id	sid	tid	token	lemma	pos
bptjm-29	1	1	berkeley	berkeley	PROPN
bptjm-29	1	2	pharma	pharma	PROPN
bptjm-29	1	3	tech	tech	NOUN
bptjm-29	1	4	journal	journal	NOUN
bptjm-29	1	5	of	of	ADP
bptjm-29	1	6	medicine	medicine	NOUN
bptjm-29	1	7	correspondence	correspondence	NOUN
bptjm-29	1	8	:	:	PUNCT
bptjm-29	1	9	tanviy@berkeley.edu	tanviy@berkeley.edu	PROPN
bptjm-29	1	10	keywords	keyword	NOUN
bptjm-29	1	11	:	:	PUNCT
bptjm-29	1	12	amyotrophic	amyotrophic	ADJ
bptjm-29	1	13	lateral	lateral	ADJ
bptjm-29	1	14	sclerosis	sclerosis	NOUN
bptjm-29	1	15	pathogenesis	pathogenesis	NOUN
bptjm-29	1	16	of	of	ADP
bptjm-29	1	17	als	als	NOUN
bptjm-29	1	18	mesenchymal	mesenchymal	NOUN
bptjm-29	1	19	stem	stem	NOUN
bptjm-29	1	20	cells	cell	NOUN
bptjm-29	1	21	neurodegenerative	neurodegenerative	ADJ
bptjm-29	1	22	disease	disease	NOUN
bptjm-29	1	23	sod1	sod1	ADJ
bptjm-29	1	24	riluzole	riluzole	NOUN
bptjm-29	1	25	astrocytes	astrocyte	NOUN
bptjm-29	1	26	submitted	submit	VERB
bptjm-29	1	27	:	:	PUNCT
bptjm-29	1	28	august	august	PROPN
bptjm-29	1	29	12	12	NUM
bptjm-29	1	30	,	,	PUNCT
bptjm-29	1	31	2022	2022	NUM
bptjm-29	1	32	accepted	accept	VERB
bptjm-29	1	33	:	:	PUNCT
bptjm-29	1	34	october	october	PROPN
bptjm-29	1	35	24	24	NUM
bptjm-29	1	36	,	,	PUNCT
bptjm-29	1	37	2022	2022	NUM
bptjm-29	1	38	published	publish	VERB
bptjm-29	1	39	:	:	PUNCT
bptjm-29	1	40	december	december	PROPN
bptjm-29	1	41	28	28	NUM
bptjm-29	1	42	,	,	PUNCT
bptjm-29	1	43	2022	2022	NUM
bptjm-29	1	44	full	full	ADJ
bptjm-29	1	45	open	open	ADJ
bptjm-29	1	46	access	access	NOUN
bptjm-29	1	47	creative	creative	ADJ
bptjm-29	1	48	commons	common	NOUN
bptjm-29	1	49	attribution	attribution	NOUN
bptjm-29	1	50	license	license	VERB
bptjm-29	1	51	4.0	4.0	NUM
bptjm-29	1	52	abstract	abstract	ADJ
bptjm-29	1	53	amyotrophic	amyotrophic	ADJ
bptjm-29	1	54	lateral	lateral	ADJ
bptjm-29	1	55	sclerosis	sclerosis	NOUN
bptjm-29	1	56	(	(	PUNCT
bptjm-29	1	57	als	als	NOUN
bptjm-29	1	58	)	)	PUNCT
bptjm-29	1	59	is	be	AUX
bptjm-29	1	60	a	a	DET
bptjm-29	1	61	neurodegenerative	neurodegenerative	ADJ
bptjm-29	1	62	disease	disease	NOUN
bptjm-29	1	63	caused	cause	VERB
bptjm-29	1	64	by	by	ADP
bptjm-29	1	65	the	the	DET
bptjm-29	1	66	degeneration	degeneration	NOUN
bptjm-29	1	67	of	of	ADP
bptjm-29	1	68	motor	motor	NOUN
bptjm-29	1	69	neurons	neuron	NOUN
bptjm-29	1	70	in	in	ADP
bptjm-29	1	71	the	the	DET
bptjm-29	1	72	brain	brain	NOUN
bptjm-29	1	73	and	and	CCONJ
bptjm-29	1	74	spinal	spinal	NOUN
bptjm-29	1	75	cord	cord	NOUN
bptjm-29	1	76	,	,	PUNCT
bptjm-29	1	77	leading	lead	VERB
bptjm-29	1	78	to	to	ADP
bptjm-29	1	79	muscle	muscle	NOUN
bptjm-29	1	80	weakness	weakness	NOUN
bptjm-29	1	81	,	,	PUNCT
bptjm-29	1	82	paralysis	paralysis	NOUN
bptjm-29	1	83	,	,	PUNCT
bptjm-29	1	84	and	and	CCONJ
bptjm-29	1	85	eventually	eventually	ADV
bptjm-29	1	86	death	death	NOUN
bptjm-29	1	87	.	.	PUNCT
bptjm-29	2	1	exactly	exactly	ADV
bptjm-29	2	2	how	how	SCONJ
bptjm-29	2	3	and	and	CCONJ
bptjm-29	2	4	why	why	SCONJ
bptjm-29	2	5	motor	motor	NOUN
bptjm-29	2	6	neurons	neuron	NOUN
bptjm-29	2	7	degenerate	degenerate	VERB
bptjm-29	2	8	is	be	AUX
bptjm-29	2	9	still	still	ADV
bptjm-29	2	10	not	not	PART
bptjm-29	2	11	clearly	clearly	ADV
bptjm-29	2	12	known	know	VERB
bptjm-29	2	13	,	,	PUNCT
bptjm-29	2	14	but	but	CCONJ
bptjm-29	2	15	certain	certain	ADJ
bptjm-29	2	16	pathogenetic	pathogenetic	ADJ
bptjm-29	2	17	mechanisms	mechanism	NOUN
bptjm-29	2	18	could	could	AUX
bptjm-29	2	19	explain	explain	VERB
bptjm-29	2	20	the	the	DET
bptjm-29	2	21	process	process	NOUN
bptjm-29	2	22	.	.	PUNCT
bptjm-29	3	1	current	current	ADJ
bptjm-29	3	2	treatments	treatment	NOUN
bptjm-29	3	3	and	and	CCONJ
bptjm-29	3	4	interventions	intervention	NOUN
bptjm-29	3	5	,	,	PUNCT
bptjm-29	3	6	including	include	VERB
bptjm-29	3	7	pharmacological	pharmacological	ADJ
bptjm-29	3	8	approaches	approach	NOUN
bptjm-29	3	9	,	,	PUNCT
bptjm-29	3	10	are	be	AUX
bptjm-29	3	11	not	not	PART
bptjm-29	3	12	highly	highly	ADV
bptjm-29	3	13	targeted	target	VERB
bptjm-29	3	14	and	and	CCONJ
bptjm-29	3	15	only	only	ADV
bptjm-29	3	16	offer	offer	VERB
bptjm-29	3	17	short	short	ADV
bptjm-29	3	18	-	-	PUNCT
bptjm-29	3	19	lived	live	VERB
bptjm-29	3	20	benefits	benefit	NOUN
bptjm-29	3	21	.	.	PUNCT
bptjm-29	4	1	no	no	DET
bptjm-29	4	2	cure	cure	NOUN
bptjm-29	4	3	for	for	ADP
bptjm-29	4	4	the	the	DET
bptjm-29	4	5	disease	disease	NOUN
bptjm-29	4	6	exists	exist	VERB
bptjm-29	4	7	to	to	ADP
bptjm-29	4	8	date	date	NOUN
bptjm-29	4	9	.	.	PUNCT
bptjm-29	5	1	however	however	ADV
bptjm-29	5	2	,	,	PUNCT
bptjm-29	5	3	mesenchymal	mesenchymal	ADJ
bptjm-29	5	4	stem	stem	NOUN
bptjm-29	5	5	cells	cell	NOUN
bptjm-29	5	6	,	,	PUNCT
bptjm-29	5	7	which	which	PRON
bptjm-29	5	8	are	be	AUX
bptjm-29	5	9	adult	adult	NOUN
bptjm-29	5	10	stem	stem	NOUN
bptjm-29	5	11	cells	cell	NOUN
bptjm-29	5	12	that	that	PRON
bptjm-29	5	13	are	be	AUX
bptjm-29	5	14	highly	highly	ADV
bptjm-29	5	15	accessible	accessible	ADJ
bptjm-29	5	16	and	and	CCONJ
bptjm-29	5	17	can	can	AUX
bptjm-29	5	18	differentiate	differentiate	VERB
bptjm-29	5	19	into	into	ADP
bptjm-29	5	20	different	different	ADJ
bptjm-29	5	21	types	type	NOUN
bptjm-29	5	22	of	of	ADP
bptjm-29	5	23	tissue	tissue	NOUN
bptjm-29	5	24	,	,	PUNCT
bptjm-29	5	25	are	be	AUX
bptjm-29	5	26	currently	currently	ADV
bptjm-29	5	27	being	be	AUX
bptjm-29	5	28	studied	study	VERB
bptjm-29	5	29	.	.	PUNCT
bptjm-29	6	1	this	this	DET
bptjm-29	6	2	review	review	NOUN
bptjm-29	6	3	offers	offer	VERB
bptjm-29	6	4	insight	insight	NOUN
bptjm-29	6	5	into	into	ADP
bptjm-29	6	6	some	some	PRON
bptjm-29	6	7	of	of	ADP
bptjm-29	6	8	the	the	DET
bptjm-29	6	9	pathogenetic	pathogenetic	ADJ
bptjm-29	6	10	mechanisms	mechanism	NOUN
bptjm-29	6	11	,	,	PUNCT
bptjm-29	6	12	potential	potential	ADJ
bptjm-29	6	13	treatments	treatment	NOUN
bptjm-29	6	14	,	,	PUNCT
bptjm-29	6	15	and	and	CCONJ
bptjm-29	6	16	how	how	SCONJ
bptjm-29	6	17	mesenchymal	mesenchymal	ADJ
bptjm-29	6	18	stem	stem	NOUN
bptjm-29	6	19	cell	cell	NOUN
bptjm-29	6	20	treatment	treatment	NOUN
bptjm-29	6	21	could	could	AUX
bptjm-29	6	22	be	be	AUX
bptjm-29	6	23	the	the	DET
bptjm-29	6	24	potential	potential	ADJ
bptjm-29	6	25	cure	cure	NOUN
bptjm-29	6	26	for	for	ADP
bptjm-29	6	27	als	al	NOUN
bptjm-29	6	28	.	.	PUNCT
bptjm-29	7	1	administration	administration	NOUN
bptjm-29	7	2	of	of	ADP
bptjm-29	7	3	mesenchymal	mesenchymal	NOUN
bptjm-29	7	4	stem	stem	NOUN
bptjm-29	7	5	cells	cell	NOUN
bptjm-29	7	6	as	as	ADP
bptjm-29	7	7	a	a	DET
bptjm-29	7	8	therapeutic	therapeutic	NOUN
bptjm-29	7	9	for	for	ADP
bptjm-29	7	10	amyotrophic	amyotrophic	ADJ
bptjm-29	7	11	lateral	lateral	ADJ
bptjm-29	7	12	sclerosis	sclerosis	NOUN
bptjm-29	7	13	by	by	ADP
bptjm-29	7	14	:	:	PUNCT
bptjm-29	7	15	tanvi	tanvi	NOUN
bptjm-29	7	16	yalamanchili	yalamanchili	NOUN
bptjm-29	7	17	,	,	PUNCT
bptjm-29	7	18	saahil	saahil	NOUN
bptjm-29	7	19	mohta	mohta	NOUN
bptjm-29	7	20	and	and	CCONJ
bptjm-29	7	21	donna	donna	VERB
bptjm-29	7	22	tran	tran	PROPN
bptjm-29	7	23	1	1	PROPN
bptjm-29	7	24	.	.	PUNCT
bptjm-29	8	1	introduction	introduction	NOUN
bptjm-29	8	2	als	als	NOUN
bptjm-29	8	3	is	be	AUX
bptjm-29	8	4	a	a	DET
bptjm-29	8	5	progressive	progressive	ADJ
bptjm-29	8	6	neurodegenerative	neurodegenerative	ADJ
bptjm-29	8	7	disease	disease	NOUN
bptjm-29	8	8	caused	cause	VERB
bptjm-29	8	9	by	by	ADP
bptjm-29	8	10	the	the	DET
bptjm-29	8	11	loss	loss	NOUN
bptjm-29	8	12	of	of	ADP
bptjm-29	8	13	brain	brain	NOUN
bptjm-29	8	14	connectivity	connectivity	NOUN
bptjm-29	8	15	to	to	ADP
bptjm-29	8	16	the	the	DET
bptjm-29	8	17	muscles	muscle	NOUN
bptjm-29	8	18	.	.	PUNCT
bptjm-29	9	1	as	as	SCONJ
bptjm-29	9	2	motor	motor	NOUN
bptjm-29	9	3	neurons	neuron	NOUN
bptjm-29	9	4	degenerate	degenerate	VERB
bptjm-29	9	5	or	or	CCONJ
bptjm-29	9	6	die	die	VERB
bptjm-29	9	7	,	,	PUNCT
bptjm-29	9	8	the	the	DET
bptjm-29	9	9	muscles	muscle	NOUN
bptjm-29	9	10	weaken	weaken	VERB
bptjm-29	9	11	,	,	PUNCT
bptjm-29	9	12	eventually	eventually	ADV
bptjm-29	9	13	leading	lead	VERB
bptjm-29	9	14	to	to	ADP
bptjm-29	9	15	paralysis1	paralysis1	PROPN
bptjm-29	9	16	.	.	PUNCT
bptjm-29	10	1	motor	motor	NOUN
bptjm-29	10	2	neurons	neuron	NOUN
bptjm-29	10	3	are	be	AUX
bptjm-29	10	4	specialized	specialized	ADJ
bptjm-29	10	5	brain	brain	NOUN
bptjm-29	10	6	cells	cell	NOUN
bptjm-29	10	7	located	locate	VERB
bptjm-29	10	8	in	in	ADP
bptjm-29	10	9	the	the	DET
bptjm-29	10	10	brain	brain	NOUN
bptjm-29	10	11	and	and	CCONJ
bptjm-29	10	12	spinal	spinal	ADJ
bptjm-29	10	13	cord	cord	NOUN
bptjm-29	10	14	and	and	CCONJ
bptjm-29	10	15	control	control	VERB
bptjm-29	10	16	the	the	DET
bptjm-29	10	17	motor	motor	NOUN
bptjm-29	10	18	function	function	NOUN
bptjm-29	10	19	of	of	ADP
bptjm-29	10	20	the	the	DET
bptjm-29	10	21	body	body	NOUN
bptjm-29	10	22	.	.	PUNCT
bptjm-29	11	1	there	there	PRON
bptjm-29	11	2	are	be	VERB
bptjm-29	11	3	two	two	NUM
bptjm-29	11	4	types	type	NOUN
bptjm-29	11	5	of	of	ADP
bptjm-29	11	6	motor	motor	NOUN
bptjm-29	11	7	neurons	neuron	NOUN
bptjm-29	11	8	:	:	PUNCT
bptjm-29	11	9	upper	upper	ADJ
bptjm-29	11	10	motor	motor	NOUN
bptjm-29	11	11	neurons	neuron	NOUN
bptjm-29	11	12	,	,	PUNCT
bptjm-29	11	13	which	which	PRON
bptjm-29	11	14	originate	originate	VERB
bptjm-29	11	15	in	in	ADP
bptjm-29	11	16	the	the	DET
bptjm-29	11	17	brain	brain	NOUN
bptjm-29	11	18	,	,	PUNCT
bptjm-29	11	19	and	and	CCONJ
bptjm-29	11	20	lower	low	ADJ
bptjm-29	11	21	motor	motor	NOUN
bptjm-29	11	22	neurons	neuron	NOUN
bptjm-29	11	23	,	,	PUNCT
bptjm-29	11	24	which	which	PRON
bptjm-29	11	25	send	send	VERB
bptjm-29	11	26	signals	signal	NOUN
bptjm-29	11	27	from	from	ADP
bptjm-29	11	28	the	the	DET
bptjm-29	11	29	brain	brain	NOUN
bptjm-29	11	30	to	to	ADP
bptjm-29	11	31	the	the	DET
bptjm-29	11	32	spinal	spinal	ADJ
bptjm-29	11	33	cord	cord	NOUN
bptjm-29	11	34	and	and	CCONJ
bptjm-29	11	35	then	then	ADV
bptjm-29	11	36	to	to	ADP
bptjm-29	11	37	the	the	DET
bptjm-29	11	38	target	target	NOUN
bptjm-29	11	39	muscles2	muscles2	NOUN
bptjm-29	11	40	.	.	PUNCT
bptjm-29	12	1	the	the	DET
bptjm-29	12	2	disease	disease	NOUN
bptjm-29	12	3	leads	lead	VERB
bptjm-29	12	4	to	to	ADP
bptjm-29	12	5	the	the	DET
bptjm-29	12	6	degeneration	degeneration	NOUN
bptjm-29	12	7	of	of	ADP
bptjm-29	12	8	upper	upper	ADJ
bptjm-29	12	9	motor	motor	NOUN
bptjm-29	12	10	neurons	neuron	NOUN
bptjm-29	12	11	in	in	ADP
bptjm-29	12	12	the	the	DET
bptjm-29	12	13	primary	primary	ADJ
bptjm-29	12	14	cortex	cortex	NOUN
bptjm-29	12	15	and	and	CCONJ
bptjm-29	12	16	the	the	DET
bptjm-29	12	17	degeneration	degeneration	NOUN
bptjm-29	12	18	of	of	ADP
bptjm-29	12	19	lower	low	ADJ
bptjm-29	12	20	motor	motor	NOUN
bptjm-29	12	21	neurons	neuron	NOUN
bptjm-29	12	22	in	in	ADP
bptjm-29	12	23	the	the	DET
bptjm-29	12	24	brainstem	brainstem	NOUN
bptjm-29	12	25	and	and	CCONJ
bptjm-29	12	26	the	the	DET
bptjm-29	12	27	spinal	spinal	ADJ
bptjm-29	12	28	cord1	cord1	NOUN
bptjm-29	12	29	.	.	PUNCT
bptjm-29	13	1	the	the	DET
bptjm-29	13	2	word	word	NOUN
bptjm-29	13	3	“	"	PUNCT
bptjm-29	13	4	amyotrophic	amyotrophic	NOUN
bptjm-29	13	5	”	"	PUNCT
bptjm-29	13	6	comes	come	VERB
bptjm-29	13	7	from	from	ADP
bptjm-29	13	8	greek	greek	ADJ
bptjm-29	13	9	roots	root	NOUN
bptjm-29	13	10	that	that	PRON
bptjm-29	13	11	mean	mean	VERB
bptjm-29	13	12	“	"	PUNCT
bptjm-29	13	13	without	without	ADP
bptjm-29	13	14	nourishment	nourishment	NOUN
bptjm-29	13	15	to	to	ADP
bptjm-29	13	16	muscles	muscle	NOUN
bptjm-29	13	17	”	"	PUNCT
bptjm-29	13	18	and	and	CCONJ
bptjm-29	13	19	refers	refer	VERB
bptjm-29	13	20	to	to	ADP
bptjm-29	13	21	the	the	DET
bptjm-29	13	22	loss	loss	NOUN
bptjm-29	13	23	of	of	ADP
bptjm-29	13	24	signals	signal	NOUN
bptjm-29	13	25	nerve	nerve	NOUN
bptjm-29	13	26	cells	cell	NOUN
bptjm-29	13	27	normally	normally	ADV
bptjm-29	13	28	send	send	VERB
bptjm-29	13	29	to	to	ADP
bptjm-29	13	30	muscle	muscle	NOUN
bptjm-29	13	31	cells	cell	NOUN
bptjm-29	13	32	.	.	PUNCT
bptjm-29	14	1	therefore	therefore	ADV
bptjm-29	14	2	,	,	PUNCT
bptjm-29	14	3	an	an	DET
bptjm-29	14	4	important	important	ADJ
bptjm-29	14	5	e	e	NOUN
bptjm-29	14	6	�	�	NOUN
bptjm-29	14	7	ect	ect	ADP
bptjm-29	14	8	of	of	ADP
bptjm-29	14	9	als	als	NOUN
bptjm-29	14	10	is	be	AUX
bptjm-29	14	11	the	the	DET
bptjm-29	14	12	reduction	reduction	NOUN
bptjm-29	14	13	of	of	ADP
bptjm-29	14	14	the	the	DET
bptjm-29	14	15	blood	blood	NOUN
bptjm-29	14	16	-	-	PUNCT
bptjm-29	14	17	brain	brain	NOUN
bptjm-29	14	18	and	and	CCONJ
bptjm-29	14	19	blood	blood	NOUN
bptjm-29	14	20	-	-	PUNCT
bptjm-29	14	21	spinal	spinal	NOUN
bptjm-29	14	22	cord	cord	NOUN
bptjm-29	14	23	barriers	barrier	NOUN
bptjm-29	14	24	.	.	PUNCT
bptjm-29	15	1	these	these	DET
bptjm-29	15	2	barriers	barrier	NOUN
bptjm-29	15	3	are	be	AUX
bptjm-29	15	4	responsible	responsible	ADJ
bptjm-29	15	5	for	for	ADP
bptjm-29	15	6	brain	brain	NOUN
bptjm-29	15	7	homeostasis	homeostasis	NOUN
bptjm-29	15	8	,	,	PUNCT
bptjm-29	15	9	regulation	regulation	NOUN
bptjm-29	15	10	of	of	ADP
bptjm-29	15	11	in	in	ADP
bptjm-29	15	12	�	�	PROPN
bptjm-29	15	13	ux	ux	PROPN
bptjm-29	15	14	/	/	SYM
bptjm-29	15	15	e	e	PROPN
bptjm-29	15	16	�	�	PROPN
bptjm-29	15	17	ux	ux	ADJ
bptjm-29	15	18	transport	transport	NOUN
bptjm-29	15	19	,	,	PUNCT
bptjm-29	15	20	and	and	CCONJ
bptjm-29	15	21	protection	protection	NOUN
bptjm-29	15	22	from	from	ADP
bptjm-29	15	23	damage	damage	NOUN
bptjm-29	15	24	caused	cause	VERB
bptjm-29	15	25	by	by	ADP
bptjm-29	15	26	the	the	DET
bptjm-29	15	27	debris	debris	NOUN
bptjm-29	15	28	in	in	ADP
bptjm-29	15	29	the	the	DET
bptjm-29	15	30	bloodstream7	bloodstream7	PROPN
bptjm-29	15	31	.	.	PUNCT
bptjm-29	16	1	als	als	PROPN
bptjm-29	16	2	was	be	AUX
bptjm-29	16	3	�	�	PROPN
bptjm-29	16	4	rst	rst	PROPN
bptjm-29	16	5	discovered	discover	VERB
bptjm-29	16	6	in	in	ADP
bptjm-29	16	7	1869	1869	NUM
bptjm-29	16	8	by	by	ADP
bptjm-29	16	9	the	the	DET
bptjm-29	16	10	french	french	ADJ
bptjm-29	16	11	neurologist	neurologist	NOUN
bptjm-29	16	12	jean	jean	PROPN
bptjm-29	16	13	-	-	PUNCT
bptjm-29	16	14	martin	martin	PROPN
bptjm-29	16	15	charcot	charcot	PROPN
bptjm-29	16	16	but	but	CCONJ
bptjm-29	16	17	became	became	AUX
bptjm-29	16	18	more	more	ADV
bptjm-29	16	19	commonly	commonly	ADV
bptjm-29	16	20	known	know	VERB
bptjm-29	16	21	as	as	ADP
bptjm-29	16	22	lou	lou	PROPN
bptjm-29	16	23	gehrig	gehrig	PROPN
bptjm-29	16	24	’s	’s	PART
bptjm-29	16	25	disease	disease	NOUN
bptjm-29	16	26	after	after	SCONJ
bptjm-29	16	27	the	the	DET
bptjm-29	16	28	famous	famous	ADJ
bptjm-29	16	29	baseball	baseball	NOUN
bptjm-29	16	30	player	player	NOUN
bptjm-29	16	31	lou	lou	PROPN
bptjm-29	16	32	gehrig	gehrig	PROPN
bptjm-29	16	33	was	be	AUX
bptjm-29	16	34	diagnosed	diagnose	VERB
bptjm-29	16	35	with	with	ADP
bptjm-29	16	36	als	als	NOUN
bptjm-29	16	37	at	at	ADP
bptjm-29	16	38	the	the	DET
bptjm-29	16	39	age	age	NOUN
bptjm-29	16	40	of	of	ADP
bptjm-29	16	41	36	36	NUM
bptjm-29	16	42	.	.	PUNCT
bptjm-29	17	1	after	after	ADP
bptjm-29	17	2	being	be	AUX
bptjm-29	17	3	diagnosed	diagnose	VERB
bptjm-29	17	4	,	,	PUNCT
bptjm-29	17	5	the	the	DET
bptjm-29	17	6	yankee	yankee	PROPN
bptjm-29	17	7	player	player	NOUN
bptjm-29	17	8	retired	retire	VERB
bptjm-29	17	9	soon	soon	ADV
bptjm-29	17	10	after	after	ADV
bptjm-29	17	11	as	as	SCONJ
bptjm-29	17	12	he	he	PRON
bptjm-29	17	13	experienced	experience	VERB
bptjm-29	17	14	symptoms	symptom	NOUN
bptjm-29	17	15	such	such	ADJ
bptjm-29	17	16	as	as	ADP
bptjm-29	17	17	loss	loss	NOUN
bptjm-29	17	18	of	of	ADP
bptjm-29	17	19	strength	strength	NOUN
bptjm-29	17	20	,	,	PUNCT
bptjm-29	17	21	and	and	CCONJ
bptjm-29	17	22	loss	loss	NOUN
bptjm-29	17	23	of	of	ADP
bptjm-29	17	24	coordination	coordination	NOUN
bptjm-29	17	25	,	,	PUNCT
bptjm-29	17	26	making	make	VERB
bptjm-29	17	27	him	he	PRON
bptjm-29	17	28	un	un	PROPN
bptjm-29	17	29	�	�	PROPN
bptjm-29	17	30	t	t	PROPN
bptjm-29	17	31	on	on	ADP
bptjm-29	17	32	the	the	DET
bptjm-29	17	33	�	�	PROPN
bptjm-29	17	34	eld3	eld3	PROPN
bptjm-29	17	35	.	.	PUNCT
bptjm-29	18	1	as	as	ADP
bptjm-29	18	2	a	a	DET
bptjm-29	18	3	progressive	progressive	ADJ
bptjm-29	18	4	disease	disease	NOUN
bptjm-29	18	5	,	,	PUNCT
bptjm-29	18	6	als	als	VERB
bptjm-29	18	7	causes	cause	VERB
bptjm-29	18	8	motor	motor	NOUN
bptjm-29	18	9	neuron	neuron	PROPN
bptjm-29	18	10	degeneration	degeneration	NOUN
bptjm-29	18	11	to	to	PART
bptjm-29	18	12	worsen	worsen	VERB
bptjm-29	18	13	until	until	SCONJ
bptjm-29	18	14	the	the	DET
bptjm-29	18	15	patient	patient	NOUN
bptjm-29	18	16	passes	pass	VERB
bptjm-29	18	17	away1	away1	NOUN
bptjm-29	18	18	.	.	PUNCT
bptjm-29	19	1	symptoms	symptom	NOUN
bptjm-29	19	2	in	in	ADP
bptjm-29	19	3	the	the	DET
bptjm-29	19	4	early	early	ADJ
bptjm-29	19	5	stages	stage	NOUN
bptjm-29	19	6	of	of	ADP
bptjm-29	19	7	the	the	DET
bptjm-29	19	8	disease	disease	NOUN
bptjm-29	19	9	include	include	VERB
bptjm-29	19	10	fatigue	fatigue	NOUN
bptjm-29	19	11	,	,	PUNCT
bptjm-29	19	12	poor	poor	ADJ
bptjm-29	19	13	balance	balance	NOUN
bptjm-29	19	14	,	,	PUNCT
bptjm-29	19	15	slurred	slur	VERB
bptjm-29	19	16	speech	speech	NOUN
bptjm-29	19	17	,	,	PUNCT
bptjm-29	19	18	and	and	CCONJ
bptjm-29	19	19	tripping	trip	VERB
bptjm-29	19	20	due	due	ADJ
bptjm-29	19	21	to	to	ADP
bptjm-29	19	22	fasciculations	fasciculation	NOUN
bptjm-29	19	23	(	(	PUNCT
bptjm-29	19	24	spontaneous	spontaneous	ADJ
bptjm-29	19	25	muscle	muscle	NOUN
bptjm-29	19	26	contractions	contraction	NOUN
bptjm-29	19	27	/	/	SYM
bptjm-29	19	28	twitches	twitch	NOUN
bptjm-29	19	29	)	)	PUNCT
bptjm-29	19	30	and	and	CCONJ
bptjm-29	19	31	atrophy	atrophy	NOUN
bptjm-29	19	32	(	(	PUNCT
bptjm-29	19	33	loss	loss	NOUN
bptjm-29	19	34	of	of	ADP
bptjm-29	19	35	muscle	muscle	NOUN
bptjm-29	19	36	tissue)4	tissue)4	NUM
bptjm-29	19	37	.	.	PUNCT
bptjm-29	20	1	as	as	SCONJ
bptjm-29	20	2	some	some	DET
bptjm-29	20	3	muscles	muscle	NOUN
bptjm-29	20	4	paralyze	paralyze	VERB
bptjm-29	20	5	,	,	PUNCT
bptjm-29	20	6	fasciculations	fasciculation	NOUN
bptjm-29	20	7	continue	continue	VERB
bptjm-29	20	8	,	,	PUNCT
bptjm-29	20	9	and	and	CCONJ
bptjm-29	20	10	joints	joint	NOUN
bptjm-29	20	11	start	start	VERB
bptjm-29	20	12	to	to	PART
bptjm-29	20	13	become	become	VERB
bptjm-29	20	14	rigid	rigid	ADJ
bptjm-29	20	15	and	and	CCONJ
bptjm-29	20	16	painful	painful	ADJ
bptjm-29	20	17	.	.	PUNCT
bptjm-29	21	1	walking	walk	VERB
bptjm-29	21	2	,	,	PUNCT
bptjm-29	21	3	eating	eat	VERB
bptjm-29	21	4	and	and	CCONJ
bptjm-29	21	5	breathing	breathing	NOUN
bptjm-29	21	6	start	start	VERB
bptjm-29	21	7	to	to	PART
bptjm-29	21	8	become	become	VERB
bptjm-29	21	9	di	di	NOUN
bptjm-29	21	10	�	�	NOUN
bptjm-29	21	11	cult	cult	NOUN
bptjm-29	21	12	.	.	PUNCT
bptjm-29	22	1	some	some	DET
bptjm-29	22	2	people	people	NOUN
bptjm-29	22	3	have	have	AUX
bptjm-29	22	4	uncontrolled	uncontrolle	VERB
bptjm-29	22	5	crying	crying	NOUN
bptjm-29	22	6	or	or	CCONJ
bptjm-29	22	7	laughter	laughter	NOUN
bptjm-29	22	8	.	.	PUNCT
bptjm-29	23	1	in	in	ADP
bptjm-29	23	2	the	the	DET
bptjm-29	23	3	late	late	ADJ
bptjm-29	23	4	stages	stage	NOUN
bptjm-29	23	5	of	of	ADP
bptjm-29	23	6	the	the	DET
bptjm-29	23	7	disease	disease	NOUN
bptjm-29	23	8	,	,	PUNCT
bptjm-29	23	9	the	the	DET
bptjm-29	23	10	patients	patient	NOUN
bptjm-29	23	11	’	'	PUNCT
bptjm-29	23	12	voluntary	voluntary	ADJ
bptjm-29	23	13	muscles	muscle	NOUN
bptjm-29	23	14	become	become	VERB
bptjm-29	23	15	paralyzed	paralyzed	ADJ
bptjm-29	23	16	,	,	PUNCT
bptjm-29	23	17	and	and	CCONJ
bptjm-29	23	18	the	the	DET
bptjm-29	23	19	muscles	muscle	NOUN
bptjm-29	23	20	that	that	PRON
bptjm-29	23	21	help	help	VERB
bptjm-29	23	22	expand	expand	VERB
bptjm-29	23	23	and	and	CCONJ
bptjm-29	23	24	contract	contract	VERB
bptjm-29	23	25	the	the	DET
bptjm-29	23	26	lungs	lung	NOUN
bptjm-29	23	27	for	for	ADP
bptjm-29	23	28	air	air	NOUN
bptjm-29	23	29	are	be	AUX
bptjm-29	23	30	compromised	compromise	VERB
bptjm-29	23	31	,	,	PUNCT
bptjm-29	23	32	leading	lead	VERB
bptjm-29	23	33	to	to	ADP
bptjm-29	23	34	respiratory	respiratory	ADJ
bptjm-29	23	35	failure5,6	failure5,6	PROPN
bptjm-29	23	36	.	.	PUNCT
bptjm-29	24	1	berkeley	berkeley	PROPN
bptjm-29	24	2	pharma	pharma	PROPN
bptjm-29	24	3	tech	tech	PROPN
bptjm-29	24	4	journal	journal	NOUN
bptjm-29	24	5	of	of	ADP
bptjm-29	24	6	medicine	medicine	NOUN
bptjm-29	24	7	|	|	ADV
bptjm-29	24	8	71	71	NUM
bptjm-29	24	9	https://www.zotero.org/google-docs/?41igcv	https://www.zotero.org/google-docs/?41igcv	PROPN
bptjm-29	24	10	https://www.zotero.org/google-docs/?xobdid	https://www.zotero.org/google-docs/?xobdid	PROPN
bptjm-29	24	11	https://www.zotero.org/google-docs/?rk7qzn	https://www.zotero.org/google-docs/?rk7qzn	PROPN
bptjm-29	24	12	https://www.zotero.org/google-docs/?otzlqz	https://www.zotero.org/google-docs/?otzlqz	PROPN
bptjm-29	24	13	https://www.zotero.org/google-docs/?mhiodq	https://www.zotero.org/google-docs/?mhiodq	PROPN
bptjm-29	24	14	https://www.zotero.org/google-docs/?xylydq	https://www.zotero.org/google-docs/?xylydq	NOUN
bptjm-29	24	15	https://www.zotero.org/google-docs/?ur2rcy	https://www.zotero.org/google-docs/?ur2rcy	PUNCT
bptjm-29	25	1	https://www.zotero.org/google-docs/?wna0u2	https://www.zotero.org/google-docs/?wna0u2	PROPN
bptjm-29	25	2	https://www.zotero.org/google-docs/?o2bl6i	https://www.zotero.org/google-docs/?o2bl6i	PUNCT
bptjm-29	25	3	around	around	ADV
bptjm-29	25	4	5000	5000	NUM
bptjm-29	25	5	people	people	NOUN
bptjm-29	25	6	are	be	AUX
bptjm-29	25	7	diagnosed	diagnose	VERB
bptjm-29	25	8	with	with	ADP
bptjm-29	25	9	als	als	NOUN
bptjm-29	25	10	every	every	DET
bptjm-29	25	11	year	year	NOUN
bptjm-29	25	12	,	,	PUNCT
bptjm-29	25	13	and	and	CCONJ
bptjm-29	25	14	someone	someone	PRON
bptjm-29	25	15	dies	die	VERB
bptjm-29	25	16	from	from	ADP
bptjm-29	25	17	the	the	DET
bptjm-29	25	18	disease	disease	NOUN
bptjm-29	25	19	every	every	DET
bptjm-29	25	20	90	90	NUM
bptjm-29	25	21	minutes	minute	NOUN
bptjm-29	25	22	.	.	PUNCT
bptjm-29	26	1	once	once	ADV
bptjm-29	26	2	diagnosed	diagnose	VERB
bptjm-29	26	3	,	,	PUNCT
bptjm-29	26	4	the	the	DET
bptjm-29	26	5	average	average	ADJ
bptjm-29	26	6	life	life	NOUN
bptjm-29	26	7	expectancy	expectancy	NOUN
bptjm-29	26	8	is	be	AUX
bptjm-29	26	9	two	two	NUM
bptjm-29	26	10	to	to	PART
bptjm-29	26	11	�	�	PROPN
bptjm-29	26	12	ve	ve	NOUN
bptjm-29	26	13	years	year	NOUN
bptjm-29	26	14	.	.	PUNCT
bptjm-29	27	1	although	although	SCONJ
bptjm-29	27	2	it	it	PRON
bptjm-29	27	3	is	be	AUX
bptjm-29	27	4	most	most	ADV
bptjm-29	27	5	common	common	ADJ
bptjm-29	27	6	for	for	SCONJ
bptjm-29	27	7	the	the	DET
bptjm-29	27	8	disease	disease	NOUN
bptjm-29	27	9	to	to	PART
bptjm-29	27	10	develop	develop	VERB
bptjm-29	27	11	at	at	ADP
bptjm-29	27	12	ages	age	NOUN
bptjm-29	27	13	greater	great	ADJ
bptjm-29	27	14	than	than	ADP
bptjm-29	27	15	60	60	NUM
bptjm-29	27	16	years	year	NOUN
bptjm-29	27	17	,	,	PUNCT
bptjm-29	27	18	it	it	PRON
bptjm-29	27	19	can	can	AUX
bptjm-29	27	20	occur	occur	VERB
bptjm-29	27	21	at	at	ADP
bptjm-29	27	22	younger	young	ADJ
bptjm-29	27	23	ages	age	NOUN
bptjm-29	27	24	as	as	ADP
bptjm-29	27	25	well6	well6	NOUN
bptjm-29	27	26	.	.	PUNCT
bptjm-29	28	1	there	there	PRON
bptjm-29	28	2	are	be	VERB
bptjm-29	28	3	two	two	NUM
bptjm-29	28	4	types	type	NOUN
bptjm-29	28	5	of	of	ADP
bptjm-29	28	6	als	als	NOUN
bptjm-29	28	7	cases	case	NOUN
bptjm-29	28	8	:	:	PUNCT
bptjm-29	28	9	familial	familial	ADJ
bptjm-29	28	10	als	als	NOUN
bptjm-29	28	11	(	(	PUNCT
bptjm-29	28	12	fals	fal	NOUN
bptjm-29	28	13	)	)	PUNCT
bptjm-29	28	14	and	and	CCONJ
bptjm-29	28	15	sporadic	sporadic	ADJ
bptjm-29	28	16	als	als	NOUN
bptjm-29	28	17	(	(	PUNCT
bptjm-29	28	18	sals)7	sals)7	X
bptjm-29	28	19	.	.	PUNCT
bptjm-29	29	1	familial	familial	ADJ
bptjm-29	29	2	als	als	NOUN
bptjm-29	29	3	occurs	occur	VERB
bptjm-29	29	4	due	due	ADJ
bptjm-29	29	5	to	to	ADP
bptjm-29	29	6	genetic	genetic	ADJ
bptjm-29	29	7	inheritance	inheritance	NOUN
bptjm-29	29	8	,	,	PUNCT
bptjm-29	29	9	and	and	CCONJ
bptjm-29	29	10	accounts	account	VERB
bptjm-29	29	11	for	for	ADP
bptjm-29	29	12	only	only	ADV
bptjm-29	29	13	5	5	NUM
bptjm-29	29	14	-	-	SYM
bptjm-29	29	15	10	10	NUM
bptjm-29	29	16	%	%	NOUN
bptjm-29	29	17	of	of	ADP
bptjm-29	29	18	als	als	NOUN
bptjm-29	29	19	cases	case	NOUN
bptjm-29	29	20	.	.	PUNCT
bptjm-29	30	1	it	it	PRON
bptjm-29	30	2	has	have	VERB
bptjm-29	30	3	an	an	DET
bptjm-29	30	4	earlier	early	ADJ
bptjm-29	30	5	age	age	NOUN
bptjm-29	30	6	of	of	ADP
bptjm-29	30	7	onset	onset	NOUN
bptjm-29	30	8	compared	compare	VERB
bptjm-29	30	9	to	to	ADP
bptjm-29	30	10	sals6,7	sals6,7	PROPN
bptjm-29	30	11	.	.	PUNCT
bptjm-29	31	1	it	it	PRON
bptjm-29	31	2	is	be	AUX
bptjm-29	31	3	known	know	VERB
bptjm-29	31	4	to	to	PART
bptjm-29	31	5	primarily	primarily	ADV
bptjm-29	31	6	take	take	VERB
bptjm-29	31	7	form	form	NOUN
bptjm-29	31	8	as	as	ADP
bptjm-29	31	9	a	a	DET
bptjm-29	31	10	result	result	NOUN
bptjm-29	31	11	of	of	ADP
bptjm-29	31	12	gene	gene	NOUN
bptjm-29	31	13	mutations	mutation	NOUN
bptjm-29	31	14	such	such	ADJ
bptjm-29	31	15	as	as	ADP
bptjm-29	31	16	sod1	sod1	ADJ
bptjm-29	31	17	mutations	mutation	NOUN
bptjm-29	31	18	.	.	PUNCT
bptjm-29	32	1	over	over	ADP
bptjm-29	32	2	20	20	NUM
bptjm-29	32	3	gene	gene	NOUN
bptjm-29	32	4	mutations	mutation	NOUN
bptjm-29	32	5	have	have	AUX
bptjm-29	32	6	now	now	ADV
bptjm-29	32	7	been	be	AUX
bptjm-29	32	8	identi	identi	X
bptjm-29	32	9	�	�	PROPN
bptjm-29	32	10	ed	ed	NOUN
bptjm-29	32	11	that	that	PRON
bptjm-29	32	12	play	play	VERB
bptjm-29	32	13	a	a	DET
bptjm-29	32	14	role	role	NOUN
bptjm-29	32	15	in	in	ADP
bptjm-29	32	16	als	als	NOUN
bptjm-29	32	17	disease	disease	NOUN
bptjm-29	32	18	progression	progression	NOUN
bptjm-29	32	19	.	.	PUNCT
bptjm-29	33	1	silence	silence	NOUN
bptjm-29	33	2	superoxide	superoxide	NOUN
bptjm-29	33	3	dismutase	dismutase	NOUN
bptjm-29	33	4	1	1	NUM
bptjm-29	33	5	(	(	PUNCT
bptjm-29	33	6	sod1	sod1	NOUN
bptjm-29	33	7	)	)	PUNCT
bptjm-29	33	8	is	be	AUX
bptjm-29	33	9	a	a	DET
bptjm-29	33	10	major	major	ADJ
bptjm-29	33	11	gene	gene	NOUN
bptjm-29	33	12	correlated	correlate	VERB
bptjm-29	33	13	with	with	ADP
bptjm-29	33	14	als	al	NOUN
bptjm-29	33	15	.	.	PUNCT
bptjm-29	34	1	sporadic	sporadic	ADJ
bptjm-29	34	2	als	als	NOUN
bptjm-29	34	3	on	on	ADP
bptjm-29	34	4	the	the	DET
bptjm-29	34	5	other	other	ADJ
bptjm-29	34	6	hand	hand	NOUN
bptjm-29	34	7	,	,	PUNCT
bptjm-29	34	8	although	although	SCONJ
bptjm-29	34	9	phenotypically	phenotypically	ADV
bptjm-29	34	10	indistinguishable	indistinguishable	ADJ
bptjm-29	34	11	from	from	ADP
bptjm-29	34	12	fals	fal	NOUN
bptjm-29	34	13	,	,	PUNCT
bptjm-29	34	14	is	be	AUX
bptjm-29	34	15	not	not	PART
bptjm-29	34	16	genetically	genetically	ADV
bptjm-29	34	17	inherited	inherit	VERB
bptjm-29	34	18	.	.	PUNCT
bptjm-29	35	1	as	as	ADP
bptjm-29	35	2	the	the	DET
bptjm-29	35	3	most	most	ADV
bptjm-29	35	4	common	common	ADJ
bptjm-29	35	5	form	form	NOUN
bptjm-29	35	6	of	of	ADP
bptjm-29	35	7	als	al	NOUN
bptjm-29	35	8	,	,	PUNCT
bptjm-29	35	9	sals	sal	NOUN
bptjm-29	35	10	accounts	account	VERB
bptjm-29	35	11	for	for	ADP
bptjm-29	35	12	90	90	NUM
bptjm-29	35	13	-	-	SYM
bptjm-29	35	14	95	95	NUM
bptjm-29	35	15	%	%	NOUN
bptjm-29	35	16	of	of	ADP
bptjm-29	35	17	all	all	DET
bptjm-29	35	18	cases6,7	cases6,7	PROPN
bptjm-29	35	19	.	.	PUNCT
bptjm-29	36	1	although	although	SCONJ
bptjm-29	36	2	the	the	DET
bptjm-29	36	3	cause	cause	NOUN
bptjm-29	36	4	for	for	ADP
bptjm-29	36	5	als	als	NOUN
bptjm-29	36	6	is	be	AUX
bptjm-29	36	7	unknown	unknown	ADJ
bptjm-29	36	8	,	,	PUNCT
bptjm-29	36	9	the	the	DET
bptjm-29	36	10	growing	grow	VERB
bptjm-29	36	11	evidence	evidence	NOUN
bptjm-29	36	12	points	point	VERB
bptjm-29	36	13	to	to	ADP
bptjm-29	36	14	the	the	DET
bptjm-29	36	15	possibility	possibility	NOUN
bptjm-29	36	16	of	of	ADP
bptjm-29	36	17	disease	disease	NOUN
bptjm-29	36	18	occurrence	occurrence	NOUN
bptjm-29	36	19	in	in	ADP
bptjm-29	36	20	humans	human	NOUN
bptjm-29	36	21	due	due	ADP
bptjm-29	36	22	to	to	ADP
bptjm-29	36	23	gene	gene	NOUN
bptjm-29	36	24	-	-	PUNCT
bptjm-29	36	25	environment	environment	NOUN
bptjm-29	36	26	interactions	interaction	NOUN
bptjm-29	36	27	.	.	PUNCT
bptjm-29	37	1	exposure	exposure	NOUN
bptjm-29	37	2	to	to	ADP
bptjm-29	37	3	certain	certain	ADJ
bptjm-29	37	4	toxic	toxic	ADJ
bptjm-29	37	5	substances	substance	NOUN
bptjm-29	37	6	,	,	PUNCT
bptjm-29	37	7	viruses	virus	NOUN
bptjm-29	37	8	,	,	PUNCT
bptjm-29	37	9	or	or	CCONJ
bptjm-29	37	10	physical	physical	ADJ
bptjm-29	37	11	trauma	trauma	NOUN
bptjm-29	37	12	could	could	AUX
bptjm-29	37	13	cause	cause	VERB
bptjm-29	37	14	the	the	DET
bptjm-29	37	15	disease6	disease6	NOUN
bptjm-29	37	16	.	.	PUNCT
bptjm-29	38	1	certain	certain	ADJ
bptjm-29	38	2	genes	gene	NOUN
bptjm-29	38	3	,	,	PUNCT
bptjm-29	38	4	known	know	VERB
bptjm-29	38	5	as	as	ADP
bptjm-29	38	6	“	"	PUNCT
bptjm-29	38	7	susceptibility	susceptibility	NOUN
bptjm-29	38	8	genes	gene	NOUN
bptjm-29	38	9	,	,	PUNCT
bptjm-29	38	10	”	"	PUNCT
bptjm-29	38	11	can	can	AUX
bptjm-29	38	12	trigger	trigger	VERB
bptjm-29	38	13	a	a	DET
bptjm-29	38	14	neurodegeneration	neurodegeneration	NOUN
bptjm-29	38	15	cascade	cascade	NOUN
bptjm-29	38	16	upon	upon	SCONJ
bptjm-29	38	17	interaction	interaction	NOUN
bptjm-29	38	18	with	with	ADP
bptjm-29	38	19	certain	certain	ADJ
bptjm-29	38	20	environmental	environmental	ADJ
bptjm-29	38	21	stimuli	stimulus	NOUN
bptjm-29	38	22	and/or	and/or	CCONJ
bptjm-29	38	23	factors	factor	NOUN
bptjm-29	38	24	.	.	PUNCT
bptjm-29	39	1	unfortunately	unfortunately	ADV
bptjm-29	39	2	,	,	PUNCT
bptjm-29	39	3	no	no	DET
bptjm-29	39	4	de	de	X
bptjm-29	39	5	�	�	NOUN
bptjm-29	39	6	nitive	nitive	ADJ
bptjm-29	39	7	environmental	environmental	ADJ
bptjm-29	39	8	risk	risk	NOUN
bptjm-29	39	9	factors	factor	NOUN
bptjm-29	39	10	have	have	AUX
bptjm-29	39	11	been	be	AUX
bptjm-29	39	12	identi	identi	ADJ
bptjm-29	39	13	�	�	PROPN
bptjm-29	39	14	ed	ed	NOUN
bptjm-29	39	15	for	for	ADP
bptjm-29	39	16	als	al	NOUN
bptjm-29	39	17	that	that	PRON
bptjm-29	39	18	can	can	AUX
bptjm-29	39	19	be	be	AUX
bptjm-29	39	20	replicated8	replicated8	ADJ
bptjm-29	39	21	.	.	PUNCT
bptjm-29	40	1	however	however	ADV
bptjm-29	40	2	,	,	PUNCT
bptjm-29	40	3	possible	possible	ADJ
bptjm-29	40	4	associations	association	NOUN
bptjm-29	40	5	,	,	PUNCT
bptjm-29	40	6	based	base	VERB
bptjm-29	40	7	on	on	ADP
bptjm-29	40	8	clinical	clinical	ADJ
bptjm-29	40	9	studies	study	NOUN
bptjm-29	40	10	,	,	PUNCT
bptjm-29	40	11	have	have	AUX
bptjm-29	40	12	been	be	AUX
bptjm-29	40	13	identi	identi	X
bptjm-29	40	14	�	�	NOUN
bptjm-29	40	15	ed	ed	NOUN
bptjm-29	40	16	between	between	ADP
bptjm-29	40	17	autoimmune	autoimmune	ADJ
bptjm-29	40	18	pathology	pathology	PROPN
bptjm-29	40	19	,	,	PUNCT
bptjm-29	40	20	neuroin	neuroin	PROPN
bptjm-29	40	21	�	�	PROPN
bptjm-29	40	22	ammation	ammation	NOUN
bptjm-29	40	23	,	,	PUNCT
bptjm-29	40	24	head	head	NOUN
bptjm-29	40	25	injury	injury	NOUN
bptjm-29	40	26	/	/	SYM
bptjm-29	40	27	trauma	trauma	NOUN
bptjm-29	40	28	,	,	PUNCT
bptjm-29	40	29	metabolic	metabolic	NOUN
bptjm-29	40	30	disease	disease	NOUN
bptjm-29	40	31	,	,	PUNCT
bptjm-29	40	32	and	and	CCONJ
bptjm-29	40	33	als	al	NOUN
bptjm-29	40	34	—	—	PUNCT
bptjm-29	40	35	speci	speci	ADJ
bptjm-29	40	36	�	�	NOUN
bptjm-29	40	37	cally	cally	ADV
bptjm-29	40	38	,	,	PUNCT
bptjm-29	40	39	the	the	DET
bptjm-29	40	40	pathogenesis	pathogenesis	NOUN
bptjm-29	40	41	of	of	ADP
bptjm-29	40	42	als8	als8	PROPN
bptjm-29	40	43	.	.	PUNCT
bptjm-29	41	1	there	there	PRON
bptjm-29	41	2	are	be	VERB
bptjm-29	41	3	four	four	NUM
bptjm-29	41	4	main	main	ADJ
bptjm-29	41	5	pathogenetic	pathogenetic	ADJ
bptjm-29	41	6	mechanisms	mechanism	NOUN
bptjm-29	41	7	that	that	PRON
bptjm-29	41	8	may	may	AUX
bptjm-29	41	9	explain	explain	VERB
bptjm-29	41	10	the	the	DET
bptjm-29	41	11	degeneration	degeneration	NOUN
bptjm-29	41	12	of	of	ADP
bptjm-29	41	13	motor	motor	NOUN
bptjm-29	41	14	neurons	neuron	NOUN
bptjm-29	41	15	;	;	PUNCT
bptjm-29	41	16	these	these	PRON
bptjm-29	41	17	include	include	VERB
bptjm-29	41	18	mitochondrial	mitochondrial	ADJ
bptjm-29	41	19	dysfunction	dysfunction	NOUN
bptjm-29	41	20	,	,	PUNCT
bptjm-29	41	21	glutamate	glutamate	VERB
bptjm-29	41	22	excitotoxicity	excitotoxicity	NOUN
bptjm-29	41	23	,	,	PUNCT
bptjm-29	41	24	oxidative	oxidative	ADJ
bptjm-29	41	25	stress	stress	NOUN
bptjm-29	41	26	,	,	PUNCT
bptjm-29	41	27	and	and	CCONJ
bptjm-29	41	28	in	in	ADP
bptjm-29	41	29	�	�	PROPN
bptjm-29	41	30	ammation	ammation	NOUN
bptjm-29	41	31	.	.	PUNCT
bptjm-29	42	1	current	current	ADJ
bptjm-29	42	2	treatments	treatment	NOUN
bptjm-29	42	3	include	include	VERB
bptjm-29	42	4	fda	fda	PROPN
bptjm-29	42	5	-	-	PUNCT
bptjm-29	42	6	approved	approve	VERB
bptjm-29	42	7	drugs	drug	NOUN
bptjm-29	42	8	such	such	ADJ
bptjm-29	42	9	as	as	ADP
bptjm-29	42	10	riluzole	riluzole	NOUN
bptjm-29	42	11	and	and	CCONJ
bptjm-29	42	12	edaravone9	edaravone9	PROPN
bptjm-29	42	13	.	.	PUNCT
bptjm-29	43	1	in	in	ADP
bptjm-29	43	2	addition	addition	NOUN
bptjm-29	43	3	,	,	PUNCT
bptjm-29	43	4	many	many	ADJ
bptjm-29	43	5	treatments	treatment	NOUN
bptjm-29	43	6	are	be	AUX
bptjm-29	43	7	being	be	AUX
bptjm-29	43	8	tested	test	VERB
bptjm-29	43	9	to	to	PART
bptjm-29	43	10	reduce	reduce	VERB
bptjm-29	43	11	the	the	DET
bptjm-29	43	12	e	e	NOUN
bptjm-29	43	13	�	�	NOUN
bptjm-29	43	14	ect	ect	NOUN
bptjm-29	43	15	of	of	ADP
bptjm-29	43	16	these	these	DET
bptjm-29	43	17	mechanisms	mechanism	NOUN
bptjm-29	43	18	,	,	PUNCT
bptjm-29	43	19	including	include	VERB
bptjm-29	43	20	but	but	CCONJ
bptjm-29	43	21	not	not	PART
bptjm-29	43	22	limited	limit	VERB
bptjm-29	43	23	to	to	ADP
bptjm-29	43	24	,	,	PUNCT
bptjm-29	43	25	sod1	sod1	ADJ
bptjm-29	43	26	gene	gene	NOUN
bptjm-29	43	27	therapy	therapy	NOUN
bptjm-29	43	28	,	,	PUNCT
bptjm-29	43	29	and	and	CCONJ
bptjm-29	43	30	astrocyte	astrocyte	PROPN
bptjm-29	43	31	transplantation9	transplantation9	PROPN
bptjm-29	43	32	.	.	PUNCT
bptjm-29	44	1	however	however	ADV
bptjm-29	44	2	,	,	PUNCT
bptjm-29	44	3	the	the	DET
bptjm-29	44	4	treatments	treatment	NOUN
bptjm-29	44	5	mentioned	mention	VERB
bptjm-29	44	6	above	above	ADV
bptjm-29	44	7	are	be	AUX
bptjm-29	44	8	berkeley	berkeley	PROPN
bptjm-29	44	9	pharma	pharma	PROPN
bptjm-29	44	10	tech	tech	NOUN
bptjm-29	44	11	journal	journal	NOUN
bptjm-29	44	12	of	of	ADP
bptjm-29	44	13	medicine	medicine	NOUN
bptjm-29	44	14	|	|	ADV
bptjm-29	44	15	72	72	NUM
bptjm-29	44	16	https://www.zotero.org/google-docs/?wa8ikg	https://www.zotero.org/google-docs/?wa8ikg	PUNCT
bptjm-29	44	17	https://www.zotero.org/google-docs/?broken=48p26	https://www.zotero.org/google-docs/?broken=48p26	NOUN
bptjm-29	44	18	t	t	PROPN
bptjm-29	44	19	https://www.zotero.org/google-docs/?broken=h5vp4v	https://www.zotero.org/google-docs/?broken=h5vp4v	NOUN
bptjm-29	44	20	either	either	CCONJ
bptjm-29	44	21	short	short	ADV
bptjm-29	44	22	-	-	PUNCT
bptjm-29	44	23	lived	live	VERB
bptjm-29	44	24	or	or	CCONJ
bptjm-29	44	25	only	only	ADV
bptjm-29	44	26	target	target	VERB
bptjm-29	44	27	one	one	NUM
bptjm-29	44	28	of	of	ADP
bptjm-29	44	29	the	the	DET
bptjm-29	44	30	pathogenetic	pathogenetic	ADJ
bptjm-29	44	31	mechanisms	mechanism	NOUN
bptjm-29	44	32	.	.	PUNCT
bptjm-29	45	1	of	of	ADP
bptjm-29	45	2	the	the	DET
bptjm-29	45	3	treatments	treatment	NOUN
bptjm-29	45	4	being	be	AUX
bptjm-29	45	5	studied	study	VERB
bptjm-29	45	6	,	,	PUNCT
bptjm-29	45	7	mesenchymal	mesenchymal	ADJ
bptjm-29	45	8	stem	stem	NOUN
bptjm-29	45	9	cells	cell	NOUN
bptjm-29	45	10	(	(	PUNCT
bptjm-29	45	11	mscs	msc	NOUN
bptjm-29	45	12	)	)	PUNCT
bptjm-29	45	13	stand	stand	VERB
bptjm-29	45	14	out	out	ADP
bptjm-29	45	15	as	as	ADP
bptjm-29	45	16	a	a	DET
bptjm-29	45	17	potential	potential	ADJ
bptjm-29	45	18	cure	cure	NOUN
bptjm-29	45	19	for	for	ADP
bptjm-29	45	20	als	al	NOUN
bptjm-29	45	21	.	.	PUNCT
bptjm-29	46	1	mscs	msc	NOUN
bptjm-29	46	2	not	not	PART
bptjm-29	46	3	only	only	ADV
bptjm-29	46	4	target	target	VERB
bptjm-29	46	5	the	the	DET
bptjm-29	46	6	pathogenetic	pathogenetic	ADJ
bptjm-29	46	7	mechanisms	mechanism	NOUN
bptjm-29	46	8	to	to	PART
bptjm-29	46	9	replace	replace	VERB
bptjm-29	46	10	dead	dead	ADJ
bptjm-29	46	11	cells	cell	NOUN
bptjm-29	46	12	with	with	ADP
bptjm-29	46	13	healthy	healthy	ADJ
bptjm-29	46	14	,	,	PUNCT
bptjm-29	46	15	di	di	NOUN
bptjm-29	46	16	�	�	PROPN
bptjm-29	46	17	erentiated	erentiate	VERB
bptjm-29	46	18	cells	cell	NOUN
bptjm-29	46	19	but	but	CCONJ
bptjm-29	46	20	they	they	PRON
bptjm-29	46	21	also	also	ADV
bptjm-29	46	22	repair	repair	VERB
bptjm-29	46	23	damaged	damage	VERB
bptjm-29	46	24	cells10	cells10	NOUN
bptjm-29	46	25	.	.	PUNCT
bptjm-29	47	1	stem	stem	NOUN
bptjm-29	47	2	cells	cell	NOUN
bptjm-29	47	3	are	be	AUX
bptjm-29	47	4	unique	unique	ADJ
bptjm-29	47	5	in	in	ADP
bptjm-29	47	6	their	their	PRON
bptjm-29	47	7	ability	ability	NOUN
bptjm-29	47	8	to	to	PART
bptjm-29	47	9	migrate	migrate	VERB
bptjm-29	47	10	to	to	ADP
bptjm-29	47	11	damaged	damage	VERB
bptjm-29	47	12	tissues	tissue	NOUN
bptjm-29	47	13	and/or	and/or	CCONJ
bptjm-29	47	14	sites	site	NOUN
bptjm-29	47	15	,	,	PUNCT
bptjm-29	47	16	stimulate	stimulate	VERB
bptjm-29	47	17	tissue	tissue	NOUN
bptjm-29	47	18	repair	repair	NOUN
bptjm-29	47	19	and	and	CCONJ
bptjm-29	47	20	regeneration	regeneration	NOUN
bptjm-29	47	21	,	,	PUNCT
bptjm-29	47	22	and	and	CCONJ
bptjm-29	47	23	di	di	NOUN
bptjm-29	47	24	�	�	PROPN
bptjm-29	47	25	erentiate	erentiate	NOUN
bptjm-29	47	26	in	in	ADP
bptjm-29	47	27	response	response	NOUN
bptjm-29	47	28	to	to	ADP
bptjm-29	47	29	extracellular	extracellular	ADJ
bptjm-29	47	30	signals	signal	NOUN
bptjm-29	47	31	.	.	PUNCT
bptjm-29	48	1	mscs	msc	NOUN
bptjm-29	48	2	are	be	AUX
bptjm-29	48	3	adult	adult	NOUN
bptjm-29	48	4	stem	stem	NOUN
bptjm-29	48	5	cells	cell	NOUN
bptjm-29	48	6	that	that	PRON
bptjm-29	48	7	contain	contain	VERB
bptjm-29	48	8	properties	property	NOUN
bptjm-29	48	9	of	of	ADP
bptjm-29	48	10	self	self	NOUN
bptjm-29	48	11	-	-	PUNCT
bptjm-29	48	12	renewal	renewal	NOUN
bptjm-29	48	13	,	,	PUNCT
bptjm-29	48	14	immunosuppressive	immunosuppressive	ADJ
bptjm-29	48	15	potential	potential	NOUN
bptjm-29	48	16	,	,	PUNCT
bptjm-29	48	17	and	and	CCONJ
bptjm-29	48	18	potency	potency	NOUN
bptjm-29	48	19	for	for	ADP
bptjm-29	48	20	trans	trans	PROPN
bptjm-29	48	21	-	-	PROPN
bptjm-29	48	22	di	di	NOUN
bptjm-29	48	23	�	�	PROPN
bptjm-29	48	24	erentiation	erentiation	NOUN
bptjm-29	48	25	into	into	ADP
bptjm-29	48	26	motor	motor	PROPN
bptjm-29	48	27	neurons10	neurons10	NOUN
bptjm-29	48	28	.	.	PUNCT
bptjm-29	49	1	in	in	ADP
bptjm-29	49	2	particular	particular	ADJ
bptjm-29	49	3	,	,	PUNCT
bptjm-29	49	4	mscs	msc	NOUN
bptjm-29	49	5	have	have	AUX
bptjm-29	49	6	been	be	AUX
bptjm-29	49	7	shown	show	VERB
bptjm-29	49	8	to	to	PART
bptjm-29	49	9	be	be	AUX
bptjm-29	49	10	a	a	DET
bptjm-29	49	11	promising	promising	ADJ
bptjm-29	49	12	therapeutic	therapeutic	NOUN
bptjm-29	49	13	for	for	ADP
bptjm-29	49	14	als	als	NOUN
bptjm-29	49	15	in	in	ADP
bptjm-29	49	16	preclinical	preclinical	ADJ
bptjm-29	49	17	and	and	CCONJ
bptjm-29	49	18	clinical	clinical	ADJ
bptjm-29	49	19	trials	trial	NOUN
bptjm-29	49	20	.	.	PUNCT
bptjm-29	50	1	mscs	msc	NOUN
bptjm-29	50	2	have	have	VERB
bptjm-29	50	3	the	the	DET
bptjm-29	50	4	ability	ability	NOUN
bptjm-29	50	5	to	to	PART
bptjm-29	50	6	stimulate	stimulate	VERB
bptjm-29	50	7	tissue	tissue	NOUN
bptjm-29	50	8	repair	repair	NOUN
bptjm-29	50	9	by	by	ADP
bptjm-29	50	10	di	di	PROPN
bptjm-29	50	11	�	�	PROPN
bptjm-29	50	12	erentiating	erentiate	VERB
bptjm-29	50	13	into	into	ADP
bptjm-29	50	14	motor	motor	PROPN
bptjm-29	50	15	neuron	neuron	PROPN
bptjm-29	50	16	cells	cell	NOUN
bptjm-29	50	17	,	,	PUNCT
bptjm-29	50	18	repair	repair	VERB
bptjm-29	50	19	damaged	damage	VERB
bptjm-29	50	20	neurons	neuron	NOUN
bptjm-29	50	21	,	,	PUNCT
bptjm-29	50	22	and	and	CCONJ
bptjm-29	50	23	rebuild	rebuild	VERB
bptjm-29	50	24	the	the	DET
bptjm-29	50	25	brain	brain	NOUN
bptjm-29	50	26	-	-	PUNCT
bptjm-29	50	27	to	to	ADP
bptjm-29	50	28	-	-	PUNCT
bptjm-29	50	29	muscle	muscle	NOUN
bptjm-29	50	30	connectivity10	connectivity10	NOUN
bptjm-29	50	31	.	.	PUNCT
bptjm-29	51	1	this	this	DET
bptjm-29	51	2	review	review	NOUN
bptjm-29	51	3	o	o	NOUN
bptjm-29	51	4	�	�	NOUN
bptjm-29	51	5	ers	er	NOUN
bptjm-29	51	6	insight	insight	VERB
bptjm-29	51	7	into	into	ADP
bptjm-29	51	8	the	the	DET
bptjm-29	51	9	di	di	NOUN
bptjm-29	51	10	�	�	PROPN
bptjm-29	51	11	erent	erent	NOUN
bptjm-29	51	12	pathogenetic	pathogenetic	ADJ
bptjm-29	51	13	mechanisms	mechanism	NOUN
bptjm-29	51	14	of	of	ADP
bptjm-29	51	15	als	al	NOUN
bptjm-29	51	16	,	,	PUNCT
bptjm-29	51	17	current	current	ADJ
bptjm-29	51	18	treatment	treatment	NOUN
bptjm-29	51	19	options	option	NOUN
bptjm-29	51	20	,	,	PUNCT
bptjm-29	51	21	and	and	CCONJ
bptjm-29	51	22	why	why	SCONJ
bptjm-29	51	23	mscs	msc	NOUN
bptjm-29	51	24	might	might	AUX
bptjm-29	51	25	o	o	VERB
bptjm-29	51	26	�	�	VERB
bptjm-29	51	27	er	er	INTJ
bptjm-29	51	28	a	a	DET
bptjm-29	51	29	cure	cure	NOUN
bptjm-29	51	30	.	.	PUNCT
bptjm-29	52	1	2	2	X
bptjm-29	52	2	.	.	X
bptjm-29	52	3	the	the	DET
bptjm-29	52	4	pathogenetic	pathogenetic	ADJ
bptjm-29	52	5	mechanisms	mechanism	NOUN
bptjm-29	52	6	of	of	ADP
bptjm-29	52	7	als	als	NOUN
bptjm-29	52	8	2.1	2.1	NUM
bptjm-29	52	9	.	.	PUNCT
bptjm-29	53	1	mitochondrial	mitochondrial	ADJ
bptjm-29	53	2	dysfunction	dysfunction	NOUN
bptjm-29	53	3	there	there	PRON
bptjm-29	53	4	are	be	VERB
bptjm-29	53	5	a	a	DET
bptjm-29	53	6	few	few	ADJ
bptjm-29	53	7	pathogenetic	pathogenetic	ADJ
bptjm-29	53	8	mechanisms	mechanism	NOUN
bptjm-29	53	9	that	that	PRON
bptjm-29	53	10	may	may	AUX
bptjm-29	53	11	explain	explain	VERB
bptjm-29	53	12	the	the	DET
bptjm-29	53	13	disease	disease	NOUN
bptjm-29	53	14	progression	progression	NOUN
bptjm-29	53	15	.	.	PUNCT
bptjm-29	54	1	of	of	ADP
bptjm-29	54	2	those	those	PRON
bptjm-29	54	3	,	,	PUNCT
bptjm-29	54	4	mitochondrial	mitochondrial	ADJ
bptjm-29	54	5	damage	damage	NOUN
bptjm-29	54	6	is	be	AUX
bptjm-29	54	7	an	an	DET
bptjm-29	54	8	important	important	ADJ
bptjm-29	54	9	pathogenetic	pathogenetic	ADJ
bptjm-29	54	10	mechanism	mechanism	NOUN
bptjm-29	54	11	to	to	PART
bptjm-29	54	12	consider	consider	VERB
bptjm-29	54	13	.	.	PUNCT
bptjm-29	55	1	mitochondria	mitochondria	PROPN
bptjm-29	55	2	is	be	AUX
bptjm-29	55	3	the	the	DET
bptjm-29	55	4	major	major	ADJ
bptjm-29	55	5	organelle	organelle	NOUN
bptjm-29	55	6	responsible	responsible	ADJ
bptjm-29	55	7	for	for	ADP
bptjm-29	55	8	many	many	ADJ
bptjm-29	55	9	cellular	cellular	ADJ
bptjm-29	55	10	processes	process	NOUN
bptjm-29	55	11	such	such	ADJ
bptjm-29	55	12	as	as	ADP
bptjm-29	55	13	producing	produce	VERB
bptjm-29	55	14	energy	energy	NOUN
bptjm-29	55	15	,	,	PUNCT
bptjm-29	55	16	conducting	conduct	VERB
bptjm-29	55	17	cellular	cellular	ADJ
bptjm-29	55	18	respiration	respiration	NOUN
bptjm-29	55	19	,	,	PUNCT
bptjm-29	55	20	and	and	CCONJ
bptjm-29	55	21	maintaining	maintain	VERB
bptjm-29	55	22	calcium	calcium	NOUN
bptjm-29	55	23	homeostasis8	homeostasis8	NOUN
bptjm-29	55	24	.	.	PUNCT
bptjm-29	56	1	this	this	DET
bptjm-29	56	2	organelle	organelle	NOUN
bptjm-29	56	3	is	be	AUX
bptjm-29	56	4	also	also	ADV
bptjm-29	56	5	known	know	VERB
bptjm-29	56	6	to	to	PART
bptjm-29	56	7	play	play	VERB
bptjm-29	56	8	a	a	DET
bptjm-29	56	9	key	key	ADJ
bptjm-29	56	10	role	role	NOUN
bptjm-29	56	11	in	in	ADP
bptjm-29	56	12	the	the	DET
bptjm-29	56	13	process	process	NOUN
bptjm-29	56	14	of	of	ADP
bptjm-29	56	15	apoptosis	apoptosis	NOUN
bptjm-29	56	16	—	—	PUNCT
bptjm-29	56	17	a	a	DET
bptjm-29	56	18	type	type	NOUN
bptjm-29	56	19	of	of	ADP
bptjm-29	56	20	cell	cell	NOUN
bptjm-29	56	21	death	death	NOUN
bptjm-29	56	22	activated	activate	VERB
bptjm-29	56	23	by	by	ADP
bptjm-29	56	24	a	a	DET
bptjm-29	56	25	series	series	NOUN
bptjm-29	56	26	of	of	ADP
bptjm-29	56	27	molecular	molecular	ADJ
bptjm-29	56	28	steps	step	NOUN
bptjm-29	56	29	known	know	VERB
bptjm-29	56	30	as	as	ADP
bptjm-29	56	31	the	the	DET
bptjm-29	56	32	caspase	caspase	NOUN
bptjm-29	56	33	cascade	cascade	NOUN
bptjm-29	56	34	.	.	PUNCT
bptjm-29	57	1	this	this	DET
bptjm-29	57	2	pathway	pathway	NOUN
bptjm-29	57	3	is	be	AUX
bptjm-29	57	4	often	often	ADV
bptjm-29	57	5	used	use	VERB
bptjm-29	57	6	by	by	ADP
bptjm-29	57	7	the	the	DET
bptjm-29	57	8	body	body	NOUN
bptjm-29	57	9	to	to	PART
bptjm-29	57	10	remove	remove	VERB
bptjm-29	57	11	unneeded	unneeded	ADJ
bptjm-29	57	12	or	or	CCONJ
bptjm-29	57	13	abnormal	abnormal	ADJ
bptjm-29	57	14	cells11	cells11	NOUN
bptjm-29	57	15	.	.	PUNCT
bptjm-29	58	1	because	because	SCONJ
bptjm-29	58	2	the	the	DET
bptjm-29	58	3	mitochondria	mitochondria	NOUN
bptjm-29	58	4	play	play	VERB
bptjm-29	58	5	a	a	DET
bptjm-29	58	6	key	key	ADJ
bptjm-29	58	7	role	role	NOUN
bptjm-29	58	8	in	in	ADP
bptjm-29	58	9	regulating	regulate	VERB
bptjm-29	58	10	apoptosis	apoptosis	NOUN
bptjm-29	58	11	,	,	PUNCT
bptjm-29	58	12	damage	damage	NOUN
bptjm-29	58	13	to	to	ADP
bptjm-29	58	14	this	this	DET
bptjm-29	58	15	organelle	organelle	NOUN
bptjm-29	58	16	within	within	ADP
bptjm-29	58	17	motor	motor	NOUN
bptjm-29	58	18	neurons	neuron	NOUN
bptjm-29	58	19	can	can	AUX
bptjm-29	58	20	alter	alter	VERB
bptjm-29	58	21	its	its	PRON
bptjm-29	58	22	ability	ability	NOUN
bptjm-29	58	23	to	to	PART
bptjm-29	58	24	regulate	regulate	VERB
bptjm-29	58	25	the	the	DET
bptjm-29	58	26	process	process	NOUN
bptjm-29	58	27	.	.	PUNCT
bptjm-29	59	1	in	in	ADP
bptjm-29	59	2	als	als	NOUN
bptjm-29	59	3	patients	patient	NOUN
bptjm-29	59	4	,	,	PUNCT
bptjm-29	59	5	the	the	DET
bptjm-29	59	6	mitochondria	mitochondria	NOUN
bptjm-29	59	7	that	that	PRON
bptjm-29	59	8	are	be	AUX
bptjm-29	59	9	present	present	ADJ
bptjm-29	59	10	in	in	ADP
bptjm-29	59	11	their	their	PRON
bptjm-29	59	12	spinal	spinal	ADJ
bptjm-29	59	13	motor	motor	NOUN
bptjm-29	59	14	neurons	neuron	NOUN
bptjm-29	59	15	,	,	PUNCT
bptjm-29	59	16	skeletal	skeletal	ADJ
bptjm-29	59	17	muscles	muscle	NOUN
bptjm-29	59	18	,	,	PUNCT
bptjm-29	59	19	and	and	CCONJ
bptjm-29	59	20	intramuscular	intramuscular	ADJ
bptjm-29	59	21	nerves	nerve	NOUN
bptjm-29	59	22	are	be	AUX
bptjm-29	59	23	swollen	swollen	ADJ
bptjm-29	59	24	and	and	CCONJ
bptjm-29	59	25	vacuolated	vacuolate	VERB
bptjm-29	59	26	.	.	PUNCT
bptjm-29	60	1	speci	speci	PROPN
bptjm-29	60	2	�	�	PROPN
bptjm-29	60	3	cally	cally	ADV
bptjm-29	60	4	,	,	PUNCT
bptjm-29	60	5	these	these	DET
bptjm-29	60	6	swollen	swollen	ADJ
bptjm-29	60	7	mitochondria	mitochondria	NOUN
bptjm-29	60	8	activate	activate	VERB
bptjm-29	60	9	the	the	DET
bptjm-29	60	10	apoptotic	apoptotic	ADJ
bptjm-29	60	11	caspase	caspase	NOUN
bptjm-29	60	12	cascade	cascade	NOUN
bptjm-29	60	13	,	,	PUNCT
bptjm-29	60	14	causing	cause	VERB
bptjm-29	60	15	the	the	DET
bptjm-29	60	16	death	death	NOUN
bptjm-29	60	17	of	of	ADP
bptjm-29	60	18	the	the	DET
bptjm-29	60	19	motor	motor	PROPN
bptjm-29	60	20	neurons12	neurons12	PROPN
bptjm-29	60	21	.	.	PUNCT
bptjm-29	61	1	berkeley	berkeley	PROPN
bptjm-29	61	2	pharma	pharma	PROPN
bptjm-29	61	3	tech	tech	PROPN
bptjm-29	61	4	journal	journal	NOUN
bptjm-29	61	5	of	of	ADP
bptjm-29	61	6	medicine	medicine	NOUN
bptjm-29	61	7	|	|	ADV
bptjm-29	61	8	73	73	NUM
bptjm-29	61	9	https://www.zotero.org/google-docs/?yu8gsj	https://www.zotero.org/google-docs/?yu8gsj	NUM
bptjm-29	61	10	https://www.zotero.org/google-docs/?qetopm	https://www.zotero.org/google-docs/?qetopm	NOUN
bptjm-29	61	11	https://www.zotero.org/google-docs/?f2vwug	https://www.zotero.org/google-docs/?f2vwug	VERB
bptjm-29	61	12	https://www.zotero.org/google-docs/?zb1ptl	https://www.zotero.org/google-docs/?zb1ptl	NOUN
bptjm-29	61	13	additionally	additionally	ADV
bptjm-29	61	14	,	,	PUNCT
bptjm-29	61	15	deposits	deposit	NOUN
bptjm-29	61	16	of	of	ADP
bptjm-29	61	17	the	the	DET
bptjm-29	61	18	misfolded	misfolded	ADJ
bptjm-29	61	19	sod1	sod1	ADJ
bptjm-29	61	20	enzymes	enzyme	NOUN
bptjm-29	61	21	and	and	CCONJ
bptjm-29	61	22	altered	alter	VERB
bptjm-29	61	23	protein	protein	NOUN
bptjm-29	61	24	expression	expression	NOUN
bptjm-29	61	25	in	in	ADP
bptjm-29	61	26	the	the	DET
bptjm-29	61	27	mitochondria	mitochondria	NOUN
bptjm-29	61	28	further	far	ADV
bptjm-29	61	29	alter	alter	VERB
bptjm-29	61	30	the	the	DET
bptjm-29	61	31	physiological	physiological	ADJ
bptjm-29	61	32	function	function	NOUN
bptjm-29	61	33	of	of	ADP
bptjm-29	61	34	the	the	DET
bptjm-29	61	35	organelle9	organelle9	NOUN
bptjm-29	61	36	.	.	PUNCT
bptjm-29	62	1	a	a	PRON
bptjm-29	62	2	de	de	X
bptjm-29	62	3	�	�	NOUN
bptjm-29	62	4	cit	cit	PROPN
bptjm-29	62	5	in	in	ADP
bptjm-29	62	6	atp	atp	PROPN
bptjm-29	62	7	production	production	NOUN
bptjm-29	62	8	a	a	DET
bptjm-29	62	9	�	�	NOUN
bptjm-29	62	10	ects	ect	VERB
bptjm-29	62	11	the	the	DET
bptjm-29	62	12	cell	cell	NOUN
bptjm-29	62	13	’s	’s	PART
bptjm-29	62	14	energy	energy	NOUN
bptjm-29	62	15	homeostasis	homeostasis	NOUN
bptjm-29	62	16	and	and	CCONJ
bptjm-29	62	17	causes	cause	VERB
bptjm-29	62	18	a	a	DET
bptjm-29	62	19	defective	defective	ADJ
bptjm-29	62	20	energy	energy	NOUN
bptjm-29	62	21	metabolism	metabolism	NOUN
bptjm-29	62	22	.	.	PUNCT
bptjm-29	63	1	alterations	alteration	NOUN
bptjm-29	63	2	in	in	ADP
bptjm-29	63	3	the	the	DET
bptjm-29	63	4	energy	energy	NOUN
bptjm-29	63	5	metabolism	metabolism	NOUN
bptjm-29	63	6	weaken	weaken	VERB
bptjm-29	63	7	the	the	DET
bptjm-29	63	8	cell	cell	NOUN
bptjm-29	63	9	’s	’s	PART
bptjm-29	63	10	health	health	NOUN
bptjm-29	63	11	.	.	PUNCT
bptjm-29	64	1	mitochondria	mitochondria	PROPN
bptjm-29	64	2	with	with	ADP
bptjm-29	64	3	an	an	DET
bptjm-29	64	4	altered	altered	ADJ
bptjm-29	64	5	structure	structure	NOUN
bptjm-29	64	6	or	or	CCONJ
bptjm-29	64	7	biochemical	biochemical	ADJ
bptjm-29	64	8	imbalance	imbalance	NOUN
bptjm-29	64	9	are	be	AUX
bptjm-29	64	10	prone	prone	ADJ
bptjm-29	64	11	to	to	ADP
bptjm-29	64	12	triggering	trigger	VERB
bptjm-29	64	13	apoptosis	apoptosis	NOUN
bptjm-29	64	14	,	,	PUNCT
bptjm-29	64	15	thus	thus	ADV
bptjm-29	64	16	leading	lead	VERB
bptjm-29	64	17	to	to	ADP
bptjm-29	64	18	neuronal	neuronal	ADJ
bptjm-29	64	19	degeneration	degeneration	NOUN
bptjm-29	64	20	.	.	PUNCT
bptjm-29	65	1	mitochondria	mitochondria	PROPN
bptjm-29	65	2	are	be	AUX
bptjm-29	65	3	responsible	responsible	ADJ
bptjm-29	65	4	for	for	ADP
bptjm-29	65	5	regulating	regulate	VERB
bptjm-29	65	6	calcium	calcium	NOUN
bptjm-29	65	7	levels	level	NOUN
bptjm-29	65	8	as	as	ADV
bptjm-29	65	9	well	well	ADV
bptjm-29	65	10	.	.	PUNCT
bptjm-29	66	1	in	in	ADP
bptjm-29	66	2	als	als	NOUN
bptjm-29	66	3	models	model	NOUN
bptjm-29	66	4	,	,	PUNCT
bptjm-29	66	5	scientists	scientist	NOUN
bptjm-29	66	6	have	have	AUX
bptjm-29	66	7	reported	report	VERB
bptjm-29	66	8	dysregulation	dysregulation	NOUN
bptjm-29	66	9	of	of	ADP
bptjm-29	66	10	intracellular	intracellular	ADJ
bptjm-29	66	11	ca2	ca2	PROPN
bptjm-29	66	12	+	+	X
bptjm-29	66	13	in	in	ADP
bptjm-29	66	14	motor	motor	NOUN
bptjm-29	66	15	neurons	neuron	NOUN
bptjm-29	66	16	.	.	PUNCT
bptjm-29	67	1	chronic	chronic	ADJ
bptjm-29	67	2	elevations	elevation	NOUN
bptjm-29	67	3	of	of	ADP
bptjm-29	67	4	cytosolic	cytosolic	ADJ
bptjm-29	67	5	ca2	ca2	PROPN
bptjm-29	67	6	+	+	PROPN
bptjm-29	67	7	due	due	ADP
bptjm-29	67	8	to	to	ADP
bptjm-29	67	9	neuronal	neuronal	ADJ
bptjm-29	67	10	hyperexcitability	hyperexcitability	NOUN
bptjm-29	67	11	elicit	elicit	VERB
bptjm-29	67	12	an	an	DET
bptjm-29	67	13	increase	increase	NOUN
bptjm-29	67	14	in	in	ADP
bptjm-29	67	15	mitochondrial	mitochondrial	ADJ
bptjm-29	67	16	ca2	ca2	PROPN
bptjm-29	67	17	+	+	CCONJ
bptjm-29	67	18	uptake	uptake	ADJ
bptjm-29	67	19	and	and	CCONJ
bptjm-29	67	20	a	a	DET
bptjm-29	67	21	decrease	decrease	NOUN
bptjm-29	67	22	in	in	ADP
bptjm-29	67	23	mitochondrial	mitochondrial	ADJ
bptjm-29	67	24	ca2	ca2	PROPN
bptjm-29	67	25	+	+	PROPN
bptjm-29	67	26	e	e	PROPN
bptjm-29	67	27	�	�	PROPN
bptjm-29	67	28	ux	ux	NOUN
bptjm-29	67	29	.	.	PUNCT
bptjm-29	68	1	when	when	SCONJ
bptjm-29	68	2	this	this	DET
bptjm-29	68	3	condition	condition	NOUN
bptjm-29	68	4	is	be	AUX
bptjm-29	68	5	combined	combine	VERB
bptjm-29	68	6	with	with	ADP
bptjm-29	68	7	altered	altered	ADJ
bptjm-29	68	8	mitochondrial	mitochondrial	ADJ
bptjm-29	68	9	calcium	calcium	NOUN
bptjm-29	68	10	regulation	regulation	NOUN
bptjm-29	68	11	,	,	PUNCT
bptjm-29	68	12	excitatory	excitatory	ADJ
bptjm-29	68	13	mitochondrial	mitochondrial	ADJ
bptjm-29	68	14	toxicity	toxicity	NOUN
bptjm-29	68	15	occurs	occur	VERB
bptjm-29	68	16	,	,	PUNCT
bptjm-29	68	17	leading	lead	VERB
bptjm-29	68	18	to	to	ADP
bptjm-29	68	19	dendritic	dendritic	ADJ
bptjm-29	68	20	mitophagy	mitophagy	NOUN
bptjm-29	68	21	,	,	PUNCT
bptjm-29	68	22	mitochondrial	mitochondrial	ADJ
bptjm-29	68	23	depletion	depletion	NOUN
bptjm-29	68	24	,	,	PUNCT
bptjm-29	68	25	and	and	CCONJ
bptjm-29	68	26	eventually	eventually	ADV
bptjm-29	68	27	dendritic	dendritic	ADJ
bptjm-29	68	28	atrophy	atrophy	NOUN
bptjm-29	68	29	and	and	CCONJ
bptjm-29	68	30	neurodegeneration13	neurodegeneration13	NOUN
bptjm-29	68	31	.	.	PUNCT
bptjm-29	69	1	overall	overall	ADV
bptjm-29	69	2	,	,	PUNCT
bptjm-29	69	3	ca2	ca2	PROPN
bptjm-29	69	4	+	+	PROPN
bptjm-29	69	5	dysregulation	dysregulation	NOUN
bptjm-29	69	6	in	in	ADP
bptjm-29	69	7	motor	motor	NOUN
bptjm-29	69	8	neurons	neuron	NOUN
bptjm-29	69	9	is	be	AUX
bptjm-29	69	10	at	at	ADP
bptjm-29	69	11	the	the	DET
bptjm-29	69	12	cornerstone	cornerstone	NOUN
bptjm-29	69	13	of	of	ADP
bptjm-29	69	14	disease	disease	NOUN
bptjm-29	69	15	progression	progression	NOUN
bptjm-29	69	16	of	of	ADP
bptjm-29	69	17	als13	als13	PROPN
bptjm-29	69	18	.	.	PUNCT
bptjm-29	70	1	2.2	2.2	NUM
bptjm-29	70	2	.	.	PUNCT
bptjm-29	70	3	glutamate	glutamate	VERB
bptjm-29	70	4	excitotoxicity	excitotoxicity	NOUN
bptjm-29	70	5	glutamate	glutamate	NOUN
bptjm-29	70	6	excitotoxicity	excitotoxicity	NOUN
bptjm-29	70	7	is	be	AUX
bptjm-29	70	8	another	another	DET
bptjm-29	70	9	pathogenetic	pathogenetic	ADJ
bptjm-29	70	10	mechanism	mechanism	NOUN
bptjm-29	70	11	that	that	PRON
bptjm-29	70	12	can	can	AUX
bptjm-29	70	13	provide	provide	VERB
bptjm-29	70	14	an	an	DET
bptjm-29	70	15	explanation	explanation	NOUN
bptjm-29	70	16	as	as	ADP
bptjm-29	70	17	to	to	ADP
bptjm-29	70	18	how	how	SCONJ
bptjm-29	70	19	motor	motor	NOUN
bptjm-29	70	20	neurons	neuron	NOUN
bptjm-29	70	21	degenerate	degenerate	VERB
bptjm-29	70	22	in	in	ADP
bptjm-29	70	23	als	als	NOUN
bptjm-29	70	24	patients	patient	NOUN
bptjm-29	70	25	.	.	PUNCT
bptjm-29	71	1	glutamate	glutamate	NOUN
bptjm-29	71	2	is	be	AUX
bptjm-29	71	3	a	a	DET
bptjm-29	71	4	principal	principal	ADJ
bptjm-29	71	5	excitatory	excitatory	NOUN
bptjm-29	71	6	neurotransmitter	neurotransmitter	NOUN
bptjm-29	71	7	in	in	ADP
bptjm-29	71	8	the	the	DET
bptjm-29	71	9	central	central	ADJ
bptjm-29	71	10	nervous	nervous	ADJ
bptjm-29	71	11	system	system	NOUN
bptjm-29	71	12	(	(	PUNCT
bptjm-29	71	13	cns	cns	NOUN
bptjm-29	71	14	)	)	PUNCT
bptjm-29	71	15	and	and	CCONJ
bptjm-29	71	16	plays	play	VERB
bptjm-29	71	17	a	a	DET
bptjm-29	71	18	key	key	ADJ
bptjm-29	71	19	role	role	NOUN
bptjm-29	71	20	in	in	ADP
bptjm-29	71	21	triggering	trigger	VERB
bptjm-29	71	22	action	action	NOUN
bptjm-29	71	23	potentials14	potentials14	NOUN
bptjm-29	71	24	.	.	PUNCT
bptjm-29	72	1	neurotransmitters	neurotransmitter	NOUN
bptjm-29	72	2	are	be	AUX
bptjm-29	72	3	chemical	chemical	ADJ
bptjm-29	72	4	messengers	messenger	NOUN
bptjm-29	72	5	that	that	PRON
bptjm-29	72	6	send	send	VERB
bptjm-29	72	7	signals	signal	NOUN
bptjm-29	72	8	from	from	ADP
bptjm-29	72	9	one	one	NUM
bptjm-29	72	10	nerve	nerve	NOUN
bptjm-29	72	11	cell	cell	NOUN
bptjm-29	72	12	to	to	ADP
bptjm-29	72	13	a	a	DET
bptjm-29	72	14	target	target	NOUN
bptjm-29	72	15	cell	cell	NOUN
bptjm-29	72	16	,	,	PUNCT
bptjm-29	72	17	which	which	PRON
bptjm-29	72	18	could	could	AUX
bptjm-29	72	19	be	be	AUX
bptjm-29	72	20	a	a	DET
bptjm-29	72	21	nerve	nerve	NOUN
bptjm-29	72	22	cell	cell	NOUN
bptjm-29	72	23	,	,	PUNCT
bptjm-29	72	24	a	a	DET
bptjm-29	72	25	motor	motor	NOUN
bptjm-29	72	26	cell	cell	NOUN
bptjm-29	72	27	,	,	PUNCT
bptjm-29	72	28	or	or	CCONJ
bptjm-29	72	29	a	a	DET
bptjm-29	72	30	gland15	gland15	NOUN
bptjm-29	72	31	.	.	PUNCT
bptjm-29	73	1	glutamate	glutamate	NOUN
bptjm-29	73	2	sends	send	VERB
bptjm-29	73	3	signals	signal	NOUN
bptjm-29	73	4	within	within	ADP
bptjm-29	73	5	the	the	DET
bptjm-29	73	6	cns	cns	NOUN
bptjm-29	73	7	,	,	PUNCT
bptjm-29	73	8	which	which	PRON
bptjm-29	73	9	is	be	AUX
bptjm-29	73	10	made	make	VERB
bptjm-29	73	11	up	up	ADP
bptjm-29	73	12	of	of	ADP
bptjm-29	73	13	the	the	DET
bptjm-29	73	14	brain	brain	NOUN
bptjm-29	73	15	and	and	CCONJ
bptjm-29	73	16	spinal	spinal	ADJ
bptjm-29	73	17	cord	cord	NOUN
bptjm-29	73	18	.	.	PUNCT
bptjm-29	74	1	this	this	DET
bptjm-29	74	2	neurotransmitter	neurotransmitter	NOUN
bptjm-29	74	3	is	be	AUX
bptjm-29	74	4	originally	originally	ADV
bptjm-29	74	5	generated	generate	VERB
bptjm-29	74	6	in	in	ADP
bptjm-29	74	7	the	the	DET
bptjm-29	74	8	presynaptic	presynaptic	ADJ
bptjm-29	74	9	cleft	cleft	NOUN
bptjm-29	74	10	terminal	terminal	NOUN
bptjm-29	74	11	,	,	PUNCT
bptjm-29	74	12	exits	exit	VERB
bptjm-29	74	13	through	through	ADP
bptjm-29	74	14	exocytosis	exocytosis	NOUN
bptjm-29	74	15	,	,	PUNCT
bptjm-29	74	16	then	then	ADV
bptjm-29	74	17	moves	move	VERB
bptjm-29	74	18	across	across	ADP
bptjm-29	74	19	the	the	DET
bptjm-29	74	20	synaptic	synaptic	ADJ
bptjm-29	74	21	cleft	cleft	NOUN
bptjm-29	74	22	in	in	ADP
bptjm-29	74	23	order	order	NOUN
bptjm-29	74	24	to	to	PART
bptjm-29	74	25	activate	activate	VERB
bptjm-29	74	26	postsynaptic	postsynaptic	ADJ
bptjm-29	74	27	receptors	receptor	NOUN
bptjm-29	74	28	in	in	ADP
bptjm-29	74	29	the	the	DET
bptjm-29	74	30	dendrites	dendrite	NOUN
bptjm-29	74	31	of	of	ADP
bptjm-29	74	32	postsynaptic	postsynaptic	ADJ
bptjm-29	74	33	motor	motor	NOUN
bptjm-29	74	34	neurons	neuron	NOUN
bptjm-29	74	35	,	,	PUNCT
bptjm-29	74	36	which	which	PRON
bptjm-29	74	37	triggers	trigger	VERB
bptjm-29	74	38	action	action	NOUN
bptjm-29	74	39	potentials16,17	potentials16,17	NOUN
bptjm-29	74	40	.	.	PUNCT
bptjm-29	75	1	the	the	DET
bptjm-29	75	2	synaptic	synaptic	ADJ
bptjm-29	75	3	cleft	cleft	NOUN
bptjm-29	75	4	is	be	AUX
bptjm-29	75	5	the	the	DET
bptjm-29	75	6	space	space	NOUN
bptjm-29	75	7	neurotransmitters	neurotransmitter	NOUN
bptjm-29	75	8	travel	travel	VERB
bptjm-29	75	9	through	through	ADP
bptjm-29	75	10	to	to	PART
bptjm-29	75	11	send	send	VERB
bptjm-29	75	12	messages	message	NOUN
bptjm-29	75	13	from	from	ADP
bptjm-29	75	14	one	one	NUM
bptjm-29	75	15	neuron	neuron	NOUN
bptjm-29	75	16	to	to	ADP
bptjm-29	75	17	the	the	DET
bptjm-29	75	18	next	next	ADJ
bptjm-29	75	19	.	.	PUNCT
bptjm-29	76	1	glutamate	glutamate	ADJ
bptjm-29	76	2	reuptake	reuptake	NOUN
bptjm-29	76	3	transporters	transporter	NOUN
bptjm-29	76	4	remove	remove	VERB
bptjm-29	76	5	glutamate	glutamate	NOUN
bptjm-29	76	6	from	from	ADP
bptjm-29	76	7	the	the	DET
bptjm-29	76	8	synaptic	synaptic	ADJ
bptjm-29	76	9	cleft	cleft	NOUN
bptjm-29	76	10	to	to	PART
bptjm-29	76	11	regulate	regulate	VERB
bptjm-29	76	12	the	the	DET
bptjm-29	76	13	concentration	concentration	NOUN
bptjm-29	76	14	of	of	ADP
bptjm-29	76	15	the	the	DET
bptjm-29	76	16	neurotransmitter	neurotransmitter	NOUN
bptjm-29	76	17	in	in	ADP
bptjm-29	76	18	the	the	DET
bptjm-29	76	19	synaptic	synaptic	ADJ
bptjm-29	76	20	cleft	cleft	NOUN
bptjm-29	76	21	,	,	PUNCT
bptjm-29	76	22	berkeley	berkeley	PROPN
bptjm-29	76	23	pharma	pharma	PROPN
bptjm-29	76	24	tech	tech	NOUN
bptjm-29	76	25	journal	journal	NOUN
bptjm-29	76	26	of	of	ADP
bptjm-29	76	27	medicine	medicine	NOUN
bptjm-29	76	28	|	|	ADV
bptjm-29	76	29	74	74	NUM
bptjm-29	76	30	https://www.zotero.org/google-docs/?hsgu91	https://www.zotero.org/google-docs/?hsgu91	NOUN
bptjm-29	76	31	https://www.zotero.org/google-docs/?iqrupn	https://www.zotero.org/google-docs/?iqrupn	NOUN
bptjm-29	76	32	https://www.zotero.org/google-docs/?qbb4hd	https://www.zotero.org/google-docs/?qbb4hd	VERB
bptjm-29	77	1	https://www.zotero.org/google-docs/?tz405s	https://www.zotero.org/google-docs/?tz405s	NOUN
bptjm-29	77	2	https://www.zotero.org/google-docs/?809vuj	https://www.zotero.org/google-docs/?809vuj	PRON
bptjm-29	77	3	getting	getting	AUX
bptjm-29	77	4	rid	rid	VERB
bptjm-29	77	5	of	of	ADP
bptjm-29	77	6	excitatory	excitatory	NOUN
bptjm-29	77	7	stimuli	stimulus	NOUN
bptjm-29	77	8	along	along	ADP
bptjm-29	77	9	with	with	ADP
bptjm-29	77	10	it16	it16	PROPN
bptjm-29	77	11	.	.	PUNCT
bptjm-29	78	1	high	high	ADJ
bptjm-29	78	2	glutamate	glutamate	NOUN
bptjm-29	78	3	concentration	concentration	NOUN
bptjm-29	78	4	in	in	ADP
bptjm-29	78	5	the	the	DET
bptjm-29	78	6	synaptic	synaptic	ADJ
bptjm-29	78	7	cleft	cleft	NOUN
bptjm-29	78	8	leads	lead	VERB
bptjm-29	78	9	to	to	ADP
bptjm-29	78	10	excitotoxicity	excitotoxicity	NOUN
bptjm-29	78	11	,	,	PUNCT
bptjm-29	78	12	which	which	PRON
bptjm-29	78	13	can	can	AUX
bptjm-29	78	14	either	either	CCONJ
bptjm-29	78	15	result	result	VERB
bptjm-29	78	16	from	from	ADP
bptjm-29	78	17	increased	increase	VERB
bptjm-29	78	18	synaptic	synaptic	ADJ
bptjm-29	78	19	levels	level	NOUN
bptjm-29	78	20	of	of	ADP
bptjm-29	78	21	glutamate	glutamate	NOUN
bptjm-29	78	22	or	or	CCONJ
bptjm-29	78	23	greater	great	ADJ
bptjm-29	78	24	glutamate	glutamate	ADJ
bptjm-29	78	25	sensitivity	sensitivity	NOUN
bptjm-29	78	26	in	in	ADP
bptjm-29	78	27	the	the	DET
bptjm-29	78	28	postsynaptic	postsynaptic	ADJ
bptjm-29	78	29	terminal9	terminal9	NOUN
bptjm-29	78	30	.	.	PUNCT
bptjm-29	79	1	overall	overall	ADV
bptjm-29	79	2	,	,	PUNCT
bptjm-29	79	3	excitotoxicity	excitotoxicity	NOUN
bptjm-29	79	4	occurs	occur	VERB
bptjm-29	79	5	due	due	ADJ
bptjm-29	79	6	to	to	ADP
bptjm-29	79	7	prolonged	prolonged	ADJ
bptjm-29	79	8	activation	activation	NOUN
bptjm-29	79	9	of	of	ADP
bptjm-29	79	10	glutamate	glutamate	ADJ
bptjm-29	79	11	receptors	receptor	NOUN
bptjm-29	79	12	,	,	PUNCT
bptjm-29	79	13	which	which	PRON
bptjm-29	79	14	eventually	eventually	ADV
bptjm-29	79	15	leads	lead	VERB
bptjm-29	79	16	to	to	ADP
bptjm-29	79	17	the	the	DET
bptjm-29	79	18	degeneration	degeneration	NOUN
bptjm-29	79	19	and	and	CCONJ
bptjm-29	79	20	death	death	NOUN
bptjm-29	79	21	of	of	ADP
bptjm-29	79	22	the	the	DET
bptjm-29	79	23	motor	motor	NOUN
bptjm-29	79	24	neurons	neuron	NOUN
bptjm-29	79	25	involved	involve	VERB
bptjm-29	79	26	,	,	PUNCT
bptjm-29	79	27	induced	induce	VERB
bptjm-29	79	28	through	through	ADP
bptjm-29	79	29	excessive	excessive	ADJ
bptjm-29	79	30	neuronal	neuronal	ADJ
bptjm-29	79	31	�	�	PROPN
bptjm-29	79	32	ring18	ring18	NOUN
bptjm-29	79	33	.	.	PUNCT
bptjm-29	80	1	als	als	NOUN
bptjm-29	80	2	patients	patient	NOUN
bptjm-29	80	3	reported	report	VERB
bptjm-29	80	4	having	have	VERB
bptjm-29	80	5	lower	low	ADJ
bptjm-29	80	6	levels	level	NOUN
bptjm-29	80	7	of	of	ADP
bptjm-29	80	8	glutamate	glutamate	ADJ
bptjm-29	80	9	transporters	transporter	NOUN
bptjm-29	80	10	,	,	PUNCT
bptjm-29	80	11	which	which	PRON
bptjm-29	80	12	leads	lead	VERB
bptjm-29	80	13	to	to	ADP
bptjm-29	80	14	an	an	DET
bptjm-29	80	15	increased	increase	VERB
bptjm-29	80	16	concentration	concentration	NOUN
bptjm-29	80	17	of	of	ADP
bptjm-29	80	18	this	this	DET
bptjm-29	80	19	neurotransmitter	neurotransmitter	NOUN
bptjm-29	80	20	in	in	ADP
bptjm-29	80	21	the	the	DET
bptjm-29	80	22	synaptic	synaptic	ADJ
bptjm-29	80	23	cleft	cleft	NOUN
bptjm-29	80	24	and	and	CCONJ
bptjm-29	80	25	an	an	DET
bptjm-29	80	26	overactivation	overactivation	NOUN
bptjm-29	80	27	of	of	ADP
bptjm-29	80	28	glutamate	glutamate	ADJ
bptjm-29	80	29	receptors	receptor	NOUN
bptjm-29	80	30	,	,	PUNCT
bptjm-29	80	31	determining	determine	VERB
bptjm-29	80	32	the	the	DET
bptjm-29	80	33	level	level	NOUN
bptjm-29	80	34	of	of	ADP
bptjm-29	80	35	excitotoxicity	excitotoxicity	NOUN
bptjm-29	80	36	within	within	ADP
bptjm-29	80	37	the	the	DET
bptjm-29	80	38	neurons7	neurons7	PROPN
bptjm-29	80	39	.	.	PUNCT
bptjm-29	81	1	as	as	ADP
bptjm-29	81	2	a	a	DET
bptjm-29	81	3	key	key	ADJ
bptjm-29	81	4	regulator	regulator	NOUN
bptjm-29	81	5	of	of	ADP
bptjm-29	81	6	neuronal	neuronal	ADJ
bptjm-29	81	7	activity	activity	NOUN
bptjm-29	81	8	due	due	ADP
bptjm-29	81	9	to	to	ADP
bptjm-29	81	10	the	the	DET
bptjm-29	81	11	role	role	NOUN
bptjm-29	81	12	it	it	PRON
bptjm-29	81	13	plays	play	VERB
bptjm-29	81	14	in	in	ADP
bptjm-29	81	15	apoptosis	apoptosis	NOUN
bptjm-29	81	16	and	and	CCONJ
bptjm-29	81	17	neurotransmitter	neurotransmitter	NOUN
bptjm-29	81	18	release	release	NOUN
bptjm-29	81	19	,	,	PUNCT
bptjm-29	81	20	calcium	calcium	NOUN
bptjm-29	81	21	plays	play	VERB
bptjm-29	81	22	an	an	DET
bptjm-29	81	23	important	important	ADJ
bptjm-29	81	24	role	role	NOUN
bptjm-29	81	25	in	in	ADP
bptjm-29	81	26	excitotoxicity19	excitotoxicity19	NOUN
bptjm-29	81	27	.	.	PUNCT
bptjm-29	82	1	the	the	DET
bptjm-29	82	2	activation	activation	NOUN
bptjm-29	82	3	of	of	ADP
bptjm-29	82	4	glutamate	glutamate	ADJ
bptjm-29	82	5	receptors	receptor	NOUN
bptjm-29	82	6	opens	open	VERB
bptjm-29	82	7	calcium	calcium	NOUN
bptjm-29	82	8	channels	channel	NOUN
bptjm-29	82	9	,	,	PUNCT
bptjm-29	82	10	allowing	allow	VERB
bptjm-29	82	11	calcium	calcium	NOUN
bptjm-29	82	12	to	to	PART
bptjm-29	82	13	enter	enter	VERB
bptjm-29	82	14	the	the	DET
bptjm-29	82	15	cell	cell	NOUN
bptjm-29	82	16	.	.	PUNCT
bptjm-29	83	1	the	the	DET
bptjm-29	83	2	calcium	calcium	NOUN
bptjm-29	83	3	-	-	PUNCT
bptjm-29	83	4	bu	bu	NOUN
bptjm-29	83	5	�	�	NOUN
bptjm-29	83	6	ering	ere	VERB
bptjm-29	83	7	proteins	protein	NOUN
bptjm-29	83	8	in	in	ADP
bptjm-29	83	9	motor	motor	NOUN
bptjm-29	83	10	neurons	neuron	NOUN
bptjm-29	83	11	make	make	VERB
bptjm-29	83	12	motor	motor	NOUN
bptjm-29	83	13	neurons	neuron	NOUN
bptjm-29	83	14	sensitive	sensitive	ADJ
bptjm-29	83	15	to	to	ADP
bptjm-29	83	16	excitotoxicity	excitotoxicity	NOUN
bptjm-29	83	17	.	.	PUNCT
bptjm-29	84	1	if	if	SCONJ
bptjm-29	84	2	intracellular	intracellular	ADJ
bptjm-29	84	3	calcium	calcium	NOUN
bptjm-29	84	4	levels	level	NOUN
bptjm-29	84	5	get	get	VERB
bptjm-29	84	6	too	too	ADV
bptjm-29	84	7	high	high	ADJ
bptjm-29	84	8	,	,	PUNCT
bptjm-29	84	9	mitochondrial	mitochondrial	ADJ
bptjm-29	84	10	damage	damage	NOUN
bptjm-29	84	11	may	may	AUX
bptjm-29	84	12	result	result	VERB
bptjm-29	84	13	and	and	CCONJ
bptjm-29	84	14	lead	lead	VERB
bptjm-29	84	15	to	to	ADP
bptjm-29	84	16	the	the	DET
bptjm-29	84	17	activation	activation	NOUN
bptjm-29	84	18	of	of	ADP
bptjm-29	84	19	biochemical	biochemical	ADJ
bptjm-29	84	20	processes	process	NOUN
bptjm-29	84	21	that	that	PRON
bptjm-29	84	22	a	a	DET
bptjm-29	84	23	�	�	NOUN
bptjm-29	84	24	ect	ect	VERB
bptjm-29	84	25	neuronal	neuronal	ADJ
bptjm-29	84	26	degeneration13	degeneration13	NOUN
bptjm-29	84	27	.	.	PUNCT
bptjm-29	85	1	additionally	additionally	ADV
bptjm-29	85	2	,	,	PUNCT
bptjm-29	85	3	motor	motor	NOUN
bptjm-29	85	4	neurons	neuron	NOUN
bptjm-29	85	5	are	be	AUX
bptjm-29	85	6	especially	especially	ADV
bptjm-29	85	7	sensitive	sensitive	ADJ
bptjm-29	85	8	to	to	ADP
bptjm-29	85	9	excitotoxicity	excitotoxicity	NOUN
bptjm-29	85	10	due	due	ADP
bptjm-29	85	11	to	to	ADP
bptjm-29	85	12	the	the	DET
bptjm-29	85	13	high	high	ADJ
bptjm-29	85	14	calcium	calcium	NOUN
bptjm-29	85	15	permeability	permeability	NOUN
bptjm-29	85	16	of	of	ADP
bptjm-29	85	17	these	these	DET
bptjm-29	85	18	cells13	cells13	NOUN
bptjm-29	85	19	.	.	PUNCT
bptjm-29	86	1	with	with	ADP
bptjm-29	86	2	more	more	ADJ
bptjm-29	86	3	calcium	calcium	NOUN
bptjm-29	86	4	able	able	ADJ
bptjm-29	86	5	to	to	PART
bptjm-29	86	6	enter	enter	VERB
bptjm-29	86	7	the	the	DET
bptjm-29	86	8	cells	cell	NOUN
bptjm-29	86	9	,	,	PUNCT
bptjm-29	86	10	intracellular	intracellular	ADJ
bptjm-29	86	11	calcium	calcium	NOUN
bptjm-29	86	12	levels	level	NOUN
bptjm-29	86	13	get	get	VERB
bptjm-29	86	14	high	high	ADJ
bptjm-29	86	15	and	and	CCONJ
bptjm-29	86	16	lead	lead	VERB
bptjm-29	86	17	to	to	ADP
bptjm-29	86	18	cell	cell	NOUN
bptjm-29	86	19	damage	damage	NOUN
bptjm-29	86	20	that	that	PRON
bptjm-29	86	21	induces	induce	VERB
bptjm-29	86	22	the	the	DET
bptjm-29	86	23	degeneration	degeneration	NOUN
bptjm-29	86	24	of	of	ADP
bptjm-29	86	25	motor	motor	NOUN
bptjm-29	86	26	neurons	neuron	NOUN
bptjm-29	86	27	.	.	PUNCT
bptjm-29	87	1	therefore	therefore	ADV
bptjm-29	87	2	,	,	PUNCT
bptjm-29	87	3	increasing	increase	VERB
bptjm-29	87	4	the	the	DET
bptjm-29	87	5	concentration	concentration	NOUN
bptjm-29	87	6	of	of	ADP
bptjm-29	87	7	glutamate	glutamate	ADJ
bptjm-29	87	8	transporters	transporter	NOUN
bptjm-29	87	9	would	would	AUX
bptjm-29	87	10	decrease	decrease	VERB
bptjm-29	87	11	the	the	DET
bptjm-29	87	12	synaptic	synaptic	ADJ
bptjm-29	87	13	glutamate	glutamate	NOUN
bptjm-29	87	14	concentration	concentration	NOUN
bptjm-29	87	15	and	and	CCONJ
bptjm-29	87	16	reduce	reduce	VERB
bptjm-29	87	17	excitotoxicity	excitotoxicity	NOUN
bptjm-29	87	18	levels	level	NOUN
bptjm-29	87	19	to	to	PART
bptjm-29	87	20	help	help	VERB
bptjm-29	87	21	prevent	prevent	VERB
bptjm-29	87	22	degeneration13	degeneration13	NOUN
bptjm-29	87	23	.	.	PUNCT
bptjm-29	88	1	2.3	2.3	NUM
bptjm-29	88	2	.	.	PUNCT
bptjm-29	88	3	neuroin	neuroin	PROPN
bptjm-29	88	4	�	�	PROPN
bptjm-29	88	5	ammation	ammation	NOUN
bptjm-29	88	6	and	and	CCONJ
bptjm-29	88	7	glial	glial	ADJ
bptjm-29	88	8	cells	cell	NOUN
bptjm-29	88	9	neuroin	neuroin	NOUN
bptjm-29	88	10	�	�	PROPN
bptjm-29	88	11	ammation	ammation	NOUN
bptjm-29	88	12	is	be	AUX
bptjm-29	88	13	an	an	DET
bptjm-29	88	14	immune	immune	ADJ
bptjm-29	88	15	response	response	NOUN
bptjm-29	88	16	in	in	ADP
bptjm-29	88	17	the	the	DET
bptjm-29	88	18	cns	cns	NOUN
bptjm-29	88	19	to	to	ADP
bptjm-29	88	20	neuronal	neuronal	ADJ
bptjm-29	88	21	damage	damage	NOUN
bptjm-29	88	22	and	and	CCONJ
bptjm-29	88	23	plays	play	VERB
bptjm-29	88	24	an	an	DET
bptjm-29	88	25	important	important	ADJ
bptjm-29	88	26	role	role	NOUN
bptjm-29	88	27	in	in	ADP
bptjm-29	88	28	the	the	DET
bptjm-29	88	29	pathogenesis	pathogenesis	NOUN
bptjm-29	88	30	of	of	ADP
bptjm-29	88	31	als	al	NOUN
bptjm-29	88	32	.	.	PUNCT
bptjm-29	89	1	an	an	DET
bptjm-29	89	2	immune	immune	ADJ
bptjm-29	89	3	response	response	NOUN
bptjm-29	89	4	is	be	AUX
bptjm-29	89	5	the	the	DET
bptjm-29	89	6	body	body	NOUN
bptjm-29	89	7	’s	’s	PART
bptjm-29	89	8	way	way	NOUN
bptjm-29	89	9	of	of	ADP
bptjm-29	89	10	�	�	NOUN
bptjm-29	89	11	ghting	ghte	VERB
bptjm-29	89	12	foreign	foreign	ADJ
bptjm-29	89	13	substances	substance	NOUN
bptjm-29	89	14	to	to	PART
bptjm-29	89	15	heal	heal	VERB
bptjm-29	89	16	damage	damage	NOUN
bptjm-29	89	17	,	,	PUNCT
bptjm-29	89	18	but	but	CCONJ
bptjm-29	89	19	this	this	PRON
bptjm-29	89	20	can	can	AUX
bptjm-29	89	21	become	become	VERB
bptjm-29	89	22	harmful	harmful	ADJ
bptjm-29	89	23	when	when	SCONJ
bptjm-29	89	24	accompanying	accompany	VERB
bptjm-29	89	25	a	a	DET
bptjm-29	89	26	disease20	disease20	NOUN
bptjm-29	89	27	.	.	PUNCT
bptjm-29	90	1	neuroin	neuroin	PROPN
bptjm-29	90	2	�	�	PROPN
bptjm-29	90	3	ammation	ammation	NOUN
bptjm-29	90	4	is	be	AUX
bptjm-29	90	5	characterized	characterize	VERB
bptjm-29	90	6	by	by	ADP
bptjm-29	90	7	overactivated	overactivated	ADJ
bptjm-29	90	8	microglia	microglia	NOUN
bptjm-29	90	9	,	,	PUNCT
bptjm-29	90	10	reactive	reactive	ADJ
bptjm-29	90	11	astrocytes	astrocyte	NOUN
bptjm-29	90	12	,	,	PUNCT
bptjm-29	90	13	and	and	CCONJ
bptjm-29	90	14	in	in	ADP
bptjm-29	90	15	�	�	PROPN
bptjm-29	90	16	ltrating	ltrating	NOUN
bptjm-29	90	17	immune	immune	ADJ
bptjm-29	90	18	cells	cell	NOUN
bptjm-29	90	19	such	such	ADJ
bptjm-29	90	20	as	as	ADP
bptjm-29	90	21	lymphocytes	lymphocyte	NOUN
bptjm-29	90	22	into	into	ADP
bptjm-29	90	23	the	the	DET
bptjm-29	90	24	site	site	NOUN
bptjm-29	90	25	of	of	ADP
bptjm-29	90	26	neuronal	neuronal	ADJ
bptjm-29	90	27	injury9	injury9	NOUN
bptjm-29	90	28	.	.	PUNCT
bptjm-29	91	1	as	as	ADP
bptjm-29	91	2	the	the	DET
bptjm-29	91	3	�	�	PROPN
bptjm-29	91	4	rst	rst	ADJ
bptjm-29	91	5	line	line	NOUN
bptjm-29	91	6	of	of	ADP
bptjm-29	91	7	defense	defense	NOUN
bptjm-29	91	8	within	within	ADP
bptjm-29	91	9	the	the	DET
bptjm-29	91	10	cns	cns	NOUN
bptjm-29	91	11	,	,	PUNCT
bptjm-29	91	12	microglia	microglia	NOUN
bptjm-29	91	13	are	be	AUX
bptjm-29	91	14	activated	activate	VERB
bptjm-29	91	15	and	and	CCONJ
bptjm-29	91	16	respond	respond	VERB
bptjm-29	91	17	to	to	ADP
bptjm-29	91	18	signals	signal	NOUN
bptjm-29	91	19	released	release	VERB
bptjm-29	91	20	by	by	ADP
bptjm-29	91	21	damaged	damaged	ADJ
bptjm-29	91	22	cells	cell	NOUN
bptjm-29	91	23	,	,	PUNCT
bptjm-29	91	24	more	more	ADJ
bptjm-29	91	25	speci	speci	ADJ
bptjm-29	91	26	�	�	PROPN
bptjm-29	91	27	cally	cally	ADV
bptjm-29	91	28	berkeley	berkeley	PROPN
bptjm-29	91	29	pharma	pharma	PROPN
bptjm-29	91	30	tech	tech	NOUN
bptjm-29	91	31	journal	journal	NOUN
bptjm-29	91	32	of	of	ADP
bptjm-29	91	33	medicine	medicine	NOUN
bptjm-29	91	34	|	|	ADV
bptjm-29	91	35	75	75	NUM
bptjm-29	91	36	https://www.zotero.org/google-docs/?bi37br	https://www.zotero.org/google-docs/?bi37br	PROPN
bptjm-29	91	37	https://www.zotero.org/google-docs/?ua3ebt	https://www.zotero.org/google-docs/?ua3ebt	PROPN
bptjm-29	92	1	https://www.zotero.org/google-docs/?vjlwju	https://www.zotero.org/google-docs/?vjlwju	PROPN
bptjm-29	92	2	https://www.zotero.org/google-docs/?2xfvqn	https://www.zotero.org/google-docs/?2xfvqn	PROPN
bptjm-29	93	1	https://www.zotero.org/google-docs/?i63i3p	https://www.zotero.org/google-docs/?i63i3p	PROPN
bptjm-29	93	2	https://www.zotero.org/google-docs/?zyqh6h	https://www.zotero.org/google-docs/?zyqh6h	INTJ
bptjm-29	93	3	https://www.zotero.org/google-docs/?i63i3p	https://www.zotero.org/google-docs/?i63i3p	PROPN
bptjm-29	93	4	https://www.zotero.org/google-docs/?knvyc7	https://www.zotero.org/google-docs/?knvyc7	AUX
bptjm-29	93	5	https://www.zotero.org/google-docs/?p46f10	https://www.zotero.org/google-docs/?p46f10	VERB
bptjm-29	93	6	injured	injure	VERB
bptjm-29	93	7	motor	motor	NOUN
bptjm-29	93	8	neurons21	neurons21	NOUN
bptjm-29	93	9	.	.	PUNCT
bptjm-29	94	1	glial	glial	ADJ
bptjm-29	94	2	cells	cell	NOUN
bptjm-29	94	3	refer	refer	VERB
bptjm-29	94	4	to	to	ADP
bptjm-29	94	5	the	the	DET
bptjm-29	94	6	cells	cell	NOUN
bptjm-29	94	7	present	present	ADJ
bptjm-29	94	8	in	in	ADP
bptjm-29	94	9	large	large	ADJ
bptjm-29	94	10	quantities	quantity	NOUN
bptjm-29	94	11	in	in	ADP
bptjm-29	94	12	the	the	DET
bptjm-29	94	13	cns	cns	NOUN
bptjm-29	94	14	and	and	CCONJ
bptjm-29	94	15	function	function	NOUN
bptjm-29	94	16	as	as	ADP
bptjm-29	94	17	mediators	mediator	NOUN
bptjm-29	94	18	of	of	ADP
bptjm-29	94	19	neuronal	neuronal	ADJ
bptjm-29	94	20	activity	activity	NOUN
bptjm-29	94	21	by	by	ADP
bptjm-29	94	22	surrounding	surround	VERB
bptjm-29	94	23	and	and	CCONJ
bptjm-29	94	24	separating	separate	VERB
bptjm-29	94	25	neurons	neuron	NOUN
bptjm-29	94	26	;	;	PUNCT
bptjm-29	94	27	they	they	PRON
bptjm-29	94	28	can	can	AUX
bptjm-29	94	29	also	also	ADV
bptjm-29	94	30	play	play	VERB
bptjm-29	94	31	a	a	DET
bptjm-29	94	32	part	part	NOUN
bptjm-29	94	33	in	in	ADP
bptjm-29	94	34	regenerating	regenerate	VERB
bptjm-29	94	35	damaged	damage	VERB
bptjm-29	94	36	neurons22	neurons22	NOUN
bptjm-29	94	37	.	.	PUNCT
bptjm-29	95	1	astrocytes	astrocyte	NOUN
bptjm-29	95	2	are	be	AUX
bptjm-29	95	3	a	a	DET
bptjm-29	95	4	type	type	NOUN
bptjm-29	95	5	of	of	ADP
bptjm-29	95	6	glial	glial	ADJ
bptjm-29	95	7	cells	cell	NOUN
bptjm-29	95	8	that	that	PRON
bptjm-29	95	9	are	be	AUX
bptjm-29	95	10	closely	closely	ADV
bptjm-29	95	11	associated	associate	VERB
bptjm-29	95	12	with	with	ADP
bptjm-29	95	13	motor	motor	NOUN
bptjm-29	95	14	neurons	neuron	NOUN
bptjm-29	95	15	.	.	PUNCT
bptjm-29	96	1	however	however	ADV
bptjm-29	96	2	,	,	PUNCT
bptjm-29	96	3	when	when	SCONJ
bptjm-29	96	4	the	the	DET
bptjm-29	96	5	damage	damage	NOUN
bptjm-29	96	6	becomes	become	VERB
bptjm-29	96	7	worse	bad	ADJ
bptjm-29	96	8	,	,	PUNCT
bptjm-29	96	9	astrocytes	astrocyte	NOUN
bptjm-29	96	10	and	and	CCONJ
bptjm-29	96	11	motor	motor	NOUN
bptjm-29	96	12	neurons	neuron	NOUN
bptjm-29	96	13	release	release	NOUN
bptjm-29	96	14	mutated	mutate	VERB
bptjm-29	96	15	sod1	sod1	ADJ
bptjm-29	96	16	proteins	protein	NOUN
bptjm-29	96	17	,	,	PUNCT
bptjm-29	96	18	which	which	PRON
bptjm-29	96	19	activate	activate	VERB
bptjm-29	96	20	pro	pro	ADJ
bptjm-29	96	21	-	-	ADJ
bptjm-29	96	22	in	in	ADP
bptjm-29	96	23	�	�	NOUN
bptjm-29	96	24	ammatory	ammatory	NOUN
bptjm-29	96	25	microglia	microglia	NOUN
bptjm-29	96	26	.	.	PUNCT
bptjm-29	97	1	there	there	PRON
bptjm-29	97	2	are	be	VERB
bptjm-29	97	3	two	two	NUM
bptjm-29	97	4	kinds	kind	NOUN
bptjm-29	97	5	of	of	ADP
bptjm-29	97	6	microglia	microglia	NOUN
bptjm-29	97	7	:	:	PUNCT
bptjm-29	97	8	m1	m1	NOUN
bptjm-29	97	9	type	type	NOUN
bptjm-29	97	10	microglia	microglia	NOUN
bptjm-29	97	11	and	and	CCONJ
bptjm-29	97	12	m2	m2	PROPN
bptjm-29	97	13	type	type	NOUN
bptjm-29	97	14	microglia	microglia	NOUN
bptjm-29	97	15	.	.	PUNCT
bptjm-29	98	1	m1	m1	NOUN
bptjm-29	98	2	microglia	microglia	NOUN
bptjm-29	98	3	are	be	AUX
bptjm-29	98	4	proin	proin	NOUN
bptjm-29	98	5	�	�	NOUN
bptjm-29	98	6	ammatory	ammatory	NOUN
bptjm-29	98	7	and	and	CCONJ
bptjm-29	98	8	secrete	secrete	NOUN
bptjm-29	98	9	ros	ros	PROPN
bptjm-29	98	10	and	and	CCONJ
bptjm-29	98	11	other	other	ADJ
bptjm-29	98	12	neurotoxic	neurotoxic	ADJ
bptjm-29	98	13	molecules	molecule	NOUN
bptjm-29	98	14	,	,	PUNCT
bptjm-29	98	15	which	which	PRON
bptjm-29	98	16	contribute	contribute	VERB
bptjm-29	98	17	to	to	ADP
bptjm-29	98	18	neuronal	neuronal	ADJ
bptjm-29	98	19	death9	death9	NOUN
bptjm-29	98	20	.	.	PUNCT
bptjm-29	99	1	by	by	ADP
bptjm-29	99	2	contrast	contrast	NOUN
bptjm-29	99	3	,	,	PUNCT
bptjm-29	99	4	m2	m2	PROPN
bptjm-29	99	5	microglia	microglia	PROPN
bptjm-29	99	6	are	be	AUX
bptjm-29	99	7	anti	anti	ADJ
bptjm-29	99	8	-	-	ADJ
bptjm-29	99	9	in	in	ADP
bptjm-29	99	10	�	�	NOUN
bptjm-29	99	11	ammatory	ammatory	NOUN
bptjm-29	99	12	and	and	CCONJ
bptjm-29	99	13	secrete	secrete	NOUN
bptjm-29	99	14	neurotrophic	neurotrophic	ADJ
bptjm-29	99	15	factors	factor	NOUN
bptjm-29	99	16	—	—	PUNCT
bptjm-29	99	17	molecules	molecule	NOUN
bptjm-29	99	18	that	that	PRON
bptjm-29	99	19	enable	enable	VERB
bptjm-29	99	20	neurons	neuron	NOUN
bptjm-29	99	21	to	to	PART
bptjm-29	99	22	maintain	maintain	VERB
bptjm-29	99	23	connections	connection	NOUN
bptjm-29	99	24	with	with	ADP
bptjm-29	99	25	other	other	ADJ
bptjm-29	99	26	neurons23	neurons23	NOUN
bptjm-29	99	27	.	.	PUNCT
bptjm-29	100	1	during	during	ADP
bptjm-29	100	2	the	the	DET
bptjm-29	100	3	early	early	ADJ
bptjm-29	100	4	stage	stage	NOUN
bptjm-29	100	5	of	of	ADP
bptjm-29	100	6	the	the	DET
bptjm-29	100	7	disease	disease	NOUN
bptjm-29	100	8	,	,	PUNCT
bptjm-29	100	9	microglia	microglia	NOUN
bptjm-29	100	10	with	with	ADP
bptjm-29	100	11	an	an	DET
bptjm-29	100	12	m2	m2	PROPN
bptjm-29	100	13	phenotype	phenotype	NOUN
bptjm-29	100	14	are	be	AUX
bptjm-29	100	15	present24	present24	ADJ
bptjm-29	100	16	.	.	PUNCT
bptjm-29	101	1	as	as	SCONJ
bptjm-29	101	2	the	the	DET
bptjm-29	101	3	disease	disease	NOUN
bptjm-29	101	4	progresses	progress	VERB
bptjm-29	101	5	,	,	PUNCT
bptjm-29	101	6	however	however	ADV
bptjm-29	101	7	,	,	PUNCT
bptjm-29	101	8	astrocytes	astrocyte	NOUN
bptjm-29	101	9	and	and	CCONJ
bptjm-29	101	10	motor	motor	NOUN
bptjm-29	101	11	neurons	neuron	NOUN
bptjm-29	101	12	activate	activate	VERB
bptjm-29	101	13	microglia	microglia	NOUN
bptjm-29	101	14	that	that	SCONJ
bptjm-29	101	15	present	present	ADJ
bptjm-29	101	16	with	with	ADP
bptjm-29	101	17	an	an	DET
bptjm-29	101	18	m1	m1	PROPN
bptjm-29	101	19	phenotype9	phenotype9	NOUN
bptjm-29	101	20	.	.	PUNCT
bptjm-29	102	1	these	these	DET
bptjm-29	102	2	m1	m1	PROPN
bptjm-29	102	3	microglia	microglia	NOUN
bptjm-29	102	4	release	release	NOUN
bptjm-29	102	5	ros	ros	PROPN
bptjm-29	102	6	and	and	CCONJ
bptjm-29	102	7	other	other	ADJ
bptjm-29	102	8	neurotoxic	neurotoxic	ADJ
bptjm-29	102	9	molecules	molecule	NOUN
bptjm-29	102	10	that	that	PRON
bptjm-29	102	11	contribute	contribute	VERB
bptjm-29	102	12	to	to	ADP
bptjm-29	102	13	neuronal	neuronal	ADJ
bptjm-29	102	14	degeneration	degeneration	NOUN
bptjm-29	102	15	.	.	PUNCT
bptjm-29	103	1	additionally	additionally	ADV
bptjm-29	103	2	,	,	PUNCT
bptjm-29	103	3	astrocytes	astrocyte	NOUN
bptjm-29	103	4	that	that	PRON
bptjm-29	103	5	are	be	AUX
bptjm-29	103	6	supposed	suppose	VERB
bptjm-29	103	7	to	to	PART
bptjm-29	103	8	support	support	VERB
bptjm-29	103	9	neurons	neuron	NOUN
bptjm-29	103	10	by	by	ADP
bptjm-29	103	11	using	use	VERB
bptjm-29	103	12	glutamate	glutamate	ADJ
bptjm-29	103	13	receptors	receptor	NOUN
bptjm-29	103	14	to	to	PART
bptjm-29	103	15	maintain	maintain	VERB
bptjm-29	103	16	low	low	ADJ
bptjm-29	103	17	synaptic	synaptic	ADJ
bptjm-29	103	18	glutamate	glutamate	NOUN
bptjm-29	103	19	levels	level	NOUN
bptjm-29	103	20	present	present	VERB
bptjm-29	103	21	di	di	NOUN
bptjm-29	103	22	�	�	PROPN
bptjm-29	103	23	erently	erently	ADV
bptjm-29	103	24	in	in	ADP
bptjm-29	103	25	als	als	NOUN
bptjm-29	103	26	patients	patient	NOUN
bptjm-29	103	27	who	who	PRON
bptjm-29	103	28	have	have	VERB
bptjm-29	103	29	astrocytes	astrocyte	NOUN
bptjm-29	103	30	with	with	ADP
bptjm-29	103	31	the	the	DET
bptjm-29	103	32	mutant	mutant	ADJ
bptjm-29	103	33	sod1	sod1	ADJ
bptjm-29	103	34	gene	gene	NOUN
bptjm-29	103	35	,	,	PUNCT
bptjm-29	103	36	which	which	PRON
bptjm-29	103	37	instead	instead	ADV
bptjm-29	103	38	induces	induce	VERB
bptjm-29	103	39	motor	motor	PROPN
bptjm-29	103	40	neuron	neuron	PROPN
bptjm-29	103	41	degeneration	degeneration	NOUN
bptjm-29	103	42	.	.	PUNCT
bptjm-29	104	1	they	they	PRON
bptjm-29	104	2	downregulate	downregulate	VERB
bptjm-29	104	3	the	the	DET
bptjm-29	104	4	glutamate	glutamate	ADJ
bptjm-29	104	5	transporters	transporter	NOUN
bptjm-29	104	6	,	,	PUNCT
bptjm-29	104	7	which	which	PRON
bptjm-29	104	8	in	in	ADP
bptjm-29	104	9	turn	turn	NOUN
bptjm-29	104	10	limit	limit	VERB
bptjm-29	104	11	the	the	DET
bptjm-29	104	12	amount	amount	NOUN
bptjm-29	104	13	of	of	ADP
bptjm-29	104	14	glutamate	glutamate	NOUN
bptjm-29	104	15	to	to	PART
bptjm-29	104	16	be	be	AUX
bptjm-29	104	17	uptaken	uptaken	VERB
bptjm-29	104	18	by	by	ADP
bptjm-29	104	19	the	the	DET
bptjm-29	104	20	receptors	receptor	NOUN
bptjm-29	104	21	out	out	ADP
bptjm-29	104	22	of	of	ADP
bptjm-29	104	23	the	the	DET
bptjm-29	104	24	synaptic	synaptic	ADJ
bptjm-29	104	25	cleft9	cleft9	NOUN
bptjm-29	104	26	.	.	PUNCT
bptjm-29	105	1	they	they	PRON
bptjm-29	105	2	also	also	ADV
bptjm-29	105	3	secrete	secrete	VERB
bptjm-29	105	4	in	in	ADP
bptjm-29	105	5	�	�	NOUN
bptjm-29	105	6	ammatory	ammatory	NOUN
bptjm-29	105	7	molecules	molecule	NOUN
bptjm-29	105	8	,	,	PUNCT
bptjm-29	105	9	and	and	CCONJ
bptjm-29	105	10	this	this	PRON
bptjm-29	105	11	in	in	ADP
bptjm-29	105	12	�	�	NOUN
bptjm-29	105	13	ammatory	ammatory	NOUN
bptjm-29	105	14	response	response	NOUN
bptjm-29	105	15	further	far	ADV
bptjm-29	105	16	contributes	contribute	VERB
bptjm-29	105	17	to	to	ADP
bptjm-29	105	18	the	the	DET
bptjm-29	105	19	alteration	alteration	NOUN
bptjm-29	105	20	and	and	CCONJ
bptjm-29	105	21	degeneration	degeneration	NOUN
bptjm-29	105	22	of	of	ADP
bptjm-29	105	23	motor	motor	NOUN
bptjm-29	105	24	neurons16	neurons16	PROPN
bptjm-29	105	25	.	.	PUNCT
bptjm-29	106	1	while	while	SCONJ
bptjm-29	106	2	neuroin	neuroin	NOUN
bptjm-29	106	3	�	�	PROPN
bptjm-29	106	4	ammation	ammation	NOUN
bptjm-29	106	5	is	be	AUX
bptjm-29	106	6	not	not	PART
bptjm-29	106	7	the	the	DET
bptjm-29	106	8	initial	initial	ADJ
bptjm-29	106	9	cause	cause	NOUN
bptjm-29	106	10	as	as	ADP
bptjm-29	106	11	to	to	ADP
bptjm-29	106	12	why	why	SCONJ
bptjm-29	106	13	motor	motor	NOUN
bptjm-29	106	14	neurons	neuron	NOUN
bptjm-29	106	15	degenerate	degenerate	VERB
bptjm-29	106	16	,	,	PUNCT
bptjm-29	106	17	it	it	PRON
bptjm-29	106	18	is	be	AUX
bptjm-29	106	19	a	a	DET
bptjm-29	106	20	response	response	NOUN
bptjm-29	106	21	to	to	ADP
bptjm-29	106	22	the	the	DET
bptjm-29	106	23	damaged	damage	VERB
bptjm-29	106	24	neurons	neuron	NOUN
bptjm-29	106	25	that	that	PRON
bptjm-29	106	26	further	far	ADV
bptjm-29	106	27	exacerbates	exacerbate	VERB
bptjm-29	106	28	degeneration20	degeneration20	NOUN
bptjm-29	106	29	.	.	PUNCT
bptjm-29	107	1	reducing	reduce	VERB
bptjm-29	107	2	the	the	PRON
bptjm-29	107	3	in	in	ADP
bptjm-29	107	4	�	�	NOUN
bptjm-29	107	5	ammatory	ammatory	NOUN
bptjm-29	107	6	e	e	NOUN
bptjm-29	107	7	�	�	NOUN
bptjm-29	107	8	ects	ect	NOUN
bptjm-29	107	9	caused	cause	VERB
bptjm-29	107	10	by	by	ADP
bptjm-29	107	11	overactivated	overactivate	VERB
bptjm-29	107	12	microglia	microglia	ADJ
bptjm-29	107	13	and	and	CCONJ
bptjm-29	107	14	reactive	reactive	ADJ
bptjm-29	107	15	astrocytes	astrocyte	NOUN
bptjm-29	107	16	could	could	AUX
bptjm-29	107	17	potentially	potentially	ADV
bptjm-29	107	18	be	be	AUX
bptjm-29	107	19	used	use	VERB
bptjm-29	107	20	to	to	PART
bptjm-29	107	21	reduce	reduce	VERB
bptjm-29	107	22	neuroin	neuroin	NOUN
bptjm-29	107	23	�	�	PROPN
bptjm-29	107	24	ammation	ammation	NOUN
bptjm-29	107	25	and	and	CCONJ
bptjm-29	107	26	slow	slow	ADJ
bptjm-29	107	27	neuronal	neuronal	ADJ
bptjm-29	107	28	degeneration	degeneration	NOUN
bptjm-29	107	29	.	.	PUNCT
bptjm-29	108	1	2.4	2.4	NUM
bptjm-29	108	2	.	.	PUNCT
bptjm-29	109	1	sod1	sod1	ADJ
bptjm-29	109	2	and	and	CCONJ
bptjm-29	109	3	oxidative	oxidative	ADJ
bptjm-29	109	4	stress	stress	NOUN
bptjm-29	109	5	oxidative	oxidative	ADJ
bptjm-29	109	6	stress	stress	NOUN
bptjm-29	109	7	is	be	AUX
bptjm-29	109	8	a	a	DET
bptjm-29	109	9	cellular	cellular	ADJ
bptjm-29	109	10	state	state	NOUN
bptjm-29	109	11	motor	motor	NOUN
bptjm-29	109	12	neurons	neuron	NOUN
bptjm-29	109	13	undergo	undergo	VERB
bptjm-29	109	14	that	that	SCONJ
bptjm-29	109	15	progresses	progress	NOUN
bptjm-29	109	16	and	and	CCONJ
bptjm-29	109	17	contributes	contribute	VERB
bptjm-29	109	18	to	to	PART
bptjm-29	109	19	als	als	VERB
bptjm-29	109	20	pathogenesis	pathogenesis	NOUN
bptjm-29	109	21	.	.	PUNCT
bptjm-29	110	1	als	als	NOUN
bptjm-29	110	2	patients	patient	NOUN
bptjm-29	110	3	have	have	AUX
bptjm-29	110	4	been	be	AUX
bptjm-29	110	5	shown	show	VERB
bptjm-29	110	6	to	to	ADP
bptjm-29	110	7	berkeley	berkeley	PROPN
bptjm-29	110	8	pharma	pharma	PROPN
bptjm-29	110	9	tech	tech	NOUN
bptjm-29	110	10	journal	journal	NOUN
bptjm-29	110	11	of	of	ADP
bptjm-29	110	12	medicine	medicine	NOUN
bptjm-29	110	13	|	|	ADV
bptjm-29	110	14	76	76	NUM
bptjm-29	110	15	https://www.zotero.org/google-docs/?ajduxz	https://www.zotero.org/google-docs/?ajduxz	NOUN
bptjm-29	110	16	https://www.zotero.org/google-docs/?x8u5uf	https://www.zotero.org/google-docs/?x8u5uf	PROPN
bptjm-29	110	17	https://www.zotero.org/google-docs/?3iih5k	https://www.zotero.org/google-docs/?3iih5k	PROPN
bptjm-29	110	18	https://www.zotero.org/google-docs/?wfrcoo	https://www.zotero.org/google-docs/?wfrcoo	PROPN
bptjm-29	110	19	https://www.zotero.org/google-docs/?ylvly8	https://www.zotero.org/google-docs/?ylvly8	PROPN
bptjm-29	110	20	https://www.zotero.org/google-docs/?pgk8rm	https://www.zotero.org/google-docs/?pgk8rm	PROPN
bptjm-29	111	1	https://www.zotero.org/google-docs/?fyu7me	https://www.zotero.org/google-docs/?fyu7me	PROPN
bptjm-29	111	2	https://www.zotero.org/google-docs/?oxcbfp	https://www.zotero.org/google-docs/?oxcbfp	PROPN
bptjm-29	111	3	https://www.zotero.org/google-docs/?95hnmr	https://www.zotero.org/google-docs/?95hnmr	PROPN
bptjm-29	111	4	have	have	VERB
bptjm-29	111	5	an	an	DET
bptjm-29	111	6	increased	increase	VERB
bptjm-29	111	7	level	level	NOUN
bptjm-29	111	8	of	of	ADP
bptjm-29	111	9	oxidation	oxidation	NOUN
bptjm-29	111	10	,	,	PUNCT
bptjm-29	111	11	meaning	mean	VERB
bptjm-29	111	12	they	they	PRON
bptjm-29	111	13	are	be	AUX
bptjm-29	111	14	in	in	ADP
bptjm-29	111	15	oxidative	oxidative	ADJ
bptjm-29	111	16	stress	stress	NOUN
bptjm-29	111	17	.	.	PUNCT
bptjm-29	112	1	oxidative	oxidative	ADJ
bptjm-29	112	2	stress	stress	NOUN
bptjm-29	112	3	occurs	occur	VERB
bptjm-29	112	4	when	when	SCONJ
bptjm-29	112	5	reactive	reactive	ADJ
bptjm-29	112	6	oxygen	oxygen	NOUN
bptjm-29	112	7	species	specie	NOUN
bptjm-29	112	8	(	(	PUNCT
bptjm-29	112	9	ros	ros	PROPN
bptjm-29	112	10	)	)	PUNCT
bptjm-29	112	11	accumulate	accumulate	NOUN
bptjm-29	112	12	within	within	ADP
bptjm-29	112	13	the	the	DET
bptjm-29	112	14	cell	cell	NOUN
bptjm-29	112	15	or	or	CCONJ
bptjm-29	112	16	are	be	AUX
bptjm-29	112	17	being	be	AUX
bptjm-29	112	18	produced	produce	VERB
bptjm-29	112	19	at	at	ADP
bptjm-29	112	20	a	a	DET
bptjm-29	112	21	greater	great	ADJ
bptjm-29	112	22	rate	rate	NOUN
bptjm-29	112	23	than	than	SCONJ
bptjm-29	112	24	they	they	PRON
bptjm-29	112	25	are	be	AUX
bptjm-29	112	26	removed	remove	VERB
bptjm-29	112	27	,	,	PUNCT
bptjm-29	112	28	meaning	mean	VERB
bptjm-29	112	29	the	the	DET
bptjm-29	112	30	cell	cell	NOUN
bptjm-29	112	31	is	be	AUX
bptjm-29	112	32	unable	unable	ADJ
bptjm-29	112	33	to	to	PART
bptjm-29	112	34	repair	repair	VERB
bptjm-29	112	35	the	the	DET
bptjm-29	112	36	stress25	stress25	NOUN
bptjm-29	112	37	.	.	PUNCT
bptjm-29	113	1	this	this	PRON
bptjm-29	113	2	causes	cause	VERB
bptjm-29	113	3	permanent	permanent	ADJ
bptjm-29	113	4	damage	damage	NOUN
bptjm-29	113	5	to	to	ADP
bptjm-29	113	6	cell	cell	NOUN
bptjm-29	113	7	structures	structure	NOUN
bptjm-29	113	8	and	and	CCONJ
bptjm-29	113	9	macromolecules	macromolecule	NOUN
bptjm-29	113	10	.	.	PUNCT
bptjm-29	114	1	the	the	DET
bptjm-29	114	2	term	term	NOUN
bptjm-29	114	3	ros	ros	PROPN
bptjm-29	114	4	embodies	embody	VERB
bptjm-29	114	5	superoxide	superoxide	NOUN
bptjm-29	114	6	,	,	PUNCT
bptjm-29	114	7	ozone	ozone	NOUN
bptjm-29	114	8	,	,	PUNCT
bptjm-29	114	9	and	and	CCONJ
bptjm-29	114	10	all	all	DET
bptjm-29	114	11	other	other	ADJ
bptjm-29	114	12	reactive	reactive	ADJ
bptjm-29	114	13	species	specie	NOUN
bptjm-29	114	14	that	that	PRON
bptjm-29	114	15	contain	contain	VERB
bptjm-29	114	16	oxygen26	oxygen26	NOUN
bptjm-29	114	17	.	.	PUNCT
bptjm-29	115	1	sod1	sod1	PROPN
bptjm-29	115	2	is	be	AUX
bptjm-29	115	3	a	a	DET
bptjm-29	115	4	major	major	ADJ
bptjm-29	115	5	enzyme	enzyme	NOUN
bptjm-29	115	6	used	use	VERB
bptjm-29	115	7	to	to	PART
bptjm-29	115	8	prevent	prevent	VERB
bptjm-29	115	9	oxidative	oxidative	ADJ
bptjm-29	115	10	damage28	damage28	NOUN
bptjm-29	115	11	.	.	PUNCT
bptjm-29	116	1	most	most	ADJ
bptjm-29	116	2	neurodegenerative	neurodegenerative	ADJ
bptjm-29	116	3	diseases	disease	NOUN
bptjm-29	116	4	are	be	AUX
bptjm-29	116	5	characterized	characterize	VERB
bptjm-29	116	6	by	by	ADP
bptjm-29	116	7	the	the	DET
bptjm-29	116	8	cellular	cellular	ADJ
bptjm-29	116	9	accumulation	accumulation	NOUN
bptjm-29	116	10	of	of	ADP
bptjm-29	116	11	misfolded	misfolde	VERB
bptjm-29	116	12	proteins	protein	NOUN
bptjm-29	116	13	.	.	PUNCT
bptjm-29	117	1	in	in	ADP
bptjm-29	117	2	als	als	NOUN
bptjm-29	117	3	mutant	mutant	ADJ
bptjm-29	117	4	sod1	sod1	ADJ
bptjm-29	117	5	proteins	protein	NOUN
bptjm-29	117	6	aggregate	aggregate	VERB
bptjm-29	117	7	and	and	CCONJ
bptjm-29	117	8	alter	alter	VERB
bptjm-29	117	9	normal	normal	ADJ
bptjm-29	117	10	cell	cell	NOUN
bptjm-29	117	11	function	function	NOUN
bptjm-29	117	12	.	.	PUNCT
bptjm-29	118	1	the	the	DET
bptjm-29	118	2	original	original	ADJ
bptjm-29	118	3	function	function	NOUN
bptjm-29	118	4	of	of	ADP
bptjm-29	118	5	the	the	DET
bptjm-29	118	6	sod1	sod1	ADJ
bptjm-29	118	7	enzymes	enzyme	NOUN
bptjm-29	118	8	is	be	AUX
bptjm-29	118	9	to	to	PART
bptjm-29	118	10	reduce	reduce	VERB
bptjm-29	118	11	the	the	DET
bptjm-29	118	12	reactive	reactive	ADJ
bptjm-29	118	13	oxygen	oxygen	NOUN
bptjm-29	118	14	species	specie	NOUN
bptjm-29	118	15	(	(	PUNCT
bptjm-29	118	16	ros	ros	PROPN
bptjm-29	118	17	)	)	PUNCT
bptjm-29	118	18	released	release	VERB
bptjm-29	118	19	from	from	ADP
bptjm-29	118	20	the	the	DET
bptjm-29	118	21	mitochondria	mitochondria	NOUN
bptjm-29	118	22	.	.	PUNCT
bptjm-29	119	1	they	they	PRON
bptjm-29	119	2	do	do	VERB
bptjm-29	119	3	this	this	PRON
bptjm-29	119	4	by	by	ADP
bptjm-29	119	5	catalyzing	catalyze	VERB
bptjm-29	119	6	the	the	DET
bptjm-29	119	7	conversion	conversion	NOUN
bptjm-29	119	8	from	from	ADP
bptjm-29	119	9	superoxide	superoxide	NOUN
bptjm-29	119	10	into	into	ADP
bptjm-29	119	11	oxygen	oxygen	NOUN
bptjm-29	119	12	and	and	CCONJ
bptjm-29	119	13	hydrogen	hydrogen	NOUN
bptjm-29	119	14	peroxide	peroxide	NOUN
bptjm-29	119	15	.	.	PUNCT
bptjm-29	120	1	this	this	DET
bptjm-29	120	2	process	process	NOUN
bptjm-29	120	3	plays	play	VERB
bptjm-29	120	4	an	an	DET
bptjm-29	120	5	important	important	ADJ
bptjm-29	120	6	role	role	NOUN
bptjm-29	120	7	in	in	ADP
bptjm-29	120	8	the	the	DET
bptjm-29	120	9	antioxidant	antioxidant	ADJ
bptjm-29	120	10	defense	defense	NOUN
bptjm-29	120	11	of	of	ADP
bptjm-29	120	12	motor	motor	PROPN
bptjm-29	120	13	neurons16	neurons16	PROPN
bptjm-29	120	14	.	.	PUNCT
bptjm-29	121	1	however	however	ADV
bptjm-29	121	2	,	,	PUNCT
bptjm-29	121	3	in	in	ADP
bptjm-29	121	4	als	al	NOUN
bptjm-29	121	5	,	,	PUNCT
bptjm-29	121	6	the	the	DET
bptjm-29	121	7	mutant	mutant	ADJ
bptjm-29	121	8	sod1	sod1	ADJ
bptjm-29	121	9	enzymes	enzyme	NOUN
bptjm-29	121	10	no	no	ADV
bptjm-29	121	11	longer	long	ADV
bptjm-29	121	12	function	function	VERB
bptjm-29	121	13	as	as	ADP
bptjm-29	121	14	important	important	ADJ
bptjm-29	121	15	molecules	molecule	NOUN
bptjm-29	121	16	for	for	ADP
bptjm-29	121	17	antioxidant	antioxidant	ADJ
bptjm-29	121	18	activity	activity	NOUN
bptjm-29	121	19	,	,	PUNCT
bptjm-29	121	20	but	but	CCONJ
bptjm-29	121	21	instead	instead	ADV
bptjm-29	121	22	create	create	VERB
bptjm-29	121	23	oxidative	oxidative	ADJ
bptjm-29	121	24	stress	stress	NOUN
bptjm-29	121	25	.	.	PUNCT
bptjm-29	122	1	they	they	PRON
bptjm-29	122	2	convert	convert	VERB
bptjm-29	122	3	antioxidants	antioxidant	NOUN
bptjm-29	122	4	into	into	ADP
bptjm-29	122	5	superoxide	superoxide	NOUN
bptjm-29	122	6	by	by	ADP
bptjm-29	122	7	donating	donate	VERB
bptjm-29	122	8	electrons	electron	NOUN
bptjm-29	122	9	from	from	ADP
bptjm-29	122	10	antioxidants	antioxidant	NOUN
bptjm-29	122	11	to	to	ADP
bptjm-29	122	12	molecular	molecular	ADJ
bptjm-29	122	13	oxygen	oxygen	NOUN
bptjm-29	122	14	.	.	PUNCT
bptjm-29	123	1	in	in	ADP
bptjm-29	123	2	this	this	DET
bptjm-29	123	3	case	case	NOUN
bptjm-29	123	4	,	,	PUNCT
bptjm-29	123	5	oxidative	oxidative	ADJ
bptjm-29	123	6	stress	stress	NOUN
bptjm-29	123	7	is	be	AUX
bptjm-29	123	8	not	not	PART
bptjm-29	123	9	caused	cause	VERB
bptjm-29	123	10	by	by	ADP
bptjm-29	123	11	a	a	DET
bptjm-29	123	12	decrease	decrease	NOUN
bptjm-29	123	13	or	or	CCONJ
bptjm-29	123	14	loss	loss	NOUN
bptjm-29	123	15	in	in	ADP
bptjm-29	123	16	the	the	DET
bptjm-29	123	17	function	function	NOUN
bptjm-29	123	18	of	of	ADP
bptjm-29	123	19	sod1	sod1	NOUN
bptjm-29	123	20	but	but	CCONJ
bptjm-29	123	21	rather	rather	ADV
bptjm-29	123	22	a	a	DET
bptjm-29	123	23	new	new	ADJ
bptjm-29	123	24	toxic	toxic	ADJ
bptjm-29	123	25	function	function	NOUN
bptjm-29	123	26	of	of	ADP
bptjm-29	123	27	the	the	DET
bptjm-29	123	28	enzyme9	enzyme9	NOUN
bptjm-29	123	29	.	.	PUNCT
bptjm-29	124	1	not	not	PART
bptjm-29	124	2	only	only	ADV
bptjm-29	124	3	is	be	AUX
bptjm-29	124	4	oxidative	oxidative	ADJ
bptjm-29	124	5	stress	stress	NOUN
bptjm-29	124	6	linked	link	VERB
bptjm-29	124	7	to	to	ADP
bptjm-29	124	8	the	the	DET
bptjm-29	124	9	progression	progression	NOUN
bptjm-29	124	10	of	of	ADP
bptjm-29	124	11	als	al	NOUN
bptjm-29	124	12	,	,	PUNCT
bptjm-29	124	13	it	it	PRON
bptjm-29	124	14	also	also	ADV
bptjm-29	124	15	contributes	contribute	VERB
bptjm-29	124	16	to	to	ADP
bptjm-29	124	17	the	the	DET
bptjm-29	124	18	other	other	ADJ
bptjm-29	124	19	pathogenetic	pathogenetic	ADJ
bptjm-29	124	20	mechanisms	mechanism	NOUN
bptjm-29	124	21	as	as	ADV
bptjm-29	124	22	well	well	ADV
bptjm-29	124	23	.	.	PUNCT
bptjm-29	125	1	when	when	SCONJ
bptjm-29	125	2	mutant	mutant	ADJ
bptjm-29	125	3	sod1	sod1	ADJ
bptjm-29	125	4	enzymes	enzyme	NOUN
bptjm-29	125	5	are	be	AUX
bptjm-29	125	6	present	present	ADJ
bptjm-29	125	7	in	in	ADP
bptjm-29	125	8	the	the	DET
bptjm-29	125	9	mitochondria	mitochondria	NOUN
bptjm-29	125	10	,	,	PUNCT
bptjm-29	125	11	the	the	DET
bptjm-29	125	12	mitochondria	mitochondria	NOUN
bptjm-29	125	13	produces	produce	VERB
bptjm-29	125	14	an	an	DET
bptjm-29	125	15	abnormal	abnormal	ADJ
bptjm-29	125	16	amount	amount	NOUN
bptjm-29	125	17	of	of	ADP
bptjm-29	125	18	ros	ros	PROPN
bptjm-29	125	19	,	,	PUNCT
bptjm-29	125	20	which	which	PRON
bptjm-29	125	21	,	,	PUNCT
bptjm-29	125	22	in	in	ADP
bptjm-29	125	23	turn	turn	NOUN
bptjm-29	125	24	,	,	PUNCT
bptjm-29	125	25	exacerbates	exacerbate	VERB
bptjm-29	125	26	oxidative	oxidative	ADJ
bptjm-29	125	27	stress16	stress16	NOUN
bptjm-29	125	28	.	.	PUNCT
bptjm-29	126	1	furthermore	furthermore	ADV
bptjm-29	126	2	,	,	PUNCT
bptjm-29	126	3	this	this	PRON
bptjm-29	126	4	also	also	ADV
bptjm-29	126	5	determines	determine	VERB
bptjm-29	126	6	excitatory	excitatory	ADJ
bptjm-29	126	7	damage	damage	NOUN
bptjm-29	126	8	and	and	CCONJ
bptjm-29	126	9	therefore	therefore	ADV
bptjm-29	126	10	motor	motor	PROPN
bptjm-29	126	11	neuron	neuron	PROPN
bptjm-29	126	12	degeneration	degeneration	NOUN
bptjm-29	126	13	.	.	PUNCT
bptjm-29	127	1	berkeley	berkeley	PROPN
bptjm-29	127	2	pharma	pharma	PROPN
bptjm-29	127	3	tech	tech	PROPN
bptjm-29	127	4	journal	journal	NOUN
bptjm-29	127	5	of	of	ADP
bptjm-29	127	6	medicine	medicine	NOUN
bptjm-29	127	7	|	|	ADV
bptjm-29	127	8	77	77	NUM
bptjm-29	127	9	https://www.zotero.org/google-docs/?eimuju	https://www.zotero.org/google-docs/?eimuju	NOUN
bptjm-29	127	10	https://www.zotero.org/google-docs/?3w9fkd	https://www.zotero.org/google-docs/?3w9fkd	NOUN
bptjm-29	127	11	https://www.zotero.org/google-docs/?oiih9	https://www.zotero.org/google-docs/?oiih9	PROPN
bptjm-29	127	12	t	t	PROPN
bptjm-29	127	13	https://www.zotero.org/google-docs/?cqzxx2	https://www.zotero.org/google-docs/?cqzxx2	PROPN
bptjm-29	127	14	https://www.zotero.org/google-docs/?nlhgje	https://www.zotero.org/google-docs/?nlhgje	NOUN
bptjm-29	127	15	https://www.zotero.org/google-docs/?ytaeys	https://www.zotero.org/google-docs/?ytaey	NOUN
bptjm-29	127	16	figure	figure	VERB
bptjm-29	127	17	1	1	NUM
bptjm-29	127	18	.	.	PUNCT
bptjm-29	128	1	the	the	DET
bptjm-29	128	2	four	four	NUM
bptjm-29	128	3	pathogenetic	pathogenetic	ADJ
bptjm-29	128	4	mechanisms	mechanism	NOUN
bptjm-29	128	5	of	of	ADP
bptjm-29	128	6	als	al	NOUN
bptjm-29	128	7	:	:	PUNCT
bptjm-29	128	8	mitochondrial	mitochondrial	ADJ
bptjm-29	128	9	dysfunction	dysfunction	NOUN
bptjm-29	128	10	,	,	PUNCT
bptjm-29	128	11	glutamate	glutamate	VERB
bptjm-29	128	12	excitotoxicity	excitotoxicity	NOUN
bptjm-29	128	13	,	,	PUNCT
bptjm-29	128	14	inflammation	inflammation	NOUN
bptjm-29	128	15	,	,	PUNCT
bptjm-29	128	16	oxidative	oxidative	ADJ
bptjm-29	128	17	stress	stress	NOUN
bptjm-29	128	18	.	.	PUNCT
bptjm-29	129	1	3	3	X
bptjm-29	129	2	.	.	NOUN
bptjm-29	129	3	novel	novel	ADJ
bptjm-29	129	4	cell	cell	NOUN
bptjm-29	129	5	therapies	therapy	NOUN
bptjm-29	129	6	3.1	3.1	NUM
bptjm-29	129	7	.	.	PUNCT
bptjm-29	130	1	pharmacological	pharmacological	ADJ
bptjm-29	130	2	approaches	approach	NOUN
bptjm-29	130	3	pharmacological	pharmacological	ADJ
bptjm-29	130	4	therapies	therapy	NOUN
bptjm-29	130	5	for	for	ADP
bptjm-29	130	6	als	als	NOUN
bptjm-29	130	7	target	target	NOUN
bptjm-29	130	8	neurodegeneration	neurodegeneration	NOUN
bptjm-29	130	9	by	by	ADP
bptjm-29	130	10	stagnating	stagnate	VERB
bptjm-29	130	11	or	or	CCONJ
bptjm-29	130	12	impeding	impede	VERB
bptjm-29	130	13	the	the	DET
bptjm-29	130	14	death	death	NOUN
bptjm-29	130	15	of	of	ADP
bptjm-29	130	16	motor	motor	NOUN
bptjm-29	130	17	neurons	neuron	NOUN
bptjm-29	130	18	.	.	PUNCT
bptjm-29	131	1	riluzole	riluzole	PROPN
bptjm-29	131	2	is	be	AUX
bptjm-29	131	3	the	the	DET
bptjm-29	131	4	�	�	PROPN
bptjm-29	131	5	rst	rst	PROPN
bptjm-29	131	6	fda	fda	PROPN
bptjm-29	131	7	approved	approve	VERB
bptjm-29	131	8	drug	drug	NOUN
bptjm-29	131	9	for	for	ADP
bptjm-29	131	10	als	als	NOUN
bptjm-29	131	11	after	after	SCONJ
bptjm-29	131	12	it	it	PRON
bptjm-29	131	13	initially	initially	ADV
bptjm-29	131	14	proved	prove	VERB
bptjm-29	131	15	to	to	PART
bptjm-29	131	16	be	be	AUX
bptjm-29	131	17	successful	successful	ADJ
bptjm-29	131	18	in	in	ADP
bptjm-29	131	19	clinical	clinical	ADJ
bptjm-29	131	20	trials	trial	NOUN
bptjm-29	131	21	in	in	ADP
bptjm-29	131	22	the	the	DET
bptjm-29	131	23	1990s28	1990s28	NUM
bptjm-29	131	24	.	.	PUNCT
bptjm-29	132	1	common	common	ADJ
bptjm-29	132	2	brand	brand	NOUN
bptjm-29	132	3	names	name	NOUN
bptjm-29	132	4	of	of	ADP
bptjm-29	132	5	riluzole	riluzole	NOUN
bptjm-29	132	6	are	be	AUX
bptjm-29	132	7	exservan	exservan	ADJ
bptjm-29	132	8	,	,	PUNCT
bptjm-29	132	9	rilutek	rilutek	NOUN
bptjm-29	132	10	,	,	PUNCT
bptjm-29	132	11	and	and	CCONJ
bptjm-29	132	12	tiglutik	tiglutik	NOUN
bptjm-29	132	13	.	.	PUNCT
bptjm-29	133	1	since	since	SCONJ
bptjm-29	133	2	its	its	PRON
bptjm-29	133	3	successful	successful	ADJ
bptjm-29	133	4	administration	administration	NOUN
bptjm-29	133	5	,	,	PUNCT
bptjm-29	133	6	new	new	ADJ
bptjm-29	133	7	drugs	drug	NOUN
bptjm-29	133	8	including	include	VERB
bptjm-29	133	9	edaravone	edaravone	NOUN
bptjm-29	133	10	and	and	CCONJ
bptjm-29	133	11	amx0035	amx0035	NOUN
bptjm-29	133	12	have	have	AUX
bptjm-29	133	13	been	be	AUX
bptjm-29	133	14	studied	study	VERB
bptjm-29	133	15	to	to	PART
bptjm-29	133	16	evaluate	evaluate	VERB
bptjm-29	133	17	their	their	PRON
bptjm-29	133	18	e	e	NOUN
bptjm-29	133	19	�	�	NOUN
bptjm-29	133	20	cacy	cacy	NOUN
bptjm-29	133	21	against	against	ADP
bptjm-29	133	22	predecessors	predecessor	NOUN
bptjm-29	133	23	.	.	PUNCT
bptjm-29	134	1	riluzole	riluzole	NOUN
bptjm-29	134	2	functions	function	NOUN
bptjm-29	134	3	by	by	ADP
bptjm-29	134	4	protecting	protect	VERB
bptjm-29	134	5	motor	motor	NOUN
bptjm-29	134	6	neuron	neuron	NOUN
bptjm-29	134	7	cell	cell	NOUN
bptjm-29	134	8	lines	line	NOUN
bptjm-29	134	9	from	from	ADP
bptjm-29	134	10	glutamate	glutamate	ADJ
bptjm-29	134	11	stress	stress	NOUN
bptjm-29	134	12	.	.	PUNCT
bptjm-29	135	1	glutamate	glutamate	NOUN
bptjm-29	135	2	is	be	AUX
bptjm-29	135	3	an	an	DET
bptjm-29	135	4	essential	essential	ADJ
bptjm-29	135	5	neural	neural	ADJ
bptjm-29	135	6	excitatory	excitatory	NOUN
bptjm-29	135	7	neurotransmitter	neurotransmitter	NOUN
bptjm-29	135	8	which	which	PRON
bptjm-29	135	9	facilitates	facilitate	VERB
bptjm-29	135	10	proper	proper	ADJ
bptjm-29	135	11	signal	signal	NOUN
bptjm-29	135	12	propagation	propagation	NOUN
bptjm-29	135	13	throughout	throughout	ADP
bptjm-29	135	14	the	the	DET
bptjm-29	135	15	central	central	ADJ
bptjm-29	135	16	nervous	nervous	ADJ
bptjm-29	135	17	system29	system29	NOUN
bptjm-29	135	18	.	.	PUNCT
bptjm-29	136	1	imbalances	imbalance	NOUN
bptjm-29	136	2	in	in	ADP
bptjm-29	136	3	glutamate	glutamate	ADJ
bptjm-29	136	4	levels	level	NOUN
bptjm-29	136	5	can	can	AUX
bptjm-29	136	6	a	a	DET
bptjm-29	136	7	�	�	X
bptjm-29	136	8	ect	ect	ADJ
bptjm-29	136	9	nerve	nerve	NOUN
bptjm-29	136	10	health	health	NOUN
bptjm-29	136	11	and	and	CCONJ
bptjm-29	136	12	contribute	contribute	VERB
bptjm-29	136	13	to	to	ADP
bptjm-29	136	14	cell	cell	NOUN
bptjm-29	136	15	death	death	NOUN
bptjm-29	136	16	.	.	PUNCT
bptjm-29	137	1	like	like	ADP
bptjm-29	137	2	many	many	ADJ
bptjm-29	137	3	neurodegenerative	neurodegenerative	ADJ
bptjm-29	137	4	therapeutics	therapeutic	NOUN
bptjm-29	137	5	,	,	PUNCT
bptjm-29	137	6	riluzole	riluzole	NOUN
bptjm-29	137	7	prevents	prevent	VERB
bptjm-29	137	8	excitotoxicity	excitotoxicity	NOUN
bptjm-29	137	9	and	and	CCONJ
bptjm-29	137	10	slows	slow	VERB
bptjm-29	137	11	degeneration	degeneration	NOUN
bptjm-29	137	12	of	of	ADP
bptjm-29	137	13	motor	motor	NOUN
bptjm-29	137	14	neurons	neuron	NOUN
bptjm-29	137	15	.	.	PUNCT
bptjm-29	138	1	the	the	DET
bptjm-29	138	2	most	most	ADV
bptjm-29	138	3	prominent	prominent	ADJ
bptjm-29	138	4	clinical	clinical	ADJ
bptjm-29	138	5	trials	trial	NOUN
bptjm-29	138	6	involving	involve	VERB
bptjm-29	138	7	solely	solely	ADV
bptjm-29	138	8	riluzole	riluzole	NOUN
bptjm-29	138	9	as	as	ADP
bptjm-29	138	10	a	a	DET
bptjm-29	138	11	therapeutic	therapeutic	NOUN
bptjm-29	138	12	for	for	ADP
bptjm-29	138	13	als	al	NOUN
bptjm-29	138	14	are	be	AUX
bptjm-29	138	15	from	from	ADP
bptjm-29	138	16	the	the	DET
bptjm-29	138	17	late	late	ADJ
bptjm-29	138	18	20th	20th	ADJ
bptjm-29	138	19	century	century	NOUN
bptjm-29	138	20	where	where	SCONJ
bptjm-29	138	21	the	the	DET
bptjm-29	138	22	drug	drug	NOUN
bptjm-29	138	23	was	be	AUX
bptjm-29	138	24	initially	initially	ADV
bptjm-29	138	25	found	find	VERB
bptjm-29	138	26	to	to	PART
bptjm-29	138	27	be	be	AUX
bptjm-29	138	28	a	a	DET
bptjm-29	138	29	successful	successful	ADJ
bptjm-29	138	30	treatment	treatment	NOUN
bptjm-29	138	31	.	.	PUNCT
bptjm-29	139	1	in	in	ADP
bptjm-29	139	2	a	a	DET
bptjm-29	139	3	1994	1994	NUM
bptjm-29	139	4	clinical	clinical	ADJ
bptjm-29	139	5	trial	trial	NOUN
bptjm-29	139	6	,	,	PUNCT
bptjm-29	139	7	conducted	conduct	VERB
bptjm-29	139	8	before	before	ADP
bptjm-29	139	9	the	the	DET
bptjm-29	139	10	fda	fda	PROPN
bptjm-29	139	11	approval	approval	NOUN
bptjm-29	139	12	of	of	ADP
bptjm-29	139	13	riluzole	riluzole	NOUN
bptjm-29	139	14	in	in	ADP
bptjm-29	139	15	1995	1995	NUM
bptjm-29	139	16	,	,	PUNCT
bptjm-29	139	17	riluzole	riluzole	NOUN
bptjm-29	139	18	slowed	slow	VERB
bptjm-29	139	19	als	als	NOUN
bptjm-29	139	20	progression	progression	NOUN
bptjm-29	139	21	by	by	ADP
bptjm-29	139	22	inhibiting	inhibit	VERB
bptjm-29	139	23	berkeley	berkeley	PROPN
bptjm-29	139	24	pharma	pharma	PROPN
bptjm-29	139	25	tech	tech	NOUN
bptjm-29	139	26	journal	journal	NOUN
bptjm-29	139	27	of	of	ADP
bptjm-29	139	28	medicine	medicine	NOUN
bptjm-29	139	29	|	|	ADV
bptjm-29	139	30	78	78	NUM
bptjm-29	139	31	https://www.zotero.org/google-docs/?id0erx	https://www.zotero.org/google-docs/?id0erx	NOUN
bptjm-29	139	32	https://www.zotero.org/google-docs/?xmwe24	https://www.zotero.org/google-docs/?xmwe24	NOUN
bptjm-29	139	33	disease	disease	NOUN
bptjm-29	139	34	processes	process	NOUN
bptjm-29	139	35	in	in	ADP
bptjm-29	139	36	the	the	DET
bptjm-29	139	37	cns30	cns30	NOUN
bptjm-29	139	38	.	.	PUNCT
bptjm-29	140	1	factors	factor	NOUN
bptjm-29	140	2	including	include	VERB
bptjm-29	140	3	death	death	NOUN
bptjm-29	140	4	rate	rate	NOUN
bptjm-29	140	5	and	and	CCONJ
bptjm-29	140	6	deterioration	deterioration	NOUN
bptjm-29	140	7	of	of	ADP
bptjm-29	140	8	muscle	muscle	NOUN
bptjm-29	140	9	strength	strength	NOUN
bptjm-29	140	10	were	be	AUX
bptjm-29	140	11	higher	high	ADJ
bptjm-29	140	12	for	for	ADP
bptjm-29	140	13	the	the	DET
bptjm-29	140	14	placebo	placebo	NOUN
bptjm-29	140	15	group	group	NOUN
bptjm-29	140	16	than	than	ADP
bptjm-29	140	17	those	those	PRON
bptjm-29	140	18	treated	treat	VERB
bptjm-29	140	19	with	with	ADP
bptjm-29	140	20	riluzole	riluzole	NOUN
bptjm-29	140	21	in	in	ADP
bptjm-29	140	22	a	a	DET
bptjm-29	140	23	one	one	NUM
bptjm-29	140	24	year	year	NOUN
bptjm-29	140	25	period	period	NOUN
bptjm-29	140	26	.	.	PUNCT
bptjm-29	141	1	the	the	DET
bptjm-29	141	2	study	study	NOUN
bptjm-29	141	3	also	also	ADV
bptjm-29	141	4	noted	note	VERB
bptjm-29	141	5	that	that	SCONJ
bptjm-29	141	6	a	a	DET
bptjm-29	141	7	subsequent	subsequent	ADJ
bptjm-29	141	8	experiment	experiment	NOUN
bptjm-29	141	9	on	on	ADP
bptjm-29	141	10	dosage	dosage	NOUN
bptjm-29	141	11	should	should	AUX
bptjm-29	141	12	be	be	AUX
bptjm-29	141	13	conducted	conduct	VERB
bptjm-29	141	14	to	to	PART
bptjm-29	141	15	which	which	PRON
bptjm-29	141	16	researchers	researcher	NOUN
bptjm-29	141	17	in	in	ADP
bptjm-29	141	18	1996	1996	NUM
bptjm-29	141	19	tested	test	VERB
bptjm-29	141	20	the	the	DET
bptjm-29	141	21	impact	impact	NOUN
bptjm-29	141	22	of	of	ADP
bptjm-29	141	23	riluzole	riluzole	PROPN
bptjm-29	141	24	dose	dose	PROPN
bptjm-29	141	25	-	-	PUNCT
bptjm-29	141	26	ranges	range	NOUN
bptjm-29	141	27	on	on	ADP
bptjm-29	141	28	als	als	NOUN
bptjm-29	141	29	patients	patient	NOUN
bptjm-29	141	30	to	to	PART
bptjm-29	141	31	determine	determine	VERB
bptjm-29	141	32	that	that	SCONJ
bptjm-29	141	33	the	the	DET
bptjm-29	141	34	prescription	prescription	NOUN
bptjm-29	141	35	amount	amount	NOUN
bptjm-29	141	36	with	with	ADP
bptjm-29	141	37	the	the	DET
bptjm-29	141	38	best	good	ADJ
bptjm-29	141	39	bene	bene	PROPN
bptjm-29	141	40	�	�	PROPN
bptjm-29	141	41	t	t	PROPN
bptjm-29	141	42	-	-	PUNCT
bptjm-29	141	43	to	to	ADP
bptjm-29	141	44	-	-	PUNCT
bptjm-29	141	45	risk	risk	NOUN
bptjm-29	141	46	ratio	ratio	NOUN
bptjm-29	141	47	is	be	AUX
bptjm-29	141	48	a	a	DET
bptjm-29	141	49	100	100	NUM
bptjm-29	141	50	mg	mg	NOUN
bptjm-29	141	51	dose	dose	NOUN
bptjm-29	141	52	,	,	PUNCT
bptjm-29	141	53	further	further	PROPN
bptjm-29	141	54	con	con	PROPN
bptjm-29	141	55	�	�	PROPN
bptjm-29	141	56	rming	rme	VERB
bptjm-29	141	57	the	the	DET
bptjm-29	141	58	success	success	NOUN
bptjm-29	141	59	of	of	ADP
bptjm-29	141	60	riluzole	riluzole	NOUN
bptjm-29	141	61	.	.	PUNCT
bptjm-29	142	1	while	while	SCONJ
bptjm-29	142	2	a	a	DET
bptjm-29	142	3	complete	complete	ADJ
bptjm-29	142	4	understanding	understanding	NOUN
bptjm-29	142	5	of	of	ADP
bptjm-29	142	6	riluzole	riluzole	NOUN
bptjm-29	142	7	’s	’s	PART
bptjm-29	142	8	mechanism	mechanism	NOUN
bptjm-29	142	9	of	of	ADP
bptjm-29	142	10	action	action	NOUN
bptjm-29	142	11	has	have	AUX
bptjm-29	142	12	not	not	PART
bptjm-29	142	13	been	be	AUX
bptjm-29	142	14	established	establish	VERB
bptjm-29	142	15	,	,	PUNCT
bptjm-29	142	16	properties	property	NOUN
bptjm-29	142	17	including	include	VERB
bptjm-29	142	18	its	its	PRON
bptjm-29	142	19	ability	ability	NOUN
bptjm-29	142	20	to	to	PART
bptjm-29	142	21	inhibit	inhibit	VERB
bptjm-29	142	22	glutamate	glutamate	NOUN
bptjm-29	142	23	release	release	NOUN
bptjm-29	142	24	and	and	CCONJ
bptjm-29	142	25	inactivate	inactivate	VERB
bptjm-29	142	26	voltage	voltage	NOUN
bptjm-29	142	27	-	-	PUNCT
bptjm-29	142	28	gated	gate	VERB
bptjm-29	142	29	sodium	sodium	NOUN
bptjm-29	142	30	channels	channel	NOUN
bptjm-29	142	31	associated	associate	VERB
bptjm-29	142	32	with	with	ADP
bptjm-29	142	33	damaged	damage	VERB
bptjm-29	142	34	neurons	neuron	NOUN
bptjm-29	142	35	are	be	AUX
bptjm-29	142	36	attributed	attribute	VERB
bptjm-29	142	37	to	to	ADP
bptjm-29	142	38	its	its	PRON
bptjm-29	142	39	e	e	PROPN
bptjm-29	142	40	�	�	PROPN
bptjm-29	142	41	ectiveness	ectiveness	NOUN
bptjm-29	142	42	for	for	ADP
bptjm-29	142	43	als31	als31	PROPN
bptjm-29	142	44	.	.	PROPN
bptjm-29	143	1	neuroprotective	neuroprotective	ADJ
bptjm-29	143	2	drugs	drug	NOUN
bptjm-29	143	3	like	like	ADP
bptjm-29	143	4	riluzole	riluzole	NOUN
bptjm-29	143	5	function	function	NOUN
bptjm-29	143	6	by	by	ADP
bptjm-29	143	7	binding	bind	VERB
bptjm-29	143	8	to	to	ADP
bptjm-29	143	9	voltage	voltage	NOUN
bptjm-29	143	10	-	-	PUNCT
bptjm-29	143	11	gated	gate	VERB
bptjm-29	143	12	sodium	sodium	NOUN
bptjm-29	143	13	(	(	PUNCT
bptjm-29	143	14	nav	nav	NOUN
bptjm-29	143	15	)	)	PUNCT
bptjm-29	143	16	channels	channel	NOUN
bptjm-29	143	17	to	to	PART
bptjm-29	143	18	keep	keep	VERB
bptjm-29	143	19	them	they	PRON
bptjm-29	143	20	in	in	ADP
bptjm-29	143	21	an	an	DET
bptjm-29	143	22	open	open	ADJ
bptjm-29	143	23	and	and	CCONJ
bptjm-29	143	24	inactivated	inactivated	ADJ
bptjm-29	143	25	conformation32	conformation32	NOUN
bptjm-29	143	26	.	.	PUNCT
bptjm-29	144	1	it	it	PRON
bptjm-29	144	2	also	also	ADV
bptjm-29	144	3	inhibits	inhibit	VERB
bptjm-29	144	4	na+	na+	ADJ
bptjm-29	144	5	currents	current	NOUN
bptjm-29	144	6	which	which	PRON
bptjm-29	144	7	regulate	regulate	VERB
bptjm-29	144	8	excitability	excitability	NOUN
bptjm-29	144	9	imbalances	imbalance	NOUN
bptjm-29	144	10	to	to	PART
bptjm-29	144	11	prevent	prevent	VERB
bptjm-29	144	12	neuronal	neuronal	ADJ
bptjm-29	144	13	damage	damage	NOUN
bptjm-29	144	14	.	.	PUNCT
bptjm-29	145	1	a	a	DET
bptjm-29	145	2	common	common	ADJ
bptjm-29	145	3	brand	brand	NOUN
bptjm-29	145	4	of	of	ADP
bptjm-29	145	5	riluzole	riluzole	NOUN
bptjm-29	145	6	is	be	AUX
bptjm-29	145	7	rilutek	rilutek	NOUN
bptjm-29	145	8	®	®	NOUN
bptjm-29	145	9	which	which	DET
bptjm-29	145	10	o	o	NOUN
bptjm-29	145	11	�	�	NOUN
bptjm-29	145	12	ers	er	VERB
bptjm-29	145	13	the	the	DET
bptjm-29	145	14	medication	medication	NOUN
bptjm-29	145	15	in	in	ADP
bptjm-29	145	16	the	the	DET
bptjm-29	145	17	form	form	NOUN
bptjm-29	145	18	of	of	ADP
bptjm-29	145	19	a	a	DET
bptjm-29	145	20	prescription	prescription	NOUN
bptjm-29	145	21	pill	pill	NOUN
bptjm-29	145	22	.	.	PUNCT
bptjm-29	146	1	in	in	ADP
bptjm-29	146	2	1995	1995	NUM
bptjm-29	146	3	,	,	PUNCT
bptjm-29	146	4	it	it	PRON
bptjm-29	146	5	became	become	VERB
bptjm-29	146	6	the	the	DET
bptjm-29	146	7	�	�	PROPN
bptjm-29	146	8	rst	rst	PROPN
bptjm-29	146	9	drug	drug	NOUN
bptjm-29	146	10	to	to	PART
bptjm-29	146	11	receive	receive	VERB
bptjm-29	146	12	fda	fda	PROPN
bptjm-29	146	13	approval	approval	NOUN
bptjm-29	146	14	for	for	ADP
bptjm-29	146	15	a	a	DET
bptjm-29	146	16	treatment	treatment	NOUN
bptjm-29	146	17	of	of	ADP
bptjm-29	146	18	als	als	NOUN
bptjm-29	146	19	as	as	SCONJ
bptjm-29	146	20	it	it	PRON
bptjm-29	146	21	proved	prove	VERB
bptjm-29	146	22	to	to	PART
bptjm-29	146	23	“	"	PUNCT
bptjm-29	146	24	extend	extend	VERB
bptjm-29	146	25	survival	survival	NOUN
bptjm-29	146	26	and/or	and/or	CCONJ
bptjm-29	146	27	time	time	NOUN
bptjm-29	146	28	to	to	ADP
bptjm-29	146	29	tracheostomy	tracheostomy	NOUN
bptjm-29	146	30	”	"	PUNCT
bptjm-29	146	31	in	in	ADP
bptjm-29	146	32	clinical	clinical	ADJ
bptjm-29	146	33	trials33	trials33	NOUN
bptjm-29	146	34	.	.	PUNCT
bptjm-29	147	1	in	in	ADP
bptjm-29	147	2	the	the	DET
bptjm-29	147	3	original	original	ADJ
bptjm-29	147	4	clinical	clinical	ADJ
bptjm-29	147	5	trials	trial	NOUN
bptjm-29	147	6	,	,	PUNCT
bptjm-29	147	7	it	it	PRON
bptjm-29	147	8	was	be	AUX
bptjm-29	147	9	estimated	estimate	VERB
bptjm-29	147	10	that	that	SCONJ
bptjm-29	147	11	the	the	DET
bptjm-29	147	12	patients	patient	NOUN
bptjm-29	147	13	treated	treat	VERB
bptjm-29	147	14	with	with	ADP
bptjm-29	147	15	riluzole	riluzole	NOUN
bptjm-29	147	16	have	have	VERB
bptjm-29	147	17	longer	long	ADJ
bptjm-29	147	18	survival	survival	NOUN
bptjm-29	147	19	times	time	NOUN
bptjm-29	147	20	of	of	ADP
bptjm-29	147	21	two	two	NUM
bptjm-29	147	22	to	to	PART
bptjm-29	147	23	three	three	NUM
bptjm-29	147	24	months	month	NOUN
bptjm-29	147	25	.	.	PUNCT
bptjm-29	148	1	however	however	ADV
bptjm-29	148	2	,	,	PUNCT
bptjm-29	148	3	a	a	DET
bptjm-29	148	4	retrospective	retrospective	ADJ
bptjm-29	148	5	statistical	statistical	ADJ
bptjm-29	148	6	analysis	analysis	NOUN
bptjm-29	148	7	on	on	ADP
bptjm-29	148	8	population	population	NOUN
bptjm-29	148	9	studies	study	NOUN
bptjm-29	148	10	of	of	ADP
bptjm-29	148	11	als	als	NOUN
bptjm-29	148	12	compared	compare	VERB
bptjm-29	148	13	the	the	DET
bptjm-29	148	14	mean	mean	ADJ
bptjm-29	148	15	survival	survival	NOUN
bptjm-29	148	16	rate	rate	NOUN
bptjm-29	148	17	between	between	ADP
bptjm-29	148	18	treated	treat	VERB
bptjm-29	148	19	and	and	CCONJ
bptjm-29	148	20	non	non	ADJ
bptjm-29	148	21	-	-	ADJ
bptjm-29	148	22	treated	treat	VERB
bptjm-29	148	23	patients	patient	NOUN
bptjm-29	148	24	to	to	PART
bptjm-29	148	25	suggest	suggest	VERB
bptjm-29	148	26	that	that	SCONJ
bptjm-29	148	27	riluzole	riluzole	NOUN
bptjm-29	148	28	may	may	AUX
bptjm-29	148	29	even	even	ADV
bptjm-29	148	30	extend	extend	VERB
bptjm-29	148	31	survival	survival	NOUN
bptjm-29	148	32	by	by	ADP
bptjm-29	148	33	six	six	NUM
bptjm-29	148	34	to	to	PART
bptjm-29	148	35	19	19	NUM
bptjm-29	148	36	months	month	NOUN
bptjm-29	148	37	,	,	PUNCT
bptjm-29	148	38	longer	long	ADV
bptjm-29	148	39	than	than	ADP
bptjm-29	148	40	the	the	DET
bptjm-29	148	41	original	original	ADJ
bptjm-29	148	42	expectancy34	expectancy34	NOUN
bptjm-29	148	43	.	.	PUNCT
bptjm-29	149	1	although	although	SCONJ
bptjm-29	149	2	riluzole	riluzole	NOUN
bptjm-29	149	3	is	be	AUX
bptjm-29	149	4	a	a	DET
bptjm-29	149	5	favorable	favorable	ADJ
bptjm-29	149	6	option	option	NOUN
bptjm-29	149	7	,	,	PUNCT
bptjm-29	149	8	advances	advance	NOUN
bptjm-29	149	9	in	in	ADP
bptjm-29	149	10	pharmacology	pharmacology	NOUN
bptjm-29	149	11	have	have	AUX
bptjm-29	149	12	been	be	AUX
bptjm-29	149	13	geared	gear	VERB
bptjm-29	149	14	towards	towards	ADP
bptjm-29	149	15	new	new	ADJ
bptjm-29	149	16	drugs	drug	NOUN
bptjm-29	149	17	and	and	CCONJ
bptjm-29	149	18	additive	additive	ADJ
bptjm-29	149	19	treatments	treatment	NOUN
bptjm-29	149	20	to	to	PART
bptjm-29	149	21	improve	improve	VERB
bptjm-29	149	22	e	e	NOUN
bptjm-29	149	23	�	�	NOUN
bptjm-29	149	24	cacy	cacy	NOUN
bptjm-29	149	25	.	.	PUNCT
bptjm-29	150	1	in	in	ADP
bptjm-29	150	2	may	may	PROPN
bptjm-29	150	3	of	of	ADP
bptjm-29	150	4	2017	2017	NUM
bptjm-29	150	5	,	,	PUNCT
bptjm-29	150	6	the	the	DET
bptjm-29	150	7	fda	fda	PROPN
bptjm-29	150	8	approved	approve	VERB
bptjm-29	150	9	the	the	DET
bptjm-29	150	10	second	second	ADJ
bptjm-29	150	11	targeted	target	VERB
bptjm-29	150	12	drug	drug	NOUN
bptjm-29	150	13	intended	intend	VERB
bptjm-29	150	14	to	to	PART
bptjm-29	150	15	slow	slow	VERB
bptjm-29	150	16	als	als	NOUN
bptjm-29	150	17	progression	progression	NOUN
bptjm-29	150	18	:	:	PUNCT
bptjm-29	150	19	edaravone	edaravone	NOUN
bptjm-29	150	20	.	.	PUNCT
bptjm-29	151	1	the	the	DET
bptjm-29	151	2	most	most	ADV
bptjm-29	151	3	common	common	ADJ
bptjm-29	151	4	formulation	formulation	NOUN
bptjm-29	151	5	is	be	AUX
bptjm-29	151	6	radicava	radicava	NOUN
bptjm-29	151	7	iv	iv	NUM
bptjm-29	151	8	which	which	PRON
bptjm-29	151	9	has	have	AUX
bptjm-29	151	10	shown	show	VERB
bptjm-29	151	11	signs	sign	NOUN
bptjm-29	151	12	of	of	ADP
bptjm-29	151	13	selective	selective	ADJ
bptjm-29	151	14	e	e	NOUN
bptjm-29	151	15	�	�	NOUN
bptjm-29	151	16	ectuality35	ectuality35	NOUN
bptjm-29	151	17	.	.	PUNCT
bptjm-29	152	1	unlike	unlike	ADP
bptjm-29	152	2	riluzole	riluzole	NOUN
bptjm-29	152	3	which	which	PRON
bptjm-29	152	4	targets	target	VERB
bptjm-29	152	5	excitotoxicity	excitotoxicity	NOUN
bptjm-29	152	6	,	,	PUNCT
bptjm-29	152	7	edaravone	edaravone	NOUN
bptjm-29	152	8	is	be	AUX
bptjm-29	152	9	an	an	DET
bptjm-29	152	10	antioxidant	antioxidant	NOUN
bptjm-29	152	11	–	–	PUNCT
bptjm-29	152	12	a	a	DET
bptjm-29	152	13	compound	compound	NOUN
bptjm-29	152	14	inhibiting	inhibit	VERB
bptjm-29	152	15	lipid	lipid	NOUN
bptjm-29	152	16	oxidation	oxidation	NOUN
bptjm-29	152	17	to	to	PART
bptjm-29	152	18	prevent	prevent	VERB
bptjm-29	152	19	the	the	DET
bptjm-29	152	20	production	production	NOUN
bptjm-29	152	21	of	of	ADP
bptjm-29	152	22	free	free	ADJ
bptjm-29	152	23	radicals	radical	NOUN
bptjm-29	152	24	and	and	CCONJ
bptjm-29	152	25	chain	chain	NOUN
bptjm-29	152	26	reactions	reaction	NOUN
bptjm-29	152	27	that	that	PRON
bptjm-29	152	28	may	may	AUX
bptjm-29	152	29	induce	induce	VERB
bptjm-29	152	30	cell	cell	NOUN
bptjm-29	152	31	damage36	damage36	NOUN
bptjm-29	152	32	.	.	PUNCT
bptjm-29	153	1	by	by	ADP
bptjm-29	153	2	reacting	react	VERB
bptjm-29	153	3	with	with	ADP
bptjm-29	153	4	radical	radical	ADJ
bptjm-29	153	5	species	specie	NOUN
bptjm-29	153	6	,	,	PUNCT
bptjm-29	153	7	this	this	DET
bptjm-29	153	8	antioxidant	antioxidant	NOUN
bptjm-29	153	9	captures	capture	NOUN
bptjm-29	153	10	unstable	unstable	ADJ
bptjm-29	153	11	reactive	reactive	ADJ
bptjm-29	153	12	oxygen	oxygen	NOUN
bptjm-29	153	13	species	specie	NOUN
bptjm-29	153	14	because	because	SCONJ
bptjm-29	153	15	a	a	DET
bptjm-29	153	16	large	large	ADJ
bptjm-29	153	17	concentration	concentration	NOUN
bptjm-29	153	18	of	of	ADP
bptjm-29	153	19	these	these	DET
bptjm-29	153	20	molecules	molecule	NOUN
bptjm-29	153	21	contributes	contribute	VERB
bptjm-29	153	22	to	to	ADP
bptjm-29	153	23	the	the	DET
bptjm-29	153	24	berkeley	berkeley	PROPN
bptjm-29	153	25	pharma	pharma	PROPN
bptjm-29	153	26	tech	tech	NOUN
bptjm-29	153	27	journal	journal	NOUN
bptjm-29	153	28	of	of	ADP
bptjm-29	153	29	medicine	medicine	NOUN
bptjm-29	154	1	|	|	ADV
bptjm-29	154	2	79	79	NUM
bptjm-29	154	3	https://www.zotero.org/google-docs/?qtliq5	https://www.zotero.org/google-docs/?qtliq5	NOUN
bptjm-29	154	4	https://www.zotero.org/google-docs/?zcoayd	https://www.zotero.org/google-docs/?zcoayd	PROPN
bptjm-29	154	5	https://www.zotero.org/google-docs/?4izppz	https://www.zotero.org/google-docs/?4izppz	VERB
bptjm-29	154	6	https://www.zotero.org/google-docs/?pwqioz	https://www.zotero.org/google-docs/?pwqioz	ADJ
bptjm-29	154	7	https://www.zotero.org/google-docs/?ei1suf	https://www.zotero.org/google-docs/?ei1suf	PROPN
bptjm-29	155	1	https://www.zotero.org/google-docs/?wankcq	https://www.zotero.org/google-docs/?wankcq	ADJ
bptjm-29	155	2	https://www.zotero.org/google-docs/?zfweia	https://www.zotero.org/google-docs/?zfweia	NOUN
bptjm-29	155	3	degeneration	degeneration	NOUN
bptjm-29	155	4	of	of	ADP
bptjm-29	155	5	motor	motor	NOUN
bptjm-29	155	6	neurons	neuron	NOUN
bptjm-29	155	7	.	.	PUNCT
bptjm-29	156	1	an	an	DET
bptjm-29	156	2	active	active	ADJ
bptjm-29	156	3	phase	phase	NOUN
bptjm-29	156	4	3	3	NUM
bptjm-29	156	5	clinical	clinical	ADJ
bptjm-29	156	6	trial	trial	NOUN
bptjm-29	156	7	is	be	AUX
bptjm-29	156	8	currently	currently	ADV
bptjm-29	156	9	evaluating	evaluate	VERB
bptjm-29	156	10	the	the	DET
bptjm-29	156	11	safety	safety	NOUN
bptjm-29	156	12	and	and	CCONJ
bptjm-29	156	13	e	e	NOUN
bptjm-29	156	14	�	�	NOUN
bptjm-29	156	15	cacy	cacy	NOUN
bptjm-29	156	16	of	of	ADP
bptjm-29	156	17	oral	oral	ADJ
bptjm-29	156	18	edaravone	edaravone	NOUN
bptjm-29	156	19	for	for	ADP
bptjm-29	156	20	als	als	NOUN
bptjm-29	156	21	patients	patient	NOUN
bptjm-29	156	22	based	base	VERB
bptjm-29	156	23	on	on	ADP
bptjm-29	156	24	the	the	DET
bptjm-29	156	25	als	als	NOUN
bptjm-29	156	26	functional	functional	ADJ
bptjm-29	156	27	rating	rating	NOUN
bptjm-29	156	28	scalerevised	scalerevise	VERB
bptjm-29	156	29	(	(	PUNCT
bptjm-29	156	30	alsfrs	alsfrs	NOUN
bptjm-29	156	31	-	-	PUNCT
bptjm-29	156	32	r	r	NOUN
bptjm-29	156	33	)	)	PUNCT
bptjm-29	156	34	score	score	NOUN
bptjm-29	156	35	which	which	PRON
bptjm-29	156	36	observes	observe	VERB
bptjm-29	156	37	lifestyle	lifestyle	NOUN
bptjm-29	156	38	changes	change	NOUN
bptjm-29	156	39	such	such	ADJ
bptjm-29	156	40	as	as	ADP
bptjm-29	156	41	independence	independence	NOUN
bptjm-29	156	42	,	,	PUNCT
bptjm-29	156	43	speech	speech	NOUN
bptjm-29	156	44	,	,	PUNCT
bptjm-29	156	45	and	and	CCONJ
bptjm-29	156	46	mobility37	mobility37	NOUN
bptjm-29	156	47	.	.	PUNCT
bptjm-29	157	1	the	the	DET
bptjm-29	157	2	�	�	PROPN
bptjm-29	157	3	rst	rst	PROPN
bptjm-29	157	4	version	version	NOUN
bptjm-29	157	5	of	of	ADP
bptjm-29	157	6	this	this	DET
bptjm-29	157	7	drug	drug	NOUN
bptjm-29	157	8	was	be	AUX
bptjm-29	157	9	administered	administer	VERB
bptjm-29	157	10	via	via	ADP
bptjm-29	157	11	intravenous	intravenous	ADJ
bptjm-29	157	12	infusion	infusion	NOUN
bptjm-29	157	13	,	,	PUNCT
bptjm-29	157	14	a	a	DET
bptjm-29	157	15	drug	drug	NOUN
bptjm-29	157	16	-	-	PUNCT
bptjm-29	157	17	delivery	delivery	NOUN
bptjm-29	157	18	method	method	NOUN
bptjm-29	157	19	administered	administer	VERB
bptjm-29	157	20	directly	directly	ADV
bptjm-29	157	21	into	into	ADP
bptjm-29	157	22	a	a	DET
bptjm-29	157	23	vein	vein	NOUN
bptjm-29	157	24	using	use	VERB
bptjm-29	157	25	a	a	DET
bptjm-29	157	26	cannula	cannula	NOUN
bptjm-29	157	27	,	,	PUNCT
bptjm-29	157	28	which	which	PRON
bptjm-29	157	29	received	receive	VERB
bptjm-29	157	30	fda	fda	PROPN
bptjm-29	157	31	approval	approval	NOUN
bptjm-29	157	32	on	on	ADP
bptjm-29	157	33	may	may	PROPN
bptjm-29	157	34	5	5	NUM
bptjm-29	157	35	,	,	PUNCT
bptjm-29	157	36	2017	2017	NUM
bptjm-29	157	37	.	.	PUNCT
bptjm-29	158	1	the	the	DET
bptjm-29	158	2	doses	dose	NOUN
bptjm-29	158	3	are	be	AUX
bptjm-29	158	4	given	give	VERB
bptjm-29	158	5	in	in	ADP
bptjm-29	158	6	slow	slow	ADJ
bptjm-29	158	7	and	and	CCONJ
bptjm-29	158	8	set	set	VERB
bptjm-29	158	9	treatment	treatment	NOUN
bptjm-29	158	10	cycles	cycle	NOUN
bptjm-29	158	11	to	to	PART
bptjm-29	158	12	observe	observe	VERB
bptjm-29	158	13	for	for	ADP
bptjm-29	158	14	signs	sign	NOUN
bptjm-29	158	15	of	of	ADP
bptjm-29	158	16	hypersensitivity	hypersensitivity	NOUN
bptjm-29	158	17	.	.	PUNCT
bptjm-29	159	1	the	the	DET
bptjm-29	159	2	infusion	infusion	NOUN
bptjm-29	159	3	can	can	AUX
bptjm-29	159	4	take	take	VERB
bptjm-29	159	5	up	up	ADP
bptjm-29	159	6	to	to	ADP
bptjm-29	159	7	an	an	DET
bptjm-29	159	8	hour	hour	NOUN
bptjm-29	159	9	and	and	CCONJ
bptjm-29	159	10	must	must	AUX
bptjm-29	159	11	be	be	AUX
bptjm-29	159	12	performed	perform	VERB
bptjm-29	159	13	by	by	ADP
bptjm-29	159	14	a	a	DET
bptjm-29	159	15	healthcare	healthcare	NOUN
bptjm-29	159	16	provider	provider	NOUN
bptjm-29	159	17	.	.	PUNCT
bptjm-29	160	1	on	on	ADP
bptjm-29	160	2	may	may	PROPN
bptjm-29	160	3	12	12	NUM
bptjm-29	160	4	,	,	PUNCT
bptjm-29	160	5	2022	2022	NUM
bptjm-29	160	6	,	,	PUNCT
bptjm-29	160	7	radicava	radicava	NOUN
bptjm-29	160	8	oral	oral	ADJ
bptjm-29	160	9	suspension	suspension	NOUN
bptjm-29	160	10	was	be	AUX
bptjm-29	160	11	fda	fda	PROPN
bptjm-29	160	12	approved	approve	VERB
bptjm-29	160	13	,	,	PUNCT
bptjm-29	160	14	which	which	PRON
bptjm-29	160	15	grants	grant	VERB
bptjm-29	160	16	the	the	DET
bptjm-29	160	17	user	user	NOUN
bptjm-29	160	18	more	more	ADJ
bptjm-29	160	19	�	�	PROPN
bptjm-29	160	20	exibility	exibility	NOUN
bptjm-29	160	21	in	in	ADP
bptjm-29	160	22	administering	administer	VERB
bptjm-29	160	23	treatment	treatment	NOUN
bptjm-29	160	24	.	.	PUNCT
bptjm-29	161	1	prior	prior	ADV
bptjm-29	161	2	to	to	ADP
bptjm-29	161	3	radicava	radicava	VERB
bptjm-29	161	4	’s	’s	PART
bptjm-29	161	5	oral	oral	ADJ
bptjm-29	161	6	formulation	formulation	NOUN
bptjm-29	161	7	,	,	PUNCT
bptjm-29	161	8	di	di	NOUN
bptjm-29	161	9	�	�	NOUN
bptjm-29	161	10	erences	erence	NOUN
bptjm-29	161	11	between	between	ADP
bptjm-29	161	12	the	the	DET
bptjm-29	161	13	two	two	NUM
bptjm-29	161	14	treatments	treatment	NOUN
bptjm-29	161	15	such	such	ADJ
bptjm-29	161	16	as	as	ADP
bptjm-29	161	17	absorption	absorption	NOUN
bptjm-29	161	18	and	and	CCONJ
bptjm-29	161	19	distribution	distribution	NOUN
bptjm-29	161	20	were	be	AUX
bptjm-29	161	21	more	more	ADV
bptjm-29	161	22	observable38	observable38	ADJ
bptjm-29	161	23	.	.	PUNCT
bptjm-29	162	1	while	while	SCONJ
bptjm-29	162	2	riluzole	riluzole	NOUN
bptjm-29	162	3	is	be	AUX
bptjm-29	162	4	in	in	ADP
bptjm-29	162	5	a	a	DET
bptjm-29	162	6	more	more	ADV
bptjm-29	162	7	convenient	convenient	ADJ
bptjm-29	162	8	tablet	tablet	NOUN
bptjm-29	162	9	form	form	NOUN
bptjm-29	162	10	,	,	PUNCT
bptjm-29	162	11	injections	injection	NOUN
bptjm-29	162	12	of	of	ADP
bptjm-29	162	13	edaravone	edaravone	NOUN
bptjm-29	162	14	do	do	AUX
bptjm-29	162	15	not	not	PART
bptjm-29	162	16	face	face	VERB
bptjm-29	162	17	issues	issue	NOUN
bptjm-29	162	18	with	with	ADP
bptjm-29	162	19	absorption	absorption	NOUN
bptjm-29	162	20	,	,	PUNCT
bptjm-29	162	21	and	and	CCONJ
bptjm-29	162	22	there	there	PRON
bptjm-29	162	23	may	may	AUX
bptjm-29	162	24	be	be	AUX
bptjm-29	162	25	more	more	ADJ
bptjm-29	162	26	transport	transport	NOUN
bptjm-29	162	27	across	across	ADP
bptjm-29	162	28	the	the	DET
bptjm-29	162	29	brain	brain	NOUN
bptjm-29	162	30	blood	blood	NOUN
bptjm-29	162	31	barrier	barrier	NOUN
bptjm-29	162	32	(	(	PUNCT
bptjm-29	162	33	bbb	bbb	PROPN
bptjm-29	162	34	)	)	PUNCT
bptjm-29	162	35	,	,	PUNCT
bptjm-29	162	36	a	a	DET
bptjm-29	162	37	semipermeable	semipermeable	ADJ
bptjm-29	162	38	membrane	membrane	NOUN
bptjm-29	162	39	facilitating	facilitate	VERB
bptjm-29	162	40	the	the	DET
bptjm-29	162	41	transport	transport	NOUN
bptjm-29	162	42	of	of	ADP
bptjm-29	162	43	molecules	molecule	NOUN
bptjm-29	162	44	and	and	CCONJ
bptjm-29	162	45	substances	substance	NOUN
bptjm-29	162	46	from	from	ADP
bptjm-29	162	47	the	the	DET
bptjm-29	162	48	bloodstream	bloodstream	NOUN
bptjm-29	162	49	to	to	ADP
bptjm-29	162	50	the	the	DET
bptjm-29	162	51	brain	brain	NOUN
bptjm-29	162	52	.	.	PUNCT
bptjm-29	163	1	cohort	cohort	NOUN
bptjm-29	163	2	studies	study	NOUN
bptjm-29	163	3	have	have	AUX
bptjm-29	163	4	also	also	ADV
bptjm-29	163	5	observed	observe	VERB
bptjm-29	163	6	the	the	DET
bptjm-29	163	7	e	e	NOUN
bptjm-29	163	8	�	�	PROPN
bptjm-29	163	9	ects	ect	NOUN
bptjm-29	163	10	of	of	ADP
bptjm-29	163	11	using	use	VERB
bptjm-29	163	12	intravenous	intravenous	ADJ
bptjm-29	163	13	edaravone	edaravone	NOUN
bptjm-29	163	14	in	in	ADP
bptjm-29	163	15	conjunction	conjunction	NOUN
bptjm-29	163	16	with	with	ADP
bptjm-29	163	17	riluzole	riluzole	NOUN
bptjm-29	163	18	,	,	PUNCT
bptjm-29	163	19	but	but	CCONJ
bptjm-29	163	20	there	there	PRON
bptjm-29	163	21	was	be	VERB
bptjm-29	163	22	no	no	DET
bptjm-29	163	23	improvement	improvement	NOUN
bptjm-29	163	24	in	in	ADP
bptjm-29	163	25	als	als	NOUN
bptjm-29	163	26	in	in	ADP
bptjm-29	163	27	comparison	comparison	NOUN
bptjm-29	163	28	to	to	ADP
bptjm-29	163	29	standard	standard	ADJ
bptjm-29	163	30	riluzole	riluzole	NOUN
bptjm-29	163	31	therapy39	therapy39	NOUN
bptjm-29	163	32	.	.	PUNCT
bptjm-29	164	1	since	since	SCONJ
bptjm-29	164	2	the	the	DET
bptjm-29	164	3	issue	issue	NOUN
bptjm-29	164	4	of	of	ADP
bptjm-29	164	5	convenience	convenience	NOUN
bptjm-29	164	6	is	be	AUX
bptjm-29	164	7	no	no	ADV
bptjm-29	164	8	longer	long	ADV
bptjm-29	164	9	a	a	DET
bptjm-29	164	10	dividing	dividing	NOUN
bptjm-29	164	11	factor	factor	NOUN
bptjm-29	164	12	,	,	PUNCT
bptjm-29	164	13	new	new	ADJ
bptjm-29	164	14	research	research	NOUN
bptjm-29	164	15	is	be	AUX
bptjm-29	164	16	geared	gear	VERB
bptjm-29	164	17	towards	towards	ADP
bptjm-29	164	18	testing	test	VERB
bptjm-29	164	19	the	the	DET
bptjm-29	164	20	variation	variation	NOUN
bptjm-29	164	21	between	between	ADP
bptjm-29	164	22	both	both	DET
bptjm-29	164	23	oral	oral	ADJ
bptjm-29	164	24	forms	form	NOUN
bptjm-29	164	25	in	in	ADP
bptjm-29	164	26	e	e	NOUN
bptjm-29	164	27	�	�	NOUN
bptjm-29	164	28	cacy	cacy	NOUN
bptjm-29	164	29	for	for	ADP
bptjm-29	164	30	als	als	NOUN
bptjm-29	164	31	treatment	treatment	NOUN
bptjm-29	164	32	.	.	PUNCT
bptjm-29	165	1	another	another	DET
bptjm-29	165	2	novel	novel	ADJ
bptjm-29	165	3	drug	drug	NOUN
bptjm-29	165	4	that	that	PRON
bptjm-29	165	5	is	be	AUX
bptjm-29	165	6	currently	currently	ADV
bptjm-29	165	7	being	be	AUX
bptjm-29	165	8	tested	test	VERB
bptjm-29	165	9	in	in	ADP
bptjm-29	165	10	clinical	clinical	ADJ
bptjm-29	165	11	trials	trial	NOUN
bptjm-29	165	12	is	be	AUX
bptjm-29	165	13	amx0035	amx0035	ADJ
bptjm-29	165	14	,	,	PUNCT
bptjm-29	165	15	used	use	VERB
bptjm-29	165	16	as	as	ADP
bptjm-29	165	17	an	an	DET
bptjm-29	165	18	oral	oral	ADJ
bptjm-29	165	19	combination	combination	NOUN
bptjm-29	165	20	therapy	therapy	NOUN
bptjm-29	165	21	of	of	ADP
bptjm-29	165	22	sodium	sodium	NOUN
bptjm-29	165	23	phenylbutyrate	phenylbutyrate	NOUN
bptjm-29	165	24	(	(	PUNCT
bptjm-29	165	25	spb	spb	PROPN
bptjm-29	165	26	)	)	PUNCT
bptjm-29	165	27	and	and	CCONJ
bptjm-29	165	28	taurursodiol	taurursodiol	NOUN
bptjm-29	165	29	(	(	PUNCT
bptjm-29	165	30	turso	turso	NOUN
bptjm-29	165	31	)	)	PUNCT
bptjm-29	165	32	to	to	PART
bptjm-29	165	33	block	block	VERB
bptjm-29	165	34	cell	cell	NOUN
bptjm-29	165	35	death	death	NOUN
bptjm-29	165	36	mechanisms37	mechanisms37	PROPN
bptjm-29	165	37	.	.	PUNCT
bptjm-29	166	1	amx0035	amx0035	PROPN
bptjm-29	166	2	was	be	AUX
bptjm-29	166	3	developed	develop	VERB
bptjm-29	166	4	by	by	ADP
bptjm-29	166	5	amylyx	amylyx	PROPN
bptjm-29	166	6	pharmaceuticals	pharmaceuticals	PROPN
bptjm-29	166	7	,	,	PUNCT
bptjm-29	166	8	inc	inc	PROPN
bptjm-29	166	9	.	.	PROPN
bptjm-29	166	10	,	,	PUNCT
bptjm-29	166	11	and	and	CCONJ
bptjm-29	166	12	on	on	ADP
bptjm-29	166	13	september	september	PROPN
bptjm-29	166	14	29	29	NUM
bptjm-29	166	15	,	,	PUNCT
bptjm-29	166	16	2022	2022	NUM
bptjm-29	166	17	,	,	PUNCT
bptjm-29	166	18	the	the	DET
bptjm-29	166	19	fda	fda	PROPN
bptjm-29	166	20	approved	approve	VERB
bptjm-29	166	21	this	this	DET
bptjm-29	166	22	drug	drug	NOUN
bptjm-29	166	23	as	as	ADP
bptjm-29	166	24	the	the	DET
bptjm-29	166	25	newest	new	ADJ
bptjm-29	166	26	therapeutic	therapeutic	ADJ
bptjm-29	166	27	for	for	ADP
bptjm-29	166	28	als41	als41	ADJ
bptjm-29	166	29	.	.	PUNCT
bptjm-29	167	1	it	it	PRON
bptjm-29	167	2	will	will	AUX
bptjm-29	167	3	be	be	AUX
bptjm-29	167	4	sold	sell	VERB
bptjm-29	167	5	to	to	ADP
bptjm-29	167	6	patients	patient	NOUN
bptjm-29	167	7	in	in	ADP
bptjm-29	167	8	the	the	DET
bptjm-29	167	9	u.s	u.s	PROPN
bptjm-29	167	10	.	.	PROPN
bptjm-29	167	11	under	under	ADP
bptjm-29	167	12	the	the	DET
bptjm-29	167	13	name	name	NOUN
bptjm-29	167	14	relyvrio	relyvrio	NOUN
bptjm-29	167	15	,	,	PUNCT
bptjm-29	167	16	and	and	CCONJ
bptjm-29	167	17	it	it	PRON
bptjm-29	167	18	proved	prove	VERB
bptjm-29	167	19	successful	successful	ADJ
bptjm-29	167	20	in	in	ADP
bptjm-29	167	21	clinical	clinical	ADJ
bptjm-29	167	22	trials	trial	NOUN
bptjm-29	167	23	,	,	PUNCT
bptjm-29	167	24	with	with	ADP
bptjm-29	167	25	patients	patient	NOUN
bptjm-29	167	26	reporting	report	VERB
bptjm-29	167	27	less	less	ADJ
bptjm-29	167	28	als	als	NOUN
bptjm-29	167	29	symptoms	symptom	NOUN
bptjm-29	167	30	under	under	ADP
bptjm-29	167	31	the	the	DET
bptjm-29	167	32	treatment	treatment	NOUN
bptjm-29	167	33	in	in	ADP
bptjm-29	167	34	comparison	comparison	NOUN
bptjm-29	167	35	to	to	ADP
bptjm-29	167	36	a	a	DET
bptjm-29	167	37	placebo40	placebo40	NOUN
bptjm-29	167	38	.	.	PUNCT
bptjm-29	168	1	in	in	ADP
bptjm-29	168	2	the	the	DET
bptjm-29	168	3	brie	brie	PROPN
bptjm-29	168	4	�	�	PROPN
bptjm-29	168	5	ngs	ng	NOUN
bptjm-29	168	6	between	between	ADP
bptjm-29	168	7	the	the	DET
bptjm-29	168	8	company	company	NOUN
bptjm-29	168	9	and	and	CCONJ
bptjm-29	168	10	the	the	DET
bptjm-29	168	11	fda	fda	PROPN
bptjm-29	168	12	,	,	PUNCT
bptjm-29	168	13	it	it	PRON
bptjm-29	168	14	was	be	AUX
bptjm-29	168	15	also	also	ADV
bptjm-29	168	16	noted	note	VERB
bptjm-29	168	17	in	in	ADP
bptjm-29	168	18	the	the	DET
bptjm-29	168	19	results	result	NOUN
bptjm-29	168	20	of	of	ADP
bptjm-29	168	21	their	their	PRON
bptjm-29	168	22	clinical	clinical	ADJ
bptjm-29	168	23	trials	trial	NOUN
bptjm-29	168	24	that	that	PRON
bptjm-29	168	25	patients	patient	NOUN
bptjm-29	168	26	who	who	PRON
bptjm-29	168	27	were	be	AUX
bptjm-29	168	28	randomly	randomly	ADV
bptjm-29	168	29	assigned	assign	VERB
bptjm-29	168	30	to	to	PART
bptjm-29	168	31	receive	receive	VERB
bptjm-29	168	32	amx0035	amx0035	NOUN
bptjm-29	168	33	also	also	ADV
bptjm-29	168	34	showed	show	VERB
bptjm-29	168	35	statistically	statistically	ADV
bptjm-29	168	36	signi	signi	ADJ
bptjm-29	168	37	�	�	NOUN
bptjm-29	168	38	cant	cant	VERB
bptjm-29	168	39	increases	increase	NOUN
bptjm-29	168	40	in	in	ADP
bptjm-29	168	41	survival	survival	NOUN
bptjm-29	168	42	duration	duration	NOUN
bptjm-29	168	43	of	of	ADP
bptjm-29	168	44	around	around	ADP
bptjm-29	168	45	�	�	PROPN
bptjm-29	168	46	ve	ve	NOUN
bptjm-29	168	47	months	month	NOUN
bptjm-29	168	48	longer	long	ADV
bptjm-29	168	49	than	than	ADP
bptjm-29	168	50	the	the	DET
bptjm-29	168	51	placebo	placebo	NOUN
bptjm-29	168	52	.	.	PUNCT
bptjm-29	169	1	this	this	DET
bptjm-29	169	2	value	value	NOUN
bptjm-29	169	3	is	be	AUX
bptjm-29	169	4	comparable	comparable	ADJ
bptjm-29	169	5	to	to	ADP
bptjm-29	169	6	berkeley	berkeley	PROPN
bptjm-29	169	7	pharma	pharma	PROPN
bptjm-29	169	8	tech	tech	NOUN
bptjm-29	169	9	journal	journal	NOUN
bptjm-29	169	10	of	of	ADP
bptjm-29	169	11	medicine	medicine	NOUN
bptjm-29	170	1	|	|	ADV
bptjm-29	170	2	80	80	NUM
bptjm-29	170	3	https://www.zotero.org/google-docs/?o3bfwg	https://www.zotero.org/google-docs/?o3bfwg	NOUN
bptjm-29	170	4	https://www.zotero.org/google-docs/?imtdv2	https://www.zotero.org/google-docs/?imtdv2	PROPN
bptjm-29	170	5	https://www.zotero.org/google-docs/?07j7p8	https://www.zotero.org/google-docs/?07j7p8	PROPN
bptjm-29	170	6	https://www.zotero.org/google-docs/?zjvu0o	https://www.zotero.org/google-docs/?zjvu0o	PROPN
bptjm-29	170	7	https://www.zotero.org/google-docs/?qszaxt	https://www.zotero.org/google-docs/?qszaxt	NOUN
bptjm-29	170	8	the	the	DET
bptjm-29	170	9	survival	survival	PROPN
bptjm-29	170	10	bene	bene	PROPN
bptjm-29	170	11	�	�	PROPN
bptjm-29	170	12	ts	ts	ADP
bptjm-29	170	13	of	of	ADP
bptjm-29	170	14	riluzole	riluzole	NOUN
bptjm-29	170	15	and	and	CCONJ
bptjm-29	170	16	edaravone	edaravone	NOUN
bptjm-29	170	17	which	which	PRON
bptjm-29	170	18	are	be	AUX
bptjm-29	170	19	three	three	NUM
bptjm-29	170	20	and	and	CCONJ
bptjm-29	170	21	six	six	NUM
bptjm-29	170	22	months	month	NOUN
bptjm-29	170	23	,	,	PUNCT
bptjm-29	170	24	respectively	respectively	ADV
bptjm-29	170	25	.	.	PUNCT
bptjm-29	171	1	after	after	ADP
bptjm-29	171	2	nearly	nearly	ADV
bptjm-29	171	3	a	a	PRON
bptjm-29	171	4	decade	decade	NOUN
bptjm-29	171	5	of	of	ADP
bptjm-29	171	6	developing	develop	VERB
bptjm-29	171	7	a	a	DET
bptjm-29	171	8	new	new	ADJ
bptjm-29	171	9	combination	combination	NOUN
bptjm-29	171	10	drug	drug	NOUN
bptjm-29	171	11	for	for	ADP
bptjm-29	171	12	als	al	NOUN
bptjm-29	171	13	,	,	PUNCT
bptjm-29	171	14	amylyx	amylyx	PROPN
bptjm-29	171	15	’s	’s	PART
bptjm-29	171	16	co	co	NOUN
bptjm-29	171	17	-	-	ADJ
bptjm-29	171	18	founders	founder	NOUN
bptjm-29	171	19	justin	justin	PROPN
bptjm-29	171	20	klee	klee	PROPN
bptjm-29	171	21	and	and	CCONJ
bptjm-29	171	22	josh	josh	PROPN
bptjm-29	171	23	cohen	cohen	PROPN
bptjm-29	171	24	became	become	VERB
bptjm-29	171	25	successful	successful	ADJ
bptjm-29	171	26	at	at	ADP
bptjm-29	171	27	providing	provide	VERB
bptjm-29	171	28	the	the	DET
bptjm-29	171	29	als	als	NOUN
bptjm-29	171	30	community	community	NOUN
bptjm-29	171	31	with	with	ADP
bptjm-29	171	32	newfound	newfound	NOUN
bptjm-29	171	33	hope	hope	NOUN
bptjm-29	171	34	for	for	ADP
bptjm-29	171	35	an	an	DET
bptjm-29	171	36	improved	improved	ADJ
bptjm-29	171	37	lifestyle	lifestyle	NOUN
bptjm-29	171	38	.	.	PUNCT
bptjm-29	172	1	this	this	DET
bptjm-29	172	2	drug	drug	NOUN
bptjm-29	172	3	targets	target	NOUN
bptjm-29	172	4	two	two	NUM
bptjm-29	172	5	of	of	ADP
bptjm-29	172	6	the	the	DET
bptjm-29	172	7	various	various	ADJ
bptjm-29	172	8	mechanisms	mechanism	NOUN
bptjm-29	172	9	contributing	contribute	VERB
bptjm-29	172	10	to	to	ADP
bptjm-29	172	11	disease	disease	NOUN
bptjm-29	172	12	propagation	propagation	NOUN
bptjm-29	172	13	:	:	PUNCT
bptjm-29	172	14	er	er	INTJ
bptjm-29	172	15	stress	stress	NOUN
bptjm-29	172	16	and	and	CCONJ
bptjm-29	172	17	mitochondrial	mitochondrial	ADJ
bptjm-29	172	18	stress	stress	NOUN
bptjm-29	172	19	.	.	PUNCT
bptjm-29	173	1	spb	spb	PROPN
bptjm-29	173	2	alleviates	alleviate	VERB
bptjm-29	173	3	toxicity	toxicity	NOUN
bptjm-29	173	4	from	from	ADP
bptjm-29	173	5	er	er	INTJ
bptjm-29	173	6	stress	stress	NOUN
bptjm-29	173	7	,	,	PUNCT
bptjm-29	173	8	increasing	increase	VERB
bptjm-29	173	9	the	the	DET
bptjm-29	173	10	number	number	NOUN
bptjm-29	173	11	of	of	ADP
bptjm-29	173	12	heat	heat	NOUN
bptjm-29	173	13	-	-	PUNCT
bptjm-29	173	14	shock	shock	NOUN
bptjm-29	173	15	proteins	protein	NOUN
bptjm-29	173	16	(	(	PUNCT
bptjm-29	173	17	hsps	hsps	PROPN
bptjm-29	173	18	)	)	PUNCT
bptjm-29	173	19	which	which	PRON
bptjm-29	173	20	provide	provide	VERB
bptjm-29	173	21	neuroprotection42	neuroprotection42	NOUN
bptjm-29	173	22	.	.	PUNCT
bptjm-29	174	1	likewise	likewise	ADV
bptjm-29	174	2	,	,	PUNCT
bptjm-29	174	3	turso	turso	NOUN
bptjm-29	174	4	reduces	reduce	VERB
bptjm-29	174	5	mitochondrial	mitochondrial	ADJ
bptjm-29	174	6	stress	stress	NOUN
bptjm-29	174	7	by	by	ADP
bptjm-29	174	8	increasing	increase	VERB
bptjm-29	174	9	the	the	DET
bptjm-29	174	10	mitochondrial	mitochondrial	ADJ
bptjm-29	174	11	selectivity	selectivity	NOUN
bptjm-29	174	12	and	and	CCONJ
bptjm-29	174	13	cell	cell	NOUN
bptjm-29	174	14	's	's	PART
bptjm-29	174	15	threshold	threshold	NOUN
bptjm-29	174	16	for	for	ADP
bptjm-29	174	17	apoptosis	apoptosis	NOUN
bptjm-29	174	18	.	.	PUNCT
bptjm-29	175	1	in	in	ADP
bptjm-29	175	2	a	a	DET
bptjm-29	175	3	clinical	clinical	ADJ
bptjm-29	175	4	trial	trial	NOUN
bptjm-29	175	5	conducted	conduct	VERB
bptjm-29	175	6	by	by	ADP
bptjm-29	175	7	the	the	DET
bptjm-29	175	8	northeast	northeast	ADJ
bptjm-29	175	9	amyotrophic	amyotrophic	ADJ
bptjm-29	175	10	lateral	lateral	ADJ
bptjm-29	175	11	sclerosis	sclerosis	NOUN
bptjm-29	175	12	consortium	consortium	NOUN
bptjm-29	175	13	(	(	PUNCT
bptjm-29	175	14	neals	neal	NOUN
bptjm-29	175	15	)	)	PUNCT
bptjm-29	175	16	and	and	CCONJ
bptjm-29	175	17	amylyx	amylyx	PROPN
bptjm-29	175	18	pharmaceuticals	pharmaceutical	NOUN
bptjm-29	175	19	,	,	PUNCT
bptjm-29	175	20	patients	patient	NOUN
bptjm-29	175	21	received	receive	VERB
bptjm-29	175	22	a	a	DET
bptjm-29	175	23	2:1	2:1	NUM
bptjm-29	175	24	ratio	ratio	NOUN
bptjm-29	175	25	of	of	ADP
bptjm-29	175	26	spb	spb	PROPN
bptjm-29	175	27	to	to	ADP
bptjm-29	175	28	turso	turso	NOUN
bptjm-29	175	29	dissolved	dissolve	VERB
bptjm-29	175	30	and	and	CCONJ
bptjm-29	175	31	taken	take	VERB
bptjm-29	175	32	orally	orally	ADV
bptjm-29	175	33	or	or	CCONJ
bptjm-29	175	34	through	through	ADP
bptjm-29	175	35	a	a	DET
bptjm-29	175	36	feeding	feeding	NOUN
bptjm-29	175	37	tube	tube	NOUN
bptjm-29	175	38	.	.	PUNCT
bptjm-29	176	1	after	after	ADP
bptjm-29	176	2	the	the	DET
bptjm-29	176	3	six	six	NUM
bptjm-29	176	4	month	month	NOUN
bptjm-29	176	5	period	period	NOUN
bptjm-29	176	6	of	of	ADP
bptjm-29	176	7	daily	daily	ADJ
bptjm-29	176	8	medication	medication	NOUN
bptjm-29	176	9	,	,	PUNCT
bptjm-29	176	10	there	there	PRON
bptjm-29	176	11	was	be	VERB
bptjm-29	176	12	a	a	DET
bptjm-29	176	13	reduction	reduction	NOUN
bptjm-29	176	14	in	in	ADP
bptjm-29	176	15	the	the	DET
bptjm-29	176	16	rate	rate	NOUN
bptjm-29	176	17	of	of	ADP
bptjm-29	176	18	dysfunction	dysfunction	NOUN
bptjm-29	176	19	based	base	VERB
bptjm-29	176	20	on	on	ADP
bptjm-29	176	21	the	the	DET
bptjm-29	176	22	alsfrs	alsfrs	PROPN
bptjm-29	176	23	-	-	PUNCT
bptjm-29	176	24	r.	r.	NOUN
bptjm-29	176	25	als	als	NOUN
bptjm-29	176	26	patients	patient	NOUN
bptjm-29	176	27	involved	involve	VERB
bptjm-29	176	28	in	in	ADP
bptjm-29	176	29	this	this	DET
bptjm-29	176	30	trial	trial	NOUN
bptjm-29	176	31	were	be	AUX
bptjm-29	176	32	still	still	ADV
bptjm-29	176	33	taking	take	VERB
bptjm-29	176	34	riluzole	riluzole	NOUN
bptjm-29	176	35	,	,	PUNCT
bptjm-29	176	36	edaravone	edaravone	NOUN
bptjm-29	176	37	,	,	PUNCT
bptjm-29	176	38	or	or	CCONJ
bptjm-29	176	39	both	both	PRON
bptjm-29	176	40	,	,	PUNCT
bptjm-29	176	41	but	but	CCONJ
bptjm-29	176	42	researchers	researcher	NOUN
bptjm-29	176	43	did	do	AUX
bptjm-29	176	44	not	not	PART
bptjm-29	176	45	observe	observe	VERB
bptjm-29	176	46	notable	notable	ADJ
bptjm-29	176	47	di	di	NOUN
bptjm-29	176	48	�	�	PROPN
bptjm-29	176	49	erences	erence	NOUN
bptjm-29	176	50	in	in	ADP
bptjm-29	176	51	e	e	PROPN
bptjm-29	176	52	�	�	NOUN
bptjm-29	176	53	cacy	cacy	NOUN
bptjm-29	176	54	.	.	PUNCT
bptjm-29	177	1	in	in	ADP
bptjm-29	177	2	the	the	DET
bptjm-29	177	3	near	near	ADJ
bptjm-29	177	4	future	future	NOUN
bptjm-29	177	5	,	,	PUNCT
bptjm-29	177	6	more	more	ADJ
bptjm-29	177	7	information	information	NOUN
bptjm-29	177	8	on	on	ADP
bptjm-29	177	9	amx0035	amx0035	NOUN
bptjm-29	177	10	for	for	ADP
bptjm-29	177	11	als	als	NOUN
bptjm-29	177	12	treatment	treatment	NOUN
bptjm-29	177	13	may	may	AUX
bptjm-29	177	14	be	be	AUX
bptjm-29	177	15	obtained	obtain	VERB
bptjm-29	177	16	if	if	SCONJ
bptjm-29	177	17	it	it	PRON
bptjm-29	177	18	receives	receive	VERB
bptjm-29	177	19	fda	fda	PROPN
bptjm-29	177	20	approval	approval	NOUN
bptjm-29	177	21	and	and	CCONJ
bptjm-29	177	22	becomes	become	VERB
bptjm-29	177	23	accessible	accessible	ADJ
bptjm-29	177	24	to	to	PART
bptjm-29	177	25	als	als	VERB
bptjm-29	177	26	patients	patient	NOUN
bptjm-29	177	27	as	as	ADP
bptjm-29	177	28	a	a	DET
bptjm-29	177	29	viable	viable	ADJ
bptjm-29	177	30	option	option	NOUN
bptjm-29	177	31	alongside	alongside	ADP
bptjm-29	177	32	riluzole	riluzole	NOUN
bptjm-29	177	33	and	and	CCONJ
bptjm-29	177	34	edaravone	edaravone	NOUN
bptjm-29	177	35	.	.	PUNCT
bptjm-29	178	1	each	each	DET
bptjm-29	178	2	als	als	NOUN
bptjm-29	178	3	therapy	therapy	NOUN
bptjm-29	178	4	has	have	VERB
bptjm-29	178	5	its	its	PRON
bptjm-29	178	6	own	own	ADJ
bptjm-29	178	7	bene	bene	NOUN
bptjm-29	178	8	�	�	PROPN
bptjm-29	178	9	ts	ts	NOUN
bptjm-29	178	10	and	and	CCONJ
bptjm-29	178	11	caveats	caveat	NOUN
bptjm-29	178	12	,	,	PUNCT
bptjm-29	178	13	and	and	CCONJ
bptjm-29	178	14	due	due	ADP
bptjm-29	178	15	to	to	ADP
bptjm-29	178	16	the	the	DET
bptjm-29	178	17	diversity	diversity	NOUN
bptjm-29	178	18	in	in	ADP
bptjm-29	178	19	als	als	NOUN
bptjm-29	178	20	types	type	NOUN
bptjm-29	178	21	and	and	CCONJ
bptjm-29	178	22	als	als	NOUN
bptjm-29	178	23	patients	patient	NOUN
bptjm-29	178	24	,	,	PUNCT
bptjm-29	178	25	one	one	NUM
bptjm-29	178	26	form	form	NOUN
bptjm-29	178	27	may	may	AUX
bptjm-29	178	28	prove	prove	VERB
bptjm-29	178	29	to	to	PART
bptjm-29	178	30	be	be	AUX
bptjm-29	178	31	more	more	ADJ
bptjm-29	178	32	e	e	NOUN
bptjm-29	178	33	�	�	NOUN
bptjm-29	178	34	ective	ective	ADJ
bptjm-29	178	35	in	in	ADP
bptjm-29	178	36	reducing	reduce	VERB
bptjm-29	178	37	neurodegeneration	neurodegeneration	NOUN
bptjm-29	178	38	than	than	ADP
bptjm-29	178	39	other	other	ADJ
bptjm-29	178	40	.	.	PUNCT
bptjm-29	179	1	as	as	ADP
bptjm-29	179	2	the	the	DET
bptjm-29	179	3	�	�	PROPN
bptjm-29	179	4	rst	rst	NOUN
bptjm-29	179	5	drug	drug	NOUN
bptjm-29	179	6	for	for	ADP
bptjm-29	179	7	als	al	NOUN
bptjm-29	179	8	,	,	PUNCT
bptjm-29	179	9	riluzole	riluzole	NOUN
bptjm-29	179	10	remains	remain	VERB
bptjm-29	179	11	more	more	ADJ
bptjm-29	179	12	e	e	NOUN
bptjm-29	179	13	�	�	NOUN
bptjm-29	179	14	ective	ective	ADJ
bptjm-29	179	15	with	with	ADP
bptjm-29	179	16	extensive	extensive	ADJ
bptjm-29	179	17	results	result	NOUN
bptjm-29	179	18	from	from	ADP
bptjm-29	179	19	clinical	clinical	ADJ
bptjm-29	179	20	trials	trial	NOUN
bptjm-29	179	21	to	to	PART
bptjm-29	179	22	prove	prove	VERB
bptjm-29	179	23	its	its	PRON
bptjm-29	179	24	e	e	PROPN
bptjm-29	179	25	�	�	NOUN
bptjm-29	179	26	cacy	cacy	NOUN
bptjm-29	179	27	.	.	PUNCT
bptjm-29	180	1	advancements	advancement	NOUN
bptjm-29	180	2	in	in	ADP
bptjm-29	180	3	the	the	DET
bptjm-29	180	4	development	development	NOUN
bptjm-29	180	5	of	of	ADP
bptjm-29	180	6	newer	new	ADJ
bptjm-29	180	7	drugs	drug	NOUN
bptjm-29	180	8	such	such	ADJ
bptjm-29	180	9	as	as	ADP
bptjm-29	180	10	edaravone	edaravone	NOUN
bptjm-29	180	11	and	and	CCONJ
bptjm-29	180	12	amx0035	amx0035	NOUN
bptjm-29	180	13	provide	provide	VERB
bptjm-29	180	14	increased	increase	VERB
bptjm-29	180	15	con	con	PROPN
bptjm-29	180	16	�	�	PROPN
bptjm-29	180	17	dence	dence	NOUN
bptjm-29	180	18	in	in	ADP
bptjm-29	180	19	the	the	DET
bptjm-29	180	20	possibility	possibility	NOUN
bptjm-29	180	21	of	of	ADP
bptjm-29	180	22	slowing	slow	VERB
bptjm-29	180	23	the	the	DET
bptjm-29	180	24	rate	rate	NOUN
bptjm-29	180	25	of	of	ADP
bptjm-29	180	26	als	als	NOUN
bptjm-29	180	27	progression	progression	NOUN
bptjm-29	180	28	.	.	PUNCT
bptjm-29	181	1	similarly	similarly	ADV
bptjm-29	181	2	,	,	PUNCT
bptjm-29	181	3	stakeholders	stakeholder	NOUN
bptjm-29	181	4	are	be	AUX
bptjm-29	181	5	increasingly	increasingly	ADV
bptjm-29	181	6	interested	interested	ADJ
bptjm-29	181	7	in	in	ADP
bptjm-29	181	8	new	new	ADJ
bptjm-29	181	9	therapies	therapy	NOUN
bptjm-29	181	10	for	for	ADP
bptjm-29	181	11	increased	increase	VERB
bptjm-29	181	12	access	access	NOUN
bptjm-29	181	13	and	and	CCONJ
bptjm-29	181	14	improvements	improvement	NOUN
bptjm-29	181	15	on	on	ADP
bptjm-29	181	16	the	the	DET
bptjm-29	181	17	als	als	NOUN
bptjm-29	181	18	rating	rating	NOUN
bptjm-29	181	19	scale	scale	NOUN
bptjm-29	181	20	.	.	PUNCT
bptjm-29	182	1	while	while	SCONJ
bptjm-29	182	2	none	none	NOUN
bptjm-29	182	3	of	of	ADP
bptjm-29	182	4	the	the	DET
bptjm-29	182	5	drugs	drug	NOUN
bptjm-29	182	6	approved	approve	VERB
bptjm-29	182	7	for	for	ADP
bptjm-29	182	8	als	al	NOUN
bptjm-29	182	9	are	be	AUX
bptjm-29	182	10	a	a	DET
bptjm-29	182	11	complete	complete	ADJ
bptjm-29	182	12	cure	cure	NOUN
bptjm-29	182	13	because	because	SCONJ
bptjm-29	182	14	they	they	PRON
bptjm-29	182	15	solely	solely	ADV
bptjm-29	182	16	function	function	VERB
bptjm-29	182	17	to	to	PART
bptjm-29	182	18	delay	delay	VERB
bptjm-29	182	19	disease	disease	NOUN
bptjm-29	182	20	propagation	propagation	NOUN
bptjm-29	182	21	,	,	PUNCT
bptjm-29	182	22	new	new	ADJ
bptjm-29	182	23	approaches	approach	NOUN
bptjm-29	182	24	are	be	AUX
bptjm-29	182	25	still	still	ADV
bptjm-29	182	26	being	be	AUX
bptjm-29	182	27	tested	test	VERB
bptjm-29	182	28	for	for	ADP
bptjm-29	182	29	factors	factor	NOUN
bptjm-29	182	30	including	include	VERB
bptjm-29	182	31	an	an	DET
bptjm-29	182	32	increase	increase	NOUN
bptjm-29	182	33	in	in	ADP
bptjm-29	182	34	survival	survival	NOUN
bptjm-29	182	35	probability	probability	NOUN
bptjm-29	182	36	,	,	PUNCT
bptjm-29	182	37	safety	safety	NOUN
bptjm-29	182	38	,	,	PUNCT
bptjm-29	182	39	and	and	CCONJ
bptjm-29	182	40	long	long	ADJ
bptjm-29	182	41	-	-	PUNCT
bptjm-29	182	42	term	term	NOUN
bptjm-29	182	43	consequences	consequence	NOUN
bptjm-29	182	44	,	,	PUNCT
bptjm-29	182	45	riluzole	riluzole	NOUN
bptjm-29	182	46	still	still	ADV
bptjm-29	182	47	remains	remain	VERB
bptjm-29	182	48	the	the	DET
bptjm-29	182	49	most	most	ADV
bptjm-29	182	50	prevalent	prevalent	ADJ
bptjm-29	182	51	treatment	treatment	NOUN
bptjm-29	182	52	.	.	PUNCT
bptjm-29	183	1	berkeley	berkeley	PROPN
bptjm-29	183	2	pharma	pharma	PROPN
bptjm-29	183	3	tech	tech	PROPN
bptjm-29	183	4	journal	journal	NOUN
bptjm-29	183	5	of	of	ADP
bptjm-29	183	6	medicine	medicine	NOUN
bptjm-29	183	7	|	|	ADV
bptjm-29	183	8	81	81	NUM
bptjm-29	183	9	https://www.zotero.org/google-docs/?koqact	https://www.zotero.org/google-docs/?koqact	NOUN
bptjm-29	183	10	table	table	NOUN
bptjm-29	183	11	1	1	NUM
bptjm-29	183	12	.	.	PUNCT
bptjm-29	184	1	a	a	DET
bptjm-29	184	2	comparison	comparison	NOUN
bptjm-29	184	3	table	table	NOUN
bptjm-29	184	4	of	of	ADP
bptjm-29	184	5	the	the	DET
bptjm-29	184	6	drugs	drug	NOUN
bptjm-29	184	7	riluzole	riluzole	NOUN
bptjm-29	184	8	,	,	PUNCT
bptjm-29	184	9	edaravone	edaravone	NOUN
bptjm-29	184	10	,	,	PUNCT
bptjm-29	184	11	and	and	CCONJ
bptjm-29	184	12	amx0035	amx0035	VERB
bptjm-29	184	13	for	for	ADP
bptjm-29	184	14	als	als	NOUN
bptjm-29	184	15	4	4	NUM
bptjm-29	184	16	.	.	PUNCT
bptjm-29	184	17	gene	gene	NOUN
bptjm-29	184	18	therapy	therapy	NOUN
bptjm-29	184	19	since	since	SCONJ
bptjm-29	184	20	pharmacological	pharmacological	ADJ
bptjm-29	184	21	therapeutics	therapeutic	NOUN
bptjm-29	184	22	have	have	VERB
bptjm-29	184	23	yet	yet	ADV
bptjm-29	184	24	to	to	PART
bptjm-29	184	25	eradicate	eradicate	VERB
bptjm-29	184	26	and	and	CCONJ
bptjm-29	184	27	cure	cure	NOUN
bptjm-29	184	28	als	al	NOUN
bptjm-29	184	29	,	,	PUNCT
bptjm-29	184	30	gene	gene	NOUN
bptjm-29	184	31	therapy	therapy	NOUN
bptjm-29	184	32	approaches	approach	NOUN
bptjm-29	184	33	have	have	AUX
bptjm-29	184	34	also	also	ADV
bptjm-29	184	35	been	be	AUX
bptjm-29	184	36	explored	explore	VERB
bptjm-29	184	37	as	as	ADP
bptjm-29	184	38	a	a	DET
bptjm-29	184	39	potential	potential	ADJ
bptjm-29	184	40	solution	solution	NOUN
bptjm-29	184	41	.	.	PUNCT
bptjm-29	185	1	gene	gene	NOUN
bptjm-29	185	2	therapy	therapy	NOUN
bptjm-29	185	3	can	can	AUX
bptjm-29	185	4	be	be	AUX
bptjm-29	185	5	divided	divide	VERB
bptjm-29	185	6	into	into	ADP
bptjm-29	185	7	two	two	NUM
bptjm-29	185	8	types	type	NOUN
bptjm-29	185	9	:	:	PUNCT
bptjm-29	185	10	(	(	PUNCT
bptjm-29	185	11	1	1	X
bptjm-29	185	12	)	)	PUNCT
bptjm-29	185	13	non	non	ADJ
bptjm-29	185	14	-	-	ADJ
bptjm-29	185	15	viral	viral	ADJ
bptjm-29	185	16	gene	gene	NOUN
bptjm-29	185	17	therapy	therapy	NOUN
bptjm-29	185	18	where	where	SCONJ
bptjm-29	185	19	nucleic	nucleic	ADJ
bptjm-29	185	20	acid	acid	NOUN
bptjm-29	185	21	sequences	sequence	NOUN
bptjm-29	185	22	are	be	AUX
bptjm-29	185	23	delivered	deliver	VERB
bptjm-29	185	24	to	to	ADP
bptjm-29	185	25	the	the	DET
bptjm-29	185	26	host	host	NOUN
bptjm-29	185	27	cell	cell	NOUN
bptjm-29	185	28	for	for	ADP
bptjm-29	185	29	pathological	pathological	ADJ
bptjm-29	185	30	modi	modi	PROPN
bptjm-29	185	31	�	�	PROPN
bptjm-29	185	32	cation	cation	NOUN
bptjm-29	185	33	;	;	PUNCT
bptjm-29	185	34	and	and	CCONJ
bptjm-29	185	35	(	(	PUNCT
bptjm-29	185	36	2	2	X
bptjm-29	185	37	)	)	PUNCT
bptjm-29	185	38	viral	viral	ADJ
bptjm-29	185	39	gene	gene	NOUN
bptjm-29	185	40	therapy	therapy	NOUN
bptjm-29	185	41	in	in	ADP
bptjm-29	185	42	which	which	PRON
bptjm-29	185	43	genetically	genetically	ADV
bptjm-29	185	44	-	-	PUNCT
bptjm-29	185	45	modi	modi	PROPN
bptjm-29	185	46	�	�	PROPN
bptjm-29	185	47	ed	ed	PROPN
bptjm-29	185	48	viruses	virus	NOUN
bptjm-29	185	49	are	be	AUX
bptjm-29	185	50	used	use	VERB
bptjm-29	185	51	as	as	ADP
bptjm-29	185	52	viral	viral	ADJ
bptjm-29	185	53	vectors	vector	NOUN
bptjm-29	185	54	to	to	PART
bptjm-29	185	55	deliver	deliver	VERB
bptjm-29	185	56	sequences	sequence	NOUN
bptjm-29	185	57	.	.	PUNCT
bptjm-29	186	1	antisense	antisense	NOUN
bptjm-29	186	2	oligonucleotide	oligonucleotide	NOUN
bptjm-29	186	3	(	(	PUNCT
bptjm-29	186	4	aso	aso	NOUN
bptjm-29	186	5	)	)	PUNCT
bptjm-29	186	6	drugs	drug	NOUN
bptjm-29	186	7	belong	belong	VERB
bptjm-29	186	8	to	to	ADP
bptjm-29	186	9	category	category	NOUN
bptjm-29	186	10	one	one	NUM
bptjm-29	186	11	and	and	CCONJ
bptjm-29	186	12	are	be	AUX
bptjm-29	186	13	used	use	VERB
bptjm-29	186	14	in	in	ADP
bptjm-29	186	15	pre	pre	ADJ
bptjm-29	186	16	-	-	ADJ
bptjm-29	186	17	clinical	clinical	ADJ
bptjm-29	186	18	trials	trial	NOUN
bptjm-29	186	19	of	of	ADP
bptjm-29	186	20	sod1	sod1	NOUN
bptjm-29	186	21	-	-	PUNCT
bptjm-29	186	22	fals	fal	NOUN
bptjm-29	186	23	.	.	PUNCT
bptjm-29	187	1	superoxide	superoxide	NOUN
bptjm-29	187	2	dismutase	dismutase	NOUN
bptjm-29	187	3	1	1	NUM
bptjm-29	187	4	(	(	PUNCT
bptjm-29	187	5	sod1	sod1	NOUN
bptjm-29	187	6	)	)	PUNCT
bptjm-29	187	7	is	be	AUX
bptjm-29	187	8	the	the	DET
bptjm-29	187	9	�	�	PROPN
bptjm-29	187	10	rst	rst	PROPN
bptjm-29	187	11	of	of	ADP
bptjm-29	187	12	30	30	NUM
bptjm-29	187	13	als	als	ADV
bptjm-29	187	14	-	-	PUNCT
bptjm-29	187	15	related	relate	VERB
bptjm-29	187	16	genes	gene	NOUN
bptjm-29	187	17	currently	currently	ADV
bptjm-29	187	18	discovered	discover	VERB
bptjm-29	187	19	.	.	PUNCT
bptjm-29	188	1	oxidative	oxidative	ADJ
bptjm-29	188	2	damage	damage	NOUN
bptjm-29	188	3	is	be	AUX
bptjm-29	188	4	a	a	DET
bptjm-29	188	5	result	result	NOUN
bptjm-29	188	6	of	of	ADP
bptjm-29	188	7	an	an	DET
bptjm-29	188	8	abundance	abundance	NOUN
bptjm-29	188	9	of	of	ADP
bptjm-29	188	10	ros	ros	PROPN
bptjm-29	188	11	such	such	ADJ
bptjm-29	188	12	as	as	ADP
bptjm-29	188	13	superoxide	superoxide	NOUN
bptjm-29	188	14	in	in	ADP
bptjm-29	188	15	the	the	DET
bptjm-29	188	16	cell	cell	NOUN
bptjm-29	188	17	,	,	PUNCT
bptjm-29	188	18	making	make	VERB
bptjm-29	188	19	it	it	PRON
bptjm-29	188	20	unable	unable	ADJ
bptjm-29	188	21	to	to	PART
bptjm-29	188	22	prevent	prevent	VERB
bptjm-29	188	23	cellular	cellular	ADJ
bptjm-29	188	24	stress	stress	NOUN
bptjm-29	188	25	.	.	PUNCT
bptjm-29	189	1	sod1	sod1	ADJ
bptjm-29	189	2	prevents	prevent	VERB
bptjm-29	189	3	oxidative	oxidative	ADJ
bptjm-29	189	4	damage	damage	NOUN
bptjm-29	189	5	and	and	CCONJ
bptjm-29	189	6	reduces	reduce	VERB
bptjm-29	189	7	superoxide	superoxide	NOUN
bptjm-29	189	8	leakage	leakage	NOUN
bptjm-29	189	9	from	from	ADP
bptjm-29	189	10	mitochondria	mitochondria	NOUN
bptjm-29	189	11	by	by	ADP
bptjm-29	189	12	catalyzing	catalyze	VERB
bptjm-29	189	13	the	the	DET
bptjm-29	189	14	conversion	conversion	NOUN
bptjm-29	189	15	of	of	ADP
bptjm-29	189	16	superoxide	superoxide	NOUN
bptjm-29	189	17	into	into	ADP
bptjm-29	189	18	oxygen	oxygen	NOUN
bptjm-29	189	19	and	and	CCONJ
bptjm-29	189	20	hydrogen	hydrogen	NOUN
bptjm-29	189	21	peroxide	peroxide	NOUN
bptjm-29	189	22	.	.	PUNCT
bptjm-29	190	1	mutations	mutation	NOUN
bptjm-29	190	2	in	in	ADP
bptjm-29	190	3	the	the	DET
bptjm-29	190	4	sod1	sod1	ADJ
bptjm-29	190	5	gene	gene	NOUN
bptjm-29	190	6	contribute	contribute	VERB
bptjm-29	190	7	to	to	ADP
bptjm-29	190	8	the	the	DET
bptjm-29	190	9	pathogenesis	pathogenesis	NOUN
bptjm-29	190	10	of	of	ADP
bptjm-29	190	11	familial	familial	ADJ
bptjm-29	190	12	als	al	NOUN
bptjm-29	190	13	and	and	CCONJ
bptjm-29	190	14	accounts	account	VERB
bptjm-29	190	15	for	for	ADP
bptjm-29	190	16	15–20	15–20	NUM
bptjm-29	190	17	%	%	NOUN
bptjm-29	190	18	of	of	ADP
bptjm-29	190	19	fals	fal	NOUN
bptjm-29	190	20	cases	case	NOUN
bptjm-29	190	21	,	,	PUNCT
bptjm-29	190	22	and	and	CCONJ
bptjm-29	190	23	begin	begin	VERB
bptjm-29	190	24	with	with	ADP
bptjm-29	190	25	the	the	DET
bptjm-29	190	26	misfolding	misfolding	NOUN
bptjm-29	190	27	of	of	ADP
bptjm-29	190	28	the	the	DET
bptjm-29	190	29	gene	gene	NOUN
bptjm-29	190	30	which	which	PRON
bptjm-29	190	31	causes	cause	VERB
bptjm-29	190	32	it	it	PRON
bptjm-29	190	33	to	to	PART
bptjm-29	190	34	be	be	AUX
bptjm-29	190	35	degraded	degrade	VERB
bptjm-29	190	36	by	by	ADP
bptjm-29	190	37	the	the	DET
bptjm-29	190	38	ubiquitin	ubiquitin	ADJ
bptjm-29	190	39	/	/	SYM
bptjm-29	190	40	proteasome	proteasome	NOUN
bptjm-29	190	41	system	system	NOUN
bptjm-29	190	42	(	(	PUNCT
bptjm-29	190	43	ups)18	ups)18	ADV
bptjm-29	190	44	.	.	PUNCT
bptjm-29	191	1	however	however	ADV
bptjm-29	191	2	,	,	PUNCT
bptjm-29	191	3	once	once	ADV
bptjm-29	191	4	a	a	DET
bptjm-29	191	5	large	large	ADJ
bptjm-29	191	6	concentration	concentration	NOUN
bptjm-29	191	7	of	of	ADP
bptjm-29	191	8	misfolded	misfolded	ADJ
bptjm-29	191	9	proteins	protein	NOUN
bptjm-29	191	10	accumulate	accumulate	VERB
bptjm-29	191	11	,	,	PUNCT
bptjm-29	191	12	this	this	DET
bptjm-29	191	13	disrupts	disrupt	NOUN
bptjm-29	191	14	proteostasis	proteostasis	NOUN
bptjm-29	191	15	–	–	PUNCT
bptjm-29	191	16	the	the	DET
bptjm-29	191	17	regulation	regulation	NOUN
bptjm-29	191	18	of	of	ADP
bptjm-29	191	19	proteins	protein	NOUN
bptjm-29	191	20	from	from	ADP
bptjm-29	191	21	synthesis	synthesis	NOUN
bptjm-29	191	22	to	to	ADP
bptjm-29	191	23	degradation	degradation	NOUN
bptjm-29	191	24	–	–	PUNCT
bptjm-29	191	25	and	and	CCONJ
bptjm-29	191	26	retriggers	retrigger	NOUN
bptjm-29	191	27	autophagocytosis	autophagocytosis	VERB
bptjm-29	191	28	to	to	PART
bptjm-29	191	29	increase	increase	VERB
bptjm-29	191	30	the	the	DET
bptjm-29	191	31	number	number	NOUN
bptjm-29	191	32	of	of	ADP
bptjm-29	191	33	autophagosomes	autophagosome	NOUN
bptjm-29	191	34	for	for	ADP
bptjm-29	191	35	the	the	DET
bptjm-29	191	36	removal	removal	NOUN
bptjm-29	191	37	of	of	ADP
bptjm-29	191	38	dysfunctional	dysfunctional	ADJ
bptjm-29	191	39	cellular	cellular	ADJ
bptjm-29	191	40	constituents16	constituents16	NOUN
bptjm-29	191	41	.	.	PUNCT
bptjm-29	192	1	over	over	ADP
bptjm-29	192	2	time	time	NOUN
bptjm-29	192	3	,	,	PUNCT
bptjm-29	192	4	an	an	DET
bptjm-29	192	5	accumulation	accumulation	NOUN
bptjm-29	192	6	of	of	ADP
bptjm-29	192	7	mutated	mutate	VERB
bptjm-29	192	8	sod1	sod1	ADJ
bptjm-29	192	9	proteins	protein	NOUN
bptjm-29	192	10	induces	induce	VERB
bptjm-29	192	11	cell	cell	NOUN
bptjm-29	192	12	stress	stress	NOUN
bptjm-29	192	13	responses	response	NOUN
bptjm-29	192	14	,	,	PUNCT
bptjm-29	192	15	resulting	result	VERB
bptjm-29	192	16	in	in	ADP
bptjm-29	192	17	disease	disease	NOUN
bptjm-29	192	18	pathogenesis	pathogenesis	NOUN
bptjm-29	192	19	.	.	PUNCT
bptjm-29	193	1	a	a	DET
bptjm-29	193	2	buildup	buildup	NOUN
bptjm-29	193	3	of	of	ADP
bptjm-29	193	4	misfolded	misfolded	ADJ
bptjm-29	193	5	mutant	mutant	ADJ
bptjm-29	193	6	sod1	sod1	ADJ
bptjm-29	193	7	proteins	protein	NOUN
bptjm-29	193	8	in	in	ADP
bptjm-29	193	9	the	the	DET
bptjm-29	193	10	mitochondria	mitochondria	NOUN
bptjm-29	193	11	can	can	AUX
bptjm-29	193	12	adversely	adversely	ADV
bptjm-29	193	13	a	a	DET
bptjm-29	193	14	�	�	NOUN
bptjm-29	193	15	ect	ect	ADJ
bptjm-29	193	16	physiological	physiological	ADJ
bptjm-29	193	17	function	function	NOUN
bptjm-29	193	18	of	of	ADP
bptjm-29	193	19	the	the	DET
bptjm-29	193	20	organelle	organelle	NOUN
bptjm-29	193	21	.	.	PUNCT
bptjm-29	194	1	speci	speci	PROPN
bptjm-29	194	2	�	�	PROPN
bptjm-29	194	3	cally	cally	ADV
bptjm-29	194	4	,	,	PUNCT
bptjm-29	194	5	studies	study	NOUN
bptjm-29	194	6	have	have	AUX
bptjm-29	194	7	noted	note	VERB
bptjm-29	194	8	irregularities	irregularity	NOUN
bptjm-29	194	9	in	in	ADP
bptjm-29	194	10	the	the	DET
bptjm-29	194	11	berkeley	berkeley	PROPN
bptjm-29	194	12	pharma	pharma	PROPN
bptjm-29	194	13	tech	tech	NOUN
bptjm-29	194	14	journal	journal	NOUN
bptjm-29	194	15	of	of	ADP
bptjm-29	194	16	medicine	medicine	NOUN
bptjm-29	195	1	|	|	ADV
bptjm-29	195	2	82	82	NUM
bptjm-29	195	3	https://www.zotero.org/google-docs/?bokk7b	https://www.zotero.org/google-docs/?bokk7b	NOUN
bptjm-29	195	4	https://www.zotero.org/google-docs/?3w43hl	https://www.zotero.org/google-docs/?3w43hl	NOUN
bptjm-29	195	5	production	production	NOUN
bptjm-29	195	6	of	of	ADP
bptjm-29	195	7	atp	atp	PROPN
bptjm-29	195	8	and	and	CCONJ
bptjm-29	195	9	ros	ros	PROPN
bptjm-29	195	10	which	which	PRON
bptjm-29	195	11	signal	signal	VERB
bptjm-29	195	12	cell	cell	NOUN
bptjm-29	195	13	survival	survival	NOUN
bptjm-29	195	14	and	and	CCONJ
bptjm-29	195	15	cell	cell	NOUN
bptjm-29	195	16	death	death	NOUN
bptjm-29	195	17	,	,	PUNCT
bptjm-29	195	18	energy	energy	NOUN
bptjm-29	195	19	and	and	CCONJ
bptjm-29	195	20	calcium	calcium	NOUN
bptjm-29	195	21	homeostasis	homeostasis	NOUN
bptjm-29	195	22	,	,	PUNCT
bptjm-29	195	23	and	and	CCONJ
bptjm-29	195	24	apoptosis	apoptosis	NOUN
bptjm-29	195	25	in	in	ADP
bptjm-29	195	26	mitochondrial	mitochondrial	ADJ
bptjm-29	195	27	transport	transport	NOUN
bptjm-29	195	28	along	along	ADP
bptjm-29	195	29	axons9	axons9	PROPN
bptjm-29	195	30	.	.	PUNCT
bptjm-29	196	1	an	an	DET
bptjm-29	196	2	aso	aso	NOUN
bptjm-29	196	3	used	use	VERB
bptjm-29	196	4	to	to	PART
bptjm-29	196	5	target	target	VERB
bptjm-29	196	6	sod1	sod1	ADJ
bptjm-29	196	7	mrna	mrna	NOUN
bptjm-29	196	8	is	be	AUX
bptjm-29	196	9	tofersen	tofersen	VERB
bptjm-29	196	10	(	(	PUNCT
bptjm-29	196	11	biib067	biib067	PROPN
bptjm-29	196	12	)	)	PUNCT
bptjm-29	196	13	,	,	PUNCT
bptjm-29	196	14	previously	previously	ADV
bptjm-29	196	15	‘	'	PUNCT
bptjm-29	196	16	ionis	ionis	NOUN
bptjm-29	196	17	-	-	PUNCT
bptjm-29	196	18	sod1rx	sod1rx	PROPN
bptjm-29	196	19	.	.	PUNCT
bptjm-29	196	20	’	'	PUNCT
bptjm-29	197	1	it	it	PRON
bptjm-29	197	2	relies	rely	VERB
bptjm-29	197	3	on	on	ADP
bptjm-29	197	4	ribonuclease	ribonuclease	NOUN
bptjm-29	197	5	h	h	NOUN
bptjm-29	197	6	(	(	PUNCT
bptjm-29	197	7	rnase	rnase	PROPN
bptjm-29	197	8	h	h	PROPN
bptjm-29	197	9	)	)	PUNCT
bptjm-29	197	10	,	,	PUNCT
bptjm-29	197	11	an	an	DET
bptjm-29	197	12	endoribonuclease	endoribonuclease	NOUN
bptjm-29	197	13	enzyme	enzyme	NOUN
bptjm-29	197	14	that	that	PRON
bptjm-29	197	15	cleaves	cleave	VERB
bptjm-29	197	16	the	the	DET
bptjm-29	197	17	rna	rna	NOUN
bptjm-29	197	18	from	from	ADP
bptjm-29	197	19	the	the	DET
bptjm-29	197	20	rna	rna	PROPN
bptjm-29	197	21	/	/	SYM
bptjm-29	197	22	dna	dna	PROPN
bptjm-29	197	23	hybrid	hybrid	NOUN
bptjm-29	197	24	,	,	PUNCT
bptjm-29	197	25	to	to	PART
bptjm-29	197	26	degrade	degrade	VERB
bptjm-29	197	27	sod1	sod1	ADJ
bptjm-29	197	28	mrna	mrna	NOUN
bptjm-29	197	29	and	and	CCONJ
bptjm-29	197	30	prevent	prevent	VERB
bptjm-29	197	31	the	the	DET
bptjm-29	197	32	production	production	NOUN
bptjm-29	197	33	of	of	ADP
bptjm-29	197	34	toxic	toxic	ADJ
bptjm-29	197	35	sod1	sod1	ADJ
bptjm-29	197	36	proteins18	proteins18	NOUN
bptjm-29	197	37	.	.	PUNCT
bptjm-29	198	1	in	in	ADP
bptjm-29	198	2	a	a	DET
bptjm-29	198	3	phase	phase	NOUN
bptjm-29	198	4	1/2	1/2	NUM
bptjm-29	198	5	clinical	clinical	ADJ
bptjm-29	198	6	trial	trial	NOUN
bptjm-29	198	7	,	,	PUNCT
bptjm-29	198	8	als	als	VERB
bptjm-29	198	9	patients	patient	NOUN
bptjm-29	198	10	with	with	ADP
bptjm-29	198	11	a	a	DET
bptjm-29	198	12	sod1	sod1	ADJ
bptjm-29	198	13	mutation	mutation	NOUN
bptjm-29	198	14	received	receive	VERB
bptjm-29	198	15	multiple	multiple	ADJ
bptjm-29	198	16	doses	dose	NOUN
bptjm-29	198	17	of	of	ADP
bptjm-29	198	18	tofersen	tofersen	NOUN
bptjm-29	198	19	,	,	PUNCT
bptjm-29	198	20	and	and	CCONJ
bptjm-29	198	21	results	result	NOUN
bptjm-29	198	22	showed	show	VERB
bptjm-29	198	23	that	that	SCONJ
bptjm-29	198	24	patients	patient	NOUN
bptjm-29	198	25	treated	treat	VERB
bptjm-29	198	26	with	with	ADP
bptjm-29	198	27	the	the	DET
bptjm-29	198	28	greatest	great	ADJ
bptjm-29	198	29	concentration	concentration	NOUN
bptjm-29	198	30	of	of	ADP
bptjm-29	198	31	the	the	DET
bptjm-29	198	32	aso	aso	NOUN
bptjm-29	198	33	had	have	VERB
bptjm-29	198	34	lower	low	ADJ
bptjm-29	198	35	sod1	sod1	ADJ
bptjm-29	198	36	protein	protein	NOUN
bptjm-29	198	37	levels	level	NOUN
bptjm-29	198	38	by	by	ADP
bptjm-29	198	39	36	36	NUM
bptjm-29	198	40	%	%	NOUN
bptjm-29	198	41	.	.	PUNCT
bptjm-29	199	1	also	also	ADV
bptjm-29	199	2	,	,	PUNCT
bptjm-29	199	3	a	a	DET
bptjm-29	199	4	decline	decline	NOUN
bptjm-29	199	5	in	in	ADP
bptjm-29	199	6	the	the	DET
bptjm-29	199	7	reduction	reduction	NOUN
bptjm-29	199	8	in	in	ADP
bptjm-29	199	9	the	the	DET
bptjm-29	199	10	alsfrs	alsfrs	NOUN
bptjm-29	199	11	-	-	PUNCT
bptjm-29	199	12	r	r	NOUN
bptjm-29	199	13	score	score	NOUN
bptjm-29	199	14	was	be	AUX
bptjm-29	199	15	observed	observe	VERB
bptjm-29	199	16	.	.	PUNCT
bptjm-29	200	1	however	however	ADV
bptjm-29	200	2	,	,	PUNCT
bptjm-29	200	3	since	since	SCONJ
bptjm-29	200	4	the	the	DET
bptjm-29	200	5	drug	drug	NOUN
bptjm-29	200	6	was	be	AUX
bptjm-29	200	7	delivered	deliver	VERB
bptjm-29	200	8	via	via	ADP
bptjm-29	200	9	an	an	DET
bptjm-29	200	10	intrathecal	intrathecal	ADJ
bptjm-29	200	11	lumbar	lumbar	NOUN
bptjm-29	200	12	puncture	puncture	NOUN
bptjm-29	200	13	,	,	PUNCT
bptjm-29	200	14	adverse	adverse	ADJ
bptjm-29	200	15	e	e	NOUN
bptjm-29	200	16	�	�	NOUN
bptjm-29	200	17	ects	ect	NOUN
bptjm-29	200	18	including	include	VERB
bptjm-29	200	19	headache	headache	NOUN
bptjm-29	200	20	and	and	CCONJ
bptjm-29	200	21	back	back	ADJ
bptjm-29	200	22	pain	pain	NOUN
bptjm-29	200	23	were	be	AUX
bptjm-29	200	24	common	common	ADJ
bptjm-29	200	25	consequences	consequence	NOUN
bptjm-29	200	26	.	.	PUNCT
bptjm-29	201	1	in	in	ADP
bptjm-29	201	2	another	another	DET
bptjm-29	201	3	approach	approach	NOUN
bptjm-29	201	4	,	,	PUNCT
bptjm-29	201	5	researchers	researcher	NOUN
bptjm-29	201	6	relied	rely	VERB
bptjm-29	201	7	on	on	ADP
bptjm-29	201	8	a	a	DET
bptjm-29	201	9	lentivirus	lentivirus	NOUN
bptjm-29	201	10	encoding	encoding	NOUN
bptjm-29	201	11	for	for	ADP
bptjm-29	201	12	an	an	DET
bptjm-29	201	13	rna	rna	NOUN
bptjm-29	201	14	silencing	silence	VERB
bptjm-29	201	15	(	(	PUNCT
bptjm-29	201	16	sirna	sirna	PROPN
bptjm-29	201	17	)	)	PUNCT
bptjm-29	201	18	gene	gene	NOUN
bptjm-29	201	19	that	that	PRON
bptjm-29	201	20	catalyzes	catalyze	VERB
bptjm-29	201	21	the	the	DET
bptjm-29	201	22	selective	selective	ADJ
bptjm-29	201	23	degradation	degradation	NOUN
bptjm-29	201	24	of	of	ADP
bptjm-29	201	25	sod1	sod1	NOUN
bptjm-29	201	26	-	-	PUNCT
bptjm-29	201	27	mrna	mrna	NOUN
bptjm-29	201	28	.	.	PUNCT
bptjm-29	202	1	the	the	DET
bptjm-29	202	2	injection	injection	NOUN
bptjm-29	202	3	of	of	ADP
bptjm-29	202	4	this	this	DET
bptjm-29	202	5	virus	virus	NOUN
bptjm-29	202	6	in	in	ADP
bptjm-29	202	7	the	the	DET
bptjm-29	202	8	muscle	muscle	NOUN
bptjm-29	202	9	or	or	CCONJ
bptjm-29	202	10	directly	directly	ADV
bptjm-29	202	11	in	in	ADP
bptjm-29	202	12	the	the	DET
bptjm-29	202	13	spinal	spinal	ADJ
bptjm-29	202	14	cord	cord	NOUN
bptjm-29	202	15	of	of	ADP
bptjm-29	202	16	transgenic	transgenic	NOUN
bptjm-29	202	17	mouse	mouse	NOUN
bptjm-29	202	18	models	model	NOUN
bptjm-29	202	19	of	of	ADP
bptjm-29	202	20	als	al	NOUN
bptjm-29	202	21	showed	show	VERB
bptjm-29	202	22	reduced	reduce	VERB
bptjm-29	202	23	sod1	sod1	ADJ
bptjm-29	202	24	expression	expression	NOUN
bptjm-29	202	25	delaying	delay	VERB
bptjm-29	202	26	the	the	DET
bptjm-29	202	27	neurodegeneration	neurodegeneration	NOUN
bptjm-29	202	28	,	,	PUNCT
bptjm-29	202	29	but	but	CCONJ
bptjm-29	202	30	data	datum	NOUN
bptjm-29	202	31	about	about	ADP
bptjm-29	202	32	the	the	DET
bptjm-29	202	33	slowing	slowing	NOUN
bptjm-29	202	34	down	down	ADP
bptjm-29	202	35	of	of	ADP
bptjm-29	202	36	the	the	DET
bptjm-29	202	37	disease	disease	NOUN
bptjm-29	202	38	progression	progression	NOUN
bptjm-29	202	39	and	and	CCONJ
bptjm-29	202	40	survival	survival	NOUN
bptjm-29	202	41	is	be	AUX
bptjm-29	202	42	controversial	controversial	ADJ
bptjm-29	202	43	and	and	CCONJ
bptjm-29	202	44	requires	require	VERB
bptjm-29	202	45	further	further	ADJ
bptjm-29	202	46	study9	study9	NOUN
bptjm-29	202	47	.	.	PUNCT
bptjm-29	203	1	gene	gene	NOUN
bptjm-29	203	2	therapy	therapy	NOUN
bptjm-29	203	3	targeting	target	VERB
bptjm-29	203	4	the	the	DET
bptjm-29	203	5	many	many	ADJ
bptjm-29	203	6	als	als	ADV
bptjm-29	203	7	-	-	PUNCT
bptjm-29	203	8	related	relate	VERB
bptjm-29	203	9	genes	gene	NOUN
bptjm-29	203	10	can	can	AUX
bptjm-29	203	11	prevent	prevent	VERB
bptjm-29	203	12	disease	disease	NOUN
bptjm-29	203	13	proliferation	proliferation	NOUN
bptjm-29	203	14	by	by	ADP
bptjm-29	203	15	directly	directly	ADV
bptjm-29	203	16	preventing	prevent	VERB
bptjm-29	203	17	mutations	mutation	NOUN
bptjm-29	203	18	at	at	ADP
bptjm-29	203	19	the	the	DET
bptjm-29	203	20	source	source	NOUN
bptjm-29	203	21	.	.	PUNCT
bptjm-29	204	1	sod1	sod1	ADJ
bptjm-29	204	2	mutations	mutation	NOUN
bptjm-29	204	3	can	can	AUX
bptjm-29	204	4	lead	lead	VERB
bptjm-29	204	5	to	to	ADP
bptjm-29	204	6	excitotoxicity	excitotoxicity	NOUN
bptjm-29	204	7	,	,	PUNCT
bptjm-29	204	8	mitochondrial	mitochondrial	ADJ
bptjm-29	204	9	dysfunction	dysfunction	NOUN
bptjm-29	204	10	,	,	PUNCT
bptjm-29	204	11	and	and	CCONJ
bptjm-29	204	12	er	er	INTJ
bptjm-29	204	13	stress	stress	NOUN
bptjm-29	204	14	which	which	PRON
bptjm-29	204	15	increases	increase	VERB
bptjm-29	204	16	the	the	DET
bptjm-29	204	17	likeliness	likeliness	NOUN
bptjm-29	204	18	of	of	ADP
bptjm-29	204	19	motor	motor	NOUN
bptjm-29	204	20	neuron	neuron	PROPN
bptjm-29	204	21	degeneration	degeneration	NOUN
bptjm-29	204	22	.	.	PUNCT
bptjm-29	205	1	the	the	DET
bptjm-29	205	2	appeal	appeal	NOUN
bptjm-29	205	3	of	of	ADP
bptjm-29	205	4	this	this	DET
bptjm-29	205	5	form	form	NOUN
bptjm-29	205	6	of	of	ADP
bptjm-29	205	7	treatment	treatment	NOUN
bptjm-29	205	8	is	be	AUX
bptjm-29	205	9	that	that	SCONJ
bptjm-29	205	10	the	the	DET
bptjm-29	205	11	di	di	PROPN
bptjm-29	205	12	�	�	PROPN
bptjm-29	205	13	erent	erent	NOUN
bptjm-29	205	14	genes	gene	NOUN
bptjm-29	205	15	can	can	AUX
bptjm-29	205	16	be	be	AUX
bptjm-29	205	17	individually	individually	ADV
bptjm-29	205	18	suppressed	suppress	VERB
bptjm-29	205	19	by	by	ADP
bptjm-29	205	20	aso	aso	PROPN
bptjm-29	205	21	’s	’s	PART
bptjm-29	205	22	like	like	ADP
bptjm-29	205	23	tofersen	tofersen	NOUN
bptjm-29	205	24	to	to	PART
bptjm-29	205	25	reduce	reduce	VERB
bptjm-29	205	26	the	the	DET
bptjm-29	205	27	degree	degree	NOUN
bptjm-29	205	28	of	of	ADP
bptjm-29	205	29	toxic	toxic	ADJ
bptjm-29	205	30	variants	variant	NOUN
bptjm-29	205	31	.	.	PUNCT
bptjm-29	206	1	to	to	PART
bptjm-29	206	2	optimize	optimize	VERB
bptjm-29	206	3	gene	gene	NOUN
bptjm-29	206	4	therapy	therapy	NOUN
bptjm-29	206	5	for	for	ADP
bptjm-29	206	6	als	al	NOUN
bptjm-29	206	7	,	,	PUNCT
bptjm-29	206	8	the	the	DET
bptjm-29	206	9	pathological	pathological	ADJ
bptjm-29	206	10	mechanisms	mechanism	NOUN
bptjm-29	206	11	and	and	CCONJ
bptjm-29	206	12	roles	role	NOUN
bptjm-29	206	13	that	that	PRON
bptjm-29	206	14	the	the	DET
bptjm-29	206	15	genes	gene	NOUN
bptjm-29	206	16	play	play	VERB
bptjm-29	206	17	must	must	AUX
bptjm-29	206	18	be	be	AUX
bptjm-29	206	19	well	well	ADV
bptjm-29	206	20	understood	understand	VERB
bptjm-29	206	21	and	and	CCONJ
bptjm-29	206	22	develop	develop	VERB
bptjm-29	206	23	a	a	DET
bptjm-29	206	24	barrier	barrier	NOUN
bptjm-29	206	25	for	for	ADP
bptjm-29	206	26	further	further	ADJ
bptjm-29	206	27	propagation	propagation	NOUN
bptjm-29	206	28	of	of	ADP
bptjm-29	206	29	neurotoxic	neurotoxic	ADJ
bptjm-29	206	30	factors	factor	NOUN
bptjm-29	206	31	.	.	PUNCT
bptjm-29	207	1	the	the	DET
bptjm-29	207	2	limitations	limitation	NOUN
bptjm-29	207	3	and	and	CCONJ
bptjm-29	207	4	challenges	challenge	NOUN
bptjm-29	207	5	associated	associate	VERB
bptjm-29	207	6	with	with	ADP
bptjm-29	207	7	this	this	DET
bptjm-29	207	8	approach	approach	NOUN
bptjm-29	207	9	are	be	AUX
bptjm-29	207	10	that	that	SCONJ
bptjm-29	207	11	it	it	PRON
bptjm-29	207	12	is	be	AUX
bptjm-29	207	13	mostly	mostly	ADV
bptjm-29	207	14	used	use	VERB
bptjm-29	207	15	to	to	PART
bptjm-29	207	16	treat	treat	VERB
bptjm-29	207	17	fals	fal	NOUN
bptjm-29	207	18	cases	case	NOUN
bptjm-29	207	19	and	and	CCONJ
bptjm-29	207	20	very	very	ADV
bptjm-29	207	21	few	few	ADJ
bptjm-29	207	22	sals	sal	NOUN
bptjm-29	207	23	cases	case	NOUN
bptjm-29	207	24	.	.	PUNCT
bptjm-29	208	1	berkeley	berkeley	PROPN
bptjm-29	208	2	pharma	pharma	PROPN
bptjm-29	208	3	tech	tech	PROPN
bptjm-29	208	4	journal	journal	NOUN
bptjm-29	208	5	of	of	ADP
bptjm-29	208	6	medicine	medicine	NOUN
bptjm-29	208	7	|	|	ADV
bptjm-29	208	8	83	83	NUM
bptjm-29	208	9	https://www.zotero.org/google-docs/?jcbxsl	https://www.zotero.org/google-docs/?jcbxsl	PROPN
bptjm-29	208	10	https://www.zotero.org/google-docs/?i7urgl	https://www.zotero.org/google-docs/?i7urgl	PROPN
bptjm-29	208	11	https://www.zotero.org/google-docs/?xjpnwz	https://www.zotero.org/google-docs/?xjpnwz	PROPN
bptjm-29	208	12	figure	figure	NOUN
bptjm-29	208	13	2	2	NUM
bptjm-29	208	14	.	.	PUNCT
bptjm-29	209	1	pathways	pathway	NOUN
bptjm-29	209	2	linking	link	VERB
bptjm-29	209	3	sod1	sod1	ADJ
bptjm-29	209	4	mutations	mutation	NOUN
bptjm-29	209	5	to	to	PART
bptjm-29	209	6	als	als	VERB
bptjm-29	209	7	pathology	pathology	NOUN
bptjm-29	209	8	5	5	NUM
bptjm-29	209	9	.	.	PUNCT
bptjm-29	209	10	astrocyte	astrocyte	NOUN
bptjm-29	209	11	transplantation	transplantation	NOUN
bptjm-29	209	12	the	the	DET
bptjm-29	209	13	most	most	ADV
bptjm-29	209	14	abundant	abundant	ADJ
bptjm-29	209	15	glial	glial	ADJ
bptjm-29	209	16	cells	cell	NOUN
bptjm-29	209	17	within	within	ADP
bptjm-29	209	18	the	the	DET
bptjm-29	209	19	cns	cns	NOUN
bptjm-29	209	20	are	be	AUX
bptjm-29	209	21	astrocytes	astrocyte	NOUN
bptjm-29	209	22	,	,	PUNCT
bptjm-29	209	23	a	a	DET
bptjm-29	209	24	form	form	NOUN
bptjm-29	209	25	of	of	ADP
bptjm-29	209	26	brain	brain	NOUN
bptjm-29	209	27	cell	cell	NOUN
bptjm-29	209	28	that	that	PRON
bptjm-29	209	29	regulates	regulate	VERB
bptjm-29	209	30	neural	neural	ADJ
bptjm-29	209	31	functions	function	NOUN
bptjm-29	209	32	through	through	ADP
bptjm-29	209	33	signal	signal	PROPN
bptjm-29	209	34	di	di	PROPN
bptjm-29	209	35	�	�	PROPN
bptjm-29	209	36	usion	usion	NOUN
bptjm-29	209	37	.	.	PUNCT
bptjm-29	210	1	correspondingly	correspondingly	ADV
bptjm-29	210	2	,	,	PUNCT
bptjm-29	210	3	they	they	PRON
bptjm-29	210	4	are	be	AUX
bptjm-29	210	5	necessary	necessary	ADJ
bptjm-29	210	6	in	in	ADP
bptjm-29	210	7	the	the	DET
bptjm-29	210	8	cns	cns	NOUN
bptjm-29	210	9	for	for	ADP
bptjm-29	210	10	neuronal	neuronal	ADJ
bptjm-29	210	11	survival	survival	NOUN
bptjm-29	210	12	.	.	PUNCT
bptjm-29	211	1	any	any	DET
bptjm-29	211	2	changes	change	NOUN
bptjm-29	211	3	including	include	VERB
bptjm-29	211	4	stress	stress	NOUN
bptjm-29	211	5	or	or	CCONJ
bptjm-29	211	6	injury	injury	NOUN
bptjm-29	211	7	to	to	ADP
bptjm-29	211	8	the	the	DET
bptjm-29	211	9	cns	cns	NOUN
bptjm-29	211	10	cause	cause	VERB
bptjm-29	211	11	astrocytes	astrocyte	NOUN
bptjm-29	211	12	to	to	ADP
bptjm-29	211	13	transition	transition	NOUN
bptjm-29	211	14	from	from	ADP
bptjm-29	211	15	healthy	healthy	ADJ
bptjm-29	211	16	astrocytes	astrocyte	NOUN
bptjm-29	211	17	to	to	ADP
bptjm-29	211	18	a1	a1	NOUN
bptjm-29	211	19	-	-	PUNCT
bptjm-29	211	20	type	type	NOUN
bptjm-29	211	21	neurotoxic	neurotoxic	ADJ
bptjm-29	211	22	astrocytes	astrocyte	NOUN
bptjm-29	211	23	which	which	PRON
bptjm-29	211	24	promote	promote	VERB
bptjm-29	211	25	degeneration	degeneration	NOUN
bptjm-29	211	26	of	of	ADP
bptjm-29	211	27	motor	motor	NOUN
bptjm-29	211	28	neurons43	neurons43	NOUN
bptjm-29	211	29	.	.	PUNCT
bptjm-29	212	1	the	the	DET
bptjm-29	212	2	progression	progression	NOUN
bptjm-29	212	3	in	in	ADP
bptjm-29	212	4	toxicity	toxicity	NOUN
bptjm-29	212	5	of	of	ADP
bptjm-29	212	6	healthy	healthy	ADJ
bptjm-29	212	7	motor	motor	NOUN
bptjm-29	212	8	neurons	neuron	NOUN
bptjm-29	212	9	causes	cause	VERB
bptjm-29	212	10	a	a	DET
bptjm-29	212	11	loss	loss	NOUN
bptjm-29	212	12	in	in	ADP
bptjm-29	212	13	homeostatic	homeostatic	ADJ
bptjm-29	212	14	functions	function	NOUN
bptjm-29	212	15	or	or	CCONJ
bptjm-29	212	16	gain	gain	NOUN
bptjm-29	212	17	of	of	ADP
bptjm-29	212	18	toxic	toxic	ADJ
bptjm-29	212	19	functions	function	NOUN
bptjm-29	212	20	.	.	PUNCT
bptjm-29	213	1	astrocytes	astrocyte	NOUN
bptjm-29	213	2	of	of	ADP
bptjm-29	213	3	als	als	NOUN
bptjm-29	213	4	patients	patient	NOUN
bptjm-29	213	5	are	be	AUX
bptjm-29	213	6	characterized	characterize	VERB
bptjm-29	213	7	as	as	ADP
bptjm-29	213	8	a1	a1	NOUN
bptjm-29	213	9	-	-	PUNCT
bptjm-29	213	10	type	type	NOUN
bptjm-29	213	11	,	,	PUNCT
bptjm-29	213	12	and	and	CCONJ
bptjm-29	213	13	targeted	target	VERB
bptjm-29	213	14	therapies	therapy	NOUN
bptjm-29	213	15	to	to	PART
bptjm-29	213	16	control	control	VERB
bptjm-29	213	17	the	the	DET
bptjm-29	213	18	proliferation	proliferation	NOUN
bptjm-29	213	19	of	of	ADP
bptjm-29	213	20	neurotoxic	neurotoxic	ADJ
bptjm-29	213	21	astrocytes	astrocyte	NOUN
bptjm-29	213	22	are	be	AUX
bptjm-29	213	23	currently	currently	ADV
bptjm-29	213	24	being	be	AUX
bptjm-29	213	25	tested	test	VERB
bptjm-29	213	26	for	for	ADP
bptjm-29	213	27	als	al	NOUN
bptjm-29	213	28	.	.	PUNCT
bptjm-29	214	1	astrocyte	astrocyte	NOUN
bptjm-29	214	2	-	-	PUNCT
bptjm-29	214	3	targeted	target	VERB
bptjm-29	214	4	therapy	therapy	NOUN
bptjm-29	214	5	involves	involve	VERB
bptjm-29	214	6	restoring	restore	VERB
bptjm-29	214	7	the	the	DET
bptjm-29	214	8	function	function	NOUN
bptjm-29	214	9	of	of	ADP
bptjm-29	214	10	neurotoxic	neurotoxic	ADJ
bptjm-29	214	11	astrocytes	astrocyte	NOUN
bptjm-29	214	12	through	through	ADP
bptjm-29	214	13	the	the	DET
bptjm-29	214	14	transplantation	transplantation	NOUN
bptjm-29	214	15	of	of	ADP
bptjm-29	214	16	healthy	healthy	ADJ
bptjm-29	214	17	astrocytes43	astrocytes43	NOUN
bptjm-29	214	18	.	.	PUNCT
bptjm-29	215	1	while	while	SCONJ
bptjm-29	215	2	this	this	PRON
bptjm-29	215	3	decreases	decrease	VERB
bptjm-29	215	4	the	the	DET
bptjm-29	215	5	concentration	concentration	NOUN
bptjm-29	215	6	of	of	ADP
bptjm-29	215	7	misfolded	misfolde	VERB
bptjm-29	215	8	proteins	protein	NOUN
bptjm-29	215	9	and	and	CCONJ
bptjm-29	215	10	aids	aid	NOUN
bptjm-29	215	11	in	in	ADP
bptjm-29	215	12	neuroprotection	neuroprotection	NOUN
bptjm-29	215	13	,	,	PUNCT
bptjm-29	215	14	there	there	PRON
bptjm-29	215	15	is	be	VERB
bptjm-29	215	16	also	also	ADV
bptjm-29	215	17	the	the	DET
bptjm-29	215	18	risk	risk	NOUN
bptjm-29	215	19	that	that	SCONJ
bptjm-29	215	20	these	these	DET
bptjm-29	215	21	healthy	healthy	ADJ
bptjm-29	215	22	astrocytes	astrocyte	NOUN
bptjm-29	215	23	can	can	AUX
bptjm-29	215	24	undergo	undergo	VERB
bptjm-29	215	25	the	the	DET
bptjm-29	215	26	transition	transition	NOUN
bptjm-29	215	27	to	to	ADP
bptjm-29	215	28	a1	a1	NOUN
bptjm-29	215	29	-	-	PUNCT
bptjm-29	215	30	type	type	NOUN
bptjm-29	215	31	astrocytes	astrocyte	NOUN
bptjm-29	215	32	when	when	SCONJ
bptjm-29	215	33	they	they	PRON
bptjm-29	215	34	are	be	AUX
bptjm-29	215	35	introduced	introduce	VERB
bptjm-29	215	36	to	to	ADP
bptjm-29	215	37	the	the	DET
bptjm-29	215	38	cns	cns	PROPN
bptjm-29	215	39	of	of	ADP
bptjm-29	215	40	als	als	NOUN
bptjm-29	215	41	patients	patient	NOUN
bptjm-29	215	42	.	.	PUNCT
bptjm-29	216	1	this	this	DET
bptjm-29	216	2	new	new	ADJ
bptjm-29	216	3	environment	environment	NOUN
bptjm-29	216	4	can	can	AUX
bptjm-29	216	5	be	be	AUX
bptjm-29	216	6	toxic	toxic	ADJ
bptjm-29	216	7	to	to	ADP
bptjm-29	216	8	the	the	DET
bptjm-29	216	9	new	new	ADJ
bptjm-29	216	10	cells	cell	NOUN
bptjm-29	216	11	due	due	ADP
bptjm-29	216	12	to	to	ADP
bptjm-29	216	13	the	the	DET
bptjm-29	216	14	large	large	ADJ
bptjm-29	216	15	accumulation	accumulation	NOUN
bptjm-29	216	16	of	of	ADP
bptjm-29	216	17	misfolded	misfolde	VERB
bptjm-29	216	18	proteins	protein	NOUN
bptjm-29	216	19	.	.	PUNCT
bptjm-29	217	1	although	although	SCONJ
bptjm-29	217	2	it	it	PRON
bptjm-29	217	3	has	have	VERB
bptjm-29	217	4	berkeley	berkeley	PROPN
bptjm-29	217	5	pharma	pharma	PROPN
bptjm-29	217	6	tech	tech	NOUN
bptjm-29	217	7	journal	journal	NOUN
bptjm-29	217	8	of	of	ADP
bptjm-29	217	9	medicine	medicine	NOUN
bptjm-29	217	10	|	|	ADV
bptjm-29	217	11	84	84	NUM
bptjm-29	217	12	https://www.zotero.org/google-docs/?mkli6i	https://www.zotero.org/google-docs/?mkli6i	NOUN
bptjm-29	217	13	https://www.zotero.org/google-docs/?ibxc2b	https://www.zotero.org/google-docs/?ibxc2b	NOUN
bptjm-29	217	14	been	be	AUX
bptjm-29	217	15	deduced	deduce	VERB
bptjm-29	217	16	that	that	SCONJ
bptjm-29	217	17	astrocytes	astrocyte	NOUN
bptjm-29	217	18	secrete	secrete	VERB
bptjm-29	217	19	neuroprotective	neuroprotective	ADJ
bptjm-29	217	20	factors	factor	NOUN
bptjm-29	217	21	that	that	PRON
bptjm-29	217	22	di	di	NOUN
bptjm-29	217	23	�	�	PROPN
bptjm-29	217	24	use	use	NOUN
bptjm-29	217	25	to	to	ADP
bptjm-29	217	26	the	the	DET
bptjm-29	217	27	motor	motor	NOUN
bptjm-29	217	28	neurons	neuron	NOUN
bptjm-29	217	29	,	,	PUNCT
bptjm-29	217	30	later	later	ADJ
bptjm-29	217	31	mechanisms	mechanism	NOUN
bptjm-29	217	32	including	include	VERB
bptjm-29	217	33	their	their	PRON
bptjm-29	217	34	attachment	attachment	NOUN
bptjm-29	217	35	and	and	CCONJ
bptjm-29	217	36	long	long	ADJ
bptjm-29	217	37	-	-	PUNCT
bptjm-29	217	38	term	term	NOUN
bptjm-29	217	39	survival	survival	NOUN
bptjm-29	217	40	need	need	VERB
bptjm-29	217	41	to	to	PART
bptjm-29	217	42	be	be	AUX
bptjm-29	217	43	further	far	ADV
bptjm-29	217	44	explored	explore	VERB
bptjm-29	217	45	.	.	PUNCT
bptjm-29	218	1	in	in	ADP
bptjm-29	218	2	a	a	DET
bptjm-29	218	3	phase	phase	NOUN
bptjm-29	218	4	1/2a	1/2a	NUM
bptjm-29	218	5	trial	trial	NOUN
bptjm-29	218	6	,	,	PUNCT
bptjm-29	218	7	researchers	researcher	NOUN
bptjm-29	218	8	from	from	ADP
bptjm-29	218	9	cedars	cedar	NOUN
bptjm-29	218	10	-	-	PUNCT
bptjm-29	218	11	sinai	sinai	PROPN
bptjm-29	218	12	medical	medical	ADJ
bptjm-29	218	13	center	center	NOUN
bptjm-29	218	14	are	be	AUX
bptjm-29	218	15	hoping	hope	VERB
bptjm-29	218	16	to	to	PART
bptjm-29	218	17	�	�	VERB
bptjm-29	218	18	nd	nd	PRON
bptjm-29	218	19	a	a	DET
bptjm-29	218	20	long	long	ADV
bptjm-29	218	21	-	-	PUNCT
bptjm-29	218	22	lasting	last	VERB
bptjm-29	218	23	solution	solution	NOUN
bptjm-29	218	24	to	to	PART
bptjm-29	218	25	als	als	VERB
bptjm-29	218	26	by	by	ADP
bptjm-29	218	27	testing	test	VERB
bptjm-29	218	28	the	the	DET
bptjm-29	218	29	e	e	PROPN
bptjm-29	218	30	�	�	PROPN
bptjm-29	218	31	ectiveness	ectiveness	NOUN
bptjm-29	218	32	of	of	ADP
bptjm-29	218	33	their	their	PRON
bptjm-29	218	34	engineered	engineer	VERB
bptjm-29	218	35	neural	neural	ADJ
bptjm-29	218	36	progenitor	progenitor	NOUN
bptjm-29	218	37	cells	cell	NOUN
bptjm-29	218	38	which	which	PRON
bptjm-29	218	39	di	di	VERB
bptjm-29	218	40	�	�	PROPN
bptjm-29	218	41	erentiate	erentiate	NOUN
bptjm-29	218	42	into	into	ADP
bptjm-29	218	43	astrocytes	astrocyte	NOUN
bptjm-29	218	44	inside	inside	ADP
bptjm-29	218	45	the	the	DET
bptjm-29	218	46	body	body	NOUN
bptjm-29	218	47	to	to	PART
bptjm-29	218	48	secrete	secrete	VERB
bptjm-29	218	49	the	the	DET
bptjm-29	218	50	gdnf	gdnf	ADJ
bptjm-29	218	51	protein	protein	NOUN
bptjm-29	218	52	,	,	PUNCT
bptjm-29	218	53	promoting	promote	VERB
bptjm-29	218	54	astrocyte	astrocyte	NOUN
bptjm-29	218	55	survival44	survival44	ADJ
bptjm-29	218	56	.	.	PUNCT
bptjm-29	219	1	cns10	cns10	ADJ
bptjm-29	219	2	-	-	PUNCT
bptjm-29	219	3	npc	npc	NOUN
bptjm-29	219	4	-	-	ADJ
bptjm-29	219	5	gdnf	gdnf	NOUN
bptjm-29	219	6	are	be	AUX
bptjm-29	219	7	progenitor	progenitor	NOUN
bptjm-29	219	8	cells	cell	NOUN
bptjm-29	219	9	which	which	PRON
bptjm-29	219	10	will	will	AUX
bptjm-29	219	11	release	release	VERB
bptjm-29	219	12	paracrine	paracrine	NOUN
bptjm-29	219	13	factors	factor	NOUN
bptjm-29	219	14	inside	inside	ADP
bptjm-29	219	15	the	the	DET
bptjm-29	219	16	body	body	NOUN
bptjm-29	219	17	.	.	PUNCT
bptjm-29	220	1	as	as	SCONJ
bptjm-29	220	2	they	they	PRON
bptjm-29	220	3	release	release	VERB
bptjm-29	220	4	gdnf	gdnf	NOUN
bptjm-29	220	5	,	,	PUNCT
bptjm-29	220	6	this	this	DET
bptjm-29	220	7	neuroprotective	neuroprotective	ADJ
bptjm-29	220	8	factor	factor	NOUN
bptjm-29	220	9	is	be	AUX
bptjm-29	220	10	also	also	ADV
bptjm-29	220	11	transferred	transfer	VERB
bptjm-29	220	12	to	to	ADP
bptjm-29	220	13	dying	die	VERB
bptjm-29	220	14	motor	motor	NOUN
bptjm-29	220	15	neurons	neuron	NOUN
bptjm-29	220	16	in	in	ADP
bptjm-29	220	17	the	the	DET
bptjm-29	220	18	motor	motor	NOUN
bptjm-29	220	19	cortex	cortex	NOUN
bptjm-29	220	20	.	.	PUNCT
bptjm-29	221	1	two	two	NUM
bptjm-29	221	2	doses	dose	NOUN
bptjm-29	221	3	of	of	ADP
bptjm-29	221	4	adult	adult	NOUN
bptjm-29	221	5	stem	stem	NOUN
bptjm-29	221	6	cells	cell	NOUN
bptjm-29	221	7	will	will	AUX
bptjm-29	221	8	be	be	AUX
bptjm-29	221	9	delivered	deliver	VERB
bptjm-29	221	10	to	to	ADP
bptjm-29	221	11	the	the	DET
bptjm-29	221	12	cortical	cortical	ADJ
bptjm-29	221	13	area	area	NOUN
bptjm-29	221	14	of	of	ADP
bptjm-29	221	15	the	the	DET
bptjm-29	221	16	human	human	ADJ
bptjm-29	221	17	primary	primary	ADJ
bptjm-29	221	18	motor	motor	NOUN
bptjm-29	221	19	cortex	cortex	NOUN
bptjm-29	221	20	(	(	PUNCT
bptjm-29	221	21	m1	m1	NOUN
bptjm-29	221	22	)	)	PUNCT
bptjm-29	221	23	as	as	SCONJ
bptjm-29	221	24	researchers	researcher	NOUN
bptjm-29	221	25	observe	observe	VERB
bptjm-29	221	26	for	for	ADP
bptjm-29	221	27	signs	sign	NOUN
bptjm-29	221	28	of	of	ADP
bptjm-29	221	29	repaired	repair	VERB
bptjm-29	221	30	upper	upper	ADJ
bptjm-29	221	31	motor	motor	NOUN
bptjm-29	221	32	neurons	neuron	NOUN
bptjm-29	221	33	and	and	CCONJ
bptjm-29	221	34	improvement	improvement	NOUN
bptjm-29	221	35	in	in	ADP
bptjm-29	221	36	hand	hand	NOUN
bptjm-29	221	37	function	function	NOUN
bptjm-29	221	38	.	.	PUNCT
bptjm-29	222	1	signs	sign	NOUN
bptjm-29	222	2	of	of	ADP
bptjm-29	222	3	potential	potential	ADJ
bptjm-29	222	4	e	e	NOUN
bptjm-29	222	5	�	�	NOUN
bptjm-29	222	6	cacy	cacy	NOUN
bptjm-29	222	7	will	will	AUX
bptjm-29	222	8	be	be	AUX
bptjm-29	222	9	determined	determine	VERB
bptjm-29	222	10	by	by	ADP
bptjm-29	222	11	comparing	compare	VERB
bptjm-29	222	12	the	the	DET
bptjm-29	222	13	di	di	PROPN
bptjm-29	222	14	�	�	PROPN
bptjm-29	222	15	erence	erence	NOUN
bptjm-29	222	16	in	in	ADP
bptjm-29	222	17	rate	rate	NOUN
bptjm-29	222	18	of	of	ADP
bptjm-29	222	19	loss	loss	NOUN
bptjm-29	222	20	of	of	ADP
bptjm-29	222	21	hand	hand	NOUN
bptjm-29	222	22	strength	strength	NOUN
bptjm-29	222	23	between	between	ADP
bptjm-29	222	24	the	the	DET
bptjm-29	222	25	two	two	NUM
bptjm-29	222	26	sides	side	NOUN
bptjm-29	222	27	.	.	PUNCT
bptjm-29	223	1	studies	study	NOUN
bptjm-29	223	2	relating	relate	VERB
bptjm-29	223	3	als	al	NOUN
bptjm-29	223	4	-	-	PUNCT
bptjm-29	223	5	genes	gene	NOUN
bptjm-29	223	6	to	to	PART
bptjm-29	223	7	astrocyte	astrocyte	NOUN
bptjm-29	223	8	therapies	therapy	NOUN
bptjm-29	223	9	noted	note	VERB
bptjm-29	223	10	that	that	SCONJ
bptjm-29	223	11	msod1	msod1	NOUN
bptjm-29	223	12	-	-	PUNCT
bptjm-29	223	13	expressing	express	VERB
bptjm-29	223	14	astrocytes	astrocyte	NOUN
bptjm-29	223	15	induced	induce	VERB
bptjm-29	223	16	selective	selective	ADJ
bptjm-29	223	17	death	death	NOUN
bptjm-29	223	18	of	of	ADP
bptjm-29	223	19	spinal	spinal	ADJ
bptjm-29	223	20	motor	motor	NOUN
bptjm-29	223	21	neurons	neuron	NOUN
bptjm-29	223	22	,	,	PUNCT
bptjm-29	223	23	so	so	SCONJ
bptjm-29	223	24	a	a	DET
bptjm-29	223	25	potential	potential	ADJ
bptjm-29	223	26	solution	solution	NOUN
bptjm-29	223	27	could	could	AUX
bptjm-29	223	28	be	be	AUX
bptjm-29	223	29	the	the	DET
bptjm-29	223	30	transplantation	transplantation	NOUN
bptjm-29	223	31	of	of	ADP
bptjm-29	223	32	healthy	healthy	ADJ
bptjm-29	223	33	astrocytes	astrocyte	NOUN
bptjm-29	223	34	or	or	CCONJ
bptjm-29	223	35	selective	selective	ADJ
bptjm-29	223	36	silencing	silencing	NOUN
bptjm-29	223	37	of	of	ADP
bptjm-29	223	38	the	the	DET
bptjm-29	223	39	msod1	msod1	NOUN
bptjm-29	223	40	gene	gene	NOUN
bptjm-29	223	41	in	in	ADP
bptjm-29	223	42	astrocytes	astrocyte	NOUN
bptjm-29	223	43	.	.	PUNCT
bptjm-29	224	1	while	while	SCONJ
bptjm-29	224	2	many	many	ADJ
bptjm-29	224	3	hypotheses	hypothesis	NOUN
bptjm-29	224	4	are	be	AUX
bptjm-29	224	5	developed	develop	VERB
bptjm-29	224	6	,	,	PUNCT
bptjm-29	224	7	it	it	PRON
bptjm-29	224	8	is	be	AUX
bptjm-29	224	9	believed	believe	VERB
bptjm-29	224	10	that	that	SCONJ
bptjm-29	224	11	transplanting	transplant	VERB
bptjm-29	224	12	healthy	healthy	ADJ
bptjm-29	224	13	astrocytes	astrocyte	NOUN
bptjm-29	224	14	will	will	AUX
bptjm-29	224	15	generate	generate	VERB
bptjm-29	224	16	a	a	DET
bptjm-29	224	17	better	well	ADJ
bptjm-29	224	18	environment	environment	NOUN
bptjm-29	224	19	for	for	ADP
bptjm-29	224	20	the	the	DET
bptjm-29	224	21	motor	motor	NOUN
bptjm-29	224	22	neurons	neuron	NOUN
bptjm-29	224	23	.	.	PUNCT
bptjm-29	225	1	therefore	therefore	ADV
bptjm-29	225	2	,	,	PUNCT
bptjm-29	225	3	the	the	DET
bptjm-29	225	4	molecular	molecular	ADJ
bptjm-29	225	5	pathology	pathology	NOUN
bptjm-29	225	6	of	of	ADP
bptjm-29	225	7	astrocytes	astrocyte	NOUN
bptjm-29	225	8	in	in	ADP
bptjm-29	225	9	als	als	NOUN
bptjm-29	225	10	patients	patient	NOUN
bptjm-29	225	11	needs	need	VERB
bptjm-29	225	12	to	to	PART
bptjm-29	225	13	be	be	AUX
bptjm-29	225	14	further	far	ADV
bptjm-29	225	15	studied	study	VERB
bptjm-29	225	16	.	.	PUNCT
bptjm-29	226	1	once	once	ADV
bptjm-29	226	2	the	the	DET
bptjm-29	226	3	healthy	healthy	ADJ
bptjm-29	226	4	cells	cell	NOUN
bptjm-29	226	5	are	be	AUX
bptjm-29	226	6	delivered	deliver	VERB
bptjm-29	226	7	,	,	PUNCT
bptjm-29	226	8	the	the	DET
bptjm-29	226	9	pathway	pathway	NOUN
bptjm-29	226	10	it	it	PRON
bptjm-29	226	11	takes	take	VERB
bptjm-29	226	12	for	for	ADP
bptjm-29	226	13	di	di	NOUN
bptjm-29	226	14	�	�	PROPN
bptjm-29	226	15	usion	usion	NOUN
bptjm-29	226	16	and	and	CCONJ
bptjm-29	226	17	speci	speci	PROPN
bptjm-29	226	18	�	�	PROPN
bptjm-29	226	19	c	c	PROPN
bptjm-29	226	20	function	function	NOUN
bptjm-29	226	21	remains	remain	VERB
bptjm-29	226	22	unknown45	unknown45	ADJ
bptjm-29	226	23	.	.	PUNCT
bptjm-29	227	1	while	while	SCONJ
bptjm-29	227	2	this	this	DET
bptjm-29	227	3	treatment	treatment	NOUN
bptjm-29	227	4	is	be	AUX
bptjm-29	227	5	appealing	appeal	VERB
bptjm-29	227	6	because	because	SCONJ
bptjm-29	227	7	it	it	PRON
bptjm-29	227	8	has	have	VERB
bptjm-29	227	9	the	the	DET
bptjm-29	227	10	potential	potential	NOUN
bptjm-29	227	11	of	of	ADP
bptjm-29	227	12	restricting	restrict	VERB
bptjm-29	227	13	the	the	DET
bptjm-29	227	14	propagation	propagation	NOUN
bptjm-29	227	15	of	of	ADP
bptjm-29	227	16	toxic	toxic	ADJ
bptjm-29	227	17	cells	cell	NOUN
bptjm-29	227	18	and	and	CCONJ
bptjm-29	227	19	slowing	slow	VERB
bptjm-29	227	20	degeneration	degeneration	NOUN
bptjm-29	227	21	,	,	PUNCT
bptjm-29	227	22	transplanted	transplant	VERB
bptjm-29	227	23	cells	cell	NOUN
bptjm-29	227	24	can	can	AUX
bptjm-29	227	25	still	still	ADV
bptjm-29	227	26	transform	transform	VERB
bptjm-29	227	27	into	into	ADP
bptjm-29	227	28	a1	a1	NOUN
bptjm-29	227	29	reactive	reactive	ADJ
bptjm-29	227	30	astrocytes	astrocyte	NOUN
bptjm-29	227	31	once	once	SCONJ
bptjm-29	227	32	they	they	PRON
bptjm-29	227	33	are	be	AUX
bptjm-29	227	34	introduced	introduce	VERB
bptjm-29	227	35	to	to	ADP
bptjm-29	227	36	a	a	DET
bptjm-29	227	37	more	more	ADV
bptjm-29	227	38	neurotoxic	neurotoxic	ADJ
bptjm-29	227	39	environment	environment	NOUN
bptjm-29	227	40	.	.	PUNCT
bptjm-29	228	1	under	under	ADP
bptjm-29	228	2	excitotoxic	excitotoxic	ADJ
bptjm-29	228	3	conditions	condition	NOUN
bptjm-29	228	4	,	,	PUNCT
bptjm-29	228	5	als	als	VERB
bptjm-29	228	6	neurons	neuron	NOUN
bptjm-29	228	7	and	and	CCONJ
bptjm-29	228	8	astrocytes	astrocyte	NOUN
bptjm-29	228	9	can	can	AUX
bptjm-29	228	10	be	be	AUX
bptjm-29	228	11	more	more	ADV
bptjm-29	228	12	sensitive	sensitive	ADJ
bptjm-29	228	13	to	to	ADP
bptjm-29	228	14	neuromodulation	neuromodulation	NOUN
bptjm-29	228	15	,	,	PUNCT
bptjm-29	228	16	so	so	CCONJ
bptjm-29	228	17	it	it	PRON
bptjm-29	228	18	is	be	AUX
bptjm-29	228	19	pivotal	pivotal	ADJ
bptjm-29	228	20	to	to	ADP
bptjm-29	228	21	developing	develop	VERB
bptjm-29	228	22	novel	novel	ADJ
bptjm-29	228	23	cell	cell	NOUN
bptjm-29	228	24	therapies	therapy	NOUN
bptjm-29	228	25	for	for	ADP
bptjm-29	228	26	als	al	NOUN
bptjm-29	228	27	.	.	PUNCT
bptjm-29	229	1	6	6	X
bptjm-29	229	2	.	.	PUNCT
bptjm-29	229	3	stem	stem	NOUN
bptjm-29	229	4	cells	cell	NOUN
bptjm-29	229	5	because	because	SCONJ
bptjm-29	229	6	the	the	DET
bptjm-29	229	7	focus	focus	NOUN
bptjm-29	229	8	of	of	ADP
bptjm-29	229	9	this	this	DET
bptjm-29	229	10	paper	paper	NOUN
bptjm-29	229	11	is	be	AUX
bptjm-29	229	12	the	the	DET
bptjm-29	229	13	application	application	NOUN
bptjm-29	229	14	of	of	ADP
bptjm-29	229	15	mesenchymal	mesenchymal	ADJ
bptjm-29	229	16	stem	stem	NOUN
bptjm-29	229	17	cells	cell	NOUN
bptjm-29	229	18	(	(	PUNCT
bptjm-29	229	19	msc	msc	PROPN
bptjm-29	229	20	)	)	PUNCT
bptjm-29	229	21	as	as	ADP
bptjm-29	229	22	a	a	DET
bptjm-29	229	23	therapeutic	therapeutic	NOUN
bptjm-29	229	24	for	for	ADP
bptjm-29	229	25	als	al	NOUN
bptjm-29	229	26	,	,	PUNCT
bptjm-29	229	27	it	it	PRON
bptjm-29	229	28	is	be	AUX
bptjm-29	229	29	imperative	imperative	ADJ
bptjm-29	229	30	to	to	PART
bptjm-29	229	31	broadly	broadly	ADV
bptjm-29	229	32	consider	consider	VERB
bptjm-29	229	33	stem	stem	NOUN
bptjm-29	229	34	berkeley	berkeley	PROPN
bptjm-29	229	35	pharma	pharma	PROPN
bptjm-29	229	36	tech	tech	NOUN
bptjm-29	229	37	journal	journal	NOUN
bptjm-29	229	38	of	of	ADP
bptjm-29	229	39	medicine	medicine	NOUN
bptjm-29	229	40	|	|	ADV
bptjm-29	229	41	85	85	NUM
bptjm-29	229	42	https://www.zotero.org/google-docs/?6icqrh	https://www.zotero.org/google-docs/?6icqrh	NOUN
bptjm-29	229	43	https://www.zotero.org/google-docs/?4zrbtd	https://www.zotero.org/google-docs/?4zrbtd	PROPN
bptjm-29	229	44	cells	cell	NOUN
bptjm-29	229	45	,	,	PUNCT
bptjm-29	229	46	their	their	PRON
bptjm-29	229	47	capabilities	capability	NOUN
bptjm-29	229	48	,	,	PUNCT
bptjm-29	229	49	and	and	CCONJ
bptjm-29	229	50	their	their	PRON
bptjm-29	229	51	advances	advance	NOUN
bptjm-29	229	52	in	in	ADP
bptjm-29	229	53	pertinence	pertinence	NOUN
bptjm-29	229	54	to	to	ADP
bptjm-29	229	55	regenerative	regenerative	ADJ
bptjm-29	229	56	medicine	medicine	NOUN
bptjm-29	229	57	(	(	PUNCT
bptjm-29	229	58	a	a	DET
bptjm-29	229	59	process	process	NOUN
bptjm-29	229	60	by	by	ADP
bptjm-29	229	61	which	which	PRON
bptjm-29	229	62	healthy	healthy	ADJ
bptjm-29	229	63	cells	cell	NOUN
bptjm-29	229	64	are	be	AUX
bptjm-29	229	65	introduced	introduce	VERB
bptjm-29	229	66	in	in	ADP
bptjm-29	229	67	order	order	NOUN
bptjm-29	229	68	to	to	PART
bptjm-29	229	69	replace	replace	VERB
bptjm-29	229	70	cells	cell	NOUN
bptjm-29	229	71	that	that	PRON
bptjm-29	229	72	have	have	AUX
bptjm-29	229	73	been	be	AUX
bptjm-29	229	74	adversely	adversely	ADV
bptjm-29	229	75	impacted	impact	VERB
bptjm-29	229	76	by	by	ADP
bptjm-29	229	77	disease	disease	NOUN
bptjm-29	229	78	)	)	PUNCT
bptjm-29	229	79	and	and	CCONJ
bptjm-29	229	80	disease	disease	NOUN
bptjm-29	229	81	therapeutics46	therapeutics46	PROPN
bptjm-29	229	82	.	.	PUNCT
bptjm-29	230	1	stem	stem	NOUN
bptjm-29	230	2	cells	cell	NOUN
bptjm-29	230	3	are	be	AUX
bptjm-29	230	4	cells	cell	NOUN
bptjm-29	230	5	from	from	ADP
bptjm-29	230	6	which	which	PRON
bptjm-29	230	7	di	di	NOUN
bptjm-29	230	8	�	�	PROPN
bptjm-29	230	9	erentiated	erentiate	VERB
bptjm-29	230	10	daughter	daughter	NOUN
bptjm-29	230	11	cells	cell	NOUN
bptjm-29	230	12	,	,	PUNCT
bptjm-29	230	13	or	or	CCONJ
bptjm-29	230	14	cells	cell	NOUN
bptjm-29	230	15	with	with	ADP
bptjm-29	230	16	a	a	DET
bptjm-29	230	17	specialized	specialized	ADJ
bptjm-29	230	18	function	function	NOUN
bptjm-29	230	19	,	,	PUNCT
bptjm-29	230	20	can	can	AUX
bptjm-29	230	21	be	be	AUX
bptjm-29	230	22	engendered	engender	VERB
bptjm-29	230	23	within	within	ADP
bptjm-29	230	24	the	the	DET
bptjm-29	230	25	human	human	ADJ
bptjm-29	230	26	body	body	NOUN
bptjm-29	230	27	.	.	PUNCT
bptjm-29	231	1	daughter	daughter	NOUN
bptjm-29	231	2	cells	cell	NOUN
bptjm-29	231	3	are	be	AUX
bptjm-29	231	4	cells	cell	NOUN
bptjm-29	231	5	that	that	PRON
bptjm-29	231	6	result	result	VERB
bptjm-29	231	7	from	from	ADP
bptjm-29	231	8	the	the	DET
bptjm-29	231	9	mitotic	mitotic	ADJ
bptjm-29	231	10	or	or	CCONJ
bptjm-29	231	11	meiotic	meiotic	ADJ
bptjm-29	231	12	reproductive	reproductive	ADJ
bptjm-29	231	13	division	division	NOUN
bptjm-29	231	14	of	of	ADP
bptjm-29	231	15	a	a	DET
bptjm-29	231	16	singular	singular	ADJ
bptjm-29	231	17	cell	cell	NOUN
bptjm-29	231	18	,	,	PUNCT
bptjm-29	231	19	and	and	CCONJ
bptjm-29	231	20	possess	possess	VERB
bptjm-29	231	21	a	a	DET
bptjm-29	231	22	speci	speci	ADJ
bptjm-29	231	23	�	�	PROPN
bptjm-29	231	24	c	c	NOUN
bptjm-29	231	25	function	function	NOUN
bptjm-29	231	26	;	;	PUNCT
bptjm-29	231	27	examples	example	NOUN
bptjm-29	231	28	include	include	VERB
bptjm-29	231	29	epithelial	epithelial	ADJ
bptjm-29	231	30	cells	cell	NOUN
bptjm-29	231	31	,	,	PUNCT
bptjm-29	231	32	adipose	adipose	ADP
bptjm-29	231	33	stromal	stromal	ADJ
bptjm-29	231	34	cells	cell	NOUN
bptjm-29	231	35	,	,	PUNCT
bptjm-29	231	36	and	and	CCONJ
bptjm-29	231	37	smooth	smooth	ADJ
bptjm-29	231	38	muscle	muscle	NOUN
bptjm-29	231	39	cells	cell	NOUN
bptjm-29	231	40	.	.	PUNCT
bptjm-29	232	1	furthermore	furthermore	ADV
bptjm-29	232	2	,	,	PUNCT
bptjm-29	232	3	these	these	DET
bptjm-29	232	4	cells	cell	NOUN
bptjm-29	232	5	are	be	AUX
bptjm-29	232	6	undi	undi	ADJ
bptjm-29	232	7	�	�	NOUN
bptjm-29	232	8	erentiated	erentiate	VERB
bptjm-29	232	9	and	and	CCONJ
bptjm-29	232	10	are	be	AUX
bptjm-29	232	11	typically	typically	ADV
bptjm-29	232	12	sourced	source	VERB
bptjm-29	232	13	from	from	ADP
bptjm-29	232	14	adult	adult	NOUN
bptjm-29	232	15	,	,	PUNCT
bptjm-29	232	16	fetal	fetal	ADJ
bptjm-29	232	17	,	,	PUNCT
bptjm-29	232	18	and	and	CCONJ
bptjm-29	232	19	embryonic	embryonic	ADJ
bptjm-29	232	20	tissue	tissue	NOUN
bptjm-29	232	21	,	,	PUNCT
bptjm-29	232	22	in	in	ADP
bptjm-29	232	23	addition	addition	NOUN
bptjm-29	232	24	to	to	ADP
bptjm-29	232	25	di	di	NOUN
bptjm-29	232	26	�	�	PROPN
bptjm-29	232	27	erentiated	erentiate	VERB
bptjm-29	232	28	somatic	somatic	ADJ
bptjm-29	232	29	cells47	cells47	NOUN
bptjm-29	232	30	.	.	PUNCT
bptjm-29	233	1	there	there	PRON
bptjm-29	233	2	are	be	VERB
bptjm-29	233	3	four	four	NUM
bptjm-29	233	4	main	main	ADJ
bptjm-29	233	5	forms	form	NOUN
bptjm-29	233	6	of	of	ADP
bptjm-29	233	7	stem	stem	NOUN
bptjm-29	233	8	cells	cell	NOUN
bptjm-29	233	9	:	:	PUNCT
bptjm-29	233	10	adult	adult	NOUN
bptjm-29	233	11	,	,	PUNCT
bptjm-29	233	12	embryonic	embryonic	ADJ
bptjm-29	233	13	,	,	PUNCT
bptjm-29	233	14	induced	induced	ADJ
bptjm-29	233	15	pluripotent	pluripotent	NOUN
bptjm-29	233	16	,	,	PUNCT
bptjm-29	233	17	and	and	CCONJ
bptjm-29	233	18	mesenchymal48	mesenchymal48	NOUN
bptjm-29	233	19	.	.	PUNCT
bptjm-29	234	1	6.1	6.1	NUM
bptjm-29	234	2	.	.	PUNCT
bptjm-29	234	3	adult	adult	NOUN
bptjm-29	234	4	stem	stem	NOUN
bptjm-29	234	5	cells	cell	NOUN
bptjm-29	234	6	adult	adult	NOUN
bptjm-29	234	7	stem	stem	NOUN
bptjm-29	234	8	cells	cell	NOUN
bptjm-29	234	9	are	be	AUX
bptjm-29	234	10	commonly	commonly	ADV
bptjm-29	234	11	regarded	regard	VERB
bptjm-29	234	12	as	as	ADP
bptjm-29	234	13	tissue	tissue	NOUN
bptjm-29	234	14	-	-	PUNCT
bptjm-29	234	15	speci	speci	NOUN
bptjm-29	234	16	�	�	PROPN
bptjm-29	234	17	c	c	NOUN
bptjm-29	234	18	or	or	CCONJ
bptjm-29	234	19	somatic	somatic	ADJ
bptjm-29	234	20	stem	stem	NOUN
bptjm-29	234	21	cells	cell	NOUN
bptjm-29	234	22	,	,	PUNCT
bptjm-29	234	23	and	and	CCONJ
bptjm-29	234	24	are	be	AUX
bptjm-29	234	25	found	find	VERB
bptjm-29	234	26	in	in	ADP
bptjm-29	234	27	a	a	DET
bptjm-29	234	28	wide	wide	ADJ
bptjm-29	234	29	range	range	NOUN
bptjm-29	234	30	of	of	ADP
bptjm-29	234	31	tissues	tissue	NOUN
bptjm-29	234	32	,	,	PUNCT
bptjm-29	234	33	including	include	VERB
bptjm-29	234	34	the	the	DET
bptjm-29	234	35	brain	brain	NOUN
bptjm-29	234	36	,	,	PUNCT
bptjm-29	234	37	heart	heart	NOUN
bptjm-29	234	38	,	,	PUNCT
bptjm-29	234	39	liver	liver	NOUN
bptjm-29	234	40	,	,	PUNCT
bptjm-29	234	41	and	and	CCONJ
bptjm-29	234	42	bone	bone	NOUN
bptjm-29	234	43	marrow	marrow	NOUN
bptjm-29	234	44	.	.	PUNCT
bptjm-29	235	1	they	they	PRON
bptjm-29	235	2	can	can	AUX
bptjm-29	235	3	facilitate	facilitate	VERB
bptjm-29	235	4	the	the	DET
bptjm-29	235	5	creation	creation	NOUN
bptjm-29	235	6	of	of	ADP
bptjm-29	235	7	various	various	ADJ
bptjm-29	235	8	cell	cell	NOUN
bptjm-29	235	9	types	type	NOUN
bptjm-29	235	10	upon	upon	SCONJ
bptjm-29	235	11	injury	injury	NOUN
bptjm-29	235	12	,	,	PUNCT
bptjm-29	235	13	but	but	CCONJ
bptjm-29	235	14	the	the	DET
bptjm-29	235	15	degree	degree	NOUN
bptjm-29	235	16	to	to	PART
bptjm-29	235	17	which	which	PRON
bptjm-29	235	18	this	this	DET
bptjm-29	235	19	di	di	NOUN
bptjm-29	235	20	�	�	PROPN
bptjm-29	235	21	erentiation	erentiation	NOUN
bptjm-29	235	22	can	can	AUX
bptjm-29	235	23	occur	occur	VERB
bptjm-29	235	24	is	be	AUX
bptjm-29	235	25	limited	limit	VERB
bptjm-29	235	26	in	in	ADP
bptjm-29	235	27	comparison	comparison	NOUN
bptjm-29	235	28	to	to	PART
bptjm-29	235	29	embryonic	embryonic	VERB
bptjm-29	235	30	stem	stem	NOUN
bptjm-29	235	31	cells	cell	NOUN
bptjm-29	235	32	.	.	PUNCT
bptjm-29	236	1	adult	adult	NOUN
bptjm-29	236	2	stem	stem	NOUN
bptjm-29	236	3	cells	cell	NOUN
bptjm-29	236	4	are	be	AUX
bptjm-29	236	5	multipotent	multipotent	NOUN
bptjm-29	236	6	,	,	PUNCT
bptjm-29	236	7	or	or	CCONJ
bptjm-29	236	8	limited	limit	VERB
bptjm-29	236	9	to	to	ADP
bptjm-29	236	10	di	di	NOUN
bptjm-29	236	11	�	�	PROPN
bptjm-29	236	12	erentiating	erentiate	VERB
bptjm-29	236	13	into	into	ADP
bptjm-29	236	14	the	the	DET
bptjm-29	236	15	specialized	specialized	ADJ
bptjm-29	236	16	cell	cell	NOUN
bptjm-29	236	17	type	type	NOUN
bptjm-29	236	18	in	in	ADP
bptjm-29	236	19	the	the	DET
bptjm-29	236	20	tissue	tissue	NOUN
bptjm-29	236	21	or	or	CCONJ
bptjm-29	236	22	organ	organ	NOUN
bptjm-29	236	23	of	of	ADP
bptjm-29	236	24	residence	residence	NOUN
bptjm-29	236	25	.	.	PUNCT
bptjm-29	237	1	they	they	PRON
bptjm-29	237	2	can	can	AUX
bptjm-29	237	3	also	also	ADV
bptjm-29	237	4	be	be	AUX
bptjm-29	237	5	utilized	utilize	VERB
bptjm-29	237	6	for	for	ADP
bptjm-29	237	7	general	general	ADJ
bptjm-29	237	8	maintenance	maintenance	NOUN
bptjm-29	237	9	of	of	ADP
bptjm-29	237	10	tissue	tissue	NOUN
bptjm-29	237	11	and	and	CCONJ
bptjm-29	237	12	organs	organ	NOUN
bptjm-29	237	13	and	and	CCONJ
bptjm-29	237	14	have	have	VERB
bptjm-29	237	15	the	the	DET
bptjm-29	237	16	capacity	capacity	NOUN
bptjm-29	237	17	to	to	PART
bptjm-29	237	18	maintain	maintain	VERB
bptjm-29	237	19	and	and	CCONJ
bptjm-29	237	20	repair	repair	VERB
bptjm-29	237	21	organs	organ	NOUN
bptjm-29	237	22	and	and	CCONJ
bptjm-29	237	23	bodily	bodily	ADJ
bptjm-29	237	24	tissue	tissue	NOUN
bptjm-29	237	25	,	,	PUNCT
bptjm-29	237	26	which	which	PRON
bptjm-29	237	27	can	can	AUX
bptjm-29	237	28	give	give	VERB
bptjm-29	237	29	rise	rise	NOUN
bptjm-29	237	30	to	to	ADP
bptjm-29	237	31	cell	cell	NOUN
bptjm-29	237	32	regeneration	regeneration	NOUN
bptjm-29	237	33	,	,	PUNCT
bptjm-29	237	34	thus	thus	ADV
bptjm-29	237	35	indicative	indicative	ADJ
bptjm-29	237	36	of	of	ADP
bptjm-29	237	37	the	the	DET
bptjm-29	237	38	role	role	NOUN
bptjm-29	237	39	stem	stem	NOUN
bptjm-29	237	40	cells	cell	NOUN
bptjm-29	237	41	can	can	AUX
bptjm-29	237	42	play	play	VERB
bptjm-29	237	43	within	within	ADP
bptjm-29	237	44	regenerative	regenerative	ADJ
bptjm-29	237	45	medicine49	medicine49	NOUN
bptjm-29	237	46	,	,	PUNCT
bptjm-29	237	47	50	50	NUM
bptjm-29	237	48	.	.	NOUN
bptjm-29	237	49	6.2	6.2	NUM
bptjm-29	237	50	.	.	PUNCT
bptjm-29	238	1	embryonic	embryonic	ADJ
bptjm-29	238	2	stem	stem	NOUN
bptjm-29	238	3	cells	cell	NOUN
bptjm-29	238	4	embryonic	embryonic	ADJ
bptjm-29	238	5	stem	stem	NOUN
bptjm-29	238	6	cells	cell	NOUN
bptjm-29	238	7	(	(	PUNCT
bptjm-29	238	8	escs	esc	NOUN
bptjm-29	238	9	)	)	PUNCT
bptjm-29	238	10	are	be	AUX
bptjm-29	238	11	conventionally	conventionally	ADV
bptjm-29	238	12	sourced	source	VERB
bptjm-29	238	13	from	from	ADP
bptjm-29	238	14	embryos	embryo	NOUN
bptjm-29	238	15	three	three	NUM
bptjm-29	238	16	to	to	ADP
bptjm-29	238	17	�	�	PROPN
bptjm-29	238	18	ve	ve	NOUN
bptjm-29	238	19	years	year	NOUN
bptjm-29	238	20	of	of	ADP
bptjm-29	238	21	age	age	NOUN
bptjm-29	238	22	and	and	CCONJ
bptjm-29	238	23	are	be	AUX
bptjm-29	238	24	more	more	ADV
bptjm-29	238	25	versatile	versatile	ADJ
bptjm-29	238	26	in	in	ADP
bptjm-29	238	27	comparison	comparison	NOUN
bptjm-29	238	28	to	to	ADP
bptjm-29	238	29	adult	adult	NOUN
bptjm-29	238	30	stem	stem	NOUN
bptjm-29	238	31	cells	cell	NOUN
bptjm-29	238	32	because	because	SCONJ
bptjm-29	238	33	they	they	PRON
bptjm-29	238	34	are	be	AUX
bptjm-29	238	35	pluripotent	pluripotent	ADJ
bptjm-29	238	36	,	,	PUNCT
bptjm-29	238	37	or	or	CCONJ
bptjm-29	238	38	capable	capable	ADJ
bptjm-29	238	39	of	of	ADP
bptjm-29	238	40	giving	give	VERB
bptjm-29	238	41	rise	rise	NOUN
bptjm-29	238	42	to	to	ADP
bptjm-29	238	43	a	a	DET
bptjm-29	238	44	variety	variety	NOUN
bptjm-29	238	45	of	of	ADP
bptjm-29	238	46	cell	cell	NOUN
bptjm-29	238	47	types	type	NOUN
bptjm-29	238	48	not	not	PART
bptjm-29	238	49	limited	limit	VERB
bptjm-29	238	50	to	to	ADP
bptjm-29	238	51	their	their	PRON
bptjm-29	238	52	organ	organ	NOUN
bptjm-29	238	53	or	or	CCONJ
bptjm-29	238	54	tissue	tissue	NOUN
bptjm-29	238	55	of	of	ADP
bptjm-29	238	56	residence	residence	NOUN
bptjm-29	238	57	.	.	PUNCT
bptjm-29	239	1	as	as	ADP
bptjm-29	239	2	a	a	DET
bptjm-29	239	3	result	result	NOUN
bptjm-29	239	4	,	,	PUNCT
bptjm-29	239	5	they	they	PRON
bptjm-29	239	6	are	be	AUX
bptjm-29	239	7	more	more	ADV
bptjm-29	239	8	versatile	versatile	ADJ
bptjm-29	239	9	and	and	CCONJ
bptjm-29	239	10	have	have	VERB
bptjm-29	239	11	the	the	DET
bptjm-29	239	12	capability	capability	NOUN
bptjm-29	239	13	of	of	ADP
bptjm-29	239	14	tissue	tissue	NOUN
bptjm-29	239	15	/	/	SYM
bptjm-29	239	16	organ	organ	NOUN
bptjm-29	239	17	regeneration	regeneration	NOUN
bptjm-29	239	18	and	and	CCONJ
bptjm-29	239	19	repair51	repair51	NOUN
bptjm-29	239	20	.	.	PUNCT
bptjm-29	240	1	however	however	ADV
bptjm-29	240	2	,	,	PUNCT
bptjm-29	240	3	embryonic	embryonic	ADJ
bptjm-29	240	4	stem	stem	NOUN
bptjm-29	240	5	cells	cell	NOUN
bptjm-29	240	6	have	have	VERB
bptjm-29	240	7	a	a	DET
bptjm-29	240	8	higher	high	ADJ
bptjm-29	240	9	probability	probability	NOUN
bptjm-29	240	10	of	of	ADP
bptjm-29	240	11	being	be	AUX
bptjm-29	240	12	rejected	reject	VERB
bptjm-29	240	13	by	by	ADP
bptjm-29	240	14	the	the	DET
bptjm-29	240	15	host	host	NOUN
bptjm-29	240	16	,	,	PUNCT
bptjm-29	240	17	and	and	CCONJ
bptjm-29	240	18	their	their	PRON
bptjm-29	240	19	use	use	NOUN
bptjm-29	240	20	is	be	AUX
bptjm-29	240	21	ethically	ethically	ADV
bptjm-29	240	22	controversial	controversial	ADJ
bptjm-29	240	23	by	by	ADP
bptjm-29	240	24	virtue	virtue	NOUN
bptjm-29	240	25	of	of	ADP
bptjm-29	240	26	the	the	DET
bptjm-29	240	27	berkeley	berkeley	PROPN
bptjm-29	240	28	pharma	pharma	PROPN
bptjm-29	240	29	tech	tech	NOUN
bptjm-29	240	30	journal	journal	NOUN
bptjm-29	240	31	of	of	ADP
bptjm-29	240	32	medicine	medicine	NOUN
bptjm-29	240	33	|	|	ADV
bptjm-29	240	34	86	86	NUM
bptjm-29	240	35	https://www.zotero.org/google-docs/?gwlwit	https://www.zotero.org/google-docs/?gwlwit	NOUN
bptjm-29	240	36	https://www.zotero.org/google-docs/?kmvrcs	https://www.zotero.org/google-docs/?kmvrc	NOUN
bptjm-29	241	1	https://www.zotero.org/google-docs/?3upw7h	https://www.zotero.org/google-docs/?3upw7h	PRON
bptjm-29	242	1	https://www.zotero.org/google-docs/?4lcndl	https://www.zotero.org/google-docs/?4lcndl	ADJ
bptjm-29	242	2	https://www.zotero.org/google-docs/?gvqryq	https://www.zotero.org/google-docs/?gvqryq	NOUN
bptjm-29	242	3	https://www.zotero.org/google-docs/?sknnii	https://www.zotero.org/google-docs/?sknnii	INTJ
bptjm-29	242	4	fact	fact	NOUN
bptjm-29	242	5	that	that	SCONJ
bptjm-29	242	6	the	the	DET
bptjm-29	242	7	destruction	destruction	NOUN
bptjm-29	242	8	of	of	ADP
bptjm-29	242	9	human	human	ADJ
bptjm-29	242	10	embryos	embryo	NOUN
bptjm-29	242	11	is	be	AUX
bptjm-29	242	12	necessary	necessary	ADJ
bptjm-29	242	13	in	in	ADP
bptjm-29	242	14	order	order	NOUN
bptjm-29	242	15	to	to	PART
bptjm-29	242	16	obtain	obtain	VERB
bptjm-29	242	17	escs52	escs52	ADV
bptjm-29	242	18	.	.	PUNCT
bptjm-29	243	1	6.3	6.3	NUM
bptjm-29	243	2	.	.	PUNCT
bptjm-29	244	1	induced	induce	VERB
bptjm-29	244	2	pluripotent	pluripotent	ADJ
bptjm-29	244	3	stem	stem	NOUN
bptjm-29	244	4	cells	cell	NOUN
bptjm-29	244	5	induced	induce	VERB
bptjm-29	244	6	pluripotent	pluripotent	ADJ
bptjm-29	244	7	stem	stem	NOUN
bptjm-29	244	8	cells	cell	NOUN
bptjm-29	244	9	are	be	AUX
bptjm-29	244	10	a	a	DET
bptjm-29	244	11	class	class	NOUN
bptjm-29	244	12	of	of	ADP
bptjm-29	244	13	pluripotent	pluripotent	ADJ
bptjm-29	244	14	cells	cell	NOUN
bptjm-29	244	15	that	that	PRON
bptjm-29	244	16	are	be	AUX
bptjm-29	244	17	commonly	commonly	ADV
bptjm-29	244	18	derived	derive	VERB
bptjm-29	244	19	from	from	ADP
bptjm-29	244	20	blood	blood	NOUN
bptjm-29	244	21	or	or	CCONJ
bptjm-29	244	22	skin	skin	NOUN
bptjm-29	244	23	cells	cell	NOUN
bptjm-29	244	24	and	and	CCONJ
bptjm-29	244	25	have	have	AUX
bptjm-29	244	26	been	be	AUX
bptjm-29	244	27	genetically	genetically	ADV
bptjm-29	244	28	engineered	engineer	VERB
bptjm-29	244	29	into	into	ADP
bptjm-29	244	30	an	an	DET
bptjm-29	244	31	embryonic	embryonic	ADJ
bptjm-29	244	32	-	-	PUNCT
bptjm-29	244	33	like	like	ADJ
bptjm-29	244	34	state	state	NOUN
bptjm-29	244	35	in	in	ADP
bptjm-29	244	36	order	order	NOUN
bptjm-29	244	37	to	to	PART
bptjm-29	244	38	behave	behave	VERB
bptjm-29	244	39	as	as	ADP
bptjm-29	244	40	escs53	escs53	NOUN
bptjm-29	244	41	.	.	PUNCT
bptjm-29	245	1	mesenchymal	mesenchymal	ADJ
bptjm-29	245	2	stem	stem	NOUN
bptjm-29	245	3	cells	cell	NOUN
bptjm-29	245	4	,	,	PUNCT
bptjm-29	245	5	the	the	DET
bptjm-29	245	6	subject	subject	NOUN
bptjm-29	245	7	of	of	ADP
bptjm-29	245	8	this	this	DET
bptjm-29	245	9	paper	paper	NOUN
bptjm-29	245	10	,	,	PUNCT
bptjm-29	245	11	are	be	AUX
bptjm-29	245	12	a	a	DET
bptjm-29	245	13	subgroup	subgroup	NOUN
bptjm-29	245	14	of	of	ADP
bptjm-29	245	15	adult	adult	NOUN
bptjm-29	245	16	multipotent	multipotent	NOUN
bptjm-29	245	17	stromal	stromal	ADJ
bptjm-29	245	18	cells	cell	NOUN
bptjm-29	245	19	that	that	PRON
bptjm-29	245	20	are	be	AUX
bptjm-29	245	21	derived	derive	VERB
bptjm-29	245	22	from	from	ADP
bptjm-29	245	23	adipose	adipose	ADJ
bptjm-29	245	24	tissue	tissue	NOUN
bptjm-29	245	25	,	,	PUNCT
bptjm-29	245	26	umbilical	umbilical	ADJ
bptjm-29	245	27	cord	cord	NOUN
bptjm-29	245	28	tissue	tissue	NOUN
bptjm-29	245	29	,	,	PUNCT
bptjm-29	245	30	amniotic	amniotic	PROPN
bptjm-29	245	31	�	�	PROPN
bptjm-29	245	32	uid	uid	ADJ
bptjm-29	245	33	,	,	PUNCT
bptjm-29	245	34	and	and	CCONJ
bptjm-29	245	35	bone	bone	NOUN
bptjm-29	245	36	marrow	marrow	NOUN
bptjm-29	245	37	,	,	PUNCT
bptjm-29	245	38	and	and	CCONJ
bptjm-29	245	39	have	have	VERB
bptjm-29	245	40	the	the	DET
bptjm-29	245	41	capacity	capacity	NOUN
bptjm-29	245	42	to	to	PART
bptjm-29	245	43	di	di	VERB
bptjm-29	245	44	�	�	PROPN
bptjm-29	245	45	erentiate	erentiate	NOUN
bptjm-29	245	46	into	into	ADP
bptjm-29	245	47	numerous	numerous	ADJ
bptjm-29	245	48	cell	cell	NOUN
bptjm-29	245	49	lines54	lines54	NOUN
bptjm-29	245	50	.	.	PUNCT
bptjm-29	246	1	stromal	stromal	ADJ
bptjm-29	246	2	cells	cell	NOUN
bptjm-29	246	3	comprise	comprise	VERB
bptjm-29	246	4	the	the	DET
bptjm-29	246	5	connective	connective	ADJ
bptjm-29	246	6	tissues	tissue	NOUN
bptjm-29	246	7	that	that	PRON
bptjm-29	246	8	surround	surround	VERB
bptjm-29	246	9	bodily	bodily	ADJ
bptjm-29	246	10	tissues	tissue	NOUN
bptjm-29	246	11	and	and	CCONJ
bptjm-29	246	12	organs	organ	NOUN
bptjm-29	246	13	and	and	CCONJ
bptjm-29	246	14	are	be	AUX
bptjm-29	246	15	separate	separate	ADJ
bptjm-29	246	16	from	from	ADP
bptjm-29	246	17	the	the	DET
bptjm-29	246	18	stroma	stroma	PROPN
bptjm-29	246	19	.	.	PUNCT
bptjm-29	247	1	table	table	NOUN
bptjm-29	247	2	2	2	NUM
bptjm-29	247	3	.	.	PUNCT
bptjm-29	248	1	a	a	DET
bptjm-29	248	2	comparison	comparison	NOUN
bptjm-29	248	3	of	of	ADP
bptjm-29	248	4	adult	adult	NOUN
bptjm-29	248	5	,	,	PUNCT
bptjm-29	248	6	embryonic	embryonic	ADJ
bptjm-29	248	7	,	,	PUNCT
bptjm-29	248	8	induced	induced	ADJ
bptjm-29	248	9	pluripotent	pluripotent	NOUN
bptjm-29	248	10	,	,	PUNCT
bptjm-29	248	11	and	and	CCONJ
bptjm-29	248	12	mesenchymal	mesenchymal	NOUN
bptjm-29	248	13	stem	stem	NOUN
bptjm-29	248	14	cells	cell	NOUN
bptjm-29	248	15	stem	stem	VERB
bptjm-29	248	16	cells	cell	NOUN
bptjm-29	248	17	are	be	AUX
bptjm-29	248	18	especially	especially	ADV
bptjm-29	248	19	signi	signi	ADJ
bptjm-29	248	20	�	�	NOUN
bptjm-29	248	21	cant	cant	NOUN
bptjm-29	248	22	and	and	CCONJ
bptjm-29	248	23	have	have	AUX
bptjm-29	248	24	been	be	AUX
bptjm-29	248	25	the	the	DET
bptjm-29	248	26	subject	subject	NOUN
bptjm-29	248	27	of	of	ADP
bptjm-29	248	28	intensive	intensive	ADJ
bptjm-29	248	29	study	study	NOUN
bptjm-29	248	30	due	due	ADP
bptjm-29	248	31	to	to	ADP
bptjm-29	248	32	the	the	DET
bptjm-29	248	33	fact	fact	NOUN
bptjm-29	248	34	that	that	SCONJ
bptjm-29	248	35	they	they	PRON
bptjm-29	248	36	are	be	AUX
bptjm-29	248	37	the	the	DET
bptjm-29	248	38	only	only	ADJ
bptjm-29	248	39	cell	cell	NOUN
bptjm-29	248	40	that	that	PRON
bptjm-29	248	41	can	can	AUX
bptjm-29	248	42	naturally	naturally	ADV
bptjm-29	248	43	develop	develop	VERB
bptjm-29	248	44	and	and	CCONJ
bptjm-29	248	45	di	di	NOUN
bptjm-29	248	46	�	�	PROPN
bptjm-29	248	47	erentiate	erentiate	NOUN
bptjm-29	248	48	into	into	ADP
bptjm-29	248	49	varying	vary	VERB
bptjm-29	248	50	cell	cell	NOUN
bptjm-29	248	51	types	type	NOUN
bptjm-29	248	52	primarily	primarily	ADV
bptjm-29	248	53	through	through	ADP
bptjm-29	248	54	the	the	DET
bptjm-29	248	55	autocrine	autocrine	NOUN
bptjm-29	248	56	production	production	NOUN
bptjm-29	248	57	of	of	ADP
bptjm-29	248	58	immunomodulatory	immunomodulatory	ADJ
bptjm-29	248	59	molecules	molecule	NOUN
bptjm-29	248	60	,	,	PUNCT
bptjm-29	248	61	bioactive	bioactive	ADJ
bptjm-29	248	62	molecules	molecule	NOUN
bptjm-29	248	63	stored	store	VERB
bptjm-29	248	64	within	within	ADP
bptjm-29	248	65	extracellular	extracellular	ADJ
bptjm-29	248	66	vesicles	vesicle	NOUN
bptjm-29	248	67	,	,	PUNCT
bptjm-29	248	68	and	and	CCONJ
bptjm-29	248	69	growth	growth	NOUN
bptjm-29	248	70	factors	factor	NOUN
bptjm-29	248	71	such	such	ADJ
bptjm-29	248	72	as	as	ADP
bptjm-29	248	73	the	the	DET
bptjm-29	248	74	vascular	vascular	ADJ
bptjm-29	248	75	endothelial	endothelial	ADJ
bptjm-29	248	76	growth	growth	NOUN
bptjm-29	248	77	factor	factor	NOUN
bptjm-29	248	78	(	(	PUNCT
bptjm-29	248	79	vegf)47	vegf)47	PROPN
bptjm-29	248	80	.	.	PUNCT
bptjm-29	249	1	as	as	ADP
bptjm-29	249	2	a	a	DET
bptjm-29	249	3	result	result	NOUN
bptjm-29	249	4	,	,	PUNCT
bptjm-29	249	5	stem	stem	NOUN
bptjm-29	249	6	cells	cell	NOUN
bptjm-29	249	7	could	could	AUX
bptjm-29	249	8	,	,	PUNCT
bptjm-29	249	9	theoretically	theoretically	ADV
bptjm-29	249	10	,	,	PUNCT
bptjm-29	249	11	limitlessly	limitlessly	ADV
bptjm-29	249	12	participate	participate	VERB
bptjm-29	249	13	in	in	ADP
bptjm-29	249	14	cell	cell	NOUN
bptjm-29	249	15	division	division	NOUN
bptjm-29	249	16	in	in	ADP
bptjm-29	249	17	order	order	NOUN
bptjm-29	249	18	to	to	PART
bptjm-29	249	19	replace	replace	VERB
bptjm-29	249	20	cells	cell	NOUN
bptjm-29	249	21	within	within	ADP
bptjm-29	249	22	damaged	damage	VERB
bptjm-29	249	23	tissue55	tissue55	NOUN
bptjm-29	249	24	.	.	PUNCT
bptjm-29	250	1	they	they	PRON
bptjm-29	250	2	have	have	VERB
bptjm-29	250	3	the	the	DET
bptjm-29	250	4	unique	unique	ADJ
bptjm-29	250	5	ability	ability	NOUN
bptjm-29	250	6	to	to	PART
bptjm-29	250	7	di	di	VERB
bptjm-29	250	8	�	�	PROPN
bptjm-29	250	9	erentiate	erentiate	NOUN
bptjm-29	250	10	in	in	ADP
bptjm-29	250	11	response	response	NOUN
bptjm-29	250	12	to	to	ADP
bptjm-29	250	13	the	the	DET
bptjm-29	250	14	microenvironment	microenvironment	NOUN
bptjm-29	250	15	in	in	ADP
bptjm-29	250	16	which	which	PRON
bptjm-29	250	17	they	they	PRON
bptjm-29	250	18	have	have	AUX
bptjm-29	250	19	been	be	AUX
bptjm-29	250	20	directed	direct	VERB
bptjm-29	250	21	berkeley	berkeley	PROPN
bptjm-29	250	22	pharma	pharma	PROPN
bptjm-29	250	23	tech	tech	NOUN
bptjm-29	250	24	journal	journal	NOUN
bptjm-29	250	25	of	of	ADP
bptjm-29	250	26	medicine	medicine	NOUN
bptjm-29	250	27	|	|	ADV
bptjm-29	250	28	87	87	NUM
bptjm-29	250	29	https://www.zotero.org/google-docs/?xaaej1	https://www.zotero.org/google-docs/?xaaej1	VERB
bptjm-29	250	30	https://www.zotero.org/google-docs/?gmrvek	https://www.zotero.org/google-docs/?gmrvek	PROPN
bptjm-29	250	31	https://www.zotero.org/google-docs/?hgkexh	https://www.zotero.org/google-docs/?hgkexh	PROPN
bptjm-29	250	32	https://www.zotero.org/google-docs/?dpwwmn	https://www.zotero.org/google-docs/?dpwwmn	PROPN
bptjm-29	250	33	https://www.zotero.org/google-docs/?avsmik	https://www.zotero.org/google-docs/?avsmik	PROPN
bptjm-29	250	34	toward56	toward56	PROPN
bptjm-29	250	35	.	.	PUNCT
bptjm-29	251	1	it	it	PRON
bptjm-29	251	2	is	be	AUX
bptjm-29	251	3	also	also	ADV
bptjm-29	251	4	important	important	ADJ
bptjm-29	251	5	to	to	PART
bptjm-29	251	6	consider	consider	VERB
bptjm-29	251	7	,	,	PUNCT
bptjm-29	251	8	though	though	ADV
bptjm-29	251	9	,	,	PUNCT
bptjm-29	251	10	that	that	PRON
bptjm-29	251	11	stem	stem	NOUN
bptjm-29	251	12	cells	cell	NOUN
bptjm-29	251	13	need	need	VERB
bptjm-29	251	14	to	to	PART
bptjm-29	251	15	be	be	AUX
bptjm-29	251	16	carefully	carefully	ADV
bptjm-29	251	17	selected	select	VERB
bptjm-29	251	18	according	accord	VERB
bptjm-29	251	19	to	to	ADP
bptjm-29	251	20	their	their	PRON
bptjm-29	251	21	biological	biological	ADJ
bptjm-29	251	22	capacity	capacity	NOUN
bptjm-29	251	23	to	to	PART
bptjm-29	251	24	survive	survive	VERB
bptjm-29	251	25	within	within	ADP
bptjm-29	251	26	the	the	DET
bptjm-29	251	27	host	host	NOUN
bptjm-29	251	28	organism	organism	NOUN
bptjm-29	251	29	(	(	PUNCT
bptjm-29	251	30	where	where	SCONJ
bptjm-29	251	31	the	the	DET
bptjm-29	251	32	cells	cell	NOUN
bptjm-29	251	33	are	be	AUX
bptjm-29	251	34	transplanted	transplant	VERB
bptjm-29	251	35	)	)	PUNCT
bptjm-29	251	36	,	,	PUNCT
bptjm-29	251	37	and	and	CCONJ
bptjm-29	251	38	their	their	PRON
bptjm-29	251	39	ability	ability	NOUN
bptjm-29	251	40	to	to	PART
bptjm-29	251	41	di	di	VERB
bptjm-29	251	42	�	�	PROPN
bptjm-29	251	43	erentiate	erentiate	NOUN
bptjm-29	251	44	and	and	CCONJ
bptjm-29	251	45	migrate	migrate	VERB
bptjm-29	251	46	to	to	ADP
bptjm-29	251	47	various	various	ADJ
bptjm-29	251	48	tissues	tissue	NOUN
bptjm-29	251	49	.	.	PUNCT
bptjm-29	252	1	the	the	DET
bptjm-29	252	2	upsides	upside	NOUN
bptjm-29	252	3	and	and	CCONJ
bptjm-29	252	4	downsides	downside	NOUN
bptjm-29	252	5	of	of	ADP
bptjm-29	252	6	each	each	DET
bptjm-29	252	7	form	form	NOUN
bptjm-29	252	8	of	of	ADP
bptjm-29	252	9	stem	stem	NOUN
bptjm-29	252	10	cells	cell	NOUN
bptjm-29	252	11	must	must	AUX
bptjm-29	252	12	be	be	AUX
bptjm-29	252	13	evaluated	evaluate	VERB
bptjm-29	252	14	upon	upon	SCONJ
bptjm-29	252	15	consideration	consideration	NOUN
bptjm-29	252	16	for	for	ADP
bptjm-29	252	17	disease	disease	NOUN
bptjm-29	252	18	treatment	treatment	NOUN
bptjm-29	252	19	or	or	CCONJ
bptjm-29	252	20	regeneration	regeneration	NOUN
bptjm-29	252	21	.	.	PUNCT
bptjm-29	253	1	on	on	ADP
bptjm-29	253	2	an	an	DET
bptjm-29	253	3	interdisciplinary	interdisciplinary	ADJ
bptjm-29	253	4	scale	scale	NOUN
bptjm-29	253	5	,	,	PUNCT
bptjm-29	253	6	however	however	ADV
bptjm-29	253	7	,	,	PUNCT
bptjm-29	253	8	because	because	SCONJ
bptjm-29	253	9	the	the	DET
bptjm-29	253	10	treatment	treatment	NOUN
bptjm-29	253	11	options	option	NOUN
bptjm-29	253	12	for	for	ADP
bptjm-29	253	13	neurological	neurological	ADJ
bptjm-29	253	14	diseases	disease	NOUN
bptjm-29	253	15	remain	remain	VERB
bptjm-29	253	16	heavily	heavily	ADV
bptjm-29	253	17	limited	limited	ADJ
bptjm-29	253	18	and	and	CCONJ
bptjm-29	253	19	drug	drug	NOUN
bptjm-29	253	20	approval	approval	NOUN
bptjm-29	253	21	rates	rate	NOUN
bptjm-29	253	22	remain	remain	VERB
bptjm-29	253	23	poor	poor	ADJ
bptjm-29	253	24	in	in	ADP
bptjm-29	253	25	comparison	comparison	NOUN
bptjm-29	253	26	to	to	ADP
bptjm-29	253	27	other	other	ADJ
bptjm-29	253	28	therapeutic	therapeutic	ADJ
bptjm-29	253	29	areas	area	NOUN
bptjm-29	253	30	,	,	PUNCT
bptjm-29	253	31	the	the	DET
bptjm-29	253	32	implementation	implementation	NOUN
bptjm-29	253	33	of	of	ADP
bptjm-29	253	34	stem	stem	NOUN
bptjm-29	253	35	cells	cell	NOUN
bptjm-29	253	36	carries	carry	VERB
bptjm-29	253	37	immense	immense	ADJ
bptjm-29	253	38	potential	potential	NOUN
bptjm-29	253	39	for	for	ADP
bptjm-29	253	40	patients	patient	NOUN
bptjm-29	253	41	a	a	DET
bptjm-29	253	42	�	�	PROPN
bptjm-29	253	43	icted	icte	VERB
bptjm-29	253	44	with	with	ADP
bptjm-29	253	45	disorders	disorder	NOUN
bptjm-29	253	46	such	such	ADJ
bptjm-29	253	47	as	as	ADP
bptjm-29	253	48	als	al	NOUN
bptjm-29	253	49	.	.	PUNCT
bptjm-29	254	1	furthermore	furthermore	ADV
bptjm-29	254	2	,	,	PUNCT
bptjm-29	254	3	numerous	numerous	ADJ
bptjm-29	254	4	degenerative	degenerative	ADJ
bptjm-29	254	5	diseases	disease	NOUN
bptjm-29	254	6	involve	involve	VERB
bptjm-29	254	7	an	an	DET
bptjm-29	254	8	improper	improper	ADJ
bptjm-29	254	9	functioning	functioning	NOUN
bptjm-29	254	10	or	or	CCONJ
bptjm-29	254	11	loss	loss	NOUN
bptjm-29	254	12	of	of	ADP
bptjm-29	254	13	specialized	specialized	ADJ
bptjm-29	254	14	cells	cell	NOUN
bptjm-29	254	15	within	within	ADP
bptjm-29	254	16	the	the	DET
bptjm-29	254	17	body	body	NOUN
bptjm-29	254	18	and	and	CCONJ
bptjm-29	254	19	there	there	PRON
bptjm-29	254	20	is	be	VERB
bptjm-29	254	21	an	an	DET
bptjm-29	254	22	imbalance	imbalance	NOUN
bptjm-29	254	23	between	between	ADP
bptjm-29	254	24	the	the	DET
bptjm-29	254	25	supply	supply	NOUN
bptjm-29	254	26	and	and	CCONJ
bptjm-29	254	27	demand	demand	NOUN
bptjm-29	254	28	of	of	ADP
bptjm-29	254	29	potential	potential	ADJ
bptjm-29	254	30	donors	donor	NOUN
bptjm-29	254	31	and	and	CCONJ
bptjm-29	254	32	their	their	PRON
bptjm-29	254	33	cells	cell	NOUN
bptjm-29	254	34	within	within	ADP
bptjm-29	254	35	their	their	PRON
bptjm-29	254	36	organs	organ	NOUN
bptjm-29	254	37	or	or	CCONJ
bptjm-29	254	38	tissues	tissue	NOUN
bptjm-29	254	39	.	.	PUNCT
bptjm-29	255	1	speci	speci	PROPN
bptjm-29	255	2	�	�	PROPN
bptjm-29	255	3	cally	cally	ADV
bptjm-29	255	4	,	,	PUNCT
bptjm-29	255	5	the	the	DET
bptjm-29	255	6	supply	supply	NOUN
bptjm-29	255	7	of	of	ADP
bptjm-29	255	8	donors	donor	NOUN
bptjm-29	255	9	is	be	AUX
bptjm-29	255	10	currently	currently	ADV
bptjm-29	255	11	unable	unable	ADJ
bptjm-29	255	12	to	to	PART
bptjm-29	255	13	ful	ful	VERB
bptjm-29	255	14	�	�	PROPN
bptjm-29	255	15	ll	ll	NOUN
bptjm-29	255	16	the	the	DET
bptjm-29	255	17	demand	demand	NOUN
bptjm-29	255	18	of	of	ADP
bptjm-29	255	19	replacement	replacement	NOUN
bptjm-29	255	20	cells	cell	NOUN
bptjm-29	255	21	.	.	PUNCT
bptjm-29	256	1	as	as	ADP
bptjm-29	256	2	such	such	ADJ
bptjm-29	256	3	,	,	PUNCT
bptjm-29	256	4	stem	stem	NOUN
bptjm-29	256	5	cells	cell	NOUN
bptjm-29	256	6	could	could	AUX
bptjm-29	256	7	serve	serve	VERB
bptjm-29	256	8	as	as	ADP
bptjm-29	256	9	a	a	DET
bptjm-29	256	10	solution	solution	NOUN
bptjm-29	256	11	,	,	PUNCT
bptjm-29	256	12	continuously	continuously	ADV
bptjm-29	256	13	producing	produce	VERB
bptjm-29	256	14	viable	viable	ADJ
bptjm-29	256	15	cells	cell	NOUN
bptjm-29	256	16	that	that	PRON
bptjm-29	256	17	could	could	AUX
bptjm-29	256	18	replace	replace	VERB
bptjm-29	256	19	damaged	damage	VERB
bptjm-29	256	20	or	or	CCONJ
bptjm-29	256	21	injured	injure	VERB
bptjm-29	256	22	tissues	tissue	NOUN
bptjm-29	256	23	and	and	CCONJ
bptjm-29	256	24	thus	thus	ADV
bptjm-29	256	25	address	address	VERB
bptjm-29	256	26	a	a	DET
bptjm-29	256	27	number	number	NOUN
bptjm-29	256	28	of	of	ADP
bptjm-29	256	29	a	a	DET
bptjm-29	256	30	�	�	NOUN
bptjm-29	256	31	ictions55	ictions55	NOUN
bptjm-29	256	32	.	.	PUNCT
bptjm-29	257	1	to	to	ADP
bptjm-29	257	2	date	date	NOUN
bptjm-29	257	3	,	,	PUNCT
bptjm-29	257	4	stem	stem	NOUN
bptjm-29	257	5	cells	cell	NOUN
bptjm-29	257	6	have	have	AUX
bptjm-29	257	7	been	be	AUX
bptjm-29	257	8	implemented	implement	VERB
bptjm-29	257	9	for	for	ADP
bptjm-29	257	10	the	the	DET
bptjm-29	257	11	treatment	treatment	NOUN
bptjm-29	257	12	of	of	ADP
bptjm-29	257	13	diseases	disease	NOUN
bptjm-29	257	14	such	such	ADJ
bptjm-29	257	15	as	as	ADP
bptjm-29	257	16	amyloidosis	amyloidosis	NOUN
bptjm-29	257	17	,	,	PUNCT
bptjm-29	257	18	germ	germ	NOUN
bptjm-29	257	19	cell	cell	NOUN
bptjm-29	257	20	tumors	tumor	NOUN
bptjm-29	257	21	,	,	PUNCT
bptjm-29	257	22	and	and	CCONJ
bptjm-29	257	23	certain	certain	ADJ
bptjm-29	257	24	cancers	cancer	NOUN
bptjm-29	257	25	through	through	ADP
bptjm-29	257	26	autologous	autologous	ADJ
bptjm-29	257	27	(	(	PUNCT
bptjm-29	257	28	obtained	obtain	VERB
bptjm-29	257	29	from	from	ADP
bptjm-29	257	30	the	the	DET
bptjm-29	257	31	same	same	ADJ
bptjm-29	257	32	individual	individual	NOUN
bptjm-29	257	33	)	)	PUNCT
bptjm-29	257	34	and	and	CCONJ
bptjm-29	257	35	allogenic	allogenic	PROPN
bptjm-29	257	36	(	(	PUNCT
bptjm-29	257	37	obtained	obtain	VERB
bptjm-29	257	38	from	from	ADP
bptjm-29	257	39	a	a	DET
bptjm-29	257	40	source	source	NOUN
bptjm-29	257	41	outside	outside	ADP
bptjm-29	257	42	the	the	DET
bptjm-29	257	43	individual	individual	NOUN
bptjm-29	257	44	,	,	PUNCT
bptjm-29	257	45	such	such	ADJ
bptjm-29	257	46	as	as	ADP
bptjm-29	257	47	a	a	DET
bptjm-29	257	48	donor	donor	NOUN
bptjm-29	257	49	)	)	PUNCT
bptjm-29	257	50	transplantation	transplantation	NOUN
bptjm-29	257	51	.	.	PUNCT
bptjm-29	258	1	with	with	ADP
bptjm-29	258	2	cancers	cancer	NOUN
bptjm-29	258	3	,	,	PUNCT
bptjm-29	258	4	speci	speci	PROPN
bptjm-29	258	5	�	�	NOUN
bptjm-29	258	6	cally	cally	ADV
bptjm-29	258	7	,	,	PUNCT
bptjm-29	258	8	stem	stem	NOUN
bptjm-29	258	9	cells	cell	NOUN
bptjm-29	258	10	have	have	AUX
bptjm-29	258	11	been	be	AUX
bptjm-29	258	12	implemented	implement	VERB
bptjm-29	258	13	to	to	PART
bptjm-29	258	14	replace	replace	VERB
bptjm-29	258	15	cells	cell	NOUN
bptjm-29	258	16	that	that	PRON
bptjm-29	258	17	have	have	AUX
bptjm-29	258	18	been	be	AUX
bptjm-29	258	19	adversely	adversely	ADV
bptjm-29	258	20	impacted	impact	VERB
bptjm-29	258	21	by	by	ADP
bptjm-29	258	22	the	the	DET
bptjm-29	258	23	cancer	cancer	NOUN
bptjm-29	258	24	pathogenesis	pathogenesis	NOUN
bptjm-29	258	25	itself	itself	PRON
bptjm-29	258	26	or	or	CCONJ
bptjm-29	258	27	chemotherapy	chemotherapy	NOUN
bptjm-29	258	28	.	.	PUNCT
bptjm-29	259	1	while	while	SCONJ
bptjm-29	259	2	stem	stem	NOUN
bptjm-29	259	3	cells	cell	NOUN
bptjm-29	259	4	are	be	AUX
bptjm-29	259	5	continually	continually	ADV
bptjm-29	259	6	being	be	AUX
bptjm-29	259	7	utilized	utilize	VERB
bptjm-29	259	8	for	for	ADP
bptjm-29	259	9	the	the	DET
bptjm-29	259	10	treatment	treatment	NOUN
bptjm-29	259	11	and	and	CCONJ
bptjm-29	259	12	maintenance	maintenance	NOUN
bptjm-29	259	13	of	of	ADP
bptjm-29	259	14	a	a	DET
bptjm-29	259	15	myriad	myriad	NOUN
bptjm-29	259	16	of	of	ADP
bptjm-29	259	17	diseases	disease	NOUN
bptjm-29	259	18	,	,	PUNCT
bptjm-29	259	19	further	further	ADJ
bptjm-29	259	20	research	research	NOUN
bptjm-29	259	21	is	be	AUX
bptjm-29	259	22	necessary	necessary	ADJ
bptjm-29	259	23	to	to	PART
bptjm-29	259	24	fully	fully	ADV
bptjm-29	259	25	elucidate	elucidate	VERB
bptjm-29	259	26	the	the	DET
bptjm-29	259	27	pathogenetic	pathogenetic	ADJ
bptjm-29	259	28	mechanisms	mechanism	NOUN
bptjm-29	259	29	by	by	ADP
bptjm-29	259	30	which	which	PRON
bptjm-29	259	31	stem	stem	NOUN
bptjm-29	259	32	cells	cell	NOUN
bptjm-29	259	33	function	function	NOUN
bptjm-29	259	34	,	,	PUNCT
bptjm-29	259	35	to	to	PART
bptjm-29	259	36	properly	properly	ADV
bptjm-29	259	37	isolate	isolate	VERB
bptjm-29	259	38	and	and	CCONJ
bptjm-29	259	39	identify	identify	VERB
bptjm-29	259	40	stem	stem	NOUN
bptjm-29	259	41	cells	cell	NOUN
bptjm-29	259	42	to	to	PART
bptjm-29	259	43	avoid	avoid	VERB
bptjm-29	259	44	immunological	immunological	ADJ
bptjm-29	259	45	rejection	rejection	NOUN
bptjm-29	259	46	to	to	ADP
bptjm-29	259	47	the	the	DET
bptjm-29	259	48	greatest	great	ADJ
bptjm-29	259	49	extent	extent	NOUN
bptjm-29	259	50	possible	possible	ADJ
bptjm-29	259	51	,	,	PUNCT
bptjm-29	259	52	and	and	CCONJ
bptjm-29	259	53	to	to	PART
bptjm-29	259	54	address	address	VERB
bptjm-29	259	55	the	the	DET
bptjm-29	259	56	predisposition	predisposition	NOUN
bptjm-29	259	57	of	of	ADP
bptjm-29	259	58	induced	induce	VERB
bptjm-29	259	59	pluripotent	pluripotent	ADJ
bptjm-29	259	60	stem	stem	NOUN
bptjm-29	259	61	cells	cell	NOUN
bptjm-29	259	62	to	to	ADP
bptjm-29	259	63	tumorigenesis	tumorigenesis	VERB
bptjm-29	259	64	,	,	PUNCT
bptjm-29	259	65	or	or	CCONJ
bptjm-29	259	66	the	the	DET
bptjm-29	259	67	formation	formation	NOUN
bptjm-29	259	68	of	of	ADP
bptjm-29	259	69	tumors	tumor	NOUN
bptjm-29	259	70	in	in	ADP
bptjm-29	259	71	vivo57	vivo57	NOUN
bptjm-29	259	72	,	,	PUNCT
bptjm-29	259	73	55	55	NUM
bptjm-29	259	74	.	.	PUNCT
bptjm-29	260	1	6.4	6.4	NUM
bptjm-29	260	2	.	.	PUNCT
bptjm-29	261	1	mesenchymal	mesenchymal	ADJ
bptjm-29	261	2	stem	stem	NOUN
bptjm-29	261	3	cells	cell	NOUN
bptjm-29	261	4	mesenchymal	mesenchymal	ADJ
bptjm-29	261	5	stem	stem	NOUN
bptjm-29	261	6	cells	cell	NOUN
bptjm-29	261	7	(	(	PUNCT
bptjm-29	261	8	mscs	msc	NOUN
bptjm-29	261	9	)	)	PUNCT
bptjm-29	261	10	are	be	AUX
bptjm-29	261	11	a	a	DET
bptjm-29	261	12	class	class	NOUN
bptjm-29	261	13	of	of	ADP
bptjm-29	261	14	stem	stem	NOUN
bptjm-29	261	15	cells	cell	NOUN
bptjm-29	261	16	multipotent	multipotent	NOUN
bptjm-29	261	17	and	and	CCONJ
bptjm-29	261	18	non	non	ADJ
bptjm-29	261	19	-	-	ADJ
bptjm-29	261	20	hematopoietic	hematopoietic	ADJ
bptjm-29	261	21	stromal	stromal	ADJ
bptjm-29	261	22	cells	cell	NOUN
bptjm-29	261	23	which	which	PRON
bptjm-29	261	24	are	be	AUX
bptjm-29	261	25	conventionally	conventionally	ADV
bptjm-29	261	26	derived	derive	VERB
bptjm-29	261	27	from	from	ADP
bptjm-29	261	28	adult	adult	NOUN
bptjm-29	261	29	and	and	CCONJ
bptjm-29	261	30	fetal	fetal	ADJ
bptjm-29	261	31	tissue	tissue	NOUN
bptjm-29	261	32	,	,	PUNCT
bptjm-29	261	33	such	such	ADJ
bptjm-29	261	34	as	as	ADP
bptjm-29	261	35	skeletal	skeletal	ADJ
bptjm-29	261	36	muscle	muscle	NOUN
bptjm-29	261	37	,	,	PUNCT
bptjm-29	261	38	the	the	DET
bptjm-29	261	39	placenta	placenta	NOUN
bptjm-29	261	40	,	,	PUNCT
bptjm-29	261	41	blood	blood	NOUN
bptjm-29	261	42	,	,	PUNCT
bptjm-29	261	43	adipose	adipose	NOUN
bptjm-29	261	44	,	,	PUNCT
bptjm-29	261	45	and	and	CCONJ
bptjm-29	261	46	the	the	DET
bptjm-29	261	47	umbilical	umbilical	ADJ
bptjm-29	261	48	cord7	cord7	NOUN
bptjm-29	261	49	.	.	PUNCT
bptjm-29	262	1	mscs	msc	NOUN
bptjm-29	262	2	have	have	AUX
bptjm-29	262	3	been	be	AUX
bptjm-29	262	4	demonstrated	demonstrate	VERB
bptjm-29	262	5	to	to	PART
bptjm-29	262	6	take	take	VERB
bptjm-29	262	7	residence	residence	NOUN
bptjm-29	262	8	berkeley	berkeley	PROPN
bptjm-29	262	9	pharma	pharma	PROPN
bptjm-29	262	10	tech	tech	NOUN
bptjm-29	262	11	journal	journal	NOUN
bptjm-29	262	12	of	of	ADP
bptjm-29	262	13	medicine	medicine	NOUN
bptjm-29	262	14	|	|	ADV
bptjm-29	262	15	88	88	NUM
bptjm-29	262	16	https://www.zotero.org/google-docs/?m9egga	https://www.zotero.org/google-docs/?m9egga	ADJ
bptjm-29	262	17	https://www.zotero.org/google-docs/?bopw39	https://www.zotero.org/google-docs/?bopw39	NOUN
bptjm-29	262	18	https://www.zotero.org/google-docs/?evkrhb	https://www.zotero.org/google-docs/?evkrhb	NOUN
bptjm-29	262	19	https://www.zotero.org/google-docs/?chmphx	https://www.zotero.org/google-docs/?chmphx	NOUN
bptjm-29	262	20	https://www.zotero.org/google-docs/?efbkl6	https://www.zotero.org/google-docs/?efbkl6	PROPN
bptjm-29	262	21	within	within	ADP
bptjm-29	262	22	most	most	ADJ
bptjm-29	262	23	connective	connective	ADJ
bptjm-29	262	24	tissues	tissue	NOUN
bptjm-29	262	25	in	in	ADP
bptjm-29	262	26	the	the	DET
bptjm-29	262	27	human	human	ADJ
bptjm-29	262	28	body	body	NOUN
bptjm-29	262	29	.	.	PUNCT
bptjm-29	263	1	this	this	DET
bptjm-29	263	2	high	high	ADJ
bptjm-29	263	3	availability	availability	NOUN
bptjm-29	263	4	within	within	ADP
bptjm-29	263	5	human	human	ADJ
bptjm-29	263	6	tissues	tissue	NOUN
bptjm-29	263	7	makes	make	VERB
bptjm-29	263	8	mscs	msc	NOUN
bptjm-29	263	9	accessible	accessible	ADJ
bptjm-29	263	10	as	as	ADP
bptjm-29	263	11	a	a	DET
bptjm-29	263	12	disease	disease	NOUN
bptjm-29	263	13	therapeutic	therapeutic	ADJ
bptjm-29	263	14	.	.	PUNCT
bptjm-29	264	1	since	since	SCONJ
bptjm-29	264	2	mscs	msc	NOUN
bptjm-29	264	3	are	be	AUX
bptjm-29	264	4	multipotent	multipotent	ADJ
bptjm-29	264	5	,	,	PUNCT
bptjm-29	264	6	they	they	PRON
bptjm-29	264	7	have	have	VERB
bptjm-29	264	8	a	a	DET
bptjm-29	264	9	high	high	ADJ
bptjm-29	264	10	di	di	NOUN
bptjm-29	264	11	�	�	PROPN
bptjm-29	264	12	erentiation	erentiation	NOUN
bptjm-29	264	13	plasticity	plasticity	NOUN
bptjm-29	264	14	,	,	PUNCT
bptjm-29	264	15	or	or	CCONJ
bptjm-29	264	16	a	a	DET
bptjm-29	264	17	capability	capability	NOUN
bptjm-29	264	18	of	of	ADP
bptjm-29	264	19	trans	trans	PROPN
bptjm-29	264	20	-	-	PROPN
bptjm-29	264	21	di	di	NOUN
bptjm-29	264	22	�	�	PROPN
bptjm-29	264	23	erentiating	erentiate	VERB
bptjm-29	264	24	into	into	ADP
bptjm-29	264	25	multiple	multiple	ADJ
bptjm-29	264	26	specialized	specialized	ADJ
bptjm-29	264	27	cell	cell	NOUN
bptjm-29	264	28	types58	types58	NOUN
bptjm-29	264	29	.	.	PUNCT
bptjm-29	265	1	transdi	transdi	PROPN
bptjm-29	265	2	�	�	PROPN
bptjm-29	265	3	erentiation	erentiation	NOUN
bptjm-29	265	4	is	be	AUX
bptjm-29	265	5	the	the	DET
bptjm-29	265	6	process	process	NOUN
bptjm-29	265	7	by	by	ADP
bptjm-29	265	8	which	which	PRON
bptjm-29	265	9	a	a	DET
bptjm-29	265	10	cell	cell	NOUN
bptjm-29	265	11	can	can	AUX
bptjm-29	265	12	be	be	AUX
bptjm-29	265	13	made	make	VERB
bptjm-29	265	14	to	to	PART
bptjm-29	265	15	di	di	VERB
bptjm-29	265	16	�	�	PROPN
bptjm-29	265	17	erentiate	erentiate	NOUN
bptjm-29	265	18	from	from	ADP
bptjm-29	265	19	one	one	NUM
bptjm-29	265	20	cell	cell	NOUN
bptjm-29	265	21	type	type	NOUN
bptjm-29	265	22	into	into	ADP
bptjm-29	265	23	another	another	PRON
bptjm-29	265	24	through	through	ADP
bptjm-29	265	25	genetic	genetic	ADJ
bptjm-29	265	26	reprogramming	reprogramming	NOUN
bptjm-29	265	27	.	.	PUNCT
bptjm-29	266	1	for	for	ADP
bptjm-29	266	2	instance	instance	NOUN
bptjm-29	266	3	,	,	PUNCT
bptjm-29	266	4	they	they	PRON
bptjm-29	266	5	are	be	AUX
bptjm-29	266	6	able	able	ADJ
bptjm-29	266	7	to	to	PART
bptjm-29	266	8	di	di	VERB
bptjm-29	266	9	�	�	PROPN
bptjm-29	266	10	erentiate	erentiate	NOUN
bptjm-29	266	11	into	into	ADP
bptjm-29	266	12	nerve	nerve	NOUN
bptjm-29	266	13	,	,	PUNCT
bptjm-29	266	14	heart	heart	NOUN
bptjm-29	266	15	muscle	muscle	NOUN
bptjm-29	266	16	,	,	PUNCT
bptjm-29	266	17	liver	liver	NOUN
bptjm-29	266	18	,	,	PUNCT
bptjm-29	266	19	and	and	CCONJ
bptjm-29	266	20	endothelial	endothelial	ADJ
bptjm-29	266	21	cells	cell	NOUN
bptjm-29	266	22	,	,	PUNCT
bptjm-29	266	23	in	in	ADP
bptjm-29	266	24	addition	addition	NOUN
bptjm-29	266	25	to	to	ADP
bptjm-29	266	26	the	the	DET
bptjm-29	266	27	germ	germ	NOUN
bptjm-29	266	28	layers	layer	VERB
bptjm-29	266	29	the	the	DET
bptjm-29	266	30	ectoderm	ectoderm	NOUN
bptjm-29	266	31	,	,	PUNCT
bptjm-29	266	32	mesoderm	mesoderm	NOUN
bptjm-29	266	33	,	,	PUNCT
bptjm-29	266	34	and	and	CCONJ
bptjm-29	266	35	endoderm	endoderm	NOUN
bptjm-29	266	36	.	.	PUNCT
bptjm-29	267	1	furthermore	furthermore	ADV
bptjm-29	267	2	,	,	PUNCT
bptjm-29	267	3	mscs	msc	NOUN
bptjm-29	267	4	are	be	AUX
bptjm-29	267	5	capable	capable	ADJ
bptjm-29	267	6	of	of	ADP
bptjm-29	267	7	di	di	PROPN
bptjm-29	267	8	�	�	PROPN
bptjm-29	267	9	erentiating	erentiate	VERB
bptjm-29	267	10	into	into	ADP
bptjm-29	267	11	neural	neural	ADJ
bptjm-29	267	12	,	,	PUNCT
bptjm-29	267	13	glial	glial	ADJ
bptjm-29	267	14	,	,	PUNCT
bptjm-29	267	15	and	and	CCONJ
bptjm-29	267	16	astrocyte	astrocyte	ADJ
bptjm-29	267	17	-	-	PUNCT
bptjm-29	267	18	like	like	ADJ
bptjm-29	267	19	cells	cell	NOUN
bptjm-29	267	20	,	,	PUNCT
bptjm-29	267	21	which	which	PRON
bptjm-29	267	22	can	can	AUX
bptjm-29	267	23	be	be	AUX
bptjm-29	267	24	signi	signi	ADJ
bptjm-29	267	25	�	�	NOUN
bptjm-29	267	26	cant	cant	NOUN
bptjm-29	267	27	in	in	ADP
bptjm-29	267	28	pertinence	pertinence	NOUN
bptjm-29	267	29	to	to	ADP
bptjm-29	267	30	their	their	PRON
bptjm-29	267	31	utilization	utilization	NOUN
bptjm-29	267	32	as	as	ADP
bptjm-29	267	33	a	a	DET
bptjm-29	267	34	treatment	treatment	NOUN
bptjm-29	267	35	for	for	ADP
bptjm-29	267	36	als	al	NOUN
bptjm-29	267	37	and	and	CCONJ
bptjm-29	267	38	similar	similar	ADJ
bptjm-29	267	39	neurodegenerative	neurodegenerative	ADJ
bptjm-29	267	40	diseases	disease	NOUN
bptjm-29	267	41	as	as	SCONJ
bptjm-29	267	42	this	this	PRON
bptjm-29	267	43	indicates	indicate	VERB
bptjm-29	267	44	their	their	PRON
bptjm-29	267	45	ability	ability	NOUN
bptjm-29	267	46	to	to	PART
bptjm-29	267	47	e	e	VERB
bptjm-29	267	48	�	�	X
bptjm-29	267	49	ectively	ectively	ADV
bptjm-29	267	50	function	function	NOUN
bptjm-29	267	51	as	as	ADP
bptjm-29	267	52	motor	motor	NOUN
bptjm-29	267	53	or	or	CCONJ
bptjm-29	267	54	dopaminergic	dopaminergic	ADJ
bptjm-29	267	55	neurons	neuron	NOUN
bptjm-29	267	56	.	.	PUNCT
bptjm-29	268	1	this	this	DET
bptjm-29	268	2	in	in	ADP
bptjm-29	268	3	-	-	PUNCT
bptjm-29	268	4	vitro	vitro	X
bptjm-29	268	5	di	di	PROPN
bptjm-29	268	6	�	�	PROPN
bptjm-29	268	7	erentiation	erentiation	NOUN
bptjm-29	268	8	potential	potential	NOUN
bptjm-29	268	9	of	of	ADP
bptjm-29	268	10	mscs	msc	NOUN
bptjm-29	268	11	to	to	PART
bptjm-29	268	12	generate	generate	VERB
bptjm-29	268	13	a	a	DET
bptjm-29	268	14	myriad	myriad	NOUN
bptjm-29	268	15	of	of	ADP
bptjm-29	268	16	cell	cell	NOUN
bptjm-29	268	17	types	type	NOUN
bptjm-29	268	18	that	that	PRON
bptjm-29	268	19	could	could	AUX
bptjm-29	268	20	replace	replace	VERB
bptjm-29	268	21	lost	lose	VERB
bptjm-29	268	22	cells	cell	NOUN
bptjm-29	268	23	within	within	ADP
bptjm-29	268	24	injured	injured	ADJ
bptjm-29	268	25	tissue	tissue	NOUN
bptjm-29	268	26	has	have	AUX
bptjm-29	268	27	been	be	AUX
bptjm-29	268	28	a	a	DET
bptjm-29	268	29	signi	signi	ADJ
bptjm-29	268	30	�	�	NOUN
bptjm-29	268	31	cant	cant	VERB
bptjm-29	268	32	justi	justi	PROPN
bptjm-29	268	33	�	�	PROPN
bptjm-29	268	34	cation	cation	NOUN
bptjm-29	268	35	for	for	ADP
bptjm-29	268	36	the	the	DET
bptjm-29	268	37	use	use	NOUN
bptjm-29	268	38	of	of	ADP
bptjm-29	268	39	mscs	msc	NOUN
bptjm-29	268	40	themselves59	themselves59	NOUN
bptjm-29	268	41	.	.	PUNCT
bptjm-29	269	1	mscs	msc	NOUN
bptjm-29	269	2	possess	possess	VERB
bptjm-29	269	3	several	several	ADJ
bptjm-29	269	4	advantages	advantage	NOUN
bptjm-29	269	5	which	which	PRON
bptjm-29	269	6	increase	increase	VERB
bptjm-29	269	7	their	their	PRON
bptjm-29	269	8	potential	potential	NOUN
bptjm-29	269	9	of	of	ADP
bptjm-29	269	10	being	be	AUX
bptjm-29	269	11	implemented	implement	VERB
bptjm-29	269	12	in	in	ADP
bptjm-29	269	13	disease	disease	NOUN
bptjm-29	269	14	therapeutics	therapeutic	NOUN
bptjm-29	269	15	,	,	PUNCT
bptjm-29	269	16	such	such	ADJ
bptjm-29	269	17	as	as	ADP
bptjm-29	269	18	an	an	DET
bptjm-29	269	19	ability	ability	NOUN
bptjm-29	269	20	of	of	ADP
bptjm-29	269	21	self	self	NOUN
bptjm-29	269	22	-	-	PUNCT
bptjm-29	269	23	renewal	renewal	NOUN
bptjm-29	269	24	(	(	PUNCT
bptjm-29	269	25	the	the	DET
bptjm-29	269	26	process	process	NOUN
bptjm-29	269	27	by	by	ADP
bptjm-29	269	28	which	which	PRON
bptjm-29	269	29	stem	stem	NOUN
bptjm-29	269	30	cells	cell	NOUN
bptjm-29	269	31	continually	continually	ADV
bptjm-29	269	32	divide	divide	VERB
bptjm-29	269	33	to	to	PART
bptjm-29	269	34	produce	produce	VERB
bptjm-29	269	35	additional	additional	ADJ
bptjm-29	269	36	undi	undi	ADJ
bptjm-29	269	37	�	�	PROPN
bptjm-29	269	38	erentiated	erentiate	VERB
bptjm-29	269	39	stem	stem	NOUN
bptjm-29	269	40	cells	cell	NOUN
bptjm-29	269	41	)	)	PUNCT
bptjm-29	269	42	,	,	PUNCT
bptjm-29	269	43	their	their	PRON
bptjm-29	269	44	ease	ease	NOUN
bptjm-29	269	45	of	of	ADP
bptjm-29	269	46	isolation	isolation	NOUN
bptjm-29	269	47	,	,	PUNCT
bptjm-29	269	48	and	and	CCONJ
bptjm-29	269	49	a	a	DET
bptjm-29	269	50	decreased	decrease	VERB
bptjm-29	269	51	susceptibility	susceptibility	NOUN
bptjm-29	269	52	to	to	ADP
bptjm-29	269	53	tumorigenesis	tumorigenesis	NOUN
bptjm-29	269	54	(	(	PUNCT
bptjm-29	269	55	formation	formation	NOUN
bptjm-29	269	56	and	and	CCONJ
bptjm-29	269	57	accumulation	accumulation	NOUN
bptjm-29	269	58	of	of	ADP
bptjm-29	269	59	malignancy	malignancy	NOUN
bptjm-29	269	60	and	and	CCONJ
bptjm-29	269	61	malignant	malignant	ADJ
bptjm-29	269	62	properties	property	NOUN
bptjm-29	269	63	within	within	ADP
bptjm-29	269	64	cells	cell	NOUN
bptjm-29	269	65	)	)	PUNCT
bptjm-29	269	66	.	.	PUNCT
bptjm-29	270	1	in	in	ADP
bptjm-29	270	2	addition	addition	NOUN
bptjm-29	270	3	,	,	PUNCT
bptjm-29	270	4	there	there	PRON
bptjm-29	270	5	is	be	VERB
bptjm-29	270	6	no	no	DET
bptjm-29	270	7	speci	speci	NOUN
bptjm-29	270	8	�	�	PROPN
bptjm-29	270	9	c	c	PROPN
bptjm-29	270	10	immunosuppressive	immunosuppressive	ADJ
bptjm-29	270	11	treatment	treatment	NOUN
bptjm-29	270	12	that	that	PRON
bptjm-29	270	13	is	be	AUX
bptjm-29	270	14	necessary	necessary	ADJ
bptjm-29	270	15	or	or	CCONJ
bptjm-29	270	16	otherwise	otherwise	ADV
bptjm-29	270	17	warranted	warrant	VERB
bptjm-29	270	18	upon	upon	SCONJ
bptjm-29	270	19	the	the	DET
bptjm-29	270	20	transplantation	transplantation	NOUN
bptjm-29	270	21	of	of	ADP
bptjm-29	270	22	mscs	msc	NOUN
bptjm-29	270	23	,	,	PUNCT
bptjm-29	270	24	as	as	SCONJ
bptjm-29	270	25	demonstrated	demonstrate	VERB
bptjm-29	270	26	by	by	ADP
bptjm-29	270	27	the	the	DET
bptjm-29	270	28	fact	fact	NOUN
bptjm-29	270	29	that	that	SCONJ
bptjm-29	270	30	studies	study	NOUN
bptjm-29	270	31	have	have	AUX
bptjm-29	270	32	indicated	indicate	VERB
bptjm-29	270	33	that	that	SCONJ
bptjm-29	270	34	mscs	msc	NOUN
bptjm-29	270	35	are	be	AUX
bptjm-29	270	36	immunosuppressive	immunosuppressive	ADJ
bptjm-29	270	37	both	both	CCONJ
bptjm-29	270	38	in	in	ADP
bptjm-29	270	39	vivo	vivo	NOUN
bptjm-29	270	40	and	and	CCONJ
bptjm-29	270	41	in	in	ADP
bptjm-29	270	42	vitro9,60	vitro9,60	NOUN
bptjm-29	270	43	.	.	PUNCT
bptjm-29	271	1	typically	typically	ADV
bptjm-29	271	2	,	,	PUNCT
bptjm-29	271	3	mscs	msc	NOUN
bptjm-29	271	4	employ	employ	VERB
bptjm-29	271	5	this	this	DET
bptjm-29	271	6	immunosuppressive	immunosuppressive	ADJ
bptjm-29	271	7	e	e	NOUN
bptjm-29	271	8	�	�	NOUN
bptjm-29	271	9	ect	ect	VERB
bptjm-29	271	10	on	on	ADP
bptjm-29	271	11	t	t	NOUN
bptjm-29	271	12	cells	cell	NOUN
bptjm-29	271	13	,	,	PUNCT
bptjm-29	271	14	which	which	PRON
bptjm-29	271	15	are	be	AUX
bptjm-29	271	16	a	a	DET
bptjm-29	271	17	major	major	ADJ
bptjm-29	271	18	component	component	NOUN
bptjm-29	271	19	of	of	ADP
bptjm-29	271	20	the	the	DET
bptjm-29	271	21	adaptive	adaptive	ADJ
bptjm-29	271	22	immune	immune	ADJ
bptjm-29	271	23	system	system	NOUN
bptjm-29	271	24	.	.	PUNCT
bptjm-29	272	1	most	most	ADJ
bptjm-29	272	2	signi	signi	ADJ
bptjm-29	272	3	�	�	NOUN
bptjm-29	272	4	cantly	cantly	ADV
bptjm-29	272	5	,	,	PUNCT
bptjm-29	272	6	however	however	ADV
bptjm-29	272	7	,	,	PUNCT
bptjm-29	272	8	the	the	DET
bptjm-29	272	9	therapeutic	therapeutic	ADJ
bptjm-29	272	10	e	e	NOUN
bptjm-29	272	11	�	�	NOUN
bptjm-29	272	12	ects	ect	NOUN
bptjm-29	272	13	of	of	ADP
bptjm-29	272	14	mscs	msc	NOUN
bptjm-29	272	15	are	be	AUX
bptjm-29	272	16	largely	largely	ADV
bptjm-29	272	17	associated	associate	VERB
bptjm-29	272	18	with	with	ADP
bptjm-29	272	19	their	their	PRON
bptjm-29	272	20	immunomodulatory	immunomodulatory	ADJ
bptjm-29	272	21	e	e	NOUN
bptjm-29	272	22	�	�	NOUN
bptjm-29	272	23	ects	ect	NOUN
bptjm-29	272	24	,	,	PUNCT
bptjm-29	272	25	which	which	PRON
bptjm-29	272	26	include	include	VERB
bptjm-29	272	27	mscs	msc	NOUN
bptjm-29	272	28	’	'	PUNCT
bptjm-29	272	29	regulation	regulation	NOUN
bptjm-29	272	30	of	of	ADP
bptjm-29	272	31	lymphocytes	lymphocyte	NOUN
bptjm-29	272	32	that	that	PRON
bptjm-29	272	33	are	be	AUX
bptjm-29	272	34	associated	associate	VERB
bptjm-29	272	35	with	with	ADP
bptjm-29	272	36	the	the	DET
bptjm-29	272	37	innate	innate	ADJ
bptjm-29	272	38	and	and	CCONJ
bptjm-29	272	39	adaptive	adaptive	ADJ
bptjm-29	272	40	immune	immune	ADJ
bptjm-29	272	41	system8	system8	PROPN
bptjm-29	272	42	.	.	PUNCT
bptjm-29	273	1	immunomodulation	immunomodulation	NOUN
bptjm-29	273	2	is	be	AUX
bptjm-29	273	3	the	the	DET
bptjm-29	273	4	modulation	modulation	NOUN
bptjm-29	273	5	or	or	CCONJ
bptjm-29	273	6	alteration	alteration	NOUN
bptjm-29	273	7	of	of	ADP
bptjm-29	273	8	the	the	DET
bptjm-29	273	9	immune	immune	ADJ
bptjm-29	273	10	system	system	NOUN
bptjm-29	273	11	,	,	PUNCT
bptjm-29	273	12	as	as	SCONJ
bptjm-29	273	13	determined	determine	VERB
bptjm-29	273	14	by	by	ADP
bptjm-29	273	15	the	the	DET
bptjm-29	273	16	activation	activation	NOUN
bptjm-29	273	17	or	or	CCONJ
bptjm-29	273	18	suppression	suppression	NOUN
bptjm-29	273	19	of	of	ADP
bptjm-29	273	20	immunomodulating	immunomodulate	VERB
bptjm-29	273	21	berkeley	berkeley	PROPN
bptjm-29	273	22	pharma	pharma	PROPN
bptjm-29	273	23	tech	tech	NOUN
bptjm-29	273	24	journal	journal	NOUN
bptjm-29	273	25	of	of	ADP
bptjm-29	273	26	medicine	medicine	NOUN
bptjm-29	273	27	|	|	ADV
bptjm-29	273	28	89	89	NUM
bptjm-29	274	1	https://www.zotero.org/google-docs/?r2qmvd	https://www.zotero.org/google-docs/?r2qmvd	PROPN
bptjm-29	274	2	https://www.zotero.org/google-docs/?udimnl	https://www.zotero.org/google-docs/?udimnl	PROPN
bptjm-29	274	3	https://www.zotero.org/google-docs/?znilkj	https://www.zotero.org/google-docs/?znilkj	PROPN
bptjm-29	274	4	https://www.zotero.org/google-docs/?fga3bi	https://www.zotero.org/google-docs/?fga3bi	PROPN
bptjm-29	275	1	https://www.zotero.org/google-docs/?yxjjze	https://www.zotero.org/google-docs/?yxjjze	PROPN
bptjm-29	275	2	agents	agent	NOUN
bptjm-29	275	3	such	such	ADJ
bptjm-29	275	4	as	as	ADP
bptjm-29	275	5	cytokines	cytokine	NOUN
bptjm-29	275	6	,	,	PUNCT
bptjm-29	275	7	vaccines	vaccine	NOUN
bptjm-29	275	8	,	,	PUNCT
bptjm-29	275	9	and	and	CCONJ
bptjm-29	275	10	monoclonal	monoclonal	NOUN
bptjm-29	275	11	antibodies	antibodie	VERB
bptjm-29	275	12	.	.	PUNCT
bptjm-29	276	1	speci	speci	PROPN
bptjm-29	276	2	�	�	PROPN
bptjm-29	276	3	cally	cally	ADV
bptjm-29	276	4	,	,	PUNCT
bptjm-29	276	5	mscs	msc	NOUN
bptjm-29	276	6	are	be	AUX
bptjm-29	276	7	able	able	ADJ
bptjm-29	276	8	to	to	PART
bptjm-29	276	9	regulate	regulate	VERB
bptjm-29	276	10	t	t	PROPN
bptjm-29	276	11	cell	cell	NOUN
bptjm-29	276	12	proliferation	proliferation	NOUN
bptjm-29	276	13	and	and	CCONJ
bptjm-29	276	14	have	have	VERB
bptjm-29	276	15	the	the	DET
bptjm-29	276	16	potency	potency	NOUN
bptjm-29	276	17	to	to	PART
bptjm-29	276	18	upregulate	upregulate	VERB
bptjm-29	276	19	regulatory	regulatory	ADJ
bptjm-29	276	20	t	t	NOUN
bptjm-29	276	21	cell	cell	NOUN
bptjm-29	276	22	function	function	NOUN
bptjm-29	276	23	,	,	PUNCT
bptjm-29	276	24	thus	thus	ADV
bptjm-29	276	25	simultaneously	simultaneously	ADV
bptjm-29	276	26	highlighting	highlight	VERB
bptjm-29	276	27	their	their	PRON
bptjm-29	276	28	immunosuppressive	immunosuppressive	ADJ
bptjm-29	276	29	abilities	ability	NOUN
bptjm-29	276	30	because	because	SCONJ
bptjm-29	276	31	the	the	DET
bptjm-29	276	32	regulatory	regulatory	ADJ
bptjm-29	276	33	t	t	NOUN
bptjm-29	276	34	cells	cell	NOUN
bptjm-29	276	35	function	function	VERB
bptjm-29	276	36	to	to	PART
bptjm-29	276	37	suppress	suppress	VERB
bptjm-29	276	38	the	the	DET
bptjm-29	276	39	body	body	NOUN
bptjm-29	276	40	’s	’s	PART
bptjm-29	276	41	immune	immune	ADJ
bptjm-29	276	42	response	response	NOUN
bptjm-29	276	43	,	,	PUNCT
bptjm-29	276	44	allowing	allow	VERB
bptjm-29	276	45	for	for	ADP
bptjm-29	276	46	a	a	DET
bptjm-29	276	47	maintenance	maintenance	NOUN
bptjm-29	276	48	of	of	ADP
bptjm-29	276	49	homeostasis	homeostasis	NOUN
bptjm-29	276	50	.	.	PUNCT
bptjm-29	277	1	for	for	ADP
bptjm-29	277	2	this	this	DET
bptjm-29	277	3	reason	reason	NOUN
bptjm-29	277	4	,	,	PUNCT
bptjm-29	277	5	there	there	PRON
bptjm-29	277	6	have	have	AUX
bptjm-29	277	7	been	be	AUX
bptjm-29	277	8	proposals	proposal	NOUN
bptjm-29	277	9	for	for	ADP
bptjm-29	277	10	the	the	DET
bptjm-29	277	11	application	application	NOUN
bptjm-29	277	12	of	of	ADP
bptjm-29	277	13	mscs	msc	NOUN
bptjm-29	277	14	to	to	ADP
bptjm-29	277	15	the	the	DET
bptjm-29	277	16	treatment	treatment	NOUN
bptjm-29	277	17	of	of	ADP
bptjm-29	277	18	autoimmune	autoimmune	ADJ
bptjm-29	277	19	diseases	disease	NOUN
bptjm-29	277	20	,	,	PUNCT
bptjm-29	277	21	which	which	PRON
bptjm-29	277	22	are	be	AUX
bptjm-29	277	23	a	a	DET
bptjm-29	277	24	category	category	NOUN
bptjm-29	277	25	of	of	ADP
bptjm-29	277	26	diseases	disease	NOUN
bptjm-29	277	27	in	in	ADP
bptjm-29	277	28	which	which	PRON
bptjm-29	277	29	healthy	healthy	ADJ
bptjm-29	277	30	cells	cell	NOUN
bptjm-29	277	31	are	be	AUX
bptjm-29	277	32	attacked	attack	VERB
bptjm-29	277	33	by	by	ADP
bptjm-29	277	34	the	the	DET
bptjm-29	277	35	body	body	NOUN
bptjm-29	277	36	’s	’s	PART
bptjm-29	277	37	immune	immune	ADJ
bptjm-29	277	38	system	system	NOUN
bptjm-29	277	39	.	.	PUNCT
bptjm-29	278	1	mscs	msc	NOUN
bptjm-29	278	2	also	also	ADV
bptjm-29	278	3	regulate	regulate	VERB
bptjm-29	278	4	their	their	PRON
bptjm-29	278	5	immunomodulatory	immunomodulatory	ADJ
bptjm-29	278	6	function	function	NOUN
bptjm-29	278	7	in	in	ADP
bptjm-29	278	8	accordance	accordance	NOUN
bptjm-29	278	9	with	with	ADP
bptjm-29	278	10	micro	micro	PROPN
bptjm-29	278	11	environmental	environmental	ADJ
bptjm-29	278	12	and	and	CCONJ
bptjm-29	278	13	in	in	ADP
bptjm-29	278	14	�	�	NOUN
bptjm-29	278	15	ammatory	ammatory	NOUN
bptjm-29	278	16	conditions	condition	NOUN
bptjm-29	278	17	,	,	PUNCT
bptjm-29	278	18	indicative	indicative	ADJ
bptjm-29	278	19	of	of	ADP
bptjm-29	278	20	the	the	DET
bptjm-29	278	21	high	high	ADJ
bptjm-29	278	22	level	level	NOUN
bptjm-29	278	23	of	of	ADP
bptjm-29	278	24	therapeutic	therapeutic	ADJ
bptjm-29	278	25	plasticity	plasticity	NOUN
bptjm-29	278	26	of	of	ADP
bptjm-29	278	27	mscs	msc	NOUN
bptjm-29	278	28	(	(	PUNCT
bptjm-29	278	29	they	they	PRON
bptjm-29	278	30	have	have	AUX
bptjm-29	278	31	a	a	DET
bptjm-29	278	32	potential	potential	NOUN
bptjm-29	278	33	of	of	ADP
bptjm-29	278	34	being	be	AUX
bptjm-29	278	35	applied	apply	VERB
bptjm-29	278	36	in	in	ADP
bptjm-29	278	37	order	order	NOUN
bptjm-29	278	38	to	to	PART
bptjm-29	278	39	treat	treat	VERB
bptjm-29	278	40	a	a	DET
bptjm-29	278	41	myriad	myriad	NOUN
bptjm-29	278	42	of	of	ADP
bptjm-29	278	43	medical	medical	ADJ
bptjm-29	278	44	conditions	condition	NOUN
bptjm-29	278	45	)	)	PUNCT
bptjm-29	278	46	.	.	PUNCT
bptjm-29	279	1	mscs	msc	NOUN
bptjm-29	279	2	function	function	VERB
bptjm-29	279	3	upon	upon	SCONJ
bptjm-29	279	4	transplantation	transplantation	NOUN
bptjm-29	279	5	through	through	ADP
bptjm-29	279	6	various	various	ADJ
bptjm-29	279	7	methods	method	NOUN
bptjm-29	279	8	.	.	PUNCT
bptjm-29	280	1	one	one	NUM
bptjm-29	280	2	such	such	ADJ
bptjm-29	280	3	method	method	NOUN
bptjm-29	280	4	is	be	AUX
bptjm-29	280	5	cell	cell	NOUN
bptjm-29	280	6	fusion	fusion	NOUN
bptjm-29	280	7	,	,	PUNCT
bptjm-29	280	8	which	which	PRON
bptjm-29	280	9	is	be	AUX
bptjm-29	280	10	the	the	DET
bptjm-29	280	11	process	process	NOUN
bptjm-29	280	12	of	of	ADP
bptjm-29	280	13	a	a	DET
bptjm-29	280	14	cell	cell	NOUN
bptjm-29	280	15	interacting	interact	VERB
bptjm-29	280	16	with	with	ADP
bptjm-29	280	17	nearby	nearby	ADJ
bptjm-29	280	18	cells	cell	NOUN
bptjm-29	280	19	in	in	ADP
bptjm-29	280	20	order	order	NOUN
bptjm-29	280	21	to	to	PART
bptjm-29	280	22	form	form	VERB
bptjm-29	280	23	a	a	DET
bptjm-29	280	24	multicellular	multicellular	ADJ
bptjm-29	280	25	assemblage	assemblage	NOUN
bptjm-29	280	26	with	with	ADP
bptjm-29	280	27	a	a	DET
bptjm-29	280	28	universal	universal	ADJ
bptjm-29	280	29	function	function	NOUN
bptjm-29	280	30	.	.	PUNCT
bptjm-29	281	1	for	for	ADP
bptjm-29	281	2	instance	instance	NOUN
bptjm-29	281	3	,	,	PUNCT
bptjm-29	281	4	the	the	DET
bptjm-29	281	5	fusion	fusion	NOUN
bptjm-29	281	6	of	of	ADP
bptjm-29	281	7	mscs	msc	NOUN
bptjm-29	281	8	with	with	ADP
bptjm-29	281	9	rodent	rodent	ADJ
bptjm-29	281	10	purkinje	purkinje	PROPN
bptjm-29	281	11	cells	cell	NOUN
bptjm-29	281	12	was	be	AUX
bptjm-29	281	13	observed	observe	VERB
bptjm-29	281	14	,	,	PUNCT
bptjm-29	281	15	and	and	CCONJ
bptjm-29	281	16	these	these	DET
bptjm-29	281	17	fused	fuse	VERB
bptjm-29	281	18	cells	cell	NOUN
bptjm-29	281	19	were	be	AUX
bptjm-29	281	20	implemented	implement	VERB
bptjm-29	281	21	to	to	PART
bptjm-29	281	22	improve	improve	VERB
bptjm-29	281	23	the	the	DET
bptjm-29	281	24	therapy	therapy	NOUN
bptjm-29	281	25	of	of	ADP
bptjm-29	281	26	neurodegenerative	neurodegenerative	ADJ
bptjm-29	281	27	disorders	disorder	NOUN
bptjm-29	281	28	and	and	CCONJ
bptjm-29	281	29	disorders	disorder	NOUN
bptjm-29	281	30	involving	involve	VERB
bptjm-29	281	31	the	the	DET
bptjm-29	281	32	cerebellum56	cerebellum56	NOUN
bptjm-29	281	33	.	.	PUNCT
bptjm-29	282	1	furthermore	furthermore	ADV
bptjm-29	282	2	,	,	PUNCT
bptjm-29	282	3	mitochondrial	mitochondrial	ADJ
bptjm-29	282	4	transfer	transfer	NOUN
bptjm-29	282	5	is	be	AUX
bptjm-29	282	6	a	a	DET
bptjm-29	282	7	unique	unique	ADJ
bptjm-29	282	8	mechanism	mechanism	NOUN
bptjm-29	282	9	of	of	ADP
bptjm-29	282	10	action	action	NOUN
bptjm-29	282	11	of	of	ADP
bptjm-29	282	12	mscs	msc	NOUN
bptjm-29	282	13	,	,	PUNCT
bptjm-29	282	14	and	and	CCONJ
bptjm-29	282	15	is	be	AUX
bptjm-29	282	16	the	the	DET
bptjm-29	282	17	process	process	NOUN
bptjm-29	282	18	in	in	ADP
bptjm-29	282	19	which	which	PRON
bptjm-29	282	20	cells	cell	NOUN
bptjm-29	282	21	transfer	transfer	VERB
bptjm-29	282	22	mitochondria	mitochondria	NOUN
bptjm-29	282	23	to	to	ADP
bptjm-29	282	24	neighboring	neighbor	VERB
bptjm-29	282	25	injured	injure	VERB
bptjm-29	282	26	cells	cell	NOUN
bptjm-29	282	27	(	(	PUNCT
bptjm-29	282	28	thus	thus	ADV
bptjm-29	282	29	replacing	replace	VERB
bptjm-29	282	30	damaged	damage	VERB
bptjm-29	282	31	mitochondria	mitochondria	NOUN
bptjm-29	282	32	and	and	CCONJ
bptjm-29	282	33	aiding	aid	VERB
bptjm-29	282	34	in	in	ADP
bptjm-29	282	35	the	the	DET
bptjm-29	282	36	restoration	restoration	NOUN
bptjm-29	282	37	of	of	ADP
bptjm-29	282	38	cellular	cellular	ADJ
bptjm-29	282	39	function	function	NOUN
bptjm-29	282	40	)	)	PUNCT
bptjm-29	282	41	.	.	PUNCT
bptjm-29	283	1	additionally	additionally	ADV
bptjm-29	283	2	,	,	PUNCT
bptjm-29	283	3	the	the	DET
bptjm-29	283	4	secretion	secretion	NOUN
bptjm-29	283	5	of	of	ADP
bptjm-29	283	6	extracellular	extracellular	ADJ
bptjm-29	283	7	vesicles	vesicle	NOUN
bptjm-29	283	8	(	(	PUNCT
bptjm-29	283	9	exosomes	exosome	NOUN
bptjm-29	283	10	)	)	PUNCT
bptjm-29	283	11	by	by	ADP
bptjm-29	283	12	mscs	msc	NOUN
bptjm-29	283	13	is	be	AUX
bptjm-29	283	14	a	a	DET
bptjm-29	283	15	similarly	similarly	ADV
bptjm-29	283	16	important	important	ADJ
bptjm-29	283	17	mechanism	mechanism	NOUN
bptjm-29	283	18	of	of	ADP
bptjm-29	283	19	action	action	NOUN
bptjm-29	283	20	.	.	PUNCT
bptjm-29	284	1	msc	msc	PROPN
bptjm-29	284	2	exosomes	exosome	NOUN
bptjm-29	284	3	are	be	AUX
bptjm-29	284	4	secreted	secrete	VERB
bptjm-29	284	5	into	into	ADP
bptjm-29	284	6	the	the	DET
bptjm-29	284	7	extracellular	extracellular	ADJ
bptjm-29	284	8	space	space	NOUN
bptjm-29	284	9	with	with	ADP
bptjm-29	284	10	multivesicular	multivesicular	ADJ
bptjm-29	284	11	bodies	body	NOUN
bptjm-29	284	12	within	within	ADP
bptjm-29	284	13	mscs	msc	NOUN
bptjm-29	284	14	fused	fuse	VERB
bptjm-29	284	15	with	with	ADP
bptjm-29	284	16	the	the	DET
bptjm-29	284	17	cellular	cellular	ADJ
bptjm-29	284	18	membrane59	membrane59	NOUN
bptjm-29	284	19	.	.	PUNCT
bptjm-29	285	1	extracellular	extracellular	ADJ
bptjm-29	285	2	vesicles	vesicle	NOUN
bptjm-29	285	3	have	have	VERB
bptjm-29	285	4	the	the	DET
bptjm-29	285	5	potency	potency	NOUN
bptjm-29	285	6	to	to	PART
bptjm-29	285	7	transport	transport	VERB
bptjm-29	285	8	essential	essential	ADJ
bptjm-29	285	9	macromolecules	macromolecule	NOUN
bptjm-29	285	10	such	such	ADJ
bptjm-29	285	11	as	as	ADP
bptjm-29	285	12	genetic	genetic	ADJ
bptjm-29	285	13	material	material	NOUN
bptjm-29	285	14	to	to	ADP
bptjm-29	285	15	neighboring	neighboring	NOUN
bptjm-29	285	16	cells	cell	NOUN
bptjm-29	285	17	through	through	ADP
bptjm-29	285	18	endocytosis	endocytosis	NOUN
bptjm-29	285	19	to	to	PART
bptjm-29	285	20	maintain	maintain	VERB
bptjm-29	285	21	physiological	physiological	ADJ
bptjm-29	285	22	homeostasis	homeostasis	NOUN
bptjm-29	285	23	,	,	PUNCT
bptjm-29	285	24	and	and	CCONJ
bptjm-29	285	25	as	as	ADP
bptjm-29	285	26	such	such	ADJ
bptjm-29	285	27	,	,	PUNCT
bptjm-29	285	28	carry	carry	VERB
bptjm-29	285	29	a	a	DET
bptjm-29	285	30	potential	potential	ADJ
bptjm-29	285	31	therapeutic	therapeutic	ADJ
bptjm-29	285	32	application	application	NOUN
bptjm-29	285	33	.	.	PUNCT
bptjm-29	286	1	studies	study	NOUN
bptjm-29	286	2	have	have	AUX
bptjm-29	286	3	demonstrated	demonstrate	VERB
bptjm-29	286	4	that	that	SCONJ
bptjm-29	286	5	the	the	DET
bptjm-29	286	6	exosomes	exosome	NOUN
bptjm-29	286	7	secreted	secrete	VERB
bptjm-29	286	8	by	by	ADP
bptjm-29	286	9	mscs	msc	NOUN
bptjm-29	286	10	possess	possess	VERB
bptjm-29	286	11	anti	anti	ADJ
bptjm-29	286	12	-	-	ADJ
bptjm-29	286	13	in	in	ADP
bptjm-29	286	14	�	�	NOUN
bptjm-29	286	15	ammatory	ammatory	NOUN
bptjm-29	286	16	and	and	CCONJ
bptjm-29	286	17	regenerative	regenerative	ADJ
bptjm-29	286	18	properties	property	NOUN
bptjm-29	286	19	in	in	ADP
bptjm-29	286	20	pertinence	pertinence	NOUN
bptjm-29	286	21	to	to	ADP
bptjm-29	286	22	traumatic	traumatic	ADJ
bptjm-29	286	23	brain	brain	NOUN
bptjm-29	286	24	injury	injury	NOUN
bptjm-29	286	25	,	,	PUNCT
bptjm-29	286	26	stroke	stroke	NOUN
bptjm-29	286	27	,	,	PUNCT
bptjm-29	286	28	perinatal	perinatal	ADJ
bptjm-29	286	29	brain	brain	NOUN
bptjm-29	286	30	injury	injury	NOUN
bptjm-29	286	31	,	,	PUNCT
bptjm-29	286	32	and	and	CCONJ
bptjm-29	286	33	wound	wound	NOUN
bptjm-29	286	34	healing61	healing61	NOUN
bptjm-29	286	35	,	,	PUNCT
bptjm-29	286	36	highlighting	highlight	VERB
bptjm-29	286	37	that	that	SCONJ
bptjm-29	286	38	msc	msc	NOUN
bptjm-29	286	39	-	-	PUNCT
bptjm-29	286	40	derived	derive	VERB
bptjm-29	286	41	exosomes	exosome	NOUN
bptjm-29	286	42	are	be	AUX
bptjm-29	286	43	crucial	crucial	ADJ
bptjm-29	286	44	to	to	ADP
bptjm-29	286	45	the	the	DET
bptjm-29	286	46	proper	proper	ADJ
bptjm-29	286	47	function	function	NOUN
bptjm-29	286	48	and	and	CCONJ
bptjm-29	286	49	therapeutic	therapeutic	ADJ
bptjm-29	286	50	properties	property	NOUN
bptjm-29	286	51	of	of	ADP
bptjm-29	286	52	mscs	msc	NOUN
bptjm-29	286	53	as	as	ADP
bptjm-29	286	54	a	a	DET
bptjm-29	286	55	whole	whole	NOUN
bptjm-29	286	56	.	.	PUNCT
bptjm-29	287	1	berkeley	berkeley	PROPN
bptjm-29	287	2	pharma	pharma	PROPN
bptjm-29	287	3	tech	tech	PROPN
bptjm-29	287	4	journal	journal	NOUN
bptjm-29	287	5	of	of	ADP
bptjm-29	287	6	medicine	medicine	NOUN
bptjm-29	287	7	|	|	ADV
bptjm-29	287	8	90	90	NUM
bptjm-29	287	9	https://www.zotero.org/google-docs/?vgfg1q	https://www.zotero.org/google-docs/?vgfg1q	NOUN
bptjm-29	287	10	https://www.zotero.org/google-docs/?pqc90s	https://www.zotero.org/google-docs/?pqc90s	PRON
bptjm-29	287	11	https://www.zotero.org/google-docs/?wi3wxm	https://www.zotero.org/google-docs/?wi3wxm	VERB
bptjm-29	287	12	there	there	PRON
bptjm-29	287	13	are	be	VERB
bptjm-29	287	14	certain	certain	ADJ
bptjm-29	287	15	characteristics	characteristic	NOUN
bptjm-29	287	16	of	of	ADP
bptjm-29	287	17	mscs	msc	NOUN
bptjm-29	287	18	that	that	PRON
bptjm-29	287	19	aid	aid	VERB
bptjm-29	287	20	in	in	ADP
bptjm-29	287	21	their	their	PRON
bptjm-29	287	22	applications	application	NOUN
bptjm-29	287	23	within	within	ADP
bptjm-29	287	24	regenerative	regenerative	ADJ
bptjm-29	287	25	medicine56	medicine56	NOUN
bptjm-29	287	26	.	.	PUNCT
bptjm-29	288	1	mscs	msc	NOUN
bptjm-29	288	2	have	have	VERB
bptjm-29	288	3	the	the	DET
bptjm-29	288	4	ability	ability	NOUN
bptjm-29	288	5	to	to	PART
bptjm-29	288	6	form	form	VERB
bptjm-29	288	7	colonies	colony	NOUN
bptjm-29	288	8	,	,	PUNCT
bptjm-29	288	9	which	which	PRON
bptjm-29	288	10	can	can	AUX
bptjm-29	288	11	be	be	AUX
bptjm-29	288	12	measured	measure	VERB
bptjm-29	288	13	by	by	ADP
bptjm-29	288	14	the	the	DET
bptjm-29	288	15	term	term	NOUN
bptjm-29	288	16	“	"	PUNCT
bptjm-29	288	17	colony	colony	NOUN
bptjm-29	288	18	forming	form	VERB
bptjm-29	288	19	unit	unit	NOUN
bptjm-29	288	20	”	"	PUNCT
bptjm-29	288	21	(	(	PUNCT
bptjm-29	288	22	cfu	cfu	NOUN
bptjm-29	288	23	)	)	PUNCT
bptjm-29	288	24	.	.	PUNCT
bptjm-29	289	1	a	a	DET
bptjm-29	289	2	cfu	cfu	NOUN
bptjm-29	289	3	is	be	AUX
bptjm-29	289	4	a	a	DET
bptjm-29	289	5	measure	measure	NOUN
bptjm-29	289	6	of	of	ADP
bptjm-29	289	7	the	the	DET
bptjm-29	289	8	number	number	NOUN
bptjm-29	289	9	of	of	ADP
bptjm-29	289	10	viable	viable	ADJ
bptjm-29	289	11	cells	cell	NOUN
bptjm-29	289	12	within	within	ADP
bptjm-29	289	13	a	a	DET
bptjm-29	289	14	sample	sample	NOUN
bptjm-29	289	15	that	that	PRON
bptjm-29	289	16	are	be	AUX
bptjm-29	289	17	able	able	ADJ
bptjm-29	289	18	to	to	PART
bptjm-29	289	19	multiply	multiply	VERB
bptjm-29	289	20	through	through	ADP
bptjm-29	289	21	binary	binary	PROPN
bptjm-29	289	22	�	�	PROPN
bptjm-29	289	23	ssion	ssion	NOUN
bptjm-29	289	24	.	.	PUNCT
bptjm-29	290	1	this	this	PRON
bptjm-29	290	2	is	be	AUX
bptjm-29	290	3	one	one	NUM
bptjm-29	290	4	of	of	ADP
bptjm-29	290	5	the	the	DET
bptjm-29	290	6	primary	primary	ADJ
bptjm-29	290	7	functional	functional	ADJ
bptjm-29	290	8	characteristics	characteristic	NOUN
bptjm-29	290	9	of	of	ADP
bptjm-29	290	10	mscs	msc	NOUN
bptjm-29	290	11	,	,	PUNCT
bptjm-29	290	12	which	which	PRON
bptjm-29	290	13	highlights	highlight	VERB
bptjm-29	290	14	their	their	PRON
bptjm-29	290	15	ability	ability	NOUN
bptjm-29	290	16	to	to	PART
bptjm-29	290	17	proliferate	proliferate	VERB
bptjm-29	290	18	upon	upon	SCONJ
bptjm-29	290	19	transplantation	transplantation	NOUN
bptjm-29	290	20	and	and	CCONJ
bptjm-29	290	21	which	which	PRON
bptjm-29	290	22	would	would	AUX
bptjm-29	290	23	reasonably	reasonably	ADV
bptjm-29	290	24	eliminate	eliminate	VERB
bptjm-29	290	25	(	(	PUNCT
bptjm-29	290	26	1	1	X
bptjm-29	290	27	)	)	PUNCT
bptjm-29	290	28	the	the	DET
bptjm-29	290	29	need	need	NOUN
bptjm-29	290	30	for	for	ADP
bptjm-29	290	31	consecutive	consecutive	ADJ
bptjm-29	290	32	transplantations	transplantation	NOUN
bptjm-29	290	33	and	and	CCONJ
bptjm-29	290	34	(	(	PUNCT
bptjm-29	290	35	2	2	X
bptjm-29	290	36	)	)	PUNCT
bptjm-29	290	37	possible	possible	ADJ
bptjm-29	290	38	supply	supply	NOUN
bptjm-29	290	39	shortages	shortage	NOUN
bptjm-29	290	40	associated	associate	VERB
bptjm-29	290	41	with	with	ADP
bptjm-29	290	42	the	the	DET
bptjm-29	290	43	availability	availability	NOUN
bptjm-29	290	44	of	of	ADP
bptjm-29	290	45	mscs	msc	NOUN
bptjm-29	290	46	.	.	PUNCT
bptjm-29	291	1	in	in	ADP
bptjm-29	291	2	addition	addition	NOUN
bptjm-29	291	3	,	,	PUNCT
bptjm-29	291	4	while	while	SCONJ
bptjm-29	291	5	it	it	PRON
bptjm-29	291	6	has	have	AUX
bptjm-29	291	7	been	be	AUX
bptjm-29	291	8	discussed	discuss	VERB
bptjm-29	291	9	above	above	ADP
bptjm-29	291	10	that	that	SCONJ
bptjm-29	291	11	mscs	msc	NOUN
bptjm-29	291	12	have	have	VERB
bptjm-29	291	13	a	a	DET
bptjm-29	291	14	high	high	ADJ
bptjm-29	291	15	di	di	NOUN
bptjm-29	291	16	�	�	PROPN
bptjm-29	291	17	erentiation	erentiation	NOUN
bptjm-29	291	18	plasticity	plasticity	NOUN
bptjm-29	291	19	as	as	SCONJ
bptjm-29	291	20	compared	compare	VERB
bptjm-29	291	21	to	to	ADP
bptjm-29	291	22	other	other	ADJ
bptjm-29	291	23	stem	stem	NOUN
bptjm-29	291	24	cells	cell	NOUN
bptjm-29	291	25	,	,	PUNCT
bptjm-29	291	26	mscs	msc	NOUN
bptjm-29	291	27	have	have	VERB
bptjm-29	291	28	the	the	DET
bptjm-29	291	29	unique	unique	ADJ
bptjm-29	291	30	capability	capability	NOUN
bptjm-29	291	31	of	of	ADP
bptjm-29	291	32	undergoing	undergo	VERB
bptjm-29	291	33	trilineage	trilineage	NOUN
bptjm-29	291	34	di	di	NOUN
bptjm-29	291	35	�	�	NOUN
bptjm-29	291	36	erentiation	erentiation	NOUN
bptjm-29	291	37	into	into	ADP
bptjm-29	291	38	adipocytes	adipocyte	NOUN
bptjm-29	291	39	(	(	PUNCT
bptjm-29	291	40	fat	fat	ADJ
bptjm-29	291	41	cells	cell	NOUN
bptjm-29	291	42	which	which	PRON
bptjm-29	291	43	store	store	VERB
bptjm-29	291	44	energy	energy	NOUN
bptjm-29	291	45	as	as	ADP
bptjm-29	291	46	fat	fat	ADJ
bptjm-29	291	47	)	)	PUNCT
bptjm-29	291	48	,	,	PUNCT
bptjm-29	291	49	chondrocytes	chondrocyte	NOUN
bptjm-29	291	50	(	(	PUNCT
bptjm-29	291	51	key	key	ADJ
bptjm-29	291	52	component	component	NOUN
bptjm-29	291	53	of	of	ADP
bptjm-29	291	54	cartilage	cartilage	NOUN
bptjm-29	291	55	tissue	tissue	NOUN
bptjm-29	291	56	)	)	PUNCT
bptjm-29	291	57	,	,	PUNCT
bptjm-29	291	58	and	and	CCONJ
bptjm-29	291	59	osteocytes	osteocyte	NOUN
bptjm-29	291	60	(	(	PUNCT
bptjm-29	291	61	bone	bone	NOUN
bptjm-29	291	62	cells	cell	NOUN
bptjm-29	291	63	which	which	PRON
bptjm-29	291	64	make	make	VERB
bptjm-29	291	65	up	up	ADP
bptjm-29	291	66	approximately	approximately	ADV
bptjm-29	291	67	90	90	NUM
bptjm-29	291	68	-	-	SYM
bptjm-29	291	69	95	95	NUM
bptjm-29	291	70	%	%	NOUN
bptjm-29	291	71	of	of	ADP
bptjm-29	291	72	cells	cell	NOUN
bptjm-29	291	73	within	within	ADP
bptjm-29	291	74	bone	bone	NOUN
bptjm-29	291	75	tissue	tissue	NOUN
bptjm-29	291	76	)	)	PUNCT
bptjm-29	291	77	.	.	PUNCT
bptjm-29	292	1	furthermore	furthermore	ADV
bptjm-29	292	2	,	,	PUNCT
bptjm-29	292	3	the	the	DET
bptjm-29	292	4	telomerase	telomerase	NOUN
bptjm-29	292	5	activity	activity	NOUN
bptjm-29	292	6	of	of	ADP
bptjm-29	292	7	mscs	msc	NOUN
bptjm-29	292	8	is	be	AUX
bptjm-29	292	9	signi	signi	ADJ
bptjm-29	292	10	�	�	NOUN
bptjm-29	292	11	cant	cant	NOUN
bptjm-29	292	12	as	as	SCONJ
bptjm-29	292	13	their	their	PRON
bptjm-29	292	14	activity	activity	NOUN
bptjm-29	292	15	is	be	AUX
bptjm-29	292	16	typically	typically	ADV
bptjm-29	292	17	augmented	augment	VERB
bptjm-29	292	18	within	within	ADP
bptjm-29	292	19	mscs	msc	NOUN
bptjm-29	292	20	.	.	PUNCT
bptjm-29	293	1	telomeres	telomere	NOUN
bptjm-29	293	2	are	be	AUX
bptjm-29	293	3	the	the	DET
bptjm-29	293	4	end	end	NOUN
bptjm-29	293	5	caps	cap	NOUN
bptjm-29	293	6	of	of	ADP
bptjm-29	293	7	chromosomes	chromosome	NOUN
bptjm-29	293	8	which	which	PRON
bptjm-29	293	9	shorten	shorten	VERB
bptjm-29	293	10	with	with	ADP
bptjm-29	293	11	cell	cell	NOUN
bptjm-29	293	12	replication	replication	NOUN
bptjm-29	293	13	and	and	CCONJ
bptjm-29	293	14	division	division	NOUN
bptjm-29	293	15	,	,	PUNCT
bptjm-29	293	16	and	and	CCONJ
bptjm-29	293	17	similarly	similarly	ADV
bptjm-29	293	18	,	,	PUNCT
bptjm-29	293	19	telomerase	telomerase	NOUN
bptjm-29	293	20	is	be	AUX
bptjm-29	293	21	the	the	DET
bptjm-29	293	22	enzyme	enzyme	NOUN
bptjm-29	293	23	responsible	responsible	ADJ
bptjm-29	293	24	for	for	ADP
bptjm-29	293	25	the	the	DET
bptjm-29	293	26	region	region	NOUN
bptjm-29	293	27	of	of	ADP
bptjm-29	293	28	the	the	DET
bptjm-29	293	29	telomeric	telomeric	ADJ
bptjm-29	293	30	region	region	NOUN
bptjm-29	293	31	at	at	ADP
bptjm-29	293	32	the	the	DET
bptjm-29	293	33	3	3	NUM
bptjm-29	293	34	’	'	PUNCT
bptjm-29	293	35	ends	end	NOUN
bptjm-29	293	36	of	of	ADP
bptjm-29	293	37	chromosomes	chromosome	NOUN
bptjm-29	293	38	.	.	PUNCT
bptjm-29	294	1	telomeres	telomere	NOUN
bptjm-29	294	2	also	also	ADV
bptjm-29	294	3	protect	protect	VERB
bptjm-29	294	4	chromosomal	chromosomal	ADJ
bptjm-29	294	5	ends	end	NOUN
bptjm-29	294	6	from	from	ADP
bptjm-29	294	7	degradation	degradation	NOUN
bptjm-29	294	8	and	and	CCONJ
bptjm-29	294	9	improper	improper	ADJ
bptjm-29	294	10	dna	dna	NOUN
bptjm-29	294	11	recombination	recombination	NOUN
bptjm-29	294	12	(	(	PUNCT
bptjm-29	294	13	which	which	PRON
bptjm-29	294	14	can	can	AUX
bptjm-29	294	15	result	result	VERB
bptjm-29	294	16	in	in	ADP
bptjm-29	294	17	apoptosis	apoptosis	NOUN
bptjm-29	294	18	)	)	PUNCT
bptjm-29	294	19	.	.	PUNCT
bptjm-29	295	1	as	as	ADP
bptjm-29	295	2	such	such	ADJ
bptjm-29	295	3	,	,	PUNCT
bptjm-29	295	4	an	an	DET
bptjm-29	295	5	increased	increase	VERB
bptjm-29	295	6	telomerase	telomerase	NOUN
bptjm-29	295	7	activity	activity	NOUN
bptjm-29	295	8	is	be	AUX
bptjm-29	295	9	directly	directly	ADV
bptjm-29	295	10	correlated	correlate	VERB
bptjm-29	295	11	with	with	ADP
bptjm-29	295	12	a	a	DET
bptjm-29	295	13	longer	long	ADJ
bptjm-29	295	14	cell	cell	NOUN
bptjm-29	295	15	lifespan	lifespan	NOUN
bptjm-29	295	16	.	.	PUNCT
bptjm-29	296	1	since	since	SCONJ
bptjm-29	296	2	the	the	DET
bptjm-29	296	3	telomerase	telomerase	NOUN
bptjm-29	296	4	activity	activity	NOUN
bptjm-29	296	5	is	be	AUX
bptjm-29	296	6	augmented	augment	VERB
bptjm-29	296	7	within	within	ADP
bptjm-29	296	8	mscs	msc	NOUN
bptjm-29	296	9	,	,	PUNCT
bptjm-29	296	10	mscs	msc	NOUN
bptjm-29	296	11	have	have	VERB
bptjm-29	296	12	a	a	DET
bptjm-29	296	13	longer	long	ADJ
bptjm-29	296	14	period	period	NOUN
bptjm-29	296	15	of	of	ADP
bptjm-29	296	16	survival	survival	NOUN
bptjm-29	296	17	.	.	PUNCT
bptjm-29	297	1	the	the	DET
bptjm-29	297	2	telomerase	telomerase	NOUN
bptjm-29	297	3	activity	activity	NOUN
bptjm-29	297	4	and	and	CCONJ
bptjm-29	297	5	the	the	DET
bptjm-29	297	6	telomere	telomere	NOUN
bptjm-29	297	7	lengths	length	NOUN
bptjm-29	297	8	can	can	AUX
bptjm-29	297	9	also	also	ADV
bptjm-29	297	10	be	be	AUX
bptjm-29	297	11	analyzed	analyze	VERB
bptjm-29	297	12	as	as	ADP
bptjm-29	297	13	a	a	DET
bptjm-29	297	14	quality	quality	NOUN
bptjm-29	297	15	control	control	NOUN
bptjm-29	297	16	measure	measure	NOUN
bptjm-29	297	17	to	to	PART
bptjm-29	297	18	aid	aid	VERB
bptjm-29	297	19	in	in	ADP
bptjm-29	297	20	the	the	DET
bptjm-29	297	21	selection	selection	NOUN
bptjm-29	297	22	of	of	ADP
bptjm-29	297	23	mscs	msc	NOUN
bptjm-29	297	24	for	for	ADP
bptjm-29	297	25	therapeutic	therapeutic	ADJ
bptjm-29	297	26	applications	application	NOUN
bptjm-29	297	27	.	.	PUNCT
bptjm-29	298	1	studies	study	NOUN
bptjm-29	298	2	have	have	AUX
bptjm-29	298	3	demonstrated	demonstrate	VERB
bptjm-29	298	4	that	that	SCONJ
bptjm-29	298	5	mscs	msc	NOUN
bptjm-29	298	6	have	have	VERB
bptjm-29	298	7	the	the	DET
bptjm-29	298	8	capability	capability	NOUN
bptjm-29	298	9	and	and	CCONJ
bptjm-29	298	10	potential	potential	NOUN
bptjm-29	298	11	of	of	ADP
bptjm-29	298	12	being	be	AUX
bptjm-29	298	13	trans	trans	PROPN
bptjm-29	298	14	-	-	PROPN
bptjm-29	298	15	di	di	NOUN
bptjm-29	298	16	�	�	PROPN
bptjm-29	298	17	erentiated	erentiate	VERB
bptjm-29	298	18	into	into	ADP
bptjm-29	298	19	neuron	neuron	NOUN
bptjm-29	298	20	-	-	PUNCT
bptjm-29	298	21	like	like	ADJ
bptjm-29	298	22	cells	cell	NOUN
bptjm-29	298	23	;	;	PUNCT
bptjm-29	298	24	however	however	ADV
bptjm-29	298	25	,	,	PUNCT
bptjm-29	298	26	the	the	DET
bptjm-29	298	27	speci	speci	PROPN
bptjm-29	298	28	�	�	PROPN
bptjm-29	298	29	c	c	PROPN
bptjm-29	298	30	protocols	protocol	NOUN
bptjm-29	298	31	for	for	ADP
bptjm-29	298	32	inducing	induce	VERB
bptjm-29	298	33	this	this	DET
bptjm-29	298	34	di	di	NOUN
bptjm-29	298	35	�	�	PROPN
bptjm-29	298	36	erentiation	erentiation	NOUN
bptjm-29	298	37	involve	involve	VERB
bptjm-29	298	38	toxic	toxic	ADJ
bptjm-29	298	39	chemicals	chemical	NOUN
bptjm-29	298	40	and	and	CCONJ
bptjm-29	298	41	thus	thus	ADV
bptjm-29	298	42	can	can	AUX
bptjm-29	298	43	not	not	PART
bptjm-29	298	44	directly	directly	ADV
bptjm-29	298	45	be	be	AUX
bptjm-29	298	46	utilized	utilize	VERB
bptjm-29	298	47	within	within	ADP
bptjm-29	298	48	humans	human	NOUN
bptjm-29	298	49	.	.	PUNCT
bptjm-29	299	1	as	as	SCONJ
bptjm-29	299	2	such	such	ADJ
bptjm-29	299	3	,	,	PUNCT
bptjm-29	299	4	further	further	ADJ
bptjm-29	299	5	research	research	NOUN
bptjm-29	299	6	and	and	CCONJ
bptjm-29	299	7	study	study	NOUN
bptjm-29	299	8	of	of	ADP
bptjm-29	299	9	the	the	DET
bptjm-29	299	10	di	di	PROPN
bptjm-29	299	11	�	�	PROPN
bptjm-29	299	12	erentiability	erentiability	NOUN
bptjm-29	299	13	of	of	ADP
bptjm-29	299	14	mscs	msc	NOUN
bptjm-29	299	15	is	be	AUX
bptjm-29	299	16	warranted	warrant	VERB
bptjm-29	299	17	when	when	SCONJ
bptjm-29	299	18	considering	consider	VERB
bptjm-29	299	19	their	their	PRON
bptjm-29	299	20	potential	potential	NOUN
bptjm-29	299	21	as	as	ADP
bptjm-29	299	22	a	a	DET
bptjm-29	299	23	viable	viable	ADJ
bptjm-29	299	24	therapeutic	therapeutic	NOUN
bptjm-29	299	25	for	for	ADP
bptjm-29	299	26	als	al	NOUN
bptjm-29	299	27	and	and	CCONJ
bptjm-29	299	28	more	more	ADV
bptjm-29	299	29	broadly	broadly	ADV
bptjm-29	299	30	,	,	PUNCT
bptjm-29	299	31	neuron	neuron	NOUN
bptjm-29	299	32	degeneration	degeneration	NOUN
bptjm-29	299	33	.	.	PUNCT
bptjm-29	300	1	berkeley	berkeley	PROPN
bptjm-29	300	2	pharma	pharma	PROPN
bptjm-29	300	3	tech	tech	PROPN
bptjm-29	300	4	journal	journal	NOUN
bptjm-29	300	5	of	of	ADP
bptjm-29	300	6	medicine	medicine	NOUN
bptjm-29	300	7	|	|	ADV
bptjm-29	300	8	91	91	NUM
bptjm-29	300	9	https://www.zotero.org/google-docs/?iadymz	https://www.zotero.org/google-docs/?iadymz	NOUN
bptjm-29	300	10	7	7	NUM
bptjm-29	300	11	.	.	PUNCT
bptjm-29	300	12	mesenchymal	mesenchymal	ADJ
bptjm-29	300	13	stem	stem	NOUN
bptjm-29	300	14	cell	cell	NOUN
bptjm-29	300	15	treatment	treatment	NOUN
bptjm-29	300	16	for	for	ADP
bptjm-29	300	17	als	als	NOUN
bptjm-29	300	18	mesenchymal	mesenchymal	NOUN
bptjm-29	300	19	stem	stem	NOUN
bptjm-29	300	20	cells	cell	NOUN
bptjm-29	300	21	could	could	AUX
bptjm-29	300	22	be	be	AUX
bptjm-29	300	23	the	the	DET
bptjm-29	300	24	potential	potential	ADJ
bptjm-29	300	25	cure	cure	NOUN
bptjm-29	300	26	for	for	ADP
bptjm-29	300	27	als	al	NOUN
bptjm-29	300	28	not	not	PART
bptjm-29	300	29	only	only	ADV
bptjm-29	300	30	due	due	ADJ
bptjm-29	300	31	to	to	ADP
bptjm-29	300	32	its	its	PRON
bptjm-29	300	33	ability	ability	NOUN
bptjm-29	300	34	to	to	PART
bptjm-29	300	35	stimulate	stimulate	VERB
bptjm-29	300	36	tissue	tissue	NOUN
bptjm-29	300	37	repair	repair	NOUN
bptjm-29	300	38	by	by	ADP
bptjm-29	300	39	di	di	PROPN
bptjm-29	300	40	�	�	PROPN
bptjm-29	300	41	erentiating	erentiate	VERB
bptjm-29	300	42	into	into	ADP
bptjm-29	300	43	motor	motor	NOUN
bptjm-29	300	44	neurons	neuron	NOUN
bptjm-29	300	45	but	but	CCONJ
bptjm-29	300	46	also	also	ADV
bptjm-29	300	47	by	by	ADP
bptjm-29	300	48	repairing	repair	VERB
bptjm-29	300	49	damaged	damage	VERB
bptjm-29	300	50	cells	cell	NOUN
bptjm-29	300	51	within	within	ADP
bptjm-29	300	52	the	the	DET
bptjm-29	300	53	body	body	NOUN
bptjm-29	300	54	.	.	PUNCT
bptjm-29	301	1	mscs	msc	NOUN
bptjm-29	301	2	are	be	AUX
bptjm-29	301	3	especially	especially	ADV
bptjm-29	301	4	advantageous	advantageous	ADJ
bptjm-29	301	5	compared	compare	VERB
bptjm-29	301	6	to	to	ADP
bptjm-29	301	7	other	other	ADJ
bptjm-29	301	8	stem	stem	NOUN
bptjm-29	301	9	cells	cell	NOUN
bptjm-29	301	10	due	due	ADJ
bptjm-29	301	11	to	to	ADP
bptjm-29	301	12	many	many	ADJ
bptjm-29	301	13	of	of	ADP
bptjm-29	301	14	its	its	PRON
bptjm-29	301	15	properties	property	NOUN
bptjm-29	301	16	.	.	PUNCT
bptjm-29	302	1	one	one	NUM
bptjm-29	302	2	of	of	ADP
bptjm-29	302	3	these	these	DET
bptjm-29	302	4	advantages	advantage	NOUN
bptjm-29	302	5	include	include	VERB
bptjm-29	302	6	its	its	PRON
bptjm-29	302	7	great	great	ADJ
bptjm-29	302	8	availability	availability	NOUN
bptjm-29	302	9	—	—	PUNCT
bptjm-29	302	10	they	they	PRON
bptjm-29	302	11	can	can	AUX
bptjm-29	302	12	be	be	AUX
bptjm-29	302	13	derived	derive	VERB
bptjm-29	302	14	from	from	ADP
bptjm-29	302	15	adult	adult	NOUN
bptjm-29	302	16	tissue	tissue	NOUN
bptjm-29	302	17	such	such	ADJ
bptjm-29	302	18	as	as	ADP
bptjm-29	302	19	bone	bone	NOUN
bptjm-29	302	20	marrow	marrow	NOUN
bptjm-29	302	21	tissue	tissue	NOUN
bptjm-29	302	22	,	,	PUNCT
bptjm-29	302	23	skeletal	skeletal	ADJ
bptjm-29	302	24	tissue	tissue	NOUN
bptjm-29	302	25	,	,	PUNCT
bptjm-29	302	26	or	or	CCONJ
bptjm-29	302	27	adipose	adipose	X
bptjm-29	302	28	(	(	PUNCT
bptjm-29	302	29	fat	fat	ADJ
bptjm-29	302	30	)	)	PUNCT
bptjm-29	302	31	tissue	tissue	NOUN
bptjm-29	302	32	or	or	CCONJ
bptjm-29	302	33	can	can	AUX
bptjm-29	302	34	also	also	ADV
bptjm-29	302	35	be	be	AUX
bptjm-29	302	36	derived	derive	VERB
bptjm-29	302	37	from	from	ADP
bptjm-29	302	38	fetal	fetal	ADJ
bptjm-29	302	39	tissue	tissue	NOUN
bptjm-29	302	40	such	such	ADJ
bptjm-29	302	41	as	as	ADP
bptjm-29	302	42	the	the	DET
bptjm-29	302	43	placenta	placenta	NOUN
bptjm-29	302	44	or	or	CCONJ
bptjm-29	302	45	umbilical	umbilical	ADJ
bptjm-29	302	46	cord	cord	NOUN
bptjm-29	302	47	.	.	PUNCT
bptjm-29	303	1	because	because	SCONJ
bptjm-29	303	2	of	of	ADP
bptjm-29	303	3	these	these	DET
bptjm-29	303	4	speci	speci	PROPN
bptjm-29	303	5	�	�	PROPN
bptjm-29	303	6	c	c	NOUN
bptjm-29	303	7	tissue	tissue	NOUN
bptjm-29	303	8	sources	source	NOUN
bptjm-29	303	9	,	,	PUNCT
bptjm-29	303	10	mscs	msc	NOUN
bptjm-29	303	11	can	can	AUX
bptjm-29	303	12	be	be	AUX
bptjm-29	303	13	found	find	VERB
bptjm-29	303	14	in	in	ADP
bptjm-29	303	15	abundance	abundance	NOUN
bptjm-29	303	16	,	,	PUNCT
bptjm-29	303	17	especially	especially	ADV
bptjm-29	303	18	due	due	ADP
bptjm-29	303	19	to	to	ADP
bptjm-29	303	20	the	the	DET
bptjm-29	303	21	medical	medical	ADJ
bptjm-29	303	22	waste	waste	NOUN
bptjm-29	303	23	created	create	VERB
bptjm-29	303	24	from	from	ADP
bptjm-29	303	25	these	these	DET
bptjm-29	303	26	tissues	tissue	NOUN
bptjm-29	303	27	.	.	PUNCT
bptjm-29	304	1	for	for	ADP
bptjm-29	304	2	example	example	NOUN
bptjm-29	304	3	,	,	PUNCT
bptjm-29	304	4	adipose	adipose	ADJ
bptjm-29	304	5	tissue	tissue	NOUN
bptjm-29	304	6	can	can	AUX
bptjm-29	304	7	be	be	AUX
bptjm-29	304	8	obtained	obtain	VERB
bptjm-29	304	9	from	from	ADP
bptjm-29	304	10	liposuction	liposuction	NOUN
bptjm-29	304	11	while	while	SCONJ
bptjm-29	304	12	the	the	DET
bptjm-29	304	13	placenta	placenta	NOUN
bptjm-29	304	14	is	be	AUX
bptjm-29	304	15	delivered	deliver	VERB
bptjm-29	304	16	and	and	CCONJ
bptjm-29	304	17	most	most	ADJ
bptjm-29	304	18	of	of	ADP
bptjm-29	304	19	the	the	DET
bptjm-29	304	20	time	time	NOUN
bptjm-29	304	21	gotten	get	VERB
bptjm-29	304	22	rid	rid	ADJ
bptjm-29	304	23	of	of	ADP
bptjm-29	304	24	.	.	PUNCT
bptjm-29	305	1	however	however	ADV
bptjm-29	305	2	,	,	PUNCT
bptjm-29	305	3	bone	bone	NOUN
bptjm-29	305	4	marrow	marrow	NOUN
bptjm-29	305	5	tissue	tissue	NOUN
bptjm-29	305	6	—	—	PUNCT
bptjm-29	305	7	the	the	DET
bptjm-29	305	8	soft	soft	ADJ
bptjm-29	305	9	,	,	PUNCT
bptjm-29	305	10	spongy	spongy	ADJ
bptjm-29	305	11	tissue	tissue	NOUN
bptjm-29	305	12	found	find	VERB
bptjm-29	305	13	inside	inside	ADP
bptjm-29	305	14	the	the	DET
bptjm-29	305	15	bone	bone	NOUN
bptjm-29	305	16	and	and	CCONJ
bptjm-29	305	17	contains	contain	VERB
bptjm-29	305	18	stem	stem	NOUN
bptjm-29	305	19	cells62	cells62	NOUN
bptjm-29	305	20	—	—	PUNCT
bptjm-29	305	21	can	can	AUX
bptjm-29	305	22	be	be	AUX
bptjm-29	305	23	obtained	obtain	VERB
bptjm-29	305	24	in	in	ADP
bptjm-29	305	25	the	the	DET
bptjm-29	305	26	most	most	ADJ
bptjm-29	305	27	abundance	abundance	NOUN
bptjm-29	305	28	and	and	CCONJ
bptjm-29	305	29	is	be	AUX
bptjm-29	305	30	even	even	ADV
bptjm-29	305	31	possible	possible	ADJ
bptjm-29	305	32	to	to	PART
bptjm-29	305	33	be	be	AUX
bptjm-29	305	34	extracted	extract	VERB
bptjm-29	305	35	from	from	ADP
bptjm-29	305	36	the	the	DET
bptjm-29	305	37	patient	patient	NOUN
bptjm-29	305	38	itself	itself	PRON
bptjm-29	305	39	to	to	PART
bptjm-29	305	40	mitigate	mitigate	VERB
bptjm-29	305	41	the	the	DET
bptjm-29	305	42	chance	chance	NOUN
bptjm-29	305	43	of	of	ADP
bptjm-29	305	44	rejection	rejection	NOUN
bptjm-29	305	45	by	by	ADP
bptjm-29	305	46	the	the	DET
bptjm-29	305	47	host	host	NOUN
bptjm-29	305	48	.	.	PUNCT
bptjm-29	306	1	although	although	SCONJ
bptjm-29	306	2	mscs	msc	NOUN
bptjm-29	306	3	are	be	AUX
bptjm-29	306	4	multipotent	multipotent	NOUN
bptjm-29	306	5	,	,	PUNCT
bptjm-29	306	6	they	they	PRON
bptjm-29	306	7	can	can	AUX
bptjm-29	306	8	exhibit	exhibit	VERB
bptjm-29	306	9	pluripotent	pluripotent	ADJ
bptjm-29	306	10	properties63	properties63	NOUN
bptjm-29	306	11	.	.	PUNCT
bptjm-29	307	1	there	there	PRON
bptjm-29	307	2	is	be	VERB
bptjm-29	307	3	growing	grow	VERB
bptjm-29	307	4	evidence	evidence	NOUN
bptjm-29	307	5	that	that	SCONJ
bptjm-29	307	6	mscs	msc	NOUN
bptjm-29	307	7	can	can	AUX
bptjm-29	307	8	transdi	transdi	VERB
bptjm-29	307	9	�	�	PROPN
bptjm-29	307	10	erentiate	erentiate	NOUN
bptjm-29	307	11	into	into	ADP
bptjm-29	307	12	motor	motor	NOUN
bptjm-29	307	13	neurons	neuron	NOUN
bptjm-29	307	14	.	.	PUNCT
bptjm-29	308	1	one	one	NUM
bptjm-29	308	2	study	study	NOUN
bptjm-29	308	3	shows	show	VERB
bptjm-29	308	4	that	that	SCONJ
bptjm-29	308	5	a	a	DET
bptjm-29	308	6	cocktail	cocktail	NOUN
bptjm-29	308	7	of	of	ADP
bptjm-29	308	8	basic	basic	ADJ
bptjm-29	308	9	�	�	PROPN
bptjm-29	308	10	broblast	broblast	ADJ
bptjm-29	308	11	growth	growth	NOUN
bptjm-29	308	12	factor	factor	NOUN
bptjm-29	308	13	(	(	PUNCT
bptjm-29	308	14	bfgf	bfgf	NOUN
bptjm-29	308	15	)	)	PUNCT
bptjm-29	308	16	and	and	CCONJ
bptjm-29	308	17	retinoic	retinoic	PROPN
bptjm-29	308	18	acid	acid	PROPN
bptjm-29	308	19	(	(	PUNCT
bptjm-29	308	20	ra	ra	NOUN
bptjm-29	308	21	)	)	PUNCT
bptjm-29	308	22	with	with	ADP
bptjm-29	308	23	human	human	ADJ
bptjm-29	308	24	mscs	msc	NOUN
bptjm-29	308	25	(	(	PUNCT
bptjm-29	308	26	hmsc	hmsc	NOUN
bptjm-29	308	27	)	)	PUNCT
bptjm-29	308	28	provide	provide	VERB
bptjm-29	308	29	the	the	DET
bptjm-29	308	30	most	most	ADJ
bptjm-29	308	31	e	e	NOUN
bptjm-29	308	32	�	�	NOUN
bptjm-29	308	33	ective	ective	ADJ
bptjm-29	308	34	and	and	CCONJ
bptjm-29	308	35	e	e	NOUN
bptjm-29	308	36	�	�	PROPN
bptjm-29	308	37	cient	cient	PROPN
bptjm-29	308	38	transdi	transdi	NOUN
bptjm-29	308	39	�	�	PROPN
bptjm-29	308	40	erentiation	erentiation	NOUN
bptjm-29	308	41	of	of	ADP
bptjm-29	308	42	msc	msc	PROPN
bptjm-29	308	43	into	into	ADP
bptjm-29	308	44	neural	neural	ADJ
bptjm-29	308	45	cells64	cells64	NOUN
bptjm-29	308	46	.	.	PUNCT
bptjm-29	309	1	two	two	NUM
bptjm-29	309	2	days	day	NOUN
bptjm-29	309	3	after	after	ADP
bptjm-29	309	4	injection	injection	NOUN
bptjm-29	309	5	of	of	ADP
bptjm-29	309	6	these	these	DET
bptjm-29	309	7	cells	cell	NOUN
bptjm-29	309	8	,	,	PUNCT
bptjm-29	309	9	these	these	DET
bptjm-29	309	10	cells	cell	NOUN
bptjm-29	309	11	expressed	express	VERB
bptjm-29	309	12	glial	glial	ADJ
bptjm-29	309	13	markers	marker	NOUN
bptjm-29	309	14	,	,	PUNCT
bptjm-29	309	15	and	and	CCONJ
bptjm-29	309	16	12	12	NUM
bptjm-29	309	17	days	day	NOUN
bptjm-29	309	18	after	after	ADP
bptjm-29	309	19	injection	injection	NOUN
bptjm-29	309	20	,	,	PUNCT
bptjm-29	309	21	90	90	NUM
bptjm-29	309	22	%	%	NOUN
bptjm-29	309	23	of	of	ADP
bptjm-29	309	24	the	the	DET
bptjm-29	309	25	hmscs	hmscs	PROPN
bptjm-29	309	26	di	di	NOUN
bptjm-29	309	27	�	�	PROPN
bptjm-29	309	28	erentiated	erentiate	VERB
bptjm-29	309	29	into	into	ADP
bptjm-29	309	30	cells	cell	NOUN
bptjm-29	309	31	that	that	PRON
bptjm-29	309	32	expressed	express	VERB
bptjm-29	309	33	neuronal	neuronal	ADJ
bptjm-29	309	34	markers	marker	NOUN
bptjm-29	309	35	,	,	PUNCT
bptjm-29	309	36	which	which	PRON
bptjm-29	309	37	also	also	ADV
bptjm-29	309	38	include	include	VERB
bptjm-29	309	39	transcription	transcription	NOUN
bptjm-29	309	40	factors	factor	NOUN
bptjm-29	309	41	linked	link	VERB
bptjm-29	309	42	to	to	PART
bptjm-29	309	43	aid	aid	VERB
bptjm-29	309	44	the	the	DET
bptjm-29	309	45	development	development	NOUN
bptjm-29	309	46	of	of	ADP
bptjm-29	309	47	the	the	DET
bptjm-29	309	48	di	di	PROPN
bptjm-29	309	49	�	�	PROPN
bptjm-29	309	50	erentiated	erentiate	VERB
bptjm-29	309	51	neurons65	neurons65	NOUN
bptjm-29	309	52	.	.	PUNCT
bptjm-29	310	1	this	this	DET
bptjm-29	310	2	con	con	PROPN
bptjm-29	310	3	�	�	PROPN
bptjm-29	310	4	rmed	rme	VERB
bptjm-29	310	5	the	the	DET
bptjm-29	310	6	ability	ability	NOUN
bptjm-29	310	7	of	of	ADP
bptjm-29	310	8	mscs	msc	NOUN
bptjm-29	310	9	to	to	PART
bptjm-29	310	10	be	be	AUX
bptjm-29	310	11	able	able	ADJ
bptjm-29	310	12	to	to	PART
bptjm-29	310	13	di	di	VERB
bptjm-29	310	14	�	�	PROPN
bptjm-29	310	15	erentiate	erentiate	NOUN
bptjm-29	310	16	into	into	ADP
bptjm-29	310	17	neurons	neuron	NOUN
bptjm-29	310	18	,	,	PUNCT
bptjm-29	310	19	providing	provide	VERB
bptjm-29	310	20	a	a	DET
bptjm-29	310	21	method	method	NOUN
bptjm-29	310	22	to	to	PART
bptjm-29	310	23	stimulate	stimulate	VERB
bptjm-29	310	24	tissue	tissue	NOUN
bptjm-29	310	25	repair	repair	NOUN
bptjm-29	310	26	.	.	PUNCT
bptjm-29	311	1	after	after	ADP
bptjm-29	311	2	being	be	AUX
bptjm-29	311	3	injected	inject	VERB
bptjm-29	311	4	intrathecally	intrathecally	ADV
bptjm-29	311	5	,	,	PUNCT
bptjm-29	311	6	in	in	ADP
bptjm-29	311	7	order	order	NOUN
bptjm-29	311	8	for	for	SCONJ
bptjm-29	311	9	the	the	DET
bptjm-29	311	10	mscs	msc	NOUN
bptjm-29	311	11	to	to	PART
bptjm-29	311	12	di	di	VERB
bptjm-29	311	13	�	�	PROPN
bptjm-29	311	14	erentiate	erentiate	NOUN
bptjm-29	311	15	and	and	CCONJ
bptjm-29	311	16	develop	develop	VERB
bptjm-29	311	17	in	in	ADP
bptjm-29	311	18	the	the	DET
bptjm-29	311	19	correct	correct	ADJ
bptjm-29	311	20	area	area	NOUN
bptjm-29	311	21	,	,	PUNCT
bptjm-29	311	22	als	als	NOUN
bptjm-29	311	23	allows	allow	VERB
bptjm-29	311	24	for	for	ADP
bptjm-29	311	25	an	an	DET
bptjm-29	311	26	e	e	NOUN
bptjm-29	311	27	�	�	NOUN
bptjm-29	311	28	ective	ective	ADJ
bptjm-29	311	29	stimulus	stimulus	NOUN
bptjm-29	311	30	.	.	PUNCT
bptjm-29	312	1	a	a	DET
bptjm-29	312	2	key	key	ADJ
bptjm-29	312	3	advantage	advantage	NOUN
bptjm-29	312	4	of	of	ADP
bptjm-29	312	5	mscs	msc	NOUN
bptjm-29	312	6	over	over	ADP
bptjm-29	312	7	similar	similar	ADJ
bptjm-29	312	8	forms	form	NOUN
bptjm-29	312	9	of	of	ADP
bptjm-29	312	10	stem	stem	NOUN
bptjm-29	312	11	cells	cell	NOUN
bptjm-29	312	12	is	be	AUX
bptjm-29	312	13	their	their	PRON
bptjm-29	312	14	ability	ability	NOUN
bptjm-29	312	15	to	to	PART
bptjm-29	312	16	migrate	migrate	VERB
bptjm-29	312	17	towards	towards	ADP
bptjm-29	312	18	in	in	ADP
bptjm-29	312	19	�	�	NOUN
bptjm-29	312	20	ammatory	ammatory	NOUN
bptjm-29	312	21	foci	focus	NOUN
bptjm-29	312	22	through	through	ADP
bptjm-29	312	23	the	the	DET
bptjm-29	312	24	expression	expression	NOUN
bptjm-29	312	25	of	of	ADP
bptjm-29	312	26	chemokine	chemokine	ADJ
bptjm-29	312	27	receptors	receptor	NOUN
bptjm-29	312	28	,	,	PUNCT
bptjm-29	312	29	and	and	CCONJ
bptjm-29	312	30	as	as	ADP
bptjm-29	312	31	a	a	DET
bptjm-29	312	32	pathogenetic	pathogenetic	ADJ
bptjm-29	312	33	mechanism	mechanism	NOUN
bptjm-29	312	34	of	of	ADP
bptjm-29	312	35	als	al	NOUN
bptjm-29	312	36	,	,	PUNCT
bptjm-29	312	37	in	in	ADP
bptjm-29	312	38	�	�	PROPN
bptjm-29	312	39	ammation	ammation	NOUN
bptjm-29	312	40	provides	provide	VERB
bptjm-29	312	41	mscs	msc	NOUN
bptjm-29	312	42	the	the	DET
bptjm-29	312	43	knowledge	knowledge	NOUN
bptjm-29	312	44	of	of	ADP
bptjm-29	312	45	the	the	DET
bptjm-29	312	46	damaged	damage	VERB
bptjm-29	312	47	site66	site66	NOUN
bptjm-29	312	48	.	.	PUNCT
bptjm-29	313	1	chemokines	chemokine	NOUN
bptjm-29	313	2	are	be	AUX
bptjm-29	313	3	a	a	DET
bptjm-29	313	4	family	family	NOUN
bptjm-29	313	5	of	of	ADP
bptjm-29	313	6	cytokines	cytokine	NOUN
bptjm-29	313	7	which	which	PRON
bptjm-29	313	8	stimulate	stimulate	VERB
bptjm-29	313	9	white	white	ADJ
bptjm-29	313	10	blood	blood	NOUN
bptjm-29	313	11	cell	cell	NOUN
bptjm-29	313	12	migration	migration	NOUN
bptjm-29	313	13	to	to	ADP
bptjm-29	313	14	sites	site	NOUN
bptjm-29	313	15	of	of	ADP
bptjm-29	313	16	infection	infection	NOUN
bptjm-29	313	17	and	and	CCONJ
bptjm-29	313	18	thus	thus	ADV
bptjm-29	313	19	berkeley	berkeley	PROPN
bptjm-29	313	20	pharma	pharma	PROPN
bptjm-29	313	21	tech	tech	NOUN
bptjm-29	313	22	journal	journal	NOUN
bptjm-29	313	23	of	of	ADP
bptjm-29	313	24	medicine	medicine	NOUN
bptjm-29	313	25	|	|	ADV
bptjm-29	313	26	92	92	NUM
bptjm-29	313	27	https://www.zotero.org/google-docs/?17ayui	https://www.zotero.org/google-docs/?17ayui	PROPN
bptjm-29	313	28	https://www.zotero.org/google-docs/?wftqzr	https://www.zotero.org/google-docs/?wftqzr	ADJ
bptjm-29	313	29	https://www.zotero.org/google-docs/?8teuq4	https://www.zotero.org/google-docs/?8teuq4	PROPN
bptjm-29	313	30	https://www.zotero.org/google-docs/?flgw3j	https://www.zotero.org/google-docs/?flgw3j	PROPN
bptjm-29	313	31	https://www.zotero.org/google-docs/?zsm4np	https://www.zotero.org/google-docs/?zsm4np	PROPN
bptjm-29	313	32	play	play	VERB
bptjm-29	313	33	an	an	DET
bptjm-29	313	34	integral	integral	ADJ
bptjm-29	313	35	role	role	NOUN
bptjm-29	313	36	in	in	ADP
bptjm-29	313	37	the	the	DET
bptjm-29	313	38	homeostasis	homeostasis	NOUN
bptjm-29	313	39	of	of	ADP
bptjm-29	313	40	the	the	DET
bptjm-29	313	41	immune	immune	ADJ
bptjm-29	313	42	system67	system67	NOUN
bptjm-29	313	43	.	.	PUNCT
bptjm-29	314	1	chemokine	chemokine	ADJ
bptjm-29	314	2	receptors	receptor	NOUN
bptjm-29	314	3	interact	interact	VERB
bptjm-29	314	4	with	with	ADP
bptjm-29	314	5	the	the	DET
bptjm-29	314	6	chemokines	chemokine	NOUN
bptjm-29	314	7	,	,	PUNCT
bptjm-29	314	8	themselves	themselves	PRON
bptjm-29	314	9	,	,	PUNCT
bptjm-29	314	10	in	in	ADP
bptjm-29	314	11	order	order	NOUN
bptjm-29	314	12	to	to	PART
bptjm-29	314	13	manage	manage	VERB
bptjm-29	314	14	the	the	DET
bptjm-29	314	15	function	function	NOUN
bptjm-29	314	16	of	of	ADP
bptjm-29	314	17	the	the	DET
bptjm-29	314	18	immune	immune	ADJ
bptjm-29	314	19	system	system	NOUN
bptjm-29	314	20	;	;	PUNCT
bptjm-29	314	21	it	it	PRON
bptjm-29	314	22	is	be	AUX
bptjm-29	314	23	thus	thus	ADV
bptjm-29	314	24	evident	evident	ADJ
bptjm-29	314	25	that	that	SCONJ
bptjm-29	314	26	the	the	DET
bptjm-29	314	27	expression	expression	NOUN
bptjm-29	314	28	of	of	ADP
bptjm-29	314	29	chemokine	chemokine	ADJ
bptjm-29	314	30	receptors	receptor	NOUN
bptjm-29	314	31	by	by	ADP
bptjm-29	314	32	mscs	msc	NOUN
bptjm-29	314	33	plays	play	VERB
bptjm-29	314	34	a	a	DET
bptjm-29	314	35	key	key	ADJ
bptjm-29	314	36	role	role	NOUN
bptjm-29	314	37	in	in	ADP
bptjm-29	314	38	the	the	DET
bptjm-29	314	39	reduction	reduction	NOUN
bptjm-29	314	40	of	of	ADP
bptjm-29	314	41	in	in	ADP
bptjm-29	314	42	�	�	PROPN
bptjm-29	314	43	ammation	ammation	NOUN
bptjm-29	314	44	to	to	PART
bptjm-29	314	45	maintain	maintain	VERB
bptjm-29	314	46	equilibrium	equilibrium	NOUN
bptjm-29	314	47	within	within	ADP
bptjm-29	314	48	the	the	DET
bptjm-29	314	49	immune	immune	ADJ
bptjm-29	314	50	system	system	NOUN
bptjm-29	314	51	.	.	PUNCT
bptjm-29	315	1	figure	figure	NOUN
bptjm-29	315	2	3	3	NUM
bptjm-29	315	3	.	.	PUNCT
bptjm-29	315	4	mesenchymal	mesenchymal	ADJ
bptjm-29	315	5	stem	stem	NOUN
bptjm-29	315	6	cells	cell	NOUN
bptjm-29	315	7	are	be	AUX
bptjm-29	315	8	extracted	extract	VERB
bptjm-29	315	9	from	from	ADP
bptjm-29	315	10	bone	bone	NOUN
bptjm-29	315	11	marrow	marrow	NOUN
bptjm-29	315	12	and	and	CCONJ
bptjm-29	315	13	are	be	AUX
bptjm-29	315	14	intrathecally	intrathecally	ADV
bptjm-29	315	15	injected	inject	VERB
bptjm-29	315	16	into	into	ADP
bptjm-29	315	17	the	the	DET
bptjm-29	315	18	lateral	lateral	ADJ
bptjm-29	315	19	spinal	spinal	NOUN
bptjm-29	315	20	cord	cord	NOUN
bptjm-29	315	21	,	,	PUNCT
bptjm-29	315	22	where	where	SCONJ
bptjm-29	315	23	they	they	PRON
bptjm-29	315	24	can	can	AUX
bptjm-29	315	25	transdifferentiate	transdifferentiate	VERB
bptjm-29	315	26	into	into	ADP
bptjm-29	315	27	motor	motor	NOUN
bptjm-29	315	28	neurons	neuron	NOUN
bptjm-29	315	29	.	.	PUNCT
bptjm-29	316	1	mscs	msc	NOUN
bptjm-29	316	2	not	not	PART
bptjm-29	316	3	only	only	ADV
bptjm-29	316	4	stimulate	stimulate	VERB
bptjm-29	316	5	tissue	tissue	NOUN
bptjm-29	316	6	repair	repair	NOUN
bptjm-29	316	7	by	by	ADP
bptjm-29	316	8	di	di	PROPN
bptjm-29	316	9	�	�	PROPN
bptjm-29	316	10	erentiating	erentiate	VERB
bptjm-29	316	11	into	into	ADP
bptjm-29	316	12	motor	motor	PROPN
bptjm-29	316	13	neuron	neuron	NOUN
bptjm-29	316	14	cells	cell	NOUN
bptjm-29	316	15	but	but	CCONJ
bptjm-29	316	16	can	can	AUX
bptjm-29	316	17	also	also	ADV
bptjm-29	316	18	repair	repair	VERB
bptjm-29	316	19	damaged	damaged	ADJ
bptjm-29	316	20	cells	cell	NOUN
bptjm-29	316	21	and	and	CCONJ
bptjm-29	316	22	prevent	prevent	VERB
bptjm-29	316	23	motor	motor	NOUN
bptjm-29	316	24	neuron	neuron	NOUN
bptjm-29	316	25	degeneration	degeneration	NOUN
bptjm-29	316	26	from	from	ADP
bptjm-29	316	27	taking	take	VERB
bptjm-29	316	28	place	place	NOUN
bptjm-29	316	29	to	to	PART
bptjm-29	316	30	cure	cure	VERB
bptjm-29	316	31	the	the	DET
bptjm-29	316	32	disease	disease	NOUN
bptjm-29	316	33	.	.	PUNCT
bptjm-29	317	1	human	human	ADJ
bptjm-29	317	2	and	and	CCONJ
bptjm-29	317	3	animal	animal	NOUN
bptjm-29	317	4	mscs	msc	NOUN
bptjm-29	317	5	showed	show	VERB
bptjm-29	317	6	promising	promising	ADJ
bptjm-29	317	7	results	result	NOUN
bptjm-29	317	8	in	in	ADP
bptjm-29	317	9	regard	regard	NOUN
bptjm-29	317	10	to	to	ADP
bptjm-29	317	11	using	use	VERB
bptjm-29	317	12	these	these	DET
bptjm-29	317	13	stem	stem	NOUN
bptjm-29	317	14	cells	cell	NOUN
bptjm-29	317	15	for	for	ADP
bptjm-29	317	16	neural	neural	ADJ
bptjm-29	317	17	repair	repair	NOUN
bptjm-29	317	18	and	and	CCONJ
bptjm-29	317	19	not	not	PART
bptjm-29	317	20	just	just	ADV
bptjm-29	317	21	to	to	PART
bptjm-29	317	22	replace	replace	VERB
bptjm-29	317	23	the	the	DET
bptjm-29	317	24	damaged	damage	VERB
bptjm-29	317	25	motor	motor	NOUN
bptjm-29	317	26	neurons	neuron	NOUN
bptjm-29	317	27	.	.	PUNCT
bptjm-29	318	1	one	one	NUM
bptjm-29	318	2	way	way	NOUN
bptjm-29	318	3	mscs	msc	NOUN
bptjm-29	318	4	do	do	AUX
bptjm-29	318	5	this	this	PRON
bptjm-29	318	6	is	be	AUX
bptjm-29	318	7	by	by	ADP
bptjm-29	318	8	producing	produce	VERB
bptjm-29	318	9	trophic	trophic	ADJ
bptjm-29	318	10	factors	factor	NOUN
bptjm-29	318	11	,	,	PUNCT
bptjm-29	318	12	which	which	PRON
bptjm-29	318	13	can	can	AUX
bptjm-29	318	14	repair	repair	VERB
bptjm-29	318	15	or	or	CCONJ
bptjm-29	318	16	regenerate	regenerate	ADJ
bptjm-29	318	17	tissue68,69	tissue68,69	VERB
bptjm-29	318	18	.	.	PUNCT
bptjm-29	318	19	trophic	trophic	ADJ
bptjm-29	318	20	factors	factor	NOUN
bptjm-29	318	21	are	be	AUX
bptjm-29	318	22	helper	helper	NOUN
bptjm-29	318	23	molecules	molecule	NOUN
bptjm-29	318	24	that	that	PRON
bptjm-29	318	25	allow	allow	VERB
bptjm-29	318	26	neurons	neuron	NOUN
bptjm-29	318	27	to	to	PART
bptjm-29	318	28	develop	develop	VERB
bptjm-29	318	29	and	and	CCONJ
bptjm-29	318	30	maintain	maintain	VERB
bptjm-29	318	31	connections	connection	NOUN
bptjm-29	318	32	with	with	ADP
bptjm-29	318	33	their	their	PRON
bptjm-29	318	34	neighbors	neighbor	NOUN
bptjm-29	318	35	.	.	PUNCT
bptjm-29	319	1	they	they	PRON
bptjm-29	319	2	help	help	VERB
bptjm-29	319	3	establish	establish	VERB
bptjm-29	319	4	the	the	DET
bptjm-29	319	5	connection	connection	NOUN
bptjm-29	319	6	and	and	CCONJ
bptjm-29	319	7	allow	allow	VERB
bptjm-29	319	8	motor	motor	NOUN
bptjm-29	319	9	neurons	neuron	NOUN
bptjm-29	319	10	to	to	PART
bptjm-29	319	11	communicate	communicate	VERB
bptjm-29	319	12	with	with	ADP
bptjm-29	319	13	their	their	PRON
bptjm-29	319	14	target	target	NOUN
bptjm-29	319	15	cell	cell	NOUN
bptjm-29	319	16	,	,	PUNCT
bptjm-29	319	17	skeletal	skeletal	ADJ
bptjm-29	319	18	muscle	muscle	NOUN
bptjm-29	319	19	cells	cell	NOUN
bptjm-29	319	20	.	.	PUNCT
bptjm-29	320	1	they	they	PRON
bptjm-29	320	2	help	help	VERB
bptjm-29	320	3	maintain	maintain	VERB
bptjm-29	320	4	and	and	CCONJ
bptjm-29	320	5	support	support	VERB
bptjm-29	320	6	motor	motor	NOUN
bptjm-29	320	7	neurons	neuron	NOUN
bptjm-29	320	8	and	and	CCONJ
bptjm-29	320	9	also	also	ADV
bptjm-29	320	10	aid	aid	VERB
bptjm-29	320	11	in	in	ADP
bptjm-29	320	12	repairing	repair	VERB
bptjm-29	320	13	damaged	damage	VERB
bptjm-29	320	14	motor	motor	NOUN
bptjm-29	320	15	neurons	neuron	NOUN
bptjm-29	320	16	back	back	ADV
bptjm-29	320	17	to	to	ADP
bptjm-29	320	18	a	a	DET
bptjm-29	320	19	healthy	healthy	ADJ
bptjm-29	320	20	condition23	condition23	NOUN
bptjm-29	320	21	.	.	PUNCT
bptjm-29	321	1	however	however	ADV
bptjm-29	321	2	,	,	PUNCT
bptjm-29	321	3	although	although	SCONJ
bptjm-29	321	4	animal	animal	NOUN
bptjm-29	321	5	trials	trial	NOUN
bptjm-29	321	6	were	be	AUX
bptjm-29	321	7	successful	successful	ADJ
bptjm-29	321	8	in	in	ADP
bptjm-29	321	9	proving	prove	VERB
bptjm-29	321	10	the	the	DET
bptjm-29	321	11	healing	healing	NOUN
bptjm-29	321	12	properties	property	NOUN
bptjm-29	321	13	of	of	ADP
bptjm-29	321	14	these	these	DET
bptjm-29	321	15	factors	factor	NOUN
bptjm-29	321	16	,	,	PUNCT
bptjm-29	321	17	human	human	ADJ
bptjm-29	321	18	trials	trial	NOUN
bptjm-29	321	19	did	do	AUX
bptjm-29	321	20	not	not	PART
bptjm-29	321	21	produce	produce	VERB
bptjm-29	321	22	the	the	DET
bptjm-29	321	23	same	same	ADJ
bptjm-29	321	24	success	success	NOUN
bptjm-29	321	25	and	and	CCONJ
bptjm-29	321	26	need	need	VERB
bptjm-29	321	27	to	to	PART
bptjm-29	321	28	be	be	AUX
bptjm-29	321	29	further	far	ADV
bptjm-29	321	30	researched	research	VERB
bptjm-29	321	31	due	due	ADP
bptjm-29	321	32	to	to	ADP
bptjm-29	321	33	the	the	DET
bptjm-29	321	34	factors	factor	NOUN
bptjm-29	321	35	’	'	PUNCT
bptjm-29	321	36	inability	inability	NOUN
bptjm-29	321	37	to	to	PART
bptjm-29	321	38	reach	reach	VERB
bptjm-29	321	39	the	the	DET
bptjm-29	321	40	target	target	NOUN
bptjm-29	321	41	cell	cell	NOUN
bptjm-29	321	42	but	but	CCONJ
bptjm-29	321	43	large	large	ADJ
bptjm-29	321	44	amounts	amount	NOUN
bptjm-29	321	45	being	be	AUX
bptjm-29	321	46	too	too	ADV
bptjm-29	321	47	harmful	harmful	ADJ
bptjm-29	321	48	.	.	PUNCT
bptjm-29	322	1	another	another	DET
bptjm-29	322	2	way	way	NOUN
bptjm-29	322	3	mscs	msc	NOUN
bptjm-29	322	4	help	help	VERB
bptjm-29	322	5	repair	repair	VERB
bptjm-29	322	6	damaged	damage	VERB
bptjm-29	322	7	motor	motor	NOUN
bptjm-29	322	8	neurons	neuron	NOUN
bptjm-29	322	9	is	be	AUX
bptjm-29	322	10	through	through	ADP
bptjm-29	322	11	mitochondrial	mitochondrial	ADJ
bptjm-29	322	12	transfer	transfer	NOUN
bptjm-29	322	13	.	.	PUNCT
bptjm-29	323	1	the	the	DET
bptjm-29	323	2	use	use	NOUN
bptjm-29	323	3	of	of	ADP
bptjm-29	323	4	mitochondrial	mitochondrial	ADJ
bptjm-29	323	5	transfer	transfer	NOUN
bptjm-29	323	6	can	can	AUX
bptjm-29	323	7	aid	aid	VERB
bptjm-29	323	8	in	in	ADP
bptjm-29	323	9	tissue	tissue	NOUN
bptjm-29	323	10	regeneration	regeneration	NOUN
bptjm-29	323	11	and	and	CCONJ
bptjm-29	323	12	repair	repair	NOUN
bptjm-29	323	13	,	,	PUNCT
bptjm-29	323	14	and	and	CCONJ
bptjm-29	323	15	can	can	AUX
bptjm-29	323	16	also	also	ADV
bptjm-29	323	17	restore	restore	VERB
bptjm-29	323	18	the	the	DET
bptjm-29	323	19	bioenergetic	bioenergetic	ADJ
bptjm-29	323	20	needs	need	NOUN
bptjm-29	323	21	of	of	ADP
bptjm-29	323	22	damaged	damaged	ADJ
bptjm-29	323	23	cells70	cells70	NOUN
bptjm-29	323	24	.	.	PUNCT
bptjm-29	324	1	this	this	DET
bptjm-29	324	2	transfer	transfer	NOUN
bptjm-29	324	3	primarily	primarily	ADV
bptjm-29	324	4	occurs	occur	VERB
bptjm-29	324	5	through	through	ADP
bptjm-29	324	6	the	the	DET
bptjm-29	324	7	formation	formation	NOUN
bptjm-29	324	8	of	of	ADP
bptjm-29	324	9	intracellular	intracellular	ADJ
bptjm-29	324	10	nanotubes	nanotube	NOUN
bptjm-29	324	11	,	,	PUNCT
bptjm-29	324	12	gap	gap	NOUN
bptjm-29	324	13	junctions	junction	NOUN
bptjm-29	324	14	,	,	PUNCT
bptjm-29	324	15	and	and	CCONJ
bptjm-29	324	16	microvesicles	microvesicle	NOUN
bptjm-29	324	17	for	for	ADP
bptjm-29	324	18	cell	cell	NOUN
bptjm-29	324	19	-	-	PUNCT
bptjm-29	324	20	cell	cell	NOUN
bptjm-29	324	21	berkeley	berkeley	PROPN
bptjm-29	324	22	pharma	pharma	PROPN
bptjm-29	324	23	tech	tech	NOUN
bptjm-29	324	24	journal	journal	NOUN
bptjm-29	324	25	of	of	ADP
bptjm-29	324	26	medicine	medicine	NOUN
bptjm-29	324	27	|	|	ADV
bptjm-29	324	28	93	93	NUM
bptjm-29	324	29	https://www.zotero.org/google-docs/?6l8e8b	https://www.zotero.org/google-docs/?6l8e8b	PROPN
bptjm-29	324	30	https://www.zotero.org/google-docs/?xiwwfe	https://www.zotero.org/google-docs/?xiwwfe	PROPN
bptjm-29	324	31	https://www.zotero.org/google-docs/?xvmwjo	https://www.zotero.org/google-docs/?xvmwjo	PROPN
bptjm-29	324	32	https://www.zotero.org/google-docs/?sycupg	https://www.zotero.org/google-docs/?sycupg	PROPN
bptjm-29	324	33	https://www.zotero.org/google-docs/?wrre0q	https://www.zotero.org/google-docs/?wrre0q	PUNCT
bptjm-29	324	34	communication	communication	NOUN
bptjm-29	324	35	.	.	PUNCT
bptjm-29	325	1	numerous	numerous	ADJ
bptjm-29	325	2	studies	study	NOUN
bptjm-29	325	3	have	have	AUX
bptjm-29	325	4	demonstrated	demonstrate	VERB
bptjm-29	325	5	that	that	SCONJ
bptjm-29	325	6	there	there	PRON
bptjm-29	325	7	has	have	AUX
bptjm-29	325	8	been	be	AUX
bptjm-29	325	9	an	an	DET
bptjm-29	325	10	upregulation	upregulation	NOUN
bptjm-29	325	11	of	of	ADP
bptjm-29	325	12	mitochondrial	mitochondrial	ADJ
bptjm-29	325	13	respiration	respiration	NOUN
bptjm-29	325	14	and	and	CCONJ
bptjm-29	325	15	atp	atp	NOUN
bptjm-29	325	16	levels	level	NOUN
bptjm-29	325	17	with	with	ADP
bptjm-29	325	18	a	a	DET
bptjm-29	325	19	simultaneous	simultaneous	ADJ
bptjm-29	325	20	reduction	reduction	NOUN
bptjm-29	325	21	of	of	ADP
bptjm-29	325	22	oxidative	oxidative	ADJ
bptjm-29	325	23	damage	damage	NOUN
bptjm-29	325	24	upon	upon	SCONJ
bptjm-29	325	25	the	the	DET
bptjm-29	325	26	culturing	culturing	NOUN
bptjm-29	325	27	of	of	ADP
bptjm-29	325	28	mscs	msc	NOUN
bptjm-29	325	29	with	with	ADP
bptjm-29	325	30	injured	injured	ADJ
bptjm-29	325	31	tissue	tissue	NOUN
bptjm-29	325	32	,	,	PUNCT
bptjm-29	325	33	indicative	indicative	ADJ
bptjm-29	325	34	that	that	SCONJ
bptjm-29	325	35	mitochondrial	mitochondrial	ADJ
bptjm-29	325	36	transfer	transfer	NOUN
bptjm-29	325	37	is	be	AUX
bptjm-29	325	38	an	an	DET
bptjm-29	325	39	important	important	ADJ
bptjm-29	325	40	means	mean	NOUN
bptjm-29	325	41	by	by	ADP
bptjm-29	325	42	which	which	PRON
bptjm-29	325	43	cellular	cellular	ADJ
bptjm-29	325	44	functions	function	NOUN
bptjm-29	325	45	and	and	CCONJ
bptjm-29	325	46	energies	energy	NOUN
bptjm-29	325	47	can	can	AUX
bptjm-29	325	48	be	be	AUX
bptjm-29	325	49	restored	restore	VERB
bptjm-29	325	50	.	.	PUNCT
bptjm-29	326	1	there	there	PRON
bptjm-29	326	2	is	be	VERB
bptjm-29	326	3	also	also	ADV
bptjm-29	326	4	growing	grow	VERB
bptjm-29	326	5	evidence	evidence	NOUN
bptjm-29	326	6	to	to	PART
bptjm-29	326	7	suggest	suggest	VERB
bptjm-29	326	8	that	that	SCONJ
bptjm-29	326	9	mscs	msc	NOUN
bptjm-29	326	10	have	have	VERB
bptjm-29	326	11	anti	anti	ADJ
bptjm-29	326	12	-	-	ADJ
bptjm-29	326	13	apoptotic	apoptotic	ADJ
bptjm-29	326	14	e	e	NOUN
bptjm-29	326	15	�	�	NOUN
bptjm-29	326	16	ects	ect	NOUN
bptjm-29	326	17	,	,	PUNCT
bptjm-29	326	18	which	which	PRON
bptjm-29	326	19	limits	limit	VERB
bptjm-29	326	20	the	the	DET
bptjm-29	326	21	extent	extent	NOUN
bptjm-29	326	22	of	of	ADP
bptjm-29	326	23	damage	damage	NOUN
bptjm-29	326	24	to	to	PART
bptjm-29	326	25	improve	improve	VERB
bptjm-29	326	26	tissue	tissue	NOUN
bptjm-29	326	27	healing	healing	NOUN
bptjm-29	326	28	.	.	PUNCT
bptjm-29	327	1	although	although	SCONJ
bptjm-29	327	2	more	more	ADJ
bptjm-29	327	3	research	research	NOUN
bptjm-29	327	4	has	have	VERB
bptjm-29	327	5	to	to	PART
bptjm-29	327	6	be	be	AUX
bptjm-29	327	7	done	do	VERB
bptjm-29	327	8	in	in	ADP
bptjm-29	327	9	this	this	DET
bptjm-29	327	10	area	area	NOUN
bptjm-29	327	11	,	,	PUNCT
bptjm-29	327	12	exosomes	exosome	NOUN
bptjm-29	327	13	are	be	AUX
bptjm-29	327	14	used	use	VERB
bptjm-29	327	15	to	to	PART
bptjm-29	327	16	release	release	VERB
bptjm-29	327	17	factors	factor	NOUN
bptjm-29	327	18	that	that	PRON
bptjm-29	327	19	indirectly	indirectly	ADV
bptjm-29	327	20	have	have	VERB
bptjm-29	327	21	this	this	DET
bptjm-29	327	22	e	e	NOUN
bptjm-29	327	23	�	�	NOUN
bptjm-29	327	24	ect69	ect69	VERB
bptjm-29	327	25	.	.	PUNCT
bptjm-29	328	1	the	the	DET
bptjm-29	328	2	secretion	secretion	NOUN
bptjm-29	328	3	of	of	ADP
bptjm-29	328	4	exosomes	exosome	NOUN
bptjm-29	328	5	is	be	AUX
bptjm-29	328	6	an	an	DET
bptjm-29	328	7	important	important	ADJ
bptjm-29	328	8	property	property	NOUN
bptjm-29	328	9	of	of	ADP
bptjm-29	328	10	als	al	NOUN
bptjm-29	328	11	,	,	PUNCT
bptjm-29	328	12	which	which	PRON
bptjm-29	328	13	allows	allow	VERB
bptjm-29	328	14	for	for	ADP
bptjm-29	328	15	the	the	DET
bptjm-29	328	16	reduction	reduction	NOUN
bptjm-29	328	17	of	of	ADP
bptjm-29	328	18	the	the	DET
bptjm-29	328	19	e	e	PROPN
bptjm-29	328	20	�	�	PROPN
bptjm-29	328	21	ect	ect	NOUN
bptjm-29	328	22	of	of	ADP
bptjm-29	328	23	pathogenetic	pathogenetic	ADJ
bptjm-29	328	24	mechanisms	mechanism	NOUN
bptjm-29	328	25	in	in	ADP
bptjm-29	328	26	order	order	NOUN
bptjm-29	328	27	to	to	PART
bptjm-29	328	28	heal	heal	VERB
bptjm-29	328	29	damaged	damage	VERB
bptjm-29	328	30	cells	cell	NOUN
bptjm-29	328	31	.	.	PUNCT
bptjm-29	329	1	exosomes	exosome	NOUN
bptjm-29	329	2	have	have	VERB
bptjm-29	329	3	the	the	DET
bptjm-29	329	4	ability	ability	NOUN
bptjm-29	329	5	to	to	PART
bptjm-29	329	6	cross	cross	VERB
bptjm-29	329	7	the	the	DET
bptjm-29	329	8	blood	blood	NOUN
bptjm-29	329	9	-	-	PUNCT
bptjm-29	329	10	brain	brain	NOUN
bptjm-29	329	11	barrier	barrier	NOUN
bptjm-29	329	12	,	,	PUNCT
bptjm-29	329	13	which	which	PRON
bptjm-29	329	14	is	be	AUX
bptjm-29	329	15	a	a	DET
bptjm-29	329	16	unique	unique	ADJ
bptjm-29	329	17	ability	ability	NOUN
bptjm-29	329	18	and	and	CCONJ
bptjm-29	329	19	is	be	AUX
bptjm-29	329	20	signi	signi	ADJ
bptjm-29	329	21	�	�	NOUN
bptjm-29	329	22	cant	cant	NOUN
bptjm-29	329	23	for	for	ADP
bptjm-29	329	24	neurological	neurological	ADJ
bptjm-29	329	25	disorder	disorder	NOUN
bptjm-29	329	26	therapeutics	therapeutic	NOUN
bptjm-29	329	27	/	/	SYM
bptjm-29	329	28	treatment	treatment	NOUN
bptjm-29	329	29	.	.	PUNCT
bptjm-29	330	1	they	they	PRON
bptjm-29	330	2	secrete	secrete	VERB
bptjm-29	330	3	therapeutic	therapeutic	ADJ
bptjm-29	330	4	factors	factor	NOUN
bptjm-29	330	5	like	like	ADP
bptjm-29	330	6	cytokines	cytokine	NOUN
bptjm-29	330	7	that	that	PRON
bptjm-29	330	8	limit	limit	VERB
bptjm-29	330	9	in	in	ADP
bptjm-29	330	10	�	�	NOUN
bptjm-29	330	11	ammation	ammation	NOUN
bptjm-29	330	12	as	as	ADV
bptjm-29	330	13	well	well	ADV
bptjm-29	330	14	as	as	ADP
bptjm-29	330	15	trophic	trophic	ADJ
bptjm-29	330	16	factors	factor	NOUN
bptjm-29	330	17	that	that	PRON
bptjm-29	330	18	help	help	AUX
bptjm-29	330	19	maintain	maintain	VERB
bptjm-29	330	20	brain	brain	NOUN
bptjm-29	330	21	and	and	CCONJ
bptjm-29	330	22	spinal	spinal	ADJ
bptjm-29	330	23	cord	cord	NOUN
bptjm-29	330	24	connectivity	connectivity	NOUN
bptjm-29	330	25	to	to	ADP
bptjm-29	330	26	muscle	muscle	NOUN
bptjm-29	330	27	cells	cell	NOUN
bptjm-29	330	28	.	.	PUNCT
bptjm-29	331	1	additionally	additionally	ADV
bptjm-29	331	2	,	,	PUNCT
bptjm-29	331	3	studies	study	NOUN
bptjm-29	331	4	have	have	AUX
bptjm-29	331	5	shown	show	VERB
bptjm-29	331	6	that	that	SCONJ
bptjm-29	331	7	msc	msc	PROPN
bptjm-29	331	8	derived	derive	VERB
bptjm-29	331	9	exosomes	exosome	NOUN
bptjm-29	331	10	mediate	mediate	VERB
bptjm-29	331	11	angiogenesis8	angiogenesis8	PROPN
bptjm-29	331	12	,	,	PUNCT
bptjm-29	331	13	and	and	CCONJ
bptjm-29	331	14	this	this	DET
bptjm-29	331	15	enhancement	enhancement	NOUN
bptjm-29	331	16	of	of	ADP
bptjm-29	331	17	angiogenesis	angiogenesis	NOUN
bptjm-29	331	18	and	and	CCONJ
bptjm-29	331	19	myogenesis	myogenesis	NOUN
bptjm-29	331	20	promotes	promote	VERB
bptjm-29	331	21	muscle	muscle	NOUN
bptjm-29	331	22	regeneration	regeneration	NOUN
bptjm-29	331	23	,	,	PUNCT
bptjm-29	331	24	which	which	PRON
bptjm-29	331	25	is	be	AUX
bptjm-29	331	26	crucial	crucial	ADJ
bptjm-29	331	27	for	for	ADP
bptjm-29	331	28	als	als	NOUN
bptjm-29	331	29	treatment	treatment	NOUN
bptjm-29	331	30	in	in	ADP
bptjm-29	331	31	which	which	PRON
bptjm-29	331	32	the	the	DET
bptjm-29	331	33	motor	motor	NOUN
bptjm-29	331	34	neurons	neuron	NOUN
bptjm-29	331	35	are	be	AUX
bptjm-29	331	36	implicated	implicate	VERB
bptjm-29	331	37	.	.	PUNCT
bptjm-29	332	1	studies	study	NOUN
bptjm-29	332	2	have	have	AUX
bptjm-29	332	3	indicated	indicate	VERB
bptjm-29	332	4	that	that	SCONJ
bptjm-29	332	5	mscs	msc	NOUN
bptjm-29	332	6	have	have	AUX
bptjm-29	332	7	successfully	successfully	ADV
bptjm-29	332	8	improved	improve	VERB
bptjm-29	332	9	the	the	DET
bptjm-29	332	10	pathological	pathological	ADJ
bptjm-29	332	11	features	feature	NOUN
bptjm-29	332	12	and	and	CCONJ
bptjm-29	332	13	development	development	NOUN
bptjm-29	332	14	of	of	ADP
bptjm-29	332	15	als	al	NOUN
bptjm-29	332	16	and	and	CCONJ
bptjm-29	332	17	display	display	VERB
bptjm-29	332	18	a	a	DET
bptjm-29	332	19	high	high	ADJ
bptjm-29	332	20	level	level	NOUN
bptjm-29	332	21	of	of	ADP
bptjm-29	332	22	therapeutic	therapeutic	ADJ
bptjm-29	332	23	plasticity7	plasticity7	NOUN
bptjm-29	332	24	.	.	PUNCT
bptjm-29	333	1	therefore	therefore	ADV
bptjm-29	333	2	,	,	PUNCT
bptjm-29	333	3	mscs	msc	NOUN
bptjm-29	333	4	would	would	AUX
bptjm-29	333	5	be	be	AUX
bptjm-29	333	6	a	a	DET
bptjm-29	333	7	promising	promising	ADJ
bptjm-29	333	8	cure	cure	NOUN
bptjm-29	333	9	as	as	SCONJ
bptjm-29	333	10	it	it	PRON
bptjm-29	333	11	allows	allow	VERB
bptjm-29	333	12	for	for	SCONJ
bptjm-29	333	13	di	di	NOUN
bptjm-29	333	14	�	�	PROPN
bptjm-29	333	15	erentiated	erentiate	VERB
bptjm-29	333	16	motor	motor	NOUN
bptjm-29	333	17	neurons	neuron	NOUN
bptjm-29	333	18	to	to	PART
bptjm-29	333	19	replace	replace	VERB
bptjm-29	333	20	damaged	damaged	ADJ
bptjm-29	333	21	cells	cell	NOUN
bptjm-29	333	22	while	while	SCONJ
bptjm-29	333	23	also	also	ADV
bptjm-29	333	24	providing	provide	VERB
bptjm-29	333	25	mechanisms	mechanism	NOUN
bptjm-29	333	26	for	for	ADP
bptjm-29	333	27	the	the	DET
bptjm-29	333	28	damaged	damage	VERB
bptjm-29	333	29	cells	cell	NOUN
bptjm-29	333	30	to	to	PART
bptjm-29	333	31	repair	repair	VERB
bptjm-29	333	32	themselves	themselves	PRON
bptjm-29	333	33	.	.	PUNCT
bptjm-29	334	1	8	8	X
bptjm-29	334	2	.	.	PUNCT
bptjm-29	334	3	practical	practical	ADJ
bptjm-29	334	4	applications	application	NOUN
bptjm-29	334	5	there	there	PRON
bptjm-29	334	6	have	have	AUX
bptjm-29	334	7	been	be	AUX
bptjm-29	334	8	numerous	numerous	ADJ
bptjm-29	334	9	studies	study	NOUN
bptjm-29	334	10	conducted	conduct	VERB
bptjm-29	334	11	regarding	regard	VERB
bptjm-29	334	12	mscs	msc	NOUN
bptjm-29	334	13	and	and	CCONJ
bptjm-29	334	14	their	their	PRON
bptjm-29	334	15	applications	application	NOUN
bptjm-29	334	16	as	as	ADP
bptjm-29	334	17	a	a	DET
bptjm-29	334	18	therapeutic	therapeutic	NOUN
bptjm-29	334	19	for	for	ADP
bptjm-29	334	20	als	al	NOUN
bptjm-29	334	21	,	,	PUNCT
bptjm-29	334	22	many	many	ADJ
bptjm-29	334	23	of	of	ADP
bptjm-29	334	24	which	which	PRON
bptjm-29	334	25	have	have	AUX
bptjm-29	334	26	o	o	NOUN
bptjm-29	334	27	�	�	PROPN
bptjm-29	334	28	ered	ere	VERB
bptjm-29	334	29	a	a	DET
bptjm-29	334	30	greater	great	ADJ
bptjm-29	334	31	insight	insight	NOUN
bptjm-29	334	32	into	into	ADP
bptjm-29	334	33	potential	potential	ADJ
bptjm-29	334	34	applications	application	NOUN
bptjm-29	334	35	of	of	ADP
bptjm-29	334	36	mscs	msc	NOUN
bptjm-29	334	37	in	in	ADP
bptjm-29	334	38	a	a	DET
bptjm-29	334	39	clinical	clinical	ADJ
bptjm-29	334	40	setting	setting	NOUN
bptjm-29	334	41	.	.	PUNCT
bptjm-29	335	1	clinical	clinical	ADJ
bptjm-29	335	2	trials	trial	NOUN
bptjm-29	335	3	have	have	AUX
bptjm-29	335	4	indicated	indicate	VERB
bptjm-29	335	5	that	that	SCONJ
bptjm-29	335	6	msc	msc	PROPN
bptjm-29	335	7	cells	cell	NOUN
bptjm-29	335	8	,	,	PUNCT
bptjm-29	335	9	upon	upon	SCONJ
bptjm-29	335	10	their	their	PRON
bptjm-29	335	11	transplantation	transplantation	NOUN
bptjm-29	335	12	,	,	PUNCT
bptjm-29	335	13	are	be	AUX
bptjm-29	335	14	capable	capable	ADJ
bptjm-29	335	15	of	of	ADP
bptjm-29	335	16	inducing	induce	VERB
bptjm-29	335	17	a	a	DET
bptjm-29	335	18	substantial	substantial	ADJ
bptjm-29	335	19	upregulation	upregulation	NOUN
bptjm-29	335	20	of	of	ADP
bptjm-29	335	21	neurotrophic	neurotrophic	ADJ
bptjm-29	335	22	factors	factor	NOUN
bptjm-29	335	23	,	,	PUNCT
bptjm-29	335	24	some	some	PRON
bptjm-29	335	25	of	of	ADP
bptjm-29	335	26	which	which	PRON
bptjm-29	335	27	include	include	VERB
bptjm-29	335	28	the	the	DET
bptjm-29	335	29	glial	glial	ADJ
bptjm-29	335	30	-	-	PUNCT
bptjm-29	335	31	derived	derive	VERB
bptjm-29	335	32	neurotrophic	neurotrophic	ADJ
bptjm-29	335	33	factor	factor	NOUN
bptjm-29	335	34	and	and	CCONJ
bptjm-29	335	35	the	the	DET
bptjm-29	335	36	basic	basic	ADJ
bptjm-29	335	37	�	�	PROPN
bptjm-29	335	38	broblast	broblast	ADJ
bptjm-29	335	39	growth	growth	NOUN
bptjm-29	335	40	factor	factor	NOUN
bptjm-29	335	41	.	.	PUNCT
bptjm-29	336	1	neurotrophic	neurotrophic	ADJ
bptjm-29	336	2	factors	factor	NOUN
bptjm-29	336	3	are	be	AUX
bptjm-29	336	4	crucial	crucial	ADJ
bptjm-29	336	5	with	with	ADP
bptjm-29	336	6	respect	respect	NOUN
bptjm-29	336	7	to	to	ADP
bptjm-29	336	8	the	the	DET
bptjm-29	336	9	consideration	consideration	NOUN
bptjm-29	336	10	of	of	ADP
bptjm-29	336	11	potential	potential	ADJ
bptjm-29	336	12	treatments	treatment	NOUN
bptjm-29	336	13	for	for	ADP
bptjm-29	336	14	als	al	NOUN
bptjm-29	336	15	,	,	PUNCT
bptjm-29	336	16	since	since	SCONJ
bptjm-29	336	17	it	it	PRON
bptjm-29	336	18	has	have	AUX
bptjm-29	336	19	been	be	AUX
bptjm-29	336	20	berkeley	berkeley	PROPN
bptjm-29	336	21	pharma	pharma	PROPN
bptjm-29	336	22	tech	tech	NOUN
bptjm-29	336	23	journal	journal	NOUN
bptjm-29	336	24	of	of	ADP
bptjm-29	336	25	medicine	medicine	NOUN
bptjm-29	337	1	|	|	ADV
bptjm-29	337	2	94	94	NUM
bptjm-29	337	3	https://www.zotero.org/google-docs/?vvsgzt	https://www.zotero.org/google-docs/?vvsgzt	NOUN
bptjm-29	337	4	https://www.zotero.org/google-docs/?m5mjza	https://www.zotero.org/google-docs/?m5mjza	PROPN
bptjm-29	337	5	https://www.zotero.org/google-docs/?inkv8k	https://www.zotero.org/google-docs/?inkv8k	PROPN
bptjm-29	337	6	demonstrated	demonstrate	VERB
bptjm-29	337	7	that	that	SCONJ
bptjm-29	337	8	they	they	PRON
bptjm-29	337	9	prolong	prolong	VERB
bptjm-29	337	10	motor	motor	PROPN
bptjm-29	337	11	neuron	neuron	PROPN
bptjm-29	337	12	survival	survival	PROPN
bptjm-29	337	13	in	in	ADP
bptjm-29	337	14	als	als	NOUN
bptjm-29	337	15	.	.	PUNCT
bptjm-29	338	1	a	a	DET
bptjm-29	338	2	uni	uni	PROPN
bptjm-29	338	3	�	�	PROPN
bptjm-29	338	4	ed	ed	NOUN
bptjm-29	338	5	delivery	delivery	NOUN
bptjm-29	338	6	of	of	ADP
bptjm-29	338	7	various	various	ADJ
bptjm-29	338	8	neurotrophic	neurotrophic	ADJ
bptjm-29	338	9	factors	factor	NOUN
bptjm-29	338	10	has	have	AUX
bptjm-29	338	11	been	be	AUX
bptjm-29	338	12	shown	show	VERB
bptjm-29	338	13	to	to	PART
bptjm-29	338	14	have	have	VERB
bptjm-29	338	15	a	a	DET
bptjm-29	338	16	synergistic	synergistic	ADJ
bptjm-29	338	17	e	e	NOUN
bptjm-29	338	18	�	�	NOUN
bptjm-29	338	19	ect	ect	VERB
bptjm-29	338	20	on	on	ADP
bptjm-29	338	21	the	the	DET
bptjm-29	338	22	pathogenesis	pathogenesis	NOUN
bptjm-29	338	23	of	of	ADP
bptjm-29	338	24	als	als	NOUN
bptjm-29	338	25	itself	itself	PRON
bptjm-29	338	26	,	,	PUNCT
bptjm-29	338	27	and	and	CCONJ
bptjm-29	338	28	mscs	msc	NOUN
bptjm-29	338	29	induced	induce	VERB
bptjm-29	338	30	with	with	ADP
bptjm-29	338	31	neurotrophic	neurotrophic	ADJ
bptjm-29	338	32	growth	growth	NOUN
bptjm-29	338	33	factors	factor	NOUN
bptjm-29	338	34	are	be	AUX
bptjm-29	338	35	demonstrated	demonstrate	VERB
bptjm-29	338	36	to	to	PART
bptjm-29	338	37	display	display	VERB
bptjm-29	338	38	protective	protective	ADJ
bptjm-29	338	39	e	e	NOUN
bptjm-29	338	40	�	�	NOUN
bptjm-29	338	41	ects	ect	VERB
bptjm-29	338	42	in	in	ADP
bptjm-29	338	43	many	many	ADJ
bptjm-29	338	44	neurodegenerative	neurodegenerative	ADJ
bptjm-29	338	45	disease	disease	NOUN
bptjm-29	338	46	models71	models71	NOUN
bptjm-29	338	47	.	.	PUNCT
bptjm-29	339	1	in	in	ADP
bptjm-29	339	2	a	a	DET
bptjm-29	339	3	similar	similar	ADJ
bptjm-29	339	4	clinical	clinical	ADJ
bptjm-29	339	5	trial	trial	NOUN
bptjm-29	339	6	,	,	PUNCT
bptjm-29	339	7	a	a	DET
bptjm-29	339	8	medium	medium	NOUN
bptjm-29	339	9	based	base	VERB
bptjm-29	339	10	msc	msc	PROPN
bptjm-29	339	11	induction	induction	NOUN
bptjm-29	339	12	process	process	NOUN
bptjm-29	339	13	was	be	AUX
bptjm-29	339	14	devised	devise	VERB
bptjm-29	339	15	in	in	ADP
bptjm-29	339	16	which	which	PRON
bptjm-29	339	17	mscs	msc	NOUN
bptjm-29	339	18	were	be	AUX
bptjm-29	339	19	induced	induce	VERB
bptjm-29	339	20	with	with	ADP
bptjm-29	339	21	neurotrophic	neurotrophic	ADJ
bptjm-29	339	22	factors	factor	NOUN
bptjm-29	339	23	,	,	PUNCT
bptjm-29	339	24	which	which	PRON
bptjm-29	339	25	possessed	possess	VERB
bptjm-29	339	26	the	the	DET
bptjm-29	339	27	ability	ability	NOUN
bptjm-29	339	28	of	of	ADP
bptjm-29	339	29	an	an	DET
bptjm-29	339	30	enhanced	enhanced	ADJ
bptjm-29	339	31	secretion	secretion	NOUN
bptjm-29	339	32	of	of	ADP
bptjm-29	339	33	gdnf	gdnf	PROPN
bptjm-29	339	34	,	,	PUNCT
bptjm-29	339	35	vegf	vegf	PROPN
bptjm-29	339	36	(	(	PUNCT
bptjm-29	339	37	vascular	vascular	ADJ
bptjm-29	339	38	endothelial	endothelial	ADJ
bptjm-29	339	39	growth	growth	NOUN
bptjm-29	339	40	factor	factor	NOUN
bptjm-29	339	41	)	)	PUNCT
bptjm-29	339	42	,	,	PUNCT
bptjm-29	339	43	the	the	DET
bptjm-29	339	44	hepatocyte	hepatocyte	NOUN
bptjm-29	339	45	growth	growth	NOUN
bptjm-29	339	46	factor	factor	NOUN
bptjm-29	339	47	,	,	PUNCT
bptjm-29	339	48	and	and	CCONJ
bptjm-29	339	49	brain	brain	NOUN
bptjm-29	339	50	-	-	PUNCT
bptjm-29	339	51	derived	derive	VERB
bptjm-29	339	52	neurotrophic	neurotrophic	ADJ
bptjm-29	339	53	factors71	factors71	NOUN
bptjm-29	339	54	.	.	PUNCT
bptjm-29	340	1	upon	upon	SCONJ
bptjm-29	340	2	the	the	DET
bptjm-29	340	3	transplantation	transplantation	NOUN
bptjm-29	340	4	of	of	ADP
bptjm-29	340	5	these	these	DET
bptjm-29	340	6	neurotrophic	neurotrophic	ADJ
bptjm-29	340	7	factor	factor	NOUN
bptjm-29	340	8	induced	induce	VERB
bptjm-29	340	9	mscs	msc	NOUN
bptjm-29	340	10	,	,	PUNCT
bptjm-29	340	11	no	no	DET
bptjm-29	340	12	signi	signi	PROPN
bptjm-29	340	13	�	�	NOUN
bptjm-29	340	14	cant	cant	VERB
bptjm-29	340	15	adverse	adverse	ADJ
bptjm-29	340	16	e	e	NOUN
bptjm-29	340	17	�	�	NOUN
bptjm-29	340	18	ects	ect	NOUN
bptjm-29	340	19	were	be	AUX
bptjm-29	340	20	noted	note	VERB
bptjm-29	340	21	,	,	PUNCT
bptjm-29	340	22	and	and	CCONJ
bptjm-29	340	23	a	a	DET
bptjm-29	340	24	higher	high	ADJ
bptjm-29	340	25	secretion	secretion	NOUN
bptjm-29	340	26	of	of	ADP
bptjm-29	340	27	neurotrophic	neurotrophic	ADJ
bptjm-29	340	28	factors	factor	NOUN
bptjm-29	340	29	was	be	AUX
bptjm-29	340	30	observed	observe	VERB
bptjm-29	340	31	,	,	PUNCT
bptjm-29	340	32	which	which	PRON
bptjm-29	340	33	directly	directly	ADV
bptjm-29	340	34	correlated	correlate	VERB
bptjm-29	340	35	with	with	ADP
bptjm-29	340	36	a	a	DET
bptjm-29	340	37	substantial	substantial	ADJ
bptjm-29	340	38	improvement	improvement	NOUN
bptjm-29	340	39	in	in	ADP
bptjm-29	340	40	the	the	DET
bptjm-29	340	41	monthly	monthly	ADJ
bptjm-29	340	42	rate	rate	NOUN
bptjm-29	340	43	of	of	ADP
bptjm-29	340	44	decline	decline	NOUN
bptjm-29	340	45	of	of	ADP
bptjm-29	340	46	als	als	NOUN
bptjm-29	340	47	pathogenesis	pathogenesis	NOUN
bptjm-29	340	48	.	.	PUNCT
bptjm-29	341	1	similarly	similarly	ADV
bptjm-29	341	2	,	,	PUNCT
bptjm-29	341	3	it	it	PRON
bptjm-29	341	4	has	have	AUX
bptjm-29	341	5	been	be	AUX
bptjm-29	341	6	found	find	VERB
bptjm-29	341	7	that	that	SCONJ
bptjm-29	341	8	when	when	SCONJ
bptjm-29	341	9	mscs	msc	NOUN
bptjm-29	341	10	have	have	AUX
bptjm-29	341	11	been	be	AUX
bptjm-29	341	12	cocultured	coculture	VERB
bptjm-29	341	13	with	with	ADP
bptjm-29	341	14	healthy	healthy	ADJ
bptjm-29	341	15	tissues	tissue	NOUN
bptjm-29	341	16	,	,	PUNCT
bptjm-29	341	17	there	there	PRON
bptjm-29	341	18	is	be	VERB
bptjm-29	341	19	a	a	DET
bptjm-29	341	20	reduction	reduction	NOUN
bptjm-29	341	21	in	in	ADP
bptjm-29	341	22	oxidative	oxidative	ADJ
bptjm-29	341	23	damage	damage	NOUN
bptjm-29	341	24	,	,	PUNCT
bptjm-29	341	25	an	an	DET
bptjm-29	341	26	upregulation	upregulation	NOUN
bptjm-29	341	27	of	of	ADP
bptjm-29	341	28	mitochondrial	mitochondrial	ADJ
bptjm-29	341	29	respiration	respiration	NOUN
bptjm-29	341	30	(	(	PUNCT
bptjm-29	341	31	indicative	indicative	ADJ
bptjm-29	341	32	of	of	ADP
bptjm-29	341	33	proper	proper	ADJ
bptjm-29	341	34	cellular	cellular	ADJ
bptjm-29	341	35	function	function	NOUN
bptjm-29	341	36	and	and	CCONJ
bptjm-29	341	37	mitochondrial	mitochondrial	ADJ
bptjm-29	341	38	transfer	transfer	NOUN
bptjm-29	341	39	)	)	PUNCT
bptjm-29	341	40	,	,	PUNCT
bptjm-29	341	41	and	and	CCONJ
bptjm-29	341	42	an	an	DET
bptjm-29	341	43	upregulation	upregulation	NOUN
bptjm-29	341	44	of	of	ADP
bptjm-29	341	45	atp	atp	PROPN
bptjm-29	341	46	levels70	levels70	PROPN
bptjm-29	341	47	.	.	PUNCT
bptjm-29	342	1	in	in	ADP
bptjm-29	342	2	general	general	ADJ
bptjm-29	342	3	,	,	PUNCT
bptjm-29	342	4	though	though	ADV
bptjm-29	342	5	,	,	PUNCT
bptjm-29	342	6	the	the	DET
bptjm-29	342	7	practical	practical	ADJ
bptjm-29	342	8	and	and	CCONJ
bptjm-29	342	9	clinical	clinical	ADJ
bptjm-29	342	10	applications	application	NOUN
bptjm-29	342	11	of	of	ADP
bptjm-29	342	12	mscs	msc	NOUN
bptjm-29	342	13	are	be	AUX
bptjm-29	342	14	attributed	attribute	VERB
bptjm-29	342	15	to	to	ADP
bptjm-29	342	16	their	their	PRON
bptjm-29	342	17	di	di	NOUN
bptjm-29	342	18	�	�	PROPN
bptjm-29	342	19	erentiation	erentiation	NOUN
bptjm-29	342	20	plasticity	plasticity	NOUN
bptjm-29	342	21	,	,	PUNCT
bptjm-29	342	22	their	their	PRON
bptjm-29	342	23	capability	capability	NOUN
bptjm-29	342	24	of	of	ADP
bptjm-29	342	25	the	the	DET
bptjm-29	342	26	secretion	secretion	NOUN
bptjm-29	342	27	of	of	ADP
bptjm-29	342	28	bioactive	bioactive	ADJ
bptjm-29	342	29	compounds	compound	NOUN
bptjm-29	342	30	as	as	ADV
bptjm-29	342	31	dependent	dependent	ADJ
bptjm-29	342	32	on	on	ADP
bptjm-29	342	33	the	the	DET
bptjm-29	342	34	microenvironmental	microenvironmental	ADJ
bptjm-29	342	35	condition	condition	NOUN
bptjm-29	342	36	(	(	PUNCT
bptjm-29	342	37	playing	play	VERB
bptjm-29	342	38	a	a	DET
bptjm-29	342	39	role	role	NOUN
bptjm-29	342	40	in	in	ADP
bptjm-29	342	41	immunomodulation	immunomodulation	NOUN
bptjm-29	342	42	,	,	PUNCT
bptjm-29	342	43	reduction	reduction	NOUN
bptjm-29	342	44	of	of	ADP
bptjm-29	342	45	in	in	ADP
bptjm-29	342	46	�	�	PROPN
bptjm-29	342	47	ammation	ammation	NOUN
bptjm-29	342	48	,	,	PUNCT
bptjm-29	342	49	and	and	CCONJ
bptjm-29	342	50	regeneration	regeneration	NOUN
bptjm-29	342	51	)	)	PUNCT
bptjm-29	342	52	,	,	PUNCT
bptjm-29	342	53	their	their	PRON
bptjm-29	342	54	ability	ability	NOUN
bptjm-29	342	55	to	to	PART
bptjm-29	342	56	migrate	migrate	VERB
bptjm-29	342	57	to	to	ADP
bptjm-29	342	58	sites	site	NOUN
bptjm-29	342	59	of	of	ADP
bptjm-29	342	60	injured	injure	VERB
bptjm-29	342	61	tissue	tissue	NOUN
bptjm-29	342	62	upon	upon	SCONJ
bptjm-29	342	63	intravenous	intravenous	ADJ
bptjm-29	342	64	injection	injection	NOUN
bptjm-29	342	65	,	,	PUNCT
bptjm-29	342	66	and	and	CCONJ
bptjm-29	342	67	their	their	PRON
bptjm-29	342	68	immunomodulatory	immunomodulatory	ADJ
bptjm-29	342	69	capacities72	capacities72	NOUN
bptjm-29	342	70	.	.	PUNCT
bptjm-29	343	1	9	9	X
bptjm-29	343	2	.	.	X
bptjm-29	343	3	future	future	ADJ
bptjm-29	343	4	directions	direction	NOUN
bptjm-29	343	5	mscs	msc	NOUN
bptjm-29	343	6	do	do	AUX
bptjm-29	343	7	present	present	VERB
bptjm-29	343	8	a	a	DET
bptjm-29	343	9	few	few	ADJ
bptjm-29	343	10	challenges	challenge	NOUN
bptjm-29	343	11	with	with	ADP
bptjm-29	343	12	regard	regard	NOUN
bptjm-29	343	13	to	to	ADP
bptjm-29	343	14	their	their	PRON
bptjm-29	343	15	transplantation	transplantation	NOUN
bptjm-29	343	16	and	and	CCONJ
bptjm-29	343	17	application	application	NOUN
bptjm-29	343	18	as	as	ADP
bptjm-29	343	19	a	a	DET
bptjm-29	343	20	reliable	reliable	ADJ
bptjm-29	343	21	disease	disease	NOUN
bptjm-29	343	22	therapeutic	therapeutic	ADJ
bptjm-29	343	23	that	that	PRON
bptjm-29	343	24	need	need	VERB
bptjm-29	343	25	to	to	PART
bptjm-29	343	26	be	be	AUX
bptjm-29	343	27	further	far	ADV
bptjm-29	343	28	researched	research	VERB
bptjm-29	343	29	before	before	ADP
bptjm-29	343	30	use	use	NOUN
bptjm-29	343	31	.	.	PUNCT
bptjm-29	344	1	for	for	ADP
bptjm-29	344	2	example	example	NOUN
bptjm-29	344	3	,	,	PUNCT
bptjm-29	344	4	challenges	challenge	NOUN
bptjm-29	344	5	can	can	AUX
bptjm-29	344	6	arise	arise	VERB
bptjm-29	344	7	in	in	ADP
bptjm-29	344	8	the	the	DET
bptjm-29	344	9	characterization	characterization	NOUN
bptjm-29	344	10	of	of	ADP
bptjm-29	344	11	mscs	msc	NOUN
bptjm-29	344	12	,	,	PUNCT
bptjm-29	344	13	because	because	SCONJ
bptjm-29	344	14	after	after	SCONJ
bptjm-29	344	15	they	they	PRON
bptjm-29	344	16	are	be	AUX
bptjm-29	344	17	isolated	isolate	VERB
bptjm-29	344	18	and	and	CCONJ
bptjm-29	344	19	selected	select	VERB
bptjm-29	344	20	,	,	PUNCT
bptjm-29	344	21	it	it	PRON
bptjm-29	344	22	must	must	AUX
bptjm-29	344	23	be	be	AUX
bptjm-29	344	24	ensured	ensure	VERB
bptjm-29	344	25	that	that	SCONJ
bptjm-29	344	26	the	the	DET
bptjm-29	344	27	mscs	msc	NOUN
bptjm-29	344	28	are	be	AUX
bptjm-29	344	29	pure	pure	ADJ
bptjm-29	344	30	,	,	PUNCT
bptjm-29	344	31	active	active	ADJ
bptjm-29	344	32	,	,	PUNCT
bptjm-29	344	33	undi	undi	PROPN
bptjm-29	344	34	�	�	PROPN
bptjm-29	344	35	erentiated	erentiate	VERB
bptjm-29	344	36	,	,	PUNCT
bptjm-29	344	37	and	and	CCONJ
bptjm-29	344	38	functional	functional	ADJ
bptjm-29	344	39	for	for	ADP
bptjm-29	344	40	their	their	PRON
bptjm-29	344	41	clinical	clinical	ADJ
bptjm-29	344	42	application	application	NOUN
bptjm-29	344	43	.	.	PUNCT
bptjm-29	345	1	in	in	ADP
bptjm-29	345	2	addition	addition	NOUN
bptjm-29	345	3	,	,	PUNCT
bptjm-29	345	4	when	when	SCONJ
bptjm-29	345	5	mscs	msc	NOUN
bptjm-29	345	6	are	be	AUX
bptjm-29	345	7	utilized	utilize	VERB
bptjm-29	345	8	in	in	ADP
bptjm-29	345	9	cell	cell	NOUN
bptjm-29	345	10	delivery	delivery	NOUN
bptjm-29	345	11	treatments	treatment	NOUN
bptjm-29	345	12	such	such	ADJ
bptjm-29	345	13	as	as	ADP
bptjm-29	345	14	in	in	ADP
bptjm-29	345	15	neurodegenerative	neurodegenerative	ADJ
bptjm-29	345	16	disorders	disorder	NOUN
bptjm-29	345	17	,	,	PUNCT
bptjm-29	345	18	it	it	PRON
bptjm-29	345	19	must	must	AUX
bptjm-29	345	20	be	be	AUX
bptjm-29	345	21	ensured	ensure	VERB
bptjm-29	345	22	that	that	SCONJ
bptjm-29	345	23	the	the	DET
bptjm-29	345	24	microenvironment	microenvironment	NOUN
bptjm-29	345	25	of	of	ADP
bptjm-29	345	26	the	the	DET
bptjm-29	345	27	host	host	NOUN
bptjm-29	345	28	meets	meet	VERB
bptjm-29	345	29	the	the	DET
bptjm-29	345	30	requirements	requirement	NOUN
bptjm-29	345	31	of	of	ADP
bptjm-29	345	32	the	the	DET
bptjm-29	345	33	speci	speci	PROPN
bptjm-29	345	34	�	�	PROPN
bptjm-29	345	35	c	c	PROPN
bptjm-29	345	36	type	type	NOUN
bptjm-29	345	37	of	of	ADP
bptjm-29	345	38	cell56	cell56	NOUN
bptjm-29	345	39	.	.	PUNCT
bptjm-29	346	1	also	also	ADV
bptjm-29	346	2	,	,	PUNCT
bptjm-29	346	3	although	although	SCONJ
bptjm-29	346	4	msc	msc	PROPN
bptjm-29	346	5	therapies	therapy	NOUN
bptjm-29	346	6	are	be	AUX
bptjm-29	346	7	berkeley	berkeley	PROPN
bptjm-29	346	8	pharma	pharma	PROPN
bptjm-29	346	9	tech	tech	NOUN
bptjm-29	346	10	journal	journal	NOUN
bptjm-29	346	11	of	of	ADP
bptjm-29	346	12	medicine	medicine	NOUN
bptjm-29	346	13	|	|	ADV
bptjm-29	346	14	95	95	NUM
bptjm-29	346	15	https://www.zotero.org/google-docs/?nsak57	https://www.zotero.org/google-docs/?nsak57	NOUN
bptjm-29	346	16	https://www.zotero.org/google-docs/?myofjo	https://www.zotero.org/google-docs/?myofjo	PROPN
bptjm-29	346	17	https://www.zotero.org/google-docs/?8lidxr	https://www.zotero.org/google-docs/?8lidxr	PROPN
bptjm-29	346	18	https://www.zotero.org/google-docs/?yinhrb	https://www.zotero.org/google-docs/?yinhrb	PROPN
bptjm-29	346	19	https://www.zotero.org/google-docs/?bgmoyd	https://www.zotero.org/google-docs/?bgmoyd	PROPN
bptjm-29	346	20	generally	generally	ADV
bptjm-29	346	21	considered	consider	VERB
bptjm-29	346	22	to	to	PART
bptjm-29	346	23	be	be	AUX
bptjm-29	346	24	safe	safe	ADJ
bptjm-29	346	25	as	as	SCONJ
bptjm-29	346	26	documented	document	VERB
bptjm-29	346	27	in	in	ADP
bptjm-29	346	28	various	various	ADJ
bptjm-29	346	29	clinical	clinical	ADJ
bptjm-29	346	30	studies	study	NOUN
bptjm-29	346	31	,	,	PUNCT
bptjm-29	346	32	the	the	DET
bptjm-29	346	33	utilization	utilization	NOUN
bptjm-29	346	34	of	of	ADP
bptjm-29	346	35	a	a	DET
bptjm-29	346	36	relatively	relatively	ADV
bptjm-29	346	37	large	large	ADJ
bptjm-29	346	38	number	number	NOUN
bptjm-29	346	39	of	of	ADP
bptjm-29	346	40	living	live	VERB
bptjm-29	346	41	mscs	msc	NOUN
bptjm-29	346	42	carries	carry	VERB
bptjm-29	346	43	certain	certain	ADJ
bptjm-29	346	44	risks	risk	NOUN
bptjm-29	346	45	,	,	PUNCT
bptjm-29	346	46	such	such	ADJ
bptjm-29	346	47	as	as	ADP
bptjm-29	346	48	occlusion	occlusion	NOUN
bptjm-29	346	49	within	within	ADP
bptjm-29	346	50	arterioles	arteriole	NOUN
bptjm-29	346	51	,	,	PUNCT
bptjm-29	346	52	capillaries	capillary	NOUN
bptjm-29	346	53	,	,	PUNCT
bptjm-29	346	54	and	and	CCONJ
bptjm-29	346	55	venules	venule	NOUN
bptjm-29	346	56	,	,	PUNCT
bptjm-29	346	57	a	a	DET
bptjm-29	346	58	transformation	transformation	NOUN
bptjm-29	346	59	of	of	ADP
bptjm-29	346	60	transplanted	transplanted	ADJ
bptjm-29	346	61	cells	cell	NOUN
bptjm-29	346	62	into	into	ADP
bptjm-29	346	63	inappropriate	inappropriate	ADJ
bptjm-29	346	64	cell	cell	NOUN
bptjm-29	346	65	types	type	NOUN
bptjm-29	346	66	such	such	ADJ
bptjm-29	346	67	as	as	ADP
bptjm-29	346	68	those	those	PRON
bptjm-29	346	69	displaying	display	VERB
bptjm-29	346	70	malignancies	malignancy	NOUN
bptjm-29	346	71	,	,	PUNCT
bptjm-29	346	72	and	and	CCONJ
bptjm-29	346	73	proarrhythmia	proarrhythmia	NOUN
bptjm-29	346	74	.	.	PUNCT
bptjm-29	347	1	similarly	similarly	ADV
bptjm-29	347	2	,	,	PUNCT
bptjm-29	347	3	the	the	DET
bptjm-29	347	4	transplantation	transplantation	NOUN
bptjm-29	347	5	of	of	ADP
bptjm-29	347	6	living	living	NOUN
bptjm-29	347	7	cells	cell	NOUN
bptjm-29	347	8	with	with	ADP
bptjm-29	347	9	the	the	DET
bptjm-29	347	10	ability	ability	NOUN
bptjm-29	347	11	to	to	PART
bptjm-29	347	12	replicate	replicate	VERB
bptjm-29	347	13	is	be	AUX
bptjm-29	347	14	inherently	inherently	ADV
bptjm-29	347	15	high	high	ADJ
bptjm-29	347	16	-	-	PUNCT
bptjm-29	347	17	risk	risk	NOUN
bptjm-29	347	18	,	,	PUNCT
bptjm-29	347	19	because	because	SCONJ
bptjm-29	347	20	the	the	DET
bptjm-29	347	21	grafted	grafted	ADJ
bptjm-29	347	22	cells	cell	NOUN
bptjm-29	347	23	can	can	AUX
bptjm-29	347	24	not	not	PART
bptjm-29	347	25	be	be	AUX
bptjm-29	347	26	completely	completely	ADV
bptjm-29	347	27	removed	remove	VERB
bptjm-29	347	28	if	if	SCONJ
bptjm-29	347	29	there	there	PRON
bptjm-29	347	30	is	be	VERB
bptjm-29	347	31	an	an	DET
bptjm-29	347	32	adverse	adverse	ADJ
bptjm-29	347	33	response	response	NOUN
bptjm-29	347	34	to	to	ADP
bptjm-29	347	35	treatment	treatment	NOUN
bptjm-29	347	36	or	or	CCONJ
bptjm-29	347	37	if	if	SCONJ
bptjm-29	347	38	the	the	DET
bptjm-29	347	39	disease	disease	NOUN
bptjm-29	347	40	is	be	AUX
bptjm-29	347	41	ultimately	ultimately	ADV
bptjm-29	347	42	resolved59	resolved59	ADJ
bptjm-29	347	43	.	.	PUNCT
bptjm-29	348	1	moreover	moreover	ADV
bptjm-29	348	2	,	,	PUNCT
bptjm-29	348	3	it	it	PRON
bptjm-29	348	4	has	have	AUX
bptjm-29	348	5	been	be	AUX
bptjm-29	348	6	demonstrated	demonstrate	VERB
bptjm-29	348	7	that	that	SCONJ
bptjm-29	348	8	the	the	DET
bptjm-29	348	9	functioning	functioning	NOUN
bptjm-29	348	10	of	of	ADP
bptjm-29	348	11	mscs	msc	NOUN
bptjm-29	348	12	declines	decline	NOUN
bptjm-29	348	13	with	with	ADP
bptjm-29	348	14	age	age	NOUN
bptjm-29	348	15	,	,	PUNCT
bptjm-29	348	16	and	and	CCONJ
bptjm-29	348	17	this	this	DET
bptjm-29	348	18	degradation	degradation	NOUN
bptjm-29	348	19	of	of	ADP
bptjm-29	348	20	function	function	NOUN
bptjm-29	348	21	can	can	AUX
bptjm-29	348	22	be	be	AUX
bptjm-29	348	23	implicated	implicate	VERB
bptjm-29	348	24	in	in	ADP
bptjm-29	348	25	the	the	DET
bptjm-29	348	26	loss	loss	NOUN
bptjm-29	348	27	of	of	ADP
bptjm-29	348	28	tissue	tissue	NOUN
bptjm-29	348	29	integrity	integrity	NOUN
bptjm-29	348	30	and	and	CCONJ
bptjm-29	348	31	homeostasis8	homeostasis8	NOUN
bptjm-29	348	32	.	.	PUNCT
bptjm-29	349	1	interestingly	interestingly	ADV
bptjm-29	349	2	,	,	PUNCT
bptjm-29	349	3	the	the	DET
bptjm-29	349	4	functional	functional	ADJ
bptjm-29	349	5	activity	activity	NOUN
bptjm-29	349	6	of	of	ADP
bptjm-29	349	7	mscs	msc	NOUN
bptjm-29	349	8	typically	typically	ADV
bptjm-29	349	9	declines	decline	VERB
bptjm-29	349	10	during	during	ADP
bptjm-29	349	11	and	and	CCONJ
bptjm-29	349	12	as	as	ADP
bptjm-29	349	13	a	a	DET
bptjm-29	349	14	consequence	consequence	NOUN
bptjm-29	349	15	of	of	ADP
bptjm-29	349	16	cell	cell	NOUN
bptjm-29	349	17	senescence	senescence	NOUN
bptjm-29	349	18	a	a	DET
bptjm-29	349	19	mechanism	mechanism	NOUN
bptjm-29	349	20	through	through	ADP
bptjm-29	349	21	which	which	PRON
bptjm-29	349	22	the	the	DET
bptjm-29	349	23	aging	aging	NOUN
bptjm-29	349	24	of	of	ADP
bptjm-29	349	25	a	a	DET
bptjm-29	349	26	cell	cell	NOUN
bptjm-29	349	27	occurs	occur	VERB
bptjm-29	349	28	and	and	CCONJ
bptjm-29	349	29	cellular	cellular	ADJ
bptjm-29	349	30	replication	replication	NOUN
bptjm-29	349	31	ceases	cease	VERB
bptjm-29	349	32	,	,	PUNCT
bptjm-29	349	33	with	with	ADP
bptjm-29	349	34	an	an	DET
bptjm-29	349	35	absence	absence	NOUN
bptjm-29	349	36	of	of	ADP
bptjm-29	349	37	cell	cell	NOUN
bptjm-29	349	38	death73	death73	NOUN
bptjm-29	349	39	.	.	PUNCT
bptjm-29	350	1	this	this	PRON
bptjm-29	350	2	can	can	AUX
bptjm-29	350	3	have	have	VERB
bptjm-29	350	4	a	a	DET
bptjm-29	350	5	signi	signi	ADJ
bptjm-29	350	6	�	�	NOUN
bptjm-29	350	7	cant	cant	VERB
bptjm-29	350	8	adverse	adverse	ADJ
bptjm-29	350	9	impact	impact	NOUN
bptjm-29	350	10	on	on	ADP
bptjm-29	350	11	msc	msc	PROPN
bptjm-29	350	12	function	function	NOUN
bptjm-29	350	13	when	when	SCONJ
bptjm-29	350	14	utilized	utilize	VERB
bptjm-29	350	15	for	for	ADP
bptjm-29	350	16	the	the	DET
bptjm-29	350	17	regeneration	regeneration	NOUN
bptjm-29	350	18	of	of	ADP
bptjm-29	350	19	injured	injure	VERB
bptjm-29	350	20	tissue	tissue	NOUN
bptjm-29	350	21	and	and	CCONJ
bptjm-29	350	22	therefore	therefore	ADV
bptjm-29	350	23	,	,	PUNCT
bptjm-29	350	24	strategies	strategy	NOUN
bptjm-29	350	25	to	to	PART
bptjm-29	350	26	prevent	prevent	VERB
bptjm-29	350	27	or	or	CCONJ
bptjm-29	350	28	delay	delay	VERB
bptjm-29	350	29	senescence	senescence	NOUN
bptjm-29	350	30	must	must	AUX
bptjm-29	350	31	be	be	AUX
bptjm-29	350	32	evaluated	evaluate	VERB
bptjm-29	350	33	in	in	ADP
bptjm-29	350	34	order	order	NOUN
bptjm-29	350	35	to	to	PART
bptjm-29	350	36	yield	yield	VERB
bptjm-29	350	37	a	a	DET
bptjm-29	350	38	longer	long	ADJ
bptjm-29	350	39	bene	bene	NOUN
bptjm-29	350	40	�	�	PROPN
bptjm-29	350	41	cial	cial	ADJ
bptjm-29	350	42	impact	impact	NOUN
bptjm-29	350	43	and	and	CCONJ
bptjm-29	350	44	increased	increase	VERB
bptjm-29	350	45	msc	msc	PROPN
bptjm-29	350	46	quality8	quality8	PROPN
bptjm-29	350	47	.	.	PUNCT
bptjm-29	351	1	it	it	PRON
bptjm-29	351	2	is	be	AUX
bptjm-29	351	3	relevant	relevant	ADJ
bptjm-29	351	4	to	to	PART
bptjm-29	351	5	note	note	VERB
bptjm-29	351	6	that	that	SCONJ
bptjm-29	351	7	a	a	DET
bptjm-29	351	8	comprehensive	comprehensive	ADJ
bptjm-29	351	9	study	study	NOUN
bptjm-29	351	10	of	of	ADP
bptjm-29	351	11	the	the	DET
bptjm-29	351	12	mechanisms	mechanism	NOUN
bptjm-29	351	13	of	of	ADP
bptjm-29	351	14	di	di	PROPN
bptjm-29	351	15	�	�	PROPN
bptjm-29	351	16	erentiation	erentiation	NOUN
bptjm-29	351	17	of	of	ADP
bptjm-29	351	18	stem	stem	NOUN
bptjm-29	351	19	cells	cell	NOUN
bptjm-29	351	20	can	can	AUX
bptjm-29	351	21	aid	aid	VERB
bptjm-29	351	22	in	in	ADP
bptjm-29	351	23	the	the	DET
bptjm-29	351	24	current	current	ADJ
bptjm-29	351	25	understanding	understanding	NOUN
bptjm-29	351	26	of	of	ADP
bptjm-29	351	27	how	how	SCONJ
bptjm-29	351	28	the	the	DET
bptjm-29	351	29	brain	brain	NOUN
bptjm-29	351	30	and	and	CCONJ
bptjm-29	351	31	spinal	spinal	ADJ
bptjm-29	351	32	cord	cord	NOUN
bptjm-29	351	33	can	can	AUX
bptjm-29	351	34	be	be	AUX
bptjm-29	351	35	individually	individually	ADV
bptjm-29	351	36	targeted	target	VERB
bptjm-29	351	37	to	to	PART
bptjm-29	351	38	stimulate	stimulate	VERB
bptjm-29	351	39	their	their	PRON
bptjm-29	351	40	repair74	repair74	NOUN
bptjm-29	351	41	.	.	PUNCT
bptjm-29	352	1	furthermore	furthermore	ADV
bptjm-29	352	2	,	,	PUNCT
bptjm-29	352	3	the	the	DET
bptjm-29	352	4	speci	speci	PROPN
bptjm-29	352	5	�	�	PROPN
bptjm-29	352	6	c	c	ADJ
bptjm-29	352	7	pathogenetic	pathogenetic	ADJ
bptjm-29	352	8	mechanisms	mechanism	NOUN
bptjm-29	352	9	of	of	ADP
bptjm-29	352	10	exosomes	exosome	NOUN
bptjm-29	352	11	,	,	PUNCT
bptjm-29	352	12	and	and	CCONJ
bptjm-29	352	13	their	their	PRON
bptjm-29	352	14	role	role	NOUN
bptjm-29	352	15	in	in	ADP
bptjm-29	352	16	therapeutic	therapeutic	ADJ
bptjm-29	352	17	applications	application	NOUN
bptjm-29	352	18	through	through	ADP
bptjm-29	352	19	their	their	PRON
bptjm-29	352	20	capacity	capacity	NOUN
bptjm-29	352	21	of	of	ADP
bptjm-29	352	22	cellular	cellular	ADJ
bptjm-29	352	23	repair	repair	NOUN
bptjm-29	352	24	should	should	AUX
bptjm-29	352	25	be	be	AUX
bptjm-29	352	26	further	far	ADV
bptjm-29	352	27	examined	examine	VERB
bptjm-29	352	28	.	.	PUNCT
bptjm-29	353	1	the	the	DET
bptjm-29	353	2	advantages	advantage	NOUN
bptjm-29	353	3	of	of	ADP
bptjm-29	353	4	msc	msc	PROPN
bptjm-29	353	5	derived	derive	VERB
bptjm-29	353	6	exosomes	exosome	NOUN
bptjm-29	353	7	/	/	SYM
bptjm-29	353	8	extracellular	extracellular	ADJ
bptjm-29	353	9	vesicles	vesicle	NOUN
bptjm-29	353	10	(	(	PUNCT
bptjm-29	353	11	ev	ev	X
bptjm-29	353	12	)	)	PUNCT
bptjm-29	353	13	have	have	AUX
bptjm-29	353	14	been	be	AUX
bptjm-29	353	15	elucidated	elucidate	VERB
bptjm-29	353	16	in	in	ADP
bptjm-29	353	17	this	this	DET
bptjm-29	353	18	paper	paper	NOUN
bptjm-29	353	19	;	;	PUNCT
bptjm-29	353	20	for	for	ADP
bptjm-29	353	21	instance	instance	NOUN
bptjm-29	353	22	,	,	PUNCT
bptjm-29	353	23	although	although	SCONJ
bptjm-29	353	24	these	these	DET
bptjm-29	353	25	evs	evs	NOUN
bptjm-29	353	26	have	have	AUX
bptjm-29	353	27	demonstrated	demonstrate	VERB
bptjm-29	353	28	bene	bene	PROPN
bptjm-29	353	29	�	�	PROPN
bptjm-29	353	30	cial	cial	ADJ
bptjm-29	353	31	e	e	NOUN
bptjm-29	353	32	�	�	NOUN
bptjm-29	353	33	ects	ect	NOUN
bptjm-29	353	34	in	in	ADP
bptjm-29	353	35	the	the	DET
bptjm-29	353	36	treatment	treatment	NOUN
bptjm-29	353	37	of	of	ADP
bptjm-29	353	38	malignancies	malignancy	NOUN
bptjm-29	353	39	,	,	PUNCT
bptjm-29	353	40	tumor	tumor	NOUN
bptjm-29	353	41	cells	cell	NOUN
bptjm-29	353	42	through	through	ADP
bptjm-29	353	43	evs	evs	NOUN
bptjm-29	353	44	have	have	VERB
bptjm-29	353	45	the	the	DET
bptjm-29	353	46	potency	potency	NOUN
bptjm-29	353	47	to	to	PART
bptjm-29	353	48	function	function	VERB
bptjm-29	353	49	as	as	ADP
bptjm-29	353	50	either	either	DET
bptjm-29	353	51	tumor	tumor	NOUN
bptjm-29	353	52	promoters	promoter	NOUN
bptjm-29	353	53	or	or	CCONJ
bptjm-29	353	54	suppressors	suppressor	NOUN
bptjm-29	353	55	.	.	PUNCT
bptjm-29	354	1	speci	speci	PROPN
bptjm-29	354	2	�	�	PROPN
bptjm-29	354	3	cally	cally	ADV
bptjm-29	354	4	,	,	PUNCT
bptjm-29	354	5	msc	msc	NOUN
bptjm-29	354	6	-	-	PUNCT
bptjm-29	354	7	derived	derive	VERB
bptjm-29	354	8	exosomes	exosome	NOUN
bptjm-29	354	9	have	have	AUX
bptjm-29	354	10	been	be	AUX
bptjm-29	354	11	reported	report	VERB
bptjm-29	354	12	to	to	PART
bptjm-29	354	13	be	be	AUX
bptjm-29	354	14	involved	involve	VERB
bptjm-29	354	15	with	with	ADP
bptjm-29	354	16	tumor	tumor	NOUN
bptjm-29	354	17	growth	growth	NOUN
bptjm-29	354	18	,	,	PUNCT
bptjm-29	354	19	angiogenesis	angiogenesis	NOUN
bptjm-29	354	20	,	,	PUNCT
bptjm-29	354	21	and	and	CCONJ
bptjm-29	354	22	metastasis	metastasis	NOUN
bptjm-29	354	23	.	.	PUNCT
bptjm-29	355	1	however	however	ADV
bptjm-29	355	2	,	,	PUNCT
bptjm-29	355	3	there	there	PRON
bptjm-29	355	4	does	do	AUX
bptjm-29	355	5	exist	exist	VERB
bptjm-29	355	6	a	a	DET
bptjm-29	355	7	discrepancy	discrepancy	NOUN
bptjm-29	355	8	between	between	ADP
bptjm-29	355	9	the	the	DET
bptjm-29	355	10	behaviors	behavior	NOUN
bptjm-29	355	11	of	of	ADP
bptjm-29	355	12	msc	msc	PROPN
bptjm-29	355	13	exosomes	exosome	NOUN
bptjm-29	355	14	,	,	PUNCT
bptjm-29	355	15	which	which	PRON
bptjm-29	355	16	may	may	AUX
bptjm-29	355	17	be	be	AUX
bptjm-29	355	18	associated	associate	VERB
bptjm-29	355	19	with	with	ADP
bptjm-29	355	20	the	the	DET
bptjm-29	355	21	sources	source	NOUN
bptjm-29	355	22	of	of	ADP
bptjm-29	355	23	mscs	msc	NOUN
bptjm-29	355	24	,	,	PUNCT
bptjm-29	355	25	genotypic	genotypic	ADJ
bptjm-29	355	26	characteristics	characteristic	NOUN
bptjm-29	355	27	of	of	ADP
bptjm-29	355	28	tumors	tumor	NOUN
bptjm-29	355	29	,	,	PUNCT
bptjm-29	355	30	and	and	CCONJ
bptjm-29	355	31	the	the	DET
bptjm-29	355	32	stages	stage	NOUN
bptjm-29	355	33	of	of	ADP
bptjm-29	355	34	tumor	tumor	NOUN
bptjm-29	355	35	growth8	growth8	NOUN
bptjm-29	355	36	.	.	PUNCT
bptjm-29	356	1	thus	thus	ADV
bptjm-29	356	2	,	,	PUNCT
bptjm-29	356	3	the	the	DET
bptjm-29	356	4	side	side	NOUN
bptjm-29	356	5	e	e	NOUN
bptjm-29	356	6	�	�	NOUN
bptjm-29	356	7	ects	ect	NOUN
bptjm-29	356	8	and	and	CCONJ
bptjm-29	356	9	implications	implication	NOUN
bptjm-29	356	10	of	of	ADP
bptjm-29	356	11	msc	msc	NOUN
bptjm-29	356	12	-	-	PUNCT
bptjm-29	356	13	derived	derive	VERB
bptjm-29	356	14	evs	evs	NOUN
bptjm-29	356	15	must	must	AUX
bptjm-29	356	16	be	be	AUX
bptjm-29	356	17	further	far	ADV
bptjm-29	356	18	investigated	investigate	VERB
bptjm-29	356	19	.	.	PUNCT
bptjm-29	357	1	berkeley	berkeley	PROPN
bptjm-29	357	2	pharma	pharma	PROPN
bptjm-29	357	3	tech	tech	PROPN
bptjm-29	357	4	journal	journal	NOUN
bptjm-29	357	5	of	of	ADP
bptjm-29	357	6	medicine	medicine	NOUN
bptjm-29	357	7	|	|	ADV
bptjm-29	357	8	96	96	NUM
bptjm-29	357	9	https://www.zotero.org/google-docs/?sgt1ox	https://www.zotero.org/google-docs/?sgt1ox	VERB
bptjm-29	357	10	https://www.zotero.org/google-docs/?t1nezd	https://www.zotero.org/google-docs/?t1nezd	NOUN
bptjm-29	357	11	https://www.zotero.org/google-docs/?ycqqyb	https://www.zotero.org/google-docs/?ycqqyb	PROPN
bptjm-29	358	1	https://www.zotero.org/google-docs/?zznzbq	https://www.zotero.org/google-docs/?zznzbq	PROPN
bptjm-29	358	2	https://www.zotero.org/google-docs/?ccyomy	https://www.zotero.org/google-docs/?ccyomy	ADJ
bptjm-29	358	3	https://www.zotero.org/google-docs/?mvbxmk	https://www.zotero.org/google-docs/?mvbxmk	PROPN
bptjm-29	358	4	most	most	ADV
bptjm-29	358	5	signi	signi	ADJ
bptjm-29	358	6	�	�	NOUN
bptjm-29	358	7	cantly	cantly	ADV
bptjm-29	358	8	,	,	PUNCT
bptjm-29	358	9	the	the	DET
bptjm-29	358	10	protocols	protocol	NOUN
bptjm-29	358	11	for	for	ADP
bptjm-29	358	12	inducing	induce	VERB
bptjm-29	358	13	cellular	cellular	ADJ
bptjm-29	358	14	di	di	NOUN
bptjm-29	358	15	�	�	PROPN
bptjm-29	358	16	erentiation	erentiation	NOUN
bptjm-29	358	17	into	into	ADP
bptjm-29	358	18	mscs	msc	NOUN
bptjm-29	358	19	can	can	AUX
bptjm-29	358	20	not	not	PART
bptjm-29	358	21	be	be	AUX
bptjm-29	358	22	directly	directly	ADV
bptjm-29	358	23	incorporated	incorporate	VERB
bptjm-29	358	24	within	within	ADP
bptjm-29	358	25	human	human	ADJ
bptjm-29	358	26	beings	being	NOUN
bptjm-29	358	27	due	due	ADP
bptjm-29	358	28	to	to	ADP
bptjm-29	358	29	their	their	PRON
bptjm-29	358	30	incorporation	incorporation	NOUN
bptjm-29	358	31	of	of	ADP
bptjm-29	358	32	toxic	toxic	ADJ
bptjm-29	358	33	chemicals75	chemicals75	NOUN
bptjm-29	358	34	.	.	PUNCT
bptjm-29	359	1	this	this	DET
bptjm-29	359	2	warrants	warrant	NOUN
bptjm-29	359	3	further	far	ADV
bptjm-29	359	4	study	study	VERB
bptjm-29	359	5	into	into	ADP
bptjm-29	359	6	the	the	DET
bptjm-29	359	7	development	development	NOUN
bptjm-29	359	8	of	of	ADP
bptjm-29	359	9	induction	induction	NOUN
bptjm-29	359	10	methods	method	NOUN
bptjm-29	359	11	that	that	PRON
bptjm-29	359	12	can	can	AUX
bptjm-29	359	13	be	be	AUX
bptjm-29	359	14	safely	safely	ADV
bptjm-29	359	15	executed	execute	VERB
bptjm-29	359	16	within	within	ADP
bptjm-29	359	17	patients	patient	NOUN
bptjm-29	359	18	.	.	PUNCT
bptjm-29	360	1	overall	overall	ADJ
bptjm-29	360	2	,	,	PUNCT
bptjm-29	360	3	though	though	ADV
bptjm-29	360	4	,	,	PUNCT
bptjm-29	360	5	the	the	DET
bptjm-29	360	6	mechanisms	mechanism	NOUN
bptjm-29	360	7	of	of	ADP
bptjm-29	360	8	mscs	msc	NOUN
bptjm-29	360	9	,	,	PUNCT
bptjm-29	360	10	in	in	ADP
bptjm-29	360	11	addition	addition	NOUN
bptjm-29	360	12	to	to	ADP
bptjm-29	360	13	their	their	PRON
bptjm-29	360	14	capacity	capacity	NOUN
bptjm-29	360	15	as	as	ADP
bptjm-29	360	16	a	a	DET
bptjm-29	360	17	universal	universal	ADJ
bptjm-29	360	18	therapeutic	therapeutic	ADJ
bptjm-29	360	19	within	within	ADP
bptjm-29	360	20	a	a	DET
bptjm-29	360	21	clinical	clinical	ADJ
bptjm-29	360	22	setting	setting	NOUN
bptjm-29	360	23	for	for	ADP
bptjm-29	360	24	als	al	NOUN
bptjm-29	360	25	and	and	CCONJ
bptjm-29	360	26	similar	similar	ADJ
bptjm-29	360	27	degenerative	degenerative	ADJ
bptjm-29	360	28	diseases	disease	NOUN
bptjm-29	360	29	needs	need	VERB
bptjm-29	360	30	to	to	PART
bptjm-29	360	31	be	be	AUX
bptjm-29	360	32	examined	examine	VERB
bptjm-29	360	33	to	to	ADP
bptjm-29	360	34	a	a	DET
bptjm-29	360	35	greater	great	ADJ
bptjm-29	360	36	extent	extent	NOUN
bptjm-29	360	37	,	,	PUNCT
bptjm-29	360	38	in	in	ADP
bptjm-29	360	39	order	order	NOUN
bptjm-29	360	40	to	to	PART
bptjm-29	360	41	gain	gain	VERB
bptjm-29	360	42	an	an	DET
bptjm-29	360	43	increased	increase	VERB
bptjm-29	360	44	understanding	understanding	NOUN
bptjm-29	360	45	of	of	ADP
bptjm-29	360	46	the	the	DET
bptjm-29	360	47	current	current	ADJ
bptjm-29	360	48	state	state	NOUN
bptjm-29	360	49	and	and	CCONJ
bptjm-29	360	50	application	application	NOUN
bptjm-29	360	51	potential	potential	NOUN
bptjm-29	360	52	of	of	ADP
bptjm-29	360	53	mscs	msc	NOUN
bptjm-29	360	54	,	,	PUNCT
bptjm-29	360	55	as	as	ADV
bptjm-29	360	56	well	well	ADV
bptjm-29	360	57	as	as	ADP
bptjm-29	360	58	of	of	ADP
bptjm-29	360	59	methods	method	NOUN
bptjm-29	360	60	that	that	PRON
bptjm-29	360	61	could	could	AUX
bptjm-29	360	62	be	be	AUX
bptjm-29	360	63	implemented	implement	VERB
bptjm-29	360	64	to	to	PART
bptjm-29	360	65	circumvent	circumvent	VERB
bptjm-29	360	66	the	the	DET
bptjm-29	360	67	potential	potential	ADJ
bptjm-29	360	68	risks	risk	NOUN
bptjm-29	360	69	associated	associate	VERB
bptjm-29	360	70	with	with	ADP
bptjm-29	360	71	the	the	DET
bptjm-29	360	72	administration	administration	NOUN
bptjm-29	360	73	of	of	ADP
bptjm-29	360	74	mscs	msc	NOUN
bptjm-29	360	75	.	.	PUNCT
bptjm-29	361	1	10	10	NUM
bptjm-29	361	2	.	.	X
bptjm-29	362	1	conclusion	conclusion	NOUN
bptjm-29	362	2	amyotrophic	amyotrophic	ADJ
bptjm-29	362	3	lateral	lateral	ADJ
bptjm-29	362	4	sclerosis	sclerosis	NOUN
bptjm-29	362	5	is	be	AUX
bptjm-29	362	6	a	a	DET
bptjm-29	362	7	rare	rare	ADJ
bptjm-29	362	8	and	and	CCONJ
bptjm-29	362	9	progressive	progressive	ADJ
bptjm-29	362	10	neurodegenerative	neurodegenerative	ADJ
bptjm-29	362	11	disease	disease	NOUN
bptjm-29	362	12	with	with	ADP
bptjm-29	362	13	no	no	DET
bptjm-29	362	14	cure	cure	NOUN
bptjm-29	362	15	to	to	ADP
bptjm-29	362	16	date	date	NOUN
bptjm-29	362	17	.	.	PUNCT
bptjm-29	363	1	while	while	SCONJ
bptjm-29	363	2	the	the	DET
bptjm-29	363	3	causes	cause	NOUN
bptjm-29	363	4	of	of	ADP
bptjm-29	363	5	als	als	NOUN
bptjm-29	363	6	remains	remain	VERB
bptjm-29	363	7	unclear	unclear	ADJ
bptjm-29	363	8	,	,	PUNCT
bptjm-29	363	9	current	current	ADJ
bptjm-29	363	10	theories	theory	NOUN
bptjm-29	363	11	for	for	ADP
bptjm-29	363	12	als	als	NOUN
bptjm-29	363	13	pathogenesis	pathogenesis	NOUN
bptjm-29	363	14	include	include	VERB
bptjm-29	363	15	mitochondrial	mitochondrial	ADJ
bptjm-29	363	16	damage	damage	NOUN
bptjm-29	363	17	,	,	PUNCT
bptjm-29	363	18	glutamate	glutamate	VERB
bptjm-29	363	19	excitotoxicity	excitotoxicity	NOUN
bptjm-29	363	20	,	,	PUNCT
bptjm-29	363	21	neuroin	neuroin	NOUN
bptjm-29	363	22	�	�	PROPN
bptjm-29	363	23	ammation	ammation	NOUN
bptjm-29	363	24	,	,	PUNCT
bptjm-29	363	25	and	and	CCONJ
bptjm-29	363	26	oxidative	oxidative	ADJ
bptjm-29	363	27	stress	stress	NOUN
bptjm-29	363	28	.	.	PUNCT
bptjm-29	364	1	existing	exist	VERB
bptjm-29	364	2	treatments	treatment	NOUN
bptjm-29	364	3	to	to	PART
bptjm-29	364	4	slow	slow	VERB
bptjm-29	364	5	the	the	DET
bptjm-29	364	6	degeneration	degeneration	NOUN
bptjm-29	364	7	of	of	ADP
bptjm-29	364	8	motor	motor	NOUN
bptjm-29	364	9	neurons	neuron	NOUN
bptjm-29	364	10	and	and	CCONJ
bptjm-29	364	11	extend	extend	VERB
bptjm-29	364	12	survival	survival	NOUN
bptjm-29	364	13	rates	rate	NOUN
bptjm-29	364	14	and/or	and/or	CCONJ
bptjm-29	364	15	time	time	NOUN
bptjm-29	364	16	to	to	ADP
bptjm-29	364	17	tracheostomy	tracheostomy	NOUN
bptjm-29	364	18	include	include	VERB
bptjm-29	364	19	therapeutics	therapeutic	NOUN
bptjm-29	364	20	like	like	ADP
bptjm-29	364	21	riluzole	riluzole	NOUN
bptjm-29	364	22	and	and	CCONJ
bptjm-29	364	23	edaravone	edaravone	NOUN
bptjm-29	364	24	,	,	PUNCT
bptjm-29	364	25	gene	gene	NOUN
bptjm-29	364	26	therapy	therapy	NOUN
bptjm-29	364	27	to	to	PART
bptjm-29	364	28	target	target	VERB
bptjm-29	364	29	als	al	NOUN
bptjm-29	364	30	-	-	PUNCT
bptjm-29	364	31	related	relate	VERB
bptjm-29	364	32	gene	gene	NOUN
bptjm-29	364	33	mutations	mutation	NOUN
bptjm-29	364	34	,	,	PUNCT
bptjm-29	364	35	and	and	CCONJ
bptjm-29	364	36	astrocyte	astrocyte	NOUN
bptjm-29	364	37	transplantations	transplantation	NOUN
bptjm-29	364	38	to	to	PART
bptjm-29	364	39	reverse	reverse	VERB
bptjm-29	364	40	neurotoxicity	neurotoxicity	NOUN
bptjm-29	364	41	in	in	ADP
bptjm-29	364	42	the	the	DET
bptjm-29	364	43	cns	cns	NOUN
bptjm-29	364	44	.	.	PUNCT
bptjm-29	365	1	however	however	ADV
bptjm-29	365	2	,	,	PUNCT
bptjm-29	365	3	the	the	DET
bptjm-29	365	4	mechanisms	mechanism	NOUN
bptjm-29	365	5	for	for	ADP
bptjm-29	365	6	these	these	DET
bptjm-29	365	7	therapies	therapy	NOUN
bptjm-29	365	8	are	be	AUX
bptjm-29	365	9	also	also	ADV
bptjm-29	365	10	not	not	PART
bptjm-29	365	11	well	well	ADV
bptjm-29	365	12	-	-	PUNCT
bptjm-29	365	13	understood	understand	VERB
bptjm-29	365	14	,	,	PUNCT
bptjm-29	365	15	and	and	CCONJ
bptjm-29	365	16	they	they	PRON
bptjm-29	365	17	are	be	AUX
bptjm-29	365	18	not	not	PART
bptjm-29	365	19	a	a	DET
bptjm-29	365	20	long	long	ADJ
bptjm-29	365	21	-	-	PUNCT
bptjm-29	365	22	term	term	NOUN
bptjm-29	365	23	solution	solution	NOUN
bptjm-29	365	24	.	.	PUNCT
bptjm-29	366	1	they	they	PRON
bptjm-29	366	2	mainly	mainly	ADV
bptjm-29	366	3	target	target	VERB
bptjm-29	366	4	one	one	NUM
bptjm-29	366	5	or	or	CCONJ
bptjm-29	366	6	two	two	NUM
bptjm-29	366	7	pathogenetic	pathogenetic	ADJ
bptjm-29	366	8	mechanisms	mechanism	NOUN
bptjm-29	366	9	or	or	CCONJ
bptjm-29	366	10	do	do	AUX
bptjm-29	366	11	not	not	PART
bptjm-29	366	12	provide	provide	VERB
bptjm-29	366	13	a	a	DET
bptjm-29	366	14	solution	solution	NOUN
bptjm-29	366	15	to	to	PART
bptjm-29	366	16	treat	treat	VERB
bptjm-29	366	17	all	all	DET
bptjm-29	366	18	als	als	NOUN
bptjm-29	366	19	cases	case	NOUN
bptjm-29	366	20	,	,	PUNCT
bptjm-29	366	21	so	so	SCONJ
bptjm-29	366	22	msc	msc	PROPN
bptjm-29	366	23	therapy	therapy	NOUN
bptjm-29	366	24	may	may	AUX
bptjm-29	366	25	be	be	AUX
bptjm-29	366	26	the	the	DET
bptjm-29	366	27	answer	answer	NOUN
bptjm-29	366	28	to	to	ADP
bptjm-29	366	29	a	a	DET
bptjm-29	366	30	cure	cure	NOUN
bptjm-29	366	31	for	for	ADP
bptjm-29	366	32	als	al	NOUN
bptjm-29	366	33	.	.	PUNCT
bptjm-29	367	1	mesenchymal	mesenchymal	ADJ
bptjm-29	367	2	stem	stem	NOUN
bptjm-29	367	3	cells	cell	NOUN
bptjm-29	367	4	have	have	AUX
bptjm-29	367	5	been	be	AUX
bptjm-29	367	6	shown	show	VERB
bptjm-29	367	7	to	to	PART
bptjm-29	367	8	be	be	AUX
bptjm-29	367	9	a	a	DET
bptjm-29	367	10	promising	promising	ADJ
bptjm-29	367	11	therapeutic	therapeutic	NOUN
bptjm-29	367	12	for	for	ADP
bptjm-29	367	13	als	al	NOUN
bptjm-29	367	14	,	,	PUNCT
bptjm-29	367	15	based	base	VERB
bptjm-29	367	16	on	on	ADP
bptjm-29	367	17	preclinical	preclinical	ADJ
bptjm-29	367	18	and	and	CCONJ
bptjm-29	367	19	clinical	clinical	ADJ
bptjm-29	367	20	trials	trial	NOUN
bptjm-29	367	21	,	,	PUNCT
bptjm-29	367	22	due	due	ADP
bptjm-29	367	23	to	to	ADP
bptjm-29	367	24	their	their	PRON
bptjm-29	367	25	ability	ability	NOUN
bptjm-29	367	26	to	to	PART
bptjm-29	367	27	stimulate	stimulate	VERB
bptjm-29	367	28	tissue	tissue	NOUN
bptjm-29	367	29	repair	repair	NOUN
bptjm-29	367	30	by	by	ADP
bptjm-29	367	31	di	di	PROPN
bptjm-29	367	32	�	�	PROPN
bptjm-29	367	33	erentiating	erentiate	VERB
bptjm-29	367	34	into	into	ADP
bptjm-29	367	35	muscle	muscle	NOUN
bptjm-29	367	36	cells	cell	NOUN
bptjm-29	367	37	as	as	ADV
bptjm-29	367	38	well	well	ADV
bptjm-29	367	39	as	as	ADP
bptjm-29	367	40	providing	provide	VERB
bptjm-29	367	41	for	for	ADP
bptjm-29	367	42	means	mean	NOUN
bptjm-29	367	43	to	to	PART
bptjm-29	367	44	repair	repair	VERB
bptjm-29	367	45	damaged	damaged	ADJ
bptjm-29	367	46	tissue	tissue	NOUN
bptjm-29	367	47	.	.	PUNCT
bptjm-29	368	1	challenges	challenge	NOUN
bptjm-29	368	2	associated	associate	VERB
bptjm-29	368	3	with	with	ADP
bptjm-29	368	4	msc	msc	PROPN
bptjm-29	368	5	therapies	therapy	NOUN
bptjm-29	368	6	such	such	ADJ
bptjm-29	368	7	as	as	ADP
bptjm-29	368	8	the	the	DET
bptjm-29	368	9	high	high	ADJ
bptjm-29	368	10	risk	risk	NOUN
bptjm-29	368	11	and	and	CCONJ
bptjm-29	368	12	irreversibility	irreversibility	NOUN
bptjm-29	368	13	deem	deem	VERB
bptjm-29	368	14	it	it	PRON
bptjm-29	368	15	essential	essential	ADJ
bptjm-29	368	16	for	for	ADP
bptjm-29	368	17	further	further	ADJ
bptjm-29	368	18	research	research	NOUN
bptjm-29	368	19	on	on	ADP
bptjm-29	368	20	the	the	DET
bptjm-29	368	21	administration	administration	NOUN
bptjm-29	368	22	of	of	ADP
bptjm-29	368	23	msc	msc	PROPN
bptjm-29	368	24	treatments	treatment	NOUN
bptjm-29	368	25	for	for	ADP
bptjm-29	368	26	als	al	NOUN
bptjm-29	368	27	.	.	PUNCT
bptjm-29	369	1	berkeley	berkeley	PROPN
bptjm-29	369	2	pharma	pharma	PROPN
bptjm-29	369	3	tech	tech	PROPN
bptjm-29	369	4	journal	journal	NOUN
bptjm-29	369	5	of	of	ADP
bptjm-29	369	6	medicine	medicine	NOUN
bptjm-29	369	7	|	|	ADV
bptjm-29	369	8	97	97	NUM
bptjm-29	369	9	https://www.zotero.org/google-docs/?gkkvkt	https://www.zotero.org/google-docs/?gkkvkt	ADJ
bptjm-29	369	10	con	con	PROPN
bptjm-29	369	11	�	�	PROPN
bptjm-29	369	12	icts	ict	NOUN
bptjm-29	369	13	of	of	ADP
bptjm-29	369	14	interest	interest	NOUN
bptjm-29	369	15	the	the	DET
bptjm-29	369	16	authors	author	NOUN
bptjm-29	369	17	declare	declare	VERB
bptjm-29	369	18	that	that	SCONJ
bptjm-29	369	19	there	there	PRON
bptjm-29	369	20	is	be	VERB
bptjm-29	369	21	no	no	DET
bptjm-29	369	22	con	con	PROPN
bptjm-29	369	23	�	�	PROPN
bptjm-29	369	24	ict	ict	PROPN
bptjm-29	369	25	of	of	ADP
bptjm-29	369	26	interest	interest	NOUN
bptjm-29	369	27	regarding	regard	VERB
bptjm-29	369	28	the	the	DET
bptjm-29	369	29	publication	publication	NOUN
bptjm-29	369	30	of	of	ADP
bptjm-29	369	31	this	this	DET
bptjm-29	369	32	paper	paper	NOUN
bptjm-29	369	33	.	.	PUNCT
bptjm-29	370	1	berkeley	berkeley	PROPN
bptjm-29	370	2	pharma	pharma	PROPN
bptjm-29	370	3	tech	tech	PROPN
bptjm-29	370	4	journal	journal	NOUN
bptjm-29	370	5	of	of	ADP
bptjm-29	370	6	medicine	medicine	NOUN
bptjm-29	370	7	|	|	ADV
bptjm-29	370	8	98	98	NUM
bptjm-29	370	9	references	reference	NOUN
bptjm-29	370	10	1	1	NUM
bptjm-29	370	11	.	.	PUNCT
bptjm-29	371	1	what	what	PRON
bptjm-29	371	2	is	be	AUX
bptjm-29	371	3	als	als	ADJ
bptjm-29	371	4	?	?	PUNCT
bptjm-29	372	1	amyotrophic	amyotrophic	ADJ
bptjm-29	372	2	lateral	lateral	ADJ
bptjm-29	372	3	sclerosis	sclerosis	NOUN
bptjm-29	372	4	|	|	ADP
bptjm-29	372	5	the	the	DET
bptjm-29	372	6	als	als	NOUN
bptjm-29	372	7	association	association	PROPN
bptjm-29	372	8	.	.	PUNCT
bptjm-29	373	1	accessed	access	VERB
bptjm-29	373	2	july	july	PROPN
bptjm-29	373	3	23	23	NUM
bptjm-29	373	4	,	,	PUNCT
bptjm-29	373	5	2022	2022	NUM
bptjm-29	373	6	.	.	PUNCT
bptjm-29	373	7	https://www.als.org/understanding-als/what-is-als	https://www.als.org/understanding-als/what-is-al	VERB
bptjm-29	374	1	2	2	NUM
bptjm-29	374	2	.	.	X
bptjm-29	375	1	about	about	ADP
bptjm-29	375	2	motor	motor	NOUN
bptjm-29	375	3	neurons	neuron	NOUN
bptjm-29	375	4	|	|	ADP
bptjm-29	375	5	columbia	columbia	PROPN
bptjm-29	375	6	university	university	PROPN
bptjm-29	375	7	motor	motor	PROPN
bptjm-29	375	8	neuron	neuron	PROPN
bptjm-29	375	9	center	center	PROPN
bptjm-29	375	10	.	.	PUNCT
bptjm-29	376	1	accessed	access	VERB
bptjm-29	376	2	july	july	PROPN
bptjm-29	376	3	23	23	NUM
bptjm-29	376	4	,	,	PUNCT
bptjm-29	376	5	2022	2022	NUM
bptjm-29	376	6	.	.	PUNCT
bptjm-29	377	1	https://www.columbiamnc.org/about-us/about-motorneurons	https://www.columbiamnc.org/about-us/about-motorneuron	NOUN
bptjm-29	377	2	3	3	NUM
bptjm-29	377	3	.	.	PUNCT
bptjm-29	377	4	lou	lou	PROPN
bptjm-29	377	5	gehrig	gehrig	PROPN
bptjm-29	377	6	and	and	CCONJ
bptjm-29	377	7	the	the	DET
bptjm-29	377	8	history	history	NOUN
bptjm-29	377	9	of	of	ADP
bptjm-29	377	10	als	al	NOUN
bptjm-29	377	11	.	.	PUNCT
bptjm-29	378	1	the	the	DET
bptjm-29	378	2	als	als	NOUN
bptjm-29	378	3	association	association	PROPN
bptjm-29	378	4	.	.	PUNCT
bptjm-29	378	5	accessed	access	VERB
bptjm-29	378	6	july	july	PROPN
bptjm-29	378	7	23	23	NUM
bptjm-29	378	8	,	,	PUNCT
bptjm-29	378	9	2022	2022	NUM
bptjm-29	378	10	.	.	PUNCT
bptjm-29	379	1	https://www.als.org/understanding-als/lou-gehrig	https://www.als.org/understanding-als/lou-gehrig	NOUN
bptjm-29	379	2	4	4	NUM
bptjm-29	379	3	.	.	PUNCT
bptjm-29	380	1	early	early	ADJ
bptjm-29	380	2	symptoms	symptom	NOUN
bptjm-29	380	3	of	of	ADP
bptjm-29	380	4	als	al	NOUN
bptjm-29	380	5	/	/	SYM
bptjm-29	380	6	mnd	mnd	PROPN
bptjm-29	380	7	|	|	NOUN
bptjm-29	380	8	als	als	VERB
bptjm-29	380	9	worldwide	worldwide	ADV
bptjm-29	380	10	.	.	PUNCT
bptjm-29	381	1	accessed	access	VERB
bptjm-29	381	2	july	july	PROPN
bptjm-29	381	3	23	23	NUM
bptjm-29	381	4	,	,	PUNCT
bptjm-29	381	5	2022	2022	NUM
bptjm-29	381	6	.	.	PUNCT
bptjm-29	382	1	https://alsworldwide.org/care-and-support/article/earlysymptoms-of-als-mnd	https://alsworldwide.org/care-and-support/article/earlysymptoms-of-als-mnd	ADP
bptjm-29	382	2	5	5	X
bptjm-29	382	3	.	.	X
bptjm-29	382	4	stages	stage	NOUN
bptjm-29	382	5	of	of	ADP
bptjm-29	382	6	amyotrophic	amyotrophic	ADJ
bptjm-29	382	7	lateral	lateral	ADJ
bptjm-29	382	8	sclerosis	sclerosis	NOUN
bptjm-29	382	9	(	(	PUNCT
bptjm-29	382	10	als	als	NOUN
bptjm-29	382	11	)	)	PUNCT
bptjm-29	382	12	diseases	disease	NOUN
bptjm-29	382	13	|	|	ADV
bptjm-29	382	14	muscular	muscular	ADJ
bptjm-29	382	15	dystrophy	dystrophy	NOUN
bptjm-29	382	16	association	association	NOUN
bptjm-29	382	17	.	.	PUNCT
bptjm-29	383	1	accessed	access	VERB
bptjm-29	383	2	july	july	PROPN
bptjm-29	383	3	23	23	NUM
bptjm-29	383	4	,	,	PUNCT
bptjm-29	383	5	2022	2022	NUM
bptjm-29	383	6	.	.	PUNCT
bptjm-29	384	1	https://www.mda.org/disease/amyotrophic-lateral-sclero	https://www.mda.org/disease/amyotrophic-lateral-sclero	NUM
bptjm-29	384	2	sis	sis	NOUN
bptjm-29	384	3	/	/	SYM
bptjm-29	384	4	signs	sign	NOUN
bptjm-29	384	5	-	-	PUNCT
bptjm-29	384	6	and	and	CCONJ
bptjm-29	384	7	-	-	PUNCT
bptjm-29	384	8	symptoms	symptom	NOUN
bptjm-29	384	9	/	/	SYM
bptjm-29	384	10	stages	stage	NOUN
bptjm-29	384	11	-	-	PUNCT
bptjm-29	384	12	of	of	ADP
bptjm-29	384	13	-	-	PUNCT
bptjm-29	384	14	als	als	NOUN
bptjm-29	384	15	6	6	NUM
bptjm-29	384	16	.	.	PUNCT
bptjm-29	384	17	als	al	NOUN
bptjm-29	384	18	,	,	PUNCT
bptjm-29	384	19	amyotrophic	amyotrophic	ADJ
bptjm-29	384	20	lateral	lateral	ADJ
bptjm-29	384	21	sclerosis	sclerosis	NOUN
bptjm-29	384	22	,	,	PUNCT
bptjm-29	384	23	lou	lou	PROPN
bptjm-29	384	24	gehrig	gehrig	PROPN
bptjm-29	384	25	’s	’s	PART
bptjm-29	384	26	disease	disease	NOUN
bptjm-29	384	27	.	.	PUNCT
bptjm-29	385	1	accessed	access	VERB
bptjm-29	385	2	july	july	PROPN
bptjm-29	385	3	23	23	NUM
bptjm-29	385	4	,	,	PUNCT
bptjm-29	385	5	2022	2022	NUM
bptjm-29	385	6	.	.	PUNCT
bptjm-29	386	1	https://www.hopkinsmedicine.org/neurology_neurosur	https://www.hopkinsmedicine.org/neurology_neurosur	PROPN
bptjm-29	386	2	gery	gery	PROPN
bptjm-29	386	3	/	/	SYM
bptjm-29	386	4	centers_clinics	centers_clinics	PROPN
bptjm-29	386	5	/	/	SYM
bptjm-29	386	6	als	al	NOUN
bptjm-29	386	7	/	/	SYM
bptjm-29	386	8	conditions	condition	NOUN
bptjm-29	386	9	/	/	SYM
bptjm-29	386	10	als_amyotrophic_late	als_amyotrophic_late	VERB
bptjm-29	386	11	ral_sclerosis.html	ral_sclerosis.html	NUM
bptjm-29	386	12	7	7	NUM
bptjm-29	386	13	.	.	PUNCT
bptjm-29	386	14	bonafede	bonafede	NOUN
bptjm-29	386	15	r	r	PROPN
bptjm-29	386	16	,	,	PUNCT
bptjm-29	386	17	mariotti	mariotti	PROPN
bptjm-29	386	18	r.	r.	PROPN
bptjm-29	386	19	als	als	VERB
bptjm-29	386	20	pathogenesis	pathogenesis	NOUN
bptjm-29	386	21	and	and	CCONJ
bptjm-29	386	22	therapeutic	therapeutic	ADJ
bptjm-29	386	23	approaches	approach	NOUN
bptjm-29	386	24	:	:	PUNCT
bptjm-29	386	25	the	the	DET
bptjm-29	386	26	role	role	NOUN
bptjm-29	386	27	of	of	ADP
bptjm-29	386	28	mesenchymal	mesenchymal	ADJ
bptjm-29	386	29	stem	stem	NOUN
bptjm-29	386	30	cells	cell	NOUN
bptjm-29	386	31	and	and	CCONJ
bptjm-29	386	32	extracellular	extracellular	ADJ
bptjm-29	386	33	vesicles	vesicle	NOUN
bptjm-29	386	34	.	.	PUNCT
bptjm-29	387	1	front	front	ADJ
bptjm-29	387	2	cell	cell	NOUN
bptjm-29	387	3	neurosci	neurosci	NOUN
bptjm-29	387	4	.	.	PUNCT
bptjm-29	388	1	2017;11:80	2017;11:80	X
bptjm-29	388	2	.	.	PUNCT
bptjm-29	389	1	doi:10.3389	doi:10.3389	PROPN
bptjm-29	389	2	/	/	SYM
bptjm-29	389	3	fncel.2017.00080	fncel.2017.00080	PROPN
bptjm-29	389	4	8	8	NUM
bptjm-29	389	5	.	.	PUNCT
bptjm-29	390	1	mitochondrial	mitochondrial	ADJ
bptjm-29	390	2	dysfunction	dysfunction	NOUN
bptjm-29	390	3	in	in	ADP
bptjm-29	390	4	als	als	NOUN
bptjm-29	390	5	sciencedirect	sciencedirect	PROPN
bptjm-29	390	6	.	.	PUNCT
bptjm-29	391	1	accessed	access	VERB
bptjm-29	391	2	july	july	PROPN
bptjm-29	391	3	23	23	NUM
bptjm-29	391	4	,	,	PUNCT
bptjm-29	391	5	2022	2022	NUM
bptjm-29	391	6	.	.	PUNCT
bptjm-29	392	1	https://www.sciencedirect.com/science/article/pii/s030	https://www.sciencedirect.com/science/article/pii/s030	PROPN
bptjm-29	392	2	1008211000918?via%3dihub	1008211000918?via%3dihub	NUM
bptjm-29	392	3	9	9	NUM
bptjm-29	392	4	.	.	PUNCT
bptjm-29	392	5	czarzasta	czarzasta	PROPN
bptjm-29	392	6	j	j	PROPN
bptjm-29	392	7	,	,	PUNCT
bptjm-29	392	8	habich	habich	X
bptjm-29	392	9	a	a	X
bptjm-29	392	10	,	,	PUNCT
bptjm-29	392	11	siwek	siwek	PROPN
bptjm-29	392	12	t	t	PROPN
bptjm-29	392	13	,	,	PUNCT
bptjm-29	392	14	czapliński	czapliński	PROPN
bptjm-29	392	15	a	a	PROPN
bptjm-29	392	16	,	,	PUNCT
bptjm-29	392	17	maksymowicz	maksymowicz	PROPN
bptjm-29	392	18	w	w	PROPN
bptjm-29	392	19	,	,	PUNCT
bptjm-29	392	20	wojtkiewicz	wojtkiewicz	PROPN
bptjm-29	392	21	j.	j.	PROPN
bptjm-29	392	22	stem	stem	NOUN
bptjm-29	392	23	cells	cell	NOUN
bptjm-29	392	24	for	for	ADP
bptjm-29	392	25	als	al	NOUN
bptjm-29	392	26	:	:	PUNCT
bptjm-29	392	27	an	an	DET
bptjm-29	392	28	overview	overview	NOUN
bptjm-29	392	29	of	of	ADP
bptjm-29	392	30	possible	possible	ADJ
bptjm-29	392	31	therapeutic	therapeutic	ADJ
bptjm-29	392	32	approaches	approach	NOUN
bptjm-29	392	33	.	.	PUNCT
bptjm-29	393	1	int	int	PROPN
bptjm-29	393	2	j	j	PROPN
bptjm-29	393	3	dev	dev	PROPN
bptjm-29	393	4	neurosci	neurosci	PROPN
bptjm-29	393	5	.	.	PUNCT
bptjm-29	394	1	2017;57:46	2017;57:46	NUM
bptjm-29	394	2	-	-	SYM
bptjm-29	394	3	55	55	NUM
bptjm-29	394	4	.	.	PUNCT
bptjm-29	394	5	doi:10.1016	doi:10.1016	PROPN
bptjm-29	394	6	/	/	SYM
bptjm-29	394	7	j.ijdevneu.2017.01.003	j.ijdevneu.2017.01.003	PROPN
bptjm-29	394	8	10	10	NUM
bptjm-29	394	9	.	.	PUNCT
bptjm-29	395	1	fan	fan	PROPN
bptjm-29	395	2	xl	xl	PROPN
bptjm-29	395	3	,	,	PUNCT
bptjm-29	395	4	zhang	zhang	PROPN
bptjm-29	395	5	y	y	PROPN
bptjm-29	395	6	,	,	PUNCT
bptjm-29	395	7	li	li	PROPN
bptjm-29	395	8	x	x	PROPN
bptjm-29	395	9	,	,	PUNCT
bptjm-29	395	10	fu	fu	PROPN
bptjm-29	395	11	ql	ql	PROPN
bptjm-29	395	12	.	.	PUNCT
bptjm-29	395	13	mechanisms	mechanism	NOUN
bptjm-29	395	14	underlying	underlie	VERB
bptjm-29	395	15	the	the	DET
bptjm-29	395	16	protective	protective	ADJ
bptjm-29	395	17	e	e	NOUN
bptjm-29	395	18	�	�	NOUN
bptjm-29	395	19	ects	ect	NOUN
bptjm-29	395	20	of	of	ADP
bptjm-29	395	21	mesenchymal	mesenchymal	NOUN
bptjm-29	395	22	stem	stem	NOUN
bptjm-29	395	23	cell	cell	NOUN
bptjm-29	395	24	-	-	PUNCT
bptjm-29	395	25	based	base	VERB
bptjm-29	395	26	therapy	therapy	NOUN
bptjm-29	395	27	.	.	PUNCT
bptjm-29	396	1	cell	cell	NOUN
bptjm-29	396	2	mol	mol	ADP
bptjm-29	396	3	life	life	PROPN
bptjm-29	396	4	sci	sci	PROPN
bptjm-29	396	5	.	.	PUNCT
bptjm-29	397	1	2020;77(14):2771	2020;77(14):2771	NUM
bptjm-29	397	2	-	-	SYM
bptjm-29	397	3	2794	2794	NUM
bptjm-29	397	4	.	.	PUNCT
bptjm-29	398	1	doi:10.1007	doi:10.1007	VERB
bptjm-29	398	2	/	/	SYM
bptjm-29	398	3	s00018	s00018	NOUN
bptjm-29	398	4	-	-	PUNCT
bptjm-29	398	5	020	020	NUM
bptjm-29	398	6	-	-	PUNCT
bptjm-29	398	7	03454	03454	NUM
bptjm-29	398	8	-	-	SYM
bptjm-29	398	9	6	6	NUM
bptjm-29	398	10	11	11	NUM
bptjm-29	398	11	.	.	PUNCT
bptjm-29	399	1	de	de	PROPN
bptjm-29	399	2	�	�	NOUN
bptjm-29	399	3	nition	nition	NOUN
bptjm-29	399	4	of	of	ADP
bptjm-29	399	5	apoptosis	apoptosis	NOUN
bptjm-29	399	6	nci	nci	PROPN
bptjm-29	399	7	dictionary	dictionary	PROPN
bptjm-29	399	8	of	of	ADP
bptjm-29	399	9	cancer	cancer	NOUN
bptjm-29	399	10	terms	term	NOUN
bptjm-29	399	11	nci	nci	PROPN
bptjm-29	399	12	.	.	PUNCT
bptjm-29	400	1	published	publish	VERB
bptjm-29	400	2	february	february	PROPN
bptjm-29	400	3	2	2	NUM
bptjm-29	400	4	,	,	PUNCT
bptjm-29	400	5	2011	2011	NUM
bptjm-29	400	6	.	.	PUNCT
bptjm-29	401	1	accessed	access	VERB
bptjm-29	401	2	july	july	PROPN
bptjm-29	401	3	23	23	NUM
bptjm-29	401	4	,	,	PUNCT
bptjm-29	401	5	2022	2022	NUM
bptjm-29	401	6	.	.	PUNCT
bptjm-29	402	1	https://www.cancer.gov/publications/dictionaries/cance	https://www.cancer.gov/publications/dictionaries/cance	NOUN
bptjm-29	403	1	r	r	NOUN
bptjm-29	403	2	-	-	PUNCT
bptjm-29	403	3	terms	term	NOUN
bptjm-29	403	4	/	/	SYM
bptjm-29	403	5	def	def	ADJ
bptjm-29	403	6	/	/	SYM
bptjm-29	403	7	apoptosis	apoptosis	NOUN
bptjm-29	403	8	12	12	NUM
bptjm-29	403	9	.	.	PUNCT
bptjm-29	404	1	bendotti	bendotti	PROPN
bptjm-29	404	2	c	c	PROPN
bptjm-29	404	3	,	,	PUNCT
bptjm-29	404	4	calvaresi	calvaresi	PROPN
bptjm-29	404	5	n	n	CCONJ
bptjm-29	404	6	,	,	PUNCT
bptjm-29	404	7	chiveri	chiveri	PROPN
bptjm-29	404	8	l	l	PROPN
bptjm-29	404	9	,	,	PUNCT
bptjm-29	404	10	et	et	PROPN
bptjm-29	404	11	al	al	PROPN
bptjm-29	404	12	.	.	PROPN
bptjm-29	405	1	early	early	ADJ
bptjm-29	405	2	vacuolization	vacuolization	NOUN
bptjm-29	405	3	and	and	CCONJ
bptjm-29	405	4	mitochondrial	mitochondrial	ADJ
bptjm-29	405	5	damage	damage	NOUN
bptjm-29	405	6	in	in	ADP
bptjm-29	405	7	motor	motor	NOUN
bptjm-29	405	8	neurons	neuron	NOUN
bptjm-29	405	9	of	of	ADP
bptjm-29	405	10	fals	fal	NOUN
bptjm-29	405	11	mice	mouse	NOUN
bptjm-29	405	12	are	be	AUX
bptjm-29	405	13	not	not	PART
bptjm-29	405	14	associated	associate	VERB
bptjm-29	405	15	with	with	ADP
bptjm-29	405	16	apoptosis	apoptosis	NOUN
bptjm-29	405	17	or	or	CCONJ
bptjm-29	405	18	with	with	ADP
bptjm-29	405	19	changes	change	NOUN
bptjm-29	405	20	in	in	ADP
bptjm-29	405	21	cytochrome	cytochrome	ADJ
bptjm-29	405	22	oxidase	oxidase	NOUN
bptjm-29	405	23	histochemical	histochemical	ADJ
bptjm-29	405	24	reactivity	reactivity	NOUN
bptjm-29	405	25	.	.	PUNCT
bptjm-29	406	1	j	j	PROPN
bptjm-29	406	2	neurol	neurol	PROPN
bptjm-29	406	3	sci	sci	PROPN
bptjm-29	406	4	.	.	PROPN
bptjm-29	406	5	2001;191(1	2001;191(1	NUM
bptjm-29	406	6	-	-	PUNCT
bptjm-29	406	7	2):25	2):25	NUM
bptjm-29	406	8	-	-	PUNCT
bptjm-29	406	9	33	33	NUM
bptjm-29	406	10	.	.	PUNCT
bptjm-29	406	11	doi:10.1016	doi:10.1016	PROPN
bptjm-29	406	12	/	/	SYM
bptjm-29	406	13	s0022	s0022	PROPN
bptjm-29	406	14	-	-	PUNCT
bptjm-29	406	15	510x(01)00627	510x(01)00627	NOUN
bptjm-29	406	16	-	-	PUNCT
bptjm-29	406	17	x	x	SYM
bptjm-29	406	18	13	13	NUM
bptjm-29	406	19	.	.	PUNCT
bptjm-29	407	1	verma	verma	PROPN
bptjm-29	407	2	m	m	PROPN
bptjm-29	407	3	,	,	PUNCT
bptjm-29	407	4	lizama	lizama	PROPN
bptjm-29	407	5	bn	bn	NUM
bptjm-29	407	6	,	,	PUNCT
bptjm-29	407	7	chu	chu	PROPN
bptjm-29	407	8	ct	ct	PROPN
bptjm-29	407	9	.	.	PUNCT
bptjm-29	408	1	excitotoxicity	excitotoxicity	NOUN
bptjm-29	408	2	,	,	PUNCT
bptjm-29	408	3	calcium	calcium	NOUN
bptjm-29	408	4	and	and	CCONJ
bptjm-29	408	5	mitochondria	mitochondria	PROPN
bptjm-29	408	6	:	:	PUNCT
bptjm-29	408	7	a	a	DET
bptjm-29	408	8	triad	triad	NOUN
bptjm-29	408	9	in	in	ADP
bptjm-29	408	10	synaptic	synaptic	ADJ
bptjm-29	408	11	neurodegeneration	neurodegeneration	NOUN
bptjm-29	408	12	.	.	PUNCT
bptjm-29	409	1	transl	transl	PROPN
bptjm-29	409	2	neurodegener	neurodegener	PROPN
bptjm-29	409	3	.	.	PUNCT
bptjm-29	410	1	2022;11(1):3	2022;11(1):3	NUM
bptjm-29	410	2	.	.	PUNCT
bptjm-29	411	1	published	publish	VERB
bptjm-29	411	2	2022	2022	NUM
bptjm-29	411	3	jan	jan	PROPN
bptjm-29	411	4	25	25	NUM
bptjm-29	411	5	.	.	PUNCT
bptjm-29	411	6	doi:10.1186	doi:10.1186	PROPN
bptjm-29	411	7	/	/	SYM
bptjm-29	411	8	s40035	s40035	PROPN
bptjm-29	411	9	-	-	PUNCT
bptjm-29	411	10	021	021	NUM
bptjm-29	411	11	-	-	PUNCT
bptjm-29	411	12	00278	00278	NUM
bptjm-29	411	13	-	-	SYM
bptjm-29	411	14	7	7	NUM
bptjm-29	411	15	14	14	NUM
bptjm-29	411	16	.	.	PUNCT
bptjm-29	412	1	glutamate	glutamate	NOUN
bptjm-29	412	2	:	:	PUNCT
bptjm-29	412	3	what	what	PRON
bptjm-29	412	4	it	it	PRON
bptjm-29	412	5	is	be	AUX
bptjm-29	412	6	&	&	CCONJ
bptjm-29	412	7	function	function	PROPN
bptjm-29	412	8	.	.	PUNCT
bptjm-29	413	1	cleveland	cleveland	PROPN
bptjm-29	413	2	clinic	clinic	PROPN
bptjm-29	413	3	.	.	PUNCT
bptjm-29	414	1	accessed	access	VERB
bptjm-29	414	2	july	july	PROPN
bptjm-29	414	3	23	23	NUM
bptjm-29	414	4	,	,	PUNCT
bptjm-29	414	5	2022	2022	NUM
bptjm-29	414	6	.	.	PUNCT
bptjm-29	415	1	https://my.clevelandclinic.org/health/articles/22839-glu	https://my.clevelandclinic.org/health/articles/22839-glu	NOUN
bptjm-29	415	2	tamate	tamate	NOUN
bptjm-29	415	3	15	15	NUM
bptjm-29	415	4	.	.	PUNCT
bptjm-29	416	1	neurotransmitters	neurotransmitter	NOUN
bptjm-29	416	2	:	:	PUNCT
bptjm-29	416	3	what	what	PRON
bptjm-29	416	4	they	they	PRON
bptjm-29	416	5	are	be	AUX
bptjm-29	416	6	,	,	PUNCT
bptjm-29	416	7	functions	function	NOUN
bptjm-29	416	8	&	&	CCONJ
bptjm-29	416	9	types	type	NOUN
bptjm-29	416	10	.	.	PUNCT
bptjm-29	417	1	cleveland	cleveland	PROPN
bptjm-29	417	2	clinic	clinic	PROPN
bptjm-29	417	3	.	.	PUNCT
bptjm-29	418	1	accessed	access	VERB
bptjm-29	418	2	july	july	PROPN
bptjm-29	418	3	23	23	NUM
bptjm-29	418	4	,	,	PUNCT
bptjm-29	418	5	2022	2022	NUM
bptjm-29	418	6	.	.	PUNCT
bptjm-29	419	1	https://my.clevelandclinic.org/health/articles/22513-neu	https://my.clevelandclinic.org/health/articles/22513-neu	PROPN
bptjm-29	419	2	rotransmitters	rotransmitter	NOUN
bptjm-29	419	3	16	16	NUM
bptjm-29	419	4	.	.	PUNCT
bptjm-29	420	1	riancho	riancho	PROPN
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bptjm-29	452	8	-	-	PUNCT
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bptjm-29	452	10	-	-	PUNCT
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bptjm-29	456	4	-	-	SYM
bptjm-29	456	5	8	8	NUM
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bptjm-29	456	7	doi:10.1016	doi:10.1016	PROPN
bptjm-29	456	8	/	/	SYM
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bptjm-29	456	10	-	-	PUNCT
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bptjm-29	456	12	-	-	PUNCT
bptjm-29	456	13	3	3	NUM
bptjm-29	456	14	26	26	NUM
bptjm-29	456	15	.	.	PUNCT
bptjm-29	457	1	li	li	PROPN
bptjm-29	457	2	r	r	PROPN
bptjm-29	457	3	,	,	PUNCT
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bptjm-29	457	5	z	z	PROPN
bptjm-29	457	6	,	,	PUNCT
bptjm-29	457	7	trush	trush	PROPN
bptjm-29	457	8	ma	ma	PROPN
bptjm-29	457	9	.	.	PROPN
bptjm-29	457	10	de	de	PROPN
bptjm-29	457	11	�	�	PROPN
bptjm-29	457	12	ning	ning	ADJ
bptjm-29	457	13	ros	ros	PROPN
bptjm-29	457	14	in	in	ADP
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bptjm-29	457	17	medicine	medicine	NOUN
bptjm-29	457	18	.	.	PUNCT
bptjm-29	458	1	react	react	VERB
bptjm-29	458	2	oxyg	oxyg	PROPN
bptjm-29	458	3	species	species	PROPN
bptjm-29	458	4	apex	apex	PROPN
bptjm-29	458	5	nc	nc	PROPN
bptjm-29	458	6	.	.	PROPN
bptjm-29	458	7	2016;1(1):9	2016;1(1):9	PROPN
bptjm-29	458	8	-	-	PUNCT
bptjm-29	458	9	21	21	NUM
bptjm-29	458	10	.	.	PUNCT
bptjm-29	459	1	doi:10.20455	doi:10.20455	NOUN
bptjm-29	459	2	/	/	SYM
bptjm-29	459	3	ros.2016.803	ros.2016.803	PROPN
bptjm-29	459	4	27	27	NUM
bptjm-29	459	5	.	.	PUNCT
bptjm-29	460	1	sod1	sod1	ADJ
bptjm-29	460	2	gene	gene	NOUN
bptjm-29	460	3	:	:	PUNCT
bptjm-29	460	4	medlineplus	medlineplus	ADJ
bptjm-29	460	5	genetics	genetic	NOUN
bptjm-29	460	6	.	.	PUNCT
bptjm-29	461	1	accessed	access	VERB
bptjm-29	461	2	july	july	PROPN
bptjm-29	461	3	23	23	NUM
bptjm-29	461	4	,	,	PUNCT
bptjm-29	461	5	2022	2022	NUM
bptjm-29	461	6	.	.	PUNCT
bptjm-29	462	1	https://medlineplus.gov/genetics/gene/sod1/	https://medlineplus.gov/genetics/gene/sod1/	PROPN
bptjm-29	462	2	28	28	NUM
bptjm-29	462	3	.	.	PUNCT
bptjm-29	463	1	riluzole	riluzole	NOUN
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bptjm-29	463	3	the	the	DET
bptjm-29	463	4	treatment	treatment	NOUN
bptjm-29	463	5	of	of	ADP
bptjm-29	463	6	amyotrophic	amyotrophic	ADJ
bptjm-29	463	7	lateral	lateral	ADJ
bptjm-29	463	8	sclerosis	sclerosis	NOUN
bptjm-29	463	9	|	|	ADV
bptjm-29	463	10	neurodegenerative	neurodegenerative	ADJ
bptjm-29	463	11	disease	disease	NOUN
bptjm-29	463	12	management	management	NOUN
bptjm-29	463	13	.	.	PUNCT
bptjm-29	464	1	accessed	access	VERB
bptjm-29	464	2	july	july	PROPN
bptjm-29	464	3	23	23	NUM
bptjm-29	464	4	,	,	PUNCT
bptjm-29	464	5	2022	2022	NUM
bptjm-29	464	6	.	.	PUNCT
bptjm-29	465	1	https://www.futuremedicine.com/doi/10.2217/nmt-20	https://www.futuremedicine.com/doi/10.2217/nmt-20	PROPN
bptjm-29	465	2	20	20	NUM
bptjm-29	465	3	-	-	PUNCT
bptjm-29	465	4	0033?url_ver	0033?url_ver	NOUN
bptjm-29	465	5	=	=	NOUN
bptjm-29	465	6	z39.88	z39.88	NUM
bptjm-29	465	7	-	-	PUNCT
bptjm-29	465	8	2003&rfr_id	2003&rfr_id	NUM
bptjm-29	465	9	=	=	NOUN
bptjm-29	465	10	ori%3arid%3ac	ori%3arid%3ac	PROPN
bptjm-29	465	11	rossref.org&rfr_dat	rossref.org&rfr_dat	NOUN
bptjm-29	465	12	=	=	NOUN
bptjm-29	465	13	cr_pub++0pubmed	cr_pub++0pubmed	NUM
bptjm-29	465	14	29	29	NUM
bptjm-29	465	15	.	.	PUNCT
bptjm-29	466	1	glutamate	glutamate	NOUN
bptjm-29	466	2	:	:	PUNCT
bptjm-29	466	3	function	function	NOUN
bptjm-29	466	4	,	,	PUNCT
bptjm-29	466	5	healthy	healthy	ADJ
bptjm-29	466	6	levels	level	NOUN
bptjm-29	466	7	,	,	PUNCT
bptjm-29	466	8	and	and	CCONJ
bptjm-29	466	9	more	more	ADJ
bptjm-29	466	10	.	.	PUNCT
bptjm-29	467	1	verywell	verywell	VERB
bptjm-29	467	2	health	health	NOUN
bptjm-29	467	3	.	.	PUNCT
bptjm-29	468	1	accessed	access	VERB
bptjm-29	468	2	july	july	PROPN
bptjm-29	468	3	23	23	NUM
bptjm-29	468	4	,	,	PUNCT
bptjm-29	468	5	2022	2022	NUM
bptjm-29	468	6	.	.	PUNCT
bptjm-29	469	1	https://www.verywellhealth.com/what-is-glutamate-518	https://www.verywellhealth.com/what-is-glutamate-518	ADJ
bptjm-29	469	2	8294	8294	NUM
bptjm-29	469	3	30	30	NUM
bptjm-29	469	4	.	.	PUNCT
bptjm-29	470	1	bensimon	bensimon	PROPN
bptjm-29	470	2	g	g	PROPN
bptjm-29	470	3	,	,	PUNCT
bptjm-29	470	4	lacomblez	lacomblez	PROPN
bptjm-29	470	5	l	l	NOUN
bptjm-29	470	6	,	,	PUNCT
bptjm-29	470	7	meininger	meininger	NOUN
bptjm-29	470	8	v.	v.	ADP
bptjm-29	470	9	a	a	DET
bptjm-29	470	10	controlled	control	VERB
bptjm-29	470	11	trial	trial	NOUN
bptjm-29	470	12	of	of	ADP
bptjm-29	470	13	riluzole	riluzole	NOUN
bptjm-29	470	14	in	in	ADP
bptjm-29	470	15	amyotrophic	amyotrophic	ADJ
bptjm-29	470	16	lateral	lateral	ADJ
bptjm-29	470	17	sclerosis	sclerosis	NOUN
bptjm-29	470	18	.	.	PUNCT
bptjm-29	471	1	n	n	PROPN
bptjm-29	471	2	engl	engl	PROPN
bptjm-29	471	3	j	j	PROPN
bptjm-29	471	4	med	me	VERB
bptjm-29	471	5	.	.	PUNCT
bptjm-29	472	1	1994;330(9):585	1994;330(9):585	NUM
bptjm-29	472	2	-	-	SYM
bptjm-29	472	3	591	591	NUM
bptjm-29	472	4	.	.	PUNCT
bptjm-29	472	5	doi:10.1056	doi:10.1056	PROPN
bptjm-29	472	6	/	/	SYM
bptjm-29	472	7	nejm199403033300901	nejm199403033300901	PROPN
bptjm-29	472	8	31	31	NUM
bptjm-29	472	9	.	.	PUNCT
bptjm-29	473	1	bellingham	bellingham	PROPN
bptjm-29	473	2	mc	mc	PROPN
bptjm-29	473	3	.	.	PUNCT
bptjm-29	474	1	a	a	DET
bptjm-29	474	2	review	review	NOUN
bptjm-29	474	3	of	of	ADP
bptjm-29	474	4	the	the	DET
bptjm-29	474	5	neural	neural	ADJ
bptjm-29	474	6	mechanisms	mechanism	NOUN
bptjm-29	474	7	of	of	ADP
bptjm-29	474	8	action	action	NOUN
bptjm-29	474	9	and	and	CCONJ
bptjm-29	474	10	clinical	clinical	ADJ
bptjm-29	474	11	e	e	NOUN
bptjm-29	474	12	�	�	NOUN
bptjm-29	474	13	ciency	ciency	NOUN
bptjm-29	474	14	of	of	ADP
bptjm-29	474	15	riluzole	riluzole	NOUN
bptjm-29	474	16	in	in	ADP
bptjm-29	474	17	treating	treat	VERB
bptjm-29	474	18	amyotrophic	amyotrophic	ADJ
bptjm-29	474	19	lateral	lateral	ADJ
bptjm-29	474	20	sclerosis	sclerosis	NOUN
bptjm-29	474	21	:	:	PUNCT
bptjm-29	474	22	what	what	PRON
bptjm-29	474	23	have	have	AUX
bptjm-29	474	24	we	we	PRON
bptjm-29	474	25	learned	learn	VERB
bptjm-29	474	26	in	in	ADP
bptjm-29	474	27	the	the	DET
bptjm-29	474	28	last	last	ADJ
bptjm-29	474	29	decade	decade	NOUN
bptjm-29	474	30	?	?	PUNCT
bptjm-29	475	1	cns	cns	PROPN
bptjm-29	475	2	neurosci	neurosci	PROPN
bptjm-29	475	3	ther	ther	ADV
bptjm-29	475	4	.	.	PUNCT
bptjm-29	476	1	2011;17(1):4	2011;17(1):4	NUM
bptjm-29	476	2	-	-	SYM
bptjm-29	476	3	31	31	NUM
bptjm-29	476	4	.	.	PUNCT
bptjm-29	477	1	doi:10.1111	doi:10.1111	ADJ
bptjm-29	477	2	/	/	SYM
bptjm-29	477	3	j.1755	j.1755	PROPN
bptjm-29	477	4	-	-	NOUN
bptjm-29	477	5	5949.2009.00116.x	5949.2009.00116.x	NUM
bptjm-29	477	6	32	32	NUM
bptjm-29	477	7	.	.	PUNCT
bptjm-29	478	1	e	e	X
bptjm-29	478	2	�	�	NOUN
bptjm-29	478	3	ects	ect	NOUN
bptjm-29	478	4	of	of	ADP
bptjm-29	478	5	benzothiazolamines	benzothiazolamine	NOUN
bptjm-29	478	6	on	on	ADP
bptjm-29	478	7	voltage	voltage	NOUN
bptjm-29	478	8	-	-	PUNCT
bptjm-29	478	9	gated	gate	VERB
bptjm-29	478	10	sodium	sodium	NOUN
bptjm-29	478	11	channels	channel	NOUN
bptjm-29	478	12	|	|	ADV
bptjm-29	478	13	springerlink	springerlink	VERB
bptjm-29	478	14	.	.	PUNCT
bptjm-29	479	1	accessed	access	VERB
bptjm-29	479	2	july	july	PROPN
bptjm-29	479	3	24	24	NUM
bptjm-29	479	4	,	,	PUNCT
bptjm-29	479	5	2022	2022	NUM
bptjm-29	479	6	.	.	PUNCT
bptjm-29	480	1	https://link.springer.com/chapter/10.1007/164_2017	https://link.springer.com/chapter/10.1007/164_2017	NOUN
bptjm-29	480	2	_	_	NOUN
bptjm-29	480	3	46	46	NUM
bptjm-29	480	4	33	33	NUM
bptjm-29	480	5	.	.	PUNCT
bptjm-29	481	1	hinchcli	hinchcli	PROPN
bptjm-29	481	2	�	�	PROPN
bptjm-29	481	3	e	e	PROPN
bptjm-29	481	4	m	m	PROPN
bptjm-29	481	5	,	,	PUNCT
bptjm-29	481	6	smith	smith	PROPN
bptjm-29	481	7	a.	a.	PROPN
bptjm-29	481	8	riluzole	riluzole	PROPN
bptjm-29	481	9	:	:	PUNCT
bptjm-29	481	10	real	real	ADJ
bptjm-29	481	11	-	-	PUNCT
bptjm-29	481	12	world	world	NOUN
bptjm-29	481	13	evidence	evidence	NOUN
bptjm-29	481	14	supports	support	VERB
bptjm-29	481	15	signi	signi	PROPN
bptjm-29	481	16	�	�	NOUN
bptjm-29	481	17	cant	cant	NOUN
bptjm-29	481	18	extension	extension	NOUN
bptjm-29	481	19	of	of	ADP
bptjm-29	481	20	median	median	PROPN
bptjm-29	481	21	berkeley	berkeley	PROPN
bptjm-29	481	22	pharma	pharma	PROPN
bptjm-29	481	23	tech	tech	NOUN
bptjm-29	481	24	journal	journal	NOUN
bptjm-29	481	25	of	of	ADP
bptjm-29	481	26	medicine	medicine	NOUN
bptjm-29	481	27	|	|	ADV
bptjm-29	481	28	100	100	NUM
bptjm-29	481	29	https://www.zotero.org/google-docs/?kaqxum	https://www.zotero.org/google-docs/?kaqxum	PROPN
bptjm-29	481	30	https://www.zotero.org/google-docs/?kaqxum	https://www.zotero.org/google-docs/?kaqxum	PROPN
bptjm-29	481	31	https://www.zotero.org/google-docs/?kaqxum	https://www.zotero.org/google-docs/?kaqxum	PROPN
bptjm-29	481	32	https://www.zotero.org/google-docs/?kaqxum	https://www.zotero.org/google-docs/?kaqxum	PROPN
bptjm-29	481	33	https://www.zotero.org/google-docs/?kaqxum	https://www.zotero.org/google-docs/?kaqxum	PROPN
bptjm-29	481	34	https://www.zotero.org/google-docs/?kaqxum	https://www.zotero.org/google-docs/?kaqxum	PROPN
bptjm-29	481	35	survival	survival	PROPN
bptjm-29	481	36	times	times	PROPN
bptjm-29	481	37	in	in	ADP
bptjm-29	481	38	patients	patient	NOUN
bptjm-29	481	39	with	with	ADP
bptjm-29	481	40	amyotrophic	amyotrophic	ADJ
bptjm-29	481	41	lateral	lateral	ADJ
bptjm-29	481	42	sclerosis	sclerosis	NOUN
bptjm-29	481	43	.	.	PUNCT
bptjm-29	482	1	degener	degener	NOUN
bptjm-29	482	2	neurol	neurol	PROPN
bptjm-29	482	3	neuromuscul	neuromuscul	PROPN
bptjm-29	482	4	dis	dis	PROPN
bptjm-29	482	5	.	.	PUNCT
bptjm-29	483	1	2017;7:61	2017;7:61	NUM
bptjm-29	483	2	-	-	PUNCT
bptjm-29	483	3	70	70	NUM
bptjm-29	483	4	.	.	PUNCT
bptjm-29	484	1	doi:10.2147	doi:10.2147	NOUN
bptjm-29	484	2	/	/	SYM
bptjm-29	484	3	dnnd.s135748	dnnd.s135748	NOUN
bptjm-29	484	4	34	34	NUM
bptjm-29	484	5	.	.	PUNCT
bptjm-29	485	1	andrews	andrews	PROPN
bptjm-29	485	2	ja	ja	PROPN
bptjm-29	485	3	,	,	PUNCT
bptjm-29	485	4	jackson	jackson	PROPN
bptjm-29	485	5	ce	ce	PROPN
bptjm-29	485	6	,	,	PUNCT
bptjm-29	485	7	heiman	heiman	NOUN
bptjm-29	485	8	-	-	PUNCT
bptjm-29	485	9	patterson	patterson	PROPN
bptjm-29	485	10	td	td	PROPN
bptjm-29	485	11	,	,	PUNCT
bptjm-29	485	12	bettica	bettica	PROPN
bptjm-29	485	13	p	p	PROPN
bptjm-29	485	14	,	,	PUNCT
bptjm-29	485	15	brooks	brooks	PROPN
bptjm-29	485	16	br	br	PROPN
bptjm-29	485	17	,	,	PUNCT
bptjm-29	485	18	pioro	pioro	PROPN
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bptjm-29	485	20	.	.	PUNCT
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bptjm-29	486	2	-	-	PUNCT
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bptjm-29	486	8	�	�	PROPN
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bptjm-29	486	10	in	in	ADP
bptjm-29	486	11	treating	treat	VERB
bptjm-29	486	12	amyotrophic	amyotrophic	ADJ
bptjm-29	486	13	lateral	lateral	ADJ
bptjm-29	486	14	sclerosis	sclerosis	NOUN
bptjm-29	486	15	.	.	PUNCT
bptjm-29	487	1	amyotroph	amyotroph	PROPN
bptjm-29	487	2	lateral	lateral	ADJ
bptjm-29	487	3	scler	scler	NOUN
bptjm-29	487	4	front	front	NOUN
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bptjm-29	487	6	.	.	PUNCT
bptjm-29	488	1	2020;21(7	2020;21(7	NUM
bptjm-29	488	2	-	-	PUNCT
bptjm-29	488	3	8):509	8):509	NUM
bptjm-29	488	4	-	-	SYM
bptjm-29	488	5	518	518	NUM
bptjm-29	488	6	.	.	PUNCT
bptjm-29	489	1	doi:10.1080/21678421.2020.1771734	doi:10.1080/21678421.2020.1771734	PROPN
bptjm-29	489	2	35	35	NUM
bptjm-29	489	3	.	.	PUNCT
bptjm-29	490	1	edaravone	edaravone	NOUN
bptjm-29	490	2	.	.	PUNCT
bptjm-29	491	1	the	the	DET
bptjm-29	491	2	als	als	NOUN
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bptjm-29	491	4	.	.	PUNCT
bptjm-29	492	1	accessed	access	VERB
bptjm-29	492	2	july	july	PROPN
bptjm-29	492	3	24	24	NUM
bptjm-29	492	4	,	,	PUNCT
bptjm-29	492	5	2022	2022	NUM
bptjm-29	492	6	.	.	PUNCT
bptjm-29	493	1	https://www.als.org/navigating-als/living-with-als/fda-a	https://www.als.org/navigating-als/living-with-als/fda-a	NOUN
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bptjm-29	493	3	-	-	PUNCT
bptjm-29	493	4	drugs	drug	NOUN
bptjm-29	493	5	/	/	SYM
bptjm-29	493	6	edaravone	edaravone	NOUN
bptjm-29	493	7	36	36	NUM
bptjm-29	493	8	.	.	PUNCT
bptjm-29	494	1	rantapää	rantapää	PROPN
bptjm-29	494	2	jl	jl	PROPN
bptjm-29	494	3	.	.	PUNCT
bptjm-29	495	1	a	a	DET
bptjm-29	495	2	comparison	comparison	NOUN
bptjm-29	495	3	between	between	ADP
bptjm-29	495	4	edaravone	edaravone	NOUN
bptjm-29	495	5	(	(	PUNCT
bptjm-29	495	6	radicavatm	radicavatm	NOUN
bptjm-29	495	7	)	)	PUNCT
bptjm-29	495	8	and	and	CCONJ
bptjm-29	495	9	riluzole	riluzole	NOUN
bptjm-29	495	10	regarding	regard	VERB
bptjm-29	495	11	indication	indication	NOUN
bptjm-29	495	12	and	and	CCONJ
bptjm-29	495	13	e	e	NOUN
bptjm-29	495	14	�	�	NOUN
bptjm-29	495	15	cacy	cacy	NOUN
bptjm-29	495	16	in	in	ADP
bptjm-29	495	17	als	als	NOUN
bptjm-29	495	18	patients	patient	NOUN
bptjm-29	495	19	.	.	PUNCT
bptjm-29	496	1	[	[	X
bptjm-29	496	2	master	master	NOUN
bptjm-29	496	3	thesis	thesis	NOUN
bptjm-29	496	4	]	]	X
bptjm-29	496	5	.	.	PUNCT
bptjm-29	497	1	umea	umea	ADJ
bptjm-29	497	2	,	,	PUNCT
bptjm-29	497	3	sweden	sweden	ADJ
bptjm-29	497	4	:	:	PUNCT
bptjm-29	497	5	umea	umea	ADJ
bptjm-29	497	6	university	university	NOUN
bptjm-29	497	7	;	;	PUNCT
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bptjm-29	497	9	.	.	PUNCT
bptjm-29	498	1	37	37	NUM
bptjm-29	498	2	.	.	PUNCT
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bptjm-29	498	4	tanabe	tanabe	PROPN
bptjm-29	498	5	pharma	pharma	PROPN
bptjm-29	498	6	development	development	PROPN
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bptjm-29	498	8	,	,	PUNCT
bptjm-29	498	9	inc	inc	PROPN
bptjm-29	498	10	.	.	PROPN
bptjm-29	498	11	a	a	DET
bptjm-29	498	12	phase	phase	NOUN
bptjm-29	498	13	3b	3b	NOUN
bptjm-29	498	14	,	,	PUNCT
bptjm-29	498	15	multicenter	multicenter	NOUN
bptjm-29	498	16	,	,	PUNCT
bptjm-29	498	17	randomized	randomize	VERB
bptjm-29	498	18	,	,	PUNCT
bptjm-29	498	19	double	double	ADJ
bptjm-29	498	20	-	-	PUNCT
bptjm-29	498	21	blind	blind	ADJ
bptjm-29	498	22	study	study	NOUN
bptjm-29	498	23	to	to	PART
bptjm-29	498	24	evaluate	evaluate	VERB
bptjm-29	498	25	efficacy	efficacy	NOUN
bptjm-29	498	26	and	and	CCONJ
bptjm-29	498	27	safety	safety	NOUN
bptjm-29	498	28	of	of	ADP
bptjm-29	498	29	oral	oral	ADJ
bptjm-29	498	30	edaravone	edaravone	NOUN
bptjm-29	498	31	administered	administer	VERB
bptjm-29	498	32	for	for	ADP
bptjm-29	498	33	a	a	DET
bptjm-29	498	34	period	period	NOUN
bptjm-29	498	35	of	of	ADP
bptjm-29	498	36	48	48	NUM
bptjm-29	498	37	weeks	week	NOUN
bptjm-29	498	38	in	in	ADP
bptjm-29	498	39	subjects	subject	NOUN
bptjm-29	498	40	with	with	ADP
bptjm-29	498	41	amyotrophic	amyotrophic	ADJ
bptjm-29	498	42	lateral	lateral	ADJ
bptjm-29	498	43	sclerosis	sclerosis	NOUN
bptjm-29	498	44	(	(	PUNCT
bptjm-29	498	45	als	als	NOUN
bptjm-29	498	46	)	)	PUNCT
bptjm-29	498	47	.	.	PUNCT
bptjm-29	499	1	clinicaltrials.gov	clinicaltrials.gov	NOUN
bptjm-29	499	2	;	;	PUNCT
bptjm-29	499	3	2022	2022	NUM
bptjm-29	499	4	.	.	PUNCT
bptjm-29	499	5	accessed	access	VERB
bptjm-29	499	6	july	july	PROPN
bptjm-29	499	7	21	21	NUM
bptjm-29	499	8	,	,	PUNCT
bptjm-29	499	9	2022	2022	NUM
bptjm-29	499	10	.	.	PUNCT
bptjm-29	500	1	https://clinicaltrials.gov/ct2/show/study/nct0456908	https://clinicaltrials.gov/ct2/show/study/nct0456908	ADP
bptjm-29	500	2	4	4	NUM
bptjm-29	500	3	38	38	NUM
bptjm-29	500	4	.	.	PUNCT
bptjm-29	501	1	two	two	NUM
bptjm-29	501	2	decades	decade	NOUN
bptjm-29	501	3	-	-	PUNCT
bptjm-29	501	4	long	long	ADJ
bptjm-29	501	5	journey	journey	NOUN
bptjm-29	501	6	from	from	ADP
bptjm-29	501	7	riluzole	riluzole	NOUN
bptjm-29	501	8	to	to	ADP
bptjm-29	501	9	edaravone	edaravone	NOUN
bptjm-29	501	10	:	:	PUNCT
bptjm-29	501	11	revisiting	revisit	VERB
bptjm-29	501	12	the	the	DET
bptjm-29	501	13	clinical	clinical	ADJ
bptjm-29	501	14	pharmacokinetics	pharmacokinetic	NOUN
bptjm-29	501	15	of	of	ADP
bptjm-29	501	16	the	the	DET
bptjm-29	501	17	only	only	ADJ
bptjm-29	501	18	two	two	NUM
bptjm-29	501	19	amyotrophic	amyotrophic	ADJ
bptjm-29	501	20	lateral	lateral	ADJ
bptjm-29	501	21	sclerosis	sclerosis	NOUN
bptjm-29	501	22	therapeutics	therapeutic	NOUN
bptjm-29	501	23	|	|	ADV
bptjm-29	501	24	springerlink	springerlink	VERB
bptjm-29	501	25	.	.	PUNCT
bptjm-29	502	1	accessed	access	VERB
bptjm-29	502	2	july	july	PROPN
bptjm-29	502	3	24	24	NUM
bptjm-29	502	4	,	,	PUNCT
bptjm-29	502	5	2022	2022	NUM
bptjm-29	502	6	.	.	PUNCT
bptjm-29	503	1	https://link.springer.com/article/10.1007/s40262-018-0	https://link.springer.com/article/10.1007/s40262-018-0	NOUN
bptjm-29	503	2	655	655	NUM
bptjm-29	503	3	-	-	SYM
bptjm-29	503	4	4	4	NUM
bptjm-29	503	5	39	39	NUM
bptjm-29	503	6	.	.	PUNCT
bptjm-29	504	1	safety	safety	NOUN
bptjm-29	504	2	and	and	CCONJ
bptjm-29	504	3	e	e	NOUN
bptjm-29	504	4	�	�	NOUN
bptjm-29	504	5	ectiveness	ectiveness	NOUN
bptjm-29	504	6	of	of	ADP
bptjm-29	504	7	long	long	ADJ
bptjm-29	504	8	-	-	PUNCT
bptjm-29	504	9	term	term	NOUN
bptjm-29	504	10	intravenous	intravenous	ADJ
bptjm-29	504	11	administration	administration	NOUN
bptjm-29	504	12	of	of	ADP
bptjm-29	504	13	edaravone	edaravone	NOUN
bptjm-29	504	14	for	for	ADP
bptjm-29	504	15	treatment	treatment	NOUN
bptjm-29	504	16	of	of	ADP
bptjm-29	504	17	patients	patient	NOUN
bptjm-29	504	18	with	with	ADP
bptjm-29	504	19	amyotrophic	amyotrophic	ADJ
bptjm-29	504	20	lateral	lateral	ADJ
bptjm-29	504	21	sclerosis	sclerosis	NOUN
bptjm-29	504	22	|	|	ADP
bptjm-29	504	23	amyotrophic	amyotrophic	ADJ
bptjm-29	504	24	lateral	lateral	ADJ
bptjm-29	504	25	sclerosis	sclerosis	NOUN
bptjm-29	504	26	|	|	ADV
bptjm-29	504	27	jama	jama	NOUN
bptjm-29	504	28	neurology	neurology	NOUN
bptjm-29	504	29	|	|	ADV
bptjm-29	504	30	jama	jama	PROPN
bptjm-29	504	31	network	network	NOUN
bptjm-29	504	32	.	.	PUNCT
bptjm-29	505	1	accessed	access	VERB
bptjm-29	505	2	july	july	PROPN
bptjm-29	505	3	24	24	NUM
bptjm-29	505	4	,	,	PUNCT
bptjm-29	505	5	2022	2022	NUM
bptjm-29	505	6	.	.	PUNCT
bptjm-29	506	1	https://jamanetwork.com/journals/jamaneurology/artic	https://jamanetwork.com/journals/jamaneurology/artic	PROPN
bptjm-29	506	2	le	le	X
bptjm-29	506	3	-	-	PUNCT
bptjm-29	506	4	abstract/2787473	abstract/2787473	ADJ
bptjm-29	506	5	40	40	NUM
bptjm-29	506	6	.	.	PUNCT
bptjm-29	506	7	trial	trial	NOUN
bptjm-29	506	8	of	of	ADP
bptjm-29	506	9	sodium	sodium	NOUN
bptjm-29	506	10	phenylbutyrate	phenylbutyrate	ADJ
bptjm-29	506	11	–	–	PUNCT
bptjm-29	506	12	taurursodiol	taurursodiol	NOUN
bptjm-29	506	13	for	for	ADP
bptjm-29	506	14	amyotrophic	amyotrophic	ADJ
bptjm-29	506	15	lateral	lateral	ADJ
bptjm-29	506	16	sclerosis	sclerosis	NOUN
bptjm-29	506	17	|	|	PROPN
bptjm-29	506	18	nejm	nejm	PROPN
bptjm-29	506	19	.	.	PUNCT
bptjm-29	507	1	accessed	access	VERB
bptjm-29	507	2	october	october	PROPN
bptjm-29	507	3	12	12	NUM
bptjm-29	507	4	,	,	PUNCT
bptjm-29	507	5	2022	2022	NUM
bptjm-29	507	6	.	.	PUNCT
bptjm-29	508	1	https://www.nejm.org/doi/full/10.1056/nejmoa1916	https://www.nejm.org/doi/full/10.1056/nejmoa1916	PROPN
bptjm-29	508	2	945	945	NUM
bptjm-29	508	3	41	41	NUM
bptjm-29	508	4	.	.	PUNCT
bptjm-29	509	1	als	als	NOUN
bptjm-29	509	2	drug	drug	NOUN
bptjm-29	509	3	approved	approve	VERB
bptjm-29	509	4	by	by	ADP
bptjm-29	509	5	fda	fda	PROPN
bptjm-29	509	6	in	in	ADP
bptjm-29	509	7	closely	closely	ADV
bptjm-29	509	8	watched	watch	VERB
bptjm-29	509	9	decision	decision	NOUN
bptjm-29	509	10	,	,	PUNCT
bptjm-29	509	11	marking	mark	VERB
bptjm-29	509	12	win	win	NOUN
bptjm-29	509	13	for	for	ADP
bptjm-29	509	14	patients	patient	NOUN
bptjm-29	509	15	,	,	PUNCT
bptjm-29	509	16	developer	developer	NOUN
bptjm-29	509	17	|	|	NOUN
bptjm-29	509	18	biopharma	biopharma	NOUN
bptjm-29	509	19	dive	dive	NOUN
bptjm-29	509	20	.	.	PUNCT
bptjm-29	510	1	accessed	access	VERB
bptjm-29	510	2	october	october	PROPN
bptjm-29	510	3	12	12	NUM
bptjm-29	510	4	,	,	PUNCT
bptjm-29	510	5	2022	2022	NUM
bptjm-29	510	6	.	.	PUNCT
bptjm-29	511	1	https://www.biopharmadive.com/news/amylyx-fda-appr	https://www.biopharmadive.com/news/amylyx-fda-appr	NOUN
bptjm-29	511	2	oval	oval	NOUN
bptjm-29	511	3	-	-	PUNCT
bptjm-29	511	4	als	al	NOUN
bptjm-29	511	5	-	-	PUNCT
bptjm-29	511	6	drug	drug	NOUN
bptjm-29	511	7	-	-	PUNCT
bptjm-29	511	8	relyvrio/632592/	relyvrio/632592/	NOUN
bptjm-29	511	9	42	42	NUM
bptjm-29	511	10	.	.	PUNCT
bptjm-29	512	1	trial	trial	NOUN
bptjm-29	512	2	of	of	ADP
bptjm-29	512	3	sodium	sodium	NOUN
bptjm-29	512	4	phenylbutyrate	phenylbutyrate	ADJ
bptjm-29	512	5	–	–	PUNCT
bptjm-29	512	6	taurursodiol	taurursodiol	NOUN
bptjm-29	512	7	for	for	ADP
bptjm-29	512	8	amyotrophic	amyotrophic	ADJ
bptjm-29	512	9	lateral	lateral	ADJ
bptjm-29	512	10	sclerosis	sclerosis	NOUN
bptjm-29	512	11	|	|	PROPN
bptjm-29	512	12	nejm	nejm	PROPN
bptjm-29	512	13	.	.	PUNCT
bptjm-29	513	1	accessed	access	VERB
bptjm-29	513	2	july	july	PROPN
bptjm-29	513	3	24	24	NUM
bptjm-29	513	4	,	,	PUNCT
bptjm-29	513	5	2022	2022	NUM
bptjm-29	513	6	.	.	PUNCT
bptjm-29	514	1	https://www.nejm.org/doi/10.1056/nejmoa1916945	https://www.nejm.org/doi/10.1056/nejmoa1916945	PROPN
bptjm-29	514	2	43	43	NUM
bptjm-29	514	3	.	.	PUNCT
bptjm-29	515	1	izrael	izrael	PROPN
bptjm-29	515	2	m	m	PROPN
bptjm-29	515	3	,	,	PUNCT
bptjm-29	515	4	slutsky	slutsky	PROPN
bptjm-29	515	5	sg	sg	PROPN
bptjm-29	515	6	,	,	PUNCT
bptjm-29	515	7	revel	revel	ADJ
bptjm-29	515	8	m.	m.	NOUN
bptjm-29	515	9	rising	rise	VERB
bptjm-29	515	10	stars	star	NOUN
bptjm-29	515	11	:	:	PUNCT
bptjm-29	515	12	astrocytes	astrocyte	NOUN
bptjm-29	515	13	as	as	ADP
bptjm-29	515	14	a	a	DET
bptjm-29	515	15	therapeutic	therapeutic	ADJ
bptjm-29	515	16	target	target	NOUN
bptjm-29	515	17	for	for	ADP
bptjm-29	515	18	als	als	NOUN
bptjm-29	515	19	disease	disease	NOUN
bptjm-29	515	20	.	.	PUNCT
bptjm-29	516	1	front	front	ADJ
bptjm-29	516	2	neurosci	neurosci	PROPN
bptjm-29	516	3	.	.	PUNCT
bptjm-29	517	1	2020;14:824	2020;14:824	X
bptjm-29	517	2	.	.	PUNCT
bptjm-29	517	3	doi:10.3389	doi:10.3389	PROPN
bptjm-29	517	4	/	/	SYM
bptjm-29	517	5	fnins.2020.00824	fnins.2020.00824	NOUN
bptjm-29	517	6	44	44	NUM
bptjm-29	517	7	.	.	PUNCT
bptjm-29	518	1	cirm_2.0	cirm_2.0	PROPN
bptjm-29	518	2	.	.	PUNCT
bptjm-29	519	1	cns10	cns10	ADJ
bptjm-29	519	2	-	-	PUNCT
bptjm-29	519	3	npc	npc	NOUN
bptjm-29	519	4	-	-	PUNCT
bptjm-29	519	5	gdnf	gdnf	NOUN
bptjm-29	519	6	delivered	deliver	VERB
bptjm-29	519	7	into	into	ADP
bptjm-29	519	8	the	the	DET
bptjm-29	519	9	motor	motor	NOUN
bptjm-29	519	10	cortex	cortex	NOUN
bptjm-29	519	11	for	for	ADP
bptjm-29	519	12	the	the	DET
bptjm-29	519	13	treatment	treatment	NOUN
bptjm-29	519	14	of	of	ADP
bptjm-29	519	15	als	al	NOUN
bptjm-29	519	16	.	.	PUNCT
bptjm-29	520	1	california	california	PROPN
bptjm-29	520	2	’s	’s	PART
bptjm-29	520	3	stem	stem	NOUN
bptjm-29	520	4	cell	cell	NOUN
bptjm-29	520	5	agency	agency	NOUN
bptjm-29	520	6	.	.	PUNCT
bptjm-29	521	1	published	publish	VERB
bptjm-29	521	2	july	july	PROPN
bptjm-29	521	3	23	23	NUM
bptjm-29	521	4	,	,	PUNCT
bptjm-29	521	5	2022	2022	NUM
bptjm-29	521	6	.	.	PUNCT
bptjm-29	522	1	accessed	access	VERB
bptjm-29	522	2	july	july	PROPN
bptjm-29	522	3	24	24	NUM
bptjm-29	522	4	,	,	PUNCT
bptjm-29	522	5	2022	2022	NUM
bptjm-29	522	6	.	.	PUNCT
bptjm-29	523	1	https://www.cirm.ca.gov/our-progress/awards/cns10-np	https://www.cirm.ca.gov/our-progress/awards/cns10-np	NOUN
bptjm-29	523	2	c	c	NOUN
bptjm-29	523	3	-	-	PUNCT
bptjm-29	523	4	gdnf	gdnf	NOUN
bptjm-29	523	5	-	-	PUNCT
bptjm-29	523	6	delivered	deliver	VERB
bptjm-29	523	7	-	-	PUNCT
bptjm-29	523	8	motor	motor	NOUN
bptjm-29	523	9	-	-	PUNCT
bptjm-29	523	10	cortex	cortex	NOUN
bptjm-29	523	11	-	-	PUNCT
bptjm-29	523	12	treatment	treatment	NOUN
bptjm-29	523	13	-	-	PUNCT
bptjm-29	523	14	als	als	NOUN
bptjm-29	523	15	45	45	NUM
bptjm-29	523	16	.	.	PUNCT
bptjm-29	524	1	the	the	DET
bptjm-29	524	2	multi	multi	ADJ
bptjm-29	524	3	-	-	ADJ
bptjm-29	524	4	dimensional	dimensional	ADJ
bptjm-29	524	5	roles	role	NOUN
bptjm-29	524	6	of	of	ADP
bptjm-29	524	7	astrocytes	astrocyte	NOUN
bptjm-29	524	8	in	in	ADP
bptjm-29	524	9	als	als	NOUN
bptjm-29	524	10	sciencedirect	sciencedirect	PROPN
bptjm-29	524	11	.	.	PUNCT
bptjm-29	524	12	accessed	access	VERB
bptjm-29	524	13	july	july	PROPN
bptjm-29	524	14	24	24	NUM
bptjm-29	524	15	,	,	PUNCT
bptjm-29	524	16	2022	2022	NUM
bptjm-29	524	17	.	.	PUNCT
bptjm-29	525	1	https://www.sciencedirect.com/science/article/pii/s016	https://www.sciencedirect.com/science/article/pii/s016	PROPN
bptjm-29	525	2	8010217305473#	8010217305473#	PROPN
bptjm-29	525	3	�	�	PROPN
bptjm-29	525	4	g0015	g0015	PROPN
bptjm-29	525	5	46	46	NUM
bptjm-29	525	6	.	.	PUNCT
bptjm-29	525	7	mao	mao	PROPN
bptjm-29	526	1	as	as	ADP
bptjm-29	526	2	,	,	PUNCT
bptjm-29	526	3	mooney	mooney	PROPN
bptjm-29	526	4	dj	dj	PROPN
bptjm-29	526	5	.	.	PUNCT
bptjm-29	526	6	regenerative	regenerative	ADJ
bptjm-29	526	7	medicine	medicine	NOUN
bptjm-29	526	8	:	:	PUNCT
bptjm-29	526	9	current	current	ADJ
bptjm-29	526	10	therapies	therapy	NOUN
bptjm-29	526	11	and	and	CCONJ
bptjm-29	526	12	future	future	ADJ
bptjm-29	526	13	directions	direction	NOUN
bptjm-29	526	14	.	.	PUNCT
bptjm-29	527	1	proc	proc	PROPN
bptjm-29	527	2	natl	natl	PROPN
bptjm-29	527	3	acad	acad	PROPN
bptjm-29	527	4	sci	sci	PROPN
bptjm-29	527	5	u	u	PROPN
bptjm-29	527	6	s	s	NOUN
bptjm-29	527	7	a.	a.	NOUN
bptjm-29	527	8	2015;112(47):14452	2015;112(47):14452	PROPN
bptjm-29	527	9	-	-	SYM
bptjm-29	527	10	14459	14459	NUM
bptjm-29	527	11	.	.	PUNCT
bptjm-29	528	1	doi:10.1073	doi:10.1073	NOUN
bptjm-29	528	2	/	/	PUNCT
bptjm-29	529	1	pnas.1508520112	pnas.1508520112	PROPN
bptjm-29	529	2	47	47	NUM
bptjm-29	529	3	.	.	PUNCT
bptjm-29	530	1	bacakova	bacakova	PROPN
bptjm-29	531	1	l	l	PROPN
bptjm-29	531	2	,	,	PUNCT
bptjm-29	531	3	zarubova	zarubova	PROPN
bptjm-29	531	4	j	j	PROPN
bptjm-29	531	5	,	,	PUNCT
bptjm-29	531	6	travnickova	travnickova	PROPN
bptjm-29	531	7	m	m	PROPN
bptjm-29	531	8	,	,	PUNCT
bptjm-29	531	9	et	et	PROPN
bptjm-29	531	10	al	al	PROPN
bptjm-29	531	11	.	.	PROPN
bptjm-29	531	12	stem	stem	NOUN
bptjm-29	531	13	cells	cell	NOUN
bptjm-29	531	14	:	:	PUNCT
bptjm-29	531	15	their	their	PRON
bptjm-29	531	16	source	source	NOUN
bptjm-29	531	17	,	,	PUNCT
bptjm-29	531	18	potency	potency	NOUN
bptjm-29	531	19	and	and	CCONJ
bptjm-29	531	20	use	use	NOUN
bptjm-29	531	21	in	in	ADP
bptjm-29	531	22	regenerative	regenerative	ADJ
bptjm-29	531	23	berkeley	berkeley	PROPN
bptjm-29	531	24	pharma	pharma	PROPN
bptjm-29	531	25	tech	tech	NOUN
bptjm-29	531	26	journal	journal	NOUN
bptjm-29	531	27	of	of	ADP
bptjm-29	531	28	medicine	medicine	NOUN
bptjm-29	531	29	|	|	ADV
bptjm-29	531	30	101	101	NUM
bptjm-29	531	31	therapies	therapy	NOUN
bptjm-29	531	32	with	with	ADP
bptjm-29	531	33	focus	focus	NOUN
bptjm-29	531	34	on	on	ADP
bptjm-29	531	35	adipose	adipose	NOUN
bptjm-29	531	36	-	-	PUNCT
bptjm-29	531	37	derived	derive	VERB
bptjm-29	531	38	stem	stem	NOUN
bptjm-29	531	39	cells	cell	NOUN
bptjm-29	531	40	a	a	DET
bptjm-29	531	41	review	review	NOUN
bptjm-29	531	42	.	.	PUNCT
bptjm-29	532	1	biotechnol	biotechnol	PROPN
bptjm-29	532	2	adv	adv	PROPN
bptjm-29	532	3	.	.	PUNCT
bptjm-29	533	1	2018;36(4):1111	2018;36(4):1111	PROPN
bptjm-29	533	2	-	-	SYM
bptjm-29	533	3	1126	1126	NUM
bptjm-29	533	4	.	.	PUNCT
bptjm-29	534	1	doi:10.1016	doi:10.1016	PROPN
bptjm-29	534	2	/	/	SYM
bptjm-29	534	3	j.biotechadv.2018.03.011	j.biotechadv.2018.03.011	PROPN
bptjm-29	534	4	48	48	NUM
bptjm-29	534	5	.	.	PUNCT
bptjm-29	535	1	kolios	kolio	VERB
bptjm-29	535	2	g	g	NOUN
bptjm-29	535	3	,	,	PUNCT
bptjm-29	535	4	moodley	moodley	PROPN
bptjm-29	535	5	y.	y.	PROPN
bptjm-29	535	6	introduction	introduction	NOUN
bptjm-29	535	7	to	to	PART
bptjm-29	535	8	stem	stem	VERB
bptjm-29	535	9	cells	cell	NOUN
bptjm-29	535	10	and	and	CCONJ
bptjm-29	535	11	regenerative	regenerative	ADJ
bptjm-29	535	12	medicine	medicine	NOUN
bptjm-29	535	13	.	.	PUNCT
bptjm-29	536	1	respiration	respiration	NOUN
bptjm-29	536	2	.	.	PUNCT
bptjm-29	537	1	2013;85(1):3	2013;85(1):3	NUM
bptjm-29	537	2	-	-	SYM
bptjm-29	537	3	10	10	NUM
bptjm-29	537	4	.	.	PUNCT
bptjm-29	538	1	doi:10.1159/000345615	doi:10.1159/000345615	NOUN
bptjm-29	538	2	49	49	NUM
bptjm-29	538	3	.	.	PUNCT
bptjm-29	538	4	gurusamy	gurusamy	PROPN
bptjm-29	538	5	n	n	CCONJ
bptjm-29	538	6	,	,	PUNCT
bptjm-29	538	7	alsayari	alsayari	X
bptjm-29	538	8	a	a	X
bptjm-29	538	9	,	,	PUNCT
bptjm-29	538	10	rajasingh	rajasingh	NOUN
bptjm-29	538	11	s	s	PROPN
bptjm-29	538	12	,	,	PUNCT
bptjm-29	538	13	rajasingh	rajasingh	PROPN
bptjm-29	538	14	j.	j.	PROPN
bptjm-29	538	15	adult	adult	PROPN
bptjm-29	538	16	stem	stem	NOUN
bptjm-29	538	17	cells	cell	NOUN
bptjm-29	538	18	for	for	ADP
bptjm-29	538	19	regenerative	regenerative	ADJ
bptjm-29	538	20	therapy	therapy	NOUN
bptjm-29	538	21	.	.	PUNCT
bptjm-29	539	1	prog	prog	NOUN
bptjm-29	539	2	mol	mol	ADP
bptjm-29	539	3	biol	biol	PROPN
bptjm-29	539	4	transl	transl	PROPN
bptjm-29	539	5	sci	sci	PROPN
bptjm-29	539	6	.	.	PUNCT
bptjm-29	540	1	2018;160:1	2018;160:1	PROPN
bptjm-29	540	2	-	-	SYM
bptjm-29	540	3	22	22	NUM
bptjm-29	540	4	.	.	PUNCT
bptjm-29	541	1	doi:10.1016	doi:10.1016	PROPN
bptjm-29	541	2	/	/	SYM
bptjm-29	541	3	bs.pmbts.2018.07.009	bs.pmbts.2018.07.009	PROPN
bptjm-29	541	4	50	50	NUM
bptjm-29	541	5	.	.	PUNCT
bptjm-29	542	1	cable	cable	PROPN
bptjm-29	542	2	j	j	PROPN
bptjm-29	542	3	,	,	PUNCT
bptjm-29	542	4	fuchs	fuchs	PROPN
bptjm-29	542	5	e	e	PROPN
bptjm-29	542	6	,	,	PUNCT
bptjm-29	542	7	weissman	weissman	PROPN
bptjm-29	542	8	i	i	PROPN
bptjm-29	542	9	,	,	PUNCT
bptjm-29	542	10	et	et	PROPN
bptjm-29	542	11	al	al	PROPN
bptjm-29	542	12	.	.	PUNCT
bptjm-29	542	13	adult	adult	NOUN
bptjm-29	542	14	stem	stem	NOUN
bptjm-29	542	15	cells	cell	NOUN
bptjm-29	542	16	and	and	CCONJ
bptjm-29	542	17	regenerative	regenerative	ADJ
bptjm-29	542	18	medicine	medicine	NOUN
bptjm-29	542	19	-	-	PUNCT
bptjm-29	542	20	a	a	DET
bptjm-29	542	21	symposium	symposium	NOUN
bptjm-29	542	22	report	report	NOUN
bptjm-29	542	23	.	.	PUNCT
bptjm-29	543	1	ann	ann	PROPN
bptjm-29	543	2	n	n	PROPN
bptjm-29	543	3	y	y	PROPN
bptjm-29	543	4	acad	acad	PROPN
bptjm-29	543	5	sci	sci	PROPN
bptjm-29	543	6	.	.	PUNCT
bptjm-29	544	1	2020;1462(1):27	2020;1462(1):27	NUM
bptjm-29	544	2	-	-	SYM
bptjm-29	544	3	36	36	NUM
bptjm-29	544	4	.	.	PUNCT
bptjm-29	545	1	doi:10.1111	doi:10.1111	PROPN
bptjm-29	545	2	/	/	SYM
bptjm-29	545	3	nyas.14243	nyas.14243	PROPN
bptjm-29	545	4	51	51	NUM
bptjm-29	545	5	.	.	PUNCT
bptjm-29	546	1	agrawal	agrawal	PROPN
bptjm-29	546	2	m	m	PROPN
bptjm-29	546	3	,	,	PUNCT
bptjm-29	546	4	alexander	alexander	PROPN
bptjm-29	546	5	a	a	PROPN
bptjm-29	546	6	,	,	PUNCT
bptjm-29	546	7	khan	khan	PROPN
bptjm-29	546	8	j	j	PROPN
bptjm-29	546	9	,	,	PUNCT
bptjm-29	546	10	et	et	PROPN
bptjm-29	546	11	al	al	PROPN
bptjm-29	546	12	.	.	PUNCT
bptjm-29	547	1	recent	recent	ADJ
bptjm-29	547	2	biomedical	biomedical	ADJ
bptjm-29	547	3	applications	application	NOUN
bptjm-29	547	4	on	on	ADP
bptjm-29	547	5	stem	stem	NOUN
bptjm-29	547	6	cell	cell	NOUN
bptjm-29	547	7	therapy	therapy	NOUN
bptjm-29	547	8	:	:	PUNCT
bptjm-29	547	9	a	a	DET
bptjm-29	547	10	brief	brief	ADJ
bptjm-29	547	11	overview	overview	NOUN
bptjm-29	547	12	.	.	PUNCT
bptjm-29	548	1	curr	curr	PROPN
bptjm-29	548	2	stem	stem	NOUN
bptjm-29	548	3	cell	cell	NOUN
bptjm-29	548	4	res	re	NOUN
bptjm-29	548	5	ther	ther	ADV
bptjm-29	548	6	.	.	PUNCT
bptjm-29	549	1	2019;14(2):127	2019;14(2):127	NUM
bptjm-29	549	2	-	-	SYM
bptjm-29	549	3	136	136	NUM
bptjm-29	549	4	.	.	PUNCT
bptjm-29	549	5	doi:10.2174/1574888x13666181002161700	doi:10.2174/1574888x13666181002161700	ADP
bptjm-29	549	6	52	52	NUM
bptjm-29	549	7	.	.	PUNCT
bptjm-29	550	1	lo	lo	PROPN
bptjm-29	550	2	b	b	PROPN
bptjm-29	550	3	,	,	PUNCT
bptjm-29	550	4	parham	parham	PROPN
bptjm-29	550	5	l.	l.	PROPN
bptjm-29	550	6	ethical	ethical	PROPN
bptjm-29	550	7	issues	issue	NOUN
bptjm-29	550	8	in	in	ADP
bptjm-29	550	9	stem	stem	NOUN
bptjm-29	550	10	cell	cell	NOUN
bptjm-29	550	11	research	research	NOUN
bptjm-29	550	12	.	.	PUNCT
bptjm-29	551	1	endocr	endocr	PROPN
bptjm-29	551	2	rev	rev	PROPN
bptjm-29	551	3	.	.	PUNCT
bptjm-29	552	1	2009;30(3):204	2009;30(3):204	NUM
bptjm-29	552	2	-	-	PUNCT
bptjm-29	552	3	213	213	NUM
bptjm-29	552	4	.	.	PUNCT
bptjm-29	553	1	doi:10.1210	doi:10.1210	PROPN
bptjm-29	553	2	/	/	SYM
bptjm-29	553	3	er.2008	er.2008	NOUN
bptjm-29	553	4	-	-	PUNCT
bptjm-29	553	5	0031	0031	NUM
bptjm-29	553	6	53	53	NUM
bptjm-29	553	7	.	.	PUNCT
bptjm-29	554	1	shi	shi	PROPN
bptjm-29	554	2	y	y	PROPN
bptjm-29	554	3	,	,	PUNCT
bptjm-29	554	4	inoue	inoue	PROPN
bptjm-29	554	5	h	h	PROPN
bptjm-29	554	6	,	,	PUNCT
bptjm-29	554	7	wu	wu	PROPN
bptjm-29	554	8	jc	jc	PROPN
bptjm-29	554	9	,	,	PUNCT
bptjm-29	554	10	yamanaka	yamanaka	PROPN
bptjm-29	554	11	s.	s.	PROPN
bptjm-29	554	12	induced	induce	VERB
bptjm-29	554	13	pluripotent	pluripotent	ADJ
bptjm-29	554	14	stem	stem	NOUN
bptjm-29	554	15	cell	cell	NOUN
bptjm-29	554	16	technology	technology	NOUN
bptjm-29	554	17	:	:	PUNCT
bptjm-29	554	18	a	a	DET
bptjm-29	554	19	decade	decade	NOUN
bptjm-29	554	20	of	of	ADP
bptjm-29	554	21	progress	progress	NOUN
bptjm-29	554	22	.	.	PUNCT
bptjm-29	555	1	nat	nat	PROPN
bptjm-29	555	2	rev	rev	VERB
bptjm-29	555	3	drug	drug	NOUN
bptjm-29	555	4	discov	discov	NOUN
bptjm-29	555	5	.	.	PUNCT
bptjm-29	556	1	2017;16(2):115	2017;16(2):115	NUM
bptjm-29	556	2	-	-	PUNCT
bptjm-29	556	3	130	130	NUM
bptjm-29	556	4	.	.	PUNCT
bptjm-29	557	1	doi:10.1038	doi:10.1038	NOUN
bptjm-29	557	2	/	/	SYM
bptjm-29	557	3	nrd.2016.245	nrd.2016.245	PROPN
bptjm-29	557	4	54	54	NUM
bptjm-29	557	5	.	.	PUNCT
bptjm-29	558	1	salem	salem	PROPN
bptjm-29	558	2	hk	hk	PROPN
bptjm-29	558	3	,	,	PUNCT
bptjm-29	558	4	thiemermann	thiemermann	PROPN
bptjm-29	558	5	c.	c.	PROPN
bptjm-29	558	6	mesenchymal	mesenchymal	ADJ
bptjm-29	558	7	stromal	stromal	ADJ
bptjm-29	558	8	cells	cell	NOUN
bptjm-29	558	9	:	:	PUNCT
bptjm-29	558	10	current	current	ADJ
bptjm-29	558	11	understanding	understanding	NOUN
bptjm-29	558	12	and	and	CCONJ
bptjm-29	558	13	clinical	clinical	ADJ
bptjm-29	558	14	status	status	NOUN
bptjm-29	558	15	.	.	PUNCT
bptjm-29	559	1	stem	stem	NOUN
bptjm-29	559	2	cells	cell	NOUN
bptjm-29	559	3	dayt	dayt	VERB
bptjm-29	559	4	ohio	ohio	PROPN
bptjm-29	559	5	.	.	PUNCT
bptjm-29	560	1	2010;28(3):585	2010;28(3):585	NUM
bptjm-29	560	2	-	-	SYM
bptjm-29	560	3	596	596	NUM
bptjm-29	560	4	.	.	PUNCT
bptjm-29	561	1	doi:10.1002	doi:10.1002	NOUN
bptjm-29	561	2	/	/	SYM
bptjm-29	561	3	stem.269	stem.269	ADV
bptjm-29	561	4	55	55	NUM
bptjm-29	561	5	.	.	PUNCT
bptjm-29	562	1	stem	stem	NOUN
bptjm-29	562	2	cell	cell	NOUN
bptjm-29	562	3	therapy	therapy	NOUN
bptjm-29	562	4	:	:	PUNCT
bptjm-29	562	5	a	a	DET
bptjm-29	562	6	look	look	NOUN
bptjm-29	562	7	at	at	ADP
bptjm-29	562	8	current	current	ADJ
bptjm-29	562	9	research	research	NOUN
bptjm-29	562	10	,	,	PUNCT
bptjm-29	562	11	regulations	regulation	NOUN
bptjm-29	562	12	,	,	PUNCT
bptjm-29	562	13	and	and	CCONJ
bptjm-29	562	14	remaining	remain	VERB
bptjm-29	562	15	hurdles	hurdle	NOUN
bptjm-29	562	16	pmc	pmc	PROPN
bptjm-29	562	17	.	.	PUNCT
bptjm-29	563	1	accessed	access	VERB
bptjm-29	563	2	july	july	PROPN
bptjm-29	563	3	24	24	NUM
bptjm-29	563	4	,	,	PUNCT
bptjm-29	563	5	2022	2022	NUM
bptjm-29	563	6	.	.	PUNCT
bptjm-29	564	1	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4264	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4264	VERB
bptjm-29	564	2	671/	671/	NUM
bptjm-29	564	3	56	56	NUM
bptjm-29	564	4	.	.	PUNCT
bptjm-29	565	1	vasanthan	vasanthan	PROPN
bptjm-29	565	2	j	j	PROPN
bptjm-29	565	3	,	,	PUNCT
bptjm-29	565	4	gurusamy	gurusamy	PROPN
bptjm-29	565	5	n	n	CCONJ
bptjm-29	565	6	,	,	PUNCT
bptjm-29	565	7	rajasingh	rajasingh	PROPN
bptjm-29	565	8	s	s	PROPN
bptjm-29	565	9	,	,	PUNCT
bptjm-29	565	10	et	et	PROPN
bptjm-29	565	11	al	al	PROPN
bptjm-29	565	12	.	.	PROPN
bptjm-29	565	13	role	role	NOUN
bptjm-29	565	14	of	of	ADP
bptjm-29	565	15	human	human	ADJ
bptjm-29	565	16	mesenchymal	mesenchymal	NOUN
bptjm-29	565	17	stem	stem	NOUN
bptjm-29	565	18	cells	cell	NOUN
bptjm-29	565	19	in	in	ADP
bptjm-29	565	20	regenerative	regenerative	ADJ
bptjm-29	565	21	therapy	therapy	NOUN
bptjm-29	565	22	.	.	PUNCT
bptjm-29	566	1	cells	cell	NOUN
bptjm-29	566	2	.	.	PUNCT
bptjm-29	567	1	2021;10(1):54	2021;10(1):54	X
bptjm-29	567	2	.	.	PUNCT
bptjm-29	567	3	doi:10.3390	doi:10.3390	PROPN
bptjm-29	567	4	/	/	SYM
bptjm-29	568	1	cells10010054	cells10010054	PROPN
bptjm-29	568	2	57	57	NUM
bptjm-29	568	3	.	.	PUNCT
bptjm-29	569	1	stem	stem	NOUN
bptjm-29	569	2	cells	cell	NOUN
bptjm-29	569	3	:	:	PUNCT
bptjm-29	569	4	past	past	ADJ
bptjm-29	569	5	,	,	PUNCT
bptjm-29	569	6	present	present	ADJ
bptjm-29	569	7	,	,	PUNCT
bptjm-29	569	8	and	and	CCONJ
bptjm-29	569	9	future	future	PROPN
bptjm-29	569	10	pmc	pmc	PROPN
bptjm-29	569	11	.	.	PROPN
bptjm-29	570	1	accessed	access	VERB
bptjm-29	570	2	july	july	PROPN
bptjm-29	570	3	24	24	NUM
bptjm-29	570	4	,	,	PUNCT
bptjm-29	570	5	2022	2022	NUM
bptjm-29	570	6	.	.	PUNCT
bptjm-29	571	1	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6390	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6390	PROPN
bptjm-29	572	1	367/	367/	NUM
bptjm-29	572	2	58	58	NUM
bptjm-29	572	3	.	.	PUNCT
bptjm-29	573	1	hernández	hernández	PROPN
bptjm-29	573	2	r	r	PROPN
bptjm-29	573	3	,	,	PUNCT
bptjm-29	573	4	jiménez	jiménez	PROPN
bptjm-29	573	5	-	-	PUNCT
bptjm-29	573	6	luna	luna	PROPN
bptjm-29	573	7	c	c	PROPN
bptjm-29	573	8	,	,	PUNCT
bptjm-29	573	9	perales	perales	PROPN
bptjm-29	573	10	-	-	PUNCT
bptjm-29	573	11	adán	adán	PROPN
bptjm-29	573	12	j	j	PROPN
bptjm-29	573	13	,	,	PUNCT
bptjm-29	573	14	perazzoli	perazzoli	VERB
bptjm-29	573	15	g	g	PROPN
bptjm-29	573	16	,	,	PUNCT
bptjm-29	573	17	melguizo	melguizo	PROPN
bptjm-29	573	18	c	c	X
bptjm-29	573	19	,	,	PUNCT
bptjm-29	573	20	prados	prados	PROPN
bptjm-29	573	21	j.	j.	PROPN
bptjm-29	573	22	di	di	PROPN
bptjm-29	573	23	�	�	PROPN
bptjm-29	573	24	erentiation	erentiation	NOUN
bptjm-29	573	25	of	of	ADP
bptjm-29	573	26	human	human	ADJ
bptjm-29	573	27	mesenchymal	mesenchymal	NOUN
bptjm-29	573	28	stem	stem	NOUN
bptjm-29	573	29	cells	cell	NOUN
bptjm-29	573	30	towards	towards	ADP
bptjm-29	573	31	neuronal	neuronal	ADJ
bptjm-29	573	32	lineage	lineage	NOUN
bptjm-29	573	33	:	:	PUNCT
bptjm-29	573	34	clinical	clinical	ADJ
bptjm-29	573	35	trials	trial	NOUN
bptjm-29	573	36	in	in	ADP
bptjm-29	573	37	nervous	nervous	ADJ
bptjm-29	573	38	system	system	NOUN
bptjm-29	573	39	disorders	disorder	NOUN
bptjm-29	573	40	.	.	PUNCT
bptjm-29	574	1	biomol	biomol	VERB
bptjm-29	574	2	ther	ther	ADV
bptjm-29	574	3	.	.	PUNCT
bptjm-29	575	1	2020;28(1):34	2020;28(1):34	NUM
bptjm-29	575	2	-	-	SYM
bptjm-29	575	3	44	44	NUM
bptjm-29	575	4	.	.	PUNCT
bptjm-29	576	1	doi:10.4062	doi:10.4062	PROPN
bptjm-29	576	2	/	/	SYM
bptjm-29	576	3	biomolther.2019.065	biomolther.2019.065	PROPN
bptjm-29	576	4	59	59	NUM
bptjm-29	576	5	.	.	PUNCT
bptjm-29	577	1	toh	toh	PROPN
bptjm-29	577	2	ws	ws	PROPN
bptjm-29	577	3	,	,	PUNCT
bptjm-29	577	4	lai	lai	PROPN
bptjm-29	577	5	rc	rc	PROPN
bptjm-29	577	6	,	,	PUNCT
bptjm-29	577	7	zhang	zhang	PROPN
bptjm-29	577	8	b	b	PROPN
bptjm-29	577	9	,	,	PUNCT
bptjm-29	577	10	lim	lim	PROPN
bptjm-29	577	11	sk	sk	PROPN
bptjm-29	577	12	.	.	PROPN
bptjm-29	577	13	msc	msc	PROPN
bptjm-29	577	14	exosome	exosome	PROPN
bptjm-29	577	15	works	work	VERB
bptjm-29	577	16	through	through	ADP
bptjm-29	577	17	a	a	DET
bptjm-29	577	18	protein	protein	NOUN
bptjm-29	577	19	-	-	PUNCT
bptjm-29	577	20	based	base	VERB
bptjm-29	577	21	mechanism	mechanism	NOUN
bptjm-29	577	22	of	of	ADP
bptjm-29	577	23	action	action	NOUN
bptjm-29	577	24	.	.	PUNCT
bptjm-29	578	1	biochem	biochem	PROPN
bptjm-29	578	2	soc	soc	PROPN
bptjm-29	578	3	trans	trans	PROPN
bptjm-29	578	4	.	.	PUNCT
bptjm-29	579	1	2018;46(4):843	2018;46(4):843	NUM
bptjm-29	579	2	-	-	PUNCT
bptjm-29	579	3	853	853	NUM
bptjm-29	579	4	.	.	PUNCT
bptjm-29	580	1	doi:10.1042	doi:10.1042	PROPN
bptjm-29	580	2	/	/	SYM
bptjm-29	580	3	bst20180079	bst20180079	PROPN
bptjm-29	580	4	60	60	NUM
bptjm-29	580	5	.	.	PUNCT
bptjm-29	581	1	ghannam	ghannam	PROPN
bptjm-29	581	2	s	s	PROPN
bptjm-29	581	3	,	,	PUNCT
bptjm-29	581	4	bou	bou	PROPN
bptjm-29	581	5	�	�	PROPN
bptjm-29	581	6	c	c	PROPN
bptjm-29	581	7	,	,	PUNCT
bptjm-29	581	8	djouad	djouad	PROPN
bptjm-29	581	9	f	f	PROPN
bptjm-29	581	10	,	,	PUNCT
bptjm-29	581	11	jorgensen	jorgensen	PROPN
bptjm-29	581	12	c	c	PROPN
bptjm-29	581	13	,	,	PUNCT
bptjm-29	581	14	noël	noël	PROPN
bptjm-29	581	15	d.	d.	PROPN
bptjm-29	581	16	immunosuppression	immunosuppression	NOUN
bptjm-29	581	17	by	by	ADP
bptjm-29	581	18	mesenchymal	mesenchymal	ADJ
bptjm-29	581	19	stem	stem	NOUN
bptjm-29	581	20	cells	cell	NOUN
bptjm-29	581	21	:	:	PUNCT
bptjm-29	581	22	mechanisms	mechanism	NOUN
bptjm-29	581	23	and	and	CCONJ
bptjm-29	581	24	clinical	clinical	ADJ
bptjm-29	581	25	applications	application	NOUN
bptjm-29	581	26	.	.	PUNCT
bptjm-29	582	1	stem	stem	NOUN
bptjm-29	582	2	cell	cell	NOUN
bptjm-29	582	3	res	re	NOUN
bptjm-29	582	4	ther	ther	ADV
bptjm-29	582	5	.	.	PUNCT
bptjm-29	583	1	2010;1(1):2	2010;1(1):2	NOUN
bptjm-29	583	2	.	.	PUNCT
bptjm-29	584	1	doi:10.1186	doi:10.1186	PROPN
bptjm-29	584	2	/	/	SYM
bptjm-29	584	3	scrt2	scrt2	PROPN
bptjm-29	584	4	61	61	NUM
bptjm-29	584	5	.	.	PUNCT
bptjm-29	585	1	frontiers	frontier	NOUN
bptjm-29	585	2	|	|	ADV
bptjm-29	585	3	mesenchymal	mesenchymal	NOUN
bptjm-29	585	4	stem	stem	NOUN
bptjm-29	585	5	cell	cell	NOUN
bptjm-29	585	6	-	-	PUNCT
bptjm-29	585	7	derived	derive	VERB
bptjm-29	585	8	extracellular	extracellular	ADJ
bptjm-29	585	9	vesicles	vesicle	NOUN
bptjm-29	585	10	:	:	PUNCT
bptjm-29	585	11	challenges	challenge	NOUN
bptjm-29	585	12	in	in	ADP
bptjm-29	585	13	clinical	clinical	ADJ
bptjm-29	585	14	applications	application	NOUN
bptjm-29	585	15	.	.	PUNCT
bptjm-29	586	1	accessed	access	VERB
bptjm-29	586	2	july	july	PROPN
bptjm-29	586	3	24	24	NUM
bptjm-29	586	4	,	,	PUNCT
bptjm-29	586	5	2022	2022	NUM
bptjm-29	586	6	.	.	PUNCT
bptjm-29	587	1	https://www.frontiersin.org/articles/10.3389/fcell.2020	https://www.frontiersin.org/articles/10.3389/fcell.2020	PROPN
bptjm-29	587	2	.	.	PUNCT
bptjm-29	588	1	00149	00149	NUM
bptjm-29	588	2	/	/	SYM
bptjm-29	588	3	full	full	ADJ
bptjm-29	588	4	62	62	NUM
bptjm-29	588	5	.	.	PUNCT
bptjm-29	589	1	what	what	PRON
bptjm-29	589	2	are	be	AUX
bptjm-29	589	3	stem	stem	NOUN
bptjm-29	589	4	cells	cell	NOUN
bptjm-29	589	5	?	?	PUNCT
bptjm-29	590	1	|	|	ADV
bptjm-29	590	2	where	where	SCONJ
bptjm-29	590	3	do	do	AUX
bptjm-29	590	4	stem	stem	NOUN
bptjm-29	590	5	cells	cell	NOUN
bptjm-29	590	6	come	come	VERB
bptjm-29	590	7	from	from	ADP
bptjm-29	590	8	?	?	PUNCT
bptjm-29	591	1	accessed	access	VERB
bptjm-29	591	2	july	july	PROPN
bptjm-29	591	3	24	24	NUM
bptjm-29	591	4	,	,	PUNCT
bptjm-29	591	5	2022	2022	NUM
bptjm-29	591	6	.	.	PUNCT
bptjm-29	591	7	https://www.cancer.org/treatment/treatments-and-sidee�ects/treatment-types/stem-cell-transplant/why-stem-c	https://www.cancer.org/treatment/treatments-and-sidee�ects/treatment-types/stem-cell-transplant/why-stem-c	PROPN
bptjm-29	591	8	ell-transplants-are-used.html	ell-transplants-are-used.html	PROPN
bptjm-29	591	9	63	63	NUM
bptjm-29	591	10	.	.	PUNCT
bptjm-29	592	1	bhartiya	bhartiya	PROPN
bptjm-29	592	2	d.	d.	PROPN
bptjm-29	592	3	are	be	AUX
bptjm-29	592	4	mesenchymal	mesenchymal	ADJ
bptjm-29	592	5	cells	cell	NOUN
bptjm-29	592	6	indeed	indeed	ADV
bptjm-29	592	7	pluripotent	pluripotent	VERB
bptjm-29	592	8	stem	stem	NOUN
bptjm-29	592	9	cells	cell	NOUN
bptjm-29	592	10	or	or	CCONJ
bptjm-29	592	11	just	just	ADV
bptjm-29	592	12	stromal	stromal	ADJ
bptjm-29	592	13	cells	cell	NOUN
bptjm-29	592	14	?	?	PUNCT
bptjm-29	592	15	oct-4	oct-4	PUNCT
bptjm-29	592	16	and	and	CCONJ
bptjm-29	592	17	vsels	vsel	NOUN
bptjm-29	592	18	biology	biology	NOUN
bptjm-29	592	19	has	have	AUX
bptjm-29	592	20	led	lead	VERB
bptjm-29	592	21	to	to	ADP
bptjm-29	592	22	better	well	ADJ
bptjm-29	592	23	understanding	understanding	NOUN
bptjm-29	592	24	.	.	PUNCT
bptjm-29	593	1	hindawi	hindawi	ADJ
bptjm-29	593	2	.	.	PUNCT
bptjm-29	594	1	2013	2013	NUM
bptjm-29	594	2	.	.	PUNCT
bptjm-29	595	1	https://doi.org/10.1155/2013/547501	https://doi.org/10.1155/2013/547501	PROPN
bptjm-29	595	2	berkeley	berkeley	PROPN
bptjm-29	595	3	pharma	pharma	PROPN
bptjm-29	595	4	tech	tech	NOUN
bptjm-29	595	5	journal	journal	NOUN
bptjm-29	595	6	of	of	ADP
bptjm-29	595	7	medicine	medicine	NOUN
bptjm-29	595	8	|	|	ADV
bptjm-29	595	9	102	102	NUM
bptjm-29	595	10	64	64	NUM
bptjm-29	595	11	.	.	PUNCT
bptjm-29	596	1	shen	shen	PROPN
bptjm-29	596	2	cn	cn	PROPN
bptjm-29	596	3	,	,	PUNCT
bptjm-29	596	4	burke	burke	PROPN
bptjm-29	596	5	zd	zd	PROPN
bptjm-29	596	6	,	,	PUNCT
bptjm-29	596	7	tosh	tosh	PROPN
bptjm-29	596	8	d.	d.	PROPN
bptjm-29	596	9	transdi	transdi	PROPN
bptjm-29	596	10	�	�	PROPN
bptjm-29	596	11	erentiation	erentiation	PROPN
bptjm-29	596	12	,	,	PUNCT
bptjm-29	596	13	metaplasia	metaplasia	NOUN
bptjm-29	596	14	and	and	CCONJ
bptjm-29	596	15	tissue	tissue	NOUN
bptjm-29	596	16	regeneration	regeneration	NOUN
bptjm-29	596	17	.	.	PUNCT
bptjm-29	597	1	organogenesis	organogenesis	NOUN
bptjm-29	597	2	.	.	PUNCT
bptjm-29	598	1	2004;1(2):36	2004;1(2):36	NUM
bptjm-29	598	2	-	-	SYM
bptjm-29	598	3	44	44	NUM
bptjm-29	598	4	.	.	PUNCT
bptjm-29	598	5	doi:10.4161	doi:10.4161	PROPN
bptjm-29	598	6	/	/	SYM
bptjm-29	598	7	org.1.2.1409	org.1.2.1409	PROPN
bptjm-29	598	8	65	65	NUM
bptjm-29	598	9	.	.	PUNCT
bptjm-29	599	1	an	an	DET
bptjm-29	599	2	interdisciplinary	interdisciplinary	ADJ
bptjm-29	599	3	approach	approach	NOUN
bptjm-29	599	4	and	and	CCONJ
bptjm-29	599	5	characterization	characterization	NOUN
bptjm-29	599	6	of	of	ADP
bptjm-29	599	7	neuronal	neuronal	ADJ
bptjm-29	599	8	cells	cell	NOUN
bptjm-29	599	9	transdi	transdi	NOUN
bptjm-29	599	10	�	�	PROPN
bptjm-29	599	11	erentiated	erentiate	VERB
bptjm-29	599	12	from	from	ADP
bptjm-29	599	13	human	human	ADJ
bptjm-29	599	14	mesenchymal	mesenchymal	NOUN
bptjm-29	599	15	stem	stem	NOUN
bptjm-29	599	16	cells	cell	NOUN
bptjm-29	599	17	|	|	ADV
bptjm-29	599	18	stem	stem	VERB
bptjm-29	599	19	cells	cell	NOUN
bptjm-29	599	20	and	and	CCONJ
bptjm-29	599	21	development	development	NOUN
bptjm-29	599	22	.	.	PUNCT
bptjm-29	600	1	accessed	access	VERB
bptjm-29	600	2	july	july	PROPN
bptjm-29	600	3	24	24	NUM
bptjm-29	600	4	,	,	PUNCT
bptjm-29	600	5	2022	2022	NUM
bptjm-29	600	6	.	.	PUNCT
bptjm-29	601	1	https://www.liebertpub.com/doi/abs/10.1089/scd.2007	https://www.liebertpub.com/doi/abs/10.1089/scd.2007	VERB
bptjm-29	601	2	.0011	.0011	PROPN
bptjm-29	601	3	66	66	NUM
bptjm-29	601	4	.	.	PUNCT
bptjm-29	602	1	mesenchymal	mesenchymal	ADJ
bptjm-29	602	2	stem	stem	NOUN
bptjm-29	602	3	cells	cell	NOUN
bptjm-29	602	4	:	:	PUNCT
bptjm-29	602	5	immunomodulatory	immunomodulatory	ADJ
bptjm-29	602	6	capability	capability	NOUN
bptjm-29	602	7	and	and	CCONJ
bptjm-29	602	8	clinical	clinical	ADJ
bptjm-29	602	9	potential	potential	NOUN
bptjm-29	602	10	in	in	ADP
bptjm-29	602	11	immune	immune	ADJ
bptjm-29	602	12	diseases	disease	NOUN
bptjm-29	602	13	.	.	PUNCT
bptjm-29	603	1	sciencedirect	sciencedirect	PROPN
bptjm-29	603	2	.	.	PROPN
bptjm-29	604	1	accessed	access	VERB
bptjm-29	604	2	july	july	PROPN
bptjm-29	604	3	24	24	NUM
bptjm-29	604	4	,	,	PUNCT
bptjm-29	604	5	2022	2022	NUM
bptjm-29	604	6	.	.	PUNCT
bptjm-29	605	1	https://www.sciencedirect.com/science/article/pii/s235	https://www.sciencedirect.com/science/article/pii/s235	ADJ
bptjm-29	605	2	2177515000047	2177515000047	NUM
bptjm-29	605	3	67	67	NUM
bptjm-29	605	4	.	.	PUNCT
bptjm-29	606	1	a	a	DET
bptjm-29	606	2	guide	guide	NOUN
bptjm-29	606	3	to	to	ADP
bptjm-29	606	4	chemokines	chemokine	NOUN
bptjm-29	606	5	and	and	CCONJ
bptjm-29	606	6	their	their	PRON
bptjm-29	606	7	receptors	receptor	NOUN
bptjm-29	606	8	pmc	pmc	PROPN
bptjm-29	606	9	.	.	PUNCT
bptjm-29	606	10	accessed	access	VERB
bptjm-29	606	11	july	july	PROPN
bptjm-29	606	12	24	24	NUM
bptjm-29	606	13	,	,	PUNCT
bptjm-29	606	14	2022	2022	NUM
bptjm-29	606	15	.	.	PUNCT
bptjm-29	607	1	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6120	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6120	PROPN
bptjm-29	607	2	486/	486/	NUM
bptjm-29	607	3	68	68	NUM
bptjm-29	607	4	.	.	PUNCT
bptjm-29	608	1	comparative	comparative	ADJ
bptjm-29	608	2	study	study	NOUN
bptjm-29	608	3	of	of	ADP
bptjm-29	608	4	the	the	DET
bptjm-29	608	5	neural	neural	PROPN
bptjm-29	608	6	di	di	PROPN
bptjm-29	608	7	�	�	PROPN
bptjm-29	608	8	erentiation	erentiation	NOUN
bptjm-29	608	9	capacity	capacity	NOUN
bptjm-29	608	10	of	of	ADP
bptjm-29	608	11	mesenchymal	mesenchymal	ADJ
bptjm-29	608	12	stromal	stromal	ADJ
bptjm-29	608	13	cells	cell	NOUN
bptjm-29	608	14	from	from	ADP
bptjm-29	608	15	di	di	NOUN
bptjm-29	608	16	�	�	PROPN
bptjm-29	608	17	erent	erent	NOUN
bptjm-29	608	18	tissue	tissue	NOUN
bptjm-29	608	19	sources	source	NOUN
bptjm-29	608	20	:	:	PUNCT
bptjm-29	608	21	an	an	DET
bptjm-29	608	22	approach	approach	NOUN
bptjm-29	608	23	for	for	ADP
bptjm-29	608	24	their	their	PRON
bptjm-29	608	25	use	use	NOUN
bptjm-29	608	26	in	in	ADP
bptjm-29	608	27	neural	neural	ADJ
bptjm-29	608	28	regeneration	regeneration	NOUN
bptjm-29	608	29	therapies	therapy	NOUN
bptjm-29	608	30	|	|	ADV
bptjm-29	608	31	plos	plo	VERB
bptjm-29	608	32	one	one	NUM
bptjm-29	608	33	.	.	PUNCT
bptjm-29	609	1	accessed	access	VERB
bptjm-29	609	2	july	july	PROPN
bptjm-29	609	3	24	24	NUM
bptjm-29	609	4	,	,	PUNCT
bptjm-29	609	5	2022	2022	NUM
bptjm-29	609	6	.	.	PUNCT
bptjm-29	610	1	https://journals.plos.org/plosone/article?id=10.1371/jo	https://journals.plos.org/plosone/article?id=10.1371/jo	NOUN
bptjm-29	610	2	urnal.pone.0213032	urnal.pone.0213032	PROPN
bptjm-29	610	3	69	69	NUM
bptjm-29	610	4	.	.	PUNCT
bptjm-29	611	1	mancuso	mancuso	PROPN
bptjm-29	611	2	p	p	PROPN
bptjm-29	611	3	,	,	PUNCT
bptjm-29	611	4	raman	raman	NOUN
bptjm-29	611	5	s	s	PROPN
bptjm-29	611	6	,	,	PUNCT
bptjm-29	611	7	glynn	glynn	PROPN
bptjm-29	611	8	a	a	X
bptjm-29	611	9	,	,	PUNCT
bptjm-29	611	10	barry	barry	PROPN
bptjm-29	611	11	f	f	PROPN
bptjm-29	611	12	,	,	PUNCT
bptjm-29	611	13	murphy	murphy	PROPN
bptjm-29	611	14	jm	jm	PROPN
bptjm-29	611	15	.	.	PROPN
bptjm-29	611	16	mesenchymal	mesenchymal	ADJ
bptjm-29	611	17	stem	stem	NOUN
bptjm-29	611	18	cell	cell	NOUN
bptjm-29	611	19	therapy	therapy	NOUN
bptjm-29	611	20	for	for	ADP
bptjm-29	611	21	osteoarthritis	osteoarthritis	NOUN
bptjm-29	611	22	:	:	PUNCT
bptjm-29	611	23	the	the	DET
bptjm-29	611	24	critical	critical	ADJ
bptjm-29	611	25	role	role	NOUN
bptjm-29	611	26	of	of	ADP
bptjm-29	611	27	the	the	DET
bptjm-29	611	28	cell	cell	NOUN
bptjm-29	611	29	secretome	secretome	NOUN
bptjm-29	611	30	.	.	PUNCT
bptjm-29	612	1	front	front	ADJ
bptjm-29	612	2	bioeng	bioeng	PROPN
bptjm-29	612	3	biotechnol	biotechnol	NOUN
bptjm-29	612	4	.	.	PUNCT
bptjm-29	613	1	2019;7	2019;7	NOUN
bptjm-29	613	2	.	.	PUNCT
bptjm-29	613	3	accessed	access	VERB
bptjm-29	613	4	july	july	PROPN
bptjm-29	613	5	24	24	NUM
bptjm-29	613	6	,	,	PUNCT
bptjm-29	613	7	2022	2022	NUM
bptjm-29	613	8	.	.	PUNCT
bptjm-29	614	1	https://www.frontiersin.org/articles/10.3389/fbioe.201	https://www.frontiersin.org/articles/10.3389/fbioe.201	VERB
bptjm-29	614	2	9.00009	9.00009	NUM
bptjm-29	614	3	70	70	NUM
bptjm-29	614	4	.	.	PUNCT
bptjm-29	615	1	paliwal	paliwal	PROPN
bptjm-29	615	2	s	s	PROPN
bptjm-29	615	3	,	,	PUNCT
bptjm-29	615	4	chaudhuri	chaudhuri	PROPN
bptjm-29	615	5	r	r	PROPN
bptjm-29	615	6	,	,	PUNCT
bptjm-29	615	7	agrawal	agrawal	PROPN
bptjm-29	615	8	a	a	PRON
bptjm-29	615	9	,	,	PUNCT
bptjm-29	615	10	mohanty	mohanty	PROPN
bptjm-29	615	11	s.	s.	PROPN
bptjm-29	615	12	regenerative	regenerative	ADJ
bptjm-29	615	13	abilities	ability	NOUN
bptjm-29	615	14	of	of	ADP
bptjm-29	615	15	mesenchymal	mesenchymal	ADJ
bptjm-29	615	16	stem	stem	NOUN
bptjm-29	615	17	cells	cell	NOUN
bptjm-29	615	18	through	through	ADP
bptjm-29	615	19	mitochondrial	mitochondrial	ADJ
bptjm-29	615	20	transfer	transfer	NOUN
bptjm-29	615	21	.	.	PUNCT
bptjm-29	616	1	j	j	PROPN
bptjm-29	616	2	biomed	biome	VERB
bptjm-29	616	3	sci	sci	PROPN
bptjm-29	616	4	.	.	PUNCT
bptjm-29	617	1	2018;25(1):31	2018;25(1):31	NUM
bptjm-29	617	2	.	.	PUNCT
bptjm-29	617	3	doi:10.1186	doi:10.1186	PROPN
bptjm-29	617	4	/	/	SYM
bptjm-29	617	5	s12929	s12929	PROPN
bptjm-29	617	6	-	-	PUNCT
bptjm-29	617	7	018	018	NUM
bptjm-29	617	8	-	-	PUNCT
bptjm-29	617	9	0429	0429	NUM
bptjm-29	617	10	-	-	SYM
bptjm-29	617	11	1	1	NUM
bptjm-29	617	12	71	71	NUM
bptjm-29	617	13	.	.	PUNCT
bptjm-29	618	1	petrou	petrou	PROPN
bptjm-29	618	2	p	p	PROPN
bptjm-29	618	3	,	,	PUNCT
bptjm-29	618	4	gothelf	gothelf	NOUN
bptjm-29	618	5	y	y	NOUN
bptjm-29	618	6	,	,	PUNCT
bptjm-29	618	7	argov	argov	ADJ
bptjm-29	618	8	z	z	PROPN
bptjm-29	618	9	,	,	PUNCT
bptjm-29	618	10	et	et	PROPN
bptjm-29	618	11	al	al	PROPN
bptjm-29	618	12	.	.	PROPN
bptjm-29	618	13	safety	safety	NOUN
bptjm-29	618	14	and	and	CCONJ
bptjm-29	618	15	clinical	clinical	ADJ
bptjm-29	618	16	e	e	NOUN
bptjm-29	618	17	�	�	NOUN
bptjm-29	618	18	ects	ect	NOUN
bptjm-29	618	19	of	of	ADP
bptjm-29	618	20	mesenchymal	mesenchymal	NOUN
bptjm-29	618	21	stem	stem	NOUN
bptjm-29	618	22	cells	cell	NOUN
bptjm-29	618	23	secreting	secrete	VERB
bptjm-29	618	24	neurotrophic	neurotrophic	ADJ
bptjm-29	618	25	factor	factor	NOUN
bptjm-29	618	26	transplantation	transplantation	NOUN
bptjm-29	618	27	in	in	ADP
bptjm-29	618	28	patients	patient	NOUN
bptjm-29	618	29	with	with	ADP
bptjm-29	618	30	amyotrophic	amyotrophic	ADJ
bptjm-29	618	31	lateral	lateral	ADJ
bptjm-29	618	32	sclerosis	sclerosis	NOUN
bptjm-29	618	33	:	:	PUNCT
bptjm-29	618	34	results	result	NOUN
bptjm-29	618	35	of	of	ADP
bptjm-29	618	36	phase	phase	NOUN
bptjm-29	618	37	1/2	1/2	NUM
bptjm-29	618	38	and	and	CCONJ
bptjm-29	618	39	2a	2a	NUM
bptjm-29	618	40	clinical	clinical	ADJ
bptjm-29	618	41	trials	trial	NOUN
bptjm-29	618	42	.	.	PUNCT
bptjm-29	619	1	jama	jama	PROPN
bptjm-29	619	2	neurol	neurol	PROPN
bptjm-29	619	3	.	.	PUNCT
bptjm-29	620	1	2016;73(3):337	2016;73(3):337	NUM
bptjm-29	620	2	.	.	PUNCT
bptjm-29	621	1	doi:10.1001	doi:10.1001	PROPN
bptjm-29	621	2	/	/	SYM
bptjm-29	621	3	jamaneurol.2015.4321	jamaneurol.2015.4321	PROPN
bptjm-29	621	4	72	72	NUM
bptjm-29	621	5	.	.	PUNCT
bptjm-29	622	1	clinical	clinical	ADJ
bptjm-29	622	2	applications	application	NOUN
bptjm-29	622	3	of	of	ADP
bptjm-29	622	4	mesenchymal	mesenchymal	ADJ
bptjm-29	622	5	stem	stem	NOUN
bptjm-29	622	6	cells	cell	NOUN
bptjm-29	622	7	|	|	ADV
bptjm-29	622	8	journal	journal	NOUN
bptjm-29	622	9	of	of	ADP
bptjm-29	622	10	hematology	hematology	PROPN
bptjm-29	622	11	&	&	CCONJ
bptjm-29	622	12	oncology	oncology	NOUN
bptjm-29	622	13	|	|	ADV
bptjm-29	622	14	full	full	ADJ
bptjm-29	622	15	text	text	NOUN
bptjm-29	622	16	.	.	PUNCT
bptjm-29	623	1	accessed	access	VERB
bptjm-29	623	2	july	july	PROPN
bptjm-29	623	3	24	24	NUM
bptjm-29	623	4	,	,	PUNCT
bptjm-29	623	5	2022	2022	NUM
bptjm-29	623	6	.	.	PUNCT
bptjm-29	624	1	https://jhoonline.biomedcentral.com/articles/10.1186/	https://jhoonline.biomedcentral.com/articles/10.1186/	PROPN
bptjm-29	624	2	1756	1756	NUM
bptjm-29	624	3	-	-	SYM
bptjm-29	624	4	8722	8722	NUM
bptjm-29	624	5	-	-	SYM
bptjm-29	624	6	5	5	NUM
bptjm-29	624	7	-	-	SYM
bptjm-29	624	8	19	19	NUM
bptjm-29	624	9	73	73	NUM
bptjm-29	624	10	.	.	PUNCT
bptjm-29	625	1	de	de	PROPN
bptjm-29	625	2	�	�	PROPN
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bptjm-29	625	4	of	of	ADP
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bptjm-29	625	6	nci	nci	PROPN
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bptjm-29	625	10	terms	term	NOUN
bptjm-29	625	11	nci	nci	PROPN
bptjm-29	625	12	.	.	PUNCT
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bptjm-29	626	2	february	february	PROPN
bptjm-29	626	3	2	2	NUM
bptjm-29	626	4	,	,	PUNCT
bptjm-29	626	5	2011	2011	NUM
bptjm-29	626	6	.	.	PUNCT
bptjm-29	627	1	accessed	access	VERB
bptjm-29	627	2	august	august	PROPN
bptjm-29	627	3	5	5	NUM
bptjm-29	627	4	,	,	PUNCT
bptjm-29	627	5	2022	2022	NUM
bptjm-29	627	6	.	.	PUNCT
bptjm-29	628	1	https://www.cancer.gov/publications/dictionaries/cance	https://www.cancer.gov/publications/dictionaries/cance	NOUN
bptjm-29	629	1	r	r	NOUN
bptjm-29	629	2	-	-	PUNCT
bptjm-29	629	3	terms	term	NOUN
bptjm-29	629	4	/	/	SYM
bptjm-29	629	5	def	def	ADJ
bptjm-29	629	6	/	/	SYM
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bptjm-29	629	8	74	74	NUM
bptjm-29	629	9	.	.	PUNCT
bptjm-29	630	1	faravelli	faravelli	PROPN
bptjm-29	631	1	i	i	PROPN
bptjm-29	631	2	,	,	PUNCT
bptjm-29	631	3	bucchia	bucchia	VERB
bptjm-29	631	4	m	m	PRON
bptjm-29	631	5	,	,	PUNCT
bptjm-29	631	6	rinchetti	rinchetti	VERB
bptjm-29	631	7	p	p	PROPN
bptjm-29	631	8	,	,	PUNCT
bptjm-29	631	9	et	et	PROPN
bptjm-29	631	10	al	al	PROPN
bptjm-29	631	11	.	.	PROPN
bptjm-29	631	12	motor	motor	PROPN
bptjm-29	631	13	neuron	neuron	PROPN
bptjm-29	631	14	derivation	derivation	NOUN
bptjm-29	631	15	from	from	ADP
bptjm-29	631	16	human	human	ADJ
bptjm-29	631	17	embryonic	embryonic	NOUN
bptjm-29	631	18	and	and	CCONJ
bptjm-29	631	19	induced	induce	VERB
bptjm-29	631	20	pluripotent	pluripotent	ADJ
bptjm-29	631	21	stem	stem	NOUN
bptjm-29	631	22	cells	cell	NOUN
bptjm-29	631	23	:	:	PUNCT
bptjm-29	631	24	experimental	experimental	ADJ
bptjm-29	631	25	approaches	approach	NOUN
bptjm-29	631	26	and	and	CCONJ
bptjm-29	631	27	clinical	clinical	ADJ
bptjm-29	631	28	perspectives	perspective	NOUN
bptjm-29	631	29	.	.	PUNCT
bptjm-29	632	1	stem	stem	NOUN
bptjm-29	632	2	cell	cell	NOUN
bptjm-29	632	3	res	re	NOUN
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bptjm-29	632	5	.	.	PUNCT
bptjm-29	633	1	2014;5(4):87	2014;5(4):87	X
bptjm-29	633	2	.	.	PUNCT
bptjm-29	633	3	doi:10.1186	doi:10.1186	PROPN
bptjm-29	633	4	/	/	SYM
bptjm-29	633	5	scrt476	scrt476	PROPN
bptjm-29	633	6	75	75	NUM
bptjm-29	633	7	.	.	PUNCT
bptjm-29	633	8	mao	mao	PROPN
bptjm-29	634	1	z	z	PROPN
bptjm-29	634	2	,	,	PUNCT
bptjm-29	634	3	zhang	zhang	PROPN
bptjm-29	634	4	s	s	PROPN
bptjm-29	634	5	,	,	PUNCT
bptjm-29	634	6	chen	chen	PROPN
bptjm-29	634	7	h.	h.	PROPN
bptjm-29	634	8	stem	stem	NOUN
bptjm-29	634	9	cell	cell	NOUN
bptjm-29	634	10	therapy	therapy	NOUN
bptjm-29	634	11	for	for	ADP
bptjm-29	634	12	amyotrophic	amyotrophic	ADJ
bptjm-29	634	13	lateral	lateral	ADJ
bptjm-29	634	14	sclerosis	sclerosis	NOUN
bptjm-29	634	15	.	.	PUNCT
bptjm-29	635	1	cell	cell	NOUN
bptjm-29	635	2	regen	regen	PROPN
bptjm-29	635	3	.	.	PUNCT
bptjm-29	636	1	2015;4(1):4:11	2015;4(1):4:11	NUM
bptjm-29	636	2	.	.	PUNCT
bptjm-29	636	3	doi:10.1186	doi:10.1186	PROPN
bptjm-29	636	4	/	/	SYM
bptjm-29	636	5	s13619	s13619	PROPN
bptjm-29	636	6	-	-	PUNCT
bptjm-29	636	7	015	015	NUM
bptjm-29	636	8	-	-	PUNCT
bptjm-29	636	9	0026	0026	NUM
bptjm-29	636	10	-	-	SYM
bptjm-29	636	11	7	7	NUM
bptjm-29	636	12	berkeley	berkeley	PROPN
bptjm-29	636	13	pharma	pharma	PROPN
bptjm-29	636	14	tech	tech	NOUN
bptjm-29	636	15	journal	journal	NOUN
bptjm-29	636	16	of	of	ADP
bptjm-29	636	17	medicine	medicine	NOUN
bptjm-29	636	18	|	|	ADV
bptjm-29	636	19	103	103	NUM
bptjm-29	636	20	front	front	ADJ
bptjm-29	636	21	page	page	NOUN
bptjm-29	636	22	yalamanchili	yalamanchili	NOUN
bptjm-29	636	23	et	et	PROPN
bptjm-29	636	24	al	al	PROPN
bptjm-29	636	25	.	.	PROPN
bptjm-29	636	26	body	body	PROPN
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bptjm-29	636	28	et	et	PROPN
bptjm-29	636	29	al	al	PROPN
bptjm-29	636	30	.	.	PROPN
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bptjm-29	637	2	et	et	PROPN
bptjm-29	637	3	al	al	PROPN
bptjm-29	637	4	.	.	PUNCT