id	sid	tid	token	lemma	pos
bptjm-41	1	1	the	the	DET
bptjm-41	1	2	role	role	NOUN
bptjm-41	1	3	of	of	ADP
bptjm-41	1	4	the	the	DET
bptjm-41	1	5	gut	gut	NOUN
bptjm-41	1	6	microbiome	microbiome	NOUN
bptjm-41	1	7	in	in	ADP
bptjm-41	1	8	neuromodulation	neuromodulation	NOUN
bptjm-41	1	9	therapies	therapy	NOUN
bptjm-41	1	10	as	as	ADP
bptjm-41	1	11	a	a	DET
bptjm-41	1	12	potential	potential	ADJ
bptjm-41	1	13	treatment	treatment	NOUN
bptjm-41	1	14	adjunct	adjunct	ADJ
bptjm-41	1	15	for	for	ADP
bptjm-41	1	16	multiple	multiple	ADJ
bptjm-41	1	17	sclerosis	sclerosis	NOUN
bptjm-41	1	18	abstract	abstract	PROPN
bptjm-41	1	19	berkeley	berkeley	PROPN
bptjm-41	1	20	pharma	pharma	PROPN
bptjm-41	1	21	tech	tech	NOUN
bptjm-41	1	22	journal	journal	NOUN
bptjm-41	1	23	of	of	ADP
bptjm-41	1	24	medicine	medicine	NOUN
bptjm-41	1	25	correspondence	correspondence	NOUN
bptjm-41	1	26	:	:	PUNCT
bptjm-41	1	27	jwlarrick@gmail.com	jwlarrick@gmail.com	X
bptjm-41	2	1	keywords	keyword	NOUN
bptjm-41	2	2	:	:	PUNCT
bptjm-41	2	3	chloroquine	chloroquine	NOUN
bptjm-41	2	4	,	,	PUNCT
bptjm-41	2	5	hydrochloroquine	hydrochloroquine	NOUN
bptjm-41	2	6	,	,	PUNCT
bptjm-41	2	7	autophagy	autophagy	ADJ
bptjm-41	2	8	,	,	PUNCT
bptjm-41	2	9	aging	aging	NOUN
bptjm-41	2	10	,	,	PUNCT
bptjm-41	2	11	geroprotection	geroprotection	NOUN
bptjm-41	2	12	submitted	submit	VERB
bptjm-41	2	13	:	:	PUNCT
bptjm-41	2	14	march	march	PROPN
bptjm-41	2	15	10	10	NUM
bptjm-41	2	16	,	,	PUNCT
bptjm-41	2	17	2023	2023	NUM
bptjm-41	2	18	accepted	accept	VERB
bptjm-41	2	19	:	:	PUNCT
bptjm-41	2	20	april	april	PROPN
bptjm-41	2	21	6	6	NUM
bptjm-41	2	22	,	,	PUNCT
bptjm-41	2	23	2023	2023	NUM
bptjm-41	2	24	published	publish	VERB
bptjm-41	2	25	:	:	PUNCT
bptjm-41	2	26	june	june	PROPN
bptjm-41	2	27	30	30	NUM
bptjm-41	2	28	,	,	PUNCT
bptjm-41	2	29	2023	2023	NUM
bptjm-41	2	30	full	full	ADJ
bptjm-41	2	31	open	open	ADJ
bptjm-41	2	32	access	access	NOUN
bptjm-41	2	33	creative	creative	ADJ
bptjm-41	2	34	commons	common	NOUN
bptjm-41	2	35	attribution	attribution	NOUN
bptjm-41	2	36	license	license	VERB
bptjm-41	2	37	4.0	4.0	NUM
bptjm-41	2	38	autophagy	autophagy	VERB
bptjm-41	2	39	,	,	PUNCT
bptjm-41	2	40	the	the	DET
bptjm-41	2	41	turnover	turnover	NOUN
bptjm-41	2	42	of	of	ADP
bptjm-41	2	43	cellular	cellular	ADJ
bptjm-41	2	44	components	component	NOUN
bptjm-41	2	45	including	include	VERB
bptjm-41	2	46	organelles	organelle	NOUN
bptjm-41	2	47	,	,	PUNCT
bptjm-41	2	48	declines	decline	VERB
bptjm-41	2	49	with	with	ADP
bptjm-41	2	50	age	age	NOUN
bptjm-41	2	51	.	.	PUNCT
bptjm-41	3	1	thus	thus	ADV
bptjm-41	3	2	,	,	PUNCT
bptjm-41	3	3	enhancement	enhancement	NOUN
bptjm-41	3	4	of	of	ADP
bptjm-41	3	5	this	this	DET
bptjm-41	3	6	characteristic	characteristic	ADJ
bptjm-41	3	7	process	process	NOUN
bptjm-41	3	8	is	be	AUX
bptjm-41	3	9	hypothesized	hypothesize	VERB
bptjm-41	3	10	to	to	PART
bptjm-41	3	11	improve	improve	VERB
bptjm-41	3	12	health	health	NOUN
bptjm-41	3	13	and	and	CCONJ
bptjm-41	3	14	extend	extend	VERB
bptjm-41	3	15	lifespan	lifespan	NOUN
bptjm-41	3	16	.	.	PUNCT
bptjm-41	4	1	two	two	NUM
bptjm-41	4	2	recent	recent	ADJ
bptjm-41	4	3	papers	paper	NOUN
bptjm-41	4	4	present	present	VERB
bptjm-41	4	5	data	datum	NOUN
bptjm-41	4	6	indicating	indicate	VERB
bptjm-41	4	7	that	that	SCONJ
bptjm-41	4	8	contrary	contrary	ADJ
bptjm-41	4	9	to	to	ADP
bptjm-41	4	10	expectation	expectation	NOUN
bptjm-41	4	11	,	,	PUNCT
bptjm-41	4	12	chloroquine	chloroquine	NOUN
bptjm-41	4	13	(	(	PUNCT
bptjm-41	4	14	cq	cq	NOUN
bptjm-41	4	15	)	)	PUNCT
bptjm-41	4	16	,	,	PUNCT
bptjm-41	4	17	a	a	DET
bptjm-41	4	18	nominal	nominal	ADJ
bptjm-41	4	19	inhibitor	inhibitor	NOUN
bptjm-41	4	20	of	of	ADP
bptjm-41	4	21	autophagy	autophagy	NOUN
bptjm-41	4	22	,	,	PUNCT
bptjm-41	4	23	extended	extend	VERB
bptjm-41	4	24	the	the	DET
bptjm-41	4	25	lifespan	lifespan	NOUN
bptjm-41	4	26	of	of	ADP
bptjm-41	4	27	middle	middle	ADJ
bptjm-41	4	28	-	-	PUNCT
bptjm-41	4	29	aged	aged	ADJ
bptjm-41	4	30	mice	mouse	NOUN
bptjm-41	4	31	and	and	CCONJ
bptjm-41	4	32	rats	rat	NOUN
bptjm-41	4	33	by	by	ADP
bptjm-41	4	34	~10	~10	NOUN
bptjm-41	4	35	%	%	NOUN
bptjm-41	4	36	.	.	PUNCT
bptjm-41	5	1	details	detail	NOUN
bptjm-41	5	2	of	of	ADP
bptjm-41	5	3	these	these	DET
bptjm-41	5	4	studies	study	NOUN
bptjm-41	5	5	provide	provide	VERB
bptjm-41	5	6	a	a	DET
bptjm-41	5	7	cautionary	cautionary	ADJ
bptjm-41	5	8	tale	tale	NOUN
bptjm-41	5	9	regarding	regard	VERB
bptjm-41	5	10	traditional	traditional	ADJ
bptjm-41	5	11	reagents	reagent	NOUN
bptjm-41	5	12	or	or	CCONJ
bptjm-41	5	13	“	"	PUNCT
bptjm-41	5	14	tool	tool	NOUN
bptjm-41	5	15	compounds	compound	NOUN
bptjm-41	5	16	”	"	PUNCT
bptjm-41	5	17	of	of	ADP
bptjm-41	5	18	“	"	PUNCT
bptjm-41	5	19	established	establish	VERB
bptjm-41	5	20	”	"	PUNCT
bptjm-41	5	21	mechanisms	mechanism	NOUN
bptjm-41	5	22	often	often	ADV
bptjm-41	5	23	used	use	VERB
bptjm-41	5	24	in	in	ADP
bptjm-41	5	25	cellular	cellular	ADJ
bptjm-41	5	26	biological	biological	ADJ
bptjm-41	5	27	research	research	NOUN
bptjm-41	5	28	.	.	PUNCT
bptjm-41	6	1	however	however	ADV
bptjm-41	6	2	,	,	PUNCT
bptjm-41	6	3	these	these	DET
bptjm-41	6	4	and	and	CCONJ
bptjm-41	6	5	earlier	early	ADJ
bptjm-41	6	6	studies	study	NOUN
bptjm-41	6	7	support	support	VERB
bptjm-41	6	8	a	a	DET
bptjm-41	6	9	deeper	deep	ADJ
bptjm-41	6	10	investigation	investigation	NOUN
bptjm-41	6	11	of	of	ADP
bptjm-41	6	12	cq	cq	NOUN
bptjm-41	6	13	or	or	CCONJ
bptjm-41	6	14	its	its	PRON
bptjm-41	6	15	more	more	ADV
bptjm-41	6	16	commonly	commonly	ADV
bptjm-41	6	17	used	use	VERB
bptjm-41	6	18	clinical	clinical	ADJ
bptjm-41	6	19	analog	analog	NOUN
bptjm-41	6	20	,	,	PUNCT
bptjm-41	6	21	hydroxychloroquine	hydroxychloroquine	NOUN
bptjm-41	6	22	(	(	PUNCT
bptjm-41	6	23	hcq	hcq	PROPN
bptjm-41	6	24	)	)	PUNCT
bptjm-41	6	25	,	,	PUNCT
bptjm-41	6	26	as	as	ADP
bptjm-41	6	27	potential	potential	ADJ
bptjm-41	6	28	drugs	drug	NOUN
bptjm-41	6	29	to	to	PART
bptjm-41	6	30	increase	increase	VERB
bptjm-41	6	31	health	health	NOUN
bptjm-41	6	32	span	span	NOUN
bptjm-41	6	33	and	and	CCONJ
bptjm-41	6	34	slow	slow	VERB
bptjm-41	6	35	the	the	DET
bptjm-41	6	36	aging	age	VERB
bptjm-41	6	37	process	process	NOUN
bptjm-41	6	38	.	.	PUNCT
bptjm-41	7	1	chloroquine	chloroquine	NOUN
bptjm-41	7	2	defeats	defeat	NOUN
bptjm-41	7	3	aging	age	VERB
bptjm-41	7	4	?	?	PUNCT
bptjm-41	8	1	by	by	ADP
bptjm-41	8	2	:	:	PUNCT
bptjm-41	8	3	james	james	PROPN
bptjm-41	8	4	w.	w.	PROPN
bptjm-41	8	5	larrick	larrick	PROPN
bptjm-41	8	6	,	,	PUNCT
bptjm-41	8	7	m.d	m.d	PROPN
bptjm-41	8	8	.	.	PROPN
bptjm-41	8	9	ph.d	ph.d	PROPN
bptjm-41	8	10	.	.	PROPN
bptjm-41	8	11	and	and	CCONJ
bptjm-41	8	12	jasmine	jasmine	PROPN
bptjm-41	8	13	w.	w.	PROPN
bptjm-41	8	14	larrick	larrick	PROPN
bptjm-41	8	15	introduction	introduction	NOUN
bptjm-41	8	16	1.1	1.1	NUM
bptjm-41	8	17	autophagy	autophagy	NOUN
bptjm-41	8	18	autophagy	autophagy	VERB
bptjm-41	8	19	,	,	PUNCT
bptjm-41	8	20	literally	literally	ADV
bptjm-41	8	21	“	"	PUNCT
bptjm-41	8	22	self	self	NOUN
bptjm-41	8	23	-	-	PUNCT
bptjm-41	8	24	eating	eating	NOUN
bptjm-41	8	25	,	,	PUNCT
bptjm-41	8	26	"	"	PUNCT
bptjm-41	8	27	was	be	AUX
bptjm-41	8	28	�	�	PROPN
bptjm-41	8	29	rst	rst	PROPN
bptjm-41	8	30	described	describe	VERB
bptjm-41	8	31	by	by	ADP
bptjm-41	8	32	christian	christian	PROPN
bptjm-41	8	33	de	de	PROPN
bptjm-41	8	34	duve	duve	PROPN
bptjm-41	8	35	,	,	PUNCT
bptjm-41	8	36	who	who	PRON
bptjm-41	8	37	shared	share	VERB
bptjm-41	8	38	the	the	DET
bptjm-41	8	39	1974	1974	NUM
bptjm-41	8	40	nobel	nobel	PROPN
bptjm-41	8	41	prize	prize	PROPN
bptjm-41	8	42	for	for	ADP
bptjm-41	8	43	his	his	PRON
bptjm-41	8	44	discovery	discovery	NOUN
bptjm-41	8	45	of	of	ADP
bptjm-41	8	46	lysosomes	lysosome	NOUN
bptjm-41	8	47	.	.	PUNCT
bptjm-41	9	1	autophagy	autophagy	PROPN
bptjm-41	9	2	is	be	AUX
bptjm-41	9	3	an	an	DET
bptjm-41	9	4	evolutionarily	evolutionarily	ADV
bptjm-41	9	5	conserved	conserve	VERB
bptjm-41	9	6	catabolic	catabolic	ADJ
bptjm-41	9	7	process	process	NOUN
bptjm-41	9	8	wherein	wherein	ADJ
bptjm-41	9	9	lysosomes	lysosome	NOUN
bptjm-41	9	10	degrade	degrade	VERB
bptjm-41	9	11	various	various	ADJ
bptjm-41	9	12	cellular	cellular	ADJ
bptjm-41	9	13	components	component	NOUN
bptjm-41	9	14	to	to	PART
bptjm-41	9	15	maintain	maintain	VERB
bptjm-41	9	16	cytoplasmic	cytoplasmic	ADJ
bptjm-41	9	17	quality	quality	NOUN
bptjm-41	9	18	control	control	NOUN
bptjm-41	9	19	and	and	CCONJ
bptjm-41	9	20	thus	thus	ADV
bptjm-41	9	21	cellular	cellular	ADJ
bptjm-41	9	22	homeostasis	homeostasis	NOUN
bptjm-41	9	23	.	.	PUNCT
bptjm-41	10	1	several	several	ADJ
bptjm-41	10	2	distinct	distinct	ADJ
bptjm-41	10	3	forms	form	NOUN
bptjm-41	10	4	of	of	ADP
bptjm-41	10	5	autophagy	autophagy	NOUN
bptjm-41	10	6	include	include	VERB
bptjm-41	10	7	macroautophagy	macroautophagy	ADJ
bptjm-41	10	8	,	,	PUNCT
bptjm-41	10	9	microautophagy	microautophagy	ADJ
bptjm-41	10	10	,	,	PUNCT
bptjm-41	10	11	and	and	CCONJ
bptjm-41	10	12	chaperone	chaperone	NOUN
bptjm-41	10	13	-	-	PUNCT
bptjm-41	10	14	mediated	mediate	VERB
bptjm-41	10	15	autophagy	autophagy	NOUN
bptjm-41	10	16	(	(	PUNCT
bptjm-41	10	17	cma	cma	NOUN
bptjm-41	10	18	)	)	PUNCT
bptjm-41	10	19	.	.	PUNCT
bptjm-41	11	1	dysregulation	dysregulation	NOUN
bptjm-41	11	2	of	of	ADP
bptjm-41	11	3	this	this	DET
bptjm-41	11	4	critical	critical	ADJ
bptjm-41	11	5	process	process	NOUN
bptjm-41	11	6	has	have	AUX
bptjm-41	11	7	been	be	AUX
bptjm-41	11	8	associated	associate	VERB
bptjm-41	11	9	with	with	ADP
bptjm-41	11	10	many	many	ADJ
bptjm-41	11	11	pathological	pathological	ADJ
bptjm-41	11	12	processes	process	NOUN
bptjm-41	11	13	including	include	VERB
bptjm-41	11	14	infectious	infectious	ADJ
bptjm-41	11	15	,	,	PUNCT
bptjm-41	11	16	metabolic	metabolic	NOUN
bptjm-41	11	17	,	,	PUNCT
bptjm-41	11	18	and	and	CCONJ
bptjm-41	11	19	neurodegenerative	neurodegenerative	ADJ
bptjm-41	11	20	disorders	disorder	NOUN
bptjm-41	11	21	,	,	PUNCT
bptjm-41	11	22	as	as	ADV
bptjm-41	11	23	well	well	ADV
bptjm-41	11	24	as	as	ADP
bptjm-41	11	25	cancer	cancer	NOUN
bptjm-41	11	26	and	and	CCONJ
bptjm-41	11	27	autoimmunity	autoimmunity	NOUN
bptjm-41	11	28	.	.	PUNCT
bptjm-41	12	1	reduced	reduce	VERB
bptjm-41	12	2	autophagy	autophagy	NOUN
bptjm-41	12	3	was	be	AUX
bptjm-41	12	4	identi	identi	X
bptjm-41	12	5	�	�	PROPN
bptjm-41	12	6	ed	ed	NOUN
bptjm-41	12	7	by	by	ADP
bptjm-41	12	8	lópez	lópez	NOUN
bptjm-41	12	9	-	-	PUNCT
bptjm-41	12	10	otín	otín	NOUN
bptjm-41	12	11	et	et	PROPN
bptjm-41	12	12	al	al	PROPN
bptjm-41	12	13	.	.	PROPN
bptjm-41	13	1	(	(	PUNCT
bptjm-41	13	2	2013	2013	NUM
bptjm-41	13	3	)	)	PUNCT
bptjm-41	13	4	as	as	ADP
bptjm-41	13	5	a	a	DET
bptjm-41	13	6	so	so	ADV
bptjm-41	13	7	-	-	PUNCT
bptjm-41	13	8	called	call	VERB
bptjm-41	13	9	"	"	PUNCT
bptjm-41	13	10	hallmark	hallmark	NOUN
bptjm-41	13	11	of	of	ADP
bptjm-41	13	12	aging	age	VERB
bptjm-41	13	13	"	"	PUNCT
bptjm-41	13	14	.	.	PUNCT
bptjm-41	14	1	1.2	1.2	NUM
bptjm-41	14	2	chloroquine	chloroquine	ADJ
bptjm-41	14	3	native	native	ADJ
bptjm-41	14	4	peoples	people	NOUN
bptjm-41	14	5	of	of	ADP
bptjm-41	14	6	south	south	PROPN
bptjm-41	14	7	america	america	PROPN
bptjm-41	14	8	have	have	AUX
bptjm-41	14	9	long	long	ADV
bptjm-41	14	10	used	use	VERB
bptjm-41	14	11	an	an	DET
bptjm-41	14	12	extract	extract	NOUN
bptjm-41	14	13	of	of	ADP
bptjm-41	14	14	the	the	DET
bptjm-41	14	15	bark	bark	NOUN
bptjm-41	14	16	of	of	ADP
bptjm-41	14	17	the	the	DET
bptjm-41	14	18	cinchona	cinchona	NOUN
bptjm-41	14	19	tree	tree	NOUN
bptjm-41	14	20	(	(	PUNCT
bptjm-41	14	21	cinchona	cinchona	PROPN
bptjm-41	14	22	officinalis	officinalis	PROPN
bptjm-41	14	23	)	)	PUNCT
bptjm-41	14	24	as	as	ADP
bptjm-41	14	25	a	a	DET
bptjm-41	14	26	remedy	remedy	NOUN
bptjm-41	14	27	for	for	ADP
bptjm-41	14	28	fevers	fever	NOUN
bptjm-41	14	29	.	.	PUNCT
bptjm-41	15	1	by	by	ADP
bptjm-41	15	2	the	the	DET
bptjm-41	15	3	1600s	1600	NOUN
bptjm-41	15	4	,	,	PUNCT
bptjm-41	15	5	this	this	DET
bptjm-41	15	6	herbal	herbal	ADJ
bptjm-41	15	7	medicine	medicine	NOUN
bptjm-41	15	8	was	be	AUX
bptjm-41	15	9	being	be	AUX
bptjm-41	15	10	used	use	VERB
bptjm-41	15	11	in	in	ADP
bptjm-41	15	12	europe	europe	PROPN
bptjm-41	15	13	for	for	ADP
bptjm-41	15	14	treatment	treatment	NOUN
bptjm-41	15	15	of	of	ADP
bptjm-41	15	16	malaria	malaria	NOUN
bptjm-41	15	17	.	.	PUNCT
bptjm-41	16	1	quinine	quinine	PROPN
bptjm-41	16	2	was	be	AUX
bptjm-41	16	3	isolated	isolate	VERB
bptjm-41	16	4	from	from	ADP
bptjm-41	16	5	the	the	DET
bptjm-41	16	6	bark	bark	NOUN
bptjm-41	16	7	in	in	ADP
bptjm-41	16	8	1820	1820	NUM
bptjm-41	16	9	.	.	PUNCT
bptjm-41	17	1	seeking	seek	VERB
bptjm-41	17	2	an	an	DET
bptjm-41	17	3	alternative	alternative	NOUN
bptjm-41	17	4	to	to	ADP
bptjm-41	17	5	quinine	quinine	NOUN
bptjm-41	17	6	,	,	PUNCT
bptjm-41	17	7	bayer	bayer	NOUN
bptjm-41	17	8	chemists	chemist	NOUN
bptjm-41	17	9	discovered	discover	VERB
bptjm-41	17	10	chloroquine	chloroquine	NOUN
bptjm-41	17	11	,	,	PUNCT
bptjm-41	17	12	a	a	DET
bptjm-41	17	13	synthetic	synthetic	ADJ
bptjm-41	17	14	analog	analog	NOUN
bptjm-41	17	15	with	with	ADP
bptjm-41	17	16	a	a	DET
bptjm-41	17	17	similar	similar	ADJ
bptjm-41	17	18	mechanism	mechanism	NOUN
bptjm-41	17	19	of	of	ADP
bptjm-41	17	20	action	action	NOUN
bptjm-41	17	21	.	.	PUNCT
bptjm-41	18	1	a	a	DET
bptjm-41	18	2	related	related	ADJ
bptjm-41	18	3	analogue	analogue	NOUN
bptjm-41	18	4	,	,	PUNCT
bptjm-41	18	5	3	3	NUM
bptjm-41	18	6	-	-	PUNCT
bptjm-41	18	7	methyl	methyl	NOUN
bptjm-41	18	8	-	-	PUNCT
bptjm-41	18	9	chloroquine	chloroquine	NOUN
bptjm-41	18	10	,	,	PUNCT
bptjm-41	18	11	was	be	AUX
bptjm-41	18	12	utilized	utilize	VERB
bptjm-41	18	13	by	by	ADP
bptjm-41	18	14	the	the	DET
bptjm-41	18	15	germans	germans	PROPN
bptjm-41	18	16	in	in	ADP
bptjm-41	18	17	world	world	PROPN
bptjm-41	18	18	war	war	PROPN
bptjm-41	18	19	ii	ii	PROPN
bptjm-41	18	20	.	.	PUNCT
bptjm-41	19	1	material	material	PROPN
bptjm-41	19	2	captured	capture	VERB
bptjm-41	19	3	by	by	ADP
bptjm-41	19	4	the	the	DET
bptjm-41	19	5	americans	americans	PROPN
bptjm-41	19	6	in	in	ADP
bptjm-41	19	7	north	north	PROPN
bptjm-41	19	8	africa	africa	PROPN
bptjm-41	19	9	was	be	AUX
bptjm-41	19	10	analyzed	analyze	VERB
bptjm-41	19	11	by	by	ADP
bptjm-41	19	12	the	the	DET
bptjm-41	19	13	united	united	PROPN
bptjm-41	19	14	states	states	PROPN
bptjm-41	19	15	government	government	NOUN
bptjm-41	19	16	,	,	PUNCT
bptjm-41	19	17	resulting	result	VERB
bptjm-41	19	18	in	in	ADP
bptjm-41	19	19	corroborative	corroborative	ADJ
bptjm-41	19	20	studies	study	NOUN
bptjm-41	19	21	and	and	CCONJ
bptjm-41	19	22	subsequent	subsequent	ADJ
bptjm-41	19	23	clinical	clinical	ADJ
bptjm-41	19	24	approval	approval	NOUN
bptjm-41	19	25	in	in	ADP
bptjm-41	19	26	1947	1947	NUM
bptjm-41	19	27	of	of	ADP
bptjm-41	19	28	chloroquine	chloroquine	NOUN
bptjm-41	19	29	as	as	ADP
bptjm-41	19	30	a	a	DET
bptjm-41	19	31	prophylactic	prophylactic	ADJ
bptjm-41	19	32	treatment	treatment	NOUN
bptjm-41	19	33	for	for	ADP
bptjm-41	19	34	malaria	malaria	NOUN
bptjm-41	19	35	.	.	PUNCT
bptjm-41	20	1	while	while	SCONJ
bptjm-41	20	2	chloroquine	chloroquine	NOUN
bptjm-41	20	3	and	and	CCONJ
bptjm-41	20	4	its	its	PRON
bptjm-41	20	5	derivative	derivative	ADJ
bptjm-41	20	6	hydroxychloroquine	hydroxychloroquine	NOUN
bptjm-41	20	7	are	be	AUX
bptjm-41	20	8	widely	widely	ADV
bptjm-41	20	9	used	use	VERB
bptjm-41	20	10	in	in	ADP
bptjm-41	20	11	rheumatology	rheumatology	NOUN
bptjm-41	20	12	(	(	PUNCT
bptjm-41	20	13	sle	sle	PROPN
bptjm-41	20	14	,	,	PUNCT
bptjm-41	20	15	ra	ra	PROPN
bptjm-41	20	16	,	,	PUNCT
bptjm-41	20	17	etc	etc	X
bptjm-41	20	18	.	.	X
bptjm-41	20	19	)	)	PUNCT
bptjm-41	20	20	1	1	NUM
bptjm-41	20	21	,	,	PUNCT
bptjm-41	20	22	chloroquine	chloroquine	NOUN
bptjm-41	20	23	-	-	PUNCT
bptjm-41	20	24	resistant	resistant	ADJ
bptjm-41	20	25	malaria	malaria	NOUN
bptjm-41	20	26	has	have	AUX
bptjm-41	20	27	mandated	mandate	VERB
bptjm-41	20	28	the	the	DET
bptjm-41	20	29	development	development	NOUN
bptjm-41	20	30	of	of	ADP
bptjm-41	20	31	newer	new	ADJ
bptjm-41	20	32	antimalarials	antimalarial	NOUN
bptjm-41	20	33	such	such	ADJ
bptjm-41	20	34	as	as	ADP
bptjm-41	20	35	pyrimethamine	pyrimethamine	NOUN
bptjm-41	20	36	,	,	PUNCT
bptjm-41	20	37	artemisinin	artemisinin	PROPN
bptjm-41	20	38	and	and	CCONJ
bptjm-41	20	39	me	i	PRON
bptjm-41	20	40	�	�	PROPN
bptjm-41	20	41	oquine	oquine	ADJ
bptjm-41	20	42	2	2	NUM
bptjm-41	20	43	.	.	PUNCT
bptjm-41	21	1	chloroquine	chloroquine	PROPN
bptjm-41	21	2	inhibits	inhibit	VERB
bptjm-41	21	3	hemozoin	hemozoin	NOUN
bptjm-41	21	4	formation	formation	NOUN
bptjm-41	21	5	from	from	ADP
bptjm-41	21	6	the	the	DET
bptjm-41	21	7	heme	heme	NOUN
bptjm-41	21	8	released	release	VERB
bptjm-41	21	9	by	by	ADP
bptjm-41	21	10	parasitic	parasitic	ADJ
bptjm-41	21	11	digestion	digestion	NOUN
bptjm-41	21	12	of	of	ADP
bptjm-41	21	13	erythrocyte	erythrocyte	ADJ
bptjm-41	21	14	hemoglobin	hemoglobin	NOUN
bptjm-41	21	15	during	during	ADP
bptjm-41	21	16	plasmodium	plasmodium	NOUN
bptjm-41	21	17	infection	infection	NOUN
bptjm-41	21	18	.	.	PUNCT
bptjm-41	22	1	the	the	DET
bptjm-41	22	2	free	free	ADJ
bptjm-41	22	3	heme	heme	NOUN
bptjm-41	22	4	then	then	ADV
bptjm-41	22	5	lyses	lyses	PROPN
bptjm-41	22	6	membranes	membrane	NOUN
bptjm-41	22	7	and	and	CCONJ
bptjm-41	22	8	leads	lead	VERB
bptjm-41	22	9	to	to	ADP
bptjm-41	22	10	parasite	parasite	ADJ
bptjm-41	22	11	death	death	NOUN
bptjm-41	22	12	3	3	NUM
bptjm-41	22	13	,	,	PUNCT
bptjm-41	22	14	4	4	NUM
bptjm-41	22	15	,	,	PUNCT
bptjm-41	22	16	5	5	NUM
bptjm-41	22	17	.	.	PUNCT
bptjm-41	23	1	chloroquine	chloroquine	PROPN
bptjm-41	23	2	passively	passively	ADV
bptjm-41	23	3	di	di	PROPN
bptjm-41	23	4	�	�	PROPN
bptjm-41	23	5	uses	use	VERB
bptjm-41	23	6	through	through	ADP
bptjm-41	23	7	cell	cell	NOUN
bptjm-41	23	8	membranes	membrane	NOUN
bptjm-41	23	9	and	and	CCONJ
bptjm-41	23	10	into	into	ADP
bptjm-41	23	11	berkeley	berkeley	PROPN
bptjm-41	23	12	pharma	pharma	PROPN
bptjm-41	23	13	tech	tech	NOUN
bptjm-41	23	14	journal	journal	NOUN
bptjm-41	23	15	of	of	ADP
bptjm-41	23	16	medicine	medicine	NOUN
bptjm-41	23	17	|	|	ADV
bptjm-41	23	18	2	2	NUM
bptjm-41	23	19	endosomes	endosome	NOUN
bptjm-41	23	20	,	,	PUNCT
bptjm-41	23	21	lysosomes	lysosome	NOUN
bptjm-41	23	22	,	,	PUNCT
bptjm-41	23	23	and	and	CCONJ
bptjm-41	23	24	golgi	golgi	NOUN
bptjm-41	23	25	vesicles	vesicle	NOUN
bptjm-41	23	26	which	which	PRON
bptjm-41	23	27	become	become	VERB
bptjm-41	23	28	protonated	protonate	VERB
bptjm-41	23	29	,	,	PUNCT
bptjm-41	23	30	trapping	trap	VERB
bptjm-41	23	31	the	the	DET
bptjm-41	23	32	chloroquine	chloroquine	NOUN
bptjm-41	23	33	in	in	ADP
bptjm-41	23	34	the	the	DET
bptjm-41	23	35	organelles	organelle	NOUN
bptjm-41	23	36	and	and	CCONJ
bptjm-41	23	37	raising	raise	VERB
bptjm-41	23	38	the	the	DET
bptjm-41	23	39	surrounding	surround	VERB
bptjm-41	23	40	ph	ph	NOUN
bptjm-41	23	41	.	.	PUNCT
bptjm-41	24	1	the	the	DET
bptjm-41	24	2	raised	raise	VERB
bptjm-41	24	3	ph	ph	NOUN
bptjm-41	24	4	in	in	ADP
bptjm-41	24	5	the	the	DET
bptjm-41	24	6	endosomal	endosomal	ADJ
bptjm-41	24	7	compartments	compartment	NOUN
bptjm-41	24	8	(	(	PUNCT
bptjm-41	24	9	a	a	DET
bptjm-41	24	10	so	so	ADV
bptjm-41	24	11	-	-	PUNCT
bptjm-41	24	12	called	call	VERB
bptjm-41	24	13	lysosomotropic	lysosomotropic	ADJ
bptjm-41	24	14	e	e	NOUN
bptjm-41	24	15	�	�	PROPN
bptjm-41	24	16	ect	ect	ADJ
bptjm-41	24	17	)	)	PUNCT
bptjm-41	24	18	,	,	PUNCT
bptjm-41	24	19	inhibits	inhibit	VERB
bptjm-41	24	20	viral	viral	ADJ
bptjm-41	24	21	infectivity	infectivity	NOUN
bptjm-41	24	22	and	and	CCONJ
bptjm-41	24	23	various	various	ADJ
bptjm-41	24	24	cellular	cellular	ADJ
bptjm-41	24	25	processes	process	NOUN
bptjm-41	24	26	such	such	ADJ
bptjm-41	24	27	as	as	ADP
bptjm-41	24	28	autophagy	autophagy	ADJ
bptjm-41	24	29	.	.	PUNCT
bptjm-41	25	1	geroprotective	geroprotective	ADJ
bptjm-41	25	2	activities	activity	NOUN
bptjm-41	25	3	of	of	ADP
bptjm-41	25	4	chloroquine	chloroquine	PROPN
bptjm-41	25	5	li	li	PROPN
bptjm-41	25	6	et	et	PROPN
bptjm-41	25	7	al	al	PROPN
bptjm-41	25	8	.	.	PROPN
bptjm-41	25	9	reported	report	VERB
bptjm-41	25	10	the	the	DET
bptjm-41	25	11	geroprotective	geroprotective	ADJ
bptjm-41	25	12	e	e	NOUN
bptjm-41	25	13	�	�	PROPN
bptjm-41	25	14	ects	ect	NOUN
bptjm-41	25	15	of	of	ADP
bptjm-41	25	16	low	low	ADV
bptjm-41	25	17	-	-	PUNCT
bptjm-41	25	18	dose	dose	NOUN
bptjm-41	25	19	cq	cq	NOUN
bptjm-41	25	20	on	on	ADP
bptjm-41	25	21	aged	aged	ADJ
bptjm-41	25	22	rats	rat	NOUN
bptjm-41	25	23	6	6	NUM
bptjm-41	25	24	.	.	PUNCT
bptjm-41	26	1	these	these	DET
bptjm-41	26	2	studies	study	NOUN
bptjm-41	26	3	were	be	AUX
bptjm-41	26	4	inspired	inspire	VERB
bptjm-41	26	5	by	by	ADP
bptjm-41	26	6	a	a	DET
bptjm-41	26	7	perspective	perspective	NOUN
bptjm-41	26	8	article	article	NOUN
bptjm-41	26	9	published	publish	VERB
bptjm-41	26	10	at	at	ADP
bptjm-41	26	11	the	the	DET
bptjm-41	26	12	height	height	NOUN
bptjm-41	26	13	of	of	ADP
bptjm-41	26	14	the	the	DET
bptjm-41	26	15	covid-19	covid-19	PROPN
bptjm-41	26	16	pandemic	pandemic	NOUN
bptjm-41	26	17	by	by	ADP
bptjm-41	26	18	sargiacomo	sargiacomo	NOUN
bptjm-41	26	19	et	et	PROPN
bptjm-41	26	20	al	al	PROPN
bptjm-41	26	21	.	.	PROPN
bptjm-41	27	1	in	in	ADP
bptjm-41	27	2	2020	2020	NUM
bptjm-41	27	3	7	7	NUM
bptjm-41	27	4	.	.	PUNCT
bptjm-41	28	1	this	this	DET
bptjm-41	28	2	british	british	ADJ
bptjm-41	28	3	group	group	NOUN
bptjm-41	28	4	sought	seek	VERB
bptjm-41	28	5	to	to	PART
bptjm-41	28	6	explain	explain	VERB
bptjm-41	28	7	the	the	DET
bptjm-41	28	8	considerably	considerably	ADV
bptjm-41	28	9	higher	high	ADJ
bptjm-41	28	10	mortality	mortality	NOUN
bptjm-41	28	11	rate	rate	NOUN
bptjm-41	28	12	in	in	ADP
bptjm-41	28	13	covid-19	covid-19	PROPN
bptjm-41	28	14	patients	patient	NOUN
bptjm-41	28	15	with	with	ADP
bptjm-41	28	16	advanced	advanced	ADJ
bptjm-41	28	17	chronological	chronological	ADJ
bptjm-41	28	18	age	age	NOUN
bptjm-41	28	19	prior	prior	ADV
bptjm-41	28	20	to	to	ADP
bptjm-41	28	21	the	the	DET
bptjm-41	28	22	development	development	NOUN
bptjm-41	28	23	of	of	ADP
bptjm-41	28	24	safe	safe	ADJ
bptjm-41	28	25	vaccines	vaccine	NOUN
bptjm-41	28	26	.	.	PUNCT
bptjm-41	29	1	they	they	PRON
bptjm-41	29	2	pointed	point	VERB
bptjm-41	29	3	out	out	ADP
bptjm-41	29	4	that	that	SCONJ
bptjm-41	29	5	the	the	DET
bptjm-41	29	6	proposed	propose	VERB
bptjm-41	29	7	sars	sar	NOUN
bptjm-41	29	8	-	-	PUNCT
bptjm-41	29	9	cov-2	cov-2	PART
bptjm-41	29	10	viral	viral	ADJ
bptjm-41	29	11	receptors	receptor	NOUN
bptjm-41	29	12	,	,	PUNCT
bptjm-41	29	13	cd26	cd26	PROPN
bptjm-41	29	14	and	and	CCONJ
bptjm-41	29	15	ace2	ace2	NOUN
bptjm-41	29	16	,	,	PUNCT
bptjm-41	29	17	were	be	AUX
bptjm-41	29	18	associated	associate	VERB
bptjm-41	29	19	with	with	ADP
bptjm-41	29	20	senescence	senescence	NOUN
bptjm-41	29	21	8	8	NUM
bptjm-41	29	22	,	,	PUNCT
bptjm-41	29	23	9	9	NUM
bptjm-41	29	24	.	.	PUNCT
bptjm-41	30	1	furthermore	furthermore	ADV
bptjm-41	30	2	,	,	PUNCT
bptjm-41	30	3	at	at	ADP
bptjm-41	30	4	the	the	DET
bptjm-41	30	5	time	time	NOUN
bptjm-41	30	6	,	,	PUNCT
bptjm-41	30	7	azithromycin	azithromycin	NOUN
bptjm-41	30	8	,	,	PUNCT
bptjm-41	30	9	quercetin	quercetin	NOUN
bptjm-41	30	10	,	,	PUNCT
bptjm-41	30	11	and	and	CCONJ
bptjm-41	30	12	hcq	hcq	NOUN
bptjm-41	30	13	were	be	AUX
bptjm-41	30	14	proposed	propose	VERB
bptjm-41	30	15	as	as	ADP
bptjm-41	30	16	"	"	PUNCT
bptjm-41	30	17	o	o	NOUN
bptjm-41	30	18	�	�	NOUN
bptjm-41	30	19	-the	-the	ADJ
bptjm-41	30	20	-	-	PUNCT
bptjm-41	30	21	shelf	shelf	NOUN
bptjm-41	30	22	"	"	PUNCT
bptjm-41	30	23	treatments	treatment	NOUN
bptjm-41	30	24	for	for	ADP
bptjm-41	30	25	sars	sar	NOUN
bptjm-41	30	26	-	-	PUNCT
bptjm-41	30	27	cov2	cov2	PROPN
bptjm-41	30	28	infection	infection	NOUN
bptjm-41	30	29	10	10	NUM
bptjm-41	30	30	.	.	PUNCT
bptjm-41	31	1	quercetin	quercetin	NOUN
bptjm-41	31	2	has	have	VERB
bptjm-41	31	3	a	a	DET
bptjm-41	31	4	senolytic	senolytic	ADJ
bptjm-41	31	5	activity	activity	NOUN
bptjm-41	31	6	11	11	NUM
bptjm-41	31	7	and	and	CCONJ
bptjm-41	31	8	hcq	hcq	NOUN
bptjm-41	31	9	is	be	AUX
bptjm-41	31	10	known	know	VERB
bptjm-41	31	11	to	to	PART
bptjm-41	31	12	inhibit	inhibit	VERB
bptjm-41	31	13	beta	beta	NOUN
bptjm-41	31	14	-	-	PUNCT
bptjm-41	31	15	galactosidase	galactosidase	NOUN
bptjm-41	31	16	,	,	PUNCT
bptjm-41	31	17	a	a	DET
bptjm-41	31	18	marker	marker	NOUN
bptjm-41	31	19	of	of	ADP
bptjm-41	31	20	senescence	senescence	NOUN
bptjm-41	31	21	12	12	NUM
bptjm-41	31	22	.	.	PUNCT
bptjm-41	32	1	although	although	SCONJ
bptjm-41	32	2	early	early	ADJ
bptjm-41	32	3	and	and	CCONJ
bptjm-41	32	4	questionable	questionable	ADJ
bptjm-41	32	5	trials	trial	NOUN
bptjm-41	32	6	demonstrated	demonstrate	VERB
bptjm-41	32	7	some	some	DET
bptjm-41	32	8	bene	bene	PROPN
bptjm-41	32	9	�	�	PROPN
bptjm-41	32	10	t	t	PROPN
bptjm-41	32	11	of	of	ADP
bptjm-41	32	12	hcq	hcq	PROPN
bptjm-41	32	13	13	13	NUM
bptjm-41	32	14	for	for	ADP
bptjm-41	32	15	sars	sar	NOUN
bptjm-41	32	16	-	-	PUNCT
bptjm-41	32	17	cov2	cov2	PROPN
bptjm-41	32	18	,	,	PUNCT
bptjm-41	32	19	subsequent	subsequent	ADJ
bptjm-41	32	20	well	well	ADV
bptjm-41	32	21	-	-	PUNCT
bptjm-41	32	22	controlled	control	VERB
bptjm-41	32	23	trials	trial	NOUN
bptjm-41	32	24	demonstrated	demonstrate	VERB
bptjm-41	32	25	limited	limited	ADJ
bptjm-41	32	26	,	,	PUNCT
bptjm-41	32	27	if	if	SCONJ
bptjm-41	32	28	any	any	DET
bptjm-41	32	29	,	,	PUNCT
bptjm-41	32	30	bene	bene	PROPN
bptjm-41	32	31	�	�	PROPN
bptjm-41	32	32	t	t	PROPN
bptjm-41	32	33	14	14	NUM
bptjm-41	32	34	,	,	PUNCT
bptjm-41	32	35	15	15	NUM
bptjm-41	32	36	.	.	PUNCT
bptjm-41	33	1	however	however	ADV
bptjm-41	33	2	,	,	PUNCT
bptjm-41	33	3	it	it	PRON
bptjm-41	33	4	is	be	AUX
bptjm-41	33	5	important	important	ADJ
bptjm-41	33	6	to	to	PART
bptjm-41	33	7	note	note	VERB
bptjm-41	33	8	that	that	SCONJ
bptjm-41	33	9	investigation	investigation	NOUN
bptjm-41	33	10	of	of	ADP
bptjm-41	33	11	the	the	DET
bptjm-41	33	12	role	role	NOUN
bptjm-41	33	13	of	of	ADP
bptjm-41	33	14	the	the	DET
bptjm-41	33	15	autophagy	autophagy	ADJ
bptjm-41	33	16	pathway	pathway	NOUN
bptjm-41	33	17	in	in	ADP
bptjm-41	33	18	viral	viral	ADJ
bptjm-41	33	19	pathogenesis	pathogenesis	NOUN
bptjm-41	33	20	continues	continue	VERB
bptjm-41	33	21	16	16	NUM
bptjm-41	33	22	.	.	PUNCT
bptjm-41	34	1	to	to	PART
bptjm-41	34	2	investigate	investigate	VERB
bptjm-41	34	3	the	the	DET
bptjm-41	34	4	geroprotective	geroprotective	ADJ
bptjm-41	34	5	e	e	NOUN
bptjm-41	34	6	�	�	PROPN
bptjm-41	34	7	ects	ect	NOUN
bptjm-41	34	8	of	of	ADP
bptjm-41	34	9	hcq	hcq	NOUN
bptjm-41	34	10	,	,	PUNCT
bptjm-41	34	11	li	li	PROPN
bptjm-41	34	12	et	et	PROPN
bptjm-41	34	13	al	al	PROPN
bptjm-41	34	14	.	.	PROPN
bptjm-41	34	15	treated	treat	VERB
bptjm-41	34	16	24	24	NUM
bptjm-41	34	17	-	-	PUNCT
bptjm-41	34	18	month	month	NOUN
bptjm-41	34	19	-	-	PUNCT
bptjm-41	34	20	old	old	ADJ
bptjm-41	34	21	sprague	sprague	NOUN
bptjm-41	34	22	dawley	dawley	ADJ
bptjm-41	34	23	male	male	ADJ
bptjm-41	34	24	rats	rat	NOUN
bptjm-41	34	25	(	(	PUNCT
bptjm-41	34	26	n	n	NOUN
bptjm-41	34	27	=	=	SYM
bptjm-41	34	28	9	9	NUM
bptjm-41	34	29	)	)	PUNCT
bptjm-41	34	30	with	with	ADP
bptjm-41	34	31	cq	cq	PROPN
bptjm-41	34	32	(	(	PUNCT
bptjm-41	34	33	0.1	0.1	NUM
bptjm-41	34	34	mg	mg	PROPN
bptjm-41	34	35	/	/	SYM
bptjm-41	34	36	kg	kg	PROPN
bptjm-41	34	37	,	,	PUNCT
bptjm-41	34	38	in	in	ADP
bptjm-41	34	39	drinking	drinking	NOUN
bptjm-41	34	40	water	water	NOUN
bptjm-41	34	41	)	)	PUNCT
bptjm-41	34	42	twice	twice	ADV
bptjm-41	34	43	weekly	weekly	ADV
bptjm-41	34	44	for	for	ADP
bptjm-41	34	45	5	5	NUM
bptjm-41	34	46	months	month	NOUN
bptjm-41	34	47	6	6	NUM
bptjm-41	34	48	.	.	PUNCT
bptjm-41	35	1	compared	compare	VERB
bptjm-41	35	2	to	to	ADP
bptjm-41	35	3	controls	control	NOUN
bptjm-41	35	4	(	(	PUNCT
bptjm-41	35	5	n	n	NOUN
bptjm-41	35	6	=	=	SYM
bptjm-41	35	7	13	13	NUM
bptjm-41	35	8	)	)	PUNCT
bptjm-41	35	9	,	,	PUNCT
bptjm-41	35	10	the	the	DET
bptjm-41	35	11	treated	treat	VERB
bptjm-41	35	12	animals	animal	NOUN
bptjm-41	35	13	exhibited	exhibit	VERB
bptjm-41	35	14	a	a	DET
bptjm-41	35	15	6	6	NUM
bptjm-41	35	16	%	%	NOUN
bptjm-41	35	17	increase	increase	NOUN
bptjm-41	35	18	in	in	ADP
bptjm-41	35	19	medial	medial	ADJ
bptjm-41	35	20	survival	survival	NOUN
bptjm-41	35	21	and	and	CCONJ
bptjm-41	35	22	13	13	NUM
bptjm-41	35	23	%	%	NOUN
bptjm-41	35	24	increase	increase	NOUN
bptjm-41	35	25	in	in	ADP
bptjm-41	35	26	maximum	maximum	ADJ
bptjm-41	35	27	lifespan	lifespan	NOUN
bptjm-41	35	28	(	(	PUNCT
bptjm-41	35	29	p	p	NOUN
bptjm-41	35	30	=	=	NOUN
bptjm-41	35	31	0.02	0.02	NUM
bptjm-41	35	32	)	)	PUNCT
bptjm-41	35	33	6	6	NUM
bptjm-41	35	34	.	.	PUNCT
bptjm-41	36	1	related	relate	VERB
bptjm-41	36	2	to	to	ADP
bptjm-41	36	3	the	the	DET
bptjm-41	36	4	work	work	NOUN
bptjm-41	36	5	of	of	ADP
bptjm-41	36	6	li	li	PROPN
bptjm-41	36	7	et	et	PROPN
bptjm-41	36	8	al	al	PROPN
bptjm-41	36	9	.	.	PROPN
bptjm-41	36	10	,	,	PUNCT
bptjm-41	36	11	doeppner	doeppner	NOUN
bptjm-41	36	12	et	et	PROPN
bptjm-41	36	13	al	al	PROPN
bptjm-41	36	14	.	.	PROPN
bptjm-41	37	1	(	(	PUNCT
bptjm-41	37	2	2022	2022	NUM
bptjm-41	37	3	)	)	PUNCT
bptjm-41	37	4	also	also	ADV
bptjm-41	37	5	reported	report	VERB
bptjm-41	37	6	a	a	DET
bptjm-41	37	7	chloroquine	chloroquine	NOUN
bptjm-41	37	8	-	-	PUNCT
bptjm-41	37	9	mediated	mediate	VERB
bptjm-41	37	10	increase	increase	NOUN
bptjm-41	37	11	in	in	ADP
bptjm-41	37	12	the	the	DET
bptjm-41	37	13	lifespan	lifespan	NOUN
bptjm-41	37	14	of	of	ADP
bptjm-41	37	15	rodents	rodent	NOUN
bptjm-41	37	16	,	,	PUNCT
bptjm-41	37	17	in	in	ADP
bptjm-41	37	18	this	this	DET
bptjm-41	37	19	case	case	NOUN
bptjm-41	37	20	mice	mice	VERB
bptjm-41	37	21	17	17	NUM
bptjm-41	37	22	.	.	PUNCT
bptjm-41	38	1	work	work	NOUN
bptjm-41	38	2	by	by	ADP
bptjm-41	38	3	fifan	fifan	PROPN
bptjm-41	38	4	et	et	PROPN
bptjm-41	38	5	al	al	PROPN
bptjm-41	38	6	.	.	PROPN
bptjm-41	38	7	18	18	NUM
bptjm-41	38	8	and	and	CCONJ
bptjm-41	38	9	others	other	NOUN
bptjm-41	38	10	19	19	NUM
bptjm-41	38	11	,	,	PUNCT
bptjm-41	38	12	20	20	NUM
bptjm-41	38	13	demonstrated	demonstrate	VERB
bptjm-41	38	14	that	that	SCONJ
bptjm-41	38	15	the	the	DET
bptjm-41	38	16	polyamine	polyamine	NOUN
bptjm-41	38	17	spermidine	spermidine	NOUN
bptjm-41	38	18	increased	increase	VERB
bptjm-41	38	19	the	the	DET
bptjm-41	38	20	maximum	maximum	ADJ
bptjm-41	38	21	life	life	NOUN
bptjm-41	38	22	span	span	NOUN
bptjm-41	38	23	of	of	ADP
bptjm-41	38	24	c.	c.	PROPN
bptjm-41	38	25	elegans	elegan	NOUN
bptjm-41	38	26	and	and	CCONJ
bptjm-41	38	27	the	the	DET
bptjm-41	38	28	median	median	ADJ
bptjm-41	38	29	life	life	NOUN
bptjm-41	38	30	span	span	NOUN
bptjm-41	38	31	of	of	ADP
bptjm-41	38	32	mice	mouse	NOUN
bptjm-41	38	33	(	(	PUNCT
bptjm-41	38	34	~10	~10	NOUN
bptjm-41	38	35	%	%	NOUN
bptjm-41	38	36	)	)	PUNCT
bptjm-41	38	37	.	.	PUNCT
bptjm-41	39	1	because	because	SCONJ
bptjm-41	39	2	spermidine	spermidine	NOUN
bptjm-41	39	3	increases	increase	NOUN
bptjm-41	39	4	autophagy	autophagy	VERB
bptjm-41	39	5	,	,	PUNCT
bptjm-41	39	6	they	they	PRON
bptjm-41	39	7	hypothesized	hypothesize	VERB
bptjm-41	39	8	that	that	SCONJ
bptjm-41	39	9	treatment	treatment	NOUN
bptjm-41	39	10	with	with	ADP
bptjm-41	39	11	chloroquine	chloroquine	NOUN
bptjm-41	39	12	,	,	PUNCT
bptjm-41	39	13	an	an	DET
bptjm-41	39	14	inhibitor	inhibitor	NOUN
bptjm-41	39	15	of	of	ADP
bptjm-41	39	16	autophagy	autophagy	NOUN
bptjm-41	39	17	,	,	PUNCT
bptjm-41	39	18	would	would	AUX
bptjm-41	39	19	shorten	shorten	VERB
bptjm-41	39	20	the	the	DET
bptjm-41	39	21	lifespan	lifespan	NOUN
bptjm-41	39	22	of	of	ADP
bptjm-41	39	23	mice	mouse	NOUN
bptjm-41	39	24	.	.	PUNCT
bptjm-41	40	1	remarkably	remarkably	ADV
bptjm-41	40	2	,	,	PUNCT
bptjm-41	40	3	addition	addition	NOUN
bptjm-41	40	4	of	of	ADP
bptjm-41	40	5	chloroquine	chloroquine	NOUN
bptjm-41	40	6	(	(	PUNCT
bptjm-41	40	7	50	50	NUM
bptjm-41	40	8	mg	mg	PROPN
bptjm-41	40	9	/	/	SYM
bptjm-41	40	10	kg	kg	NOUN
bptjm-41	40	11	)	)	PUNCT
bptjm-41	40	12	to	to	ADP
bptjm-41	40	13	the	the	DET
bptjm-41	40	14	drinking	drinking	NOUN
bptjm-41	40	15	water	water	NOUN
bptjm-41	40	16	extended	extend	VERB
bptjm-41	40	17	overall	overall	ADJ
bptjm-41	40	18	lifespan	lifespan	NOUN
bptjm-41	40	19	of	of	ADP
bptjm-41	40	20	middle	middle	NOUN
bptjm-41	40	21	-	-	PUNCT
bptjm-41	40	22	aged	aged	ADJ
bptjm-41	40	23	berkeley	berkeley	PROPN
bptjm-41	40	24	pharma	pharma	PROPN
bptjm-41	40	25	tech	tech	NOUN
bptjm-41	40	26	journal	journal	NOUN
bptjm-41	40	27	of	of	ADP
bptjm-41	40	28	medicine	medicine	NOUN
bptjm-41	40	29	|	|	ADV
bptjm-41	40	30	3	3	NUM
bptjm-41	40	31	male	male	ADJ
bptjm-41	40	32	nmri	nmri	ADJ
bptjm-41	40	33	mice	mouse	NOUN
bptjm-41	40	34	(	(	PUNCT
bptjm-41	40	35	n	n	NOUN
bptjm-41	40	36	=	=	SYM
bptjm-41	40	37	28	28	NUM
bptjm-41	40	38	;	;	PUNCT
bptjm-41	40	39	treatment	treatment	NOUN
bptjm-41	40	40	initiated	initiate	VERB
bptjm-41	40	41	at	at	ADP
bptjm-41	40	42	age	age	NOUN
bptjm-41	40	43	500	500	NUM
bptjm-41	40	44	days	day	NOUN
bptjm-41	40	45	)	)	PUNCT
bptjm-41	40	46	by	by	ADP
bptjm-41	40	47	11.4	11.4	NUM
bptjm-41	40	48	%	%	NOUN
bptjm-41	40	49	(	(	PUNCT
bptjm-41	40	50	786	786	NUM
bptjm-41	40	51	days	day	NOUN
bptjm-41	40	52	)	)	PUNCT
bptjm-41	40	53	compared	compare	VERB
bptjm-41	40	54	to	to	PART
bptjm-41	40	55	control	control	VERB
bptjm-41	40	56	mice	mouse	NOUN
bptjm-41	40	57	(	(	PUNCT
bptjm-41	40	58	n	n	NOUN
bptjm-41	40	59	=	=	SYM
bptjm-41	40	60	28	28	NUM
bptjm-41	40	61	;	;	PUNCT
bptjm-41	40	62	689	689	NUM
bptjm-41	40	63	days	day	NOUN
bptjm-41	40	64	,	,	PUNCT
bptjm-41	40	65	p	p	NOUN
bptjm-41	40	66	=	=	PROPN
bptjm-41	40	67	0.0002	0.0002	NUM
bptjm-41	40	68	)	)	PUNCT
bptjm-41	40	69	.	.	PUNCT
bptjm-41	41	1	median	median	ADJ
bptjm-41	41	2	life	life	NOUN
bptjm-41	41	3	span	span	NOUN
bptjm-41	41	4	of	of	ADP
bptjm-41	41	5	the	the	DET
bptjm-41	41	6	middle	middle	ADJ
bptjm-41	41	7	-	-	PUNCT
bptjm-41	41	8	aged	aged	ADJ
bptjm-41	41	9	mice	mouse	NOUN
bptjm-41	41	10	increased	increase	VERB
bptjm-41	41	11	by	by	ADP
bptjm-41	41	12	11.4	11.4	NUM
bptjm-41	41	13	%	%	NOUN
bptjm-41	41	14	.	.	PUNCT
bptjm-41	42	1	studies	study	NOUN
bptjm-41	42	2	of	of	ADP
bptjm-41	42	3	chloroquine	chloroquine	NOUN
bptjm-41	42	4	by	by	ADP
bptjm-41	42	5	these	these	DET
bptjm-41	42	6	two	two	NUM
bptjm-41	42	7	groups	group	NOUN
bptjm-41	42	8	and	and	CCONJ
bptjm-41	42	9	other	other	ADJ
bptjm-41	42	10	data	datum	NOUN
bptjm-41	42	11	dating	date	VERB
bptjm-41	42	12	back	back	ADV
bptjm-41	42	13	a	a	DET
bptjm-41	42	14	couple	couple	NOUN
bptjm-41	42	15	decades	decade	NOUN
bptjm-41	42	16	suggest	suggest	VERB
bptjm-41	42	17	the	the	DET
bptjm-41	42	18	e	e	NOUN
bptjm-41	42	19	�	�	NOUN
bptjm-41	42	20	ect	ect	VERB
bptjm-41	42	21	is	be	AUX
bptjm-41	42	22	real	real	ADJ
bptjm-41	42	23	,	,	PUNCT
bptjm-41	42	24	although	although	SCONJ
bptjm-41	42	25	the	the	DET
bptjm-41	42	26	precise	precise	ADJ
bptjm-41	42	27	mechanism	mechanism	NOUN
bptjm-41	42	28	is	be	AUX
bptjm-41	42	29	not	not	PART
bptjm-41	42	30	clear	clear	ADJ
bptjm-41	42	31	.	.	PUNCT
bptjm-41	43	1	mechanistic	mechanistic	ADJ
bptjm-41	43	2	studies	study	NOUN
bptjm-41	43	3	carried	carry	VERB
bptjm-41	43	4	out	out	ADP
bptjm-41	43	5	by	by	ADP
bptjm-41	43	6	both	both	DET
bptjm-41	43	7	groups	group	NOUN
bptjm-41	43	8	suggest	suggest	VERB
bptjm-41	43	9	a	a	DET
bptjm-41	43	10	variety	variety	NOUN
bptjm-41	43	11	of	of	ADP
bptjm-41	43	12	mechanisms	mechanism	NOUN
bptjm-41	43	13	,	,	PUNCT
bptjm-41	43	14	though	though	SCONJ
bptjm-41	43	15	this	this	DET
bptjm-41	43	16	"	"	PUNCT
bptjm-41	43	17	ball	ball	NOUN
bptjm-41	43	18	of	of	ADP
bptjm-41	43	19	yarn	yarn	NOUN
bptjm-41	43	20	"	"	PUNCT
bptjm-41	43	21	is	be	AUX
bptjm-41	43	22	far	far	ADV
bptjm-41	43	23	from	from	ADP
bptjm-41	43	24	being	be	AUX
bptjm-41	43	25	unraveled	unravel	VERB
bptjm-41	43	26	.	.	PUNCT
bptjm-41	44	1	mechanism	mechanism	NOUN
bptjm-41	44	2	studies	study	NOUN
bptjm-41	44	3	as	as	SCONJ
bptjm-41	44	4	noted	note	VERB
bptjm-41	44	5	above	above	ADV
bptjm-41	44	6	,	,	PUNCT
bptjm-41	44	7	cq	cq	NOUN
bptjm-41	44	8	treatment	treatment	NOUN
bptjm-41	44	9	was	be	AUX
bptjm-41	44	10	initiated	initiate	VERB
bptjm-41	44	11	at	at	ADP
bptjm-41	44	12	age	age	NOUN
bptjm-41	44	13	500	500	NUM
bptjm-41	44	14	days	day	NOUN
bptjm-41	44	15	when	when	SCONJ
bptjm-41	44	16	the	the	DET
bptjm-41	44	17	mice	mouse	NOUN
bptjm-41	44	18	weighed	weigh	VERB
bptjm-41	44	19	on	on	ADV
bptjm-41	44	20	average	average	ADJ
bptjm-41	44	21	~35	~35	ADP
bptjm-41	44	22	gm	gm	PROPN
bptjm-41	44	23	.	.	PUNCT
bptjm-41	45	1	over	over	ADP
bptjm-41	45	2	the	the	DET
bptjm-41	45	3	next	next	ADJ
bptjm-41	45	4	100	100	NUM
bptjm-41	45	5	days	day	NOUN
bptjm-41	45	6	,	,	PUNCT
bptjm-41	45	7	the	the	DET
bptjm-41	45	8	control	control	NOUN
bptjm-41	45	9	animals	animal	NOUN
bptjm-41	45	10	gained	gain	VERB
bptjm-41	45	11	weight	weight	NOUN
bptjm-41	45	12	,	,	PUNCT
bptjm-41	45	13	reaching	reach	VERB
bptjm-41	45	14	a	a	DET
bptjm-41	45	15	maximum	maximum	NOUN
bptjm-41	45	16	of	of	ADP
bptjm-41	45	17	45	45	NUM
bptjm-41	45	18	gm	gm	PROPN
bptjm-41	45	19	.	.	PUNCT
bptjm-41	46	1	in	in	ADP
bptjm-41	46	2	contrast	contrast	NOUN
bptjm-41	46	3	,	,	PUNCT
bptjm-41	46	4	the	the	DET
bptjm-41	46	5	cq	cq	NOUN
bptjm-41	46	6	-	-	PUNCT
bptjm-41	46	7	treated	treat	VERB
bptjm-41	46	8	animals	animal	NOUN
bptjm-41	46	9	did	do	AUX
bptjm-41	46	10	not	not	PART
bptjm-41	46	11	gain	gain	VERB
bptjm-41	46	12	signi	signi	ADJ
bptjm-41	46	13	�	�	NOUN
bptjm-41	46	14	cant	cant	VERB
bptjm-41	46	15	weight	weight	NOUN
bptjm-41	46	16	over	over	ADP
bptjm-41	46	17	the	the	DET
bptjm-41	46	18	duration	duration	NOUN
bptjm-41	46	19	of	of	ADP
bptjm-41	46	20	the	the	DET
bptjm-41	46	21	experiment	experiment	NOUN
bptjm-41	46	22	(	(	PUNCT
bptjm-41	46	23	almost	almost	ADV
bptjm-41	46	24	800	800	NUM
bptjm-41	46	25	days	day	NOUN
bptjm-41	46	26	)	)	PUNCT
bptjm-41	46	27	.	.	PUNCT
bptjm-41	47	1	while	while	SCONJ
bptjm-41	47	2	the	the	DET
bptjm-41	47	3	control	control	NOUN
bptjm-41	47	4	animals	animal	NOUN
bptjm-41	47	5	consumed	consume	VERB
bptjm-41	47	6	more	more	ADJ
bptjm-41	47	7	liquid	liquid	ADJ
bptjm-41	47	8	(	(	PUNCT
bptjm-41	47	9	p	p	NOUN
bptjm-41	47	10	=	=	NOUN
bptjm-41	47	11	0.002	0.002	NUM
bptjm-41	47	12	)	)	PUNCT
bptjm-41	47	13	,	,	PUNCT
bptjm-41	47	14	the	the	DET
bptjm-41	47	15	food	food	NOUN
bptjm-41	47	16	consumed	consume	VERB
bptjm-41	47	17	by	by	ADP
bptjm-41	47	18	both	both	DET
bptjm-41	47	19	groups	group	NOUN
bptjm-41	47	20	was	be	AUX
bptjm-41	47	21	equal	equal	ADJ
bptjm-41	47	22	(	(	PUNCT
bptjm-41	47	23	~4	~4	NOUN
bptjm-41	47	24	gm	gm	PROPN
bptjm-41	47	25	/	/	SYM
bptjm-41	47	26	day	day	NOUN
bptjm-41	47	27	)	)	PUNCT
bptjm-41	47	28	ruling	rule	VERB
bptjm-41	47	29	out	out	ADP
bptjm-41	47	30	the	the	DET
bptjm-41	47	31	idea	idea	NOUN
bptjm-41	47	32	that	that	PRON
bptjm-41	47	33	cq	cq	INTJ
bptjm-41	47	34	somehow	somehow	ADV
bptjm-41	47	35	reduced	reduce	VERB
bptjm-41	47	36	food	food	NOUN
bptjm-41	47	37	intake	intake	NOUN
bptjm-41	47	38	through	through	ADP
bptjm-41	47	39	an	an	DET
bptjm-41	47	40	arti	arti	PROPN
bptjm-41	47	41	�	�	PROPN
bptjm-41	47	42	cial	cial	ADJ
bptjm-41	47	43	"	"	PUNCT
bptjm-41	47	44	calorie	calorie	NOUN
bptjm-41	47	45	restriction	restriction	NOUN
bptjm-41	47	46	"	"	PUNCT
bptjm-41	47	47	e	e	NOUN
bptjm-41	47	48	�	�	NOUN
bptjm-41	47	49	ect	ect	NOUN
bptjm-41	47	50	.	.	PUNCT
bptjm-41	48	1	previously	previously	ADV
bptjm-41	48	2	,	,	PUNCT
bptjm-41	48	3	cq	cq	PROPN
bptjm-41	48	4	(	(	PUNCT
bptjm-41	48	5	at	at	ADP
bptjm-41	48	6	60	60	NUM
bptjm-41	48	7	mg	mg	NUM
bptjm-41	48	8	/	/	SYM
bptjm-41	48	9	kg	kg	PROPN
bptjm-41	48	10	)	)	PUNCT
bptjm-41	48	11	was	be	AUX
bptjm-41	48	12	reported	report	VERB
bptjm-41	48	13	to	to	PART
bptjm-41	48	14	impair	impair	VERB
bptjm-41	48	15	autophagosome	autophagosome	NOUN
bptjm-41	48	16	-	-	PUNCT
bptjm-41	48	17	lysosome	lysosome	NOUN
bptjm-41	48	18	fusion	fusion	NOUN
bptjm-41	48	19	rather	rather	ADV
bptjm-41	48	20	than	than	ADP
bptjm-41	48	21	a	a	DET
bptjm-41	48	22	�	�	NOUN
bptjm-41	48	23	ecting	ecte	VERB
bptjm-41	48	24	the	the	DET
bptjm-41	48	25	acidity	acidity	NOUN
bptjm-41	48	26	and/or	and/or	CCONJ
bptjm-41	48	27	degradative	degradative	ADJ
bptjm-41	48	28	activities	activity	NOUN
bptjm-41	48	29	of	of	ADP
bptjm-41	48	30	lysosomes	lysosome	NOUN
bptjm-41	48	31	21	21	NUM
bptjm-41	48	32	.	.	PUNCT
bptjm-41	49	1	in	in	ADP
bptjm-41	49	2	addition	addition	NOUN
bptjm-41	49	3	,	,	PUNCT
bptjm-41	49	4	hcq	hcq	NOUN
bptjm-41	49	5	treatment	treatment	NOUN
bptjm-41	49	6	was	be	AUX
bptjm-41	49	7	associated	associate	VERB
bptjm-41	49	8	with	with	ADP
bptjm-41	49	9	"	"	PUNCT
bptjm-41	49	10	autophagy	autophagy	ADJ
bptjm-41	49	11	-	-	PUNCT
bptjm-41	49	12	independent	independent	ADJ
bptjm-41	49	13	"	"	PUNCT
bptjm-41	49	14	disorganization	disorganization	NOUN
bptjm-41	49	15	of	of	ADP
bptjm-41	49	16	the	the	DET
bptjm-41	49	17	golgi	golgi	NOUN
bptjm-41	49	18	and	and	CCONJ
bptjm-41	49	19	endo	endo	NOUN
bptjm-41	49	20	-	-	PUNCT
bptjm-41	49	21	lysosomal	lysosomal	ADJ
bptjm-41	49	22	systems	system	NOUN
bptjm-41	49	23	,	,	PUNCT
bptjm-41	49	24	with	with	ADP
bptjm-41	49	25	predominant	predominant	ADJ
bptjm-41	49	26	golgi	golgi	NOUN
bptjm-41	49	27	disorganization	disorganization	NOUN
bptjm-41	49	28	seen	see	VERB
bptjm-41	49	29	in	in	ADP
bptjm-41	49	30	kidney	kidney	NOUN
bptjm-41	49	31	and	and	CCONJ
bptjm-41	49	32	intestinal	intestinal	ADJ
bptjm-41	49	33	tissues	tissue	NOUN
bptjm-41	49	34	.	.	PUNCT
bptjm-41	50	1	the	the	DET
bptjm-41	50	2	microtubule	microtubule	NOUN
bptjm-41	50	3	-	-	PUNCT
bptjm-41	50	4	associated	associate	VERB
bptjm-41	50	5	protein	protein	NOUN
bptjm-41	50	6	i	i	PRON
bptjm-41	50	7	light	light	VERB
bptjm-41	50	8	chain	chain	NOUN
bptjm-41	50	9	(	(	PUNCT
bptjm-41	50	10	lc3	lc3	NOUN
bptjm-41	50	11	)	)	PUNCT
bptjm-41	50	12	family	family	NOUN
bptjm-41	50	13	of	of	ADP
bptjm-41	50	14	proteins	protein	NOUN
bptjm-41	50	15	(	(	PUNCT
bptjm-41	50	16	lc3a	lc3a	PROPN
bptjm-41	50	17	,	,	PUNCT
bptjm-41	50	18	b	b	NOUN
bptjm-41	50	19	,	,	PUNCT
bptjm-41	50	20	c	c	NOUN
bptjm-41	50	21	)	)	PUNCT
bptjm-41	50	22	22	22	NUM
bptjm-41	50	23	is	be	AUX
bptjm-41	50	24	the	the	DET
bptjm-41	50	25	major	major	ADJ
bptjm-41	50	26	structural	structural	ADJ
bptjm-41	50	27	protein	protein	NOUN
bptjm-41	50	28	family	family	NOUN
bptjm-41	50	29	of	of	ADP
bptjm-41	50	30	autophagosome	autophagosome	NOUN
bptjm-41	50	31	membranes	membrane	NOUN
bptjm-41	50	32	.	.	PUNCT
bptjm-41	51	1	lc3	lc3	NOUN
bptjm-41	51	2	-	-	PUNCT
bptjm-41	51	3	ii	ii	PROPN
bptjm-41	51	4	is	be	AUX
bptjm-41	51	5	generated	generate	VERB
bptjm-41	51	6	by	by	ADP
bptjm-41	51	7	the	the	DET
bptjm-41	51	8	conjugation	conjugation	NOUN
bptjm-41	51	9	of	of	ADP
bptjm-41	51	10	cytosolic	cytosolic	PROPN
bptjm-41	51	11	lc3	lc3	NOUN
bptjm-41	51	12	-	-	NOUN
bptjm-41	51	13	i	i	PRON
bptjm-41	51	14	to	to	PART
bptjm-41	51	15	phosphatidylethanolamine	phosphatidylethanolamine	VERB
bptjm-41	51	16	on	on	ADP
bptjm-41	51	17	the	the	DET
bptjm-41	51	18	surface	surface	NOUN
bptjm-41	51	19	of	of	ADP
bptjm-41	51	20	nascent	nascent	NOUN
bptjm-41	51	21	autophagosomes	autophagosome	NOUN
bptjm-41	51	22	.	.	PUNCT
bptjm-41	52	1	doeppner	doeppner	NOUN
bptjm-41	52	2	et	et	PROPN
bptjm-41	52	3	al	al	PROPN
bptjm-41	52	4	.	.	PROPN
bptjm-41	52	5	showed	show	VERB
bptjm-41	52	6	that	that	SCONJ
bptjm-41	52	7	the	the	DET
bptjm-41	52	8	cq	cq	ADV
bptjm-41	52	9	-	-	PUNCT
bptjm-41	52	10	treated	treat	VERB
bptjm-41	52	11	mice	mouse	NOUN
bptjm-41	52	12	exhibited	exhibit	VERB
bptjm-41	52	13	a	a	DET
bptjm-41	52	14	dose	dose	NOUN
bptjm-41	52	15	-	-	PUNCT
bptjm-41	52	16	dependent	dependent	ADJ
bptjm-41	52	17	increase	increase	NOUN
bptjm-41	52	18	in	in	ADP
bptjm-41	52	19	lc3b	lc3b	PROPN
bptjm-41	52	20	-	-	PUNCT
bptjm-41	52	21	ii	ii	NOUN
bptjm-41	52	22	as	as	ADV
bptjm-41	52	23	well	well	ADV
bptjm-41	52	24	as	as	ADP
bptjm-41	52	25	p62	p62	NOUN
bptjm-41	52	26	in	in	ADP
bptjm-41	52	27	the	the	DET
bptjm-41	52	28	liver	liver	NOUN
bptjm-41	52	29	and	and	CCONJ
bptjm-41	52	30	heart	heart	NOUN
bptjm-41	52	31	,	,	PUNCT
bptjm-41	52	32	as	as	SCONJ
bptjm-41	52	33	con	con	PROPN
bptjm-41	52	34	�	�	PROPN
bptjm-41	52	35	rmed	rme	VERB
bptjm-41	52	36	by	by	ADP
bptjm-41	52	37	transmission	transmission	NOUN
bptjm-41	52	38	electron	electron	NOUN
bptjm-41	52	39	microscopy	microscopy	NOUN
bptjm-41	52	40	17	17	NUM
bptjm-41	52	41	.	.	PUNCT
bptjm-41	53	1	curiously	curiously	ADV
bptjm-41	53	2	,	,	PUNCT
bptjm-41	53	3	the	the	DET
bptjm-41	53	4	treated	treat	VERB
bptjm-41	53	5	animals	animal	NOUN
bptjm-41	53	6	exhibited	exhibit	VERB
bptjm-41	53	7	increased	increase	VERB
bptjm-41	53	8	liver	liver	NOUN
bptjm-41	53	9	glycogen	glycogen	NOUN
bptjm-41	53	10	and	and	CCONJ
bptjm-41	53	11	reduced	reduce	VERB
bptjm-41	53	12	serum	serum	NOUN
bptjm-41	53	13	insulin	insulin	NOUN
bptjm-41	53	14	growth	growth	NOUN
bptjm-41	53	15	factor	factor	NOUN
bptjm-41	53	16	binding	bind	VERB
bptjm-41	53	17	protein	protein	NOUN
bptjm-41	53	18	3	3	NUM
bptjm-41	53	19	(	(	PUNCT
bptjm-41	53	20	igfbp3	igfbp3	NOUN
bptjm-41	53	21	)	)	PUNCT
bptjm-41	53	22	,	,	PUNCT
bptjm-41	53	23	though	though	SCONJ
bptjm-41	53	24	no	no	DET
bptjm-41	53	25	di	di	NOUN
bptjm-41	53	26	�	�	NOUN
bptjm-41	53	27	erence	erence	NOUN
bptjm-41	53	28	in	in	ADP
bptjm-41	53	29	igf-1	igf-1	NOUN
bptjm-41	53	30	,	,	PUNCT
bptjm-41	53	31	irs	irs	PROPN
bptjm-41	53	32	,	,	PUNCT
bptjm-41	53	33	or	or	CCONJ
bptjm-41	53	34	growth	growth	NOUN
bptjm-41	53	35	hormone	hormone	NOUN
bptjm-41	53	36	levels	level	NOUN
bptjm-41	53	37	23	23	NUM
bptjm-41	53	38	,	,	PUNCT
bptjm-41	53	39	24	24	NUM
bptjm-41	53	40	.	.	PUNCT
bptjm-41	54	1	cq	cq	NOUN
bptjm-41	54	2	treatment	treatment	NOUN
bptjm-41	54	3	elicited	elicit	VERB
bptjm-41	54	4	a	a	DET
bptjm-41	54	5	decrease	decrease	NOUN
bptjm-41	54	6	in	in	ADP
bptjm-41	54	7	glycogenolysis	glycogenolysis	NOUN
bptjm-41	54	8	in	in	ADP
bptjm-41	54	9	the	the	DET
bptjm-41	54	10	liver	liver	NOUN
bptjm-41	54	11	.	.	PUNCT
bptjm-41	55	1	berkeley	berkeley	PROPN
bptjm-41	55	2	pharma	pharma	PROPN
bptjm-41	55	3	tech	tech	PROPN
bptjm-41	55	4	journal	journal	NOUN
bptjm-41	55	5	of	of	ADP
bptjm-41	55	6	medicine	medicine	NOUN
bptjm-41	55	7	|	|	ADV
bptjm-41	55	8	4	4	NUM
bptjm-41	55	9	igfbp3	igfbp3	NOUN
bptjm-41	55	10	binds	bind	VERB
bptjm-41	55	11	igf1	igf1	PROPN
bptjm-41	55	12	and	and	CCONJ
bptjm-41	55	13	igf2	igf2	PROPN
bptjm-41	55	14	to	to	PART
bptjm-41	55	15	modulate	modulate	VERB
bptjm-41	55	16	their	their	PRON
bptjm-41	55	17	binding	binding	NOUN
bptjm-41	55	18	to	to	ADP
bptjm-41	55	19	the	the	DET
bptjm-41	55	20	igf-1	igf-1	NOUN
bptjm-41	55	21	receptor	receptor	NOUN
bptjm-41	55	22	.	.	PUNCT
bptjm-41	56	1	while	while	SCONJ
bptjm-41	56	2	igfbp3	igfbp3	NOUN
bptjm-41	56	3	levels	level	NOUN
bptjm-41	56	4	,	,	PUNCT
bptjm-41	56	5	like	like	ADP
bptjm-41	56	6	igfs	igfs	NOUN
bptjm-41	56	7	,	,	PUNCT
bptjm-41	56	8	are	be	AUX
bptjm-41	56	9	regulated	regulate	VERB
bptjm-41	56	10	by	by	ADP
bptjm-41	56	11	gh	gh	PROPN
bptjm-41	56	12	,	,	PUNCT
bptjm-41	56	13	expression	expression	NOUN
bptjm-41	56	14	in	in	ADP
bptjm-41	56	15	the	the	DET
bptjm-41	56	16	liver	liver	NOUN
bptjm-41	56	17	is	be	AUX
bptjm-41	56	18	gh	gh	PROPN
bptjm-41	56	19	-	-	PUNCT
bptjm-41	56	20	independent	independent	ADJ
bptjm-41	56	21	25	25	NUM
bptjm-41	56	22	.	.	PUNCT
bptjm-41	57	1	igfb3	igfb3	PROPN
bptjm-41	57	2	mediates	mediate	VERB
bptjm-41	57	3	a	a	DET
bptjm-41	57	4	plethora	plethora	NOUN
bptjm-41	57	5	of	of	ADP
bptjm-41	57	6	other	other	ADJ
bptjm-41	57	7	activities	activity	NOUN
bptjm-41	57	8	via	via	ADP
bptjm-41	57	9	its	its	PRON
bptjm-41	57	10	binding	binding	NOUN
bptjm-41	57	11	to	to	ADP
bptjm-41	57	12	a	a	DET
bptjm-41	57	13	number	number	NOUN
bptjm-41	57	14	of	of	ADP
bptjm-41	57	15	proteins	protein	NOUN
bptjm-41	57	16	and	and	CCONJ
bptjm-41	57	17	its	its	PRON
bptjm-41	57	18	interaction	interaction	NOUN
bptjm-41	57	19	with	with	ADP
bptjm-41	57	20	various	various	ADJ
bptjm-41	57	21	cell	cell	NOUN
bptjm-41	57	22	surface	surface	NOUN
bptjm-41	57	23	and	and	CCONJ
bptjm-41	57	24	nuclear	nuclear	ADJ
bptjm-41	57	25	signaling	signal	VERB
bptjm-41	57	26	pathways	pathway	NOUN
bptjm-41	57	27	.	.	PUNCT
bptjm-41	58	1	several	several	ADJ
bptjm-41	58	2	labs	lab	NOUN
bptjm-41	58	3	have	have	AUX
bptjm-41	58	4	demonstrated	demonstrate	VERB
bptjm-41	58	5	a	a	DET
bptjm-41	58	6	bene	bene	PROPN
bptjm-41	58	7	�	�	PROPN
bptjm-41	58	8	cial	cial	ADJ
bptjm-41	58	9	role	role	NOUN
bptjm-41	58	10	for	for	ADP
bptjm-41	58	11	reduced	reduced	ADJ
bptjm-41	58	12	igfb3	igfb3	NOUN
bptjm-41	58	13	in	in	ADP
bptjm-41	58	14	senescence	senescence	NOUN
bptjm-41	58	15	26	26	NUM
bptjm-41	58	16	,	,	PUNCT
bptjm-41	58	17	27	27	NUM
bptjm-41	58	18	,	,	PUNCT
bptjm-41	58	19	28	28	NUM
bptjm-41	58	20	.	.	PUNCT
bptjm-41	59	1	li	li	PROPN
bptjm-41	59	2	et	et	PROPN
bptjm-41	59	3	al	al	PROPN
bptjm-41	59	4	.	.	PROPN
bptjm-41	59	5	found	find	VERB
bptjm-41	59	6	that	that	SCONJ
bptjm-41	59	7	low	low	ADV
bptjm-41	59	8	-	-	PUNCT
bptjm-41	59	9	dose	dose	NOUN
bptjm-41	59	10	cq	cq	PROPN
bptjm-41	59	11	(	(	PUNCT
bptjm-41	59	12	0.1	0.1	NUM
bptjm-41	59	13	mg	mg	PROPN
bptjm-41	59	14	/	/	SYM
bptjm-41	59	15	kg	kg	PROPN
bptjm-41	59	16	given	give	VERB
bptjm-41	59	17	twice	twice	DET
bptjm-41	59	18	a	a	DET
bptjm-41	59	19	week	week	NOUN
bptjm-41	59	20	)	)	PUNCT
bptjm-41	59	21	extended	extend	VERB
bptjm-41	59	22	the	the	DET
bptjm-41	59	23	lifespan	lifespan	NOUN
bptjm-41	59	24	of	of	ADP
bptjm-41	59	25	aged	aged	ADJ
bptjm-41	59	26	rats	rat	NOUN
bptjm-41	59	27	when	when	SCONJ
bptjm-41	59	28	given	give	VERB
bptjm-41	59	29	in	in	ADP
bptjm-41	59	30	late	late	ADJ
bptjm-41	59	31	middle	middle	ADJ
bptjm-41	59	32	age	age	NOUN
bptjm-41	59	33	6	6	NUM
bptjm-41	59	34	.	.	PUNCT
bptjm-41	60	1	this	this	DET
bptjm-41	60	2	dose	dose	NOUN
bptjm-41	60	3	is	be	AUX
bptjm-41	60	4	~100	~100	NOUN
bptjm-41	60	5	-	-	PUNCT
bptjm-41	60	6	fold	fold	VERB
bptjm-41	60	7	lower	low	ADJ
bptjm-41	60	8	than	than	ADP
bptjm-41	60	9	doses	dose	NOUN
bptjm-41	60	10	typically	typically	ADV
bptjm-41	60	11	given	give	VERB
bptjm-41	60	12	as	as	ADP
bptjm-41	60	13	a	a	DET
bptjm-41	60	14	putative	putative	ADJ
bptjm-41	60	15	autophagy	autophagy	ADJ
bptjm-41	60	16	inhibitor	inhibitor	NOUN
bptjm-41	60	17	in	in	ADP
bptjm-41	60	18	cancer	cancer	NOUN
bptjm-41	60	19	29	29	NUM
bptjm-41	60	20	.	.	PUNCT
bptjm-41	61	1	qian	qian	PROPN
bptjm-41	61	2	et	et	PROPN
bptjm-41	61	3	al	al	PROPN
bptjm-41	61	4	.	.	PROPN
bptjm-41	61	5	attributed	attribute	VERB
bptjm-41	61	6	the	the	DET
bptjm-41	61	7	geroprotective	geroprotective	ADJ
bptjm-41	61	8	e	e	PROPN
bptjm-41	61	9	�	�	PROPN
bptjm-41	61	10	ect	ect	X
bptjm-41	61	11	of	of	ADP
bptjm-41	61	12	cq	cq	NOUN
bptjm-41	61	13	to	to	ADP
bptjm-41	61	14	atm	atm	NOUN
bptjm-41	61	15	activation	activation	NOUN
bptjm-41	61	16	leading	lead	VERB
bptjm-41	61	17	to	to	ADP
bptjm-41	61	18	enhanced	enhance	VERB
bptjm-41	61	19	dna	dna	PROPN
bptjm-41	61	20	damage	damage	NOUN
bptjm-41	61	21	repair	repair	NOUN
bptjm-41	61	22	within	within	ADP
bptjm-41	61	23	their	their	PRON
bptjm-41	61	24	c.	c.	NOUN
bptjm-41	61	25	elegans	elegan	NOUN
bptjm-41	61	26	and	and	CCONJ
bptjm-41	61	27	progeria	progeria	NOUN
bptjm-41	61	28	mouse	mouse	NOUN
bptjm-41	61	29	strain	strain	NOUN
bptjm-41	61	30	models	model	NOUN
bptjm-41	61	31	30	30	NUM
bptjm-41	61	32	.	.	PUNCT
bptjm-41	62	1	others	other	NOUN
bptjm-41	62	2	have	have	AUX
bptjm-41	62	3	shown	show	VERB
bptjm-41	62	4	that	that	DET
bptjm-41	62	5	activation	activation	NOUN
bptjm-41	62	6	of	of	ADP
bptjm-41	62	7	atm	atm	NOUN
bptjm-41	62	8	by	by	ADP
bptjm-41	62	9	cq	cq	PROPN
bptjm-41	62	10	can	can	AUX
bptjm-41	62	11	slow	slow	VERB
bptjm-41	62	12	atherosclerosis	atherosclerosis	NOUN
bptjm-41	62	13	,	,	PUNCT
bptjm-41	62	14	improve	improve	VERB
bptjm-41	62	15	insulin	insulin	NOUN
bptjm-41	62	16	sensitivity	sensitivity	NOUN
bptjm-41	62	17	,	,	PUNCT
bptjm-41	62	18	and	and	CCONJ
bptjm-41	62	19	rescue	rescue	NOUN
bptjm-41	62	20	glucose	glucose	NOUN
bptjm-41	62	21	intolerance	intolerance	NOUN
bptjm-41	62	22	in	in	ADP
bptjm-41	62	23	type	type	NOUN
bptjm-41	62	24	2	2	NUM
bptjm-41	62	25	diabetes	diabetes	NOUN
bptjm-41	62	26	(	(	PUNCT
bptjm-41	62	27	t2d	t2d	NOUN
bptjm-41	62	28	)	)	PUNCT
bptjm-41	62	29	31	31	NUM
bptjm-41	62	30	,	,	PUNCT
bptjm-41	62	31	32	32	NUM
bptjm-41	62	32	,	,	PUNCT
bptjm-41	62	33	33	33	NUM
bptjm-41	62	34	.	.	PUNCT
bptjm-41	63	1	li	li	PROPN
bptjm-41	63	2	et	et	PROPN
bptjm-41	63	3	al	al	PROPN
bptjm-41	63	4	.	.	PROPN
bptjm-41	63	5	studied	study	VERB
bptjm-41	63	6	the	the	DET
bptjm-41	63	7	transcriptomes	transcriptome	NOUN
bptjm-41	63	8	from	from	ADP
bptjm-41	63	9	cq	cq	ADV
bptjm-41	63	10	-	-	PUNCT
bptjm-41	63	11	treated	treat	VERB
bptjm-41	63	12	and	and	CCONJ
bptjm-41	63	13	control	control	VERB
bptjm-41	63	14	old	old	ADJ
bptjm-41	63	15	rats	rat	NOUN
bptjm-41	63	16	to	to	ADP
bptjm-41	63	17	de	de	PROPN
bptjm-41	63	18	�	�	PROPN
bptjm-41	63	19	ne	ne	NOUN
bptjm-41	63	20	cq	cq	PROPN
bptjm-41	63	21	-	-	PUNCT
bptjm-41	63	22	induced	induced	ADJ
bptjm-41	63	23	,	,	PUNCT
bptjm-41	63	24	di	di	NOUN
bptjm-41	63	25	�	�	PROPN
bptjm-41	63	26	erentially	erentially	ADV
bptjm-41	63	27	expressed	express	VERB
bptjm-41	63	28	genes	gene	NOUN
bptjm-41	63	29	so	so	ADV
bptjm-41	63	30	-	-	PUNCT
bptjm-41	63	31	called	call	VERB
bptjm-41	63	32	“	"	PUNCT
bptjm-41	63	33	cq	cq	NUM
bptjm-41	63	34	degs	deg	NOUN
bptjm-41	63	35	”	"	PUNCT
bptjm-41	63	36	across	across	ADP
bptjm-41	63	37	multiple	multiple	ADJ
bptjm-41	63	38	tissues	tissue	NOUN
bptjm-41	63	39	.	.	PUNCT
bptjm-41	64	1	for	for	ADP
bptjm-41	64	2	example	example	NOUN
bptjm-41	64	3	,	,	PUNCT
bptjm-41	64	4	40	40	NUM
bptjm-41	64	5	%	%	NOUN
bptjm-41	64	6	of	of	ADP
bptjm-41	64	7	kidney	kidney	NOUN
bptjm-41	64	8	-	-	PUNCT
bptjm-41	64	9	speci	speci	NOUN
bptjm-41	64	10	�	�	PROPN
bptjm-41	64	11	c	c	NOUN
bptjm-41	64	12	aged	aged	ADJ
bptjm-41	64	13	genes	gene	NOUN
bptjm-41	64	14	,	,	PUNCT
bptjm-41	64	15	30	30	NUM
bptjm-41	64	16	%	%	NOUN
bptjm-41	64	17	of	of	ADP
bptjm-41	64	18	small	small	ADJ
bptjm-41	64	19	intestine	intestine	NOUN
bptjm-41	64	20	-	-	PUNCT
bptjm-41	64	21	speci	speci	NOUN
bptjm-41	64	22	�	�	PROPN
bptjm-41	64	23	c	c	NOUN
bptjm-41	64	24	aged	aged	ADJ
bptjm-41	64	25	genes	gene	NOUN
bptjm-41	64	26	,	,	PUNCT
bptjm-41	64	27	and	and	CCONJ
bptjm-41	64	28	20	20	NUM
bptjm-41	64	29	%	%	NOUN
bptjm-41	64	30	of	of	ADP
bptjm-41	64	31	liver	liver	NOUN
bptjm-41	64	32	-	-	PUNCT
bptjm-41	64	33	speci	speci	NOUN
bptjm-41	64	34	�	�	PROPN
bptjm-41	64	35	c	c	NOUN
bptjm-41	64	36	aged	aged	ADJ
bptjm-41	64	37	genes	gene	NOUN
bptjm-41	64	38	were	be	AUX
bptjm-41	64	39	"	"	PUNCT
bptjm-41	64	40	rescued	rescue	VERB
bptjm-41	64	41	"	"	PUNCT
bptjm-41	64	42	by	by	ADP
bptjm-41	64	43	cq	cq	PROPN
bptjm-41	64	44	treatment	treatment	NOUN
bptjm-41	64	45	.	.	PUNCT
bptjm-41	65	1	these	these	DET
bptjm-41	65	2	changes	change	NOUN
bptjm-41	65	3	were	be	AUX
bptjm-41	65	4	consistent	consistent	ADJ
bptjm-41	65	5	with	with	ADP
bptjm-41	65	6	the	the	DET
bptjm-41	65	7	reduced	reduce	VERB
bptjm-41	65	8	�	�	NOUN
bptjm-41	65	9	brosis	brosis	NOUN
bptjm-41	65	10	and	and	CCONJ
bptjm-41	65	11	improved	improved	ADJ
bptjm-41	65	12	histology	histology	NOUN
bptjm-41	65	13	of	of	ADP
bptjm-41	65	14	the	the	DET
bptjm-41	65	15	kidneys	kidney	NOUN
bptjm-41	65	16	compared	compare	VERB
bptjm-41	65	17	to	to	ADP
bptjm-41	65	18	other	other	ADJ
bptjm-41	65	19	tissues	tissue	NOUN
bptjm-41	65	20	.	.	PUNCT
bptjm-41	66	1	contrary	contrary	ADJ
bptjm-41	66	2	to	to	ADP
bptjm-41	66	3	expectation	expectation	NOUN
bptjm-41	66	4	,	,	PUNCT
bptjm-41	66	5	cq	cq	NUM
bptjm-41	66	6	treatment	treatment	NOUN
bptjm-41	66	7	augmented	augment	VERB
bptjm-41	66	8	a	a	DET
bptjm-41	66	9	number	number	NOUN
bptjm-41	66	10	of	of	ADP
bptjm-41	66	11	genes	gene	NOUN
bptjm-41	66	12	associated	associate	VERB
bptjm-41	66	13	with	with	ADP
bptjm-41	66	14	various	various	ADJ
bptjm-41	66	15	cardiac	cardiac	ADJ
bptjm-41	66	16	diseases	disease	NOUN
bptjm-41	66	17	(	(	PUNCT
bptjm-41	66	18	e.g.	e.g.	ADV
bptjm-41	66	19	heart	heart	NOUN
bptjm-41	66	20	failure	failure	NOUN
bptjm-41	66	21	,	,	PUNCT
bptjm-41	66	22	cardiac	cardiac	ADJ
bptjm-41	66	23	arrhythmias	arrhythmia	NOUN
bptjm-41	66	24	,	,	PUNCT
bptjm-41	66	25	ischemic	ischemic	ADJ
bptjm-41	66	26	cardiomyopathy	cardiomyopathy	ADJ
bptjm-41	66	27	(	(	PUNCT
bptjm-41	66	28	caps2	caps2	NOUN
bptjm-41	66	29	)	)	PUNCT
bptjm-41	66	30	,	,	PUNCT
bptjm-41	66	31	hypertrophic	hypertrophic	ADJ
bptjm-41	66	32	cardiomyopathy	cardiomyopathy	ADJ
bptjm-41	66	33	,	,	PUNCT
bptjm-41	66	34	and	and	CCONJ
bptjm-41	66	35	cardiac	cardiac	ADJ
bptjm-41	66	36	arrhythmias	arrhythmia	NOUN
bptjm-41	66	37	(	(	PUNCT
bptjm-41	66	38	myh7	myh7	PROPN
bptjm-41	66	39	)	)	PUNCT
bptjm-41	66	40	.	.	PUNCT
bptjm-41	67	1	thus	thus	ADV
bptjm-41	67	2	,	,	PUNCT
bptjm-41	67	3	cq	cq	PRON
bptjm-41	67	4	treatment	treatment	NOUN
bptjm-41	67	5	may	may	AUX
bptjm-41	67	6	actually	actually	ADV
bptjm-41	67	7	mediate	mediate	VERB
bptjm-41	67	8	pro	pro	ADJ
bptjm-41	67	9	-	-	ADJ
bptjm-41	67	10	aging	aging	ADJ
bptjm-41	67	11	activity	activity	NOUN
bptjm-41	67	12	in	in	ADP
bptjm-41	67	13	certain	certain	ADJ
bptjm-41	67	14	tissues	tissue	NOUN
bptjm-41	67	15	6	6	NUM
bptjm-41	67	16	.	.	PUNCT
bptjm-41	68	1	summary	summary	VERB
bptjm-41	68	2	a	a	DET
bptjm-41	68	3	number	number	NOUN
bptjm-41	68	4	of	of	ADP
bptjm-41	68	5	labs	lab	NOUN
bptjm-41	68	6	have	have	AUX
bptjm-41	68	7	studied	study	VERB
bptjm-41	68	8	several	several	ADJ
bptjm-41	68	9	animal	animal	NOUN
bptjm-41	68	10	species	specie	NOUN
bptjm-41	68	11	to	to	PART
bptjm-41	68	12	generate	generate	VERB
bptjm-41	68	13	data	datum	NOUN
bptjm-41	68	14	suggesting	suggest	VERB
bptjm-41	68	15	that	that	SCONJ
bptjm-41	68	16	cq	cq	PROPN
bptjm-41	68	17	can	can	AUX
bptjm-41	68	18	mediate	mediate	VERB
bptjm-41	68	19	a	a	DET
bptjm-41	68	20	pro	pro	ADJ
bptjm-41	68	21	-	-	NOUN
bptjm-41	68	22	longevity	longevity	ADJ
bptjm-41	68	23	e	e	NOUN
bptjm-41	68	24	�	�	PROPN
bptjm-41	68	25	ect	ect	ADJ
bptjm-41	68	26	.	.	PUNCT
bptjm-41	69	1	mechanistic	mechanistic	ADJ
bptjm-41	69	2	studies	study	NOUN
bptjm-41	69	3	indicate	indicate	VERB
bptjm-41	69	4	that	that	SCONJ
bptjm-41	69	5	multiple	multiple	ADJ
bptjm-41	69	6	mechanisms	mechanism	NOUN
bptjm-41	69	7	are	be	AUX
bptjm-41	69	8	at	at	ADP
bptjm-41	69	9	play	play	NOUN
bptjm-41	69	10	,	,	PUNCT
bptjm-41	69	11	each	each	PRON
bptjm-41	69	12	addressing	address	VERB
bptjm-41	69	13	a	a	DET
bptjm-41	69	14	hallmark	hallmark	NOUN
bptjm-41	69	15	of	of	ADP
bptjm-41	69	16	aging	age	VERB
bptjm-41	69	17	34	34	NUM
bptjm-41	69	18	.	.	PUNCT
bptjm-41	70	1	while	while	SCONJ
bptjm-41	70	2	cq	cq	PROPN
bptjm-41	70	3	and	and	CCONJ
bptjm-41	70	4	hcq	hcq	NOUN
bptjm-41	70	5	are	be	AUX
bptjm-41	70	6	familiar	familiar	ADJ
bptjm-41	70	7	to	to	ADP
bptjm-41	70	8	cell	cell	NOUN
bptjm-41	70	9	biologists	biologist	NOUN
bptjm-41	70	10	as	as	ADP
bptjm-41	70	11	prototypic	prototypic	ADJ
bptjm-41	70	12	berkeley	berkeley	PROPN
bptjm-41	70	13	pharma	pharma	PROPN
bptjm-41	70	14	tech	tech	NOUN
bptjm-41	70	15	journal	journal	NOUN
bptjm-41	70	16	of	of	ADP
bptjm-41	70	17	medicine	medicine	NOUN
bptjm-41	70	18	|	|	ADV
bptjm-41	70	19	5	5	NUM
bptjm-41	70	20	lysosomotropic	lysosomotropic	ADJ
bptjm-41	70	21	e	e	NOUN
bptjm-41	70	22	�	�	NOUN
bptjm-41	70	23	ect	ect	ADJ
bptjm-41	70	24	tool	tool	NOUN
bptjm-41	70	25	compounds	compound	NOUN
bptjm-41	70	26	,	,	PUNCT
bptjm-41	70	27	numerous	numerous	ADJ
bptjm-41	70	28	diverse	diverse	ADJ
bptjm-41	70	29	studies	study	NOUN
bptjm-41	70	30	highlight	highlight	VERB
bptjm-41	70	31	the	the	DET
bptjm-41	70	32	plethora	plethora	NOUN
bptjm-41	70	33	of	of	ADP
bptjm-41	70	34	other	other	ADJ
bptjm-41	70	35	activities	activity	NOUN
bptjm-41	70	36	mediated	mediate	VERB
bptjm-41	70	37	by	by	ADP
bptjm-41	70	38	cq	cq	PROPN
bptjm-41	70	39	.	.	PROPN
bptjm-41	70	40	isolated	isolated	ADJ
bptjm-41	70	41	papers	paper	NOUN
bptjm-41	70	42	over	over	ADP
bptjm-41	70	43	the	the	DET
bptjm-41	70	44	past	past	ADJ
bptjm-41	70	45	20	20	NUM
bptjm-41	70	46	years	year	NOUN
bptjm-41	70	47	have	have	VERB
bptjm-41	70	48	identi	identi	ADJ
bptjm-41	70	49	�	�	PROPN
bptjm-41	70	50	ed	ed	ADJ
bptjm-41	70	51	non	non	ADJ
bptjm-41	70	52	-	-	ADJ
bptjm-41	70	53	autophagy	autophagy	ADJ
bptjm-41	70	54	-	-	PUNCT
bptjm-41	70	55	mediated	mediate	VERB
bptjm-41	70	56	e	e	NOUN
bptjm-41	70	57	�	�	NOUN
bptjm-41	70	58	ects	ect	NOUN
bptjm-41	70	59	of	of	ADP
bptjm-41	70	60	cq	cq	NOUN
bptjm-41	70	61	.	.	PUNCT
bptjm-41	71	1	for	for	ADP
bptjm-41	71	2	example	example	NOUN
bptjm-41	71	3	,	,	PUNCT
bptjm-41	71	4	cq	cq	PROPN
bptjm-41	71	5	improves	improve	VERB
bptjm-41	71	6	vasculogenesis	vasculogenesis	NOUN
bptjm-41	71	7	35	35	NUM
bptjm-41	71	8	,	,	PUNCT
bptjm-41	71	9	insulin	insulin	NOUN
bptjm-41	71	10	metabolism	metabolism	NOUN
bptjm-41	71	11	31	31	NUM
bptjm-41	71	12	,	,	PUNCT
bptjm-41	71	13	�	�	PROPN
bptjm-41	71	14	brosis	brosis	NOUN
bptjm-41	71	15	36	36	NUM
bptjm-41	71	16	,	,	PUNCT
bptjm-41	71	17	reduces	reduce	VERB
bptjm-41	71	18	oxidative	oxidative	ADJ
bptjm-41	71	19	stress	stress	NOUN
bptjm-41	71	20	37	37	NUM
bptjm-41	71	21	,	,	PUNCT
bptjm-41	71	22	modulates	modulate	NOUN
bptjm-41	71	23	autophagic	autophagic	PROPN
bptjm-41	71	24	�	�	PROPN
bptjm-41	71	25	ux	ux	PROPN
bptjm-41	71	26	21	21	NUM
bptjm-41	71	27	,	,	PUNCT
bptjm-41	71	28	boosts	boost	VERB
bptjm-41	71	29	dna	dna	PROPN
bptjm-41	71	30	repair	repair	NOUN
bptjm-41	71	31	via	via	ADP
bptjm-41	71	32	stm	stm	PROPN
bptjm-41	71	33	30	30	NUM
bptjm-41	71	34	,	,	PUNCT
bptjm-41	71	35	and	and	CCONJ
bptjm-41	71	36	attenuates	attenuate	NOUN
bptjm-41	71	37	atherogenesis	atherogenesis	VERB
bptjm-41	71	38	33	33	NUM
bptjm-41	71	39	to	to	PART
bptjm-41	71	40	name	name	VERB
bptjm-41	71	41	a	a	DET
bptjm-41	71	42	few	few	ADJ
bptjm-41	71	43	.	.	PUNCT
bptjm-41	72	1	when	when	SCONJ
bptjm-41	72	2	we	we	PRON
bptjm-41	72	3	began	begin	VERB
bptjm-41	72	4	looking	look	VERB
bptjm-41	72	5	into	into	ADP
bptjm-41	72	6	this	this	DET
bptjm-41	72	7	story	story	NOUN
bptjm-41	72	8	,	,	PUNCT
bptjm-41	72	9	we	we	PRON
bptjm-41	72	10	sought	seek	VERB
bptjm-41	72	11	a	a	DET
bptjm-41	72	12	unifying	unifying	ADJ
bptjm-41	72	13	mechanism	mechanism	NOUN
bptjm-41	72	14	,	,	PUNCT
bptjm-41	72	15	pathway	pathway	NOUN
bptjm-41	72	16	,	,	PUNCT
bptjm-41	72	17	target	target	NOUN
bptjm-41	72	18	,	,	PUNCT
bptjm-41	72	19	etc	etc	X
bptjm-41	72	20	.	.	X
bptjm-41	72	21	to	to	PART
bptjm-41	72	22	explain	explain	VERB
bptjm-41	72	23	the	the	DET
bptjm-41	72	24	increased	increase	VERB
bptjm-41	72	25	lifespans	lifespan	NOUN
bptjm-41	72	26	.	.	PUNCT
bptjm-41	73	1	unfortunately	unfortunately	ADV
bptjm-41	73	2	,	,	PUNCT
bptjm-41	73	3	at	at	ADP
bptjm-41	73	4	the	the	DET
bptjm-41	73	5	present	present	ADJ
bptjm-41	73	6	time	time	NOUN
bptjm-41	73	7	,	,	PUNCT
bptjm-41	73	8	descriptive	descriptive	ADJ
bptjm-41	73	9	studies	study	NOUN
bptjm-41	73	10	nominate	nominate	VERB
bptjm-41	73	11	many	many	ADJ
bptjm-41	73	12	parallel	parallel	ADJ
bptjm-41	73	13	mechanisms	mechanism	NOUN
bptjm-41	73	14	.	.	PUNCT
bptjm-41	74	1	the	the	DET
bptjm-41	74	2	detailed	detailed	ADJ
bptjm-41	74	3	transcriptome	transcriptome	ADJ
bptjm-41	74	4	studies	study	NOUN
bptjm-41	74	5	of	of	ADP
bptjm-41	74	6	li	li	PROPN
bptjm-41	74	7	et	et	PROPN
bptjm-41	74	8	al	al	PROPN
bptjm-41	74	9	.	.	PROPN
bptjm-41	74	10	show	show	VERB
bptjm-41	74	11	quite	quite	ADV
bptjm-41	74	12	variable	variable	ADJ
bptjm-41	74	13	tissue	tissue	NOUN
bptjm-41	74	14	speci	speci	NOUN
bptjm-41	74	15	�	�	PROPN
bptjm-41	74	16	c	c	PROPN
bptjm-41	74	17	patterns	pattern	NOUN
bptjm-41	74	18	,	,	PUNCT
bptjm-41	74	19	with	with	ADP
bptjm-41	74	20	some	some	PRON
bptjm-41	74	21	that	that	PRON
bptjm-41	74	22	are	be	AUX
bptjm-41	74	23	bene	bene	PROPN
bptjm-41	74	24	�	�	PROPN
bptjm-41	74	25	cial	cial	NOUN
bptjm-41	74	26	for	for	ADP
bptjm-41	74	27	health	health	NOUN
bptjm-41	74	28	span	span	NOUN
bptjm-41	74	29	and	and	CCONJ
bptjm-41	74	30	others	other	NOUN
bptjm-41	74	31	that	that	PRON
bptjm-41	74	32	are	be	AUX
bptjm-41	74	33	consistent	consistent	ADJ
bptjm-41	74	34	with	with	ADP
bptjm-41	74	35	cardiac	cardiac	ADJ
bptjm-41	74	36	diseases	disease	NOUN
bptjm-41	74	37	6	6	NUM
bptjm-41	74	38	.	.	PUNCT
bptjm-41	75	1	of	of	ADP
bptjm-41	75	2	course	course	ADV
bptjm-41	75	3	,	,	PUNCT
bptjm-41	75	4	investigating	investigate	VERB
bptjm-41	75	5	the	the	DET
bptjm-41	75	6	geroprotective	geroprotective	ADJ
bptjm-41	75	7	e	e	NOUN
bptjm-41	75	8	�	�	PROPN
bptjm-41	75	9	ects	ect	NOUN
bptjm-41	75	10	of	of	ADP
bptjm-41	75	11	cq	cq	NOUN
bptjm-41	75	12	using	use	VERB
bptjm-41	75	13	horvath	horvath	PROPN
bptjm-41	75	14	or	or	CCONJ
bptjm-41	75	15	other	other	ADJ
bptjm-41	75	16	methylation	methylation	NOUN
bptjm-41	75	17	clocks	clock	NOUN
bptjm-41	75	18	might	might	AUX
bptjm-41	75	19	lead	lead	VERB
bptjm-41	75	20	to	to	ADP
bptjm-41	75	21	interesting	interesting	ADJ
bptjm-41	75	22	�	�	NOUN
bptjm-41	75	23	ndings	nding	NOUN
bptjm-41	75	24	.	.	PUNCT
bptjm-41	76	1	medical	medical	ADJ
bptjm-41	76	2	implications	implication	NOUN
bptjm-41	76	3	as	as	SCONJ
bptjm-41	76	4	noted	note	VERB
bptjm-41	76	5	above	above	ADV
bptjm-41	76	6	,	,	PUNCT
bptjm-41	76	7	cq	cq	PROPN
bptjm-41	76	8	and	and	CCONJ
bptjm-41	76	9	hcq	hcq	NOUN
bptjm-41	76	10	are	be	AUX
bptjm-41	76	11	widely	widely	ADV
bptjm-41	76	12	used	use	VERB
bptjm-41	76	13	drugs	drug	NOUN
bptjm-41	76	14	38	38	NUM
bptjm-41	76	15	.	.	PUNCT
bptjm-41	77	1	the	the	DET
bptjm-41	77	2	studies	study	NOUN
bptjm-41	77	3	of	of	ADP
bptjm-41	77	4	li	li	PROPN
bptjm-41	77	5	et	et	PROPN
bptjm-41	77	6	al	al	PROPN
bptjm-41	77	7	.	.	PROPN
bptjm-41	77	8	and	and	CCONJ
bptjm-41	77	9	doeppner	doeppner	NOUN
bptjm-41	77	10	et	et	PROPN
bptjm-41	77	11	al	al	PROPN
bptjm-41	77	12	.	.	PUNCT
bptjm-41	77	13	support	support	NOUN
bptjm-41	77	14	further	far	ADV
bptjm-41	77	15	,	,	PUNCT
bptjm-41	77	16	possibly	possibly	ADV
bptjm-41	77	17	human	human	ADJ
bptjm-41	77	18	studies	study	NOUN
bptjm-41	77	19	of	of	ADP
bptjm-41	77	20	these	these	DET
bptjm-41	77	21	drugs	drug	NOUN
bptjm-41	77	22	.	.	PUNCT
bptjm-41	78	1	on	on	ADP
bptjm-41	78	2	october	october	PROPN
bptjm-41	78	3	8–13	8–13	NOUN
bptjm-41	78	4	,	,	PUNCT
bptjm-41	78	5	2013	2013	NUM
bptjm-41	78	6	,	,	PUNCT
bptjm-41	78	7	a	a	DET
bptjm-41	78	8	workshop	workshop	NOUN
bptjm-41	78	9	entitled	entitle	VERB
bptjm-41	78	10	‘	'	PUNCT
bptjm-41	78	11	interventions	intervention	NOUN
bptjm-41	78	12	to	to	PART
bptjm-41	78	13	slow	slow	VERB
bptjm-41	78	14	aging	aging	NOUN
bptjm-41	78	15	in	in	ADP
bptjm-41	78	16	humans	human	NOUN
bptjm-41	78	17	:	:	PUNCT
bptjm-41	78	18	are	be	AUX
bptjm-41	78	19	we	we	PRON
bptjm-41	78	20	ready	ready	ADJ
bptjm-41	78	21	?	?	PUNCT
bptjm-41	78	22	’	'	PUNCT
bptjm-41	78	23	was	be	AUX
bptjm-41	78	24	held	hold	VERB
bptjm-41	78	25	in	in	ADP
bptjm-41	78	26	erice	erice	NOUN
bptjm-41	78	27	,	,	PUNCT
bptjm-41	78	28	italy	italy	PROPN
bptjm-41	78	29	39	39	NUM
bptjm-41	78	30	.	.	PUNCT
bptjm-41	79	1	at	at	ADP
bptjm-41	79	2	the	the	DET
bptjm-41	79	3	time	time	NOUN
bptjm-41	79	4	,	,	PUNCT
bptjm-41	79	5	a	a	DET
bptjm-41	79	6	number	number	NOUN
bptjm-41	79	7	of	of	ADP
bptjm-41	79	8	interventions	intervention	NOUN
bptjm-41	79	9	were	be	AUX
bptjm-41	79	10	deemed	deem	VERB
bptjm-41	79	11	worthy	worthy	ADJ
bptjm-41	79	12	of	of	ADP
bptjm-41	79	13	human	human	ADJ
bptjm-41	79	14	clinical	clinical	ADJ
bptjm-41	79	15	trials	trial	NOUN
bptjm-41	79	16	.	.	PUNCT
bptjm-41	80	1	since	since	SCONJ
bptjm-41	80	2	then	then	ADV
bptjm-41	80	3	,	,	PUNCT
bptjm-41	80	4	some	some	PRON
bptjm-41	80	5	of	of	ADP
bptjm-41	80	6	these	these	DET
bptjm-41	80	7	ideas	idea	NOUN
bptjm-41	80	8	have	have	AUX
bptjm-41	80	9	been	be	AUX
bptjm-41	80	10	put	put	VERB
bptjm-41	80	11	to	to	ADP
bptjm-41	80	12	the	the	DET
bptjm-41	80	13	test	test	NOUN
bptjm-41	80	14	or	or	CCONJ
bptjm-41	80	15	are	be	AUX
bptjm-41	80	16	being	be	AUX
bptjm-41	80	17	tested	test	VERB
bptjm-41	80	18	.	.	PUNCT
bptjm-41	81	1	with	with	ADP
bptjm-41	81	2	regard	regard	NOUN
bptjm-41	81	3	to	to	ADP
bptjm-41	81	4	development	development	NOUN
bptjm-41	81	5	of	of	ADP
bptjm-41	81	6	cq	cq	PROPN
bptjm-41	81	7	/	/	SYM
bptjm-41	81	8	hcq	hcq	PROPN
bptjm-41	81	9	,	,	PUNCT
bptjm-41	81	10	suitable	suitable	ADJ
bptjm-41	81	11	biomarkers	biomarker	NOUN
bptjm-41	81	12	will	will	AUX
bptjm-41	81	13	need	need	VERB
bptjm-41	81	14	to	to	PART
bptjm-41	81	15	be	be	AUX
bptjm-41	81	16	validated	validate	VERB
bptjm-41	81	17	.	.	PUNCT
bptjm-41	82	1	at	at	ADP
bptjm-41	82	2	low	low	ADJ
bptjm-41	82	3	doses	dose	NOUN
bptjm-41	82	4	,	,	PUNCT
bptjm-41	82	5	cq	cq	NOUN
bptjm-41	82	6	or	or	CCONJ
bptjm-41	82	7	hcq	hcq	NOUN
bptjm-41	82	8	seem	seem	VERB
bptjm-41	82	9	to	to	PART
bptjm-41	82	10	qualify	qualify	VERB
bptjm-41	82	11	for	for	ADP
bptjm-41	82	12	evaluation	evaluation	NOUN
bptjm-41	82	13	in	in	ADP
bptjm-41	82	14	humans	human	NOUN
bptjm-41	82	15	.	.	PUNCT
bptjm-41	83	1	however	however	ADV
bptjm-41	83	2	,	,	PUNCT
bptjm-41	83	3	the	the	DET
bptjm-41	83	4	safety	safety	NOUN
bptjm-41	83	5	pro	pro	X
bptjm-41	83	6	�	�	VERB
bptjm-41	83	7	le	le	X
bptjm-41	83	8	of	of	ADP
bptjm-41	83	9	this	this	DET
bptjm-41	83	10	class	class	NOUN
bptjm-41	83	11	of	of	ADP
bptjm-41	83	12	drugs	drug	NOUN
bptjm-41	83	13	will	will	AUX
bptjm-41	83	14	need	need	VERB
bptjm-41	83	15	to	to	PART
bptjm-41	83	16	be	be	AUX
bptjm-41	83	17	considered	consider	VERB
bptjm-41	83	18	.	.	PUNCT
bptjm-41	84	1	for	for	ADP
bptjm-41	84	2	instance	instance	NOUN
bptjm-41	84	3	,	,	PUNCT
bptjm-41	84	4	periodic	periodic	ADJ
bptjm-41	84	5	eye	eye	NOUN
bptjm-41	84	6	exams	exam	NOUN
bptjm-41	84	7	and	and	CCONJ
bptjm-41	84	8	cardiac	cardiac	ADJ
bptjm-41	84	9	monitoring	monitoring	NOUN
bptjm-41	84	10	are	be	AUX
bptjm-41	84	11	routine	routine	ADJ
bptjm-41	84	12	40	40	NUM
bptjm-41	84	13	at	at	ADP
bptjm-41	84	14	doses	dose	NOUN
bptjm-41	84	15	commonly	commonly	ADV
bptjm-41	84	16	used	use	VERB
bptjm-41	84	17	in	in	ADP
bptjm-41	84	18	rheumatology	rheumatology	NOUN
bptjm-41	84	19	38	38	NUM
bptjm-41	84	20	.	.	PUNCT
bptjm-41	85	1	clearly	clearly	ADV
bptjm-41	85	2	these	these	DET
bptjm-41	85	3	anti	anti	NOUN
bptjm-41	85	4	-	-	NOUN
bptjm-41	85	5	malarials	malarial	NOUN
bptjm-41	85	6	have	have	AUX
bptjm-41	85	7	come	come	VERB
bptjm-41	85	8	a	a	DET
bptjm-41	85	9	long	long	ADJ
bptjm-41	85	10	way	way	NOUN
bptjm-41	85	11	from	from	ADP
bptjm-41	85	12	the	the	DET
bptjm-41	85	13	rainforests	rainforest	NOUN
bptjm-41	85	14	of	of	ADP
bptjm-41	85	15	south	south	PROPN
bptjm-41	85	16	america	america	PROPN
bptjm-41	85	17	!	!	PUNCT
bptjm-41	86	1	berkeley	berkeley	PROPN
bptjm-41	86	2	pharma	pharma	PROPN
bptjm-41	86	3	tech	tech	PROPN
bptjm-41	86	4	journal	journal	NOUN
bptjm-41	86	5	of	of	ADP
bptjm-41	86	6	medicine	medicine	NOUN
bptjm-41	86	7	|	|	ADV
bptjm-41	86	8	6	6	NUM
bptjm-41	86	9	references	reference	NOUN
bptjm-41	86	10	1	1	NUM
bptjm-41	86	11	.	.	PUNCT
bptjm-41	87	1	plantone	plantone	PROPN
bptjm-41	87	2	d	d	PROPN
bptjm-41	87	3	,	,	PUNCT
bptjm-41	87	4	koudriavtseva	koudriavtseva	PROPN
bptjm-41	87	5	t.	t.	PROPN
bptjm-41	87	6	current	current	ADJ
bptjm-41	87	7	and	and	CCONJ
bptjm-41	87	8	future	future	ADJ
bptjm-41	87	9	use	use	NOUN
bptjm-41	87	10	of	of	ADP
bptjm-41	87	11	chloroquine	chloroquine	NOUN
bptjm-41	87	12	and	and	CCONJ
bptjm-41	87	13	hydroxychloroquine	hydroxychloroquine	NOUN
bptjm-41	87	14	in	in	ADP
bptjm-41	87	15	infectious	infectious	ADJ
bptjm-41	87	16	,	,	PUNCT
bptjm-41	87	17	immune	immune	ADJ
bptjm-41	87	18	,	,	PUNCT
bptjm-41	87	19	neoplastic	neoplastic	ADJ
bptjm-41	87	20	,	,	PUNCT
bptjm-41	87	21	and	and	CCONJ
bptjm-41	87	22	neurological	neurological	ADJ
bptjm-41	87	23	diseases	disease	NOUN
bptjm-41	87	24	:	:	PUNCT
bptjm-41	87	25	a	a	DET
bptjm-41	87	26	mini	mini	NOUN
bptjm-41	87	27	-	-	NOUN
bptjm-41	87	28	review	review	NOUN
bptjm-41	87	29	.	.	PUNCT
bptjm-41	88	1	clinical	clinical	ADJ
bptjm-41	88	2	drug	drug	NOUN
bptjm-41	88	3	investigation	investigation	NOUN
bptjm-41	88	4	.	.	PUNCT
bptjm-41	89	1	2018;38(8):653	2018;38(8):653	NUM
bptjm-41	89	2	-	-	SYM
bptjm-41	89	3	671	671	NUM
bptjm-41	89	4	.	.	PUNCT
bptjm-41	90	1	doi:10.1007	doi:10.1007	VERB
bptjm-41	90	2	/	/	SYM
bptjm-41	90	3	s40261	s40261	PROPN
bptjm-41	90	4	-	-	PUNCT
bptjm-41	90	5	018	018	NUM
bptjm-41	90	6	-	-	PUNCT
bptjm-41	90	7	0656	0656	NUM
bptjm-41	90	8	-	-	PUNCT
bptjm-41	90	9	y	y	PROPN
bptjm-41	90	10	2	2	NUM
bptjm-41	90	11	.	.	PUNCT
bptjm-41	91	1	rasmussen	rasmussen	PROPN
bptjm-41	91	2	c	c	PROPN
bptjm-41	91	3	,	,	PUNCT
bptjm-41	91	4	alonso	alonso	PROPN
bptjm-41	91	5	p	p	X
bptjm-41	91	6	,	,	PUNCT
bptjm-41	91	7	ringwald	ringwald	PROPN
bptjm-41	91	8	p.	p.	PROPN
bptjm-41	91	9	current	current	PROPN
bptjm-41	91	10	and	and	CCONJ
bptjm-41	91	11	emerging	emerge	VERB
bptjm-41	91	12	strategies	strategy	NOUN
bptjm-41	91	13	to	to	PART
bptjm-41	91	14	combat	combat	VERB
bptjm-41	91	15	antimalarial	antimalarial	ADJ
bptjm-41	91	16	resistance	resistance	NOUN
bptjm-41	91	17	.	.	PUNCT
bptjm-41	92	1	expert	expert	NOUN
bptjm-41	92	2	review	review	NOUN
bptjm-41	92	3	of	of	ADP
bptjm-41	92	4	anti	anti	ADJ
bptjm-41	92	5	-	-	ADJ
bptjm-41	92	6	infective	infective	ADJ
bptjm-41	92	7	therapy	therapy	NOUN
bptjm-41	92	8	.	.	PUNCT
bptjm-41	93	1	2021;20(3):353	2021;20(3):353	NUM
bptjm-41	93	2	-	-	SYM
bptjm-41	93	3	372	372	NUM
bptjm-41	93	4	.	.	PUNCT
bptjm-41	94	1	doi:10.1080/14787210.2021.1962291	doi:10.1080/14787210.2021.1962291	PROPN
bptjm-41	94	2	3	3	PROPN
bptjm-41	94	3	.	.	PUNCT
bptjm-41	94	4	chou	chou	PROPN
bptjm-41	94	5	ac	ac	PROPN
bptjm-41	94	6	,	,	PUNCT
bptjm-41	94	7	fitch	fitch	PROPN
bptjm-41	94	8	cd	cd	PROPN
bptjm-41	94	9	.	.	PUNCT
bptjm-41	94	10	heme	heme	PROPN
bptjm-41	94	11	polymerase	polymerase	NOUN
bptjm-41	94	12	:	:	PUNCT
bptjm-41	94	13	modulation	modulation	NOUN
bptjm-41	94	14	by	by	ADP
bptjm-41	94	15	chloroquine	chloroquine	ADJ
bptjm-41	94	16	treatment	treatment	NOUN
bptjm-41	94	17	of	of	ADP
bptjm-41	94	18	a	a	DET
bptjm-41	94	19	rodent	rodent	ADJ
bptjm-41	94	20	malaria	malaria	NOUN
bptjm-41	94	21	.	.	PUNCT
bptjm-41	95	1	life	life	NOUN
bptjm-41	95	2	sciences	sciences	PROPN
bptjm-41	95	3	.	.	PUNCT
bptjm-41	96	1	1992;51(26):2073	1992;51(26):2073	NUM
bptjm-41	96	2	-	-	SYM
bptjm-41	96	3	2078	2078	NUM
bptjm-41	96	4	.	.	PUNCT
bptjm-41	97	1	doi:10.1016/0024	doi:10.1016/0024	ADJ
bptjm-41	97	2	-	-	PUNCT
bptjm-41	97	3	3205(92)90158	3205(92)90158	NUM
bptjm-41	97	4	-	-	PUNCT
bptjm-41	97	5	l	l	NOUN
bptjm-41	97	6	4	4	NUM
bptjm-41	97	7	.	.	PUNCT
bptjm-41	97	8	slater	slater	PROPN
bptjm-41	97	9	af	af	PROPN
bptjm-41	97	10	,	,	PUNCT
bptjm-41	97	11	cerami	cerami	PROPN
bptjm-41	97	12	a.	a.	NOUN
bptjm-41	97	13	inhibition	inhibition	NOUN
bptjm-41	97	14	by	by	ADP
bptjm-41	97	15	chloroquine	chloroquine	NOUN
bptjm-41	97	16	of	of	ADP
bptjm-41	97	17	a	a	DET
bptjm-41	97	18	novel	novel	ADJ
bptjm-41	97	19	haem	haem	NOUN
bptjm-41	97	20	polymerase	polymerase	NOUN
bptjm-41	97	21	enzyme	enzyme	NOUN
bptjm-41	97	22	activity	activity	NOUN
bptjm-41	97	23	in	in	ADP
bptjm-41	97	24	malaria	malaria	NOUN
bptjm-41	97	25	trophozoites	trophozoite	NOUN
bptjm-41	97	26	.	.	PUNCT
bptjm-41	98	1	nature	nature	NOUN
bptjm-41	98	2	.	.	PUNCT
bptjm-41	99	1	1992;355(6356):167	1992;355(6356):167	NUM
bptjm-41	99	2	-	-	SYM
bptjm-41	99	3	169	169	NUM
bptjm-41	99	4	.	.	PUNCT
bptjm-41	100	1	doi:10.1038/355167a0	doi:10.1038/355167a0	NOUN
bptjm-41	100	2	5	5	NUM
bptjm-41	100	3	.	.	PUNCT
bptjm-41	101	1	coronado	coronado	PROPN
bptjm-41	101	2	lm	lm	PROPN
bptjm-41	101	3	,	,	PUNCT
bptjm-41	101	4	nadovich	nadovich	NOUN
bptjm-41	101	5	ct	ct	PROPN
bptjm-41	101	6	,	,	PUNCT
bptjm-41	101	7	spadafora	spadafora	PROPN
bptjm-41	101	8	c.	c.	PROPN
bptjm-41	101	9	malarial	malarial	ADJ
bptjm-41	101	10	hemozoin	hemozoin	NOUN
bptjm-41	101	11	:	:	PUNCT
bptjm-41	101	12	from	from	ADP
bptjm-41	101	13	target	target	NOUN
bptjm-41	101	14	to	to	ADP
bptjm-41	101	15	tool	tool	NOUN
bptjm-41	101	16	.	.	PUNCT
bptjm-41	102	1	biochimica	biochimica	PROPN
bptjm-41	102	2	et	et	PROPN
bptjm-41	102	3	biophysica	biophysica	PROPN
bptjm-41	102	4	acta	acta	PROPN
bptjm-41	102	5	(	(	PUNCT
bptjm-41	102	6	bba	bba	NOUN
bptjm-41	102	7	)	)	PUNCT
bptjm-41	102	8	general	general	ADJ
bptjm-41	102	9	subjects	subject	NOUN
bptjm-41	102	10	.	.	PUNCT
bptjm-41	103	1	2014;1840(6):2032	2014;1840(6):2032	NUM
bptjm-41	103	2	-	-	SYM
bptjm-41	103	3	2041	2041	NUM
bptjm-41	103	4	.	.	PUNCT
bptjm-41	104	1	doi:10.1016	doi:10.1016	PROPN
bptjm-41	104	2	/	/	SYM
bptjm-41	104	3	j.bbagen.2014.02.009	j.bbagen.2014.02.009	PROPN
bptjm-41	104	4	6	6	NUM
bptjm-41	104	5	.	.	PUNCT
bptjm-41	105	1	li	li	PROPN
bptjm-41	105	2	w	w	PROPN
bptjm-41	105	3	,	,	PUNCT
bptjm-41	105	4	zou	zou	PROPN
bptjm-41	105	5	z	z	PROPN
bptjm-41	105	6	,	,	PUNCT
bptjm-41	105	7	cai	cai	PROPN
bptjm-41	105	8	y	y	PROPN
bptjm-41	105	9	,	,	PUNCT
bptjm-41	105	10	et	et	PROPN
bptjm-41	105	11	al	al	PROPN
bptjm-41	105	12	.	.	PUNCT
bptjm-41	105	13	low	low	ADJ
bptjm-41	105	14	-	-	PUNCT
bptjm-41	105	15	dose	dose	VERB
bptjm-41	105	16	chloroquine	chloroquine	NOUN
bptjm-41	105	17	treatment	treatment	NOUN
bptjm-41	105	18	extends	extend	VERB
bptjm-41	105	19	the	the	DET
bptjm-41	105	20	lifespan	lifespan	NOUN
bptjm-41	105	21	of	of	ADP
bptjm-41	105	22	aged	aged	ADJ
bptjm-41	105	23	rats	rat	NOUN
bptjm-41	105	24	.	.	PUNCT
bptjm-41	106	1	protein	protein	NOUN
bptjm-41	106	2	&	&	CCONJ
bptjm-41	106	3	cell	cell	NOUN
bptjm-41	106	4	.	.	PUNCT
bptjm-41	107	1	2022;13(6):454	2022;13(6):454	NUM
bptjm-41	107	2	-	-	SYM
bptjm-41	107	3	461	461	NUM
bptjm-41	107	4	.	.	PUNCT
bptjm-41	108	1	doi:10.1007	doi:10.1007	VERB
bptjm-41	108	2	/	/	SYM
bptjm-41	108	3	s13238	s13238	NOUN
bptjm-41	108	4	-	-	PUNCT
bptjm-41	108	5	021	021	NUM
bptjm-41	108	6	-	-	PUNCT
bptjm-41	108	7	00903	00903	NUM
bptjm-41	108	8	-	-	SYM
bptjm-41	108	9	1	1	NUM
bptjm-41	108	10	7	7	NUM
bptjm-41	108	11	.	.	PUNCT
bptjm-41	108	12	sargiacomo	sargiacomo	PROPN
bptjm-41	108	13	c	c	PROPN
bptjm-41	108	14	,	,	PUNCT
bptjm-41	108	15	sotgia	sotgia	PROPN
bptjm-41	108	16	f	f	PROPN
bptjm-41	108	17	,	,	PUNCT
bptjm-41	108	18	lisanti	lisanti	PROPN
bptjm-41	108	19	mp	mp	PROPN
bptjm-41	108	20	.	.	PUNCT
bptjm-41	109	1	covid-19	covid-19	PROPN
bptjm-41	109	2	and	and	CCONJ
bptjm-41	109	3	chronological	chronological	ADJ
bptjm-41	109	4	aging	aging	NOUN
bptjm-41	109	5	:	:	PUNCT
bptjm-41	109	6	senolytics	senolytic	NOUN
bptjm-41	109	7	and	and	CCONJ
bptjm-41	109	8	other	other	ADJ
bptjm-41	109	9	anti	anti	ADJ
bptjm-41	109	10	-	-	ADJ
bptjm-41	109	11	aging	aging	ADJ
bptjm-41	109	12	drugs	drug	NOUN
bptjm-41	109	13	for	for	ADP
bptjm-41	109	14	the	the	DET
bptjm-41	109	15	treatment	treatment	NOUN
bptjm-41	109	16	or	or	CCONJ
bptjm-41	109	17	prevention	prevention	NOUN
bptjm-41	109	18	of	of	ADP
bptjm-41	109	19	corona	corona	PROPN
bptjm-41	109	20	virus	virus	NOUN
bptjm-41	109	21	infection	infection	NOUN
bptjm-41	109	22	?	?	PUNCT
bptjm-41	110	1	aging	aging	NOUN
bptjm-41	110	2	.	.	PUNCT
bptjm-41	111	1	2020;12(8):6511	2020;12(8):6511	PROPN
bptjm-41	111	2	-	-	PUNCT
bptjm-41	111	3	6517	6517	NUM
bptjm-41	111	4	.	.	PUNCT
bptjm-41	112	1	doi:10.18632	doi:10.18632	PROPN
bptjm-41	112	2	/	/	SYM
bptjm-41	112	3	aging.103001	aging.103001	PROPN
bptjm-41	112	4	8	8	NUM
bptjm-41	112	5	.	.	PUNCT
bptjm-41	113	1	kim	kim	PROPN
bptjm-41	113	2	km	km	PROPN
bptjm-41	113	3	,	,	PUNCT
bptjm-41	113	4	noh	noh	PROPN
bptjm-41	113	5	jh	jh	PROPN
bptjm-41	113	6	,	,	PUNCT
bptjm-41	113	7	bodogai	bodogai	PROPN
bptjm-41	113	8	m	m	PROPN
bptjm-41	113	9	,	,	PUNCT
bptjm-41	113	10	et	et	PROPN
bptjm-41	113	11	al	al	PROPN
bptjm-41	113	12	.	.	PUNCT
bptjm-41	113	13	identi	identi	PROPN
bptjm-41	113	14	�	�	PROPN
bptjm-41	113	15	cation	cation	NOUN
bptjm-41	113	16	of	of	ADP
bptjm-41	113	17	senescent	senescent	ADJ
bptjm-41	113	18	cell	cell	NOUN
bptjm-41	113	19	surface	surface	NOUN
bptjm-41	113	20	targetable	targetable	ADJ
bptjm-41	113	21	protein	protein	NOUN
bptjm-41	113	22	dpp4	dpp4	PROPN
bptjm-41	113	23	.	.	PUNCT
bptjm-41	114	1	genes	gene	NOUN
bptjm-41	114	2	&	&	CCONJ
bptjm-41	114	3	development	development	NOUN
bptjm-41	114	4	.	.	PUNCT
bptjm-41	115	1	2017;31(15):1529	2017;31(15):1529	X
bptjm-41	115	2	-	-	SYM
bptjm-41	115	3	1534	1534	NUM
bptjm-41	115	4	.	.	PUNCT
bptjm-41	116	1	doi:10.1101	doi:10.1101	NOUN
bptjm-41	116	2	/	/	SYM
bptjm-41	116	3	gad.302570.117	gad.302570.117	PROPN
bptjm-41	116	4	9	9	NUM
bptjm-41	116	5	.	.	PUNCT
bptjm-41	116	6	guy	guy	PROPN
bptjm-41	116	7	jl	jl	PROPN
bptjm-41	116	8	,	,	PUNCT
bptjm-41	116	9	lambert	lambert	PROPN
bptjm-41	116	10	dw	dw	PROPN
bptjm-41	116	11	,	,	PUNCT
bptjm-41	116	12	turner	turner	PROPN
bptjm-41	116	13	aj	aj	PROPN
bptjm-41	116	14	,	,	PUNCT
bptjm-41	116	15	porter	porter	PROPN
bptjm-41	116	16	ke	ke	PROPN
bptjm-41	116	17	.	.	PUNCT
bptjm-41	117	1	functional	functional	ADJ
bptjm-41	117	2	angiotensin	angiotensin	NOUN
bptjm-41	117	3	-	-	PUNCT
bptjm-41	117	4	converting	convert	VERB
bptjm-41	117	5	enzyme	enzyme	NOUN
bptjm-41	117	6	2	2	NUM
bptjm-41	117	7	is	be	AUX
bptjm-41	117	8	expressed	express	VERB
bptjm-41	117	9	in	in	ADP
bptjm-41	117	10	human	human	ADJ
bptjm-41	117	11	cardiac	cardiac	ADJ
bptjm-41	117	12	myo	myo	PROPN
bptjm-41	117	13	�	�	PROPN
bptjm-41	117	14	broblasts	broblast	NOUN
bptjm-41	117	15	.	.	PUNCT
bptjm-41	118	1	experimental	experimental	ADJ
bptjm-41	118	2	physiology	physiology	NOUN
bptjm-41	118	3	.	.	PUNCT
bptjm-41	119	1	2008;93(5):579	2008;93(5):579	NUM
bptjm-41	119	2	-	-	SYM
bptjm-41	119	3	588	588	NUM
bptjm-41	119	4	.	.	PUNCT
bptjm-41	119	5	doi:10.1113	doi:10.1113	NOUN
bptjm-41	119	6	/	/	SYM
bptjm-41	119	7	expphysiol.2007.040139	expphysiol.2007.040139	PROPN
bptjm-41	119	8	10	10	NUM
bptjm-41	119	9	.	.	PUNCT
bptjm-41	120	1	cavalcante	cavalcante	PROPN
bptjm-41	120	2	mb	mb	PROPN
bptjm-41	120	3	,	,	PUNCT
bptjm-41	120	4	saccon	saccon	NOUN
bptjm-41	120	5	td	td	NOUN
bptjm-41	120	6	,	,	PUNCT
bptjm-41	120	7	nunes	nunes	PROPN
bptjm-41	120	8	adc	adc	PROPN
bptjm-41	120	9	,	,	PUNCT
bptjm-41	120	10	et	et	PROPN
bptjm-41	120	11	al	al	PROPN
bptjm-41	120	12	.	.	PROPN
bptjm-41	120	13	dasatinib	dasatinib	NOUN
bptjm-41	120	14	plus	plus	CCONJ
bptjm-41	120	15	quercetin	quercetin	NOUN
bptjm-41	120	16	prevents	prevent	VERB
bptjm-41	120	17	uterine	uterine	ADJ
bptjm-41	120	18	age	age	NOUN
bptjm-41	120	19	-	-	PUNCT
bptjm-41	120	20	related	relate	VERB
bptjm-41	120	21	dysfunction	dysfunction	NOUN
bptjm-41	120	22	and	and	CCONJ
bptjm-41	120	23	�	�	NOUN
bptjm-41	120	24	brosis	brosis	NOUN
bptjm-41	120	25	in	in	ADP
bptjm-41	120	26	mice	mouse	NOUN
bptjm-41	120	27	.	.	PUNCT
bptjm-41	121	1	aging	age	VERB
bptjm-41	121	2	.	.	PUNCT
bptjm-41	122	1	2020;12(3):2711	2020;12(3):2711	NOUN
bptjm-41	122	2	-	-	SYM
bptjm-41	122	3	2722	2722	NUM
bptjm-41	122	4	.	.	PUNCT
bptjm-41	123	1	doi:10.18632	doi:10.18632	PROPN
bptjm-41	123	2	/	/	SYM
bptjm-41	123	3	aging.102772	aging.102772	PROPN
bptjm-41	123	4	11	11	NUM
bptjm-41	123	5	.	.	PUNCT
bptjm-41	124	1	zoico	zoico	PROPN
bptjm-41	124	2	e	e	PROPN
bptjm-41	124	3	,	,	PUNCT
bptjm-41	124	4	nori	nori	PROPN
bptjm-41	124	5	n	n	PROPN
bptjm-41	124	6	,	,	PUNCT
bptjm-41	124	7	darra	darra	PROPN
bptjm-41	124	8	e	e	PROPN
bptjm-41	124	9	,	,	PUNCT
bptjm-41	124	10	et	et	PROPN
bptjm-41	124	11	al	al	PROPN
bptjm-41	124	12	.	.	PROPN
bptjm-41	125	1	senolytic	senolytic	PROPN
bptjm-41	125	2	e	e	NOUN
bptjm-41	125	3	�	�	NOUN
bptjm-41	125	4	ects	ect	NOUN
bptjm-41	125	5	of	of	ADP
bptjm-41	125	6	quercetin	quercetin	NOUN
bptjm-41	125	7	in	in	ADP
bptjm-41	125	8	an	an	DET
bptjm-41	125	9	in	in	X
bptjm-41	125	10	vitro	vitro	X
bptjm-41	125	11	model	model	NOUN
bptjm-41	125	12	of	of	ADP
bptjm-41	125	13	pre	pre	ADJ
bptjm-41	125	14	-	-	ADJ
bptjm-41	125	15	adipocytes	adipocyte	NOUN
bptjm-41	125	16	and	and	CCONJ
bptjm-41	125	17	adipocytes	adipocyte	NOUN
bptjm-41	125	18	induced	induced	ADJ
bptjm-41	125	19	senescence	senescence	NOUN
bptjm-41	125	20	.	.	PUNCT
bptjm-41	126	1	scientific	scientific	ADJ
bptjm-41	126	2	reports	report	NOUN
bptjm-41	126	3	.	.	PUNCT
bptjm-41	127	1	2021;11(1	2021;11(1	NUM
bptjm-41	127	2	)	)	PUNCT
bptjm-41	127	3	.	.	PUNCT
bptjm-41	128	1	doi:10.1038	doi:10.1038	NOUN
bptjm-41	128	2	/	/	SYM
bptjm-41	128	3	s41598	s41598	NOUN
bptjm-41	128	4	-	-	PUNCT
bptjm-41	128	5	021	021	NUM
bptjm-41	128	6	-	-	PUNCT
bptjm-41	128	7	02544	02544	NUM
bptjm-41	128	8	-	-	SYM
bptjm-41	128	9	0	0	NUM
bptjm-41	128	10	12	12	NUM
bptjm-41	128	11	.	.	PUNCT
bptjm-41	129	1	kurz	kurz	PROPN
bptjm-41	129	2	dj	dj	PROPN
bptjm-41	129	3	,	,	PUNCT
bptjm-41	129	4	decary	decary	PROPN
bptjm-41	129	5	s	s	PROPN
bptjm-41	129	6	,	,	PUNCT
bptjm-41	129	7	hong	hong	PROPN
bptjm-41	129	8	y	y	PROPN
bptjm-41	129	9	,	,	PUNCT
bptjm-41	129	10	erusalimsky	erusalimsky	PROPN
bptjm-41	129	11	jd	jd	PROPN
bptjm-41	129	12	.	.	PUNCT
bptjm-41	129	13	senescence	senescence	NOUN
bptjm-41	129	14	-	-	PUNCT
bptjm-41	129	15	associated	associate	VERB
bptjm-41	129	16	(	(	PUNCT
bptjm-41	129	17	beta)-galactosidase	beta)-galactosidase	PROPN
bptjm-41	129	18	re	re	NOUN
bptjm-41	129	19	�	�	PROPN
bptjm-41	129	20	ects	ect	VERB
bptjm-41	129	21	an	an	DET
bptjm-41	129	22	increase	increase	NOUN
bptjm-41	129	23	in	in	ADP
bptjm-41	129	24	lysosomal	lysosomal	ADJ
bptjm-41	129	25	mass	mass	NOUN
bptjm-41	129	26	during	during	ADP
bptjm-41	129	27	replicative	replicative	ADJ
bptjm-41	129	28	ageing	ageing	NOUN
bptjm-41	129	29	of	of	ADP
bptjm-41	129	30	human	human	ADJ
bptjm-41	129	31	endothelial	endothelial	ADJ
bptjm-41	129	32	cells	cell	NOUN
bptjm-41	129	33	.	.	PUNCT
bptjm-41	130	1	journal	journal	NOUN
bptjm-41	130	2	of	of	ADP
bptjm-41	130	3	cell	cell	NOUN
bptjm-41	130	4	science	science	NOUN
bptjm-41	130	5	.	.	PUNCT
bptjm-41	131	1	2000;113(20):3613	2000;113(20):3613	NUM
bptjm-41	131	2	-	-	SYM
bptjm-41	131	3	3622	3622	NUM
bptjm-41	131	4	.	.	PUNCT
bptjm-41	132	1	doi:10.1242	doi:10.1242	NOUN
bptjm-41	132	2	/	/	SYM
bptjm-41	132	3	jcs.113.20.3613	jcs.113.20.3613	PROPN
bptjm-41	132	4	13	13	NUM
bptjm-41	132	5	.	.	PUNCT
bptjm-41	133	1	gautret	gautret	VERB
bptjm-41	133	2	p	p	NOUN
bptjm-41	133	3	,	,	PUNCT
bptjm-41	133	4	lagier	lagier	PROPN
bptjm-41	133	5	j	j	PROPN
bptjm-41	133	6	-	-	PROPN
bptjm-41	133	7	c	c	PROPN
bptjm-41	133	8	,	,	PUNCT
bptjm-41	133	9	parola	parola	PROPN
bptjm-41	133	10	p	p	X
bptjm-41	133	11	,	,	PUNCT
bptjm-41	133	12	et	et	PROPN
bptjm-41	133	13	al	al	PROPN
bptjm-41	133	14	.	.	PROPN
bptjm-41	133	15	hydroxychloroquine	hydroxychloroquine	PROPN
bptjm-41	133	16	and	and	CCONJ
bptjm-41	133	17	azithromycin	azithromycin	VERB
bptjm-41	133	18	as	as	ADP
bptjm-41	133	19	a	a	DET
bptjm-41	133	20	treatment	treatment	NOUN
bptjm-41	133	21	of	of	ADP
bptjm-41	133	22	covid-19	covid-19	PROPN
bptjm-41	133	23	:	:	PUNCT
bptjm-41	133	24	results	result	NOUN
bptjm-41	133	25	of	of	ADP
bptjm-41	133	26	an	an	DET
bptjm-41	133	27	open	open	ADJ
bptjm-41	133	28	-	-	PUNCT
bptjm-41	133	29	label	label	NOUN
bptjm-41	133	30	non	non	ADJ
bptjm-41	133	31	-	-	ADJ
bptjm-41	133	32	randomized	randomized	ADJ
bptjm-41	133	33	clinical	clinical	ADJ
bptjm-41	133	34	trial	trial	NOUN
bptjm-41	133	35	.	.	PUNCT
bptjm-41	134	1	international	international	ADJ
bptjm-41	134	2	journal	journal	PROPN
bptjm-41	134	3	of	of	ADP
bptjm-41	134	4	antimicrobial	antimicrobial	ADJ
bptjm-41	134	5	agents	agent	NOUN
bptjm-41	134	6	.	.	PUNCT
bptjm-41	135	1	2020	2020	NUM
bptjm-41	135	2	.	.	PUNCT
bptjm-41	136	1	doi:10.1101/2020.03.16.20037135	doi:10.1101/2020.03.16.20037135	PROPN
bptjm-41	136	2	14	14	NUM
bptjm-41	136	3	.	.	PUNCT
bptjm-41	137	1	boulware	boulware	PROPN
bptjm-41	137	2	dr	dr	PROPN
bptjm-41	137	3	,	,	PUNCT
bptjm-41	137	4	pullen	pullen	PROPN
bptjm-41	137	5	mf	mf	PROPN
bptjm-41	137	6	,	,	PUNCT
bptjm-41	137	7	bangdiwala	bangdiwala	NOUN
bptjm-41	137	8	as	as	ADP
bptjm-41	137	9	,	,	PUNCT
bptjm-41	137	10	et	et	PROPN
bptjm-41	137	11	al	al	PROPN
bptjm-41	137	12	.	.	PUNCT
bptjm-41	138	1	a	a	DET
bptjm-41	138	2	randomized	randomized	ADJ
bptjm-41	138	3	trial	trial	NOUN
bptjm-41	138	4	of	of	ADP
bptjm-41	138	5	hydroxychloroquine	hydroxychloroquine	NOUN
bptjm-41	138	6	as	as	ADP
bptjm-41	138	7	postexposure	postexposure	NOUN
bptjm-41	138	8	prophylaxis	prophylaxis	NOUN
bptjm-41	138	9	for	for	ADP
bptjm-41	138	10	covid-19	covid-19	PROPN
bptjm-41	138	11	.	.	PUNCT
bptjm-41	138	12	new	new	PROPN
bptjm-41	138	13	england	england	PROPN
bptjm-41	138	14	journal	journal	PROPN
bptjm-41	138	15	of	of	ADP
bptjm-41	138	16	medicine	medicine	NOUN
bptjm-41	138	17	.	.	PUNCT
bptjm-41	139	1	2020;383(6):517	2020;383(6):517	PROPN
bptjm-41	139	2	-	-	SYM
bptjm-41	139	3	525	525	NUM
bptjm-41	139	4	.	.	PUNCT
bptjm-41	139	5	doi:10.1056	doi:10.1056	PROPN
bptjm-41	139	6	/	/	SYM
bptjm-41	139	7	nejmoa2016638	nejmoa2016638	PROPN
bptjm-41	139	8	15	15	NUM
bptjm-41	139	9	.	.	PUNCT
bptjm-41	140	1	tang	tang	PROPN
bptjm-41	140	2	w	w	PROPN
bptjm-41	140	3	,	,	PUNCT
bptjm-41	140	4	cao	cao	PROPN
bptjm-41	140	5	z	z	PROPN
bptjm-41	140	6	,	,	PUNCT
bptjm-41	140	7	han	han	PROPN
bptjm-41	140	8	m	m	PROPN
bptjm-41	140	9	,	,	PUNCT
bptjm-41	140	10	et	et	PROPN
bptjm-41	140	11	al	al	PROPN
bptjm-41	140	12	.	.	PROPN
bptjm-41	140	13	hydroxychloroquine	hydroxychloroquine	PROPN
bptjm-41	140	14	in	in	ADP
bptjm-41	140	15	patients	patient	NOUN
bptjm-41	140	16	with	with	ADP
bptjm-41	140	17	mainly	mainly	ADV
bptjm-41	140	18	mild	mild	ADJ
bptjm-41	140	19	to	to	ADP
bptjm-41	140	20	moderate	moderate	ADJ
bptjm-41	140	21	coronavirus	coronavirus	NOUN
bptjm-41	140	22	disease	disease	NOUN
bptjm-41	140	23	2019	2019	NUM
bptjm-41	140	24	:	:	PUNCT
bptjm-41	140	25	open	open	ADJ
bptjm-41	140	26	label	label	NOUN
bptjm-41	140	27	,	,	PUNCT
bptjm-41	140	28	randomised	randomise	VERB
bptjm-41	140	29	controlled	control	VERB
bptjm-41	140	30	trial	trial	NOUN
bptjm-41	140	31	.	.	PUNCT
bptjm-41	141	1	bmj	bmj	PROPN
bptjm-41	141	2	.	.	PUNCT
bptjm-41	142	1	2020	2020	NUM
bptjm-41	142	2	:	:	PUNCT
bptjm-41	142	3	m1849	m1849	NOUN
bptjm-41	142	4	.	.	PUNCT
bptjm-41	143	1	doi:10.1136	doi:10.1136	NOUN
bptjm-41	143	2	/	/	SYM
bptjm-41	143	3	bmj.m1849	bmj.m1849	X
bptjm-41	143	4	16.he	16.he	NUM
bptjm-41	143	5	w	w	NOUN
bptjm-41	143	6	,	,	PUNCT
bptjm-41	143	7	gao	gao	PROPN
bptjm-41	143	8	y	y	PROPN
bptjm-41	143	9	,	,	PUNCT
bptjm-41	143	10	zhou	zhou	PROPN
bptjm-41	143	11	j	j	PROPN
bptjm-41	143	12	,	,	PUNCT
bptjm-41	143	13	shi	shi	PROPN
bptjm-41	143	14	y	y	PROPN
bptjm-41	143	15	,	,	PUNCT
bptjm-41	143	16	xia	xia	PROPN
bptjm-41	144	1	d	d	PROPN
bptjm-41	144	2	,	,	PUNCT
bptjm-41	144	3	shen	shen	PROPN
bptjm-41	144	4	h	h	NOUN
bptjm-41	144	5	-	-	PUNCT
bptjm-41	144	6	m.	m.	NOUN
bptjm-41	144	7	friend	friend	NOUN
bptjm-41	144	8	or	or	CCONJ
bptjm-41	144	9	foe	foe	NOUN
bptjm-41	144	10	?	?	PUNCT
bptjm-41	145	1	implication	implication	NOUN
bptjm-41	145	2	of	of	ADP
bptjm-41	145	3	the	the	DET
bptjm-41	145	4	autophagy	autophagy	ADJ
bptjm-41	145	5	-	-	PUNCT
bptjm-41	145	6	lysosome	lysosome	NOUN
bptjm-41	145	7	pathway	pathway	NOUN
bptjm-41	145	8	in	in	ADP
bptjm-41	145	9	sars	sar	NOUN
bptjm-41	145	10	-	-	PUNCT
bptjm-41	145	11	cov-2	cov-2	PART
bptjm-41	145	12	infection	infection	NOUN
bptjm-41	145	13	and	and	CCONJ
bptjm-41	145	14	covid-19	covid-19	PROPN
bptjm-41	145	15	.	.	PUNCT
bptjm-41	145	16	international	international	PROPN
bptjm-41	145	17	journal	journal	PROPN
bptjm-41	145	18	of	of	ADP
bptjm-41	145	19	biological	biological	ADJ
bptjm-41	145	20	sciences	science	NOUN
bptjm-41	145	21	.	.	PUNCT
bptjm-41	146	1	2022;18(12):4690	2022;18(12):4690	NUM
bptjm-41	146	2	-	-	SYM
bptjm-41	146	3	4703	4703	NUM
bptjm-41	146	4	.	.	PUNCT
bptjm-41	147	1	doi:10.7150	doi:10.7150	PROPN
bptjm-41	147	2	/	/	SYM
bptjm-41	148	1	ijbs.72544	ijbs.72544	PROPN
bptjm-41	148	2	berkeley	berkeley	PROPN
bptjm-41	148	3	pharma	pharma	PROPN
bptjm-41	148	4	tech	tech	NOUN
bptjm-41	148	5	journal	journal	NOUN
bptjm-41	148	6	of	of	ADP
bptjm-41	148	7	medicine	medicine	NOUN
bptjm-41	148	8	|	|	ADV
bptjm-41	148	9	7	7	NUM
bptjm-41	148	10	17	17	NUM
bptjm-41	148	11	.	.	PUNCT
bptjm-41	149	1	doeppner	doeppner	NOUN
bptjm-41	149	2	tr	tr	VERB
bptjm-41	149	3	,	,	PUNCT
bptjm-41	149	4	coman	coman	PROPN
bptjm-41	149	5	c	c	PROPN
bptjm-41	149	6	,	,	PUNCT
bptjm-41	149	7	burdusel	burdusel	PROPN
bptjm-41	149	8	d	d	PROPN
bptjm-41	149	9	,	,	PUNCT
bptjm-41	149	10	et	et	PROPN
bptjm-41	149	11	al	al	PROPN
bptjm-41	149	12	.	.	PUNCT
bptjm-41	150	1	long	long	ADJ
bptjm-41	150	2	-	-	PUNCT
bptjm-41	150	3	term	term	NOUN
bptjm-41	150	4	treatment	treatment	NOUN
bptjm-41	150	5	with	with	ADP
bptjm-41	150	6	chloroquine	chloroquine	NOUN
bptjm-41	150	7	increases	increase	NOUN
bptjm-41	150	8	lifespan	lifespan	VERB
bptjm-41	150	9	in	in	ADP
bptjm-41	150	10	middle	middle	ADJ
bptjm-41	150	11	-	-	PUNCT
bptjm-41	150	12	aged	aged	ADJ
bptjm-41	150	13	male	male	ADJ
bptjm-41	150	14	mice	mouse	NOUN
bptjm-41	150	15	possibly	possibly	ADV
bptjm-41	150	16	via	via	ADP
bptjm-41	150	17	autophagy	autophagy	ADJ
bptjm-41	150	18	modulation	modulation	NOUN
bptjm-41	150	19	,	,	PUNCT
bptjm-41	150	20	proteasome	proteasome	NOUN
bptjm-41	150	21	inhibition	inhibition	NOUN
bptjm-41	150	22	and	and	CCONJ
bptjm-41	150	23	glycogen	glycogen	NOUN
bptjm-41	150	24	metabolism	metabolism	NOUN
bptjm-41	150	25	.	.	PUNCT
bptjm-41	151	1	aging	aging	NOUN
bptjm-41	151	2	.	.	PUNCT
bptjm-41	152	1	2022;14(10):4195	2022;14(10):4195	NUM
bptjm-41	152	2	-	-	SYM
bptjm-41	152	3	4210	4210	NUM
bptjm-41	152	4	.	.	PUNCT
bptjm-41	153	1	doi:10.18632	doi:10.18632	PROPN
bptjm-41	153	2	/	/	SYM
bptjm-41	153	3	aging.204069	aging.204069	PROPN
bptjm-41	153	4	18	18	NUM
bptjm-41	153	5	.	.	PUNCT
bptjm-41	154	1	filfan	filfan	PROPN
bptjm-41	154	2	m	m	VERB
bptjm-41	154	3	,	,	PUNCT
bptjm-41	154	4	olaru	olaru	PROPN
bptjm-41	154	5	a	a	NOUN
bptjm-41	154	6	,	,	PUNCT
bptjm-41	154	7	udristoiu	udristoiu	NOUN
bptjm-41	154	8	i	i	PRON
bptjm-41	154	9	,	,	PUNCT
bptjm-41	154	10	et	et	PROPN
bptjm-41	154	11	al	al	PROPN
bptjm-41	154	12	.	.	PUNCT
bptjm-41	155	1	long	long	ADJ
bptjm-41	155	2	-	-	PUNCT
bptjm-41	155	3	term	term	NOUN
bptjm-41	155	4	treatment	treatment	NOUN
bptjm-41	155	5	with	with	ADP
bptjm-41	155	6	spermidine	spermidine	NOUN
bptjm-41	155	7	increases	increase	VERB
bptjm-41	155	8	health	health	NOUN
bptjm-41	155	9	span	span	NOUN
bptjm-41	155	10	of	of	ADP
bptjm-41	155	11	middle	middle	ADJ
bptjm-41	155	12	-	-	PUNCT
bptjm-41	155	13	aged	aged	ADJ
bptjm-41	155	14	sprague	sprague	NOUN
bptjm-41	155	15	-	-	PUNCT
bptjm-41	155	16	dawley	dawley	NOUN
bptjm-41	155	17	male	male	ADJ
bptjm-41	155	18	rats	rat	NOUN
bptjm-41	155	19	.	.	PUNCT
bptjm-41	156	1	geroscience	geroscience	NOUN
bptjm-41	156	2	.	.	PUNCT
bptjm-41	157	1	2020;42(3):937	2020;42(3):937	NUM
bptjm-41	157	2	-	-	SYM
bptjm-41	157	3	949	949	NUM
bptjm-41	157	4	.	.	PUNCT
bptjm-41	158	1	doi:10.1007	doi:10.1007	VERB
bptjm-41	158	2	/	/	SYM
bptjm-41	158	3	s11357	s11357	NOUN
bptjm-41	158	4	-	-	PUNCT
bptjm-41	158	5	020	020	NUM
bptjm-41	158	6	-	-	PUNCT
bptjm-41	158	7	00173	00173	NUM
bptjm-41	158	8	-	-	PUNCT
bptjm-41	158	9	5	5	NUM
bptjm-41	158	10	19	19	NUM
bptjm-41	158	11	.	.	PUNCT
bptjm-41	159	1	eisenberg	eisenberg	PROPN
bptjm-41	159	2	t	t	PROPN
bptjm-41	159	3	,	,	PUNCT
bptjm-41	159	4	knauer	knauer	NOUN
bptjm-41	159	5	h	h	PROPN
bptjm-41	159	6	,	,	PUNCT
bptjm-41	159	7	schauer	schauer	NOUN
bptjm-41	159	8	a	a	NOUN
bptjm-41	159	9	,	,	PUNCT
bptjm-41	159	10	et	et	PROPN
bptjm-41	159	11	al	al	PROPN
bptjm-41	159	12	.	.	PROPN
bptjm-41	159	13	induction	induction	NOUN
bptjm-41	159	14	of	of	ADP
bptjm-41	159	15	autophagy	autophagy	NOUN
bptjm-41	159	16	by	by	ADP
bptjm-41	159	17	spermidine	spermidine	NOUN
bptjm-41	159	18	promotes	promote	VERB
bptjm-41	159	19	longevity	longevity	NOUN
bptjm-41	159	20	.	.	PUNCT
bptjm-41	160	1	nature	nature	NOUN
bptjm-41	160	2	cell	cell	NOUN
bptjm-41	160	3	biology	biology	NOUN
bptjm-41	160	4	.	.	PUNCT
bptjm-41	161	1	2009;11(11):1305	2009;11(11):1305	NUM
bptjm-41	161	2	-	-	SYM
bptjm-41	161	3	1314	1314	NUM
bptjm-41	161	4	.	.	PUNCT
bptjm-41	162	1	doi:10.1038	doi:10.1038	NOUN
bptjm-41	162	2	/	/	SYM
bptjm-41	162	3	ncb1975	ncb1975	NOUN
bptjm-41	162	4	20	20	NUM
bptjm-41	162	5	.	.	PUNCT
bptjm-41	163	1	eisenberg	eisenberg	PROPN
bptjm-41	163	2	t	t	PROPN
bptjm-41	163	3	,	,	PUNCT
bptjm-41	163	4	abdellatif	abdellatif	NOUN
bptjm-41	163	5	m	m	PROPN
bptjm-41	163	6	,	,	PUNCT
bptjm-41	163	7	schroeder	schroeder	PROPN
bptjm-41	163	8	s	s	PROPN
bptjm-41	163	9	,	,	PUNCT
bptjm-41	163	10	et	et	PROPN
bptjm-41	163	11	al	al	PROPN
bptjm-41	163	12	.	.	PROPN
bptjm-41	163	13	cardioprotection	cardioprotection	PROPN
bptjm-41	163	14	and	and	CCONJ
bptjm-41	163	15	lifespan	lifespan	NOUN
bptjm-41	163	16	extension	extension	NOUN
bptjm-41	163	17	by	by	ADP
bptjm-41	163	18	the	the	DET
bptjm-41	163	19	natural	natural	ADJ
bptjm-41	163	20	polyamine	polyamine	NOUN
bptjm-41	163	21	spermidine	spermidine	NOUN
bptjm-41	163	22	.	.	PUNCT
bptjm-41	164	1	nature	nature	NOUN
bptjm-41	164	2	medicine	medicine	NOUN
bptjm-41	164	3	.	.	PUNCT
bptjm-41	165	1	2016;22(12):1428	2016;22(12):1428	NUM
bptjm-41	165	2	-	-	SYM
bptjm-41	165	3	1438	1438	NUM
bptjm-41	165	4	.	.	PUNCT
bptjm-41	166	1	doi:10.1038	doi:10.1038	NOUN
bptjm-41	166	2	/	/	SYM
bptjm-41	166	3	nm.4222	nm.4222	PROPN
bptjm-41	166	4	21	21	NUM
bptjm-41	166	5	.	.	PUNCT
bptjm-41	167	1	mauthe	mauthe	PROPN
bptjm-41	167	2	m	m	PROPN
bptjm-41	167	3	,	,	PUNCT
bptjm-41	167	4	orhon	orhon	PROPN
bptjm-41	167	5	i	i	PROPN
bptjm-41	167	6	,	,	PUNCT
bptjm-41	167	7	rocchi	rocchi	PROPN
bptjm-41	167	8	c	c	PROPN
bptjm-41	167	9	,	,	PUNCT
bptjm-41	167	10	et	et	PROPN
bptjm-41	167	11	al	al	PROPN
bptjm-41	167	12	.	.	PROPN
bptjm-41	167	13	chloroquine	chloroquine	PROPN
bptjm-41	167	14	inhibits	inhibit	VERB
bptjm-41	167	15	autophagic	autophagic	PROPN
bptjm-41	167	16	�	�	PROPN
bptjm-41	167	17	ux	ux	PROPN
bptjm-41	167	18	by	by	ADP
bptjm-41	167	19	decreasing	decrease	VERB
bptjm-41	167	20	autophagosome	autophagosome	NOUN
bptjm-41	167	21	-	-	PUNCT
bptjm-41	167	22	lysosome	lysosome	NOUN
bptjm-41	167	23	fusion	fusion	NOUN
bptjm-41	167	24	.	.	PUNCT
bptjm-41	168	1	autophagy	autophagy	ADV
bptjm-41	168	2	.	.	PUNCT
bptjm-41	169	1	2018;14(8):1435	2018;14(8):1435	NUM
bptjm-41	169	2	-	-	SYM
bptjm-41	169	3	1455	1455	NUM
bptjm-41	169	4	.	.	PUNCT
bptjm-41	170	1	doi:10.1080/15548627.2018.1474314	doi:10.1080/15548627.2018.1474314	PROPN
bptjm-41	170	2	22	22	NUM
bptjm-41	170	3	.	.	PUNCT
bptjm-41	171	1	yoshii	yoshii	PROPN
bptjm-41	171	2	sr	sr	PROPN
bptjm-41	171	3	,	,	PUNCT
bptjm-41	171	4	mizushima	mizushima	PROPN
bptjm-41	171	5	n.	n.	PROPN
bptjm-41	171	6	monitoring	monitoring	NOUN
bptjm-41	171	7	and	and	CCONJ
bptjm-41	171	8	measuring	measure	VERB
bptjm-41	171	9	autophagy	autophagy	NOUN
bptjm-41	171	10	.	.	PUNCT
bptjm-41	172	1	international	international	ADJ
bptjm-41	172	2	journal	journal	NOUN
bptjm-41	172	3	of	of	ADP
bptjm-41	172	4	molecular	molecular	ADJ
bptjm-41	172	5	sciences	science	NOUN
bptjm-41	172	6	.	.	PUNCT
bptjm-41	173	1	2017;18(9):1865	2017;18(9):1865	NUM
bptjm-41	173	2	.	.	PUNCT
bptjm-41	174	1	doi:10.3390	doi:10.3390	NOUN
bptjm-41	174	2	/	/	SYM
bptjm-41	174	3	ijms18091865	ijms18091865	PROPN
bptjm-41	174	4	23	23	NUM
bptjm-41	174	5	.	.	PUNCT
bptjm-41	175	1	brown	brown	PROPN
bptjm-41	175	2	-	-	PUNCT
bptjm-41	175	3	borg	borg	PROPN
bptjm-41	175	4	hm	hm	NOUN
bptjm-41	175	5	,	,	PUNCT
bptjm-41	175	6	bartke	bartke	PROPN
bptjm-41	175	7	a.	a.	PROPN
bptjm-41	175	8	gh	gh	PROPN
bptjm-41	175	9	and	and	CCONJ
bptjm-41	175	10	igf1	igf1	PROPN
bptjm-41	175	11	:	:	PUNCT
bptjm-41	175	12	roles	role	NOUN
bptjm-41	175	13	in	in	ADP
bptjm-41	175	14	energy	energy	NOUN
bptjm-41	175	15	metabolism	metabolism	NOUN
bptjm-41	175	16	of	of	ADP
bptjm-41	175	17	long	long	ADV
bptjm-41	175	18	-	-	PUNCT
bptjm-41	175	19	living	live	VERB
bptjm-41	175	20	gh	gh	PROPN
bptjm-41	175	21	mutant	mutant	ADJ
bptjm-41	175	22	mice	mouse	NOUN
bptjm-41	175	23	.	.	PUNCT
bptjm-41	176	1	the	the	DET
bptjm-41	176	2	journals	journal	NOUN
bptjm-41	176	3	of	of	ADP
bptjm-41	176	4	gerontology	gerontology	NOUN
bptjm-41	176	5	series	series	PROPN
bptjm-41	176	6	a	a	PRON
bptjm-41	176	7	:	:	PUNCT
bptjm-41	176	8	biological	biological	ADJ
bptjm-41	176	9	sciences	science	NOUN
bptjm-41	176	10	and	and	CCONJ
bptjm-41	176	11	medical	medical	ADJ
bptjm-41	176	12	sciences	science	NOUN
bptjm-41	176	13	.	.	PUNCT
bptjm-41	177	1	2012;67a(6):652	2012;67a(6):652	X
bptjm-41	177	2	-	-	SYM
bptjm-41	177	3	660	660	NUM
bptjm-41	177	4	.	.	PUNCT
bptjm-41	177	5	doi:10.1093	doi:10.1093	NOUN
bptjm-41	177	6	/	/	SYM
bptjm-41	177	7	gerona	gerona	PROPN
bptjm-41	177	8	/	/	SYM
bptjm-41	177	9	gls086	gls086	PROPN
bptjm-41	177	10	24	24	NUM
bptjm-41	177	11	.	.	PUNCT
bptjm-41	178	1	junnila	junnila	PROPN
bptjm-41	178	2	rk	rk	PROPN
bptjm-41	178	3	,	,	PUNCT
bptjm-41	178	4	list	list	NOUN
bptjm-41	178	5	eo	eo	PROPN
bptjm-41	178	6	,	,	PUNCT
bptjm-41	178	7	berryman	berryman	PROPN
bptjm-41	178	8	de	de	PROPN
bptjm-41	178	9	,	,	PUNCT
bptjm-41	178	10	murrey	murrey	PROPN
bptjm-41	178	11	jw	jw	PROPN
bptjm-41	178	12	,	,	PUNCT
bptjm-41	178	13	kopchick	kopchick	PROPN
bptjm-41	178	14	jj	jj	PROPN
bptjm-41	178	15	.	.	PUNCT
bptjm-41	179	1	the	the	DET
bptjm-41	179	2	gh	gh	PROPN
bptjm-41	179	3	/	/	SYM
bptjm-41	179	4	igf-1	igf-1	NOUN
bptjm-41	179	5	axis	axis	NOUN
bptjm-41	179	6	in	in	ADP
bptjm-41	179	7	ageing	ageing	NOUN
bptjm-41	179	8	and	and	CCONJ
bptjm-41	179	9	longevity	longevity	NOUN
bptjm-41	179	10	.	.	PUNCT
bptjm-41	180	1	nature	nature	NOUN
bptjm-41	180	2	reviews	review	VERB
bptjm-41	180	3	endocrinology	endocrinology	NOUN
bptjm-41	180	4	.	.	PUNCT
bptjm-41	181	1	2013;9(6):366	2013;9(6):366	X
bptjm-41	181	2	-	-	SYM
bptjm-41	181	3	376	376	NUM
bptjm-41	181	4	.	.	PUNCT
bptjm-41	182	1	doi:10.1038	doi:10.1038	PROPN
bptjm-41	182	2	/	/	SYM
bptjm-41	182	3	nrendo.2013.67	nrendo.2013.67	PROPN
bptjm-41	182	4	25	25	NUM
bptjm-41	182	5	.	.	PUNCT
bptjm-41	183	1	olivecrona	olivecrona	PROPN
bptjm-41	183	2	h	h	PROPN
bptjm-41	183	3	,	,	PUNCT
bptjm-41	183	4	hilding	hilde	VERB
bptjm-41	183	5	a	a	DET
bptjm-41	183	6	,	,	PUNCT
bptjm-41	183	7	ekström	ekström	ADJ
bptjm-41	183	8	christina	christina	PROPN
bptjm-41	183	9	,	,	PUNCT
bptjm-41	183	10	et	et	PROPN
bptjm-41	183	11	al	al	PROPN
bptjm-41	183	12	.	.	PROPN
bptjm-41	183	13	acute	acute	PROPN
bptjm-41	183	14	and	and	CCONJ
bptjm-41	183	15	short	short	ADJ
bptjm-41	183	16	-	-	PUNCT
bptjm-41	183	17	term	term	NOUN
bptjm-41	183	18	e	e	NOUN
bptjm-41	183	19	�	�	NOUN
bptjm-41	183	20	ects	ect	NOUN
bptjm-41	183	21	of	of	ADP
bptjm-41	183	22	growth	growth	NOUN
bptjm-41	183	23	hormone	hormone	NOUN
bptjm-41	183	24	on	on	ADP
bptjm-41	183	25	insulin	insulin	NOUN
bptjm-41	183	26	-	-	PUNCT
bptjm-41	183	27	like	like	ADJ
bptjm-41	183	28	growth	growth	NOUN
bptjm-41	183	29	factors	factor	NOUN
bptjm-41	183	30	and	and	CCONJ
bptjm-41	183	31	their	their	PRON
bptjm-41	183	32	binding	bind	VERB
bptjm-41	183	33	proteins	protein	NOUN
bptjm-41	183	34	:	:	PUNCT
bptjm-41	183	35	serum	serum	NOUN
bptjm-41	183	36	levels	level	NOUN
bptjm-41	183	37	and	and	CCONJ
bptjm-41	183	38	hepatic	hepatic	ADJ
bptjm-41	183	39	messenger	messenger	NOUN
bptjm-41	183	40	ribonucleic	ribonucleic	ADJ
bptjm-41	183	41	acid	acid	NOUN
bptjm-41	183	42	responses	response	NOUN
bptjm-41	183	43	in	in	ADP
bptjm-41	183	44	humans1	humans1	PROPN
bptjm-41	183	45	.	.	PUNCT
bptjm-41	184	1	the	the	DET
bptjm-41	184	2	journal	journal	NOUN
bptjm-41	184	3	of	of	ADP
bptjm-41	184	4	clinical	clinical	ADJ
bptjm-41	184	5	endocrinology	endocrinology	NOUN
bptjm-41	184	6	&	&	CCONJ
bptjm-41	184	7	amp	amp	PROPN
bptjm-41	184	8	;	;	PUNCT
bptjm-41	184	9	metabolism	metabolism	NOUN
bptjm-41	184	10	.	.	PUNCT
bptjm-41	185	1	1999;84(2):553	1999;84(2):553	NUM
bptjm-41	185	2	-	-	SYM
bptjm-41	185	3	560	560	NUM
bptjm-41	185	4	.	.	PUNCT
bptjm-41	186	1	doi:10.1210	doi:10.1210	PROPN
bptjm-41	186	2	/	/	SYM
bptjm-41	186	3	jcem.84.2.5466	jcem.84.2.5466	PROPN
bptjm-41	186	4	26	26	NUM
bptjm-41	186	5	.	.	PUNCT
bptjm-41	187	1	hong	hong	PROPN
bptjm-41	187	2	s	s	PROPN
bptjm-41	187	3	,	,	PUNCT
bptjm-41	187	4	kim	kim	PROPN
bptjm-41	187	5	m	m	PROPN
bptjm-41	187	6	-	-	PUNCT
bptjm-41	187	7	m.	m.	NOUN
bptjm-41	187	8	igfbp-3	igfbp-3	PRON
bptjm-41	187	9	plays	play	VERB
bptjm-41	187	10	an	an	DET
bptjm-41	187	11	important	important	ADJ
bptjm-41	187	12	role	role	NOUN
bptjm-41	187	13	in	in	ADP
bptjm-41	187	14	senescence	senescence	NOUN
bptjm-41	187	15	as	as	ADP
bptjm-41	187	16	an	an	DET
bptjm-41	187	17	aging	age	VERB
bptjm-41	187	18	marker	marker	NOUN
bptjm-41	187	19	.	.	PUNCT
bptjm-41	188	1	environmental	environmental	ADJ
bptjm-41	188	2	toxicology	toxicology	NOUN
bptjm-41	188	3	and	and	CCONJ
bptjm-41	188	4	pharmacology	pharmacology	NOUN
bptjm-41	188	5	.	.	PUNCT
bptjm-41	189	1	2018;59:138	2018;59:138	PROPN
bptjm-41	189	2	-	-	SYM
bptjm-41	189	3	145	145	NUM
bptjm-41	189	4	.	.	PUNCT
bptjm-41	190	1	doi:10.1016	doi:10.1016	PROPN
bptjm-41	190	2	/	/	SYM
bptjm-41	190	3	j.etap.2018.03.014	j.etap.2018.03.014	PROPN
bptjm-41	190	4	27	27	NUM
bptjm-41	190	5	.	.	PUNCT
bptjm-41	191	1	hong	hong	PROPN
bptjm-41	191	2	s	s	PROPN
bptjm-41	191	3	,	,	PUNCT
bptjm-41	191	4	kim	kim	PROPN
bptjm-41	191	5	m	m	PROPN
bptjm-41	191	6	-	-	PUNCT
bptjm-41	191	7	m.	m.	NOUN
bptjm-41	191	8	igfbp-3	igfbp-3	PRON
bptjm-41	191	9	plays	play	VERB
bptjm-41	191	10	an	an	DET
bptjm-41	191	11	important	important	ADJ
bptjm-41	191	12	role	role	NOUN
bptjm-41	191	13	in	in	ADP
bptjm-41	191	14	senescence	senescence	NOUN
bptjm-41	191	15	as	as	ADP
bptjm-41	191	16	an	an	DET
bptjm-41	191	17	aging	age	VERB
bptjm-41	191	18	marker	marker	NOUN
bptjm-41	191	19	.	.	PUNCT
bptjm-41	192	1	environmental	environmental	ADJ
bptjm-41	192	2	toxicology	toxicology	NOUN
bptjm-41	192	3	and	and	CCONJ
bptjm-41	192	4	pharmacology	pharmacology	NOUN
bptjm-41	192	5	.	.	PUNCT
bptjm-41	193	1	2018;59:138	2018;59:138	PROPN
bptjm-41	193	2	-	-	SYM
bptjm-41	193	3	145	145	NUM
bptjm-41	193	4	.	.	PUNCT
bptjm-41	194	1	doi:10.1016	doi:10.1016	PROPN
bptjm-41	194	2	/	/	SYM
bptjm-41	194	3	j.etap.2018.03.014	j.etap.2018.03.014	PROPN
bptjm-41	194	4	28	28	NUM
bptjm-41	194	5	.	.	PUNCT
bptjm-41	195	1	yamada	yamada	PROPN
bptjm-41	195	2	pm	pm	PROPN
bptjm-41	195	3	,	,	PUNCT
bptjm-41	195	4	mehta	mehta	PROPN
bptjm-41	195	5	hh	hh	PROPN
bptjm-41	195	6	,	,	PUNCT
bptjm-41	195	7	hwang	hwang	PROPN
bptjm-41	195	8	d	d	PROPN
bptjm-41	195	9	,	,	PUNCT
bptjm-41	195	10	roos	roos	PROPN
bptjm-41	195	11	kp	kp	PROPN
bptjm-41	195	12	,	,	PUNCT
bptjm-41	195	13	hevener	hevener	PROPN
bptjm-41	195	14	al	al	PROPN
bptjm-41	195	15	,	,	PUNCT
bptjm-41	195	16	lee	lee	PROPN
bptjm-41	195	17	kw	kw	PROPN
bptjm-41	195	18	.	.	PUNCT
bptjm-41	196	1	evidence	evidence	NOUN
bptjm-41	196	2	of	of	ADP
bptjm-41	196	3	a	a	DET
bptjm-41	196	4	role	role	NOUN
bptjm-41	196	5	for	for	ADP
bptjm-41	196	6	insulin	insulin	NOUN
bptjm-41	196	7	-	-	PUNCT
bptjm-41	196	8	like	like	ADJ
bptjm-41	196	9	growth	growth	NOUN
bptjm-41	196	10	factor	factor	NOUN
bptjm-41	196	11	binding	bind	VERB
bptjm-41	196	12	protein	protein	NOUN
bptjm-41	196	13	(	(	PUNCT
bptjm-41	196	14	igfbp)-3	igfbp)-3	PROPN
bptjm-41	196	15	in	in	ADP
bptjm-41	196	16	metabolic	metabolic	NOUN
bptjm-41	196	17	regulation	regulation	NOUN
bptjm-41	196	18	.	.	PUNCT
bptjm-41	197	1	endocrinology	endocrinology	NOUN
bptjm-41	197	2	.	.	PUNCT
bptjm-41	198	1	2010;151(12):5741	2010;151(12):5741	X
bptjm-41	198	2	-	-	SYM
bptjm-41	198	3	5750	5750	NUM
bptjm-41	198	4	.	.	PUNCT
bptjm-41	199	1	doi:10.1210	doi:10.1210	PROPN
bptjm-41	199	2	/	/	SYM
bptjm-41	199	3	en.2010	en.2010	PROPN
bptjm-41	199	4	-	-	PUNCT
bptjm-41	199	5	0672	0672	NUM
bptjm-41	199	6	29	29	NUM
bptjm-41	199	7	.	.	PUNCT
bptjm-41	200	1	solomon	solomon	PROPN
bptjm-41	200	2	vr	vr	PROPN
bptjm-41	200	3	,	,	PUNCT
bptjm-41	200	4	lee	lee	PROPN
bptjm-41	200	5	h.	h.	PROPN
bptjm-41	200	6	chloroquine	chloroquine	PROPN
bptjm-41	200	7	and	and	CCONJ
bptjm-41	200	8	its	its	PRON
bptjm-41	200	9	analogs	analog	NOUN
bptjm-41	200	10	:	:	PUNCT
bptjm-41	200	11	a	a	DET
bptjm-41	200	12	new	new	ADJ
bptjm-41	200	13	promise	promise	NOUN
bptjm-41	200	14	of	of	ADP
bptjm-41	200	15	an	an	DET
bptjm-41	200	16	old	old	ADJ
bptjm-41	200	17	drug	drug	NOUN
bptjm-41	200	18	for	for	ADP
bptjm-41	200	19	e	e	NOUN
bptjm-41	200	20	�	�	NOUN
bptjm-41	200	21	ective	ective	ADJ
bptjm-41	200	22	and	and	CCONJ
bptjm-41	200	23	safe	safe	ADJ
bptjm-41	200	24	cancer	cancer	NOUN
bptjm-41	200	25	therapies	therapy	NOUN
bptjm-41	200	26	.	.	PUNCT
bptjm-41	201	1	european	european	PROPN
bptjm-41	201	2	journal	journal	PROPN
bptjm-41	201	3	of	of	ADP
bptjm-41	201	4	pharmacology	pharmacology	NOUN
bptjm-41	201	5	.	.	PUNCT
bptjm-41	202	1	2009;625(1	2009;625(1	X
bptjm-41	202	2	-	-	PUNCT
bptjm-41	202	3	3):220	3):220	NOUN
bptjm-41	202	4	-	-	PUNCT
bptjm-41	202	5	233	233	NUM
bptjm-41	202	6	.	.	PUNCT
bptjm-41	202	7	doi:10.1016	doi:10.1016	PROPN
bptjm-41	202	8	/	/	SYM
bptjm-41	202	9	j.ejphar.2009.06.063	j.ejphar.2009.06.063	PROPN
bptjm-41	202	10	30	30	NUM
bptjm-41	202	11	.	.	PUNCT
bptjm-41	203	1	qian	qian	PROPN
bptjm-41	203	2	m	m	PROPN
bptjm-41	203	3	,	,	PUNCT
bptjm-41	203	4	liu	liu	PROPN
bptjm-41	203	5	z	z	PROPN
bptjm-41	203	6	,	,	PUNCT
bptjm-41	203	7	peng	peng	PROPN
bptjm-41	203	8	l	l	PROPN
bptjm-41	203	9	,	,	PUNCT
bptjm-41	203	10	et	et	PROPN
bptjm-41	203	11	al	al	PROPN
bptjm-41	203	12	.	.	PUNCT
bptjm-41	204	1	boosting	boost	VERB
bptjm-41	204	2	atm	atm	NOUN
bptjm-41	204	3	activity	activity	NOUN
bptjm-41	204	4	alleviates	alleviate	VERB
bptjm-41	204	5	aging	age	VERB
bptjm-41	204	6	and	and	CCONJ
bptjm-41	204	7	extends	extend	VERB
bptjm-41	204	8	lifespan	lifespan	NOUN
bptjm-41	204	9	in	in	ADP
bptjm-41	204	10	a	a	DET
bptjm-41	204	11	mouse	mouse	NOUN
bptjm-41	204	12	model	model	NOUN
bptjm-41	204	13	of	of	ADP
bptjm-41	204	14	progeria	progeria	NOUN
bptjm-41	204	15	.	.	PUNCT
bptjm-41	205	1	elife	elife	NOUN
bptjm-41	205	2	.	.	PUNCT
bptjm-41	206	1	2018;7	2018;7	X
bptjm-41	206	2	.	.	PUNCT
bptjm-41	207	1	doi:10.7554	doi:10.7554	PROPN
bptjm-41	207	2	/	/	SYM
bptjm-41	208	1	elife.34836	elife.34836	PROPN
bptjm-41	208	2	31	31	NUM
bptjm-41	208	3	.	.	PUNCT
bptjm-41	208	4	emami	emami	PROPN
bptjm-41	208	5	j	j	PROPN
bptjm-41	208	6	,	,	PUNCT
bptjm-41	208	7	gerstein	gerstein	NOUN
bptjm-41	208	8	hc	hc	PROPN
bptjm-41	208	9	,	,	PUNCT
bptjm-41	208	10	pasutto	pasutto	PROPN
bptjm-41	208	11	fm	fm	PROPN
bptjm-41	208	12	,	,	PUNCT
bptjm-41	208	13	jamali	jamali	PROPN
bptjm-41	208	14	f.	f.	PROPN
bptjm-41	208	15	insulin	insulin	PROPN
bptjm-41	208	16	-	-	PUNCT
bptjm-41	208	17	sparing	spare	VERB
bptjm-41	208	18	e	e	NOUN
bptjm-41	208	19	�	�	NOUN
bptjm-41	208	20	ect	ect	NOUN
bptjm-41	208	21	of	of	ADP
bptjm-41	208	22	hydroxychloroquine	hydroxychloroquine	NOUN
bptjm-41	208	23	in	in	ADP
bptjm-41	208	24	diabetic	diabetic	ADJ
bptjm-41	208	25	rats	rat	NOUN
bptjm-41	208	26	is	be	AUX
bptjm-41	208	27	concentration	concentration	NOUN
bptjm-41	208	28	dependent	dependent	ADJ
bptjm-41	208	29	.	.	PUNCT
bptjm-41	209	1	canadian	canadian	ADJ
bptjm-41	209	2	journal	journal	PROPN
bptjm-41	209	3	of	of	ADP
bptjm-41	209	4	physiology	physiology	NOUN
bptjm-41	209	5	and	and	CCONJ
bptjm-41	209	6	pharmacology	pharmacology	NOUN
bptjm-41	209	7	.	.	PUNCT
bptjm-41	210	1	1999;77(2):118	1999;77(2):118	NUM
bptjm-41	210	2	-	-	SYM
bptjm-41	210	3	123	123	NUM
bptjm-41	210	4	.	.	PUNCT
bptjm-41	211	1	doi:10.1139	doi:10.1139	PROPN
bptjm-41	211	2	/	/	SYM
bptjm-41	211	3	y98	y98	PROPN
bptjm-41	211	4	-	-	SYM
bptjm-41	211	5	146	146	NUM
bptjm-41	211	6	32	32	NUM
bptjm-41	211	7	.	.	PUNCT
bptjm-41	212	1	schneider	schneider	PROPN
bptjm-41	212	2	jg	jg	PROPN
bptjm-41	212	3	,	,	PUNCT
bptjm-41	212	4	finck	finck	PROPN
bptjm-41	212	5	bn	bn	NOUN
bptjm-41	212	6	,	,	PUNCT
bptjm-41	212	7	ren	ren	PROPN
bptjm-41	212	8	j	j	PROPN
bptjm-41	212	9	,	,	PUNCT
bptjm-41	212	10	et	et	PROPN
bptjm-41	212	11	al	al	PROPN
bptjm-41	212	12	.	.	PUNCT
bptjm-41	213	1	atm	atm	ADJ
bptjm-41	213	2	-	-	PUNCT
bptjm-41	213	3	dependent	dependent	ADJ
bptjm-41	213	4	suppression	suppression	NOUN
bptjm-41	213	5	of	of	ADP
bptjm-41	213	6	stress	stress	NOUN
bptjm-41	213	7	signaling	signal	VERB
bptjm-41	213	8	reduces	reduce	VERB
bptjm-41	213	9	vascular	vascular	ADJ
bptjm-41	213	10	disease	disease	NOUN
bptjm-41	213	11	in	in	ADP
bptjm-41	213	12	metabolic	metabolic	NOUN
bptjm-41	213	13	syndrome	syndrome	NOUN
bptjm-41	213	14	.	.	PUNCT
bptjm-41	214	1	cell	cell	NOUN
bptjm-41	214	2	berkeley	berkeley	PROPN
bptjm-41	214	3	pharma	pharma	PROPN
bptjm-41	214	4	tech	tech	NOUN
bptjm-41	214	5	journal	journal	NOUN
bptjm-41	214	6	of	of	ADP
bptjm-41	214	7	medicine	medicine	NOUN
bptjm-41	214	8	|	|	ADV
bptjm-41	214	9	8	8	NUM
bptjm-41	214	10	metabolism	metabolism	NOUN
bptjm-41	214	11	.	.	PUNCT
bptjm-41	215	1	2006;4(5):377	2006;4(5):377	X
bptjm-41	215	2	-	-	SYM
bptjm-41	215	3	389	389	NUM
bptjm-41	215	4	.	.	PUNCT
bptjm-41	215	5	doi:10.1016	doi:10.1016	PROPN
bptjm-41	215	6	/	/	SYM
bptjm-41	215	7	j.cmet.2006.10.002	j.cmet.2006.10.002	PROPN
bptjm-41	215	8	33	33	NUM
bptjm-41	215	9	.	.	PUNCT
bptjm-41	216	1	razani	razani	PROPN
bptjm-41	216	2	b	b	PROPN
bptjm-41	216	3	,	,	PUNCT
bptjm-41	216	4	feng	feng	PROPN
bptjm-41	216	5	c	c	AUX
bptjm-41	216	6	,	,	PUNCT
bptjm-41	216	7	semenkovich	semenkovich	PROPN
bptjm-41	216	8	cf	cf	NOUN
bptjm-41	216	9	.	.	PUNCT
bptjm-41	217	1	p53	p53	NOUN
bptjm-41	217	2	is	be	AUX
bptjm-41	217	3	required	require	VERB
bptjm-41	217	4	for	for	ADP
bptjm-41	217	5	chloroquine	chloroquine	NOUN
bptjm-41	217	6	-	-	PUNCT
bptjm-41	217	7	induced	induce	VERB
bptjm-41	217	8	atheroprotection	atheroprotection	NOUN
bptjm-41	217	9	but	but	CCONJ
bptjm-41	217	10	not	not	PART
bptjm-41	217	11	insulin	insulin	NOUN
bptjm-41	217	12	sensitization	sensitization	NOUN
bptjm-41	217	13	.	.	PUNCT
bptjm-41	218	1	journal	journal	PROPN
bptjm-41	218	2	of	of	ADP
bptjm-41	218	3	lipid	lipid	PROPN
bptjm-41	218	4	research	research	NOUN
bptjm-41	218	5	.	.	PUNCT
bptjm-41	219	1	2010;51(7):1738	2010;51(7):1738	NUM
bptjm-41	219	2	-	-	SYM
bptjm-41	219	3	1746	1746	NUM
bptjm-41	219	4	.	.	PUNCT
bptjm-41	220	1	doi:10.1194	doi:10.1194	PROPN
bptjm-41	220	2	/	/	SYM
bptjm-41	220	3	jlr.m003681	jlr.m003681	PROPN
bptjm-41	220	4	34	34	NUM
bptjm-41	220	5	.	.	PUNCT
bptjm-41	221	1	lópez	lópez	NOUN
bptjm-41	221	2	-	-	PUNCT
bptjm-41	221	3	otín	otín	PROPN
bptjm-41	221	4	c	c	PROPN
bptjm-41	221	5	,	,	PUNCT
bptjm-41	221	6	blasco	blasco	PROPN
bptjm-41	221	7	ma	ma	PROPN
bptjm-41	221	8	,	,	PUNCT
bptjm-41	221	9	partridge	partridge	NOUN
bptjm-41	221	10	l	l	PROPN
bptjm-41	221	11	,	,	PUNCT
bptjm-41	221	12	serrano	serrano	PROPN
bptjm-41	221	13	m	m	PROPN
bptjm-41	221	14	,	,	PUNCT
bptjm-41	221	15	kroemer	kroemer	PROPN
bptjm-41	221	16	g.	g.	PROPN
bptjm-41	222	1	the	the	DET
bptjm-41	222	2	hallmarks	hallmark	NOUN
bptjm-41	222	3	of	of	ADP
bptjm-41	222	4	aging	aging	NOUN
bptjm-41	222	5	.	.	PUNCT
bptjm-41	223	1	cell	cell	NOUN
bptjm-41	223	2	.	.	PUNCT
bptjm-41	224	1	2013;153(6):1194	2013;153(6):1194	NUM
bptjm-41	224	2	-	-	SYM
bptjm-41	224	3	1217	1217	NUM
bptjm-41	224	4	.	.	PUNCT
bptjm-41	225	1	doi:10.1016	doi:10.1016	PROPN
bptjm-41	225	2	/	/	SYM
bptjm-41	225	3	j.cell.2013.05.039	j.cell.2013.05.039	PROPN
bptjm-41	225	4	35	35	NUM
bptjm-41	225	5	.	.	PUNCT
bptjm-41	226	1	maes	maes	PROPN
bptjm-41	226	2	h	h	PROPN
bptjm-41	226	3	,	,	PUNCT
bptjm-41	226	4	kuchnio	kuchnio	X
bptjm-41	226	5	a	a	PRON
bptjm-41	226	6	,	,	PUNCT
bptjm-41	226	7	peric	peric	NOUN
bptjm-41	226	8	a	a	X
bptjm-41	226	9	,	,	PUNCT
bptjm-41	226	10	et	et	PROPN
bptjm-41	226	11	al	al	PROPN
bptjm-41	226	12	.	.	PROPN
bptjm-41	226	13	tumor	tumor	PROPN
bptjm-41	226	14	vessel	vessel	NOUN
bptjm-41	226	15	normalization	normalization	NOUN
bptjm-41	226	16	by	by	ADP
bptjm-41	226	17	chloroquine	chloroquine	PROPN
bptjm-41	226	18	independent	independent	NOUN
bptjm-41	226	19	of	of	ADP
bptjm-41	226	20	autophagy	autophagy	NOUN
bptjm-41	226	21	.	.	PUNCT
bptjm-41	227	1	cancer	cancer	NOUN
bptjm-41	227	2	cell	cell	NOUN
bptjm-41	227	3	.	.	PUNCT
bptjm-41	228	1	2014;26(2):190	2014;26(2):190	NUM
bptjm-41	228	2	-	-	PUNCT
bptjm-41	228	3	206	206	NUM
bptjm-41	228	4	.	.	PUNCT
bptjm-41	229	1	doi:10.1016	doi:10.1016	PROPN
bptjm-41	229	2	/	/	SYM
bptjm-41	229	3	j.ccr.2014.06.025	j.ccr.2014.06.025	PROPN
bptjm-41	229	4	36	36	NUM
bptjm-41	229	5	.	.	PUNCT
bptjm-41	230	1	he	he	PRON
bptjm-41	230	2	w	w	PROPN
bptjm-41	230	3	,	,	PUNCT
bptjm-41	230	4	wang	wang	PROPN
bptjm-41	230	5	b	b	PROPN
bptjm-41	230	6	,	,	PUNCT
bptjm-41	230	7	yang	yang	PROPN
bptjm-41	230	8	j	j	PROPN
bptjm-41	230	9	,	,	PUNCT
bptjm-41	231	1	et	et	PROPN
bptjm-41	231	2	al	al	PROPN
bptjm-41	231	3	.	.	PROPN
bptjm-41	231	4	chloroquine	chloroquine	PROPN
bptjm-41	231	5	improved	improve	VERB
bptjm-41	231	6	carbon	carbon	NOUN
bptjm-41	231	7	tetrachloride	tetrachloride	NOUN
bptjm-41	231	8	-	-	PUNCT
bptjm-41	231	9	induced	induce	VERB
bptjm-41	231	10	liver	liver	NOUN
bptjm-41	231	11	�	�	NOUN
bptjm-41	231	12	brosis	brosi	VERB
bptjm-41	231	13	through	through	ADP
bptjm-41	231	14	its	its	PRON
bptjm-41	231	15	inhibition	inhibition	NOUN
bptjm-41	231	16	of	of	ADP
bptjm-41	231	17	the	the	DET
bptjm-41	231	18	activation	activation	NOUN
bptjm-41	231	19	of	of	ADP
bptjm-41	231	20	hepatic	hepatic	ADJ
bptjm-41	231	21	stellate	stellate	ADJ
bptjm-41	231	22	cells	cell	NOUN
bptjm-41	231	23	:	:	PUNCT
bptjm-41	231	24	role	role	NOUN
bptjm-41	231	25	of	of	ADP
bptjm-41	231	26	autophagy	autophagy	NOUN
bptjm-41	231	27	.	.	PUNCT
bptjm-41	232	1	biological	biological	ADJ
bptjm-41	232	2	and	and	CCONJ
bptjm-41	232	3	pharmaceutical	pharmaceutical	ADJ
bptjm-41	232	4	bulletin	bulletin	NOUN
bptjm-41	232	5	.	.	PUNCT
bptjm-41	233	1	2014;37(9):1505	2014;37(9):1505	PROPN
bptjm-41	233	2	-	-	PUNCT
bptjm-41	233	3	1509	1509	NUM
bptjm-41	233	4	.	.	PUNCT
bptjm-41	234	1	doi:10.1248	doi:10.1248	ADJ
bptjm-41	234	2	/	/	SYM
bptjm-41	234	3	bpb.b14	bpb.b14	PROPN
bptjm-41	234	4	-	-	PUNCT
bptjm-41	234	5	00297	00297	NUM
bptjm-41	234	6	37	37	NUM
bptjm-41	234	7	.	.	PUNCT
bptjm-41	235	1	shen	shen	PROPN
bptjm-41	235	2	h	h	PROPN
bptjm-41	235	3	,	,	PUNCT
bptjm-41	235	4	wu	wu	PROPN
bptjm-41	235	5	n	n	CCONJ
bptjm-41	235	6	,	,	PUNCT
bptjm-41	235	7	wang	wang	PROPN
bptjm-41	235	8	y	y	PROPN
bptjm-41	235	9	,	,	PUNCT
bptjm-41	235	10	et	et	PROPN
bptjm-41	235	11	al	al	PROPN
bptjm-41	235	12	.	.	PUNCT
bptjm-41	236	1	chloroquine	chloroquine	PROPN
bptjm-41	236	2	attenuates	attenuate	VERB
bptjm-41	236	3	paraquat	paraquat	NOUN
bptjm-41	236	4	-	-	PUNCT
bptjm-41	236	5	induced	induce	VERB
bptjm-41	236	6	lung	lung	NOUN
bptjm-41	236	7	injury	injury	NOUN
bptjm-41	236	8	in	in	ADP
bptjm-41	236	9	mice	mouse	NOUN
bptjm-41	236	10	by	by	ADP
bptjm-41	236	11	altering	alter	VERB
bptjm-41	236	12	in	in	ADP
bptjm-41	236	13	�	�	PROPN
bptjm-41	236	14	ammation	ammation	NOUN
bptjm-41	236	15	,	,	PUNCT
bptjm-41	236	16	oxidative	oxidative	ADJ
bptjm-41	236	17	stress	stress	NOUN
bptjm-41	236	18	and	and	CCONJ
bptjm-41	236	19	�	�	NOUN
bptjm-41	236	20	brosis	brosis	NOUN
bptjm-41	236	21	.	.	PUNCT
bptjm-41	237	1	international	international	ADJ
bptjm-41	237	2	immunopharmacology	immunopharmacology	NOUN
bptjm-41	237	3	.	.	PUNCT
bptjm-41	238	1	2017;46:16	2017;46:16	NUM
bptjm-41	238	2	-	-	SYM
bptjm-41	238	3	22	22	NUM
bptjm-41	238	4	.	.	PUNCT
bptjm-41	239	1	doi:10.1016	doi:10.1016	PROPN
bptjm-41	239	2	/	/	SYM
bptjm-41	239	3	j.intimp.2017.02.020	j.intimp.2017.02.020	PROPN
bptjm-41	239	4	38	38	NUM
bptjm-41	239	5	.	.	PUNCT
bptjm-41	240	1	schrezenmeier	schrezenmeier	PROPN
bptjm-41	240	2	e	e	NOUN
bptjm-41	240	3	,	,	PUNCT
bptjm-41	240	4	dörner	dörner	NOUN
bptjm-41	240	5	t.	t.	NOUN
bptjm-41	240	6	mechanisms	mechanism	NOUN
bptjm-41	240	7	of	of	ADP
bptjm-41	240	8	action	action	NOUN
bptjm-41	240	9	of	of	ADP
bptjm-41	240	10	hydroxychloroquine	hydroxychloroquine	NOUN
bptjm-41	240	11	and	and	CCONJ
bptjm-41	240	12	chloroquine	chloroquine	NOUN
bptjm-41	240	13	:	:	PUNCT
bptjm-41	240	14	implications	implication	NOUN
bptjm-41	240	15	for	for	ADP
bptjm-41	240	16	rheumatology	rheumatology	NOUN
bptjm-41	240	17	.	.	PUNCT
bptjm-41	241	1	nature	nature	NOUN
bptjm-41	241	2	reviews	review	VERB
bptjm-41	241	3	rheumatology	rheumatology	NOUN
bptjm-41	241	4	.	.	PUNCT
bptjm-41	242	1	2020;16(3):155	2020;16(3):155	NUM
bptjm-41	242	2	-	-	SYM
bptjm-41	242	3	166	166	NUM
bptjm-41	242	4	.	.	PUNCT
bptjm-41	242	5	doi:10.1038	doi:10.1038	NOUN
bptjm-41	242	6	/	/	SYM
bptjm-41	242	7	s41584	s41584	NOUN
bptjm-41	242	8	-	-	PUNCT
bptjm-41	242	9	020	020	NUM
bptjm-41	242	10	-	-	PUNCT
bptjm-41	242	11	0372	0372	NUM
bptjm-41	242	12	-	-	PUNCT
bptjm-41	242	13	x	x	SYM
bptjm-41	242	14	39	39	NUM
bptjm-41	242	15	.	.	PUNCT
bptjm-41	243	1	longo	longo	PROPN
bptjm-41	243	2	vd	vd	NOUN
bptjm-41	243	3	,	,	PUNCT
bptjm-41	243	4	antebi	antebi	VERB
bptjm-41	243	5	a	a	PRON
bptjm-41	243	6	,	,	PUNCT
bptjm-41	243	7	bartke	bartke	NOUN
bptjm-41	243	8	a	a	PRON
bptjm-41	243	9	,	,	PUNCT
bptjm-41	243	10	et	et	PROPN
bptjm-41	243	11	al	al	PROPN
bptjm-41	243	12	.	.	PROPN
bptjm-41	244	1	interventions	intervention	NOUN
bptjm-41	244	2	to	to	PART
bptjm-41	244	3	slow	slow	VERB
bptjm-41	244	4	aging	aging	NOUN
bptjm-41	244	5	in	in	ADP
bptjm-41	244	6	humans	human	NOUN
bptjm-41	244	7	:	:	PUNCT
bptjm-41	244	8	are	be	AUX
bptjm-41	244	9	we	we	PRON
bptjm-41	244	10	ready	ready	ADJ
bptjm-41	244	11	?	?	PUNCT
bptjm-41	244	12	.	.	PUNCT
bptjm-41	245	1	aging	age	VERB
bptjm-41	245	2	cell	cell	NOUN
bptjm-41	245	3	.	.	PUNCT
bptjm-41	246	1	2015;14(4):497	2015;14(4):497	NUM
bptjm-41	246	2	-	-	SYM
bptjm-41	246	3	510	510	NUM
bptjm-41	246	4	.	.	PUNCT
bptjm-41	247	1	doi:10.1111	doi:10.1111	ADJ
bptjm-41	247	2	/	/	SYM
bptjm-41	247	3	acel.12338	acel.12338	PROPN
bptjm-41	247	4	40	40	NUM
bptjm-41	247	5	.	.	PUNCT
bptjm-41	248	1	wozniacka	wozniacka	PROPN
bptjm-41	248	2	a	a	PRON
bptjm-41	248	3	,	,	PUNCT
bptjm-41	248	4	cygankiewicz	cygankiewicz	NOUN
bptjm-41	248	5	i	i	PRON
bptjm-41	248	6	,	,	PUNCT
bptjm-41	248	7	chudzik	chudzik	PROPN
bptjm-41	248	8	m	m	NOUN
bptjm-41	248	9	,	,	PUNCT
bptjm-41	248	10	sysa	sysa	NOUN
bptjm-41	248	11	-	-	PUNCT
bptjm-41	248	12	jędrzejowska	jędrzejowska	PROPN
bptjm-41	248	13	a	a	PRON
bptjm-41	248	14	,	,	PUNCT
bptjm-41	248	15	wranicz	wranicz	PROPN
bptjm-41	248	16	jk	jk	PROPN
bptjm-41	248	17	.	.	PUNCT
bptjm-41	249	1	the	the	DET
bptjm-41	249	2	cardiac	cardiac	ADJ
bptjm-41	249	3	safety	safety	NOUN
bptjm-41	249	4	of	of	ADP
bptjm-41	249	5	chloroquine	chloroquine	ADJ
bptjm-41	249	6	phosphate	phosphate	NOUN
bptjm-41	249	7	treatment	treatment	NOUN
bptjm-41	249	8	in	in	ADP
bptjm-41	249	9	patients	patient	NOUN
bptjm-41	249	10	with	with	ADP
bptjm-41	249	11	systemic	systemic	ADJ
bptjm-41	249	12	lupus	lupus	PROPN
bptjm-41	249	13	erythematosus	erythematosus	NOUN
bptjm-41	249	14	:	:	PUNCT
bptjm-41	249	15	the	the	PRON
bptjm-41	249	16	in	in	ADP
bptjm-41	249	17	�	�	NOUN
bptjm-41	249	18	uence	uence	NOUN
bptjm-41	249	19	on	on	ADP
bptjm-41	249	20	arrhythmia	arrhythmia	NOUN
bptjm-41	249	21	,	,	PUNCT
bptjm-41	249	22	heart	heart	NOUN
bptjm-41	249	23	rate	rate	NOUN
bptjm-41	249	24	variability	variability	NOUN
bptjm-41	249	25	and	and	CCONJ
bptjm-41	249	26	repolarization	repolarization	NOUN
bptjm-41	249	27	parameters	parameter	NOUN
bptjm-41	249	28	.	.	PUNCT
bptjm-41	250	1	lupus	lupus	NOUN
bptjm-41	250	2	.	.	PUNCT
bptjm-41	251	1	2006;15(8):521	2006;15(8):521	NUM
bptjm-41	251	2	-	-	SYM
bptjm-41	251	3	525	525	NUM
bptjm-41	251	4	.	.	PUNCT
bptjm-41	252	1	doi:10.1191/0961203306lu2345oa	doi:10.1191/0961203306lu2345oa	PROPN
bptjm-41	252	2	berkeley	berkeley	PROPN
bptjm-41	252	3	pharma	pharma	PROPN
bptjm-41	252	4	tech	tech	NOUN
bptjm-41	252	5	journal	journal	NOUN
bptjm-41	252	6	of	of	ADP
bptjm-41	252	7	medicine	medicine	NOUN
bptjm-41	252	8	|	|	ADV
bptjm-41	252	9	9	9	NUM