id	sid	tid	token	lemma	pos
bjp-70889	1	1	bangladesh	bangladesh	PROPN
bjp-70889	1	2	journal	journal	PROPN
bjp-70889	1	3	of	of	ADP
bjp-70889	1	4	pharmacology	pharmacology	NOUN
bjp-70889	1	5	research	research	NOUN
bjp-70889	1	6	article	article	NOUN
bjp-70889	1	7	bjp	bjp	NOUN
bjp-70889	1	8	introduction	introduction	NOUN
bjp-70889	1	9	cervical	cervical	ADJ
bjp-70889	1	10	intraepithelial	intraepithelial	ADJ
bjp-70889	1	11	neoplasia	neoplasia	NOUN
bjp-70889	1	12	serves	serve	VERB
bjp-70889	1	13	a	a	DET
bjp-70889	1	14	precursor	precursor	NOUN
bjp-70889	1	15	lesion	lesion	NOUN
bjp-70889	1	16	to	to	ADP
bjp-70889	1	17	cervical	cervical	ADJ
bjp-70889	1	18	cancer	cancer	NOUN
bjp-70889	1	19	,	,	PUNCT
bjp-70889	1	20	primarily	primarily	ADV
bjp-70889	1	21	arising	arise	VERB
bjp-70889	1	22	from	from	ADP
bjp-70889	1	23	persistent	persistent	ADJ
bjp-70889	1	24	infection	infection	NOUN
bjp-70889	1	25	with	with	ADP
bjp-70889	1	26	high	high	ADJ
bjp-70889	1	27	-	-	PUNCT
bjp-70889	1	28	risk	risk	NOUN
bjp-70889	1	29	human	human	ADJ
bjp-70889	1	30	papillomavirus	papillomavirus	NOUN
bjp-70889	1	31	strains	strain	VERB
bjp-70889	1	32	.	.	PUNCT
bjp-70889	2	1	during	during	ADP
bjp-70889	2	2	the	the	DET
bjp-70889	2	3	lesion	lesion	NOUN
bjp-70889	2	4	,	,	PUNCT
bjp-70889	2	5	the	the	DET
bjp-70889	2	6	human	human	ADJ
bjp-70889	2	7	papillomavirus	papillomavirus	NOUN
bjp-70889	2	8	genome	genome	NOUN
bjp-70889	2	9	can	can	AUX
bjp-70889	2	10	integrate	integrate	VERB
bjp-70889	2	11	into	into	ADP
bjp-70889	2	12	that	that	PRON
bjp-70889	2	13	of	of	ADP
bjp-70889	2	14	the	the	DET
bjp-70889	2	15	host	host	NOUN
bjp-70889	2	16	,	,	PUNCT
bjp-70889	2	17	leading	lead	VERB
bjp-70889	2	18	to	to	ADP
bjp-70889	2	19	an	an	DET
bjp-70889	2	20	overexpression	overexpression	NOUN
bjp-70889	2	21	of	of	ADP
bjp-70889	2	22	the	the	DET
bjp-70889	2	23	e6	e6	PROPN
bjp-70889	2	24	and	and	CCONJ
bjp-70889	2	25	e7	e7	PROPN
bjp-70889	2	26	oncoproteins	oncoprotein	NOUN
bjp-70889	2	27	which	which	PRON
bjp-70889	2	28	can	can	AUX
bjp-70889	2	29	disrupt	disrupt	VERB
bjp-70889	2	30	the	the	DET
bjp-70889	2	31	normal	normal	ADJ
bjp-70889	2	32	cell	cell	NOUN
bjp-70889	2	33	cycle	cycle	NOUN
bjp-70889	2	34	and	and	CCONJ
bjp-70889	2	35	causing	cause	VERB
bjp-70889	2	36	immortalization	immortalization	NOUN
bjp-70889	2	37	(	(	PUNCT
bjp-70889	2	38	trope	trope	NOUN
bjp-70889	2	39	et	et	PROPN
bjp-70889	2	40	al	al	PROPN
bjp-70889	2	41	.	.	PROPN
bjp-70889	2	42	,	,	PUNCT
bjp-70889	2	43	2009	2009	NUM
bjp-70889	2	44	)	)	PUNCT
bjp-70889	2	45	.	.	PUNCT
bjp-70889	3	1	if	if	SCONJ
bjp-70889	3	2	human	human	ADJ
bjp-70889	3	3	papillomavirus	papillomavirus	NOUN
bjp-70889	3	4	infection	infection	NOUN
bjp-70889	3	5	continues	continue	VERB
bjp-70889	3	6	during	during	ADP
bjp-70889	3	7	squamous	squamous	ADJ
bjp-70889	3	8	metaplasia	metaplasia	NOUN
bjp-70889	3	9	,	,	PUNCT
bjp-70889	3	10	it	it	PRON
bjp-70889	3	11	can	can	AUX
bjp-70889	3	12	lead	lead	VERB
bjp-70889	3	13	to	to	ADP
bjp-70889	3	14	cervical	cervical	ADJ
bjp-70889	3	15	intraepithelial	intraepithelial	ADJ
bjp-70889	3	16	neoplasia	neoplasia	NOUN
bjp-70889	3	17	aggravation	aggravation	NOUN
bjp-70889	3	18	,	,	PUNCT
bjp-70889	3	19	which	which	PRON
bjp-70889	3	20	may	may	AUX
bjp-70889	3	21	ultimately	ultimately	ADV
bjp-70889	3	22	cause	cause	VERB
bjp-70889	3	23	invasive	invasive	ADJ
bjp-70889	3	24	cervical	cervical	ADJ
bjp-70889	3	25	cancer	cancer	NOUN
bjp-70889	3	26	and	and	CCONJ
bjp-70889	3	27	threaten	threaten	VERB
bjp-70889	3	28	the	the	DET
bjp-70889	3	29	patient	patient	NOUN
bjp-70889	3	30	's	's	PART
bjp-70889	3	31	life	life	NOUN
bjp-70889	3	32	(	(	PUNCT
bjp-70889	3	33	doorbar	doorbar	NOUN
bjp-70889	3	34	et	et	PROPN
bjp-70889	3	35	al	al	PROPN
bjp-70889	3	36	.	.	PROPN
bjp-70889	3	37	,	,	PUNCT
bjp-70889	3	38	2015	2015	NUM
bjp-70889	3	39	)	)	PUNCT
bjp-70889	3	40	.	.	PUNCT
bjp-70889	4	1	currently	currently	ADV
bjp-70889	4	2	,	,	PUNCT
bjp-70889	4	3	the	the	DET
bjp-70889	4	4	treatment	treatment	NOUN
bjp-70889	4	5	of	of	ADP
bjp-70889	4	6	cervical	cervical	ADJ
bjp-70889	4	7	intraepithelial	intraepithelial	ADJ
bjp-70889	4	8	neoplasia	neoplasia	NOUN
bjp-70889	4	9	encompasses	encompass	VERB
bjp-70889	4	10	various	various	ADJ
bjp-70889	4	11	modalities	modality	NOUN
bjp-70889	4	12	such	such	ADJ
bjp-70889	4	13	as	as	ADP
bjp-70889	4	14	excision	excision	NOUN
bjp-70889	4	15	therapy	therapy	NOUN
bjp-70889	4	16	,	,	PUNCT
bjp-70889	4	17	ablation	ablation	NOUN
bjp-70889	4	18	therapy	therapy	NOUN
bjp-70889	4	19	,	,	PUNCT
bjp-70889	4	20	inter	inter	PROPN
bjp-70889	4	21	feron	feron	PROPN
bjp-70889	4	22	,	,	PUNCT
bjp-70889	4	23	and	and	CCONJ
bjp-70889	4	24	traditional	traditional	ADJ
bjp-70889	4	25	chinese	chinese	ADJ
bjp-70889	4	26	medicine	medicine	NOUN
bjp-70889	4	27	preparations	preparation	NOUN
bjp-70889	4	28	(	(	PUNCT
bjp-70889	4	29	hoffman	hoffman	NOUN
bjp-70889	4	30	et	et	PROPN
bjp-70889	4	31	al	al	PROPN
bjp-70889	4	32	.	.	PROPN
bjp-70889	4	33	,	,	PUNCT
bjp-70889	4	34	2017	2017	NUM
bjp-70889	4	35	;	;	PUNCT
bjp-70889	4	36	liontos	liontos	PROPN
bjp-70889	4	37	et	et	PROPN
bjp-70889	4	38	al	al	PROPN
bjp-70889	4	39	.	.	PROPN
bjp-70889	4	40	,	,	PUNCT
bjp-70889	4	41	2019	2019	NUM
bjp-70889	4	42	)	)	PUNCT
bjp-70889	4	43	.	.	PUNCT
bjp-70889	5	1	numerous	numerous	ADJ
bjp-70889	5	2	retrospective	retrospective	ADJ
bjp-70889	5	3	studies	study	NOUN
bjp-70889	5	4	have	have	AUX
bjp-70889	5	5	shown	show	VERB
bjp-70889	5	6	the	the	DET
bjp-70889	5	7	limitations	limitation	NOUN
bjp-70889	5	8	of	of	ADP
bjp-70889	5	9	surgery	surgery	NOUN
bjp-70889	5	10	such	such	ADJ
bjp-70889	5	11	as	as	ADP
bjp-70889	5	12	postoperative	postoperative	ADJ
bjp-70889	5	13	resi	resi	NOUN
bjp-70889	5	14	dual	dual	ADJ
bjp-70889	5	15	,	,	PUNCT
bjp-70889	5	16	recurrence	recurrence	NOUN
bjp-70889	5	17	,	,	PUNCT
bjp-70889	5	18	low	low	ADJ
bjp-70889	5	19	virus	virus	NOUN
bjp-70889	5	20	clearance	clearance	NOUN
bjp-70889	5	21	rate	rate	NOUN
bjp-70889	5	22	,	,	PUNCT
bjp-70889	5	23	and	and	CCONJ
bjp-70889	5	24	low	low	ADJ
bjp-70889	5	25	cervical	cervical	ADJ
bjp-70889	5	26	function	function	NOUN
bjp-70889	5	27	and	and	CCONJ
bjp-70889	5	28	fertility	fertility	NOUN
bjp-70889	5	29	(	(	PUNCT
bjp-70889	5	30	ghaemmaghami	ghaemmaghami	VERB
bjp-70889	5	31	et	et	PROPN
bjp-70889	5	32	al	al	PROPN
bjp-70889	5	33	.	.	PROPN
bjp-70889	5	34	,	,	PUNCT
bjp-70889	5	35	2007	2007	NUM
bjp-70889	5	36	;	;	PUNCT
bjp-70889	5	37	zhu	zhu	PROPN
bjp-70889	5	38	et	et	PROPN
bjp-70889	5	39	al	al	PROPN
bjp-70889	5	40	.	.	PROPN
bjp-70889	5	41	,	,	PUNCT
bjp-70889	5	42	2015	2015	NUM
bjp-70889	5	43	;	;	PUNCT
bjp-70889	5	44	athanasiou	athanasiou	NOUN
bjp-70889	5	45	et	et	PROPN
bjp-70889	5	46	al	al	PROPN
bjp-70889	5	47	.	.	PROPN
bjp-70889	5	48	,	,	PUNCT
bjp-70889	5	49	2022	2022	NUM
bjp-70889	5	50	)	)	PUNCT
bjp-70889	5	51	.	.	PUNCT
bjp-70889	6	1	furthermore	furthermore	ADV
bjp-70889	6	2	,	,	PUNCT
bjp-70889	6	3	interferon	interferon	ADJ
bjp-70889	6	4	preparations	preparation	NOUN
bjp-70889	6	5	,	,	PUNCT
bjp-70889	6	6	are	be	AUX
bjp-70889	6	7	costly	costly	ADJ
bjp-70889	6	8	with	with	ADP
bjp-70889	6	9	a	a	DET
bjp-70889	6	10	prolonged	prolonged	ADJ
bjp-70889	6	11	application	application	NOUN
bjp-70889	6	12	cycle	cycle	NOUN
bjp-70889	6	13	,	,	PUNCT
bjp-70889	6	14	posing	pose	VERB
bjp-70889	6	15	challenges	challenge	NOUN
bjp-70889	6	16	for	for	ADP
bjp-70889	6	17	patient	patient	ADJ
bjp-70889	6	18	acceptance	acceptance	NOUN
bjp-70889	6	19	.	.	PUNCT
bjp-70889	7	1	in	in	ADP
bjp-70889	7	2	recent	recent	ADJ
bjp-70889	7	3	years	year	NOUN
bjp-70889	7	4	,	,	PUNCT
bjp-70889	7	5	there	there	PRON
bjp-70889	7	6	has	have	AUX
bjp-70889	7	7	been	be	AUX
bjp-70889	7	8	a	a	DET
bjp-70889	7	9	growing	grow	VERB
bjp-70889	7	10	interest	interest	NOUN
bjp-70889	7	11	in	in	ADP
bjp-70889	7	12	exploring	explore	VERB
bjp-70889	7	13	natural	natural	ADJ
bjp-70889	7	14	compounds	compound	NOUN
bjp-70889	7	15	as	as	ADP
bjp-70889	7	16	alternative	alternative	ADJ
bjp-70889	7	17	treatments	treatment	NOUN
bjp-70889	7	18	for	for	ADP
bjp-70889	7	19	cervical	cervical	ADJ
bjp-70889	7	20	intraepithelial	intraepithelial	ADJ
bjp-70889	7	21	neoplasia	neoplasia	NOUN
bjp-70889	7	22	.	.	PUNCT
bjp-70889	8	1	one	one	NUM
bjp-70889	8	2	such	such	ADJ
bjp-70889	8	3	promising	promising	ADJ
bjp-70889	8	4	compound	compound	NOUN
bjp-70889	8	5	is	be	AUX
bjp-70889	8	6	berberine	berberine	NOUN
bjp-70889	8	7	,	,	PUNCT
bjp-70889	8	8	a	a	DET
bjp-70889	8	9	plant	plant	NOUN
bjp-70889	8	10	-	-	PUNCT
bjp-70889	8	11	derived	derive	VERB
bjp-70889	8	12	alkaloid	alkaloid	NOUN
bjp-70889	8	13	known	know	VERB
bjp-70889	8	14	for	for	ADP
bjp-70889	8	15	its	its	PRON
bjp-70889	8	16	reported	report	VERB
bjp-70889	8	17	antiproliferative	antiproliferative	NOUN
bjp-70889	8	18	and	and	CCONJ
bjp-70889	8	19	proapoptotic	proapoptotic	ADJ
bjp-70889	8	20	effects	effect	NOUN
bjp-70889	8	21	in	in	ADP
bjp-70889	8	22	various	various	ADJ
bjp-70889	8	23	cancer	cancer	NOUN
bjp-70889	8	24	cell	cell	NOUN
bjp-70889	8	25	lines	line	NOUN
bjp-70889	8	26	(	(	PUNCT
bjp-70889	8	27	liu	liu	PROPN
bjp-70889	8	28	et	et	PROPN
bjp-70889	8	29	al	al	PROPN
bjp-70889	8	30	.	.	PROPN
bjp-70889	8	31	,	,	PUNCT
bjp-70889	8	32	2019	2019	NUM
bjp-70889	8	33	;	;	PUNCT
bjp-70889	8	34	rui	rui	PROPN
bjp-70889	8	35	et	et	PROPN
bjp-70889	8	36	al	al	PROPN
bjp-70889	8	37	.	.	PROPN
bjp-70889	8	38	,	,	PUNCT
bjp-70889	8	39	abstract	abstract	ADJ
bjp-70889	8	40	this	this	DET
bjp-70889	8	41	study	study	NOUN
bjp-70889	8	42	aims	aim	VERB
bjp-70889	8	43	to	to	PART
bjp-70889	8	44	investigate	investigate	VERB
bjp-70889	8	45	the	the	DET
bjp-70889	8	46	effect	effect	NOUN
bjp-70889	8	47	of	of	ADP
bjp-70889	8	48	berberine	berberine	NOUN
bjp-70889	8	49	on	on	ADP
bjp-70889	8	50	necroptosis	necroptosis	NOUN
bjp-70889	8	51	in	in	ADP
bjp-70889	8	52	cervical	cervical	ADJ
bjp-70889	8	53	h8	h8	PROPN
bjp-70889	8	54	cells	cell	NOUN
bjp-70889	8	55	.	.	PUNCT
bjp-70889	9	1	cck-8	cck-8	VERB
bjp-70889	10	1	assay	assay	PROPN
bjp-70889	10	2	was	be	AUX
bjp-70889	10	3	used	use	VERB
bjp-70889	10	4	to	to	PART
bjp-70889	10	5	assess	assess	VERB
bjp-70889	10	6	cell	cell	NOUN
bjp-70889	10	7	proliferation	proliferation	NOUN
bjp-70889	10	8	activity	activity	NOUN
bjp-70889	10	9	.	.	PUNCT
bjp-70889	11	1	the	the	DET
bjp-70889	11	2	expression	expression	NOUN
bjp-70889	11	3	levels	level	NOUN
bjp-70889	11	4	of	of	ADP
bjp-70889	11	5	necroptosis	necroptosis	NOUN
bjp-70889	11	6	key	key	ADJ
bjp-70889	11	7	markers	marker	NOUN
bjp-70889	11	8	receptorinteracting	receptorinteracte	VERB
bjp-70889	11	9	protein	protein	NOUN
bjp-70889	11	10	kinase	kinase	NOUN
bjp-70889	11	11	1	1	NUM
bjp-70889	11	12	(	(	PUNCT
bjp-70889	11	13	ripk1	ripk1	PROPN
bjp-70889	11	14	)	)	PUNCT
bjp-70889	11	15	,	,	PUNCT
bjp-70889	11	16	mlkl	mlkl	X
bjp-70889	11	17	,	,	PUNCT
bjp-70889	11	18	p	p	NOUN
bjp-70889	11	19	-	-	PUNCT
bjp-70889	11	20	mlkl	mlkl	NOUN
bjp-70889	11	21	,	,	PUNCT
bjp-70889	11	22	and	and	CCONJ
bjp-70889	11	23	apoptosisrelated	apoptosisrelate	VERB
bjp-70889	11	24	caspase-8	caspase-8	PROPN
bjp-70889	11	25	,	,	PUNCT
bjp-70889	11	26	caspase-3	caspase-3	NUM
bjp-70889	11	27	were	be	AUX
bjp-70889	11	28	analyzed	analyze	VERB
bjp-70889	11	29	through	through	ADP
bjp-70889	11	30	qrt	qrt	NOUN
bjp-70889	11	31	-	-	PUNCT
bjp-70889	11	32	pcr	pcr	ADJ
bjp-70889	11	33	,	,	PUNCT
bjp-70889	11	34	western	western	ADJ
bjp-70889	11	35	blot	blot	NOUN
bjp-70889	11	36	,	,	PUNCT
bjp-70889	11	37	and	and	CCONJ
bjp-70889	11	38	immunofluorescence	immunofluorescence	NOUN
bjp-70889	11	39	.	.	PUNCT
bjp-70889	12	1	mechanistic	mechanistic	ADJ
bjp-70889	12	2	studies	study	NOUN
bjp-70889	12	3	were	be	AUX
bjp-70889	12	4	con	con	NOUN
bjp-70889	12	5	ducted	ducte	VERB
bjp-70889	12	6	using	use	VERB
bjp-70889	12	7	the	the	DET
bjp-70889	12	8	ripk1	ripk1	ADJ
bjp-70889	12	9	kinase	kinase	PROPN
bjp-70889	12	10	inhibitor	inhibitor	NOUN
bjp-70889	12	11	necrostatin	necrostatin	NOUN
bjp-70889	12	12	-1	-1	PUNCT
bjp-70889	12	13	(	(	PUNCT
bjp-70889	12	14	nec-1	nec-1	NOUN
bjp-70889	12	15	)	)	PUNCT
bjp-70889	12	16	.	.	PUNCT
bjp-70889	13	1	the	the	DET
bjp-70889	13	2	results	result	NOUN
bjp-70889	13	3	showed	show	VERB
bjp-70889	13	4	that	that	SCONJ
bjp-70889	13	5	berberine	berberine	NOUN
bjp-70889	13	6	could	could	AUX
bjp-70889	13	7	inhibit	inhibit	VERB
bjp-70889	13	8	h8	h8	PROPN
bjp-70889	13	9	cell	cell	NOUN
bjp-70889	13	10	proliferation	proliferation	NOUN
bjp-70889	13	11	in	in	ADP
bjp-70889	13	12	a	a	DET
bjp-70889	13	13	timeand	timeand	NOUN
bjp-70889	13	14	dose	dose	NOUN
bjp-70889	13	15	-	-	PUNCT
bjp-70889	13	16	dependent	dependent	ADJ
bjp-70889	13	17	manner	manner	NOUN
bjp-70889	13	18	(	(	PUNCT
bjp-70889	13	19	p<0.05	p<0.05	NOUN
bjp-70889	13	20	)	)	PUNCT
bjp-70889	13	21	.	.	PUNCT
bjp-70889	14	1	it	it	PRON
bjp-70889	14	2	increased	increase	VERB
bjp-70889	14	3	the	the	DET
bjp-70889	14	4	expression	expression	NOUN
bjp-70889	14	5	of	of	ADP
bjp-70889	14	6	ripk1	ripk1	NOUN
bjp-70889	14	7	and	and	CCONJ
bjp-70889	14	8	mlkl	mlkl	PROPN
bjp-70889	14	9	(	(	PUNCT
bjp-70889	14	10	p<0.05	p<0.05	NOUN
bjp-70889	14	11	)	)	PUNCT
bjp-70889	14	12	,	,	PUNCT
bjp-70889	14	13	while	while	SCONJ
bjp-70889	14	14	inhibiting	inhibit	VERB
bjp-70889	14	15	the	the	DET
bjp-70889	14	16	expression	expression	NOUN
bjp-70889	14	17	of	of	ADP
bjp-70889	14	18	caspase-8	caspase-8	NOUN
bjp-70889	14	19	and	and	CCONJ
bjp-70889	14	20	caspase-3(p<0.05	caspase-3(p<0.05	PROPN
bjp-70889	14	21	)	)	PUNCT
bjp-70889	14	22	.	.	PUNCT
bjp-70889	15	1	nec-1	nec-1	ADP
bjp-70889	15	2	inhibitor	inhibitor	NOUN
bjp-70889	15	3	decreased	decrease	VERB
bjp-70889	15	4	the	the	DET
bjp-70889	15	5	expression	expression	NOUN
bjp-70889	15	6	of	of	ADP
bjp-70889	15	7	ripk1	ripk1	NOUN
bjp-70889	15	8	and	and	CCONJ
bjp-70889	15	9	mlkl	mlkl	PROPN
bjp-70889	15	10	after	after	ADP
bjp-70889	15	11	the	the	DET
bjp-70889	15	12	intervention	intervention	NOUN
bjp-70889	15	13	of	of	ADP
bjp-70889	15	14	berberine	berberine	NOUN
bjp-70889	15	15	(	(	PUNCT
bjp-70889	15	16	p<0.05	p<0.05	PROPN
bjp-70889	15	17	)	)	PUNCT
bjp-70889	15	18	.	.	PUNCT
bjp-70889	16	1	therefore	therefore	ADV
bjp-70889	16	2	,	,	PUNCT
bjp-70889	16	3	berberine	berberine	NOUN
bjp-70889	16	4	induces	induce	VERB
bjp-70889	16	5	cervical	cervical	ADJ
bjp-70889	16	6	h8	h8	PROPN
bjp-70889	16	7	cell	cell	NOUN
bjp-70889	16	8	death	death	NOUN
bjp-70889	16	9	through	through	ADP
bjp-70889	16	10	the	the	DET
bjp-70889	16	11	activation	activation	NOUN
bjp-70889	16	12	of	of	ADP
bjp-70889	16	13	ripk1	ripk1	NOUN
bjp-70889	16	14	-	-	PUNCT
bjp-70889	16	15	mediated	mediate	VERB
bjp-70889	16	16	necroptosis	necroptosis	NOUN
bjp-70889	16	17	.	.	PUNCT
bjp-70889	17	1	article	article	NOUN
bjp-70889	17	2	info	info	NOUN
bjp-70889	17	3	received	receive	VERB
bjp-70889	17	4	:	:	PUNCT
bjp-70889	17	5	10	10	NUM
bjp-70889	17	6	january	january	NOUN
bjp-70889	17	7	2024	2024	NUM
bjp-70889	17	8	accepted	accept	VERB
bjp-70889	17	9	:	:	PUNCT
bjp-70889	17	10	4	4	NUM
bjp-70889	17	11	march	march	NOUN
bjp-70889	17	12	2024	2024	NUM
bjp-70889	17	13	available	available	ADJ
bjp-70889	17	14	online	online	NOUN
bjp-70889	17	15	:	:	PUNCT
bjp-70889	17	16	15	15	NUM
bjp-70889	17	17	march	march	NOUN
bjp-70889	17	18	2024	2024	NUM
bjp-70889	17	19	doi	doi	NOUN
bjp-70889	17	20	:	:	PUNCT
bjp-70889	17	21	10.3329	10.3329	NUM
bjp-70889	17	22	/	/	SYM
bjp-70889	17	23	bjp.v19i1.70889	bjp.v19i1.70889	PROPN
bjp-70889	17	24	cite	cite	VERB
bjp-70889	17	25	this	this	DET
bjp-70889	17	26	article	article	NOUN
bjp-70889	17	27	:	:	PUNCT
bjp-70889	17	28	wang	wang	PROPN
bjp-70889	17	29	m	m	PROPN
bjp-70889	17	30	,	,	PUNCT
bjp-70889	17	31	chen	chen	PROPN
bjp-70889	17	32	h	h	PROPN
bjp-70889	17	33	,	,	PUNCT
bjp-70889	17	34	wu	wu	PROPN
bjp-70889	18	1	q	q	PROPN
bjp-70889	18	2	,	,	PUNCT
bjp-70889	18	3	huang	huang	PROPN
bjp-70889	18	4	y	y	PROPN
bjp-70889	18	5	,	,	PUNCT
bjp-70889	18	6	zhou	zhou	PROPN
bjp-70889	18	7	y.	y.	PROPN
bjp-70889	18	8	berberine	berberine	PROPN
bjp-70889	18	9	triggers	trigger	VERB
bjp-70889	18	10	necroptosis	necroptosis	NOUN
bjp-70889	18	11	of	of	ADP
bjp-70889	18	12	cervical	cervical	ADJ
bjp-70889	18	13	h8	h8	NOUN
bjp-70889	18	14	cells	cell	NOUN
bjp-70889	18	15	by	by	ADP
bjp-70889	18	16	activating	activate	VERB
bjp-70889	18	17	receptor	receptor	NOUN
bjp-70889	18	18	-	-	PUNCT
bjp-70889	18	19	interacting	interact	VERB
bjp-70889	18	20	protein	protein	NOUN
bjp-70889	18	21	kinase	kinase	NOUN
bjp-70889	18	22	1	1	X
bjp-70889	18	23	.	.	PUNCT
bjp-70889	19	1	bangladesh	bangladesh	PROPN
bjp-70889	19	2	j	j	PROPN
bjp-70889	19	3	pharmacol	pharmacol	PROPN
bjp-70889	19	4	.	.	PUNCT
bjp-70889	20	1	2024	2024	NUM
bjp-70889	20	2	;	;	PUNCT
bjp-70889	20	3	19	19	NUM
bjp-70889	20	4	:	:	SYM
bjp-70889	20	5	13	13	NUM
bjp-70889	20	6	-	-	SYM
bjp-70889	20	7	22	22	NUM
bjp-70889	20	8	.	.	PUNCT
bjp-70889	21	1	berberine	berberine	NOUN
bjp-70889	21	2	triggers	trigger	NOUN
bjp-70889	21	3	necroptosis	necroptosis	NOUN
bjp-70889	21	4	of	of	ADP
bjp-70889	21	5	cervical	cervical	ADJ
bjp-70889	21	6	h8	h8	NOUN
bjp-70889	21	7	cells	cell	NOUN
bjp-70889	21	8	by	by	ADP
bjp-70889	21	9	activating	activate	VERB
bjp-70889	21	10	receptor	receptor	NOUN
bjp-70889	21	11	-	-	PUNCT
bjp-70889	21	12	interacting	interact	VERB
bjp-70889	21	13	protein	protein	NOUN
bjp-70889	21	14	kinase	kinase	NOUN
bjp-70889	21	15	1	1	NUM
bjp-70889	21	16	mengting	mengting	NOUN
bjp-70889	21	17	wang1	wang1	NOUN
bjp-70889	21	18	,	,	PUNCT
bjp-70889	21	19	huixian	huixian	ADJ
bjp-70889	21	20	chen1	chen1	PROPN
bjp-70889	21	21	,	,	PUNCT
bjp-70889	21	22	qian	qian	PROPN
bjp-70889	21	23	wu2	wu2	PROPN
bjp-70889	21	24	,	,	PUNCT
bjp-70889	21	25	yan	yan	PROPN
bjp-70889	21	26	huang1	huang1	PROPN
bjp-70889	21	27	and	and	CCONJ
bjp-70889	21	28	yuzhen	yuzhen	PROPN
bjp-70889	21	29	zhou1	zhou1	PROPN
bjp-70889	21	30	1department	1department	NUM
bjp-70889	21	31	of	of	ADP
bjp-70889	21	32	obstetrics	obstetric	NOUN
bjp-70889	21	33	and	and	CCONJ
bjp-70889	21	34	gynecology	gynecology	NOUN
bjp-70889	21	35	,	,	PUNCT
bjp-70889	21	36	2department	2department	NUM
bjp-70889	21	37	of	of	ADP
bjp-70889	21	38	critical	critical	ADJ
bjp-70889	21	39	care	care	NOUN
bjp-70889	21	40	medicine	medicine	NOUN
bjp-70889	21	41	,	,	PUNCT
bjp-70889	21	42	suzhou	suzhou	PROPN
bjp-70889	21	43	hospital	hospital	NOUN
bjp-70889	21	44	of	of	ADP
bjp-70889	21	45	integrated	integrate	VERB
bjp-70889	21	46	traditional	traditional	ADJ
bjp-70889	21	47	chinese	chinese	ADJ
bjp-70889	21	48	and	and	CCONJ
bjp-70889	21	49	western	western	ADJ
bjp-70889	21	50	medicine	medicine	NOUN
bjp-70889	21	51	,	,	PUNCT
bjp-70889	21	52	suzhou	suzhou	PROPN
bjp-70889	21	53	,	,	PUNCT
bjp-70889	21	54	jiangsu	jiangsu	PROPN
bjp-70889	21	55	215101	215101	NUM
bjp-70889	21	56	,	,	PUNCT
bjp-70889	21	57	china	china	PROPN
bjp-70889	21	58	.	.	PUNCT
bjp-70889	22	1	this	this	DET
bjp-70889	22	2	work	work	NOUN
bjp-70889	22	3	is	be	AUX
bjp-70889	22	4	licensed	license	VERB
bjp-70889	22	5	under	under	ADP
bjp-70889	22	6	a	a	DET
bjp-70889	22	7	creative	creative	ADJ
bjp-70889	22	8	commons	common	NOUN
bjp-70889	22	9	attribution	attribution	NOUN
bjp-70889	22	10	4.0	4.0	NUM
bjp-70889	22	11	license	license	NOUN
bjp-70889	22	12	.	.	PUNCT
bjp-70889	23	1	you	you	PRON
bjp-70889	23	2	are	be	AUX
bjp-70889	23	3	free	free	ADJ
bjp-70889	23	4	to	to	PART
bjp-70889	23	5	copy	copy	VERB
bjp-70889	23	6	,	,	PUNCT
bjp-70889	23	7	distribute	distribute	VERB
bjp-70889	23	8	and	and	CCONJ
bjp-70889	23	9	perform	perform	VERB
bjp-70889	23	10	the	the	DET
bjp-70889	23	11	work	work	NOUN
bjp-70889	23	12	.	.	PUNCT
bjp-70889	24	1	you	you	PRON
bjp-70889	24	2	must	must	AUX
bjp-70889	24	3	attribute	attribute	VERB
bjp-70889	24	4	the	the	DET
bjp-70889	24	5	work	work	NOUN
bjp-70889	24	6	in	in	ADP
bjp-70889	24	7	the	the	DET
bjp-70889	24	8	manner	manner	NOUN
bjp-70889	24	9	specified	specify	VERB
bjp-70889	24	10	by	by	ADP
bjp-70889	24	11	the	the	DET
bjp-70889	24	12	author	author	NOUN
bjp-70889	24	13	or	or	CCONJ
bjp-70889	24	14	licensor	licensor	NOUN
bjp-70889	24	15	.	.	PUNCT
bjp-70889	25	1	a	a	DET
bjp-70889	25	2	journal	journal	NOUN
bjp-70889	25	3	of	of	ADP
bjp-70889	25	4	the	the	DET
bjp-70889	25	5	bangladesh	bangladesh	NOUN
bjp-70889	25	6	pharmacological	pharmacological	ADJ
bjp-70889	25	7	society	society	NOUN
bjp-70889	25	8	(	(	PUNCT
bjp-70889	25	9	bdps	bdps	NOUN
bjp-70889	25	10	)	)	PUNCT
bjp-70889	25	11	bangladesh	bangladesh	PROPN
bjp-70889	25	12	j	j	PROPN
bjp-70889	25	13	pharmacol	pharmacol	PROPN
bjp-70889	25	14	2024	2024	NUM
bjp-70889	25	15	;	;	PUNCT
bjp-70889	25	16	19	19	NUM
bjp-70889	25	17	:	:	SYM
bjp-70889	25	18	13	13	NUM
bjp-70889	25	19	-	-	SYM
bjp-70889	25	20	22	22	NUM
bjp-70889	25	21	journal	journal	NOUN
bjp-70889	25	22	homepage	homepage	NOUN
bjp-70889	25	23	:	:	PUNCT
bjp-70889	25	24	www.bdpsjournal.org	www.bdpsjournal.org	NUM
bjp-70889	25	25	;	;	PUNCT
bjp-70889	25	26	www.banglajol.info	www.banglajol.info	PROPN
bjp-70889	25	27	abstracted	abstract	VERB
bjp-70889	25	28	/	/	SYM
bjp-70889	25	29	indexed	index	VERB
bjp-70889	25	30	in	in	ADP
bjp-70889	25	31	academic	academic	ADJ
bjp-70889	25	32	search	search	NOUN
bjp-70889	25	33	complete	complete	ADJ
bjp-70889	25	34	,	,	PUNCT
bjp-70889	25	35	agroforestry	agroforestry	NOUN
bjp-70889	25	36	abstracts	abstract	NOUN
bjp-70889	25	37	,	,	PUNCT
bjp-70889	25	38	asia	asia	PROPN
bjp-70889	25	39	journals	journal	NOUN
bjp-70889	25	40	online	online	ADV
bjp-70889	25	41	,	,	PUNCT
bjp-70889	25	42	bangladesh	bangladesh	NOUN
bjp-70889	25	43	journals	journal	NOUN
bjp-70889	25	44	online	online	ADV
bjp-70889	25	45	,	,	PUNCT
bjp-70889	25	46	biological	biological	ADJ
bjp-70889	25	47	abstracts	abstract	NOUN
bjp-70889	25	48	,	,	PUNCT
bjp-70889	25	49	biosis	biosis	NOUN
bjp-70889	25	50	previews	preview	NOUN
bjp-70889	25	51	,	,	PUNCT
bjp-70889	25	52	cab	cab	NOUN
bjp-70889	25	53	abstracts	abstract	NOUN
bjp-70889	25	54	,	,	PUNCT
bjp-70889	25	55	current	current	ADJ
bjp-70889	25	56	abstracts	abstract	NOUN
bjp-70889	25	57	,	,	PUNCT
bjp-70889	25	58	directory	directory	NOUN
bjp-70889	25	59	of	of	ADP
bjp-70889	25	60	open	open	ADJ
bjp-70889	25	61	access	access	NOUN
bjp-70889	25	62	journals	journal	NOUN
bjp-70889	25	63	,	,	PUNCT
bjp-70889	25	64	embase	embase	NOUN
bjp-70889	25	65	/	/	SYM
bjp-70889	25	66	excerpta	excerpta	NOUN
bjp-70889	25	67	medica	medica	NOUN
bjp-70889	25	68	,	,	PUNCT
bjp-70889	25	69	global	global	ADJ
bjp-70889	25	70	health	health	NOUN
bjp-70889	25	71	,	,	PUNCT
bjp-70889	25	72	google	google	PROPN
bjp-70889	25	73	scholar	scholar	NOUN
bjp-70889	25	74	,	,	PUNCT
bjp-70889	25	75	hinari	hinari	X
bjp-70889	25	76	(	(	PUNCT
bjp-70889	25	77	who	who	PRON
bjp-70889	25	78	)	)	PUNCT
bjp-70889	25	79	,	,	PUNCT
bjp-70889	25	80	international	international	ADJ
bjp-70889	25	81	pharmaceutical	pharmaceutical	ADJ
bjp-70889	25	82	abstracts	abstract	NOUN
bjp-70889	25	83	,	,	PUNCT
bjp-70889	25	84	open	open	ADJ
bjp-70889	25	85	j	j	PROPN
bjp-70889	25	86	-	-	PUNCT
bjp-70889	25	87	gate	gate	NOUN
bjp-70889	25	88	,	,	PUNCT
bjp-70889	25	89	science	science	NOUN
bjp-70889	25	90	citation	citation	NOUN
bjp-70889	25	91	index	index	NOUN
bjp-70889	25	92	expanded	expand	VERB
bjp-70889	25	93	,	,	PUNCT
bjp-70889	25	94	scopus	scopus	NOUN
bjp-70889	25	95	and	and	CCONJ
bjp-70889	25	96	social	social	ADJ
bjp-70889	25	97	sciences	sciences	PROPN
bjp-70889	25	98	citation	citation	NOUN
bjp-70889	25	99	index	index	NOUN
bjp-70889	25	100	issn	issn	PROPN
bjp-70889	25	101	:	:	PUNCT
bjp-70889	25	102	1991	1991	NUM
bjp-70889	25	103	-	-	SYM
bjp-70889	25	104	0088	0088	NUM
bjp-70889	25	105	2020	2020	NUM
bjp-70889	25	106	)	)	PUNCT
bjp-70889	25	107	.	.	PUNCT
bjp-70889	26	1	berberine	berberine	PROPN
bjp-70889	26	2	has	have	AUX
bjp-70889	26	3	demonstrated	demonstrate	VERB
bjp-70889	26	4	the	the	DET
bjp-70889	26	5	ability	ability	NOUN
bjp-70889	26	6	to	to	PART
bjp-70889	26	7	inhibit	inhibit	VERB
bjp-70889	26	8	the	the	DET
bjp-70889	26	9	proliferation	proliferation	NOUN
bjp-70889	26	10	and	and	CCONJ
bjp-70889	26	11	invasion	invasion	NOUN
bjp-70889	26	12	of	of	ADP
bjp-70889	26	13	cancer	cancer	NOUN
bjp-70889	26	14	cells	cell	NOUN
bjp-70889	26	15	,	,	PUNCT
bjp-70889	26	16	including	include	VERB
bjp-70889	26	17	caski	caski	PROPN
bjp-70889	26	18	cells	cell	NOUN
bjp-70889	26	19	,	,	PUNCT
bjp-70889	26	20	hela	hela	PROPN
bjp-70889	26	21	cells	cell	NOUN
bjp-70889	26	22	,	,	PUNCT
bjp-70889	26	23	and	and	CCONJ
bjp-70889	26	24	mcf-7	mcf-7	NOUN
bjp-70889	26	25	cells	cell	NOUN
bjp-70889	26	26	in	in	ADP
bjp-70889	26	27	a	a	DET
bjp-70889	26	28	dose	dose	NOUN
bjp-70889	26	29	-	-	PUNCT
bjp-70889	26	30	dependent	dependent	ADJ
bjp-70889	26	31	manner	manner	NOUN
bjp-70889	26	32	(	(	PUNCT
bjp-70889	26	33	floriano	floriano	NOUN
bjp-70889	26	34	et	et	PROPN
bjp-70889	26	35	al	al	PROPN
bjp-70889	26	36	.	.	PROPN
bjp-70889	26	37	,	,	PUNCT
bjp-70889	26	38	2021	2021	NUM
bjp-70889	26	39	;	;	PUNCT
bjp-70889	26	40	li	li	PROPN
bjp-70889	26	41	et	et	PROPN
bjp-70889	26	42	al	al	PROPN
bjp-70889	26	43	.	.	PROPN
bjp-70889	26	44	,	,	PUNCT
bjp-70889	26	45	2023	2023	NUM
bjp-70889	26	46	)	)	PUNCT
bjp-70889	26	47	.	.	PUNCT
bjp-70889	27	1	moreover	moreover	ADV
bjp-70889	27	2	,	,	PUNCT
bjp-70889	27	3	modern	modern	ADJ
bjp-70889	27	4	pharmacological	pharmacological	ADJ
bjp-70889	27	5	studies	study	NOUN
bjp-70889	27	6	have	have	AUX
bjp-70889	27	7	revealed	reveal	VERB
bjp-70889	27	8	that	that	SCONJ
bjp-70889	27	9	berberine	berberine	NOUN
bjp-70889	27	10	possesses	possess	VERB
bjp-70889	27	11	antiviral	antiviral	ADJ
bjp-70889	27	12	properties	property	NOUN
bjp-70889	27	13	(	(	PUNCT
bjp-70889	27	14	kim	kim	PROPN
bjp-70889	27	15	et	et	PROPN
bjp-70889	27	16	al	al	PROPN
bjp-70889	27	17	.	.	PROPN
bjp-70889	27	18	,	,	PUNCT
bjp-70889	27	19	2016	2016	NUM
bjp-70889	27	20	)	)	PUNCT
bjp-70889	27	21	.	.	PUNCT
bjp-70889	28	1	berberine	berberine	PROPN
bjp-70889	28	2	can	can	AUX
bjp-70889	28	3	inhibit	inhibit	VERB
bjp-70889	28	4	the	the	DET
bjp-70889	28	5	replication	replication	NOUN
bjp-70889	28	6	of	of	ADP
bjp-70889	28	7	human	human	ADJ
bjp-70889	28	8	papillomavirus	papillomavirus	NOUN
bjp-70889	28	9	by	by	ADP
bjp-70889	28	10	down	down	ADV
bjp-70889	28	11	-	-	PUNCT
bjp-70889	28	12	regulating	regulate	VERB
bjp-70889	28	13	human	human	ADJ
bjp-70889	28	14	papillomavirus	papillomavirus	NOUN
bjp-70889	28	15	oncogenes	oncogene	NOUN
bjp-70889	28	16	expression	expression	NOUN
bjp-70889	28	17	(	(	PUNCT
bjp-70889	28	18	mahata	mahata	VERB
bjp-70889	28	19	et	et	PROPN
bjp-70889	28	20	al	al	PROPN
bjp-70889	28	21	.	.	PROPN
bjp-70889	28	22	,	,	PUNCT
bjp-70889	28	23	2011	2011	NUM
bjp-70889	28	24	)	)	PUNCT
bjp-70889	28	25	.	.	PUNCT
bjp-70889	29	1	therefore	therefore	ADV
bjp-70889	29	2	,	,	PUNCT
bjp-70889	29	3	berberine	berberine	NOUN
bjp-70889	29	4	emerges	emerge	VERB
bjp-70889	29	5	as	as	ADP
bjp-70889	29	6	a	a	DET
bjp-70889	29	7	potential	potential	ADJ
bjp-70889	29	8	candidate	candidate	NOUN
bjp-70889	29	9	for	for	ADP
bjp-70889	29	10	use	use	NOUN
bjp-70889	29	11	as	as	ADP
bjp-70889	29	12	an	an	DET
bjp-70889	29	13	antitumor	antitumor	PROPN
bjp-70889	29	14	and	and	CCONJ
bjp-70889	29	15	antiviral	antiviral	ADJ
bjp-70889	29	16	drug	drug	NOUN
bjp-70889	29	17	.	.	PUNCT
bjp-70889	30	1	multiple	multiple	ADJ
bjp-70889	30	2	studies	study	NOUN
bjp-70889	30	3	have	have	AUX
bjp-70889	30	4	identified	identify	VERB
bjp-70889	30	5	cell	cell	NOUN
bjp-70889	30	6	necrosis	necrosis	NOUN
bjp-70889	30	7	as	as	ADP
bjp-70889	30	8	a	a	DET
bjp-70889	30	9	regulated	regulated	ADJ
bjp-70889	30	10	cell	cell	NOUN
bjp-70889	30	11	death	death	NOUN
bjp-70889	30	12	mechanism	mechanism	NOUN
bjp-70889	30	13	known	know	VERB
bjp-70889	30	14	as	as	ADP
bjp-70889	30	15	necroptosis	necroptosis	NOUN
bjp-70889	30	16	(	(	PUNCT
bjp-70889	30	17	vanden	vanden	PROPN
bjp-70889	30	18	et	et	PROPN
bjp-70889	30	19	al	al	PROPN
bjp-70889	30	20	.	.	PROPN
bjp-70889	30	21	,	,	PUNCT
bjp-70889	30	22	2014	2014	NUM
bjp-70889	30	23	;	;	PUNCT
bjp-70889	30	24	bertheloot	bertheloot	NOUN
bjp-70889	30	25	et	et	PROPN
bjp-70889	30	26	al	al	PROPN
bjp-70889	30	27	.	.	PROPN
bjp-70889	30	28	,	,	PUNCT
bjp-70889	30	29	2021	2021	NUM
bjp-70889	30	30	;	;	PUNCT
bjp-70889	30	31	gao	gao	PROPN
bjp-70889	30	32	et	et	PROPN
bjp-70889	30	33	al	al	PROPN
bjp-70889	30	34	.	.	PROPN
bjp-70889	30	35	,	,	PUNCT
bjp-70889	30	36	2022	2022	NUM
bjp-70889	30	37	)	)	PUNCT
bjp-70889	30	38	.	.	PUNCT
bjp-70889	31	1	necroptosis	necroptosis	NOUN
bjp-70889	31	2	shares	share	NOUN
bjp-70889	31	3	similarities	similarity	NOUN
bjp-70889	31	4	with	with	ADP
bjp-70889	31	5	apoptosis	apoptosis	NOUN
bjp-70889	31	6	but	but	CCONJ
bjp-70889	31	7	exhibits	exhibit	VERB
bjp-70889	31	8	typical	typical	ADJ
bjp-70889	31	9	characteristics	characteristic	NOUN
bjp-70889	31	10	of	of	ADP
bjp-70889	31	11	cell	cell	NOUN
bjp-70889	31	12	necrosis	necrosis	NOUN
bjp-70889	31	13	,	,	PUNCT
bjp-70889	31	14	such	such	ADJ
bjp-70889	31	15	as	as	ADP
bjp-70889	31	16	organelle	organelle	NOUN
bjp-70889	31	17	swelling	swelling	NOUN
bjp-70889	31	18	,	,	PUNCT
bjp-70889	31	19	plasma	plasma	NOUN
bjp-70889	31	20	membrane	membrane	NOUN
bjp-70889	31	21	rupture	rupture	NOUN
bjp-70889	31	22	,	,	PUNCT
bjp-70889	31	23	and	and	CCONJ
bjp-70889	31	24	release	release	NOUN
bjp-70889	31	25	of	of	ADP
bjp-70889	31	26	cellular	cellular	ADJ
bjp-70889	31	27	contents	content	NOUN
bjp-70889	31	28	(	(	PUNCT
bjp-70889	31	29	bertheloot	bertheloot	NOUN
bjp-70889	31	30	et	et	PROPN
bjp-70889	31	31	al	al	PROPN
bjp-70889	31	32	.	.	PROPN
bjp-70889	31	33	,	,	PUNCT
bjp-70889	31	34	2021	2021	NUM
bjp-70889	31	35	;	;	PUNCT
bjp-70889	31	36	gao	gao	PROPN
bjp-70889	31	37	et	et	PROPN
bjp-70889	31	38	al	al	PROPN
bjp-70889	31	39	.	.	PROPN
bjp-70889	31	40	,	,	PUNCT
bjp-70889	31	41	2022	2022	NUM
bjp-70889	31	42	)	)	PUNCT
bjp-70889	31	43	.	.	PUNCT
bjp-70889	32	1	research	research	NOUN
bjp-70889	32	2	has	have	AUX
bjp-70889	32	3	shown	show	VERB
bjp-70889	32	4	that	that	SCONJ
bjp-70889	32	5	necroptosis	necroptosis	NOUN
bjp-70889	32	6	is	be	AUX
bjp-70889	32	7	involved	involve	VERB
bjp-70889	32	8	in	in	ADP
bjp-70889	32	9	processes	process	NOUN
bjp-70889	32	10	such	such	ADJ
bjp-70889	32	11	as	as	ADP
bjp-70889	32	12	anti	anti	ADJ
bjp-70889	32	13	-	-	ADJ
bjp-70889	32	14	tumor	tumor	ADJ
bjp-70889	32	15	and	and	CCONJ
bjp-70889	32	16	anti	anti	ADJ
bjp-70889	32	17	-	-	ADJ
bjp-70889	32	18	viral	viral	ADJ
bjp-70889	32	19	responses	response	NOUN
bjp-70889	32	20	(	(	PUNCT
bjp-70889	32	21	verdonck	verdonck	NOUN
bjp-70889	32	22	et	et	PROPN
bjp-70889	32	23	al	al	PROPN
bjp-70889	32	24	.	.	PROPN
bjp-70889	32	25	,	,	PUNCT
bjp-70889	32	26	2022	2022	NUM
bjp-70889	32	27	)	)	PUNCT
bjp-70889	32	28	.	.	PUNCT
bjp-70889	33	1	the	the	DET
bjp-70889	33	2	focus	focus	NOUN
bjp-70889	33	3	in	in	ADP
bjp-70889	33	4	prior	prior	ADJ
bjp-70889	33	5	anti	anti	ADJ
bjp-70889	33	6	-	-	ADJ
bjp-70889	33	7	tumor	tumor	ADJ
bjp-70889	33	8	research	research	NOUN
bjp-70889	33	9	has	have	AUX
bjp-70889	33	10	centered	center	VERB
bjp-70889	33	11	around	around	ADP
bjp-70889	33	12	apoptosis	apoptosis	NOUN
bjp-70889	33	13	.	.	PUNCT
bjp-70889	34	1	however	however	ADV
bjp-70889	34	2	,	,	PUNCT
bjp-70889	34	3	multiple	multiple	ADJ
bjp-70889	34	4	evidence	evidence	NOUN
bjp-70889	34	5	indicate	indicate	VERB
bjp-70889	34	6	that	that	SCONJ
bjp-70889	34	7	tumor	tumor	NOUN
bjp-70889	34	8	cells	cell	NOUN
bjp-70889	34	9	have	have	AUX
bjp-70889	34	10	evolved	evolve	VERB
bjp-70889	34	11	anti	anti	ADJ
bjp-70889	34	12	-apoptotic	-apoptotic	ADJ
bjp-70889	34	13	properties	property	NOUN
bjp-70889	34	14	,	,	PUNCT
bjp-70889	34	15	leading	lead	VERB
bjp-70889	34	16	to	to	ADP
bjp-70889	34	17	the	the	DET
bjp-70889	34	18	development	development	NOUN
bjp-70889	34	19	of	of	ADP
bjp-70889	34	20	drug	drug	NOUN
bjp-70889	34	21	resistance	resistance	NOUN
bjp-70889	34	22	through	through	ADP
bjp-70889	34	23	the	the	DET
bjp-70889	34	24	induction	induction	NOUN
bjp-70889	34	25	of	of	ADP
bjp-70889	34	26	apoptosis	apoptosis	NOUN
bjp-70889	34	27	defects	defect	NOUN
bjp-70889	34	28	.	.	PUNCT
bjp-70889	35	1	therefore	therefore	ADV
bjp-70889	35	2	,	,	PUNCT
bjp-70889	35	3	inducing	induce	VERB
bjp-70889	35	4	necroptosis	necroptosis	NOUN
bjp-70889	35	5	is	be	AUX
bjp-70889	35	6	antici	antici	NOUN
bjp-70889	35	7	pated	pated	ADJ
bjp-70889	35	8	to	to	PART
bjp-70889	35	9	be	be	AUX
bjp-70889	35	10	a	a	DET
bjp-70889	35	11	new	new	ADJ
bjp-70889	35	12	strategy	strategy	NOUN
bjp-70889	35	13	for	for	ADP
bjp-70889	35	14	overcoming	overcome	VERB
bjp-70889	35	15	apoptosis	apoptosis	NOUN
bjp-70889	35	16	resistance	resistance	NOUN
bjp-70889	35	17	and	and	CCONJ
bjp-70889	35	18	treating	treat	VERB
bjp-70889	35	19	cancer	cancer	NOUN
bjp-70889	35	20	(	(	PUNCT
bjp-70889	35	21	feoktistova	feoktistova	PROPN
bjp-70889	35	22	and	and	CCONJ
bjp-70889	35	23	leverkus	leverkus	PROPN
bjp-70889	35	24	,	,	PUNCT
bjp-70889	35	25	2015	2015	NUM
bjp-70889	35	26	;	;	PUNCT
bjp-70889	35	27	n	n	CCONJ
bjp-70889	35	28	et	et	PROPN
bjp-70889	35	29	al	al	PROPN
bjp-70889	35	30	.	.	PROPN
bjp-70889	35	31	,	,	PUNCT
bjp-70889	35	32	2021	2021	NUM
bjp-70889	35	33	)	)	PUNCT
bjp-70889	35	34	.	.	PUNCT
bjp-70889	36	1	receptor	receptor	NOUN
bjp-70889	36	2	-	-	PUNCT
bjp-70889	36	3	interacting	interact	VERB
bjp-70889	36	4	protein	protein	NOUN
bjp-70889	36	5	kinase	kinase	NOUN
bjp-70889	36	6	1	1	NUM
bjp-70889	36	7	(	(	PUNCT
bjp-70889	36	8	ripk1	ripk1	NOUN
bjp-70889	36	9	)	)	PUNCT
bjp-70889	36	10	is	be	AUX
bjp-70889	36	11	a	a	DET
bjp-70889	36	12	well	well	ADV
bjp-70889	36	13	-	-	PUNCT
bjp-70889	36	14	known	know	VERB
bjp-70889	36	15	serine	serine	NOUN
bjp-70889	36	16	/	/	SYM
bjp-70889	36	17	threonine	threonine	ADJ
bjp-70889	36	18	kinase	kinase	NOUN
bjp-70889	36	19	that	that	PRON
bjp-70889	36	20	plays	play	VERB
bjp-70889	36	21	a	a	DET
bjp-70889	36	22	pivotal	pivotal	ADJ
bjp-70889	36	23	role	role	NOUN
bjp-70889	36	24	in	in	ADP
bjp-70889	36	25	the	the	DET
bjp-70889	36	26	necroptotic	necroptotic	ADJ
bjp-70889	36	27	pathway	pathway	NOUN
bjp-70889	36	28	(	(	PUNCT
bjp-70889	36	29	kaczmarek	kaczmarek	PROPN
bjp-70889	36	30	et	et	PROPN
bjp-70889	36	31	al	al	PROPN
bjp-70889	36	32	.	.	PROPN
bjp-70889	36	33	,	,	PUNCT
bjp-70889	36	34	2013	2013	NUM
bjp-70889	36	35	)	)	PUNCT
bjp-70889	36	36	.	.	PUNCT
bjp-70889	37	1	tnf	tnf	PROPN
bjp-70889	37	2	-	-	PUNCT
bjp-70889	37	3	α	α	PROPN
bjp-70889	37	4	(	(	PUNCT
bjp-70889	37	5	one	one	NUM
bjp-70889	37	6	of	of	ADP
bjp-70889	37	7	the	the	DET
bjp-70889	37	8	promoter	promoter	NOUN
bjp-70889	37	9	factors	factor	NOUN
bjp-70889	37	10	)	)	PUNCT
bjp-70889	37	11	binds	bind	VERB
bjp-70889	37	12	to	to	ADP
bjp-70889	37	13	the	the	DET
bjp-70889	37	14	specific	specific	ADJ
bjp-70889	37	15	receptor	receptor	NOUN
bjp-70889	37	16	on	on	ADP
bjp-70889	37	17	the	the	DET
bjp-70889	37	18	cell	cell	NOUN
bjp-70889	37	19	membrane	membrane	NOUN
bjp-70889	37	20	to	to	PART
bjp-70889	37	21	initiate	initiate	VERB
bjp-70889	37	22	necroptosis	necroptosis	NOUN
bjp-70889	37	23	,	,	PUNCT
bjp-70889	37	24	and	and	CCONJ
bjp-70889	37	25	ripk1	ripk1	NOUN
bjp-70889	37	26	activates	activate	VERB
bjp-70889	37	27	and	and	CCONJ
bjp-70889	37	28	recruits	recruit	VERB
bjp-70889	37	29	ripk3	ripk3	NOUN
bjp-70889	37	30	,	,	PUNCT
bjp-70889	37	31	leading	lead	VERB
bjp-70889	37	32	to	to	ADP
bjp-70889	37	33	the	the	DET
bjp-70889	37	34	activation	activation	NOUN
bjp-70889	37	35	of	of	ADP
bjp-70889	37	36	the	the	DET
bjp-70889	37	37	effector	effector	NOUN
bjp-70889	37	38	protein	protein	NOUN
bjp-70889	37	39	mixed	mix	VERB
bjp-70889	37	40	lineage	lineage	NOUN
bjp-70889	37	41	kinase	kinase	NOUN
bjp-70889	37	42	domain	domain	NOUN
bjp-70889	37	43	-	-	PUNCT
bjp-70889	37	44	like	like	ADJ
bjp-70889	37	45	protein	protein	NOUN
bjp-70889	37	46	(	(	PUNCT
bjp-70889	37	47	mlkl	mlkl	PROPN
bjp-70889	37	48	)	)	PUNCT
bjp-70889	37	49	.	.	PUNCT
bjp-70889	38	1	phosphorylated	phosphorylate	VERB
bjp-70889	38	2	mlkl	mlkl	PROPN
bjp-70889	38	3	then	then	ADV
bjp-70889	38	4	oligomerizes	oligomerize	VERB
bjp-70889	38	5	at	at	ADP
bjp-70889	38	6	the	the	DET
bjp-70889	38	7	cell	cell	NOUN
bjp-70889	38	8	membrane	membrane	NOUN
bjp-70889	38	9	,	,	PUNCT
bjp-70889	38	10	causing	cause	VERB
bjp-70889	38	11	the	the	DET
bjp-70889	38	12	formation	formation	NOUN
bjp-70889	38	13	of	of	ADP
bjp-70889	38	14	pores	pore	NOUN
bjp-70889	38	15	and	and	CCONJ
bjp-70889	38	16	loss	loss	NOUN
bjp-70889	38	17	of	of	ADP
bjp-70889	38	18	membrane	membrane	NOUN
bjp-70889	38	19	integrity	integrity	NOUN
bjp-70889	38	20	,	,	PUNCT
bjp-70889	38	21	ultimately	ultimately	ADV
bjp-70889	38	22	resulting	result	VERB
bjp-70889	38	23	in	in	ADP
bjp-70889	38	24	cell	cell	NOUN
bjp-70889	38	25	death	death	NOUN
bjp-70889	38	26	(	(	PUNCT
bjp-70889	38	27	bertheloot	bertheloot	PROPN
bjp-70889	38	28	et	et	PROPN
bjp-70889	38	29	al	al	PROPN
bjp-70889	38	30	.	.	PROPN
bjp-70889	38	31	,	,	PUNCT
bjp-70889	38	32	2021	2021	NUM
bjp-70889	38	33	;	;	PUNCT
bjp-70889	38	34	chen	chen	PROPN
bjp-70889	38	35	et	et	PROPN
bjp-70889	38	36	al	al	PROPN
bjp-70889	38	37	.	.	PROPN
bjp-70889	38	38	,	,	PUNCT
bjp-70889	38	39	2019	2019	NUM
bjp-70889	38	40	;	;	PUNCT
bjp-70889	38	41	gao	gao	PROPN
bjp-70889	38	42	et	et	PROPN
bjp-70889	38	43	al	al	PROPN
bjp-70889	38	44	.	.	PROPN
bjp-70889	38	45	,	,	PUNCT
bjp-70889	38	46	2022	2022	NUM
bjp-70889	38	47	)	)	PUNCT
bjp-70889	38	48	.	.	PUNCT
bjp-70889	39	1	preliminary	preliminary	ADJ
bjp-70889	39	2	experiments	experiment	NOUN
bjp-70889	39	3	of	of	ADP
bjp-70889	39	4	the	the	DET
bjp-70889	39	5	research	research	NOUN
bjp-70889	39	6	group	group	NOUN
bjp-70889	39	7	have	have	AUX
bjp-70889	39	8	revealed	reveal	VERB
bjp-70889	39	9	that	that	SCONJ
bjp-70889	39	10	berberine	berberine	NOUN
bjp-70889	39	11	can	can	AUX
bjp-70889	39	12	inhibit	inhibit	VERB
bjp-70889	39	13	the	the	DET
bjp-70889	39	14	proliferation	proliferation	NOUN
bjp-70889	39	15	of	of	ADP
bjp-70889	39	16	h8	h8	PROPN
bjp-70889	39	17	cervical	cervical	ADJ
bjp-70889	39	18	cells	cell	NOUN
bjp-70889	39	19	,	,	PUNCT
bjp-70889	39	20	indicating	indicate	VERB
bjp-70889	39	21	its	its	PRON
bjp-70889	39	22	potential	potential	NOUN
bjp-70889	39	23	in	in	ADP
bjp-70889	39	24	the	the	DET
bjp-70889	39	25	treatment	treatment	NOUN
bjp-70889	39	26	of	of	ADP
bjp-70889	39	27	cervical	cervical	ADJ
bjp-70889	39	28	intraepithelial	intraepithelial	ADJ
bjp-70889	39	29	neoplasia	neoplasia	NOUN
bjp-70889	39	30	.	.	PUNCT
bjp-70889	40	1	building	build	VERB
bjp-70889	40	2	upon	upon	SCONJ
bjp-70889	40	3	these	these	DET
bjp-70889	40	4	promising	promising	ADJ
bjp-70889	40	5	findings	finding	NOUN
bjp-70889	40	6	,	,	PUNCT
bjp-70889	40	7	the	the	DET
bjp-70889	40	8	present	present	ADJ
bjp-70889	40	9	study	study	NOUN
bjp-70889	40	10	aims	aim	VERB
bjp-70889	40	11	to	to	PART
bjp-70889	40	12	delve	delve	VERB
bjp-70889	40	13	into	into	ADP
bjp-70889	40	14	the	the	DET
bjp-70889	40	15	mechanisms	mechanism	NOUN
bjp-70889	40	16	underlying	underlie	VERB
bjp-70889	40	17	berberine	berberine	NOUN
bjp-70889	40	18	-	-	PUNCT
bjp-70889	40	19	induced	induce	VERB
bjp-70889	40	20	cell	cell	NOUN
bjp-70889	40	21	death	death	NOUN
bjp-70889	40	22	in	in	ADP
bjp-70889	40	23	h8	h8	PROPN
bjp-70889	40	24	cells	cell	NOUN
bjp-70889	40	25	.	.	PUNCT
bjp-70889	41	1	the	the	DET
bjp-70889	41	2	ultimate	ultimate	ADJ
bjp-70889	41	3	objective	objective	NOUN
bjp-70889	41	4	is	be	AUX
bjp-70889	41	5	to	to	PART
bjp-70889	41	6	unveil	unveil	VERB
bjp-70889	41	7	novel	novel	ADJ
bjp-70889	41	8	therapeutic	therapeutic	ADJ
bjp-70889	41	9	strategies	strategy	NOUN
bjp-70889	41	10	for	for	ADP
bjp-70889	41	11	the	the	DET
bjp-70889	41	12	prevention	prevention	NOUN
bjp-70889	41	13	and	and	CCONJ
bjp-70889	41	14	treatment	treatment	NOUN
bjp-70889	41	15	of	of	ADP
bjp-70889	41	16	cervical	cervical	ADJ
bjp-70889	41	17	intraepithelial	intraepithelial	ADJ
bjp-70889	41	18	neoplasia	neoplasia	NOUN
bjp-70889	41	19	.	.	PUNCT
bjp-70889	42	1	materials	material	NOUN
bjp-70889	42	2	and	and	CCONJ
bjp-70889	42	3	methods	method	NOUN
bjp-70889	42	4	cell	cell	NOUN
bjp-70889	42	5	culture	culture	NOUN
bjp-70889	42	6	human	human	ADJ
bjp-70889	42	7	immortalized	immortalize	VERB
bjp-70889	42	8	cervical	cervical	ADJ
bjp-70889	42	9	squamous	squamous	ADJ
bjp-70889	42	10	epithelial	epithelial	ADJ
bjp-70889	42	11	cell	cell	NOUN
bjp-70889	42	12	line	line	NOUN
bjp-70889	42	13	(	(	PUNCT
bjp-70889	42	14	h8	h8	PROPN
bjp-70889	42	15	)	)	PUNCT
bjp-70889	42	16	was	be	AUX
bjp-70889	42	17	obtained	obtain	VERB
bjp-70889	42	18	from	from	ADP
bjp-70889	42	19	the	the	DET
bjp-70889	42	20	guangxi	guangxi	PROPN
bjp-70889	42	21	medical	medical	PROPN
bjp-70889	42	22	university	university	PROPN
bjp-70889	42	23	in	in	ADP
bjp-70889	42	24	china	china	PROPN
bjp-70889	42	25	.	.	PUNCT
bjp-70889	43	1	the	the	DET
bjp-70889	43	2	h8	h8	PROPN
bjp-70889	43	3	cells	cell	NOUN
bjp-70889	43	4	were	be	AUX
bjp-70889	43	5	infected	infect	VERB
bjp-70889	43	6	with	with	ADP
bjp-70889	43	7	hpv16	hpv16	NOUN
bjp-70889	43	8	to	to	PART
bjp-70889	43	9	represent	represent	VERB
bjp-70889	43	10	cervical	cervical	ADJ
bjp-70889	43	11	intraepithelial	intraepithelial	ADJ
bjp-70889	43	12	neoplasia	neoplasia	ADJ
bjp-70889	43	13	ii	ii	PROPN
bjp-70889	43	14	-	-	PUNCT
bjp-70889	43	15	iii	iii	NUM
bjp-70889	43	16	levels	level	NOUN
bjp-70889	43	17	.	.	PUNCT
bjp-70889	44	1	h8	h8	PROPN
bjp-70889	44	2	cells	cell	NOUN
bjp-70889	44	3	were	be	AUX
bjp-70889	44	4	maintained	maintain	VERB
bjp-70889	44	5	in	in	ADP
bjp-70889	44	6	rpmi	rpmi	NOUN
bjp-70889	44	7	1640	1640	NUM
bjp-70889	44	8	medium	medium	NOUN
bjp-70889	44	9	supplemented	supplement	VERB
bjp-70889	44	10	with	with	ADP
bjp-70889	44	11	10%fetal	10%fetal	NUM
bjp-70889	44	12	bovine	bovine	NOUN
bjp-70889	44	13	serum	serum	NOUN
bjp-70889	44	14	(	(	PUNCT
bjp-70889	44	15	bdbio	bdbio	NOUN
bjp-70889	44	16	,	,	PUNCT
bjp-70889	44	17	china	china	PROPN
bjp-70889	44	18	)	)	PUNCT
bjp-70889	44	19	,	,	PUNCT
bjp-70889	44	20	1%penicillin	1%penicillin	NUM
bjp-70889	44	21	,	,	PUNCT
bjp-70889	44	22	and	and	CCONJ
bjp-70889	44	23	streptomycin	streptomycin	PROPN
bjp-70889	44	24	.	.	PUNCT
bjp-70889	45	1	the	the	DET
bjp-70889	45	2	cells	cell	NOUN
bjp-70889	45	3	were	be	AUX
bjp-70889	45	4	incubated	incubate	VERB
bjp-70889	45	5	at	at	ADP
bjp-70889	45	6	37	37	NUM
bjp-70889	45	7	°	°	ADP
bjp-70889	45	8	c	c	NOUN
bjp-70889	45	9	in	in	ADP
bjp-70889	45	10	a	a	DET
bjp-70889	45	11	5%co2	5%co2	NUM
bjp-70889	45	12	atmosphere	atmosphere	NOUN
bjp-70889	45	13	until	until	ADP
bjp-70889	45	14	reaching	reach	VERB
bjp-70889	45	15	approximately	approximately	ADV
bjp-70889	45	16	80%confluence	80%confluence	NOUN
bjp-70889	45	17	.	.	PUNCT
bjp-70889	46	1	cell	cell	NOUN
bjp-70889	46	2	freezing	freezing	NOUN
bjp-70889	46	3	and	and	CCONJ
bjp-70889	46	4	passaging	passaging	NOUN
bjp-70889	46	5	were	be	AUX
bjp-70889	46	6	performed	perform	VERB
bjp-70889	46	7	at	at	ADP
bjp-70889	46	8	this	this	DET
bjp-70889	46	9	stage	stage	NOUN
bjp-70889	46	10	,	,	PUNCT
bjp-70889	46	11	and	and	CCONJ
bjp-70889	46	12	cells	cell	NOUN
bjp-70889	46	13	in	in	ADP
bjp-70889	46	14	the	the	DET
bjp-70889	46	15	logarithmic	logarithmic	ADJ
bjp-70889	46	16	growth	growth	NOUN
bjp-70889	46	17	phase	phase	NOUN
bjp-70889	46	18	were	be	AUX
bjp-70889	46	19	used	use	VERB
bjp-70889	46	20	for	for	ADP
bjp-70889	46	21	subsequent	subsequent	ADJ
bjp-70889	46	22	experiments	experiment	NOUN
bjp-70889	46	23	.	.	PUNCT
bjp-70889	47	1	notably	notably	ADV
bjp-70889	47	2	,	,	PUNCT
bjp-70889	47	3	cells	cell	NOUN
bjp-70889	47	4	were	be	AUX
bjp-70889	47	5	passaged	passage	VERB
bjp-70889	47	6	for	for	ADP
bjp-70889	47	7	no	no	DET
bjp-70889	47	8	more	more	ADJ
bjp-70889	47	9	than	than	ADP
bjp-70889	47	10	10	10	NUM
bjp-70889	47	11	times	time	NOUN
bjp-70889	47	12	in	in	ADP
bjp-70889	47	13	this	this	DET
bjp-70889	47	14	study	study	NOUN
bjp-70889	47	15	.	.	PUNCT
bjp-70889	48	1	culture	culture	NOUN
bjp-70889	48	2	flasks	flask	NOUN
bjp-70889	48	3	and	and	CCONJ
bjp-70889	48	4	plates	plate	NOUN
bjp-70889	48	5	were	be	AUX
bjp-70889	48	6	purchased	purchase	VERB
bjp-70889	48	7	from	from	ADP
bjp-70889	48	8	nest	nest	NOUN
bjp-70889	48	9	biotechnology	biotechnology	NOUN
bjp-70889	48	10	.	.	PUNCT
bjp-70889	49	1	drug	drug	NOUN
bjp-70889	49	2	intervention	intervention	PROPN
bjp-70889	49	3	berberine	berberine	NOUN
bjp-70889	49	4	(	(	PUNCT
bjp-70889	49	5	2086	2086	NUM
bjp-70889	49	6	-	-	SYM
bjp-70889	49	7	83	83	NUM
bjp-70889	49	8	-	-	SYM
bjp-70889	49	9	1	1	NUM
bjp-70889	49	10	,	,	PUNCT
bjp-70889	49	11	aladdin	aladdin	NOUN
bjp-70889	49	12	,	,	PUNCT
bjp-70889	49	13	china	china	PROPN
bjp-70889	49	14	)	)	PUNCT
bjp-70889	49	15	was	be	AUX
bjp-70889	49	16	prepared	prepare	VERB
bjp-70889	49	17	as	as	ADP
bjp-70889	49	18	a	a	DET
bjp-70889	49	19	solution	solution	NOUN
bjp-70889	49	20	(	(	PUNCT
bjp-70889	49	21	100	100	NUM
bjp-70889	49	22	mm	mm	NOUN
bjp-70889	49	23	)	)	PUNCT
bjp-70889	49	24	using	use	VERB
bjp-70889	49	25	dmso	dmso	NOUN
bjp-70889	49	26	as	as	ADP
bjp-70889	49	27	a	a	DET
bjp-70889	49	28	solvent	solvent	NOUN
bjp-70889	49	29	,	,	PUNCT
bjp-70889	49	30	facilitated	facilitate	VERB
bjp-70889	49	31	by	by	ADP
bjp-70889	49	32	ultrasound	ultrasound	NOUN
bjp-70889	49	33	,	,	PUNCT
bjp-70889	49	34	and	and	CCONJ
bjp-70889	49	35	stored	store	VERB
bjp-70889	49	36	at	at	ADP
bjp-70889	49	37	-20	-20	PROPN
bjp-70889	49	38	℃	℃	PROPN
bjp-70889	49	39	.	.	PROPN
bjp-70889	49	40	subsequently	subsequently	ADV
bjp-70889	49	41	,	,	PUNCT
bjp-70889	49	42	the	the	DET
bjp-70889	49	43	medium	medium	NOUN
bjp-70889	49	44	was	be	AUX
bjp-70889	49	45	adequately	adequately	ADV
bjp-70889	49	46	diluted	dilute	VERB
bjp-70889	49	47	to	to	ADP
bjp-70889	49	48	the	the	DET
bjp-70889	49	49	desired	desire	VERB
bjp-70889	49	50	concentration	concentration	NOUN
bjp-70889	49	51	so	so	ADV
bjp-70889	49	52	,	,	PUNCT
bjp-70889	49	53	ensuring	ensure	VERB
bjp-70889	49	54	that	that	SCONJ
bjp-70889	49	55	the	the	DET
bjp-70889	49	56	dmso	dmso	ADJ
bjp-70889	49	57	concentration	concentration	NOUN
bjp-70889	49	58	did	do	AUX
bjp-70889	49	59	not	not	PART
bjp-70889	49	60	exceed	exceed	VERB
bjp-70889	49	61	1/1,000	1/1,000	NUM
bjp-70889	49	62	.	.	PUNCT
bjp-70889	49	63	nec-1	nec-1	PRON
bjp-70889	49	64	(	(	PUNCT
bjp-70889	49	65	4311	4311	NUM
bjp-70889	49	66	-	-	SYM
bjp-70889	49	67	88	88	NUM
bjp-70889	49	68	-	-	SYM
bjp-70889	49	69	0	0	NUM
bjp-70889	49	70	,	,	PUNCT
bjp-70889	49	71	aladdin	aladdin	NOUN
bjp-70889	49	72	,	,	PUNCT
bjp-70889	49	73	china	china	PROPN
bjp-70889	49	74	)	)	PUNCT
bjp-70889	49	75	was	be	AUX
bjp-70889	49	76	formulated	formulate	VERB
bjp-70889	49	77	into	into	ADP
bjp-70889	49	78	a	a	DET
bjp-70889	49	79	solution	solution	NOUN
bjp-70889	49	80	(	(	PUNCT
bjp-70889	49	81	10	10	NUM
bjp-70889	49	82	mm	mm	NOUN
bjp-70889	49	83	/	/	SYM
bjp-70889	49	84	l	l	NOUN
bjp-70889	49	85	)	)	PUNCT
bjp-70889	49	86	using	use	VERB
bjp-70889	49	87	dmso	dmso	NOUN
bjp-70889	49	88	as	as	ADP
bjp-70889	49	89	a	a	DET
bjp-70889	49	90	solvent	solvent	NOUN
bjp-70889	49	91	,	,	PUNCT
bjp-70889	49	92	assisted	assist	VERB
bjp-70889	49	93	by	by	ADP
bjp-70889	49	94	ultrasound	ultrasound	NOUN
bjp-70889	49	95	,	,	PUNCT
bjp-70889	49	96	and	and	CCONJ
bjp-70889	49	97	stored	store	VERB
bjp-70889	49	98	at	at	ADP
bjp-70889	49	99	-20	-20	PROPN
bjp-70889	49	100	℃	℃	PROPN
bjp-70889	49	101	.	.	PUNCT
bjp-70889	50	1	this	this	PRON
bjp-70889	50	2	was	be	AUX
bjp-70889	50	3	followed	follow	VERB
bjp-70889	50	4	by	by	ADP
bjp-70889	50	5	complete	complete	ADJ
bjp-70889	50	6	medium	medium	ADJ
bjp-70889	50	7	dilution	dilution	NOUN
bjp-70889	50	8	to	to	ADP
bjp-70889	50	9	2.5	2.5	NUM
bjp-70889	50	10	μm	μm	NOUN
bjp-70889	50	11	,	,	PUNCT
bjp-70889	50	12	ensuring	ensure	VERB
bjp-70889	50	13	that	that	SCONJ
bjp-70889	50	14	the	the	DET
bjp-70889	50	15	dmso	dmso	ADJ
bjp-70889	50	16	concentration	concentration	NOUN
bjp-70889	50	17	did	do	AUX
bjp-70889	50	18	not	not	PART
bjp-70889	50	19	exceed	exceed	VERB
bjp-70889	50	20	1/1,000	1/1,000	NUM
bjp-70889	50	21	.	.	PUNCT
bjp-70889	51	1	cell	cell	NOUN
bjp-70889	51	2	proliferation	proliferation	NOUN
bjp-70889	51	3	assay	assay	VERB
bjp-70889	51	4	the	the	DET
bjp-70889	51	5	impact	impact	NOUN
bjp-70889	51	6	of	of	ADP
bjp-70889	51	7	berberine	berberine	NOUN
bjp-70889	51	8	on	on	ADP
bjp-70889	51	9	the	the	DET
bjp-70889	51	10	viability	viability	NOUN
bjp-70889	51	11	of	of	ADP
bjp-70889	51	12	h8	h8	PROPN
bjp-70889	51	13	cells	cell	NOUN
bjp-70889	51	14	was	be	AUX
bjp-70889	51	15	assessed	assess	VERB
bjp-70889	51	16	through	through	ADP
bjp-70889	51	17	the	the	DET
bjp-70889	51	18	cck-8	cck-8	PUNCT
bjp-70889	51	19	assay	assay	NOUN
bjp-70889	51	20	.	.	PUNCT
bjp-70889	52	1	the	the	DET
bjp-70889	52	2	cell	cell	NOUN
bjp-70889	52	3	proliferation	proliferation	NOUN
bjp-70889	52	4	experiment	experiment	NOUN
bjp-70889	52	5	was	be	AUX
bjp-70889	52	6	conducted	conduct	VERB
bjp-70889	52	7	using	use	VERB
bjp-70889	52	8	the	the	DET
bjp-70889	52	9	cck-8	cck-8	PUNCT
bjp-70889	52	10	assay	assay	NOUN
bjp-70889	52	11	kit	kit	NOUN
bjp-70889	52	12	(	(	PUNCT
bjp-70889	52	13	medicalbio	medicalbio	ADJ
bjp-70889	52	14	,	,	PUNCT
bjp-70889	52	15	cck-08	cck-08	NOUN
bjp-70889	52	16	)	)	PUNCT
bjp-70889	52	17	.	.	PUNCT
bjp-70889	53	1	a	a	DET
bjp-70889	53	2	96	96	NUM
bjp-70889	53	3	-	-	PUNCT
bjp-70889	53	4	well	well	NOUN
bjp-70889	53	5	plate	plate	NOUN
bjp-70889	53	6	was	be	AUX
bjp-70889	53	7	prepared	prepare	VERB
bjp-70889	53	8	with	with	ADP
bjp-70889	53	9	100	100	NUM
bjp-70889	53	10	μl	μl	ADP
bjp-70889	53	11	of	of	ADP
bjp-70889	53	12	cell	cell	NOUN
bjp-70889	53	13	suspension	suspension	NOUN
bjp-70889	53	14	(	(	PUNCT
bjp-70889	53	15	1,000	1,000	NUM
bjp-70889	53	16	cells	cell	NOUN
bjp-70889	53	17	/	/	SYM
bjp-70889	53	18	well	well	ADV
bjp-70889	53	19	)	)	PUNCT
bjp-70889	53	20	and	and	CCONJ
bjp-70889	53	21	incubated	incubate	VERB
bjp-70889	53	22	in	in	ADP
bjp-70889	53	23	a	a	DET
bjp-70889	53	24	cell	cell	NOUN
bjp-70889	53	25	culture	culture	NOUN
bjp-70889	53	26	incubator	incubator	NOUN
bjp-70889	53	27	at	at	ADP
bjp-70889	53	28	37	37	NUM
bjp-70889	53	29	°	°	ADP
bjp-70889	53	30	c	c	NOUN
bjp-70889	53	31	with	with	ADP
bjp-70889	53	32	5%co	5%co	ADJ
bjp-70889	53	33	2	2	NUM
bjp-70889	53	34	for	for	ADP
bjp-70889	53	35	24	24	NUM
bjp-70889	53	36	hours	hour	NOUN
bjp-70889	53	37	.	.	PUNCT
bjp-70889	54	1	to	to	PART
bjp-70889	54	2	prevent	prevent	VERB
bjp-70889	54	3	evaporation	evaporation	NOUN
bjp-70889	54	4	at	at	ADP
bjp-70889	54	5	the	the	DET
bjp-70889	54	6	plate	plate	NOUN
bjp-70889	54	7	edges	edge	NOUN
bjp-70889	54	8	,	,	PUNCT
bjp-70889	54	9	pbs	pbs	PROPN
bjp-70889	54	10	buffer	buffer	NOUN
bjp-70889	54	11	was	be	AUX
bjp-70889	54	12	added	add	VERB
bjp-70889	54	13	around	around	ADP
bjp-70889	54	14	the	the	DET
bjp-70889	54	15	periphery	periphery	NOUN
bjp-70889	54	16	of	of	ADP
bjp-70889	54	17	the	the	DET
bjp-70889	54	18	24	24	NUM
bjp-70889	54	19	-	-	PUNCT
bjp-70889	54	20	hour	hour	NOUN
bjp-70889	54	21	incubation	incubation	NOUN
bjp-70889	54	22	,	,	PUNCT
bjp-70889	54	23	the	the	DET
bjp-70889	54	24	culture	culture	NOUN
bjp-70889	54	25	medium	medium	NOUN
bjp-70889	54	26	was	be	AUX
bjp-70889	54	27	aspirated	aspirate	VERB
bjp-70889	54	28	,	,	PUNCT
bjp-70889	54	29	and	and	CCONJ
bjp-70889	54	30	wells	well	NOUN
bjp-70889	54	31	were	be	AUX
bjp-70889	54	32	treated	treat	VERB
bjp-70889	54	33	with	with	ADP
bjp-70889	54	34	varying	vary	VERB
bjp-70889	54	35	concentrations	concentration	NOUN
bjp-70889	54	36	of	of	ADP
bjp-70889	54	37	the	the	DET
bjp-70889	54	38	drug	drug	NOUN
bjp-70889	54	39	-	-	PUNCT
bjp-70889	54	40	containing	contain	VERB
bjp-70889	54	41	medium	medium	ADJ
bjp-70889	54	42	(	(	PUNCT
bjp-70889	54	43	final	final	ADJ
bjp-70889	54	44	concentrations	concentration	NOUN
bjp-70889	54	45	of	of	ADP
bjp-70889	54	46	20	20	NUM
bjp-70889	54	47	,	,	PUNCT
bjp-70889	54	48	40	40	NUM
bjp-70889	54	49	,	,	PUNCT
bjp-70889	54	50	60	60	NUM
bjp-70889	54	51	,	,	PUNCT
bjp-70889	54	52	80	80	NUM
bjp-70889	54	53	,	,	PUNCT
bjp-70889	54	54	and	and	CCONJ
bjp-70889	54	55	100	100	NUM
bjp-70889	54	56	μm	μm	NUM
bjp-70889	54	57	)	)	PUNCT
bjp-70889	54	58	in	in	ADP
bjp-70889	54	59	respective	respective	ADJ
bjp-70889	54	60	experimental	experimental	ADJ
bjp-70889	54	61	wells	well	NOUN
bjp-70889	54	62	.	.	PUNCT
bjp-70889	55	1	the	the	DET
bjp-70889	55	2	control	control	NOUN
bjp-70889	55	3	group	group	NOUN
bjp-70889	55	4	was	be	AUX
bjp-70889	55	5	treated	treat	VERB
bjp-70889	55	6	with	with	ADP
bjp-70889	55	7	an	an	DET
bjp-70889	55	8	equal	equal	ADJ
bjp-70889	55	9	volume	volume	NOUN
bjp-70889	55	10	of	of	ADP
bjp-70889	55	11	medium	medium	ADJ
bjp-70889	55	12	containing	contain	VERB
bjp-70889	55	13	dmso	dmso	NOUN
bjp-70889	55	14	at	at	ADP
bjp-70889	55	15	a	a	DET
bjp-70889	55	16	concentration	concentration	NOUN
bjp-70889	55	17	not	not	PART
bjp-70889	55	18	exceeding	exceed	VERB
bjp-70889	55	19	one	one	NUM
bjp-70889	55	20	thousandth	thousandth	ADJ
bjp-70889	55	21	.	.	PUNCT
bjp-70889	56	1	cells	cell	NOUN
bjp-70889	56	2	were	be	AUX
bjp-70889	56	3	then	then	ADV
bjp-70889	56	4	incubated	incubate	VERB
bjp-70889	56	5	for	for	ADP
bjp-70889	56	6	additional	additional	ADJ
bjp-70889	56	7	24	24	NUM
bjp-70889	56	8	,	,	PUNCT
bjp-70889	56	9	48	48	NUM
bjp-70889	56	10	,	,	PUNCT
bjp-70889	56	11	and	and	CCONJ
bjp-70889	56	12	72	72	NUM
bjp-70889	56	13	hours	hour	NOUN
bjp-70889	56	14	.	.	PUNCT
bjp-70889	57	1	after	after	ADP
bjp-70889	57	2	proper	proper	ADJ
bjp-70889	57	3	incubation	incubation	NOUN
bjp-70889	57	4	in	in	ADP
bjp-70889	57	5	the	the	DET
bjp-70889	57	6	96	96	NUM
bjp-70889	57	7	-	-	PUNCT
bjp-70889	57	8	well	well	NOUN
bjp-70889	57	9	plate	plate	NOUN
bjp-70889	57	10	,	,	PUNCT
bjp-70889	57	11	the	the	DET
bjp-70889	57	12	culture	culture	NOUN
bjp-70889	57	13	medium	medium	NOUN
bjp-70889	57	14	was	be	AUX
bjp-70889	57	15	aspirated	aspirate	VERB
bjp-70889	57	16	,	,	PUNCT
bjp-70889	57	17	and	and	CCONJ
bjp-70889	57	18	100	100	NUM
bjp-70889	57	19	μl	μl	ADP
bjp-70889	57	20	of	of	ADP
bjp-70889	57	21	10%cck-8	10%cck-8	NUM
bjp-70889	57	22	solution	solution	NOUN
bjp-70889	57	23	was	be	AUX
bjp-70889	57	24	added	add	VERB
bjp-70889	57	25	to	to	ADP
bjp-70889	57	26	the	the	DET
bjp-70889	57	27	corresponding	corresponding	PROPN
bjp-70889	57	28	experi	experi	PROPN
bjp-70889	57	29	mental	mental	ADJ
bjp-70889	57	30	wells	wells	PROPN
bjp-70889	57	31	,	,	PUNCT
bjp-70889	57	32	followed	follow	VERB
bjp-70889	57	33	by	by	ADP
bjp-70889	57	34	an	an	DET
bjp-70889	57	35	incubator	incubator	NOUN
bjp-70889	57	36	for	for	ADP
bjp-70889	57	37	1	1	NUM
bjp-70889	57	38	hour	hour	NOUN
bjp-70889	57	39	.	.	PUNCT
bjp-70889	58	1	subsequently	subsequently	ADV
bjp-70889	58	2	,	,	PUNCT
bjp-70889	58	3	the	the	DET
bjp-70889	58	4	absorbance	absorbance	NOUN
bjp-70889	58	5	of	of	ADP
bjp-70889	58	6	each	each	DET
bjp-70889	58	7	well	well	ADV
bjp-70889	58	8	was	be	AUX
bjp-70889	58	9	measured	measure	VERB
bjp-70889	58	10	using	use	VERB
bjp-70889	58	11	an	an	DET
bjp-70889	58	12	enzyme	enzyme	NOUN
bjp-70889	58	13	labeling	labeling	NOUN
bjp-70889	58	14	instrument	instrument	NOUN
bjp-70889	58	15	set	set	VERB
bjp-70889	58	16	at	at	ADP
bjp-70889	58	17	a	a	DET
bjp-70889	58	18	wavelength	wavelength	NOUN
bjp-70889	58	19	of	of	ADP
bjp-70889	58	20	450	450	NUM
bjp-70889	58	21	nm	nm	NOUN
bjp-70889	58	22	(	(	PUNCT
bjp-70889	58	23	liu	liu	PROPN
bjp-70889	58	24	et	et	PROPN
bjp-70889	58	25	al	al	PROPN
bjp-70889	58	26	.	.	PROPN
bjp-70889	58	27	,	,	PUNCT
bjp-70889	58	28	2019	2019	NUM
bjp-70889	58	29	)	)	PUNCT
bjp-70889	58	30	.	.	PUNCT
bjp-70889	59	1	14	14	NUM
bjp-70889	59	2	bangladesh	bangladesh	PROPN
bjp-70889	59	3	j	j	PROPN
bjp-70889	59	4	pharmacol	pharmacol	PROPN
bjp-70889	59	5	2024	2024	NUM
bjp-70889	59	6	;	;	PUNCT
bjp-70889	59	7	19	19	NUM
bjp-70889	59	8	:	:	SYM
bjp-70889	59	9	13	13	NUM
bjp-70889	59	10	-	-	SYM
bjp-70889	59	11	22	22	NUM
bjp-70889	59	12	quantitative	quantitative	ADJ
bjp-70889	59	13	real	real	ADJ
bjp-70889	59	14	-	-	PUNCT
bjp-70889	59	15	time	time	NOUN
bjp-70889	59	16	polymerase	polymerase	NOUN
bjp-70889	59	17	chain	chain	NOUN
bjp-70889	59	18	reaction	reaction	NOUN
bjp-70889	59	19	(	(	PUNCT
bjp-70889	59	20	qrt	qrt	NOUN
bjp-70889	59	21	-	-	PUNCT
bjp-70889	59	22	pcr	pcr	NOUN
bjp-70889	59	23	)	)	PUNCT
bjp-70889	59	24	to	to	PART
bjp-70889	59	25	assess	assess	VERB
bjp-70889	59	26	the	the	DET
bjp-70889	59	27	impact	impact	NOUN
bjp-70889	59	28	of	of	ADP
bjp-70889	59	29	berberine	berberine	NOUN
bjp-70889	59	30	on	on	ADP
bjp-70889	59	31	key	key	ADJ
bjp-70889	59	32	markers	marker	NOUN
bjp-70889	59	33	of	of	ADP
bjp-70889	59	34	necroptosis	necroptosis	NOUN
bjp-70889	59	35	in	in	ADP
bjp-70889	59	36	h8	h8	PROPN
bjp-70889	59	37	cells	cell	NOUN
bjp-70889	59	38	,	,	PUNCT
bjp-70889	59	39	qrt	qrt	NOUN
bjp-70889	59	40	-	-	PUNCT
bjp-70889	59	41	pcr	pcr	NOUN
bjp-70889	59	42	was	be	AUX
bjp-70889	59	43	employed	employ	VERB
bjp-70889	59	44	to	to	PART
bjp-70889	59	45	analyze	analyze	VERB
bjp-70889	59	46	the	the	DET
bjp-70889	59	47	mrna	mrna	PROPN
bjp-70889	59	48	expression	expression	NOUN
bjp-70889	59	49	levels	level	NOUN
bjp-70889	59	50	.	.	PUNCT
bjp-70889	60	1	total	total	ADJ
bjp-70889	60	2	rna	rna	PROPN
bjp-70889	60	3	was	be	AUX
bjp-70889	60	4	extracted	extract	VERB
bjp-70889	60	5	from	from	ADP
bjp-70889	60	6	cells	cell	NOUN
bjp-70889	60	7	using	use	VERB
bjp-70889	60	8	molpure	molpure	NOUN
bjp-70889	60	9	cell	cell	NOUN
bjp-70889	60	10	/	/	SYM
bjp-70889	60	11	tissue	tissue	NOUN
bjp-70889	60	12	total	total	NOUN
bjp-70889	60	13	rna	rna	NOUN
bjp-70889	60	14	kit	kit	NOUN
bjp-70889	60	15	(	(	PUNCT
bjp-70889	60	16	yeasen	yeasen	PROPN
bjp-70889	60	17	,	,	PUNCT
bjp-70889	60	18	china	china	PROPN
bjp-70889	60	19	)	)	PUNCT
bjp-70889	60	20	,	,	PUNCT
bjp-70889	60	21	and	and	CCONJ
bjp-70889	60	22	reverse	reverse	ADJ
bjp-70889	60	23	transcription	transcription	NOUN
bjp-70889	60	24	was	be	AUX
bjp-70889	60	25	performed	perform	VERB
bjp-70889	60	26	with	with	ADP
bjp-70889	60	27	a	a	DET
bjp-70889	60	28	reverse	reverse	ADJ
bjp-70889	60	29	transcription	transcription	NOUN
bjp-70889	60	30	kit	kit	NOUN
bjp-70889	60	31	(	(	PUNCT
bjp-70889	60	32	cdna	cdna	PROPN
bjp-70889	60	33	with	with	ADP
bjp-70889	60	34	hiscript	hiscript	PROPN
bjp-70889	60	35	ii	ii	PROPN
bjp-70889	60	36	q	q	PROPN
bjp-70889	60	37	rt	rt	PROPN
bjp-70889	60	38	supermix	supermix	PROPN
bjp-70889	60	39	,	,	PUNCT
bjp-70889	60	40	vazyme	vazyme	NOUN
bjp-70889	60	41	,	,	PUNCT
bjp-70889	60	42	china	china	PROPN
bjp-70889	60	43	)	)	PUNCT
bjp-70889	60	44	.	.	PUNCT
bjp-70889	61	1	subsequently	subsequently	ADV
bjp-70889	61	2	,	,	PUNCT
bjp-70889	61	3	qrtpcr	qrtpcr	PROPN
bjp-70889	61	4	was	be	AUX
bjp-70889	61	5	performed	perform	VERB
bjp-70889	61	6	using	use	VERB
bjp-70889	61	7	sybr	sybr	ADP
bjp-70889	61	8	qpcr	qpcr	ADV
bjp-70889	61	9	master	master	NOUN
bjp-70889	61	10	mix	mix	NOUN
bjp-70889	61	11	(	(	PUNCT
bjp-70889	61	12	medicalbio	medicalbio	ADJ
bjp-70889	61	13	,	,	PUNCT
bjp-70889	61	14	mr0321	mr0321	PROPN
bjp-70889	61	15	)	)	PUNCT
bjp-70889	61	16	according	accord	VERB
bjp-70889	61	17	to	to	ADP
bjp-70889	61	18	instructions	instruction	NOUN
bjp-70889	61	19	.	.	PUNCT
bjp-70889	62	1	the	the	DET
bjp-70889	62	2	reaction	reaction	NOUN
bjp-70889	62	3	system	system	NOUN
bjp-70889	62	4	(	(	PUNCT
bjp-70889	62	5	20	20	NUM
bjp-70889	62	6	μl	μl	PRON
bjp-70889	62	7	)	)	PUNCT
bjp-70889	62	8	consisted	consist	VERB
bjp-70889	62	9	of	of	ADP
bjp-70889	62	10	1	1	NUM
bjp-70889	62	11	μl	μl	ADP
bjp-70889	62	12	cdna	cdna	PROPN
bjp-70889	62	13	template	template	NOUN
bjp-70889	62	14	,	,	PUNCT
bjp-70889	62	15	0.4	0.4	NUM
bjp-70889	62	16	μl	μl	ADP
bjp-70889	62	17	each	each	PRON
bjp-70889	62	18	of	of	ADP
bjp-70889	62	19	upstream	upstream	ADJ
bjp-70889	62	20	and	and	CCONJ
bjp-70889	62	21	downstream	downstream	ADJ
bjp-70889	62	22	primers	primer	NOUN
bjp-70889	62	23	,	,	PUNCT
bjp-70889	62	24	10	10	NUM
bjp-70889	62	25	μl	μl	DET
bjp-70889	62	26	sybr	sybr	PROPN
bjp-70889	62	27	premix	premix	PROPN
bjp-70889	62	28	ex	ex	X
bjp-70889	62	29	taq	taq	NOUN
bjp-70889	62	30	,	,	PUNCT
bjp-70889	62	31	and	and	CCONJ
bjp-70889	62	32	8.2	8.2	NUM
bjp-70889	62	33	μl	μl	NUM
bjp-70889	62	34	ddh2o	ddh2o	PROPN
bjp-70889	62	35	.	.	PUNCT
bjp-70889	63	1	β	β	X
bjp-70889	63	2	-	-	PUNCT
bjp-70889	63	3	actin	actin	NOUN
bjp-70889	63	4	served	serve	VERB
bjp-70889	63	5	as	as	ADP
bjp-70889	63	6	the	the	DET
bjp-70889	63	7	internal	internal	ADJ
bjp-70889	63	8	reference	reference	NOUN
bjp-70889	63	9	gene	gene	NOUN
bjp-70889	63	10	,	,	PUNCT
bjp-70889	63	11	and	and	CCONJ
bjp-70889	63	12	the	the	DET
bjp-70889	63	13	primer	primer	NOUN
bjp-70889	63	14	sequences	sequence	NOUN
bjp-70889	63	15	are	be	AUX
bjp-70889	63	16	detailed	detail	VERB
bjp-70889	63	17	in	in	ADP
bjp-70889	63	18	table	table	NOUN
bjp-70889	64	1	i	i	PRON
bjp-70889	64	2	(	(	PUNCT
bjp-70889	64	3	sangon	sangon	NOUN
bjp-70889	64	4	biotech	biotech	NOUN
bjp-70889	64	5	,	,	PUNCT
bjp-70889	64	6	china	china	PROPN
bjp-70889	64	7	)	)	PUNCT
bjp-70889	64	8	.	.	PUNCT
bjp-70889	65	1	the	the	DET
bjp-70889	65	2	relative	relative	ADJ
bjp-70889	65	3	mrna	mrna	PROPN
bjp-70889	65	4	expression	expression	NOUN
bjp-70889	65	5	was	be	AUX
bjp-70889	65	6	calculated	calculate	VERB
bjp-70889	65	7	by	by	ADP
bjp-70889	65	8	2	2	NUM
bjp-70889	65	9	△	△	NOUN
bjp-70889	65	10	△	△	X
bjp-70889	65	11	ct	ct	PROPN
bjp-70889	65	12	method	method	NOUN
bjp-70889	65	13	.	.	PUNCT
bjp-70889	66	1	immunofluorescence	immunofluorescence	NOUN
bjp-70889	66	2	assay	assay	VERB
bjp-70889	66	3	the	the	DET
bjp-70889	66	4	expression	expression	NOUN
bjp-70889	66	5	of	of	ADP
bjp-70889	66	6	ripk1	ripk1	NOUN
bjp-70889	66	7	in	in	ADP
bjp-70889	66	8	h8	h8	PROPN
bjp-70889	66	9	cells	cell	NOUN
bjp-70889	66	10	was	be	AUX
bjp-70889	66	11	examined	examine	VERB
bjp-70889	66	12	through	through	ADP
bjp-70889	66	13	immunofluorescence	immunofluorescence	NOUN
bjp-70889	66	14	assay	assay	NOUN
bjp-70889	66	15	under	under	ADP
bjp-70889	66	16	berberine	berberine	NOUN
bjp-70889	66	17	intervention	intervention	NOUN
bjp-70889	66	18	.	.	PUNCT
bjp-70889	67	1	cells	cell	NOUN
bjp-70889	67	2	were	be	AUX
bjp-70889	67	3	seeded	seed	VERB
bjp-70889	67	4	in	in	ADP
bjp-70889	67	5	24well	24well	NUM
bjp-70889	67	6	plates	plate	NOUN
bjp-70889	67	7	at	at	ADP
bjp-70889	67	8	a	a	DET
bjp-70889	67	9	density	density	NOUN
bjp-70889	67	10	of	of	ADP
bjp-70889	67	11	1×104	1×104	NUM
bjp-70889	67	12	cells	cell	NOUN
bjp-70889	67	13	/	/	SYM
bjp-70889	67	14	dish	dish	NOUN
bjp-70889	67	15	.	.	PUNCT
bjp-70889	68	1	after	after	ADP
bjp-70889	68	2	24	24	NUM
bjp-70889	68	3	hours	hour	NOUN
bjp-70889	68	4	of	of	ADP
bjp-70889	68	5	culture	culture	NOUN
bjp-70889	68	6	,	,	PUNCT
bjp-70889	68	7	the	the	DET
bjp-70889	68	8	culture	culture	NOUN
bjp-70889	68	9	medium	medium	NOUN
bjp-70889	68	10	was	be	AUX
bjp-70889	68	11	replaced	replace	VERB
bjp-70889	68	12	,	,	PUNCT
bjp-70889	68	13	and	and	CCONJ
bjp-70889	68	14	various	various	ADJ
bjp-70889	68	15	concentrations	concentration	NOUN
bjp-70889	68	16	of	of	ADP
bjp-70889	68	17	berberine	berberine	NOUN
bjp-70889	68	18	solution	solution	NOUN
bjp-70889	68	19	(	(	PUNCT
bjp-70889	68	20	0	0	NUM
bjp-70889	68	21	,	,	PUNCT
bjp-70889	68	22	20	20	NUM
bjp-70889	68	23	,	,	PUNCT
bjp-70889	68	24	40	40	NUM
bjp-70889	68	25	,	,	PUNCT
bjp-70889	68	26	80	80	NUM
bjp-70889	68	27	μm	μm	NUM
bjp-70889	68	28	/	/	SYM
bjp-70889	68	29	l	l	NOUN
bjp-70889	68	30	)	)	PUNCT
bjp-70889	68	31	were	be	AUX
bjp-70889	68	32	added	add	VERB
bjp-70889	68	33	for	for	ADP
bjp-70889	68	34	a	a	DET
bjp-70889	68	35	72hour	72hour	NUM
bjp-70889	68	36	incubation	incubation	NOUN
bjp-70889	68	37	period	period	NOUN
bjp-70889	68	38	.	.	PUNCT
bjp-70889	69	1	following	follow	VERB
bjp-70889	69	2	pbs	pbs	PROPN
bjp-70889	69	3	rinsing	rinsing	NOUN
bjp-70889	69	4	,	,	PUNCT
bjp-70889	69	5	cells	cell	NOUN
bjp-70889	69	6	were	be	AUX
bjp-70889	69	7	fixed	fix	VERB
bjp-70889	69	8	with	with	ADP
bjp-70889	69	9	4%paraformaldehyde	4%paraformaldehyde	NUM
bjp-70889	69	10	for	for	ADP
bjp-70889	69	11	10	10	NUM
bjp-70889	69	12	min	min	NOUN
bjp-70889	69	13	,	,	PUNCT
bjp-70889	69	14	and	and	CCONJ
bjp-70889	69	15	washed	wash	VERB
bjp-70889	69	16	thrice	thrice	NOUN
bjp-70889	69	17	with	with	ADP
bjp-70889	69	18	pbs	pbs	PROPN
bjp-70889	69	19	.	.	PUNCT
bjp-70889	70	1	antigen	antigen	PROPN
bjp-70889	70	2	retrieval	retrieval	NOUN
bjp-70889	70	3	was	be	AUX
bjp-70889	70	4	performed	perform	VERB
bjp-70889	70	5	at	at	ADP
bjp-70889	70	6	95	95	NUM
bjp-70889	70	7	℃	℃	PROPN
bjp-70889	70	8	with	with	ADP
bjp-70889	70	9	edta	edta	NOUN
bjp-70889	70	10	for	for	ADP
bjp-70889	70	11	10	10	NUM
bjp-70889	70	12	min	min	NOUN
bjp-70889	70	13	,	,	PUNCT
bjp-70889	70	14	followed	follow	VERB
bjp-70889	70	15	by	by	ADP
bjp-70889	70	16	three	three	NUM
bjp-70889	70	17	pbs	pbs	PROPN
bjp-70889	70	18	washes	wash	NOUN
bjp-70889	70	19	.	.	PUNCT
bjp-70889	71	1	subsequent	subsequent	ADJ
bjp-70889	71	2	ly	ly	NOUN
bjp-70889	71	3	,	,	PUNCT
bjp-70889	71	4	cells	cell	NOUN
bjp-70889	71	5	were	be	AUX
bjp-70889	71	6	treated	treat	VERB
bjp-70889	71	7	with	with	ADP
bjp-70889	71	8	0.2%triton	0.2%triton	NUM
bjp-70889	71	9	x-100	x-100	PROPN
bjp-70889	72	1	for	for	ADP
bjp-70889	72	2	10	10	NUM
bjp-70889	72	3	min	min	NOUN
bjp-70889	73	1	and	and	CCONJ
bjp-70889	73	2	washed	wash	VERB
bjp-70889	73	3	thrice	thrice	NOUN
bjp-70889	73	4	with	with	ADP
bjp-70889	73	5	pbs	pbs	PROPN
bjp-70889	73	6	.	.	PUNCT
bjp-70889	74	1	blocking	blocking	NOUN
bjp-70889	74	2	was	be	AUX
bjp-70889	74	3	carried	carry	VERB
bjp-70889	74	4	out	out	ADP
bjp-70889	74	5	with	with	ADP
bjp-70889	74	6	pbst	pbst	ADJ
bjp-70889	74	7	containing	contain	VERB
bjp-70889	74	8	3	3	NUM
bjp-70889	74	9	%	%	NOUN
bjp-70889	74	10	bsa	bsa	PROPN
bjp-70889	74	11	(	(	PUNCT
bjp-70889	74	12	pbs	pbs	PROPN
bjp-70889	74	13	+	+	X
bjp-70889	74	14	0.1%tween	0.1%tween	NUM
bjp-70889	74	15	20	20	NUM
bjp-70889	74	16	)	)	PUNCT
bjp-70889	74	17	at	at	ADP
bjp-70889	74	18	room	room	NOUN
bjp-70889	74	19	temperature	temperature	NOUN
bjp-70889	74	20	for	for	ADP
bjp-70889	74	21	30	30	NUM
bjp-70889	74	22	min	min	NOUN
bjp-70889	74	23	.	.	PROPN
bjp-70889	74	24	primary	primary	ADJ
bjp-70889	74	25	antibodies	antibody	NOUN
bjp-70889	74	26	(	(	PUNCT
bjp-70889	74	27	ripk1	ripk1	NOUN
bjp-70889	74	28	/	/	SYM
bjp-70889	74	29	rip	rip	ADJ
bjp-70889	74	30	rabbit	rabbit	NOUN
bjp-70889	74	31	pab	pab	NOUN
bjp-70889	74	32	,	,	PUNCT
bjp-70889	74	33	box	box	NOUN
bjp-70889	74	34	1	1	NUM
bjp-70889	74	35	:	:	PUNCT
bjp-70889	74	36	western	western	ADJ
bjp-70889	74	37	blot	blot	NOUN
bjp-70889	74	38	analysis	analysis	NOUN
bjp-70889	74	39	principle	principle	ADJ
bjp-70889	74	40	western	western	ADJ
bjp-70889	74	41	blotting	blotting	NOUN
bjp-70889	74	42	is	be	AUX
bjp-70889	74	43	based	base	VERB
bjp-70889	74	44	on	on	ADP
bjp-70889	74	45	the	the	DET
bjp-70889	74	46	principle	principle	NOUN
bjp-70889	74	47	of	of	ADP
bjp-70889	74	48	immunochromatography	immunochromatography	NOUN
bjp-70889	74	49	where	where	SCONJ
bjp-70889	74	50	proteins	protein	NOUN
bjp-70889	74	51	are	be	AUX
bjp-70889	74	52	separated	separate	VERB
bjp-70889	74	53	into	into	ADP
bjp-70889	74	54	polyacrylamide	polyacrylamide	ADJ
bjp-70889	74	55	gel	gel	NOUN
bjp-70889	74	56	according	accord	VERB
bjp-70889	74	57	to	to	ADP
bjp-70889	74	58	their	their	PRON
bjp-70889	74	59	molecular	molecular	ADJ
bjp-70889	74	60	weight	weight	NOUN
bjp-70889	74	61	.	.	PUNCT
bjp-70889	75	1	requirements	requirement	NOUN
bjp-70889	75	2	bca	bca	PROPN
bjp-70889	75	3	protein	protein	NOUN
bjp-70889	75	4	assay	assay	NOUN
bjp-70889	75	5	kit	kit	NOUN
bjp-70889	75	6	(	(	PUNCT
bjp-70889	75	7	beyotime	beyotime	NOUN
bjp-70889	75	8	,	,	PUNCT
bjp-70889	75	9	china	china	PROPN
bjp-70889	75	10	,	,	PUNCT
bjp-70889	75	11	p0009	p0009	PROPN
bjp-70889	75	12	)	)	PUNCT
bjp-70889	75	13	,	,	PUNCT
bjp-70889	75	14	cells	cell	NOUN
bjp-70889	75	15	pellet	pellet	NOUN
bjp-70889	75	16	,	,	PUNCT
bjp-70889	75	17	ecl	ecl	PROPN
bjp-70889	75	18	(	(	PUNCT
bjp-70889	75	19	medicalbio	medicalbio	ADJ
bjp-70889	75	20	,	,	PUNCT
bjp-70889	75	21	pt01001	pt01001	NOUN
bjp-70889	75	22	)	)	PUNCT
bjp-70889	75	23	luminescence	luminescence	NOUN
bjp-70889	75	24	,	,	PUNCT
bjp-70889	75	25	ripa	ripa	NOUN
bjp-70889	75	26	buffer	buffer	NOUN
bjp-70889	75	27	,	,	PUNCT
bjp-70889	75	28	protease	protease	NOUN
bjp-70889	75	29	cocktail	cocktail	NOUN
bjp-70889	75	30	,	,	PUNCT
bjp-70889	75	31	blocking	block	VERB
bjp-70889	75	32	buffer	buffer	NOUN
bjp-70889	75	33	,	,	PUNCT
bjp-70889	75	34	primary	primary	ADJ
bjp-70889	75	35	antibodies	antibody	NOUN
bjp-70889	75	36	,	,	PUNCT
bjp-70889	75	37	secondary	secondary	ADJ
bjp-70889	75	38	antibodies	antibody	NOUN
bjp-70889	75	39	,	,	PUNCT
bjp-70889	75	40	phosphate	phosphate	ADJ
bjp-70889	75	41	saline	saline	NOUN
bjp-70889	75	42	buffer	buffer	NOUN
bjp-70889	75	43	,	,	PUNCT
bjp-70889	75	44	1xtris	1xtris	NUM
bjp-70889	75	45	-	-	PUNCT
bjp-70889	75	46	buffered	buffer	VERB
bjp-70889	75	47	saline	saline	NOUN
bjp-70889	75	48	,	,	PUNCT
bjp-70889	75	49	0.1%tween	0.1%tween	NUM
bjp-70889	75	50	,	,	PUNCT
bjp-70889	75	51	sodium	sodium	NOUN
bjp-70889	75	52	polyacrylamide	polyacrylamide	NOUN
bjp-70889	75	53	gel	gel	PROPN
bjp-70889	75	54	,	,	PUNCT
bjp-70889	75	55	pvdf	pvdf	PROPN
bjp-70889	75	56	membranes	membrane	NOUN
bjp-70889	75	57	,	,	PUNCT
bjp-70889	75	58	transfer	transfer	NOUN
bjp-70889	75	59	buffer	buffer	NOUN
bjp-70889	75	60	procedure	procedure	NOUN
bjp-70889	75	61	step	step	NOUN
bjp-70889	75	62	1	1	NUM
bjp-70889	75	63	:	:	PUNCT
bjp-70889	75	64	cells	cell	NOUN
bjp-70889	75	65	were	be	AUX
bjp-70889	75	66	seeded	seed	VERB
bjp-70889	75	67	in	in	ADP
bjp-70889	75	68	6	6	NUM
bjp-70889	75	69	-	-	PUNCT
bjp-70889	75	70	well	well	NOUN
bjp-70889	75	71	plates	plate	NOUN
bjp-70889	75	72	at	at	ADP
bjp-70889	75	73	a	a	DET
bjp-70889	75	74	density	density	NOUN
bjp-70889	75	75	of	of	ADP
bjp-70889	75	76	2×105	2×105	NUM
bjp-70889	75	77	cells	cell	NOUN
bjp-70889	75	78	/	/	SYM
bjp-70889	75	79	dish	dish	NOUN
bjp-70889	75	80	.	.	PUNCT
bjp-70889	76	1	step	step	NOUN
bjp-70889	76	2	2	2	NUM
bjp-70889	76	3	:	:	PUNCT
bjp-70889	76	4	after	after	ADP
bjp-70889	76	5	24	24	NUM
bjp-70889	76	6	hours	hour	NOUN
bjp-70889	76	7	of	of	ADP
bjp-70889	76	8	incubation	incubation	NOUN
bjp-70889	76	9	,	,	PUNCT
bjp-70889	76	10	the	the	DET
bjp-70889	76	11	culture	culture	NOUN
bjp-70889	76	12	medium	medium	NOUN
bjp-70889	76	13	was	be	AUX
bjp-70889	76	14	discarded	discard	VERB
bjp-70889	76	15	,	,	PUNCT
bjp-70889	76	16	and	and	CCONJ
bjp-70889	76	17	berberine	berberine	NOUN
bjp-70889	76	18	solutions	solution	NOUN
bjp-70889	76	19	at	at	ADP
bjp-70889	76	20	different	different	ADJ
bjp-70889	76	21	concentrations	concentration	NOUN
bjp-70889	76	22	(	(	PUNCT
bjp-70889	76	23	0	0	NUM
bjp-70889	76	24	,	,	PUNCT
bjp-70889	76	25	20	20	NUM
bjp-70889	76	26	,	,	PUNCT
bjp-70889	76	27	40	40	NUM
bjp-70889	76	28	,	,	PUNCT
bjp-70889	76	29	80	80	NUM
bjp-70889	76	30	μm	μm	NUM
bjp-70889	76	31	/	/	SYM
bjp-70889	76	32	l	l	NOUN
bjp-70889	76	33	)	)	PUNCT
bjp-70889	76	34	were	be	AUX
bjp-70889	76	35	added	add	VERB
bjp-70889	76	36	for	for	ADP
bjp-70889	76	37	a	a	DET
bjp-70889	76	38	72	72	NUM
bjp-70889	76	39	-	-	PUNCT
bjp-70889	76	40	hour	hour	NOUN
bjp-70889	76	41	incubation	incubation	NOUN
bjp-70889	76	42	period	period	NOUN
bjp-70889	76	43	.	.	PUNCT
bjp-70889	77	1	step	step	NOUN
bjp-70889	77	2	3	3	NUM
bjp-70889	77	3	:	:	PUNCT
bjp-70889	77	4	subsequently	subsequently	ADV
bjp-70889	77	5	,	,	PUNCT
bjp-70889	77	6	cells	cell	NOUN
bjp-70889	77	7	were	be	AUX
bjp-70889	77	8	washed	wash	VERB
bjp-70889	77	9	twice	twice	ADV
bjp-70889	77	10	with	with	ADP
bjp-70889	77	11	pbs	pbs	PROPN
bjp-70889	77	12	and	and	CCONJ
bjp-70889	77	13	lysed	lyse	VERB
bjp-70889	77	14	using	use	VERB
bjp-70889	77	15	ice	ice	NOUN
bjp-70889	77	16	-	-	PUNCT
bjp-70889	77	17	cold	cold	ADJ
bjp-70889	77	18	ripa	ripa	NOUN
bjp-70889	77	19	lysate	lysate	NOUN
bjp-70889	77	20	containing	contain	VERB
bjp-70889	77	21	pmsf	pmsf	NOUN
bjp-70889	77	22	(	(	PUNCT
bjp-70889	77	23	100x	100x	NUM
bjp-70889	77	24	)	)	PUNCT
bjp-70889	77	25	,	,	PUNCT
bjp-70889	77	26	phosphatase	phosphatase	NOUN
bjp-70889	77	27	inhibitor	inhibitor	NOUN
bjp-70889	77	28	(	(	PUNCT
bjp-70889	77	29	50x	50x	NUM
bjp-70889	77	30	)	)	PUNCT
bjp-70889	77	31	,	,	PUNCT
bjp-70889	77	32	and	and	CCONJ
bjp-70889	77	33	protease	protease	NOUN
bjp-70889	77	34	inhibitor	inhibitor	NOUN
bjp-70889	77	35	(	(	PUNCT
bjp-70889	77	36	50x	50x	NUM
bjp-70889	77	37	)	)	PUNCT
bjp-70889	77	38	to	to	PART
bjp-70889	77	39	extract	extract	VERB
bjp-70889	77	40	proteins	protein	NOUN
bjp-70889	77	41	.	.	PUNCT
bjp-70889	78	1	step	step	NOUN
bjp-70889	78	2	4	4	NUM
bjp-70889	78	3	:	:	PUNCT
bjp-70889	78	4	protein	protein	NOUN
bjp-70889	78	5	concentration	concentration	NOUN
bjp-70889	78	6	obtained	obtain	VERB
bjp-70889	78	7	from	from	ADP
bjp-70889	78	8	cell	cell	NOUN
bjp-70889	78	9	lysis	lysis	NOUN
bjp-70889	78	10	was	be	AUX
bjp-70889	78	11	then	then	ADV
bjp-70889	78	12	quantified	quantify	VERB
bjp-70889	78	13	with	with	ADP
bjp-70889	78	14	bca	bca	PROPN
bjp-70889	78	15	protein	protein	NOUN
bjp-70889	78	16	assay	assay	NOUN
bjp-70889	78	17	kit	kit	NOUN
bjp-70889	78	18	step	step	NOUN
bjp-70889	78	19	5	5	NUM
bjp-70889	78	20	:	:	PUNCT
bjp-70889	78	21	proteins	protein	NOUN
bjp-70889	78	22	were	be	AUX
bjp-70889	78	23	separated	separate	VERB
bjp-70889	78	24	on	on	ADP
bjp-70889	78	25	sds	sds	PROPN
bjp-70889	78	26	-	-	PUNCT
bjp-70889	78	27	polyacrylamide	polyacrylamide	NOUN
bjp-70889	78	28	gels	gel	NOUN
bjp-70889	78	29	via	via	ADP
bjp-70889	78	30	electrophoresis	electrophoresis	NOUN
bjp-70889	78	31	and	and	CCONJ
bjp-70889	78	32	then	then	ADV
bjp-70889	78	33	transferred	transfer	VERB
bjp-70889	78	34	to	to	ADP
bjp-70889	78	35	pvdf	pvdf	PROPN
bjp-70889	78	36	membranes	membrane	NOUN
bjp-70889	78	37	.	.	PUNCT
bjp-70889	79	1	step	step	NOUN
bjp-70889	79	2	6	6	NUM
bjp-70889	79	3	:	:	PUNCT
bjp-70889	79	4	membranes	membrane	NOUN
bjp-70889	79	5	were	be	AUX
bjp-70889	79	6	blocked	block	VERB
bjp-70889	79	7	with	with	ADP
bjp-70889	79	8	5	5	NUM
bjp-70889	79	9	%	%	NOUN
bjp-70889	79	10	non	non	ADJ
bjp-70889	79	11	-	-	ADJ
bjp-70889	79	12	fat	fat	ADJ
bjp-70889	79	13	dry	dry	ADJ
bjp-70889	79	14	milk	milk	NOUN
bjp-70889	79	15	(	(	PUNCT
bjp-70889	79	16	or	or	CCONJ
bjp-70889	79	17	bsa	bsa	NOUN
bjp-70889	79	18	)	)	PUNCT
bjp-70889	79	19	solution	solution	NOUN
bjp-70889	79	20	in	in	ADP
bjp-70889	79	21	tbst	tbst	PROPN
bjp-70889	79	22	(	(	PUNCT
bjp-70889	79	23	tbs	tbs	NOUN
bjp-70889	79	24	+	+	X
bjp-70889	79	25	0.1%tween	0.1%tween	NUM
bjp-70889	79	26	20	20	NUM
bjp-70889	79	27	)	)	PUNCT
bjp-70889	79	28	for	for	ADP
bjp-70889	79	29	1	1	NUM
bjp-70889	79	30	hour	hour	NOUN
bjp-70889	79	31	at	at	ADP
bjp-70889	79	32	room	room	NOUN
bjp-70889	79	33	temperature	temperature	NOUN
bjp-70889	79	34	.	.	PUNCT
bjp-70889	80	1	step	step	NOUN
bjp-70889	80	2	7	7	NUM
bjp-70889	80	3	:	:	PUNCT
bjp-70889	80	4	this	this	PRON
bjp-70889	80	5	was	be	AUX
bjp-70889	80	6	followed	follow	VERB
bjp-70889	80	7	by	by	ADP
bjp-70889	80	8	overnight	overnight	ADJ
bjp-70889	80	9	incubation	incubation	NOUN
bjp-70889	80	10	at	at	ADP
bjp-70889	80	11	4	4	NUM
bjp-70889	80	12	°	°	NUM
bjp-70889	80	13	c	c	NOUN
bjp-70889	80	14	with	with	ADP
bjp-70889	80	15	the	the	DET
bjp-70889	80	16	primary	primary	ADJ
bjp-70889	80	17	antibody	antibody	NOUN
bjp-70889	80	18	:	:	PUNCT
bjp-70889	80	19	ripk1	ripk1	ADJ
bjp-70889	80	20	-	-	PUNCT
bjp-70889	80	21	specific	specific	ADJ
bjp-70889	80	22	polyclonal	polyclonal	ADJ
bjp-70889	80	23	antibody	antibody	NOUN
bjp-70889	80	24	(	(	PUNCT
bjp-70889	80	25	proteintech	proteintech	NOUN
bjp-70889	80	26	,	,	PUNCT
bjp-70889	80	27	17519	17519	NUM
bjp-70889	80	28	-	-	SYM
bjp-70889	80	29	1	1	NUM
bjp-70889	80	30	-	-	PUNCT
bjp-70889	80	31	ap，1:1500	ap，1:1500	NOUN
bjp-70889	80	32	)	)	PUNCT
bjp-70889	80	33	,	,	PUNCT
bjp-70889	80	34	mlkl	mlkl	VERB
bjp-70889	80	35	rabbit	rabbit	NOUN
bjp-70889	80	36	mab	mab	NOUN
bjp-70889	80	37	(	(	PUNCT
bjp-70889	80	38	zenbio	zenbio	ADV
bjp-70889	80	39	,	,	PUNCT
bjp-70889	80	40	r380559	r380559	PROPN
bjp-70889	80	41	,	,	PUNCT
bjp-70889	80	42	1:1000	1:1000	NUM
bjp-70889	80	43	)	)	PUNCT
bjp-70889	80	44	,	,	PUNCT
bjp-70889	80	45	phospho	phospho	NOUN
bjp-70889	80	46	-	-	PUNCT
bjp-70889	80	47	mlkl	mlkl	NOUN
bjp-70889	80	48	(	(	PUNCT
bjp-70889	80	49	ser358	ser358	NOUN
bjp-70889	80	50	)	)	PUNCT
bjp-70889	80	51	rabbit	rabbit	NOUN
bjp-70889	80	52	mab	mab	NOUN
bjp-70889	80	53	(	(	PUNCT
bjp-70889	80	54	zenbio	zenbio	ADV
bjp-70889	80	55	,	,	PUNCT
bjp-70889	80	56	a7414	a7414	PROPN
bjp-70889	80	57	,	,	PUNCT
bjp-70889	80	58	1:1000	1:1000	NUM
bjp-70889	80	59	)	)	PUNCT
bjp-70889	80	60	,	,	PUNCT
bjp-70889	80	61	cleaved	cleaved	ADJ
bjp-70889	80	62	caspase	caspase	NOUN
bjp-70889	80	63	8	8	NUM
bjp-70889	80	64	mouse	mouse	NOUN
bjp-70889	80	65	mab	mab	NOUN
bjp-70889	80	66	(	(	PUNCT
bjp-70889	80	67	zenbio	zenbio	ADV
bjp-70889	80	68	,	,	PUNCT
bjp-70889	80	69	250106	250106	NUM
bjp-70889	80	70	,	,	PUNCT
bjp-70889	80	71	1:1000	1:1000	NUM
bjp-70889	80	72	)	)	PUNCT
bjp-70889	80	73	,	,	PUNCT
bjp-70889	80	74	cleaved	cleaved	ADJ
bjp-70889	80	75	caspase	caspase	NOUN
bjp-70889	80	76	3	3	NUM
bjp-70889	80	77	rabbit	rabbit	NOUN
bjp-70889	80	78	mab	mab	NOUN
bjp-70889	80	79	(	(	PUNCT
bjp-70889	80	80	zenbio	zenbio	ADV
bjp-70889	80	81	,	,	PUNCT
bjp-70889	80	82	341034，1:1000	341034，1:1000	NUM
bjp-70889	80	83	)	)	PUNCT
bjp-70889	80	84	,	,	PUNCT
bjp-70889	80	85	βactin	βactin	NOUN
bjp-70889	80	86	antibody	antibody	NOUN
bjp-70889	80	87	(	(	PUNCT
bjp-70889	80	88	proteintech	proteintech	NOUN
bjp-70889	80	89	,	,	PUNCT
bjp-70889	80	90	81115	81115	NUM
bjp-70889	80	91	-	-	SYM
bjp-70889	80	92	1	1	NUM
bjp-70889	80	93	-	-	PUNCT
bjp-70889	80	94	rr	rr	NOUN
bjp-70889	80	95	,	,	PUNCT
bjp-70889	80	96	1:10000	1:10000	NUM
bjp-70889	80	97	)	)	PUNCT
bjp-70889	80	98	diluted	dilute	VERB
bjp-70889	80	99	in	in	ADP
bjp-70889	80	100	the	the	DET
bjp-70889	80	101	blocking	blocking	NOUN
bjp-70889	80	102	solution	solution	NOUN
bjp-70889	80	103	.	.	PUNCT
bjp-70889	81	1	step	step	NOUN
bjp-70889	81	2	8	8	NUM
bjp-70889	81	3	:	:	PUNCT
bjp-70889	81	4	after	after	ADP
bjp-70889	81	5	three	three	NUM
bjp-70889	81	6	washes	wash	NOUN
bjp-70889	81	7	with	with	ADP
bjp-70889	81	8	tbst	tbst	ADJ
bjp-70889	81	9	buffer	buffer	NOUN
bjp-70889	81	10	,	,	PUNCT
bjp-70889	81	11	membranes	membrane	NOUN
bjp-70889	81	12	were	be	AUX
bjp-70889	81	13	incubated	incubate	VERB
bjp-70889	81	14	with	with	ADP
bjp-70889	81	15	hrp	hrp	PROPN
bjp-70889	81	16	-	-	PUNCT
bjp-70889	81	17	conjugated	conjugate	VERB
bjp-70889	81	18	secondary	secondary	ADJ
bjp-70889	81	19	antibodies	antibody	NOUN
bjp-70889	82	1	[	[	X
bjp-70889	82	2	goat	goat	PROPN
bjp-70889	82	3	anti	anti	ADJ
bjp-70889	82	4	-	-	ADJ
bjp-70889	82	5	rabbit	rabbit	ADJ
bjp-70889	82	6	igg	igg	PROPN
bjp-70889	82	7	(	(	PUNCT
bjp-70889	82	8	abclonal	abclonal	ADJ
bjp-70889	82	9	,	,	PUNCT
bjp-70889	82	10	as014	as014	ADV
bjp-70889	82	11	,	,	PUNCT
bjp-70889	82	12	1:7500	1:7500	NUM
bjp-70889	82	13	)	)	PUNCT
bjp-70889	82	14	or	or	CCONJ
bjp-70889	82	15	hrp	hrp	PROPN
bjp-70889	82	16	-	-	PUNCT
bjp-70889	82	17	conjugated	conjugate	VERB
bjp-70889	82	18	sffinipure	sffinipure	PROPN
bjp-70889	82	19	goat	goat	PROPN
bjp-70889	82	20	anti	anti	PROPN
bjp-70889	82	21	mouse	mouse	PROPN
bjp-70889	82	22	igg(h+l)(proteintech	igg(h+l)(proteintech	NOUN
bjp-70889	82	23	,	,	PUNCT
bjp-70889	82	24	sa00001	sa00001	NOUN
bjp-70889	82	25	-	-	PUNCT
bjp-70889	82	26	1	1	NUM
bjp-70889	82	27	,	,	PUNCT
bjp-70889	82	28	1:7500	1:7500	NUM
bjp-70889	82	29	)	)	PUNCT
bjp-70889	82	30	]	]	PUNCT
bjp-70889	82	31	for	for	ADP
bjp-70889	82	32	1	1	NUM
bjp-70889	82	33	hour	hour	NOUN
bjp-70889	82	34	at	at	ADP
bjp-70889	82	35	room	room	NOUN
bjp-70889	82	36	temperature	temperature	NOUN
bjp-70889	82	37	.	.	PUNCT
bjp-70889	83	1	step	step	NOUN
bjp-70889	83	2	9	9	NUM
bjp-70889	83	3	:	:	PUNCT
bjp-70889	83	4	subsequent	subsequent	ADJ
bjp-70889	83	5	washes	wash	NOUN
bjp-70889	83	6	with	with	ADP
bjp-70889	83	7	tbst	tbst	ADJ
bjp-70889	83	8	washing	washing	NOUN
bjp-70889	83	9	buffer	buffer	NOUN
bjp-70889	83	10	were	be	AUX
bjp-70889	83	11	followed	follow	VERB
bjp-70889	83	12	by	by	ADP
bjp-70889	83	13	development	development	NOUN
bjp-70889	83	14	with	with	ADP
bjp-70889	83	15	ecl	ecl	PROPN
bjp-70889	83	16	(	(	PUNCT
bjp-70889	83	17	medicalbio	medicalbio	ADJ
bjp-70889	83	18	,	,	PUNCT
bjp-70889	83	19	pt01001	pt01001	NOUN
bjp-70889	83	20	)	)	PUNCT
bjp-70889	83	21	luminescence	luminescence	NOUN
bjp-70889	83	22	.	.	PUNCT
bjp-70889	84	1	step	step	NOUN
bjp-70889	84	2	10	10	NUM
bjp-70889	84	3	:	:	PUNCT
bjp-70889	84	4	using	use	VERB
bjp-70889	84	5	β	β	NOUN
bjp-70889	84	6	-	-	NOUN
bjp-70889	84	7	actin	actin	NOUN
bjp-70889	84	8	as	as	ADP
bjp-70889	84	9	internal	internal	ADJ
bjp-70889	84	10	reference	reference	NOUN
bjp-70889	84	11	protein	protein	NOUN
bjp-70889	84	12	,	,	PUNCT
bjp-70889	84	13	band	band	NOUN
bjp-70889	84	14	analysis	analysis	NOUN
bjp-70889	84	15	was	be	AUX
bjp-70889	84	16	performed	perform	VERB
bjp-70889	84	17	by	by	ADP
bjp-70889	84	18	imagej	imagej	ADJ
bjp-70889	84	19	software	software	NOUN
bjp-70889	84	20	.	.	PUNCT
bjp-70889	85	1	reference	reference	NOUN
bjp-70889	85	2	chen	chen	PROPN
bjp-70889	85	3	et	et	PROPN
bjp-70889	85	4	al	al	PROPN
bjp-70889	85	5	.	.	PROPN
bjp-70889	85	6	,	,	PUNCT
bjp-70889	85	7	2019	2019	NUM
bjp-70889	85	8	references	reference	NOUN
bjp-70889	85	9	(	(	PUNCT
bjp-70889	85	10	video	video	NOUN
bjp-70889	85	11	)	)	PUNCT
bjp-70889	85	12	lim	lim	PROPN
bjp-70889	85	13	et	et	PROPN
bjp-70889	85	14	al	al	PROPN
bjp-70889	85	15	.	.	PROPN
bjp-70889	85	16	,	,	PUNCT
bjp-70889	85	17	2022	2022	NUM
bjp-70889	85	18	;	;	PUNCT
bjp-70889	85	19	song	song	NOUN
bjp-70889	85	20	et	et	PROPN
bjp-70889	85	21	al	al	PROPN
bjp-70889	85	22	.	.	PROPN
bjp-70889	85	23	,	,	PUNCT
bjp-70889	85	24	2021	2021	NUM
bjp-70889	85	25	table	table	NOUN
bjp-70889	85	26	i	i	PRON
bjp-70889	85	27	primer	primer	NOUN
bjp-70889	85	28	design	design	NOUN
bjp-70889	85	29	primer	primer	NOUN
bjp-70889	85	30	name	name	NOUN
bjp-70889	85	31	primer	primer	NOUN
bjp-70889	85	32	sequence（5	sequence（5	NOUN
bjp-70889	85	33	'	'	PUNCT
bjp-70889	85	34	to	to	ADP
bjp-70889	85	35	3	3	NUM
bjp-70889	85	36	'	'	NOUN
bjp-70889	85	37	）	）	PUNCT
bjp-70889	85	38	ripk1	ripk1	PROPN
bjp-70889	85	39	-	-	PUNCT
bjp-70889	85	40	f	f	PROPN
bjp-70889	85	41	tggttcttcagtacctctaccag	tggttcttcagtacctctaccag	VERB
bjp-70889	85	42	ripk1	ripk1	PROPN
bjp-70889	85	43	-	-	PUNCT
bjp-70889	85	44	r	r	NOUN
bjp-70889	85	45	gcctgtggtttgagcattgatt	gcctgtggtttgagcattgatt	NOUN
bjp-70889	85	46	mlkl	mlkl	PROPN
bjp-70889	85	47	-	-	PUNCT
bjp-70889	85	48	f	f	NOUN
bjp-70889	85	49	aggaggctaatggggagataga	aggaggctaatggggagataga	NOUN
bjp-70889	85	50	mlkl	mlkl	NOUN
bjp-70889	85	51	-	-	PUNCT
bjp-70889	85	52	r	r	NOUN
bjp-70889	85	53	tggcttgctgttagaaacctg	tggcttgctgttagaaacctg	NOUN
bjp-70889	85	54	β	β	X
bjp-70889	85	55	-	-	PUNCT
bjp-70889	85	56	actin	actin	NOUN
bjp-70889	85	57	-	-	PUNCT
bjp-70889	85	58	f	f	PROPN
bjp-70889	85	59	cctggcacccagcacaat	cctggcacccagcacaat	PROPN
bjp-70889	85	60	β	β	X
bjp-70889	85	61	-	-	PUNCT
bjp-70889	85	62	actin	actin	NOUN
bjp-70889	85	63	-	-	PUNCT
bjp-70889	85	64	r	r	NOUN
bjp-70889	85	65	gggccggactcgtcatac	gggccggactcgtcatac	NOUN
bjp-70889	85	66	bangladesh	bangladesh	PROPN
bjp-70889	85	67	j	j	PROPN
bjp-70889	85	68	pharmacol	pharmacol	PROPN
bjp-70889	85	69	2024	2024	NUM
bjp-70889	85	70	;	;	PUNCT
bjp-70889	85	71	19	19	NUM
bjp-70889	85	72	:	:	SYM
bjp-70889	85	73	13	13	NUM
bjp-70889	85	74	-	-	SYM
bjp-70889	85	75	22	22	NUM
bjp-70889	85	76	15	15	NUM
bjp-70889	85	77	abclonal	abclonal	ADJ
bjp-70889	85	78	,	,	PUNCT
bjp-70889	85	79	a7414	a7414	PROPN
bjp-70889	85	80	,	,	PUNCT
bjp-70889	85	81	1:200	1:200	NUM
bjp-70889	85	82	)	)	PUNCT
bjp-70889	85	83	were	be	AUX
bjp-70889	85	84	incubated	incubate	VERB
bjp-70889	85	85	with	with	ADP
bjp-70889	85	86	pbst	pbst	ADV
bjp-70889	85	87	containing	contain	VERB
bjp-70889	85	88	3%bsa	3%bsa	NOUN
bjp-70889	85	89	overnight	overnight	ADV
bjp-70889	85	90	at	at	ADP
bjp-70889	85	91	4	4	NUM
bjp-70889	85	92	℃	℃	PROPN
bjp-70889	85	93	,	,	PUNCT
bjp-70889	85	94	followed	follow	VERB
bjp-70889	85	95	by	by	ADP
bjp-70889	85	96	three	three	NUM
bjp-70889	85	97	washes	wash	NOUN
bjp-70889	85	98	with	with	ADP
bjp-70889	85	99	pbs	pbs	PROPN
bjp-70889	85	100	.	.	PUNCT
bjp-70889	86	1	cells	cell	NOUN
bjp-70889	86	2	were	be	AUX
bjp-70889	86	3	then	then	ADV
bjp-70889	86	4	incubated	incubate	VERB
bjp-70889	86	5	in	in	ADP
bjp-70889	86	6	3%bsa	3%bsa	NUM
bjp-70889	86	7	in	in	ADP
bjp-70889	86	8	pbst	pbst	ADV
bjp-70889	86	9	for	for	ADP
bjp-70889	86	10	1	1	NUM
bjp-70889	86	11	hour	hour	NOUN
bjp-70889	86	12	in	in	ADP
bjp-70889	86	13	the	the	DET
bjp-70889	86	14	dark	dark	NOUN
bjp-70889	86	15	with	with	ADP
bjp-70889	86	16	the	the	DET
bjp-70889	86	17	respective	respective	ADJ
bjp-70889	86	18	fluorescent	fluorescent	NOUN
bjp-70889	86	19	-	-	PUNCT
bjp-70889	86	20	conjugated	conjugate	VERB
bjp-70889	86	21	secondary	secondary	ADJ
bjp-70889	86	22	antibody	antibody	NOUN
bjp-70889	86	23	(	(	PUNCT
bjp-70889	86	24	coralite488	coralite488	PROPN
bjp-70889	86	25	-	-	PUNCT
bjp-70889	86	26	conjugated	conjugate	VERB
bjp-70889	86	27	goat	goat	PROPN
bjp-70889	86	28	anti	anti	ADJ
bjp-70889	86	29	-	-	ADJ
bjp-70889	86	30	rabbit	rabbit	ADJ
bjp-70889	86	31	igg	igg	PROPN
bjp-70889	86	32	(	(	PUNCT
bjp-70889	86	33	h+l	h+l	PROPN
bjp-70889	86	34	)	)	PUNCT
bjp-70889	86	35	,	,	PUNCT
bjp-70889	86	36	proteintech	proteintech	NOUN
bjp-70889	86	37	,	,	PUNCT
bjp-70889	86	38	sa000132,1:500	sa000132,1:500	NOUN
bjp-70889	86	39	)	)	PUNCT
bjp-70889	86	40	followed	follow	VERB
bjp-70889	86	41	by	by	ADP
bjp-70889	86	42	washing	wash	VERB
bjp-70889	86	43	with	with	ADP
bjp-70889	86	44	pbst	pbst	PROPN
bjp-70889	86	45	.	.	PUNCT
bjp-70889	87	1	dapi	dapi	PROPN
bjp-70889	87	2	was	be	AUX
bjp-70889	87	3	applied	apply	VERB
bjp-70889	87	4	to	to	ADP
bjp-70889	87	5	the	the	DET
bjp-70889	87	6	nuclei	nucleus	NOUN
bjp-70889	87	7	for	for	ADP
bjp-70889	87	8	5	5	NUM
bjp-70889	87	9	min	min	NOUN
bjp-70889	87	10	,	,	PUNCT
bjp-70889	87	11	washed	wash	VERB
bjp-70889	87	12	with	with	ADP
bjp-70889	87	13	pbs	pbs	PROPN
bjp-70889	87	14	,	,	PUNCT
bjp-70889	87	15	and	and	CCONJ
bjp-70889	87	16	observed	observe	VERB
bjp-70889	87	17	by	by	ADP
bjp-70889	87	18	fluorescence	fluorescence	NOUN
bjp-70889	87	19	microscopy	microscopy	NOUN
bjp-70889	87	20	.	.	PUNCT
bjp-70889	88	1	the	the	DET
bjp-70889	88	2	fluorescence	fluorescence	NOUN
bjp-70889	88	3	intensity	intensity	NOUN
bjp-70889	88	4	was	be	AUX
bjp-70889	88	5	analyzed	analyze	VERB
bjp-70889	88	6	using	use	VERB
bjp-70889	88	7	imagej	imagej	ADJ
bjp-70889	88	8	software	software	NOUN
bjp-70889	88	9	(	(	PUNCT
bjp-70889	88	10	liu	liu	PROPN
bjp-70889	88	11	et	et	PROPN
bjp-70889	88	12	al	al	PROPN
bjp-70889	88	13	.	.	PROPN
bjp-70889	88	14	,	,	PUNCT
bjp-70889	88	15	2019	2019	NUM
bjp-70889	88	16	)	)	PUNCT
bjp-70889	88	17	.	.	PUNCT
bjp-70889	89	1	ripk1	ripk1	ADJ
bjp-70889	89	2	inhibitor	inhibitor	NOUN
bjp-70889	89	3	necrostatin	necrostatin	NOUN
bjp-70889	89	4	1	1	NUM
bjp-70889	89	5	(	(	PUNCT
bjp-70889	89	6	nec-1	nec-1	NOUN
bjp-70889	89	7	)	)	PUNCT
bjp-70889	89	8	,	,	PUNCT
bjp-70889	89	9	known	know	VERB
bjp-70889	89	10	as	as	ADP
bjp-70889	89	11	an	an	DET
bjp-70889	89	12	inhibitor	inhibitor	NOUN
bjp-70889	89	13	of	of	ADP
bjp-70889	89	14	ripk1	ripk1	NOUN
bjp-70889	89	15	,	,	PUNCT
bjp-70889	89	16	has	have	AUX
bjp-70889	89	17	demonstrated	demonstrate	VERB
bjp-70889	89	18	its	its	PRON
bjp-70889	89	19	ability	ability	NOUN
bjp-70889	89	20	to	to	PART
bjp-70889	89	21	inhibit	inhibit	VERB
bjp-70889	89	22	necroptosis	necroptosis	NOUN
bjp-70889	89	23	.	.	PUNCT
bjp-70889	90	1	to	to	PART
bjp-70889	90	2	further	far	ADV
bjp-70889	90	3	investigate	investigate	VERB
bjp-70889	90	4	the	the	DET
bjp-70889	90	5	role	role	NOUN
bjp-70889	90	6	of	of	ADP
bjp-70889	90	7	ripk1	ripk1	ADJ
bjp-70889	90	8	kinase	kinase	PROPN
bjp-70889	90	9	in	in	ADP
bjp-70889	90	10	berberine	berberine	NOUN
bjp-70889	90	11	-	-	PUNCT
bjp-70889	90	12	induced	induce	VERB
bjp-70889	90	13	necroptosis	necroptosis	NOUN
bjp-70889	90	14	,	,	PUNCT
bjp-70889	90	15	cck-8	cck-8	X
bjp-70889	90	16	,	,	PUNCT
bjp-70889	90	17	qrt	qrt	NOUN
bjp-70889	90	18	-	-	PUNCT
bjp-70889	90	19	pcr	pcr	ADJ
bjp-70889	90	20	,	,	PUNCT
bjp-70889	90	21	western	western	ADJ
bjp-70889	90	22	blot	blot	NOUN
bjp-70889	90	23	,	,	PUNCT
bjp-70889	90	24	and	and	CCONJ
bjp-70889	90	25	immunofluorescence	immunofluorescence	NOUN
bjp-70889	90	26	assays	assay	NOUN
bjp-70889	90	27	were	be	AUX
bjp-70889	90	28	conducted	conduct	VERB
bjp-70889	90	29	using	use	VERB
bjp-70889	90	30	ripk1	ripk1	ADJ
bjp-70889	90	31	inhibitor	inhibitor	NOUN
bjp-70889	90	32	nec-1	nec-1	NOUN
bjp-70889	90	33	.	.	PUNCT
bjp-70889	91	1	cells	cell	NOUN
bjp-70889	91	2	in	in	ADP
bjp-70889	91	3	the	the	DET
bjp-70889	91	4	inhibitor	inhibitor	NOUN
bjp-70889	91	5	group	group	NOUN
bjp-70889	91	6	,	,	PUNCT
bjp-70889	91	7	cultured	cultured	ADJ
bjp-70889	91	8	in	in	ADP
bjp-70889	91	9	96	96	NUM
bjp-70889	91	10	-	-	PUNCT
bjp-70889	91	11	well	well	NOUN
bjp-70889	91	12	,	,	PUNCT
bjp-70889	91	13	6	6	NUM
bjp-70889	91	14	-	-	PUNCT
bjp-70889	91	15	well	well	ADV
bjp-70889	91	16	,	,	PUNCT
bjp-70889	91	17	and	and	CCONJ
bjp-70889	91	18	24	24	NUM
bjp-70889	91	19	-	-	PUNCT
bjp-70889	91	20	well	well	NOUN
bjp-70889	91	21	plates	plate	NOUN
bjp-70889	91	22	,	,	PUNCT
bjp-70889	91	23	were	be	AUX
bjp-70889	91	24	pretreated	pretreate	VERB
bjp-70889	91	25	with	with	ADP
bjp-70889	91	26	2.5	2.5	NUM
bjp-70889	91	27	μm	μm	NOUN
bjp-70889	91	28	nec-1	nec-1	PRON
bjp-70889	91	29	(	(	PUNCT
bjp-70889	91	30	chen	chen	PROPN
bjp-70889	91	31	et	et	PROPN
bjp-70889	91	32	al	al	PROPN
bjp-70889	91	33	.	.	PROPN
bjp-70889	91	34	,	,	PUNCT
bjp-70889	91	35	2019	2019	NUM
bjp-70889	91	36	;	;	PUNCT
bjp-70889	91	37	shahsavari	shahsavari	PROPN
bjp-70889	91	38	et	et	PROPN
bjp-70889	91	39	al	al	PROPN
bjp-70889	91	40	.	.	PROPN
bjp-70889	91	41	,	,	PUNCT
bjp-70889	91	42	2016	2016	NUM
bjp-70889	91	43	)	)	PUNCT
bjp-70889	91	44	for	for	ADP
bjp-70889	91	45	8	8	NUM
bjp-70889	91	46	hours	hour	NOUN
bjp-70889	91	47	.	.	PUNCT
bjp-70889	92	1	after	after	ADP
bjp-70889	92	2	the	the	DET
bjp-70889	92	3	pretreatment	pretreatment	NOUN
bjp-70889	92	4	,	,	PUNCT
bjp-70889	92	5	cck-8	cck-8	X
bjp-70889	92	6	,	,	PUNCT
bjp-70889	92	7	qrt	qrt	NOUN
bjp-70889	92	8	-	-	PUNCT
bjp-70889	92	9	pcr	pcr	ADJ
bjp-70889	92	10	,	,	PUNCT
bjp-70889	92	11	western	western	ADJ
bjp-70889	92	12	blot	blot	NOUN
bjp-70889	92	13	,	,	PUNCT
bjp-70889	92	14	and	and	CCONJ
bjp-70889	92	15	immunofluorescence	immunofluorescence	NOUN
bjp-70889	92	16	experiments	experiment	NOUN
bjp-70889	92	17	were	be	AUX
bjp-70889	92	18	repeated	repeat	VERB
bjp-70889	92	19	following	follow	VERB
bjp-70889	92	20	the	the	DET
bjp-70889	92	21	procedures	procedure	NOUN
bjp-70889	92	22	outlined	outline	VERB
bjp-70889	92	23	above	above	ADV
bjp-70889	92	24	.	.	PUNCT
bjp-70889	93	1	statistical	statistical	ADJ
bjp-70889	93	2	analysis	analysis	NOUN
bjp-70889	93	3	data	datum	NOUN
bjp-70889	93	4	were	be	AUX
bjp-70889	93	5	expressed	express	VERB
bjp-70889	93	6	as	as	ADP
bjp-70889	93	7	mean	mean	PROPN
bjp-70889	93	8	±	±	NUM
bjp-70889	93	9	sem	sem	NOUN
bjp-70889	93	10	,	,	PUNCT
bjp-70889	93	11	and	and	CCONJ
bjp-70889	93	12	all	all	DET
bjp-70889	93	13	experiments	experiment	NOUN
bjp-70889	93	14	were	be	AUX
bjp-70889	93	15	performed	perform	VERB
bjp-70889	93	16	at	at	ADP
bjp-70889	93	17	least	least	ADV
bjp-70889	93	18	three	three	NUM
bjp-70889	93	19	times	time	NOUN
bjp-70889	93	20	.	.	PUNCT
bjp-70889	94	1	the	the	DET
bjp-70889	94	2	analysis	analysis	NOUN
bjp-70889	94	3	was	be	AUX
bjp-70889	94	4	performed	perform	VERB
bjp-70889	94	5	using	use	VERB
bjp-70889	94	6	graphpad	graphpad	NOUN
bjp-70889	94	7	prism	prism	NOUN
bjp-70889	94	8	8	8	NUM
bjp-70889	94	9	(	(	PUNCT
bjp-70889	94	10	graphpad	graphpad	NOUN
bjp-70889	94	11	software	software	NOUN
bjp-70889	94	12	,	,	PUNCT
bjp-70889	94	13	usa	usa	PROPN
bjp-70889	94	14	)	)	PUNCT
bjp-70889	94	15	.	.	PUNCT
bjp-70889	95	1	a	a	DET
bjp-70889	95	2	t	t	NOUN
bjp-70889	95	3	-	-	PUNCT
bjp-70889	95	4	test	test	NOUN
bjp-70889	95	5	was	be	AUX
bjp-70889	95	6	employed	employ	VERB
bjp-70889	95	7	to	to	PART
bjp-70889	95	8	assess	assess	VERB
bjp-70889	95	9	the	the	DET
bjp-70889	95	10	statistical	statistical	ADJ
bjp-70889	95	11	difference	difference	NOUN
bjp-70889	95	12	between	between	ADP
bjp-70889	95	13	the	the	DET
bjp-70889	95	14	two	two	NUM
bjp-70889	95	15	groups	group	NOUN
bjp-70889	95	16	,	,	PUNCT
bjp-70889	95	17	while	while	SCONJ
bjp-70889	95	18	one	one	NUM
bjp-70889	95	19	-	-	PUNCT
bjp-70889	95	20	way	way	NOUN
bjp-70889	95	21	analysis	analysis	NOUN
bjp-70889	95	22	of	of	ADP
bjp-70889	95	23	variance	variance	NOUN
bjp-70889	95	24	was	be	AUX
bjp-70889	95	25	used	use	VERB
bjp-70889	95	26	for	for	ADP
bjp-70889	95	27	comparisons	comparison	NOUN
bjp-70889	95	28	among	among	ADP
bjp-70889	95	29	multiple	multiple	ADJ
bjp-70889	95	30	groups	group	NOUN
bjp-70889	95	31	,	,	PUNCT
bjp-70889	95	32	followed	follow	VERB
bjp-70889	95	33	by	by	ADP
bjp-70889	95	34	dunnett	dunnett	PROPN
bjp-70889	95	35	post	post	X
bjp-70889	95	36	hoc	hoc	X
bjp-70889	95	37	test	test	NOUN
bjp-70889	95	38	.	.	PUNCT
bjp-70889	96	1	results	result	NOUN
bjp-70889	96	2	necroptosis	necroptosis	NOUN
bjp-70889	96	3	of	of	ADP
bjp-70889	96	4	h8	h8	PROPN
bjp-70889	96	5	cells	cell	NOUN
bjp-70889	96	6	figure	figure	VERB
bjp-70889	96	7	1	1	NUM
bjp-70889	96	8	illustrates	illustrate	VERB
bjp-70889	96	9	the	the	DET
bjp-70889	96	10	cytotoxic	cytotoxic	ADJ
bjp-70889	96	11	effects	effect	NOUN
bjp-70889	96	12	of	of	ADP
bjp-70889	96	13	berberine	berberine	NOUN
bjp-70889	96	14	on	on	ADP
bjp-70889	96	15	h8	h8	PROPN
bjp-70889	96	16	cells	cell	NOUN
bjp-70889	96	17	,	,	PUNCT
bjp-70889	96	18	revealing	reveal	VERB
bjp-70889	96	19	a	a	DET
bjp-70889	96	20	substantial	substantial	ADJ
bjp-70889	96	21	reduction	reduction	NOUN
bjp-70889	96	22	in	in	ADP
bjp-70889	96	23	cell	cell	NOUN
bjp-70889	96	24	viability	viability	NOUN
bjp-70889	96	25	with	with	ADP
bjp-70889	96	26	increasing	increase	VERB
bjp-70889	96	27	intervention	intervention	NOUN
bjp-70889	96	28	time	time	NOUN
bjp-70889	96	29	and	and	CCONJ
bjp-70889	96	30	dosage	dosage	NOUN
bjp-70889	96	31	(	(	PUNCT
bjp-70889	96	32	p<0.05	p<0.05	NOUN
bjp-70889	96	33	)	)	PUNCT
bjp-70889	96	34	.	.	PUNCT
bjp-70889	97	1	the	the	DET
bjp-70889	97	2	ic50	ic50	PROPN
bjp-70889	97	3	of	of	ADP
bjp-70889	97	4	berberine	berberine	NOUN
bjp-70889	97	5	,	,	PUNCT
bjp-70889	97	6	observed	observe	VERB
bjp-70889	97	7	after	after	ADP
bjp-70889	97	8	72	72	NUM
bjp-70889	97	9	hours	hour	NOUN
bjp-70889	97	10	of	of	ADP
bjp-70889	97	11	intervention	intervention	NOUN
bjp-70889	97	12	at	at	ADP
bjp-70889	97	13	a	a	DET
bjp-70889	97	14	concentra	concentra	ADJ
bjp-70889	97	15	tion	tion	NOUN
bjp-70889	97	16	of	of	ADP
bjp-70889	97	17	40	40	NUM
bjp-70889	97	18	μm	μm	NUM
bjp-70889	97	19	,	,	PUNCT
bjp-70889	97	20	indicated	indicate	VERB
bjp-70889	97	21	a	a	DET
bjp-70889	97	22	significant	significant	ADJ
bjp-70889	97	23	decrease	decrease	NOUN
bjp-70889	97	24	in	in	ADP
bjp-70889	97	25	the	the	DET
bjp-70889	97	26	cell	cell	NOUN
bjp-70889	97	27	viability	viability	NOUN
bjp-70889	97	28	by	by	ADP
bjp-70889	97	29	approximately	approximately	ADV
bjp-70889	97	30	50	50	NUM
bjp-70889	97	31	%	%	NOUN
bjp-70889	97	32	.	.	PUNCT
bjp-70889	98	1	the	the	DET
bjp-70889	98	2	experimental	experimental	ADJ
bjp-70889	98	3	results	result	NOUN
bjp-70889	98	4	highlighted	highlight	VERB
bjp-70889	98	5	concentrationdependent	concentrationdependent	NOUN
bjp-70889	98	6	(	(	PUNCT
bjp-70889	98	7	0	0	NUM
bjp-70889	98	8	-	-	SYM
bjp-70889	98	9	100	100	NUM
bjp-70889	98	10	μm	μm	NUM
bjp-70889	98	11	)	)	PUNCT
bjp-70889	98	12	and	and	CCONJ
bjp-70889	98	13	time	time	NOUN
bjp-70889	98	14	-	-	PUNCT
bjp-70889	98	15	dependent	dependent	ADJ
bjp-70889	98	16	(	(	PUNCT
bjp-70889	98	17	24	24	NUM
bjp-70889	98	18	-	-	SYM
bjp-70889	98	19	72	72	NUM
bjp-70889	98	20	hours	hour	NOUN
bjp-70889	98	21	)	)	PUNCT
bjp-70889	98	22	characteristics	characteristic	NOUN
bjp-70889	98	23	of	of	ADP
bjp-70889	98	24	berberine	berberine	NOUN
bjp-70889	98	25	-	-	PUNCT
bjp-70889	98	26	induced	induce	VERB
bjp-70889	98	27	cytotoxic	cytotoxic	ADJ
bjp-70889	98	28	and	and	CCONJ
bjp-70889	98	29	apoptotic	apoptotic	ADJ
bjp-70889	98	30	effects	effect	NOUN
bjp-70889	98	31	on	on	ADP
bjp-70889	98	32	h8	h8	PROPN
bjp-70889	98	33	cells	cell	NOUN
bjp-70889	98	34	.	.	PUNCT
bjp-70889	99	1	consequently	consequently	ADV
bjp-70889	99	2	,	,	PUNCT
bjp-70889	99	3	subsequent	subsequent	ADJ
bjp-70889	99	4	experimental	experimental	ADJ
bjp-70889	99	5	groups	group	NOUN
bjp-70889	99	6	were	be	AUX
bjp-70889	99	7	treated	treat	VERB
bjp-70889	99	8	with	with	ADP
bjp-70889	99	9	a	a	DET
bjp-70889	99	10	low	low	ADJ
bjp-70889	99	11	dose	dose	NOUN
bjp-70889	99	12	(	(	PUNCT
bjp-70889	99	13	20	20	NUM
bjp-70889	99	14	μm	μm	NUM
bjp-70889	99	15	)	)	PUNCT
bjp-70889	99	16	,	,	PUNCT
bjp-70889	99	17	medium	medium	NOUN
bjp-70889	99	18	dose	dose	NOUN
bjp-70889	99	19	(	(	PUNCT
bjp-70889	99	20	40	40	NUM
bjp-70889	99	21	μm	μm	NUM
bjp-70889	99	22	)	)	PUNCT
bjp-70889	99	23	,	,	PUNCT
bjp-70889	99	24	and	and	CCONJ
bjp-70889	99	25	high	high	ADJ
bjp-70889	99	26	dose	dose	NOUN
bjp-70889	99	27	(	(	PUNCT
bjp-70889	99	28	80	80	NUM
bjp-70889	99	29	μm	μm	NUM
bjp-70889	99	30	)	)	PUNCT
bjp-70889	99	31	of	of	ADP
bjp-70889	99	32	berberine	berberine	NOUN
bjp-70889	99	33	for	for	ADP
bjp-70889	99	34	72	72	NUM
bjp-70889	99	35	hours	hour	NOUN
bjp-70889	99	36	intervention	intervention	NOUN
bjp-70889	99	37	.	.	PUNCT
bjp-70889	100	1	up	up	ADP
bjp-70889	100	2	-	-	PUNCT
bjp-70889	100	3	regulation	regulation	NOUN
bjp-70889	100	4	of	of	ADP
bjp-70889	100	5	ripk1	ripk1	ADJ
bjp-70889	100	6	kinase	kinase	NOUN
bjp-70889	100	7	expression	expression	NOUN
bjp-70889	100	8	as	as	SCONJ
bjp-70889	100	9	shown	show	VERB
bjp-70889	100	10	in	in	ADP
bjp-70889	100	11	figure	figure	NOUN
bjp-70889	100	12	2	2	NUM
bjp-70889	100	13	,	,	PUNCT
bjp-70889	100	14	berberine	berberine	NOUN
bjp-70889	100	15	demonstrated	demonstrate	VERB
bjp-70889	100	16	a	a	DET
bjp-70889	100	17	figure	figure	NOUN
bjp-70889	100	18	1：the	1：the	PRON
bjp-70889	100	19	cck-8	cck-8	PUNCT
bjp-70889	100	20	assay	assay	NOUN
bjp-70889	100	21	was	be	AUX
bjp-70889	100	22	used	use	VERB
bjp-70889	100	23	to	to	PART
bjp-70889	100	24	assess	assess	VERB
bjp-70889	100	25	whether	whether	SCONJ
bjp-70889	100	26	berberine	berberine	NOUN
bjp-70889	100	27	inhibits	inhibit	VERB
bjp-70889	100	28	cell	cell	NOUN
bjp-70889	100	29	proliferation	proliferation	NOUN
bjp-70889	100	30	at	at	ADP
bjp-70889	100	31	different	different	ADJ
bjp-70889	100	32	time	time	NOUN
bjp-70889	100	33	or	or	CCONJ
bjp-70889	100	34	dose	dose	NOUN
bjp-70889	100	35	points	point	NOUN
bjp-70889	100	36	.	.	PUNCT
bjp-70889	101	1	data	datum	NOUN
bjp-70889	101	2	are	be	AUX
bjp-70889	101	3	expressed	express	VERB
bjp-70889	101	4	as	as	ADP
bjp-70889	101	5	mean	mean	PROPN
bjp-70889	101	6	±	±	NUM
bjp-70889	101	7	sem	sem	NOUN
bjp-70889	101	8	.	.	PUNCT
bjp-70889	102	1	compared	compare	VERB
bjp-70889	102	2	to	to	ADP
bjp-70889	102	3	the	the	DET
bjp-70889	102	4	control	control	NOUN
bjp-70889	102	5	group	group	NOUN
bjp-70889	102	6	,	,	PUNCT
bjp-70889	102	7	ap＜0.05，bp＜0.01	ap＜0.05，bp＜0.01	PROPN
bjp-70889	102	8	;	;	PUNCT
bjp-70889	102	9	compared	compare	VERB
bjp-70889	102	10	to	to	ADP
bjp-70889	102	11	the	the	DET
bjp-70889	102	12	control	control	NOUN
bjp-70889	102	13	group	group	NOUN
bjp-70889	102	14	,	,	PUNCT
bjp-70889	102	15	*	*	PUNCT
bjp-70889	102	16	*	*	PUNCT
bjp-70889	102	17	p＜0.01	p＜0.01	ADJ
bjp-70889	102	18	figure	figure	NOUN
bjp-70889	102	19	2：immunofluorescence	2：immunofluorescence	NUM
bjp-70889	102	20	assay	assay	NOUN
bjp-70889	102	21	was	be	AUX
bjp-70889	102	22	used	use	VERB
bjp-70889	102	23	to	to	PART
bjp-70889	102	24	assess	assess	VERB
bjp-70889	102	25	the	the	DET
bjp-70889	102	26	expression	expression	NOUN
bjp-70889	102	27	of	of	ADP
bjp-70889	102	28	ripk1	ripk1	NOUN
bjp-70889	102	29	in	in	ADP
bjp-70889	102	30	h8	h8	PROPN
bjp-70889	102	31	cells	cell	NOUN
bjp-70889	102	32	treated	treat	VERB
bjp-70889	102	33	with	with	ADP
bjp-70889	102	34	berberine	berberine	NOUN
bjp-70889	102	35	at	at	ADP
bjp-70889	102	36	different	different	ADJ
bjp-70889	102	37	concentrations	concentration	NOUN
bjp-70889	102	38	.	.	PUNCT
bjp-70889	103	1	data	datum	NOUN
bjp-70889	103	2	are	be	AUX
bjp-70889	103	3	expressed	express	VERB
bjp-70889	103	4	as	as	ADP
bjp-70889	103	5	mean	mean	PROPN
bjp-70889	103	6	±	±	NUM
bjp-70889	103	7	sem	sem	NOUN
bjp-70889	103	8	.	.	PUNCT
bjp-70889	104	1	compared	compare	VERB
bjp-70889	104	2	to	to	ADP
bjp-70889	104	3	the	the	DET
bjp-70889	104	4	control	control	NOUN
bjp-70889	104	5	group	group	NOUN
bjp-70889	104	6	,	,	PUNCT
bjp-70889	104	7	ap＜0.05;bp＜	ap＜0.05;bp＜	PUNCT
bjp-70889	104	8	0.01	0.01	NUM
bjp-70889	104	9	24	24	NUM
bjp-70889	104	10	hours	hour	NOUN
bjp-70889	104	11	48	48	NUM
bjp-70889	104	12	hours	hour	NOUN
bjp-70889	104	13	72	72	NUM
bjp-70889	104	14	hours	hour	NOUN
bjp-70889	104	15	berberine	berberine	NOUN
bjp-70889	104	16	(	(	PUNCT
bjp-70889	104	17	µm	µm	NOUN
bjp-70889	104	18	)	)	PUNCT
bjp-70889	104	19	c	c	NOUN
bjp-70889	105	1	e	e	NOUN
bjp-70889	105	2	ll	ll	AUX
bjp-70889	105	3	v	v	PROPN
bjp-70889	105	4	ia	ia	PROPN
bjp-70889	105	5	b	b	PROPN
bjp-70889	105	6	il	il	PROPN
bjp-70889	105	7	it	it	PRON
bjp-70889	105	8	y	y	PROPN
bjp-70889	105	9	(	(	PUNCT
bjp-70889	105	10	%	%	INTJ
bjp-70889	105	11	)	)	PUNCT
bjp-70889	105	12	berberine	berberine	NOUN
bjp-70889	105	13	(	(	PUNCT
bjp-70889	105	14	µm	µm	NOUN
bjp-70889	105	15	)	)	PUNCT
bjp-70889	105	16	berberine	berberine	NOUN
bjp-70889	105	17	0	0	NUM
bjp-70889	105	18	20	20	NUM
bjp-70889	105	19	40	40	NUM
bjp-70889	105	20	80	80	NUM
bjp-70889	105	21	(	(	PUNCT
bjp-70889	105	22	µm	µm	NOUN
bjp-70889	105	23	)	)	PUNCT
bjp-70889	105	24	a	a	DET
bjp-70889	105	25	b	b	NOUN
bjp-70889	105	26	dapi	dapi	ADJ
bjp-70889	105	27	dapi	dapi	ADJ
bjp-70889	105	28	ripk1	ripk1	NOUN
bjp-70889	105	29	merge	merge	VERB
bjp-70889	105	30	a	a	DET
bjp-70889	105	31	b	b	PROPN
bjp-70889	105	32	b	b	PROPN
bjp-70889	105	33	a	a	DET
bjp-70889	105	34	a	a	DET
bjp-70889	105	35	a	a	DET
bjp-70889	105	36	b	b	PROPN
bjp-70889	105	37	16	16	NUM
bjp-70889	105	38	bangladesh	bangladesh	NOUN
bjp-70889	105	39	j	j	PROPN
bjp-70889	105	40	pharmacol	pharmacol	PROPN
bjp-70889	105	41	2024	2024	NUM
bjp-70889	105	42	;	;	PUNCT
bjp-70889	105	43	19	19	NUM
bjp-70889	105	44	:	:	SYM
bjp-70889	105	45	13	13	NUM
bjp-70889	105	46	-	-	SYM
bjp-70889	105	47	22	22	NUM
bjp-70889	105	48	significant	significant	ADJ
bjp-70889	105	49	increase	increase	NOUN
bjp-70889	105	50	in	in	ADP
bjp-70889	105	51	the	the	DET
bjp-70889	105	52	expression	expression	NOUN
bjp-70889	105	53	level	level	NOUN
bjp-70889	105	54	of	of	ADP
bjp-70889	105	55	ripk1	ripk1	NOUN
bjp-70889	105	56	compared	compare	VERB
bjp-70889	105	57	to	to	ADP
bjp-70889	105	58	the	the	DET
bjp-70889	105	59	control	control	NOUN
bjp-70889	105	60	group	group	NOUN
bjp-70889	105	61	(	(	PUNCT
bjp-70889	105	62	p<0.05	p<0.05	PROPN
bjp-70889	105	63	)	)	PUNCT
bjp-70889	105	64	.	.	PUNCT
bjp-70889	106	1	this	this	DET
bjp-70889	106	2	result	result	NOUN
bjp-70889	106	3	underscores	underscore	VERB
bjp-70889	106	4	the	the	DET
bjp-70889	106	5	pronounced	pronounce	VERB
bjp-70889	106	6	impact	impact	NOUN
bjp-70889	106	7	of	of	ADP
bjp-70889	106	8	berberine	berberine	NOUN
bjp-70889	106	9	on	on	ADP
bjp-70889	106	10	ripk1	ripk1	ADJ
bjp-70889	106	11	expression	expression	NOUN
bjp-70889	106	12	in	in	ADP
bjp-70889	106	13	h8	h8	PROPN
bjp-70889	106	14	cells	cell	NOUN
bjp-70889	106	15	.	.	PUNCT
bjp-70889	107	1	up	up	ADP
bjp-70889	107	2	-	-	PUNCT
bjp-70889	107	3	regulation	regulation	NOUN
bjp-70889	107	4	of	of	ADP
bjp-70889	107	5	mrna	mrna	PROPN
bjp-70889	107	6	expression	expression	NOUN
bjp-70889	107	7	levels	level	NOUN
bjp-70889	107	8	of	of	ADP
bjp-70889	107	9	ripk1	ripk1	NOUN
bjp-70889	107	10	and	and	CCONJ
bjp-70889	107	11	mlkl	mlkl	PROPN
bjp-70889	107	12	as	as	SCONJ
bjp-70889	107	13	illustrated	illustrate	VERB
bjp-70889	107	14	in	in	ADP
bjp-70889	107	15	figure	figure	NOUN
bjp-70889	107	16	3a	3a	NUM
bjp-70889	107	17	-	-	SYM
bjp-70889	107	18	b	b	NOUN
bjp-70889	107	19	,	,	PUNCT
bjp-70889	107	20	the	the	DET
bjp-70889	107	21	intervention	intervention	NOUN
bjp-70889	107	22	groups	group	NOUN
bjp-70889	107	23	treated	treat	VERB
bjp-70889	107	24	with	with	ADP
bjp-70889	107	25	low	low	ADJ
bjp-70889	107	26	,	,	PUNCT
bjp-70889	107	27	medium	medium	ADJ
bjp-70889	107	28	,	,	PUNCT
bjp-70889	107	29	and	and	CCONJ
bjp-70889	107	30	high	high	ADJ
bjp-70889	107	31	doses	dose	NOUN
bjp-70889	107	32	of	of	ADP
bjp-70889	107	33	berberine	berberine	NOUN
bjp-70889	107	34	showed	show	VERB
bjp-70889	107	35	a	a	DET
bjp-70889	107	36	noteworthy	noteworthy	ADJ
bjp-70889	107	37	increase	increase	NOUN
bjp-70889	107	38	in	in	ADP
bjp-70889	107	39	ripk1	ripk1	NOUN
bjp-70889	107	40	and	and	CCONJ
bjp-70889	107	41	mlkl	mlkl	VERB
bjp-70889	107	42	mrna	mrna	PROPN
bjp-70889	107	43	expression	expression	NOUN
bjp-70889	107	44	levels	level	NOUN
bjp-70889	107	45	compared	compare	VERB
bjp-70889	107	46	to	to	ADP
bjp-70889	107	47	the	the	DET
bjp-70889	107	48	control	control	NOUN
bjp-70889	107	49	group	group	NOUN
bjp-70889	107	50	(	(	PUNCT
bjp-70889	107	51	p<0.05	p<0.05	PROPN
bjp-70889	107	52	)	)	PUNCT
bjp-70889	107	53	.	.	PUNCT
bjp-70889	108	1	up	up	ADP
bjp-70889	108	2	-	-	PUNCT
bjp-70889	108	3	regulation	regulation	NOUN
bjp-70889	108	4	of	of	ADP
bjp-70889	108	5	protein	protein	NOUN
bjp-70889	108	6	expression	expression	NOUN
bjp-70889	108	7	levels	level	NOUN
bjp-70889	108	8	of	of	ADP
bjp-70889	108	9	ripk1	ripk1	NOUN
bjp-70889	108	10	and	and	CCONJ
bjp-70889	108	11	mlkl	mlkl	VERB
bjp-70889	108	12	western	western	ADJ
bjp-70889	108	13	blot	blot	NOUN
bjp-70889	108	14	was	be	AUX
bjp-70889	108	15	used	use	VERB
bjp-70889	108	16	to	to	PART
bjp-70889	108	17	investigate	investigate	VERB
bjp-70889	108	18	the	the	DET
bjp-70889	108	19	protein	protein	NOUN
bjp-70889	108	20	expression	expression	NOUN
bjp-70889	108	21	levels	level	NOUN
bjp-70889	108	22	of	of	ADP
bjp-70889	108	23	key	key	ADJ
bjp-70889	108	24	markers	marker	NOUN
bjp-70889	108	25	of	of	ADP
bjp-70889	108	26	necroptosis	necroptosis	NOUN
bjp-70889	108	27	in	in	ADP
bjp-70889	108	28	h8	h8	PROPN
bjp-70889	108	29	cells	cell	NOUN
bjp-70889	108	30	caused	cause	VERB
bjp-70889	108	31	by	by	ADP
bjp-70889	108	32	berberine	berberine	NOUN
bjp-70889	108	33	.	.	PUNCT
bjp-70889	109	1	as	as	SCONJ
bjp-70889	109	2	depicted	depict	VERB
bjp-70889	109	3	in	in	ADP
bjp-70889	109	4	figure	figure	NOUN
bjp-70889	109	5	3c	3c	NUM
bjp-70889	109	6	-	-	SYM
bjp-70889	109	7	d	d	NOUN
bjp-70889	109	8	,	,	PUNCT
bjp-70889	109	9	compared	compare	VERB
bjp-70889	109	10	to	to	ADP
bjp-70889	109	11	the	the	DET
bjp-70889	109	12	control	control	NOUN
bjp-70889	109	13	group	group	NOUN
bjp-70889	109	14	,	,	PUNCT
bjp-70889	109	15	the	the	DET
bjp-70889	109	16	intervention	intervention	NOUN
bjp-70889	109	17	groups	group	NOUN
bjp-70889	109	18	treated	treat	VERB
bjp-70889	109	19	with	with	ADP
bjp-70889	109	20	low	low	ADJ
bjp-70889	109	21	,	,	PUNCT
bjp-70889	109	22	medium	medium	ADJ
bjp-70889	109	23	,	,	PUNCT
bjp-70889	109	24	and	and	CCONJ
bjp-70889	109	25	high	high	ADJ
bjp-70889	109	26	concentrations	concentration	NOUN
bjp-70889	109	27	of	of	ADP
bjp-70889	109	28	berberine	berberine	NOUN
bjp-70889	109	29	exhibited	exhibit	VERB
bjp-70889	109	30	a	a	DET
bjp-70889	109	31	significant	significant	ADJ
bjp-70889	109	32	increase	increase	NOUN
bjp-70889	109	33	in	in	ADP
bjp-70889	109	34	ripk1	ripk1	ADJ
bjp-70889	109	35	protein	protein	NOUN
bjp-70889	109	36	expression	expression	NOUN
bjp-70889	109	37	and	and	CCONJ
bjp-70889	109	38	the	the	DET
bjp-70889	109	39	p	p	NOUN
bjp-70889	109	40	-	-	PUNCT
bjp-70889	109	41	mlkl	mlkl	VERB
bjp-70889	109	42	/	/	SYM
bjp-70889	109	43	mlkl	mlkl	NOUN
bjp-70889	109	44	ratio	ratio	NOUN
bjp-70889	109	45	(	(	PUNCT
bjp-70889	109	46	p<0.05	p<0.05	NOUN
bjp-70889	109	47	)	)	PUNCT
bjp-70889	109	48	.	.	PUNCT
bjp-70889	110	1	these	these	DET
bjp-70889	110	2	findings	finding	NOUN
bjp-70889	110	3	underscore	underscore	VERB
bjp-70889	110	4	a	a	DET
bjp-70889	110	5	statistically	statistically	ADV
bjp-70889	110	6	significant	significant	ADJ
bjp-70889	110	7	difference	difference	NOUN
bjp-70889	110	8	in	in	ADP
bjp-70889	110	9	the	the	DET
bjp-70889	110	10	levels	level	NOUN
bjp-70889	110	11	of	of	ADP
bjp-70889	110	12	these	these	DET
bjp-70889	110	13	key	key	ADJ
bjp-70889	110	14	apoptotic	apoptotic	ADJ
bjp-70889	110	15	markers	marker	NOUN
bjp-70889	110	16	following	follow	VERB
bjp-70889	110	17	berberine	berberine	NOUN
bjp-70889	110	18	intervention	intervention	NOUN
bjp-70889	110	19	.	.	PUNCT
bjp-70889	111	1	notably	notably	ADV
bjp-70889	111	2	,	,	PUNCT
bjp-70889	111	3	these	these	DET
bjp-70889	111	4	results	result	NOUN
bjp-70889	111	5	align	align	VERB
bjp-70889	111	6	with	with	ADP
bjp-70889	111	7	the	the	DET
bjp-70889	111	8	observations	observation	NOUN
bjp-70889	111	9	from	from	ADP
bjp-70889	111	10	qrt	qrt	ADJ
bjp-70889	111	11	-	-	PUNCT
bjp-70889	111	12	pcr	pcr	ADJ
bjp-70889	111	13	analysis	analysis	NOUN
bjp-70889	111	14	.	.	PUNCT
bjp-70889	112	1	partial	partial	ADJ
bjp-70889	112	2	inhibition	inhibition	NOUN
bjp-70889	112	3	of	of	ADP
bjp-70889	112	4	necroptosis	necroptosis	NOUN
bjp-70889	112	5	by	by	ADP
bjp-70889	112	6	nec-1	nec-1	PRON
bjp-70889	112	7	as	as	SCONJ
bjp-70889	112	8	shown	show	VERB
bjp-70889	112	9	in	in	ADP
bjp-70889	112	10	figure	figure	NOUN
bjp-70889	112	11	4a	4a	NOUN
bjp-70889	112	12	,	,	PUNCT
bjp-70889	112	13	the	the	DET
bjp-70889	112	14	cck-8	cck-8	PUNCT
bjp-70889	112	15	assay	assay	NOUN
bjp-70889	112	16	results	result	NOUN
bjp-70889	112	17	indicated	indicate	VERB
bjp-70889	112	18	a	a	DET
bjp-70889	112	19	significant	significant	ADJ
bjp-70889	112	20	decrease	decrease	NOUN
bjp-70889	112	21	in	in	ADP
bjp-70889	112	22	cell	cell	NOUN
bjp-70889	112	23	viability	viability	NOUN
bjp-70889	112	24	after	after	ADP
bjp-70889	112	25	72	72	NUM
bjp-70889	112	26	hours	hour	NOUN
bjp-70889	112	27	of	of	ADP
bjp-70889	112	28	treatment	treatment	NOUN
bjp-70889	112	29	with	with	ADP
bjp-70889	112	30	40	40	NUM
bjp-70889	112	31	μm	μm	NOUN
bjp-70889	112	32	berberine	berberine	NOUN
bjp-70889	112	33	compared	compare	VERB
bjp-70889	112	34	to	to	ADP
bjp-70889	112	35	the	the	DET
bjp-70889	112	36	control	control	NOUN
bjp-70889	112	37	group	group	NOUN
bjp-70889	112	38	(	(	PUNCT
bjp-70889	112	39	p<0.01	p<0.01	PROPN
bjp-70889	112	40	)	)	PUNCT
bjp-70889	112	41	.	.	PUNCT
bjp-70889	113	1	however	however	ADV
bjp-70889	113	2	,	,	PUNCT
bjp-70889	113	3	co	co	NOUN
bjp-70889	113	4	-	-	NOUN
bjp-70889	113	5	treatment	treatment	NOUN
bjp-70889	113	6	with	with	ADP
bjp-70889	113	7	ripk1	ripk1	ADJ
bjp-70889	113	8	inhibitor	inhibitor	NOUN
bjp-70889	113	9	,	,	PUNCT
bjp-70889	113	10	nec-1	nec-1	PUNCT
bjp-70889	113	11	(	(	PUNCT
bjp-70889	113	12	2.5	2.5	NUM
bjp-70889	113	13	μm	μm	NOUN
bjp-70889	113	14	)	)	PUNCT
bjp-70889	113	15	,	,	PUNCT
bjp-70889	113	16	led	lead	VERB
bjp-70889	113	17	to	to	ADP
bjp-70889	113	18	an	an	DET
bjp-70889	113	19	increase	increase	NOUN
bjp-70889	113	20	in	in	ADP
bjp-70889	113	21	cell	cell	NOUN
bjp-70889	113	22	viability	viability	NOUN
bjp-70889	113	23	(	(	PUNCT
bjp-70889	113	24	p<0.05	p<0.05	NOUN
bjp-70889	113	25	)	)	PUNCT
bjp-70889	113	26	.	.	PUNCT
bjp-70889	114	1	the	the	DET
bjp-70889	114	2	qrt	qrt	ADJ
bjp-70889	114	3	-	-	PUNCT
bjp-70889	114	4	pcr	pcr	ADJ
bjp-70889	114	5	results	result	NOUN
bjp-70889	114	6	(	(	PUNCT
bjp-70889	114	7	figure	figure	VERB
bjp-70889	114	8	4b	4b	PROPN
bjp-70889	114	9	-	-	PUNCT
bjp-70889	114	10	c	c	NOUN
bjp-70889	114	11	)	)	PUNCT
bjp-70889	114	12	demonstrated	demonstrate	VERB
bjp-70889	114	13	a	a	DET
bjp-70889	114	14	significant	significant	ADJ
bjp-70889	114	15	up	up	ADJ
bjp-70889	114	16	-	-	PUNCT
bjp-70889	114	17	regulation	regulation	NOUN
bjp-70889	114	18	in	in	ADP
bjp-70889	114	19	the	the	DET
bjp-70889	114	20	expression	expression	NOUN
bjp-70889	114	21	of	of	ADP
bjp-70889	114	22	ripk1	ripk1	NOUN
bjp-70889	114	23	and	and	CCONJ
bjp-70889	114	24	mlkl	mlkl	PROPN
bjp-70889	114	25	mrna	mrna	PROPN
bjp-70889	114	26	after	after	ADP
bjp-70889	114	27	72	72	NUM
bjp-70889	114	28	hours	hour	NOUN
bjp-70889	114	29	of	of	ADP
bjp-70889	114	30	intervention	intervention	NOUN
bjp-70889	114	31	with	with	ADP
bjp-70889	114	32	40	40	NUM
bjp-70889	114	33	μm	μm	NOUN
bjp-70889	114	34	berberine	berberine	NOUN
bjp-70889	114	35	(	(	PUNCT
bjp-70889	114	36	p<0.01	p<0.01	PROPN
bjp-70889	114	37	)	)	PUNCT
bjp-70889	114	38	.	.	PUNCT
bjp-70889	115	1	conversely	conversely	ADV
bjp-70889	115	2	,	,	PUNCT
bjp-70889	115	3	the	the	DET
bjp-70889	115	4	addition	addition	NOUN
bjp-70889	115	5	of	of	ADP
bjp-70889	115	6	the	the	DET
bjp-70889	115	7	ripk1	ripk1	ADJ
bjp-70889	115	8	kinase	kinase	PROPN
bjp-70889	115	9	inhibitor	inhibitor	NOUN
bjp-70889	115	10	(	(	PUNCT
bjp-70889	115	11	2.5μm	2.5μm	NUM
bjp-70889	115	12	nec-1	nec-1	PRON
bjp-70889	115	13	)	)	PUNCT
bjp-70889	115	14	resulted	result	VERB
bjp-70889	115	15	in	in	ADP
bjp-70889	115	16	a	a	DET
bjp-70889	115	17	significant	significant	ADJ
bjp-70889	115	18	decrease	decrease	NOUN
bjp-70889	115	19	in	in	ADP
bjp-70889	115	20	ripk1	ripk1	NOUN
bjp-70889	115	21	and	and	CCONJ
bjp-70889	115	22	mlkl	mlkl	VERB
bjp-70889	115	23	mrna	mrna	NOUN
bjp-70889	115	24	expression	expression	NOUN
bjp-70889	115	25	(	(	PUNCT
bjp-70889	115	26	p<0.01	p<0.01	PROPN
bjp-70889	115	27	)	)	PUNCT
bjp-70889	115	28	.	.	PUNCT
bjp-70889	116	1	consistent	consistent	ADJ
bjp-70889	116	2	with	with	ADP
bjp-70889	116	3	the	the	DET
bjp-70889	116	4	qrt	qrt	ADJ
bjp-70889	116	5	-	-	PUNCT
bjp-70889	116	6	pcr	pcr	ADJ
bjp-70889	116	7	findings	finding	NOUN
bjp-70889	116	8	,	,	PUNCT
bjp-70889	116	9	western	western	ADJ
bjp-70889	116	10	blot	blot	NOUN
bjp-70889	116	11	results	result	NOUN
bjp-70889	116	12	(	(	PUNCT
bjp-70889	116	13	figure	figure	VERB
bjp-70889	116	14	4d	4d	NUM
bjp-70889	116	15	-	-	PUNCT
bjp-70889	116	16	f	f	NOUN
bjp-70889	116	17	)	)	PUNCT
bjp-70889	116	18	revealed	reveal	VERB
bjp-70889	116	19	parallel	parallel	ADJ
bjp-70889	116	20	changes	change	NOUN
bjp-70889	116	21	in	in	ADP
bjp-70889	116	22	protein	protein	NOUN
bjp-70889	116	23	expressions	expression	NOUN
bjp-70889	116	24	levels	level	NOUN
bjp-70889	116	25	.	.	PUNCT
bjp-70889	117	1	moreover	moreover	ADV
bjp-70889	117	2	,	,	PUNCT
bjp-70889	117	3	immunofluorescence	immunofluorescence	NOUN
bjp-70889	117	4	results	result	NOUN
bjp-70889	117	5	demonstrated	demonstrate	VERB
bjp-70889	117	6	a	a	DET
bjp-70889	117	7	significant	significant	ADJ
bjp-70889	117	8	up	up	NOUN
bjp-70889	117	9	-	-	PUNCT
bjp-70889	117	10	regulation	regulation	NOUN
bjp-70889	117	11	of	of	ADP
bjp-70889	117	12	ripk1	ripk1	ADJ
bjp-70889	117	13	expression	expression	NOUN
bjp-70889	117	14	after	after	ADP
bjp-70889	117	15	72	72	NUM
bjp-70889	117	16	hours	hour	NOUN
bjp-70889	117	17	of	of	ADP
bjp-70889	117	18	treatment	treatment	NOUN
bjp-70889	117	19	with	with	ADP
bjp-70889	117	20	40	40	NUM
bjp-70889	117	21	μm	μm	NOUN
bjp-70889	117	22	berberine	berberine	NOUN
bjp-70889	117	23	compared	compare	VERB
bjp-70889	117	24	to	to	ADP
bjp-70889	117	25	control	control	NOUN
bjp-70889	117	26	cells	cell	NOUN
bjp-70889	117	27	(	(	PUNCT
bjp-70889	117	28	p<0.05	p<0.05	NOUN
bjp-70889	117	29	)	)	PUNCT
bjp-70889	117	30	.	.	PUNCT
bjp-70889	118	1	however	however	ADV
bjp-70889	118	2	,	,	PUNCT
bjp-70889	118	3	co	co	NOUN
bjp-70889	118	4	-	-	NOUN
bjp-70889	118	5	treatment	treatment	NOUN
bjp-70889	118	6	with	with	ADP
bjp-70889	118	7	nec-1	nec-1	PRON
bjp-70889	118	8	(	(	PUNCT
bjp-70889	118	9	2.5	2.5	NUM
bjp-70889	118	10	μm	μm	NOUN
bjp-70889	118	11	)	)	PUNCT
bjp-70889	118	12	resulted	result	VERB
bjp-70889	118	13	in	in	ADP
bjp-70889	118	14	a	a	DET
bjp-70889	118	15	decrease	decrease	NOUN
bjp-70889	118	16	in	in	ADP
bjp-70889	118	17	ripk1	ripk1	ADJ
bjp-70889	118	18	expression	expression	NOUN
bjp-70889	118	19	(	(	PUNCT
bjp-70889	118	20	p<0.05	p<0.05	NOUN
bjp-70889	118	21	)	)	PUNCT
bjp-70889	118	22	.	.	PUNCT
bjp-70889	119	1	necroptosis	necroptosis	NOUN
bjp-70889	119	2	in	in	ADP
bjp-70889	119	3	h8	h8	PROPN
bjp-70889	119	4	cells	cell	NOUN
bjp-70889	119	5	independent	independent	ADJ
bjp-70889	119	6	of	of	ADP
bjp-70889	119	7	caspase	caspase	PROPN
bjp-70889	119	8	activation	activation	NOUN
bjp-70889	119	9	the	the	DET
bjp-70889	119	10	results	result	NOUN
bjp-70889	119	11	illustrated	illustrate	VERB
bjp-70889	119	12	a	a	DET
bjp-70889	119	13	decrease	decrease	NOUN
bjp-70889	119	14	in	in	ADP
bjp-70889	119	15	the	the	DET
bjp-70889	119	16	expression	expression	NOUN
bjp-70889	119	17	of	of	ADP
bjp-70889	119	18	c	c	NOUN
bjp-70889	119	19	-	-	PUNCT
bjp-70889	119	20	caspase-8	caspase-8	NOUN
bjp-70889	119	21	and	and	CCONJ
bjp-70889	119	22	c	c	AUX
bjp-70889	119	23	-	-	PUNCT
bjp-70889	119	24	caspase-3	caspase-3	X
bjp-70889	119	25	in	in	ADP
bjp-70889	119	26	the	the	DET
bjp-70889	119	27	low	low	ADJ
bjp-70889	119	28	,	,	PUNCT
bjp-70889	119	29	medium	medium	ADJ
bjp-70889	119	30	,	,	PUNCT
bjp-70889	119	31	and	and	CCONJ
bjp-70889	119	32	high	high	ADJ
bjp-70889	119	33	-	-	PUNCT
bjp-70889	119	34	concentration	concentration	NOUN
bjp-70889	119	35	berberine	berberine	NOUN
bjp-70889	119	36	intervention	intervention	NOUN
bjp-70889	119	37	groups	group	NOUN
bjp-70889	119	38	compared	compare	VERB
bjp-70889	119	39	to	to	ADP
bjp-70889	119	40	the	the	DET
bjp-70889	119	41	control	control	NOUN
bjp-70889	119	42	group	group	NOUN
bjp-70889	119	43	(	(	PUNCT
bjp-70889	119	44	figure	figure	NOUN
bjp-70889	119	45	5a	5a	NUM
bjp-70889	119	46	,	,	PUNCT
bjp-70889	119	47	c	c	NOUN
bjp-70889	119	48	-	-	SYM
bjp-70889	119	49	d	d	NOUN
bjp-70889	119	50	;	;	PUNCT
bjp-70889	119	51	p<0.05	p<0.05	PROPN
bjp-70889	119	52	)	)	PUNCT
bjp-70889	119	53	.	.	PUNCT
bjp-70889	120	1	however	however	ADV
bjp-70889	120	2	,	,	PUNCT
bjp-70889	120	3	upon	upon	SCONJ
bjp-70889	120	4	the	the	DET
bjp-70889	120	5	addition	addition	NOUN
bjp-70889	120	6	of	of	ADP
bjp-70889	120	7	the	the	DET
bjp-70889	120	8	nec-1	nec-1	ADJ
bjp-70889	120	9	inhibitor	inhibitor	NOUN
bjp-70889	120	10	(	(	PUNCT
bjp-70889	120	11	figure	figure	NOUN
bjp-70889	120	12	5b	5b	NOUN
bjp-70889	120	13	,	,	PUNCT
bjp-70889	120	14	e	e	NOUN
bjp-70889	120	15	-	-	NOUN
bjp-70889	120	16	f	f	NOUN
bjp-70889	120	17	)	)	PUNCT
bjp-70889	120	18	,	,	PUNCT
bjp-70889	120	19	figure	figure	VERB
bjp-70889	120	20	3：the	3：the	DET
bjp-70889	120	21	mrna	mrna	PROPN
bjp-70889	120	22	expression	expression	NOUN
bjp-70889	120	23	levels	level	NOUN
bjp-70889	120	24	of	of	ADP
bjp-70889	120	25	ripk1	ripk1	NOUN
bjp-70889	120	26	and	and	CCONJ
bjp-70889	120	27	mlkl	mlkl	PROPN
bjp-70889	120	28	in	in	ADP
bjp-70889	120	29	h8	h8	PROPN
bjp-70889	120	30	cells	cell	NOUN
bjp-70889	120	31	were	be	AUX
bjp-70889	120	32	analyzed	analyze	VERB
bjp-70889	120	33	by	by	ADP
bjp-70889	120	34	qrt	qrt	NOUN
bjp-70889	120	35	-pcr	-pcr	X
bjp-70889	120	36	(	(	PUNCT
bjp-70889	120	37	a	a	PROPN
bjp-70889	120	38	-	-	PUNCT
bjp-70889	120	39	b	b	NOUN
bjp-70889	120	40	)	)	PUNCT
bjp-70889	120	41	;	;	PUNCT
bjp-70889	120	42	protein	protein	NOUN
bjp-70889	120	43	electrophoresis	electrophoresis	NOUN
bjp-70889	120	44	of	of	ADP
bjp-70889	120	45	ripk1	ripk1	NOUN
bjp-70889	120	46	,	,	PUNCT
bjp-70889	120	47	mlkl	mlkl	ADJ
bjp-70889	120	48	,	,	PUNCT
bjp-70889	120	49	p	p	NOUN
bjp-70889	120	50	-	-	PUNCT
bjp-70889	120	51	mlkl	mlkl	NOUN
bjp-70889	120	52	in	in	ADP
bjp-70889	120	53	each	each	DET
bjp-70889	120	54	group	group	NOUN
bjp-70889	120	55	(	(	PUNCT
bjp-70889	120	56	c	c	NOUN
bjp-70889	120	57	)	)	PUNCT
bjp-70889	120	58	.	.	PUNCT
bjp-70889	121	1	different	different	ADJ
bjp-70889	121	2	concentration	concentration	NOUN
bjp-70889	121	3	of	of	ADP
bjp-70889	121	4	berberine	berberine	NOUN
bjp-70889	121	5	interferes	interfere	VERB
bjp-70889	121	6	with	with	ADP
bjp-70889	121	7	the	the	DET
bjp-70889	121	8	expression	expression	NOUN
bjp-70889	121	9	level	level	NOUN
bjp-70889	121	10	of	of	ADP
bjp-70889	121	11	ripk1	ripk1	ADJ
bjp-70889	121	12	protein	protein	NOUN
bjp-70889	121	13	in	in	ADP
bjp-70889	121	14	h8	h8	PROPN
bjp-70889	121	15	cells	cell	NOUN
bjp-70889	121	16	(	(	PUNCT
bjp-70889	121	17	d	d	NOUN
bjp-70889	121	18	)	)	PUNCT
bjp-70889	121	19	.	.	PUNCT
bjp-70889	122	1	different	different	ADJ
bjp-70889	122	2	concentrations	concentration	NOUN
bjp-70889	122	3	of	of	ADP
bjp-70889	122	4	berberine	berberine	NOUN
bjp-70889	122	5	interfere	interfere	VERB
bjp-70889	122	6	with	with	ADP
bjp-70889	122	7	p	p	NOUN
bjp-70889	122	8	mlkl	mlkl	VERB
bjp-70889	122	9	/	/	SYM
bjp-70889	122	10	mlkl	mlkl	NOUN
bjp-70889	122	11	protein	protein	NOUN
bjp-70889	122	12	expression	expression	NOUN
bjp-70889	122	13	ratio	ratio	NOUN
bjp-70889	122	14	in	in	ADP
bjp-70889	122	15	h8	h8	PROPN
bjp-70889	122	16	cells	cell	NOUN
bjp-70889	122	17	(	(	PUNCT
bjp-70889	122	18	e	e	NOUN
bjp-70889	122	19	)	)	PUNCT
bjp-70889	122	20	.	.	PUNCT
bjp-70889	123	1	data	datum	NOUN
bjp-70889	123	2	are	be	AUX
bjp-70889	123	3	expressed	express	VERB
bjp-70889	123	4	as	as	ADP
bjp-70889	123	5	mean	mean	PROPN
bjp-70889	123	6	±	±	NUM
bjp-70889	123	7	sem	sem	NOUN
bjp-70889	123	8	.	.	PUNCT
bjp-70889	124	1	compared	compare	VERB
bjp-70889	124	2	to	to	ADP
bjp-70889	124	3	the	the	DET
bjp-70889	124	4	control	control	NOUN
bjp-70889	124	5	group	group	NOUN
bjp-70889	124	6	,	,	PUNCT
bjp-70889	124	7	ap＜0.05	ap＜0.05	PROPN
bjp-70889	124	8	;	;	PUNCT
bjp-70889	124	9	bp＜0.01	bp＜0.01	ADJ
bjp-70889	124	10	berberine	berberine	NOUN
bjp-70889	124	11	(	(	PUNCT
bjp-70889	124	12	µm	µm	NOUN
bjp-70889	124	13	)	)	PUNCT
bjp-70889	124	14	berberine	berberine	NOUN
bjp-70889	124	15	(	(	PUNCT
bjp-70889	124	16	µm	µm	NOUN
bjp-70889	124	17	)	)	PUNCT
bjp-70889	124	18	berberine	berberine	NOUN
bjp-70889	124	19	(	(	PUNCT
bjp-70889	124	20	µm	µm	NOUN
bjp-70889	124	21	)	)	PUNCT
bjp-70889	124	22	berberine	berberine	NOUN
bjp-70889	124	23	(	(	PUNCT
bjp-70889	124	24	µm	µm	NOUN
bjp-70889	124	25	)	)	PUNCT
bjp-70889	124	26	berberine	berberine	NOUN
bjp-70889	124	27	0	0	NUM
bjp-70889	124	28	20	20	NUM
bjp-70889	124	29	40	40	NUM
bjp-70889	124	30	80	80	NUM
bjp-70889	124	31	(	(	PUNCT
bjp-70889	124	32	µm	µm	NOUN
bjp-70889	124	33	)	)	PUNCT
bjp-70889	124	34	a	a	DET
bjp-70889	124	35	b	b	NOUN
bjp-70889	124	36	c	c	NOUN
bjp-70889	124	37	d	d	X
bjp-70889	124	38	e	e	ADP
bjp-70889	124	39	ripk1	ripk1	NOUN
bjp-70889	124	40	mlkl	mlkl	VERB
bjp-70889	124	41	p	p	NOUN
bjp-70889	124	42	-	-	PUNCT
bjp-70889	124	43	mlkl	mlkl	VERB
bjp-70889	124	44	β	β	NOUN
bjp-70889	124	45	-	-	NOUN
bjp-70889	124	46	actin	actin	VERB
bjp-70889	124	47	a	a	DET
bjp-70889	124	48	a	a	DET
bjp-70889	124	49	a	a	DET
bjp-70889	124	50	a	a	DET
bjp-70889	124	51	a	a	DET
bjp-70889	124	52	b	b	PROPN
bjp-70889	124	53	b	b	PROPN
bjp-70889	124	54	b	b	PROPN
bjp-70889	124	55	b	b	PROPN
bjp-70889	124	56	b	b	PROPN
bjp-70889	124	57	b	b	PROPN
bjp-70889	124	58	b	b	PROPN
bjp-70889	124	59	bangladesh	bangladesh	PROPN
bjp-70889	124	60	j	j	PROPN
bjp-70889	124	61	pharmacol	pharmacol	PROPN
bjp-70889	124	62	2024	2024	NUM
bjp-70889	124	63	;	;	PUNCT
bjp-70889	124	64	19	19	NUM
bjp-70889	124	65	:	:	SYM
bjp-70889	124	66	13	13	NUM
bjp-70889	124	67	-	-	SYM
bjp-70889	124	68	22	22	NUM
bjp-70889	124	69	17	17	NUM
bjp-70889	124	70	no	no	DET
bjp-70889	124	71	significant	significant	ADJ
bjp-70889	124	72	changes	change	NOUN
bjp-70889	124	73	in	in	ADP
bjp-70889	124	74	the	the	DET
bjp-70889	124	75	expression	expression	NOUN
bjp-70889	124	76	of	of	ADP
bjp-70889	124	77	c	c	NOUN
bjp-70889	124	78	-	-	PUNCT
bjp-70889	124	79	caspase-8	caspase-8	NOUN
bjp-70889	124	80	and	and	CCONJ
bjp-70889	124	81	c	c	X
bjp-70889	124	82	-	-	PUNCT
bjp-70889	124	83	caspase-3	caspase-3	PROPN
bjp-70889	124	84	were	be	AUX
bjp-70889	124	85	observed	observe	VERB
bjp-70889	124	86	(	(	PUNCT
bjp-70889	124	87	p>0.05	p>0.05	NOUN
bjp-70889	124	88	)	)	PUNCT
bjp-70889	124	89	.	.	PUNCT
bjp-70889	125	1	discussion	discussion	NOUN
bjp-70889	125	2	the	the	DET
bjp-70889	125	3	present	present	ADJ
bjp-70889	125	4	study	study	NOUN
bjp-70889	125	5	shows	show	VERB
bjp-70889	125	6	that	that	SCONJ
bjp-70889	125	7	berberine	berberine	NOUN
bjp-70889	125	8	can	can	AUX
bjp-70889	125	9	inhibit	inhibit	VERB
bjp-70889	125	10	the	the	DET
bjp-70889	125	11	proliferation	proliferation	NOUN
bjp-70889	125	12	of	of	ADP
bjp-70889	125	13	h8	h8	PROPN
bjp-70889	125	14	cells	cell	NOUN
bjp-70889	125	15	by	by	ADP
bjp-70889	125	16	activating	activate	VERB
bjp-70889	125	17	ripk1	ripk1	NOUN
bjp-70889	125	18	,	,	PUNCT
bjp-70889	125	19	and	and	CCONJ
bjp-70889	125	20	the	the	DET
bjp-70889	125	21	underlying	underlying	ADJ
bjp-70889	125	22	mechanism	mechanism	NOUN
bjp-70889	125	23	may	may	AUX
bjp-70889	125	24	be	be	AUX
bjp-70889	125	25	related	relate	VERB
bjp-70889	125	26	to	to	ADP
bjp-70889	125	27	the	the	DET
bjp-70889	125	28	ability	ability	NOUN
bjp-70889	125	29	of	of	ADP
bjp-70889	125	30	berberine	berberine	NOUN
bjp-70889	125	31	to	to	PART
bjp-70889	125	32	activate	activate	VERB
bjp-70889	125	33	ripk1	ripk1	NOUN
bjp-70889	125	34	-	-	PUNCT
bjp-70889	125	35	mediated	mediate	VERB
bjp-70889	125	36	necroptosis	necroptosis	NOUN
bjp-70889	125	37	.	.	PUNCT
bjp-70889	126	1	it	it	PRON
bjp-70889	126	2	has	have	AUX
bjp-70889	126	3	been	be	AUX
bjp-70889	126	4	found	find	VERB
bjp-70889	126	5	that	that	SCONJ
bjp-70889	126	6	youdujing	youduje	VERB
bjp-70889	126	7	(	(	PUNCT
bjp-70889	126	8	a	a	DET
bjp-70889	126	9	traditional	traditional	ADJ
bjp-70889	126	10	chinese	chinese	ADJ
bjp-70889	126	11	herbal	herbal	ADJ
bjp-70889	126	12	formula	formula	NOUN
bjp-70889	126	13	)	)	PUNCT
bjp-70889	126	14	can	can	AUX
bjp-70889	126	15	trigger	trigger	VERB
bjp-70889	126	16	necroptosis	necroptosis	NOUN
bjp-70889	126	17	in	in	ADP
bjp-70889	126	18	ecto	ecto	PROPN
bjp-70889	126	19	-	-	ADJ
bjp-70889	126	20	cervical	cervical	ADJ
bjp-70889	126	21	ect1	ect1	NOUN
bjp-70889	126	22	/	/	SYM
bjp-70889	126	23	e6e7	e6e7	NOUN
bjp-70889	126	24	cells	cell	NOUN
bjp-70889	126	25	by	by	ADP
bjp-70889	126	26	activation	activation	NOUN
bjp-70889	126	27	of	of	ADP
bjp-70889	126	28	ripk1	ripk1	ADJ
bjp-70889	126	29	kinase	kinase	PROPN
bjp-70889	126	30	(	(	PUNCT
bjp-70889	126	31	chen	chen	PROPN
bjp-70889	126	32	et	et	PROPN
bjp-70889	126	33	al	al	PROPN
bjp-70889	126	34	.	.	PROPN
bjp-70889	126	35	,	,	PUNCT
bjp-70889	126	36	2019	2019	NUM
bjp-70889	126	37	)	)	PUNCT
bjp-70889	126	38	.	.	PUNCT
bjp-70889	127	1	it	it	PRON
bjp-70889	127	2	is	be	AUX
bjp-70889	127	3	suggested	suggest	VERB
bjp-70889	127	4	that	that	SCONJ
bjp-70889	127	5	activating	activate	VERB
bjp-70889	127	6	ripk1	ripk1	NOUN
bjp-70889	127	7	to	to	PART
bjp-70889	127	8	induce	induce	VERB
bjp-70889	127	9	the	the	DET
bjp-70889	127	10	necroptosis	necroptosis	NOUN
bjp-70889	127	11	pathway	pathway	NOUN
bjp-70889	127	12	may	may	AUX
bjp-70889	127	13	be	be	AUX
bjp-70889	127	14	a	a	DET
bjp-70889	127	15	new	new	ADJ
bjp-70889	127	16	target	target	NOUN
bjp-70889	127	17	for	for	ADP
bjp-70889	127	18	treating	treat	VERB
bjp-70889	127	19	cervical	cervical	ADJ
bjp-70889	127	20	intraepithelial	intraepithelial	ADJ
bjp-70889	127	21	neoplasia	neoplasia	NOUN
bjp-70889	127	22	.	.	PUNCT
bjp-70889	128	1	berberine	berberine	NOUN
bjp-70889	128	2	induces	induce	VERB
bjp-70889	128	3	necroptosis	necroptosis	NOUN
bjp-70889	128	4	independent	independent	ADJ
bjp-70889	128	5	of	of	ADP
bjp-70889	128	6	caspase	caspase	NOUN
bjp-70889	128	7	activation	activation	NOUN
bjp-70889	128	8	,	,	PUNCT
bjp-70889	128	9	with	with	ADP
bjp-70889	128	10	caspase-3	caspase-3	NUM
bjp-70889	128	11	and	and	CCONJ
bjp-70889	128	12	caspase-8	caspase-8	PRON
bjp-70889	128	13	being	be	AUX
bjp-70889	128	14	maintained	maintain	VERB
bjp-70889	128	15	in	in	ADP
bjp-70889	128	16	an	an	DET
bjp-70889	128	17	inhibited	inhibited	ADJ
bjp-70889	128	18	state	state	NOUN
bjp-70889	128	19	.	.	PUNCT
bjp-70889	129	1	in	in	ADP
bjp-70889	129	2	recent	recent	ADJ
bjp-70889	129	3	years	year	NOUN
bjp-70889	129	4	,	,	PUNCT
bjp-70889	129	5	the	the	DET
bjp-70889	129	6	ongoing	ongoing	ADJ
bjp-70889	129	7	progress	progress	NOUN
bjp-70889	129	8	in	in	ADP
bjp-70889	129	9	cell	cell	NOUN
bjp-70889	129	10	biology	biology	NOUN
bjp-70889	129	11	has	have	AUX
bjp-70889	129	12	unveiled	unveil	VERB
bjp-70889	129	13	necroptosis	necroptosis	NOUN
bjp-70889	129	14	as	as	ADP
bjp-70889	129	15	a	a	DET
bjp-70889	129	16	regulated	regulated	ADJ
bjp-70889	129	17	cell	cell	NOUN
bjp-70889	129	18	death	death	NOUN
bjp-70889	129	19	mechanism	mechanism	NOUN
bjp-70889	129	20	.	.	PUNCT
bjp-70889	130	1	numerous	numerous	ADJ
bjp-70889	130	2	studies	study	NOUN
bjp-70889	130	3	have	have	AUX
bjp-70889	130	4	highlighted	highlight	VERB
bjp-70889	130	5	the	the	DET
bjp-70889	130	6	underexpression	underexpression	NOUN
bjp-70889	130	7	of	of	ADP
bjp-70889	130	8	key	key	ADJ
bjp-70889	130	9	proteins	protein	NOUN
bjp-70889	130	10	within	within	ADP
bjp-70889	130	11	the	the	DET
bjp-70889	130	12	necroptotic	necroptotic	ADJ
bjp-70889	130	13	pathway	pathway	NOUN
bjp-70889	130	14	in	in	ADP
bjp-70889	130	15	specific	specific	ADJ
bjp-70889	130	16	tumors	tumor	NOUN
bjp-70889	130	17	.	.	PUNCT
bjp-70889	131	1	for	for	ADP
bjp-70889	131	2	instance	instance	NOUN
bjp-70889	131	3	,	,	PUNCT
bjp-70889	131	4	ripk3	ripk3	NOUN
bjp-70889	131	5	has	have	AUX
bjp-70889	131	6	been	be	AUX
bjp-70889	131	7	identified	identify	VERB
bjp-70889	131	8	figure	figure	NOUN
bjp-70889	131	9	4：the	4：the	PROPN
bjp-70889	131	10	cck-8	cck-8	PUNCT
bjp-70889	131	11	assay	assay	PROPN
bjp-70889	131	12	was	be	AUX
bjp-70889	131	13	unviability	unviability	NOUN
bjp-70889	131	14	after	after	ADP
bjp-70889	131	15	berberine	berberine	NOUN
bjp-70889	131	16	(	(	PUNCT
bjp-70889	131	17	40	40	NUM
bjp-70889	131	18	µm	µm	NOUN
bjp-70889	131	19	)	)	PUNCT
bjp-70889	131	20	and/or	and/or	CCONJ
bjp-70889	131	21	nec-1	nec-1	X
bjp-70889	131	22	(	(	PUNCT
bjp-70889	131	23	2.5	2.5	NUM
bjp-70889	131	24	µm	µm	NOUN
bjp-70889	131	25	)	)	PUNCT
bjp-70889	131	26	intervention	intervention	NOUN
bjp-70889	131	27	(	(	PUNCT
bjp-70889	131	28	a	a	NOUN
bjp-70889	131	29	)	)	PUNCT
bjp-70889	131	30	.	.	PUNCT
bjp-70889	132	1	the	the	DET
bjp-70889	132	2	expression	expression	NOUN
bjp-70889	132	3	levels	level	NOUN
bjp-70889	132	4	of	of	ADP
bjp-70889	132	5	ripk1	ripk1	NOUN
bjp-70889	132	6	and	and	CCONJ
bjp-70889	132	7	mlkl	mlkl	PROPN
bjp-70889	132	8	mrna	mrna	PROPN
bjp-70889	132	9	after	after	ADP
bjp-70889	132	10	berberine	berberine	NOUN
bjp-70889	132	11	and/or	and/or	CCONJ
bjp-70889	132	12	nec-1	nec-1	ADP
bjp-70889	132	13	intervention	intervention	NOUN
bjp-70889	132	14	were	be	AUX
bjp-70889	132	15	detected	detect	VERB
bjp-70889	132	16	by	by	ADP
bjp-70889	132	17	q	q	NOUN
bjp-70889	132	18	-	-	PUNCT
bjp-70889	132	19	rtpcr	rtpcr	ADJ
bjp-70889	132	20	(	(	PUNCT
bjp-70889	132	21	b	b	X
bjp-70889	132	22	-	-	PUNCT
bjp-70889	132	23	c	c	NOUN
bjp-70889	132	24	)	)	PUNCT
bjp-70889	132	25	.	.	PUNCT
bjp-70889	133	1	the	the	DET
bjp-70889	133	2	expression	expression	NOUN
bjp-70889	133	3	levels	level	NOUN
bjp-70889	133	4	of	of	ADP
bjp-70889	133	5	ripk1	ripk1	ADJ
bjp-70889	133	6	protein	protein	NOUN
bjp-70889	133	7	and	and	CCONJ
bjp-70889	133	8	p	p	NOUN
bjp-70889	133	9	-	-	PUNCT
bjp-70889	133	10	mlkl	mlkl	VERB
bjp-70889	133	11	/	/	SYM
bjp-70889	133	12	mlkl	mlkl	NOUN
bjp-70889	133	13	protein	protein	NOUN
bjp-70889	133	14	expression	expression	NOUN
bjp-70889	133	15	ratio	ratio	NOUN
bjp-70889	133	16	of	of	ADP
bjp-70889	133	17	berberine	berberine	NOUN
bjp-70889	133	18	(	(	PUNCT
bjp-70889	133	19	40	40	NUM
bjp-70889	133	20	µm	µm	NOUN
bjp-70889	133	21	)	)	PUNCT
bjp-70889	133	22	and/or	and/or	CCONJ
bjp-70889	133	23	nec-1	nec-1	X
bjp-70889	133	24	(	(	PUNCT
bjp-70889	133	25	2.5	2.5	NUM
bjp-70889	133	26	µm	µm	NOUN
bjp-70889	133	27	)	)	PUNCT
bjp-70889	133	28	in	in	ADP
bjp-70889	133	29	h8	h8	PROPN
bjp-70889	133	30	cells	cell	NOUN
bjp-70889	133	31	were	be	AUX
bjp-70889	133	32	detected	detect	VERB
bjp-70889	133	33	by	by	ADP
bjp-70889	133	34	western	western	ADJ
bjp-70889	133	35	blot	blot	NOUN
bjp-70889	133	36	(	(	PUNCT
bjp-70889	133	37	d	d	NOUN
bjp-70889	133	38	-	-	PUNCT
bjp-70889	133	39	f	f	NOUN
bjp-70889	133	40	)	)	PUNCT
bjp-70889	133	41	.	.	PUNCT
bjp-70889	134	1	the	the	DET
bjp-70889	134	2	expression	expression	NOUN
bjp-70889	134	3	levels	level	NOUN
bjp-70889	134	4	of	of	ADP
bjp-70889	134	5	ripk1	ripk1	NOUN
bjp-70889	134	6	in	in	ADP
bjp-70889	134	7	h8	h8	PROPN
bjp-70889	134	8	cells	cell	NOUN
bjp-70889	134	9	treated	treat	VERB
bjp-70889	134	10	with	with	ADP
bjp-70889	134	11	berberine	berberine	NOUN
bjp-70889	134	12	(	(	PUNCT
bjp-70889	134	13	40	40	NUM
bjp-70889	134	14	µm	µm	NOUN
bjp-70889	134	15	)	)	PUNCT
bjp-70889	134	16	and/or	and/or	CCONJ
bjp-70889	134	17	nec-1	nec-1	X
bjp-70889	134	18	(	(	PUNCT
bjp-70889	134	19	2.5	2.5	NUM
bjp-70889	134	20	µm	µm	NOUN
bjp-70889	134	21	)	)	PUNCT
bjp-70889	134	22	were	be	AUX
bjp-70889	134	23	detected	detect	VERB
bjp-70889	134	24	by	by	ADP
bjp-70889	134	25	immunofluorescence	immunofluorescence	NOUN
bjp-70889	134	26	sed	se	VERB
bjp-70889	134	27	to	to	PART
bjp-70889	134	28	detect	detect	VERB
bjp-70889	134	29	h8	h8	PROPN
bjp-70889	134	30	cells	cell	NOUN
bjp-70889	134	31	(	(	PUNCT
bjp-70889	134	32	g	g	NOUN
bjp-70889	134	33	-	-	PUNCT
bjp-70889	134	34	h	h	NOUN
bjp-70889	134	35	)	)	PUNCT
bjp-70889	134	36	.	.	PUNCT
bjp-70889	135	1	data	datum	NOUN
bjp-70889	135	2	are	be	AUX
bjp-70889	135	3	expressed	express	VERB
bjp-70889	135	4	as	as	ADP
bjp-70889	135	5	mean	mean	PROPN
bjp-70889	135	6	±	±	NUM
bjp-70889	135	7	sem	sem	NOUN
bjp-70889	135	8	;	;	PUNCT
bjp-70889	135	9	ap＜0.05，bp＜0.01	ap＜0.05，bp＜0.01	PROPN
bjp-70889	135	10	.	.	PUNCT
bjp-70889	136	1	a	a	DET
bjp-70889	136	2	b	b	X
bjp-70889	136	3	c	c	NOUN
bjp-70889	136	4	d	d	X
bjp-70889	136	5	f	f	PROPN
bjp-70889	136	6	e	e	PROPN
bjp-70889	136	7	g	g	PROPN
bjp-70889	136	8	h	h	PROPN
bjp-70889	136	9	berberine	berberine	NOUN
bjp-70889	136	10	+	+	X
bjp-70889	136	11	+	+	PUNCT
bjp-70889	136	12	nec-1	nec-1	PRON
bjp-70889	136	13	+	+	NOUN
bjp-70889	136	14	+	+	NUM
bjp-70889	136	15	berberine	berberine	NOUN
bjp-70889	136	16	+	+	X
bjp-70889	136	17	+	+	PUNCT
bjp-70889	136	18	nec-1	nec-1	PRON
bjp-70889	136	19	+	+	NOUN
bjp-70889	136	20	+	+	NUM
bjp-70889	136	21	berberine	berberine	NOUN
bjp-70889	136	22	+	+	X
bjp-70889	136	23	+	+	PUNCT
bjp-70889	136	24	nec-1	nec-1	PRON
bjp-70889	136	25	+	+	NOUN
bjp-70889	136	26	+	+	NUM
bjp-70889	136	27	berberine	berberine	NOUN
bjp-70889	136	28	+	+	X
bjp-70889	136	29	+	+	PUNCT
bjp-70889	136	30	nec-1	nec-1	PRON
bjp-70889	136	31	+	+	NOUN
bjp-70889	136	32	+	+	NUM
bjp-70889	136	33	berberine	berberine	NOUN
bjp-70889	136	34	+	+	X
bjp-70889	136	35	+	+	PUNCT
bjp-70889	136	36	nec-1	nec-1	PRON
bjp-70889	136	37	+	+	NOUN
bjp-70889	136	38	+	+	NUM
bjp-70889	136	39	berberine	berberine	NOUN
bjp-70889	136	40	+	+	X
bjp-70889	136	41	+	+	PUNCT
bjp-70889	136	42	nec-1	nec-1	PRON
bjp-70889	136	43	+	+	NOUN
bjp-70889	136	44	+	+	NUM
bjp-70889	136	45	berberine	berberine	NOUN
bjp-70889	136	46	+	+	X
bjp-70889	136	47	+	+	PUNCT
bjp-70889	136	48	nec-1	nec-1	PRON
bjp-70889	136	49	+	+	NOUN
bjp-70889	136	50	+	+	NUM
bjp-70889	136	51	berberine	berberine	NOUN
bjp-70889	136	52	+	+	X
bjp-70889	136	53	+	+	PUNCT
bjp-70889	136	54	nec-1	nec-1	X
bjp-70889	136	55	+	+	NOUN
bjp-70889	136	56	+	+	CCONJ
bjp-70889	136	57	a	a	DET
bjp-70889	136	58	b	b	NOUN
bjp-70889	136	59	a	a	DET
bjp-70889	136	60	a	a	DET
bjp-70889	136	61	b	b	PROPN
bjp-70889	136	62	b	b	PROPN
bjp-70889	136	63	b	b	PROPN
bjp-70889	136	64	b	b	PROPN
bjp-70889	136	65	b	b	PROPN
bjp-70889	136	66	b	b	PROPN
bjp-70889	136	67	b	b	PROPN
bjp-70889	136	68	b	b	PROPN
bjp-70889	136	69	18	18	NUM
bjp-70889	136	70	bangladesh	bangladesh	NOUN
bjp-70889	136	71	j	j	PROPN
bjp-70889	136	72	pharmacol	pharmacol	PROPN
bjp-70889	136	73	2024	2024	NUM
bjp-70889	136	74	;	;	PUNCT
bjp-70889	136	75	19	19	NUM
bjp-70889	136	76	:	:	SYM
bjp-70889	136	77	13	13	NUM
bjp-70889	136	78	-	-	SYM
bjp-70889	136	79	22	22	NUM
bjp-70889	136	80	as	as	SCONJ
bjp-70889	136	81	under	under	ADV
bjp-70889	136	82	-	-	PUNCT
bjp-70889	136	83	expressed	express	VERB
bjp-70889	136	84	in	in	ADP
bjp-70889	136	85	primary	primary	ADJ
bjp-70889	136	86	colorectal	colorectal	ADJ
bjp-70889	136	87	cancer	cancer	NOUN
bjp-70889	136	88	(	(	PUNCT
bjp-70889	136	89	feng	feng	PROPN
bjp-70889	136	90	et	et	PROPN
bjp-70889	136	91	al	al	PROPN
bjp-70889	136	92	.	.	PROPN
bjp-70889	136	93	,	,	PUNCT
bjp-70889	136	94	2015	2015	NUM
bjp-70889	136	95	)	)	PUNCT
bjp-70889	136	96	.	.	PUNCT
bjp-70889	137	1	additionally	additionally	ADV
bjp-70889	137	2	,	,	PUNCT
bjp-70889	137	3	the	the	DET
bjp-70889	137	4	under	under	NOUN
bjp-70889	137	5	-	-	PUNCT
bjp-70889	137	6	expression	expression	NOUN
bjp-70889	137	7	of	of	ADP
bjp-70889	137	8	mlkl	mlkl	PROPN
bjp-70889	137	9	has	have	AUX
bjp-70889	137	10	been	be	AUX
bjp-70889	137	11	linked	link	VERB
bjp-70889	137	12	to	to	ADP
bjp-70889	137	13	unfavorable	unfavorable	ADJ
bjp-70889	137	14	prognosis	prognosis	NOUN
bjp-70889	137	15	in	in	ADP
bjp-70889	137	16	patients	patient	NOUN
bjp-70889	137	17	with	with	ADP
bjp-70889	137	18	various	various	ADJ
bjp-70889	137	19	malignant	malignant	ADJ
bjp-70889	137	20	tumors	tumor	NOUN
bjp-70889	137	21	,	,	PUNCT
bjp-70889	137	22	including	include	VERB
bjp-70889	137	23	ovarian	ovarian	ADJ
bjp-70889	137	24	cancer	cancer	NOUN
bjp-70889	137	25	,	,	PUNCT
bjp-70889	137	26	cervical	cervical	ADJ
bjp-70889	137	27	squamous	squamous	ADJ
bjp-70889	137	28	cell	cell	NOUN
bjp-70889	137	29	carcinoma	carcinoma	NOUN
bjp-70889	137	30	,	,	PUNCT
bjp-70889	137	31	gastric	gastric	ADJ
bjp-70889	137	32	cancer	cancer	NOUN
bjp-70889	137	33	,	,	PUNCT
bjp-70889	137	34	and	and	CCONJ
bjp-70889	137	35	colorectal	colorectal	ADJ
bjp-70889	137	36	cancer	cancer	NOUN
bjp-70889	137	37	(	(	PUNCT
bjp-70889	137	38	park	park	NOUN
bjp-70889	137	39	et	et	PROPN
bjp-70889	137	40	al	al	PROPN
bjp-70889	137	41	.	.	PROPN
bjp-70889	137	42	,	,	PUNCT
bjp-70889	137	43	2020	2020	NUM
bjp-70889	137	44	;	;	PUNCT
bjp-70889	137	45	ruan	ruan	PROPN
bjp-70889	137	46	et	et	PROPN
bjp-70889	137	47	al	al	PROPN
bjp-70889	137	48	.	.	PROPN
bjp-70889	137	49	,	,	PUNCT
bjp-70889	137	50	2015	2015	NUM
bjp-70889	137	51	;	;	PUNCT
bjp-70889	137	52	sun	sun	PROPN
bjp-70889	137	53	et	et	PROPN
bjp-70889	137	54	al	al	PROPN
bjp-70889	137	55	.	.	PROPN
bjp-70889	137	56	,	,	PUNCT
bjp-70889	137	57	2019	2019	NUM
bjp-70889	137	58	)	)	PUNCT
bjp-70889	137	59	.	.	PUNCT
bjp-70889	138	1	in	in	ADP
bjp-70889	138	2	the	the	DET
bjp-70889	138	3	development	development	NOUN
bjp-70889	138	4	and	and	CCONJ
bjp-70889	138	5	progression	progression	NOUN
bjp-70889	138	6	of	of	ADP
bjp-70889	138	7	specific	specific	ADJ
bjp-70889	138	8	tumors	tumor	NOUN
bjp-70889	138	9	,	,	PUNCT
bjp-70889	138	10	the	the	DET
bjp-70889	138	11	inhibition	inhibition	NOUN
bjp-70889	138	12	of	of	ADP
bjp-70889	138	13	necroptosis	necroptosis	NOUN
bjp-70889	138	14	might	might	AUX
bjp-70889	138	15	contribute	contribute	VERB
bjp-70889	138	16	to	to	ADP
bjp-70889	138	17	the	the	DET
bjp-70889	138	18	malignant	malignant	ADJ
bjp-70889	138	19	proliferation	proliferation	NOUN
bjp-70889	138	20	of	of	ADP
bjp-70889	138	21	tumor	tumor	NOUN
bjp-70889	138	22	cells	cell	NOUN
bjp-70889	138	23	.	.	PUNCT
bjp-70889	139	1	unlike	unlike	ADP
bjp-70889	139	2	apoptosis	apoptosis	NOUN
bjp-70889	139	3	,	,	PUNCT
bjp-70889	139	4	which	which	PRON
bjp-70889	139	5	relies	rely	VERB
bjp-70889	139	6	on	on	ADP
bjp-70889	139	7	the	the	DET
bjp-70889	139	8	caspase	caspase	NOUN
bjp-70889	139	9	-	-	PUNCT
bjp-70889	139	10	dependent	dependent	ADJ
bjp-70889	139	11	pathway	pathway	NOUN
bjp-70889	139	12	,	,	PUNCT
bjp-70889	139	13	necroptosis	necroptosis	NOUN
bjp-70889	139	14	operates	operate	VERB
bjp-70889	139	15	through	through	ADP
bjp-70889	139	16	a	a	DET
bjp-70889	139	17	caspase	caspase	NOUN
bjp-70889	139	18	-	-	PUNCT
bjp-70889	139	19	independent	independent	ADJ
bjp-70889	139	20	pathway	pathway	NOUN
bjp-70889	139	21	.	.	PUNCT
bjp-70889	140	1	activating	activate	VERB
bjp-70889	140	2	necroptosis	necroptosis	NOUN
bjp-70889	140	3	in	in	ADP
bjp-70889	140	4	the	the	DET
bjp-70889	140	5	presence	presence	NOUN
bjp-70889	140	6	of	of	ADP
bjp-70889	140	7	caspase	caspase	NOUN
bjp-70889	140	8	inhibitors	inhibitor	NOUN
bjp-70889	140	9	can	can	AUX
bjp-70889	140	10	serve	serve	VERB
bjp-70889	140	11	as	as	ADP
bjp-70889	140	12	a	a	DET
bjp-70889	140	13	mechanism	mechanism	NOUN
bjp-70889	140	14	for	for	ADP
bjp-70889	140	15	inducing	induce	VERB
bjp-70889	140	16	suicide	suicide	NOUN
bjp-70889	140	17	in	in	ADP
bjp-70889	140	18	tumor	tumor	NOUN
bjp-70889	140	19	cells	cell	NOUN
bjp-70889	140	20	,	,	PUNCT
bjp-70889	140	21	thereby	thereby	ADV
bjp-70889	140	22	limiting	limit	VERB
bjp-70889	140	23	their	their	PRON
bjp-70889	140	24	proli	proli	NOUN
bjp-70889	140	25	feration	feration	NOUN
bjp-70889	140	26	(	(	PUNCT
bjp-70889	140	27	chen	chen	PROPN
bjp-70889	140	28	et	et	PROPN
bjp-70889	140	29	al	al	PROPN
bjp-70889	140	30	.	.	PROPN
bjp-70889	140	31	,	,	PUNCT
bjp-70889	140	32	2019	2019	NUM
bjp-70889	140	33	;	;	PUNCT
bjp-70889	140	34	park	park	NOUN
bjp-70889	140	35	et	et	PROPN
bjp-70889	140	36	al	al	PROPN
bjp-70889	140	37	.	.	PROPN
bjp-70889	140	38	,	,	PUNCT
bjp-70889	140	39	2020	2020	NUM
bjp-70889	140	40	)	)	PUNCT
bjp-70889	140	41	.	.	PUNCT
bjp-70889	141	1	when	when	SCONJ
bjp-70889	141	2	human	human	ADJ
bjp-70889	141	3	papillomavirus	papillomavirus	NOUN
bjp-70889	141	4	infects	infect	VERB
bjp-70889	141	5	host	host	NOUN
bjp-70889	141	6	cells	cell	NOUN
bjp-70889	141	7	,	,	PUNCT
bjp-70889	141	8	the	the	DET
bjp-70889	141	9	release	release	NOUN
bjp-70889	141	10	of	of	ADP
bjp-70889	141	11	intracellular	intracellular	ADJ
bjp-70889	141	12	immune	immune	ADJ
bjp-70889	141	13	stimulatory	stimulatory	ADJ
bjp-70889	141	14	components	component	NOUN
bjp-70889	141	15	promotes	promote	VERB
bjp-70889	141	16	host	host	NOUN
bjp-70889	141	17	innate	innate	ADJ
bjp-70889	141	18	immune	immune	ADJ
bjp-70889	141	19	responses	response	NOUN
bjp-70889	141	20	,	,	PUNCT
bjp-70889	141	21	forming	form	VERB
bjp-70889	141	22	a	a	DET
bjp-70889	141	23	potent	potent	ADJ
bjp-70889	141	24	antiviral	antiviral	ADJ
bjp-70889	141	25	defense	defense	NOUN
bjp-70889	141	26	mechanism	mechanism	NOUN
bjp-70889	141	27	by	by	ADP
bjp-70889	141	28	inducing	induce	VERB
bjp-70889	141	29	host	host	NOUN
bjp-70889	141	30	cell	cell	NOUN
bjp-70889	141	31	death	death	NOUN
bjp-70889	141	32	early	early	ADV
bjp-70889	141	33	to	to	PART
bjp-70889	141	34	disrupt	disrupt	VERB
bjp-70889	141	35	the	the	DET
bjp-70889	141	36	viral	viral	ADJ
bjp-70889	141	37	replication	replication	NOUN
bjp-70889	141	38	ecosystem	ecosystem	NOUN
bjp-70889	141	39	(	(	PUNCT
bjp-70889	141	40	vanden	vanden	PROPN
bjp-70889	141	41	et	et	PROPN
bjp-70889	141	42	al	al	PROPN
bjp-70889	141	43	.	.	PROPN
bjp-70889	141	44	,	,	PUNCT
bjp-70889	141	45	2014	2014	NUM
bjp-70889	141	46	;	;	PUNCT
bjp-70889	141	47	warowicka	warowicka	PROPN
bjp-70889	141	48	et	et	PROPN
bjp-70889	141	49	al	al	PROPN
bjp-70889	141	50	.	.	PROPN
bjp-70889	141	51	,	,	PUNCT
bjp-70889	141	52	2020	2020	NUM
bjp-70889	141	53	)	)	PUNCT
bjp-70889	141	54	.	.	PUNCT
bjp-70889	142	1	it	it	PRON
bjp-70889	142	2	has	have	AUX
bjp-70889	142	3	been	be	AUX
bjp-70889	142	4	identified	identify	VERB
bjp-70889	142	5	that	that	SCONJ
bjp-70889	142	6	large	large	ADJ
bjp-70889	142	7	dna	dna	PROPN
bjp-70889	142	8	viruses	virus	NOUN
bjp-70889	142	9	are	be	AUX
bjp-70889	142	10	capable	capable	ADJ
bjp-70889	142	11	of	of	ADP
bjp-70889	142	12	inhibiting	inhibit	VERB
bjp-70889	142	13	apoptosis	apoptosis	NOUN
bjp-70889	142	14	by	by	ADP
bjp-70889	142	15	blocking	block	VERB
bjp-70889	142	16	the	the	DET
bjp-70889	142	17	activity	activity	NOUN
bjp-70889	142	18	of	of	ADP
bjp-70889	142	19	the	the	DET
bjp-70889	142	20	extrinsic	extrinsic	ADJ
bjp-70889	142	21	apoptotic	apoptotic	ADJ
bjp-70889	142	22	initiator	initiator	NOUN
bjp-70889	142	23	caspase-8	caspase-8	PROPN
bjp-70889	142	24	,	,	PUNCT
bjp-70889	142	25	which	which	PRON
bjp-70889	142	26	,	,	PUNCT
bjp-70889	142	27	in	in	ADP
bjp-70889	142	28	turn	turn	NOUN
bjp-70889	142	29	,	,	PUNCT
bjp-70889	142	30	can	can	AUX
bjp-70889	142	31	suppress	suppress	VERB
bjp-70889	142	32	necroptosis	necroptosis	NOUN
bjp-70889	142	33	by	by	ADP
bjp-70889	142	34	cleaving	cleave	VERB
bjp-70889	142	35	ripk1	ripk1	NOUN
bjp-70889	142	36	and	and	CCONJ
bjp-70889	142	37	ripk3	ripk3	NOUN
bjp-70889	142	38	(	(	PUNCT
bjp-70889	142	39	verdonck	verdonck	NOUN
bjp-70889	142	40	et	et	PROPN
bjp-70889	142	41	al	al	PROPN
bjp-70889	142	42	.	.	PROPN
bjp-70889	142	43	,	,	PUNCT
bjp-70889	142	44	2022	2022	NUM
bjp-70889	142	45	)	)	PUNCT
bjp-70889	142	46	.	.	PUNCT
bjp-70889	143	1	thus	thus	ADV
bjp-70889	143	2	,	,	PUNCT
bjp-70889	143	3	when	when	SCONJ
bjp-70889	143	4	the	the	DET
bjp-70889	143	5	virus	virus	NOUN
bjp-70889	143	6	inhibits	inhibit	VERB
bjp-70889	143	7	caspase-8	caspase-8	PROPN
bjp-70889	143	8	,	,	PUNCT
bjp-70889	143	9	necrosomes	necrosome	NOUN
bjp-70889	143	10	can	can	AUX
bjp-70889	143	11	be	be	AUX
bjp-70889	143	12	recruited	recruit	VERB
bjp-70889	143	13	at	at	ADP
bjp-70889	143	14	the	the	DET
bjp-70889	143	15	tnfr1	tnfr1	PROPN
bjp-70889	143	16	(	(	PUNCT
bjp-70889	143	17	tnf	tnf	PROPN
bjp-70889	143	18	receptor	receptor	NOUN
bjp-70889	143	19	1	1	NUM
bjp-70889	143	20	)	)	PUNCT
bjp-70889	143	21	stimulus	stimulus	NOUN
bjp-70889	143	22	to	to	PART
bjp-70889	143	23	counteract	counteract	VERB
bjp-70889	143	24	viral	viral	ADJ
bjp-70889	143	25	infection	infection	NOUN
bjp-70889	143	26	.	.	PUNCT
bjp-70889	144	1	other	other	ADJ
bjp-70889	144	2	relevant	relevant	ADJ
bjp-70889	144	3	studies	study	NOUN
bjp-70889	144	4	have	have	AUX
bjp-70889	144	5	also	also	ADV
bjp-70889	144	6	suggested	suggest	VERB
bjp-70889	144	7	that	that	SCONJ
bjp-70889	144	8	necroptosis	necroptosis	NOUN
bjp-70889	144	9	may	may	AUX
bjp-70889	144	10	not	not	PART
bjp-70889	144	11	only	only	ADV
bjp-70889	144	12	occur	occur	VERB
bjp-70889	144	13	when	when	SCONJ
bjp-70889	144	14	caspase-8	caspase-8	NOUN
bjp-70889	144	15	activity	activity	NOUN
bjp-70889	144	16	is	be	AUX
bjp-70889	144	17	blocked	block	VERB
bjp-70889	144	18	but	but	CCONJ
bjp-70889	144	19	can	can	AUX
bjp-70889	144	20	also	also	ADV
bjp-70889	144	21	act	act	VERB
bjp-70889	144	22	as	as	ADP
bjp-70889	144	23	an	an	DET
bjp-70889	144	24	independent	independent	ADJ
bjp-70889	144	25	mechanism	mechanism	NOUN
bjp-70889	144	26	to	to	PART
bjp-70889	144	27	inhibit	inhibit	VERB
bjp-70889	144	28	viral	viral	ADJ
bjp-70889	144	29	infection	infection	NOUN
bjp-70889	144	30	(	(	PUNCT
bjp-70889	144	31	bertheloot	bertheloot	PROPN
bjp-70889	144	32	et	et	PROPN
bjp-70889	144	33	al	al	PROPN
bjp-70889	144	34	.	.	PROPN
bjp-70889	144	35	,	,	PUNCT
bjp-70889	144	36	2021	2021	NUM
bjp-70889	144	37	)	)	PUNCT
bjp-70889	144	38	.	.	PUNCT
bjp-70889	145	1	berberine，a	berberine，a	NOUN
bjp-70889	145	2	natural	natural	ADJ
bjp-70889	145	3	alkaloid	alkaloid	PROPN
bjp-70889	145	4	compound	compound	NOUN
bjp-70889	145	5	found	find	VERB
bjp-70889	145	6	in	in	ADP
bjp-70889	145	7	various	various	ADJ
bjp-70889	145	8	plants	plant	NOUN
bjp-70889	145	9	,	,	PUNCT
bjp-70889	145	10	including	include	VERB
bjp-70889	145	11	coptis	coptis	ADJ
bjp-70889	145	12	chinensis	chinensis	NOUN
bjp-70889	145	13	and	and	CCONJ
bjp-70889	145	14	p	p	NOUN
bjp-70889	145	15	h	h	NOUN
bjp-70889	145	16	e	e	NOUN
bjp-70889	145	17	l	l	NOUN
bjp-70889	145	18	l	l	NOUN
bjp-70889	146	1	o	o	X
bjp-70889	146	2	d	d	X
bjp-70889	146	3	en	en	X
bjp-70889	146	4	d	d	PROPN
bjp-70889	146	5	ro	ro	X
bjp-70889	146	6	n	n	ADV
bjp-70889	146	7	,	,	PUNCT
bjp-70889	146	8	no	no	DET
bjp-70889	146	9	t	t	NOUN
bjp-70889	146	10	o	o	NOUN
bjp-70889	146	11	n	n	CCONJ
bjp-70889	146	12	l	l	NOUN
bjp-70889	146	13	y	y	NOUN
bjp-70889	146	14	e	e	X
bjp-70889	146	15	xh	xh	PROPN
bjp-70889	147	1	i	i	PRON
bjp-70889	147	2	b	b	VERB
bjp-70889	148	1	i	i	PRON
bjp-70889	148	2	t	t	X
bjp-70889	148	3	s	s	VERB
bjp-70889	148	4	a	a	PRON
bjp-70889	148	5	n	n	CCONJ
bjp-70889	148	6	antiproliferative	antiproliferative	ADJ
bjp-70889	148	7	effect	effect	NOUN
bjp-70889	148	8	on	on	ADP
bjp-70889	148	9	cancer	cancer	NOUN
bjp-70889	148	10	cells	cell	NOUN
bjp-70889	148	11	but	but	CCONJ
bjp-70889	148	12	also	also	ADV
bjp-70889	148	13	demonstrates	demonstrate	VERB
bjp-70889	148	14	the	the	DET
bjp-70889	148	15	capability	capability	NOUN
bjp-70889	148	16	to	to	PART
bjp-70889	148	17	target	target	VERB
bjp-70889	148	18	different	different	ADJ
bjp-70889	148	19	stages	stage	NOUN
bjp-70889	148	20	of	of	ADP
bjp-70889	148	21	the	the	DET
bjp-70889	148	22	virus	virus	NOUN
bjp-70889	148	23	life	life	NOUN
bjp-70889	148	24	cycle	cycle	NOUN
bjp-70889	148	25	,	,	PUNCT
bjp-70889	148	26	activate	activate	VERB
bjp-70889	148	27	immune	immune	ADJ
bjp-70889	148	28	cells	cell	NOUN
bjp-70889	148	29	,	,	PUNCT
bjp-70889	148	30	and	and	CCONJ
bjp-70889	148	31	exert	exert	VERB
bjp-70889	148	32	an	an	DET
bjp-70889	148	33	antiviral	antiviral	ADJ
bjp-70889	148	34	effect	effect	NOUN
bjp-70889	148	35	(	(	PUNCT
bjp-70889	148	36	liu	liu	PROPN
bjp-70889	148	37	et	et	PROPN
bjp-70889	148	38	al	al	PROPN
bjp-70889	148	39	.	.	PROPN
bjp-70889	148	40	,	,	PUNCT
bjp-70889	148	41	2019	2019	NUM
bjp-70889	148	42	;	;	PUNCT
bjp-70889	149	1	kim	kim	PROPN
bjp-70889	149	2	et	et	PROPN
bjp-70889	149	3	al	al	PROPN
bjp-70889	149	4	.	.	PROPN
bjp-70889	149	5	,	,	PUNCT
bjp-70889	149	6	2016	2016	NUM
bjp-70889	149	7	;	;	PUNCT
bjp-70889	149	8	warowicka	warowicka	PROPN
bjp-70889	149	9	et	et	PROPN
bjp-70889	149	10	al	al	PROPN
bjp-70889	149	11	.	.	PROPN
bjp-70889	149	12	,	,	PUNCT
bjp-70889	149	13	2020	2020	NUM
bjp-70889	149	14	)	)	PUNCT
bjp-70889	149	15	.	.	PUNCT
bjp-70889	150	1	importantly	importantly	ADV
bjp-70889	150	2	,	,	PUNCT
bjp-70889	150	3	berberine	berberine	NOUN
bjp-70889	150	4	has	have	AUX
bjp-70889	150	5	shown	show	VERB
bjp-70889	150	6	relative	relative	ADJ
bjp-70889	150	7	safety	safety	NOUN
bjp-70889	150	8	for	for	ADP
bjp-70889	150	9	normal	normal	ADJ
bjp-70889	150	10	cells	cell	NOUN
bjp-70889	150	11	.	.	PUNCT
bjp-70889	151	1	a	a	DET
bjp-70889	151	2	study	study	NOUN
bjp-70889	151	3	has	have	AUX
bjp-70889	151	4	been	be	AUX
bjp-70889	151	5	conducted	conduct	VERB
bjp-70889	151	6	to	to	PART
bjp-70889	151	7	investigate	investigate	VERB
bjp-70889	151	8	the	the	DET
bjp-70889	151	9	cytotoxic	cytotoxic	ADJ
bjp-70889	151	10	effects	effect	NOUN
bjp-70889	151	11	of	of	ADP
bjp-70889	151	12	berberine	berberine	NOUN
bjp-70889	151	13	on	on	ADP
bjp-70889	151	14	normal	normal	ADJ
bjp-70889	151	15	human	human	ADJ
bjp-70889	151	16	prostate	prostate	NOUN
bjp-70889	151	17	epithelial	epithelial	ADJ
bjp-70889	151	18	cells	cell	NOUN
bjp-70889	151	19	(	(	PUNCT
bjp-70889	151	20	mantena	mantena	PROPN
bjp-70889	151	21	et	et	PROPN
bjp-70889	151	22	al	al	PROPN
bjp-70889	151	23	.	.	PROPN
bjp-70889	151	24	,	,	PUNCT
bjp-70889	151	25	2006	2006	NUM
bjp-70889	151	26	)	)	PUNCT
bjp-70889	151	27	.	.	PUNCT
bjp-70889	152	1	their	their	PRON
bjp-70889	152	2	results	result	NOUN
bjp-70889	152	3	indicated	indicate	VERB
bjp-70889	152	4	that	that	SCONJ
bjp-70889	152	5	berberine	berberine	NOUN
bjp-70889	152	6	concentrations	concentration	NOUN
bjp-70889	152	7	ranging	range	VERB
bjp-70889	152	8	from	from	ADP
bjp-70889	152	9	10	10	NUM
bjp-70889	152	10	to	to	PART
bjp-70889	152	11	100	100	NUM
bjp-70889	152	12	μm	μm	NOUN
bjp-70889	152	13	did	do	AUX
bjp-70889	152	14	not	not	PART
bjp-70889	152	15	exhibit	exhibit	VERB
bjp-70889	152	16	significant	significant	ADJ
bjp-70889	152	17	toxicity	toxicity	NOUN
bjp-70889	152	18	on	on	ADP
bjp-70889	152	19	normal	normal	ADJ
bjp-70889	152	20	prostate	prostate	NOUN
bjp-70889	152	21	cells	cell	NOUN
bjp-70889	152	22	,	,	PUNCT
bjp-70889	152	23	suggesting	suggest	VERB
bjp-70889	152	24	that	that	SCONJ
bjp-70889	152	25	the	the	DET
bjp-70889	152	26	intervention	intervention	NOUN
bjp-70889	152	27	concentra	concentra	PROPN
bjp-70889	152	28	tions	tion	NOUN
bjp-70889	152	29	used	use	VERB
bjp-70889	152	30	in	in	ADP
bjp-70889	152	31	this	this	DET
bjp-70889	152	32	study	study	NOUN
bjp-70889	152	33	fall	fall	VERB
bjp-70889	152	34	within	within	ADP
bjp-70889	152	35	safe	safe	ADJ
bjp-70889	152	36	limits	limit	NOUN
bjp-70889	152	37	.	.	PUNCT
bjp-70889	153	1	this	this	DET
bjp-70889	153	2	study	study	NOUN
bjp-70889	153	3	delved	delve	VERB
bjp-70889	153	4	into	into	ADP
bjp-70889	153	5	the	the	DET
bjp-70889	153	6	mechanism	mechanism	NOUN
bjp-70889	153	7	of	of	ADP
bjp-70889	153	8	action	action	NOUN
bjp-70889	153	9	of	of	ADP
bjp-70889	153	10	berberine	berberine	NOUN
bjp-70889	153	11	on	on	ADP
bjp-70889	153	12	cervical	cervical	ADJ
bjp-70889	153	13	h8	h8	PROPN
bjp-70889	153	14	cells	cell	NOUN
bjp-70889	153	15	,	,	PUNCT
bjp-70889	153	16	revealing	reveal	VERB
bjp-70889	153	17	its	its	PRON
bjp-70889	153	18	ability	ability	NOUN
bjp-70889	153	19	to	to	PART
bjp-70889	153	20	inhibit	inhibit	VERB
bjp-70889	153	21	h8	h8	PROPN
bjp-70889	153	22	cell	cell	NOUN
bjp-70889	153	23	proliferation	proliferation	NOUN
bjp-70889	153	24	in	in	ADP
bjp-70889	153	25	a	a	DET
bjp-70889	153	26	timedependent	timedependent	NOUN
bjp-70889	153	27	and	and	CCONJ
bjp-70889	153	28	dose	dose	NOUN
bjp-70889	153	29	-	-	PUNCT
bjp-70889	153	30	dependent	dependent	ADJ
bjp-70889	153	31	manner	manner	NOUN
bjp-70889	153	32	.	.	PUNCT
bjp-70889	154	1	notably	notably	ADV
bjp-70889	154	2	,	,	PUNCT
bjp-70889	154	3	berberine	berberine	NOUN
bjp-70889	154	4	induces	induce	VERB
bjp-70889	154	5	necroptosis	necroptosis	NOUN
bjp-70889	154	6	in	in	ADP
bjp-70889	154	7	cervical	cervical	ADJ
bjp-70889	154	8	h8	h8	NOUN
bjp-70889	154	9	cells	cell	NOUN
bjp-70889	154	10	by	by	ADP
bjp-70889	154	11	activating	activate	VERB
bjp-70889	154	12	ripk1	ripk1	NOUN
bjp-70889	154	13	.	.	PUNCT
bjp-70889	155	1	these	these	DET
bjp-70889	155	2	findings	finding	NOUN
bjp-70889	155	3	offer	offer	VERB
bjp-70889	155	4	valuable	valuable	ADJ
bjp-70889	155	5	insights	insight	NOUN
bjp-70889	155	6	into	into	ADP
bjp-70889	155	7	the	the	DET
bjp-70889	155	8	potential	potential	ADJ
bjp-70889	155	9	therapeutic	therapeutic	ADJ
bjp-70889	155	10	effects	effect	NOUN
bjp-70889	155	11	of	of	ADP
bjp-70889	155	12	berberine	berberine	NOUN
bjp-70889	155	13	,	,	PUNCT
bjp-70889	155	14	specifically	specifically	ADV
bjp-70889	155	15	in	in	ADP
bjp-70889	155	16	targeting	target	VERB
bjp-70889	155	17	necroptosis	necroptosis	NOUN
bjp-70889	155	18	for	for	ADP
bjp-70889	155	19	the	the	DET
bjp-70889	155	20	treatment	treatment	NOUN
bjp-70889	155	21	of	of	ADP
bjp-70889	155	22	cervical	cervical	ADJ
bjp-70889	155	23	intraepi	intraepi	PROPN
bjp-70889	155	24	thelial	thelial	PROPN
bjp-70889	155	25	neoplasia	neoplasia	NOUN
bjp-70889	155	26	.	.	PUNCT
bjp-70889	156	1	figure	figure	VERB
bjp-70889	156	2	5：protein	5：protein	NUM
bjp-70889	156	3	electrophoresis	electrophoresis	NOUN
bjp-70889	156	4	of	of	ADP
bjp-70889	156	5	c	c	PROPN
bjp-70889	156	6	-caspase-8	-caspase-8	PROPN
bjp-70889	156	7	and	and	CCONJ
bjp-70889	156	8	c	c	AUX
bjp-70889	156	9	-	-	PUNCT
bjp-70889	156	10	caspase-3	caspase-3	X
bjp-70889	156	11	in	in	ADP
bjp-70889	156	12	each	each	DET
bjp-70889	156	13	group	group	NOUN
bjp-70889	156	14	(	(	PUNCT
bjp-70889	156	15	a	a	PROPN
bjp-70889	156	16	-	-	PUNCT
bjp-70889	156	17	b	b	NOUN
bjp-70889	156	18	)	)	PUNCT
bjp-70889	156	19	.	.	PUNCT
bjp-70889	157	1	western	western	ADJ
bjp-70889	157	2	blot	blot	NOUN
bjp-70889	157	3	assay	assay	NOUN
bjp-70889	157	4	was	be	AUX
bjp-70889	157	5	used	use	VERB
bjp-70889	157	6	to	to	PART
bjp-70889	157	7	detect	detect	VERB
bjp-70889	157	8	the	the	DET
bjp-70889	157	9	expression	expression	NOUN
bjp-70889	157	10	levels	level	NOUN
bjp-70889	157	11	of	of	ADP
bjp-70889	157	12	c	c	NOUN
bjp-70889	157	13	-	-	PUNCT
bjp-70889	157	14	caspase-8	caspase-8	NOUN
bjp-70889	157	15	and	and	CCONJ
bjp-70889	157	16	c	c	NOUN
bjp-70889	157	17	-	-	PUNCT
bjp-70889	157	18	caspase-3	caspase-3	PUNCT
bjp-70889	157	19	protein	protein	NOUN
bjp-70889	157	20	after	after	ADP
bjp-70889	157	21	intervention	intervention	NOUN
bjp-70889	157	22	with	with	ADP
bjp-70889	157	23	different	different	ADJ
bjp-70889	157	24	concentrations	concentration	NOUN
bjp-70889	157	25	of	of	ADP
bjp-70889	157	26	berberine	berberine	NOUN
bjp-70889	157	27	in	in	ADP
bjp-70889	157	28	h8	h8	PROPN
bjp-70889	157	29	cells	cell	NOUN
bjp-70889	157	30	(	(	PUNCT
bjp-70889	157	31	c	c	NOUN
bjp-70889	157	32	-	-	PUNCT
bjp-70889	157	33	d	d	NOUN
bjp-70889	157	34	)	)	PUNCT
bjp-70889	157	35	.	.	PUNCT
bjp-70889	158	1	western	western	ADJ
bjp-70889	158	2	blot	blot	NOUN
bjp-70889	158	3	assay	assay	NOUN
bjp-70889	158	4	was	be	AUX
bjp-70889	158	5	used	use	VERB
bjp-70889	158	6	to	to	PART
bjp-70889	158	7	detect	detect	VERB
bjp-70889	158	8	the	the	DET
bjp-70889	158	9	expression	expression	NOUN
bjp-70889	158	10	levels	level	NOUN
bjp-70889	158	11	of	of	ADP
bjp-70889	158	12	c	c	NOUN
bjp-70889	158	13	caspase-8	caspase-8	PROPN
bjp-70889	158	14	and	and	CCONJ
bjp-70889	158	15	c	c	NOUN
bjp-70889	158	16	-	-	PUNCT
bjp-70889	158	17	caspase-3	caspase-3	PUNCT
bjp-70889	158	18	protein	protein	NOUN
bjp-70889	158	19	after	after	ADP
bjp-70889	158	20	berberine	berberine	NOUN
bjp-70889	158	21	(	(	PUNCT
bjp-70889	158	22	40	40	NUM
bjp-70889	158	23	µm	µm	NOUN
bjp-70889	158	24	)	)	PUNCT
bjp-70889	158	25	and/or	and/or	CCONJ
bjp-70889	158	26	nec-1	nec-1	X
bjp-70889	158	27	(	(	PUNCT
bjp-70889	158	28	2.5	2.5	NUM
bjp-70889	158	29	µm	µm	NOUN
bjp-70889	158	30	)	)	PUNCT
bjp-70889	158	31	intervention	intervention	NOUN
bjp-70889	158	32	in	in	ADP
bjp-70889	158	33	h8	h8	PROPN
bjp-70889	158	34	cells	cell	NOUN
bjp-70889	158	35	(	(	PUNCT
bjp-70889	158	36	e	e	NOUN
bjp-70889	158	37	-	-	NOUN
bjp-70889	158	38	f	f	NOUN
bjp-70889	158	39	)	)	PUNCT
bjp-70889	158	40	.	.	PUNCT
bjp-70889	159	1	data	datum	NOUN
bjp-70889	159	2	are	be	AUX
bjp-70889	159	3	expressed	express	VERB
bjp-70889	159	4	as	as	ADP
bjp-70889	159	5	mean	mean	PROPN
bjp-70889	159	6	±	±	NUM
bjp-70889	159	7	sem	sem	NOUN
bjp-70889	159	8	.	.	PUNCT
bjp-70889	160	1	compared	compare	VERB
bjp-70889	160	2	to	to	ADP
bjp-70889	160	3	the	the	DET
bjp-70889	160	4	control	control	NOUN
bjp-70889	160	5	group	group	NOUN
bjp-70889	160	6	,	,	PUNCT
bjp-70889	160	7	ap＜0.05，bp＜0.01	ap＜0.05，bp＜0.01	VERB
bjp-70889	160	8	a	a	DET
bjp-70889	160	9	c	c	NOUN
bjp-70889	160	10	d	d	X
bjp-70889	160	11	b	b	PROPN
bjp-70889	160	12	e	e	X
bjp-70889	160	13	f	f	PROPN
bjp-70889	160	14	berberine	berberine	NOUN
bjp-70889	160	15	+	+	X
bjp-70889	160	16	+	+	PUNCT
bjp-70889	160	17	nec-1	nec-1	PRON
bjp-70889	160	18	+	+	NOUN
bjp-70889	160	19	+	+	NUM
bjp-70889	160	20	berberine	berberine	NOUN
bjp-70889	160	21	+	+	X
bjp-70889	160	22	+	+	PUNCT
bjp-70889	160	23	nec-1	nec-1	PRON
bjp-70889	160	24	+	+	NOUN
bjp-70889	160	25	+	+	NUM
bjp-70889	160	26	berberine	berberine	NOUN
bjp-70889	160	27	+	+	X
bjp-70889	160	28	+	+	PUNCT
bjp-70889	160	29	nec-1	nec-1	PRON
bjp-70889	160	30	+	+	CCONJ
bjp-70889	160	31	+	+	NUM
bjp-70889	160	32	berberine	berberine	NOUN
bjp-70889	160	33	(	(	PUNCT
bjp-70889	160	34	µm	µm	NOUN
bjp-70889	160	35	)	)	PUNCT
bjp-70889	160	36	berberine	berberine	NOUN
bjp-70889	160	37	(	(	PUNCT
bjp-70889	160	38	µm	µm	NOUN
bjp-70889	160	39	)	)	PUNCT
bjp-70889	160	40	berberine	berberine	NOUN
bjp-70889	160	41	0	0	NUM
bjp-70889	160	42	20	20	NUM
bjp-70889	160	43	40	40	NUM
bjp-70889	160	44	80	80	NUM
bjp-70889	160	45	(	(	PUNCT
bjp-70889	160	46	µm	µm	NOUN
bjp-70889	160	47	)	)	PUNCT
bjp-70889	160	48	a	a	DET
bjp-70889	160	49	b	b	NOUN
bjp-70889	160	50	a	a	DET
bjp-70889	160	51	b	b	PROPN
bjp-70889	160	52	b	b	PROPN
bjp-70889	160	53	b	b	PROPN
bjp-70889	160	54	b	b	PROPN
bjp-70889	160	55	b	b	PROPN
bjp-70889	160	56	bangladesh	bangladesh	PROPN
bjp-70889	160	57	j	j	PROPN
bjp-70889	160	58	pharmacol	pharmacol	PROPN
bjp-70889	160	59	2024	2024	NUM
bjp-70889	160	60	;	;	PUNCT
bjp-70889	160	61	19	19	NUM
bjp-70889	160	62	:	:	SYM
bjp-70889	160	63	13	13	NUM
bjp-70889	160	64	-	-	SYM
bjp-70889	160	65	22	22	NUM
bjp-70889	160	66	19	19	NUM
bjp-70889	160	67	the	the	DET
bjp-70889	160	68	results	result	NOUN
bjp-70889	160	69	revealed	reveal	VERB
bjp-70889	160	70	a	a	DET
bjp-70889	160	71	significant	significant	ADJ
bjp-70889	160	72	inhibition	inhibition	NOUN
bjp-70889	160	73	of	of	ADP
bjp-70889	160	74	h8	h8	PROPN
bjp-70889	160	75	cell	cell	NOUN
bjp-70889	160	76	growth	growth	NOUN
bjp-70889	160	77	by	by	ADP
bjp-70889	160	78	berberine	berberine	NOUN
bjp-70889	160	79	(	(	PUNCT
bjp-70889	160	80	p<0.05	p<0.05	PROPN
bjp-70889	160	81	)	)	PUNCT
bjp-70889	160	82	,	,	PUNCT
bjp-70889	160	83	indicating	indicate	VERB
bjp-70889	160	84	its	its	PRON
bjp-70889	160	85	potential	potential	NOUN
bjp-70889	160	86	to	to	PART
bjp-70889	160	87	suppress	suppress	VERB
bjp-70889	160	88	cell	cell	NOUN
bjp-70889	160	89	proliferation	proliferation	NOUN
bjp-70889	160	90	through	through	ADP
bjp-70889	160	91	the	the	DET
bjp-70889	160	92	necroptotic	necroptotic	ADJ
bjp-70889	160	93	pathway	pathway	NOUN
bjp-70889	160	94	.	.	PUNCT
bjp-70889	161	1	furthermore	furthermore	ADV
bjp-70889	161	2	,	,	PUNCT
bjp-70889	161	3	berberine	berberine	NOUN
bjp-70889	161	4	was	be	AUX
bjp-70889	161	5	found	find	VERB
bjp-70889	161	6	to	to	PART
bjp-70889	161	7	upregulate	upregulate	VERB
bjp-70889	161	8	the	the	DET
bjp-70889	161	9	expression	expression	NOUN
bjp-70889	161	10	levels	level	NOUN
bjp-70889	161	11	of	of	ADP
bjp-70889	161	12	key	key	ADJ
bjp-70889	161	13	necroptosis	necroptosis	NOUN
bjp-70889	161	14	markers	marker	NOUN
bjp-70889	161	15	,	,	PUNCT
bjp-70889	161	16	ripk1	ripk1	NOUN
bjp-70889	161	17	and	and	CCONJ
bjp-70889	161	18	mlkl	mlkl	PROPN
bjp-70889	161	19	(	(	PUNCT
bjp-70889	161	20	p<0.05	p<0.05	NOUN
bjp-70889	161	21	)	)	PUNCT
bjp-70889	161	22	,	,	PUNCT
bjp-70889	161	23	suggesting	suggest	VERB
bjp-70889	161	24	its	its	PRON
bjp-70889	161	25	involvement	involvement	NOUN
bjp-70889	161	26	in	in	ADP
bjp-70889	161	27	activating	activate	VERB
bjp-70889	161	28	the	the	DET
bjp-70889	161	29	necroptotic	necroptotic	ADJ
bjp-70889	161	30	pathway	pathway	NOUN
bjp-70889	161	31	through	through	ADP
bjp-70889	161	32	the	the	DET
bjp-70889	161	33	activation	activation	NOUN
bjp-70889	161	34	of	of	ADP
bjp-70889	161	35	ripk1	ripk1	PROPN
bjp-70889	161	36	kinase	kinase	PROPN
bjp-70889	161	37	.	.	PUNCT
bjp-70889	162	1	the	the	DET
bjp-70889	162	2	initiation	initiation	NOUN
bjp-70889	162	3	of	of	ADP
bjp-70889	162	4	necroptosis	necroptosis	NOUN
bjp-70889	162	5	involves	involve	VERB
bjp-70889	162	6	key	key	ADJ
bjp-70889	162	7	signaling	signaling	ADJ
bjp-70889	162	8	events	event	NOUN
bjp-70889	162	9	,	,	PUNCT
bjp-70889	162	10	including	include	VERB
bjp-70889	162	11	the	the	DET
bjp-70889	162	12	activation	activation	NOUN
bjp-70889	162	13	of	of	ADP
bjp-70889	162	14	ripk1	ripk1	NOUN
bjp-70889	162	15	,	,	PUNCT
bjp-70889	162	16	subsequent	subsequent	ADJ
bjp-70889	162	17	interaction	interaction	NOUN
bjp-70889	162	18	between	between	ADP
bjp-70889	162	19	ripk1	ripk1	NOUN
bjp-70889	162	20	and	and	CCONJ
bjp-70889	162	21	ripk3	ripk3	NOUN
bjp-70889	162	22	,	,	PUNCT
bjp-70889	162	23	and	and	CCONJ
bjp-70889	162	24	eventual	eventual	ADJ
bjp-70889	162	25	mlkl	mlkl	PROPN
bjp-70889	162	26	phosphorylation	phosphorylation	NOUN
bjp-70889	162	27	.	.	PUNCT
bjp-70889	163	1	upon	upon	SCONJ
bjp-70889	163	2	phosphorylation	phosphorylation	NOUN
bjp-70889	163	3	,	,	PUNCT
bjp-70889	163	4	mlkl	mlkl	PROPN
bjp-70889	163	5	oligomerizes	oligomerize	NOUN
bjp-70889	163	6	and	and	CCONJ
bjp-70889	163	7	translocates	translocate	NOUN
bjp-70889	163	8	to	to	ADP
bjp-70889	163	9	the	the	DET
bjp-70889	163	10	cell	cell	NOUN
bjp-70889	163	11	membrane	membrane	NOUN
bjp-70889	163	12	,	,	PUNCT
bjp-70889	163	13	disrupting	disrupt	VERB
bjp-70889	163	14	cell	cell	NOUN
bjp-70889	163	15	integrity	integrity	NOUN
bjp-70889	163	16	,	,	PUNCT
bjp-70889	163	17	forming	form	VERB
bjp-70889	163	18	pores	pore	NOUN
bjp-70889	163	19	,	,	PUNCT
bjp-70889	163	20	and	and	CCONJ
bjp-70889	163	21	releasing	release	VERB
bjp-70889	163	22	damage	damage	NOUN
bjp-70889	163	23	-	-	PUNCT
bjp-70889	163	24	associated	associate	VERB
bjp-70889	163	25	molecular	molecular	ADJ
bjp-70889	163	26	pattern	pattern	NOUN
bjp-70889	163	27	molecules	molecule	NOUN
bjp-70889	163	28	(	(	PUNCT
bjp-70889	163	29	damps	damps	VERB
bjp-70889	163	30	)	)	PUNCT
bjp-70889	163	31	and	and	CCONJ
bjp-70889	163	32	inflammatory	inflammatory	ADJ
bjp-70889	163	33	cytokines	cytokine	NOUN
bjp-70889	163	34	.	.	PUNCT
bjp-70889	164	1	this	this	PRON
bjp-70889	164	2	triggers	trigger	VERB
bjp-70889	164	3	an	an	DET
bjp-70889	164	4	immune	immune	ADJ
bjp-70889	164	5	response	response	NOUN
bjp-70889	164	6	,	,	PUNCT
bjp-70889	164	7	actively	actively	ADV
bjp-70889	164	8	participating	participate	VERB
bjp-70889	164	9	in	in	ADP
bjp-70889	164	10	the	the	DET
bjp-70889	164	11	anti	anti	ADJ
bjp-70889	164	12	-	-	ADJ
bjp-70889	164	13	tumor	tumor	ADJ
bjp-70889	164	14	process	process	NOUN
bjp-70889	164	15	(	(	PUNCT
bjp-70889	164	16	zhang	zhang	X
bjp-70889	164	17	et	et	PROPN
bjp-70889	164	18	al	al	PROPN
bjp-70889	164	19	.	.	PROPN
bjp-70889	164	20	,	,	PUNCT
bjp-70889	164	21	2022	2022	NUM
bjp-70889	164	22	)	)	PUNCT
bjp-70889	164	23	.	.	PUNCT
bjp-70889	165	1	there	there	PRON
bjp-70889	165	2	results	result	VERB
bjp-70889	165	3	,	,	PUNCT
bjp-70889	165	4	further	far	ADV
bjp-70889	165	5	demonstrated	demonstrate	VERB
bjp-70889	165	6	a	a	DET
bjp-70889	165	7	decrease	decrease	NOUN
bjp-70889	165	8	in	in	ADP
bjp-70889	165	9	the	the	DET
bjp-70889	165	10	expression	expression	NOUN
bjp-70889	165	11	of	of	ADP
bjp-70889	165	12	ccaspase-8	ccaspase-8	NUM
bjp-70889	165	13	and	and	CCONJ
bjp-70889	165	14	c	c	NOUN
bjp-70889	165	15	-	-	PUNCT
bjp-70889	165	16	caspase-3	caspase-3	X
bjp-70889	165	17	in	in	ADP
bjp-70889	165	18	the	the	DET
bjp-70889	165	19	berberine	berberine	NOUN
bjp-70889	165	20	-	-	PUNCT
bjp-70889	165	21	treated	treat	VERB
bjp-70889	165	22	group	group	NOUN
bjp-70889	165	23	compared	compare	VERB
bjp-70889	165	24	to	to	ADP
bjp-70889	165	25	the	the	DET
bjp-70889	165	26	control	control	NOUN
bjp-70889	165	27	group(p<0.05	group(p<0.05	PROPN
bjp-70889	165	28	)	)	PUNCT
bjp-70889	165	29	,	,	PUNCT
bjp-70889	165	30	suggesting	suggest	VERB
bjp-70889	165	31	that	that	SCONJ
bjp-70889	165	32	caspase-8	caspase-8	PROPN
bjp-70889	165	33	and	and	CCONJ
bjp-70889	165	34	caspase-3	caspase-3	PRON
bjp-70889	165	35	may	may	AUX
bjp-70889	165	36	be	be	AUX
bjp-70889	165	37	suppressed	suppress	VERB
bjp-70889	165	38	during	during	ADP
bjp-70889	165	39	this	this	DET
bjp-70889	165	40	process	process	NOUN
bjp-70889	165	41	.	.	PUNCT
bjp-70889	166	1	caspase-8	caspase-8	NOUN
bjp-70889	166	2	plays	play	VERB
bjp-70889	166	3	a	a	DET
bjp-70889	166	4	crucial	crucial	ADJ
bjp-70889	166	5	role	role	NOUN
bjp-70889	166	6	in	in	ADP
bjp-70889	166	7	regulating	regulate	VERB
bjp-70889	166	8	cell	cell	NOUN
bjp-70889	166	9	death	death	NOUN
bjp-70889	166	10	pathways	pathway	NOUN
bjp-70889	166	11	,	,	PUNCT
bjp-70889	166	12	activating	activate	VERB
bjp-70889	166	13	apoptosis	apoptosis	NOUN
bjp-70889	166	14	,	,	PUNCT
bjp-70889	166	15	and	and	CCONJ
bjp-70889	166	16	inhibiting	inhibit	VERB
bjp-70889	166	17	necroptosis	necroptosis	NOUN
bjp-70889	166	18	upon	upon	SCONJ
bjp-70889	166	19	activation	activation	NOUN
bjp-70889	166	20	.	.	PUNCT
bjp-70889	167	1	activated	activate	VERB
bjp-70889	167	2	caspase-8	caspase-8	PRON
bjp-70889	167	3	can	can	AUX
bjp-70889	167	4	cleave	cleave	VERB
bjp-70889	167	5	and	and	CCONJ
bjp-70889	167	6	inactivate	inactivate	VERB
bjp-70889	167	7	key	key	ADJ
bjp-70889	167	8	necroptosis	necroptosis	NOUN
bjp-70889	167	9	-	-	PUNCT
bjp-70889	167	10	related	relate	VERB
bjp-70889	167	11	proteins	protein	NOUN
bjp-70889	167	12	such	such	ADJ
bjp-70889	167	13	as	as	ADP
bjp-70889	167	14	ripk1	ripk1	NOUN
bjp-70889	167	15	,	,	PUNCT
bjp-70889	167	16	ripk3	ripk3	NOUN
bjp-70889	167	17	,	,	PUNCT
bjp-70889	167	18	and	and	CCONJ
bjp-70889	167	19	cylindromatosis	cylindromatosis	NOUN
bjp-70889	167	20	(	(	PUNCT
bjp-70889	167	21	cyld	cyld	NOUN
bjp-70889	167	22	)	)	PUNCT
bjp-70889	167	23	,	,	PUNCT
bjp-70889	167	24	leading	lead	VERB
bjp-70889	167	25	to	to	ADP
bjp-70889	167	26	the	the	DET
bjp-70889	167	27	suppression	suppression	NOUN
bjp-70889	167	28	of	of	ADP
bjp-70889	167	29	necroptosis	necroptosis	NOUN
bjp-70889	167	30	and	and	CCONJ
bjp-70889	167	31	the	the	DET
bjp-70889	167	32	activation	activation	NOUN
bjp-70889	167	33	of	of	ADP
bjp-70889	167	34	caspase-3	caspase-3	NUM
bjp-70889	167	35	to	to	PART
bjp-70889	167	36	trigger	trigger	NOUN
bjp-70889	167	37	apoptosis	apoptosis	NOUN
bjp-70889	167	38	.	.	PUNCT
bjp-70889	168	1	inhibition	inhibition	NOUN
bjp-70889	168	2	of	of	ADP
bjp-70889	168	3	caspase-8	caspase-8	NOUN
bjp-70889	168	4	has	have	AUX
bjp-70889	168	5	been	be	AUX
bjp-70889	168	6	shown	show	VERB
bjp-70889	168	7	to	to	PART
bjp-70889	168	8	result	result	VERB
bjp-70889	168	9	in	in	ADP
bjp-70889	168	10	the	the	DET
bjp-70889	168	11	deubiquitination	deubiquitination	NOUN
bjp-70889	168	12	of	of	ADP
bjp-70889	168	13	ripk1	ripk1	NOUN
bjp-70889	168	14	by	by	ADP
bjp-70889	168	15	cyld	cyld	NOUN
bjp-70889	168	16	,	,	PUNCT
bjp-70889	168	17	promoting	promote	VERB
bjp-70889	168	18	kinase	kinase	NOUN
bjp-70889	168	19	activation	activation	NOUN
bjp-70889	168	20	and	and	CCONJ
bjp-70889	168	21	modulating	modulate	VERB
bjp-70889	168	22	necroptosis	necroptosis	NOUN
bjp-70889	168	23	(	(	PUNCT
bjp-70889	168	24	gao	gao	PROPN
bjp-70889	168	25	et	et	PROPN
bjp-70889	168	26	al	al	PROPN
bjp-70889	168	27	.	.	PROPN
bjp-70889	168	28	,	,	PUNCT
bjp-70889	168	29	2022	2022	NUM
bjp-70889	168	30	;	;	PUNCT
bjp-70889	168	31	vanden	vanden	PROPN
bjp-70889	168	32	et	et	PROPN
bjp-70889	168	33	al	al	PROPN
bjp-70889	168	34	.	.	PROPN
bjp-70889	168	35	,	,	PUNCT
bjp-70889	168	36	2014	2014	NUM
bjp-70889	168	37	)	)	PUNCT
bjp-70889	168	38	.	.	PUNCT
bjp-70889	169	1	when	when	SCONJ
bjp-70889	169	2	h8	h8	PROPN
bjp-70889	169	3	cells	cell	NOUN
bjp-70889	169	4	undergo	undergo	VERB
bjp-70889	169	5	necroptosis	necroptosis	NOUN
bjp-70889	169	6	,	,	PUNCT
bjp-70889	169	7	caspase-8	caspase-8	PROPN
bjp-70889	169	8	and	and	CCONJ
bjp-70889	169	9	caspase-3	caspase-3	NUM
bjp-70889	169	10	are	be	AUX
bjp-70889	169	11	in	in	ADP
bjp-70889	169	12	a	a	DET
bjp-70889	169	13	suppressed	suppressed	ADJ
bjp-70889	169	14	state	state	NOUN
bjp-70889	169	15	,	,	PUNCT
bjp-70889	169	16	suggesting	suggest	VERB
bjp-70889	169	17	a	a	DET
bjp-70889	169	18	potential	potential	ADJ
bjp-70889	169	19	mechanism	mechanism	NOUN
bjp-70889	169	20	of	of	ADP
bjp-70889	169	21	mutual	mutual	ADJ
bjp-70889	169	22	transformation	transformation	NOUN
bjp-70889	169	23	between	between	ADP
bjp-70889	169	24	apoptosis	apoptosis	NOUN
bjp-70889	169	25	and	and	CCONJ
bjp-70889	169	26	necroptosis	necroptosis	NOUN
bjp-70889	169	27	in	in	ADP
bjp-70889	169	28	cells	cell	NOUN
bjp-70889	169	29	.	.	PUNCT
bjp-70889	170	1	the	the	DET
bjp-70889	170	2	interchangeability	interchangeability	NOUN
bjp-70889	170	3	of	of	ADP
bjp-70889	170	4	apoptosis	apoptosis	NOUN
bjp-70889	170	5	and	and	CCONJ
bjp-70889	170	6	necroptosis	necroptosis	NOUN
bjp-70889	170	7	has	have	AUX
bjp-70889	170	8	been	be	AUX
bjp-70889	170	9	demonstrated	demonstrate	VERB
bjp-70889	170	10	under	under	ADP
bjp-70889	170	11	certain	certain	ADJ
bjp-70889	170	12	conditions	condition	NOUN
bjp-70889	170	13	in	in	ADP
bjp-70889	170	14	l929	l929	PROPN
bjp-70889	170	15	mouse	mouse	NOUN
bjp-70889	170	16	fibrosarcoma	fibrosarcoma	ADJ
bjp-70889	170	17	cells	cell	NOUN
bjp-70889	170	18	(	(	PUNCT
bjp-70889	170	19	sawai	sawai	PROPN
bjp-70889	170	20	,	,	PUNCT
bjp-70889	170	21	2016	2016	NUM
bjp-70889	170	22	)	)	PUNCT
bjp-70889	170	23	.	.	PUNCT
bjp-70889	171	1	necroptosis	necroptosis	NOUN
bjp-70889	171	2	inhibition	inhibition	NOUN
bjp-70889	171	3	by	by	ADP
bjp-70889	171	4	nec-1	nec-1	ADV
bjp-70889	171	5	led	lead	VERB
bjp-70889	171	6	to	to	ADP
bjp-70889	171	7	the	the	DET
bjp-70889	171	8	activation	activation	NOUN
bjp-70889	171	9	of	of	ADP
bjp-70889	171	10	apoptotic	apoptotic	ADJ
bjp-70889	171	11	pathways	pathway	NOUN
bjp-70889	171	12	and	and	CCONJ
bjp-70889	171	13	subsequent	subsequent	ADJ
bjp-70889	171	14	cell	cell	NOUN
bjp-70889	171	15	death	death	NOUN
bjp-70889	171	16	.	.	PUNCT
bjp-70889	172	1	additionally	additionally	ADV
bjp-70889	172	2	,	,	PUNCT
bjp-70889	172	3	jie	jie	PROPN
bjp-70889	172	4	et	et	PROPN
bjp-70889	172	5	al	al	PROPN
bjp-70889	172	6	.	.	PUNCT
bjp-70889	173	1	(	(	PUNCT
bjp-70889	173	2	jie	jie	PROPN
bjp-70889	173	3	et	et	PROPN
bjp-70889	173	4	al	al	PROPN
bjp-70889	173	5	.	.	PROPN
bjp-70889	173	6	,	,	PUNCT
bjp-70889	173	7	2016	2016	NUM
bjp-70889	173	8	)	)	PUNCT
bjp-70889	173	9	reported	report	VERB
bjp-70889	173	10	that	that	SCONJ
bjp-70889	173	11	nec-1	nec-1	ADP
bjp-70889	173	12	induced	induced	ADJ
bjp-70889	173	13	apoptosis	apoptosis	NOUN
bjp-70889	173	14	in	in	ADP
bjp-70889	173	15	neutrophils	neutrophil	NOUN
bjp-70889	173	16	.	.	PUNCT
bjp-70889	174	1	recent	recent	ADJ
bjp-70889	174	2	studies	study	NOUN
bjp-70889	174	3	indicate	indicate	VERB
bjp-70889	174	4	a	a	DET
bjp-70889	174	5	link	link	NOUN
bjp-70889	174	6	between	between	ADP
bjp-70889	174	7	necroptosis	necroptosis	NOUN
bjp-70889	174	8	and	and	CCONJ
bjp-70889	174	9	tumor	tumor	NOUN
bjp-70889	174	10	immunity	immunity	NOUN
bjp-70889	174	11	,	,	PUNCT
bjp-70889	174	12	emphasizing	emphasize	VERB
bjp-70889	174	13	the	the	DET
bjp-70889	174	14	distinct	distinct	ADJ
bjp-70889	174	15	nature	nature	NOUN
bjp-70889	174	16	of	of	ADP
bjp-70889	174	17	necroptosis	necroptosis	NOUN
bjp-70889	174	18	compared	compare	VERB
bjp-70889	174	19	to	to	ADP
bjp-70889	174	20	traditional	traditional	ADJ
bjp-70889	174	21	apoptosis	apoptosis	NOUN
bjp-70889	174	22	.	.	PUNCT
bjp-70889	174	23	necroptosis	necroptosis	NOUN
bjp-70889	174	24	can	can	AUX
bjp-70889	174	25	elicit	elicit	VERB
bjp-70889	174	26	an	an	DET
bjp-70889	174	27	infla	infla	NOUN
bjp-70889	174	28	mmatory	mmatory	ADJ
bjp-70889	174	29	response	response	NOUN
bjp-70889	174	30	within	within	ADP
bjp-70889	174	31	cells	cell	NOUN
bjp-70889	174	32	by	by	ADP
bjp-70889	174	33	releasing	release	VERB
bjp-70889	174	34	damage	damage	NOUN
bjp-70889	174	35	-	-	PUNCT
bjp-70889	174	36	associated	associate	VERB
bjp-70889	174	37	molecular	molecular	ADJ
bjp-70889	174	38	patterns	pattern	NOUN
bjp-70889	174	39	(	(	PUNCT
bjp-70889	174	40	damps	damps	PROPN
bjp-70889	174	41	)	)	PUNCT
bjp-70889	174	42	,	,	PUNCT
bjp-70889	174	43	leading	lead	VERB
bjp-70889	174	44	to	to	ADP
bjp-70889	174	45	immune	immune	ADJ
bjp-70889	174	46	system	system	NOUN
bjp-70889	174	47	activation―a	activation―a	PROPN
bjp-70889	174	48	pheno	pheno	PROPN
bjp-70889	174	49	menon	menon	PROPN
bjp-70889	174	50	often	often	ADV
bjp-70889	174	51	termed	term	VERB
bjp-70889	174	52	necrotic	necrotic	ADJ
bjp-70889	174	53	inflammation	inflammation	NOUN
bjp-70889	174	54	(	(	PUNCT
bjp-70889	174	55	bertheloot	bertheloot	PROPN
bjp-70889	174	56	et	et	PROPN
bjp-70889	174	57	al	al	PROPN
bjp-70889	174	58	.	.	PROPN
bjp-70889	174	59	,	,	PUNCT
bjp-70889	174	60	2021	2021	NUM
bjp-70889	174	61	;	;	PUNCT
bjp-70889	174	62	gao	gao	PROPN
bjp-70889	174	63	et	et	PROPN
bjp-70889	174	64	al	al	PROPN
bjp-70889	174	65	.	.	PROPN
bjp-70889	174	66	,	,	PUNCT
bjp-70889	174	67	2022	2022	NUM
bjp-70889	174	68	)	)	PUNCT
bjp-70889	174	69	.	.	PUNCT
bjp-70889	175	1	damps	damps	AUX
bjp-70889	175	2	induce	induce	VERB
bjp-70889	175	3	the	the	DET
bjp-70889	175	4	production	production	NOUN
bjp-70889	175	5	of	of	ADP
bjp-70889	175	6	inflammatory	inflammatory	ADJ
bjp-70889	175	7	cytokines	cytokine	NOUN
bjp-70889	175	8	through	through	ADP
bjp-70889	175	9	various	various	ADJ
bjp-70889	175	10	inflammatory	inflammatory	ADJ
bjp-70889	175	11	transcriptional	transcriptional	ADJ
bjp-70889	175	12	pathways	pathway	NOUN
bjp-70889	175	13	,	,	PUNCT
bjp-70889	175	14	including	include	VERB
bjp-70889	175	15	nf	nf	NOUN
bjp-70889	175	16	-	-	PUNCT
bjp-70889	175	17	κb	κb	NOUN
bjp-70889	175	18	pathway	pathway	NOUN
bjp-70889	175	19	.	.	PUNCT
bjp-70889	176	1	necroptosis	necroptosis	NOUN
bjp-70889	176	2	contributes	contribute	VERB
bjp-70889	176	3	to	to	ADP
bjp-70889	176	4	anti	anti	ADJ
bjp-70889	176	5	-	-	ADJ
bjp-70889	176	6	tumor	tumor	ADJ
bjp-70889	176	7	effects	effect	NOUN
bjp-70889	176	8	by	by	ADP
bjp-70889	176	9	regulating	regulate	VERB
bjp-70889	176	10	the	the	DET
bjp-70889	176	11	function	function	NOUN
bjp-70889	176	12	of	of	ADP
bjp-70889	176	13	immune	immune	ADJ
bjp-70889	176	14	cells	cell	NOUN
bjp-70889	176	15	,	,	PUNCT
bjp-70889	176	16	influencing	influence	VERB
bjp-70889	176	17	their	their	PRON
bjp-70889	176	18	survival	survival	NOUN
bjp-70889	176	19	,	,	PUNCT
bjp-70889	176	20	differentiation	differentiation	NOUN
bjp-70889	176	21	,	,	PUNCT
bjp-70889	176	22	activation	activation	NOUN
bjp-70889	176	23	,	,	PUNCT
bjp-70889	176	24	transport	transport	NOUN
bjp-70889	176	25	,	,	PUNCT
bjp-70889	176	26	and	and	CCONJ
bjp-70889	176	27	functional	functional	ADJ
bjp-70889	176	28	performance	performance	NOUN
bjp-70889	176	29	(	(	PUNCT
bjp-70889	176	30	zhang	zhang	PROPN
bjp-70889	176	31	et	et	PROPN
bjp-70889	176	32	al	al	PROPN
bjp-70889	176	33	.	.	PROPN
bjp-70889	176	34	,	,	PUNCT
bjp-70889	176	35	2022	2022	NUM
bjp-70889	176	36	)	)	PUNCT
bjp-70889	176	37	.	.	PUNCT
bjp-70889	177	1	additionally	additionally	ADV
bjp-70889	177	2	,	,	PUNCT
bjp-70889	177	3	it	it	PRON
bjp-70889	177	4	induces	induce	VERB
bjp-70889	177	5	the	the	DET
bjp-70889	177	6	expression	expression	NOUN
bjp-70889	177	7	of	of	ADP
bjp-70889	177	8	immune	immune	NOUN
bjp-70889	177	9	-	-	PUNCT
bjp-70889	177	10	stimulating	stimulate	VERB
bjp-70889	177	11	cytokines	cytokine	NOUN
bjp-70889	177	12	,	,	PUNCT
bjp-70889	177	13	thereby	thereby	ADV
bjp-70889	177	14	enhan	enhan	PROPN
bjp-70889	177	15	cing	ce	VERB
bjp-70889	177	16	anti	anti	ADJ
bjp-70889	177	17	-	-	ADJ
bjp-70889	177	18	tumor	tumor	ADJ
bjp-70889	177	19	immunity	immunity	NOUN
bjp-70889	177	20	(	(	PUNCT
bjp-70889	177	21	park	park	NOUN
bjp-70889	177	22	et	et	PROPN
bjp-70889	177	23	al	al	PROPN
bjp-70889	177	24	.	.	PROPN
bjp-70889	177	25	,	,	PUNCT
bjp-70889	177	26	2021	2021	NUM
bjp-70889	177	27	)	)	PUNCT
bjp-70889	177	28	.	.	PUNCT
bjp-70889	178	1	nevertheless	nevertheless	ADV
bjp-70889	178	2	,	,	PUNCT
bjp-70889	178	3	this	this	DET
bjp-70889	178	4	study	study	NOUN
bjp-70889	178	5	lacks	lack	VERB
bjp-70889	178	6	a	a	DET
bjp-70889	178	7	detailed	detailed	ADJ
bjp-70889	178	8	exploration	exploration	NOUN
bjp-70889	178	9	of	of	ADP
bjp-70889	178	10	the	the	DET
bjp-70889	178	11	molecular	molecular	ADJ
bjp-70889	178	12	mechanism	mechanism	NOUN
bjp-70889	178	13	through	through	ADP
bjp-70889	178	14	which	which	PRON
bjp-70889	178	15	berberine	berberine	NOUN
bjp-70889	178	16	mediates	mediate	VERB
bjp-70889	178	17	its	its	PRON
bjp-70889	178	18	anti	anti	ADJ
bjp-70889	178	19	-	-	ADJ
bjp-70889	178	20	tumor	tumor	ADJ
bjp-70889	178	21	effects	effect	NOUN
bjp-70889	178	22	following	follow	VERB
bjp-70889	178	23	the	the	DET
bjp-70889	178	24	activation	activation	NOUN
bjp-70889	178	25	of	of	ADP
bjp-70889	178	26	necroptosis	necroptosis	NOUN
bjp-70889	178	27	.	.	PUNCT
bjp-70889	179	1	in	in	ADP
bjp-70889	179	2	addition	addition	NOUN
bjp-70889	179	3	,	,	PUNCT
bjp-70889	179	4	this	this	DET
bjp-70889	179	5	study	study	NOUN
bjp-70889	179	6	still	still	ADV
bjp-70889	179	7	lacks	lack	VERB
bjp-70889	179	8	mature	mature	ADJ
bjp-70889	179	9	animal	animal	NOUN
bjp-70889	179	10	models	model	NOUN
bjp-70889	179	11	to	to	PART
bjp-70889	179	12	verify	verify	VERB
bjp-70889	179	13	this	this	DET
bjp-70889	179	14	mechanism	mechanism	NOUN
bjp-70889	179	15	in	in	ADP
bjp-70889	179	16	animals	animal	NOUN
bjp-70889	179	17	.	.	PUNCT
bjp-70889	180	1	conclusion	conclusion	NOUN
bjp-70889	180	2	berberine	berberine	NOUN
bjp-70889	180	3	induces	induce	VERB
bjp-70889	180	4	necroptosis	necroptosis	NOUN
bjp-70889	180	5	in	in	ADP
bjp-70889	180	6	cervical	cervical	ADJ
bjp-70889	180	7	h8	h8	NOUN
bjp-70889	180	8	cells	cell	NOUN
bjp-70889	180	9	by	by	ADP
bjp-70889	180	10	activating	activate	VERB
bjp-70889	180	11	ripk1	ripk1	ADJ
bjp-70889	180	12	kinase	kinase	NOUN
bjp-70889	180	13	,	,	PUNCT
bjp-70889	180	14	a	a	DET
bjp-70889	180	15	process	process	NOUN
bjp-70889	180	16	independent	independent	ADJ
bjp-70889	180	17	of	of	ADP
bjp-70889	180	18	caspase	caspase	NOUN
bjp-70889	180	19	activation	activation	NOUN
bjp-70889	180	20	.	.	PUNCT
bjp-70889	181	1	these	these	DET
bjp-70889	181	2	findings	finding	NOUN
bjp-70889	181	3	present	present	VERB
bjp-70889	181	4	a	a	DET
bjp-70889	181	5	novel	novel	ADJ
bjp-70889	181	6	therapeutic	therapeutic	ADJ
bjp-70889	181	7	avenue	avenue	NOUN
bjp-70889	181	8	for	for	ADP
bjp-70889	181	9	the	the	DET
bjp-70889	181	10	prevention	prevention	NOUN
bjp-70889	181	11	and	and	CCONJ
bjp-70889	181	12	treatment	treatment	NOUN
bjp-70889	181	13	of	of	ADP
bjp-70889	181	14	cervical	cervical	ADJ
bjp-70889	181	15	intraepithelial	intraepithelial	ADJ
bjp-70889	181	16	neoplasia	neoplasia	NOUN
bjp-70889	181	17	.	.	PUNCT
bjp-70889	182	1	financial	financial	ADJ
bjp-70889	182	2	support	support	NOUN
bjp-70889	182	3	this	this	DET
bjp-70889	182	4	project	project	NOUN
bjp-70889	182	5	was	be	AUX
bjp-70889	182	6	supported	support	VERB
bjp-70889	182	7	by	by	ADP
bjp-70889	182	8	suzhou	suzhou	PROPN
bjp-70889	182	9	science	science	PROPN
bjp-70889	182	10	and	and	CCONJ
bjp-70889	182	11	technology	technology	NOUN
bjp-70889	182	12	development	development	NOUN
bjp-70889	182	13	plan	plan	NOUN
bjp-70889	182	14	project	project	NOUN
bjp-70889	182	15	(	(	PUNCT
bjp-70889	182	16	grant	grant	VERB
bjp-70889	182	17	no	no	INTJ
bjp-70889	182	18	.	.	PUNCT
bjp-70889	183	1	skyd2022071	skyd2022071	PROPN
bjp-70889	183	2	)	)	PUNCT
bjp-70889	183	3	.	.	PUNCT
bjp-70889	184	1	ethical	ethical	ADJ
bjp-70889	184	2	issue	issue	NOUN
bjp-70889	184	3	the	the	DET
bjp-70889	184	4	development	development	NOUN
bjp-70889	184	5	,	,	PUNCT
bjp-70889	184	6	acquisition	acquisition	NOUN
bjp-70889	184	7	,	,	PUNCT
bjp-70889	184	8	authentication	authentication	NOUN
bjp-70889	184	9	,	,	PUNCT
bjp-70889	184	10	cryopreservation	cryopreservation	NOUN
bjp-70889	184	11	,	,	PUNCT
bjp-70889	184	12	and	and	CCONJ
bjp-70889	184	13	transfer	transfer	NOUN
bjp-70889	184	14	of	of	ADP
bjp-70889	184	15	cell	cell	NOUN
bjp-70889	184	16	lines	line	NOUN
bjp-70889	184	17	between	between	ADP
bjp-70889	184	18	laboratories	laboratory	NOUN
bjp-70889	184	19	were	be	AUX
bjp-70889	184	20	followed	follow	VERB
bjp-70889	184	21	according	accord	VERB
bjp-70889	184	22	to	to	ADP
bjp-70889	184	23	the	the	DET
bjp-70889	184	24	guidelines	guideline	NOUN
bjp-70889	184	25	published	publish	VERB
bjp-70889	184	26	in	in	ADP
bjp-70889	184	27	british	british	ADJ
bjp-70889	184	28	journal	journal	PROPN
bjp-70889	184	29	of	of	ADP
bjp-70889	184	30	cancer	cancer	NOUN
bjp-70889	184	31	,	,	PUNCT
bjp-70889	184	32	2014	2014	NUM
bjp-70889	184	33	.	.	PUNCT
bjp-70889	185	1	conflict	conflict	NOUN
bjp-70889	185	2	of	of	ADP
bjp-70889	185	3	interest	interest	NOUN
bjp-70889	185	4	authors	author	NOUN
bjp-70889	185	5	declare	declare	VERB
bjp-70889	185	6	no	no	DET
bjp-70889	185	7	conflict	conflict	NOUN
bjp-70889	185	8	of	of	ADP
bjp-70889	185	9	interest	interest	NOUN
bjp-70889	185	10	references	reference	NOUN
bjp-70889	185	11	athanasiou	athanasiou	VERB
bjp-70889	185	12	a	a	PRON
bjp-70889	185	13	,	,	PUNCT
bjp-70889	185	14	veroniki	veroniki	ADJ
bjp-70889	185	15	aa	aa	NOUN
bjp-70889	185	16	,	,	PUNCT
bjp-70889	185	17	efthimiou	efthimiou	ADJ
bjp-70889	185	18	o	o	NOUN
bjp-70889	185	19	,	,	PUNCT
bjp-70889	185	20	kalliala	kalliala	PROPN
bjp-70889	186	1	i	i	PRON
bjp-70889	186	2	,	,	PUNCT
bjp-70889	186	3	naci	naci	PROPN
bjp-70889	186	4	h	h	PROPN
bjp-70889	186	5	,	,	PUNCT
bjp-70889	186	6	bowden	bowden	PROPN
bjp-70889	186	7	s	s	PROPN
bjp-70889	186	8	,	,	PUNCT
bjp-70889	186	9	paraskevaidi	paraskevaidi	PROPN
bjp-70889	186	10	m	m	PROPN
bjp-70889	186	11	,	,	PUNCT
bjp-70889	186	12	arbyn	arbyn	PROPN
bjp-70889	186	13	m	m	PROPN
bjp-70889	186	14	,	,	PUNCT
bjp-70889	186	15	lyons	lyons	PROPN
bjp-70889	186	16	d	d	PROPN
bjp-70889	186	17	,	,	PUNCT
bjp-70889	186	18	martinhirsch	martinhirsch	ADV
bjp-70889	186	19	p	p	X
bjp-70889	186	20	,	,	PUNCT
bjp-70889	186	21	bennett	bennett	PROPN
bjp-70889	186	22	p	p	PROPN
bjp-70889	186	23	,	,	PUNCT
bjp-70889	186	24	paraskevaidis	paraskevaidi	NOUN
bjp-70889	186	25	e	e	NOUN
bjp-70889	186	26	,	,	PUNCT
bjp-70889	186	27	salanti	salanti	ADJ
bjp-70889	186	28	g	g	NOUN
bjp-70889	186	29	,	,	PUNCT
bjp-70889	186	30	kyrgiou	kyrgiou	NOUN
bjp-70889	186	31	m.	m.	NOUN
bjp-70889	186	32	comparative	comparative	ADJ
bjp-70889	186	33	effectiveness	effectiveness	NOUN
bjp-70889	186	34	and	and	CCONJ
bjp-70889	186	35	risk	risk	NOUN
bjp-70889	186	36	of	of	ADP
bjp-70889	186	37	preterm	preterm	ADJ
bjp-70889	186	38	birth	birth	NOUN
bjp-70889	186	39	of	of	ADP
bjp-70889	186	40	local	local	ADJ
bjp-70889	186	41	treatments	treatment	NOUN
bjp-70889	186	42	for	for	ADP
bjp-70889	186	43	cervical	cervical	ADJ
bjp-70889	186	44	intraepithelial	intraepithelial	ADJ
bjp-70889	186	45	neoplasia	neoplasia	NOUN
bjp-70889	186	46	and	and	CCONJ
bjp-70889	186	47	stage	stage	VERB
bjp-70889	186	48	ia1	ia1	NOUN
bjp-70889	186	49	cervical	cervical	ADJ
bjp-70889	186	50	cancer	cancer	NOUN
bjp-70889	186	51	:	:	PUNCT
bjp-70889	186	52	a	a	DET
bjp-70889	186	53	systematic	systematic	ADJ
bjp-70889	186	54	review	review	NOUN
bjp-70889	186	55	and	and	CCONJ
bjp-70889	186	56	network	network	NOUN
bjp-70889	186	57	metaanalysis	metaanalysis	NOUN
bjp-70889	186	58	.	.	PUNCT
bjp-70889	187	1	lancet	lancet	PROPN
bjp-70889	187	2	oncol	oncol	PROPN
bjp-70889	187	3	.	.	PUNCT
bjp-70889	188	1	2022	2022	NUM
bjp-70889	188	2	;	;	PUNCT
bjp-70889	188	3	23	23	NUM
bjp-70889	188	4	:	:	SYM
bjp-70889	188	5	1097	1097	NUM
bjp-70889	188	6	-	-	SYM
bjp-70889	188	7	108	108	NUM
bjp-70889	188	8	.	.	PUNCT
bjp-70889	189	1	bertheloot	bertheloot	PROPN
bjp-70889	189	2	d	d	PROPN
bjp-70889	189	3	,	,	PUNCT
bjp-70889	189	4	latz	latz	ADJ
bjp-70889	189	5	e	e	NOUN
bjp-70889	189	6	,	,	PUNCT
bjp-70889	189	7	franklin	franklin	PROPN
bjp-70889	189	8	bs	bs	PROPN
bjp-70889	189	9	.	.	PROPN
bjp-70889	189	10	necroptosis	necroptosis	PROPN
bjp-70889	189	11	,	,	PUNCT
bjp-70889	189	12	pyroptosis	pyroptosis	NOUN
bjp-70889	189	13	and	and	CCONJ
bjp-70889	189	14	apoptosis	apoptosis	NOUN
bjp-70889	189	15	:	:	PUNCT
bjp-70889	189	16	an	an	DET
bjp-70889	189	17	intricate	intricate	ADJ
bjp-70889	189	18	game	game	NOUN
bjp-70889	189	19	of	of	ADP
bjp-70889	189	20	cell	cell	NOUN
bjp-70889	189	21	death	death	NOUN
bjp-70889	189	22	.	.	PUNCT
bjp-70889	190	1	cell	cell	NOUN
bjp-70889	190	2	mol	mol	ADP
bjp-70889	190	3	figure	figure	NOUN
bjp-70889	190	4	3	3	NUM
bjp-70889	190	5	:	:	SYM
bjp-70889	190	6	3d	3d	NUM
bjp-70889	190	7	diagram	diagram	NOUN
bjp-70889	190	8	of	of	ADP
bjp-70889	190	9	binding	bind	VERB
bjp-70889	190	10	orientation	orientation	NOUN
bjp-70889	190	11	tion	tion	NOUN
bjp-70889	190	12	of	of	ADP
bjp-70889	190	13	the	the	DET
bjp-70889	190	14	compound	compound	NOUN
bjp-70889	190	15	(	(	PUNCT
bjp-70889	190	16	c	c	NOUN
bjp-70889	190	17	)	)	PUNCT
bjp-70889	190	18	20	20	NUM
bjp-70889	190	19	bangladesh	bangladesh	PROPN
bjp-70889	190	20	j	j	PROPN
bjp-70889	190	21	pharmacol	pharmacol	PROPN
bjp-70889	190	22	2024	2024	NUM
bjp-70889	190	23	;	;	PUNCT
bjp-70889	190	24	19	19	NUM
bjp-70889	190	25	:	:	SYM
bjp-70889	190	26	13	13	NUM
bjp-70889	190	27	-	-	SYM
bjp-70889	190	28	22	22	NUM
bjp-70889	190	29	immunol	immunol	NOUN
bjp-70889	190	30	.	.	PUNCT
bjp-70889	190	31	2021	2021	NUM
bjp-70889	190	32	;	;	PUNCT
bjp-70889	190	33	18	18	NUM
bjp-70889	190	34	:	:	SYM
bjp-70889	190	35	1106	1106	NUM
bjp-70889	190	36	-	-	SYM
bjp-70889	190	37	21	21	NUM
bjp-70889	190	38	.	.	PUNCT
bjp-70889	191	1	chen	chen	PROPN
bjp-70889	191	2	x	x	PROPN
bjp-70889	191	3	,	,	PUNCT
bjp-70889	191	4	hu	hu	PROPN
bjp-70889	191	5	x	x	PROPN
bjp-70889	191	6	,	,	PUNCT
bjp-70889	191	7	liu	liu	PROPN
bjp-70889	191	8	l	l	PROPN
bjp-70889	191	9	,	,	PUNCT
bjp-70889	191	10	liang	liang	PROPN
bjp-70889	191	11	x	x	PROPN
bjp-70889	191	12	,	,	PUNCT
bjp-70889	191	13	xiao	xiao	PROPN
bjp-70889	191	14	j.	j.	PROPN
bjp-70889	191	15	extracts	extract	NOUN
bjp-70889	191	16	derived	derive	VERB
bjp-70889	191	17	from	from	ADP
bjp-70889	191	18	a	a	DET
bjp-70889	191	19	traditional	traditional	ADJ
bjp-70889	191	20	chinese	chinese	ADJ
bjp-70889	191	21	herbal	herbal	ADJ
bjp-70889	191	22	formula	formula	NOUN
bjp-70889	191	23	triggers	trigger	NOUN
bjp-70889	191	24	necroptosis	necroptosis	NOUN
bjp-70889	191	25	in	in	ADP
bjp-70889	191	26	ectocervical	ectocervical	ADJ
bjp-70889	191	27	ect1	ect1	PROPN
bjp-70889	191	28	/	/	SYM
bjp-70889	191	29	e6e7	e6e7	PROPN
bjp-70889	191	30	cells	cell	NOUN
bjp-70889	191	31	through	through	ADP
bjp-70889	191	32	activation	activation	NOUN
bjp-70889	191	33	of	of	ADP
bjp-70889	191	34	rip1	rip1	PROPN
bjp-70889	191	35	kinase	kinase	PROPN
bjp-70889	191	36	.	.	PUNCT
bjp-70889	192	1	j	j	PROPN
bjp-70889	192	2	ethnopharmacol	ethnopharmacol	PROPN
bjp-70889	192	3	.	.	PROPN
bjp-70889	193	1	2019	2019	NUM
bjp-70889	193	2	;	;	PUNCT
bjp-70889	193	3	239	239	NUM
bjp-70889	193	4	:	:	SYM
bjp-70889	193	5	111922	111922	NUM
bjp-70889	193	6	.	.	PUNCT
bjp-70889	194	1	doorbar	doorbar	PROPN
bjp-70889	194	2	j	j	PROPN
bjp-70889	194	3	,	,	PUNCT
bjp-70889	194	4	egawa	egawa	PROPN
bjp-70889	194	5	n	n	CCONJ
bjp-70889	194	6	,	,	PUNCT
bjp-70889	194	7	griffin	griffin	PROPN
bjp-70889	194	8	h	h	PROPN
bjp-70889	194	9	,	,	PUNCT
bjp-70889	194	10	kranjec	kranjec	PROPN
bjp-70889	194	11	c	c	NOUN
bjp-70889	194	12	,	,	PUNCT
bjp-70889	194	13	murakami	murakami	PROPN
bjp-70889	194	14	i.	i.	PROPN
bjp-70889	194	15	human	human	PROPN
bjp-70889	194	16	papillomavirus	papillomavirus	PROPN
bjp-70889	194	17	molecular	molecular	ADJ
bjp-70889	194	18	biology	biology	NOUN
bjp-70889	194	19	and	and	CCONJ
bjp-70889	194	20	disease	disease	NOUN
bjp-70889	194	21	association	association	PROPN
bjp-70889	194	22	.	.	PUNCT
bjp-70889	195	1	rev	rev	PROPN
bjp-70889	195	2	med	med	PROPN
bjp-70889	195	3	virol	virol	NOUN
bjp-70889	195	4	.	.	PUNCT
bjp-70889	196	1	2015	2015	NUM
bjp-70889	196	2	;	;	PUNCT
bjp-70889	196	3	25	25	NUM
bjp-70889	196	4	suppl	suppl	ADJ
bjp-70889	196	5	1	1	NUM
bjp-70889	196	6	:	:	SYM
bjp-70889	196	7	2	2	NUM
bjp-70889	196	8	-	-	SYM
bjp-70889	196	9	23	23	NUM
bjp-70889	196	10	.	.	PUNCT
bjp-70889	197	1	feng	feng	PROPN
bjp-70889	197	2	x	x	PROPN
bjp-70889	197	3	,	,	PUNCT
bjp-70889	197	4	song	song	NOUN
bjp-70889	197	5	q	q	PROPN
bjp-70889	197	6	,	,	PUNCT
bjp-70889	197	7	yu	yu	PROPN
bjp-70889	197	8	a	a	PRON
bjp-70889	197	9	,	,	PUNCT
bjp-70889	197	10	tang	tang	PROPN
bjp-70889	197	11	h	h	NOUN
bjp-70889	197	12	,	,	PUNCT
bjp-70889	197	13	peng	peng	PROPN
bjp-70889	197	14	z	z	PROPN
bjp-70889	197	15	,	,	PUNCT
bjp-70889	197	16	wang	wang	PROPN
bjp-70889	197	17	x.	x.	PROPN
bjp-70889	197	18	receptorinteracting	receptorinteracte	VERB
bjp-70889	197	19	protein	protein	NOUN
bjp-70889	197	20	kinase	kinase	PROPN
bjp-70889	197	21	3	3	NUM
bjp-70889	197	22	is	be	AUX
bjp-70889	197	23	a	a	DET
bjp-70889	197	24	predictor	predictor	NOUN
bjp-70889	197	25	of	of	ADP
bjp-70889	197	26	survival	survival	NOUN
bjp-70889	197	27	and	and	CCONJ
bjp-70889	197	28	plays	play	VERB
bjp-70889	197	29	a	a	DET
bjp-70889	197	30	tumor	tumor	NOUN
bjp-70889	197	31	suppressive	suppressive	ADJ
bjp-70889	197	32	role	role	NOUN
bjp-70889	197	33	in	in	ADP
bjp-70889	197	34	colorectal	colorectal	ADJ
bjp-70889	197	35	cancer	cancer	NOUN
bjp-70889	197	36	.	.	PUNCT
bjp-70889	198	1	neoplasma	neoplasma	PROPN
bjp-70889	198	2	2015	2015	NUM
bjp-70889	198	3	;	;	PUNCT
bjp-70889	198	4	62	62	NUM
bjp-70889	198	5	:	:	PUNCT
bjp-70889	198	6	592	592	NUM
bjp-70889	198	7	-	-	SYM
bjp-70889	198	8	601	601	NUM
bjp-70889	198	9	.	.	PUNCT
bjp-70889	199	1	feoktistova	feoktistova	PROPN
bjp-70889	199	2	m	m	PROPN
bjp-70889	199	3	,	,	PUNCT
bjp-70889	199	4	leverkus	leverkus	PROPN
bjp-70889	199	5	m.	m.	NOUN
bjp-70889	199	6	programmed	program	VERB
bjp-70889	199	7	necrosis	necrosis	NOUN
bjp-70889	199	8	and	and	CCONJ
bjp-70889	199	9	necroptosis	necroptosis	NOUN
bjp-70889	199	10	signalling	signal	VERB
bjp-70889	199	11	.	.	PUNCT
bjp-70889	200	1	febs	febs	PROPN
bjp-70889	200	2	j.	j.	PROPN
bjp-70889	200	3	2015	2015	NUM
bjp-70889	200	4	;	;	PUNCT
bjp-70889	200	5	282	282	NUM
bjp-70889	200	6	:	:	SYM
bjp-70889	200	7	19	19	NUM
bjp-70889	200	8	-	-	SYM
bjp-70889	200	9	31	31	NUM
bjp-70889	200	10	.	.	PUNCT
bjp-70889	201	1	floriano	floriano	PROPN
bjp-70889	201	2	bf	bf	PROPN
bjp-70889	201	3	,	,	PUNCT
bjp-70889	201	4	carvalho	carvalho	PROPN
bjp-70889	201	5	t	t	PROPN
bjp-70889	201	6	,	,	PUNCT
bjp-70889	201	7	lopes	lopes	PROPN
bjp-70889	201	8	tz	tz	PROPN
bjp-70889	201	9	,	,	PUNCT
bjp-70889	201	10	takahashi	takahashi	PROPN
bjp-70889	201	11	l	l	PROPN
bjp-70889	201	12	,	,	PUNCT
bjp-70889	201	13	rahal	rahal	VERB
bjp-70889	201	14	p	p	PROPN
bjp-70889	201	15	,	,	PUNCT
bjp-70889	201	16	tedesco	tedesco	PROPN
bjp-70889	201	17	ac	ac	PROPN
bjp-70889	201	18	,	,	PUNCT
bjp-70889	201	19	calmon	calmon	ADJ
bjp-70889	201	20	mf	mf	NOUN
bjp-70889	201	21	.	.	PROPN
bjp-70889	201	22	effect	effect	NOUN
bjp-70889	201	23	of	of	ADP
bjp-70889	201	24	berberine	berberine	NOUN
bjp-70889	201	25	nanoemulsion	nanoemulsion	NOUN
bjp-70889	201	26	photodynamic	photodynamic	ADJ
bjp-70889	201	27	therapy	therapy	NOUN
bjp-70889	201	28	on	on	ADP
bjp-70889	201	29	cervical	cervical	ADJ
bjp-70889	201	30	carcinoma	carcinoma	NOUN
bjp-70889	201	31	cell	cell	NOUN
bjp-70889	201	32	line	line	NOUN
bjp-70889	201	33	.	.	PUNCT
bjp-70889	202	1	photodiagnosis	photodiagnosis	NOUN
bjp-70889	202	2	photodyn	photodyn	PROPN
bjp-70889	202	3	ther	ther	ADV
bjp-70889	202	4	.	.	PUNCT
bjp-70889	203	1	2021	2021	NUM
bjp-70889	203	2	;	;	PUNCT
bjp-70889	203	3	33	33	NUM
bjp-70889	203	4	:	:	SYM
bjp-70889	203	5	102174	102174	NUM
bjp-70889	203	6	.	.	PUNCT
bjp-70889	204	1	gao	gao	PROPN
bjp-70889	204	2	w	w	PROPN
bjp-70889	204	3	,	,	PUNCT
bjp-70889	204	4	wang	wang	PROPN
bjp-70889	204	5	x	x	PROPN
bjp-70889	204	6	,	,	PUNCT
bjp-70889	204	7	zhou	zhou	PROPN
bjp-70889	204	8	y	y	PROPN
bjp-70889	204	9	,	,	PUNCT
bjp-70889	204	10	wang	wang	PROPN
bjp-70889	204	11	x	x	PROPN
bjp-70889	204	12	,	,	PUNCT
bjp-70889	204	13	yu	yu	PROPN
bjp-70889	204	14	y.	y.	PROPN
bjp-70889	204	15	autophagy	autophagy	PROPN
bjp-70889	204	16	,	,	PUNCT
bjp-70889	204	17	ferroptosis	ferroptosis	NOUN
bjp-70889	204	18	,	,	PUNCT
bjp-70889	204	19	pyroptosis	pyroptosis	NOUN
bjp-70889	204	20	,	,	PUNCT
bjp-70889	204	21	and	and	CCONJ
bjp-70889	204	22	necroptosis	necroptosis	NOUN
bjp-70889	204	23	in	in	ADP
bjp-70889	204	24	tumor	tumor	NOUN
bjp-70889	204	25	immunotherapy	immunotherapy	NOUN
bjp-70889	204	26	.	.	PUNCT
bjp-70889	205	1	signal	signal	PROPN
bjp-70889	205	2	transduct	transduct	NOUN
bjp-70889	205	3	target	target	NOUN
bjp-70889	205	4	ther	ther	ADV
bjp-70889	205	5	.	.	PUNCT
bjp-70889	206	1	2022	2022	NUM
bjp-70889	206	2	;	;	PUNCT
bjp-70889	206	3	7	7	NUM
bjp-70889	206	4	:	:	SYM
bjp-70889	206	5	196	196	NUM
bjp-70889	206	6	.	.	PUNCT
bjp-70889	207	1	ghaem	ghaem	NOUN
bjp-70889	207	2	-	-	PUNCT
bjp-70889	207	3	maghami	maghami	PROPN
bjp-70889	207	4	s	s	PROPN
bjp-70889	207	5	,	,	PUNCT
bjp-70889	207	6	sagi	sagi	PROPN
bjp-70889	207	7	s	s	PROPN
bjp-70889	207	8	,	,	PUNCT
bjp-70889	207	9	majeed	majeed	PROPN
bjp-70889	207	10	g	g	PROPN
bjp-70889	207	11	,	,	PUNCT
bjp-70889	207	12	soutter	soutter	PROPN
bjp-70889	207	13	wp	wp	PROPN
bjp-70889	207	14	.	.	PUNCT
bjp-70889	208	1	incomplete	incomplete	ADJ
bjp-70889	208	2	excision	excision	NOUN
bjp-70889	208	3	of	of	ADP
bjp-70889	208	4	cervical	cervical	ADJ
bjp-70889	208	5	intraepithelial	intraepithelial	ADJ
bjp-70889	208	6	neoplasia	neoplasia	NOUN
bjp-70889	208	7	and	and	CCONJ
bjp-70889	208	8	risk	risk	NOUN
bjp-70889	208	9	of	of	ADP
bjp-70889	208	10	treatment	treatment	NOUN
bjp-70889	208	11	failure	failure	NOUN
bjp-70889	208	12	:	:	PUNCT
bjp-70889	208	13	a	a	DET
bjp-70889	208	14	meta	meta	ADJ
bjp-70889	208	15	-	-	PUNCT
bjp-70889	208	16	analysis	analysis	NOUN
bjp-70889	208	17	.	.	PUNCT
bjp-70889	209	1	lancet	lancet	PROPN
bjp-70889	209	2	oncol	oncol	PROPN
bjp-70889	209	3	.	.	PUNCT
bjp-70889	210	1	2007	2007	NUM
bjp-70889	210	2	;	;	PUNCT
bjp-70889	210	3	8	8	NUM
bjp-70889	210	4	:	:	SYM
bjp-70889	210	5	985	985	NUM
bjp-70889	210	6	-	-	SYM
bjp-70889	210	7	93	93	NUM
bjp-70889	210	8	.	.	PUNCT
bjp-70889	211	1	hoffman	hoffman	PROPN
bjp-70889	211	2	sr	sr	PROPN
bjp-70889	211	3	,	,	PUNCT
bjp-70889	211	4	le	le	PROPN
bjp-70889	211	5	t	t	PROPN
bjp-70889	211	6	,	,	PUNCT
bjp-70889	211	7	lockhart	lockhart	PROPN
bjp-70889	211	8	a	a	PROPN
bjp-70889	211	9	,	,	PUNCT
bjp-70889	211	10	sanusi	sanusi	NOUN
bjp-70889	211	11	a	a	NOUN
bjp-70889	211	12	,	,	PUNCT
bjp-70889	211	13	dal	dal	NOUN
bjp-70889	211	14	santo	santo	PROPN
bjp-70889	211	15	l	l	PROPN
bjp-70889	211	16	,	,	PUNCT
bjp-70889	211	17	davis	davis	PROPN
bjp-70889	211	18	m	m	PROPN
bjp-70889	211	19	,	,	PUNCT
bjp-70889	211	20	mckinney	mckinney	PROPN
bjp-70889	211	21	da	da	PROPN
bjp-70889	211	22	,	,	PUNCT
bjp-70889	211	23	brown	brown	PROPN
bjp-70889	211	24	m	m	PROPN
bjp-70889	211	25	,	,	PUNCT
bjp-70889	211	26	poole	poole	PROPN
bjp-70889	211	27	c	c	PROPN
bjp-70889	211	28	,	,	PUNCT
bjp-70889	211	29	willame	willame	VERB
bjp-70889	211	30	c	c	PROPN
bjp-70889	211	31	,	,	PUNCT
bjp-70889	211	32	smith	smith	PROPN
bjp-70889	211	33	js	js	PROPN
bjp-70889	211	34	.	.	PUNCT
bjp-70889	212	1	patterns	pattern	NOUN
bjp-70889	212	2	of	of	ADP
bjp-70889	212	3	persistent	persistent	ADJ
bjp-70889	212	4	hpv	hpv	ADJ
bjp-70889	212	5	infection	infection	NOUN
bjp-70889	212	6	after	after	ADP
bjp-70889	212	7	treatment	treatment	NOUN
bjp-70889	212	8	for	for	ADP
bjp-70889	212	9	cervical	cervical	ADJ
bjp-70889	212	10	intraepithelial	intraepithelial	ADJ
bjp-70889	212	11	neoplasia	neoplasia	NOUN
bjp-70889	212	12	(	(	PUNCT
bjp-70889	212	13	cin	cin	PROPN
bjp-70889	212	14	):	):	PUNCT
bjp-70889	212	15	a	a	DET
bjp-70889	212	16	systematic	systematic	ADJ
bjp-70889	212	17	review	review	NOUN
bjp-70889	212	18	.	.	PUNCT
bjp-70889	213	1	int	int	NOUN
bjp-70889	213	2	j	j	PROPN
bjp-70889	213	3	cancer	cancer	NOUN
bjp-70889	213	4	.	.	PUNCT
bjp-70889	214	1	2017	2017	NUM
bjp-70889	214	2	;	;	PUNCT
bjp-70889	214	3	141	141	NUM
bjp-70889	214	4	:	:	SYM
bjp-70889	214	5	8	8	NUM
bjp-70889	214	6	-	-	SYM
bjp-70889	214	7	23	23	NUM
bjp-70889	214	8	.	.	PUNCT
bjp-70889	215	1	jie	jie	PROPN
bjp-70889	215	2	h	h	PROPN
bjp-70889	215	3	,	,	PUNCT
bjp-70889	215	4	he	he	PRON
bjp-70889	215	5	y	y	PROPN
bjp-70889	215	6	,	,	PUNCT
bjp-70889	215	7	huang	huang	PROPN
bjp-70889	215	8	x	x	PROPN
bjp-70889	215	9	,	,	PUNCT
bjp-70889	215	10	zhou	zhou	PROPN
bjp-70889	215	11	q	q	PROPN
bjp-70889	215	12	,	,	PUNCT
bjp-70889	215	13	han	han	PROPN
bjp-70889	215	14	y	y	PROPN
bjp-70889	215	15	,	,	PUNCT
bjp-70889	215	16	li	li	PROPN
bjp-70889	215	17	x	x	PROPN
bjp-70889	215	18	,	,	PUNCT
bjp-70889	215	19	bai	bai	PROPN
bjp-70889	215	20	y	y	PROPN
bjp-70889	215	21	,	,	PUNCT
bjp-70889	215	22	sun	sun	PROPN
bjp-70889	215	23	e.	e.	PROPN
bjp-70889	215	24	necrostatin-1	necrostatin-1	NUM
bjp-70889	215	25	enhances	enhance	VERB
bjp-70889	215	26	the	the	DET
bjp-70889	215	27	resolution	resolution	NOUN
bjp-70889	215	28	of	of	ADP
bjp-70889	215	29	inflammation	inflammation	NOUN
bjp-70889	215	30	by	by	ADP
bjp-70889	215	31	specifically	specifically	ADV
bjp-70889	215	32	inducing	induce	VERB
bjp-70889	215	33	neutrophil	neutrophil	ADJ
bjp-70889	215	34	apoptosis	apoptosis	NOUN
bjp-70889	215	35	.	.	PUNCT
bjp-70889	216	1	oncotarget	oncotarget	NOUN
bjp-70889	216	2	2016	2016	NUM
bjp-70889	216	3	;	;	PUNCT
bjp-70889	216	4	7	7	NUM
bjp-70889	216	5	:	:	SYM
bjp-70889	216	6	19367	19367	NUM
bjp-70889	216	7	-	-	SYM
bjp-70889	216	8	81	81	NUM
bjp-70889	216	9	.	.	PUNCT
bjp-70889	217	1	kaczmarek	kaczmarek	PROPN
bjp-70889	217	2	a	a	X
bjp-70889	217	3	,	,	PUNCT
bjp-70889	217	4	vandenabeele	vandenabeele	NOUN
bjp-70889	217	5	p	p	NOUN
bjp-70889	217	6	,	,	PUNCT
bjp-70889	217	7	krysko	krysko	PROPN
bjp-70889	217	8	dv	dv	PROPN
bjp-70889	217	9	.	.	PROPN
bjp-70889	217	10	necroptosis	necroptosis	PROPN
bjp-70889	217	11	:	:	PUNCT
bjp-70889	217	12	the	the	DET
bjp-70889	217	13	release	release	NOUN
bjp-70889	217	14	of	of	ADP
bjp-70889	217	15	damage	damage	NOUN
bjp-70889	217	16	-	-	PUNCT
bjp-70889	217	17	associated	associate	VERB
bjp-70889	217	18	molecular	molecular	ADJ
bjp-70889	217	19	patterns	pattern	NOUN
bjp-70889	217	20	and	and	CCONJ
bjp-70889	217	21	its	its	PRON
bjp-70889	217	22	physiological	physiological	ADJ
bjp-70889	217	23	relevance	relevance	NOUN
bjp-70889	217	24	.	.	PUNCT
bjp-70889	218	1	immunity	immunity	NOUN
bjp-70889	218	2	2013	2013	NUM
bjp-70889	218	3	;	;	PUNCT
bjp-70889	218	4	38	38	NUM
bjp-70889	218	5	:	:	SYM
bjp-70889	218	6	209	209	NUM
bjp-70889	218	7	-	-	SYM
bjp-70889	218	8	23	23	NUM
bjp-70889	218	9	.	.	PUNCT
bjp-70889	219	1	kim	kim	PROPN
bjp-70889	219	2	jh	jh	PROPN
bjp-70889	219	3	,	,	PUNCT
bjp-70889	219	4	weeratunga	weeratunga	VERB
bjp-70889	219	5	p	p	X
bjp-70889	219	6	,	,	PUNCT
bjp-70889	219	7	kim	kim	PROPN
bjp-70889	219	8	ms	ms	PROPN
bjp-70889	219	9	,	,	PUNCT
bjp-70889	219	10	nikapitiya	nikapitiya	PROPN
bjp-70889	219	11	c	c	PROPN
bjp-70889	219	12	,	,	PUNCT
bjp-70889	219	13	lee	lee	PROPN
bjp-70889	219	14	bh	bh	PROPN
bjp-70889	219	15	,	,	PUNCT
bjp-70889	219	16	uddin	uddin	PROPN
bjp-70889	219	17	mb	mb	ADP
bjp-70889	219	18	,	,	PUNCT
bjp-70889	219	19	kim	kim	PROPN
bjp-70889	219	20	th	th	PROPN
bjp-70889	219	21	,	,	PUNCT
bjp-70889	219	22	yoon	yoon	PROPN
bjp-70889	219	23	je	je	PROPN
bjp-70889	219	24	,	,	PUNCT
bjp-70889	219	25	park	park	PROPN
bjp-70889	219	26	c	c	PROPN
bjp-70889	219	27	,	,	PUNCT
bjp-70889	219	28	ma	ma	PROPN
bjp-70889	219	29	jy	jy	PROPN
bjp-70889	219	30	,	,	PUNCT
bjp-70889	219	31	kim	kim	PROPN
bjp-70889	219	32	h	h	PROPN
bjp-70889	219	33	,	,	PUNCT
bjp-70889	219	34	lee	lee	PROPN
bjp-70889	219	35	js	js	PROPN
bjp-70889	219	36	.	.	PUNCT
bjp-70889	220	1	inhibitory	inhibitory	ADJ
bjp-70889	220	2	effects	effect	NOUN
bjp-70889	220	3	of	of	ADP
bjp-70889	220	4	an	an	DET
bjp-70889	220	5	aqueous	aqueous	ADJ
bjp-70889	220	6	extract	extract	NOUN
bjp-70889	220	7	from	from	ADP
bjp-70889	220	8	cortex	cortex	NOUN
bjp-70889	220	9	phellodendri	phellodendri	NOUN
bjp-70889	220	10	on	on	ADP
bjp-70889	220	11	the	the	DET
bjp-70889	220	12	growth	growth	NOUN
bjp-70889	220	13	and	and	CCONJ
bjp-70889	220	14	replication	replication	NOUN
bjp-70889	220	15	of	of	ADP
bjp-70889	220	16	broadspectrum	broadspectrum	NOUN
bjp-70889	220	17	of	of	ADP
bjp-70889	220	18	viruses	virus	NOUN
bjp-70889	220	19	in	in	ADP
bjp-70889	220	20	vitro	vitro	X
bjp-70889	220	21	and	and	CCONJ
bjp-70889	220	22	in	in	ADP
bjp-70889	220	23	vivo	vivo	NOUN
bjp-70889	220	24	.	.	PUNCT
bjp-70889	221	1	bmc	bmc	PROPN
bjp-70889	221	2	complement	complement	PROPN
bjp-70889	221	3	altern	altern	NOUN
bjp-70889	221	4	med	med	PROPN
bjp-70889	221	5	2016	2016	NUM
bjp-70889	221	6	;	;	PUNCT
bjp-70889	221	7	16	16	NUM
bjp-70889	221	8	:	:	SYM
bjp-70889	221	9	265	265	NUM
bjp-70889	221	10	.	.	PUNCT
bjp-70889	222	1	li	li	PROPN
bjp-70889	223	1	q	q	PROPN
bjp-70889	223	2	,	,	PUNCT
bjp-70889	223	3	zhao	zhao	PROPN
bjp-70889	223	4	h	h	PROPN
bjp-70889	223	5	,	,	PUNCT
bjp-70889	223	6	chen	chen	PROPN
bjp-70889	223	7	w	w	PROPN
bjp-70889	223	8	,	,	PUNCT
bjp-70889	223	9	huang	huang	PROPN
bjp-70889	223	10	p.	p.	PROPN
bjp-70889	223	11	berberine	berberine	PROPN
bjp-70889	223	12	induces	induce	VERB
bjp-70889	223	13	apoptosis	apoptosis	NOUN
bjp-70889	223	14	and	and	CCONJ
bjp-70889	223	15	arrests	arrest	NOUN
bjp-70889	223	16	the	the	DET
bjp-70889	223	17	cell	cell	NOUN
bjp-70889	223	18	cycle	cycle	NOUN
bjp-70889	223	19	in	in	ADP
bjp-70889	223	20	multiple	multiple	ADJ
bjp-70889	223	21	cancer	cancer	NOUN
bjp-70889	223	22	cell	cell	NOUN
bjp-70889	223	23	lines	line	NOUN
bjp-70889	223	24	.	.	PUNCT
bjp-70889	224	1	arch	arch	PROPN
bjp-70889	224	2	med	med	PROPN
bjp-70889	224	3	sci	sci	PROPN
bjp-70889	224	4	.	.	PROPN
bjp-70889	224	5	2023	2023	NUM
bjp-70889	224	6	;	;	PUNCT
bjp-70889	224	7	19	19	NUM
bjp-70889	224	8	:	:	SYM
bjp-70889	224	9	1530	1530	NUM
bjp-70889	224	10	-	-	SYM
bjp-70889	224	11	37	37	NUM
bjp-70889	224	12	.	.	PUNCT
bjp-70889	225	1	liontos	liontos	PROPN
bjp-70889	225	2	m	m	PROPN
bjp-70889	225	3	,	,	PUNCT
bjp-70889	225	4	kyriazoglou	kyriazoglou	PROPN
bjp-70889	225	5	a	a	PROPN
bjp-70889	225	6	,	,	PUNCT
bjp-70889	225	7	dimitriadis	dimitriadis	VERB
bjp-70889	225	8	i	i	PRON
bjp-70889	225	9	,	,	PUNCT
bjp-70889	225	10	dimopoulos	dimopoulos	PROPN
bjp-70889	225	11	ma	ma	PROPN
bjp-70889	225	12	,	,	PUNCT
bjp-70889	225	13	bamias	bamias	ADJ
bjp-70889	225	14	a.	a.	NOUN
bjp-70889	225	15	systemic	systemic	ADJ
bjp-70889	225	16	therapy	therapy	NOUN
bjp-70889	225	17	in	in	ADP
bjp-70889	225	18	cervical	cervical	ADJ
bjp-70889	225	19	cancer	cancer	NOUN
bjp-70889	225	20	:	:	PUNCT
bjp-70889	225	21	30	30	NUM
bjp-70889	225	22	years	year	NOUN
bjp-70889	225	23	in	in	ADP
bjp-70889	225	24	review	review	NOUN
bjp-70889	225	25	.	.	PUNCT
bjp-70889	226	1	crit	crit	PROPN
bjp-70889	226	2	rev	rev	VERB
bjp-70889	226	3	oncol	oncol	ADJ
bjp-70889	226	4	hematol	hematol	NOUN
bjp-70889	226	5	.	.	PUNCT
bjp-70889	227	1	2019	2019	NUM
bjp-70889	227	2	;	;	PUNCT
bjp-70889	227	3	137	137	NUM
bjp-70889	227	4	:	:	PUNCT
bjp-70889	227	5	9	9	NUM
bjp-70889	227	6	-	-	SYM
bjp-70889	227	7	17	17	NUM
bjp-70889	227	8	.	.	PUNCT
bjp-70889	228	1	lim	lim	PROPN
bjp-70889	228	2	hs	hs	PROPN
bjp-70889	228	3	,	,	PUNCT
bjp-70889	228	4	moon	moon	PROPN
bjp-70889	228	5	bc	bc	PROPN
bjp-70889	228	6	,	,	PUNCT
bjp-70889	228	7	park	park	PROPN
bjp-70889	228	8	g.	g.	PROPN
bjp-70889	228	9	nrf2	nrf2	PROPN
bjp-70889	228	10	signaling	signal	VERB
bjp-70889	228	11	contributes	contribute	VERB
bjp-70889	228	12	to	to	ADP
bjp-70889	228	13	the	the	DET
bjp-70889	228	14	neuroprotective	neuroprotective	ADJ
bjp-70889	228	15	effect	effect	NOUN
bjp-70889	228	16	of	of	ADP
bjp-70889	228	17	cicadidae	cicadidae	ADP
bjp-70889	228	18	periostracum	periostracum	NOUN
bjp-70889	228	19	against	against	ADP
bjp-70889	228	20	1methyl-4	1methyl-4	NUM
bjp-70889	228	21	-	-	SYM
bjp-70889	228	22	phenyl-1	phenyl-1	NUM
bjp-70889	228	23	,	,	PUNCT
bjp-70889	228	24	2	2	NUM
bjp-70889	228	25	,	,	PUNCT
bjp-70889	228	26	3	3	NUM
bjp-70889	228	27	,	,	PUNCT
bjp-70889	228	28	6	6	NUM
bjp-70889	228	29	-	-	PUNCT
bjp-70889	228	30	tetrahydropyridine	tetrahydropyridine	ADJ
bjp-70889	228	31	toxicity	toxicity	NOUN
bjp-70889	228	32	.	.	PUNCT
bjp-70889	229	1	bangladesh	bangladesh	PROPN
bjp-70889	229	2	j	j	PROPN
bjp-70889	229	3	pharmacol	pharmacol	PROPN
bjp-70889	229	4	.	.	PUNCT
bjp-70889	230	1	2022	2022	NUM
bjp-70889	230	2	;	;	PUNCT
bjp-70889	230	3	17	17	NUM
bjp-70889	230	4	:	:	SYM
bjp-70889	230	5	1	1	NUM
bjp-70889	230	6	-	-	SYM
bjp-70889	230	7	8	8	NUM
bjp-70889	230	8	.	.	PUNCT
bjp-70889	231	1	liu	liu	PROPN
bjp-70889	231	2	l	l	PROPN
bjp-70889	231	3	,	,	PUNCT
bjp-70889	231	4	fan	fan	PROPN
bjp-70889	231	5	j	j	PROPN
bjp-70889	231	6	,	,	PUNCT
bjp-70889	231	7	ai	ai	VERB
bjp-70889	231	8	g	g	PROPN
bjp-70889	231	9	,	,	PUNCT
bjp-70889	231	10	liu	liu	PROPN
bjp-70889	231	11	j	j	PROPN
bjp-70889	231	12	,	,	PUNCT
bjp-70889	231	13	luo	luo	PROPN
bjp-70889	231	14	n	n	PROPN
bjp-70889	231	15	,	,	PUNCT
bjp-70889	231	16	li	li	PROPN
bjp-70889	231	17	c	c	PROPN
bjp-70889	231	18	,	,	PUNCT
bjp-70889	231	19	cheng	cheng	PROPN
bjp-70889	231	20	z.	z.	PROPN
bjp-70889	231	21	berberine	berberine	PROPN
bjp-70889	231	22	in	in	ADP
bjp-70889	231	23	combination	combination	NOUN
bjp-70889	231	24	with	with	ADP
bjp-70889	231	25	cisplatin	cisplatin	NOUN
bjp-70889	231	26	induces	induce	NOUN
bjp-70889	231	27	necroptosis	necroptosis	NOUN
bjp-70889	231	28	and	and	CCONJ
bjp-70889	231	29	apoptosis	apoptosis	NOUN
bjp-70889	231	30	in	in	ADP
bjp-70889	231	31	ovarian	ovarian	ADJ
bjp-70889	231	32	cancer	cancer	NOUN
bjp-70889	231	33	cells	cell	NOUN
bjp-70889	231	34	.	.	PUNCT
bjp-70889	232	1	biol	biol	PROPN
bjp-70889	232	2	res	re	NOUN
bjp-70889	232	3	.	.	PROPN
bjp-70889	232	4	2019	2019	NUM
bjp-70889	232	5	;	;	PUNCT
bjp-70889	232	6	52	52	NUM
bjp-70889	232	7	:	:	SYM
bjp-70889	232	8	37	37	NUM
bjp-70889	232	9	.	.	PUNCT
bjp-70889	233	1	mahata	mahata	PROPN
bjp-70889	233	2	s	s	PROPN
bjp-70889	233	3	,	,	PUNCT
bjp-70889	233	4	bharti	bharti	PROPN
bjp-70889	233	5	ac	ac	PROPN
bjp-70889	233	6	,	,	PUNCT
bjp-70889	233	7	shukla	shukla	PROPN
bjp-70889	233	8	s	s	PROPN
bjp-70889	233	9	,	,	PUNCT
bjp-70889	233	10	tyagi	tyagi	PROPN
bjp-70889	233	11	a	a	PROPN
bjp-70889	233	12	,	,	PUNCT
bjp-70889	233	13	husain	husain	PROPN
bjp-70889	233	14	sa	sa	PROPN
bjp-70889	233	15	,	,	PUNCT
bjp-70889	233	16	das	das	PROPN
bjp-70889	233	17	bc	bc	PROPN
bjp-70889	233	18	.	.	PROPN
bjp-70889	233	19	berberine	berberine	PROPN
bjp-70889	233	20	modulates	modulate	NOUN
bjp-70889	233	21	ap-1	ap-1	ADP
bjp-70889	233	22	activity	activity	NOUN
bjp-70889	233	23	to	to	PART
bjp-70889	233	24	suppress	suppress	VERB
bjp-70889	233	25	hpv	hpv	NOUN
bjp-70889	233	26	transcription	transcription	NOUN
bjp-70889	233	27	and	and	CCONJ
bjp-70889	233	28	downstream	downstream	NOUN
bjp-70889	233	29	signaling	signal	VERB
bjp-70889	233	30	to	to	PART
bjp-70889	233	31	induce	induce	VERB
bjp-70889	233	32	growth	growth	NOUN
bjp-70889	233	33	arrest	arrest	NOUN
bjp-70889	233	34	and	and	CCONJ
bjp-70889	233	35	apoptosis	apoptosis	NOUN
bjp-70889	233	36	in	in	ADP
bjp-70889	233	37	cervical	cervical	ADJ
bjp-70889	233	38	cancer	cancer	NOUN
bjp-70889	233	39	cells	cell	NOUN
bjp-70889	233	40	.	.	PUNCT
bjp-70889	234	1	mol	mol	ADP
bjp-70889	234	2	cancer	cancer	NOUN
bjp-70889	234	3	.	.	PUNCT
bjp-70889	235	1	2011	2011	NUM
bjp-70889	235	2	;	;	PUNCT
bjp-70889	235	3	10	10	NUM
bjp-70889	235	4	:	:	SYM
bjp-70889	235	5	39	39	NUM
bjp-70889	235	6	.	.	PUNCT
bjp-70889	236	1	mantena	mantena	PROPN
bjp-70889	236	2	sk	sk	PROPN
bjp-70889	236	3	,	,	PUNCT
bjp-70889	236	4	sharma	sharma	PROPN
bjp-70889	236	5	sd	sd	PROPN
bjp-70889	236	6	,	,	PUNCT
bjp-70889	236	7	katiyar	katiyar	PROPN
bjp-70889	236	8	sk	sk	PROPN
bjp-70889	236	9	.	.	PROPN
bjp-70889	236	10	berberine	berberine	PROPN
bjp-70889	236	11	,	,	PUNCT
bjp-70889	236	12	a	a	DET
bjp-70889	236	13	natural	natural	ADJ
bjp-70889	236	14	product	product	NOUN
bjp-70889	236	15	,	,	PUNCT
bjp-70889	236	16	induces	induce	VERB
bjp-70889	236	17	g1	g1	ADJ
bjp-70889	236	18	-	-	PUNCT
bjp-70889	236	19	phase	phase	NOUN
bjp-70889	236	20	cell	cell	NOUN
bjp-70889	236	21	cycle	cycle	NOUN
bjp-70889	236	22	arrest	arrest	NOUN
bjp-70889	236	23	and	and	CCONJ
bjp-70889	236	24	caspase-3dependent	caspase-3dependent	NOUN
bjp-70889	236	25	apoptosis	apoptosis	NOUN
bjp-70889	236	26	in	in	ADP
bjp-70889	236	27	human	human	ADJ
bjp-70889	236	28	prostate	prostate	NOUN
bjp-70889	236	29	carcinoma	carcinoma	NOUN
bjp-70889	236	30	cells	cell	NOUN
bjp-70889	236	31	.	.	PUNCT
bjp-70889	237	1	mol	mol	ADP
bjp-70889	237	2	cancer	cancer	NOUN
bjp-70889	237	3	ther	ther	ADV
bjp-70889	237	4	.	.	PUNCT
bjp-70889	238	1	2006	2006	NUM
bjp-70889	238	2	;	;	PUNCT
bjp-70889	238	3	5	5	NUM
bjp-70889	238	4	:	:	SYM
bjp-70889	238	5	296	296	NUM
bjp-70889	238	6	-	-	SYM
bjp-70889	238	7	308	308	NUM
bjp-70889	238	8	.	.	PUNCT
bjp-70889	239	1	n	n	PROPN
bjp-70889	239	2	ke	ke	NOUN
bjp-70889	239	3	,	,	PUNCT
bjp-70889	239	4	koutras	koutras	PROPN
bjp-70889	239	5	a	a	PRON
bjp-70889	239	6	,	,	PUNCT
bjp-70889	239	7	syllaios	syllaio	VERB
bjp-70889	239	8	a	a	PRON
bjp-70889	239	9	,	,	PUNCT
bjp-70889	239	10	schizas	schizas	NOUN
bjp-70889	239	11	d	d	NOUN
bjp-70889	239	12	,	,	PUNCT
bjp-70889	239	13	kalagasidou	kalagasidou	PROPN
bjp-70889	239	14	s	s	PART
bjp-70889	239	15	,	,	PUNCT
bjp-70889	239	16	pagkalos	pagkalo	VERB
bjp-70889	239	17	a	a	PRON
bjp-70889	239	18	,	,	PUNCT
bjp-70889	239	19	alatzidou	alatzidou	PROPN
bjp-70889	239	20	d	d	NOUN
bjp-70889	239	21	,	,	PUNCT
bjp-70889	239	22	kantari	kantari	PROPN
bjp-70889	239	23	p	p	X
bjp-70889	239	24	,	,	PUNCT
bjp-70889	239	25	ntounis	ntounis	PROPN
bjp-70889	239	26	t	t	PROPN
bjp-70889	239	27	,	,	PUNCT
bjp-70889	239	28	fasoulakis	fasoulakis	PROPN
bjp-70889	239	29	z.	z.	PROPN
bjp-70889	239	30	basic	basic	ADJ
bjp-70889	239	31	principles	principle	NOUN
bjp-70889	239	32	of	of	ADP
bjp-70889	239	33	molecular	molecular	ADJ
bjp-70889	239	34	biology	biology	NOUN
bjp-70889	239	35	of	of	ADP
bjp-70889	239	36	cancer	cancer	NOUN
bjp-70889	239	37	cell	cell	NOUN
bjp-70889	239	38	:	:	PUNCT
bjp-70889	239	39	molecular	molecular	ADJ
bjp-70889	239	40	cancer	cancer	NOUN
bjp-70889	239	41	indicators	indicator	NOUN
bjp-70889	239	42	.	.	PUNCT
bjp-70889	240	1	j	j	PROPN
bjp-70889	240	2	buon	buon	NOUN
bjp-70889	240	3	.	.	PUNCT
bjp-70889	241	1	2021	2021	NUM
bjp-70889	241	2	;	;	PUNCT
bjp-70889	241	3	26	26	NUM
bjp-70889	241	4	:	:	SYM
bjp-70889	241	5	1723	1723	NUM
bjp-70889	241	6	-	-	SYM
bjp-70889	241	7	34	34	NUM
bjp-70889	241	8	.	.	PUNCT
bjp-70889	242	1	park	park	PROPN
bjp-70889	242	2	hh	hh	PROPN
bjp-70889	242	3	,	,	PUNCT
bjp-70889	242	4	kim	kim	PROPN
bjp-70889	242	5	hr	hr	PROPN
bjp-70889	242	6	,	,	PUNCT
bjp-70889	242	7	park	park	NOUN
bjp-70889	242	8	sy	sy	PROPN
bjp-70889	242	9	,	,	PUNCT
bjp-70889	242	10	hwang	hwang	PROPN
bjp-70889	242	11	sm	sm	PROPN
bjp-70889	242	12	,	,	PUNCT
bjp-70889	242	13	hong	hong	PROPN
bjp-70889	242	14	sm	sm	PROPN
bjp-70889	242	15	,	,	PUNCT
bjp-70889	242	16	park	park	NOUN
bjp-70889	242	17	s	s	PROPN
bjp-70889	242	18	,	,	PUNCT
bjp-70889	242	19	kang	kang	PROPN
bjp-70889	242	20	hc	hc	PROPN
bjp-70889	242	21	,	,	PUNCT
bjp-70889	242	22	morgan	morgan	PROPN
bjp-70889	242	23	mj	mj	PROPN
bjp-70889	242	24	,	,	PUNCT
bjp-70889	242	25	cha	cha	PROPN
bjp-70889	242	26	jh	jh	PROPN
bjp-70889	242	27	,	,	PUNCT
bjp-70889	242	28	lee	lee	PROPN
bjp-70889	243	1	d	d	PROPN
bjp-70889	243	2	,	,	PUNCT
bjp-70889	243	3	roe	roe	PROPN
bjp-70889	243	4	js	js	PROPN
bjp-70889	243	5	,	,	PUNCT
bjp-70889	243	6	kim	kim	PROPN
bjp-70889	243	7	ys	ys	PROPN
bjp-70889	243	8	.	.	PUNCT
bjp-70889	244	1	ripk3	ripk3	NOUN
bjp-70889	244	2	activation	activation	NOUN
bjp-70889	244	3	induces	induce	VERB
bjp-70889	244	4	trim28	trim28	NOUN
bjp-70889	244	5	derepression	derepression	PROPN
bjp-70889	244	6	in	in	ADP
bjp-70889	244	7	cancer	cancer	NOUN
bjp-70889	244	8	cells	cell	NOUN
bjp-70889	244	9	and	and	CCONJ
bjp-70889	244	10	enhances	enhance	VERB
bjp-70889	244	11	the	the	DET
bjp-70889	244	12	anti	anti	ADJ
bjp-70889	244	13	-	-	ADJ
bjp-70889	244	14	tumor	tumor	ADJ
bjp-70889	244	15	microenvironment	microenvironment	NOUN
bjp-70889	244	16	.	.	PUNCT
bjp-70889	245	1	mol	mol	ADP
bjp-70889	245	2	cancer	cancer	NOUN
bjp-70889	245	3	.	.	PUNCT
bjp-70889	245	4	2021	2021	NUM
bjp-70889	245	5	;	;	PUNCT
bjp-70889	245	6	20	20	NUM
bjp-70889	245	7	:	:	SYM
bjp-70889	245	8	107	107	NUM
bjp-70889	245	9	.	.	PUNCT
bjp-70889	245	10	park	park	PROPN
bjp-70889	245	11	sy	sy	PROPN
bjp-70889	245	12	,	,	PUNCT
bjp-70889	245	13	park	park	NOUN
bjp-70889	245	14	hh	hh	PROPN
bjp-70889	245	15	,	,	PUNCT
bjp-70889	245	16	park	park	NOUN
bjp-70889	245	17	sy	sy	PROPN
bjp-70889	245	18	,	,	PUNCT
bjp-70889	245	19	hong	hong	PROPN
bjp-70889	245	20	sm	sm	PROPN
bjp-70889	245	21	,	,	PUNCT
bjp-70889	245	22	yoon	yoon	PROPN
bjp-70889	245	23	s	s	PROPN
bjp-70889	245	24	,	,	PUNCT
bjp-70889	245	25	morgan	morgan	PROPN
bjp-70889	245	26	mj	mj	PROPN
bjp-70889	245	27	,	,	PUNCT
bjp-70889	245	28	kim	kim	PROPN
bjp-70889	245	29	ys	ys	PROPN
bjp-70889	245	30	.	.	PUNCT
bjp-70889	245	31	reduction	reduction	NOUN
bjp-70889	245	32	in	in	ADP
bjp-70889	245	33	mlkl	mlkl	ADV
bjp-70889	245	34	-	-	PUNCT
bjp-70889	245	35	mediated	mediate	VERB
bjp-70889	245	36	endosomal	endosomal	ADJ
bjp-70889	245	37	trafficking	trafficking	NOUN
bjp-70889	245	38	enhances	enhance	VERB
bjp-70889	245	39	the	the	DET
bjp-70889	245	40	trail	trail	NOUN
bjp-70889	245	41	-	-	PUNCT
bjp-70889	245	42	dr4/5	dr4/5	NOUN
bjp-70889	245	43	signal	signal	NOUN
bjp-70889	245	44	to	to	PART
bjp-70889	245	45	increase	increase	VERB
bjp-70889	245	46	cancer	cancer	NOUN
bjp-70889	245	47	cell	cell	NOUN
bjp-70889	245	48	death	death	NOUN
bjp-70889	245	49	.	.	PUNCT
bjp-70889	246	1	cell	cell	NOUN
bjp-70889	246	2	death	death	NOUN
bjp-70889	246	3	dis	dis	PROPN
bjp-70889	246	4	.	.	PUNCT
bjp-70889	247	1	2020	2020	NUM
bjp-70889	247	2	;	;	PUNCT
bjp-70889	247	3	11	11	NUM
bjp-70889	247	4	:	:	SYM
bjp-70889	247	5	744	744	NUM
bjp-70889	247	6	.	.	X
bjp-70889	248	1	ruan	ruan	PROPN
bjp-70889	248	2	j	j	PROPN
bjp-70889	248	3	,	,	PUNCT
bjp-70889	248	4	mei	mei	PROPN
bjp-70889	248	5	l	l	PROPN
bjp-70889	248	6	,	,	PUNCT
bjp-70889	248	7	zhu	zhu	PROPN
bjp-70889	248	8	q	q	X
bjp-70889	248	9	,	,	PUNCT
bjp-70889	248	10	shi	shi	PROPN
bjp-70889	248	11	g	g	PROPN
bjp-70889	248	12	,	,	PUNCT
bjp-70889	248	13	wang	wang	PROPN
bjp-70889	248	14	h.	h.	PROPN
bjp-70889	248	15	mixed	mixed	PROPN
bjp-70889	248	16	lineage	lineage	PROPN
bjp-70889	248	17	kinase	kinase	NOUN
bjp-70889	248	18	domain	domain	NOUN
bjp-70889	248	19	-	-	PUNCT
bjp-70889	248	20	like	like	ADJ
bjp-70889	248	21	protein	protein	NOUN
bjp-70889	248	22	is	be	AUX
bjp-70889	248	23	a	a	DET
bjp-70889	248	24	prognostic	prognostic	ADJ
bjp-70889	248	25	biomarker	biomarker	NOUN
bjp-70889	248	26	for	for	ADP
bjp-70889	248	27	cervical	cervical	ADJ
bjp-70889	248	28	squamous	squamous	ADJ
bjp-70889	248	29	cell	cell	NOUN
bjp-70889	248	30	cancer	cancer	NOUN
bjp-70889	248	31	.	.	PUNCT
bjp-70889	249	1	int	int	PROPN
bjp-70889	250	1	j	j	PROPN
bjp-70889	250	2	clin	clin	PROPN
bjp-70889	250	3	exp	exp	NOUN
bjp-70889	250	4	pathol	pathol	NOUN
bjp-70889	250	5	.	.	PUNCT
bjp-70889	251	1	2015	2015	NUM
bjp-70889	251	2	;	;	PUNCT
bjp-70889	251	3	8	8	NUM
bjp-70889	251	4	:	:	SYM
bjp-70889	251	5	1503538	1503538	NUM
bjp-70889	251	6	.	.	PUNCT
bjp-70889	252	1	rui	rui	PROPN
bjp-70889	252	2	z	z	PROPN
bjp-70889	252	3	,	,	PUNCT
bjp-70889	252	4	chang	chang	PROPN
bjp-70889	252	5	-	-	PUNCT
bjp-70889	252	6	pei	pei	PROPN
bjp-70889	252	7	x	x	PROPN
bjp-70889	252	8	,	,	PUNCT
bjp-70889	252	9	jing	je	VERB
bjp-70889	252	10	-	-	PUNCT
bjp-70889	252	11	jing	jing	PROPN
bjp-70889	252	12	z	z	PROPN
bjp-70889	252	13	,	,	PUNCT
bjp-70889	252	14	hong	hong	PROPN
bjp-70889	252	15	-	-	PUNCT
bjp-70889	252	16	jun	jun	PROPN
bjp-70889	252	17	y.	y.	PROPN
bjp-70889	253	1	[	[	X
bjp-70889	253	2	research	research	NOUN
bjp-70889	253	3	progress	progress	NOUN
bjp-70889	253	4	on	on	ADP
bjp-70889	253	5	chemical	chemical	ADJ
bjp-70889	253	6	compositions	composition	NOUN
bjp-70889	253	7	of	of	ADP
bjp-70889	253	8	coptidis	coptidis	PROPN
bjp-70889	253	9	rhizoma	rhizoma	ADJ
bjp-70889	253	10	and	and	CCONJ
bjp-70889	253	11	pharmacological	pharmacological	ADJ
bjp-70889	253	12	effects	effect	NOUN
bjp-70889	253	13	of	of	ADP
bjp-70889	253	14	berberine	berberine	NOUN
bjp-70889	253	15	]	]	PUNCT
bjp-70889	253	16	.	.	PUNCT
bjp-70889	254	1	zhongguo	zhongguo	PROPN
bjp-70889	254	2	zhong	zhong	PROPN
bjp-70889	254	3	yao	yao	PROPN
bjp-70889	254	4	za	za	PROPN
bjp-70889	254	5	zhi	zhi	PROPN
bjp-70889	254	6	.	.	PUNCT
bjp-70889	254	7	2020	2020	NUM
bjp-70889	254	8	;	;	PUNCT
bjp-70889	254	9	45	45	NUM
bjp-70889	254	10	:	:	SYM
bjp-70889	254	11	4561	4561	NUM
bjp-70889	254	12	-	-	SYM
bjp-70889	254	13	73	73	NUM
bjp-70889	254	14	.	.	PUNCT
bjp-70889	255	1	sawai	sawai	PROPN
bjp-70889	255	2	h.	h.	PROPN
bjp-70889	255	3	induction	induction	NOUN
bjp-70889	255	4	of	of	ADP
bjp-70889	255	5	apoptosis	apoptosis	NOUN
bjp-70889	255	6	in	in	ADP
bjp-70889	255	7	tnf	tnf	PROPN
bjp-70889	255	8	-	-	PUNCT
bjp-70889	255	9	treated	treat	VERB
bjp-70889	255	10	l929	l929	PROPN
bjp-70889	255	11	cells	cell	NOUN
bjp-70889	255	12	in	in	ADP
bjp-70889	255	13	the	the	DET
bjp-70889	255	14	presence	presence	NOUN
bjp-70889	255	15	of	of	ADP
bjp-70889	255	16	necrostatin-1	necrostatin-1	NUM
bjp-70889	255	17	.	.	PUNCT
bjp-70889	256	1	int	int	PROPN
bjp-70889	256	2	j	j	PROPN
bjp-70889	256	3	mol	mol	ADP
bjp-70889	256	4	sci	sci	PROPN
bjp-70889	256	5	.	.	PROPN
bjp-70889	256	6	2016	2016	NUM
bjp-70889	256	7	;	;	PUNCT
bjp-70889	256	8	17	17	NUM
bjp-70889	256	9	:	:	SYM
bjp-70889	256	10	1678	1678	NUM
bjp-70889	256	11	.	.	PUNCT
bjp-70889	257	1	shahsavari	shahsavari	PROPN
bjp-70889	257	2	z	z	PROPN
bjp-70889	257	3	,	,	PUNCT
bjp-70889	257	4	karami	karami	NOUN
bjp-70889	257	5	-	-	PUNCT
bjp-70889	257	6	tehrani	tehrani	NOUN
bjp-70889	257	7	f	f	PROPN
bjp-70889	257	8	,	,	PUNCT
bjp-70889	257	9	salami	salami	PROPN
bjp-70889	257	10	s	s	PROPN
bjp-70889	257	11	,	,	PUNCT
bjp-70889	257	12	ghasemzadeh	ghasemzadeh	PROPN
bjp-70889	257	13	m.	m.	PROPN
bjp-70889	257	14	rip1k	rip1k	PROPN
bjp-70889	257	15	and	and	CCONJ
bjp-70889	257	16	rip3k	rip3k	VERB
bjp-70889	257	17	provoked	provoke	VERB
bjp-70889	257	18	by	by	ADP
bjp-70889	257	19	shikonin	shikonin	ADJ
bjp-70889	257	20	induce	induce	VERB
bjp-70889	257	21	cell	cell	NOUN
bjp-70889	257	22	cycle	cycle	NOUN
bjp-70889	257	23	arrest	arrest	NOUN
bjp-70889	257	24	in	in	ADP
bjp-70889	257	25	the	the	DET
bjp-70889	257	26	triple	triple	ADJ
bjp-70889	257	27	negative	negative	ADJ
bjp-70889	257	28	breast	breast	NOUN
bjp-70889	257	29	cancer	cancer	NOUN
bjp-70889	257	30	cell	cell	NOUN
bjp-70889	257	31	line	line	NOUN
bjp-70889	257	32	,	,	PUNCT
bjp-70889	257	33	mda	mda	PROPN
bjp-70889	257	34	-	-	PUNCT
bjp-70889	257	35	mb468	mb468	PROPN
bjp-70889	257	36	:	:	PUNCT
bjp-70889	257	37	necroptosis	necroptosis	NOUN
bjp-70889	257	38	as	as	ADP
bjp-70889	257	39	a	a	DET
bjp-70889	257	40	desperate	desperate	ADJ
bjp-70889	257	41	programmed	programmed	ADJ
bjp-70889	257	42	suicide	suicide	NOUN
bjp-70889	257	43	pathway	pathway	NOUN
bjp-70889	257	44	.	.	PUNCT
bjp-70889	258	1	tumour	tumour	PROPN
bjp-70889	258	2	biol	biol	PROPN
bjp-70889	258	3	.	.	PUNCT
bjp-70889	259	1	2016	2016	NUM
bjp-70889	259	2	;	;	PUNCT
bjp-70889	259	3	37	37	NUM
bjp-70889	259	4	:	:	SYM
bjp-70889	259	5	4479	4479	NUM
bjp-70889	259	6	-	-	SYM
bjp-70889	259	7	91	91	NUM
bjp-70889	259	8	.	.	PUNCT
bjp-70889	260	1	song	song	PROPN
bjp-70889	260	2	bb	bb	PROPN
bjp-70889	260	3	,	,	PUNCT
bjp-70889	260	4	xu	xu	PROPN
bjp-70889	261	1	my	my	PRON
bjp-70889	261	2	,	,	PUNCT
bjp-70889	261	3	xu	xu	PROPN
bjp-70889	261	4	xf	xf	PROPN
bjp-70889	261	5	,	,	PUNCT
bjp-70889	261	6	li	li	PROPN
bjp-70889	261	7	x	x	PROPN
bjp-70889	261	8	,	,	PUNCT
bjp-70889	261	9	chen	chen	PROPN
bjp-70889	261	10	m.	m.	PROPN
bjp-70889	261	11	zoledronic	zoledronic	PROPN
bjp-70889	261	12	acid	acid	PROPN
bjp-70889	261	13	inhibits	inhibit	VERB
bjp-70889	261	14	the	the	DET
bjp-70889	261	15	bone	bone	NOUN
bjp-70889	261	16	metastasis	metastasis	NOUN
bjp-70889	261	17	of	of	ADP
bjp-70889	261	18	breast	breast	NOUN
bjp-70889	261	19	cancer	cancer	NOUN
bjp-70889	261	20	by	by	ADP
bjp-70889	261	21	repressing	repress	VERB
bjp-70889	261	22	exosome	exosome	NOUN
bjp-70889	261	23	-	-	PUNCT
bjp-70889	261	24	loaded	load	VERB
bjp-70889	261	25	dkk1	dkk1	PROPN
bjp-70889	261	26	.	.	PUNCT
bjp-70889	262	1	bangladesh	bangladesh	PROPN
bjp-70889	262	2	j	j	PROPN
bjp-70889	262	3	pharmacol	pharmacol	PROPN
bjp-70889	262	4	.	.	PUNCT
bjp-70889	263	1	2022	2022	NUM
bjp-70889	263	2	;	;	PUNCT
bjp-70889	263	3	17	17	NUM
bjp-70889	263	4	:	:	SYM
bjp-70889	263	5	92	92	NUM
bjp-70889	263	6	-	-	SYM
bjp-70889	263	7	101	101	NUM
bjp-70889	263	8	.	.	PUNCT
bjp-70889	264	1	sun	sun	PROPN
bjp-70889	264	2	w	w	PROPN
bjp-70889	264	3	,	,	PUNCT
bjp-70889	264	4	yu	yu	PROPN
bjp-70889	264	5	w	w	PROPN
bjp-70889	264	6	,	,	PUNCT
bjp-70889	264	7	shen	shen	PROPN
bjp-70889	264	8	l	l	PROPN
bjp-70889	264	9	,	,	PUNCT
bjp-70889	264	10	huang	huang	PROPN
bjp-70889	264	11	t.	t.	PROPN
bjp-70889	264	12	mlkl	mlkl	PROPN
bjp-70889	264	13	is	be	AUX
bjp-70889	264	14	a	a	DET
bjp-70889	264	15	potential	potential	ADJ
bjp-70889	264	16	prognostic	prognostic	ADJ
bjp-70889	264	17	marker	marker	NOUN
bjp-70889	264	18	in	in	ADP
bjp-70889	264	19	gastric	gastric	ADJ
bjp-70889	264	20	cancer	cancer	NOUN
bjp-70889	264	21	.	.	PUNCT
bjp-70889	265	1	oncol	oncol	ADJ
bjp-70889	265	2	lett	lett	PROPN
bjp-70889	265	3	.	.	PROPN
bjp-70889	266	1	2019	2019	NUM
bjp-70889	266	2	;	;	PUNCT
bjp-70889	266	3	18	18	NUM
bjp-70889	266	4	:	:	SYM
bjp-70889	266	5	3830	3830	NUM
bjp-70889	266	6	-	-	SYM
bjp-70889	266	7	36	36	NUM
bjp-70889	266	8	.	.	PUNCT
bjp-70889	266	9	trope	trope	NOUN
bjp-70889	266	10	a	a	DET
bjp-70889	266	11	,	,	PUNCT
bjp-70889	266	12	sjoborg	sjoborg	PROPN
bjp-70889	266	13	k	k	NOUN
bjp-70889	266	14	,	,	PUNCT
bjp-70889	266	15	eskild	eskild	VERB
bjp-70889	266	16	a	a	DET
bjp-70889	266	17	,	,	PUNCT
bjp-70889	266	18	cuschieri	cuschieri	PROPN
bjp-70889	266	19	k	k	PROPN
bjp-70889	266	20	,	,	PUNCT
bjp-70889	266	21	eriksen	eriksen	PROPN
bjp-70889	266	22	t	t	PROPN
bjp-70889	266	23	,	,	PUNCT
bjp-70889	266	24	thoresen	thoresen	PROPN
bjp-70889	266	25	s	s	PROPN
bjp-70889	266	26	,	,	PUNCT
bjp-70889	266	27	et	et	PROPN
bjp-70889	266	28	al	al	PROPN
bjp-70889	266	29	.	.	PUNCT
bjp-70889	266	30	performance	performance	NOUN
bjp-70889	266	31	of	of	ADP
bjp-70889	266	32	human	human	ADJ
bjp-70889	266	33	papillomavirus	papillomavirus	NOUN
bjp-70889	266	34	dna	dna	PROPN
bjp-70889	266	35	and	and	CCONJ
bjp-70889	266	36	mrna	mrna	PROPN
bjp-70889	266	37	testing	testing	NOUN
bjp-70889	266	38	strategies	strategy	NOUN
bjp-70889	266	39	for	for	ADP
bjp-70889	266	40	women	woman	NOUN
bjp-70889	266	41	with	with	ADP
bjp-70889	266	42	and	and	CCONJ
bjp-70889	266	43	without	without	ADP
bjp-70889	266	44	cervical	cervical	ADJ
bjp-70889	266	45	neoplasia	neoplasia	NOUN
bjp-70889	266	46	.	.	PUNCT
bjp-70889	267	1	j	j	PROPN
bjp-70889	267	2	clin	clin	PROPN
bjp-70889	267	3	microbiol	microbiol	PROPN
bjp-70889	267	4	.	.	PUNCT
bjp-70889	268	1	2009	2009	NUM
bjp-70889	268	2	;	;	PUNCT
bjp-70889	268	3	47	47	NUM
bjp-70889	268	4	:	:	SYM
bjp-70889	268	5	2458	2458	NUM
bjp-70889	268	6	-	-	SYM
bjp-70889	268	7	64	64	NUM
bjp-70889	268	8	.	.	PUNCT
bjp-70889	269	1	vanden	vanden	PROPN
bjp-70889	269	2	bt	bt	PROPN
bjp-70889	269	3	,	,	PUNCT
bjp-70889	269	4	linkermann	linkermann	VERB
bjp-70889	269	5	a	a	DET
bjp-70889	269	6	,	,	PUNCT
bjp-70889	269	7	jouan	jouan	ADJ
bjp-70889	269	8	-	-	PUNCT
bjp-70889	269	9	lanhouet	lanhouet	NOUN
bjp-70889	269	10	s	s	NOUN
bjp-70889	269	11	,	,	PUNCT
bjp-70889	269	12	walczak	walczak	ADJ
bjp-70889	269	13	h	h	NOUN
bjp-70889	269	14	,	,	PUNCT
bjp-70889	269	15	vandenabeele	vandenabeele	PROPN
bjp-70889	269	16	p.	p.	NOUN
bjp-70889	269	17	regulated	regulate	VERB
bjp-70889	269	18	necrosis	necrosis	NOUN
bjp-70889	269	19	:	:	PUNCT
bjp-70889	269	20	the	the	DET
bjp-70889	269	21	expanding	expand	VERB
bjp-70889	269	22	network	network	NOUN
bjp-70889	269	23	of	of	ADP
bjp-70889	269	24	non	non	ADJ
bjp-70889	269	25	-	-	ADJ
bjp-70889	269	26	apoptotic	apoptotic	ADJ
bjp-70889	269	27	cell	cell	NOUN
bjp-70889	269	28	death	death	NOUN
bjp-70889	269	29	pathways	pathway	NOUN
bjp-70889	269	30	.	.	PUNCT
bjp-70889	270	1	nat	nat	PROPN
bjp-70889	270	2	rev	rev	VERB
bjp-70889	270	3	mol	mol	ADP
bjp-70889	270	4	cell	cell	NOUN
bjp-70889	270	5	biol	biol	NOUN
bjp-70889	270	6	.	.	PUNCT
bjp-70889	271	1	2014	2014	NUM
bjp-70889	271	2	;	;	PUNCT
bjp-70889	271	3	15	15	NUM
bjp-70889	271	4	:	:	SYM
bjp-70889	271	5	135	135	NUM
bjp-70889	271	6	-	-	SYM
bjp-70889	271	7	47	47	NUM
bjp-70889	271	8	.	.	PUNCT
bjp-70889	272	1	verdonck	verdonck	PROPN
bjp-70889	272	2	s	s	PROPN
bjp-70889	272	3	,	,	PUNCT
bjp-70889	272	4	nemegeer	nemegeer	NOUN
bjp-70889	272	5	j	j	PROPN
bjp-70889	272	6	,	,	PUNCT
bjp-70889	272	7	vandenabeele	vandenabeele	NOUN
bjp-70889	272	8	p	p	NOUN
bjp-70889	272	9	,	,	PUNCT
bjp-70889	272	10	maelfait	maelfait	NOUN
bjp-70889	272	11	j.	j.	PROPN
bjp-70889	272	12	viral	viral	ADJ
bjp-70889	272	13	manipulation	manipulation	NOUN
bjp-70889	272	14	of	of	ADP
bjp-70889	272	15	host	host	NOUN
bjp-70889	272	16	cell	cell	NOUN
bjp-70889	272	17	necroptosis	necroptosis	NOUN
bjp-70889	272	18	and	and	CCONJ
bjp-70889	272	19	pyroptosis	pyroptosis	NOUN
bjp-70889	272	20	.	.	PUNCT
bjp-70889	273	1	trends	trend	NOUN
bjp-70889	273	2	microbiol	microbiol	PROPN
bjp-70889	273	3	.	.	PUNCT
bjp-70889	274	1	2022	2022	NUM
bjp-70889	274	2	;	;	PUNCT
bjp-70889	274	3	30	30	NUM
bjp-70889	274	4	:	:	PUNCT
bjp-70889	274	5	593	593	NUM
bjp-70889	274	6	-	-	SYM
bjp-70889	274	7	605	605	NUM
bjp-70889	274	8	.	.	PUNCT
bjp-70889	275	1	warowicka	warowicka	VERB
bjp-70889	275	2	a	a	PRON
bjp-70889	275	3	,	,	PUNCT
bjp-70889	275	4	nawrot	nawrot	ADJ
bjp-70889	275	5	r	r	NOUN
bjp-70889	275	6	,	,	PUNCT
bjp-70889	275	7	gozdzicka	gozdzicka	NOUN
bjp-70889	275	8	-	-	PUNCT
bjp-70889	275	9	jozefiak	jozefiak	PROPN
bjp-70889	275	10	a.	a.	PROPN
bjp-70889	275	11	antiviral	antiviral	PROPN
bjp-70889	275	12	activity	activity	NOUN
bjp-70889	275	13	of	of	ADP
bjp-70889	275	14	berberine	berberine	NOUN
bjp-70889	275	15	.	.	PUNCT
bjp-70889	276	1	arch	arch	ADJ
bjp-70889	276	2	virol	virol	NOUN
bjp-70889	276	3	.	.	PUNCT
bjp-70889	277	1	2020	2020	NUM
bjp-70889	277	2	;	;	PUNCT
bjp-70889	277	3	165	165	NUM
bjp-70889	277	4	:	:	SYM
bjp-70889	277	5	1935	1935	NUM
bjp-70889	277	6	-	-	SYM
bjp-70889	277	7	45	45	NUM
bjp-70889	277	8	.	.	PUNCT
bjp-70889	278	1	bangladesh	bangladesh	PROPN
bjp-70889	278	2	j	j	PROPN
bjp-70889	278	3	pharmacol	pharmacol	PROPN
bjp-70889	278	4	2024	2024	NUM
bjp-70889	278	5	;	;	PUNCT
bjp-70889	278	6	19	19	NUM
bjp-70889	278	7	:	:	SYM
bjp-70889	278	8	13	13	NUM
bjp-70889	278	9	-	-	SYM
bjp-70889	278	10	22	22	NUM
bjp-70889	278	11	21	21	NUM
bjp-70889	278	12	author	author	NOUN
bjp-70889	278	13	info	info	NOUN
bjp-70889	278	14	yuzhen	yuzhen	PROPN
bjp-70889	278	15	zhou	zhou	PROPN
bjp-70889	278	16	and	and	CCONJ
bjp-70889	278	17	yan	yan	PROPN
bjp-70889	278	18	huang	huang	PROPN
bjp-70889	278	19	(	(	PUNCT
bjp-70889	278	20	principal	principal	ADJ
bjp-70889	278	21	contact	contact	NOUN
bjp-70889	278	22	)	)	PUNCT
bjp-70889	279	1	e	e	NOUN
bjp-70889	279	2	-	-	NOUN
bjp-70889	279	3	mail	mail	NOUN
bjp-70889	279	4	:	:	PUNCT
bjp-70889	279	5	zhouyuzhen100@sina.com	zhouyuzhen100@sina.com	NOUN
bjp-70889	279	6	;	;	PUNCT
bjp-70889	279	7	1771479075@qq.com	1771479075@qq.com	NUM
bjp-70889	279	8	first	first	ADJ
bjp-70889	279	9	three	three	NUM
bjp-70889	279	10	authors	author	NOUN
bjp-70889	279	11	contributed	contribute	VERB
bjp-70889	279	12	same	same	ADJ
bjp-70889	279	13	in	in	ADP
bjp-70889	279	14	this	this	DET
bjp-70889	279	15	work	work	NOUN
bjp-70889	279	16	zhang	zhang	PROPN
bjp-70889	279	17	g	g	PROPN
bjp-70889	279	18	,	,	PUNCT
bjp-70889	279	19	wang	wang	PROPN
bjp-70889	279	20	j	j	PROPN
bjp-70889	279	21	,	,	PUNCT
bjp-70889	279	22	zhao	zhao	PROPN
bjp-70889	279	23	z	z	PROPN
bjp-70889	279	24	,	,	PUNCT
bjp-70889	279	25	xin	xin	PROPN
bjp-70889	279	26	t	t	PROPN
bjp-70889	279	27	,	,	PUNCT
bjp-70889	279	28	fan	fan	NOUN
bjp-70889	279	29	x	x	PROPN
bjp-70889	279	30	,	,	PUNCT
bjp-70889	279	31	shen	shen	PROPN
bjp-70889	279	32	q	q	X
bjp-70889	279	33	,	,	PUNCT
bjp-70889	279	34	raheem	raheem	PROPN
bjp-70889	279	35	a	a	PRON
bjp-70889	279	36	,	,	PUNCT
bjp-70889	279	37	lee	lee	PROPN
bjp-70889	279	38	cr	cr	PROPN
bjp-70889	279	39	,	,	PUNCT
bjp-70889	279	40	jiang	jiang	PROPN
bjp-70889	279	41	h	h	PROPN
bjp-70889	279	42	,	,	PUNCT
bjp-70889	279	43	ding	ding	PROPN
bjp-70889	279	44	j.	j.	PROPN
bjp-70889	279	45	regulated	regulated	ADJ
bjp-70889	279	46	necrosis	necrosis	NOUN
bjp-70889	279	47	,	,	PUNCT
bjp-70889	279	48	a	a	DET
bjp-70889	279	49	proinflammatory	proinflammatory	ADJ
bjp-70889	279	50	cell	cell	NOUN
bjp-70889	279	51	death	death	NOUN
bjp-70889	279	52	,	,	PUNCT
bjp-70889	279	53	potentially	potentially	ADV
bjp-70889	279	54	counteracts	counteract	VERB
bjp-70889	279	55	pathogenic	pathogenic	ADJ
bjp-70889	279	56	infections	infection	NOUN
bjp-70889	279	57	.	.	PUNCT
bjp-70889	280	1	cell	cell	NOUN
bjp-70889	280	2	death	death	NOUN
bjp-70889	280	3	dis	dis	PROPN
bjp-70889	280	4	.	.	PUNCT
bjp-70889	281	1	2022	2022	NUM
bjp-70889	281	2	;	;	PUNCT
bjp-70889	281	3	13	13	NUM
bjp-70889	281	4	:	:	SYM
bjp-70889	281	5	637	637	NUM
bjp-70889	281	6	.	.	PUNCT
bjp-70889	282	1	zhu	zhu	PROPN
bjp-70889	282	2	m	m	PROPN
bjp-70889	282	3	,	,	PUNCT
bjp-70889	282	4	he	he	PRON
bjp-70889	282	5	y	y	NOUN
bjp-70889	282	6	,	,	PUNCT
bjp-70889	282	7	baak	baak	ADJ
bjp-70889	282	8	jp	jp	NOUN
bjp-70889	282	9	,	,	PUNCT
bjp-70889	282	10	zhou	zhou	PROPN
bjp-70889	282	11	x	x	PROPN
bjp-70889	282	12	,	,	PUNCT
bjp-70889	282	13	qu	qu	PROPN
bjp-70889	282	14	y	y	PROPN
bjp-70889	282	15	,	,	PUNCT
bjp-70889	282	16	sui	sui	PROPN
bjp-70889	282	17	l	l	PROPN
bjp-70889	282	18	,	,	PUNCT
bjp-70889	282	19	feng	feng	PROPN
bjp-70889	282	20	w	w	PROPN
bjp-70889	282	21	,	,	PUNCT
bjp-70889	282	22	wang	wang	PROPN
bjp-70889	282	23	q.	q.	PROPN
bjp-70889	282	24	factors	factor	NOUN
bjp-70889	282	25	that	that	PRON
bjp-70889	282	26	influence	influence	VERB
bjp-70889	282	27	persistence	persistence	NOUN
bjp-70889	282	28	or	or	CCONJ
bjp-70889	282	29	recurrence	recurrence	NOUN
bjp-70889	282	30	of	of	ADP
bjp-70889	282	31	highgrade	highgrade	NOUN
bjp-70889	282	32	squamous	squamous	ADJ
bjp-70889	282	33	intraepithelial	intraepithelial	ADJ
bjp-70889	282	34	lesion	lesion	NOUN
bjp-70889	282	35	with	with	ADP
bjp-70889	282	36	positive	positive	ADJ
bjp-70889	282	37	margins	margin	NOUN
bjp-70889	282	38	after	after	ADP
bjp-70889	282	39	the	the	DET
bjp-70889	282	40	loop	loop	NOUN
bjp-70889	282	41	electrosurgical	electrosurgical	ADJ
bjp-70889	282	42	excision	excision	NOUN
bjp-70889	282	43	procedure	procedure	NOUN
bjp-70889	282	44	:	:	PUNCT
bjp-70889	282	45	a	a	DET
bjp-70889	282	46	retrospective	retrospective	ADJ
bjp-70889	282	47	study	study	NOUN
bjp-70889	282	48	.	.	PUNCT
bjp-70889	283	1	bmc	bmc	ADJ
bjp-70889	283	2	cancer	cancer	NOUN
bjp-70889	283	3	.	.	PUNCT
bjp-70889	284	1	2015	2015	NUM
bjp-70889	284	2	;	;	PUNCT
bjp-70889	284	3	15	15	NUM
bjp-70889	285	1	:	:	SYM
bjp-70889	285	2	744	744	NUM
bjp-70889	285	3	.	.	NOUN
bjp-70889	285	4	22	22	NUM
bjp-70889	285	5	bangladesh	bangladesh	PROPN
bjp-70889	285	6	j	j	PROPN
bjp-70889	285	7	pharmacol	pharmacol	PROPN
bjp-70889	285	8	2024	2024	NUM
bjp-70889	285	9	;	;	PUNCT
bjp-70889	285	10	19	19	NUM
bjp-70889	285	11	:	:	SYM
bjp-70889	285	12	13	13	NUM
bjp-70889	285	13	-	-	SYM
bjp-70889	285	14	22	22	NUM
bjp-70889	285	15	mailto:zhouyuzhen100@sina.com	mailto:zhouyuzhen100@sina.com	X