015	2015	NUM
bjp-61292	4	32	)	)	PUNCT
bjp-61292	4	33	.	.	PUNCT
bjp-61292	5	1	osteoclasts	osteoclast	NOUN
bjp-61292	5	2	originate	originate	VERB
bjp-61292	5	3	from	from	ADP
bjp-61292	5	4	the	the	DET
bjp-61292	5	5	monocyte	monocyte	ADJ
bjp-61292	5	6	-	-	PUNCT
bjp-61292	5	7	macrophage	macrophage	NOUN
bjp-61292	5	8	system	system	NOUN
bjp-61292	5	9	and	and	CCONJ
bjp-61292	5	10	are	be	AUX
bjp-61292	5	11	only	only	ADV
bjp-61292	5	12	cells	cell	NOUN
bjp-61292	5	13	with	with	ADP
bjp-61292	5	14	osteolytic	osteolytic	ADJ
bjp-61292	5	15	destructive	destructive	ADJ
bjp-61292	5	16	function	function	NOUN
bjp-61292	5	17	(	(	PUNCT
bjp-61292	5	18	clezardin	clezardin	VERB
bjp-61292	5	19	2011	2011	NUM
bjp-61292	5	20	)	)	PUNCT
bjp-61292	5	21	.	.	PUNCT
bjp-61292	6	1	mature	mature	ADJ
bjp-61292	6	2	osteoclasts	osteoclast	NOUN
bjp-61292	6	3	are	be	AUX
bjp-61292	6	4	characterized	characterize	VERB
bjp-61292	6	5	by	by	ADP
bjp-61292	6	6	multiple	multiple	ADJ
bjp-61292	6	7	nuclei	nucleus	NOUN
bjp-61292	6	8	and	and	CCONJ
bjp-61292	6	9	large	large	ADJ
bjp-61292	6	10	size	size	NOUN
bjp-61292	6	11	,	,	PUNCT
bjp-61292	6	12	which	which	PRON
bjp-61292	6	13	induce	induce	VERB
bjp-61292	6	14	osteolysis	osteolysis	NOUN
bjp-61292	6	15	destruction	destruction	NOUN
bjp-61292	6	16	by	by	ADP
bjp-61292	6	17	secreting	secrete	VERB
bjp-61292	6	18	acids	acid	NOUN
bjp-61292	6	19	and	and	CCONJ
bjp-61292	6	20	proteases	protease	NOUN
bjp-61292	6	21	(	(	PUNCT
bjp-61292	6	22	boyce	boyce	PROPN
bjp-61292	6	23	,	,	PUNCT
bjp-61292	6	24	2013	2013	NUM
bjp-61292	6	25	)	)	PUNCT
bjp-61292	6	26	.	.	PUNCT
bjp-61292	7	1	currently	currently	ADV
bjp-61292	7	2	,	,	PUNCT
bjp-61292	7	3	several	several	ADJ
bjp-61292	7	4	important	important	ADJ
bjp-61292	7	5	factors	factor	NOUN
bjp-61292	7	6	have	have	AUX
bjp-61292	7	7	been	be	AUX
bjp-61292	7	8	found	find	VERB
bjp-61292	7	9	involved	involve	VERB
bjp-61292	7	10	in	in	ADP
bjp-61292	7	11	the	the	DET
bjp-61292	7	12	molecular	molecular	ADJ
bjp-61292	7	13	mechanism	mechanism	NOUN
bjp-61292	7	14	of	of	ADP
bjp-61292	7	15	inducing	induce	VERB
bjp-61292	7	16	the	the	DET
bjp-61292	7	17	differentiation	differentiation	NOUN
bjp-61292	7	18	and	and	CCONJ
bjp-61292	7	19	maturity	maturity	NOUN
bjp-61292	7	20	of	of	ADP
bjp-61292	7	21	osteoclasts	osteoclast	NOUN
bjp-61292	7	22	,	,	PUNCT
bjp-61292	7	23	such	such	ADJ
bjp-61292	7	24	as	as	ADP
bjp-61292	7	25	dickkopf-1	dickkopf-1	PROPN
bjp-61292	7	26	(	(	PUNCT
bjp-61292	7	27	dkk-1	dkk-1	NUM
bjp-61292	7	28	)	)	PUNCT
bjp-61292	7	29	,	,	PUNCT
bjp-61292	7	30	rankl	rankl	VERB
bjp-61292	7	31	,	,	PUNCT
bjp-61292	7	32	and	and	CCONJ
bjp-61292	7	33	m	m	NOUN
bjp-61292	7	34	-	-	ADJ
bjp-61292	7	35	csf	csf	ADJ
bjp-61292	7	36	(	(	PUNCT
bjp-61292	7	37	miyamoto	miyamoto	NOUN
bjp-61292	7	38	,	,	PUNCT
bjp-61292	7	39	2011	2011	NUM
bjp-61292	7	40	)	)	PUNCT
bjp-61292	7	41	.	.	PUNCT
bjp-61292	8	1	as	as	ADP
bjp-61292	8	2	the	the	DET
bjp-61292	8	3	endogenous	endogenous	ADJ
bjp-61292	8	4	inhibitor	inhibitor	NOUN
bjp-61292	8	5	for	for	ADP
bjp-61292	8	6	the	the	DET
bjp-61292	8	7	wnt	wnt	PROPN
bjp-61292	8	8	signal	signal	PROPN
bjp-61292	8	9	pathway	pathway	NOUN
bjp-61292	8	10	,	,	PUNCT
bjp-61292	8	11	dkk	dkk	PROPN
bjp-61292	8	12	-1	-1	PROPN
bjp-61292	8	13	is	be	AUX
bjp-61292	8	14	reported	report	VERB
bjp-61292	8	15	to	to	PART
bjp-61292	8	16	suppress	suppress	VERB
bjp-61292	8	17	bone	bone	NOUN
bjp-61292	8	18	formation	formation	NOUN
bjp-61292	8	19	by	by	ADP
bjp-61292	8	20	inhibiting	inhibit	VERB
bjp-61292	8	21	the	the	DET
bjp-61292	8	22	differentiation	differentiation	NOUN
bjp-61292	8	23	from	from	ADP
bjp-61292	8	24	adipocytes	adipocyte	NOUN
bjp-61292	8	25	to	to	ADP
bjp-61292	8	26	osteoblasts	osteoblast	NOUN
bjp-61292	8	27	(	(	PUNCT
bjp-61292	8	28	chen	chen	PROPN
bjp-61292	8	29	et	et	PROPN
bjp-61292	8	30	al	al	PROPN
bjp-61292	8	31	.	.	PROPN
bjp-61292	8	32	,	,	PUNCT
bjp-61292	8	33	2007	2007	NUM
bjp-61292	8	34	)	)	PUNCT
bjp-61292	8	35	and	and	CCONJ
bjp-61292	8	36	activates	activate	VERB
bjp-61292	8	37	osteoclasts	osteoclast	NOUN
bjp-61292	8	38	to	to	PART
bjp-61292	8	39	trigger	trigger	VERB
bjp-61292	8	40	osteolysis	osteolysis	NOUN
bjp-61292	8	41	destruction	destruction	NOUN
bjp-61292	8	42	(	(	PUNCT
bjp-61292	8	43	qiang	qiang	PROPN
bjp-61292	8	44	et	et	PROPN
bjp-61292	8	45	al	al	PROPN
bjp-61292	8	46	.	.	PROPN
bjp-61292	8	47	,	,	PUNCT
bjp-61292	8	48	2010	2010	NUM
bjp-61292	8	49	)	)	PUNCT
bjp-61292	8	50	.	.	PUNCT
bjp-61292	9	1	dkk-1	dkk-1	PUNCT
bjp-61292	9	2	has	have	AUX
bjp-61292	9	3	been	be	AUX
bjp-61292	9	4	regarded	regard	VERB
bjp-61292	9	5	as	as	ADP
bjp-61292	9	6	an	an	DET
bjp-61292	9	7	important	important	ADJ
bjp-61292	9	8	biomarker	biomarker	NOUN
bjp-61292	9	9	for	for	ADP
bjp-61292	9	10	bone	bone	NOUN
bjp-61292	9	11	loss	loss	NOUN
bjp-61292	9	12	(	(	PUNCT
bjp-61292	9	13	huang	huang	PROPN
bjp-61292	9	14	et	et	PROPN
bjp-61292	9	15	al	al	PROPN
bjp-61292	9	16	.	.	PROPN
bjp-61292	9	17	,	,	PUNCT
bjp-61292	9	18	2018	2018	NUM
bjp-61292	9	19	)	)	PUNCT
bjp-61292	9	20	.	.	PUNCT
bjp-61292	10	1	the	the	DET
bjp-61292	10	2	development	development	NOUN
bjp-61292	10	3	of	of	ADP
bjp-61292	10	4	bone	bone	NOUN
bjp-61292	10	5	metastasis	metastasis	NOUN
bjp-61292	10	6	is	be	AUX
bjp-61292	10	7	closely	closely	ADV
bjp-61292	10	8	related	relate	VERB
bjp-61292	10	9	to	to	ADP
bjp-61292	10	10	the	the	DET
bjp-61292	10	11	regulatory	regulatory	ADJ
bjp-61292	10	12	effects	effect	NOUN
bjp-61292	10	13	of	of	ADP
bjp-61292	10	14	cancer	cancer	NOUN
bjp-61292	10	15	cells	cell	NOUN
bjp-61292	10	16	on	on	ADP
bjp-61292	10	17	the	the	DET
bjp-61292	10	18	bone	bone	NOUN
bjp-61292	10	19	abstract	abstract	NOUN
bjp-61292	10	20	this	this	DET
bjp-61292	10	21	study	study	NOUN
bjp-61292	10	22	is	be	AUX
bjp-61292	10	23	designed	design	VERB
bjp-61292	10	24	to	to	PART
bjp-61292	10	25	investigate	investigate	VERB
bjp-61292	10	26	the	the	DET
bjp-61292	10	27	mechanism	mechanism	NOUN
bjp-61292	10	28	underlying	underlie	VERB
bjp-61292	10	29	zoledronic	zoledronic	ADJ
bjp-61292	10	30	acid	acid	NOUN
bjp-61292	10	31	for	for	ADP
bjp-61292	10	32	the	the	DET
bjp-61292	10	33	bone	bone	NOUN
bjp-61292	10	34	metastasis	metastasis	NOUN
bjp-61292	10	35	of	of	ADP
bjp-61292	10	36	breast	breast	NOUN
bjp-61292	10	37	cancer	cancer	NOUN
bjp-61292	10	38	.	.	PUNCT
bjp-61292	11	1	dickkopf	dickkopf	VERB
bjp-61292	11	2	1	1	NUM
bjp-61292	11	3	(	(	PUNCT
bjp-61292	11	4	dkk1	dkk1	PROPN
bjp-61292	11	5	)	)	PUNCT
bjp-61292	11	6	was	be	AUX
bjp-61292	11	7	both	both	PRON
bjp-61292	11	8	expressed	express	VERB
bjp-61292	11	9	in	in	ADP
bjp-61292	11	10	breast	breast	NOUN
bjp-61292	11	11	cancer	cancer	NOUN
bjp-61292	11	12	cells	cell	NOUN
bjp-61292	11	13	and	and	CCONJ
bjp-61292	11	14	exosomes	exosome	NOUN
bjp-61292	11	15	isolated	isolate	VERB
bjp-61292	11	16	from	from	ADP
bjp-61292	11	17	breast	breast	NOUN
bjp-61292	11	18	cancer	cancer	NOUN
bjp-61292	11	19	cells	cell	NOUN
bjp-61292	11	20	.	.	PUNCT
bjp-61292	12	1	the	the	DET
bjp-61292	12	2	expression	expression	NOUN
bjp-61292	12	3	of	of	ADP
bjp-61292	12	4	dkk1	dkk1	PROPN
bjp-61292	12	5	was	be	AUX
bjp-61292	12	6	synchronously	synchronously	ADV
bjp-61292	12	7	inhibited	inhibit	VERB
bjp-61292	12	8	in	in	ADP
bjp-61292	12	9	breast	breast	NOUN
bjp-61292	12	10	cancer	cancer	NOUN
bjp-61292	12	11	cells	cell	NOUN
bjp-61292	12	12	and	and	CCONJ
bjp-61292	12	13	exosomes	exosome	NOUN
bjp-61292	12	14	with	with	ADP
bjp-61292	12	15	zoledronic	zoledronic	ADJ
bjp-61292	12	16	acid	acid	NOUN
bjp-61292	12	17	or	or	CCONJ
bjp-61292	12	18	transfecting	transfecte	VERB
bjp-61292	12	19	with	with	ADP
bjp-61292	12	20	cdna3.1	cdna3.1	PROPN
bjp-61292	12	21	-	-	PROPN
bjp-61292	12	22	dkk1	dkk1	PROPN
bjp-61292	12	23	.	.	PUNCT
bjp-61292	13	1	the	the	DET
bjp-61292	13	2	proliferation	proliferation	NOUN
bjp-61292	13	3	and	and	CCONJ
bjp-61292	13	4	migration	migration	NOUN
bjp-61292	13	5	of	of	ADP
bjp-61292	13	6	mda	mda	PROPN
bjp-61292	13	7	-	-	PUNCT
bjp-61292	13	8	mb-453	mb-453	NOUN
bjp-61292	13	9	cells	cell	NOUN
bjp-61292	13	10	were	be	AUX
bjp-61292	13	11	greatly	greatly	ADV
bjp-61292	13	12	repressed	repress	VERB
bjp-61292	13	13	and	and	CCONJ
bjp-61292	13	14	the	the	DET
bjp-61292	13	15	differentiation	differentiation	NOUN
bjp-61292	13	16	and	and	CCONJ
bjp-61292	13	17	maturity	maturity	NOUN
bjp-61292	13	18	of	of	ADP
bjp-61292	13	19	osteoclasts	osteoclast	NOUN
bjp-61292	13	20	were	be	AUX
bjp-61292	13	21	dramatically	dramatically	ADV
bjp-61292	13	22	repressed	repress	VERB
bjp-61292	13	23	by	by	ADP
bjp-61292	13	24	exosomes	exosome	NOUN
bjp-61292	13	25	derived	derive	VERB
bjp-61292	13	26	from	from	ADP
bjp-61292	13	27	zoledronic	zoledronic	ADJ
bjp-61292	13	28	acid	acid	NOUN
bjp-61292	13	29	-	-	PUNCT
bjp-61292	13	30	treated	treat	VERB
bjp-61292	13	31	mda	mda	PROPN
bjp-61292	13	32	-	-	PUNCT
bjp-61292	13	33	mb-453	mb-453	NUM
bjp-61292	13	34	cells	cell	NOUN
bjp-61292	13	35	.	.	PUNCT
bjp-61292	14	1	in	in	ADP
bjp-61292	14	2	the	the	DET
bjp-61292	14	3	co	co	ADJ
bjp-61292	14	4	-	-	ADJ
bjp-61292	14	5	cultural	cultural	ADJ
bjp-61292	14	6	system	system	NOUN
bjp-61292	14	7	of	of	ADP
bjp-61292	14	8	raw264.7	raw264.7	PROPN
bjp-61292	14	9	cells	cell	NOUN
bjp-61292	14	10	and	and	CCONJ
bjp-61292	14	11	mda	mda	NOUN
bjp-61292	14	12	-	-	PUNCT
bjp-61292	14	13	mb-453	mb-453	NOUN
bjp-61292	14	14	cells	cell	NOUN
bjp-61292	14	15	,	,	PUNCT
bjp-61292	14	16	the	the	DET
bjp-61292	14	17	proliferation	proliferation	NOUN
bjp-61292	14	18	and	and	CCONJ
bjp-61292	14	19	migration	migration	NOUN
bjp-61292	14	20	of	of	ADP
bjp-61292	14	21	mda	mda	PROPN
bjp-61292	14	22	-	-	PUNCT
bjp-61292	14	23	mb-453	mb-453	NOUN
bjp-61292	14	24	cells	cell	NOUN
bjp-61292	14	25	were	be	AUX
bjp-61292	14	26	facilitated	facilitate	VERB
bjp-61292	14	27	by	by	ADP
bjp-61292	14	28	exosomes	exosome	NOUN
bjp-61292	14	29	derived	derive	VERB
bjp-61292	14	30	from	from	ADP
bjp-61292	14	31	mda	mda	PROPN
bjp-61292	14	32	-	-	PUNCT
bjp-61292	14	33	mb-453	mb-453	NUM
bjp-61292	14	34	cells	cell	NOUN
bjp-61292	14	35	.	.	PUNCT
bjp-61292	15	1	lastly	lastly	ADV
bjp-61292	15	2	,	,	PUNCT
bjp-61292	15	3	the	the	DET
bjp-61292	15	4	emt	emt	PROPN
bjp-61292	15	5	progression	progression	NOUN
bjp-61292	15	6	and	and	CCONJ
bjp-61292	15	7	tgf	tgf	PROPN
bjp-61292	15	8	-	-	PUNCT
bjp-61292	15	9	β	β	PROPN
bjp-61292	15	10	signaling	signaling	NOUN
bjp-61292	15	11	were	be	AUX
bjp-61292	15	12	significantly	significantly	ADV
bjp-61292	15	13	blocked	block	VERB
bjp-61292	15	14	by	by	ADP
bjp-61292	15	15	exosomes	exosome	NOUN
bjp-61292	15	16	derived	derive	VERB
bjp-61292	15	17	from	from	ADP
bjp-61292	15	18	zoledronic	zoledronic	ADJ
bjp-61292	15	19	acid	acid	NOUN
bjp-61292	15	20	-	-	PUNCT
bjp-61292	15	21	treated	treat	VERB
bjp-61292	15	22	mda	mda	PROPN
bjp-61292	15	23	-	-	PUNCT
bjp-61292	15	24	mb-453	mb-453	NUM
bjp-61292	15	25	cells	cell	NOUN
bjp-61292	15	26	.	.	PUNCT
bjp-61292	16	1	zoledronic	zoledronic	ADJ
bjp-61292	16	2	acid	acid	PROPN
bjp-61292	16	3	suppressed	suppress	VERB
bjp-61292	16	4	the	the	DET
bjp-61292	16	5	bone	bone	NOUN
bjp-61292	16	6	metastasis	metastasis	NOUN
bjp-61292	16	7	of	of	ADP
bjp-61292	16	8	breast	breast	NOUN
bjp-61292	16	9	cancer	cancer	NOUN
bjp-61292	16	10	by	by	ADP
bjp-61292	16	11	inhibiting	inhibit	VERB
bjp-61292	16	12	the	the	DET
bjp-61292	16	13	exosomes	exosome	NOUN
bjp-61292	16	14	loaded	load	VERB
bjp-61292	16	15	with	with	ADP
bjp-61292	16	16	dkk1	dkk1	PROPN
bjp-61292	16	17	.	.	PUNCT
bjp-61292	17	1	article	article	NOUN
bjp-61292	17	2	info	info	NOUN
bjp-61292	17	3	received	receive	VERB
bjp-61292	17	4	:	:	PUNCT
bjp-61292	17	5	17	17	NUM
bjp-61292	17	6	august	august	PROPN
bjp-61292	17	7	2022	2022	NUM
bjp-61292	17	8	accepted	accept	VERB
bjp-61292	17	9	:	:	PUNCT
bjp-61292	17	10	2	2	NUM
bjp-61292	17	11	september	september	PROPN
bjp-61292	17	12	2022	2022	NUM
bjp-61292	17	13	available	available	ADJ
bjp-61292	17	14	online	online	ADV
bjp-61292	17	15	:	:	PUNCT
bjp-61292	17	16	7	7	NUM
bjp-61292	17	17	september	september	PROPN
bjp-61292	17	18	2022	2022	NUM
bjp-61292	17	19	doi	doi	NOUN
bjp-61292	17	20	:	:	PUNCT
bjp-61292	17	21	10.3329	10.3329	NUM
bjp-61292	17	22	/	/	SYM
bjp-61292	17	23	bjp.v17i3.61292	bjp.v17i3.61292	PROPN
bjp-61292	17	24	cite	cite	VERB
bjp-61292	17	25	this	this	DET
bjp-61292	17	26	article	article	NOUN
bjp-61292	17	27	:	:	PUNCT
bjp-61292	17	28	song	song	PROPN
bjp-61292	17	29	bb	bb	PROPN
bjp-61292	17	30	,	,	PUNCT
bjp-61292	17	31	xu	xu	PROPN
bjp-61292	18	1	my	my	PRON
bjp-61292	18	2	,	,	PUNCT
bjp-61292	18	3	xu	xu	PROPN
bjp-61292	18	4	xf	xf	PROPN
bjp-61292	18	5	,	,	PUNCT
bjp-61292	18	6	li	li	PROPN
bjp-61292	18	7	x	x	PROPN
bjp-61292	18	8	,	,	PUNCT
bjp-61292	18	9	chen	chen	PROPN
bjp-61292	18	10	m.	m.	PROPN
bjp-61292	18	11	zoledronic	zoledronic	PROPN
bjp-61292	18	12	acid	acid	PROPN
bjp-61292	18	13	inhibits	inhibit	VERB
bjp-61292	18	14	the	the	DET
bjp-61292	18	15	bone	bone	NOUN
bjp-61292	18	16	metastasis	metastasis	NOUN
bjp-61292	18	17	of	of	ADP
bjp-61292	18	18	breast	breast	NOUN
bjp-61292	18	19	cancer	cancer	NOUN
bjp-61292	18	20	by	by	ADP
bjp-61292	18	21	repressi	repressi	PROPN
bjp-61292	18	22	n	n	CCONJ
bjp-61292	18	23	g	g	NOUN
bjp-61292	18	24	e	e	NOUN
bjp-61292	18	25	x	x	PUNCT
bjp-61292	19	1	o	o	NOUN
bjp-61292	19	2	s	s	X
bjp-61292	19	3	o	o	NOUN
bjp-61292	19	4	m	m	NOUN
bjp-61292	19	5	e	e	X
bjp-61292	19	6	l	l	NOUN
bjp-61292	19	7	o	o	X
bjp-61292	19	8	a	a	X
bjp-61292	19	9	d	d	X
bjp-61292	19	10	e	e	X
bjp-61292	19	11	d	d	PROPN
bjp-61292	19	12	d	d	X
bjp-61292	19	13	k	k	PROPN
bjp-61292	19	14	k	k	PROPN
bjp-61292	19	15	1	1	X
bjp-61292	19	16	.	.	PUNCT
bjp-61292	20	1	bangladesh	bangladesh	PROPN
bjp-61292	20	2	j	j	PROPN
bjp-61292	20	3	pharmacol	pharmacol	PROPN
bjp-61292	20	4	.	.	PUNCT
bjp-61292	20	5	2022	2022	NUM
bjp-61292	20	6	;	;	PUNCT
bjp-61292	20	7	17	17	NUM
bjp-61292	20	8	:	:	SYM
bjp-61292	20	9	92101	92101	NUM
bjp-61292	20	10	.	.	PUNCT
bjp-61292	21	1	zoledronic	zoledronic	ADJ
bjp-61292	21	2	acid	acid	PROPN
bjp-61292	21	3	inhibits	inhibit	VERB
bjp-61292	21	4	the	the	DET
bjp-61292	21	5	bone	bone	NOUN
bjp-61292	21	6	metastasis	metastasis	NOUN
bjp-61292	21	7	of	of	ADP
bjp-61292	21	8	breast	breast	NOUN
bjp-61292	21	9	cancer	cancer	NOUN
bjp-61292	21	10	by	by	ADP
bjp-61292	21	11	repressing	repress	VERB
bjp-61292	21	12	exosome	exosome	NOUN
bjp-61292	21	13	-	-	PUNCT
bjp-61292	21	14	loaded	load	VERB
bjp-61292	21	15	dkk1	dkk1	PROPN
bjp-61292	21	16	bin	bin	PROPN
bjp-61292	21	17	bin	bin	PROPN
bjp-61292	21	18	song1	song1	PROPN
bjp-61292	21	19	,	,	PUNCT
bjp-61292	21	20	mao	mao	NOUN
bjp-61292	22	1	yi	yi	PROPN
bjp-61292	23	1	xu2	xu2	PROPN
bjp-61292	23	2	,	,	PUNCT
bjp-61292	23	3	xiao	xiao	PROPN
bjp-61292	23	4	fang	fang	PROPN
bjp-61292	23	5	xu2	xu2	PROPN
bjp-61292	23	6	,	,	PUNCT
bjp-61292	23	7	xia	xia	PROPN
bjp-61292	23	8	li2	li2	PROPN
bjp-61292	23	9	,	,	PUNCT
bjp-61292	23	10	and	and	CCONJ
bjp-61292	23	11	ming	ming	PROPN
bjp-61292	23	12	chen1	chen1	PROPN
bjp-61292	23	13	1	1	NUM
bjp-61292	23	14	department	department	NOUN
bjp-61292	23	15	of	of	ADP
bjp-61292	23	16	radiotherapy	radiotherapy	NOUN
bjp-61292	23	17	,	,	PUNCT
bjp-61292	23	18	the	the	DET
bjp-61292	23	19	second	second	ADJ
bjp-61292	23	20	affiliated	affiliated	ADJ
bjp-61292	23	21	hospital	hospital	NOUN
bjp-61292	23	22	of	of	ADP
bjp-61292	23	23	soochow	soochow	PROPN
bjp-61292	23	24	university	university	PROPN
bjp-61292	23	25	,	,	PUNCT
bjp-61292	23	26	suzhou	suzhou	PROPN
bjp-61292	23	27	215004	215004	NUM
bjp-61292	23	28	,	,	PUNCT
bjp-61292	23	29	jiangsu	jiangsu	PROPN
bjp-61292	23	30	,	,	PUNCT
bjp-61292	23	31	china	china	PROPN
bjp-61292	23	32	;	;	PUNCT
bjp-61292	23	33	2	2	NUM
bjp-61292	23	34	department	department	NOUN
bjp-61292	23	35	of	of	ADP
bjp-61292	23	36	medical	medical	ADJ
bjp-61292	23	37	oncology	oncology	NOUN
bjp-61292	23	38	,	,	PUNCT
bjp-61292	23	39	the	the	DET
bjp-61292	23	40	affiliated	affiliated	ADJ
bjp-61292	23	41	hospital	hospital	NOUN
bjp-61292	23	42	of	of	ADP
bjp-61292	23	43	jiaxing	jiaxing	PROPN
bjp-61292	23	44	university	university	PROPN
bjp-61292	23	45	,	,	PUNCT
bjp-61292	23	46	jiaxing	jiaxing	PROPN
bjp-61292	23	47	310012	310012	NUM
bjp-61292	23	48	,	,	PUNCT
bjp-61292	23	49	zhejiang	zhejiang	PROPN
bjp-61292	23	50	,	,	PUNCT
bjp-61292	23	51	china	china	PROPN
bjp-61292	23	52	.	.	PUNCT
bjp-61292	24	1	this	this	DET
bjp-61292	24	2	work	work	NOUN
bjp-61292	24	3	is	be	AUX
bjp-61292	24	4	licensed	license	VERB
bjp-61292	24	5	under	under	ADP
bjp-61292	24	6	a	a	DET
bjp-61292	24	7	creative	creative	ADJ
bjp-61292	24	8	commons	common	NOUN
bjp-61292	24	9	attribution	attribution	NOUN
bjp-61292	24	10	4.0	4.0	NUM
bjp-61292	24	11	license	license	NOUN
bjp-61292	24	12	.	.	PUNCT
bjp-61292	25	1	you	you	PRON
bjp-61292	25	2	are	be	AUX
bjp-61292	25	3	free	free	ADJ
bjp-61292	25	4	to	to	PART
bjp-61292	25	5	copy	copy	VERB
bjp-61292	25	6	,	,	PUNCT
bjp-61292	25	7	distribute	distribute	VERB
bjp-61292	25	8	and	and	CCONJ
bjp-61292	25	9	perform	perform	VERB
bjp-61292	25	10	the	the	DET
bjp-61292	25	11	work	work	NOUN
bjp-61292	25	12	.	.	PUNCT
bjp-61292	26	1	you	you	PRON
bjp-61292	26	2	must	must	AUX
bjp-61292	26	3	attribute	attribute	VERB
bjp-61292	26	4	the	the	DET
bjp-61292	26	5	work	work	NOUN
bjp-61292	26	6	in	in	ADP
bjp-61292	26	7	the	the	DET
bjp-61292	26	8	manner	manner	NOUN
bjp-61292	26	9	specified	specify	VERB
bjp-61292	26	10	by	by	ADP
bjp-61292	26	11	the	the	DET
bjp-61292	26	12	author	author	NOUN
bjp-61292	26	13	or	or	CCONJ
bjp-61292	26	14	licensor	licensor	NOUN
bjp-61292	26	15	.	.	PUNCT
bjp-61292	27	1	a	a	DET
bjp-61292	27	2	journal	journal	NOUN
bjp-61292	27	3	of	of	ADP
bjp-61292	27	4	the	the	DET
bjp-61292	27	5	bangladesh	bangladesh	NOUN
bjp-61292	27	6	pharmacological	pharmacological	ADJ
bjp-61292	27	7	society	society	NOUN
bjp-61292	27	8	(	(	PUNCT
bjp-61292	27	9	bdps	bdps	NOUN
bjp-61292	27	10	)	)	PUNCT
bjp-61292	27	11	bangladesh	bangladesh	PROPN
bjp-61292	27	12	j	j	PROPN
bjp-61292	27	13	pharmacol	pharmacol	PROPN
bjp-61292	27	14	2022	2022	NUM
bjp-61292	27	15	;	;	PUNCT
bjp-61292	27	16	17	17	NUM
bjp-61292	27	17	:	:	SYM
bjp-61292	27	18	92	92	NUM
bjp-61292	27	19	-	-	SYM
bjp-61292	27	20	101	101	NUM
bjp-61292	27	21	journal	journal	NOUN
bjp-61292	27	22	homepage	homepage	NOUN
bjp-61292	27	23	:	:	PUNCT
bjp-61292	27	24	www.banglajol.info	www.banglajol.info	PROPN
bjp-61292	27	25	;	;	PUNCT
bjp-61292	27	26	www.bdpsjournal.org	www.bdpsjournal.org	NUM
bjp-61292	27	27	abstracted	abstract	VERB
bjp-61292	27	28	/	/	SYM
bjp-61292	27	29	indexed	index	VERB
bjp-61292	27	30	in	in	ADP
bjp-61292	27	31	academic	academic	ADJ
bjp-61292	27	32	search	search	NOUN
bjp-61292	27	33	complete	complete	ADJ
bjp-61292	27	34	,	,	PUNCT
bjp-61292	27	35	agroforestry	agroforestry	NOUN
bjp-61292	27	36	abstracts	abstract	NOUN
bjp-61292	27	37	,	,	PUNCT
bjp-61292	27	38	asia	asia	PROPN
bjp-61292	27	39	journals	journal	NOUN
bjp-61292	27	40	online	online	ADV
bjp-61292	27	41	,	,	PUNCT
bjp-61292	27	42	bangladesh	bangladesh	NOUN
bjp-61292	27	43	journals	journal	NOUN
bjp-61292	27	44	online	online	ADV
bjp-61292	27	45	,	,	PUNCT
bjp-61292	27	46	biological	biological	ADJ
bjp-61292	27	47	abstracts	abstract	NOUN
bjp-61292	27	48	,	,	PUNCT
bjp-61292	27	49	biosis	biosis	NOUN
bjp-61292	27	50	previews	preview	NOUN
bjp-61292	27	51	,	,	PUNCT
bjp-61292	27	52	cab	cab	NOUN
bjp-61292	27	53	abstracts	abstract	NOUN
bjp-61292	27	54	,	,	PUNCT
bjp-61292	27	55	current	current	ADJ
bjp-61292	27	56	abstracts	abstract	NOUN
bjp-61292	27	57	,	,	PUNCT
bjp-61292	27	58	directory	directory	NOUN
bjp-61292	27	59	of	of	ADP
bjp-61292	27	60	open	open	ADJ
bjp-61292	27	61	access	access	NOUN
bjp-61292	27	62	journals	journal	NOUN
bjp-61292	27	63	,	,	PUNCT
bjp-61292	27	64	embase	embase	NOUN
bjp-61292	27	65	/	/	SYM
bjp-61292	27	66	excerpta	excerpta	NOUN
bjp-61292	27	67	medica	medica	NOUN
bjp-61292	27	68	,	,	PUNCT
bjp-61292	27	69	global	global	ADJ
bjp-61292	27	70	health	health	NOUN
bjp-61292	27	71	,	,	PUNCT
bjp-61292	27	72	google	google	PROPN
bjp-61292	27	73	scholar	scholar	NOUN
bjp-61292	27	74	,	,	PUNCT
bjp-61292	27	75	hinari	hinari	X
bjp-61292	27	76	(	(	PUNCT
bjp-61292	27	77	who	who	PRON
bjp-61292	27	78	)	)	PUNCT
bjp-61292	27	79	,	,	PUNCT
bjp-61292	27	80	international	international	ADJ
bjp-61292	27	81	pharmaceutical	pharmaceutical	ADJ
bjp-61292	27	82	abstracts	abstract	NOUN
bjp-61292	27	83	,	,	PUNCT
bjp-61292	27	84	open	open	ADJ
bjp-61292	27	85	j	j	PROPN
bjp-61292	27	86	-	-	PUNCT
bjp-61292	27	87	gate	gate	NOUN
bjp-61292	27	88	,	,	PUNCT
bjp-61292	27	89	science	science	NOUN
bjp-61292	27	90	citation	citation	NOUN
bjp-61292	27	91	index	index	NOUN
bjp-61292	27	92	expanded	expand	VERB
bjp-61292	27	93	,	,	PUNCT
bjp-61292	27	94	scopus	scopus	NOUN
bjp-61292	27	95	and	and	CCONJ
bjp-61292	27	96	social	social	ADJ
bjp-61292	27	97	sciences	sciences	PROPN
bjp-61292	27	98	citation	citation	NOUN
bjp-61292	27	99	index	index	NOUN
bjp-61292	27	100	issn	issn	PROPN
bjp-61292	27	101	:	:	PUNCT
bjp-61292	27	102	1991	1991	NUM
bjp-61292	27	103	-	-	SYM
bjp-61292	27	104	0088	0088	NUM
bjp-61292	27	105	microenvironment	microenvironment	NOUN
bjp-61292	27	106	.	.	PUNCT
bjp-61292	28	1	disseminated	disseminate	VERB
bjp-61292	28	2	tumor	tumor	NOUN
bjp-61292	28	3	cells	cell	NOUN
bjp-61292	28	4	(	(	PUNCT
bjp-61292	28	5	dtcs	dtcs	NOUN
bjp-61292	28	6	)	)	PUNCT
bjp-61292	28	7	induce	induce	VERB
bjp-61292	28	8	the	the	DET
bjp-61292	28	9	formation	formation	NOUN
bjp-61292	28	10	of	of	ADP
bjp-61292	28	11	metastatic	metastatic	ADJ
bjp-61292	28	12	niche	niche	NOUN
bjp-61292	28	13	in	in	ADP
bjp-61292	28	14	the	the	DET
bjp-61292	28	15	bone	bone	NOUN
bjp-61292	28	16	microenvironment	microenvironment	NOUN
bjp-61292	28	17	by	by	ADP
bjp-61292	28	18	secreting	secrete	VERB
bjp-61292	28	19	such	such	ADJ
bjp-61292	28	20	cytokines	cytokine	NOUN
bjp-61292	28	21	as	as	ADP
bjp-61292	28	22	parathyroid	parathyroid	ADJ
bjp-61292	28	23	hormone	hormone	NOUN
bjp-61292	28	24	-	-	PUNCT
bjp-61292	28	25	related	relate	VERB
bjp-61292	28	26	protein	protein	NOUN
bjp-61292	28	27	(	(	PUNCT
bjp-61292	28	28	pthrp	pthrp	NOUN
bjp-61292	28	29	)	)	PUNCT
bjp-61292	28	30	,	,	PUNCT
bjp-61292	28	31	heparanase	heparanase	NOUN
bjp-61292	28	32	(	(	PUNCT
bjp-61292	28	33	hpse	hpse	NOUN
bjp-61292	28	34	)	)	PUNCT
bjp-61292	28	35	,	,	PUNCT
bjp-61292	28	36	and	and	CCONJ
bjp-61292	28	37	osteopontin	osteopontin	PROPN
bjp-61292	28	38	(	(	PUNCT
bjp-61292	28	39	opn	opn	PROPN
bjp-61292	28	40	)	)	PUNCT
bjp-61292	28	41	,	,	PUNCT
bjp-61292	28	42	which	which	PRON
bjp-61292	28	43	further	far	ADV
bjp-61292	28	44	facilitates	facilitate	VERB
bjp-61292	28	45	the	the	DET
bjp-61292	28	46	planting	planting	NOUN
bjp-61292	28	47	of	of	ADP
bjp-61292	28	48	tumor	tumor	NOUN
bjp-61292	28	49	cells	cell	NOUN
bjp-61292	28	50	in	in	ADP
bjp-61292	28	51	the	the	DET
bjp-61292	28	52	bone	bone	NOUN
bjp-61292	28	53	microenvironment	microenvironment	NOUN
bjp-61292	28	54	(	(	PUNCT
bjp-61292	28	55	ell	ell	INTJ
bjp-61292	28	56	and	and	CCONJ
bjp-61292	28	57	kang	kang	PROPN
bjp-61292	28	58	,	,	PUNCT
bjp-61292	28	59	2012	2012	NUM
bjp-61292	28	60	)	)	PUNCT
bjp-61292	28	61	.	.	PUNCT
bjp-61292	29	1	planted	plant	VERB
bjp-61292	29	2	tumor	tumor	NOUN
bjp-61292	29	3	cells	cell	NOUN
bjp-61292	29	4	recruit	recruit	VERB
bjp-61292	29	5	osteoclasts	osteoclast	NOUN
bjp-61292	29	6	and	and	CCONJ
bjp-61292	29	7	induce	induce	VERB
bjp-61292	29	8	the	the	DET
bjp-61292	29	9	overactivation	overactivation	NOUN
bjp-61292	29	10	and	and	CCONJ
bjp-61292	29	11	mature	mature	NOUN
bjp-61292	29	12	of	of	ADP
bjp-61292	29	13	osteoclasts	osteoclast	NOUN
bjp-61292	29	14	by	by	ADP
bjp-61292	29	15	interacting	interact	VERB
bjp-61292	29	16	with	with	ADP
bjp-61292	29	17	osteoblasts	osteoblast	NOUN
bjp-61292	29	18	and	and	CCONJ
bjp-61292	29	19	osteoclasts	osteoclast	NOUN
bjp-61292	29	20	,	,	PUNCT
bjp-61292	29	21	which	which	PRON
bjp-61292	29	22	further	far	ADV
bjp-61292	29	23	induces	induce	VERB
bjp-61292	29	24	the	the	DET
bjp-61292	29	25	serious	serious	ADJ
bjp-61292	29	26	reaction	reaction	NOUN
bjp-61292	29	27	of	of	ADP
bjp-61292	29	28	osteolysis	osteolysis	ADJ
bjp-61292	29	29	destruction	destruction	NOUN
bjp-61292	29	30	on	on	ADP
bjp-61292	29	31	the	the	DET
bjp-61292	29	32	interface	interface	NOUN
bjp-61292	29	33	between	between	ADP
bjp-61292	29	34	bone	bone	NOUN
bjp-61292	29	35	tissues	tissue	NOUN
bjp-61292	29	36	and	and	CCONJ
bjp-61292	29	37	tumor	tumor	NOUN
bjp-61292	29	38	tissues	tissue	NOUN
bjp-61292	29	39	.	.	PUNCT
bjp-61292	30	1	the	the	DET
bjp-61292	30	2	growth	growth	NOUN
bjp-61292	30	3	factors	factor	NOUN
bjp-61292	30	4	located	locate	VERB
bjp-61292	30	5	in	in	ADP
bjp-61292	30	6	bone	bone	NOUN
bjp-61292	30	7	tissues	tissue	NOUN
bjp-61292	30	8	are	be	AUX
bjp-61292	30	9	triggered	trigger	VERB
bjp-61292	30	10	to	to	PART
bjp-61292	30	11	be	be	AUX
bjp-61292	30	12	released	release	VERB
bjp-61292	30	13	into	into	ADP
bjp-61292	30	14	the	the	DET
bjp-61292	30	15	bone	bone	NOUN
bjp-61292	30	16	microenvironment	microenvironment	NOUN
bjp-61292	30	17	,	,	PUNCT
bjp-61292	30	18	which	which	PRON
bjp-61292	30	19	further	far	ADV
bjp-61292	30	20	facilitates	facilitate	VERB
bjp-61292	30	21	the	the	DET
bjp-61292	30	22	proliferation	proliferation	NOUN
bjp-61292	30	23	of	of	ADP
bjp-61292	30	24	tumor	tumor	NOUN
bjp-61292	30	25	cells	cell	NOUN
bjp-61292	30	26	(	(	PUNCT
bjp-61292	30	27	weilbaecher	weilbaecher	NOUN
bjp-61292	30	28	et	et	PROPN
bjp-61292	30	29	al	al	PROPN
bjp-61292	30	30	.	.	PROPN
bjp-61292	30	31	,	,	PUNCT
bjp-61292	30	32	2011	2011	NUM
bjp-61292	30	33	)	)	PUNCT
bjp-61292	30	34	.	.	PUNCT
bjp-61292	31	1	exosomes	exosome	NOUN
bjp-61292	31	2	are	be	AUX
bjp-61292	31	3	a	a	DET
bjp-61292	31	4	group	group	NOUN
bjp-61292	31	5	of	of	ADP
bjp-61292	31	6	30	30	NUM
bjp-61292	31	7	-	-	SYM
bjp-61292	31	8	100	100	NUM
bjp-61292	31	9	nm	nm	ADJ
bjp-61292	31	10	extracellular	extracellular	ADJ
bjp-61292	31	11	vesicles	vesicle	NOUN
bjp-61292	31	12	generated	generate	VERB
bjp-61292	31	13	from	from	ADP
bjp-61292	31	14	endocytosis	endocytosis	NOUN
bjp-61292	31	15	(	(	PUNCT
bjp-61292	31	16	kahlert	kahlert	PROPN
bjp-61292	31	17	and	and	CCONJ
bjp-61292	31	18	kalluri	kalluri	PROPN
bjp-61292	31	19	,	,	PUNCT
bjp-61292	31	20	2013	2013	NUM
bjp-61292	31	21	)	)	PUNCT
bjp-61292	31	22	,	,	PUNCT
bjp-61292	31	23	which	which	PRON
bjp-61292	31	24	mediate	mediate	VERB
bjp-61292	31	25	the	the	DET
bjp-61292	31	26	communication	communication	NOUN
bjp-61292	31	27	among	among	ADP
bjp-61292	31	28	cells	cell	NOUN
bjp-61292	31	29	by	by	ADP
bjp-61292	31	30	delivering	deliver	VERB
bjp-61292	31	31	signals	signal	NOUN
bjp-61292	31	32	through	through	ADP
bjp-61292	31	33	releasing	release	VERB
bjp-61292	31	34	multiple	multiple	ADJ
bjp-61292	31	35	types	type	NOUN
bjp-61292	31	36	of	of	ADP
bjp-61292	31	37	biomolecules	biomolecule	NOUN
bjp-61292	31	38	,	,	PUNCT
bjp-61292	31	39	such	such	ADJ
bjp-61292	31	40	as	as	ADP
bjp-61292	31	41	nucleic	nucleic	ADJ
bjp-61292	31	42	acids	acid	NOUN
bjp-61292	31	43	and	and	CCONJ
bjp-61292	31	44	proteins	protein	NOUN
bjp-61292	31	45	,	,	PUNCT
bjp-61292	31	46	into	into	ADP
bjp-61292	31	47	the	the	DET
bjp-61292	31	48	recipient	recipient	NOUN
bjp-61292	31	49	cells	cell	NOUN
bjp-61292	31	50	(	(	PUNCT
bjp-61292	31	51	zhang	zhang	X
bjp-61292	31	52	et	et	PROPN
bjp-61292	31	53	al	al	PROPN
bjp-61292	31	54	.	.	PROPN
bjp-61292	31	55	,	,	PUNCT
bjp-61292	31	56	2015	2015	NUM
bjp-61292	31	57	)	)	PUNCT
bjp-61292	31	58	.	.	PUNCT
bjp-61292	32	1	it	it	PRON
bjp-61292	32	2	is	be	AUX
bjp-61292	32	3	reported	report	VERB
bjp-61292	32	4	that	that	SCONJ
bjp-61292	32	5	tumor	tumor	NOUN
bjp-61292	32	6	cell	cell	NOUN
bjp-61292	32	7	-	-	PUNCT
bjp-61292	32	8	derived	derive	VERB
bjp-61292	32	9	exosomes	exosome	NOUN
bjp-61292	32	10	contribute	contribute	VERB
bjp-61292	32	11	to	to	ADP
bjp-61292	32	12	the	the	DET
bjp-61292	32	13	growth	growth	NOUN
bjp-61292	32	14	and	and	CCONJ
bjp-61292	32	15	proliferation	proliferation	NOUN
bjp-61292	32	16	of	of	ADP
bjp-61292	32	17	tumor	tumor	NOUN
bjp-61292	32	18	cells	cell	NOUN
bjp-61292	32	19	by	by	ADP
bjp-61292	32	20	releasing	release	VERB
bjp-61292	32	21	oncogenic	oncogenic	ADJ
bjp-61292	32	22	mirnas	mirna	NOUN
bjp-61292	32	23	(	(	PUNCT
bjp-61292	32	24	rabinowits	rabinowit	NOUN
bjp-61292	32	25	et	et	PROPN
bjp-61292	32	26	al	al	PROPN
bjp-61292	32	27	.	.	PROPN
bjp-61292	32	28	,	,	PUNCT
bjp-61292	32	29	2009	2009	NUM
bjp-61292	32	30	;	;	PUNCT
bjp-61292	32	31	bryant	bryant	PROPN
bjp-61292	32	32	et	et	PROPN
bjp-61292	32	33	al	al	PROPN
bjp-61292	32	34	.	.	PROPN
bjp-61292	32	35	,	,	PUNCT
bjp-61292	32	36	2012	2012	NUM
bjp-61292	32	37	)	)	PUNCT
bjp-61292	32	38	.	.	PUNCT
bjp-61292	33	1	recently	recently	ADV
bjp-61292	33	2	,	,	PUNCT
bjp-61292	33	3	researchers	researcher	NOUN
bjp-61292	33	4	propose	propose	VERB
bjp-61292	33	5	that	that	SCONJ
bjp-61292	33	6	bone	bone	NOUN
bjp-61292	33	7	microenvironment	microenvironment	NOUN
bjp-61292	33	8	can	can	AUX
bjp-61292	33	9	be	be	AUX
bjp-61292	33	10	regulated	regulate	VERB
bjp-61292	33	11	by	by	ADP
bjp-61292	33	12	tumor	tumor	NOUN
bjp-61292	33	13	cell	cell	NOUN
bjp-61292	33	14	-	-	PUNCT
bjp-61292	33	15	derived	derive	VERB
bjp-61292	33	16	exosomes	exosome	NOUN
bjp-61292	33	17	to	to	PART
bjp-61292	33	18	facilitate	facilitate	VERB
bjp-61292	33	19	the	the	DET
bjp-61292	33	20	bone	bone	NOUN
bjp-61292	33	21	metastasis	metastasis	NOUN
bjp-61292	33	22	of	of	ADP
bjp-61292	33	23	tumor	tumor	NOUN
bjp-61292	33	24	cells	cell	NOUN
bjp-61292	33	25	(	(	PUNCT
bjp-61292	33	26	chiconbosch	chiconbosch	ADJ
bjp-61292	33	27	and	and	CCONJ
bjp-61292	33	28	tirado	tirado	NOUN
bjp-61292	33	29	,	,	PUNCT
bjp-61292	33	30	2020	2020	NUM
bjp-61292	33	31	;	;	PUNCT
bjp-61292	33	32	yuan	yuan	NOUN
bjp-61292	33	33	et	et	PROPN
bjp-61292	33	34	al	al	PROPN
bjp-61292	33	35	.	.	PROPN
bjp-61292	33	36	,	,	PUNCT
bjp-61292	33	37	2021	2021	NUM
bjp-61292	33	38	)	)	PUNCT
bjp-61292	33	39	.	.	PUNCT
bjp-61292	34	1	bone	bone	NOUN
bjp-61292	34	2	-	-	PUNCT
bjp-61292	34	3	modifying	modify	VERB
bjp-61292	34	4	agents	agent	NOUN
bjp-61292	34	5	therapy	therapy	NOUN
bjp-61292	34	6	was	be	AUX
bjp-61292	34	7	one	one	NUM
bjp-61292	34	8	of	of	ADP
bjp-61292	34	9	the	the	DET
bjp-61292	34	10	treatment	treatment	NOUN
bjp-61292	34	11	options	option	NOUN
bjp-61292	34	12	for	for	ADP
bjp-61292	34	13	bone	bone	NOUN
bjp-61292	34	14	metastasis	metastasis	NOUN
bjp-61292	34	15	.	.	PUNCT
bjp-61292	35	1	of	of	ADP
bjp-61292	35	2	the	the	DET
bjp-61292	35	3	medications	medication	NOUN
bjp-61292	35	4	for	for	ADP
bjp-61292	35	5	bone	bone	NOUN
bjp-61292	35	6	metastases	metastasis	NOUN
bjp-61292	35	7	,	,	PUNCT
bjp-61292	35	8	bisphosphonates	bisphosphonate	NOUN
bjp-61292	35	9	were	be	AUX
bjp-61292	35	10	used	use	VERB
bjp-61292	35	11	to	to	PART
bjp-61292	35	12	treat	treat	VERB
bjp-61292	35	13	bone	bone	NOUN
bjp-61292	35	14	metastasis	metastasis	NOUN
bjp-61292	35	15	,	,	PUNCT
bjp-61292	35	16	which	which	PRON
bjp-61292	35	17	could	could	AUX
bjp-61292	35	18	help	help	VERB
bjp-61292	35	19	to	to	PART
bjp-61292	35	20	suppress	suppress	VERB
bjp-61292	35	21	the	the	DET
bjp-61292	35	22	breakdown	breakdown	NOUN
bjp-61292	35	23	of	of	ADP
bjp-61292	35	24	bone	bone	NOUN
bjp-61292	35	25	and	and	CCONJ
bjp-61292	35	26	improve	improve	VERB
bjp-61292	35	27	bone	bone	NOUN
bjp-61292	35	28	density	density	NOUN
bjp-61292	35	29	(	(	PUNCT
bjp-61292	35	30	krempien	krempien	VERB
bjp-61292	35	31	et	et	PROPN
bjp-61292	35	32	al	al	PROPN
bjp-61292	35	33	.	.	PROPN
bjp-61292	35	34	,	,	PUNCT
bjp-61292	35	35	2005	2005	NUM
bjp-61292	35	36	)	)	PUNCT
bjp-61292	35	37	.	.	PUNCT
bjp-61292	36	1	bisphosphonates	bisphosphonate	NOUN
bjp-61292	36	2	treatment	treatment	NOUN
bjp-61292	36	3	might	might	AUX
bjp-61292	36	4	be	be	AUX
bjp-61292	36	5	the	the	DET
bjp-61292	36	6	pros	pro	NOUN
bjp-61292	36	7	outweigh	outweigh	VERB
bjp-61292	36	8	the	the	DET
bjp-61292	36	9	cons	con	NOUN
bjp-61292	36	10	among	among	ADP
bjp-61292	36	11	breast	breast	NOUN
bjp-61292	36	12	cancer	cancer	NOUN
bjp-61292	36	13	patients	patient	NOUN
bjp-61292	36	14	with	with	ADP
bjp-61292	36	15	metastatic	metastatic	ADJ
bjp-61292	36	16	disease	disease	NOUN
bjp-61292	36	17	(	(	PUNCT
bjp-61292	36	18	goldvaser	goldvaser	NOUN
bjp-61292	36	19	et	et	PROPN
bjp-61292	36	20	al	al	PROPN
bjp-61292	36	21	.	.	PROPN
bjp-61292	36	22	,	,	PUNCT
bjp-61292	36	23	2019	2019	NUM
bjp-61292	36	24	)	)	PUNCT
bjp-61292	36	25	.	.	PUNCT
bjp-61292	37	1	zoledronic	zoledronic	ADJ
bjp-61292	37	2	acid	acid	PROPN
bjp-61292	37	3	is	be	AUX
bjp-61292	37	4	the	the	DET
bjp-61292	37	5	third	third	ADJ
bjp-61292	37	6	generation	generation	NOUN
bjp-61292	37	7	of	of	ADP
bjp-61292	37	8	bisphosphonates	bisphosphonate	NOUN
bjp-61292	37	9	and	and	CCONJ
bjp-61292	37	10	is	be	AUX
bjp-61292	37	11	mainly	mainly	ADV
bjp-61292	37	12	used	use	VERB
bjp-61292	37	13	for	for	ADP
bjp-61292	37	14	the	the	DET
bjp-61292	37	15	treatment	treatment	NOUN
bjp-61292	37	16	of	of	ADP
bjp-61292	37	17	oncological	oncological	ADJ
bjp-61292	37	18	bone	bone	NOUN
bjp-61292	37	19	metastasis	metastasis	NOUN
bjp-61292	37	20	and	and	CCONJ
bjp-61292	37	21	anti	anti	ADJ
bjp-61292	37	22	-	-	ADJ
bjp-61292	37	23	metabolic	metabolic	ADJ
bjp-61292	37	24	bone	bone	NOUN
bjp-61292	37	25	disease	disease	NOUN
bjp-61292	37	26	.	.	PUNCT
bjp-61292	38	1	however	however	ADV
bjp-61292	38	2	,	,	PUNCT
bjp-61292	38	3	the	the	DET
bjp-61292	38	4	underlying	underlying	ADJ
bjp-61292	38	5	mechanism	mechanism	NOUN
bjp-61292	38	6	for	for	ADP
bjp-61292	38	7	the	the	DET
bjp-61292	38	8	therapeutic	therapeutic	ADJ
bjp-61292	38	9	effects	effect	NOUN
bjp-61292	38	10	of	of	ADP
bjp-61292	38	11	zoledronic	zoledronic	ADJ
bjp-61292	38	12	acid	acid	NOUN
bjp-61292	38	13	against	against	ADP
bjp-61292	38	14	bone	bone	NOUN
bjp-61292	38	15	metastasis	metastasis	NOUN
bjp-61292	38	16	remains	remain	VERB
bjp-61292	38	17	unknown	unknown	ADJ
bjp-61292	38	18	.	.	PUNCT
bjp-61292	39	1	the	the	DET
bjp-61292	39	2	present	present	ADJ
bjp-61292	39	3	study	study	NOUN
bjp-61292	39	4	aims	aim	VERB
bjp-61292	39	5	to	to	PART
bjp-61292	39	6	explore	explore	VERB
bjp-61292	39	7	the	the	DET
bjp-61292	39	8	potential	potential	ADJ
bjp-61292	39	9	mechanism	mechanism	NOUN
bjp-61292	39	10	of	of	ADP
bjp-61292	39	11	zoledronic	zoledronic	ADJ
bjp-61292	39	12	acid	acid	NOUN
bjp-61292	39	13	against	against	ADP
bjp-61292	39	14	bone	bone	NOUN
bjp-61292	39	15	metastasis	metastasis	NOUN
bjp-61292	39	16	in	in	ADP
bjp-61292	39	17	breast	breast	NOUN
bjp-61292	39	18	cancer	cancer	NOUN
bjp-61292	39	19	by	by	ADP
bjp-61292	39	20	investigating	investigate	VERB
bjp-61292	39	21	the	the	DET
bjp-61292	39	22	effects	effect	NOUN
bjp-61292	39	23	of	of	ADP
bjp-61292	39	24	zoledronic	zoledronic	ADJ
bjp-61292	39	25	acid	acid	NOUN
bjp-61292	39	26	on	on	ADP
bjp-61292	39	27	the	the	DET
bjp-61292	39	28	exosomes	exosome	NOUN
bjp-61292	39	29	extracted	extract	VERB
bjp-61292	39	30	from	from	ADP
bjp-61292	39	31	breast	breast	NOUN
bjp-61292	39	32	cancer	cancer	NOUN
bjp-61292	39	33	cells	cell	NOUN
bjp-61292	39	34	.	.	PUNCT
bjp-61292	40	1	materials	material	NOUN
bjp-61292	40	2	and	and	CCONJ
bjp-61292	40	3	methods	method	NOUN
bjp-61292	40	4	cell	cell	NOUN
bjp-61292	40	5	lines	line	NOUN
bjp-61292	40	6	,	,	PUNCT
bjp-61292	40	7	reagents	reagent	NOUN
bjp-61292	40	8	,	,	PUNCT
bjp-61292	40	9	and	and	CCONJ
bjp-61292	40	10	transfection	transfection	NOUN
bjp-61292	40	11	breast	breast	NOUN
bjp-61292	40	12	cancer	cancer	NOUN
bjp-61292	40	13	cells	cell	NOUN
bjp-61292	40	14	(	(	PUNCT
bjp-61292	40	15	mda	mda	NOUN
bjp-61292	40	16	-	-	PUNCT
bjp-61292	40	17	mb-453	mb-453	PROPN
bjp-61292	40	18	and	and	CCONJ
bjp-61292	40	19	mda	mda	PROPN
bjp-61292	40	20	-	-	PUNCT
bjp-61292	40	21	mb-231	mb-231	PROPN
bjp-61292	40	22	)	)	PUNCT
bjp-61292	40	23	and	and	CCONJ
bjp-61292	40	24	mouse	mouse	VERB
bjp-61292	40	25	macrophages	macrophage	NOUN
bjp-61292	40	26	(	(	PUNCT
bjp-61292	40	27	raw264.7	raw264.7	NOUN
bjp-61292	40	28	)	)	PUNCT
bjp-61292	40	29	were	be	AUX
bjp-61292	40	30	purchased	purchase	VERB
bjp-61292	40	31	from	from	ADP
bjp-61292	40	32	atcc	atcc	PROPN
bjp-61292	40	33	(	(	PUNCT
bjp-61292	40	34	usa	usa	PROPN
bjp-61292	40	35	)	)	PUNCT
bjp-61292	40	36	and	and	CCONJ
bjp-61292	40	37	cultured	cultured	ADJ
bjp-61292	40	38	in	in	ADP
bjp-61292	40	39	dmem	dmem	ADJ
bjp-61292	40	40	medium	medium	NOUN
bjp-61292	40	41	containing	contain	VERB
bjp-61292	40	42	10	10	NUM
bjp-61292	40	43	%	%	NOUN
bjp-61292	40	44	fbs	fbs	ADJ
bjp-61292	40	45	and	and	CCONJ
bjp-61292	40	46	1	1	NUM
bjp-61292	40	47	%	%	NOUN
bjp-61292	40	48	penicillin	penicillin	NOUN
bjp-61292	40	49	/	/	SYM
bjp-61292	40	50	streptomycin	streptomycin	PROPN
bjp-61292	40	51	under	under	ADP
bjp-61292	40	52	the	the	DET
bjp-61292	40	53	condition	condition	NOUN
bjp-61292	40	54	of	of	ADP
bjp-61292	40	55	37	37	NUM
bjp-61292	40	56	℃	℃	PROPN
bjp-61292	40	57	and	and	CCONJ
bjp-61292	40	58	5	5	NUM
bjp-61292	40	59	%	%	NOUN
bjp-61292	40	60	co2	co2	NOUN
bjp-61292	40	61	.	.	PUNCT
bjp-61292	40	62	zoledronic	zoledronic	ADJ
bjp-61292	40	63	acid	acid	PROPN
bjp-61292	40	64	was	be	AUX
bjp-61292	40	65	obtained	obtain	VERB
bjp-61292	40	66	from	from	ADP
bjp-61292	40	67	sigma	sigma	PROPN
bjp-61292	40	68	-	-	PUNCT
bjp-61292	40	69	aldrich	aldrich	PROPN
bjp-61292	40	70	(	(	PUNCT
bjp-61292	40	71	usa	usa	PROPN
bjp-61292	40	72	)	)	PUNCT
bjp-61292	40	73	.	.	PUNCT
bjp-61292	41	1	to	to	PART
bjp-61292	41	2	establish	establish	VERB
bjp-61292	41	3	dkk1	dkk1	PROPN
bjp-61292	41	4	-	-	PUNCT
bjp-61292	41	5	overexpressed	overexpresse	VERB
bjp-61292	41	6	breast	breast	NOUN
bjp-61292	41	7	cancer	cancer	NOUN
bjp-61292	41	8	cells	cell	NOUN
bjp-61292	41	9	,	,	PUNCT
bjp-61292	41	10	cells	cell	NOUN
bjp-61292	41	11	were	be	AUX
bjp-61292	41	12	transfected	transfecte	VERB
bjp-61292	41	13	with	with	ADP
bjp-61292	41	14	the	the	DET
bjp-61292	41	15	vector	vector	NOUN
bjp-61292	41	16	containing	contain	VERB
bjp-61292	41	17	pcdna3.1dkk1	pcdna3.1dkk1	PROPN
bjp-61292	41	18	(	(	PUNCT
bjp-61292	41	19	genscript	genscript	NOUN
bjp-61292	41	20	,	,	PUNCT
bjp-61292	41	21	china	china	PROPN
bjp-61292	41	22	)	)	PUNCT
bjp-61292	41	23	,	,	PUNCT
bjp-61292	41	24	together	together	ADV
bjp-61292	41	25	with	with	ADP
bjp-61292	41	26	the	the	DET
bjp-61292	41	27	transfection	transfection	NOUN
bjp-61292	41	28	reagent	reagent	ADJ
bjp-61292	41	29	lip	lip	NOUN
bjp-61292	41	30	3000	3000	NUM
bjp-61292	41	31	(	(	PUNCT
bjp-61292	41	32	invitrogen	invitrogen	PROPN
bjp-61292	41	33	,	,	PUNCT
bjp-61292	41	34	usa	usa	PROPN
bjp-61292	41	35	)	)	PUNCT
bjp-61292	41	36	.	.	PUNCT
bjp-61292	42	1	the	the	DET
bjp-61292	42	2	efficacy	efficacy	NOUN
bjp-61292	42	3	of	of	ADP
bjp-61292	42	4	transfection	transfection	NOUN
bjp-61292	42	5	was	be	AUX
bjp-61292	42	6	identified	identify	VERB
bjp-61292	42	7	using	use	VERB
bjp-61292	42	8	the	the	DET
bjp-61292	42	9	western	western	ADJ
bjp-61292	42	10	blotting	blot	VERB
bjp-61292	42	11	assay	assay	NOUN
bjp-61292	42	12	.	.	PUNCT
bjp-61292	43	1	extraction	extraction	NOUN
bjp-61292	43	2	of	of	ADP
bjp-61292	43	3	exosomes	exosome	NOUN
bjp-61292	43	4	after	after	ADP
bjp-61292	43	5	incubating	incubate	VERB
bjp-61292	43	6	for	for	ADP
bjp-61292	43	7	48	48	NUM
bjp-61292	43	8	hours	hour	NOUN
bjp-61292	43	9	,	,	PUNCT
bjp-61292	43	10	the	the	DET
bjp-61292	43	11	medium	medium	NOUN
bjp-61292	43	12	was	be	AUX
bjp-61292	43	13	changed	change	VERB
bjp-61292	43	14	to	to	ADP
bjp-61292	43	15	serum	serum	NOUN
bjp-61292	43	16	-	-	PUNCT
bjp-61292	43	17	free	free	ADJ
bjp-61292	43	18	dmem	dmem	ADJ
bjp-61292	43	19	medium	medium	NOUN
bjp-61292	43	20	,	,	PUNCT
bjp-61292	43	21	followed	follow	VERB
bjp-61292	43	22	by	by	ADP
bjp-61292	43	23	48	48	NUM
bjp-61292	43	24	-	-	PUNCT
bjp-61292	43	25	hour	hour	NOUN
bjp-61292	43	26	incubation	incubation	NOUN
bjp-61292	43	27	and	and	CCONJ
bjp-61292	43	28	centrifugation	centrifugation	NOUN
bjp-61292	43	29	at	at	ADP
bjp-61292	43	30	300	300	NUM
bjp-61292	43	31	 	 	SPACE
bjp-61292	43	32	×	×	NOUN
bjp-61292	43	33	 	 	SPACE
bjp-61292	43	34	g	g	NOUN
bjp-61292	43	35	for	for	ADP
bjp-61292	43	36	10	10	NUM
bjp-61292	43	37	 	 	SPACE
bjp-61292	43	38	min	min	NOUN
bjp-61292	43	39	,	,	PUNCT
bjp-61292	43	40	2,000	2,000	NUM
bjp-61292	43	41	 	 	SPACE
bjp-61292	43	42	×	×	NOUN
bjp-61292	43	43	 	 	SPACE
bjp-61292	43	44	g	g	NOUN
bjp-61292	43	45	for	for	ADP
bjp-61292	43	46	10	10	NUM
bjp-61292	43	47	 	 	SPACE
bjp-61292	43	48	min	min	NOUN
bjp-61292	43	49	,	,	PUNCT
bjp-61292	43	50	and	and	CCONJ
bjp-61292	43	51	10,000	10,000	NUM
bjp-61292	43	52	 	 	SPACE
bjp-61292	43	53	×	×	NOUN
bjp-61292	43	54	 	 	SPACE
bjp-61292	43	55	g	g	NOUN
bjp-61292	43	56	for	for	ADP
bjp-61292	43	57	30	30	NUM
bjp-61292	43	58	 	 	SPACE
bjp-61292	43	59	min	min	NOUN
bjp-61292	43	60	at	at	ADP
bjp-61292	43	61	4	4	NUM
bjp-61292	43	62	°	°	ADP
bjp-61292	43	63	c	c	NOUN
bjp-61292	43	64	successively	successively	ADV
bjp-61292	43	65	.	.	PUNCT
bjp-61292	44	1	subsequently	subsequently	ADV
bjp-61292	44	2	,	,	PUNCT
bjp-61292	44	3	the	the	DET
bjp-61292	44	4	supernatants	supernatant	NOUN
bjp-61292	44	5	were	be	AUX
bjp-61292	44	6	collected	collect	VERB
bjp-61292	44	7	and	and	CCONJ
bjp-61292	44	8	centrifugated	centrifugate	VERB
bjp-61292	44	9	at	at	ADP
bjp-61292	44	10	4	4	NUM
bjp-61292	44	11	°	°	ADP
bjp-61292	44	12	c	c	NOUN
bjp-61292	44	13	and	and	CCONJ
bjp-61292	44	14	100,000	100,000	NUM
bjp-61292	44	15	×	×	NOUN
bjp-61292	44	16	 	 	SPACE
bjp-61292	44	17	g	g	NOUN
bjp-61292	44	18	for	for	ADP
bjp-61292	44	19	70	70	NUM
bjp-61292	44	20	min	min	NOUN
bjp-61292	44	21	,	,	PUNCT
bjp-61292	44	22	followed	follow	VERB
bjp-61292	44	23	by	by	ADP
bjp-61292	44	24	washing	washing	NOUN
bjp-61292	44	25	and	and	CCONJ
bjp-61292	44	26	resuspending	resuspend	VERB
bjp-61292	44	27	using	use	VERB
bjp-61292	44	28	the	the	DET
bjp-61292	44	29	pbs	pbs	PROPN
bjp-61292	44	30	buffer	buffer	NOUN
bjp-61292	44	31	.	.	PUNCT
bjp-61292	45	1	the	the	DET
bjp-61292	45	2	extracted	extract	VERB
bjp-61292	45	3	exosomes	exosome	NOUN
bjp-61292	45	4	were	be	AUX
bjp-61292	45	5	stored	store	VERB
bjp-61292	45	6	at	at	ADP
bjp-61292	45	7	-80	-80	NUM
bjp-61292	45	8	°	°	NOUN
bjp-61292	45	9	c	c	NOUN
bjp-61292	45	10	for	for	ADP
bjp-61292	45	11	the	the	DET
bjp-61292	45	12	subsequent	subsequent	ADJ
bjp-61292	45	13	experiments	experiment	NOUN
bjp-61292	45	14	.	.	PUNCT
bjp-61292	46	1	transmission	transmission	NOUN
bjp-61292	46	2	electron	electron	NOUN
bjp-61292	46	3	microscopy	microscopy	NOUN
bjp-61292	46	4	(	(	PUNCT
bjp-61292	46	5	tem	tem	PROPN
bjp-61292	46	6	)	)	PUNCT
bjp-61292	46	7	for	for	ADP
bjp-61292	46	8	the	the	DET
bjp-61292	46	9	identification	identification	NOUN
bjp-61292	46	10	of	of	ADP
bjp-61292	46	11	extracted	extract	VERB
bjp-61292	46	12	exosomes	exosome	NOUN
bjp-61292	46	13	the	the	DET
bjp-61292	46	14	extracted	extract	VERB
bjp-61292	46	15	exosomes	exosome	NOUN
bjp-61292	46	16	were	be	AUX
bjp-61292	46	17	fixed	fix	VERB
bjp-61292	46	18	using	use	VERB
bjp-61292	46	19	2.5	2.5	NUM
bjp-61292	46	20	%	%	NOUN
bjp-61292	46	21	glutaraldehyde	glutaraldehyde	NOUN
bjp-61292	46	22	at	at	ADP
bjp-61292	46	23	4	4	NUM
bjp-61292	46	24	°	°	ADP
bjp-61292	46	25	c	c	NOUN
bjp-61292	46	26	for	for	ADP
bjp-61292	46	27	12	12	NUM
bjp-61292	46	28	hours	hour	NOUN
bjp-61292	46	29	,	,	PUNCT
bjp-61292	46	30	followed	follow	VERB
bjp-61292	46	31	by	by	ADP
bjp-61292	46	32	being	be	AUX
bjp-61292	46	33	loaded	load	VERB
bjp-61292	46	34	onto	onto	ADP
bjp-61292	46	35	formvar	formvar	NOUN
bjp-61292	46	36	/	/	SYM
bjp-61292	46	37	carbon	carbon	NOUN
bjp-61292	46	38	-	-	PUNCT
bjp-61292	46	39	coated	coat	VERB
bjp-61292	46	40	grids	grid	NOUN
bjp-61292	46	41	.	.	PUNCT
bjp-61292	47	1	subsequently	subsequently	ADV
bjp-61292	47	2	,	,	PUNCT
bjp-61292	47	3	the	the	DET
bjp-61292	47	4	samples	sample	NOUN
bjp-61292	47	5	were	be	AUX
bjp-61292	47	6	stained	stain	VERB
bjp-61292	47	7	with	with	ADP
bjp-61292	47	8	aqueous	aqueous	ADJ
bjp-61292	47	9	phosphotungstic	phosphotungstic	NOUN
bjp-61292	47	10	acid	acid	NOUN
bjp-61292	47	11	for	for	ADP
bjp-61292	47	12	several	several	ADJ
bjp-61292	47	13	mins	min	NOUN
bjp-61292	47	14	,	,	PUNCT
bjp-61292	47	15	followed	follow	VERB
bjp-61292	47	16	by	by	ADP
bjp-61292	47	17	taking	take	VERB
bjp-61292	47	18	images	image	NOUN
bjp-61292	47	19	using	use	VERB
bjp-61292	47	20	a	a	DET
bjp-61292	47	21	transmission	transmission	NOUN
bjp-61292	47	22	electron	electron	NOUN
bjp-61292	47	23	microscope	microscope	NOUN
bjp-61292	47	24	(	(	PUNCT
bjp-61292	47	25	laird	laird	PROPN
bjp-61292	47	26	,	,	PUNCT
bjp-61292	47	27	usa	usa	PROPN
bjp-61292	47	28	)	)	PUNCT
bjp-61292	47	29	.	.	PUNCT
bjp-61292	48	1	cell	cell	NOUN
bjp-61292	48	2	viability	viability	NOUN
bjp-61292	48	3	in	in	ADP
bjp-61292	48	4	brief	brief	NOUN
bjp-61292	48	5	,	,	PUNCT
bjp-61292	48	6	after	after	ADP
bjp-61292	48	7	digesting	digest	VERB
bjp-61292	48	8	cells	cell	NOUN
bjp-61292	48	9	using	use	VERB
bjp-61292	48	10	0.25	0.25	NUM
bjp-61292	48	11	%	%	NOUN
bjp-61292	48	12	pancreatin	pancreatin	ADJ
bjp-61292	48	13	,	,	PUNCT
bjp-61292	48	14	cells	cell	NOUN
bjp-61292	48	15	were	be	AUX
bjp-61292	48	16	planted	plant	VERB
bjp-61292	48	17	on	on	ADP
bjp-61292	48	18	96	96	NUM
bjp-61292	48	19	-	-	PUNCT
bjp-61292	48	20	well	well	NOUN
bjp-61292	48	21	plates	plate	NOUN
bjp-61292	48	22	to	to	PART
bjp-61292	48	23	be	be	AUX
bjp-61292	48	24	incubated	incubate	VERB
bjp-61292	48	25	for	for	ADP
bjp-61292	48	26	24	24	NUM
bjp-61292	48	27	hours	hour	NOUN
bjp-61292	48	28	,	,	PUNCT
bjp-61292	48	29	followed	follow	VERB
bjp-61292	48	30	by	by	ADP
bjp-61292	48	31	replacing	replace	VERB
bjp-61292	48	32	the	the	DET
bjp-61292	48	33	culturing	culture	VERB
bjp-61292	48	34	medium	medium	NOUN
bjp-61292	48	35	supplemented	supplement	VERB
bjp-61292	48	36	with	with	ADP
bjp-61292	48	37	5	5	NUM
bjp-61292	48	38	mg	mg	NUM
bjp-61292	48	39	/	/	SYM
bjp-61292	48	40	ml	ml	NOUN
bjp-61292	48	41	mtt	mtt	NOUN
bjp-61292	48	42	solution	solution	NOUN
bjp-61292	48	43	.	.	PUNCT
bjp-61292	49	1	then	then	ADV
bjp-61292	49	2	dimethyl	dimethyl	NOUN
bjp-61292	49	3	sulfoxide	sulfoxide	NOUN
bjp-61292	49	4	was	be	AUX
bjp-61292	49	5	introduced	introduce	VERB
bjp-61292	49	6	following	follow	VERB
bjp-61292	49	7	10	10	NUM
bjp-61292	49	8	min	min	NOUN
bjp-61292	49	9	incubation	incubation	NOUN
bjp-61292	49	10	.	.	PUNCT
bjp-61292	50	1	lastly	lastly	ADV
bjp-61292	50	2	,	,	PUNCT
bjp-61292	50	3	the	the	DET
bjp-61292	50	4	microplate	microplate	NOUN
bjp-61292	50	5	reader	reader	NOUN
bjp-61292	50	6	(	(	PUNCT
bjp-61292	50	7	bruker	bruker	PROPN
bjp-61292	50	8	,	,	PUNCT
bjp-61292	50	9	usa	usa	PROPN
bjp-61292	50	10	)	)	PUNCT
bjp-61292	50	11	was	be	AUX
bjp-61292	50	12	utilized	utilize	VERB
bjp-61292	50	13	to	to	PART
bjp-61292	50	14	detect	detect	VERB
bjp-61292	50	15	the	the	DET
bjp-61292	50	16	absorbance	absorbance	NOUN
bjp-61292	50	17	at	at	ADP
bjp-61292	50	18	490	490	NUM
bjp-61292	50	19	nm	nm	NOUN
bjp-61292	50	20	(	(	PUNCT
bjp-61292	50	21	yan	yan	PROPN
bjp-61292	50	22	et	et	PROPN
bjp-61292	50	23	al	al	PROPN
bjp-61292	50	24	.	.	PROPN
bjp-61292	50	25	,	,	PUNCT
bjp-61292	50	26	2018	2018	NUM
bjp-61292	50	27	)	)	PUNCT
bjp-61292	50	28	.	.	PUNCT
bjp-61292	51	1	wound	wound	NOUN
bjp-61292	51	2	healing	healing	NOUN
bjp-61292	51	3	assay	assay	VERB
bjp-61292	51	4	after	after	ADP
bjp-61292	51	5	seeding	seed	VERB
bjp-61292	51	6	cells	cell	NOUN
bjp-61292	51	7	onto	onto	ADP
bjp-61292	51	8	6	6	NUM
bjp-61292	51	9	-	-	PUNCT
bjp-61292	51	10	well	well	NOUN
bjp-61292	51	11	plates	plate	NOUN
bjp-61292	51	12	to	to	ADP
bjp-61292	51	13	80	80	NUM
bjp-61292	51	14	%	%	NOUN
bjp-61292	51	15	confluence	confluence	NOUN
bjp-61292	51	16	,	,	PUNCT
bjp-61292	51	17	the	the	DET
bjp-61292	51	18	sterile	sterile	ADJ
bjp-61292	51	19	plastic	plastic	NOUN
bjp-61292	51	20	pipette	pipette	NOUN
bjp-61292	51	21	tips	tip	NOUN
bjp-61292	51	22	were	be	AUX
bjp-61292	51	23	utilized	utilize	VERB
bjp-61292	51	24	to	to	PART
bjp-61292	51	25	scrap	scrap	VERB
bjp-61292	51	26	the	the	DET
bjp-61292	51	27	cell	cell	NOUN
bjp-61292	51	28	monolayer	monolayer	NOUN
bjp-61292	51	29	,	,	PUNCT
bjp-61292	51	30	followed	follow	VERB
bjp-61292	51	31	by	by	ADP
bjp-61292	51	32	twice	twice	ADJ
bjp-61292	51	33	washes	wash	NOUN
bjp-61292	51	34	using	use	VERB
bjp-61292	51	35	the	the	DET
bjp-61292	51	36	serum	serum	NOUN
bjp-61292	51	37	-	-	PUNCT
bjp-61292	51	38	free	free	ADJ
bjp-61292	51	39	medium	medium	NOUN
bjp-61292	51	40	.	.	PUNCT
bjp-61292	52	1	after	after	ADP
bjp-61292	52	2	different	different	ADJ
bjp-61292	52	3	strategies	strategy	NOUN
bjp-61292	52	4	for	for	ADP
bjp-61292	52	5	24	24	NUM
bjp-61292	52	6	hours	hour	NOUN
bjp-61292	52	7	,	,	PUNCT
bjp-61292	52	8	images	image	NOUN
bjp-61292	52	9	of	of	ADP
bjp-61292	52	10	the	the	DET
bjp-61292	52	11	wound	wound	NOUN
bjp-61292	52	12	closure	closure	NOUN
bjp-61292	52	13	were	be	AUX
bjp-61292	52	14	taken	take	VERB
bjp-61292	52	15	using	use	VERB
bjp-61292	52	16	the	the	DET
bjp-61292	52	17	inverted	inverted	ADJ
bjp-61292	52	18	microscope	microscope	NOUN
bjp-61292	52	19	(	(	PUNCT
bjp-61292	52	20	laird	laird	PROPN
bjp-61292	52	21	,	,	PUNCT
bjp-61292	52	22	usa	usa	PROPN
bjp-61292	52	23	)	)	PUNCT
bjp-61292	52	24	(	(	PUNCT
bjp-61292	52	25	liu	liu	PROPN
bjp-61292	52	26	et	et	PROPN
bjp-61292	52	27	al	al	PROPN
bjp-61292	52	28	.	.	PROPN
bjp-61292	52	29	,	,	PUNCT
bjp-61292	52	30	2021	2021	NUM
bjp-61292	52	31	)	)	PUNCT
bjp-61292	52	32	.	.	PUNCT
bjp-61292	53	1	clone	clone	NOUN
bjp-61292	53	2	formation	formation	NOUN
bjp-61292	53	3	assay	assay	PROPN
bjp-61292	53	4	breast	breast	NOUN
bjp-61292	53	5	cancer	cancer	NOUN
bjp-61292	53	6	cells	cell	NOUN
bjp-61292	53	7	were	be	AUX
bjp-61292	53	8	planted	plant	VERB
bjp-61292	53	9	into	into	ADP
bjp-61292	53	10	the	the	DET
bjp-61292	53	11	6	6	NUM
bjp-61292	53	12	-	-	PUNCT
bjp-61292	53	13	well	well	NOUN
bjp-61292	53	14	plates	plate	NOUN
bjp-61292	53	15	,	,	PUNCT
bjp-61292	53	16	followed	follow	VERB
bjp-61292	53	17	by	by	ADP
bjp-61292	53	18	being	be	AUX
bjp-61292	53	19	incubated	incubate	VERB
bjp-61292	53	20	for	for	ADP
bjp-61292	53	21	1	1	NUM
bjp-61292	53	22	week	week	NOUN
bjp-61292	53	23	at	at	ADP
bjp-61292	53	24	37	37	NUM
bjp-61292	53	25	°	°	NOUN
bjp-61292	53	26	c	c	NOUN
bjp-61292	53	27	.	.	PUNCT
bjp-61292	54	1	cells	cell	NOUN
bjp-61292	54	2	were	be	AUX
bjp-61292	54	3	then	then	ADV
bjp-61292	54	4	fixed	fix	VERB
bjp-61292	54	5	with	with	ADP
bjp-61292	54	6	4	4	NUM
bjp-61292	54	7	%	%	NOUN
bjp-61292	54	8	formaldehyde	formaldehyde	NOUN
bjp-61292	54	9	for	for	ADP
bjp-61292	54	10	15	15	NUM
bjp-61292	54	11	min	min	NOUN
bjp-61292	54	12	,	,	PUNCT
bjp-61292	54	13	followed	follow	VERB
bjp-61292	54	14	by	by	ADP
bjp-61292	54	15	being	be	AUX
bjp-61292	54	16	stained	stain	VERB
bjp-61292	54	17	with	with	ADP
bjp-61292	54	18	gimsa	gimsa	NOUN
bjp-61292	54	19	.	.	PUNCT
bjp-61292	55	1	lastly	lastly	ADV
bjp-61292	55	2	,	,	PUNCT
bjp-61292	55	3	images	image	NOUN
bjp-61292	55	4	were	be	AUX
bjp-61292	55	5	taken	take	VERB
bjp-61292	55	6	using	use	VERB
bjp-61292	55	7	the	the	DET
bjp-61292	55	8	inverted	inverted	ADJ
bjp-61292	55	9	microscope	microscope	NOUN
bjp-61292	55	10	(	(	PUNCT
bjp-61292	55	11	laird	laird	PROPN
bjp-61292	55	12	,	,	PUNCT
bjp-61292	55	13	usa	usa	PROPN
bjp-61292	55	14	)	)	PUNCT
bjp-61292	55	15	to	to	PART
bjp-61292	55	16	calculate	calculate	VERB
bjp-61292	55	17	the	the	DET
bjp-61292	55	18	number	number	NOUN
bjp-61292	55	19	of	of	ADP
bjp-61292	55	20	clones	clone	NOUN
bjp-61292	55	21	(	(	PUNCT
bjp-61292	55	22	zhou	zhou	X
bjp-61292	55	23	et	et	PROPN
bjp-61292	55	24	al	al	PROPN
bjp-61292	55	25	.	.	PROPN
bjp-61292	55	26	,	,	PUNCT
bjp-61292	55	27	2021	2021	NUM
bjp-61292	55	28	)	)	PUNCT
bjp-61292	55	29	.	.	PUNCT
bjp-61292	56	1	tartrate	tartrate	NOUN
bjp-61292	56	2	-	-	PUNCT
bjp-61292	56	3	resistant	resistant	ADJ
bjp-61292	56	4	acid	acid	NOUN
bjp-61292	56	5	phosphatase	phosphatase	NOUN
bjp-61292	56	6	(	(	PUNCT
bjp-61292	56	7	trap	trap	NOUN
bjp-61292	56	8	)	)	PUNCT
bjp-61292	56	9	staining	stain	VERB
bjp-61292	56	10	after	after	ADP
bjp-61292	56	11	treating	treat	VERB
bjp-61292	56	12	with	with	ADP
bjp-61292	56	13	exosomes	exosome	NOUN
bjp-61292	56	14	,	,	PUNCT
bjp-61292	56	15	raw	raw	ADJ
bjp-61292	56	16	264.7	264.7	NUM
bjp-61292	56	17	cells	cell	NOUN
bjp-61292	56	18	were	be	AUX
bjp-61292	56	19	planted	plant	VERB
bjp-61292	56	20	onto	onto	ADP
bjp-61292	56	21	the	the	DET
bjp-61292	56	22	24	24	NUM
bjp-61292	56	23	-	-	PUNCT
bjp-61292	56	24	well	well	NOUN
bjp-61292	56	25	plates	plate	NOUN
bjp-61292	56	26	,	,	PUNCT
bjp-61292	56	27	followed	follow	VERB
bjp-61292	56	28	by	by	ADP
bjp-61292	56	29	exchanging	exchange	VERB
bjp-61292	56	30	bangladesh	bangladesh	PROPN
bjp-61292	56	31	j	j	PROPN
bjp-61292	56	32	pharmacol	pharmacol	PROPN
bjp-61292	56	33	2022	2022	NUM
bjp-61292	56	34	;	;	PUNCT
bjp-61292	56	35	17	17	NUM
bjp-61292	56	36	:	:	SYM
bjp-61292	56	37	92	92	NUM
bjp-61292	56	38	-	-	SYM
bjp-61292	56	39	101	101	NUM
bjp-61292	56	40	93	93	NUM
bjp-61292	56	41	the	the	DET
bjp-61292	56	42	medium	medium	NOUN
bjp-61292	56	43	every	every	DET
bjp-61292	56	44	2	2	NUM
bjp-61292	56	45	days	day	NOUN
bjp-61292	56	46	.	.	PUNCT
bjp-61292	57	1	after	after	ADP
bjp-61292	57	2	incubating	incubate	VERB
bjp-61292	57	3	for	for	ADP
bjp-61292	57	4	9	9	NUM
bjp-61292	57	5	days	day	NOUN
bjp-61292	57	6	,	,	PUNCT
bjp-61292	57	7	cells	cell	NOUN
bjp-61292	57	8	were	be	AUX
bjp-61292	57	9	fixed	fix	VERB
bjp-61292	57	10	and	and	CCONJ
bjp-61292	57	11	stained	stain	VERB
bjp-61292	57	12	with	with	ADP
bjp-61292	57	13	the	the	DET
bjp-61292	57	14	trap	trap	NOUN
bjp-61292	57	15	activity	activity	NOUN
bjp-61292	57	16	staining	stain	VERB
bjp-61292	57	17	kit	kit	NOUN
bjp-61292	57	18	according	accord	VERB
bjp-61292	57	19	to	to	ADP
bjp-61292	57	20	the	the	DET
bjp-61292	57	21	instruction	instruction	NOUN
bjp-61292	57	22	of	of	ADP
bjp-61292	57	23	the	the	DET
bjp-61292	57	24	manufacturer	manufacturer	NOUN
bjp-61292	57	25	.	.	PUNCT
bjp-61292	58	1	dark	dark	ADJ
bjp-61292	58	2	red	red	PROPN
bjp-61292	58	3	represented	represent	VERB
bjp-61292	58	4	trap	trap	NOUN
bjp-61292	58	5	-	-	PUNCT
bjp-61292	58	6	positive	positive	ADJ
bjp-61292	58	7	cells	cell	NOUN
bjp-61292	58	8	under	under	ADP
bjp-61292	58	9	the	the	DET
bjp-61292	58	10	inverted	inverted	ADJ
bjp-61292	58	11	microscope	microscope	NOUN
bjp-61292	58	12	(	(	PUNCT
bjp-61292	58	13	laird	laird	PROPN
bjp-61292	58	14	,	,	PUNCT
bjp-61292	58	15	usa	usa	PROPN
bjp-61292	58	16	)	)	PUNCT
bjp-61292	58	17	and	and	CCONJ
bjp-61292	58	18	the	the	DET
bjp-61292	58	19	number	number	NOUN
bjp-61292	58	20	of	of	ADP
bjp-61292	58	21	trap	trap	NOUN
bjp-61292	58	22	-	-	PUNCT
bjp-61292	58	23	positive	positive	ADJ
bjp-61292	58	24	multinucleated	multinucleate	VERB
bjp-61292	58	25	cells	cell	NOUN
bjp-61292	58	26	(	(	PUNCT
bjp-61292	58	27	>	>	SYM
bjp-61292	58	28	3	3	NUM
bjp-61292	58	29	nuclei	nucleus	NOUN
bjp-61292	58	30	)	)	PUNCT
bjp-61292	58	31	was	be	AUX
bjp-61292	58	32	counted	count	VERB
bjp-61292	58	33	(	(	PUNCT
bjp-61292	58	34	song	song	NOUN
bjp-61292	58	35	et	et	PROPN
bjp-61292	58	36	al	al	PROPN
bjp-61292	58	37	.	.	PROPN
bjp-61292	58	38	,	,	PUNCT
bjp-61292	58	39	2019	2019	NUM
bjp-61292	58	40	)	)	PUNCT
bjp-61292	58	41	.	.	PUNCT
bjp-61292	59	1	immunostaining	immunostaine	VERB
bjp-61292	59	2	assay	assay	ADJ
bjp-61292	59	3	raw	raw	ADJ
bjp-61292	59	4	264.7	264.7	NUM
bjp-61292	59	5	cells	cell	NOUN
bjp-61292	59	6	were	be	AUX
bjp-61292	59	7	collected	collect	VERB
bjp-61292	59	8	and	and	CCONJ
bjp-61292	59	9	washed	wash	VERB
bjp-61292	59	10	using	use	VERB
bjp-61292	59	11	the	the	DET
bjp-61292	59	12	pbs	pbs	NOUN
bjp-61292	59	13	buffer	buffer	NOUN
bjp-61292	59	14	and	and	CCONJ
bjp-61292	59	15	subsequently	subsequently	ADV
bjp-61292	59	16	fixed	fix	VERB
bjp-61292	59	17	with	with	ADP
bjp-61292	59	18	4	4	NUM
bjp-61292	59	19	%	%	NOUN
bjp-61292	59	20	paraformaldehyde	paraformaldehyde	NOUN
bjp-61292	59	21	on	on	ADP
bjp-61292	59	22	microslide	microslide	NOUN
bjp-61292	59	23	for	for	ADP
bjp-61292	59	24	10	10	NUM
bjp-61292	59	25	min	min	NOUN
bjp-61292	59	26	,	,	PUNCT
bjp-61292	59	27	followed	follow	VERB
bjp-61292	59	28	by	by	ADP
bjp-61292	59	29	3	3	NUM
bjp-61292	59	30	washes	wash	NOUN
bjp-61292	59	31	,	,	PUNCT
bjp-61292	59	32	and	and	CCONJ
bjp-61292	59	33	treated	treat	VERB
bjp-61292	59	34	with	with	ADP
bjp-61292	59	35	triton-100	triton-100	NOUN
bjp-61292	59	36	for	for	ADP
bjp-61292	59	37	10	10	NUM
bjp-61292	59	38	min	min	NOUN
bjp-61292	59	39	.	.	PROPN
bjp-61292	59	40	after	after	ADP
bjp-61292	59	41	blocking	block	VERB
bjp-61292	59	42	,	,	PUNCT
bjp-61292	59	43	cells	cell	NOUN
bjp-61292	59	44	were	be	AUX
bjp-61292	59	45	incubated	incubate	VERB
bjp-61292	59	46	with	with	ADP
bjp-61292	59	47	the	the	DET
bjp-61292	59	48	primary	primary	ADJ
bjp-61292	59	49	antibody	antibody	NOUN
bjp-61292	59	50	against	against	ADP
bjp-61292	59	51	phalloidine	phalloidine	PROPN
bjp-61292	59	52	(	(	PUNCT
bjp-61292	59	53	r&d	r&d	PROPN
bjp-61292	59	54	,	,	PUNCT
bjp-61292	59	55	usa	usa	PROPN
bjp-61292	59	56	)	)	PUNCT
bjp-61292	59	57	,	,	PUNCT
bjp-61292	59	58	pkh67	pkh67	PROPN
bjp-61292	59	59	(	(	PUNCT
bjp-61292	59	60	r&d	r&d	PROPN
bjp-61292	59	61	,	,	PUNCT
bjp-61292	59	62	usa	usa	PROPN
bjp-61292	59	63	)	)	PUNCT
bjp-61292	59	64	at	at	ADP
bjp-61292	59	65	37	37	NUM
bjp-61292	59	66	℃	℃	PROPN
bjp-61292	59	67	for	for	ADP
bjp-61292	59	68	1.5	1.5	NUM
bjp-61292	59	69	hours	hour	NOUN
bjp-61292	59	70	,	,	PUNCT
bjp-61292	59	71	respectively	respectively	ADV
bjp-61292	59	72	,	,	PUNCT
bjp-61292	59	73	followed	follow	VERB
bjp-61292	59	74	by	by	ADP
bjp-61292	59	75	incubation	incubation	NOUN
bjp-61292	59	76	with	with	ADP
bjp-61292	59	77	solution	solution	NOUN
bjp-61292	59	78	diluted	dilute	VERB
bjp-61292	59	79	with	with	ADP
bjp-61292	59	80	secondary	secondary	ADJ
bjp-61292	59	81	antibody	antibody	NOUN
bjp-61292	59	82	(	(	PUNCT
bjp-61292	59	83	r&d	r&d	PROPN
bjp-61292	59	84	,	,	PUNCT
bjp-61292	59	85	usa	usa	PROPN
bjp-61292	59	86	)	)	PUNCT
bjp-61292	59	87	at	at	ADP
bjp-61292	59	88	37	37	NUM
bjp-61292	59	89	℃	℃	PROPN
bjp-61292	59	90	for	for	ADP
bjp-61292	59	91	45	45	NUM
bjp-61292	59	92	min	min	NOUN
bjp-61292	59	93	.	.	PROPN
bjp-61292	60	1	lastly	lastly	ADV
bjp-61292	60	2	,	,	PUNCT
bjp-61292	60	3	the	the	DET
bjp-61292	60	4	slides	slide	NOUN
bjp-61292	60	5	were	be	AUX
bjp-61292	60	6	sealed	seal	VERB
bjp-61292	60	7	using	use	VERB
bjp-61292	60	8	nail	nail	NOUN
bjp-61292	60	9	polish	polish	NOUN
bjp-61292	60	10	after	after	ADP
bjp-61292	60	11	adding	add	VERB
bjp-61292	60	12	the	the	DET
bjp-61292	60	13	hoechst	hoechst	ADJ
bjp-61292	60	14	solution	solution	NOUN
bjp-61292	60	15	.	.	PUNCT
bjp-61292	61	1	the	the	DET
bjp-61292	61	2	fluorescence	fluorescence	NOUN
bjp-61292	61	3	was	be	AUX
bjp-61292	61	4	observed	observe	VERB
bjp-61292	61	5	under	under	ADP
bjp-61292	61	6	the	the	DET
bjp-61292	61	7	fluorescence	fluorescence	NOUN
bjp-61292	61	8	microscope	microscope	NOUN
bjp-61292	61	9	(	(	PUNCT
bjp-61292	61	10	keyence	keyence	NOUN
bjp-61292	61	11	,	,	PUNCT
bjp-61292	61	12	japan	japan	PROPN
bjp-61292	61	13	)	)	PUNCT
bjp-61292	62	1	(	(	PUNCT
bjp-61292	62	2	meng	meng	PROPN
bjp-61292	62	3	et	et	PROPN
bjp-61292	62	4	al	al	PROPN
bjp-61292	62	5	.	.	PROPN
bjp-61292	62	6	,	,	PUNCT
bjp-61292	62	7	2020	2020	NUM
bjp-61292	62	8	)	)	PUNCT
bjp-61292	62	9	.	.	PUNCT
bjp-61292	63	1	elisa	elisa	PROPN
bjp-61292	63	2	assay	assay	VERB
bjp-61292	63	3	the	the	DET
bjp-61292	63	4	release	release	NOUN
bjp-61292	63	5	of	of	ADP
bjp-61292	63	6	ctx	ctx	NOUN
bjp-61292	63	7	,	,	PUNCT
bjp-61292	63	8	ntx	ntx	ADJ
bjp-61292	63	9	,	,	PUNCT
bjp-61292	63	10	and	and	CCONJ
bjp-61292	63	11	tgf	tgf	PROPN
bjp-61292	63	12	-	-	PUNCT
bjp-61292	63	13	β	β	PROPN
bjp-61292	63	14	was	be	AUX
bjp-61292	63	15	determined	determine	VERB
bjp-61292	63	16	using	use	VERB
bjp-61292	63	17	the	the	DET
bjp-61292	63	18	elisa	elisa	PROPN
bjp-61292	63	19	assay	assay	PROPN
bjp-61292	63	20	(	(	PUNCT
bjp-61292	63	21	elabscience	elabscience	NOUN
bjp-61292	63	22	,	,	PUNCT
bjp-61292	63	23	china	china	PROPN
bjp-61292	63	24	)	)	PUNCT
bjp-61292	63	25	.	.	PUNCT
bjp-61292	64	1	in	in	ADP
bjp-61292	64	2	brief	brief	NOUN
bjp-61292	64	3	,	,	PUNCT
bjp-61292	64	4	the	the	DET
bjp-61292	64	5	supernatant	supernatant	NOUN
bjp-61292	64	6	and	and	CCONJ
bjp-61292	64	7	standards	standard	NOUN
bjp-61292	64	8	were	be	AUX
bjp-61292	64	9	collected	collect	VERB
bjp-61292	64	10	and	and	CCONJ
bjp-61292	64	11	seeded	seed	VERB
bjp-61292	64	12	in	in	ADP
bjp-61292	64	13	the	the	DET
bjp-61292	64	14	96	96	NUM
bjp-61292	64	15	-	-	PUNCT
bjp-61292	64	16	well	well	NOUN
bjp-61292	64	17	plates	plate	NOUN
bjp-61292	64	18	,	,	PUNCT
bjp-61292	64	19	followed	follow	VERB
bjp-61292	64	20	by	by	ADP
bjp-61292	64	21	being	be	AUX
bjp-61292	64	22	incubated	incubate	VERB
bjp-61292	64	23	for	for	ADP
bjp-61292	64	24	1	1	NUM
bjp-61292	64	25	hour	hour	NOUN
bjp-61292	64	26	at	at	ADP
bjp-61292	64	27	37	37	NUM
bjp-61292	64	28	℃	℃	PROPN
bjp-61292	64	29	.	.	PUNCT
bjp-61292	65	1	after	after	ADP
bjp-61292	65	2	removing	remove	VERB
bjp-61292	65	3	the	the	DET
bjp-61292	65	4	medium	medium	NOUN
bjp-61292	65	5	,	,	PUNCT
bjp-61292	65	6	the	the	DET
bjp-61292	65	7	conjugate	conjugate	ADJ
bjp-61292	65	8	solution	solution	NOUN
bjp-61292	65	9	was	be	AUX
bjp-61292	65	10	added	add	VERB
bjp-61292	65	11	to	to	PART
bjp-61292	65	12	be	be	AUX
bjp-61292	65	13	incubated	incubate	VERB
bjp-61292	65	14	for	for	ADP
bjp-61292	65	15	30	30	NUM
bjp-61292	65	16	min	min	NOUN
bjp-61292	65	17	,	,	PUNCT
bjp-61292	65	18	followed	follow	VERB
bjp-61292	65	19	by	by	ADP
bjp-61292	65	20	adding	add	VERB
bjp-61292	65	21	the	the	DET
bjp-61292	65	22	tmb	tmb	NOUN
bjp-61292	65	23	solution	solution	NOUN
bjp-61292	65	24	to	to	PART
bjp-61292	65	25	be	be	AUX
bjp-61292	65	26	incubated	incubate	VERB
bjp-61292	65	27	for	for	ADP
bjp-61292	65	28	15	15	NUM
bjp-61292	65	29	min	min	NOUN
bjp-61292	65	30	.	.	PUNCT
bjp-61292	66	1	the	the	DET
bjp-61292	66	2	stop	stop	NOUN
bjp-61292	66	3	solution	solution	NOUN
bjp-61292	66	4	was	be	AUX
bjp-61292	66	5	then	then	ADV
bjp-61292	66	6	added	add	VERB
bjp-61292	66	7	to	to	PART
bjp-61292	66	8	terminate	terminate	VERB
bjp-61292	66	9	the	the	DET
bjp-61292	66	10	reaction	reaction	NOUN
bjp-61292	66	11	,	,	PUNCT
bjp-61292	66	12	followed	follow	VERB
bjp-61292	66	13	by	by	ADP
bjp-61292	66	14	determining	determine	VERB
bjp-61292	66	15	the	the	DET
bjp-61292	66	16	absorbance	absorbance	NOUN
bjp-61292	66	17	at	at	ADP
bjp-61292	66	18	450	450	NUM
bjp-61292	66	19	nm	nm	NOUN
bjp-61292	66	20	with	with	ADP
bjp-61292	66	21	the	the	DET
bjp-61292	66	22	microplate	microplate	NOUN
bjp-61292	66	23	reader	reader	NOUN
bjp-61292	66	24	(	(	PUNCT
bjp-61292	66	25	bruker	bruker	PROPN
bjp-61292	66	26	,	,	PUNCT
bjp-61292	66	27	usa	usa	PROPN
bjp-61292	66	28	)	)	PUNCT
bjp-61292	66	29	to	to	PART
bjp-61292	66	30	determine	determine	VERB
bjp-61292	66	31	the	the	DET
bjp-61292	66	32	concentration	concentration	NOUN
bjp-61292	66	33	of	of	ADP
bjp-61292	66	34	the	the	DET
bjp-61292	66	35	proteins	protein	NOUN
bjp-61292	66	36	(	(	PUNCT
bjp-61292	66	37	gürbüz	gürbüz	NOUN
bjp-61292	66	38	et	et	PROPN
bjp-61292	66	39	al	al	PROPN
bjp-61292	66	40	.	.	PROPN
bjp-61292	66	41	,	,	PUNCT
bjp-61292	66	42	2019	2019	NUM
bjp-61292	66	43	)	)	PUNCT
bjp-61292	66	44	.	.	PUNCT
bjp-61292	67	1	real	real	ADJ
bjp-61292	67	2	-	-	PUNCT
bjp-61292	67	3	time	time	NOUN
bjp-61292	67	4	pcr	pcr	NOUN
bjp-61292	67	5	the	the	DET
bjp-61292	67	6	trizol	trizol	ADJ
bjp-61292	67	7	©	©	PROPN
bjp-61292	67	8	reagent	reagent	NOUN
bjp-61292	67	9	(	(	PUNCT
bjp-61292	67	10	invitrogen	invitrogen	PROPN
bjp-61292	67	11	,	,	PUNCT
bjp-61292	67	12	usa	usa	PROPN
bjp-61292	67	13	)	)	PUNCT
bjp-61292	67	14	was	be	AUX
bjp-61292	67	15	utilized	utilize	VERB
bjp-61292	67	16	for	for	ADP
bjp-61292	67	17	the	the	DET
bjp-61292	67	18	extraction	extraction	NOUN
bjp-61292	67	19	of	of	ADP
bjp-61292	67	20	total	total	ADJ
bjp-61292	67	21	rnas	rna	NOUN
bjp-61292	67	22	from	from	ADP
bjp-61292	67	23	the	the	DET
bjp-61292	67	24	chondrocytes	chondrocyte	NOUN
bjp-61292	67	25	in	in	ADP
bjp-61292	67	26	each	each	DET
bjp-61292	67	27	group	group	NOUN
bjp-61292	67	28	,	,	PUNCT
bjp-61292	67	29	which	which	PRON
bjp-61292	67	30	were	be	AUX
bjp-61292	67	31	further	far	ADV
bjp-61292	67	32	reverse‐transcribed	reverse‐transcribe	VERB
bjp-61292	67	33	to	to	ADP
bjp-61292	67	34	cdna	cdna	PROPN
bjp-61292	67	35	using	use	VERB
bjp-61292	67	36	the	the	DET
bjp-61292	67	37	taqman	taqman	NOUN
bjp-61292	67	38	mirna	mirna	NOUN
bjp-61292	67	39	reverse	reverse	NOUN
bjp-61292	67	40	transcription	transcription	NOUN
bjp-61292	67	41	kit	kit	NOUN
bjp-61292	67	42	(	(	PUNCT
bjp-61292	67	43	invitrogen	invitrogen	PROPN
bjp-61292	67	44	,	,	PUNCT
bjp-61292	67	45	usa	usa	PROPN
bjp-61292	67	46	)	)	PUNCT
bjp-61292	67	47	.	.	PUNCT
bjp-61292	68	1	the	the	DET
bjp-61292	68	2	rt	rt	PROPN
bjp-61292	68	3	-	-	PUNCT
bjp-61292	68	4	pcr	pcr	PROPN
bjp-61292	68	5	was	be	AUX
bjp-61292	68	6	conducted	conduct	VERB
bjp-61292	68	7	with	with	ADP
bjp-61292	68	8	sybr	sybr	NOUN
bjp-61292	68	9	®	®	NOUN
bjp-61292	68	10	green	green	ADJ
bjp-61292	68	11	real‐time	real‐time	PROPN
bjp-61292	68	12	pcr	pcr	PROPN
bjp-61292	68	13	master	master	NOUN
bjp-61292	68	14	mix	mix	NOUN
bjp-61292	68	15	(	(	PUNCT
bjp-61292	68	16	roche	roche	NOUN
bjp-61292	68	17	diagnostics	diagnostic	NOUN
bjp-61292	68	18	,	,	PUNCT
bjp-61292	68	19	switzerland	switzerland	PROPN
bjp-61292	68	20	)	)	PUNCT
bjp-61292	68	21	.	.	PUNCT
bjp-61292	69	1	gapdh	gapdh	NOUN
bjp-61292	69	2	was	be	AUX
bjp-61292	69	3	used	use	VERB
bjp-61292	69	4	for	for	ADP
bjp-61292	69	5	the	the	DET
bjp-61292	69	6	normalization	normalization	NOUN
bjp-61292	69	7	of	of	ADP
bjp-61292	69	8	the	the	DET
bjp-61292	69	9	expression	expression	NOUN
bjp-61292	69	10	of	of	ADP
bjp-61292	69	11	genes	gene	NOUN
bjp-61292	69	12	,	,	PUNCT
bjp-61292	69	13	which	which	PRON
bjp-61292	69	14	was	be	AUX
bjp-61292	69	15	determined	determine	VERB
bjp-61292	69	16	using	use	VERB
bjp-61292	69	17	the	the	DET
bjp-61292	69	18	2−δδct	2−δδct	NUM
bjp-61292	69	19	method	method	NOUN
bjp-61292	69	20	(	(	PUNCT
bjp-61292	69	21	liang	liang	PROPN
bjp-61292	69	22	et	et	PROPN
bjp-61292	69	23	al	al	PROPN
bjp-61292	69	24	.	.	PROPN
bjp-61292	69	25	,	,	PUNCT
bjp-61292	69	26	2007	2007	NUM
bjp-61292	69	27	)	)	PUNCT
bjp-61292	69	28	.	.	PUNCT
bjp-61292	70	1	western	western	ADJ
bjp-61292	70	2	blot	blot	NOUN
bjp-61292	70	3	assay	assay	VERB
bjp-61292	70	4	the	the	DET
bjp-61292	70	5	lysis	lysis	NOUN
bjp-61292	70	6	buffer	buffer	NOUN
bjp-61292	70	7	was	be	AUX
bjp-61292	70	8	utilized	utilize	VERB
bjp-61292	70	9	to	to	PART
bjp-61292	70	10	extract	extract	VERB
bjp-61292	70	11	total	total	ADJ
bjp-61292	70	12	proteins	protein	NOUN
bjp-61292	70	13	from	from	ADP
bjp-61292	70	14	cells	cell	NOUN
bjp-61292	70	15	or	or	CCONJ
bjp-61292	70	16	exosomes	exosome	NOUN
bjp-61292	70	17	and	and	CCONJ
bjp-61292	70	18	the	the	DET
bjp-61292	70	19	isolated	isolated	ADJ
bjp-61292	70	20	proteins	protein	NOUN
bjp-61292	70	21	were	be	AUX
bjp-61292	70	22	quantified	quantify	VERB
bjp-61292	70	23	with	with	ADP
bjp-61292	70	24	the	the	DET
bjp-61292	70	25	bca	bca	PROPN
bjp-61292	70	26	kit	kit	NOUN
bjp-61292	70	27	(	(	PUNCT
bjp-61292	70	28	takara	takara	PROPN
bjp-61292	70	29	,	,	PUNCT
bjp-61292	70	30	japan	japan	PROPN
bjp-61292	70	31	)	)	PUNCT
bjp-61292	70	32	,	,	PUNCT
bjp-61292	70	33	followed	follow	VERB
bjp-61292	70	34	by	by	ADP
bjp-61292	70	35	loading	load	VERB
bjp-61292	70	36	30	30	NUM
bjp-61292	70	37	μg	μg	NOUN
bjp-61292	70	38	proteins	protein	NOUN
bjp-61292	70	39	for	for	ADP
bjp-61292	70	40	each	each	DET
bjp-61292	70	41	sample	sample	NOUN
bjp-61292	70	42	onto	onto	ADP
bjp-61292	70	43	the	the	DET
bjp-61292	70	44	12	12	NUM
bjp-61292	70	45	%	%	NOUN
bjp-61292	70	46	sds	sds	NOUN
bjp-61292	70	47	-	-	PUNCT
bjp-61292	70	48	page	page	NOUN
bjp-61292	70	49	.	.	PUNCT
bjp-61292	71	1	after	after	ADP
bjp-61292	71	2	separating	separate	VERB
bjp-61292	71	3	for	for	ADP
bjp-61292	71	4	1	1	NUM
bjp-61292	71	5	hour	hour	NOUN
bjp-61292	71	6	,	,	PUNCT
bjp-61292	71	7	proteins	protein	NOUN
bjp-61292	71	8	in	in	ADP
bjp-61292	71	9	the	the	DET
bjp-61292	71	10	gel	gel	NOUN
bjp-61292	71	11	were	be	AUX
bjp-61292	71	12	further	far	ADV
bjp-61292	71	13	transferred	transfer	VERB
bjp-61292	71	14	onto	onto	ADP
bjp-61292	71	15	the	the	DET
bjp-61292	71	16	pvdf	pvdf	PROPN
bjp-61292	71	17	membrane	membrane	NOUN
bjp-61292	71	18	(	(	PUNCT
bjp-61292	71	19	takara	takara	PROPN
bjp-61292	71	20	,	,	PUNCT
bjp-61292	71	21	japan	japan	PROPN
bjp-61292	71	22	)	)	PUNCT
bjp-61292	71	23	,	,	PUNCT
bjp-61292	71	24	followed	follow	VERB
bjp-61292	71	25	by	by	ADP
bjp-61292	71	26	being	be	AUX
bjp-61292	71	27	incubated	incubate	VERB
bjp-61292	71	28	with	with	ADP
bjp-61292	71	29	5	5	NUM
bjp-61292	71	30	%	%	NOUN
bjp-61292	71	31	skim	skim	NOUN
bjp-61292	71	32	milk	milk	NOUN
bjp-61292	71	33	.	.	PUNCT
bjp-61292	72	1	then	then	ADV
bjp-61292	72	2	,	,	PUNCT
bjp-61292	72	3	the	the	DET
bjp-61292	72	4	membrane	membrane	NOUN
bjp-61292	72	5	was	be	AUX
bjp-61292	72	6	incubated	incubate	VERB
bjp-61292	72	7	with	with	ADP
bjp-61292	72	8	the	the	DET
bjp-61292	72	9	primary	primary	ADJ
bjp-61292	72	10	antibody	antibody	NOUN
bjp-61292	72	11	against	against	ADP
bjp-61292	72	12	dkk1	dkk1	PROPN
bjp-61292	72	13	(	(	PUNCT
bjp-61292	72	14	1:1000	1:1000	NUM
bjp-61292	72	15	)	)	PUNCT
bjp-61292	72	16	,	,	PUNCT
bjp-61292	72	17	cd63	cd63	PROPN
bjp-61292	72	18	(	(	PUNCT
bjp-61292	72	19	1:1000	1:1000	NUM
bjp-61292	72	20	)	)	PUNCT
bjp-61292	72	21	,	,	PUNCT
bjp-61292	72	22	cd81	cd81	PROPN
bjp-61292	72	23	(	(	PUNCT
bjp-61292	72	24	1:1000	1:1000	NUM
bjp-61292	72	25	)	)	PUNCT
bjp-61292	72	26	,	,	PUNCT
bjp-61292	72	27	trap	trap	NOUN
bjp-61292	72	28	(	(	PUNCT
bjp-61292	72	29	1:1000	1:1000	NUM
bjp-61292	72	30	)	)	PUNCT
bjp-61292	72	31	,	,	PUNCT
bjp-61292	72	32	oscar	oscar	NOUN
bjp-61292	72	33	(	(	PUNCT
bjp-61292	72	34	1:1000	1:1000	NUM
bjp-61292	72	35	)	)	PUNCT
bjp-61292	72	36	,	,	PUNCT
bjp-61292	72	37	c	c	X
bjp-61292	72	38	-	-	PUNCT
bjp-61292	72	39	fos	fos	X
bjp-61292	72	40	(	(	PUNCT
bjp-61292	72	41	1:1000	1:1000	NUM
bjp-61292	72	42	)	)	PUNCT
bjp-61292	72	43	,	,	PUNCT
bjp-61292	72	44	nfatcl	nfatcl	INTJ
bjp-61292	72	45	(	(	PUNCT
bjp-61292	72	46	1:1000	1:1000	NUM
bjp-61292	72	47	)	)	PUNCT
bjp-61292	72	48	,	,	PUNCT
bjp-61292	72	49	e	e	NOUN
bjp-61292	72	50	-	-	NOUN
bjp-61292	72	51	cadherin	cadherin	NOUN
bjp-61292	72	52	(	(	PUNCT
bjp-61292	72	53	1:1000	1:1000	NUM
bjp-61292	72	54	)	)	PUNCT
bjp-61292	72	55	,	,	PUNCT
bjp-61292	72	56	β	β	NOUN
bjp-61292	72	57	-	-	NOUN
bjp-61292	72	58	catenin	catenin	ADJ
bjp-61292	72	59	(	(	PUNCT
bjp-61292	72	60	1:1000	1:1000	NUM
bjp-61292	72	61	)	)	PUNCT
bjp-61292	72	62	,	,	PUNCT
bjp-61292	72	63	n	n	CCONJ
bjp-61292	72	64	-	-	PUNCT
bjp-61292	72	65	cadherin	cadherin	NOUN
bjp-61292	72	66	(	(	PUNCT
bjp-61292	72	67	1:1000	1:1000	NUM
bjp-61292	72	68	)	)	PUNCT
bjp-61292	72	69	,	,	PUNCT
bjp-61292	72	70	vimentin	vimentin	X
bjp-61292	72	71	(	(	PUNCT
bjp-61292	72	72	1:1000	1:1000	NUM
bjp-61292	72	73	)	)	PUNCT
bjp-61292	72	74	,	,	PUNCT
bjp-61292	72	75	smad2	smad2	X
bjp-61292	72	76	(	(	PUNCT
bjp-61292	72	77	1:1000	1:1000	NUM
bjp-61292	72	78	)	)	PUNCT
bjp-61292	72	79	,	,	PUNCT
bjp-61292	72	80	smad3	smad3	X
bjp-61292	72	81	(	(	PUNCT
bjp-61292	72	82	1:1000	1:1000	NUM
bjp-61292	72	83	)	)	PUNCT
bjp-61292	72	84	,	,	PUNCT
bjp-61292	72	85	snail	snail	NOUN
bjp-61292	72	86	(	(	PUNCT
bjp-61292	72	87	1:1000	1:1000	NUM
bjp-61292	72	88	)	)	PUNCT
bjp-61292	72	89	,	,	PUNCT
bjp-61292	72	90	twist	twist	NOUN
bjp-61292	72	91	(	(	PUNCT
bjp-61292	72	92	1:1000	1:1000	NUM
bjp-61292	72	93	)	)	PUNCT
bjp-61292	72	94	,	,	PUNCT
bjp-61292	72	95	zeb1	zeb1	PROPN
bjp-61292	72	96	(	(	PUNCT
bjp-61292	72	97	1:1000	1:1000	NUM
bjp-61292	72	98	)	)	PUNCT
bjp-61292	72	99	,	,	PUNCT
bjp-61292	72	100	zeb2	zeb2	PROPN
bjp-61292	72	101	(	(	PUNCT
bjp-61292	72	102	1:1000	1:1000	NUM
bjp-61292	72	103	)	)	PUNCT
bjp-61292	72	104	,	,	PUNCT
bjp-61292	72	105	and	and	CCONJ
bjp-61292	72	106	gapdh	gapdh	NOUN
bjp-61292	72	107	(	(	PUNCT
bjp-61292	72	108	1:1000	1:1000	NUM
bjp-61292	72	109	)	)	PUNCT
bjp-61292	72	110	.	.	PUNCT
bjp-61292	73	1	then	then	ADV
bjp-61292	73	2	the	the	DET
bjp-61292	73	3	secondary	secondary	ADJ
bjp-61292	73	4	antibody	antibody	NOUN
bjp-61292	73	5	(	(	PUNCT
bjp-61292	73	6	1:2000	1:2000	NUM
bjp-61292	73	7	)	)	PUNCT
bjp-61292	73	8	was	be	AUX
bjp-61292	73	9	utilized	utilize	VERB
bjp-61292	73	10	to	to	PART
bjp-61292	73	11	incubate	incubate	VERB
bjp-61292	73	12	with	with	ADP
bjp-61292	73	13	the	the	DET
bjp-61292	73	14	membrane	membrane	NOUN
bjp-61292	73	15	for	for	ADP
bjp-61292	73	16	1.5	1.5	NUM
bjp-61292	73	17	hours	hour	NOUN
bjp-61292	73	18	under	under	ADP
bjp-61292	73	19	the	the	DET
bjp-61292	73	20	room	room	NOUN
bjp-61292	73	21	temperature	temperature	NOUN
bjp-61292	73	22	.	.	PUNCT
bjp-61292	74	1	primary	primary	ADJ
bjp-61292	74	2	and	and	CCONJ
bjp-61292	74	3	secondary	secondary	ADJ
bjp-61292	74	4	antibodies	antibody	NOUN
bjp-61292	74	5	were	be	AUX
bjp-61292	74	6	collected	collect	VERB
bjp-61292	74	7	from	from	ADP
bjp-61292	74	8	affintiy	affintiy	ADJ
bjp-61292	74	9	,	,	PUNCT
bjp-61292	74	10	australia	australia	PROPN
bjp-61292	74	11	.	.	PUNCT
bjp-61292	75	1	lastly	lastly	ADV
bjp-61292	75	2	,	,	PUNCT
bjp-61292	75	3	the	the	DET
bjp-61292	75	4	bands	band	NOUN
bjp-61292	75	5	were	be	AUX
bjp-61292	75	6	incubated	incubate	VERB
bjp-61292	75	7	with	with	ADP
bjp-61292	75	8	the	the	DET
bjp-61292	75	9	ecl	ecl	NOUN
bjp-61292	75	10	solution	solution	NOUN
bjp-61292	75	11	,	,	PUNCT
bjp-61292	75	12	followed	follow	VERB
bjp-61292	75	13	by	by	ADP
bjp-61292	75	14	quantification	quantification	NOUN
bjp-61292	75	15	using	use	VERB
bjp-61292	75	16	the	the	DET
bjp-61292	75	17	image	image	NOUN
bjp-61292	75	18	j	j	PROPN
bjp-61292	75	19	software	software	NOUN
bjp-61292	75	20	(	(	PUNCT
bjp-61292	75	21	ohno	ohno	PROPN
bjp-61292	75	22	et	et	PROPN
bjp-61292	75	23	al	al	PROPN
bjp-61292	75	24	.	.	PROPN
bjp-61292	75	25	,	,	PUNCT
bjp-61292	75	26	2013	2013	NUM
bjp-61292	75	27	)	)	PUNCT
bjp-61292	75	28	.	.	PUNCT
bjp-61292	76	1	statistical	statistical	ADJ
bjp-61292	76	2	analysis	analysis	NOUN
bjp-61292	76	3	data	datum	NOUN
bjp-61292	76	4	achieved	achieve	VERB
bjp-61292	76	5	in	in	ADP
bjp-61292	76	6	the	the	DET
bjp-61292	76	7	present	present	ADJ
bjp-61292	76	8	study	study	NOUN
bjp-61292	76	9	were	be	AUX
bjp-61292	76	10	presented	present	VERB
bjp-61292	76	11	as	as	ADP
bjp-61292	76	12	mean	mean	NOUN
bjp-61292	76	13	±	±	NUM
bjp-61292	76	14	sd	sd	NOUN
bjp-61292	76	15	and	and	CCONJ
bjp-61292	76	16	analyzed	analyze	VERB
bjp-61292	76	17	using	use	VERB
bjp-61292	76	18	the	the	DET
bjp-61292	76	19	graphpad	graphpad	NOUN
bjp-61292	76	20	software	software	NOUN
bjp-61292	76	21	.	.	PUNCT
bjp-61292	77	1	the	the	DET
bjp-61292	77	2	student	student	NOUN
bjp-61292	77	3	’s	’s	PART
bjp-61292	77	4	t	t	PROPN
bjp-61292	77	5	-	-	PUNCT
bjp-61292	77	6	test	test	NOUN
bjp-61292	77	7	was	be	AUX
bjp-61292	77	8	used	use	VERB
bjp-61292	77	9	to	to	PART
bjp-61292	77	10	analyze	analyze	VERB
bjp-61292	77	11	the	the	DET
bjp-61292	77	12	difference	difference	NOUN
bjp-61292	77	13	between	between	ADP
bjp-61292	77	14	2	2	NUM
bjp-61292	77	15	groups	group	NOUN
bjp-61292	77	16	and	and	CCONJ
bjp-61292	77	17	the	the	DET
bjp-61292	77	18	one	one	NUM
bjp-61292	77	19	-	-	PUNCT
bjp-61292	77	20	way	way	NOUN
bjp-61292	77	21	anova	anova	PROPN
bjp-61292	77	22	method	method	NOUN
bjp-61292	77	23	was	be	AUX
bjp-61292	77	24	used	use	VERB
bjp-61292	77	25	to	to	PART
bjp-61292	77	26	analyze	analyze	VERB
bjp-61292	77	27	the	the	DET
bjp-61292	77	28	differences	difference	NOUN
bjp-61292	77	29	among	among	ADP
bjp-61292	77	30	groups	group	NOUN
bjp-61292	77	31	.	.	PUNCT
bjp-61292	78	1	p<0.05	p<0.05	NOUN
bjp-61292	78	2	was	be	AUX
bjp-61292	78	3	considered	consider	VERB
bjp-61292	78	4	a	a	DET
bjp-61292	78	5	significant	significant	ADJ
bjp-61292	78	6	difference	difference	NOUN
bjp-61292	78	7	.	.	PUNCT
bjp-61292	79	1	box	box	PROPN
bjp-61292	80	1	i	i	PRON
bjp-61292	80	2	:	:	PUNCT
bjp-61292	80	3	transwell	transwell	NOUN
bjp-61292	80	4	invasion	invasion	NOUN
bjp-61292	80	5	assay	assay	VERB
bjp-61292	80	6	principle	principle	NOUN
bjp-61292	80	7	the	the	DET
bjp-61292	80	8	migration	migration	NOUN
bjp-61292	80	9	assay	assay	NOUN
bjp-61292	80	10	is	be	AUX
bjp-61292	80	11	the	the	DET
bjp-61292	80	12	change	change	NOUN
bjp-61292	80	13	of	of	ADP
bjp-61292	80	14	the	the	DET
bjp-61292	80	15	cell	cell	NOUN
bjp-61292	80	16	-	-	PUNCT
bjp-61292	80	17	covered	cover	VERB
bjp-61292	80	18	area	area	NOUN
bjp-61292	80	19	(	(	PUNCT
bjp-61292	80	20	gap	gap	NOUN
bjp-61292	80	21	closure	closure	NOUN
bjp-61292	80	22	)	)	PUNCT
bjp-61292	80	23	over	over	ADP
bjp-61292	80	24	time	time	NOUN
bjp-61292	80	25	.	.	PUNCT
bjp-61292	81	1	the	the	DET
bjp-61292	81	2	cells	cell	NOUN
bjp-61292	81	3	are	be	AUX
bjp-61292	81	4	monitored	monitor	VERB
bjp-61292	81	5	immediately	immediately	ADV
bjp-61292	81	6	after	after	ADP
bjp-61292	81	7	the	the	DET
bjp-61292	81	8	gap	gap	NOUN
bjp-61292	81	9	creation	creation	NOUN
bjp-61292	81	10	,	,	PUNCT
bjp-61292	81	11	in	in	ADP
bjp-61292	81	12	most	most	ADJ
bjp-61292	81	13	cases	case	NOUN
bjp-61292	81	14	by	by	ADP
bjp-61292	81	15	using	use	VERB
bjp-61292	81	16	inverted	inverted	ADJ
bjp-61292	81	17	microscopy	microscopy	NOUN
bjp-61292	81	18	.	.	PUNCT
bjp-61292	82	1	requirements	requirement	NOUN
bjp-61292	82	2	crystal	crystal	PROPN
bjp-61292	82	3	violet	violet	NOUN
bjp-61292	82	4	,	,	PUNCT
bjp-61292	82	5	fetal	fetal	ADJ
bjp-61292	82	6	bovine	bovine	NOUN
bjp-61292	82	7	serum	serum	NOUN
bjp-61292	82	8	(	(	PUNCT
bjp-61292	82	9	10	10	NUM
bjp-61292	82	10	%	%	NOUN
bjp-61292	82	11	)	)	PUNCT
bjp-61292	82	12	,	,	PUNCT
bjp-61292	82	13	incubator	incubator	NOUN
bjp-61292	82	14	with	with	ADP
bjp-61292	82	15	5	5	NUM
bjp-61292	82	16	%	%	NOUN
bjp-61292	82	17	co2	co2	NOUN
bjp-61292	82	18	,	,	PUNCT
bjp-61292	82	19	breast	breast	NOUN
bjp-61292	82	20	cancer	cancer	NOUN
bjp-61292	82	21	cells	cell	NOUN
bjp-61292	82	22	(	(	PUNCT
bjp-61292	82	23	mda	mda	NOUN
bjp-61292	82	24	-	-	PUNCT
bjp-61292	82	25	mb-453	mb-453	PROPN
bjp-61292	82	26	and	and	CCONJ
bjp-61292	82	27	mda	mda	PROPN
bjp-61292	82	28	-	-	PUNCT
bjp-61292	82	29	mb-231	mb-231	PROPN
bjp-61292	82	30	)	)	PUNCT
bjp-61292	82	31	suspensions	suspension	NOUN
bjp-61292	82	32	(	(	PUNCT
bjp-61292	82	33	1×105	1×105	NUM
bjp-61292	82	34	cells	cell	NOUN
bjp-61292	82	35	)	)	PUNCT
bjp-61292	82	36	,	,	PUNCT
bjp-61292	82	37	rpmi	rpmi	VERB
bjp-61292	82	38	1640	1640	NUM
bjp-61292	82	39	medium	medium	ADJ
bjp-61292	82	40	,	,	PUNCT
bjp-61292	82	41	zoledronic	zoledronic	ADJ
bjp-61292	82	42	acid	acid	NOUN
bjp-61292	82	43	,	,	PUNCT
bjp-61292	82	44	paraformaldehyde	paraformaldehyde	NOUN
bjp-61292	82	45	,	,	PUNCT
bjp-61292	82	46	inverted	inverted	ADJ
bjp-61292	82	47	microscope	microscope	NOUN
bjp-61292	82	48	(	(	PUNCT
bjp-61292	82	49	laird	laird	PROPN
bjp-61292	82	50	,	,	PUNCT
bjp-61292	82	51	usa	usa	PROPN
bjp-61292	82	52	)	)	PUNCT
bjp-61292	82	53	,	,	PUNCT
bjp-61292	82	54	phosphate	phosphate	NOUN
bjp-61292	82	55	-	-	PUNCT
bjp-61292	82	56	buffered	buffer	VERB
bjp-61292	82	57	saline	saline	NOUN
bjp-61292	82	58	,	,	PUNCT
bjp-61292	82	59	transwell	transwell	NOUN
bjp-61292	82	60	chamber	chamber	NOUN
bjp-61292	82	61	(	(	PUNCT
bjp-61292	82	62	corning	corning	PROPN
bjp-61292	82	63	,	,	PUNCT
bjp-61292	82	64	usa	usa	PROPN
bjp-61292	82	65	)	)	PUNCT
bjp-61292	82	66	procedure	procedure	NOUN
bjp-61292	82	67	step	step	NOUN
bjp-61292	82	68	1	1	NUM
bjp-61292	82	69	:	:	PUNCT
bjp-61292	82	70	the	the	DET
bjp-61292	82	71	cell	cell	NOUN
bjp-61292	82	72	suspensions	suspension	NOUN
bjp-61292	82	73	(	(	PUNCT
bjp-61292	82	74	0.1	0.1	NUM
bjp-61292	82	75	ml	ml	NOUN
bjp-61292	82	76	)	)	PUNCT
bjp-61292	82	77	containing	contain	VERB
bjp-61292	82	78	1	1	NUM
bjp-61292	82	79	,	,	PUNCT
bjp-61292	82	80	5	5	NUM
bjp-61292	82	81	,	,	PUNCT
bjp-61292	82	82	10	10	NUM
bjp-61292	82	83	,	,	PUNCT
bjp-61292	82	84	and	and	CCONJ
bjp-61292	82	85	100	100	NUM
bjp-61292	82	86	μmol	μmol	NOUN
bjp-61292	82	87	/	/	SYM
bjp-61292	82	88	l	l	NOUN
bjp-61292	82	89	zoledronic	zoledronic	ADJ
bjp-61292	82	90	acid	acid	NOUN
bjp-61292	82	91	were	be	AUX
bjp-61292	82	92	seeded	seed	VERB
bjp-61292	82	93	into	into	ADP
bjp-61292	82	94	the	the	DET
bjp-61292	82	95	transwell	transwell	NOUN
bjp-61292	82	96	upper	upper	ADJ
bjp-61292	82	97	chamber	chamber	NOUN
bjp-61292	82	98	.	.	PUNCT
bjp-61292	83	1	step	step	NOUN
bjp-61292	83	2	2	2	NUM
bjp-61292	83	3	:	:	PUNCT
bjp-61292	83	4	the	the	DET
bjp-61292	83	5	medium	medium	NOUN
bjp-61292	83	6	(	(	PUNCT
bjp-61292	83	7	0.6	0.6	NUM
bjp-61292	83	8	ml	ml	NOUN
bjp-61292	83	9	of	of	ADP
bjp-61292	83	10	rpmi	rpmi	NOUN
bjp-61292	83	11	1640	1640	NUM
bjp-61292	83	12	medium	medium	NOUN
bjp-61292	83	13	)	)	PUNCT
bjp-61292	83	14	containing	contain	VERB
bjp-61292	83	15	1	1	NUM
bjp-61292	83	16	%	%	NOUN
bjp-61292	83	17	fetal	fetal	ADJ
bjp-61292	83	18	bovine	bovine	NOUN
bjp-61292	83	19	serum	serum	NOUN
bjp-61292	83	20	was	be	AUX
bjp-61292	83	21	added	add	VERB
bjp-61292	83	22	into	into	ADP
bjp-61292	83	23	the	the	DET
bjp-61292	83	24	lower	low	ADJ
bjp-61292	83	25	chamber	chamber	NOUN
bjp-61292	83	26	step	step	NOUN
bjp-61292	83	27	3	3	NUM
bjp-61292	83	28	:	:	PUNCT
bjp-61292	83	29	all	all	DET
bjp-61292	83	30	chambers	chamber	NOUN
bjp-61292	83	31	were	be	AUX
bjp-61292	83	32	incubated	incubate	VERB
bjp-61292	83	33	for	for	ADP
bjp-61292	83	34	24	24	NUM
bjp-61292	83	35	hours	hour	NOUN
bjp-61292	83	36	at	at	ADP
bjp-61292	83	37	37	37	NUM
bjp-61292	83	38	°	°	ADP
bjp-61292	83	39	c	c	NOUN
bjp-61292	83	40	in	in	ADP
bjp-61292	83	41	a	a	DET
bjp-61292	83	42	humidified	humidify	VERB
bjp-61292	83	43	air	air	NOUN
bjp-61292	83	44	containing	contain	VERB
bjp-61292	83	45	5	5	NUM
bjp-61292	83	46	%	%	NOUN
bjp-61292	83	47	co2	co2	NOUN
bjp-61292	83	48	.	.	PUNCT
bjp-61292	84	1	step	step	NOUN
bjp-61292	84	2	4	4	NUM
bjp-61292	84	3	:	:	PUNCT
bjp-61292	84	4	then	then	ADV
bjp-61292	84	5	,	,	PUNCT
bjp-61292	84	6	the	the	DET
bjp-61292	84	7	upper	upper	ADJ
bjp-61292	84	8	surface	surface	NOUN
bjp-61292	84	9	of	of	ADP
bjp-61292	84	10	the	the	DET
bjp-61292	84	11	membrane	membrane	NOUN
bjp-61292	84	12	was	be	AUX
bjp-61292	84	13	removed	remove	VERB
bjp-61292	84	14	.	.	PUNCT
bjp-61292	85	1	step	step	NOUN
bjp-61292	85	2	5	5	NUM
bjp-61292	85	3	:	:	PUNCT
bjp-61292	85	4	cells	cell	NOUN
bjp-61292	85	5	in	in	ADP
bjp-61292	85	6	the	the	DET
bjp-61292	85	7	lower	low	ADJ
bjp-61292	85	8	chamber	chamber	NOUN
bjp-61292	85	9	were	be	AUX
bjp-61292	85	10	fixed	fix	VERB
bjp-61292	85	11	with	with	ADP
bjp-61292	85	12	4	4	NUM
bjp-61292	85	13	%	%	NOUN
bjp-61292	85	14	paraformaldehyde	paraformaldehyde	NOUN
bjp-61292	85	15	for	for	ADP
bjp-61292	85	16	10	10	NUM
bjp-61292	85	17	min	min	NOUN
bjp-61292	85	18	after	after	ADP
bjp-61292	85	19	removing	remove	VERB
bjp-61292	85	20	the	the	DET
bjp-61292	85	21	transwell	transwell	NOUN
bjp-61292	85	22	chamber	chamber	NOUN
bjp-61292	85	23	.	.	PUNCT
bjp-61292	86	1	step	step	NOUN
bjp-61292	86	2	6	6	NUM
bjp-61292	86	3	:	:	PUNCT
bjp-61292	86	4	the	the	DET
bjp-61292	86	5	cells	cell	NOUN
bjp-61292	86	6	were	be	AUX
bjp-61292	86	7	stained	stain	VERB
bjp-61292	86	8	with	with	ADP
bjp-61292	86	9	0.1	0.1	NUM
bjp-61292	86	10	%	%	NOUN
bjp-61292	86	11	crystal	crystal	NOUN
bjp-61292	86	12	violet	violet	NOUN
bjp-61292	86	13	for	for	ADP
bjp-61292	86	14	25	25	NUM
bjp-61292	86	15	min	min	NOUN
bjp-61292	86	16	,	,	PUNCT
bjp-61292	86	17	washed	wash	VERB
bjp-61292	86	18	with	with	ADP
bjp-61292	86	19	phosphate	phosphate	NOUN
bjp-61292	86	20	-	-	PUNCT
bjp-61292	86	21	buffered	buffer	VERB
bjp-61292	86	22	saline	saline	NOUN
bjp-61292	86	23	,	,	PUNCT
bjp-61292	86	24	placed	place	VERB
bjp-61292	86	25	under	under	ADP
bjp-61292	86	26	inverted	inverted	ADJ
bjp-61292	86	27	microscope	microscope	NOUN
bjp-61292	86	28	and	and	CCONJ
bjp-61292	86	29	photographed	photograph	VERB
bjp-61292	86	30	five	five	NUM
bjp-61292	86	31	random	random	ADJ
bjp-61292	86	32	fields	field	NOUN
bjp-61292	86	33	.	.	PUNCT
bjp-61292	87	1	each	each	DET
bjp-61292	87	2	treatment	treatment	NOUN
bjp-61292	87	3	was	be	AUX
bjp-61292	87	4	repeated	repeat	VERB
bjp-61292	87	5	three	three	NUM
bjp-61292	87	6	times	time	NOUN
bjp-61292	87	7	.	.	PUNCT
bjp-61292	88	1	reference	reference	NOUN
bjp-61292	88	2	yang	yang	PROPN
bjp-61292	88	3	et	et	PROPN
bjp-61292	88	4	al	al	PROPN
bjp-61292	88	5	.	.	PROPN
bjp-61292	88	6	,	,	PUNCT
bjp-61292	88	7	2020	2020	NUM
bjp-61292	88	8	reference	reference	NOUN
bjp-61292	88	9	(	(	PUNCT
bjp-61292	88	10	video	video	NOUN
bjp-61292	88	11	)	)	PUNCT
bjp-61292	88	12	chen	chen	PROPN
bjp-61292	88	13	,	,	PUNCT
bjp-61292	88	14	2018	2018	NUM
bjp-61292	88	15	;	;	PUNCT
bjp-61292	88	16	guo	guo	PROPN
bjp-61292	88	17	et	et	PROPN
bjp-61292	88	18	al	al	PROPN
bjp-61292	88	19	.	.	PROPN
bjp-61292	88	20	,	,	PUNCT
bjp-61292	88	21	2021	2021	NUM
bjp-61292	88	22	94	94	NUM
bjp-61292	88	23	bangladesh	bangladesh	PROPN
bjp-61292	88	24	j	j	PROPN
bjp-61292	88	25	pharmacol	pharmacol	PROPN
bjp-61292	88	26	2022	2022	NUM
bjp-61292	88	27	;	;	PUNCT
bjp-61292	88	28	17	17	NUM
bjp-61292	88	29	:	:	SYM
bjp-61292	88	30	92	92	NUM
bjp-61292	88	31	-	-	SYM
bjp-61292	88	32	101	101	NUM
bjp-61292	88	33	results	result	NOUN
bjp-61292	88	34	dkk1	dkk1	PROPN
bjp-61292	88	35	could	could	AUX
bjp-61292	88	36	be	be	AUX
bjp-61292	88	37	delivered	deliver	VERB
bjp-61292	88	38	by	by	ADP
bjp-61292	88	39	zoledronic	zoledronic	ADJ
bjp-61292	88	40	acid	acid	NOUN
bjp-61292	88	41	-	-	PUNCT
bjp-61292	88	42	treated	treat	VERB
bjp-61292	88	43	exosomes	exosome	NOUN
bjp-61292	88	44	derived	derive	VERB
bjp-61292	88	45	from	from	ADP
bjp-61292	88	46	breast	breast	NOUN
bjp-61292	88	47	cancer	cancer	NOUN
bjp-61292	88	48	cells	cell	NOUN
bjp-61292	88	49	firstly	firstly	ADV
bjp-61292	88	50	,	,	PUNCT
bjp-61292	88	51	2	2	NUM
bjp-61292	88	52	breast	breast	NOUN
bjp-61292	88	53	cancer	cancer	NOUN
bjp-61292	88	54	cell	cell	NOUN
bjp-61292	88	55	lines	line	NOUN
bjp-61292	88	56	with	with	ADP
bjp-61292	88	57	different	different	ADJ
bjp-61292	88	58	malignant	malignant	ADJ
bjp-61292	88	59	degrees	degree	NOUN
bjp-61292	88	60	,	,	PUNCT
bjp-61292	88	61	mda	mda	NOUN
bjp-61292	88	62	-	-	PUNCT
bjp-61292	88	63	mb-453	mb-453	PROPN
bjp-61292	88	64	(	(	PUNCT
bjp-61292	88	65	lower	low	ADJ
bjp-61292	88	66	malignant	malignant	ADJ
bjp-61292	88	67	degree	degree	NOUN
bjp-61292	88	68	)	)	PUNCT
bjp-61292	88	69	and	and	CCONJ
bjp-61292	88	70	mda	mda	PROPN
bjp-61292	88	71	-	-	PUNCT
bjp-61292	88	72	mb-231	mb-231	PROPN
bjp-61292	88	73	(	(	PUNCT
bjp-61292	88	74	higher	high	ADJ
bjp-61292	88	75	malignant	malignant	ADJ
bjp-61292	88	76	degree	degree	NOUN
bjp-61292	88	77	)	)	PUNCT
bjp-61292	88	78	,	,	PUNCT
bjp-61292	88	79	were	be	AUX
bjp-61292	88	80	chosen	choose	VERB
bjp-61292	88	81	for	for	ADP
bjp-61292	88	82	the	the	DET
bjp-61292	88	83	investigation	investigation	NOUN
bjp-61292	88	84	.	.	PUNCT
bjp-61292	89	1	compared	compare	VERB
bjp-61292	89	2	to	to	ADP
bjp-61292	89	3	mda	mda	PROPN
bjp-61292	89	4	-	-	PUNCT
bjp-61292	89	5	mb453	mb453	PROPN
bjp-61292	89	6	cells	cell	NOUN
bjp-61292	89	7	,	,	PUNCT
bjp-61292	89	8	significantly	significantly	ADV
bjp-61292	89	9	higher	high	ADJ
bjp-61292	89	10	wound	wound	NOUN
bjp-61292	89	11	width	width	NOUN
bjp-61292	89	12	(	(	PUNCT
bjp-61292	89	13	figure	figure	NOUN
bjp-61292	89	14	1a	1a	NOUN
bjp-61292	89	15	)	)	PUNCT
bjp-61292	89	16	and	and	CCONJ
bjp-61292	89	17	number	number	NOUN
bjp-61292	89	18	of	of	ADP
bjp-61292	89	19	migrated	migrate	VERB
bjp-61292	89	20	cells	cell	NOUN
bjp-61292	89	21	(	(	PUNCT
bjp-61292	89	22	figure	figure	NOUN
bjp-61292	89	23	1b	1b	NUM
bjp-61292	89	24	)	)	PUNCT
bjp-61292	89	25	were	be	AUX
bjp-61292	89	26	observed	observe	VERB
bjp-61292	89	27	in	in	ADP
bjp-61292	89	28	mda	mda	PROPN
bjp-61292	89	29	-	-	PUNCT
bjp-61292	89	30	mb-231	mb-231	PROPN
bjp-61292	89	31	cells	cell	NOUN
bjp-61292	89	32	(	(	PUNCT
bjp-61292	89	33	p<0.01	p<0.01	PROPN
bjp-61292	89	34	)	)	PUNCT
bjp-61292	89	35	.	.	PUNCT
bjp-61292	90	1	the	the	DET
bjp-61292	90	2	expression	expression	NOUN
bjp-61292	90	3	level	level	NOUN
bjp-61292	90	4	of	of	ADP
bjp-61292	90	5	dkk1	dkk1	PROPN
bjp-61292	90	6	in	in	ADP
bjp-61292	90	7	mda	mda	PROPN
bjp-61292	90	8	-	-	PUNCT
bjp-61292	90	9	mb-231	mb-231	PROPN
bjp-61292	90	10	cells	cell	NOUN
bjp-61292	90	11	was	be	AUX
bjp-61292	90	12	greatly	greatly	ADV
bjp-61292	90	13	higher	high	ADJ
bjp-61292	90	14	than	than	ADP
bjp-61292	90	15	the	the	DET
bjp-61292	90	16	expression	expression	NOUN
bjp-61292	90	17	level	level	NOUN
bjp-61292	90	18	of	of	ADP
bjp-61292	90	19	dkk1	dkk1	PROPN
bjp-61292	90	20	in	in	ADP
bjp-61292	90	21	mda	mda	PROPN
bjp-61292	90	22	-	-	PUNCT
bjp-61292	90	23	mb-453	mb-453	NOUN
bjp-61292	90	24	cells	cell	NOUN
bjp-61292	90	25	(	(	PUNCT
bjp-61292	90	26	p<0.01	p<0.01	PROPN
bjp-61292	90	27	)	)	PUNCT
bjp-61292	90	28	.	.	PUNCT
bjp-61292	91	1	zoledronic	zoledronic	ADJ
bjp-61292	91	2	acid	acid	PROPN
bjp-61292	91	3	is	be	AUX
bjp-61292	91	4	reported	report	VERB
bjp-61292	91	5	to	to	PART
bjp-61292	91	6	suppress	suppress	VERB
bjp-61292	91	7	the	the	DET
bjp-61292	91	8	activity	activity	NOUN
bjp-61292	91	9	of	of	ADP
bjp-61292	91	10	osteoclasts	osteoclast	NOUN
bjp-61292	91	11	by	by	ADP
bjp-61292	91	12	downregulating	downregulating	NOUN
bjp-61292	91	13	dkk1	dkk1	PROPN
bjp-61292	91	14	(	(	PUNCT
bjp-61292	91	15	polyzos	polyzos	PROPN
bjp-61292	91	16	et	et	PROPN
bjp-61292	91	17	al	al	PROPN
bjp-61292	91	18	.	.	PROPN
bjp-61292	91	19	,	,	PUNCT
bjp-61292	91	20	2009	2009	NUM
bjp-61292	91	21	;	;	PUNCT
bjp-61292	91	22	gobel	gobel	NOUN
bjp-61292	91	23	et	et	PROPN
bjp-61292	91	24	al	al	PROPN
bjp-61292	91	25	.	.	PROPN
bjp-61292	91	26	,	,	PUNCT
bjp-61292	91	27	2015	2015	NUM
bjp-61292	91	28	)	)	PUNCT
bjp-61292	91	29	.	.	PUNCT
bjp-61292	92	1	to	to	PART
bjp-61292	92	2	verify	verify	VERB
bjp-61292	92	3	the	the	DET
bjp-61292	92	4	effects	effect	NOUN
bjp-61292	92	5	of	of	ADP
bjp-61292	92	6	za	za	PROPN
bjp-61292	92	7	,	,	PUNCT
bjp-61292	92	8	mda	mda	PROPN
bjp-61292	92	9	-	-	PUNCT
bjp-61292	92	10	mb-231	mb-231	PROPN
bjp-61292	92	11	cells	cell	NOUN
bjp-61292	92	12	were	be	AUX
bjp-61292	92	13	incubated	incubate	VERB
bjp-61292	92	14	with	with	ADP
bjp-61292	92	15	different	different	ADJ
bjp-61292	92	16	concentrations	concentration	NOUN
bjp-61292	92	17	of	of	ADP
bjp-61292	92	18	zoledronic	zoledronic	ADJ
bjp-61292	92	19	acid	acid	NOUN
bjp-61292	92	20	(	(	PUNCT
bjp-61292	92	21	0	0	NUM
bjp-61292	92	22	,	,	PUNCT
bjp-61292	92	23	25	25	NUM
bjp-61292	92	24	,	,	PUNCT
bjp-61292	92	25	50	50	NUM
bjp-61292	92	26	,	,	PUNCT
bjp-61292	92	27	100	100	NUM
bjp-61292	92	28	,	,	PUNCT
bjp-61292	92	29	and	and	CCONJ
bjp-61292	92	30	200	200	NUM
bjp-61292	92	31	μm	μm	NUM
bjp-61292	92	32	)	)	PUNCT
bjp-61292	92	33	,	,	PUNCT
bjp-61292	92	34	followed	follow	VERB
bjp-61292	92	35	by	by	ADP
bjp-61292	92	36	determining	determine	VERB
bjp-61292	92	37	the	the	DET
bjp-61292	92	38	expression	expression	NOUN
bjp-61292	92	39	level	level	NOUN
bjp-61292	92	40	of	of	ADP
bjp-61292	92	41	dkk1	dkk1	PROPN
bjp-61292	92	42	and	and	CCONJ
bjp-61292	92	43	extracting	extract	VERB
bjp-61292	92	44	exosomes	exosome	NOUN
bjp-61292	92	45	.	.	PUNCT
bjp-61292	93	1	we	we	PRON
bjp-61292	93	2	found	find	VERB
bjp-61292	93	3	that	that	SCONJ
bjp-61292	93	4	dkk1	dkk1	PROPN
bjp-61292	93	5	was	be	AUX
bjp-61292	93	6	dramatically	dramatically	ADV
bjp-61292	93	7	downregulated	downregulate	VERB
bjp-61292	93	8	by	by	ADP
bjp-61292	93	9	the	the	DET
bjp-61292	93	10	treatment	treatment	NOUN
bjp-61292	93	11	of	of	ADP
bjp-61292	93	12	zoledronic	zoledronic	ADJ
bjp-61292	93	13	acid	acid	NOUN
bjp-61292	93	14	(	(	PUNCT
bjp-61292	93	15	p<0.05	p<0.05	PROPN
bjp-61292	93	16	,	,	PUNCT
bjp-61292	93	17	p<0.01	p<0.01	PROPN
bjp-61292	93	18	)	)	PUNCT
bjp-61292	93	19	.	.	PUNCT
bjp-61292	94	1	exosomes	exosome	NOUN
bjp-61292	94	2	extracted	extract	VERB
bjp-61292	94	3	from	from	ADP
bjp-61292	94	4	mda	mda	PROPN
bjp-61292	94	5	-	-	PUNCT
bjp-61292	94	6	mb-231	mb-231	PROPN
bjp-61292	94	7	cells	cell	NOUN
bjp-61292	94	8	treated	treat	VERB
bjp-61292	94	9	with	with	ADP
bjp-61292	94	10	different	different	ADJ
bjp-61292	94	11	concentrations	concentration	NOUN
bjp-61292	94	12	of	of	ADP
bjp-61292	94	13	zoledronic	zoledronic	ADJ
bjp-61292	94	14	acid	acid	NOUN
bjp-61292	94	15	were	be	AUX
bjp-61292	94	16	identified	identify	VERB
bjp-61292	94	17	by	by	ADP
bjp-61292	94	18	tem	tem	PROPN
bjp-61292	94	19	(	(	PUNCT
bjp-61292	94	20	figure	figure	NOUN
bjp-61292	94	21	1f	1f	NUM
bjp-61292	94	22	)	)	PUNCT
bjp-61292	94	23	and	and	CCONJ
bjp-61292	94	24	determining	determine	VERB
bjp-61292	94	25	the	the	DET
bjp-61292	94	26	expression	expression	NOUN
bjp-61292	94	27	level	level	NOUN
bjp-61292	94	28	of	of	ADP
bjp-61292	94	29	cd63	cd63	PROPN
bjp-61292	94	30	and	and	CCONJ
bjp-61292	94	31	cd81	cd81	PROPN
bjp-61292	94	32	(	(	PUNCT
bjp-61292	94	33	fig	fig	NOUN
bjp-61292	94	34	1	1	NUM
bjp-61292	94	35	g	g	NOUN
bjp-61292	94	36	)	)	PUNCT
bjp-61292	94	37	.	.	PUNCT
bjp-61292	95	1	subsequently	subsequently	ADV
bjp-61292	95	2	,	,	PUNCT
bjp-61292	95	3	the	the	DET
bjp-61292	95	4	expression	expression	NOUN
bjp-61292	95	5	level	level	NOUN
bjp-61292	95	6	of	of	ADP
bjp-61292	95	7	dkk1	dkk1	PROPN
bjp-61292	95	8	in	in	ADP
bjp-61292	95	9	mdamb-231	mdamb-231	ADJ
bjp-61292	95	10	exosomes	exosome	NOUN
bjp-61292	95	11	was	be	AUX
bjp-61292	95	12	evaluated	evaluate	VERB
bjp-61292	95	13	.	.	PUNCT
bjp-61292	96	1	similar	similar	ADJ
bjp-61292	96	2	to	to	ADP
bjp-61292	96	3	parent	parent	NOUN
bjp-61292	96	4	cells	cell	NOUN
bjp-61292	96	5	,	,	PUNCT
bjp-61292	96	6	dkk1	dkk1	PROPN
bjp-61292	96	7	in	in	ADP
bjp-61292	96	8	mda	mda	PROPN
bjp-61292	96	9	-	-	PUNCT
bjp-61292	96	10	mb-231	mb-231	PROPN
bjp-61292	96	11	exosomes	exosome	NOUN
bjp-61292	96	12	(	(	PUNCT
bjp-61292	96	13	figure	figure	VERB
bjp-61292	96	14	1h	1h	NUM
bjp-61292	96	15	-	-	PUNCT
bjp-61292	96	16	i	i	PROPN
bjp-61292	96	17	)	)	PUNCT
bjp-61292	96	18	was	be	AUX
bjp-61292	96	19	significantly	significantly	ADV
bjp-61292	96	20	down	down	ADV
bjp-61292	96	21	-	-	PUNCT
bjp-61292	96	22	regulated	regulate	VERB
bjp-61292	96	23	by	by	ADP
bjp-61292	96	24	the	the	DET
bjp-61292	96	25	treatment	treatment	NOUN
bjp-61292	96	26	of	of	ADP
bjp-61292	96	27	zoledronic	zoledronic	ADJ
bjp-61292	96	28	acid	acid	NOUN
bjp-61292	96	29	(	(	PUNCT
bjp-61292	96	30	p<0.05	p<0.05	PROPN
bjp-61292	96	31	,	,	PUNCT
bjp-61292	96	32	p<0.01	p<0.01	PROPN
bjp-61292	96	33	)	)	PUNCT
bjp-61292	96	34	.	.	PUNCT
bjp-61292	97	1	to	to	PART
bjp-61292	97	2	further	far	ADV
bjp-61292	97	3	verify	verify	VERB
bjp-61292	97	4	the	the	DET
bjp-61292	97	5	consistency	consistency	NOUN
bjp-61292	97	6	between	between	ADP
bjp-61292	97	7	parent	parent	NOUN
bjp-61292	97	8	cells	cell	NOUN
bjp-61292	97	9	and	and	CCONJ
bjp-61292	97	10	exosomes	exosome	NOUN
bjp-61292	97	11	on	on	ADP
bjp-61292	97	12	the	the	DET
bjp-61292	97	13	expression	expression	NOUN
bjp-61292	97	14	level	level	NOUN
bjp-61292	97	15	of	of	ADP
bjp-61292	97	16	dkk1	dkk1	PROPN
bjp-61292	97	17	,	,	PUNCT
bjp-61292	97	18	dkk1	dkk1	PROPN
bjp-61292	97	19	overexpressed	overexpresse	VERB
bjp-61292	97	20	mdamb-231	mdamb-231	ADJ
bjp-61292	97	21	cells	cell	NOUN
bjp-61292	97	22	and	and	CCONJ
bjp-61292	97	23	mda	mda	PROPN
bjp-61292	97	24	-	-	PUNCT
bjp-61292	97	25	mb-453	mb-453	NUM
bjp-61292	97	26	cells	cell	NOUN
bjp-61292	97	27	were	be	AUX
bjp-61292	97	28	established	establish	VERB
bjp-61292	97	29	.	.	PUNCT
bjp-61292	98	1	the	the	DET
bjp-61292	98	2	transfection	transfection	NOUN
bjp-61292	98	3	efficacy	efficacy	NOUN
bjp-61292	98	4	was	be	AUX
bjp-61292	98	5	first	first	ADV
bjp-61292	98	6	identified	identify	VERB
bjp-61292	98	7	using	use	VERB
bjp-61292	98	8	the	the	DET
bjp-61292	98	9	pcr	pcr	NOUN
bjp-61292	98	10	(	(	PUNCT
bjp-61292	98	11	p<0.01	p<0.01	PROPN
bjp-61292	98	12	)	)	PUNCT
bjp-61292	98	13	and	and	CCONJ
bjp-61292	98	14	western	western	ADJ
bjp-61292	98	15	blotting	blot	VERB
bjp-61292	98	16	assay	assay	NOUN
bjp-61292	98	17	(	(	PUNCT
bjp-61292	98	18	figure	figure	NOUN
bjp-61292	98	19	1j	1j	NUM
bjp-61292	98	20	)	)	PUNCT
bjp-61292	98	21	.	.	PUNCT
bjp-61292	99	1	exosomes	exosome	NOUN
bjp-61292	99	2	extracted	extract	VERB
bjp-61292	99	3	from	from	ADP
bjp-61292	99	4	cells	cell	NOUN
bjp-61292	99	5	were	be	AUX
bjp-61292	99	6	identified	identify	VERB
bjp-61292	99	7	by	by	ADP
bjp-61292	99	8	tem	tem	PROPN
bjp-61292	99	9	(	(	PUNCT
bjp-61292	99	10	figure	figure	NOUN
bjp-61292	99	11	1k	1k	NUM
bjp-61292	99	12	)	)	PUNCT
bjp-61292	99	13	and	and	CCONJ
bjp-61292	99	14	determining	determine	VERB
bjp-61292	99	15	the	the	DET
bjp-61292	99	16	expression	expression	NOUN
bjp-61292	99	17	level	level	NOUN
bjp-61292	99	18	of	of	ADP
bjp-61292	99	19	cd63	cd63	PROPN
bjp-61292	99	20	and	and	CCONJ
bjp-61292	99	21	cd81	cd81	PROPN
bjp-61292	99	22	(	(	PUNCT
bjp-61292	99	23	figure	figure	NOUN
bjp-61292	99	24	1l	1l	NUM
bjp-61292	99	25	)	)	PUNCT
bjp-61292	99	26	.	.	PUNCT
bjp-61292	100	1	compared	compare	VERB
bjp-61292	100	2	to	to	ADP
bjp-61292	100	3	the	the	DET
bjp-61292	100	4	blank	blank	ADJ
bjp-61292	100	5	vector	vector	NOUN
bjp-61292	100	6	,	,	PUNCT
bjp-61292	100	7	the	the	DET
bjp-61292	100	8	expression	expression	NOUN
bjp-61292	100	9	level	level	NOUN
bjp-61292	100	10	of	of	ADP
bjp-61292	100	11	dkk1	dkk1	PROPN
bjp-61292	100	12	in	in	ADP
bjp-61292	100	13	exosomes	exosome	NOUN
bjp-61292	100	14	extracted	extract	VERB
bjp-61292	100	15	from	from	ADP
bjp-61292	100	16	dkk1	dkk1	PROPN
bjp-61292	100	17	-	-	PUNCT
bjp-61292	100	18	overexpressed	overexpresse	VERB
bjp-61292	100	19	mda	mda	PROPN
bjp-61292	100	20	-	-	PUNCT
bjp-61292	100	21	mb-231	mb-231	PROPN
bjp-61292	100	22	cells	cell	NOUN
bjp-61292	100	23	or	or	CCONJ
bjp-61292	100	24	mda	mda	PROPN
bjp-61292	100	25	-	-	PUNCT
bjp-61292	100	26	mb-453	mb-453	NOUN
bjp-61292	100	27	cells	cell	NOUN
bjp-61292	100	28	was	be	AUX
bjp-61292	100	29	much	much	ADV
bjp-61292	100	30	higher	high	ADJ
bjp-61292	100	31	(	(	PUNCT
bjp-61292	100	32	p<0.01	p<0.01	PROPN
bjp-61292	100	33	)	)	PUNCT
bjp-61292	100	34	.	.	PUNCT
bjp-61292	101	1	these	these	DET
bjp-61292	101	2	data	datum	NOUN
bjp-61292	101	3	revealed	reveal	VERB
bjp-61292	101	4	that	that	SCONJ
bjp-61292	101	5	dkk1	dkk1	PROPN
bjp-61292	101	6	could	could	AUX
bjp-61292	101	7	be	be	AUX
bjp-61292	101	8	delivered	deliver	VERB
bjp-61292	101	9	by	by	ADP
bjp-61292	101	10	exosomes	exosome	NOUN
bjp-61292	101	11	extracted	extract	VERB
bjp-61292	101	12	from	from	ADP
bjp-61292	101	13	breast	breast	NOUN
bjp-61292	101	14	cancer	cancer	NOUN
bjp-61292	101	15	cells	cell	NOUN
bjp-61292	101	16	.	.	PUNCT
bjp-61292	102	1	exosomes	exosome	NOUN
bjp-61292	102	2	derived	derive	VERB
bjp-61292	102	3	from	from	ADP
bjp-61292	102	4	zoledronic	zoledronic	ADJ
bjp-61292	102	5	acid	acid	NOUN
bjp-61292	102	6	-	-	PUNCT
bjp-61292	102	7	treated	treat	VERB
bjp-61292	102	8	mdamb-453	mdamb-453	NOUN
bjp-61292	102	9	cells	cell	NOUN
bjp-61292	102	10	suppressed	suppress	VERB
bjp-61292	102	11	the	the	DET
bjp-61292	102	12	migration	migration	NOUN
bjp-61292	102	13	of	of	ADP
bjp-61292	102	14	breast	breast	NOUN
bjp-61292	102	15	cancer	cancer	NOUN
bjp-61292	102	16	cells	cell	NOUN
bjp-61292	102	17	to	to	PART
bjp-61292	102	18	explore	explore	VERB
bjp-61292	102	19	whether	whether	SCONJ
bjp-61292	102	20	zoledronic	zoledronic	ADJ
bjp-61292	102	21	acid	acid	NOUN
bjp-61292	102	22	impacted	impact	VERB
bjp-61292	102	23	the	the	DET
bjp-61292	102	24	migration	migration	NOUN
bjp-61292	102	25	of	of	ADP
bjp-61292	102	26	breast	breast	NOUN
bjp-61292	102	27	cancer	cancer	NOUN
bjp-61292	102	28	cells	cell	NOUN
bjp-61292	102	29	by	by	ADP
bjp-61292	102	30	acting	act	VERB
bjp-61292	102	31	on	on	ADP
bjp-61292	102	32	tumor	tumor	NOUN
bjp-61292	102	33	cell	cell	NOUN
bjp-61292	102	34	decried	decry	VERB
bjp-61292	102	35	exosomes	exosome	NOUN
bjp-61292	102	36	,	,	PUNCT
bjp-61292	102	37	mda	mda	NOUN
bjp-61292	102	38	-	-	PUNCT
bjp-61292	102	39	mb-453	mb-453	NUM
bjp-61292	102	40	cells	cell	NOUN
bjp-61292	102	41	were	be	AUX
bjp-61292	102	42	incubated	incubate	VERB
bjp-61292	102	43	with	with	ADP
bjp-61292	102	44	exosomes	exosome	NOUN
bjp-61292	102	45	extracted	extract	VERB
bjp-61292	102	46	from	from	ADP
bjp-61292	102	47	mda	mda	PROPN
bjp-61292	102	48	-	-	PUNCT
bjp-61292	102	49	mb-453	mb-453	NOUN
bjp-61292	102	50	cells	cell	NOUN
bjp-61292	102	51	treated	treat	VERB
bjp-61292	102	52	by	by	ADP
bjp-61292	102	53	200	200	NUM
bjp-61292	102	54	μm	μm	ADJ
bjp-61292	102	55	zoledronic	zoledronic	ADJ
bjp-61292	102	56	acid	acid	NOUN
bjp-61292	102	57	or	or	CCONJ
bjp-61292	102	58	pbs	pbs	PROPN
bjp-61292	102	59	buffer	buffer	NOUN
bjp-61292	102	60	.	.	PUNCT
bjp-61292	103	1	we	we	PRON
bjp-61292	103	2	found	find	VERB
bjp-61292	103	3	that	that	SCONJ
bjp-61292	103	4	compared	compare	VERB
bjp-61292	103	5	to	to	ADP
bjp-61292	103	6	pbs	pbs	PROPN
bjp-61292	103	7	,	,	PUNCT
bjp-61292	103	8	significantly	significantly	ADV
bjp-61292	103	9	lower	low	ADJ
bjp-61292	103	10	cell	cell	NOUN
bjp-61292	103	11	viability	viability	NOUN
bjp-61292	103	12	(	(	PUNCT
bjp-61292	103	13	figure	figure	NOUN
bjp-61292	103	14	2a	2a	NUM
bjp-61292	103	15	)	)	PUNCT
bjp-61292	103	16	,	,	PUNCT
bjp-61292	103	17	a	a	DET
bjp-61292	103	18	smaller	small	ADJ
bjp-61292	103	19	number	number	NOUN
bjp-61292	103	20	of	of	ADP
bjp-61292	103	21	colonies	colony	NOUN
bjp-61292	103	22	(	(	PUNCT
bjp-61292	103	23	figure	figure	NOUN
bjp-61292	103	24	2b	2b	NOUN
bjp-61292	103	25	)	)	PUNCT
bjp-61292	103	26	and	and	CCONJ
bjp-61292	103	27	migrated	migrate	VERB
bjp-61292	103	28	cells	cell	NOUN
bjp-61292	103	29	(	(	PUNCT
bjp-61292	103	30	figure	figure	NOUN
bjp-61292	103	31	2c	2c	NUM
bjp-61292	103	32	)	)	PUNCT
bjp-61292	103	33	,	,	PUNCT
bjp-61292	103	34	and	and	CCONJ
bjp-61292	103	35	larger	large	ADJ
bjp-61292	103	36	wound	wound	NOUN
bjp-61292	103	37	width	width	NOUN
bjp-61292	103	38	(	(	PUNCT
bjp-61292	103	39	figure	figure	NOUN
bjp-61292	103	40	2d	2d	NOUN
bjp-61292	103	41	)	)	PUNCT
bjp-61292	103	42	were	be	AUX
bjp-61292	103	43	observed	observe	VERB
bjp-61292	103	44	in	in	ADP
bjp-61292	103	45	mda	mda	PROPN
bjp-61292	103	46	-	-	PUNCT
bjp-61292	103	47	mb453	mb453	PROPN
bjp-61292	103	48	cells	cell	NOUN
bjp-61292	103	49	by	by	ADP
bjp-61292	103	50	the	the	DET
bjp-61292	103	51	treatment	treatment	NOUN
bjp-61292	103	52	of	of	ADP
bjp-61292	103	53	200	200	NUM
bjp-61292	103	54	μm	μm	NUM
bjp-61292	103	55	zoledronic	zoledronic	ADJ
bjp-61292	103	56	acidincubated	acidincubate	VERB
bjp-61292	103	57	mda	mda	PROPN
bjp-61292	103	58	-	-	PUNCT
bjp-61292	103	59	mb-453	mb-453	NOUN
bjp-61292	103	60	cells	cell	NOUN
bjp-61292	103	61	-	-	PUNCT
bjp-61292	103	62	derived	derive	VERB
bjp-61292	103	63	exosomes	exosome	NOUN
bjp-61292	103	64	(	(	PUNCT
bjp-61292	103	65	p<0.05	p<0.05	NOUN
bjp-61292	103	66	,	,	PUNCT
bjp-61292	103	67	p<0.01	p<0.01	PROPN
bjp-61292	103	68	)	)	PUNCT
bjp-61292	103	69	.	.	PUNCT
bjp-61292	104	1	these	these	DET
bjp-61292	104	2	results	result	NOUN
bjp-61292	104	3	revealed	reveal	VERB
bjp-61292	104	4	that	that	SCONJ
bjp-61292	104	5	the	the	DET
bjp-61292	104	6	migration	migration	NOUN
bjp-61292	104	7	of	of	ADP
bjp-61292	104	8	breast	breast	NOUN
bjp-61292	104	9	cancer	cancer	NOUN
bjp-61292	104	10	cells	cell	NOUN
bjp-61292	104	11	was	be	AUX
bjp-61292	104	12	dramatically	dramatically	ADV
bjp-61292	104	13	repressed	repress	VERB
bjp-61292	104	14	by	by	ADP
bjp-61292	104	15	zoledronic	zoledronic	ADJ
bjp-61292	104	16	acid	acid	NOUN
bjp-61292	104	17	-	-	PUNCT
bjp-61292	104	18	treated	treat	VERB
bjp-61292	104	19	mda	mda	PROPN
bjp-61292	104	20	-	-	PUNCT
bjp-61292	104	21	mb-453	mb-453	NOUN
bjp-61292	104	22	cells	cell	NOUN
bjp-61292	104	23	-	-	PUNCT
bjp-61292	104	24	derived	derive	VERB
bjp-61292	104	25	exosomes	exosome	NOUN
bjp-61292	104	26	.	.	PUNCT
bjp-61292	105	1	exosomes	exosome	NOUN
bjp-61292	105	2	derived	derive	VERB
bjp-61292	105	3	from	from	ADP
bjp-61292	105	4	zoledronic	zoledronic	ADJ
bjp-61292	105	5	acid	acid	NOUN
bjp-61292	105	6	-	-	PUNCT
bjp-61292	105	7	treated	treat	VERB
bjp-61292	105	8	mdamb-453	mdamb-453	NOUN
bjp-61292	105	9	cells	cell	NOUN
bjp-61292	105	10	inhibited	inhibit	VERB
bjp-61292	105	11	the	the	DET
bjp-61292	105	12	differentiation	differentiation	NOUN
bjp-61292	105	13	and	and	CCONJ
bjp-61292	105	14	maturity	maturity	NOUN
bjp-61292	105	15	of	of	ADP
bjp-61292	105	16	osteoclasts	osteoclast	NOUN
bjp-61292	105	17	firstly	firstly	ADV
bjp-61292	105	18	,	,	PUNCT
bjp-61292	105	19	the	the	DET
bjp-61292	105	20	trap	trap	NOUN
bjp-61292	105	21	staining	stain	VERB
bjp-61292	105	22	assay	assay	NOUN
bjp-61292	105	23	was	be	AUX
bjp-61292	105	24	conducted	conduct	VERB
bjp-61292	105	25	to	to	PART
bjp-61292	105	26	evaluate	evaluate	VERB
bjp-61292	105	27	the	the	DET
bjp-61292	105	28	activity	activity	NOUN
bjp-61292	105	29	of	of	ADP
bjp-61292	105	30	bone	bone	NOUN
bjp-61292	105	31	resorption	resorption	NOUN
bjp-61292	105	32	in	in	ADP
bjp-61292	105	33	osteoclasts	osteoclast	NOUN
bjp-61292	105	34	.	.	PUNCT
bjp-61292	106	1	compared	compare	VERB
bjp-61292	106	2	to	to	ADP
bjp-61292	106	3	pbs	pbs	PROPN
bjp-61292	106	4	,	,	PUNCT
bjp-61292	106	5	a	a	DET
bjp-61292	106	6	significant	significant	ADJ
bjp-61292	106	7	more	more	ADV
bjp-61292	106	8	trap	trap	NOUN
bjp-61292	106	9	-	-	PUNCT
bjp-61292	106	10	positive	positive	ADJ
bjp-61292	106	11	cell	cell	NOUN
bjp-61292	106	12	number	number	NOUN
bjp-61292	106	13	(	(	PUNCT
bjp-61292	106	14	figure	figure	NOUN
bjp-61292	106	15	3a	3a	NUM
bjp-61292	106	16	,	,	PUNCT
bjp-61292	106	17	c	c	NOUN
bjp-61292	106	18	)	)	PUNCT
bjp-61292	106	19	was	be	AUX
bjp-61292	106	20	observed	observe	VERB
bjp-61292	106	21	in	in	ADP
bjp-61292	106	22	raw	raw	ADJ
bjp-61292	106	23	264.7	264.7	NUM
bjp-61292	106	24	cells	cell	NOUN
bjp-61292	106	25	by	by	ADP
bjp-61292	106	26	the	the	DET
bjp-61292	106	27	treatment	treatment	NOUN
bjp-61292	106	28	exosomes	exosome	NOUN
bjp-61292	106	29	derived	derive	VERB
bjp-61292	106	30	from	from	ADP
bjp-61292	106	31	200	200	NUM
bjp-61292	106	32	μm	μm	NUM
bjp-61292	106	33	zoledronic	zoledronic	ADJ
bjp-61292	106	34	acid	acid	NOUN
bjp-61292	106	35	-	-	PUNCT
bjp-61292	106	36	treated	treat	VERB
bjp-61292	106	37	mda	mda	PROPN
bjp-61292	106	38	-	-	PUNCT
bjp-61292	106	39	mb-453	mb-453	NOUN
bjp-61292	106	40	cells	cell	NOUN
bjp-61292	106	41	(	(	PUNCT
bjp-61292	106	42	p<0.01	p<0.01	PROPN
bjp-61292	106	43	)	)	PUNCT
bjp-61292	106	44	.	.	PUNCT
bjp-61292	107	1	to	to	PART
bjp-61292	107	2	identify	identify	VERB
bjp-61292	107	3	osteoclasts	osteoclast	NOUN
bjp-61292	107	4	and	and	CCONJ
bjp-61292	107	5	trace	trace	VERB
bjp-61292	107	6	the	the	DET
bjp-61292	107	7	location	location	NOUN
bjp-61292	107	8	of	of	ADP
bjp-61292	107	9	exosomes	exosome	NOUN
bjp-61292	107	10	in	in	ADP
bjp-61292	107	11	raw	raw	ADJ
bjp-61292	107	12	264.7	264.7	NUM
bjp-61292	107	13	cells	cell	NOUN
bjp-61292	107	14	,	,	PUNCT
bjp-61292	107	15	the	the	DET
bjp-61292	107	16	immunostaining	immunostaine	VERB
bjp-61292	107	17	assay	assay	NOUN
bjp-61292	107	18	on	on	ADP
bjp-61292	107	19	phalloidine	phalloidine	PROPN
bjp-61292	107	20	and	and	CCONJ
bjp-61292	107	21	pkh67	pkh67	PROPN
bjp-61292	107	22	was	be	AUX
bjp-61292	107	23	conducted	conduct	VERB
bjp-61292	107	24	.	.	PUNCT
bjp-61292	108	1	as	as	SCONJ
bjp-61292	108	2	shown	show	VERB
bjp-61292	108	3	in	in	ADP
bjp-61292	108	4	figure	figure	NOUN
bjp-61292	108	5	3b	3b	NUM
bjp-61292	108	6	,	,	PUNCT
bjp-61292	108	7	compared	compare	VERB
bjp-61292	108	8	to	to	ADP
bjp-61292	108	9	pbs	pbs	PROPN
bjp-61292	108	10	,	,	PUNCT
bjp-61292	108	11	a	a	DET
bjp-61292	108	12	lower	low	ADJ
bjp-61292	108	13	expression	expression	NOUN
bjp-61292	108	14	level	level	NOUN
bjp-61292	108	15	of	of	ADP
bjp-61292	108	16	phalloidine	phalloidine	NOUN
bjp-61292	108	17	was	be	AUX
bjp-61292	108	18	observed	observe	VERB
bjp-61292	108	19	in	in	ADP
bjp-61292	108	20	raw	raw	ADJ
bjp-61292	108	21	264.7	264.7	NUM
bjp-61292	108	22	cells	cell	NOUN
bjp-61292	108	23	incubated	incubate	VERB
bjp-61292	108	24	with	with	ADP
bjp-61292	108	25	exosomes	exosome	NOUN
bjp-61292	108	26	derived	derive	VERB
bjp-61292	108	27	from	from	ADP
bjp-61292	108	28	200	200	NUM
bjp-61292	108	29	μm	μm	NOUN
bjp-61292	108	30	zoledronic	zoledronic	NOUN
bjp-61292	108	31	acidtreated	acidtreate	VERB
bjp-61292	108	32	mda	mda	PROPN
bjp-61292	108	33	-	-	PUNCT
bjp-61292	108	34	mb-453	mb-453	NUM
bjp-61292	108	35	cells	cell	NOUN
bjp-61292	108	36	,	,	PUNCT
bjp-61292	108	37	accompanied	accompany	VERB
bjp-61292	108	38	by	by	ADP
bjp-61292	108	39	downregulated	downregulate	VERB
bjp-61292	108	40	pkh67	pkh67	PROPN
bjp-61292	108	41	.	.	PUNCT
bjp-61292	109	1	subsequently	subsequently	ADV
bjp-61292	109	2	,	,	PUNCT
bjp-61292	109	3	the	the	DET
bjp-61292	109	4	expression	expression	NOUN
bjp-61292	109	5	level	level	NOUN
bjp-61292	109	6	of	of	ADP
bjp-61292	109	7	biomarkers	biomarker	NOUN
bjp-61292	109	8	of	of	ADP
bjp-61292	109	9	mature	mature	ADJ
bjp-61292	109	10	osteoclasts	osteoclast	NOUN
bjp-61292	109	11	was	be	AUX
bjp-61292	109	12	further	far	ADV
bjp-61292	109	13	determined	determine	VERB
bjp-61292	109	14	.	.	PUNCT
bjp-61292	110	1	we	we	PRON
bjp-61292	110	2	found	find	VERB
bjp-61292	110	3	that	that	SCONJ
bjp-61292	110	4	compared	compare	VERB
bjp-61292	110	5	to	to	ADP
bjp-61292	110	6	pbs	pbs	PROPN
bjp-61292	110	7	,	,	PUNCT
bjp-61292	110	8	trap	trap	NOUN
bjp-61292	110	9	,	,	PUNCT
bjp-61292	110	10	oscar	oscar	NOUN
bjp-61292	110	11	,	,	PUNCT
bjp-61292	110	12	c	c	NOUN
bjp-61292	110	13	-	-	PUNCT
bjp-61292	110	14	fos	fos	NOUN
bjp-61292	110	15	,	,	PUNCT
bjp-61292	110	16	and	and	CCONJ
bjp-61292	110	17	nfatc1	nfatc1	NOUN
bjp-61292	110	18	(	(	PUNCT
bjp-61292	110	19	figure	figure	NOUN
bjp-61292	110	20	3d	3d	NOUN
bjp-61292	110	21	-	-	PUNCT
bjp-61292	110	22	e	e	NOUN
bjp-61292	110	23	)	)	PUNCT
bjp-61292	110	24	were	be	AUX
bjp-61292	110	25	dramatically	dramatically	ADV
bjp-61292	110	26	down	down	ADV
bjp-61292	110	27	-	-	PUNCT
bjp-61292	110	28	regulated	regulate	VERB
bjp-61292	110	29	in	in	ADP
bjp-61292	110	30	raw	raw	ADJ
bjp-61292	110	31	264.7	264.7	NUM
bjp-61292	110	32	cells	cell	NOUN
bjp-61292	110	33	by	by	ADP
bjp-61292	110	34	the	the	DET
bjp-61292	110	35	treatment	treatment	NOUN
bjp-61292	110	36	exosomes	exosome	NOUN
bjp-61292	110	37	derived	derive	VERB
bjp-61292	110	38	from	from	ADP
bjp-61292	110	39	zoledronic	zoledronic	ADJ
bjp-61292	110	40	acidtreated	acidtreate	VERB
bjp-61292	110	41	mda	mda	PROPN
bjp-61292	110	42	-	-	PUNCT
bjp-61292	110	43	mb-453	mb-453	NOUN
bjp-61292	110	44	cells	cell	NOUN
bjp-61292	110	45	(	(	PUNCT
bjp-61292	110	46	p<0.01	p<0.01	PROPN
bjp-61292	110	47	)	)	PUNCT
bjp-61292	110	48	.	.	PUNCT
bjp-61292	111	1	in	in	ADP
bjp-61292	111	2	addition	addition	NOUN
bjp-61292	111	3	,	,	PUNCT
bjp-61292	111	4	the	the	DET
bjp-61292	111	5	concentration	concentration	NOUN
bjp-61292	111	6	of	of	ADP
bjp-61292	111	7	biochemical	biochemical	ADJ
bjp-61292	111	8	markers	marker	NOUN
bjp-61292	111	9	(	(	PUNCT
bjp-61292	111	10	figure	figure	NOUN
bjp-61292	111	11	3f	3f	PROPN
bjp-61292	111	12	-	-	PUNCT
bjp-61292	111	13	g	g	NOUN
bjp-61292	111	14	)	)	PUNCT
bjp-61292	111	15	of	of	ADP
bjp-61292	111	16	bone	bone	NOUN
bjp-61292	111	17	metabolism	metabolism	NOUN
bjp-61292	111	18	(	(	PUNCT
bjp-61292	111	19	ctx	ctx	NOUN
bjp-61292	111	20	and	and	CCONJ
bjp-61292	111	21	ntx	ntx	VERB
bjp-61292	111	22	)	)	PUNCT
bjp-61292	111	23	in	in	ADP
bjp-61292	111	24	raw	raw	ADJ
bjp-61292	111	25	264.7	264.7	NUM
bjp-61292	111	26	cells	cell	NOUN
bjp-61292	111	27	incubated	incubate	VERB
bjp-61292	111	28	with	with	ADP
bjp-61292	111	29	exosomes	exosome	NOUN
bjp-61292	111	30	derived	derive	VERB
bjp-61292	111	31	from	from	ADP
bjp-61292	111	32	zoledronic	zoledronic	ADJ
bjp-61292	111	33	acid	acid	NOUN
bjp-61292	111	34	treated	treat	VERB
bjp-61292	111	35	mda	mda	PROPN
bjp-61292	111	36	-	-	PUNCT
bjp-61292	111	37	mb-453	mb-453	NUM
bjp-61292	111	38	cells	cell	NOUN
bjp-61292	111	39	were	be	AUX
bjp-61292	111	40	greatly	greatly	ADV
bjp-61292	111	41	lower	low	ADJ
bjp-61292	111	42	than	than	ADP
bjp-61292	111	43	that	that	PRON
bjp-61292	111	44	in	in	ADP
bjp-61292	111	45	the	the	DET
bjp-61292	111	46	pbs	pbs	PROPN
bjp-61292	111	47	group	group	PROPN
bjp-61292	111	48	(	(	PUNCT
bjp-61292	111	49	p<0.01	p<0.01	PROPN
bjp-61292	111	50	)	)	PUNCT
bjp-61292	111	51	.	.	PUNCT
bjp-61292	112	1	lastly	lastly	ADV
bjp-61292	112	2	,	,	PUNCT
bjp-61292	112	3	compared	compare	VERB
bjp-61292	112	4	to	to	ADP
bjp-61292	112	5	pbs	pbs	PROPN
bjp-61292	112	6	,	,	PUNCT
bjp-61292	112	7	the	the	DET
bjp-61292	112	8	production	production	NOUN
bjp-61292	112	9	of	of	ADP
bjp-61292	112	10	tgf	tgf	PROPN
bjp-61292	112	11	-	-	PUNCT
bjp-61292	112	12	β	β	PROPN
bjp-61292	112	13	(	(	PUNCT
bjp-61292	112	14	figure	figure	NOUN
bjp-61292	112	15	3h	3h	NUM
bjp-61292	112	16	)	)	PUNCT
bjp-61292	112	17	was	be	AUX
bjp-61292	112	18	found	find	VERB
bjp-61292	112	19	to	to	PART
bjp-61292	112	20	decrease	decrease	VERB
bjp-61292	112	21	in	in	ADP
bjp-61292	112	22	raw	raw	ADJ
bjp-61292	112	23	264.7	264.7	NUM
bjp-61292	112	24	cells	cell	NOUN
bjp-61292	112	25	as	as	SCONJ
bjp-61292	112	26	time	time	NOUN
bjp-61292	112	27	went	go	VERB
bjp-61292	112	28	on	on	ADP
bjp-61292	112	29	by	by	ADP
bjp-61292	112	30	the	the	DET
bjp-61292	112	31	treatment	treatment	NOUN
bjp-61292	112	32	exosomes	exosome	NOUN
bjp-61292	112	33	derived	derive	VERB
bjp-61292	112	34	from	from	ADP
bjp-61292	112	35	zoledronic	zoledronic	ADJ
bjp-61292	112	36	acid	acid	NOUN
bjp-61292	112	37	-	-	PUNCT
bjp-61292	112	38	treated	treat	VERB
bjp-61292	112	39	mdamb-453	mdamb-453	NOUN
bjp-61292	112	40	cells	cell	NOUN
bjp-61292	112	41	(	(	PUNCT
bjp-61292	112	42	p<0.05	p<0.05	NOUN
bjp-61292	112	43	,	,	PUNCT
bjp-61292	112	44	p<0.01	p<0.01	PROPN
bjp-61292	112	45	)	)	PUNCT
bjp-61292	112	46	.	.	PUNCT
bjp-61292	113	1	these	these	DET
bjp-61292	113	2	results	result	NOUN
bjp-61292	113	3	revealed	reveal	VERB
bjp-61292	113	4	that	that	SCONJ
bjp-61292	113	5	differentiation	differentiation	NOUN
bjp-61292	113	6	and	and	CCONJ
bjp-61292	113	7	maturity	maturity	NOUN
bjp-61292	113	8	of	of	ADP
bjp-61292	113	9	osteoclasts	osteoclast	NOUN
bjp-61292	113	10	were	be	AUX
bjp-61292	113	11	drastically	drastically	ADV
bjp-61292	113	12	suppressed	suppress	VERB
bjp-61292	113	13	by	by	ADP
bjp-61292	113	14	exosomes	exosome	NOUN
bjp-61292	113	15	derived	derive	VERB
bjp-61292	113	16	from	from	ADP
bjp-61292	113	17	zoledronic	zoledronic	ADJ
bjp-61292	113	18	acid	acid	NOUN
bjp-61292	113	19	-	-	PUNCT
bjp-61292	113	20	treated	treat	VERB
bjp-61292	113	21	mda	mda	PROPN
bjp-61292	113	22	-	-	PUNCT
bjp-61292	113	23	mb-453	mb-453	NUM
bjp-61292	113	24	cells	cell	NOUN
bjp-61292	113	25	.	.	PUNCT
bjp-61292	114	1	effects	effect	NOUN
bjp-61292	114	2	of	of	ADP
bjp-61292	114	3	exosomes	exosome	NOUN
bjp-61292	114	4	-	-	PUNCT
bjp-61292	114	5	treated	treat	VERB
bjp-61292	114	6	raw	raw	ADJ
bjp-61292	114	7	264.7	264.7	NUM
bjp-61292	114	8	cells	cell	NOUN
bjp-61292	114	9	on	on	ADP
bjp-61292	114	10	the	the	DET
bjp-61292	114	11	proliferation	proliferation	NOUN
bjp-61292	114	12	and	and	CCONJ
bjp-61292	114	13	migration	migration	NOUN
bjp-61292	114	14	of	of	ADP
bjp-61292	114	15	breast	breast	NOUN
bjp-61292	114	16	cancer	cancer	NOUN
bjp-61292	114	17	cells	cell	NOUN
bjp-61292	114	18	to	to	PART
bjp-61292	114	19	further	far	ADV
bjp-61292	114	20	explore	explore	VERB
bjp-61292	114	21	the	the	DET
bjp-61292	114	22	interaction	interaction	NOUN
bjp-61292	114	23	between	between	ADP
bjp-61292	114	24	exosomes	exosome	NOUN
bjp-61292	114	25	treated	treat	VERB
bjp-61292	114	26	raw	raw	ADJ
bjp-61292	114	27	264.7	264.7	NUM
bjp-61292	114	28	cells	cell	NOUN
bjp-61292	114	29	and	and	CCONJ
bjp-61292	114	30	breast	breast	NOUN
bjp-61292	114	31	cancer	cancer	NOUN
bjp-61292	114	32	cells	cell	NOUN
bjp-61292	114	33	,	,	PUNCT
bjp-61292	114	34	the	the	DET
bjp-61292	114	35	proliferation	proliferation	NOUN
bjp-61292	114	36	and	and	CCONJ
bjp-61292	114	37	migration	migration	NOUN
bjp-61292	114	38	ability	ability	NOUN
bjp-61292	114	39	of	of	ADP
bjp-61292	114	40	mda	mda	PROPN
bjp-61292	114	41	-	-	PUNCT
bjp-61292	114	42	mb-453	mb-453	NOUN
bjp-61292	114	43	cells	cell	NOUN
bjp-61292	114	44	were	be	AUX
bjp-61292	114	45	evaluated	evaluate	VERB
bjp-61292	114	46	following	follow	VERB
bjp-61292	114	47	the	the	DET
bjp-61292	114	48	co	co	NOUN
bjp-61292	114	49	-	-	NOUN
bjp-61292	114	50	culture	culture	NOUN
bjp-61292	114	51	of	of	ADP
bjp-61292	114	52	exosomes	exosome	NOUN
bjp-61292	114	53	or	or	CCONJ
bjp-61292	114	54	pbs	pbs	PROPN
bjp-61292	114	55	-	-	PUNCT
bjp-61292	114	56	treated	treat	VERB
bjp-61292	114	57	raw	raw	ADJ
bjp-61292	114	58	264.7	264.7	NUM
bjp-61292	114	59	cells	cell	NOUN
bjp-61292	114	60	and	and	CCONJ
bjp-61292	114	61	mdamb-453	mdamb-453	ADJ
bjp-61292	114	62	cells	cell	NOUN
bjp-61292	114	63	.	.	PUNCT
bjp-61292	115	1	compared	compare	VERB
bjp-61292	115	2	to	to	ADP
bjp-61292	115	3	the	the	DET
bjp-61292	115	4	pbs	pbs	PROPN
bjp-61292	115	5	group	group	NOUN
bjp-61292	115	6	,	,	PUNCT
bjp-61292	115	7	significantly	significantly	ADV
bjp-61292	115	8	higher	high	ADJ
bjp-61292	115	9	cell	cell	NOUN
bjp-61292	115	10	viability	viability	NOUN
bjp-61292	115	11	(	(	PUNCT
bjp-61292	115	12	figure	figure	NOUN
bjp-61292	115	13	4a	4a	NUM
bjp-61292	115	14	)	)	PUNCT
bjp-61292	115	15	,	,	PUNCT
bjp-61292	115	16	a	a	DET
bjp-61292	115	17	greater	great	ADJ
bjp-61292	115	18	number	number	NOUN
bjp-61292	115	19	of	of	ADP
bjp-61292	115	20	colonies	colony	NOUN
bjp-61292	115	21	(	(	PUNCT
bjp-61292	115	22	figure	figure	VERB
bjp-61292	115	23	4b	4b	PROPN
bjp-61292	115	24	)	)	PUNCT
bjp-61292	115	25	and	and	CCONJ
bjp-61292	115	26	migrated	migrate	VERB
bjp-61292	115	27	cells	cell	NOUN
bjp-61292	115	28	(	(	PUNCT
bjp-61292	115	29	figure	figure	NOUN
bjp-61292	115	30	4d	4d	NUM
bjp-61292	115	31	)	)	PUNCT
bjp-61292	115	32	,	,	PUNCT
bjp-61292	115	33	and	and	CCONJ
bjp-61292	115	34	a	a	DET
bjp-61292	115	35	smaller	small	ADJ
bjp-61292	115	36	wound	wound	NOUN
bjp-61292	115	37	width	width	NOUN
bjp-61292	115	38	(	(	PUNCT
bjp-61292	115	39	figure	figure	NOUN
bjp-61292	115	40	4c	4c	NOUN
bjp-61292	115	41	)	)	PUNCT
bjp-61292	115	42	were	be	AUX
bjp-61292	115	43	found	find	VERB
bjp-61292	115	44	in	in	ADP
bjp-61292	115	45	mda	mda	PROPN
bjp-61292	115	46	-	-	PUNCT
bjp-61292	115	47	mb-453	mb-453	NOUN
bjp-61292	115	48	cells	cell	NOUN
bjp-61292	115	49	incubated	incubate	VERB
bjp-61292	115	50	with	with	ADP
bjp-61292	115	51	exosomes	exosome	NOUN
bjp-61292	115	52	derived	derive	VERB
bjp-61292	115	53	from	from	ADP
bjp-61292	115	54	mda	mda	PROPN
bjp-61292	115	55	-	-	PUNCT
bjp-61292	115	56	mb-453	mb-453	NUM
bjp-61292	115	57	cells	cell	NOUN
bjp-61292	115	58	.	.	PUNCT
bjp-61292	116	1	exosomes	exosome	NOUN
bjp-61292	116	2	derived	derive	VERB
bjp-61292	116	3	from	from	ADP
bjp-61292	116	4	zoledronic	zoledronic	ADJ
bjp-61292	116	5	acid	acid	NOUN
bjp-61292	116	6	-	-	PUNCT
bjp-61292	116	7	treated	treat	VERB
bjp-61292	116	8	mdamb-453	mdamb-453	NOUN
bjp-61292	116	9	cells	cell	NOUN
bjp-61292	116	10	suppressed	suppress	VERB
bjp-61292	116	11	the	the	DET
bjp-61292	116	12	emt	emt	PROPN
bjp-61292	116	13	progression	progression	NOUN
bjp-61292	116	14	and	and	CCONJ
bjp-61292	116	15	tgf	tgf	PROPN
bjp-61292	116	16	-β	-β	PUNCT
bjp-61292	116	17	signal	signal	PROPN
bjp-61292	116	18	pathway	pathway	NOUN
bjp-61292	116	19	bangladesh	bangladesh	PROPN
bjp-61292	116	20	j	j	PROPN
bjp-61292	116	21	pharmacol	pharmacol	PROPN
bjp-61292	116	22	2022	2022	NUM
bjp-61292	116	23	;	;	PUNCT
bjp-61292	116	24	17	17	NUM
bjp-61292	116	25	:	:	SYM
bjp-61292	116	26	92	92	NUM
bjp-61292	116	27	-	-	SYM
bjp-61292	116	28	101	101	NUM
bjp-61292	116	29	95	95	NUM
bjp-61292	116	30	figure	figure	NOUN
bjp-61292	116	31	1	1	NUM
bjp-61292	116	32	:	:	PUNCT
bjp-61292	116	33	dkk1	dkk1	PROPN
bjp-61292	116	34	was	be	AUX
bjp-61292	116	35	delivered	deliver	VERB
bjp-61292	116	36	by	by	ADP
bjp-61292	116	37	zoledronic	zoledronic	ADJ
bjp-61292	116	38	acid	acid	NOUN
bjp-61292	116	39	-	-	PUNCT
bjp-61292	116	40	treated	treat	VERB
bjp-61292	116	41	breast	breast	NOUN
bjp-61292	116	42	cancer	cancer	NOUN
bjp-61292	116	43	cells	cell	NOUN
bjp-61292	116	44	derived	derive	VERB
bjp-61292	116	45	exosomes	exosome	NOUN
bjp-61292	116	46	.	.	PUNCT
bjp-61292	117	1	the	the	DET
bjp-61292	117	2	migration	migration	NOUN
bjp-61292	117	3	ability	ability	NOUN
bjp-61292	117	4	was	be	AUX
bjp-61292	117	5	measured	measure	VERB
bjp-61292	117	6	by	by	ADP
bjp-61292	117	7	wound	wound	NOUN
bjp-61292	117	8	healing	healing	NOUN
bjp-61292	117	9	assay	assay	NOUN
bjp-61292	117	10	(	(	PUNCT
bjp-61292	117	11	a	a	NOUN
bjp-61292	117	12	)	)	PUNCT
bjp-61292	117	13	and	and	CCONJ
bjp-61292	117	14	transwell	transwell	NOUN
bjp-61292	117	15	assay	assay	NOUN
bjp-61292	117	16	(	(	PUNCT
bjp-61292	117	17	b	b	NOUN
bjp-61292	117	18	)	)	PUNCT
bjp-61292	117	19	.	.	PUNCT
bjp-61292	118	1	the	the	DET
bjp-61292	118	2	expression	expression	NOUN
bjp-61292	118	3	level	level	NOUN
bjp-61292	118	4	of	of	ADP
bjp-61292	118	5	dkk1	dkk1	PROPN
bjp-61292	118	6	in	in	ADP
bjp-61292	118	7	mda	mda	PROPN
bjp-61292	118	8	-	-	PUNCT
bjp-61292	118	9	mb-453	mb-453	PROPN
bjp-61292	118	10	and	and	CCONJ
bjp-61292	118	11	mda	mda	PROPN
bjp-61292	118	12	-	-	PUNCT
bjp-61292	118	13	mb-231	mb-231	PROPN
bjp-61292	118	14	cells	cell	NOUN
bjp-61292	118	15	was	be	AUX
bjp-61292	118	16	determined	determine	VERB
bjp-61292	118	17	by	by	ADP
bjp-61292	118	18	rt	rt	NOUN
bjp-61292	118	19	-	-	PUNCT
bjp-61292	118	20	pcr	pcr	PROPN
bjp-61292	118	21	(	(	PUNCT
bjp-61292	118	22	c	c	NOUN
bjp-61292	118	23	)	)	PUNCT
bjp-61292	118	24	.	.	PUNCT
bjp-61292	119	1	the	the	DET
bjp-61292	119	2	gene	gene	NOUN
bjp-61292	119	3	expression	expression	NOUN
bjp-61292	119	4	level	level	NOUN
bjp-61292	119	5	of	of	ADP
bjp-61292	119	6	dkk1	dkk1	PROPN
bjp-61292	119	7	in	in	ADP
bjp-61292	119	8	mda	mda	PROPN
bjp-61292	119	9	-	-	PUNCT
bjp-61292	119	10	mb-453	mb-453	NOUN
bjp-61292	119	11	cells	cell	NOUN
bjp-61292	119	12	after	after	ADP
bjp-61292	119	13	treatment	treatment	NOUN
bjp-61292	119	14	of	of	ADP
bjp-61292	119	15	different	different	ADJ
bjp-61292	119	16	concentration	concentration	NOUN
bjp-61292	119	17	of	of	ADP
bjp-61292	119	18	zoledronic	zoledronic	ADJ
bjp-61292	119	19	acid	acid	NOUN
bjp-61292	119	20	was	be	AUX
bjp-61292	119	21	evaluated	evaluate	VERB
bjp-61292	119	22	by	by	ADP
bjp-61292	119	23	rt	rt	NOUN
bjp-61292	119	24	-	-	PUNCT
bjp-61292	119	25	pcr	pcr	PROPN
bjp-61292	119	26	(	(	PUNCT
bjp-61292	119	27	d	d	NOUN
bjp-61292	119	28	)	)	PUNCT
bjp-61292	119	29	.	.	PUNCT
bjp-61292	120	1	the	the	DET
bjp-61292	120	2	protein	protein	NOUN
bjp-61292	120	3	expression	expression	NOUN
bjp-61292	120	4	level	level	NOUN
bjp-61292	120	5	of	of	ADP
bjp-61292	120	6	dkk1	dkk1	PROPN
bjp-61292	120	7	in	in	ADP
bjp-61292	120	8	mda	mda	PROPN
bjp-61292	120	9	-	-	PUNCT
bjp-61292	120	10	mb-453	mb-453	NOUN
bjp-61292	120	11	cells	cell	NOUN
bjp-61292	120	12	after	after	ADP
bjp-61292	120	13	treatment	treatment	NOUN
bjp-61292	120	14	of	of	ADP
bjp-61292	120	15	different	different	ADJ
bjp-61292	120	16	concentration	concentration	NOUN
bjp-61292	120	17	of	of	ADP
bjp-61292	120	18	za	za	PROPN
bjp-61292	120	19	was	be	AUX
bjp-61292	120	20	evaluated	evaluate	VERB
bjp-61292	120	21	by	by	ADP
bjp-61292	120	22	western	western	ADJ
bjp-61292	120	23	blotting	blotting	NOUN
bjp-61292	120	24	(	(	PUNCT
bjp-61292	120	25	e	e	NOUN
bjp-61292	120	26	)	)	PUNCT
bjp-61292	120	27	.	.	PUNCT
bjp-61292	121	1	the	the	DET
bjp-61292	121	2	morphology	morphology	NOUN
bjp-61292	121	3	of	of	ADP
bjp-61292	121	4	extracted	extract	VERB
bjp-61292	121	5	exosomes	exosome	NOUN
bjp-61292	121	6	was	be	AUX
bjp-61292	121	7	visualized	visualize	VERB
bjp-61292	121	8	by	by	ADP
bjp-61292	121	9	tem	tem	PROPN
bjp-61292	121	10	(	(	PUNCT
bjp-61292	121	11	f	f	NOUN
bjp-61292	121	12	)	)	PUNCT
bjp-61292	121	13	.	.	PUNCT
bjp-61292	122	1	the	the	DET
bjp-61292	122	2	expression	expression	NOUN
bjp-61292	122	3	level	level	NOUN
bjp-61292	122	4	of	of	ADP
bjp-61292	122	5	cd63	cd63	PROPN
bjp-61292	122	6	and	and	CCONJ
bjp-61292	122	7	cd81	cd81	PROPN
bjp-61292	122	8	in	in	ADP
bjp-61292	122	9	extracted	extract	VERB
bjp-61292	122	10	exosomes	exosome	NOUN
bjp-61292	122	11	was	be	AUX
bjp-61292	122	12	determined	determine	VERB
bjp-61292	122	13	by	by	ADP
bjp-61292	122	14	western	western	ADJ
bjp-61292	122	15	blotting	blotting	NOUN
bjp-61292	122	16	(	(	PUNCT
bjp-61292	122	17	g	g	NOUN
bjp-61292	122	18	)	)	PUNCT
bjp-61292	122	19	.	.	PUNCT
bjp-61292	123	1	the	the	DET
bjp-61292	123	2	gene	gene	NOUN
bjp-61292	123	3	expression	expression	NOUN
bjp-61292	123	4	level	level	NOUN
bjp-61292	123	5	of	of	ADP
bjp-61292	123	6	dkk1	dkk1	PROPN
bjp-61292	123	7	in	in	ADP
bjp-61292	123	8	exosomes	exosome	NOUN
bjp-61292	123	9	derived	derive	VERB
bjp-61292	123	10	from	from	ADP
bjp-61292	123	11	zoledronic	zoledronic	ADJ
bjp-61292	123	12	acid	acid	NOUN
bjp-61292	123	13	-	-	PUNCT
bjp-61292	123	14	treated	treat	VERB
bjp-61292	123	15	mda	mda	PROPN
bjp-61292	123	16	-	-	PUNCT
bjp-61292	123	17	mb-453	mb-453	NUM
bjp-61292	123	18	cells	cell	NOUN
bjp-61292	123	19	was	be	AUX
bjp-61292	123	20	evaluated	evaluate	VERB
bjp-61292	123	21	by	by	ADP
bjp-61292	123	22	rt	rt	NOUN
bjp-61292	123	23	-	-	PUNCT
bjp-61292	123	24	pcr	pcr	ADJ
bjp-61292	123	25	(	(	PUNCT
bjp-61292	123	26	h	h	NOUN
bjp-61292	123	27	)	)	PUNCT
bjp-61292	123	28	.	.	PUNCT
bjp-61292	124	1	the	the	DET
bjp-61292	124	2	protein	protein	NOUN
bjp-61292	124	3	expression	expression	NOUN
bjp-61292	124	4	level	level	NOUN
bjp-61292	124	5	of	of	ADP
bjp-61292	124	6	dkk1	dkk1	PROPN
bjp-61292	124	7	in	in	ADP
bjp-61292	124	8	exosomes	exosome	NOUN
bjp-61292	124	9	derived	derive	VERB
bjp-61292	124	10	from	from	ADP
bjp-61292	124	11	zoledronic	zoledronic	ADJ
bjp-61292	124	12	acid	acid	NOUN
bjp-61292	124	13	-	-	PUNCT
bjp-61292	124	14	treated	treat	VERB
bjp-61292	124	15	mda	mda	PROPN
bjp-61292	124	16	-	-	PUNCT
bjp-61292	124	17	mb-453	mb-453	NUM
bjp-61292	124	18	cells	cell	NOUN
bjp-61292	124	19	was	be	AUX
bjp-61292	124	20	evaluated	evaluate	VERB
bjp-61292	124	21	by	by	ADP
bjp-61292	124	22	western	western	ADJ
bjp-61292	124	23	blotting	blotting	NOUN
bjp-61292	124	24	(	(	PUNCT
bjp-61292	124	25	i	i	NOUN
bjp-61292	124	26	)	)	PUNCT
bjp-61292	124	27	.	.	PUNCT
bjp-61292	125	1	the	the	DET
bjp-61292	125	2	efficacy	efficacy	NOUN
bjp-61292	125	3	of	of	ADP
bjp-61292	125	4	overexpression	overexpression	NOUN
bjp-61292	125	5	of	of	ADP
bjp-61292	125	6	dkk1	dkk1	PROPN
bjp-61292	125	7	was	be	AUX
bjp-61292	125	8	evaluated	evaluate	VERB
bjp-61292	125	9	by	by	ADP
bjp-61292	125	10	western	western	ADJ
bjp-61292	125	11	blotting	blot	VERB
bjp-61292	125	12	(	(	PUNCT
bjp-61292	125	13	j	j	PROPN
bjp-61292	125	14	)	)	PUNCT
bjp-61292	125	15	.	.	PUNCT
bjp-61292	126	1	the	the	DET
bjp-61292	126	2	morphology	morphology	NOUN
bjp-61292	126	3	of	of	ADP
bjp-61292	126	4	extracted	extract	VERB
bjp-61292	126	5	exosomes	exosome	NOUN
bjp-61292	126	6	was	be	AUX
bjp-61292	126	7	visualized	visualize	VERB
bjp-61292	126	8	by	by	ADP
bjp-61292	126	9	tem	tem	PROPN
bjp-61292	126	10	(	(	PUNCT
bjp-61292	126	11	k	k	NOUN
bjp-61292	126	12	)	)	PUNCT
bjp-61292	126	13	.	.	PUNCT
bjp-61292	127	1	the	the	DET
bjp-61292	127	2	expression	expression	NOUN
bjp-61292	127	3	level	level	NOUN
bjp-61292	127	4	of	of	ADP
bjp-61292	127	5	cd63	cd63	PROPN
bjp-61292	127	6	and	and	CCONJ
bjp-61292	127	7	cd81	cd81	PROPN
bjp-61292	127	8	in	in	ADP
bjp-61292	127	9	extracted	extract	VERB
bjp-61292	127	10	exosomes	exosome	NOUN
bjp-61292	127	11	was	be	AUX
bjp-61292	127	12	determined	determine	VERB
bjp-61292	127	13	by	by	ADP
bjp-61292	127	14	western	western	ADJ
bjp-61292	127	15	blotting	blot	VERB
bjp-61292	127	16	(	(	PUNCT
bjp-61292	127	17	l	l	NOUN
bjp-61292	127	18	)	)	PUNCT
bjp-61292	127	19	.	.	PUNCT
bjp-61292	128	1	the	the	DET
bjp-61292	128	2	expression	expression	NOUN
bjp-61292	128	3	level	level	NOUN
bjp-61292	128	4	of	of	ADP
bjp-61292	128	5	dkk1	dkk1	PROPN
bjp-61292	128	6	in	in	ADP
bjp-61292	128	7	exosomes	exosome	NOUN
bjp-61292	128	8	derived	derive	VERB
bjp-61292	128	9	from	from	ADP
bjp-61292	128	10	mda	mda	PROPN
bjp-61292	128	11	-	-	PUNCT
bjp-61292	128	12	mb-453	mb-453	NOUN
bjp-61292	128	13	cells	cell	NOUN
bjp-61292	128	14	and	and	CCONJ
bjp-61292	128	15	dkk1	dkk1	PROPN
bjp-61292	128	16	-	-	PUNCT
bjp-61292	128	17	overexpressed	overexpresse	VERB
bjp-61292	128	18	mda	mda	PROPN
bjp-61292	128	19	-	-	PUNCT
bjp-61292	128	20	mb-453	mb-453	NOUN
bjp-61292	128	21	cells	cell	NOUN
bjp-61292	128	22	was	be	AUX
bjp-61292	128	23	determined	determine	VERB
bjp-61292	128	24	by	by	ADP
bjp-61292	128	25	rt	rt	PROPN
bjp-61292	128	26	-	-	PUNCT
bjp-61292	128	27	pcr	pcr	ADJ
bjp-61292	128	28	and	and	CCONJ
bjp-61292	128	29	western	western	ADJ
bjp-61292	128	30	blotting	blot	VERB
bjp-61292	128	31	(	(	PUNCT
bjp-61292	128	32	m	m	NOUN
bjp-61292	128	33	)	)	PUNCT
bjp-61292	128	34	(	(	PUNCT
bjp-61292	128	35	p<0.05	p<0.05	PROPN
bjp-61292	128	36	,	,	PUNCT
bjp-61292	128	37	p<0.01	p<0.01	PROPN
bjp-61292	128	38	)	)	PUNCT
bjp-61292	128	39	a	a	DET
bjp-61292	128	40	b	b	NOUN
bjp-61292	128	41	d	d	X
bjp-61292	128	42	e	e	PROPN
bjp-61292	128	43	c	c	NOUN
bjp-61292	128	44	f	f	PROPN
bjp-61292	129	1	g	g	PROPN
bjp-61292	129	2	h	h	NOUN
bjp-61292	130	1	i	i	PRON
bjp-61292	130	2	j	j	PROPN
bjp-61292	131	1	k	k	PROPN
bjp-61292	131	2	l	l	PROPN
bjp-61292	131	3	m	m	VERB
bjp-61292	131	4	96	96	NUM
bjp-61292	131	5	bangladesh	bangladesh	PROPN
bjp-61292	131	6	j	j	PROPN
bjp-61292	131	7	pharmacol	pharmacol	PROPN
bjp-61292	131	8	2022	2022	NUM
bjp-61292	131	9	;	;	PUNCT
bjp-61292	131	10	17	17	NUM
bjp-61292	131	11	:	:	SYM
bjp-61292	131	12	92	92	NUM
bjp-61292	131	13	-	-	SYM
bjp-61292	131	14	101	101	NUM
bjp-61292	131	15	we	we	PRON
bjp-61292	131	16	further	far	ADV
bjp-61292	131	17	checked	check	VERB
bjp-61292	131	18	the	the	DET
bjp-61292	131	19	effects	effect	NOUN
bjp-61292	131	20	of	of	ADP
bjp-61292	131	21	exosomes	exosome	NOUN
bjp-61292	131	22	on	on	ADP
bjp-61292	131	23	the	the	DET
bjp-61292	131	24	emt	emt	PROPN
bjp-61292	131	25	progression	progression	NOUN
bjp-61292	131	26	and	and	CCONJ
bjp-61292	131	27	tgf	tgf	PROPN
bjp-61292	131	28	-	-	PUNCT
bjp-61292	131	29	β	β	PROPN
bjp-61292	131	30	signal	signal	NOUN
bjp-61292	131	31	pathway	pathway	NOUN
bjp-61292	131	32	to	to	PART
bjp-61292	131	33	explore	explore	VERB
bjp-61292	131	34	the	the	DET
bjp-61292	131	35	potential	potential	ADJ
bjp-61292	131	36	mechanism	mechanism	NOUN
bjp-61292	131	37	(	(	PUNCT
bjp-61292	131	38	figure	figure	NOUN
bjp-61292	131	39	5	5	NUM
bjp-61292	131	40	)	)	PUNCT
bjp-61292	131	41	.	.	PUNCT
bjp-61292	132	1	compared	compare	VERB
bjp-61292	132	2	to	to	ADP
bjp-61292	132	3	the	the	DET
bjp-61292	132	4	pbs	pbs	PROPN
bjp-61292	132	5	group	group	NOUN
bjp-61292	132	6	,	,	PUNCT
bjp-61292	132	7	the	the	DET
bjp-61292	132	8	expression	expression	NOUN
bjp-61292	132	9	level	level	NOUN
bjp-61292	132	10	of	of	ADP
bjp-61292	132	11	e	e	NOUN
bjp-61292	132	12	-	-	NOUN
bjp-61292	132	13	cadherin	cadherin	NOUN
bjp-61292	132	14	and	and	CCONJ
bjp-61292	132	15	β	β	NOUN
bjp-61292	132	16	-	-	NOUN
bjp-61292	132	17	catenin	catenin	NOUN
bjp-61292	132	18	was	be	AUX
bjp-61292	132	19	greatly	greatly	ADV
bjp-61292	132	20	elevated	elevated	ADJ
bjp-61292	132	21	and	and	CCONJ
bjp-61292	132	22	the	the	DET
bjp-61292	132	23	expression	expression	NOUN
bjp-61292	132	24	level	level	NOUN
bjp-61292	132	25	of	of	ADP
bjp-61292	132	26	ncadherin	ncadherin	NOUN
bjp-61292	132	27	and	and	CCONJ
bjp-61292	132	28	vimentin	vimentin	NOUN
bjp-61292	132	29	was	be	AUX
bjp-61292	132	30	dramatically	dramatically	ADV
bjp-61292	132	31	declined	decline	VERB
bjp-61292	132	32	by	by	ADP
bjp-61292	132	33	the	the	DET
bjp-61292	132	34	treatment	treatment	NOUN
bjp-61292	132	35	of	of	ADP
bjp-61292	132	36	exosomes	exosome	NOUN
bjp-61292	132	37	derived	derive	VERB
bjp-61292	132	38	from	from	ADP
bjp-61292	132	39	zoledronic	zoledronic	ADJ
bjp-61292	132	40	acid	acid	NOUN
bjp-61292	132	41	-treated	-treate	VERB
bjp-61292	132	42	mda	mda	PROPN
bjp-61292	132	43	-	-	PUNCT
bjp-61292	132	44	mb-453	mb-453	NOUN
bjp-61292	132	45	cells	cell	NOUN
bjp-61292	132	46	.	.	PUNCT
bjp-61292	133	1	in	in	ADP
bjp-61292	133	2	addition	addition	NOUN
bjp-61292	133	3	,	,	PUNCT
bjp-61292	133	4	compared	compare	VERB
bjp-61292	133	5	to	to	ADP
bjp-61292	133	6	pbs	pbs	PROPN
bjp-61292	133	7	,	,	PUNCT
bjp-61292	133	8	smad2	smad2	PROPN
bjp-61292	133	9	,	,	PUNCT
bjp-61292	133	10	smad3	smad3	NOUN
bjp-61292	133	11	,	,	PUNCT
bjp-61292	133	12	snail	snail	NOUN
bjp-61292	133	13	,	,	PUNCT
bjp-61292	133	14	twist	twist	NOUN
bjp-61292	133	15	,	,	PUNCT
bjp-61292	133	16	zeb1	zeb1	PROPN
bjp-61292	133	17	,	,	PUNCT
bjp-61292	133	18	and	and	CCONJ
bjp-61292	133	19	zeb2	zeb2	PROPN
bjp-61292	133	20	were	be	AUX
bjp-61292	133	21	dramatically	dramatically	ADV
bjp-61292	133	22	down	down	ADV
bjp-61292	133	23	-	-	PUNCT
bjp-61292	133	24	regulated	regulate	VERB
bjp-61292	133	25	by	by	ADP
bjp-61292	133	26	the	the	DET
bjp-61292	133	27	treatment	treatment	NOUN
bjp-61292	133	28	of	of	ADP
bjp-61292	133	29	exosomes	exosome	NOUN
bjp-61292	133	30	derived	derive	VERB
bjp-61292	133	31	from	from	ADP
bjp-61292	133	32	zoledronic	zoledronic	ADJ
bjp-61292	133	33	acid	acid	NOUN
bjp-61292	133	34	-	-	PUNCT
bjp-61292	133	35	treated	treat	VERB
bjp-61292	133	36	mdamb-453	mdamb-453	NOUN
bjp-61292	133	37	cells	cell	NOUN
bjp-61292	133	38	.	.	PUNCT
bjp-61292	134	1	discussion	discussion	NOUN
bjp-61292	134	2	the	the	DET
bjp-61292	134	3	formation	formation	NOUN
bjp-61292	134	4	of	of	ADP
bjp-61292	134	5	osteoclasts	osteoclast	NOUN
bjp-61292	134	6	is	be	AUX
bjp-61292	134	7	precisely	precisely	ADV
bjp-61292	134	8	regulated	regulate	VERB
bjp-61292	134	9	by	by	ADP
bjp-61292	134	10	the	the	DET
bjp-61292	134	11	osteoprotegerin	osteoprotegerin	NOUN
bjp-61292	134	12	ligand	ligand	NOUN
bjp-61292	134	13	(	(	PUNCT
bjp-61292	134	14	opgl)/rankl	opgl)/rankl	ADJ
bjp-61292	134	15	/	/	SYM
bjp-61292	134	16	rank	rank	NOUN
bjp-61292	134	17	system	system	NOUN
bjp-61292	134	18	.	.	PUNCT
bjp-61292	135	1	rankl	rankl	PROPN
bjp-61292	135	2	facilitates	facilitate	VERB
bjp-61292	135	3	the	the	DET
bjp-61292	135	4	differentiation	differentiation	NOUN
bjp-61292	135	5	from	from	ADP
bjp-61292	135	6	precursor	precursor	NOUN
bjp-61292	135	7	osteoclasts	osteoclast	NOUN
bjp-61292	135	8	to	to	PART
bjp-61292	135	9	mature	mature	VERB
bjp-61292	135	10	osteoclasts	osteoclast	NOUN
bjp-61292	135	11	by	by	ADP
bjp-61292	135	12	binding	bind	VERB
bjp-61292	135	13	with	with	ADP
bjp-61292	135	14	rank	rank	NOUN
bjp-61292	135	15	located	locate	VERB
bjp-61292	135	16	on	on	ADP
bjp-61292	135	17	the	the	DET
bjp-61292	135	18	membrane	membrane	NOUN
bjp-61292	135	19	of	of	ADP
bjp-61292	135	20	osteoclasts	osteoclast	NOUN
bjp-61292	135	21	(	(	PUNCT
bjp-61292	135	22	khosla	khosla	PROPN
bjp-61292	135	23	2001	2001	NUM
bjp-61292	135	24	)	)	PUNCT
bjp-61292	135	25	.	.	PUNCT
bjp-61292	136	1	wnt	wnt	PROPN
bjp-61292	136	2	/	/	SYM
bjp-61292	136	3	β	β	NOUN
bjp-61292	136	4	-	-	ADJ
bjp-61292	136	5	catenin	catenin	ADJ
bjp-61292	136	6	axis	axis	NOUN
bjp-61292	136	7	regulates	regulate	VERB
bjp-61292	136	8	the	the	DET
bjp-61292	136	9	differentiation	differentiation	NOUN
bjp-61292	136	10	and	and	CCONJ
bjp-61292	136	11	maturity	maturity	NOUN
bjp-61292	136	12	of	of	ADP
bjp-61292	136	13	osteoclasts	osteoclast	NOUN
bjp-61292	136	14	by	by	ADP
bjp-61292	136	15	mediating	mediate	VERB
bjp-61292	136	16	the	the	DET
bjp-61292	136	17	expression	expression	NOUN
bjp-61292	136	18	level	level	NOUN
bjp-61292	136	19	of	of	ADP
bjp-61292	136	20	rankl	rankl	NOUN
bjp-61292	136	21	on	on	ADP
bjp-61292	136	22	osteoblasts	osteoblast	NOUN
bjp-61292	136	23	(	(	PUNCT
bjp-61292	136	24	glass	glass	NOUN
bjp-61292	136	25	et	et	PROPN
bjp-61292	136	26	al	al	PROPN
bjp-61292	136	27	.	.	PROPN
bjp-61292	136	28	,	,	PUNCT
bjp-61292	136	29	2005	2005	NUM
bjp-61292	136	30	)	)	PUNCT
bjp-61292	136	31	.	.	PUNCT
bjp-61292	137	1	the	the	DET
bjp-61292	137	2	mrna	mrna	PROPN
bjp-61292	137	3	expression	expression	NOUN
bjp-61292	137	4	levels	level	NOUN
bjp-61292	137	5	of	of	ADP
bjp-61292	137	6	rankl	rankl	NOUN
bjp-61292	137	7	on	on	ADP
bjp-61292	137	8	osteoblasts	osteoblast	NOUN
bjp-61292	137	9	were	be	AUX
bjp-61292	137	10	suppressed	suppress	VERB
bjp-61292	137	11	by	by	ADP
bjp-61292	137	12	the	the	DET
bjp-61292	137	13	activation	activation	NOUN
bjp-61292	137	14	of	of	ADP
bjp-61292	137	15	wnt	wnt	PROPN
bjp-61292	137	16	/	/	SYM
bjp-61292	137	17	β	β	NOUN
bjp-61292	137	18	-	-	ADJ
bjp-61292	137	19	catenin	catenin	ADJ
bjp-61292	137	20	pathway	pathway	NOUN
bjp-61292	137	21	,	,	PUNCT
bjp-61292	137	22	which	which	PRON
bjp-61292	137	23	contributed	contribute	VERB
bjp-61292	137	24	to	to	ADP
bjp-61292	137	25	the	the	DET
bjp-61292	137	26	declined	decline	VERB
bjp-61292	137	27	production	production	NOUN
bjp-61292	137	28	of	of	ADP
bjp-61292	137	29	osteoclasts	osteoclast	NOUN
bjp-61292	137	30	and	and	CCONJ
bjp-61292	137	31	the	the	DET
bjp-61292	137	32	increase	increase	NOUN
bjp-61292	137	33	of	of	ADP
bjp-61292	137	34	bone	bone	NOUN
bjp-61292	137	35	mass	mass	NOUN
bjp-61292	137	36	(	(	PUNCT
bjp-61292	137	37	spencer	spencer	PROPN
bjp-61292	137	38	et	et	PROPN
bjp-61292	137	39	al	al	PROPN
bjp-61292	137	40	.	.	PROPN
bjp-61292	137	41	,	,	PUNCT
bjp-61292	137	42	2006	2006	NUM
bjp-61292	137	43	)	)	PUNCT
bjp-61292	137	44	.	.	PUNCT
bjp-61292	138	1	the	the	DET
bjp-61292	138	2	facilitated	facilitate	VERB
bjp-61292	138	3	proliferation	proliferation	NOUN
bjp-61292	138	4	of	of	ADP
bjp-61292	138	5	osteoclasts	osteoclast	NOUN
bjp-61292	138	6	will	will	AUX
bjp-61292	138	7	be	be	AUX
bjp-61292	138	8	facilitated	facilitate	VERB
bjp-61292	138	9	,	,	PUNCT
bjp-61292	138	10	the	the	DET
bjp-61292	138	11	bone	bone	NOUN
bjp-61292	138	12	mass	mass	NOUN
bjp-61292	138	13	will	will	AUX
bjp-61292	138	14	be	be	AUX
bjp-61292	138	15	decreased	decrease	VERB
bjp-61292	138	16	,	,	PUNCT
bjp-61292	138	17	and	and	CCONJ
bjp-61292	138	18	the	the	DET
bjp-61292	138	19	bone	bone	NOUN
bjp-61292	138	20	density	density	NOUN
bjp-61292	138	21	will	will	AUX
bjp-61292	138	22	be	be	AUX
bjp-61292	138	23	declined	decline	VERB
bjp-61292	138	24	by	by	ADP
bjp-61292	138	25	the	the	DET
bjp-61292	138	26	knockdown	knockdown	NOUN
bjp-61292	138	27	of	of	ADP
bjp-61292	138	28	βcatenin	βcatenin	PROPN
bjp-61292	138	29	(	(	PUNCT
bjp-61292	138	30	holmen	holmen	PROPN
bjp-61292	138	31	et	et	PROPN
bjp-61292	138	32	al	al	PROPN
bjp-61292	138	33	.	.	PROPN
bjp-61292	138	34	,	,	PUNCT
bjp-61292	138	35	2005	2005	NUM
bjp-61292	138	36	)	)	PUNCT
bjp-61292	138	37	.	.	PUNCT
bjp-61292	139	1	when	when	SCONJ
bjp-61292	139	2	investigating	investigate	VERB
bjp-61292	139	3	the	the	DET
bjp-61292	139	4	function	function	NOUN
bjp-61292	139	5	of	of	ADP
bjp-61292	139	6	dkk	dkk	PROPN
bjp-61292	139	7	family	family	NOUN
bjp-61292	139	8	in	in	ADP
bjp-61292	139	9	the	the	DET
bjp-61292	139	10	differentiation	differentiation	NOUN
bjp-61292	139	11	progression	progression	NOUN
bjp-61292	139	12	from	from	ADP
bjp-61292	139	13	mesenchymal	mesenchymal	ADJ
bjp-61292	139	14	cells	cell	NOUN
bjp-61292	139	15	to	to	ADP
bjp-61292	139	16	osteoblasts	osteoblast	NOUN
bjp-61292	139	17	,	,	PUNCT
bjp-61292	139	18	the	the	DET
bjp-61292	139	19	expression	expression	NOUN
bjp-61292	139	20	level	level	NOUN
bjp-61292	139	21	of	of	ADP
bjp-61292	139	22	m	m	NOUN
bjp-61292	139	23	-	-	ADJ
bjp-61292	139	24	csf	csf	ADJ
bjp-61292	139	25	and	and	CCONJ
bjp-61292	139	26	rankl	rankl	VERB
bjp-61292	139	27	could	could	AUX
bjp-61292	139	28	be	be	AUX
bjp-61292	139	29	elevated	elevate	VERB
bjp-61292	139	30	by	by	ADP
bjp-61292	139	31	dkk1	dkk1	PROPN
bjp-61292	139	32	,	,	PUNCT
bjp-61292	139	33	which	which	PRON
bjp-61292	139	34	further	far	ADV
bjp-61292	139	35	induced	induce	VERB
bjp-61292	139	36	the	the	DET
bjp-61292	139	37	downregulation	downregulation	NOUN
bjp-61292	139	38	of	of	ADP
bjp-61292	139	39	opg	opg	NOUN
bjp-61292	139	40	and	and	CCONJ
bjp-61292	139	41	the	the	DET
bjp-61292	139	42	production	production	NOUN
bjp-61292	139	43	of	of	ADP
bjp-61292	139	44	osteoclasts	osteoclast	NOUN
bjp-61292	139	45	(	(	PUNCT
bjp-61292	139	46	fujita	fujita	PROPN
bjp-61292	139	47	and	and	CCONJ
bjp-61292	139	48	janz	janz	PROPN
bjp-61292	139	49	,	,	PUNCT
bjp-61292	139	50	2007	2007	NUM
bjp-61292	139	51	)	)	PUNCT
bjp-61292	139	52	.	.	PUNCT
bjp-61292	140	1	therefore	therefore	ADV
bjp-61292	140	2	,	,	PUNCT
bjp-61292	140	3	as	as	ADP
bjp-61292	140	4	an	an	DET
bjp-61292	140	5	important	important	ADJ
bjp-61292	140	6	inhibitor	inhibitor	NOUN
bjp-61292	140	7	of	of	ADP
bjp-61292	140	8	wnt	wnt	PROPN
bjp-61292	140	9	/	/	SYM
bjp-61292	140	10	β	β	NOUN
bjp-61292	140	11	-	-	ADJ
bjp-61292	140	12	catenin	catenin	ADJ
bjp-61292	140	13	pathway	pathway	NOUN
bjp-61292	140	14	,	,	PUNCT
bjp-61292	140	15	dkk1	dkk1	PROPN
bjp-61292	140	16	exerts	exert	VERB
bjp-61292	140	17	important	important	ADJ
bjp-61292	140	18	roles	role	NOUN
bjp-61292	140	19	in	in	ADP
bjp-61292	140	20	facilitating	facilitate	VERB
bjp-61292	140	21	the	the	DET
bjp-61292	140	22	differentiation	differentiation	NOUN
bjp-61292	140	23	and	and	CCONJ
bjp-61292	140	24	maturity	maturity	NOUN
bjp-61292	140	25	of	of	ADP
bjp-61292	140	26	osteoclasts	osteoclast	NOUN
bjp-61292	140	27	.	.	PUNCT
bjp-61292	141	1	we	we	PRON
bjp-61292	141	2	found	find	VERB
bjp-61292	141	3	that	that	SCONJ
bjp-61292	141	4	dkk1	dkk1	PROPN
bjp-61292	141	5	was	be	AUX
bjp-61292	141	6	highly	highly	ADV
bjp-61292	141	7	expressed	express	VERB
bjp-61292	141	8	in	in	ADP
bjp-61292	141	9	breast	breast	NOUN
bjp-61292	141	10	cancer	cancer	NOUN
bjp-61292	141	11	cells	cell	NOUN
bjp-61292	141	12	,	,	PUNCT
bjp-61292	141	13	which	which	PRON
bjp-61292	141	14	was	be	AUX
bjp-61292	141	15	significantly	significantly	ADV
bjp-61292	141	16	down	down	ADV
bjp-61292	141	17	-	-	PUNCT
bjp-61292	141	18	regulated	regulate	VERB
bjp-61292	141	19	by	by	ADP
bjp-61292	141	20	zoledronic	zoledronic	ADJ
bjp-61292	141	21	acid	acid	NOUN
bjp-61292	141	22	,	,	PUNCT
bjp-61292	141	23	an	an	DET
bjp-61292	141	24	inhibitor	inhibitor	NOUN
bjp-61292	141	25	of	of	ADP
bjp-61292	141	26	osteoclasts	osteoclast	NOUN
bjp-61292	141	27	.	.	PUNCT
bjp-61292	142	1	interestingly	interestingly	ADV
bjp-61292	142	2	,	,	PUNCT
bjp-61292	142	3	after	after	ADP
bjp-61292	142	4	the	the	DET
bjp-61292	142	5	treatment	treatment	NOUN
bjp-61292	142	6	of	of	ADP
bjp-61292	142	7	zoledronic	zoledronic	ADJ
bjp-61292	142	8	acid	acid	NOUN
bjp-61292	142	9	,	,	PUNCT
bjp-61292	142	10	dkk1	dkk1	PROPN
bjp-61292	142	11	in	in	ADP
bjp-61292	142	12	exosomes	exosome	NOUN
bjp-61292	142	13	derived	derive	VERB
bjp-61292	142	14	from	from	ADP
bjp-61292	142	15	breast	breast	NOUN
bjp-61292	142	16	cancer	cancer	NOUN
bjp-61292	142	17	cells	cell	NOUN
bjp-61292	142	18	was	be	AUX
bjp-61292	142	19	also	also	ADV
bjp-61292	142	20	down	down	ADV
bjp-61292	142	21	-	-	PUNCT
bjp-61292	142	22	regulated	regulate	VERB
bjp-61292	142	23	,	,	PUNCT
bjp-61292	142	24	indicating	indicate	VERB
bjp-61292	142	25	that	that	SCONJ
bjp-61292	142	26	dkk1	dkk1	PROPN
bjp-61292	142	27	might	might	AUX
bjp-61292	142	28	be	be	AUX
bjp-61292	142	29	delivered	deliver	VERB
bjp-61292	142	30	by	by	ADP
bjp-61292	142	31	exosomes	exosome	NOUN
bjp-61292	142	32	from	from	ADP
bjp-61292	142	33	breast	breast	NOUN
bjp-61292	142	34	cancer	cancer	NOUN
bjp-61292	142	35	cells	cell	NOUN
bjp-61292	142	36	.	.	PUNCT
bjp-61292	143	1	to	to	PART
bjp-61292	143	2	verify	verify	VERB
bjp-61292	143	3	our	our	PRON
bjp-61292	143	4	hypothesis	hypothesis	NOUN
bjp-61292	143	5	,	,	PUNCT
bjp-61292	143	6	the	the	DET
bjp-61292	143	7	dkk1	dkk1	PROPN
bjp-61292	143	8	overexpressed	overexpresse	VERB
bjp-61292	143	9	breast	breast	NOUN
bjp-61292	143	10	cancer	cancer	NOUN
bjp-61292	143	11	cells	cell	NOUN
bjp-61292	143	12	were	be	AUX
bjp-61292	143	13	established	establish	VERB
bjp-61292	143	14	.	.	PUNCT
bjp-61292	144	1	we	we	PRON
bjp-61292	144	2	found	find	VERB
bjp-61292	144	3	that	that	SCONJ
bjp-61292	144	4	dkk1	dkk1	PROPN
bjp-61292	144	5	was	be	AUX
bjp-61292	144	6	also	also	ADV
bjp-61292	144	7	up	up	ADV
bjp-61292	144	8	-	-	PUNCT
bjp-61292	144	9	regulated	regulate	VERB
bjp-61292	144	10	in	in	ADP
bjp-61292	144	11	exosomes	exosome	NOUN
bjp-61292	144	12	extracted	extract	VERB
bjp-61292	144	13	from	from	ADP
bjp-61292	144	14	dkk1	dkk1	PROPN
bjp-61292	144	15	overexpressed	overexpresse	VERB
bjp-61292	144	16	breast	breast	NOUN
bjp-61292	144	17	cancer	cancer	NOUN
bjp-61292	144	18	cells	cell	NOUN
bjp-61292	144	19	.	.	PUNCT
bjp-61292	145	1	therefore	therefore	ADV
bjp-61292	145	2	,	,	PUNCT
bjp-61292	145	3	we	we	PRON
bjp-61292	145	4	suspected	suspect	VERB
bjp-61292	145	5	that	that	SCONJ
bjp-61292	145	6	exosomes	exosome	NOUN
bjp-61292	145	7	carrying	carry	VERB
bjp-61292	145	8	dkk1	dkk1	PROPN
bjp-61292	145	9	figure	figure	NOUN
bjp-61292	145	10	2	2	NUM
bjp-61292	145	11	:	:	PUNCT
bjp-61292	145	12	exosomes	exosome	NOUN
bjp-61292	145	13	derived	derive	VERB
bjp-61292	145	14	from	from	ADP
bjp-61292	145	15	zoledronic	zoledronic	ADJ
bjp-61292	145	16	acid	acid	NOUN
bjp-61292	145	17	-	-	PUNCT
bjp-61292	145	18	treated	treat	VERB
bjp-61292	145	19	mda	mda	PROPN
bjp-61292	145	20	-	-	PUNCT
bjp-61292	145	21	mb-453	mb-453	NOUN
bjp-61292	145	22	cells	cell	NOUN
bjp-61292	145	23	suppressed	suppress	VERB
bjp-61292	145	24	the	the	DET
bjp-61292	145	25	migration	migration	NOUN
bjp-61292	145	26	of	of	ADP
bjp-61292	145	27	breast	breast	NOUN
bjp-61292	145	28	cancer	cancer	NOUN
bjp-61292	145	29	cells	cell	NOUN
bjp-61292	145	30	.	.	PUNCT
bjp-61292	146	1	cell	cell	NOUN
bjp-61292	146	2	viability	viability	NOUN
bjp-61292	146	3	was	be	AUX
bjp-61292	146	4	detected	detect	VERB
bjp-61292	146	5	by	by	ADP
bjp-61292	146	6	mtt	mtt	PROPN
bjp-61292	146	7	assay	assay	NOUN
bjp-61292	146	8	(	(	PUNCT
bjp-61292	146	9	a	a	NOUN
bjp-61292	146	10	)	)	PUNCT
bjp-61292	146	11	.	.	PUNCT
bjp-61292	147	1	the	the	DET
bjp-61292	147	2	number	number	NOUN
bjp-61292	147	3	of	of	ADP
bjp-61292	147	4	colonies	colony	NOUN
bjp-61292	147	5	was	be	AUX
bjp-61292	147	6	detected	detect	VERB
bjp-61292	147	7	by	by	ADP
bjp-61292	147	8	the	the	DET
bjp-61292	147	9	colon	colon	NOUN
bjp-61292	147	10	formation	formation	NOUN
bjp-61292	147	11	assay	assay	VERB
bjp-61292	147	12	(	(	PUNCT
bjp-61292	147	13	b	b	NOUN
bjp-61292	147	14	)	)	PUNCT
bjp-61292	147	15	.	.	PUNCT
bjp-61292	148	1	the	the	DET
bjp-61292	148	2	number	number	NOUN
bjp-61292	148	3	of	of	ADP
bjp-61292	148	4	migrated	migrate	VERB
bjp-61292	148	5	cells	cell	NOUN
bjp-61292	148	6	was	be	AUX
bjp-61292	148	7	detected	detect	VERB
bjp-61292	148	8	by	by	ADP
bjp-61292	148	9	transwell	transwell	NOUN
bjp-61292	148	10	assay	assay	NOUN
bjp-61292	148	11	(	(	PUNCT
bjp-61292	148	12	c	c	NOUN
bjp-61292	148	13	)	)	PUNCT
bjp-61292	148	14	.	.	PUNCT
bjp-61292	149	1	the	the	DET
bjp-61292	149	2	wound	wound	NOUN
bjp-61292	149	3	width	width	NOUN
bjp-61292	149	4	was	be	AUX
bjp-61292	149	5	detected	detect	VERB
bjp-61292	149	6	by	by	ADP
bjp-61292	149	7	wound	wound	NOUN
bjp-61292	149	8	healing	healing	NOUN
bjp-61292	149	9	assay	assay	NOUN
bjp-61292	149	10	(	(	PUNCT
bjp-61292	149	11	d	d	NOUN
bjp-61292	149	12	)	)	PUNCT
bjp-61292	149	13	(	(	PUNCT
bjp-61292	149	14	p<0.05	p<0.05	NOUN
bjp-61292	149	15	,	,	PUNCT
bjp-61292	149	16	p<0.01	p<0.01	PROPN
bjp-61292	149	17	)	)	PUNCT
bjp-61292	149	18	a	a	DET
bjp-61292	149	19	b	b	NOUN
bjp-61292	149	20	c	c	NOUN
bjp-61292	149	21	d	d	PROPN
bjp-61292	149	22	bangladesh	bangladesh	PROPN
bjp-61292	149	23	j	j	PROPN
bjp-61292	149	24	pharmacol	pharmacol	PROPN
bjp-61292	149	25	2022	2022	NUM
bjp-61292	149	26	;	;	PUNCT
bjp-61292	149	27	17	17	NUM
bjp-61292	149	28	:	:	SYM
bjp-61292	149	29	92	92	NUM
bjp-61292	149	30	-	-	SYM
bjp-61292	149	31	101	101	NUM
bjp-61292	149	32	97	97	NUM
bjp-61292	149	33	might	might	AUX
bjp-61292	149	34	be	be	AUX
bjp-61292	149	35	an	an	DET
bjp-61292	149	36	important	important	ADJ
bjp-61292	149	37	stimulator	stimulator	NOUN
bjp-61292	149	38	for	for	ADP
bjp-61292	149	39	the	the	DET
bjp-61292	149	40	differentiation	differentiation	NOUN
bjp-61292	149	41	and	and	CCONJ
bjp-61292	149	42	maturity	maturity	NOUN
bjp-61292	149	43	of	of	ADP
bjp-61292	149	44	osteoclasts	osteoclast	NOUN
bjp-61292	149	45	,	,	PUNCT
bjp-61292	149	46	which	which	PRON
bjp-61292	149	47	contributed	contribute	VERB
bjp-61292	149	48	to	to	ADP
bjp-61292	149	49	bone	bone	NOUN
bjp-61292	149	50	metastasis	metastasis	NOUN
bjp-61292	149	51	.	.	PUNCT
bjp-61292	150	1	tumor	tumor	NOUN
bjp-61292	150	2	-	-	PUNCT
bjp-61292	150	3	stromal	stromal	ADJ
bjp-61292	150	4	interaction	interaction	NOUN
bjp-61292	150	5	exerts	exert	VERB
bjp-61292	150	6	an	an	DET
bjp-61292	150	7	important	important	ADJ
bjp-61292	150	8	role	role	NOUN
bjp-61292	150	9	in	in	ADP
bjp-61292	150	10	facilitating	facilitate	VERB
bjp-61292	150	11	the	the	DET
bjp-61292	150	12	bone	bone	NOUN
bjp-61292	150	13	metastasis	metastasis	NOUN
bjp-61292	150	14	of	of	ADP
bjp-61292	150	15	breast	breast	NOUN
bjp-61292	150	16	cancer	cancer	NOUN
bjp-61292	150	17	and	and	CCONJ
bjp-61292	150	18	the	the	DET
bjp-61292	150	19	tumor	tumor	NOUN
bjp-61292	150	20	-	-	PUNCT
bjp-61292	150	21	stromal	stromal	ADJ
bjp-61292	150	22	interface	interface	NOUN
bjp-61292	150	23	during	during	ADP
bjp-61292	150	24	bone	bone	NOUN
bjp-61292	150	25	metastasis	metastasis	NOUN
bjp-61292	150	26	is	be	AUX
bjp-61292	150	27	figure	figure	NOUN
bjp-61292	150	28	3	3	NUM
bjp-61292	150	29	:	:	PUNCT
bjp-61292	150	30	exosomes	exosome	NOUN
bjp-61292	150	31	derived	derive	VERB
bjp-61292	150	32	from	from	ADP
bjp-61292	150	33	zoledronic	zoledronic	ADJ
bjp-61292	150	34	acid	acid	NOUN
bjp-61292	150	35	-	-	PUNCT
bjp-61292	150	36	treated	treat	VERB
bjp-61292	150	37	mda	mda	PROPN
bjp-61292	150	38	-	-	PUNCT
bjp-61292	150	39	mb-453	mb-453	NUM
bjp-61292	150	40	cells	cell	NOUN
bjp-61292	150	41	inhibited	inhibit	VERB
bjp-61292	150	42	the	the	DET
bjp-61292	150	43	differentiation	differentiation	NOUN
bjp-61292	150	44	and	and	CCONJ
bjp-61292	150	45	maturity	maturity	NOUN
bjp-61292	150	46	of	of	ADP
bjp-61292	150	47	osteoclasts	osteoclast	NOUN
bjp-61292	150	48	.	.	PUNCT
bjp-61292	151	1	the	the	DET
bjp-61292	151	2	differentiation	differentiation	NOUN
bjp-61292	151	3	of	of	ADP
bjp-61292	151	4	osteoclasts	osteoclast	NOUN
bjp-61292	151	5	was	be	AUX
bjp-61292	151	6	evaluated	evaluate	VERB
bjp-61292	151	7	by	by	ADP
bjp-61292	151	8	trap	trap	NOUN
bjp-61292	151	9	staining	stain	VERB
bjp-61292	151	10	assay	assay	NOUN
bjp-61292	151	11	(	(	PUNCT
bjp-61292	151	12	a	a	NOUN
bjp-61292	151	13	)	)	PUNCT
bjp-61292	151	14	.	.	PUNCT
bjp-61292	152	1	the	the	DET
bjp-61292	152	2	identification	identification	NOUN
bjp-61292	152	3	of	of	ADP
bjp-61292	152	4	osteoclasts	osteoclast	NOUN
bjp-61292	152	5	tracing	trace	VERB
bjp-61292	152	6	the	the	DET
bjp-61292	152	7	location	location	NOUN
bjp-61292	152	8	of	of	ADP
bjp-61292	152	9	exosomes	exosome	NOUN
bjp-61292	152	10	in	in	ADP
bjp-61292	152	11	raw	raw	ADJ
bjp-61292	152	12	264.7	264.7	NUM
bjp-61292	152	13	cells	cell	NOUN
bjp-61292	152	14	were	be	AUX
bjp-61292	152	15	determined	determine	VERB
bjp-61292	152	16	by	by	ADP
bjp-61292	152	17	immunostaining	immunostaine	VERB
bjp-61292	152	18	assay	assay	PROPN
bjp-61292	152	19	on	on	ADP
bjp-61292	152	20	phalloidine	phalloidine	PROPN
bjp-61292	152	21	and	and	CCONJ
bjp-61292	152	22	pkh67	pkh67	PROPN
bjp-61292	152	23	,	,	PUNCT
bjp-61292	152	24	respectively	respectively	ADV
bjp-61292	152	25	(	(	PUNCT
bjp-61292	152	26	b	b	NOUN
bjp-61292	152	27	)	)	PUNCT
bjp-61292	152	28	.	.	PUNCT
bjp-61292	153	1	the	the	DET
bjp-61292	153	2	quantification	quantification	NOUN
bjp-61292	153	3	of	of	ADP
bjp-61292	153	4	trap	trap	NOUN
bjp-61292	153	5	staining	stain	VERB
bjp-61292	153	6	assay	assay	NOUN
bjp-61292	153	7	was	be	AUX
bjp-61292	153	8	recorded	record	VERB
bjp-61292	153	9	(	(	PUNCT
bjp-61292	153	10	c	c	NOUN
bjp-61292	153	11	)	)	PUNCT
bjp-61292	153	12	.	.	PUNCT
bjp-61292	154	1	the	the	DET
bjp-61292	154	2	gene	gene	NOUN
bjp-61292	154	3	expression	expression	NOUN
bjp-61292	154	4	level	level	NOUN
bjp-61292	154	5	of	of	ADP
bjp-61292	154	6	trap	trap	NOUN
bjp-61292	154	7	,	,	PUNCT
bjp-61292	154	8	oscar	oscar	NOUN
bjp-61292	154	9	,	,	PUNCT
bjp-61292	154	10	c	c	NOUN
bjp-61292	154	11	-	-	PUNCT
bjp-61292	154	12	fos	fos	NOUN
bjp-61292	154	13	,	,	PUNCT
bjp-61292	154	14	and	and	CCONJ
bjp-61292	154	15	nfatcl	nfatcl	PROPN
bjp-61292	154	16	was	be	AUX
bjp-61292	154	17	determined	determine	VERB
bjp-61292	154	18	by	by	ADP
bjp-61292	154	19	rt	rt	NOUN
bjp-61292	154	20	-	-	PUNCT
bjp-61292	154	21	pcr	pcr	ADJ
bjp-61292	154	22	(	(	PUNCT
bjp-61292	154	23	d	d	NOUN
bjp-61292	154	24	)	)	PUNCT
bjp-61292	154	25	.	.	PUNCT
bjp-61292	155	1	the	the	DET
bjp-61292	155	2	protein	protein	NOUN
bjp-61292	155	3	expression	expression	NOUN
bjp-61292	155	4	level	level	NOUN
bjp-61292	155	5	of	of	ADP
bjp-61292	155	6	trap	trap	NOUN
bjp-61292	155	7	,	,	PUNCT
bjp-61292	155	8	oscar	oscar	NOUN
bjp-61292	155	9	,	,	PUNCT
bjp-61292	155	10	c	c	NOUN
bjp-61292	155	11	-	-	PUNCT
bjp-61292	155	12	fos	fos	NOUN
bjp-61292	155	13	,	,	PUNCT
bjp-61292	155	14	and	and	CCONJ
bjp-61292	155	15	nfatcl	nfatcl	PROPN
bjp-61292	155	16	was	be	AUX
bjp-61292	155	17	determined	determine	VERB
bjp-61292	155	18	by	by	ADP
bjp-61292	155	19	western	western	ADJ
bjp-61292	155	20	blotting	blotting	NOUN
bjp-61292	155	21	(	(	PUNCT
bjp-61292	155	22	e	e	NOUN
bjp-61292	155	23	)	)	PUNCT
bjp-61292	155	24	.	.	PUNCT
bjp-61292	156	1	the	the	DET
bjp-61292	156	2	concentration	concentration	NOUN
bjp-61292	156	3	of	of	ADP
bjp-61292	156	4	ctx	ctx	NOUN
bjp-61292	156	5	was	be	AUX
bjp-61292	156	6	measured	measure	VERB
bjp-61292	156	7	by	by	ADP
bjp-61292	156	8	the	the	DET
bjp-61292	156	9	elisa	elisa	PROPN
bjp-61292	156	10	assay	assay	VERB
bjp-61292	156	11	(	(	PUNCT
bjp-61292	156	12	f	f	NOUN
bjp-61292	156	13	)	)	PUNCT
bjp-61292	156	14	.	.	PUNCT
bjp-61292	157	1	the	the	DET
bjp-61292	157	2	concentration	concentration	NOUN
bjp-61292	157	3	of	of	ADP
bjp-61292	157	4	ntx	ntx	NOUN
bjp-61292	157	5	was	be	AUX
bjp-61292	157	6	measured	measure	VERB
bjp-61292	157	7	by	by	ADP
bjp-61292	157	8	the	the	DET
bjp-61292	157	9	elisa	elisa	PROPN
bjp-61292	157	10	assay	assay	VERB
bjp-61292	157	11	(	(	PUNCT
bjp-61292	157	12	g	g	NOUN
bjp-61292	157	13	)	)	PUNCT
bjp-61292	157	14	.	.	PUNCT
bjp-61292	158	1	the	the	DET
bjp-61292	158	2	concentration	concentration	NOUN
bjp-61292	158	3	of	of	ADP
bjp-61292	158	4	tgf	tgf	PROPN
bjp-61292	158	5	-	-	PUNCT
bjp-61292	158	6	β	β	PROPN
bjp-61292	158	7	was	be	AUX
bjp-61292	158	8	measured	measure	VERB
bjp-61292	158	9	by	by	ADP
bjp-61292	158	10	the	the	DET
bjp-61292	158	11	elisa	elisa	PROPN
bjp-61292	158	12	assay	assay	PROPN
bjp-61292	158	13	(	(	PUNCT
bjp-61292	158	14	h	h	NOUN
bjp-61292	158	15	)	)	PUNCT
bjp-61292	158	16	(	(	PUNCT
bjp-61292	158	17	p<0.05	p<0.05	NOUN
bjp-61292	158	18	,	,	PUNCT
bjp-61292	158	19	p<0.01	p<0.01	PROPN
bjp-61292	158	20	)	)	PUNCT
bjp-61292	158	21	a	a	DET
bjp-61292	158	22	b	b	NOUN
bjp-61292	158	23	c	c	NOUN
bjp-61292	158	24	d	d	X
bjp-61292	158	25	e	e	X
bjp-61292	158	26	f	f	PROPN
bjp-61292	158	27	g	g	PROPN
bjp-61292	158	28	h	h	PROPN
bjp-61292	158	29	98	98	NUM
bjp-61292	158	30	bangladesh	bangladesh	PROPN
bjp-61292	158	31	j	j	PROPN
bjp-61292	158	32	pharmacol	pharmacol	PROPN
bjp-61292	158	33	2022	2022	NUM
bjp-61292	158	34	;	;	PUNCT
bjp-61292	158	35	17	17	NUM
bjp-61292	158	36	:	:	SYM
bjp-61292	158	37	92	92	NUM
bjp-61292	158	38	-	-	SYM
bjp-61292	158	39	101	101	NUM
bjp-61292	158	40	mainly	mainly	ADV
bjp-61292	158	41	composed	compose	VERB
bjp-61292	158	42	of	of	ADP
bjp-61292	158	43	tumor	tumor	NOUN
bjp-61292	158	44	cells	cell	NOUN
bjp-61292	158	45	and	and	CCONJ
bjp-61292	158	46	osteoclasts	osteoclast	NOUN
bjp-61292	158	47	(	(	PUNCT
bjp-61292	158	48	liotta	liotta	NOUN
bjp-61292	158	49	and	and	CCONJ
bjp-61292	158	50	kohn	kohn	PROPN
bjp-61292	158	51	2001	2001	NUM
bjp-61292	158	52	;	;	PUNCT
bjp-61292	159	1	lynch	lynch	PROPN
bjp-61292	159	2	et	et	PROPN
bjp-61292	159	3	al	al	PROPN
bjp-61292	159	4	.	.	PROPN
bjp-61292	159	5	,	,	PUNCT
bjp-61292	159	6	2005	2005	NUM
bjp-61292	159	7	)	)	PUNCT
bjp-61292	159	8	.	.	PUNCT
bjp-61292	160	1	the	the	DET
bjp-61292	160	2	differentiation	differentiation	NOUN
bjp-61292	160	3	and	and	CCONJ
bjp-61292	160	4	maturity	maturity	NOUN
bjp-61292	160	5	of	of	ADP
bjp-61292	160	6	osteoclasts	osteoclast	NOUN
bjp-61292	160	7	can	can	AUX
bjp-61292	160	8	be	be	AUX
bjp-61292	160	9	stimulated	stimulate	VERB
bjp-61292	160	10	by	by	ADP
bjp-61292	160	11	cytokines	cytokine	NOUN
bjp-61292	160	12	released	release	VERB
bjp-61292	160	13	by	by	ADP
bjp-61292	160	14	tumor	tumor	NOUN
bjp-61292	160	15	cells	cell	NOUN
bjp-61292	160	16	to	to	PART
bjp-61292	160	17	induce	induce	VERB
bjp-61292	160	18	the	the	DET
bjp-61292	160	19	degradation	degradation	NOUN
bjp-61292	160	20	of	of	ADP
bjp-61292	160	21	bone	bone	NOUN
bjp-61292	160	22	stromal	stromal	ADJ
bjp-61292	160	23	and	and	CCONJ
bjp-61292	160	24	the	the	DET
bjp-61292	160	25	production	production	NOUN
bjp-61292	160	26	of	of	ADP
bjp-61292	160	27	growth	growth	NOUN
bjp-61292	160	28	factors	factor	NOUN
bjp-61292	160	29	stored	store	VERB
bjp-61292	160	30	in	in	ADP
bjp-61292	160	31	the	the	DET
bjp-61292	160	32	bone	bone	NOUN
bjp-61292	160	33	stromal	stromal	NOUN
bjp-61292	160	34	,	,	PUNCT
bjp-61292	160	35	which	which	PRON
bjp-61292	160	36	further	far	ADV
bjp-61292	160	37	facilitates	facilitate	VERB
bjp-61292	160	38	the	the	DET
bjp-61292	160	39	growth	growth	NOUN
bjp-61292	160	40	and	and	CCONJ
bjp-61292	160	41	proliferation	proliferation	NOUN
bjp-61292	160	42	of	of	ADP
bjp-61292	160	43	tumor	tumor	NOUN
bjp-61292	160	44	cells	cell	NOUN
bjp-61292	160	45	(	(	PUNCT
bjp-61292	160	46	weilbaecher	weilbaecher	NOUN
bjp-61292	160	47	et	et	PROPN
bjp-61292	160	48	al	al	PROPN
bjp-61292	160	49	.	.	PROPN
bjp-61292	160	50	,	,	PUNCT
bjp-61292	160	51	2011	2011	NUM
bjp-61292	160	52	)	)	PUNCT
bjp-61292	160	53	.	.	PUNCT
bjp-61292	161	1	it	it	PRON
bjp-61292	161	2	is	be	AUX
bjp-61292	161	3	important	important	ADJ
bjp-61292	161	4	to	to	PART
bjp-61292	161	5	investigate	investigate	VERB
bjp-61292	161	6	the	the	DET
bjp-61292	161	7	molecular	molecular	ADJ
bjp-61292	161	8	mechanism	mechanism	NOUN
bjp-61292	161	9	underlying	underlie	VERB
bjp-61292	161	10	the	the	DET
bjp-61292	161	11	tumor	tumor	NOUN
bjp-61292	161	12	-	-	PUNCT
bjp-61292	161	13	stromal	stromal	ADJ
bjp-61292	161	14	interaction	interaction	NOUN
bjp-61292	161	15	for	for	ADP
bjp-61292	161	16	the	the	DET
bjp-61292	161	17	diagnosis	diagnosis	NOUN
bjp-61292	161	18	,	,	PUNCT
bjp-61292	161	19	prevention	prevention	NOUN
bjp-61292	161	20	,	,	PUNCT
bjp-61292	161	21	and	and	CCONJ
bjp-61292	161	22	treatment	treatment	NOUN
bjp-61292	161	23	of	of	ADP
bjp-61292	161	24	bone	bone	NOUN
bjp-61292	161	25	metastasis	metastasis	NOUN
bjp-61292	161	26	of	of	ADP
bjp-61292	161	27	breast	breast	NOUN
bjp-61292	161	28	cancer	cancer	NOUN
bjp-61292	161	29	(	(	PUNCT
bjp-61292	161	30	kang	kang	PROPN
bjp-61292	161	31	,	,	PUNCT
bjp-61292	161	32	2016	2016	NUM
bjp-61292	161	33	)	)	PUNCT
bjp-61292	161	34	.	.	PUNCT
bjp-61292	162	1	we	we	PRON
bjp-61292	162	2	treated	treat	VERB
bjp-61292	162	3	breast	breast	NOUN
bjp-61292	162	4	cancer	cancer	NOUN
bjp-61292	162	5	cells	cell	NOUN
bjp-61292	162	6	with	with	ADP
bjp-61292	162	7	zoledronic	zoledronic	ADJ
bjp-61292	162	8	acid	acid	NOUN
bjp-61292	162	9	and	and	CCONJ
bjp-61292	162	10	found	find	VERB
bjp-61292	162	11	that	that	SCONJ
bjp-61292	162	12	dkk1	dkk1	PROPN
bjp-61292	162	13	was	be	AUX
bjp-61292	162	14	significantly	significantly	ADV
bjp-61292	162	15	down	down	ADV
bjp-61292	162	16	-	-	PUNCT
bjp-61292	162	17	regulated	regulate	VERB
bjp-61292	162	18	in	in	ADP
bjp-61292	162	19	extracted	extract	VERB
bjp-61292	162	20	exosomes	exosome	NOUN
bjp-61292	162	21	,	,	PUNCT
bjp-61292	162	22	which	which	PRON
bjp-61292	162	23	were	be	AUX
bjp-61292	162	24	utilized	utilize	VERB
bjp-61292	162	25	to	to	PART
bjp-61292	162	26	be	be	AUX
bjp-61292	162	27	incubated	incubate	VERB
bjp-61292	162	28	with	with	ADP
bjp-61292	162	29	breast	breast	NOUN
bjp-61292	162	30	cancer	cancer	NOUN
bjp-61292	162	31	cells	cell	NOUN
bjp-61292	162	32	.	.	PUNCT
bjp-61292	163	1	as	as	ADP
bjp-61292	163	2	a	a	DET
bjp-61292	163	3	consequence	consequence	NOUN
bjp-61292	163	4	,	,	PUNCT
bjp-61292	163	5	the	the	DET
bjp-61292	163	6	proliferation	proliferation	NOUN
bjp-61292	163	7	and	and	CCONJ
bjp-61292	163	8	migration	migration	NOUN
bjp-61292	163	9	of	of	ADP
bjp-61292	163	10	treated	treat	VERB
bjp-61292	163	11	breast	breast	NOUN
bjp-61292	163	12	cancer	cancer	NOUN
bjp-61292	163	13	cells	cell	NOUN
bjp-61292	163	14	were	be	AUX
bjp-61292	163	15	greatly	greatly	ADV
bjp-61292	163	16	suppressed	suppress	VERB
bjp-61292	163	17	.	.	PUNCT
bjp-61292	164	1	in	in	ADP
bjp-61292	164	2	addition	addition	NOUN
bjp-61292	164	3	,	,	PUNCT
bjp-61292	164	4	after	after	ADP
bjp-61292	164	5	incubating	incubate	VERB
bjp-61292	164	6	exosomes	exosome	NOUN
bjp-61292	164	7	with	with	ADP
bjp-61292	164	8	raw264.7	raw264.7	PROPN
bjp-61292	164	9	cells	cell	NOUN
bjp-61292	164	10	,	,	PUNCT
bjp-61292	164	11	the	the	DET
bjp-61292	164	12	differentiation	differentiation	NOUN
bjp-61292	164	13	and	and	CCONJ
bjp-61292	164	14	maturity	maturity	NOUN
bjp-61292	164	15	of	of	ADP
bjp-61292	164	16	osteoclasts	osteoclast	NOUN
bjp-61292	164	17	were	be	AUX
bjp-61292	164	18	dramatically	dramatically	ADV
bjp-61292	164	19	inhibited	inhibit	VERB
bjp-61292	164	20	.	.	PUNCT
bjp-61292	165	1	to	to	PART
bjp-61292	165	2	further	far	ADV
bjp-61292	165	3	verifigure	verifigure	VERB
bjp-61292	165	4	5	5	NUM
bjp-61292	165	5	:	:	PUNCT
bjp-61292	165	6	exosomes	exosome	NOUN
bjp-61292	165	7	derived	derive	VERB
bjp-61292	165	8	from	from	ADP
bjp-61292	165	9	zoledronic	zoledronic	ADJ
bjp-61292	165	10	acid	acid	NOUN
bjp-61292	165	11	-	-	PUNCT
bjp-61292	165	12	treated	treat	VERB
bjp-61292	165	13	mda	mda	PROPN
bjp-61292	165	14	-	-	PUNCT
bjp-61292	165	15	mb-453	mb-453	NOUN
bjp-61292	165	16	cells	cell	NOUN
bjp-61292	165	17	suppressed	suppress	VERB
bjp-61292	165	18	the	the	DET
bjp-61292	165	19	emt	emt	PROPN
bjp-61292	165	20	progression	progression	NOUN
bjp-61292	165	21	and	and	CCONJ
bjp-61292	165	22	tgf	tgf	PROPN
bjp-61292	165	23	-	-	PUNCT
bjp-61292	165	24	β	β	PROPN
bjp-61292	165	25	signal	signal	NOUN
bjp-61292	165	26	pathway	pathway	NOUN
bjp-61292	165	27	.	.	PUNCT
bjp-61292	166	1	the	the	DET
bjp-61292	166	2	expression	expression	NOUN
bjp-61292	166	3	level	level	NOUN
bjp-61292	166	4	of	of	ADP
bjp-61292	166	5	e	e	NOUN
bjp-61292	166	6	-	-	NOUN
bjp-61292	166	7	cadherin	cadherin	NOUN
bjp-61292	166	8	,	,	PUNCT
bjp-61292	166	9	β	β	NOUN
bjp-61292	166	10	-	-	ADJ
bjp-61292	166	11	catenin	catenin	ADJ
bjp-61292	166	12	,	,	PUNCT
bjp-61292	166	13	n	n	CCONJ
bjp-61292	166	14	-	-	PUNCT
bjp-61292	166	15	cadherin	cadherin	NOUN
bjp-61292	166	16	,	,	PUNCT
bjp-61292	166	17	and	and	CCONJ
bjp-61292	166	18	vimentin	vimentin	NOUN
bjp-61292	166	19	was	be	AUX
bjp-61292	166	20	determined	determine	VERB
bjp-61292	166	21	by	by	ADP
bjp-61292	166	22	western	western	ADJ
bjp-61292	166	23	blotting	blotting	NOUN
bjp-61292	166	24	(	(	PUNCT
bjp-61292	166	25	a	a	NOUN
bjp-61292	166	26	)	)	PUNCT
bjp-61292	166	27	.	.	PUNCT
bjp-61292	167	1	the	the	DET
bjp-61292	167	2	expression	expression	NOUN
bjp-61292	167	3	level	level	NOUN
bjp-61292	167	4	of	of	ADP
bjp-61292	167	5	smad2	smad2	PROPN
bjp-61292	167	6	,	,	PUNCT
bjp-61292	167	7	smad3	smad3	NOUN
bjp-61292	167	8	,	,	PUNCT
bjp-61292	167	9	snail	snail	NOUN
bjp-61292	167	10	,	,	PUNCT
bjp-61292	167	11	twist	twist	NOUN
bjp-61292	167	12	,	,	PUNCT
bjp-61292	167	13	zeb1	zeb1	PROPN
bjp-61292	167	14	,	,	PUNCT
bjp-61292	167	15	and	and	CCONJ
bjp-61292	167	16	zeb2	zeb2	PROPN
bjp-61292	167	17	was	be	AUX
bjp-61292	167	18	determined	determine	VERB
bjp-61292	167	19	by	by	ADP
bjp-61292	167	20	western	western	ADJ
bjp-61292	167	21	blotting	blot	VERB
bjp-61292	167	22	(	(	PUNCT
bjp-61292	167	23	b	b	NOUN
bjp-61292	167	24	)	)	PUNCT
bjp-61292	167	25	figure	figure	NOUN
bjp-61292	167	26	4	4	NUM
bjp-61292	167	27	:	:	PUNCT
bjp-61292	167	28	the	the	DET
bjp-61292	167	29	effects	effect	NOUN
bjp-61292	167	30	of	of	ADP
bjp-61292	167	31	exosomes	exosome	NOUN
bjp-61292	167	32	treated	treat	VERB
bjp-61292	167	33	raw	raw	ADJ
bjp-61292	167	34	264.7	264.7	NUM
bjp-61292	167	35	cells	cell	NOUN
bjp-61292	167	36	on	on	ADP
bjp-61292	167	37	the	the	DET
bjp-61292	167	38	proliferation	proliferation	NOUN
bjp-61292	167	39	and	and	CCONJ
bjp-61292	167	40	migration	migration	NOUN
bjp-61292	167	41	of	of	ADP
bjp-61292	167	42	breast	breast	NOUN
bjp-61292	167	43	cancer	cancer	NOUN
bjp-61292	167	44	cells	cell	NOUN
bjp-61292	167	45	.	.	PUNCT
bjp-61292	168	1	cell	cell	NOUN
bjp-61292	168	2	viability	viability	NOUN
bjp-61292	168	3	was	be	AUX
bjp-61292	168	4	detected	detect	VERB
bjp-61292	168	5	by	by	ADP
bjp-61292	168	6	mtt	mtt	PROPN
bjp-61292	168	7	assay	assay	NOUN
bjp-61292	168	8	(	(	PUNCT
bjp-61292	168	9	a	a	NOUN
bjp-61292	168	10	)	)	PUNCT
bjp-61292	168	11	.	.	PUNCT
bjp-61292	169	1	the	the	DET
bjp-61292	169	2	number	number	NOUN
bjp-61292	169	3	of	of	ADP
bjp-61292	169	4	colonies	colony	NOUN
bjp-61292	169	5	was	be	AUX
bjp-61292	169	6	detected	detect	VERB
bjp-61292	169	7	by	by	ADP
bjp-61292	169	8	the	the	DET
bjp-61292	169	9	colon	colon	NOUN
bjp-61292	169	10	formation	formation	NOUN
bjp-61292	169	11	assay	assay	VERB
bjp-61292	169	12	(	(	PUNCT
bjp-61292	169	13	b	b	NOUN
bjp-61292	169	14	)	)	PUNCT
bjp-61292	169	15	.	.	PUNCT
bjp-61292	170	1	the	the	DET
bjp-61292	170	2	number	number	NOUN
bjp-61292	170	3	of	of	ADP
bjp-61292	170	4	migrated	migrate	VERB
bjp-61292	170	5	cells	cell	NOUN
bjp-61292	170	6	was	be	AUX
bjp-61292	170	7	detected	detect	VERB
bjp-61292	170	8	by	by	ADP
bjp-61292	170	9	transwell	transwell	NOUN
bjp-61292	170	10	assay	assay	NOUN
bjp-61292	170	11	(	(	PUNCT
bjp-61292	170	12	c	c	NOUN
bjp-61292	170	13	)	)	PUNCT
bjp-61292	170	14	.	.	PUNCT
bjp-61292	171	1	the	the	DET
bjp-61292	171	2	wound	wound	NOUN
bjp-61292	171	3	width	width	NOUN
bjp-61292	171	4	was	be	AUX
bjp-61292	171	5	detected	detect	VERB
bjp-61292	171	6	by	by	ADP
bjp-61292	171	7	wound	wound	NOUN
bjp-61292	171	8	healing	healing	NOUN
bjp-61292	171	9	assay	assay	NOUN
bjp-61292	171	10	(	(	PUNCT
bjp-61292	171	11	d	d	NOUN
bjp-61292	171	12	)	)	PUNCT
bjp-61292	172	1	[	[	X
bjp-61292	172	2	p<0.05	p<0.05	NOUN
bjp-61292	172	3	,	,	PUNCT
bjp-61292	172	4	p<0.01	p<0.01	PROPN
bjp-61292	172	5	]	]	PUNCT
bjp-61292	172	6	a	a	DET
bjp-61292	172	7	b	b	NOUN
bjp-61292	172	8	a	a	DET
bjp-61292	172	9	b	b	NOUN
bjp-61292	172	10	c	c	NOUN
bjp-61292	172	11	d	d	PROPN
bjp-61292	172	12	bangladesh	bangladesh	PROPN
bjp-61292	172	13	j	j	PROPN
bjp-61292	172	14	pharmacol	pharmacol	PROPN
bjp-61292	172	15	2022	2022	NUM
bjp-61292	172	16	;	;	PUNCT
bjp-61292	172	17	17	17	NUM
bjp-61292	172	18	:	:	SYM
bjp-61292	172	19	92	92	NUM
bjp-61292	172	20	-	-	SYM
bjp-61292	172	21	101	101	NUM
bjp-61292	172	22	99	99	NUM
bjp-61292	172	23	fy	fy	NOUN
bjp-61292	172	24	the	the	DET
bjp-61292	172	25	effects	effect	NOUN
bjp-61292	172	26	of	of	ADP
bjp-61292	172	27	exosomes	exosome	NOUN
bjp-61292	172	28	derived	derive	VERB
bjp-61292	172	29	from	from	ADP
bjp-61292	172	30	cancer	cancer	NOUN
bjp-61292	172	31	cells	cell	NOUN
bjp-61292	172	32	on	on	ADP
bjp-61292	172	33	the	the	DET
bjp-61292	172	34	interaction	interaction	NOUN
bjp-61292	172	35	between	between	ADP
bjp-61292	172	36	breast	breast	NOUN
bjp-61292	172	37	cancer	cancer	NOUN
bjp-61292	172	38	cells	cell	NOUN
bjp-61292	172	39	and	and	CCONJ
bjp-61292	172	40	osteoclasts	osteoclast	NOUN
bjp-61292	172	41	,	,	PUNCT
bjp-61292	172	42	exosomes	exosome	NOUN
bjp-61292	172	43	were	be	AUX
bjp-61292	172	44	added	add	VERB
bjp-61292	172	45	into	into	ADP
bjp-61292	172	46	the	the	DET
bjp-61292	172	47	co	co	ADJ
bjp-61292	172	48	-	-	ADJ
bjp-61292	172	49	cultural	cultural	ADJ
bjp-61292	172	50	system	system	NOUN
bjp-61292	172	51	of	of	ADP
bjp-61292	172	52	raw264.7	raw264.7	PROPN
bjp-61292	172	53	cells	cell	NOUN
bjp-61292	172	54	and	and	CCONJ
bjp-61292	172	55	breast	breast	NOUN
bjp-61292	172	56	cancer	cancer	NOUN
bjp-61292	172	57	cells	cell	NOUN
bjp-61292	172	58	.	.	PUNCT
bjp-61292	173	1	we	we	PRON
bjp-61292	173	2	found	find	VERB
bjp-61292	173	3	that	that	SCONJ
bjp-61292	173	4	the	the	DET
bjp-61292	173	5	proliferation	proliferation	NOUN
bjp-61292	173	6	and	and	CCONJ
bjp-61292	173	7	migration	migration	NOUN
bjp-61292	173	8	of	of	ADP
bjp-61292	173	9	breast	breast	NOUN
bjp-61292	173	10	cancer	cancer	NOUN
bjp-61292	173	11	cells	cell	NOUN
bjp-61292	173	12	were	be	AUX
bjp-61292	173	13	dramatically	dramatically	ADV
bjp-61292	173	14	facilitated	facilitate	VERB
bjp-61292	173	15	.	.	PUNCT
bjp-61292	174	1	these	these	DET
bjp-61292	174	2	data	datum	NOUN
bjp-61292	174	3	revealed	reveal	VERB
bjp-61292	174	4	that	that	SCONJ
bjp-61292	174	5	the	the	DET
bjp-61292	174	6	differentiation	differentiation	NOUN
bjp-61292	174	7	and	and	CCONJ
bjp-61292	174	8	maturity	maturity	NOUN
bjp-61292	174	9	of	of	ADP
bjp-61292	174	10	osteoclasts	osteoclast	NOUN
bjp-61292	174	11	could	could	AUX
bjp-61292	174	12	be	be	AUX
bjp-61292	174	13	suppressed	suppress	VERB
bjp-61292	174	14	by	by	ADP
bjp-61292	174	15	exosomes	exosome	NOUN
bjp-61292	174	16	derived	derive	VERB
bjp-61292	174	17	from	from	ADP
bjp-61292	174	18	zoledronic	zoledronic	ADJ
bjp-61292	174	19	acid	acid	NOUN
bjp-61292	174	20	-	-	PUNCT
bjp-61292	174	21	treated	treat	VERB
bjp-61292	174	22	breast	breast	NOUN
bjp-61292	174	23	cancer	cancer	NOUN
bjp-61292	174	24	cells	cell	NOUN
bjp-61292	174	25	and	and	CCONJ
bjp-61292	174	26	subsequently	subsequently	ADV
bjp-61292	174	27	prevented	prevent	VERB
bjp-61292	174	28	the	the	DET
bjp-61292	174	29	matured	mature	VERB
bjp-61292	174	30	osteoclasts	osteoclast	NOUN
bjp-61292	174	31	from	from	ADP
bjp-61292	174	32	facilitating	facilitate	VERB
bjp-61292	174	33	the	the	DET
bjp-61292	174	34	proliferation	proliferation	NOUN
bjp-61292	174	35	and	and	CCONJ
bjp-61292	174	36	migration	migration	NOUN
bjp-61292	174	37	of	of	ADP
bjp-61292	174	38	breast	breast	NOUN
bjp-61292	174	39	cancer	cancer	NOUN
bjp-61292	174	40	cells	cell	NOUN
bjp-61292	174	41	.	.	PUNCT
bjp-61292	175	1	emt	emt	PROPN
bjp-61292	175	2	progression	progression	NOUN
bjp-61292	175	3	is	be	AUX
bjp-61292	175	4	an	an	DET
bjp-61292	175	5	important	important	ADJ
bjp-61292	175	6	marker	marker	NOUN
bjp-61292	175	7	for	for	ADP
bjp-61292	175	8	the	the	DET
bjp-61292	175	9	migration	migration	NOUN
bjp-61292	175	10	of	of	ADP
bjp-61292	175	11	cancer	cancer	NOUN
bjp-61292	175	12	cells	cell	NOUN
bjp-61292	175	13	,	,	PUNCT
bjp-61292	175	14	especially	especially	ADV
bjp-61292	175	15	in	in	ADP
bjp-61292	175	16	bone	bone	NOUN
bjp-61292	175	17	metastasis	metastasis	NOUN
bjp-61292	175	18	(	(	PUNCT
bjp-61292	175	19	ren	ren	NOUN
bjp-61292	175	20	et	et	PROPN
bjp-61292	175	21	al	al	PROPN
bjp-61292	175	22	.	.	PROPN
bjp-61292	175	23	,	,	PUNCT
bjp-61292	175	24	2017	2017	NUM
bjp-61292	175	25	)	)	PUNCT
bjp-61292	175	26	.	.	PUNCT
bjp-61292	176	1	in	in	ADP
bjp-61292	176	2	addition	addition	NOUN
bjp-61292	176	3	,	,	PUNCT
bjp-61292	176	4	the	the	DET
bjp-61292	176	5	production	production	NOUN
bjp-61292	176	6	of	of	ADP
bjp-61292	176	7	tgf	tgf	PROPN
bjp-61292	176	8	-	-	PUNCT
bjp-61292	176	9	β	β	PROPN
bjp-61292	176	10	stored	store	VERB
bjp-61292	176	11	in	in	ADP
bjp-61292	176	12	bone	bone	NOUN
bjp-61292	176	13	stromal	stromal	NOUN
bjp-61292	176	14	will	will	AUX
bjp-61292	176	15	be	be	AUX
bjp-61292	176	16	significantly	significantly	ADV
bjp-61292	176	17	induced	induce	VERB
bjp-61292	176	18	by	by	ADP
bjp-61292	176	19	the	the	DET
bjp-61292	176	20	stimulation	stimulation	NOUN
bjp-61292	176	21	of	of	ADP
bjp-61292	176	22	cytokines	cytokine	NOUN
bjp-61292	176	23	released	release	VERB
bjp-61292	176	24	by	by	ADP
bjp-61292	176	25	breast	breast	NOUN
bjp-61292	176	26	cancer	cancer	NOUN
bjp-61292	176	27	cells	cell	NOUN
bjp-61292	176	28	and	and	CCONJ
bjp-61292	176	29	the	the	DET
bjp-61292	176	30	produced	produce	VERB
bjp-61292	176	31	tgf	tgf	PROPN
bjp-61292	176	32	-	-	PUNCT
bjp-61292	176	33	β	β	PROPN
bjp-61292	176	34	further	far	ADV
bjp-61292	176	35	activates	activate	VERB
bjp-61292	176	36	the	the	DET
bjp-61292	176	37	growth	growth	NOUN
bjp-61292	176	38	of	of	ADP
bjp-61292	176	39	tumor	tumor	NOUN
bjp-61292	176	40	cells	cell	NOUN
bjp-61292	176	41	by	by	ADP
bjp-61292	176	42	targeting	target	VERB
bjp-61292	176	43	jagged1	jagged1	NOUN
bjp-61292	176	44	(	(	PUNCT
bjp-61292	176	45	kang	kang	PROPN
bjp-61292	176	46	,	,	PUNCT
bjp-61292	176	47	2016	2016	NUM
bjp-61292	176	48	)	)	PUNCT
bjp-61292	176	49	.	.	PUNCT
bjp-61292	177	1	we	we	PRON
bjp-61292	177	2	found	find	VERB
bjp-61292	177	3	that	that	SCONJ
bjp-61292	177	4	after	after	ADP
bjp-61292	177	5	the	the	DET
bjp-61292	177	6	treatment	treatment	NOUN
bjp-61292	177	7	of	of	ADP
bjp-61292	177	8	exosomes	exosome	NOUN
bjp-61292	177	9	derived	derive	VERB
bjp-61292	177	10	from	from	ADP
bjp-61292	177	11	zoledronic	zoledronic	ADJ
bjp-61292	177	12	acid	acid	NOUN
bjp-61292	177	13	-	-	PUNCT
bjp-61292	177	14	treated	treat	VERB
bjp-61292	177	15	mda	mda	PROPN
bjp-61292	177	16	-	-	PUNCT
bjp-61292	177	17	mb-453	mb-453	NOUN
bjp-61292	177	18	cells	cell	NOUN
bjp-61292	177	19	,	,	PUNCT
bjp-61292	177	20	the	the	DET
bjp-61292	177	21	emt	emt	PROPN
bjp-61292	177	22	progression	progression	NOUN
bjp-61292	177	23	and	and	CCONJ
bjp-61292	177	24	tgf	tgf	PROPN
bjp-61292	177	25	-	-	PUNCT
bjp-61292	177	26	β	β	PROPN
bjp-61292	177	27	pathway	pathway	NOUN
bjp-61292	177	28	were	be	AUX
bjp-61292	177	29	significantly	significantly	ADV
bjp-61292	177	30	suppressed	suppress	VERB
bjp-61292	177	31	,	,	PUNCT
bjp-61292	177	32	indicating	indicate	VERB
bjp-61292	177	33	that	that	SCONJ
bjp-61292	177	34	the	the	DET
bjp-61292	177	35	interaction	interaction	NOUN
bjp-61292	177	36	between	between	ADP
bjp-61292	177	37	tumor	tumor	NOUN
bjp-61292	177	38	cells	cell	NOUN
bjp-61292	177	39	and	and	CCONJ
bjp-61292	177	40	osteoclasts	osteoclast	NOUN
bjp-61292	177	41	might	might	AUX
bjp-61292	177	42	be	be	AUX
bjp-61292	177	43	connected	connect	VERB
bjp-61292	177	44	by	by	ADP
bjp-61292	177	45	exosomes	exosome	NOUN
bjp-61292	177	46	derived	derive	VERB
bjp-61292	177	47	from	from	ADP
bjp-61292	177	48	tumor	tumor	NOUN
bjp-61292	177	49	cells	cell	NOUN
bjp-61292	177	50	,	,	PUNCT
bjp-61292	177	51	which	which	PRON
bjp-61292	177	52	were	be	AUX
bjp-61292	177	53	blocked	block	VERB
bjp-61292	177	54	by	by	ADP
bjp-61292	177	55	the	the	DET
bjp-61292	177	56	treatment	treatment	NOUN
bjp-61292	177	57	of	of	ADP
bjp-61292	177	58	zoledronic	zoledronic	ADJ
bjp-61292	177	59	acid	acid	NOUN
bjp-61292	177	60	.	.	PUNCT
bjp-61292	178	1	conclusion	conclusion	NOUN
bjp-61292	178	2	zoledronic	zoledronic	ADJ
bjp-61292	178	3	acid	acid	PROPN
bjp-61292	178	4	inhibits	inhibit	VERB
bjp-61292	178	5	the	the	DET
bjp-61292	178	6	bone	bone	NOUN
bjp-61292	178	7	metastasis	metastasis	NOUN
bjp-61292	178	8	of	of	ADP
bjp-61292	178	9	breast	breast	NOUN
bjp-61292	178	10	cancer	cancer	NOUN
bjp-61292	178	11	by	by	ADP
bjp-61292	178	12	repressing	repress	VERB
bjp-61292	178	13	exosome	exosome	NOUN
bjp-61292	178	14	-	-	PUNCT
bjp-61292	178	15	loaded	load	VERB
bjp-61292	178	16	dkk1	dkk1	PROPN
bjp-61292	178	17	.	.	PUNCT
bjp-61292	179	1	financial	financial	ADJ
bjp-61292	179	2	support	support	NOUN
bjp-61292	179	3	jiaxing	jiaxing	PROPN
bjp-61292	179	4	key	key	ADJ
bjp-61292	179	5	discipline	discipline	NOUN
bjp-61292	179	6	of	of	ADP
bjp-61292	179	7	medicine	medicine	NOUN
bjp-61292	179	8	-	-	PUNCT
bjp-61292	179	9	oncology	oncology	NOUN
bjp-61292	179	10	(	(	PUNCT
bjp-61292	179	11	supporting	support	VERB
bjp-61292	179	12	subject	subject	NOUN
bjp-61292	179	13	)	)	PUNCT
bjp-61292	179	14	2019	2019	NUM
bjp-61292	179	15	-	-	SYM
bjp-61292	179	16	zc-11	zc-11	NUM
bjp-61292	179	17	and	and	CCONJ
bjp-61292	179	18	science	science	NOUN
bjp-61292	179	19	and	and	CCONJ
bjp-61292	179	20	technology	technology	NOUN
bjp-61292	179	21	project	project	NOUN
bjp-61292	179	22	of	of	ADP
bjp-61292	179	23	jiaxing	jiaxing	PROPN
bjp-61292	179	24	(	(	PUNCT
bjp-61292	179	25	no	no	INTJ
bjp-61292	179	26	.	.	PUNCT
bjp-61292	180	1	2021ay30009	2021ay30009	NUM
bjp-61292	180	2	)	)	PUNCT
bjp-61292	180	3	conflict	conflict	NOUN
bjp-61292	180	4	of	of	ADP
bjp-61292	180	5	interest	interest	NOUN
bjp-61292	180	6	author	author	NOUN
bjp-61292	180	7	declares	declare	VERB
bjp-61292	180	8	no	no	DET
bjp-61292	180	9	conflict	conflict	NOUN
bjp-61292	180	10	of	of	ADP
bjp-61292	180	11	interest	interest	NOUN
bjp-61292	180	12	references	reference	NOUN
bjp-61292	180	13	boyce	boyce	PROPN
bjp-61292	180	14	bf	bf	PROPN
bjp-61292	180	15	.	.	PROPN
bjp-61292	180	16	advances	advance	NOUN
bjp-61292	180	17	in	in	ADP
bjp-61292	180	18	the	the	DET
bjp-61292	180	19	regulation	regulation	NOUN
bjp-61292	180	20	of	of	ADP
bjp-61292	180	21	osteoclasts	osteoclast	NOUN
bjp-61292	180	22	and	and	CCONJ
bjp-61292	180	23	osteoclast	osteoclast	ADJ
bjp-61292	180	24	functions	function	NOUN
bjp-61292	180	25	.	.	PUNCT
bjp-61292	181	1	j	j	PROPN
bjp-61292	181	2	dent	dent	NOUN
bjp-61292	181	3	res	re	NOUN
bjp-61292	181	4	.	.	PUNCT
bjp-61292	181	5	2013	2013	NUM
bjp-61292	181	6	;	;	PUNCT
bjp-61292	181	7	92	92	NUM
bjp-61292	181	8	:	:	PUNCT
bjp-61292	181	9	860	860	NUM
bjp-61292	181	10	-	-	SYM
bjp-61292	181	11	67	67	NUM
bjp-61292	181	12	.	.	PUNCT
bjp-61292	182	1	bryant	bryant	PROPN
bjp-61292	182	2	r	r	PROPN
bjp-61292	182	3	,	,	PUNCT
bjp-61292	182	4	pawlowski	pawlowski	NOUN
bjp-61292	182	5	t	t	PROPN
bjp-61292	182	6	,	,	PUNCT
bjp-61292	182	7	catto	catto	PROPN
bjp-61292	182	8	jw	jw	PROPN
bjp-61292	182	9	,	,	PUNCT
bjp-61292	182	10	marsden	marsden	PROPN
bjp-61292	182	11	g	g	PROPN
bjp-61292	182	12	,	,	PUNCT
bjp-61292	182	13	vessella	vessella	NOUN
bjp-61292	182	14	rl	rl	PROPN
bjp-61292	182	15	,	,	PUNCT
bjp-61292	182	16	rhees	rhees	PROPN
bjp-61292	182	17	b	b	PROPN
bjp-61292	182	18	,	,	PUNCT
bjp-61292	182	19	kuslich	kuslich	PROPN
bjp-61292	182	20	c	c	PROPN
bjp-61292	182	21	,	,	PUNCT
bjp-61292	182	22	visakorpi	visakorpi	PROPN
bjp-61292	182	23	t	t	PROPN
bjp-61292	182	24	,	,	PUNCT
bjp-61292	182	25	hamdy	hamdy	PROPN
bjp-61292	182	26	fc	fc	PROPN
bjp-61292	182	27	.	.	PUNCT
bjp-61292	183	1	changes	change	NOUN
bjp-61292	183	2	in	in	ADP
bjp-61292	183	3	circulating	circulate	VERB
bjp-61292	183	4	microrna	microrna	PROPN
bjp-61292	183	5	levels	level	NOUN
bjp-61292	183	6	associated	associate	VERB
bjp-61292	183	7	with	with	ADP
bjp-61292	183	8	prostate	prostate	NOUN
bjp-61292	183	9	cancer	cancer	NOUN
bjp-61292	183	10	.	.	PUNCT
bjp-61292	184	1	br	br	PROPN
bjp-61292	184	2	j	j	PROPN
bjp-61292	184	3	cancer	cancer	NOUN
bjp-61292	184	4	.	.	PUNCT
bjp-61292	185	1	2012	2012	NUM
bjp-61292	185	2	;	;	PUNCT
bjp-61292	185	3	106	106	NUM
bjp-61292	185	4	:	:	PUNCT
bjp-61292	185	5	768	768	NUM
bjp-61292	185	6	-	-	SYM
bjp-61292	185	7	74	74	NUM
bjp-61292	185	8	.	.	PUNCT
bjp-61292	186	1	chen	chen	PROPN
bjp-61292	186	2	xl	xl	PROPN
bjp-61292	186	3	.	.	PROPN
bjp-61292	186	4	lycorine	lycorine	PROPN
bjp-61292	186	5	inhibits	inhibit	VERB
bjp-61292	186	6	mda	mda	PROPN
bjp-61292	186	7	-	-	PUNCT
bjp-61292	186	8	mb-231	mb-231	PROPN
bjp-61292	186	9	breast	breast	NOUN
bjp-61292	186	10	cancer	cancer	NOUN
bjp-61292	186	11	cells	cell	NOUN
bjp-61292	186	12	proliferation	proliferation	NOUN
bjp-61292	186	13	,	,	PUNCT
bjp-61292	186	14	migration	migration	NOUN
bjp-61292	186	15	and	and	CCONJ
bjp-61292	186	16	invasion	invasion	NOUN
bjp-61292	186	17	is	be	AUX
bjp-61292	186	18	associated	associate	VERB
bjp-61292	186	19	with	with	ADP
bjp-61292	186	20	wnt	wnt	PROPN
bjp-61292	186	21	/	/	SYM
bjp-61292	186	22	β	β	NOUN
bjp-61292	186	23	-	-	ADJ
bjp-61292	186	24	catenin	catenin	ADJ
bjp-61292	186	25	signaling	signaling	NOUN
bjp-61292	186	26	.	.	PUNCT
bjp-61292	187	1	bangladesh	bangladesh	PROPN
bjp-61292	187	2	j	j	PROPN
bjp-61292	187	3	pharmacol	pharmacol	PROPN
bjp-61292	187	4	.	.	PROPN
bjp-61292	188	1	2018	2018	NUM
bjp-61292	188	2	;	;	PUNCT
bjp-61292	188	3	13	13	NUM
bjp-61292	188	4	:	:	SYM
bjp-61292	188	5	192	192	NUM
bjp-61292	188	6	-	-	SYM
bjp-61292	188	7	95	95	NUM
bjp-61292	188	8	.	.	PUNCT
bjp-61292	189	1	chen	chen	PROPN
bjp-61292	189	2	y	y	PROPN
bjp-61292	189	3	,	,	PUNCT
bjp-61292	189	4	whetstone	whetstone	NOUN
bjp-61292	189	5	hc	hc	NOUN
bjp-61292	189	6	,	,	PUNCT
bjp-61292	189	7	youn	youn	PROPN
bjp-61292	189	8	a	a	PRON
bjp-61292	189	9	,	,	PUNCT
bjp-61292	189	10	nadesan	nadesan	ADJ
bjp-61292	189	11	p	p	X
bjp-61292	189	12	,	,	PUNCT
bjp-61292	189	13	chow	chow	PROPN
bjp-61292	189	14	ec	ec	PROPN
bjp-61292	189	15	,	,	PUNCT
bjp-61292	189	16	lin	lin	PROPN
bjp-61292	189	17	ac	ac	PROPN
bjp-61292	189	18	,	,	PUNCT
bjp-61292	189	19	alman	alman	PROPN
bjp-61292	189	20	ba	ba	PROPN
bjp-61292	189	21	.	.	PUNCT
bjp-61292	190	1	beta	beta	NOUN
bjp-61292	190	2	-	-	PUNCT
bjp-61292	190	3	catenin	catenin	NOUN
bjp-61292	190	4	signaling	signal	VERB
bjp-61292	190	5	pathway	pathway	NOUN
bjp-61292	190	6	is	be	AUX
bjp-61292	190	7	crucial	crucial	ADJ
bjp-61292	190	8	for	for	ADP
bjp-61292	190	9	bone	bone	NOUN
bjp-61292	190	10	morphogenetic	morphogenetic	ADJ
bjp-61292	190	11	protein	protein	NOUN
bjp-61292	190	12	2	2	NUM
bjp-61292	190	13	to	to	PART
bjp-61292	190	14	induce	induce	VERB
bjp-61292	190	15	new	new	ADJ
bjp-61292	190	16	bone	bone	NOUN
bjp-61292	190	17	formation	formation	NOUN
bjp-61292	190	18	.	.	PUNCT
bjp-61292	191	1	j	j	PROPN
bjp-61292	191	2	biol	biol	PROPN
bjp-61292	191	3	chem	chem	NOUN
bjp-61292	191	4	.	.	PUNCT
bjp-61292	192	1	2007	2007	NUM
bjp-61292	192	2	;	;	PUNCT
bjp-61292	192	3	282	282	NUM
bjp-61292	192	4	:	:	SYM
bjp-61292	192	5	526	526	NUM
bjp-61292	192	6	-	-	SYM
bjp-61292	192	7	33	33	NUM
bjp-61292	192	8	.	.	PUNCT
bjp-61292	193	1	chicón	chicón	PROPN
bjp-61292	193	2	-	-	PUNCT
bjp-61292	193	3	bosch	bosch	PROPN
bjp-61292	193	4	m	m	PROPN
bjp-61292	193	5	,	,	PUNCT
bjp-61292	193	6	tirado	tirado	VERB
bjp-61292	193	7	om	om	PROPN
bjp-61292	193	8	.	.	PUNCT
bjp-61292	193	9	exosomes	exosome	NOUN
bjp-61292	193	10	in	in	ADP
bjp-61292	193	11	bone	bone	NOUN
bjp-61292	193	12	sarcomas	sarcoma	NOUN
bjp-61292	193	13	:	:	PUNCT
bjp-61292	193	14	key	key	ADJ
bjp-61292	193	15	players	player	NOUN
bjp-61292	193	16	in	in	ADP
bjp-61292	193	17	metastasis	metastasis	NOUN
bjp-61292	193	18	.	.	PUNCT
bjp-61292	194	1	cells	cell	NOUN
bjp-61292	194	2	2020	2020	NUM
bjp-61292	194	3	;	;	PUNCT
bjp-61292	194	4	9	9	NUM
bjp-61292	194	5	:	:	SYM
bjp-61292	194	6	241	241	NUM
bjp-61292	194	7	.	.	PUNCT
bjp-61292	194	8	clezardin	clezardin	VERB
bjp-61292	194	9	p.	p.	NOUN
bjp-61292	194	10	therapeutic	therapeutic	ADJ
bjp-61292	194	11	targets	target	NOUN
bjp-61292	194	12	for	for	ADP
bjp-61292	194	13	bone	bone	NOUN
bjp-61292	194	14	metastases	metastasis	NOUN
bjp-61292	194	15	in	in	ADP
bjp-61292	194	16	breast	breast	NOUN
bjp-61292	194	17	cancer	cancer	NOUN
bjp-61292	194	18	.	.	PUNCT
bjp-61292	195	1	breast	breast	NOUN
bjp-61292	195	2	cancer	cancer	NOUN
bjp-61292	195	3	res	re	NOUN
bjp-61292	195	4	.	.	PUNCT
bjp-61292	196	1	2011	2011	NUM
bjp-61292	196	2	;	;	PUNCT
bjp-61292	196	3	13	13	NUM
bjp-61292	196	4	:	:	SYM
bjp-61292	196	5	207	207	NUM
bjp-61292	196	6	.	.	PUNCT
bjp-61292	197	1	roodman	roodman	PROPN
bjp-61292	197	2	gd	gd	PROPN
bjp-61292	197	3	,	,	PUNCT
bjp-61292	197	4	silbermann	silbermann	PROPN
bjp-61292	197	5	r.	r.	PROPN
bjp-61292	197	6	mechanisms	mechanism	NOUN
bjp-61292	197	7	of	of	ADP
bjp-61292	197	8	osteolytic	osteolytic	ADJ
bjp-61292	197	9	and	and	CCONJ
bjp-61292	197	10	osteoblastic	osteoblastic	ADJ
bjp-61292	197	11	skeletal	skeletal	ADJ
bjp-61292	197	12	lesions	lesion	NOUN
bjp-61292	197	13	.	.	PUNCT
bjp-61292	198	1	bonekey	bonekey	PROPN
bjp-61292	198	2	rep	rep	PROPN
bjp-61292	198	3	.	.	PROPN
bjp-61292	198	4	2015	2015	NUM
bjp-61292	198	5	;	;	PUNCT
bjp-61292	199	1	4	4	NUM
bjp-61292	199	2	:	:	SYM
bjp-61292	199	3	753	753	NUM
bjp-61292	199	4	.	.	PUNCT
bjp-61292	199	5	ell	ell	PROPN
bjp-61292	199	6	b	b	NUM
bjp-61292	199	7	,	,	PUNCT
bjp-61292	199	8	kang	kang	PROPN
bjp-61292	199	9	y.	y.	PROPN
bjp-61292	199	10	snapshot	snapshot	PROPN
bjp-61292	199	11	:	:	PUNCT
bjp-61292	199	12	bone	bone	NOUN
bjp-61292	199	13	metastasis	metastasis	NOUN
bjp-61292	199	14	.	.	PUNCT
bjp-61292	200	1	cell	cell	NOUN
bjp-61292	200	2	2012	2012	NUM
bjp-61292	200	3	;	;	PUNCT
bjp-61292	200	4	151	151	NUM
bjp-61292	200	5	:	:	SYM
bjp-61292	200	6	69090	69090	NUM
bjp-61292	200	7	.	.	PUNCT
bjp-61292	201	1	fujita	fujita	PROPN
bjp-61292	201	2	ki	ki	PROPN
bjp-61292	201	3	,	,	PUNCT
bjp-61292	201	4	janz	janz	PROPN
bjp-61292	201	5	s.	s.	PROPN
bjp-61292	201	6	attenuation	attenuation	PROPN
bjp-61292	201	7	of	of	ADP
bjp-61292	201	8	wnt	wnt	NOUN
bjp-61292	201	9	signaling	signal	VERB
bjp-61292	201	10	by	by	ADP
bjp-61292	201	11	dkk-1	dkk-1	ADV
bjp-61292	201	12	and	and	CCONJ
bjp-61292	201	13	-2	-2	INTJ
bjp-61292	201	14	regulates	regulate	VERB
bjp-61292	201	15	bmp2	bmp2	ADV
bjp-61292	201	16	-	-	PUNCT
bjp-61292	201	17	induced	induce	VERB
bjp-61292	201	18	osteoblast	osteoblast	ADJ
bjp-61292	201	19	differentiation	differentiation	NOUN
bjp-61292	201	20	and	and	CCONJ
bjp-61292	201	21	expression	expression	NOUN
bjp-61292	201	22	of	of	ADP
bjp-61292	201	23	opg	opg	NOUN
bjp-61292	201	24	,	,	PUNCT
bjp-61292	201	25	rankl	rankl	NOUN
bjp-61292	201	26	and	and	CCONJ
bjp-61292	201	27	m	m	PROPN
bjp-61292	201	28	-	-	PUNCT
bjp-61292	201	29	csf	csf	PROPN
bjp-61292	201	30	.	.	PROPN
bjp-61292	201	31	mol	mol	ADP
bjp-61292	201	32	cancer	cancer	NOUN
bjp-61292	201	33	.	.	PUNCT
bjp-61292	202	1	2007	2007	NUM
bjp-61292	202	2	;	;	PUNCT
bjp-61292	202	3	6	6	NUM
bjp-61292	202	4	:	:	SYM
bjp-61292	202	5	71	71	NUM
bjp-61292	202	6	.	.	PUNCT
bjp-61292	202	7	glass	glass	PROPN
bjp-61292	202	8	ii	ii	PROPN
bjp-61292	202	9	da	da	PROPN
bjp-61292	202	10	,	,	PUNCT
bjp-61292	202	11	bialek	bialek	VERB
bjp-61292	202	12	p	p	X
bjp-61292	202	13	,	,	PUNCT
bjp-61292	202	14	ahn	ahn	PROPN
bjp-61292	202	15	jd	jd	PROPN
bjp-61292	202	16	,	,	PUNCT
bjp-61292	202	17	starbuck	starbuck	PROPN
bjp-61292	202	18	m	m	PROPN
bjp-61292	202	19	,	,	PUNCT
bjp-61292	202	20	patel	patel	PROPN
bjp-61292	202	21	ms	ms	PROPN
bjp-61292	202	22	,	,	PUNCT
bjp-61292	202	23	clevers	clever	NOUN
bjp-61292	202	24	h	h	NOUN
bjp-61292	202	25	,	,	PUNCT
bjp-61292	202	26	taketo	taketo	ADJ
bjp-61292	202	27	mm	mm	PROPN
bjp-61292	202	28	,	,	PUNCT
bjp-61292	202	29	long	long	ADJ
bjp-61292	202	30	f	f	PROPN
bjp-61292	202	31	,	,	PUNCT
bjp-61292	202	32	mcmahon	mcmahon	PROPN
bjp-61292	202	33	ap	ap	PROPN
bjp-61292	202	34	,	,	PUNCT
bjp-61292	202	35	lang	lang	PROPN
bjp-61292	202	36	ra	ra	PROPN
bjp-61292	202	37	,	,	PUNCT
bjp-61292	202	38	karsenty	karsenty	PROPN
bjp-61292	202	39	g.	g.	PROPN
bjp-61292	202	40	canonical	canonical	PROPN
bjp-61292	202	41	wnt	wnt	NOUN
bjp-61292	202	42	signaling	signal	VERB
bjp-61292	202	43	in	in	ADP
bjp-61292	202	44	differentiated	differentiated	ADJ
bjp-61292	202	45	osteoblasts	osteoblast	NOUN
bjp-61292	202	46	controls	control	VERB
bjp-61292	202	47	osteoclast	osteoclast	ADJ
bjp-61292	202	48	differentiation	differentiation	NOUN
bjp-61292	202	49	.	.	PUNCT
bjp-61292	203	1	dev	dev	NOUN
bjp-61292	203	2	cell	cell	NOUN
bjp-61292	203	3	.	.	PUNCT
bjp-61292	204	1	2005	2005	NUM
bjp-61292	204	2	;	;	PUNCT
bjp-61292	204	3	8	8	NUM
bjp-61292	204	4	:	:	SYM
bjp-61292	204	5	751	751	NUM
bjp-61292	204	6	-	-	SYM
bjp-61292	204	7	64	64	NUM
bjp-61292	204	8	.	.	PUNCT
bjp-61292	205	1	göbel	göbel	VERB
bjp-61292	205	2	a	a	PRON
bjp-61292	205	3	,	,	PUNCT
bjp-61292	205	4	browne	browne	PROPN
bjp-61292	205	5	aj	aj	PROPN
bjp-61292	205	6	,	,	PUNCT
bjp-61292	205	7	thiele	thiele	PROPN
bjp-61292	205	8	s	s	PROPN
bjp-61292	205	9	,	,	PUNCT
bjp-61292	205	10	rauner	rauner	NOUN
bjp-61292	205	11	m	m	PROPN
bjp-61292	205	12	,	,	PUNCT
bjp-61292	205	13	hofbauer	hofbauer	PROPN
bjp-61292	205	14	lc	lc	PROPN
bjp-61292	205	15	,	,	PUNCT
bjp-61292	205	16	rachner	rachner	NOUN
bjp-61292	205	17	td	td	PROPN
bjp-61292	205	18	.	.	PUNCT
bjp-61292	206	1	potentiated	potentiate	VERB
bjp-61292	206	2	suppression	suppression	NOUN
bjp-61292	206	3	of	of	ADP
bjp-61292	206	4	dickkopf-1	dickkopf-1	PROPN
bjp-61292	206	5	in	in	ADP
bjp-61292	206	6	breast	breast	NOUN
bjp-61292	206	7	cancer	cancer	NOUN
bjp-61292	206	8	by	by	ADP
bjp-61292	206	9	combined	combined	ADJ
bjp-61292	206	10	administration	administration	NOUN
bjp-61292	206	11	of	of	ADP
bjp-61292	206	12	the	the	DET
bjp-61292	206	13	mevalonate	mevalonate	ADJ
bjp-61292	206	14	pathway	pathway	NOUN
bjp-61292	206	15	inhibitors	inhibitor	NOUN
bjp-61292	206	16	zoledronic	zoledronic	ADJ
bjp-61292	206	17	acid	acid	NOUN
bjp-61292	206	18	and	and	CCONJ
bjp-61292	206	19	statins	statin	NOUN
bjp-61292	206	20	.	.	PUNCT
bjp-61292	207	1	breast	breast	NOUN
bjp-61292	207	2	cancer	cancer	NOUN
bjp-61292	207	3	res	re	NOUN
bjp-61292	207	4	treat	treat	NOUN
bjp-61292	207	5	.	.	PUNCT
bjp-61292	208	1	2015	2015	NUM
bjp-61292	208	2	;	;	PUNCT
bjp-61292	208	3	154	154	NUM
bjp-61292	208	4	:	:	SYM
bjp-61292	208	5	623	623	NUM
bjp-61292	208	6	-	-	SYM
bjp-61292	208	7	31	31	NUM
bjp-61292	208	8	.	.	PUNCT
bjp-61292	209	1	goldvaser	goldvaser	PROPN
bjp-61292	209	2	h	h	PROPN
bjp-61292	209	3	,	,	PUNCT
bjp-61292	209	4	amir	amir	PROPN
bjp-61292	209	5	e.	e.	PROPN
bjp-61292	209	6	role	role	PROPN
bjp-61292	209	7	of	of	ADP
bjp-61292	209	8	bisphosphonates	bisphosphonate	NOUN
bjp-61292	209	9	in	in	ADP
bjp-61292	209	10	breast	breast	NOUN
bjp-61292	209	11	cancer	cancer	NOUN
bjp-61292	209	12	therapy	therapy	NOUN
bjp-61292	209	13	.	.	PUNCT
bjp-61292	210	1	curr	curr	PROPN
bjp-61292	210	2	treat	treat	PROPN
bjp-61292	210	3	options	option	NOUN
bjp-61292	210	4	oncol	oncol	ADJ
bjp-61292	210	5	.	.	PUNCT
bjp-61292	211	1	2019	2019	NUM
bjp-61292	211	2	,	,	PUNCT
bjp-61292	211	3	20	20	NUM
bjp-61292	211	4	:	:	SYM
bjp-61292	211	5	1	1	NUM
bjp-61292	211	6	-	-	SYM
bjp-61292	211	7	17	17	NUM
bjp-61292	211	8	.	.	PUNCT
bjp-61292	212	1	guo	guo	PROPN
bjp-61292	212	2	hyb	hyb	PROPN
bjp-61292	212	3	,	,	PUNCT
bjp-61292	212	4	liu	liu	PROPN
bjp-61292	212	5	xx	xx	PROPN
bjp-61292	212	6	,	,	PUNCT
bjp-61292	212	7	zhu	zhu	PROPN
bjp-61292	212	8	xy	xy	PROPN
bjp-61292	212	9	,	,	PUNCT
bjp-61292	212	10	yu	yu	PROPN
bjp-61292	212	11	z.	z.	PROPN
bjp-61292	212	12	mulberrofuran	mulberrofuran	PROPN
bjp-61292	212	13	g	g	PROPN
bjp-61292	212	14	inhibits	inhibit	VERB
bjp-61292	212	15	proliferation	proliferation	NOUN
bjp-61292	212	16	and	and	CCONJ
bjp-61292	212	17	migration	migration	NOUN
bjp-61292	212	18	by	by	ADP
bjp-61292	212	19	inactivating	inactivate	VERB
bjp-61292	212	20	jak2	jak2	PROPN
bjp-61292	212	21	/	/	SYM
bjp-61292	212	22	stat3	stat3	NOUN
bjp-61292	212	23	signaling	signal	VERB
bjp-61292	212	24	in	in	ADP
bjp-61292	212	25	lung	lung	NOUN
bjp-61292	212	26	cancer	cancer	NOUN
bjp-61292	212	27	cells	cell	NOUN
bjp-61292	212	28	.	.	PUNCT
bjp-61292	213	1	bangladesh	bangladesh	PROPN
bjp-61292	213	2	j	j	PROPN
bjp-61292	213	3	pharmacol	pharmacol	PROPN
bjp-61292	213	4	.	.	PROPN
bjp-61292	213	5	2021	2021	NUM
bjp-61292	213	6	;	;	PUNCT
bjp-61292	213	7	16	16	NUM
bjp-61292	213	8	:	:	SYM
bjp-61292	213	9	134	134	NUM
bjp-61292	213	10	-	-	SYM
bjp-61292	213	11	40	40	NUM
bjp-61292	213	12	.	.	PUNCT
bjp-61292	214	1	gürbüz	gürbüz	PROPN
bjp-61292	214	2	p	p	PROPN
bjp-61292	214	3	,	,	PUNCT
bjp-61292	214	4	düzova	düzova	X
bjp-61292	214	5	h	h	PROPN
bjp-61292	214	6	,	,	PUNCT
bjp-61292	214	7	yildiz	yildiz	PROPN
bjp-61292	214	8	a	a	NOUN
bjp-61292	214	9	,	,	PUNCT
bjp-61292	214	10	çakan	çakan	PROPN
bjp-61292	214	11	p	p	X
bjp-61292	214	12	,	,	PUNCT
bjp-61292	214	13	kaya	kaya	PROPN
bjp-61292	214	14	gb	gb	PROPN
bjp-61292	214	15	,	,	PUNCT
bjp-61292	214	16	bağ	bağ	PROPN
bjp-61292	214	17	hgg	hgg	NOUN
bjp-61292	214	18	,	,	PUNCT
bjp-61292	214	19	durhan	durhan	PROPN
bjp-61292	214	20	m	m	PROPN
bjp-61292	214	21	,	,	PUNCT
bjp-61292	214	22	gül	gül	PROPN
bjp-61292	214	23	cc	cc	PROPN
bjp-61292	214	24	,	,	PUNCT
bjp-61292	214	25	taşlidere	taşlidere	PROPN
bjp-61292	214	26	aç	aç	PROPN
bjp-61292	214	27	.	.	PUNCT
bjp-61292	215	1	effects	effect	NOUN
bjp-61292	215	2	of	of	ADP
bjp-61292	215	3	noopept	noopept	NOUN
bjp-61292	215	4	on	on	ADP
bjp-61292	215	5	cognitive	cognitive	ADJ
bjp-61292	215	6	functions	function	NOUN
bjp-61292	215	7	and	and	CCONJ
bjp-61292	215	8	pubertal	pubertal	ADJ
bjp-61292	215	9	process	process	NOUN
bjp-61292	215	10	in	in	ADP
bjp-61292	215	11	rats	rat	NOUN
bjp-61292	215	12	with	with	ADP
bjp-61292	215	13	diabetes	diabetes	NOUN
bjp-61292	215	14	.	.	PUNCT
bjp-61292	216	1	life	life	NOUN
bjp-61292	216	2	sci	sci	PROPN
bjp-61292	216	3	.	.	PROPN
bjp-61292	216	4	2019	2019	NUM
bjp-61292	216	5	;	;	PUNCT
bjp-61292	216	6	233	233	NUM
bjp-61292	216	7	:	:	SYM
bjp-61292	216	8	116698	116698	NUM
bjp-61292	216	9	.	.	PUNCT
bjp-61292	217	1	holmen	holmen	PROPN
bjp-61292	217	2	sl	sl	PROPN
bjp-61292	217	3	,	,	PUNCT
bjp-61292	217	4	zylstra	zylstra	PROPN
bjp-61292	217	5	cr	cr	PROPN
bjp-61292	217	6	,	,	PUNCT
bjp-61292	217	7	mukherjee	mukherjee	PROPN
bjp-61292	217	8	a	a	PROPN
bjp-61292	217	9	,	,	PUNCT
bjp-61292	217	10	sigler	sigler	PROPN
bjp-61292	217	11	re	re	PROPN
bjp-61292	217	12	,	,	PUNCT
bjp-61292	217	13	faugere	faugere	PROPN
bjp-61292	217	14	mc	mc	PROPN
bjp-61292	217	15	,	,	PUNCT
bjp-61292	217	16	bouxsein	bouxsein	PROPN
bjp-61292	217	17	ml	ml	PROPN
bjp-61292	217	18	,	,	PUNCT
bjp-61292	217	19	deng	deng	PROPN
bjp-61292	217	20	l	l	PROPN
bjp-61292	217	21	,	,	PUNCT
bjp-61292	217	22	clemens	clemens	PROPN
bjp-61292	217	23	tl	tl	PROPN
bjp-61292	217	24	,	,	PUNCT
bjp-61292	217	25	williams	williams	PROPN
bjp-61292	217	26	bo	bo	PROPN
bjp-61292	217	27	.	.	PUNCT
bjp-61292	218	1	essential	essential	ADJ
bjp-61292	218	2	role	role	NOUN
bjp-61292	218	3	of	of	ADP
bjp-61292	218	4	beta	beta	NOUN
bjp-61292	218	5	-	-	PUNCT
bjp-61292	218	6	catenin	catenin	NOUN
bjp-61292	218	7	in	in	ADP
bjp-61292	218	8	postnatal	postnatal	ADJ
bjp-61292	218	9	bone	bone	NOUN
bjp-61292	218	10	acquisition	acquisition	NOUN
bjp-61292	218	11	.	.	PUNCT
bjp-61292	219	1	j	j	PROPN
bjp-61292	219	2	biol	biol	PROPN
bjp-61292	219	3	chem	chem	NOUN
bjp-61292	219	4	.	.	PUNCT
bjp-61292	220	1	2005	2005	NUM
bjp-61292	220	2	;	;	PUNCT
bjp-61292	220	3	280	280	NUM
bjp-61292	220	4	:	:	SYM
bjp-61292	220	5	21162	21162	NUM
bjp-61292	220	6	-	-	SYM
bjp-61292	220	7	68	68	NUM
bjp-61292	220	8	.	.	PUNCT
bjp-61292	221	1	huang	huang	PROPN
bjp-61292	221	2	y	y	PROPN
bjp-61292	221	3	,	,	PUNCT
bjp-61292	221	4	liu	liu	PROPN
bjp-61292	221	5	l	l	PROPN
bjp-61292	221	6	,	,	PUNCT
bjp-61292	221	7	liu	liu	PROPN
bjp-61292	221	8	a.	a.	PROPN
bjp-61292	221	9	dickkopf-1	dickkopf-1	PROPN
bjp-61292	221	10	:	:	PUNCT
bjp-61292	221	11	current	current	ADJ
bjp-61292	221	12	knowledge	knowledge	NOUN
bjp-61292	221	13	and	and	CCONJ
bjp-61292	221	14	related	related	ADJ
bjp-61292	221	15	diseases	disease	NOUN
bjp-61292	221	16	.	.	PUNCT
bjp-61292	222	1	life	life	NOUN
bjp-61292	222	2	sci	sci	PROPN
bjp-61292	222	3	.	.	PROPN
bjp-61292	222	4	2018	2018	NUM
bjp-61292	222	5	;	;	PUNCT
bjp-61292	222	6	209	209	NUM
bjp-61292	222	7	:	:	PUNCT
bjp-61292	222	8	249	249	NUM
bjp-61292	222	9	-	-	SYM
bjp-61292	222	10	54	54	NUM
bjp-61292	222	11	.	.	PUNCT
bjp-61292	223	1	kahlert	kahlert	PROPN
bjp-61292	223	2	c	c	PROPN
bjp-61292	223	3	,	,	PUNCT
bjp-61292	223	4	kalluri	kalluri	PROPN
bjp-61292	223	5	r.	r.	PROPN
bjp-61292	223	6	exosomes	exosome	NOUN
bjp-61292	223	7	in	in	ADP
bjp-61292	223	8	tumor	tumor	NOUN
bjp-61292	223	9	microenvironment	microenvironment	ADJ
bjp-61292	223	10	influence	influence	NOUN
bjp-61292	223	11	cancer	cancer	NOUN
bjp-61292	223	12	progression	progression	NOUN
bjp-61292	223	13	and	and	CCONJ
bjp-61292	223	14	metastasis	metastasis	NOUN
bjp-61292	223	15	.	.	PUNCT
bjp-61292	224	1	j	j	PROPN
bjp-61292	224	2	mol	mol	ADP
bjp-61292	224	3	med	med	PROPN
bjp-61292	224	4	(	(	PUNCT
bjp-61292	224	5	berl	berl	PROPN
bjp-61292	224	6	)	)	PUNCT
bjp-61292	224	7	.	.	PUNCT
bjp-61292	225	1	2013	2013	NUM
bjp-61292	225	2	;	;	PUNCT
bjp-61292	225	3	91	91	NUM
bjp-61292	225	4	:	:	SYM
bjp-61292	225	5	431	431	NUM
bjp-61292	225	6	-	-	SYM
bjp-61292	225	7	37	37	NUM
bjp-61292	225	8	.	.	PUNCT
bjp-61292	226	1	kang	kang	PROPN
bjp-61292	226	2	y.	y.	PROPN
bjp-61292	226	3	dissecting	dissect	VERB
bjp-61292	226	4	tumor	tumor	NOUN
bjp-61292	226	5	-	-	PUNCT
bjp-61292	226	6	stromal	stromal	ADJ
bjp-61292	226	7	interactions	interaction	NOUN
bjp-61292	226	8	in	in	ADP
bjp-61292	226	9	breast	breast	NOUN
bjp-61292	226	10	cancer	cancer	NOUN
bjp-61292	226	11	bone	bone	NOUN
bjp-61292	226	12	metastasis	metastasis	NOUN
bjp-61292	226	13	.	.	PUNCT
bjp-61292	227	1	endocrinol	endocrinol	NOUN
bjp-61292	227	2	metab	metab	NOUN
bjp-61292	227	3	(	(	PUNCT
bjp-61292	227	4	seoul	seoul	PROPN
bjp-61292	227	5	)	)	PUNCT
bjp-61292	227	6	.	.	PUNCT
bjp-61292	228	1	2016	2016	NUM
bjp-61292	228	2	;	;	PUNCT
bjp-61292	228	3	31	31	NUM
bjp-61292	228	4	:	:	SYM
bjp-61292	228	5	206	206	NUM
bjp-61292	228	6	-	-	SYM
bjp-61292	228	7	12	12	NUM
bjp-61292	228	8	.	.	PUNCT
bjp-61292	229	1	khosla	khosla	PROPN
bjp-61292	229	2	s.	s.	PROPN
bjp-61292	229	3	minireview	minireview	PROPN
bjp-61292	229	4	:	:	PUNCT
bjp-61292	229	5	the	the	DET
bjp-61292	229	6	opg	opg	PROPN
bjp-61292	229	7	/	/	SYM
bjp-61292	229	8	rankl	rankl	PROPN
bjp-61292	229	9	/	/	SYM
bjp-61292	229	10	rank	rank	NOUN
bjp-61292	229	11	system	system	NOUN
bjp-61292	229	12	.	.	PUNCT
bjp-61292	230	1	endocrinology	endocrinology	NOUN
bjp-61292	230	2	2001	2001	NUM
bjp-61292	230	3	;	;	PUNCT
bjp-61292	230	4	142	142	NUM
bjp-61292	230	5	:	:	PUNCT
bjp-61292	230	6	5050	5050	NUM
bjp-61292	230	7	-	-	SYM
bjp-61292	230	8	55	55	NUM
bjp-61292	230	9	.	.	PUNCT
bjp-61292	231	1	krempien	krempien	PROPN
bjp-61292	231	2	r	r	NOUN
bjp-61292	231	3	,	,	PUNCT
bjp-61292	231	4	niethammer	niethammer	NOUN
bjp-61292	231	5	a	a	NOUN
bjp-61292	231	6	,	,	PUNCT
bjp-61292	231	7	harms	harm	VERB
bjp-61292	231	8	w	w	PROPN
bjp-61292	231	9	,	,	PUNCT
bjp-61292	231	10	debus	debus	PROPN
bjp-61292	231	11	j.	j.	PROPN
bjp-61292	231	12	bisphosphonates	bisphosphonates	PROPN
bjp-61292	231	13	and	and	CCONJ
bjp-61292	231	14	bone	bone	NOUN
bjp-61292	231	15	metastases	metastasis	NOUN
bjp-61292	231	16	:	:	PUNCT
bjp-61292	231	17	current	current	ADJ
bjp-61292	231	18	status	status	NOUN
bjp-61292	231	19	and	and	CCONJ
bjp-61292	231	20	future	future	ADJ
bjp-61292	231	21	directions	direction	NOUN
bjp-61292	231	22	.	.	PUNCT
bjp-61292	232	1	expert	expert	NOUN
bjp-61292	232	2	rev	rev	PROPN
bjp-61292	232	3	anticancer	anticancer	NOUN
bjp-61292	232	4	ther	ther	ADV
bjp-61292	232	5	.	.	PUNCT
bjp-61292	233	1	2005	2005	NUM
bjp-61292	233	2	;	;	PUNCT
bjp-61292	233	3	5	5	NUM
bjp-61292	233	4	:	:	SYM
bjp-61292	233	5	295	295	NUM
bjp-61292	233	6	-	-	SYM
bjp-61292	233	7	305	305	NUM
bjp-61292	233	8	.	.	PUNCT
bjp-61292	234	1	liang	liang	PROPN
bjp-61292	234	2	z	z	PROPN
bjp-61292	234	3	,	,	PUNCT
bjp-61292	234	4	wu	wu	PROPN
bjp-61292	234	5	h	h	PROPN
bjp-61292	234	6	,	,	PUNCT
bjp-61292	234	7	reddy	reddy	PROPN
bjp-61292	234	8	s	s	PROPN
bjp-61292	234	9	,	,	PUNCT
bjp-61292	234	10	zhu	zhu	PROPN
bjp-61292	234	11	a	a	PROPN
bjp-61292	234	12	,	,	PUNCT
bjp-61292	234	13	wang	wang	PROPN
bjp-61292	234	14	s	s	PROPN
bjp-61292	234	15	,	,	PUNCT
bjp-61292	234	16	blevins	blevins	PROPN
bjp-61292	234	17	d	d	PROPN
bjp-61292	234	18	,	,	PUNCT
bjp-61292	234	19	yoon	yoon	PROPN
bjp-61292	234	20	y	y	PROPN
bjp-61292	234	21	,	,	PUNCT
bjp-61292	234	22	zhang	zhang	PROPN
bjp-61292	234	23	y	y	PROPN
bjp-61292	234	24	,	,	PUNCT
bjp-61292	234	25	shim	shim	NOUN
bjp-61292	234	26	h.	h.	PROPN
bjp-61292	234	27	blockade	blockade	NOUN
bjp-61292	234	28	of	of	ADP
bjp-61292	234	29	invasion	invasion	NOUN
bjp-61292	234	30	and	and	CCONJ
bjp-61292	234	31	metastasis	metastasis	NOUN
bjp-61292	234	32	of	of	ADP
bjp-61292	234	33	breast	breast	NOUN
bjp-61292	234	34	cancer	cancer	NOUN
bjp-61292	234	35	cells	cell	NOUN
bjp-61292	234	36	via	via	ADP
bjp-61292	234	37	targeting	target	VERB
bjp-61292	234	38	cxcr4	cxcr4	NOUN
bjp-61292	234	39	with	with	ADP
bjp-61292	234	40	an	an	DET
bjp-61292	234	41	artificial	artificial	ADJ
bjp-61292	234	42	microrna	microrna	PROPN
bjp-61292	234	43	.	.	PUNCT
bjp-61292	235	1	biochem	biochem	PROPN
bjp-61292	235	2	biophys	biophys	PROPN
bjp-61292	235	3	res	re	NOUN
bjp-61292	235	4	commun	commun	PROPN
bjp-61292	235	5	.	.	PUNCT
bjp-61292	236	1	2007	2007	NUM
bjp-61292	236	2	;	;	PUNCT
bjp-61292	236	3	363	363	NUM
bjp-61292	236	4	:	:	SYM
bjp-61292	236	5	542546	542546	NUM
bjp-61292	236	6	.	.	PUNCT
bjp-61292	237	1	100	100	NUM
bjp-61292	237	2	bangladesh	bangladesh	PROPN
bjp-61292	237	3	j	j	PROPN
bjp-61292	237	4	pharmacol	pharmacol	PROPN
bjp-61292	237	5	2022	2022	NUM
bjp-61292	237	6	;	;	PUNCT
bjp-61292	237	7	17	17	NUM
bjp-61292	237	8	:	:	SYM
bjp-61292	237	9	92	92	NUM
bjp-61292	237	10	-	-	SYM
bjp-61292	237	11	101	101	NUM
bjp-61292	237	12	author	author	NOUN
bjp-61292	237	13	info	info	NOUN
bjp-61292	237	14	ming	ming	PROPN
bjp-61292	237	15	chen	chen	PROPN
bjp-61292	237	16	(	(	PUNCT
bjp-61292	237	17	principal	principal	ADJ
bjp-61292	237	18	contact	contact	NOUN
bjp-61292	237	19	)	)	PUNCT
bjp-61292	237	20	e	e	NOUN
bjp-61292	237	21	-	-	NOUN
bjp-61292	237	22	mail	mail	NOUN
bjp-61292	237	23	:	:	PUNCT
bjp-61292	237	24	szchenmingjx@163.com	szchenmingjx@163.com	PROPN
bjp-61292	237	25	liotta	liotta	NOUN
bjp-61292	237	26	la	la	PROPN
bjp-61292	237	27	,	,	PUNCT
bjp-61292	237	28	kohn	kohn	PROPN
bjp-61292	237	29	ec	ec	PROPN
bjp-61292	237	30	.	.	PUNCT
bjp-61292	238	1	the	the	DET
bjp-61292	238	2	microenvironment	microenvironment	NOUN
bjp-61292	238	3	of	of	ADP
bjp-61292	238	4	the	the	DET
bjp-61292	238	5	tumourhost	tumourhost	NOUN
bjp-61292	238	6	interface	interface	NOUN
bjp-61292	238	7	.	.	PUNCT
bjp-61292	239	1	nature	nature	NOUN
bjp-61292	239	2	2001	2001	NUM
bjp-61292	239	3	;	;	PUNCT
bjp-61292	239	4	411	411	NUM
bjp-61292	239	5	:	:	PUNCT
bjp-61292	239	6	375	375	NUM
bjp-61292	239	7	-	-	SYM
bjp-61292	239	8	79	79	NUM
bjp-61292	239	9	.	.	PUNCT
bjp-61292	240	1	liu	liu	PROPN
bjp-61292	240	2	s	s	PROPN
bjp-61292	240	3	,	,	PUNCT
bjp-61292	240	4	wang	wang	PROPN
bjp-61292	240	5	l	l	PROPN
bjp-61292	240	6	,	,	PUNCT
bjp-61292	240	7	zhang	zhang	PROPN
bjp-61292	240	8	r.	r.	PROPN
bjp-61292	240	9	corylin	corylin	PROPN
bjp-61292	240	10	suppresses	suppress	VERB
bjp-61292	240	11	metastasis	metastasis	NOUN
bjp-61292	240	12	of	of	ADP
bjp-61292	240	13	breast	breast	NOUN
bjp-61292	240	14	cancer	cancer	NOUN
bjp-61292	240	15	cells	cell	NOUN
bjp-61292	240	16	by	by	ADP
bjp-61292	240	17	modulating	modulate	VERB
bjp-61292	240	18	mir-34c	mir-34c	NUM
bjp-61292	240	19	/	/	SYM
bjp-61292	240	20	linc00963	linc00963	PROPN
bjp-61292	240	21	target	target	NOUN
bjp-61292	240	22	.	.	PUNCT
bjp-61292	241	1	libyan	libyan	PROPN
bjp-61292	241	2	j	j	PROPN
bjp-61292	241	3	med	med	PROPN
bjp-61292	241	4	.	.	PROPN
bjp-61292	241	5	2021	2021	NUM
bjp-61292	241	6	;	;	PUNCT
bjp-61292	241	7	16	16	NUM
bjp-61292	241	8	:	:	SYM
bjp-61292	241	9	1883224	1883224	NUM
bjp-61292	241	10	.	.	PUNCT
bjp-61292	242	1	lynch	lynch	PROPN
bjp-61292	242	2	cc	cc	PROPN
bjp-61292	242	3	,	,	PUNCT
bjp-61292	242	4	hikosaka	hikosaka	VERB
bjp-61292	242	5	a	a	PRON
bjp-61292	242	6	,	,	PUNCT
bjp-61292	242	7	acuff	acuff	PROPN
bjp-61292	242	8	hb	hb	PROPN
bjp-61292	242	9	,	,	PUNCT
bjp-61292	242	10	martin	martin	PROPN
bjp-61292	242	11	md	md	PROPN
bjp-61292	242	12	,	,	PUNCT
bjp-61292	242	13	kawai	kawai	PROPN
bjp-61292	242	14	n	n	CCONJ
bjp-61292	242	15	,	,	PUNCT
bjp-61292	242	16	singh	singh	PROPN
bjp-61292	242	17	rk	rk	NOUN
bjp-61292	242	18	,	,	PUNCT
bjp-61292	242	19	vargo	vargo	PROPN
bjp-61292	242	20	-	-	PUNCT
bjp-61292	242	21	gogola	gogola	PROPN
bjp-61292	242	22	tc	tc	PROPN
bjp-61292	242	23	,	,	PUNCT
bjp-61292	242	24	begtrup	begtrup	PROPN
bjp-61292	242	25	jl	jl	PROPN
bjp-61292	242	26	,	,	PUNCT
bjp-61292	242	27	peterson	peterson	PROPN
bjp-61292	242	28	te	te	PROPN
bjp-61292	242	29	,	,	PUNCT
bjp-61292	242	30	fingleton	fingleton	PROPN
bjp-61292	242	31	b	b	PROPN
bjp-61292	242	32	,	,	PUNCT
bjp-61292	242	33	shirai	shirai	ADJ
bjp-61292	242	34	t.	t.	NOUN
bjp-61292	242	35	mmp-7	mmp-7	NUM
bjp-61292	242	36	promotes	promote	VERB
bjp-61292	242	37	prostate	prostate	NOUN
bjp-61292	242	38	cancer	cancer	NOUN
bjp-61292	242	39	-	-	PUNCT
bjp-61292	242	40	induced	induce	VERB
bjp-61292	242	41	osteolysis	osteolysis	NOUN
bjp-61292	242	42	via	via	ADP
bjp-61292	242	43	the	the	DET
bjp-61292	242	44	solubilization	solubilization	NOUN
bjp-61292	242	45	of	of	ADP
bjp-61292	242	46	rankl	rankl	NOUN
bjp-61292	242	47	.	.	PUNCT
bjp-61292	243	1	cancer	cancer	NOUN
bjp-61292	243	2	cell	cell	NOUN
bjp-61292	243	3	.	.	PUNCT
bjp-61292	244	1	2005	2005	NUM
bjp-61292	244	2	;	;	PUNCT
bjp-61292	244	3	7	7	NUM
bjp-61292	244	4	:	:	SYM
bjp-61292	244	5	485	485	NUM
bjp-61292	244	6	-	-	SYM
bjp-61292	244	7	96	96	NUM
bjp-61292	244	8	.	.	PUNCT
bjp-61292	245	1	meng	meng	PROPN
bjp-61292	245	2	z	z	PROPN
bjp-61292	245	3	,	,	PUNCT
bjp-61292	245	4	zhang	zhang	PROPN
bjp-61292	245	5	r	r	PROPN
bjp-61292	245	6	,	,	PUNCT
bjp-61292	245	7	wang	wang	PROPN
bjp-61292	245	8	y	y	PROPN
bjp-61292	245	9	,	,	PUNCT
bjp-61292	245	10	zhu	zhu	PROPN
bjp-61292	245	11	g	g	PROPN
bjp-61292	245	12	,	,	PUNCT
bjp-61292	245	13	jin	jin	PROPN
bjp-61292	245	14	t	t	PROPN
bjp-61292	245	15	,	,	PUNCT
bjp-61292	245	16	li	li	PROPN
bjp-61292	245	17	c	c	PROPN
bjp-61292	245	18	,	,	PUNCT
bjp-61292	245	19	zhang	zhang	PROPN
bjp-61292	245	20	s.	s.	PROPN
bjp-61292	245	21	mir200c	mir200c	PROPN
bjp-61292	245	22	/	/	SYM
bjp-61292	245	23	pai-2	pai-2	PRON
bjp-61292	245	24	promotes	promote	VERB
bjp-61292	245	25	the	the	DET
bjp-61292	245	26	progression	progression	NOUN
bjp-61292	245	27	of	of	ADP
bjp-61292	245	28	triple	triple	ADJ
bjp-61292	245	29	negative	negative	ADJ
bjp-61292	245	30	breast	breast	NOUN
bjp-61292	245	31	cancer	cancer	NOUN
bjp-61292	245	32	via	via	ADP
bjp-61292	245	33	m1	m1	PROPN
bjp-61292	245	34	/	/	SYM
bjp-61292	245	35	m2	m2	PROPN
bjp-61292	245	36	polarization	polarization	NOUN
bjp-61292	245	37	induction	induction	NOUN
bjp-61292	245	38	of	of	ADP
bjp-61292	245	39	macrophage	macrophage	NOUN
bjp-61292	245	40	.	.	PUNCT
bjp-61292	246	1	int	int	PROPN
bjp-61292	246	2	immunopharmacol	immunopharmacol	PROPN
bjp-61292	246	3	.	.	PROPN
bjp-61292	247	1	2020	2020	NUM
bjp-61292	247	2	,	,	PUNCT
bjp-61292	247	3	81	81	NUM
bjp-61292	247	4	:	:	SYM
bjp-61292	247	5	106028	106028	NUM
bjp-61292	247	6	.	.	PUNCT
bjp-61292	248	1	miyamoto	miyamoto	NOUN
bjp-61292	248	2	t.	t.	NOUN
bjp-61292	248	3	regulators	regulator	NOUN
bjp-61292	248	4	of	of	ADP
bjp-61292	248	5	osteoclast	osteoclast	ADJ
bjp-61292	248	6	differentiation	differentiation	NOUN
bjp-61292	248	7	and	and	CCONJ
bjp-61292	248	8	cellcell	cellcell	ADJ
bjp-61292	248	9	fusion	fusion	NOUN
bjp-61292	248	10	.	.	PUNCT
bjp-61292	249	1	keio	keio	PROPN
bjp-61292	249	2	j	j	PROPN
bjp-61292	249	3	med	med	PROPN
bjp-61292	249	4	.	.	PUNCT
bjp-61292	249	5	2011	2011	NUM
bjp-61292	249	6	;	;	PUNCT
bjp-61292	249	7	60	60	NUM
bjp-61292	249	8	:	:	SYM
bjp-61292	249	9	101	101	NUM
bjp-61292	249	10	-	-	SYM
bjp-61292	249	11	05	05	NUM
bjp-61292	249	12	.	.	PUNCT
bjp-61292	250	1	mundy	mundy	PROPN
bjp-61292	250	2	gr	gr	PROPN
bjp-61292	250	3	.	.	PUNCT
bjp-61292	251	1	metastasis	metastasis	NOUN
bjp-61292	251	2	to	to	ADP
bjp-61292	251	3	bone	bone	NOUN
bjp-61292	251	4	:	:	PUNCT
bjp-61292	251	5	causes	cause	NOUN
bjp-61292	251	6	,	,	PUNCT
bjp-61292	251	7	consequences	consequence	NOUN
bjp-61292	251	8	and	and	CCONJ
bjp-61292	251	9	therapeutic	therapeutic	ADJ
bjp-61292	251	10	opportunities	opportunity	NOUN
bjp-61292	251	11	.	.	PUNCT
bjp-61292	252	1	nat	nat	PROPN
bjp-61292	252	2	rev	rev	PROPN
bjp-61292	252	3	cancer	cancer	NOUN
bjp-61292	252	4	.	.	PUNCT
bjp-61292	253	1	2002	2002	NUM
bjp-61292	253	2	;	;	PUNCT
bjp-61292	253	3	2	2	NUM
bjp-61292	253	4	:	:	PUNCT
bjp-61292	253	5	584	584	NUM
bjp-61292	253	6	-	-	SYM
bjp-61292	253	7	93	93	NUM
bjp-61292	253	8	.	.	PUNCT
bjp-61292	254	1	ohno	ohno	PROPN
bjp-61292	254	2	si	si	PROPN
bjp-61292	254	3	,	,	PUNCT
bjp-61292	254	4	takanashi	takanashi	PROPN
bjp-61292	254	5	m	m	PROPN
bjp-61292	254	6	,	,	PUNCT
bjp-61292	254	7	sudo	sudo	PROPN
bjp-61292	254	8	k	k	X
bjp-61292	254	9	,	,	PUNCT
bjp-61292	254	10	ueda	ueda	PROPN
bjp-61292	254	11	s	s	PROPN
bjp-61292	254	12	,	,	PUNCT
bjp-61292	254	13	ishikawa	ishikawa	PROPN
bjp-61292	254	14	a	a	X
bjp-61292	254	15	,	,	PUNCT
bjp-61292	254	16	matsuyama	matsuyama	PROPN
bjp-61292	254	17	n	n	CCONJ
bjp-61292	254	18	,	,	PUNCT
bjp-61292	254	19	fujita	fujita	PROPN
bjp-61292	254	20	k	k	PROPN
bjp-61292	254	21	,	,	PUNCT
bjp-61292	254	22	mizutani	mizutani	PROPN
bjp-61292	254	23	t	t	PROPN
bjp-61292	254	24	,	,	PUNCT
bjp-61292	254	25	ohgi	ohgi	PROPN
bjp-61292	254	26	t	t	PROPN
bjp-61292	254	27	,	,	PUNCT
bjp-61292	254	28	ochiya	ochiya	PROPN
bjp-61292	254	29	t	t	PROPN
bjp-61292	254	30	,	,	PUNCT
bjp-61292	254	31	gotoh	gotoh	PROPN
bjp-61292	254	32	n	n	CCONJ
bjp-61292	254	33	,	,	PUNCT
bjp-61292	254	34	kuroda	kuroda	PROPN
bjp-61292	254	35	m.	m.	PROPN
bjp-61292	254	36	systemically	systemically	ADV
bjp-61292	254	37	injected	inject	VERB
bjp-61292	254	38	exosomes	exosome	NOUN
bjp-61292	254	39	targeted	target	VERB
bjp-61292	254	40	to	to	PART
bjp-61292	254	41	egfr	egfr	ADV
bjp-61292	254	42	deliver	deliver	VERB
bjp-61292	254	43	antitumor	antitumor	PROPN
bjp-61292	254	44	microrna	microrna	PROPN
bjp-61292	254	45	to	to	ADP
bjp-61292	254	46	breast	breast	NOUN
bjp-61292	254	47	cancer	cancer	NOUN
bjp-61292	254	48	cells	cell	NOUN
bjp-61292	254	49	.	.	PUNCT
bjp-61292	255	1	mol	mol	ADP
bjp-61292	255	2	ther	ther	ADV
bjp-61292	255	3	.	.	PUNCT
bjp-61292	256	1	2013	2013	NUM
bjp-61292	256	2	;	;	PUNCT
bjp-61292	256	3	21	21	NUM
bjp-61292	256	4	:	:	SYM
bjp-61292	256	5	185	185	NUM
bjp-61292	256	6	-	-	SYM
bjp-61292	256	7	91	91	NUM
bjp-61292	256	8	.	.	PUNCT
bjp-61292	257	1	polyzos	polyzos	PROPN
bjp-61292	257	2	sa	sa	PROPN
bjp-61292	257	3	,	,	PUNCT
bjp-61292	257	4	anastasilakis	anastasilakis	PROPN
bjp-61292	257	5	ad	ad	NOUN
bjp-61292	257	6	,	,	PUNCT
bjp-61292	257	7	efstathiadou	efstathiadou	PROPN
bjp-61292	257	8	z	z	PROPN
bjp-61292	257	9	,	,	PUNCT
bjp-61292	257	10	kita	kita	PROPN
bjp-61292	257	11	m	m	PROPN
bjp-61292	257	12	,	,	PUNCT
bjp-61292	257	13	litsas	litsas	PROPN
bjp-61292	257	14	i	i	PROPN
bjp-61292	257	15	,	,	PUNCT
bjp-61292	257	16	avramidis	avramidis	PROPN
bjp-61292	257	17	a	a	PRON
bjp-61292	257	18	,	,	PUNCT
bjp-61292	257	19	arsos	arsos	NOUN
bjp-61292	257	20	g	g	NOUN
bjp-61292	257	21	,	,	PUNCT
bjp-61292	257	22	moralidis	moralidi	NOUN
bjp-61292	257	23	e	e	NOUN
bjp-61292	257	24	,	,	PUNCT
bjp-61292	257	25	gerou	gerou	PROPN
bjp-61292	257	26	s	s	PROPN
bjp-61292	257	27	,	,	PUNCT
bjp-61292	257	28	pavlidou	pavlidou	NOUN
bjp-61292	257	29	v	v	NOUN
bjp-61292	257	30	,	,	PUNCT
bjp-61292	257	31	papatheodorou	papatheodorou	ADJ
bjp-61292	257	32	a.	a.	NOUN
bjp-61292	257	33	the	the	DET
bjp-61292	257	34	effect	effect	NOUN
bjp-61292	257	35	of	of	ADP
bjp-61292	257	36	zoledronic	zoledronic	ADJ
bjp-61292	257	37	acid	acid	NOUN
bjp-61292	257	38	on	on	ADP
bjp-61292	257	39	serum	serum	NOUN
bjp-61292	257	40	dickkopf-1	dickkopf-1	PROPN
bjp-61292	257	41	,	,	PUNCT
bjp-61292	257	42	osteoprotegerin	osteoprotegerin	NOUN
bjp-61292	257	43	,	,	PUNCT
bjp-61292	257	44	and	and	CCONJ
bjp-61292	257	45	rankl	rankl	VERB
bjp-61292	257	46	in	in	ADP
bjp-61292	257	47	patients	patient	NOUN
bjp-61292	257	48	with	with	ADP
bjp-61292	257	49	paget	paget	PROPN
bjp-61292	257	50	's	's	PART
bjp-61292	257	51	disease	disease	NOUN
bjp-61292	257	52	of	of	ADP
bjp-61292	257	53	bone	bone	NOUN
bjp-61292	257	54	.	.	PUNCT
bjp-61292	258	1	horm	horm	PROPN
bjp-61292	258	2	metab	metab	PROPN
bjp-61292	258	3	res	re	NOUN
bjp-61292	258	4	.	.	PUNCT
bjp-61292	258	5	2009	2009	NUM
bjp-61292	258	6	;	;	PUNCT
bjp-61292	258	7	41	41	NUM
bjp-61292	258	8	:	:	SYM
bjp-61292	258	9	846	846	NUM
bjp-61292	258	10	-	-	SYM
bjp-61292	258	11	50	50	NUM
bjp-61292	258	12	.	.	PUNCT
bjp-61292	259	1	qiang	qiang	PROPN
bjp-61292	259	2	yw	yw	PROPN
bjp-61292	259	3	,	,	PUNCT
bjp-61292	259	4	chen	chen	PROPN
bjp-61292	259	5	y	y	PROPN
bjp-61292	259	6	,	,	PUNCT
bjp-61292	259	7	brown	brown	PROPN
bjp-61292	259	8	n	n	CCONJ
bjp-61292	259	9	,	,	PUNCT
bjp-61292	259	10	hu	hu	PROPN
bjp-61292	259	11	b	b	PROPN
bjp-61292	259	12	,	,	PUNCT
bjp-61292	259	13	epstein	epstein	PROPN
bjp-61292	259	14	j	j	PROPN
bjp-61292	259	15	,	,	PUNCT
bjp-61292	259	16	barlogie	barlogie	PROPN
bjp-61292	259	17	b	b	PROPN
bjp-61292	259	18	,	,	PUNCT
bjp-61292	259	19	shaughnessy	shaughnessy	PROPN
bjp-61292	259	20	jr	jr	PROPN
bjp-61292	259	21	jd	jd	PROPN
bjp-61292	259	22	.	.	PROPN
bjp-61292	259	23	characterization	characterization	NOUN
bjp-61292	259	24	of	of	ADP
bjp-61292	259	25	wnt	wnt	PROPN
bjp-61292	259	26	/	/	SYM
bjp-61292	259	27	beta	beta	NOUN
bjp-61292	259	28	-	-	PUNCT
bjp-61292	259	29	catenin	catenin	NOUN
bjp-61292	259	30	signalling	signal	VERB
bjp-61292	259	31	in	in	ADP
bjp-61292	259	32	osteoclasts	osteoclast	NOUN
bjp-61292	259	33	in	in	ADP
bjp-61292	259	34	multiple	multiple	ADJ
bjp-61292	259	35	myeloma	myeloma	NOUN
bjp-61292	259	36	.	.	PUNCT
bjp-61292	260	1	br	br	PROPN
bjp-61292	260	2	j	j	PROPN
bjp-61292	260	3	haematol	haematol	NOUN
bjp-61292	260	4	.	.	PUNCT
bjp-61292	261	1	2010	2010	NUM
bjp-61292	261	2	;	;	PUNCT
bjp-61292	261	3	148	148	NUM
bjp-61292	261	4	:	:	PUNCT
bjp-61292	261	5	726	726	NUM
bjp-61292	261	6	-	-	SYM
bjp-61292	261	7	38	38	NUM
bjp-61292	261	8	.	.	PUNCT
bjp-61292	262	1	rabinowits	rabinowit	NOUN
bjp-61292	262	2	g	g	PROPN
bjp-61292	262	3	,	,	PUNCT
bjp-61292	262	4	gerçel	gerçel	PROPN
bjp-61292	262	5	-	-	PROPN
bjp-61292	262	6	taylor	taylor	PROPN
bjp-61292	262	7	c	c	PROPN
bjp-61292	262	8	,	,	PUNCT
bjp-61292	262	9	day	day	PROPN
bjp-61292	262	10	jm	jm	PROPN
bjp-61292	262	11	,	,	PUNCT
bjp-61292	262	12	taylor	taylor	PROPN
bjp-61292	262	13	dd	dd	PROPN
bjp-61292	262	14	,	,	PUNCT
bjp-61292	262	15	kloecker	kloecker	PROPN
bjp-61292	262	16	gh	gh	PROPN
bjp-61292	262	17	.	.	PROPN
bjp-61292	263	1	exosomal	exosomal	PROPN
bjp-61292	263	2	microrna	microrna	PROPN
bjp-61292	263	3	:	:	PUNCT
bjp-61292	263	4	a	a	DET
bjp-61292	263	5	diagnostic	diagnostic	ADJ
bjp-61292	263	6	marker	marker	NOUN
bjp-61292	263	7	for	for	ADP
bjp-61292	263	8	lung	lung	NOUN
bjp-61292	263	9	cancer	cancer	NOUN
bjp-61292	263	10	.	.	PUNCT
bjp-61292	264	1	clin	clin	PROPN
bjp-61292	264	2	lung	lung	PROPN
bjp-61292	264	3	cancer	cancer	NOUN
bjp-61292	264	4	.	.	PUNCT
bjp-61292	265	1	2009	2009	NUM
bjp-61292	265	2	;	;	PUNCT
bjp-61292	265	3	10	10	NUM
bjp-61292	265	4	:	:	SYM
bjp-61292	265	5	42	42	NUM
bjp-61292	265	6	-	-	SYM
bjp-61292	265	7	46	46	NUM
bjp-61292	265	8	.	.	PUNCT
bjp-61292	266	1	ren	ren	PROPN
bjp-61292	266	2	d	d	PROPN
bjp-61292	266	3	,	,	PUNCT
bjp-61292	266	4	yang	yang	PROPN
bjp-61292	266	5	q	q	PROPN
bjp-61292	266	6	,	,	PUNCT
bjp-61292	266	7	dai	dai	PROPN
bjp-61292	266	8	y	y	PROPN
bjp-61292	266	9	,	,	PUNCT
bjp-61292	266	10	guo	guo	PROPN
bjp-61292	266	11	w	w	PROPN
bjp-61292	266	12	,	,	PUNCT
bjp-61292	266	13	du	du	PROPN
bjp-61292	266	14	h	h	NOUN
bjp-61292	266	15	,	,	PUNCT
bjp-61292	266	16	song	song	PROPN
bjp-61292	266	17	l	l	PROPN
bjp-61292	266	18	,	,	PUNCT
bjp-61292	266	19	peng	peng	PROPN
bjp-61292	266	20	x.	x.	PROPN
bjp-61292	266	21	oncogenic	oncogenic	PROPN
bjp-61292	266	22	mir-210	mir-210	PROPN
bjp-61292	266	23	-	-	PUNCT
bjp-61292	266	24	3p	3p	NUM
bjp-61292	266	25	promotes	promote	VERB
bjp-61292	266	26	prostate	prostate	NOUN
bjp-61292	266	27	cancer	cancer	NOUN
bjp-61292	266	28	cell	cell	NOUN
bjp-61292	266	29	emt	emt	NOUN
bjp-61292	266	30	and	and	CCONJ
bjp-61292	266	31	bone	bone	NOUN
bjp-61292	266	32	metastasis	metastasis	NOUN
bjp-61292	266	33	via	via	ADP
bjp-61292	266	34	nf	nf	NOUN
bjp-61292	266	35	-	-	PUNCT
bjp-61292	266	36	kappab	kappab	NOUN
bjp-61292	266	37	signaling	signal	VERB
bjp-61292	266	38	pathway	pathway	NOUN
bjp-61292	266	39	.	.	PUNCT
bjp-61292	267	1	mol	mol	ADP
bjp-61292	267	2	cancer	cancer	NOUN
bjp-61292	267	3	.	.	PUNCT
bjp-61292	268	1	2017	2017	NUM
bjp-61292	268	2	;	;	PUNCT
bjp-61292	268	3	16	16	NUM
bjp-61292	268	4	:	:	SYM
bjp-61292	268	5	117	117	NUM
bjp-61292	268	6	.	.	PUNCT
bjp-61292	269	1	song	song	PROPN
bjp-61292	269	2	c	c	PROPN
bjp-61292	269	3	,	,	PUNCT
bjp-61292	269	4	yang	yang	PROPN
bjp-61292	269	5	x	x	PROPN
bjp-61292	269	6	,	,	PUNCT
bjp-61292	269	7	lei	lei	PROPN
bjp-61292	269	8	y	y	PROPN
bjp-61292	269	9	,	,	PUNCT
bjp-61292	269	10	zhang	zhang	PROPN
bjp-61292	269	11	z	z	PROPN
bjp-61292	269	12	,	,	PUNCT
bjp-61292	269	13	smith	smith	PROPN
bjp-61292	269	14	w	w	PROPN
bjp-61292	269	15	,	,	PUNCT
bjp-61292	269	16	yan	yan	PROPN
bjp-61292	269	17	j	j	PROPN
bjp-61292	269	18	,	,	PUNCT
bjp-61292	269	19	kong	kong	PROPN
bjp-61292	269	20	l.	l.	PROPN
bjp-61292	269	21	evaluation	evaluation	NOUN
bjp-61292	269	22	of	of	ADP
bjp-61292	269	23	efficacy	efficacy	NOUN
bjp-61292	269	24	on	on	ADP
bjp-61292	269	25	rankl	rankl	PROPN
bjp-61292	269	26	induced	induce	VERB
bjp-61292	269	27	osteoclast	osteoclast	ADV
bjp-61292	269	28	from	from	ADP
bjp-61292	269	29	raw264	raw264	PROPN
bjp-61292	269	30	.	.	PROPN
bjp-61292	269	31	7	7	NUM
bjp-61292	269	32	cells	cell	NOUN
bjp-61292	269	33	.	.	PUNCT
bjp-61292	270	1	j	j	PROPN
bjp-61292	270	2	cell	cell	NOUN
bjp-61292	270	3	physiol	physiol	PROPN
bjp-61292	270	4	.	.	PUNCT
bjp-61292	271	1	2019	2019	NUM
bjp-61292	271	2	;	;	PUNCT
bjp-61292	271	3	234	234	NUM
bjp-61292	271	4	:	:	SYM
bjp-61292	271	5	11969	11969	NUM
bjp-61292	271	6	-	-	SYM
bjp-61292	271	7	75	75	NUM
bjp-61292	271	8	.	.	PUNCT
bjp-61292	272	1	spencer	spencer	PROPN
bjp-61292	272	2	gj	gj	PROPN
bjp-61292	272	3	,	,	PUNCT
bjp-61292	272	4	utting	utte	VERB
bjp-61292	272	5	jc	jc	PROPN
bjp-61292	272	6	,	,	PUNCT
bjp-61292	272	7	etheridge	etheridge	PROPN
bjp-61292	272	8	sl	sl	PROPN
bjp-61292	272	9	,	,	PUNCT
bjp-61292	272	10	arnett	arnett	PROPN
bjp-61292	272	11	tr	tr	VERB
bjp-61292	272	12	,	,	PUNCT
bjp-61292	272	13	genever	genever	PROPN
bjp-61292	272	14	pg	pg	VERB
bjp-61292	272	15	.	.	PUNCT
bjp-61292	273	1	wnt	wnt	NOUN
bjp-61292	273	2	signalling	signal	VERB
bjp-61292	273	3	in	in	ADP
bjp-61292	273	4	osteoblasts	osteoblast	NOUN
bjp-61292	273	5	regulates	regulate	VERB
bjp-61292	273	6	expression	expression	NOUN
bjp-61292	273	7	of	of	ADP
bjp-61292	273	8	the	the	DET
bjp-61292	273	9	receptor	receptor	NOUN
bjp-61292	273	10	activator	activator	NOUN
bjp-61292	273	11	of	of	ADP
bjp-61292	273	12	nfkappab	nfkappab	NOUN
bjp-61292	273	13	ligand	ligand	NOUN
bjp-61292	273	14	and	and	CCONJ
bjp-61292	273	15	inhibits	inhibit	VERB
bjp-61292	273	16	osteoclastogenesis	osteoclastogenesis	NOUN
bjp-61292	273	17	in	in	ADP
bjp-61292	273	18	vitro	vitro	X
bjp-61292	273	19	.	.	PUNCT
bjp-61292	274	1	j	j	PROPN
bjp-61292	274	2	cell	cell	PROPN
bjp-61292	274	3	sci	sci	PROPN
bjp-61292	274	4	.	.	PROPN
bjp-61292	274	5	2006	2006	NUM
bjp-61292	274	6	;	;	PUNCT
bjp-61292	274	7	119	119	NUM
bjp-61292	274	8	:	:	SYM
bjp-61292	274	9	1283	1283	NUM
bjp-61292	274	10	-	-	SYM
bjp-61292	274	11	96	96	NUM
bjp-61292	274	12	.	.	PUNCT
bjp-61292	275	1	weilbaecher	weilbaecher	PROPN
bjp-61292	275	2	kn	kn	PROPN
bjp-61292	275	3	,	,	PUNCT
bjp-61292	275	4	guise	guise	ADJ
bjp-61292	275	5	ta	ta	ADP
bjp-61292	275	6	,	,	PUNCT
bjp-61292	275	7	mccauley	mccauley	PROPN
bjp-61292	275	8	lk	lk	PROPN
bjp-61292	275	9	.	.	PROPN
bjp-61292	275	10	cancer	cancer	NOUN
bjp-61292	275	11	to	to	ADP
bjp-61292	275	12	bone	bone	NOUN
bjp-61292	275	13	:	:	PUNCT
bjp-61292	275	14	a	a	DET
bjp-61292	275	15	fatal	fatal	ADJ
bjp-61292	275	16	attraction	attraction	NOUN
bjp-61292	275	17	.	.	PUNCT
bjp-61292	276	1	nat	nat	PROPN
bjp-61292	276	2	rev	rev	PROPN
bjp-61292	276	3	cancer	cancer	NOUN
bjp-61292	276	4	.	.	PUNCT
bjp-61292	277	1	2011	2011	NUM
bjp-61292	277	2	;	;	PUNCT
bjp-61292	277	3	11	11	NUM
bjp-61292	277	4	:	:	PUNCT
bjp-61292	277	5	411	411	NUM
bjp-61292	277	6	-	-	SYM
bjp-61292	277	7	25	25	NUM
bjp-61292	277	8	.	.	PUNCT
bjp-61292	277	9	yan	yan	PROPN
bjp-61292	278	1	w	w	PROPN
bjp-61292	278	2	,	,	PUNCT
bjp-61292	278	3	ma	ma	PROPN
bjp-61292	278	4	x	x	PROPN
bjp-61292	278	5	,	,	PUNCT
bjp-61292	278	6	zhao	zhao	PROPN
bjp-61292	278	7	x	x	PROPN
bjp-61292	278	8	,	,	PUNCT
bjp-61292	278	9	zhang	zhang	PROPN
bjp-61292	278	10	s.	s.	PROPN
bjp-61292	278	11	baicalein	baicalein	PROPN
bjp-61292	278	12	induces	induce	VERB
bjp-61292	278	13	apoptosis	apoptosis	NOUN
bjp-61292	278	14	and	and	CCONJ
bjp-61292	278	15	autophagy	autophagy	NOUN
bjp-61292	278	16	of	of	ADP
bjp-61292	278	17	breast	breast	NOUN
bjp-61292	278	18	cancer	cancer	NOUN
bjp-61292	278	19	cells	cell	NOUN
bjp-61292	278	20	via	via	ADP
bjp-61292	278	21	inhibiting	inhibit	VERB
bjp-61292	278	22	pi3k/	pi3k/	NOUN
bjp-61292	278	23	akt	akt	PROPN
bjp-61292	278	24	pathway	pathway	NOUN
bjp-61292	278	25	in	in	ADP
bjp-61292	278	26	vivo	vivo	NOUN
bjp-61292	278	27	and	and	CCONJ
bjp-61292	278	28	vitro	vitro	X
bjp-61292	278	29	.	.	PUNCT
bjp-61292	279	1	drug	drug	NOUN
bjp-61292	279	2	des	des	PROPN
bjp-61292	279	3	devel	devel	NOUN
bjp-61292	279	4	ther	ther	ADV
bjp-61292	279	5	.	.	PUNCT
bjp-61292	280	1	2018	2018	NUM
bjp-61292	280	2	,	,	PUNCT
bjp-61292	280	3	12	12	NUM
bjp-61292	280	4	:	:	SYM
bjp-61292	280	5	3961	3961	NUM
bjp-61292	280	6	.	.	PUNCT
bjp-61292	281	1	yang	yang	PROPN
bjp-61292	281	2	ss	ss	PROPN
bjp-61292	281	3	,	,	PUNCT
bjp-61292	281	4	ma	ma	PROPN
bjp-61292	281	5	s	s	PROPN
bjp-61292	281	6	,	,	PUNCT
bjp-61292	281	7	dou	dou	PROPN
bjp-61292	281	8	h	h	NOUN
bjp-61292	281	9	,	,	PUNCT
bjp-61292	281	10	liu	liu	PROPN
bjp-61292	281	11	f	f	PROPN
bjp-61292	281	12	,	,	PUNCT
bjp-61292	281	13	zhang	zhang	PROPN
bjp-61292	281	14	sy	sy	PROPN
bjp-61292	281	15	,	,	PUNCT
bjp-61292	281	16	jiang	jiang	PROPN
bjp-61292	281	17	c	c	PROPN
bjp-61292	281	18	,	,	PUNCT
bjp-61292	281	19	xiao	xiao	PROPN
bjp-61292	281	20	m	m	PROPN
bjp-61292	281	21	,	,	PUNCT
bjp-61292	281	22	huang	huang	PROPN
bjp-61292	281	23	yx	yx	PROPN
bjp-61292	281	24	.	.	PROPN
bjp-61292	281	25	breast	breast	NOUN
bjp-61292	281	26	cancer	cancer	NOUN
bjp-61292	281	27	-	-	PUNCT
bjp-61292	281	28	derived	derive	VERB
bjp-61292	281	29	exosomes	exosome	NOUN
bjp-61292	281	30	regulate	regulate	VERB
bjp-61292	281	31	cell	cell	NOUN
bjp-61292	281	32	invasion	invasion	NOUN
bjp-61292	281	33	and	and	CCONJ
bjp-61292	281	34	metastasis	metastasis	NOUN
bjp-61292	281	35	in	in	ADP
bjp-61292	281	36	breast	breast	NOUN
bjp-61292	281	37	cancer	cancer	NOUN
bjp-61292	281	38	via	via	ADP
bjp-61292	281	39	mir-146a	mir-146a	NUM
bjp-61292	281	40	to	to	PART
bjp-61292	281	41	activate	activate	VERB
bjp-61292	281	42	cancer	cancer	NOUN
bjp-61292	281	43	associated	associate	VERB
bjp-61292	281	44	fibroblasts	fibroblast	NOUN
bjp-61292	281	45	in	in	ADP
bjp-61292	281	46	tumor	tumor	NOUN
bjp-61292	281	47	microenvironment	microenvironment	NOUN
bjp-61292	281	48	.	.	PUNCT
bjp-61292	282	1	exp	exp	NOUN
bjp-61292	282	2	cell	cell	NOUN
bjp-61292	282	3	res	re	NOUN
bjp-61292	282	4	.	.	PUNCT
bjp-61292	283	1	2020	2020	NUM
bjp-61292	283	2	,	,	PUNCT
bjp-61292	283	3	391	391	NUM
bjp-61292	283	4	:	:	SYM
bjp-61292	283	5	111983	111983	NUM
bjp-61292	283	6	.	.	PUNCT
bjp-61292	284	1	yuan	yuan	NOUN
bjp-61292	284	2	x	x	SYM
bjp-61292	284	3	,	,	PUNCT
bjp-61292	284	4	qian	qian	PROPN
bjp-61292	284	5	n	n	CCONJ
bjp-61292	284	6	,	,	PUNCT
bjp-61292	284	7	ling	ling	PROPN
bjp-61292	284	8	s	s	PROPN
bjp-61292	284	9	,	,	PUNCT
bjp-61292	284	10	li	li	PROPN
bjp-61292	284	11	y	y	PROPN
bjp-61292	284	12	,	,	PUNCT
bjp-61292	284	13	sun	sun	PROPN
bjp-61292	284	14	w	w	PROPN
bjp-61292	284	15	,	,	PUNCT
bjp-61292	284	16	li	li	PROPN
bjp-61292	284	17	j	j	PROPN
bjp-61292	284	18	,	,	PUNCT
bjp-61292	284	19	du	du	PROPN
bjp-61292	284	20	r	r	PROPN
bjp-61292	284	21	,	,	PUNCT
bjp-61292	284	22	zhong	zhong	PROPN
bjp-61292	284	23	g	g	PROPN
bjp-61292	284	24	,	,	PUNCT
bjp-61292	284	25	liu	liu	PROPN
bjp-61292	284	26	c	c	PROPN
bjp-61292	284	27	,	,	PUNCT
bjp-61292	284	28	yu	yu	PROPN
bjp-61292	284	29	g	g	PROPN
bjp-61292	284	30	,	,	PUNCT
bjp-61292	284	31	cao	cao	PROPN
bjp-61292	284	32	d.	d.	PROPN
bjp-61292	284	33	breast	breast	PROPN
bjp-61292	284	34	cancer	cancer	NOUN
bjp-61292	284	35	exosomes	exosome	NOUN
bjp-61292	284	36	contribute	contribute	VERB
bjp-61292	284	37	to	to	ADP
bjp-61292	284	38	premetastatic	premetastatic	ADJ
bjp-61292	284	39	niche	niche	NOUN
bjp-61292	284	40	formation	formation	NOUN
bjp-61292	284	41	and	and	CCONJ
bjp-61292	284	42	promote	promote	VERB
bjp-61292	284	43	bone	bone	NOUN
bjp-61292	284	44	metastasis	metastasis	NOUN
bjp-61292	284	45	of	of	ADP
bjp-61292	284	46	tumor	tumor	NOUN
bjp-61292	284	47	cells	cell	NOUN
bjp-61292	284	48	.	.	PUNCT
bjp-61292	285	1	theranostics	theranostic	NOUN
bjp-61292	285	2	2021	2021	NUM
bjp-61292	285	3	;	;	PUNCT
bjp-61292	285	4	11	11	NUM
bjp-61292	285	5	:	:	SYM
bjp-61292	285	6	1429	1429	NUM
bjp-61292	285	7	-	-	SYM
bjp-61292	285	8	45	45	NUM
bjp-61292	285	9	.	.	PUNCT
bjp-61292	286	1	zhang	zhang	PROPN
bjp-61292	286	2	x	x	PROPN
bjp-61292	286	3	,	,	PUNCT
bjp-61292	286	4	yuan	yuan	PROPN
bjp-61292	286	5	x	x	SYM
bjp-61292	286	6	,	,	PUNCT
bjp-61292	286	7	shi	shi	PROPN
bjp-61292	286	8	h	h	PROPN
bjp-61292	286	9	,	,	PUNCT
bjp-61292	286	10	wu	wu	PROPN
bjp-61292	286	11	l	l	PROPN
bjp-61292	286	12	,	,	PUNCT
bjp-61292	286	13	qian	qian	PROPN
bjp-61292	286	14	h	h	PROPN
bjp-61292	286	15	,	,	PUNCT
bjp-61292	286	16	xu	xu	PROPN
bjp-61292	286	17	w.	w.	PROPN
bjp-61292	286	18	exosomes	exosome	NOUN
bjp-61292	286	19	in	in	ADP
bjp-61292	286	20	cancer	cancer	NOUN
bjp-61292	286	21	:	:	PUNCT
bjp-61292	286	22	small	small	ADJ
bjp-61292	286	23	particle	particle	NOUN
bjp-61292	286	24	,	,	PUNCT
bjp-61292	286	25	big	big	ADJ
bjp-61292	286	26	player	player	NOUN
bjp-61292	286	27	.	.	PUNCT
bjp-61292	287	1	j	j	PROPN
bjp-61292	287	2	hematol	hematol	PROPN
bjp-61292	287	3	oncol	oncol	ADJ
bjp-61292	287	4	.	.	PUNCT
bjp-61292	288	1	2015	2015	NUM
bjp-61292	288	2	;	;	PUNCT
bjp-61292	288	3	8	8	NUM
bjp-61292	288	4	:	:	SYM
bjp-61292	288	5	83	83	NUM
bjp-61292	288	6	.	.	PUNCT
bjp-61292	289	1	zhou	zhou	PROPN
bjp-61292	289	2	y	y	PROPN
bjp-61292	289	3	,	,	PUNCT
bjp-61292	289	4	wang	wang	PROPN
bjp-61292	289	5	l	l	PROPN
bjp-61292	289	6	,	,	PUNCT
bjp-61292	289	7	lin	lin	PROPN
bjp-61292	289	8	h	h	PROPN
bjp-61292	289	9	,	,	PUNCT
bjp-61292	289	10	wang	wang	PROPN
bjp-61292	289	11	y	y	PROPN
bjp-61292	289	12	,	,	PUNCT
bjp-61292	289	13	hou	hou	PROPN
bjp-61292	289	14	k.	k.	PROPN
bjp-61292	289	15	bufalin	bufalin	PROPN
bjp-61292	289	16	inhibits	inhibit	VERB
bjp-61292	289	17	the	the	DET
bjp-61292	289	18	growth	growth	NOUN
bjp-61292	289	19	and	and	CCONJ
bjp-61292	289	20	epithelial	epithelial	ADJ
bjp-61292	289	21	to	to	ADP
bjp-61292	289	22	mesenchymal	mesenchymal	ADJ
bjp-61292	289	23	transition	transition	NOUN
bjp-61292	289	24	of	of	ADP
bjp-61292	289	25	human	human	ADJ
bjp-61292	289	26	gastric	gastric	ADJ
bjp-61292	289	27	cancer	cancer	NOUN
bjp-61292	289	28	cells	cell	NOUN
bjp-61292	289	29	via	via	ADP
bjp-61292	289	30	modulation	modulation	NOUN
bjp-61292	289	31	of	of	ADP
bjp-61292	289	32	mek	mek	PROPN
bjp-61292	289	33	/	/	SYM
bjp-61292	289	34	erk	erk	PROPN
bjp-61292	289	35	pathway	pathway	NOUN
bjp-61292	289	36	.	.	PUNCT
bjp-61292	290	1	bangladesh	bangladesh	PROPN
bjp-61292	290	2	j	j	PROPN
bjp-61292	290	3	pharmacol	pharmacol	PROPN
bjp-61292	290	4	.	.	PROPN
bjp-61292	291	1	2021	2021	NUM
bjp-61292	291	2	,	,	PUNCT
bjp-61292	291	3	16	16	NUM
bjp-61292	291	4	:	:	SYM
bjp-61292	291	5	27	27	NUM
bjp-61292	291	6	-	-	SYM
bjp-61292	291	7	33	33	NUM
bjp-61292	291	8	.	.	PUNCT
bjp-61292	292	1	bangladesh	bangladesh	PROPN
bjp-61292	292	2	j	j	PROPN
bjp-61292	292	3	pharmacol	pharmacol	PROPN
bjp-61292	292	4	2022	2022	NUM
bjp-61292	292	5	;	;	PUNCT
bjp-61292	292	6	17	17	NUM
bjp-61292	292	7	:	:	SYM
bjp-61292	292	8	92	92	NUM
bjp-61292	292	9	-	-	SYM
bjp-61292	292	10	101	101	NUM
bjp-61292	292	11	101	101	NUM