id	sid	tid	token	lemma	pos
bjp-62725	1	1	bangladesh	bangladesh	PROPN
bjp-62725	1	2	journal	journal	PROPN
bjp-62725	1	3	of	of	ADP
bjp-62725	1	4	pharmacology	pharmacology	NOUN
bjp-62725	1	5	research	research	NOUN
bjp-62725	1	6	article	article	NOUN
bjp-62725	1	7	destabilising	destabilising	ADJ
bjp-62725	1	8	microtubule	microtubule	NOUN
bjp-62725	1	9	polymerization	polymerization	NOUN
bjp-62725	1	10	regulates	regulate	VERB
bjp-62725	1	11	chondrocyte	chondrocyte	PROPN
bjp-62725	1	12	dedifferentiation	dedifferentiation	NOUN
bjp-62725	1	13	and	and	CCONJ
bjp-62725	1	14	inflammation	inflammation	NOUN
bjp-62725	1	15	via	via	ADP
bjp-62725	1	16	nuclear	nuclear	ADJ
bjp-62725	1	17	factor	factor	NOUN
bjp-62725	1	18	kappa	kappa	PROPN
bjp-62725	1	19	b	b	PROPN
bjp-62725	1	20	and	and	CCONJ
bjp-62725	1	21	β	β	NOUN
bjp-62725	1	22	-	-	ADJ
bjp-62725	1	23	catenin	catenin	ADJ
bjp-62725	1	24	pathway	pathway	NOUN
bjp-62725	1	25	bjp	bjp	NOUN
bjp-62725	1	26	introduction	introduction	NOUN
bjp-62725	1	27	one	one	NUM
bjp-62725	1	28	of	of	ADP
bjp-62725	1	29	the	the	DET
bjp-62725	1	30	most	most	ADV
bjp-62725	1	31	common	common	ADJ
bjp-62725	1	32	painful	painful	ADJ
bjp-62725	1	33	and	and	CCONJ
bjp-62725	1	34	incapacitating	incapacitate	VERB
bjp-62725	1	35	chronic	chronic	ADJ
bjp-62725	1	36	degenerative	degenerative	ADJ
bjp-62725	1	37	joint	joint	ADJ
bjp-62725	1	38	illnesses	illness	NOUN
bjp-62725	1	39	worldwide	worldwide	ADV
bjp-62725	1	40	is	be	AUX
bjp-62725	1	41	osteoarthritis	osteoarthritis	NOUN
bjp-62725	1	42	.	.	PUNCT
bjp-62725	2	1	age	age	NOUN
bjp-62725	2	2	,	,	PUNCT
bjp-62725	2	3	weight	weight	NOUN
bjp-62725	2	4	,	,	PUNCT
bjp-62725	2	5	gender	gender	NOUN
bjp-62725	2	6	,	,	PUNCT
bjp-62725	2	7	dietary	dietary	ADJ
bjp-62725	2	8	habits	habit	NOUN
bjp-62725	2	9	,	,	PUNCT
bjp-62725	2	10	and	and	CCONJ
bjp-62725	2	11	joint	joint	ADJ
bjp-62725	2	12	injuries	injury	NOUN
bjp-62725	2	13	are	be	AUX
bjp-62725	2	14	a	a	DET
bjp-62725	2	15	few	few	ADJ
bjp-62725	2	16	examples	example	NOUN
bjp-62725	2	17	of	of	ADP
bjp-62725	2	18	risk	risk	NOUN
bjp-62725	2	19	factors	factor	NOUN
bjp-62725	2	20	for	for	ADP
bjp-62725	2	21	osteoarthritis	osteoarthritis	NOUN
bjp-62725	2	22	(	(	PUNCT
bjp-62725	2	23	whittaker	whittaker	PROPN
bjp-62725	2	24	et	et	PROPN
bjp-62725	2	25	al	al	PROPN
bjp-62725	2	26	.	.	PROPN
bjp-62725	2	27	,	,	PUNCT
bjp-62725	2	28	2021	2021	NUM
bjp-62725	2	29	)	)	PUNCT
bjp-62725	2	30	.	.	PUNCT
bjp-62725	3	1	however	however	ADV
bjp-62725	3	2	,	,	PUNCT
bjp-62725	3	3	there	there	PRON
bjp-62725	3	4	is	be	VERB
bjp-62725	3	5	still	still	ADV
bjp-62725	3	6	no	no	DET
bjp-62725	3	7	perfect	perfect	ADJ
bjp-62725	3	8	treatment	treatment	NOUN
bjp-62725	3	9	for	for	ADP
bjp-62725	3	10	osteoarthritis	osteoarthritis	NOUN
bjp-62725	3	11	,	,	PUNCT
bjp-62725	3	12	and	and	CCONJ
bjp-62725	3	13	the	the	DET
bjp-62725	3	14	molecular	molecular	ADJ
bjp-62725	3	15	mechanism	mechanism	NOUN
bjp-62725	3	16	is	be	AUX
bjp-62725	3	17	not	not	PART
bjp-62725	3	18	fully	fully	ADV
bjp-62725	3	19	understood	understand	VERB
bjp-62725	3	20	.	.	PUNCT
bjp-62725	4	1	understanding	understand	VERB
bjp-62725	4	2	the	the	DET
bjp-62725	4	3	molecular	molecular	ADJ
bjp-62725	4	4	pathways	pathway	NOUN
bjp-62725	4	5	governing	govern	VERB
bjp-62725	4	6	the	the	DET
bjp-62725	4	7	differentiation	differentiation	NOUN
bjp-62725	4	8	,	,	PUNCT
bjp-62725	4	9	dedifferentiation	dedifferentiation	NOUN
bjp-62725	4	10	,	,	PUNCT
bjp-62725	4	11	and	and	CCONJ
bjp-62725	4	12	inflammation	inflammation	NOUN
bjp-62725	4	13	of	of	ADP
bjp-62725	4	14	chondrocytes	chondrocyte	NOUN
bjp-62725	4	15	is	be	AUX
bjp-62725	4	16	essential	essential	ADJ
bjp-62725	4	17	for	for	ADP
bjp-62725	4	18	treating	treat	VERB
bjp-62725	4	19	osteoarthritis	osteoarthritis	NOUN
bjp-62725	4	20	.	.	PUNCT
bjp-62725	5	1	extracellular	extracellular	ADJ
bjp-62725	5	2	matrix	matrix	NOUN
bjp-62725	5	3	components	component	NOUN
bjp-62725	5	4	synthesized	synthesize	VERB
bjp-62725	5	5	by	by	ADP
bjp-62725	5	6	the	the	DET
bjp-62725	5	7	cartilage	cartilage	NOUN
bjp-62725	5	8	include	include	VERB
bjp-62725	5	9	collagen	collagen	NOUN
bjp-62725	5	10	,	,	PUNCT
bjp-62725	5	11	sulphated	sulphate	VERB
bjp-62725	5	12	-	-	PUNCT
bjp-62725	5	13	proteoglycan	proteoglycan	ADJ
bjp-62725	5	14	,	,	PUNCT
bjp-62725	5	15	hyaluronic	hyaluronic	ADJ
bjp-62725	5	16	acid	acid	NOUN
bjp-62725	5	17	,	,	PUNCT
bjp-62725	5	18	and	and	CCONJ
bjp-62725	5	19	glycoproteins	glycoprotein	NOUN
bjp-62725	5	20	which	which	PRON
bjp-62725	5	21	are	be	AUX
bjp-62725	5	22	expressed	express	VERB
bjp-62725	5	23	by	by	ADP
bjp-62725	5	24	various	various	ADJ
bjp-62725	5	25	cellular	cellular	ADJ
bjp-62725	5	26	regulatory	regulatory	ADJ
bjp-62725	5	27	signals	signal	NOUN
bjp-62725	5	28	stimulating	stimulate	VERB
bjp-62725	5	29	cartilagespecific	cartilagespecific	NOUN
bjp-62725	5	30	genes	gene	NOUN
bjp-62725	5	31	(	(	PUNCT
bjp-62725	5	32	shi	shi	PROPN
bjp-62725	5	33	et	et	PROPN
bjp-62725	5	34	al	al	PROPN
bjp-62725	5	35	.	.	PROPN
bjp-62725	5	36	,	,	PUNCT
bjp-62725	5	37	2019	2019	NUM
bjp-62725	5	38	;	;	PUNCT
bjp-62725	5	39	li	li	PROPN
bjp-62725	5	40	and	and	CCONJ
bjp-62725	5	41	wu	wu	PROPN
bjp-62725	5	42	,	,	PUNCT
bjp-62725	5	43	2021	2021	NUM
bjp-62725	5	44	;	;	PUNCT
bjp-62725	5	45	xiao	xiao	PROPN
bjp-62725	5	46	et	et	PROPN
bjp-62725	5	47	al	al	PROPN
bjp-62725	5	48	.	.	PROPN
bjp-62725	5	49	,	,	PUNCT
bjp-62725	5	50	2021	2021	NUM
bjp-62725	5	51	)	)	PUNCT
bjp-62725	5	52	.	.	PUNCT
bjp-62725	6	1	homeostatic	homeostatic	ADJ
bjp-62725	6	2	disruption	disruption	NOUN
bjp-62725	6	3	of	of	ADP
bjp-62725	6	4	extracellular	extracellular	ADJ
bjp-62725	6	5	matrix	matrix	NOUN
bjp-62725	6	6	expression	expression	NOUN
bjp-62725	6	7	in	in	ADP
bjp-62725	6	8	articular	articular	ADJ
bjp-62725	6	9	chondrocytes	chondrocyte	NOUN
bjp-62725	6	10	involves	involve	VERB
bjp-62725	6	11	loss	loss	NOUN
bjp-62725	6	12	of	of	ADP
bjp-62725	6	13	the	the	DET
bjp-62725	6	14	differentiated	differentiated	ADJ
bjp-62725	6	15	phenotype	phenotype	NOUN
bjp-62725	6	16	of	of	ADP
bjp-62725	6	17	chondrocytes	chondrocyte	NOUN
bjp-62725	6	18	during	during	ADP
bjp-62725	6	19	the	the	DET
bjp-62725	6	20	development	development	NOUN
bjp-62725	6	21	of	of	ADP
bjp-62725	6	22	cartilage	cartilage	NOUN
bjp-62725	6	23	diseases	disease	NOUN
bjp-62725	6	24	such	such	ADJ
bjp-62725	6	25	as	as	ADP
bjp-62725	6	26	osteoarthritis	osteoarthritis	NOUN
bjp-62725	6	27	(	(	PUNCT
bjp-62725	6	28	guo	guo	PROPN
bjp-62725	6	29	et	et	PROPN
bjp-62725	6	30	al	al	PROPN
bjp-62725	6	31	.	.	PROPN
bjp-62725	6	32	,	,	PUNCT
bjp-62725	6	33	2021	2021	NUM
bjp-62725	6	34	)	)	PUNCT
bjp-62725	6	35	.	.	PUNCT
bjp-62725	7	1	to	to	PART
bjp-62725	7	2	maintain	maintain	VERB
bjp-62725	7	3	homeostasis	homeostasis	NOUN
bjp-62725	7	4	,	,	PUNCT
bjp-62725	7	5	extracellular	extracellular	ADJ
bjp-62725	7	6	matrix	matrix	NOUN
bjp-62725	7	7	synthesis	synthesis	NOUN
bjp-62725	7	8	and	and	CCONJ
bjp-62725	7	9	breakdown	breakdown	NOUN
bjp-62725	7	10	must	must	AUX
bjp-62725	7	11	be	be	AUX
bjp-62725	7	12	strictly	strictly	ADV
bjp-62725	7	13	regulated	regulate	VERB
bjp-62725	7	14	numerous	numerous	ADJ
bjp-62725	7	15	elements	element	NOUN
bjp-62725	7	16	in	in	ADP
bjp-62725	7	17	the	the	DET
bjp-62725	7	18	chondrocytes	chondrocyte	NOUN
bjp-62725	7	19	'	'	PART
bjp-62725	7	20	chemical	chemical	ADJ
bjp-62725	7	21	and	and	CCONJ
bjp-62725	7	22	mechanical	mechanical	ADJ
bjp-62725	7	23	state	state	NOUN
bjp-62725	7	24	regulate	regulate	VERB
bjp-62725	7	25	their	their	PRON
bjp-62725	7	26	metabolic	metabolic	NOUN
bjp-62725	7	27	and	and	CCONJ
bjp-62725	7	28	anabolic	anabolic	NOUN
bjp-62725	7	29	activities	activity	NOUN
bjp-62725	7	30	(	(	PUNCT
bjp-62725	7	31	zheng	zheng	X
bjp-62725	7	32	et	et	PROPN
bjp-62725	7	33	al	al	PROPN
bjp-62725	7	34	.	.	PROPN
bjp-62725	7	35	,	,	PUNCT
bjp-62725	7	36	2021	2021	NUM
bjp-62725	7	37	;	;	PUNCT
bjp-62725	7	38	hodgkinson	hodgkinson	PROPN
bjp-62725	7	39	et	et	PROPN
bjp-62725	7	40	al	al	PROPN
bjp-62725	7	41	.	.	PROPN
bjp-62725	7	42	,	,	PUNCT
bjp-62725	7	43	2022	2022	NUM
bjp-62725	7	44	)	)	PUNCT
bjp-62725	7	45	.	.	PUNCT
bjp-62725	8	1	the	the	DET
bjp-62725	8	2	breakdown	breakdown	NOUN
bjp-62725	8	3	of	of	ADP
bjp-62725	8	4	chondrocytes	chondrocyte	NOUN
bjp-62725	8	5	is	be	AUX
bjp-62725	8	6	attributed	attribute	VERB
bjp-62725	8	7	to	to	ADP
bjp-62725	8	8	dedifferentiation	dedifferentiation	NOUN
bjp-62725	8	9	,	,	PUNCT
bjp-62725	8	10	an	an	DET
bjp-62725	8	11	imbalance	imbalance	NOUN
bjp-62725	8	12	between	between	ADP
bjp-62725	8	13	matrix	matrix	NOUN
bjp-62725	8	14	metalloproteases	metalloprotease	NOUN
bjp-62725	8	15	and	and	CCONJ
bjp-62725	8	16	their	their	PRON
bjp-62725	8	17	inhibitors	inhibitor	NOUN
bjp-62725	8	18	,	,	PUNCT
bjp-62725	8	19	apoptosis	apoptosis	NOUN
bjp-62725	8	20	,	,	PUNCT
bjp-62725	8	21	the	the	DET
bjp-62725	8	22	release	release	NOUN
bjp-62725	8	23	of	of	ADP
bjp-62725	8	24	pro	pro	ADJ
bjp-62725	8	25	-	-	ADJ
bjp-62725	8	26	inflammatory	inflammatory	ADJ
bjp-62725	8	27	cytokines	cytokine	NOUN
bjp-62725	8	28	,	,	PUNCT
bjp-62725	8	29	retinoic	retinoic	ADJ
bjp-62725	8	30	acid	acid	NOUN
bjp-62725	8	31	,	,	PUNCT
bjp-62725	8	32	and	and	CCONJ
bjp-62725	8	33	monolayer	monolayer	NOUN
bjp-62725	8	34	culture	culture	NOUN
bjp-62725	8	35	(	(	PUNCT
bjp-62725	8	36	yu	yu	PROPN
bjp-62725	8	37	and	and	CCONJ
bjp-62725	8	38	kim	kim	PROPN
bjp-62725	8	39	,	,	PUNCT
bjp-62725	8	40	2011	2011	NUM
bjp-62725	8	41	;	;	PUNCT
bjp-62725	8	42	charlier	charlier	PROPN
bjp-62725	8	43	et	et	PROPN
bjp-62725	8	44	al	al	PROPN
bjp-62725	8	45	.	.	PROPN
bjp-62725	8	46	,	,	PUNCT
bjp-62725	8	47	2019	2019	NUM
bjp-62725	8	48	;	;	PUNCT
bjp-62725	9	1	ghosh	ghosh	PROPN
bjp-62725	9	2	et	et	PROPN
bjp-62725	9	3	al	al	PROPN
bjp-62725	9	4	.	.	PROPN
bjp-62725	9	5	,	,	PUNCT
bjp-62725	9	6	2022	2022	NUM
bjp-62725	9	7	)	)	PUNCT
bjp-62725	9	8	.	.	PUNCT
bjp-62725	10	1	it	it	PRON
bjp-62725	10	2	has	have	AUX
bjp-62725	10	3	been	be	AUX
bjp-62725	10	4	reported	report	VERB
bjp-62725	10	5	that	that	SCONJ
bjp-62725	10	6	the	the	DET
bjp-62725	10	7	structure	structure	NOUN
bjp-62725	10	8	of	of	ADP
bjp-62725	10	9	the	the	DET
bjp-62725	10	10	cytoskeleton	cytoskeleton	NOUN
bjp-62725	10	11	acts	act	VERB
bjp-62725	10	12	as	as	ADP
bjp-62725	10	13	an	an	DET
bjp-62725	10	14	important	important	ADJ
bjp-62725	10	15	factor	factor	NOUN
bjp-62725	10	16	in	in	ADP
bjp-62725	10	17	determining	determine	VERB
bjp-62725	10	18	the	the	DET
bjp-62725	10	19	abstract	abstract	ADJ
bjp-62725	10	20	the	the	DET
bjp-62725	10	21	role	role	NOUN
bjp-62725	10	22	of	of	ADP
bjp-62725	10	23	cell	cell	NOUN
bjp-62725	10	24	morphological	morphological	ADJ
bjp-62725	10	25	changes	change	NOUN
bjp-62725	10	26	in	in	ADP
bjp-62725	10	27	colchicine	colchicine	NOUN
bjp-62725	10	28	-	-	PUNCT
bjp-62725	10	29	inhibited	inhibit	VERB
bjp-62725	10	30	tubulin	tubulin	NOUN
bjp-62725	10	31	polymerization	polymerization	NOUN
bjp-62725	10	32	of	of	ADP
bjp-62725	10	33	rabbit	rabbit	NOUN
bjp-62725	10	34	articular	articular	ADJ
bjp-62725	10	35	chondrocytes	chondrocyte	NOUN
bjp-62725	10	36	and	and	CCONJ
bjp-62725	10	37	their	their	PRON
bjp-62725	10	38	involvement	involvement	NOUN
bjp-62725	10	39	in	in	ADP
bjp-62725	10	40	dedifferentiation	dedifferentiation	NOUN
bjp-62725	10	41	were	be	AUX
bjp-62725	10	42	investigated	investigate	VERB
bjp-62725	10	43	.	.	PUNCT
bjp-62725	11	1	colchicine	colchicine	PROPN
bjp-62725	11	2	treatment	treatment	PROPN
bjp-62725	11	3	resulted	result	VERB
bjp-62725	11	4	in	in	ADP
bjp-62725	11	5	the	the	DET
bjp-62725	11	6	dedifferentiation	dedifferentiation	NOUN
bjp-62725	11	7	of	of	ADP
bjp-62725	11	8	chondrocytes	chondrocyte	NOUN
bjp-62725	11	9	,	,	PUNCT
bjp-62725	11	10	which	which	PRON
bjp-62725	11	11	was	be	AUX
bjp-62725	11	12	supported	support	VERB
bjp-62725	11	13	by	by	ADP
bjp-62725	11	14	the	the	DET
bjp-62725	11	15	loss	loss	NOUN
bjp-62725	11	16	of	of	ADP
bjp-62725	11	17	type	type	NOUN
bjp-62725	11	18	ii	ii	NOUN
bjp-62725	11	19	collagen	collagen	NOUN
bjp-62725	11	20	expression	expression	NOUN
bjp-62725	11	21	and	and	CCONJ
bjp-62725	11	22	proteoglycan	proteoglycan	ADJ
bjp-62725	11	23	production	production	NOUN
bjp-62725	11	24	.	.	PUNCT
bjp-62725	12	1	inhibition	inhibition	NOUN
bjp-62725	12	2	of	of	ADP
bjp-62725	12	3	tubulin	tubulin	NOUN
bjp-62725	12	4	depolymerization	depolymerization	NOUN
bjp-62725	12	5	with	with	ADP
bjp-62725	12	6	paclitaxel	paclitaxel	PROPN
bjp-62725	12	7	rescued	rescue	VERB
bjp-62725	12	8	colchicine	colchicine	PROPN
bjp-62725	12	9	-	-	PUNCT
bjp-62725	12	10	caused	cause	VERB
bjp-62725	12	11	dedifferentiation	dedifferentiation	NOUN
bjp-62725	12	12	and	and	CCONJ
bjp-62725	12	13	tubulin	tubulin	NOUN
bjp-62725	12	14	polymerization	polymerization	NOUN
bjp-62725	12	15	.	.	PUNCT
bjp-62725	13	1	additionally	additionally	ADV
bjp-62725	13	2	,	,	PUNCT
bjp-62725	13	3	colchicine	colchicine	PROPN
bjp-62725	13	4	stimulated	stimulate	VERB
bjp-62725	13	5	β	β	NOUN
bjp-62725	13	6	-	-	ADJ
bjp-62725	13	7	catenin	catenin	ADJ
bjp-62725	13	8	overexpression	overexpression	NOUN
bjp-62725	13	9	,	,	PUNCT
bjp-62725	13	10	which	which	PRON
bjp-62725	13	11	is	be	AUX
bjp-62725	13	12	characterized	characterize	VERB
bjp-62725	13	13	by	by	ADP
bjp-62725	13	14	the	the	DET
bjp-62725	13	15	accumulation	accumulation	NOUN
bjp-62725	13	16	of	of	ADP
bjp-62725	13	17	β	β	NOUN
bjp-62725	13	18	-	-	NOUN
bjp-62725	13	19	catenin	catenin	NOUN
bjp-62725	13	20	into	into	ADP
bjp-62725	13	21	the	the	DET
bjp-62725	13	22	cytosol	cytosol	NOUN
bjp-62725	13	23	determined	determine	VERB
bjp-62725	13	24	by	by	ADP
bjp-62725	13	25	immunofluorescence	immunofluorescence	NOUN
bjp-62725	13	26	staining	stain	VERB
bjp-62725	13	27	.	.	PUNCT
bjp-62725	14	1	inhibition	inhibition	NOUN
bjp-62725	14	2	of	of	ADP
bjp-62725	14	3	the	the	DET
bjp-62725	14	4	βcatenin	βcatenin	ADJ
bjp-62725	14	5	-	-	PUNCT
bjp-62725	14	6	mediated	mediate	VERB
bjp-62725	14	7	pathway	pathway	NOUN
bjp-62725	14	8	by	by	ADP
bjp-62725	14	9	sir	sir	PROPN
bjp-62725	14	10	β	β	PROPN
bjp-62725	14	11	-	-	ADJ
bjp-62725	14	12	catenin	catenin	ADJ
bjp-62725	14	13	recovered	recover	VERB
bjp-62725	14	14	colchicine	colchicine	NOUN
bjp-62725	14	15	-	-	PUNCT
bjp-62725	14	16	caused	cause	VERB
bjp-62725	14	17	the	the	DET
bjp-62725	14	18	suppression	suppression	NOUN
bjp-62725	14	19	of	of	ADP
bjp-62725	14	20	type	type	NOUN
bjp-62725	14	21	ii	ii	NOUN
bjp-62725	14	22	collagen	collagen	NOUN
bjp-62725	14	23	expression	expression	NOUN
bjp-62725	14	24	in	in	ADP
bjp-62725	14	25	the	the	DET
bjp-62725	14	26	chondrocytes	chondrocyte	NOUN
bjp-62725	14	27	.	.	PUNCT
bjp-62725	15	1	treatment	treatment	NOUN
bjp-62725	15	2	with	with	ADP
bjp-62725	15	3	colchicine	colchicine	PROPN
bjp-62725	15	4	also	also	ADV
bjp-62725	15	5	induced	induce	VERB
bjp-62725	15	6	inflammation	inflammation	NOUN
bjp-62725	15	7	,	,	PUNCT
bjp-62725	15	8	as	as	SCONJ
bjp-62725	15	9	determined	determine	VERB
bjp-62725	15	10	by	by	ADP
bjp-62725	15	11	the	the	DET
bjp-62725	15	12	increased	increase	VERB
bjp-62725	15	13	expression	expression	NOUN
bjp-62725	15	14	level	level	NOUN
bjp-62725	15	15	of	of	ADP
bjp-62725	15	16	cyclooxygenase-2	cyclooxygenase-2	NUM
bjp-62725	15	17	and	and	CCONJ
bjp-62725	15	18	decreased	decrease	VERB
bjp-62725	15	19	iκb	iκb	PROPN
bjp-62725	15	20	-	-	PUNCT
bjp-62725	15	21	α	α	NOUN
bjp-62725	15	22	expression	expression	NOUN
bjp-62725	15	23	level	level	NOUN
bjp-62725	15	24	by	by	ADP
bjp-62725	15	25	western	western	ADJ
bjp-62725	15	26	blot	blot	NOUN
bjp-62725	15	27	analysis	analysis	NOUN
bjp-62725	15	28	.	.	PUNCT
bjp-62725	16	1	modulating	modulate	VERB
bjp-62725	16	2	the	the	DET
bjp-62725	16	3	expression	expression	NOUN
bjp-62725	16	4	levels	level	NOUN
bjp-62725	16	5	of	of	ADP
bjp-62725	16	6	piκbα	piκbα	NOUN
bjp-62725	16	7	and	and	CCONJ
bjp-62725	16	8	iκbα	iκbα	ADV
bjp-62725	16	9	via	via	ADP
bjp-62725	16	10	bms	bms	PROPN
bjp-62725	16	11	345541	345541	NUM
bjp-62725	16	12	,	,	PUNCT
bjp-62725	16	13	was	be	AUX
bjp-62725	16	14	able	able	ADJ
bjp-62725	16	15	to	to	PART
bjp-62725	16	16	modulate	modulate	VERB
bjp-62725	16	17	colchicine	colchicine	NOUN
bjp-62725	16	18	-	-	PUNCT
bjp-62725	16	19	induced	induce	VERB
bjp-62725	16	20	inflammatory	inflammatory	ADJ
bjp-62725	16	21	effect	effect	NOUN
bjp-62725	16	22	.	.	PUNCT
bjp-62725	17	1	article	article	NOUN
bjp-62725	17	2	info	info	NOUN
bjp-62725	17	3	received	receive	VERB
bjp-62725	17	4	:	:	PUNCT
bjp-62725	17	5	7	7	NUM
bjp-62725	17	6	november	november	PROPN
bjp-62725	17	7	2022	2022	NUM
bjp-62725	17	8	accepted	accept	VERB
bjp-62725	17	9	:	:	PUNCT
bjp-62725	17	10	28	28	NUM
bjp-62725	17	11	december	december	PROPN
bjp-62725	17	12	2022	2022	NUM
bjp-62725	17	13	available	available	ADJ
bjp-62725	17	14	online	online	ADV
bjp-62725	17	15	:	:	PUNCT
bjp-62725	17	16	13	13	NUM
bjp-62725	17	17	january	january	PROPN
bjp-62725	17	18	2023	2023	NUM
bjp-62725	17	19	doi	doi	NOUN
bjp-62725	17	20	:	:	PUNCT
bjp-62725	17	21	10.3329	10.3329	NUM
bjp-62725	17	22	/	/	SYM
bjp-62725	17	23	bjp.v18i1.62725	bjp.v18i1.62725	PROPN
bjp-62725	17	24	cite	cite	VERB
bjp-62725	17	25	this	this	DET
bjp-62725	17	26	article	article	NOUN
bjp-62725	17	27	:	:	PUNCT
bjp-62725	17	28	han	han	PROPN
bjp-62725	17	29	y	y	PROPN
bjp-62725	17	30	,	,	PUNCT
bjp-62725	17	31	eom	eom	PROPN
bjp-62725	17	32	ys	ys	NOUN
bjp-62725	17	33	,	,	PUNCT
bjp-62725	17	34	shah	shah	PROPN
bjp-62725	17	35	fh	fh	PROPN
bjp-62725	17	36	,	,	PUNCT
bjp-62725	17	37	kim	kim	PROPN
bjp-62725	17	38	sj	sj	PROPN
bjp-62725	17	39	.	.	PUNCT
bjp-62725	17	40	destabilising	destabilising	ADJ
bjp-62725	17	41	microtubule	microtubule	NOUN
bjp-62725	17	42	polymerization	polymerization	NOUN
bjp-62725	17	43	regulates	regulate	VERB
bjp-62725	17	44	chondrocyte	chondrocyte	PROPN
bjp-62725	17	45	dedifferentiation	dedifferentiation	NOUN
bjp-62725	17	46	and	and	CCONJ
bjp-62725	17	47	inflammation	inflammation	NOUN
bjp-62725	17	48	via	via	ADP
bjp-62725	17	49	nuclear	nuclear	ADJ
bjp-62725	17	50	factor	factor	NOUN
bjp-62725	17	51	kappa	kappa	PROPN
bjp-62725	17	52	b	b	PROPN
bjp-62725	17	53	and	and	CCONJ
bjp-62725	17	54	β	β	NOUN
bjp-62725	17	55	-	-	ADJ
bjp-62725	17	56	catenin	catenin	ADJ
bjp-62725	17	57	pathway	pathway	NOUN
bjp-62725	17	58	.	.	PUNCT
bjp-62725	18	1	bangladesh	bangladesh	PROPN
bjp-62725	18	2	j	j	PROPN
bjp-62725	18	3	pharmacol	pharmacol	PROPN
bjp-62725	18	4	.	.	PUNCT
bjp-62725	19	1	2023	2023	NUM
bjp-62725	19	2	;	;	PUNCT
bjp-62725	19	3	18	18	NUM
bjp-62725	19	4	:	:	SYM
bjp-62725	19	5	8	8	NUM
bjp-62725	19	6	-	-	SYM
bjp-62725	19	7	16	16	NUM
bjp-62725	19	8	.	.	PUNCT
bjp-62725	20	1	destabilising	destabilise	VERB
bjp-62725	20	2	microtubule	microtubule	NOUN
bjp-62725	20	3	polymerization	polymerization	NOUN
bjp-62725	20	4	regulates	regulate	VERB
bjp-62725	20	5	chondrocyte	chondrocyte	PROPN
bjp-62725	20	6	dedifferentiation	dedifferentiation	NOUN
bjp-62725	20	7	and	and	CCONJ
bjp-62725	20	8	inflammation	inflammation	NOUN
bjp-62725	20	9	via	via	ADP
bjp-62725	20	10	nuclear	nuclear	ADJ
bjp-62725	20	11	factor	factor	NOUN
bjp-62725	20	12	kappa	kappa	PROPN
bjp-62725	20	13	b	b	PROPN
bjp-62725	20	14	and	and	CCONJ
bjp-62725	20	15	β	β	X
bjp-62725	20	16	-catenin	-catenin	ADJ
bjp-62725	20	17	pathway	pathway	NOUN
bjp-62725	20	18	yohan	yohan	PROPN
bjp-62725	20	19	han	han	PROPN
bjp-62725	20	20	,	,	PUNCT
bjp-62725	20	21	young	young	ADJ
bjp-62725	20	22	seok	seok	PROPN
bjp-62725	20	23	eom	eom	PROPN
bjp-62725	20	24	,	,	PUNCT
bjp-62725	20	25	fahad	fahad	VERB
bjp-62725	20	26	hassan	hassan	PROPN
bjp-62725	20	27	shah	shah	PROPN
bjp-62725	20	28	and	and	CCONJ
bjp-62725	20	29	song	song	NOUN
bjp-62725	20	30	ja	ja	PROPN
bjp-62725	20	31	kim	kim	PROPN
bjp-62725	20	32	department	department	PROPN
bjp-62725	20	33	of	of	ADP
bjp-62725	20	34	biological	biological	ADJ
bjp-62725	20	35	sciences	science	NOUN
bjp-62725	20	36	,	,	PUNCT
bjp-62725	20	37	college	college	NOUN
bjp-62725	20	38	of	of	ADP
bjp-62725	20	39	natural	natural	ADJ
bjp-62725	20	40	sciences	science	NOUN
bjp-62725	20	41	,	,	PUNCT
bjp-62725	20	42	kongju	kongju	PROPN
bjp-62725	20	43	national	national	PROPN
bjp-62725	20	44	university	university	PROPN
bjp-62725	20	45	,	,	PUNCT
bjp-62725	20	46	gongju	gongju	PROPN
bjp-62725	20	47	32588	32588	NUM
bjp-62725	20	48	,	,	PUNCT
bjp-62725	20	49	republic	republic	NOUN
bjp-62725	20	50	of	of	ADP
bjp-62725	20	51	korea	korea	PROPN
bjp-62725	20	52	.	.	PUNCT
bjp-62725	21	1	this	this	DET
bjp-62725	21	2	work	work	NOUN
bjp-62725	21	3	is	be	AUX
bjp-62725	21	4	licensed	license	VERB
bjp-62725	21	5	under	under	ADP
bjp-62725	21	6	a	a	DET
bjp-62725	21	7	creative	creative	ADJ
bjp-62725	21	8	commons	common	NOUN
bjp-62725	21	9	attribution	attribution	NOUN
bjp-62725	21	10	4.0	4.0	NUM
bjp-62725	21	11	license	license	NOUN
bjp-62725	21	12	.	.	PUNCT
bjp-62725	22	1	you	you	PRON
bjp-62725	22	2	are	be	AUX
bjp-62725	22	3	free	free	ADJ
bjp-62725	22	4	to	to	PART
bjp-62725	22	5	copy	copy	VERB
bjp-62725	22	6	,	,	PUNCT
bjp-62725	22	7	distribute	distribute	VERB
bjp-62725	22	8	and	and	CCONJ
bjp-62725	22	9	perform	perform	VERB
bjp-62725	22	10	the	the	DET
bjp-62725	22	11	work	work	NOUN
bjp-62725	22	12	.	.	PUNCT
bjp-62725	23	1	you	you	PRON
bjp-62725	23	2	must	must	AUX
bjp-62725	23	3	attribute	attribute	VERB
bjp-62725	23	4	the	the	DET
bjp-62725	23	5	work	work	NOUN
bjp-62725	23	6	in	in	ADP
bjp-62725	23	7	the	the	DET
bjp-62725	23	8	manner	manner	NOUN
bjp-62725	23	9	specified	specify	VERB
bjp-62725	23	10	by	by	ADP
bjp-62725	23	11	the	the	DET
bjp-62725	23	12	author	author	NOUN
bjp-62725	23	13	or	or	CCONJ
bjp-62725	23	14	licensor	licensor	NOUN
bjp-62725	23	15	.	.	PUNCT
bjp-62725	24	1	a	a	DET
bjp-62725	24	2	journal	journal	NOUN
bjp-62725	24	3	of	of	ADP
bjp-62725	24	4	the	the	DET
bjp-62725	24	5	bangladesh	bangladesh	NOUN
bjp-62725	24	6	pharmacological	pharmacological	ADJ
bjp-62725	24	7	society	society	NOUN
bjp-62725	24	8	(	(	PUNCT
bjp-62725	24	9	bdps	bdps	NOUN
bjp-62725	24	10	)	)	PUNCT
bjp-62725	24	11	bangladesh	bangladesh	PROPN
bjp-62725	24	12	j	j	PROPN
bjp-62725	24	13	pharmacol	pharmacol	PROPN
bjp-62725	24	14	2023	2023	NUM
bjp-62725	24	15	;	;	PUNCT
bjp-62725	24	16	18	18	NUM
bjp-62725	24	17	:	:	SYM
bjp-62725	24	18	8	8	NUM
bjp-62725	24	19	-	-	SYM
bjp-62725	24	20	16	16	NUM
bjp-62725	24	21	journal	journal	NOUN
bjp-62725	24	22	homepage	homepage	NOUN
bjp-62725	24	23	:	:	PUNCT
bjp-62725	24	24	www.banglajol.info	www.banglajol.info	PROPN
bjp-62725	24	25	;	;	PUNCT
bjp-62725	24	26	www.bdpsjournal.org	www.bdpsjournal.org	NUM
bjp-62725	24	27	abstracted	abstract	VERB
bjp-62725	24	28	/	/	SYM
bjp-62725	24	29	indexed	index	VERB
bjp-62725	24	30	in	in	ADP
bjp-62725	24	31	academic	academic	ADJ
bjp-62725	24	32	search	search	NOUN
bjp-62725	24	33	complete	complete	ADJ
bjp-62725	24	34	,	,	PUNCT
bjp-62725	24	35	agroforestry	agroforestry	NOUN
bjp-62725	24	36	abstracts	abstract	NOUN
bjp-62725	24	37	,	,	PUNCT
bjp-62725	24	38	asia	asia	PROPN
bjp-62725	24	39	journals	journal	NOUN
bjp-62725	24	40	online	online	ADV
bjp-62725	24	41	,	,	PUNCT
bjp-62725	24	42	bangladesh	bangladesh	NOUN
bjp-62725	24	43	journals	journal	NOUN
bjp-62725	24	44	online	online	ADV
bjp-62725	24	45	,	,	PUNCT
bjp-62725	24	46	biological	biological	ADJ
bjp-62725	24	47	abstracts	abstract	NOUN
bjp-62725	24	48	,	,	PUNCT
bjp-62725	24	49	biosis	biosis	NOUN
bjp-62725	24	50	previews	preview	NOUN
bjp-62725	24	51	,	,	PUNCT
bjp-62725	24	52	cab	cab	NOUN
bjp-62725	24	53	abstracts	abstract	NOUN
bjp-62725	24	54	,	,	PUNCT
bjp-62725	24	55	current	current	ADJ
bjp-62725	24	56	abstracts	abstract	NOUN
bjp-62725	24	57	,	,	PUNCT
bjp-62725	24	58	directory	directory	NOUN
bjp-62725	24	59	of	of	ADP
bjp-62725	24	60	open	open	ADJ
bjp-62725	24	61	access	access	NOUN
bjp-62725	24	62	journals	journal	NOUN
bjp-62725	24	63	,	,	PUNCT
bjp-62725	24	64	embase	embase	NOUN
bjp-62725	24	65	/	/	SYM
bjp-62725	24	66	excerpta	excerpta	NOUN
bjp-62725	24	67	medica	medica	NOUN
bjp-62725	24	68	,	,	PUNCT
bjp-62725	24	69	global	global	ADJ
bjp-62725	24	70	health	health	NOUN
bjp-62725	24	71	,	,	PUNCT
bjp-62725	24	72	google	google	PROPN
bjp-62725	24	73	scholar	scholar	NOUN
bjp-62725	24	74	,	,	PUNCT
bjp-62725	24	75	hinari	hinari	X
bjp-62725	24	76	(	(	PUNCT
bjp-62725	24	77	who	who	PRON
bjp-62725	24	78	)	)	PUNCT
bjp-62725	24	79	,	,	PUNCT
bjp-62725	24	80	international	international	ADJ
bjp-62725	24	81	pharmaceutical	pharmaceutical	ADJ
bjp-62725	24	82	abstracts	abstract	NOUN
bjp-62725	24	83	,	,	PUNCT
bjp-62725	24	84	open	open	ADJ
bjp-62725	24	85	j	j	PROPN
bjp-62725	24	86	-	-	PUNCT
bjp-62725	24	87	gate	gate	NOUN
bjp-62725	24	88	,	,	PUNCT
bjp-62725	24	89	science	science	NOUN
bjp-62725	24	90	citation	citation	NOUN
bjp-62725	24	91	index	index	NOUN
bjp-62725	24	92	expanded	expand	VERB
bjp-62725	24	93	,	,	PUNCT
bjp-62725	24	94	scopus	scopus	NOUN
bjp-62725	24	95	and	and	CCONJ
bjp-62725	24	96	social	social	ADJ
bjp-62725	24	97	sciences	sciences	PROPN
bjp-62725	24	98	citation	citation	NOUN
bjp-62725	24	99	index	index	NOUN
bjp-62725	24	100	issn	issn	PROPN
bjp-62725	24	101	:	:	PUNCT
bjp-62725	24	102	1991	1991	NUM
bjp-62725	24	103	-	-	SYM
bjp-62725	24	104	0088	0088	NUM
bjp-62725	24	105	phenotype	phenotype	NOUN
bjp-62725	24	106	of	of	ADP
bjp-62725	24	107	chondrocytes	chondrocyte	NOUN
bjp-62725	24	108	(	(	PUNCT
bjp-62725	24	109	kim	kim	PROPN
bjp-62725	24	110	et	et	PROPN
bjp-62725	24	111	al	al	PROPN
bjp-62725	24	112	.	.	PROPN
bjp-62725	24	113	,	,	PUNCT
bjp-62725	24	114	2012	2012	NUM
bjp-62725	24	115	;	;	PUNCT
bjp-62725	24	116	han	han	PROPN
bjp-62725	24	117	and	and	CCONJ
bjp-62725	24	118	kim	kim	PROPN
bjp-62725	24	119	,	,	PUNCT
bjp-62725	24	120	2018	2018	NUM
bjp-62725	24	121	)	)	PUNCT
bjp-62725	24	122	.	.	PUNCT
bjp-62725	25	1	actin	actin	PROPN
bjp-62725	25	2	cytoskeleton	cytoskeleton	PROPN
bjp-62725	25	3	alterations	alteration	NOUN
bjp-62725	25	4	can	can	AUX
bjp-62725	25	5	be	be	AUX
bjp-62725	25	6	seen	see	VERB
bjp-62725	25	7	in	in	ADP
bjp-62725	25	8	chondrocytes	chondrocyte	NOUN
bjp-62725	25	9	dedifferentiated	dedifferentiate	VERB
bjp-62725	25	10	by	by	ADP
bjp-62725	25	11	retinoic	retinoic	PROPN
bjp-62725	25	12	acid	acid	PROPN
bjp-62725	25	13	or	or	CCONJ
bjp-62725	25	14	monolayer	monolayer	NOUN
bjp-62725	25	15	cultures	culture	NOUN
bjp-62725	25	16	(	(	PUNCT
bjp-62725	25	17	yu	yu	PROPN
bjp-62725	25	18	and	and	CCONJ
bjp-62725	25	19	kim	kim	PROPN
bjp-62725	25	20	,	,	PUNCT
bjp-62725	25	21	2011	2011	NUM
bjp-62725	25	22	;	;	PUNCT
bjp-62725	25	23	charlier	charlier	PROPN
bjp-62725	25	24	et	et	PROPN
bjp-62725	25	25	al	al	PROPN
bjp-62725	25	26	.	.	PROPN
bjp-62725	25	27	,	,	PUNCT
bjp-62725	25	28	2019	2019	NUM
bjp-62725	25	29	)	)	PUNCT
bjp-62725	25	30	.	.	PUNCT
bjp-62725	26	1	disruption	disruption	NOUN
bjp-62725	26	2	of	of	ADP
bjp-62725	26	3	the	the	DET
bjp-62725	26	4	actin	actin	NOUN
bjp-62725	26	5	cytoskeleton	cytoskeleton	PROPN
bjp-62725	26	6	by	by	ADP
bjp-62725	26	7	cytochalasin	cytochalasin	PROPN
bjp-62725	26	8	d	d	NOUN
bjp-62725	26	9	or	or	CCONJ
bjp-62725	26	10	simvastatin	simvastatin	PROPN
bjp-62725	26	11	causes	cause	VERB
bjp-62725	26	12	redifferentiation	redifferentiation	NOUN
bjp-62725	26	13	from	from	ADP
bjp-62725	26	14	dedifferentiated	dedifferentiated	ADJ
bjp-62725	26	15	chondrocytes	chondrocyte	NOUN
bjp-62725	26	16	(	(	PUNCT
bjp-62725	26	17	kim	kim	PROPN
bjp-62725	26	18	et	et	PROPN
bjp-62725	26	19	al	al	PROPN
bjp-62725	26	20	.	.	PROPN
bjp-62725	26	21	,	,	PUNCT
bjp-62725	26	22	2012	2012	NUM
bjp-62725	26	23	;	;	PUNCT
bjp-62725	26	24	beier	beier	X
bjp-62725	26	25	,	,	PUNCT
bjp-62725	26	26	2016	2016	NUM
bjp-62725	26	27	;	;	PUNCT
bjp-62725	26	28	han	han	PROPN
bjp-62725	26	29	and	and	CCONJ
bjp-62725	26	30	kim	kim	PROPN
bjp-62725	26	31	,	,	PUNCT
bjp-62725	26	32	2018	2018	NUM
bjp-62725	26	33	)	)	PUNCT
bjp-62725	26	34	.	.	PUNCT
bjp-62725	27	1	microtubules	microtubule	NOUN
bjp-62725	27	2	are	be	AUX
bjp-62725	27	3	essential	essential	ADJ
bjp-62725	27	4	structural	structural	ADJ
bjp-62725	27	5	components	component	NOUN
bjp-62725	27	6	for	for	ADP
bjp-62725	27	7	maintaining	maintain	VERB
bjp-62725	27	8	cell	cell	NOUN
bjp-62725	27	9	skeleton	skeleton	NOUN
bjp-62725	27	10	and	and	CCONJ
bjp-62725	27	11	morphology	morphology	NOUN
bjp-62725	27	12	in	in	ADP
bjp-62725	27	13	tumor	tumor	NOUN
bjp-62725	27	14	cells	cell	NOUN
bjp-62725	27	15	as	as	ADV
bjp-62725	27	16	well	well	ADV
bjp-62725	27	17	as	as	ADP
bjp-62725	27	18	normal	normal	ADJ
bjp-62725	27	19	cells	cell	NOUN
bjp-62725	27	20	(	(	PUNCT
bjp-62725	27	21	goodson	goodson	NOUN
bjp-62725	27	22	and	and	CCONJ
bjp-62725	27	23	jonasson	jonasson	PROPN
bjp-62725	27	24	,	,	PUNCT
bjp-62725	27	25	2018	2018	NUM
bjp-62725	27	26	)	)	PUNCT
bjp-62725	27	27	.	.	PUNCT
bjp-62725	28	1	they	they	PRON
bjp-62725	28	2	also	also	ADV
bjp-62725	28	3	perform	perform	VERB
bjp-62725	28	4	various	various	ADJ
bjp-62725	28	5	functions	function	NOUN
bjp-62725	28	6	such	such	ADJ
bjp-62725	28	7	as	as	ADP
bjp-62725	28	8	organelle	organelle	NOUN
bjp-62725	28	9	-	-	PUNCT
bjp-62725	28	10	cell	cell	NOUN
bjp-62725	28	11	migration	migration	NOUN
bjp-62725	28	12	and	and	CCONJ
bjp-62725	28	13	micromolecular	micromolecular	ADJ
bjp-62725	28	14	transport	transport	NOUN
bjp-62725	28	15	.	.	PUNCT
bjp-62725	29	1	β	β	X
bjp-62725	29	2	-	-	PUNCT
bjp-62725	29	3	catenin	catenin	NOUN
bjp-62725	29	4	is	be	AUX
bjp-62725	29	5	a	a	DET
bjp-62725	29	6	versatile	versatile	ADJ
bjp-62725	29	7	transcription	transcription	NOUN
bjp-62725	29	8	factor	factor	NOUN
bjp-62725	29	9	and	and	CCONJ
bjp-62725	29	10	a	a	DET
bjp-62725	29	11	crucial	crucial	ADJ
bjp-62725	29	12	structural	structural	ADJ
bjp-62725	29	13	element	element	NOUN
bjp-62725	29	14	of	of	ADP
bjp-62725	29	15	cadherin	cadherin	NOUN
bjp-62725	29	16	-	-	PUNCT
bjp-62725	29	17	based	base	VERB
bjp-62725	29	18	adhesion	adhesion	NOUN
bjp-62725	29	19	junctions	junction	NOUN
bjp-62725	29	20	.	.	PUNCT
bjp-62725	30	1	it	it	PRON
bjp-62725	30	2	is	be	AUX
bjp-62725	30	3	a	a	DET
bjp-62725	30	4	key	key	ADJ
bjp-62725	30	5	regulator	regulator	NOUN
bjp-62725	30	6	of	of	ADP
bjp-62725	30	7	the	the	DET
bjp-62725	30	8	conventional	conventional	ADJ
bjp-62725	30	9	wnt	wnt	NOUN
bjp-62725	30	10	signaling	signal	VERB
bjp-62725	30	11	pathway	pathway	NOUN
bjp-62725	30	12	.	.	PUNCT
bjp-62725	31	1	the	the	DET
bjp-62725	31	2	wnt/	wnt/	NOUN
bjp-62725	31	3	β	β	NOUN
bjp-62725	31	4	-	-	ADJ
bjp-62725	31	5	catenin	catenin	ADJ
bjp-62725	31	6	signaling	signal	VERB
bjp-62725	31	7	pathway	pathway	NOUN
bjp-62725	31	8	is	be	AUX
bjp-62725	31	9	crucial	crucial	ADJ
bjp-62725	31	10	for	for	ADP
bjp-62725	31	11	cell	cell	NOUN
bjp-62725	31	12	differentiation	differentiation	NOUN
bjp-62725	31	13	,	,	PUNCT
bjp-62725	31	14	growth	growth	NOUN
bjp-62725	31	15	,	,	PUNCT
bjp-62725	31	16	proliferation	proliferation	NOUN
bjp-62725	31	17	,	,	PUNCT
bjp-62725	31	18	and	and	CCONJ
bjp-62725	31	19	the	the	DET
bjp-62725	31	20	development	development	NOUN
bjp-62725	31	21	of	of	ADP
bjp-62725	31	22	cancer	cancer	NOUN
bjp-62725	31	23	(	(	PUNCT
bjp-62725	31	24	zhang	zhang	PROPN
bjp-62725	31	25	et	et	PROPN
bjp-62725	31	26	al	al	PROPN
bjp-62725	31	27	.	.	PROPN
bjp-62725	31	28	,	,	PUNCT
bjp-62725	31	29	2020	2020	NUM
bjp-62725	31	30	)	)	PUNCT
bjp-62725	31	31	.	.	PUNCT
bjp-62725	32	1	in	in	ADP
bjp-62725	32	2	the	the	DET
bjp-62725	32	3	absence	absence	NOUN
bjp-62725	32	4	of	of	ADP
bjp-62725	32	5	wnt	wnt	PROPN
bjp-62725	32	6	ligand	ligand	PROPN
bjp-62725	32	7	protein	protein	NOUN
bjp-62725	32	8	,	,	PUNCT
bjp-62725	32	9	β	β	X
bjp-62725	32	10	-	-	NOUN
bjp-62725	32	11	catenin	catenin	NOUN
bjp-62725	32	12	is	be	AUX
bjp-62725	32	13	phosphorylated	phosphorylate	VERB
bjp-62725	32	14	by	by	ADP
bjp-62725	32	15	the	the	DET
bjp-62725	32	16	gsk3	gsk3	PROPN
bjp-62725	32	17	complex	complex	NOUN
bjp-62725	32	18	(	(	PUNCT
bjp-62725	32	19	huang	huang	PROPN
bjp-62725	32	20	et	et	PROPN
bjp-62725	32	21	al	al	PROPN
bjp-62725	32	22	.	.	PROPN
bjp-62725	32	23	,	,	PUNCT
bjp-62725	32	24	2019	2019	NUM
bjp-62725	32	25	)	)	PUNCT
bjp-62725	32	26	.	.	PUNCT
bjp-62725	33	1	phosphorylated	phosphorylate	VERB
bjp-62725	33	2	β	β	NOUN
bjp-62725	33	3	-	-	NOUN
bjp-62725	33	4	catenin	catenin	NOUN
bjp-62725	33	5	,	,	PUNCT
bjp-62725	33	6	which	which	PRON
bjp-62725	33	7	is	be	AUX
bjp-62725	33	8	marked	mark	VERB
bjp-62725	33	9	with	with	ADP
bjp-62725	33	10	ubiquitin	ubiquitin	NOUN
bjp-62725	33	11	is	be	AUX
bjp-62725	33	12	recognized	recognize	VERB
bjp-62725	33	13	and	and	CCONJ
bjp-62725	33	14	degraded	degrade	VERB
bjp-62725	33	15	by	by	ADP
bjp-62725	33	16	the	the	DET
bjp-62725	33	17	proteasome	proteasome	NOUN
bjp-62725	33	18	.	.	PUNCT
bjp-62725	34	1	conversely	conversely	ADV
bjp-62725	34	2	,	,	PUNCT
bjp-62725	34	3	the	the	DET
bjp-62725	34	4	presence	presence	NOUN
bjp-62725	34	5	of	of	ADP
bjp-62725	34	6	wnt	wnt	PROPN
bjp-62725	34	7	ligand	ligand	PROPN
bjp-62725	34	8	inhibits	inhibit	VERB
bjp-62725	34	9	the	the	DET
bjp-62725	34	10	degradation	degradation	NOUN
bjp-62725	34	11	of	of	ADP
bjp-62725	34	12	β	β	NOUN
bjp-62725	34	13	-	-	NOUN
bjp-62725	34	14	catenin	catenin	NOUN
bjp-62725	34	15	,	,	PUNCT
bjp-62725	34	16	which	which	PRON
bjp-62725	34	17	accumulates	accumulate	VERB
bjp-62725	34	18	in	in	ADP
bjp-62725	34	19	the	the	DET
bjp-62725	34	20	cytoplasm	cytoplasm	NOUN
bjp-62725	34	21	and	and	CCONJ
bjp-62725	34	22	migrates	migrate	VERB
bjp-62725	34	23	to	to	ADP
bjp-62725	34	24	the	the	DET
bjp-62725	34	25	nucleus	nucleus	NOUN
bjp-62725	34	26	(	(	PUNCT
bjp-62725	34	27	zhang	zhang	PROPN
bjp-62725	34	28	and	and	CCONJ
bjp-62725	34	29	wang	wang	PROPN
bjp-62725	34	30	,	,	PUNCT
bjp-62725	34	31	2020	2020	NUM
bjp-62725	34	32	)	)	PUNCT
bjp-62725	34	33	.	.	PUNCT
bjp-62725	35	1	the	the	DET
bjp-62725	35	2	study	study	NOUN
bjp-62725	35	3	shows	show	VERB
bjp-62725	35	4	that	that	SCONJ
bjp-62725	35	5	the	the	DET
bjp-62725	35	6	regulation	regulation	NOUN
bjp-62725	35	7	of	of	ADP
bjp-62725	35	8	wnt	wnt	PROPN
bjp-62725	35	9	/	/	SYM
bjp-62725	35	10	β	β	NOUN
bjp-62725	35	11	-	-	ADJ
bjp-62725	35	12	catenin	catenin	ADJ
bjp-62725	35	13	signaling	signaling	NOUN
bjp-62725	35	14	affects	affect	VERB
bjp-62725	35	15	the	the	DET
bjp-62725	35	16	differentiation	differentiation	NOUN
bjp-62725	35	17	of	of	ADP
bjp-62725	35	18	chondrocytes	chondrocyte	NOUN
bjp-62725	35	19	(	(	PUNCT
bjp-62725	35	20	yu	yu	X
bjp-62725	35	21	et	et	PROPN
bjp-62725	35	22	al	al	PROPN
bjp-62725	35	23	.	.	PROPN
bjp-62725	35	24	,	,	PUNCT
bjp-62725	35	25	2019	2019	NUM
bjp-62725	35	26	)	)	PUNCT
bjp-62725	35	27	.	.	PUNCT
bjp-62725	36	1	additionally	additionally	ADV
bjp-62725	36	2	,	,	PUNCT
bjp-62725	36	3	it	it	PRON
bjp-62725	36	4	was	be	AUX
bjp-62725	36	5	discovered	discover	VERB
bjp-62725	36	6	that	that	SCONJ
bjp-62725	36	7	osteoarthritis	osteoarthritis	NOUN
bjp-62725	36	8	patients	patient	NOUN
bjp-62725	36	9	have	have	AUX
bjp-62725	36	10	activated	activate	VERB
bjp-62725	36	11	βcatenin	βcatenin	ADJ
bjp-62725	36	12	signaling	signal	VERB
bjp-62725	36	13	(	(	PUNCT
bjp-62725	36	14	fernández	fernández	NOUN
bjp-62725	36	15	-	-	PUNCT
bjp-62725	36	16	torres	torres	PROPN
bjp-62725	36	17	et	et	PROPN
bjp-62725	36	18	al	al	PROPN
bjp-62725	36	19	.	.	PROPN
bjp-62725	36	20	,	,	PUNCT
bjp-62725	36	21	2018	2018	NUM
bjp-62725	36	22	;	;	PUNCT
bjp-62725	36	23	li	li	PROPN
bjp-62725	36	24	et	et	PROPN
bjp-62725	36	25	al	al	PROPN
bjp-62725	36	26	.	.	PROPN
bjp-62725	36	27	,	,	PUNCT
bjp-62725	36	28	2020	2020	NUM
bjp-62725	36	29	)	)	PUNCT
bjp-62725	36	30	.	.	PUNCT
bjp-62725	37	1	in	in	ADP
bjp-62725	37	2	light	light	NOUN
bjp-62725	37	3	of	of	ADP
bjp-62725	37	4	this	this	PRON
bjp-62725	37	5	,	,	PUNCT
bjp-62725	37	6	chondrocyte	chondrocyte	NOUN
bjp-62725	37	7	differentiation	differentiation	NOUN
bjp-62725	37	8	and	and	CCONJ
bjp-62725	37	9	the	the	DET
bjp-62725	37	10	pathogenic	pathogenic	ADJ
bjp-62725	37	11	processes	process	NOUN
bjp-62725	37	12	of	of	ADP
bjp-62725	37	13	osteoarthritis	osteoarthritis	NOUN
bjp-62725	37	14	depend	depend	VERB
bjp-62725	37	15	on	on	ADP
bjp-62725	37	16	wnt	wnt	PROPN
bjp-62725	37	17	/	/	SYM
bjp-62725	37	18	β	β	NOUN
bjp-62725	37	19	-	-	ADJ
bjp-62725	37	20	catenin	catenin	ADJ
bjp-62725	37	21	signaling	signaling	NOUN
bjp-62725	37	22	.	.	PUNCT
bjp-62725	38	1	nuclear	nuclear	ADJ
bjp-62725	38	2	factor	factor	NOUN
bjp-62725	38	3	kappa	kappa	PROPN
bjp-62725	38	4	b	b	PROPN
bjp-62725	38	5	(	(	PUNCT
bjp-62725	38	6	nf	nf	NOUN
bjp-62725	38	7	-	-	PUNCT
bjp-62725	38	8	κb	κb	NOUN
bjp-62725	38	9	)	)	PUNCT
bjp-62725	38	10	exists	exist	VERB
bjp-62725	38	11	in	in	ADP
bjp-62725	38	12	the	the	DET
bjp-62725	38	13	cytoplasm	cytoplasm	NOUN
bjp-62725	38	14	with	with	ADP
bjp-62725	38	15	heterodimer	heterodimer	NOUN
bjp-62725	38	16	inhibitor	inhibitor	NOUN
bjp-62725	38	17	protein	protein	NOUN
bjp-62725	38	18	of	of	ADP
bjp-62725	38	19	p50	p50	NOUN
bjp-62725	38	20	and	and	CCONJ
bjp-62725	38	21	p65	p65	NOUN
bjp-62725	38	22	,	,	PUNCT
bjp-62725	38	23	known	know	VERB
bjp-62725	38	24	as	as	ADP
bjp-62725	38	25	a	a	DET
bjp-62725	38	26	inhibitor	inhibitor	NOUN
bjp-62725	38	27	of	of	ADP
bjp-62725	38	28	nf	nf	NOUN
bjp-62725	38	29	-	-	PUNCT
bjp-62725	38	30	κb	κb	ADJ
bjp-62725	38	31	(	(	PUNCT
bjp-62725	38	32	iκb	iκb	PROPN
bjp-62725	38	33	)	)	PUNCT
bjp-62725	38	34	(	(	PUNCT
bjp-62725	38	35	zhang	zhang	X
bjp-62725	38	36	et	et	PROPN
bjp-62725	38	37	al	al	PROPN
bjp-62725	38	38	.	.	PROPN
bjp-62725	38	39	,	,	PUNCT
bjp-62725	38	40	2021	2021	NUM
bjp-62725	38	41	)	)	PUNCT
bjp-62725	38	42	.	.	PUNCT
bjp-62725	39	1	nearly	nearly	ADV
bjp-62725	39	2	all	all	DET
bjp-62725	39	3	cell	cell	NOUN
bjp-62725	39	4	types	type	NOUN
bjp-62725	39	5	have	have	VERB
bjp-62725	39	6	nf	nf	NOUN
bjp-62725	39	7	-	-	PUNCT
bjp-62725	39	8	b	b	NOUN
bjp-62725	39	9	,	,	PUNCT
bjp-62725	39	10	which	which	PRON
bjp-62725	39	11	is	be	AUX
bjp-62725	39	12	essential	essential	ADJ
bjp-62725	39	13	for	for	ADP
bjp-62725	39	14	controlling	control	VERB
bjp-62725	39	15	inflammatory	inflammatory	ADJ
bjp-62725	39	16	responses	response	NOUN
bjp-62725	39	17	.	.	PUNCT
bjp-62725	40	1	ikb	ikb	VERB
bjp-62725	40	2	and	and	CCONJ
bjp-62725	40	3	homoor	homoor	PROPN
bjp-62725	40	4	heterodimers	heterodimer	NOUN
bjp-62725	40	5	of	of	ADP
bjp-62725	40	6	nf	nf	ADJ
bjp-62725	40	7	-	-	PUNCT
bjp-62725	40	8	κb	κb	NOUN
bjp-62725	40	9	combine	combine	NOUN
bjp-62725	40	10	in	in	ADP
bjp-62725	40	11	the	the	DET
bjp-62725	40	12	cytoplasm	cytoplasm	NOUN
bjp-62725	40	13	when	when	SCONJ
bjp-62725	40	14	there	there	PRON
bjp-62725	40	15	is	be	VERB
bjp-62725	40	16	no	no	DET
bjp-62725	40	17	stimulation	stimulation	NOUN
bjp-62725	40	18	.	.	PUNCT
bjp-62725	41	1	however	however	ADV
bjp-62725	41	2	,	,	PUNCT
bjp-62725	41	3	ib	ib	PROPN
bjp-62725	41	4	kinases	kinase	NOUN
bjp-62725	41	5	(	(	PUNCT
bjp-62725	41	6	(	(	PUNCT
bjp-62725	41	7	ikkα	ikkα	NOUN
bjp-62725	41	8	,	,	PUNCT
bjp-62725	41	9	ikkβ	ikkβ	ADJ
bjp-62725	41	10	,	,	PUNCT
bjp-62725	41	11	and	and	CCONJ
bjp-62725	41	12	ikkλ	ikkλ	ADJ
bjp-62725	41	13	)	)	PUNCT
bjp-62725	41	14	phosphorylate	phosphorylate	VERB
bjp-62725	41	15	iκb	iκb	NOUN
bjp-62725	41	16	,	,	PUNCT
bjp-62725	41	17	as	as	ADP
bjp-62725	41	18	a	a	DET
bjp-62725	41	19	result	result	NOUN
bjp-62725	41	20	of	of	ADP
bjp-62725	41	21	numerous	numerous	ADJ
bjp-62725	41	22	stress	stress	NOUN
bjp-62725	41	23	-	-	PUNCT
bjp-62725	41	24	inducing	induce	VERB
bjp-62725	41	25	substances	substance	NOUN
bjp-62725	41	26	including	include	VERB
bjp-62725	41	27	cytokines	cytokine	NOUN
bjp-62725	41	28	,	,	PUNCT
bjp-62725	41	29	lps	lps	PROPN
bjp-62725	41	30	,	,	PUNCT
bjp-62725	41	31	or	or	CCONJ
bjp-62725	41	32	ros	ros	PROPN
bjp-62725	41	33	,	,	PUNCT
bjp-62725	41	34	which	which	PRON
bjp-62725	41	35	causes	cause	VERB
bjp-62725	41	36	iκb	iκb	NOUN
bjp-62725	41	37	to	to	PART
bjp-62725	41	38	be	be	AUX
bjp-62725	41	39	ubiquitylated	ubiquitylated	ADJ
bjp-62725	41	40	and	and	CCONJ
bjp-62725	41	41	degraded	degrade	VERB
bjp-62725	41	42	by	by	ADP
bjp-62725	41	43	the	the	DET
bjp-62725	41	44	proteasome	proteasome	NOUN
bjp-62725	41	45	(	(	PUNCT
bjp-62725	41	46	zhang	zhang	PROPN
bjp-62725	41	47	et	et	PROPN
bjp-62725	41	48	al	al	PROPN
bjp-62725	41	49	.	.	PROPN
bjp-62725	41	50	,	,	PUNCT
bjp-62725	41	51	2021	2021	NUM
bjp-62725	41	52	)	)	PUNCT
bjp-62725	41	53	and	and	CCONJ
bjp-62725	41	54	has	have	AUX
bjp-62725	41	55	been	be	AUX
bjp-62725	41	56	linked	link	VERB
bjp-62725	41	57	to	to	ADP
bjp-62725	41	58	various	various	ADJ
bjp-62725	41	59	diseases	disease	NOUN
bjp-62725	41	60	including	include	VERB
bjp-62725	41	61	arthritis	arthritis	NOUN
bjp-62725	41	62	(	(	PUNCT
bjp-62725	41	63	malkowski	malkowski	PROPN
bjp-62725	41	64	,	,	PUNCT
bjp-62725	41	65	2011	2011	NUM
bjp-62725	41	66	;	;	PUNCT
bjp-62725	41	67	wang	wang	PROPN
bjp-62725	41	68	et	et	PROPN
bjp-62725	41	69	al	al	PROPN
bjp-62725	41	70	.	.	PROPN
bjp-62725	41	71	,	,	PUNCT
bjp-62725	41	72	2021	2021	NUM
bjp-62725	41	73	;	;	PUNCT
bjp-62725	41	74	pannunzio	pannunzio	NOUN
bjp-62725	41	75	et	et	PROPN
bjp-62725	41	76	al	al	PROPN
bjp-62725	41	77	.	.	PROPN
bjp-62725	41	78	,	,	PUNCT
bjp-62725	41	79	2018	2018	NUM
bjp-62725	41	80	;	;	PUNCT
bjp-62725	41	81	ferrer	ferrer	PROPN
bjp-62725	41	82	et	et	PROPN
bjp-62725	41	83	al	al	PROPN
bjp-62725	41	84	.	.	PROPN
bjp-62725	41	85	,	,	PUNCT
bjp-62725	41	86	2019	2019	NUM
bjp-62725	41	87	)	)	PUNCT
bjp-62725	41	88	.	.	PUNCT
bjp-62725	42	1	this	this	DET
bjp-62725	42	2	research	research	NOUN
bjp-62725	42	3	looked	look	VERB
bjp-62725	42	4	into	into	ADP
bjp-62725	42	5	how	how	SCONJ
bjp-62725	42	6	the	the	DET
bjp-62725	42	7	microtubule	microtubule	NOUN
bjp-62725	42	8	changes	change	VERB
bjp-62725	42	9	in	in	ADP
bjp-62725	42	10	primary	primary	ADJ
bjp-62725	42	11	articular	articular	ADJ
bjp-62725	42	12	chondrocytes	chondrocyte	NOUN
bjp-62725	42	13	regulate	regulate	VERB
bjp-62725	42	14	chondrocyte	chondrocyte	NOUN
bjp-62725	42	15	development	development	NOUN
bjp-62725	42	16	and	and	CCONJ
bjp-62725	42	17	the	the	DET
bjp-62725	42	18	inflammatory	inflammatory	ADJ
bjp-62725	42	19	response	response	NOUN
bjp-62725	42	20	.	.	PUNCT
bjp-62725	43	1	materials	material	NOUN
bjp-62725	43	2	and	and	CCONJ
bjp-62725	43	3	methods	method	NOUN
bjp-62725	43	4	articular	articular	VERB
bjp-62725	43	5	chondrocyte	chondrocyte	NOUN
bjp-62725	43	6	culture	culture	NOUN
bjp-62725	43	7	and	and	CCONJ
bjp-62725	43	8	maintenance	maintenance	NOUN
bjp-62725	43	9	primary	primary	ADJ
bjp-62725	43	10	articular	articular	ADJ
bjp-62725	43	11	chondrocytes	chondrocyte	NOUN
bjp-62725	43	12	were	be	AUX
bjp-62725	43	13	isolated	isolate	VERB
bjp-62725	43	14	from	from	ADP
bjp-62725	43	15	rabbit	rabbit	NOUN
bjp-62725	43	16	articular	articular	ADJ
bjp-62725	43	17	cartilages	cartilage	NOUN
bjp-62725	43	18	which	which	PRON
bjp-62725	43	19	were	be	AUX
bjp-62725	43	20	cultured	cultured	ADJ
bjp-62725	43	21	and	and	CCONJ
bjp-62725	43	22	maintained	maintain	VERB
bjp-62725	43	23	by	by	ADP
bjp-62725	43	24	using	use	VERB
bjp-62725	43	25	the	the	DET
bjp-62725	43	26	reported	report	VERB
bjp-62725	43	27	protocol	protocol	NOUN
bjp-62725	43	28	(	(	PUNCT
bjp-62725	43	29	han	han	PROPN
bjp-62725	43	30	et	et	PROPN
bjp-62725	43	31	al	al	PROPN
bjp-62725	43	32	.	.	PROPN
bjp-62725	43	33	,	,	PUNCT
bjp-62725	43	34	2022	2022	NUM
bjp-62725	43	35	)	)	PUNCT
bjp-62725	43	36	.	.	PUNCT
bjp-62725	44	1	colchicine	colchicine	PROPN
bjp-62725	44	2	(	(	PUNCT
bjp-62725	44	3	cas:64	cas:64	PROPN
bjp-62725	44	4	-	-	PUNCT
bjp-62725	44	5	86	86	NUM
bjp-62725	44	6	-	-	PUNCT
bjp-62725	44	7	8)	8)	NUM
bjp-62725	44	8	and	and	CCONJ
bjp-62725	44	9	paclitaxel	paclitaxel	PROPN
bjp-62725	44	10	(	(	PUNCT
bjp-62725	44	11	cas	cas	PROPN
bjp-62725	44	12	:	:	PUNCT
bjp-62725	44	13	333069	333069	NUM
bjp-62725	44	14	-	-	SYM
bjp-62725	44	15	62	62	NUM
bjp-62725	44	16	-	-	SYM
bjp-62725	44	17	4	4	NUM
bjp-62725	44	18	)	)	PUNCT
bjp-62725	44	19	were	be	AUX
bjp-62725	44	20	brought	bring	VERB
bjp-62725	44	21	from	from	ADP
bjp-62725	44	22	sigma	sigma	PROPN
bjp-62725	44	23	aldrich	aldrich	PROPN
bjp-62725	44	24	and	and	CCONJ
bjp-62725	44	25	were	be	AUX
bjp-62725	44	26	added	add	VERB
bjp-62725	44	27	to	to	ADP
bjp-62725	44	28	the	the	DET
bjp-62725	44	29	cell	cell	NOUN
bjp-62725	44	30	medium	medium	NOUN
bjp-62725	44	31	when	when	SCONJ
bjp-62725	44	32	the	the	DET
bjp-62725	44	33	density	density	NOUN
bjp-62725	44	34	of	of	ADP
bjp-62725	44	35	the	the	DET
bjp-62725	44	36	cells	cell	NOUN
bjp-62725	44	37	reached	reach	VERB
bjp-62725	44	38	80	80	NUM
bjp-62725	44	39	%	%	NOUN
bjp-62725	44	40	population	population	NOUN
bjp-62725	44	41	.	.	PUNCT
bjp-62725	45	1	rna	rna	NOUN
bjp-62725	45	2	expression	expression	NOUN
bjp-62725	45	3	quantification	quantification	NOUN
bjp-62725	45	4	the	the	DET
bjp-62725	45	5	protocol	protocol	NOUN
bjp-62725	45	6	followed	follow	VERB
bjp-62725	45	7	for	for	ADP
bjp-62725	45	8	rna	rna	NOUN
bjp-62725	45	9	extraction	extraction	NOUN
bjp-62725	45	10	,	,	PUNCT
bjp-62725	45	11	and	and	CCONJ
bjp-62725	45	12	rna	rna	NOUN
bjp-62725	45	13	to	to	ADP
bjp-62725	45	14	dna	dna	PROPN
bjp-62725	45	15	amplification	amplification	NOUN
bjp-62725	45	16	are	be	AUX
bjp-62725	45	17	reported	report	VERB
bjp-62725	45	18	elsewhere	elsewhere	ADV
bjp-62725	45	19	(	(	PUNCT
bjp-62725	45	20	han	han	PROPN
bjp-62725	45	21	et	et	PROPN
bjp-62725	45	22	al	al	PROPN
bjp-62725	45	23	.	.	PROPN
bjp-62725	45	24	,	,	PUNCT
bjp-62725	45	25	2022	2022	NUM
bjp-62725	45	26	)	)	PUNCT
bjp-62725	45	27	.	.	PUNCT
bjp-62725	46	1	the	the	DET
bjp-62725	46	2	primers	primer	NOUN
bjp-62725	46	3	used	use	VERB
bjp-62725	46	4	to	to	PART
bjp-62725	46	5	quantify	quantify	VERB
bjp-62725	46	6	the	the	DET
bjp-62725	46	7	expression	expression	NOUN
bjp-62725	46	8	were	be	AUX
bjp-62725	46	9	:	:	PUNCT
bjp-62725	46	10	cyclooxygenase-2	cyclooxygenase-2	NUM
bjp-62725	46	11	(	(	PUNCT
bjp-62725	46	12	cox-2	cox-2	NOUN
bjp-62725	46	13	)	)	PUNCT
bjp-62725	46	14	(	(	PUNCT
bjp-62725	46	15	298	298	NUM
bjp-62725	46	16	-	-	PUNCT
bjp-62725	46	17	bps	bps	NOUN
bjp-62725	46	18	)	)	PUNCT
bjp-62725	46	19	,	,	PUNCT
bjp-62725	46	20	5′-tcagccacgcagcaaatcct-3′	5′-tcagccacgcagcaaatcct-3′	NUM
bjp-62725	46	21	(	(	PUNCT
bjp-62725	46	22	sense	sense	NOUN
bjp-62725	46	23	)	)	PUNCT
bjp-62725	46	24	and	and	CCONJ
bjp-62725	46	25	5′-gtgatctggatgtcagcacg-3′	5′-gtgatctggatgtcagcacg-3′	NUM
bjp-62725	46	26	(	(	PUNCT
bjp-62725	46	27	antisense	antisense	NOUN
bjp-62725	46	28	)	)	PUNCT
bjp-62725	46	29	,	,	PUNCT
bjp-62725	46	30	glyceraldehyde	glyceraldehyde	NOUN
bjp-62725	46	31	3phosphate	3phosphate	NUM
bjp-62725	46	32	dehydrogenase	dehydrogenase	NOUN
bjp-62725	46	33	(	(	PUNCT
bjp-62725	46	34	gapdh	gapdh	NOUN
bjp-62725	46	35	;	;	PUNCT
bjp-62725	46	36	299	299	NUM
bjp-62725	46	37	-	-	PUNCT
bjp-62725	46	38	bps	bps	NOUN
bjp-62725	46	39	)	)	PUNCT
bjp-62725	46	40	,	,	PUNCT
bjp-62725	46	41	5'-tcaccatcttccaggagc	5'-tcaccatcttccaggagc	NUM
bjp-62725	46	42	ga-3	ga-3	NOUN
bjp-62725	46	43	'	'	PART
bjp-62725	46	44	(	(	PUNCT
bjp-62725	46	45	sense	sense	NOUN
bjp-62725	46	46	)	)	PUNCT
bjp-62725	46	47	and	and	CCONJ
bjp-62725	46	48	5'-cacaatgccgaagtggtcgt-3	5'-cacaatgccgaagtggtcgt-3	NUM
bjp-62725	46	49	'	'	PUNCT
bjp-62725	46	50	(	(	PUNCT
bjp-62725	46	51	antisense	antisense	NOUN
bjp-62725	46	52	)	)	PUNCT
bjp-62725	46	53	,	,	PUNCT
bjp-62725	46	54	tubulin	tubulin	NOUN
bjp-62725	46	55	(	(	PUNCT
bjp-62725	46	56	296bps	296bps	NUM
bjp-62725	46	57	)	)	PUNCT
bjp-62725	46	58	,	,	PUNCT
bjp-62725	46	59	5'-gcactctgattgtgccttca-3	5'-gcactctgattgtgccttca-3	NUM
bjp-62725	46	60	'	'	PART
bjp-62725	46	61	(	(	PUNCT
bjp-62725	46	62	sense	sense	NOUN
bjp-62725	46	63	)	)	PUNCT
bjp-62725	46	64	and	and	CCONJ
bjp-62725	46	65	5'-aggcattggtgatctctgct-3	5'-aggcattggtgatctctgct-3	NUM
bjp-62725	46	66	'	'	PUNCT
bjp-62725	46	67	(	(	PUNCT
bjp-62725	46	68	antisense	antisense	NOUN
bjp-62725	46	69	)	)	PUNCT
bjp-62725	46	70	and	and	CCONJ
bjp-62725	46	71	type	type	PROPN
bjp-62725	46	72	ii	ii	PROPN
bjp-62725	46	73	collagen	collagen	NOUN
bjp-62725	46	74	(	(	PUNCT
bjp-62725	46	75	370	370	NUM
bjp-62725	46	76	-	-	PUNCT
bjp-62725	46	77	bps	bps	NOUN
bjp-62725	46	78	)	)	PUNCT
bjp-62725	46	79	,	,	PUNCT
bjp-62725	46	80	5'-gaccccatgcagtacatg	5'-gaccccatgcagtacatg	NUM
bjp-62725	46	81	cg-3	cg-3	NOUN
bjp-62725	46	82	'	'	PUNCT
bjp-62725	46	83	(	(	PUNCT
bjp-62725	46	84	sense	sense	NOUN
bjp-62725	46	85	)	)	PUNCT
bjp-62725	46	86	and	and	CCONJ
bjp-62725	46	87	5'-agccgccattgatggtctcc-3	5'-agccgccattgatggtctcc-3	NUM
bjp-62725	46	88	'	'	PUNCT
bjp-62725	46	89	(	(	PUNCT
bjp-62725	46	90	antisense	antisense	NOUN
bjp-62725	46	91	)	)	PUNCT
bjp-62725	46	92	.	.	PUNCT
bjp-62725	47	1	1%agarose	1%agarose	NUM
bjp-62725	47	2	gel	gel	NOUN
bjp-62725	47	3	was	be	AUX
bjp-62725	47	4	used	use	VERB
bjp-62725	47	5	to	to	PART
bjp-62725	47	6	analyse	analyse	VERB
bjp-62725	47	7	samples	sample	NOUN
bjp-62725	47	8	obtained	obtain	VERB
bjp-62725	47	9	from	from	ADP
bjp-62725	47	10	amplification	amplification	NOUN
bjp-62725	47	11	.	.	PUNCT
bjp-62725	48	1	transfection	transfection	NOUN
bjp-62725	48	2	sirna	sirna	PROPN
bjp-62725	48	3	of	of	ADP
bjp-62725	48	4	β	β	PROPN
bjp-62725	48	5	-	-	ADJ
bjp-62725	48	6	catenin	catenin	ADJ
bjp-62725	48	7	sirna	sirna	PROPN
bjp-62725	48	8	was	be	AUX
bjp-62725	48	9	transduced	transduce	VERB
bjp-62725	48	10	in	in	ADP
bjp-62725	48	11	chondrocytes	chondrocyte	NOUN
bjp-62725	48	12	by	by	ADP
bjp-62725	48	13	mixing	mix	VERB
bjp-62725	48	14	pure	pure	ADJ
bjp-62725	48	15	dmem	dmem	VERB
bjp-62725	48	16	with	with	ADP
bjp-62725	48	17	turbofect	turbofect	NOUN
bjp-62725	48	18	transfection	transfection	NOUN
bjp-62725	48	19	agent	agent	NOUN
bjp-62725	48	20	obtained	obtain	VERB
bjp-62725	48	21	from	from	ADP
bjp-62725	48	22	thermofisher	thermofisher	ADJ
bjp-62725	48	23	scientific	scientific	NOUN
bjp-62725	48	24	.	.	PUNCT
bjp-62725	49	1	the	the	DET
bjp-62725	49	2	sirna	sirna	PROPN
bjp-62725	49	3	sequences	sequence	NOUN
bjp-62725	49	4	were	be	AUX
bjp-62725	49	5	:	:	PUNCT
bjp-62725	49	6	negative	negative	ADJ
bjp-62725	49	7	control	control	NOUN
bjp-62725	49	8	(	(	PUNCT
bjp-62725	49	9	nc	nc	PROPN
bjp-62725	49	10	)	)	PUNCT
bjp-62725	49	11	s	s	PART
bjp-62725	49	12	irna	irna	ADJ
bjp-62725	49	13	5	5	NUM
bjp-62725	49	14	'	'	PUNCT
bjp-62725	49	15	-acgugacacguucggagaatt	-acgugacacguucggagaatt	NOUN
bjp-62725	49	16	3	3	NUM
bjp-62725	49	17	'	'	PUNCT
bjp-62725	49	18	(	(	PUNCT
bjp-62725	49	19	antisense	antisense	NOUN
bjp-62725	49	20	)	)	PUNCT
bjp-62725	49	21	and	and	CCONJ
bjp-62725	49	22	5'-uucuccgaacgugucacgutt3	5'-uucuccgaacgugucacgutt3	NUM
bjp-62725	49	23	'	'	PART
bjp-62725	49	24	(	(	PUNCT
bjp-62725	49	25	sense	sense	NOUN
bjp-62725	49	26	)	)	PUNCT
bjp-62725	49	27	,	,	PUNCT
bjp-62725	49	28	β	β	X
bjp-62725	49	29	-	-	ADJ
bjp-62725	49	30	catenin	catenin	ADJ
bjp-62725	49	31	sirna	sirna	PROPN
bjp-62725	49	32	,	,	PUNCT
bjp-62725	49	33	5'-auuuauaucaucugaaccctt-3	5'-auuuauaucaucugaaccctt-3	NUM
bjp-62725	49	34	'	'	PUNCT
bjp-62725	49	35	(	(	PUNCT
bjp-62725	49	36	antisense	antisense	NOUN
bjp-62725	49	37	)	)	PUNCT
bjp-62725	49	38	and	and	CCONJ
bjp-62725	50	1	5'-ggguucagaugauauaaautt-3	5'-ggguucagaugauauaaautt-3	NUM
bjp-62725	50	2	(	(	PUNCT
bjp-62725	50	3	sense	sense	NOUN
bjp-62725	50	4	)	)	PUNCT
bjp-62725	50	5	.	.	PUNCT
bjp-62725	51	1	alcian	alcian	PROPN
bjp-62725	51	2	blue	blue	ADJ
bjp-62725	51	3	staining	stain	VERB
bjp-62725	51	4	cells	cell	NOUN
bjp-62725	51	5	fixation	fixation	NOUN
bjp-62725	51	6	was	be	AUX
bjp-62725	51	7	done	do	VERB
bjp-62725	51	8	with	with	ADP
bjp-62725	51	9	3.5	3.5	NUM
bjp-62725	51	10	%	%	NOUN
bjp-62725	51	11	of	of	ADP
bjp-62725	51	12	formaldehyde	formaldehyde	NOUN
bjp-62725	51	13	solution	solution	NOUN
bjp-62725	51	14	which	which	PRON
bjp-62725	51	15	was	be	AUX
bjp-62725	51	16	then	then	ADV
bjp-62725	51	17	cleaned	clean	VERB
bjp-62725	51	18	thrice	thrice	NOUN
bjp-62725	51	19	with	with	ADP
bjp-62725	51	20	1x	1x	NUM
bjp-62725	51	21	phosphate	phosphate	ADJ
bjp-62725	51	22	saline	saline	NOUN
bjp-62725	51	23	buffer	buffer	NOUN
bjp-62725	51	24	followed	follow	VERB
bjp-62725	51	25	by	by	ADP
bjp-62725	51	26	the	the	DET
bjp-62725	51	27	introduction	introduction	NOUN
bjp-62725	51	28	of	of	ADP
bjp-62725	51	29	alcian	alcian	ADJ
bjp-62725	51	30	blue	blue	ADJ
bjp-62725	51	31	stain	stain	NOUN
bjp-62725	51	32	.	.	PUNCT
bjp-62725	52	1	the	the	DET
bjp-62725	52	2	stained	stain	VERB
bjp-62725	52	3	cells	cell	NOUN
bjp-62725	52	4	are	be	AUX
bjp-62725	52	5	incubated	incubate	VERB
bjp-62725	52	6	for	for	ADP
bjp-62725	52	7	overnight	overnight	ADV
bjp-62725	52	8	and	and	CCONJ
bjp-62725	52	9	then	then	ADV
bjp-62725	52	10	washed	wash	VERB
bjp-62725	52	11	with	with	ADP
bjp-62725	52	12	1x	1x	NUM
bjp-62725	52	13	phosphate	phosphate	ADJ
bjp-62725	52	14	saline	saline	NOUN
bjp-62725	52	15	buffer	buffer	NOUN
bjp-62725	52	16	and	and	CCONJ
bjp-62725	52	17	then	then	ADV
bjp-62725	52	18	quantified	quantify	VERB
bjp-62725	52	19	with	with	ADP
bjp-62725	52	20	elisa	elisa	NOUN
bjp-62725	52	21	plate	plate	NOUN
bjp-62725	52	22	analyzer	analyzer	NOUN
bjp-62725	52	23	at	at	ADP
bjp-62725	52	24	595	595	NUM
bjp-62725	52	25	nm	nm	NOUN
bjp-62725	52	26	(	(	PUNCT
bjp-62725	52	27	han	han	PROPN
bjp-62725	52	28	et	et	PROPN
bjp-62725	52	29	al	al	PROPN
bjp-62725	52	30	.	.	PROPN
bjp-62725	52	31	,	,	PUNCT
bjp-62725	52	32	2022	2022	NUM
bjp-62725	52	33	)	)	PUNCT
bjp-62725	52	34	.	.	PUNCT
bjp-62725	53	1	immunofluorescence	immunofluorescence	NOUN
bjp-62725	53	2	analysis	analysis	NOUN
bjp-62725	53	3	the	the	DET
bjp-62725	53	4	cells	cell	NOUN
bjp-62725	53	5	are	be	AUX
bjp-62725	53	6	fixated	fixated	ADJ
bjp-62725	53	7	and	and	CCONJ
bjp-62725	53	8	permeabilized	permeabilize	VERB
bjp-62725	53	9	with	with	ADP
bjp-62725	53	10	3.5	3.5	NUM
bjp-62725	53	11	%	%	NOUN
bjp-62725	53	12	paraformaldehyde	paraformaldehyde	NOUN
bjp-62725	53	13	and	and	CCONJ
bjp-62725	53	14	0.1	0.1	NUM
bjp-62725	53	15	%	%	NOUN
bjp-62725	53	16	of	of	ADP
bjp-62725	53	17	triton	triton	PROPN
bjp-62725	53	18	x-100	x-100	PROPN
bjp-62725	53	19	and	and	CCONJ
bjp-62725	53	20	then	then	ADV
bjp-62725	53	21	washed	wash	VERB
bjp-62725	53	22	with	with	ADP
bjp-62725	53	23	1x	1x	NUM
bjp-62725	53	24	phosphate	phosphate	ADJ
bjp-62725	53	25	saline	saline	NOUN
bjp-62725	53	26	buffer	buffer	NOUN
bjp-62725	53	27	.	.	PUNCT
bjp-62725	54	1	the	the	DET
bjp-62725	54	2	primary	primary	ADJ
bjp-62725	54	3	antibodies	antibody	NOUN
bjp-62725	54	4	were	be	AUX
bjp-62725	54	5	added	add	VERB
bjp-62725	54	6	to	to	ADP
bjp-62725	54	7	the	the	DET
bjp-62725	54	8	cells	cell	NOUN
bjp-62725	54	9	which	which	PRON
bjp-62725	54	10	are	be	AUX
bjp-62725	54	11	type	type	NOUN
bjp-62725	54	12	ii	ii	NOUN
bjp-62725	54	13	collagen	collagen	NOUN
bjp-62725	54	14	and	and	CCONJ
bjp-62725	54	15	β	β	NOUN
bjp-62725	54	16	-	-	NOUN
bjp-62725	54	17	catenin	catenin	NOUN
bjp-62725	54	18	and	and	CCONJ
bjp-62725	54	19	incubated	incubate	VERB
bjp-62725	54	20	for	for	ADP
bjp-62725	54	21	24	24	NUM
bjp-62725	54	22	hours	hour	NOUN
bjp-62725	54	23	.	.	PUNCT
bjp-62725	55	1	after	after	ADP
bjp-62725	55	2	that	that	PRON
bjp-62725	55	3	,	,	PUNCT
bjp-62725	55	4	cells	cell	NOUN
bjp-62725	55	5	were	be	AUX
bjp-62725	55	6	washed	wash	VERB
bjp-62725	55	7	with	with	ADP
bjp-62725	55	8	1x	1x	NUM
bjp-62725	55	9	phosphate	phosphate	ADJ
bjp-62725	55	10	saline	saline	NOUN
bjp-62725	55	11	buffer	buffer	NOUN
bjp-62725	55	12	and	and	CCONJ
bjp-62725	55	13	secondary	secondary	ADJ
bjp-62725	55	14	fluorescent	fluorescent	NOUN
bjp-62725	55	15	antibodies	antibody	NOUN
bjp-62725	55	16	were	be	AUX
bjp-62725	55	17	added	add	VERB
bjp-62725	55	18	.	.	PUNCT
bjp-62725	56	1	the	the	DET
bjp-62725	56	2	results	result	NOUN
bjp-62725	56	3	were	be	AUX
bjp-62725	56	4	then	then	ADV
bjp-62725	56	5	visualized	visualize	VERB
bjp-62725	56	6	with	with	ADP
bjp-62725	56	7	a	a	DET
bjp-62725	56	8	fluorescent	fluorescent	ADJ
bjp-62725	56	9	microscopy	microscopy	NOUN
bjp-62725	56	10	(	(	PUNCT
bjp-62725	56	11	han	han	PROPN
bjp-62725	56	12	et	et	PROPN
bjp-62725	56	13	al	al	PROPN
bjp-62725	56	14	.	.	PROPN
bjp-62725	56	15	,	,	PUNCT
bjp-62725	56	16	2018	2018	NUM
bjp-62725	56	17	)	)	PUNCT
bjp-62725	56	18	.	.	PUNCT
bjp-62725	57	1	statistical	statistical	ADJ
bjp-62725	57	2	analysis	analysis	NOUN
bjp-62725	57	3	analysis	analysis	NOUN
bjp-62725	57	4	of	of	ADP
bjp-62725	57	5	variance	variance	NOUN
bjp-62725	57	6	(	(	PUNCT
bjp-62725	57	7	anova	anova	PROPN
bjp-62725	57	8	)	)	PUNCT
bjp-62725	57	9	was	be	AUX
bjp-62725	57	10	used	use	VERB
bjp-62725	57	11	to	to	PART
bjp-62725	57	12	assess	assess	VERB
bjp-62725	57	13	the	the	DET
bjp-62725	57	14	statistical	statistical	ADJ
bjp-62725	57	15	significance	significance	NOUN
bjp-62725	57	16	of	of	ADP
bjp-62725	57	17	the	the	DET
bjp-62725	57	18	difference	difference	NOUN
bjp-62725	57	19	between	between	ADP
bjp-62725	57	20	the	the	DET
bjp-62725	57	21	bangladesh	bangladesh	PROPN
bjp-62725	57	22	j	j	PROPN
bjp-62725	57	23	pharmacol	pharmacol	PROPN
bjp-62725	57	24	2023	2023	NUM
bjp-62725	57	25	;	;	PUNCT
bjp-62725	57	26	18	18	NUM
bjp-62725	57	27	:	:	SYM
bjp-62725	57	28	8	8	NUM
bjp-62725	57	29	-	-	SYM
bjp-62725	57	30	16	16	NUM
bjp-62725	57	31	9	9	NUM
bjp-62725	57	32	control	control	NOUN
bjp-62725	57	33	and	and	CCONJ
bjp-62725	57	34	the	the	DET
bjp-62725	57	35	comparison	comparison	NOUN
bjp-62725	57	36	groups	group	NOUN
bjp-62725	57	37	followed	follow	VERB
bjp-62725	57	38	by	by	ADP
bjp-62725	57	39	tukey	tukey	NOUN
bjp-62725	57	40	's	's	PART
bjp-62725	57	41	multiple	multiple	ADJ
bjp-62725	57	42	comparisons	comparison	NOUN
bjp-62725	57	43	.	.	PUNCT
bjp-62725	58	1	p	p	X
bjp-62725	58	2	-	-	PUNCT
bjp-62725	58	3	value	value	NOUN
bjp-62725	58	4	<	<	NOUN
bjp-62725	58	5	0.05	0.05	NUM
bjp-62725	58	6	was	be	AUX
bjp-62725	58	7	considered	consider	VERB
bjp-62725	58	8	to	to	PART
bjp-62725	58	9	indicate	indicate	VERB
bjp-62725	58	10	statistically	statistically	ADV
bjp-62725	58	11	significant	significant	ADJ
bjp-62725	58	12	differences	difference	NOUN
bjp-62725	58	13	.	.	PUNCT
bjp-62725	59	1	results	result	VERB
bjp-62725	59	2	tubulin	tubulin	NOUN
bjp-62725	59	3	synthesis	synthesis	NOUN
bjp-62725	59	4	and	and	CCONJ
bjp-62725	59	5	chondrocytes	chondrocyte	VERB
bjp-62725	59	6	differentiation	differentiation	VERB
bjp-62725	59	7	the	the	DET
bjp-62725	59	8	effects	effect	NOUN
bjp-62725	59	9	of	of	ADP
bjp-62725	59	10	colchicine	colchicine	PROPN
bjp-62725	59	11	were	be	AUX
bjp-62725	59	12	explored	explore	VERB
bjp-62725	59	13	within	within	ADP
bjp-62725	59	14	the	the	DET
bjp-62725	59	15	concentration	concentration	NOUN
bjp-62725	59	16	of	of	ADP
bjp-62725	59	17	(	(	PUNCT
bjp-62725	59	18	0.1	0.1	NUM
bjp-62725	59	19	-	-	SYM
bjp-62725	59	20	1	1	NUM
bjp-62725	59	21	µm	µm	NOUN
bjp-62725	59	22	)	)	PUNCT
bjp-62725	59	23	in	in	ADP
bjp-62725	59	24	the	the	DET
bjp-62725	59	25	articular	articular	ADJ
bjp-62725	59	26	chondrocytes	chondrocyte	NOUN
bjp-62725	59	27	.	.	PUNCT
bjp-62725	60	1	the	the	DET
bjp-62725	60	2	expression	expression	NOUN
bjp-62725	60	3	of	of	ADP
bjp-62725	60	4	chondrocyte	chondrocyte	NOUN
bjp-62725	60	5	differentiation	differentiation	NOUN
bjp-62725	60	6	markers	marker	NOUN
bjp-62725	60	7	(	(	PUNCT
bjp-62725	60	8	type	type	NOUN
bjp-62725	60	9	ii	ii	PROPN
bjp-62725	60	10	collagen	collagen	NOUN
bjp-62725	60	11	,	,	PUNCT
bjp-62725	60	12	aggrecan	aggrecan	ADJ
bjp-62725	60	13	,	,	PUNCT
bjp-62725	60	14	sox-9	sox-9	PRON
bjp-62725	60	15	,	,	PUNCT
bjp-62725	60	16	cox-2	cox-2	NOUN
bjp-62725	60	17	,	,	PUNCT
bjp-62725	60	18	tubulin	tubulin	NOUN
bjp-62725	60	19	)	)	PUNCT
bjp-62725	60	20	and	and	CCONJ
bjp-62725	60	21	loading	loading	NOUN
bjp-62725	60	22	control	control	NOUN
bjp-62725	60	23	(	(	PUNCT
bjp-62725	60	24	gapdh	gapdh	NOUN
bjp-62725	60	25	)	)	PUNCT
bjp-62725	60	26	was	be	AUX
bjp-62725	60	27	quantified	quantify	VERB
bjp-62725	60	28	in	in	ADP
bjp-62725	60	29	chondrocytes	chondrocyte	NOUN
bjp-62725	60	30	treated	treat	VERB
bjp-62725	60	31	with	with	ADP
bjp-62725	60	32	colchicine	colchicine	PROPN
bjp-62725	60	33	in	in	ADP
bjp-62725	60	34	concentrationand	concentrationand	PROPN
bjp-62725	60	35	timedependent	timedependent	PROPN
bjp-62725	60	36	manner	manner	PROPN
bjp-62725	60	37	.	.	PUNCT
bjp-62725	61	1	western	western	ADJ
bjp-62725	61	2	blot	blot	NOUN
bjp-62725	61	3	analysis	analysis	NOUN
bjp-62725	61	4	indicated	indicate	VERB
bjp-62725	61	5	that	that	SCONJ
bjp-62725	61	6	colchicine	colchicine	NOUN
bjp-62725	61	7	-	-	PUNCT
bjp-62725	61	8	treated	treat	VERB
bjp-62725	61	9	cells	cell	NOUN
bjp-62725	61	10	induced	induce	VERB
bjp-62725	61	11	dedifferentiation	dedifferentiation	NOUN
bjp-62725	61	12	by	by	ADP
bjp-62725	61	13	decreasing	decrease	VERB
bjp-62725	61	14	the	the	DET
bjp-62725	61	15	expression	expression	NOUN
bjp-62725	61	16	of	of	ADP
bjp-62725	61	17	chondrocyte	chondrocyte	NOUN
bjp-62725	61	18	differentiation	differentiation	NOUN
bjp-62725	61	19	markers	marker	NOUN
bjp-62725	61	20	(	(	PUNCT
bjp-62725	61	21	type	type	NOUN
bjp-62725	61	22	ii	ii	PROPN
bjp-62725	61	23	collagen	collagen	NOUN
bjp-62725	61	24	,	,	PUNCT
bjp-62725	61	25	sox9	sox9	PROPN
bjp-62725	61	26	and	and	CCONJ
bjp-62725	61	27	aggrecans	aggrecan	NOUN
bjp-62725	61	28	)	)	PUNCT
bjp-62725	61	29	and	and	CCONJ
bjp-62725	61	30	disturbed	disturb	VERB
bjp-62725	61	31	the	the	DET
bjp-62725	61	32	microtubule	microtubule	NOUN
bjp-62725	61	33	polymerizing	polymerize	VERB
bjp-62725	61	34	monomers	monomer	NOUN
bjp-62725	61	35	(	(	PUNCT
bjp-62725	61	36	tubulin	tubulin	NOUN
bjp-62725	61	37	)	)	PUNCT
bjp-62725	61	38	in	in	ADP
bjp-62725	61	39	a	a	DET
bjp-62725	61	40	doseand	doseand	ADJ
bjp-62725	61	41	time	time	NOUN
bjp-62725	61	42	-	-	PUNCT
bjp-62725	61	43	dependently	dependently	ADV
bjp-62725	61	44	(	(	PUNCT
bjp-62725	61	45	figure	figure	NOUN
bjp-62725	61	46	1a	1a	NOUN
bjp-62725	61	47	,	,	PUNCT
bjp-62725	61	48	c	c	NOUN
bjp-62725	61	49	)	)	PUNCT
bjp-62725	61	50	.	.	PUNCT
bjp-62725	62	1	whereas	whereas	SCONJ
bjp-62725	62	2	,	,	PUNCT
bjp-62725	62	3	the	the	DET
bjp-62725	62	4	expression	expression	NOUN
bjp-62725	62	5	of	of	ADP
bjp-62725	62	6	cyclooxygenase-2	cyclooxygenase-2	NUM
bjp-62725	62	7	(	(	PUNCT
bjp-62725	62	8	cox-2	cox-2	NOUN
bjp-62725	62	9	)	)	PUNCT
bjp-62725	62	10	was	be	AUX
bjp-62725	62	11	also	also	ADV
bjp-62725	62	12	increased	increase	VERB
bjp-62725	62	13	.	.	PUNCT
bjp-62725	63	1	these	these	DET
bjp-62725	63	2	results	result	NOUN
bjp-62725	63	3	were	be	AUX
bjp-62725	63	4	further	far	ADV
bjp-62725	63	5	verified	verify	VERB
bjp-62725	63	6	with	with	ADP
bjp-62725	63	7	rtpcr	rtpcr	ADJ
bjp-62725	63	8	analysis	analysis	NOUN
bjp-62725	63	9	to	to	PART
bjp-62725	63	10	confirm	confirm	VERB
bjp-62725	63	11	the	the	DET
bjp-62725	63	12	relative	relative	ADJ
bjp-62725	63	13	gene	gene	NOUN
bjp-62725	63	14	-	-	PUNCT
bjp-62725	63	15	specific	specific	ADJ
bjp-62725	63	16	transcript	transcript	NOUN
bjp-62725	63	17	expression	expression	NOUN
bjp-62725	63	18	.	.	PUNCT
bjp-62725	64	1	the	the	DET
bjp-62725	64	2	rt	rt	ADJ
bjp-62725	64	3	-	-	PUNCT
bjp-62725	64	4	pcr	pcr	ADJ
bjp-62725	64	5	result	result	NOUN
bjp-62725	64	6	corroborated	corroborate	VERB
bjp-62725	64	7	the	the	DET
bjp-62725	64	8	findings	finding	NOUN
bjp-62725	64	9	of	of	ADP
bjp-62725	64	10	western	western	ADJ
bjp-62725	64	11	blot	blot	NOUN
bjp-62725	64	12	analysis	analysis	NOUN
bjp-62725	64	13	(	(	PUNCT
bjp-62725	64	14	figure	figure	NOUN
bjp-62725	64	15	1b	1b	NUM
bjp-62725	64	16	,	,	PUNCT
bjp-62725	64	17	d	d	NOUN
bjp-62725	64	18	)	)	PUNCT
bjp-62725	64	19	.	.	PUNCT
bjp-62725	65	1	the	the	DET
bjp-62725	65	2	quantitative	quantitative	ADJ
bjp-62725	65	3	findings	finding	NOUN
bjp-62725	65	4	procured	procure	VERB
bjp-62725	65	5	from	from	ADP
bjp-62725	65	6	alcian	alcian	PROPN
bjp-62725	65	7	blue	blue	ADJ
bjp-62725	65	8	staining	staining	NOUN
bjp-62725	65	9	indicated	indicate	VERB
bjp-62725	65	10	that	that	SCONJ
bjp-62725	65	11	colchicine	colchicine	PROPN
bjp-62725	65	12	halted	halt	VERB
bjp-62725	65	13	the	the	DET
bjp-62725	65	14	synthesis	synthesis	NOUN
bjp-62725	65	15	of	of	ADP
bjp-62725	65	16	sulfated	sulfate	VERB
bjp-62725	65	17	proteoglycans	proteoglycan	NOUN
bjp-62725	65	18	as	as	SCONJ
bjp-62725	65	19	shown	show	VERB
bjp-62725	65	20	in	in	ADP
bjp-62725	65	21	(	(	PUNCT
bjp-62725	65	22	figure	figure	NOUN
bjp-62725	65	23	1e	1e	NUM
bjp-62725	65	24	)	)	PUNCT
bjp-62725	65	25	.	.	PUNCT
bjp-62725	66	1	in	in	ADP
bjp-62725	66	2	the	the	DET
bjp-62725	66	3	following	follow	VERB
bjp-62725	66	4	experiment	experiment	NOUN
bjp-62725	66	5	,	,	PUNCT
bjp-62725	66	6	the	the	DET
bjp-62725	66	7	impact	impact	NOUN
bjp-62725	66	8	on	on	ADP
bjp-62725	66	9	microtubule	microtubule	NOUN
bjp-62725	66	10	polymerization	polymerization	NOUN
bjp-62725	66	11	and	and	CCONJ
bjp-62725	66	12	chondrocyte	chondrocyte	NOUN
bjp-62725	66	13	differentiation	differentiation	NOUN
bjp-62725	66	14	was	be	AUX
bjp-62725	66	15	investigated	investigate	VERB
bjp-62725	66	16	in	in	ADP
bjp-62725	66	17	colchicine	colchicine	NOUN
bjp-62725	66	18	-	-	PUNCT
bjp-62725	66	19	treated	treat	VERB
bjp-62725	66	20	cells	cell	NOUN
bjp-62725	66	21	.	.	PUNCT
bjp-62725	67	1	treatment	treatment	NOUN
bjp-62725	67	2	with	with	ADP
bjp-62725	67	3	colchicine	colchicine	PROPN
bjp-62725	67	4	reduced	reduce	VERB
bjp-62725	67	5	tubulin	tubulin	NOUN
bjp-62725	67	6	synthesis	synthesis	NOUN
bjp-62725	67	7	and	and	CCONJ
bjp-62725	67	8	differentiation	differentiation	NOUN
bjp-62725	67	9	of	of	ADP
bjp-62725	67	10	chondrocytes	chondrocyte	NOUN
bjp-62725	67	11	,	,	PUNCT
bjp-62725	67	12	as	as	SCONJ
bjp-62725	67	13	compared	compare	VERB
bjp-62725	67	14	to	to	ADP
bjp-62725	67	15	control	control	VERB
bjp-62725	67	16	,	,	PUNCT
bjp-62725	67	17	as	as	SCONJ
bjp-62725	67	18	demonstrated	demonstrate	VERB
bjp-62725	67	19	by	by	ADP
bjp-62725	67	20	immunofluorescence	immunofluorescence	NOUN
bjp-62725	67	21	staining	stain	VERB
bjp-62725	67	22	(	(	PUNCT
bjp-62725	67	23	figure	figure	NOUN
bjp-62725	67	24	2	2	NUM
bjp-62725	67	25	)	)	PUNCT
bjp-62725	67	26	.	.	PUNCT
bjp-62725	68	1	thus	thus	ADV
bjp-62725	68	2	,	,	PUNCT
bjp-62725	68	3	these	these	DET
bjp-62725	68	4	results	result	NOUN
bjp-62725	68	5	suggest	suggest	VERB
bjp-62725	68	6	that	that	SCONJ
bjp-62725	68	7	colchicine	colchicine	PROPN
bjp-62725	68	8	induces	induce	VERB
bjp-62725	68	9	chondrocyte	chondrocyte	PROPN
bjp-62725	68	10	dedifferentiation	dedifferentiation	NOUN
bjp-62725	68	11	and	and	CCONJ
bjp-62725	68	12	inflammation	inflammation	NOUN
bjp-62725	68	13	in	in	ADP
bjp-62725	68	14	primary	primary	ADJ
bjp-62725	68	15	chondrocytes	chondrocyte	NOUN
bjp-62725	68	16	.	.	PUNCT
bjp-62725	69	1	chondrocytes	chondrocyte	VERB
bjp-62725	69	2	dedifferentiation	dedifferentiation	NOUN
bjp-62725	69	3	via	via	ADP
bjp-62725	69	4	regulating	regulate	VERB
bjp-62725	69	5	microtubule	microtubule	NOUN
bjp-62725	69	6	polymerization	polymerization	NOUN
bjp-62725	69	7	to	to	PART
bjp-62725	69	8	prove	prove	VERB
bjp-62725	69	9	this	this	DET
bjp-62725	69	10	speculation	speculation	NOUN
bjp-62725	69	11	that	that	SCONJ
bjp-62725	69	12	colchicine	colchicine	PROPN
bjp-62725	69	13	influence	influence	NOUN
bjp-62725	69	14	on	on	ADP
bjp-62725	69	15	the	the	DET
bjp-62725	69	16	tubulin	tubulin	NOUN
bjp-62725	69	17	depolymerization	depolymerization	NOUN
bjp-62725	69	18	caused	cause	VERB
bjp-62725	69	19	the	the	DET
bjp-62725	69	20	chondrocyte	chondrocyte	PROPN
bjp-62725	69	21	dedifferentiation	dedifferentiation	NOUN
bjp-62725	69	22	paclitaxel	paclitaxel	PROPN
bjp-62725	69	23	was	be	AUX
bjp-62725	69	24	explored	explore	VERB
bjp-62725	69	25	which	which	PRON
bjp-62725	69	26	is	be	AUX
bjp-62725	69	27	a	a	DET
bjp-62725	69	28	microtubule	microtubule	NOUN
bjp-62725	69	29	polymerizing	polymerize	VERB
bjp-62725	69	30	agent	agent	NOUN
bjp-62725	69	31	and	and	CCONJ
bjp-62725	69	32	counteract	counteract	VERB
bjp-62725	69	33	their	their	PRON
bjp-62725	69	34	disassembly	disassembly	NOUN
bjp-62725	69	35	.	.	PUNCT
bjp-62725	70	1	the	the	DET
bjp-62725	70	2	influence	influence	NOUN
bjp-62725	70	3	of	of	ADP
bjp-62725	70	4	both	both	CCONJ
bjp-62725	70	5	paclitaxel	paclitaxel	PROPN
bjp-62725	70	6	and	and	CCONJ
bjp-62725	70	7	colchicine	colchicine	PROPN
bjp-62725	70	8	was	be	AUX
bjp-62725	70	9	analyzed	analyze	VERB
bjp-62725	70	10	with	with	ADP
bjp-62725	70	11	western	western	ADJ
bjp-62725	70	12	blotting	blotting	NOUN
bjp-62725	70	13	and	and	CCONJ
bjp-62725	70	14	immunofluorescence	immunofluorescence	NOUN
bjp-62725	70	15	and	and	CCONJ
bjp-62725	70	16	verified	verify	VERB
bjp-62725	70	17	with	with	ADP
bjp-62725	70	18	rt	rt	PROPN
bjp-62725	70	19	-	-	PUNCT
bjp-62725	70	20	pcr	pcr	ADJ
bjp-62725	70	21	and	and	CCONJ
bjp-62725	70	22	alcian	alcian	ADJ
bjp-62725	70	23	blue	blue	ADJ
bjp-62725	70	24	staining	stain	VERB
bjp-62725	70	25	.	.	PUNCT
bjp-62725	71	1	paclitaxel	paclitaxel	PROPN
bjp-62725	71	2	at	at	ADP
bjp-62725	71	3	a	a	DET
bjp-62725	71	4	concentration	concentration	NOUN
bjp-62725	71	5	of	of	ADP
bjp-62725	71	6	5	5	NUM
bjp-62725	71	7	µm	µm	NUM
bjp-62725	71	8	induced	induce	VERB
bjp-62725	71	9	chondrocyte	chondrocyte	NOUN
bjp-62725	71	10	differentiation	differentiation	NOUN
bjp-62725	71	11	and	and	CCONJ
bjp-62725	71	12	ameliorated	ameliorate	VERB
bjp-62725	71	13	expression	expression	NOUN
bjp-62725	71	14	of	of	ADP
bjp-62725	71	15	type	type	NOUN
bjp-62725	71	16	ii	ii	PROPN
bjp-62725	71	17	collagen	collagen	NOUN
bjp-62725	71	18	via	via	ADP
bjp-62725	71	19	mapk	mapk	NOUN
bjp-62725	71	20	pathway	pathway	NOUN
bjp-62725	71	21	(	(	PUNCT
bjp-62725	71	22	i	i	NOUN
bjp-62725	71	23	m	m	VERB
bjp-62725	71	24	and	and	CCONJ
bjp-62725	71	25	kim	kim	PROPN
bjp-62725	71	26	,	,	PUNCT
bjp-62725	71	27	2009	2009	NUM
bjp-62725	71	28	)	)	PUNCT
bjp-62725	71	29	.	.	PUNCT
bjp-62725	72	1	the	the	DET
bjp-62725	72	2	same	same	ADJ
bjp-62725	72	3	5	5	NUM
bjp-62725	72	4	µm	µm	NOUN
bjp-62725	72	5	concentration	concentration	NOUN
bjp-62725	72	6	was	be	AUX
bjp-62725	72	7	used	use	VERB
bjp-62725	72	8	for	for	ADP
bjp-62725	72	9	paclitaxel	paclitaxel	PROPN
bjp-62725	72	10	whereas	whereas	SCONJ
bjp-62725	72	11	1	1	NUM
bjp-62725	72	12	µm	µm	NOUN
bjp-62725	72	13	of	of	ADP
bjp-62725	72	14	colchicine	colchicine	NOUN
bjp-62725	72	15	and	and	CCONJ
bjp-62725	72	16	cotreated	cotreate	VERB
bjp-62725	72	17	together	together	ADV
bjp-62725	72	18	to	to	PART
bjp-62725	72	19	observe	observe	VERB
bjp-62725	72	20	the	the	DET
bjp-62725	72	21	effects	effect	NOUN
bjp-62725	72	22	on	on	ADP
bjp-62725	72	23	chondrocyte	chondrocyte	NOUN
bjp-62725	72	24	differentiation	differentiation	NOUN
bjp-62725	72	25	.	.	PUNCT
bjp-62725	73	1	exposure	exposure	NOUN
bjp-62725	73	2	to	to	ADP
bjp-62725	73	3	colchicine	colchicine	PROPN
bjp-62725	73	4	decreased	decrease	VERB
bjp-62725	73	5	the	the	DET
bjp-62725	73	6	chondrogenic	chondrogenic	ADJ
bjp-62725	73	7	markers	marker	NOUN
bjp-62725	73	8	(	(	PUNCT
bjp-62725	73	9	type	type	NOUN
bjp-62725	73	10	ii	ii	PROPN
bjp-62725	73	11	collagen	collagen	PROPN
bjp-62725	73	12	,	,	PUNCT
bjp-62725	73	13	sox9	sox9	PROPN
bjp-62725	73	14	,	,	PUNCT
bjp-62725	73	15	aggrecans	aggrecan	NOUN
bjp-62725	73	16	)	)	PUNCT
bjp-62725	73	17	and	and	CCONJ
bjp-62725	73	18	tubulin	tubulin	NOUN
bjp-62725	73	19	expression	expression	NOUN
bjp-62725	73	20	whereas	whereas	SCONJ
bjp-62725	73	21	paclitaxel	paclitaxel	PROPN
bjp-62725	73	22	increased	increase	VERB
bjp-62725	73	23	the	the	DET
bjp-62725	73	24	expression	expression	NOUN
bjp-62725	73	25	of	of	ADP
bjp-62725	73	26	tubulin	tubulin	NOUN
bjp-62725	73	27	and	and	CCONJ
bjp-62725	73	28	chondrogenic	chondrogenic	ADJ
bjp-62725	73	29	box	box	PROPN
bjp-62725	73	30	1	1	NUM
bjp-62725	73	31	:	:	PUNCT
bjp-62725	73	32	western	western	ADJ
bjp-62725	73	33	blotting	blotting	ADJ
bjp-62725	73	34	principle	principle	ADJ
bjp-62725	73	35	western	western	ADJ
bjp-62725	73	36	blotting	blotting	NOUN
bjp-62725	73	37	is	be	AUX
bjp-62725	73	38	based	base	VERB
bjp-62725	73	39	on	on	ADP
bjp-62725	73	40	the	the	DET
bjp-62725	73	41	principle	principle	NOUN
bjp-62725	73	42	of	of	ADP
bjp-62725	73	43	immunochromatography	immunochromatography	NOUN
bjp-62725	73	44	where	where	SCONJ
bjp-62725	73	45	proteins	protein	NOUN
bjp-62725	73	46	are	be	AUX
bjp-62725	73	47	separated	separate	VERB
bjp-62725	73	48	into	into	ADP
bjp-62725	73	49	polyacrylamide	polyacrylamide	ADJ
bjp-62725	73	50	gel	gel	NOUN
bjp-62725	73	51	according	accord	VERB
bjp-62725	73	52	to	to	ADP
bjp-62725	73	53	their	their	PRON
bjp-62725	73	54	molecular	molecular	ADJ
bjp-62725	73	55	weight	weight	NOUN
bjp-62725	73	56	.	.	PUNCT
bjp-62725	74	1	requirements	requirement	NOUN
bjp-62725	74	2	bca	bca	PROPN
bjp-62725	74	3	protein	protein	NOUN
bjp-62725	74	4	assay	assay	PROPN
bjp-62725	74	5	kit	kit	PROPN
bjp-62725	74	6	,	,	PUNCT
bjp-62725	74	7	cells	cell	NOUN
bjp-62725	74	8	pellet	pellet	NOUN
bjp-62725	74	9	,	,	PUNCT
bjp-62725	74	10	chemiluminescence	chemiluminescence	NOUN
bjp-62725	74	11	reagent	reagent	NOUN
bjp-62725	74	12	,	,	PUNCT
bjp-62725	74	13	chemiluminescence	chemiluminescence	NOUN
bjp-62725	74	14	detector	detector	NOUN
bjp-62725	74	15	,	,	PUNCT
bjp-62725	74	16	ripa	ripa	NOUN
bjp-62725	74	17	buffer	buffer	NOUN
bjp-62725	74	18	,	,	PUNCT
bjp-62725	74	19	protease	protease	NOUN
bjp-62725	74	20	cocktail	cocktail	NOUN
bjp-62725	74	21	,	,	PUNCT
bjp-62725	74	22	blocking	block	VERB
bjp-62725	74	23	buffer	buffer	NOUN
bjp-62725	74	24	,	,	PUNCT
bjp-62725	74	25	primary	primary	ADJ
bjp-62725	74	26	antibodies	antibody	NOUN
bjp-62725	74	27	,	,	PUNCT
bjp-62725	74	28	secondary	secondary	ADJ
bjp-62725	74	29	antibodies	antibody	NOUN
bjp-62725	74	30	,	,	PUNCT
bjp-62725	74	31	phosphate	phosphate	ADJ
bjp-62725	74	32	saline	saline	NOUN
bjp-62725	74	33	buffer	buffer	NOUN
bjp-62725	74	34	,	,	PUNCT
bjp-62725	74	35	1x	1x	NUM
bjp-62725	74	36	tris	tris	NOUN
bjp-62725	74	37	-	-	PUNCT
bjp-62725	74	38	buffered	buffer	VERB
bjp-62725	74	39	saline	saline	NOUN
bjp-62725	74	40	,	,	PUNCT
bjp-62725	74	41	0.1	0.1	NUM
bjp-62725	74	42	%	%	NOUN
bjp-62725	74	43	tween	tween	NOUN
bjp-62725	74	44	,	,	PUNCT
bjp-62725	74	45	sodium	sodium	NOUN
bjp-62725	74	46	polyacrylamide	polyacrylamide	NOUN
bjp-62725	74	47	gel	gel	NOUN
bjp-62725	74	48	,	,	PUNCT
bjp-62725	74	49	nitrocellulose	nitrocellulose	NOUN
bjp-62725	74	50	membrane	membrane	NOUN
bjp-62725	74	51	,	,	PUNCT
bjp-62725	74	52	transfer	transfer	NOUN
bjp-62725	74	53	buffer	buffer	NOUN
bjp-62725	74	54	procedure	procedure	NOUN
bjp-62725	74	55	step	step	NOUN
bjp-62725	74	56	1	1	NUM
bjp-62725	74	57	:	:	PUNCT
bjp-62725	74	58	rabbit	rabbit	NOUN
bjp-62725	74	59	articular	articular	ADJ
bjp-62725	74	60	chondrocytes	chondrocyte	NOUN
bjp-62725	74	61	were	be	AUX
bjp-62725	74	62	treated	treat	VERB
bjp-62725	74	63	with	with	ADP
bjp-62725	74	64	colchicine	colchicine	NOUN
bjp-62725	74	65	and	and	CCONJ
bjp-62725	74	66	incubated	incubate	VERB
bjp-62725	74	67	for	for	ADP
bjp-62725	74	68	24	24	NUM
bjp-62725	74	69	hours	hour	NOUN
bjp-62725	74	70	at	at	ADP
bjp-62725	74	71	37ºc	37ºc	NOUN
bjp-62725	74	72	with	with	ADP
bjp-62725	74	73	5	5	NUM
bjp-62725	74	74	%	%	NOUN
bjp-62725	74	75	carbon	carbon	NOUN
bjp-62725	74	76	dioxide	dioxide	NOUN
bjp-62725	74	77	incubator	incubator	NOUN
bjp-62725	74	78	step	step	NOUN
bjp-62725	74	79	2	2	NUM
bjp-62725	74	80	:	:	PUNCT
bjp-62725	74	81	after	after	ADP
bjp-62725	74	82	incubation	incubation	NOUN
bjp-62725	74	83	,	,	PUNCT
bjp-62725	74	84	cells	cell	NOUN
bjp-62725	74	85	media	medium	NOUN
bjp-62725	74	86	was	be	AUX
bjp-62725	74	87	removed	remove	VERB
bjp-62725	74	88	and	and	CCONJ
bjp-62725	74	89	phosphate	phosphate	ADJ
bjp-62725	74	90	buffer	buffer	NOUN
bjp-62725	74	91	was	be	AUX
bjp-62725	74	92	added	add	VERB
bjp-62725	74	93	and	and	CCONJ
bjp-62725	74	94	then	then	ADV
bjp-62725	74	95	cells	cell	NOUN
bjp-62725	74	96	were	be	AUX
bjp-62725	74	97	scrapped	scrap	VERB
bjp-62725	74	98	from	from	ADP
bjp-62725	74	99	the	the	DET
bjp-62725	74	100	cell	cell	NOUN
bjp-62725	74	101	culturing	culture	VERB
bjp-62725	74	102	dish	dish	NOUN
bjp-62725	74	103	and	and	CCONJ
bjp-62725	74	104	centrifuged	centrifuge	VERB
bjp-62725	74	105	at	at	ADP
bjp-62725	74	106	13,000	13,000	NUM
bjp-62725	74	107	rpm	rpm	NOUN
bjp-62725	74	108	for	for	ADP
bjp-62725	74	109	10	10	NUM
bjp-62725	74	110	min	min	NOUN
bjp-62725	74	111	at	at	ADP
bjp-62725	74	112	4ºc	4ºc	ADJ
bjp-62725	74	113	step	step	NOUN
bjp-62725	74	114	3	3	NUM
bjp-62725	74	115	:	:	PUNCT
bjp-62725	74	116	phosphate	phosphate	ADJ
bjp-62725	74	117	buffer	buffer	NOUN
bjp-62725	74	118	was	be	AUX
bjp-62725	74	119	then	then	ADV
bjp-62725	74	120	removed	remove	VERB
bjp-62725	74	121	and	and	CCONJ
bjp-62725	74	122	ripa	ripa	ADJ
bjp-62725	74	123	buffer	buffer	NOUN
bjp-62725	74	124	containing	contain	VERB
bjp-62725	74	125	protease	protease	NOUN
bjp-62725	74	126	cocktail	cocktail	NOUN
bjp-62725	74	127	was	be	AUX
bjp-62725	74	128	added	add	VERB
bjp-62725	74	129	on	on	ADP
bjp-62725	74	130	to	to	ADP
bjp-62725	74	131	the	the	DET
bjp-62725	74	132	pellets	pellet	NOUN
bjp-62725	74	133	to	to	PART
bjp-62725	74	134	extract	extract	VERB
bjp-62725	74	135	the	the	DET
bjp-62725	74	136	proteins	protein	NOUN
bjp-62725	74	137	by	by	ADP
bjp-62725	74	138	inducing	induce	VERB
bjp-62725	74	139	cell	cell	NOUN
bjp-62725	74	140	lysis	lysis	NOUN
bjp-62725	74	141	step	step	NOUN
bjp-62725	74	142	4	4	NUM
bjp-62725	74	143	:	:	PUNCT
bjp-62725	74	144	protein	protein	NOUN
bjp-62725	74	145	concentration	concentration	NOUN
bjp-62725	74	146	obtained	obtain	VERB
bjp-62725	74	147	from	from	ADP
bjp-62725	74	148	cell	cell	NOUN
bjp-62725	74	149	lysis	lysis	NOUN
bjp-62725	74	150	was	be	AUX
bjp-62725	74	151	then	then	ADV
bjp-62725	74	152	quantified	quantify	VERB
bjp-62725	74	153	with	with	ADP
bjp-62725	74	154	bca	bca	PROPN
bjp-62725	74	155	protein	protein	NOUN
bjp-62725	74	156	assay	assay	NOUN
bjp-62725	74	157	kit	kit	NOUN
bjp-62725	74	158	step	step	NOUN
bjp-62725	74	159	5	5	NUM
bjp-62725	74	160	:	:	PUNCT
bjp-62725	74	161	quantified	quantify	VERB
bjp-62725	74	162	proteins	protein	NOUN
bjp-62725	74	163	were	be	AUX
bjp-62725	74	164	then	then	ADV
bjp-62725	74	165	added	add	VERB
bjp-62725	74	166	to	to	ADP
bjp-62725	74	167	the	the	DET
bjp-62725	74	168	9	9	NUM
bjp-62725	74	169	%	%	NOUN
bjp-62725	74	170	polyacrylamide	polyacrylamide	NOUN
bjp-62725	74	171	gel	gel	NOUN
bjp-62725	74	172	to	to	PART
bjp-62725	74	173	separate	separate	VERB
bjp-62725	74	174	the	the	DET
bjp-62725	74	175	proteins	protein	NOUN
bjp-62725	74	176	according	accord	VERB
bjp-62725	74	177	to	to	ADP
bjp-62725	74	178	their	their	PRON
bjp-62725	74	179	molecular	molecular	ADJ
bjp-62725	74	180	weight	weight	NOUN
bjp-62725	74	181	step	step	NOUN
bjp-62725	74	182	6	6	NUM
bjp-62725	74	183	:	:	PUNCT
bjp-62725	74	184	step	step	NOUN
bjp-62725	74	185	6	6	NUM
bjp-62725	74	186	.	.	PUNCT
bjp-62725	75	1	separated	separate	VERB
bjp-62725	75	2	protein	protein	NOUN
bjp-62725	75	3	gel	gel	NOUN
bjp-62725	75	4	was	be	AUX
bjp-62725	75	5	then	then	ADV
bjp-62725	75	6	transferred	transfer	VERB
bjp-62725	75	7	to	to	ADP
bjp-62725	75	8	the	the	DET
bjp-62725	75	9	nitrocellulose	nitrocellulose	NOUN
bjp-62725	75	10	membrane	membrane	NOUN
bjp-62725	75	11	with	with	ADP
bjp-62725	75	12	the	the	DET
bjp-62725	75	13	aid	aid	NOUN
bjp-62725	75	14	of	of	ADP
bjp-62725	75	15	transfer	transfer	NOUN
bjp-62725	75	16	buffer	buffer	NOUN
bjp-62725	75	17	step	step	NOUN
bjp-62725	75	18	7	7	NUM
bjp-62725	75	19	:	:	PUNCT
bjp-62725	75	20	nitrocellulose	nitrocellulose	NOUN
bjp-62725	75	21	containing	contain	VERB
bjp-62725	75	22	protein	protein	NOUN
bjp-62725	75	23	bands	band	NOUN
bjp-62725	75	24	were	be	AUX
bjp-62725	75	25	cleaved	cleave	VERB
bjp-62725	75	26	according	accord	VERB
bjp-62725	75	27	to	to	ADP
bjp-62725	75	28	the	the	DET
bjp-62725	75	29	specific	specific	ADJ
bjp-62725	75	30	protein	protein	NOUN
bjp-62725	75	31	markers	marker	NOUN
bjp-62725	75	32	step	step	VERB
bjp-62725	75	33	8	8	NUM
bjp-62725	75	34	:	:	PUNCT
bjp-62725	75	35	cleaved	cleaved	ADJ
bjp-62725	75	36	protein	protein	NOUN
bjp-62725	75	37	bands	band	NOUN
bjp-62725	75	38	were	be	AUX
bjp-62725	75	39	then	then	ADV
bjp-62725	75	40	washed	wash	VERB
bjp-62725	75	41	thrice	thrice	NOUN
bjp-62725	75	42	with	with	ADP
bjp-62725	75	43	tbst	tbst	PROPN
bjp-62725	75	44	and	and	CCONJ
bjp-62725	75	45	then	then	ADV
bjp-62725	75	46	blocked	block	VERB
bjp-62725	75	47	with	with	ADP
bjp-62725	75	48	blocking	block	VERB
bjp-62725	75	49	buffer	buffer	NOUN
bjp-62725	75	50	for	for	ADP
bjp-62725	75	51	1	1	NUM
bjp-62725	75	52	hour	hour	NOUN
bjp-62725	75	53	at	at	ADP
bjp-62725	75	54	room	room	NOUN
bjp-62725	75	55	temperature	temperature	NOUN
bjp-62725	75	56	step	step	NOUN
bjp-62725	75	57	9	9	NUM
bjp-62725	75	58	:	:	PUNCT
bjp-62725	75	59	after	after	ADP
bjp-62725	75	60	blocking	block	VERB
bjp-62725	75	61	,	,	PUNCT
bjp-62725	75	62	bands	band	NOUN
bjp-62725	75	63	were	be	AUX
bjp-62725	75	64	washed	wash	VERB
bjp-62725	75	65	again	again	ADV
bjp-62725	75	66	with	with	ADP
bjp-62725	75	67	tbst	tbst	PROPN
bjp-62725	75	68	and	and	CCONJ
bjp-62725	75	69	then	then	ADV
bjp-62725	75	70	added	add	VERB
bjp-62725	75	71	to	to	ADP
bjp-62725	75	72	the	the	DET
bjp-62725	75	73	primary	primary	ADJ
bjp-62725	75	74	antibody	antibody	NOUN
bjp-62725	75	75	on	on	ADP
bjp-62725	75	76	a	a	DET
bjp-62725	75	77	shaker	shaker	NOUN
bjp-62725	75	78	incubator	incubator	NOUN
bjp-62725	75	79	at	at	ADP
bjp-62725	75	80	4ºc	4ºc	ADJ
bjp-62725	75	81	overnight	overnight	ADJ
bjp-62725	75	82	step	step	NOUN
bjp-62725	75	83	10	10	NUM
bjp-62725	75	84	:	:	PUNCT
bjp-62725	75	85	the	the	DET
bjp-62725	75	86	protein	protein	NOUN
bjp-62725	75	87	bands	band	NOUN
bjp-62725	75	88	were	be	AUX
bjp-62725	75	89	then	then	ADV
bjp-62725	75	90	taken	take	VERB
bjp-62725	75	91	out	out	ADP
bjp-62725	75	92	of	of	ADP
bjp-62725	75	93	primary	primary	ADJ
bjp-62725	75	94	antibody	antibody	NOUN
bjp-62725	75	95	and	and	CCONJ
bjp-62725	75	96	washed	wash	VERB
bjp-62725	75	97	thrice	thrice	NOUN
bjp-62725	75	98	with	with	ADP
bjp-62725	75	99	tbst	tbst	PROPN
bjp-62725	75	100	and	and	CCONJ
bjp-62725	75	101	then	then	ADV
bjp-62725	75	102	added	add	VERB
bjp-62725	75	103	on	on	ADP
bjp-62725	75	104	to	to	ADP
bjp-62725	75	105	the	the	DET
bjp-62725	75	106	secondary	secondary	ADJ
bjp-62725	75	107	antibody	antibody	NOUN
bjp-62725	75	108	step	step	NOUN
bjp-62725	75	109	11	11	NUM
bjp-62725	75	110	:	:	PUNCT
bjp-62725	75	111	after	after	ADP
bjp-62725	75	112	exposure	exposure	NOUN
bjp-62725	75	113	to	to	ADP
bjp-62725	75	114	secondary	secondary	ADJ
bjp-62725	75	115	antibody	antibody	NOUN
bjp-62725	75	116	,	,	PUNCT
bjp-62725	75	117	the	the	DET
bjp-62725	75	118	protein	protein	NOUN
bjp-62725	75	119	bands	band	NOUN
bjp-62725	75	120	were	be	AUX
bjp-62725	75	121	washed	wash	VERB
bjp-62725	75	122	again	again	ADV
bjp-62725	75	123	with	with	ADP
bjp-62725	75	124	tbst	tbst	PROPN
bjp-62725	75	125	and	and	CCONJ
bjp-62725	75	126	then	then	ADV
bjp-62725	75	127	visualized	visualize	VERB
bjp-62725	75	128	with	with	ADP
bjp-62725	75	129	chemiluminescence	chemiluminescence	NOUN
bjp-62725	75	130	solution	solution	NOUN
bjp-62725	75	131	using	use	VERB
bjp-62725	75	132	autoradiography	autoradiography	NOUN
bjp-62725	75	133	detector	detector	NOUN
bjp-62725	75	134	reference	reference	NOUN
bjp-62725	75	135	han	han	PROPN
bjp-62725	75	136	et	et	PROPN
bjp-62725	75	137	al	al	PROPN
bjp-62725	75	138	.	.	PROPN
bjp-62725	75	139	,	,	PUNCT
bjp-62725	75	140	2022	2022	NUM
bjp-62725	75	141	references	reference	NOUN
bjp-62725	75	142	(	(	PUNCT
bjp-62725	75	143	video	video	NOUN
bjp-62725	75	144	)	)	PUNCT
bjp-62725	75	145	eslami	eslami	NOUN
bjp-62725	75	146	and	and	CCONJ
bjp-62725	75	147	lujan	lujan	PROPN
bjp-62725	75	148	,	,	PUNCT
bjp-62725	75	149	2010	2010	NUM
bjp-62725	75	150	;	;	PUNCT
bjp-62725	75	151	shen	shen	PROPN
bjp-62725	75	152	et	et	PROPN
bjp-62725	75	153	al	al	PROPN
bjp-62725	75	154	.	.	PROPN
bjp-62725	75	155	,	,	PUNCT
bjp-62725	75	156	2021	2021	NUM
bjp-62725	75	157	;	;	PUNCT
bjp-62725	75	158	lim	lim	PROPN
bjp-62725	75	159	et	et	PROPN
bjp-62725	75	160	al	al	PROPN
bjp-62725	75	161	.	.	PROPN
bjp-62725	75	162	,	,	PUNCT
bjp-62725	75	163	2021	2021	NUM
bjp-62725	75	164	;	;	PUNCT
bjp-62725	75	165	liu	liu	PROPN
bjp-62725	75	166	et	et	PROPN
bjp-62725	75	167	al	al	PROPN
bjp-62725	75	168	.	.	PROPN
bjp-62725	75	169	,	,	PUNCT
bjp-62725	75	170	2021	2021	NUM
bjp-62725	75	171	10	10	NUM
bjp-62725	75	172	bangladesh	bangladesh	PROPN
bjp-62725	75	173	j	j	PROPN
bjp-62725	75	174	pharmacol	pharmacol	PROPN
bjp-62725	75	175	2023	2023	NUM
bjp-62725	75	176	;	;	PUNCT
bjp-62725	75	177	18	18	NUM
bjp-62725	75	178	:	:	SYM
bjp-62725	75	179	8	8	NUM
bjp-62725	75	180	-	-	SYM
bjp-62725	75	181	16	16	NUM
bjp-62725	75	182	markers	marker	NOUN
bjp-62725	75	183	(	(	PUNCT
bjp-62725	75	184	figure	figure	NOUN
bjp-62725	75	185	3a	3a	NUM
bjp-62725	75	186	)	)	PUNCT
bjp-62725	75	187	.	.	PUNCT
bjp-62725	76	1	but	but	CCONJ
bjp-62725	76	2	when	when	SCONJ
bjp-62725	76	3	both	both	PRON
bjp-62725	76	4	these	these	DET
bjp-62725	76	5	drugs	drug	NOUN
bjp-62725	76	6	cotreated	cotreate	VERB
bjp-62725	76	7	together	together	ADV
bjp-62725	76	8	in	in	ADP
bjp-62725	76	9	chondrocyte	chondrocyte	PROPN
bjp-62725	76	10	,	,	PUNCT
bjp-62725	76	11	paclitaxel	paclitaxel	PROPN
bjp-62725	76	12	counteracted	counteract	VERB
bjp-62725	76	13	the	the	DET
bjp-62725	76	14	effect	effect	NOUN
bjp-62725	76	15	of	of	ADP
bjp-62725	76	16	colchicine	colchicine	NOUN
bjp-62725	76	17	by	by	ADP
bjp-62725	76	18	rescuing	rescue	VERB
bjp-62725	76	19	the	the	DET
bjp-62725	76	20	chondrogenic	chondrogenic	ADJ
bjp-62725	76	21	and	and	CCONJ
bjp-62725	76	22	tubulin	tubulin	NOUN
bjp-62725	76	23	expression	expression	NOUN
bjp-62725	76	24	as	as	SCONJ
bjp-62725	76	25	confirmed	confirm	VERB
bjp-62725	76	26	with	with	ADP
bjp-62725	76	27	rt	rt	ADJ
bjp-62725	76	28	-	-	PUNCT
bjp-62725	76	29	pcr	pcr	NOUN
bjp-62725	76	30	analysis	analysis	NOUN
bjp-62725	76	31	(	(	PUNCT
bjp-62725	76	32	figure	figure	NOUN
bjp-62725	76	33	3b	3b	NUM
bjp-62725	76	34	)	)	PUNCT
bjp-62725	76	35	.	.	PUNCT
bjp-62725	77	1	the	the	DET
bjp-62725	77	2	changes	change	NOUN
bjp-62725	77	3	in	in	ADP
bjp-62725	77	4	polymerization	polymerization	NOUN
bjp-62725	77	5	and	and	CCONJ
bjp-62725	77	6	depolymerization	depolymerization	NOUN
bjp-62725	77	7	of	of	ADP
bjp-62725	77	8	microtubules	microtubule	NOUN
bjp-62725	77	9	in	in	ADP
bjp-62725	77	10	treated	treat	VERB
bjp-62725	77	11	chondrocytes	chondrocyte	NOUN
bjp-62725	77	12	were	be	AUX
bjp-62725	77	13	observed	observe	VERB
bjp-62725	77	14	via	via	ADP
bjp-62725	77	15	immunofluorescence	immunofluorescence	NOUN
bjp-62725	77	16	staining	stain	VERB
bjp-62725	77	17	(	(	PUNCT
bjp-62725	77	18	figure	figure	NOUN
bjp-62725	77	19	3c	3c	NUM
bjp-62725	77	20	)	)	PUNCT
bjp-62725	77	21	.	.	PUNCT
bjp-62725	78	1	treatment	treatment	NOUN
bjp-62725	78	2	with	with	ADP
bjp-62725	78	3	paclitaxel	paclitaxel	PROPN
bjp-62725	78	4	increased	increase	VERB
bjp-62725	78	5	the	the	DET
bjp-62725	78	6	differentiation	differentiation	NOUN
bjp-62725	78	7	of	of	ADP
bjp-62725	78	8	chondrocytes	chondrocyte	NOUN
bjp-62725	78	9	and	and	CCONJ
bjp-62725	78	10	tubulin	tubulin	NOUN
bjp-62725	78	11	expression	expression	NOUN
bjp-62725	78	12	,	,	PUNCT
bjp-62725	78	13	and	and	CCONJ
bjp-62725	78	14	also	also	ADV
bjp-62725	78	15	increased	increase	VERB
bjp-62725	78	16	colchicine	colchicine	NOUN
bjp-62725	78	17	-	-	PUNCT
bjp-62725	78	18	reduced	reduce	VERB
bjp-62725	78	19	expression	expression	NOUN
bjp-62725	78	20	of	of	ADP
bjp-62725	78	21	type	type	NOUN
bjp-62725	78	22	ii	ii	PROPN
bjp-62725	78	23	collagen	collagen	NOUN
bjp-62725	78	24	(	(	PUNCT
bjp-62725	78	25	figure	figure	NOUN
bjp-62725	78	26	2c	2c	NUM
bjp-62725	78	27	)	)	PUNCT
bjp-62725	78	28	.	.	PUNCT
bjp-62725	79	1	staining	stain	VERB
bjp-62725	79	2	results	result	NOUN
bjp-62725	79	3	also	also	ADV
bjp-62725	79	4	support	support	VERB
bjp-62725	79	5	the	the	DET
bjp-62725	79	6	mechanism	mechanism	NOUN
bjp-62725	79	7	of	of	ADP
bjp-62725	79	8	regulation	regulation	NOUN
bjp-62725	79	9	of	of	ADP
bjp-62725	79	10	microtubule	microtubule	NOUN
bjp-62725	79	11	synthesis	synthesis	NOUN
bjp-62725	79	12	in	in	ADP
bjp-62725	79	13	chondrocyte	chondrocyte	NOUN
bjp-62725	79	14	differentiation	differentiation	NOUN
bjp-62725	79	15	(	(	PUNCT
bjp-62725	79	16	figure	figure	NOUN
bjp-62725	79	17	3d	3d	NUM
bjp-62725	79	18	)	)	PUNCT
bjp-62725	79	19	.	.	PUNCT
bjp-62725	80	1	these	these	DET
bjp-62725	80	2	results	result	NOUN
bjp-62725	80	3	suggest	suggest	VERB
bjp-62725	80	4	that	that	SCONJ
bjp-62725	80	5	colchicine	colchicine	PROPN
bjp-62725	80	6	treatment	treatment	NOUN
bjp-62725	80	7	halts	halt	VERB
bjp-62725	80	8	tubulin	tubulin	NOUN
bjp-62725	80	9	synthesis	synthesis	NOUN
bjp-62725	80	10	in	in	ADP
bjp-62725	80	11	chondrocytes	chondrocyte	NOUN
bjp-62725	80	12	and	and	CCONJ
bjp-62725	80	13	thereby	thereby	ADV
bjp-62725	80	14	disrupts	disrupt	VERB
bjp-62725	80	15	the	the	DET
bjp-62725	80	16	chondrocyte	chondrocyte	NOUN
bjp-62725	80	17	differentiation	differentiation	NOUN
bjp-62725	80	18	process	process	NOUN
bjp-62725	80	19	(	(	PUNCT
bjp-62725	80	20	figure	figure	NOUN
bjp-62725	80	21	3	3	NUM
bjp-62725	80	22	)	)	PUNCT
bjp-62725	80	23	.	.	PUNCT
bjp-62725	81	1	expression	expression	NOUN
bjp-62725	81	2	of	of	ADP
bjp-62725	81	3	β	β	NOUN
bjp-62725	81	4	-	-	ADJ
bjp-62725	81	5	catenin	catenin	NOUN
bjp-62725	81	6	and	and	CCONJ
bjp-62725	81	7	iκbα	iκbα	ADV
bjp-62725	81	8	the	the	DET
bjp-62725	81	9	experiments	experiment	NOUN
bjp-62725	81	10	showed	show	VERB
bjp-62725	81	11	that	that	SCONJ
bjp-62725	81	12	colchicine	colchicine	PROPN
bjp-62725	81	13	inflicted	inflict	VERB
bjp-62725	81	14	dedifferentiation	dedifferentiation	NOUN
bjp-62725	81	15	in	in	ADP
bjp-62725	81	16	the	the	DET
bjp-62725	81	17	chondrocytes	chondrocyte	NOUN
bjp-62725	81	18	and	and	CCONJ
bjp-62725	81	19	increased	increase	VERB
bjp-62725	81	20	the	the	DET
bjp-62725	81	21	expression	expression	NOUN
bjp-62725	81	22	of	of	ADP
bjp-62725	81	23	cox-2	cox-2	NUM
bjp-62725	81	24	which	which	PRON
bjp-62725	81	25	made	make	VERB
bjp-62725	81	26	us	we	PRON
bjp-62725	81	27	explore	explore	VERB
bjp-62725	81	28	the	the	DET
bjp-62725	81	29	expression	expression	NOUN
bjp-62725	81	30	of	of	ADP
bjp-62725	81	31	β	β	NOUN
bjp-62725	81	32	-	-	ADJ
bjp-62725	81	33	catenin	catenin	NOUN
bjp-62725	81	34	and	and	CCONJ
bjp-62725	81	35	iκbα	iκbα	ADV
bjp-62725	81	36	in	in	ADP
bjp-62725	81	37	the	the	DET
bjp-62725	81	38	treated	treat	VERB
bjp-62725	81	39	cells	cell	NOUN
bjp-62725	81	40	.	.	PUNCT
bjp-62725	82	1	the	the	DET
bjp-62725	82	2	results	result	NOUN
bjp-62725	82	3	indicated	indicate	VERB
bjp-62725	82	4	that	that	SCONJ
bjp-62725	82	5	in	in	ADP
bjp-62725	82	6	concentration	concentration	NOUN
bjp-62725	82	7	dependent	dependent	ADJ
bjp-62725	82	8	manner	manner	NOUN
bjp-62725	82	9	,	,	PUNCT
bjp-62725	82	10	colchicine	colchicine	PROPN
bjp-62725	82	11	ameliorated	ameliorate	VERB
bjp-62725	82	12	the	the	DET
bjp-62725	82	13	expression	expression	NOUN
bjp-62725	82	14	of	of	ADP
bjp-62725	82	15	βcatenin	βcatenin	PROPN
bjp-62725	82	16	via	via	ADP
bjp-62725	82	17	phosphorylation	phosphorylation	NOUN
bjp-62725	82	18	of	of	ADP
bjp-62725	82	19	gsk-3αβ	gsk-3αβ	NOUN
bjp-62725	82	20	(	(	PUNCT
bjp-62725	82	21	figure	figure	NOUN
bjp-62725	82	22	4a	4a	NUM
bjp-62725	82	23	)	)	PUNCT
bjp-62725	82	24	.	.	PUNCT
bjp-62725	83	1	the	the	DET
bjp-62725	83	2	mechanism	mechanism	NOUN
bjp-62725	83	3	of	of	ADP
bjp-62725	83	4	colchicine	colchicine	NOUN
bjp-62725	83	5	-	-	PUNCT
bjp-62725	83	6	induced	induce	VERB
bjp-62725	83	7	inflammatory	inflammatory	ADJ
bjp-62725	83	8	reaction	reaction	NOUN
bjp-62725	83	9	was	be	AUX
bjp-62725	83	10	confirmed	confirm	VERB
bjp-62725	83	11	by	by	ADP
bjp-62725	83	12	treatment	treatment	NOUN
bjp-62725	83	13	with	with	ADP
bjp-62725	83	14	bms	bms	PROPN
bjp-62725	83	15	345541	345541	NUM
bjp-62725	83	16	,	,	PUNCT
bjp-62725	83	17	a	a	DET
bjp-62725	83	18	highly	highly	ADV
bjp-62725	83	19	selective	selective	ADJ
bjp-62725	83	20	ikkα	ikkα	NOUN
bjp-62725	83	21	inhibitor	inhibitor	NOUN
bjp-62725	83	22	(	(	PUNCT
bjp-62725	83	23	figure	figure	VERB
bjp-62725	83	24	6a	6a	NOUN
bjp-62725	83	25	)	)	PUNCT
bjp-62725	83	26	.	.	PUNCT
bjp-62725	84	1	it	it	PRON
bjp-62725	84	2	was	be	AUX
bjp-62725	84	3	confirmed	confirm	VERB
bjp-62725	84	4	with	with	ADP
bjp-62725	84	5	western	western	ADJ
bjp-62725	84	6	blot	blot	NOUN
bjp-62725	84	7	that	that	PRON
bjp-62725	84	8	bms	bms	PROPN
bjp-62725	84	9	345541	345541	NUM
bjp-62725	84	10	not	not	PART
bjp-62725	84	11	only	only	ADV
bjp-62725	84	12	c	c	PROPN
bjp-62725	84	13	b	b	PROPN
bjp-62725	84	14	a	a	DET
bjp-62725	84	15	d	d	NOUN
bjp-62725	84	16	figure	figure	NOUN
bjp-62725	84	17	1	1	NUM
bjp-62725	84	18	:	:	PUNCT
bjp-62725	84	19	colchicine	colchicine	NOUN
bjp-62725	84	20	reduces	reduce	VERB
bjp-62725	84	21	tubulin	tubulin	NOUN
bjp-62725	84	22	synthesis	synthesis	NOUN
bjp-62725	84	23	and	and	CCONJ
bjp-62725	84	24	chondrocytes	chondrocyte	VERB
bjp-62725	84	25	differentiation	differentiation	NOUN
bjp-62725	84	26	and	and	CCONJ
bjp-62725	84	27	induces	induce	VERB
bjp-62725	84	28	cox-2	cox-2	DET
bjp-62725	84	29	expression	expression	NOUN
bjp-62725	84	30	in	in	ADP
bjp-62725	84	31	articular	articular	ADJ
bjp-62725	84	32	chondrocytes	chondrocyte	NOUN
bjp-62725	84	33	chondrocytes	chondrocyte	NOUN
bjp-62725	84	34	were	be	AUX
bjp-62725	84	35	either	either	CCONJ
bjp-62725	84	36	left	leave	VERB
bjp-62725	84	37	untreated	untreated	ADJ
bjp-62725	84	38	or	or	CCONJ
bjp-62725	84	39	given	give	VERB
bjp-62725	84	40	different	different	ADJ
bjp-62725	84	41	doses	dose	NOUN
bjp-62725	84	42	of	of	ADP
bjp-62725	84	43	colchicine	colchicine	NOUN
bjp-62725	84	44	for	for	ADP
bjp-62725	84	45	24	24	NUM
bjp-62725	84	46	hours	hour	NOUN
bjp-62725	84	47	in	in	ADP
bjp-62725	84	48	(	(	PUNCT
bjp-62725	84	49	a	a	PRON
bjp-62725	84	50	and	and	CCONJ
bjp-62725	84	51	b	b	NOUN
bjp-62725	84	52	)	)	PUNCT
bjp-62725	84	53	.	.	PUNCT
bjp-62725	85	1	by	by	ADP
bjp-62725	85	2	using	use	VERB
bjp-62725	85	3	western	western	ADJ
bjp-62725	85	4	blot	blot	NOUN
bjp-62725	85	5	(	(	PUNCT
bjp-62725	85	6	a	a	NOUN
bjp-62725	85	7	)	)	PUNCT
bjp-62725	85	8	or	or	CCONJ
bjp-62725	85	9	rt	rt	NOUN
bjp-62725	85	10	-	-	PUNCT
bjp-62725	85	11	pcr	pcr	NOUN
bjp-62725	85	12	,	,	PUNCT
bjp-62725	85	13	the	the	DET
bjp-62725	85	14	expression	expression	NOUN
bjp-62725	85	15	levels	level	NOUN
bjp-62725	85	16	of	of	ADP
bjp-62725	85	17	tubulin	tubulin	NOUN
bjp-62725	85	18	,	,	PUNCT
bjp-62725	85	19	type	type	NOUN
bjp-62725	85	20	ii	ii	PROPN
bjp-62725	85	21	collagen	collagen	NOUN
bjp-62725	85	22	,	,	PUNCT
bjp-62725	85	23	aggrecan	aggrecan	ADJ
bjp-62725	85	24	,	,	PUNCT
bjp-62725	85	25	sox-9	sox-9	PRON
bjp-62725	85	26	,	,	PUNCT
bjp-62725	85	27	cox-2	cox-2	NOUN
bjp-62725	85	28	,	,	PUNCT
bjp-62725	85	29	and	and	CCONJ
bjp-62725	85	30	glyceraldehyde-3	glyceraldehyde-3	VERB
bjp-62725	85	31	-	-	ADJ
bjp-62725	85	32	phosphate	phosphate	ADJ
bjp-62725	85	33	dehydrogenase	dehydrogenase	NOUN
bjp-62725	85	34	(	(	PUNCT
bjp-62725	85	35	gapdh	gapdh	NOUN
bjp-62725	85	36	)	)	PUNCT
bjp-62725	85	37	were	be	AUX
bjp-62725	85	38	examined	examine	VERB
bjp-62725	85	39	(	(	PUNCT
bjp-62725	85	40	b	b	NOUN
bjp-62725	85	41	)	)	PUNCT
bjp-62725	85	42	.	.	PUNCT
bjp-62725	86	1	gapdh	gapdh	NOUN
bjp-62725	86	2	was	be	AUX
bjp-62725	86	3	used	use	VERB
bjp-62725	86	4	as	as	ADP
bjp-62725	86	5	a	a	DET
bjp-62725	86	6	loading	loading	NOUN
bjp-62725	86	7	control	control	NOUN
bjp-62725	86	8	.	.	PUNCT
bjp-62725	87	1	(	(	PUNCT
bjp-62725	87	2	c	c	NOUN
bjp-62725	87	3	and	and	CCONJ
bjp-62725	87	4	d	d	NOUN
bjp-62725	87	5	)	)	PUNCT
bjp-62725	87	6	for	for	ADP
bjp-62725	87	7	24	24	NUM
bjp-62725	87	8	hours	hour	NOUN
bjp-62725	87	9	,	,	PUNCT
bjp-62725	87	10	chondrocytes	chondrocyte	NOUN
bjp-62725	87	11	were	be	AUX
bjp-62725	87	12	either	either	CCONJ
bjp-62725	87	13	left	leave	VERB
bjp-62725	87	14	untreated	untreated	ADJ
bjp-62725	87	15	or	or	CCONJ
bjp-62725	87	16	given	give	VERB
bjp-62725	87	17	different	different	ADJ
bjp-62725	87	18	doses	dose	NOUN
bjp-62725	87	19	of	of	ADP
bjp-62725	87	20	colchicine	colchicine	PROPN
bjp-62725	87	21	.	.	PUNCT
bjp-62725	88	1	by	by	ADP
bjp-62725	88	2	using	use	VERB
bjp-62725	88	3	western	western	ADJ
bjp-62725	88	4	blot	blot	NOUN
bjp-62725	88	5	(	(	PUNCT
bjp-62725	88	6	c	c	NOUN
bjp-62725	88	7	)	)	PUNCT
bjp-62725	88	8	or	or	CCONJ
bjp-62725	88	9	rt	rt	NOUN
bjp-62725	88	10	-	-	PUNCT
bjp-62725	88	11	pcr	pcr	NOUN
bjp-62725	88	12	,	,	PUNCT
bjp-62725	88	13	the	the	DET
bjp-62725	88	14	expression	expression	NOUN
bjp-62725	88	15	levels	level	NOUN
bjp-62725	88	16	of	of	ADP
bjp-62725	88	17	tubulin	tubulin	NOUN
bjp-62725	88	18	,	,	PUNCT
bjp-62725	88	19	type	type	NOUN
bjp-62725	88	20	ii	ii	PROPN
bjp-62725	88	21	collagen	collagen	NOUN
bjp-62725	88	22	,	,	PUNCT
bjp-62725	88	23	aggrecan	aggrecan	ADJ
bjp-62725	88	24	,	,	PUNCT
bjp-62725	88	25	sox-9	sox-9	PRON
bjp-62725	88	26	,	,	PUNCT
bjp-62725	88	27	cox-2	cox-2	NOUN
bjp-62725	88	28	,	,	PUNCT
bjp-62725	88	29	and	and	CCONJ
bjp-62725	88	30	gapdh	gapdh	NOUN
bjp-62725	88	31	were	be	AUX
bjp-62725	88	32	examined	examine	VERB
bjp-62725	88	33	(	(	PUNCT
bjp-62725	88	34	d	d	NOUN
bjp-62725	88	35	)	)	PUNCT
bjp-62725	88	36	.	.	PUNCT
bjp-62725	89	1	gapdh	gapdh	NOUN
bjp-62725	89	2	was	be	AUX
bjp-62725	89	3	used	use	VERB
bjp-62725	89	4	as	as	ADP
bjp-62725	89	5	a	a	DET
bjp-62725	89	6	loading	loading	NOUN
bjp-62725	89	7	control	control	NOUN
bjp-62725	89	8	.	.	PUNCT
bjp-62725	90	1	(	(	PUNCT
bjp-62725	90	2	e	e	NOUN
bjp-62725	90	3	)	)	PUNCT
bjp-62725	90	4	for	for	ADP
bjp-62725	90	5	24	24	NUM
bjp-62725	90	6	hours	hour	NOUN
bjp-62725	90	7	,	,	PUNCT
bjp-62725	90	8	chondrocytes	chondrocyte	NOUN
bjp-62725	90	9	were	be	AUX
bjp-62725	90	10	either	either	CCONJ
bjp-62725	90	11	left	leave	VERB
bjp-62725	90	12	untreated	untreated	ADJ
bjp-62725	90	13	or	or	CCONJ
bjp-62725	90	14	given	give	VERB
bjp-62725	90	15	different	different	ADJ
bjp-62725	90	16	doses	dose	NOUN
bjp-62725	90	17	of	of	ADP
bjp-62725	90	18	colchicine	colchicine	PROPN
bjp-62725	90	19	.	.	PUNCT
bjp-62725	91	1	alcian	alcian	PROPN
bjp-62725	91	2	blue	blue	ADJ
bjp-62725	91	3	staining	stain	VERB
bjp-62725	91	4	was	be	AUX
bjp-62725	91	5	used	use	VERB
bjp-62725	91	6	to	to	PART
bjp-62725	91	7	assess	assess	VERB
bjp-62725	91	8	how	how	SCONJ
bjp-62725	91	9	sulfated	sulfated	ADJ
bjp-62725	91	10	proteoglycans	proteoglycan	NOUN
bjp-62725	91	11	were	be	AUX
bjp-62725	91	12	synthesized	synthesize	VERB
bjp-62725	91	13	.	.	PUNCT
bjp-62725	92	1	the	the	DET
bjp-62725	92	2	data	datum	NOUN
bjp-62725	92	3	in	in	ADP
bjp-62725	92	4	(	(	PUNCT
bjp-62725	92	5	a	a	PRON
bjp-62725	92	6	,	,	PUNCT
bjp-62725	92	7	b	b	NOUN
bjp-62725	92	8	,	,	PUNCT
bjp-62725	92	9	c	c	NOUN
bjp-62725	92	10	,	,	PUNCT
bjp-62725	92	11	d	d	NOUN
bjp-62725	92	12	,	,	PUNCT
bjp-62725	92	13	and	and	CCONJ
bjp-62725	92	14	e	e	X
bjp-62725	92	15	)	)	PUNCT
bjp-62725	92	16	indicate	indicate	VERB
bjp-62725	92	17	the	the	DET
bjp-62725	92	18	outcomes	outcome	NOUN
bjp-62725	92	19	of	of	ADP
bjp-62725	92	20	a	a	DET
bjp-62725	92	21	typical	typical	ADJ
bjp-62725	92	22	experiment	experiment	NOUN
bjp-62725	92	23	,	,	PUNCT
bjp-62725	92	24	whereas	whereas	SCONJ
bjp-62725	92	25	the	the	DET
bjp-62725	92	26	data	datum	NOUN
bjp-62725	92	27	in	in	ADP
bjp-62725	92	28	(	(	PUNCT
bjp-62725	92	29	e	e	NOUN
bjp-62725	92	30	)	)	PUNCT
bjp-62725	92	31	represent	represent	VERB
bjp-62725	92	32	mean	mean	ADJ
bjp-62725	92	33	values	value	NOUN
bjp-62725	92	34	with	with	ADP
bjp-62725	92	35	standard	standard	ADJ
bjp-62725	92	36	deviation	deviation	NOUN
bjp-62725	92	37	.	.	PUNCT
bjp-62725	93	1	*	*	PUNCT
bjp-62725	93	2	p<0.05	p<0.05	NOUN
bjp-62725	93	3	e	e	PROPN
bjp-62725	93	4	bangladesh	bangladesh	NOUN
bjp-62725	93	5	j	j	PROPN
bjp-62725	93	6	pharmacol	pharmacol	PROPN
bjp-62725	93	7	2023	2023	NUM
bjp-62725	93	8	;	;	PUNCT
bjp-62725	93	9	18	18	NUM
bjp-62725	93	10	:	:	SYM
bjp-62725	93	11	8	8	NUM
bjp-62725	93	12	-	-	SYM
bjp-62725	93	13	16	16	NUM
bjp-62725	93	14	11	11	NUM
bjp-62725	93	15	significantly	significantly	ADV
bjp-62725	93	16	reduced	reduce	VERB
bjp-62725	93	17	the	the	DET
bjp-62725	93	18	expression	expression	NOUN
bjp-62725	93	19	of	of	ADP
bjp-62725	93	20	cox-2	cox-2	NOUN
bjp-62725	93	21	and	and	CCONJ
bjp-62725	93	22	piκbα	piκbα	ADJ
bjp-62725	93	23	,	,	PUNCT
bjp-62725	93	24	but	but	CCONJ
bjp-62725	93	25	also	also	ADV
bjp-62725	93	26	that	that	SCONJ
bjp-62725	93	27	cox-2	cox-2	ADJ
bjp-62725	93	28	and	and	CCONJ
bjp-62725	93	29	piκbα	piκbα	NOUN
bjp-62725	93	30	increased	increase	VERB
bjp-62725	93	31	by	by	ADP
bjp-62725	93	32	colchicine	colchicine	PROPN
bjp-62725	93	33	were	be	AUX
bjp-62725	93	34	significantly	significantly	ADV
bjp-62725	93	35	reduced	reduce	VERB
bjp-62725	93	36	by	by	ADP
bjp-62725	93	37	bms	bms	PROPN
bjp-62725	93	38	345541	345541	NUM
bjp-62725	93	39	.	.	PUNCT
bjp-62725	94	1	the	the	DET
bjp-62725	94	2	changes	change	NOUN
bjp-62725	94	3	of	of	ADP
bjp-62725	94	4	piκbα	piκbα	NOUN
bjp-62725	94	5	,	,	PUNCT
bjp-62725	94	6	iκbα	iκbα	ADJ
bjp-62725	94	7	and	and	CCONJ
bjp-62725	94	8	β	β	NOUN
bjp-62725	94	9	-	-	ADJ
bjp-62725	94	10	catenin	catenin	NOUN
bjp-62725	94	11	identified	identify	VERB
bjp-62725	94	12	by	by	ADP
bjp-62725	94	13	western	western	ADJ
bjp-62725	94	14	blot	blot	NOUN
bjp-62725	94	15	suggest	suggest	VERB
bjp-62725	94	16	that	that	SCONJ
bjp-62725	94	17	the	the	DET
bjp-62725	94	18	nf	nf	NOUN
bjp-62725	94	19	-	-	PUNCT
bjp-62725	94	20	κb	κb	NOUN
bjp-62725	94	21	and	and	CCONJ
bjp-62725	94	22	β	β	NOUN
bjp-62725	94	23	-	-	ADJ
bjp-62725	94	24	catenin	catenin	ADJ
bjp-62725	94	25	pathway	pathway	NOUN
bjp-62725	94	26	involved	involve	VERB
bjp-62725	94	27	to	to	ADP
bjp-62725	94	28	inflammatory	inflammatory	ADJ
bjp-62725	94	29	and	and	CCONJ
bjp-62725	94	30	dedifferentiating	dedifferentiate	VERB
bjp-62725	94	31	effects	effect	NOUN
bjp-62725	94	32	via	via	ADP
bjp-62725	94	33	colchicine	colchicine	PROPN
bjp-62725	94	34	(	(	PUNCT
bjp-62725	94	35	figure	figure	VERB
bjp-62725	94	36	4b	4b	PROPN
bjp-62725	94	37	)	)	PUNCT
bjp-62725	94	38	.	.	PUNCT
bjp-62725	95	1	β	β	X
bjp-62725	95	2	-	-	ADJ
bjp-62725	95	3	catenin	catenin	ADJ
bjp-62725	95	4	pathway	pathway	NOUN
bjp-62725	95	5	to	to	PART
bjp-62725	95	6	induce	induce	VERB
bjp-62725	95	7	chondrocyte	chondrocyte	NOUN
bjp-62725	95	8	dedifferentiation	dedifferentiation	NOUN
bjp-62725	95	9	to	to	PART
bjp-62725	95	10	elaborately	elaborately	ADV
bjp-62725	95	11	study	study	VERB
bjp-62725	95	12	the	the	DET
bjp-62725	95	13	β	β	NOUN
bjp-62725	95	14	-	-	ADJ
bjp-62725	95	15	catenin	catenin	ADJ
bjp-62725	95	16	pathway	pathway	NOUN
bjp-62725	95	17	activated	activate	VERB
bjp-62725	95	18	by	by	ADP
bjp-62725	95	19	colchicine	colchicine	PROPN
bjp-62725	95	20	,	,	PUNCT
bjp-62725	95	21	sir	sir	NOUN
bjp-62725	95	22	β	β	NOUN
bjp-62725	95	23	-	-	NOUN
bjp-62725	95	24	catenin	catenin	NOUN
bjp-62725	95	25	and	and	CCONJ
bjp-62725	95	26	mg132	mg132	PROPN
bjp-62725	95	27	(	(	PUNCT
bjp-62725	95	28	β	β	NOUN
bjp-62725	95	29	-	-	ADJ
bjp-62725	95	30	catenin	catenin	ADJ
bjp-62725	95	31	activator	activator	NOUN
bjp-62725	95	32	)	)	PUNCT
bjp-62725	95	33	were	be	AUX
bjp-62725	95	34	treated	treat	VERB
bjp-62725	95	35	with	with	ADP
bjp-62725	95	36	chondrocytes	chondrocyte	NOUN
bjp-62725	95	37	and	and	CCONJ
bjp-62725	95	38	the	the	DET
bjp-62725	95	39	results	result	NOUN
bjp-62725	95	40	were	be	AUX
bjp-62725	95	41	confirmed	confirm	VERB
bjp-62725	95	42	with	with	ADP
bjp-62725	95	43	western	western	ADJ
bjp-62725	95	44	blot	blot	NOUN
bjp-62725	95	45	.	.	PUNCT
bjp-62725	96	1	the	the	DET
bjp-62725	96	2	reduction	reduction	NOUN
bjp-62725	96	3	in	in	ADP
bjp-62725	96	4	the	the	DET
bjp-62725	96	5	expression	expression	NOUN
bjp-62725	96	6	level	level	NOUN
bjp-62725	96	7	of	of	ADP
bjp-62725	96	8	β	β	NOUN
bjp-62725	96	9	-	-	NOUN
bjp-62725	96	10	catenin	catenin	NOUN
bjp-62725	96	11	was	be	AUX
bjp-62725	96	12	observed	observe	VERB
bjp-62725	96	13	in	in	ADP
bjp-62725	96	14	the	the	DET
bjp-62725	96	15	case	case	NOUN
bjp-62725	96	16	of	of	ADP
bjp-62725	96	17	sir	sir	PROPN
bjp-62725	96	18	β	β	NOUN
bjp-62725	96	19	-	-	ADJ
bjp-62725	96	20	catenin	catenin	ADJ
bjp-62725	96	21	treatment	treatment	NOUN
bjp-62725	96	22	which	which	PRON
bjp-62725	96	23	led	lead	VERB
bjp-62725	96	24	to	to	ADP
bjp-62725	96	25	differentiation	differentiation	NOUN
bjp-62725	96	26	cotreated	cotreate	VERB
bjp-62725	96	27	with	with	ADP
bjp-62725	96	28	colchicine	colchicine	PROPN
bjp-62725	96	29	(	(	PUNCT
bjp-62725	96	30	figure	figure	NOUN
bjp-62725	96	31	5a	5a	NUM
bjp-62725	96	32	)	)	PUNCT
bjp-62725	96	33	.	.	PUNCT
bjp-62725	97	1	these	these	DET
bjp-62725	97	2	results	result	NOUN
bjp-62725	97	3	were	be	AUX
bjp-62725	97	4	also	also	ADV
bjp-62725	97	5	cross	cross	ADJ
bjp-62725	97	6	-	-	ADJ
bjp-62725	97	7	confirmed	confirm	VERB
bjp-62725	97	8	with	with	ADP
bjp-62725	97	9	immunofluorescence	immunofluorescence	NOUN
bjp-62725	97	10	staining	stain	VERB
bjp-62725	97	11	(	(	PUNCT
bjp-62725	97	12	figure	figure	NOUN
bjp-62725	97	13	5b	5b	NUM
bjp-62725	97	14	)	)	PUNCT
bjp-62725	97	15	.	.	PUNCT
bjp-62725	98	1	conversely	conversely	ADV
bjp-62725	98	2	,	,	PUNCT
bjp-62725	98	3	when	when	SCONJ
bjp-62725	98	4	the	the	DET
bjp-62725	98	5	accumulation	accumulation	NOUN
bjp-62725	98	6	of	of	ADP
bjp-62725	98	7	β	β	NOUN
bjp-62725	98	8	-	-	NOUN
bjp-62725	98	9	catenin	catenin	NOUN
bjp-62725	98	10	in	in	ADP
bjp-62725	98	11	chondrocytes	chondrocyte	NOUN
bjp-62725	98	12	was	be	AUX
bjp-62725	98	13	induced	induce	VERB
bjp-62725	98	14	by	by	ADP
bjp-62725	98	15	treatment	treatment	NOUN
bjp-62725	98	16	with	with	ADP
bjp-62725	98	17	mg132	mg132	PROPN
bjp-62725	98	18	,	,	PUNCT
bjp-62725	98	19	it	it	PRON
bjp-62725	98	20	was	be	AUX
bjp-62725	98	21	confirmed	confirm	VERB
bjp-62725	98	22	that	that	SCONJ
bjp-62725	98	23	the	the	DET
bjp-62725	98	24	chondrocytes	chondrocyte	NOUN
bjp-62725	98	25	were	be	AUX
bjp-62725	98	26	de	de	ADJ
bjp-62725	98	27	-	-	ADJ
bjp-62725	98	28	differentiated	differentiated	ADJ
bjp-62725	98	29	due	due	ADP
bjp-62725	98	30	to	to	ADP
bjp-62725	98	31	the	the	DET
bjp-62725	98	32	decrease	decrease	NOUN
bjp-62725	98	33	of	of	ADP
bjp-62725	98	34	type	type	NOUN
bjp-62725	98	35	ii	ii	PROPN
bjp-62725	98	36	collagen	collagen	NOUN
bjp-62725	98	37	.	.	PUNCT
bjp-62725	99	1	furthermore	furthermore	ADV
bjp-62725	99	2	,	,	PUNCT
bjp-62725	99	3	it	it	PRON
bjp-62725	99	4	was	be	AUX
bjp-62725	99	5	confirmed	confirm	VERB
bjp-62725	99	6	that	that	SCONJ
bjp-62725	99	7	the	the	DET
bjp-62725	99	8	simultaneous	simultaneous	ADJ
bjp-62725	99	9	treatment	treatment	NOUN
bjp-62725	99	10	of	of	ADP
bjp-62725	99	11	mg132	mg132	PROPN
bjp-62725	99	12	and	and	CCONJ
bjp-62725	99	13	colchicine	colchicine	PROPN
bjp-62725	99	14	further	far	ADV
bjp-62725	99	15	increased	increase	VERB
bjp-62725	99	16	the	the	DET
bjp-62725	99	17	accumulation	accumulation	NOUN
bjp-62725	99	18	of	of	ADP
bjp-62725	99	19	β	β	NOUN
bjp-62725	99	20	-	-	NOUN
bjp-62725	99	21	catenin	catenin	NOUN
bjp-62725	99	22	in	in	ADP
bjp-62725	99	23	chondrocytes	chondrocyte	NOUN
bjp-62725	99	24	,	,	PUNCT
bjp-62725	99	25	thereby	thereby	ADV
bjp-62725	99	26	accelerating	accelerate	VERB
bjp-62725	99	27	the	the	DET
bjp-62725	99	28	de	de	NOUN
bjp-62725	99	29	-	-	NOUN
bjp-62725	99	30	differentiation	differentiation	NOUN
bjp-62725	99	31	of	of	ADP
bjp-62725	99	32	chondrocytes	chondrocyte	NOUN
bjp-62725	99	33	.	.	PUNCT
bjp-62725	100	1	identical	identical	ADJ
bjp-62725	100	2	to	to	ADP
bjp-62725	100	3	western	western	ADJ
bjp-62725	100	4	blot	blot	NOUN
bjp-62725	100	5	results	result	NOUN
bjp-62725	100	6	,	,	PUNCT
bjp-62725	100	7	co	co	NOUN
bjp-62725	100	8	-	-	NOUN
bjp-62725	100	9	treatment	treatment	NOUN
bjp-62725	100	10	of	of	ADP
bjp-62725	100	11	colchicine	colchicine	NOUN
bjp-62725	100	12	with	with	ADP
bjp-62725	100	13	sir	sir	PROPN
bjp-62725	100	14	β	β	PROPN
bjp-62725	100	15	-	-	ADJ
bjp-62725	100	16	catenin	catenin	NOUN
bjp-62725	100	17	increased	increase	VERB
bjp-62725	100	18	the	the	DET
bjp-62725	100	19	differentiation	differentiation	NOUN
bjp-62725	100	20	of	of	ADP
bjp-62725	100	21	chondrocytes	chondrocyte	NOUN
bjp-62725	100	22	as	as	SCONJ
bjp-62725	100	23	compared	compare	VERB
bjp-62725	100	24	to	to	ADP
bjp-62725	100	25	colchicine	colchicine	NOUN
bjp-62725	100	26	treatment	treatment	NOUN
bjp-62725	100	27	alone	alone	ADV
bjp-62725	100	28	(	(	PUNCT
bjp-62725	100	29	figure	figure	NOUN
bjp-62725	100	30	5b	5b	NUM
bjp-62725	100	31	)	)	PUNCT
bjp-62725	100	32	.	.	PUNCT
bjp-62725	101	1	in	in	ADP
bjp-62725	101	2	addition	addition	NOUN
bjp-62725	101	3	,	,	PUNCT
bjp-62725	101	4	βcatenin	βcatenin	X
bjp-62725	101	5	,	,	PUNCT
bjp-62725	101	6	which	which	PRON
bjp-62725	101	7	is	be	AUX
bjp-62725	101	8	intensively	intensively	ADV
bjp-62725	101	9	distributed	distribute	VERB
bjp-62725	101	10	in	in	ADP
bjp-62725	101	11	the	the	DET
bjp-62725	101	12	cell	cell	NOUN
bjp-62725	101	13	membrane	membrane	NOUN
bjp-62725	101	14	,	,	PUNCT
bjp-62725	101	15	was	be	AUX
bjp-62725	101	16	greatly	greatly	ADV
bjp-62725	101	17	increased	increase	VERB
bjp-62725	101	18	inside	inside	ADP
bjp-62725	101	19	the	the	DET
bjp-62725	101	20	cytoplasm	cytoplasm	NOUN
bjp-62725	101	21	by	by	ADP
bjp-62725	101	22	treatment	treatment	NOUN
bjp-62725	101	23	with	with	ADP
bjp-62725	101	24	colchicine	colchicine	NOUN
bjp-62725	101	25	.	.	PUNCT
bjp-62725	102	1	however	however	ADV
bjp-62725	102	2	,	,	PUNCT
bjp-62725	102	3	treatment	treatment	NOUN
bjp-62725	102	4	with	with	ADP
bjp-62725	102	5	sir	sir	PROPN
bjp-62725	102	6	β	β	NOUN
bjp-62725	102	7	-	-	NOUN
bjp-62725	102	8	catenin	catenin	NOUN
bjp-62725	102	9	reduced	reduce	VERB
bjp-62725	102	10	the	the	DET
bjp-62725	102	11	expression	expression	NOUN
bjp-62725	102	12	of	of	ADP
bjp-62725	102	13	β	β	NOUN
bjp-62725	102	14	-	-	ADJ
bjp-62725	102	15	catenin	catenin	NOUN
bjp-62725	102	16	increased	increase	VERB
bjp-62725	102	17	by	by	ADP
bjp-62725	102	18	colchicine	colchicine	PROPN
bjp-62725	102	19	and	and	CCONJ
bjp-62725	102	20	also	also	ADV
bjp-62725	102	21	restored	restore	VERB
bjp-62725	102	22	the	the	DET
bjp-62725	102	23	expression	expression	NOUN
bjp-62725	102	24	of	of	ADP
bjp-62725	102	25	type	type	NOUN
bjp-62725	102	26	ii	ii	PROPN
bjp-62725	102	27	collagen	collagen	NOUN
bjp-62725	102	28	(	(	PUNCT
bjp-62725	102	29	figure	figure	NOUN
bjp-62725	102	30	5b	5b	NUM
bjp-62725	102	31	)	)	PUNCT
bjp-62725	102	32	.	.	PUNCT
bjp-62725	103	1	this	this	PRON
bjp-62725	103	2	suggests	suggest	VERB
bjp-62725	103	3	that	that	SCONJ
bjp-62725	103	4	colchicine	colchicine	PROPN
bjp-62725	103	5	treatment	treatment	NOUN
bjp-62725	103	6	modulated	modulate	VERB
bjp-62725	103	7	β	β	NOUN
bjp-62725	103	8	-	-	ADJ
bjp-62725	103	9	catenin	catenin	ADJ
bjp-62725	103	10	pathway	pathway	NOUN
bjp-62725	103	11	to	to	PART
bjp-62725	103	12	disrupt	disrupt	VERB
bjp-62725	103	13	microtubule	microtubule	NOUN
bjp-62725	103	14	synthesis	synthesis	NOUN
bjp-62725	103	15	in	in	ADP
bjp-62725	103	16	chondrocytes	chondrocyte	NOUN
bjp-62725	103	17	and	and	CCONJ
bjp-62725	103	18	thereby	thereby	ADV
bjp-62725	103	19	inducing	induce	VERB
bjp-62725	103	20	chondrocyte	chondrocyte	ADJ
bjp-62725	103	21	dedifferentiation	dedifferentiation	NOUN
bjp-62725	103	22	(	(	PUNCT
bjp-62725	103	23	figure	figure	NOUN
bjp-62725	103	24	5	5	NUM
bjp-62725	103	25	)	)	PUNCT
bjp-62725	103	26	.	.	PUNCT
bjp-62725	104	1	inflammation	inflammation	NOUN
bjp-62725	104	2	and	and	CCONJ
bjp-62725	104	3	differentiation	differentiation	NOUN
bjp-62725	104	4	as	as	SCONJ
bjp-62725	104	5	described	describe	VERB
bjp-62725	104	6	in	in	ADP
bjp-62725	104	7	figure	figure	NOUN
bjp-62725	104	8	3	3	NUM
bjp-62725	104	9	,	,	PUNCT
bjp-62725	104	10	to	to	PART
bjp-62725	104	11	understand	understand	VERB
bjp-62725	104	12	the	the	DET
bjp-62725	104	13	mechanism	mechanism	NOUN
bjp-62725	104	14	of	of	ADP
bjp-62725	104	15	colchicine	colchicine	PROPN
bjp-62725	104	16	was	be	AUX
bjp-62725	104	17	used	use	VERB
bjp-62725	104	18	paclitaxel	paclitaxel	NOUN
bjp-62725	104	19	,	,	PUNCT
bjp-62725	104	20	which	which	PRON
bjp-62725	104	21	had	have	VERB
bjp-62725	104	22	the	the	DET
bjp-62725	104	23	opposite	opposite	ADJ
bjp-62725	104	24	mechanism	mechanism	NOUN
bjp-62725	104	25	of	of	ADP
bjp-62725	104	26	action	action	NOUN
bjp-62725	104	27	than	than	ADP
bjp-62725	104	28	that	that	PRON
bjp-62725	104	29	of	of	ADP
bjp-62725	104	30	colchicine	colchicine	PROPN
bjp-62725	104	31	(	(	PUNCT
bjp-62725	104	32	figure	figure	VERB
bjp-62725	104	33	6a	6a	NOUN
bjp-62725	104	34	)	)	PUNCT
bjp-62725	104	35	.	.	PUNCT
bjp-62725	105	1	as	as	SCONJ
bjp-62725	105	2	expected	expect	VERB
bjp-62725	105	3	,	,	PUNCT
bjp-62725	105	4	colchicine	colchicine	PROPN
bjp-62725	105	5	ameliorated	ameliorate	VERB
bjp-62725	105	6	the	the	DET
bjp-62725	105	7	β	β	NOUN
bjp-62725	105	8	-	-	ADJ
bjp-62725	105	9	catenin	catenin	ADJ
bjp-62725	105	10	expression	expression	NOUN
bjp-62725	105	11	by	by	ADP
bjp-62725	105	12	decreasing	decrease	VERB
bjp-62725	105	13	the	the	DET
bjp-62725	105	14	phosphorylation	phosphorylation	NOUN
bjp-62725	105	15	of	of	ADP
bjp-62725	105	16	gsk3αβ	gsk3αβ	NOUN
bjp-62725	105	17	tyrosine	tyrosine	NOUN
bjp-62725	105	18	and	and	CCONJ
bjp-62725	105	19	serine	serine	NOUN
bjp-62725	105	20	residues	residue	NOUN
bjp-62725	105	21	while	while	SCONJ
bjp-62725	105	22	paclitaxel	paclitaxel	PROPN
bjp-62725	105	23	increased	increase	VERB
bjp-62725	105	24	the	the	DET
bjp-62725	105	25	phosphorylation	phosphorylation	NOUN
bjp-62725	105	26	of	of	ADP
bjp-62725	105	27	gsk-3αβ	gsk-3αβ	NOUN
bjp-62725	105	28	tyrosine	tyrosine	NOUN
bjp-62725	105	29	and	and	CCONJ
bjp-62725	105	30	serine	serine	NOUN
bjp-62725	105	31	residues	residue	NOUN
bjp-62725	105	32	.	.	PUNCT
bjp-62725	106	1	when	when	SCONJ
bjp-62725	106	2	these	these	DET
bjp-62725	106	3	two	two	NUM
bjp-62725	106	4	were	be	AUX
bjp-62725	106	5	treated	treat	VERB
bjp-62725	106	6	together	together	ADV
bjp-62725	106	7	,	,	PUNCT
bjp-62725	106	8	paclitaxel	paclitaxel	NOUN
bjp-62725	106	9	not	not	PART
bjp-62725	106	10	only	only	ADV
bjp-62725	106	11	suppressed	suppress	VERB
bjp-62725	106	12	the	the	DET
bjp-62725	106	13	expression	expression	NOUN
bjp-62725	106	14	of	of	ADP
bjp-62725	106	15	βcatenin	βcatenin	NOUN
bjp-62725	106	16	but	but	CCONJ
bjp-62725	106	17	also	also	ADV
bjp-62725	106	18	augmented	augment	VERB
bjp-62725	106	19	the	the	DET
bjp-62725	106	20	phosphorylation	phosphorylation	NOUN
bjp-62725	106	21	of	of	ADP
bjp-62725	106	22	gsk-3αβ	gsk-3αβ	NOUN
bjp-62725	106	23	serine	serine	NOUN
bjp-62725	106	24	residues	residue	NOUN
bjp-62725	106	25	(	(	PUNCT
bjp-62725	106	26	figure	figure	NOUN
bjp-62725	106	27	5b	5b	NUM
bjp-62725	106	28	)	)	PUNCT
bjp-62725	106	29	.	.	PUNCT
bjp-62725	107	1	in	in	ADP
bjp-62725	107	2	addition	addition	NOUN
bjp-62725	107	3	,	,	PUNCT
bjp-62725	107	4	paclitaxel	paclitaxel	PROPN
bjp-62725	107	5	,	,	PUNCT
bjp-62725	107	6	which	which	PRON
bjp-62725	107	7	induces	induce	VERB
bjp-62725	107	8	the	the	DET
bjp-62725	107	9	polymerization	polymerization	NOUN
bjp-62725	107	10	of	of	ADP
bjp-62725	107	11	microtubules	microtubule	NOUN
bjp-62725	107	12	as	as	SCONJ
bjp-62725	107	13	opposed	oppose	VERB
bjp-62725	107	14	to	to	ADP
bjp-62725	107	15	colchicine	colchicine	PROPN
bjp-62725	107	16	,	,	PUNCT
bjp-62725	107	17	showed	show	VERB
bjp-62725	107	18	similar	similar	ADJ
bjp-62725	107	19	results	result	NOUN
bjp-62725	107	20	as	as	ADP
bjp-62725	107	21	bms	bms	NOUN
bjp-62725	107	22	345541	345541	NUM
bjp-62725	107	23	treatment	treatment	NOUN
bjp-62725	107	24	.	.	PUNCT
bjp-62725	108	1	the	the	DET
bjp-62725	108	2	expression	expression	NOUN
bjp-62725	108	3	level	level	NOUN
bjp-62725	108	4	of	of	ADP
bjp-62725	108	5	cox2	cox2	NOUN
bjp-62725	108	6	and	and	CCONJ
bjp-62725	108	7	phosphorylation	phosphorylation	NOUN
bjp-62725	108	8	of	of	ADP
bjp-62725	108	9	iκbα	iκbα	ADV
bjp-62725	108	10	were	be	AUX
bjp-62725	108	11	decreased	decrease	VERB
bjp-62725	108	12	by	by	ADP
bjp-62725	108	13	paclitaxel	paclitaxel	PROPN
bjp-62725	108	14	(	(	PUNCT
bjp-62725	108	15	figure	figure	NOUN
bjp-62725	108	16	6b	6b	NUM
bjp-62725	108	17	)	)	PUNCT
bjp-62725	108	18	.	.	PUNCT
bjp-62725	109	1	figure	figure	VERB
bjp-62725	109	2	2	2	NUM
bjp-62725	109	3	:	:	PUNCT
bjp-62725	109	4	in	in	ADP
bjp-62725	109	5	rabbit	rabbit	NOUN
bjp-62725	109	6	articular	articular	ADJ
bjp-62725	109	7	chondrocytes	chondrocyte	NOUN
bjp-62725	109	8	,	,	PUNCT
bjp-62725	109	9	colchicine	colchicine	PROPN
bjp-62725	109	10	decreases	decrease	VERB
bjp-62725	109	11	tubulin	tubulin	NOUN
bjp-62725	109	12	production	production	NOUN
bjp-62725	109	13	and	and	CCONJ
bjp-62725	109	14	chondrocyte	chondrocyte	NOUN
bjp-62725	109	15	differentiation	differentiation	NOUN
bjp-62725	109	16	.	.	PUNCT
bjp-62725	110	1	for	for	ADP
bjp-62725	110	2	24	24	NUM
bjp-62725	110	3	hours	hour	NOUN
bjp-62725	110	4	,	,	PUNCT
bjp-62725	110	5	chondrocytes	chondrocyte	NOUN
bjp-62725	110	6	were	be	AUX
bjp-62725	110	7	either	either	CCONJ
bjp-62725	110	8	left	leave	VERB
bjp-62725	110	9	untreated	untreated	ADJ
bjp-62725	110	10	or	or	CCONJ
bjp-62725	110	11	given	give	VERB
bjp-62725	110	12	1	1	NUM
bjp-62725	110	13	mm	mm	PROPN
bjp-62725	110	14	colchicine	colchicine	NOUN
bjp-62725	110	15	.	.	PUNCT
bjp-62725	111	1	using	use	VERB
bjp-62725	111	2	immunofluorescence	immunofluorescence	NOUN
bjp-62725	111	3	staining	stain	VERB
bjp-62725	111	4	,	,	PUNCT
bjp-62725	111	5	it	it	PRON
bjp-62725	111	6	was	be	AUX
bjp-62725	111	7	possible	possible	ADJ
bjp-62725	111	8	to	to	PART
bjp-62725	111	9	measure	measure	VERB
bjp-62725	111	10	the	the	DET
bjp-62725	111	11	expression	expression	NOUN
bjp-62725	111	12	of	of	ADP
bjp-62725	111	13	type	type	NOUN
bjp-62725	111	14	ii	ii	PROPN
bjp-62725	111	15	collagen	collagen	NOUN
bjp-62725	111	16	and	and	CCONJ
bjp-62725	111	17	tubulin	tubulin	NOUN
bjp-62725	111	18	.	.	PUNCT
bjp-62725	112	1	cells	cell	NOUN
bjp-62725	112	2	were	be	AUX
bjp-62725	112	3	labelled	label	VERB
bjp-62725	112	4	with	with	ADP
bjp-62725	112	5	a	a	DET
bjp-62725	112	6	particular	particular	ADJ
bjp-62725	112	7	antibody	antibody	NOUN
bjp-62725	112	8	(	(	PUNCT
bjp-62725	112	9	red	red	ADJ
bjp-62725	112	10	or	or	CCONJ
bjp-62725	112	11	green	green	ADJ
bjp-62725	112	12	)	)	PUNCT
bjp-62725	112	13	and	and	CCONJ
bjp-62725	112	14	dapi	dapi	ADJ
bjp-62725	112	15	for	for	ADP
bjp-62725	112	16	nuclear	nuclear	ADJ
bjp-62725	112	17	staining	stain	VERB
bjp-62725	112	18	(	(	PUNCT
bjp-62725	112	19	blue	blue	ADJ
bjp-62725	112	20	)	)	PUNCT
bjp-62725	112	21	.	.	PUNCT
bjp-62725	113	1	magnification	magnification	NOUN
bjp-62725	113	2	×400	×400	NOUN
bjp-62725	113	3	12	12	NUM
bjp-62725	113	4	bangladesh	bangladesh	PROPN
bjp-62725	113	5	j	j	PROPN
bjp-62725	113	6	pharmacol	pharmacol	PROPN
bjp-62725	113	7	2023	2023	NUM
bjp-62725	113	8	;	;	PUNCT
bjp-62725	113	9	18	18	NUM
bjp-62725	113	10	:	:	SYM
bjp-62725	113	11	8	8	NUM
bjp-62725	113	12	-	-	SYM
bjp-62725	113	13	16	16	NUM
bjp-62725	113	14	discussion	discussion	NOUN
bjp-62725	113	15	this	this	DET
bjp-62725	113	16	study	study	NOUN
bjp-62725	113	17	evaluated	evaluate	VERB
bjp-62725	113	18	the	the	DET
bjp-62725	113	19	specific	specific	ADJ
bjp-62725	113	20	role	role	NOUN
bjp-62725	113	21	that	that	PRON
bjp-62725	113	22	microtubules	microtubule	NOUN
bjp-62725	113	23	may	may	AUX
bjp-62725	113	24	play	play	VERB
bjp-62725	113	25	in	in	ADP
bjp-62725	113	26	determining	determine	VERB
bjp-62725	113	27	chondrocyte	chondrocyte	NOUN
bjp-62725	113	28	differentiation	differentiation	NOUN
bjp-62725	113	29	using	use	VERB
bjp-62725	113	30	two	two	NUM
bjp-62725	113	31	well	well	ADV
bjp-62725	113	32	-	-	PUNCT
bjp-62725	113	33	studied	study	VERB
bjp-62725	113	34	microtubule	microtubule	NOUN
bjp-62725	113	35	reagents	reagent	NOUN
bjp-62725	113	36	,	,	PUNCT
bjp-62725	113	37	colchicine	colchicine	NOUN
bjp-62725	113	38	,	,	PUNCT
bjp-62725	113	39	and	and	CCONJ
bjp-62725	113	40	paclitaxel	paclitaxel	PROPN
bjp-62725	113	41	.	.	PUNCT
bjp-62725	114	1	the	the	DET
bjp-62725	114	2	treatment	treatment	NOUN
bjp-62725	114	3	of	of	ADP
bjp-62725	114	4	colchicine	colchicine	PROPN
bjp-62725	114	5	showed	show	VERB
bjp-62725	114	6	a	a	DET
bjp-62725	114	7	dramatic	dramatic	ADJ
bjp-62725	114	8	dedifferentiation	dedifferentiation	NOUN
bjp-62725	114	9	effect	effect	NOUN
bjp-62725	114	10	in	in	ADP
bjp-62725	114	11	chondrocytes	chondrocyte	NOUN
bjp-62725	114	12	in	in	ADP
bjp-62725	114	13	the	the	DET
bjp-62725	114	14	present	present	NOUN
bjp-62725	114	15	c	c	PROPN
bjp-62725	114	16	b	b	PROPN
bjp-62725	114	17	a	a	DET
bjp-62725	114	18	d	d	NOUN
bjp-62725	114	19	figure	figure	NOUN
bjp-62725	114	20	3	3	NUM
bjp-62725	114	21	:	:	PUNCT
bjp-62725	114	22	regulation	regulation	NOUN
bjp-62725	114	23	of	of	ADP
bjp-62725	114	24	microtubule	microtubule	NOUN
bjp-62725	114	25	synthesis	synthesis	NOUN
bjp-62725	114	26	controls	control	VERB
bjp-62725	114	27	the	the	DET
bjp-62725	114	28	differentiation	differentiation	NOUN
bjp-62725	114	29	of	of	ADP
bjp-62725	114	30	chondrocytes	chondrocyte	NOUN
bjp-62725	114	31	and	and	CCONJ
bjp-62725	114	32	expression	expression	NOUN
bjp-62725	114	33	levels	level	NOUN
bjp-62725	114	34	of	of	ADP
bjp-62725	114	35	cox-2	cox-2	ADJ
bjp-62725	114	36	chondrocytes	chondrocyte	NOUN
bjp-62725	114	37	were	be	AUX
bjp-62725	114	38	either	either	CCONJ
bjp-62725	114	39	left	leave	VERB
bjp-62725	114	40	untreated	untreated	ADJ
bjp-62725	114	41	or	or	CCONJ
bjp-62725	114	42	pre	pre	VERB
bjp-62725	114	43	-	-	VERB
bjp-62725	114	44	treated	treat	VERB
bjp-62725	114	45	with	with	ADP
bjp-62725	114	46	5	5	NUM
bjp-62725	114	47	m	m	NOUN
bjp-62725	114	48	taxol	taxol	NOUN
bjp-62725	114	49	for	for	ADP
bjp-62725	114	50	2	2	NUM
bjp-62725	114	51	hours	hour	NOUN
bjp-62725	114	52	before	before	ADP
bjp-62725	114	53	being	be	AUX
bjp-62725	114	54	exposed	expose	VERB
bjp-62725	114	55	to	to	ADP
bjp-62725	114	56	1	1	NUM
bjp-62725	114	57	m	m	NOUN
bjp-62725	114	58	colchicine	colchicine	NOUN
bjp-62725	114	59	for	for	ADP
bjp-62725	114	60	24	24	NUM
bjp-62725	114	61	hours	hour	NOUN
bjp-62725	114	62	(	(	PUNCT
bjp-62725	114	63	a	a	DET
bjp-62725	114	64	,	,	PUNCT
bjp-62725	114	65	b	b	NOUN
bjp-62725	114	66	,	,	PUNCT
bjp-62725	114	67	and	and	CCONJ
bjp-62725	114	68	c	c	NOUN
bjp-62725	114	69	)	)	PUNCT
bjp-62725	114	70	.	.	PUNCT
bjp-62725	115	1	(	(	PUNCT
bjp-62725	115	2	a	a	X
bjp-62725	115	3	)	)	PUNCT
bjp-62725	115	4	immunofluorescence	immunofluorescence	NOUN
bjp-62725	115	5	labeling	labeling	NOUN
bjp-62725	115	6	was	be	AUX
bjp-62725	115	7	used	use	VERB
bjp-62725	115	8	to	to	PART
bjp-62725	115	9	identify	identify	VERB
bjp-62725	115	10	the	the	DET
bjp-62725	115	11	expression	expression	NOUN
bjp-62725	115	12	of	of	ADP
bjp-62725	115	13	type	type	NOUN
bjp-62725	115	14	ii	ii	PROPN
bjp-62725	115	15	collagen	collagen	NOUN
bjp-62725	115	16	and	and	CCONJ
bjp-62725	115	17	tubulin	tubulin	NOUN
bjp-62725	115	18	.	.	PUNCT
bjp-62725	116	1	cells	cell	NOUN
bjp-62725	116	2	were	be	AUX
bjp-62725	116	3	labeled	label	VERB
bjp-62725	116	4	with	with	ADP
bjp-62725	116	5	a	a	DET
bjp-62725	116	6	particular	particular	ADJ
bjp-62725	116	7	antibody	antibody	NOUN
bjp-62725	116	8	(	(	PUNCT
bjp-62725	116	9	red	red	ADJ
bjp-62725	116	10	or	or	CCONJ
bjp-62725	116	11	green	green	ADJ
bjp-62725	116	12	)	)	PUNCT
bjp-62725	116	13	and	and	CCONJ
bjp-62725	116	14	dapi	dapi	ADJ
bjp-62725	116	15	for	for	ADP
bjp-62725	116	16	nuclear	nuclear	ADJ
bjp-62725	116	17	staining	stain	VERB
bjp-62725	116	18	(	(	PUNCT
bjp-62725	116	19	blue	blue	ADJ
bjp-62725	116	20	)	)	PUNCT
bjp-62725	116	21	.	.	PUNCT
bjp-62725	117	1	400	400	NUM
bjp-62725	117	2	times	time	NOUN
bjp-62725	117	3	magnification	magnification	NOUN
bjp-62725	117	4	;	;	PUNCT
bjp-62725	117	5	(	(	PUNCT
bjp-62725	117	6	b	b	NOUN
bjp-62725	117	7	and	and	CCONJ
bjp-62725	117	8	c	c	NOUN
bjp-62725	117	9	)	)	PUNCT
bjp-62725	117	10	western	western	ADJ
bjp-62725	117	11	blot	blot	NOUN
bjp-62725	117	12	analysis	analysis	NOUN
bjp-62725	117	13	(	(	PUNCT
bjp-62725	117	14	b	b	NOUN
bjp-62725	117	15	)	)	PUNCT
bjp-62725	117	16	was	be	AUX
bjp-62725	117	17	used	use	VERB
bjp-62725	117	18	to	to	PART
bjp-62725	117	19	assess	assess	VERB
bjp-62725	117	20	the	the	DET
bjp-62725	117	21	expression	expression	NOUN
bjp-62725	117	22	of	of	ADP
bjp-62725	117	23	tubulin	tubulin	NOUN
bjp-62725	117	24	,	,	PUNCT
bjp-62725	117	25	type	type	NOUN
bjp-62725	117	26	ii	ii	PROPN
bjp-62725	117	27	collagen	collagen	NOUN
bjp-62725	117	28	,	,	PUNCT
bjp-62725	117	29	aggrecan	aggrecan	ADJ
bjp-62725	117	30	,	,	PUNCT
bjp-62725	117	31	sox-9	sox-9	PRON
bjp-62725	117	32	,	,	PUNCT
bjp-62725	117	33	cox-2	cox-2	NOUN
bjp-62725	117	34	,	,	PUNCT
bjp-62725	117	35	and	and	CCONJ
bjp-62725	117	36	gapdh	gapdh	NOUN
bjp-62725	117	37	.	.	PUNCT
bjp-62725	118	1	reverse	reverse	ADJ
bjp-62725	118	2	transcriptase	transcriptase	NOUN
bjp-62725	118	3	-	-	PUNCT
bjp-62725	118	4	polymerase	polymerase	NOUN
bjp-62725	118	5	chain	chain	NOUN
bjp-62725	118	6	reaction	reaction	NOUN
bjp-62725	118	7	(	(	PUNCT
bjp-62725	118	8	rt	rt	NOUN
bjp-62725	118	9	-	-	PUNCT
bjp-62725	118	10	pcr	pcr	NOUN
bjp-62725	118	11	)	)	PUNCT
bjp-62725	118	12	was	be	AUX
bjp-62725	118	13	used	use	VERB
bjp-62725	118	14	to	to	PART
bjp-62725	118	15	identify	identify	VERB
bjp-62725	118	16	the	the	DET
bjp-62725	118	17	expression	expression	NOUN
bjp-62725	118	18	of	of	ADP
bjp-62725	118	19	tubulin	tubulin	NOUN
bjp-62725	118	20	,	,	PUNCT
bjp-62725	118	21	type	type	NOUN
bjp-62725	118	22	ii	ii	PROPN
bjp-62725	118	23	collagen	collagen	NOUN
bjp-62725	118	24	,	,	PUNCT
bjp-62725	118	25	cox-2	cox-2	NOUN
bjp-62725	118	26	,	,	PUNCT
bjp-62725	118	27	and	and	CCONJ
bjp-62725	118	28	gapdh	gapdh	NOUN
bjp-62725	118	29	(	(	PUNCT
bjp-62725	118	30	c	c	NOUN
bjp-62725	118	31	)	)	PUNCT
bjp-62725	118	32	.	.	PUNCT
bjp-62725	119	1	we	we	PRON
bjp-62725	119	2	used	use	VERB
bjp-62725	119	3	gapdh	gapdh	NOUN
bjp-62725	119	4	as	as	ADP
bjp-62725	119	5	a	a	DET
bjp-62725	119	6	loading	loading	NOUN
bjp-62725	119	7	control	control	NOUN
bjp-62725	119	8	.	.	PUNCT
bjp-62725	120	1	(	(	PUNCT
bjp-62725	120	2	d	d	X
bjp-62725	120	3	)	)	PUNCT
bjp-62725	120	4	alcian	alcian	PROPN
bjp-62725	120	5	blue	blue	ADJ
bjp-62725	120	6	staining	stain	VERB
bjp-62725	120	7	was	be	AUX
bjp-62725	120	8	used	use	VERB
bjp-62725	120	9	to	to	PART
bjp-62725	120	10	assess	assess	VERB
bjp-62725	120	11	how	how	SCONJ
bjp-62725	120	12	sulphated	sulphated	ADJ
bjp-62725	120	13	proteoglycans	proteoglycan	NOUN
bjp-62725	120	14	were	be	AUX
bjp-62725	120	15	synthesized	synthesize	VERB
bjp-62725	120	16	.	.	PUNCT
bjp-62725	121	1	the	the	DET
bjp-62725	121	2	data	datum	NOUN
bjp-62725	121	3	are	be	AUX
bjp-62725	121	4	the	the	DET
bjp-62725	121	5	average	average	ADJ
bjp-62725	121	6	values	value	NOUN
bjp-62725	121	7	,	,	PUNCT
bjp-62725	121	8	plus	plus	CCONJ
bjp-62725	121	9	standard	standard	ADJ
bjp-62725	121	10	deviation	deviation	NOUN
bjp-62725	121	11	,	,	PUNCT
bjp-62725	121	12	from	from	ADP
bjp-62725	121	13	at	at	ADV
bjp-62725	121	14	least	least	ADV
bjp-62725	121	15	four	four	NUM
bjp-62725	121	16	independent	independent	ADJ
bjp-62725	121	17	studies	study	NOUN
bjp-62725	121	18	;	;	PUNCT
bjp-62725	121	19	*	*	PUNCT
bjp-62725	121	20	p	p	X
bjp-62725	121	21	<	<	X
bjp-62725	121	22	0.05	0.05	NUM
bjp-62725	121	23	in	in	ADP
bjp-62725	121	24	comparison	comparison	NOUN
bjp-62725	121	25	to	to	ADP
bjp-62725	121	26	the	the	DET
bjp-62725	121	27	control	control	NOUN
bjp-62725	121	28	group	group	NOUN
bjp-62725	121	29	.	.	PUNCT
bjp-62725	122	1	the	the	DET
bjp-62725	122	2	data	datum	NOUN
bjp-62725	122	3	in	in	ADP
bjp-62725	122	4	(	(	PUNCT
bjp-62725	122	5	a	a	DET
bjp-62725	122	6	,	,	PUNCT
bjp-62725	122	7	b	b	NOUN
bjp-62725	122	8	,	,	PUNCT
bjp-62725	122	9	c	c	NOUN
bjp-62725	122	10	,	,	PUNCT
bjp-62725	122	11	and	and	CCONJ
bjp-62725	122	12	d	d	X
bjp-62725	122	13	)	)	PUNCT
bjp-62725	122	14	indicate	indicate	VERB
bjp-62725	122	15	the	the	DET
bjp-62725	122	16	outcomes	outcome	NOUN
bjp-62725	122	17	of	of	ADP
bjp-62725	122	18	a	a	DET
bjp-62725	122	19	typical	typical	ADJ
bjp-62725	122	20	experiment	experiment	NOUN
bjp-62725	122	21	,	,	PUNCT
bjp-62725	122	22	whereas	whereas	SCONJ
bjp-62725	122	23	the	the	DET
bjp-62725	122	24	data	datum	NOUN
bjp-62725	122	25	in	in	ADP
bjp-62725	122	26	(	(	PUNCT
bjp-62725	122	27	d	d	NOUN
bjp-62725	122	28	)	)	PUNCT
bjp-62725	122	29	represent	represent	VERB
bjp-62725	122	30	mean	mean	ADJ
bjp-62725	122	31	values	value	NOUN
bjp-62725	122	32	with	with	ADP
bjp-62725	122	33	standard	standard	ADJ
bjp-62725	122	34	deviation	deviation	NOUN
bjp-62725	122	35	.	.	PUNCT
bjp-62725	123	1	*	*	PUNCT
bjp-62725	123	2	p<0.05	p<0.05	NOUN
bjp-62725	123	3	b	b	ADP
bjp-62725	123	4	a	a	DET
bjp-62725	123	5	figure	figure	NOUN
bjp-62725	123	6	4	4	NUM
bjp-62725	123	7	:	:	PUNCT
bjp-62725	123	8	colchicine	colchicine	NOUN
bjp-62725	123	9	cause	cause	VERB
bjp-62725	123	10	regulating	regulate	VERB
bjp-62725	123	11	β	β	NOUN
bjp-62725	123	12	-	-	ADJ
bjp-62725	123	13	catenin	catenin	ADJ
bjp-62725	123	14	expression	expression	NOUN
bjp-62725	123	15	via	via	ADP
bjp-62725	123	16	phosphorylation	phosphorylation	NOUN
bjp-62725	123	17	of	of	ADP
bjp-62725	123	18	gsk-3αβ	gsk-3αβ	NOUN
bjp-62725	123	19	and	and	CCONJ
bjp-62725	123	20	modulating	modulate	VERB
bjp-62725	123	21	nf	nf	ADJ
bjp-62725	123	22	-	-	PUNCT
bjp-62725	123	23	κb	κb	NOUN
bjp-62725	123	24	pathway	pathway	NOUN
bjp-62725	123	25	.	.	PUNCT
bjp-62725	124	1	(	(	PUNCT
bjp-62725	124	2	a	a	PRON
bjp-62725	124	3	and	and	CCONJ
bjp-62725	124	4	b	b	NOUN
bjp-62725	124	5	)	)	PUNCT
bjp-62725	124	6	chondrocytes	chondrocyte	NOUN
bjp-62725	124	7	were	be	AUX
bjp-62725	124	8	either	either	CCONJ
bjp-62725	124	9	left	leave	VERB
bjp-62725	124	10	untreated	untreated	ADJ
bjp-62725	124	11	or	or	CCONJ
bjp-62725	124	12	subjected	subject	VERB
bjp-62725	124	13	to	to	ADP
bjp-62725	124	14	a	a	DET
bjp-62725	124	15	variety	variety	NOUN
bjp-62725	124	16	of	of	ADP
bjp-62725	124	17	colchicine	colchicine	PROPN
bjp-62725	124	18	treatments	treatment	NOUN
bjp-62725	124	19	for	for	ADP
bjp-62725	124	20	24	24	NUM
bjp-62725	124	21	hours	hour	NOUN
bjp-62725	124	22	(	(	PUNCT
bjp-62725	124	23	a	a	NOUN
bjp-62725	124	24	)	)	PUNCT
bjp-62725	124	25	or	or	CCONJ
bjp-62725	124	26	for	for	ADP
bjp-62725	124	27	the	the	DET
bjp-62725	124	28	given	give	VERB
bjp-62725	124	29	amounts	amount	NOUN
bjp-62725	124	30	of	of	ADP
bjp-62725	124	31	time	time	NOUN
bjp-62725	124	32	(	(	PUNCT
bjp-62725	124	33	1	1	NUM
bjp-62725	124	34	μm	μm	NUM
bjp-62725	124	35	colchicine	colchicine	NOUN
bjp-62725	124	36	)	)	PUNCT
bjp-62725	124	37	(	(	PUNCT
bjp-62725	124	38	b	b	NOUN
bjp-62725	124	39	)	)	PUNCT
bjp-62725	124	40	.	.	PUNCT
bjp-62725	125	1	western	western	ADJ
bjp-62725	125	2	blot	blot	NOUN
bjp-62725	125	3	analysis	analysis	NOUN
bjp-62725	125	4	was	be	AUX
bjp-62725	125	5	used	use	VERB
bjp-62725	125	6	to	to	PART
bjp-62725	125	7	determine	determine	VERB
bjp-62725	125	8	the	the	DET
bjp-62725	125	9	expression	expression	NOUN
bjp-62725	125	10	levels	level	NOUN
bjp-62725	125	11	of	of	ADP
bjp-62725	125	12	β	β	NOUN
bjp-62725	125	13	-	-	ADJ
bjp-62725	125	14	catenin	catenin	ADJ
bjp-62725	125	15	,	,	PUNCT
bjp-62725	125	16	pgsk-3αβ	pgsk-3αβ	NOUN
bjp-62725	125	17	(	(	PUNCT
bjp-62725	125	18	ser9/21	ser9/21	NOUN
bjp-62725	125	19	)	)	PUNCT
bjp-62725	125	20	,	,	PUNCT
bjp-62725	125	21	pgsk-3αβ	pgsk-3αβ	NOUN
bjp-62725	125	22	(	(	PUNCT
bjp-62725	125	23	tyr216/279	tyr216/279	NOUN
bjp-62725	125	24	)	)	PUNCT
bjp-62725	125	25	,	,	PUNCT
bjp-62725	125	26	piκbα	piκbα	NOUN
bjp-62725	125	27	,	,	PUNCT
bjp-62725	125	28	iκbα	iκbα	NOUN
bjp-62725	125	29	,	,	PUNCT
bjp-62725	125	30	and	and	CCONJ
bjp-62725	125	31	glyceraldehyde-3	glyceraldehyde-3	VERB
bjp-62725	125	32	-	-	ADJ
bjp-62725	125	33	phosphate	phosphate	ADJ
bjp-62725	125	34	dehydrogenase	dehydrogenase	NOUN
bjp-62725	125	35	(	(	PUNCT
bjp-62725	125	36	gapdh	gapdh	NOUN
bjp-62725	125	37	)	)	PUNCT
bjp-62725	125	38	.	.	PUNCT
bjp-62725	126	1	gapdh	gapdh	NOUN
bjp-62725	126	2	was	be	AUX
bjp-62725	126	3	used	use	VERB
bjp-62725	126	4	as	as	ADP
bjp-62725	126	5	a	a	DET
bjp-62725	126	6	loading	loading	NOUN
bjp-62725	126	7	control	control	NOUN
bjp-62725	126	8	.	.	PUNCT
bjp-62725	127	1	the	the	DET
bjp-62725	127	2	findings	finding	NOUN
bjp-62725	127	3	of	of	ADP
bjp-62725	127	4	an	an	DET
bjp-62725	127	5	average	average	ADJ
bjp-62725	127	6	experiment	experiment	NOUN
bjp-62725	127	7	or	or	CCONJ
bjp-62725	127	8	the	the	DET
bjp-62725	127	9	mean	mean	ADJ
bjp-62725	127	10	values	value	NOUN
bjp-62725	127	11	plus	plus	CCONJ
bjp-62725	127	12	standard	standard	ADJ
bjp-62725	127	13	deviation	deviation	NOUN
bjp-62725	127	14	from	from	ADP
bjp-62725	127	15	at	at	ADV
bjp-62725	127	16	least	least	ADV
bjp-62725	127	17	four	four	NUM
bjp-62725	127	18	different	different	ADJ
bjp-62725	127	19	experiments	experiment	NOUN
bjp-62725	127	20	are	be	AUX
bjp-62725	127	21	represented	represent	VERB
bjp-62725	127	22	by	by	ADP
bjp-62725	127	23	the	the	DET
bjp-62725	127	24	data	data	PROPN
bjp-62725	127	25	bangladesh	bangladesh	PROPN
bjp-62725	127	26	j	j	PROPN
bjp-62725	127	27	pharmacol	pharmacol	PROPN
bjp-62725	127	28	2023	2023	NUM
bjp-62725	127	29	;	;	PUNCT
bjp-62725	127	30	18	18	NUM
bjp-62725	127	31	:	:	SYM
bjp-62725	127	32	8	8	NUM
bjp-62725	127	33	-	-	SYM
bjp-62725	127	34	16	16	NUM
bjp-62725	127	35	13	13	NUM
bjp-62725	127	36	study	study	NOUN
bjp-62725	127	37	.	.	PUNCT
bjp-62725	128	1	microtubule	microtubule	NOUN
bjp-62725	128	2	depolymerization	depolymerization	NOUN
bjp-62725	128	3	caused	cause	VERB
bjp-62725	128	4	by	by	ADP
bjp-62725	128	5	kif18a	kif18a	NOUN
bjp-62725	128	6	activation	activation	NOUN
bjp-62725	128	7	can	can	AUX
bjp-62725	128	8	induce	induce	VERB
bjp-62725	128	9	skeletal	skeletal	ADJ
bjp-62725	128	10	destruction	destruction	NOUN
bjp-62725	128	11	of	of	ADP
bjp-62725	128	12	cells	cell	NOUN
bjp-62725	128	13	and	and	CCONJ
bjp-62725	128	14	inhibit	inhibit	VERB
bjp-62725	128	15	chondrocyte	chondrocyte	NOUN
bjp-62725	128	16	proliferation	proliferation	NOUN
bjp-62725	128	17	(	(	PUNCT
bjp-62725	128	18	sun	sun	NOUN
bjp-62725	128	19	et	et	PROPN
bjp-62725	128	20	al	al	PROPN
bjp-62725	128	21	.	.	PROPN
bjp-62725	128	22	,	,	PUNCT
bjp-62725	128	23	2020	2020	NUM
bjp-62725	128	24	)	)	PUNCT
bjp-62725	128	25	.	.	PUNCT
bjp-62725	129	1	those	those	PRON
bjp-62725	129	2	were	be	AUX
bjp-62725	129	3	the	the	DET
bjp-62725	129	4	results	result	NOUN
bjp-62725	129	5	of	of	ADP
bjp-62725	129	6	the	the	DET
bjp-62725	129	7	inhibition	inhibition	NOUN
bjp-62725	129	8	of	of	ADP
bjp-62725	129	9	tubulin	tubulin	NOUN
bjp-62725	129	10	polymerization	polymerization	NOUN
bjp-62725	129	11	and	and	CCONJ
bjp-62725	129	12	microtubule	microtubule	NOUN
bjp-62725	129	13	depolymerization	depolymerization	NOUN
bjp-62725	129	14	suggests	suggest	VERB
bjp-62725	129	15	that	that	SCONJ
bjp-62725	129	16	it	it	PRON
bjp-62725	129	17	inhibits	inhibit	VERB
bjp-62725	129	18	the	the	DET
bjp-62725	129	19	differentiation	differentiation	NOUN
bjp-62725	129	20	of	of	ADP
bjp-62725	129	21	chondrocytes	chondrocyte	NOUN
bjp-62725	129	22	.	.	PUNCT
bjp-62725	130	1	here	here	ADV
bjp-62725	130	2	,	,	PUNCT
bjp-62725	130	3	it	it	PRON
bjp-62725	130	4	was	be	AUX
bjp-62725	130	5	demonstrated	demonstrate	VERB
bjp-62725	130	6	how	how	SCONJ
bjp-62725	130	7	colchicine	colchicine	PROPN
bjp-62725	130	8	reduced	reduce	VERB
bjp-62725	130	9	chondrocyte	chondrocyte	NOUN
bjp-62725	130	10	differentiation	differentiation	NOUN
bjp-62725	130	11	by	by	ADP
bjp-62725	130	12	inducing	induce	VERB
bjp-62725	130	13	β	β	NOUN
bjp-62725	130	14	-	-	ADJ
bjp-62725	130	15	catenin	catenin	ADJ
bjp-62725	130	16	expression	expression	NOUN
bjp-62725	130	17	at	at	ADP
bjp-62725	130	18	both	both	CCONJ
bjp-62725	130	19	the	the	DET
bjp-62725	130	20	protein	protein	NOUN
bjp-62725	130	21	and	and	CCONJ
bjp-62725	130	22	mrna	mrna	PROPN
bjp-62725	130	23	levels	level	NOUN
bjp-62725	130	24	.	.	PUNCT
bjp-62725	131	1	furthermore	furthermore	ADV
bjp-62725	131	2	,	,	PUNCT
bjp-62725	131	3	colchicine	colchicine	PROPN
bjp-62725	131	4	's	's	PART
bjp-62725	131	5	suppression	suppression	NOUN
bjp-62725	131	6	of	of	ADP
bjp-62725	131	7	chondrocyte	chondrocyte	NOUN
bjp-62725	131	8	microtubule	microtubule	NOUN
bjp-62725	131	9	polymerization	polymerization	NOUN
bjp-62725	131	10	increased	increase	VERB
bjp-62725	131	11	in	in	ADP
bjp-62725	131	12	β	β	NOUN
bjp-62725	131	13	-	-	ADJ
bjp-62725	131	14	catenin	catenin	ADJ
bjp-62725	131	15	expression	expression	NOUN
bjp-62725	131	16	.	.	PUNCT
bjp-62725	132	1	the	the	DET
bjp-62725	132	2	results	result	NOUN
bjp-62725	132	3	of	of	ADP
bjp-62725	132	4	the	the	DET
bjp-62725	132	5	current	current	ADJ
bjp-62725	132	6	investigation	investigation	NOUN
bjp-62725	132	7	suggested	suggest	VERB
bjp-62725	132	8	that	that	SCONJ
bjp-62725	132	9	colchicine	colchicine	PROPN
bjp-62725	132	10	controls	control	VERB
bjp-62725	132	11	the	the	DET
bjp-62725	132	12	wnt	wnt	NOUN
bjp-62725	132	13	/	/	SYM
bjp-62725	132	14	β	β	NOUN
bjp-62725	132	15	-	-	ADJ
bjp-62725	132	16	catenin	catenin	ADJ
bjp-62725	132	17	pathway	pathway	NOUN
bjp-62725	132	18	,	,	PUNCT
bjp-62725	132	19	which	which	PRON
bjp-62725	132	20	has	have	AUX
bjp-62725	132	21	been	be	AUX
bjp-62725	132	22	proven	prove	VERB
bjp-62725	132	23	to	to	PART
bjp-62725	132	24	regulate	regulate	VERB
bjp-62725	132	25	chondrocyte	chondrocyte	NOUN
bjp-62725	132	26	dedifferentiation	dedifferentiation	NOUN
bjp-62725	132	27	.	.	PUNCT
bjp-62725	133	1	according	accord	VERB
bjp-62725	133	2	to	to	ADP
bjp-62725	133	3	earlier	early	ADJ
bjp-62725	133	4	research	research	NOUN
bjp-62725	133	5	that	that	PRON
bjp-62725	133	6	supports	support	VERB
bjp-62725	133	7	other	other	ADJ
bjp-62725	133	8	findings	finding	NOUN
bjp-62725	133	9	,	,	PUNCT
bjp-62725	133	10	simvastatin	simvastatin	PROPN
bjp-62725	133	11	causes	cause	VERB
bjp-62725	133	12	differentiation	differentiation	NOUN
bjp-62725	133	13	via	via	ADP
bjp-62725	133	14	activating	activate	VERB
bjp-62725	133	15	the	the	DET
bjp-62725	133	16	wnt	wnt	NOUN
bjp-62725	133	17	/	/	SYM
bjp-62725	133	18	β	β	NOUN
bjp-62725	133	19	-	-	ADJ
bjp-62725	133	20	catenin	catenin	ADJ
bjp-62725	133	21	pathway	pathway	NOUN
bjp-62725	133	22	(	(	PUNCT
bjp-62725	133	23	yu	yu	PROPN
bjp-62725	133	24	et	et	PROPN
bjp-62725	133	25	al	al	PROPN
bjp-62725	133	26	.	.	PROPN
bjp-62725	133	27	,	,	PUNCT
bjp-62725	133	28	2019	2019	NUM
bjp-62725	133	29	)	)	PUNCT
bjp-62725	133	30	.	.	PUNCT
bjp-62725	134	1	it	it	PRON
bjp-62725	134	2	may	may	AUX
bjp-62725	134	3	be	be	AUX
bjp-62725	134	4	helpful	helpful	ADJ
bjp-62725	134	5	for	for	ADP
bjp-62725	134	6	cartilage	cartilage	NOUN
bjp-62725	134	7	treatment	treatment	NOUN
bjp-62725	134	8	to	to	PART
bjp-62725	134	9	understand	understand	VERB
bjp-62725	134	10	the	the	DET
bjp-62725	134	11	mechanism	mechanism	NOUN
bjp-62725	134	12	of	of	ADP
bjp-62725	134	13	action	action	NOUN
bjp-62725	134	14	of	of	ADP
bjp-62725	134	15	the	the	DET
bjp-62725	134	16	inflammatory	inflammatory	ADJ
bjp-62725	134	17	response	response	NOUN
bjp-62725	134	18	,	,	PUNCT
bjp-62725	134	19	which	which	PRON
bjp-62725	134	20	is	be	AUX
bjp-62725	134	21	a	a	DET
bjp-62725	134	22	significant	significant	ADJ
bjp-62725	134	23	contributor	contributor	NOUN
bjp-62725	134	24	to	to	ADP
bjp-62725	134	25	cartilage	cartilage	NOUN
bjp-62725	134	26	breakdown	breakdown	NOUN
bjp-62725	134	27	in	in	ADP
bjp-62725	134	28	osteoarthritis	osteoarthritis	NOUN
bjp-62725	134	29	.	.	PUNCT
bjp-62725	135	1	additionally	additionally	ADV
bjp-62725	135	2	,	,	PUNCT
bjp-62725	135	3	cox-2	cox-2	NOUN
bjp-62725	135	4	,	,	PUNCT
bjp-62725	135	5	a	a	DET
bjp-62725	135	6	crucial	crucial	ADJ
bjp-62725	135	7	regulator	regulator	NOUN
bjp-62725	135	8	of	of	ADP
bjp-62725	135	9	cartilage	cartilage	NOUN
bjp-62725	135	10	inflammation	inflammation	NOUN
bjp-62725	135	11	,	,	PUNCT
bjp-62725	135	12	was	be	AUX
bjp-62725	135	13	verified	verify	VERB
bjp-62725	135	14	by	by	ADP
bjp-62725	135	15	recent	recent	ADJ
bjp-62725	135	16	investigations	investigation	NOUN
bjp-62725	135	17	(	(	PUNCT
bjp-62725	135	18	han	han	PROPN
bjp-62725	135	19	and	and	CCONJ
bjp-62725	135	20	kim	kim	PROPN
bjp-62725	135	21	,	,	PUNCT
bjp-62725	135	22	2018	2018	NUM
bjp-62725	135	23	;	;	PUNCT
bjp-62725	135	24	yu	yu	PROPN
bjp-62725	135	25	et	et	PROPN
bjp-62725	135	26	al	al	PROPN
bjp-62725	135	27	.	.	PROPN
bjp-62725	135	28	,	,	PUNCT
bjp-62725	135	29	2019	2019	NUM
bjp-62725	135	30	)	)	PUNCT
bjp-62725	135	31	.	.	PUNCT
bjp-62725	136	1	these	these	DET
bjp-62725	136	2	findings	finding	NOUN
bjp-62725	136	3	suggest	suggest	VERB
bjp-62725	136	4	that	that	SCONJ
bjp-62725	136	5	controlling	control	VERB
bjp-62725	136	6	microtubule	microtubule	NOUN
bjp-62725	136	7	production	production	NOUN
bjp-62725	136	8	and	and	CCONJ
bjp-62725	136	9	cox-2	cox-2	ADJ
bjp-62725	137	1	expression	expression	NOUN
bjp-62725	138	1	in	in	ADP
bjp-62725	138	2	chondrocytes	chondrocyte	NOUN
bjp-62725	139	1	may	may	AUX
bjp-62725	139	2	be	be	AUX
bjp-62725	139	3	able	able	ADJ
bjp-62725	139	4	to	to	PART
bjp-62725	139	5	prevent	prevent	VERB
bjp-62725	139	6	cartilage	cartilage	NOUN
bjp-62725	139	7	degeneration	degeneration	NOUN
bjp-62725	139	8	.	.	PUNCT
bjp-62725	140	1	many	many	ADJ
bjp-62725	140	2	cytokines	cytokine	NOUN
bjp-62725	140	3	and	and	CCONJ
bjp-62725	140	4	inflammatory	inflammatory	ADJ
bjp-62725	140	5	response	response	NOUN
bjp-62725	140	6	mediators	mediator	NOUN
bjp-62725	140	7	produced	produce	VERB
bjp-62725	140	8	by	by	ADP
bjp-62725	140	9	the	the	DET
bjp-62725	140	10	activation	activation	NOUN
bjp-62725	140	11	of	of	ADP
bjp-62725	140	12	immune	immune	ADJ
bjp-62725	140	13	cells	cell	NOUN
bjp-62725	140	14	are	be	AUX
bjp-62725	140	15	one	one	NUM
bjp-62725	140	16	of	of	ADP
bjp-62725	140	17	the	the	DET
bjp-62725	140	18	common	common	ADJ
bjp-62725	140	19	pathogeneses	pathogenese	NOUN
bjp-62725	140	20	of	of	ADP
bjp-62725	140	21	rheumatoid	rheumatoid	NOUN
bjp-62725	140	22	and	and	CCONJ
bjp-62725	140	23	degenerative	degenerative	ADJ
bjp-62725	140	24	arthritis	arthritis	NOUN
bjp-62725	140	25	(	(	PUNCT
bjp-62725	140	26	shah	shah	NOUN
bjp-62725	140	27	and	and	CCONJ
bjp-62725	140	28	kim	kim	PROPN
bjp-62725	140	29	,	,	PUNCT
bjp-62725	140	30	2022	2022	NUM
bjp-62725	140	31	)	)	PUNCT
bjp-62725	140	32	.	.	PUNCT
bjp-62725	141	1	the	the	DET
bjp-62725	141	2	activity	activity	NOUN
bjp-62725	141	3	of	of	ADP
bjp-62725	141	4	nf	nf	NOUN
bjp-62725	141	5	a	a	DET
bjp-62725	141	6	figure	figure	NOUN
bjp-62725	141	7	5	5	NUM
bjp-62725	141	8	:	:	PUNCT
bjp-62725	141	9	colchicine	colchicine	PROPN
bjp-62725	141	10	causes	cause	VERB
bjp-62725	141	11	chondrocyte	chondrocyte	ADJ
bjp-62725	141	12	de	de	NOUN
bjp-62725	141	13	-	-	NOUN
bjp-62725	141	14	differentiation	differentiation	NOUN
bjp-62725	141	15	via	via	ADP
bjp-62725	141	16	regulating	regulate	VERB
bjp-62725	141	17	the	the	DET
bjp-62725	141	18	β	β	NOUN
bjp-62725	141	19	-	-	ADJ
bjp-62725	141	20	catenin	catenin	ADJ
bjp-62725	141	21	pathway	pathway	NOUN
bjp-62725	141	22	(	(	PUNCT
bjp-62725	141	23	a	a	X
bjp-62725	141	24	)	)	PUNCT
bjp-62725	141	25	chondrocytes	chondrocyte	NOUN
bjp-62725	141	26	were	be	AUX
bjp-62725	141	27	treated	treat	VERB
bjp-62725	141	28	with	with	ADP
bjp-62725	141	29	20	20	NUM
bjp-62725	141	30	μm	μm	NOUN
bjp-62725	141	31	mg132	mg132	PROPN
bjp-62725	141	32	for	for	ADP
bjp-62725	141	33	12	12	NUM
bjp-62725	141	34	hours	hour	NOUN
bjp-62725	141	35	before	before	ADP
bjp-62725	141	36	being	be	AUX
bjp-62725	141	37	exposed	expose	VERB
bjp-62725	141	38	to	to	ADP
bjp-62725	141	39	1	1	NUM
bjp-62725	141	40	μm	μm	NOUN
bjp-62725	141	41	colchicine	colchicine	NOUN
bjp-62725	141	42	for	for	ADP
bjp-62725	141	43	24	24	NUM
bjp-62725	141	44	hours	hour	NOUN
bjp-62725	141	45	,	,	PUNCT
bjp-62725	141	46	or	or	CCONJ
bjp-62725	141	47	they	they	PRON
bjp-62725	141	48	were	be	AUX
bjp-62725	141	49	transfected	transfecte	VERB
bjp-62725	141	50	for	for	ADP
bjp-62725	141	51	12	12	NUM
bjp-62725	141	52	hours	hour	NOUN
bjp-62725	141	53	with	with	ADP
bjp-62725	141	54	either	either	CCONJ
bjp-62725	141	55	an	an	DET
bjp-62725	141	56	empty	empty	ADJ
bjp-62725	141	57	vector	vector	NOUN
bjp-62725	141	58	or	or	CCONJ
bjp-62725	141	59	0.1	0.1	NUM
bjp-62725	141	60	μm	μm	NOUN
bjp-62725	141	61	sir	sir	NOUN
bjp-62725	141	62	β	β	NOUN
bjp-62725	141	63	-	-	NOUN
bjp-62725	141	64	catenin	catenin	ADJ
bjp-62725	141	65	.	.	PUNCT
bjp-62725	142	1	western	western	ADJ
bjp-62725	142	2	blot	blot	NOUN
bjp-62725	142	3	analysis	analysis	NOUN
bjp-62725	142	4	was	be	AUX
bjp-62725	142	5	used	use	VERB
bjp-62725	142	6	to	to	PART
bjp-62725	142	7	find	find	VERB
bjp-62725	142	8	the	the	DET
bjp-62725	142	9	expression	expression	NOUN
bjp-62725	142	10	of	of	ADP
bjp-62725	142	11	type	type	NOUN
bjp-62725	142	12	ii	ii	PROPN
bjp-62725	142	13	collagen	collagen	PROPN
bjp-62725	142	14	,	,	PUNCT
bjp-62725	142	15	β	β	NOUN
bjp-62725	142	16	-	-	ADJ
bjp-62725	142	17	catenin	catenin	ADJ
bjp-62725	142	18	,	,	PUNCT
bjp-62725	142	19	pgsk3	pgsk3	NOUN
bjp-62725	142	20	(	(	PUNCT
bjp-62725	142	21	ser9/21	ser9/21	NOUN
bjp-62725	142	22	)	)	PUNCT
bjp-62725	142	23	,	,	PUNCT
bjp-62725	142	24	pgsk-3	pgsk-3	PROPN
bjp-62725	142	25	(	(	PUNCT
bjp-62725	142	26	tyr216/279	tyr216/279	NOUN
bjp-62725	142	27	)	)	PUNCT
bjp-62725	142	28	,	,	PUNCT
bjp-62725	142	29	and	and	CCONJ
bjp-62725	142	30	gapdh	gapdh	NOUN
bjp-62725	142	31	.	.	PUNCT
bjp-62725	143	1	gapdh	gapdh	NOUN
bjp-62725	143	2	was	be	AUX
bjp-62725	143	3	used	use	VERB
bjp-62725	143	4	as	as	ADP
bjp-62725	143	5	a	a	DET
bjp-62725	143	6	loading	loading	NOUN
bjp-62725	143	7	control	control	NOUN
bjp-62725	143	8	.	.	PUNCT
bjp-62725	144	1	(	(	PUNCT
bjp-62725	144	2	b	b	X
bjp-62725	144	3	)	)	PUNCT
bjp-62725	144	4	chondrocytes	chondrocyte	NOUN
bjp-62725	144	5	were	be	AUX
bjp-62725	144	6	subjected	subject	VERB
bjp-62725	144	7	to	to	ADP
bjp-62725	144	8	1	1	NUM
bjp-62725	144	9	mm	mm	PROPN
bjp-62725	144	10	colchicine	colchicine	NOUN
bjp-62725	144	11	for	for	ADP
bjp-62725	144	12	24	24	NUM
bjp-62725	144	13	hours	hour	NOUN
bjp-62725	144	14	after	after	ADP
bjp-62725	144	15	being	be	AUX
bjp-62725	144	16	left	leave	VERB
bjp-62725	144	17	untreated	untreated	ADJ
bjp-62725	144	18	or	or	CCONJ
bjp-62725	144	19	treated	treat	VERB
bjp-62725	144	20	for	for	ADP
bjp-62725	144	21	3	3	NUM
bjp-62725	144	22	hours	hour	NOUN
bjp-62725	144	23	with	with	ADP
bjp-62725	144	24	5	5	NUM
bjp-62725	144	25	mm	mm	NUM
bjp-62725	144	26	tax	tax	NOUN
bjp-62725	144	27	.	.	PUNCT
bjp-62725	145	1	western	western	ADJ
bjp-62725	145	2	blot	blot	NOUN
bjp-62725	145	3	analysis	analysis	NOUN
bjp-62725	145	4	was	be	AUX
bjp-62725	145	5	used	use	VERB
bjp-62725	145	6	to	to	PART
bjp-62725	145	7	find	find	VERB
bjp-62725	145	8	expression	expression	NOUN
bjp-62725	145	9	of	of	ADP
bjp-62725	145	10	pgsk-3	pgsk-3	PROPN
bjp-62725	145	11	(	(	PUNCT
bjp-62725	145	12	ser9/21	ser9/21	NOUN
bjp-62725	145	13	)	)	PUNCT
bjp-62725	145	14	,	,	PUNCT
bjp-62725	145	15	pgsk	pgsk	NOUN
bjp-62725	145	16	-3	-3	INTJ
bjp-62725	145	17	(	(	PUNCT
bjp-62725	145	18	tyr216/279	tyr216/279	NOUN
bjp-62725	145	19	)	)	PUNCT
bjp-62725	145	20	,	,	PUNCT
bjp-62725	145	21	and	and	CCONJ
bjp-62725	145	22	gapdh	gapdh	NOUN
bjp-62725	145	23	.	.	PUNCT
bjp-62725	146	1	we	we	PRON
bjp-62725	146	2	used	use	VERB
bjp-62725	146	3	gapdh	gapdh	NOUN
bjp-62725	146	4	as	as	ADP
bjp-62725	146	5	a	a	DET
bjp-62725	146	6	loading	loading	NOUN
bjp-62725	146	7	control	control	NOUN
bjp-62725	146	8	.	.	PUNCT
bjp-62725	147	1	(	(	PUNCT
bjp-62725	147	2	c	c	X
bjp-62725	147	3	)	)	PUNCT
bjp-62725	147	4	chondrocytes	chondrocyte	NOUN
bjp-62725	147	5	were	be	AUX
bjp-62725	147	6	transfected	transfecte	VERB
bjp-62725	147	7	for	for	ADP
bjp-62725	147	8	12	12	NUM
bjp-62725	147	9	hours	hour	NOUN
bjp-62725	147	10	with	with	ADP
bjp-62725	147	11	either	either	CCONJ
bjp-62725	147	12	an	an	DET
bjp-62725	147	13	empty	empty	ADJ
bjp-62725	147	14	vector	vector	NOUN
bjp-62725	147	15	or	or	CCONJ
bjp-62725	147	16	0.1	0.1	NUM
bjp-62725	147	17	μm	μm	NOUN
bjp-62725	147	18	sir	sir	NOUN
bjp-62725	147	19	β	β	NOUN
bjp-62725	147	20	-	-	NOUN
bjp-62725	147	21	catenin	catenin	NOUN
bjp-62725	147	22	before	before	ADP
bjp-62725	147	23	being	be	AUX
bjp-62725	147	24	subjected	subject	VERB
bjp-62725	147	25	for	for	ADP
bjp-62725	147	26	24	24	NUM
bjp-62725	147	27	hours	hour	NOUN
bjp-62725	147	28	to	to	ADP
bjp-62725	147	29	1	1	NUM
bjp-62725	147	30	μm	μm	NUM
bjp-62725	147	31	colchicine	colchicine	NOUN
bjp-62725	147	32	.	.	PUNCT
bjp-62725	148	1	using	use	VERB
bjp-62725	148	2	immunofluorescence	immunofluorescence	NOUN
bjp-62725	148	3	labeling	labeling	NOUN
bjp-62725	148	4	,	,	PUNCT
bjp-62725	148	5	it	it	PRON
bjp-62725	148	6	was	be	AUX
bjp-62725	148	7	possible	possible	ADJ
bjp-62725	148	8	to	to	PART
bjp-62725	148	9	measure	measure	VERB
bjp-62725	148	10	the	the	DET
bjp-62725	148	11	expression	expression	NOUN
bjp-62725	148	12	of	of	ADP
bjp-62725	148	13	type	type	NOUN
bjp-62725	148	14	ii	ii	PROPN
bjp-62725	148	15	collagen	collagen	NOUN
bjp-62725	148	16	and	and	CCONJ
bjp-62725	148	17	β	β	NOUN
bjp-62725	148	18	catenin	catenin	NOUN
bjp-62725	148	19	.	.	PUNCT
bjp-62725	149	1	cells	cell	NOUN
bjp-62725	149	2	were	be	AUX
bjp-62725	149	3	labeled	label	VERB
bjp-62725	149	4	with	with	ADP
bjp-62725	149	5	a	a	DET
bjp-62725	149	6	particular	particular	ADJ
bjp-62725	149	7	antibody	antibody	NOUN
bjp-62725	149	8	(	(	PUNCT
bjp-62725	149	9	red	red	ADJ
bjp-62725	149	10	or	or	CCONJ
bjp-62725	149	11	green	green	ADJ
bjp-62725	149	12	)	)	PUNCT
bjp-62725	149	13	and	and	CCONJ
bjp-62725	149	14	dapi	dapi	ADJ
bjp-62725	149	15	for	for	ADP
bjp-62725	149	16	nuclear	nuclear	ADJ
bjp-62725	149	17	staining	stain	VERB
bjp-62725	149	18	(	(	PUNCT
bjp-62725	149	19	blue	blue	ADJ
bjp-62725	149	20	)	)	PUNCT
bjp-62725	149	21	.	.	PUNCT
bjp-62725	150	1	magnification	magnification	NOUN
bjp-62725	150	2	:	:	PUNCT
bjp-62725	151	1	x400	x400	PROPN
bjp-62725	151	2	b	b	PROPN
bjp-62725	151	3	a	a	DET
bjp-62725	151	4	b	b	PROPN
bjp-62725	151	5	figure	figure	NOUN
bjp-62725	151	6	6	6	NUM
bjp-62725	151	7	:	:	PUNCT
bjp-62725	151	8	colchicine	colchicine	PROPN
bjp-62725	151	9	causes	cause	VERB
bjp-62725	151	10	inflammation	inflammation	NOUN
bjp-62725	151	11	via	via	ADP
bjp-62725	151	12	nf	nf	NOUN
bjp-62725	151	13	-	-	PUNCT
bjp-62725	151	14	κb	κb	NOUN
bjp-62725	151	15	pathway	pathway	NOUN
bjp-62725	151	16	in	in	ADP
bjp-62725	151	17	articular	articular	ADJ
bjp-62725	151	18	chondrocytes	chondrocyte	NOUN
bjp-62725	151	19	chondrocytes	chondrocyte	NOUN
bjp-62725	151	20	were	be	AUX
bjp-62725	151	21	either	either	CCONJ
bjp-62725	151	22	left	leave	VERB
bjp-62725	151	23	untreated	untreated	ADJ
bjp-62725	151	24	or	or	CCONJ
bjp-62725	151	25	given	give	VERB
bjp-62725	151	26	20	20	NUM
bjp-62725	151	27	μm	μm	NUM
bjp-62725	151	28	bms	bms	NOUN
bjp-62725	151	29	for	for	ADP
bjp-62725	151	30	3	3	NUM
bjp-62725	151	31	hours	hour	NOUN
bjp-62725	151	32	before	before	ADP
bjp-62725	151	33	being	be	AUX
bjp-62725	151	34	subjected	subject	VERB
bjp-62725	151	35	to	to	ADP
bjp-62725	151	36	1	1	NUM
bjp-62725	151	37	μm	μm	NOUN
bjp-62725	151	38	colchicine	colchicine	NOUN
bjp-62725	151	39	for	for	ADP
bjp-62725	151	40	24	24	NUM
bjp-62725	151	41	hours	hour	NOUN
bjp-62725	151	42	(	(	PUNCT
bjp-62725	151	43	figure	figure	VERB
bjp-62725	151	44	a	a	DET
bjp-62725	151	45	)	)	PUNCT
bjp-62725	151	46	.	.	PUNCT
bjp-62725	152	1	western	western	ADJ
bjp-62725	152	2	blot	blot	NOUN
bjp-62725	152	3	analysis	analysis	NOUN
bjp-62725	152	4	was	be	AUX
bjp-62725	152	5	used	use	VERB
bjp-62725	152	6	to	to	PART
bjp-62725	152	7	find	find	VERB
bjp-62725	152	8	the	the	DET
bjp-62725	152	9	expression	expression	NOUN
bjp-62725	152	10	of	of	ADP
bjp-62725	152	11	cox-2	cox-2	NOUN
bjp-62725	152	12	,	,	PUNCT
bjp-62725	152	13	piκbα	piκbα	NOUN
bjp-62725	152	14	,	,	PUNCT
bjp-62725	152	15	iκbα	iκbα	NOUN
bjp-62725	152	16	and	and	CCONJ
bjp-62725	152	17	gapdh	gapdh	NOUN
bjp-62725	152	18	.	.	PUNCT
bjp-62725	153	1	gapdh	gapdh	NOUN
bjp-62725	153	2	was	be	AUX
bjp-62725	153	3	used	use	VERB
bjp-62725	153	4	as	as	ADP
bjp-62725	153	5	a	a	DET
bjp-62725	153	6	loading	loading	NOUN
bjp-62725	153	7	control	control	NOUN
bjp-62725	153	8	.	.	PUNCT
bjp-62725	154	1	(	(	PUNCT
bjp-62725	154	2	b	b	X
bjp-62725	154	3	)	)	PUNCT
bjp-62725	154	4	chondrocytes	chondrocyte	NOUN
bjp-62725	154	5	were	be	AUX
bjp-62725	154	6	subjected	subject	VERB
bjp-62725	154	7	to	to	ADP
bjp-62725	154	8	1	1	NUM
bjp-62725	154	9	mm	mm	PROPN
bjp-62725	154	10	colchicine	colchicine	NOUN
bjp-62725	154	11	for	for	ADP
bjp-62725	154	12	24	24	NUM
bjp-62725	154	13	hours	hour	NOUN
bjp-62725	154	14	after	after	ADP
bjp-62725	154	15	being	be	AUX
bjp-62725	154	16	left	leave	VERB
bjp-62725	154	17	untreated	untreated	ADJ
bjp-62725	154	18	or	or	CCONJ
bjp-62725	154	19	treated	treat	VERB
bjp-62725	154	20	for	for	ADP
bjp-62725	154	21	3	3	NUM
bjp-62725	154	22	hours	hour	NOUN
bjp-62725	154	23	with	with	ADP
bjp-62725	154	24	5	5	NUM
bjp-62725	154	25	mm	mm	NUM
bjp-62725	154	26	tax	tax	NOUN
bjp-62725	154	27	.	.	PUNCT
bjp-62725	155	1	western	western	ADJ
bjp-62725	155	2	blot	blot	NOUN
bjp-62725	155	3	analysis	analysis	NOUN
bjp-62725	155	4	was	be	AUX
bjp-62725	155	5	used	use	VERB
bjp-62725	155	6	to	to	PART
bjp-62725	155	7	find	find	VERB
bjp-62725	155	8	the	the	DET
bjp-62725	155	9	expression	expression	NOUN
bjp-62725	155	10	of	of	ADP
bjp-62725	155	11	cox-2	cox-2	NOUN
bjp-62725	155	12	,	,	PUNCT
bjp-62725	155	13	piκbα	piκbα	NOUN
bjp-62725	155	14	,	,	PUNCT
bjp-62725	155	15	iκbα	iκbα	NOUN
bjp-62725	155	16	,	,	PUNCT
bjp-62725	155	17	and	and	CCONJ
bjp-62725	155	18	gapdh	gapdh	NOUN
bjp-62725	155	19	14	14	NUM
bjp-62725	155	20	bangladesh	bangladesh	PROPN
bjp-62725	155	21	j	j	PROPN
bjp-62725	155	22	pharmacol	pharmacol	PROPN
bjp-62725	155	23	2023	2023	NUM
bjp-62725	155	24	;	;	PUNCT
bjp-62725	155	25	18	18	NUM
bjp-62725	155	26	:	:	SYM
bjp-62725	155	27	8	8	NUM
bjp-62725	155	28	-	-	SYM
bjp-62725	155	29	16	16	NUM
bjp-62725	155	30	-κb	-κb	NOUN
bjp-62725	155	31	,	,	PUNCT
bjp-62725	155	32	which	which	PRON
bjp-62725	155	33	is	be	AUX
bjp-62725	155	34	phosphorylated	phosphorylate	VERB
bjp-62725	155	35	by	by	ADP
bjp-62725	155	36	iκb	iκb	NOUN
bjp-62725	155	37	,	,	PUNCT
bjp-62725	155	38	has	have	AUX
bjp-62725	155	39	been	be	AUX
bjp-62725	155	40	linked	link	VERB
bjp-62725	155	41	to	to	ADP
bjp-62725	155	42	the	the	DET
bjp-62725	155	43	etiology	etiology	NOUN
bjp-62725	155	44	of	of	ADP
bjp-62725	155	45	numerous	numerous	ADJ
bjp-62725	155	46	diseases	disease	NOUN
bjp-62725	155	47	(	(	PUNCT
bjp-62725	155	48	zhang	zhang	X
bjp-62725	155	49	et	et	PROPN
bjp-62725	155	50	al	al	PROPN
bjp-62725	155	51	.	.	PROPN
bjp-62725	155	52	,	,	PUNCT
bjp-62725	155	53	2021	2021	NUM
bjp-62725	155	54	)	)	PUNCT
bjp-62725	155	55	.	.	PUNCT
bjp-62725	156	1	additionally	additionally	ADV
bjp-62725	156	2	,	,	PUNCT
bjp-62725	156	3	nf	nf	ADJ
bjp-62725	156	4	-	-	PUNCT
bjp-62725	156	5	κb	κb	PROPN
bjp-62725	156	6	regulates	regulate	VERB
bjp-62725	156	7	inflammatory	inflammatory	ADJ
bjp-62725	156	8	regulators	regulator	NOUN
bjp-62725	156	9	like	like	ADP
bjp-62725	156	10	no	no	INTJ
bjp-62725	156	11	and	and	CCONJ
bjp-62725	156	12	ros	ros	PROPN
bjp-62725	156	13	,	,	PUNCT
bjp-62725	156	14	which	which	PRON
bjp-62725	156	15	promotes	promote	VERB
bjp-62725	156	16	the	the	DET
bjp-62725	156	17	formation	formation	NOUN
bjp-62725	156	18	of	of	ADP
bjp-62725	156	19	matrix	matrix	NOUN
bjp-62725	156	20	metalloproteases	metalloprotease	NOUN
bjp-62725	156	21	and	and	CCONJ
bjp-62725	156	22	inhibits	inhibit	VERB
bjp-62725	156	23	the	the	DET
bjp-62725	156	24	synthesis	synthesis	NOUN
bjp-62725	156	25	of	of	ADP
bjp-62725	156	26	extracellular	extracellular	ADJ
bjp-62725	156	27	matrix	matrix	NOUN
bjp-62725	156	28	.	.	PUNCT
bjp-62725	157	1	according	accord	VERB
bjp-62725	157	2	to	to	ADP
bjp-62725	157	3	several	several	ADJ
bjp-62725	157	4	studies	study	NOUN
bjp-62725	157	5	,	,	PUNCT
bjp-62725	157	6	nfκb	nfκb	NOUN
bjp-62725	157	7	can	can	AUX
bjp-62725	157	8	control	control	VERB
bjp-62725	157	9	how	how	SCONJ
bjp-62725	157	10	matrix	matrix	NOUN
bjp-62725	157	11	metalloproteases	metalloprotease	NOUN
bjp-62725	157	12	are	be	AUX
bjp-62725	157	13	expressed	express	VERB
bjp-62725	157	14	in	in	ADP
bjp-62725	157	15	chondrocytes	chondrocyte	NOUN
bjp-62725	157	16	(	(	PUNCT
bjp-62725	157	17	li	li	PROPN
bjp-62725	157	18	et	et	PROPN
bjp-62725	157	19	al	al	PROPN
bjp-62725	157	20	.	.	PROPN
bjp-62725	157	21	,	,	PUNCT
bjp-62725	157	22	2012	2012	NUM
bjp-62725	157	23	;	;	PUNCT
bjp-62725	157	24	ostojic	ostojic	NOUN
bjp-62725	157	25	et	et	PROPN
bjp-62725	157	26	al	al	PROPN
bjp-62725	157	27	.	.	PROPN
bjp-62725	157	28	,	,	PUNCT
bjp-62725	157	29	2021	2021	NUM
bjp-62725	157	30	)	)	PUNCT
bjp-62725	157	31	.	.	PUNCT
bjp-62725	158	1	the	the	DET
bjp-62725	158	2	nf	nf	ADJ
bjp-62725	158	3	-	-	PUNCT
bjp-62725	158	4	κb	κb	NOUN
bjp-62725	158	5	pathway	pathway	NOUN
bjp-62725	158	6	must	must	AUX
bjp-62725	158	7	therefore	therefore	ADV
bjp-62725	158	8	be	be	AUX
bjp-62725	158	9	modulated	modulate	VERB
bjp-62725	158	10	to	to	PART
bjp-62725	158	11	cure	cure	VERB
bjp-62725	158	12	arthritic	arthritic	ADJ
bjp-62725	158	13	conditions	condition	NOUN
bjp-62725	158	14	like	like	ADP
bjp-62725	158	15	ra	ra	PROPN
bjp-62725	158	16	and	and	CCONJ
bjp-62725	158	17	osteoarthritis	osteoarthritis	NOUN
bjp-62725	158	18	.	.	PUNCT
bjp-62725	159	1	these	these	DET
bjp-62725	159	2	findings	finding	NOUN
bjp-62725	159	3	further	far	ADV
bjp-62725	159	4	supported	support	VERB
bjp-62725	159	5	this	this	DET
bjp-62725	159	6	proposed	propose	VERB
bjp-62725	159	7	mechanism	mechanism	NOUN
bjp-62725	159	8	by	by	ADP
bjp-62725	159	9	showing	show	VERB
bjp-62725	159	10	that	that	SCONJ
bjp-62725	159	11	the	the	DET
bjp-62725	159	12	nf	nf	ADJ
bjp-62725	159	13	-	-	PUNCT
bjp-62725	159	14	κb	κb	NOUN
bjp-62725	159	15	pathway	pathway	NOUN
bjp-62725	159	16	was	be	AUX
bjp-62725	159	17	significantly	significantly	ADV
bjp-62725	159	18	stimulated	stimulate	VERB
bjp-62725	159	19	in	in	ADP
bjp-62725	159	20	colchicine	colchicine	NOUN
bjp-62725	159	21	-	-	PUNCT
bjp-62725	159	22	added	add	VERB
bjp-62725	159	23	cells	cell	NOUN
bjp-62725	159	24	compared	compare	VERB
bjp-62725	159	25	to	to	ADP
bjp-62725	159	26	control	control	NOUN
bjp-62725	159	27	cells	cell	NOUN
bjp-62725	159	28	.	.	PUNCT
bjp-62725	160	1	these	these	DET
bjp-62725	160	2	findings	finding	NOUN
bjp-62725	160	3	showed	show	VERB
bjp-62725	160	4	that	that	SCONJ
bjp-62725	160	5	colchicine	colchicine	PROPN
bjp-62725	160	6	increased	increase	VERB
bjp-62725	160	7	levels	level	NOUN
bjp-62725	160	8	of	of	ADP
bjp-62725	160	9	pro	pro	ADJ
bjp-62725	160	10	-	-	ADJ
bjp-62725	160	11	inflammatory	inflammatory	ADJ
bjp-62725	160	12	mediators	mediator	NOUN
bjp-62725	160	13	,	,	PUNCT
bjp-62725	160	14	which	which	PRON
bjp-62725	160	15	may	may	AUX
bjp-62725	160	16	be	be	AUX
bjp-62725	160	17	extremely	extremely	ADV
bjp-62725	160	18	important	important	ADJ
bjp-62725	160	19	for	for	ADP
bjp-62725	160	20	the	the	DET
bjp-62725	160	21	management	management	NOUN
bjp-62725	160	22	of	of	ADP
bjp-62725	160	23	osteoarthritis	osteoarthritis	NOUN
bjp-62725	160	24	.	.	PUNCT
bjp-62725	161	1	it	it	PRON
bjp-62725	161	2	is	be	AUX
bjp-62725	161	3	proposed	propose	VERB
bjp-62725	161	4	that	that	SCONJ
bjp-62725	161	5	the	the	DET
bjp-62725	161	6	chondrocyte	chondrocyte	PROPN
bjp-62725	161	7	phenotype	phenotype	NOUN
bjp-62725	161	8	is	be	AUX
bjp-62725	161	9	modified	modify	VERB
bjp-62725	161	10	during	during	ADP
bjp-62725	161	11	monolayer	monolayer	NOUN
bjp-62725	161	12	culture	culture	NOUN
bjp-62725	161	13	is	be	AUX
bjp-62725	161	14	modified	modify	VERB
bjp-62725	161	15	by	by	ADP
bjp-62725	161	16	the	the	DET
bjp-62725	161	17	tubulin	tubulin	NOUN
bjp-62725	161	18	polymerization	polymerization	NOUN
bjp-62725	161	19	status	status	NOUN
bjp-62725	161	20	.	.	PUNCT
bjp-62725	162	1	the	the	DET
bjp-62725	162	2	therapeutic	therapeutic	ADJ
bjp-62725	162	3	ramifications	ramification	NOUN
bjp-62725	162	4	of	of	ADP
bjp-62725	162	5	these	these	DET
bjp-62725	162	6	data	datum	NOUN
bjp-62725	162	7	suggest	suggest	VERB
bjp-62725	162	8	that	that	SCONJ
bjp-62725	162	9	the	the	DET
bjp-62725	162	10	key	key	NOUN
bjp-62725	162	11	to	to	ADP
bjp-62725	162	12	curing	cure	VERB
bjp-62725	162	13	osteoarthritis	osteoarthritis	NOUN
bjp-62725	162	14	lies	lie	VERB
bjp-62725	162	15	in	in	ADP
bjp-62725	162	16	comprehending	comprehend	VERB
bjp-62725	162	17	how	how	SCONJ
bjp-62725	162	18	microtubule	microtubule	NOUN
bjp-62725	162	19	production	production	NOUN
bjp-62725	162	20	alters	alter	VERB
bjp-62725	162	21	the	the	DET
bjp-62725	162	22	chondrocytes	chondrocyte	NOUN
bjp-62725	162	23	'	'	PART
bjp-62725	162	24	phenotype	phenotype	NOUN
bjp-62725	162	25	.	.	PUNCT
bjp-62725	163	1	to	to	PART
bjp-62725	163	2	validate	validate	VERB
bjp-62725	163	3	this	this	DET
bjp-62725	163	4	innovative	innovative	ADJ
bjp-62725	163	5	idea	idea	NOUN
bjp-62725	163	6	,	,	PUNCT
bjp-62725	163	7	additional	additional	ADJ
bjp-62725	163	8	research	research	NOUN
bjp-62725	163	9	on	on	ADP
bjp-62725	163	10	colchicine	colchicine	PROPN
bjp-62725	163	11	's	's	PART
bjp-62725	163	12	effects	effect	NOUN
bjp-62725	163	13	on	on	ADP
bjp-62725	163	14	chondrocyte	chondrocyte	NOUN
bjp-62725	163	15	-	-	PUNCT
bjp-62725	163	16	related	relate	VERB
bjp-62725	163	17	cell	cell	NOUN
bjp-62725	163	18	types	type	NOUN
bjp-62725	163	19	and	and	CCONJ
bjp-62725	163	20	animal	animal	NOUN
bjp-62725	163	21	models	model	NOUN
bjp-62725	163	22	is	be	AUX
bjp-62725	163	23	required	require	VERB
bjp-62725	163	24	.	.	PUNCT
bjp-62725	164	1	conclusion	conclusion	NOUN
bjp-62725	164	2	the	the	DET
bjp-62725	164	3	regulating	regulating	NOUN
bjp-62725	164	4	of	of	ADP
bjp-62725	164	5	the	the	DET
bjp-62725	164	6	wnt	wnt	PROPN
bjp-62725	164	7	/	/	SYM
bjp-62725	164	8	β	β	NOUN
bjp-62725	164	9	-	-	ADJ
bjp-62725	164	10	catenin	catenin	ADJ
bjp-62725	164	11	pathway	pathway	NOUN
bjp-62725	164	12	is	be	AUX
bjp-62725	164	13	significant	significant	ADJ
bjp-62725	164	14	in	in	ADP
bjp-62725	164	15	the	the	DET
bjp-62725	164	16	modulation	modulation	NOUN
bjp-62725	164	17	of	of	ADP
bjp-62725	164	18	colchicine	colchicine	NOUN
bjp-62725	164	19	-	-	PUNCT
bjp-62725	164	20	reduced	reduce	VERB
bjp-62725	164	21	microtubule	microtubule	NOUN
bjp-62725	164	22	synthesis	synthesis	NOUN
bjp-62725	164	23	caused	cause	VERB
bjp-62725	164	24	chondrocyte	chondrocyte	NOUN
bjp-62725	164	25	dedifferentiation	dedifferentiation	NOUN
bjp-62725	164	26	.	.	PUNCT
bjp-62725	165	1	financial	financial	ADJ
bjp-62725	165	2	support	support	NOUN
bjp-62725	165	3	this	this	DET
bjp-62725	165	4	work	work	NOUN
bjp-62725	165	5	was	be	AUX
bjp-62725	165	6	supported	support	VERB
bjp-62725	165	7	by	by	ADP
bjp-62725	165	8	the	the	DET
bjp-62725	165	9	national	national	PROPN
bjp-62725	165	10	research	research	PROPN
bjp-62725	165	11	foundation	foundation	PROPN
bjp-62725	165	12	of	of	ADP
bjp-62725	165	13	korea	korea	PROPN
bjp-62725	165	14	(	(	PUNCT
bjp-62725	165	15	nrf	nrf	NOUN
bjp-62725	165	16	)	)	PUNCT
bjp-62725	165	17	funded	fund	VERB
bjp-62725	165	18	by	by	ADP
bjp-62725	165	19	the	the	DET
bjp-62725	165	20	korean	korean	ADJ
bjp-62725	165	21	government	government	NOUN
bjp-62725	165	22	(	(	PUNCT
bjp-62725	165	23	mest	mest	NOUN
bjp-62725	165	24	)	)	PUNCT
bjp-62725	165	25	(	(	PUNCT
bjp-62725	165	26	2020r1a6a3a01100240	2020r1a6a3a01100240	NUM
bjp-62725	165	27	,	,	PUNCT
bjp-62725	165	28	2020r1i1a306969913	2020r1i1a306969913	NUM
bjp-62725	165	29	)	)	PUNCT
bjp-62725	165	30	.	.	PUNCT
bjp-62725	166	1	ethical	ethical	ADJ
bjp-62725	166	2	issue	issue	NOUN
bjp-62725	166	3	the	the	DET
bjp-62725	166	4	ethical	ethical	ADJ
bjp-62725	166	5	committee	committee	NOUN
bjp-62725	166	6	of	of	ADP
bjp-62725	166	7	kongju	kongju	PROPN
bjp-62725	166	8	national	national	PROPN
bjp-62725	166	9	university	university	PROPN
bjp-62725	166	10	approved	approve	VERB
bjp-62725	166	11	this	this	DET
bjp-62725	166	12	animal	animal	NOUN
bjp-62725	166	13	-	-	PUNCT
bjp-62725	166	14	based	base	VERB
bjp-62725	166	15	study	study	NOUN
bjp-62725	166	16	(	(	PUNCT
bjp-62725	166	17	knu_2022	knu_2022	NOUN
bjp-62725	166	18	-	-	PUNCT
bjp-62725	166	19	04	04	NUM
bjp-62725	166	20	)	)	PUNCT
bjp-62725	166	21	.	.	PUNCT
bjp-62725	167	1	conflict	conflict	NOUN
bjp-62725	167	2	of	of	ADP
bjp-62725	167	3	interest	interest	NOUN
bjp-62725	167	4	authors	author	NOUN
bjp-62725	167	5	declare	declare	VERB
bjp-62725	167	6	no	no	DET
bjp-62725	167	7	conflict	conflict	NOUN
bjp-62725	167	8	of	of	ADP
bjp-62725	167	9	interest	interest	NOUN
bjp-62725	167	10	references	reference	NOUN
bjp-62725	167	11	beier	beier	VERB
bjp-62725	167	12	f.	f.	PROPN
bjp-62725	167	13	cartilage	cartilage	NOUN
bjp-62725	167	14	differentiation	differentiation	NOUN
bjp-62725	167	15	and	and	CCONJ
bjp-62725	167	16	the	the	DET
bjp-62725	167	17	actin	actin	NOUN
bjp-62725	167	18	cytoskeleton	cytoskeleton	PROPN
bjp-62725	167	19	:	:	PUNCT
bjp-62725	167	20	cartilage	cartilage	NOUN
bjp-62725	167	21	.	.	PUNCT
bjp-62725	168	1	springer	springer	NOUN
bjp-62725	168	2	,	,	PUNCT
bjp-62725	168	3	2016	2016	NUM
bjp-62725	168	4	,	,	PUNCT
bjp-62725	168	5	pp	pp	ADP
bjp-62725	168	6	253	253	NUM
bjp-62725	168	7	-	-	SYM
bjp-62725	168	8	67	67	NUM
bjp-62725	168	9	.	.	PUNCT
bjp-62725	169	1	chang	chang	PROPN
bjp-62725	169	2	sf	sf	PROPN
bjp-62725	169	3	,	,	PUNCT
bjp-62725	169	4	huang	huang	PROPN
bjp-62725	169	5	kc	kc	PROPN
bjp-62725	169	6	,	,	PUNCT
bjp-62725	169	7	lee	lee	PROPN
bjp-62725	169	8	kh	kh	PROPN
bjp-62725	169	9	,	,	PUNCT
bjp-62725	169	10	chiang	chiang	PROPN
bjp-62725	169	11	yc	yc	PROPN
bjp-62725	169	12	,	,	PUNCT
bjp-62725	169	13	lee	lee	PROPN
bjp-62725	169	14	wr	wr	PROPN
bjp-62725	169	15	,	,	PUNCT
bjp-62725	169	16	hsieh	hsieh	PROPN
bjp-62725	169	17	rz	rz	PROPN
bjp-62725	169	18	,	,	PUNCT
bjp-62725	169	19	su	su	PROPN
bjp-62725	169	20	yp	yp	PROPN
bjp-62725	169	21	,	,	PUNCT
bjp-62725	169	22	wu	wu	PROPN
bjp-62725	169	23	sc	sc	PROPN
bjp-62725	169	24	.	.	PUNCT
bjp-62725	169	25	effects	effect	NOUN
bjp-62725	169	26	of	of	ADP
bjp-62725	169	27	visfatin	visfatin	NOUN
bjp-62725	169	28	on	on	ADP
bjp-62725	169	29	intracellular	intracellular	ADJ
bjp-62725	169	30	mechanics	mechanic	NOUN
bjp-62725	169	31	and	and	CCONJ
bjp-62725	169	32	catabolism	catabolism	NOUN
bjp-62725	169	33	in	in	ADP
bjp-62725	169	34	human	human	ADJ
bjp-62725	169	35	primary	primary	ADJ
bjp-62725	169	36	chondrocytes	chondrocyte	NOUN
bjp-62725	169	37	through	through	ADP
bjp-62725	169	38	glycogen	glycogen	NOUN
bjp-62725	169	39	synthase	synthase	NOUN
bjp-62725	169	40	kinase	kinase	PROPN
bjp-62725	169	41	3β	3β	NUM
bjp-62725	169	42	inactivation	inactivation	NOUN
bjp-62725	169	43	.	.	PUNCT
bjp-62725	170	1	int	int	PROPN
bjp-62725	170	2	j	j	PROPN
bjp-62725	170	3	mol	mol	ADP
bjp-62725	170	4	sci	sci	PROPN
bjp-62725	170	5	.	.	PROPN
bjp-62725	170	6	2021	2021	NUM
bjp-62725	170	7	;	;	PUNCT
bjp-62725	170	8	22	22	NUM
bjp-62725	170	9	:	:	SYM
bjp-62725	170	10	8107	8107	NUM
bjp-62725	170	11	.	.	PUNCT
bjp-62725	171	1	charlier	charlier	PROPN
bjp-62725	171	2	e	e	NOUN
bjp-62725	171	3	,	,	PUNCT
bjp-62725	171	4	deroyer	deroyer	PROPN
bjp-62725	171	5	c	c	NOUN
bjp-62725	171	6	,	,	PUNCT
bjp-62725	171	7	ciregia	ciregia	PROPN
bjp-62725	171	8	f	f	PROPN
bjp-62725	171	9	,	,	PUNCT
bjp-62725	171	10	malaise	malaise	PROPN
bjp-62725	171	11	o	o	NOUN
bjp-62725	171	12	,	,	PUNCT
bjp-62725	171	13	neuville	neuville	PROPN
bjp-62725	171	14	s	s	PROPN
bjp-62725	171	15	,	,	PUNCT
bjp-62725	171	16	plener	plener	NOUN
bjp-62725	171	17	z	z	PROPN
bjp-62725	171	18	,	,	PUNCT
bjp-62725	171	19	malaise	malaise	PROPN
bjp-62725	171	20	m	m	PRON
bjp-62725	171	21	,	,	PUNCT
bjp-62725	171	22	de	de	X
bjp-62725	171	23	seny	seny	PROPN
bjp-62725	171	24	d.	d.	PROPN
bjp-62725	171	25	chondrocyte	chondrocyte	PROPN
bjp-62725	171	26	dedifferentiation	dedifferentiation	NOUN
bjp-62725	171	27	and	and	CCONJ
bjp-62725	171	28	osteoarthritis	osteoarthritis	NOUN
bjp-62725	171	29	(	(	PUNCT
bjp-62725	171	30	oa	oa	PROPN
bjp-62725	171	31	)	)	PUNCT
bjp-62725	171	32	.	.	PUNCT
bjp-62725	172	1	biochem	biochem	PROPN
bjp-62725	172	2	pharmacol	pharmacol	PROPN
bjp-62725	172	3	.	.	PROPN
bjp-62725	173	1	2019	2019	NUM
bjp-62725	173	2	;	;	PUNCT
bjp-62725	173	3	165	165	NUM
bjp-62725	173	4	:	:	SYM
bjp-62725	173	5	49	49	NUM
bjp-62725	173	6	-	-	SYM
bjp-62725	173	7	65	65	NUM
bjp-62725	173	8	.	.	PUNCT
bjp-62725	174	1	fernández	fernández	PROPN
bjp-62725	174	2	-	-	PUNCT
bjp-62725	174	3	torres	torres	PROPN
bjp-62725	174	4	j	j	PROPN
bjp-62725	174	5	,	,	PUNCT
bjp-62725	174	6	zamudio	zamudio	NOUN
bjp-62725	174	7	-	-	PUNCT
bjp-62725	174	8	cuevas	cuevas	PROPN
bjp-62725	174	9	y	y	PROPN
bjp-62725	174	10	,	,	PUNCT
bjp-62725	174	11	lópez	lópez	NOUN
bjp-62725	174	12	-	-	PUNCT
bjp-62725	174	13	reyes	reyes	PROPN
bjp-62725	174	14	a	a	PRON
bjp-62725	174	15	,	,	PUNCT
bjp-62725	174	16	garrido	garrido	ADJ
bjp-62725	174	17	-	-	PUNCT
bjp-62725	174	18	rodríguez	rodríguez	NOUN
bjp-62725	174	19	d	d	NOUN
bjp-62725	174	20	,	,	PUNCT
bjp-62725	174	21	martínez	martínez	PROPN
bjp-62725	174	22	-	-	PUNCT
bjp-62725	174	23	flores	flores	PROPN
bjp-62725	174	24	k	k	PROPN
bjp-62725	174	25	,	,	PUNCT
bjp-62725	174	26	lozada	lozada	PROPN
bjp-62725	174	27	ca	ca	PROPN
bjp-62725	174	28	,	,	PUNCT
bjp-62725	174	29	muñóz	muñóz	PROPN
bjp-62725	174	30	-	-	PUNCT
bjp-62725	174	31	valle	valle	PROPN
bjp-62725	174	32	jf	jf	PROPN
bjp-62725	174	33	,	,	PUNCT
bjp-62725	174	34	oregon	oregon	PROPN
bjp-62725	174	35	-	-	PUNCT
bjp-62725	174	36	romero	romero	PROPN
bjp-62725	174	37	e	e	PROPN
bjp-62725	174	38	,	,	PUNCT
bjp-62725	174	39	martínez	martínez	PROPN
bjp-62725	174	40	-	-	PUNCT
bjp-62725	174	41	nava	nava	PROPN
bjp-62725	174	42	ga	ga	PROPN
bjp-62725	174	43	.	.	PROPN
bjp-62725	174	44	gene	gene	NOUN
bjp-62725	174	45	-	-	PUNCT
bjp-62725	174	46	gene	gene	NOUN
bjp-62725	174	47	interactions	interaction	NOUN
bjp-62725	174	48	of	of	ADP
bjp-62725	174	49	the	the	DET
bjp-62725	174	50	wnt	wnt	NOUN
bjp-62725	174	51	/	/	SYM
bjp-62725	174	52	β	β	NOUN
bjp-62725	174	53	-	-	ADJ
bjp-62725	174	54	catenin	catenin	ADJ
bjp-62725	174	55	signaling	signal	VERB
bjp-62725	174	56	pathway	pathway	NOUN
bjp-62725	174	57	in	in	ADP
bjp-62725	174	58	knee	knee	NOUN
bjp-62725	174	59	osteoarthritis	osteoarthritis	NOUN
bjp-62725	174	60	.	.	PUNCT
bjp-62725	175	1	mol	mol	ADP
bjp-62725	175	2	biol	biol	PROPN
bjp-62725	175	3	rep	rep	PROPN
bjp-62725	175	4	.	.	PROPN
bjp-62725	175	5	2018	2018	NUM
bjp-62725	175	6	:	:	PUNCT
bjp-62725	176	1	45	45	NUM
bjp-62725	176	2	:	:	SYM
bjp-62725	176	3	1089	1089	NUM
bjp-62725	176	4	-	-	SYM
bjp-62725	176	5	98	98	NUM
bjp-62725	176	6	.	.	PUNCT
bjp-62725	177	1	ferrer	ferrer	PROPN
bjp-62725	177	2	md	md	PROPN
bjp-62725	177	3	,	,	PUNCT
bjp-62725	177	4	busquets	busquets	PROPN
bjp-62725	177	5	-	-	PUNCT
bjp-62725	177	6	cortés	cortés	NOUN
bjp-62725	177	7	c	c	NOUN
bjp-62725	177	8	,	,	PUNCT
bjp-62725	177	9	capo	capo	PROPN
bjp-62725	177	10	x	x	PROPN
bjp-62725	177	11	,	,	PUNCT
bjp-62725	177	12	tejada	tejada	PROPN
bjp-62725	177	13	s	s	PROPN
bjp-62725	177	14	,	,	PUNCT
bjp-62725	177	15	tur	tur	PROPN
bjp-62725	177	16	ja	ja	PROPN
bjp-62725	177	17	,	,	PUNCT
bjp-62725	177	18	pons	pons	PROPN
bjp-62725	177	19	a	a	X
bjp-62725	177	20	,	,	PUNCT
bjp-62725	177	21	sureda	sureda	ADJ
bjp-62725	177	22	a.	a.	NOUN
bjp-62725	177	23	cyclooxygenase-2	cyclooxygenase-2	NUM
bjp-62725	177	24	inhibitors	inhibitor	NOUN
bjp-62725	177	25	as	as	ADP
bjp-62725	177	26	a	a	DET
bjp-62725	177	27	therapeutic	therapeutic	ADJ
bjp-62725	177	28	target	target	NOUN
bjp-62725	177	29	in	in	ADP
bjp-62725	177	30	inflammatory	inflammatory	ADJ
bjp-62725	177	31	diseases	disease	NOUN
bjp-62725	177	32	.	.	PUNCT
bjp-62725	178	1	curr	curr	PROPN
bjp-62725	178	2	med	med	PROPN
bjp-62725	178	3	chem	chem	NOUN
bjp-62725	178	4	.	.	PUNCT
bjp-62725	179	1	2019	2019	NUM
bjp-62725	179	2	;	;	PUNCT
bjp-62725	179	3	26	26	NUM
bjp-62725	179	4	:	:	SYM
bjp-62725	179	5	3225	3225	NUM
bjp-62725	179	6	-	-	SYM
bjp-62725	179	7	41	41	NUM
bjp-62725	179	8	.	.	PUNCT
bjp-62725	180	1	ghosh	ghosh	PROPN
bjp-62725	180	2	s	s	PROPN
bjp-62725	180	3	,	,	PUNCT
bjp-62725	180	4	scott	scott	PROPN
bjp-62725	180	5	ak	ak	PROPN
bjp-62725	180	6	,	,	PUNCT
bjp-62725	180	7	seelbinder	seelbinder	PROPN
bjp-62725	180	8	b	b	NOUN
bjp-62725	180	9	,	,	PUNCT
bjp-62725	180	10	barthold	barthold	PROPN
bjp-62725	180	11	je	je	PROPN
bjp-62725	180	12	,	,	PUNCT
bjp-62725	180	13	martin	martin	PROPN
bjp-62725	180	14	bms	bms	PROPN
bjp-62725	180	15	,	,	PUNCT
bjp-62725	180	16	kaonis	kaonis	PROPN
bjp-62725	180	17	s	s	PROPN
bjp-62725	180	18	,	,	PUNCT
bjp-62725	180	19	schneider	schneider	PROPN
bjp-62725	180	20	se	se	PROPN
bjp-62725	180	21	,	,	PUNCT
bjp-62725	180	22	henderson	henderson	PROPN
bjp-62725	180	23	jt	jt	PROPN
bjp-62725	180	24	,	,	PUNCT
bjp-62725	180	25	neu	neu	PROPN
bjp-62725	180	26	cp	cp	PROPN
bjp-62725	180	27	.	.	PUNCT
bjp-62725	180	28	dedifferentiation	dedifferentiation	PROPN
bjp-62725	180	29	alters	alter	VERB
bjp-62725	180	30	chondrocyte	chondrocyte	NOUN
bjp-62725	180	31	nuclear	nuclear	ADJ
bjp-62725	180	32	mechanics	mechanic	NOUN
bjp-62725	180	33	during	during	ADP
bjp-62725	180	34	in	in	ADP
bjp-62725	180	35	vitro	vitro	X
bjp-62725	180	36	culture	culture	NOUN
bjp-62725	180	37	and	and	CCONJ
bjp-62725	180	38	expansion	expansion	NOUN
bjp-62725	180	39	.	.	PUNCT
bjp-62725	181	1	biophys	biophys	PROPN
bjp-62725	181	2	j.	j.	PROPN
bjp-62725	181	3	2022	2022	NUM
bjp-62725	181	4	;	;	PUNCT
bjp-62725	181	5	121	121	NUM
bjp-62725	181	6	:	:	SYM
bjp-62725	181	7	131	131	NUM
bjp-62725	181	8	-	-	SYM
bjp-62725	181	9	41	41	NUM
bjp-62725	181	10	.	.	PUNCT
bjp-62725	182	1	goodson	goodson	PROPN
bjp-62725	182	2	hv	hv	PROPN
bjp-62725	182	3	,	,	PUNCT
bjp-62725	182	4	jonasson	jonasson	VERB
bjp-62725	182	5	em	em	PRON
bjp-62725	182	6	.	.	PUNCT
bjp-62725	183	1	microtubules	microtubule	NOUN
bjp-62725	183	2	and	and	CCONJ
bjp-62725	183	3	microtubuleassociated	microtubuleassociate	VERB
bjp-62725	183	4	proteins	protein	NOUN
bjp-62725	183	5	.	.	PUNCT
bjp-62725	184	1	cold	cold	ADJ
bjp-62725	184	2	spring	spring	NOUN
bjp-62725	184	3	harb	harb	PROPN
bjp-62725	184	4	perspect	perspect	VERB
bjp-62725	184	5	biol	biol	PROPN
bjp-62725	184	6	.	.	PUNCT
bjp-62725	185	1	2018	2018	NUM
bjp-62725	185	2	;	;	PUNCT
bjp-62725	185	3	10	10	NUM
bjp-62725	185	4	:	:	PUNCT
bjp-62725	185	5	a022608	a022608	NOUN
bjp-62725	185	6	.	.	PUNCT
bjp-62725	186	1	guo	guo	PROPN
bjp-62725	186	2	q	q	PROPN
bjp-62725	186	3	,	,	PUNCT
bjp-62725	186	4	chen	chen	PROPN
bjp-62725	186	5	x	x	PROPN
bjp-62725	186	6	,	,	PUNCT
bjp-62725	186	7	chen	chen	PROPN
bjp-62725	186	8	j	j	PROPN
bjp-62725	186	9	,	,	PUNCT
bjp-62725	186	10	zheng	zheng	PROPN
bjp-62725	186	11	g	g	PROPN
bjp-62725	186	12	,	,	PUNCT
bjp-62725	186	13	xie	xie	PROPN
bjp-62725	186	14	c	c	PROPN
bjp-62725	186	15	,	,	PUNCT
bjp-62725	186	16	wu	wu	PROPN
bjp-62725	186	17	h	h	PROPN
bjp-62725	186	18	,	,	PUNCT
bjp-62725	186	19	miao	miao	PROPN
bjp-62725	186	20	z	z	PROPN
bjp-62725	186	21	,	,	PUNCT
bjp-62725	186	22	lin	lin	PROPN
bjp-62725	186	23	y	y	PROPN
bjp-62725	186	24	,	,	PUNCT
bjp-62725	186	25	wang	wang	PROPN
bjp-62725	186	26	x	x	PROPN
bjp-62725	186	27	,	,	PUNCT
bjp-62725	186	28	gao	gao	PROPN
bjp-62725	186	29	w.	w.	PROPN
bjp-62725	186	30	sting	sting	PROPN
bjp-62725	186	31	promotes	promote	VERB
bjp-62725	186	32	senescence	senescence	NOUN
bjp-62725	186	33	,	,	PUNCT
bjp-62725	186	34	apoptosis	apoptosis	NOUN
bjp-62725	186	35	,	,	PUNCT
bjp-62725	186	36	and	and	CCONJ
bjp-62725	186	37	extracellular	extracellular	ADJ
bjp-62725	186	38	matrix	matrix	NOUN
bjp-62725	186	39	degradation	degradation	NOUN
bjp-62725	186	40	in	in	ADP
bjp-62725	186	41	osteoarthritis	osteoarthritis	NOUN
bjp-62725	186	42	via	via	ADP
bjp-62725	186	43	the	the	DET
bjp-62725	186	44	nf	nf	ADJ
bjp-62725	186	45	-	-	PUNCT
bjp-62725	186	46	κb	κb	NOUN
bjp-62725	186	47	signaling	signal	VERB
bjp-62725	186	48	pathway	pathway	NOUN
bjp-62725	186	49	.	.	PUNCT
bjp-62725	187	1	cell	cell	NOUN
bjp-62725	187	2	death	death	NOUN
bjp-62725	187	3	dis	dis	PROPN
bjp-62725	187	4	.	.	PUNCT
bjp-62725	187	5	2021	2021	NUM
bjp-62725	187	6	;	;	PUNCT
bjp-62725	187	7	12	12	NUM
bjp-62725	187	8	:	:	SYM
bjp-62725	187	9	1	1	NUM
bjp-62725	187	10	-	-	SYM
bjp-62725	187	11	14	14	NUM
bjp-62725	187	12	.	.	PUNCT
bjp-62725	188	1	han	han	PROPN
bjp-62725	188	2	y	y	PROPN
bjp-62725	188	3	,	,	PUNCT
bjp-62725	188	4	kim	kim	PROPN
bjp-62725	188	5	sj	sj	PROPN
bjp-62725	188	6	.	.	PUNCT
bjp-62725	188	7	simvastatin	simvastatin	PROPN
bjp-62725	188	8	-	-	PUNCT
bjp-62725	188	9	dependent	dependent	ADJ
bjp-62725	188	10	actin	actin	NOUN
bjp-62725	188	11	cytoskeleton	cytoskeleton	PROPN
bjp-62725	188	12	rearrangement	rearrangement	NOUN
bjp-62725	188	13	regulates	regulate	VERB
bjp-62725	188	14	differentiation	differentiation	NOUN
bjp-62725	188	15	via	via	ADP
bjp-62725	188	16	the	the	DET
bjp-62725	188	17	extracellular	extracellular	ADJ
bjp-62725	188	18	signal	signal	NOUN
bjp-62725	188	19	-	-	PUNCT
bjp-62725	188	20	regulated	regulate	VERB
bjp-62725	188	21	kinase-1/2	kinase-1/2	NOUN
bjp-62725	188	22	and	and	CCONJ
bjp-62725	188	23	p38	p38	PROPN
bjp-62725	188	24	kinase	kinase	NOUN
bjp-62725	188	25	pathways	pathway	NOUN
bjp-62725	188	26	in	in	ADP
bjp-62725	188	27	rabbit	rabbit	NOUN
bjp-62725	188	28	articular	articular	ADJ
bjp-62725	188	29	chondrocytes	chondrocyte	NOUN
bjp-62725	188	30	.	.	PUNCT
bjp-62725	189	1	eur	eur	PROPN
bjp-62725	189	2	j	j	PROPN
bjp-62725	189	3	pharmacol	pharmacol	PROPN
bjp-62725	189	4	.	.	PROPN
bjp-62725	189	5	2018	2018	NUM
bjp-62725	189	6	;	;	PUNCT
bjp-62725	189	7	834	834	NUM
bjp-62725	189	8	:	:	PUNCT
bjp-62725	189	9	197	197	NUM
bjp-62725	189	10	-	-	SYM
bjp-62725	189	11	205	205	NUM
bjp-62725	189	12	.	.	PUNCT
bjp-62725	190	1	han	han	PROPN
bjp-62725	190	2	y	y	PROPN
bjp-62725	190	3	,	,	PUNCT
bjp-62725	190	4	yu	yu	PROPN
bjp-62725	190	5	sm	sm	PROPN
bjp-62725	190	6	,	,	PUNCT
bjp-62725	190	7	shah	shah	PROPN
bjp-62725	190	8	fh	fh	PROPN
bjp-62725	190	9	,	,	PUNCT
bjp-62725	190	10	kim	kim	PROPN
bjp-62725	190	11	sj	sj	PROPN
bjp-62725	190	12	.	.	PROPN
bjp-62725	190	13	subversive	subversive	ADJ
bjp-62725	190	14	molecular	molecular	ADJ
bjp-62725	190	15	role	role	NOUN
bjp-62725	190	16	of	of	ADP
bjp-62725	190	17	krüppel	krüppel	NOUN
bjp-62725	190	18	-	-	PUNCT
bjp-62725	190	19	like	like	ADJ
bjp-62725	190	20	factor	factor	NOUN
bjp-62725	190	21	5	5	NUM
bjp-62725	190	22	in	in	ADP
bjp-62725	190	23	extracellular	extracellular	ADJ
bjp-62725	190	24	matrix	matrix	NOUN
bjp-62725	190	25	degradation	degradation	NOUN
bjp-62725	190	26	and	and	CCONJ
bjp-62725	190	27	chondrocyte	chondrocyte	NOUN
bjp-62725	190	28	dedifferentiation	dedifferentiation	NOUN
bjp-62725	190	29	.	.	PUNCT
bjp-62725	191	1	funct	funct	PROPN
bjp-62725	191	2	integr	integr	PROPN
bjp-62725	191	3	genomics	genomics	PROPN
bjp-62725	191	4	.	.	PUNCT
bjp-62725	192	1	2022	2022	NUM
bjp-62725	192	2	;	;	PUNCT
bjp-62725	192	3	1	1	NUM
bjp-62725	192	4	-	-	SYM
bjp-62725	192	5	7	7	NUM
bjp-62725	192	6	.	.	PUNCT
bjp-62725	193	1	hodgkinson	hodgkinson	PROPN
bjp-62725	193	2	t	t	PROPN
bjp-62725	193	3	,	,	PUNCT
bjp-62725	193	4	kelly	kelly	PROPN
bjp-62725	193	5	dc	dc	PROPN
bjp-62725	193	6	,	,	PUNCT
bjp-62725	193	7	curtin	curtin	PROPN
bjp-62725	193	8	cm	cm	PROPN
bjp-62725	193	9	,	,	PUNCT
bjp-62725	193	10	o’brien	o’brien	PROPN
bjp-62725	193	11	fj	fj	PROPN
bjp-62725	193	12	.	.	PUNCT
bjp-62725	194	1	mechanosignalling	mechanosignalle	VERB
bjp-62725	194	2	in	in	ADP
bjp-62725	194	3	cartilage	cartilage	NOUN
bjp-62725	194	4	:	:	PUNCT
bjp-62725	194	5	an	an	DET
bjp-62725	194	6	emerging	emerge	VERB
bjp-62725	194	7	target	target	NOUN
bjp-62725	194	8	for	for	ADP
bjp-62725	194	9	the	the	DET
bjp-62725	194	10	treatment	treatment	NOUN
bjp-62725	194	11	of	of	ADP
bjp-62725	194	12	osteoarthritis	osteoarthritis	NOUN
bjp-62725	194	13	.	.	PUNCT
bjp-62725	195	1	nat	nat	PROPN
bjp-62725	195	2	rev	rev	PROPN
bjp-62725	195	3	rheumatol	rheumatol	NOUN
bjp-62725	195	4	.	.	PUNCT
bjp-62725	196	1	2022	2022	NUM
bjp-62725	196	2	;	;	PUNCT
bjp-62725	196	3	18	18	NUM
bjp-62725	196	4	:	:	SYM
bjp-62725	196	5	67	67	NUM
bjp-62725	196	6	-	-	SYM
bjp-62725	196	7	84	84	NUM
bjp-62725	196	8	.	.	PUNCT
bjp-62725	197	1	huang	huang	PROPN
bjp-62725	197	2	p	p	PROPN
bjp-62725	197	3	,	,	PUNCT
bjp-62725	197	4	yan	yan	PROPN
bjp-62725	197	5	r	r	PROPN
bjp-62725	197	6	,	,	PUNCT
bjp-62725	197	7	zhang	zhang	PROPN
bjp-62725	197	8	x	x	PROPN
bjp-62725	197	9	,	,	PUNCT
bjp-62725	197	10	wang	wang	PROPN
bjp-62725	197	11	l	l	PROPN
bjp-62725	197	12	,	,	PUNCT
bjp-62725	197	13	ke	ke	PROPN
bjp-62725	197	14	x	x	NOUN
bjp-62725	197	15	,	,	PUNCT
bjp-62725	197	16	and	and	CCONJ
bjp-62725	197	17	qu	qu	PROPN
bjp-62725	197	18	y.	y.	PROPN
bjp-62725	197	19	activating	activate	VERB
bjp-62725	197	20	wnt	wnt	PROPN
bjp-62725	197	21	/	/	SYM
bjp-62725	197	22	β	β	NOUN
bjp-62725	197	23	-	-	ADJ
bjp-62725	197	24	catenin	catenin	ADJ
bjp-62725	197	25	signaling	signal	VERB
bjp-62725	197	26	pathway	pathway	NOUN
bjp-62725	197	27	for	for	ADP
bjp-62725	197	28	disease	disease	NOUN
bjp-62725	197	29	therapy	therapy	NOUN
bjp-62725	197	30	:	:	PUNCT
bjp-62725	197	31	challenges	challenge	NOUN
bjp-62725	197	32	and	and	CCONJ
bjp-62725	197	33	opportunities	opportunity	NOUN
bjp-62725	197	34	.	.	PUNCT
bjp-62725	198	1	pharmacol	pharmacol	VERB
bjp-62725	198	2	ther	ther	ADV
bjp-62725	198	3	.	.	PUNCT
bjp-62725	199	1	2019	2019	NUM
bjp-62725	199	2	;	;	PUNCT
bjp-62725	199	3	196	196	NUM
bjp-62725	199	4	:	:	SYM
bjp-62725	199	5	79	79	NUM
bjp-62725	199	6	-	-	SYM
bjp-62725	199	7	90	90	NUM
bjp-62725	199	8	.	.	PUNCT
bjp-62725	200	1	kim	kim	PROPN
bjp-62725	200	2	m	m	PROPN
bjp-62725	200	3	,	,	PUNCT
bjp-62725	200	4	song	song	PROPN
bjp-62725	200	5	k	k	PROPN
bjp-62725	200	6	,	,	PUNCT
bjp-62725	200	7	jin	jin	PROPN
bjp-62725	200	8	ej	ej	PROPN
bjp-62725	200	9	,	,	PUNCT
bjp-62725	200	10	sonn	sonn	PROPN
bjp-62725	200	11	j.	j.	PROPN
bjp-62725	200	12	staurosporine	staurosporine	PROPN
bjp-62725	200	13	and	and	CCONJ
bjp-62725	200	14	cytochalasin	cytochalasin	PROPN
bjp-62725	200	15	d	d	AUX
bjp-62725	200	16	induce	induce	VERB
bjp-62725	200	17	chondrogenesis	chondrogenesis	NOUN
bjp-62725	200	18	by	by	ADP
bjp-62725	200	19	regulation	regulation	NOUN
bjp-62725	200	20	of	of	ADP
bjp-62725	200	21	actin	actin	NOUN
bjp-62725	200	22	dynamics	dynamic	NOUN
bjp-62725	200	23	in	in	ADP
bjp-62725	200	24	different	different	ADJ
bjp-62725	200	25	way	way	NOUN
bjp-62725	200	26	.	.	PUNCT
bjp-62725	201	1	exp	exp	NOUN
bjp-62725	201	2	mol	mol	ADP
bjp-62725	201	3	med	med	PROPN
bjp-62725	201	4	.	.	PUNCT
bjp-62725	201	5	2012	2012	NUM
bjp-62725	201	6	;	;	PUNCT
bjp-62725	201	7	44	44	NUM
bjp-62725	201	8	:	:	SYM
bjp-62725	201	9	521	521	NUM
bjp-62725	201	10	-	-	SYM
bjp-62725	201	11	28	28	NUM
bjp-62725	201	12	.	.	PUNCT
bjp-62725	202	1	li	li	PROPN
bjp-62725	202	2	h	h	PROPN
bjp-62725	202	3	,	,	PUNCT
bjp-62725	202	4	li	li	PROPN
bjp-62725	202	5	l	l	PROPN
bjp-62725	202	6	,	,	PUNCT
bjp-62725	202	7	min	min	PROPN
bjp-62725	202	8	j	j	PROPN
bjp-62725	202	9	,	,	PUNCT
bjp-62725	202	10	yang	yang	PROPN
bjp-62725	202	11	h	h	PROPN
bjp-62725	202	12	,	,	PUNCT
bjp-62725	202	13	xu	xu	PROPN
bjp-62725	202	14	x	x	PROPN
bjp-62725	202	15	,	,	PUNCT
bjp-62725	202	16	yuan	yuan	PROPN
bjp-62725	202	17	y	y	PROPN
bjp-62725	202	18	,	,	PUNCT
bjp-62725	202	19	and	and	CCONJ
bjp-62725	202	20	wang	wang	PROPN
bjp-62725	202	21	d.	d.	PROPN
bjp-62725	202	22	levels	level	NOUN
bjp-62725	202	23	of	of	ADP
bjp-62725	202	24	metalloproteinase	metalloproteinase	NOUN
bjp-62725	202	25	(	(	PUNCT
bjp-62725	202	26	mmp-3	mmp-3	X
bjp-62725	202	27	,	,	PUNCT
bjp-62725	202	28	mmp-9	mmp-9	NUM
bjp-62725	202	29	)	)	PUNCT
bjp-62725	202	30	,	,	PUNCT
bjp-62725	202	31	nf	nf	ADJ
bjp-62725	202	32	-	-	PUNCT
bjp-62725	202	33	kappab	kappab	NOUN
bjp-62725	202	34	ligand	ligand	NOUN
bjp-62725	202	35	(	(	PUNCT
bjp-62725	202	36	rankl	rankl	PROPN
bjp-62725	202	37	)	)	PUNCT
bjp-62725	202	38	,	,	PUNCT
bjp-62725	202	39	and	and	CCONJ
bjp-62725	202	40	nitric	nitric	ADJ
bjp-62725	202	41	oxide	oxide	NOUN
bjp-62725	202	42	(	(	PUNCT
bjp-62725	202	43	no	no	NOUN
bjp-62725	202	44	)	)	PUNCT
bjp-62725	202	45	in	in	ADP
bjp-62725	202	46	peripheral	peripheral	ADJ
bjp-62725	202	47	blood	blood	NOUN
bjp-62725	202	48	of	of	ADP
bjp-62725	202	49	osteoarthritis	osteoarthritis	NOUN
bjp-62725	202	50	(	(	PUNCT
bjp-62725	202	51	oa	oa	NOUN
bjp-62725	202	52	)	)	PUNCT
bjp-62725	202	53	patients	patient	NOUN
bjp-62725	202	54	.	.	PUNCT
bjp-62725	203	1	clin	clin	PROPN
bjp-62725	203	2	lab	lab	PROPN
bjp-62725	203	3	.	.	PUNCT
bjp-62725	203	4	2012	2012	NUM
bjp-62725	203	5	;	;	PUNCT
bjp-62725	203	6	58	58	NUM
bjp-62725	203	7	:	:	PUNCT
bjp-62725	203	8	755	755	NUM
bjp-62725	203	9	-	-	SYM
bjp-62725	203	10	62	62	NUM
bjp-62725	203	11	.	.	PUNCT
bjp-62725	204	1	li	li	PROPN
bjp-62725	204	2	sh	sh	PROPN
bjp-62725	204	3	,	,	PUNCT
bjp-62725	204	4	wu	wu	PROPN
bjp-62725	204	5	qf	qf	PROPN
bjp-62725	204	6	.	.	PROPN
bjp-62725	204	7	2021	2021	NUM
bjp-62725	204	8	.	.	PUNCT
bjp-62725	205	1	micrornas	microrna	NOUN
bjp-62725	205	2	target	target	VERB
bjp-62725	205	3	on	on	ADP
bjp-62725	205	4	cartilage	cartilage	NOUN
bjp-62725	205	5	extracellular	extracellular	ADJ
bjp-62725	205	6	matrix	matrix	NOUN
bjp-62725	205	7	degradation	degradation	NOUN
bjp-62725	205	8	of	of	ADP
bjp-62725	205	9	knee	knee	NOUN
bjp-62725	205	10	osteoarthritis	osteoarthritis	NOUN
bjp-62725	205	11	.	.	PUNCT
bjp-62725	206	1	eur	eur	PROPN
bjp-62725	206	2	rev	rev	PROPN
bjp-62725	206	3	med	med	PROPN
bjp-62725	206	4	pharmacol	pharmacol	PROPN
bjp-62725	206	5	sci	sci	PROPN
bjp-62725	206	6	.	.	PROPN
bjp-62725	207	1	25	25	NUM
bjp-62725	207	2	:	:	PUNCT
bjp-62725	207	3	1185	1185	NUM
bjp-62725	207	4	-	-	SYM
bjp-62725	207	5	97	97	NUM
bjp-62725	207	6	.	.	PUNCT
bjp-62725	208	1	li	li	PROPN
bjp-62725	208	2	w	w	PROPN
bjp-62725	208	3	,	,	PUNCT
bjp-62725	208	4	xiong	xiong	PROPN
bjp-62725	208	5	y	y	PROPN
bjp-62725	208	6	,	,	PUNCT
bjp-62725	208	7	chen	chen	PROPN
bjp-62725	208	8	w	w	PROPN
bjp-62725	208	9	,	,	PUNCT
bjp-62725	208	10	wu	wu	PROPN
bjp-62725	208	11	l.	l.	PROPN
bjp-62725	208	12	wnt	wnt	PROPN
bjp-62725	208	13	/	/	SYM
bjp-62725	208	14	β‑catenin	β‑catenin	PROPN
bjp-62725	208	15	signaling	signal	VERB
bjp-62725	208	16	may	may	AUX
bjp-62725	208	17	induce	induce	VERB
bjp-62725	208	18	senescence	senescence	NOUN
bjp-62725	208	19	of	of	ADP
bjp-62725	208	20	chondrocytes	chondrocyte	NOUN
bjp-62725	208	21	in	in	ADP
bjp-62725	208	22	osteoarthritis	osteoarthritis	NOUN
bjp-62725	208	23	.	.	PUNCT
bjp-62725	209	1	exp	exp	NOUN
bjp-62725	209	2	ther	ther	PROPN
bjp-62725	209	3	med	me	VERB
bjp-62725	209	4	.	.	PUNCT
bjp-62725	209	5	2020	2020	NUM
bjp-62725	209	6	;	;	PUNCT
bjp-62725	209	7	20	20	NUM
bjp-62725	209	8	:	:	SYM
bjp-62725	209	9	2631	2631	NUM
bjp-62725	209	10	-	-	SYM
bjp-62725	209	11	38	38	NUM
bjp-62725	209	12	.	.	PUNCT
bjp-62725	210	1	lim	lim	PROPN
bjp-62725	210	2	hs	hs	PROPN
bjp-62725	210	3	,	,	PUNCT
bjp-62725	210	4	jang	jang	PROPN
bjp-62725	210	5	y	y	PROPN
bjp-62725	210	6	,	,	PUNCT
bjp-62725	210	7	moon	moon	PROPN
bjp-62725	210	8	bc	bc	PROPN
bjp-62725	210	9	,	,	PUNCT
bjp-62725	210	10	park	park	PROPN
bjp-62725	210	11	g.	g.	PROPN
bjp-62725	210	12	nf	nf	PROPN
bjp-62725	210	13	-	-	PUNCT
bjp-62725	210	14	κb	κb	NOUN
bjp-62725	210	15	signaling	signal	VERB
bjp-62725	210	16	contributes	contribute	VERB
bjp-62725	210	17	to	to	ADP
bjp-62725	210	18	the	the	DET
bjp-62725	210	19	inhibitory	inhibitory	ADJ
bjp-62725	210	20	effects	effect	NOUN
bjp-62725	210	21	of	of	ADP
bjp-62725	210	22	bombyx	bombyx	ADJ
bjp-62725	210	23	batryticatus	batryticatus	NOUN
bjp-62725	210	24	on	on	ADP
bjp-62725	210	25	neuroinfla	neuroinfla	NOUN
bjp-62725	210	26	-	-	PUNCT
bjp-62725	210	27	mmation	mmation	NOUN
bjp-62725	210	28	caused	cause	VERB
bjp-62725	210	29	by	by	ADP
bjp-62725	210	30	mptp	mptp	ADJ
bjp-62725	210	31	toxicity	toxicity	NOUN
bjp-62725	210	32	.	.	PUNCT
bjp-62725	211	1	bangladesh	bangladesh	PROPN
bjp-62725	211	2	j	j	PROPN
bjp-62725	211	3	pharmacol	pharmacol	PROPN
bjp-62725	211	4	.	.	PROPN
bjp-62725	211	5	2021	2021	NUM
bjp-62725	211	6	;	;	PUNCT
bjp-62725	211	7	16	16	NUM
bjp-62725	211	8	:	:	SYM
bjp-62725	211	9	96	96	NUM
bjp-62725	211	10	-	-	SYM
bjp-62725	211	11	102	102	NUM
bjp-62725	211	12	.	.	PUNCT
bjp-62725	212	1	bangladesh	bangladesh	PROPN
bjp-62725	212	2	j	j	PROPN
bjp-62725	212	3	pharmacol	pharmacol	PROPN
bjp-62725	212	4	2023	2023	NUM
bjp-62725	212	5	;	;	PUNCT
bjp-62725	212	6	18	18	NUM
bjp-62725	212	7	:	:	SYM
bjp-62725	212	8	8	8	NUM
bjp-62725	212	9	-	-	SYM
bjp-62725	212	10	16	16	NUM
bjp-62725	212	11	15	15	NUM
bjp-62725	212	12	author	author	NOUN
bjp-62725	212	13	info	info	NOUN
bjp-62725	212	14	song	song	NOUN
bjp-62725	212	15	ja	ja	PROPN
bjp-62725	212	16	kim	kim	PROPN
bjp-62725	212	17	(	(	PUNCT
bjp-62725	212	18	principal	principal	ADJ
bjp-62725	212	19	contact	contact	NOUN
bjp-62725	212	20	)	)	PUNCT
bjp-62725	213	1	e	e	NOUN
bjp-62725	213	2	-	-	NOUN
bjp-62725	213	3	mail	mail	NOUN
bjp-62725	213	4	:	:	PUNCT
bjp-62725	213	5	ksj85@kongju.ac.kr	ksj85@kongju.ac.kr	X
bjp-62725	213	6	first	first	ADJ
bjp-62725	213	7	three	three	NUM
bjp-62725	213	8	authors	author	NOUN
bjp-62725	213	9	contributed	contribute	VERB
bjp-62725	213	10	equally	equally	ADV
bjp-62725	213	11	liu	liu	PROPN
bjp-62725	213	12	xx	xx	PROPN
bjp-62725	213	13	,	,	PUNCT
bjp-62725	213	14	zhu	zhu	PROPN
bjp-62725	213	15	xy	xy	PROPN
bjp-62725	213	16	,	,	PUNCT
bjp-62725	213	17	yu	yu	PROPN
bjp-62725	213	18	z.	z.	PROPN
bjp-62725	213	19	mulberrofuran	mulberrofuran	PROPN
bjp-62725	213	20	g	g	PROPN
bjp-62725	213	21	inhibits	inhibit	VERB
bjp-62725	213	22	proliferation	proliferation	NOUN
bjp-62725	213	23	and	and	CCONJ
bjp-62725	213	24	migration	migration	NOUN
bjp-62725	213	25	by	by	ADP
bjp-62725	213	26	inactivating	inactivate	VERB
bjp-62725	213	27	jak2	jak2	PROPN
bjp-62725	213	28	/	/	SYM
bjp-62725	213	29	stat3	stat3	NOUN
bjp-62725	213	30	signaling	signal	VERB
bjp-62725	213	31	in	in	ADP
bjp-62725	213	32	lung	lung	NOUN
bjp-62725	213	33	cancer	cancer	NOUN
bjp-62725	213	34	cells	cell	NOUN
bjp-62725	213	35	.	.	PUNCT
bjp-62725	214	1	bangladesh	bangladesh	PROPN
bjp-62725	214	2	j	j	PROPN
bjp-62725	214	3	pharmacol	pharmacol	PROPN
bjp-62725	214	4	.	.	PROPN
bjp-62725	214	5	2021	2021	NUM
bjp-62725	214	6	;	;	PUNCT
bjp-62725	214	7	16	16	NUM
bjp-62725	214	8	:	:	SYM
bjp-62725	214	9	134	134	NUM
bjp-62725	214	10	-	-	SYM
bjp-62725	214	11	40	40	NUM
bjp-62725	214	12	.	.	PUNCT
bjp-62725	215	1	malkowski	malkowski	PROPN
bjp-62725	215	2	mg	mg	PROPN
bjp-62725	215	3	.	.	PUNCT
bjp-62725	216	1	the	the	DET
bjp-62725	216	2	cyclooxygenases	cyclooxygenase	NOUN
bjp-62725	216	3	.	.	PUNCT
bjp-62725	217	1	encycl	encycl	PROPN
bjp-62725	217	2	inorg	inorg	PROPN
bjp-62725	217	3	bioinorg	bioinorg	PROPN
bjp-62725	217	4	chem	chem	PROPN
bjp-62725	217	5	.	.	PUNCT
bjp-62725	218	1	2011	2011	NUM
bjp-62725	218	2	;	;	PUNCT
bjp-62725	218	3	1	1	NUM
bjp-62725	218	4	-	-	SYM
bjp-62725	218	5	18	18	NUM
bjp-62725	218	6	.	.	PUNCT
bjp-62725	219	1	ostojic	ostojic	PROPN
bjp-62725	219	2	m	m	PROPN
bjp-62725	219	3	,	,	PUNCT
bjp-62725	219	4	zevrnja	zevrnja	PROPN
bjp-62725	219	5	a	a	X
bjp-62725	219	6	,	,	PUNCT
bjp-62725	219	7	vukojevic	vukojevic	ADJ
bjp-62725	219	8	k	k	NOUN
bjp-62725	219	9	,	,	PUNCT
bjp-62725	219	10	and	and	CCONJ
bjp-62725	219	11	soljic	soljic	NOUN
bjp-62725	219	12	v.	v.	ADP
bjp-62725	219	13	immunofluorescence	immunofluorescence	NOUN
bjp-62725	219	14	analysis	analysis	NOUN
bjp-62725	219	15	of	of	ADP
bjp-62725	219	16	nf	nf	NOUN
bjp-62725	219	17	-	-	PUNCT
bjp-62725	219	18	kb	kb	NOUN
bjp-62725	219	19	and	and	CCONJ
bjp-62725	219	20	inos	ino	NOUN
bjp-62725	219	21	expression	expression	NOUN
bjp-62725	219	22	in	in	ADP
bjp-62725	219	23	different	different	ADJ
bjp-62725	219	24	cell	cell	NOUN
bjp-62725	219	25	populations	population	NOUN
bjp-62725	219	26	during	during	ADP
bjp-62725	219	27	early	early	ADJ
bjp-62725	219	28	and	and	CCONJ
bjp-62725	219	29	advanced	advanced	ADJ
bjp-62725	219	30	knee	knee	NOUN
bjp-62725	219	31	osteoarthritis	osteoarthritis	NOUN
bjp-62725	219	32	.	.	PUNCT
bjp-62725	220	1	int	int	PROPN
bjp-62725	220	2	j	j	PROPN
bjp-62725	220	3	mol	mol	ADP
bjp-62725	220	4	sci	sci	PROPN
bjp-62725	220	5	.	.	PROPN
bjp-62725	220	6	2021	2021	NUM
bjp-62725	220	7	;	;	PUNCT
bjp-62725	220	8	22	22	NUM
bjp-62725	220	9	:	:	SYM
bjp-62725	220	10	6461	6461	NUM
bjp-62725	220	11	.	.	PUNCT
bjp-62725	221	1	pannunzio	pannunzio	PROPN
bjp-62725	221	2	a	a	PRON
bjp-62725	221	3	,	,	PUNCT
bjp-62725	221	4	coluccia	coluccia	PROPN
bjp-62725	221	5	m.	m.	NOUN
bjp-62725	221	6	cyclooxygenase-1	cyclooxygenase-1	PROPN
bjp-62725	221	7	(	(	PUNCT
bjp-62725	221	8	cox-1	cox-1	NUM
bjp-62725	221	9	)	)	PUNCT
bjp-62725	221	10	and	and	CCONJ
bjp-62725	221	11	cox-1	cox-1	PUNCT
bjp-62725	221	12	inhibitors	inhibitor	NOUN
bjp-62725	221	13	in	in	ADP
bjp-62725	221	14	cancer	cancer	NOUN
bjp-62725	221	15	:	:	PUNCT
bjp-62725	221	16	a	a	DET
bjp-62725	221	17	review	review	NOUN
bjp-62725	221	18	of	of	ADP
bjp-62725	221	19	oncology	oncology	NOUN
bjp-62725	221	20	and	and	CCONJ
bjp-62725	221	21	medicinal	medicinal	ADJ
bjp-62725	221	22	chemistry	chemistry	NOUN
bjp-62725	221	23	literature	literature	NOUN
bjp-62725	221	24	.	.	PUNCT
bjp-62725	222	1	pharmaceuticals	pharmaceutical	NOUN
bjp-62725	222	2	2018	2018	NUM
bjp-62725	222	3	;	;	PUNCT
bjp-62725	222	4	11	11	NUM
bjp-62725	222	5	:	:	SYM
bjp-62725	222	6	101	101	NUM
bjp-62725	222	7	.	.	PUNCT
bjp-62725	223	1	shah	shah	PROPN
bjp-62725	223	2	fh	fh	PROPN
bjp-62725	223	3	,	,	PUNCT
bjp-62725	223	4	kim	kim	PROPN
bjp-62725	223	5	sj	sj	PROPN
bjp-62725	223	6	.	.	PUNCT
bjp-62725	223	7	therapeutic	therapeutic	ADJ
bjp-62725	223	8	role	role	NOUN
bjp-62725	223	9	of	of	ADP
bjp-62725	223	10	medicinal	medicinal	ADJ
bjp-62725	223	11	plant	plant	NOUN
bjp-62725	223	12	extracts	extract	NOUN
bjp-62725	223	13	and	and	CCONJ
bjp-62725	223	14	bioactive	bioactive	ADJ
bjp-62725	223	15	compounds	compound	NOUN
bjp-62725	223	16	in	in	ADP
bjp-62725	223	17	osteoarthritis	osteoarthritis	NOUN
bjp-62725	223	18	.	.	PUNCT
bjp-62725	224	1	adv	adv	PROPN
bjp-62725	224	2	tradit	tradit	PROPN
bjp-62725	224	3	med	me	VERB
bjp-62725	224	4	.	.	PUNCT
bjp-62725	225	1	2022	2022	NUM
bjp-62725	225	2	,	,	PUNCT
bjp-62725	225	3	1	1	NUM
bjp-62725	225	4	-	-	SYM
bjp-62725	225	5	8	8	NUM
bjp-62725	225	6	.	.	PUNCT
bjp-62725	226	1	shen	shen	PROPN
bjp-62725	226	2	s	s	PROPN
bjp-62725	226	3	,	,	PUNCT
bjp-62725	226	4	hou	hou	PROPN
bjp-62725	226	5	y	y	PROPN
bjp-62725	226	6	,	,	PUNCT
bjp-62725	226	7	wu	wu	PROPN
bjp-62725	226	8	y.	y.	PROPN
bjp-62725	226	9	tongxinluo	tongxinluo	PROPN
bjp-62725	226	10	preserves	preserve	VERB
bjp-62725	226	11	the	the	DET
bjp-62725	226	12	renal	renal	ADJ
bjp-62725	226	13	function	function	NOUN
bjp-62725	226	14	in	in	ADP
bjp-62725	226	15	diabetic	diabetic	ADJ
bjp-62725	226	16	kidney	kidney	NOUN
bjp-62725	226	17	disease	disease	NOUN
bjp-62725	226	18	via	via	ADP
bjp-62725	226	19	protecting	protect	VERB
bjp-62725	226	20	the	the	DET
bjp-62725	226	21	hk-2	hk-2	PROPN
bjp-62725	226	22	cells	cell	NOUN
bjp-62725	226	23	from	from	ADP
bjp-62725	226	24	the	the	DET
bjp-62725	226	25	patterns	pattern	NOUN
bjp-62725	226	26	of	of	ADP
bjp-62725	226	27	programmed	program	VERB
bjp-62725	226	28	cell	cell	NOUN
bjp-62725	226	29	death	death	NOUN
bjp-62725	226	30	.	.	PUNCT
bjp-62725	227	1	bangladesh	bangladesh	PROPN
bjp-62725	227	2	j	j	PROPN
bjp-62725	227	3	pharmacol	pharmacol	PROPN
bjp-62725	227	4	.	.	PROPN
bjp-62725	227	5	2021	2021	NUM
bjp-62725	227	6	;	;	PUNCT
bjp-62725	227	7	16	16	NUM
bjp-62725	227	8	:	:	SYM
bjp-62725	227	9	52	52	NUM
bjp-62725	227	10	-	-	SYM
bjp-62725	227	11	64	64	NUM
bjp-62725	227	12	.	.	PUNCT
bjp-62725	228	1	shi	shi	PROPN
bjp-62725	228	2	y	y	PROPN
bjp-62725	228	3	,	,	PUNCT
bjp-62725	228	4	hu	hu	PROPN
bjp-62725	229	1	x	x	PROPN
bjp-62725	229	2	,	,	PUNCT
bjp-62725	229	3	cheng	cheng	PROPN
bjp-62725	229	4	j	j	PROPN
bjp-62725	229	5	,	,	PUNCT
bjp-62725	229	6	zhang	zhang	PROPN
bjp-62725	229	7	x	x	PROPN
bjp-62725	229	8	,	,	PUNCT
bjp-62725	229	9	zhao	zhao	PROPN
bjp-62725	229	10	f	f	PROPN
bjp-62725	229	11	,	,	PUNCT
bjp-62725	229	12	shi	shi	PROPN
bjp-62725	229	13	w	w	PROPN
bjp-62725	229	14	,	,	PUNCT
bjp-62725	229	15	ren	ren	PROPN
bjp-62725	229	16	b	b	NUM
bjp-62725	229	17	,	,	PUNCT
bjp-62725	229	18	yu	yu	PROPN
bjp-62725	229	19	h	h	PROPN
bjp-62725	229	20	,	,	PUNCT
bjp-62725	229	21	yang	yang	PROPN
bjp-62725	229	22	p	p	PROPN
bjp-62725	229	23	,	,	PUNCT
bjp-62725	229	24	li	li	PROPN
bjp-62725	229	25	z.	z.	PROPN
bjp-62725	229	26	a	a	DET
bjp-62725	229	27	small	small	ADJ
bjp-62725	229	28	molecule	molecule	NOUN
bjp-62725	229	29	promotes	promote	VERB
bjp-62725	229	30	cartilage	cartilage	NOUN
bjp-62725	229	31	extracellular	extracellular	ADJ
bjp-62725	229	32	matrix	matrix	NOUN
bjp-62725	229	33	generation	generation	NOUN
bjp-62725	229	34	and	and	CCONJ
bjp-62725	229	35	inhibits	inhibit	VERB
bjp-62725	229	36	osteoarthritis	osteoarthritis	NOUN
bjp-62725	229	37	development	development	NOUN
bjp-62725	229	38	.	.	PUNCT
bjp-62725	230	1	nat	nat	PROPN
bjp-62725	230	2	commun	commun	PROPN
bjp-62725	230	3	.	.	PROPN
bjp-62725	231	1	2019	2019	NUM
bjp-62725	231	2	;	;	PUNCT
bjp-62725	231	3	10	10	NUM
bjp-62725	231	4	:	:	SYM
bjp-62725	231	5	1	1	NUM
bjp-62725	231	6	-	-	SYM
bjp-62725	231	7	14	14	NUM
bjp-62725	231	8	.	.	PUNCT
bjp-62725	232	1	sun	sun	PROPN
bjp-62725	232	2	y	y	PROPN
bjp-62725	232	3	,	,	PUNCT
bjp-62725	232	4	leng	leng	PROPN
bjp-62725	232	5	p	p	PROPN
bjp-62725	232	6	,	,	PUNCT
bjp-62725	232	7	li	li	PROPN
bjp-62725	232	8	d	d	PROPN
bjp-62725	232	9	,	,	PUNCT
bjp-62725	232	10	gao	gao	PROPN
bjp-62725	232	11	h	h	PROPN
bjp-62725	232	12	,	,	PUNCT
bjp-62725	232	13	li	li	PROPN
bjp-62725	232	14	z	z	PROPN
bjp-62725	232	15	,	,	PUNCT
bjp-62725	232	16	li	li	PROPN
bjp-62725	232	17	c	c	PROPN
bjp-62725	232	18	,	,	PUNCT
bjp-62725	232	19	zhang	zhang	PROPN
bjp-62725	232	20	h.	h.	PROPN
bjp-62725	232	21	mechanism	mechanism	NOUN
bjp-62725	232	22	of	of	ADP
bjp-62725	232	23	abnormal	abnormal	ADJ
bjp-62725	232	24	chondrocyte	chondrocyte	NOUN
bjp-62725	232	25	proliferation	proliferation	NOUN
bjp-62725	232	26	induced	induce	VERB
bjp-62725	232	27	by	by	ADP
bjp-62725	232	28	piezo1sirna	piezo1sirna	NOUN
bjp-62725	232	29	exposed	expose	VERB
bjp-62725	232	30	to	to	ADP
bjp-62725	232	31	mechanical	mechanical	ADJ
bjp-62725	232	32	stretch	stretch	NOUN
bjp-62725	232	33	.	.	PUNCT
bjp-62725	232	34	biomed	biome	VERB
bjp-62725	232	35	res	re	NOUN
bjp-62725	232	36	int	int	NOUN
bjp-62725	232	37	.	.	PUNCT
bjp-62725	233	1	2020	2020	NUM
bjp-62725	233	2	:	:	PUNCT
bjp-62725	234	1	2020	2020	NUM
bjp-62725	234	2	.	.	PUNCT
bjp-62725	235	1	wang	wang	PROPN
bjp-62725	235	2	d	d	PROPN
bjp-62725	235	3	,	,	PUNCT
bjp-62725	235	4	cabalag	cabalag	PROPN
bjp-62725	235	5	cs	cs	PROPN
bjp-62725	235	6	,	,	PUNCT
bjp-62725	235	7	clemons	clemons	PROPN
bjp-62725	235	8	nj	nj	PROPN
bjp-62725	235	9	,	,	PUNCT
bjp-62725	235	10	dubois	dubois	PROPN
bjp-62725	235	11	rn	rn	PROPN
bjp-62725	235	12	.	.	PROPN
bjp-62725	235	13	cyclooxygenases	cyclooxygenase	NOUN
bjp-62725	235	14	and	and	CCONJ
bjp-62725	235	15	prostaglandins	prostaglandin	NOUN
bjp-62725	235	16	in	in	ADP
bjp-62725	235	17	tumor	tumor	NOUN
bjp-62725	235	18	immunology	immunology	NOUN
bjp-62725	235	19	and	and	CCONJ
bjp-62725	235	20	microenvironment	microenvironment	NOUN
bjp-62725	235	21	of	of	ADP
bjp-62725	235	22	gastrointestinal	gastrointestinal	ADJ
bjp-62725	235	23	cancer	cancer	NOUN
bjp-62725	235	24	.	.	PUNCT
bjp-62725	236	1	gastroenterology	gastroenterology	NOUN
bjp-62725	236	2	.	.	PUNCT
bjp-62725	237	1	2021	2021	NUM
bjp-62725	237	2	;	;	PUNCT
bjp-62725	237	3	161	161	NUM
bjp-62725	237	4	:	:	SYM
bjp-62725	237	5	1813	1813	NUM
bjp-62725	237	6	-	-	SYM
bjp-62725	237	7	29	29	NUM
bjp-62725	237	8	.	.	PUNCT
bjp-62725	238	1	whittaker	whittaker	PROPN
bjp-62725	238	2	jl	jl	PROPN
bjp-62725	238	3	,	,	PUNCT
bjp-62725	238	4	runhaar	runhaar	PROPN
bjp-62725	238	5	j	j	PROPN
bjp-62725	238	6	,	,	PUNCT
bjp-62725	238	7	bierma	bierma	NOUN
bjp-62725	238	8	-	-	PUNCT
bjp-62725	238	9	zeinstra	zeinstra	PROPN
bjp-62725	238	10	s	s	PROPN
bjp-62725	238	11	,	,	PUNCT
bjp-62725	238	12	roos	roo	VERB
bjp-62725	238	13	em	em	PRON
bjp-62725	238	14	.	.	PUNCT
bjp-62725	239	1	a	a	DET
bjp-62725	239	2	lifespan	lifespan	ADJ
bjp-62725	239	3	approach	approach	NOUN
bjp-62725	239	4	to	to	ADP
bjp-62725	239	5	osteoarthritis	osteoarthritis	NOUN
bjp-62725	239	6	prevention	prevention	NOUN
bjp-62725	239	7	.	.	PUNCT
bjp-62725	240	1	osteoarthr	osteoarthr	PROPN
bjp-62725	240	2	cartil	cartil	PROPN
bjp-62725	240	3	.	.	PUNCT
bjp-62725	240	4	2021	2021	NUM
bjp-62725	240	5	;	;	PUNCT
bjp-62725	240	6	29	29	NUM
bjp-62725	240	7	:	:	SYM
bjp-62725	240	8	1638–1653	1638–1653	NUM
bjp-62725	240	9	.	.	PUNCT
bjp-62725	240	10	xiao	xiao	PROPN
bjp-62725	240	11	y	y	PROPN
bjp-62725	240	12	,	,	PUNCT
bjp-62725	240	13	liu	liu	PROPN
bjp-62725	240	14	l	l	PROPN
bjp-62725	240	15	,	,	PUNCT
bjp-62725	240	16	zheng	zheng	PROPN
bjp-62725	240	17	y	y	PROPN
bjp-62725	240	18	,	,	PUNCT
bjp-62725	240	19	liu	liu	PROPN
bjp-62725	240	20	w	w	PROPN
bjp-62725	240	21	,	,	PUNCT
bjp-62725	240	22	xu	xu	PROPN
bjp-62725	240	23	y.	y.	PROPN
bjp-62725	240	24	kaempferol	kaempferol	PROPN
bjp-62725	240	25	attenuates	attenuate	VERB
bjp-62725	240	26	the	the	DET
bjp-62725	240	27	effects	effect	NOUN
bjp-62725	240	28	of	of	ADP
bjp-62725	240	29	xist	xist	PROPN
bjp-62725	240	30	/	/	SYM
bjp-62725	240	31	mir-130a	mir-130a	PROPN
bjp-62725	240	32	/	/	SYM
bjp-62725	240	33	stat3	stat3	NOUN
bjp-62725	240	34	on	on	ADP
bjp-62725	240	35	inflammation	inflammation	NOUN
bjp-62725	240	36	and	and	CCONJ
bjp-62725	240	37	extracellular	extracellular	ADJ
bjp-62725	240	38	matrix	matrix	NOUN
bjp-62725	240	39	degradation	degradation	NOUN
bjp-62725	240	40	in	in	ADP
bjp-62725	240	41	osteoarthritis	osteoarthritis	NOUN
bjp-62725	240	42	.	.	PUNCT
bjp-62725	241	1	future	future	ADJ
bjp-62725	241	2	med	med	ADJ
bjp-62725	241	3	chem	chem	NOUN
bjp-62725	241	4	.	.	PUNCT
bjp-62725	242	1	2021	2021	NUM
bjp-62725	242	2	;	;	PUNCT
bjp-62725	242	3	13	13	NUM
bjp-62725	242	4	:	:	SYM
bjp-62725	242	5	1451	1451	NUM
bjp-62725	242	6	-	-	SYM
bjp-62725	242	7	64	64	NUM
bjp-62725	242	8	.	.	PUNCT
bjp-62725	243	1	yu	yu	PROPN
bjp-62725	243	2	sm	sm	PROPN
bjp-62725	243	3	,	,	PUNCT
bjp-62725	243	4	han	han	PROPN
bjp-62725	243	5	y	y	PROPN
bjp-62725	243	6	,	,	PUNCT
bjp-62725	243	7	kim	kim	PROPN
bjp-62725	243	8	sj	sj	PROPN
bjp-62725	243	9	.	.	PUNCT
bjp-62725	244	1	simvastatin	simvastatin	PROPN
bjp-62725	244	2	induces	induce	VERB
bjp-62725	244	3	differentiation	differentiation	NOUN
bjp-62725	244	4	in	in	ADP
bjp-62725	244	5	rabbit	rabbit	NOUN
bjp-62725	244	6	articular	articular	ADJ
bjp-62725	244	7	chondrocytes	chondrocyte	NOUN
bjp-62725	244	8	via	via	ADP
bjp-62725	244	9	wnt	wnt	PROPN
bjp-62725	244	10	/	/	SYM
bjp-62725	244	11	β	β	NOUN
bjp-62725	244	12	-	-	ADJ
bjp-62725	244	13	catenin	catenin	ADJ
bjp-62725	244	14	pathway	pathway	NOUN
bjp-62725	244	15	.	.	PUNCT
bjp-62725	245	1	eur	eur	PROPN
bjp-62725	245	2	j	j	PROPN
bjp-62725	245	3	pharmacol	pharmacol	PROPN
bjp-62725	245	4	.	.	PROPN
bjp-62725	245	5	2019	2019	NUM
bjp-62725	245	6	;	;	PUNCT
bjp-62725	245	7	863	863	NUM
bjp-62725	245	8	:	:	PUNCT
bjp-62725	245	9	172672	172672	NUM
bjp-62725	245	10	.	.	PUNCT
bjp-62725	246	1	yu	yu	PROPN
bjp-62725	246	2	sm	sm	PROPN
bjp-62725	246	3	,	,	PUNCT
bjp-62725	246	4	kim	kim	PROPN
bjp-62725	246	5	s.	s.	PROPN
bjp-62725	246	6	retinoic	retinoic	PROPN
bjp-62725	246	7	acid	acid	PROPN
bjp-62725	246	8	potentiates	potentiate	VERB
bjp-62725	246	9	nitric	nitric	ADJ
bjp-62725	246	10	oxide	oxide	NOUN
bjp-62725	246	11	-	-	PUNCT
bjp-62725	246	12	induced	induce	VERB
bjp-62725	246	13	dedifferentiation	dedifferentiation	NOUN
bjp-62725	246	14	through	through	ADP
bjp-62725	246	15	the	the	DET
bjp-62725	246	16	erk	erk	PROPN
bjp-62725	246	17	pathway	pathway	NOUN
bjp-62725	246	18	in	in	ADP
bjp-62725	246	19	rabbit	rabbit	NOUN
bjp-62725	246	20	articular	articular	ADJ
bjp-62725	246	21	chondrocytes	chondrocyte	NOUN
bjp-62725	246	22	.	.	PUNCT
bjp-62725	247	1	j	j	PROPN
bjp-62725	247	2	life	life	PROPN
bjp-62725	247	3	sci	sci	PROPN
bjp-62725	247	4	.	.	PROPN
bjp-62725	247	5	2011	2011	NUM
bjp-62725	247	6	;	;	PUNCT
bjp-62725	247	7	21	21	NUM
bjp-62725	247	8	:	:	PUNCT
bjp-62725	247	9	534	534	NUM
bjp-62725	247	10	-	-	SYM
bjp-62725	247	11	41	41	NUM
bjp-62725	247	12	.	.	PUNCT
bjp-62725	248	1	zhang	zhang	PROPN
bjp-62725	248	2	t	t	PROPN
bjp-62725	248	3	,	,	PUNCT
bjp-62725	248	4	ma	ma	PROPN
bjp-62725	248	5	c	c	PROPN
bjp-62725	248	6	,	,	PUNCT
bjp-62725	248	7	zhang	zhang	PROPN
bjp-62725	248	8	z	z	PROPN
bjp-62725	248	9	,	,	PUNCT
bjp-62725	248	10	zhang	zhang	PROPN
bjp-62725	248	11	h	h	PROPN
bjp-62725	248	12	,	,	PUNCT
bjp-62725	248	13	hu	hu	PROPN
bjp-62725	248	14	h.	h.	PROPN
bjp-62725	248	15	nf‐κb	nf‐κb	PRON
bjp-62725	248	16	signaling	signal	VERB
bjp-62725	248	17	in	in	ADP
bjp-62725	248	18	inflammation	inflammation	NOUN
bjp-62725	248	19	and	and	CCONJ
bjp-62725	248	20	cancer	cancer	NOUN
bjp-62725	248	21	.	.	PUNCT
bjp-62725	249	1	med	med	ADJ
bjp-62725	249	2	comm	comm	NOUN
bjp-62725	249	3	.	.	PUNCT
bjp-62725	249	4	2021	2021	NUM
bjp-62725	249	5	;	;	PUNCT
bjp-62725	249	6	2	2	NUM
bjp-62725	249	7	:	:	SYM
bjp-62725	249	8	618	618	NUM
bjp-62725	249	9	-	-	SYM
bjp-62725	249	10	53	53	NUM
bjp-62725	249	11	.	.	PUNCT
bjp-62725	250	1	zheng	zheng	PROPN
bjp-62725	250	2	l	l	PROPN
bjp-62725	250	3	,	,	PUNCT
bjp-62725	250	4	zhang	zhang	PROPN
bjp-62725	250	5	z	z	PROPN
bjp-62725	250	6	,	,	PUNCT
bjp-62725	250	7	sheng	sheng	PROPN
bjp-62725	250	8	p	p	NOUN
bjp-62725	250	9	,	,	PUNCT
bjp-62725	250	10	mobasheri	mobasheri	PROPN
bjp-62725	250	11	a.	a.	NOUN
bjp-62725	250	12	the	the	DET
bjp-62725	250	13	role	role	NOUN
bjp-62725	250	14	of	of	ADP
bjp-62725	250	15	metabolism	metabolism	NOUN
bjp-62725	250	16	in	in	ADP
bjp-62725	250	17	chondrocyte	chondrocyte	PROPN
bjp-62725	250	18	dysfunction	dysfunction	NOUN
bjp-62725	250	19	and	and	CCONJ
bjp-62725	250	20	the	the	DET
bjp-62725	250	21	progression	progression	NOUN
bjp-62725	250	22	of	of	ADP
bjp-62725	250	23	osteoarthritis	osteoarthritis	NOUN
bjp-62725	250	24	.	.	PUNCT
bjp-62725	251	1	ageing	age	VERB
bjp-62725	251	2	res	re	NOUN
bjp-62725	251	3	rev	rev	PROPN
bjp-62725	251	4	.	.	PROPN
bjp-62725	251	5	2021	2021	NUM
bjp-62725	251	6	;	;	PUNCT
bjp-62725	251	7	66	66	NUM
bjp-62725	251	8	:	:	SYM
bjp-62725	251	9	101249	101249	NUM
bjp-62725	251	10	.	.	PUNCT
bjp-62725	252	1	16	16	NUM
bjp-62725	252	2	bangladesh	bangladesh	PROPN
bjp-62725	252	3	j	j	PROPN
bjp-62725	252	4	pharmacol	pharmacol	PROPN
bjp-62725	252	5	2023	2023	NUM
bjp-62725	252	6	;	;	PUNCT
bjp-62725	252	7	18	18	NUM
bjp-62725	252	8	:	:	SYM
bjp-62725	252	9	8	8	NUM
bjp-62725	252	10	-	-	SYM
bjp-62725	252	11	16	16	NUM
bjp-62725	252	12	mailto:ksj85@kongju.ac.kr	mailto:ksj85@kongju.ac.kr	PROPN