id	sid	tid	token	lemma	pos
bptjm-16	1	1	inhibitors	inhibitor	NOUN
bptjm-16	1	2	of	of	ADP
bptjm-16	1	3	apoptosis	apoptosis	NOUN
bptjm-16	1	4	proteins	protein	NOUN
bptjm-16	1	5	as	as	ADP
bptjm-16	1	6	potential	potential	ADJ
bptjm-16	1	7	research	research	NOUN
bptjm-16	1	8	targets	target	NOUN
bptjm-16	1	9	for	for	ADP
bptjm-16	1	10	decoding	decode	VERB
bptjm-16	1	11	the	the	DET
bptjm-16	1	12	pathological	pathological	ADJ
bptjm-16	1	13	mechanisms	mechanism	NOUN
bptjm-16	1	14	of	of	ADP
bptjm-16	1	15	autoimmune	autoimmune	ADJ
bptjm-16	1	16	diseases	disease	NOUN
bptjm-16	1	17	by	by	ADP
bptjm-16	1	18	:	:	PUNCT
bptjm-16	1	19	kezia	kezia	PROPN
bptjm-16	1	20	philip	philip	PROPN
bptjm-16	1	21	,	,	PUNCT
bptjm-16	1	22	hoc	hoc	PROPN
bptjm-16	1	23	lan	lan	PROPN
bptjm-16	1	24	phung	phung	PROPN
bptjm-16	1	25	and	and	CCONJ
bptjm-16	1	26	vanloan	vanloan	PROPN
bptjm-16	1	27	nguyen	nguyen	PROPN
bptjm-16	1	28	berkeley	berkeley	PROPN
bptjm-16	1	29	pharma	pharma	PROPN
bptjm-16	1	30	tech	tech	PROPN
bptjm-16	1	31	journal	journal	NOUN
bptjm-16	1	32	of	of	ADP
bptjm-16	1	33	medicine	medicine	NOUN
bptjm-16	1	34	correspondence	correspondence	NOUN
bptjm-16	1	35	keziaphilip.bpt@gmail.com	keziaphilip.bpt@gmail.com	PROPN
bptjm-16	2	1	keywords	keyword	VERB
bptjm-16	2	2	apoptosis	apoptosis	NOUN
bptjm-16	2	3	necrosis	necrosis	NOUN
bptjm-16	2	4	necroptosis	necroptosis	NOUN
bptjm-16	2	5	autoimmune	autoimmune	ADJ
bptjm-16	2	6	diseases	disease	NOUN
bptjm-16	2	7	caspases	caspase	NOUN
bptjm-16	2	8	submitted	submit	VERB
bptjm-16	2	9	june	june	PROPN
bptjm-16	2	10	28	28	NUM
bptjm-16	2	11	,	,	PUNCT
bptjm-16	2	12	2021	2021	NUM
bptjm-16	2	13	accepted	accept	VERB
bptjm-16	2	14	august	august	PROPN
bptjm-16	2	15	20	20	NUM
bptjm-16	2	16	,	,	PUNCT
bptjm-16	2	17	2021	2021	NUM
bptjm-16	2	18	published	publish	VERB
bptjm-16	2	19	december	december	PROPN
bptjm-16	2	20	17	17	NUM
bptjm-16	2	21	,	,	PUNCT
bptjm-16	2	22	2021	2021	NUM
bptjm-16	2	23	full	full	ADJ
bptjm-16	2	24	open	open	ADJ
bptjm-16	2	25	access	access	NOUN
bptjm-16	2	26	creative	creative	ADJ
bptjm-16	2	27	commons	common	NOUN
bptjm-16	2	28	attribution	attribution	NOUN
bptjm-16	2	29	license	license	VERB
bptjm-16	2	30	4.0	4.0	NUM
bptjm-16	2	31	an	an	DET
bptjm-16	2	32	artist	artist	NOUN
bptjm-16	2	33	's	's	PART
bptjm-16	2	34	rendition	rendition	NOUN
bptjm-16	2	35	of	of	ADP
bptjm-16	2	36	a	a	DET
bptjm-16	2	37	cell	cell	NOUN
bptjm-16	2	38	undergoing	undergo	VERB
bptjm-16	2	39	apoptosis	apoptosis	NOUN
bptjm-16	2	40	.	.	PUNCT
bptjm-16	3	1	image	image	NOUN
bptjm-16	3	2	credits	credit	NOUN
bptjm-16	3	3	:	:	PUNCT
bptjm-16	3	4	kateryna	kateryna	PROPN
bptjm-16	3	5	kon	kon	PROPN
bptjm-16	3	6	/	/	SYM
bptjm-16	3	7	shutterstock.com	shutterstock.com	X
bptjm-16	3	8	abstract	abstract	ADJ
bptjm-16	3	9	necroptosis	necroptosis	NOUN
bptjm-16	3	10	,	,	PUNCT
bptjm-16	3	11	a	a	DET
bptjm-16	3	12	type	type	NOUN
bptjm-16	3	13	of	of	ADP
bptjm-16	3	14	pathological	pathological	ADJ
bptjm-16	3	15	and	and	CCONJ
bptjm-16	3	16	inflammatory	inflammatory	ADJ
bptjm-16	3	17	cell	cell	NOUN
bptjm-16	3	18	death	death	NOUN
bptjm-16	3	19	,	,	PUNCT
bptjm-16	3	20	resembles	resemble	VERB
bptjm-16	3	21	necrosis	necrosis	NOUN
bptjm-16	3	22	,	,	PUNCT
bptjm-16	3	23	the	the	DET
bptjm-16	3	24	termination	termination	NOUN
bptjm-16	3	25	of	of	ADP
bptjm-16	3	26	function	function	NOUN
bptjm-16	3	27	of	of	ADP
bptjm-16	3	28	a	a	DET
bptjm-16	3	29	bodily	bodily	ADJ
bptjm-16	3	30	tissue	tissue	NOUN
bptjm-16	3	31	,	,	PUNCT
bptjm-16	3	32	but	but	CCONJ
bptjm-16	3	33	adopts	adopt	VERB
bptjm-16	3	34	a	a	DET
bptjm-16	3	35	unique	unique	ADJ
bptjm-16	3	36	molecular	molecular	ADJ
bptjm-16	3	37	pathway	pathway	NOUN
bptjm-16	3	38	that	that	PRON
bptjm-16	3	39	is	be	AUX
bptjm-16	3	40	not	not	PART
bptjm-16	3	41	like	like	ADP
bptjm-16	3	42	apoptosis	apoptosis	NOUN
bptjm-16	3	43	,	,	PUNCT
bptjm-16	3	44	resulting	result	VERB
bptjm-16	3	45	in	in	ADP
bptjm-16	3	46	vastly	vastly	ADV
bptjm-16	3	47	different	different	ADJ
bptjm-16	3	48	immunological	immunological	ADJ
bptjm-16	3	49	consequences	consequence	NOUN
bptjm-16	3	50	.	.	PUNCT
bptjm-16	4	1	until	until	ADP
bptjm-16	4	2	recently	recently	ADV
bptjm-16	4	3	,	,	PUNCT
bptjm-16	4	4	necroptosis	necroptosis	NOUN
bptjm-16	4	5	was	be	AUX
bptjm-16	4	6	believed	believe	VERB
bptjm-16	4	7	to	to	PART
bptjm-16	4	8	mainly	mainly	ADV
bptjm-16	4	9	function	function	VERB
bptjm-16	4	10	as	as	ADP
bptjm-16	4	11	a	a	DET
bptjm-16	4	12	protective	protective	ADJ
bptjm-16	4	13	mechanism	mechanism	NOUN
bptjm-16	4	14	that	that	PRON
bptjm-16	4	15	counteracts	counteract	VERB
bptjm-16	4	16	the	the	DET
bptjm-16	4	17	viral	viral	ADJ
bptjm-16	4	18	barrier	barrier	NOUN
bptjm-16	4	19	of	of	ADP
bptjm-16	4	20	apoptosis	apoptosis	NOUN
bptjm-16	4	21	.	.	PUNCT
bptjm-16	5	1	however	however	ADV
bptjm-16	5	2	,	,	PUNCT
bptjm-16	5	3	mouse	mouse	PROPN
bptjm-16	5	4	model	model	NOUN
bptjm-16	5	5	studies	study	NOUN
bptjm-16	5	6	have	have	AUX
bptjm-16	5	7	indicated	indicate	VERB
bptjm-16	5	8	that	that	DET
bptjm-16	5	9	deficiency	deficiency	NOUN
bptjm-16	5	10	in	in	ADP
bptjm-16	5	11	elements	element	NOUN
bptjm-16	5	12	of	of	ADP
bptjm-16	5	13	the	the	DET
bptjm-16	5	14	apoptosis	apoptosis	NOUN
bptjm-16	5	15	machinery	machinery	NOUN
bptjm-16	5	16	such	such	ADJ
bptjm-16	5	17	as	as	ADP
bptjm-16	5	18	caspase-8	caspase-8	NOUN
bptjm-16	5	19	or	or	CCONJ
bptjm-16	5	20	fadd	fadd	NOUN
bptjm-16	5	21	can	can	AUX
bptjm-16	5	22	result	result	VERB
bptjm-16	5	23	in	in	ADP
bptjm-16	5	24	embryonic	embryonic	ADJ
bptjm-16	5	25	lethality	lethality	NOUN
bptjm-16	5	26	driven	drive	VERB
bptjm-16	5	27	by	by	ADP
bptjm-16	5	28	necroptosis	necroptosis	NOUN
bptjm-16	5	29	.	.	PUNCT
bptjm-16	6	1	previous	previous	ADJ
bptjm-16	6	2	studies	study	NOUN
bptjm-16	6	3	using	use	VERB
bptjm-16	6	4	conditional	conditional	ADJ
bptjm-16	6	5	depletion	depletion	NOUN
bptjm-16	6	6	of	of	ADP
bptjm-16	6	7	cellular	cellular	ADJ
bptjm-16	6	8	inhibitors	inhibitor	NOUN
bptjm-16	6	9	of	of	ADP
bptjm-16	6	10	apoptosis	apoptosis	NOUN
bptjm-16	6	11	(	(	PUNCT
bptjm-16	6	12	ciaps	ciaps	PROPN
bptjm-16	6	13	)	)	PUNCT
bptjm-16	6	14	revealed	reveal	VERB
bptjm-16	6	15	that	that	SCONJ
bptjm-16	6	16	the	the	DET
bptjm-16	6	17	necroptosis	necroptosis	NOUN
bptjm-16	6	18	pathway	pathway	NOUN
bptjm-16	6	19	is	be	AUX
bptjm-16	6	20	triggered	trigger	VERB
bptjm-16	6	21	under	under	ADP
bptjm-16	6	22	certain	certain	ADJ
bptjm-16	6	23	stressor	stressor	NOUN
bptjm-16	6	24	conditions	condition	NOUN
bptjm-16	6	25	.	.	PUNCT
bptjm-16	7	1	these	these	DET
bptjm-16	7	2	data	datum	NOUN
bptjm-16	7	3	support	support	VERB
bptjm-16	7	4	a	a	DET
bptjm-16	7	5	new	new	ADJ
bptjm-16	7	6	approach	approach	NOUN
bptjm-16	7	7	of	of	ADP
bptjm-16	7	8	targeting	target	VERB
bptjm-16	7	9	molecules	molecule	NOUN
bptjm-16	7	10	within	within	ADP
bptjm-16	7	11	the	the	DET
bptjm-16	7	12	cell	cell	NOUN
bptjm-16	7	13	death	death	NOUN
bptjm-16	7	14	pathways	pathway	NOUN
bptjm-16	7	15	to	to	PART
bptjm-16	7	16	identify	identify	VERB
bptjm-16	7	17	the	the	DET
bptjm-16	7	18	origin	origin	NOUN
bptjm-16	7	19	of	of	ADP
bptjm-16	7	20	autoimmune	autoimmune	ADJ
bptjm-16	7	21	diseases	disease	NOUN
bptjm-16	7	22	.	.	PUNCT
bptjm-16	8	1	hence	hence	ADV
bptjm-16	8	2	,	,	PUNCT
bptjm-16	8	3	distinguishing	distinguish	VERB
bptjm-16	8	4	between	between	ADP
bptjm-16	8	5	these	these	DET
bptjm-16	8	6	two	two	NUM
bptjm-16	8	7	types	type	NOUN
bptjm-16	8	8	of	of	ADP
bptjm-16	8	9	cell	cell	NOUN
bptjm-16	8	10	death	death	NOUN
bptjm-16	8	11	may	may	AUX
bptjm-16	8	12	prove	prove	VERB
bptjm-16	8	13	crucial	crucial	ADJ
bptjm-16	8	14	during	during	ADP
bptjm-16	8	15	pathologic	pathologic	ADJ
bptjm-16	8	16	evaluations	evaluation	NOUN
bptjm-16	8	17	.	.	PUNCT
bptjm-16	9	1	this	this	DET
bptjm-16	9	2	review	review	NOUN
bptjm-16	9	3	provides	provide	VERB
bptjm-16	9	4	a	a	DET
bptjm-16	9	5	detailed	detailed	ADJ
bptjm-16	9	6	insight	insight	NOUN
bptjm-16	9	7	into	into	ADP
bptjm-16	9	8	the	the	DET
bptjm-16	9	9	emerging	emerge	VERB
bptjm-16	9	10	discussion	discussion	NOUN
bptjm-16	9	11	on	on	ADP
bptjm-16	9	12	the	the	DET
bptjm-16	9	13	various	various	ADJ
bptjm-16	9	14	forms	form	NOUN
bptjm-16	9	15	of	of	ADP
bptjm-16	9	16	cell	cell	NOUN
bptjm-16	9	17	death	death	NOUN
bptjm-16	9	18	and	and	CCONJ
bptjm-16	9	19	the	the	DET
bptjm-16	9	20	essential	essential	ADJ
bptjm-16	9	21	roles	role	NOUN
bptjm-16	9	22	which	which	PRON
bptjm-16	9	23	certain	certain	ADJ
bptjm-16	9	24	molecules	molecule	NOUN
bptjm-16	9	25	play	play	VERB
bptjm-16	9	26	in	in	ADP
bptjm-16	9	27	the	the	DET
bptjm-16	9	28	development	development	NOUN
bptjm-16	9	29	and	and	CCONJ
bptjm-16	9	30	progression	progression	NOUN
bptjm-16	9	31	of	of	ADP
bptjm-16	9	32	autoimmune	autoimmune	ADJ
bptjm-16	9	33	diseases	disease	NOUN
bptjm-16	9	34	.	.	PUNCT
bptjm-16	10	1	armed	arm	VERB
bptjm-16	10	2	with	with	ADP
bptjm-16	10	3	this	this	DET
bptjm-16	10	4	knowledge	knowledge	NOUN
bptjm-16	10	5	,	,	PUNCT
bptjm-16	10	6	greater	great	ADJ
bptjm-16	10	7	efforts	effort	NOUN
bptjm-16	10	8	can	can	AUX
bptjm-16	10	9	be	be	AUX
bptjm-16	10	10	targeted	target	VERB
bptjm-16	10	11	towards	towards	ADP
bptjm-16	10	12	devising	devise	VERB
bptjm-16	10	13	more	more	ADV
bptjm-16	10	14	effective	effective	ADJ
bptjm-16	10	15	treatments	treatment	NOUN
bptjm-16	10	16	for	for	ADP
bptjm-16	10	17	interception	interception	NOUN
bptjm-16	10	18	of	of	ADP
bptjm-16	10	19	pathological	pathological	ADJ
bptjm-16	10	20	diseases	disease	NOUN
bptjm-16	10	21	,	,	PUNCT
bptjm-16	10	22	prior	prior	ADV
bptjm-16	10	23	to	to	ADP
bptjm-16	10	24	their	their	PRON
bptjm-16	10	25	uncontrollable	uncontrollable	ADJ
bptjm-16	10	26	progression	progression	NOUN
bptjm-16	10	27	.	.	PUNCT
bptjm-16	11	1	introduction	introduction	NOUN
bptjm-16	11	2	over	over	ADP
bptjm-16	11	3	the	the	DET
bptjm-16	11	4	last	last	ADJ
bptjm-16	11	5	decade	decade	NOUN
bptjm-16	11	6	,	,	PUNCT
bptjm-16	11	7	advances	advance	NOUN
bptjm-16	11	8	in	in	ADP
bptjm-16	11	9	cell	cell	NOUN
bptjm-16	11	10	death	death	NOUN
bptjm-16	11	11	research	research	NOUN
bptjm-16	11	12	have	have	AUX
bptjm-16	11	13	greatly	greatly	ADV
bptjm-16	11	14	contributed	contribute	VERB
bptjm-16	11	15	to	to	ADP
bptjm-16	11	16	our	our	PRON
bptjm-16	11	17	understanding	understanding	NOUN
bptjm-16	11	18	of	of	ADP
bptjm-16	11	19	cell	cell	NOUN
bptjm-16	11	20	death	death	NOUN
bptjm-16	11	21	.	.	PUNCT
bptjm-16	12	1	dysregulation	dysregulation	NOUN
bptjm-16	12	2	of	of	ADP
bptjm-16	12	3	cell	cell	NOUN
bptjm-16	12	4	death	death	NOUN
bptjm-16	12	5	has	have	AUX
bptjm-16	12	6	been	be	AUX
bptjm-16	12	7	found	find	VERB
bptjm-16	12	8	to	to	PART
bptjm-16	12	9	be	be	AUX
bptjm-16	12	10	critically	critically	ADV
bptjm-16	12	11	involved	involve	VERB
bptjm-16	12	12	in	in	ADP
bptjm-16	12	13	the	the	DET
bptjm-16	12	14	onset	onset	NOUN
bptjm-16	12	15	of	of	ADP
bptjm-16	12	16	various	various	ADJ
bptjm-16	12	17	human	human	ADJ
bptjm-16	12	18	diseases	disease	NOUN
bptjm-16	12	19	,	,	PUNCT
bptjm-16	12	20	such	such	ADJ
bptjm-16	12	21	as	as	ADP
bptjm-16	12	22	neurodegenerative	neurodegenerative	ADJ
bptjm-16	12	23	diseases1	diseases1	NOUN
bptjm-16	12	24	,	,	PUNCT
bptjm-16	12	25	autoimmune	autoimmune	ADJ
bptjm-16	12	26	diseases2	diseases2	PROPN
bptjm-16	12	27	,	,	PUNCT
bptjm-16	12	28	and	and	CCONJ
bptjm-16	12	29	cancer3	cancer3	PROPN
bptjm-16	12	30	.	.	PUNCT
bptjm-16	13	1	the	the	DET
bptjm-16	13	2	three	three	NUM
bptjm-16	13	3	forms	form	NOUN
bptjm-16	13	4	of	of	ADP
bptjm-16	13	5	cell	cell	NOUN
bptjm-16	13	6	death	death	NOUN
bptjm-16	13	7	of	of	ADP
bptjm-16	13	8	interest	interest	NOUN
bptjm-16	13	9	–	–	PUNCT
bptjm-16	13	10	apoptosis2,4,5,6	apoptosis2,4,5,6	NOUN
bptjm-16	13	11	,	,	PUNCT
bptjm-16	13	12	necrosis7,8,9	necrosis7,8,9	CCONJ
bptjm-16	13	13	,	,	PUNCT
bptjm-16	13	14	and	and	CCONJ
bptjm-16	13	15	necroptosis3,10	necroptosis3,10	PROPN
bptjm-16	13	16	–	–	PUNCT
bptjm-16	13	17	have	have	VERB
bptjm-16	13	18	distinct	distinct	ADJ
bptjm-16	13	19	features	feature	NOUN
bptjm-16	13	20	and	and	CCONJ
bptjm-16	13	21	activate	activate	VERB
bptjm-16	13	22	unique	unique	ADJ
bptjm-16	13	23	signaling	signal	VERB
bptjm-16	13	24	pathways	pathway	NOUN
bptjm-16	13	25	.	.	PUNCT
bptjm-16	14	1	apoptosis	apoptosis	NOUN
bptjm-16	14	2	is	be	AUX
bptjm-16	14	3	a	a	DET
bptjm-16	14	4	caspase	caspase	NOUN
bptjm-16	14	5	-	-	PUNCT
bptjm-16	14	6	mediated	mediate	VERB
bptjm-16	14	7	programmed	program	VERB
bptjm-16	14	8	cell	cell	NOUN
bptjm-16	14	9	death	death	NOUN
bptjm-16	14	10	that	that	PRON
bptjm-16	14	11	can	can	AUX
bptjm-16	14	12	be	be	AUX
bptjm-16	14	13	identi	identi	ADJ
bptjm-16	14	14	ed	ed	NOUN
bptjm-16	14	15	by	by	ADP
bptjm-16	14	16	chromosome	chromosome	NOUN
bptjm-16	14	17	condensation	condensation	NOUN
bptjm-16	14	18	,	,	PUNCT
bptjm-16	14	19	nuclear	nuclear	ADJ
bptjm-16	14	20	fragmentation	fragmentation	NOUN
bptjm-16	14	21	,	,	PUNCT
bptjm-16	14	22	and	and	CCONJ
bptjm-16	14	23	membrane	membrane	NOUN
bptjm-16	14	24	blebbing2	blebbing2	NOUN
bptjm-16	14	25	.	.	PUNCT
bptjm-16	15	1	conversely	conversely	ADV
bptjm-16	15	2	,	,	PUNCT
bptjm-16	15	3	necrosis	necrosis	NOUN
bptjm-16	15	4	is	be	AUX
bptjm-16	15	5	an	an	DET
bptjm-16	15	6	unregulated	unregulated	ADJ
bptjm-16	15	7	,	,	PUNCT
bptjm-16	15	8	accidental	accidental	ADJ
bptjm-16	15	9	form	form	NOUN
bptjm-16	15	10	of	of	ADP
bptjm-16	15	11	cell	cell	NOUN
bptjm-16	15	12	death	death	NOUN
bptjm-16	15	13	,	,	PUNCT
bptjm-16	15	14	triggered	trigger	VERB
bptjm-16	15	15	by	by	ADP
bptjm-16	15	16	non	non	ADJ
bptjm-16	15	17	-	-	ADJ
bptjm-16	15	18	physiological	physiological	ADJ
bptjm-16	15	19	stress	stress	NOUN
bptjm-16	15	20	inducers	inducer	NOUN
bptjm-16	15	21	and	and	CCONJ
bptjm-16	15	22	characterized	characterize	VERB
bptjm-16	15	23	by	by	ADP
bptjm-16	15	24	the	the	DET
bptjm-16	15	25	expansion	expansion	NOUN
bptjm-16	15	26	of	of	ADP
bptjm-16	15	27	cellular	cellular	ADJ
bptjm-16	15	28	organelles	organelle	NOUN
bptjm-16	15	29	,	,	PUNCT
bptjm-16	15	30	plasma	plasma	NOUN
bptjm-16	15	31	membrane	membrane	NOUN
bptjm-16	15	32	rupture	rupture	NOUN
bptjm-16	15	33	,	,	PUNCT
bptjm-16	15	34	and	and	CCONJ
bptjm-16	15	35	subsequent	subsequent	ADJ
bptjm-16	15	36	in	in	ADP
bptjm-16	15	37	ammatory	ammatory	NOUN
bptjm-16	15	38	responses	response	NOUN
bptjm-16	15	39	caused	cause	VERB
bptjm-16	15	40	by	by	ADP
bptjm-16	15	41	the	the	DET
bptjm-16	15	42	release	release	NOUN
bptjm-16	15	43	of	of	ADP
bptjm-16	15	44	the	the	DET
bptjm-16	15	45	intracellular	intracellular	ADJ
bptjm-16	15	46	contents7,8	contents7,8	PROPN
bptjm-16	15	47	.	.	PUNCT
bptjm-16	16	1	the	the	DET
bptjm-16	16	2	recent	recent	ADJ
bptjm-16	16	3	identi	identi	ADJ
bptjm-16	16	4	cation	cation	NOUN
bptjm-16	16	5	of	of	ADP
bptjm-16	16	6	necroptosis	necroptosis	NOUN
bptjm-16	16	7	has	have	AUX
bptjm-16	16	8	transformed	transform	VERB
bptjm-16	16	9	our	our	PRON
bptjm-16	16	10	understanding	understanding	NOUN
bptjm-16	16	11	of	of	ADP
bptjm-16	16	12	regulated	regulated	ADJ
bptjm-16	16	13	cell	cell	NOUN
bptjm-16	16	14	death	death	NOUN
bptjm-16	16	15	.	.	PUNCT
bptjm-16	17	1	it	it	PRON
bptjm-16	17	2	has	have	AUX
bptjm-16	17	3	become	become	VERB
bptjm-16	17	4	increasingly	increasingly	ADV
bptjm-16	17	5	evident	evident	ADJ
bptjm-16	17	6	that	that	SCONJ
bptjm-16	17	7	although	although	SCONJ
bptjm-16	17	8	the	the	DET
bptjm-16	17	9	di	di	NOUN
bptjm-16	17	10	erent	erent	NOUN
bptjm-16	17	11	types	type	NOUN
bptjm-16	17	12	of	of	ADP
bptjm-16	17	13	cell	cell	NOUN
bptjm-16	17	14	death	death	NOUN
bptjm-16	17	15	have	have	VERB
bptjm-16	17	16	distinctive	distinctive	ADJ
bptjm-16	17	17	characteristics	characteristic	NOUN
bptjm-16	17	18	,	,	PUNCT
bptjm-16	17	19	they	they	PRON
bptjm-16	17	20	are	be	AUX
bptjm-16	17	21	ultimately	ultimately	ADV
bptjm-16	17	22	interconnected	interconnect	VERB
bptjm-16	17	23	.	.	PUNCT
bptjm-16	18	1	thus	thus	ADV
bptjm-16	18	2	,	,	PUNCT
bptjm-16	18	3	the	the	DET
bptjm-16	18	4	activation	activation	NOUN
bptjm-16	18	5	or	or	CCONJ
bptjm-16	18	6	inhibition	inhibition	NOUN
bptjm-16	18	7	of	of	ADP
bptjm-16	18	8	a	a	DET
bptjm-16	18	9	particular	particular	ADJ
bptjm-16	18	10	signaling	signal	VERB
bptjm-16	18	11	molecular	molecular	ADJ
bptjm-16	18	12	pathway	pathway	NOUN
bptjm-16	18	13	under	under	ADP
bptjm-16	18	14	certain	certain	ADJ
bptjm-16	18	15	conditions	condition	NOUN
bptjm-16	18	16	determines	determine	VERB
bptjm-16	18	17	the	the	DET
bptjm-16	18	18	regulation	regulation	NOUN
bptjm-16	18	19	or	or	CCONJ
bptjm-16	18	20	dysregulation	dysregulation	NOUN
bptjm-16	18	21	of	of	ADP
bptjm-16	18	22	another	another	DET
bptjm-16	18	23	associated	associated	ADJ
bptjm-16	18	24	cell	cell	NOUN
bptjm-16	18	25	death	death	NOUN
bptjm-16	18	26	mechanism11,12,13,14	mechanism11,12,13,14	NOUN
bptjm-16	18	27	.	.	PUNCT
bptjm-16	19	1	in	in	ADP
bptjm-16	19	2	this	this	DET
bptjm-16	19	3	review	review	NOUN
bptjm-16	19	4	,	,	PUNCT
bptjm-16	19	5	we	we	PRON
bptjm-16	19	6	focus	focus	VERB
bptjm-16	19	7	on	on	ADP
bptjm-16	19	8	the	the	DET
bptjm-16	19	9	speci	speci	PROPN
bptjm-16	19	10	c	c	PROPN
bptjm-16	19	11	mechanisms	mechanism	NOUN
bptjm-16	19	12	involved	involve	VERB
bptjm-16	19	13	in	in	ADP
bptjm-16	19	14	each	each	DET
bptjm-16	19	15	particular	particular	ADJ
bptjm-16	19	16	type	type	NOUN
bptjm-16	19	17	of	of	ADP
bptjm-16	19	18	cell	cell	NOUN
bptjm-16	19	19	death	death	NOUN
bptjm-16	19	20	and	and	CCONJ
bptjm-16	19	21	the	the	DET
bptjm-16	19	22	connections	connection	NOUN
bptjm-16	19	23	between	between	ADP
bptjm-16	19	24	them	they	PRON
bptjm-16	19	25	.	.	PUNCT
bptjm-16	20	1	by	by	ADP
bptjm-16	20	2	highlighting	highlight	VERB
bptjm-16	20	3	the	the	DET
bptjm-16	20	4	pathophysiological	pathophysiological	ADJ
bptjm-16	20	5	relevance	relevance	NOUN
bptjm-16	20	6	of	of	ADP
bptjm-16	20	7	necroptosis	necroptosis	NOUN
bptjm-16	20	8	and	and	CCONJ
bptjm-16	20	9	the	the	DET
bptjm-16	20	10	key	key	ADJ
bptjm-16	20	11	roles	role	NOUN
bptjm-16	20	12	of	of	ADP
bptjm-16	20	13	certain	certain	ADJ
bptjm-16	20	14	cell	cell	NOUN
bptjm-16	20	15	mediators	mediator	NOUN
bptjm-16	20	16	and	and	CCONJ
bptjm-16	20	17	signaling	signal	VERB
bptjm-16	20	18	molecules	molecule	NOUN
bptjm-16	20	19	,	,	PUNCT
bptjm-16	20	20	we	we	PRON
bptjm-16	20	21	are	be	AUX
bptjm-16	20	22	proposing	propose	VERB
bptjm-16	20	23	a	a	DET
bptjm-16	20	24	new	new	ADJ
bptjm-16	20	25	perspective	perspective	NOUN
bptjm-16	20	26	for	for	ADP
bptjm-16	20	27	consequent	consequent	ADJ
bptjm-16	20	28	medical	medical	ADJ
bptjm-16	20	29	research	research	NOUN
bptjm-16	20	30	that	that	PRON
bptjm-16	20	31	investigates	investigate	VERB
bptjm-16	20	32	the	the	DET
bptjm-16	20	33	pathogenesis	pathogenesis	NOUN
bptjm-16	20	34	of	of	ADP
bptjm-16	20	35	various	various	ADJ
bptjm-16	20	36	diseases	disease	NOUN
bptjm-16	20	37	across	across	ADP
bptjm-16	20	38	the	the	DET
bptjm-16	20	39	body	body	NOUN
bptjm-16	20	40	,	,	PUNCT
bptjm-16	20	41	including	include	VERB
bptjm-16	20	42	neurological13,15	neurological13,15	NUM
bptjm-16	20	43	,	,	PUNCT
bptjm-16	20	44	cardiovascular16	cardiovascular16	ADJ
bptjm-16	20	45	,	,	PUNCT
bptjm-16	20	46	pulmonary	pulmonary	ADJ
bptjm-16	20	47	,	,	PUNCT
bptjm-16	20	48	gastrointestinal	gastrointestinal	ADJ
bptjm-16	20	49	,	,	PUNCT
bptjm-16	20	50	infectious	infectious	ADJ
bptjm-16	20	51	,	,	PUNCT
bptjm-16	20	52	and	and	CCONJ
bptjm-16	20	53	autoimmune3,17,18	autoimmune3,17,18	NOUN
bptjm-16	20	54	conditions	condition	NOUN
bptjm-16	20	55	,	,	PUNCT
bptjm-16	20	56	all	all	PRON
bptjm-16	20	57	of	of	ADP
bptjm-16	20	58	which	which	PRON
bptjm-16	20	59	have	have	AUX
bptjm-16	20	60	been	be	AUX
bptjm-16	20	61	linked	link	VERB
bptjm-16	20	62	to	to	ADP
bptjm-16	20	63	necroptosis	necroptosis	NOUN
bptjm-16	20	64	.	.	PUNCT
bptjm-16	21	1	cell	cell	NOUN
bptjm-16	21	2	death	death	NOUN
bptjm-16	21	3	and	and	CCONJ
bptjm-16	21	4	autoimmune	autoimmune	ADJ
bptjm-16	21	5	disorders	disorder	NOUN
bptjm-16	21	6	programmed	program	VERB
bptjm-16	21	7	cell	cell	NOUN
bptjm-16	21	8	death	death	NOUN
bptjm-16	21	9	is	be	AUX
bptjm-16	21	10	an	an	DET
bptjm-16	21	11	intricate	intricate	ADJ
bptjm-16	21	12	biological	biological	ADJ
bptjm-16	21	13	element	element	NOUN
bptjm-16	21	14	that	that	PRON
bptjm-16	21	15	plays	play	VERB
bptjm-16	21	16	a	a	DET
bptjm-16	21	17	vital	vital	ADJ
bptjm-16	21	18	role	role	NOUN
bptjm-16	21	19	in	in	ADP
bptjm-16	21	20	several	several	ADJ
bptjm-16	21	21	physiological	physiological	ADJ
bptjm-16	21	22	processes	process	NOUN
bptjm-16	21	23	,	,	PUNCT
bptjm-16	21	24	including	include	VERB
bptjm-16	21	25	homeostasis	homeostasis	NOUN
bptjm-16	21	26	,	,	PUNCT
bptjm-16	21	27	regulation	regulation	NOUN
bptjm-16	21	28	of	of	ADP
bptjm-16	21	29	the	the	DET
bptjm-16	21	30	immune	immune	ADJ
bptjm-16	21	31	system	system	NOUN
bptjm-16	21	32	,	,	PUNCT
bptjm-16	21	33	and	and	CCONJ
bptjm-16	21	34	disease	disease	NOUN
bptjm-16	21	35	pathogenesis1	pathogenesis1	VERB
bptjm-16	21	36	.	.	PUNCT
bptjm-16	22	1	it	it	PRON
bptjm-16	22	2	involves	involve	VERB
bptjm-16	22	3	multiple	multiple	ADJ
bptjm-16	22	4	pathways	pathway	NOUN
bptjm-16	22	5	and	and	CCONJ
bptjm-16	22	6	is	be	AUX
bptjm-16	22	7	regulated	regulate	VERB
bptjm-16	22	8	by	by	ADP
bptjm-16	22	9	various	various	ADJ
bptjm-16	22	10	intrinsic	intrinsic	ADJ
bptjm-16	22	11	cell	cell	NOUN
bptjm-16	22	12	death	death	NOUN
bptjm-16	22	13	programs	program	NOUN
bptjm-16	22	14	.	.	PUNCT
bptjm-16	23	1	over	over	ADP
bptjm-16	23	2	the	the	DET
bptjm-16	23	3	past	past	ADJ
bptjm-16	23	4	two	two	NUM
bptjm-16	23	5	decades	decade	NOUN
bptjm-16	23	6	,	,	PUNCT
bptjm-16	23	7	extensive	extensive	ADJ
bptjm-16	23	8	research	research	NOUN
bptjm-16	23	9	has	have	AUX
bptjm-16	23	10	transformed	transform	VERB
bptjm-16	23	11	the	the	DET
bptjm-16	23	12	understanding	understanding	NOUN
bptjm-16	23	13	of	of	ADP
bptjm-16	23	14	programmed	program	VERB
bptjm-16	23	15	cell	cell	NOUN
bptjm-16	23	16	death	death	NOUN
bptjm-16	23	17	and	and	CCONJ
bptjm-16	23	18	the	the	DET
bptjm-16	23	19	di	di	NOUN
bptjm-16	23	20	erent	erent	NOUN
bptjm-16	23	21	mechanisms	mechanism	NOUN
bptjm-16	23	22	that	that	PRON
bptjm-16	23	23	control	control	VERB
bptjm-16	23	24	it	it	PRON
bptjm-16	23	25	.	.	PUNCT
bptjm-16	24	1	berkeley	berkeley	PROPN
bptjm-16	24	2	pharma	pharma	PROPN
bptjm-16	24	3	tech	tech	PROPN
bptjm-16	24	4	journal	journal	NOUN
bptjm-16	24	5	of	of	ADP
bptjm-16	24	6	medicine	medicine	NOUN
bptjm-16	24	7	|	|	ADV
bptjm-16	24	8	96	96	NUM
bptjm-16	24	9	initially	initially	ADV
bptjm-16	24	10	,	,	PUNCT
bptjm-16	24	11	apoptosis	apoptosis	NOUN
bptjm-16	24	12	was	be	AUX
bptjm-16	24	13	believed	believe	VERB
bptjm-16	24	14	to	to	PART
bptjm-16	24	15	be	be	AUX
bptjm-16	24	16	the	the	DET
bptjm-16	24	17	only	only	ADJ
bptjm-16	24	18	form	form	NOUN
bptjm-16	24	19	of	of	ADP
bptjm-16	24	20	programmed	program	VERB
bptjm-16	24	21	cell	cell	NOUN
bptjm-16	24	22	death	death	NOUN
bptjm-16	24	23	,	,	PUNCT
bptjm-16	24	24	whereas	whereas	SCONJ
bptjm-16	24	25	necrosis	necrosis	NOUN
bptjm-16	24	26	was	be	AUX
bptjm-16	24	27	considered	consider	VERB
bptjm-16	24	28	unregulated	unregulated	ADJ
bptjm-16	24	29	and	and	CCONJ
bptjm-16	24	30	resulting	result	VERB
bptjm-16	24	31	from	from	ADP
bptjm-16	24	32	a	a	DET
bptjm-16	24	33	damaged	damage	VERB
bptjm-16	24	34	environmental	environmental	ADJ
bptjm-16	24	35	stress	stress	NOUN
bptjm-16	24	36	response3	response3	NOUN
bptjm-16	24	37	.	.	PUNCT
bptjm-16	25	1	however	however	ADV
bptjm-16	25	2	,	,	PUNCT
bptjm-16	25	3	emerging	emerge	VERB
bptjm-16	25	4	experimental	experimental	ADJ
bptjm-16	25	5	evidence	evidence	NOUN
bptjm-16	25	6	reveals	reveal	VERB
bptjm-16	25	7	a	a	DET
bptjm-16	25	8	regulated	regulated	ADJ
bptjm-16	25	9	form	form	NOUN
bptjm-16	25	10	of	of	ADP
bptjm-16	25	11	necrosis	necrosis	NOUN
bptjm-16	25	12	,	,	PUNCT
bptjm-16	25	13	termed	term	VERB
bptjm-16	25	14	necroptosis	necroptosis	NOUN
bptjm-16	25	15	,	,	PUNCT
bptjm-16	25	16	a	a	DET
bptjm-16	25	17	form	form	NOUN
bptjm-16	25	18	of	of	ADP
bptjm-16	25	19	cell	cell	NOUN
bptjm-16	25	20	death	death	NOUN
bptjm-16	25	21	controlled	control	VERB
bptjm-16	25	22	by	by	ADP
bptjm-16	25	23	speci	speci	PROPN
bptjm-16	25	24	c	c	PROPN
bptjm-16	25	25	intrinsic	intrinsic	ADJ
bptjm-16	25	26	programs	program	NOUN
bptjm-16	25	27	.	.	PUNCT
bptjm-16	26	1	autoimmune	autoimmune	ADJ
bptjm-16	26	2	disorders	disorder	NOUN
bptjm-16	26	3	,	,	PUNCT
bptjm-16	26	4	such	such	ADJ
bptjm-16	26	5	as	as	ADP
bptjm-16	26	6	rheumatoid	rheumatoid	NOUN
bptjm-16	26	7	arthritis	arthritis	NOUN
bptjm-16	26	8	,	,	PUNCT
bptjm-16	26	9	can	can	AUX
bptjm-16	26	10	result	result	VERB
bptjm-16	26	11	from	from	ADP
bptjm-16	26	12	defects	defect	NOUN
bptjm-16	26	13	in	in	ADP
bptjm-16	26	14	multiple	multiple	ADJ
bptjm-16	26	15	stages	stage	NOUN
bptjm-16	26	16	of	of	ADP
bptjm-16	26	17	these	these	DET
bptjm-16	26	18	forms	form	NOUN
bptjm-16	26	19	of	of	ADP
bptjm-16	26	20	cell	cell	NOUN
bptjm-16	26	21	death	death	NOUN
bptjm-16	26	22	,	,	PUNCT
bptjm-16	26	23	ranging	range	VERB
bptjm-16	26	24	from	from	ADP
bptjm-16	26	25	mutant	mutant	ADJ
bptjm-16	26	26	death	death	NOUN
bptjm-16	26	27	receptors	receptor	NOUN
bptjm-16	26	28	and	and	CCONJ
bptjm-16	26	29	ligands	ligand	NOUN
bptjm-16	26	30	to	to	ADP
bptjm-16	26	31	speci	speci	PROPN
bptjm-16	26	32	c	c	PROPN
bptjm-16	26	33	biochemical	biochemical	ADJ
bptjm-16	26	34	changes	change	NOUN
bptjm-16	26	35	in	in	ADP
bptjm-16	26	36	death	death	NOUN
bptjm-16	26	37	-	-	PUNCT
bptjm-16	26	38	inducing	induce	VERB
bptjm-16	26	39	signaling	signal	VERB
bptjm-16	26	40	molecules2	molecules2	NOUN
bptjm-16	26	41	.	.	PUNCT
bptjm-16	27	1	closely	closely	ADV
bptjm-16	27	2	examining	examine	VERB
bptjm-16	27	3	these	these	DET
bptjm-16	27	4	complex	complex	ADJ
bptjm-16	27	5	mechanisms	mechanism	NOUN
bptjm-16	27	6	is	be	AUX
bptjm-16	27	7	very	very	ADV
bptjm-16	27	8	essential	essential	ADJ
bptjm-16	27	9	in	in	ADP
bptjm-16	27	10	gaining	gain	VERB
bptjm-16	27	11	a	a	DET
bptjm-16	27	12	better	well	ADJ
bptjm-16	27	13	understanding	understanding	NOUN
bptjm-16	27	14	of	of	ADP
bptjm-16	27	15	the	the	DET
bptjm-16	27	16	pathogenesis	pathogenesis	NOUN
bptjm-16	27	17	of	of	ADP
bptjm-16	27	18	rheumatoid	rheumatoid	NOUN
bptjm-16	27	19	arthritis	arthritis	NOUN
bptjm-16	27	20	and	and	CCONJ
bptjm-16	27	21	several	several	ADJ
bptjm-16	27	22	other	other	ADJ
bptjm-16	27	23	autoimmune	autoimmune	ADJ
bptjm-16	27	24	disorders	disorder	NOUN
bptjm-16	27	25	.	.	PUNCT
bptjm-16	28	1	table	table	NOUN
bptjm-16	28	2	1	1	NUM
bptjm-16	28	3	:	:	PUNCT
bptjm-16	28	4	comparison	comparison	NOUN
bptjm-16	28	5	between	between	ADP
bptjm-16	28	6	morphological	morphological	ADJ
bptjm-16	28	7	features	feature	NOUN
bptjm-16	28	8	of	of	ADP
bptjm-16	28	9	apoptosis	apoptosis	NOUN
bptjm-16	28	10	,	,	PUNCT
bptjm-16	28	11	necrosis	necrosis	NOUN
bptjm-16	28	12	,	,	PUNCT
bptjm-16	28	13	and	and	CCONJ
bptjm-16	28	14	necroptosis	necroptosis	NOUN
bptjm-16	28	15	apoptosis	apoptosis	NOUN
bptjm-16	28	16	apoptosis	apoptosis	NOUN
bptjm-16	28	17	is	be	AUX
bptjm-16	28	18	an	an	DET
bptjm-16	28	19	intracellular	intracellular	ADJ
bptjm-16	28	20	process	process	NOUN
bptjm-16	28	21	that	that	PRON
bptjm-16	28	22	occurs	occur	VERB
bptjm-16	28	23	during	during	ADP
bptjm-16	28	24	cellular	cellular	ADJ
bptjm-16	28	25	development	development	NOUN
bptjm-16	28	26	,	,	PUNCT
bptjm-16	28	27	providing	provide	VERB
bptjm-16	28	28	a	a	DET
bptjm-16	28	29	homeostatic	homeostatic	ADJ
bptjm-16	28	30	mechanism	mechanism	NOUN
bptjm-16	28	31	to	to	PART
bptjm-16	28	32	remove	remove	VERB
bptjm-16	28	33	damaged	damaged	ADJ
bptjm-16	28	34	cells3,4,5,6	cells3,4,5,6	NOUN
bptjm-16	28	35	.	.	PUNCT
bptjm-16	29	1	cells	cell	NOUN
bptjm-16	29	2	undergoing	undergo	VERB
bptjm-16	29	3	apoptosis	apoptosis	NOUN
bptjm-16	29	4	display	display	NOUN
bptjm-16	29	5	morphological	morphological	ADJ
bptjm-16	29	6	characteristics	characteristic	NOUN
bptjm-16	29	7	such	such	ADJ
bptjm-16	29	8	as	as	ADP
bptjm-16	29	9	plasma	plasma	NOUN
bptjm-16	29	10	membrane	membrane	NOUN
bptjm-16	29	11	blebbing	blebbing	NOUN
bptjm-16	29	12	,	,	PUNCT
bptjm-16	29	13	chromosome	chromosome	NOUN
bptjm-16	29	14	condensation	condensation	NOUN
bptjm-16	29	15	,	,	PUNCT
bptjm-16	29	16	nuclear	nuclear	ADJ
bptjm-16	29	17	fragmentation	fragmentation	NOUN
bptjm-16	29	18	,	,	PUNCT
bptjm-16	29	19	formation	formation	NOUN
bptjm-16	29	20	of	of	ADP
bptjm-16	29	21	apoptotic	apoptotic	ADJ
bptjm-16	29	22	bodies	body	NOUN
bptjm-16	29	23	,	,	PUNCT
bptjm-16	29	24	and	and	CCONJ
bptjm-16	29	25	cell	cell	NOUN
bptjm-16	29	26	shrinkage	shrinkage	NOUN
bptjm-16	29	27	.	.	PUNCT
bptjm-16	30	1	in	in	ADP
bptjm-16	30	2	the	the	DET
bptjm-16	30	3	early	early	ADJ
bptjm-16	30	4	stages	stage	NOUN
bptjm-16	30	5	of	of	ADP
bptjm-16	30	6	the	the	DET
bptjm-16	30	7	disease	disease	NOUN
bptjm-16	30	8	,	,	PUNCT
bptjm-16	30	9	they	they	PRON
bptjm-16	30	10	also	also	ADV
bptjm-16	30	11	exhibit	exhibit	VERB
bptjm-16	30	12	biochemical	biochemical	ADJ
bptjm-16	30	13	changes	change	NOUN
bptjm-16	30	14	,	,	PUNCT
bptjm-16	30	15	such	such	ADJ
bptjm-16	30	16	as	as	ADP
bptjm-16	30	17	the	the	DET
bptjm-16	30	18	exposure	exposure	NOUN
bptjm-16	30	19	of	of	ADP
bptjm-16	30	20	phosphatidyl	phosphatidyl	NOUN
bptjm-16	30	21	-	-	PUNCT
bptjm-16	30	22	l	l	NOUN
bptjm-16	30	23	-	-	NOUN
bptjm-16	30	24	serine	serine	NOUN
bptjm-16	30	25	on	on	ADP
bptjm-16	30	26	the	the	DET
bptjm-16	30	27	outer	outer	ADJ
bptjm-16	30	28	plasma	plasma	NOUN
bptjm-16	30	29	membrane19,20,21	membrane19,20,21	ADJ
bptjm-16	30	30	.	.	PUNCT
bptjm-16	31	1	the	the	DET
bptjm-16	31	2	mechanism	mechanism	NOUN
bptjm-16	31	3	of	of	ADP
bptjm-16	31	4	apoptosis	apoptosis	NOUN
bptjm-16	31	5	involves	involve	VERB
bptjm-16	31	6	certain	certain	ADJ
bptjm-16	31	7	molecules	molecule	NOUN
bptjm-16	31	8	that	that	PRON
bptjm-16	31	9	play	play	VERB
bptjm-16	31	10	an	an	DET
bptjm-16	31	11	important	important	ADJ
bptjm-16	31	12	role	role	NOUN
bptjm-16	31	13	in	in	ADP
bptjm-16	31	14	mediating	mediate	VERB
bptjm-16	31	15	cell	cell	NOUN
bptjm-16	31	16	death	death	NOUN
bptjm-16	31	17	.	.	PUNCT
bptjm-16	32	1	apoptosis	apoptosis	NOUN
bptjm-16	32	2	involves	involve	VERB
bptjm-16	32	3	an	an	DET
bptjm-16	32	4	energy	energy	NOUN
bptjm-16	32	5	-	-	PUNCT
bptjm-16	32	6	dependent	dependent	ADJ
bptjm-16	32	7	cascade	cascade	NOUN
bptjm-16	32	8	of	of	ADP
bptjm-16	32	9	molecular	molecular	ADJ
bptjm-16	32	10	events	event	NOUN
bptjm-16	32	11	that	that	PRON
bptjm-16	32	12	results	result	VERB
bptjm-16	32	13	from	from	ADP
bptjm-16	32	14	three	three	NUM
bptjm-16	32	15	primary	primary	ADJ
bptjm-16	32	16	pathways	pathway	NOUN
bptjm-16	32	17	:	:	PUNCT
bptjm-16	32	18	the	the	DET
bptjm-16	32	19	extrinsic	extrinsic	ADJ
bptjm-16	32	20	(	(	PUNCT
bptjm-16	32	21	cell	cell	NOUN
bptjm-16	32	22	death	death	NOUN
bptjm-16	32	23	)	)	PUNCT
bptjm-16	32	24	receptor	receptor	NOUN
bptjm-16	32	25	berkeley	berkeley	PROPN
bptjm-16	32	26	pharma	pharma	PROPN
bptjm-16	32	27	tech	tech	NOUN
bptjm-16	32	28	journal	journal	NOUN
bptjm-16	32	29	of	of	ADP
bptjm-16	32	30	medicine	medicine	NOUN
bptjm-16	32	31	|	|	ADV
bptjm-16	32	32	97	97	NUM
bptjm-16	32	33	pathway	pathway	NOUN
bptjm-16	32	34	,	,	PUNCT
bptjm-16	32	35	the	the	DET
bptjm-16	32	36	intrinsic	intrinsic	ADJ
bptjm-16	32	37	(	(	PUNCT
bptjm-16	32	38	mitochondrial	mitochondrial	ADJ
bptjm-16	32	39	)	)	PUNCT
bptjm-16	32	40	pathway	pathway	NOUN
bptjm-16	32	41	,	,	PUNCT
bptjm-16	32	42	and	and	CCONJ
bptjm-16	32	43	the	the	DET
bptjm-16	32	44	stress	stress	NOUN
bptjm-16	32	45	-	-	PUNCT
bptjm-16	32	46	induced	induce	VERB
bptjm-16	32	47	pathway	pathway	NOUN
bptjm-16	32	48	in	in	ADP
bptjm-16	32	49	the	the	DET
bptjm-16	32	50	endoplasmic	endoplasmic	ADJ
bptjm-16	32	51	reticulum22	reticulum22	NOUN
bptjm-16	32	52	.	.	PUNCT
bptjm-16	33	1	despite	despite	SCONJ
bptjm-16	33	2	having	have	VERB
bptjm-16	33	3	di	di	NOUN
bptjm-16	33	4	erent	erent	NOUN
bptjm-16	33	5	initiator	initiator	NOUN
bptjm-16	33	6	caspases	caspase	NOUN
bptjm-16	33	7	(	(	PUNCT
bptjm-16	33	8	caspase-8	caspase-8	PROPN
bptjm-16	33	9	,	,	PUNCT
bptjm-16	33	10	caspase-9	caspase-9	PROPN
bptjm-16	33	11	,	,	PUNCT
bptjm-16	33	12	and	and	CCONJ
bptjm-16	33	13	caspase-10	caspase-10	PROPN
bptjm-16	33	14	)	)	PUNCT
bptjm-16	33	15	,	,	PUNCT
bptjm-16	33	16	all	all	PRON
bptjm-16	33	17	of	of	ADP
bptjm-16	33	18	these	these	DET
bptjm-16	33	19	pathways	pathway	NOUN
bptjm-16	33	20	are	be	AUX
bptjm-16	33	21	linked	link	VERB
bptjm-16	33	22	via	via	ADP
bptjm-16	33	23	caspase-3	caspase-3	NUM
bptjm-16	33	24	activation	activation	NOUN
bptjm-16	33	25	of	of	ADP
bptjm-16	33	26	downstream	downstream	ADJ
bptjm-16	33	27	molecules1	molecules1	NOUN
bptjm-16	33	28	.	.	PUNCT
bptjm-16	34	1	the	the	DET
bptjm-16	34	2	activation	activation	NOUN
bptjm-16	34	3	of	of	ADP
bptjm-16	34	4	the	the	DET
bptjm-16	34	5	death	death	NOUN
bptjm-16	34	6	receptor	receptor	NOUN
bptjm-16	34	7	-	-	PUNCT
bptjm-16	34	8	mediated	mediate	VERB
bptjm-16	34	9	apoptosis	apoptosis	NOUN
bptjm-16	34	10	pathway	pathway	NOUN
bptjm-16	34	11	occurs	occur	VERB
bptjm-16	34	12	when	when	SCONJ
bptjm-16	34	13	the	the	DET
bptjm-16	34	14	fas	fas	PROPN
bptjm-16	34	15	ligand	ligand	PROPN
bptjm-16	34	16	,	,	PUNCT
bptjm-16	34	17	tnf	tnf	PROPN
bptjm-16	34	18	-	-	PUNCT
bptjm-16	34	19	α	α	PROPN
bptjm-16	34	20	(	(	PUNCT
bptjm-16	34	21	tumor	tumor	NOUN
bptjm-16	34	22	necrosis	necrosis	NOUN
bptjm-16	34	23	factor	factor	NOUN
bptjm-16	34	24	α	α	NOUN
bptjm-16	34	25	)	)	PUNCT
bptjm-16	34	26	,	,	PUNCT
bptjm-16	34	27	binds	bind	VERB
bptjm-16	34	28	to	to	ADP
bptjm-16	34	29	the	the	DET
bptjm-16	34	30	corresponding	corresponding	ADJ
bptjm-16	34	31	death	death	NOUN
bptjm-16	34	32	receptors11,12	receptors11,12	NOUN
bptjm-16	34	33	.	.	PUNCT
bptjm-16	35	1	the	the	DET
bptjm-16	35	2	adaptor	adaptor	NOUN
bptjm-16	35	3	protein	protein	NOUN
bptjm-16	35	4	fadd11,23	fadd11,23	NOUN
bptjm-16	35	5	,	,	PUNCT
bptjm-16	35	6	and	and	CCONJ
bptjm-16	35	7	the	the	DET
bptjm-16	35	8	procaspase-8	procaspase-8	NUM
bptjm-16	35	9	protein	protein	NOUN
bptjm-16	35	10	form	form	NOUN
bptjm-16	35	11	a	a	DET
bptjm-16	35	12	complex	complex	NOUN
bptjm-16	35	13	,	,	PUNCT
bptjm-16	35	14	the	the	DET
bptjm-16	35	15	death	death	NOUN
bptjm-16	35	16	-	-	PUNCT
bptjm-16	35	17	inducing	induce	VERB
bptjm-16	35	18	signaling	signal	VERB
bptjm-16	35	19	complex	complex	ADJ
bptjm-16	35	20	(	(	PUNCT
bptjm-16	35	21	disc	disc	NOUN
bptjm-16	35	22	)	)	PUNCT
bptjm-16	35	23	,	,	PUNCT
bptjm-16	35	24	in	in	ADP
bptjm-16	35	25	which	which	PRON
bptjm-16	35	26	procaspase-8	procaspase-8	PRON
bptjm-16	35	27	is	be	AUX
bptjm-16	35	28	activated	activate	VERB
bptjm-16	35	29	by	by	ADP
bptjm-16	35	30	autohydrolysis24,25	autohydrolysis24,25	PROPN
bptjm-16	35	31	.	.	PUNCT
bptjm-16	36	1	the	the	DET
bptjm-16	36	2	activated	activate	VERB
bptjm-16	36	3	caspase-8	caspase-8	PROPN
bptjm-16	36	4	then	then	ADV
bptjm-16	36	5	transduces	transduce	VERB
bptjm-16	36	6	the	the	DET
bptjm-16	36	7	apoptosis	apoptosis	NOUN
bptjm-16	36	8	signal	signal	NOUN
bptjm-16	36	9	through	through	ADV
bptjm-16	36	10	,	,	PUNCT
bptjm-16	36	11	either	either	CCONJ
bptjm-16	36	12	the	the	DET
bptjm-16	36	13	activation	activation	NOUN
bptjm-16	36	14	of	of	ADP
bptjm-16	36	15	caspase-3	caspase-3	NUM
bptjm-16	36	16	,	,	PUNCT
bptjm-16	36	17	or	or	CCONJ
bptjm-16	36	18	the	the	DET
bptjm-16	36	19	cleavage	cleavage	NOUN
bptjm-16	36	20	of	of	ADP
bptjm-16	36	21	bid	bid	NOUN
bptjm-16	36	22	to	to	ADP
bptjm-16	36	23	truncated	truncated	ADJ
bptjm-16	36	24	bid	bid	NOUN
bptjm-16	36	25	(	(	PUNCT
bptjm-16	36	26	tbid	tbid	ADJ
bptjm-16	36	27	)	)	PUNCT
bptjm-16	36	28	.	.	PUNCT
bptjm-16	37	1	tbid	tbid	VERB
bptjm-16	37	2	translocates	translocate	NOUN
bptjm-16	37	3	to	to	ADP
bptjm-16	37	4	the	the	DET
bptjm-16	37	5	mitochondria	mitochondria	NOUN
bptjm-16	37	6	,	,	PUNCT
bptjm-16	37	7	resulting	result	VERB
bptjm-16	37	8	in	in	ADP
bptjm-16	37	9	conformational	conformational	ADJ
bptjm-16	37	10	changes	change	NOUN
bptjm-16	37	11	in	in	ADP
bptjm-16	37	12	bax	bax	PROPN
bptjm-16	37	13	and	and	CCONJ
bptjm-16	37	14	bak	bak	NOUN
bptjm-16	37	15	,	,	PUNCT
bptjm-16	37	16	as	as	ADV
bptjm-16	37	17	well	well	ADV
bptjm-16	37	18	as	as	ADP
bptjm-16	37	19	their	their	PRON
bptjm-16	37	20	oligomerization	oligomerization	NOUN
bptjm-16	37	21	for	for	ADP
bptjm-16	37	22	pore	pore	ADJ
bptjm-16	37	23	formation	formation	NOUN
bptjm-16	37	24	in	in	ADP
bptjm-16	37	25	the	the	DET
bptjm-16	37	26	outer	outer	ADJ
bptjm-16	37	27	mitochondrial	mitochondrial	ADJ
bptjm-16	37	28	membrane25,26	membrane25,26	NOUN
bptjm-16	37	29	.	.	PUNCT
bptjm-16	38	1	stress	stress	NOUN
bptjm-16	38	2	inducers	inducer	NOUN
bptjm-16	38	3	such	such	ADJ
bptjm-16	38	4	as	as	ADP
bptjm-16	38	5	dna	dna	PROPN
bptjm-16	38	6	damage	damage	NOUN
bptjm-16	38	7	,	,	PUNCT
bptjm-16	38	8	growth	growth	NOUN
bptjm-16	38	9	factor	factor	NOUN
bptjm-16	38	10	withdrawal	withdrawal	NOUN
bptjm-16	38	11	,	,	PUNCT
bptjm-16	38	12	and	and	CCONJ
bptjm-16	38	13	oxidative	oxidative	ADJ
bptjm-16	38	14	stress	stress	NOUN
bptjm-16	38	15	activate	activate	VERB
bptjm-16	38	16	the	the	DET
bptjm-16	38	17	mitochondrial	mitochondrial	ADJ
bptjm-16	38	18	-	-	PUNCT
bptjm-16	38	19	dependent	dependent	ADJ
bptjm-16	38	20	pathway27,28	pathway27,28	NOUN
bptjm-16	38	21	.	.	PUNCT
bptjm-16	39	1	this	this	DET
bptjm-16	39	2	intrinsic	intrinsic	ADJ
bptjm-16	39	3	pathway	pathway	NOUN
bptjm-16	39	4	is	be	AUX
bptjm-16	39	5	controlled	control	VERB
bptjm-16	39	6	by	by	ADP
bptjm-16	39	7	the	the	DET
bptjm-16	39	8	bcl-2	bcl-2	PUNCT
bptjm-16	39	9	family	family	NOUN
bptjm-16	39	10	of	of	ADP
bptjm-16	39	11	proteins	protein	NOUN
bptjm-16	39	12	,	,	PUNCT
bptjm-16	39	13	which	which	PRON
bptjm-16	39	14	regulates	regulate	VERB
bptjm-16	39	15	the	the	DET
bptjm-16	39	16	permeability	permeability	NOUN
bptjm-16	39	17	of	of	ADP
bptjm-16	39	18	the	the	DET
bptjm-16	39	19	outer	outer	ADJ
bptjm-16	39	20	mitochondrial	mitochondrial	ADJ
bptjm-16	39	21	membrane29,30,31	membrane29,30,31	NOUN
bptjm-16	39	22	.	.	PUNCT
bptjm-16	40	1	upon	upon	SCONJ
bptjm-16	40	2	release	release	NOUN
bptjm-16	40	3	into	into	ADP
bptjm-16	40	4	the	the	DET
bptjm-16	40	5	cytoplasm	cytoplasm	NOUN
bptjm-16	40	6	from	from	ADP
bptjm-16	40	7	the	the	DET
bptjm-16	40	8	mitochondria	mitochondria	NOUN
bptjm-16	40	9	,	,	PUNCT
bptjm-16	40	10	cytochrome	cytochrome	NOUN
bptjm-16	40	11	c	c	NOUN
bptjm-16	40	12	combines	combine	VERB
bptjm-16	40	13	with	with	ADP
bptjm-16	40	14	apaf-1	apaf-1	NUM
bptjm-16	40	15	to	to	PART
bptjm-16	40	16	promote	promote	VERB
bptjm-16	40	17	caspase-9	caspase-9	NUM
bptjm-16	40	18	activation	activation	NOUN
bptjm-16	40	19	,	,	PUNCT
bptjm-16	40	20	which	which	PRON
bptjm-16	40	21	,	,	PUNCT
bptjm-16	40	22	in	in	ADP
bptjm-16	40	23	turn	turn	NOUN
bptjm-16	40	24	,	,	PUNCT
bptjm-16	40	25	activates	activate	VERB
bptjm-16	40	26	e	e	PROPN
bptjm-16	40	27	ector	ector	PROPN
bptjm-16	40	28	caspases32,33	caspases32,33	PROPN
bptjm-16	40	29	to	to	PART
bptjm-16	40	30	trigger	trigger	VERB
bptjm-16	40	31	a	a	DET
bptjm-16	40	32	cascade	cascade	NOUN
bptjm-16	40	33	of	of	ADP
bptjm-16	40	34	proteolytic	proteolytic	ADJ
bptjm-16	40	35	events	event	NOUN
bptjm-16	40	36	.	.	PUNCT
bptjm-16	41	1	the	the	DET
bptjm-16	41	2	er	er	INTJ
bptjm-16	41	3	-	-	PUNCT
bptjm-16	41	4	dependent	dependent	ADJ
bptjm-16	41	5	pathway	pathway	NOUN
bptjm-16	41	6	is	be	AUX
bptjm-16	41	7	mediated	mediate	VERB
bptjm-16	41	8	by	by	ADP
bptjm-16	41	9	an	an	DET
bptjm-16	41	10	er	er	ADV
bptjm-16	41	11	-	-	PUNCT
bptjm-16	41	12	resistant	resistant	ADJ
bptjm-16	41	13	caspase	caspase	NOUN
bptjm-16	41	14	(	(	PUNCT
bptjm-16	41	15	caspase-12	caspase-12	PROPN
bptjm-16	41	16	)	)	PUNCT
bptjm-16	41	17	.	.	PUNCT
bptjm-16	42	1	it	it	PRON
bptjm-16	42	2	is	be	AUX
bptjm-16	42	3	activated	activate	VERB
bptjm-16	42	4	under	under	ADP
bptjm-16	42	5	the	the	DET
bptjm-16	42	6	presence	presence	NOUN
bptjm-16	42	7	of	of	ADP
bptjm-16	42	8	er	er	INTJ
bptjm-16	42	9	stresses	stress	NOUN
bptjm-16	42	10	:	:	PUNCT
bptjm-16	42	11	the	the	DET
bptjm-16	42	12	disturbance	disturbance	NOUN
bptjm-16	42	13	of	of	ADP
bptjm-16	42	14	calcium	calcium	NOUN
bptjm-16	42	15	homeostasis	homeostasis	NOUN
bptjm-16	42	16	,	,	PUNCT
bptjm-16	42	17	excessively	excessively	ADV
bptjm-16	42	18	unfolded	unfold	VERB
bptjm-16	42	19	or	or	CCONJ
bptjm-16	42	20	misfolded	misfolde	VERB
bptjm-16	42	21	protein	protein	NOUN
bptjm-16	42	22	accumulation	accumulation	NOUN
bptjm-16	42	23	,	,	PUNCT
bptjm-16	42	24	nutrient	nutrient	NOUN
bptjm-16	42	25	deprivation	deprivation	NOUN
bptjm-16	42	26	,	,	PUNCT
bptjm-16	42	27	and	and	CCONJ
bptjm-16	42	28	hypoxia22	hypoxia22	NOUN
bptjm-16	42	29	.	.	PUNCT
bptjm-16	43	1	activated	activate	VERB
bptjm-16	43	2	caspase-12	caspase-12	NOUN
bptjm-16	43	3	directly	directly	ADV
bptjm-16	43	4	cleaves	cleave	VERB
bptjm-16	43	5	caspase-9	caspase-9	PROPN
bptjm-16	43	6	after	after	ADP
bptjm-16	43	7	its	its	PRON
bptjm-16	43	8	translocation	translocation	NOUN
bptjm-16	43	9	from	from	ADP
bptjm-16	43	10	the	the	DET
bptjm-16	43	11	er	er	INTJ
bptjm-16	43	12	into	into	ADP
bptjm-16	43	13	the	the	DET
bptjm-16	43	14	cytosol	cytosol	NOUN
bptjm-16	43	15	,	,	PUNCT
bptjm-16	43	16	followed	follow	VERB
bptjm-16	43	17	by	by	ADP
bptjm-16	43	18	the	the	DET
bptjm-16	43	19	activation	activation	NOUN
bptjm-16	43	20	of	of	ADP
bptjm-16	43	21	caspase-334	caspase-334	NOUN
bptjm-16	43	22	.	.	PUNCT
bptjm-16	44	1	similarly	similarly	ADV
bptjm-16	44	2	,	,	PUNCT
bptjm-16	44	3	forming	form	VERB
bptjm-16	44	4	a	a	DET
bptjm-16	44	5	complex	complex	NOUN
bptjm-16	44	6	with	with	ADP
bptjm-16	44	7	the	the	DET
bptjm-16	44	8	inositol	inositol	NOUN
bptjm-16	44	9	requiring	require	VERB
bptjm-16	44	10	enzyme-1α	enzyme-1α	NOUN
bptjm-16	44	11	-	-	PUNCT
bptjm-16	44	12	tnf	tnf	PROPN
bptjm-16	44	13	receptor	receptor	NOUN
bptjm-16	44	14	-	-	PUNCT
bptjm-16	44	15	associated	associate	VERB
bptjm-16	44	16	factor	factor	NOUN
bptjm-16	44	17	2	2	NUM
bptjm-16	44	18	(	(	PUNCT
bptjm-16	44	19	traf2	traf2	PROPN
bptjm-16	44	20	)	)	PUNCT
bptjm-16	44	21	,	,	PUNCT
bptjm-16	44	22	or	or	CCONJ
bptjm-16	44	23	by	by	ADP
bptjm-16	44	24	calpains	calpain	NOUN
bptjm-16	44	25	,	,	PUNCT
bptjm-16	44	26	a	a	DET
bptjm-16	44	27	family	family	NOUN
bptjm-16	44	28	of	of	ADP
bptjm-16	44	29	ca2	ca2	PROPN
bptjm-16	44	30	+	+	PROPN
bptjm-16	44	31	-dependent	-dependent	ADJ
bptjm-16	44	32	intracellular	intracellular	ADJ
bptjm-16	44	33	cysteine	cysteine	NOUN
bptjm-16	44	34	proteases	protease	NOUN
bptjm-16	44	35	,	,	PUNCT
bptjm-16	44	36	activates	activate	VERB
bptjm-16	44	37	the	the	DET
bptjm-16	44	38	caspase-12	caspase-12	PROPN
bptjm-16	44	39	during	during	ADP
bptjm-16	44	40	er	er	INTJ
bptjm-16	44	41	stress.7,35	stress.7,35	NOUN
bptjm-16	44	42	.	.	PUNCT
bptjm-16	45	1	together	together	ADV
bptjm-16	45	2	,	,	PUNCT
bptjm-16	45	3	these	these	DET
bptjm-16	45	4	pathways	pathway	NOUN
bptjm-16	45	5	result	result	VERB
bptjm-16	45	6	in	in	ADP
bptjm-16	45	7	phagocytosis	phagocytosis	NOUN
bptjm-16	45	8	of	of	ADP
bptjm-16	45	9	the	the	DET
bptjm-16	45	10	apoptotic	apoptotic	ADJ
bptjm-16	45	11	bodies	body	NOUN
bptjm-16	45	12	by	by	ADP
bptjm-16	45	13	macrophages	macrophage	NOUN
bptjm-16	45	14	,	,	PUNCT
bptjm-16	45	15	neoplastic	neoplastic	ADJ
bptjm-16	45	16	cells	cell	NOUN
bptjm-16	45	17	,	,	PUNCT
bptjm-16	45	18	or	or	CCONJ
bptjm-16	45	19	neighboring	neighbor	VERB
bptjm-16	45	20	parenchymal	parenchymal	ADJ
bptjm-16	45	21	cells24	cells24	NOUN
bptjm-16	45	22	.	.	PUNCT
bptjm-16	46	1	interestingly	interestingly	ADV
bptjm-16	46	2	,	,	PUNCT
bptjm-16	46	3	caspase-3	caspase-3	NUM
bptjm-16	46	4	is	be	AUX
bptjm-16	46	5	the	the	DET
bptjm-16	46	6	common	common	ADJ
bptjm-16	46	7	factor	factor	NOUN
bptjm-16	46	8	linking	link	VERB
bptjm-16	46	9	these	these	DET
bptjm-16	46	10	3	3	NUM
bptjm-16	46	11	pathways	pathway	NOUN
bptjm-16	46	12	together	together	ADV
bptjm-16	46	13	,	,	PUNCT
bptjm-16	46	14	initiating	initiate	VERB
bptjm-16	46	15	the	the	DET
bptjm-16	46	16	apoptosis	apoptosis	NOUN
bptjm-16	46	17	execution	execution	NOUN
bptjm-16	46	18	pathway	pathway	NOUN
bptjm-16	46	19	upon	upon	SCONJ
bptjm-16	46	20	activation8	activation8	PROPN
bptjm-16	46	21	.	.	PUNCT
bptjm-16	47	1	this	this	DET
bptjm-16	47	2	marks	mark	VERB
bptjm-16	47	3	caspase-3	caspase-3	PUNCT
bptjm-16	47	4	as	as	ADP
bptjm-16	47	5	the	the	DET
bptjm-16	47	6	potential	potential	ADJ
bptjm-16	47	7	target	target	NOUN
bptjm-16	47	8	for	for	ADP
bptjm-16	47	9	studying	study	VERB
bptjm-16	47	10	the	the	DET
bptjm-16	47	11	divergence	divergence	NOUN
bptjm-16	47	12	of	of	ADP
bptjm-16	47	13	berkeley	berkeley	PROPN
bptjm-16	47	14	pharma	pharma	PROPN
bptjm-16	47	15	tech	tech	NOUN
bptjm-16	47	16	journal	journal	NOUN
bptjm-16	47	17	of	of	ADP
bptjm-16	47	18	medicine	medicine	NOUN
bptjm-16	47	19	|	|	ADV
bptjm-16	47	20	98	98	NUM
bptjm-16	47	21	each	each	DET
bptjm-16	47	22	pathway	pathway	NOUN
bptjm-16	47	23	,	,	PUNCT
bptjm-16	47	24	allowing	allow	VERB
bptjm-16	47	25	for	for	ADP
bptjm-16	47	26	the	the	DET
bptjm-16	47	27	manipulation	manipulation	NOUN
bptjm-16	47	28	of	of	ADP
bptjm-16	47	29	apoptosis	apoptosis	NOUN
bptjm-16	47	30	.	.	PUNCT
bptjm-16	48	1	understanding	understand	VERB
bptjm-16	48	2	the	the	DET
bptjm-16	48	3	morphological	morphological	ADJ
bptjm-16	48	4	and	and	CCONJ
bptjm-16	48	5	cellular	cellular	ADJ
bptjm-16	48	6	characteristics	characteristic	NOUN
bptjm-16	48	7	of	of	ADP
bptjm-16	48	8	apoptotic	apoptotic	ADJ
bptjm-16	48	9	mechanisms	mechanism	NOUN
bptjm-16	48	10	,	,	PUNCT
bptjm-16	48	11	as	as	ADV
bptjm-16	48	12	well	well	ADV
bptjm-16	48	13	as	as	ADP
bptjm-16	48	14	identifying	identify	VERB
bptjm-16	48	15	the	the	DET
bptjm-16	48	16	key	key	ADJ
bptjm-16	48	17	molecules	molecule	NOUN
bptjm-16	48	18	involved	involve	VERB
bptjm-16	48	19	in	in	ADP
bptjm-16	48	20	mediating	mediate	VERB
bptjm-16	48	21	cell	cell	NOUN
bptjm-16	48	22	death	death	NOUN
bptjm-16	48	23	,	,	PUNCT
bptjm-16	48	24	is	be	AUX
bptjm-16	48	25	integral	integral	ADJ
bptjm-16	48	26	in	in	ADP
bptjm-16	48	27	discerning	discern	VERB
bptjm-16	48	28	their	their	PRON
bptjm-16	48	29	roles	role	NOUN
bptjm-16	48	30	in	in	ADP
bptjm-16	48	31	autoimmune	autoimmune	ADJ
bptjm-16	48	32	diseases	disease	NOUN
bptjm-16	48	33	.	.	PUNCT
bptjm-16	49	1	figure	figure	NOUN
bptjm-16	49	2	1	1	NUM
bptjm-16	49	3	:	:	PUNCT
bptjm-16	49	4	mechanisms	mechanism	NOUN
bptjm-16	49	5	of	of	ADP
bptjm-16	49	6	apoptosis	apoptosis	NOUN
bptjm-16	49	7	table	table	NOUN
bptjm-16	49	8	2	2	NUM
bptjm-16	49	9	:	:	PUNCT
bptjm-16	49	10	names	name	NOUN
bptjm-16	49	11	and	and	CCONJ
bptjm-16	49	12	abbreviations	abbreviation	NOUN
bptjm-16	49	13	of	of	ADP
bptjm-16	49	14	proteins	protein	NOUN
bptjm-16	49	15	in	in	ADP
bptjm-16	49	16	the	the	DET
bptjm-16	49	17	extrinsic	extrinsic	ADJ
bptjm-16	49	18	,	,	PUNCT
bptjm-16	49	19	intrinsic	intrinsic	ADJ
bptjm-16	49	20	,	,	PUNCT
bptjm-16	49	21	and	and	CCONJ
bptjm-16	49	22	er	er	INTJ
bptjm-16	49	23	-	-	PUNCT
bptjm-16	49	24	dependent	dependent	ADJ
bptjm-16	49	25	pathways	pathway	NOUN
bptjm-16	49	26	of	of	ADP
bptjm-16	49	27	apoptosis	apoptosis	NOUN
bptjm-16	49	28	.	.	PUNCT
bptjm-16	50	1	berkeley	berkeley	PROPN
bptjm-16	50	2	pharma	pharma	PROPN
bptjm-16	50	3	tech	tech	PROPN
bptjm-16	50	4	journal	journal	NOUN
bptjm-16	50	5	of	of	ADP
bptjm-16	50	6	medicine	medicine	NOUN
bptjm-16	50	7	|	|	ADV
bptjm-16	50	8	99	99	NUM
bptjm-16	50	9	apoptosis	apoptosis	NOUN
bptjm-16	50	10	and	and	CCONJ
bptjm-16	50	11	disease	disease	NOUN
bptjm-16	50	12	the	the	DET
bptjm-16	50	13	repression	repression	NOUN
bptjm-16	50	14	of	of	ADP
bptjm-16	50	15	apoptosis	apoptosis	NOUN
bptjm-16	50	16	increases	increase	VERB
bptjm-16	50	17	the	the	DET
bptjm-16	50	18	possibility	possibility	NOUN
bptjm-16	50	19	of	of	ADP
bptjm-16	50	20	malignancy	malignancy	NOUN
bptjm-16	50	21	,	,	PUNCT
bptjm-16	50	22	as	as	SCONJ
bptjm-16	50	23	it	it	PRON
bptjm-16	50	24	inhibits	inhibit	VERB
bptjm-16	50	25	tumor	tumor	NOUN
bptjm-16	50	26	cell	cell	NOUN
bptjm-16	50	27	deaths	death	NOUN
bptjm-16	50	28	.	.	PUNCT
bptjm-16	51	1	on	on	ADP
bptjm-16	51	2	the	the	DET
bptjm-16	51	3	other	other	ADJ
bptjm-16	51	4	hand	hand	NOUN
bptjm-16	51	5	,	,	PUNCT
bptjm-16	51	6	uncontrolled	uncontrolled	ADJ
bptjm-16	51	7	apoptosis	apoptosis	NOUN
bptjm-16	51	8	is	be	AUX
bptjm-16	51	9	associated	associate	VERB
bptjm-16	51	10	with	with	ADP
bptjm-16	51	11	various	various	ADJ
bptjm-16	51	12	degenerative	degenerative	ADJ
bptjm-16	51	13	diseases	disease	NOUN
bptjm-16	51	14	including	include	VERB
bptjm-16	51	15	acquired	acquire	VERB
bptjm-16	51	16	immunode	immunode	ADJ
bptjm-16	51	17	ciency	ciency	NOUN
bptjm-16	51	18	syndrome36	syndrome36	NOUN
bptjm-16	51	19	,	,	PUNCT
bptjm-16	51	20	cancer2	cancer2	PROPN
bptjm-16	51	21	,	,	PUNCT
bptjm-16	51	22	parkinson	parkinson	NOUN
bptjm-16	51	23	's	's	PART
bptjm-16	51	24	disease37	disease37	NOUN
bptjm-16	51	25	and	and	CCONJ
bptjm-16	51	26	alzheimer	alzheimer	PROPN
bptjm-16	51	27	's	's	PART
bptjm-16	51	28	disease38	disease38	NOUN
bptjm-16	51	29	.	.	PUNCT
bptjm-16	52	1	additionally	additionally	ADV
bptjm-16	52	2	,	,	PUNCT
bptjm-16	52	3	apoptosis	apoptosis	NOUN
bptjm-16	52	4	has	have	AUX
bptjm-16	52	5	been	be	AUX
bptjm-16	52	6	correlated	correlate	VERB
bptjm-16	52	7	with	with	ADP
bptjm-16	52	8	hiv39	hiv39	NOUN
bptjm-16	52	9	,	,	PUNCT
bptjm-16	52	10	type	type	NOUN
bptjm-16	52	11	1	1	NUM
bptjm-16	52	12	diabetes41,42	diabetes41,42	NOUN
bptjm-16	52	13	,	,	PUNCT
bptjm-16	52	14	autoimmune	autoimmune	ADJ
bptjm-16	52	15	thyroid	thyroid	NOUN
bptjm-16	52	16	diseases	disease	NOUN
bptjm-16	52	17	,	,	PUNCT
bptjm-16	52	18	systemic	systemic	ADJ
bptjm-16	52	19	lupus	lupus	PROPN
bptjm-16	52	20	erythematosus	erythematosus	PROPN
bptjm-16	52	21	,	,	PUNCT
bptjm-16	52	22	rheumatoid	rheumatoid	NOUN
bptjm-16	52	23	arthritis	arthritis	NOUN
bptjm-16	52	24	,	,	PUNCT
bptjm-16	52	25	and	and	CCONJ
bptjm-16	52	26	sjogren	sjogren	NOUN
bptjm-16	52	27	’s	’s	PART
bptjm-16	52	28	syndrome	syndrome	NOUN
bptjm-16	52	29	.	.	PUNCT
bptjm-16	53	1	controlled	control	VERB
bptjm-16	53	2	apoptosis	apoptosis	NOUN
bptjm-16	53	3	regulates	regulate	VERB
bptjm-16	53	4	normal	normal	ADJ
bptjm-16	53	5	t	t	NOUN
bptjm-16	53	6	-	-	PUNCT
bptjm-16	53	7	cell	cell	NOUN
bptjm-16	53	8	selection	selection	NOUN
bptjm-16	53	9	and	and	CCONJ
bptjm-16	53	10	function	function	NOUN
bptjm-16	53	11	.	.	PUNCT
bptjm-16	54	1	in	in	ADP
bptjm-16	54	2	turn	turn	NOUN
bptjm-16	54	3	,	,	PUNCT
bptjm-16	54	4	type	type	NOUN
bptjm-16	54	5	1	1	NUM
bptjm-16	54	6	diabetes	diabetes	NOUN
bptjm-16	54	7	is	be	AUX
bptjm-16	54	8	caused	cause	VERB
bptjm-16	54	9	by	by	ADP
bptjm-16	54	10	the	the	DET
bptjm-16	54	11	insulin	insulin	NOUN
bptjm-16	54	12	-	-	PUNCT
bptjm-16	54	13	secreting	secrete	VERB
bptjm-16	54	14	β	β	NOUN
bptjm-16	54	15	-	-	NOUN
bptjm-16	54	16	cells	cell	NOUN
bptjm-16	54	17	of	of	ADP
bptjm-16	54	18	the	the	DET
bptjm-16	54	19	pancreas	pancreas	NOUN
bptjm-16	54	20	being	be	AUX
bptjm-16	54	21	attacked	attack	VERB
bptjm-16	54	22	by	by	ADP
bptjm-16	54	23	t	t	PROPN
bptjm-16	54	24	-	-	PUNCT
bptjm-16	54	25	cells	cell	NOUN
bptjm-16	54	26	.	.	PUNCT
bptjm-16	55	1	the	the	DET
bptjm-16	55	2	foxp3+cd4+cd25high	foxp3+cd4+cd25high	PROPN
bptjm-16	55	3	t	t	PROPN
bptjm-16	55	4	-	-	PUNCT
bptjm-16	55	5	cells	cell	NOUN
bptjm-16	55	6	(	(	PUNCT
bptjm-16	55	7	tregs	treg	NOUN
bptjm-16	55	8	)	)	PUNCT
bptjm-16	55	9	represent	represent	VERB
bptjm-16	55	10	one	one	NUM
bptjm-16	55	11	of	of	ADP
bptjm-16	55	12	the	the	DET
bptjm-16	55	13	best	good	ADJ
bptjm-16	55	14	characterized	characterize	VERB
bptjm-16	55	15	sub	sub	NOUN
bptjm-16	55	16	populations	population	NOUN
bptjm-16	55	17	of	of	ADP
bptjm-16	55	18	regulatory	regulatory	ADJ
bptjm-16	55	19	t	t	PROPN
bptjm-16	55	20	-	-	PUNCT
bptjm-16	55	21	cells	cell	NOUN
bptjm-16	55	22	that	that	PRON
bptjm-16	55	23	actively	actively	ADV
bptjm-16	55	24	suppress	suppress	VERB
bptjm-16	55	25	e	e	PROPN
bptjm-16	55	26	ector	ector	PROPN
bptjm-16	55	27	t	t	PROPN
bptjm-16	55	28	-	-	PUNCT
bptjm-16	55	29	cells	cell	NOUN
bptjm-16	55	30	.	.	PUNCT
bptjm-16	56	1	the	the	DET
bptjm-16	56	2	increasing	increase	VERB
bptjm-16	56	3	evidence	evidence	NOUN
bptjm-16	56	4	of	of	ADP
bptjm-16	56	5	tregs	treg	NOUN
bptjm-16	56	6	de	de	X
bptjm-16	56	7	ciency	ciency	NOUN
bptjm-16	56	8	in	in	ADP
bptjm-16	56	9	various	various	ADJ
bptjm-16	56	10	autoimmune	autoimmune	ADJ
bptjm-16	56	11	diseases3	diseases3	PROPN
bptjm-16	56	12	,	,	PUNCT
bptjm-16	56	13	as	as	ADV
bptjm-16	56	14	well	well	ADV
bptjm-16	56	15	as	as	ADP
bptjm-16	56	16	in	in	ADP
bptjm-16	56	17	type	type	NOUN
bptjm-16	56	18	1	1	NUM
bptjm-16	56	19	diabetes41,42	diabetes41,42	NOUN
bptjm-16	56	20	,	,	PUNCT
bptjm-16	56	21	suggests	suggest	VERB
bptjm-16	56	22	a	a	DET
bptjm-16	56	23	correlation	correlation	NOUN
bptjm-16	56	24	between	between	ADP
bptjm-16	56	25	greater	great	ADJ
bptjm-16	56	26	levels	level	NOUN
bptjm-16	56	27	of	of	ADP
bptjm-16	56	28	tregs	treg	NOUN
bptjm-16	56	29	apoptosis	apoptosis	NOUN
bptjm-16	56	30	and	and	CCONJ
bptjm-16	56	31	a	a	DET
bptjm-16	56	32	decline	decline	NOUN
bptjm-16	56	33	in	in	ADP
bptjm-16	56	34	suppressive	suppressive	ADJ
bptjm-16	56	35	potential	potential	NOUN
bptjm-16	56	36	of	of	ADP
bptjm-16	56	37	these	these	DET
bptjm-16	56	38	cells	cell	NOUN
bptjm-16	56	39	.	.	PUNCT
bptjm-16	57	1	however	however	ADV
bptjm-16	57	2	,	,	PUNCT
bptjm-16	57	3	the	the	DET
bptjm-16	57	4	data	datum	NOUN
bptjm-16	57	5	collected	collect	VERB
bptjm-16	57	6	are	be	AUX
bptjm-16	57	7	not	not	PART
bptjm-16	57	8	always	always	ADV
bptjm-16	57	9	consistent	consistent	ADJ
bptjm-16	57	10	in	in	ADP
bptjm-16	57	11	these	these	DET
bptjm-16	57	12	studies	study	NOUN
bptjm-16	57	13	since	since	SCONJ
bptjm-16	57	14	the	the	DET
bptjm-16	57	15	investigations	investigation	NOUN
bptjm-16	57	16	are	be	AUX
bptjm-16	57	17	conducted	conduct	VERB
bptjm-16	57	18	in	in	ADP
bptjm-16	57	19	di	di	NOUN
bptjm-16	57	20	erent	erent	NOUN
bptjm-16	57	21	phases	phase	NOUN
bptjm-16	57	22	of	of	ADP
bptjm-16	57	23	the	the	DET
bptjm-16	57	24	diseases	disease	NOUN
bptjm-16	57	25	and	and	CCONJ
bptjm-16	57	26	with	with	ADP
bptjm-16	57	27	various	various	ADJ
bptjm-16	57	28	ongoing	ongoing	ADJ
bptjm-16	57	29	immunosuppressive	immunosuppressive	ADJ
bptjm-16	57	30	therapies	therapy	NOUN
bptjm-16	57	31	.	.	PUNCT
bptjm-16	58	1	most	most	ADJ
bptjm-16	58	2	of	of	ADP
bptjm-16	58	3	these	these	DET
bptjm-16	58	4	studies	study	NOUN
bptjm-16	58	5	also	also	ADV
bptjm-16	58	6	have	have	VERB
bptjm-16	58	7	limitations	limitation	NOUN
bptjm-16	58	8	in	in	ADP
bptjm-16	58	9	terms	term	NOUN
bptjm-16	58	10	of	of	ADP
bptjm-16	58	11	distinguishing	distinguish	VERB
bptjm-16	58	12	ntreg	ntreg	NOUN
bptjm-16	58	13	cells	cell	NOUN
bptjm-16	58	14	from	from	ADP
bptjm-16	58	15	activated	activate	VERB
bptjm-16	58	16	te	te	ADP
bptjm-16	58	17	cells	cell	NOUN
bptjm-16	58	18	and	and	CCONJ
bptjm-16	58	19	characterizing	characterize	VERB
bptjm-16	58	20	their	their	PRON
bptjm-16	58	21	suppressive	suppressive	ADJ
bptjm-16	58	22	function	function	NOUN
bptjm-16	58	23	.	.	PUNCT
bptjm-16	59	1	current	current	ADJ
bptjm-16	59	2	studies	study	NOUN
bptjm-16	59	3	fail	fail	VERB
bptjm-16	59	4	to	to	PART
bptjm-16	59	5	elucidate	elucidate	VERB
bptjm-16	59	6	the	the	DET
bptjm-16	59	7	pathways	pathway	NOUN
bptjm-16	59	8	and	and	CCONJ
bptjm-16	59	9	genes	gene	NOUN
bptjm-16	59	10	that	that	PRON
bptjm-16	59	11	make	make	VERB
bptjm-16	59	12	tregs	treg	NOUN
bptjm-16	59	13	sensitive	sensitive	ADJ
bptjm-16	59	14	to	to	ADP
bptjm-16	59	15	apoptosis	apoptosis	VERB
bptjm-16	59	16	during	during	ADP
bptjm-16	59	17	the	the	DET
bptjm-16	59	18	progression	progression	NOUN
bptjm-16	59	19	of	of	ADP
bptjm-16	59	20	the	the	DET
bptjm-16	59	21	disease	disease	NOUN
bptjm-16	59	22	.	.	PUNCT
bptjm-16	60	1	recent	recent	ADJ
bptjm-16	60	2	evidence	evidence	NOUN
bptjm-16	60	3	supports	support	VERB
bptjm-16	60	4	the	the	DET
bptjm-16	60	5	involvement	involvement	NOUN
bptjm-16	60	6	of	of	ADP
bptjm-16	60	7	the	the	DET
bptjm-16	60	8	fas	fas	NOUN
bptjm-16	60	9	and	and	CCONJ
bptjm-16	60	10	trail	trail	NOUN
bptjm-16	60	11	mediated	mediate	VERB
bptjm-16	60	12	apoptotic	apoptotic	ADJ
bptjm-16	60	13	pathways	pathway	NOUN
bptjm-16	60	14	in	in	ADP
bptjm-16	60	15	the	the	DET
bptjm-16	60	16	autoimmune	autoimmune	ADJ
bptjm-16	60	17	diseases	disease	NOUN
bptjm-16	60	18	of	of	ADP
bptjm-16	60	19	the	the	DET
bptjm-16	60	20	thyroid17,18	thyroid17,18	NOUN
bptjm-16	60	21	.	.	PUNCT
bptjm-16	61	1	one	one	NUM
bptjm-16	61	2	of	of	ADP
bptjm-16	61	3	the	the	DET
bptjm-16	61	4	earliest	early	ADJ
bptjm-16	61	5	breakthroughs	breakthrough	NOUN
bptjm-16	61	6	occurred	occur	VERB
bptjm-16	61	7	when	when	SCONJ
bptjm-16	61	8	giordano	giordano	PROPN
bptjm-16	61	9	et	et	PROPN
bptjm-16	61	10	al	al	PROPN
bptjm-16	61	11	.	.	PROPN
bptjm-16	62	1	(	(	PUNCT
bptjm-16	62	2	1997	1997	NUM
bptjm-16	62	3	)	)	PUNCT
bptjm-16	62	4	used	use	VERB
bptjm-16	62	5	immunohistochemistry	immunohistochemistry	NOUN
bptjm-16	62	6	,	,	PUNCT
bptjm-16	62	7	ow	ow	NOUN
bptjm-16	62	8	cytometry	cytometry	NOUN
bptjm-16	62	9	,	,	PUNCT
bptjm-16	62	10	and	and	CCONJ
bptjm-16	62	11	rt	rt	NOUN
bptjm-16	62	12	-	-	PUNCT
bptjm-16	62	13	pcr	pcr	PROPN
bptjm-16	62	14	to	to	PART
bptjm-16	62	15	discover	discover	VERB
bptjm-16	62	16	the	the	DET
bptjm-16	62	17	constitutive	constitutive	ADJ
bptjm-16	62	18	expression	expression	NOUN
bptjm-16	62	19	of	of	ADP
bptjm-16	62	20	fasl	fasl	PROPN
bptjm-16	62	21	(	(	PUNCT
bptjm-16	62	22	fas	fas	PROPN
bptjm-16	62	23	ligand	ligand	PROPN
bptjm-16	62	24	)	)	PUNCT
bptjm-16	62	25	on	on	ADP
bptjm-16	62	26	normal	normal	ADJ
bptjm-16	62	27	and	and	CCONJ
bptjm-16	62	28	hashimoto	hashimoto	NOUN
bptjm-16	62	29	's	's	PART
bptjm-16	62	30	thyroiditis	thyroiditis	NOUN
bptjm-16	62	31	(	(	PUNCT
bptjm-16	62	32	ht	ht	NOUN
bptjm-16	62	33	)	)	PUNCT
bptjm-16	62	34	thyrocytes43,44	thyrocytes43,44	NOUN
bptjm-16	62	35	.	.	PUNCT
bptjm-16	63	1	although	although	SCONJ
bptjm-16	63	2	thyrocytes	thyrocyte	NOUN
bptjm-16	63	3	are	be	AUX
bptjm-16	63	4	known	know	VERB
bptjm-16	63	5	to	to	PART
bptjm-16	63	6	express	express	VERB
bptjm-16	63	7	the	the	DET
bptjm-16	63	8	death	death	NOUN
bptjm-16	63	9	receptor	receptor	NOUN
bptjm-16	63	10	fas	fas	NOUN
bptjm-16	63	11	,	,	PUNCT
bptjm-16	63	12	not	not	PART
bptjm-16	63	13	much	much	ADV
bptjm-16	63	14	is	be	AUX
bptjm-16	63	15	known	know	VERB
bptjm-16	63	16	about	about	ADP
bptjm-16	63	17	how	how	SCONJ
bptjm-16	63	18	the	the	DET
bptjm-16	63	19	expression	expression	NOUN
bptjm-16	63	20	is	be	AUX
bptjm-16	63	21	modulated	modulate	VERB
bptjm-16	63	22	.	.	PUNCT
bptjm-16	64	1	upregulation	upregulation	NOUN
bptjm-16	64	2	of	of	ADP
bptjm-16	64	3	fas	fas	PROPN
bptjm-16	64	4	was	be	AUX
bptjm-16	64	5	also	also	ADV
bptjm-16	64	6	found	find	VERB
bptjm-16	64	7	in	in	ADP
bptjm-16	64	8	the	the	DET
bptjm-16	64	9	thyrocytes	thyrocyte	NOUN
bptjm-16	64	10	of	of	ADP
bptjm-16	64	11	patients	patient	NOUN
bptjm-16	64	12	with	with	ADP
bptjm-16	64	13	graves	grave	NOUN
bptjm-16	64	14	’	’	PART
bptjm-16	64	15	disease	disease	NOUN
bptjm-16	64	16	.	.	PUNCT
bptjm-16	65	1	discoveries	discovery	NOUN
bptjm-16	65	2	like	like	ADP
bptjm-16	65	3	these	these	PRON
bptjm-16	65	4	strongly	strongly	ADV
bptjm-16	65	5	support	support	VERB
bptjm-16	65	6	the	the	DET
bptjm-16	65	7	theory	theory	NOUN
bptjm-16	65	8	that	that	SCONJ
bptjm-16	65	9	apoptosis	apoptosis	NOUN
bptjm-16	65	10	and	and	CCONJ
bptjm-16	65	11	the	the	DET
bptjm-16	65	12	proliferation	proliferation	NOUN
bptjm-16	65	13	of	of	ADP
bptjm-16	65	14	thyrocytes	thyrocyte	NOUN
bptjm-16	65	15	may	may	AUX
bptjm-16	65	16	be	be	AUX
bptjm-16	65	17	abnormally	abnormally	ADV
bptjm-16	65	18	accelerated	accelerate	VERB
bptjm-16	65	19	in	in	ADP
bptjm-16	65	20	patients	patient	NOUN
bptjm-16	65	21	with	with	ADP
bptjm-16	65	22	thyroid	thyroid	NOUN
bptjm-16	65	23	disease	disease	NOUN
bptjm-16	65	24	,	,	PUNCT
bptjm-16	65	25	although	although	SCONJ
bptjm-16	65	26	the	the	DET
bptjm-16	65	27	proliferation	proliferation	NOUN
bptjm-16	65	28	of	of	ADP
bptjm-16	65	29	thyrocytes	thyrocyte	NOUN
bptjm-16	65	30	may	may	AUX
bptjm-16	65	31	exceed	exceed	VERB
bptjm-16	65	32	their	their	PRON
bptjm-16	65	33	apoptosis	apoptosis	NOUN
bptjm-16	65	34	,	,	PUNCT
bptjm-16	65	35	which	which	PRON
bptjm-16	65	36	would	would	AUX
bptjm-16	65	37	result	result	VERB
bptjm-16	65	38	in	in	ADP
bptjm-16	65	39	hyperplasia	hyperplasia	NOUN
bptjm-16	65	40	.	.	PUNCT
bptjm-16	66	1	berkeley	berkeley	PROPN
bptjm-16	66	2	pharma	pharma	PROPN
bptjm-16	66	3	tech	tech	PROPN
bptjm-16	66	4	journal	journal	NOUN
bptjm-16	66	5	of	of	ADP
bptjm-16	66	6	medicine	medicine	NOUN
bptjm-16	66	7	|	|	ADV
bptjm-16	66	8	100	100	NUM
bptjm-16	66	9	another	another	DET
bptjm-16	66	10	autoimmune	autoimmune	ADJ
bptjm-16	66	11	disease	disease	NOUN
bptjm-16	66	12	,	,	PUNCT
bptjm-16	66	13	systemic	systemic	ADJ
bptjm-16	66	14	lupus	lupus	NOUN
bptjm-16	66	15	erythematosus	erythematosus	NOUN
bptjm-16	66	16	(	(	PUNCT
bptjm-16	66	17	sle	sle	PROPN
bptjm-16	66	18	)	)	PUNCT
bptjm-16	66	19	,	,	PUNCT
bptjm-16	66	20	is	be	AUX
bptjm-16	66	21	linked	link	VERB
bptjm-16	66	22	to	to	PART
bptjm-16	66	23	apoptosis	apoptosis	VERB
bptjm-16	66	24	through	through	ADP
bptjm-16	66	25	an	an	DET
bptjm-16	66	26	increased	increase	VERB
bptjm-16	66	27	number	number	NOUN
bptjm-16	66	28	of	of	ADP
bptjm-16	66	29	apoptotic	apoptotic	ADJ
bptjm-16	66	30	lymphocytes	lymphocyte	NOUN
bptjm-16	66	31	and	and	CCONJ
bptjm-16	66	32	macrophages	macrophage	NOUN
bptjm-16	66	33	observed	observe	VERB
bptjm-16	66	34	in	in	ADP
bptjm-16	66	35	patients	patient	NOUN
bptjm-16	66	36	with	with	ADP
bptjm-16	66	37	sle45	sle45	PROPN
bptjm-16	66	38	.	.	PUNCT
bptjm-16	67	1	characterized	characterize	VERB
bptjm-16	67	2	by	by	ADP
bptjm-16	67	3	the	the	DET
bptjm-16	67	4	declining	decline	VERB
bptjm-16	67	5	tolerance	tolerance	NOUN
bptjm-16	67	6	of	of	ADP
bptjm-16	67	7	self	self	NOUN
bptjm-16	67	8	-	-	PUNCT
bptjm-16	67	9	antigens	antigen	NOUN
bptjm-16	67	10	,	,	PUNCT
bptjm-16	67	11	this	this	DET
bptjm-16	67	12	disease	disease	NOUN
bptjm-16	67	13	causes	cause	VERB
bptjm-16	67	14	the	the	DET
bptjm-16	67	15	production	production	NOUN
bptjm-16	67	16	of	of	ADP
bptjm-16	67	17	antibodies	antibody	NOUN
bptjm-16	67	18	,	,	PUNCT
bptjm-16	67	19	reactive	reactive	ADJ
bptjm-16	67	20	with	with	ADP
bptjm-16	67	21	multiple	multiple	ADJ
bptjm-16	67	22	self	self	NOUN
bptjm-16	67	23	proteins46	proteins46	NOUN
bptjm-16	67	24	.	.	PUNCT
bptjm-16	68	1	apoptosis	apoptosis	NOUN
bptjm-16	68	2	is	be	AUX
bptjm-16	68	3	crucial	crucial	ADJ
bptjm-16	68	4	for	for	ADP
bptjm-16	68	5	regulating	regulate	VERB
bptjm-16	68	6	the	the	DET
bptjm-16	68	7	duration	duration	NOUN
bptjm-16	68	8	of	of	ADP
bptjm-16	68	9	immune	immune	ADJ
bptjm-16	68	10	responses	response	NOUN
bptjm-16	68	11	and	and	CCONJ
bptjm-16	68	12	maintaining	maintain	VERB
bptjm-16	68	13	the	the	DET
bptjm-16	68	14	diversity	diversity	NOUN
bptjm-16	68	15	of	of	ADP
bptjm-16	68	16	the	the	DET
bptjm-16	68	17	lymphoid	lymphoid	NOUN
bptjm-16	68	18	armamentarium	armamentarium	NOUN
bptjm-16	68	19	.	.	PUNCT
bptjm-16	69	1	based	base	VERB
bptjm-16	69	2	on	on	ADP
bptjm-16	69	3	considerable	considerable	ADJ
bptjm-16	69	4	statistical	statistical	ADJ
bptjm-16	69	5	data	datum	NOUN
bptjm-16	69	6	,	,	PUNCT
bptjm-16	69	7	studies	study	NOUN
bptjm-16	69	8	have	have	VERB
bptjm-16	69	9	identi	identi	NOUN
bptjm-16	69	10	ed	ed	NOUN
bptjm-16	69	11	that	that	SCONJ
bptjm-16	69	12	the	the	DET
bptjm-16	69	13	de	de	X
bptjm-16	69	14	ciency	ciency	NOUN
bptjm-16	69	15	of	of	ADP
bptjm-16	69	16	central	central	ADJ
bptjm-16	69	17	molecules	molecule	NOUN
bptjm-16	69	18	involved	involve	VERB
bptjm-16	69	19	in	in	ADP
bptjm-16	69	20	lymphocyte	lymphocyte	ADJ
bptjm-16	69	21	apoptosis	apoptosis	NOUN
bptjm-16	69	22	causes	cause	VERB
bptjm-16	69	23	lymphoproliferative	lymphoproliferative	ADJ
bptjm-16	69	24	and	and	CCONJ
bptjm-16	69	25	autoimmune	autoimmune	ADJ
bptjm-16	69	26	diseases	disease	NOUN
bptjm-16	69	27	in	in	ADP
bptjm-16	69	28	mice	mouse	NOUN
bptjm-16	69	29	and	and	CCONJ
bptjm-16	69	30	humans47,48	humans47,48	NOUN
bptjm-16	69	31	.	.	PUNCT
bptjm-16	70	1	in	in	ADP
bptjm-16	70	2	rheumatoid	rheumatoid	NOUN
bptjm-16	70	3	arthritis	arthritis	NOUN
bptjm-16	70	4	(	(	PUNCT
bptjm-16	70	5	ra	ra	NOUN
bptjm-16	70	6	)	)	PUNCT
bptjm-16	70	7	tissues	tissue	NOUN
bptjm-16	70	8	in	in	ADP
bptjm-16	70	9	vitro	vitro	X
bptjm-16	70	10	,	,	PUNCT
bptjm-16	70	11	synoviocytes	synoviocyte	NOUN
bptjm-16	70	12	,	,	PUNCT
bptjm-16	70	13	synovial	synovial	ADJ
bptjm-16	70	14	t	t	NOUN
bptjm-16	70	15	cells	cell	NOUN
bptjm-16	70	16	and	and	CCONJ
bptjm-16	70	17	macrophages	macrophage	NOUN
bptjm-16	70	18	have	have	AUX
bptjm-16	70	19	been	be	AUX
bptjm-16	70	20	found	find	VERB
bptjm-16	70	21	to	to	PART
bptjm-16	70	22	express	express	VERB
bptjm-16	70	23	high	high	ADJ
bptjm-16	70	24	levels	level	NOUN
bptjm-16	70	25	of	of	ADP
bptjm-16	70	26	fas	fas	PROPN
bptjm-16	70	27	and/or	and/or	CCONJ
bptjm-16	70	28	fasl	fasl	PROPN
bptjm-16	70	29	and	and	CCONJ
bptjm-16	70	30	are	be	AUX
bptjm-16	70	31	highly	highly	ADV
bptjm-16	70	32	susceptible	susceptible	ADJ
bptjm-16	70	33	to	to	ADP
bptjm-16	70	34	fas	fas	PROPN
bptjm-16	70	35	/	/	SYM
bptjm-16	70	36	fasl	fasl	NOUN
bptjm-16	70	37	-	-	PUNCT
bptjm-16	70	38	induced	induce	VERB
bptjm-16	70	39	apoptosis	apoptosis	NOUN
bptjm-16	70	40	.	.	PUNCT
bptjm-16	71	1	conversely	conversely	ADV
bptjm-16	71	2	,	,	PUNCT
bptjm-16	71	3	abnormalities	abnormality	NOUN
bptjm-16	71	4	in	in	ADP
bptjm-16	71	5	fas	fas	ADJ
bptjm-16	71	6	/	/	SYM
bptjm-16	71	7	fasl	fasl	NOUN
bptjm-16	71	8	expression	expression	NOUN
bptjm-16	71	9	and	and	CCONJ
bptjm-16	71	10	susceptibility	susceptibility	NOUN
bptjm-16	71	11	to	to	ADP
bptjm-16	71	12	fas	fas	VERB
bptjm-16	71	13	-	-	ADJ
bptjm-16	71	14	induced	induced	ADJ
bptjm-16	71	15	apoptosis	apoptosis	NOUN
bptjm-16	71	16	are	be	AUX
bptjm-16	71	17	generally	generally	ADV
bptjm-16	71	18	not	not	PART
bptjm-16	71	19	observed	observe	VERB
bptjm-16	71	20	in	in	ADP
bptjm-16	71	21	osteoarthritis49	osteoarthritis49	NOUN
bptjm-16	71	22	.	.	PUNCT
bptjm-16	72	1	in	in	ADP
bptjm-16	72	2	some	some	DET
bptjm-16	72	3	studies	study	NOUN
bptjm-16	72	4	,	,	PUNCT
bptjm-16	72	5	invading	invade	VERB
bptjm-16	72	6	t	t	NOUN
bptjm-16	72	7	cells	cell	NOUN
bptjm-16	72	8	have	have	AUX
bptjm-16	72	9	been	be	AUX
bptjm-16	72	10	observed	observe	VERB
bptjm-16	72	11	to	to	PART
bptjm-16	72	12	be	be	AUX
bptjm-16	72	13	defective	defective	ADJ
bptjm-16	72	14	in	in	ADP
bptjm-16	72	15	fasl	fasl	PROPN
bptjm-16	72	16	expression	expression	NOUN
bptjm-16	72	17	,	,	PUNCT
bptjm-16	72	18	which	which	PRON
bptjm-16	72	19	could	could	AUX
bptjm-16	72	20	explain	explain	VERB
bptjm-16	72	21	the	the	DET
bptjm-16	72	22	ine	ine	PROPN
bptjm-16	72	23	ective	ective	ADJ
bptjm-16	72	24	clearance	clearance	NOUN
bptjm-16	72	25	of	of	ADP
bptjm-16	72	26	activated	activated	ADJ
bptjm-16	72	27	(	(	PUNCT
bptjm-16	72	28	fas	fas	ADJ
bptjm-16	72	29	-	-	ADJ
bptjm-16	72	30	expressing	express	VERB
bptjm-16	72	31	)	)	PUNCT
bptjm-16	72	32	cells	cell	NOUN
bptjm-16	72	33	.	.	PUNCT
bptjm-16	73	1	additionally	additionally	ADV
bptjm-16	73	2	,	,	PUNCT
bptjm-16	73	3	rheumatoid	rheumatoid	NOUN
bptjm-16	73	4	synovial	synovial	ADJ
bptjm-16	73	5	uid	uid	PROPN
bptjm-16	73	6	contains	contain	VERB
bptjm-16	73	7	high	high	ADJ
bptjm-16	73	8	levels	level	NOUN
bptjm-16	73	9	of	of	ADP
bptjm-16	73	10	caspase-3	caspase-3	NUM
bptjm-16	73	11	inhibiting	inhibit	VERB
bptjm-16	73	12	nitric	nitric	ADJ
bptjm-16	73	13	oxide	oxide	NOUN
bptjm-16	73	14	.	.	PUNCT
bptjm-16	74	1	therefore	therefore	ADV
bptjm-16	74	2	,	,	PUNCT
bptjm-16	74	3	though	though	SCONJ
bptjm-16	74	4	these	these	DET
bptjm-16	74	5	studies	study	NOUN
bptjm-16	74	6	indicate	indicate	VERB
bptjm-16	74	7	that	that	SCONJ
bptjm-16	74	8	fas	fas	PROPN
bptjm-16	74	9	induced	induce	VERB
bptjm-16	74	10	apoptosis	apoptosis	NOUN
bptjm-16	74	11	is	be	AUX
bptjm-16	74	12	impaired	impair	VERB
bptjm-16	74	13	in	in	ADP
bptjm-16	74	14	ra	ra	PROPN
bptjm-16	74	15	joints	joint	NOUN
bptjm-16	74	16	,	,	PUNCT
bptjm-16	74	17	they	they	PRON
bptjm-16	74	18	do	do	AUX
bptjm-16	74	19	not	not	PART
bptjm-16	74	20	explain	explain	VERB
bptjm-16	74	21	whether	whether	SCONJ
bptjm-16	74	22	these	these	DET
bptjm-16	74	23	phenomena	phenomenon	NOUN
bptjm-16	74	24	are	be	AUX
bptjm-16	74	25	a	a	DET
bptjm-16	74	26	direct	direct	ADJ
bptjm-16	74	27	result	result	NOUN
bptjm-16	74	28	of	of	ADP
bptjm-16	74	29	the	the	DET
bptjm-16	74	30	initial	initial	NOUN
bptjm-16	74	31	in	in	ADP
bptjm-16	74	32	ammatory	ammatory	ADJ
bptjm-16	74	33	pathways	pathway	NOUN
bptjm-16	74	34	of	of	ADP
bptjm-16	74	35	ra	ra	PROPN
bptjm-16	74	36	or	or	CCONJ
bptjm-16	74	37	whether	whether	SCONJ
bptjm-16	74	38	they	they	PRON
bptjm-16	74	39	underlie	underlie	VERB
bptjm-16	74	40	the	the	DET
bptjm-16	74	41	disease	disease	NOUN
bptjm-16	74	42	etiology	etiology	NOUN
bptjm-16	74	43	.	.	PUNCT
bptjm-16	75	1	apoptosis	apoptosis	NOUN
bptjm-16	75	2	evidently	evidently	ADV
bptjm-16	75	3	plays	play	VERB
bptjm-16	75	4	a	a	DET
bptjm-16	75	5	valuable	valuable	ADJ
bptjm-16	75	6	role	role	NOUN
bptjm-16	75	7	in	in	ADP
bptjm-16	75	8	the	the	DET
bptjm-16	75	9	pathogenesis	pathogenesis	NOUN
bptjm-16	75	10	of	of	ADP
bptjm-16	75	11	several	several	ADJ
bptjm-16	75	12	of	of	ADP
bptjm-16	75	13	the	the	DET
bptjm-16	75	14	autoimmune	autoimmune	ADJ
bptjm-16	75	15	diseases	disease	NOUN
bptjm-16	75	16	.	.	PUNCT
bptjm-16	76	1	the	the	DET
bptjm-16	76	2	extent	extent	NOUN
bptjm-16	76	3	of	of	ADP
bptjm-16	76	4	apoptotic	apoptotic	ADJ
bptjm-16	76	5	regulation	regulation	NOUN
bptjm-16	76	6	dictates	dictate	VERB
bptjm-16	76	7	the	the	DET
bptjm-16	76	8	pathological	pathological	ADJ
bptjm-16	76	9	manifestations	manifestation	NOUN
bptjm-16	76	10	of	of	ADP
bptjm-16	76	11	these	these	DET
bptjm-16	76	12	diseases	disease	NOUN
bptjm-16	76	13	.	.	PUNCT
bptjm-16	77	1	considerably	considerably	ADV
bptjm-16	77	2	repressed	repress	VERB
bptjm-16	77	3	apoptosis	apoptosis	NOUN
bptjm-16	77	4	increases	increase	VERB
bptjm-16	77	5	the	the	DET
bptjm-16	77	6	likelihood	likelihood	NOUN
bptjm-16	77	7	of	of	ADP
bptjm-16	77	8	malignancy	malignancy	NOUN
bptjm-16	77	9	,	,	PUNCT
bptjm-16	77	10	whereas	whereas	SCONJ
bptjm-16	77	11	unregulated	unregulated	ADJ
bptjm-16	77	12	apoptosis	apoptosis	NOUN
bptjm-16	77	13	can	can	AUX
bptjm-16	77	14	directly	directly	ADV
bptjm-16	77	15	lead	lead	VERB
bptjm-16	77	16	to	to	ADP
bptjm-16	77	17	the	the	DET
bptjm-16	77	18	initiation	initiation	NOUN
bptjm-16	77	19	and	and	CCONJ
bptjm-16	77	20	progressions	progression	NOUN
bptjm-16	77	21	of	of	ADP
bptjm-16	77	22	several	several	ADJ
bptjm-16	77	23	autoimmune	autoimmune	ADJ
bptjm-16	77	24	diseases	disease	NOUN
bptjm-16	77	25	.	.	PUNCT
bptjm-16	78	1	the	the	DET
bptjm-16	78	2	exact	exact	ADJ
bptjm-16	78	3	molecules	molecule	NOUN
bptjm-16	78	4	and	and	CCONJ
bptjm-16	78	5	cellular	cellular	ADJ
bptjm-16	78	6	targets	target	NOUN
bptjm-16	78	7	determine	determine	VERB
bptjm-16	78	8	the	the	DET
bptjm-16	78	9	type	type	NOUN
bptjm-16	78	10	of	of	ADP
bptjm-16	78	11	degenerative	degenerative	ADJ
bptjm-16	78	12	disease	disease	NOUN
bptjm-16	78	13	.	.	PUNCT
bptjm-16	79	1	thus	thus	ADV
bptjm-16	79	2	,	,	PUNCT
bptjm-16	79	3	studies	study	NOUN
bptjm-16	79	4	discovering	discover	VERB
bptjm-16	79	5	the	the	DET
bptjm-16	79	6	functions	function	NOUN
bptjm-16	79	7	and	and	CCONJ
bptjm-16	79	8	mechanisms	mechanism	NOUN
bptjm-16	79	9	of	of	ADP
bptjm-16	79	10	cell	cell	NOUN
bptjm-16	79	11	mediators	mediator	NOUN
bptjm-16	79	12	involved	involve	VERB
bptjm-16	79	13	in	in	ADP
bptjm-16	79	14	cell	cell	NOUN
bptjm-16	79	15	death	death	NOUN
bptjm-16	79	16	are	be	AUX
bptjm-16	79	17	crucial	crucial	ADJ
bptjm-16	79	18	to	to	ADP
bptjm-16	79	19	elucidating	elucidate	VERB
bptjm-16	79	20	the	the	DET
bptjm-16	79	21	pathogenesis	pathogenesis	NOUN
bptjm-16	79	22	of	of	ADP
bptjm-16	79	23	autoimmune	autoimmune	ADJ
bptjm-16	79	24	diseases	disease	NOUN
bptjm-16	79	25	.	.	PUNCT
bptjm-16	80	1	necrosis	necrosis	NOUN
bptjm-16	80	2	necrosis	necrosis	NOUN
bptjm-16	80	3	is	be	AUX
bptjm-16	80	4	an	an	DET
bptjm-16	80	5	unregulated	unregulated	ADJ
bptjm-16	80	6	or	or	CCONJ
bptjm-16	80	7	accidental	accidental	ADJ
bptjm-16	80	8	cell	cell	NOUN
bptjm-16	80	9	death	death	NOUN
bptjm-16	80	10	due	due	ADP
bptjm-16	80	11	to	to	ADP
bptjm-16	80	12	internal	internal	ADJ
bptjm-16	80	13	or	or	CCONJ
bptjm-16	80	14	external	external	ADJ
bptjm-16	80	15	stresses	stress	NOUN
bptjm-16	80	16	,	,	PUNCT
bptjm-16	80	17	resulting	result	VERB
bptjm-16	80	18	from	from	ADP
bptjm-16	80	19	the	the	DET
bptjm-16	80	20	disruption	disruption	NOUN
bptjm-16	80	21	of	of	ADP
bptjm-16	80	22	membrane	membrane	NOUN
bptjm-16	80	23	homeostasis	homeostasis	NOUN
bptjm-16	80	24	it	it	PRON
bptjm-16	80	25	leads	lead	VERB
bptjm-16	80	26	to	to	ADP
bptjm-16	80	27	water	water	NOUN
bptjm-16	80	28	imbalance	imbalance	NOUN
bptjm-16	80	29	between	between	ADP
bptjm-16	80	30	the	the	DET
bptjm-16	80	31	extracellular	extracellular	ADJ
bptjm-16	80	32	and	and	CCONJ
bptjm-16	80	33	intracellular	intracellular	ADJ
bptjm-16	80	34	environments50,51,52	environments50,51,52	VERB
bptjm-16	80	35	.	.	PUNCT
bptjm-16	81	1	recently	recently	ADV
bptjm-16	81	2	it	it	PRON
bptjm-16	81	3	has	have	AUX
bptjm-16	81	4	been	be	AUX
bptjm-16	81	5	suggested	suggest	VERB
bptjm-16	81	6	that	that	SCONJ
bptjm-16	81	7	a	a	DET
bptjm-16	81	8	programmed	program	VERB
bptjm-16	81	9	berkeley	berkeley	PROPN
bptjm-16	81	10	pharma	pharma	PROPN
bptjm-16	81	11	tech	tech	NOUN
bptjm-16	81	12	journal	journal	NOUN
bptjm-16	81	13	of	of	ADP
bptjm-16	81	14	medicine	medicine	NOUN
bptjm-16	81	15	|	|	ADV
bptjm-16	81	16	101	101	NUM
bptjm-16	81	17	form	form	NOUN
bptjm-16	81	18	of	of	ADP
bptjm-16	81	19	necrosis	necrosis	NOUN
bptjm-16	81	20	,	,	PUNCT
bptjm-16	81	21	commonly	commonly	ADV
bptjm-16	81	22	known	know	VERB
bptjm-16	81	23	as	as	ADP
bptjm-16	81	24	necroptosis	necroptosis	NOUN
bptjm-16	81	25	,	,	PUNCT
bptjm-16	81	26	is	be	AUX
bptjm-16	81	27	a	a	DET
bptjm-16	81	28	critical	critical	ADJ
bptjm-16	81	29	pathway	pathway	NOUN
bptjm-16	81	30	that	that	PRON
bptjm-16	81	31	is	be	AUX
bptjm-16	81	32	involved	involve	VERB
bptjm-16	81	33	in	in	ADP
bptjm-16	81	34	a	a	DET
bptjm-16	81	35	number	number	NOUN
bptjm-16	81	36	of	of	ADP
bptjm-16	81	37	autoimmune	autoimmune	ADJ
bptjm-16	81	38	diseases	disease	NOUN
bptjm-16	81	39	,	,	PUNCT
bptjm-16	81	40	as	as	ADV
bptjm-16	81	41	well	well	ADV
bptjm-16	81	42	as	as	ADP
bptjm-16	81	43	heart	heart	NOUN
bptjm-16	81	44	diseases	disease	NOUN
bptjm-16	81	45	.	.	PUNCT
bptjm-16	82	1	the	the	DET
bptjm-16	82	2	discovery	discovery	NOUN
bptjm-16	82	3	of	of	ADP
bptjm-16	82	4	necroptosis	necroptosis	NOUN
bptjm-16	82	5	signi	signi	ADJ
bptjm-16	82	6	es	es	ADP
bptjm-16	82	7	the	the	DET
bptjm-16	82	8	need	need	NOUN
bptjm-16	82	9	to	to	PART
bptjm-16	82	10	di	di	VERB
bptjm-16	82	11	erentiate	erentiate	NOUN
bptjm-16	82	12	between	between	ADP
bptjm-16	82	13	the	the	DET
bptjm-16	82	14	mechanisms	mechanism	NOUN
bptjm-16	82	15	that	that	PRON
bptjm-16	82	16	induce	induce	VERB
bptjm-16	82	17	passive	passive	ADJ
bptjm-16	82	18	necrosis	necrosis	NOUN
bptjm-16	82	19	,	,	PUNCT
bptjm-16	82	20	and	and	CCONJ
bptjm-16	82	21	those	those	PRON
bptjm-16	82	22	that	that	PRON
bptjm-16	82	23	stimulate	stimulate	VERB
bptjm-16	82	24	necroptosis	necroptosis	NOUN
bptjm-16	82	25	,	,	PUNCT
bptjm-16	82	26	to	to	PART
bptjm-16	82	27	better	well	ADV
bptjm-16	82	28	understand	understand	VERB
bptjm-16	82	29	disease	disease	NOUN
bptjm-16	82	30	progression8,9	progression8,9	PROPN
bptjm-16	82	31	.	.	PUNCT
bptjm-16	83	1	although	although	SCONJ
bptjm-16	83	2	necrosis	necrosis	NOUN
bptjm-16	83	3	and	and	CCONJ
bptjm-16	83	4	necroptosis	necroptosis	NOUN
bptjm-16	83	5	share	share	NOUN
bptjm-16	83	6	nearly	nearly	ADV
bptjm-16	83	7	identical	identical	ADJ
bptjm-16	83	8	characteristics	characteristic	NOUN
bptjm-16	83	9	,	,	PUNCT
bptjm-16	83	10	the	the	DET
bptjm-16	83	11	implication	implication	NOUN
bptjm-16	83	12	of	of	ADP
bptjm-16	83	13	necroptosis	necroptosis	NOUN
bptjm-16	83	14	in	in	ADP
bptjm-16	83	15	several	several	ADJ
bptjm-16	83	16	diseases	disease	NOUN
bptjm-16	83	17	raises	raise	VERB
bptjm-16	83	18	a	a	DET
bptjm-16	83	19	topic	topic	NOUN
bptjm-16	83	20	of	of	ADP
bptjm-16	83	21	interest	interest	NOUN
bptjm-16	83	22	in	in	ADP
bptjm-16	83	23	research	research	NOUN
bptjm-16	83	24	studying	study	VERB
bptjm-16	83	25	autoimmune	autoimmune	ADJ
bptjm-16	83	26	diseases	disease	NOUN
bptjm-16	83	27	.	.	PUNCT
bptjm-16	84	1	although	although	SCONJ
bptjm-16	84	2	there	there	PRON
bptjm-16	84	3	are	be	VERB
bptjm-16	84	4	some	some	DET
bptjm-16	84	5	morphological	morphological	ADJ
bptjm-16	84	6	and	and	CCONJ
bptjm-16	84	7	mechanistic	mechanistic	ADJ
bptjm-16	84	8	di	di	NOUN
bptjm-16	84	9	erences	erence	NOUN
bptjm-16	84	10	between	between	ADP
bptjm-16	84	11	apoptosis	apoptosis	NOUN
bptjm-16	84	12	and	and	CCONJ
bptjm-16	84	13	necrosis	necrosis	NOUN
bptjm-16	84	14	,	,	PUNCT
bptjm-16	84	15	these	these	DET
bptjm-16	84	16	two	two	NUM
bptjm-16	84	17	processes	process	NOUN
bptjm-16	84	18	overlap	overlap	NOUN
bptjm-16	84	19	in	in	ADP
bptjm-16	84	20	some	some	DET
bptjm-16	84	21	ways	way	NOUN
bptjm-16	84	22	.	.	PUNCT
bptjm-16	85	1	evidence	evidence	NOUN
bptjm-16	85	2	indicates	indicate	VERB
bptjm-16	85	3	that	that	SCONJ
bptjm-16	85	4	necrosis	necrosis	NOUN
bptjm-16	85	5	and	and	CCONJ
bptjm-16	85	6	apoptosis	apoptosis	NOUN
bptjm-16	85	7	share	share	NOUN
bptjm-16	85	8	a	a	DET
bptjm-16	85	9	biochemical	biochemical	ADJ
bptjm-16	85	10	network	network	NOUN
bptjm-16	85	11	described	describe	VERB
bptjm-16	85	12	as	as	ADP
bptjm-16	85	13	the	the	DET
bptjm-16	85	14	“	"	PUNCT
bptjm-16	85	15	apoptosis	apoptosis	NOUN
bptjm-16	85	16	-	-	PUNCT
bptjm-16	85	17	necrosis	necrosis	NOUN
bptjm-16	85	18	continuum	continuum	NOUN
bptjm-16	85	19	.	.	PUNCT
bptjm-16	86	1	”53	”53	ADJ
bptjm-16	86	2	for	for	ADP
bptjm-16	86	3	example	example	NOUN
bptjm-16	86	4	,	,	PUNCT
bptjm-16	86	5	a	a	DET
bptjm-16	86	6	decrease	decrease	NOUN
bptjm-16	86	7	in	in	ADP
bptjm-16	86	8	the	the	DET
bptjm-16	86	9	availability	availability	NOUN
bptjm-16	86	10	of	of	ADP
bptjm-16	86	11	caspases	caspase	NOUN
bptjm-16	86	12	,	,	PUNCT
bptjm-16	86	13	or	or	CCONJ
bptjm-16	86	14	intracellular	intracellular	ADJ
bptjm-16	86	15	atp	atp	NOUN
bptjm-16	86	16	,	,	PUNCT
bptjm-16	86	17	can	can	AUX
bptjm-16	86	18	convert	convert	VERB
bptjm-16	86	19	an	an	DET
bptjm-16	86	20	ongoing	ongoing	ADJ
bptjm-16	86	21	apoptotic	apoptotic	ADJ
bptjm-16	86	22	process	process	NOUN
bptjm-16	86	23	into	into	ADP
bptjm-16	86	24	a	a	DET
bptjm-16	86	25	necrotic	necrotic	ADJ
bptjm-16	86	26	process54,55	process54,55	NOUN
bptjm-16	86	27	.	.	PUNCT
bptjm-16	87	1	the	the	DET
bptjm-16	87	2	tissue	tissue	NOUN
bptjm-16	87	3	type	type	NOUN
bptjm-16	87	4	,	,	PUNCT
bptjm-16	87	5	the	the	DET
bptjm-16	87	6	nature	nature	NOUN
bptjm-16	87	7	of	of	ADP
bptjm-16	87	8	the	the	DET
bptjm-16	87	9	cell	cell	NOUN
bptjm-16	87	10	death	death	NOUN
bptjm-16	87	11	signal	signal	NOUN
bptjm-16	87	12	,	,	PUNCT
bptjm-16	87	13	the	the	DET
bptjm-16	87	14	physiological	physiological	NOUN
bptjm-16	87	15	make	make	VERB
bptjm-16	87	16	up	up	ADP
bptjm-16	87	17	,	,	PUNCT
bptjm-16	87	18	and	and	CCONJ
bptjm-16	87	19	the	the	DET
bptjm-16	87	20	developmental	developmental	ADJ
bptjm-16	87	21	stage	stage	NOUN
bptjm-16	87	22	of	of	ADP
bptjm-16	87	23	the	the	DET
bptjm-16	87	24	tissue	tissue	NOUN
bptjm-16	87	25	all	all	PRON
bptjm-16	87	26	determine	determine	VERB
bptjm-16	87	27	whether	whether	SCONJ
bptjm-16	87	28	a	a	DET
bptjm-16	87	29	cell	cell	NOUN
bptjm-16	87	30	dies	die	VERB
bptjm-16	87	31	by	by	ADP
bptjm-16	87	32	necrosis	necrosis	NOUN
bptjm-16	87	33	,	,	PUNCT
bptjm-16	87	34	or	or	CCONJ
bptjm-16	87	35	apoptosis53,56	apoptosis53,56	NOUN
bptjm-16	87	36	.	.	PUNCT
bptjm-16	88	1	using	use	VERB
bptjm-16	88	2	conventional	conventional	ADJ
bptjm-16	88	3	histology	histology	NOUN
bptjm-16	88	4	to	to	PART
bptjm-16	88	5	distinguish	distinguish	VERB
bptjm-16	88	6	between	between	ADP
bptjm-16	88	7	apoptosis	apoptosis	NOUN
bptjm-16	88	8	and	and	CCONJ
bptjm-16	88	9	necrosis	necrosis	NOUN
bptjm-16	88	10	proves	prove	VERB
bptjm-16	88	11	di	di	NOUN
bptjm-16	88	12	cult	cult	NOUN
bptjm-16	88	13	,	,	PUNCT
bptjm-16	88	14	as	as	SCONJ
bptjm-16	88	15	they	they	PRON
bptjm-16	88	16	can	can	AUX
bptjm-16	88	17	occur	occur	AUX
bptjm-16	88	18	simultaneously	simultaneously	ADV
bptjm-16	88	19	depending	depend	VERB
bptjm-16	88	20	on	on	ADP
bptjm-16	88	21	factors	factor	NOUN
bptjm-16	88	22	such	such	ADJ
bptjm-16	88	23	as	as	ADP
bptjm-16	88	24	the	the	DET
bptjm-16	88	25	availability	availability	NOUN
bptjm-16	88	26	of	of	ADP
bptjm-16	88	27	caspases	caspase	NOUN
bptjm-16	88	28	,	,	PUNCT
bptjm-16	88	29	the	the	DET
bptjm-16	88	30	intensity	intensity	NOUN
bptjm-16	88	31	and	and	CCONJ
bptjm-16	88	32	duration	duration	NOUN
bptjm-16	88	33	of	of	ADP
bptjm-16	88	34	the	the	DET
bptjm-16	88	35	stimulus	stimulus	NOUN
bptjm-16	88	36	,	,	PUNCT
bptjm-16	88	37	and	and	CCONJ
bptjm-16	88	38	the	the	DET
bptjm-16	88	39	extent	extent	NOUN
bptjm-16	88	40	of	of	ADP
bptjm-16	88	41	atp	atp	PROPN
bptjm-16	88	42	depletion53	depletion53	PROPN
bptjm-16	88	43	.	.	PUNCT
bptjm-16	89	1	one	one	NUM
bptjm-16	89	2	of	of	ADP
bptjm-16	89	3	the	the	DET
bptjm-16	89	4	primary	primary	ADJ
bptjm-16	89	5	di	di	NOUN
bptjm-16	89	6	erences	erence	NOUN
bptjm-16	89	7	is	be	AUX
bptjm-16	89	8	that	that	SCONJ
bptjm-16	89	9	necrosis	necrosis	NOUN
bptjm-16	89	10	is	be	AUX
bptjm-16	89	11	an	an	DET
bptjm-16	89	12	unregulated	unregulated	ADJ
bptjm-16	89	13	,	,	PUNCT
bptjm-16	89	14	passive	passive	ADJ
bptjm-16	89	15	process	process	NOUN
bptjm-16	89	16	that	that	PRON
bptjm-16	89	17	usually	usually	ADV
bptjm-16	89	18	impacts	impact	VERB
bptjm-16	89	19	a	a	DET
bptjm-16	89	20	large	large	ADJ
bptjm-16	89	21	range	range	NOUN
bptjm-16	89	22	of	of	ADP
bptjm-16	89	23	cells	cell	NOUN
bptjm-16	89	24	.	.	PUNCT
bptjm-16	90	1	apoptosis	apoptosis	NOUN
bptjm-16	90	2	is	be	AUX
bptjm-16	90	3	contained	contain	VERB
bptjm-16	90	4	,	,	PUNCT
bptjm-16	90	5	energy	energy	NOUN
bptjm-16	90	6	-	-	PUNCT
bptjm-16	90	7	dependent	dependent	ADJ
bptjm-16	90	8	,	,	PUNCT
bptjm-16	90	9	and	and	CCONJ
bptjm-16	90	10	can	can	AUX
bptjm-16	90	11	a	a	DET
bptjm-16	90	12	ect	ect	ADJ
bptjm-16	90	13	clusters	cluster	NOUN
bptjm-16	90	14	or	or	CCONJ
bptjm-16	90	15	individual	individual	ADJ
bptjm-16	90	16	cells	cell	NOUN
bptjm-16	90	17	.	.	PUNCT
bptjm-16	91	1	necrosis	necrosis	NOUN
bptjm-16	91	2	is	be	AUX
bptjm-16	91	3	initiated	initiate	VERB
bptjm-16	91	4	by	by	ADP
bptjm-16	91	5	two	two	NUM
bptjm-16	91	6	main	main	ADJ
bptjm-16	91	7	mechanisms	mechanism	NOUN
bptjm-16	91	8	:	:	PUNCT
bptjm-16	91	9	interference	interference	NOUN
bptjm-16	91	10	with	with	ADP
bptjm-16	91	11	the	the	DET
bptjm-16	91	12	energy	energy	NOUN
bptjm-16	91	13	supply	supply	NOUN
bptjm-16	91	14	of	of	ADP
bptjm-16	91	15	the	the	DET
bptjm-16	91	16	cell	cell	NOUN
bptjm-16	91	17	and	and	CCONJ
bptjm-16	91	18	direct	direct	ADJ
bptjm-16	91	19	damage	damage	NOUN
bptjm-16	91	20	to	to	ADP
bptjm-16	91	21	cell	cell	NOUN
bptjm-16	91	22	membranes	membrane	NOUN
bptjm-16	91	23	.	.	PUNCT
bptjm-16	92	1	on	on	ADP
bptjm-16	92	2	the	the	DET
bptjm-16	92	3	other	other	ADJ
bptjm-16	92	4	hand	hand	NOUN
bptjm-16	92	5	,	,	PUNCT
bptjm-16	92	6	there	there	PRON
bptjm-16	92	7	is	be	VERB
bptjm-16	92	8	virtually	virtually	ADV
bptjm-16	92	9	no	no	PRON
bptjm-16	92	10	in	in	ADP
bptjm-16	92	11	ammatory	ammatory	ADJ
bptjm-16	92	12	reaction	reaction	NOUN
bptjm-16	92	13	in	in	ADP
bptjm-16	92	14	apoptotic	apoptotic	ADJ
bptjm-16	92	15	cells	cell	NOUN
bptjm-16	92	16	,	,	PUNCT
bptjm-16	92	17	because	because	SCONJ
bptjm-16	92	18	they	they	PRON
bptjm-16	92	19	do	do	AUX
bptjm-16	92	20	not	not	PART
bptjm-16	92	21	release	release	VERB
bptjm-16	92	22	their	their	PRON
bptjm-16	92	23	cellular	cellular	ADJ
bptjm-16	92	24	constituents	constituent	NOUN
bptjm-16	92	25	into	into	ADP
bptjm-16	92	26	the	the	DET
bptjm-16	92	27	surrounding	surround	VERB
bptjm-16	92	28	interstitial	interstitial	ADJ
bptjm-16	92	29	tissue	tissue	NOUN
bptjm-16	92	30	and	and	CCONJ
bptjm-16	92	31	are	be	AUX
bptjm-16	92	32	quickly	quickly	ADV
bptjm-16	92	33	phagocytosed	phagocytose	VERB
bptjm-16	92	34	by	by	ADP
bptjm-16	92	35	macrophages	macrophage	NOUN
bptjm-16	92	36	or	or	CCONJ
bptjm-16	92	37	adjacent	adjacent	ADJ
bptjm-16	92	38	normal	normal	ADJ
bptjm-16	92	39	cells57,58	cells57,58	NOUN
bptjm-16	92	40	.	.	PUNCT
bptjm-16	93	1	necroptosis	necroptosis	NOUN
bptjm-16	93	2	necroptosis	necroptosis	NOUN
bptjm-16	93	3	di	di	NOUN
bptjm-16	93	4	ers	er	NOUN
bptjm-16	93	5	from	from	ADP
bptjm-16	93	6	apoptosis	apoptosis	NOUN
bptjm-16	93	7	in	in	ADP
bptjm-16	93	8	several	several	ADJ
bptjm-16	93	9	ways	way	NOUN
bptjm-16	93	10	.	.	PUNCT
bptjm-16	94	1	cellls	celll	NOUN
bptjm-16	94	2	undergoing	undergo	VERB
bptjm-16	94	3	apoptosis	apoptosis	NOUN
bptjm-16	94	4	maintain	maintain	VERB
bptjm-16	94	5	the	the	DET
bptjm-16	94	6	integrity	integrity	NOUN
bptjm-16	94	7	of	of	ADP
bptjm-16	94	8	their	their	PRON
bptjm-16	94	9	cell	cell	NOUN
bptjm-16	94	10	membrane	membrane	NOUN
bptjm-16	94	11	,	,	PUNCT
bptjm-16	94	12	whereas	whereas	SCONJ
bptjm-16	94	13	necroptosis	necroptosis	NOUN
bptjm-16	94	14	disrupts	disrupt	VERB
bptjm-16	94	15	the	the	DET
bptjm-16	94	16	cell	cell	NOUN
bptjm-16	94	17	membrane	membrane	NOUN
bptjm-16	94	18	.	.	PUNCT
bptjm-16	95	1	although	although	SCONJ
bptjm-16	95	2	apoptosis	apoptosis	NOUN
bptjm-16	95	3	and	and	CCONJ
bptjm-16	95	4	necroptosis	necroptosis	NOUN
bptjm-16	95	5	share	share	VERB
bptjm-16	95	6	certain	certain	ADJ
bptjm-16	95	7	triggers	trigger	NOUN
bptjm-16	95	8	,	,	PUNCT
bptjm-16	95	9	the	the	DET
bptjm-16	95	10	intracellular	intracellular	NOUN
bptjm-16	95	11	signaling	signal	VERB
bptjm-16	95	12	pathways	pathway	NOUN
bptjm-16	95	13	that	that	PRON
bptjm-16	95	14	ultimately	ultimately	ADV
bptjm-16	95	15	lead	lead	VERB
bptjm-16	95	16	to	to	ADP
bptjm-16	95	17	each	each	DET
bptjm-16	95	18	cascade	cascade	NOUN
bptjm-16	95	19	di	di	X
bptjm-16	95	20	er16	er16	PROPN
bptjm-16	95	21	.	.	PUNCT
bptjm-16	96	1	apoptosis	apoptosis	NOUN
bptjm-16	96	2	is	be	AUX
bptjm-16	96	3	known	know	VERB
bptjm-16	96	4	to	to	PART
bptjm-16	96	5	be	be	AUX
bptjm-16	96	6	regulated	regulate	VERB
bptjm-16	96	7	by	by	ADP
bptjm-16	96	8	key	key	ADJ
bptjm-16	96	9	mediators	mediator	NOUN
bptjm-16	96	10	called	call	VERB
bptjm-16	96	11	caspases	caspase	NOUN
bptjm-16	96	12	,	,	PUNCT
bptjm-16	96	13	whereas	whereas	SCONJ
bptjm-16	96	14	the	the	DET
bptjm-16	96	15	main	main	ADJ
bptjm-16	96	16	mediators	mediator	NOUN
bptjm-16	96	17	of	of	ADP
bptjm-16	96	18	berkeley	berkeley	PROPN
bptjm-16	96	19	pharma	pharma	PROPN
bptjm-16	96	20	tech	tech	NOUN
bptjm-16	96	21	journal	journal	NOUN
bptjm-16	96	22	of	of	ADP
bptjm-16	96	23	medicine	medicine	NOUN
bptjm-16	96	24	|	|	ADV
bptjm-16	96	25	102	102	NUM
bptjm-16	96	26	necroptosis	necroptosis	NOUN
bptjm-16	96	27	are	be	AUX
bptjm-16	96	28	receptor	receptor	NOUN
bptjm-16	96	29	-	-	PUNCT
bptjm-16	96	30	interacting	interact	VERB
bptjm-16	96	31	protein	protein	NOUN
bptjm-16	96	32	kinases	kinase	NOUN
bptjm-16	96	33	(	(	PUNCT
bptjm-16	96	34	ripks	ripks	NOUN
bptjm-16	96	35	)	)	PUNCT
bptjm-16	96	36	.	.	PUNCT
bptjm-16	97	1	additionally	additionally	ADV
bptjm-16	97	2	,	,	PUNCT
bptjm-16	97	3	apoptosis	apoptosis	NOUN
bptjm-16	97	4	and	and	CCONJ
bptjm-16	97	5	necroptosis	necroptosis	NOUN
bptjm-16	97	6	intersect	intersect	NOUN
bptjm-16	97	7	at	at	ADP
bptjm-16	97	8	several	several	ADJ
bptjm-16	97	9	points	point	NOUN
bptjm-16	97	10	during	during	ADP
bptjm-16	97	11	the	the	DET
bptjm-16	97	12	signal	signal	ADJ
bptjm-16	97	13	transduction	transduction	NOUN
bptjm-16	97	14	process	process	NOUN
bptjm-16	97	15	.	.	PUNCT
bptjm-16	98	1	one	one	NUM
bptjm-16	98	2	of	of	ADP
bptjm-16	98	3	the	the	DET
bptjm-16	98	4	most	most	ADV
bptjm-16	98	5	well	well	ADV
bptjm-16	98	6	-	-	PUNCT
bptjm-16	98	7	researched	research	VERB
bptjm-16	98	8	convergence	convergence	NOUN
bptjm-16	98	9	points	point	NOUN
bptjm-16	98	10	between	between	ADP
bptjm-16	98	11	the	the	DET
bptjm-16	98	12	two	two	NUM
bptjm-16	98	13	processes	process	NOUN
bptjm-16	98	14	is	be	AUX
bptjm-16	98	15	the	the	DET
bptjm-16	98	16	role	role	NOUN
bptjm-16	98	17	of	of	ADP
bptjm-16	98	18	caspase-8	caspase-8	NOUN
bptjm-16	98	19	in	in	ADP
bptjm-16	98	20	inhibiting	inhibit	VERB
bptjm-16	98	21	necroptosis	necroptosis	NOUN
bptjm-16	98	22	by	by	ADP
bptjm-16	98	23	cleaving	cleave	VERB
bptjm-16	98	24	necroptosis	necroptosis	NOUN
bptjm-16	98	25	mediators59,60	mediators59,60	NOUN
bptjm-16	98	26	.	.	PUNCT
bptjm-16	99	1	in	in	ADP
bptjm-16	99	2	simple	simple	ADJ
bptjm-16	99	3	terms	term	NOUN
bptjm-16	99	4	,	,	PUNCT
bptjm-16	99	5	necroptosis	necroptosis	NOUN
bptjm-16	99	6	is	be	AUX
bptjm-16	99	7	a	a	DET
bptjm-16	99	8	cellular	cellular	ADJ
bptjm-16	99	9	response	response	NOUN
bptjm-16	99	10	to	to	ADP
bptjm-16	99	11	environmental	environmental	ADJ
bptjm-16	99	12	stress	stress	NOUN
bptjm-16	99	13	,	,	PUNCT
bptjm-16	99	14	triggered	trigger	VERB
bptjm-16	99	15	by	by	ADP
bptjm-16	99	16	mechanical	mechanical	ADJ
bptjm-16	99	17	or	or	CCONJ
bptjm-16	99	18	chemical	chemical	NOUN
bptjm-16	99	19	injury	injury	NOUN
bptjm-16	99	20	,	,	PUNCT
bptjm-16	99	21	in	in	ADP
bptjm-16	99	22	ammation	ammation	NOUN
bptjm-16	99	23	,	,	PUNCT
bptjm-16	99	24	or	or	CCONJ
bptjm-16	99	25	infection	infection	NOUN
bptjm-16	99	26	.	.	PUNCT
bptjm-16	100	1	the	the	DET
bptjm-16	100	2	existing	exist	VERB
bptjm-16	100	3	knowledge	knowledge	NOUN
bptjm-16	100	4	of	of	ADP
bptjm-16	100	5	necroptosis	necroptosis	NOUN
bptjm-16	100	6	revolves	revolve	VERB
bptjm-16	100	7	around	around	ADP
bptjm-16	100	8	a	a	DET
bptjm-16	100	9	key	key	ADJ
bptjm-16	100	10	signaling	signal	VERB
bptjm-16	100	11	molecular	molecular	ADJ
bptjm-16	100	12	pathway	pathway	NOUN
bptjm-16	100	13	:	:	PUNCT
bptjm-16	100	14	the	the	DET
bptjm-16	100	15	tnf	tnf	PROPN
bptjm-16	100	16	-	-	PUNCT
bptjm-16	100	17	α	α	PROPN
bptjm-16	100	18	receptor	receptor	NOUN
bptjm-16	100	19	system	system	NOUN
bptjm-16	100	20	—	—	PUNCT
bptjm-16	100	21	a	a	DET
bptjm-16	100	22	pleiotropic	pleiotropic	ADJ
bptjm-16	100	23	molecule	molecule	NOUN
bptjm-16	100	24	capable	capable	ADJ
bptjm-16	100	25	of	of	ADP
bptjm-16	100	26	inducing	induce	VERB
bptjm-16	100	27	a	a	DET
bptjm-16	100	28	survival	survival	NOUN
bptjm-16	100	29	,	,	PUNCT
bptjm-16	100	30	apoptotic	apoptotic	ADJ
bptjm-16	100	31	,	,	PUNCT
bptjm-16	100	32	or	or	CCONJ
bptjm-16	100	33	necroptotic	necroptotic	ADJ
bptjm-16	100	34	response	response	NOUN
bptjm-16	100	35	based	base	VERB
bptjm-16	100	36	upon	upon	SCONJ
bptjm-16	100	37	the	the	DET
bptjm-16	100	38	assembly	assembly	NOUN
bptjm-16	100	39	of	of	ADP
bptjm-16	100	40	various	various	ADJ
bptjm-16	100	41	sequential	sequential	ADJ
bptjm-16	100	42	cell	cell	NOUN
bptjm-16	100	43	death	death	NOUN
bptjm-16	100	44	complexes61,62	complexes61,62	NOUN
bptjm-16	100	45	.	.	PUNCT
bptjm-16	101	1	under	under	ADP
bptjm-16	101	2	some	some	DET
bptjm-16	101	3	cellular	cellular	ADJ
bptjm-16	101	4	conditions	condition	NOUN
bptjm-16	101	5	,	,	PUNCT
bptjm-16	101	6	the	the	DET
bptjm-16	101	7	binding	binding	NOUN
bptjm-16	101	8	of	of	ADP
bptjm-16	101	9	the	the	DET
bptjm-16	101	10	ligand	ligand	NOUN
bptjm-16	101	11	tnf	tnf	PROPN
bptjm-16	101	12	-	-	PUNCT
bptjm-16	101	13	α	α	NOUN
bptjm-16	101	14	to	to	ADP
bptjm-16	101	15	the	the	DET
bptjm-16	101	16	receptor	receptor	NOUN
bptjm-16	101	17	tnf	tnf	PROPN
bptjm-16	101	18	-	-	PUNCT
bptjm-16	101	19	ri	ri	PROPN
bptjm-16	101	20	triggers	trigger	VERB
bptjm-16	101	21	the	the	DET
bptjm-16	101	22	formation	formation	NOUN
bptjm-16	101	23	of	of	ADP
bptjm-16	101	24	complex	complex	ADJ
bptjm-16	101	25	i	i	PRON
bptjm-16	101	26	(	(	PUNCT
bptjm-16	101	27	a	a	DET
bptjm-16	101	28	prosurvival	prosurvival	NOUN
bptjm-16	101	29	complex	complex	NOUN
bptjm-16	101	30	that	that	PRON
bptjm-16	101	31	signals	signal	VERB
bptjm-16	101	32	through	through	ADP
bptjm-16	101	33	nf	nf	NOUN
bptjm-16	101	34	-	-	PUNCT
bptjm-16	101	35	κb	κb	NOUN
bptjm-16	101	36	)	)	PUNCT
bptjm-16	101	37	.	.	PUNCT
bptjm-16	102	1	however	however	ADV
bptjm-16	102	2	,	,	PUNCT
bptjm-16	102	3	in	in	ADP
bptjm-16	102	4	cases	case	NOUN
bptjm-16	102	5	where	where	SCONJ
bptjm-16	102	6	ripk1	ripk1	NOUN
bptjm-16	102	7	is	be	AUX
bptjm-16	102	8	de	de	X
bptjm-16	102	9	ubiquitinated	ubiquitinated	ADJ
bptjm-16	102	10	,	,	PUNCT
bptjm-16	102	11	the	the	DET
bptjm-16	102	12	complex	complex	NOUN
bptjm-16	102	13	has	have	AUX
bptjm-16	102	14	become	become	VERB
bptjm-16	102	15	an	an	DET
bptjm-16	102	16	apoptotic	apoptotic	ADJ
bptjm-16	102	17	complex	complex	ADJ
bptjm-16	102	18	iia63	iia63	NOUN
bptjm-16	102	19	.	.	PUNCT
bptjm-16	103	1	furthermore	furthermore	ADV
bptjm-16	103	2	,	,	PUNCT
bptjm-16	103	3	the	the	DET
bptjm-16	103	4	absence	absence	NOUN
bptjm-16	103	5	of	of	ADP
bptjm-16	103	6	caspase	caspase	PROPN
bptjm-16	103	7	8	8	NUM
bptjm-16	103	8	,	,	PUNCT
bptjm-16	103	9	in	in	ADP
bptjm-16	103	10	addition	addition	NOUN
bptjm-16	103	11	to	to	ADP
bptjm-16	103	12	elevated	elevated	ADJ
bptjm-16	103	13	levels	level	NOUN
bptjm-16	103	14	of	of	ADP
bptjm-16	103	15	receptor	receptor	NOUN
bptjm-16	103	16	-	-	PUNCT
bptjm-16	103	17	interacting	interact	VERB
bptjm-16	103	18	serine	serine	NOUN
bptjm-16	103	19	/	/	SYM
bptjm-16	103	20	threonine	threonine	ADJ
bptjm-16	103	21	-	-	PUNCT
bptjm-16	103	22	protein	protein	NOUN
bptjm-16	103	23	kinase	kinase	NOUN
bptjm-16	103	24	3	3	NUM
bptjm-16	103	25	(	(	PUNCT
bptjm-16	103	26	ripk3	ripk3	NOUN
bptjm-16	103	27	)	)	PUNCT
bptjm-16	103	28	,	,	PUNCT
bptjm-16	103	29	alter	alter	VERB
bptjm-16	103	30	the	the	DET
bptjm-16	103	31	complex	complex	NOUN
bptjm-16	103	32	to	to	ADP
bptjm-16	103	33	iib	iib	PROPN
bptjm-16	103	34	(	(	PUNCT
bptjm-16	103	35	also	also	ADV
bptjm-16	103	36	called	call	VERB
bptjm-16	103	37	the	the	DET
bptjm-16	103	38	necrosome	necrosome	NOUN
bptjm-16	103	39	)	)	PUNCT
bptjm-16	103	40	.	.	PUNCT
bptjm-16	104	1	this	this	DET
bptjm-16	104	2	necrosome	necrosome	NOUN
bptjm-16	104	3	contains	contain	VERB
bptjm-16	104	4	ripk1	ripk1	NOUN
bptjm-16	104	5	,	,	PUNCT
bptjm-16	104	6	ripk3	ripk3	NOUN
bptjm-16	104	7	and	and	CCONJ
bptjm-16	104	8	the	the	DET
bptjm-16	104	9	fas	fas	ADJ
bptjm-16	104	10	-	-	PUNCT
bptjm-16	104	11	associated	associate	VERB
bptjm-16	104	12	protein	protein	NOUN
bptjm-16	104	13	with	with	ADP
bptjm-16	104	14	death	death	NOUN
bptjm-16	104	15	domain	domain	NOUN
bptjm-16	104	16	,	,	PUNCT
bptjm-16	104	17	allowing	allow	VERB
bptjm-16	104	18	the	the	DET
bptjm-16	104	19	cell	cell	NOUN
bptjm-16	104	20	to	to	PART
bptjm-16	104	21	undergo	undergo	VERB
bptjm-16	104	22	necroptosis	necroptosis	NOUN
bptjm-16	104	23	via	via	ADP
bptjm-16	104	24	direct	direct	ADJ
bptjm-16	104	25	phosphorylation	phosphorylation	NOUN
bptjm-16	104	26	of	of	ADP
bptjm-16	104	27	mixed	mixed	ADJ
bptjm-16	104	28	lineage	lineage	NOUN
bptjm-16	104	29	kinase	kinase	NOUN
bptjm-16	104	30	domain	domain	NOUN
bptjm-16	104	31	-	-	PUNCT
bptjm-16	104	32	like	like	ADJ
bptjm-16	104	33	protein	protein	NOUN
bptjm-16	104	34	(	(	PUNCT
bptjm-16	104	35	mlkl	mlkl	PROPN
bptjm-16	104	36	)	)	PUNCT
bptjm-16	104	37	by	by	ADP
bptjm-16	104	38	ripk364,65	ripk364,65	PROPN
bptjm-16	104	39	.	.	PUNCT
bptjm-16	105	1	phosphorylation	phosphorylation	NOUN
bptjm-16	105	2	of	of	ADP
bptjm-16	105	3	mlkl	mlkl	PROPN
bptjm-16	105	4	results	result	NOUN
bptjm-16	105	5	in	in	ADP
bptjm-16	105	6	a	a	DET
bptjm-16	105	7	pore	pore	ADV
bptjm-16	105	8	-	-	PUNCT
bptjm-16	105	9	forming	form	VERB
bptjm-16	105	10	oligomer	oligomer	NOUN
bptjm-16	105	11	that	that	PRON
bptjm-16	105	12	punctures	puncture	VERB
bptjm-16	105	13	the	the	DET
bptjm-16	105	14	plasma	plasma	NOUN
bptjm-16	105	15	membrane	membrane	NOUN
bptjm-16	105	16	and	and	CCONJ
bptjm-16	105	17	causes	cause	VERB
bptjm-16	105	18	subsequent	subsequent	ADJ
bptjm-16	105	19	cell	cell	NOUN
bptjm-16	105	20	death66	death66	NOUN
bptjm-16	105	21	.	.	PUNCT
bptjm-16	106	1	figure	figure	VERB
bptjm-16	106	2	2	2	NUM
bptjm-16	106	3	:	:	PUNCT
bptjm-16	106	4	tnfr1	tnfr1	NOUN
bptjm-16	106	5	-	-	PUNCT
bptjm-16	106	6	mediated	mediate	VERB
bptjm-16	106	7	cell	cell	NOUN
bptjm-16	106	8	death	death	NOUN
bptjm-16	106	9	and	and	CCONJ
bptjm-16	106	10	survival	survival	PROPN
bptjm-16	106	11	pathways	pathways	PROPN
bptjm-16	106	12	berkeley	berkeley	PROPN
bptjm-16	106	13	pharma	pharma	PROPN
bptjm-16	106	14	tech	tech	NOUN
bptjm-16	106	15	journal	journal	NOUN
bptjm-16	106	16	of	of	ADP
bptjm-16	106	17	medicine	medicine	NOUN
bptjm-16	106	18	|	|	ADV
bptjm-16	106	19	103	103	NUM
bptjm-16	106	20	a	a	DET
bptjm-16	106	21	number	number	NOUN
bptjm-16	106	22	of	of	ADP
bptjm-16	106	23	proin	proin	NOUN
bptjm-16	106	24	ammatory	ammatory	NOUN
bptjm-16	106	25	cytokines	cytokine	NOUN
bptjm-16	106	26	,	,	PUNCT
bptjm-16	106	27	such	such	ADJ
bptjm-16	106	28	as	as	ADP
bptjm-16	106	29	the	the	DET
bptjm-16	106	30	key	key	ADJ
bptjm-16	106	31	mediators	mediator	NOUN
bptjm-16	106	32	of	of	ADP
bptjm-16	106	33	necroptosis	necroptosis	NOUN
bptjm-16	106	34	,	,	PUNCT
bptjm-16	106	35	tnf	tnf	PROPN
bptjm-16	106	36	-	-	PUNCT
bptjm-16	106	37	α	α	PROPN
bptjm-16	106	38	and	and	CCONJ
bptjm-16	106	39	il-1β	il-1β	PROPN
bptjm-16	106	40	,	,	PUNCT
bptjm-16	106	41	as	as	ADV
bptjm-16	106	42	well	well	ADV
bptjm-16	106	43	as	as	ADP
bptjm-16	106	44	in	in	ADP
bptjm-16	106	45	ammatory	ammatory	ADJ
bptjm-16	106	46	cells	cell	NOUN
bptjm-16	106	47	,	,	PUNCT
bptjm-16	106	48	can	can	AUX
bptjm-16	106	49	cause	cause	VERB
bptjm-16	106	50	cell	cell	NOUN
bptjm-16	106	51	death67	death67	NOUN
bptjm-16	106	52	.	.	PUNCT
bptjm-16	107	1	however	however	ADV
bptjm-16	107	2	,	,	PUNCT
bptjm-16	107	3	the	the	DET
bptjm-16	107	4	pathological	pathological	ADJ
bptjm-16	107	5	manifestation	manifestation	NOUN
bptjm-16	107	6	of	of	ADP
bptjm-16	107	7	in	in	ADP
bptjm-16	107	8	ammation	ammation	NOUN
bptjm-16	107	9	varies	vary	VERB
bptjm-16	107	10	according	accord	VERB
bptjm-16	107	11	to	to	ADP
bptjm-16	107	12	the	the	DET
bptjm-16	107	13	type	type	NOUN
bptjm-16	107	14	of	of	ADP
bptjm-16	107	15	cell	cell	NOUN
bptjm-16	107	16	death	death	NOUN
bptjm-16	107	17	.	.	PUNCT
bptjm-16	108	1	apoptosis	apoptosis	NOUN
bptjm-16	108	2	generates	generate	VERB
bptjm-16	108	3	a	a	DET
bptjm-16	108	4	milder	mild	ADJ
bptjm-16	108	5	in	in	ADP
bptjm-16	108	6	ammatory	ammatory	ADJ
bptjm-16	108	7	response	response	NOUN
bptjm-16	108	8	because	because	SCONJ
bptjm-16	108	9	it	it	PRON
bptjm-16	108	10	maintains	maintain	VERB
bptjm-16	108	11	the	the	DET
bptjm-16	108	12	integrity	integrity	NOUN
bptjm-16	108	13	of	of	ADP
bptjm-16	108	14	the	the	DET
bptjm-16	108	15	cell	cell	NOUN
bptjm-16	108	16	membrane	membrane	NOUN
bptjm-16	108	17	and	and	CCONJ
bptjm-16	108	18	avoids	avoid	VERB
bptjm-16	108	19	the	the	DET
bptjm-16	108	20	overspill	overspill	NOUN
bptjm-16	108	21	of	of	ADP
bptjm-16	108	22	intracellular	intracellular	ADJ
bptjm-16	108	23	contents68	contents68	NOUN
bptjm-16	108	24	.	.	PUNCT
bptjm-16	109	1	conversely	conversely	ADV
bptjm-16	109	2	,	,	PUNCT
bptjm-16	109	3	necroptosis	necroptosis	NOUN
bptjm-16	109	4	directly	directly	ADV
bptjm-16	109	5	activates	activate	VERB
bptjm-16	109	6	and	and	CCONJ
bptjm-16	109	7	regulates	regulate	VERB
bptjm-16	109	8	in	in	ADP
bptjm-16	109	9	ammatory	ammatory	NOUN
bptjm-16	109	10	responses	response	NOUN
bptjm-16	109	11	by	by	ADP
bptjm-16	109	12	releasing	release	VERB
bptjm-16	109	13	intracellular	intracellular	ADJ
bptjm-16	109	14	contents	content	NOUN
bptjm-16	109	15	through	through	ADP
bptjm-16	109	16	the	the	DET
bptjm-16	109	17	ruptured	ruptured	ADJ
bptjm-16	109	18	plasma	plasma	NOUN
bptjm-16	109	19	membrane	membrane	NOUN
bptjm-16	109	20	.	.	PUNCT
bptjm-16	110	1	the	the	DET
bptjm-16	110	2	strong	strong	ADJ
bptjm-16	110	3	connection	connection	NOUN
bptjm-16	110	4	found	find	VERB
bptjm-16	110	5	between	between	ADP
bptjm-16	110	6	necroptosis	necroptosis	NOUN
bptjm-16	110	7	and	and	CCONJ
bptjm-16	110	8	in	in	ADP
bptjm-16	110	9	ammation	ammation	NOUN
bptjm-16	110	10	has	have	AUX
bptjm-16	110	11	been	be	AUX
bptjm-16	110	12	thought	think	VERB
bptjm-16	110	13	to	to	PART
bptjm-16	110	14	be	be	AUX
bptjm-16	110	15	the	the	DET
bptjm-16	110	16	primary	primary	ADJ
bptjm-16	110	17	component	component	NOUN
bptjm-16	110	18	of	of	ADP
bptjm-16	110	19	the	the	DET
bptjm-16	110	20	pathogenesis	pathogenesis	NOUN
bptjm-16	110	21	of	of	ADP
bptjm-16	110	22	necroptosis	necroptosis	NOUN
bptjm-16	110	23	associated	associate	VERB
bptjm-16	110	24	diseases	disease	NOUN
bptjm-16	110	25	.	.	PUNCT
bptjm-16	111	1	moreover	moreover	ADV
bptjm-16	111	2	,	,	PUNCT
bptjm-16	111	3	ripk1	ripk1	NOUN
bptjm-16	111	4	and	and	CCONJ
bptjm-16	111	5	ripk3	ripk3	NOUN
bptjm-16	111	6	have	have	AUX
bptjm-16	111	7	been	be	AUX
bptjm-16	111	8	found	find	VERB
bptjm-16	111	9	to	to	PART
bptjm-16	111	10	incite	incite	VERB
bptjm-16	111	11	an	an	DET
bptjm-16	111	12	in	in	ADP
bptjm-16	111	13	ammatory	ammatory	ADJ
bptjm-16	111	14	response	response	NOUN
bptjm-16	111	15	regardless	regardless	ADV
bptjm-16	111	16	of	of	ADP
bptjm-16	111	17	cell	cell	NOUN
bptjm-16	111	18	death69,70	death69,70	PROPN
bptjm-16	111	19	.	.	PUNCT
bptjm-16	112	1	these	these	DET
bptjm-16	112	2	distinguishable	distinguishable	ADJ
bptjm-16	112	3	characteristics	characteristic	NOUN
bptjm-16	112	4	of	of	ADP
bptjm-16	112	5	necroptosis	necroptosis	NOUN
bptjm-16	112	6	draw	draw	VERB
bptjm-16	112	7	interest	interest	NOUN
bptjm-16	112	8	to	to	ADP
bptjm-16	112	9	their	their	PRON
bptjm-16	112	10	implication	implication	NOUN
bptjm-16	112	11	in	in	ADP
bptjm-16	112	12	the	the	DET
bptjm-16	112	13	progression	progression	NOUN
bptjm-16	112	14	of	of	ADP
bptjm-16	112	15	autoimmune	autoimmune	ADJ
bptjm-16	112	16	diseases	disease	NOUN
bptjm-16	112	17	.	.	PUNCT
bptjm-16	113	1	necroptosis	necroptosis	NOUN
bptjm-16	113	2	in	in	ADP
bptjm-16	113	3	a	a	DET
bptjm-16	113	4	utoimmune	utoimmune	NOUN
bptjm-16	113	5	diseases	disease	NOUN
bptjm-16	113	6	the	the	DET
bptjm-16	113	7	examination	examination	NOUN
bptjm-16	113	8	of	of	ADP
bptjm-16	113	9	certain	certain	ADJ
bptjm-16	113	10	neurodegenerative	neurodegenerative	ADJ
bptjm-16	113	11	diseases	disease	NOUN
bptjm-16	113	12	,	,	PUNCT
bptjm-16	113	13	such	such	ADJ
bptjm-16	113	14	as	as	ADP
bptjm-16	113	15	alzheimer	alzheimer	PROPN
bptjm-16	113	16	’s	’s	PART
bptjm-16	113	17	disease	disease	NOUN
bptjm-16	113	18	(	(	PUNCT
bptjm-16	113	19	ad	ad	NOUN
bptjm-16	113	20	)	)	PUNCT
bptjm-16	113	21	,	,	PUNCT
bptjm-16	113	22	multiple	multiple	ADJ
bptjm-16	113	23	sclerosis	sclerosis	NOUN
bptjm-16	113	24	(	(	PUNCT
bptjm-16	113	25	ms	ms	NOUN
bptjm-16	113	26	)	)	PUNCT
bptjm-16	113	27	,	,	PUNCT
bptjm-16	113	28	and	and	CCONJ
bptjm-16	113	29	amyotrophic	amyotrophic	ADJ
bptjm-16	113	30	lateral	lateral	ADJ
bptjm-16	113	31	sclerosis	sclerosis	NOUN
bptjm-16	113	32	(	(	PUNCT
bptjm-16	113	33	als	als	NOUN
bptjm-16	113	34	)	)	PUNCT
bptjm-16	113	35	,	,	PUNCT
bptjm-16	113	36	have	have	AUX
bptjm-16	113	37	contributed	contribute	VERB
bptjm-16	113	38	to	to	ADP
bptjm-16	113	39	the	the	DET
bptjm-16	113	40	study	study	NOUN
bptjm-16	113	41	of	of	ADP
bptjm-16	113	42	the	the	DET
bptjm-16	113	43	implications	implication	NOUN
bptjm-16	113	44	of	of	ADP
bptjm-16	113	45	necroptosis71	necroptosis71	NOUN
bptjm-16	113	46	.	.	PUNCT
bptjm-16	114	1	alzheimer	alzheimer	PROPN
bptjm-16	114	2	’s	’s	PART
bptjm-16	114	3	disease	disease	NOUN
bptjm-16	114	4	(	(	PUNCT
bptjm-16	114	5	ad	ad	NOUN
bptjm-16	114	6	)	)	PUNCT
bptjm-16	114	7	is	be	AUX
bptjm-16	114	8	a	a	DET
bptjm-16	114	9	degenerative	degenerative	ADJ
bptjm-16	114	10	brain	brain	NOUN
bptjm-16	114	11	disease	disease	NOUN
bptjm-16	114	12	,	,	PUNCT
bptjm-16	114	13	which	which	PRON
bptjm-16	114	14	is	be	AUX
bptjm-16	114	15	characterized	characterize	VERB
bptjm-16	114	16	by	by	ADP
bptjm-16	114	17	the	the	DET
bptjm-16	114	18	damage	damage	NOUN
bptjm-16	114	19	and	and	CCONJ
bptjm-16	114	20	loss	loss	NOUN
bptjm-16	114	21	of	of	ADP
bptjm-16	114	22	neurons	neuron	NOUN
bptjm-16	114	23	.	.	PUNCT
bptjm-16	115	1	a	a	DET
bptjm-16	115	2	study	study	NOUN
bptjm-16	115	3	examining	examine	VERB
bptjm-16	115	4	human	human	ADJ
bptjm-16	115	5	ad	ad	NOUN
bptjm-16	115	6	brains	brain	NOUN
bptjm-16	115	7	and	and	CCONJ
bptjm-16	115	8	mouse	mouse	NOUN
bptjm-16	115	9	model	model	NOUN
bptjm-16	115	10	ad	ad	NOUN
bptjm-16	115	11	brains72	brains72	NOUN
bptjm-16	115	12	con	con	PROPN
bptjm-16	115	13	rmed	rme	VERB
bptjm-16	115	14	the	the	DET
bptjm-16	115	15	activation	activation	NOUN
bptjm-16	115	16	of	of	ADP
bptjm-16	115	17	necroptosis73	necroptosis73	NOUN
bptjm-16	115	18	after	after	ADP
bptjm-16	115	19	observing	observe	VERB
bptjm-16	115	20	a	a	DET
bptjm-16	115	21	major	major	ADJ
bptjm-16	115	22	increase	increase	NOUN
bptjm-16	115	23	in	in	ADP
bptjm-16	115	24	the	the	DET
bptjm-16	115	25	level	level	NOUN
bptjm-16	115	26	of	of	ADP
bptjm-16	115	27	necroptosis	necroptosis	NOUN
bptjm-16	115	28	markers	marker	NOUN
bptjm-16	115	29	—	—	PUNCT
bptjm-16	115	30	ripk1	ripk1	NOUN
bptjm-16	115	31	,	,	PUNCT
bptjm-16	115	32	mlkl	mlkl	ADJ
bptjm-16	115	33	,	,	PUNCT
bptjm-16	115	34	necrosome	necrosome	NOUN
bptjm-16	115	35	complex	complex	NOUN
bptjm-16	115	36	and	and	CCONJ
bptjm-16	115	37	mlkl	mlkl	VERB
bptjm-16	115	38	oligomers	oligomer	NOUN
bptjm-16	115	39	—	—	PUNCT
bptjm-16	115	40	in	in	ADP
bptjm-16	115	41	ad	ad	NOUN
bptjm-16	115	42	brains	brain	NOUN
bptjm-16	115	43	compared	compare	VERB
bptjm-16	115	44	to	to	ADP
bptjm-16	115	45	normal	normal	ADJ
bptjm-16	115	46	.	.	PUNCT
bptjm-16	116	1	subsequently	subsequently	ADV
bptjm-16	116	2	treating	treat	VERB
bptjm-16	116	3	mice	mouse	NOUN
bptjm-16	116	4	with	with	ADP
bptjm-16	116	5	ad	ad	NOUN
bptjm-16	116	6	brains	brain	NOUN
bptjm-16	116	7	with	with	ADP
bptjm-16	116	8	the	the	DET
bptjm-16	116	9	necroptosis	necroptosis	NOUN
bptjm-16	116	10	inhibitor	inhibitor	NOUN
bptjm-16	116	11	,	,	PUNCT
bptjm-16	116	12	cl	cl	NOUN
bptjm-16	116	13	-	-	ADJ
bptjm-16	116	14	o	o	NOUN
bptjm-16	116	15	-	-	NOUN
bptjm-16	116	16	necrostatin	necrostatin	ADJ
bptjm-16	116	17	,	,	PUNCT
bptjm-16	116	18	signi	signi	ADJ
bptjm-16	116	19	cantly	cantly	ADV
bptjm-16	116	20	suppressed	suppress	VERB
bptjm-16	116	21	necroptosis	necroptosis	NOUN
bptjm-16	116	22	and	and	CCONJ
bptjm-16	116	23	prevented	prevent	VERB
bptjm-16	116	24	neuronal	neuronal	ADJ
bptjm-16	116	25	loss73	loss73	NOUN
bptjm-16	116	26	.	.	PUNCT
bptjm-16	117	1	this	this	PRON
bptjm-16	117	2	suggests	suggest	VERB
bptjm-16	117	3	that	that	SCONJ
bptjm-16	117	4	inhibiting	inhibit	VERB
bptjm-16	117	5	the	the	DET
bptjm-16	117	6	function	function	NOUN
bptjm-16	117	7	of	of	ADP
bptjm-16	117	8	necrosome	necrosome	ADJ
bptjm-16	117	9	components	component	NOUN
bptjm-16	117	10	interferes	interfere	VERB
bptjm-16	117	11	with	with	ADP
bptjm-16	117	12	the	the	DET
bptjm-16	117	13	activation	activation	NOUN
bptjm-16	117	14	of	of	ADP
bptjm-16	117	15	necroptosis	necroptosis	NOUN
bptjm-16	117	16	,	,	PUNCT
bptjm-16	117	17	highlighting	highlight	VERB
bptjm-16	117	18	a	a	DET
bptjm-16	117	19	promising	promising	ADJ
bptjm-16	117	20	strategy	strategy	NOUN
bptjm-16	117	21	in	in	ADP
bptjm-16	117	22	the	the	DET
bptjm-16	117	23	treatment	treatment	NOUN
bptjm-16	117	24	of	of	ADP
bptjm-16	117	25	ad	ad	NOUN
bptjm-16	117	26	.	.	PUNCT
bptjm-16	118	1	in	in	ADP
bptjm-16	118	2	some	some	DET
bptjm-16	118	3	reports	report	NOUN
bptjm-16	118	4	,	,	PUNCT
bptjm-16	118	5	apoptotic	apoptotic	ADJ
bptjm-16	118	6	morphology	morphology	NOUN
bptjm-16	118	7	was	be	AUX
bptjm-16	118	8	not	not	PART
bptjm-16	118	9	directly	directly	ADV
bptjm-16	118	10	observed	observe	VERB
bptjm-16	118	11	in	in	ADP
bptjm-16	118	12	any	any	DET
bptjm-16	118	13	sections	section	NOUN
bptjm-16	118	14	of	of	ADP
bptjm-16	118	15	the	the	DET
bptjm-16	118	16	brain	brain	NOUN
bptjm-16	118	17	.	.	PUNCT
bptjm-16	119	1	instead	instead	ADV
bptjm-16	119	2	,	,	PUNCT
bptjm-16	119	3	the	the	DET
bptjm-16	119	4	cells	cell	NOUN
bptjm-16	119	5	showed	show	VERB
bptjm-16	119	6	swollen	swollen	ADJ
bptjm-16	119	7	morphologies	morphology	NOUN
bptjm-16	119	8	and	and	CCONJ
bptjm-16	119	9	were	be	AUX
bptjm-16	119	10	positive	positive	ADJ
bptjm-16	119	11	for	for	ADP
bptjm-16	119	12	dna	dna	PROPN
bptjm-16	119	13	fragmentation	fragmentation	NOUN
bptjm-16	119	14	,	,	PUNCT
bptjm-16	119	15	implying	imply	VERB
bptjm-16	119	16	that	that	SCONJ
bptjm-16	119	17	ad	ad	NOUN
bptjm-16	119	18	pathogenesis	pathogenesis	NOUN
bptjm-16	119	19	may	may	AUX
bptjm-16	119	20	not	not	PART
bptjm-16	119	21	involve	involve	VERB
bptjm-16	119	22	apoptosis	apoptosis	NOUN
bptjm-16	119	23	.	.	PUNCT
bptjm-16	120	1	others	other	NOUN
bptjm-16	120	2	have	have	AUX
bptjm-16	120	3	argued	argue	VERB
bptjm-16	120	4	that	that	SCONJ
bptjm-16	120	5	the	the	DET
bptjm-16	120	6	apoptosis	apoptosis	NOUN
bptjm-16	120	7	theory	theory	NOUN
bptjm-16	120	8	and	and	CCONJ
bptjm-16	120	9	the	the	DET
bptjm-16	120	10	clinical	clinical	ADJ
bptjm-16	120	11	manifestations	manifestation	NOUN
bptjm-16	120	12	contradict	contradict	VERB
bptjm-16	120	13	each	each	DET
bptjm-16	120	14	other	other	ADJ
bptjm-16	120	15	.	.	PUNCT
bptjm-16	121	1	cells	cell	NOUN
bptjm-16	121	2	directed	direct	VERB
bptjm-16	121	3	to	to	ADP
bptjm-16	121	4	apoptosis	apoptosis	NOUN
bptjm-16	121	5	have	have	AUX
bptjm-16	121	6	shown	show	VERB
bptjm-16	121	7	to	to	PART
bptjm-16	121	8	die	die	VERB
bptjm-16	121	9	within	within	ADP
bptjm-16	121	10	days	day	NOUN
bptjm-16	121	11	,	,	PUNCT
bptjm-16	121	12	and	and	CCONJ
bptjm-16	121	13	with	with	ADP
bptjm-16	121	14	great	great	ADJ
bptjm-16	121	15	levels	level	NOUN
bptjm-16	121	16	of	of	ADP
bptjm-16	121	17	caspase-3	caspase-3	NUM
bptjm-16	121	18	activity	activity	NOUN
bptjm-16	121	19	,	,	PUNCT
bptjm-16	121	20	suggesting	suggest	VERB
bptjm-16	121	21	an	an	DET
bptjm-16	121	22	acute	acute	ADJ
bptjm-16	121	23	and	and	CCONJ
bptjm-16	121	24	massive	massive	ADJ
bptjm-16	121	25	neuronal	neuronal	ADJ
bptjm-16	121	26	loss	loss	NOUN
bptjm-16	121	27	according	accord	VERB
bptjm-16	121	28	to	to	ADP
bptjm-16	121	29	the	the	DET
bptjm-16	121	30	apoptosis	apoptosis	NOUN
bptjm-16	121	31	theory	theory	NOUN
bptjm-16	121	32	.	.	PUNCT
bptjm-16	122	1	in	in	ADP
bptjm-16	122	2	such	such	ADJ
bptjm-16	122	3	cases	case	NOUN
bptjm-16	122	4	,	,	PUNCT
bptjm-16	122	5	the	the	DET
bptjm-16	122	6	clinical	clinical	ADJ
bptjm-16	122	7	symptoms	symptom	NOUN
bptjm-16	122	8	of	of	ADP
bptjm-16	122	9	ad	ad	NOUN
bptjm-16	122	10	patients	patient	NOUN
bptjm-16	122	11	should	should	AUX
bptjm-16	122	12	be	be	AUX
bptjm-16	122	13	observed	observe	VERB
bptjm-16	122	14	in	in	ADP
bptjm-16	122	15	the	the	DET
bptjm-16	122	16	early	early	ADJ
bptjm-16	122	17	phase	phase	NOUN
bptjm-16	122	18	of	of	ADP
bptjm-16	122	19	the	the	DET
bptjm-16	122	20	disease	disease	NOUN
bptjm-16	122	21	rather	rather	ADV
bptjm-16	122	22	than	than	ADP
bptjm-16	122	23	berkeley	berkeley	PROPN
bptjm-16	122	24	pharma	pharma	PROPN
bptjm-16	122	25	tech	tech	NOUN
bptjm-16	122	26	journal	journal	NOUN
bptjm-16	122	27	of	of	ADP
bptjm-16	122	28	medicine	medicine	NOUN
bptjm-16	122	29	|	|	ADV
bptjm-16	122	30	104	104	NUM
bptjm-16	122	31	assessing	assess	VERB
bptjm-16	122	32	the	the	DET
bptjm-16	122	33	progression	progression	NOUN
bptjm-16	122	34	of	of	ADP
bptjm-16	122	35	the	the	DET
bptjm-16	122	36	disease	disease	NOUN
bptjm-16	122	37	over	over	ADP
bptjm-16	122	38	a	a	DET
bptjm-16	122	39	decade	decade	NOUN
bptjm-16	122	40	.	.	PUNCT
bptjm-16	123	1	amyotrophic	amyotrophic	ADJ
bptjm-16	123	2	lateral	lateral	ADJ
bptjm-16	123	3	sclerosis	sclerosis	NOUN
bptjm-16	123	4	(	(	PUNCT
bptjm-16	123	5	als	als	NOUN
bptjm-16	123	6	)	)	PUNCT
bptjm-16	123	7	is	be	AUX
bptjm-16	123	8	a	a	DET
bptjm-16	123	9	progressive	progressive	ADJ
bptjm-16	123	10	neurodegenerative	neurodegenerative	ADJ
bptjm-16	123	11	disease	disease	NOUN
bptjm-16	123	12	characterized	characterize	VERB
bptjm-16	123	13	by	by	ADP
bptjm-16	123	14	the	the	DET
bptjm-16	123	15	loss	loss	NOUN
bptjm-16	123	16	of	of	ADP
bptjm-16	123	17	motor	motor	NOUN
bptjm-16	123	18	neurons	neuron	NOUN
bptjm-16	123	19	.	.	PUNCT
bptjm-16	124	1	compared	compare	VERB
bptjm-16	124	2	to	to	ADP
bptjm-16	124	3	healthy	healthy	ADJ
bptjm-16	124	4	control	control	NOUN
bptjm-16	124	5	spinal	spinal	ADJ
bptjm-16	124	6	cords	cord	NOUN
bptjm-16	124	7	,	,	PUNCT
bptjm-16	124	8	the	the	DET
bptjm-16	124	9	als	als	NOUN
bptjm-16	124	10	spinal	spinal	ADJ
bptjm-16	124	11	cords	cord	NOUN
bptjm-16	124	12	showed	show	VERB
bptjm-16	124	13	an	an	DET
bptjm-16	124	14	increase	increase	NOUN
bptjm-16	124	15	in	in	ADP
bptjm-16	124	16	necrosome	necrosome	ADJ
bptjm-16	124	17	components	component	NOUN
bptjm-16	124	18	,	,	PUNCT
bptjm-16	124	19	including	include	VERB
bptjm-16	124	20	ripk1	ripk1	NOUN
bptjm-16	124	21	,	,	PUNCT
bptjm-16	124	22	ripk3	ripk3	NOUN
bptjm-16	124	23	and	and	CCONJ
bptjm-16	124	24	mlkl	mlkl	VERB
bptjm-16	124	25	,	,	PUNCT
bptjm-16	124	26	in	in	ADP
bptjm-16	124	27	a	a	DET
bptjm-16	124	28	mouse	mouse	NOUN
bptjm-16	124	29	model	model	NOUN
bptjm-16	124	30	of	of	ADP
bptjm-16	124	31	als15	als15	PROPN
bptjm-16	124	32	.	.	PUNCT
bptjm-16	125	1	furthermore	furthermore	ADV
bptjm-16	125	2	,	,	PUNCT
bptjm-16	125	3	inhibiting	inhibit	VERB
bptjm-16	125	4	ripk1	ripk1	NOUN
bptjm-16	125	5	with	with	ADP
bptjm-16	125	6	nec-1	nec-1	PRON
bptjm-16	125	7	,	,	PUNCT
bptjm-16	125	8	or	or	CCONJ
bptjm-16	125	9	knocking	knock	VERB
bptjm-16	125	10	-	-	PUNCT
bptjm-16	125	11	out	out	ADP
bptjm-16	125	12	ripk3	ripk3	NOUN
bptjm-16	125	13	,	,	PUNCT
bptjm-16	125	14	protected	protect	VERB
bptjm-16	125	15	against	against	ADP
bptjm-16	125	16	demyelination	demyelination	NOUN
bptjm-16	125	17	and	and	CCONJ
bptjm-16	125	18	prevented	prevent	VERB
bptjm-16	125	19	the	the	DET
bptjm-16	125	20	progression	progression	NOUN
bptjm-16	125	21	of	of	ADP
bptjm-16	125	22	the	the	DET
bptjm-16	125	23	disease15	disease15	NOUN
bptjm-16	125	24	.	.	PUNCT
bptjm-16	126	1	thus	thus	ADV
bptjm-16	126	2	,	,	PUNCT
bptjm-16	126	3	through	through	ADP
bptjm-16	126	4	promoting	promote	VERB
bptjm-16	126	5	in	in	ADP
bptjm-16	126	6	ammation	ammation	NOUN
bptjm-16	126	7	and	and	CCONJ
bptjm-16	126	8	cell	cell	NOUN
bptjm-16	126	9	death	death	NOUN
bptjm-16	126	10	,	,	PUNCT
bptjm-16	126	11	ripk1	ripk1	NOUN
bptjm-16	126	12	and	and	CCONJ
bptjm-16	126	13	ripk3	ripk3	NOUN
bptjm-16	126	14	induce	induce	VERB
bptjm-16	126	15	axonal	axonal	ADJ
bptjm-16	126	16	degradation	degradation	NOUN
bptjm-16	126	17	and	and	CCONJ
bptjm-16	126	18	act	act	NOUN
bptjm-16	126	19	as	as	ADP
bptjm-16	126	20	mediators	mediator	NOUN
bptjm-16	126	21	of	of	ADP
bptjm-16	126	22	als	al	NOUN
bptjm-16	126	23	and	and	CCONJ
bptjm-16	126	24	pd	pd	PROPN
bptjm-16	126	25	.	.	PUNCT
bptjm-16	127	1	this	this	PRON
bptjm-16	127	2	further	far	ADV
bptjm-16	127	3	indicates	indicate	VERB
bptjm-16	127	4	that	that	SCONJ
bptjm-16	127	5	,	,	PUNCT
bptjm-16	127	6	since	since	SCONJ
bptjm-16	127	7	necroptosis	necroptosis	NOUN
bptjm-16	127	8	is	be	AUX
bptjm-16	127	9	activated	activate	VERB
bptjm-16	127	10	in	in	ADP
bptjm-16	127	11	als	al	NOUN
bptjm-16	127	12	,	,	PUNCT
bptjm-16	127	13	inhibition	inhibition	NOUN
bptjm-16	127	14	of	of	ADP
bptjm-16	127	15	necroptosis	necroptosis	NOUN
bptjm-16	127	16	can	can	AUX
bptjm-16	127	17	be	be	AUX
bptjm-16	127	18	a	a	DET
bptjm-16	127	19	potential	potential	ADJ
bptjm-16	127	20	therapeutic	therapeutic	ADJ
bptjm-16	127	21	target	target	NOUN
bptjm-16	127	22	for	for	ADP
bptjm-16	127	23	this	this	DET
bptjm-16	127	24	disease	disease	NOUN
bptjm-16	127	25	.	.	PUNCT
bptjm-16	128	1	additionally	additionally	ADV
bptjm-16	128	2	,	,	PUNCT
bptjm-16	128	3	a	a	DET
bptjm-16	128	4	study	study	NOUN
bptjm-16	128	5	observing	observe	VERB
bptjm-16	128	6	a	a	DET
bptjm-16	128	7	parkinson	parkinson	NOUN
bptjm-16	128	8	's	's	PART
bptjm-16	128	9	disease	disease	NOUN
bptjm-16	128	10	(	(	PUNCT
bptjm-16	128	11	pd	pd	NOUN
bptjm-16	128	12	)	)	PUNCT
bptjm-16	128	13	model	model	NOUN
bptjm-16	128	14	found	find	VERB
bptjm-16	128	15	that	that	SCONJ
bptjm-16	128	16	upon	upon	SCONJ
bptjm-16	128	17	inhibition	inhibition	NOUN
bptjm-16	128	18	of	of	ADP
bptjm-16	128	19	ripk1	ripk1	NOUN
bptjm-16	128	20	by	by	ADP
bptjm-16	128	21	nec-113	nec-113	ADJ
bptjm-16	128	22	neuronal	neuronal	ADJ
bptjm-16	128	23	degradation	degradation	NOUN
bptjm-16	128	24	was	be	AUX
bptjm-16	128	25	reduced	reduce	VERB
bptjm-16	128	26	by	by	ADP
bptjm-16	128	27	a	a	DET
bptjm-16	128	28	half	half	NOUN
bptjm-16	128	29	,	,	PUNCT
bptjm-16	128	30	compared	compare	VERB
bptjm-16	128	31	to	to	ADP
bptjm-16	128	32	untreated	untreated	ADJ
bptjm-16	128	33	cells	cell	NOUN
bptjm-16	128	34	.	.	PUNCT
bptjm-16	129	1	the	the	DET
bptjm-16	129	2	protective	protective	ADJ
bptjm-16	129	3	e	e	X
bptjm-16	129	4	ect	ect	X
bptjm-16	129	5	of	of	ADP
bptjm-16	129	6	nec-1	nec-1	PRON
bptjm-16	129	7	indicates	indicate	VERB
bptjm-16	129	8	the	the	DET
bptjm-16	129	9	therapeutic	therapeutic	ADJ
bptjm-16	129	10	potential	potential	NOUN
bptjm-16	129	11	of	of	ADP
bptjm-16	129	12	this	this	DET
bptjm-16	129	13	drug	drug	NOUN
bptjm-16	129	14	in	in	ADP
bptjm-16	129	15	als	als	NOUN
bptjm-16	129	16	and	and	CCONJ
bptjm-16	129	17	pd	pd	PROPN
bptjm-16	129	18	.	.	PUNCT
bptjm-16	130	1	the	the	DET
bptjm-16	130	2	study	study	NOUN
bptjm-16	130	3	used	use	VERB
bptjm-16	130	4	a	a	DET
bptjm-16	130	5	human	human	PROPN
bptjm-16	130	6	ipsc	ipsc	PROPN
bptjm-16	130	7	based	base	VERB
bptjm-16	130	8	model	model	NOUN
bptjm-16	130	9	to	to	AUX
bptjm-16	130	10	e	e	NOUN
bptjm-16	130	11	ectively	ectively	ADV
bptjm-16	130	12	capture	capture	VERB
bptjm-16	130	13	both	both	CCONJ
bptjm-16	130	14	early	early	ADJ
bptjm-16	130	15	pathological	pathological	ADJ
bptjm-16	130	16	events	event	NOUN
bptjm-16	130	17	in	in	ADP
bptjm-16	130	18	mutant	mutant	ADJ
bptjm-16	130	19	neural	neural	ADJ
bptjm-16	130	20	cells	cell	NOUN
bptjm-16	130	21	and	and	CCONJ
bptjm-16	130	22	the	the	DET
bptjm-16	130	23	bene	bene	PROPN
bptjm-16	130	24	cial	cial	NOUN
bptjm-16	130	25	e	e	NOUN
bptjm-16	130	26	ects	ect	NOUN
bptjm-16	130	27	of	of	ADP
bptjm-16	130	28	blocking	blocking	NOUN
bptjm-16	130	29	necroptosis	necroptosis	NOUN
bptjm-16	130	30	,	,	PUNCT
bptjm-16	130	31	thereby	thereby	ADV
bptjm-16	130	32	,	,	PUNCT
bptjm-16	130	33	strengthening	strengthen	VERB
bptjm-16	130	34	the	the	DET
bptjm-16	130	35	validity	validity	NOUN
bptjm-16	130	36	of	of	ADP
bptjm-16	130	37	the	the	DET
bptjm-16	130	38	results	result	NOUN
bptjm-16	130	39	.	.	PUNCT
bptjm-16	131	1	multiple	multiple	ADJ
bptjm-16	131	2	sclerosis	sclerosis	NOUN
bptjm-16	131	3	(	(	PUNCT
bptjm-16	131	4	ms	ms	NOUN
bptjm-16	131	5	)	)	PUNCT
bptjm-16	131	6	is	be	AUX
bptjm-16	131	7	a	a	DET
bptjm-16	131	8	chronic	chronic	ADJ
bptjm-16	131	9	neurodegenerative	neurodegenerative	ADJ
bptjm-16	131	10	disease	disease	NOUN
bptjm-16	131	11	characterized	characterize	VERB
bptjm-16	131	12	by	by	ADP
bptjm-16	131	13	the	the	DET
bptjm-16	131	14	loss	loss	NOUN
bptjm-16	131	15	of	of	ADP
bptjm-16	131	16	oligodendrocytes	oligodendrocyte	NOUN
bptjm-16	131	17	and	and	CCONJ
bptjm-16	131	18	demyelination	demyelination	NOUN
bptjm-16	131	19	.	.	PUNCT
bptjm-16	132	1	high	high	ADJ
bptjm-16	132	2	concentrations	concentration	NOUN
bptjm-16	132	3	of	of	ADP
bptjm-16	132	4	necroptosis	necroptosis	NOUN
bptjm-16	132	5	components	component	NOUN
bptjm-16	132	6	,	,	PUNCT
bptjm-16	132	7	including	include	VERB
bptjm-16	132	8	phosphorylation	phosphorylation	NOUN
bptjm-16	132	9	of	of	ADP
bptjm-16	132	10	ripk1	ripk1	NOUN
bptjm-16	132	11	,	,	PUNCT
bptjm-16	132	12	ripk3	ripk3	NOUN
bptjm-16	132	13	and	and	CCONJ
bptjm-16	132	14	mlkl	mlkl	NUM
bptjm-16	132	15	,	,	PUNCT
bptjm-16	132	16	were	be	AUX
bptjm-16	132	17	detected	detect	VERB
bptjm-16	132	18	in	in	ADP
bptjm-16	132	19	pathological	pathological	ADJ
bptjm-16	132	20	samples	sample	NOUN
bptjm-16	132	21	from	from	ADP
bptjm-16	132	22	ms	ms	ADJ
bptjm-16	132	23	patients	patient	NOUN
bptjm-16	132	24	,	,	PUNCT
bptjm-16	132	25	as	as	ADV
bptjm-16	132	26	well	well	ADV
bptjm-16	132	27	as	as	ADP
bptjm-16	132	28	a	a	DET
bptjm-16	132	29	prominent	prominent	ADJ
bptjm-16	132	30	increase	increase	NOUN
bptjm-16	132	31	of	of	ADP
bptjm-16	132	32	mlkl	mlkl	PROPN
bptjm-16	132	33	oligomers	oligomer	NOUN
bptjm-16	132	34	in	in	ADP
bptjm-16	132	35	ms	ms	ADJ
bptjm-16	132	36	pathological	pathological	ADJ
bptjm-16	132	37	samples	sample	NOUN
bptjm-16	132	38	compared	compare	VERB
bptjm-16	132	39	to	to	ADP
bptjm-16	132	40	the	the	DET
bptjm-16	132	41	control40	control40	NOUN
bptjm-16	132	42	.	.	PUNCT
bptjm-16	133	1	this	this	PRON
bptjm-16	133	2	indicates	indicate	VERB
bptjm-16	133	3	that	that	SCONJ
bptjm-16	133	4	necroptosis	necroptosis	NOUN
bptjm-16	133	5	is	be	AUX
bptjm-16	133	6	also	also	ADV
bptjm-16	133	7	involved	involve	VERB
bptjm-16	133	8	in	in	ADP
bptjm-16	133	9	the	the	DET
bptjm-16	133	10	pathogenesis	pathogenesis	NOUN
bptjm-16	133	11	of	of	ADP
bptjm-16	133	12	ms40	ms40	PROPN
bptjm-16	133	13	.	.	PUNCT
bptjm-16	134	1	in	in	ADP
bptjm-16	134	2	the	the	DET
bptjm-16	134	3	study	study	NOUN
bptjm-16	134	4	,	,	PUNCT
bptjm-16	134	5	oral	oral	ADJ
bptjm-16	134	6	administration	administration	NOUN
bptjm-16	134	7	of	of	ADP
bptjm-16	134	8	ripk1	ripk1	PROPN
bptjm-16	134	9	inhibitor	inhibitor	NOUN
bptjm-16	134	10	7	7	NUM
bptjm-16	134	11	-	-	PUNCT
bptjm-16	134	12	cl	cl	NOUN
bptjm-16	134	13	-	-	PUNCT
bptjm-16	134	14	o	o	NOUN
bptjm-16	134	15	nec-1	nec-1	ADV
bptjm-16	134	16	diminished	diminish	VERB
bptjm-16	134	17	oligodendrocyte	oligodendrocyte	ADJ
bptjm-16	134	18	degeneration	degeneration	NOUN
bptjm-16	134	19	and	and	CCONJ
bptjm-16	134	20	reduced	reduce	VERB
bptjm-16	134	21	the	the	DET
bptjm-16	134	22	disease	disease	NOUN
bptjm-16	134	23	severity	severity	NOUN
bptjm-16	134	24	in	in	ADP
bptjm-16	134	25	a	a	DET
bptjm-16	134	26	mouse	mouse	NOUN
bptjm-16	134	27	model	model	NOUN
bptjm-16	134	28	of	of	ADP
bptjm-16	134	29	ms	ms	PROPN
bptjm-16	134	30	40	40	NUM
bptjm-16	134	31	.	.	PUNCT
bptjm-16	135	1	these	these	DET
bptjm-16	135	2	ndings	nding	NOUN
bptjm-16	135	3	reveal	reveal	VERB
bptjm-16	135	4	that	that	SCONJ
bptjm-16	135	5	inhibiting	inhibit	VERB
bptjm-16	135	6	ripk1	ripk1	NOUN
bptjm-16	135	7	speci	speci	NOUN
bptjm-16	135	8	cally	cally	ADV
bptjm-16	135	9	could	could	AUX
bptjm-16	135	10	be	be	AUX
bptjm-16	135	11	of	of	ADP
bptjm-16	135	12	potential	potential	ADJ
bptjm-16	135	13	therapeutic	therapeutic	ADJ
bptjm-16	135	14	value	value	NOUN
bptjm-16	135	15	in	in	ADP
bptjm-16	135	16	the	the	DET
bptjm-16	135	17	treatment	treatment	NOUN
bptjm-16	135	18	of	of	ADP
bptjm-16	135	19	ms	ms	PROPN
bptjm-16	135	20	.	.	PROPN
bptjm-16	136	1	although	although	SCONJ
bptjm-16	136	2	the	the	DET
bptjm-16	136	3	study	study	NOUN
bptjm-16	136	4	does	do	AUX
bptjm-16	136	5	not	not	PART
bptjm-16	136	6	take	take	VERB
bptjm-16	136	7	into	into	ADP
bptjm-16	136	8	consideration	consideration	NOUN
bptjm-16	136	9	the	the	DET
bptjm-16	136	10	potential	potential	ADJ
bptjm-16	136	11	metabolic	metabolic	NOUN
bptjm-16	136	12	consequences	consequence	NOUN
bptjm-16	136	13	of	of	ADP
bptjm-16	136	14	orally	orally	ADV
bptjm-16	136	15	administering	administer	VERB
bptjm-16	136	16	the	the	DET
bptjm-16	136	17	drug	drug	NOUN
bptjm-16	136	18	,	,	PUNCT
bptjm-16	136	19	their	their	PRON
bptjm-16	136	20	results	result	NOUN
bptjm-16	136	21	and	and	CCONJ
bptjm-16	136	22	conclusion	conclusion	NOUN
bptjm-16	136	23	are	be	AUX
bptjm-16	136	24	strongly	strongly	ADV
bptjm-16	136	25	supported	support	VERB
bptjm-16	136	26	by	by	ADP
bptjm-16	136	27	signi	signi	NOUN
bptjm-16	136	28	ca	can	AUX
bptjm-16	136	29	nt	not	PART
bptjm-16	136	30	amounts	amount	NOUN
bptjm-16	136	31	of	of	ADP
bptjm-16	136	32	experimental	experimental	ADJ
bptjm-16	136	33	data	datum	NOUN
bptjm-16	136	34	.	.	PUNCT
bptjm-16	137	1	rheumatoid	rheumatoid	VERB
bptjm-16	137	2	arthritis	arthritis	NOUN
bptjm-16	137	3	(	(	PUNCT
bptjm-16	137	4	ra	ra	NOUN
bptjm-16	137	5	)	)	PUNCT
bptjm-16	137	6	is	be	AUX
bptjm-16	137	7	one	one	NUM
bptjm-16	137	8	of	of	ADP
bptjm-16	137	9	the	the	DET
bptjm-16	137	10	most	most	ADV
bptjm-16	137	11	common	common	ADJ
bptjm-16	137	12	chronic	chronic	NOUN
bptjm-16	137	13	in	in	ADP
bptjm-16	137	14	ammatory	ammatory	NOUN
bptjm-16	137	15	diseases	disease	NOUN
bptjm-16	137	16	that	that	PRON
bptjm-16	137	17	is	be	AUX
bptjm-16	137	18	characterized	characterize	VERB
bptjm-16	137	19	by	by	ADP
bptjm-16	137	20	joint	joint	NOUN
bptjm-16	137	21	in	in	ADP
bptjm-16	137	22	ammation	ammation	NOUN
bptjm-16	137	23	and	and	CCONJ
bptjm-16	137	24	osteoclastogenesis	osteoclastogenesis	NOUN
bptjm-16	137	25	.	.	PUNCT
bptjm-16	138	1	the	the	DET
bptjm-16	138	2	key	key	ADJ
bptjm-16	138	3	regulators	regulator	NOUN
bptjm-16	138	4	of	of	ADP
bptjm-16	138	5	necroptosis	necroptosis	NOUN
bptjm-16	138	6	,	,	PUNCT
bptjm-16	138	7	ripk1	ripk1	NOUN
bptjm-16	138	8	,	,	PUNCT
bptjm-16	138	9	ripk3	ripk3	NOUN
bptjm-16	138	10	and	and	CCONJ
bptjm-16	138	11	mlkl	mlkl	PROPN
bptjm-16	138	12	were	be	AUX
bptjm-16	138	13	detected	detect	VERB
bptjm-16	138	14	in	in	ADP
bptjm-16	138	15	signi	signi	ADJ
bptjm-16	138	16	cantly	cantly	ADV
bptjm-16	138	17	higher	high	ADJ
bptjm-16	138	18	amounts	amount	NOUN
bptjm-16	138	19	in	in	ADP
bptjm-16	138	20	the	the	DET
bptjm-16	138	21	synovium	synovium	NOUN
bptjm-16	138	22	of	of	ADP
bptjm-16	138	23	a	a	DET
bptjm-16	138	24	collagen	collagen	NOUN
bptjm-16	138	25	-	-	PUNCT
bptjm-16	138	26	induced	induce	VERB
bptjm-16	138	27	arthritis	arthritis	NOUN
bptjm-16	138	28	mouse	mouse	NOUN
bptjm-16	138	29	model	model	NOUN
bptjm-16	138	30	displayed	display	VERB
bptjm-16	138	31	signi	signi	ADJ
bptjm-16	138	32	cantly	cantly	ADV
bptjm-16	138	33	higher	high	ADJ
bptjm-16	138	34	berkeley	berkeley	PROPN
bptjm-16	138	35	pharma	pharma	PROPN
bptjm-16	138	36	tech	tech	NOUN
bptjm-16	138	37	journal	journal	NOUN
bptjm-16	138	38	of	of	ADP
bptjm-16	138	39	medicine	medicine	NOUN
bptjm-16	138	40	|	|	ADV
bptjm-16	138	41	105	105	NUM
bptjm-16	138	42	amounts	amount	NOUN
bptjm-16	138	43	of	of	ADP
bptjm-16	138	44	the	the	DET
bptjm-16	138	45	key	key	ADJ
bptjm-16	138	46	regulators	regulator	NOUN
bptjm-16	138	47	of	of	ADP
bptjm-16	138	48	necroptosis	necroptosis	NOUN
bptjm-16	138	49	,	,	PUNCT
bptjm-16	138	50	ripk1	ripk1	NOUN
bptjm-16	138	51	,	,	PUNCT
bptjm-16	138	52	ripk3	ripk3	NOUN
bptjm-16	138	53	and	and	CCONJ
bptjm-16	138	54	mlkl	mlkl	PROPN
bptjm-16	138	55	,	,	PUNCT
bptjm-16	138	56	which	which	PRON
bptjm-16	138	57	emphasized	emphasize	VERB
bptjm-16	138	58	the	the	DET
bptjm-16	138	59	involvement	involvement	NOUN
bptjm-16	138	60	of	of	ADP
bptjm-16	138	61	necroptosis	necroptosis	NOUN
bptjm-16	138	62	in	in	ADP
bptjm-16	138	63	the	the	DET
bptjm-16	138	64	pathogenesis	pathogenesis	NOUN
bptjm-16	138	65	of	of	ADP
bptjm-16	138	66	ra14	ra14	PROPN
bptjm-16	138	67	.	.	PUNCT
bptjm-16	139	1	in	in	ADP
bptjm-16	139	2	the	the	DET
bptjm-16	139	3	mouse	mouse	NOUN
bptjm-16	139	4	model	model	NOUN
bptjm-16	139	5	,	,	PUNCT
bptjm-16	139	6	ripk1	ripk1	ADJ
bptjm-16	139	7	inhibitor	inhibitor	NOUN
bptjm-16	139	8	nec-1	nec-1	ADV
bptjm-16	139	9	greatly	greatly	ADV
bptjm-16	139	10	suppressed	suppress	VERB
bptjm-16	139	11	the	the	DET
bptjm-16	139	12	expression	expression	NOUN
bptjm-16	139	13	of	of	ADP
bptjm-16	139	14	these	these	DET
bptjm-16	139	15	key	key	ADJ
bptjm-16	139	16	regulators	regulator	NOUN
bptjm-16	139	17	and	and	CCONJ
bptjm-16	139	18	the	the	DET
bptjm-16	139	19	main	main	ADJ
bptjm-16	139	20	in	in	ADP
bptjm-16	139	21	ammatory	ammatory	ADJ
bptjm-16	139	22	cytokines	cytokine	NOUN
bptjm-16	139	23	,	,	PUNCT
bptjm-16	139	24	il-17	il-17	X
bptjm-16	139	25	,	,	PUNCT
bptjm-16	139	26	il-1β	il-1β	PROPN
bptjm-16	139	27	,	,	PUNCT
bptjm-16	139	28	il-6	il-6	NOUN
bptjm-16	139	29	and	and	CCONJ
bptjm-16	139	30	tnfα74	tnfα74	NOUN
bptjm-16	139	31	.	.	PUNCT
bptjm-16	140	1	therefore	therefore	ADV
bptjm-16	140	2	,	,	PUNCT
bptjm-16	140	3	similarly	similarly	ADV
bptjm-16	140	4	to	to	ADP
bptjm-16	140	5	the	the	DET
bptjm-16	140	6	previous	previous	ADJ
bptjm-16	140	7	conclusions	conclusion	NOUN
bptjm-16	140	8	,	,	PUNCT
bptjm-16	140	9	this	this	DET
bptjm-16	140	10	study	study	NOUN
bptjm-16	140	11	supports	support	VERB
bptjm-16	140	12	the	the	DET
bptjm-16	140	13	potential	potential	NOUN
bptjm-16	140	14	of	of	ADP
bptjm-16	140	15	inhibiting	inhibit	VERB
bptjm-16	140	16	ripk1	ripk1	NOUN
bptjm-16	140	17	as	as	ADP
bptjm-16	140	18	a	a	DET
bptjm-16	140	19	novel	novel	ADJ
bptjm-16	140	20	therapeutic	therapeutic	ADJ
bptjm-16	140	21	approach	approach	NOUN
bptjm-16	140	22	for	for	ADP
bptjm-16	140	23	the	the	DET
bptjm-16	140	24	treatment	treatment	NOUN
bptjm-16	140	25	of	of	ADP
bptjm-16	140	26	ra	ra	PROPN
bptjm-16	140	27	.	.	PUNCT
bptjm-16	141	1	although	although	SCONJ
bptjm-16	141	2	these	these	DET
bptjm-16	141	3	studies	study	NOUN
bptjm-16	141	4	provide	provide	VERB
bptjm-16	141	5	compelling	compelling	ADJ
bptjm-16	141	6	evidence	evidence	NOUN
bptjm-16	141	7	for	for	ADP
bptjm-16	141	8	targeting	target	VERB
bptjm-16	141	9	ripk1	ripk1	NOUN
bptjm-16	141	10	and	and	CCONJ
bptjm-16	141	11	mlkl	mlkl	VERB
bptjm-16	141	12	molecules	molecule	NOUN
bptjm-16	141	13	for	for	ADP
bptjm-16	141	14	subsequent	subsequent	ADJ
bptjm-16	141	15	therapeutic	therapeutic	ADJ
bptjm-16	141	16	research	research	NOUN
bptjm-16	141	17	,	,	PUNCT
bptjm-16	141	18	a	a	DET
bptjm-16	141	19	close	close	ADJ
bptjm-16	141	20	examination	examination	NOUN
bptjm-16	141	21	of	of	ADP
bptjm-16	141	22	another	another	DET
bptjm-16	141	23	class	class	NOUN
bptjm-16	141	24	of	of	ADP
bptjm-16	141	25	proteins	protein	NOUN
bptjm-16	141	26	that	that	PRON
bptjm-16	141	27	play	play	VERB
bptjm-16	141	28	an	an	DET
bptjm-16	141	29	important	important	ADJ
bptjm-16	141	30	role	role	NOUN
bptjm-16	141	31	in	in	ADP
bptjm-16	141	32	necroptosis	necroptosis	NOUN
bptjm-16	141	33	may	may	AUX
bptjm-16	141	34	shed	shed	VERB
bptjm-16	141	35	light	light	NOUN
bptjm-16	141	36	on	on	ADP
bptjm-16	141	37	another	another	DET
bptjm-16	141	38	new	new	ADJ
bptjm-16	141	39	approach	approach	NOUN
bptjm-16	141	40	.	.	PUNCT
bptjm-16	142	1	inhibitors	inhibitor	NOUN
bptjm-16	142	2	of	of	ADP
bptjm-16	142	3	apoptosis	apoptosis	NOUN
bptjm-16	142	4	proteins	protein	NOUN
bptjm-16	142	5	(	(	PUNCT
bptjm-16	142	6	iaps	iap	NOUN
bptjm-16	142	7	)	)	PUNCT
bptjm-16	142	8	form	form	VERB
bptjm-16	142	9	a	a	DET
bptjm-16	142	10	family	family	NOUN
bptjm-16	142	11	of	of	ADP
bptjm-16	142	12	genetically	genetically	ADV
bptjm-16	142	13	conserved	conserve	VERB
bptjm-16	142	14	proteins	protein	NOUN
bptjm-16	142	15	characterized	characterize	VERB
bptjm-16	142	16	by	by	ADP
bptjm-16	142	17	the	the	DET
bptjm-16	142	18	presence	presence	NOUN
bptjm-16	142	19	of	of	ADP
bptjm-16	142	20	1	1	NUM
bptjm-16	142	21	-	-	SYM
bptjm-16	142	22	3	3	NUM
bptjm-16	142	23	baculovirus	baculovirus	NOUN
bptjm-16	142	24	iap	iap	PROPN
bptjm-16	142	25	repeat	repeat	PROPN
bptjm-16	142	26	(	(	PUNCT
bptjm-16	142	27	bir	bir	NOUN
bptjm-16	142	28	)	)	PUNCT
bptjm-16	142	29	motifs75	motifs75	NOUN
bptjm-16	142	30	.	.	PUNCT
bptjm-16	143	1	previous	previous	ADJ
bptjm-16	143	2	studies	study	NOUN
bptjm-16	143	3	have	have	VERB
bptjm-16	143	4	identi	identi	NOUN
bptjm-16	143	5	ed	ed	NOUN
bptjm-16	143	6	three	three	NUM
bptjm-16	143	7	family	family	NOUN
bptjm-16	143	8	members	member	NOUN
bptjm-16	143	9	(	(	PUNCT
bptjm-16	143	10	termed	term	VERB
bptjm-16	143	11	xiap	xiap	PROPN
bptjm-16	143	12	,	,	PUNCT
bptjm-16	143	13	ciap1	ciap1	PROPN
bptjm-16	143	14	,	,	PUNCT
bptjm-16	143	15	and	and	CCONJ
bptjm-16	143	16	ciap2	ciap2	NOUN
bptjm-16	143	17	)	)	PUNCT
bptjm-16	143	18	as	as	ADP
bptjm-16	143	19	potent	potent	ADJ
bptjm-16	143	20	suppressors	suppressor	NOUN
bptjm-16	143	21	of	of	ADP
bptjm-16	143	22	cell	cell	NOUN
bptjm-16	143	23	death	death	NOUN
bptjm-16	143	24	.	.	PUNCT
bptjm-16	144	1	xiap	xiap	PROPN
bptjm-16	144	2	,	,	PUNCT
bptjm-16	144	3	the	the	DET
bptjm-16	144	4	most	most	ADV
bptjm-16	144	5	-	-	PUNCT
bptjm-16	144	6	studied	study	VERB
bptjm-16	144	7	iap	iap	PROPN
bptjm-16	144	8	,	,	PUNCT
bptjm-16	144	9	inhibits	inhibit	VERB
bptjm-16	144	10	apoptosis	apoptosis	NOUN
bptjm-16	144	11	by	by	ADP
bptjm-16	144	12	binding	bind	VERB
bptjm-16	144	13	and	and	CCONJ
bptjm-16	144	14	inhibiting	inhibit	VERB
bptjm-16	144	15	caspases	caspase	NOUN
bptjm-16	144	16	,	,	PUNCT
bptjm-16	144	17	and	and	CCONJ
bptjm-16	144	18	it	it	PRON
bptjm-16	144	19	has	have	AUX
bptjm-16	144	20	been	be	AUX
bptjm-16	144	21	broadly	broadly	ADV
bptjm-16	144	22	assumed	assume	VERB
bptjm-16	144	23	that	that	SCONJ
bptjm-16	144	24	ciap1	ciap1	PROPN
bptjm-16	144	25	and	and	CCONJ
bptjm-16	144	26	ciap2	ciap2	NOUN
bptjm-16	144	27	block	block	NOUN
bptjm-16	144	28	apoptosis	apoptosis	NOUN
bptjm-16	144	29	through	through	ADP
bptjm-16	144	30	a	a	DET
bptjm-16	144	31	similar	similar	ADJ
bptjm-16	144	32	mechanism	mechanism	NOUN
bptjm-16	144	33	.	.	PUNCT
bptjm-16	145	1	however	however	ADV
bptjm-16	145	2	,	,	PUNCT
bptjm-16	145	3	recent	recent	ADJ
bptjm-16	145	4	structure	structure	NOUN
bptjm-16	145	5	function	function	NOUN
bptjm-16	145	6	analyses	analysis	NOUN
bptjm-16	145	7	have	have	AUX
bptjm-16	145	8	indicated	indicate	VERB
bptjm-16	145	9	that	that	SCONJ
bptjm-16	145	10	these	these	DET
bptjm-16	145	11	iaps	iap	NOUN
bptjm-16	145	12	are	be	AUX
bptjm-16	145	13	not	not	PART
bptjm-16	145	14	direct	direct	ADJ
bptjm-16	145	15	caspase	caspase	NOUN
bptjm-16	145	16	inhibitors	inhibitor	NOUN
bptjm-16	145	17	,	,	PUNCT
bptjm-16	145	18	suggesting	suggest	VERB
bptjm-16	145	19	that	that	SCONJ
bptjm-16	145	20	their	their	PRON
bptjm-16	145	21	anti	anti	ADJ
bptjm-16	145	22	-	-	ADJ
bptjm-16	145	23	apoptotic	apoptotic	ADJ
bptjm-16	145	24	function	function	NOUN
bptjm-16	145	25	must	must	AUX
bptjm-16	145	26	involve	involve	VERB
bptjm-16	145	27	alternative	alternative	ADJ
bptjm-16	145	28	mechanisms75	mechanisms75	NOUN
bptjm-16	145	29	.	.	PUNCT
bptjm-16	146	1	cellular	cellular	ADJ
bptjm-16	146	2	inhibitors	inhibitor	NOUN
bptjm-16	146	3	of	of	ADP
bptjm-16	146	4	apoptosis	apoptosis	NOUN
bptjm-16	146	5	inhibitors	inhibitor	NOUN
bptjm-16	146	6	of	of	ADP
bptjm-16	146	7	apoptosis	apoptosis	NOUN
bptjm-16	146	8	(	(	PUNCT
bptjm-16	146	9	iap	iap	PROPN
bptjm-16	146	10	)	)	PUNCT
bptjm-16	146	11	are	be	AUX
bptjm-16	146	12	proteins	protein	NOUN
bptjm-16	146	13	that	that	PRON
bptjm-16	146	14	belong	belong	VERB
bptjm-16	146	15	to	to	ADP
bptjm-16	146	16	the	the	DET
bptjm-16	146	17	family	family	NOUN
bptjm-16	146	18	of	of	ADP
bptjm-16	146	19	antiapoptotic	antiapoptotic	ADJ
bptjm-16	146	20	proteins	protein	NOUN
bptjm-16	146	21	that	that	PRON
bptjm-16	146	22	prevent	prevent	VERB
bptjm-16	146	23	cell	cell	NOUN
bptjm-16	146	24	death	death	NOUN
bptjm-16	146	25	,	,	PUNCT
bptjm-16	146	26	direct	direct	ADJ
bptjm-16	146	27	cell	cell	NOUN
bptjm-16	146	28	growth	growth	NOUN
bptjm-16	146	29	,	,	PUNCT
bptjm-16	146	30	and	and	CCONJ
bptjm-16	146	31	participate	participate	VERB
bptjm-16	146	32	in	in	ADP
bptjm-16	146	33	cellular	cellular	ADJ
bptjm-16	146	34	signal	signal	NOUN
bptjm-16	146	35	transduction76	transduction76	NOUN
bptjm-16	146	36	.	.	PUNCT
bptjm-16	147	1	the	the	DET
bptjm-16	147	2	mechanism	mechanism	NOUN
bptjm-16	147	3	of	of	ADP
bptjm-16	147	4	iaps	iap	NOUN
bptjm-16	147	5	in	in	ADP
bptjm-16	147	6	inhibiting	inhibit	VERB
bptjm-16	147	7	apoptosis	apoptosis	NOUN
bptjm-16	147	8	involves	involve	VERB
bptjm-16	147	9	both	both	CCONJ
bptjm-16	147	10	the	the	DET
bptjm-16	147	11	intrinsic	intrinsic	ADJ
bptjm-16	147	12	and	and	CCONJ
bptjm-16	147	13	extrinsic	extrinsic	ADJ
bptjm-16	147	14	apoptotic	apoptotic	ADJ
bptjm-16	147	15	pathways1	pathways1	NOUN
bptjm-16	147	16	.	.	PUNCT
bptjm-16	148	1	among	among	ADP
bptjm-16	148	2	these	these	DET
bptjm-16	148	3	iaps	iap	NOUN
bptjm-16	148	4	,	,	PUNCT
bptjm-16	148	5	cellular	cellular	ADJ
bptjm-16	148	6	iap1	iap1	NOUN
bptjm-16	148	7	and	and	CCONJ
bptjm-16	148	8	2	2	NUM
bptjm-16	148	9	(	(	PUNCT
bptjm-16	148	10	ciap1	ciap1	NOUN
bptjm-16	148	11	and	and	CCONJ
bptjm-16	148	12	ciap2	ciap2	PROPN
bptjm-16	148	13	)	)	PUNCT
bptjm-16	148	14	,	,	PUNCT
bptjm-16	148	15	the	the	DET
bptjm-16	148	16	key	key	ADJ
bptjm-16	148	17	molecules	molecule	NOUN
bptjm-16	148	18	of	of	ADP
bptjm-16	148	19	the	the	DET
bptjm-16	148	20	tumor	tumor	NOUN
bptjm-16	148	21	necrosis	necrosis	NOUN
bptjm-16	148	22	factor	factor	NOUN
bptjm-16	148	23	α	α	PROPN
bptjm-16	148	24	(	(	PUNCT
bptjm-16	148	25	tnfα	tnfα	NOUN
bptjm-16	148	26	)	)	PUNCT
bptjm-16	148	27	signaling	signal	VERB
bptjm-16	148	28	pathway	pathway	NOUN
bptjm-16	148	29	,	,	PUNCT
bptjm-16	148	30	are	be	AUX
bptjm-16	148	31	recruited	recruit	VERB
bptjm-16	148	32	upon	upon	SCONJ
bptjm-16	148	33	tnf	tnf	PROPN
bptjm-16	148	34	receptor	receptor	NOUN
bptjm-16	148	35	(	(	PUNCT
bptjm-16	148	36	tnf1	tnf1	NOUN
bptjm-16	148	37	)	)	PUNCT
bptjm-16	148	38	activation	activation	NOUN
bptjm-16	148	39	,	,	PUNCT
bptjm-16	148	40	along	along	ADP
bptjm-16	148	41	with	with	ADP
bptjm-16	148	42	the	the	DET
bptjm-16	148	43	other	other	ADJ
bptjm-16	148	44	adaptor	adaptor	NOUN
bptjm-16	148	45	proteins	protein	NOUN
bptjm-16	148	46	such	such	ADJ
bptjm-16	148	47	as	as	ADP
bptjm-16	148	48	tnf	tnf	PROPN
bptjm-16	148	49	receptor	receptor	NOUN
bptjm-16	148	50	-	-	PUNCT
bptjm-16	148	51	associated	associate	VERB
bptjm-16	148	52	factor	factor	NOUN
bptjm-16	148	53	(	(	PUNCT
bptjm-16	148	54	traf	traf	PROPN
bptjm-16	148	55	)	)	PUNCT
bptjm-16	148	56	,	,	PUNCT
bptjm-16	148	57	tnfrassociated	tnfrassociate	VERB
bptjm-16	148	58	death	death	NOUN
bptjm-16	148	59	domain	domain	NOUN
bptjm-16	148	60	protein	protein	NOUN
bptjm-16	148	61	(	(	PUNCT
bptjm-16	148	62	tradd	tradd	NOUN
bptjm-16	148	63	)	)	PUNCT
bptjm-16	148	64	,	,	PUNCT
bptjm-16	148	65	receptor	receptor	NOUN
bptjm-16	148	66	-	-	PUNCT
bptjm-16	148	67	interacting	interact	VERB
bptjm-16	148	68	protein	protein	NOUN
bptjm-16	148	69	kinase	kinase	NOUN
bptjm-16	148	70	1	1	NUM
bptjm-16	148	71	(	(	PUNCT
bptjm-16	148	72	ripk1	ripk1	NOUN
bptjm-16	148	73	)	)	PUNCT
bptjm-16	148	74	and	and	CCONJ
bptjm-16	148	75	linear	linear	ADJ
bptjm-16	148	76	ubiquitin	ubiquitin	NOUN
bptjm-16	148	77	chain	chain	NOUN
bptjm-16	148	78	assembly	assembly	NOUN
bptjm-16	148	79	complex	complex	NOUN
bptjm-16	148	80	(	(	PUNCT
bptjm-16	148	81	lubac	lubac	NOUN
bptjm-16	148	82	)	)	PUNCT
bptjm-16	148	83	.	.	PUNCT
bptjm-16	149	1	these	these	PRON
bptjm-16	149	2	then	then	ADV
bptjm-16	149	3	go	go	VERB
bptjm-16	149	4	on	on	ADP
bptjm-16	149	5	to	to	PART
bptjm-16	149	6	form	form	VERB
bptjm-16	149	7	the	the	DET
bptjm-16	149	8	signaling	signal	VERB
bptjm-16	149	9	complex	complex	NOUN
bptjm-16	149	10	i	i	PRON
bptjm-16	149	11	,	,	PUNCT
bptjm-16	149	12	which	which	PRON
bptjm-16	149	13	activates	activate	VERB
bptjm-16	149	14	the	the	DET
bptjm-16	149	15	nuclear	nuclear	ADJ
bptjm-16	149	16	factor	factor	NOUN
bptjm-16	149	17	kappa	kappa	PROPN
bptjm-16	149	18	b	b	PROPN
bptjm-16	149	19	(	(	PUNCT
bptjm-16	149	20	nf	nf	NOUN
bptjm-16	149	21	-	-	PUNCT
bptjm-16	149	22	κb	κb	NOUN
bptjm-16	149	23	)	)	PUNCT
bptjm-16	149	24	signaling	signal	VERB
bptjm-16	149	25	pathway	pathway	NOUN
bptjm-16	149	26	and	and	CCONJ
bptjm-16	149	27	promotes	promote	VERB
bptjm-16	149	28	cell	cell	NOUN
bptjm-16	149	29	survival77	survival77	NOUN
bptjm-16	149	30	.	.	PUNCT
bptjm-16	150	1	the	the	DET
bptjm-16	150	2	overexpression	overexpression	NOUN
bptjm-16	150	3	of	of	ADP
bptjm-16	150	4	the	the	DET
bptjm-16	150	5	iap	iap	PROPN
bptjm-16	150	6	protein	protein	NOUN
bptjm-16	150	7	family	family	NOUN
bptjm-16	150	8	has	have	AUX
bptjm-16	150	9	been	be	AUX
bptjm-16	150	10	reported	report	VERB
bptjm-16	150	11	to	to	PART
bptjm-16	150	12	be	be	AUX
bptjm-16	150	13	associated	associate	VERB
bptjm-16	150	14	with	with	ADP
bptjm-16	150	15	cancer	cancer	NOUN
bptjm-16	150	16	development	development	NOUN
bptjm-16	150	17	,	,	PUNCT
bptjm-16	150	18	with	with	ADP
bptjm-16	150	19	x	x	ADJ
bptjm-16	150	20	-	-	ADJ
bptjm-16	150	21	linked	link	VERB
bptjm-16	150	22	inhibitor	inhibitor	NOUN
bptjm-16	150	23	of	of	ADP
bptjm-16	150	24	apoptosis	apoptosis	NOUN
bptjm-16	150	25	protein	protein	NOUN
bptjm-16	150	26	(	(	PUNCT
bptjm-16	150	27	xiap	xiap	NOUN
bptjm-16	150	28	)	)	PUNCT
bptjm-16	150	29	classi	classi	PROPN
bptjm-16	150	30	ed	ed	NOUN
bptjm-16	150	31	as	as	ADP
bptjm-16	150	32	the	the	DET
bptjm-16	150	33	most	most	ADV
bptjm-16	150	34	potent	potent	ADJ
bptjm-16	150	35	iap	iap	PROPN
bptjm-16	150	36	family	family	NOUN
bptjm-16	150	37	member78	member78	NOUN
bptjm-16	150	38	.	.	PUNCT
bptjm-16	151	1	the	the	DET
bptjm-16	151	2	xiap	xiap	PROPN
bptjm-16	151	3	,	,	PUNCT
bptjm-16	151	4	ciap1	ciap1	PROPN
bptjm-16	151	5	,	,	PUNCT
bptjm-16	151	6	and	and	CCONJ
bptjm-16	151	7	ciap2	ciap2	NOUN
bptjm-16	151	8	contain	contain	VERB
bptjm-16	151	9	three	three	NUM
bptjm-16	151	10	baculovirus	baculovirus	NOUN
bptjm-16	151	11	berkeley	berkeley	PROPN
bptjm-16	151	12	pharma	pharma	PROPN
bptjm-16	151	13	tech	tech	NOUN
bptjm-16	151	14	journal	journal	NOUN
bptjm-16	151	15	of	of	ADP
bptjm-16	151	16	medicine	medicine	NOUN
bptjm-16	151	17	|	|	ADV
bptjm-16	151	18	106	106	NUM
bptjm-16	151	19	iap	iap	PROPN
bptjm-16	151	20	repeat	repeat	PROPN
bptjm-16	151	21	(	(	PUNCT
bptjm-16	151	22	bir	bir	NOUN
bptjm-16	151	23	)	)	PUNCT
bptjm-16	151	24	domains	domain	NOUN
bptjm-16	151	25	,	,	PUNCT
bptjm-16	151	26	a	a	DET
bptjm-16	151	27	ubiquitin	ubiquitin	NOUN
bptjm-16	151	28	-	-	PUNCT
bptjm-16	151	29	associated	associate	VERB
bptjm-16	151	30	(	(	PUNCT
bptjm-16	151	31	uba	uba	PROPN
bptjm-16	151	32	)	)	PUNCT
bptjm-16	151	33	domain	domain	NOUN
bptjm-16	151	34	,	,	PUNCT
bptjm-16	151	35	and	and	CCONJ
bptjm-16	151	36	a	a	DET
bptjm-16	151	37	newly	newly	ADV
bptjm-16	151	38	discovered	discover	VERB
bptjm-16	151	39	gene	gene	NOUN
bptjm-16	151	40	(	(	PUNCT
bptjm-16	151	41	ring	ring	NOUN
bptjm-16	151	42	)	)	PUNCT
bptjm-16	151	43	nger	nger	ADJ
bptjm-16	151	44	motif	motif	NOUN
bptjm-16	151	45	,	,	PUNCT
bptjm-16	151	46	which	which	PRON
bptjm-16	151	47	exhibits	exhibit	VERB
bptjm-16	151	48	ubiquitin	ubiquitin	ADJ
bptjm-16	151	49	e3	e3	NOUN
bptjm-16	151	50	ligase	ligase	PROPN
bptjm-16	151	51	activity79	activity79	PROPN
bptjm-16	151	52	.	.	PUNCT
bptjm-16	152	1	the	the	DET
bptjm-16	152	2	iaps	iap	NOUN
bptjm-16	152	3	prevent	prevent	VERB
bptjm-16	152	4	apoptosis	apoptosis	NOUN
bptjm-16	152	5	by	by	ADP
bptjm-16	152	6	inhibiting	inhibit	VERB
bptjm-16	152	7	downstream	downstream	ADJ
bptjm-16	152	8	caspases	caspase	NOUN
bptjm-16	152	9	,	,	PUNCT
bptjm-16	152	10	which	which	PRON
bptjm-16	152	11	are	be	AUX
bptjm-16	152	12	essential	essential	ADJ
bptjm-16	152	13	proteins	protein	NOUN
bptjm-16	152	14	of	of	ADP
bptjm-16	152	15	the	the	DET
bptjm-16	152	16	apoptotic	apoptotic	ADJ
bptjm-16	152	17	pathways	pathway	NOUN
bptjm-16	152	18	.	.	PUNCT
bptjm-16	153	1	the	the	DET
bptjm-16	153	2	cleaving	cleaving	NOUN
bptjm-16	153	3	of	of	ADP
bptjm-16	153	4	upstream	upstream	ADJ
bptjm-16	153	5	caspases	caspase	NOUN
bptjm-16	153	6	,	,	PUNCT
bptjm-16	153	7	such	such	ADJ
bptjm-16	153	8	as	as	ADP
bptjm-16	153	9	caspase	caspase	NOUN
bptjm-16	153	10	8	8	NUM
bptjm-16	153	11	and	and	CCONJ
bptjm-16	153	12	caspase	caspase	PROPN
bptjm-16	153	13	9	9	NUM
bptjm-16	153	14	,	,	PUNCT
bptjm-16	153	15	leads	lead	VERB
bptjm-16	153	16	to	to	ADP
bptjm-16	153	17	the	the	DET
bptjm-16	153	18	activation	activation	NOUN
bptjm-16	153	19	of	of	ADP
bptjm-16	153	20	downstream	downstream	ADJ
bptjm-16	153	21	e	e	PROPN
bptjm-16	153	22	ector	ector	PROPN
bptjm-16	153	23	caspases	caspase	NOUN
bptjm-16	153	24	,	,	PUNCT
bptjm-16	153	25	such	such	ADJ
bptjm-16	153	26	as	as	ADP
bptjm-16	153	27	caspase	caspase	NOUN
bptjm-16	153	28	3	3	NUM
bptjm-16	153	29	,	,	PUNCT
bptjm-16	153	30	eventually	eventually	ADV
bptjm-16	153	31	resulting	result	VERB
bptjm-16	153	32	in	in	ADP
bptjm-16	153	33	programmed	program	VERB
bptjm-16	153	34	cell	cell	NOUN
bptjm-16	153	35	death76	death76	NOUN
bptjm-16	153	36	.	.	PUNCT
bptjm-16	154	1	the	the	DET
bptjm-16	154	2	most	most	ADV
bptjm-16	154	3	recently	recently	ADV
bptjm-16	154	4	discovered	discover	VERB
bptjm-16	154	5	iap	iap	PROPN
bptjm-16	154	6	is	be	AUX
bptjm-16	154	7	the	the	DET
bptjm-16	154	8	mammalian	mammalian	ADJ
bptjm-16	154	9	iap	iap	PROPN
bptjm-16	154	10	ml	ml	PROPN
bptjm-16	154	11	-	-	PUNCT
bptjm-16	154	12	iap	iap	PROPN
bptjm-16	154	13	,	,	PUNCT
bptjm-16	154	14	which	which	PRON
bptjm-16	154	15	is	be	AUX
bptjm-16	154	16	detectable	detectable	ADJ
bptjm-16	154	17	in	in	ADP
bptjm-16	154	18	embryonic	embryonic	ADJ
bptjm-16	154	19	tissue	tissue	NOUN
bptjm-16	154	20	,	,	PUNCT
bptjm-16	154	21	certain	certain	ADJ
bptjm-16	154	22	adult	adult	NOUN
bptjm-16	154	23	tissues	tissue	NOUN
bptjm-16	154	24	and	and	CCONJ
bptjm-16	154	25	several	several	ADJ
bptjm-16	154	26	cancer	cancer	NOUN
bptjm-16	154	27	cell	cell	NOUN
bptjm-16	154	28	lines80	lines80	NOUN
bptjm-16	154	29	.	.	PUNCT
bptjm-16	155	1	although	although	SCONJ
bptjm-16	155	2	ml	ml	NOUN
bptjm-16	155	3	-	-	PUNCT
bptjm-16	155	4	iap	iap	PROPN
bptjm-16	155	5	has	have	VERB
bptjm-16	155	6	only	only	ADV
bptjm-16	155	7	one	one	NUM
bptjm-16	155	8	bir	bir	NOUN
bptjm-16	155	9	domain	domain	NOUN
bptjm-16	155	10	,	,	PUNCT
bptjm-16	155	11	it	it	PRON
bptjm-16	155	12	is	be	AUX
bptjm-16	155	13	reported	report	VERB
bptjm-16	155	14	to	to	PART
bptjm-16	155	15	inhibit	inhibit	VERB
bptjm-16	155	16	both	both	DET
bptjm-16	155	17	the	the	DET
bptjm-16	155	18	initiator	initiator	NOUN
bptjm-16	155	19	caspase	caspase	NOUN
bptjm-16	155	20	9	9	NUM
bptjm-16	156	1	and	and	CCONJ
bptjm-16	156	2	e	e	PROPN
bptjm-16	156	3	ector	ector	PROPN
bptjm-16	156	4	caspases	caspase	VERB
bptjm-16	156	5	3	3	NUM
bptjm-16	156	6	and	and	CCONJ
bptjm-16	156	7	7	7	NUM
bptjm-16	156	8	.	.	PUNCT
bptjm-16	157	1	thus	thus	ADV
bptjm-16	157	2	,	,	PUNCT
bptjm-16	157	3	it	it	PRON
bptjm-16	157	4	inhibits	inhibit	VERB
bptjm-16	157	5	cell	cell	NOUN
bptjm-16	157	6	death	death	NOUN
bptjm-16	157	7	induced	induce	VERB
bptjm-16	157	8	through	through	ADP
bptjm-16	157	9	death	death	NOUN
bptjm-16	157	10	receptors	receptor	NOUN
bptjm-16	157	11	by	by	ADP
bptjm-16	157	12	overexpression	overexpression	NOUN
bptjm-16	157	13	of	of	ADP
bptjm-16	157	14	the	the	DET
bptjm-16	157	15	cell	cell	NOUN
bptjm-16	157	16	death	death	NOUN
bptjm-16	157	17	pathway	pathway	NOUN
bptjm-16	157	18	proteins	protein	NOUN
bptjm-16	157	19	fadd	fadd	NOUN
bptjm-16	157	20	,	,	PUNCT
bptjm-16	157	21	bax	bax	PROPN
bptjm-16	157	22	,	,	PUNCT
bptjm-16	157	23	rip	rip	NOUN
bptjm-16	157	24	,	,	PUNCT
bptjm-16	157	25	rip3	rip3	PROPN
bptjm-16	157	26	and	and	CCONJ
bptjm-16	157	27	dr381	dr381	PROPN
bptjm-16	157	28	.	.	PUNCT
bptjm-16	158	1	in	in	ADP
bptjm-16	158	2	fact	fact	NOUN
bptjm-16	158	3	,	,	PUNCT
bptjm-16	158	4	the	the	DET
bptjm-16	158	5	most	most	ADV
bptjm-16	158	6	compelling	compelling	ADJ
bptjm-16	158	7	evidence	evidence	NOUN
bptjm-16	158	8	for	for	ADP
bptjm-16	158	9	the	the	DET
bptjm-16	158	10	regulation	regulation	NOUN
bptjm-16	158	11	of	of	ADP
bptjm-16	158	12	developmental	developmental	ADJ
bptjm-16	158	13	cell	cell	NOUN
bptjm-16	158	14	death	death	NOUN
bptjm-16	158	15	by	by	ADP
bptjm-16	158	16	iaps	iap	NOUN
bptjm-16	158	17	originates	originate	NOUN
bptjm-16	158	18	from	from	ADP
bptjm-16	158	19	studies	study	NOUN
bptjm-16	158	20	in	in	ADP
bptjm-16	158	21	drosophila	drosophila	PROPN
bptjm-16	158	22	,	,	PUNCT
bptjm-16	158	23	in	in	ADP
bptjm-16	158	24	which	which	PRON
bptjm-16	158	25	loss	loss	NOUN
bptjm-16	158	26	of	of	ADP
bptjm-16	158	27	diap1	diap1	NOUN
bptjm-16	158	28	resulted	result	VERB
bptjm-16	158	29	in	in	ADP
bptjm-16	158	30	extensive	extensive	ADJ
bptjm-16	158	31	early	early	ADJ
bptjm-16	158	32	embryonic	embryonic	ADJ
bptjm-16	158	33	cell	cell	NOUN
bptjm-16	158	34	death	death	NOUN
bptjm-16	158	35	and	and	CCONJ
bptjm-16	158	36	a	a	DET
bptjm-16	158	37	corresponding	corresponding	ADJ
bptjm-16	158	38	increase	increase	NOUN
bptjm-16	158	39	in	in	ADP
bptjm-16	158	40	caspase	caspase	PROPN
bptjm-16	158	41	activity82	activity82	PROPN
bptjm-16	158	42	.	.	PUNCT
bptjm-16	159	1	however	however	ADV
bptjm-16	159	2	,	,	PUNCT
bptjm-16	159	3	these	these	DET
bptjm-16	159	4	studies	study	NOUN
bptjm-16	159	5	can	can	AUX
bptjm-16	159	6	not	not	PART
bptjm-16	159	7	be	be	AUX
bptjm-16	159	8	extrapolated	extrapolate	VERB
bptjm-16	159	9	to	to	ADP
bptjm-16	159	10	human	human	ADJ
bptjm-16	159	11	models	model	NOUN
bptjm-16	159	12	due	due	ADJ
bptjm-16	159	13	to	to	ADP
bptjm-16	159	14	obvious	obvious	ADJ
bptjm-16	159	15	anatomical	anatomical	ADJ
bptjm-16	159	16	and	and	CCONJ
bptjm-16	159	17	physiological	physiological	ADJ
bptjm-16	159	18	di	di	NOUN
bptjm-16	159	19	erences	erence	NOUN
bptjm-16	159	20	.	.	PUNCT
bptjm-16	160	1	an	an	DET
bptjm-16	160	2	equivalent	equivalent	ADJ
bptjm-16	160	3	study	study	NOUN
bptjm-16	160	4	in	in	ADP
bptjm-16	160	5	mammals	mammal	NOUN
bptjm-16	160	6	is	be	AUX
bptjm-16	160	7	necessary	necessary	ADJ
bptjm-16	160	8	to	to	PART
bptjm-16	160	9	establish	establish	VERB
bptjm-16	160	10	the	the	DET
bptjm-16	160	11	role	role	NOUN
bptjm-16	160	12	of	of	ADP
bptjm-16	160	13	these	these	DET
bptjm-16	160	14	proteins	protein	NOUN
bptjm-16	160	15	in	in	ADP
bptjm-16	160	16	mammalian	mammalian	ADJ
bptjm-16	160	17	developmental	developmental	ADJ
bptjm-16	160	18	cell	cell	NOUN
bptjm-16	160	19	death	death	NOUN
bptjm-16	160	20	.	.	PUNCT
bptjm-16	161	1	recent	recent	ADJ
bptjm-16	161	2	studies	study	NOUN
bptjm-16	161	3	have	have	AUX
bptjm-16	161	4	greatly	greatly	ADV
bptjm-16	161	5	advanced	advance	VERB
bptjm-16	161	6	our	our	PRON
bptjm-16	161	7	understanding	understanding	NOUN
bptjm-16	161	8	of	of	ADP
bptjm-16	161	9	iaps	iap	NOUN
bptjm-16	161	10	and	and	CCONJ
bptjm-16	161	11	their	their	PRON
bptjm-16	161	12	part	part	NOUN
bptjm-16	161	13	in	in	ADP
bptjm-16	161	14	inhibiting	inhibit	VERB
bptjm-16	161	15	cell	cell	NOUN
bptjm-16	161	16	death	death	NOUN
bptjm-16	161	17	.	.	PUNCT
bptjm-16	162	1	structurally	structurally	ADV
bptjm-16	162	2	,	,	PUNCT
bptjm-16	162	3	it	it	PRON
bptjm-16	162	4	is	be	AUX
bptjm-16	162	5	now	now	ADV
bptjm-16	162	6	evident	evident	ADJ
bptjm-16	162	7	how	how	SCONJ
bptjm-16	162	8	iaps	iap	NOUN
bptjm-16	162	9	interact	interact	VERB
bptjm-16	162	10	with	with	ADP
bptjm-16	162	11	caspases	caspase	NOUN
bptjm-16	162	12	,	,	PUNCT
bptjm-16	162	13	and	and	CCONJ
bptjm-16	162	14	how	how	SCONJ
bptjm-16	162	15	this	this	DET
bptjm-16	162	16	interaction	interaction	NOUN
bptjm-16	162	17	can	can	AUX
bptjm-16	162	18	be	be	AUX
bptjm-16	162	19	regulated	regulate	VERB
bptjm-16	162	20	by	by	ADP
bptjm-16	162	21	iap	iap	PROPN
bptjm-16	162	22	antagonists	antagonist	NOUN
bptjm-16	162	23	such	such	ADJ
bptjm-16	162	24	as	as	ADP
bptjm-16	162	25	diablo	diablo	NOUN
bptjm-16	162	26	.	.	PUNCT
bptjm-16	163	1	though	though	ADV
bptjm-16	163	2	,	,	PUNCT
bptjm-16	163	3	further	further	ADJ
bptjm-16	163	4	research	research	NOUN
bptjm-16	163	5	is	be	AUX
bptjm-16	163	6	still	still	ADV
bptjm-16	163	7	required	require	VERB
bptjm-16	163	8	to	to	ADP
bptjm-16	163	9	de	de	X
bptjm-16	163	10	ne	ne	VERB
bptjm-16	163	11	the	the	DET
bptjm-16	163	12	various	various	ADJ
bptjm-16	163	13	roles	role	NOUN
bptjm-16	163	14	for	for	ADP
bptjm-16	163	15	di	di	NOUN
bptjm-16	163	16	erent	erent	NOUN
bptjm-16	163	17	mammalian	mammalian	PROPN
bptjm-16	163	18	iap	iap	PROPN
bptjm-16	163	19	proteins	protein	NOUN
bptjm-16	163	20	in	in	ADP
bptjm-16	163	21	the	the	DET
bptjm-16	163	22	presence	presence	NOUN
bptjm-16	163	23	of	of	ADP
bptjm-16	163	24	cell	cell	NOUN
bptjm-16	163	25	-	-	PUNCT
bptjm-16	163	26	death	death	NOUN
bptjm-16	163	27	stimuli	stimulus	NOUN
bptjm-16	163	28	.	.	PUNCT
bptjm-16	164	1	indeed	indeed	ADV
bptjm-16	164	2	,	,	PUNCT
bptjm-16	164	3	there	there	PRON
bptjm-16	164	4	could	could	AUX
bptjm-16	164	5	potentially	potentially	ADV
bptjm-16	164	6	be	be	AUX
bptjm-16	164	7	some	some	DET
bptjm-16	164	8	redundancy	redundancy	NOUN
bptjm-16	164	9	between	between	ADP
bptjm-16	164	10	family	family	NOUN
bptjm-16	164	11	members	member	NOUN
bptjm-16	164	12	.	.	PUNCT
bptjm-16	165	1	as	as	ADP
bptjm-16	165	2	a	a	DET
bptjm-16	165	3	result	result	NOUN
bptjm-16	165	4	,	,	PUNCT
bptjm-16	165	5	it	it	PRON
bptjm-16	165	6	is	be	AUX
bptjm-16	165	7	necessary	necessary	ADJ
bptjm-16	165	8	to	to	PART
bptjm-16	165	9	generate	generate	VERB
bptjm-16	165	10	mice	mouse	NOUN
bptjm-16	165	11	de	de	X
bptjm-16	165	12	cient	cient	NOUN
bptjm-16	165	13	for	for	ADP
bptjm-16	165	14	more	more	ADJ
bptjm-16	165	15	than	than	ADP
bptjm-16	165	16	one	one	NUM
bptjm-16	165	17	iap	iap	PROPN
bptjm-16	165	18	,	,	PUNCT
bptjm-16	165	19	to	to	PART
bptjm-16	165	20	establish	establish	VERB
bptjm-16	165	21	the	the	DET
bptjm-16	165	22	role	role	NOUN
bptjm-16	165	23	of	of	ADP
bptjm-16	165	24	iaps	iap	NOUN
bptjm-16	165	25	in	in	ADP
bptjm-16	165	26	mammals	mammal	NOUN
bptjm-16	165	27	.	.	PUNCT
bptjm-16	166	1	so	so	ADV
bptjm-16	166	2	far	far	ADV
bptjm-16	166	3	,	,	PUNCT
bptjm-16	166	4	researchers	researcher	NOUN
bptjm-16	166	5	have	have	AUX
bptjm-16	166	6	only	only	ADV
bptjm-16	166	7	found	find	VERB
bptjm-16	166	8	one	one	NUM
bptjm-16	166	9	mammalian	mammalian	NOUN
bptjm-16	166	10	iap	iap	PROPN
bptjm-16	166	11	antagonist	antagonist	NOUN
bptjm-16	166	12	,	,	PUNCT
bptjm-16	166	13	diablo	diablo	PROPN
bptjm-16	166	14	.	.	PUNCT
bptjm-16	167	1	however	however	ADV
bptjm-16	167	2	,	,	PUNCT
bptjm-16	167	3	considering	consider	VERB
bptjm-16	167	4	that	that	SCONJ
bptjm-16	167	5	there	there	PRON
bptjm-16	167	6	are	be	VERB
bptjm-16	167	7	three	three	NUM
bptjm-16	167	8	such	such	ADJ
bptjm-16	167	9	proteins	protein	NOUN
bptjm-16	167	10	in	in	ADP
bptjm-16	167	11	drosophila	drosophila	NOUN
bptjm-16	167	12	,	,	PUNCT
bptjm-16	167	13	other	other	ADJ
bptjm-16	167	14	mammalian	mammalian	NOUN
bptjm-16	167	15	iap	iap	PROPN
bptjm-16	167	16	antagonists	antagonist	NOUN
bptjm-16	167	17	must	must	AUX
bptjm-16	167	18	certainly	certainly	ADV
bptjm-16	167	19	exist	exist	VERB
bptjm-16	167	20	.	.	PUNCT
bptjm-16	168	1	future	future	ADJ
bptjm-16	168	2	research	research	NOUN
bptjm-16	168	3	investigating	investigate	VERB
bptjm-16	168	4	the	the	DET
bptjm-16	168	5	direct	direct	ADJ
bptjm-16	168	6	interactions	interaction	NOUN
bptjm-16	168	7	of	of	ADP
bptjm-16	168	8	bir	bir	NOUN
bptjm-16	168	9	domains	domain	NOUN
bptjm-16	168	10	from	from	ADP
bptjm-16	168	11	these	these	DET
bptjm-16	168	12	proteins	protein	NOUN
bptjm-16	168	13	with	with	ADP
bptjm-16	168	14	other	other	ADJ
bptjm-16	168	15	cellular	cellular	ADJ
bptjm-16	168	16	proteins	protein	NOUN
bptjm-16	168	17	are	be	AUX
bptjm-16	168	18	likely	likely	ADJ
bptjm-16	168	19	to	to	PART
bptjm-16	168	20	illustrate	illustrate	VERB
bptjm-16	168	21	the	the	DET
bptjm-16	168	22	roles	role	NOUN
bptjm-16	168	23	of	of	ADP
bptjm-16	168	24	iap	iap	PROPN
bptjm-16	168	25	proteins	protein	NOUN
bptjm-16	168	26	in	in	ADP
bptjm-16	168	27	regulating	regulate	VERB
bptjm-16	168	28	cell	cell	NOUN
bptjm-16	168	29	death	death	NOUN
bptjm-16	168	30	.	.	PUNCT
bptjm-16	169	1	conclusion	conclusion	NOUN
bptjm-16	169	2	apoptosis	apoptosis	NOUN
bptjm-16	169	3	and	and	CCONJ
bptjm-16	169	4	necrosis	necrosis	NOUN
bptjm-16	169	5	are	be	AUX
bptjm-16	169	6	two	two	NUM
bptjm-16	169	7	of	of	ADP
bptjm-16	169	8	the	the	DET
bptjm-16	169	9	most	most	ADV
bptjm-16	169	10	known	know	VERB
bptjm-16	169	11	types	type	NOUN
bptjm-16	169	12	of	of	ADP
bptjm-16	169	13	cell	cell	NOUN
bptjm-16	169	14	death	death	NOUN
bptjm-16	169	15	that	that	PRON
bptjm-16	169	16	play	play	VERB
bptjm-16	169	17	an	an	DET
bptjm-16	169	18	essential	essential	ADJ
bptjm-16	169	19	role	role	NOUN
bptjm-16	169	20	in	in	ADP
bptjm-16	169	21	cell	cell	NOUN
bptjm-16	169	22	development	development	NOUN
bptjm-16	169	23	.	.	PUNCT
bptjm-16	170	1	the	the	DET
bptjm-16	170	2	strictly	strictly	ADV
bptjm-16	170	3	distinct	distinct	ADJ
bptjm-16	170	4	berkeley	berkeley	PROPN
bptjm-16	170	5	pharma	pharma	PROPN
bptjm-16	170	6	tech	tech	NOUN
bptjm-16	170	7	journal	journal	NOUN
bptjm-16	170	8	of	of	ADP
bptjm-16	170	9	medicine	medicine	NOUN
bptjm-16	170	10	|	|	ADV
bptjm-16	170	11	107	107	NUM
bptjm-16	170	12	morphological	morphological	ADJ
bptjm-16	170	13	features	feature	NOUN
bptjm-16	170	14	of	of	ADP
bptjm-16	170	15	apoptosis	apoptosis	NOUN
bptjm-16	170	16	include	include	VERB
bptjm-16	170	17	chromosome	chromosome	NOUN
bptjm-16	170	18	condensation	condensation	NOUN
bptjm-16	170	19	,	,	PUNCT
bptjm-16	170	20	nuclear	nuclear	ADJ
bptjm-16	170	21	fragmentation	fragmentation	NOUN
bptjm-16	170	22	,	,	PUNCT
bptjm-16	170	23	and	and	CCONJ
bptjm-16	170	24	membrane	membrane	NOUN
bptjm-16	170	25	blebbing	blebbing	NOUN
bptjm-16	170	26	.	.	PUNCT
bptjm-16	171	1	necrosis	necrosis	NOUN
bptjm-16	171	2	,	,	PUNCT
bptjm-16	171	3	on	on	ADP
bptjm-16	171	4	the	the	DET
bptjm-16	171	5	other	other	ADJ
bptjm-16	171	6	hand	hand	NOUN
bptjm-16	171	7	,	,	PUNCT
bptjm-16	171	8	is	be	AUX
bptjm-16	171	9	characterized	characterize	VERB
bptjm-16	171	10	by	by	ADP
bptjm-16	171	11	the	the	DET
bptjm-16	171	12	expansion	expansion	NOUN
bptjm-16	171	13	of	of	ADP
bptjm-16	171	14	cellular	cellular	ADJ
bptjm-16	171	15	organelles	organelle	NOUN
bptjm-16	171	16	,	,	PUNCT
bptjm-16	171	17	plasma	plasma	NOUN
bptjm-16	171	18	membrane	membrane	NOUN
bptjm-16	171	19	rupture	rupture	NOUN
bptjm-16	171	20	,	,	PUNCT
bptjm-16	171	21	and	and	CCONJ
bptjm-16	171	22	in	in	ADP
bptjm-16	171	23	ammatory	ammatory	NOUN
bptjm-16	171	24	responses	response	NOUN
bptjm-16	171	25	resulting	result	VERB
bptjm-16	171	26	from	from	ADP
bptjm-16	171	27	the	the	DET
bptjm-16	171	28	release	release	NOUN
bptjm-16	171	29	of	of	ADP
bptjm-16	171	30	the	the	DET
bptjm-16	171	31	intracellular	intracellular	ADJ
bptjm-16	171	32	contents	content	NOUN
bptjm-16	171	33	.	.	PUNCT
bptjm-16	172	1	the	the	DET
bptjm-16	172	2	apoptotic	apoptotic	ADJ
bptjm-16	172	3	pathway	pathway	NOUN
bptjm-16	172	4	—	—	PUNCT
bptjm-16	172	5	an	an	DET
bptjm-16	172	6	energy	energy	NOUN
bptjm-16	172	7	-	-	PUNCT
bptjm-16	172	8	dependent	dependent	ADJ
bptjm-16	172	9	cascade	cascade	NOUN
bptjm-16	172	10	of	of	ADP
bptjm-16	172	11	molecular	molecular	ADJ
bptjm-16	172	12	events	event	NOUN
bptjm-16	172	13	—	—	PUNCT
bptjm-16	172	14	is	be	AUX
bptjm-16	172	15	initiated	initiate	VERB
bptjm-16	172	16	by	by	ADP
bptjm-16	172	17	3	3	NUM
bptjm-16	172	18	primary	primary	ADJ
bptjm-16	172	19	pathways	pathway	NOUN
bptjm-16	172	20	:	:	PUNCT
bptjm-16	172	21	the	the	DET
bptjm-16	172	22	extrinsic	extrinsic	ADJ
bptjm-16	172	23	(	(	PUNCT
bptjm-16	172	24	cell	cell	NOUN
bptjm-16	172	25	-	-	PUNCT
bptjm-16	172	26	death	death	NOUN
bptjm-16	172	27	)	)	PUNCT
bptjm-16	172	28	receptor	receptor	NOUN
bptjm-16	172	29	pathway	pathway	NOUN
bptjm-16	172	30	,	,	PUNCT
bptjm-16	172	31	the	the	DET
bptjm-16	172	32	intrinsic	intrinsic	ADJ
bptjm-16	172	33	(	(	PUNCT
bptjm-16	172	34	mitochondrial	mitochondrial	ADJ
bptjm-16	172	35	)	)	PUNCT
bptjm-16	172	36	pathway	pathway	NOUN
bptjm-16	172	37	,	,	PUNCT
bptjm-16	172	38	and	and	CCONJ
bptjm-16	172	39	the	the	DET
bptjm-16	172	40	stress	stress	NOUN
bptjm-16	172	41	-	-	PUNCT
bptjm-16	172	42	induced	induce	VERB
bptjm-16	172	43	pathway	pathway	NOUN
bptjm-16	172	44	in	in	ADP
bptjm-16	172	45	the	the	DET
bptjm-16	172	46	endoplasmic	endoplasmic	ADJ
bptjm-16	172	47	reticulum	reticulum	NOUN
bptjm-16	172	48	.	.	PUNCT
bptjm-16	173	1	although	although	SCONJ
bptjm-16	173	2	these	these	DET
bptjm-16	173	3	pathways	pathway	NOUN
bptjm-16	173	4	utilize	utilize	VERB
bptjm-16	173	5	di	di	NOUN
bptjm-16	173	6	erent	erent	NOUN
bptjm-16	173	7	initiator	initiator	NOUN
bptjm-16	173	8	caspases	caspase	NOUN
bptjm-16	173	9	(	(	PUNCT
bptjm-16	173	10	caspase-8	caspase-8	PROPN
bptjm-16	173	11	,	,	PUNCT
bptjm-16	173	12	caspase-9	caspase-9	PROPN
bptjm-16	173	13	,	,	PUNCT
bptjm-16	173	14	and	and	CCONJ
bptjm-16	173	15	caspase-10	caspase-10	PROPN
bptjm-16	173	16	,	,	PUNCT
bptjm-16	173	17	respectively	respectively	ADV
bptjm-16	173	18	)	)	PUNCT
bptjm-16	173	19	,	,	PUNCT
bptjm-16	173	20	they	they	PRON
bptjm-16	173	21	activate	activate	VERB
bptjm-16	173	22	the	the	DET
bptjm-16	173	23	same	same	ADJ
bptjm-16	173	24	downstream	downstream	ADJ
bptjm-16	173	25	mediator	mediator	NOUN
bptjm-16	173	26	molecule	molecule	NOUN
bptjm-16	173	27	,	,	PUNCT
bptjm-16	173	28	caspase-3	caspase-3	NUM
bptjm-16	173	29	.	.	PUNCT
bptjm-16	174	1	meanwhile	meanwhile	ADV
bptjm-16	174	2	,	,	PUNCT
bptjm-16	174	3	necrosis	necrosis	NOUN
bptjm-16	174	4	is	be	AUX
bptjm-16	174	5	classi	classi	ADJ
bptjm-16	174	6	ed	ed	NOUN
bptjm-16	174	7	as	as	ADP
bptjm-16	174	8	accidental	accidental	ADJ
bptjm-16	174	9	cell	cell	NOUN
bptjm-16	174	10	death	death	NOUN
bptjm-16	174	11	caused	cause	VERB
bptjm-16	174	12	by	by	ADP
bptjm-16	174	13	internal	internal	ADJ
bptjm-16	174	14	or	or	CCONJ
bptjm-16	174	15	external	external	ADJ
bptjm-16	174	16	stresses	stress	NOUN
bptjm-16	174	17	.	.	PUNCT
bptjm-16	175	1	in	in	ADP
bptjm-16	175	2	necrosis	necrosis	NOUN
bptjm-16	175	3	,	,	PUNCT
bptjm-16	175	4	the	the	DET
bptjm-16	175	5	disruption	disruption	NOUN
bptjm-16	175	6	of	of	ADP
bptjm-16	175	7	membrane	membrane	NOUN
bptjm-16	175	8	homeostasis	homeostasis	NOUN
bptjm-16	175	9	results	result	NOUN
bptjm-16	175	10	in	in	ADP
bptjm-16	175	11	water	water	NOUN
bptjm-16	175	12	imbalance	imbalance	NOUN
bptjm-16	175	13	between	between	ADP
bptjm-16	175	14	the	the	DET
bptjm-16	175	15	extracellular	extracellular	ADJ
bptjm-16	175	16	and	and	CCONJ
bptjm-16	175	17	intracellular	intracellular	ADJ
bptjm-16	175	18	environments	environment	NOUN
bptjm-16	175	19	.	.	PUNCT
bptjm-16	176	1	whether	whether	SCONJ
bptjm-16	176	2	cells	cell	NOUN
bptjm-16	176	3	undergo	undergo	VERB
bptjm-16	176	4	apoptosis	apoptosis	NOUN
bptjm-16	176	5	or	or	CCONJ
bptjm-16	176	6	necrosis	necrosis	NOUN
bptjm-16	176	7	depends	depend	VERB
bptjm-16	176	8	on	on	ADP
bptjm-16	176	9	the	the	DET
bptjm-16	176	10	availability	availability	NOUN
bptjm-16	176	11	of	of	ADP
bptjm-16	176	12	caspases	caspase	NOUN
bptjm-16	176	13	,	,	PUNCT
bptjm-16	176	14	and	and	CCONJ
bptjm-16	176	15	intracellular	intracellular	ADJ
bptjm-16	176	16	atp	atp	NOUN
bptjm-16	176	17	that	that	PRON
bptjm-16	176	18	determine	determine	VERB
bptjm-16	176	19	the	the	DET
bptjm-16	176	20	cell	cell	NOUN
bptjm-16	176	21	-	-	PUNCT
bptjm-16	176	22	death	death	NOUN
bptjm-16	176	23	signal	signal	NOUN
bptjm-16	176	24	,	,	PUNCT
bptjm-16	176	25	signaling	signal	VERB
bptjm-16	176	26	duration	duration	NOUN
bptjm-16	176	27	,	,	PUNCT
bptjm-16	176	28	tissue	tissue	NOUN
bptjm-16	176	29	type	type	NOUN
bptjm-16	176	30	,	,	PUNCT
bptjm-16	176	31	and	and	CCONJ
bptjm-16	176	32	the	the	DET
bptjm-16	176	33	developmental	developmental	ADJ
bptjm-16	176	34	stage	stage	NOUN
bptjm-16	176	35	of	of	ADP
bptjm-16	176	36	the	the	DET
bptjm-16	176	37	tissue	tissue	NOUN
bptjm-16	176	38	.	.	PUNCT
bptjm-16	177	1	in	in	ADP
bptjm-16	177	2	summary	summary	NOUN
bptjm-16	177	3	,	,	PUNCT
bptjm-16	177	4	necrosis	necrosis	NOUN
bptjm-16	177	5	is	be	AUX
bptjm-16	177	6	an	an	DET
bptjm-16	177	7	unregulated	unregulated	ADJ
bptjm-16	177	8	and	and	CCONJ
bptjm-16	177	9	passive	passive	ADJ
bptjm-16	177	10	process	process	NOUN
bptjm-16	177	11	that	that	PRON
bptjm-16	177	12	usually	usually	ADV
bptjm-16	177	13	a	a	DET
bptjm-16	177	14	ects	ect	VERB
bptjm-16	177	15	a	a	DET
bptjm-16	177	16	larger	large	ADJ
bptjm-16	177	17	region	region	NOUN
bptjm-16	177	18	of	of	ADP
bptjm-16	177	19	cells	cell	NOUN
bptjm-16	177	20	,	,	PUNCT
bptjm-16	177	21	whereas	whereas	SCONJ
bptjm-16	177	22	apoptosis	apoptosis	NOUN
bptjm-16	177	23	is	be	AUX
bptjm-16	177	24	a	a	DET
bptjm-16	177	25	contained	contain	VERB
bptjm-16	177	26	and	and	CCONJ
bptjm-16	177	27	energy	energy	NOUN
bptjm-16	177	28	-	-	PUNCT
bptjm-16	177	29	dependent	dependent	ADJ
bptjm-16	177	30	process	process	NOUN
bptjm-16	177	31	that	that	PRON
bptjm-16	177	32	a	a	DET
bptjm-16	177	33	ects	ect	VERB
bptjm-16	177	34	an	an	DET
bptjm-16	177	35	individual	individual	ADJ
bptjm-16	177	36	or	or	CCONJ
bptjm-16	177	37	smaller	small	ADJ
bptjm-16	177	38	clusters	cluster	NOUN
bptjm-16	177	39	of	of	ADP
bptjm-16	177	40	cells	cell	NOUN
bptjm-16	177	41	.	.	PUNCT
bptjm-16	178	1	studies	study	NOUN
bptjm-16	178	2	have	have	AUX
bptjm-16	178	3	demonstrated	demonstrate	VERB
bptjm-16	178	4	that	that	SCONJ
bptjm-16	178	5	the	the	DET
bptjm-16	178	6	repression	repression	NOUN
bptjm-16	178	7	of	of	ADP
bptjm-16	178	8	apoptosis	apoptosis	NOUN
bptjm-16	178	9	,	,	PUNCT
bptjm-16	178	10	or	or	CCONJ
bptjm-16	178	11	the	the	DET
bptjm-16	178	12	inhibition	inhibition	NOUN
bptjm-16	178	13	of	of	ADP
bptjm-16	178	14	programmed	programmed	ADJ
bptjm-16	178	15	cell	cell	NOUN
bptjm-16	178	16	death	death	NOUN
bptjm-16	178	17	,	,	PUNCT
bptjm-16	178	18	increases	increase	VERB
bptjm-16	178	19	the	the	DET
bptjm-16	178	20	possibility	possibility	NOUN
bptjm-16	178	21	of	of	ADP
bptjm-16	178	22	malignancy	malignancy	NOUN
bptjm-16	178	23	.	.	PUNCT
bptjm-16	179	1	in	in	ADP
bptjm-16	179	2	contrast	contrast	NOUN
bptjm-16	179	3	,	,	PUNCT
bptjm-16	179	4	uncontrolled	uncontrolled	ADJ
bptjm-16	179	5	apoptosis	apoptosis	NOUN
bptjm-16	179	6	has	have	AUX
bptjm-16	179	7	been	be	AUX
bptjm-16	179	8	found	find	VERB
bptjm-16	179	9	to	to	PART
bptjm-16	179	10	be	be	AUX
bptjm-16	179	11	associated	associate	VERB
bptjm-16	179	12	with	with	ADP
bptjm-16	179	13	degenerative	degenerative	ADJ
bptjm-16	179	14	diseases	disease	NOUN
bptjm-16	179	15	such	such	ADJ
bptjm-16	179	16	as	as	ADP
bptjm-16	179	17	acquired	acquire	VERB
bptjm-16	179	18	immunode	immunode	ADJ
bptjm-16	179	19	ciency	ciency	NOUN
bptjm-16	179	20	syndrome	syndrome	NOUN
bptjm-16	179	21	(	(	PUNCT
bptjm-16	179	22	aids	aids	PROPN
bptjm-16	179	23	)	)	PUNCT
bptjm-16	179	24	,	,	PUNCT
bptjm-16	179	25	cancer	cancer	NOUN
bptjm-16	179	26	,	,	PUNCT
bptjm-16	179	27	parkinson	parkinson	NOUN
bptjm-16	179	28	's	's	PART
bptjm-16	179	29	disease	disease	NOUN
bptjm-16	179	30	,	,	PUNCT
bptjm-16	179	31	and	and	CCONJ
bptjm-16	179	32	alzheimer	alzheimer	PROPN
bptjm-16	179	33	's	's	PART
bptjm-16	179	34	disease	disease	NOUN
bptjm-16	179	35	.	.	PUNCT
bptjm-16	180	1	recently	recently	ADV
bptjm-16	180	2	,	,	PUNCT
bptjm-16	180	3	a	a	DET
bptjm-16	180	4	programmed	program	VERB
bptjm-16	180	5	form	form	NOUN
bptjm-16	180	6	of	of	ADP
bptjm-16	180	7	necrosis	necrosis	NOUN
bptjm-16	180	8	,	,	PUNCT
bptjm-16	180	9	necroptosis	necroptosis	NOUN
bptjm-16	180	10	,	,	PUNCT
bptjm-16	180	11	has	have	AUX
bptjm-16	180	12	been	be	AUX
bptjm-16	180	13	proposed	propose	VERB
bptjm-16	180	14	as	as	ADP
bptjm-16	180	15	an	an	DET
bptjm-16	180	16	important	important	ADJ
bptjm-16	180	17	pathway	pathway	NOUN
bptjm-16	180	18	involved	involve	VERB
bptjm-16	180	19	in	in	ADP
bptjm-16	180	20	many	many	ADJ
bptjm-16	180	21	diseases	disease	NOUN
bptjm-16	180	22	.	.	PUNCT
bptjm-16	181	1	the	the	DET
bptjm-16	181	2	primary	primary	ADJ
bptjm-16	181	3	function	function	NOUN
bptjm-16	181	4	of	of	ADP
bptjm-16	181	5	necroptosis	necroptosis	NOUN
bptjm-16	181	6	was	be	AUX
bptjm-16	181	7	believed	believe	VERB
bptjm-16	181	8	to	to	PART
bptjm-16	181	9	be	be	AUX
bptjm-16	181	10	infection	infection	NOUN
bptjm-16	181	11	control	control	NOUN
bptjm-16	181	12	and	and	CCONJ
bptjm-16	181	13	protection	protection	NOUN
bptjm-16	181	14	against	against	ADP
bptjm-16	181	15	virus	virus	NOUN
bptjm-16	181	16	-	-	PUNCT
bptjm-16	181	17	induced	induce	VERB
bptjm-16	181	18	apoptosis	apoptosis	NOUN
bptjm-16	181	19	.	.	PUNCT
bptjm-16	182	1	however	however	ADV
bptjm-16	182	2	,	,	PUNCT
bptjm-16	182	3	like	like	ADP
bptjm-16	182	4	apoptosis	apoptosis	NOUN
bptjm-16	182	5	,	,	PUNCT
bptjm-16	182	6	necroptosis	necroptosis	NOUN
bptjm-16	182	7	has	have	AUX
bptjm-16	182	8	also	also	ADV
bptjm-16	182	9	been	be	AUX
bptjm-16	182	10	found	find	VERB
bptjm-16	182	11	to	to	PART
bptjm-16	182	12	be	be	AUX
bptjm-16	182	13	associated	associate	VERB
bptjm-16	182	14	with	with	ADP
bptjm-16	182	15	certain	certain	ADJ
bptjm-16	182	16	neurodegenerative	neurodegenerative	ADJ
bptjm-16	182	17	diseases	disease	NOUN
bptjm-16	182	18	such	such	ADJ
bptjm-16	182	19	as	as	ADP
bptjm-16	182	20	alzheimer	alzheimer	PROPN
bptjm-16	182	21	’s	’s	PART
bptjm-16	182	22	disease	disease	NOUN
bptjm-16	182	23	,	,	PUNCT
bptjm-16	182	24	multiple	multiple	ADJ
bptjm-16	182	25	sclerosis	sclerosis	NOUN
bptjm-16	182	26	,	,	PUNCT
bptjm-16	182	27	and	and	CCONJ
bptjm-16	182	28	amyotrophic	amyotrophic	ADJ
bptjm-16	182	29	lateral	lateral	ADJ
bptjm-16	182	30	sclerosis	sclerosis	NOUN
bptjm-16	182	31	.	.	PUNCT
bptjm-16	183	1	due	due	ADP
bptjm-16	183	2	to	to	ADP
bptjm-16	183	3	the	the	DET
bptjm-16	183	4	emerging	emerge	VERB
bptjm-16	183	5	crosstalk	crosstalk	NOUN
bptjm-16	183	6	between	between	ADP
bptjm-16	183	7	the	the	DET
bptjm-16	183	8	di	di	NOUN
bptjm-16	183	9	ering	ere	VERB
bptjm-16	183	10	forms	form	NOUN
bptjm-16	183	11	of	of	ADP
bptjm-16	183	12	cell	cell	NOUN
bptjm-16	183	13	death	death	NOUN
bptjm-16	183	14	,	,	PUNCT
bptjm-16	183	15	these	these	DET
bptjm-16	183	16	processes	process	NOUN
bptjm-16	183	17	are	be	AUX
bptjm-16	183	18	now	now	ADV
bptjm-16	183	19	considered	consider	VERB
bptjm-16	183	20	interconnected	interconnected	ADJ
bptjm-16	183	21	.	.	PUNCT
bptjm-16	184	1	thus	thus	ADV
bptjm-16	184	2	,	,	PUNCT
bptjm-16	184	3	di	di	X
bptjm-16	184	4	erentiating	erentiate	VERB
bptjm-16	184	5	between	between	ADP
bptjm-16	184	6	apoptotic	apoptotic	ADJ
bptjm-16	184	7	,	,	PUNCT
bptjm-16	184	8	necrotic	necrotic	ADJ
bptjm-16	184	9	,	,	PUNCT
bptjm-16	184	10	and	and	CCONJ
bptjm-16	184	11	necroptotic	necroptotic	ADJ
bptjm-16	184	12	cellular	cellular	ADJ
bptjm-16	184	13	mechanisms	mechanism	NOUN
bptjm-16	184	14	is	be	AUX
bptjm-16	184	15	critical	critical	ADJ
bptjm-16	184	16	to	to	ADP
bptjm-16	184	17	understanding	understand	VERB
bptjm-16	184	18	disease	disease	NOUN
bptjm-16	184	19	progression	progression	NOUN
bptjm-16	184	20	.	.	PUNCT
bptjm-16	185	1	the	the	DET
bptjm-16	185	2	recent	recent	ADJ
bptjm-16	185	3	discovery	discovery	NOUN
bptjm-16	185	4	of	of	ADP
bptjm-16	185	5	a	a	DET
bptjm-16	185	6	family	family	NOUN
bptjm-16	185	7	of	of	ADP
bptjm-16	185	8	genetically	genetically	ADV
bptjm-16	185	9	conserved	conserve	VERB
bptjm-16	185	10	proteins	protein	NOUN
bptjm-16	185	11	,	,	PUNCT
bptjm-16	185	12	known	know	VERB
bptjm-16	185	13	as	as	ADP
bptjm-16	185	14	iaps	iap	NOUN
bptjm-16	185	15	,	,	PUNCT
bptjm-16	185	16	provided	provide	VERB
bptjm-16	185	17	new	new	ADJ
bptjm-16	185	18	insights	insight	NOUN
bptjm-16	185	19	into	into	ADP
bptjm-16	185	20	the	the	DET
bptjm-16	185	21	molecules	molecule	NOUN
bptjm-16	185	22	that	that	PRON
bptjm-16	185	23	play	play	VERB
bptjm-16	185	24	a	a	DET
bptjm-16	185	25	critical	critical	ADJ
bptjm-16	185	26	role	role	NOUN
bptjm-16	185	27	in	in	ADP
bptjm-16	185	28	mediating	mediate	VERB
bptjm-16	185	29	these	these	DET
bptjm-16	185	30	cell	cell	NOUN
bptjm-16	185	31	death	death	NOUN
bptjm-16	185	32	pathways	pathway	NOUN
bptjm-16	185	33	.	.	PUNCT
bptjm-16	186	1	inhibitors	inhibitor	NOUN
bptjm-16	186	2	of	of	ADP
bptjm-16	186	3	apoptosis	apoptosis	NOUN
bptjm-16	186	4	proteins	protein	NOUN
bptjm-16	186	5	(	(	PUNCT
bptjm-16	186	6	iap	iap	PROPN
bptjm-16	186	7	)	)	PUNCT
bptjm-16	186	8	are	be	AUX
bptjm-16	186	9	a	a	DET
bptjm-16	186	10	type	type	NOUN
bptjm-16	186	11	of	of	ADP
bptjm-16	186	12	berkeley	berkeley	PROPN
bptjm-16	186	13	pharma	pharma	PROPN
bptjm-16	186	14	tech	tech	NOUN
bptjm-16	186	15	journal	journal	NOUN
bptjm-16	186	16	of	of	ADP
bptjm-16	186	17	medicine	medicine	NOUN
bptjm-16	186	18	|	|	ADV
bptjm-16	186	19	108	108	NUM
bptjm-16	186	20	antiapoptotic	antiapoptotic	ADJ
bptjm-16	186	21	protein	protein	NOUN
bptjm-16	186	22	involved	involve	VERB
bptjm-16	186	23	in	in	ADP
bptjm-16	186	24	both	both	PRON
bptjm-16	186	25	,	,	PUNCT
bptjm-16	186	26	the	the	DET
bptjm-16	186	27	intrinsic	intrinsic	ADJ
bptjm-16	186	28	and	and	CCONJ
bptjm-16	186	29	extrinsic	extrinsic	ADJ
bptjm-16	186	30	apoptotic	apoptotic	ADJ
bptjm-16	186	31	pathways	pathway	NOUN
bptjm-16	186	32	.	.	PUNCT
bptjm-16	187	1	cellular	cellular	ADJ
bptjm-16	187	2	iap1	iap1	NOUN
bptjm-16	187	3	and	and	CCONJ
bptjm-16	187	4	2	2	NUM
bptjm-16	187	5	(	(	PUNCT
bptjm-16	187	6	ciap1	ciap1	NOUN
bptjm-16	187	7	and	and	CCONJ
bptjm-16	187	8	ciap2	ciap2	NOUN
bptjm-16	187	9	)	)	PUNCT
bptjm-16	187	10	in	in	ADP
bptjm-16	187	11	particular	particular	ADJ
bptjm-16	187	12	,	,	PUNCT
bptjm-16	187	13	are	be	AUX
bptjm-16	187	14	the	the	DET
bptjm-16	187	15	key	key	ADJ
bptjm-16	187	16	molecules	molecule	NOUN
bptjm-16	187	17	of	of	ADP
bptjm-16	187	18	the	the	DET
bptjm-16	187	19	tumor	tumor	NOUN
bptjm-16	187	20	necrosis	necrosis	NOUN
bptjm-16	187	21	factor	factor	NOUN
bptjm-16	187	22	α	α	PROPN
bptjm-16	187	23	(	(	PUNCT
bptjm-16	187	24	tnfα	tnfα	NOUN
bptjm-16	187	25	)	)	PUNCT
bptjm-16	187	26	signaling	signal	VERB
bptjm-16	187	27	pathway	pathway	NOUN
bptjm-16	187	28	,	,	PUNCT
bptjm-16	187	29	which	which	PRON
bptjm-16	187	30	activates	activate	VERB
bptjm-16	187	31	adaptor	adaptor	NOUN
bptjm-16	187	32	proteins	protein	NOUN
bptjm-16	187	33	such	such	ADJ
bptjm-16	187	34	as	as	ADP
bptjm-16	187	35	tnf	tnf	PROPN
bptjm-16	187	36	receptor	receptor	NOUN
bptjm-16	187	37	-	-	PUNCT
bptjm-16	187	38	associated	associate	VERB
bptjm-16	187	39	factor	factor	NOUN
bptjm-16	187	40	(	(	PUNCT
bptjm-16	187	41	traf	traf	PROPN
bptjm-16	187	42	)	)	PUNCT
bptjm-16	187	43	,	,	PUNCT
bptjm-16	187	44	tnfr	tnfr	NOUN
bptjm-16	187	45	-	-	PUNCT
bptjm-16	187	46	associated	associate	VERB
bptjm-16	187	47	death	death	NOUN
bptjm-16	187	48	domain	domain	NOUN
bptjm-16	187	49	protein	protein	NOUN
bptjm-16	187	50	(	(	PUNCT
bptjm-16	187	51	tradd	tradd	NOUN
bptjm-16	187	52	)	)	PUNCT
bptjm-16	187	53	,	,	PUNCT
bptjm-16	187	54	receptor	receptor	NOUN
bptjm-16	187	55	-	-	PUNCT
bptjm-16	187	56	interacting	interact	VERB
bptjm-16	187	57	serine	serine	NOUN
bptjm-16	187	58	/	/	SYM
bptjm-16	187	59	threonine	threonine	ADJ
bptjm-16	187	60	-	-	PUNCT
bptjm-16	187	61	protein	protein	NOUN
bptjm-16	187	62	kinase	kinase	NOUN
bptjm-16	187	63	1	1	NUM
bptjm-16	187	64	(	(	PUNCT
bptjm-16	187	65	ripk1	ripk1	NOUN
bptjm-16	187	66	)	)	PUNCT
bptjm-16	187	67	,	,	PUNCT
bptjm-16	187	68	and	and	CCONJ
bptjm-16	187	69	linear	linear	ADJ
bptjm-16	187	70	ubiquitin	ubiquitin	NOUN
bptjm-16	187	71	chain	chain	NOUN
bptjm-16	187	72	assembly	assembly	NOUN
bptjm-16	187	73	complex	complex	NOUN
bptjm-16	187	74	(	(	PUNCT
bptjm-16	187	75	lubac	lubac	NOUN
bptjm-16	187	76	)	)	PUNCT
bptjm-16	187	77	to	to	PART
bptjm-16	187	78	induce	induce	VERB
bptjm-16	187	79	the	the	DET
bptjm-16	187	80	nf	nf	ADJ
bptjm-16	187	81	-	-	PUNCT
bptjm-16	187	82	κb	κb	NOUN
bptjm-16	187	83	signaling	signal	VERB
bptjm-16	187	84	pathway	pathway	NOUN
bptjm-16	187	85	and	and	CCONJ
bptjm-16	187	86	promote	promote	VERB
bptjm-16	187	87	cell	cell	NOUN
bptjm-16	187	88	survival	survival	NOUN
bptjm-16	187	89	.	.	PUNCT
bptjm-16	188	1	in	in	ADP
bptjm-16	188	2	short	short	ADJ
bptjm-16	188	3	,	,	PUNCT
bptjm-16	188	4	the	the	DET
bptjm-16	188	5	iaps	iap	NOUN
bptjm-16	188	6	prevent	prevent	VERB
bptjm-16	188	7	apoptosis	apoptosis	NOUN
bptjm-16	188	8	by	by	ADP
bptjm-16	188	9	inhibiting	inhibit	VERB
bptjm-16	188	10	the	the	DET
bptjm-16	188	11	normal	normal	ADJ
bptjm-16	188	12	functions	function	NOUN
bptjm-16	188	13	of	of	ADP
bptjm-16	188	14	downstream	downstream	ADJ
bptjm-16	188	15	caspases	caspase	NOUN
bptjm-16	188	16	,	,	PUNCT
bptjm-16	188	17	including	include	VERB
bptjm-16	188	18	caspase	caspase	PROPN
bptjm-16	188	19	8	8	NUM
bptjm-16	188	20	,	,	PUNCT
bptjm-16	188	21	caspase	caspase	NOUN
bptjm-16	188	22	9	9	NUM
bptjm-16	188	23	,	,	PUNCT
bptjm-16	188	24	and	and	CCONJ
bptjm-16	188	25	caspase	caspase	PROPN
bptjm-16	188	26	3	3	NUM
bptjm-16	188	27	.	.	PUNCT
bptjm-16	189	1	the	the	DET
bptjm-16	189	2	impaired	impair	VERB
bptjm-16	189	3	function	function	NOUN
bptjm-16	189	4	of	of	ADP
bptjm-16	189	5	iap	iap	PROPN
bptjm-16	189	6	could	could	AUX
bptjm-16	189	7	instruct	instruct	VERB
bptjm-16	189	8	the	the	DET
bptjm-16	189	9	cells	cell	NOUN
bptjm-16	189	10	to	to	PART
bptjm-16	189	11	undergo	undergo	VERB
bptjm-16	189	12	necroptosis	necroptosis	NOUN
bptjm-16	189	13	or	or	CCONJ
bptjm-16	189	14	apoptosis	apoptosis	NOUN
bptjm-16	189	15	instead	instead	ADV
bptjm-16	189	16	of	of	ADP
bptjm-16	189	17	the	the	DET
bptjm-16	189	18	nf	nf	ADJ
bptjm-16	189	19	-	-	PUNCT
bptjm-16	189	20	κb	κb	PROPN
bptjm-16	189	21	cell	cell	NOUN
bptjm-16	189	22	survival	survival	NOUN
bptjm-16	189	23	pathway	pathway	NOUN
bptjm-16	189	24	.	.	PUNCT
bptjm-16	190	1	from	from	ADP
bptjm-16	190	2	this	this	DET
bptjm-16	190	3	step	step	NOUN
bptjm-16	190	4	of	of	ADP
bptjm-16	190	5	the	the	DET
bptjm-16	190	6	cell	cell	NOUN
bptjm-16	190	7	death	death	NOUN
bptjm-16	190	8	process	process	NOUN
bptjm-16	190	9	,	,	PUNCT
bptjm-16	190	10	autoactivation	autoactivation	NOUN
bptjm-16	190	11	of	of	ADP
bptjm-16	190	12	caspase	caspase	PROPN
bptjm-16	190	13	8	8	NUM
bptjm-16	190	14	would	would	AUX
bptjm-16	190	15	result	result	VERB
bptjm-16	190	16	in	in	ADP
bptjm-16	190	17	apoptosis	apoptosis	NOUN
bptjm-16	190	18	whereas	whereas	SCONJ
bptjm-16	190	19	the	the	DET
bptjm-16	190	20	absence	absence	NOUN
bptjm-16	190	21	of	of	ADP
bptjm-16	190	22	caspase-8	caspase-8	NOUN
bptjm-16	190	23	autoactivation	autoactivation	NOUN
bptjm-16	190	24	would	would	AUX
bptjm-16	190	25	result	result	VERB
bptjm-16	190	26	in	in	ADP
bptjm-16	190	27	necroptosis	necroptosis	NOUN
bptjm-16	190	28	.	.	PUNCT
bptjm-16	191	1	studies	study	NOUN
bptjm-16	191	2	have	have	AUX
bptjm-16	191	3	demonstrated	demonstrate	VERB
bptjm-16	191	4	how	how	SCONJ
bptjm-16	191	5	the	the	DET
bptjm-16	191	6	iaps	iap	NOUN
bptjm-16	191	7	inhibit	inhibit	VERB
bptjm-16	191	8	programmed	program	VERB
bptjm-16	191	9	cell	cell	NOUN
bptjm-16	191	10	death	death	NOUN
bptjm-16	191	11	.	.	PUNCT
bptjm-16	192	1	however	however	ADV
bptjm-16	192	2	,	,	PUNCT
bptjm-16	192	3	further	further	ADJ
bptjm-16	192	4	investigation	investigation	NOUN
bptjm-16	192	5	is	be	AUX
bptjm-16	192	6	necessary	necessary	ADJ
bptjm-16	192	7	to	to	PART
bptjm-16	192	8	clarify	clarify	VERB
bptjm-16	192	9	the	the	DET
bptjm-16	192	10	roles	role	NOUN
bptjm-16	192	11	of	of	ADP
bptjm-16	192	12	di	di	NOUN
bptjm-16	192	13	erent	erent	NOUN
bptjm-16	192	14	mammalian	mammalian	PROPN
bptjm-16	192	15	iap	iap	PROPN
bptjm-16	192	16	proteins	protein	NOUN
bptjm-16	192	17	in	in	ADP
bptjm-16	192	18	the	the	DET
bptjm-16	192	19	presence	presence	NOUN
bptjm-16	192	20	of	of	ADP
bptjm-16	192	21	various	various	ADJ
bptjm-16	192	22	cell	cell	NOUN
bptjm-16	192	23	-	-	PUNCT
bptjm-16	192	24	death	death	NOUN
bptjm-16	192	25	stimuli	stimulus	NOUN
bptjm-16	192	26	.	.	PUNCT
bptjm-16	193	1	considering	consider	VERB
bptjm-16	193	2	their	their	PRON
bptjm-16	193	3	newfound	newfound	NOUN
bptjm-16	193	4	functions	function	NOUN
bptjm-16	193	5	,	,	PUNCT
bptjm-16	193	6	continued	continue	VERB
bptjm-16	193	7	research	research	NOUN
bptjm-16	193	8	into	into	ADP
bptjm-16	193	9	the	the	DET
bptjm-16	193	10	characteristics	characteristic	NOUN
bptjm-16	193	11	and	and	CCONJ
bptjm-16	193	12	mechanisms	mechanism	NOUN
bptjm-16	193	13	of	of	ADP
bptjm-16	193	14	iap	iap	PROPN
bptjm-16	193	15	molecules	molecule	NOUN
bptjm-16	193	16	will	will	AUX
bptjm-16	193	17	likely	likely	ADV
bptjm-16	193	18	prove	prove	VERB
bptjm-16	193	19	an	an	DET
bptjm-16	193	20	e	e	NOUN
bptjm-16	193	21	ective	ective	ADJ
bptjm-16	193	22	and	and	CCONJ
bptjm-16	193	23	viable	viable	ADJ
bptjm-16	193	24	approach	approach	NOUN
bptjm-16	193	25	to	to	ADP
bptjm-16	193	26	diagnosing	diagnose	VERB
bptjm-16	193	27	or	or	CCONJ
bptjm-16	193	28	treating	treat	VERB
bptjm-16	193	29	several	several	ADJ
bptjm-16	193	30	elusive	elusive	ADJ
bptjm-16	193	31	diseases	disease	NOUN
bptjm-16	193	32	.	.	PUNCT
bptjm-16	194	1	berkeley	berkeley	PROPN
bptjm-16	194	2	pharma	pharma	PROPN
bptjm-16	194	3	tech	tech	PROPN
bptjm-16	194	4	journal	journal	NOUN
bptjm-16	194	5	of	of	ADP
bptjm-16	194	6	medicine	medicine	NOUN
bptjm-16	194	7	|	|	ADV
bptjm-16	194	8	109	109	NUM
bptjm-16	194	9	references	reference	NOUN
bptjm-16	194	10	1	1	NUM
bptjm-16	194	11	.	.	PUNCT
bptjm-16	195	1	elmore	elmore	NOUN
bptjm-16	195	2	s.	s.	PROPN
bptjm-16	195	3	apoptosis	apoptosis	PROPN
bptjm-16	195	4	:	:	PUNCT
bptjm-16	195	5	a	a	DET
bptjm-16	195	6	review	review	NOUN
bptjm-16	195	7	of	of	ADP
bptjm-16	195	8	programmed	program	VERB
bptjm-16	195	9	cell	cell	NOUN
bptjm-16	195	10	death	death	NOUN
bptjm-16	195	11	.	.	PUNCT
bptjm-16	196	1	toxicologic	toxicologic	ADJ
bptjm-16	196	2	pathology	pathology	NOUN
bptjm-16	196	3	.	.	PUNCT
bptjm-16	197	1	2007	2007	NUM
bptjm-16	197	2	jun	jun	PROPN
bptjm-16	197	3	;	;	PUNCT
bptjm-16	197	4	35(4):495	35(4):495	NUM
bptjm-16	197	5	-	-	SYM
bptjm-16	197	6	516	516	NUM
bptjm-16	197	7	.	.	PUNCT
bptjm-16	198	1	doi	doi	NOUN
bptjm-16	198	2	:	:	PUNCT
bptjm-16	198	3	10.1080/01926230701320337	10.1080/01926230701320337	NUM
bptjm-16	198	4	.	.	NOUN
bptjm-16	199	1	2	2	X
bptjm-16	199	2	.	.	X
bptjm-16	199	3	ling	ling	PROPN
bptjm-16	199	4	yh	yh	PROPN
bptjm-16	199	5	,	,	PUNCT
bptjm-16	199	6	waldemar	waldemar	PROPN
bptjm-16	199	7	p	p	PROPN
bptjm-16	199	8	,	,	PUNCT
bptjm-16	199	9	perez	perez	PROPN
bptjm-16	199	10	-	-	PUNCT
bptjm-16	199	11	soler	soler	PROPN
bptjm-16	199	12	r.	r.	PROPN
bptjm-16	199	13	apoptosis	apoptosis	PROPN
bptjm-16	199	14	induced	induce	VERB
bptjm-16	199	15	by	by	ADP
bptjm-16	199	16	anthracycline	anthracycline	PROPN
bptjm-16	199	17	in	in	ADP
bptjm-16	199	18	p388	p388	PROPN
bptjm-16	199	19	parent	parent	NOUN
bptjm-16	199	20	and	and	CCONJ
bptjm-16	199	21	multidrug	multidrug	NOUN
bptjm-16	199	22	-	-	PUNCT
bptjm-16	199	23	resistant	resistant	ADJ
bptjm-16	199	24	cells	cell	NOUN
bptjm-16	199	25	.	.	PUNCT
bptjm-16	200	1	cancer	cancer	NOUN
bptjm-16	200	2	res	re	NOUN
bptjm-16	200	3	.	.	PUNCT
bptjm-16	201	1	1993	1993	NUM
bptjm-16	201	2	apr	apr	NOUN
bptjm-16	201	3	15	15	NUM
bptjm-16	201	4	;	;	PUNCT
bptjm-16	201	5	53(8):1845	53(8):1845	NUM
bptjm-16	201	6	-	-	SYM
bptjm-16	201	7	52	52	NUM
bptjm-16	201	8	.	.	PUNCT
bptjm-16	202	1	3	3	X
bptjm-16	202	2	.	.	X
bptjm-16	202	3	ellis	ellis	PROPN
bptjm-16	202	4	,	,	PUNCT
bptjm-16	202	5	hm	hm	PROPN
bptjm-16	202	6	&	&	CCONJ
bptjm-16	202	7	horvitz	horvitz	PROPN
bptjm-16	202	8	,	,	PUNCT
bptjm-16	202	9	hr	hr	NOUN
bptjm-16	202	10	.	.	PUNCT
bptjm-16	203	1	genetic	genetic	ADJ
bptjm-16	203	2	control	control	NOUN
bptjm-16	203	3	of	of	ADP
bptjm-16	203	4	programmed	program	VERB
bptjm-16	203	5	cell	cell	NOUN
bptjm-16	203	6	death	death	NOUN
bptjm-16	203	7	in	in	ADP
bptjm-16	203	8	the	the	DET
bptjm-16	203	9	nematode	nematode	NOUN
bptjm-16	203	10	c.	c.	NOUN
bptjm-16	203	11	elegans	elegans	PROPN
bptjm-16	203	12	.	.	PUNCT
bptjm-16	204	1	cell	cell	NOUN
bptjm-16	204	2	.	.	PUNCT
bptjm-16	205	1	1986	1986	NUM
bptjm-16	205	2	mar	mar	PROPN
bptjm-16	205	3	28	28	NUM
bptjm-16	205	4	;	;	PUNCT
bptjm-16	205	5	44(6):817	44(6):817	PROPN
bptjm-16	205	6	-	-	PUNCT
bptjm-16	205	7	29	29	NUM
bptjm-16	205	8	.	.	PUNCT
bptjm-16	206	1	doi	doi	NOUN
bptjm-16	206	2	:	:	PUNCT
bptjm-16	206	3	10.1016/0092	10.1016/0092	NUM
bptjm-16	206	4	-	-	SYM
bptjm-16	206	5	8674(86)90004	8674(86)90004	NUM
bptjm-16	206	6	-	-	PUNCT
bptjm-16	206	7	8	8	NUM
bptjm-16	206	8	.	.	NOUN
bptjm-16	207	1	4	4	NUM
bptjm-16	207	2	.	.	X
bptjm-16	207	3	galluzzi	galluzzi	NOUN
bptjm-16	207	4	,	,	PUNCT
bptjm-16	207	5	l	l	PROPN
bptjm-16	207	6	et	et	PROPN
bptjm-16	207	7	al	al	PROPN
bptjm-16	207	8	.	.	PUNCT
bptjm-16	208	1	no	no	DET
bptjm-16	208	2	death	death	NOUN
bptjm-16	208	3	without	without	ADP
bptjm-16	208	4	life	life	NOUN
bptjm-16	208	5	:	:	PUNCT
bptjm-16	208	6	vital	vital	ADJ
bptjm-16	208	7	functions	function	NOUN
bptjm-16	208	8	of	of	ADP
bptjm-16	208	9	apoptotic	apoptotic	ADJ
bptjm-16	208	10	e	e	NOUN
bptjm-16	208	11	ectors	ector	NOUN
bptjm-16	208	12	.	.	PUNCT
bptjm-16	209	1	cell	cell	NOUN
bptjm-16	209	2	death	death	NOUN
bptjm-16	209	3	differ	differ	VERB
bptjm-16	209	4	.	.	PUNCT
bptjm-16	210	1	2008	2008	NUM
bptjm-16	210	2	jul	jul	NOUN
bptjm-16	210	3	;	;	PUNCT
bptjm-16	210	4	15(7):1113	15(7):1113	NUM
bptjm-16	210	5	-	-	SYM
bptjm-16	210	6	23	23	NUM
bptjm-16	210	7	.	.	PUNCT
bptjm-16	211	1	doi	doi	NOUN
bptjm-16	211	2	:	:	PUNCT
bptjm-16	211	3	10.1038	10.1038	NUM
bptjm-16	211	4	/	/	SYM
bptjm-16	211	5	cdd.2008.28	cdd.2008.28	PROPN
bptjm-16	211	6	.	.	PUNCT
bptjm-16	212	1	epub	epub	PROPN
bptjm-16	212	2	2008	2008	NUM
bptjm-16	212	3	feb	feb	NOUN
bptjm-16	212	4	29	29	NUM
bptjm-16	212	5	.	.	PUNCT
bptjm-16	213	1	5	5	NUM
bptjm-16	213	2	.	.	X
bptjm-16	213	3	garrido	garrido	PROPN
bptjm-16	213	4	,	,	PUNCT
bptjm-16	213	5	c	c	PROPN
bptjm-16	213	6	&	&	CCONJ
bptjm-16	213	7	kroemer	kroemer	PROPN
bptjm-16	213	8	,	,	PUNCT
bptjm-16	213	9	g.	g.	PROPN
bptjm-16	213	10	life	life	PROPN
bptjm-16	213	11	’s	’s	PART
bptjm-16	213	12	smile	smile	NOUN
bptjm-16	213	13	,	,	PUNCT
bptjm-16	213	14	death	death	NOUN
bptjm-16	213	15	’s	’s	PART
bptjm-16	213	16	grin	grin	NOUN
bptjm-16	213	17	:	:	PUNCT
bptjm-16	213	18	vital	vital	ADJ
bptjm-16	213	19	functions	function	NOUN
bptjm-16	213	20	of	of	ADP
bptjm-16	213	21	apoptosis	apoptosis	NOUN
bptjm-16	213	22	-	-	PUNCT
bptjm-16	213	23	executing	execute	VERB
bptjm-16	213	24	proteins	protein	NOUN
bptjm-16	213	25	.	.	PUNCT
bptjm-16	214	1	curr	curr	PROPN
bptjm-16	214	2	.	.	PUNCT
bptjm-16	215	1	opin	opin	NOUN
bptjm-16	215	2	.	.	PUNCT
bptjm-16	216	1	cell	cell	NOUN
bptjm-16	216	2	biol	biol	PROPN
bptjm-16	216	3	.	.	PUNCT
bptjm-16	217	1	2004	2004	NUM
bptjm-16	217	2	dec	dec	PROPN
bptjm-16	217	3	;	;	PUNCT
bptjm-16	217	4	16(6):639	16(6):639	PROPN
bptjm-16	217	5	-	-	SYM
bptjm-16	217	6	46	46	NUM
bptjm-16	217	7	.	.	PUNCT
bptjm-16	218	1	doi	doi	NOUN
bptjm-16	218	2	:	:	PUNCT
bptjm-16	218	3	10.1016	10.1016	NUM
bptjm-16	218	4	/	/	SYM
bptjm-16	218	5	j.ceb.2004.09.008	j.ceb.2004.09.008	NOUN
bptjm-16	218	6	.	.	PUNCT
bptjm-16	219	1	6	6	NUM
bptjm-16	219	2	.	.	X
bptjm-16	220	1	miura	miura	PROPN
bptjm-16	220	2	,	,	PUNCT
bptjm-16	220	3	m	m	PROPN
bptjm-16	220	4	,	,	PUNCT
bptjm-16	220	5	zhu	zhu	PROPN
bptjm-16	220	6	,	,	PUNCT
bptjm-16	220	7	h	h	NOUN
bptjm-16	220	8	,	,	PUNCT
bptjm-16	220	9	rotello	rotello	PROPN
bptjm-16	220	10	,	,	PUNCT
bptjm-16	220	11	r	r	NOUN
bptjm-16	220	12	,	,	PUNCT
bptjm-16	220	13	hartwieg	hartwieg	NOUN
bptjm-16	220	14	,	,	PUNCT
bptjm-16	220	15	ea	ea	PROPN
bptjm-16	220	16	&	&	CCONJ
bptjm-16	220	17	yuan	yuan	PROPN
bptjm-16	220	18	,	,	PUNCT
bptjm-16	220	19	j.	j.	PROPN
bptjm-16	220	20	induction	induction	NOUN
bptjm-16	220	21	of	of	ADP
bptjm-16	220	22	apoptosis	apoptosis	NOUN
bptjm-16	220	23	in	in	ADP
bptjm-16	220	24	broblasts	broblast	NOUN
bptjm-16	220	25	by	by	ADP
bptjm-16	220	26	il	il	PROPN
bptjm-16	220	27	1β	1β	ADJ
bptjm-16	220	28	-	-	PUNCT
bptjm-16	220	29	converting	convert	VERB
bptjm-16	220	30	enzyme	enzyme	NOUN
bptjm-16	220	31	,	,	PUNCT
bptjm-16	220	32	a	a	DET
bptjm-16	220	33	mammalian	mammalian	ADJ
bptjm-16	220	34	homolog	homolog	NOUN
bptjm-16	220	35	of	of	ADP
bptjm-16	220	36	the	the	DET
bptjm-16	220	37	c.	c.	PROPN
bptjm-16	220	38	elegans	elegans	PROPN
bptjm-16	220	39	cell	cell	NOUN
bptjm-16	220	40	death	death	NOUN
bptjm-16	220	41	gene	gene	NOUN
bptjm-16	220	42	ced-3	ced-3	NOUN
bptjm-16	220	43	.	.	PUNCT
bptjm-16	221	1	cell	cell	NOUN
bptjm-16	221	2	.	.	PUNCT
bptjm-16	222	1	1993	1993	NUM
bptjm-16	222	2	nov	nov	PROPN
bptjm-16	222	3	19	19	NUM
bptjm-16	222	4	;	;	PUNCT
bptjm-16	222	5	75(4):653	75(4):653	NUM
bptjm-16	222	6	-	-	SYM
bptjm-16	222	7	60	60	NUM
bptjm-16	222	8	.	.	PUNCT
bptjm-16	223	1	doi	doi	NOUN
bptjm-16	223	2	:	:	PUNCT
bptjm-16	223	3	10.1016/0092	10.1016/0092	NUM
bptjm-16	223	4	-	-	PUNCT
bptjm-16	223	5	8674(93)90486	8674(93)90486	NUM
bptjm-16	223	6	-	-	PUNCT
bptjm-16	223	7	a.	a.	NOUN
bptjm-16	223	8	6	6	NUM
bptjm-16	223	9	.	.	PUNCT
bptjm-16	224	1	li	li	PROPN
bptjm-16	224	2	n	n	PROPN
bptjm-16	224	3	jh	jh	PROPN
bptjm-16	224	4	,	,	PUNCT
bptjm-16	224	5	deng	deng	PROPN
bptjm-16	224	6	g	g	PROPN
bptjm-16	224	7	,	,	PUNCT
bptjm-16	224	8	huang	huang	PROPN
bptjm-16	224	9	qh	qh	PROPN
bptjm-16	224	10	,	,	PUNCT
bptjm-16	224	11	morser	morser	PROPN
bptjm-16	224	12	j	j	PROPN
bptjm-16	224	13	:	:	PUNCT
bptjm-16	224	14	kiap	kiap	PROPN
bptjm-16	224	15	,	,	PUNCT
bptjm-16	224	16	a	a	DET
bptjm-16	224	17	novel	novel	ADJ
bptjm-16	224	18	member	member	NOUN
bptjm-16	224	19	of	of	ADP
bptjm-16	224	20	the	the	DET
bptjm-16	224	21	inhibitor	inhibitor	NOUN
bptjm-16	224	22	of	of	ADP
bptjm-16	224	23	apoptosis	apoptosis	NOUN
bptjm-16	224	24	protein	protein	NOUN
bptjm-16	224	25	family	family	NOUN
bptjm-16	224	26	.	.	PUNCT
bptjm-16	225	1	biochem	biochem	PROPN
bptjm-16	225	2	biophys	biophy	VERB
bptjm-16	225	3	res	re	NOUN
bptjm-16	225	4	comm	comm	NOUN
bptjm-16	225	5	.	.	PUNCT
bptjm-16	226	1	2000	2000	NUM
bptjm-16	226	2	,	,	PUNCT
bptjm-16	226	3	279:820	279:820	NOUN
bptjm-16	226	4	-	-	PUNCT
bptjm-16	226	5	831	831	NUM
bptjm-16	226	6	.	.	PUNCT
bptjm-16	227	1	10.1006/	10.1006/	NUM
bptjm-16	227	2	bbrc.2000.4027	bbrc.2000.4027	ADJ
bptjm-16	227	3	.	.	PUNCT
bptjm-16	228	1	82	82	NUM
bptjm-16	228	2	.	.	PUNCT
bptjm-16	229	1	vucic	vucic	PROPN
bptjm-16	229	2	d	d	PROPN
bptjm-16	229	3	,	,	PUNCT
bptjm-16	229	4	stennicke	stennicke	PROPN
bptjm-16	229	5	hr	hr	PROPN
bptjm-16	229	6	,	,	PUNCT
bptjm-16	229	7	pisabarro	pisabarro	PROPN
bptjm-16	229	8	mt	mt	PROPN
bptjm-16	229	9	,	,	PUNCT
bptjm-16	229	10	salvesen	salvesen	PROPN
bptjm-16	229	11	gs	gs	PROPN
bptjm-16	229	12	,	,	PUNCT
bptjm-16	229	13	dixit	dixit	PROPN
bptjm-16	229	14	vm	vm	PROPN
bptjm-16	229	15	:	:	PUNCT
bptjm-16	229	16	ml	ml	PROPN
bptjm-16	229	17	-	-	PUNCT
bptjm-16	229	18	iap	iap	PROPN
bptjm-16	229	19	,	,	PUNCT
bptjm-16	229	20	a	a	DET
bptjm-16	229	21	novel	novel	ADJ
bptjm-16	229	22	inhibitor	inhibitor	NOUN
bptjm-16	229	23	of	of	ADP
bptjm-16	229	24	apoptosis	apoptosis	NOUN
bptjm-16	229	25	that	that	PRON
bptjm-16	229	26	is	be	AUX
bptjm-16	229	27	preferentially	preferentially	ADV
bptjm-16	229	28	expressed	express	VERB
bptjm-16	229	29	in	in	ADP
bptjm-16	229	30	human	human	ADJ
bptjm-16	229	31	melanomas	melanomas	NOUN
bptjm-16	229	32	.	.	PUNCT
bptjm-16	230	1	curr	curr	PROPN
bptjm-16	230	2	biol	biol	PROPN
bptjm-16	230	3	.	.	PUNCT
bptjm-16	231	1	2000	2000	NUM
bptjm-16	231	2	,	,	PUNCT
bptjm-16	231	3	10:1359	10:1359	NUM
bptjm-16	231	4	-	-	SYM
bptjm-16	231	5	1366	1366	NUM
bptjm-16	231	6	.	.	PUNCT
bptjm-16	232	1	10.1016	10.1016	NUM
bptjm-16	232	2	/	/	SYM
bptjm-16	232	3	s0960	s0960	PROPN
bptjm-16	232	4	-	-	PUNCT
bptjm-16	232	5	9822(00)00781	9822(00)00781	NUM
bptjm-16	232	6	-	-	SYM
bptjm-16	232	7	8	8	NUM
bptjm-16	232	8	.	.	X
bptjm-16	232	9	7	7	NUM
bptjm-16	232	10	.	.	NUM
bptjm-16	232	11	yoneda	yoneda	PROPN
bptjm-16	232	12	,	,	PUNCT
bptjm-16	232	13	t	t	PROPN
bptjm-16	232	14	et	et	PROPN
bptjm-16	232	15	al	al	PROPN
bptjm-16	232	16	.	.	PROPN
bptjm-16	232	17	activation	activation	NOUN
bptjm-16	232	18	of	of	ADP
bptjm-16	232	19	caspase-12	caspase-12	PROPN
bptjm-16	232	20	,	,	PUNCT
bptjm-16	232	21	an	an	DET
bptjm-16	232	22	endoplastic	endoplastic	ADJ
bptjm-16	232	23	reticulum	reticulum	NOUN
bptjm-16	232	24	(	(	PUNCT
bptjm-16	232	25	er	er	INTJ
bptjm-16	232	26	)	)	PUNCT
bptjm-16	232	27	resident	resident	NOUN
bptjm-16	232	28	caspase	caspase	NOUN
bptjm-16	232	29	,	,	PUNCT
bptjm-16	232	30	through	through	ADP
bptjm-16	232	31	tumor	tumor	NOUN
bptjm-16	232	32	necrosis	necrosis	NOUN
bptjm-16	232	33	factor	factor	NOUN
bptjm-16	232	34	receptor	receptor	NOUN
bptjm-16	232	35	-	-	PUNCT
bptjm-16	232	36	associated	associate	VERB
bptjm-16	232	37	factor	factor	NOUN
bptjm-16	232	38	2	2	NUM
bptjm-16	232	39	-	-	PUNCT
bptjm-16	232	40	dependent	dependent	ADJ
bptjm-16	232	41	mechanism	mechanism	NOUN
bptjm-16	232	42	in	in	ADP
bptjm-16	232	43	response	response	NOUN
bptjm-16	232	44	to	to	ADP
bptjm-16	232	45	the	the	DET
bptjm-16	232	46	er	er	INTJ
bptjm-16	232	47	stress	stress	NOUN
bptjm-16	232	48	.	.	PUNCT
bptjm-16	233	1	j.	j.	PROPN
bptjm-16	233	2	biol	biol	PROPN
bptjm-16	233	3	.	.	PUNCT
bptjm-16	234	1	chem	chem	PROPN
bptjm-16	234	2	.	.	PUNCT
bptjm-16	235	1	2001	2001	NUM
bptjm-16	235	2	apr	apr	NOUN
bptjm-16	235	3	27	27	NUM
bptjm-16	235	4	;	;	PUNCT
bptjm-16	235	5	276(17):13935	276(17):13935	NUM
bptjm-16	235	6	-	-	SYM
bptjm-16	235	7	40	40	NUM
bptjm-16	235	8	.	.	PUNCT
bptjm-16	236	1	doi	doi	NOUN
bptjm-16	236	2	:	:	PUNCT
bptjm-16	236	3	10.1074	10.1074	NUM
bptjm-16	236	4	/	/	SYM
bptjm-16	236	5	jbc.m010677200	jbc.m010677200	NOUN
bptjm-16	236	6	.	.	PUNCT
bptjm-16	237	1	epub	epub	PROPN
bptjm-16	237	2	2001	2001	NUM
bptjm-16	237	3	jan	jan	PROPN
bptjm-16	237	4	29	29	NUM
bptjm-16	237	5	.	.	PUNCT
bptjm-16	237	6	8	8	NUM
bptjm-16	237	7	.	.	X
bptjm-16	238	1	chen	chen	PROPN
bptjm-16	239	1	q	q	PROPN
bptjm-16	239	2	,	,	PUNCT
bptjm-16	239	3	kang	kang	PROPN
bptjm-16	239	4	j	j	PROPN
bptjm-16	239	5	,	,	PUNCT
bptjm-16	239	6	fu	fu	PROPN
bptjm-16	239	7	c.	c.	PROPN
bptjm-16	239	8	the	the	DET
bptjm-16	239	9	independence	independence	NOUN
bptjm-16	239	10	of	of	ADP
bptjm-16	239	11	and	and	CCONJ
bptjm-16	239	12	associations	association	NOUN
bptjm-16	239	13	among	among	ADP
bptjm-16	239	14	apoptosis	apoptosis	NOUN
bptjm-16	239	15	,	,	PUNCT
bptjm-16	239	16	autophagy	autophagy	NOUN
bptjm-16	239	17	,	,	PUNCT
bptjm-16	239	18	and	and	CCONJ
bptjm-16	239	19	necrosis	necrosis	NOUN
bptjm-16	239	20	.	.	PUNCT
bptjm-16	240	1	signal	signal	ADJ
bptjm-16	240	2	transduction	transduction	NOUN
bptjm-16	240	3	and	and	CCONJ
bptjm-16	240	4	targeted	target	VERB
bptjm-16	240	5	therapy	therapy	NOUN
bptjm-16	240	6	.	.	PUNCT
bptjm-16	241	1	2018	2018	NUM
bptjm-16	241	2	jul	jul	PROPN
bptjm-16	241	3	1	1	NUM
bptjm-16	241	4	;	;	PUNCT
bptjm-16	241	5	3:18	3:18	NUM
bptjm-16	241	6	.	.	PUNCT
bptjm-16	242	1	doi	doi	PROPN
bptjm-16	242	2	:	:	PUNCT
bptjm-16	242	3	10.1038/	10.1038/	NUM
bptjm-16	242	4	s41392	s41392	PROPN
bptjm-16	242	5	-	-	PUNCT
bptjm-16	242	6	018	018	NUM
bptjm-16	242	7	-	-	PUNCT
bptjm-16	242	8	0018	0018	NUM
bptjm-16	242	9	-	-	SYM
bptjm-16	242	10	5	5	NUM
bptjm-16	242	11	.	.	NOUN
bptjm-16	242	12	9	9	NUM
bptjm-16	242	13	.	.	X
bptjm-16	242	14	xu	xu	PROPN
bptjm-16	242	15	t	t	PROPN
bptjm-16	242	16	,	,	PUNCT
bptjm-16	242	17	ding	de	VERB
bptjm-16	242	18	w	w	PROPN
bptjm-16	242	19	,	,	PUNCT
bptjm-16	242	20	tariq	tariq	PROPN
bptjm-16	242	21	ma	ma	PROPN
bptjm-16	242	22	,	,	PUNCT
bptjm-16	242	23	et	et	PROPN
bptjm-16	242	24	al	al	PROPN
bptjm-16	242	25	.	.	PUNCT
bptjm-16	243	1	molecular	molecular	ADJ
bptjm-16	243	2	mechanism	mechanism	NOUN
bptjm-16	243	3	and	and	CCONJ
bptjm-16	243	4	therapy	therapy	NOUN
bptjm-16	243	5	application	application	NOUN
bptjm-16	243	6	of	of	ADP
bptjm-16	243	7	necrosis	necrosis	NOUN
bptjm-16	243	8	during	during	ADP
bptjm-16	243	9	myocardial	myocardial	ADJ
bptjm-16	243	10	injury	injury	NOUN
bptjm-16	243	11	.	.	PUNCT
bptjm-16	244	1	journal	journal	NOUN
bptjm-16	244	2	of	of	ADP
bptjm-16	244	3	cellular	cellular	ADJ
bptjm-16	244	4	and	and	CCONJ
bptjm-16	244	5	molecular	molecular	ADJ
bptjm-16	244	6	medicine	medicine	NOUN
bptjm-16	244	7	.	.	PUNCT
bptjm-16	245	1	2018	2018	NUM
bptjm-16	245	2	;	;	PUNCT
bptjm-16	245	3	22(5):2547	22(5):2547	NUM
bptjm-16	245	4	-	-	SYM
bptjm-16	245	5	2557	2557	NUM
bptjm-16	245	6	.	.	PUNCT
bptjm-16	246	1	doi:10.1111	doi:10.1111	NOUN
bptjm-16	246	2	/	/	SYM
bptjm-16	246	3	jcmm.13575	jcmm.13575	PROPN
bptjm-16	246	4	10	10	NUM
bptjm-16	246	5	.	.	PUNCT
bptjm-16	247	1	chen	chen	PROPN
bptjm-16	247	2	j	j	PROPN
bptjm-16	247	3	,	,	PUNCT
bptjm-16	247	4	kos	kos	PROPN
bptjm-16	247	5	r	r	PROPN
bptjm-16	247	6	,	,	PUNCT
bptjm-16	247	7	garssen	garssen	ADJ
bptjm-16	247	8	j	j	PROPN
bptjm-16	247	9	,	,	PUNCT
bptjm-16	247	10	redegeld	redegeld	VERB
bptjm-16	247	11	f.	f.	PROPN
bptjm-16	247	12	molecular	molecular	ADJ
bptjm-16	247	13	insights	insight	NOUN
bptjm-16	247	14	into	into	ADP
bptjm-16	247	15	the	the	DET
bptjm-16	247	16	mechanism	mechanism	NOUN
bptjm-16	247	17	of	of	ADP
bptjm-16	247	18	necroptosis	necroptosis	NOUN
bptjm-16	247	19	:	:	PUNCT
bptjm-16	247	20	the	the	DET
bptjm-16	247	21	necrosome	necrosome	NOUN
bptjm-16	247	22	as	as	ADP
bptjm-16	247	23	a	a	DET
bptjm-16	247	24	potential	potential	ADJ
bptjm-16	247	25	therapeutic	therapeutic	ADJ
bptjm-16	247	26	target	target	NOUN
bptjm-16	247	27	.	.	PUNCT
bptjm-16	248	1	cell	cell	NOUN
bptjm-16	248	2	.	.	PUNCT
bptjm-16	249	1	2019	2019	NUM
bptjm-16	249	2	nov	nov	PROPN
bptjm-16	249	3	21	21	NUM
bptjm-16	249	4	;	;	PUNCT
bptjm-16	249	5	8(12	8(12	NUM
bptjm-16	249	6	):	):	PUNCT
bptjm-16	249	7	1486	1486	NUM
bptjm-16	249	8	.	.	PUNCT
bptjm-16	250	1	https://doi.org/10.3390/cells8121486	https://doi.org/10.3390/cells8121486	NOUN
bptjm-16	250	2	11	11	NUM
bptjm-16	250	3	.	.	PUNCT
bptjm-16	251	1	lavrik	lavrik	NOUN
bptjm-16	251	2	,	,	PUNCT
bptjm-16	251	3	i	i	PRON
bptjm-16	251	4	,	,	PUNCT
bptjm-16	251	5	golks	golks	PROPN
bptjm-16	251	6	,	,	PUNCT
bptjm-16	251	7	a	a	PRON
bptjm-16	251	8	&	&	CCONJ
bptjm-16	251	9	krammer	krammer	NOUN
bptjm-16	251	10	,	,	PUNCT
bptjm-16	251	11	ph	ph	PROPN
bptjm-16	251	12	.	.	PROPN
bptjm-16	251	13	death	death	NOUN
bptjm-16	251	14	receptor	receptor	NOUN
bptjm-16	251	15	signaling	signal	VERB
bptjm-16	251	16	.	.	PUNCT
bptjm-16	252	1	j.	j.	PROPN
bptjm-16	252	2	cell	cell	PROPN
bptjm-16	252	3	sci	sci	PROPN
bptjm-16	252	4	.	.	PROPN
bptjm-16	252	5	2005	2005	NUM
bptjm-16	252	6	jan	jan	PROPN
bptjm-16	252	7	15	15	NUM
bptjm-16	252	8	;	;	PUNCT
bptjm-16	252	9	118(pt	118(pt	NUM
bptjm-16	252	10	2):265	2):265	NUM
bptjm-16	252	11	-	-	SYM
bptjm-16	252	12	7	7	NUM
bptjm-16	252	13	.	.	PUNCT
bptjm-16	252	14	doi	doi	NOUN
bptjm-16	252	15	:	:	PUNCT
bptjm-16	252	16	10.1242	10.1242	NUM
bptjm-16	252	17	/	/	SYM
bptjm-16	252	18	jcs.01610	jcs.01610	NUM
bptjm-16	252	19	.	.	PUNCT
bptjm-16	253	1	12	12	NUM
bptjm-16	253	2	.	.	PUNCT
bptjm-16	254	1	wang	wang	PROPN
bptjm-16	254	2	,	,	PUNCT
bptjm-16	254	3	s	s	PROPN
bptjm-16	254	4	&	&	CCONJ
bptjm-16	254	5	el	el	PROPN
bptjm-16	254	6	-	-	PUNCT
bptjm-16	254	7	deiry	deiry	PROPN
bptjm-16	254	8	,	,	PUNCT
bptjm-16	254	9	ws	ws	NOUN
bptjm-16	254	10	.	.	PUNCT
bptjm-16	255	1	trail	trail	NOUN
bptjm-16	255	2	and	and	CCONJ
bptjm-16	255	3	apoptosis	apoptosis	NOUN
bptjm-16	255	4	induction	induction	NOUN
bptjm-16	255	5	by	by	ADP
bptjm-16	255	6	tnf	tnf	PROPN
bptjm-16	255	7	-	-	PUNCT
bptjm-16	255	8	family	family	NOUN
bptjm-16	255	9	death	death	NOUN
bptjm-16	255	10	receptors	receptor	NOUN
bptjm-16	255	11	.	.	PUNCT
bptjm-16	256	1	oncogene	oncogene	NOUN
bptjm-16	256	2	.	.	PUNCT
bptjm-16	257	1	2003	2003	NUM
bptjm-16	257	2	nov	nov	NOUN
bptjm-16	257	3	24	24	NUM
bptjm-16	257	4	;	;	PUNCT
bptjm-16	257	5	22(53):8628	22(53):8628	NUM
bptjm-16	257	6	-	-	SYM
bptjm-16	257	7	33	33	NUM
bptjm-16	257	8	.	.	PUNCT
bptjm-16	258	1	doi	doi	NOUN
bptjm-16	258	2	:	:	PUNCT
bptjm-16	258	3	10.1038	10.1038	NUM
bptjm-16	258	4	/	/	SYM
bptjm-16	258	5	sj.onc.1207232	sj.onc.1207232	NOUN
bptjm-16	258	6	.	.	PROPN
bptjm-16	259	1	13	13	NUM
bptjm-16	259	2	.	.	PUNCT
bptjm-16	259	3	iannielli	iannielli	PROPN
bptjm-16	259	4	a.	a.	PROPN
bptjm-16	259	5	,	,	PUNCT
bptjm-16	259	6	bido	bido	PROPN
bptjm-16	259	7	s.	s.	PROPN
bptjm-16	259	8	,	,	PUNCT
bptjm-16	259	9	folladori	folladori	PROPN
bptjm-16	259	10	l.	l.	PROPN
bptjm-16	259	11	,	,	PUNCT
bptjm-16	259	12	segnali	segnali	PROPN
bptjm-16	259	13	a.	a.	PROPN
bptjm-16	259	14	,	,	PUNCT
bptjm-16	259	15	cancellieri	cancellieri	PROPN
bptjm-16	259	16	c.	c.	PROPN
bptjm-16	259	17	,	,	PUNCT
bptjm-16	259	18	maresca	maresca	ADJ
bptjm-16	259	19	a.	a.	NOUN
bptjm-16	259	20	,	,	PUNCT
bptjm-16	259	21	massimino	massimino	PROPN
bptjm-16	259	22	l.	l.	PROPN
bptjm-16	259	23	,	,	PUNCT
bptjm-16	259	24	rubio	rubio	PROPN
bptjm-16	259	25	a.	a.	PROPN
bptjm-16	259	26	,	,	PUNCT
bptjm-16	259	27	morabito	morabito	PROPN
bptjm-16	259	28	g.	g.	PROPN
bptjm-16	259	29	,	,	PUNCT
bptjm-16	259	30	caporali	caporali	PROPN
bptjm-16	259	31	l.	l.	PROPN
bptjm-16	259	32	,	,	PUNCT
bptjm-16	259	33	et	et	PROPN
bptjm-16	259	34	al	al	PROPN
bptjm-16	259	35	.	.	PUNCT
bptjm-16	259	36	pharmacological	pharmacological	ADJ
bptjm-16	259	37	inhibition	inhibition	NOUN
bptjm-16	259	38	of	of	ADP
bptjm-16	259	39	necroptosis	necroptosis	NOUN
bptjm-16	259	40	protects	protect	NOUN
bptjm-16	259	41	from	from	ADP
bptjm-16	259	42	dopaminergic	dopaminergic	ADJ
bptjm-16	259	43	neuronal	neuronal	ADJ
bptjm-16	259	44	cell	cell	NOUN
bptjm-16	259	45	death	death	NOUN
bptjm-16	259	46	in	in	ADP
bptjm-16	259	47	parkinson	parkinson	NOUN
bptjm-16	259	48	’s	’s	PART
bptjm-16	259	49	disease	disease	NOUN
bptjm-16	259	50	models	model	NOUN
bptjm-16	259	51	.	.	PUNCT
bptjm-16	260	1	cell	cell	NOUN
bptjm-16	260	2	rep	rep	PROPN
bptjm-16	260	3	.	.	PROPN
bptjm-16	260	4	2018	2018	NUM
bptjm-16	260	5	;	;	PUNCT
bptjm-16	260	6	22:2066	22:2066	NUM
bptjm-16	260	7	–	–	PUNCT
bptjm-16	260	8	2079	2079	NUM
bptjm-16	260	9	.	.	PUNCT
bptjm-16	261	1	doi	doi	NOUN
bptjm-16	261	2	:	:	PUNCT
bptjm-16	261	3	10.1016	10.1016	NUM
bptjm-16	261	4	/	/	SYM
bptjm-16	261	5	j.celrep.2018.01.089	j.celrep.2018.01.089	PROPN
bptjm-16	261	6	berkeley	berkeley	PROPN
bptjm-16	261	7	pharma	pharma	PROPN
bptjm-16	261	8	tech	tech	NOUN
bptjm-16	261	9	journal	journal	NOUN
bptjm-16	261	10	of	of	ADP
bptjm-16	261	11	medicine	medicine	NOUN
bptjm-16	261	12	|	|	ADV
bptjm-16	261	13	110	110	NUM
bptjm-16	261	14	14	14	NUM
bptjm-16	261	15	.	.	PUNCT
bptjm-16	262	1	jhun	jhun	PROPN
bptjm-16	262	2	j.	j.	PROPN
bptjm-16	262	3	,	,	PUNCT
bptjm-16	262	4	lee	lee	PROPN
bptjm-16	262	5	s.h	s.h	PROPN
bptjm-16	262	6	.	.	PROPN
bptjm-16	262	7	,	,	PUNCT
bptjm-16	262	8	kim	kim	PROPN
bptjm-16	262	9	s.y	s.y	PROPN
bptjm-16	262	10	.	.	PROPN
bptjm-16	262	11	,	,	PUNCT
bptjm-16	262	12	ryu	ryu	PROPN
bptjm-16	262	13	j.	j.	PROPN
bptjm-16	262	14	,	,	PUNCT
bptjm-16	262	15	kwon	kwon	VERB
bptjm-16	262	16	j.y	j.y	PROPN
bptjm-16	262	17	.	.	PROPN
bptjm-16	262	18	,	,	PUNCT
bptjm-16	262	19	na	na	PROPN
bptjm-16	262	20	h.s	h.s	PROPN
bptjm-16	262	21	.	.	PROPN
bptjm-16	262	22	,	,	PUNCT
bptjm-16	262	23	jung	jung	PROPN
bptjm-16	262	24	k.	k.	PROPN
bptjm-16	262	25	,	,	PUNCT
bptjm-16	262	26	moon	moon	PROPN
bptjm-16	262	27	s.j	s.j	PROPN
bptjm-16	262	28	.	.	PROPN
bptjm-16	262	29	,	,	PUNCT
bptjm-16	262	30	cho	cho	PROPN
bptjm-16	263	1	m.l	m.l	PROPN
bptjm-16	263	2	.	.	PROPN
bptjm-16	263	3	,	,	PUNCT
bptjm-16	263	4	min	min	PROPN
bptjm-16	263	5	j.k	j.k	PROPN
bptjm-16	263	6	.	.	PUNCT
bptjm-16	263	7	ripk1	ripk1	NOUN
bptjm-16	263	8	inhibition	inhibition	NOUN
bptjm-16	263	9	attenuates	attenuate	VERB
bptjm-16	263	10	experimental	experimental	ADJ
bptjm-16	263	11	autoimmune	autoimmune	ADJ
bptjm-16	263	12	arthritis	arthritis	NOUN
bptjm-16	263	13	via	via	ADP
bptjm-16	263	14	suppression	suppression	NOUN
bptjm-16	263	15	of	of	ADP
bptjm-16	263	16	osteoclastogenesis	osteoclastogenesis	NOUN
bptjm-16	263	17	.	.	PUNCT
bptjm-16	264	1	j.	j.	PROPN
bptjm-16	264	2	transl	transl	PROPN
bptjm-16	264	3	.	.	PUNCT
bptjm-16	265	1	med	med	PROPN
bptjm-16	265	2	.	.	PROPN
bptjm-16	266	1	2019	2019	NUM
bptjm-16	266	2	;	;	PUNCT
bptjm-16	266	3	17:84	17:84	NUM
bptjm-16	266	4	.	.	PUNCT
bptjm-16	267	1	doi	doi	NOUN
bptjm-16	267	2	:	:	PUNCT
bptjm-16	267	3	10.1186	10.1186	NUM
bptjm-16	267	4	/	/	SYM
bptjm-16	267	5	s12967	s12967	NOUN
bptjm-16	267	6	-	-	PUNCT
bptjm-16	267	7	019	019	NUM
bptjm-16	267	8	-	-	PUNCT
bptjm-16	267	9	1809	1809	NUM
bptjm-16	267	10	-	-	SYM
bptjm-16	267	11	3	3	NUM
bptjm-16	267	12	15	15	NUM
bptjm-16	267	13	.	.	PUNCT
bptjm-16	268	1	ito	ito	PROPN
bptjm-16	268	2	y.	y.	PROPN
bptjm-16	268	3	,	,	PUNCT
bptjm-16	268	4	ofengeim	ofengeim	PROPN
bptjm-16	268	5	d.	d.	PROPN
bptjm-16	268	6	,	,	PUNCT
bptjm-16	268	7	najafov	najafov	PROPN
bptjm-16	268	8	a.	a.	PROPN
bptjm-16	268	9	,	,	PUNCT
bptjm-16	268	10	das	das	PROPN
bptjm-16	268	11	s.	s.	PROPN
bptjm-16	268	12	,	,	PUNCT
bptjm-16	268	13	saberi	saberi	PROPN
bptjm-16	268	14	s.	s.	PROPN
bptjm-16	268	15	,	,	PUNCT
bptjm-16	268	16	li	li	PROPN
bptjm-16	268	17	y.	y.	PROPN
bptjm-16	268	18	,	,	PUNCT
bptjm-16	268	19	hitomi	hitomi	PROPN
bptjm-16	268	20	j.	j.	PROPN
bptjm-16	268	21	,	,	PUNCT
bptjm-16	268	22	zhu	zhu	PROPN
bptjm-16	268	23	h.	h.	PROPN
bptjm-16	268	24	,	,	PUNCT
bptjm-16	268	25	chen	chen	PROPN
bptjm-16	268	26	h.	h.	PROPN
bptjm-16	268	27	,	,	PUNCT
bptjm-16	268	28	mayo	mayo	PROPN
bptjm-16	268	29	l.	l.	PROPN
bptjm-16	268	30	,	,	PUNCT
bptjm-16	268	31	et	et	PROPN
bptjm-16	268	32	al	al	PROPN
bptjm-16	268	33	.	.	PUNCT
bptjm-16	269	1	ripk1	ripk1	PROPN
bptjm-16	269	2	mediates	mediate	VERB
bptjm-16	269	3	axonal	axonal	ADJ
bptjm-16	269	4	degeneration	degeneration	NOUN
bptjm-16	269	5	by	by	ADP
bptjm-16	269	6	promoting	promote	VERB
bptjm-16	269	7	in	in	ADP
bptjm-16	269	8	ammation	ammation	NOUN
bptjm-16	269	9	and	and	CCONJ
bptjm-16	269	10	necroptosis	necroptosis	NOUN
bptjm-16	269	11	in	in	ADP
bptjm-16	269	12	als	al	NOUN
bptjm-16	269	13	.	.	PUNCT
bptjm-16	270	1	science	science	NOUN
bptjm-16	270	2	.	.	PUNCT
bptjm-16	271	1	2016	2016	NUM
bptjm-16	271	2	;	;	PUNCT
bptjm-16	271	3	353:603–608	353:603–608	NUM
bptjm-16	271	4	.	.	PUNCT
bptjm-16	272	1	doi	doi	NOUN
bptjm-16	272	2	:	:	PUNCT
bptjm-16	272	3	10.1126	10.1126	NUM
bptjm-16	272	4	/	/	SYM
bptjm-16	272	5	science.aaf6803	science.aaf6803	PROPN
bptjm-16	272	6	16	16	NUM
bptjm-16	272	7	.	.	PUNCT
bptjm-16	273	1	gupta	gupta	PROPN
bptjm-16	273	2	k	k	PROPN
bptjm-16	273	3	,	,	PUNCT
bptjm-16	273	4	phan	phan	PROPN
bptjm-16	273	5	n	n	CCONJ
bptjm-16	273	6	,	,	PUNCT
bptjm-16	273	7	wang	wang	PROPN
bptjm-16	273	8	q	q	PROPN
bptjm-16	273	9	,	,	PUNCT
bptjm-16	273	10	liu	liu	PROPN
bptjm-16	273	11	b.	b.	PROPN
bptjm-16	273	12	necroptosis	necroptosis	PROPN
bptjm-16	273	13	in	in	ADP
bptjm-16	273	14	cardiovascular	cardiovascular	ADJ
bptjm-16	273	15	disease	disease	NOUN
bptjm-16	273	16	a	a	DET
bptjm-16	273	17	new	new	ADJ
bptjm-16	273	18	therapeutic	therapeutic	ADJ
bptjm-16	273	19	target	target	NOUN
bptjm-16	273	20	.	.	PUNCT
bptjm-16	274	1	j	j	PROPN
bptjm-16	274	2	mol	mol	PROPN
bptjm-16	274	3	cell	cell	NOUN
bptjm-16	274	4	cardiol	cardiol	NOUN
bptjm-16	274	5	.	.	PUNCT
bptjm-16	275	1	2018	2018	NUM
bptjm-16	275	2	may	may	AUX
bptjm-16	275	3	;	;	PUNCT
bptjm-16	275	4	118:26	118:26	NUM
bptjm-16	275	5	-	-	SYM
bptjm-16	275	6	35	35	NUM
bptjm-16	275	7	.	.	PUNCT
bptjm-16	276	1	doi	doi	NOUN
bptjm-16	276	2	:	:	PUNCT
bptjm-16	276	3	10.1016	10.1016	NUM
bptjm-16	276	4	/	/	SYM
bptjm-16	276	5	j.yjmcc.2018.03.003	j.yjmcc.2018.03.003	NOUN
bptjm-16	276	6	.	.	PROPN
bptjm-16	276	7	17	17	NUM
bptjm-16	276	8	.	.	PUNCT
bptjm-16	277	1	bretz	bretz	PROPN
bptjm-16	277	2	jd	jd	PROPN
bptjm-16	277	3	,	,	PUNCT
bptjm-16	277	4	rymaszewski	rymaszewski	PROPN
bptjm-16	277	5	m	m	PROPN
bptjm-16	277	6	,	,	PUNCT
bptjm-16	277	7	arscott	arscott	PROPN
bptjm-16	277	8	pl	pl	PROPN
bptjm-16	277	9	,	,	PUNCT
bptjm-16	277	10	myc	myc	PROPN
bptjm-16	277	11	a	a	NOUN
bptjm-16	277	12	,	,	PUNCT
bptjm-16	277	13	ain	ain	PROPN
bptjm-16	277	14	kb	kb	PROPN
bptjm-16	277	15	,	,	PUNCT
bptjm-16	277	16	thompson	thompson	PROPN
bptjm-16	277	17	nw	nw	PROPN
bptjm-16	277	18	,	,	PUNCT
bptjm-16	277	19	baker	baker	PROPN
bptjm-16	277	20	jr	jr	PROPN
bptjm-16	277	21	jr	jr	PROPN
bptjm-16	277	22	.	.	PROPN
bptjm-16	277	23	trail	trail	PROPN
bptjm-16	277	24	death	death	NOUN
bptjm-16	277	25	pathway	pathway	NOUN
bptjm-16	277	26	expression	expression	NOUN
bptjm-16	277	27	and	and	CCONJ
bptjm-16	277	28	induction	induction	NOUN
bptjm-16	277	29	in	in	ADP
bptjm-16	277	30	thyroid	thyroid	NOUN
bptjm-16	277	31	follicular	follicular	ADJ
bptjm-16	277	32	cells	cell	NOUN
bptjm-16	277	33	.	.	PUNCT
bptjm-16	278	1	j	j	PROPN
bptjm-16	278	2	biol	biol	PROPN
bptjm-16	278	3	chem	chem	PROPN
bptjm-16	278	4	.	.	PUNCT
bptjm-16	279	1	1999	1999	NUM
bptjm-16	279	2	aug	aug	PROPN
bptjm-16	279	3	13	13	NUM
bptjm-16	279	4	;	;	PUNCT
bptjm-16	279	5	274(33):23627	274(33):23627	PROPN
bptjm-16	279	6	-	-	SYM
bptjm-16	279	7	32	32	NUM
bptjm-16	279	8	.	.	PUNCT
bptjm-16	280	1	doi	doi	NOUN
bptjm-16	280	2	:	:	PUNCT
bptjm-16	280	3	10.1074	10.1074	NUM
bptjm-16	280	4	/	/	SYM
bptjm-16	280	5	jbc.274.33.23627	jbc.274.33.23627	PROPN
bptjm-16	280	6	.	.	PROPN
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bptjm-16	280	8	.	.	PUNCT
bptjm-16	281	1	kawakami	kawakami	PROPN
bptjm-16	281	2	a	a	PROPN
bptjm-16	281	3	,	,	PUNCT
bptjm-16	281	4	matsuoka	matsuoka	NOUN
bptjm-16	281	5	n	n	CCONJ
bptjm-16	281	6	,	,	PUNCT
bptjm-16	281	7	tsuboi	tsuboi	PROPN
bptjm-16	281	8	m	m	PROPN
bptjm-16	281	9	,	,	PUNCT
bptjm-16	281	10	koji	koji	PROPN
bptjm-16	281	11	t	t	PROPN
bptjm-16	281	12	,	,	PUNCT
bptjm-16	281	13	urayama	urayama	NOUN
bptjm-16	281	14	s	s	PROPN
bptjm-16	281	15	,	,	PUNCT
bptjm-16	281	16	sera	sera	NOUN
bptjm-16	281	17	n	n	PROPN
bptjm-16	281	18	,	,	PUNCT
bptjm-16	281	19	hida	hida	PROPN
bptjm-16	281	20	a	a	PROPN
bptjm-16	281	21	,	,	PUNCT
bptjm-16	281	22	usa	usa	PROPN
bptjm-16	281	23	t	t	PROPN
bptjm-16	281	24	,	,	PUNCT
bptjm-16	281	25	kimura	kimura	NOUN
bptjm-16	281	26	h	h	NOUN
bptjm-16	281	27	,	,	PUNCT
bptjm-16	281	28	yokoyama	yokoyama	PROPN
bptjm-16	281	29	n	n	CCONJ
bptjm-16	281	30	,	,	PUNCT
bptjm-16	281	31	nakashima	nakashima	PROPN
bptjm-16	281	32	t	t	PROPN
bptjm-16	281	33	,	,	PUNCT
bptjm-16	281	34	ishikawa	ishikawa	PROPN
bptjm-16	281	35	n	n	CCONJ
bptjm-16	281	36	,	,	PUNCT
bptjm-16	281	37	ito	ito	PROPN
bptjm-16	281	38	k	k	PROPN
bptjm-16	281	39	,	,	PUNCT
bptjm-16	281	40	kawabe	kawabe	PROPN
bptjm-16	281	41	y	y	PROPN
bptjm-16	281	42	,	,	PUNCT
bptjm-16	281	43	eguchi	eguchi	X
bptjm-16	281	44	k.	k.	PROPN
bptjm-16	282	1	cd4	cd4	PROPN
bptjm-16	282	2	+	+	PROPN
bptjm-16	282	3	t	t	PROPN
bptjm-16	282	4	cell	cell	NOUN
bptjm-16	282	5	mediated	mediate	VERB
bptjm-16	282	6	cytotoxicity	cytotoxicity	NOUN
bptjm-16	282	7	toward	toward	ADP
bptjm-16	282	8	thyrocytes	thyrocyte	NOUN
bptjm-16	282	9	:	:	PUNCT
bptjm-16	282	10	the	the	DET
bptjm-16	282	11	importance	importance	NOUN
bptjm-16	282	12	of	of	ADP
bptjm-16	282	13	fas	fas	ADJ
bptjm-16	282	14	/	/	SYM
bptjm-16	282	15	fas	fas	PROPN
bptjm-16	282	16	ligand	ligand	NOUN
bptjm-16	282	17	interaction	interaction	NOUN
bptjm-16	282	18	inducing	induce	VERB
bptjm-16	282	19	apoptosis	apoptosis	NOUN
bptjm-16	282	20	of	of	ADP
bptjm-16	282	21	thyrocytes	thyrocyte	NOUN
bptjm-16	282	22	and	and	CCONJ
bptjm-16	282	23	the	the	DET
bptjm-16	282	24	inhibitory	inhibitory	ADJ
bptjm-16	282	25	e	e	X
bptjm-16	282	26	ect	ect	X
bptjm-16	282	27	of	of	ADP
bptjm-16	282	28	thyroid	thyroid	NOUN
bptjm-16	282	29	-	-	PUNCT
bptjm-16	282	30	stimulating	stimulate	VERB
bptjm-16	282	31	hormone	hormone	NOUN
bptjm-16	282	32	.	.	PUNCT
bptjm-16	283	1	lab	lab	NOUN
bptjm-16	283	2	invest	inv	ADJ
bptjm-16	283	3	.	.	PUNCT
bptjm-16	284	1	2000	2000	NUM
bptjm-16	284	2	apr	apr	NOUN
bptjm-16	284	3	;	;	PUNCT
bptjm-16	284	4	80(4):471	80(4):471	NOUN
bptjm-16	284	5	-	-	SYM
bptjm-16	284	6	84	84	NUM
bptjm-16	284	7	.	.	PUNCT
bptjm-16	285	1	doi	doi	NOUN
bptjm-16	285	2	:	:	PUNCT
bptjm-16	285	3	10.1038/	10.1038/	NUM
bptjm-16	285	4	labinvest.3780053	labinvest.3780053	PROPN
bptjm-16	285	5	.	.	PROPN
bptjm-16	285	6	19	19	NUM
bptjm-16	285	7	.	.	PUNCT
bptjm-16	286	1	danial	danial	PROPN
bptjm-16	286	2	,	,	PUNCT
bptjm-16	286	3	nn	nn	PROPN
bptjm-16	286	4	&	&	CCONJ
bptjm-16	286	5	korsmeyer	korsmeyer	PROPN
bptjm-16	286	6	,	,	PUNCT
bptjm-16	286	7	sj	sj	PROPN
bptjm-16	286	8	.	.	PROPN
bptjm-16	286	9	cell	cell	NOUN
bptjm-16	286	10	death	death	NOUN
bptjm-16	286	11	:	:	PUNCT
bptjm-16	286	12	critical	critical	ADJ
bptjm-16	286	13	control	control	NOUN
bptjm-16	286	14	points	point	NOUN
bptjm-16	286	15	.	.	PUNCT
bptjm-16	287	1	cell	cell	NOUN
bptjm-16	287	2	.	.	PUNCT
bptjm-16	288	1	2004	2004	NUM
bptjm-16	288	2	jan	jan	PROPN
bptjm-16	288	3	23	23	NUM
bptjm-16	288	4	;	;	PUNCT
bptjm-16	288	5	116(2):205	116(2):205	NUM
bptjm-16	288	6	-	-	SYM
bptjm-16	288	7	19	19	NUM
bptjm-16	288	8	.	.	PUNCT
bptjm-16	288	9	doi:10.1016	doi:10.1016	PROPN
bptjm-16	288	10	/	/	SYM
bptjm-16	288	11	s0092	s0092	PROPN
bptjm-16	288	12	-	-	PUNCT
bptjm-16	288	13	8674(04)00046	8674(04)00046	NUM
bptjm-16	288	14	-	-	SYM
bptjm-16	288	15	7	7	NUM
bptjm-16	288	16	.	.	NOUN
bptjm-16	288	17	20	20	NUM
bptjm-16	288	18	.	.	PUNCT
bptjm-16	289	1	degterev	degterev	PROPN
bptjm-16	289	2	,	,	PUNCT
bptjm-16	289	3	a	a	PRON
bptjm-16	289	4	,	,	PUNCT
bptjm-16	289	5	boyce	boyce	PROPN
bptjm-16	289	6	,	,	PUNCT
bptjm-16	289	7	m	m	PROPN
bptjm-16	289	8	&	&	CCONJ
bptjm-16	289	9	yuan	yuan	PROPN
bptjm-16	289	10	,	,	PUNCT
bptjm-16	289	11	j.	j.	PROPN
bptjm-16	289	12	a	a	DET
bptjm-16	289	13	decade	decade	NOUN
bptjm-16	289	14	of	of	ADP
bptjm-16	289	15	caspases	caspase	NOUN
bptjm-16	289	16	.	.	PUNCT
bptjm-16	290	1	oncogene	oncogene	NOUN
bptjm-16	290	2	.	.	PUNCT
bptjm-16	291	1	2003	2003	NUM
bptjm-16	291	2	nov	nov	NOUN
bptjm-16	291	3	24	24	NUM
bptjm-16	291	4	;	;	PUNCT
bptjm-16	291	5	22(53):8543	22(53):8543	NUM
bptjm-16	291	6	.	.	PUNCT
bptjm-16	291	7	doi	doi	NOUN
bptjm-16	291	8	:	:	PUNCT
bptjm-16	291	9	10.1038	10.1038	NUM
bptjm-16	291	10	/	/	SYM
bptjm-16	291	11	sj.onc.1207107	sj.onc.1207107	PROPN
bptjm-16	291	12	.	.	PUNCT
bptjm-16	292	1	21	21	NUM
bptjm-16	292	2	.	.	PUNCT
bptjm-16	293	1	lockshin	lockshin	PROPN
bptjm-16	293	2	,	,	PUNCT
bptjm-16	293	3	ra	ra	PROPN
bptjm-16	293	4	&	&	CCONJ
bptjm-16	293	5	zakeri	zakeri	PROPN
bptjm-16	293	6	,	,	PUNCT
bptjm-16	293	7	z.	z.	PROPN
bptjm-16	293	8	programmed	program	VERB
bptjm-16	293	9	cell	cell	NOUN
bptjm-16	293	10	death	death	NOUN
bptjm-16	293	11	and	and	CCONJ
bptjm-16	293	12	apoptosis	apoptosis	NOUN
bptjm-16	293	13	:	:	PUNCT
bptjm-16	293	14	origins	origin	NOUN
bptjm-16	293	15	of	of	ADP
bptjm-16	293	16	the	the	DET
bptjm-16	293	17	theory	theory	NOUN
bptjm-16	293	18	.	.	PUNCT
bptjm-16	294	1	nat	nat	PROPN
bptjm-16	294	2	.	.	PUNCT
bptjm-16	295	1	rev	rev	PROPN
bptjm-16	295	2	.	.	PROPN
bptjm-16	295	3	mol	mol	PROPN
bptjm-16	295	4	.	.	PROPN
bptjm-16	295	5	cell	cell	PROPN
bptjm-16	295	6	biol	biol	PROPN
bptjm-16	295	7	.	.	PUNCT
bptjm-16	296	1	2001	2001	NUM
bptjm-16	296	2	jul	jul	NOUN
bptjm-16	296	3	;	;	PUNCT
bptjm-16	296	4	2(7):545	2(7):545	NUM
bptjm-16	296	5	-	-	SYM
bptjm-16	296	6	50	50	NUM
bptjm-16	296	7	.	.	PUNCT
bptjm-16	297	1	doi	doi	NOUN
bptjm-16	297	2	:	:	PUNCT
bptjm-16	297	3	10.1038/35080097	10.1038/35080097	NUM
bptjm-16	297	4	.	.	NOUN
bptjm-16	297	5	22	22	NUM
bptjm-16	297	6	.	.	PUNCT
bptjm-16	298	1	nakagawa	nakagawa	PROPN
bptjm-16	298	2	,	,	PUNCT
bptjm-16	298	3	t	t	PROPN
bptjm-16	298	4	et	et	PROPN
bptjm-16	298	5	al	al	PROPN
bptjm-16	298	6	.	.	PUNCT
bptjm-16	299	1	caspase-12	caspase-12	NOUN
bptjm-16	299	2	mediates	mediate	VERB
bptjm-16	299	3	endoplasmic	endoplasmic	NOUN
bptjm-16	299	4	-	-	PUNCT
bptjm-16	299	5	reticulum	reticulum	NOUN
bptjm-16	299	6	-	-	PUNCT
bptjm-16	299	7	speci	speci	NOUN
bptjm-16	299	8	c	c	NOUN
bptjm-16	299	9	apoptosis	apoptosis	NOUN
bptjm-16	299	10	and	and	CCONJ
bptjm-16	299	11	cytotoxicity	cytotoxicity	NOUN
bptjm-16	299	12	by	by	ADP
bptjm-16	299	13	amyloid	amyloid	NOUN
bptjm-16	299	14	-	-	PUNCT
bptjm-16	299	15	β	β	NOUN
bptjm-16	299	16	.	.	PUNCT
bptjm-16	299	17	nature	nature	NOUN
bptjm-16	299	18	.	.	PUNCT
bptjm-16	300	1	2000	2000	NUM
bptjm-16	300	2	jan	jan	NOUN
bptjm-16	300	3	6	6	NUM
bptjm-16	300	4	;	;	PUNCT
bptjm-16	300	5	403(6765):98	403(6765):98	NUM
bptjm-16	300	6	-	-	SYM
bptjm-16	300	7	103	103	NUM
bptjm-16	300	8	.	.	PUNCT
bptjm-16	301	1	doi	doi	NOUN
bptjm-16	301	2	:	:	PUNCT
bptjm-16	301	3	10.1038/47513	10.1038/47513	NUM
bptjm-16	301	4	.	.	NOUN
bptjm-16	302	1	23	23	NUM
bptjm-16	302	2	.	.	PUNCT
bptjm-16	303	1	duprez	duprez	PROPN
bptjm-16	303	2	,	,	PUNCT
bptjm-16	303	3	l	l	NOUN
bptjm-16	303	4	,	,	PUNCT
bptjm-16	303	5	wirawan	wirawan	NOUN
bptjm-16	303	6	,	,	PUNCT
bptjm-16	303	7	e	e	NOUN
bptjm-16	303	8	,	,	PUNCT
bptjm-16	303	9	berghe	berghe	NOUN
bptjm-16	303	10	,	,	PUNCT
bptjm-16	303	11	tv	tv	NOUN
bptjm-16	303	12	&	&	CCONJ
bptjm-16	303	13	vandenabeele	vandenabeele	PROPN
bptjm-16	303	14	,	,	PUNCT
bptjm-16	303	15	p.	p.	NOUN
bptjm-16	303	16	major	major	ADJ
bptjm-16	303	17	cell	cell	NOUN
bptjm-16	303	18	death	death	NOUN
bptjm-16	303	19	pathways	pathway	NOUN
bptjm-16	303	20	at	at	ADP
bptjm-16	303	21	a	a	DET
bptjm-16	303	22	glance	glance	NOUN
bptjm-16	303	23	.	.	PUNCT
bptjm-16	304	1	microbes	microbe	NOUN
bptjm-16	304	2	infect	infect	VERB
bptjm-16	304	3	.	.	PUNCT
bptjm-16	305	1	2009	2009	NUM
bptjm-16	305	2	nov	nov	NOUN
bptjm-16	305	3	;	;	PUNCT
bptjm-16	305	4	11(13):1050	11(13):1050	NUM
bptjm-16	305	5	-	-	SYM
bptjm-16	305	6	62	62	NUM
bptjm-16	305	7	.	.	PUNCT
bptjm-16	306	1	doi	doi	NOUN
bptjm-16	306	2	:	:	PUNCT
bptjm-16	306	3	10.1016	10.1016	NUM
bptjm-16	306	4	/	/	SYM
bptjm-16	306	5	j.micinf.2009.08.013	j.micinf.2009.08.013	PROPN
bptjm-16	306	6	.	.	PROPN
bptjm-16	306	7	24	24	NUM
bptjm-16	306	8	.	.	PUNCT
bptjm-16	307	1	gallucci	gallucci	PROPN
bptjm-16	307	2	s	s	PROPN
bptjm-16	307	3	,	,	PUNCT
bptjm-16	307	4	caricchio	caricchio	ADJ
bptjm-16	307	5	r	r	NOUN
bptjm-16	307	6	,	,	PUNCT
bptjm-16	307	7	cohen	cohen	PROPN
bptjm-16	307	8	p.	p.	PROPN
bptjm-16	307	9	chapter	chapter	NOUN
bptjm-16	307	10	16	16	NUM
bptjm-16	307	11	cell	cell	NOUN
bptjm-16	307	12	death	death	NOUN
bptjm-16	307	13	and	and	CCONJ
bptjm-16	307	14	autoimmune	autoimmune	ADJ
bptjm-16	307	15	disease	disease	NOUN
bptjm-16	307	16	.	.	PUNCT
bptjm-16	308	1	theautoimmune	theautoimmune	ADJ
bptjm-16	308	2	diseases	disease	NOUN
bptjm-16	308	3	.	.	PUNCT
bptjm-16	309	1	6th	6th	ADJ
bptjm-16	309	2	ed	ed	NOUN
bptjm-16	309	3	.	.	PROPN
bptjm-16	309	4	,	,	PUNCT
bptjm-16	309	5	academic	academic	ADJ
bptjm-16	309	6	press	press	NOUN
bptjm-16	309	7	.	.	PUNCT
bptjm-16	310	1	2020	2020	NUM
bptjm-16	310	2	;	;	PUNCT
bptjm-16	310	3	291	291	NUM
bptjm-16	310	4	-	-	SYM
bptjm-16	310	5	303	303	NUM
bptjm-16	310	6	.	.	PUNCT
bptjm-16	311	1	https://doi.org/10.1016/b978-0-12-812102-3.00016-6	https://doi.org/10.1016/b978-0-12-812102-3.00016-6	PROPN
bptjm-16	311	2	25	25	NUM
bptjm-16	311	3	.	.	PUNCT
bptjm-16	312	1	wang	wang	PROPN
bptjm-16	312	2	,	,	PUNCT
bptjm-16	312	3	y	y	PROPN
bptjm-16	312	4	&	&	CCONJ
bptjm-16	312	5	tjandra	tjandra	PROPN
bptjm-16	312	6	,	,	PUNCT
bptjm-16	312	7	n.	n.	ADJ
bptjm-16	312	8	structural	structural	ADJ
bptjm-16	312	9	insights	insight	NOUN
bptjm-16	312	10	of	of	ADP
bptjm-16	312	11	tbid	tbid	ADJ
bptjm-16	312	12	,	,	PUNCT
bptjm-16	312	13	the	the	DET
bptjm-16	312	14	caspase-8	caspase-8	NOUN
bptjm-16	312	15	-	-	PUNCT
bptjm-16	312	16	activated	activate	VERB
bptjm-16	312	17	bid	bid	NOUN
bptjm-16	312	18	,	,	PUNCT
bptjm-16	312	19	and	and	CCONJ
bptjm-16	312	20	its	its	PRON
bptjm-16	312	21	bh3	bh3	ADJ
bptjm-16	312	22	domain	domain	NOUN
bptjm-16	312	23	.	.	PUNCT
bptjm-16	313	1	j.	j.	PROPN
bptjm-16	313	2	biol	biol	PROPN
bptjm-16	313	3	.	.	PUNCT
bptjm-16	314	1	chem	chem	PROPN
bptjm-16	314	2	.	.	PUNCT
bptjm-16	315	1	2013	2013	NUM
bptjm-16	315	2	dec	dec	PROPN
bptjm-16	315	3	13	13	NUM
bptjm-16	315	4	;	;	PUNCT
bptjm-16	316	1	288(50):35840	288(50):35840	NUM
bptjm-16	316	2	-	-	SYM
bptjm-16	316	3	51	51	NUM
bptjm-16	316	4	.	.	PUNCT
bptjm-16	317	1	doi	doi	NOUN
bptjm-16	317	2	:	:	PUNCT
bptjm-16	317	3	10.1074	10.1074	NUM
bptjm-16	317	4	/	/	SYM
bptjm-16	317	5	jbc.m113.503680	jbc.m113.503680	NOUN
bptjm-16	317	6	.	.	PUNCT
bptjm-16	318	1	epub	epub	PROPN
bptjm-16	318	2	2013	2013	NUM
bptjm-16	318	3	oct	oct	NOUN
bptjm-16	318	4	24	24	NUM
bptjm-16	318	5	.	.	PROPN
bptjm-16	318	6	26	26	NUM
bptjm-16	318	7	.	.	PUNCT
bptjm-16	319	1	fan	fan	PROPN
bptjm-16	319	2	,	,	PUNCT
bptjm-16	319	3	tj	tj	PROPN
bptjm-16	319	4	,	,	PUNCT
bptjm-16	319	5	han	han	PROPN
bptjm-16	319	6	,	,	PUNCT
bptjm-16	319	7	lh	lh	PROPN
bptjm-16	319	8	,	,	PUNCT
bptjm-16	319	9	cong	cong	PROPN
bptjm-16	319	10	,	,	PUNCT
bptjm-16	319	11	rs	rs	PROPN
bptjm-16	319	12	&	&	CCONJ
bptjm-16	319	13	liang	liang	PROPN
bptjm-16	319	14	,	,	PUNCT
bptjm-16	320	1	j.	j.	PROPN
bptjm-16	320	2	caspase	caspase	PROPN
bptjm-16	320	3	family	family	NOUN
bptjm-16	320	4	proteases	protease	NOUN
bptjm-16	320	5	and	and	CCONJ
bptjm-16	320	6	apoptosis	apoptosis	NOUN
bptjm-16	320	7	.	.	PUNCT
bptjm-16	321	1	acta	acta	PROPN
bptjm-16	321	2	biochem	biochem	PROPN
bptjm-16	321	3	.	.	PUNCT
bptjm-16	322	1	biophys	biophy	NOUN
bptjm-16	322	2	.	.	PUNCT
bptjm-16	323	1	sin	sin	NOUN
bptjm-16	323	2	.	.	PUNCT
bptjm-16	324	1	2005	2005	NUM
bptjm-16	324	2	nov	nov	NOUN
bptjm-16	324	3	;	;	PUNCT
bptjm-16	324	4	37(11):719	37(11):719	NUM
bptjm-16	324	5	-	-	SYM
bptjm-16	324	6	27	27	NUM
bptjm-16	324	7	.	.	PUNCT
bptjm-16	325	1	doi	doi	NOUN
bptjm-16	325	2	:	:	PUNCT
bptjm-16	325	3	10.1111	10.1111	NUM
bptjm-16	325	4	/	/	SYM
bptjm-16	325	5	j.1745	j.1745	NOUN
bptjm-16	325	6	-	-	PUNCT
bptjm-16	325	7	7270.2005.00108.x	7270.2005.00108.x	NOUN
bptjm-16	325	8	.	.	PUNCT
bptjm-16	326	1	27	27	NUM
bptjm-16	326	2	.	.	PUNCT
bptjm-16	327	1	favaloro	favaloro	PROPN
bptjm-16	327	2	,	,	PUNCT
bptjm-16	327	3	b	b	NOUN
bptjm-16	327	4	,	,	PUNCT
bptjm-16	327	5	allocati	allocati	PROPN
bptjm-16	327	6	,	,	PUNCT
bptjm-16	327	7	n	n	CCONJ
bptjm-16	327	8	,	,	PUNCT
bptjm-16	327	9	graziano	graziano	PROPN
bptjm-16	327	10	,	,	PUNCT
bptjm-16	327	11	v	v	PROPN
bptjm-16	327	12	,	,	PUNCT
bptjm-16	327	13	di	di	NOUN
bptjm-16	327	14	ilio	ilio	NOUN
bptjm-16	327	15	,	,	PUNCT
bptjm-16	327	16	c	c	PROPN
bptjm-16	327	17	&	&	CCONJ
bptjm-16	327	18	de	de	X
bptjm-16	327	19	laurenzi	laurenzi	PROPN
bptjm-16	327	20	,	,	PUNCT
bptjm-16	327	21	v.	v.	ADP
bptjm-16	327	22	role	role	NOUN
bptjm-16	327	23	of	of	ADP
bptjm-16	327	24	apoptosis	apoptosis	NOUN
bptjm-16	327	25	in	in	ADP
bptjm-16	327	26	disease	disease	NOUN
bptjm-16	327	27	.	.	PUNCT
bptjm-16	328	1	berkeley	berkeley	PROPN
bptjm-16	328	2	pharma	pharma	PROPN
bptjm-16	328	3	tech	tech	PROPN
bptjm-16	328	4	journal	journal	NOUN
bptjm-16	328	5	of	of	ADP
bptjm-16	328	6	medicine	medicine	NOUN
bptjm-16	328	7	|	|	ADV
bptjm-16	328	8	111	111	NUM
bptjm-16	328	9	aging	aging	NOUN
bptjm-16	328	10	.	.	PUNCT
bptjm-16	329	1	2012	2012	NUM
bptjm-16	329	2	may	may	AUX
bptjm-16	329	3	;	;	PUNCT
bptjm-16	329	4	4(5):330	4(5):330	NUM
bptjm-16	329	5	-	-	SYM
bptjm-16	329	6	49	49	NUM
bptjm-16	329	7	.	.	PUNCT
bptjm-16	330	1	doi	doi	NOUN
bptjm-16	330	2	:	:	PUNCT
bptjm-16	330	3	10.18632	10.18632	NUM
bptjm-16	330	4	/	/	SYM
bptjm-16	330	5	aging.100459	aging.100459	NOUN
bptjm-16	330	6	.	.	PROPN
bptjm-16	330	7	28	28	NUM
bptjm-16	330	8	.	.	PUNCT
bptjm-16	331	1	mcilwain	mcilwain	PROPN
bptjm-16	331	2	,	,	PUNCT
bptjm-16	331	3	dr	dr	PROPN
bptjm-16	331	4	,	,	PUNCT
bptjm-16	331	5	berger	berger	PROPN
bptjm-16	331	6	,	,	PUNCT
bptjm-16	331	7	t	t	PROPN
bptjm-16	331	8	&	&	CCONJ
bptjm-16	331	9	mak	mak	PROPN
bptjm-16	331	10	,	,	PUNCT
bptjm-16	331	11	tw	tw	PROPN
bptjm-16	331	12	.	.	PUNCT
bptjm-16	332	1	caspase	caspase	NOUN
bptjm-16	332	2	functions	function	NOUN
bptjm-16	332	3	in	in	ADP
bptjm-16	332	4	cell	cell	NOUN
bptjm-16	332	5	death	death	NOUN
bptjm-16	332	6	and	and	CCONJ
bptjm-16	332	7	disease	disease	NOUN
bptjm-16	332	8	.	.	PUNCT
bptjm-16	333	1	cold	cold	ADJ
bptjm-16	333	2	spring	spring	NOUN
bptjm-16	333	3	harb	harb	PROPN
bptjm-16	333	4	.	.	PUNCT
bptjm-16	334	1	perspect	perspect	VERB
bptjm-16	334	2	.	.	PUNCT
bptjm-16	335	1	2013	2013	NUM
bptjm-16	335	2	apr	apr	NOUN
bptjm-16	335	3	1	1	NUM
bptjm-16	335	4	;	;	PUNCT
bptjm-16	335	5	5(4):a008656	5(4):a008656	X
bptjm-16	335	6	.	.	PUNCT
bptjm-16	335	7	doi	doi	NOUN
bptjm-16	335	8	:	:	PUNCT
bptjm-16	335	9	10.1101	10.1101	NUM
bptjm-16	335	10	/	/	SYM
bptjm-16	335	11	cshperspect.a008656	cshperspect.a008656	NOUN
bptjm-16	335	12	.	.	PUNCT
bptjm-16	336	1	29	29	NUM
bptjm-16	336	2	.	.	X
bptjm-16	337	1	gross	gross	ADJ
bptjm-16	337	2	,	,	PUNCT
bptjm-16	337	3	a	a	PRON
bptjm-16	337	4	,	,	PUNCT
bptjm-16	337	5	mcdonnell	mcdonnell	PROPN
bptjm-16	337	6	,	,	PUNCT
bptjm-16	337	7	jm	jm	PROPN
bptjm-16	337	8	&	&	CCONJ
bptjm-16	337	9	korsmeyer	korsmeyer	PROPN
bptjm-16	337	10	,	,	PUNCT
bptjm-16	337	11	sj	sj	PROPN
bptjm-16	337	12	.	.	PUNCT
bptjm-16	337	13	bcl-2	bcl-2	VERB
bptjm-16	337	14	family	family	NOUN
bptjm-16	337	15	members	member	NOUN
bptjm-16	337	16	and	and	CCONJ
bptjm-16	337	17	the	the	DET
bptjm-16	337	18	mitochondria	mitochondria	NOUN
bptjm-16	337	19	in	in	ADP
bptjm-16	337	20	apoptosis	apoptosis	NOUN
bptjm-16	337	21	.	.	PUNCT
bptjm-16	338	1	genes	gene	NOUN
bptjm-16	338	2	dev	dev	PROPN
bptjm-16	338	3	.	.	PROPN
bptjm-16	338	4	1999	1999	NUM
bptjm-16	338	5	aug	aug	PROPN
bptjm-16	338	6	1	1	NUM
bptjm-16	338	7	;	;	PUNCT
bptjm-16	338	8	13(15):1899	13(15):1899	NUM
bptjm-16	338	9	-	-	SYM
bptjm-16	338	10	911	911	NUM
bptjm-16	338	11	.	.	PUNCT
bptjm-16	339	1	doi	doi	NOUN
bptjm-16	339	2	:	:	PUNCT
bptjm-16	339	3	10.1101	10.1101	NUM
bptjm-16	339	4	/	/	SYM
bptjm-16	339	5	gad.13.15.1899	gad.13.15.1899	NOUN
bptjm-16	339	6	.	.	PUNCT
bptjm-16	340	1	30	30	NUM
bptjm-16	340	2	.	.	PUNCT
bptjm-16	341	1	ozören	ozören	NOUN
bptjm-16	341	2	,	,	PUNCT
bptjm-16	341	3	n	n	PROPN
bptjm-16	341	4	&	&	CCONJ
bptjm-16	341	5	el	el	PROPN
bptjm-16	341	6	-	-	PUNCT
bptjm-16	341	7	deiry	deiry	PROPN
bptjm-16	341	8	,	,	PUNCT
bptjm-16	341	9	ws	ws	NOUN
bptjm-16	341	10	.	.	PUNCT
bptjm-16	341	11	de	de	X
bptjm-16	341	12	ning	ning	PROPN
bptjm-16	341	13	characteristics	characteristic	NOUN
bptjm-16	341	14	of	of	ADP
bptjm-16	341	15	types	type	NOUN
bptjm-16	342	1	i	i	PRON
bptjm-16	342	2	and	and	CCONJ
bptjm-16	342	3	ii	ii	PROPN
bptjm-16	342	4	apoptotic	apoptotic	ADJ
bptjm-16	342	5	cells	cell	NOUN
bptjm-16	342	6	in	in	ADP
bptjm-16	342	7	response	response	NOUN
bptjm-16	342	8	to	to	ADP
bptjm-16	342	9	trail	trail	NOUN
bptjm-16	342	10	.	.	PUNCT
bptjm-16	343	1	neoplasia	neoplasia	NOUN
bptjm-16	343	2	.	.	PUNCT
bptjm-16	344	1	nov	nov	PROPN
bptjm-16	344	2	-	-	PROPN
bptjm-16	344	3	dec	dec	PROPN
bptjm-16	344	4	2002	2002	NUM
bptjm-16	344	5	;	;	PUNCT
bptjm-16	344	6	4(6):551	4(6):551	NUM
bptjm-16	344	7	-	-	SYM
bptjm-16	344	8	7	7	NUM
bptjm-16	344	9	.	.	PUNCT
bptjm-16	344	10	doi	doi	NOUN
bptjm-16	344	11	:	:	PUNCT
bptjm-16	344	12	10.1038	10.1038	NUM
bptjm-16	344	13	/	/	SYM
bptjm-16	344	14	sj.neo.7900270	sj.neo.7900270	PROPN
bptjm-16	344	15	.	.	PROPN
bptjm-16	344	16	31	31	NUM
bptjm-16	344	17	.	.	PUNCT
bptjm-16	345	1	ricci	ricci	PROPN
bptjm-16	345	2	,	,	PUNCT
bptjm-16	345	3	je	je	PROPN
bptjm-16	345	4	et	et	PROPN
bptjm-16	345	5	al	al	PROPN
bptjm-16	345	6	.	.	PUNCT
bptjm-16	345	7	disruption	disruption	NOUN
bptjm-16	345	8	of	of	ADP
bptjm-16	345	9	mitochondrial	mitochondrial	ADJ
bptjm-16	345	10	function	function	NOUN
bptjm-16	345	11	during	during	ADP
bptjm-16	345	12	apoptosis	apoptosis	NOUN
bptjm-16	345	13	is	be	AUX
bptjm-16	345	14	mediated	mediate	VERB
bptjm-16	345	15	by	by	ADP
bptjm-16	345	16	caspase	caspase	NOUN
bptjm-16	345	17	cleavage	cleavage	NOUN
bptjm-16	345	18	of	of	ADP
bptjm-16	345	19	the	the	DET
bptjm-16	345	20	p75	p75	ADJ
bptjm-16	345	21	subunit	subunit	NOUN
bptjm-16	345	22	of	of	ADP
bptjm-16	345	23	complex	complex	ADJ
bptjm-16	345	24	i	i	PRON
bptjm-16	345	25	of	of	ADP
bptjm-16	345	26	the	the	DET
bptjm-16	345	27	electron	electron	NOUN
bptjm-16	345	28	transport	transport	NOUN
bptjm-16	345	29	chain	chain	NOUN
bptjm-16	345	30	.	.	PUNCT
bptjm-16	346	1	cell	cell	NOUN
bptjm-16	346	2	.	.	PUNCT
bptjm-16	347	1	2004	2004	NUM
bptjm-16	347	2	jun	jun	PROPN
bptjm-16	347	3	11	11	NUM
bptjm-16	347	4	;	;	PUNCT
bptjm-16	347	5	117(6):773	117(6):773	NUM
bptjm-16	347	6	-	-	SYM
bptjm-16	347	7	86	86	NUM
bptjm-16	347	8	.	.	PUNCT
bptjm-16	348	1	doi	doi	NOUN
bptjm-16	348	2	:	:	PUNCT
bptjm-16	348	3	10.1016	10.1016	NUM
bptjm-16	348	4	/	/	SYM
bptjm-16	348	5	j.cell.2004.05.008	j.cell.2004.05.008	NOUN
bptjm-16	348	6	.	.	PUNCT
bptjm-16	349	1	32	32	NUM
bptjm-16	349	2	.	.	PUNCT
bptjm-16	349	3	soldani	soldani	NOUN
bptjm-16	349	4	,	,	PUNCT
bptjm-16	350	1	c	c	PROPN
bptjm-16	350	2	et	et	PROPN
bptjm-16	350	3	al	al	PROPN
bptjm-16	350	4	.	.	PROPN
bptjm-16	350	5	poly	poly	PROPN
bptjm-16	350	6	(	(	PUNCT
bptjm-16	350	7	adp	adp	PROPN
bptjm-16	350	8	-	-	PUNCT
bptjm-16	350	9	ribose	ribose	NOUN
bptjm-16	350	10	)	)	PUNCT
bptjm-16	350	11	polymerase	polymerase	NOUN
bptjm-16	350	12	cleavage	cleavage	NOUN
bptjm-16	350	13	during	during	ADP
bptjm-16	350	14	apoptosis	apoptosis	NOUN
bptjm-16	350	15	:	:	PUNCT
bptjm-16	350	16	when	when	SCONJ
bptjm-16	350	17	and	and	CCONJ
bptjm-16	350	18	where	where	SCONJ
bptjm-16	350	19	?	?	PUNCT
bptjm-16	351	1	exp	exp	NOUN
bptjm-16	351	2	.	.	PUNCT
bptjm-16	351	3	cell	cell	NOUN
bptjm-16	351	4	res	re	NOUN
bptjm-16	351	5	.	.	PUNCT
bptjm-16	352	1	2001	2001	NUM
bptjm-16	352	2	oct	oct	NOUN
bptjm-16	352	3	1	1	NUM
bptjm-16	352	4	;	;	PUNCT
bptjm-16	352	5	269(2):193	269(2):193	NUM
bptjm-16	352	6	-	-	NUM
bptjm-16	352	7	201	201	NUM
bptjm-16	352	8	.	.	PUNCT
bptjm-16	353	1	doi	doi	NOUN
bptjm-16	353	2	:	:	PUNCT
bptjm-16	353	3	10.1006	10.1006	NUM
bptjm-16	353	4	/	/	SYM
bptjm-16	353	5	excr.2001.5293	excr.2001.5293	NOUN
bptjm-16	353	6	.	.	PROPN
bptjm-16	354	1	33	33	NUM
bptjm-16	354	2	.	.	PUNCT
bptjm-16	355	1	yuan	yuan	PROPN
bptjm-16	355	2	,	,	PUNCT
bptjm-16	355	3	s	s	PROPN
bptjm-16	355	4	&	&	CCONJ
bptjm-16	355	5	akey	akey	PROPN
bptjm-16	355	6	,	,	PUNCT
bptjm-16	355	7	cw	cw	PROPN
bptjm-16	355	8	.	.	PROPN
bptjm-16	355	9	apoptosome	apoptosome	PROPN
bptjm-16	355	10	structure	structure	NOUN
bptjm-16	355	11	,	,	PUNCT
bptjm-16	355	12	assembly	assembly	NOUN
bptjm-16	355	13	,	,	PUNCT
bptjm-16	355	14	and	and	CCONJ
bptjm-16	355	15	procaspase	procaspase	NOUN
bptjm-16	355	16	activation	activation	NOUN
bptjm-16	355	17	.	.	PUNCT
bptjm-16	356	1	structure	structure	NOUN
bptjm-16	356	2	.	.	PUNCT
bptjm-16	357	1	2013	2013	NUM
bptjm-16	357	2	apr	apr	NOUN
bptjm-16	357	3	2	2	NUM
bptjm-16	357	4	;	;	PUNCT
bptjm-16	357	5	21(4):501	21(4):501	NOUN
bptjm-16	357	6	-	-	SYM
bptjm-16	357	7	15	15	NUM
bptjm-16	357	8	.	.	PUNCT
bptjm-16	357	9	doi	doi	NOUN
bptjm-16	357	10	:	:	PUNCT
bptjm-16	357	11	10.1016	10.1016	NUM
bptjm-16	357	12	/	/	SYM
bptjm-16	357	13	j.str.2013.02.024	j.str.2013.02.024	PROPN
bptjm-16	357	14	.	.	PUNCT
bptjm-16	358	1	34	34	NUM
bptjm-16	358	2	.	.	PUNCT
bptjm-16	358	3	morishima	morishima	PROPN
bptjm-16	358	4	,	,	PUNCT
bptjm-16	358	5	n	n	CCONJ
bptjm-16	358	6	,	,	PUNCT
bptjm-16	358	7	nakanishi	nakanishi	PROPN
bptjm-16	358	8	,	,	PUNCT
bptjm-16	358	9	k	k	PROPN
bptjm-16	358	10	,	,	PUNCT
bptjm-16	358	11	takenouchi	takenouchi	INTJ
bptjm-16	358	12	,	,	PUNCT
bptjm-16	358	13	h	h	PROPN
bptjm-16	358	14	,	,	PUNCT
bptjm-16	358	15	shibata	shibata	PROPN
bptjm-16	358	16	,	,	PUNCT
bptjm-16	358	17	t	t	PROPN
bptjm-16	358	18	&	&	CCONJ
bptjm-16	358	19	yasuhiko	yasuhiko	PROPN
bptjm-16	358	20	,	,	PUNCT
bptjm-16	358	21	y.	y.	NOUN
bptjm-16	358	22	an	an	DET
bptjm-16	358	23	endoplasmic	endoplasmic	ADJ
bptjm-16	358	24	reticulum	reticulum	NOUN
bptjm-16	358	25	stress	stress	NOUN
bptjm-16	358	26	-	-	PUNCT
bptjm-16	358	27	speci	speci	ADJ
bptjm-16	358	28	c	c	PROPN
bptjm-16	358	29	caspase	caspase	PROPN
bptjm-16	358	30	cascade	cascade	NOUN
bptjm-16	358	31	in	in	ADP
bptjm-16	358	32	apoptosis	apoptosis	NOUN
bptjm-16	358	33	cytochrome	cytochrome	NOUN
bptjm-16	358	34	c	c	NOUN
bptjm-16	358	35	-	-	PUNCT
bptjm-16	358	36	independent	independent	ADJ
bptjm-16	358	37	activation	activation	NOUN
bptjm-16	358	38	of	of	ADP
bptjm-16	358	39	caspase-9	caspase-9	NUM
bptjm-16	358	40	by	by	ADP
bptjm-16	358	41	caspase-12	caspase-12	PROPN
bptjm-16	358	42	.	.	PUNCT
bptjm-16	358	43	j.	j.	PROPN
bptjm-16	358	44	biol	biol	PROPN
bptjm-16	358	45	.	.	PUNCT
bptjm-16	359	1	chem	chem	PROPN
bptjm-16	359	2	.	.	PUNCT
bptjm-16	360	1	2002	2002	NUM
bptjm-16	360	2	sep	sep	PROPN
bptjm-16	360	3	13	13	NUM
bptjm-16	360	4	;	;	PUNCT
bptjm-16	360	5	277(37):34287	277(37):34287	PROPN
bptjm-16	360	6	-	-	SYM
bptjm-16	360	7	94	94	NUM
bptjm-16	360	8	.	.	PUNCT
bptjm-16	361	1	doi	doi	NOUN
bptjm-16	361	2	:	:	PUNCT
bptjm-16	361	3	10.1074	10.1074	NUM
bptjm-16	361	4	/	/	SYM
bptjm-16	361	5	jbc.m204973200	jbc.m204973200	X
bptjm-16	361	6	.	.	PUNCT
bptjm-16	362	1	epub	epub	PROPN
bptjm-16	362	2	2002	2002	NUM
bptjm-16	362	3	jul	jul	PROPN
bptjm-16	362	4	3	3	NUM
bptjm-16	362	5	.	.	PROPN
bptjm-16	362	6	35	35	NUM
bptjm-16	362	7	.	.	PUNCT
bptjm-16	363	1	tan	tan	PROPN
bptjm-16	363	2	,	,	PUNCT
bptjm-16	363	3	y	y	PROPN
bptjm-16	363	4	et	et	PROPN
bptjm-16	363	5	al	al	PROPN
bptjm-16	363	6	.	.	PROPN
bptjm-16	364	1	ubiquitous	ubiquitous	ADJ
bptjm-16	364	2	calpains	calpain	NOUN
bptjm-16	364	3	promote	promote	VERB
bptjm-16	364	4	caspase-12	caspase-12	PROPN
bptjm-16	364	5	and	and	CCONJ
bptjm-16	364	6	jnk	jnk	PROPN
bptjm-16	364	7	activation	activation	NOUN
bptjm-16	364	8	during	during	ADP
bptjm-16	364	9	endoplasmic	endoplasmic	ADJ
bptjm-16	364	10	reticulum	reticulum	NOUN
bptjm-16	364	11	stress	stress	NOUN
bptjm-16	364	12	-	-	PUNCT
bptjm-16	364	13	induced	induce	VERB
bptjm-16	364	14	apoptosis	apoptosis	NOUN
bptjm-16	364	15	.	.	PUNCT
bptjm-16	365	1	j.	j.	PROPN
bptjm-16	365	2	biol	biol	PROPN
bptjm-16	365	3	.	.	PUNCT
bptjm-16	366	1	chem	chem	PROPN
bptjm-16	366	2	.	.	PUNCT
bptjm-16	367	1	2006	2006	NUM
bptjm-16	367	2	jun	jun	PROPN
bptjm-16	367	3	9	9	NUM
bptjm-16	367	4	;	;	PUNCT
bptjm-16	367	5	281(23):16016	281(23):16016	PROPN
bptjm-16	367	6	-	-	SYM
bptjm-16	367	7	24	24	NUM
bptjm-16	367	8	.	.	PUNCT
bptjm-16	367	9	doi	doi	NOUN
bptjm-16	367	10	:	:	PUNCT
bptjm-16	367	11	10.1074	10.1074	NUM
bptjm-16	367	12	/	/	SYM
bptjm-16	367	13	jbc.m601299200	jbc.m601299200	PROPN
bptjm-16	367	14	.	.	PUNCT
bptjm-16	368	1	epub	epub	PROPN
bptjm-16	368	2	2006	2006	NUM
bptjm-16	368	3	apr	apr	NOUN
bptjm-16	368	4	5	5	NUM
bptjm-16	368	5	.	.	SYM
bptjm-16	368	6	36	36	NUM
bptjm-16	368	7	.	.	X
bptjm-16	368	8	ameison	ameison	PROPN
bptjm-16	368	9	jc	jc	PROPN
bptjm-16	368	10	,	,	PUNCT
bptjm-16	368	11	capron	capron	NOUN
bptjm-16	368	12	a.	a.	NOUN
bptjm-16	368	13	cell	cell	NOUN
bptjm-16	368	14	dysfunction	dysfunction	NOUN
bptjm-16	368	15	and	and	CCONJ
bptjm-16	368	16	depletion	depletion	NOUN
bptjm-16	368	17	in	in	ADP
bptjm-16	368	18	aids	aids	PROPN
bptjm-16	368	19	:	:	PUNCT
bptjm-16	368	20	the	the	DET
bptjm-16	368	21	programmed	program	VERB
bptjm-16	368	22	cell	cell	NOUN
bptjm-16	368	23	death	death	NOUN
bptjm-16	368	24	hypothesis	hypothesis	NOUN
bptjm-16	368	25	.	.	PUNCT
bptjm-16	369	1	immunol	immunol	NOUN
bptjm-16	369	2	today	today	NOUN
bptjm-16	369	3	.	.	PUNCT
bptjm-16	369	4	1991	1991	NUM
bptjm-16	369	5	apr;12(4):102	apr;12(4):102	NOUN
bptjm-16	369	6	-	-	SYM
bptjm-16	369	7	5	5	NUM
bptjm-16	369	8	.	.	PUNCT
bptjm-16	370	1	doi	doi	NOUN
bptjm-16	370	2	:	:	PUNCT
bptjm-16	370	3	10.1016/0167	10.1016/0167	NUM
bptjm-16	370	4	-	-	PUNCT
bptjm-16	370	5	5699(91)90092	5699(91)90092	NUM
bptjm-16	370	6	-	-	SYM
bptjm-16	370	7	8	8	NUM
bptjm-16	370	8	.	.	PUNCT
bptjm-16	370	9	37	37	NUM
bptjm-16	370	10	.	.	PUNCT
bptjm-16	371	1	walkinshaw	walkinshaw	PROPN
bptjm-16	371	2	g	g	PROPN
bptjm-16	371	3	,	,	PUNCT
bptjm-16	371	4	waters	water	VERB
bptjm-16	371	5	cm	cm	NOUN
bptjm-16	371	6	.	.	PUNCT
bptjm-16	372	1	induction	induction	NOUN
bptjm-16	372	2	of	of	ADP
bptjm-16	372	3	apoptosis	apoptosis	NOUN
bptjm-16	372	4	in	in	ADP
bptjm-16	372	5	catecholaminergic	catecholaminergic	ADJ
bptjm-16	372	6	pc12	pc12	PROPN
bptjm-16	372	7	cells	cell	NOUN
bptjm-16	372	8	by	by	ADP
bptjm-16	372	9	ldopa	ldopa	ADJ
bptjm-16	372	10	.	.	PUNCT
bptjm-16	373	1	implications	implication	NOUN
bptjm-16	373	2	for	for	ADP
bptjm-16	373	3	the	the	DET
bptjm-16	373	4	treatment	treatment	NOUN
bptjm-16	373	5	of	of	ADP
bptjm-16	373	6	parkinson	parkinson	NOUN
bptjm-16	373	7	's	's	PART
bptjm-16	373	8	disease	disease	NOUN
bptjm-16	373	9	.	.	PUNCT
bptjm-16	374	1	j	j	PROPN
bptjm-16	374	2	clin	clin	PROPN
bptjm-16	374	3	invest	invest	PROPN
bptjm-16	374	4	.	.	PUNCT
bptjm-16	375	1	1995	1995	NUM
bptjm-16	375	2	jun	jun	PROPN
bptjm-16	375	3	;	;	PUNCT
bptjm-16	375	4	95(6):2458	95(6):2458	NUM
bptjm-16	375	5	-	-	SYM
bptjm-16	375	6	64	64	NUM
bptjm-16	375	7	.	.	PUNCT
bptjm-16	376	1	doi	doi	NOUN
bptjm-16	376	2	:	:	PUNCT
bptjm-16	376	3	10.1172	10.1172	NUM
bptjm-16	376	4	/	/	SYM
bptjm-16	376	5	jci117946	jci117946	NOUN
bptjm-16	376	6	.	.	PUNCT
bptjm-16	377	1	38	38	NUM
bptjm-16	377	2	.	.	PUNCT
bptjm-16	378	1	land	land	PROPN
bptjm-16	378	2	eld	eld	PROPN
bptjm-16	378	3	pw	pw	PROPN
bptjm-16	378	4	,	,	PUNCT
bptjm-16	378	5	thibault	thibault	PROPN
bptjm-16	378	6	,	,	PUNCT
bptjm-16	378	7	o	o	NOUN
bptjm-16	378	8	,	,	PUNCT
bptjm-16	378	9	mazzanti	mazzanti	ADJ
bptjm-16	378	10	ml	ml	NOUN
bptjm-16	378	11	,	,	PUNCT
bptjm-16	378	12	porter	porter	PROPN
bptjm-16	378	13	nm	nm	PROPN
bptjm-16	378	14	,	,	PUNCT
bptjm-16	378	15	kerr	kerr	PROPN
bptjm-16	378	16	,	,	PUNCT
bptjm-16	378	17	ds	ds	PROPN
bptjm-16	378	18	.	.	PROPN
bptjm-16	378	19	1992	1992	NUM
bptjm-16	378	20	.	.	PUNCT
bptjm-16	379	1	mechanisms	mechanism	NOUN
bptjm-16	379	2	of	of	ADP
bptjm-16	379	3	neuronal	neuronal	ADJ
bptjm-16	379	4	death	death	NOUN
bptjm-16	379	5	in	in	ADP
bptjm-16	379	6	brain	brain	NOUN
bptjm-16	379	7	aging	aging	NOUN
bptjm-16	379	8	and	and	CCONJ
bptjm-16	379	9	alzheimer	alzheimer	PROPN
bptjm-16	379	10	's	's	PART
bptjm-16	379	11	disease	disease	NOUN
bptjm-16	379	12	;	;	PUNCT
bptjm-16	379	13	role	role	NOUN
bptjm-16	379	14	of	of	ADP
bptjm-16	379	15	endocrine	endocrine	NOUN
bptjm-16	379	16	-	-	PUNCT
bptjm-16	379	17	mediated	mediate	VERB
bptjm-16	379	18	calcium	calcium	NOUN
bptjm-16	379	19	dyshomeostasis	dyshomeostasis	NOUN
bptjm-16	379	20	.	.	PUNCT
bptjm-16	380	1	j	j	PROPN
bptjm-16	380	2	neurobiol	neurobiol	PROPN
bptjm-16	380	3	.	.	PUNCT
bptjm-16	381	1	1992	1992	NUM
bptjm-16	381	2	nov	nov	PROPN
bptjm-16	381	3	23(9):1247	23(9):1247	NUM
bptjm-16	381	4	-	-	SYM
bptjm-16	381	5	60	60	NUM
bptjm-16	381	6	.	.	PUNCT
bptjm-16	382	1	doi	doi	NOUN
bptjm-16	382	2	:	:	PUNCT
bptjm-16	382	3	10.1002	10.1002	NUM
bptjm-16	382	4	/	/	SYM
bptjm-16	382	5	neu.480230914	neu.480230914	NOUN
bptjm-16	382	6	.	.	NOUN
bptjm-16	382	7	39	39	NUM
bptjm-16	382	8	.	.	PUNCT
bptjm-16	383	1	muro	muro	PROPN
bptjm-16	383	2	-	-	PUNCT
bptjm-16	383	3	cacho	cacho	NOUN
bptjm-16	383	4	ca	ca	PROPN
bptjm-16	383	5	,	,	PUNCT
bptjm-16	383	6	pontaleo	pontaleo	X
bptjm-16	383	7	g	g	NOUN
bptjm-16	383	8	,	,	PUNCT
bptjm-16	383	9	fauci	fauci	X
bptjm-16	383	10	as	as	ADP
bptjm-16	383	11	.	.	PUNCT
bptjm-16	383	12	analysis	analysis	NOUN
bptjm-16	383	13	of	of	ADP
bptjm-16	383	14	apoptosis	apoptosis	NOUN
bptjm-16	383	15	in	in	ADP
bptjm-16	383	16	lymph	lymph	NOUN
bptjm-16	383	17	nodes	node	NOUN
bptjm-16	383	18	of	of	ADP
bptjm-16	383	19	hivinfected	hivinfecte	VERB
bptjm-16	383	20	persons	person	NOUN
bptjm-16	383	21	.	.	PUNCT
bptjm-16	384	1	j	j	PROPN
bptjm-16	384	2	immunol	immunol	NOUN
bptjm-16	384	3	.	.	PUNCT
bptjm-16	385	1	1995	1995	NUM
bptjm-16	385	2	may	may	PROPN
bptjm-16	385	3	15	15	NUM
bptjm-16	385	4	;	;	PUNCT
bptjm-16	385	5	154(10):5555	154(10):5555	NUM
bptjm-16	385	6	-	-	SYM
bptjm-16	385	7	66	66	NUM
bptjm-16	385	8	.	.	PUNCT
bptjm-16	385	9	40	40	NUM
bptjm-16	385	10	.	.	PUNCT
bptjm-16	386	1	bacchetta	bacchetta	NOUN
bptjm-16	386	2	r	r	NOUN
bptjm-16	386	3	,	,	PUNCT
bptjm-16	386	4	gambineri	gambineri	NOUN
bptjm-16	386	5	e	e	PROPN
bptjm-16	386	6	,	,	PUNCT
bptjm-16	386	7	roncarolo	roncarolo	VERB
bptjm-16	386	8	mg	mg	PROPN
bptjm-16	386	9	.	.	PUNCT
bptjm-16	387	1	role	role	NOUN
bptjm-16	387	2	of	of	ADP
bptjm-16	387	3	regulatory	regulatory	ADJ
bptjm-16	387	4	t	t	NOUN
bptjm-16	387	5	cells	cell	NOUN
bptjm-16	387	6	and	and	CCONJ
bptjm-16	387	7	foxp3	foxp3	NOUN
bptjm-16	387	8	in	in	ADP
bptjm-16	387	9	human	human	ADJ
bptjm-16	387	10	diseases	disease	NOUN
bptjm-16	387	11	.	.	PUNCT
bptjm-16	388	1	j	j	PROPN
bptjm-16	388	2	allergy	allergy	PROPN
bptjm-16	388	3	clin	clin	PROPN
bptjm-16	388	4	immunol	immunol	PROPN
bptjm-16	388	5	.	.	PUNCT
bptjm-16	389	1	2007	2007	NUM
bptjm-16	389	2	aug	aug	NOUN
bptjm-16	389	3	;	;	PUNCT
bptjm-16	389	4	120(2):227	120(2):227	X
bptjm-16	389	5	-	-	SYM
bptjm-16	389	6	35	35	NUM
bptjm-16	389	7	;	;	PUNCT
bptjm-16	389	8	quiz	quiz	NOUN
bptjm-16	389	9	236	236	NUM
bptjm-16	389	10	-	-	SYM
bptjm-16	389	11	7	7	NUM
bptjm-16	389	12	.	.	PUNCT
bptjm-16	389	13	doi	doi	NOUN
bptjm-16	389	14	:	:	PUNCT
bptjm-16	389	15	10.1016	10.1016	NUM
bptjm-16	389	16	/	/	SYM
bptjm-16	389	17	j.jaci.2007.06.023	j.jaci.2007.06.023	PROPN
bptjm-16	389	18	.	.	NOUN
bptjm-16	390	1	41	41	NUM
bptjm-16	390	2	.	.	PUNCT
bptjm-16	391	1	brusko	brusko	PROPN
bptjm-16	391	2	tm	tm	PROPN
bptjm-16	391	3	,	,	PUNCT
bptjm-16	391	4	wasserfall	wasserfall	PROPN
bptjm-16	391	5	ch	ch	PROPN
bptjm-16	391	6	,	,	PUNCT
bptjm-16	391	7	clare	clare	NOUN
bptjm-16	391	8	-	-	PUNCT
bptjm-16	391	9	salzler	salzler	NOUN
bptjm-16	391	10	mj	mj	PROPN
bptjm-16	391	11	,	,	PUNCT
bptjm-16	391	12	schatz	schatz	NOUN
bptjm-16	391	13	da	da	PROPN
bptjm-16	391	14	,	,	PUNCT
bptjm-16	391	15	atkinson	atkinson	PROPN
bptjm-16	391	16	ma	ma	PROPN
bptjm-16	391	17	.	.	PROPN
bptjm-16	392	1	functional	functional	ADJ
bptjm-16	392	2	defects	defect	NOUN
bptjm-16	392	3	and	and	CCONJ
bptjm-16	392	4	the	the	PRON
bptjm-16	392	5	in	in	ADP
bptjm-16	392	6	uence	uence	NOUN
bptjm-16	392	7	of	of	ADP
bptjm-16	392	8	age	age	NOUN
bptjm-16	392	9	on	on	ADP
bptjm-16	392	10	the	the	DET
bptjm-16	392	11	frequency	frequency	NOUN
bptjm-16	392	12	of	of	ADP
bptjm-16	392	13	cd4	cd4	PROPN
bptjm-16	392	14	+	+	PROPN
bptjm-16	392	15	cd25	cd25	PROPN
bptjm-16	392	16	+	+	PROPN
bptjm-16	392	17	t	t	PROPN
bptjm-16	392	18	-	-	PUNCT
bptjm-16	392	19	cells	cell	NOUN
bptjm-16	392	20	in	in	ADP
bptjm-16	392	21	type	type	NOUN
bptjm-16	392	22	1	1	NUM
bptjm-16	392	23	diabetes	diabetes	NOUN
bptjm-16	392	24	.	.	PUNCT
bptjm-16	393	1	diabetes	diabetes	NOUN
bptjm-16	393	2	.	.	PUNCT
bptjm-16	394	1	2005	2005	NUM
bptjm-16	394	2	may	may	AUX
bptjm-16	394	3	;	;	PUNCT
bptjm-16	394	4	54(5):1407	54(5):1407	NUM
bptjm-16	394	5	-	-	SYM
bptjm-16	394	6	14	14	NUM
bptjm-16	394	7	.	.	PUNCT
bptjm-16	395	1	doi	doi	PROPN
bptjm-16	395	2	:	:	PUNCT
bptjm-16	395	3	berkeley	berkeley	PROPN
bptjm-16	395	4	pharma	pharma	PROPN
bptjm-16	395	5	tech	tech	NOUN
bptjm-16	395	6	journal	journal	NOUN
bptjm-16	395	7	of	of	ADP
bptjm-16	395	8	medicine	medicine	NOUN
bptjm-16	395	9	|	|	ADV
bptjm-16	395	10	112	112	NUM
bptjm-16	395	11	10.2337	10.2337	NUM
bptjm-16	395	12	/	/	SYM
bptjm-16	395	13	diabetes.54.5.1407	diabetes.54.5.1407	PROPN
bptjm-16	395	14	.	.	PUNCT
bptjm-16	396	1	42	42	NUM
bptjm-16	396	2	.	.	PUNCT
bptjm-16	397	1	putnam	putnam	PROPN
bptjm-16	397	2	al	al	PROPN
bptjm-16	397	3	,	,	PUNCT
bptjm-16	397	4	vendrame	vendrame	PROPN
bptjm-16	397	5	f	f	NOUN
bptjm-16	397	6	,	,	PUNCT
bptjm-16	397	7	dotta	dotta	PROPN
bptjm-16	397	8	f	f	PROPN
bptjm-16	397	9	,	,	PUNCT
bptjm-16	397	10	gottlieb	gottlieb	PROPN
bptjm-16	397	11	pa	pa	PROPN
bptjm-16	397	12	.	.	PROPN
bptjm-16	397	13	cd4+cd25high	cd4+cd25high	PROPN
bptjm-16	397	14	regulatory	regulatory	PROPN
bptjm-16	397	15	t	t	NOUN
bptjm-16	397	16	cells	cell	NOUN
bptjm-16	397	17	in	in	ADP
bptjm-16	397	18	human	human	ADJ
bptjm-16	397	19	autoimmune	autoimmune	ADJ
bptjm-16	397	20	diabetes	diabetes	NOUN
bptjm-16	397	21	.	.	PUNCT
bptjm-16	398	1	j	j	PROPN
bptjm-16	398	2	autoimmun	autoimmun	PROPN
bptjm-16	398	3	.	.	PUNCT
bptjm-16	399	1	2005	2005	NUM
bptjm-16	399	2	feb	feb	NOUN
bptjm-16	399	3	;	;	PUNCT
bptjm-16	399	4	24(1):55	24(1):55	NOUN
bptjm-16	399	5	-	-	PUNCT
bptjm-16	399	6	62	62	NUM
bptjm-16	399	7	.	.	PUNCT
bptjm-16	400	1	doi	doi	NOUN
bptjm-16	400	2	:	:	PUNCT
bptjm-16	400	3	10.1016	10.1016	NUM
bptjm-16	400	4	/	/	SYM
bptjm-16	400	5	j.jaut.2004.11.004	j.jaut.2004.11.004	PROPN
bptjm-16	400	6	.	.	PUNCT
bptjm-16	401	1	epub	epub	PROPN
bptjm-16	401	2	2005	2005	NUM
bptjm-16	401	3	jan	jan	PROPN
bptjm-16	401	4	12	12	NUM
bptjm-16	401	5	.	.	PUNCT
bptjm-16	401	6	43	43	NUM
bptjm-16	401	7	.	.	PUNCT
bptjm-16	402	1	giordano	giordano	PROPN
bptjm-16	402	2	c	c	PROPN
bptjm-16	402	3	,	,	PUNCT
bptjm-16	402	4	stassi	stassi	ADJ
bptjm-16	402	5	g	g	PROPN
bptjm-16	402	6	,	,	PUNCT
bptjm-16	402	7	de	de	X
bptjm-16	402	8	maria	maria	PROPN
bptjm-16	402	9	r	r	PROPN
bptjm-16	402	10	,	,	PUNCT
bptjm-16	402	11	todaro	todaro	VERB
bptjm-16	402	12	m	m	PRON
bptjm-16	402	13	,	,	PUNCT
bptjm-16	402	14	richiusa	richiusa	VERB
bptjm-16	402	15	p	p	PROPN
bptjm-16	402	16	,	,	PUNCT
bptjm-16	402	17	papo	papo	PROPN
bptjm-16	402	18	g	g	PROPN
bptjm-16	402	19	,	,	PUNCT
bptjm-16	402	20	ruberti	ruberti	NOUN
bptjm-16	402	21	g	g	NOUN
bptjm-16	402	22	,	,	PUNCT
bptjm-16	402	23	bagnasco	bagnasco	PROPN
bptjm-16	402	24	m	m	PROPN
bptjm-16	402	25	,	,	PUNCT
bptjm-16	402	26	testi	testi	PROPN
bptjm-16	402	27	r	r	NOUN
bptjm-16	402	28	,	,	PUNCT
bptjm-16	402	29	galluzzo	galluzzo	NOUN
bptjm-16	402	30	a.	a.	NOUN
bptjm-16	402	31	potential	potential	PROPN
bptjm-16	402	32	involvement	involvement	NOUN
bptjm-16	402	33	of	of	ADP
bptjm-16	402	34	fas	fas	PROPN
bptjm-16	402	35	and	and	CCONJ
bptjm-16	402	36	its	its	PRON
bptjm-16	402	37	ligand	ligand	NOUN
bptjm-16	402	38	in	in	ADP
bptjm-16	402	39	the	the	DET
bptjm-16	402	40	pathogenesis	pathogenesis	NOUN
bptjm-16	402	41	of	of	ADP
bptjm-16	402	42	hashimoto	hashimoto	NOUN
bptjm-16	402	43	's	's	PART
bptjm-16	402	44	thyroiditis	thyroiditis	NOUN
bptjm-16	402	45	.	.	PUNCT
bptjm-16	403	1	science	science	NOUN
bptjm-16	403	2	.	.	PUNCT
bptjm-16	404	1	1997	1997	NUM
bptjm-16	404	2	feb	feb	NOUN
bptjm-16	404	3	14	14	NUM
bptjm-16	404	4	;	;	PUNCT
bptjm-16	404	5	275(5302):960	275(5302):960	NUM
bptjm-16	404	6	-	-	SYM
bptjm-16	404	7	3	3	NUM
bptjm-16	404	8	.	.	PUNCT
bptjm-16	404	9	doi	doi	NOUN
bptjm-16	404	10	:	:	PUNCT
bptjm-16	404	11	10.1126	10.1126	NUM
bptjm-16	404	12	/	/	SYM
bptjm-16	404	13	science.275.5302.960	science.275.5302.960	PROPN
bptjm-16	404	14	.	.	PROPN
bptjm-16	404	15	44	44	NUM
bptjm-16	404	16	.	.	PUNCT
bptjm-16	405	1	hammond	hammond	PROPN
bptjm-16	405	2	lj	lj	PROPN
bptjm-16	405	3	,	,	PUNCT
bptjm-16	405	4	lowdell	lowdell	PROPN
bptjm-16	405	5	mw	mw	PROPN
bptjm-16	405	6	,	,	PUNCT
bptjm-16	405	7	cerrano	cerrano	NOUN
bptjm-16	405	8	pg	pg	PROPN
bptjm-16	405	9	,	,	PUNCT
bptjm-16	405	10	goode	goode	PROPN
bptjm-16	405	11	aw	aw	INTJ
bptjm-16	405	12	,	,	PUNCT
bptjm-16	405	13	bottazzo	bottazzo	VERB
bptjm-16	405	14	gf	gf	PROPN
bptjm-16	405	15	,	,	PUNCT
bptjm-16	405	16	mirakian	mirakian	PROPN
bptjm-16	405	17	r.	r.	PROPN
bptjm-16	405	18	an	an	DET
bptjm-16	405	19	alysisof	alysisof	NOUN
bptjm-16	405	20	apoptosis	apoptosis	NOUN
bptjm-16	405	21	in	in	ADP
bptjm-16	405	22	relation	relation	NOUN
bptjm-16	405	23	to	to	PART
bptjm-16	405	24	tissue	tissue	NOUN
bptjm-16	405	25	destruction	destruction	NOUN
bptjm-16	405	26	associated	associate	VERB
bptjm-16	405	27	with	with	ADP
bptjm-16	405	28	hashimoto	hashimoto	NOUN
bptjm-16	405	29	's	's	PART
bptjm-16	405	30	autoimmune	autoimmune	ADJ
bptjm-16	405	31	thyroiditis	thyroiditis	NOUN
bptjm-16	405	32	.	.	PUNCT
bptjm-16	406	1	j	j	PROPN
bptjm-16	406	2	pathol	pathol	NOUN
bptjm-16	406	3	.	.	PUNCT
bptjm-16	407	1	1997	1997	NUM
bptjm-16	407	2	jun	jun	PROPN
bptjm-16	407	3	;	;	PUNCT
bptjm-16	407	4	182:138	182:138	NUM
bptjm-16	407	5	-	-	SYM
bptjm-16	407	6	144	144	NUM
bptjm-16	407	7	.	.	PUNCT
bptjm-16	408	1	doi:10.1002/(sici)1096	doi:10.1002/(sici)1096	NOUN
bptjm-16	408	2	-	-	PUNCT
bptjm-16	408	3	9896(199706)182:2<13	9896(199706)182:2<13	PROPN
bptjm-16	408	4	8::aid	8::aid	NUM
bptjm-16	408	5	path810>3.0.co;2	path810>3.0.co;2	PROPN
bptjm-16	408	6	-	-	PUNCT
bptjm-16	408	7	f	f	PROPN
bptjm-16	408	8	45	45	NUM
bptjm-16	408	9	.	.	PUNCT
bptjm-16	409	1	emlen	emlen	PROPN
bptjm-16	409	2	w	w	PROPN
bptjm-16	409	3	,	,	PUNCT
bptjm-16	409	4	niebur	niebur	PROPN
bptjm-16	409	5	j	j	PROPN
bptjm-16	409	6	,	,	PUNCT
bptjm-16	409	7	kadera	kadera	PROPN
bptjm-16	409	8	r.	r.	PROPN
bptjm-16	409	9	accelerated	accelerate	VERB
bptjm-16	409	10	in	in	ADP
bptjm-16	409	11	vitro	vitro	X
bptjm-16	409	12	apoptosis	apoptosis	NOUN
bptjm-16	409	13	of	of	ADP
bptjm-16	409	14	lymphocytes	lymphocyte	NOUN
bptjm-16	409	15	from	from	ADP
bptjm-16	409	16	patients	patient	NOUN
bptjm-16	409	17	with	with	ADP
bptjm-16	409	18	systemic	systemic	ADJ
bptjm-16	409	19	lupus	lupus	PROPN
bptjm-16	409	20	erythematosus	erythematosus	PROPN
bptjm-16	409	21	.	.	PUNCT
bptjm-16	410	1	j	j	PROPN
bptjm-16	410	2	immunol	immunol	NOUN
bptjm-16	410	3	.	.	PUNCT
bptjm-16	410	4	1994	1994	NUM
bptjm-16	410	5	;	;	PUNCT
bptjm-16	410	6	152:3685	152:3685	NUM
bptjm-16	410	7	-	-	SYM
bptjm-16	410	8	3692	3692	NUM
bptjm-16	410	9	.	.	PUNCT
bptjm-16	411	1	46	46	NUM
bptjm-16	411	2	.	.	PUNCT
bptjm-16	412	1	von	von	PROPN
bptjm-16	412	2	mühlen	mühlen	PROPN
bptjm-16	412	3	ca	ca	PROPN
bptjm-16	412	4	,	,	PUNCT
bptjm-16	412	5	tan	tan	VERB
bptjm-16	412	6	em	em	PRON
bptjm-16	412	7	.	.	PUNCT
bptjm-16	413	1	autoantibodies	autoantibody	NOUN
bptjm-16	413	2	in	in	ADP
bptjm-16	413	3	the	the	DET
bptjm-16	413	4	diagnosis	diagnosis	NOUN
bptjm-16	413	5	of	of	ADP
bptjm-16	413	6	systemic	systemic	ADJ
bptjm-16	413	7	rheumatic	rheumatic	ADJ
bptjm-16	413	8	diseases	disease	NOUN
bptjm-16	413	9	.	.	PUNCT
bptjm-16	414	1	seminarthritis	seminarthritis	ADJ
bptjm-16	414	2	rheum	rheum	NOUN
bptjm-16	414	3	.	.	PUNCT
bptjm-16	415	1	1995	1995	NUM
bptjm-16	415	2	;	;	PUNCT
bptjm-16	415	3	24:323	24:323	NUM
bptjm-16	415	4	-	-	SYM
bptjm-16	415	5	358	358	NUM
bptjm-16	415	6	.	.	PUNCT
bptjm-16	416	1	doi	doi	NOUN
bptjm-16	416	2	:	:	PUNCT
bptjm-16	416	3	10.1016	10.1016	NUM
bptjm-16	416	4	/	/	SYM
bptjm-16	416	5	s0049	s0049	PROPN
bptjm-16	416	6	-	-	PUNCT
bptjm-16	416	7	0172(95)80004	0172(95)80004	NOUN
bptjm-16	416	8	-	-	PUNCT
bptjm-16	416	9	2	2	NUM
bptjm-16	416	10	.	.	X
bptjm-16	416	11	47	47	NUM
bptjm-16	416	12	.	.	PUNCT
bptjm-16	417	1	cohen	cohen	PROPN
bptjm-16	417	2	pl	pl	PROPN
bptjm-16	417	3	.	.	PROPN
bptjm-16	417	4	apoptotic	apoptotic	ADJ
bptjm-16	417	5	cell	cell	NOUN
bptjm-16	417	6	death	death	NOUN
bptjm-16	417	7	and	and	CCONJ
bptjm-16	417	8	lupus	lupus	NOUN
bptjm-16	417	9	.	.	PUNCT
bptjm-16	418	1	springer	springer	PROPN
bptjm-16	418	2	semin	semin	PROPN
bptjm-16	418	3	immunopathol	immunopathol	PROPN
bptjm-16	418	4	.	.	PUNCT
bptjm-16	419	1	2006	2006	NUM
bptjm-16	419	2	;	;	PUNCT
bptjm-16	419	3	28:145	28:145	NUM
bptjm-16	419	4	-	-	SYM
bptjm-16	419	5	152	152	NUM
bptjm-16	419	6	.	.	PUNCT
bptjm-16	419	7	doi:10.1007	doi:10.1007	VERB
bptjm-16	419	8	/	/	SYM
bptjm-16	419	9	s00281	s00281	NOUN
bptjm-16	419	10	-	-	PUNCT
bptjm-16	419	11	006	006	NUM
bptjm-16	419	12	-	-	PUNCT
bptjm-16	419	13	0038	0038	NUM
bptjm-16	419	14	-	-	PUNCT
bptjm-16	419	15	z	z	NOUN
bptjm-16	419	16	48	48	NUM
bptjm-16	419	17	.	.	PUNCT
bptjm-16	419	18	turbyville	turbyville	PROPN
bptjm-16	419	19	jc	jc	PROPN
bptjm-16	419	20	,	,	PUNCT
bptjm-16	419	21	rao	rao	PROPN
bptjm-16	419	22	vk	vk	PROPN
bptjm-16	419	23	.	.	PUNCT
bptjm-16	420	1	the	the	DET
bptjm-16	420	2	autoimmune	autoimmune	ADJ
bptjm-16	420	3	lymphoproliferative	lymphoproliferative	ADJ
bptjm-16	420	4	syndrome	syndrome	PROPN
bptjm-16	420	5	:	:	PUNCT
bptjm-16	420	6	a	a	DET
bptjm-16	420	7	rare	rare	ADJ
bptjm-16	420	8	disorder	disorder	NOUN
bptjm-16	420	9	providing	provide	VERB
bptjm-16	420	10	clues	clue	NOUN
bptjm-16	420	11	about	about	ADP
bptjm-16	420	12	normal	normal	ADJ
bptjm-16	420	13	tolerance	tolerance	NOUN
bptjm-16	420	14	.	.	PUNCT
bptjm-16	421	1	autoimmun	autoimmun	PROPN
bptjm-16	421	2	rev	rev	PROPN
bptjm-16	421	3	.	.	PROPN
bptjm-16	421	4	2010	2010	NUM
bptjm-16	421	5	;	;	PUNCT
bptjm-16	421	6	9:488	9:488	NUM
bptjm-16	421	7	-	-	SYM
bptjm-16	421	8	493	493	NUM
bptjm-16	421	9	.	.	PUNCT
bptjm-16	422	1	doi:10.1016	doi:10.1016	PROPN
bptjm-16	422	2	/	/	SYM
bptjm-16	422	3	j.autrev.2010.02.007	j.autrev.2010.02.007	PROPN
bptjm-16	422	4	49	49	NUM
bptjm-16	422	5	.	.	PUNCT
bptjm-16	423	1	firestein	firestein	PROPN
bptjm-16	423	2	gs	gs	PROPN
bptjm-16	423	3	,	,	PUNCT
bptjm-16	423	4	yeo	yeo	PROPN
bptjm-16	423	5	m	m	PROPN
bptjm-16	423	6	,	,	PUNCT
bptjm-16	423	7	zvai	zvai	VERB
bptjm-16	423	8	er	er	INTJ
bptjm-16	423	9	nj	nj	INTJ
bptjm-16	423	10	.	.	PUNCT
bptjm-16	424	1	apoptosis	apoptosis	NOUN
bptjm-16	424	2	in	in	ADP
bptjm-16	424	3	rheumatoid	rheumatoid	NOUN
bptjm-16	424	4	arthritis	arthritis	NOUN
bptjm-16	424	5	synovium	synovium	NOUN
bptjm-16	424	6	.	.	PUNCT
bptjm-16	425	1	j	j	PROPN
bptjm-16	425	2	clin	clin	PROPN
bptjm-16	425	3	invest	invest	PROPN
bptjm-16	425	4	.	.	PUNCT
bptjm-16	426	1	1995	1995	NUM
bptjm-16	426	2	;	;	PUNCT
bptjm-16	426	3	96:1631	96:1631	NUM
bptjm-16	426	4	-	-	SYM
bptjm-16	426	5	1638	1638	NUM
bptjm-16	426	6	.	.	PUNCT
bptjm-16	427	1	doi:10.1172	doi:10.1172	PROPN
bptjm-16	427	2	/	/	SYM
bptjm-16	427	3	jci118202	jci118202	PROPN
bptjm-16	427	4	50	50	NUM
bptjm-16	427	5	.	.	PUNCT
bptjm-16	428	1	kerr	kerr	PROPN
bptjm-16	428	2	jf	jf	PROPN
bptjm-16	428	3	,	,	PUNCT
bptjm-16	428	4	wyllie	wyllie	PROPN
bptjm-16	428	5	ah	ah	INTJ
bptjm-16	428	6	,	,	PUNCT
bptjm-16	428	7	currie	currie	PROPN
bptjm-16	428	8	ar	ar	PROPN
bptjm-16	428	9	.	.	PROPN
bptjm-16	428	10	apoptosis	apoptosis	PROPN
bptjm-16	428	11	:	:	PUNCT
bptjm-16	428	12	a	a	DET
bptjm-16	428	13	basic	basic	ADJ
bptjm-16	428	14	biological	biological	ADJ
bptjm-16	428	15	phenomenon	phenomenon	NOUN
bptjm-16	428	16	with	with	ADP
bptjm-16	428	17	wide	wide	ADV
bptjm-16	428	18	-	-	PUNCT
bptjm-16	428	19	ranging	range	VERB
bptjm-16	428	20	implications	implication	NOUN
bptjm-16	428	21	in	in	ADP
bptjm-16	428	22	tissue	tissue	NOUN
bptjm-16	428	23	kinetics	kinetic	NOUN
bptjm-16	428	24	.	.	PUNCT
bptjm-16	429	1	br	br	PROPN
bptjm-16	429	2	j	j	PROPN
bptjm-16	429	3	cancer	cancer	NOUN
bptjm-16	429	4	.	.	PUNCT
bptjm-16	430	1	1972	1972	NUM
bptjm-16	430	2	;	;	PUNCT
bptjm-16	430	3	26:239–57	26:239–57	PROPN
bptjm-16	430	4	51	51	NUM
bptjm-16	430	5	.	.	PUNCT
bptjm-16	431	1	majno	majno	PROPN
bptjm-16	431	2	g	g	PROPN
bptjm-16	431	3	,	,	PUNCT
bptjm-16	431	4	joris	joris	PROPN
bptjm-16	431	5	i.	i.	PROPN
bptjm-16	431	6	apoptosis	apoptosis	PROPN
bptjm-16	431	7	,	,	PUNCT
bptjm-16	431	8	oncosis	oncosis	NOUN
bptjm-16	431	9	,	,	PUNCT
bptjm-16	431	10	and	and	CCONJ
bptjm-16	431	11	necrosis	necrosis	NOUN
bptjm-16	431	12	.	.	PUNCT
bptjm-16	432	1	an	an	DET
bptjm-16	432	2	overview	overview	NOUN
bptjm-16	432	3	of	of	ADP
bptjm-16	432	4	cell	cell	NOUN
bptjm-16	432	5	death	death	NOUN
bptjm-16	432	6	.	.	PUNCT
bptjm-16	433	1	am	be	AUX
bptjm-16	433	2	j	j	PROPN
bptjm-16	433	3	pathol	pathol	NOUN
bptjm-16	433	4	.	.	PUNCT
bptjm-16	434	1	1995	1995	NUM
bptjm-16	434	2	;	;	PUNCT
bptjm-16	434	3	146:3–15	146:3–15	NUM
bptjm-16	434	4	52	52	NUM
bptjm-16	434	5	.	.	PUNCT
bptjm-16	435	1	trump	trump	NOUN
bptjm-16	435	2	bf	bf	PROPN
bptjm-16	435	3	,	,	PUNCT
bptjm-16	435	4	berezesky	berezesky	ADJ
bptjm-16	435	5	ik	ik	PROPN
bptjm-16	435	6	,	,	PUNCT
bptjm-16	435	7	chang	chang	PROPN
bptjm-16	435	8	sh	sh	PROPN
bptjm-16	435	9	,	,	PUNCT
bptjm-16	435	10	phelps	phelps	PROPN
bptjm-16	435	11	pc	pc	PROPN
bptjm-16	435	12	.	.	PUNCT
bptjm-16	436	1	the	the	DET
bptjm-16	436	2	pathways	pathway	NOUN
bptjm-16	436	3	of	of	ADP
bptjm-16	436	4	cell	cell	NOUN
bptjm-16	436	5	death	death	NOUN
bptjm-16	436	6	:	:	PUNCT
bptjm-16	436	7	oncosis	oncosis	NOUN
bptjm-16	436	8	,	,	PUNCT
bptjm-16	436	9	apoptosis	apoptosis	NOUN
bptjm-16	436	10	,	,	PUNCT
bptjm-16	436	11	and	and	CCONJ
bptjm-16	436	12	necrosis	necrosis	NOUN
bptjm-16	436	13	.	.	PUNCT
bptjm-16	437	1	toxicol	toxicol	PROPN
bptjm-16	437	2	pathol	pathol	NOUN
bptjm-16	437	3	.	.	PUNCT
bptjm-16	437	4	1997	1997	NUM
bptjm-16	437	5	;	;	PUNCT
bptjm-16	437	6	25:82–8	25:82–8	PROPN
bptjm-16	437	7	53	53	NUM
bptjm-16	437	8	.	.	PUNCT
bptjm-16	438	1	zeiss	zeiss	PROPN
bptjm-16	438	2	cj	cj	PROPN
bptjm-16	438	3	.	.	PUNCT
bptjm-16	439	1	the	the	DET
bptjm-16	439	2	apoptosis	apoptosis	NOUN
bptjm-16	439	3	-	-	PUNCT
bptjm-16	439	4	necrosis	necrosis	NOUN
bptjm-16	439	5	continuum	continuum	NOUN
bptjm-16	439	6	:	:	PUNCT
bptjm-16	439	7	insights	insight	NOUN
bptjm-16	439	8	from	from	ADP
bptjm-16	439	9	genetically	genetically	ADV
bptjm-16	439	10	altered	alter	VERB
bptjm-16	439	11	mice.vet	mice.vet	NOUN
bptjm-16	439	12	pathol	pathol	NOUN
bptjm-16	439	13	.	.	PUNCT
bptjm-16	440	1	2003	2003	NUM
bptjm-16	440	2	;	;	PUNCT
bptjm-16	440	3	40:481–95	40:481–95	PROPN
bptjm-16	440	4	54	54	NUM
bptjm-16	440	5	.	.	PUNCT
bptjm-16	441	1	denecker	denecker	PROPN
bptjm-16	441	2	g	g	NOUN
bptjm-16	441	3	,	,	PUNCT
bptjm-16	441	4	vercammen	vercammen	PROPN
bptjm-16	441	5	d	d	VERB
bptjm-16	441	6	,	,	PUNCT
bptjm-16	441	7	declercq	declercq	NOUN
bptjm-16	441	8	w	w	PROPN
bptjm-16	441	9	,	,	PUNCT
bptjm-16	441	10	vandenabeele	vandenabeele	NOUN
bptjm-16	441	11	p.	p.	NOUN
bptjm-16	441	12	apoptotic	apoptotic	ADJ
bptjm-16	441	13	and	and	CCONJ
bptjm-16	441	14	necrotic	necrotic	ADJ
bptjm-16	441	15	cell	cell	NOUN
bptjm-16	441	16	death	death	NOUN
bptjm-16	441	17	induced	induce	VERB
bptjm-16	441	18	by	by	ADP
bptjm-16	441	19	death	death	NOUN
bptjm-16	441	20	domain	domain	NOUN
bptjm-16	441	21	receptors	receptor	NOUN
bptjm-16	441	22	.	.	PUNCT
bptjm-16	442	1	cell	cell	NOUN
bptjm-16	442	2	mol	mol	ADP
bptjm-16	442	3	life	life	PROPN
bptjm-16	442	4	sci	sci	PROPN
bptjm-16	442	5	.	.	PROPN
bptjm-16	442	6	2001	2001	NUM
bptjm-16	442	7	;	;	PUNCT
bptjm-16	442	8	58:356–70	58:356–70	PROPN
bptjm-16	442	9	55	55	NUM
bptjm-16	442	10	.	.	PUNCT
bptjm-16	443	1	leist	leist	PROPN
bptjm-16	443	2	m	m	PROPN
bptjm-16	443	3	,	,	PUNCT
bptjm-16	443	4	single	single	ADJ
bptjm-16	443	5	b	b	PROPN
bptjm-16	443	6	,	,	PUNCT
bptjm-16	443	7	castoldiaf	castoldiaf	NOUN
bptjm-16	443	8	,	,	PUNCT
bptjm-16	443	9	kuhnle	kuhnle	PROPN
bptjm-16	443	10	s	s	PROPN
bptjm-16	443	11	,	,	PUNCT
bptjm-16	443	12	nicotera	nicotera	NOUN
bptjm-16	443	13	p.	p.	NOUN
bptjm-16	443	14	intracellular	intracellular	ADJ
bptjm-16	443	15	adenosine	adenosine	NOUN
bptjm-16	443	16	triphosphate	triphosphate	NOUN
bptjm-16	443	17	(	(	PUNCT
bptjm-16	443	18	atp	atp	NOUN
bptjm-16	443	19	)	)	PUNCT
bptjm-16	443	20	concentration	concentration	NOUN
bptjm-16	443	21	:	:	PUNCT
bptjm-16	443	22	a	a	DET
bptjm-16	443	23	switch	switch	NOUN
bptjm-16	443	24	in	in	ADP
bptjm-16	443	25	the	the	DET
bptjm-16	443	26	decision	decision	NOUN
bptjm-16	443	27	between	between	ADP
bptjm-16	443	28	apoptosis	apoptosis	NOUN
bptjm-16	443	29	and	and	CCONJ
bptjm-16	443	30	necrosis	necrosis	NOUN
bptjm-16	443	31	.	.	PUNCT
bptjm-16	444	1	j	j	PROPN
bptjm-16	444	2	exp	exp	NOUN
bptjm-16	444	3	med	med	PROPN
bptjm-16	444	4	.	.	PUNCT
bptjm-16	444	5	1997	1997	NUM
bptjm-16	444	6	;	;	PUNCT
bptjm-16	444	7	185:1481–6	185:1481–6	NUM
bptjm-16	444	8	56	56	NUM
bptjm-16	444	9	.	.	PUNCT
bptjm-16	445	1	fiers	fiers	PROPN
bptjm-16	445	2	w	w	PROPN
bptjm-16	445	3	,	,	PUNCT
bptjm-16	445	4	beyaert	beyaert	ADJ
bptjm-16	445	5	r	r	NOUN
bptjm-16	445	6	,	,	PUNCT
bptjm-16	445	7	declercq	declercq	NOUN
bptjm-16	445	8	w	w	NOUN
bptjm-16	445	9	,	,	PUNCT
bptjm-16	445	10	vandenabeele	vandenabeele	NOUN
bptjm-16	445	11	p.	p.	NOUN
bptjm-16	445	12	more	more	ADJ
bptjm-16	445	13	than	than	ADP
bptjm-16	445	14	one	one	NUM
bptjm-16	445	15	way	way	NOUN
bptjm-16	445	16	to	to	PART
bptjm-16	445	17	die	die	VERB
bptjm-16	445	18	:	:	PUNCT
bptjm-16	445	19	apoptosis	apoptosis	NOUN
bptjm-16	445	20	,	,	PUNCT
bptjm-16	445	21	necrosis	necrosis	NOUN
bptjm-16	445	22	and	and	CCONJ
bptjm-16	445	23	reactive	reactive	ADJ
bptjm-16	445	24	oxygen	oxygen	NOUN
bptjm-16	445	25	damage.oncogene	damage.oncogene	NOUN
bptjm-16	445	26	.	.	PROPN
bptjm-16	445	27	1999	1999	NUM
bptjm-16	445	28	;	;	PUNCT
bptjm-16	445	29	18:7719–30	18:7719–30	NUM
bptjm-16	445	30	57	57	NUM
bptjm-16	445	31	.	.	PUNCT
bptjm-16	446	1	kurosaka	kurosaka	PROPN
bptjm-16	447	1	k	k	X
bptjm-16	447	2	,	,	PUNCT
bptjm-16	447	3	takahashi	takahashi	PROPN
bptjm-16	447	4	m	m	PROPN
bptjm-16	447	5	,	,	PUNCT
bptjm-16	447	6	watanabe	watanabe	PROPN
bptjm-16	447	7	n	n	PROPN
bptjm-16	447	8	,	,	PUNCT
bptjm-16	447	9	berkeley	berkeley	PROPN
bptjm-16	447	10	pharma	pharma	PROPN
bptjm-16	447	11	tech	tech	NOUN
bptjm-16	447	12	journal	journal	NOUN
bptjm-16	447	13	of	of	ADP
bptjm-16	447	14	medicine	medicine	NOUN
bptjm-16	447	15	|	|	ADV
bptjm-16	447	16	113	113	NUM
bptjm-16	447	17	kobayashi	kobayashi	PROPN
bptjm-16	447	18	y.	y.	PROPN
bptjm-16	447	19	silent	silent	PROPN
bptjm-16	447	20	cleanup	cleanup	NOUN
bptjm-16	447	21	of	of	ADP
bptjm-16	447	22	very	very	ADV
bptjm-16	447	23	early	early	ADJ
bptjm-16	447	24	apoptotic	apoptotic	ADJ
bptjm-16	447	25	cells	cell	NOUN
bptjm-16	447	26	by	by	ADP
bptjm-16	447	27	macrophages	macrophage	NOUN
bptjm-16	447	28	.	.	PUNCT
bptjm-16	448	1	j	j	PROPN
bptjm-16	448	2	immunol	immunol	NOUN
bptjm-16	448	3	.	.	PUNCT
bptjm-16	448	4	2003	2003	NUM
bptjm-16	448	5	;	;	PUNCT
bptjm-16	448	6	171:4672–9	171:4672–9	NUM
bptjm-16	448	7	58	58	NUM
bptjm-16	448	8	.	.	PUNCT
bptjm-16	449	1	savill	savill	PROPN
bptjm-16	449	2	j	j	NOUN
bptjm-16	449	3	,	,	PUNCT
bptjm-16	449	4	fadok	fadok	PROPN
bptjm-16	449	5	v.	v.	ADP
bptjm-16	449	6	corpse	corpse	NOUN
bptjm-16	449	7	clearance	clearance	NOUN
bptjm-16	449	8	de	de	X
bptjm-16	449	9	nes	nes	PROPN
bptjm-16	449	10	the	the	DET
bptjm-16	449	11	meaning	meaning	NOUN
bptjm-16	449	12	of	of	ADP
bptjm-16	449	13	cell	cell	NOUN
bptjm-16	449	14	death.nature	death.nature	NOUN
bptjm-16	449	15	.	.	PUNCT
bptjm-16	450	1	2000	2000	NUM
bptjm-16	450	2	;	;	PUNCT
bptjm-16	451	1	407:784–8	407:784–8	X
bptjm-16	451	2	.	.	PUNCT
bptjm-16	452	1	59	59	NUM
bptjm-16	452	2	.	.	PUNCT
bptjm-16	453	1	feng	feng	PROPN
bptjm-16	453	2	s	s	PROPN
bptjm-16	453	3	,	,	PUNCT
bptjm-16	453	4	yang	yang	PROPN
bptjm-16	453	5	y	y	PROPN
bptjm-16	453	6	,	,	PUNCT
bptjm-16	453	7	mei	mei	PROPN
bptjm-16	453	8	y	y	PROPN
bptjm-16	453	9	,	,	PUNCT
bptjm-16	453	10	ma	ma	PROPN
bptjm-16	453	11	l	l	PROPN
bptjm-16	453	12	,	,	PUNCT
bptjm-16	453	13	zhu	zhu	PROPN
bptjm-16	453	14	de	de	X
bptjm-16	453	15	,	,	PUNCT
bptjm-16	453	16	hoti	hoti	PROPN
bptjm-16	453	17	n	n	CCONJ
bptjm-16	453	18	,	,	PUNCT
bptjm-16	453	19	castanares	castanare	VERB
bptjm-16	453	20	m	m	PROPN
bptjm-16	453	21	,	,	PUNCT
bptjm-16	453	22	wu	wu	PROPN
bptjm-16	453	23	m.	m.	NOUN
bptjm-16	453	24	cleavage	cleavage	NOUN
bptjm-16	453	25	of	of	ADP
bptjm-16	453	26	rip3	rip3	PROPN
bptjm-16	453	27	inactivates	inactivate	VERB
bptjm-16	453	28	its	its	PRON
bptjm-16	453	29	caspase	caspase	NOUN
bptjm-16	453	30	-	-	PUNCT
bptjm-16	453	31	independent	independent	ADJ
bptjm-16	453	32	apoptosis	apoptosis	NOUN
bptjm-16	453	33	pathway	pathway	NOUN
bptjm-16	453	34	by	by	ADP
bptjm-16	453	35	removal	removal	NOUN
bptjm-16	453	36	of	of	ADP
bptjm-16	453	37	kinase	kinase	PROPN
bptjm-16	453	38	domain	domain	NOUN
bptjm-16	453	39	.	.	PUNCT
bptjm-16	454	1	cell	cell	NOUN
bptjm-16	454	2	signal	signal	NOUN
bptjm-16	454	3	.	.	PUNCT
bptjm-16	455	1	2007	2007	NUM
bptjm-16	455	2	oct	oct	NOUN
bptjm-16	455	3	;	;	PUNCT
bptjm-16	455	4	19(10):2056	19(10):2056	NUM
bptjm-16	455	5	-	-	SYM
bptjm-16	455	6	67	67	NUM
bptjm-16	455	7	.	.	PUNCT
bptjm-16	456	1	doi	doi	NOUN
bptjm-16	456	2	:	:	PUNCT
bptjm-16	456	3	10.1016	10.1016	NUM
bptjm-16	456	4	/	/	SYM
bptjm-16	456	5	j.cellsig.2007.05.016	j.cellsig.2007.05.016	PROPN
bptjm-16	456	6	.	.	PUNCT
bptjm-16	457	1	60	60	NUM
bptjm-16	457	2	.	.	PUNCT
bptjm-16	458	1	lin	lin	PROPN
bptjm-16	458	2	y	y	PROPN
bptjm-16	458	3	,	,	PUNCT
bptjm-16	458	4	devin	devin	PROPN
bptjm-16	458	5	a	a	PRON
bptjm-16	458	6	,	,	PUNCT
bptjm-16	458	7	rodriguez	rodriguez	PROPN
bptjm-16	458	8	y	y	PROPN
bptjm-16	458	9	,	,	PUNCT
bptjm-16	458	10	liu	liu	PROPN
bptjm-16	458	11	zg	zg	PROPN
bptjm-16	458	12	.	.	PUNCT
bptjm-16	458	13	cleavage	cleavage	NOUN
bptjm-16	458	14	of	of	ADP
bptjm-16	458	15	the	the	DET
bptjm-16	458	16	death	death	NOUN
bptjm-16	458	17	domain	domain	NOUN
bptjm-16	458	18	kinase	kinase	PROPN
bptjm-16	458	19	rip	rip	VERB
bptjm-16	458	20	by	by	ADP
bptjm-16	458	21	caspase-8	caspase-8	PROPN
bptjm-16	458	22	prompts	prompt	VERB
bptjm-16	458	23	tnf	tnf	PROPN
bptjm-16	458	24	-	-	PUNCT
bptjm-16	458	25	induced	induce	VERB
bptjm-16	458	26	apoptosis	apoptosis	NOUN
bptjm-16	458	27	.	.	PUNCT
bptjm-16	459	1	genes	gene	NOUN
bptjm-16	459	2	dev	dev	PROPN
bptjm-16	459	3	.	.	PROPN
bptjm-16	459	4	1999	1999	NUM
bptjm-16	459	5	oct	oct	PROPN
bptjm-16	459	6	1	1	NUM
bptjm-16	459	7	;	;	PUNCT
bptjm-16	459	8	13(19):2514	13(19):2514	NUM
bptjm-16	459	9	-	-	SYM
bptjm-16	459	10	26	26	NUM
bptjm-16	459	11	.	.	PUNCT
bptjm-16	460	1	doi	doi	NOUN
bptjm-16	460	2	:	:	PUNCT
bptjm-16	460	3	10.1101	10.1101	NUM
bptjm-16	460	4	/	/	SYM
bptjm-16	460	5	gad.13.19.2514	gad.13.19.2514	NOUN
bptjm-16	460	6	61	61	NUM
bptjm-16	460	7	.	.	PUNCT
bptjm-16	461	1	mandal	mandal	PROPN
bptjm-16	461	2	p	p	PROPN
bptjm-16	461	3	,	,	PUNCT
bptjm-16	461	4	berger	berger	PROPN
bptjm-16	461	5	sb	sb	PROPN
bptjm-16	461	6	,	,	PUNCT
bptjm-16	461	7	pillay	pillay	PROPN
bptjm-16	461	8	s	s	PROPN
bptjm-16	461	9	,	,	PUNCT
bptjm-16	461	10	moriwaki	moriwaki	PROPN
bptjm-16	461	11	k	k	PROPN
bptjm-16	461	12	,	,	PUNCT
bptjm-16	461	13	huang	huang	PROPN
bptjm-16	461	14	c	c	PROPN
bptjm-16	461	15	,	,	PUNCT
bptjm-16	461	16	guo	guo	PROPN
bptjm-16	461	17	h	h	PROPN
bptjm-16	461	18	,	,	PUNCT
bptjm-16	461	19	lich	lich	PROPN
bptjm-16	461	20	jd	jd	PROPN
bptjm-16	461	21	,	,	PUNCT
bptjm-16	461	22	finger	finger	PROPN
bptjm-16	461	23	j	j	PROPN
bptjm-16	461	24	,	,	PUNCT
bptjm-16	461	25	kasparcova	kasparcova	X
bptjm-16	461	26	v	v	ADP
bptjm-16	461	27	,	,	PUNCT
bptjm-16	461	28	votta	votta	PROPN
bptjm-16	461	29	b	b	PROPN
bptjm-16	461	30	,	,	PUNCT
bptjm-16	461	31	ouellette	ouellette	PROPN
bptjm-16	461	32	m	m	PROPN
bptjm-16	461	33	,	,	PUNCT
bptjm-16	461	34	king	king	PROPN
bptjm-16	461	35	bw	bw	PROPN
bptjm-16	461	36	,	,	PUNCT
bptjm-16	461	37	wisnoski	wisnoski	ADJ
bptjm-16	461	38	d	d	NOUN
bptjm-16	461	39	,	,	PUNCT
bptjm-16	461	40	lakdawala	lakdawala	PROPN
bptjm-16	461	41	as	as	ADP
bptjm-16	461	42	,	,	PUNCT
bptjm-16	461	43	demartino	demartino	PROPN
bptjm-16	461	44	mp	mp	PROPN
bptjm-16	461	45	,	,	PUNCT
bptjm-16	461	46	casillas	casillas	PROPN
bptjm-16	461	47	ln	ln	PROPN
bptjm-16	461	48	,	,	PUNCT
bptjm-16	461	49	haile	haile	PROPN
bptjm-16	461	50	pa	pa	PROPN
bptjm-16	461	51	,	,	PUNCT
bptjm-16	461	52	sehon	sehon	PROPN
bptjm-16	461	53	ca	ca	PROPN
bptjm-16	461	54	,	,	PUNCT
bptjm-16	461	55	marquis	marquis	PROPN
bptjm-16	461	56	rw	rw	PROPN
bptjm-16	461	57	,	,	PUNCT
bptjm-16	461	58	upton	upton	PROPN
bptjm-16	461	59	j	j	PROPN
bptjm-16	461	60	,	,	PUNCT
bptjm-16	461	61	daley	daley	PROPN
bptjm-16	461	62	-	-	PUNCT
bptjm-16	461	63	bauer	bauer	PROPN
bptjm-16	461	64	lp	lp	PROPN
bptjm-16	461	65	,	,	PUNCT
bptjm-16	461	66	roback	roback	PROPN
bptjm-16	461	67	l	l	NOUN
bptjm-16	461	68	,	,	PUNCT
bptjm-16	461	69	ramia	ramia	NOUN
bptjm-16	461	70	n	n	CCONJ
bptjm-16	461	71	,	,	PUNCT
bptjm-16	461	72	dovey	dovey	ADJ
bptjm-16	461	73	cm	cm	NOUN
bptjm-16	461	74	,	,	PUNCT
bptjm-16	461	75	carette	carette	PROPN
bptjm-16	461	76	je	je	PROPN
bptjm-16	461	77	,	,	PUNCT
bptjm-16	461	78	chan	chan	PROPN
bptjm-16	461	79	fk	fk	PROPN
bptjm-16	461	80	,	,	PUNCT
bptjm-16	461	81	bertin	bertin	PROPN
bptjm-16	461	82	j	j	PROPN
bptjm-16	461	83	,	,	PUNCT
bptjm-16	461	84	gough	gough	PROPN
bptjm-16	461	85	pj	pj	PROPN
bptjm-16	461	86	,	,	PUNCT
bptjm-16	461	87	mocarski	mocarski	NOUN
bptjm-16	461	88	es	es	NOUN
bptjm-16	461	89	,	,	PUNCT
bptjm-16	461	90	kaiser	kaiser	PROPN
bptjm-16	461	91	wj	wj	PROPN
bptjm-16	461	92	.	.	PUNCT
bptjm-16	461	93	rip3	rip3	PROPN
bptjm-16	461	94	induces	induce	VERB
bptjm-16	461	95	apoptosis	apoptosis	NOUN
bptjm-16	461	96	independent	independent	ADJ
bptjm-16	461	97	of	of	ADP
bptjm-16	461	98	pronecrotic	pronecrotic	ADJ
bptjm-16	461	99	kinase	kinase	PROPN
bptjm-16	461	100	activity.mol	activity.mol	PROPN
bptjm-16	461	101	cell	cell	NOUN
bptjm-16	461	102	.	.	PUNCT
bptjm-16	462	1	2014	2014	NUM
bptjm-16	462	2	nov	nov	NOUN
bptjm-16	462	3	20	20	NUM
bptjm-16	462	4	;	;	PUNCT
bptjm-16	462	5	56(4):481	56(4):481	NUM
bptjm-16	462	6	-	-	PUNCT
bptjm-16	462	7	95	95	NUM
bptjm-16	462	8	.	.	PUNCT
bptjm-16	463	1	doi	doi	NOUN
bptjm-16	463	2	:	:	PUNCT
bptjm-16	463	3	10.1016	10.1016	NUM
bptjm-16	463	4	/	/	SYM
bptjm-16	463	5	j.molcel.2014.10.021	j.molcel.2014.10.021	PROPN
bptjm-16	463	6	.	.	PROPN
bptjm-16	464	1	62	62	NUM
bptjm-16	464	2	.	.	PUNCT
bptjm-16	465	1	moriwaki	moriwaki	PROPN
bptjm-16	465	2	k	k	PROPN
bptjm-16	465	3	,	,	PUNCT
bptjm-16	465	4	chan	chan	PROPN
bptjm-16	465	5	fk	fk	INTJ
bptjm-16	465	6	.	.	PUNCT
bptjm-16	466	1	rip3	rip3	PROPN
bptjm-16	466	2	:	:	PUNCT
bptjm-16	466	3	a	a	DET
bptjm-16	466	4	molecular	molecular	ADJ
bptjm-16	466	5	switch	switch	NOUN
bptjm-16	466	6	for	for	ADP
bptjm-16	466	7	necrosis	necrosis	NOUN
bptjm-16	466	8	and	and	CCONJ
bptjm-16	466	9	in	in	ADP
bptjm-16	466	10	ammation.genes	ammation.genes	PROPN
bptjm-16	466	11	dev	dev	PROPN
bptjm-16	466	12	.	.	PUNCT
bptjm-16	467	1	2013aug	2013aug	NUM
bptjm-16	467	2	1	1	NUM
bptjm-16	467	3	;	;	PUNCT
bptjm-16	468	1	27(15):1640	27(15):1640	NUM
bptjm-16	468	2	-	-	SYM
bptjm-16	468	3	9	9	NUM
bptjm-16	468	4	.	.	PUNCT
bptjm-16	468	5	doi	doi	NOUN
bptjm-16	468	6	:	:	PUNCT
bptjm-16	468	7	10.1101	10.1101	NUM
bptjm-16	468	8	/	/	SYM
bptjm-16	468	9	gad.223321.113	gad.223321.113	NOUN
bptjm-16	468	10	.	.	PUNCT
bptjm-16	469	1	63	63	NUM
bptjm-16	469	2	.	.	PUNCT
bptjm-16	470	1	khoury	khoury	PROPN
bptjm-16	470	2	m.	m.	PROPN
bptjm-16	470	3	,	,	PUNCT
bptjm-16	470	4	gupta	gupta	PROPN
bptjm-16	470	5	k.	k.	PROPN
bptjm-16	470	6	,	,	PUNCT
bptjm-16	470	7	franco	franco	PROPN
bptjm-16	470	8	s.	s.	PROPN
bptjm-16	470	9	,	,	PUNCT
bptjm-16	470	10	liu	liu	PROPN
bptjm-16	470	11	b.	b.	PROPN
bptjm-16	470	12	necroptosis	necroptosis	PROPN
bptjm-16	470	13	in	in	ADP
bptjm-16	470	14	the	the	DET
bptjm-16	470	15	pathophysiology	pathophysiology	NOUN
bptjm-16	470	16	of	of	ADP
bptjm-16	470	17	disease	disease	NOUN
bptjm-16	470	18	.	.	PUNCT
bptjm-16	471	1	the	the	DET
bptjm-16	471	2	american	american	PROPN
bptjm-16	471	3	journal	journal	PROPN
bptjm-16	471	4	of	of	ADP
bptjm-16	471	5	pathology	pathology	PROPN
bptjm-16	471	6	.	.	PUNCT
bptjm-16	471	7	2019	2019	NUM
bptjm-16	471	8	;	;	PUNCT
bptjm-16	471	9	190(2):272	190(2):272	NUM
bptjm-16	471	10	-	-	PUNCT
bptjm-16	471	11	285	285	NUM
bptjm-16	471	12	.	.	PUNCT
bptjm-16	472	1	doi	doi	NOUN
bptjm-16	472	2	:	:	PUNCT
bptjm-16	472	3	https://doi.org/10.1016/	https://doi.org/10.1016/	PROPN
bptjm-16	472	4	j.ajpath.2019.10.012	j.ajpath.2019.10.012	PRON
bptjm-16	472	5	64	64	NUM
bptjm-16	472	6	.	.	PUNCT
bptjm-16	473	1	christo	christo	PROPN
bptjm-16	473	2	erson	erson	PROPN
bptjm-16	473	3	de	de	PROPN
bptjm-16	473	4	,	,	PUNCT
bptjm-16	473	5	yuan	yuan	PROPN
bptjm-16	473	6	j.	j.	PROPN
bptjm-16	473	7	necroptosis	necroptosis	PROPN
bptjm-16	473	8	as	as	ADP
bptjm-16	473	9	an	an	DET
bptjm-16	473	10	alternative	alternative	ADJ
bptjm-16	473	11	form	form	NOUN
bptjm-16	473	12	of	of	ADP
bptjm-16	473	13	programmed	program	VERB
bptjm-16	473	14	cell	cell	NOUN
bptjm-16	473	15	death	death	NOUN
bptjm-16	473	16	.	.	PUNCT
bptjm-16	474	1	curr	curr	PROPN
bptjm-16	474	2	opin	opin	NOUN
bptjm-16	474	3	cell	cell	NOUN
bptjm-16	474	4	biol	biol	NOUN
bptjm-16	474	5	.	.	PUNCT
bptjm-16	475	1	2010	2010	NUM
bptjm-16	475	2	apr	apr	NOUN
bptjm-16	475	3	;	;	PUNCT
bptjm-16	475	4	22(2):263	22(2):263	NUM
bptjm-16	475	5	-	-	SYM
bptjm-16	475	6	8	8	NUM
bptjm-16	475	7	.	.	PUNCT
bptjm-16	476	1	doi	doi	NOUN
bptjm-16	476	2	:	:	PUNCT
bptjm-16	476	3	10.1016	10.1016	NUM
bptjm-16	476	4	/	/	SYM
bptjm-16	476	5	j.ceb.2009.12.003	j.ceb.2009.12.003	NOUN
bptjm-16	476	6	.	.	PROPN
bptjm-16	476	7	65	65	NUM
bptjm-16	476	8	.	.	PUNCT
bptjm-16	477	1	sun	sun	PROPN
bptjm-16	477	2	l	l	PROPN
bptjm-16	477	3	,	,	PUNCT
bptjm-16	477	4	wang	wang	PROPN
bptjm-16	477	5	h	h	PROPN
bptjm-16	477	6	,	,	PUNCT
bptjm-16	477	7	wang	wang	PROPN
bptjm-16	477	8	z	z	PROPN
bptjm-16	477	9	,	,	PUNCT
bptjm-16	477	10	he	he	PRON
bptjm-16	477	11	s	s	PROPN
bptjm-16	477	12	,	,	PUNCT
bptjm-16	477	13	chen	chen	PROPN
bptjm-16	477	14	s	s	PROPN
bptjm-16	477	15	,	,	PUNCT
bptjm-16	477	16	liao	liao	PROPN
bptjm-16	477	17	d	d	PROPN
bptjm-16	477	18	,	,	PUNCT
bptjm-16	477	19	wang	wang	PROPN
bptjm-16	477	20	l	l	PROPN
bptjm-16	477	21	,	,	PUNCT
bptjm-16	477	22	yan	yan	PROPN
bptjm-16	477	23	j	j	PROPN
bptjm-16	477	24	,	,	PUNCT
bptjm-16	477	25	liu	liu	PROPN
bptjm-16	477	26	w	w	PROPN
bptjm-16	477	27	,	,	PUNCT
bptjm-16	477	28	lei	lei	X
bptjm-16	477	29	x	x	NOUN
bptjm-16	477	30	,	,	PUNCT
bptjm-16	477	31	wang	wang	PROPN
bptjm-16	477	32	x.	x.	PROPN
bptjm-16	477	33	mixed	mixed	PROPN
bptjm-16	477	34	lineage	lineage	PROPN
bptjm-16	477	35	kinase	kinase	NOUN
bptjm-16	477	36	domain	domain	NOUN
bptjm-16	477	37	-	-	PUNCT
bptjm-16	477	38	like	like	ADJ
bptjm-16	477	39	protein	protein	NOUN
bptjm-16	477	40	mediates	mediate	NOUN
bptjm-16	477	41	necrosis	necrosis	NOUN
bptjm-16	477	42	signaling	signal	VERB
bptjm-16	477	43	downstream	downstream	NOUN
bptjm-16	477	44	of	of	ADP
bptjm-16	477	45	rip3	rip3	PROPN
bptjm-16	477	46	kinase	kinase	PROPN
bptjm-16	477	47	.	.	PUNCT
bptjm-16	478	1	cell	cell	NOUN
bptjm-16	478	2	.	.	PUNCT
bptjm-16	479	1	2012	2012	NUM
bptjm-16	479	2	jan	jan	PROPN
bptjm-16	479	3	20	20	NUM
bptjm-16	479	4	;	;	PUNCT
bptjm-16	479	5	148(1	148(1	NUM
bptjm-16	479	6	-	-	SYM
bptjm-16	479	7	2):213	2):213	NUM
bptjm-16	479	8	-	-	PUNCT
bptjm-16	479	9	27	27	NUM
bptjm-16	479	10	.	.	PUNCT
bptjm-16	480	1	doi	doi	NOUN
bptjm-16	480	2	:	:	PUNCT
bptjm-16	480	3	10.1016	10.1016	NUM
bptjm-16	480	4	/	/	SYM
bptjm-16	480	5	j.cell.2011.11.031	j.cell.2011.11.031	PROPN
bptjm-16	480	6	.	.	PROPN
bptjm-16	481	1	66	66	NUM
bptjm-16	481	2	.	.	PUNCT
bptjm-16	482	1	wang	wang	PROPN
bptjm-16	482	2	h	h	PROPN
bptjm-16	482	3	,	,	PUNCT
bptjm-16	482	4	sun	sun	PROPN
bptjm-16	482	5	l	l	PROPN
bptjm-16	482	6	,	,	PUNCT
bptjm-16	482	7	su	su	PROPN
bptjm-16	482	8	l	l	PROPN
bptjm-16	482	9	,	,	PUNCT
bptjm-16	482	10	rizo	rizo	PROPN
bptjm-16	482	11	j	j	PROPN
bptjm-16	482	12	,	,	PUNCT
bptjm-16	482	13	liu	liu	PROPN
bptjm-16	482	14	l	l	PROPN
bptjm-16	482	15	,	,	PUNCT
bptjm-16	482	16	wang	wang	PROPN
bptjm-16	482	17	lf	lf	PROPN
bptjm-16	482	18	,	,	PUNCT
bptjm-16	482	19	wang	wang	PROPN
bptjm-16	482	20	fs	fs	PROPN
bptjm-16	482	21	,	,	PUNCT
bptjm-16	482	22	wang	wang	PROPN
bptjm-16	482	23	x.	x.	PROPN
bptjm-16	482	24	mixed	mixed	PROPN
bptjm-16	482	25	lineage	lineage	PROPN
bptjm-16	482	26	kinase	kinase	NOUN
bptjm-16	482	27	domain	domain	NOUN
bptjm-16	482	28	like	like	ADP
bptjm-16	482	29	protein	protein	NOUN
bptjm-16	482	30	mlkl	mlkl	VERB
bptjm-16	482	31	causes	cause	VERB
bptjm-16	482	32	necrotic	necrotic	ADJ
bptjm-16	482	33	membrane	membrane	NOUN
bptjm-16	482	34	disruption	disruption	NOUN
bptjm-16	482	35	upon	upon	SCONJ
bptjm-16	482	36	phosphorylation	phosphorylation	NOUN
bptjm-16	482	37	by	by	ADP
bptjm-16	482	38	rip3.mol	rip3.mol	PROPN
bptjm-16	482	39	cell	cell	NOUN
bptjm-16	482	40	.	.	PUNCT
bptjm-16	483	1	2014	2014	NUM
bptjm-16	483	2	apr	apr	NOUN
bptjm-16	483	3	10	10	NUM
bptjm-16	483	4	;	;	PUNCT
bptjm-16	483	5	54(1):133	54(1):133	NUM
bptjm-16	483	6	-	-	SYM
bptjm-16	483	7	146	146	NUM
bptjm-16	483	8	.	.	PUNCT
bptjm-16	484	1	doi	doi	NOUN
bptjm-16	484	2	:	:	PUNCT
bptjm-16	484	3	10.1016	10.1016	NUM
bptjm-16	484	4	/	/	SYM
bptjm-16	484	5	j.molcel.2014.03.003	j.molcel.2014.03.003	PROPN
bptjm-16	484	6	.	.	PROPN
bptjm-16	484	7	67	67	NUM
bptjm-16	484	8	.	.	PUNCT
bptjm-16	485	1	wallach	wallach	PROPN
bptjm-16	485	2	d	d	PROPN
bptjm-16	485	3	,	,	PUNCT
bptjm-16	485	4	kang	kang	PROPN
bptjm-16	485	5	tb	tb	PROPN
bptjm-16	485	6	,	,	PUNCT
bptjm-16	485	7	kovalenko	kovalenko	ADJ
bptjm-16	485	8	a.	a.	NOUN
bptjm-16	485	9	concepts	concept	NOUN
bptjm-16	485	10	of	of	ADP
bptjm-16	485	11	tissue	tissue	NOUN
bptjm-16	485	12	injury	injury	NOUN
bptjm-16	485	13	and	and	CCONJ
bptjm-16	485	14	cell	cell	NOUN
bptjm-16	485	15	death	death	NOUN
bptjm-16	485	16	in	in	ADP
bptjm-16	485	17	in	in	ADP
bptjm-16	485	18	ammation	ammation	NOUN
bptjm-16	485	19	:	:	PUNCT
bptjm-16	485	20	a	a	DET
bptjm-16	485	21	historical	historical	ADJ
bptjm-16	485	22	perspective.nat	perspective.nat	NOUN
bptjm-16	485	23	rev	rev	X
bptjm-16	485	24	immunol	immunol	NOUN
bptjm-16	485	25	.	.	PUNCT
bptjm-16	486	1	2014	2014	NUM
bptjm-16	486	2	jan	jan	PROPN
bptjm-16	486	3	;	;	PUNCT
bptjm-16	486	4	14(1):51	14(1):51	NUM
bptjm-16	486	5	-	-	SYM
bptjm-16	486	6	9	9	NUM
bptjm-16	486	7	.	.	PUNCT
bptjm-16	486	8	doi	doi	NOUN
bptjm-16	486	9	:	:	PUNCT
bptjm-16	486	10	10.1038	10.1038	NUM
bptjm-16	486	11	/	/	SYM
bptjm-16	486	12	nri3561	nri3561	NOUN
bptjm-16	486	13	.	.	PUNCT
bptjm-16	487	1	68	68	NUM
bptjm-16	487	2	.	.	PUNCT
bptjm-16	488	1	pasparakis	pasparakis	PROPN
bptjm-16	488	2	m	m	PROPN
bptjm-16	488	3	,	,	PUNCT
bptjm-16	488	4	vandenabeele	vandenabeele	PROPN
bptjm-16	488	5	p.	p.	NOUN
bptjm-16	488	6	necroptosis	necroptosis	NOUN
bptjm-16	488	7	and	and	CCONJ
bptjm-16	488	8	its	its	PRON
bptjm-16	488	9	role	role	NOUN
bptjm-16	488	10	in	in	ADP
bptjm-16	488	11	in	in	ADP
bptjm-16	488	12	ammation.nature	ammation.nature	PROPN
bptjm-16	488	13	.	.	PUNCT
bptjm-16	489	1	2015	2015	NUM
bptjm-16	489	2	jan	jan	PROPN
bptjm-16	489	3	15	15	NUM
bptjm-16	489	4	;	;	PUNCT
bptjm-16	489	5	517(7534):311	517(7534):311	NUM
bptjm-16	489	6	-	-	SYM
bptjm-16	489	7	20	20	NUM
bptjm-16	489	8	.	.	PUNCT
bptjm-16	490	1	doi	doi	NOUN
bptjm-16	490	2	:	:	PUNCT
bptjm-16	490	3	10.1038	10.1038	NUM
bptjm-16	490	4	/	/	SYM
bptjm-16	490	5	nature14191	nature14191	PROPN
bptjm-16	490	6	.	.	PUNCT
bptjm-16	491	1	69	69	NUM
bptjm-16	491	2	.	.	PUNCT
bptjm-16	492	1	kang	kang	PROPN
bptjm-16	492	2	tb	tb	PROPN
bptjm-16	492	3	,	,	PUNCT
bptjm-16	492	4	yang	yang	PROPN
bptjm-16	492	5	sh	sh	PROPN
bptjm-16	492	6	,	,	PUNCT
bptjm-16	492	7	toth	toth	PROPN
bptjm-16	492	8	b	b	PROPN
bptjm-16	492	9	,	,	PUNCT
bptjm-16	492	10	kovalenko	kovalenko	PROPN
bptjm-16	492	11	a	a	PRON
bptjm-16	492	12	,	,	PUNCT
bptjm-16	492	13	wallach	wallach	PROPN
bptjm-16	492	14	d.	d.	PROPN
bptjm-16	492	15	caspase-8	caspase-8	PROPN
bptjm-16	492	16	blocks	block	VERB
bptjm-16	492	17	kinase	kinase	PROPN
bptjm-16	492	18	ripk3	ripk3	PROPN
bptjm-16	492	19	-	-	PUNCT
bptjm-16	492	20	mediated	mediate	VERB
bptjm-16	492	21	activation	activation	NOUN
bptjm-16	492	22	of	of	ADP
bptjm-16	492	23	the	the	DET
bptjm-16	492	24	nlrp3	nlrp3	NOUN
bptjm-16	492	25	in	in	ADP
bptjm-16	492	26	ammasome	ammasome	NOUN
bptjm-16	492	27	.	.	PUNCT
bptjm-16	493	1	immunity	immunity	NOUN
bptjm-16	493	2	.	.	PUNCT
bptjm-16	494	1	2013	2013	NUM
bptjm-16	494	2	jan	jan	PROPN
bptjm-16	494	3	24	24	NUM
bptjm-16	494	4	;	;	PUNCT
bptjm-16	494	5	3	3	NUM
bptjm-16	494	6	8(1):27	8(1):27	NUM
bptjm-16	494	7	-	-	SYM
bptjm-16	494	8	40	40	NUM
bptjm-16	494	9	.	.	PUNCT
bptjm-16	495	1	doi	doi	NOUN
bptjm-16	495	2	:	:	PUNCT
bptjm-16	495	3	10.1016	10.1016	NUM
bptjm-16	495	4	/	/	SYM
bptjm-16	495	5	j.immuni.2012.09.015	j.immuni.2012.09.015	PROPN
bptjm-16	495	6	.	.	PROPN
bptjm-16	496	1	70	70	NUM
bptjm-16	496	2	.	.	PUNCT
bptjm-16	497	1	lawlor	lawlor	PROPN
bptjm-16	497	2	ke	ke	PROPN
bptjm-16	497	3	,	,	PUNCT
bptjm-16	497	4	khan	khan	PROPN
bptjm-16	497	5	n	n	CCONJ
bptjm-16	497	6	,	,	PUNCT
bptjm-16	497	7	mildenhall	mildenhall	NOUN
bptjm-16	497	8	a	a	PRON
bptjm-16	497	9	,	,	PUNCT
bptjm-16	497	10	gerlic	gerlic	PROPN
bptjm-16	497	11	m	m	PROPN
bptjm-16	497	12	,	,	PUNCT
bptjm-16	497	13	croker	croker	PROPN
bptjm-16	497	14	ba	ba	PROPN
bptjm-16	497	15	,	,	PUNCT
bptjm-16	497	16	d'cruz	d'cruz	PROPN
bptjm-16	497	17	aa	aa	PROPN
bptjm-16	497	18	,	,	PUNCT
bptjm-16	497	19	hall	hall	PROPN
bptjm-16	497	20	c	c	PROPN
bptjm-16	497	21	,	,	PUNCT
bptjm-16	497	22	kaur	kaur	PROPN
bptjm-16	497	23	spall	spall	PROPN
bptjm-16	497	24	s	s	PROPN
bptjm-16	497	25	,	,	PUNCT
bptjm-16	497	26	anderton	anderton	PROPN
bptjm-16	497	27	h	h	PROPN
bptjm-16	497	28	,	,	PUNCT
bptjm-16	497	29	masters	master	NOUN
bptjm-16	497	30	sl	sl	NOUN
bptjm-16	497	31	,	,	PUNCT
bptjm-16	497	32	rashidi	rashidi	PROPN
bptjm-16	497	33	m	m	PROPN
bptjm-16	497	34	,	,	PUNCT
bptjm-16	497	35	berkeley	berkeley	PROPN
bptjm-16	497	36	pharma	pharma	PROPN
bptjm-16	497	37	tech	tech	NOUN
bptjm-16	497	38	journal	journal	NOUN
bptjm-16	497	39	of	of	ADP
bptjm-16	497	40	medicine	medicine	NOUN
bptjm-16	497	41	|	|	ADV
bptjm-16	497	42	114	114	NUM
bptjm-16	497	43	wicks	wick	NOUN
bptjm-16	497	44	ip	ip	NOUN
bptjm-16	497	45	,	,	PUNCT
bptjm-16	497	46	alexander	alexander	PROPN
bptjm-16	497	47	ws	ws	PROPN
bptjm-16	497	48	,	,	PUNCT
bptjm-16	497	49	mitsuuchi	mitsuuchi	PROPN
bptjm-16	497	50	y	y	PROPN
bptjm-16	497	51	,	,	PUNCT
bptjm-16	497	52	benetatos	benetato	NOUN
bptjm-16	497	53	ca	can	AUX
bptjm-16	497	54	,	,	PUNCT
bptjm-16	497	55	condon	condon	PROPN
bptjm-16	497	56	sm	sm	PROPN
bptjm-16	497	57	,	,	PUNCT
bptjm-16	497	58	wong	wong	PROPN
bptjm-16	497	59	ww	ww	PROPN
bptjm-16	497	60	,	,	PUNCT
bptjm-16	497	61	silke	silke	PROPN
bptjm-16	497	62	j	j	PROPN
bptjm-16	497	63	,	,	PUNCT
bptjm-16	497	64	vaux	vaux	PROPN
bptjm-16	497	65	dl	dl	PROPN
bptjm-16	497	66	,	,	PUNCT
bptjm-16	497	67	vince	vince	PROPN
bptjm-16	497	68	je	je	PROPN
bptjm-16	497	69	.	.	PUNCT
bptjm-16	498	1	ripk3	ripk3	PROPN
bptjm-16	498	2	promotes	promote	VERB
bptjm-16	498	3	cell	cell	NOUN
bptjm-16	498	4	death	death	NOUN
bptjm-16	498	5	and	and	CCONJ
bptjm-16	498	6	nlrp3	nlrp3	NOUN
bptjm-16	498	7	in	in	ADP
bptjm-16	498	8	ammasome	ammasome	ADJ
bptjm-16	498	9	activation	activation	NOUN
bptjm-16	498	10	in	in	ADP
bptjm-16	498	11	the	the	DET
bptjm-16	498	12	absence	absence	NOUN
bptjm-16	498	13	of	of	ADP
bptjm-16	498	14	mlkl.nat	mlkl.nat	X
bptjm-16	498	15	commun	commun	X
bptjm-16	498	16	.	.	PUNCT
bptjm-16	499	1	2015	2015	NUM
bptjm-16	499	2	feb	feb	NOUN
bptjm-16	499	3	18	18	NUM
bptjm-16	499	4	;	;	PUNCT
bptjm-16	499	5	6:6282	6:6282	NUM
bptjm-16	499	6	.	.	PUNCT
bptjm-16	499	7	doi	doi	NOUN
bptjm-16	499	8	:	:	PUNCT
bptjm-16	499	9	10.1038	10.1038	NUM
bptjm-16	499	10	/	/	SYM
bptjm-16	499	11	ncomms7282	ncomms7282	PROPN
bptjm-16	499	12	.	.	PUNCT
bptjm-16	500	1	71	71	NUM
bptjm-16	500	2	.	.	PUNCT
bptjm-16	501	1	chi	chi	PROPN
bptjm-16	501	2	h.	h.	PROPN
bptjm-16	501	3	,	,	PUNCT
bptjm-16	501	4	chang	chang	PROPN
bptjm-16	501	5	h.y	h.y	PROPN
bptjm-16	501	6	.	.	PROPN
bptjm-16	501	7	,	,	PUNCT
bptjm-16	501	8	sang	sing	VERB
bptjm-16	501	9	t.k	t.k	PROPN
bptjm-16	501	10	.	.	NOUN
bptjm-16	501	11	neuronal	neuronal	ADJ
bptjm-16	501	12	cell	cell	NOUN
bptjm-16	501	13	death	death	NOUN
bptjm-16	501	14	mechanisms	mechanism	NOUN
bptjm-16	501	15	in	in	ADP
bptjm-16	501	16	major	major	ADJ
bptjm-16	501	17	neurodegenerative	neurodegenerative	ADJ
bptjm-16	501	18	diseases	disease	NOUN
bptjm-16	501	19	.	.	PUNCT
bptjm-16	502	1	int	int	NOUN
bptjm-16	502	2	.	.	PUNCT
bptjm-16	503	1	j.	j.	PROPN
bptjm-16	503	2	mol	mol	PROPN
bptjm-16	503	3	.	.	PUNCT
bptjm-16	504	1	sci	sci	PROPN
bptjm-16	504	2	.	.	PROPN
bptjm-16	504	3	2018	2018	NUM
bptjm-16	504	4	;	;	PUNCT
bptjm-16	504	5	19:3082	19:3082	NUM
bptjm-16	504	6	.	.	X
bptjm-16	505	1	doi	doi	NOUN
bptjm-16	505	2	:	:	PUNCT
bptjm-16	505	3	10.3390	10.3390	NUM
bptjm-16	505	4	/	/	SYM
bptjm-16	505	5	ijms19103082	ijms19103082	PROPN
bptjm-16	505	6	72	72	NUM
bptjm-16	505	7	.	.	PUNCT
bptjm-16	506	1	ofengeim	ofengeim	PROPN
bptjm-16	506	2	d.	d.	PROPN
bptjm-16	506	3	,	,	PUNCT
bptjm-16	506	4	mazzitelli	mazzitelli	PROPN
bptjm-16	506	5	s.	s.	PROPN
bptjm-16	506	6	,	,	PUNCT
bptjm-16	506	7	ito	ito	PROPN
bptjm-16	506	8	y.	y.	PROPN
bptjm-16	506	9	,	,	PUNCT
bptjm-16	506	10	dewitt	dewitt	PROPN
bptjm-16	506	11	j.p	j.p	PROPN
bptjm-16	506	12	.	.	PROPN
bptjm-16	506	13	,	,	PUNCT
bptjm-16	506	14	mi	mi	PROPN
bptjm-16	506	15	in	in	ADP
bptjm-16	506	16	l.	l.	PROPN
bptjm-16	506	17	,	,	PUNCT
bptjm-16	506	18	zou	zou	PROPN
bptjm-16	506	19	c.	c.	PROPN
bptjm-16	506	20	,	,	PUNCT
bptjm-16	506	21	das	das	PROPN
bptjm-16	506	22	s.	s.	PROPN
bptjm-16	506	23	,	,	PUNCT
bptjm-16	506	24	adiconis	adiconis	PROPN
bptjm-16	506	25	x.	x.	PROPN
bptjm-16	506	26	,	,	PUNCT
bptjm-16	506	27	chen	chen	PROPN
bptjm-16	506	28	h.	h.	PROPN
bptjm-16	506	29	,	,	PUNCT
bptjm-16	506	30	zhu	zhu	PROPN
bptjm-16	506	31	h.	h.	PROPN
bptjm-16	506	32	,	,	PUNCT
bptjm-16	506	33	et	et	PROPN
bptjm-16	506	34	al	al	PROPN
bptjm-16	506	35	.	.	PUNCT
bptjm-16	507	1	ripk1	ripk1	PROPN
bptjm-16	507	2	mediates	mediate	VERB
bptjm-16	507	3	a	a	DET
bptjm-16	507	4	disease	disease	NOUN
bptjm-16	507	5	-	-	PUNCT
bptjm-16	507	6	associated	associate	VERB
bptjm-16	507	7	microglial	microglial	ADJ
bptjm-16	507	8	response	response	NOUN
bptjm-16	507	9	in	in	ADP
bptjm-16	507	10	alzheimer	alzheimer	PROPN
bptjm-16	507	11	’s	’s	PART
bptjm-16	507	12	disease	disease	NOUN
bptjm-16	507	13	.	.	PUNCT
bptjm-16	508	1	proc	proc	NOUN
bptjm-16	508	2	.	.	PUNCT
bptjm-16	509	1	natl.acad	natl.acad	PROPN
bptjm-16	509	2	.	.	PUNCT
bptjm-16	509	3	sci	sci	PROPN
bptjm-16	509	4	.	.	PROPN
bptjm-16	509	5	usa	usa	PROPN
bptjm-16	509	6	.	.	PROPN
bptjm-16	509	7	2017	2017	NUM
bptjm-16	509	8	;	;	PUNCT
bptjm-16	509	9	114	114	NUM
bptjm-16	509	10	:	:	PUNCT
bptjm-16	509	11	e8788	e8788	PROPN
bptjm-16	509	12	–	–	PUNCT
bptjm-16	509	13	e8797	e8797	NOUN
bptjm-16	509	14	.	.	PUNCT
bptjm-16	510	1	doi:10.1073/	doi:10.1073/	PROPN
bptjm-16	510	2	pnas.1714175114	pnas.1714175114	PROPN
bptjm-16	510	3	73	73	NUM
bptjm-16	510	4	.	.	PUNCT
bptjm-16	511	1	caccamo	caccamo	PROPN
bptjm-16	511	2	a.	a.	PROPN
bptjm-16	511	3	,	,	PUNCT
bptjm-16	511	4	branca	branca	PROPN
bptjm-16	511	5	c.	c.	PROPN
bptjm-16	511	6	,	,	PUNCT
bptjm-16	511	7	piras	piras	PROPN
bptjm-16	511	8	i.s	i.s	PROPN
bptjm-16	511	9	.	.	PROPN
bptjm-16	511	10	,	,	PUNCT
bptjm-16	511	11	ferreira	ferreira	PROPN
bptjm-16	511	12	e.	e.	PROPN
bptjm-16	511	13	,	,	PUNCT
bptjm-16	511	14	huentelman	huentelman	PROPN
bptjm-16	511	15	m.j	m.j	PROPN
bptjm-16	511	16	.	.	PROPN
bptjm-16	511	17	,	,	PUNCT
bptjm-16	511	18	liang	liang	PROPN
bptjm-16	511	19	w.s	w.s	PROPN
bptjm-16	511	20	.	.	PROPN
bptjm-16	511	21	,	,	PUNCT
bptjm-16	511	22	readheadb	readheadb	PROPN
bptjm-16	511	23	.	.	PUNCT
bptjm-16	511	24	,	,	PUNCT
bptjm-16	511	25	dudley	dudley	PROPN
bptjm-16	511	26	j.t	j.t	PROPN
bptjm-16	511	27	.	.	PROPN
bptjm-16	511	28	,	,	PUNCT
bptjm-16	511	29	spangenberg	spangenberg	PROPN
bptjm-16	511	30	e.e	e.e	PROPN
bptjm-16	511	31	.	.	PROPN
bptjm-16	511	32	,	,	PUNCT
bptjm-16	511	33	green	green	PROPN
bptjm-16	511	34	k.n	k.n	PROPN
bptjm-16	511	35	.	.	PROPN
bptjm-16	511	36	,	,	PUNCT
bptjm-16	511	37	et	et	PROPN
bptjm-16	511	38	al	al	PROPN
bptjm-16	511	39	.	.	PROPN
bptjm-16	511	40	necroptosis	necroptosis	NOUN
bptjm-16	511	41	activation	activation	NOUN
bptjm-16	511	42	in	in	ADP
bptjm-16	511	43	alzheimer	alzheimer	PROPN
bptjm-16	511	44	’s	’s	PART
bptjm-16	511	45	disease	disease	NOUN
bptjm-16	511	46	.	.	PUNCT
bptjm-16	512	1	nat	nat	PROPN
bptjm-16	512	2	.	.	PUNCT
bptjm-16	513	1	neurosci	neurosci	PROPN
bptjm-16	513	2	.	.	PUNCT
bptjm-16	514	1	2017	2017	NUM
bptjm-16	514	2	;	;	PUNCT
bptjm-16	514	3	20:1236–1246	20:1236–1246	NUM
bptjm-16	514	4	.	.	PUNCT
bptjm-16	515	1	doi	doi	NOUN
bptjm-16	515	2	:	:	PUNCT
bptjm-16	515	3	10.1038	10.1038	NUM
bptjm-16	515	4	/	/	SYM
bptjm-16	515	5	nn.4608	nn.4608	PROPN
bptjm-16	515	6	74	74	NUM
bptjm-16	515	7	.	.	PUNCT
bptjm-16	516	1	lee	lee	PROPN
bptjm-16	516	2	s.h	s.h	PROPN
bptjm-16	516	3	.	.	PROPN
bptjm-16	516	4	,	,	PUNCT
bptjm-16	516	5	kwon	kwon	PROPN
bptjm-16	516	6	j.y	j.y	PROPN
bptjm-16	516	7	.	.	PROPN
bptjm-16	516	8	,	,	PUNCT
bptjm-16	516	9	kim	kim	PROPN
bptjm-16	516	10	s.y	s.y	PROPN
bptjm-16	516	11	.	.	PROPN
bptjm-16	516	12	,	,	PUNCT
bptjm-16	516	13	jung	jung	PROPN
bptjm-16	516	14	k.	k.	PROPN
bptjm-16	516	15	,	,	PUNCT
bptjm-16	516	16	cho	cho	PROPN
bptjm-16	516	17	m.l	m.l	PROPN
bptjm-16	516	18	.	.	PROPN
bptjm-16	516	19	interferon	interferon	PROPN
bptjm-16	516	20	-	-	PUNCT
bptjm-16	516	21	gamma	gamma	NOUN
bptjm-16	516	22	regulates	regulate	VERB
bptjm-16	516	23	in	in	ADP
bptjm-16	516	24	ammatory	ammatory	ADJ
bptjm-16	516	25	cell	cell	NOUN
bptjm-16	516	26	death	death	NOUN
bptjm-16	516	27	by	by	ADP
bptjm-16	516	28	targeting	target	VERB
bptjm-16	516	29	necroptosis	necroptosis	NOUN
bptjm-16	516	30	in	in	ADP
bptjm-16	516	31	experimental	experimental	ADJ
bptjm-16	516	32	autoimmune	autoimmune	ADJ
bptjm-16	516	33	arthritis	arthritis	NOUN
bptjm-16	516	34	.	.	PUNCT
bptjm-16	517	1	sci	sci	PROPN
bptjm-16	517	2	.	.	PROPN
bptjm-16	517	3	rep	rep	PROPN
bptjm-16	517	4	.	.	PROPN
bptjm-16	517	5	2017	2017	NUM
bptjm-16	517	6	;	;	PUNCT
bptjm-16	517	7	7:10133	7:10133	X
bptjm-16	517	8	.	.	X
bptjm-16	518	1	doi	doi	NOUN
bptjm-16	518	2	:	:	PUNCT
bptjm-16	518	3	10.1038	10.1038	NUM
bptjm-16	518	4	/	/	SYM
bptjm-16	518	5	s41598	s41598	NOUN
bptjm-16	518	6	-	-	PUNCT
bptjm-16	518	7	017	017	NUM
bptjm-16	518	8	-	-	PUNCT
bptjm-16	518	9	09767	09767	NUM
bptjm-16	518	10	-	-	SYM
bptjm-16	518	11	0	0	NUM
bptjm-16	518	12	75	75	NUM
bptjm-16	518	13	.	.	PUNCT
bptjm-16	519	1	bertrand	bertrand	PROPN
bptjm-16	519	2	m.	m.	PROPN
bptjm-16	519	3	,	,	PUNCT
bptjm-16	519	4	doiron	doiron	PROPN
bptjm-16	519	5	k.	k.	PROPN
bptjm-16	519	6	,	,	PUNCT
bptjm-16	519	7	labbe	labbe	PROPN
bptjm-16	519	8	k.	k.	PROPN
bptjm-16	519	9	,	,	PUNCT
bptjm-16	519	10	korneluk	korneluk	PROPN
bptjm-16	519	11	r.	r.	PROPN
bptjm-16	519	12	,	,	PUNCT
bptjm-16	519	13	barker	barker	PROPN
bptjm-16	519	14	p.	p.	PROPN
bptjm-16	519	15	,	,	PUNCT
bptjm-16	519	16	saleh	saleh	PROPN
bptjm-16	519	17	m.	m.	NOUN
bptjm-16	519	18	cellular	cellular	ADJ
bptjm-16	519	19	inhibitors	inhibitor	NOUN
bptjm-16	519	20	of	of	ADP
bptjm-16	519	21	apoptosis	apoptosis	NOUN
bptjm-16	519	22	ciap1	ciap1	NOUN
bptjm-16	519	23	and	and	CCONJ
bptjm-16	519	24	ciap2	ciap2	NOUN
bptjm-16	519	25	are	be	AUX
bptjm-16	519	26	required	require	VERB
bptjm-16	519	27	for	for	ADP
bptjm-16	519	28	innate	innate	ADJ
bptjm-16	519	29	immunity	immunity	NOUN
bptjm-16	519	30	signaling	signal	VERB
bptjm-16	519	31	by	by	ADP
bptjm-16	519	32	the	the	DET
bptjm-16	519	33	pattern	pattern	NOUN
bptjm-16	519	34	recognition	recognition	NOUN
bptjm-16	519	35	receptors	receptor	NOUN
bptjm-16	519	36	nod1	nod1	NOUN
bptjm-16	519	37	and	and	CCONJ
bptjm-16	519	38	nod2	nod2	NOUN
bptjm-16	519	39	.	.	PUNCT
bptjm-16	520	1	cell	cell	NOUN
bptjm-16	520	2	.	.	PUNCT
bptjm-16	521	1	2009	2009	NUM
bptjm-16	521	2	;	;	PUNCT
bptjm-16	521	3	789	789	NUM
bptjm-16	521	4	-	-	SYM
bptjm-16	521	5	801	801	NUM
bptjm-16	521	6	.	.	PUNCT
bptjm-16	521	7	doi:10.1016	doi:10.1016	PROPN
bptjm-16	521	8	/	/	SYM
bptjm-16	521	9	j.immuni.20	j.immuni.20	PROPN
bptjm-16	521	10	9.04.011	9.04.011	PROPN
bptjm-16	521	11	76	76	NUM
bptjm-16	521	12	.	.	PUNCT
bptjm-16	522	1	schimmer	schimmer	NOUN
bptjm-16	522	2	ad	ad	NOUN
bptjm-16	522	3	.	.	PUNCT
bptjm-16	523	1	inhibitor	inhibitor	NOUN
bptjm-16	523	2	of	of	ADP
bptjm-16	523	3	apoptosis	apoptosis	NOUN
bptjm-16	523	4	proteins	protein	NOUN
bptjm-16	523	5	:	:	PUNCT
bptjm-16	523	6	translating	translate	VERB
bptjm-16	523	7	basic	basic	ADJ
bptjm-16	523	8	knowledge	knowledge	NOUN
bptjm-16	523	9	into	into	ADP
bptjm-16	523	10	clinical	clinical	ADJ
bptjm-16	523	11	practice	practice	NOUN
bptjm-16	523	12	.	.	PUNCT
bptjm-16	524	1	cancer	cancer	NOUN
bptjm-16	524	2	research	research	NOUN
bptjm-16	524	3	.	.	PUNCT
bptjm-16	525	1	2004	2004	NUM
bptjm-16	525	2	;	;	PUNCT
bptjm-16	525	3	64(20):7183	64(20):7183	X
bptjm-16	525	4	-	-	SYM
bptjm-16	525	5	7190	7190	NUM
bptjm-16	525	6	.	.	PUNCT
bptjm-16	526	1	doi:10.1158/0008	doi:10.1158/0008	NOUN
bptjm-16	526	2	-	-	PUNCT
bptjm-16	526	3	5472.can-04	5472.can-04	NUM
bptjm-16	526	4	-	-	PUNCT
bptjm-16	526	5	1918	1918	NUM
bptjm-16	526	6	77	77	NUM
bptjm-16	526	7	.	.	PUNCT
bptjm-16	527	1	yang	yang	PROPN
bptjm-16	527	2	s	s	PROPN
bptjm-16	527	3	,	,	PUNCT
bptjm-16	527	4	wang	wang	PROPN
bptjm-16	527	5	j	j	PROPN
bptjm-16	527	6	,	,	PUNCT
bptjm-16	527	7	brand	brand	PROPN
bptjm-16	527	8	dd	dd	PROPN
bptjm-16	527	9	,	,	PUNCT
bptjm-16	527	10	zheng	zheng	PROPN
bptjm-16	527	11	sg	sg	PROPN
bptjm-16	527	12	.	.	PUNCT
bptjm-16	527	13	role	role	NOUN
bptjm-16	527	14	of	of	ADP
bptjm-16	527	15	tnf	tnf	PROPN
bptjm-16	527	16	–	–	PUNCT
bptjm-16	527	17	tnf	tnf	PROPN
bptjm-16	527	18	receptor	receptor	NOUN
bptjm-16	527	19	2	2	NUM
bptjm-16	527	20	signal	signal	NOUN
bptjm-16	527	21	in	in	ADP
bptjm-16	527	22	regulatory	regulatory	ADJ
bptjm-16	527	23	t	t	NOUN
bptjm-16	527	24	cells	cell	NOUN
bptjm-16	527	25	and	and	CCONJ
bptjm-16	527	26	its	its	PRON
bptjm-16	527	27	therapeutic	therapeutic	ADJ
bptjm-16	527	28	implications	implication	NOUN
bptjm-16	527	29	.	.	PUNCT
bptjm-16	528	1	frontiers	frontier	NOUN
bptjm-16	528	2	in	in	ADP
bptjm-16	528	3	immunology	immunology	NOUN
bptjm-16	528	4	.	.	PUNCT
bptjm-16	529	1	2018	2018	NUM
bptjm-16	529	2	;	;	PUNCT
bptjm-16	529	3	9	9	NUM
bptjm-16	529	4	.	.	PUNCT
bptjm-16	530	1	doi:10.3389/	doi:10.3389/	NOUN
bptjm-16	530	2	mmu.2018.00784	mmu.2018.00784	ADP
bptjm-16	530	3	78	78	NUM
bptjm-16	530	4	.	.	PUNCT
bptjm-16	531	1	obexer	obexer	PROPN
bptjm-16	531	2	p	p	PROPN
bptjm-16	531	3	,	,	PUNCT
bptjm-16	531	4	ausserlechner	ausserlechner	PROPN
bptjm-16	531	5	mj	mj	PROPN
bptjm-16	531	6	.	.	PUNCT
bptjm-16	532	1	x	x	VERB
bptjm-16	532	2	-	-	VERB
bptjm-16	532	3	linked	link	VERB
bptjm-16	532	4	inhibitor	inhibitor	NOUN
bptjm-16	532	5	of	of	ADP
bptjm-16	532	6	apoptosis	apoptosis	NOUN
bptjm-16	532	7	protein	protein	NOUN
bptjm-16	532	8	a	a	DET
bptjm-16	532	9	critical	critical	ADJ
bptjm-16	532	10	death	death	NOUN
bptjm-16	532	11	resistance	resistance	NOUN
bptjm-16	532	12	regulator	regulator	NOUN
bptjm-16	532	13	and	and	CCONJ
bptjm-16	532	14	therapeutic	therapeutic	ADJ
bptjm-16	532	15	target	target	NOUN
bptjm-16	532	16	for	for	ADP
bptjm-16	532	17	personalized	personalized	ADJ
bptjm-16	532	18	cancer	cancer	NOUN
bptjm-16	532	19	therapy	therapy	NOUN
bptjm-16	532	20	.	.	PUNCT
bptjm-16	533	1	frontiers	frontier	NOUN
bptjm-16	533	2	in	in	ADP
bptjm-16	533	3	oncology	oncology	NOUN
bptjm-16	533	4	.	.	PUNCT
bptjm-16	534	1	2014	2014	NUM
bptjm-16	534	2	;	;	PUNCT
bptjm-16	534	3	4	4	X
bptjm-16	534	4	.	.	X
bptjm-16	534	5	doi:10.3389	doi:10.3389	PROPN
bptjm-16	534	6	/	/	SYM
bptjm-16	534	7	fonc.2014.00197	fonc.2014.00197	PROPN
bptjm-16	534	8	79	79	NUM
bptjm-16	534	9	.	.	PUNCT
bptjm-16	535	1	vasilikos	vasilikos	PROPN
bptjm-16	535	2	l	l	PROPN
bptjm-16	535	3	,	,	PUNCT
bptjm-16	535	4	spilgies	spilgie	NOUN
bptjm-16	535	5	lm	lm	PROPN
bptjm-16	535	6	,	,	PUNCT
bptjm-16	535	7	knop	knop	PROPN
bptjm-16	535	8	j	j	PROPN
bptjm-16	535	9	,	,	PUNCT
bptjm-16	535	10	wong	wong	PROPN
bptjm-16	535	11	wwl	wwl	PROPN
bptjm-16	535	12	.	.	PUNCT
bptjm-16	536	1	regulating	regulate	VERB
bptjm-16	536	2	the	the	DET
bptjm-16	536	3	balance	balance	NOUN
bptjm-16	536	4	between	between	ADP
bptjm-16	536	5	necroptosis	necroptosis	NOUN
bptjm-16	536	6	,	,	PUNCT
bptjm-16	536	7	apoptosis	apoptosis	NOUN
bptjm-16	536	8	and	and	CCONJ
bptjm-16	536	9	in	in	ADP
bptjm-16	536	10	ammation	ammation	NOUN
bptjm-16	536	11	by	by	ADP
bptjm-16	536	12	inhibitors	inhibitor	NOUN
bptjm-16	536	13	of	of	ADP
bptjm-16	536	14	apoptosis	apoptosis	NOUN
bptjm-16	536	15	proteins	protein	NOUN
bptjm-16	536	16	.	.	PUNCT
bptjm-16	537	1	immunology	immunology	NOUN
bptjm-16	537	2	&	&	CCONJ
bptjm-16	537	3	cell	cell	NOUN
bptjm-16	537	4	biology	biology	NOUN
bptjm-16	537	5	.	.	PUNCT
bptjm-16	538	1	2017	2017	NUM
bptjm-16	538	2	;	;	PUNCT
bptjm-16	538	3	95(2):160	95(2):160	NUM
bptjm-16	538	4	-	-	SYM
bptjm-16	538	5	165	165	NUM
bptjm-16	538	6	.	.	PUNCT
bptjm-16	538	7	doi:10.1038	doi:10.1038	NOUN
bptjm-16	538	8	/	/	SYM
bptjm-16	538	9	icb.2016.118	icb.2016.118	PROPN
bptjm-16	538	10	80	80	NUM
bptjm-16	538	11	.	.	PUNCT
bptjm-16	539	1	kasof	kasof	PROPN
bptjm-16	539	2	gm	gm	PROPN
bptjm-16	539	3	,	,	PUNCT
bptjm-16	539	4	gomes	gomes	PROPN
bptjm-16	539	5	bc	bc	PROPN
bptjm-16	539	6	:	:	PUNCT
bptjm-16	539	7	livin	livin	PROPN
bptjm-16	539	8	,	,	PUNCT
bptjm-16	539	9	a	a	DET
bptjm-16	539	10	novel	novel	ADJ
bptjm-16	539	11	inhibitor	inhibitor	NOUN
bptjm-16	539	12	of	of	ADP
bptjm-16	539	13	apoptosis	apoptosis	NOUN
bptjm-16	539	14	protein	protein	NOUN
bptjm-16	539	15	family	family	NOUN
bptjm-16	539	16	member	member	NOUN
bptjm-16	539	17	.	.	PUNCT
bptjm-16	540	1	j	j	PROPN
bptjm-16	540	2	biol	biol	PROPN
bptjm-16	540	3	chem	chem	NOUN
bptjm-16	540	4	.	.	PUNCT
bptjm-16	541	1	2001	2001	NUM
bptjm-16	541	2	;	;	PUNCT
bptjm-16	542	1	276:3238	276:3238	PROPN
bptjm-16	542	2	-	-	NOUN
bptjm-16	542	3	3246	3246	NUM
bptjm-16	542	4	.	.	PUNCT
bptjm-16	543	1	10.1074	10.1074	NUM
bptjm-16	543	2	/	/	SYM
bptjm-16	543	3	jbc.m003670200	jbc.m003670200	NOUN
bptjm-16	543	4	.	.	PUNCT
bptjm-16	544	1	81	81	NUM
bptjm-16	544	2	.	.	PUNCT
bptjm-16	545	1	lin	lin	PROPN
bptjm-16	545	2	jh	jh	PROPN
bptjm-16	545	3	,	,	PUNCT
bptjm-16	545	4	deng	deng	PROPN
bptjm-16	545	5	g	g	PROPN
bptjm-16	545	6	,	,	PUNCT
bptjm-16	545	7	huang	huang	PROPN
bptjm-16	545	8	qh	qh	PROPN
bptjm-16	545	9	,	,	PUNCT
bptjm-16	545	10	morser	morser	PROPN
bptjm-16	545	11	j	j	PROPN
bptjm-16	545	12	:	:	PUNCT
bptjm-16	545	13	kiap	kiap	PROPN
bptjm-16	545	14	,	,	PUNCT
bptjm-16	545	15	a	a	DET
bptjm-16	545	16	novel	novel	ADJ
bptjm-16	545	17	member	member	NOUN
bptjm-16	545	18	of	of	ADP
bptjm-16	545	19	the	the	DET
bptjm-16	545	20	inhibitor	inhibitor	NOUN
bptjm-16	545	21	of	of	ADP
bptjm-16	545	22	apoptosis	apoptosis	NOUN
bptjm-16	545	23	protein	protein	NOUN
bptjm-16	545	24	family	family	NOUN
bptjm-16	545	25	.	.	PUNCT
bptjm-16	546	1	biochem	biochem	PROPN
bptjm-16	546	2	biophys	biophy	VERB
bptjm-16	546	3	res	re	NOUN
bptjm-16	546	4	comm	comm	NOUN
bptjm-16	546	5	.	.	PUNCT
bptjm-16	547	1	2000	2000	NUM
bptjm-16	547	2	,	,	PUNCT
bptjm-16	547	3	279:820	279:820	NOUN
bptjm-16	547	4	-	-	PUNCT
bptjm-16	547	5	831	831	NUM
bptjm-16	547	6	.	.	PUNCT
bptjm-16	548	1	10.1006/	10.1006/	NUM
bptjm-16	548	2	bbrc.2000.4027	bbrc.2000.4027	ADJ
bptjm-16	548	3	.	.	PUNCT
bptjm-16	549	1	82	82	NUM
bptjm-16	549	2	.	.	PUNCT
bptjm-16	550	1	vucic	vucic	PROPN
bptjm-16	550	2	d	d	PROPN
bptjm-16	550	3	,	,	PUNCT
bptjm-16	550	4	stennicke	stennicke	PROPN
bptjm-16	550	5	hr	hr	PROPN
bptjm-16	550	6	,	,	PUNCT
bptjm-16	550	7	pisabarro	pisabarro	PROPN
bptjm-16	550	8	mt	mt	PROPN
bptjm-16	550	9	,	,	PUNCT
bptjm-16	550	10	salvesen	salvesen	PROPN
bptjm-16	550	11	gs	gs	PROPN
bptjm-16	550	12	,	,	PUNCT
bptjm-16	550	13	dixit	dixit	PROPN
bptjm-16	550	14	vm	vm	PROPN
bptjm-16	550	15	:	:	PUNCT
bptjm-16	550	16	ml	ml	PROPN
bptjm-16	550	17	-	-	PUNCT
bptjm-16	550	18	iap	iap	PROPN
bptjm-16	550	19	,	,	PUNCT
bptjm-16	550	20	a	a	DET
bptjm-16	550	21	novel	novel	ADJ
bptjm-16	550	22	inhibitor	inhibitor	NOUN
bptjm-16	550	23	of	of	ADP
bptjm-16	550	24	apoptosis	apoptosis	NOUN
bptjm-16	550	25	that	that	PRON
bptjm-16	550	26	is	be	AUX
bptjm-16	550	27	preferentially	preferentially	ADV
bptjm-16	550	28	expressed	express	VERB
bptjm-16	550	29	in	in	ADP
bptjm-16	550	30	human	human	ADJ
bptjm-16	550	31	melanomas	melanomas	NOUN
bptjm-16	550	32	.	.	PUNCT
bptjm-16	551	1	curr	curr	PROPN
bptjm-16	551	2	biol	biol	PROPN
bptjm-16	551	3	.	.	PUNCT
bptjm-16	552	1	2000	2000	NUM
bptjm-16	552	2	,	,	PUNCT
bptjm-16	552	3	10:1359	10:1359	NUM
bptjm-16	552	4	-	-	SYM
bptjm-16	552	5	1366	1366	NUM
bptjm-16	552	6	.	.	PUNCT
bptjm-16	553	1	10.1016/	10.1016/	NUM
bptjm-16	553	2	s0960	s0960	ADP
bptjm-16	553	3	-	-	PUNCT
bptjm-16	553	4	9822(00)00781	9822(00)00781	NUM
bptjm-16	553	5	-	-	SYM
bptjm-16	553	6	8	8	NUM
bptjm-16	553	7	.	.	PUNCT
bptjm-16	553	8	berkeley	berkeley	PROPN
bptjm-16	553	9	pharma	pharma	PROPN
bptjm-16	553	10	tech	tech	PROPN
bptjm-16	553	11	journal	journal	NOUN
bptjm-16	553	12	of	of	ADP
bptjm-16	553	13	medicine	medicine	NOUN
bptjm-16	553	14	|	|	ADV
bptjm-16	553	15	115	115	NUM