id	sid	tid	token	lemma	pos
bjp-81605	1	1	bangladesh	bangladesh	PROPN
bjp-81605	1	2	journal	journal	PROPN
bjp-81605	1	3	of	of	ADP
bjp-81605	1	4	pharmacology	pharmacology	NOUN
bjp-81605	1	5	research	research	NOUN
bjp-81605	1	6	article	article	NOUN
bjp-81605	1	7	novel	novel	NOUN
bjp-81605	1	8	crt2	crt2	PROPN
bjp-81605	1	9	peptide	peptide	NOUN
bjp-81605	1	10	inhibits	inhibit	VERB
bjp-81605	1	11	tumor	tumor	NOUN
bjp-81605	1	12	growth	growth	NOUN
bjp-81605	1	13	and	and	CCONJ
bjp-81605	1	14	angiogenesis	angiogenesis	NOUN
bjp-81605	1	15	in	in	ADP
bjp-81605	1	16	colorectal	colorectal	ADJ
bjp-81605	1	17	cancer	cancer	NOUN
bjp-81605	1	18	ht-116	ht-116	NOUN
bjp-81605	1	19	cell	cell	NOUN
bjp-81605	1	20	lines	line	NOUN
bjp-81605	1	21	via	via	ADP
bjp-81605	1	22	pi3k	pi3k	PROPN
bjp-81605	1	23	/	/	SYM
bjp-81605	1	24	erk	erk	NOUN
bjp-81605	1	25	signaling	signal	VERB
bjp-81605	1	26	pathway	pathway	NOUN
bjp-81605	1	27	bjp	bjp	NOUN
bjp-81605	1	28	introduction	introduction	NOUN
bjp-81605	1	29	colorectal	colorectal	ADJ
bjp-81605	1	30	cancer	cancer	NOUN
bjp-81605	1	31	is	be	AUX
bjp-81605	1	32	characterized	characterize	VERB
bjp-81605	1	33	by	by	ADP
bjp-81605	1	34	genetic	genetic	ADJ
bjp-81605	1	35	abnormalities	abnormality	NOUN
bjp-81605	1	36	that	that	PRON
bjp-81605	1	37	lead	lead	VERB
bjp-81605	1	38	to	to	ADP
bjp-81605	1	39	uncontrolled	uncontrolled	ADJ
bjp-81605	1	40	cell	cell	NOUN
bjp-81605	1	41	proliferation	proliferation	NOUN
bjp-81605	1	42	in	in	ADP
bjp-81605	1	43	the	the	DET
bjp-81605	1	44	colorectal	colorectal	ADJ
bjp-81605	1	45	region	region	NOUN
bjp-81605	1	46	(	(	PUNCT
bjp-81605	1	47	baidoun	baidoun	NOUN
bjp-81605	1	48	,	,	PUNCT
bjp-81605	1	49	2021	2021	NUM
bjp-81605	1	50	;	;	PUNCT
bjp-81605	1	51	weitz	weitz	PROPN
bjp-81605	1	52	et	et	PROPN
bjp-81605	1	53	al	al	PROPN
bjp-81605	1	54	.	.	PROPN
bjp-81605	1	55	,	,	PUNCT
bjp-81605	1	56	2005	2005	NUM
bjp-81605	1	57	)	)	PUNCT
bjp-81605	1	58	.	.	PUNCT
bjp-81605	2	1	conventional	conventional	ADJ
bjp-81605	2	2	cancer	cancer	NOUN
bjp-81605	2	3	therapies	therapy	NOUN
bjp-81605	2	4	,	,	PUNCT
bjp-81605	2	5	such	such	ADJ
bjp-81605	2	6	as	as	ADP
bjp-81605	2	7	chemotherapy	chemotherapy	NOUN
bjp-81605	2	8	,	,	PUNCT
bjp-81605	2	9	often	often	ADV
bjp-81605	2	10	have	have	VERB
bjp-81605	2	11	significant	significant	ADJ
bjp-81605	2	12	adverse	adverse	ADJ
bjp-81605	2	13	effects	effect	NOUN
bjp-81605	2	14	.	.	PUNCT
bjp-81605	3	1	consequently	consequently	ADV
bjp-81605	3	2	,	,	PUNCT
bjp-81605	3	3	when	when	SCONJ
bjp-81605	3	4	these	these	DET
bjp-81605	3	5	drugs	drug	NOUN
bjp-81605	3	6	are	be	AUX
bjp-81605	3	7	administered	administer	VERB
bjp-81605	3	8	systemically	systemically	ADV
bjp-81605	3	9	,	,	PUNCT
bjp-81605	3	10	tumor	tumor	NOUN
bjp-81605	3	11	cells	cell	NOUN
bjp-81605	3	12	can	can	AUX
bjp-81605	3	13	develop	develop	VERB
bjp-81605	3	14	resistance	resistance	NOUN
bjp-81605	3	15	due	due	ADP
bjp-81605	3	16	to	to	ADP
bjp-81605	3	17	alterations	alteration	NOUN
bjp-81605	3	18	in	in	ADP
bjp-81605	3	19	metabolism	metabolism	NOUN
bjp-81605	3	20	,	,	PUNCT
bjp-81605	3	21	gene	gene	NOUN
bjp-81605	3	22	mutation	mutation	NOUN
bjp-81605	3	23	,	,	PUNCT
bjp-81605	3	24	and	and	CCONJ
bjp-81605	3	25	epigenetic	epigenetic	ADJ
bjp-81605	3	26	modifications	modification	NOUN
bjp-81605	3	27	.	.	PUNCT
bjp-81605	4	1	highly	highly	ADV
bjp-81605	4	2	metastatic	metastatic	ADJ
bjp-81605	4	3	cells	cell	NOUN
bjp-81605	4	4	are	be	AUX
bjp-81605	4	5	typically	typically	ADV
bjp-81605	4	6	mutant	mutant	ADJ
bjp-81605	4	7	cells	cell	NOUN
bjp-81605	4	8	.	.	PUNCT
bjp-81605	5	1	metastasis	metastasis	PRON
bjp-81605	5	2	results	result	VERB
bjp-81605	5	3	from	from	ADP
bjp-81605	5	4	the	the	DET
bjp-81605	5	5	balance	balance	NOUN
bjp-81605	5	6	between	between	ADP
bjp-81605	5	7	proand	proand	NOUN
bjp-81605	5	8	antiangiogenic	antiangiogenic	ADJ
bjp-81605	5	9	growth	growth	NOUN
bjp-81605	5	10	factors	factor	NOUN
bjp-81605	5	11	,	,	PUNCT
bjp-81605	5	12	which	which	PRON
bjp-81605	5	13	,	,	PUNCT
bjp-81605	5	14	when	when	SCONJ
bjp-81605	5	15	present	present	ADJ
bjp-81605	5	16	in	in	ADP
bjp-81605	5	17	high	high	ADJ
bjp-81605	5	18	concentrations	concentration	NOUN
bjp-81605	5	19	,	,	PUNCT
bjp-81605	5	20	can	can	AUX
bjp-81605	5	21	promote	promote	VERB
bjp-81605	5	22	the	the	DET
bjp-81605	5	23	growth	growth	NOUN
bjp-81605	5	24	of	of	ADP
bjp-81605	5	25	tumor	tumor	NOUN
bjp-81605	5	26	cells	cell	NOUN
bjp-81605	5	27	.	.	PUNCT
bjp-81605	6	1	vascular	vascular	ADJ
bjp-81605	6	2	endothelial	endothelial	ADJ
bjp-81605	6	3	growth	growth	NOUN
bjp-81605	6	4	factor	factor	NOUN
bjp-81605	6	5	(	(	PUNCT
bjp-81605	6	6	vegf	vegf	PROPN
bjp-81605	6	7	)	)	PUNCT
bjp-81605	6	8	provides	provide	VERB
bjp-81605	6	9	essential	essential	ADJ
bjp-81605	6	10	nutrients	nutrient	NOUN
bjp-81605	6	11	to	to	ADP
bjp-81605	6	12	tumor	tumor	NOUN
bjp-81605	6	13	cells	cell	NOUN
bjp-81605	6	14	.	.	PUNCT
bjp-81605	7	1	angiogenesis	angiogenesis	NOUN
bjp-81605	7	2	and	and	CCONJ
bjp-81605	7	3	tumor	tumor	NOUN
bjp-81605	7	4	metastasis	metastasis	NOUN
bjp-81605	7	5	are	be	AUX
bjp-81605	7	6	significantly	significantly	ADV
bjp-81605	7	7	influenced	influence	VERB
bjp-81605	7	8	by	by	ADP
bjp-81605	7	9	the	the	DET
bjp-81605	7	10	release	release	NOUN
bjp-81605	7	11	of	of	ADP
bjp-81605	7	12	pro	pro	ADJ
bjp-81605	7	13	-	-	ADJ
bjp-81605	7	14	angiogenic	angiogenic	ADJ
bjp-81605	7	15	factors	factor	NOUN
bjp-81605	7	16	from	from	ADP
bjp-81605	7	17	both	both	CCONJ
bjp-81605	7	18	endothelial	endothelial	ADJ
bjp-81605	7	19	and	and	CCONJ
bjp-81605	7	20	tumor	tumor	NOUN
bjp-81605	7	21	cells	cell	NOUN
bjp-81605	7	22	(	(	PUNCT
bjp-81605	7	23	mabeta	mabeta	NOUN
bjp-81605	7	24	et	et	PROPN
bjp-81605	7	25	al	al	PROPN
bjp-81605	7	26	.	.	PROPN
bjp-81605	7	27	,	,	PUNCT
bjp-81605	7	28	2022	2022	NUM
bjp-81605	7	29	)	)	PUNCT
bjp-81605	7	30	.	.	PUNCT
bjp-81605	8	1	the	the	DET
bjp-81605	8	2	vegf	vegf	PROPN
bjp-81605	8	3	family	family	PROPN
bjp-81605	8	4	exerts	exert	VERB
bjp-81605	8	5	its	its	PRON
bjp-81605	8	6	biological	biological	ADJ
bjp-81605	8	7	effects	effect	NOUN
bjp-81605	8	8	through	through	ADP
bjp-81605	8	9	interactions	interaction	NOUN
bjp-81605	8	10	with	with	ADP
bjp-81605	8	11	the	the	DET
bjp-81605	8	12	transmembrane	transmembrane	ADJ
bjp-81605	8	13	tyrosine	tyrosine	NOUN
bjp-81605	8	14	kinases	kinase	NOUN
bjp-81605	8	15	,	,	PUNCT
bjp-81605	8	16	including	include	VERB
bjp-81605	8	17	vascular	vascular	ADJ
bjp-81605	8	18	endothelial	endothelial	ADJ
bjp-81605	8	19	growth	growth	NOUN
bjp-81605	8	20	factor	factor	NOUN
bjp-81605	8	21	receptor	receptor	NOUN
bjp-81605	8	22	(	(	PUNCT
bjp-81605	8	23	vegfr1	vegfr1	NOUN
bjp-81605	8	24	or	or	CCONJ
bjp-81605	8	25	vegfr2	vegfr2	NOUN
bjp-81605	8	26	)	)	PUNCT
bjp-81605	8	27	.	.	PUNCT
bjp-81605	9	1	through	through	ADP
bjp-81605	9	2	signal	signal	ADJ
bjp-81605	9	3	transduction	transduction	NOUN
bjp-81605	9	4	molecules	molecule	NOUN
bjp-81605	9	5	pi3k	pi3k	PROPN
bjp-81605	9	6	and	and	CCONJ
bjp-81605	9	7	erk1/2	erk1/2	PROPN
bjp-81605	9	8	,	,	PUNCT
bjp-81605	9	9	the	the	DET
bjp-81605	9	10	high	high	ADJ
bjp-81605	9	11	-	-	PUNCT
bjp-81605	9	12	affinity	affinity	NOUN
bjp-81605	9	13	ligands	ligand	NOUN
bjp-81605	9	14	for	for	ADP
bjp-81605	9	15	vegfr1	vegfr1	NOUN
bjp-81605	9	16	,	,	PUNCT
bjp-81605	9	17	including	include	VERB
bjp-81605	9	18	vegf	vegf	PROPN
bjp-81605	9	19	-	-	PUNCT
bjp-81605	9	20	a	a	PROPN
bjp-81605	9	21	,	,	PUNCT
bjp-81605	9	22	vegf	vegf	PROPN
bjp-81605	9	23	-	-	PUNCT
bjp-81605	9	24	b	b	PROPN
bjp-81605	9	25	,	,	PUNCT
bjp-81605	9	26	pigf	pigf	NOUN
bjp-81605	9	27	,	,	PUNCT
bjp-81605	9	28	and	and	CCONJ
bjp-81605	9	29	vegf	vegf	PROPN
bjp-81605	9	30	-	-	PUNCT
bjp-81605	9	31	c	c	PROPN
bjp-81605	9	32	,	,	PUNCT
bjp-81605	9	33	bind	bind	VERB
bjp-81605	9	34	to	to	ADP
bjp-81605	9	35	vegf	vegf	PROPN
bjp-81605	9	36	-	-	PUNCT
bjp-81605	9	37	a	a	PROPN
bjp-81605	9	38	,	,	PUNCT
bjp-81605	9	39	vegf	vegf	PROPN
bjp-81605	9	40	-	-	PUNCT
bjp-81605	9	41	c	c	PROPN
bjp-81605	9	42	,	,	PUNCT
bjp-81605	9	43	and	and	CCONJ
bjp-81605	9	44	vegf	vegf	PROPN
bjp-81605	9	45	-	-	PUNCT
bjp-81605	9	46	e	e	PROPN
bjp-81605	9	47	,	,	PUNCT
bjp-81605	9	48	activating	activate	VERB
bjp-81605	9	49	the	the	DET
bjp-81605	9	50	downstream	downstream	ADJ
bjp-81605	9	51	signaling	signal	VERB
bjp-81605	9	52	pathways	pathway	NOUN
bjp-81605	9	53	involving	involve	VERB
bjp-81605	9	54	pi3k	pi3k	PROPN
bjp-81605	9	55	and	and	CCONJ
bjp-81605	9	56	erk1/2	erk1/2	PROPN
bjp-81605	9	57	.	.	PUNCT
bjp-81605	10	1	this	this	DET
bjp-81605	10	2	ligand	ligand	NOUN
bjp-81605	10	3	-	-	PUNCT
bjp-81605	10	4	receptor	receptor	NOUN
bjp-81605	10	5	interaction	interaction	NOUN
bjp-81605	10	6	triggers	trigger	NOUN
bjp-81605	10	7	signaling	signal	VERB
bjp-81605	10	8	pathways	pathway	NOUN
bjp-81605	10	9	that	that	PRON
bjp-81605	10	10	promote	promote	VERB
bjp-81605	10	11	cell	cell	NOUN
bjp-81605	10	12	invasion	invasion	NOUN
bjp-81605	10	13	,	,	PUNCT
bjp-81605	10	14	migration	migration	NOUN
bjp-81605	10	15	,	,	PUNCT
bjp-81605	10	16	proliferation	proliferation	NOUN
bjp-81605	10	17	,	,	PUNCT
bjp-81605	10	18	and	and	CCONJ
bjp-81605	10	19	enhanced	enhance	VERB
bjp-81605	10	20	vascular	vascular	ADJ
bjp-81605	10	21	permeability	permeability	NOUN
bjp-81605	10	22	(	(	PUNCT
bjp-81605	10	23	wang	wang	PROPN
bjp-81605	10	24	,	,	PUNCT
bjp-81605	10	25	2020	2020	NUM
bjp-81605	10	26	;	;	PUNCT
bjp-81605	10	27	zanjanchi	zanjanchi	PROPN
bjp-81605	10	28	et	et	PROPN
bjp-81605	10	29	al	al	PROPN
bjp-81605	10	30	.	.	PROPN
bjp-81605	10	31	,	,	PUNCT
bjp-81605	10	32	2022	2022	NUM
bjp-81605	10	33	)	)	PUNCT
bjp-81605	10	34	.	.	PUNCT
bjp-81605	11	1	most	most	ADJ
bjp-81605	11	2	studies	study	NOUN
bjp-81605	11	3	have	have	AUX
bjp-81605	11	4	focused	focus	VERB
bjp-81605	11	5	on	on	ADP
bjp-81605	11	6	the	the	DET
bjp-81605	11	7	vegf	vegf	PROPN
bjp-81605	11	8	/	/	SYM
bjp-81605	11	9	vegfr	vegfr	PROPN
bjp-81605	11	10	anti	anti	ADJ
bjp-81605	11	11	-	-	ADJ
bjp-81605	11	12	angiogenic	angiogenic	ADJ
bjp-81605	11	13	signaling	signal	VERB
bjp-81605	11	14	pathways	pathway	NOUN
bjp-81605	11	15	involved	involve	VERB
bjp-81605	11	16	in	in	ADP
bjp-81605	11	17	the	the	DET
bjp-81605	11	18	vegf	vegf	NOUN
bjp-81605	11	19	and	and	CCONJ
bjp-81605	11	20	vegfr	vegfr	NOUN
bjp-81605	11	21	.	.	PUNCT
bjp-81605	12	1	however	however	ADV
bjp-81605	12	2	,	,	PUNCT
bjp-81605	12	3	monoclonal	monoclonal	ADJ
bjp-81605	12	4	antibody	antibody	NOUN
bjp-81605	12	5	treatments	treatment	NOUN
bjp-81605	12	6	face	face	VERB
bjp-81605	12	7	several	several	ADJ
bjp-81605	12	8	therapeutic	therapeutic	ADJ
bjp-81605	12	9	challenges	challenge	NOUN
bjp-81605	12	10	,	,	PUNCT
bjp-81605	12	11	including	include	VERB
bjp-81605	12	12	suboptimal	suboptimal	ADJ
bjp-81605	12	13	pharmacokinetics	pharmacokinetic	NOUN
bjp-81605	12	14	,	,	PUNCT
bjp-81605	12	15	significant	significant	ADJ
bjp-81605	12	16	therapeutic	therapeutic	ADJ
bjp-81605	12	17	resistance	resistance	NOUN
bjp-81605	12	18	,	,	PUNCT
bjp-81605	12	19	and	and	CCONJ
bjp-81605	12	20	diminished	diminish	VERB
bjp-81605	12	21	sensiabstract	sensiabstract	NOUN
bjp-81605	12	22	this	this	DET
bjp-81605	12	23	study	study	NOUN
bjp-81605	12	24	aims	aim	VERB
bjp-81605	12	25	to	to	PART
bjp-81605	12	26	evaluate	evaluate	VERB
bjp-81605	12	27	the	the	DET
bjp-81605	12	28	efficacy	efficacy	NOUN
bjp-81605	12	29	of	of	ADP
bjp-81605	12	30	the	the	DET
bjp-81605	12	31	crt2	crt2	PROPN
bjp-81605	12	32	peptide	peptide	NOUN
bjp-81605	12	33	in	in	ADP
bjp-81605	12	34	inhibiting	inhibit	VERB
bjp-81605	12	35	vegfr1	vegfr1	NOUN
bjp-81605	12	36	tyrosine	tyrosine	PROPN
bjp-81605	12	37	kinase	kinase	PROPN
bjp-81605	12	38	activity	activity	NOUN
bjp-81605	12	39	against	against	ADP
bjp-81605	12	40	solid	solid	ADJ
bjp-81605	12	41	tumors	tumor	NOUN
bjp-81605	12	42	.	.	PUNCT
bjp-81605	13	1	molecular	molecular	ADJ
bjp-81605	13	2	docking	docking	NOUN
bjp-81605	13	3	was	be	AUX
bjp-81605	13	4	performed	perform	VERB
bjp-81605	13	5	using	use	VERB
bjp-81605	13	6	cluspro	cluspro	ADJ
bjp-81605	13	7	2.0	2.0	NUM
bjp-81605	13	8	against	against	ADP
bjp-81605	13	9	the	the	DET
bjp-81605	13	10	vascular	vascular	ADJ
bjp-81605	13	11	endothelial	endothelial	ADJ
bjp-81605	13	12	growth	growth	NOUN
bjp-81605	13	13	factor	factor	NOUN
bjp-81605	13	14	receptor-1	receptor-1	NUM
bjp-81605	13	15	(	(	PUNCT
bjp-81605	13	16	vegfr1	vegfr1	NOUN
bjp-81605	13	17	)	)	PUNCT
bjp-81605	13	18	with	with	ADP
bjp-81605	13	19	crt2	crt2	PROPN
bjp-81605	13	20	.	.	PUNCT
bjp-81605	14	1	moreover	moreover	ADV
bjp-81605	14	2	,	,	PUNCT
bjp-81605	14	3	in	in	ADP
bjp-81605	14	4	vitro	vitro	X
bjp-81605	14	5	studies	study	NOUN
bjp-81605	14	6	were	be	AUX
bjp-81605	14	7	conducted	conduct	VERB
bjp-81605	14	8	using	use	VERB
bjp-81605	14	9	colorectal	colorectal	ADJ
bjp-81605	14	10	cancer	cancer	NOUN
bjp-81605	14	11	ht-116	ht-116	NOUN
bjp-81605	14	12	cell	cell	NOUN
bjp-81605	14	13	lines	line	NOUN
bjp-81605	14	14	to	to	PART
bjp-81605	14	15	investigate	investigate	VERB
bjp-81605	14	16	apoptosis	apoptosis	NOUN
bjp-81605	14	17	,	,	PUNCT
bjp-81605	14	18	cell	cell	NOUN
bjp-81605	14	19	cycle	cycle	NOUN
bjp-81605	14	20	analysis	analysis	NOUN
bjp-81605	14	21	,	,	PUNCT
bjp-81605	14	22	and	and	CCONJ
bjp-81605	14	23	peptide	peptide	ADJ
bjp-81605	14	24	binding	bind	VERB
bjp-81605	14	25	assays	assay	NOUN
bjp-81605	14	26	.	.	PUNCT
bjp-81605	15	1	the	the	DET
bjp-81605	15	2	mtt	mtt	NOUN
bjp-81605	15	3	assay	assay	VERB
bjp-81605	15	4	revealed	reveal	VERB
bjp-81605	15	5	a	a	DET
bjp-81605	15	6	significant	significant	ADJ
bjp-81605	15	7	variation	variation	NOUN
bjp-81605	15	8	in	in	ADP
bjp-81605	15	9	the	the	DET
bjp-81605	15	10	ic50	ic50	PROPN
bjp-81605	15	11	value	value	NOUN
bjp-81605	15	12	,	,	PUNCT
bjp-81605	15	13	with	with	ADP
bjp-81605	15	14	a	a	DET
bjp-81605	15	15	result	result	NOUN
bjp-81605	15	16	of	of	ADP
bjp-81605	15	17	16.0	16.0	NUM
bjp-81605	15	18	μg	μg	NOUN
bjp-81605	15	19	/	/	SYM
bjp-81605	15	20	ml	ml	PROPN
bjp-81605	15	21	.	.	PUNCT
bjp-81605	16	1	the	the	DET
bjp-81605	16	2	anti	anti	ADJ
bjp-81605	16	3	-	-	ADJ
bjp-81605	16	4	cancer	cancer	ADJ
bjp-81605	16	5	activity	activity	NOUN
bjp-81605	16	6	of	of	ADP
bjp-81605	16	7	crt2	crt2	PROPN
bjp-81605	16	8	was	be	AUX
bjp-81605	16	9	by	by	ADP
bjp-81605	16	10	apoptosis	apoptosis	NOUN
bjp-81605	16	11	(	(	PUNCT
bjp-81605	16	12	45.7	45.7	NUM
bjp-81605	16	13	%	%	NOUN
bjp-81605	16	14	)	)	PUNCT
bjp-81605	16	15	and	and	CCONJ
bjp-81605	16	16	dose	dose	NOUN
bjp-81605	16	17	-	-	PUNCT
bjp-81605	16	18	dependent	dependent	ADJ
bjp-81605	16	19	cell	cell	NOUN
bjp-81605	16	20	cycle	cycle	NOUN
bjp-81605	16	21	g1/	g1/	VERB
bjp-81605	16	22	s	s	NOUN
bjp-81605	16	23	phase	phase	NOUN
bjp-81605	16	24	arrest	arrest	NOUN
bjp-81605	16	25	in	in	ADP
bjp-81605	16	26	colorectal	colorectal	ADJ
bjp-81605	16	27	cancer	cancer	NOUN
bjp-81605	16	28	cell	cell	NOUN
bjp-81605	16	29	lines	line	NOUN
bjp-81605	16	30	.	.	PUNCT
bjp-81605	17	1	furthermore	furthermore	ADV
bjp-81605	17	2	,	,	PUNCT
bjp-81605	17	3	the	the	DET
bjp-81605	17	4	consequences	consequence	NOUN
bjp-81605	17	5	showed	show	VERB
bjp-81605	17	6	that	that	SCONJ
bjp-81605	17	7	crt2	crt2	PROPN
bjp-81605	17	8	deterred	deter	VERB
bjp-81605	17	9	the	the	DET
bjp-81605	17	10	pi3k	pi3k	PROPN
bjp-81605	17	11	/	/	SYM
bjp-81605	17	12	akt	akt	PROPN
bjp-81605	17	13	signaling	signal	VERB
bjp-81605	17	14	pathway	pathway	NOUN
bjp-81605	17	15	in	in	ADP
bjp-81605	17	16	a	a	DET
bjp-81605	17	17	dosedependent	dosedependent	NOUN
bjp-81605	17	18	manner	manner	NOUN
bjp-81605	17	19	.	.	PUNCT
bjp-81605	18	1	the	the	DET
bjp-81605	18	2	outcomes	outcome	NOUN
bjp-81605	18	3	of	of	ADP
bjp-81605	18	4	the	the	DET
bjp-81605	18	5	present	present	ADJ
bjp-81605	18	6	study	study	NOUN
bjp-81605	18	7	indicate	indicate	VERB
bjp-81605	18	8	that	that	SCONJ
bjp-81605	18	9	crt2	crt2	PROPN
bjp-81605	18	10	employed	employ	VERB
bjp-81605	18	11	selective	selective	ADJ
bjp-81605	18	12	anti	anti	ADJ
bjp-81605	18	13	-	-	ADJ
bjp-81605	18	14	cancer	cancer	ADJ
bjp-81605	18	15	effects	effect	NOUN
bjp-81605	18	16	on	on	ADP
bjp-81605	18	17	ht-116	ht-116	PROPN
bjp-81605	18	18	cell	cell	NOUN
bjp-81605	18	19	lines	line	NOUN
bjp-81605	18	20	through	through	ADP
bjp-81605	18	21	cell	cell	NOUN
bjp-81605	18	22	cycle	cycle	NOUN
bjp-81605	18	23	arrest	arrest	NOUN
bjp-81605	18	24	,	,	PUNCT
bjp-81605	18	25	apoptosis	apoptosis	NOUN
bjp-81605	18	26	,	,	PUNCT
bjp-81605	18	27	and	and	CCONJ
bjp-81605	18	28	inhibition	inhibition	NOUN
bjp-81605	18	29	of	of	ADP
bjp-81605	18	30	the	the	DET
bjp-81605	18	31	pi3k	pi3k	PROPN
bjp-81605	18	32	/	/	SYM
bjp-81605	18	33	akt	akt	PROPN
bjp-81605	18	34	signaling	signal	VERB
bjp-81605	18	35	pathways	pathway	NOUN
bjp-81605	18	36	.	.	PUNCT
bjp-81605	19	1	article	article	NOUN
bjp-81605	19	2	info	info	NOUN
bjp-81605	19	3	received	receive	VERB
bjp-81605	19	4	:	:	PUNCT
bjp-81605	19	5	10	10	NUM
bjp-81605	19	6	may	may	AUX
bjp-81605	19	7	2025	2025	NUM
bjp-81605	19	8	accepted	accept	VERB
bjp-81605	19	9	:	:	PUNCT
bjp-81605	19	10	11	11	NUM
bjp-81605	19	11	july	july	PROPN
bjp-81605	19	12	2025	2025	NUM
bjp-81605	19	13	available	available	ADJ
bjp-81605	19	14	online	online	ADV
bjp-81605	19	15	:	:	PUNCT
bjp-81605	19	16	31	31	NUM
bjp-81605	19	17	august	august	PROPN
bjp-81605	19	18	2025	2025	NUM
bjp-81605	19	19	doi	doi	NOUN
bjp-81605	19	20	:	:	PUNCT
bjp-81605	19	21	10.3329	10.3329	NUM
bjp-81605	19	22	/	/	SYM
bjp-81605	19	23	bjp.v20i3.81605	bjp.v20i3.81605	PROPN
bjp-81605	19	24	cite	cite	VERB
bjp-81605	19	25	this	this	DET
bjp-81605	19	26	article	article	NOUN
bjp-81605	19	27	:	:	PUNCT
bjp-81605	19	28	yogananthan	yogananthan	PROPN
bjp-81605	19	29	d	d	PROPN
bjp-81605	19	30	,	,	PUNCT
bjp-81605	19	31	venkatachalam	venkatachalam	PROPN
bjp-81605	19	32	ark	ark	PROPN
bjp-81605	19	33	,	,	PUNCT
bjp-81605	19	34	muthiah	muthiah	PROPN
bjp-81605	19	35	r.	r.	PROPN
bjp-81605	19	36	novel	novel	PROPN
bjp-81605	19	37	crt2	crt2	PROPN
bjp-81605	19	38	peptide	peptide	NOUN
bjp-81605	19	39	inhibits	inhibit	VERB
bjp-81605	19	40	tumor	tumor	NOUN
bjp-81605	19	41	growth	growth	NOUN
bjp-81605	19	42	and	and	CCONJ
bjp-81605	19	43	angiogenesis	angiogenesis	NOUN
bjp-81605	19	44	in	in	ADP
bjp-81605	19	45	colorectal	colorectal	ADJ
bjp-81605	19	46	cancer	cancer	NOUN
bjp-81605	19	47	ht-116	ht-116	NOUN
bjp-81605	19	48	cell	cell	NOUN
bjp-81605	19	49	lines	line	NOUN
bjp-81605	19	50	via	via	ADP
bjp-81605	19	51	pi3k	pi3k	PROPN
bjp-81605	19	52	/	/	SYM
bjp-81605	19	53	erk	erk	NOUN
bjp-81605	19	54	signaling	signal	VERB
bjp-81605	19	55	pathway	pathway	NOUN
bjp-81605	19	56	.	.	PUNCT
bjp-81605	20	1	bangladesh	bangladesh	PROPN
bjp-81605	20	2	j	j	PROPN
bjp-81605	20	3	pharmacol	pharmacol	PROPN
bjp-81605	20	4	.	.	PUNCT
bjp-81605	21	1	2025	2025	NUM
bjp-81605	21	2	;	;	PUNCT
bjp-81605	21	3	20	20	NUM
bjp-81605	21	4	:	:	SYM
bjp-81605	21	5	89100	89100	NUM
bjp-81605	21	6	.	.	PUNCT
bjp-81605	22	1	novel	novel	ADJ
bjp-81605	22	2	crt2	crt2	PROPN
bjp-81605	22	3	peptide	peptide	NOUN
bjp-81605	22	4	inhibits	inhibit	VERB
bjp-81605	22	5	tumor	tumor	NOUN
bjp-81605	22	6	growth	growth	NOUN
bjp-81605	22	7	and	and	CCONJ
bjp-81605	22	8	angiogenesis	angiogenesis	NOUN
bjp-81605	22	9	in	in	ADP
bjp-81605	22	10	colorectal	colorectal	ADJ
bjp-81605	22	11	cancer	cancer	NOUN
bjp-81605	22	12	ht-116	ht-116	NOUN
bjp-81605	22	13	cell	cell	NOUN
bjp-81605	22	14	lines	line	NOUN
bjp-81605	22	15	via	via	ADP
bjp-81605	22	16	pi3k	pi3k	PROPN
bjp-81605	22	17	/	/	SYM
bjp-81605	22	18	erk	erk	NOUN
bjp-81605	22	19	signaling	signal	VERB
bjp-81605	22	20	pathway	pathway	NOUN
bjp-81605	22	21	dhanapal	dhanapal	ADJ
bjp-81605	22	22	yogananthan1	yogananthan1	NOUN
bjp-81605	22	23	,	,	PUNCT
bjp-81605	22	24	ashok	ashok	PROPN
bjp-81605	22	25	raj	raj	PROPN
bjp-81605	22	26	kattur	kattur	PROPN
bjp-81605	22	27	venkatachalam2	venkatachalam2	PROPN
bjp-81605	22	28	,	,	PUNCT
bjp-81605	22	29	and	and	CCONJ
bjp-81605	22	30	ramanathan	ramanathan	PROPN
bjp-81605	22	31	muthiah1	muthiah1	PROPN
bjp-81605	22	32	1department	1department	NUM
bjp-81605	22	33	of	of	ADP
bjp-81605	22	34	pharmacology	pharmacology	NOUN
bjp-81605	22	35	,	,	PUNCT
bjp-81605	22	36	psg	psg	PROPN
bjp-81605	22	37	college	college	PROPN
bjp-81605	22	38	of	of	ADP
bjp-81605	22	39	pharmacy	pharmacy	NOUN
bjp-81605	22	40	,	,	PUNCT
bjp-81605	22	41	coimbatore	coimbatore	PROPN
bjp-81605	22	42	,	,	PUNCT
bjp-81605	22	43	tamil	tamil	NOUN
bjp-81605	22	44	nadu-641004	nadu-641004	PROPN
bjp-81605	22	45	,	,	PUNCT
bjp-81605	22	46	india	india	PROPN
bjp-81605	22	47	;	;	PUNCT
bjp-81605	22	48	2department	2department	NUM
bjp-81605	22	49	of	of	ADP
bjp-81605	22	50	microbiology	microbiology	NOUN
bjp-81605	22	51	,	,	PUNCT
bjp-81605	22	52	psg	psg	PROPN
bjp-81605	22	53	college	college	PROPN
bjp-81605	22	54	of	of	ADP
bjp-81605	22	55	arts	art	NOUN
bjp-81605	22	56	and	and	CCONJ
bjp-81605	22	57	science	science	NOUN
bjp-81605	22	58	,	,	PUNCT
bjp-81605	22	59	coimbatore	coimbatore	PROPN
bjp-81605	22	60	,	,	PUNCT
bjp-81605	22	61	tamil	tamil	PROPN
bjp-81605	22	62	nadu-641014	nadu-641014	PROPN
bjp-81605	22	63	,	,	PUNCT
bjp-81605	22	64	india	india	PROPN
bjp-81605	22	65	.	.	PUNCT
bjp-81605	23	1	this	this	DET
bjp-81605	23	2	work	work	NOUN
bjp-81605	23	3	is	be	AUX
bjp-81605	23	4	licensed	license	VERB
bjp-81605	23	5	under	under	ADP
bjp-81605	23	6	a	a	DET
bjp-81605	23	7	creative	creative	ADJ
bjp-81605	23	8	commons	common	NOUN
bjp-81605	23	9	attribution	attribution	NOUN
bjp-81605	23	10	4.0	4.0	NUM
bjp-81605	23	11	license	license	NOUN
bjp-81605	23	12	.	.	PUNCT
bjp-81605	24	1	you	you	PRON
bjp-81605	24	2	are	be	AUX
bjp-81605	24	3	free	free	ADJ
bjp-81605	24	4	to	to	PART
bjp-81605	24	5	copy	copy	VERB
bjp-81605	24	6	,	,	PUNCT
bjp-81605	24	7	distribute	distribute	VERB
bjp-81605	24	8	and	and	CCONJ
bjp-81605	24	9	perform	perform	VERB
bjp-81605	24	10	the	the	DET
bjp-81605	24	11	work	work	NOUN
bjp-81605	24	12	.	.	PUNCT
bjp-81605	25	1	you	you	PRON
bjp-81605	25	2	must	must	AUX
bjp-81605	25	3	attribute	attribute	VERB
bjp-81605	25	4	the	the	DET
bjp-81605	25	5	work	work	NOUN
bjp-81605	25	6	in	in	ADP
bjp-81605	25	7	the	the	DET
bjp-81605	25	8	manner	manner	NOUN
bjp-81605	25	9	specified	specify	VERB
bjp-81605	25	10	by	by	ADP
bjp-81605	25	11	the	the	DET
bjp-81605	25	12	author	author	NOUN
bjp-81605	25	13	or	or	CCONJ
bjp-81605	25	14	licensor	licensor	NOUN
bjp-81605	25	15	.	.	PUNCT
bjp-81605	26	1	a	a	DET
bjp-81605	26	2	journal	journal	NOUN
bjp-81605	26	3	of	of	ADP
bjp-81605	26	4	the	the	DET
bjp-81605	26	5	bangladesh	bangladesh	NOUN
bjp-81605	26	6	pharmacological	pharmacological	ADJ
bjp-81605	26	7	society	society	NOUN
bjp-81605	26	8	(	(	PUNCT
bjp-81605	26	9	bdps	bdps	NOUN
bjp-81605	26	10	)	)	PUNCT
bjp-81605	26	11	bangladesh	bangladesh	PROPN
bjp-81605	26	12	j	j	PROPN
bjp-81605	26	13	pharmacol	pharmacol	PROPN
bjp-81605	26	14	2025	2025	NUM
bjp-81605	26	15	;	;	PUNCT
bjp-81605	26	16	20	20	NUM
bjp-81605	26	17	:	:	SYM
bjp-81605	26	18	89	89	NUM
bjp-81605	26	19	-	-	SYM
bjp-81605	26	20	100	100	NUM
bjp-81605	26	21	journal	journal	NOUN
bjp-81605	26	22	homepage	homepage	NOUN
bjp-81605	26	23	:	:	PUNCT
bjp-81605	26	24	www.bdpsjournal.org	www.bdpsjournal.org	NUM
bjp-81605	26	25	;	;	PUNCT
bjp-81605	26	26	www.banglajol.info	www.banglajol.info	PROPN
bjp-81605	26	27	abstracted	abstract	VERB
bjp-81605	26	28	/	/	SYM
bjp-81605	26	29	indexed	index	VERB
bjp-81605	26	30	in	in	ADP
bjp-81605	26	31	academic	academic	ADJ
bjp-81605	26	32	search	search	NOUN
bjp-81605	26	33	complete	complete	ADJ
bjp-81605	26	34	,	,	PUNCT
bjp-81605	26	35	agroforestry	agroforestry	NOUN
bjp-81605	26	36	abstracts	abstract	NOUN
bjp-81605	26	37	,	,	PUNCT
bjp-81605	26	38	asia	asia	PROPN
bjp-81605	26	39	journals	journal	NOUN
bjp-81605	26	40	online	online	ADV
bjp-81605	26	41	,	,	PUNCT
bjp-81605	26	42	bangladesh	bangladesh	NOUN
bjp-81605	26	43	journals	journal	NOUN
bjp-81605	26	44	online	online	ADV
bjp-81605	26	45	,	,	PUNCT
bjp-81605	26	46	biological	biological	ADJ
bjp-81605	26	47	abstracts	abstract	NOUN
bjp-81605	26	48	,	,	PUNCT
bjp-81605	26	49	biosis	biosis	NOUN
bjp-81605	26	50	previews	preview	NOUN
bjp-81605	26	51	,	,	PUNCT
bjp-81605	26	52	cab	cab	NOUN
bjp-81605	26	53	abstracts	abstract	NOUN
bjp-81605	26	54	,	,	PUNCT
bjp-81605	26	55	current	current	ADJ
bjp-81605	26	56	abstracts	abstract	NOUN
bjp-81605	26	57	,	,	PUNCT
bjp-81605	26	58	directory	directory	NOUN
bjp-81605	26	59	of	of	ADP
bjp-81605	26	60	open	open	ADJ
bjp-81605	26	61	access	access	NOUN
bjp-81605	26	62	journals	journal	NOUN
bjp-81605	26	63	,	,	PUNCT
bjp-81605	26	64	embase	embase	NOUN
bjp-81605	26	65	/	/	SYM
bjp-81605	26	66	excerpta	excerpta	NOUN
bjp-81605	26	67	medica	medica	NOUN
bjp-81605	26	68	,	,	PUNCT
bjp-81605	26	69	global	global	ADJ
bjp-81605	26	70	health	health	NOUN
bjp-81605	26	71	,	,	PUNCT
bjp-81605	26	72	google	google	PROPN
bjp-81605	26	73	scholar	scholar	NOUN
bjp-81605	26	74	,	,	PUNCT
bjp-81605	26	75	hinari	hinari	X
bjp-81605	26	76	(	(	PUNCT
bjp-81605	26	77	who	who	PRON
bjp-81605	26	78	)	)	PUNCT
bjp-81605	26	79	,	,	PUNCT
bjp-81605	26	80	international	international	ADJ
bjp-81605	26	81	pharmaceutical	pharmaceutical	ADJ
bjp-81605	26	82	abstracts	abstract	NOUN
bjp-81605	26	83	,	,	PUNCT
bjp-81605	26	84	open	open	ADJ
bjp-81605	26	85	j	j	PROPN
bjp-81605	26	86	-	-	PUNCT
bjp-81605	26	87	gate	gate	NOUN
bjp-81605	26	88	,	,	PUNCT
bjp-81605	26	89	science	science	NOUN
bjp-81605	26	90	citation	citation	NOUN
bjp-81605	26	91	index	index	NOUN
bjp-81605	26	92	expanded	expand	VERB
bjp-81605	26	93	,	,	PUNCT
bjp-81605	26	94	scopus	scopus	NOUN
bjp-81605	26	95	and	and	CCONJ
bjp-81605	26	96	social	social	ADJ
bjp-81605	26	97	sciences	sciences	PROPN
bjp-81605	26	98	citation	citation	NOUN
bjp-81605	26	99	index	index	NOUN
bjp-81605	26	100	issn	issn	PROPN
bjp-81605	26	101	:	:	PUNCT
bjp-81605	26	102	1991	1991	NUM
bjp-81605	26	103	-	-	PUNCT
bjp-81605	26	104	0088	0088	NUM
bjp-81605	26	105	tivity	tivity	NOUN
bjp-81605	26	106	in	in	ADP
bjp-81605	26	107	clinical	clinical	ADJ
bjp-81605	26	108	outcomes	outcome	NOUN
bjp-81605	26	109	.	.	PUNCT
bjp-81605	27	1	these	these	DET
bjp-81605	27	2	therapies	therapy	NOUN
bjp-81605	27	3	target	target	VERB
bjp-81605	27	4	antivegf	antivegf	ADJ
bjp-81605	27	5	and	and	CCONJ
bjp-81605	27	6	small	small	ADJ
bjp-81605	27	7	-	-	PUNCT
bjp-81605	27	8	molecule	molecule	NOUN
bjp-81605	27	9	inhibitors	inhibitor	NOUN
bjp-81605	27	10	of	of	ADP
bjp-81605	27	11	tyrosine	tyrosine	NOUN
bjp-81605	27	12	kinases	kinase	NOUN
bjp-81605	27	13	.	.	PUNCT
bjp-81605	28	1	additionally	additionally	ADV
bjp-81605	28	2	,	,	PUNCT
bjp-81605	28	3	peptides	peptide	NOUN
bjp-81605	28	4	have	have	AUX
bjp-81605	28	5	emerged	emerge	VERB
bjp-81605	28	6	as	as	ADP
bjp-81605	28	7	a	a	DET
bjp-81605	28	8	promising	promising	ADJ
bjp-81605	28	9	new	new	ADJ
bjp-81605	28	10	class	class	NOUN
bjp-81605	28	11	of	of	ADP
bjp-81605	28	12	therapeutics	therapeutic	NOUN
bjp-81605	28	13	.	.	PUNCT
bjp-81605	29	1	numerous	numerous	ADJ
bjp-81605	29	2	bioactive	bioactive	ADJ
bjp-81605	29	3	peptide	peptide	NOUN
bjp-81605	29	4	compounds	compound	NOUN
bjp-81605	29	5	consisting	consist	VERB
bjp-81605	29	6	of	of	ADP
bjp-81605	29	7	modest	modest	ADJ
bjp-81605	29	8	molecular	molecular	ADJ
bjp-81605	29	9	weight	weight	NOUN
bjp-81605	29	10	fragments	fragment	NOUN
bjp-81605	29	11	,	,	PUNCT
bjp-81605	29	12	typically	typically	ADV
bjp-81605	29	13	ranging	range	VERB
bjp-81605	29	14	from	from	ADP
bjp-81605	29	15	10	10	NUM
bjp-81605	29	16	to	to	PART
bjp-81605	29	17	20	20	NUM
bjp-81605	29	18	amino	amino	NOUN
bjp-81605	29	19	acid	acid	NOUN
bjp-81605	29	20	residues	residue	NOUN
bjp-81605	29	21	,	,	PUNCT
bjp-81605	29	22	have	have	AUX
bjp-81605	29	23	recently	recently	ADV
bjp-81605	29	24	been	be	AUX
bjp-81605	29	25	the	the	DET
bjp-81605	29	26	focus	focus	NOUN
bjp-81605	29	27	of	of	ADP
bjp-81605	29	28	research	research	NOUN
bjp-81605	29	29	as	as	ADP
bjp-81605	29	30	potentially	potentially	ADV
bjp-81605	29	31	active	active	ADJ
bjp-81605	29	32	pharmacological	pharmacological	ADJ
bjp-81605	29	33	agents	agent	NOUN
bjp-81605	29	34	to	to	PART
bjp-81605	29	35	enhance	enhance	VERB
bjp-81605	29	36	health	health	NOUN
bjp-81605	29	37	(	(	PUNCT
bjp-81605	29	38	dia	dia	PROPN
bjp-81605	29	39	et	et	PROPN
bjp-81605	29	40	al	al	PROPN
bjp-81605	29	41	.	.	PROPN
bjp-81605	29	42	,	,	PUNCT
bjp-81605	29	43	2016	2016	NUM
bjp-81605	29	44	)	)	PUNCT
bjp-81605	29	45	.	.	PUNCT
bjp-81605	30	1	in	in	ADP
bjp-81605	30	2	contrast	contrast	NOUN
bjp-81605	30	3	,	,	PUNCT
bjp-81605	30	4	bg-4	bg-4	X
bjp-81605	30	5	,	,	PUNCT
bjp-81605	30	6	a	a	DET
bjp-81605	30	7	newly	newly	ADV
bjp-81605	30	8	discovered	discover	VERB
bjp-81605	30	9	peptide	peptide	NOUN
bjp-81605	30	10	derived	derive	VERB
bjp-81605	30	11	from	from	ADP
bjp-81605	30	12	bitter	bitter	ADJ
bjp-81605	30	13	groundnuts	groundnut	NOUN
bjp-81605	30	14	,	,	PUNCT
bjp-81605	30	15	demonstrates	demonstrate	VERB
bjp-81605	30	16	anti	anti	ADJ
bjp-81605	30	17	-	-	ADJ
bjp-81605	30	18	cancer	cancer	ADJ
bjp-81605	30	19	activity	activity	NOUN
bjp-81605	30	20	against	against	ADP
bjp-81605	30	21	ht-29	ht-29	PRON
bjp-81605	30	22	,	,	PUNCT
bjp-81605	30	23	ht-116	ht-116	PROPN
bjp-81605	30	24	,	,	PUNCT
bjp-81605	30	25	and	and	CCONJ
bjp-81605	30	26	sw420	sw420	PROPN
bjp-81605	30	27	cancer	cancer	NOUN
bjp-81605	30	28	cell	cell	NOUN
bjp-81605	30	29	lines	line	NOUN
bjp-81605	30	30	(	(	PUNCT
bjp-81605	30	31	shanthosa	shanthosa	PROPN
bjp-81605	30	32	et	et	PROPN
bjp-81605	30	33	al	al	PROPN
bjp-81605	30	34	.	.	PROPN
bjp-81605	30	35	,	,	PUNCT
bjp-81605	30	36	2013	2013	NUM
bjp-81605	30	37	)	)	PUNCT
bjp-81605	30	38	.	.	PUNCT
bjp-81605	31	1	garlic	garlic	NOUN
bjp-81605	31	2	(	(	PUNCT
bjp-81605	31	3	allium	allium	NOUN
bjp-81605	31	4	sativum	sativum	NOUN
bjp-81605	31	5	)	)	PUNCT
bjp-81605	31	6	is	be	AUX
bjp-81605	31	7	a	a	DET
bjp-81605	31	8	well	well	ADV
bjp-81605	31	9	-	-	PUNCT
bjp-81605	31	10	known	know	VERB
bjp-81605	31	11	plant	plant	NOUN
bjp-81605	31	12	recognized	recognize	VERB
bjp-81605	31	13	for	for	ADP
bjp-81605	31	14	its	its	PRON
bjp-81605	31	15	nutriational	nutriational	ADJ
bjp-81605	31	16	and	and	CCONJ
bjp-81605	31	17	preventive	preventive	ADJ
bjp-81605	31	18	health	health	NOUN
bjp-81605	31	19	benefits	benefit	NOUN
bjp-81605	31	20	.	.	PUNCT
bjp-81605	32	1	garlic	garlic	NOUN
bjp-81605	32	2	contains	contain	VERB
bjp-81605	32	3	organosulfur	organosulfur	NOUN
bjp-81605	32	4	compounds	compound	NOUN
bjp-81605	32	5	,	,	PUNCT
bjp-81605	32	6	such	such	ADJ
bjp-81605	32	7	as	as	ADP
bjp-81605	32	8	diallyl	diallyl	NOUN
bjp-81605	32	9	derivatives	derivative	NOUN
bjp-81605	32	10	,	,	PUNCT
bjp-81605	32	11	which	which	PRON
bjp-81605	32	12	have	have	AUX
bjp-81605	32	13	demonstrated	demonstrate	VERB
bjp-81605	32	14	anticancer	anticancer	NOUN
bjp-81605	32	15	effects	effect	NOUN
bjp-81605	32	16	across	across	ADP
bjp-81605	32	17	various	various	ADJ
bjp-81605	32	18	tumor	tumor	NOUN
bjp-81605	32	19	models	model	NOUN
bjp-81605	32	20	in	in	ADP
bjp-81605	32	21	both	both	CCONJ
bjp-81605	32	22	in	in	ADP
bjp-81605	32	23	vitro	vitro	X
bjp-81605	32	24	and	and	CCONJ
bjp-81605	32	25	in	in	ADP
bjp-81605	32	26	vivo	vivo	ADJ
bjp-81605	32	27	systems	system	NOUN
bjp-81605	32	28	(	(	PUNCT
bjp-81605	32	29	he	he	PRON
bjp-81605	32	30	et	et	PROPN
bjp-81605	32	31	al	al	PROPN
bjp-81605	32	32	.	.	PROPN
bjp-81605	32	33	,	,	PUNCT
bjp-81605	32	34	2013	2013	NUM
bjp-81605	32	35	)	)	PUNCT
bjp-81605	32	36	.	.	PUNCT
bjp-81605	33	1	among	among	ADP
bjp-81605	33	2	these	these	PRON
bjp-81605	33	3	,	,	PUNCT
bjp-81605	33	4	the	the	DET
bjp-81605	33	5	garlic	garlic	NOUN
bjp-81605	33	6	-	-	PUNCT
bjp-81605	33	7	derived	derive	VERB
bjp-81605	33	8	peptide	peptide	NOUN
bjp-81605	33	9	vs-9	vs-9	PUNCT
bjp-81605	33	10	has	have	VERB
bjp-81605	33	11	significant	significant	ADJ
bjp-81605	33	12	antileukemic	antileukemic	ADJ
bjp-81605	33	13	activity	activity	NOUN
bjp-81605	33	14	against	against	ADP
bjp-81605	33	15	k562	k562	PROPN
bjp-81605	33	16	and	and	CCONJ
bjp-81605	33	17	molt-4	molt-4	NUM
bjp-81605	33	18	cell	cell	NOUN
bjp-81605	33	19	lines	line	NOUN
bjp-81605	33	20	through	through	ADP
bjp-81605	33	21	its	its	PRON
bjp-81605	33	22	interaction	interaction	NOUN
bjp-81605	33	23	with	with	ADP
bjp-81605	33	24	the	the	DET
bjp-81605	33	25	bid	bid	NOUN
bjp-81605	33	26	-	-	PUNCT
bjp-81605	33	27	bh3	bh3	NOUN
bjp-81605	33	28	complex	complex	ADJ
bjp-81605	33	29	proteins	protein	NOUN
bjp-81605	33	30	,	,	PUNCT
bjp-81605	33	31	which	which	PRON
bjp-81605	33	32	are	be	AUX
bjp-81605	33	33	key	key	ADJ
bjp-81605	33	34	regulators	regulator	NOUN
bjp-81605	33	35	in	in	ADP
bjp-81605	33	36	apoptotic	apoptotic	ADJ
bjp-81605	33	37	pathways	pathway	NOUN
bjp-81605	33	38	.	.	PUNCT
bjp-81605	34	1	programmed	program	VERB
bjp-81605	34	2	cell	cell	NOUN
bjp-81605	34	3	death	death	NOUN
bjp-81605	34	4	(	(	PUNCT
bjp-81605	34	5	apoptosis	apoptosis	NOUN
bjp-81605	34	6	)	)	PUNCT
bjp-81605	34	7	is	be	AUX
bjp-81605	34	8	a	a	DET
bjp-81605	34	9	cellcontrolled	cellcontrolle	VERB
bjp-81605	34	10	biological	biological	ADJ
bjp-81605	34	11	process	process	NOUN
bjp-81605	34	12	that	that	PRON
bjp-81605	34	13	can	can	AUX
bjp-81605	34	14	be	be	AUX
bjp-81605	34	15	triggered	trigger	VERB
bjp-81605	34	16	via	via	ADP
bjp-81605	34	17	extrinsic	extrinsic	ADJ
bjp-81605	34	18	or	or	CCONJ
bjp-81605	34	19	intrinsic	intrinsic	ADJ
bjp-81605	34	20	stimuli	stimulus	NOUN
bjp-81605	34	21	(	(	PUNCT
bjp-81605	34	22	dey	dey	NOUN
bjp-81605	34	23	,	,	PUNCT
bjp-81605	34	24	2021	2021	NUM
bjp-81605	34	25	;	;	PUNCT
bjp-81605	34	26	zhang	zhang	PROPN
bjp-81605	34	27	et	et	PROPN
bjp-81605	34	28	al	al	PROPN
bjp-81605	34	29	.	.	PROPN
bjp-81605	34	30	,	,	PUNCT
bjp-81605	34	31	2021	2021	NUM
bjp-81605	34	32	)	)	PUNCT
bjp-81605	34	33	.	.	PUNCT
bjp-81605	35	1	central	central	ADJ
bjp-81605	35	2	to	to	ADP
bjp-81605	35	3	the	the	DET
bjp-81605	35	4	intrinsic	intrinsic	ADJ
bjp-81605	35	5	pathway	pathway	NOUN
bjp-81605	35	6	are	be	AUX
bjp-81605	35	7	the	the	DET
bjp-81605	35	8	bcl-2	bcl-2	PUNCT
bjp-81605	35	9	family	family	NOUN
bjp-81605	35	10	proteins	protein	NOUN
bjp-81605	35	11	,	,	PUNCT
bjp-81605	35	12	which	which	PRON
bjp-81605	35	13	function	function	VERB
bjp-81605	35	14	as	as	ADP
bjp-81605	35	15	critical	critical	ADJ
bjp-81605	35	16	regulators	regulator	NOUN
bjp-81605	35	17	of	of	ADP
bjp-81605	35	18	cell	cell	NOUN
bjp-81605	35	19	survival	survival	NOUN
bjp-81605	35	20	and	and	CCONJ
bjp-81605	35	21	mitochondrial	mitochondrial	ADJ
bjp-81605	35	22	-	-	PUNCT
bjp-81605	35	23	mediated	mediate	VERB
bjp-81605	35	24	apoptosis	apoptosis	NOUN
bjp-81605	35	25	.	.	PUNCT
bjp-81605	36	1	recent	recent	ADJ
bjp-81605	36	2	investigations	investigation	NOUN
bjp-81605	36	3	have	have	AUX
bjp-81605	36	4	further	far	ADV
bjp-81605	36	5	expanded	expand	VERB
bjp-81605	36	6	the	the	DET
bjp-81605	36	7	scope	scope	NOUN
bjp-81605	36	8	of	of	ADP
bjp-81605	36	9	targeted	target	VERB
bjp-81605	36	10	therapies	therapy	NOUN
bjp-81605	36	11	by	by	ADP
bjp-81605	36	12	focusing	focus	VERB
bjp-81605	36	13	on	on	ADP
bjp-81605	36	14	the	the	DET
bjp-81605	36	15	bcl-2	bcl-2	PUNCT
bjp-81605	36	16	protein	protein	NOUN
bjp-81605	36	17	family	family	NOUN
bjp-81605	36	18	,	,	PUNCT
bjp-81605	36	19	which	which	PRON
bjp-81605	36	20	also	also	ADV
bjp-81605	36	21	acts	act	VERB
bjp-81605	36	22	as	as	ADP
bjp-81605	36	23	a	a	DET
bjp-81605	36	24	proto	proto	NOUN
bjp-81605	36	25	-	-	PUNCT
bjp-81605	36	26	oncogene	oncogene	NOUN
bjp-81605	36	27	and	and	CCONJ
bjp-81605	36	28	an	an	DET
bjp-81605	36	29	integral	integral	ADJ
bjp-81605	36	30	membrane	membrane	NOUN
bjp-81605	36	31	protein	protein	NOUN
bjp-81605	36	32	involved	involve	VERB
bjp-81605	36	33	in	in	ADP
bjp-81605	36	34	tumor	tumor	NOUN
bjp-81605	36	35	progression	progression	NOUN
bjp-81605	36	36	.	.	PUNCT
bjp-81605	37	1	based	base	VERB
bjp-81605	37	2	on	on	ADP
bjp-81605	37	3	both	both	CCONJ
bjp-81605	37	4	in	in	ADP
bjp-81605	37	5	vitro	vitro	X
bjp-81605	37	6	and	and	CCONJ
bjp-81605	37	7	in	in	ADP
bjp-81605	37	8	vivo	vivo	ADJ
bjp-81605	37	9	findings	finding	NOUN
bjp-81605	37	10	,	,	PUNCT
bjp-81605	37	11	novel	novel	ADJ
bjp-81605	37	12	peptides	peptide	NOUN
bjp-81605	37	13	targeting	target	VERB
bjp-81605	37	14	vascular	vascular	ADJ
bjp-81605	37	15	endothelial	endothelial	ADJ
bjp-81605	37	16	growth	growth	NOUN
bjp-81605	37	17	factor	factor	NOUN
bjp-81605	37	18	receptors	receptor	NOUN
bjp-81605	37	19	,	,	PUNCT
bjp-81605	37	20	such	such	ADJ
bjp-81605	37	21	as	as	ADP
bjp-81605	37	22	vgb4	vgb4	NOUN
bjp-81605	37	23	,	,	PUNCT
bjp-81605	37	24	have	have	AUX
bjp-81605	37	25	been	be	AUX
bjp-81605	37	26	developed	develop	VERB
bjp-81605	37	27	to	to	PART
bjp-81605	37	28	specifically	specifically	ADV
bjp-81605	37	29	inhibit	inhibit	VERB
bjp-81605	37	30	vegfr1	vegfr1	NOUN
bjp-81605	37	31	and	and	CCONJ
bjp-81605	37	32	vegfr2	vegfr2	NOUN
bjp-81605	37	33	signaling	signal	VERB
bjp-81605	37	34	pathways	pathway	NOUN
bjp-81605	37	35	(	(	PUNCT
bjp-81605	37	36	behelgardi	behelgardi	PROPN
bjp-81605	37	37	et	et	PROPN
bjp-81605	37	38	al	al	PROPN
bjp-81605	37	39	.	.	PROPN
bjp-81605	37	40	,	,	PUNCT
bjp-81605	37	41	2013	2013	NUM
bjp-81605	37	42	)	)	PUNCT
bjp-81605	37	43	.	.	PUNCT
bjp-81605	38	1	notably	notably	ADV
bjp-81605	38	2	,	,	PUNCT
bjp-81605	38	3	the	the	DET
bjp-81605	38	4	vgbe	vgbe	NOUN
bjp-81605	38	5	peptide	peptide	NOUN
bjp-81605	38	6	demonstrated	demonstrate	VERB
bjp-81605	38	7	potent	potent	ADJ
bjp-81605	38	8	anti	anti	ADJ
bjp-81605	38	9	-	-	ADJ
bjp-81605	38	10	angiogenic	angiogenic	ADJ
bjp-81605	38	11	properties	property	NOUN
bjp-81605	38	12	by	by	ADP
bjp-81605	38	13	impairing	impair	VERB
bjp-81605	38	14	human	human	ADJ
bjp-81605	38	15	umbilical	umbilical	ADJ
bjp-81605	38	16	vein	vein	ADJ
bjp-81605	38	17	endothelial	endothelial	ADJ
bjp-81605	38	18	cell	cell	NOUN
bjp-81605	38	19	(	(	PUNCT
bjp-81605	38	20	huvec	huvec	NOUN
bjp-81605	38	21	)	)	PUNCT
bjp-81605	38	22	colony	colony	NOUN
bjp-81605	38	23	formation	formation	NOUN
bjp-81605	38	24	,	,	PUNCT
bjp-81605	38	25	invasion	invasion	NOUN
bjp-81605	38	26	,	,	PUNCT
bjp-81605	38	27	migration	migration	NOUN
bjp-81605	38	28	,	,	PUNCT
bjp-81605	38	29	and	and	CCONJ
bjp-81605	38	30	differentiation	differentiation	NOUN
bjp-81605	38	31	.	.	PUNCT
bjp-81605	39	1	the	the	DET
bjp-81605	39	2	overarching	overarching	ADJ
bjp-81605	39	3	aim	aim	NOUN
bjp-81605	39	4	of	of	ADP
bjp-81605	39	5	these	these	DET
bjp-81605	39	6	approaches	approach	NOUN
bjp-81605	39	7	is	be	AUX
bjp-81605	39	8	to	to	PART
bjp-81605	39	9	develop	develop	VERB
bjp-81605	39	10	targeted	target	VERB
bjp-81605	39	11	anti	anti	ADJ
bjp-81605	39	12	-	-	ADJ
bjp-81605	39	13	vegfr1	vegfr1	ADJ
bjp-81605	39	14	peptides	peptide	NOUN
bjp-81605	39	15	with	with	ADP
bjp-81605	39	16	therapeutic	therapeutic	ADJ
bjp-81605	39	17	potential	potential	NOUN
bjp-81605	39	18	for	for	ADP
bjp-81605	39	19	the	the	DET
bjp-81605	39	20	cancer	cancer	NOUN
bjp-81605	39	21	.	.	PUNCT
bjp-81605	40	1	materials	material	NOUN
bjp-81605	40	2	and	and	CCONJ
bjp-81605	40	3	methods	method	NOUN
bjp-81605	40	4	chemicals	chemical	VERB
bjp-81605	40	5	penicillin	penicillin	NOUN
bjp-81605	40	6	-	-	PUNCT
bjp-81605	40	7	streptomycin	streptomycin	PROPN
bjp-81605	40	8	(	(	PUNCT
bjp-81605	40	9	15140163	15140163	NUM
bjp-81605	40	10	)	)	PUNCT
bjp-81605	40	11	,	,	PUNCT
bjp-81605	40	12	dpbs	dpb	NOUN
bjp-81605	40	13	(	(	PUNCT
bjp-81605	40	14	10010023	10010023	NUM
bjp-81605	40	15	)	)	PUNCT
bjp-81605	40	16	,	,	PUNCT
bjp-81605	40	17	a4766801	a4766801	ADV
bjp-81605	40	18	)	)	PUNCT
bjp-81605	40	19	,	,	PUNCT
bjp-81605	40	20	dmem	dmem	VERB
bjp-81605	40	21	high	high	ADJ
bjp-81605	40	22	glucose	glucose	NOUN
bjp-81605	40	23	(	(	PUNCT
bjp-81605	40	24	11965118	11965118	NUM
bjp-81605	40	25	)	)	PUNCT
bjp-81605	40	26	,	,	PUNCT
bjp-81605	40	27	were	be	AUX
bjp-81605	40	28	purchased	purchase	VERB
bjp-81605	40	29	from	from	ADP
bjp-81605	40	30	thermo	thermo	NOUN
bjp-81605	40	31	scientific	scientific	PROPN
bjp-81605	40	32	,	,	PUNCT
bjp-81605	40	33	usa	usa	PROPN
bjp-81605	40	34	,	,	PUNCT
bjp-81605	40	35	and	and	CCONJ
bjp-81605	40	36	the	the	DET
bjp-81605	40	37	annexin	annexin	NOUN
bjp-81605	40	38	v	v	NOUN
bjp-81605	40	39	-	-	PUNCT
bjp-81605	40	40	fitc	fitc	NOUN
bjp-81605	40	41	kit	kit	NOUN
bjp-81605	40	42	(	(	PUNCT
bjp-81605	40	43	im3546	im3546	PROPN
bjp-81605	40	44	)	)	PUNCT
bjp-81605	40	45	from	from	ADP
bjp-81605	40	46	beckman	beckman	PROPN
bjp-81605	40	47	coulter	coulter	PROPN
bjp-81605	40	48	life	life	PROPN
bjp-81605	40	49	science	science	PROPN
bjp-81605	40	50	,	,	PUNCT
bjp-81605	40	51	usa	usa	PROPN
bjp-81605	40	52	.	.	PUNCT
bjp-81605	41	1	the	the	DET
bjp-81605	41	2	antibodies	antibody	NOUN
bjp-81605	41	3	cytochrome	cytochrome	NOUN
bjp-81605	41	4	c	c	NOUN
bjp-81605	41	5	(	(	PUNCT
bjp-81605	41	6	ab133504	ab133504	PROPN
bjp-81605	41	7	)	)	PUNCT
bjp-81605	41	8	,	,	PUNCT
bjp-81605	41	9	anti	anti	ADJ
bjp-81605	41	10	-	-	ADJ
bjp-81605	41	11	bax	bax	ADJ
bjp-81605	41	12	(	(	PUNCT
bjp-81605	41	13	ab182733	ab182733	PROPN
bjp-81605	41	14	)	)	PUNCT
bjp-81605	41	15	,	,	PUNCT
bjp-81605	41	16	anti	anti	ADJ
bjp-81605	41	17	-	-	ADJ
bjp-81605	41	18	bcl-2	bcl-2	ADJ
bjp-81605	41	19	(	(	PUNCT
bjp-81605	41	20	ab32124	ab32124	NOUN
bjp-81605	41	21	)	)	PUNCT
bjp-81605	41	22	,	,	PUNCT
bjp-81605	41	23	anti	anti	ADJ
bjp-81605	41	24	-	-	ADJ
bjp-81605	41	25	β	β	ADJ
bjp-81605	41	26	-	-	PUNCT
bjp-81605	41	27	actin	actin	ADJ
bjp-81605	41	28	antibody	antibody	NOUN
bjp-81605	41	29	-	-	PUNCT
bjp-81605	41	30	loading	loading	NOUN
bjp-81605	41	31	control	control	NOUN
bjp-81605	41	32	(	(	PUNCT
bjp-81605	41	33	ab8226	ab8226	PROPN
bjp-81605	41	34	)	)	PUNCT
bjp-81605	41	35	,	,	PUNCT
bjp-81605	41	36	anti	anti	ADJ
bjp-81605	41	37	-	-	ADJ
bjp-81605	41	38	p21	p21	ADJ
bjp-81605	41	39	,	,	PUNCT
bjp-81605	41	40	anti	anti	NOUN
bjp-81605	41	41	-	-	NOUN
bjp-81605	41	42	cyclind1	cyclind1	NOUN
bjp-81605	41	43	(	(	PUNCT
bjp-81605	41	44	ab26	ab26	PROPN
bjp-81605	41	45	)	)	PUNCT
bjp-81605	41	46	,	,	PUNCT
bjp-81605	41	47	anti	anti	ADJ
bjp-81605	41	48	-	-	ADJ
bjp-81605	41	49	pi3k	pi3k	ADJ
bjp-81605	41	50	,	,	PUNCT
bjp-81605	41	51	anti	anti	ADJ
bjp-81605	41	52	-	-	ADJ
bjp-81605	41	53	erk1/2	erk1/2	ADJ
bjp-81605	41	54	,	,	PUNCT
bjp-81605	41	55	and	and	CCONJ
bjp-81605	41	56	anti	anti	ADJ
bjp-81605	41	57	-	-	ADJ
bjp-81605	41	58	jnk1/2	jnk1/2	ADJ
bjp-81605	41	59	(	(	PUNCT
bjp-81605	41	60	abeam	abeam	PROPN
bjp-81605	41	61	cambridge	cambridge	PROPN
bjp-81605	41	62	,	,	PUNCT
bjp-81605	41	63	uk	uk	PROPN
bjp-81605	41	64	)	)	PUNCT
bjp-81605	41	65	were	be	AUX
bjp-81605	41	66	purchased	purchase	VERB
bjp-81605	41	67	.	.	PUNCT
bjp-81605	42	1	national	national	ADJ
bjp-81605	42	2	centre	centre	NOUN
bjp-81605	42	3	for	for	ADP
bjp-81605	42	4	cell	cell	NOUN
bjp-81605	42	5	science	science	NOUN
bjp-81605	42	6	,	,	PUNCT
bjp-81605	42	7	pune	pune	NOUN
bjp-81605	42	8	,	,	PUNCT
bjp-81605	42	9	india	india	PROPN
bjp-81605	42	10	,	,	PUNCT
bjp-81605	42	11	provided	provide	VERB
bjp-81605	42	12	colorectal	colorectal	ADJ
bjp-81605	42	13	cancer	cancer	NOUN
bjp-81605	42	14	cell	cell	NOUN
bjp-81605	42	15	lines	line	NOUN
bjp-81605	42	16	.	.	PUNCT
bjp-81605	43	1	crt2	crt2	PROPN
bjp-81605	43	2	peptide	peptide	ADJ
bjp-81605	43	3	synthesis	synthesis	NOUN
bjp-81605	43	4	the	the	DET
bjp-81605	43	5	crt2	crt2	PROPN
bjp-81605	43	6	peptide	peptide	NOUN
bjp-81605	43	7	(	(	PUNCT
bjp-81605	43	8	vklrsllcsrmmrmmrrm	vklrsllcsrmmrmmrrm	NOUN
bjp-81605	43	9	-	-	PUNCT
bjp-81605	43	10	oh	oh	NOUN
bjp-81605	43	11	)	)	PUNCT
bjp-81605	43	12	was	be	AUX
bjp-81605	43	13	synthesized	synthesize	VERB
bjp-81605	43	14	using	use	VERB
bjp-81605	43	15	fmoc	fmoc	NOUN
bjp-81605	43	16	-	-	PUNCT
bjp-81605	43	17	based	base	VERB
bjp-81605	43	18	solid	solid	ADJ
bjp-81605	43	19	-	-	PUNCT
bjp-81605	43	20	phase	phase	NOUN
bjp-81605	43	21	peptide	peptide	ADJ
bjp-81605	43	22	synthesis	synthesis	NOUN
bjp-81605	43	23	on	on	ADP
bjp-81605	43	24	rink	rink	NOUN
bjp-81605	43	25	amide	amide	NOUN
bjp-81605	43	26	resin	resin	NOUN
bjp-81605	43	27	.	.	PUNCT
bjp-81605	44	1	standard	standard	ADJ
bjp-81605	44	2	coupling	couple	VERB
bjp-81605	44	3	protocols	protocol	NOUN
bjp-81605	44	4	were	be	AUX
bjp-81605	44	5	followed	follow	VERB
bjp-81605	44	6	(	(	PUNCT
bjp-81605	44	7	yoganantham	yoganantham	PROPN
bjp-81605	44	8	et	et	PROPN
bjp-81605	44	9	al	al	PROPN
bjp-81605	44	10	.	.	PROPN
bjp-81605	44	11	2023	2023	NUM
bjp-81605	44	12	)	)	PUNCT
bjp-81605	44	13	.	.	PUNCT
bjp-81605	45	1	after	after	ADP
bjp-81605	45	2	assembly	assembly	NOUN
bjp-81605	45	3	,	,	PUNCT
bjp-81605	45	4	the	the	DET
bjp-81605	45	5	peptide	peptide	NOUN
bjp-81605	45	6	was	be	AUX
bjp-81605	45	7	cleaved	cleave	VERB
bjp-81605	45	8	from	from	ADP
bjp-81605	45	9	the	the	DET
bjp-81605	45	10	resin	resin	NOUN
bjp-81605	45	11	using	use	VERB
bjp-81605	45	12	a	a	DET
bjp-81605	45	13	trifluoroacetic	trifluoroacetic	ADJ
bjp-81605	45	14	acid	acid	NOUN
bjp-81605	45	15	cleavage	cleavage	NOUN
bjp-81605	45	16	mixture	mixture	NOUN
bjp-81605	45	17	and	and	CCONJ
bjp-81605	45	18	precipitated	precipitate	VERB
bjp-81605	45	19	with	with	ADP
bjp-81605	45	20	cold	cold	ADJ
bjp-81605	45	21	diethyl	diethyl	NOUN
bjp-81605	45	22	ether	ether	NOUN
bjp-81605	45	23	.	.	PUNCT
bjp-81605	46	1	the	the	DET
bjp-81605	46	2	crude	crude	ADJ
bjp-81605	46	3	peptide	peptide	NOUN
bjp-81605	46	4	was	be	AUX
bjp-81605	46	5	then	then	ADV
bjp-81605	46	6	purified	purify	VERB
bjp-81605	46	7	using	use	VERB
bjp-81605	46	8	ultra	ultra	ADJ
bjp-81605	46	9	-	-	ADJ
bjp-81605	46	10	performance	performance	NOUN
bjp-81605	46	11	liquid	liquid	ADJ
bjp-81605	46	12	chromatography	chromatography	NOUN
bjp-81605	46	13	with	with	ADP
bjp-81605	46	14	a	a	DET
bjp-81605	46	15	waters	water	NOUN
bjp-81605	46	16	nano	nano	NOUN
bjp-81605	46	17	quality	quality	NOUN
bjp-81605	46	18	empower-2.0	empower-2.0	NOUN
bjp-81605	46	19	system	system	NOUN
bjp-81605	46	20	.	.	PUNCT
bjp-81605	47	1	the	the	DET
bjp-81605	47	2	final	final	ADJ
bjp-81605	47	3	product	product	NOUN
bjp-81605	47	4	exhibited	exhibit	VERB
bjp-81605	47	5	a	a	DET
bjp-81605	47	6	purity	purity	NOUN
bjp-81605	47	7	of	of	ADP
bjp-81605	47	8	95	95	NUM
bjp-81605	47	9	%	%	NOUN
bjp-81605	47	10	,	,	PUNCT
bjp-81605	47	11	and	and	CCONJ
bjp-81605	47	12	its	its	PRON
bjp-81605	47	13	molecular	molecular	ADJ
bjp-81605	47	14	weight	weight	NOUN
bjp-81605	47	15	was	be	AUX
bjp-81605	47	16	confirmed	confirm	VERB
bjp-81605	47	17	using	use	VERB
bjp-81605	47	18	lc	lc	NOUN
bjp-81605	47	19	-	-	PUNCT
bjp-81605	47	20	ms/	ms/	NOUN
bjp-81605	47	21	ms	ms	ADJ
bjp-81605	47	22	analysis	analysis	NOUN
bjp-81605	47	23	.	.	PUNCT
bjp-81605	48	1	in	in	ADP
bjp-81605	48	2	silico	silico	NOUN
bjp-81605	48	3	structural	structural	ADJ
bjp-81605	48	4	biology	biology	NOUN
bjp-81605	48	5	the	the	DET
bjp-81605	48	6	3d	3d	NUM
bjp-81605	48	7	structure	structure	NOUN
bjp-81605	48	8	of	of	ADP
bjp-81605	48	9	the	the	DET
bjp-81605	48	10	crt2	crt2	PROPN
bjp-81605	48	11	peptide	peptide	NOUN
bjp-81605	48	12	was	be	AUX
bjp-81605	48	13	predicted	predict	VERB
bjp-81605	48	14	using	use	VERB
bjp-81605	48	15	the	the	DET
bjp-81605	48	16	pep	pep	NOUN
bjp-81605	48	17	-	-	PUNCT
bjp-81605	48	18	fold3	fold3	ADJ
bjp-81605	48	19	server	server	NOUN
bjp-81605	48	20	.	.	PUNCT
bjp-81605	48	21	ligand	ligand	PROPN
bjp-81605	48	22	conformations	conformation	NOUN
bjp-81605	48	23	were	be	AUX
bjp-81605	48	24	generated	generate	VERB
bjp-81605	48	25	and	and	CCONJ
bjp-81605	48	26	optimized	optimize	VERB
bjp-81605	48	27	using	use	VERB
bjp-81605	48	28	the	the	DET
bjp-81605	48	29	ligprep	ligprep	NOUN
bjp-81605	48	30	module	module	NOUN
bjp-81605	48	31	of	of	ADP
bjp-81605	48	32	schrödinger	schrödinger	NOUN
bjp-81605	48	33	.	.	PUNCT
bjp-81605	49	1	the	the	DET
bjp-81605	49	2	crystal	crystal	NOUN
bjp-81605	49	3	structure	structure	NOUN
bjp-81605	49	4	of	of	ADP
bjp-81605	49	5	vegfr1	vegfr1	NOUN
bjp-81605	49	6	(	(	PUNCT
bjp-81605	49	7	pdb	pdb	PROPN
bjp-81605	49	8	i	i	PROPN
bjp-81605	49	9	d	d	PROPN
bjp-81605	49	10	:	:	PUNCT
bjp-81605	49	11	2xac	2xac	NUM
bjp-81605	49	12	)	)	PUNCT
bjp-81605	49	13	was	be	AUX
bjp-81605	49	14	retrieved	retrieve	VERB
bjp-81605	49	15	from	from	ADP
bjp-81605	49	16	the	the	DET
bjp-81605	49	17	protein	protein	NOUN
bjp-81605	49	18	data	datum	NOUN
bjp-81605	49	19	bank	bank	NOUN
bjp-81605	49	20	and	and	CCONJ
bjp-81605	49	21	prepared	prepare	VERB
bjp-81605	49	22	using	use	VERB
bjp-81605	49	23	the	the	DET
bjp-81605	49	24	protein	protein	NOUN
bjp-81605	49	25	preparation	preparation	NOUN
bjp-81605	49	26	wizard	wizard	ADJ
bjp-81605	49	27	software	software	NOUN
bjp-81605	49	28	.	.	PUNCT
bjp-81605	50	1	docking	dock	VERB
bjp-81605	50	2	grids	grid	NOUN
bjp-81605	50	3	of	of	ADP
bjp-81605	50	4	30	30	NUM
bjp-81605	50	5	å	å	PROPN
bjp-81605	50	6	×	×	NOUN
bjp-81605	50	7	10	10	NUM
bjp-81605	50	8	å	å	NOUN
bjp-81605	50	9	were	be	AUX
bjp-81605	50	10	generated	generate	VERB
bjp-81605	50	11	around	around	ADP
bjp-81605	50	12	the	the	DET
bjp-81605	50	13	co	co	ADJ
bjp-81605	50	14	-	-	ADJ
bjp-81605	50	15	crystallized	crystallize	VERB
bjp-81605	50	16	ligand	ligand	NOUN
bjp-81605	50	17	-	-	PUNCT
bjp-81605	50	18	binding	bind	VERB
bjp-81605	50	19	site	site	NOUN
bjp-81605	50	20	.	.	PUNCT
bjp-81605	51	1	veg3	veg3	PROPN
bjp-81605	51	2	,	,	PUNCT
bjp-81605	51	3	a	a	DET
bjp-81605	51	4	known	know	VERB
bjp-81605	51	5	vegfr1	vegfr1	NOUN
bjp-81605	51	6	inhibitor	inhibitor	NOUN
bjp-81605	51	7	,	,	PUNCT
bjp-81605	51	8	was	be	AUX
bjp-81605	51	9	redocked	redocke	VERB
bjp-81605	51	10	to	to	PART
bjp-81605	51	11	validate	validate	VERB
bjp-81605	51	12	the	the	DET
bjp-81605	51	13	receptor	receptor	NOUN
bjp-81605	51	14	grid	grid	NOUN
bjp-81605	51	15	and	and	CCONJ
bjp-81605	51	16	preserve	preserve	VERB
bjp-81605	51	17	its	its	PRON
bjp-81605	51	18	native	native	ADJ
bjp-81605	51	19	interaction	interaction	NOUN
bjp-81605	51	20	profile	profile	NOUN
bjp-81605	51	21	.	.	PUNCT
bjp-81605	52	1	the	the	DET
bjp-81605	52	2	crt2	crt2	PROPN
bjp-81605	52	3	peptide	peptide	NOUN
bjp-81605	52	4	was	be	AUX
bjp-81605	52	5	docked	dock	VERB
bjp-81605	52	6	using	use	VERB
bjp-81605	52	7	the	the	DET
bjp-81605	52	8	cluspro	cluspro	ADJ
bjp-81605	52	9	2.0	2.0	NUM
bjp-81605	52	10	server	server	NOUN
bjp-81605	52	11	,	,	PUNCT
bjp-81605	52	12	and	and	CCONJ
bjp-81605	52	13	the	the	DET
bjp-81605	52	14	top	top	ADJ
bjp-81605	52	15	ten	ten	NUM
bjp-81605	52	16	docked	docked	ADJ
bjp-81605	52	17	conformations	conformation	NOUN
bjp-81605	52	18	were	be	AUX
bjp-81605	52	19	selected	select	VERB
bjp-81605	52	20	based	base	VERB
bjp-81605	52	21	on	on	ADP
bjp-81605	52	22	the	the	DET
bjp-81605	52	23	docking	docking	NOUN
bjp-81605	52	24	energy	energy	NOUN
bjp-81605	52	25	and	and	CCONJ
bjp-81605	52	26	structural	structural	ADJ
bjp-81605	52	27	alignment	alignment	NOUN
bjp-81605	52	28	.	.	PUNCT
bjp-81605	53	1	side	side	NOUN
bjp-81605	53	2	-	-	PUNCT
bjp-81605	53	3	chain	chain	NOUN
bjp-81605	53	4	refinement	refinement	NOUN
bjp-81605	53	5	was	be	AUX
bjp-81605	53	6	applied	apply	VERB
bjp-81605	53	7	,	,	PUNCT
bjp-81605	53	8	and	and	CCONJ
bjp-81605	53	9	complexes	complex	NOUN
bjp-81605	53	10	with	with	ADP
bjp-81605	53	11	low	low	ADJ
bjp-81605	53	12	binding	bind	VERB
bjp-81605	53	13	energies	energy	NOUN
bjp-81605	53	14	were	be	AUX
bjp-81605	53	15	considered	consider	VERB
bjp-81605	53	16	for	for	ADP
bjp-81605	53	17	further	further	ADJ
bjp-81605	53	18	analyses	analysis	NOUN
bjp-81605	53	19	.	.	PUNCT
bjp-81605	54	1	protein	protein	NOUN
bjp-81605	54	2	-	-	PUNCT
bjp-81605	54	3	peptide	peptide	NOUN
bjp-81605	54	4	interactions	interaction	NOUN
bjp-81605	54	5	were	be	AUX
bjp-81605	54	6	visualized	visualize	VERB
bjp-81605	54	7	and	and	CCONJ
bjp-81605	54	8	analyzed	analyze	VERB
bjp-81605	54	9	using	use	VERB
bjp-81605	54	10	pymol	pymol	PROPN
bjp-81605	54	11	and	and	CCONJ
bjp-81605	54	12	ligplot+	ligplot+	PROPN
bjp-81605	54	13	.	.	PUNCT
bjp-81605	55	1	the	the	DET
bjp-81605	55	2	missing	miss	VERB
bjp-81605	55	3	residues	residue	NOUN
bjp-81605	55	4	(	(	PUNCT
bjp-81605	55	5	val990	val990	PROPN
bjp-81605	55	6	–	–	PUNCT
bjp-81605	55	7	leu995	leu995	PROPN
bjp-81605	55	8	)	)	PUNCT
bjp-81605	55	9	in	in	ADP
bjp-81605	55	10	vegfr1	vegfr1	NOUN
bjp-81605	55	11	were	be	AUX
bjp-81605	55	12	modeled	model	VERB
bjp-81605	55	13	using	use	VERB
bjp-81605	55	14	the	the	DET
bjp-81605	55	15	prime	prime	ADJ
bjp-81605	55	16	module	module	NOUN
bjp-81605	55	17	.	.	PUNCT
bjp-81605	56	1	molecular	molecular	ADJ
bjp-81605	56	2	dynamics	dynamic	NOUN
bjp-81605	56	3	simulations	simulation	NOUN
bjp-81605	56	4	were	be	AUX
bjp-81605	56	5	conducted	conduct	VERB
bjp-81605	56	6	using	use	VERB
bjp-81605	56	7	amber14	amber14	NOUN
bjp-81605	56	8	with	with	ADP
bjp-81605	56	9	the	the	DET
bjp-81605	56	10	ff99sb	ff99sb	PROPN
bjp-81605	56	11	and	and	CCONJ
bjp-81605	56	12	gaff	gaff	NOUN
bjp-81605	56	13	force	force	NOUN
bjp-81605	56	14	fields	field	NOUN
bjp-81605	56	15	.	.	PUNCT
bjp-81605	57	1	the	the	DET
bjp-81605	57	2	systems	system	NOUN
bjp-81605	57	3	were	be	AUX
bjp-81605	57	4	neutralized	neutralize	VERB
bjp-81605	57	5	with	with	ADP
bjp-81605	57	6	counter	counter	ADJ
bjp-81605	57	7	ions	ion	NOUN
bjp-81605	57	8	and	and	CCONJ
bjp-81605	57	9	solvated	solvate	VERB
bjp-81605	57	10	in	in	ADP
bjp-81605	57	11	an	an	DET
bjp-81605	57	12	8	8	NUM
bjp-81605	57	13	å	å	PROPN
bjp-81605	57	14	tip3p	tip3p	ADP
bjp-81605	57	15	water	water	NOUN
bjp-81605	57	16	box	box	NOUN
bjp-81605	57	17	.	.	PUNCT
bjp-81605	58	1	after	after	ADP
bjp-81605	58	2	energy	energy	NOUN
bjp-81605	58	3	minimization	minimization	NOUN
bjp-81605	58	4	and	and	CCONJ
bjp-81605	58	5	equilibration	equilibration	NOUN
bjp-81605	58	6	,	,	PUNCT
bjp-81605	58	7	10	10	NUM
bjp-81605	58	8	nsec	nsec	ADJ
bjp-81605	58	9	production	production	NOUN
bjp-81605	58	10	simulations	simulation	NOUN
bjp-81605	58	11	were	be	AUX
bjp-81605	58	12	performed	perform	VERB
bjp-81605	58	13	under	under	ADP
bjp-81605	58	14	npt	npt	PROPN
bjp-81605	58	15	conditions	condition	NOUN
bjp-81605	58	16	(	(	PUNCT
bjp-81605	58	17	300	300	NUM
bjp-81605	58	18	k	k	NOUN
bjp-81605	58	19	,	,	PUNCT
bjp-81605	58	20	1	1	NUM
bjp-81605	58	21	atm	atm	NOUN
bjp-81605	58	22	)	)	PUNCT
bjp-81605	58	23	with	with	ADP
bjp-81605	58	24	a	a	DET
bjp-81605	58	25	2	2	NUM
bjp-81605	58	26	fsec	fsec	NOUN
bjp-81605	58	27	time	time	NOUN
bjp-81605	58	28	step	step	NOUN
bjp-81605	58	29	.	.	PUNCT
bjp-81605	59	1	the	the	DET
bjp-81605	59	2	shake	shake	NOUN
bjp-81605	59	3	algorithm	algorithm	NOUN
bjp-81605	59	4	,	,	PUNCT
bjp-81605	59	5	langevin	langevin	NOUN
bjp-81605	59	6	thermostat	thermostat	PROPN
bjp-81605	59	7	,	,	PUNCT
bjp-81605	59	8	and	and	CCONJ
bjp-81605	59	9	particle	particle	NOUN
bjp-81605	59	10	mesh	mesh	PROPN
bjp-81605	59	11	ewald	ewald	PROPN
bjp-81605	59	12	method	method	NOUN
bjp-81605	59	13	were	be	AUX
bjp-81605	59	14	applied	apply	VERB
bjp-81605	59	15	.	.	PUNCT
bjp-81605	60	1	snapshots	snapshot	NOUN
bjp-81605	60	2	were	be	AUX
bjp-81605	60	3	recorded	record	VERB
bjp-81605	60	4	every	every	DET
bjp-81605	60	5	10	10	NUM
bjp-81605	60	6	psec	psec	NOUN
bjp-81605	60	7	for	for	ADP
bjp-81605	60	8	each	each	DET
bjp-81605	60	9	trajectory	trajectory	NOUN
bjp-81605	60	10	.	.	PUNCT
bjp-81605	61	1	the	the	DET
bjp-81605	61	2	binding	bind	VERB
bjp-81605	61	3	free	free	ADJ
bjp-81605	61	4	energy	energy	NOUN
bjp-81605	61	5	was	be	AUX
bjp-81605	61	6	calculated	calculate	VERB
bjp-81605	61	7	using	use	VERB
bjp-81605	61	8	the	the	DET
bjp-81605	61	9	mm	mm	NOUN
bjp-81605	61	10	-	-	PUNCT
bjp-81605	61	11	pbsa	pbsa	NOUN
bjp-81605	61	12	method	method	NOUN
bjp-81605	61	13	from	from	ADP
bjp-81605	61	14	the	the	DET
bjp-81605	61	15	final	final	ADJ
bjp-81605	61	16	100	100	NUM
bjp-81605	61	17	nsec	nsec	ADJ
bjp-81605	61	18	trajectory	trajectory	NOUN
bjp-81605	61	19	data	datum	NOUN
bjp-81605	61	20	.	.	PUNCT
bjp-81605	62	1	cpptraj	cpptraj	PROPN
bjp-81605	62	2	,	,	PUNCT
bjp-81605	62	3	vmd	vmd	PROPN
bjp-81605	62	4	,	,	PUNCT
bjp-81605	62	5	and	and	CCONJ
bjp-81605	62	6	pymol	pymol	NOUN
bjp-81605	62	7	were	be	AUX
bjp-81605	62	8	used	use	VERB
bjp-81605	62	9	for	for	ADP
bjp-81605	62	10	structural	structural	ADJ
bjp-81605	62	11	analysis	analysis	NOUN
bjp-81605	62	12	and	and	CCONJ
bjp-81605	62	13	visualization	visualization	NOUN
bjp-81605	62	14	.	.	PUNCT
bjp-81605	63	1	fitc	fitc	NOUN
bjp-81605	63	2	-	-	PUNCT
bjp-81605	63	3	conjugation	conjugation	NOUN
bjp-81605	63	4	to	to	PART
bjp-81605	63	5	construct	construct	VERB
bjp-81605	63	6	a	a	DET
bjp-81605	63	7	fluorescent	fluorescent	ADJ
bjp-81605	63	8	probe	probe	NOUN
bjp-81605	63	9	,	,	PUNCT
bjp-81605	63	10	the	the	DET
bjp-81605	63	11	n	n	CCONJ
bjp-81605	63	12	-	-	PUNCT
bjp-81605	63	13	terminal	terminal	ADJ
bjp-81605	63	14	amino	amino	NOUN
bjp-81605	63	15	group	group	NOUN
bjp-81605	63	16	of	of	ADP
bjp-81605	63	17	the	the	DET
bjp-81605	63	18	peptide	peptide	NOUN
bjp-81605	63	19	was	be	AUX
bjp-81605	63	20	bound	bind	VERB
bjp-81605	63	21	to	to	PART
bjp-81605	63	22	fitc	fitc	VERB
bjp-81605	63	23	.	.	PUNCT
bjp-81605	64	1	the	the	DET
bjp-81605	64	2	peptides	peptide	NOUN
bjp-81605	64	3	90	90	NUM
bjp-81605	64	4	bangladesh	bangladesh	NOUN
bjp-81605	64	5	j	j	PROPN
bjp-81605	64	6	pharmacol	pharmacol	PROPN
bjp-81605	64	7	2025	2025	NUM
bjp-81605	64	8	;	;	PUNCT
bjp-81605	64	9	20	20	NUM
bjp-81605	64	10	:	:	SYM
bjp-81605	64	11	89	89	NUM
bjp-81605	64	12	-	-	SYM
bjp-81605	64	13	100	100	NUM
bjp-81605	64	14	were	be	AUX
bjp-81605	64	15	mixed	mix	VERB
bjp-81605	64	16	with	with	ADP
bjp-81605	64	17	a	a	DET
bjp-81605	64	18	dissolved	dissolve	VERB
bjp-81605	64	19	1	1	NUM
bjp-81605	64	20	mg	mg	NUM
bjp-81605	64	21	/	/	SYM
bjp-81605	64	22	ml	ml	NOUN
bjp-81605	64	23	fitc	fitc	NOUN
bjp-81605	64	24	solution	solution	NOUN
bjp-81605	64	25	in	in	ADP
bjp-81605	64	26	dmso	dmso	NOUN
bjp-81605	64	27	(	(	PUNCT
bjp-81605	64	28	shobeiri	shobeiri	PROPN
bjp-81605	64	29	et	et	PROPN
bjp-81605	64	30	al	al	PROPN
bjp-81605	64	31	.	.	PROPN
bjp-81605	64	32	,	,	PUNCT
bjp-81605	64	33	2022	2022	NUM
bjp-81605	64	34	)	)	PUNCT
bjp-81605	64	35	.	.	PUNCT
bjp-81605	65	1	the	the	DET
bjp-81605	65	2	reactions	reaction	NOUN
bjp-81605	65	3	at	at	ADP
bjp-81605	65	4	ph	ph	PROPN
bjp-81605	65	5	8.5	8.5	NUM
bjp-81605	65	6	limited	limit	VERB
bjp-81605	65	7	the	the	DET
bjp-81605	65	8	interaction	interaction	NOUN
bjp-81605	65	9	with	with	ADP
bjp-81605	65	10	the	the	DET
bjp-81605	65	11	arginine	arginine	NOUN
bjp-81605	65	12	and	and	CCONJ
bjp-81605	65	13	lysine	lysine	NOUN
bjp-81605	65	14	side	side	NOUN
bjp-81605	65	15	groups	group	NOUN
bjp-81605	65	16	.	.	PUNCT
bjp-81605	66	1	after	after	ADP
bjp-81605	66	2	that	that	PRON
bjp-81605	66	3	,	,	PUNCT
bjp-81605	66	4	the	the	DET
bjp-81605	66	5	tube	tube	NOUN
bjp-81605	66	6	was	be	AUX
bjp-81605	66	7	covered	cover	VERB
bjp-81605	66	8	with	with	ADP
bjp-81605	66	9	foil	foil	NOUN
bjp-81605	66	10	and	and	CCONJ
bjp-81605	66	11	placed	place	VERB
bjp-81605	66	12	in	in	ADP
bjp-81605	66	13	an	an	DET
bjp-81605	66	14	incubator	incubator	NOUN
bjp-81605	66	15	at	at	ADP
bjp-81605	66	16	37	37	NUM
bjp-81605	66	17	°	°	ADP
bjp-81605	66	18	c	c	NOUN
bjp-81605	66	19	for	for	ADP
bjp-81605	66	20	90	90	NUM
bjp-81605	66	21	min	min	NOUN
bjp-81605	66	22	.	.	PUNCT
bjp-81605	67	1	the	the	DET
bjp-81605	67	2	unbound	unbound	PROPN
bjp-81605	67	3	fitc	fitc	NOUN
bjp-81605	67	4	peptides	peptide	NOUN
bjp-81605	67	5	were	be	AUX
bjp-81605	67	6	removed	remove	VERB
bjp-81605	67	7	and	and	CCONJ
bjp-81605	67	8	transferred	transfer	VERB
bjp-81605	67	9	to	to	ADP
bjp-81605	67	10	the	the	DET
bjp-81605	67	11	pbs	pbs	PROPN
bjp-81605	67	12	storage	storage	NOUN
bjp-81605	67	13	buffer	buffer	NOUN
bjp-81605	67	14	.	.	PUNCT
bjp-81605	68	1	it	it	PRON
bjp-81605	68	2	was	be	AUX
bjp-81605	68	3	placed	place	VERB
bjp-81605	68	4	on	on	ADP
bjp-81605	68	5	a	a	DET
bjp-81605	68	6	1.5	1.5	NUM
bjp-81605	68	7	x	x	SYM
bjp-81605	68	8	150	150	NUM
bjp-81605	68	9	cm	cm	NOUN
bjp-81605	68	10	sephadex	sephadex	NOUN
bjp-81605	68	11	g10	g10	PROPN
bjp-81605	68	12	column	column	NOUN
bjp-81605	68	13	that	that	PRON
bjp-81605	68	14	had	have	AUX
bjp-81605	68	15	been	be	AUX
bjp-81605	68	16	adjusted	adjust	VERB
bjp-81605	68	17	and	and	CCONJ
bjp-81605	68	18	eluted	elute	VERB
bjp-81605	68	19	with	with	ADP
bjp-81605	68	20	ph	ph	PROPN
bjp-81605	68	21	7.5	7.5	NUM
bjp-81605	68	22	pbs	pbs	NOUN
bjp-81605	68	23	(	(	PUNCT
bjp-81605	68	24	buffer	buffer	NOUN
bjp-81605	68	25	)	)	PUNCT
bjp-81605	68	26	.	.	PUNCT
bjp-81605	69	1	then	then	ADV
bjp-81605	69	2	measured	measure	VERB
bjp-81605	69	3	at	at	ADP
bjp-81605	69	4	280	280	NUM
bjp-81605	69	5	nm	nm	ADJ
bjp-81605	69	6	phase	phase	NOUN
bjp-81605	69	7	contrast	contrast	NOUN
bjp-81605	69	8	fluorescent	fluorescent	NOUN
bjp-81605	69	9	microscope	microscope	NOUN
bjp-81605	69	10	(	(	PUNCT
bjp-81605	69	11	nikon	nikon	ADJ
bjp-81605	69	12	ts-100	ts-100	NUM
bjp-81605	69	13	olympus	olympus	PROPN
bjp-81605	69	14	,	,	PUNCT
bjp-81605	69	15	japan	japan	PROPN
bjp-81605	69	16	)	)	PUNCT
bjp-81605	69	17	,	,	PUNCT
bjp-81605	69	18	the	the	DET
bjp-81605	69	19	concentration	concentration	NOUN
bjp-81605	69	20	of	of	ADP
bjp-81605	69	21	the	the	DET
bjp-81605	69	22	samples	sample	NOUN
bjp-81605	69	23	was	be	AUX
bjp-81605	69	24	calculated	calculate	VERB
bjp-81605	69	25	using	use	VERB
bjp-81605	69	26	the	the	DET
bjp-81605	69	27	formula	formula	NOUN
bjp-81605	69	28	:	:	PUNCT
bjp-81605	69	29	peptide	peptide	NOUN
bjp-81605	69	30	(	(	PUNCT
bjp-81605	69	31	mg	mg	PROPN
bjp-81605	69	32	/	/	SYM
bjp-81605	69	33	ml	ml	NOUN
bjp-81605	69	34	)	)	PUNCT
bjp-81605	69	35	=	=	SYM
bjp-81605	69	36	(	(	PUNCT
bjp-81605	69	37	a280	a280	PROPN
bjp-81605	69	38	x	x	SYM
bjp-81605	69	39	df	df	PROPN
bjp-81605	69	40	x	x	SYM
bjp-81605	69	41	mw)/e	mw)/e	NOUN
bjp-81605	69	42	,	,	PUNCT
bjp-81605	69	43	where	where	SCONJ
bjp-81605	69	44	"	"	PUNCT
bjp-81605	69	45	e	e	NOUN
bjp-81605	69	46	"	"	PUNCT
bjp-81605	69	47	denotes	denote	VERB
bjp-81605	69	48	the	the	DET
bjp-81605	69	49	molar	molar	ADJ
bjp-81605	69	50	extinction	extinction	NOUN
bjp-81605	69	51	coefficient	coefficient	NOUN
bjp-81605	69	52	of	of	ADP
bjp-81605	69	53	each	each	DET
bjp-81605	69	54	chromophore	chromophore	NOUN
bjp-81605	69	55	at	at	ADP
bjp-81605	69	56	280	280	NUM
bjp-81605	69	57	nm	nm	NOUN
bjp-81605	69	58	,	,	PUNCT
bjp-81605	69	59	df	df	PROPN
bjp-81605	69	60	denotes	denote	VERB
bjp-81605	69	61	the	the	DET
bjp-81605	69	62	dilution	dilution	NOUN
bjp-81605	69	63	factor	factor	NOUN
bjp-81605	69	64	,	,	PUNCT
bjp-81605	69	65	and	and	CCONJ
bjp-81605	69	66	mw	mw	X
bjp-81605	69	67	stands	stand	VERB
bjp-81605	69	68	for	for	ADP
bjp-81605	69	69	peptide	peptide	NOUN
bjp-81605	69	70	molecular	molecular	ADJ
bjp-81605	69	71	weight	weight	NOUN
bjp-81605	69	72	mtt	mtt	NOUN
bjp-81605	69	73	assay	assay	VERB
bjp-81605	69	74	ht-116	ht-116	PROPN
bjp-81605	69	75	cell	cell	NOUN
bjp-81605	69	76	lines	line	NOUN
bjp-81605	69	77	(	(	PUNCT
bjp-81605	69	78	1.0	1.0	NUM
bjp-81605	69	79	x	x	SYM
bjp-81605	69	80	105	105	NUM
bjp-81605	69	81	cells	cell	NOUN
bjp-81605	69	82	/	/	SYM
bjp-81605	69	83	well	well	ADV
bjp-81605	69	84	)	)	PUNCT
bjp-81605	69	85	were	be	AUX
bjp-81605	69	86	treated	treat	VERB
bjp-81605	69	87	with	with	ADP
bjp-81605	69	88	crt2	crt2	PROPN
bjp-81605	69	89	peptide	peptide	NOUN
bjp-81605	69	90	concentrations	concentration	NOUN
bjp-81605	69	91	(	(	PUNCT
bjp-81605	69	92	0	0	NUM
bjp-81605	69	93	,	,	PUNCT
bjp-81605	69	94	10	10	NUM
bjp-81605	69	95	,	,	PUNCT
bjp-81605	69	96	and	and	CCONJ
bjp-81605	69	97	20	20	NUM
bjp-81605	69	98	µm	µm	NOUN
bjp-81605	69	99	)	)	PUNCT
bjp-81605	69	100	in	in	ADP
bjp-81605	69	101	a	a	DET
bjp-81605	69	102	96well	96well	NUM
bjp-81605	69	103	plate	plate	NOUN
bjp-81605	69	104	.	.	PUNCT
bjp-81605	70	1	the	the	DET
bjp-81605	70	2	cultures	culture	NOUN
bjp-81605	70	3	were	be	AUX
bjp-81605	70	4	incubated	incubate	VERB
bjp-81605	70	5	for	for	ADP
bjp-81605	70	6	24	24	NUM
bjp-81605	70	7	to	to	PART
bjp-81605	70	8	48	48	NUM
bjp-81605	70	9	hours	hour	NOUN
bjp-81605	70	10	at	at	ADP
bjp-81605	70	11	37	37	NUM
bjp-81605	70	12	°	°	NOUN
bjp-81605	70	13	c	c	NOUN
bjp-81605	70	14	±	±	NUM
bjp-81605	70	15	0.5	0.5	NUM
bjp-81605	70	16	°	°	ADP
bjp-81605	70	17	c	c	NOUN
bjp-81605	70	18	in	in	ADP
bjp-81605	70	19	a	a	DET
bjp-81605	70	20	humid	humid	ADJ
bjp-81605	70	21	environment	environment	NOUN
bjp-81605	70	22	with	with	ADP
bjp-81605	70	23	5	5	NUM
bjp-81605	70	24	%	%	NOUN
bjp-81605	70	25	co2	co2	NOUN
bjp-81605	70	26	.	.	PUNCT
bjp-81605	71	1	administration	administration	NOUN
bjp-81605	71	2	of	of	ADP
bjp-81605	71	3	1	1	NUM
bjp-81605	71	4	mg	mg	NUM
bjp-81605	71	5	/	/	SYM
bjp-81605	71	6	ml	ml	NOUN
bjp-81605	71	7	mtt	mtt	NOUN
bjp-81605	71	8	solution	solution	NOUN
bjp-81605	71	9	was	be	AUX
bjp-81605	71	10	done	do	VERB
bjp-81605	71	11	for	for	ADP
bjp-81605	71	12	three	three	NUM
bjp-81605	71	13	hours	hour	NOUN
bjp-81605	71	14	under	under	ADP
bjp-81605	71	15	the	the	DET
bjp-81605	71	16	same	same	ADJ
bjp-81605	71	17	conditions	condition	NOUN
bjp-81605	71	18	.	.	PUNCT
bjp-81605	72	1	after	after	ADP
bjp-81605	72	2	incubation	incubation	NOUN
bjp-81605	72	3	,	,	PUNCT
bjp-81605	72	4	100	100	NUM
bjp-81605	72	5	µl	µl	NOUN
bjp-81605	72	6	of	of	ADP
bjp-81605	72	7	dmso	dmso	NOUN
bjp-81605	72	8	was	be	AUX
bjp-81605	72	9	added	add	VERB
bjp-81605	72	10	to	to	ADP
bjp-81605	72	11	each	each	DET
bjp-81605	72	12	well	well	ADV
bjp-81605	72	13	and	and	CCONJ
bjp-81605	72	14	incubated	incubate	VERB
bjp-81605	72	15	for	for	ADP
bjp-81605	72	16	another	another	DET
bjp-81605	72	17	15	15	NUM
bjp-81605	72	18	min	min	NOUN
bjp-81605	72	19	.	.	PUNCT
bjp-81605	73	1	the	the	DET
bjp-81605	73	2	color	color	NOUN
bjp-81605	73	3	intensity	intensity	NOUN
bjp-81605	73	4	of	of	ADP
bjp-81605	73	5	mtt	mtt	NOUN
bjp-81605	73	6	formazan	formazan	NOUN
bjp-81605	73	7	was	be	AUX
bjp-81605	73	8	analyzed	analyze	VERB
bjp-81605	73	9	at	at	ADP
bjp-81605	73	10	570	570	NUM
bjp-81605	73	11	to	to	PART
bjp-81605	73	12	590	590	NUM
bjp-81605	73	13	nm	nm	NOUN
bjp-81605	73	14	using	use	VERB
bjp-81605	73	15	a	a	DET
bjp-81605	73	16	multiskan	multiskan	VERB
bjp-81605	73	17	go	go	NOUN
bjp-81605	73	18	microplate	microplate	ADJ
bjp-81605	73	19	multi	multi	NOUN
bjp-81605	73	20	-	-	NOUN
bjp-81605	73	21	spectrophotometer	spectrophotometer	ADJ
bjp-81605	73	22	(	(	PUNCT
bjp-81605	73	23	thermo	thermo	NOUN
bjp-81605	73	24	scientific	scientific	NOUN
bjp-81605	73	25	,	,	PUNCT
bjp-81605	73	26	usa	usa	PROPN
bjp-81605	73	27	)	)	PUNCT
bjp-81605	73	28	.	.	PUNCT
bjp-81605	74	1	ao	ao	PROPN
bjp-81605	74	2	/	/	SYM
bjp-81605	74	3	eb	eb	PROPN
bjp-81605	74	4	morphological	morphological	ADJ
bjp-81605	74	5	assay	assay	VERB
bjp-81605	74	6	the	the	DET
bjp-81605	74	7	ao	ao	PROPN
bjp-81605	74	8	/	/	SYM
bjp-81605	74	9	eb	eb	PROPN
bjp-81605	74	10	assay	assay	PROPN
bjp-81605	74	11	was	be	AUX
bjp-81605	74	12	used	use	VERB
bjp-81605	74	13	to	to	PART
bjp-81605	74	14	examine	examine	VERB
bjp-81605	74	15	both	both	DET
bjp-81605	74	16	living	live	VERB
bjp-81605	74	17	and	and	CCONJ
bjp-81605	74	18	dead	dead	ADJ
bjp-81605	74	19	cells	cell	NOUN
bjp-81605	74	20	.	.	PUNCT
bjp-81605	75	1	this	this	DET
bjp-81605	75	2	experimental	experimental	ADJ
bjp-81605	75	3	protocol	protocol	NOUN
bjp-81605	75	4	is	be	AUX
bjp-81605	75	5	carried	carry	VERB
bjp-81605	75	6	out	out	ADP
bjp-81605	75	7	on	on	ADP
bjp-81605	75	8	crt2	crt2	PROPN
bjp-81605	75	9	cells	cell	NOUN
bjp-81605	75	10	treated	treat	VERB
bjp-81605	75	11	at	at	ADP
bjp-81605	75	12	ic50	ic50	PROPN
bjp-81605	75	13	concentrations	concentration	NOUN
bjp-81605	75	14	,	,	PUNCT
bjp-81605	75	15	as	as	ADV
bjp-81605	75	16	well	well	ADV
bjp-81605	75	17	as	as	ADP
bjp-81605	75	18	pbs	pbs	PROPN
bjp-81605	75	19	-treated	-treate	VERB
bjp-81605	75	20	cells	cell	NOUN
bjp-81605	75	21	,	,	PUNCT
bjp-81605	75	22	as	as	ADP
bjp-81605	75	23	the	the	DET
bjp-81605	75	24	control	control	NOUN
bjp-81605	75	25	group	group	NOUN
bjp-81605	75	26	.	.	PUNCT
bjp-81605	76	1	they	they	PRON
bjp-81605	76	2	were	be	AUX
bjp-81605	76	3	incubated	incubate	VERB
bjp-81605	76	4	with	with	ADP
bjp-81605	76	5	an	an	DET
bjp-81605	76	6	ao	ao	PROPN
bjp-81605	76	7	/	/	SYM
bjp-81605	76	8	eb	eb	PROPN
bjp-81605	76	9	(	(	PUNCT
bjp-81605	76	10	100	100	NUM
bjp-81605	76	11	µl	µl	PART
bjp-81605	76	12	/	/	SYM
bjp-81605	76	13	ml	ml	NOUN
bjp-81605	76	14	)	)	PUNCT
bjp-81605	76	15	cocktail	cocktail	NOUN
bjp-81605	76	16	for	for	ADP
bjp-81605	76	17	15	15	NUM
bjp-81605	76	18	min	min	NOUN
bjp-81605	76	19	(	(	PUNCT
bjp-81605	76	20	wageesha	wageesha	PROPN
bjp-81605	76	21	et	et	PROPN
bjp-81605	76	22	al	al	PROPN
bjp-81605	76	23	.	.	PROPN
bjp-81605	76	24	,	,	PUNCT
bjp-81605	76	25	2017	2017	NUM
bjp-81605	76	26	)	)	PUNCT
bjp-81605	76	27	.	.	PUNCT
bjp-81605	77	1	cell	cell	NOUN
bjp-81605	77	2	death	death	NOUN
bjp-81605	77	3	was	be	AUX
bjp-81605	77	4	observed	observe	VERB
bjp-81605	77	5	under	under	ADP
bjp-81605	77	6	a	a	DET
bjp-81605	77	7	phase	phase	NOUN
bjp-81605	77	8	-	-	PUNCT
bjp-81605	77	9	contrast	contrast	NOUN
bjp-81605	77	10	fluorescent	fluorescent	NOUN
bjp-81605	77	11	microscope	microscope	NOUN
bjp-81605	77	12	(	(	PUNCT
bjp-81605	77	13	nikon	nikon	ADJ
bjp-81605	77	14	ts-100	ts-100	NUM
bjp-81605	77	15	olympus	olympus	PROPN
bjp-81605	77	16	,	,	PUNCT
bjp-81605	77	17	japan	japan	PROPN
bjp-81605	77	18	)	)	PUNCT
bjp-81605	77	19	.	.	PUNCT
bjp-81605	78	1	apoptosis	apoptosis	NOUN
bjp-81605	78	2	and	and	CCONJ
bjp-81605	78	3	cell	cell	NOUN
bjp-81605	78	4	cycle	cycle	NOUN
bjp-81605	78	5	assay	assay	PROPN
bjp-81605	78	6	ht-116	ht-116	PROPN
bjp-81605	78	7	cells	cell	NOUN
bjp-81605	78	8	(	(	PUNCT
bjp-81605	78	9	1.5	1.5	NUM
bjp-81605	78	10	x	x	SYM
bjp-81605	78	11	105	105	NUM
bjp-81605	78	12	cells	cell	NOUN
bjp-81605	78	13	)	)	PUNCT
bjp-81605	78	14	were	be	AUX
bjp-81605	78	15	grown	grow	VERB
bjp-81605	78	16	in	in	ADP
bjp-81605	78	17	6	6	NUM
bjp-81605	78	18	-	-	PUNCT
bjp-81605	78	19	well	well	NOUN
bjp-81605	78	20	plates	plate	NOUN
bjp-81605	78	21	at	at	ADP
bjp-81605	78	22	37	37	NUM
bjp-81605	78	23	±	±	NUM
bjp-81605	78	24	0.5	0.5	NUM
bjp-81605	78	25	°	°	ADP
bjp-81605	78	26	c	c	NOUN
bjp-81605	78	27	with	with	ADP
bjp-81605	78	28	5%co2	5%co2	NUM
bjp-81605	78	29	for	for	ADP
bjp-81605	78	30	24	24	NUM
bjp-81605	78	31	hours	hour	NOUN
bjp-81605	78	32	with	with	ADP
bjp-81605	78	33	ic50	ic50	PROPN
bjp-81605	78	34	concentrations	concentration	NOUN
bjp-81605	78	35	of	of	ADP
bjp-81605	78	36	0	0	NUM
bjp-81605	78	37	,	,	PUNCT
bjp-81605	78	38	10	10	NUM
bjp-81605	78	39	,	,	PUNCT
bjp-81605	78	40	and	and	CCONJ
bjp-81605	78	41	20	20	NUM
bjp-81605	78	42	µm	µm	NOUN
bjp-81605	78	43	of	of	ADP
bjp-81605	78	44	crt2	crt2	PROPN
bjp-81605	78	45	peptide	peptide	VERB
bjp-81605	78	46	.	.	PUNCT
bjp-81605	79	1	to	to	PART
bjp-81605	79	2	illustrate	illustrate	VERB
bjp-81605	79	3	it	it	PRON
bjp-81605	79	4	briefly	briefly	ADV
bjp-81605	79	5	,	,	PUNCT
bjp-81605	79	6	the	the	DET
bjp-81605	79	7	treated	treat	VERB
bjp-81605	79	8	cells	cell	NOUN
bjp-81605	79	9	were	be	AUX
bjp-81605	79	10	trypsinized	trypsinize	VERB
bjp-81605	79	11	and	and	CCONJ
bjp-81605	79	12	then	then	ADV
bjp-81605	79	13	subjected	subject	VERB
bjp-81605	79	14	to	to	ADP
bjp-81605	79	15	a	a	DET
bjp-81605	79	16	minimum	minimum	NOUN
bjp-81605	79	17	of	of	ADP
bjp-81605	79	18	three	three	NUM
bjp-81605	79	19	ice	ice	NOUN
bjp-81605	79	20	-	-	PUNCT
bjp-81605	79	21	cold	cold	ADJ
bjp-81605	79	22	dpbs	dpb	NOUN
bjp-81605	79	23	washes	wash	NOUN
bjp-81605	79	24	.	.	PUNCT
bjp-81605	80	1	cells	cell	NOUN
bjp-81605	80	2	were	be	AUX
bjp-81605	80	3	resuspended	resuspend	VERB
bjp-81605	80	4	in	in	ADP
bjp-81605	80	5	100	100	NUM
bjp-81605	80	6	µl	µl	NOUN
bjp-81605	80	7	of	of	ADP
bjp-81605	80	8	dna	dna	NOUN
bjp-81605	80	9	binding	bind	VERB
bjp-81605	80	10	buffer	buffer	NOUN
bjp-81605	80	11	for	for	ADP
bjp-81605	80	12	5	5	NUM
bjp-81605	80	13	min	min	NOUN
bjp-81605	80	14	and	and	CCONJ
bjp-81605	80	15	then	then	ADV
bjp-81605	80	16	stained	stain	VERB
bjp-81605	80	17	with	with	ADP
bjp-81605	80	18	5	5	NUM
bjp-81605	80	19	µl	µl	NOUN
bjp-81605	80	20	of	of	ADP
bjp-81605	80	21	annexin	annexin	NOUN
bjp-81605	80	22	v	v	NOUN
bjp-81605	80	23	and	and	CCONJ
bjp-81605	80	24	10	10	NUM
bjp-81605	80	25	µl	µl	NOUN
bjp-81605	80	26	of	of	ADP
bjp-81605	80	27	pi	pi	NOUN
bjp-81605	80	28	for	for	ADP
bjp-81605	80	29	10	10	NUM
bjp-81605	80	30	min	min	NOUN
bjp-81605	80	31	at	at	ADP
bjp-81605	80	32	ambient	ambient	ADJ
bjp-81605	80	33	temperature	temperature	NOUN
bjp-81605	80	34	(	(	PUNCT
bjp-81605	80	35	25	25	NUM
bjp-81605	80	36	°	°	NUM
bjp-81605	80	37	c	c	NOUN
bjp-81605	80	38	)	)	PUNCT
bjp-81605	80	39	(	(	PUNCT
bjp-81605	80	40	ahmed	ahme	VERB
bjp-81605	80	41	,	,	PUNCT
bjp-81605	80	42	2020	2020	NUM
bjp-81605	80	43	;	;	PUNCT
bjp-81605	80	44	fantoukh	fantoukh	PROPN
bjp-81605	80	45	et	et	PROPN
bjp-81605	80	46	al	al	PROPN
bjp-81605	80	47	.	.	PROPN
bjp-81605	80	48	,	,	PUNCT
bjp-81605	80	49	2023	2023	NUM
bjp-81605	80	50	)	)	PUNCT
bjp-81605	80	51	.	.	PUNCT
bjp-81605	81	1	the	the	DET
bjp-81605	81	2	flow	flow	NOUN
bjp-81605	81	3	cytometry	cytometry	NOUN
bjp-81605	81	4	data	datum	NOUN
bjp-81605	81	5	were	be	AUX
bjp-81605	81	6	analyzed	analyze	VERB
bjp-81605	81	7	using	use	VERB
bjp-81605	81	8	a	a	DET
bjp-81605	81	9	cyto	cyto	ADJ
bjp-81605	81	10	-	-	PUNCT
bjp-81605	81	11	flex	flex	ADJ
bjp-81605	81	12	flow	flow	NOUN
bjp-81605	81	13	cytometer	cytometer	NOUN
bjp-81605	81	14	(	(	PUNCT
bjp-81605	81	15	beckman	beckman	PROPN
bjp-81605	81	16	cutler	cutler	PROPN
bjp-81605	81	17	inc	inc	PROPN
bjp-81605	81	18	.	.	PROPN
bjp-81605	81	19	,	,	PUNCT
bjp-81605	81	20	usa	usa	PROPN
bjp-81605	81	21	)	)	PUNCT
bjp-81605	81	22	.	.	PUNCT
bjp-81605	82	1	weston	weston	PROPN
bjp-81605	82	2	-	-	PUNCT
bjp-81605	82	3	blot	blot	NOUN
bjp-81605	82	4	analysis	analysis	NOUN
bjp-81605	82	5	total	total	ADJ
bjp-81605	82	6	protein	protein	NOUN
bjp-81605	82	7	was	be	AUX
bjp-81605	82	8	isolated	isolate	VERB
bjp-81605	82	9	from	from	ADP
bjp-81605	82	10	the	the	DET
bjp-81605	82	11	treated	treat	VERB
bjp-81605	82	12	ht-116	ht-116	NOUN
bjp-81605	82	13	cell	cell	NOUN
bjp-81605	82	14	lines	line	NOUN
bjp-81605	82	15	using	use	VERB
bjp-81605	82	16	a	a	DET
bjp-81605	82	17	ripa	ripa	ADJ
bjp-81605	82	18	buffer	buffer	NOUN
bjp-81605	82	19	cocktail	cocktail	NOUN
bjp-81605	82	20	.	.	PUNCT
bjp-81605	83	1	roughly	roughly	ADV
bjp-81605	83	2	1	1	NUM
bjp-81605	83	3	mg	mg	NOUN
bjp-81605	83	4	of	of	ADP
bjp-81605	83	5	the	the	DET
bjp-81605	83	6	sample	sample	NOUN
bjp-81605	83	7	was	be	AUX
bjp-81605	83	8	chopped	chop	VERB
bjp-81605	83	9	and	and	CCONJ
bjp-81605	83	10	stored	store	VERB
bjp-81605	83	11	at	at	ADP
bjp-81605	83	12	4	4	NUM
bjp-81605	83	13	°	°	ADP
bjp-81605	83	14	c	c	NOUN
bjp-81605	83	15	for	for	ADP
bjp-81605	83	16	30	30	NUM
bjp-81605	83	17	min	min	NOUN
bjp-81605	83	18	with	with	ADP
bjp-81605	83	19	a	a	DET
bjp-81605	83	20	protease	protease	NOUN
bjp-81605	83	21	cocktail	cocktail	NOUN
bjp-81605	83	22	.	.	PUNCT
bjp-81605	84	1	the	the	DET
bjp-81605	84	2	mixture	mixture	NOUN
bjp-81605	84	3	was	be	AUX
bjp-81605	84	4	centrifuged	centrifuge	VERB
bjp-81605	84	5	at	at	ADP
bjp-81605	84	6	20,000	20,000	NUM
bjp-81605	84	7	x	x	SYM
bjp-81605	84	8	g	g	NOUN
bjp-81605	84	9	for	for	ADP
bjp-81605	84	10	10	10	NUM
bjp-81605	84	11	min	min	NOUN
bjp-81605	84	12	(	(	PUNCT
bjp-81605	84	13	han	han	PROPN
bjp-81605	84	14	et	et	PROPN
bjp-81605	84	15	al	al	PROPN
bjp-81605	84	16	.	.	PROPN
bjp-81605	84	17	,	,	PUNCT
bjp-81605	84	18	2019	2019	NUM
bjp-81605	84	19	)	)	PUNCT
bjp-81605	84	20	.	.	PUNCT
bjp-81605	85	1	total	total	ADJ
bjp-81605	85	2	protein	protein	NOUN
bjp-81605	85	3	box	box	NOUN
bjp-81605	85	4	1	1	NUM
bjp-81605	85	5	:	:	PUNCT
bjp-81605	85	6	peptide	peptide	VERB
bjp-81605	85	7	binding	bind	VERB
bjp-81605	85	8	assay	assay	PROPN
bjp-81605	85	9	principle	principle	NOUN
bjp-81605	85	10	the	the	DET
bjp-81605	85	11	assay	assay	NOUN
bjp-81605	85	12	evaluates	evaluate	VERB
bjp-81605	85	13	the	the	DET
bjp-81605	85	14	binding	bind	VERB
bjp-81605	85	15	affinity	affinity	NOUN
bjp-81605	85	16	of	of	ADP
bjp-81605	85	17	fitc	fitc	NOUN
bjp-81605	85	18	-	-	PUNCT
bjp-81605	85	19	labeled	label	VERB
bjp-81605	85	20	crt2	crt2	NOUN
bjp-81605	85	21	peptide	peptide	NOUN
bjp-81605	85	22	to	to	ADP
bjp-81605	85	23	vegfr1	vegfr1	NOUN
bjp-81605	85	24	-	-	PUNCT
bjp-81605	85	25	expressing	express	VERB
bjp-81605	85	26	ht-116	ht-116	NOUN
bjp-81605	85	27	epithelial	epithelial	ADJ
bjp-81605	85	28	cells	cell	NOUN
bjp-81605	85	29	using	use	VERB
bjp-81605	85	30	flow	flow	NOUN
bjp-81605	85	31	cytometry	cytometry	NOUN
bjp-81605	85	32	and	and	CCONJ
bjp-81605	85	33	fluorescence	fluorescence	NOUN
bjp-81605	85	34	microscopy	microscopy	NOUN
bjp-81605	85	35	requirements	requirement	VERB
bjp-81605	85	36	cells	cell	NOUN
bjp-81605	85	37	and	and	CCONJ
bjp-81605	85	38	culture	culture	NOUN
bjp-81605	85	39	media	medium	NOUN
bjp-81605	85	40	:	:	PUNCT
bjp-81605	85	41	ht-116	ht-116	PROPN
bjp-81605	85	42	,	,	PUNCT
bjp-81605	85	43	dulbecco	dulbecco	NOUN
bjp-81605	85	44	’s	’s	PART
bjp-81605	85	45	modified	modify	VERB
bjp-81605	85	46	eagle	eagle	PROPN
bjp-81605	85	47	medium	medium	NOUN
bjp-81605	85	48	(	(	PUNCT
bjp-81605	85	49	dmem	dmem	ADJ
bjp-81605	85	50	)	)	PUNCT
bjp-81605	85	51	,	,	PUNCT
bjp-81605	85	52	fetal	fetal	ADJ
bjp-81605	85	53	bovine	bovine	NOUN
bjp-81605	85	54	serum	serum	NOUN
bjp-81605	85	55	(	(	PUNCT
bjp-81605	85	56	fbs	fbs	PROPN
bjp-81605	85	57	)	)	PUNCT
bjp-81605	85	58	–	–	PUNCT
bjp-81605	85	59	5	5	NUM
bjp-81605	85	60	%	%	NOUN
bjp-81605	85	61	,	,	PUNCT
bjp-81605	85	62	phosphate	phosphate	ADJ
bjp-81605	85	63	buffered	buffer	VERB
bjp-81605	85	64	saline	saline	NOUN
bjp-81605	85	65	(	(	PUNCT
bjp-81605	85	66	pbs	pbs	PROPN
bjp-81605	85	67	)	)	PUNCT
bjp-81605	85	68	and	and	CCONJ
bjp-81605	85	69	pbs	pbs	PROPN
bjp-81605	85	70	with	with	ADP
bjp-81605	85	71	0.05	0.05	NUM
bjp-81605	85	72	%	%	NOUN
bjp-81605	85	73	tween-20	tween-20	PROPN
bjp-81605	85	74	(	(	PUNCT
bjp-81605	85	75	pbs	pbs	PROPN
bjp-81605	85	76	-	-	PUNCT
bjp-81605	85	77	t	t	PROPN
bjp-81605	85	78	)	)	PUNCT
bjp-81605	85	79	fixatives	fixative	NOUN
bjp-81605	85	80	and	and	CCONJ
bjp-81605	85	81	blocking	block	VERB
bjp-81605	85	82	agents	agent	NOUN
bjp-81605	85	83	:	:	PUNCT
bjp-81605	85	84	4	4	NUM
bjp-81605	85	85	%	%	NOUN
bjp-81605	85	86	formaldehyde	formaldehyde	NOUN
bjp-81605	85	87	(	(	PUNCT
bjp-81605	85	88	for	for	ADP
bjp-81605	85	89	cell	cell	NOUN
bjp-81605	85	90	fixation	fixation	NOUN
bjp-81605	85	91	)	)	PUNCT
bjp-81605	85	92	,	,	PUNCT
bjp-81605	85	93	bovine	bovine	NOUN
bjp-81605	85	94	serum	serum	NOUN
bjp-81605	85	95	albumin	albumin	PROPN
bjp-81605	85	96	(	(	PUNCT
bjp-81605	85	97	bsa	bsa	PROPN
bjp-81605	85	98	)	)	PUNCT
bjp-81605	85	99	–	–	PUNCT
bjp-81605	85	100	1	1	NUM
bjp-81605	85	101	%	%	NOUN
bjp-81605	85	102	normal	normal	ADJ
bjp-81605	85	103	goat	goat	PROPN
bjp-81605	85	104	serum	serum	NOUN
bjp-81605	85	105	–	–	PUNCT
bjp-81605	85	106	10	10	NUM
bjp-81605	85	107	%	%	NOUN
bjp-81605	85	108	and	and	CCONJ
bjp-81605	85	109	glycine	glycine	NOUN
bjp-81605	85	110	–	–	PUNCT
bjp-81605	85	111	0.3	0.3	NUM
bjp-81605	85	112	m.	m.	NOUN
bjp-81605	85	113	antibodies	antibodie	VERB
bjp-81605	85	114	:	:	PUNCT
bjp-81605	85	115	primary	primary	ADJ
bjp-81605	85	116	antibody	antibody	NOUN
bjp-81605	85	117	against	against	ADP
bjp-81605	85	118	vegfr1	vegfr1	NOUN
bjp-81605	85	119	(	(	PUNCT
bjp-81605	85	120	mouse	mouse	NOUN
bjp-81605	85	121	monoclonal	monoclonal	NOUN
bjp-81605	85	122	)	)	PUNCT
bjp-81605	85	123	and	and	CCONJ
bjp-81605	86	1	secondary	secondary	ADJ
bjp-81605	86	2	antibody	antibody	NOUN
bjp-81605	86	3	phycoerythrin	phycoerythrin	NOUN
bjp-81605	86	4	-	-	PUNCT
bjp-81605	86	5	labeled	label	VERB
bjp-81605	86	6	anti	anti	ADJ
bjp-81605	86	7	-	-	ADJ
bjp-81605	86	8	mouse	mouse	ADJ
bjp-81605	86	9	igg	igg	PROPN
bjp-81605	86	10	.	.	PUNCT
bjp-81605	86	11	procedure	procedure	NOUN
bjp-81605	86	12	step	step	NOUN
bjp-81605	86	13	1	1	NUM
bjp-81605	86	14	:	:	PUNCT
bjp-81605	86	15	to	to	PART
bjp-81605	86	16	study	study	VERB
bjp-81605	86	17	crt2	crt2	PROPN
bjp-81605	86	18	's	's	PART
bjp-81605	86	19	ability	ability	NOUN
bjp-81605	86	20	to	to	PART
bjp-81605	86	21	interact	interact	VERB
bjp-81605	86	22	with	with	ADP
bjp-81605	86	23	epithelial	epithelial	ADJ
bjp-81605	86	24	cells	cell	NOUN
bjp-81605	86	25	ht-116	ht-116	VERB
bjp-81605	86	26	(	(	PUNCT
bjp-81605	86	27	3	3	NUM
bjp-81605	86	28	×	×	NOUN
bjp-81605	86	29	104	104	NUM
bjp-81605	86	30	cells	cell	NOUN
bjp-81605	86	31	/	/	SYM
bjp-81605	86	32	well	well	ADV
bjp-81605	86	33	)	)	PUNCT
bjp-81605	86	34	treated	treat	VERB
bjp-81605	86	35	with	with	ADP
bjp-81605	86	36	fitc	fitc	NOUN
bjp-81605	86	37	-	-	PUNCT
bjp-81605	86	38	labeled	label	VERB
bjp-81605	86	39	crt2peptide	crt2peptide	PROPN
bjp-81605	86	40	(	(	PUNCT
bjp-81605	86	41	0.35	0.35	NUM
bjp-81605	86	42	and	and	CCONJ
bjp-81605	86	43	0.75	0.75	NUM
bjp-81605	86	44	μm	μm	NUM
bjp-81605	86	45	)	)	PUNCT
bjp-81605	86	46	or	or	CCONJ
bjp-81605	86	47	fitc	fitc	NOUN
bjp-81605	86	48	labeled	label	VERB
bjp-81605	86	49	src	src	NOUN
bjp-81605	86	50	-	-	PUNCT
bjp-81605	86	51	peptide	peptide	NOUN
bjp-81605	86	52	(	(	PUNCT
bjp-81605	86	53	0.6	0.6	NUM
bjp-81605	86	54	μm	μm	NOUN
bjp-81605	86	55	)	)	PUNCT
bjp-81605	86	56	in	in	ADP
bjp-81605	86	57	dmem	dmem	ADJ
bjp-81605	86	58	media	medium	NOUN
bjp-81605	86	59	containing	contain	VERB
bjp-81605	86	60	5	5	NUM
bjp-81605	86	61	%	%	NOUN
bjp-81605	86	62	fetal	fetal	ADJ
bjp-81605	86	63	bovine	bovine	NOUN
bjp-81605	86	64	serum	serum	NOUN
bjp-81605	86	65	at	at	ADP
bjp-81605	86	66	37	37	NUM
bjp-81605	86	67	°	°	NOUN
bjp-81605	86	68	c	c	NOUN
bjp-81605	86	69	(	(	PUNCT
bjp-81605	86	70	±	±	NOUN
bjp-81605	86	71	0.5	0.5	NUM
bjp-81605	86	72	°	°	ADP
bjp-81605	86	73	c	c	NOUN
bjp-81605	86	74	)	)	PUNCT
bjp-81605	86	75	with	with	ADP
bjp-81605	86	76	5%co2	5%co2	NUM
bjp-81605	86	77	was	be	AUX
bjp-81605	86	78	humidified	humidify	VERB
bjp-81605	86	79	for	for	ADP
bjp-81605	86	80	24	24	NUM
bjp-81605	86	81	hours	hour	NOUN
bjp-81605	86	82	.	.	PUNCT
bjp-81605	87	1	step	step	NOUN
bjp-81605	87	2	2	2	NUM
bjp-81605	87	3	:	:	PUNCT
bjp-81605	87	4	following	follow	VERB
bjp-81605	87	5	three	three	NUM
bjp-81605	87	6	pbs	pbs	PROPN
bjp-81605	87	7	washes	wash	NOUN
bjp-81605	87	8	,	,	PUNCT
bjp-81605	87	9	the	the	DET
bjp-81605	87	10	cells	cell	NOUN
bjp-81605	87	11	were	be	AUX
bjp-81605	87	12	tympanized	tympanize	VERB
bjp-81605	87	13	and	and	CCONJ
bjp-81605	87	14	reconstituted	reconstitute	VERB
bjp-81605	87	15	in	in	ADP
bjp-81605	87	16	pbs	pbs	PROPN
bjp-81605	87	17	for	for	ADP
bjp-81605	87	18	flow	flow	NOUN
bjp-81605	87	19	cytometry	cytometry	NOUN
bjp-81605	87	20	analysis	analysis	NOUN
bjp-81605	87	21	(	(	PUNCT
bjp-81605	87	22	bd	bd	PROPN
bjp-81605	87	23	facs	facs	PROPN
bjp-81605	87	24	calibur	calibur	PROPN
bjp-81605	87	25	flow	flow	NOUN
bjp-81605	87	26	cytometer	cytometer	NOUN
bjp-81605	87	27	)	)	PUNCT
bjp-81605	87	28	.	.	PUNCT
bjp-81605	88	1	step	step	NOUN
bjp-81605	88	2	3	3	NUM
bjp-81605	88	3	:	:	PUNCT
bjp-81605	88	4	ht-116	ht-116	PROPN
bjp-81605	88	5	cells	cell	NOUN
bjp-81605	88	6	were	be	AUX
bjp-81605	88	7	placed	place	VERB
bjp-81605	88	8	in	in	ADP
bjp-81605	88	9	a	a	DET
bjp-81605	88	10	12	12	NUM
bjp-81605	88	11	-	-	PUNCT
bjp-81605	88	12	well	well	NOUN
bjp-81605	88	13	plate	plate	NOUN
bjp-81605	88	14	and	and	CCONJ
bjp-81605	88	15	allowed	allow	VERB
bjp-81605	88	16	to	to	PART
bjp-81605	88	17	reach	reach	VERB
bjp-81605	88	18	80	80	NUM
bjp-81605	88	19	%	%	NOUN
bjp-81605	88	20	confluence	confluence	NOUN
bjp-81605	88	21	to	to	PART
bjp-81605	88	22	evaluate	evaluate	VERB
bjp-81605	88	23	crt2	crt2	NOUN
bjp-81605	88	24	binding	bind	VERB
bjp-81605	88	25	to	to	ADP
bjp-81605	88	26	vegfr+	vegfr+	NOUN
bjp-81605	88	27	cells	cell	NOUN
bjp-81605	88	28	.	.	PUNCT
bjp-81605	89	1	step	step	NOUN
bjp-81605	89	2	4	4	NUM
bjp-81605	89	3	:	:	PUNCT
bjp-81605	89	4	after	after	ADP
bjp-81605	89	5	that	that	PRON
bjp-81605	89	6	,	,	PUNCT
bjp-81605	89	7	in	in	ADP
bjp-81605	89	8	humid	humid	ADJ
bjp-81605	89	9	conditions	condition	NOUN
bjp-81605	89	10	,	,	PUNCT
bjp-81605	89	11	treated	treat	VERB
bjp-81605	89	12	for	for	ADP
bjp-81605	89	13	24	24	NUM
bjp-81605	89	14	hours	hour	NOUN
bjp-81605	89	15	using	use	VERB
bjp-81605	89	16	various	various	ADJ
bjp-81605	89	17	doses	dose	NOUN
bjp-81605	89	18	of	of	ADP
bjp-81605	89	19	crt2	crt2	PROPN
bjp-81605	89	20	peptide	peptide	NOUN
bjp-81605	89	21	(	(	PUNCT
bjp-81605	89	22	0.35	0.35	NUM
bjp-81605	89	23	and	and	CCONJ
bjp-81605	89	24	0.75	0.75	NUM
bjp-81605	89	25	μm	μm	NUM
bjp-81605	89	26	)	)	PUNCT
bjp-81605	89	27	and	and	CCONJ
bjp-81605	89	28	scr	scr	NOUN
bjp-81605	89	29	peptide	peptide	NOUN
bjp-81605	89	30	(	(	PUNCT
bjp-81605	89	31	0.6	0.6	NUM
bjp-81605	89	32	μm	μm	NUM
bjp-81605	89	33	)	)	PUNCT
bjp-81605	89	34	.	.	PUNCT
bjp-81605	90	1	step	step	NOUN
bjp-81605	90	2	5	5	NUM
bjp-81605	90	3	:	:	PUNCT
bjp-81605	90	4	following	follow	VERB
bjp-81605	90	5	two	two	NUM
bjp-81605	90	6	pbs	pbs	PROPN
bjp-81605	90	7	-	-	PUNCT
bjp-81605	90	8	tween	tween	NOUN
bjp-81605	90	9	(	(	PUNCT
bjp-81605	90	10	0.05	0.05	NUM
bjp-81605	90	11	%	%	NOUN
bjp-81605	90	12	tween	tween	NOUN
bjp-81605	90	13	)	)	PUNCT
bjp-81605	90	14	washes	wash	NOUN
bjp-81605	90	15	in	in	ADP
bjp-81605	90	16	each	each	PRON
bjp-81605	90	17	well	well	ADV
bjp-81605	90	18	,	,	PUNCT
bjp-81605	90	19	tympanized	tympanize	VERB
bjp-81605	90	20	cells	cell	NOUN
bjp-81605	90	21	were	be	AUX
bjp-81605	90	22	fixed	fix	VERB
bjp-81605	90	23	in	in	ADP
bjp-81605	90	24	4	4	NUM
bjp-81605	90	25	%	%	NOUN
bjp-81605	90	26	formaldehyde	formaldehyde	NOUN
bjp-81605	90	27	for	for	ADP
bjp-81605	90	28	20	20	NUM
bjp-81605	90	29	min	min	NOUN
bjp-81605	90	30	at	at	ADP
bjp-81605	90	31	room	room	NOUN
bjp-81605	90	32	temperature	temperature	NOUN
bjp-81605	90	33	.	.	PUNCT
bjp-81605	91	1	step	step	NOUN
bjp-81605	91	2	6	6	NUM
bjp-81605	91	3	:	:	PUNCT
bjp-81605	91	4	a	a	DET
bjp-81605	91	5	blocking	block	VERB
bjp-81605	91	6	buffer	buffer	NOUN
bjp-81605	91	7	consisting	consist	VERB
bjp-81605	91	8	of	of	ADP
bjp-81605	91	9	1%bsa	1%bsa	NUM
bjp-81605	91	10	,	,	PUNCT
bjp-81605	91	11	10	10	NUM
bjp-81605	91	12	%	%	NOUN
bjp-81605	91	13	normal	normal	ADJ
bjp-81605	91	14	goat	goat	PROPN
bjp-81605	91	15	serum	serum	PROPN
bjp-81605	91	16	,	,	PUNCT
bjp-81605	91	17	and	and	CCONJ
bjp-81605	91	18	0.3	0.3	NUM
bjp-81605	91	19	m	m	NOUN
bjp-81605	91	20	glycine	glycine	NOUN
bjp-81605	91	21	in	in	ADP
bjp-81605	91	22	0.1%pbs	0.1%pbs	PROPN
bjp-81605	91	23	-	-	PUNCT
bjp-81605	91	24	t	t	PROPN
bjp-81605	91	25	was	be	AUX
bjp-81605	91	26	added	add	VERB
bjp-81605	91	27	after	after	ADP
bjp-81605	91	28	two	two	NUM
bjp-81605	91	29	pbs	pbs	PROPN
bjp-81605	91	30	-	-	PUNCT
bjp-81605	91	31	twin	twin	ADJ
bjp-81605	91	32	washes	wash	NOUN
bjp-81605	91	33	,	,	PUNCT
bjp-81605	91	34	and	and	CCONJ
bjp-81605	91	35	it	it	PRON
bjp-81605	91	36	was	be	AUX
bjp-81605	91	37	left	leave	VERB
bjp-81605	91	38	for	for	ADP
bjp-81605	91	39	an	an	DET
bjp-81605	91	40	hour	hour	NOUN
bjp-81605	91	41	.	.	PUNCT
bjp-81605	92	1	step	step	NOUN
bjp-81605	92	2	7	7	NUM
bjp-81605	92	3	:	:	PUNCT
bjp-81605	92	4	the	the	DET
bjp-81605	92	5	cells	cell	NOUN
bjp-81605	92	6	were	be	AUX
bjp-81605	92	7	then	then	ADV
bjp-81605	92	8	treated	treat	VERB
bjp-81605	92	9	overnight	overnight	ADV
bjp-81605	92	10	at	at	ADP
bjp-81605	92	11	4	4	NUM
bjp-81605	92	12	°	°	ADP
bjp-81605	92	13	c	c	NOUN
bjp-81605	92	14	with	with	ADP
bjp-81605	92	15	a	a	DET
bjp-81605	92	16	primary	primary	ADJ
bjp-81605	92	17	antibody	antibody	NOUN
bjp-81605	92	18	against	against	ADP
bjp-81605	92	19	vegfr1	vegfr1	NOUN
bjp-81605	92	20	.	.	PUNCT
bjp-81605	93	1	step	step	NOUN
bjp-81605	93	2	8	8	NUM
bjp-81605	93	3	:	:	PUNCT
bjp-81605	93	4	after	after	ADP
bjp-81605	93	5	four	four	NUM
bjp-81605	93	6	washes	wash	NOUN
bjp-81605	93	7	,	,	PUNCT
bjp-81605	93	8	the	the	DET
bjp-81605	93	9	anti	anti	ADJ
bjp-81605	93	10	-	-	ADJ
bjp-81605	93	11	mouse	mouse	ADJ
bjp-81605	93	12	igg	igg	PROPN
bjp-81605	93	13	secondary	secondary	ADJ
bjp-81605	93	14	antibody	antibody	NOUN
bjp-81605	93	15	was	be	AUX
bjp-81605	93	16	phycoerythrin	phycoerythrin	NOUN
bjp-81605	93	17	-	-	PUNCT
bjp-81605	93	18	labeled	label	VERB
bjp-81605	93	19	and	and	CCONJ
bjp-81605	93	20	then	then	ADV
bjp-81605	93	21	placed	place	VERB
bjp-81605	93	22	into	into	ADP
bjp-81605	93	23	action	action	NOUN
bjp-81605	93	24	.	.	PUNCT
bjp-81605	94	1	step	step	NOUN
bjp-81605	94	2	9	9	NUM
bjp-81605	94	3	:	:	PUNCT
bjp-81605	94	4	counterstained	counterstaine	VERB
bjp-81605	94	5	cells	cell	NOUN
bjp-81605	94	6	were	be	AUX
bjp-81605	94	7	examined	examine	VERB
bjp-81605	94	8	under	under	ADP
bjp-81605	94	9	a	a	DET
bjp-81605	94	10	microscope	microscope	NOUN
bjp-81605	94	11	with	with	ADP
bjp-81605	94	12	a	a	DET
bjp-81605	94	13	fluorescent	fluorescent	ADJ
bjp-81605	94	14	field	field	NOUN
bjp-81605	94	15	.	.	PUNCT
bjp-81605	95	1	reference	reference	NOUN
bjp-81605	95	2	ara	ara	PROPN
bjp-81605	95	3	et	et	PROPN
bjp-81605	95	4	al	al	PROPN
bjp-81605	95	5	.	.	PROPN
bjp-81605	95	6	,	,	PUNCT
bjp-81605	95	7	2012	2012	NUM
bjp-81605	95	8	bangladesh	bangladesh	PROPN
bjp-81605	95	9	j	j	PROPN
bjp-81605	95	10	pharmacol	pharmacol	PROPN
bjp-81605	95	11	2025	2025	NUM
bjp-81605	95	12	;	;	PUNCT
bjp-81605	95	13	20	20	NUM
bjp-81605	95	14	:	:	SYM
bjp-81605	95	15	89	89	NUM
bjp-81605	95	16	-	-	SYM
bjp-81605	95	17	100	100	NUM
bjp-81605	95	18	91	91	NUM
bjp-81605	95	19	concentration	concentration	NOUN
bjp-81605	95	20	was	be	AUX
bjp-81605	95	21	measured	measure	VERB
bjp-81605	95	22	using	use	VERB
bjp-81605	95	23	the	the	DET
bjp-81605	95	24	bradford	bradford	PROPN
bjp-81605	95	25	method	method	NOUN
bjp-81605	95	26	,	,	PUNCT
bjp-81605	95	27	nanodrop	nanodrop	NOUN
bjp-81605	95	28	(	(	PUNCT
bjp-81605	95	29	molecular	molecular	ADJ
bjp-81605	95	30	devices	device	NOUN
bjp-81605	95	31	,	,	PUNCT
bjp-81605	95	32	usa	usa	PROPN
bjp-81605	95	33	)	)	PUNCT
bjp-81605	95	34	.	.	PUNCT
bjp-81605	96	1	in	in	ADP
bjp-81605	96	2	each	each	DET
bjp-81605	96	3	sample	sample	NOUN
bjp-81605	96	4	,	,	PUNCT
bjp-81605	96	5	20	20	NUM
bjp-81605	96	6	µg	µg	NOUN
bjp-81605	96	7	of	of	ADP
bjp-81605	96	8	total	total	ADJ
bjp-81605	96	9	protein	protein	NOUN
bjp-81605	96	10	was	be	AUX
bjp-81605	96	11	used	use	VERB
bjp-81605	96	12	for	for	ADP
bjp-81605	96	13	sds	sds	NOUN
bjp-81605	96	14	-	-	PUNCT
bjp-81605	96	15	page	page	NOUN
bjp-81605	96	16	gel	gel	NOUN
bjp-81605	96	17	running	running	NOUN
bjp-81605	96	18	.	.	PUNCT
bjp-81605	97	1	after	after	ADP
bjp-81605	97	2	being	be	AUX
bjp-81605	97	3	placed	place	VERB
bjp-81605	97	4	into	into	ADP
bjp-81605	97	5	a	a	DET
bjp-81605	97	6	nitrocellulose	nitrocellulose	NOUN
bjp-81605	97	7	membrane	membrane	NOUN
bjp-81605	97	8	,	,	PUNCT
bjp-81605	97	9	proteins	protein	NOUN
bjp-81605	97	10	were	be	AUX
bjp-81605	97	11	blocked	block	VERB
bjp-81605	97	12	with	with	ADP
bjp-81605	97	13	3	3	NUM
bjp-81605	97	14	%	%	NOUN
bjp-81605	97	15	bovine	bovine	NOUN
bjp-81605	97	16	serum	serum	NOUN
bjp-81605	97	17	albumin	albumin	PROPN
bjp-81605	97	18	(	(	PUNCT
bjp-81605	97	19	bsa	bsa	PROPN
bjp-81605	97	20	)	)	PUNCT
bjp-81605	97	21	in	in	ADP
bjp-81605	97	22	tbst	tbst	ADJ
bjp-81605	97	23	buffer	buffer	NOUN
bjp-81605	97	24	for	for	ADP
bjp-81605	97	25	90	90	NUM
bjp-81605	97	26	min	min	NOUN
bjp-81605	97	27	.	.	PROPN
bjp-81605	97	28	primary	primary	ADJ
bjp-81605	97	29	antibodies	antibody	NOUN
bjp-81605	97	30	against	against	ADP
bjp-81605	97	31	bax	bax	PROPN
bjp-81605	97	32	(	(	PUNCT
bjp-81605	97	33	1:1000	1:1000	NUM
bjp-81605	97	34	)	)	PUNCT
bjp-81605	97	35	,	,	PUNCT
bjp-81605	97	36	bcl-2	bcl-2	PUNCT
bjp-81605	97	37	(	(	PUNCT
bjp-81605	97	38	1:1000	1:1000	NUM
bjp-81605	97	39	)	)	PUNCT
bjp-81605	97	40	,	,	PUNCT
bjp-81605	97	41	p	p	X
bjp-81605	97	42	-	-	PUNCT
bjp-81605	97	43	erk1	erk1	PROPN
bjp-81605	97	44	(	(	PUNCT
bjp-81605	97	45	1:1000	1:1000	NUM
bjp-81605	97	46	)	)	PUNCT
bjp-81605	97	47	,	,	PUNCT
bjp-81605	97	48	p	p	PROPN
bjp-81605	97	49	-	-	PUNCT
bjp-81605	97	50	akt	akt	NOUN
bjp-81605	97	51	(	(	PUNCT
bjp-81605	97	52	1:1000	1:1000	NUM
bjp-81605	97	53	)	)	PUNCT
bjp-81605	97	54	,	,	PUNCT
bjp-81605	97	55	and	and	CCONJ
bjp-81605	97	56	vegf-1	vegf-1	PROPN
bjp-81605	97	57	(	(	PUNCT
bjp-81605	97	58	1:1000	1:1000	NUM
bjp-81605	97	59	)	)	PUNCT
bjp-81605	97	60	were	be	AUX
bjp-81605	97	61	incubated	incubate	VERB
bjp-81605	97	62	with	with	ADP
bjp-81605	97	63	blocked	block	VERB
bjp-81605	97	64	membranes	membrane	NOUN
bjp-81605	97	65	and	and	CCONJ
bjp-81605	97	66	β	β	NOUN
bjp-81605	97	67	-	-	NOUN
bjp-81605	97	68	actin	actin	NOUN
bjp-81605	97	69	(	(	PUNCT
bjp-81605	97	70	1:000	1:000	NUM
bjp-81605	97	71	)	)	PUNCT
bjp-81605	97	72	.	.	PUNCT
bjp-81605	98	1	the	the	DET
bjp-81605	98	2	reference	reference	NOUN
bjp-81605	98	3	protein	protein	NOUN
bjp-81605	98	4	was	be	AUX
bjp-81605	98	5	incubated	incubate	VERB
bjp-81605	98	6	overnight	overnight	ADV
bjp-81605	98	7	at	at	ADP
bjp-81605	98	8	4	4	NUM
bjp-81605	98	9	°	°	NOUN
bjp-81605	98	10	c	c	NOUN
bjp-81605	98	11	.	.	PUNCT
bjp-81605	99	1	on	on	ADP
bjp-81605	99	2	day	day	NOUN
bjp-81605	99	3	two	two	NUM
bjp-81605	99	4	,	,	PUNCT
bjp-81605	99	5	the	the	DET
bjp-81605	99	6	membrane	membrane	NOUN
bjp-81605	99	7	was	be	AUX
bjp-81605	99	8	rinsed	rinse	VERB
bjp-81605	99	9	three	three	NUM
bjp-81605	99	10	times	time	NOUN
bjp-81605	99	11	at	at	ADP
bjp-81605	99	12	10	10	NUM
bjp-81605	99	13	-	-	PUNCT
bjp-81605	99	14	min	min	NOUN
bjp-81605	99	15	intervals	interval	NOUN
bjp-81605	99	16	using	use	VERB
bjp-81605	99	17	tbst	tbst	ADJ
bjp-81605	99	18	washing	washing	NOUN
bjp-81605	99	19	buffer	buffer	NOUN
bjp-81605	99	20	.	.	PUNCT
bjp-81605	100	1	subsequently	subsequently	ADV
bjp-81605	100	2	,	,	PUNCT
bjp-81605	100	3	the	the	DET
bjp-81605	100	4	membrane	membrane	NOUN
bjp-81605	100	5	was	be	AUX
bjp-81605	100	6	treated	treat	VERB
bjp-81605	100	7	with	with	ADP
bjp-81605	100	8	goat	goat	PROPN
bjp-81605	100	9	anti	anti	PROPN
bjp-81605	100	10	-rabbit	-rabbit	PROPN
bjp-81605	100	11	conjugated	conjugated	ADJ
bjp-81605	100	12	igg	igg	PROPN
bjp-81605	100	13	-	-	PUNCT
bjp-81605	100	14	hrp	hrp	PROPN
bjp-81605	100	15	(	(	PUNCT
bjp-81605	100	16	1:2000	1:2000	NUM
bjp-81605	100	17	)	)	PUNCT
bjp-81605	100	18	as	as	ADP
bjp-81605	100	19	the	the	DET
bjp-81605	100	20	secondary	secondary	ADJ
bjp-81605	100	21	antibody	antibody	NOUN
bjp-81605	100	22	for	for	ADP
bjp-81605	100	23	three	three	NUM
bjp-81605	100	24	hours	hour	NOUN
bjp-81605	100	25	at	at	ADP
bjp-81605	100	26	room	room	NOUN
bjp-81605	100	27	temperature	temperature	NOUN
bjp-81605	100	28	.	.	PUNCT
bjp-81605	101	1	the	the	DET
bjp-81605	101	2	blot	blot	NOUN
bjp-81605	101	3	was	be	AUX
bjp-81605	101	4	rinsed	rinse	VERB
bjp-81605	101	5	three	three	NUM
bjp-81605	101	6	times	time	NOUN
bjp-81605	101	7	with	with	ADP
bjp-81605	101	8	tbst	tbst	NOUN
bjp-81605	101	9	after	after	ADP
bjp-81605	101	10	incubating	incubate	VERB
bjp-81605	101	11	with	with	ADP
bjp-81605	101	12	the	the	DET
bjp-81605	101	13	secondary	secondary	ADJ
bjp-81605	101	14	antibody	antibody	NOUN
bjp-81605	101	15	,	,	PUNCT
bjp-81605	101	16	with	with	ADP
bjp-81605	101	17	a	a	DET
bjp-81605	101	18	10	10	NUM
bjp-81605	101	19	-	-	PUNCT
bjp-81605	101	20	min	min	NOUN
bjp-81605	101	21	break	break	NOUN
bjp-81605	101	22	between	between	ADP
bjp-81605	101	23	each	each	DET
bjp-81605	101	24	wash	wash	NOUN
bjp-81605	101	25	.	.	PUNCT
bjp-81605	102	1	after	after	ADP
bjp-81605	102	2	washing	wash	VERB
bjp-81605	102	3	with	with	ADP
bjp-81605	102	4	tbs	tbs	NOUN
bjp-81605	102	5	-	-	PUNCT
bjp-81605	102	6	t	t	NOUN
bjp-81605	102	7	,	,	PUNCT
bjp-81605	102	8	the	the	DET
bjp-81605	102	9	membrane	membrane	NOUN
bjp-81605	102	10	was	be	AUX
bjp-81605	102	11	coated	coat	VERB
bjp-81605	102	12	with	with	ADP
bjp-81605	102	13	1	1	NUM
bjp-81605	102	14	ml	ml	NOUN
bjp-81605	102	15	of	of	ADP
bjp-81605	102	16	pierce	pierce	PROPN
bjp-81605	102	17	ecl	ecl	PROPN
bjp-81605	102	18	western	western	ADJ
bjp-81605	102	19	blot	blot	NOUN
bjp-81605	102	20	substrate	substrate	NOUN
bjp-81605	102	21	(	(	PUNCT
bjp-81605	102	22	cat	cat	NOUN
bjp-81605	102	23	no	no	NOUN
bjp-81605	102	24	.	.	PROPN
bjp-81605	102	25	32106	32106	NUM
bjp-81605	102	26	)	)	PUNCT
bjp-81605	102	27	.	.	PUNCT
bjp-81605	103	1	the	the	DET
bjp-81605	103	2	gel	gel	NOUN
bjp-81605	103	3	dock	dock	NOUN
bjp-81605	103	4	system	system	NOUN
bjp-81605	103	5	,	,	PUNCT
bjp-81605	103	6	g	g	NOUN
bjp-81605	103	7	:	:	PUNCT
bjp-81605	103	8	box	box	PROPN
bjp-81605	103	9	(	(	PUNCT
bjp-81605	103	10	syngene	syngene	PROPN
bjp-81605	103	11	,	,	PUNCT
bjp-81605	103	12	usa	usa	PROPN
bjp-81605	103	13	)	)	PUNCT
bjp-81605	103	14	,	,	PUNCT
bjp-81605	103	15	was	be	AUX
bjp-81605	103	16	then	then	ADV
bjp-81605	103	17	used	use	VERB
bjp-81605	103	18	to	to	PART
bjp-81605	103	19	identify	identify	VERB
bjp-81605	103	20	the	the	DET
bjp-81605	103	21	protein	protein	NOUN
bjp-81605	103	22	bands	band	NOUN
bjp-81605	103	23	on	on	ADP
bjp-81605	103	24	the	the	DET
bjp-81605	103	25	membrane	membrane	NOUN
bjp-81605	103	26	.	.	PUNCT
bjp-81605	104	1	statistical	statistical	ADJ
bjp-81605	104	2	analysis	analysis	NOUN
bjp-81605	104	3	data	datum	NOUN
bjp-81605	104	4	were	be	AUX
bjp-81605	104	5	expressed	express	VERB
bjp-81605	104	6	as	as	ADP
bjp-81605	104	7	mean	mean	PROPN
bjp-81605	104	8	±	±	NUM
bjp-81605	104	9	sem	sem	NOUN
bjp-81605	104	10	.	.	PUNCT
bjp-81605	105	1	the	the	DET
bjp-81605	105	2	results	result	NOUN
bjp-81605	105	3	were	be	AUX
bjp-81605	105	4	subjected	subject	VERB
bjp-81605	105	5	to	to	ADP
bjp-81605	105	6	one	one	NUM
bjp-81605	105	7	-	-	PUNCT
bjp-81605	105	8	way	way	NOUN
bjp-81605	105	9	anova	anova	PROPN
bjp-81605	105	10	to	to	PART
bjp-81605	105	11	analyze	analyze	VERB
bjp-81605	105	12	the	the	DET
bjp-81605	105	13	differences	difference	NOUN
bjp-81605	105	14	between	between	ADP
bjp-81605	105	15	the	the	DET
bjp-81605	105	16	treatment	treatment	NOUN
bjp-81605	105	17	groups	group	NOUN
bjp-81605	105	18	and	and	CCONJ
bjp-81605	105	19	the	the	DET
bjp-81605	105	20	control	control	NOUN
bjp-81605	105	21	groups	group	NOUN
bjp-81605	105	22	.	.	PUNCT
bjp-81605	106	1	a	a	DET
bjp-81605	106	2	p	p	NOUN
bjp-81605	106	3	-	-	PUNCT
bjp-81605	106	4	value	value	NOUN
bjp-81605	106	5	of	of	ADP
bjp-81605	106	6	<	<	NOUN
bjp-81605	106	7	0.05	0.05	NUM
bjp-81605	106	8	was	be	AUX
bjp-81605	106	9	considered	consider	VERB
bjp-81605	106	10	significant	significant	ADJ
bjp-81605	106	11	.	.	PUNCT
bjp-81605	107	1	results	result	VERB
bjp-81605	107	2	molecular	molecular	ADJ
bjp-81605	107	3	interaction	interaction	NOUN
bjp-81605	107	4	predictions	prediction	NOUN
bjp-81605	107	5	with	with	ADP
bjp-81605	107	6	vegf	vegf	NOUN
bjp-81605	107	7	-	-	PUNCT
bjp-81605	107	8	a/	a/	PROPN
bjp-81605	107	9	vegfr1	vegfr1	NOUN
bjp-81605	107	10	binding	bind	VERB
bjp-81605	107	11	pocket	pocket	NOUN
bjp-81605	107	12	the	the	DET
bjp-81605	107	13	results	result	NOUN
bjp-81605	107	14	suggested	suggest	VERB
bjp-81605	107	15	that	that	SCONJ
bjp-81605	107	16	molecular	molecular	ADJ
bjp-81605	107	17	modeling	modeling	NOUN
bjp-81605	107	18	of	of	ADP
bjp-81605	107	19	crt2	crt2	PROPN
bjp-81605	107	20	and	and	CCONJ
bjp-81605	107	21	vegfr1	vegfr1	NOUN
bjp-81605	107	22	had	have	VERB
bjp-81605	107	23	a	a	DET
bjp-81605	107	24	more	more	ADV
bjp-81605	107	25	promising	promising	ADJ
bjp-81605	107	26	relationship	relationship	NOUN
bjp-81605	107	27	.	.	PUNCT
bjp-81605	108	1	nonetheless	nonetheless	ADV
bjp-81605	108	2	,	,	PUNCT
bjp-81605	108	3	for	for	ADP
bjp-81605	108	4	the	the	DET
bjp-81605	108	5	binding	binding	NOUN
bjp-81605	108	6	of	of	ADP
bjp-81605	108	7	vegfr1	vegfr1	NOUN
bjp-81605	108	8	with	with	ADP
bjp-81605	108	9	ctr2	ctr2	PROPN
bjp-81605	108	10	peptide	peptide	NOUN
bjp-81605	108	11	,	,	PUNCT
bjp-81605	108	12	the	the	DET
bjp-81605	108	13	highest	highest	ADV
bjp-81605	108	14	-	-	PUNCT
bjp-81605	108	15	scored	score	VERB
bjp-81605	108	16	superimposed	superimpose	VERB
bjp-81605	108	17	structures	structure	NOUN
bjp-81605	108	18	were	be	AUX
bjp-81605	108	19	employed	employ	VERB
bjp-81605	108	20	.	.	PUNCT
bjp-81605	109	1	the	the	DET
bjp-81605	109	2	pdb	pdb	PROPN
bjp-81605	109	3	databank	databank	PROPN
bjp-81605	109	4	(	(	PUNCT
bjp-81605	109	5	2xac	2xac	PROPN
bjp-81605	109	6	)	)	PUNCT
bjp-81605	109	7	provided	provide	VERB
bjp-81605	109	8	the	the	DET
bjp-81605	109	9	protein	protein	NOUN
bjp-81605	109	10	structures	structure	NOUN
bjp-81605	109	11	of	of	ADP
bjp-81605	109	12	vegfr1	vegfr1	NOUN
bjp-81605	109	13	and	and	CCONJ
bjp-81605	109	14	the	the	DET
bjp-81605	109	15	co	co	NOUN
bjp-81605	109	16	-	-	NOUN
bjp-81605	109	17	crystal	crystal	ADJ
bjp-81605	109	18	ligand	ligand	ADJ
bjp-81605	109	19	molecule	molecule	NOUN
bjp-81605	109	20	shown	show	VERB
bjp-81605	109	21	in	in	ADP
bjp-81605	109	22	figure	figure	NOUN
bjp-81605	109	23	1a	1a	PROPN
bjp-81605	109	24	-	-	PUNCT
bjp-81605	109	25	b.	b.	PROPN
bjp-81605	109	26	it	it	PRON
bjp-81605	109	27	was	be	AUX
bjp-81605	109	28	determined	determine	VERB
bjp-81605	109	29	that	that	SCONJ
bjp-81605	109	30	the	the	DET
bjp-81605	109	31	binding	bind	VERB
bjp-81605	109	32	energy	energy	NOUN
bjp-81605	109	33	between	between	ADP
bjp-81605	109	34	crt2	crt2	PROPN
bjp-81605	109	35	and	and	CCONJ
bjp-81605	109	36	vegfr1	vegfr1	NOUN
bjp-81605	109	37	is	be	AUX
bjp-81605	109	38	37.05	37.05	NUM
bjp-81605	109	39	kcal	kcal	PROPN
bjp-81605	109	40	/	/	SYM
bjp-81605	109	41	mol	mol	PROPN
bjp-81605	109	42	,	,	PUNCT
bjp-81605	109	43	demonstrating	demonstrate	VERB
bjp-81605	109	44	that	that	SCONJ
bjp-81605	109	45	crt2	crt2	PROPN
bjp-81605	109	46	can	can	AUX
bjp-81605	109	47	bind	bind	VERB
bjp-81605	109	48	to	to	ADP
bjp-81605	109	49	the	the	DET
bjp-81605	109	50	vegfr1	vegfr1	NOUN
bjp-81605	109	51	receptor	receptor	NOUN
bjp-81605	109	52	.	.	PUNCT
bjp-81605	110	1	moreover	moreover	ADV
bjp-81605	110	2	,	,	PUNCT
bjp-81605	110	3	a	a	DET
bjp-81605	110	4	thorough	thorough	ADJ
bjp-81605	110	5	examination	examination	NOUN
bjp-81605	110	6	of	of	ADP
bjp-81605	110	7	ligand	ligand	ADJ
bjp-81605	110	8	-	-	PUNCT
bjp-81605	110	9	protein	protein	NOUN
bjp-81605	110	10	interactions	interaction	NOUN
bjp-81605	110	11	using	use	VERB
bjp-81605	110	12	pymol	pymol	PROPN
bjp-81605	110	13	and	and	CCONJ
bjp-81605	110	14	ligplot+	ligplot+	PROPN
bjp-81605	110	15	revealed	reveal	VERB
bjp-81605	110	16	that	that	SCONJ
bjp-81605	110	17	crt2	crt2	PROPN
bjp-81605	110	18	interacts	interact	VERB
bjp-81605	110	19	with	with	ADP
bjp-81605	110	20	vegf	vegf	NOUN
bjp-81605	110	21	-	-	PUNCT
bjp-81605	110	22	b/	b/	NOUN
bjp-81605	110	23	vegfr1	vegfr1	NOUN
bjp-81605	110	24	residues	residue	NOUN
bjp-81605	110	25	,	,	PUNCT
bjp-81605	110	26	including	include	VERB
bjp-81605	110	27	glu59	glu59	PROPN
bjp-81605	110	28	,	,	PUNCT
bjp-81605	110	29	his145	his145	PROPN
bjp-81605	110	30	,	,	PUNCT
bjp-81605	110	31	gln146	gln146	PROPN
bjp-81605	110	32	,	,	PUNCT
bjp-81605	110	33	ser186	ser186	PROPN
bjp-81605	110	34	,	,	PUNCT
bjp-81605	110	35	trp226	trp226	NOUN
bjp-81605	110	36	,	,	PUNCT
bjp-81605	110	37	arg225	arg225	PROPN
bjp-81605	110	38	,	,	PUNCT
bjp-81605	110	39	and	and	CCONJ
bjp-81605	110	40	lys265	lys265	VERB
bjp-81605	110	41	through	through	ADP
bjp-81605	110	42	hydrophobic	hydrophobic	NOUN
bjp-81605	110	43	and	and	CCONJ
bjp-81605	110	44	van	van	PROPN
bjp-81605	110	45	der	der	NOUN
bjp-81605	110	46	waals	waal	NOUN
bjp-81605	110	47	contacts	contact	NOUN
bjp-81605	110	48	(	(	PUNCT
bjp-81605	110	49	figure	figure	NOUN
bjp-81605	110	50	1b	1b	NUM
bjp-81605	110	51	)	)	PUNCT
bjp-81605	110	52	.	.	PUNCT
bjp-81605	111	1	the	the	DET
bjp-81605	111	2	most	most	ADV
bjp-81605	111	3	hydrophobic	hydrophobic	NOUN
bjp-81605	111	4	peptide	peptide	NOUN
bjp-81605	111	5	amino	amino	NOUN
bjp-81605	111	6	acid	acid	NOUN
bjp-81605	111	7	residues	residue	NOUN
bjp-81605	111	8	of	of	ADP
bjp-81605	111	9	crt2	crt2	NOUN
bjp-81605	111	10	are	be	AUX
bjp-81605	111	11	found	find	VERB
bjp-81605	111	12	in	in	ADP
bjp-81605	111	13	the	the	DET
bjp-81605	111	14	van	van	PROPN
bjp-81605	111	15	der	der	NOUN
bjp-81605	111	16	waals	waal	NOUN
bjp-81605	111	17	interaction	interaction	NOUN
bjp-81605	111	18	,	,	PUNCT
bjp-81605	111	19	specifically	specifically	ADV
bjp-81605	111	20	arg4	arg4	NOUN
bjp-81605	111	21	,	,	PUNCT
bjp-81605	111	22	ser9	ser9	ADJ
bjp-81605	111	23	,	,	PUNCT
bjp-81605	111	24	tyr10	tyr10	NOUN
bjp-81605	111	25	,	,	PUNCT
bjp-81605	111	26	and	and	CCONJ
bjp-81605	111	27	met19	met19	PROPN
bjp-81605	111	28	.	.	PUNCT
bjp-81605	112	1	the	the	DET
bjp-81605	112	2	present	present	ADJ
bjp-81605	112	3	derivative	derivative	ADJ
bjp-81605	112	4	crt2	crt2	PROPN
bjp-81605	112	5	:	:	PUNCT
bjp-81605	112	6	vegfr1	vegfr1	NOUN
bjp-81605	112	7	with	with	ADP
bjp-81605	112	8	all	all	PRON
bjp-81605	112	9	interacting	interact	VERB
bjp-81605	112	10	active	active	ADJ
bjp-81605	112	11	residues	residue	NOUN
bjp-81605	112	12	and	and	CCONJ
bjp-81605	112	13	the	the	DET
bjp-81605	112	14	full	full	ADJ
bjp-81605	112	15	crystal	crystal	NOUN
bjp-81605	112	16	structure	structure	NOUN
bjp-81605	112	17	of	of	ADP
bjp-81605	112	18	vegfb	vegfb	NOUN
bjp-81605	112	19	:	:	PUNCT
bjp-81605	112	20	vegfr1	vegfr1	NOUN
bjp-81605	112	21	(	(	PUNCT
bjp-81605	112	22	pdb	pdb	PROPN
bjp-81605	112	23	i	i	PROPN
bjp-81605	112	24	d	d	PROPN
bjp-81605	112	25	:	:	PUNCT
bjp-81605	112	26	2xac	2xac	NUM
bjp-81605	112	27	)	)	PUNCT
bjp-81605	112	28	are	be	AUX
bjp-81605	112	29	briefly	briefly	ADV
bjp-81605	112	30	compared	compare	VERB
bjp-81605	112	31	according	accord	VERB
bjp-81605	112	32	to	to	ADP
bjp-81605	112	33	the	the	DET
bjp-81605	112	34	vegfr1	vegfr1	NOUN
bjp-81605	112	35	ribbon	ribbon	NOUN
bjp-81605	112	36	and	and	CCONJ
bjp-81605	112	37	surface	surface	NOUN
bjp-81605	112	38	filling	fill	VERB
bjp-81605	112	39	model	model	NOUN
bjp-81605	112	40	.	.	PUNCT
bjp-81605	113	1	crt2	crt2	PROPN
bjp-81605	113	2	(	(	PUNCT
bjp-81605	113	3	stick	stick	NOUN
bjp-81605	113	4	shape	shape	NOUN
bjp-81605	113	5	)	)	PUNCT
bjp-81605	113	6	firmly	firmly	ADV
bjp-81605	113	7	fits	fit	VERB
bjp-81605	113	8	into	into	ADP
bjp-81605	113	9	the	the	DET
bjp-81605	113	10	kinase	kinase	NOUN
bjp-81605	113	11	pocket	pocket	NOUN
bjp-81605	113	12	(	(	PUNCT
bjp-81605	113	13	figure	figure	NOUN
bjp-81605	113	14	1c	1c	NOUN
bjp-81605	113	15	)	)	PUNCT
bjp-81605	113	16	.	.	PUNCT
bjp-81605	114	1	molecular	molecular	ADJ
bjp-81605	114	2	dynamic	dynamic	ADJ
bjp-81605	114	3	modeling	modeling	NOUN
bjp-81605	114	4	of	of	ADP
bjp-81605	114	5	crt2	crt2	PROPN
bjp-81605	114	6	/	/	SYM
bjp-81605	114	7	vegfr1	vegfr1	NOUN
bjp-81605	114	8	interaction	interaction	NOUN
bjp-81605	114	9	under	under	ADP
bjp-81605	114	10	physiological	physiological	ADJ
bjp-81605	114	11	conditions	condition	NOUN
bjp-81605	114	12	under	under	ADP
bjp-81605	114	13	physiological	physiological	ADJ
bjp-81605	114	14	conditions	condition	NOUN
bjp-81605	114	15	,	,	PUNCT
bjp-81605	114	16	the	the	DET
bjp-81605	114	17	stability	stability	NOUN
bjp-81605	114	18	of	of	ADP
bjp-81605	114	19	the	the	DET
bjp-81605	114	20	vegfr1	vegfr1	NOUN
bjp-81605	114	21	-	-	PUNCT
bjp-81605	114	22	crt2	crt2	PROPN
bjp-81605	114	23	interactions	interaction	NOUN
bjp-81605	114	24	had	have	AUX
bjp-81605	114	25	been	be	AUX
bjp-81605	114	26	validated	validate	VERB
bjp-81605	114	27	by	by	ADP
bjp-81605	114	28	molecular	molecular	ADJ
bjp-81605	114	29	dynamics	dynamic	NOUN
bjp-81605	114	30	simulation	simulation	NOUN
bjp-81605	114	31	and	and	CCONJ
bjp-81605	114	32	docking	docking	NOUN
bjp-81605	114	33	experiments	experiment	NOUN
bjp-81605	114	34	.	.	PUNCT
bjp-81605	115	1	according	accord	VERB
bjp-81605	115	2	to	to	ADP
bjp-81605	115	3	hydrogen	hydrogen	NOUN
bjp-81605	115	4	bond	bond	NOUN
bjp-81605	115	5	studies	study	NOUN
bjp-81605	115	6	,	,	PUNCT
bjp-81605	115	7	crt2	crt2	PROPN
bjp-81605	115	8	was	be	AUX
bjp-81605	115	9	mostly	mostly	ADV
bjp-81605	115	10	supported	support	VERB
bjp-81605	115	11	by	by	ADP
bjp-81605	115	12	polar	polar	ADJ
bjp-81605	115	13	contacts	contact	NOUN
bjp-81605	115	14	with	with	ADP
bjp-81605	115	15	water	water	NOUN
bjp-81605	115	16	molecules	molecule	NOUN
bjp-81605	115	17	and	and	CCONJ
bjp-81605	115	18	forms	form	VERB
bjp-81605	115	19	hydrogen	hydrogen	NOUN
bjp-81605	115	20	bonds	bond	NOUN
bjp-81605	115	21	principally	principally	ADV
bjp-81605	115	22	with	with	ADP
bjp-81605	115	23	glu59	glu59	PROPN
bjp-81605	115	24	,	,	PUNCT
bjp-81605	115	25	with	with	ADP
bjp-81605	115	26	a	a	DET
bjp-81605	115	27	high	high	ADJ
bjp-81605	115	28	occupancy	occupancy	NOUN
bjp-81605	115	29	value	value	NOUN
bjp-81605	115	30	.	.	PUNCT
bjp-81605	116	1	the	the	DET
bjp-81605	116	2	molecular	molecular	ADJ
bjp-81605	116	3	docking	docking	NOUN
bjp-81605	116	4	,	,	PUNCT
bjp-81605	116	5	crt2	crt2	PROPN
bjp-81605	116	6	,	,	PUNCT
bjp-81605	116	7	was	be	AUX
bjp-81605	116	8	able	able	ADJ
bjp-81605	116	9	to	to	PART
bjp-81605	116	10	fit	fit	VERB
bjp-81605	116	11	into	into	ADP
bjp-81605	116	12	the	the	DET
bjp-81605	116	13	vegfr1	vegfr1	NOUN
bjp-81605	116	14	kinase	kinase	PROPN
bjp-81605	116	15	domain	domain	NOUN
bjp-81605	116	16	pocket	pocket	NOUN
bjp-81605	116	17	with	with	ADP
bjp-81605	116	18	the	the	DET
bjp-81605	116	19	assistance	assistance	NOUN
bjp-81605	116	20	of	of	ADP
bjp-81605	116	21	seven	seven	NUM
bjp-81605	116	22	front	front	NOUN
bjp-81605	116	23	and	and	CCONJ
bjp-81605	116	24	five	five	NUM
bjp-81605	116	25	rear	rear	ADJ
bjp-81605	116	26	water	water	NOUN
bjp-81605	116	27	molecules	molecule	NOUN
bjp-81605	116	28	(	(	PUNCT
bjp-81605	116	29	figure	figure	NOUN
bjp-81605	116	30	2a	2a	NUM
bjp-81605	116	31	(	(	PUNCT
bjp-81605	116	32	i	i	PRON
bjp-81605	116	33	and	and	CCONJ
bjp-81605	116	34	ii	ii	PROPN
bjp-81605	116	35	)	)	PUNCT
bjp-81605	116	36	)	)	PUNCT
bjp-81605	116	37	.	.	PUNCT
bjp-81605	117	1	using	use	VERB
bjp-81605	117	2	all	all	PRON
bjp-81605	117	3	of	of	ADP
bjp-81605	117	4	the	the	DET
bjp-81605	117	5	default	default	NOUN
bjp-81605	117	6	settings	setting	NOUN
bjp-81605	117	7	from	from	ADP
bjp-81605	117	8	amber	amber	PROPN
bjp-81605	117	9	's	's	PART
bjp-81605	117	10	mmpbsa	mmpbsa	NOUN
bjp-81605	117	11	module	module	NOUN
bjp-81605	117	12	,	,	PUNCT
bjp-81605	117	13	the	the	DET
bjp-81605	117	14	binding	bind	VERB
bjp-81605	117	15	free	free	ADJ
bjp-81605	117	16	energies	energy	NOUN
bjp-81605	117	17	of	of	ADP
bjp-81605	117	18	crt2	crt2	PROPN
bjp-81605	117	19	were	be	AUX
bjp-81605	117	20	calculated	calculate	VERB
bjp-81605	117	21	over	over	ADP
bjp-81605	117	22	the	the	DET
bjp-81605	117	23	previous	previous	ADJ
bjp-81605	117	24	2	2	NUM
bjp-81605	117	25	nsec	nsec	ADJ
bjp-81605	117	26	simulation	simulation	NOUN
bjp-81605	117	27	frames	frame	NOUN
bjp-81605	117	28	using	use	VERB
bjp-81605	117	29	the	the	DET
bjp-81605	117	30	molecular	molecular	ADJ
bjp-81605	117	31	mechanics	mechanic	NOUN
bjp-81605	117	32	poisson	poisson	PROPN
bjp-81605	117	33	-	-	PUNCT
bjp-81605	117	34	boltzmann	boltzmann	PROPN
bjp-81605	117	35	surface	surface	NOUN
bjp-81605	117	36	figure	figure	NOUN
bjp-81605	117	37	1	1	NUM
bjp-81605	117	38	:	:	PUNCT
bjp-81605	117	39	the	the	DET
bjp-81605	117	40	vegfr1	vegfr1	NOUN
bjp-81605	117	41	protein	protein	NOUN
bjp-81605	117	42	interacts	interact	VERB
bjp-81605	117	43	structurally	structurally	ADV
bjp-81605	117	44	with	with	ADP
bjp-81605	117	45	crt2	crt2	PROPN
bjp-81605	117	46	.	.	PUNCT
bjp-81605	118	1	vegf	vegf	PROPN
bjp-81605	118	2	-	-	PUNCT
bjp-81605	118	3	a	a	PROPN
bjp-81605	118	4	and	and	CCONJ
bjp-81605	118	5	vegfr1	vegfr1	NOUN
bjp-81605	118	6	interact	interact	NOUN
bjp-81605	118	7	(	(	PUNCT
bjp-81605	118	8	a	a	NOUN
bjp-81605	118	9	)	)	PUNCT
bjp-81605	118	10	.	.	PUNCT
bjp-81605	119	1	the	the	DET
bjp-81605	119	2	vegf	vegf	PROPN
bjp-81605	119	3	-	-	PUNCT
bjp-81605	119	4	a	a	DET
bjp-81605	119	5	dimer	dimer	NOUN
bjp-81605	119	6	's	's	PART
bjp-81605	119	7	complex	complex	ADJ
bjp-81605	119	8	structure	structure	NOUN
bjp-81605	119	9	with	with	ADP
bjp-81605	119	10	vegfr1	vegfr1	NOUN
bjp-81605	119	11	-	-	PUNCT
bjp-81605	119	12	d1	d1	NOUN
bjp-81605	119	13	-	-	PUNCT
bjp-81605	119	14	d6	d6	NOUN
bjp-81605	119	15	(	(	PUNCT
bjp-81605	119	16	b	b	NOUN
bjp-81605	119	17	)	)	PUNCT
bjp-81605	119	18	.	.	PUNCT
bjp-81605	120	1	the	the	DET
bjp-81605	120	2	crt2	crt2	PROPN
bjp-81605	120	3	peptide	peptide	NOUN
bjp-81605	120	4	binds	bind	VERB
bjp-81605	120	5	to	to	ADP
bjp-81605	120	6	an	an	DET
bjp-81605	120	7	overall	overall	ADJ
bjp-81605	120	8	amino	amino	NOUN
bjp-81605	120	9	acid	acid	NOUN
bjp-81605	120	10	in	in	ADP
bjp-81605	120	11	the	the	DET
bjp-81605	120	12	vegfr1	vegfr1	NOUN
bjp-81605	120	13	site	site	NOUN
bjp-81605	120	14	(	(	PUNCT
bjp-81605	120	15	c	c	NOUN
bjp-81605	120	16	)	)	PUNCT
bjp-81605	120	17	.	.	PUNCT
bjp-81605	121	1	pymol	pymol	PROPN
bjp-81605	121	2	and	and	CCONJ
bjp-81605	121	3	ligplot+	ligplot+	PROPN
bjp-81605	121	4	were	be	AUX
bjp-81605	121	5	used	use	VERB
bjp-81605	121	6	to	to	PART
bjp-81605	121	7	visualise	visualise	VERB
bjp-81605	121	8	the	the	DET
bjp-81605	121	9	docking	docking	NOUN
bjp-81605	121	10	complex	complex	NOUN
bjp-81605	121	11	.	.	PUNCT
bjp-81605	122	1	various	various	ADJ
bjp-81605	122	2	ligands	ligand	NOUN
bjp-81605	122	3	that	that	PRON
bjp-81605	122	4	contain	contain	VERB
bjp-81605	122	5	crt2	crt2	PROPN
bjp-81605	122	6	,	,	PUNCT
bjp-81605	122	7	denoted	denote	VERB
bjp-81605	122	8	by	by	ADP
bjp-81605	122	9	green	green	ADJ
bjp-81605	122	10	or	or	CCONJ
bjp-81605	122	11	red	red	ADJ
bjp-81605	122	12	hues	hue	NOUN
bjp-81605	122	13	respectively	respectively	ADV
bjp-81605	122	14	c	c	PROPN
bjp-81605	122	15	b	b	PROPN
bjp-81605	122	16	a	a	DET
bjp-81605	122	17	vegf	vegf	NOUN
bjp-81605	122	18	-	-	PUNCT
bjp-81605	122	19	a	a	DET
bjp-81605	122	20	dimer	dimer	NOUN
bjp-81605	122	21	lys265(a	lys265(a	NOUN
bjp-81605	122	22	)	)	PUNCT
bjp-81605	122	23	arg225(a	arg225(a	NOUN
bjp-81605	122	24	)	)	PUNCT
bjp-81605	122	25	trp226(a	trp226(a	NOUN
bjp-81605	122	26	)	)	PUNCT
bjp-81605	122	27	ser186(a	ser186(a	PROPN
bjp-81605	122	28	)	)	PUNCT
bjp-81605	122	29	gln146(a	gln146(a	NOUN
bjp-81605	122	30	)	)	PUNCT
bjp-81605	122	31	his145(a	his145(a	NOUN
bjp-81605	122	32	)	)	PUNCT
bjp-81605	122	33	glu59(a	glu59(a	NOUN
bjp-81605	122	34	)	)	PUNCT
bjp-81605	122	35	arg4(p	arg4(p	NUM
bjp-81605	122	36	)	)	PUNCT
bjp-81605	122	37	ser9	ser9	ADJ
bjp-81605	122	38	tyr10(p	tyr10(p	ADP
bjp-81605	122	39	)	)	PUNCT
bjp-81605	122	40	tyr13(p	tyr13(p	NUM
bjp-81605	122	41	)	)	PUNCT
bjp-81605	122	42	tyr17(p	tyr17(p	PROPN
bjp-81605	122	43	)	)	PUNCT
bjp-81605	122	44	met19(p	met19(p	NOUN
bjp-81605	122	45	)	)	PUNCT
bjp-81605	122	46	vegf	vegf	NOUN
bjp-81605	122	47	-	-	PUNCT
bjp-81605	122	48	a	a	DET
bjp-81605	122	49	loop	loop	NOUN
bjp-81605	122	50	vegf	vegf	NOUN
bjp-81605	122	51	-	-	PUNCT
bjp-81605	122	52	a	a	DET
bjp-81605	122	53	dimer	dimer	NOUN
bjp-81605	122	54	92	92	NUM
bjp-81605	122	55	bangladesh	bangladesh	NOUN
bjp-81605	122	56	j	j	PROPN
bjp-81605	122	57	pharmacol	pharmacol	PROPN
bjp-81605	122	58	2025	2025	NUM
bjp-81605	122	59	;	;	PUNCT
bjp-81605	122	60	20	20	NUM
bjp-81605	122	61	:	:	SYM
bjp-81605	122	62	89	89	NUM
bjp-81605	122	63	-	-	SYM
bjp-81605	122	64	100	100	NUM
bjp-81605	122	65	area	area	NOUN
bjp-81605	122	66	(	(	PUNCT
bjp-81605	122	67	mmpbsa	mmpbsa	NOUN
bjp-81605	122	68	)	)	PUNCT
bjp-81605	122	69	technique	technique	NOUN
bjp-81605	122	70	(	(	PUNCT
bjp-81605	122	71	figure	figure	NOUN
bjp-81605	122	72	2b	2b	NOUN
bjp-81605	122	73	)	)	PUNCT
bjp-81605	122	74	.	.	PUNCT
bjp-81605	123	1	these	these	DET
bjp-81605	123	2	findings	finding	NOUN
bjp-81605	123	3	imply	imply	VERB
bjp-81605	123	4	that	that	SCONJ
bjp-81605	123	5	the	the	DET
bjp-81605	123	6	electrostatic	electrostatic	ADJ
bjp-81605	123	7	and	and	CCONJ
bjp-81605	123	8	van	van	PROPN
bjp-81605	123	9	der	der	NOUN
bjp-81605	123	10	waals	waal	NOUN
bjp-81605	123	11	interactions	interaction	NOUN
bjp-81605	123	12	contribute	contribute	VERB
bjp-81605	123	13	to	to	ADP
bjp-81605	123	14	the	the	DET
bjp-81605	123	15	energetically	energetically	ADV
bjp-81605	123	16	favorable	favorable	ADJ
bjp-81605	123	17	conformational	conformational	ADJ
bjp-81605	123	18	stability	stability	NOUN
bjp-81605	123	19	of	of	ADP
bjp-81605	123	20	vegfr1	vegfr1	NOUN
bjp-81605	123	21	-	-	PUNCT
bjp-81605	123	22	crt2	crt2	PROPN
bjp-81605	123	23	.	.	PUNCT
bjp-81605	124	1	all	all	DET
bjp-81605	124	2	-	-	PUNCT
bjp-81605	124	3	atom	atom	NOUN
bjp-81605	124	4	molecular	molecular	ADJ
bjp-81605	124	5	dynamics	dynamic	NOUN
bjp-81605	124	6	simulation	simulation	NOUN
bjp-81605	124	7	research	research	NOUN
bjp-81605	124	8	was	be	AUX
bjp-81605	124	9	done	do	VERB
bjp-81605	124	10	on	on	ADP
bjp-81605	124	11	the	the	DET
bjp-81605	124	12	docked	docked	ADJ
bjp-81605	124	13	complex	complex	NOUN
bjp-81605	124	14	to	to	PART
bjp-81605	124	15	obtain	obtain	VERB
bjp-81605	124	16	more	more	ADV
bjp-81605	124	17	mechanistic	mechanistic	ADJ
bjp-81605	124	18	in	in	ADP
bjp-81605	124	19	-	-	PUNCT
bjp-81605	124	20	sights	sight	NOUN
bjp-81605	124	21	into	into	ADP
bjp-81605	124	22	the	the	DET
bjp-81605	124	23	binding	bind	VERB
bjp-81605	124	24	behavior	behavior	NOUN
bjp-81605	124	25	of	of	ADP
bjp-81605	124	26	crt2	crt2	PROPN
bjp-81605	124	27	with	with	ADP
bjp-81605	124	28	vegfr1	vegfr1	NOUN
bjp-81605	124	29	.	.	PUNCT
bjp-81605	125	1	we	we	PRON
bjp-81605	125	2	investigated	investigate	VERB
bjp-81605	125	3	the	the	DET
bjp-81605	125	4	simulated	simulate	VERB
bjp-81605	125	5	trajectory	trajectory	NOUN
bjp-81605	125	6	in	in	ADP
bjp-81605	125	7	more	more	ADJ
bjp-81605	125	8	detail	detail	NOUN
bjp-81605	125	9	.	.	PUNCT
bjp-81605	126	1	the	the	DET
bjp-81605	126	2	system	system	NOUN
bjp-81605	126	3	's	's	PART
bjp-81605	126	4	flexibility	flexibility	NOUN
bjp-81605	126	5	and	and	CCONJ
bjp-81605	126	6	stability	stability	NOUN
bjp-81605	126	7	were	be	AUX
bjp-81605	126	8	ascertained	ascertain	VERB
bjp-81605	126	9	using	use	VERB
bjp-81605	126	10	b	b	NOUN
bjp-81605	126	11	-	-	PUNCT
bjp-81605	126	12	factor	factor	NOUN
bjp-81605	126	13	analysis	analysis	NOUN
bjp-81605	126	14	and	and	CCONJ
bjp-81605	126	15	root	root	NOUN
bjp-81605	126	16	mean	mean	ADJ
bjp-81605	126	17	square	square	ADJ
bjp-81605	126	18	displacement	displacement	NOUN
bjp-81605	126	19	(	(	PUNCT
bjp-81605	126	20	rmsd	rmsd	PROPN
bjp-81605	126	21	)	)	PUNCT
bjp-81605	126	22	,	,	PUNCT
bjp-81605	126	23	as	as	SCONJ
bjp-81605	126	24	illustrated	illustrate	VERB
bjp-81605	126	25	in	in	ADP
bjp-81605	126	26	figure	figure	NOUN
bjp-81605	126	27	2c	2c	NOUN
bjp-81605	126	28	.	.	PUNCT
bjp-81605	127	1	the	the	DET
bjp-81605	127	2	backbone	backbone	NOUN
bjp-81605	127	3	rmsd	rmsd	NOUN
bjp-81605	127	4	of	of	ADP
bjp-81605	127	5	the	the	DET
bjp-81605	127	6	unbound	unbound	ADJ
bjp-81605	127	7	vegfr2	vegfr2	NOUN
bjp-81605	127	8	and	and	CCONJ
bjp-81605	127	9	vegfr2	vegfr2	ADJ
bjp-81605	127	10	-	-	PUNCT
bjp-81605	127	11	andrographolide	andrographolide	ADV
bjp-81605	127	12	complex	complex	NOUN
bjp-81605	127	13	was	be	AUX
bjp-81605	127	14	very	very	ADV
bjp-81605	127	15	low	low	ADJ
bjp-81605	127	16	(	(	PUNCT
bjp-81605	127	17	~1.5–2	~1.5–2	X
bjp-81605	127	18	å	å	NOUN
bjp-81605	127	19	)	)	PUNCT
bjp-81605	127	20	,	,	PUNCT
bjp-81605	127	21	suggesting	suggest	VERB
bjp-81605	127	22	that	that	SCONJ
bjp-81605	127	23	the	the	DET
bjp-81605	127	24	system	system	NOUN
bjp-81605	127	25	remains	remain	VERB
bjp-81605	127	26	stable	stable	ADJ
bjp-81605	127	27	during	during	ADP
bjp-81605	127	28	the	the	DET
bjp-81605	127	29	simulation	simulation	NOUN
bjp-81605	127	30	and	and	CCONJ
bjp-81605	127	31	the	the	DET
bjp-81605	127	32	overall	overall	ADJ
bjp-81605	127	33	structure	structure	NOUN
bjp-81605	127	34	did	do	AUX
bjp-81605	127	35	not	not	PART
bjp-81605	127	36	change	change	VERB
bjp-81605	127	37	signifycantly	signifycantly	ADV
bjp-81605	127	38	from	from	ADP
bjp-81605	127	39	the	the	DET
bjp-81605	127	40	initial	initial	ADJ
bjp-81605	127	41	conformation	conformation	NOUN
bjp-81605	127	42	.	.	PUNCT
bjp-81605	128	1	according	accord	VERB
bjp-81605	128	2	to	to	ADP
bjp-81605	128	3	bfactor	bfactor	NOUN
bjp-81605	128	4	analysis	analysis	NOUN
bjp-81605	128	5	,	,	PUNCT
bjp-81605	128	6	when	when	SCONJ
bjp-81605	128	7	crt2	crt2	NOUN
bjp-81605	128	8	bound	bind	VERB
bjp-81605	128	9	to	to	ADP
bjp-81605	128	10	the	the	DET
bjp-81605	128	11	structure	structure	NOUN
bjp-81605	128	12	,	,	PUNCT
bjp-81605	128	13	its	its	PRON
bjp-81605	128	14	overall	overall	ADJ
bjp-81605	128	15	flexibility	flexibility	NOUN
bjp-81605	128	16	decreased	decrease	VERB
bjp-81605	128	17	(	(	PUNCT
bjp-81605	128	18	figure	figure	NOUN
bjp-81605	128	19	2d	2d	NOUN
bjp-81605	128	20	)	)	PUNCT
bjp-81605	128	21	.	.	PUNCT
bjp-81605	129	1	interaction	interaction	NOUN
bjp-81605	129	2	assessment	assessment	NOUN
bjp-81605	129	3	in	in	ADP
bjp-81605	129	4	vegfr1	vegfr1	NOUN
bjp-81605	129	5	ht-116	ht-116	PROPN
bjp-81605	129	6	cells	cell	NOUN
bjp-81605	129	7	were	be	AUX
bjp-81605	129	8	exposed	expose	VERB
bjp-81605	129	9	to	to	ADP
bjp-81605	129	10	multiple	multiple	ADJ
bjp-81605	129	11	doses	dose	NOUN
bjp-81605	129	12	of	of	ADP
bjp-81605	129	13	either	either	CCONJ
bjp-81605	129	14	fitc	fitc	PROPN
bjp-81605	129	15	-	-	PUNCT
bjp-81605	129	16	conjugated	conjugate	VERB
bjp-81605	129	17	scr	scr	NOUN
bjp-81605	129	18	-	-	PUNCT
bjp-81605	129	19	peptide	peptide	NOUN
bjp-81605	129	20	(	(	PUNCT
bjp-81605	129	21	0.6	0.6	NUM
bjp-81605	129	22	μm	μm	NUM
bjp-81605	129	23	)	)	PUNCT
bjp-81605	129	24	or	or	CCONJ
bjp-81605	129	25	fluorescein	fluorescein	NOUN
bjp-81605	129	26	isothiocyanate	isothiocyanate	NOUN
bjp-81605	129	27	(	(	PUNCT
bjp-81605	129	28	fitc)-conjugated	fitc)-conjugated	PROPN
bjp-81605	129	29	crt2	crt2	PROPN
bjp-81605	129	30	(	(	PUNCT
bjp-81605	129	31	0.35	0.35	NUM
bjp-81605	129	32	and	and	CCONJ
bjp-81605	129	33	0.75	0.75	NUM
bjp-81605	129	34	μm	μm	NUM
bjp-81605	129	35	)	)	PUNCT
bjp-81605	129	36	to	to	PART
bjp-81605	129	37	assess	assess	VERB
bjp-81605	129	38	the	the	DET
bjp-81605	129	39	crt2	crt2	PROPN
bjp-81605	129	40	peptide	peptide	NOUN
bjp-81605	129	41	's	's	PART
bjp-81605	129	42	ability	ability	NOUN
bjp-81605	129	43	for	for	ADP
bjp-81605	129	44	cell	cell	NOUN
bjp-81605	129	45	-	-	PUNCT
bjp-81605	129	46	surface	surface	NOUN
bjp-81605	129	47	binding	binding	NOUN
bjp-81605	129	48	.	.	PUNCT
bjp-81605	130	1	in	in	ADP
bjp-81605	130	2	contrast	contrast	NOUN
bjp-81605	130	3	to	to	ADP
bjp-81605	130	4	the	the	DET
bjp-81605	130	5	control	control	NOUN
bjp-81605	130	6	ht-116	ht-116	PROPN
bjp-81605	130	7	cells	cell	NOUN
bjp-81605	130	8	and	and	CCONJ
bjp-81605	130	9	scrpeptide	scrpeptide	VERB
bjp-81605	130	10	,	,	PUNCT
bjp-81605	130	11	as	as	SCONJ
bjp-81605	130	12	demonstrated	demonstrate	VERB
bjp-81605	130	13	in	in	ADP
bjp-81605	130	14	figure	figure	NOUN
bjp-81605	130	15	3a	3a	NUM
bjp-81605	130	16	.	.	PUNCT
bjp-81605	131	1	the	the	DET
bjp-81605	131	2	fluorescence	fluorescence	NOUN
bjp-81605	131	3	intensity	intensity	NOUN
bjp-81605	131	4	rose	rise	VERB
bjp-81605	131	5	greatly	greatly	ADV
bjp-81605	131	6	as	as	SCONJ
bjp-81605	131	7	the	the	DET
bjp-81605	131	8	concentration	concentration	NOUN
bjp-81605	131	9	of	of	ADP
bjp-81605	131	10	fitc	fitc	PROPN
bjp-81605	131	11	-crt2	-crt2	PROPN
bjp-81605	131	12	increased	increase	VERB
bjp-81605	131	13	.	.	PUNCT
bjp-81605	132	1	to	to	PART
bjp-81605	132	2	determine	determine	VERB
bjp-81605	132	3	if	if	SCONJ
bjp-81605	132	4	crt2	crt2	NOUN
bjp-81605	132	5	binding	bind	VERB
bjp-81605	132	6	was	be	AUX
bjp-81605	132	7	due	due	ADJ
bjp-81605	132	8	to	to	ADP
bjp-81605	132	9	vegf	vegf	NOUN
bjp-81605	132	10	receptors	receptor	NOUN
bjp-81605	132	11	,	,	PUNCT
bjp-81605	132	12	ht-116	ht-116	PROPN
bjp-81605	132	13	cells	cell	NOUN
bjp-81605	132	14	were	be	AUX
bjp-81605	132	15	treated	treat	VERB
bjp-81605	132	16	with	with	ADP
bjp-81605	132	17	anti	anti	ADJ
bjp-81605	132	18	-	-	ADJ
bjp-81605	132	19	vegfr1	vegfr1	ADJ
bjp-81605	132	20	primary	primary	ADJ
bjp-81605	132	21	antibody	antibody	NOUN
bjp-81605	132	22	,	,	PUNCT
bjp-81605	132	23	phycoerythrin	phycoerythrin	NOUN
bjp-81605	132	24	(	(	PUNCT
bjp-81605	132	25	pe)labeled	pe)labele	VERB
bjp-81605	132	26	as	as	ADP
bjp-81605	132	27	antibody	antibody	NOUN
bjp-81605	132	28	and	and	CCONJ
bjp-81605	132	29	fitc	fitc	NOUN
bjp-81605	132	30	-	-	PUNCT
bjp-81605	132	31	labeled	label	VERB
bjp-81605	132	32	as	as	ADP
bjp-81605	132	33	rabbit	rabbit	NOUN
bjp-81605	132	34	antimouse	antimouse	ADP
bjp-81605	132	35	igg	igg	PROPN
bjp-81605	132	36	secondary	secondary	ADJ
bjp-81605	132	37	antibody	antibody	NOUN
bjp-81605	132	38	that	that	PRON
bjp-81605	132	39	increases	increase	VERB
bjp-81605	132	40	the	the	DET
bjp-81605	132	41	concentration	concentration	NOUN
bjp-81605	132	42	in	in	ADP
bjp-81605	132	43	crt2	crt2	PROPN
bjp-81605	132	44	(	(	PUNCT
bjp-81605	132	45	0.33	0.33	NUM
bjp-81605	132	46	,	,	PUNCT
bjp-81605	132	47	0.75	0.75	NUM
bjp-81605	132	48	μm	μm	NUM
bjp-81605	132	49	)	)	PUNCT
bjp-81605	132	50	,	,	PUNCT
bjp-81605	132	51	or	or	CCONJ
bjp-81605	132	52	scr	scr	NOUN
bjp-81605	132	53	(	(	PUNCT
bjp-81605	132	54	0.6	0.6	NUM
bjp-81605	132	55	μm	μm	NUM
bjp-81605	132	56	)	)	PUNCT
bjp-81605	132	57	.	.	PUNCT
bjp-81605	133	1	as	as	SCONJ
bjp-81605	133	2	demonstrated	demonstrate	VERB
bjp-81605	133	3	in	in	ADP
bjp-81605	133	4	(	(	PUNCT
bjp-81605	133	5	figure	figure	NOUN
bjp-81605	133	6	3b	3b	NUM
bjp-81605	133	7	)	)	PUNCT
bjp-81605	133	8	,	,	PUNCT
bjp-81605	133	9	incubation	incubation	NOUN
bjp-81605	133	10	with	with	ADP
bjp-81605	133	11	crt2	crt2	PROPN
bjp-81605	133	12	led	lead	VERB
bjp-81605	133	13	to	to	ADP
bjp-81605	133	14	a	a	DET
bjp-81605	133	15	considerable	considerable	ADJ
bjp-81605	133	16	dose	dose	NOUN
bjp-81605	133	17	-	-	PUNCT
bjp-81605	133	18	dependent	dependent	ADJ
bjp-81605	133	19	reduction	reduction	NOUN
bjp-81605	133	20	in	in	ADP
bjp-81605	133	21	fluorescence	fluorescence	NOUN
bjp-81605	133	22	signals	signal	NOUN
bjp-81605	133	23	when	when	SCONJ
bjp-81605	133	24	compared	compare	VERB
bjp-81605	133	25	to	to	ADP
bjp-81605	133	26	the	the	DET
bjp-81605	133	27	control	control	NOUN
bjp-81605	133	28	and	and	CCONJ
bjp-81605	133	29	scr	scr	NOUN
bjp-81605	133	30	peptide	peptide	NOUN
bjp-81605	133	31	(	(	PUNCT
bjp-81605	133	32	0.6	0.6	NUM
bjp-81605	133	33	μm	μm	NUM
bjp-81605	133	34	)	)	PUNCT
bjp-81605	133	35	.	.	PUNCT
bjp-81605	134	1	this	this	DET
bjp-81605	134	2	result	result	NOUN
bjp-81605	134	3	shows	show	VERB
bjp-81605	134	4	that	that	SCONJ
bjp-81605	134	5	the	the	DET
bjp-81605	134	6	crt2	crt2	PROPN
bjp-81605	134	7	can	can	AUX
bjp-81605	134	8	bind	bind	VERB
bjp-81605	134	9	to	to	ADP
bjp-81605	134	10	vegfr1	vegfr1	NOUN
bjp-81605	134	11	on	on	ADP
bjp-81605	134	12	the	the	DET
bjp-81605	134	13	surface	surface	NOUN
bjp-81605	134	14	of	of	ADP
bjp-81605	134	15	epithelial	epithelial	ADJ
bjp-81605	134	16	cells	cell	NOUN
bjp-81605	134	17	and	and	CCONJ
bjp-81605	134	18	compete	compete	VERB
bjp-81605	134	19	with	with	ADP
bjp-81605	134	20	antibodies	antibody	NOUN
bjp-81605	134	21	that	that	PRON
bjp-81605	134	22	recognize	recognize	VERB
bjp-81605	134	23	the	the	DET
bjp-81605	134	24	extracellular	extracellular	ADJ
bjp-81605	134	25	domains	domain	NOUN
bjp-81605	134	26	of	of	ADP
bjp-81605	134	27	the	the	DET
bjp-81605	134	28	receptors	receptor	NOUN
bjp-81605	134	29	.	.	PUNCT
bjp-81605	135	1	it	it	PRON
bjp-81605	135	2	was	be	AUX
bjp-81605	135	3	verified	verify	VERB
bjp-81605	135	4	by	by	ADP
bjp-81605	135	5	fluorescence	fluorescence	NOUN
bjp-81605	135	6	microscopy	microscopy	NOUN
bjp-81605	135	7	that	that	SCONJ
bjp-81605	135	8	crt2	crt2	PROPN
bjp-81605	135	9	was	be	AUX
bjp-81605	135	10	able	able	ADJ
bjp-81605	135	11	to	to	PART
bjp-81605	135	12	adhere	adhere	VERB
bjp-81605	135	13	to	to	ADP
bjp-81605	135	14	vegfr1	vegfr1	NOUN
bjp-81605	135	15	on	on	ADP
bjp-81605	135	16	the	the	DET
bjp-81605	135	17	surface	surface	NOUN
bjp-81605	135	18	of	of	ADP
bjp-81605	135	19	epithelial	epithelial	ADJ
bjp-81605	135	20	cells	cell	NOUN
bjp-81605	135	21	.	.	PUNCT
bjp-81605	136	1	ht-116	ht-116	PROPN
bjp-81605	136	2	cells	cell	NOUN
bjp-81605	136	3	were	be	AUX
bjp-81605	136	4	treated	treat	VERB
bjp-81605	136	5	with	with	ADP
bjp-81605	136	6	crt2	crt2	PROPN
bjp-81605	136	7	at	at	ADP
bjp-81605	136	8	different	different	ADJ
bjp-81605	136	9	doses	dose	NOUN
bjp-81605	136	10	(	(	PUNCT
bjp-81605	136	11	0.35	0.35	NUM
bjp-81605	136	12	and	and	CCONJ
bjp-81605	136	13	0.75	0.75	NUM
bjp-81605	136	14	μm	μm	NUM
bjp-81605	136	15	)	)	PUNCT
bjp-81605	136	16	,	,	PUNCT
bjp-81605	136	17	and	and	CCONJ
bjp-81605	136	18	then	then	ADV
bjp-81605	136	19	pe	pe	VERB
bjp-81605	136	20	-	-	PUNCT
bjp-81605	136	21	labeled	label	VERB
bjp-81605	136	22	goat	goat	PROPN
bjp-81605	136	23	anti	anti	PROPN
bjp-81605	136	24	-	-	ADJ
bjp-81605	136	25	mouse	mouse	ADJ
bjp-81605	136	26	igg	igg	PROPN
bjp-81605	136	27	secondary	secondary	ADJ
bjp-81605	136	28	antibodies	antibody	NOUN
bjp-81605	136	29	and	and	CCONJ
bjp-81605	136	30	anti	anti	ADJ
bjp-81605	136	31	-	-	ADJ
bjp-81605	136	32	vegfr1	vegfr1	ADJ
bjp-81605	136	33	primary	primary	ADJ
bjp-81605	136	34	antibodies	antibody	NOUN
bjp-81605	136	35	were	be	AUX
bjp-81605	136	36	added	add	VERB
bjp-81605	136	37	.	.	PUNCT
bjp-81605	137	1	fluorescence	fluorescence	PROPN
bjp-81605	137	2	intensity	intensity	NOUN
bjp-81605	137	3	was	be	AUX
bjp-81605	137	4	lowered	lower	VERB
bjp-81605	137	5	by	by	ADP
bjp-81605	137	6	crt2	crt2	PROPN
bjp-81605	137	7	in	in	ADP
bjp-81605	137	8	a	a	DET
bjp-81605	137	9	dose	dose	NOUN
bjp-81605	137	10	-	-	PUNCT
bjp-81605	137	11	dependent	dependent	ADJ
bjp-81605	137	12	manner	manner	NOUN
bjp-81605	137	13	.	.	PUNCT
bjp-81605	138	1	only	only	ADV
bjp-81605	138	2	8	8	NUM
bjp-81605	138	3	%	%	NOUN
bjp-81605	138	4	reduction	reduction	NOUN
bjp-81605	138	5	at	at	ADP
bjp-81605	138	6	0.75	0.75	NUM
bjp-81605	138	7	μm	μm	NUM
bjp-81605	138	8	concentration	concentration	NOUN
bjp-81605	138	9	,	,	PUNCT
bjp-81605	138	10	while	while	SCONJ
bjp-81605	138	11	78	78	NUM
bjp-81605	138	12	%	%	NOUN
bjp-81605	138	13	in	in	ADP
bjp-81605	138	14	the	the	DET
bjp-81605	138	15	control	control	NOUN
bjp-81605	138	16	.	.	PUNCT
bjp-81605	139	1	this	this	DET
bjp-81605	139	2	result	result	NOUN
bjp-81605	139	3	validates	validate	VERB
bjp-81605	139	4	the	the	DET
bjp-81605	139	5	crt2	crt2	PROPN
bjp-81605	139	6	's	's	PART
bjp-81605	139	7	ability	ability	NOUN
bjp-81605	139	8	to	to	PART
bjp-81605	139	9	recognize	recognize	VERB
bjp-81605	139	10	vegfr1	vegfr1	NOUN
bjp-81605	139	11	.	.	PUNCT
bjp-81605	140	1	to	to	PART
bjp-81605	140	2	confirm	confirm	VERB
bjp-81605	140	3	further	further	ADJ
bjp-81605	140	4	crt2	crt2	PROPN
bjp-81605	140	5	's	's	PART
bjp-81605	140	6	vegfr1	vegfr1	NOUN
bjp-81605	140	7	binding	bind	VERB
bjp-81605	140	8	characteristics	characteristic	NOUN
bjp-81605	140	9	,	,	PUNCT
bjp-81605	140	10	it	it	PRON
bjp-81605	140	11	is	be	AUX
bjp-81605	140	12	demonstrated	demonstrate	VERB
bjp-81605	140	13	in	in	ADP
bjp-81605	140	14	that	that	SCONJ
bjp-81605	140	15	the	the	DET
bjp-81605	140	16	highly	highly	ADV
bjp-81605	140	17	expressed	express	VERB
bjp-81605	140	18	vegfr1	vegfr1	NOUN
bjp-81605	140	19	colorectal	colorectal	ADJ
bjp-81605	140	20	cancer	cancer	NOUN
bjp-81605	140	21	ht-116	ht-116	PROPN
bjp-81605	140	22	cell	cell	NOUN
bjp-81605	140	23	lines	line	NOUN
bjp-81605	140	24	have	have	AUX
bjp-81605	140	25	suppressed	suppress	VERB
bjp-81605	140	26	their	their	PRON
bjp-81605	140	27	growth	growth	NOUN
bjp-81605	140	28	.	.	PUNCT
bjp-81605	141	1	figure	figure	NOUN
bjp-81605	141	2	2	2	NUM
bjp-81605	141	3	:	:	PUNCT
bjp-81605	141	4	the	the	DET
bjp-81605	141	5	docked	dock	VERB
bjp-81605	141	6	conformation	conformation	NOUN
bjp-81605	141	7	indicates	indicate	VERB
bjp-81605	141	8	that	that	SCONJ
bjp-81605	141	9	the	the	DET
bjp-81605	141	10	water	water	NOUN
bjp-81605	141	11	-	-	PUNCT
bjp-81605	141	12	mediated	mediate	VERB
bjp-81605	141	13	interactions	interaction	NOUN
bjp-81605	141	14	are	be	AUX
bjp-81605	141	15	supporting	support	VERB
bjp-81605	141	16	crt2	crt2	NOUN
bjp-81605	141	17	binding	bind	VERB
bjp-81605	141	18	(	(	PUNCT
bjp-81605	141	19	a	a	NOUN
bjp-81605	141	20	)	)	PUNCT
bjp-81605	141	21	.	.	PUNCT
bjp-81605	142	1	using	use	VERB
bjp-81605	142	2	vegfr1	vegfr1	NOUN
bjp-81605	142	3	to	to	PART
bjp-81605	142	4	bind	bind	VERB
bjp-81605	142	5	the	the	DET
bjp-81605	142	6	free	free	ADJ
bjp-81605	142	7	energy	energy	NOUN
bjp-81605	142	8	component	component	NOUN
bjp-81605	142	9	of	of	ADP
bjp-81605	142	10	crt2	crt2	PROPN
bjp-81605	142	11	according	accord	VERB
bjp-81605	142	12	to	to	ADP
bjp-81605	142	13	mmpbsa	mmpbsa	NOUN
bjp-81605	142	14	calculations	calculation	NOUN
bjp-81605	142	15	(	(	PUNCT
bjp-81605	142	16	b	b	NOUN
bjp-81605	142	17	)	)	PUNCT
bjp-81605	142	18	.	.	PUNCT
bjp-81605	143	1	the	the	DET
bjp-81605	143	2	crt2	crt2	PROPN
bjp-81605	143	3	-	-	PUNCT
bjp-81605	143	4	vegfr1	vegfr1	NOUN
bjp-81605	143	5	complex	complex	NOUN
bjp-81605	143	6	and	and	CCONJ
bjp-81605	143	7	the	the	DET
bjp-81605	143	8	protein	protein	NOUN
bjp-81605	143	9	vegfr1	vegfr1	PROPN
bjp-81605	143	10	's	's	PART
bjp-81605	143	11	root	root	NOUN
bjp-81605	143	12	mean	mean	NOUN
bjp-81605	143	13	square	square	ADJ
bjp-81605	143	14	displacement	displacement	NOUN
bjp-81605	143	15	(	(	PUNCT
bjp-81605	143	16	rmsd	rmsd	PROPN
bjp-81605	143	17	)	)	PUNCT
bjp-81605	143	18	(	(	PUNCT
bjp-81605	143	19	c	c	NOUN
bjp-81605	143	20	)	)	PUNCT
bjp-81605	143	21	.	.	PUNCT
bjp-81605	144	1	b	b	X
bjp-81605	144	2	-	-	PUNCT
bjp-81605	144	3	factor	factor	NOUN
bjp-81605	144	4	analysis	analysis	NOUN
bjp-81605	144	5	indicates	indicate	VERB
bjp-81605	144	6	that	that	SCONJ
bjp-81605	144	7	the	the	DET
bjp-81605	144	8	upon	upon	ADJ
bjp-81605	144	9	contact	contact	NOUN
bjp-81605	144	10	with	with	ADP
bjp-81605	144	11	crt2	crt2	PROPN
bjp-81605	144	12	,	,	PUNCT
bjp-81605	144	13	protein	protein	NOUN
bjp-81605	144	14	flexibility	flexibility	NOUN
bjp-81605	144	15	declines	decline	VERB
bjp-81605	144	16	(	(	PUNCT
bjp-81605	144	17	d	d	NOUN
bjp-81605	144	18	)	)	PUNCT
bjp-81605	144	19	.	.	PUNCT
bjp-81605	145	1	the	the	DET
bjp-81605	145	2	abbreviations	abbreviation	NOUN
bjp-81605	145	3	are	be	AUX
bjp-81605	145	4	evander	evander	NOUN
bjp-81605	145	5	walls	wall	NOUN
bjp-81605	145	6	:	:	PUNCT
bjp-81605	145	7	non	non	ADJ
bjp-81605	145	8	-	-	ADJ
bjp-81605	145	9	bonded	bonded	ADJ
bjp-81605	145	10	van	van	PROPN
bjp-81605	145	11	der	der	NOUN
bjp-81605	145	12	waals	waal	NOUN
bjp-81605	145	13	energy	energy	NOUN
bjp-81605	145	14	;	;	PUNCT
bjp-81605	145	15	eeel	eeel	ADJ
bjp-81605	145	16	:	:	PUNCT
bjp-81605	145	17	non	non	ADJ
bjp-81605	145	18	-	-	ADJ
bjp-81605	145	19	bonded	bond	VERB
bjp-81605	145	20	electrostatic	electrostatic	ADJ
bjp-81605	145	21	energy	energy	NOUN
bjp-81605	145	22	;	;	PUNCT
bjp-81605	145	23	epb	epb	PROPN
bjp-81605	145	24	:	:	PUNCT
bjp-81605	145	25	energy	energy	NOUN
bjp-81605	145	26	of	of	ADP
bjp-81605	145	27	polar	polar	ADJ
bjp-81605	145	28	solvation	solvation	NOUN
bjp-81605	145	29	(	(	PUNCT
bjp-81605	145	30	pb	pb	PROPN
bjp-81605	145	31	)	)	PUNCT
bjp-81605	145	32	;	;	PUNCT
bjp-81605	145	33	enpolar	enpolar	ADJ
bjp-81605	145	34	:	:	PUNCT
bjp-81605	145	35	repulsive	repulsive	ADJ
bjp-81605	145	36	solute	solute	ADJ
bjp-81605	145	37	-	-	PUNCT
bjp-81605	145	38	solvent	solvent	ADJ
bjp-81605	145	39	interactions	interaction	NOUN
bjp-81605	145	40	(	(	PUNCT
bjp-81605	145	41	pb	pb	X
bjp-81605	145	42	)	)	PUNCT
bjp-81605	145	43	that	that	PRON
bjp-81605	145	44	produce	produce	VERB
bjp-81605	145	45	nonpolar	nonpolar	ADJ
bjp-81605	145	46	solvation	solvation	NOUN
bjp-81605	145	47	energy	energy	NOUN
bjp-81605	145	48	;	;	PUNCT
bjp-81605	145	49	∆ggas	∆gga	NOUN
bjp-81605	145	50	:	:	PUNCT
bjp-81605	145	51	internal	internal	ADJ
bjp-81605	145	52	energy	energy	NOUN
bjp-81605	145	53	+	+	CCONJ
bjp-81605	145	54	eeel	eeel	ADJ
bjp-81605	145	55	+	+	NUM
bjp-81605	145	56	evdwaals	evdwaal	NOUN
bjp-81605	145	57	;	;	PUNCT
bjp-81605	145	58	∆gsolv	∆gsolv	NUM
bjp-81605	145	59	:	:	PUNCT
bjp-81605	145	60	polar	polar	ADJ
bjp-81605	145	61	solvation	solvation	NOUN
bjp-81605	145	62	energy	energy	NOUN
bjp-81605	145	63	plus	plus	CCONJ
bjp-81605	145	64	non	non	ADJ
bjp-81605	145	65	-	-	ADJ
bjp-81605	145	66	polar	polar	ADJ
bjp-81605	145	67	solvation	solvation	NOUN
bjp-81605	145	68	energy	energy	NOUN
bjp-81605	145	69	equals	equal	VERB
bjp-81605	145	70	;	;	PUNCT
bjp-81605	145	71	∆ggas+∆gsolv	∆ggas+∆gsolv	ADV
bjp-81605	145	72	:	:	PUNCT
bjp-81605	145	73	binding	bind	VERB
bjp-81605	145	74	free	free	ADJ
bjp-81605	145	75	energy	energy	NOUN
bjp-81605	145	76	is	be	AUX
bjp-81605	145	77	binding	bind	VERB
bjp-81605	145	78	energy	energy	NOUN
bjp-81605	145	79	c	c	PROPN
bjp-81605	145	80	b	b	PROPN
bjp-81605	145	81	a	a	DET
bjp-81605	145	82	d	d	X
bjp-81605	145	83	bangladesh	bangladesh	PROPN
bjp-81605	145	84	j	j	PROPN
bjp-81605	145	85	pharmacol	pharmacol	PROPN
bjp-81605	145	86	2025	2025	NUM
bjp-81605	145	87	;	;	PUNCT
bjp-81605	145	88	20	20	NUM
bjp-81605	145	89	:	:	SYM
bjp-81605	145	90	89	89	NUM
bjp-81605	145	91	-	-	SYM
bjp-81605	145	92	100	100	NUM
bjp-81605	145	93	93	93	NUM
bjp-81605	145	94	cell	cell	NOUN
bjp-81605	145	95	proliferation	proliferation	NOUN
bjp-81605	145	96	,	,	PUNCT
bjp-81605	145	97	morphological	morphological	ADJ
bjp-81605	145	98	changes	change	NOUN
bjp-81605	145	99	,	,	PUNCT
bjp-81605	145	100	and	and	CCONJ
bjp-81605	145	101	cell	cell	NOUN
bjp-81605	145	102	invasion	invasion	NOUN
bjp-81605	145	103	we	we	PRON
bjp-81605	145	104	chose	choose	VERB
bjp-81605	145	105	the	the	DET
bjp-81605	145	106	in	in	ADV
bjp-81605	145	107	vitro	vitro	X
bjp-81605	145	108	cell	cell	NOUN
bjp-81605	145	109	model	model	NOUN
bjp-81605	145	110	to	to	PART
bjp-81605	145	111	study	study	VERB
bjp-81605	145	112	the	the	DET
bjp-81605	145	113	cytotoxic	cytotoxic	ADJ
bjp-81605	145	114	effects	effect	NOUN
bjp-81605	145	115	of	of	ADP
bjp-81605	145	116	crt2	crt2	PROPN
bjp-81605	145	117	on	on	ADP
bjp-81605	145	118	colorectal	colorectal	ADJ
bjp-81605	145	119	cancer	cancer	NOUN
bjp-81605	145	120	vegfr1	vegfr1	NOUN
bjp-81605	145	121	+	+	CCONJ
bjp-81605	145	122	ht-116	ht-116	NOUN
bjp-81605	145	123	cell	cell	NOUN
bjp-81605	145	124	lines	line	NOUN
bjp-81605	145	125	.	.	PUNCT
bjp-81605	146	1	these	these	PRON
bjp-81605	146	2	were	be	AUX
bjp-81605	146	3	exposed	expose	VERB
bjp-81605	146	4	to	to	ADP
bjp-81605	146	5	varying	vary	VERB
bjp-81605	146	6	doses	dose	NOUN
bjp-81605	146	7	of	of	ADP
bjp-81605	146	8	crt2	crt2	PROPN
bjp-81605	146	9	for	for	ADP
bjp-81605	146	10	24	24	NUM
bjp-81605	146	11	to	to	PART
bjp-81605	146	12	48	48	NUM
bjp-81605	146	13	hours	hour	NOUN
bjp-81605	146	14	.	.	PUNCT
bjp-81605	147	1	crt2	crt2	PROPN
bjp-81605	147	2	effectively	effectively	ADV
bjp-81605	147	3	stopped	stop	VERB
bjp-81605	147	4	the	the	DET
bjp-81605	147	5	proliferation	proliferation	NOUN
bjp-81605	147	6	of	of	ADP
bjp-81605	147	7	colorectal	colorectal	ADJ
bjp-81605	147	8	cancer	cancer	NOUN
bjp-81605	147	9	cell	cell	NOUN
bjp-81605	147	10	lines	line	NOUN
bjp-81605	147	11	(	(	PUNCT
bjp-81605	147	12	figure	figure	NOUN
bjp-81605	147	13	4a	4a	NUM
bjp-81605	147	14	-	-	PUNCT
bjp-81605	147	15	b	b	NOUN
bjp-81605	147	16	)	)	PUNCT
bjp-81605	147	17	.	.	PUNCT
bjp-81605	148	1	the	the	DET
bjp-81605	148	2	half	half	ADJ
bjp-81605	148	3	-	-	PUNCT
bjp-81605	148	4	maximum	maximum	ADJ
bjp-81605	148	5	inhibitory	inhibitory	ADJ
bjp-81605	148	6	concentration	concentration	NOUN
bjp-81605	148	7	(	(	PUNCT
bjp-81605	148	8	ic50	ic50	PROPN
bjp-81605	148	9	)	)	PUNCT
bjp-81605	148	10	of	of	ADP
bjp-81605	148	11	crt2	crt2	PROPN
bjp-81605	148	12	for	for	ADP
bjp-81605	148	13	ht-116	ht-116	PROPN
bjp-81605	148	14	cells	cell	NOUN
bjp-81605	148	15	was	be	AUX
bjp-81605	148	16	16.0	16.0	NUM
bjp-81605	148	17	±	±	NUM
bjp-81605	148	18	1.3	1.3	NUM
bjp-81605	148	19	μg	μg	NOUN
bjp-81605	148	20	/	/	SYM
bjp-81605	148	21	ml	ml	NOUN
bjp-81605	148	22	,	,	PUNCT
bjp-81605	148	23	respectively	respectively	ADV
bjp-81605	148	24	.	.	PUNCT
bjp-81605	149	1	the	the	DET
bjp-81605	149	2	crt2	crt2	PROPN
bjp-81605	149	3	peptide	peptide	NOUN
bjp-81605	149	4	demonstrated	demonstrate	VERB
bjp-81605	149	5	a	a	DET
bjp-81605	149	6	broad	broad	ADJ
bjp-81605	149	7	spectrum	spectrum	NOUN
bjp-81605	149	8	of	of	ADP
bjp-81605	149	9	cell	cell	NOUN
bjp-81605	149	10	inhibition	inhibition	NOUN
bjp-81605	149	11	in	in	ADP
bjp-81605	149	12	a	a	DET
bjp-81605	149	13	doseor	doseor	NOUN
bjp-81605	149	14	time	time	NOUN
bjp-81605	149	15	-	-	PUNCT
bjp-81605	149	16	dependent	dependent	ADJ
bjp-81605	149	17	manner	manner	NOUN
bjp-81605	149	18	in	in	ADP
bjp-81605	149	19	several	several	ADJ
bjp-81605	149	20	colorectal	colorectal	ADJ
bjp-81605	149	21	cancer	cancer	NOUN
bjp-81605	149	22	cell	cell	NOUN
bjp-81605	149	23	lines	line	NOUN
bjp-81605	149	24	.	.	PUNCT
bjp-81605	150	1	the	the	DET
bjp-81605	150	2	peptide	peptide	NOUN
bjp-81605	150	3	contains	contain	VERB
bjp-81605	150	4	six	six	NUM
bjp-81605	150	5	positively	positively	ADV
bjp-81605	150	6	charged	charge	VERB
bjp-81605	150	7	residues	residue	NOUN
bjp-81605	150	8	that	that	PRON
bjp-81605	150	9	make	make	VERB
bjp-81605	150	10	up	up	ADP
bjp-81605	150	11	a	a	DET
bjp-81605	150	12	crt2	crt2	NOUN
bjp-81605	150	13	peptide	peptide	NOUN
bjp-81605	150	14	,	,	PUNCT
bjp-81605	150	15	which	which	PRON
bjp-81605	150	16	is	be	AUX
bjp-81605	150	17	soluble	soluble	ADJ
bjp-81605	150	18	in	in	ADP
bjp-81605	150	19	water	water	NOUN
bjp-81605	150	20	.	.	PUNCT
bjp-81605	151	1	one	one	NUM
bjp-81605	151	2	side	side	NOUN
bjp-81605	151	3	of	of	ADP
bjp-81605	151	4	the	the	DET
bjp-81605	151	5	helix	helix	NOUN
bjp-81605	151	6	,	,	PUNCT
bjp-81605	151	7	methionine	methionine	NOUN
bjp-81605	151	8	(	(	PUNCT
bjp-81605	151	9	w	w	NOUN
bjp-81605	151	10	)	)	PUNCT
bjp-81605	151	11	,	,	PUNCT
bjp-81605	151	12	is	be	AUX
bjp-81605	151	13	hydrophobic	hydrophobic	NOUN
bjp-81605	151	14	,	,	PUNCT
bjp-81605	151	15	and	and	CCONJ
bjp-81605	151	16	the	the	DET
bjp-81605	151	17	other	other	ADJ
bjp-81605	151	18	side	side	NOUN
bjp-81605	151	19	of	of	ADP
bjp-81605	151	20	the	the	DET
bjp-81605	151	21	helix	helix	NOUN
bjp-81605	151	22	,	,	PUNCT
bjp-81605	151	23	h	h	NOUN
bjp-81605	151	24	,	,	PUNCT
bjp-81605	151	25	is	be	AUX
bjp-81605	151	26	polar	polar	ADJ
bjp-81605	151	27	and	and	CCONJ
bjp-81605	151	28	hydrophilic	hydrophilic	ADJ
bjp-81605	151	29	amino	amino	NOUN
bjp-81605	151	30	acids	acid	NOUN
bjp-81605	151	31	.	.	PUNCT
bjp-81605	152	1	this	this	PRON
bjp-81605	152	2	is	be	AUX
bjp-81605	152	3	where	where	SCONJ
bjp-81605	152	4	the	the	DET
bjp-81605	152	5	crt2	crt2	PROPN
bjp-81605	152	6	peptide	peptide	NOUN
bjp-81605	152	7	is	be	AUX
bjp-81605	152	8	located	locate	VERB
bjp-81605	152	9	.	.	PUNCT
bjp-81605	153	1	it	it	PRON
bjp-81605	153	2	is	be	AUX
bjp-81605	153	3	known	know	VERB
bjp-81605	153	4	that	that	SCONJ
bjp-81605	153	5	these	these	DET
bjp-81605	153	6	cationic	cationic	ADJ
bjp-81605	153	7	amphipathic	amphipathic	ADJ
bjp-81605	153	8	peptides	peptide	NOUN
bjp-81605	153	9	can	can	AUX
bjp-81605	153	10	cause	cause	VERB
bjp-81605	153	11	membrane	membrane	NOUN
bjp-81605	153	12	instability	instability	NOUN
bjp-81605	153	13	and	and	CCONJ
bjp-81605	153	14	cause	cause	VERB
bjp-81605	153	15	cancer	cancer	NOUN
bjp-81605	153	16	cells	cell	NOUN
bjp-81605	153	17	to	to	PART
bjp-81605	153	18	die	die	VERB
bjp-81605	153	19	.	.	PUNCT
bjp-81605	154	1	it	it	PRON
bjp-81605	154	2	had	have	AUX
bjp-81605	154	3	been	be	AUX
bjp-81605	154	4	discovered	discover	VERB
bjp-81605	154	5	that	that	SCONJ
bjp-81605	154	6	peptides	peptide	NOUN
bjp-81605	154	7	containing	contain	VERB
bjp-81605	154	8	serine	serine	NOUN
bjp-81605	154	9	caused	cause	VERB
bjp-81605	154	10	cell	cell	NOUN
bjp-81605	154	11	cycle	cycle	NOUN
bjp-81605	154	12	arrest	arrest	NOUN
bjp-81605	154	13	and	and	CCONJ
bjp-81605	154	14	apoptosis	apoptosis	NOUN
bjp-81605	154	15	.	.	PUNCT
bjp-81605	154	16	phase	phase	NOUN
bjp-81605	154	17	-	-	PUNCT
bjp-81605	154	18	contrast	contrast	NOUN
bjp-81605	154	19	microscopy	microscopy	NOUN
bjp-81605	154	20	was	be	AUX
bjp-81605	154	21	used	use	VERB
bjp-81605	154	22	to	to	PART
bjp-81605	154	23	analyze	analyze	VERB
bjp-81605	154	24	the	the	DET
bjp-81605	154	25	morphology	morphology	NOUN
bjp-81605	154	26	of	of	ADP
bjp-81605	154	27	selective	selective	ADJ
bjp-81605	154	28	crt2	crt2	NOUN
bjp-81605	154	29	in	in	ADP
bjp-81605	154	30	human	human	ADJ
bjp-81605	154	31	colon	colon	NOUN
bjp-81605	154	32	cancer	cancer	NOUN
bjp-81605	154	33	cell	cell	NOUN
bjp-81605	154	34	lines	line	NOUN
bjp-81605	154	35	.	.	PUNCT
bjp-81605	155	1	green	green	ADJ
bjp-81605	155	2	light	light	NOUN
bjp-81605	155	3	was	be	AUX
bjp-81605	155	4	emitted	emit	VERB
bjp-81605	155	5	by	by	ADP
bjp-81605	155	6	living	live	VERB
bjp-81605	155	7	,	,	PUNCT
bjp-81605	155	8	viable	viable	ADJ
bjp-81605	155	9	cells	cell	NOUN
bjp-81605	155	10	,	,	PUNCT
bjp-81605	155	11	orange	orange	ADJ
bjp-81605	155	12	-	-	PUNCT
bjp-81605	155	13	yellow	yellow	ADJ
bjp-81605	155	14	light	light	NOUN
bjp-81605	155	15	was	be	AUX
bjp-81605	155	16	emitted	emit	VERB
bjp-81605	155	17	by	by	ADP
bjp-81605	155	18	early	early	ADJ
bjp-81605	155	19	apoptotic	apoptotic	ADJ
bjp-81605	155	20	cells	cell	NOUN
bjp-81605	155	21	,	,	PUNCT
bjp-81605	155	22	and	and	CCONJ
bjp-81605	155	23	red	red	ADJ
bjp-81605	155	24	light	light	NOUN
bjp-81605	155	25	was	be	AUX
bjp-81605	155	26	emitted	emit	VERB
bjp-81605	155	27	by	by	ADP
bjp-81605	155	28	late	late	ADJ
bjp-81605	155	29	apoptosis	apoptosis	NOUN
bjp-81605	155	30	or	or	CCONJ
bjp-81605	155	31	dna	dna	NOUN
bjp-81605	155	32	-	-	PUNCT
bjp-81605	155	33	fragmented	fragment	VERB
bjp-81605	155	34	cells	cell	NOUN
bjp-81605	155	35	(	(	PUNCT
bjp-81605	155	36	figure	figure	NOUN
bjp-81605	155	37	4c	4c	NOUN
bjp-81605	155	38	)	)	PUNCT
bjp-81605	155	39	.	.	PUNCT
bjp-81605	156	1	crt2	crt2	PROPN
bjp-81605	156	2	-	-	PUNCT
bjp-81605	156	3	treated	treat	VERB
bjp-81605	156	4	colorectal	colorectal	ADJ
bjp-81605	156	5	cancer	cancer	NOUN
bjp-81605	156	6	cells	cell	NOUN
bjp-81605	156	7	exhibited	exhibit	VERB
bjp-81605	156	8	an	an	DET
bjp-81605	156	9	increase	increase	NOUN
bjp-81605	156	10	in	in	ADP
bjp-81605	156	11	ht-116	ht-116	NOUN
bjp-81605	156	12	apoptosis	apoptosis	NOUN
bjp-81605	156	13	.	.	PUNCT
bjp-81605	157	1	data	datum	NOUN
bjp-81605	157	2	were	be	AUX
bjp-81605	157	3	synchronized	synchronize	VERB
bjp-81605	157	4	with	with	ADP
bjp-81605	157	5	the	the	DET
bjp-81605	157	6	mtt	mtt	NOUN
bjp-81605	157	7	.	.	PUNCT
bjp-81605	158	1	mitochondrial	mitochondrial	ADJ
bjp-81605	158	2	potential	potential	NOUN
bjp-81605	158	3	against	against	ADP
bjp-81605	158	4	crt2	crt2	PROPN
bjp-81605	158	5	-	-	PUNCT
bjp-81605	158	6	treated	treat	VERB
bjp-81605	158	7	colon	colon	NOUN
bjp-81605	158	8	cancer	cancer	NOUN
bjp-81605	158	9	cell	cell	NOUN
bjp-81605	158	10	lines	line	VERB
bjp-81605	158	11	anti	anti	ADJ
bjp-81605	158	12	-	-	ADJ
bjp-81605	158	13	cancer	cancer	ADJ
bjp-81605	158	14	properties	property	NOUN
bjp-81605	158	15	of	of	ADP
bjp-81605	158	16	crt2	crt2	PROPN
bjp-81605	158	17	peptide	peptide	NOUN
bjp-81605	158	18	were	be	AUX
bjp-81605	158	19	further	far	ADV
bjp-81605	158	20	validated	validate	VERB
bjp-81605	158	21	by	by	ADP
bjp-81605	158	22	this	this	DET
bjp-81605	158	23	assay	assay	NOUN
bjp-81605	158	24	.	.	PUNCT
bjp-81605	159	1	the	the	DET
bjp-81605	159	2	regulation	regulation	NOUN
bjp-81605	159	3	of	of	ADP
bjp-81605	159	4	apoptosis	apoptosis	NOUN
bjp-81605	159	5	was	be	AUX
bjp-81605	159	6	largely	largely	ADV
bjp-81605	159	7	dependent	dependent	ADJ
bjp-81605	159	8	on	on	ADP
bjp-81605	159	9	the	the	DET
bjp-81605	159	10	cell	cell	NOUN
bjp-81605	159	11	apoptosis	apoptosis	NOUN
bjp-81605	159	12	.	.	PUNCT
bjp-81605	160	1	jc-1	jc-1	PROPN
bjp-81605	160	2	,	,	PUNCT
bjp-81605	160	3	a	a	DET
bjp-81605	160	4	monomer	monomer	NOUN
bjp-81605	160	5	that	that	PRON
bjp-81605	160	6	exhibits	exhibit	VERB
bjp-81605	160	7	green	green	ADJ
bjp-81605	160	8	fluorescence	fluorescence	NOUN
bjp-81605	160	9	at	at	ADP
bjp-81605	160	10	em485	em485	PROPN
bjp-81605	160	11	and	and	CCONJ
bjp-81605	160	12	ex535	ex535	PROPN
bjp-81605	160	13	nm	nm	PROPN
bjp-81605	160	14	,	,	PUNCT
bjp-81605	160	15	was	be	AUX
bjp-81605	160	16	used	use	VERB
bjp-81605	160	17	in	in	ADP
bjp-81605	160	18	the	the	DET
bjp-81605	160	19	mmp	mmp	PROPN
bjp-81605	160	20	-	-	ADJ
bjp-81605	160	21	sensitive	sensitive	ADJ
bjp-81605	160	22	fluorescent	fluorescent	NOUN
bjp-81605	160	23	assay	assay	VERB
bjp-81605	160	24	to	to	PART
bjp-81605	160	25	evaluate	evaluate	VERB
bjp-81605	160	26	mmp	mmp	PROPN
bjp-81605	160	27	in	in	ADP
bjp-81605	160	28	the	the	DET
bjp-81605	160	29	context	context	NOUN
bjp-81605	160	30	of	of	ADP
bjp-81605	160	31	crt2	crt2	PROPN
bjp-81605	160	32	therapy	therapy	NOUN
bjp-81605	160	33	.	.	PUNCT
bjp-81605	161	1	in	in	ADP
bjp-81605	161	2	cells	cell	NOUN
bjp-81605	161	3	with	with	ADP
bjp-81605	161	4	greater	great	ADJ
bjp-81605	161	5	mitochondrial	mitochondrial	ADJ
bjp-81605	161	6	potential	potential	NOUN
bjp-81605	161	7	,	,	PUNCT
bjp-81605	161	8	jc-1	jc-1	NOUN
bjp-81605	161	9	fluorochrome	fluorochrome	NOUN
bjp-81605	161	10	accumulated	accumulate	VERB
bjp-81605	161	11	within	within	ADP
bjp-81605	161	12	the	the	DET
bjp-81605	161	13	mitochondrial	mitochondrial	ADJ
bjp-81605	161	14	membrane	membrane	NOUN
bjp-81605	161	15	matrix	matrix	NOUN
bjp-81605	161	16	to	to	PART
bjp-81605	161	17	form	form	VERB
bjp-81605	161	18	jc-1	jc-1	NOUN
bjp-81605	161	19	fluorochrome	fluorochrome	NOUN
bjp-81605	161	20	aggregation	aggregation	NOUN
bjp-81605	161	21	.	.	PUNCT
bjp-81605	162	1	it	it	PRON
bjp-81605	162	2	exhibited	exhibit	VERB
bjp-81605	162	3	red	red	ADJ
bjp-81605	162	4	fluorescence	fluorescence	NOUN
bjp-81605	162	5	with	with	ADP
bjp-81605	162	6	values	value	NOUN
bjp-81605	162	7	of	of	ADP
bjp-81605	162	8	ex560	ex560	PROPN
bjp-81605	162	9	and	and	CCONJ
bjp-81605	162	10	em595	em595	PROPN
bjp-81605	162	11	nm	nm	ADV
bjp-81605	162	12	(	(	PUNCT
bjp-81605	162	13	figure	figure	NOUN
bjp-81605	162	14	5	5	NUM
bjp-81605	162	15	)	)	PUNCT
bjp-81605	162	16	.	.	PUNCT
bjp-81605	163	1	due	due	ADP
bjp-81605	163	2	to	to	ADP
bjp-81605	163	3	monomer	monomer	NOUN
bjp-81605	163	4	aggregates	aggregate	NOUN
bjp-81605	163	5	in	in	ADP
bjp-81605	163	6	the	the	DET
bjp-81605	163	7	mitochondria	mitochondria	NOUN
bjp-81605	163	8	,	,	PUNCT
bjp-81605	163	9	in	in	ADP
bjp-81605	163	10	this	this	DET
bjp-81605	163	11	situation	situation	NOUN
bjp-81605	163	12	,	,	PUNCT
bjp-81605	163	13	which	which	PRON
bjp-81605	163	14	has	have	VERB
bjp-81605	163	15	low	low	ADJ
bjp-81605	163	16	mitochondrial	mitochondrial	ADJ
bjp-81605	163	17	membrane	membrane	NOUN
bjp-81605	163	18	potential	potential	NOUN
bjp-81605	163	19	,	,	PUNCT
bjp-81605	163	20	apoptotic	apoptotic	ADJ
bjp-81605	163	21	cells	cell	NOUN
bjp-81605	163	22	or	or	CCONJ
bjp-81605	163	23	jc-1	jc-1	NOUN
bjp-81605	163	24	fluorochrome	fluorochrome	PROPN
bjp-81605	163	25	continue	continue	VERB
bjp-81605	163	26	to	to	PART
bjp-81605	163	27	develop	develop	VERB
bjp-81605	163	28	.	.	PUNCT
bjp-81605	164	1	consequently	consequently	ADV
bjp-81605	164	2	,	,	PUNCT
bjp-81605	164	3	there	there	PRON
bjp-81605	164	4	is	be	VERB
bjp-81605	164	5	a	a	DET
bjp-81605	164	6	red	red	ADJ
bjp-81605	164	7	shift	shift	NOUN
bjp-81605	164	8	to	to	ADP
bjp-81605	164	9	a	a	DET
bjp-81605	164	10	green	green	ADJ
bjp-81605	164	11	shift	shift	NOUN
bjp-81605	164	12	in	in	ADP
bjp-81605	164	13	the	the	DET
bjp-81605	164	14	fluorescence	fluorescence	NOUN
bjp-81605	164	15	spectrum	spectrum	NOUN
bjp-81605	164	16	extension	extension	NOUN
bjp-81605	164	17	,	,	PUNCT
bjp-81605	164	18	a	a	DET
bjp-81605	164	19	measure	measure	NOUN
bjp-81605	164	20	of	of	ADP
bjp-81605	164	21	mitochondrial	mitochondrial	ADJ
bjp-81605	164	22	depolarization	depolarization	NOUN
bjp-81605	164	23	.	.	PUNCT
bjp-81605	165	1	in	in	ADP
bjp-81605	165	2	both	both	CCONJ
bjp-81605	165	3	control	control	NOUN
bjp-81605	165	4	and	and	CCONJ
bjp-81605	165	5	free	free	ADJ
bjp-81605	165	6	drug	drug	NOUN
bjp-81605	165	7	-	-	PUNCT
bjp-81605	165	8	treated	treat	VERB
bjp-81605	165	9	cells	cell	NOUN
bjp-81605	165	10	,	,	PUNCT
bjp-81605	165	11	the	the	DET
bjp-81605	165	12	mitochondria	mitochondria	NOUN
bjp-81605	165	13	displayed	display	VERB
bjp-81605	165	14	red	red	ADJ
bjp-81605	165	15	fluorescence	fluorescence	NOUN
bjp-81605	165	16	.	.	PUNCT
bjp-81605	166	1	this	this	DET
bjp-81605	166	2	progression	progression	NOUN
bjp-81605	166	3	indicated	indicate	VERB
bjp-81605	166	4	active	active	ADJ
bjp-81605	166	5	mitochondria	mitochondria	NOUN
bjp-81605	166	6	.	.	PUNCT
bjp-81605	167	1	however	however	ADV
bjp-81605	167	2	,	,	PUNCT
bjp-81605	167	3	crt2	crt2	PROPN
bjp-81605	167	4	treatment	treatment	NOUN
bjp-81605	167	5	reduced	reduce	VERB
bjp-81605	167	6	mitochondrial	mitochondrial	ADJ
bjp-81605	167	7	integrity	integrity	NOUN
bjp-81605	167	8	in	in	ADP
bjp-81605	167	9	a	a	DET
bjp-81605	167	10	dose	dose	NOUN
bjp-81605	167	11	-	-	PUNCT
bjp-81605	167	12	dependent	dependent	ADJ
bjp-81605	167	13	manner	manner	NOUN
bjp-81605	167	14	.	.	PUNCT
bjp-81605	168	1	in	in	ADP
bjp-81605	168	2	contrast	contrast	NOUN
bjp-81605	168	3	to	to	ADP
bjp-81605	168	4	the	the	DET
bjp-81605	168	5	control	control	NOUN
bjp-81605	168	6	group	group	NOUN
bjp-81605	168	7	,	,	PUNCT
bjp-81605	168	8	where	where	SCONJ
bjp-81605	168	9	crt2	crt2	PROPN
bjp-81605	168	10	-	-	PUNCT
bjp-81605	168	11	induced	induce	VERB
bjp-81605	168	12	membrane	membrane	NOUN
bjp-81605	168	13	depolarization	depolarization	NOUN
bjp-81605	168	14	resulted	result	VERB
bjp-81605	168	15	in	in	ADP
bjp-81605	168	16	loss	loss	NOUN
bjp-81605	168	17	of	of	ADP
bjp-81605	168	18	mitochondrial	mitochondrial	ADJ
bjp-81605	168	19	integrity	integrity	NOUN
bjp-81605	168	20	,	,	PUNCT
bjp-81605	168	21	crt2	crt2	PROPN
bjp-81605	168	22	therapy	therapy	NOUN
bjp-81605	168	23	enhanced	enhance	VERB
bjp-81605	168	24	the	the	DET
bjp-81605	168	25	accumulation	accumulation	NOUN
bjp-81605	168	26	of	of	ADP
bjp-81605	168	27	jc-1	jc-1	NOUN
bjp-81605	168	28	monomer	monomer	NOUN
bjp-81605	168	29	in	in	ADP
bjp-81605	168	30	cells	cell	NOUN
bjp-81605	168	31	.	.	PUNCT
bjp-81605	169	1	the	the	DET
bjp-81605	169	2	image	image	NOUN
bjp-81605	169	3	clearly	clearly	ADV
bjp-81605	169	4	illustrates	illustrate	VERB
bjp-81605	169	5	the	the	DET
bjp-81605	169	6	ratio	ratio	NOUN
bjp-81605	169	7	of	of	ADP
bjp-81605	169	8	red	red	ADJ
bjp-81605	169	9	to	to	ADP
bjp-81605	169	10	green	green	ADJ
bjp-81605	169	11	fluorescence	fluorescence	NOUN
bjp-81605	169	12	intensity	intensity	NOUN
bjp-81605	169	13	,	,	PUNCT
bjp-81605	169	14	cell	cell	NOUN
bjp-81605	169	15	death	death	NOUN
bjp-81605	169	16	,	,	PUNCT
bjp-81605	169	17	or	or	CCONJ
bjp-81605	169	18	damage	damage	NOUN
bjp-81605	169	19	in	in	ADP
bjp-81605	169	20	comparison	comparison	NOUN
bjp-81605	169	21	to	to	PART
bjp-81605	169	22	control	control	VERB
bjp-81605	169	23	clustered	clustered	ADJ
bjp-81605	169	24	cells	cell	NOUN
bjp-81605	169	25	.	.	PUNCT
bjp-81605	170	1	when	when	SCONJ
bjp-81605	170	2	compared	compare	VERB
bjp-81605	170	3	figure	figure	NOUN
bjp-81605	170	4	3	3	NUM
bjp-81605	170	5	:	:	PUNCT
bjp-81605	170	6	ht-116	ht-116	PROPN
bjp-81605	170	7	cells	cell	NOUN
bjp-81605	170	8	were	be	AUX
bjp-81605	170	9	coupled	couple	VERB
bjp-81605	170	10	with	with	ADP
bjp-81605	170	11	either	either	CCONJ
bjp-81605	170	12	fitc	fitc	PROPN
bjp-81605	170	13	-	-	PUNCT
bjp-81605	170	14	scr	scr	NOUN
bjp-81605	170	15	peptide	peptide	NOUN
bjp-81605	170	16	(	(	PUNCT
bjp-81605	170	17	0.60	0.60	NUM
bjp-81605	170	18	μm	μm	NOUN
bjp-81605	170	19	)	)	PUNCT
bjp-81605	170	20	or	or	CCONJ
bjp-81605	170	21	fitc	fitc	NOUN
bjp-81605	170	22	-	-	PUNCT
bjp-81605	170	23	crt2	crt2	PROPN
bjp-81605	170	24	peptide	peptide	NOUN
bjp-81605	170	25	(	(	PUNCT
bjp-81605	170	26	0.35	0.35	NUM
bjp-81605	170	27	and	and	CCONJ
bjp-81605	170	28	0.75	0.75	NUM
bjp-81605	170	29	μm	μm	NUM
bjp-81605	170	30	)	)	PUNCT
bjp-81605	170	31	for	for	ADP
bjp-81605	170	32	a	a	DET
bjp-81605	170	33	predefined	predefine	VERB
bjp-81605	170	34	amount	amount	NOUN
bjp-81605	170	35	of	of	ADP
bjp-81605	170	36	time	time	NOUN
bjp-81605	170	37	(	(	PUNCT
bjp-81605	170	38	green	green	ADJ
bjp-81605	170	39	curve	curve	NOUN
bjp-81605	170	40	)	)	PUNCT
bjp-81605	170	41	.	.	PUNCT
bjp-81605	171	1	the	the	DET
bjp-81605	171	2	auto	auto	NOUN
bjp-81605	171	3	fluorescence	fluorescence	NOUN
bjp-81605	171	4	of	of	ADP
bjp-81605	171	5	the	the	DET
bjp-81605	171	6	cells	cell	NOUN
bjp-81605	171	7	is	be	AUX
bjp-81605	171	8	represented	represent	VERB
bjp-81605	171	9	by	by	ADP
bjp-81605	171	10	a	a	DET
bjp-81605	171	11	pink	pink	ADJ
bjp-81605	171	12	curve	curve	NOUN
bjp-81605	171	13	(	(	PUNCT
bjp-81605	171	14	a	a	NOUN
bjp-81605	171	15	)	)	PUNCT
bjp-81605	171	16	.	.	PUNCT
bjp-81605	172	1	ht-116	ht-116	PROPN
bjp-81605	172	2	was	be	AUX
bjp-81605	172	3	exposed	expose	VERB
bjp-81605	172	4	to	to	ADP
bjp-81605	172	5	different	different	ADJ
bjp-81605	172	6	concentrations	concentration	NOUN
bjp-81605	172	7	of	of	ADP
bjp-81605	172	8	scr	scr	NOUN
bjp-81605	172	9	peptide	peptide	NOUN
bjp-81605	172	10	(	(	PUNCT
bjp-81605	172	11	0.60	0.60	NUM
bjp-81605	172	12	μm	μm	NOUN
bjp-81605	172	13	)	)	PUNCT
bjp-81605	172	14	or	or	CCONJ
bjp-81605	172	15	crt2	crt2	PROPN
bjp-81605	172	16	peptide	peptide	NOUN
bjp-81605	172	17	(	(	PUNCT
bjp-81605	172	18	0.35	0.35	NUM
bjp-81605	172	19	and	and	CCONJ
bjp-81605	172	20	0.75	0.75	NUM
bjp-81605	172	21	μm	μm	NUM
bjp-81605	172	22	)	)	PUNCT
bjp-81605	172	23	for	for	ADP
bjp-81605	172	24	an	an	DET
bjp-81605	172	25	entire	entire	ADJ
bjp-81605	172	26	night	night	NOUN
bjp-81605	172	27	in	in	ADP
bjp-81605	172	28	the	the	DET
bjp-81605	172	29	dark	dark	ADJ
bjp-81605	172	30	(	(	PUNCT
bjp-81605	172	31	green	green	ADJ
bjp-81605	172	32	curve	curve	NOUN
bjp-81605	172	33	)	)	PUNCT
bjp-81605	172	34	(	(	PUNCT
bjp-81605	172	35	b	b	X
bjp-81605	172	36	)	)	PUNCT
bjp-81605	172	37	b	b	NOUN
bjp-81605	172	38	a	a	DET
bjp-81605	172	39	94	94	NUM
bjp-81605	172	40	bangladesh	bangladesh	NOUN
bjp-81605	172	41	j	j	PROPN
bjp-81605	172	42	pharmacol	pharmacol	PROPN
bjp-81605	172	43	2025	2025	NUM
bjp-81605	172	44	;	;	PUNCT
bjp-81605	172	45	20	20	NUM
bjp-81605	172	46	:	:	SYM
bjp-81605	172	47	89	89	NUM
bjp-81605	172	48	-	-	SYM
bjp-81605	172	49	100	100	NUM
bjp-81605	172	50	to	to	ADP
bjp-81605	172	51	control	control	NOUN
bjp-81605	172	52	cells	cell	NOUN
bjp-81605	172	53	,	,	PUNCT
bjp-81605	172	54	crt2	crt2	PROPN
bjp-81605	172	55	at	at	ADP
bjp-81605	172	56	0	0	NUM
bjp-81605	172	57	,	,	PUNCT
bjp-81605	172	58	10	10	NUM
bjp-81605	172	59	,	,	PUNCT
bjp-81605	172	60	and	and	CCONJ
bjp-81605	172	61	20	20	NUM
bjp-81605	172	62	µm	µm	NOUN
bjp-81605	172	63	displayed	display	VERB
bjp-81605	172	64	a	a	DET
bjp-81605	172	65	1.3	1.3	NUM
bjp-81605	172	66	-fold	-fold	ADJ
bjp-81605	172	67	drop	drop	NOUN
bjp-81605	172	68	in	in	ADP
bjp-81605	172	69	mitochondrial	mitochondrial	ADJ
bjp-81605	172	70	membrane	membrane	NOUN
bjp-81605	172	71	potential	potential	NOUN
bjp-81605	172	72	.	.	PUNCT
bjp-81605	173	1	colony	colony	NOUN
bjp-81605	173	2	formation	formation	NOUN
bjp-81605	173	3	of	of	ADP
bjp-81605	173	4	spheroid	spheroid	NOUN
bjp-81605	173	5	ht-116	ht-116	VERB
bjp-81605	173	6	cancer	cancer	NOUN
bjp-81605	173	7	cell	cell	NOUN
bjp-81605	173	8	lines	line	NOUN
bjp-81605	173	9	in	in	ADP
bjp-81605	173	10	ht-116	ht-116	PROPN
bjp-81605	173	11	cells	cell	NOUN
bjp-81605	173	12	,	,	PUNCT
bjp-81605	173	13	crt2	crt2	PROPN
bjp-81605	173	14	significantly	significantly	ADV
bjp-81605	173	15	reduced	reduce	VERB
bjp-81605	173	16	colony	colony	NOUN
bjp-81605	173	17	formation	formation	NOUN
bjp-81605	173	18	as	as	SCONJ
bjp-81605	173	19	compared	compare	VERB
bjp-81605	173	20	to	to	ADP
bjp-81605	173	21	the	the	DET
bjp-81605	173	22	vehicle	vehicle	NOUN
bjp-81605	173	23	(	(	PUNCT
bjp-81605	173	24	dmso	dmso	NOUN
bjp-81605	173	25	)	)	PUNCT
bjp-81605	173	26	group	group	NOUN
bjp-81605	173	27	.	.	PUNCT
bjp-81605	174	1	phase	phase	NOUN
bjp-81605	174	2	contrast	contrast	NOUN
bjp-81605	174	3	microscopy	microscopy	NOUN
bjp-81605	174	4	was	be	AUX
bjp-81605	174	5	used	use	VERB
bjp-81605	174	6	to	to	PART
bjp-81605	174	7	show	show	VERB
bjp-81605	174	8	the	the	DET
bjp-81605	174	9	colony	colony	NOUN
bjp-81605	174	10	population	population	NOUN
bjp-81605	174	11	density	density	NOUN
bjp-81605	174	12	in	in	ADP
bjp-81605	174	13	each	each	DET
bjp-81605	174	14	plate	plate	NOUN
bjp-81605	174	15	after	after	ADP
bjp-81605	174	16	treatment	treatment	NOUN
bjp-81605	174	17	(	(	PUNCT
bjp-81605	174	18	figure	figure	VERB
bjp-81605	174	19	6a	6a	NOUN
bjp-81605	174	20	)	)	PUNCT
bjp-81605	174	21	.	.	PUNCT
bjp-81605	175	1	density	density	NOUN
bjp-81605	175	2	measurements	measurement	NOUN
bjp-81605	175	3	compared	compare	VERB
bjp-81605	175	4	the	the	DET
bjp-81605	175	5	control	control	NOUN
bjp-81605	175	6	and	and	CCONJ
bjp-81605	175	7	treatment	treatment	NOUN
bjp-81605	175	8	groups	group	NOUN
bjp-81605	175	9	.	.	PUNCT
bjp-81605	176	1	colony	colony	NOUN
bjp-81605	176	2	development	development	NOUN
bjp-81605	176	3	was	be	AUX
bjp-81605	176	4	reduced	reduce	VERB
bjp-81605	176	5	by	by	ADP
bjp-81605	176	6	more	more	ADJ
bjp-81605	176	7	than	than	ADP
bjp-81605	176	8	50	50	NUM
bjp-81605	176	9	%	%	NOUN
bjp-81605	176	10	when	when	SCONJ
bjp-81605	176	11	the	the	DET
bjp-81605	176	12	crt2	crt2	PROPN
bjp-81605	176	13	peptide	peptide	NOUN
bjp-81605	176	14	was	be	AUX
bjp-81605	176	15	administered	administer	VERB
bjp-81605	176	16	at	at	ADP
bjp-81605	176	17	0	0	NUM
bjp-81605	176	18	,	,	PUNCT
bjp-81605	176	19	10	10	NUM
bjp-81605	176	20	,	,	PUNCT
bjp-81605	176	21	and	and	CCONJ
bjp-81605	176	22	20	20	NUM
bjp-81605	176	23	µm	µm	NOUN
bjp-81605	176	24	,	,	PUNCT
bjp-81605	176	25	or	or	CCONJ
bjp-81605	176	26	about	about	ADP
bjp-81605	176	27	half	half	DET
bjp-81605	176	28	the	the	DET
bjp-81605	176	29	ic50	ic50	PROPN
bjp-81605	176	30	dose	dose	NOUN
bjp-81605	176	31	.	.	PUNCT
bjp-81605	177	1	moreover	moreover	ADV
bjp-81605	177	2	,	,	PUNCT
bjp-81605	177	3	the	the	DET
bjp-81605	177	4	ht-116	ht-116	PROPN
bjp-81605	177	5	cell	cell	NOUN
bjp-81605	177	6	line	line	NOUN
bjp-81605	177	7	had	have	VERB
bjp-81605	177	8	anti	anti	ADJ
bjp-81605	177	9	-	-	ADJ
bjp-81605	177	10	angiogenic	angiogenic	ADJ
bjp-81605	177	11	properties	property	NOUN
bjp-81605	177	12	.	.	PUNCT
bjp-81605	178	1	using	use	VERB
bjp-81605	178	2	the	the	DET
bjp-81605	178	3	matrigel	matrigel	NOUN
bjp-81605	178	4	invasion	invasion	NOUN
bjp-81605	178	5	assay	assay	VERB
bjp-81605	178	6	,	,	PUNCT
bjp-81605	178	7	the	the	DET
bjp-81605	178	8	crt2	crt2	PROPN
bjp-81605	178	9	therapy	therapy	NOUN
bjp-81605	178	10	of	of	ADP
bjp-81605	178	11	ht-116	ht-116	PROPN
bjp-81605	178	12	cells	cell	NOUN
bjp-81605	178	13	was	be	AUX
bjp-81605	178	14	evaluated	evaluate	VERB
bjp-81605	178	15	.	.	PUNCT
bjp-81605	179	1	crt2	crt2	PROPN
bjp-81605	179	2	dramatically	dramatically	ADV
bjp-81605	179	3	decreases	decrease	VERB
bjp-81605	179	4	the	the	DET
bjp-81605	179	5	invasive	invasive	ADJ
bjp-81605	179	6	capacity	capacity	NOUN
bjp-81605	179	7	of	of	ADP
bjp-81605	179	8	ht-116	ht-116	PROPN
bjp-81605	179	9	cells	cell	NOUN
bjp-81605	179	10	in	in	ADP
bjp-81605	179	11	a	a	DET
bjp-81605	179	12	concentrationor	concentrationor	NOUN
bjp-81605	179	13	dose	dose	NOUN
bjp-81605	179	14	-	-	PUNCT
bjp-81605	179	15	dependent	dependent	ADJ
bjp-81605	179	16	manner	manner	NOUN
bjp-81605	179	17	(	(	PUNCT
bjp-81605	179	18	figure	figure	NOUN
bjp-81605	179	19	6b	6b	NUM
bjp-81605	179	20	)	)	PUNCT
bjp-81605	179	21	.	.	PUNCT
bjp-81605	180	1	apoptosis	apoptosis	NOUN
bjp-81605	180	2	via	via	ADP
bjp-81605	180	3	the	the	DET
bjp-81605	180	4	mitochondrial	mitochondrial	ADJ
bjp-81605	180	5	pathway	pathway	NOUN
bjp-81605	180	6	the	the	DET
bjp-81605	180	7	apoptotic	apoptotic	ADJ
bjp-81605	180	8	potential	potential	NOUN
bjp-81605	180	9	of	of	ADP
bjp-81605	180	10	crt2	crt2	PROPN
bjp-81605	180	11	in	in	ADP
bjp-81605	180	12	ht-116	ht-116	PROPN
bjp-81605	180	13	cells	cell	NOUN
bjp-81605	180	14	was	be	AUX
bjp-81605	180	15	assessed	assess	VERB
bjp-81605	180	16	using	use	VERB
bjp-81605	180	17	propidium	propidium	NOUN
bjp-81605	180	18	iodide	iodide	NOUN
bjp-81605	180	19	and	and	CCONJ
bjp-81605	180	20	annexin	annexin	NOUN
bjp-81605	180	21	v	v	NOUN
bjp-81605	180	22	-	-	PUNCT
bjp-81605	180	23	fitc	fitc	NOUN
bjp-81605	180	24	dual	dual	ADJ
bjp-81605	180	25	labeling	labeling	NOUN
bjp-81605	180	26	in	in	ADP
bjp-81605	180	27	a	a	DET
bjp-81605	180	28	flow	flow	NOUN
bjp-81605	180	29	cytometry	cytometry	NOUN
bjp-81605	180	30	study	study	NOUN
bjp-81605	180	31	(	(	PUNCT
bjp-81605	180	32	figure	figure	NOUN
bjp-81605	180	33	7a	7a	NUM
bjp-81605	180	34	)	)	PUNCT
bjp-81605	180	35	.	.	PUNCT
bjp-81605	181	1	after	after	ADP
bjp-81605	181	2	being	be	AUX
bjp-81605	181	3	exposed	expose	VERB
bjp-81605	181	4	to	to	ADP
bjp-81605	181	5	their	their	PRON
bjp-81605	181	6	respective	respective	ADJ
bjp-81605	181	7	ic50	ic50	PROPN
bjp-81605	181	8	values	value	NOUN
bjp-81605	181	9	,	,	PUNCT
bjp-81605	181	10	the	the	DET
bjp-81605	181	11	ht-116	ht-116	PROPN
bjp-81605	181	12	cell	cell	NOUN
bjp-81605	181	13	lines	line	NOUN
bjp-81605	181	14	increased	increase	VERB
bjp-81605	181	15	the	the	DET
bjp-81605	181	16	fraction	fraction	NOUN
bjp-81605	181	17	of	of	ADP
bjp-81605	181	18	late	late	ADJ
bjp-81605	181	19	-	-	PUNCT
bjp-81605	181	20	apoptotic	apoptotic	ADJ
bjp-81605	181	21	cells	cell	NOUN
bjp-81605	181	22	,	,	PUNCT
bjp-81605	181	23	a	a	DET
bjp-81605	181	24	total	total	ADJ
bjp-81605	181	25	apoptosis	apoptosis	NOUN
bjp-81605	181	26	rate	rate	NOUN
bjp-81605	181	27	of	of	ADP
bjp-81605	181	28	87.3	87.3	NUM
bjp-81605	181	29	%	%	NOUN
bjp-81605	181	30	(	(	PUNCT
bjp-81605	181	31	figure	figure	NOUN
bjp-81605	181	32	7b	7b	NUM
bjp-81605	181	33	)	)	PUNCT
bjp-81605	181	34	.	.	PUNCT
bjp-81605	182	1	notably	notably	ADV
bjp-81605	182	2	,	,	PUNCT
bjp-81605	182	3	the	the	DET
bjp-81605	182	4	number	number	NOUN
bjp-81605	182	5	of	of	ADP
bjp-81605	182	6	late	late	ADJ
bjp-81605	182	7	apoptotic	apoptotic	ADJ
bjp-81605	182	8	cells	cell	NOUN
bjp-81605	182	9	increased	increase	VERB
bjp-81605	182	10	significantly	significantly	ADV
bjp-81605	182	11	.	.	PUNCT
bjp-81605	183	1	the	the	DET
bjp-81605	183	2	level	level	NOUN
bjp-81605	183	3	of	of	ADP
bjp-81605	183	4	proand	proand	NOUN
bjp-81605	183	5	anti	anti	ADJ
bjp-81605	183	6	-	-	ADJ
bjp-81605	183	7	apoptotic	apoptotic	ADJ
bjp-81605	183	8	proteins	protein	NOUN
bjp-81605	183	9	was	be	AUX
bjp-81605	183	10	assessed	assess	VERB
bjp-81605	183	11	in	in	ADP
bjp-81605	183	12	both	both	DET
bjp-81605	183	13	cancer	cancer	NOUN
bjp-81605	183	14	cell	cell	NOUN
bjp-81605	183	15	lines	line	NOUN
bjp-81605	183	16	.	.	PUNCT
bjp-81605	184	1	crt2	crt2	PROPN
bjp-81605	184	2	resulted	result	VERB
bjp-81605	184	3	in	in	ADP
bjp-81605	184	4	a	a	DET
bjp-81605	184	5	dose	dose	NOUN
bjp-81605	184	6	-	-	PUNCT
bjp-81605	184	7	dependent	dependent	ADJ
bjp-81605	184	8	reduction	reduction	NOUN
bjp-81605	184	9	in	in	ADP
bjp-81605	184	10	the	the	DET
bjp-81605	184	11	levels	level	NOUN
bjp-81605	184	12	of	of	ADP
bjp-81605	184	13	antiapoptotic	antiapoptotic	NOUN
bjp-81605	184	14	bcl-2	bcl-2	NOUN
bjp-81605	184	15	despite	despite	SCONJ
bjp-81605	184	16	a	a	DET
bjp-81605	184	17	considerable	considerable	ADJ
bjp-81605	184	18	increase	increase	NOUN
bjp-81605	184	19	in	in	ADP
bjp-81605	184	20	the	the	DET
bjp-81605	184	21	bax	bax	NOUN
bjp-81605	184	22	protein	protein	NOUN
bjp-81605	184	23	level	level	NOUN
bjp-81605	184	24	(	(	PUNCT
bjp-81605	184	25	figure	figure	NOUN
bjp-81605	184	26	7c	7c	NUM
bjp-81605	184	27	)	)	PUNCT
bjp-81605	184	28	.	.	PUNCT
bjp-81605	185	1	cell	cell	NOUN
bjp-81605	185	2	cycle	cycle	NOUN
bjp-81605	185	3	in	in	ADP
bjp-81605	185	4	colorectal	colorectal	ADJ
bjp-81605	185	5	cancer	cancer	NOUN
bjp-81605	185	6	cell	cell	NOUN
bjp-81605	185	7	lines	line	NOUN
bjp-81605	185	8	to	to	PART
bjp-81605	185	9	ascertain	ascertain	VERB
bjp-81605	185	10	whether	whether	SCONJ
bjp-81605	185	11	a	a	DET
bjp-81605	185	12	particular	particular	ADJ
bjp-81605	185	13	cell	cell	NOUN
bjp-81605	185	14	cycle	cycle	NOUN
bjp-81605	185	15	arrest	arrest	NOUN
bjp-81605	185	16	mediated	mediate	VERB
bjp-81605	185	17	by	by	ADP
bjp-81605	185	18	the	the	DET
bjp-81605	185	19	antiproliferative	antiproliferative	ADJ
bjp-81605	185	20	impact	impact	NOUN
bjp-81605	185	21	of	of	ADP
bjp-81605	185	22	crt2	crt2	PROPN
bjp-81605	185	23	on	on	ADP
bjp-81605	185	24	ht-116	ht-116	PROPN
bjp-81605	185	25	cell	cell	NOUN
bjp-81605	185	26	lines	line	NOUN
bjp-81605	185	27	,	,	PUNCT
bjp-81605	185	28	we	we	PRON
bjp-81605	185	29	examined	examine	VERB
bjp-81605	185	30	the	the	DET
bjp-81605	185	31	cell	cell	NOUN
bjp-81605	185	32	cycle	cycle	NOUN
bjp-81605	185	33	phase	phase	NOUN
bjp-81605	185	34	distribution	distribution	NOUN
bjp-81605	185	35	after	after	ADP
bjp-81605	185	36	crt2	crt2	PROPN
bjp-81605	185	37	treatment	treatment	NOUN
bjp-81605	185	38	(	(	PUNCT
bjp-81605	185	39	figure	figure	NOUN
bjp-81605	185	40	8a	8a	NUM
bjp-81605	185	41	)	)	PUNCT
bjp-81605	185	42	.	.	PUNCT
bjp-81605	186	1	crt2	crt2	PROPN
bjp-81605	186	2	cells	cell	NOUN
bjp-81605	186	3	treated	treat	VERB
bjp-81605	186	4	with	with	ADP
bjp-81605	186	5	0	0	NUM
bjp-81605	186	6	,	,	PUNCT
bjp-81605	186	7	10	10	NUM
bjp-81605	186	8	,	,	PUNCT
bjp-81605	186	9	and	and	CCONJ
bjp-81605	186	10	20	20	NUM
bjp-81605	186	11	µm	µm	NOUN
bjp-81605	186	12	for	for	ADP
bjp-81605	186	13	24	24	NUM
bjp-81605	186	14	hours	hour	NOUN
bjp-81605	186	15	demonstrated	demonstrate	VERB
bjp-81605	186	16	a	a	DET
bjp-81605	186	17	clear	clear	ADJ
bjp-81605	186	18	cell	cell	NOUN
bjp-81605	186	19	accumulation	accumulation	NOUN
bjp-81605	186	20	during	during	ADP
bjp-81605	186	21	the	the	DET
bjp-81605	186	22	g1	g1	PROPN
bjp-81605	186	23	/	/	SYM
bjp-81605	186	24	s	s	PART
bjp-81605	186	25	phase	phase	NOUN
bjp-81605	186	26	(	(	PUNCT
bjp-81605	186	27	figure	figure	NOUN
bjp-81605	186	28	8b	8b	NUM
bjp-81605	186	29	)	)	PUNCT
bjp-81605	186	30	.	.	PUNCT
bjp-81605	187	1	g1	g1	PROPN
bjp-81605	187	2	/	/	SYM
bjp-81605	187	3	s	s	PART
bjp-81605	187	4	phase	phase	NOUN
bjp-81605	187	5	arrest	arrest	NOUN
bjp-81605	187	6	was	be	AUX
bjp-81605	187	7	further	far	ADV
bjp-81605	187	8	confirmed	confirm	VERB
bjp-81605	187	9	by	by	ADP
bjp-81605	187	10	expression	expression	NOUN
bjp-81605	187	11	of	of	ADP
bjp-81605	187	12	cdk	cdk	PROPN
bjp-81605	187	13	,	,	PUNCT
bjp-81605	187	14	ckis	cki	NOUN
bjp-81605	187	15	,	,	PUNCT
bjp-81605	187	16	and	and	CCONJ
bjp-81605	187	17	cyclins	cyclin	NOUN
bjp-81605	187	18	.	.	PUNCT
bjp-81605	188	1	in	in	ADP
bjp-81605	188	2	ht-116	ht-116	PROPN
bjp-81605	188	3	cells	cell	NOUN
bjp-81605	188	4	,	,	PUNCT
bjp-81605	188	5	crt2	crt2	PROPN
bjp-81605	188	6	significantly	significantly	ADV
bjp-81605	188	7	reduced	reduce	VERB
bjp-81605	188	8	the	the	DET
bjp-81605	188	9	amount	amount	NOUN
bjp-81605	188	10	of	of	ADP
bjp-81605	188	11	cyclin	cyclin	NOUN
bjp-81605	188	12	d1	d1	PROPN
bjp-81605	188	13	and	and	CCONJ
bjp-81605	188	14	elevated	elevate	VERB
bjp-81605	188	15	the	the	DET
bjp-81605	188	16	expression	expression	NOUN
bjp-81605	188	17	of	of	ADP
bjp-81605	188	18	the	the	DET
bjp-81605	188	19	cell	cell	NOUN
bjp-81605	188	20	cycle	cycle	NOUN
bjp-81605	188	21	inhibitory	inhibitory	ADJ
bjp-81605	188	22	protein	protein	NOUN
bjp-81605	188	23	p21	p21	NOUN
bjp-81605	188	24	(	(	PUNCT
bjp-81605	188	25	figure	figure	NOUN
bjp-81605	188	26	8c	8c	NUM
bjp-81605	188	27	)	)	PUNCT
bjp-81605	188	28	.	.	PUNCT
bjp-81605	189	1	the	the	DET
bjp-81605	189	2	peptide	peptide	NOUN
bjp-81605	189	3	inhibits	inhibit	VERB
bjp-81605	189	4	cell	cell	NOUN
bjp-81605	189	5	development	development	NOUN
bjp-81605	189	6	in	in	ADP
bjp-81605	189	7	ht-116	ht-116	PROPN
bjp-81605	189	8	cancer	cancer	NOUN
bjp-81605	189	9	cells	cell	NOUN
bjp-81605	189	10	by	by	ADP
bjp-81605	189	11	blocking	block	VERB
bjp-81605	189	12	the	the	DET
bjp-81605	189	13	cell	cell	NOUN
bjp-81605	189	14	cycle	cycle	NOUN
bjp-81605	189	15	transition	transition	NOUN
bjp-81605	189	16	from	from	ADP
bjp-81605	189	17	g1	g1	PROPN
bjp-81605	189	18	to	to	ADP
bjp-81605	189	19	s	s	PRON
bjp-81605	189	20	,	,	PUNCT
bjp-81605	189	21	as	as	ADP
bjp-81605	189	22	observed	observed	ADJ
bjp-81605	189	23	g1	g1	NOUN
bjp-81605	189	24	/	/	SYM
bjp-81605	189	25	s	s	PART
bjp-81605	189	26	phase	phase	NOUN
bjp-81605	189	27	arrest	arrest	NOUN
bjp-81605	189	28	with	with	ADP
bjp-81605	189	29	crt2	crt2	PROPN
bjp-81605	189	30	treatment	treatment	NOUN
bjp-81605	189	31	.	.	PUNCT
bjp-81605	190	1	constitutive	constitutive	ADJ
bjp-81605	190	2	and	and	CCONJ
bjp-81605	190	3	vegfa	vegfa	ADV
bjp-81605	190	4	-	-	PUNCT
bjp-81605	190	5	induced	induce	VERB
bjp-81605	190	6	phosphorylation	phosphorylation	NOUN
bjp-81605	190	7	of	of	ADP
bjp-81605	190	8	vegfr1	vegfr1	NOUN
bjp-81605	190	9	like	like	ADP
bjp-81605	190	10	vegf	vegf	PROPN
bjp-81605	190	11	overexpression	overexpression	NOUN
bjp-81605	190	12	,	,	PUNCT
bjp-81605	190	13	incorrect	incorrect	ADJ
bjp-81605	190	14	vegfr1	vegfr1	NOUN
bjp-81605	190	15	activation	activation	NOUN
bjp-81605	190	16	had	have	AUX
bjp-81605	190	17	been	be	AUX
bjp-81605	190	18	reported	report	VERB
bjp-81605	190	19	in	in	ADP
bjp-81605	190	20	cancer	cancer	NOUN
bjp-81605	190	21	cells	cell	NOUN
bjp-81605	190	22	,	,	PUNCT
bjp-81605	190	23	including	include	VERB
bjp-81605	190	24	colorectal	colorectal	ADJ
bjp-81605	190	25	cancer	cancer	NOUN
bjp-81605	190	26	cell	cell	NOUN
bjp-81605	190	27	lines	line	NOUN
bjp-81605	190	28	.	.	PUNCT
bjp-81605	191	1	dysregulation	dysregulation	NOUN
bjp-81605	191	2	of	of	ADP
bjp-81605	191	3	downstream	downstream	ADJ
bjp-81605	191	4	signaling	signal	VERB
bjp-81605	191	5	is	be	AUX
bjp-81605	191	6	the	the	DET
bjp-81605	191	7	outcome	outcome	NOUN
bjp-81605	191	8	of	of	ADP
bjp-81605	191	9	vegfr1	vegfr1	NOUN
bjp-81605	191	10	dimerization	dimerization	NOUN
bjp-81605	191	11	,	,	PUNCT
bjp-81605	191	12	which	which	PRON
bjp-81605	191	13	is	be	AUX
bjp-81605	191	14	triggered	trigger	VERB
bjp-81605	191	15	by	by	ADP
bjp-81605	191	16	phosphorylation	phosphorylation	NOUN
bjp-81605	191	17	that	that	PRON
bjp-81605	191	18	is	be	AUX
bjp-81605	191	19	dependent	dependent	ADJ
bjp-81605	191	20	on	on	ADP
bjp-81605	191	21	the	the	DET
bjp-81605	191	22	vegfa	vegfa	PROPN
bjp-81605	191	23	ligand	ligand	NOUN
bjp-81605	191	24	.	.	PUNCT
bjp-81605	192	1	this	this	DET
bjp-81605	192	2	study	study	NOUN
bjp-81605	192	3	investigated	investigate	VERB
bjp-81605	192	4	the	the	DET
bjp-81605	192	5	effects	effect	NOUN
bjp-81605	192	6	of	of	ADP
bjp-81605	192	7	crt2	crt2	PROPN
bjp-81605	192	8	in	in	ADP
bjp-81605	192	9	control	control	NOUN
bjp-81605	192	10	groups	group	NOUN
bjp-81605	192	11	,	,	PUNCT
bjp-81605	192	12	10	10	NUM
bjp-81605	192	13	-	-	SYM
bjp-81605	192	14	20	20	NUM
bjp-81605	192	15	µm	µm	NOUN
bjp-81605	192	16	over	over	ADP
bjp-81605	192	17	24	24	NUM
bjp-81605	192	18	hours	hour	NOUN
bjp-81605	192	19	on	on	ADP
bjp-81605	192	20	the	the	DET
bjp-81605	192	21	vegfr1	vegfr1	NOUN
bjp-81605	192	22	-	-	PUNCT
bjp-81605	192	23	positive	positive	ADJ
bjp-81605	192	24	colorectal	colorectal	ADJ
bjp-81605	192	25	cancer	cancer	NOUN
bjp-81605	192	26	cells	cell	NOUN
bjp-81605	192	27	.	.	PUNCT
bjp-81605	193	1	figure	figure	VERB
bjp-81605	193	2	4	4	NUM
bjp-81605	193	3	:	:	PUNCT
bjp-81605	193	4	effects	effect	NOUN
bjp-81605	193	5	of	of	ADP
bjp-81605	193	6	crt2	crt2	PROPN
bjp-81605	193	7	peptide	peptide	NOUN
bjp-81605	193	8	cytotoxicity	cytotoxicity	NOUN
bjp-81605	193	9	on	on	ADP
bjp-81605	193	10	ht-116	ht-116	PROPN
bjp-81605	193	11	cancer	cancer	NOUN
bjp-81605	193	12	cells	cell	NOUN
bjp-81605	193	13	treated	treat	VERB
bjp-81605	193	14	for	for	ADP
bjp-81605	193	15	24	24	NUM
bjp-81605	193	16	to	to	PART
bjp-81605	193	17	48	48	NUM
bjp-81605	193	18	hours	hour	NOUN
bjp-81605	193	19	(	(	PUNCT
bjp-81605	193	20	a	a	PRON
bjp-81605	193	21	and	and	CCONJ
bjp-81605	193	22	b	b	NOUN
bjp-81605	193	23	)	)	PUNCT
bjp-81605	193	24	.	.	PUNCT
bjp-81605	194	1	morphological	morphological	ADJ
bjp-81605	194	2	analyses	analysis	NOUN
bjp-81605	194	3	employing	employ	VERB
bjp-81605	194	4	ht-116	ht-116	PROPN
bjp-81605	194	5	cell	cell	NOUN
bjp-81605	194	6	lines	line	NOUN
bjp-81605	194	7	treated	treat	VERB
bjp-81605	194	8	with	with	ADP
bjp-81605	194	9	crt2	crt2	PROPN
bjp-81605	194	10	peptide	peptide	NOUN
bjp-81605	194	11	to	to	PART
bjp-81605	194	12	distinguish	distinguish	VERB
bjp-81605	194	13	between	between	ADP
bjp-81605	194	14	living	live	VERB
bjp-81605	194	15	,	,	PUNCT
bjp-81605	194	16	apoptotic	apoptotic	ADJ
bjp-81605	194	17	,	,	PUNCT
bjp-81605	194	18	and	and	CCONJ
bjp-81605	194	19	necrotic	necrotic	ADJ
bjp-81605	194	20	cells	cell	NOUN
bjp-81605	194	21	using	use	VERB
bjp-81605	194	22	the	the	DET
bjp-81605	194	23	ao/	ao/	ADJ
bjp-81605	194	24	eb	eb	NOUN
bjp-81605	194	25	staining	stain	VERB
bjp-81605	194	26	techniques	technique	NOUN
bjp-81605	194	27	green	green	ADJ
bjp-81605	194	28	and	and	CCONJ
bjp-81605	194	29	red	red	ADJ
bjp-81605	194	30	fluorescence	fluorescence	NOUN
bjp-81605	194	31	(	(	PUNCT
bjp-81605	194	32	c	c	NOUN
bjp-81605	194	33	)	)	PUNCT
bjp-81605	194	34	.	.	PUNCT
bjp-81605	195	1	data	datum	NOUN
bjp-81605	195	2	were	be	AUX
bjp-81605	195	3	mean	mean	PROPN
bjp-81605	195	4	±	±	NUM
bjp-81605	195	5	sd	sd	NOUN
bjp-81605	195	6	;	;	PUNCT
bjp-81605	195	7	n=3	n=3	VERB
bjp-81605	195	8	.	.	NOUN
bjp-81605	196	1	in	in	ADP
bjp-81605	196	2	relation	relation	NOUN
bjp-81605	196	3	to	to	ADP
bjp-81605	196	4	the	the	DET
bjp-81605	196	5	control	control	NOUN
bjp-81605	196	6	,	,	PUNCT
bjp-81605	196	7	ap<0.001	ap<0.001	PROPN
bjp-81605	196	8	c	c	NOUN
bjp-81605	196	9	a	a	DET
bjp-81605	196	10	b	b	PROPN
bjp-81605	196	11	control	control	VERB
bjp-81605	196	12	-	-	PUNCT
bjp-81605	196	13	vegfa	vegfa	PROPN
bjp-81605	196	14	scr	scr	NOUN
bjp-81605	196	15	60	60	NUM
bjp-81605	196	16	µm	µm	ADP
bjp-81605	196	17	crt2	crt2	PROPN
bjp-81605	196	18	6.25	6.25	NUM
bjp-81605	196	19	µm	µm	ADP
bjp-81605	196	20	crt2	crt2	PROPN
bjp-81605	196	21	12.5	12.5	NUM
bjp-81605	196	22	µm	µm	ADP
bjp-81605	196	23	crt2	crt2	PROPN
bjp-81605	196	24	25	25	NUM
bjp-81605	196	25	µm	µm	ADP
bjp-81605	196	26	crt2	crt2	PROPN
bjp-81605	196	27	50	50	NUM
bjp-81605	196	28	µm	µm	ADP
bjp-81605	196	29	crt2	crt2	PROPN
bjp-81605	196	30	100	100	NUM
bjp-81605	196	31	µm	µm	ADP
bjp-81605	196	32	a	a	DET
bjp-81605	196	33	a	a	DET
bjp-81605	196	34	%	%	NOUN
bjp-81605	197	1	c	c	NOUN
bjp-81605	198	1	e	e	NOUN
bjp-81605	198	2	ll	ll	NOUN
bjp-81605	198	3	p	p	PROPN
bjp-81605	198	4	ro	ro	PROPN
bjp-81605	198	5	lif	lif	PROPN
bjp-81605	198	6	e	e	PROPN
bjp-81605	198	7	ra	ra	PROPN
bjp-81605	198	8	ti	ti	INTJ
bjp-81605	198	9	o	o	NOUN
bjp-81605	198	10	n	n	CCONJ
bjp-81605	198	11	125	125	NUM
bjp-81605	198	12	100	100	NUM
bjp-81605	198	13	75	75	NUM
bjp-81605	198	14	50	50	NUM
bjp-81605	198	15	25	25	NUM
bjp-81605	198	16	0	0	NUM
bjp-81605	198	17	%	%	NOUN
bjp-81605	198	18	c	c	NOUN
bjp-81605	198	19	e	e	NOUN
bjp-81605	198	20	ll	ll	AUX
bjp-81605	198	21	in	in	ADP
bjp-81605	198	22	h	h	PROPN
bjp-81605	198	23	ib	ib	NOUN
bjp-81605	198	24	it	it	PRON
bjp-81605	198	25	io	io	PROPN
bjp-81605	198	26	n	n	ADV
bjp-81605	198	27	125	125	NUM
bjp-81605	198	28	100	100	NUM
bjp-81605	198	29	75	75	NUM
bjp-81605	198	30	50	50	NUM
bjp-81605	198	31	25	25	NUM
bjp-81605	198	32	0	0	NUM
bjp-81605	198	33	ns	ns	NUM
bjp-81605	198	34	24	24	NUM
bjp-81605	198	35	hours	hour	NOUN
bjp-81605	198	36	ic50	ic50	PROPN
bjp-81605	198	37	=	=	PROPN
bjp-81605	198	38	25.1	25.1	NUM
bjp-81605	198	39	µm	µm	PART
bjp-81605	198	40	48	48	NUM
bjp-81605	198	41	hours	hour	NOUN
bjp-81605	198	42	ic50	ic50	PROPN
bjp-81605	198	43	=	=	PUNCT
bjp-81605	198	44	19.0	19.0	NUM
bjp-81605	198	45	µm	µm	PART
bjp-81605	198	46	1	1	NUM
bjp-81605	198	47	2	2	NUM
bjp-81605	198	48	4	4	NUM
bjp-81605	198	49	8	8	NUM
bjp-81605	198	50	16	16	NUM
bjp-81605	198	51	32	32	NUM
bjp-81605	198	52	64	64	NUM
bjp-81605	198	53	128	128	NUM
bjp-81605	198	54	256	256	NUM
bjp-81605	198	55	crt2	crt2	PROPN
bjp-81605	198	56	concentration	concentration	NOUN
bjp-81605	198	57	(	(	PUNCT
bjp-81605	198	58	µm	µm	NOUN
bjp-81605	198	59	)	)	PUNCT
bjp-81605	198	60	bangladesh	bangladesh	NOUN
bjp-81605	198	61	j	j	PROPN
bjp-81605	198	62	pharmacol	pharmacol	PROPN
bjp-81605	198	63	2025	2025	NUM
bjp-81605	198	64	;	;	PUNCT
bjp-81605	198	65	20	20	NUM
bjp-81605	198	66	:	:	SYM
bjp-81605	198	67	89	89	NUM
bjp-81605	198	68	-	-	SYM
bjp-81605	198	69	100	100	NUM
bjp-81605	198	70	95	95	NUM
bjp-81605	198	71	b	b	NOUN
bjp-81605	198	72	this	this	PRON
bjp-81605	198	73	subsequently	subsequently	ADV
bjp-81605	198	74	started	start	VERB
bjp-81605	198	75	mitogenic	mitogenic	ADJ
bjp-81605	198	76	,	,	PUNCT
bjp-81605	198	77	chemotactic	chemotactic	ADJ
bjp-81605	198	78	,	,	PUNCT
bjp-81605	198	79	and	and	CCONJ
bjp-81605	198	80	pro	pro	ADJ
bjp-81605	198	81	-	-	ADJ
bjp-81605	198	82	survival	survival	ADJ
bjp-81605	198	83	signals	signal	NOUN
bjp-81605	198	84	,	,	PUNCT
bjp-81605	198	85	as	as	ADV
bjp-81605	198	86	well	well	ADV
bjp-81605	198	87	as	as	ADP
bjp-81605	198	88	tumor	tumor	NOUN
bjp-81605	198	89	vascular	vascular	ADJ
bjp-81605	198	90	growth	growth	NOUN
bjp-81605	198	91	.	.	PUNCT
bjp-81605	199	1	the	the	DET
bjp-81605	199	2	vegfr1	vegfr1	NOUN
bjp-81605	199	3	expression	expression	NOUN
bjp-81605	199	4	was	be	AUX
bjp-81605	199	5	significantly	significantly	ADV
bjp-81605	199	6	reduced	reduce	VERB
bjp-81605	199	7	by	by	ADP
bjp-81605	199	8	crt2	crt2	PROPN
bjp-81605	199	9	treatment	treatment	NOUN
bjp-81605	199	10	at	at	ADP
bjp-81605	199	11	concentrations	concentration	NOUN
bjp-81605	199	12	of	of	ADP
bjp-81605	199	13	10	10	NUM
bjp-81605	199	14	and	and	CCONJ
bjp-81605	199	15	20	20	NUM
bjp-81605	199	16	µm	µm	NOUN
bjp-81605	199	17	.	.	PUNCT
bjp-81605	200	1	crt2	crt2	PROPN
bjp-81605	200	2	decreased	decrease	VERB
bjp-81605	200	3	the	the	DET
bjp-81605	200	4	fold	fold	ADJ
bjp-81605	200	5	changes	change	NOUN
bjp-81605	200	6	in	in	ADP
bjp-81605	200	7	activation	activation	NOUN
bjp-81605	200	8	phosphorylation	phosphorylation	NOUN
bjp-81605	200	9	protein	protein	NOUN
bjp-81605	200	10	via	via	ADP
bjp-81605	200	11	vegfr1	vegfr1	NOUN
bjp-81605	200	12	.	.	PUNCT
bjp-81605	201	1	the	the	DET
bjp-81605	201	2	protein	protein	NOUN
bjp-81605	201	3	fold	fold	NOUN
bjp-81605	201	4	changes	change	NOUN
bjp-81605	201	5	1.2	1.2	NUM
bjp-81605	201	6	and	and	CCONJ
bjp-81605	201	7	1.5	1.5	NUM
bjp-81605	201	8	compared	compare	VERB
bjp-81605	201	9	to	to	ADP
bjp-81605	201	10	the	the	DET
bjp-81605	201	11	control	control	NOUN
bjp-81605	201	12	groups	group	NOUN
bjp-81605	201	13	vs	vs	ADP
bjp-81605	201	14	crt	crt	ADJ
bjp-81605	201	15	treatments	treatment	NOUN
bjp-81605	201	16	.	.	PUNCT
bjp-81605	202	1	these	these	DET
bjp-81605	202	2	results	result	NOUN
bjp-81605	202	3	unequivocally	unequivocally	ADV
bjp-81605	202	4	show	show	VERB
bjp-81605	202	5	that	that	SCONJ
bjp-81605	202	6	the	the	DET
bjp-81605	202	7	constitutive	constitutive	ADJ
bjp-81605	202	8	vegfa	vegfa	ADV
bjp-81605	202	9	-	-	PUNCT
bjp-81605	202	10	induced	induce	VERB
bjp-81605	202	11	activation	activation	NOUN
bjp-81605	202	12	is	be	AUX
bjp-81605	202	13	suppressed	suppress	VERB
bjp-81605	202	14	by	by	ADP
bjp-81605	202	15	crt2	crt2	PROPN
bjp-81605	202	16	treatment	treatment	NOUN
bjp-81605	202	17	.	.	PUNCT
bjp-81605	203	1	moreover	moreover	ADV
bjp-81605	203	2	,	,	PUNCT
bjp-81605	203	3	vegfa	vegfa	PROPN
bjp-81605	203	4	/	/	SYM
bjp-81605	203	5	vegfr1	vegfr1	NOUN
bjp-81605	203	6	phosphorylates	phosphorylate	VERB
bjp-81605	203	7	several	several	ADJ
bjp-81605	203	8	downstream	downstream	ADJ
bjp-81605	203	9	substrates	substrate	NOUN
bjp-81605	203	10	of	of	ADP
bjp-81605	203	11	pi3k	pi3k	PROPN
bjp-81605	203	12	/	/	SYM
bjp-81605	203	13	akt	akt	PROPN
bjp-81605	203	14	signaling	signal	VERB
bjp-81605	203	15	which	which	PRON
bjp-81605	203	16	is	be	AUX
bjp-81605	203	17	implicated	implicate	VERB
bjp-81605	203	18	in	in	ADP
bjp-81605	203	19	important	important	ADJ
bjp-81605	203	20	physiological	physiological	ADJ
bjp-81605	203	21	processes	process	NOUN
bjp-81605	203	22	such	such	ADJ
bjp-81605	203	23	as	as	ADP
bjp-81605	203	24	cell	cell	NOUN
bjp-81605	203	25	division	division	NOUN
bjp-81605	203	26	and	and	CCONJ
bjp-81605	203	27	cell	cell	NOUN
bjp-81605	203	28	death	death	NOUN
bjp-81605	203	29	.	.	PUNCT
bjp-81605	204	1	in	in	ADP
bjp-81605	204	2	ht-116	ht-116	PROPN
bjp-81605	204	3	cells	cell	NOUN
bjp-81605	204	4	,	,	PUNCT
bjp-81605	204	5	crt2	crt2	PROPN
bjp-81605	204	6	treatment	treatment	NOUN
bjp-81605	204	7	decreased	decrease	VERB
bjp-81605	204	8	the	the	DET
bjp-81605	204	9	expression	expression	NOUN
bjp-81605	204	10	of	of	ADP
bjp-81605	204	11	pi3k	pi3k	NOUN
bjp-81605	204	12	's	's	PART
bjp-81605	204	13	regulatory	regulatory	ADJ
bjp-81605	204	14	subunit	subunit	NOUN
bjp-81605	204	15	p85	p85	NUM
bjp-81605	204	16	and	and	CCONJ
bjp-81605	204	17	a	a	DET
bjp-81605	204	18	catalytic	catalytic	ADJ
bjp-81605	204	19	subunit	subunit	NOUN
bjp-81605	204	20	,	,	PUNCT
bjp-81605	204	21	p110	p110	PROPN
bjp-81605	204	22	.	.	PUNCT
bjp-81605	205	1	by	by	ADP
bjp-81605	205	2	suppressing	suppress	VERB
bjp-81605	205	3	the	the	DET
bjp-81605	205	4	functions	function	NOUN
bjp-81605	205	5	of	of	ADP
bjp-81605	205	6	pro	pro	ADJ
bjp-81605	205	7	-	-	ADJ
bjp-81605	205	8	apoptotic	apoptotic	ADJ
bjp-81605	205	9	proteins	protein	NOUN
bjp-81605	205	10	and	and	CCONJ
bjp-81605	205	11	promoting	promote	VERB
bjp-81605	205	12	the	the	DET
bjp-81605	205	13	expression	expression	NOUN
bjp-81605	205	14	of	of	ADP
bjp-81605	205	15	cell	cell	NOUN
bjp-81605	205	16	-	-	PUNCT
bjp-81605	205	17	survival	survival	NOUN
bjp-81605	205	18	proteins	protein	NOUN
bjp-81605	205	19	,	,	PUNCT
bjp-81605	205	20	pi3k	pi3k	PROPN
bjp-81605	205	21	regulates	regulate	VERB
bjp-81605	205	22	the	the	DET
bjp-81605	205	23	phosphorylation	phosphorylation	NOUN
bjp-81605	205	24	and	and	CCONJ
bjp-81605	205	25	activation	activation	NOUN
bjp-81605	205	26	of	of	ADP
bjp-81605	205	27	akt	akt	PROPN
bjp-81605	205	28	,	,	PUNCT
bjp-81605	205	29	which	which	PRON
bjp-81605	205	30	enhances	enhance	VERB
bjp-81605	205	31	cell	cell	NOUN
bjp-81605	205	32	survival	survival	NOUN
bjp-81605	205	33	.	.	PUNCT
bjp-81605	206	1	due	due	ADP
bjp-81605	206	2	to	to	ADP
bjp-81605	206	3	crt2	crt2	PROPN
bjp-81605	206	4	's	's	PART
bjp-81605	206	5	pi3k	pi3k	NOUN
bjp-81605	206	6	inhibition	inhibition	NOUN
bjp-81605	206	7	,	,	PUNCT
bjp-81605	206	8	akt	akt	PROPN
bjp-81605	206	9	phosphorylation	phosphorylation	NOUN
bjp-81605	206	10	figure	figure	VERB
bjp-81605	206	11	5	5	NUM
bjp-81605	206	12	:	:	PUNCT
bjp-81605	206	13	mitochondrial	mitochondrial	ADJ
bjp-81605	206	14	membrane	membrane	NOUN
bjp-81605	206	15	potential	potential	NOUN
bjp-81605	206	16	measured	measure	VERB
bjp-81605	206	17	in	in	ADP
bjp-81605	206	18	the	the	DET
bjp-81605	206	19	ht-116	ht-116	NOUN
bjp-81605	206	20	cell	cell	NOUN
bjp-81605	206	21	lines	line	NOUN
bjp-81605	206	22	at	at	ADP
bjp-81605	206	23	10	10	NUM
bjp-81605	206	24	and	and	CCONJ
bjp-81605	206	25	20	20	NUM
bjp-81605	206	26	µg	µg	ADV
bjp-81605	206	27	/	/	SYM
bjp-81605	206	28	ml	ml	PROPN
bjp-81605	206	29	(	(	PUNCT
bjp-81605	206	30	jc-1	jc-1	NOUN
bjp-81605	206	31	monomer	monomer	NOUN
bjp-81605	206	32	aggregates	aggregate	NOUN
bjp-81605	206	33	are	be	AUX
bjp-81605	206	34	displayed	display	VERB
bjp-81605	206	35	in	in	ADP
bjp-81605	206	36	green	green	ADJ
bjp-81605	206	37	and	and	CCONJ
bjp-81605	206	38	red	red	ADJ
bjp-81605	206	39	)	)	PUNCT
bjp-81605	206	40	,	,	PUNCT
bjp-81605	206	41	with	with	ADP
bjp-81605	206	42	a	a	DET
bjp-81605	206	43	scale	scale	NOUN
bjp-81605	206	44	bar	bar	NOUN
bjp-81605	206	45	of	of	ADP
bjp-81605	206	46	100	100	NUM
bjp-81605	206	47	µm	µm	NOUN
bjp-81605	206	48	.	.	PUNCT
bjp-81605	207	1	the	the	DET
bjp-81605	207	2	measurement	measurement	NOUN
bjp-81605	207	3	of	of	ADP
bjp-81605	207	4	the	the	DET
bjp-81605	207	5	red	red	NOUN
bjp-81605	207	6	to	to	ADP
bjp-81605	207	7	green	green	ADJ
bjp-81605	207	8	relative	relative	ADJ
bjp-81605	207	9	fluorescence	fluorescence	NOUN
bjp-81605	207	10	of	of	ADP
bjp-81605	207	11	jc-1	jc-1	NOUN
bjp-81605	207	12	for	for	ADP
bjp-81605	207	13	control	control	NOUN
bjp-81605	207	14	,	,	PUNCT
bjp-81605	207	15	ht-116	ht-116	PROPN
bjp-81605	207	16	cells	cell	NOUN
bjp-81605	207	17	treated	treat	VERB
bjp-81605	207	18	with	with	ADP
bjp-81605	207	19	10	10	NUM
bjp-81605	207	20	and	and	CCONJ
bjp-81605	207	21	20	20	NUM
bjp-81605	207	22	µm	µm	NOUN
bjp-81605	207	23	.	.	PUNCT
bjp-81605	208	1	the	the	DET
bjp-81605	208	2	data	datum	NOUN
bjp-81605	208	3	were	be	AUX
bjp-81605	208	4	expressed	express	VERB
bjp-81605	208	5	as	as	ADP
bjp-81605	208	6	sem	sem	NOUN
bjp-81605	208	7	(	(	PUNCT
bjp-81605	208	8	n=3	n=3	NOUN
bjp-81605	208	9	)	)	PUNCT
bjp-81605	208	10	,	,	PUNCT
bjp-81605	208	11	ap<0.05	ap<0.05	NOUN
bjp-81605	208	12	and	and	CCONJ
bjp-81605	208	13	bp<0.0001	bp<0.0001	NOUN
bjp-81605	208	14	;	;	PUNCT
bjp-81605	208	15	magnification	magnification	NOUN
bjp-81605	208	16	40x	40x	NUM
bjp-81605	208	17	b	b	PROPN
bjp-81605	208	18	a	a	DET
bjp-81605	208	19	figure	figure	NOUN
bjp-81605	208	20	6	6	NUM
bjp-81605	208	21	:	:	PUNCT
bjp-81605	208	22	after	after	ADP
bjp-81605	208	23	pre	pre	ADJ
bjp-81605	208	24	-	-	ADJ
bjp-81605	208	25	treating	treat	VERB
bjp-81605	208	26	ht-116	ht-116	NOUN
bjp-81605	208	27	cell	cell	NOUN
bjp-81605	208	28	lines	line	NOUN
bjp-81605	208	29	with	with	ADP
bjp-81605	208	30	crt2	crt2	NOUN
bjp-81605	208	31	peptide	peptide	NOUN
bjp-81605	208	32	for	for	ADP
bjp-81605	208	33	24	24	NUM
bjp-81605	208	34	hours	hour	NOUN
bjp-81605	208	35	,	,	PUNCT
bjp-81605	208	36	the	the	DET
bjp-81605	208	37	cells	cell	NOUN
bjp-81605	208	38	were	be	AUX
bjp-81605	208	39	plated	plate	VERB
bjp-81605	208	40	at	at	ADP
bjp-81605	208	41	a	a	DET
bjp-81605	208	42	density	density	NOUN
bjp-81605	208	43	of	of	ADP
bjp-81605	208	44	500	500	NUM
bjp-81605	208	45	cells	cell	NOUN
bjp-81605	208	46	per	per	ADP
bjp-81605	208	47	well	well	ADV
bjp-81605	208	48	for	for	ADP
bjp-81605	208	49	15	15	NUM
bjp-81605	208	50	days	day	NOUN
bjp-81605	208	51	to	to	PART
bjp-81605	208	52	create	create	VERB
bjp-81605	208	53	colony	colony	NOUN
bjp-81605	208	54	forming	form	VERB
bjp-81605	208	55	pictures	picture	NOUN
bjp-81605	208	56	.	.	PUNCT
bjp-81605	209	1	following	follow	VERB
bjp-81605	209	2	the	the	DET
bjp-81605	209	3	colonies	colony	NOUN
bjp-81605	209	4	'	'	PART
bjp-81605	209	5	fixation	fixation	NOUN
bjp-81605	209	6	and	and	CCONJ
bjp-81605	209	7	0.5	0.5	NUM
bjp-81605	209	8	%	%	NOUN
bjp-81605	209	9	crystal	crystal	NOUN
bjp-81605	209	10	violet	violet	NOUN
bjp-81605	209	11	staining	stain	VERB
bjp-81605	209	12	(	(	PUNCT
bjp-81605	209	13	a	a	NOUN
bjp-81605	209	14	)	)	PUNCT
bjp-81605	209	15	.	.	PUNCT
bjp-81605	210	1	assay	assay	VERB
bjp-81605	210	2	for	for	ADP
bjp-81605	210	3	transwell	transwell	NOUN
bjp-81605	210	4	invasion	invasion	NOUN
bjp-81605	210	5	crt2	crt2	PROPN
bjp-81605	210	6	0	0	NUM
bjp-81605	210	7	,	,	PUNCT
bjp-81605	210	8	10	10	NUM
bjp-81605	210	9	,	,	PUNCT
bjp-81605	210	10	and	and	CCONJ
bjp-81605	210	11	20	20	NUM
bjp-81605	210	12	µg	µg	ADV
bjp-81605	210	13	/	/	SYM
bjp-81605	210	14	ml	ml	NOUN
bjp-81605	210	15	were	be	AUX
bjp-81605	210	16	used	use	VERB
bjp-81605	210	17	to	to	PART
bjp-81605	210	18	seed	seed	VERB
bjp-81605	210	19	ht-116	ht-116	NOUN
bjp-81605	210	20	cells	cell	NOUN
bjp-81605	210	21	in	in	ADP
bjp-81605	210	22	the	the	DET
bjp-81605	210	23	upper	upper	ADJ
bjp-81605	210	24	chamber	chamber	NOUN
bjp-81605	210	25	over	over	ADP
bjp-81605	210	26	a	a	DET
bjp-81605	210	27	24	24	NUM
bjp-81605	210	28	-	-	PUNCT
bjp-81605	210	29	hours	hour	NOUN
bjp-81605	210	30	period	period	NOUN
bjp-81605	210	31	.	.	PUNCT
bjp-81605	211	1	preserved	preserve	VERB
bjp-81605	211	2	,	,	PUNCT
bjp-81605	211	3	labelled	label	VERB
bjp-81605	211	4	,	,	PUNCT
bjp-81605	211	5	and	and	CCONJ
bjp-81605	211	6	counted	count	VERB
bjp-81605	211	7	the	the	DET
bjp-81605	211	8	migrating	migrating	NOUN
bjp-81605	211	9	cells	cell	NOUN
bjp-81605	211	10	in	in	ADP
bjp-81605	211	11	the	the	DET
bjp-81605	211	12	lower	low	ADJ
bjp-81605	211	13	chamber	chamber	NOUN
bjp-81605	211	14	and	and	CCONJ
bjp-81605	211	15	images	image	NOUN
bjp-81605	211	16	from	from	ADP
bjp-81605	211	17	three	three	NUM
bjp-81605	211	18	separate	separate	ADJ
bjp-81605	211	19	tests	test	NOUN
bjp-81605	211	20	(	(	PUNCT
bjp-81605	211	21	b	b	X
bjp-81605	211	22	-	-	PUNCT
bjp-81605	211	23	c	c	NOUN
bjp-81605	211	24	)	)	PUNCT
bjp-81605	211	25	.	.	PUNCT
bjp-81605	212	1	with	with	ADP
bjp-81605	212	2	respect	respect	NOUN
bjp-81605	212	3	to	to	ADP
bjp-81605	212	4	the	the	DET
bjp-81605	212	5	control	control	NOUN
bjp-81605	212	6	group	group	NOUN
bjp-81605	212	7	,	,	PUNCT
bjp-81605	212	8	data	datum	NOUN
bjp-81605	212	9	were	be	AUX
bjp-81605	212	10	mean	mean	PROPN
bjp-81605	212	11	±	±	NUM
bjp-81605	212	12	sem	sem	NOUN
bjp-81605	212	13	;	;	PUNCT
bjp-81605	212	14	n=5	n=5	NUM
bjp-81605	212	15	;	;	PUNCT
bjp-81605	212	16	ap<0.05	ap<0.05	NOUN
bjp-81605	212	17	,	,	PUNCT
bjp-81605	212	18	bp<0.01	bp<0.01	NOUN
bjp-81605	212	19	,	,	PUNCT
bjp-81605	212	20	and	and	CCONJ
bjp-81605	212	21	cp<0.0001	cp<0.0001	PROPN
bjp-81605	212	22	;	;	PUNCT
bjp-81605	212	23	magnification	magnification	NOUN
bjp-81605	212	24	40x	40x	NUM
bjp-81605	212	25	crt2	crt2	PROPN
bjp-81605	212	26	0	0	NUM
bjp-81605	212	27	10	10	NUM
bjp-81605	212	28	20	20	NUM
bjp-81605	212	29	µm	µm	ADP
bjp-81605	212	30	b	b	NOUN
bjp-81605	212	31	a	a	DET
bjp-81605	212	32	#	#	NOUN
bjp-81605	212	33	c	c	NOUN
bjp-81605	212	34	o	o	NOUN
bjp-81605	213	1	lo	lo	NOUN
bjp-81605	214	1	n	n	CCONJ
bjp-81605	214	2	y	y	NOUN
bjp-81605	214	3	f	f	NOUN
bjp-81605	214	4	o	o	PROPN
bjp-81605	214	5	rm	rm	NOUN
bjp-81605	214	6	in	in	ADP
bjp-81605	214	7	g	g	PROPN
bjp-81605	214	8	u	u	PROPN
bjp-81605	215	1	n	n	CCONJ
bjp-81605	215	2	it	it	PRON
bjp-81605	215	3	s	s	VERB
bjp-81605	215	4	125	125	NUM
bjp-81605	215	5	100	100	NUM
bjp-81605	215	6	75	75	NUM
bjp-81605	215	7	50	50	NUM
bjp-81605	215	8	25	25	NUM
bjp-81605	215	9	0	0	NUM
bjp-81605	215	10	%	%	NOUN
bjp-81605	215	11	r	r	NOUN
bjp-81605	215	12	e	e	NOUN
bjp-81605	215	13	la	la	X
bjp-81605	215	14	ti	ti	X
bjp-81605	215	15	v	v	ADP
bjp-81605	215	16	e	e	X
bjp-81605	215	17	m	m	VERB
bjp-81605	215	18	ig	ig	INTJ
bjp-81605	215	19	ra	ra	NOUN
bjp-81605	215	20	ti	ti	INTJ
bjp-81605	215	21	o	o	PROPN
bjp-81605	215	22	n	n	CCONJ
bjp-81605	215	23	a	a	PRON
bjp-81605	215	24	b	b	X
bjp-81605	215	25	ili	ili	NOUN
bjp-81605	216	1	ty	ty	INTJ
bjp-81605	216	2	125	125	NUM
bjp-81605	216	3	100	100	NUM
bjp-81605	216	4	75	75	NUM
bjp-81605	216	5	50	50	NUM
bjp-81605	216	6	25	25	NUM
bjp-81605	216	7	0	0	NUM
bjp-81605	216	8	control	control	NOUN
bjp-81605	216	9	10	10	NUM
bjp-81605	216	10	µm	µm	NUM
bjp-81605	216	11	20	20	NUM
bjp-81605	216	12	µm	µm	ADP
bjp-81605	216	13	c	c	PROPN
bjp-81605	216	14	a	a	DET
bjp-81605	216	15	b	b	NOUN
bjp-81605	216	16	c	c	NOUN
bjp-81605	216	17	c	c	NOUN
bjp-81605	216	18	crt2	crt2	PROPN
bjp-81605	216	19	0	0	NUM
bjp-81605	216	20	10	10	NUM
bjp-81605	216	21	20	20	NUM
bjp-81605	216	22	µm	µm	ADP
bjp-81605	216	23	j	j	PROPN
bjp-81605	216	24	c	c	PROPN
bjp-81605	217	1	-1	-1	PUNCT
bjp-81605	218	1	a	a	DET
bjp-81605	218	2	g	g	NOUN
bjp-81605	218	3	g	g	PROPN
bjp-81605	218	4	re	re	ADP
bjp-81605	218	5	g	g	PROPN
bjp-81605	218	6	a	a	PROPN
bjp-81605	218	7	te	te	ADP
bjp-81605	218	8	j	j	PROPN
bjp-81605	218	9	c	c	PROPN
bjp-81605	218	10	-1	-1	NOUN
bjp-81605	218	11	m	m	VERB
bjp-81605	218	12	o	o	NOUN
bjp-81605	218	13	n	n	X
bjp-81605	218	14	o	o	NOUN
bjp-81605	218	15	m	m	VERB
bjp-81605	218	16	e	e	NOUN
bjp-81605	218	17	r	r	NOUN
bjp-81605	218	18	m	m	VERB
bjp-81605	218	19	e	e	NOUN
bjp-81605	218	20	rg	rg	NOUN
bjp-81605	218	21	e	e	PROPN
bjp-81605	218	22	d	d	NOUN
bjp-81605	218	23	r	r	VERB
bjp-81605	218	24	a	a	DET
bjp-81605	218	25	ti	ti	NOUN
bjp-81605	219	1	o	o	NOUN
bjp-81605	219	2	o	o	X
bjp-81605	219	3	f	f	X
bjp-81605	219	4	re	re	X
bjp-81605	219	5	d	d	PROPN
bjp-81605	219	6	/g	/g	PUNCT
bjp-81605	219	7	re	re	VERB
bjp-81605	219	8	e	e	PROPN
bjp-81605	219	9	n	n	PROPN
bjp-81605	219	10	f	f	NOUN
bjp-81605	219	11	lu	lu	NOUN
bjp-81605	219	12	o	o	X
bjp-81605	219	13	re	re	X
bjp-81605	219	14	s	s	PROPN
bjp-81605	219	15	c	c	NOUN
bjp-81605	219	16	e	e	X
bjp-81605	219	17	n	n	NOUN
bjp-81605	219	18	c	c	NOUN
bjp-81605	219	19	e	e	X
bjp-81605	219	20	125	125	NUM
bjp-81605	219	21	100	100	NUM
bjp-81605	219	22	75	75	NUM
bjp-81605	219	23	50	50	NUM
bjp-81605	219	24	25	25	NUM
bjp-81605	219	25	0	0	NUM
bjp-81605	219	26	a	a	DET
bjp-81605	219	27	b	b	PROPN
bjp-81605	219	28	96	96	NUM
bjp-81605	219	29	bangladesh	bangladesh	NOUN
bjp-81605	219	30	j	j	PROPN
bjp-81605	219	31	pharmacol	pharmacol	PROPN
bjp-81605	219	32	2025	2025	NUM
bjp-81605	219	33	;	;	PUNCT
bjp-81605	219	34	20	20	NUM
bjp-81605	219	35	:	:	SYM
bjp-81605	219	36	89	89	NUM
bjp-81605	219	37	-	-	SYM
bjp-81605	219	38	100	100	NUM
bjp-81605	219	39	significantly	significantly	ADV
bjp-81605	219	40	dropped	drop	VERB
bjp-81605	219	41	in	in	ADP
bjp-81605	219	42	ht-116	ht-116	PROPN
bjp-81605	219	43	cells	cell	NOUN
bjp-81605	219	44	(	(	PUNCT
bjp-81605	219	45	figure	figure	NOUN
bjp-81605	219	46	9a	9a	NOUN
bjp-81605	219	47	)	)	PUNCT
bjp-81605	219	48	.	.	PUNCT
bjp-81605	220	1	the	the	DET
bjp-81605	220	2	mapk	mapk	PROPN
bjp-81605	220	3	pathway	pathway	NOUN
bjp-81605	220	4	is	be	AUX
bjp-81605	220	5	another	another	DET
bjp-81605	220	6	signaling	signal	VERB
bjp-81605	220	7	cascade	cascade	NOUN
bjp-81605	220	8	that	that	PRON
bjp-81605	220	9	is	be	AUX
bjp-81605	220	10	triggered	trigger	VERB
bjp-81605	220	11	by	by	ADP
bjp-81605	220	12	vegfr	vegfr	NOUN
bjp-81605	220	13	and	and	CCONJ
bjp-81605	220	14	is	be	AUX
bjp-81605	220	15	essential	essential	ADJ
bjp-81605	220	16	for	for	ADP
bjp-81605	220	17	regulating	regulate	VERB
bjp-81605	220	18	several	several	ADJ
bjp-81605	220	19	physiological	physiological	ADJ
bjp-81605	220	20	reactions	reaction	NOUN
bjp-81605	220	21	,	,	PUNCT
bjp-81605	220	22	including	include	VERB
bjp-81605	220	23	cell	cell	NOUN
bjp-81605	220	24	division	division	NOUN
bjp-81605	220	25	and	and	CCONJ
bjp-81605	220	26	cell	cell	NOUN
bjp-81605	220	27	death	death	NOUN
bjp-81605	220	28	.	.	PUNCT
bjp-81605	221	1	the	the	DET
bjp-81605	221	2	three	three	NUM
bjp-81605	221	3	main	main	ADJ
bjp-81605	221	4	subgroups	subgroup	NOUN
bjp-81605	221	5	of	of	ADP
bjp-81605	221	6	the	the	DET
bjp-81605	221	7	mapk	mapk	PROPN
bjp-81605	221	8	family	family	NOUN
bjp-81605	221	9	are	be	AUX
bjp-81605	221	10	p38	p38	NOUN
bjp-81605	221	11	mapk	mapk	NOUN
bjp-81605	221	12	,	,	PUNCT
bjp-81605	221	13	c	c	PROPN
bjp-81605	221	14	-	-	PUNCT
bjp-81605	221	15	jun	jun	PROPN
bjp-81605	221	16	n	n	CCONJ
bjp-81605	221	17	-	-	PUNCT
bjp-81605	221	18	terminal	terminal	ADJ
bjp-81605	221	19	kinase	kinase	NOUN
bjp-81605	221	20	(	(	PUNCT
bjp-81605	221	21	jnk	jnk	PROPN
bjp-81605	221	22	)	)	PUNCT
bjp-81605	221	23	,	,	PUNCT
bjp-81605	221	24	and	and	CCONJ
bjp-81605	221	25	extracellular	extracellular	ADJ
bjp-81605	221	26	signal	signal	NOUN
bjp-81605	221	27	-	-	PUNCT
bjp-81605	221	28	regulated	regulate	VERB
bjp-81605	221	29	protein	protein	NOUN
bjp-81605	221	30	kinase	kinase	NOUN
bjp-81605	221	31	(	(	PUNCT
bjp-81605	221	32	erk	erk	PROPN
bjp-81605	221	33	)	)	PUNCT
bjp-81605	221	34	.	.	PUNCT
bjp-81605	222	1	while	while	SCONJ
bjp-81605	222	2	jnk	jnk	PROPN
bjp-81605	222	3	and	and	CCONJ
bjp-81605	222	4	p38	p38	NOUN
bjp-81605	222	5	mapks	mapks	NOUN
bjp-81605	222	6	are	be	AUX
bjp-81605	222	7	involved	involve	VERB
bjp-81605	222	8	in	in	ADP
bjp-81605	222	9	apoptotic	apoptotic	ADJ
bjp-81605	222	10	cell	cell	NOUN
bjp-81605	222	11	death	death	NOUN
bjp-81605	222	12	,	,	PUNCT
bjp-81605	222	13	erks	erk	NOUN
bjp-81605	222	14	are	be	AUX
bjp-81605	222	15	involved	involve	VERB
bjp-81605	222	16	in	in	ADP
bjp-81605	222	17	the	the	DET
bjp-81605	222	18	regulation	regulation	NOUN
bjp-81605	222	19	of	of	ADP
bjp-81605	222	20	mitogen	mitogen	NOUN
bjp-81605	222	21	-	-	PUNCT
bjp-81605	222	22	activated	activate	VERB
bjp-81605	222	23	proliferation	proliferation	NOUN
bjp-81605	222	24	/	/	SYM
bjp-81605	222	25	differentiation	differentiation	NOUN
bjp-81605	222	26	factors	factor	NOUN
bjp-81605	222	27	(	(	PUNCT
bjp-81605	222	28	figure	figure	NOUN
bjp-81605	222	29	9b	9b	NUM
bjp-81605	222	30	)	)	PUNCT
bjp-81605	222	31	.	.	PUNCT
bjp-81605	223	1	the	the	DET
bjp-81605	223	2	crt2	crt2	PROPN
bjp-81605	223	3	therapy	therapy	NOUN
bjp-81605	223	4	significantly	significantly	ADV
bjp-81605	223	5	reduced	reduce	VERB
bjp-81605	223	6	p38	p38	NOUN
bjp-81605	223	7	,	,	PUNCT
bjp-81605	223	8	jnk1/2	jnk1/2	PROPN
bjp-81605	223	9	,	,	PUNCT
bjp-81605	223	10	and	and	CCONJ
bjp-81605	223	11	erk1/2	erk1/2	PROPN
bjp-81605	223	12	phosphorylation	phosphorylation	NOUN
bjp-81605	223	13	in	in	ADP
bjp-81605	223	14	ht-116	ht-116	PROPN
bjp-81605	223	15	cells	cell	NOUN
bjp-81605	223	16	by	by	ADP
bjp-81605	223	17	1.2	1.2	NUM
bjp-81605	223	18	to	to	PART
bjp-81605	223	19	1.5	1.5	NUM
bjp-81605	223	20	-	-	PUNCT
bjp-81605	223	21	fold	fold	ADJ
bjp-81605	223	22	reduction	reduction	NOUN
bjp-81605	223	23	.	.	PUNCT
bjp-81605	224	1	figure	figure	VERB
bjp-81605	224	2	7	7	NUM
bjp-81605	224	3	:	:	PUNCT
bjp-81605	224	4	effects	effect	NOUN
bjp-81605	224	5	of	of	ADP
bjp-81605	224	6	crt2	crt2	PROPN
bjp-81605	224	7	on	on	ADP
bjp-81605	224	8	apoptosis	apoptosis	NOUN
bjp-81605	224	9	(	(	PUNCT
bjp-81605	224	10	a	a	DET
bjp-81605	224	11	-	-	PUNCT
bjp-81605	224	12	b	b	NOUN
bjp-81605	224	13	)	)	PUNCT
bjp-81605	224	14	and	and	CCONJ
bjp-81605	224	15	proteins	protein	NOUN
bjp-81605	224	16	bax	bax	NOUN
bjp-81605	224	17	/	/	SYM
bjp-81605	224	18	bcl-2	bcl-2	PUNCT
bjp-81605	224	19	(	(	PUNCT
bjp-81605	224	20	c	c	NOUN
bjp-81605	224	21	)	)	PUNCT
bjp-81605	224	22	of	of	ADP
bjp-81605	224	23	ht-116	ht-116	NOUN
bjp-81605	224	24	cells	cell	NOUN
bjp-81605	224	25	.	.	PUNCT
bjp-81605	225	1	with	with	ADP
bjp-81605	225	2	respect	respect	NOUN
bjp-81605	225	3	to	to	ADP
bjp-81605	225	4	the	the	DET
bjp-81605	225	5	control	control	NOUN
bjp-81605	225	6	group	group	NOUN
bjp-81605	225	7	,	,	PUNCT
bjp-81605	225	8	data	datum	NOUN
bjp-81605	225	9	were	be	AUX
bjp-81605	225	10	expressed	express	VERB
bjp-81605	225	11	as	as	ADP
bjp-81605	225	12	mean	mean	PROPN
bjp-81605	225	13	±	±	NUM
bjp-81605	225	14	sem	sem	NOUN
bjp-81605	225	15	;	;	PUNCT
bjp-81605	225	16	n=5	n=5	NUM
bjp-81605	225	17	;	;	PUNCT
bjp-81605	225	18	ap<0.05	ap<0.05	NOUN
bjp-81605	225	19	;	;	PUNCT
bjp-81605	225	20	bp<0.01	bp<0.01	PROPN
bjp-81605	225	21	b	b	PROPN
bjp-81605	225	22	a	a	DET
bjp-81605	225	23	c	c	NOUN
bjp-81605	225	24	figure	figure	NOUN
bjp-81605	225	25	8	8	NUM
bjp-81605	225	26	:	:	PUNCT
bjp-81605	225	27	effects	effect	NOUN
bjp-81605	225	28	of	of	ADP
bjp-81605	225	29	crt2	crt2	PROPN
bjp-81605	225	30	on	on	ADP
bjp-81605	225	31	cell	cell	NOUN
bjp-81605	225	32	cycle	cycle	NOUN
bjp-81605	225	33	analysis	analysis	NOUN
bjp-81605	225	34	using	use	VERB
bjp-81605	225	35	flow	flow	NOUN
bjp-81605	225	36	cytometry	cytometry	NOUN
bjp-81605	225	37	analysis	analysis	NOUN
bjp-81605	225	38	(	(	PUNCT
bjp-81605	225	39	a	a	X
bjp-81605	225	40	)	)	PUNCT
bjp-81605	225	41	,	,	PUNCT
bjp-81605	225	42	dna	dna	PROPN
bjp-81605	225	43	content	content	NOUN
bjp-81605	225	44	(	(	PUNCT
bjp-81605	225	45	b	b	NOUN
bjp-81605	225	46	)	)	PUNCT
bjp-81605	225	47	,	,	PUNCT
bjp-81605	225	48	and	and	CCONJ
bjp-81605	225	49	cyclin	cyclin	NOUN
bjp-81605	225	50	-	-	PUNCT
bjp-81605	225	51	d	d	PROPN
bjp-81605	225	52	/	/	SYM
bjp-81605	225	53	p21	p21	NOUN
bjp-81605	225	54	proteins	protein	NOUN
bjp-81605	225	55	(	(	PUNCT
bjp-81605	225	56	c	c	NOUN
bjp-81605	225	57	)	)	PUNCT
bjp-81605	225	58	in	in	ADP
bjp-81605	225	59	ht-116	ht-116	PROPN
bjp-81605	225	60	cells	cell	NOUN
bjp-81605	225	61	.	.	PUNCT
bjp-81605	226	1	data	datum	NOUN
bjp-81605	226	2	were	be	AUX
bjp-81605	226	3	mean	mean	PROPN
bjp-81605	226	4	±	±	NUM
bjp-81605	226	5	sem	sem	NOUN
bjp-81605	226	6	;	;	PUNCT
bjp-81605	226	7	n=5	n=5	PROPN
bjp-81605	226	8	b	b	NOUN
bjp-81605	226	9	a	a	DET
bjp-81605	226	10	c	c	NOUN
bjp-81605	226	11	h	h	NOUN
bjp-81605	226	12	t	t	NOUN
bjp-81605	226	13	-1	-1	NOUN
bjp-81605	226	14	1	1	NUM
bjp-81605	226	15	6	6	NUM
bjp-81605	226	16	%	%	NOUN
bjp-81605	226	17	d	d	NOUN
bjp-81605	226	18	n	n	NOUN
bjp-81605	226	19	a	a	DET
bjp-81605	226	20	c	c	NOUN
bjp-81605	226	21	o	o	NOUN
bjp-81605	226	22	n	n	X
bjp-81605	226	23	te	te	INTJ
bjp-81605	226	24	n	n	X
bjp-81605	226	25	t	t	NOUN
bjp-81605	226	26	in	in	ADP
bjp-81605	226	27	c	c	NOUN
bjp-81605	226	28	e	e	X
bjp-81605	226	29	lls	ll	VERB
bjp-81605	226	30	100	100	NUM
bjp-81605	226	31	80	80	NUM
bjp-81605	226	32	60	60	NUM
bjp-81605	226	33	40	40	NUM
bjp-81605	226	34	20	20	NUM
bjp-81605	226	35	0	0	NUM
bjp-81605	226	36	control	control	NOUN
bjp-81605	226	37	10	10	NUM
bjp-81605	226	38	µm	µm	PART
bjp-81605	226	39	20	20	NUM
bjp-81605	226	40	µm	µm	ADP
bjp-81605	226	41	g0	g0	PROPN
bjp-81605	226	42	/	/	SYM
bjp-81605	226	43	g1	g1	PROPN
bjp-81605	226	44	s	s	PART
bjp-81605	226	45	g2	g2	PROPN
bjp-81605	226	46	/	/	SYM
bjp-81605	226	47	m	m	PROPN
bjp-81605	226	48	0	0	NUM
bjp-81605	226	49	10	10	NUM
bjp-81605	226	50	20	20	NUM
bjp-81605	226	51	crt2	crt2	PROPN
bjp-81605	226	52	concentration	concentration	NOUN
bjp-81605	226	53	(	(	PUNCT
bjp-81605	226	54	µm	µm	NOUN
bjp-81605	226	55	)	)	PUNCT
bjp-81605	226	56	0	0	NUM
bjp-81605	226	57	10	10	NUM
bjp-81605	226	58	20	20	NUM
bjp-81605	226	59	crt2	crt2	PROPN
bjp-81605	226	60	concentration	concentration	NOUN
bjp-81605	226	61	(	(	PUNCT
bjp-81605	226	62	µm	µm	NOUN
bjp-81605	226	63	)	)	PUNCT
bjp-81605	226	64	21	21	NUM
bjp-81605	226	65	kda	kda	NOUN
bjp-81605	226	66	34	34	NUM
bjp-81605	227	1	kda	kda	NOUN
bjp-81605	227	2	42	42	NUM
bjp-81605	227	3	kda	kda	NOUN
bjp-81605	227	4	p21	p21	PROPN
bjp-81605	227	5	cyclin	cyclin	PROPN
bjp-81605	227	6	-	-	PUNCT
bjp-81605	227	7	d1	d1	PROPN
bjp-81605	227	8	β	β	NOUN
bjp-81605	227	9	-	-	NOUN
bjp-81605	227	10	actin	actin	ADJ
bjp-81605	227	11	18	18	NUM
bjp-81605	227	12	kda	kda	NOUN
bjp-81605	227	13	26	26	NUM
bjp-81605	227	14	kda	kda	NOUN
bjp-81605	227	15	23	23	NUM
bjp-81605	227	16	kda	kda	NOUN
bjp-81605	227	17	42	42	NUM
bjp-81605	227	18	kda	kda	NOUN
bjp-81605	227	19	c	c	NOUN
bjp-81605	227	20	-	-	PUNCT
bjp-81605	227	21	prap	prap	NOUN
bjp-81605	227	22	bcl-2	bcl-2	VERB
bjp-81605	227	23	bax	bax	PROPN
bjp-81605	227	24	β	β	PROPN
bjp-81605	227	25	-	-	PUNCT
bjp-81605	227	26	actin	actin	ADJ
bjp-81605	227	27	control	control	NOUN
bjp-81605	227	28	10	10	NUM
bjp-81605	227	29	µm	µm	PART
bjp-81605	227	30	20	20	NUM
bjp-81605	227	31	µm	µm	ADP
bjp-81605	227	32	h	h	PROPN
bjp-81605	227	33	t	t	NOUN
bjp-81605	227	34	-1	-1	NOUN
bjp-81605	227	35	1	1	NUM
bjp-81605	227	36	6	6	NUM
bjp-81605	227	37	%	%	NOUN
bjp-81605	227	38	a	a	DET
bjp-81605	227	39	p	p	NOUN
bjp-81605	227	40	o	o	X
bjp-81605	227	41	p	p	NOUN
bjp-81605	227	42	to	to	ADP
bjp-81605	227	43	s	s	PRON
bjp-81605	227	44	is	be	AUX
bjp-81605	227	45	b	b	PROPN
bjp-81605	227	46	a	a	DET
bjp-81605	227	47	bangladesh	bangladesh	NOUN
bjp-81605	227	48	j	j	PROPN
bjp-81605	227	49	pharmacol	pharmacol	PROPN
bjp-81605	227	50	2025	2025	NUM
bjp-81605	227	51	;	;	PUNCT
bjp-81605	227	52	20	20	NUM
bjp-81605	227	53	:	:	SYM
bjp-81605	227	54	89	89	NUM
bjp-81605	227	55	-	-	SYM
bjp-81605	227	56	100	100	NUM
bjp-81605	227	57	97	97	NUM
bjp-81605	227	58	discussion	discussion	NOUN
bjp-81605	227	59	in	in	ADP
bjp-81605	227	60	the	the	DET
bjp-81605	227	61	current	current	ADJ
bjp-81605	227	62	study	study	NOUN
bjp-81605	227	63	,	,	PUNCT
bjp-81605	227	64	the	the	DET
bjp-81605	227	65	crt2	crt2	PROPN
bjp-81605	227	66	peptide	peptide	NOUN
bjp-81605	227	67	was	be	AUX
bjp-81605	227	68	successfully	successfully	ADV
bjp-81605	227	69	synthesized	synthesize	VERB
bjp-81605	227	70	,	,	PUNCT
bjp-81605	227	71	exhibiting	exhibit	VERB
bjp-81605	227	72	a	a	DET
bjp-81605	227	73	molecular	molecular	ADJ
bjp-81605	227	74	weight	weight	NOUN
bjp-81605	227	75	of	of	ADP
bjp-81605	227	76	2,228.8kda	2,228.8kda	NUM
bjp-81605	227	77	and	and	CCONJ
bjp-81605	227	78	a	a	DET
bjp-81605	227	79	purity	purity	NOUN
bjp-81605	227	80	of	of	ADP
bjp-81605	227	81	≥95	≥95	NOUN
bjp-81605	227	82	%	%	NOUN
bjp-81605	227	83	.	.	PUNCT
bjp-81605	228	1	the	the	DET
bjp-81605	228	2	peptide	peptide	NOUN
bjp-81605	228	3	contains	contain	VERB
bjp-81605	228	4	six	six	NUM
bjp-81605	228	5	positively	positively	ADV
bjp-81605	228	6	charged	charge	VERB
bjp-81605	228	7	residues	residue	NOUN
bjp-81605	228	8	and	and	CCONJ
bjp-81605	228	9	is	be	AUX
bjp-81605	228	10	hydrophilic	hydrophilic	ADJ
bjp-81605	228	11	.	.	PUNCT
bjp-81605	229	1	structurally	structurally	ADV
bjp-81605	229	2	,	,	PUNCT
bjp-81605	229	3	one	one	NUM
bjp-81605	229	4	side	side	NOUN
bjp-81605	229	5	of	of	ADP
bjp-81605	229	6	the	the	DET
bjp-81605	229	7	α	α	NOUN
bjp-81605	229	8	-	-	PUNCT
bjp-81605	229	9	helix	helix	NOUN
bjp-81605	229	10	is	be	AUX
bjp-81605	229	11	composed	compose	VERB
bjp-81605	229	12	of	of	ADP
bjp-81605	229	13	methionine	methionine	NOUN
bjp-81605	229	14	residues	residue	NOUN
bjp-81605	229	15	,	,	PUNCT
bjp-81605	229	16	making	make	VERB
bjp-81605	229	17	it	it	PRON
bjp-81605	229	18	hydrophobic	hydrophobic	NOUN
bjp-81605	229	19	,	,	PUNCT
bjp-81605	229	20	while	while	SCONJ
bjp-81605	229	21	the	the	DET
bjp-81605	229	22	opposite	opposite	ADJ
bjp-81605	229	23	side	side	NOUN
bjp-81605	229	24	consists	consist	VERB
bjp-81605	229	25	of	of	ADP
bjp-81605	229	26	polar	polar	ADJ
bjp-81605	229	27	and	and	CCONJ
bjp-81605	229	28	hydrophilic	hydrophilic	ADJ
bjp-81605	229	29	amino	amino	NOUN
bjp-81605	229	30	acids	acid	NOUN
bjp-81605	229	31	.	.	PUNCT
bjp-81605	230	1	this	this	DET
bjp-81605	230	2	amphipathic	amphipathic	ADJ
bjp-81605	230	3	configuration	configuration	NOUN
bjp-81605	230	4	characterizes	characterize	VERB
bjp-81605	230	5	the	the	DET
bjp-81605	230	6	crt2	crt2	PROPN
bjp-81605	230	7	peptide	peptide	NOUN
bjp-81605	230	8	.	.	PUNCT
bjp-81605	231	1	as	as	ADP
bjp-81605	231	2	a	a	DET
bjp-81605	231	3	cationic	cationic	ADJ
bjp-81605	231	4	amphipathic	amphipathic	ADJ
bjp-81605	231	5	peptide	peptide	NOUN
bjp-81605	231	6	,	,	PUNCT
bjp-81605	231	7	crt2	crt2	PROPN
bjp-81605	231	8	can	can	AUX
bjp-81605	231	9	induce	induce	VERB
bjp-81605	231	10	membrane	membrane	NOUN
bjp-81605	231	11	instability	instability	NOUN
bjp-81605	231	12	,	,	PUNCT
bjp-81605	231	13	leading	lead	VERB
bjp-81605	231	14	to	to	ADP
bjp-81605	231	15	cell	cell	NOUN
bjp-81605	231	16	proliferation	proliferation	NOUN
bjp-81605	231	17	and	and	CCONJ
bjp-81605	231	18	cell	cell	NOUN
bjp-81605	231	19	death	death	NOUN
bjp-81605	231	20	.	.	PUNCT
bjp-81605	232	1	molecular	molecular	ADJ
bjp-81605	232	2	docking	docking	NOUN
bjp-81605	232	3	analysis	analysis	NOUN
bjp-81605	232	4	revealed	reveal	VERB
bjp-81605	232	5	a	a	DET
bjp-81605	232	6	strong	strong	ADJ
bjp-81605	232	7	binding	bind	VERB
bjp-81605	232	8	affinity	affinity	NOUN
bjp-81605	232	9	between	between	ADP
bjp-81605	232	10	crt2	crt2	PROPN
bjp-81605	232	11	and	and	CCONJ
bjp-81605	232	12	vegfr1	vegfr1	PROPN
bjp-81605	232	13	,	,	PUNCT
bjp-81605	232	14	with	with	ADP
bjp-81605	232	15	a	a	DET
bjp-81605	232	16	minimum	minimum	ADJ
bjp-81605	232	17	binding	bind	VERB
bjp-81605	232	18	energy	energy	NOUN
bjp-81605	232	19	of	of	ADP
bjp-81605	232	20	–	–	PUNCT
bjp-81605	232	21	37.05	37.05	NUM
bjp-81605	232	22	kcal	kcal	PROPN
bjp-81605	232	23	/	/	SYM
bjp-81605	232	24	mol	mol	PROPN
bjp-81605	232	25	.	.	PUNCT
bjp-81605	233	1	this	this	DET
bjp-81605	233	2	binding	bind	VERB
bjp-81605	233	3	interaction	interaction	NOUN
bjp-81605	233	4	was	be	AUX
bjp-81605	233	5	visualized	visualize	VERB
bjp-81605	233	6	through	through	ADP
bjp-81605	233	7	structural	structural	ADJ
bjp-81605	233	8	superimposition	superimposition	NOUN
bjp-81605	233	9	,	,	PUNCT
bjp-81605	233	10	which	which	PRON
bjp-81605	233	11	showed	show	VERB
bjp-81605	233	12	that	that	SCONJ
bjp-81605	233	13	crt2	crt2	PROPN
bjp-81605	233	14	interacts	interact	VERB
bjp-81605	233	15	with	with	ADP
bjp-81605	233	16	several	several	ADJ
bjp-81605	233	17	key	key	ADJ
bjp-81605	233	18	residues	residue	NOUN
bjp-81605	233	19	in	in	ADP
bjp-81605	233	20	the	the	DET
bjp-81605	233	21	vegf	vegf	PROPN
bjp-81605	233	22	-	-	PUNCT
bjp-81605	233	23	b	b	PROPN
bjp-81605	233	24	/	/	SYM
bjp-81605	233	25	vegfr1	vegfr1	NOUN
bjp-81605	233	26	complex	complex	NOUN
bjp-81605	233	27	,	,	PUNCT
bjp-81605	233	28	including	include	VERB
bjp-81605	233	29	glu59	glu59	PROPN
bjp-81605	233	30	,	,	PUNCT
bjp-81605	233	31	his145	his145	PROPN
bjp-81605	233	32	,	,	PUNCT
bjp-81605	233	33	gln146	gln146	PROPN
bjp-81605	233	34	,	,	PUNCT
bjp-81605	233	35	ser186	ser186	PROPN
bjp-81605	233	36	,	,	PUNCT
bjp-81605	233	37	trp226	trp226	NOUN
bjp-81605	233	38	,	,	PUNCT
bjp-81605	233	39	arg225	arg225	PROPN
bjp-81605	233	40	,	,	PUNCT
bjp-81605	233	41	and	and	CCONJ
bjp-81605	233	42	lys265	lys265	NOUN
bjp-81605	233	43	.	.	PUNCT
bjp-81605	234	1	these	these	DET
bjp-81605	234	2	interactions	interaction	NOUN
bjp-81605	234	3	involve	involve	VERB
bjp-81605	234	4	both	both	CCONJ
bjp-81605	234	5	hydrophobic	hydrophobic	NOUN
bjp-81605	234	6	and	and	CCONJ
bjp-81605	234	7	van	van	PROPN
bjp-81605	234	8	der	der	NOUN
bjp-81605	234	9	waals	waal	NOUN
bjp-81605	234	10	forces	force	NOUN
bjp-81605	234	11	.	.	PUNCT
bjp-81605	235	1	notably	notably	ADV
bjp-81605	235	2	,	,	PUNCT
bjp-81605	235	3	the	the	DET
bjp-81605	235	4	most	most	ADV
bjp-81605	235	5	hydrophobic	hydrophobic	ADJ
bjp-81605	235	6	amino	amino	NOUN
bjp-81605	235	7	acid	acid	NOUN
bjp-81605	235	8	residues	residue	NOUN
bjp-81605	235	9	of	of	ADP
bjp-81605	235	10	crt2	crt2	PROPN
bjp-81605	235	11	—	—	PUNCT
bjp-81605	235	12	arg4	arg4	NOUN
bjp-81605	235	13	,	,	PUNCT
bjp-81605	235	14	ser9	ser9	ADJ
bjp-81605	235	15	,	,	PUNCT
bjp-81605	235	16	tyr10	tyr10	NOUN
bjp-81605	235	17	,	,	PUNCT
bjp-81605	235	18	and	and	CCONJ
bjp-81605	235	19	mept19	mept19	NOUN
bjp-81605	235	20	participated	participate	VERB
bjp-81605	235	21	in	in	ADP
bjp-81605	235	22	van	van	PROPN
bjp-81605	235	23	der	der	NOUN
bjp-81605	235	24	waals	waal	NOUN
bjp-81605	235	25	interactions	interaction	NOUN
bjp-81605	235	26	,	,	PUNCT
bjp-81605	235	27	contributing	contribute	VERB
bjp-81605	235	28	to	to	ADP
bjp-81605	235	29	the	the	DET
bjp-81605	235	30	peptide	peptide	NOUN
bjp-81605	235	31	's	's	PART
bjp-81605	235	32	strong	strong	ADJ
bjp-81605	235	33	binding	binding	ADJ
bjp-81605	235	34	and	and	CCONJ
bjp-81605	235	35	potential	potential	ADJ
bjp-81605	235	36	anti	anti	ADJ
bjp-81605	235	37	-	-	ADJ
bjp-81605	235	38	cancer	cancer	ADJ
bjp-81605	235	39	activity	activity	NOUN
bjp-81605	235	40	.	.	PUNCT
bjp-81605	236	1	similarly	similarly	ADV
bjp-81605	236	2	,	,	PUNCT
bjp-81605	236	3	in	in	ADP
bjp-81605	236	4	vitro	vitro	X
bjp-81605	236	5	studies	study	NOUN
bjp-81605	236	6	revealed	reveal	VERB
bjp-81605	236	7	that	that	SCONJ
bjp-81605	236	8	crt2	crt2	PROPN
bjp-81605	236	9	binds	bind	VERB
bjp-81605	236	10	to	to	ADP
bjp-81605	236	11	vegfr1	vegfr1	NOUN
bjp-81605	236	12	on	on	ADP
bjp-81605	236	13	the	the	DET
bjp-81605	236	14	surface	surface	NOUN
bjp-81605	236	15	of	of	ADP
bjp-81605	236	16	epithelial	epithelial	ADJ
bjp-81605	236	17	cells	cell	NOUN
bjp-81605	236	18	and	and	CCONJ
bjp-81605	236	19	competes	compete	VERB
bjp-81605	236	20	with	with	ADP
bjp-81605	236	21	antibodies	antibody	NOUN
bjp-81605	236	22	that	that	PRON
bjp-81605	236	23	recognize	recognize	VERB
bjp-81605	236	24	the	the	DET
bjp-81605	236	25	extracellular	extracellular	ADJ
bjp-81605	236	26	domains	domain	NOUN
bjp-81605	236	27	of	of	ADP
bjp-81605	236	28	the	the	DET
bjp-81605	236	29	receptors	receptor	NOUN
bjp-81605	236	30	.	.	PUNCT
bjp-81605	237	1	based	base	VERB
bjp-81605	237	2	on	on	ADP
bjp-81605	237	3	the	the	DET
bjp-81605	237	4	mmt	mmt	PROPN
bjp-81605	237	5	assay	assay	NOUN
bjp-81605	237	6	,	,	PUNCT
bjp-81605	237	7	the	the	DET
bjp-81605	237	8	results	result	NOUN
bjp-81605	237	9	of	of	ADP
bjp-81605	237	10	crt2	crt2	PROPN
bjp-81605	237	11	treatment	treatment	NOUN
bjp-81605	237	12	in	in	ADP
bjp-81605	237	13	ht-116	ht-116	PROPN
bjp-81605	237	14	cells	cell	NOUN
bjp-81605	237	15	were	be	AUX
bjp-81605	237	16	16.0	16.0	NUM
bjp-81605	237	17	±	±	NUM
bjp-81605	237	18	1.3	1.3	NUM
bjp-81605	237	19	μg	μg	NOUN
bjp-81605	237	20	/	/	SYM
bjp-81605	237	21	ml	ml	NOUN
bjp-81605	237	22	,	,	PUNCT
bjp-81605	237	23	respectively	respectively	ADV
bjp-81605	237	24	.	.	PUNCT
bjp-81605	238	1	annexin	annexin	PROPN
bjp-81605	238	2	v	v	PROPN
bjp-81605	238	3	-	-	PUNCT
bjp-81605	238	4	fitc	fitc	NOUN
bjp-81605	238	5	(	(	PUNCT
bjp-81605	238	6	fluorescein	fluorescein	NOUN
bjp-81605	238	7	isothiocyanate	isothiocyanate	NOUN
bjp-81605	238	8	)	)	PUNCT
bjp-81605	238	9	and	and	CCONJ
bjp-81605	238	10	propidium	propidium	NOUN
bjp-81605	238	11	iodide	iodide	NOUN
bjp-81605	238	12	double	double	ADJ
bjp-81605	238	13	labeling	labeling	NOUN
bjp-81605	238	14	after	after	SCONJ
bjp-81605	238	15	crt2	crt2	PROPN
bjp-81605	238	16	treatment	treatment	NOUN
bjp-81605	238	17	confirmed	confirm	VERB
bjp-81605	238	18	its	its	PRON
bjp-81605	238	19	ability	ability	NOUN
bjp-81605	238	20	to	to	PART
bjp-81605	238	21	induce	induce	VERB
bjp-81605	238	22	apoptosis	apoptosis	NOUN
bjp-81605	238	23	and	and	CCONJ
bjp-81605	238	24	cell	cell	NOUN
bjp-81605	238	25	cycle	cycle	NOUN
bjp-81605	238	26	arrest	arrest	NOUN
bjp-81605	238	27	.	.	PUNCT
bjp-81605	239	1	apoptosis	apoptosis	NOUN
bjp-81605	239	2	is	be	AUX
bjp-81605	239	3	down	down	ADV
bjp-81605	239	4	-	-	PUNCT
bjp-81605	239	5	regulated	regulate	VERB
bjp-81605	239	6	when	when	SCONJ
bjp-81605	239	7	vegfr	vegfr	NOUN
bjp-81605	239	8	,	,	PUNCT
bjp-81605	239	9	pi3k	pi3k	PROPN
bjp-81605	239	10	/	/	SYM
bjp-81605	239	11	akt	akt	PROPN
bjp-81605	239	12	,	,	PUNCT
bjp-81605	239	13	or	or	CCONJ
bjp-81605	239	14	mapk	mapk	NOUN
bjp-81605	239	15	are	be	AUX
bjp-81605	239	16	activated	activate	VERB
bjp-81605	239	17	;	;	PUNCT
bjp-81605	239	18	therefore	therefore	ADV
bjp-81605	239	19	,	,	PUNCT
bjp-81605	239	20	one	one	NUM
bjp-81605	239	21	of	of	ADP
bjp-81605	239	22	the	the	DET
bjp-81605	239	23	most	most	ADV
bjp-81605	239	24	obvious	obvious	ADJ
bjp-81605	239	25	targets	target	NOUN
bjp-81605	239	26	for	for	ADP
bjp-81605	239	27	cancer	cancer	NOUN
bjp-81605	239	28	therapy	therapy	NOUN
bjp-81605	239	29	is	be	AUX
bjp-81605	239	30	apoptosis	apoptosis	NOUN
bjp-81605	239	31	activation	activation	NOUN
bjp-81605	239	32	(	(	PUNCT
bjp-81605	239	33	tokunaga	tokunaga	NOUN
bjp-81605	239	34	et	et	PROPN
bjp-81605	239	35	al	al	PROPN
bjp-81605	239	36	.	.	PROPN
bjp-81605	239	37	,	,	PUNCT
bjp-81605	239	38	2008	2008	NUM
bjp-81605	239	39	)	)	PUNCT
bjp-81605	239	40	.	.	PUNCT
bjp-81605	240	1	antiapoptotic	antiapoptotic	PROPN
bjp-81605	240	2	(	(	PUNCT
bjp-81605	240	3	bax	bax	NOUN
bjp-81605	240	4	and	and	CCONJ
bjp-81605	240	5	bak	bak	NOUN
bjp-81605	240	6	)	)	PUNCT
bjp-81605	240	7	and	and	CCONJ
bjp-81605	240	8	pro	pro	ADJ
bjp-81605	240	9	-	-	ADJ
bjp-81605	240	10	apoptotic	apoptotic	ADJ
bjp-81605	240	11	(	(	PUNCT
bjp-81605	240	12	bcl2	bcl2	PROPN
bjp-81605	240	13	,	,	PUNCT
bjp-81605	240	14	bclxl	bclxl	NOUN
bjp-81605	240	15	,	,	PUNCT
bjp-81605	240	16	and	and	CCONJ
bjp-81605	240	17	mcl-1	mcl-1	X
bjp-81605	240	18	)	)	PUNCT
bjp-81605	240	19	proteins	protein	NOUN
bjp-81605	240	20	make	make	VERB
bjp-81605	240	21	up	up	ADP
bjp-81605	240	22	the	the	DET
bjp-81605	240	23	bcl2	bcl2	NOUN
bjp-81605	240	24	family	family	NOUN
bjp-81605	240	25	of	of	ADP
bjp-81605	240	26	proteins	protein	NOUN
bjp-81605	240	27	,	,	PUNCT
bjp-81605	240	28	which	which	PRON
bjp-81605	240	29	are	be	AUX
bjp-81605	240	30	significant	significant	ADJ
bjp-81605	240	31	apoptotic	apoptotic	ADJ
bjp-81605	240	32	regulators	regulator	NOUN
bjp-81605	240	33	(	(	PUNCT
bjp-81605	240	34	mc	mc	PROPN
bjp-81605	240	35	cubrey	cubrey	PROPN
bjp-81605	240	36	et	et	PROPN
bjp-81605	240	37	al	al	PROPN
bjp-81605	240	38	.	.	PROPN
bjp-81605	240	39	,	,	PUNCT
bjp-81605	240	40	2006	2006	NUM
bjp-81605	240	41	)	)	PUNCT
bjp-81605	240	42	.	.	PUNCT
bjp-81605	241	1	when	when	SCONJ
bjp-81605	241	2	crt2	crt2	PROPN
bjp-81605	241	3	was	be	AUX
bjp-81605	241	4	applied	apply	VERB
bjp-81605	241	5	to	to	ADP
bjp-81605	241	6	colorectal	colorectal	ADJ
bjp-81605	241	7	cancer	cancer	NOUN
bjp-81605	241	8	cell	cell	NOUN
bjp-81605	241	9	lines	line	NOUN
bjp-81605	241	10	,	,	PUNCT
bjp-81605	241	11	the	the	DET
bjp-81605	241	12	anti	anti	ADJ
bjp-81605	241	13	-	-	ADJ
bjp-81605	241	14	apoptotic	apoptotic	ADJ
bjp-81605	241	15	protein	protein	NOUN
bjp-81605	241	16	bcl2	bcl2	NOUN
bjp-81605	241	17	was	be	AUX
bjp-81605	241	18	found	find	VERB
bjp-81605	241	19	to	to	PART
bjp-81605	241	20	be	be	AUX
bjp-81605	241	21	less	less	ADV
bjp-81605	241	22	expressed	express	VERB
bjp-81605	241	23	,	,	PUNCT
bjp-81605	241	24	whereas	whereas	SCONJ
bjp-81605	241	25	the	the	DET
bjp-81605	241	26	proapoptotic	proapoptotic	ADJ
bjp-81605	241	27	protein	protein	NOUN
bjp-81605	241	28	bax	bax	PROPN
bjp-81605	241	29	was	be	AUX
bjp-81605	241	30	more	more	ADV
bjp-81605	241	31	expressed	express	VERB
bjp-81605	241	32	.	.	PUNCT
bjp-81605	242	1	caspases	caspase	NOUN
bjp-81605	242	2	are	be	AUX
bjp-81605	242	3	cellular	cellular	ADJ
bjp-81605	242	4	substrates	substrate	NOUN
bjp-81605	242	5	that	that	PRON
bjp-81605	242	6	include	include	VERB
bjp-81605	242	7	the	the	DET
bjp-81605	242	8	cytoplasm	cytoplasm	NOUN
bjp-81605	242	9	and	and	CCONJ
bjp-81605	242	10	nucleus	nucleus	NOUN
bjp-81605	242	11	,	,	PUNCT
bjp-81605	242	12	which	which	PRON
bjp-81605	242	13	are	be	AUX
bjp-81605	242	14	essential	essential	ADJ
bjp-81605	242	15	for	for	ADP
bjp-81605	242	16	structural	structural	ADJ
bjp-81605	242	17	elements	element	NOUN
bjp-81605	242	18	as	as	ADV
bjp-81605	242	19	well	well	ADV
bjp-81605	242	20	as	as	ADP
bjp-81605	242	21	elements	element	NOUN
bjp-81605	242	22	of	of	ADP
bjp-81605	242	23	the	the	DET
bjp-81605	242	24	dna	dna	PROPN
bjp-81605	242	25	repair	repair	NOUN
bjp-81605	242	26	mechanism	mechanism	NOUN
bjp-81605	242	27	,	,	PUNCT
bjp-81605	242	28	such	such	ADJ
bjp-81605	242	29	as	as	ADP
bjp-81605	242	30	protein	protein	NOUN
bjp-81605	242	31	kinase	kinase	NOUN
bjp-81605	242	32	and	and	CCONJ
bjp-81605	242	33	parp	parp	PROPN
bjp-81605	242	34	(	(	PUNCT
bjp-81605	242	35	pravdic	pravdic	ADJ
bjp-81605	242	36	,	,	PUNCT
bjp-81605	242	37	2023	2023	NUM
bjp-81605	242	38	;	;	PUNCT
bjp-81605	242	39	cingeetham	cingeetham	PROPN
bjp-81605	242	40	et	et	PROPN
bjp-81605	242	41	al	al	PROPN
bjp-81605	242	42	.	.	PROPN
bjp-81605	242	43	,	,	PUNCT
bjp-81605	242	44	2015	2015	NUM
bjp-81605	242	45	)	)	PUNCT
bjp-81605	242	46	.	.	PUNCT
bjp-81605	243	1	in	in	ADP
bjp-81605	243	2	the	the	DET
bjp-81605	243	3	present	present	ADJ
bjp-81605	243	4	study	study	NOUN
bjp-81605	243	5	,	,	PUNCT
bjp-81605	243	6	crt2	crt2	PROPN
bjp-81605	243	7	therapy	therapy	NOUN
bjp-81605	243	8	induced	induce	VERB
bjp-81605	243	9	significant	significant	ADJ
bjp-81605	243	10	caspase-3	caspase-3	NUM
bjp-81605	243	11	activation	activation	NOUN
bjp-81605	243	12	and	and	CCONJ
bjp-81605	243	13	simultaneous	simultaneous	ADJ
bjp-81605	243	14	parp	parp	ADJ
bjp-81605	243	15	cleavage	cleavage	NOUN
bjp-81605	243	16	in	in	ADP
bjp-81605	243	17	crc	crc	NOUN
bjp-81605	243	18	cells	cell	NOUN
bjp-81605	243	19	.	.	PUNCT
bjp-81605	244	1	these	these	DET
bjp-81605	244	2	mapks	mapks	NOUN
bjp-81605	244	3	mediate	mediate	NOUN
bjp-81605	244	4	cell	cell	NOUN
bjp-81605	244	5	survival	survival	NOUN
bjp-81605	244	6	and	and	CCONJ
bjp-81605	244	7	proliferation	proliferation	NOUN
bjp-81605	244	8	by	by	ADP
bjp-81605	244	9	phosphorylating	phosphorylate	VERB
bjp-81605	244	10	various	various	ADJ
bjp-81605	244	11	cellular	cellular	ADJ
bjp-81605	244	12	substrates	substrate	NOUN
bjp-81605	244	13	.	.	PUNCT
bjp-81605	245	1	moreover	moreover	ADV
bjp-81605	245	2	,	,	PUNCT
bjp-81605	245	3	crt2	crt2	PROPN
bjp-81605	245	4	therapy	therapy	NOUN
bjp-81605	245	5	increased	increase	VERB
bjp-81605	245	6	the	the	DET
bjp-81605	245	7	expression	expression	NOUN
bjp-81605	245	8	of	of	ADP
bjp-81605	245	9	p21	p21	NOUN
bjp-81605	245	10	and	and	CCONJ
bjp-81605	245	11	decreased	decrease	VERB
bjp-81605	245	12	that	that	PRON
bjp-81605	245	13	of	of	ADP
bjp-81605	245	14	cyclin	cyclin	NOUN
bjp-81605	245	15	d1	d1	PROPN
bjp-81605	245	16	,	,	PUNCT
bjp-81605	245	17	both	both	PRON
bjp-81605	245	18	of	of	ADP
bjp-81605	245	19	which	which	PRON
bjp-81605	245	20	are	be	AUX
bjp-81605	245	21	necessary	necessary	ADJ
bjp-81605	245	22	for	for	ADP
bjp-81605	245	23	cell	cell	NOUN
bjp-81605	245	24	proliferation	proliferation	NOUN
bjp-81605	245	25	.	.	PUNCT
bjp-81605	246	1	g1	g1	PROPN
bjp-81605	246	2	/	/	SYM
bjp-81605	246	3	s	s	PART
bjp-81605	246	4	phase	phase	NOUN
bjp-81605	246	5	cell	cell	NOUN
bjp-81605	246	6	cycle	cycle	NOUN
bjp-81605	246	7	arrest	arrest	NOUN
bjp-81605	246	8	was	be	AUX
bjp-81605	246	9	inhibited	inhibit	VERB
bjp-81605	246	10	by	by	ADP
bjp-81605	246	11	crt2	crt2	PROPN
bjp-81605	246	12	treatment	treatment	NOUN
bjp-81605	246	13	.	.	PUNCT
bjp-81605	247	1	in	in	ADP
bjp-81605	247	2	addition	addition	NOUN
bjp-81605	247	3	,	,	PUNCT
bjp-81605	247	4	vascular	vascular	ADJ
bjp-81605	247	5	endothelial	endothelial	ADJ
bjp-81605	247	6	growth	growth	NOUN
bjp-81605	247	7	factor	factor	NOUN
bjp-81605	247	8	receptor-1	receptor-1	NUM
bjp-81605	247	9	(	(	PUNCT
bjp-81605	247	10	vegfr1	vegfr1	NOUN
bjp-81605	247	11	)	)	PUNCT
bjp-81605	247	12	interacts	interact	VERB
bjp-81605	247	13	with	with	ADP
bjp-81605	247	14	its	its	PRON
bjp-81605	247	15	ligands	ligand	NOUN
bjp-81605	247	16	,	,	PUNCT
bjp-81605	247	17	vegf	vegf	PROPN
bjp-81605	247	18	-	-	PUNCT
bjp-81605	247	19	a	a	PROPN
bjp-81605	247	20	or	or	CCONJ
bjp-81605	247	21	vegf	vegf	PROPN
bjp-81605	247	22	-	-	PUNCT
bjp-81605	247	23	b	b	PROPN
bjp-81605	247	24	,	,	PUNCT
bjp-81605	247	25	to	to	PART
bjp-81605	247	26	activate	activate	VERB
bjp-81605	247	27	cellular	cellular	ADJ
bjp-81605	247	28	phenotypic	phenotypic	ADJ
bjp-81605	247	29	modification	modification	NOUN
bjp-81605	247	30	associated	associate	VERB
bjp-81605	247	31	with	with	ADP
bjp-81605	247	32	tumor	tumor	NOUN
bjp-81605	247	33	progression	progression	NOUN
bjp-81605	247	34	and	and	CCONJ
bjp-81605	247	35	invasion	invasion	NOUN
bjp-81605	247	36	(	(	PUNCT
bjp-81605	247	37	jin	jin	NOUN
bjp-81605	247	38	et	et	PROPN
bjp-81605	247	39	al	al	PROPN
bjp-81605	247	40	.	.	PROPN
bjp-81605	247	41	,	,	PUNCT
bjp-81605	247	42	2020	2020	NUM
bjp-81605	247	43	)	)	PUNCT
bjp-81605	247	44	.	.	PUNCT
bjp-81605	248	1	the	the	DET
bjp-81605	248	2	activation	activation	NOUN
bjp-81605	248	3	of	of	ADP
bjp-81605	248	4	downstream	downstream	ADJ
bjp-81605	248	5	signaling	signal	VERB
bjp-81605	248	6	pathways	pathway	NOUN
bjp-81605	248	7	of	of	ADP
bjp-81605	248	8	jnk/1	jnk/1	PROPN
bjp-81605	248	9	,	,	PUNCT
bjp-81605	248	10	erk-1/2	erk-1/2	PROPN
bjp-81605	248	11	,	,	PUNCT
bjp-81605	248	12	and	and	CCONJ
bjp-81605	248	13	mapk	mapk	NOUN
bjp-81605	248	14	primes	prime	NOUN
bjp-81605	248	15	cell	cell	NOUN
bjp-81605	248	16	proliferation	proliferation	NOUN
bjp-81605	248	17	,	,	PUNCT
bjp-81605	248	18	migration	migration	NOUN
bjp-81605	248	19	,	,	PUNCT
bjp-81605	248	20	and	and	CCONJ
bjp-81605	248	21	metastasis	metastasis	NOUN
bjp-81605	248	22	.	.	PUNCT
bjp-81605	249	1	current	current	ADJ
bjp-81605	249	2	crt2	crt2	PROPN
bjp-81605	249	3	treatments	treatment	NOUN
bjp-81605	249	4	significantly	significantly	ADV
bjp-81605	249	5	affect	affect	VERB
bjp-81605	249	6	jnk1/2	jnk1/2	PROPN
bjp-81605	249	7	and	and	CCONJ
bjp-81605	249	8	erk1/2	erk1/2	PROPN
bjp-81605	249	9	phosphorylation	phosphorylation	NOUN
bjp-81605	249	10	protein	protein	NOUN
bjp-81605	249	11	expression	expression	NOUN
bjp-81605	249	12	in	in	ADP
bjp-81605	249	13	crc	crc	NOUN
bjp-81605	249	14	cells	cell	NOUN
bjp-81605	249	15	by	by	ADP
bjp-81605	249	16	1.21	1.21	NUM
bjp-81605	249	17	and	and	CCONJ
bjp-81605	249	18	1.5	1.5	NUM
bjp-81605	249	19	folds	fold	NOUN
bjp-81605	249	20	.	.	PUNCT
bjp-81605	250	1	these	these	DET
bjp-81605	250	2	findings	finding	NOUN
bjp-81605	250	3	suggest	suggest	VERB
bjp-81605	250	4	crt2	crt2	PROPN
bjp-81605	250	5	inhibits	inhibit	VERB
bjp-81605	250	6	vegfr1	vegfr1	NOUN
bjp-81605	250	7	-	-	PUNCT
bjp-81605	250	8	persuaded	persuade	VERB
bjp-81605	250	9	activations	activation	NOUN
bjp-81605	250	10	.	.	PUNCT
bjp-81605	251	1	a	a	DET
bjp-81605	251	2	study	study	NOUN
bjp-81605	251	3	shows	show	VERB
bjp-81605	251	4	that	that	SCONJ
bjp-81605	251	5	a	a	DET
bjp-81605	251	6	peptide	peptide	NOUN
bjp-81605	251	7	isolated	isolate	VERB
bjp-81605	251	8	from	from	ADP
bjp-81605	251	9	garlic	garlic	ADJ
bjp-81605	251	10	(	(	PUNCT
bjp-81605	251	11	vs9	vs9	NOUN
bjp-81605	251	12	)	)	PUNCT
bjp-81605	251	13	exhibited	exhibit	VERB
bjp-81605	251	14	an	an	DET
bjp-81605	251	15	anti	anti	ADJ
bjp-81605	251	16	-	-	ADJ
bjp-81605	251	17	cancer	cancer	ADJ
bjp-81605	251	18	effect	effect	NOUN
bjp-81605	251	19	against	against	ADP
bjp-81605	251	20	leukemic	leukemic	ADJ
bjp-81605	251	21	and	and	CCONJ
bjp-81605	251	22	ht	ht	PROPN
bjp-81605	251	23	-116	-116	PROPN
bjp-81605	251	24	cell	cell	NOUN
bjp-81605	251	25	lines	line	NOUN
bjp-81605	251	26	via	via	ADP
bjp-81605	251	27	interaction	interaction	NOUN
bjp-81605	251	28	with	with	ADP
bjp-81605	251	29	bcl-2	bcl-2	VERB
bjp-81605	251	30	family	family	NOUN
bjp-81605	251	31	proteins	protein	NOUN
bjp-81605	251	32	(	(	PUNCT
bjp-81605	251	33	rasaratnam	rasaratnam	X
bjp-81605	251	34	et	et	PROPN
bjp-81605	251	35	al	al	PROPN
bjp-81605	251	36	.	.	PROPN
bjp-81605	251	37	,	,	PUNCT
bjp-81605	251	38	2021	2021	NUM
bjp-81605	251	39	)	)	PUNCT
bjp-81605	251	40	.	.	PUNCT
bjp-81605	252	1	here	here	ADV
bjp-81605	252	2	,	,	PUNCT
bjp-81605	252	3	this	this	DET
bjp-81605	252	4	study	study	NOUN
bjp-81605	252	5	first	first	ADV
bjp-81605	252	6	evaluates	evaluate	VERB
bjp-81605	252	7	the	the	DET
bjp-81605	252	8	effects	effect	NOUN
bjp-81605	252	9	of	of	ADP
bjp-81605	252	10	crt2	crt2	PROPN
bjp-81605	252	11	on	on	ADP
bjp-81605	252	12	the	the	DET
bjp-81605	252	13	identity	identity	NOUN
bjp-81605	252	14	compound	compound	NOUN
bjp-81605	252	15	,	,	PUNCT
bjp-81605	252	16	which	which	PRON
bjp-81605	252	17	exhibited	exhibit	VERB
bjp-81605	252	18	specific	specific	ADJ
bjp-81605	252	19	cytotoxic	cytotoxic	ADJ
bjp-81605	252	20	activity	activity	NOUN
bjp-81605	252	21	in	in	ADP
bjp-81605	252	22	ht-116	ht-116	PROPN
bjp-81605	252	23	cells	cell	NOUN
bjp-81605	252	24	,	,	PUNCT
bjp-81605	252	25	and	and	CCONJ
bjp-81605	252	26	initiated	initiate	VERB
bjp-81605	252	27	cell	cell	NOUN
bjp-81605	252	28	apoptosis	apoptosis	NOUN
bjp-81605	252	29	and	and	CCONJ
bjp-81605	252	30	cell	cell	NOUN
bjp-81605	252	31	cycle	cycle	NOUN
bjp-81605	252	32	arrest	arrest	NOUN
bjp-81605	252	33	in	in	ADP
bjp-81605	252	34	a	a	DET
bjp-81605	252	35	dose	dose	NOUN
bjp-81605	252	36	and	and	CCONJ
bjp-81605	252	37	time	time	NOUN
bjp-81605	252	38	-	-	PUNCT
bjp-81605	252	39	dependent	dependent	ADJ
bjp-81605	252	40	manner	manner	NOUN
bjp-81605	252	41	.	.	PUNCT
bjp-81605	253	1	second	second	ADJ
bjp-81605	253	2	,	,	PUNCT
bjp-81605	253	3	crt2	crt2	PROPN
bjp-81605	253	4	inhibited	inhibit	VERB
bjp-81605	253	5	the	the	DET
bjp-81605	253	6	protein	protein	NOUN
bjp-81605	253	7	expression	expression	NOUN
bjp-81605	253	8	of	of	ADP
bjp-81605	253	9	pi3k	pi3k	PROPN
bjp-81605	253	10	and	and	CCONJ
bjp-81605	253	11	akt	akt	PROPN
bjp-81605	253	12	at	at	ADP
bjp-81605	253	13	the	the	DET
bjp-81605	253	14	posttranslational	posttranslational	ADJ
bjp-81605	253	15	levels	level	NOUN
bjp-81605	253	16	and	and	CCONJ
bjp-81605	253	17	reduced	reduce	VERB
bjp-81605	253	18	the	the	DET
bjp-81605	253	19	levels	level	NOUN
bjp-81605	253	20	of	of	ADP
bjp-81605	253	21	erk/1	erk/1	PROPN
bjp-81605	253	22	and	and	CCONJ
bjp-81605	253	23	jnk1	jnk1	PROPN
bjp-81605	253	24	.	.	PUNCT
bjp-81605	254	1	finally	finally	ADV
bjp-81605	254	2	,	,	PUNCT
bjp-81605	254	3	crt2	crt2	PROPN
bjp-81605	254	4	was	be	AUX
bjp-81605	254	5	inhibited	inhibit	VERB
bjp-81605	254	6	by	by	ADP
bjp-81605	254	7	vegfr1	vegfr1	NOUN
bjp-81605	254	8	%	%	NOUN
bjp-81605	254	9	r	r	NOUN
bjp-81605	254	10	e	e	NOUN
bjp-81605	254	11	la	la	X
bjp-81605	254	12	ti	ti	X
bjp-81605	254	13	v	v	ADP
bjp-81605	254	14	e	e	X
bjp-81605	254	15	p	p	X
bjp-81605	254	16	ro	ro	X
bjp-81605	254	17	te	te	PROPN
bjp-81605	254	18	in	in	ADP
bjp-81605	254	19	e	e	X
bjp-81605	254	20	x	x	X
bjp-81605	254	21	p	p	X
bjp-81605	254	22	re	re	ADP
bjp-81605	254	23	s	s	PROPN
bjp-81605	254	24	s	s	X
bjp-81605	254	25	io	io	PROPN
bjp-81605	254	26	n	n	PROPN
bjp-81605	254	27	2.5	2.5	NUM
bjp-81605	254	28	2.0	2.0	NUM
bjp-81605	254	29	1.5	1.5	NUM
bjp-81605	254	30	1.0	1.0	NUM
bjp-81605	254	31	0.5	0.5	NUM
bjp-81605	254	32	0	0	NUM
bjp-81605	254	33	0	0	NUM
bjp-81605	254	34	10	10	NUM
bjp-81605	254	35	20	20	NUM
bjp-81605	254	36	figure	figure	NOUN
bjp-81605	254	37	9	9	NUM
bjp-81605	254	38	:	:	PUNCT
bjp-81605	254	39	western	western	ADJ
bjp-81605	254	40	blot	blot	NOUN
bjp-81605	254	41	analysis	analysis	NOUN
bjp-81605	254	42	showing	show	VERB
bjp-81605	254	43	the	the	DET
bjp-81605	254	44	effect	effect	NOUN
bjp-81605	254	45	of	of	ADP
bjp-81605	254	46	crt2	crt2	PROPN
bjp-81605	254	47	on	on	ADP
bjp-81605	254	48	the	the	DET
bjp-81605	254	49	expression	expression	NOUN
bjp-81605	254	50	of	of	ADP
bjp-81605	254	51	p	p	PROPN
bjp-81605	254	52	-	-	PUNCT
bjp-81605	254	53	mek	mek	NOUN
bjp-81605	254	54	,	,	PUNCT
bjp-81605	254	55	p	p	PROPN
bjp-81605	254	56	-	-	PUNCT
bjp-81605	254	57	erk1/2	erk1/2	NOUN
bjp-81605	254	58	,	,	PUNCT
bjp-81605	254	59	and	and	CCONJ
bjp-81605	254	60	p	p	X
bjp-81605	254	61	-	-	PUNCT
bjp-81605	254	62	akt	akt	NOUN
bjp-81605	254	63	in	in	ADP
bjp-81605	254	64	ht116	ht116	PROPN
bjp-81605	254	65	colorectal	colorectal	ADJ
bjp-81605	254	66	cancer	cancer	NOUN
bjp-81605	254	67	cells	cell	NOUN
bjp-81605	254	68	(	(	PUNCT
bjp-81605	254	69	a	a	NOUN
bjp-81605	254	70	)	)	PUNCT
bjp-81605	254	71	.	.	PUNCT
bjp-81605	255	1	densitometric	densitometric	ADJ
bjp-81605	255	2	quantification	quantification	NOUN
bjp-81605	255	3	of	of	ADP
bjp-81605	255	4	p	p	PROPN
bjp-81605	255	5	-	-	PUNCT
bjp-81605	255	6	mek	mek	NOUN
bjp-81605	255	7	,	,	PUNCT
bjp-81605	255	8	p	p	PROPN
bjp-81605	255	9	-	-	PUNCT
bjp-81605	255	10	erk1/2	erk1/2	NOUN
bjp-81605	255	11	,	,	PUNCT
bjp-81605	255	12	and	and	CCONJ
bjp-81605	255	13	p	p	X
bjp-81605	255	14	-	-	PUNCT
bjp-81605	255	15	akt	akt	PROPN
bjp-81605	255	16	levels	level	NOUN
bjp-81605	255	17	normalized	normalize	VERB
bjp-81605	255	18	to	to	ADP
bjp-81605	255	19	βactin	βactin	PROPN
bjp-81605	255	20	(	(	PUNCT
bjp-81605	255	21	b	b	NOUN
bjp-81605	255	22	)	)	PUNCT
bjp-81605	255	23	.	.	PUNCT
bjp-81605	256	1	data	datum	NOUN
bjp-81605	256	2	were	be	AUX
bjp-81605	256	3	presented	present	VERB
bjp-81605	256	4	as	as	ADP
bjp-81605	256	5	mean	mean	NOUN
bjp-81605	256	6	 	 	SPACE
bjp-81605	256	7	±	±	NOUN
bjp-81605	256	8	 	 	SPACE
bjp-81605	256	9	sem	sem	NOUN
bjp-81605	256	10	;	;	PUNCT
bjp-81605	256	11	n=5	n=5	NUM
bjp-81605	256	12	;	;	PUNCT
bjp-81605	256	13	ap<0.05	ap<0.05	NOUN
bjp-81605	256	14	;	;	PUNCT
bjp-81605	256	15	bp<0.01	bp<0.01	NOUN
bjp-81605	256	16	;	;	PUNCT
bjp-81605	256	17	cp<0.0001	cp<0.0001	PROPN
bjp-81605	256	18	vs.	vs.	ADP
bjp-81605	256	19	control	control	NOUN
bjp-81605	256	20	crt2	crt2	PROPN
bjp-81605	256	21	concentration	concentration	NOUN
bjp-81605	256	22	(	(	PUNCT
bjp-81605	256	23	µm	µm	NOUN
bjp-81605	256	24	)	)	PUNCT
bjp-81605	256	25	85	85	NUM
bjp-81605	256	26	kda	kda	NOUN
bjp-81605	256	27	56	56	NUM
bjp-81605	257	1	kda	kda	NOUN
bjp-81605	257	2	43	43	NUM
bjp-81605	257	3	kda	kda	NOUN
bjp-81605	257	4	54	54	NUM
bjp-81605	257	5	kda	kda	NOUN
bjp-81605	257	6	39	39	NUM
bjp-81605	257	7	kda	kda	NOUN
bjp-81605	257	8	42	42	NUM
bjp-81605	257	9	kda	kda	NOUN
bjp-81605	257	10	pi3k	pi3k	PROPN
bjp-81605	257	11	p	p	PROPN
bjp-81605	257	12	-	-	PUNCT
bjp-81605	257	13	akt	akt	PROPN
bjp-81605	257	14	perk	perk	NOUN
bjp-81605	257	15	1/2	1/2	NUM
bjp-81605	257	16	p	p	PROPN
bjp-81605	257	17	-	-	PUNCT
bjp-81605	257	18	jnk	jnk	PROPN
bjp-81605	257	19	1/2	1/2	NUM
bjp-81605	257	20	p38	p38	NOUN
bjp-81605	257	21	β	β	NOUN
bjp-81605	257	22	-	-	NOUN
bjp-81605	257	23	actin	actin	NOUN
bjp-81605	257	24	b	b	PROPN
bjp-81605	257	25	a	a	DET
bjp-81605	257	26	control	control	NOUN
bjp-81605	257	27	10	10	NUM
bjp-81605	257	28	µm	µm	PART
bjp-81605	257	29	20	20	NUM
bjp-81605	257	30	µm	µm	ADP
bjp-81605	257	31	ns	ns	NUM
bjp-81605	257	32	b	b	PROPN
bjp-81605	257	33	c	c	PROPN
bjp-81605	257	34	b	b	PROPN
bjp-81605	257	35	c	c	PROPN
bjp-81605	257	36	b	b	PROPN
bjp-81605	257	37	a	a	DET
bjp-81605	257	38	a	a	PRON
bjp-81605	257	39	b	b	NOUN
bjp-81605	257	40	β	β	X
bjp-81605	257	41	-	-	PUNCT
bjp-81605	257	42	actin	actin	ADJ
bjp-81605	257	43	p38	p38	NOUN
bjp-81605	257	44	p	p	PROPN
bjp-81605	257	45	-	-	PUNCT
bjp-81605	257	46	jnk	jnk	PROPN
bjp-81605	257	47	1/2	1/2	NUM
bjp-81605	257	48	perk	perk	NOUN
bjp-81605	257	49	1/2	1/2	NUM
bjp-81605	257	50	p	p	NOUN
bjp-81605	257	51	-	-	PUNCT
bjp-81605	257	52	akt	akt	PROPN
bjp-81605	257	53	pi3k	pi3k	PROPN
bjp-81605	257	54	b	b	PROPN
bjp-81605	257	55	a	a	DET
bjp-81605	257	56	98	98	NUM
bjp-81605	257	57	bangladesh	bangladesh	NOUN
bjp-81605	257	58	j	j	PROPN
bjp-81605	257	59	pharmacol	pharmacol	PROPN
bjp-81605	257	60	2025	2025	NUM
bjp-81605	257	61	;	;	PUNCT
bjp-81605	257	62	20	20	NUM
bjp-81605	257	63	:	:	SYM
bjp-81605	257	64	89	89	NUM
bjp-81605	257	65	-	-	SYM
bjp-81605	257	66	100	100	NUM
bjp-81605	257	67	kinase	kinase	NOUN
bjp-81605	257	68	-	-	PUNCT
bjp-81605	257	69	induced	induce	VERB
bjp-81605	257	70	cell	cell	NOUN
bjp-81605	257	71	proliferation	proliferation	NOUN
bjp-81605	257	72	via	via	ADP
bjp-81605	257	73	pi3k	pi3k	PROPN
bjp-81605	257	74	/	/	SYM
bjp-81605	257	75	akt	akt	PROPN
bjp-81605	257	76	/	/	SYM
bjp-81605	257	77	erk1/	erk1/	PROPN
bjp-81605	257	78	jnk	jnk	PROPN
bjp-81605	257	79	signal	signal	PROPN
bjp-81605	257	80	transduction	transduction	NOUN
bjp-81605	257	81	in	in	ADP
bjp-81605	257	82	ht-116	ht-116	PROPN
bjp-81605	257	83	cells	cell	NOUN
bjp-81605	257	84	.	.	PUNCT
bjp-81605	258	1	a	a	DET
bjp-81605	258	2	primary	primary	ADJ
bjp-81605	258	3	limitation	limitation	NOUN
bjp-81605	258	4	of	of	ADP
bjp-81605	258	5	the	the	DET
bjp-81605	258	6	present	present	ADJ
bjp-81605	258	7	study	study	NOUN
bjp-81605	258	8	is	be	AUX
bjp-81605	258	9	its	its	PRON
bjp-81605	258	10	reliance	reliance	NOUN
bjp-81605	258	11	on	on	ADP
bjp-81605	258	12	in	in	ADP
bjp-81605	258	13	silico	silico	NOUN
bjp-81605	258	14	molecular	molecular	ADJ
bjp-81605	258	15	docking	docking	NOUN
bjp-81605	258	16	and	and	CCONJ
bjp-81605	258	17	in	in	ADP
bjp-81605	258	18	vitro	vitro	X
bjp-81605	258	19	assays	assay	NOUN
bjp-81605	258	20	using	use	VERB
bjp-81605	258	21	colorectal	colorectal	ADJ
bjp-81605	258	22	cancer	cancer	NOUN
bjp-81605	258	23	cell	cell	NOUN
bjp-81605	258	24	lines	line	NOUN
bjp-81605	258	25	(	(	PUNCT
bjp-81605	258	26	ht-116	ht-116	PROPN
bjp-81605	258	27	)	)	PUNCT
bjp-81605	258	28	.	.	PUNCT
bjp-81605	259	1	while	while	SCONJ
bjp-81605	259	2	these	these	DET
bjp-81605	259	3	approaches	approach	NOUN
bjp-81605	259	4	provide	provide	VERB
bjp-81605	259	5	valuable	valuable	ADJ
bjp-81605	259	6	preliminary	preliminary	ADJ
bjp-81605	259	7	insights	insight	NOUN
bjp-81605	259	8	,	,	PUNCT
bjp-81605	259	9	the	the	DET
bjp-81605	259	10	absence	absence	NOUN
bjp-81605	259	11	of	of	ADP
bjp-81605	259	12	in	in	ADP
bjp-81605	259	13	vivo	vivo	NOUN
bjp-81605	259	14	animal	animal	NOUN
bjp-81605	259	15	model	model	NOUN
bjp-81605	259	16	experiments	experiment	NOUN
bjp-81605	259	17	limits	limit	VERB
bjp-81605	259	18	the	the	DET
bjp-81605	259	19	ability	ability	NOUN
bjp-81605	259	20	to	to	PART
bjp-81605	259	21	evaluate	evaluate	VERB
bjp-81605	259	22	the	the	DET
bjp-81605	259	23	systemic	systemic	ADJ
bjp-81605	259	24	efficacy	efficacy	NOUN
bjp-81605	259	25	,	,	PUNCT
bjp-81605	259	26	bioavailability	bioavailability	NOUN
bjp-81605	259	27	,	,	PUNCT
bjp-81605	259	28	pharmacokinetics	pharmacokinetic	NOUN
bjp-81605	259	29	,	,	PUNCT
bjp-81605	259	30	and	and	CCONJ
bjp-81605	259	31	potential	potential	ADJ
bjp-81605	259	32	toxicity	toxicity	NOUN
bjp-81605	259	33	of	of	ADP
bjp-81605	259	34	crt2	crt2	PROPN
bjp-81605	259	35	under	under	ADP
bjp-81605	259	36	physiological	physiological	ADJ
bjp-81605	259	37	conditions	condition	NOUN
bjp-81605	259	38	.	.	PUNCT
bjp-81605	260	1	conclusion	conclusion	NOUN
bjp-81605	260	2	crt-2	crt-2	PUNCT
bjp-81605	260	3	peptide	peptide	NOUN
bjp-81605	260	4	constructs	construct	NOUN
bjp-81605	260	5	targeting	target	VERB
bjp-81605	260	6	the	the	DET
bjp-81605	260	7	vegfa/	vegfa/	NUM
bjp-81605	260	8	vegfr1	vegfr1	NOUN
bjp-81605	260	9	-	-	PUNCT
bjp-81605	260	10	binding	bind	VERB
bjp-81605	260	11	region	region	NOUN
bjp-81605	260	12	inhibited	inhibit	VERB
bjp-81605	260	13	proliferation	proliferation	NOUN
bjp-81605	260	14	and	and	CCONJ
bjp-81605	260	15	angiogenesis	angiogenesis	NOUN
bjp-81605	260	16	in	in	ADP
bjp-81605	260	17	vegfr1	vegfr1	NOUN
bjp-81605	260	18	-	-	PUNCT
bjp-81605	260	19	positive	positive	ADJ
bjp-81605	260	20	hct-116	hct-116	NOUN
bjp-81605	260	21	cells	cell	NOUN
bjp-81605	260	22	by	by	ADP
bjp-81605	260	23	suppressing	suppress	VERB
bjp-81605	260	24	vegfr1	vegfr1	NOUN
bjp-81605	260	25	,	,	PUNCT
bjp-81605	260	26	pi3k	pi3k	PROPN
bjp-81605	260	27	,	,	PUNCT
bjp-81605	260	28	and	and	CCONJ
bjp-81605	260	29	erk1/2	erk1/2	PROPN
bjp-81605	260	30	signaling	signal	VERB
bjp-81605	260	31	.	.	PUNCT
bjp-81605	261	1	apoptosis	apoptosis	NOUN
bjp-81605	261	2	was	be	AUX
bjp-81605	261	3	enhanced	enhance	VERB
bjp-81605	261	4	via	via	ADP
bjp-81605	261	5	p58	p58	NOUN
bjp-81605	261	6	upregulation	upregulation	NOUN
bjp-81605	261	7	and	and	CCONJ
bjp-81605	261	8	bcl2	bcl2	NOUN
bjp-81605	261	9	downregulation	downregulation	NOUN
bjp-81605	261	10	,	,	PUNCT
bjp-81605	261	11	indicating	indicate	VERB
bjp-81605	261	12	crt2	crt2	PROPN
bjp-81605	261	13	's	's	PART
bjp-81605	261	14	potential	potential	NOUN
bjp-81605	261	15	as	as	ADP
bjp-81605	261	16	a	a	DET
bjp-81605	261	17	promising	promising	ADJ
bjp-81605	261	18	therapeutic	therapeutic	ADJ
bjp-81605	261	19	agent	agent	NOUN
bjp-81605	261	20	for	for	ADP
bjp-81605	261	21	cancer	cancer	NOUN
bjp-81605	261	22	treatment	treatment	NOUN
bjp-81605	261	23	.	.	PUNCT
bjp-81605	262	1	financial	financial	ADJ
bjp-81605	262	2	support	support	NOUN
bjp-81605	262	3	self	self	NOUN
bjp-81605	262	4	-	-	PUNCT
bjp-81605	262	5	funded	fund	VERB
bjp-81605	262	6	ethical	ethical	ADJ
bjp-81605	262	7	issue	issue	NOUN
bjp-81605	262	8	the	the	DET
bjp-81605	262	9	guidelines	guideline	NOUN
bjp-81605	262	10	about	about	ADP
bjp-81605	262	11	the	the	DET
bjp-81605	262	12	development	development	NOUN
bjp-81605	262	13	,	,	PUNCT
bjp-81605	262	14	acquisition	acquisition	NOUN
bjp-81605	262	15	,	,	PUNCT
bjp-81605	262	16	authentication	authentication	NOUN
bjp-81605	262	17	,	,	PUNCT
bjp-81605	262	18	cryopreservation	cryopreservation	NOUN
bjp-81605	262	19	,	,	PUNCT
bjp-81605	262	20	and	and	CCONJ
bjp-81605	262	21	transfer	transfer	NOUN
bjp-81605	262	22	of	of	ADP
bjp-81605	262	23	cell	cell	NOUN
bjp-81605	262	24	lines	line	NOUN
bjp-81605	262	25	between	between	ADP
bjp-81605	262	26	laboratories	laboratory	NOUN
bjp-81605	262	27	were	be	AUX
bjp-81605	262	28	strictly	strictly	ADV
bjp-81605	262	29	followed	follow	VERB
bjp-81605	262	30	.	.	PUNCT
bjp-81605	263	1	besides	besides	SCONJ
bjp-81605	263	2	,	,	PUNCT
bjp-81605	263	3	microbial	microbial	ADJ
bjp-81605	263	4	contamination	contamination	NOUN
bjp-81605	263	5	(	(	PUNCT
bjp-81605	263	6	commonly	commonly	ADV
bjp-81605	263	7	mycoplasma	mycoplasma	NOUN
bjp-81605	263	8	)	)	PUNCT
bjp-81605	263	9	,	,	PUNCT
bjp-81605	263	10	characterization	characterization	NOUN
bjp-81605	263	11	,	,	PUNCT
bjp-81605	263	12	instability	instability	NOUN
bjp-81605	263	13	,	,	PUNCT
bjp-81605	263	14	and	and	CCONJ
bjp-81605	263	15	misidentification	misidentification	NOUN
bjp-81605	263	16	was	be	AUX
bjp-81605	263	17	considered	consider	VERB
bjp-81605	263	18	seriously	seriously	ADV
bjp-81605	263	19	.	.	PUNCT
bjp-81605	264	1	conflict	conflict	NOUN
bjp-81605	264	2	of	of	ADP
bjp-81605	264	3	interest	interest	NOUN
bjp-81605	264	4	authors	author	NOUN
bjp-81605	264	5	declare	declare	VERB
bjp-81605	264	6	no	no	DET
bjp-81605	264	7	conflict	conflict	NOUN
bjp-81605	264	8	of	of	ADP
bjp-81605	264	9	interest	interest	NOUN
bjp-81605	264	10	acknowledgement	acknowledgement	NOUN
bjp-81605	264	11	authors	author	NOUN
bjp-81605	264	12	would	would	AUX
bjp-81605	264	13	like	like	VERB
bjp-81605	264	14	to	to	PART
bjp-81605	264	15	thank	thank	VERB
bjp-81605	264	16	p.	p.	PROPN
bjp-81605	264	17	s.	s.	PROPN
bjp-81605	265	1	g.	g.	PROPN
bjp-81605	265	2	son	son	PROPN
bjp-81605	265	3	’s	’s	PART
bjp-81605	265	4	and	and	CCONJ
bjp-81605	265	5	charity	charity	NOUN
bjp-81605	265	6	and	and	CCONJ
bjp-81605	265	7	tamil	tamil	PROPN
bjp-81605	265	8	nadu	nadu	PROPN
bjp-81605	265	9	dr	dr	PROPN
bjp-81605	265	10	.	.	PROPN
bjp-81605	265	11	m.	m.	PROPN
bjp-81605	265	12	g.	g.	PROPN
bjp-81605	265	13	r.	r.	PROPN
bjp-81605	265	14	medical	medical	PROPN
bjp-81605	265	15	university	university	PROPN
bjp-81605	265	16	chennai	chennai	NOUN
bjp-81605	265	17	for	for	ADP
bjp-81605	265	18	providing	provide	VERB
bjp-81605	265	19	us	we	PRON
bjp-81605	265	20	with	with	ADP
bjp-81605	265	21	a	a	DET
bjp-81605	265	22	better	well	ADJ
bjp-81605	265	23	facility	facility	NOUN
bjp-81605	265	24	and	and	CCONJ
bjp-81605	265	25	environment	environment	NOUN
bjp-81605	265	26	to	to	ADP
bjp-81605	265	27	this	this	DET
bjp-81605	265	28	study	study	NOUN
bjp-81605	265	29	references	reference	NOUN
bjp-81605	265	30	ahmed	ahmed	PROPN
bjp-81605	265	31	ag	ag	PROPN
bjp-81605	265	32	,	,	PUNCT
bjp-81605	265	33	hussein	hussein	PROPN
bjp-81605	265	34	uk	uk	PROPN
bjp-81605	265	35	,	,	PUNCT
bjp-81605	265	36	ahmed	ahmed	PROPN
bjp-81605	265	37	ae	ae	PROPN
bjp-81605	265	38	,	,	PUNCT
bjp-81605	265	39	kim	kim	PROPN
bjp-81605	265	40	km	km	PROPN
bjp-81605	265	41	,	,	PUNCT
bjp-81605	265	42	mahmoud	mahmoud	PROPN
bjp-81605	265	43	hm	hm	PROPN
bjp-81605	265	44	,	,	PUNCT
bjp-81605	265	45	hammouda	hammouda	NOUN
bjp-81605	265	46	o.	o.	PROPN
bjp-81605	265	47	mustard	mustard	NOUN
bjp-81605	265	48	seed	seed	NOUN
bjp-81605	265	49	(	(	PUNCT
bjp-81605	265	50	brassica	brassica	NOUN
bjp-81605	265	51	nigra	nigra	NOUN
bjp-81605	265	52	)	)	PUNCT
bjp-81605	265	53	extract	extract	VERB
bjp-81605	265	54	exhibits	exhibit	VERB
bjp-81605	265	55	antiproliferative	antiproliferative	ADJ
bjp-81605	265	56	effect	effect	NOUN
bjp-81605	265	57	against	against	ADP
bjp-81605	265	58	human	human	ADJ
bjp-81605	265	59	lung	lung	NOUN
bjp-81605	265	60	cancer	cancer	NOUN
bjp-81605	265	61	cells	cell	NOUN
bjp-81605	265	62	through	through	ADP
bjp-81605	265	63	differential	differential	ADJ
bjp-81605	265	64	regulation	regulation	NOUN
bjp-81605	265	65	of	of	ADP
bjp-81605	265	66	apoptosis	apoptosis	NOUN
bjp-81605	265	67	,	,	PUNCT
bjp-81605	265	68	cell	cell	NOUN
bjp-81605	265	69	cycle	cycle	NOUN
bjp-81605	265	70	,	,	PUNCT
bjp-81605	265	71	migration	migration	NOUN
bjp-81605	265	72	,	,	PUNCT
bjp-81605	265	73	and	and	CCONJ
bjp-81605	265	74	invasion	invasion	NOUN
bjp-81605	265	75	.	.	PUNCT
bjp-81605	266	1	molecules	molecule	NOUN
bjp-81605	266	2	2020	2020	NUM
bjp-81605	266	3	;	;	PUNCT
bjp-81605	266	4	25	25	NUM
bjp-81605	266	5	:	:	SYM
bjp-81605	266	6	2069	2069	NUM
bjp-81605	266	7	.	.	PUNCT
bjp-81605	267	1	ara	ara	PROPN
bjp-81605	267	2	mst	mst	PROPN
bjp-81605	267	3	n	n	PROPN
bjp-81605	267	4	,	,	PUNCT
bjp-81605	267	5	hyodo	hyodo	NOUN
bjp-81605	267	6	m	m	PROPN
bjp-81605	267	7	,	,	PUNCT
bjp-81605	267	8	ohga	ohga	PROPN
bjp-81605	267	9	n	n	CCONJ
bjp-81605	267	10	,	,	PUNCT
bjp-81605	267	11	hida	hida	PROPN
bjp-81605	267	12	k	k	PROPN
bjp-81605	267	13	,	,	PUNCT
bjp-81605	267	14	harashima	harashima	PROPN
bjp-81605	267	15	h.	h.	PROPN
bjp-81605	267	16	development	development	NOUN
bjp-81605	267	17	of	of	ADP
bjp-81605	267	18	a	a	DET
bjp-81605	267	19	novel	novel	ADJ
bjp-81605	267	20	dna	dna	NOUN
bjp-81605	267	21	aptamer	aptamer	NOUN
bjp-81605	267	22	ligand	ligand	NOUN
bjp-81605	267	23	targeting	target	VERB
bjp-81605	267	24	to	to	ADP
bjp-81605	267	25	primary	primary	ADJ
bjp-81605	267	26	cultured	cultured	ADJ
bjp-81605	267	27	tumor	tumor	NOUN
bjp-81605	267	28	endothelial	endothelial	NOUN
bjp-81605	267	29	cells	cell	NOUN
bjp-81605	267	30	by	by	ADP
bjp-81605	267	31	a	a	DET
bjp-81605	267	32	cell	cell	NOUN
bjp-81605	267	33	-	-	PUNCT
bjp-81605	267	34	based	base	VERB
bjp-81605	267	35	selex	selex	PROPN
bjp-81605	267	36	method	method	NOUN
bjp-81605	267	37	.	.	PUNCT
bjp-81605	268	1	plos	plos	PROPN
bjp-81605	268	2	one	one	NUM
bjp-81605	268	3	.	.	PUNCT
bjp-81605	268	4	2012	2012	NUM
bjp-81605	268	5	;	;	PUNCT
bjp-81605	268	6	7	7	NUM
bjp-81605	268	7	:	:	SYM
bjp-81605	268	8	50	50	NUM
bjp-81605	268	9	-	-	SYM
bjp-81605	268	10	74	74	NUM
bjp-81605	268	11	.	.	PUNCT
bjp-81605	269	1	baidoun	baidoun	NOUN
bjp-81605	269	2	,	,	PUNCT
bjp-81605	269	3	f	f	X
bjp-81605	269	4	,	,	PUNCT
bjp-81605	269	5	elshiwy	elshiwy	PROPN
bjp-81605	269	6	k	k	PROPN
bjp-81605	269	7	,	,	PUNCT
bjp-81605	269	8	elkeraie	elkeraie	PROPN
bjp-81605	269	9	y	y	PROPN
bjp-81605	269	10	,	,	PUNCT
bjp-81605	269	11	merjaneh	merjaneh	PROPN
bjp-81605	270	1	z	z	PROPN
bjp-81605	270	2	,	,	PUNCT
bjp-81605	270	3	khoudari	khoudari	PROPN
bjp-81605	270	4	g	g	PROPN
bjp-81605	270	5	,	,	PUNCT
bjp-81605	270	6	sarmini	sarmini	NOUN
bjp-81605	270	7	,	,	PUNCT
bjp-81605	270	8	m	m	PROPN
bjp-81605	270	9	t	t	PROPN
bjp-81605	270	10	,	,	PUNCT
bjp-81605	270	11	gad	gad	PROPN
bjp-81605	270	12	m	m	PROPN
bjp-81605	270	13	,	,	PUNCT
bjp-81605	270	14	al	al	PROPN
bjp-81605	270	15	-	-	PUNCT
bjp-81605	270	16	husseini	husseini	PROPN
bjp-81605	270	17	m	m	PROPN
bjp-81605	270	18	,	,	PUNCT
bjp-81605	270	19	saad	saad	PROPN
bjp-81605	270	20	a.	a.	PROPN
bjp-81605	270	21	colorectal	colorectal	PROPN
bjp-81605	270	22	cancer	cancer	NOUN
bjp-81605	270	23	epidemiology	epidemiology	NOUN
bjp-81605	270	24	:	:	PUNCT
bjp-81605	270	25	recent	recent	ADJ
bjp-81605	270	26	trends	trend	NOUN
bjp-81605	270	27	and	and	CCONJ
bjp-81605	270	28	impact	impact	NOUN
bjp-81605	270	29	on	on	ADP
bjp-81605	270	30	outcomes	outcome	NOUN
bjp-81605	270	31	.	.	PUNCT
bjp-81605	271	1	curr	curr	VERB
bjp-81605	271	2	drug	drug	NOUN
bjp-81605	271	3	targets	target	NOUN
bjp-81605	271	4	.	.	PUNCT
bjp-81605	272	1	2021	2021	NUM
bjp-81605	272	2	;	;	PUNCT
bjp-81605	272	3	22	22	NUM
bjp-81605	272	4	:	:	PUNCT
bjp-81605	272	5	998	998	NUM
bjp-81605	272	6	-	-	SYM
bjp-81605	272	7	1009	1009	NUM
bjp-81605	272	8	.	.	PUNCT
bjp-81605	273	1	behelgardi	behelgardi	PROPN
bjp-81605	273	2	m	m	PROPN
bjp-81605	273	3	,	,	PUNCT
bjp-81605	273	4	zahri	zahri	PROPN
bjp-81605	273	5	s	s	PROPN
bjp-81605	273	6	,	,	PUNCT
bjp-81605	273	7	mashayekhi	mashayekhi	PROPN
bjp-81605	273	8	f	f	PROPN
bjp-81605	273	9	,	,	PUNCT
bjp-81605	273	10	mansouri	mansouri	PROPN
bjp-81605	273	11	k	k	PROPN
bjp-81605	273	12	,	,	PUNCT
bjp-81605	273	13	asghari	asghari	PROPN
bjp-81605	273	14	sm	sm	INTJ
bjp-81605	273	15	.	.	PUNCT
bjp-81605	274	1	a	a	DET
bjp-81605	274	2	peptide	peptide	NOUN
bjp-81605	274	3	mimicking	mimic	VERB
bjp-81605	274	4	the	the	DET
bjp-81605	274	5	binding	bind	VERB
bjp-81605	274	6	sites	site	NOUN
bjp-81605	274	7	of	of	ADP
bjp-81605	274	8	vegf	vegf	PROPN
bjp-81605	274	9	-	-	PUNCT
bjp-81605	274	10	a	a	PROPN
bjp-81605	274	11	and	and	CCONJ
bjp-81605	274	12	vegf	vegf	PROPN
bjp-81605	274	13	-	-	PUNCT
bjp-81605	274	14	b	b	PROPN
bjp-81605	274	15	inhibits	inhibit	VERB
bjp-81605	274	16	vegfr-1/-2	vegfr-1/-2	NOUN
bjp-81605	274	17	driven	drive	VERB
bjp-81605	274	18	angiogenesis	angiogenesis	NOUN
bjp-81605	274	19	,	,	PUNCT
bjp-81605	274	20	tumor	tumor	NOUN
bjp-81605	274	21	growth	growth	NOUN
bjp-81605	274	22	and	and	CCONJ
bjp-81605	274	23	metastasis	metastasis	NOUN
bjp-81605	274	24	.	.	PUNCT
bjp-81605	275	1	sci	sci	PROPN
bjp-81605	275	2	rep	rep	PROPN
bjp-81605	275	3	.	.	PROPN
bjp-81605	275	4	2018	2018	NUM
bjp-81605	275	5	;	;	PUNCT
bjp-81605	275	6	8	8	NUM
bjp-81605	275	7	:	:	SYM
bjp-81605	275	8	17	17	NUM
bjp-81605	275	9	-	-	SYM
bjp-81605	275	10	24	24	NUM
bjp-81605	275	11	.	.	PUNCT
bjp-81605	276	1	cingeetham	cingeetham	PROPN
bjp-81605	276	2	a	a	PRON
bjp-81605	276	3	,	,	PUNCT
bjp-81605	276	4	vuree	vuree	NOUN
bjp-81605	276	5	s	s	NOUN
bjp-81605	276	6	,	,	PUNCT
bjp-81605	276	7	dunna	dunna	PROPN
bjp-81605	276	8	nr	nr	PROPN
bjp-81605	276	9	,	,	PUNCT
bjp-81605	276	10	gorre	gorre	PROPN
bjp-81605	276	11	m	m	PROPN
bjp-81605	276	12	,	,	PUNCT
bjp-81605	276	13	nanchari	nanchari	PROPN
bjp-81605	276	14	sr	sr	PROPN
bjp-81605	276	15	,	,	PUNCT
bjp-81605	276	16	edathara	edathara	PROPN
bjp-81605	276	17	pm	pm	PROPN
bjp-81605	276	18	.	.	PUNCT
bjp-81605	277	1	influence	influence	NOUN
bjp-81605	277	2	of	of	ADP
bjp-81605	277	3	bcl2	bcl2	PROPN
bjp-81605	277	4	-	-	PUNCT
bjp-81605	277	5	938	938	NUM
bjp-81605	277	6	and	and	CCONJ
bjp-81605	277	7	bax-248	bax-248	ADJ
bjp-81605	277	8	promoter	promoter	NOUN
bjp-81605	277	9	polymorphisms	polymorphism	NOUN
bjp-81605	277	10	in	in	ADP
bjp-81605	277	11	the	the	DET
bjp-81605	277	12	development	development	NOUN
bjp-81605	277	13	of	of	ADP
bjp-81605	277	14	aml	aml	PROPN
bjp-81605	277	15	:	:	PUNCT
bjp-81605	277	16	case	case	NOUN
bjp-81605	277	17	-	-	PUNCT
bjp-81605	277	18	control	control	NOUN
bjp-81605	277	19	study	study	NOUN
bjp-81605	277	20	from	from	ADP
bjp-81605	277	21	south	south	PROPN
bjp-81605	277	22	india	india	PROPN
bjp-81605	277	23	.	.	PUNCT
bjp-81605	278	1	tumor	tumor	PROPN
bjp-81605	278	2	biol	biol	PROPN
bjp-81605	278	3	.	.	PUNCT
bjp-81605	279	1	2015	2015	NUM
bjp-81605	279	2	;	;	PUNCT
bjp-81605	279	3	36	36	NUM
bjp-81605	279	4	:	:	SYM
bjp-81605	279	5	7967	7967	NUM
bjp-81605	279	6	-	-	SYM
bjp-81605	279	7	76	76	NUM
bjp-81605	279	8	.	.	PUNCT
bjp-81605	280	1	dey	dey	PROPN
bjp-81605	280	2	d	d	PROPN
bjp-81605	280	3	k	k	PROPN
bjp-81605	280	4	,	,	PUNCT
bjp-81605	280	5	kang	kang	PROPN
bjp-81605	280	6	s	s	PROPN
bjp-81605	280	7	c.	c.	PROPN
bjp-81605	280	8	copa3	copa3	PROPN
bjp-81605	280	9	peptide	peptide	PROPN
bjp-81605	280	10	induces	induce	VERB
bjp-81605	280	11	permanent	permanent	ADJ
bjp-81605	280	12	cellcycle	cellcycle	NOUN
bjp-81605	280	13	arrest	arrest	NOUN
bjp-81605	280	14	in	in	ADP
bjp-81605	280	15	colorectal	colorectal	ADJ
bjp-81605	280	16	cancer	cancer	NOUN
bjp-81605	280	17	cells	cell	NOUN
bjp-81605	280	18	.	.	PUNCT
bjp-81605	281	1	mechanisms	mechanism	NOUN
bjp-81605	281	2	of	of	ADP
bjp-81605	281	3	ageing	ageing	NOUN
bjp-81605	281	4	and	and	CCONJ
bjp-81605	281	5	development	development	NOUN
bjp-81605	281	6	.	.	PUNCT
bjp-81605	281	7	2021	2021	NUM
bjp-81605	281	8	;	;	PUNCT
bjp-81605	281	9	11	11	NUM
bjp-81605	281	10	:	:	SYM
bjp-81605	281	11	14	14	NUM
bjp-81605	281	12	-	-	SYM
bjp-81605	281	13	27	27	NUM
bjp-81605	281	14	.	.	PUNCT
bjp-81605	282	1	dia	dia	PROPN
bjp-81605	282	2	vp	vp	PROPN
bjp-81605	282	3	,	,	PUNCT
bjp-81605	282	4	krishnan	krishnan	PROPN
bjp-81605	282	5	hb	hb	PROPN
bjp-81605	282	6	.	.	PUNCT
bjp-81605	282	7	bg-4	bg-4	X
bjp-81605	282	8	a	a	DET
bjp-81605	282	9	novel	novel	ADJ
bjp-81605	282	10	anticancer	anticancer	NOUN
bjp-81605	282	11	peptide	peptide	NOUN
bjp-81605	282	12	from	from	ADP
bjp-81605	282	13	bitter	bitter	ADJ
bjp-81605	282	14	gourd	gourd	NOUN
bjp-81605	282	15	momordica	momordica	PROPN
bjp-81605	282	16	charantia	charantia	PROPN
bjp-81605	282	17	promotes	promote	VERB
bjp-81605	282	18	apoptosis	apoptosis	NOUN
bjp-81605	282	19	in	in	ADP
bjp-81605	282	20	human	human	ADJ
bjp-81605	282	21	colon	colon	NOUN
bjp-81605	282	22	cancer	cancer	NOUN
bjp-81605	282	23	cells	cell	NOUN
bjp-81605	282	24	.	.	PUNCT
bjp-81605	283	1	sci	sci	PROPN
bjp-81605	283	2	rep	rep	PROPN
bjp-81605	283	3	.	.	PROPN
bjp-81605	283	4	2016	2016	NUM
bjp-81605	283	5	;	;	PUNCT
bjp-81605	283	6	1	1	NUM
bjp-81605	283	7	:	:	SYM
bjp-81605	283	8	165	165	NUM
bjp-81605	283	9	-	-	SYM
bjp-81605	283	10	84	84	NUM
bjp-81605	283	11	.	.	PUNCT
bjp-81605	284	1	fantoukh	fantoukh	PROPN
bjp-81605	284	2	oi	oi	INTJ
bjp-81605	284	3	,	,	PUNCT
bjp-81605	284	4	al	al	PROPN
bjp-81605	284	5	-	-	PUNCT
bjp-81605	284	6	hamoud	hamoud	PROPN
bjp-81605	284	7	ga	ga	PROPN
bjp-81605	284	8	,	,	PUNCT
bjp-81605	284	9	nasr	nasr	PROPN
bjp-81605	284	10	fa	fa	PROPN
bjp-81605	284	11	,	,	PUNCT
bjp-81605	284	12	almarfadi	almarfadi	NOUN
bjp-81605	284	13	om	om	PROPN
bjp-81605	284	14	,	,	PUNCT
bjp-81605	284	15	hawwal	hawwal	NOUN
bjp-81605	284	16	mf	mf	PROPN
bjp-81605	284	17	,	,	PUNCT
bjp-81605	284	18	ali	ali	PROPN
bjp-81605	284	19	z.	z.	PROPN
bjp-81605	284	20	revisiting	revisit	VERB
bjp-81605	284	21	the	the	DET
bjp-81605	284	22	flora	flora	NOUN
bjp-81605	284	23	of	of	ADP
bjp-81605	284	24	saudi	saudi	PROPN
bjp-81605	284	25	arabia	arabia	PROPN
bjp-81605	284	26	phytochemical	phytochemical	ADJ
bjp-81605	284	27	and	and	CCONJ
bjp-81605	284	28	biological	biological	ADJ
bjp-81605	284	29	investigation	investigation	NOUN
bjp-81605	284	30	of	of	ADP
bjp-81605	284	31	the	the	DET
bjp-81605	284	32	endangered	endangered	ADJ
bjp-81605	284	33	plant	plant	NOUN
bjp-81605	284	34	species	specie	NOUN
bjp-81605	284	35	euphorbia	euphorbia	ADJ
bjp-81605	284	36	saudi	saudi	ADJ
bjp-81605	284	37	arabica	arabica	NOUN
bjp-81605	284	38	.	.	PUNCT
bjp-81605	285	1	j	j	NOUN
bjp-81605	285	2	metabolites	metabolite	NOUN
bjp-81605	285	3	.	.	PUNCT
bjp-81605	286	1	2023	2023	NUM
bjp-81605	286	2	;	;	PUNCT
bjp-81605	286	3	13	13	NUM
bjp-81605	286	4	:	:	SYM
bjp-81605	286	5	55	55	NUM
bjp-81605	286	6	-	-	SYM
bjp-81605	286	7	62	62	NUM
bjp-81605	286	8	.	.	PUNCT
bjp-81605	286	9	han	han	PROPN
bjp-81605	286	10	ky	ky	PROPN
bjp-81605	286	11	,	,	PUNCT
bjp-81605	286	12	chang	chang	PROPN
bjp-81605	286	13	jh	jh	PROPN
bjp-81605	286	14	,	,	PUNCT
bjp-81605	286	15	azar	azar	PROPN
bjp-81605	286	16	dt	dt	PROPN
bjp-81605	286	17	.	.	PUNCT
bjp-81605	287	1	mmp14	mmp14	PROPN
bjp-81605	287	2	containing	contain	VERB
bjp-81605	287	3	exosomes	exosome	NOUN
bjp-81605	287	4	cleave	cleave	VERB
bjp-81605	287	5	vegfr1	vegfr1	NOUN
bjp-81605	287	6	and	and	CCONJ
bjp-81605	287	7	promote	promote	VERB
bjp-81605	287	8	vegfa	vegfa	NOUN
bjp-81605	287	9	-	-	PUNCT
bjp-81605	287	10	induced	induce	VERB
bjp-81605	287	11	migration	migration	NOUN
bjp-81605	287	12	and	and	CCONJ
bjp-81605	287	13	proliferation	proliferation	NOUN
bjp-81605	287	14	of	of	ADP
bjp-81605	287	15	vascular	vascular	ADJ
bjp-81605	287	16	endothelial	endothelial	ADJ
bjp-81605	287	17	cells	cell	NOUN
bjp-81605	287	18	.	.	PUNCT
bjp-81605	288	1	invest	invest	VERB
bjp-81605	288	2	ophthalmol	ophthalmol	PROPN
bjp-81605	288	3	visual	visual	PROPN
bjp-81605	288	4	sci	sci	PROPN
bjp-81605	288	5	.	.	PROPN
bjp-81605	288	6	2019	2019	NUM
bjp-81605	288	7	;	;	PUNCT
bjp-81605	288	8	60	60	NUM
bjp-81605	288	9	:	:	SYM
bjp-81605	288	10	23	23	NUM
bjp-81605	288	11	-	-	SYM
bjp-81605	288	12	31	31	NUM
bjp-81605	288	13	.	.	PUNCT
bjp-81605	289	1	he	he	PRON
bjp-81605	289	2	l	l	PROPN
bjp-81605	289	3	,	,	PUNCT
bjp-81605	289	4	lu	lu	PROPN
bjp-81605	289	5	n	n	CCONJ
bjp-81605	289	6	,	,	PUNCT
bjp-81605	289	7	dai	dai	PROPN
bjp-81605	289	8	q	q	PROPN
bjp-81605	289	9	,	,	PUNCT
bjp-81605	289	10	zhao	zhao	PROPN
bjp-81605	289	11	y	y	PROPN
bjp-81605	289	12	,	,	PUNCT
bjp-81605	289	13	zhao	zhao	PROPN
bjp-81605	289	14	l	l	PROPN
bjp-81605	289	15	,	,	PUNCT
bjp-81605	289	16	wang	wang	PROPN
bjp-81605	289	17	,	,	PUNCT
bjp-81605	289	18	h	h	PROPN
bjp-81605	289	19	li	li	PROPN
bjp-81605	290	1	z	z	PROPN
bjp-81605	290	2	,	,	PUNCT
bjp-81605	290	3	you	you	PRON
bjp-81605	290	4	q	q	ADJ
bjp-81605	290	5	,	,	PUNCT
bjp-81605	290	6	guo	guo	PROPN
bjp-81605	290	7	q.	q.	PROPN
bjp-81605	290	8	wogonin	wogonin	PROPN
bjp-81605	290	9	induced	induce	VERB
bjp-81605	290	10	g1	g1	PROPN
bjp-81605	290	11	cell	cell	NOUN
bjp-81605	290	12	cycle	cycle	NOUN
bjp-81605	290	13	arrest	arrest	NOUN
bjp-81605	290	14	by	by	ADP
bjp-81605	290	15	regulating	regulate	VERB
bjp-81605	290	16	wnt/	wnt/	NOUN
bjp-81605	290	17	β	β	NOUN
bjp-81605	290	18	-	-	ADJ
bjp-81605	290	19	catenin	catenin	ADJ
bjp-81605	290	20	signaling	signal	VERB
bjp-81605	290	21	pathway	pathway	NOUN
bjp-81605	290	22	and	and	CCONJ
bjp-81605	290	23	inactivating	inactivate	VERB
bjp-81605	290	24	cdk8	cdk8	NOUN
bjp-81605	290	25	in	in	ADP
bjp-81605	290	26	human	human	ADJ
bjp-81605	290	27	colorectal	colorectal	ADJ
bjp-81605	290	28	cancer	cancer	NOUN
bjp-81605	290	29	carcinoma	carcinoma	NOUN
bjp-81605	290	30	cells	cell	NOUN
bjp-81605	290	31	.	.	PUNCT
bjp-81605	291	1	toxicology	toxicology	NOUN
bjp-81605	291	2	2013	2013	NUM
bjp-81605	291	3	;	;	PUNCT
bjp-81605	291	4	31	31	NUM
bjp-81605	291	5	:	:	SYM
bjp-81605	291	6	36	36	NUM
bjp-81605	291	7	-	-	SYM
bjp-81605	291	8	47	47	NUM
bjp-81605	291	9	.	.	PUNCT
bjp-81605	292	1	jin	jin	PROPN
bjp-81605	292	2	c	c	PROPN
bjp-81605	292	3	,	,	PUNCT
bjp-81605	292	4	chen	chen	PROPN
bjp-81605	292	5	j	j	PROPN
bjp-81605	292	6	,	,	PUNCT
bjp-81605	292	7	cheng	cheng	PROPN
bjp-81605	292	8	y	y	PROPN
bjp-81605	292	9	,	,	PUNCT
bjp-81605	292	10	fu	fu	PROPN
bjp-81605	292	11	y	y	PROPN
bjp-81605	292	12	,	,	PUNCT
bjp-81605	292	13	zhao	zhao	PROPN
bjp-81605	292	14	h	h	PROPN
bjp-81605	292	15	,	,	PUNCT
bjp-81605	292	16	tang	tang	PROPN
bjp-81605	292	17	m.	m.	NOUN
bjp-81605	292	18	mesenchymal	mesenchymal	NOUN
bjp-81605	292	19	stem	stem	NOUN
bjp-81605	292	20	cell	cell	NOUN
bjp-81605	292	21	-	-	PUNCT
bjp-81605	292	22	derived	derive	VERB
bjp-81605	292	23	exosomes	exosome	NOUN
bjp-81605	292	24	protect	protect	VERB
bjp-81605	292	25	beta	beta	ADJ
bjp-81605	292	26	cells	cell	NOUN
bjp-81605	292	27	against	against	ADP
bjp-81605	292	28	hypoxia	hypoxia	NOUN
bjp-81605	292	29	-	-	PUNCT
bjp-81605	292	30	induced	induce	VERB
bjp-81605	292	31	apoptosis	apoptosis	NOUN
bjp-81605	292	32	via	via	ADP
bjp-81605	292	33	mir-21	mir-21	PROPN
bjp-81605	292	34	by	by	ADP
bjp-81605	292	35	alleviating	alleviate	VERB
bjp-81605	292	36	er	er	INTJ
bjp-81605	292	37	stress	stress	NOUN
bjp-81605	292	38	and	and	CCONJ
bjp-81605	292	39	inhibiting	inhibit	VERB
bjp-81605	292	40	p38	p38	NOUN
bjp-81605	292	41	mapk	mapk	NOUN
bjp-81605	292	42	phosphorylation	phosphorylation	NOUN
bjp-81605	292	43	.	.	PUNCT
bjp-81605	293	1	curr	curr	PROPN
bjp-81605	293	2	cancer	cancer	PROPN
bjp-81605	293	3	drug	drug	PROPN
bjp-81605	293	4	targ	targ	PROPN
bjp-81605	293	5	.	.	PUNCT
bjp-81605	294	1	2020	2020	NUM
bjp-81605	294	2	;	;	PUNCT
bjp-81605	294	3	11	11	NUM
bjp-81605	294	4	:	:	SYM
bjp-81605	294	5	65	65	NUM
bjp-81605	294	6	-	-	SYM
bjp-81605	294	7	79	79	NUM
bjp-81605	294	8	.	.	PUNCT
bjp-81605	295	1	mabeta	mabeta	PROPN
bjp-81605	295	2	p	p	NOUN
bjp-81605	295	3	,	,	PUNCT
bjp-81605	295	4	steenkamp	steenkamp	PROPN
bjp-81605	295	5	v.	v.	ADP
bjp-81605	295	6	the	the	DET
bjp-81605	295	7	vegf	vegf	PROPN
bjp-81605	295	8	/	/	SYM
bjp-81605	295	9	vegfr	vegfr	PROPN
bjp-81605	295	10	axis	axis	NOUN
bjp-81605	295	11	revisited	revisit	VERB
bjp-81605	295	12	implications	implication	NOUN
bjp-81605	295	13	for	for	ADP
bjp-81605	295	14	cancer	cancer	NOUN
bjp-81605	295	15	therapy	therapy	NOUN
bjp-81605	295	16	.	.	PUNCT
bjp-81605	296	1	int	int	PROPN
bjp-81605	296	2	j	j	PROPN
bjp-81605	296	3	mol	mol	ADP
bjp-81605	296	4	sci	sci	PROPN
bjp-81605	296	5	.	.	PROPN
bjp-81605	296	6	2022	2022	NUM
bjp-81605	296	7	;	;	PUNCT
bjp-81605	296	8	24	24	NUM
bjp-81605	296	9	:	:	SYM
bjp-81605	296	10	15585	15585	NUM
bjp-81605	296	11	.	.	PUNCT
bjp-81605	297	1	mc	mc	PROPN
bjp-81605	297	2	cubrey	cubrey	PROPN
bjp-81605	297	3	ja	ja	PROPN
bjp-81605	297	4	,	,	PUNCT
bjp-81605	297	5	steelman	steelman	PROPN
bjp-81605	297	6	ls	ls	PROPN
bjp-81605	297	7	,	,	PUNCT
bjp-81605	297	8	abrams	abrams	PROPN
bjp-81605	297	9	sl	sl	PROPN
bjp-81605	297	10	,	,	PUNCT
bjp-81605	297	11	lee	lee	PROPN
bjp-81605	297	12	jt	jt	PROPN
bjp-81605	297	13	,	,	PUNCT
bjp-81605	297	14	chang	chang	PROPN
bjp-81605	297	15	f	f	PROPN
bjp-81605	297	16	,	,	PUNCT
bjp-81605	297	17	bertrand	bertrand	PROPN
bjp-81605	297	18	fe	fe	PROPN
bjp-81605	297	19	.	.	PROPN
bjp-81605	297	20	roles	role	NOUN
bjp-81605	297	21	of	of	ADP
bjp-81605	297	22	the	the	DET
bjp-81605	297	23	raf	raf	PROPN
bjp-81605	297	24	/	/	SYM
bjp-81605	297	25	mek	mek	PROPN
bjp-81605	297	26	/	/	SYM
bjp-81605	297	27	erk	erk	PROPN
bjp-81605	297	28	and	and	CCONJ
bjp-81605	297	29	pi3k/	pi3k/	PROPN
bjp-81605	297	30	pten	pten	NOUN
bjp-81605	297	31	/	/	SYM
bjp-81605	297	32	akt	akt	PROPN
bjp-81605	297	33	pathways	pathway	NOUN
bjp-81605	297	34	in	in	ADP
bjp-81605	297	35	malignant	malignant	ADJ
bjp-81605	297	36	transformation	transformation	NOUN
bjp-81605	297	37	and	and	CCONJ
bjp-81605	297	38	drug	drug	NOUN
bjp-81605	297	39	resistance	resistance	NOUN
bjp-81605	297	40	.	.	PUNCT
bjp-81605	298	1	adv	adv	PROPN
bjp-81605	298	2	enzyme	enzyme	VERB
bjp-81605	298	3	reg	reg	NOUN
bjp-81605	298	4	.	.	PUNCT
bjp-81605	299	1	2006	2006	NUM
bjp-81605	299	2	;	;	PUNCT
bjp-81605	299	3	46	46	NUM
bjp-81605	299	4	:	:	PUNCT
bjp-81605	299	5	249	249	NUM
bjp-81605	299	6	-	-	SYM
bjp-81605	299	7	79	79	NUM
bjp-81605	299	8	.	.	PUNCT
bjp-81605	300	1	mccauley	mccauley	PROPN
bjp-81605	300	2	j	j	PROPN
bjp-81605	300	3	,	,	PUNCT
bjp-81605	300	4	zivanovic	zivanovic	PROPN
bjp-81605	300	5	a	a	X
bjp-81605	300	6	,	,	PUNCT
bjp-81605	300	7	skropeta	skropeta	PROPN
bjp-81605	300	8	d.	d.	PROPN
bjp-81605	300	9	bioassays	bioassay	VERB
bjp-81605	300	10	for	for	ADP
bjp-81605	300	11	anticancer	anticancer	NOUN
bjp-81605	300	12	activities	activity	NOUN
bjp-81605	300	13	.	.	PUNCT
bjp-81605	301	1	methods	method	NOUN
bjp-81605	301	2	mol	mol	ADP
bjp-81605	301	3	biol	biol	PROPN
bjp-81605	301	4	.	.	PUNCT
bjp-81605	302	1	2013	2013	NUM
bjp-81605	302	2	;	;	PUNCT
bjp-81605	302	3	55	55	NUM
bjp-81605	302	4	:	:	SYM
bjp-81605	302	5	191	191	NUM
bjp-81605	302	6	-	-	SYM
bjp-81605	302	7	205	205	NUM
bjp-81605	302	8	.	.	PUNCT
bjp-81605	303	1	pravdic	pravdic	PROPN
bjp-81605	303	2	z	z	PROPN
bjp-81605	303	3	,	,	PUNCT
bjp-81605	303	4	vukovic	vukovic	ADJ
bjp-81605	303	5	ns	ns	ADJ
bjp-81605	303	6	,	,	PUNCT
bjp-81605	303	7	gasic	gasic	NOUN
bjp-81605	303	8	v	v	NOUN
bjp-81605	303	9	,	,	PUNCT
bjp-81605	303	10	marjanovic	marjanovic	PROPN
bjp-81605	303	11	i	i	PROPN
bjp-81605	303	12	,	,	PUNCT
bjp-81605	303	13	karandjurasevic	karandjurasevic	PROPN
bjp-81605	303	14	t	t	PROPN
bjp-81605	303	15	,	,	PUNCT
bjp-81605	303	16	pavlovic	pavlovic	PROPN
bjp-81605	303	17	s.	s.	PROPN
bjp-81605	303	18	the	the	DET
bjp-81605	303	19	influence	influence	NOUN
bjp-81605	303	20	of	of	ADP
bjp-81605	303	21	bcl2	bcl2	PROPN
bjp-81605	303	22	bax	bax	PROPN
bjp-81605	303	23	and	and	CCONJ
bjp-81605	303	24	abcb1	abcb1	NOUN
bjp-81605	303	25	gene	gene	NOUN
bjp-81605	303	26	expression	expression	NOUN
bjp-81605	303	27	on	on	ADP
bjp-81605	303	28	prognosis	prognosis	NOUN
bjp-81605	303	29	of	of	ADP
bjp-81605	303	30	adult	adult	NOUN
bjp-81605	303	31	de	de	X
bjp-81605	303	32	novo	novo	PROPN
bjp-81605	303	33	acute	acute	PROPN
bjp-81605	303	34	myeloid	myeloid	PROPN
bjp-81605	303	35	leukemia	leukemia	NOUN
bjp-81605	303	36	with	with	ADP
bjp-81605	303	37	normal	normal	ADJ
bjp-81605	303	38	karyotype	karyotype	NOUN
bjp-81605	303	39	patients	patient	NOUN
bjp-81605	303	40	.	.	PUNCT
bjp-81605	304	1	radiol	radiol	PROPN
bjp-81605	304	2	oncol	oncol	ADJ
bjp-81605	304	3	.	.	PUNCT
bjp-81605	305	1	2023	2023	NUM
bjp-81605	305	2	;	;	PUNCT
bjp-81605	305	3	57	57	NUM
bjp-81605	305	4	:	:	SYM
bjp-81605	305	5	239	239	NUM
bjp-81605	305	6	-	-	SYM
bjp-81605	305	7	48	48	NUM
bjp-81605	305	8	.	.	PUNCT
bjp-81605	306	1	rasaratnam	rasaratnam	NOUN
bjp-81605	306	2	k	k	NOUN
bjp-81605	306	3	,	,	PUNCT
bjp-81605	306	4	nantasenamat	nantasenamat	ADJ
bjp-81605	306	5	c	c	NOUN
bjp-81605	306	6	,	,	PUNCT
bjp-81605	306	7	phaonakrop	phaonakrop	NOUN
bjp-81605	306	8	n	n	CCONJ
bjp-81605	306	9	,	,	PUNCT
bjp-81605	306	10	roytrakul	roytrakul	VERB
bjp-81605	306	11	s	s	PROPN
bjp-81605	306	12	,	,	PUNCT
bjp-81605	306	13	tanyong	tanyong	PROPN
bjp-81605	306	14	d.	d.	PROPN
bjp-81605	306	15	a	a	DET
bjp-81605	306	16	novel	novel	NOUN
bjp-81605	306	17	peptide	peptide	NOUN
bjp-81605	306	18	isolated	isolate	VERB
bjp-81605	306	19	from	from	ADP
bjp-81605	306	20	garlic	garlic	PROPN
bjp-81605	306	21	shows	show	NOUN
bjp-81605	306	22	anticancer	anticancer	NOUN
bjp-81605	306	23	effect	effect	NOUN
bjp-81605	306	24	against	against	ADP
bjp-81605	306	25	leukemic	leukemic	ADJ
bjp-81605	306	26	cell	cell	NOUN
bjp-81605	306	27	lines	line	NOUN
bjp-81605	306	28	via	via	ADP
bjp-81605	306	29	interaction	interaction	NOUN
bjp-81605	306	30	with	with	ADP
bjp-81605	306	31	bcl‐2	bcl‐2	NOUN
bjp-81605	306	32	family	family	NOUN
bjp-81605	306	33	proteins	protein	NOUN
bjp-81605	306	34	.	.	PUNCT
bjp-81605	307	1	chem	chem	NOUN
bjp-81605	307	2	biol	biol	PROPN
bjp-81605	307	3	drug	drug	PROPN
bjp-81605	307	4	des	des	PROPN
bjp-81605	307	5	.	.	PROPN
bjp-81605	307	6	2021	2021	NUM
bjp-81605	307	7	;	;	PUNCT
bjp-81605	307	8	97	97	NUM
bjp-81605	307	9	:	:	SYM
bjp-81605	307	10	17	17	NUM
bjp-81605	307	11	-28	-28	NUM
bjp-81605	307	12	.	.	PUNCT
bjp-81605	308	1	santhosha	santhosha	PROPN
bjp-81605	308	2	sg	sg	PROPN
bjp-81605	308	3	,	,	PUNCT
bjp-81605	308	4	jamuna	jamuna	PROPN
bjp-81605	308	5	p	p	X
bjp-81605	308	6	,	,	PUNCT
bjp-81605	308	7	prabhavathi	prabhavathi	PROPN
bjp-81605	308	8	sn	sn	PROPN
bjp-81605	308	9	.	.	PUNCT
bjp-81605	309	1	bioactive	bioactive	PROPN
bjp-81605	309	2	compo	compo	PROPN
bjp-81605	309	3	bangladesh	bangladesh	PROPN
bjp-81605	309	4	j	j	PROPN
bjp-81605	309	5	pharmacol	pharmacol	PROPN
bjp-81605	309	6	2025	2025	NUM
bjp-81605	309	7	;	;	PUNCT
bjp-81605	309	8	20	20	NUM
bjp-81605	309	9	:	:	SYM
bjp-81605	309	10	89	89	NUM
bjp-81605	309	11	-	-	SYM
bjp-81605	309	12	100	100	NUM
bjp-81605	309	13	99	99	NUM
bjp-81605	309	14	author	author	NOUN
bjp-81605	309	15	info	info	NOUN
bjp-81605	309	16	ramanathan	ramanathan	PROPN
bjp-81605	309	17	muthiah	muthiah	PROPN
bjp-81605	309	18	(	(	PUNCT
bjp-81605	309	19	principal	principal	ADJ
bjp-81605	309	20	contact	contact	NOUN
bjp-81605	309	21	)	)	PUNCT
bjp-81605	310	1	e	e	NOUN
bjp-81605	310	2	-	-	NOUN
bjp-81605	310	3	mail	mail	NOUN
bjp-81605	310	4	:	:	PUNCT
bjp-81605	310	5	ramanathanm@psgpharma.ac.in	ramanathanm@psgpharma.ac.in	ADJ
bjp-81605	310	6	nents	nent	NOUN
bjp-81605	310	7	of	of	ADP
bjp-81605	310	8	garlic	garlic	NOUN
bjp-81605	310	9	and	and	CCONJ
bjp-81605	310	10	their	their	PRON
bjp-81605	310	11	physiological	physiological	ADJ
bjp-81605	310	12	role	role	NOUN
bjp-81605	310	13	in	in	ADP
bjp-81605	310	14	health	health	NOUN
bjp-81605	310	15	maintenance	maintenance	NOUN
bjp-81605	310	16	.	.	PUNCT
bjp-81605	311	1	food	food	NOUN
bjp-81605	311	2	biosci	biosci	PROPN
bjp-81605	311	3	.	.	PUNCT
bjp-81605	312	1	2013	2013	NUM
bjp-81605	312	2	;	;	PUNCT
bjp-81605	312	3	3	3	NUM
bjp-81605	312	4	:	:	SYM
bjp-81605	312	5	59	59	NUM
bjp-81605	312	6	-	-	SYM
bjp-81605	312	7	74	74	NUM
bjp-81605	312	8	.	.	PUNCT
bjp-81605	313	1	shobeiri	shobeiri	PROPN
bjp-81605	313	2	ss	ss	PROPN
bjp-81605	313	3	,	,	PUNCT
bjp-81605	313	4	sankian	sankian	ADJ
bjp-81605	313	5	m.	m.	NOUN
bjp-81605	313	6	polyvinyl	polyvinyl	NOUN
bjp-81605	313	7	alcohol	alcohol	NOUN
bjp-81605	313	8	can	can	AUX
bjp-81605	313	9	stabilize	stabilize	VERB
bjp-81605	313	10	fitc	fitc	NOUN
bjp-81605	313	11	conjugated	conjugate	VERB
bjp-81605	313	12	recombinant	recombinant	ADJ
bjp-81605	313	13	annexin	annexin	NOUN
bjp-81605	313	14	v	v	NOUN
bjp-81605	313	15	for	for	ADP
bjp-81605	313	16	apoptotic	apoptotic	ADJ
bjp-81605	313	17	cells	cell	NOUN
bjp-81605	313	18	detection	detection	NOUN
bjp-81605	313	19	.	.	PUNCT
bjp-81605	314	1	protein	protein	NOUN
bjp-81605	314	2	pep	pep	INTJ
bjp-81605	314	3	lett	lett	PROPN
bjp-81605	314	4	.	.	PROPN
bjp-81605	314	5	2022	2022	NUM
bjp-81605	314	6	;	;	PUNCT
bjp-81605	314	7	29	29	NUM
bjp-81605	314	8	:	:	PUNCT
bjp-81605	314	9	806	806	NUM
bjp-81605	314	10	-	-	SYM
bjp-81605	314	11	14	14	NUM
bjp-81605	314	12	.	.	PUNCT
bjp-81605	315	1	tokunaga	tokunaga	PROPN
bjp-81605	315	2	e	e	NOUN
bjp-81605	315	3	,	,	PUNCT
bjp-81605	315	4	oki	oki	NOUN
bjp-81605	315	5	e	e	NOUN
bjp-81605	315	6	,	,	PUNCT
bjp-81605	315	7	egashira	egashira	PROPN
bjp-81605	315	8	a	a	PRON
bjp-81605	315	9	,	,	PUNCT
bjp-81605	315	10	sadanaga	sadanaga	NOUN
bjp-81605	315	11	n	n	CCONJ
bjp-81605	315	12	,	,	PUNCT
bjp-81605	315	13	morita	morita	PROPN
bjp-81605	315	14	m	m	PROPN
bjp-81605	315	15	,	,	PUNCT
bjp-81605	315	16	kakeji	kakeji	VERB
bjp-81605	315	17	y.	y.	PROPN
bjp-81605	315	18	deregulation	deregulation	NOUN
bjp-81605	315	19	of	of	ADP
bjp-81605	315	20	the	the	DET
bjp-81605	315	21	akt	akt	PROPN
bjp-81605	315	22	pathway	pathway	NOUN
bjp-81605	315	23	in	in	ADP
bjp-81605	315	24	human	human	ADJ
bjp-81605	315	25	cancer	cancer	NOUN
bjp-81605	315	26	.	.	PUNCT
bjp-81605	316	1	curr	curr	PROPN
bjp-81605	316	2	cancer	cancer	PROPN
bjp-81605	316	3	drug	drug	PROPN
bjp-81605	316	4	targ	targ	PROPN
bjp-81605	316	5	.	.	PUNCT
bjp-81605	316	6	2008	2008	NUM
bjp-81605	316	7	;	;	PUNCT
bjp-81605	316	8	8	8	NUM
bjp-81605	316	9	:	:	SYM
bjp-81605	316	10	27	27	NUM
bjp-81605	316	11	-	-	SYM
bjp-81605	316	12	36	36	NUM
bjp-81605	316	13	.	.	PUNCT
bjp-81605	317	1	wageesha	wageesha	PROPN
bjp-81605	317	2	nd	nd	PRON
bjp-81605	317	3	,	,	PUNCT
bjp-81605	317	4	soysa	soysa	NOUN
bjp-81605	317	5	p	p	NOUN
bjp-81605	317	6	,	,	PUNCT
bjp-81605	317	7	atthanayake	atthanayake	VERB
bjp-81605	317	8	k	k	PROPN
bjp-81605	317	9	,	,	PUNCT
bjp-81605	317	10	choudhary	choudhary	PROPN
bjp-81605	317	11	mi	mi	PROPN
bjp-81605	317	12	,	,	PUNCT
bjp-81605	317	13	ekanayake	ekanayake	NOUN
bjp-81605	317	14	m.	m.	NOUN
bjp-81605	317	15	a	a	DET
bjp-81605	317	16	traditional	traditional	ADJ
bjp-81605	317	17	poly	poly	ADJ
bjp-81605	317	18	herbal	herbal	ADJ
bjp-81605	317	19	medicine	medicine	NOUN
bjp-81605	317	20	“	"	PUNCT
bjp-81605	317	21	le	le	PROPN
bjp-81605	317	22	pana	pana	PROPN
bjp-81605	317	23	guliya	guliya	PROPN
bjp-81605	317	24	”	"	PUNCT
bjp-81605	317	25	induces	induce	VERB
bjp-81605	317	26	apoptosis	apoptosis	NOUN
bjp-81605	317	27	in	in	ADP
bjp-81605	317	28	hepg	hepg	NOUN
bjp-81605	317	29	2	2	NUM
bjp-81605	317	30	and	and	CCONJ
bjp-81605	317	31	hela	hela	ADJ
bjp-81605	317	32	cells	cell	NOUN
bjp-81605	317	33	but	but	CCONJ
bjp-81605	317	34	not	not	PART
bjp-81605	317	35	in	in	ADP
bjp-81605	317	36	cc1	cc1	NOUN
bjp-81605	317	37	cells	cell	NOUN
bjp-81605	317	38	:	:	PUNCT
bjp-81605	317	39	an	an	DET
bjp-81605	317	40	in	in	ADP
bjp-81605	317	41	vitro	vitro	X
bjp-81605	317	42	assessment	assessment	NOUN
bjp-81605	317	43	.	.	PUNCT
bjp-81605	318	1	chem	chem	PROPN
bjp-81605	318	2	central	central	PROPN
bjp-81605	318	3	j.	j.	PROPN
bjp-81605	318	4	2017	2017	NUM
bjp-81605	318	5	;	;	PUNCT
bjp-81605	318	6	2017	2017	NUM
bjp-81605	318	7	.	.	PUNCT
bjp-81605	319	1	wang	wang	PROPN
bjp-81605	319	2	r	r	PROPN
bjp-81605	319	3	,	,	PUNCT
bjp-81605	319	4	ma	ma	PROPN
bjp-81605	319	5	y	y	PROPN
bjp-81605	319	6	,	,	PUNCT
bjp-81605	319	7	zhan	zhan	PROPN
bjp-81605	319	8	s	s	PROPN
bjp-81605	319	9	,	,	PUNCT
bjp-81605	319	10	zhang	zhang	PROPN
bjp-81605	319	11	g	g	PROPN
bjp-81605	319	12	,	,	PUNCT
bjp-81605	319	13	cao	cao	PROPN
bjp-81605	319	14	l	l	PROPN
bjp-81605	319	15	,	,	PUNCT
bjp-81605	319	16	zhang	zhang	PROPN
bjp-81605	319	17	x	x	PROPN
bjp-81605	319	18	,	,	PUNCT
bjp-81605	319	19	shi	shi	PROPN
bjp-81605	319	20	t	t	PROPN
bjp-81605	319	21	,	,	PUNCT
bjp-81605	319	22	chen	chen	PROPN
bjp-81605	319	23	w.	w.	PROPN
bjp-81605	319	24	b7	b7	PROPN
bjp-81605	319	25	-	-	PUNCT
bjp-81605	319	26	h3	h3	NOUN
bjp-81605	319	27	promotes	promote	VERB
bjp-81605	319	28	colorectal	colorectal	ADJ
bjp-81605	319	29	cancer	cancer	NOUN
bjp-81605	319	30	angiogenesis	angiogenesis	NOUN
bjp-81605	319	31	through	through	ADP
bjp-81605	319	32	activating	activate	VERB
bjp-81605	319	33	the	the	DET
bjp-81605	319	34	nf	nf	ADJ
bjp-81605	319	35	-	-	PUNCT
bjp-81605	319	36	κb	κb	NOUN
bjp-81605	319	37	pathway	pathway	NOUN
bjp-81605	319	38	to	to	PART
bjp-81605	319	39	induce	induce	VERB
bjp-81605	319	40	vegfa	vegfa	ADP
bjp-81605	319	41	expression	expression	NOUN
bjp-81605	319	42	.	.	PUNCT
bjp-81605	320	1	cell	cell	NOUN
bjp-81605	320	2	death	death	NOUN
bjp-81605	320	3	dis	dis	PROPN
bjp-81605	320	4	.	.	PUNCT
bjp-81605	321	1	2020	2020	NUM
bjp-81605	321	2	;	;	PUNCT
bjp-81605	321	3	11	11	NUM
bjp-81605	321	4	:	:	SYM
bjp-81605	321	5	55	55	NUM
bjp-81605	321	6	-	-	SYM
bjp-81605	321	7	68	68	NUM
bjp-81605	321	8	.	.	PUNCT
bjp-81605	322	1	weitz	weitz	PROPN
bjp-81605	322	2	j	j	PROPN
bjp-81605	322	3	,	,	PUNCT
bjp-81605	322	4	koch	koch	PROPN
bjp-81605	322	5	m	m	PROPN
bjp-81605	322	6	,	,	PUNCT
bjp-81605	322	7	debus	debus	PROPN
bjp-81605	322	8	j	j	PROPN
bjp-81605	322	9	,	,	PUNCT
bjp-81605	322	10	hohler	hohler	PROPN
bjp-81605	322	11	t	t	PROPN
bjp-81605	322	12	,	,	PUNCT
bjp-81605	322	13	galle	galle	PROPN
bjp-81605	322	14	pr	pr	PROPN
bjp-81605	322	15	,	,	PUNCT
bjp-81605	322	16	buchler	buchler	PROPN
bjp-81605	322	17	mw	mw	PROPN
bjp-81605	322	18	.	.	PROPN
bjp-81605	322	19	colorectal	colorectal	ADJ
bjp-81605	322	20	cancer	cancer	NOUN
bjp-81605	322	21	.	.	PUNCT
bjp-81605	323	1	lancet	lancet	PROPN
bjp-81605	323	2	2005	2005	NUM
bjp-81605	323	3	;	;	PUNCT
bjp-81605	323	4	90	90	NUM
bjp-81605	323	5	:	:	SYM
bjp-81605	323	6	153	153	NUM
bjp-81605	323	7	-	-	SYM
bjp-81605	323	8	65	65	NUM
bjp-81605	323	9	.	.	PUNCT
bjp-81605	324	1	yogananthan	yogananthan	PROPN
bjp-81605	324	2	d	d	PROPN
bjp-81605	324	3	,	,	PUNCT
bjp-81605	324	4	raj	raj	PROPN
bjp-81605	324	5	a.	a.	PROPN
bjp-81605	324	6	,	,	PUNCT
bjp-81605	324	7	venkatachalam	venkatachalam	VERB
bjp-81605	324	8	k	k	PROPN
bjp-81605	324	9	,	,	PUNCT
bjp-81605	324	10	muthaiah	muthaiah	PROPN
bjp-81605	324	11	r.	r.	PROPN
bjp-81605	324	12	a	a	DET
bjp-81605	324	13	selectivity	selectivity	NOUN
bjp-81605	324	14	of	of	ADP
bjp-81605	324	15	super	super	ADJ
bjp-81605	324	16	-	-	ADJ
bjp-81605	324	17	short	short	ADJ
bjp-81605	324	18	peptide	peptide	NOUN
bjp-81605	324	19	morphed	morph	VERB
bjp-81605	324	20	hydrophilic	hydrophilic	ADJ
bjp-81605	324	21	and	and	CCONJ
bjp-81605	324	22	hydrophobic	hydrophobic	NOUN
bjp-81605	324	23	domains	domain	NOUN
bjp-81605	324	24	to	to	PART
bjp-81605	324	25	improve	improve	VERB
bjp-81605	324	26	anti	anti	ADJ
bjp-81605	324	27	-	-	ADJ
bjp-81605	324	28	cancer	cancer	ADJ
bjp-81605	324	29	efficacy	efficacy	NOUN
bjp-81605	324	30	.	.	PUNCT
bjp-81605	325	1	eur	eur	PROPN
bjp-81605	325	2	chem	chem	PROPN
bjp-81605	325	3	b.	b.	PROPN
bjp-81605	325	4	2023	2023	NUM
bjp-81605	325	5	;	;	PUNCT
bjp-81605	325	6	12	12	NUM
bjp-81605	325	7	:	:	SYM
bjp-81605	325	8	5381	5381	NUM
bjp-81605	325	9	-	-	SYM
bjp-81605	325	10	88	88	NUM
bjp-81605	325	11	.	.	PUNCT
bjp-81605	325	12	zanjanchi	zanjanchi	PROPN
bjp-81605	325	13	p	p	PROPN
bjp-81605	325	14	,	,	PUNCT
bjp-81605	325	15	asghari	asghari	PROPN
bjp-81605	325	16	sm	sm	PROPN
bjp-81605	325	17	,	,	PUNCT
bjp-81605	325	18	mohabatkar	mohabatkar	PROPN
bjp-81605	325	19	h	h	PROPN
bjp-81605	325	20	,	,	PUNCT
bjp-81605	325	21	shourian	shourian	PROPN
bjp-81605	325	22	m	m	PROPN
bjp-81605	325	23	,	,	PUNCT
bjp-81605	325	24	shafiee	shafiee	PROPN
bjp-81605	325	25	ardestani	ardestani	PROPN
bjp-81605	325	26	m.	m.	PROPN
bjp-81605	325	27	conjugation	conjugation	NOUN
bjp-81605	325	28	of	of	ADP
bjp-81605	325	29	vegfr1	vegfr1	PROPN
bjp-81605	325	30	/	/	SYM
bjp-81605	325	31	r2	r2	NOUN
bjp-81605	325	32	-	-	PUNCT
bjp-81605	325	33	targeting	target	VERB
bjp-81605	325	34	peptide	peptide	NOUN
bjp-81605	325	35	with	with	ADP
bjp-81605	325	36	gold	gold	ADJ
bjp-81605	325	37	nanoparticles	nanoparticle	NOUN
bjp-81605	325	38	to	to	PART
bjp-81605	325	39	enhance	enhance	VERB
bjp-81605	325	40	antiangiogenic	antiangiogenic	ADJ
bjp-81605	325	41	and	and	CCONJ
bjp-81605	325	42	antitumoral	antitumoral	ADJ
bjp-81605	325	43	activity	activity	NOUN
bjp-81605	325	44	.	.	PUNCT
bjp-81605	326	1	j	j	PROPN
bjp-81605	326	2	nanobiotechnol	nanobiotechnol	PROPN
bjp-81605	326	3	.	.	PUNCT
bjp-81605	327	1	2022	2022	NUM
bjp-81605	327	2	;	;	PUNCT
bjp-81605	327	3	20	20	NUM
bjp-81605	327	4	:	:	SYM
bjp-81605	327	5	7	7	NUM
bjp-81605	327	6	-	-	SYM
bjp-81605	327	7	21	21	NUM
bjp-81605	327	8	.	.	PUNCT
bjp-81605	328	1	zhang	zhang	PROPN
bjp-81605	328	2	d	d	PROPN
bjp-81605	328	3	,	,	PUNCT
bjp-81605	328	4	li	li	PROPN
bjp-81605	328	5	x	x	PROPN
bjp-81605	328	6	,	,	PUNCT
bjp-81605	328	7	song	song	NOUN
bjp-81605	328	8	d	d	PROPN
bjp-81605	328	9	,	,	PUNCT
bjp-81605	328	10	chen	chen	PROPN
bjp-81605	328	11	s	s	PROPN
bjp-81605	328	12	,	,	PUNCT
bjp-81605	328	13	zhang	zhang	PROPN
bjp-81605	328	14	z	z	PROPN
bjp-81605	328	15	,	,	PUNCT
bjp-81605	328	16	cao	cao	PROPN
bjp-81605	328	17	s	s	PROPN
bjp-81605	328	18	,	,	PUNCT
bjp-81605	328	19	liu	liu	PROPN
bjp-81605	328	20	m.	m.	PROPN
bjp-81605	328	21	atractylenolide	atractylenolide	PROPN
bjp-81605	328	22	iii	iii	PROPN
bjp-81605	328	23	induces	induce	NOUN
bjp-81605	328	24	apoptosis	apoptosis	NOUN
bjp-81605	328	25	by	by	ADP
bjp-81605	328	26	regulating	regulate	VERB
bjp-81605	328	27	the	the	DET
bjp-81605	328	28	bax/	bax/	NOUN
bjp-81605	328	29	bcl-2	bcl-2	VERB
bjp-81605	328	30	signaling	signal	VERB
bjp-81605	328	31	pathway	pathway	NOUN
bjp-81605	328	32	in	in	ADP
bjp-81605	328	33	human	human	ADJ
bjp-81605	328	34	colorectal	colorectal	ADJ
bjp-81605	328	35	cancer	cancer	NOUN
bjp-81605	328	36	hct116	hct116	PROPN
bjp-81605	328	37	cells	cell	NOUN
bjp-81605	328	38	in	in	ADP
bjp-81605	328	39	vitro	vitro	X
bjp-81605	328	40	and	and	CCONJ
bjp-81605	328	41	in	in	ADP
bjp-81605	328	42	vivo	vivo	NOUN
bjp-81605	328	43	.	.	PUNCT
bjp-81605	329	1	anti	anti	ADJ
bjp-81605	329	2	-	-	ADJ
bjp-81605	329	3	cancer	cancer	ADJ
bjp-81605	329	4	drugs	drug	NOUN
bjp-81605	329	5	.	.	PUNCT
bjp-81605	329	6	2021	2021	NUM
bjp-81605	329	7	;	;	PUNCT
bjp-81605	329	8	33	33	NUM
bjp-81605	329	9	:	:	SYM
bjp-81605	329	10	3047	3047	NUM
bjp-81605	329	11	.	.	PUNCT
bjp-81605	330	1	100	100	NUM
bjp-81605	330	2	bangladesh	bangladesh	PROPN
bjp-81605	330	3	j	j	PROPN
bjp-81605	330	4	pharmacol	pharmacol	PROPN
bjp-81605	330	5	2025	2025	NUM
bjp-81605	330	6	;	;	PUNCT
bjp-81605	330	7	20	20	NUM
bjp-81605	330	8	:	:	SYM
bjp-81605	330	9	89	89	NUM
bjp-81605	330	10	-	-	SYM
bjp-81605	330	11	100	100	NUM
bjp-81605	330	12	mailto:ramanathanm@psgpharma.ac.in	mailto:ramanathanm@psgpharma.ac.in	NOUN