id	sid	eid	entity	type
bptjm-28	1	1	berkeley pharma tech journal	ORG
bptjm-28	1	2	3	CARDINAL
bptjm-28	1	3	2022	CARDINAL
bptjm-28	1	4	june 8	DATE
bptjm-28	1	5	2022	CARDINAL
bptjm-28	1	6	july 19	DATE
bptjm-28	1	7	4.0	CARDINAL
bptjm-28	3	1	recent years	DATE
bptjm-28	6	1	venkata repakau	PERSON
bptjm-28	6	2	daniel lomboy	PERSON
bptjm-28	6	3	priscilla castro	PERSON
bptjm-28	6	4	i. background	PERSON
bptjm-28	8	1	30,000	CARDINAL
bptjm-28	8	2	the united states	GPE
bptjm-28	9	1	over half	CARDINAL
bptjm-28	9	2	around 60%	PERCENT
bptjm-28	10	1	four	CARDINAL
bptjm-28	11	1	three	CARDINAL
bptjm-28	13	1	50	CARDINAL
bptjm-28	14	1	5-40%	PERCENT
bptjm-28	15	1	1-5%	PERCENT
bptjm-28	16	1	1%	PERCENT
bptjm-28	16	2	individual5	PERSON
bptjm-28	17	1	proteins6	ORG
bptjm-28	19	1	factors7	PERSON
bptjm-28	24	1	one	CARDINAL
bptjm-28	25	1	one	CARDINAL
bptjm-28	25	2	berkeley pharma tech journal	ORG
bptjm-28	25	3	121	CARDINAL
bptjm-28	25	4	suggests8	PERSON
bptjm-28	26	1	one	CARDINAL
bptjm-28	31	1	alam et	PERSON
bptjm-28	32	1	al	PERSON
bptjm-28	34	1	two	CARDINAL
bptjm-28	34	2	viii9	PERSON
bptjm-28	35	1	von willebrand	PERSON
bptjm-28	39	1	nogami et.al	DATE
bptjm-28	39	2	372	PRODUCT
bptjm-28	42	1	sin berkeley pharma tech journal	ORG
bptjm-28	42	2	122	CARDINAL
bptjm-28	45	1	al12	PRODUCT
bptjm-28	46	1	sadiki	ORG
bptjm-28	52	1	jivi	PERSON
bptjm-28	56	1	two	CARDINAL
bptjm-28	56	2	two	CARDINAL
bptjm-28	56	3	weekly	DATE
bptjm-28	56	4	30-40	CARDINAL
bptjm-28	57	1	every 5 days	DATE
bptjm-28	57	2	weekly	DATE
bptjm-28	57	3	weekly	DATE
bptjm-28	58	1	total14	GPE
bptjm-28	59	1	berkeley pharma tech journal	ORG
bptjm-28	59	2	123	CARDINAL
bptjm-28	62	1	two	CARDINAL
bptjm-28	62	2	one	CARDINAL
bptjm-28	62	3	csas	GPE
bptjm-28	62	4	patient15	GPE
bptjm-28	65	1	aav gene	PERSON
bptjm-28	69	1	aav vector	PRODUCT
bptjm-28	72	1	berkeley pharma tech journal	ORG
bptjm-28	72	2	124	CARDINAL
bptjm-28	75	1	andari et.	ORG
bptjm-28	78	1	aav	ORG
bptjm-28	79	1	aav	ORG
bptjm-28	80	1	1	CARDINAL
bptjm-28	86	1	10	CARDINAL
bptjm-28	87	1	berkeley pharma tech journal	ORG
bptjm-28	87	2	125	CARDINAL
bptjm-28	91	1	20	CARDINAL
bptjm-28	92	1	2	CARDINAL
bptjm-28	93	1	joe	PERSON
bptjm-28	93	2	3.0	CARDINAL
bptjm-28	93	3	8/9	CARDINAL
bptjm-28	94	1	aav	PRODUCT
bptjm-28	94	2	nature21	ORG
bptjm-28	97	1	consider42	ORG
bptjm-28	98	1	9	CARDINAL
bptjm-28	98	2	8	CARDINAL
bptjm-28	99	1	berkeley pharma tech journal	ORG
bptjm-28	99	2	126	CARDINAL
bptjm-28	102	1	al	PERSON
bptjm-28	103	1	7 kb	PERCENT
bptjm-28	103	2	length21	GPE
bptjm-28	104	1	145	CARDINAL
bptjm-28	107	1	al	PERSON
bptjm-28	109	1	aav2	PERSON
bptjm-28	109	2	one	CARDINAL
bptjm-28	110	1	1	CARDINAL
bptjm-28	110	2	5	DATE
bptjm-28	110	3	4	CARDINAL
bptjm-28	111	1	8	CARDINAL
bptjm-28	111	2	2	CARDINAL
bptjm-28	111	3	aav	ORG
bptjm-28	111	4	8	CARDINAL
bptjm-28	112	1	20 weeks	DATE
bptjm-28	113	1	the 4 weeks	DATE
bptjm-28	113	2	75%	PERCENT
bptjm-28	113	3	the end of the 20 weeks	DATE
bptjm-28	114	1	10	CARDINAL
bptjm-28	117	1	nathwani berkeley pharma tech journal	ORG
bptjm-28	117	2	127	CARDINAL
bptjm-28	118	1	al	PERSON
bptjm-28	118	2	dimers24	PERSON
bptjm-28	119	1	20-fold	CARDINAL
bptjm-28	123	1	3	CARDINAL
bptjm-28	124	1	aav vector	PRODUCT
bptjm-28	125	1	uniqure25	ORG
bptjm-28	127	1	doshi et.	ORG
bptjm-28	128	1	berkeley pharma tech journal	ORG
bptjm-28	128	2	128	CARDINAL
bptjm-28	134	1	liver21	GPE
bptjm-28	136	1	al	PERSON
bptjm-28	137	1	the university of london	ORG
bptjm-28	137	2	raav2	PERSON
bptjm-28	140	1	doshi et	PERSON
bptjm-28	141	1	al	PERSON
bptjm-28	142	1	26	CARDINAL
bptjm-28	142	2	30-70%	PERCENT
bptjm-28	146	1	al	PERSON
bptjm-28	146	2	liver22	LOC
bptjm-28	148	1	berkeley pharma tech journal	ORG
bptjm-28	148	2	129	CARDINAL
bptjm-28	148	3	4	CARDINAL
bptjm-28	148	4	three	CARDINAL
bptjm-28	148	5	aav	PRODUCT
bptjm-28	150	1	two	CARDINAL
bptjm-28	150	2	one	CARDINAL
bptjm-28	151	1	two	CARDINAL
bptjm-28	153	1	al	PERSON
bptjm-28	153	2	2020	DATE
bptjm-28	153	3	response27	ORG
bptjm-28	154	1	second	ORDINAL
bptjm-28	157	1	pharma tech journal	ORG
bptjm-28	157	2	130	CARDINAL
bptjm-28	157	3	igg	ORG
bptjm-28	161	1	30	DATE
bptjm-28	163	1	1 year of age	DATE
bptjm-28	168	1	inhibitors32	GPE
bptjm-28	173	1	60-80%	PERCENT
bptjm-28	174	1	factors35	ORG
bptjm-28	175	1	berkeley pharma tech journal	ORG
bptjm-28	175	2	131	CARDINAL
bptjm-28	175	3	aav	PERSON
bptjm-28	177	1	al	PERSON
bptjm-28	178	1	2022	CARDINAL
bptjm-28	179	1	injection37	PERSON
bptjm-28	180	1	years	DATE
bptjm-28	189	1	half	CARDINAL
bptjm-28	191	1	berkeley pharma tech journal	ORG
bptjm-28	191	2	132	CARDINAL
bptjm-28	191	3	1	CARDINAL
bptjm-28	191	4	aav	PRODUCT
bptjm-28	193	1	aav	PERSON
bptjm-28	193	2	approximately 25	CARDINAL
bptjm-28	193	3	80	CARDINAL
bptjm-28	193	4	120	CARDINAL
bptjm-28	193	5	approximately 95	CARDINAL
bptjm-28	197	1	6 months	DATE
bptjm-28	197	2	experiment41	ORG
bptjm-28	198	1	aav	ORG
bptjm-28	198	2	kb	ORG
bptjm-28	198	3	approximately 8	CARDINAL
bptjm-28	199	1	8	CARDINAL
bptjm-28	206	1	aav	PRODUCT
bptjm-28	206	2	berkeley pharma tech journal	ORG
bptjm-28	206	3	133	CARDINAL
bptjm-28	207	1	aav	PRODUCT
bptjm-28	215	1	body18	ORG
bptjm-28	217	1	berkeley pharma tech journal	ORG
bptjm-28	217	2	134	CARDINAL
bptjm-28	217	3	1	CARDINAL
bptjm-28	218	1	nilsson	ORG
bptjm-28	218	2	berntorp e	ORG
bptjm-28	219	1	b. j	PERSON
bptjm-28	219	2	1992	DATE
bptjm-28	219	3	232	CARDINAL
bptjm-28	220	1	2	CARDINAL
bptjm-28	220	2	l.	PERSON
bptjm-28	220	3	j. m.	PERSON
bptjm-28	220	4	wright	PERSON
bptjm-28	220	5	j. f., & valentino	PERSON
bptjm-28	221	1	l. a.	PERSON
bptjm-28	221	2	2021	CARDINAL
bptjm-28	223	1	5(6	CARDINAL
bptjm-28	223	2	3	CARDINAL
bptjm-28	227	1	july 17, 2020	DATE
bptjm-28	228	1	march 29	DATE
bptjm-28	228	2	2022	DATE
bptjm-28	229	1	4	CARDINAL
bptjm-28	230	1	national hemophilia foundation	ORG
bptjm-28	231	1	https://www.hemophilia.org/bleeding-disorde	ORG
bptjm-28	232	1	march 29	DATE
bptjm-28	232	2	2022	CARDINAL
bptjm-28	233	1	5	CARDINAL
bptjm-28	234	1	indiana hemophilia & thrombosis center	ORG
bptjm-28	235	1	https://www.ihtc.org/severity-of-hemophilia	PERSON
bptjm-28	236	1	march 29	DATE
bptjm-28	236	2	2022	CARDINAL
bptjm-28	237	1	6	CARDINAL
bptjm-28	237	2	garagiola	PERSON
bptjm-28	238	1	j thromb haemost	PERSON
bptjm-28	239	1	2013;11	CARDINAL
bptjm-28	239	2	1:84-98	DATE
bptjm-28	240	1	doi:10.1111	ORG
bptjm-28	243	1	2013;4(1):59-72	CARDINAL
bptjm-28	244	1	8	CARDINAL
bptjm-28	245	1	arruda vr	PERSON
bptjm-28	247	1	2018;12:184-201	CARDINAL
bptjm-28	248	1	2018	DATE
bptjm-28	248	2	dec 31	DATE
bptjm-28	249	1	doi:10.1016	GPE
bptjm-28	249	2	9	CARDINAL
bptjm-28	250	1	alam	PERSON
bptjm-28	250	2	doshi h	ORG
bptjm-28	250	3	patel dn	PERSON
bptjm-28	250	4	patel k	PERSON
bptjm-28	250	5	36-year-old	DATE
bptjm-28	251	1	proc	PERSON
bptjm-28	251	2	bayl univ	ORG
bptjm-28	252	1	2021;35(1):93-95	CARDINAL
bptjm-28	253	1	2021	CARDINAL
bptjm-28	253	2	sep 15	DATE
bptjm-28	254	1	10	CARDINAL
bptjm-28	255	1	castaman g.	PERSON
bptjm-28	257	1	2011;9	CARDINAL
bptjm-28	257	2	2):s9	CARDINAL
bptjm-28	258	1	11	CARDINAL
bptjm-28	259	1	nogami k	PERSON
bptjm-28	259	2	zhou	PERSON
bptjm-28	259	3	wakabayashi h	ORG
bptjm-28	259	4	fay pj.	PERSON
bptjm-28	262	1	2005;105(11):4362-4368	DATE
bptjm-28	264	1	rachel m. lieser	PERSON
bptjm-28	264	2	daniel yur	PERSON
bptjm-28	264	3	millicent o. sullivan	PERSON
bptjm-28	264	4	wilfred chen	PERSON
bptjm-28	266	1	2020 31	DATE
bptjm-28	266	2	10	CARDINAL
bptjm-28	266	3	2272	CARDINAL
bptjm-28	267	1	10.1021	CARDINAL
bptjm-28	267	2	13	CARDINAL
bptjm-28	268	1	sadiki	ORG
bptjm-28	268	2	vaidya sr	PERSON
bptjm-28	270	1	2020;3(4):271-284	CARDINAL
bptjm-28	271	1	14	CARDINAL
bptjm-28	273	1	jivi us hcp	PERSON
bptjm-28	275	1	march 29	DATE
bptjm-28	275	2	2022	CARDINAL
bptjm-28	276	1	15	CARDINAL
bptjm-28	277	1	arruda vr	PERSON
bptjm-28	279	1	2018;12:184-201	CARDINAL
bptjm-28	280	1	2018	DATE
bptjm-28	280	2	dec 31	DATE
bptjm-28	281	1	doi:10.1016	GPE
bptjm-28	281	2	16	CARDINAL
bptjm-28	282	1	fisher pb	PERSON
bptjm-28	282	2	tew kd	PERSON
bptjm-28	282	3	chapter seven	LAW
bptjm-28	282	4	berkeley pharma tech journal	ORG
bptjm-28	282	5	135	CARDINAL
bptjm-28	284	1	amsterdam	GPE
bptjm-28	284	2	2012:221-263	CARDINAL
bptjm-28	285	1	17	CARDINAL
bptjm-28	285	2	kreuz s	PERSON
bptjm-28	285	3	2013	DATE
bptjm-28	285	4	1	CARDINAL
bptjm-28	285	5	2	DATE
bptjm-28	285	6	5	DATE
bptjm-28	285	7	6	DATE
bptjm-28	285	8	8	DATE
bptjm-28	286	1	plos	PERSON
bptjm-28	286	2	one 8(9	TIME
bptjm-28	287	1	18	CARDINAL
bptjm-28	288	1	el andari	PERSON
bptjm-28	288	2	j. and grimm	PERSON
bptjm-28	288	3	2021	CARDINAL
bptjm-28	289	1	biotechnol	GPE
bptjm-28	290	1	j.	PERSON
bptjm-28	290	2	16	CARDINAL
bptjm-28	290	3	2000025	CARDINAL
bptjm-28	291	1	https://doi.org/10.1002/biot.202000025 19	ORG
bptjm-28	293	1	diapharma	PERSON
bptjm-28	294	1	november 15, 2021	DATE
bptjm-28	295	1	march 29	DATE
bptjm-28	295	2	2022	CARDINAL
bptjm-28	296	1	20	CARDINAL
bptjm-28	299	1	march 29	DATE
bptjm-28	299	2	2022	CARDINAL
bptjm-28	300	1	21	CARDINAL
bptjm-28	301	1	nienhuis aw	PERSON
bptjm-28	301	2	nathwani ac	PERSON
bptjm-28	304	1	25	CARDINAL
bptjm-28	305	1	5th	ORDINAL
bptjm-28	305	2	2017:1163-1167	DATE
bptjm-28	306	1	22	CARDINAL
bptjm-28	307	1	sands m.s.	PERSON
bptjm-28	308	1	2012	DATE
bptjm-28	309	1	snyder r.	PERSON
bptjm-28	310	1	807	CARDINAL
bptjm-28	311	1	humana	ORG
bptjm-28	312	1	23	CARDINAL
bptjm-28	313	1	fisher kj	PERSON
bptjm-28	313	2	gao gp	PERSON
bptjm-28	313	3	weitzman md	PERSON
bptjm-28	313	4	burda jf	PERSON
bptjm-28	313	5	wilson jm.	PERSON
bptjm-28	315	1	1996;70(1):520-532	CARDINAL
bptjm-28	315	2	nathwani ac	PERSON
bptjm-28	315	3	gray jt	PERSON
bptjm-28	315	4	ng cy	PERSON
bptjm-28	317	1	2006;107(7):2653-2661	CARDINAL
bptjm-28	321	1	march 29	DATE
bptjm-28	321	2	2022	CARDINAL
bptjm-28	322	1	26	CARDINAL
bptjm-28	323	1	doshi bs	PERSON
bptjm-28	323	2	arruda vr.	PERSON
bptjm-28	325	1	september	DATE
bptjm-28	325	2	2018:273	CARDINAL
bptjm-28	326	1	27	CARDINAL
bptjm-28	327	1	g., chen	PERSON
bptjm-28	327	2	x.	GPE
bptjm-28	327	3	xie	PERSON
bptjm-28	327	4	zheng	PERSON
bptjm-28	327	5	q.	GPE
bptjm-28	327	6	xie	GPE
bptjm-28	327	7	j., yu	ORG
bptjm-28	327	8	f. x.	PERSON
bptjm-28	327	9	agbandje-mckenna	ORG
bptjm-28	327	10	m., srivastava, a., & ling	PERSON
bptjm-28	327	11	2020	DATE
bptjm-28	330	1	methods & clinical development	ORG
bptjm-28	330	2	17	CARDINAL
bptjm-28	330	3	545–555	CARDINAL
bptjm-28	331	1	28	CARDINAL
bptjm-28	332	1	j., kaspar	ORG
bptjm-28	332	2	b. et al	PERSON
bptjm-28	333	1	nat	ORG
bptjm-28	333	2	24	CARDINAL
bptjm-28	333	3	198–204	CARDINAL
bptjm-28	333	4	2006	DATE
bptjm-28	334	1	29	CARDINAL
bptjm-28	335	1	gouw sc	ORG
bptjm-28	335	2	van den berg	PERSON
bptjm-28	336	1	pharma tech journal	ORG
bptjm-28	336	2	136	CARDINAL
bptjm-28	337	1	semin thromb	PERSON
bptjm-28	338	1	2009;35(8):723-734	CARDINAL
bptjm-28	339	1	doi:10.1055/s-0029-1245105 30	ORG
bptjm-28	342	1	2013;4(1):59-72	CARDINAL
bptjm-28	343	1	31	CARDINAL
bptjm-28	344	1	lorenzo ji	PERSON
bptjm-28	344	2	aznar ja	PERSON
bptjm-28	345	1	british	NORP
bptjm-28	346	1	2001;113(3):600	CARDINAL
bptjm-28	347	1	doi:10.1046	GPE
bptjm-28	348	1	gouw sc	ORG
bptjm-28	348	2	van der bom jg	PERSON
bptjm-28	348	3	marijke van den	PERSON
bptjm-28	348	4	berg h.	PERSON
bptjm-28	351	1	2007;109(11):4648-4654	DATE
bptjm-28	353	1	louis jeune v	PERSON
bptjm-28	353	2	joergensen ja	PERSON
bptjm-28	353	3	hajjar rj	PERSON
bptjm-28	353	4	weber t. pre	PERSON
bptjm-28	355	1	2013;24(2):59-67	CARDINAL
bptjm-28	356	1	34	CARDINAL
bptjm-28	357	1	boutin s	PERSON
bptjm-28	357	2	monteilhet	PERSON
bptjm-28	357	3	veron p	ORG
bptjm-28	358	1	1	CARDINAL
bptjm-28	358	2	2	DATE
bptjm-28	358	3	5	DATE
bptjm-28	358	4	6	DATE
bptjm-28	358	5	8	DATE
bptjm-28	358	6	9	CARDINAL
bptjm-28	360	1	2010;21(6):704-712	CARDINAL
bptjm-28	360	2	35	CARDINAL
bptjm-28	361	1	patel sr	PERSON
bptjm-28	361	2	lundgren ts	ORG
bptjm-28	361	3	spencer ht	PERSON
bptjm-28	361	4	doering cb	PERSON
bptjm-28	365	1	36	CARDINAL
bptjm-28	366	1	song s	PERSON
bptjm-28	366	2	lyle mj	PERSON
bptjm-28	368	1	2022;27:916	CARDINAL
bptjm-28	369	1	2022	CARDINAL
bptjm-28	369	2	jan 10	DATE
bptjm-28	370	1	doi:10.1016	GPE
bptjm-28	371	1	37	CARDINAL
bptjm-28	371	2	27	CARDINAL
bptjm-28	371	3	2022	CARDINAL
bptjm-28	371	4	916-926	QUANTITY
bptjm-28	371	5	2162-2531	CARDINAL
bptjm-28	372	1	38	CARDINAL
bptjm-28	372	2	vandendruessche t	ORG
bptjm-28	372	3	acosta-sanchez	PERSON
bptjm-28	373	1	8 and 9	DATE
bptjm-28	374	1	j thromb haemost	PERSON
bptjm-28	375	1	2006;5(1):16	CARDINAL
bptjm-28	376	1	doi:10.1111	ORG
bptjm-28	376	2	7836.2006.02220.x 39	DATE
bptjm-28	377	1	arruda vr	PERSON
bptjm-28	379	1	2018;12:184-201	CARDINAL
bptjm-28	380	1	2018	DATE
bptjm-28	380	2	dec 31	DATE
bptjm-28	381	1	doi:10.1016	GPE
bptjm-28	381	2	40	CARDINAL
bptjm-28	382	1	tosolini ap	PERSON
bptjm-28	382	2	sleigh jn	PERSON
bptjm-28	382	3	2020	DATE
bptjm-28	384	1	neurosci	PERSON
bptjm-28	386	1	10.3389	CARDINAL
bptjm-28	386	2	41	CARDINAL
bptjm-28	387	1	wang	ORG
bptjm-28	387	2	z.	PERSON
bptjm-28	387	3	ma	PERSON
bptjm-28	387	4	li	PERSON
bptjm-28	387	5	j. et al	PERSON
bptjm-28	388	1	10	CARDINAL
bptjm-28	388	2	2105–2111	CARDINAL
bptjm-28	388	3	2003	DATE
bptjm-28	389	1	42	CARDINAL
bptjm-28	390	1	paul batty	PERSON
bptjm-28	390	2	david lillicrap	PERSON
bptjm-28	390	3	berkeley pharma tech journal	ORG
bptjm-28	390	4	137	CARDINAL
bptjm-28	390	5	28	CARDINAL
bptjm-28	390	6	october 2019	DATE
bptjm-28	390	7	r101	PERSON
bptjm-28	390	8	https://doi.org/10.1093/hmg/ddz157 43	DATE
bptjm-28	391	1	paul	PERSON
bptjm-28	391	2	lillicrap	PERSON
bptjm-28	391	3	david hemophilia	PERSON
bptjm-28	391	4	first	ORDINAL
bptjm-28	391	5	march 2021	DATE
bptjm-28	391	6	5	CARDINAL
bptjm-28	391	7	3	CARDINAL
bptjm-28	391	8	10.1097	CARDINAL
bptjm-28	391	9	44	CARDINAL
bptjm-28	392	1	111	DATE
bptjm-28	392	2	31–41	CARDINAL
bptjm-28	392	3	2020	DATE
bptjm-28	394	1	45	CARDINAL
bptjm-28	395	1	james w. larrick	PERSON
bptjm-28	395	2	m.d. ph.d.	PERSON
bptjm-28	395	3	april 27	DATE
bptjm-28	395	4	2022	CARDINAL
bptjm-28	396	1	berkeley pharma tech journal	ORG
bptjm-28	396	2	138	CARDINAL