id	sid	tid	token	lemma	pos
bptjm-66	1	1	chang	chang	PROPN
bptjm-66	1	2	references	reference	VERB
bptjm-66	1	3	berkeley	berkeley	PROPN
bptjm-66	1	4	pharma	pharma	PROPN
bptjm-66	1	5	tech	tech	NOUN
bptjm-66	1	6	journal	journal	NOUN
bptjm-66	1	7	of	of	ADP
bptjm-66	1	8	medicine	medicine	NOUN
bptjm-66	1	9	correspondence	correspondence	NOUN
bptjm-66	1	10	:	:	PUNCT
bptjm-66	1	11	bchang092@gmail.com	bchang092@gmail.com	X
bptjm-66	2	1	keywords	keyword	NOUN
bptjm-66	2	2	:	:	PUNCT
bptjm-66	2	3	pharmaceutical	pharmaceutical	ADJ
bptjm-66	2	4	non	non	ADJ
bptjm-66	2	5	-	-	ADJ
bptjm-66	2	6	pharmaceutical	pharmaceutical	ADJ
bptjm-66	2	7	medicine	medicine	NOUN
bptjm-66	2	8	pain	pain	NOUN
bptjm-66	2	9	nanotechnology	nanotechnology	PROPN
bptjm-66	2	10	published	publish	VERB
bptjm-66	2	11	july	july	PROPN
bptjm-66	2	12	31	31	NUM
bptjm-66	2	13	,	,	PUNCT
bptjm-66	2	14	2025	2025	NUM
bptjm-66	2	15	full	full	ADJ
bptjm-66	2	16	open	open	ADJ
bptjm-66	2	17	access	access	NOUN
bptjm-66	2	18	creative	creative	ADJ
bptjm-66	2	19	commons	common	NOUN
bptjm-66	2	20	attribution	attribution	NOUN
bptjm-66	2	21	license	license	VERB
bptjm-66	2	22	4.0	4.0	NUM
bptjm-66	2	23	abstract	abstract	ADJ
bptjm-66	2	24	pain	pain	NOUN
bptjm-66	2	25	medicine	medicine	NOUN
bptjm-66	2	26	has	have	AUX
bptjm-66	2	27	demonstrated	demonstrate	VERB
bptjm-66	2	28	its	its	PRON
bptjm-66	2	29	significance	significance	NOUN
bptjm-66	2	30	from	from	ADP
bptjm-66	2	31	brief	brief	ADJ
bptjm-66	2	32	surgical	surgical	ADJ
bptjm-66	2	33	procedures	procedure	NOUN
bptjm-66	2	34	to	to	ADP
bptjm-66	2	35	managing	manage	VERB
bptjm-66	2	36	chronic	chronic	ADJ
bptjm-66	2	37	illnesses	illness	NOUN
bptjm-66	2	38	.	.	PUNCT
bptjm-66	3	1	historically	historically	ADV
bptjm-66	3	2	,	,	PUNCT
bptjm-66	3	3	a	a	DET
bptjm-66	3	4	range	range	NOUN
bptjm-66	3	5	of	of	ADP
bptjm-66	3	6	analgesic	analgesic	ADJ
bptjm-66	3	7	and	and	CCONJ
bptjm-66	3	8	opioid	opioid	ADJ
bptjm-66	3	9	agents	agent	NOUN
bptjm-66	3	10	have	have	AUX
bptjm-66	3	11	been	be	AUX
bptjm-66	3	12	utilized	utilize	VERB
bptjm-66	3	13	as	as	ADP
bptjm-66	3	14	treatment	treatment	NOUN
bptjm-66	3	15	options	option	NOUN
bptjm-66	3	16	,	,	PUNCT
bptjm-66	3	17	and	and	CCONJ
bptjm-66	3	18	although	although	SCONJ
bptjm-66	3	19	effective	effective	ADJ
bptjm-66	3	20	to	to	ADP
bptjm-66	3	21	a	a	DET
bptjm-66	3	22	certain	certain	ADJ
bptjm-66	3	23	extent	extent	NOUN
bptjm-66	3	24	,	,	PUNCT
bptjm-66	3	25	traditional	traditional	ADJ
bptjm-66	3	26	approaches	approach	NOUN
bptjm-66	3	27	exhibit	exhibit	VERB
bptjm-66	3	28	limitations	limitation	NOUN
bptjm-66	3	29	.	.	PUNCT
bptjm-66	4	1	restricted	restrict	VERB
bptjm-66	4	2	by	by	ADP
bptjm-66	4	3	the	the	DET
bptjm-66	4	4	constraints	constraint	NOUN
bptjm-66	4	5	of	of	ADP
bptjm-66	4	6	technology	technology	NOUN
bptjm-66	4	7	,	,	PUNCT
bptjm-66	4	8	current	current	ADJ
bptjm-66	4	9	approaches	approach	NOUN
bptjm-66	4	10	fall	fall	VERB
bptjm-66	4	11	short	short	ADJ
bptjm-66	4	12	in	in	ADP
bptjm-66	4	13	specificity	specificity	NOUN
bptjm-66	4	14	and	and	CCONJ
bptjm-66	4	15	unintended	unintended	ADJ
bptjm-66	4	16	effects	effect	NOUN
bptjm-66	4	17	.	.	PUNCT
bptjm-66	5	1	this	this	DET
bptjm-66	5	2	review	review	NOUN
bptjm-66	5	3	article	article	NOUN
bptjm-66	5	4	delves	delve	VERB
bptjm-66	5	5	into	into	ADP
bptjm-66	5	6	the	the	DET
bptjm-66	5	7	evolving	evolve	VERB
bptjm-66	5	8	landscape	landscape	NOUN
bptjm-66	5	9	of	of	ADP
bptjm-66	5	10	pain	pain	NOUN
bptjm-66	5	11	management	management	NOUN
bptjm-66	5	12	,	,	PUNCT
bptjm-66	5	13	focusing	focus	VERB
bptjm-66	5	14	on	on	ADP
bptjm-66	5	15	emerging	emerge	VERB
bptjm-66	5	16	treatment	treatment	NOUN
bptjm-66	5	17	modalities	modality	NOUN
bptjm-66	5	18	within	within	ADP
bptjm-66	5	19	and	and	CCONJ
bptjm-66	5	20	beyond	beyond	ADP
bptjm-66	5	21	the	the	DET
bptjm-66	5	22	pharmaceutical	pharmaceutical	NOUN
bptjm-66	5	23	setting	setting	NOUN
bptjm-66	5	24	.	.	PUNCT
bptjm-66	6	1	non	non	ADJ
bptjm-66	6	2	-	-	ADJ
bptjm-66	6	3	pharmaceutical	pharmaceutical	ADJ
bptjm-66	6	4	treatment	treatment	NOUN
bptjm-66	6	5	modalities	modality	NOUN
bptjm-66	6	6	,	,	PUNCT
bptjm-66	6	7	including	include	VERB
bptjm-66	6	8	myofascial	myofascial	ADJ
bptjm-66	6	9	release	release	NOUN
bptjm-66	6	10	,	,	PUNCT
bptjm-66	6	11	transcutaneous	transcutaneous	ADJ
bptjm-66	6	12	electrical	electrical	ADJ
bptjm-66	6	13	nerve	nerve	NOUN
bptjm-66	6	14	stimulation	stimulation	NOUN
bptjm-66	6	15	(	(	PUNCT
bptjm-66	6	16	tens	ten	NOUN
bptjm-66	6	17	)	)	PUNCT
bptjm-66	6	18	,	,	PUNCT
bptjm-66	6	19	photobiomodulation	photobiomodulation	NOUN
bptjm-66	6	20	,	,	PUNCT
bptjm-66	6	21	and	and	CCONJ
bptjm-66	6	22	passive	passive	ADJ
bptjm-66	6	23	treatment	treatment	NOUN
bptjm-66	6	24	,	,	PUNCT
bptjm-66	6	25	such	such	ADJ
bptjm-66	6	26	as	as	ADP
bptjm-66	6	27	capsaicin	capsaicin	NOUN
bptjm-66	6	28	patches	patch	NOUN
bptjm-66	6	29	,	,	PUNCT
bptjm-66	6	30	introduce	introduce	VERB
bptjm-66	6	31	promising	promising	ADJ
bptjm-66	6	32	,	,	PUNCT
bptjm-66	6	33	non	non	ADJ
bptjm-66	6	34	-	-	ADJ
bptjm-66	6	35	invasive	invasive	ADJ
bptjm-66	6	36	treatment	treatment	NOUN
bptjm-66	6	37	options	option	NOUN
bptjm-66	6	38	for	for	ADP
bptjm-66	6	39	those	those	PRON
bptjm-66	6	40	experiencing	experience	VERB
bptjm-66	6	41	chronic	chronic	ADJ
bptjm-66	6	42	pain	pain	NOUN
bptjm-66	6	43	.	.	PUNCT
bptjm-66	7	1	the	the	DET
bptjm-66	7	2	advent	advent	NOUN
bptjm-66	7	3	of	of	ADP
bptjm-66	7	4	nanotechnology	nanotechnology	NOUN
bptjm-66	7	5	has	have	AUX
bptjm-66	7	6	also	also	ADV
bptjm-66	7	7	introduced	introduce	VERB
bptjm-66	7	8	an	an	DET
bptjm-66	7	9	exciting	exciting	ADJ
bptjm-66	7	10	new	new	ADJ
bptjm-66	7	11	avenue	avenue	NOUN
bptjm-66	7	12	that	that	PRON
bptjm-66	7	13	may	may	AUX
bptjm-66	7	14	herald	herald	VERB
bptjm-66	7	15	a	a	DET
bptjm-66	7	16	new	new	ADJ
bptjm-66	7	17	era	era	NOUN
bptjm-66	7	18	in	in	ADP
bptjm-66	7	19	personalized	personalized	ADJ
bptjm-66	7	20	medicine	medicine	NOUN
bptjm-66	7	21	.	.	PUNCT
bptjm-66	8	1	with	with	ADP
bptjm-66	8	2	many	many	ADJ
bptjm-66	8	3	promising	promising	ADJ
bptjm-66	8	4	treatment	treatment	NOUN
bptjm-66	8	5	modalities	modality	NOUN
bptjm-66	8	6	currently	currently	ADV
bptjm-66	8	7	under	under	ADP
bptjm-66	8	8	investigation	investigation	NOUN
bptjm-66	8	9	,	,	PUNCT
bptjm-66	8	10	this	this	DET
bptjm-66	8	11	review	review	NOUN
bptjm-66	8	12	article	article	NOUN
bptjm-66	8	13	aims	aim	VERB
bptjm-66	8	14	to	to	PART
bptjm-66	8	15	examine	examine	VERB
bptjm-66	8	16	and	and	CCONJ
bptjm-66	8	17	highlight	highlight	VERB
bptjm-66	8	18	the	the	DET
bptjm-66	8	19	advancements	advancement	NOUN
bptjm-66	8	20	in	in	ADP
bptjm-66	8	21	pain	pain	NOUN
bptjm-66	8	22	medicine	medicine	NOUN
bptjm-66	8	23	.	.	PUNCT
bptjm-66	9	1	it	it	PRON
bptjm-66	9	2	is	be	AUX
bptjm-66	9	3	imperative	imperative	ADJ
bptjm-66	9	4	to	to	PART
bptjm-66	9	5	understand	understand	VERB
bptjm-66	9	6	the	the	DET
bptjm-66	9	7	potential	potential	ADJ
bptjm-66	9	8	remedies	remedy	NOUN
bptjm-66	9	9	these	these	DET
bptjm-66	9	10	novel	novel	ADJ
bptjm-66	9	11	modalities	modality	NOUN
bptjm-66	9	12	may	may	AUX
bptjm-66	9	13	have	have	VERB
bptjm-66	9	14	in	in	ADP
bptjm-66	9	15	a	a	DET
bptjm-66	9	16	multitude	multitude	NOUN
bptjm-66	9	17	of	of	ADP
bptjm-66	9	18	neurodegenerative	neurodegenerative	ADJ
bptjm-66	9	19	disorders	disorder	NOUN
bptjm-66	9	20	,	,	PUNCT
bptjm-66	9	21	cancer	cancer	NOUN
bptjm-66	9	22	,	,	PUNCT
bptjm-66	9	23	and	and	CCONJ
bptjm-66	9	24	other	other	ADJ
bptjm-66	9	25	diseases	disease	NOUN
bptjm-66	9	26	.	.	PUNCT
bptjm-66	10	1	innovations	innovation	NOUN
bptjm-66	10	2	in	in	ADP
bptjm-66	10	3	pain	pain	NOUN
bptjm-66	10	4	management	management	NOUN
bptjm-66	10	5	:	:	PUNCT
bptjm-66	10	6	from	from	ADP
bptjm-66	10	7	traditional	traditional	ADJ
bptjm-66	10	8	analgesics	analgesic	NOUN
bptjm-66	10	9	to	to	PART
bptjm-66	10	10	novel	novel	VERB
bptjm-66	10	11	therapeutic	therapeutic	ADJ
bptjm-66	10	12	modalities	modality	NOUN
bptjm-66	10	13	by	by	ADP
bptjm-66	10	14	:	:	PUNCT
bptjm-66	10	15	brandon	brandon	PROPN
bptjm-66	10	16	chang	chang	PROPN
bptjm-66	10	17	,	,	PUNCT
bptjm-66	10	18	danica	danica	PROPN
bptjm-66	10	19	hergenroeder	hergenroeder	PROPN
bptjm-66	10	20	,	,	PUNCT
bptjm-66	10	21	glory	glory	NOUN
bptjm-66	10	22	gage	gage	NOUN
bptjm-66	10	23	and	and	CCONJ
bptjm-66	10	24	nathan	nathan	PROPN
bptjm-66	10	25	tan	tan	PROPN
bptjm-66	10	26	1	1	NUM
bptjm-66	10	27	.	.	PUNCT
bptjm-66	11	1	introduction	introduction	NOUN
bptjm-66	11	2	pain	pain	NOUN
bptjm-66	11	3	serves	serve	VERB
bptjm-66	11	4	as	as	ADP
bptjm-66	11	5	the	the	DET
bptjm-66	11	6	body	body	NOUN
bptjm-66	11	7	's	's	PART
bptjm-66	11	8	protective	protective	ADJ
bptjm-66	11	9	response	response	NOUN
bptjm-66	11	10	to	to	ADP
bptjm-66	11	11	external	external	ADJ
bptjm-66	11	12	stimuli	stimulus	NOUN
bptjm-66	11	13	that	that	PRON
bptjm-66	11	14	pose	pose	VERB
bptjm-66	11	15	potential	potential	ADJ
bptjm-66	11	16	harm	harm	NOUN
bptjm-66	11	17	.	.	PUNCT
bptjm-66	12	1	while	while	SCONJ
bptjm-66	12	2	essential	essential	ADJ
bptjm-66	12	3	for	for	ADP
bptjm-66	12	4	signaling	signal	VERB
bptjm-66	12	5	bodily	bodily	ADJ
bptjm-66	12	6	distress	distress	NOUN
bptjm-66	12	7	,	,	PUNCT
bptjm-66	12	8	persistent	persistent	ADJ
bptjm-66	12	9	or	or	CCONJ
bptjm-66	12	10	chronic	chronic	ADJ
bptjm-66	12	11	pain	pain	NOUN
bptjm-66	12	12	can	can	AUX
bptjm-66	12	13	persist	persist	VERB
bptjm-66	12	14	even	even	ADV
bptjm-66	12	15	after	after	SCONJ
bptjm-66	12	16	the	the	DET
bptjm-66	12	17	underlying	underlying	ADJ
bptjm-66	12	18	issues	issue	NOUN
bptjm-66	12	19	have	have	AUX
bptjm-66	12	20	been	be	AUX
bptjm-66	12	21	resolved	resolve	VERB
bptjm-66	12	22	,	,	PUNCT
bptjm-66	12	23	significantly	significantly	ADV
bptjm-66	12	24	hindering	hinder	VERB
bptjm-66	12	25	the	the	DET
bptjm-66	12	26	quality	quality	NOUN
bptjm-66	12	27	of	of	ADP
bptjm-66	12	28	life	life	NOUN
bptjm-66	12	29	for	for	ADP
bptjm-66	12	30	those	those	PRON
bptjm-66	12	31	affected	affect	VERB
bptjm-66	12	32	.	.	PUNCT
bptjm-66	13	1	1.1	1.1	NUM
bptjm-66	13	2	pathways	pathway	NOUN
bptjm-66	13	3	of	of	ADP
bptjm-66	13	4	pain	pain	NOUN
bptjm-66	13	5	pain	pain	NOUN
bptjm-66	13	6	can	can	AUX
bptjm-66	13	7	be	be	AUX
bptjm-66	13	8	classified	classify	VERB
bptjm-66	13	9	as	as	ADP
bptjm-66	13	10	either	either	CCONJ
bptjm-66	13	11	chronic	chronic	ADJ
bptjm-66	13	12	(	(	PUNCT
bptjm-66	13	13	long	long	ADJ
bptjm-66	13	14	-	-	PUNCT
bptjm-66	13	15	term	term	NOUN
bptjm-66	13	16	)	)	PUNCT
bptjm-66	13	17	or	or	CCONJ
bptjm-66	13	18	acute	acute	ADJ
bptjm-66	13	19	pain	pain	NOUN
bptjm-66	13	20	(	(	PUNCT
bptjm-66	13	21	short	short	ADJ
bptjm-66	13	22	-	-	PUNCT
bptjm-66	13	23	term	term	NOUN
bptjm-66	13	24	)	)	PUNCT
bptjm-66	13	25	.	.	PUNCT
bptjm-66	14	1	the	the	DET
bptjm-66	14	2	fundamental	fundamental	ADJ
bptjm-66	14	3	mechanisms	mechanism	NOUN
bptjm-66	14	4	causing	cause	VERB
bptjm-66	14	5	this	this	DET
bptjm-66	14	6	pain	pain	NOUN
bptjm-66	14	7	can	can	AUX
bptjm-66	14	8	be	be	AUX
bptjm-66	14	9	categorized	categorize	VERB
bptjm-66	14	10	into	into	ADP
bptjm-66	14	11	two	two	NUM
bptjm-66	14	12	main	main	ADJ
bptjm-66	14	13	groups	group	NOUN
bptjm-66	14	14	:	:	PUNCT
bptjm-66	14	15	nociceptive	nociceptive	ADJ
bptjm-66	14	16	and	and	CCONJ
bptjm-66	14	17	neuropathic	neuropathic	ADJ
bptjm-66	14	18	pain1	pain1	NOUN
bptjm-66	14	19	.	.	PUNCT
bptjm-66	15	1	nociceptive	nociceptive	ADJ
bptjm-66	15	2	pain	pain	NOUN
bptjm-66	15	3	is	be	AUX
bptjm-66	15	4	caused	cause	VERB
bptjm-66	15	5	by	by	ADP
bptjm-66	15	6	the	the	DET
bptjm-66	15	7	activation	activation	NOUN
bptjm-66	15	8	of	of	ADP
bptjm-66	15	9	nociceptors	nociceptor	NOUN
bptjm-66	15	10	in	in	ADP
bptjm-66	15	11	response	response	NOUN
bptjm-66	15	12	to	to	ADP
bptjm-66	15	13	surface	surface	NOUN
bptjm-66	15	14	-	-	PUNCT
bptjm-66	15	15	level	level	NOUN
bptjm-66	15	16	tissue	tissue	NOUN
bptjm-66	15	17	damage	damage	NOUN
bptjm-66	15	18	,	,	PUNCT
bptjm-66	15	19	representing	represent	VERB
bptjm-66	15	20	the	the	DET
bptjm-66	15	21	most	most	ADV
bptjm-66	15	22	immediate	immediate	ADJ
bptjm-66	15	23	level	level	NOUN
bptjm-66	15	24	of	of	ADP
bptjm-66	15	25	pain	pain	NOUN
bptjm-66	15	26	perception	perception	NOUN
bptjm-66	15	27	.	.	PUNCT
bptjm-66	16	1	examples	example	NOUN
bptjm-66	16	2	of	of	ADP
bptjm-66	16	3	nociceptive	nociceptive	ADJ
bptjm-66	16	4	pain	pain	NOUN
bptjm-66	16	5	include	include	VERB
bptjm-66	16	6	minor	minor	ADJ
bptjm-66	16	7	injuries	injury	NOUN
bptjm-66	16	8	such	such	ADJ
bptjm-66	16	9	as	as	ADP
bptjm-66	16	10	bruising	bruise	VERB
bptjm-66	16	11	,	,	PUNCT
bptjm-66	16	12	scratches	scratch	NOUN
bptjm-66	16	13	,	,	PUNCT
bptjm-66	16	14	and	and	CCONJ
bptjm-66	16	15	cuts	cut	NOUN
bptjm-66	16	16	,	,	PUNCT
bptjm-66	16	17	as	as	ADV
bptjm-66	16	18	well	well	ADV
bptjm-66	16	19	as	as	ADP
bptjm-66	16	20	some	some	DET
bptjm-66	16	21	deeper	deep	ADJ
bptjm-66	16	22	tissue	tissue	NOUN
bptjm-66	16	23	damage	damage	NOUN
bptjm-66	16	24	like	like	ADP
bptjm-66	16	25	fasciitis	fasciitis	NOUN
bptjm-66	16	26	,	,	PUNCT
bptjm-66	16	27	tendonitis	tendonitis	NOUN
bptjm-66	16	28	,	,	PUNCT
bptjm-66	16	29	and	and	CCONJ
bptjm-66	16	30	fractures	fracture	NOUN
bptjm-66	16	31	.	.	PUNCT
bptjm-66	17	1	nociceptive	nociceptive	ADJ
bptjm-66	17	2	pain	pain	NOUN
bptjm-66	17	3	normally	normally	ADV
bptjm-66	17	4	subsides	subside	VERB
bptjm-66	17	5	with	with	ADP
bptjm-66	17	6	time	time	NOUN
bptjm-66	17	7	,	,	PUNCT
bptjm-66	17	8	although	although	SCONJ
bptjm-66	17	9	various	various	ADJ
bptjm-66	17	10	physical	physical	ADJ
bptjm-66	17	11	therapies	therapy	NOUN
bptjm-66	17	12	and	and	CCONJ
bptjm-66	17	13	pharmacological	pharmacological	ADJ
bptjm-66	17	14	remedies	remedy	NOUN
bptjm-66	17	15	offer	offer	VERB
bptjm-66	17	16	immediate	immediate	ADJ
bptjm-66	17	17	pain	pain	NOUN
bptjm-66	17	18	alleviation	alleviation	NOUN
bptjm-66	17	19	.	.	PUNCT
bptjm-66	18	1	neuropathic	neuropathic	ADJ
bptjm-66	18	2	pain	pain	NOUN
bptjm-66	18	3	arises	arise	VERB
bptjm-66	18	4	from	from	ADP
bptjm-66	18	5	dysfunction	dysfunction	NOUN
bptjm-66	18	6	or	or	CCONJ
bptjm-66	18	7	damage	damage	NOUN
bptjm-66	18	8	to	to	ADP
bptjm-66	18	9	the	the	DET
bptjm-66	18	10	nervous	nervous	ADJ
bptjm-66	18	11	system	system	NOUN
bptjm-66	18	12	,	,	PUNCT
bptjm-66	18	13	specifically	specifically	ADV
bptjm-66	18	14	nerves	nerve	NOUN
bptjm-66	18	15	responsible	responsible	ADJ
bptjm-66	18	16	for	for	ADP
bptjm-66	18	17	transmitting	transmit	VERB
bptjm-66	18	18	pain	pain	NOUN
bptjm-66	18	19	signals	signal	NOUN
bptjm-66	18	20	to	to	ADP
bptjm-66	18	21	the	the	DET
bptjm-66	18	22	spinal	spinal	ADJ
bptjm-66	18	23	cord	cord	NOUN
bptjm-66	18	24	or	or	CCONJ
bptjm-66	18	25	brain	brain	NOUN
bptjm-66	18	26	.	.	PUNCT
bptjm-66	19	1	consequently	consequently	ADV
bptjm-66	19	2	,	,	PUNCT
bptjm-66	19	3	pain	pain	NOUN
bptjm-66	19	4	is	be	AUX
bptjm-66	19	5	perceived	perceive	VERB
bptjm-66	19	6	even	even	ADV
bptjm-66	19	7	in	in	ADP
bptjm-66	19	8	the	the	DET
bptjm-66	19	9	absence	absence	NOUN
bptjm-66	19	10	of	of	ADP
bptjm-66	19	11	external	external	ADJ
bptjm-66	19	12	stimuli	stimulus	NOUN
bptjm-66	19	13	.	.	PUNCT
bptjm-66	20	1	whether	whether	SCONJ
bptjm-66	20	2	caused	cause	VERB
bptjm-66	20	3	by	by	ADP
bptjm-66	20	4	injury	injury	NOUN
bptjm-66	20	5	,	,	PUNCT
bptjm-66	20	6	disease	disease	NOUN
bptjm-66	20	7	,	,	PUNCT
bptjm-66	20	8	or	or	CCONJ
bptjm-66	20	9	other	other	ADJ
bptjm-66	20	10	factors	factor	NOUN
bptjm-66	20	11	,	,	PUNCT
bptjm-66	20	12	damage	damage	NOUN
bptjm-66	20	13	to	to	ADP
bptjm-66	20	14	nerve	nerve	NOUN
bptjm-66	20	15	fibers	fiber	NOUN
bptjm-66	20	16	disrupt	disrupt	VERB
bptjm-66	20	17	their	their	PRON
bptjm-66	20	18	ability	ability	NOUN
bptjm-66	20	19	to	to	PART
bptjm-66	20	20	transmit	transmit	VERB
bptjm-66	20	21	accurate	accurate	ADJ
bptjm-66	20	22	signals	signal	NOUN
bptjm-66	20	23	from	from	ADP
bptjm-66	20	24	the	the	DET
bptjm-66	20	25	periphery	periphery	NOUN
bptjm-66	20	26	to	to	ADP
bptjm-66	20	27	the	the	DET
bptjm-66	20	28	central	central	ADJ
bptjm-66	20	29	nervous	nervous	ADJ
bptjm-66	20	30	system	system	NOUN
bptjm-66	20	31	.	.	PUNCT
bptjm-66	21	1	neuropathic	neuropathic	ADJ
bptjm-66	21	2	pain	pain	NOUN
bptjm-66	21	3	syndromes	syndrome	NOUN
bptjm-66	21	4	can	can	AUX
bptjm-66	21	5	include	include	VERB
bptjm-66	21	6	post	post	ADJ
bptjm-66	21	7	-	-	ADJ
bptjm-66	21	8	stroke	stroke	ADJ
bptjm-66	21	9	pain	pain	NOUN
bptjm-66	21	10	,	,	PUNCT
bptjm-66	21	11	spinal	spinal	ADJ
bptjm-66	21	12	cord	cord	NOUN
bptjm-66	21	13	injury	injury	NOUN
bptjm-66	21	14	,	,	PUNCT
bptjm-66	21	15	multiple	multiple	ADJ
bptjm-66	21	16	sclerosis	sclerosis	NOUN
bptjm-66	21	17	(	(	PUNCT
bptjm-66	21	18	ms	ms	NOUN
bptjm-66	21	19	)	)	PUNCT
bptjm-66	21	20	,	,	PUNCT
bptjm-66	21	21	and	and	CCONJ
bptjm-66	21	22	they	they	PRON
bptjm-66	21	23	have	have	AUX
bptjm-66	21	24	also	also	ADV
bptjm-66	21	25	been	be	AUX
bptjm-66	21	26	associated	associate	VERB
bptjm-66	21	27	with	with	ADP
bptjm-66	21	28	other	other	ADJ
bptjm-66	21	29	pain	pain	NOUN
bptjm-66	21	30	groups	group	NOUN
bptjm-66	21	31	.	.	PUNCT
bptjm-66	22	1	currently	currently	ADV
bptjm-66	22	2	,	,	PUNCT
bptjm-66	22	3	the	the	DET
bptjm-66	22	4	first	first	ADJ
bptjm-66	22	5	line	line	NOUN
bptjm-66	22	6	of	of	ADP
bptjm-66	22	7	treatment	treatment	NOUN
bptjm-66	22	8	for	for	ADP
bptjm-66	22	9	neuropathic	neuropathic	ADJ
bptjm-66	22	10	pain	pain	NOUN
bptjm-66	22	11	is	be	AUX
bptjm-66	22	12	using	use	VERB
bptjm-66	22	13	pharmaceuticals	pharmaceutical	NOUN
bptjm-66	22	14	which	which	PRON
bptjm-66	22	15	include	include	VERB
bptjm-66	22	16	tricyclic	tricyclic	ADJ
bptjm-66	22	17	antidepressants	antidepressant	NOUN
bptjm-66	22	18	(	(	PUNCT
bptjm-66	22	19	tca	tca	PROPN
bptjm-66	22	20	)	)	PUNCT
bptjm-66	22	21	,	,	PUNCT
bptjm-66	22	22	gabapentin	gabapentin	NOUN
bptjm-66	22	23	,	,	PUNCT
bptjm-66	22	24	anticonvulsants	anticonvulsant	NOUN
bptjm-66	22	25	,	,	PUNCT
bptjm-66	22	26	and	and	CCONJ
bptjm-66	22	27	antidepressants2	antidepressants2	NOUN
bptjm-66	22	28	.	.	PUNCT
bptjm-66	23	1	in	in	ADP
bptjm-66	23	2	addition	addition	NOUN
bptjm-66	23	3	,	,	PUNCT
bptjm-66	23	4	there	there	PRON
bptjm-66	23	5	have	have	AUX
bptjm-66	23	6	been	be	AUX
bptjm-66	23	7	recent	recent	ADJ
bptjm-66	23	8	studies	study	NOUN
bptjm-66	23	9	to	to	PART
bptjm-66	23	10	show	show	VERB
bptjm-66	23	11	botulinum	botulinum	ADJ
bptjm-66	23	12	toxin	toxin	NOUN
bptjm-66	23	13	has	have	AUX
bptjm-66	23	14	helped	help	VERB
bptjm-66	23	15	by	by	ADP
bptjm-66	23	16	inhibiting	inhibit	VERB
bptjm-66	23	17	proinflammatory	proinflammatory	ADJ
bptjm-66	23	18	mediators3	mediators3	NOUN
bptjm-66	23	19	.	.	PUNCT
bptjm-66	24	1	recognizing	recognize	VERB
bptjm-66	24	2	the	the	DET
bptjm-66	24	3	interconnectedness	interconnectedness	NOUN
bptjm-66	24	4	of	of	ADP
bptjm-66	24	5	nociceptive	nociceptive	ADJ
bptjm-66	24	6	and	and	CCONJ
bptjm-66	24	7	neuropathic	neuropathic	ADJ
bptjm-66	24	8	pain	pain	NOUN
bptjm-66	24	9	is	be	AUX
bptjm-66	24	10	vital	vital	ADJ
bptjm-66	24	11	for	for	ADP
bptjm-66	24	12	developing	develop	VERB
bptjm-66	24	13	comprehensive	comprehensive	ADJ
bptjm-66	24	14	approaches	approach	NOUN
bptjm-66	24	15	to	to	ADP
bptjm-66	24	16	pain	pain	NOUN
bptjm-66	24	17	management	management	NOUN
bptjm-66	24	18	.	.	PUNCT
bptjm-66	25	1	acute	acute	ADJ
bptjm-66	25	2	pain	pain	PROPN
bptjm-66	25	3	typically	typically	ADV
bptjm-66	25	4	subsides	subside	VERB
bptjm-66	25	5	when	when	SCONJ
bptjm-66	25	6	the	the	DET
bptjm-66	25	7	primary	primary	ADJ
bptjm-66	25	8	stimulus	stimulus	NOUN
bptjm-66	25	9	is	be	AUX
bptjm-66	25	10	removed	remove	VERB
bptjm-66	25	11	,	,	PUNCT
bptjm-66	25	12	whereas	whereas	SCONJ
bptjm-66	25	13	chronic	chronic	ADJ
bptjm-66	25	14	pain	pain	NOUN
bptjm-66	25	15	persists	persist	VERB
bptjm-66	25	16	even	even	ADV
bptjm-66	25	17	after	after	SCONJ
bptjm-66	25	18	the	the	DET
bptjm-66	25	19	primary	primary	ADJ
bptjm-66	25	20	stimulus	stimulus	NOUN
bptjm-66	25	21	is	be	AUX
bptjm-66	25	22	no	no	ADV
bptjm-66	25	23	longer	long	ADV
bptjm-66	25	24	present	present	ADJ
bptjm-66	25	25	.	.	PUNCT
bptjm-66	26	1	berkeley	berkeley	PROPN
bptjm-66	26	2	pharma	pharma	PROPN
bptjm-66	26	3	tech	tech	PROPN
bptjm-66	26	4	journal	journal	NOUN
bptjm-66	26	5	of	of	ADP
bptjm-66	26	6	medicine	medicine	NOUN
bptjm-66	26	7	|	|	ADV
bptjm-66	26	8	2	2	NUM
bptjm-66	26	9	classifying	classify	VERB
bptjm-66	26	10	pain	pain	NOUN
bptjm-66	26	11	in	in	ADP
bptjm-66	26	12	two	two	NUM
bptjm-66	26	13	broad	broad	ADJ
bptjm-66	26	14	categories	category	NOUN
bptjm-66	26	15	requires	require	VERB
bptjm-66	26	16	some	some	PRON
bptjm-66	26	17	more	more	ADJ
bptjm-66	26	18	specificity	specificity	NOUN
bptjm-66	26	19	to	to	PART
bptjm-66	26	20	obtain	obtain	VERB
bptjm-66	26	21	effective	effective	ADJ
bptjm-66	26	22	characterization	characterization	NOUN
bptjm-66	26	23	.	.	PUNCT
bptjm-66	27	1	the	the	DET
bptjm-66	27	2	different	different	ADJ
bptjm-66	27	3	conditions	condition	NOUN
bptjm-66	27	4	can	can	AUX
bptjm-66	27	5	be	be	AUX
bptjm-66	27	6	broken	break	VERB
bptjm-66	27	7	down	down	ADP
bptjm-66	27	8	into	into	ADP
bptjm-66	27	9	different	different	ADJ
bptjm-66	27	10	categories	category	NOUN
bptjm-66	27	11	in	in	ADP
bptjm-66	27	12	terms	term	NOUN
bptjm-66	27	13	of	of	ADP
bptjm-66	27	14	chronic	chronic	ADJ
bptjm-66	27	15	pain	pain	NOUN
bptjm-66	27	16	.	.	PUNCT
bptjm-66	28	1	these	these	DET
bptjm-66	28	2	groups	group	NOUN
bptjm-66	28	3	are	be	AUX
bptjm-66	28	4	inflammatory	inflammatory	ADJ
bptjm-66	28	5	,	,	PUNCT
bptjm-66	28	6	musculoskeletal	musculoskeletal	ADJ
bptjm-66	28	7	,	,	PUNCT
bptjm-66	28	8	and	and	CCONJ
bptjm-66	28	9	psychological	psychological	ADJ
bptjm-66	28	10	pain4	pain4	NOUN
bptjm-66	28	11	.	.	PUNCT
bptjm-66	29	1	inflammatory	inflammatory	ADJ
bptjm-66	29	2	pain	pain	NOUN
bptjm-66	29	3	is	be	AUX
bptjm-66	29	4	characterized	characterize	VERB
bptjm-66	29	5	by	by	ADP
bptjm-66	29	6	heightened	heighten	VERB
bptjm-66	29	7	sensitivity	sensitivity	NOUN
bptjm-66	29	8	of	of	ADP
bptjm-66	29	9	nociceptive	nociceptive	ADJ
bptjm-66	29	10	pain	pain	NOUN
bptjm-66	29	11	receptors	receptor	NOUN
bptjm-66	29	12	due	due	ADJ
bptjm-66	29	13	to	to	ADP
bptjm-66	29	14	inflammation5	inflammation5	ADJ
bptjm-66	29	15	.	.	PUNCT
bptjm-66	30	1	hallmark	hallmark	ADJ
bptjm-66	30	2	symptoms	symptom	NOUN
bptjm-66	30	3	of	of	ADP
bptjm-66	30	4	this	this	DET
bptjm-66	30	5	type	type	NOUN
bptjm-66	30	6	of	of	ADP
bptjm-66	30	7	pain	pain	NOUN
bptjm-66	30	8	include	include	VERB
bptjm-66	30	9	increased	increase	VERB
bptjm-66	30	10	pain	pain	NOUN
bptjm-66	30	11	perception	perception	NOUN
bptjm-66	30	12	,	,	PUNCT
bptjm-66	30	13	which	which	PRON
bptjm-66	30	14	is	be	AUX
bptjm-66	30	15	the	the	DET
bptjm-66	30	16	result	result	NOUN
bptjm-66	30	17	of	of	ADP
bptjm-66	30	18	the	the	DET
bptjm-66	30	19	higher	high	ADJ
bptjm-66	30	20	influx	influx	NOUN
bptjm-66	30	21	of	of	ADP
bptjm-66	30	22	pain	pain	NOUN
bptjm-66	30	23	mediators	mediator	NOUN
bptjm-66	30	24	that	that	PRON
bptjm-66	30	25	localize	localize	VERB
bptjm-66	30	26	with	with	ADP
bptjm-66	30	27	the	the	DET
bptjm-66	30	28	increase	increase	NOUN
bptjm-66	30	29	in	in	ADP
bptjm-66	30	30	blood	blood	NOUN
bptjm-66	30	31	flow	flow	NOUN
bptjm-66	30	32	.	.	PUNCT
bptjm-66	31	1	this	this	DET
bptjm-66	31	2	heightened	heighten	VERB
bptjm-66	31	3	sensitivity	sensitivity	NOUN
bptjm-66	31	4	can	can	AUX
bptjm-66	31	5	manifest	manifest	VERB
bptjm-66	31	6	as	as	ADP
bptjm-66	31	7	allodynia	allodynia	ADJ
bptjm-66	31	8	,	,	PUNCT
bptjm-66	31	9	where	where	SCONJ
bptjm-66	31	10	pain	pain	NOUN
bptjm-66	31	11	occurs	occur	VERB
bptjm-66	31	12	in	in	ADP
bptjm-66	31	13	response	response	NOUN
bptjm-66	31	14	to	to	PART
bptjm-66	31	15	stimuli	stimuli	VERB
bptjm-66	31	16	that	that	PRON
bptjm-66	31	17	would	would	AUX
bptjm-66	31	18	not	not	PART
bptjm-66	31	19	normally	normally	ADV
bptjm-66	31	20	induce	induce	VERB
bptjm-66	31	21	pain	pain	NOUN
bptjm-66	31	22	,	,	PUNCT
bptjm-66	31	23	or	or	CCONJ
bptjm-66	31	24	hyperalgesia	hyperalgesia	NOUN
bptjm-66	31	25	,	,	PUNCT
bptjm-66	31	26	an	an	DET
bptjm-66	31	27	exaggerated	exaggerated	ADJ
bptjm-66	31	28	response	response	NOUN
bptjm-66	31	29	to	to	ADP
bptjm-66	31	30	painful	painful	ADJ
bptjm-66	31	31	stimuli	stimulus	NOUN
bptjm-66	31	32	.	.	PUNCT
bptjm-66	32	1	common	common	ADJ
bptjm-66	32	2	examples	example	NOUN
bptjm-66	32	3	of	of	ADP
bptjm-66	32	4	conditions	condition	NOUN
bptjm-66	32	5	associated	associate	VERB
bptjm-66	32	6	with	with	ADP
bptjm-66	32	7	inflammatory	inflammatory	ADJ
bptjm-66	32	8	pain	pain	NOUN
bptjm-66	32	9	include	include	VERB
bptjm-66	32	10	arthritis	arthritis	NOUN
bptjm-66	32	11	and	and	CCONJ
bptjm-66	32	12	various	various	ADJ
bptjm-66	32	13	infections	infection	NOUN
bptjm-66	32	14	.	.	PUNCT
bptjm-66	33	1	surgery	surgery	NOUN
bptjm-66	33	2	and	and	CCONJ
bptjm-66	33	3	opioid	opioid	ADJ
bptjm-66	33	4	use	use	NOUN
bptjm-66	33	5	can	can	AUX
bptjm-66	33	6	also	also	ADV
bptjm-66	33	7	trigger	trigger	VERB
bptjm-66	33	8	hyperalgesia	hyperalgesia	NOUN
bptjm-66	33	9	by	by	ADP
bptjm-66	33	10	increasing	increase	VERB
bptjm-66	33	11	the	the	DET
bptjm-66	33	12	concentration	concentration	NOUN
bptjm-66	33	13	of	of	ADP
bptjm-66	33	14	calcium	calcium	NOUN
bptjm-66	33	15	and	and	CCONJ
bptjm-66	33	16	upregulating	upregulating	ADJ
bptjm-66	33	17	calcium	calcium	NOUN
bptjm-66	33	18	-	-	PUNCT
bptjm-66	33	19	dependent	dependent	ADJ
bptjm-66	33	20	kinases	kinase	NOUN
bptjm-66	33	21	,	,	PUNCT
bptjm-66	33	22	serving	serve	VERB
bptjm-66	33	23	as	as	ADP
bptjm-66	33	24	a	a	DET
bptjm-66	33	25	trigger	trigger	NOUN
bptjm-66	33	26	for	for	ADP
bptjm-66	33	27	the	the	DET
bptjm-66	33	28	release	release	NOUN
bptjm-66	33	29	of	of	ADP
bptjm-66	33	30	neurotransmitters	neurotransmitter	NOUN
bptjm-66	33	31	.	.	PUNCT
bptjm-66	34	1	the	the	DET
bptjm-66	34	2	next	next	ADJ
bptjm-66	34	3	classification	classification	NOUN
bptjm-66	34	4	of	of	ADP
bptjm-66	34	5	pain	pain	NOUN
bptjm-66	34	6	to	to	PART
bptjm-66	34	7	consider	consider	VERB
bptjm-66	34	8	is	be	AUX
bptjm-66	34	9	musculoskeletal	musculoskeletal	ADJ
bptjm-66	34	10	pain	pain	NOUN
bptjm-66	34	11	.	.	PUNCT
bptjm-66	35	1	it	it	PRON
bptjm-66	35	2	is	be	AUX
bptjm-66	35	3	highly	highly	ADV
bptjm-66	35	4	prevalent	prevalent	ADJ
bptjm-66	35	5	in	in	ADP
bptjm-66	35	6	the	the	DET
bptjm-66	35	7	general	general	ADJ
bptjm-66	35	8	population	population	NOUN
bptjm-66	35	9	,	,	PUNCT
bptjm-66	35	10	affecting	affect	VERB
bptjm-66	35	11	approximately	approximately	ADV
bptjm-66	35	12	37	37	NUM
bptjm-66	35	13	%	%	NOUN
bptjm-66	35	14	of	of	ADP
bptjm-66	35	15	the	the	DET
bptjm-66	35	16	united	united	PROPN
bptjm-66	35	17	states	states	PROPN
bptjm-66	35	18	population	population	PROPN
bptjm-66	35	19	,	,	PUNCT
bptjm-66	35	20	with	with	ADP
bptjm-66	35	21	an	an	DET
bptjm-66	35	22	economic	economic	ADJ
bptjm-66	35	23	burden	burden	NOUN
bptjm-66	35	24	of	of	ADP
bptjm-66	35	25	$	$	SYM
bptjm-66	35	26	635	635	NUM
bptjm-66	35	27	billion	billion	NUM
bptjm-66	35	28	per	per	ADP
bptjm-66	35	29	year6	year6	NOUN
bptjm-66	35	30	.	.	PUNCT
bptjm-66	36	1	musculoskeletal	musculoskeletal	ADJ
bptjm-66	36	2	pain	pain	NOUN
bptjm-66	36	3	is	be	AUX
bptjm-66	36	4	discomfort	discomfort	NOUN
bptjm-66	36	5	that	that	PRON
bptjm-66	36	6	arises	arise	VERB
bptjm-66	36	7	in	in	ADP
bptjm-66	36	8	muscles	muscle	NOUN
bptjm-66	36	9	,	,	PUNCT
bptjm-66	36	10	bones	bone	NOUN
bptjm-66	36	11	,	,	PUNCT
bptjm-66	36	12	ligaments	ligament	NOUN
bptjm-66	36	13	,	,	PUNCT
bptjm-66	36	14	tendons	tendon	NOUN
bptjm-66	36	15	,	,	PUNCT
bptjm-66	36	16	and	and	CCONJ
bptjm-66	36	17	various	various	ADJ
bptjm-66	36	18	supportive	supportive	ADJ
bptjm-66	36	19	tissues	tissue	NOUN
bptjm-66	36	20	in	in	ADP
bptjm-66	36	21	the	the	DET
bptjm-66	36	22	body	body	NOUN
bptjm-66	36	23	,	,	PUNCT
bptjm-66	36	24	as	as	ADP
bptjm-66	36	25	a	a	DET
bptjm-66	36	26	result	result	NOUN
bptjm-66	36	27	of	of	ADP
bptjm-66	36	28	defects	defect	NOUN
bptjm-66	36	29	of	of	ADP
bptjm-66	36	30	certain	certain	ADJ
bptjm-66	36	31	receptors	receptor	NOUN
bptjm-66	36	32	.	.	PUNCT
bptjm-66	37	1	the	the	DET
bptjm-66	37	2	most	most	ADV
bptjm-66	37	3	common	common	ADJ
bptjm-66	37	4	agitators	agitator	NOUN
bptjm-66	37	5	for	for	ADP
bptjm-66	37	6	this	this	DET
bptjm-66	37	7	type	type	NOUN
bptjm-66	37	8	of	of	ADP
bptjm-66	37	9	pain	pain	NOUN
bptjm-66	37	10	include	include	VERB
bptjm-66	37	11	overuse	overuse	NOUN
bptjm-66	37	12	,	,	PUNCT
bptjm-66	37	13	poor	poor	ADJ
bptjm-66	37	14	posture	posture	NOUN
bptjm-66	37	15	,	,	PUNCT
bptjm-66	37	16	and	and	CCONJ
bptjm-66	37	17	various	various	ADJ
bptjm-66	37	18	underlying	underlying	ADJ
bptjm-66	37	19	medical	medical	ADJ
bptjm-66	37	20	conditions	condition	NOUN
bptjm-66	37	21	,	,	PUNCT
bptjm-66	37	22	leading	lead	VERB
bptjm-66	37	23	to	to	ADP
bptjm-66	37	24	other	other	ADJ
bptjm-66	37	25	ailments	ailment	NOUN
bptjm-66	37	26	including	include	VERB
bptjm-66	37	27	both	both	DET
bptjm-66	37	28	osteoarthritis	osteoarthritis	NOUN
bptjm-66	37	29	and	and	CCONJ
bptjm-66	37	30	rheumatoid	rheumatoid	VERB
bptjm-66	37	31	arthritis7	arthritis7	PROPN
bptjm-66	37	32	.	.	PUNCT
bptjm-66	38	1	it	it	PRON
bptjm-66	38	2	remains	remain	VERB
bptjm-66	38	3	closely	closely	ADV
bptjm-66	38	4	connected	connect	VERB
bptjm-66	38	5	with	with	ADP
bptjm-66	38	6	inflammatory	inflammatory	ADJ
bptjm-66	38	7	pain	pain	NOUN
bptjm-66	38	8	,	,	PUNCT
bptjm-66	38	9	as	as	ADP
bptjm-66	38	10	damaging	damage	VERB
bptjm-66	38	11	the	the	DET
bptjm-66	38	12	tissue	tissue	NOUN
bptjm-66	38	13	as	as	ADP
bptjm-66	38	14	a	a	DET
bptjm-66	38	15	result	result	NOUN
bptjm-66	38	16	of	of	ADP
bptjm-66	38	17	bad	bad	ADJ
bptjm-66	38	18	posture	posture	NOUN
bptjm-66	38	19	or	or	CCONJ
bptjm-66	38	20	overuse	overuse	NOUN
bptjm-66	38	21	,	,	PUNCT
bptjm-66	38	22	may	may	AUX
bptjm-66	38	23	cause	cause	VERB
bptjm-66	38	24	inflammation	inflammation	NOUN
bptjm-66	38	25	.	.	PUNCT
bptjm-66	39	1	during	during	ADP
bptjm-66	39	2	inflammation	inflammation	NOUN
bptjm-66	39	3	or	or	CCONJ
bptjm-66	39	4	tissue	tissue	NOUN
bptjm-66	39	5	injury	injury	NOUN
bptjm-66	39	6	,	,	PUNCT
bptjm-66	39	7	damaged	damage	VERB
bptjm-66	39	8	cells	cell	NOUN
bptjm-66	39	9	and	and	CCONJ
bptjm-66	39	10	immune	immune	ADJ
bptjm-66	39	11	cells	cell	NOUN
bptjm-66	39	12	release	release	VERB
bptjm-66	39	13	a	a	DET
bptjm-66	39	14	variety	variety	NOUN
bptjm-66	39	15	of	of	ADP
bptjm-66	39	16	substances	substance	NOUN
bptjm-66	39	17	known	know	VERB
bptjm-66	39	18	as	as	ADP
bptjm-66	39	19	inflammatory	inflammatory	ADJ
bptjm-66	39	20	mediators	mediator	NOUN
bptjm-66	39	21	,	,	PUNCT
bptjm-66	39	22	such	such	ADJ
bptjm-66	39	23	as	as	ADP
bptjm-66	39	24	bradykinin	bradykinin	NOUN
bptjm-66	39	25	,	,	PUNCT
bptjm-66	39	26	nerve	nerve	NOUN
bptjm-66	39	27	growth	growth	NOUN
bptjm-66	39	28	factor	factor	NOUN
bptjm-66	39	29	(	(	PUNCT
bptjm-66	39	30	ngf	ngf	ADV
bptjm-66	39	31	)	)	PUNCT
bptjm-66	39	32	,	,	PUNCT
bptjm-66	39	33	prostaglandin	prostaglandin	NOUN
bptjm-66	39	34	e2	e2	PROPN
bptjm-66	39	35	(	(	PUNCT
bptjm-66	39	36	pge2	pge2	PROPN
bptjm-66	39	37	)	)	PUNCT
bptjm-66	39	38	,	,	PUNCT
bptjm-66	39	39	pro	pro	ADJ
bptjm-66	39	40	-	-	ADJ
bptjm-66	39	41	inflammatory	inflammatory	ADJ
bptjm-66	39	42	cytokines	cytokine	NOUN
bptjm-66	39	43	[	[	X
bptjm-66	39	44	e.g.	e.g.	ADV
bptjm-66	39	45	interleukin	interleukin	NOUN
bptjm-66	39	46	(	(	PUNCT
bptjm-66	39	47	il)-1β	il)-1β	PROPN
bptjm-66	39	48	,	,	PUNCT
bptjm-66	39	49	il-6	il-6	PRON
bptjm-66	39	50	,	,	PUNCT
bptjm-66	39	51	tumor	tumor	NOUN
bptjm-66	39	52	necrosis	necrosis	NOUN
bptjm-66	39	53	factor	factor	NOUN
bptjm-66	39	54	-	-	PUNCT
bptjm-66	39	55	α	α	X
bptjm-66	39	56	(	(	PUNCT
bptjm-66	39	57	tnf	tnf	PROPN
bptjm-66	39	58	-	-	PUNCT
bptjm-66	39	59	α	α	NOUN
bptjm-66	39	60	)	)	PUNCT
bptjm-66	39	61	]	]	PUNCT
bptjm-66	39	62	and	and	CCONJ
bptjm-66	39	63	chemokines	chemokine	NOUN
bptjm-66	39	64	(	(	PUNCT
bptjm-66	39	65	e.g.	e.g.	ADV
bptjm-66	39	66	chemokine	chemokine	ADJ
bptjm-66	39	67	ligand	ligand	NOUN
bptjm-66	39	68	2	2	NUM
bptjm-66	39	69	)	)	PUNCT
bptjm-66	39	70	.	.	PUNCT
bptjm-66	40	1	these	these	DET
bptjm-66	40	2	inflammatory	inflammatory	ADJ
bptjm-66	40	3	mediators	mediator	NOUN
bptjm-66	40	4	act	act	VERB
bptjm-66	40	5	both	both	PRON
bptjm-66	40	6	directly	directly	ADV
bptjm-66	40	7	on	on	ADP
bptjm-66	40	8	peripheral	peripheral	ADJ
bptjm-66	40	9	nociceptors	nociceptor	NOUN
bptjm-66	40	10	,	,	PUNCT
bptjm-66	40	11	eliciting	elicit	VERB
bptjm-66	40	12	sensitization	sensitization	NOUN
bptjm-66	40	13	,	,	PUNCT
bptjm-66	40	14	and	and	CCONJ
bptjm-66	40	15	indirectly	indirectly	ADV
bptjm-66	40	16	by	by	ADP
bptjm-66	40	17	promoting	promote	VERB
bptjm-66	40	18	inflammation	inflammation	NOUN
bptjm-66	40	19	and	and	CCONJ
bptjm-66	40	20	the	the	DET
bptjm-66	40	21	release	release	NOUN
bptjm-66	40	22	of	of	ADP
bptjm-66	40	23	prostaglandins8	prostaglandins8	PROPN
bptjm-66	40	24	.	.	PUNCT
bptjm-66	41	1	berkeley	berkeley	PROPN
bptjm-66	41	2	pharma	pharma	PROPN
bptjm-66	41	3	tech	tech	PROPN
bptjm-66	41	4	journal	journal	NOUN
bptjm-66	41	5	of	of	ADP
bptjm-66	41	6	medicine	medicine	NOUN
bptjm-66	41	7	|	|	ADV
bptjm-66	41	8	3	3	NUM
bptjm-66	41	9	psychological	psychological	ADJ
bptjm-66	41	10	pain	pain	NOUN
bptjm-66	41	11	is	be	AUX
bptjm-66	41	12	relatively	relatively	ADV
bptjm-66	41	13	a	a	DET
bptjm-66	41	14	new	new	ADJ
bptjm-66	41	15	term	term	NOUN
bptjm-66	41	16	and	and	CCONJ
bptjm-66	41	17	is	be	AUX
bptjm-66	41	18	still	still	ADV
bptjm-66	41	19	being	be	AUX
bptjm-66	41	20	discussed	discuss	VERB
bptjm-66	41	21	as	as	ADP
bptjm-66	41	22	to	to	ADP
bptjm-66	41	23	what	what	PRON
bptjm-66	41	24	the	the	DET
bptjm-66	41	25	full	full	ADJ
bptjm-66	41	26	criteria	criterion	NOUN
bptjm-66	41	27	are	be	AUX
bptjm-66	41	28	.	.	PUNCT
bptjm-66	42	1	it	it	PRON
bptjm-66	42	2	is	be	AUX
bptjm-66	42	3	generally	generally	ADV
bptjm-66	42	4	being	be	AUX
bptjm-66	42	5	discussed	discuss	VERB
bptjm-66	42	6	as	as	ADP
bptjm-66	42	7	relating	relate	VERB
bptjm-66	42	8	to	to	ADP
bptjm-66	42	9	either	either	CCONJ
bptjm-66	42	10	psychological	psychological	ADJ
bptjm-66	42	11	disorders	disorder	NOUN
bptjm-66	42	12	such	such	ADJ
bptjm-66	42	13	as	as	ADP
bptjm-66	42	14	severe	severe	ADJ
bptjm-66	42	15	depression	depression	NOUN
bptjm-66	42	16	or	or	CCONJ
bptjm-66	42	17	relating	relate	VERB
bptjm-66	42	18	to	to	ADP
bptjm-66	42	19	physical	physical	ADJ
bptjm-66	42	20	pain	pain	NOUN
bptjm-66	42	21	like	like	ADP
bptjm-66	42	22	migraines	migraine	NOUN
bptjm-66	42	23	and	and	CCONJ
bptjm-66	42	24	headaches9	headaches9	PROPN
bptjm-66	42	25	.	.	PUNCT
bptjm-66	43	1	in	in	ADP
bptjm-66	43	2	addition	addition	NOUN
bptjm-66	43	3	,	,	PUNCT
bptjm-66	43	4	due	due	ADP
bptjm-66	43	5	to	to	ADP
bptjm-66	43	6	the	the	DET
bptjm-66	43	7	developing	develop	VERB
bptjm-66	43	8	research	research	NOUN
bptjm-66	43	9	on	on	ADP
bptjm-66	43	10	this	this	DET
bptjm-66	43	11	type	type	NOUN
bptjm-66	43	12	of	of	ADP
bptjm-66	43	13	pain	pain	NOUN
bptjm-66	43	14	,	,	PUNCT
bptjm-66	43	15	there	there	PRON
bptjm-66	43	16	is	be	VERB
bptjm-66	43	17	no	no	DET
bptjm-66	43	18	definite	definite	ADJ
bptjm-66	43	19	way	way	NOUN
bptjm-66	43	20	to	to	PART
bptjm-66	43	21	treat	treat	VERB
bptjm-66	43	22	this	this	DET
bptjm-66	43	23	type	type	NOUN
bptjm-66	43	24	of	of	ADP
bptjm-66	43	25	pain	pain	NOUN
bptjm-66	43	26	and	and	CCONJ
bptjm-66	43	27	no	no	DET
bptjm-66	43	28	concrete	concrete	ADJ
bptjm-66	43	29	definition	definition	NOUN
bptjm-66	43	30	of	of	ADP
bptjm-66	43	31	this	this	DET
bptjm-66	43	32	pain	pain	NOUN
bptjm-66	43	33	yet	yet	ADV
bptjm-66	43	34	.	.	PUNCT
bptjm-66	44	1	across	across	ADP
bptjm-66	44	2	various	various	ADJ
bptjm-66	44	3	pain	pain	NOUN
bptjm-66	44	4	classifications	classification	NOUN
bptjm-66	44	5	,	,	PUNCT
bptjm-66	44	6	a	a	DET
bptjm-66	44	7	shared	share	VERB
bptjm-66	44	8	pathway	pathway	NOUN
bptjm-66	44	9	of	of	ADP
bptjm-66	44	10	pain	pain	NOUN
bptjm-66	44	11	reception	reception	NOUN
bptjm-66	44	12	emerges	emerge	NOUN
bptjm-66	44	13	,	,	PUNCT
bptjm-66	44	14	initiated	initiate	VERB
bptjm-66	44	15	by	by	ADP
bptjm-66	44	16	a	a	DET
bptjm-66	44	17	-	-	PUNCT
bptjm-66	44	18	delta	delta	NOUN
bptjm-66	44	19	and	and	CCONJ
bptjm-66	44	20	c	c	NOUN
bptjm-66	44	21	-	-	PUNCT
bptjm-66	44	22	fibers	fiber	NOUN
bptjm-66	44	23	–	–	PUNCT
bptjm-66	44	24	a	a	DET
bptjm-66	44	25	-	-	PUNCT
bptjm-66	44	26	delta	delta	NOUN
bptjm-66	44	27	fibers	fiber	NOUN
bptjm-66	44	28	emit	emit	VERB
bptjm-66	44	29	rapid	rapid	ADJ
bptjm-66	44	30	and	and	CCONJ
bptjm-66	44	31	localized	localized	ADJ
bptjm-66	44	32	signals	signal	NOUN
bptjm-66	44	33	,	,	PUNCT
bptjm-66	44	34	while	while	SCONJ
bptjm-66	44	35	c	c	NOUN
bptjm-66	44	36	-	-	PUNCT
bptjm-66	44	37	fibers	fiber	NOUN
bptjm-66	44	38	transmit	transmit	VERB
bptjm-66	44	39	non	non	ADJ
bptjm-66	44	40	-	-	ADJ
bptjm-66	44	41	localized	localized	ADJ
bptjm-66	44	42	pain	pain	NOUN
bptjm-66	44	43	signals10	signals10	NOUN
bptjm-66	44	44	.	.	PUNCT
bptjm-66	45	1	these	these	DET
bptjm-66	45	2	primary	primary	ADJ
bptjm-66	45	3	afferent	afferent	NOUN
bptjm-66	45	4	axons	axon	NOUN
bptjm-66	45	5	serve	serve	VERB
bptjm-66	45	6	as	as	ADP
bptjm-66	45	7	modalities	modality	NOUN
bptjm-66	45	8	for	for	ADP
bptjm-66	45	9	sensory	sensory	ADJ
bptjm-66	45	10	perception	perception	NOUN
bptjm-66	45	11	,	,	PUNCT
bptjm-66	45	12	transducing	transduce	VERB
bptjm-66	45	13	pain	pain	NOUN
bptjm-66	45	14	signals	signal	NOUN
bptjm-66	45	15	from	from	ADP
bptjm-66	45	16	chemical	chemical	NOUN
bptjm-66	45	17	to	to	ADP
bptjm-66	45	18	electrical	electrical	ADJ
bptjm-66	45	19	within	within	ADP
bptjm-66	45	20	neurons	neuron	NOUN
bptjm-66	45	21	.	.	PUNCT
bptjm-66	46	1	the	the	DET
bptjm-66	46	2	electrical	electrical	ADJ
bptjm-66	46	3	signals	signal	NOUN
bptjm-66	46	4	are	be	AUX
bptjm-66	46	5	transmitted	transmit	VERB
bptjm-66	46	6	along	along	ADP
bptjm-66	46	7	neuronal	neuronal	ADJ
bptjm-66	46	8	pathways	pathway	NOUN
bptjm-66	46	9	to	to	ADP
bptjm-66	46	10	the	the	DET
bptjm-66	46	11	central	central	ADJ
bptjm-66	46	12	nervous	nervous	ADJ
bptjm-66	46	13	system	system	NOUN
bptjm-66	46	14	.	.	PUNCT
bptjm-66	47	1	upon	upon	SCONJ
bptjm-66	47	2	reaching	reach	VERB
bptjm-66	47	3	synapses	synapsis	NOUN
bptjm-66	47	4	,	,	PUNCT
bptjm-66	47	5	axons	axon	NOUN
bptjm-66	47	6	convert	convert	VERB
bptjm-66	47	7	electrical	electrical	ADJ
bptjm-66	47	8	signals	signal	NOUN
bptjm-66	47	9	into	into	ADP
bptjm-66	47	10	chemical	chemical	ADJ
bptjm-66	47	11	signals	signal	NOUN
bptjm-66	47	12	,	,	PUNCT
bptjm-66	47	13	which	which	PRON
bptjm-66	47	14	are	be	AUX
bptjm-66	47	15	then	then	ADV
bptjm-66	47	16	reconverted	reconvert	VERB
bptjm-66	47	17	into	into	ADP
bptjm-66	47	18	electrical	electrical	ADJ
bptjm-66	47	19	signals	signal	NOUN
bptjm-66	47	20	upon	upon	SCONJ
bptjm-66	47	21	reception	reception	NOUN
bptjm-66	47	22	by	by	ADP
bptjm-66	47	23	dendritic	dendritic	ADJ
bptjm-66	47	24	cells	cell	NOUN
bptjm-66	47	25	.	.	PUNCT
bptjm-66	48	1	the	the	DET
bptjm-66	48	2	presence	presence	NOUN
bptjm-66	48	3	of	of	ADP
bptjm-66	48	4	myelinated	myelinated	ADJ
bptjm-66	48	5	sheaths	sheath	NOUN
bptjm-66	48	6	serves	serve	VERB
bptjm-66	48	7	to	to	PART
bptjm-66	48	8	expedite	expedite	VERB
bptjm-66	48	9	conduction	conduction	NOUN
bptjm-66	48	10	speed	speed	NOUN
bptjm-66	48	11	along	along	ADP
bptjm-66	48	12	these	these	DET
bptjm-66	48	13	pathways	pathway	NOUN
bptjm-66	48	14	.	.	PUNCT
bptjm-66	49	1	notably	notably	ADV
bptjm-66	49	2	,	,	PUNCT
bptjm-66	49	3	ions	ion	NOUN
bptjm-66	49	4	such	such	ADJ
bptjm-66	49	5	as	as	ADP
bptjm-66	49	6	calcium	calcium	NOUN
bptjm-66	49	7	,	,	PUNCT
bptjm-66	49	8	potassium	potassium	NOUN
bptjm-66	49	9	,	,	PUNCT
bptjm-66	49	10	and	and	CCONJ
bptjm-66	49	11	sodium	sodium	NOUN
bptjm-66	49	12	play	play	VERB
bptjm-66	49	13	crucial	crucial	ADJ
bptjm-66	49	14	roles	role	NOUN
bptjm-66	49	15	in	in	ADP
bptjm-66	49	16	the	the	DET
bptjm-66	49	17	transmission	transmission	NOUN
bptjm-66	49	18	of	of	ADP
bptjm-66	49	19	these	these	DET
bptjm-66	49	20	neurotransmitters	neurotransmitter	NOUN
bptjm-66	49	21	.	.	PUNCT
bptjm-66	50	1	at	at	ADP
bptjm-66	50	2	a	a	DET
bptjm-66	50	3	broader	broad	ADJ
bptjm-66	50	4	level	level	NOUN
bptjm-66	50	5	,	,	PUNCT
bptjm-66	50	6	stimulatory	stimulatory	ADJ
bptjm-66	50	7	molecules	molecule	NOUN
bptjm-66	50	8	,	,	PUNCT
bptjm-66	50	9	including	include	VERB
bptjm-66	50	10	various	various	ADJ
bptjm-66	50	11	growth	growth	NOUN
bptjm-66	50	12	factors	factor	NOUN
bptjm-66	50	13	,	,	PUNCT
bptjm-66	50	14	prostaglandins	prostaglandin	NOUN
bptjm-66	50	15	,	,	PUNCT
bptjm-66	50	16	and	and	CCONJ
bptjm-66	50	17	proteases	protease	NOUN
bptjm-66	50	18	are	be	AUX
bptjm-66	50	19	released	release	VERB
bptjm-66	50	20	upon	upon	SCONJ
bptjm-66	50	21	contact	contact	NOUN
bptjm-66	50	22	with	with	ADP
bptjm-66	50	23	noxious	noxious	ADJ
bptjm-66	50	24	stimuli	stimulus	NOUN
bptjm-66	50	25	.	.	PUNCT
bptjm-66	51	1	these	these	DET
bptjm-66	51	2	molecules	molecule	NOUN
bptjm-66	51	3	then	then	ADV
bptjm-66	51	4	access	access	VERB
bptjm-66	51	5	various	various	ADJ
bptjm-66	51	6	channels	channel	NOUN
bptjm-66	51	7	,	,	PUNCT
bptjm-66	51	8	which	which	PRON
bptjm-66	51	9	facilitates	facilitate	VERB
bptjm-66	51	10	the	the	DET
bptjm-66	51	11	release	release	NOUN
bptjm-66	51	12	of	of	ADP
bptjm-66	51	13	more	more	ADJ
bptjm-66	51	14	pain	pain	NOUN
bptjm-66	51	15	mediators	mediator	NOUN
bptjm-66	51	16	from	from	ADP
bptjm-66	51	17	nerve	nerve	NOUN
bptjm-66	51	18	terminals	terminal	NOUN
bptjm-66	51	19	,	,	PUNCT
bptjm-66	51	20	such	such	ADJ
bptjm-66	51	21	as	as	ADP
bptjm-66	51	22	glutamate	glutamate	NOUN
bptjm-66	51	23	and	and	CCONJ
bptjm-66	51	24	interleukins	interleukin	NOUN
bptjm-66	51	25	.	.	PUNCT
bptjm-66	52	1	the	the	DET
bptjm-66	52	2	signals	signal	NOUN
bptjm-66	52	3	are	be	AUX
bptjm-66	52	4	then	then	ADV
bptjm-66	52	5	sent	send	VERB
bptjm-66	52	6	to	to	ADP
bptjm-66	52	7	the	the	DET
bptjm-66	52	8	central	central	ADJ
bptjm-66	52	9	nervous	nervous	ADJ
bptjm-66	52	10	system	system	NOUN
bptjm-66	52	11	,	,	PUNCT
bptjm-66	52	12	specifically	specifically	ADV
bptjm-66	52	13	the	the	DET
bptjm-66	52	14	spinal	spinal	ADJ
bptjm-66	52	15	cord	cord	NOUN
bptjm-66	52	16	or	or	CCONJ
bptjm-66	52	17	dorsal	dorsal	NOUN
bptjm-66	52	18	horn	horn	NOUN
bptjm-66	52	19	,	,	PUNCT
bptjm-66	52	20	where	where	SCONJ
bptjm-66	52	21	they	they	PRON
bptjm-66	52	22	are	be	AUX
bptjm-66	52	23	interpreted	interpret	VERB
bptjm-66	52	24	in	in	ADP
bptjm-66	52	25	the	the	DET
bptjm-66	52	26	primary	primary	ADJ
bptjm-66	52	27	sensory	sensory	ADJ
bptjm-66	52	28	cortex	cortex	NOUN
bptjm-66	52	29	.	.	PUNCT
bptjm-66	53	1	understanding	understand	VERB
bptjm-66	53	2	the	the	DET
bptjm-66	53	3	intricacies	intricacy	NOUN
bptjm-66	53	4	of	of	ADP
bptjm-66	53	5	this	this	DET
bptjm-66	53	6	pain	pain	NOUN
bptjm-66	53	7	perception	perception	NOUN
bptjm-66	53	8	pathway	pathway	NOUN
bptjm-66	53	9	is	be	AUX
bptjm-66	53	10	essential	essential	ADJ
bptjm-66	53	11	for	for	ADP
bptjm-66	53	12	elucidating	elucidate	VERB
bptjm-66	53	13	mechanisms	mechanism	NOUN
bptjm-66	53	14	behind	behind	ADP
bptjm-66	53	15	pain	pain	NOUN
bptjm-66	53	16	perception	perception	NOUN
bptjm-66	53	17	and	and	CCONJ
bptjm-66	53	18	advancing	advance	VERB
bptjm-66	53	19	targeted	target	VERB
bptjm-66	53	20	therapeutic	therapeutic	ADJ
bptjm-66	53	21	modalities	modality	NOUN
bptjm-66	53	22	.	.	PUNCT
bptjm-66	54	1	1.2	1.2	NUM
bptjm-66	54	2	physiology	physiology	NOUN
bptjm-66	54	3	of	of	ADP
bptjm-66	54	4	pain	pain	NOUN
bptjm-66	54	5	having	having	AUX
bptjm-66	54	6	understood	understand	VERB
bptjm-66	54	7	the	the	DET
bptjm-66	54	8	pain	pain	NOUN
bptjm-66	54	9	reception	reception	NOUN
bptjm-66	54	10	mechanisms	mechanism	NOUN
bptjm-66	54	11	and	and	CCONJ
bptjm-66	54	12	pathways	pathway	NOUN
bptjm-66	54	13	,	,	PUNCT
bptjm-66	54	14	the	the	DET
bptjm-66	54	15	next	next	ADJ
bptjm-66	54	16	step	step	NOUN
bptjm-66	54	17	in	in	ADP
bptjm-66	54	18	designing	design	VERB
bptjm-66	54	19	an	an	DET
bptjm-66	54	20	effective	effective	ADJ
bptjm-66	54	21	pain	pain	NOUN
bptjm-66	54	22	medicine	medicine	NOUN
bptjm-66	54	23	is	be	AUX
bptjm-66	54	24	identifying	identify	VERB
bptjm-66	54	25	proper	proper	ADJ
bptjm-66	54	26	targets	target	NOUN
bptjm-66	54	27	.	.	PUNCT
bptjm-66	55	1	some	some	PRON
bptjm-66	55	2	of	of	ADP
bptjm-66	55	3	the	the	DET
bptjm-66	55	4	mediators	mediator	NOUN
bptjm-66	55	5	previously	previously	ADV
bptjm-66	55	6	discussed	discuss	VERB
bptjm-66	55	7	,	,	PUNCT
bptjm-66	55	8	like	like	ADP
bptjm-66	55	9	glutamate	glutamate	NOUN
bptjm-66	55	10	,	,	PUNCT
bptjm-66	55	11	have	have	VERB
bptjm-66	55	12	significant	significant	ADJ
bptjm-66	55	13	interactions	interaction	NOUN
bptjm-66	55	14	with	with	ADP
bptjm-66	55	15	nmda	nmda	ADJ
bptjm-66	55	16	pain	pain	NOUN
bptjm-66	55	17	receptors	receptor	NOUN
bptjm-66	55	18	,	,	PUNCT
bptjm-66	55	19	primarily	primarily	ADV
bptjm-66	55	20	situated	situate	VERB
bptjm-66	55	21	in	in	ADP
bptjm-66	55	22	the	the	DET
bptjm-66	55	23	central	central	ADJ
bptjm-66	55	24	nervous	nervous	ADJ
bptjm-66	55	25	system	system	NOUN
bptjm-66	55	26	.	.	PUNCT
bptjm-66	56	1	this	this	DET
bptjm-66	56	2	interaction	interaction	NOUN
bptjm-66	56	3	heightens	heighten	VERB
bptjm-66	56	4	sensitivity	sensitivity	NOUN
bptjm-66	56	5	to	to	ADP
bptjm-66	56	6	pain	pain	NOUN
bptjm-66	56	7	while	while	SCONJ
bptjm-66	56	8	berkeley	berkeley	PROPN
bptjm-66	56	9	pharma	pharma	PROPN
bptjm-66	56	10	tech	tech	NOUN
bptjm-66	56	11	journal	journal	NOUN
bptjm-66	56	12	of	of	ADP
bptjm-66	56	13	medicine	medicine	NOUN
bptjm-66	56	14	|	|	ADV
bptjm-66	56	15	4	4	NUM
bptjm-66	56	16	simultaneously	simultaneously	ADV
bptjm-66	56	17	reducing	reduce	VERB
bptjm-66	56	18	the	the	DET
bptjm-66	56	19	effectiveness	effectiveness	NOUN
bptjm-66	56	20	of	of	ADP
bptjm-66	56	21	opioid	opioid	ADJ
bptjm-66	56	22	receptor	receptor	NOUN
bptjm-66	56	23	agents	agent	NOUN
bptjm-66	56	24	.	.	PUNCT
bptjm-66	57	1	therefore	therefore	ADV
bptjm-66	57	2	,	,	PUNCT
bptjm-66	57	3	n	n	CCONJ
bptjm-66	57	4	-	-	PUNCT
bptjm-66	57	5	methyl	methyl	NOUN
bptjm-66	57	6	-	-	PUNCT
bptjm-66	57	7	d	d	NOUN
bptjm-66	57	8	-	-	NOUN
bptjm-66	57	9	aspartate	aspartate	ADJ
bptjm-66	57	10	(	(	PUNCT
bptjm-66	57	11	nmda	nmda	ADJ
bptjm-66	57	12	)	)	PUNCT
bptjm-66	57	13	receptor	receptor	NOUN
bptjm-66	57	14	-	-	PUNCT
bptjm-66	57	15	targeted	target	VERB
bptjm-66	57	16	modalities	modality	NOUN
bptjm-66	57	17	involve	involve	VERB
bptjm-66	57	18	much	much	ADJ
bptjm-66	57	19	of	of	ADP
bptjm-66	57	20	the	the	DET
bptjm-66	57	21	research	research	NOUN
bptjm-66	57	22	in	in	ADP
bptjm-66	57	23	pain	pain	NOUN
bptjm-66	57	24	medicine11	medicine11	NOUN
bptjm-66	57	25	.	.	PUNCT
bptjm-66	58	1	another	another	DET
bptjm-66	58	2	receptor	receptor	NOUN
bptjm-66	58	3	of	of	ADP
bptjm-66	58	4	interest	interest	NOUN
bptjm-66	58	5	,	,	PUNCT
bptjm-66	58	6	dopamine	dopamine	NOUN
bptjm-66	58	7	,	,	PUNCT
bptjm-66	58	8	is	be	AUX
bptjm-66	58	9	classified	classify	VERB
bptjm-66	58	10	into	into	ADP
bptjm-66	58	11	different	different	ADJ
bptjm-66	58	12	types	type	NOUN
bptjm-66	58	13	,	,	PUNCT
bptjm-66	58	14	each	each	PRON
bptjm-66	58	15	with	with	ADP
bptjm-66	58	16	distinct	distinct	ADJ
bptjm-66	58	17	roles	role	NOUN
bptjm-66	58	18	in	in	ADP
bptjm-66	58	19	pain	pain	NOUN
bptjm-66	58	20	modulation	modulation	NOUN
bptjm-66	58	21	.	.	PUNCT
bptjm-66	59	1	d1	d1	PROPN
bptjm-66	59	2	dopamine	dopamine	NOUN
bptjm-66	59	3	receptors	receptor	NOUN
bptjm-66	59	4	,	,	PUNCT
bptjm-66	59	5	for	for	ADP
bptjm-66	59	6	instance	instance	NOUN
bptjm-66	59	7	,	,	PUNCT
bptjm-66	59	8	trigger	trigger	VERB
bptjm-66	59	9	the	the	DET
bptjm-66	59	10	production	production	NOUN
bptjm-66	59	11	of	of	ADP
bptjm-66	59	12	higher	high	ADJ
bptjm-66	59	13	levels	level	NOUN
bptjm-66	59	14	of	of	ADP
bptjm-66	59	15	camp	camp	NOUN
bptjm-66	59	16	(	(	PUNCT
bptjm-66	59	17	cyclic	cyclic	ADJ
bptjm-66	59	18	-	-	PUNCT
bptjm-66	59	19	adenosine	adenosine	NOUN
bptjm-66	59	20	-	-	PUNCT
bptjm-66	59	21	monophosphate	monophosphate	NOUN
bptjm-66	59	22	)	)	PUNCT
bptjm-66	59	23	,	,	PUNCT
bptjm-66	59	24	which	which	PRON
bptjm-66	59	25	in	in	ADP
bptjm-66	59	26	turn	turn	NOUN
bptjm-66	59	27	enhances	enhance	VERB
bptjm-66	59	28	pka	pka	NOUN
bptjm-66	59	29	(	(	PUNCT
bptjm-66	59	30	protein	protein	NOUN
bptjm-66	59	31	kinase	kinase	NOUN
bptjm-66	59	32	a	a	PRON
bptjm-66	59	33	)	)	PUNCT
bptjm-66	59	34	activity	activity	NOUN
bptjm-66	59	35	.	.	PUNCT
bptjm-66	60	1	in	in	ADP
bptjm-66	60	2	contrast	contrast	NOUN
bptjm-66	60	3	,	,	PUNCT
bptjm-66	60	4	d2	d2	NOUN
bptjm-66	60	5	dopamine	dopamine	NOUN
bptjm-66	60	6	receptors	receptor	NOUN
bptjm-66	60	7	inhibit	inhibit	VERB
bptjm-66	60	8	camp	camp	NOUN
bptjm-66	60	9	and	and	CCONJ
bptjm-66	60	10	pka	pka	NOUN
bptjm-66	60	11	activity	activity	NOUN
bptjm-66	60	12	,	,	PUNCT
bptjm-66	60	13	exerting	exert	VERB
bptjm-66	60	14	an	an	DET
bptjm-66	60	15	opposing	opposing	ADJ
bptjm-66	60	16	effect	effect	NOUN
bptjm-66	60	17	on	on	ADP
bptjm-66	60	18	d1	d1	ADJ
bptjm-66	60	19	receptors	receptor	NOUN
bptjm-66	60	20	.	.	PUNCT
bptjm-66	61	1	d1	d1	NOUN
bptjm-66	61	2	receptors	receptor	NOUN
bptjm-66	61	3	play	play	VERB
bptjm-66	61	4	a	a	DET
bptjm-66	61	5	role	role	NOUN
bptjm-66	61	6	in	in	ADP
bptjm-66	61	7	pain	pain	NOUN
bptjm-66	61	8	development	development	NOUN
bptjm-66	61	9	and	and	CCONJ
bptjm-66	61	10	maintenance	maintenance	NOUN
bptjm-66	61	11	,	,	PUNCT
bptjm-66	61	12	while	while	SCONJ
bptjm-66	61	13	d2	d2	NOUN
bptjm-66	61	14	receptors	receptor	NOUN
bptjm-66	61	15	act	act	VERB
bptjm-66	61	16	to	to	PART
bptjm-66	61	17	block	block	VERB
bptjm-66	61	18	pain	pain	NOUN
bptjm-66	61	19	signals	signal	NOUN
bptjm-66	61	20	.	.	PUNCT
bptjm-66	62	1	shifting	shift	VERB
bptjm-66	62	2	our	our	PRON
bptjm-66	62	3	focus	focus	NOUN
bptjm-66	62	4	to	to	ADP
bptjm-66	62	5	opioids	opioid	NOUN
bptjm-66	62	6	;	;	PUNCT
bptjm-66	62	7	there	there	PRON
bptjm-66	62	8	are	be	VERB
bptjm-66	62	9	three	three	NUM
bptjm-66	62	10	main	main	ADJ
bptjm-66	62	11	types	type	NOUN
bptjm-66	62	12	of	of	ADP
bptjm-66	62	13	opioid	opioid	ADJ
bptjm-66	62	14	receptors	receptor	NOUN
bptjm-66	62	15	:	:	PUNCT
bptjm-66	62	16	delta	delta	NOUN
bptjm-66	62	17	-	-	PUNCT
bptjm-66	62	18	opioid	opioid	ADJ
bptjm-66	62	19	peptide	peptide	NOUN
bptjm-66	62	20	/	/	SYM
bptjm-66	62	21	receptor	receptor	NOUN
bptjm-66	62	22	(	(	PUNCT
bptjm-66	62	23	dop	dop	NOUN
bptjm-66	62	24	)	)	PUNCT
bptjm-66	62	25	,	,	PUNCT
bptjm-66	62	26	kappa	kappa	ADJ
bptjm-66	62	27	-	-	ADJ
bptjm-66	62	28	opioid	opioid	ADJ
bptjm-66	62	29	peptide	peptide	NOUN
bptjm-66	62	30	/	/	SYM
bptjm-66	62	31	receptor	receptor	NOUN
bptjm-66	62	32	(	(	PUNCT
bptjm-66	62	33	kop	kop	PROPN
bptjm-66	62	34	)	)	PUNCT
bptjm-66	62	35	,	,	PUNCT
bptjm-66	62	36	and	and	CCONJ
bptjm-66	62	37	mu	mu	NOUN
bptjm-66	62	38	-	-	PUNCT
bptjm-66	62	39	opioid	opioid	NOUN
bptjm-66	62	40	peptide	peptide	NOUN
bptjm-66	62	41	/	/	SYM
bptjm-66	62	42	receptor	receptor	NOUN
bptjm-66	62	43	(	(	PUNCT
bptjm-66	62	44	mop	mop	PROPN
bptjm-66	62	45	)	)	PUNCT
bptjm-66	62	46	,	,	PUNCT
bptjm-66	62	47	each	each	PRON
bptjm-66	62	48	with	with	ADP
bptjm-66	62	49	their	their	PRON
bptjm-66	62	50	subtypes	subtype	NOUN
bptjm-66	62	51	.	.	PUNCT
bptjm-66	63	1	in	in	ADP
bptjm-66	63	2	addition	addition	NOUN
bptjm-66	63	3	,	,	PUNCT
bptjm-66	63	4	there	there	PRON
bptjm-66	63	5	is	be	VERB
bptjm-66	63	6	a	a	DET
bptjm-66	63	7	fourth	fourth	ADJ
bptjm-66	63	8	receptor	receptor	NOUN
bptjm-66	63	9	named	name	VERB
bptjm-66	63	10	nociception	nociception	NOUN
bptjm-66	63	11	receptor	receptor	NOUN
bptjm-66	63	12	(	(	PUNCT
bptjm-66	63	13	nop	nop	PROPN
bptjm-66	63	14	)	)	PUNCT
bptjm-66	63	15	that	that	PRON
bptjm-66	63	16	is	be	AUX
bptjm-66	63	17	considered	consider	VERB
bptjm-66	63	18	a	a	DET
bptjm-66	63	19	non	non	ADJ
bptjm-66	63	20	-	-	ADJ
bptjm-66	63	21	opioid	opioid	ADJ
bptjm-66	63	22	receptor	receptor	NOUN
bptjm-66	63	23	of	of	ADP
bptjm-66	63	24	the	the	DET
bptjm-66	63	25	opioid	opioid	ADJ
bptjm-66	63	26	receptor	receptor	NOUN
bptjm-66	63	27	family	family	NOUN
bptjm-66	63	28	.	.	PUNCT
bptjm-66	64	1	nop	nop	PROPN
bptjm-66	64	2	works	work	VERB
bptjm-66	64	3	similarly	similarly	ADV
bptjm-66	64	4	to	to	ADP
bptjm-66	64	5	the	the	DET
bptjm-66	64	6	opioid	opioid	ADJ
bptjm-66	64	7	receptors	receptor	NOUN
bptjm-66	64	8	but	but	CCONJ
bptjm-66	64	9	does	do	AUX
bptjm-66	64	10	not	not	PART
bptjm-66	64	11	bind	bind	VERB
bptjm-66	64	12	or	or	CCONJ
bptjm-66	64	13	become	become	AUX
bptjm-66	64	14	affected	affect	VERB
bptjm-66	64	15	by	by	ADP
bptjm-66	64	16	naloxone	naloxone	NOUN
bptjm-66	64	17	,	,	PUNCT
bptjm-66	64	18	the	the	DET
bptjm-66	64	19	common	common	ADJ
bptjm-66	64	20	opioid	opioid	ADJ
bptjm-66	64	21	antagonist	antagonist	NOUN
bptjm-66	64	22	.	.	PUNCT
bptjm-66	65	1	due	due	ADP
bptjm-66	65	2	to	to	ADP
bptjm-66	65	3	its	its	PRON
bptjm-66	65	4	lack	lack	NOUN
bptjm-66	65	5	of	of	ADP
bptjm-66	65	6	response	response	NOUN
bptjm-66	65	7	to	to	ADP
bptjm-66	65	8	naloxone	naloxone	NOUN
bptjm-66	65	9	,	,	PUNCT
bptjm-66	65	10	it	it	PRON
bptjm-66	65	11	is	be	AUX
bptjm-66	65	12	frequently	frequently	ADV
bptjm-66	65	13	questioned	question	VERB
bptjm-66	65	14	if	if	SCONJ
bptjm-66	65	15	the	the	DET
bptjm-66	65	16	classification	classification	NOUN
bptjm-66	65	17	of	of	ADP
bptjm-66	65	18	the	the	DET
bptjm-66	65	19	opioid	opioid	ADJ
bptjm-66	65	20	receptor	receptor	NOUN
bptjm-66	65	21	is	be	AUX
bptjm-66	65	22	correct	correct	ADJ
bptjm-66	65	23	.	.	PUNCT
bptjm-66	66	1	activation	activation	NOUN
bptjm-66	66	2	of	of	ADP
bptjm-66	66	3	dop	dop	NOUN
bptjm-66	66	4	receptors	receptor	NOUN
bptjm-66	66	5	may	may	AUX
bptjm-66	66	6	lead	lead	VERB
bptjm-66	66	7	to	to	ADP
bptjm-66	66	8	spinal	spinal	ADJ
bptjm-66	66	9	analgesia	analgesia	NOUN
bptjm-66	66	10	and	and	CCONJ
bptjm-66	66	11	reduced	reduce	VERB
bptjm-66	66	12	gastric	gastric	ADJ
bptjm-66	66	13	motility12	motility12	NOUN
bptjm-66	66	14	.	.	PUNCT
bptjm-66	67	1	kop	kop	PROPN
bptjm-66	67	2	receptor	receptor	NOUN
bptjm-66	67	3	activation	activation	NOUN
bptjm-66	67	4	also	also	ADV
bptjm-66	67	5	induces	induce	VERB
bptjm-66	67	6	spinal	spinal	ADJ
bptjm-66	67	7	analgesia	analgesia	NOUN
bptjm-66	67	8	but	but	CCONJ
bptjm-66	67	9	may	may	AUX
bptjm-66	67	10	increase	increase	VERB
bptjm-66	67	11	urination	urination	NOUN
bptjm-66	67	12	and	and	CCONJ
bptjm-66	67	13	raise	raise	VERB
bptjm-66	67	14	the	the	DET
bptjm-66	67	15	risk	risk	NOUN
bptjm-66	67	16	of	of	ADP
bptjm-66	67	17	depression	depression	NOUN
bptjm-66	67	18	.	.	PUNCT
bptjm-66	68	1	mop	mop	NOUN
bptjm-66	68	2	receptor	receptor	NOUN
bptjm-66	68	3	activation	activation	NOUN
bptjm-66	68	4	provides	provide	VERB
bptjm-66	68	5	analgesic	analgesic	ADJ
bptjm-66	68	6	effects	effect	NOUN
bptjm-66	68	7	but	but	CCONJ
bptjm-66	68	8	can	can	AUX
bptjm-66	68	9	lead	lead	VERB
bptjm-66	68	10	to	to	ADP
bptjm-66	68	11	respiratory	respiratory	ADJ
bptjm-66	68	12	depression	depression	NOUN
bptjm-66	68	13	,	,	PUNCT
bptjm-66	68	14	sedation	sedation	NOUN
bptjm-66	68	15	,	,	PUNCT
bptjm-66	68	16	cardiovascular	cardiovascular	ADJ
bptjm-66	68	17	complications	complication	NOUN
bptjm-66	68	18	,	,	PUNCT
bptjm-66	68	19	and	and	CCONJ
bptjm-66	68	20	nausea	nausea	NOUN
bptjm-66	68	21	.	.	PUNCT
bptjm-66	69	1	though	though	SCONJ
bptjm-66	69	2	these	these	DET
bptjm-66	69	3	interactions	interaction	NOUN
bptjm-66	69	4	serve	serve	VERB
bptjm-66	69	5	as	as	ADP
bptjm-66	69	6	promising	promise	VERB
bptjm-66	69	7	pain	pain	NOUN
bptjm-66	69	8	remedies	remedy	NOUN
bptjm-66	69	9	,	,	PUNCT
bptjm-66	69	10	it	it	PRON
bptjm-66	69	11	is	be	AUX
bptjm-66	69	12	important	important	ADJ
bptjm-66	69	13	to	to	PART
bptjm-66	69	14	understand	understand	VERB
bptjm-66	69	15	the	the	DET
bptjm-66	69	16	unintended	unintended	ADJ
bptjm-66	69	17	effects	effect	NOUN
bptjm-66	69	18	they	they	PRON
bptjm-66	69	19	may	may	AUX
bptjm-66	69	20	cause	cause	VERB
bptjm-66	69	21	.	.	PUNCT
bptjm-66	70	1	drugs	drug	NOUN
bptjm-66	70	2	that	that	PRON
bptjm-66	70	3	are	be	AUX
bptjm-66	70	4	capable	capable	ADJ
bptjm-66	70	5	of	of	ADP
bptjm-66	70	6	capitalizing	capitalize	VERB
bptjm-66	70	7	on	on	ADP
bptjm-66	70	8	these	these	DET
bptjm-66	70	9	reception	reception	NOUN
bptjm-66	70	10	functionalities	functionality	NOUN
bptjm-66	70	11	will	will	AUX
bptjm-66	70	12	be	be	AUX
bptjm-66	70	13	reviewed	review	VERB
bptjm-66	70	14	later	later	ADV
bptjm-66	70	15	in	in	ADP
bptjm-66	70	16	the	the	DET
bptjm-66	70	17	document	document	NOUN
bptjm-66	70	18	.	.	PUNCT
bptjm-66	71	1	1.3	1.3	NUM
bptjm-66	71	2	comorbidities	comorbiditie	NOUN
bptjm-66	71	3	pain	pain	NOUN
bptjm-66	71	4	is	be	AUX
bptjm-66	71	5	most	most	ADV
bptjm-66	71	6	commonly	commonly	ADV
bptjm-66	71	7	encountered	encounter	VERB
bptjm-66	71	8	in	in	ADP
bptjm-66	71	9	conjunction	conjunction	NOUN
bptjm-66	71	10	with	with	ADP
bptjm-66	71	11	its	its	PRON
bptjm-66	71	12	comorbidities	comorbiditie	NOUN
bptjm-66	71	13	,	,	PUNCT
bptjm-66	71	14	which	which	PRON
bptjm-66	71	15	is	be	AUX
bptjm-66	71	16	where	where	SCONJ
bptjm-66	71	17	most	most	ADJ
bptjm-66	71	18	of	of	ADP
bptjm-66	71	19	the	the	DET
bptjm-66	71	20	dedicated	dedicated	ADJ
bptjm-66	71	21	research	research	NOUN
bptjm-66	71	22	efforts	effort	NOUN
bptjm-66	71	23	have	have	AUX
bptjm-66	71	24	been	be	AUX
bptjm-66	71	25	focused	focus	VERB
bptjm-66	71	26	.	.	PUNCT
bptjm-66	72	1	neurodegenerative	neurodegenerative	ADJ
bptjm-66	72	2	disorders	disorder	NOUN
bptjm-66	72	3	are	be	AUX
bptjm-66	72	4	normally	normally	ADV
bptjm-66	72	5	associated	associate	VERB
bptjm-66	72	6	with	with	ADP
bptjm-66	72	7	loss	loss	NOUN
bptjm-66	72	8	of	of	ADP
bptjm-66	72	9	coordination	coordination	NOUN
bptjm-66	72	10	,	,	PUNCT
bptjm-66	72	11	memory	memory	NOUN
bptjm-66	72	12	,	,	PUNCT
bptjm-66	72	13	and	and	CCONJ
bptjm-66	72	14	motor	motor	NOUN
bptjm-66	72	15	movements	movement	NOUN
bptjm-66	72	16	.	.	PUNCT
bptjm-66	73	1	understandably	understandably	ADV
bptjm-66	73	2	,	,	PUNCT
bptjm-66	73	3	treatment	treatment	NOUN
bptjm-66	73	4	for	for	ADP
bptjm-66	73	5	these	these	DET
bptjm-66	73	6	neurodegenerative	neurodegenerative	ADJ
bptjm-66	73	7	disorders	disorder	NOUN
bptjm-66	73	8	is	be	AUX
bptjm-66	73	9	focused	focus	VERB
bptjm-66	73	10	on	on	ADP
bptjm-66	73	11	either	either	CCONJ
bptjm-66	73	12	restoring	restore	VERB
bptjm-66	73	13	or	or	CCONJ
bptjm-66	73	14	retarding	retard	VERB
bptjm-66	73	15	the	the	DET
bptjm-66	73	16	progression	progression	NOUN
bptjm-66	73	17	of	of	ADP
bptjm-66	73	18	the	the	DET
bptjm-66	73	19	disorders	disorder	NOUN
bptjm-66	73	20	.	.	PUNCT
bptjm-66	74	1	however	however	ADV
bptjm-66	74	2	,	,	PUNCT
bptjm-66	74	3	patients	patient	NOUN
bptjm-66	74	4	report	report	VERB
bptjm-66	74	5	great	great	ADJ
bptjm-66	74	6	levels	level	NOUN
bptjm-66	74	7	of	of	ADP
bptjm-66	74	8	pain	pain	NOUN
bptjm-66	74	9	;	;	PUNCT
bptjm-66	74	10	thirty	thirty	NUM
bptjm-66	74	11	-	-	PUNCT
bptjm-66	74	12	eight	eight	NUM
bptjm-66	74	13	to	to	PART
bptjm-66	74	14	seventy	seventy	NUM
bptjm-66	74	15	-	-	PUNCT
bptjm-66	74	16	five	five	NUM
bptjm-66	74	17	percent	percent	NOUN
bptjm-66	74	18	in	in	ADP
bptjm-66	74	19	alzheimer	alzheimer	PROPN
bptjm-66	74	20	's	's	PART
bptjm-66	74	21	disease	disease	NOUN
bptjm-66	74	22	and	and	CCONJ
bptjm-66	74	23	berkeley	berkeley	PROPN
bptjm-66	74	24	pharma	pharma	PROPN
bptjm-66	74	25	tech	tech	NOUN
bptjm-66	74	26	journal	journal	NOUN
bptjm-66	74	27	of	of	ADP
bptjm-66	74	28	medicine	medicine	NOUN
bptjm-66	74	29	|	|	ADV
bptjm-66	74	30	5	5	NUM
bptjm-66	74	31	other	other	ADJ
bptjm-66	74	32	dementias	dementia	NOUN
bptjm-66	74	33	,	,	PUNCT
bptjm-66	74	34	forty	forty	NUM
bptjm-66	74	35	to	to	PART
bptjm-66	74	36	eighty	eighty	NUM
bptjm-66	74	37	-	-	PUNCT
bptjm-66	74	38	six	six	NUM
bptjm-66	74	39	percent	percent	NOUN
bptjm-66	74	40	in	in	ADP
bptjm-66	74	41	parkinson	parkinson	NOUN
bptjm-66	74	42	's	's	PART
bptjm-66	74	43	disease	disease	NOUN
bptjm-66	74	44	and	and	CCONJ
bptjm-66	74	45	related	related	ADJ
bptjm-66	74	46	disorders	disorder	NOUN
bptjm-66	74	47	,	,	PUNCT
bptjm-66	74	48	and	and	CCONJ
bptjm-66	74	49	nineteen	nineteen	NUM
bptjm-66	74	50	to	to	PART
bptjm-66	74	51	eighty	eighty	NUM
bptjm-66	74	52	-	-	PUNCT
bptjm-66	74	53	five	five	NUM
bptjm-66	74	54	percent	percent	NOUN
bptjm-66	74	55	in	in	ADP
bptjm-66	74	56	motor	motor	PROPN
bptjm-66	74	57	neuron	neuron	PROPN
bptjm-66	74	58	diseases	disease	NOUN
bptjm-66	74	59	report	report	VERB
bptjm-66	74	60	a	a	DET
bptjm-66	74	61	high	high	ADJ
bptjm-66	74	62	prevalence	prevalence	NOUN
bptjm-66	74	63	of	of	ADP
bptjm-66	74	64	pain13	pain13	NOUN
bptjm-66	74	65	.	.	PUNCT
bptjm-66	75	1	scientists	scientist	NOUN
bptjm-66	75	2	are	be	AUX
bptjm-66	75	3	currently	currently	ADV
bptjm-66	75	4	struggling	struggle	VERB
bptjm-66	75	5	to	to	PART
bptjm-66	75	6	classify	classify	VERB
bptjm-66	75	7	the	the	DET
bptjm-66	75	8	type	type	NOUN
bptjm-66	75	9	of	of	ADP
bptjm-66	75	10	pain	pain	NOUN
bptjm-66	75	11	experienced	experience	VERB
bptjm-66	75	12	by	by	ADP
bptjm-66	75	13	patients	patient	NOUN
bptjm-66	75	14	,	,	PUNCT
bptjm-66	75	15	due	due	ADJ
bptjm-66	75	16	to	to	ADP
bptjm-66	75	17	poor	poor	ADJ
bptjm-66	75	18	diagnostics	diagnostic	NOUN
bptjm-66	75	19	,	,	PUNCT
bptjm-66	75	20	difficulties	difficulty	NOUN
bptjm-66	75	21	in	in	ADP
bptjm-66	75	22	patient	patient	ADJ
bptjm-66	75	23	self	self	NOUN
bptjm-66	75	24	-	-	PUNCT
bptjm-66	75	25	reporting	reporting	NOUN
bptjm-66	75	26	,	,	PUNCT
bptjm-66	75	27	and	and	CCONJ
bptjm-66	75	28	complex	complex	ADJ
bptjm-66	75	29	neuronal	neuronal	ADJ
bptjm-66	75	30	pathways	pathway	NOUN
bptjm-66	75	31	.	.	PUNCT
bptjm-66	76	1	this	this	DET
bptjm-66	76	2	article	article	NOUN
bptjm-66	76	3	will	will	AUX
bptjm-66	76	4	be	be	AUX
bptjm-66	76	5	analyzing	analyze	VERB
bptjm-66	76	6	the	the	DET
bptjm-66	76	7	ongoing	ongoing	ADJ
bptjm-66	76	8	research	research	NOUN
bptjm-66	76	9	on	on	ADP
bptjm-66	76	10	the	the	DET
bptjm-66	76	11	modalities	modality	NOUN
bptjm-66	76	12	of	of	ADP
bptjm-66	76	13	pain	pain	NOUN
bptjm-66	76	14	in	in	ADP
bptjm-66	76	15	parkinson	parkinson	NOUN
bptjm-66	76	16	’s	’s	PART
bptjm-66	76	17	disease	disease	NOUN
bptjm-66	76	18	(	(	PUNCT
bptjm-66	76	19	pd	pd	PROPN
bptjm-66	76	20	)	)	PUNCT
bptjm-66	76	21	,	,	PUNCT
bptjm-66	76	22	the	the	DET
bptjm-66	76	23	most	most	ADV
bptjm-66	76	24	rapidly	rapidly	ADV
bptjm-66	76	25	growing	grow	VERB
bptjm-66	76	26	neurodegenerative	neurodegenerative	ADJ
bptjm-66	76	27	disorder	disorder	NOUN
bptjm-66	76	28	,	,	PUNCT
bptjm-66	76	29	which	which	PRON
bptjm-66	76	30	can	can	AUX
bptjm-66	76	31	be	be	AUX
bptjm-66	76	32	applied	apply	VERB
bptjm-66	76	33	to	to	ADP
bptjm-66	76	34	other	other	ADJ
bptjm-66	76	35	neurodegenerative	neurodegenerative	ADJ
bptjm-66	76	36	disorders	disorder	NOUN
bptjm-66	76	37	.	.	PUNCT
bptjm-66	77	1	in	in	ADP
bptjm-66	77	2	a	a	DET
bptjm-66	77	3	study	study	NOUN
bptjm-66	77	4	conducted	conduct	VERB
bptjm-66	77	5	by	by	ADP
bptjm-66	77	6	cattaneo	cattaneo	PROPN
bptjm-66	77	7	et	et	PROPN
bptjm-66	77	8	al	al	PROPN
bptjm-66	77	9	.	.	PROPN
bptjm-66	77	10	,	,	PUNCT
bptjm-66	77	11	a	a	DET
bptjm-66	77	12	classification	classification	NOUN
bptjm-66	77	13	of	of	ADP
bptjm-66	77	14	pain	pain	NOUN
bptjm-66	77	15	at	at	ADP
bptjm-66	77	16	four	four	NUM
bptjm-66	77	17	levels	level	NOUN
bptjm-66	77	18	was	be	AUX
bptjm-66	77	19	reported	report	VERB
bptjm-66	77	20	.	.	PUNCT
bptjm-66	78	1	the	the	DET
bptjm-66	78	2	first	first	ADJ
bptjm-66	78	3	level	level	NOUN
bptjm-66	78	4	of	of	ADP
bptjm-66	78	5	this	this	DET
bptjm-66	78	6	grouping	group	VERB
bptjm-66	78	7	isolates	isolate	NOUN
bptjm-66	78	8	pain	pain	NOUN
bptjm-66	78	9	into	into	ADP
bptjm-66	78	10	pd	pd	NOUN
bptjm-66	78	11	-	-	PUNCT
bptjm-66	78	12	related	relate	VERB
bptjm-66	78	13	and	and	CCONJ
bptjm-66	78	14	non	non	ADJ
bptjm-66	78	15	-	-	ADJ
bptjm-66	78	16	pd	pd	ADJ
bptjm-66	78	17	-	-	PUNCT
bptjm-66	78	18	related	relate	VERB
bptjm-66	78	19	(	(	PUNCT
bptjm-66	78	20	level	level	NOUN
bptjm-66	78	21	1	1	NUM
bptjm-66	78	22	:	:	PUNCT
bptjm-66	78	23	relationship	relationship	NOUN
bptjm-66	78	24	to	to	ADP
bptjm-66	78	25	pd	pd	PROPN
bptjm-66	78	26	)	)	PUNCT
bptjm-66	78	27	.	.	PUNCT
bptjm-66	79	1	this	this	DET
bptjm-66	79	2	idea	idea	NOUN
bptjm-66	79	3	stems	stem	VERB
bptjm-66	79	4	from	from	ADP
bptjm-66	79	5	correlation	correlation	NOUN
bptjm-66	79	6	,	,	PUNCT
bptjm-66	79	7	as	as	SCONJ
bptjm-66	79	8	many	many	ADJ
bptjm-66	79	9	patients	patient	NOUN
bptjm-66	79	10	with	with	ADP
bptjm-66	79	11	pd	pd	PROPN
bptjm-66	79	12	are	be	AUX
bptjm-66	79	13	elderly	elderly	ADJ
bptjm-66	79	14	.	.	PUNCT
bptjm-66	80	1	in	in	ADP
bptjm-66	80	2	the	the	DET
bptjm-66	80	3	subsequent	subsequent	ADJ
bptjm-66	80	4	level	level	NOUN
bptjm-66	80	5	,	,	PUNCT
bptjm-66	80	6	the	the	DET
bptjm-66	80	7	two	two	NUM
bptjm-66	80	8	aforementioned	aforementioned	ADJ
bptjm-66	80	9	types	type	NOUN
bptjm-66	80	10	of	of	ADP
bptjm-66	80	11	pain	pain	NOUN
bptjm-66	80	12	are	be	AUX
bptjm-66	80	13	classified	classify	VERB
bptjm-66	80	14	as	as	ADP
bptjm-66	80	15	nociceptive	nociceptive	ADJ
bptjm-66	80	16	or	or	CCONJ
bptjm-66	80	17	neuropathic	neuropathic	ADJ
bptjm-66	80	18	;	;	PUNCT
bptjm-66	80	19	if	if	SCONJ
bptjm-66	80	20	it	it	PRON
bptjm-66	80	21	is	be	AUX
bptjm-66	80	22	not	not	PART
bptjm-66	80	23	clear	clear	ADJ
bptjm-66	80	24	which	which	PRON
bptjm-66	80	25	of	of	ADP
bptjm-66	80	26	the	the	DET
bptjm-66	80	27	two	two	NUM
bptjm-66	80	28	classifications	classification	NOUN
bptjm-66	80	29	ought	ought	AUX
bptjm-66	80	30	to	to	PART
bptjm-66	80	31	be	be	AUX
bptjm-66	80	32	picked	pick	VERB
bptjm-66	80	33	,	,	PUNCT
bptjm-66	80	34	pain	pain	NOUN
bptjm-66	80	35	is	be	AUX
bptjm-66	80	36	included	include	VERB
bptjm-66	80	37	in	in	ADP
bptjm-66	80	38	the	the	DET
bptjm-66	80	39	"	"	PUNCT
bptjm-66	80	40	miscellaneous	miscellaneous	ADJ
bptjm-66	80	41	"	"	PUNCT
bptjm-66	80	42	classification	classification	NOUN
bptjm-66	80	43	(	(	PUNCT
bptjm-66	80	44	level	level	NOUN
bptjm-66	80	45	2	2	NUM
bptjm-66	80	46	:	:	PUNCT
bptjm-66	80	47	the	the	DET
bptjm-66	80	48	broader	broad	ADJ
bptjm-66	80	49	categorical	categorical	ADJ
bptjm-66	80	50	system	system	NOUN
bptjm-66	80	51	)	)	PUNCT
bptjm-66	80	52	.	.	PUNCT
bptjm-66	81	1	in	in	ADP
bptjm-66	81	2	the	the	DET
bptjm-66	81	3	third	third	ADJ
bptjm-66	81	4	level	level	NOUN
bptjm-66	81	5	,	,	PUNCT
bptjm-66	81	6	the	the	DET
bptjm-66	81	7	different	different	ADJ
bptjm-66	81	8	types	type	NOUN
bptjm-66	81	9	of	of	ADP
bptjm-66	81	10	pain	pain	NOUN
bptjm-66	81	11	are	be	AUX
bptjm-66	81	12	categorized	categorize	VERB
bptjm-66	81	13	according	accord	VERB
bptjm-66	81	14	to	to	ADP
bptjm-66	81	15	the	the	DET
bptjm-66	81	16	categories	category	NOUN
bptjm-66	81	17	:	:	PUNCT
bptjm-66	81	18	musculoskeletal	musculoskeletal	ADJ
bptjm-66	81	19	,	,	PUNCT
bptjm-66	81	20	visceral	visceral	ADJ
bptjm-66	81	21	,	,	PUNCT
bptjm-66	81	22	cutaneous	cutaneous	ADJ
bptjm-66	81	23	,	,	PUNCT
bptjm-66	81	24	peripheral	peripheral	ADJ
bptjm-66	81	25	,	,	PUNCT
bptjm-66	81	26	or	or	CCONJ
bptjm-66	81	27	central	central	ADJ
bptjm-66	81	28	(	(	PUNCT
bptjm-66	81	29	tier	tier	NOUN
bptjm-66	81	30	3	3	NUM
bptjm-66	81	31	:	:	SYM
bptjm-66	81	32	broad	broad	ADJ
bptjm-66	81	33	type	type	NOUN
bptjm-66	81	34	)	)	PUNCT
bptjm-66	81	35	.	.	PUNCT
bptjm-66	82	1	in	in	ADP
bptjm-66	82	2	the	the	DET
bptjm-66	82	3	last	last	ADJ
bptjm-66	82	4	(	(	PUNCT
bptjm-66	82	5	fourth	fourth	ADJ
bptjm-66	82	6	)	)	PUNCT
bptjm-66	82	7	level	level	NOUN
bptjm-66	82	8	,	,	PUNCT
bptjm-66	82	9	different	different	ADJ
bptjm-66	82	10	aspects	aspect	NOUN
bptjm-66	82	11	from	from	ADP
bptjm-66	82	12	a	a	DET
bptjm-66	82	13	clinical	clinical	ADJ
bptjm-66	82	14	,	,	PUNCT
bptjm-66	82	15	pathogenetic	pathogenetic	ADJ
bptjm-66	82	16	,	,	PUNCT
bptjm-66	82	17	and	and	CCONJ
bptjm-66	82	18	therapeutic	therapeutic	ADJ
bptjm-66	82	19	point	point	NOUN
bptjm-66	82	20	of	of	ADP
bptjm-66	82	21	view	view	NOUN
bptjm-66	82	22	are	be	AUX
bptjm-66	82	23	specified	specify	VERB
bptjm-66	82	24	(	(	PUNCT
bptjm-66	82	25	tier	tier	NOUN
bptjm-66	82	26	4	4	NUM
bptjm-66	82	27	:	:	PUNCT
bptjm-66	82	28	specific	specific	ADJ
bptjm-66	82	29	structures	structure	NOUN
bptjm-66	82	30	and	and	CCONJ
bptjm-66	82	31	pathology	pathology	NOUN
bptjm-66	82	32	)	)	PUNCT
bptjm-66	82	33	.	.	PUNCT
bptjm-66	83	1	another	another	DET
bptjm-66	83	2	important	important	ADJ
bptjm-66	83	3	classification	classification	NOUN
bptjm-66	83	4	method	method	NOUN
bptjm-66	83	5	that	that	PRON
bptjm-66	83	6	is	be	AUX
bptjm-66	83	7	frequently	frequently	ADV
bptjm-66	83	8	used	use	VERB
bptjm-66	83	9	is	be	AUX
bptjm-66	83	10	that	that	PRON
bptjm-66	83	11	of	of	ADP
bptjm-66	83	12	ford	ford	NOUN
bptjm-66	83	13	,	,	PUNCT
bptjm-66	83	14	which	which	PRON
bptjm-66	83	15	considers	consider	VERB
bptjm-66	83	16	five	five	NUM
bptjm-66	83	17	categories	category	NOUN
bptjm-66	83	18	:	:	PUNCT
bptjm-66	83	19	musculoskeletal	musculoskeletal	ADJ
bptjm-66	83	20	,	,	PUNCT
bptjm-66	83	21	dystonic	dystonic	ADJ
bptjm-66	83	22	,	,	PUNCT
bptjm-66	83	23	neuropathic	neuropathic	ADJ
bptjm-66	83	24	/	/	SYM
bptjm-66	83	25	radicular	radicular	ADJ
bptjm-66	83	26	,	,	PUNCT
bptjm-66	83	27	central	central	ADJ
bptjm-66	83	28	/	/	SYM
bptjm-66	83	29	primary	primary	NOUN
bptjm-66	83	30	,	,	PUNCT
bptjm-66	83	31	and	and	CCONJ
bptjm-66	83	32	akathisia14	akathisia14	NOUN
bptjm-66	83	33	.	.	PUNCT
bptjm-66	84	1	a	a	DET
bptjm-66	84	2	significant	significant	ADJ
bptjm-66	84	3	proportion	proportion	NOUN
bptjm-66	84	4	of	of	ADP
bptjm-66	84	5	diabetes	diabetes	NOUN
bptjm-66	84	6	patients	patient	NOUN
bptjm-66	84	7	experience	experience	VERB
bptjm-66	84	8	chronic	chronic	ADJ
bptjm-66	84	9	pain	pain	NOUN
bptjm-66	84	10	.	.	PUNCT
bptjm-66	85	1	musculoskeletal	musculoskeletal	ADJ
bptjm-66	85	2	pain	pain	NOUN
bptjm-66	85	3	and	and	CCONJ
bptjm-66	85	4	neuropathy	neuropathy	ADJ
bptjm-66	85	5	are	be	AUX
bptjm-66	85	6	the	the	DET
bptjm-66	85	7	common	common	ADJ
bptjm-66	85	8	symptoms	symptom	NOUN
bptjm-66	85	9	of	of	ADP
bptjm-66	85	10	pain	pain	NOUN
bptjm-66	85	11	,	,	PUNCT
bptjm-66	85	12	stemming	stem	VERB
bptjm-66	85	13	from	from	ADP
bptjm-66	85	14	alterations	alteration	NOUN
bptjm-66	85	15	in	in	ADP
bptjm-66	85	16	the	the	DET
bptjm-66	85	17	structural	structural	ADJ
bptjm-66	85	18	matrix	matrix	NOUN
bptjm-66	85	19	and	and	CCONJ
bptjm-66	85	20	mechanical	mechanical	ADJ
bptjm-66	85	21	properties	property	NOUN
bptjm-66	85	22	of	of	ADP
bptjm-66	85	23	periarticular	periarticular	ADJ
bptjm-66	85	24	connective	connective	ADJ
bptjm-66	85	25	tissues	tissue	NOUN
bptjm-66	85	26	,	,	PUNCT
bptjm-66	85	27	owing	owe	VERB
bptjm-66	85	28	to	to	ADP
bptjm-66	85	29	an	an	DET
bptjm-66	85	30	unusual	unusual	ADJ
bptjm-66	85	31	deposition	deposition	NOUN
bptjm-66	85	32	of	of	ADP
bptjm-66	85	33	collagen15	collagen15	NOUN
bptjm-66	85	34	.	.	PUNCT
bptjm-66	86	1	these	these	DET
bptjm-66	86	2	defects	defect	NOUN
bptjm-66	86	3	further	further	ADJ
bptjm-66	86	4	lead	lead	NOUN
bptjm-66	86	5	to	to	ADP
bptjm-66	86	6	rheumatic	rheumatic	ADJ
bptjm-66	86	7	problems	problem	NOUN
bptjm-66	86	8	such	such	ADJ
bptjm-66	86	9	as	as	ADP
bptjm-66	86	10	the	the	DET
bptjm-66	86	11	reduced	reduced	ADJ
bptjm-66	86	12	mobility	mobility	NOUN
bptjm-66	86	13	of	of	ADP
bptjm-66	86	14	joints	joint	NOUN
bptjm-66	86	15	,	,	PUNCT
bptjm-66	86	16	stiff	stiff	ADJ
bptjm-66	86	17	hand	hand	NOUN
bptjm-66	86	18	and	and	CCONJ
bptjm-66	86	19	carpal	carpal	NOUN
bptjm-66	86	20	tunnel	tunnel	NOUN
bptjm-66	86	21	syndromes	syndrome	NOUN
bptjm-66	86	22	,	,	PUNCT
bptjm-66	86	23	shoulder	shoulder	NOUN
bptjm-66	86	24	capsulitis	capsulitis	NOUN
bptjm-66	86	25	,	,	PUNCT
bptjm-66	86	26	and	and	CCONJ
bptjm-66	86	27	tenosynovitis16	tenosynovitis16	NOUN
bptjm-66	86	28	.	.	PUNCT
bptjm-66	87	1	these	these	DET
bptjm-66	87	2	trends	trend	NOUN
bptjm-66	87	3	may	may	AUX
bptjm-66	87	4	reflect	reflect	VERB
bptjm-66	87	5	correlation	correlation	NOUN
bptjm-66	87	6	rather	rather	ADV
bptjm-66	87	7	than	than	ADP
bptjm-66	87	8	causation	causation	NOUN
bptjm-66	87	9	.	.	PUNCT
bptjm-66	88	1	but	but	CCONJ
bptjm-66	88	2	according	accord	VERB
bptjm-66	88	3	to	to	ADP
bptjm-66	88	4	a	a	DET
bptjm-66	88	5	study	study	NOUN
bptjm-66	88	6	sampling	sample	VERB
bptjm-66	88	7	populations	population	NOUN
bptjm-66	88	8	with	with	ADP
bptjm-66	88	9	nondiabetics	nondiabetic	NOUN
bptjm-66	88	10	,	,	PUNCT
bptjm-66	88	11	diabetics	diabetic	NOUN
bptjm-66	88	12	,	,	PUNCT
bptjm-66	88	13	and	and	CCONJ
bptjm-66	88	14	prediabetics	prediabetic	NOUN
bptjm-66	88	15	,	,	PUNCT
bptjm-66	88	16	the	the	DET
bptjm-66	88	17	results	result	NOUN
bptjm-66	88	18	showed	show	VERB
bptjm-66	88	19	that	that	SCONJ
bptjm-66	88	20	,	,	PUNCT
bptjm-66	88	21	compared	compare	VERB
bptjm-66	88	22	to	to	ADP
bptjm-66	88	23	prediabetic	prediabetic	ADJ
bptjm-66	88	24	and	and	CCONJ
bptjm-66	88	25	nondiabetic	nondiabetic	ADJ
bptjm-66	88	26	individuals	individual	NOUN
bptjm-66	88	27	,	,	PUNCT
bptjm-66	88	28	diabetic	diabetic	ADJ
bptjm-66	88	29	subjects	subject	NOUN
bptjm-66	88	30	have	have	VERB
bptjm-66	88	31	a	a	DET
bptjm-66	88	32	higher	high	ADJ
bptjm-66	88	33	prevalence	prevalence	NOUN
bptjm-66	88	34	of	of	ADP
bptjm-66	88	35	lower	low	ADJ
bptjm-66	88	36	limb	limb	NOUN
bptjm-66	88	37	pain	pain	NOUN
bptjm-66	88	38	(	(	PUNCT
bptjm-66	88	39	11.1	11.1	NUM
bptjm-66	88	40	%	%	NOUN
bptjm-66	88	41	)	)	PUNCT
bptjm-66	88	42	,	,	PUNCT
bptjm-66	88	43	back	back	ADJ
bptjm-66	88	44	pain	pain	NOUN
bptjm-66	88	45	(	(	PUNCT
bptjm-66	88	46	8.9	8.9	NUM
bptjm-66	88	47	%	%	NOUN
bptjm-66	88	48	)	)	PUNCT
bptjm-66	88	49	,	,	PUNCT
bptjm-66	88	50	abdominal	abdominal	ADJ
bptjm-66	88	51	pain	pain	NOUN
bptjm-66	88	52	(	(	PUNCT
bptjm-66	88	53	6.7	6.7	NUM
bptjm-66	88	54	%	%	NOUN
bptjm-66	88	55	)	)	PUNCT
bptjm-66	88	56	,	,	PUNCT
bptjm-66	88	57	and	and	CCONJ
bptjm-66	88	58	neck	neck	NOUN
bptjm-66	88	59	pain	pain	NOUN
bptjm-66	88	60	(	(	PUNCT
bptjm-66	88	61	4.4	4.4	NUM
bptjm-66	88	62	%	%	NOUN
bptjm-66	88	63	)	)	PUNCT
bptjm-66	88	64	.	.	PUNCT
bptjm-66	89	1	a	a	DET
bptjm-66	89	2	chi	chi	ADJ
bptjm-66	89	3	-	-	PUNCT
bptjm-66	89	4	squared	square	VERB
bptjm-66	89	5	test	test	NOUN
bptjm-66	89	6	confirmed	confirm	VERB
bptjm-66	89	7	that	that	SCONJ
bptjm-66	89	8	diabetic	diabetic	ADJ
bptjm-66	89	9	and	and	CCONJ
bptjm-66	89	10	prediabetic	prediabetic	ADJ
bptjm-66	89	11	patients	patient	NOUN
bptjm-66	89	12	had	have	VERB
bptjm-66	89	13	a	a	DET
bptjm-66	89	14	significantly	significantly	ADV
bptjm-66	89	15	higher	high	ADJ
bptjm-66	89	16	berkeley	berkeley	PROPN
bptjm-66	89	17	pharma	pharma	PROPN
bptjm-66	89	18	tech	tech	NOUN
bptjm-66	89	19	journal	journal	NOUN
bptjm-66	89	20	of	of	ADP
bptjm-66	89	21	medicine	medicine	NOUN
bptjm-66	89	22	|	|	ADV
bptjm-66	89	23	6	6	NUM
bptjm-66	89	24	prevalence	prevalence	NOUN
bptjm-66	89	25	of	of	ADP
bptjm-66	89	26	chronic	chronic	ADJ
bptjm-66	89	27	pain17	pain17	NOUN
bptjm-66	89	28	.	.	PUNCT
bptjm-66	90	1	if	if	SCONJ
bptjm-66	90	2	this	this	DET
bptjm-66	90	3	problem	problem	NOUN
bptjm-66	90	4	is	be	AUX
bptjm-66	90	5	not	not	PART
bptjm-66	90	6	properly	properly	ADV
bptjm-66	90	7	dealt	deal	VERB
bptjm-66	90	8	with	with	ADP
bptjm-66	90	9	,	,	PUNCT
bptjm-66	90	10	chronic	chronic	ADJ
bptjm-66	90	11	pain	pain	NOUN
bptjm-66	90	12	may	may	AUX
bptjm-66	90	13	spiral	spiral	VERB
bptjm-66	90	14	into	into	ADP
bptjm-66	90	15	larger	large	ADJ
bptjm-66	90	16	health	health	NOUN
bptjm-66	90	17	problems	problem	NOUN
bptjm-66	90	18	,	,	PUNCT
bptjm-66	90	19	causing	cause	VERB
bptjm-66	90	20	a	a	DET
bptjm-66	90	21	greater	great	ADJ
bptjm-66	90	22	disruption	disruption	NOUN
bptjm-66	90	23	in	in	ADP
bptjm-66	90	24	the	the	DET
bptjm-66	90	25	lives	life	NOUN
bptjm-66	90	26	of	of	ADP
bptjm-66	90	27	many	many	ADJ
bptjm-66	90	28	.	.	PUNCT
bptjm-66	91	1	cancer	cancer	NOUN
bptjm-66	91	2	-	-	PUNCT
bptjm-66	91	3	related	relate	VERB
bptjm-66	91	4	chronic	chronic	ADJ
bptjm-66	91	5	pain	pain	NOUN
bptjm-66	91	6	affects	affect	VERB
bptjm-66	91	7	about	about	ADV
bptjm-66	91	8	40	40	NUM
bptjm-66	91	9	-	-	SYM
bptjm-66	91	10	70	70	NUM
bptjm-66	91	11	%	%	NOUN
bptjm-66	91	12	of	of	ADP
bptjm-66	91	13	patients	patient	NOUN
bptjm-66	91	14	with	with	ADP
bptjm-66	91	15	cancer	cancer	NOUN
bptjm-66	91	16	diagnostics	diagnostic	NOUN
bptjm-66	91	17	and	and	CCONJ
bptjm-66	91	18	33	33	NUM
bptjm-66	91	19	-	-	SYM
bptjm-66	91	20	40	40	NUM
bptjm-66	91	21	%	%	NOUN
bptjm-66	91	22	of	of	ADP
bptjm-66	91	23	long	long	ADJ
bptjm-66	91	24	-	-	PUNCT
bptjm-66	91	25	term	term	NOUN
bptjm-66	91	26	cancer	cancer	NOUN
bptjm-66	91	27	survivors	survivor	NOUN
bptjm-66	91	28	suffer	suffer	VERB
bptjm-66	91	29	from	from	ADP
bptjm-66	91	30	chronic	chronic	ADJ
bptjm-66	91	31	pain18	pain18	NOUN
bptjm-66	91	32	.	.	PUNCT
bptjm-66	92	1	there	there	PRON
bptjm-66	92	2	exist	exist	VERB
bptjm-66	92	3	numerous	numerous	ADJ
bptjm-66	92	4	sources	source	NOUN
bptjm-66	92	5	of	of	ADP
bptjm-66	92	6	pain	pain	NOUN
bptjm-66	92	7	,	,	PUNCT
bptjm-66	92	8	including	include	VERB
bptjm-66	92	9	the	the	DET
bptjm-66	92	10	tumor	tumor	NOUN
bptjm-66	92	11	itself	itself	PRON
bptjm-66	92	12	,	,	PUNCT
bptjm-66	92	13	chemotherapeutic	chemotherapeutic	ADJ
bptjm-66	92	14	agents	agent	NOUN
bptjm-66	92	15	,	,	PUNCT
bptjm-66	92	16	and	and	CCONJ
bptjm-66	92	17	surgical	surgical	ADJ
bptjm-66	92	18	interventions	intervention	NOUN
bptjm-66	92	19	.	.	PUNCT
bptjm-66	93	1	all	all	PRON
bptjm-66	93	2	of	of	ADP
bptjm-66	93	3	these	these	DET
bptjm-66	93	4	factors	factor	NOUN
bptjm-66	93	5	can	can	AUX
bptjm-66	93	6	not	not	PART
bptjm-66	93	7	only	only	ADV
bptjm-66	93	8	cause	cause	VERB
bptjm-66	93	9	physical	physical	ADJ
bptjm-66	93	10	pain	pain	NOUN
bptjm-66	93	11	,	,	PUNCT
bptjm-66	93	12	but	but	CCONJ
bptjm-66	93	13	also	also	ADV
bptjm-66	93	14	significant	significant	ADJ
bptjm-66	93	15	psychological	psychological	ADJ
bptjm-66	93	16	pain	pain	NOUN
bptjm-66	93	17	.	.	PUNCT
bptjm-66	94	1	delivery	delivery	NOUN
bptjm-66	94	2	of	of	ADP
bptjm-66	94	3	therapeutics	therapeutic	NOUN
bptjm-66	94	4	is	be	AUX
bptjm-66	94	5	currently	currently	ADV
bptjm-66	94	6	a	a	DET
bptjm-66	94	7	hot	hot	ADJ
bptjm-66	94	8	area	area	NOUN
bptjm-66	94	9	of	of	ADP
bptjm-66	94	10	research	research	NOUN
bptjm-66	94	11	in	in	ADP
bptjm-66	94	12	cancer	cancer	NOUN
bptjm-66	94	13	research	research	NOUN
bptjm-66	94	14	and	and	CCONJ
bptjm-66	94	15	will	will	AUX
bptjm-66	94	16	be	be	AUX
bptjm-66	94	17	covered	cover	VERB
bptjm-66	94	18	in	in	ADP
bptjm-66	94	19	this	this	DET
bptjm-66	94	20	article	article	NOUN
bptjm-66	94	21	.	.	PUNCT
bptjm-66	95	1	2	2	X
bptjm-66	95	2	.	.	NUM
bptjm-66	95	3	previous	previous	ADJ
bptjm-66	95	4	treatment	treatment	NOUN
bptjm-66	95	5	modalities	modality	NOUN
bptjm-66	95	6	2.1	2.1	NUM
bptjm-66	95	7	nonopioid	nonopioid	NOUN
bptjm-66	95	8	drugs	drug	NOUN
bptjm-66	95	9	popular	popular	ADJ
bptjm-66	95	10	pharmaceutical	pharmaceutical	ADJ
bptjm-66	95	11	drugs	drug	NOUN
bptjm-66	95	12	fall	fall	VERB
bptjm-66	95	13	into	into	ADP
bptjm-66	95	14	three	three	NUM
bptjm-66	95	15	primary	primary	ADJ
bptjm-66	95	16	categories	category	NOUN
bptjm-66	95	17	:	:	PUNCT
bptjm-66	95	18	nonsteroidal	nonsteroidal	NOUN
bptjm-66	95	19	anti	anti	ADJ
bptjm-66	95	20	-	-	ADJ
bptjm-66	95	21	inflammatory	inflammatory	ADJ
bptjm-66	95	22	drugs	drug	NOUN
bptjm-66	95	23	(	(	PUNCT
bptjm-66	95	24	nsaids	nsaid	NOUN
bptjm-66	95	25	)	)	PUNCT
bptjm-66	95	26	,	,	PUNCT
bptjm-66	95	27	acetaminophen	acetaminophen	NOUN
bptjm-66	95	28	,	,	PUNCT
bptjm-66	95	29	and	and	CCONJ
bptjm-66	95	30	adjuvant	adjuvant	ADJ
bptjm-66	95	31	analgesics	analgesic	NOUN
bptjm-66	95	32	.	.	PUNCT
bptjm-66	96	1	nsaids	nsaid	NOUN
bptjm-66	96	2	work	work	VERB
bptjm-66	96	3	primarily	primarily	ADV
bptjm-66	96	4	by	by	ADP
bptjm-66	96	5	inhibiting	inhibit	VERB
bptjm-66	96	6	the	the	DET
bptjm-66	96	7	activity	activity	NOUN
bptjm-66	96	8	of	of	ADP
bptjm-66	96	9	the	the	DET
bptjm-66	96	10	cox-1	cox-1	ADV
bptjm-66	96	11	and	and	CCONJ
bptjm-66	96	12	cox-2	cox-2	ADJ
bptjm-66	96	13	enzymes	enzyme	NOUN
bptjm-66	96	14	,	,	PUNCT
bptjm-66	96	15	which	which	PRON
bptjm-66	96	16	are	be	AUX
bptjm-66	96	17	subsets	subset	NOUN
bptjm-66	96	18	of	of	ADP
bptjm-66	96	19	the	the	DET
bptjm-66	96	20	calcium	calcium	NOUN
bptjm-66	96	21	-	-	PUNCT
bptjm-66	96	22	dependent	dependent	ADJ
bptjm-66	96	23	kinases	kinase	NOUN
bptjm-66	96	24	mentioned	mention	VERB
bptjm-66	96	25	earlier19	earlier19	ADV
bptjm-66	96	26	.	.	PUNCT
bptjm-66	97	1	this	this	DET
bptjm-66	97	2	inhibition	inhibition	NOUN
bptjm-66	97	3	leads	lead	VERB
bptjm-66	97	4	to	to	ADP
bptjm-66	97	5	reduced	reduce	VERB
bptjm-66	97	6	prostaglandin	prostaglandin	NOUN
bptjm-66	97	7	expression	expression	NOUN
bptjm-66	97	8	,	,	PUNCT
bptjm-66	97	9	resulting	result	VERB
bptjm-66	97	10	in	in	ADP
bptjm-66	97	11	analgesic	analgesic	ADJ
bptjm-66	97	12	effects	effect	NOUN
bptjm-66	97	13	and	and	CCONJ
bptjm-66	97	14	decreased	decrease	VERB
bptjm-66	97	15	inflammation	inflammation	NOUN
bptjm-66	97	16	.	.	PUNCT
bptjm-66	98	1	however	however	ADV
bptjm-66	98	2	,	,	PUNCT
bptjm-66	98	3	a	a	DET
bptjm-66	98	4	significant	significant	ADJ
bptjm-66	98	5	drawback	drawback	NOUN
bptjm-66	98	6	of	of	ADP
bptjm-66	98	7	nsaids	nsaid	NOUN
bptjm-66	98	8	is	be	AUX
bptjm-66	98	9	the	the	DET
bptjm-66	98	10	increased	increase	VERB
bptjm-66	98	11	risk	risk	NOUN
bptjm-66	98	12	of	of	ADP
bptjm-66	98	13	cardiovascular	cardiovascular	ADJ
bptjm-66	98	14	issues	issue	NOUN
bptjm-66	98	15	and	and	CCONJ
bptjm-66	98	16	gastrointestinal	gastrointestinal	ADJ
bptjm-66	98	17	complications	complication	NOUN
bptjm-66	98	18	.	.	PUNCT
bptjm-66	99	1	nsaids	nsaid	NOUN
bptjm-66	99	2	are	be	AUX
bptjm-66	99	3	responsible	responsible	ADJ
bptjm-66	99	4	for	for	ADP
bptjm-66	99	5	30	30	NUM
bptjm-66	99	6	%	%	NOUN
bptjm-66	99	7	of	of	ADP
bptjm-66	99	8	adverse	adverse	ADJ
bptjm-66	99	9	drug	drug	NOUN
bptjm-66	99	10	reactions	reaction	NOUN
bptjm-66	99	11	such	such	ADJ
bptjm-66	99	12	as	as	ADP
bptjm-66	99	13	strokes	stroke	NOUN
bptjm-66	99	14	,	,	PUNCT
bptjm-66	99	15	heart	heart	NOUN
bptjm-66	99	16	attacks	attack	NOUN
bptjm-66	99	17	,	,	PUNCT
bptjm-66	99	18	renal	renal	ADJ
bptjm-66	99	19	damage	damage	NOUN
bptjm-66	99	20	,	,	PUNCT
bptjm-66	99	21	and	and	CCONJ
bptjm-66	99	22	bleeding	bleeding	NOUN
bptjm-66	99	23	.	.	PUNCT
bptjm-66	100	1	common	common	ADJ
bptjm-66	100	2	examples	example	NOUN
bptjm-66	100	3	of	of	ADP
bptjm-66	100	4	nsaids	nsaid	NOUN
bptjm-66	100	5	include	include	VERB
bptjm-66	100	6	aspirin	aspirin	NOUN
bptjm-66	100	7	,	,	PUNCT
bptjm-66	100	8	ibuprofen	ibuprofen	NOUN
bptjm-66	100	9	,	,	PUNCT
bptjm-66	100	10	and	and	CCONJ
bptjm-66	100	11	naproxen	naproxen	PROPN
bptjm-66	100	12	.	.	PUNCT
bptjm-66	101	1	the	the	DET
bptjm-66	101	2	other	other	ADJ
bptjm-66	101	3	common	common	ADJ
bptjm-66	101	4	drug	drug	NOUN
bptjm-66	101	5	,	,	PUNCT
bptjm-66	101	6	acetaminophen	acetaminophen	NOUN
bptjm-66	101	7	,	,	PUNCT
bptjm-66	101	8	commonly	commonly	ADV
bptjm-66	101	9	recognized	recognize	VERB
bptjm-66	101	10	as	as	ADP
bptjm-66	101	11	tylenol	tylenol	NOUN
bptjm-66	101	12	,	,	PUNCT
bptjm-66	101	13	operates	operate	VERB
bptjm-66	101	14	similarly	similarly	ADV
bptjm-66	101	15	to	to	ADP
bptjm-66	101	16	nsaids	nsaid	NOUN
bptjm-66	101	17	.	.	PUNCT
bptjm-66	102	1	however	however	ADV
bptjm-66	102	2	,	,	PUNCT
bptjm-66	102	3	unlike	unlike	ADP
bptjm-66	102	4	nsaids	nsaid	NOUN
bptjm-66	102	5	,	,	PUNCT
bptjm-66	102	6	it	it	PRON
bptjm-66	102	7	does	do	AUX
bptjm-66	102	8	not	not	PART
bptjm-66	102	9	interfere	interfere	VERB
bptjm-66	102	10	with	with	ADP
bptjm-66	102	11	the	the	DET
bptjm-66	102	12	cox	cox	PROPN
bptjm-66	102	13	pathway	pathway	NOUN
bptjm-66	102	14	in	in	ADP
bptjm-66	102	15	the	the	DET
bptjm-66	102	16	peripheral	peripheral	ADJ
bptjm-66	102	17	nervous	nervous	ADJ
bptjm-66	102	18	system	system	NOUN
bptjm-66	102	19	;	;	PUNCT
bptjm-66	102	20	instead	instead	ADV
bptjm-66	102	21	,	,	PUNCT
bptjm-66	102	22	its	its	PRON
bptjm-66	102	23	effects	effect	NOUN
bptjm-66	102	24	are	be	AUX
bptjm-66	102	25	limited	limit	VERB
bptjm-66	102	26	to	to	ADP
bptjm-66	102	27	the	the	DET
bptjm-66	102	28	central	central	ADJ
bptjm-66	102	29	nervous	nervous	ADJ
bptjm-66	102	30	system	system	NOUN
bptjm-66	102	31	.	.	PUNCT
bptjm-66	103	1	as	as	ADP
bptjm-66	103	2	a	a	DET
bptjm-66	103	3	result	result	NOUN
bptjm-66	103	4	,	,	PUNCT
bptjm-66	103	5	tylenol	tylenol	NOUN
bptjm-66	103	6	effectively	effectively	ADV
bptjm-66	103	7	alleviates	alleviate	VERB
bptjm-66	103	8	pain	pain	NOUN
bptjm-66	103	9	perception	perception	NOUN
bptjm-66	103	10	and	and	CCONJ
bptjm-66	103	11	reduces	reduce	VERB
bptjm-66	103	12	fever	fever	NOUN
bptjm-66	103	13	but	but	CCONJ
bptjm-66	103	14	lacks	lack	VERB
bptjm-66	103	15	efficacy	efficacy	NOUN
bptjm-66	103	16	in	in	ADP
bptjm-66	103	17	diminishing	diminish	VERB
bptjm-66	103	18	inflammation	inflammation	NOUN
bptjm-66	103	19	.	.	PUNCT
bptjm-66	104	1	when	when	SCONJ
bptjm-66	104	2	used	use	VERB
bptjm-66	104	3	in	in	ADP
bptjm-66	104	4	appropriate	appropriate	ADJ
bptjm-66	104	5	doses	dose	NOUN
bptjm-66	104	6	,	,	PUNCT
bptjm-66	104	7	tylenol	tylenol	NOUN
bptjm-66	104	8	is	be	AUX
bptjm-66	104	9	generally	generally	ADV
bptjm-66	104	10	considered	consider	VERB
bptjm-66	104	11	safe	safe	ADJ
bptjm-66	104	12	.	.	PUNCT
bptjm-66	105	1	however	however	ADV
bptjm-66	105	2	,	,	PUNCT
bptjm-66	105	3	prolonged	prolonged	ADJ
bptjm-66	105	4	or	or	CCONJ
bptjm-66	105	5	excessive	excessive	ADJ
bptjm-66	105	6	usage	usage	NOUN
bptjm-66	105	7	can	can	AUX
bptjm-66	105	8	lead	lead	VERB
bptjm-66	105	9	to	to	ADP
bptjm-66	105	10	liver	liver	NOUN
bptjm-66	105	11	damage	damage	NOUN
bptjm-66	105	12	,	,	PUNCT
bptjm-66	105	13	occasionally	occasionally	ADV
bptjm-66	105	14	fatal	fatal	ADJ
bptjm-66	105	15	.	.	PUNCT
bptjm-66	106	1	adjuvant	adjuvant	ADJ
bptjm-66	106	2	analgesics	analgesic	NOUN
bptjm-66	106	3	include	include	VERB
bptjm-66	106	4	most	most	ADJ
bptjm-66	106	5	non	non	ADJ
bptjm-66	106	6	-	-	ADJ
bptjm-66	106	7	opioid	opioid	ADJ
bptjm-66	106	8	drugs	drug	NOUN
bptjm-66	106	9	that	that	PRON
bptjm-66	106	10	are	be	AUX
bptjm-66	106	11	not	not	PART
bptjm-66	106	12	classified	classify	VERB
bptjm-66	106	13	as	as	ADP
bptjm-66	106	14	acetaminophen	acetaminophen	NOUN
bptjm-66	106	15	and	and	CCONJ
bptjm-66	106	16	nsaids	nsaid	NOUN
bptjm-66	106	17	.	.	PUNCT
bptjm-66	107	1	adjuvant	adjuvant	ADJ
bptjm-66	107	2	analgesics	analgesic	NOUN
bptjm-66	107	3	refer	refer	VERB
bptjm-66	107	4	to	to	ADP
bptjm-66	107	5	medicine	medicine	NOUN
bptjm-66	107	6	that	that	SCONJ
bptjm-66	107	7	berkeley	berkeley	PROPN
bptjm-66	107	8	pharma	pharma	PROPN
bptjm-66	107	9	tech	tech	NOUN
bptjm-66	107	10	journal	journal	NOUN
bptjm-66	107	11	of	of	ADP
bptjm-66	107	12	medicine	medicine	NOUN
bptjm-66	107	13	|	|	ADV
bptjm-66	107	14	7	7	NUM
bptjm-66	107	15	was	be	AUX
bptjm-66	107	16	originally	originally	ADV
bptjm-66	107	17	engineered	engineer	VERB
bptjm-66	107	18	for	for	ADP
bptjm-66	107	19	purposes	purpose	NOUN
bptjm-66	107	20	other	other	ADJ
bptjm-66	107	21	than	than	ADP
bptjm-66	107	22	pain	pain	NOUN
bptjm-66	107	23	management	management	NOUN
bptjm-66	107	24	;	;	PUNCT
bptjm-66	107	25	popular	popular	ADJ
bptjm-66	107	26	agents	agent	NOUN
bptjm-66	107	27	include	include	VERB
bptjm-66	107	28	antidepressants	antidepressant	NOUN
bptjm-66	107	29	and	and	CCONJ
bptjm-66	107	30	anticonvulsants	anticonvulsant	NOUN
bptjm-66	107	31	.	.	PUNCT
bptjm-66	108	1	because	because	SCONJ
bptjm-66	108	2	of	of	ADP
bptjm-66	108	3	the	the	DET
bptjm-66	108	4	nervous	nervous	ADJ
bptjm-66	108	5	system	system	NOUN
bptjm-66	108	6	’s	’s	PART
bptjm-66	108	7	interconnectedness	interconnectedness	NOUN
bptjm-66	108	8	,	,	PUNCT
bptjm-66	108	9	drugs	drug	NOUN
bptjm-66	108	10	that	that	PRON
bptjm-66	108	11	operate	operate	VERB
bptjm-66	108	12	in	in	ADP
bptjm-66	108	13	the	the	DET
bptjm-66	108	14	nervous	nervous	ADJ
bptjm-66	108	15	system	system	NOUN
bptjm-66	108	16	for	for	ADP
bptjm-66	108	17	conditions	condition	NOUN
bptjm-66	108	18	such	such	ADJ
bptjm-66	108	19	as	as	ADP
bptjm-66	108	20	depression	depression	NOUN
bptjm-66	108	21	or	or	CCONJ
bptjm-66	108	22	convulsions	convulsion	NOUN
bptjm-66	108	23	affect	affect	VERB
bptjm-66	108	24	pathways	pathway	NOUN
bptjm-66	108	25	involved	involve	VERB
bptjm-66	108	26	in	in	ADP
bptjm-66	108	27	pain	pain	NOUN
bptjm-66	108	28	reception	reception	NOUN
bptjm-66	108	29	.	.	PUNCT
bptjm-66	109	1	specifically	specifically	ADV
bptjm-66	109	2	,	,	PUNCT
bptjm-66	109	3	their	their	PRON
bptjm-66	109	4	effects	effect	NOUN
bptjm-66	109	5	on	on	ADP
bptjm-66	109	6	the	the	DET
bptjm-66	109	7	spinal	spinal	ADJ
bptjm-66	109	8	cord	cord	NOUN
bptjm-66	109	9	and	and	CCONJ
bptjm-66	109	10	dorsal	dorsal	NOUN
bptjm-66	109	11	horn	horn	NOUN
bptjm-66	109	12	overlap	overlap	NOUN
bptjm-66	109	13	.	.	PUNCT
bptjm-66	110	1	antidepressants	antidepressant	NOUN
bptjm-66	110	2	suppress	suppress	VERB
bptjm-66	110	3	neuropathic	neuropathic	ADJ
bptjm-66	110	4	pain	pain	NOUN
bptjm-66	110	5	by	by	ADP
bptjm-66	110	6	enhancing	enhance	VERB
bptjm-66	110	7	noradrenaline	noradrenaline	ADJ
bptjm-66	110	8	influx	influx	NOUN
bptjm-66	110	9	in	in	ADP
bptjm-66	110	10	the	the	DET
bptjm-66	110	11	spinal	spinal	ADJ
bptjm-66	110	12	cord20	cord20	NOUN
bptjm-66	110	13	.	.	PUNCT
bptjm-66	111	1	this	this	DET
bptjm-66	111	2	neurotransmitter	neurotransmitter	NOUN
bptjm-66	111	3	binds	bind	VERB
bptjm-66	111	4	to	to	ADP
bptjm-66	111	5	α2	α2	ADJ
bptjm-66	111	6	-	-	PUNCT
bptjm-66	111	7	adrenergic	adrenergic	NOUN
bptjm-66	111	8	receptors	receptor	NOUN
bptjm-66	111	9	,	,	PUNCT
bptjm-66	111	10	initiating	initiate	VERB
bptjm-66	111	11	downstream	downstream	ADJ
bptjm-66	111	12	signaling	signal	VERB
bptjm-66	111	13	cascades	cascade	NOUN
bptjm-66	111	14	that	that	PRON
bptjm-66	111	15	inhibit	inhibit	VERB
bptjm-66	111	16	calcium	calcium	NOUN
bptjm-66	111	17	channel	channel	NOUN
bptjm-66	111	18	activity	activity	NOUN
bptjm-66	111	19	in	in	ADP
bptjm-66	111	20	the	the	DET
bptjm-66	111	21	dorsal	dorsal	NOUN
bptjm-66	111	22	horn	horn	NOUN
bptjm-66	111	23	and	and	CCONJ
bptjm-66	111	24	dampen	dampen	VERB
bptjm-66	111	25	neurotransmitter	neurotransmitter	NOUN
bptjm-66	111	26	transmission	transmission	NOUN
bptjm-66	111	27	,	,	PUNCT
bptjm-66	111	28	thereby	thereby	ADV
bptjm-66	111	29	inhibiting	inhibit	VERB
bptjm-66	111	30	hyperalgesia	hyperalgesia	NOUN
bptjm-66	111	31	and	and	CCONJ
bptjm-66	111	32	allodynia	allodynia	ADJ
bptjm-66	111	33	.	.	PUNCT
bptjm-66	112	1	additionally	additionally	ADV
bptjm-66	112	2	,	,	PUNCT
bptjm-66	112	3	antidepressants	antidepressant	NOUN
bptjm-66	112	4	hold	hold	VERB
bptjm-66	112	5	therapeutic	therapeutic	ADJ
bptjm-66	112	6	effects	effect	NOUN
bptjm-66	112	7	on	on	ADP
bptjm-66	112	8	the	the	DET
bptjm-66	112	9	locus	locus	NOUN
bptjm-66	112	10	coeruleus	coeruleus	NOUN
bptjm-66	112	11	,	,	PUNCT
bptjm-66	112	12	a	a	DET
bptjm-66	112	13	brain	brain	NOUN
bptjm-66	112	14	region	region	NOUN
bptjm-66	112	15	rich	rich	ADJ
bptjm-66	112	16	in	in	ADP
bptjm-66	112	17	noradrenergic	noradrenergic	ADJ
bptjm-66	112	18	nerve	nerve	NOUN
bptjm-66	112	19	cells	cell	NOUN
bptjm-66	112	20	.	.	PUNCT
bptjm-66	113	1	following	follow	VERB
bptjm-66	113	2	injury	injury	NOUN
bptjm-66	113	3	,	,	PUNCT
bptjm-66	113	4	the	the	DET
bptjm-66	113	5	locus	locus	NOUN
bptjm-66	113	6	coeruleus	coeruleus	NOUN
bptjm-66	113	7	releases	release	VERB
bptjm-66	113	8	noradrenaline	noradrenaline	ADJ
bptjm-66	113	9	in	in	ADP
bptjm-66	113	10	response	response	NOUN
bptjm-66	113	11	to	to	ADP
bptjm-66	113	12	noxious	noxious	ADJ
bptjm-66	113	13	stimuli	stimulus	NOUN
bptjm-66	113	14	,	,	PUNCT
bptjm-66	113	15	contributing	contribute	VERB
bptjm-66	113	16	to	to	ADP
bptjm-66	113	17	nociceptive	nociceptive	ADJ
bptjm-66	113	18	analgesia	analgesia	NOUN
bptjm-66	113	19	.	.	PUNCT
bptjm-66	114	1	however	however	ADV
bptjm-66	114	2	,	,	PUNCT
bptjm-66	114	3	with	with	ADP
bptjm-66	114	4	prolonged	prolonged	ADJ
bptjm-66	114	5	injury	injury	NOUN
bptjm-66	114	6	,	,	PUNCT
bptjm-66	114	7	this	this	DET
bptjm-66	114	8	response	response	NOUN
bptjm-66	114	9	diminishes	diminish	VERB
bptjm-66	114	10	,	,	PUNCT
bptjm-66	114	11	compromising	compromise	VERB
bptjm-66	114	12	the	the	DET
bptjm-66	114	13	descending	descend	VERB
bptjm-66	114	14	noradrenergic	noradrenergic	ADJ
bptjm-66	114	15	inhibitory	inhibitory	ADJ
bptjm-66	114	16	system	system	NOUN
bptjm-66	114	17	.	.	PUNCT
bptjm-66	115	1	antidepressants	antidepressant	NOUN
bptjm-66	115	2	intervene	intervene	ADJ
bptjm-66	115	3	by	by	ADP
bptjm-66	115	4	restoring	restore	VERB
bptjm-66	115	5	locus	locus	NOUN
bptjm-66	115	6	coeruleus	coeruleus	NOUN
bptjm-66	115	7	function	function	NOUN
bptjm-66	115	8	and	and	CCONJ
bptjm-66	115	9	increasing	increase	VERB
bptjm-66	115	10	noradrenaline	noradrenaline	ADJ
bptjm-66	115	11	levels21	levels21	NOUN
bptjm-66	115	12	.	.	PUNCT
bptjm-66	116	1	moreover	moreover	ADV
bptjm-66	116	2	,	,	PUNCT
bptjm-66	116	3	they	they	PRON
bptjm-66	116	4	elevate	elevate	VERB
bptjm-66	116	5	levels	level	NOUN
bptjm-66	116	6	of	of	ADP
bptjm-66	116	7	brain	brain	NOUN
bptjm-66	116	8	-	-	PUNCT
bptjm-66	116	9	derived	derive	VERB
bptjm-66	116	10	neurotrophic	neurotrophic	ADJ
bptjm-66	116	11	factor	factor	NOUN
bptjm-66	116	12	(	(	PUNCT
bptjm-66	116	13	bdnf	bdnf	PROPN
bptjm-66	116	14	)	)	PUNCT
bptjm-66	116	15	,	,	PUNCT
bptjm-66	116	16	crucial	crucial	ADJ
bptjm-66	116	17	for	for	ADP
bptjm-66	116	18	ampa	ampa	NOUN
bptjm-66	116	19	receptor	receptor	NOUN
bptjm-66	116	20	-	-	PUNCT
bptjm-66	116	21	mediated	mediate	VERB
bptjm-66	116	22	activation	activation	NOUN
bptjm-66	116	23	in	in	ADP
bptjm-66	116	24	the	the	DET
bptjm-66	116	25	locus	locus	NOUN
bptjm-66	116	26	coeruleus	coeruleus	NOUN
bptjm-66	116	27	,	,	PUNCT
bptjm-66	116	28	further	far	ADV
bptjm-66	116	29	promoting	promote	VERB
bptjm-66	116	30	analgesic	analgesic	ADJ
bptjm-66	116	31	effects	effect	NOUN
bptjm-66	116	32	.	.	PUNCT
bptjm-66	117	1	another	another	DET
bptjm-66	117	2	common	common	ADJ
bptjm-66	117	3	class	class	NOUN
bptjm-66	117	4	of	of	ADP
bptjm-66	117	5	adjuvant	adjuvant	ADJ
bptjm-66	117	6	analgesics	analgesic	NOUN
bptjm-66	117	7	,	,	PUNCT
bptjm-66	117	8	anticonvulsants	anticonvulsant	NOUN
bptjm-66	117	9	,	,	PUNCT
bptjm-66	117	10	exert	exert	VERB
bptjm-66	117	11	their	their	PRON
bptjm-66	117	12	analgesic	analgesic	ADJ
bptjm-66	117	13	effects	effect	NOUN
bptjm-66	117	14	by	by	ADP
bptjm-66	117	15	modulating	modulate	VERB
bptjm-66	117	16	neurotransmission	neurotransmission	NOUN
bptjm-66	117	17	to	to	PART
bptjm-66	117	18	prevent	prevent	VERB
bptjm-66	117	19	seizure	seizure	NOUN
bptjm-66	117	20	activity	activity	NOUN
bptjm-66	117	21	.	.	PUNCT
bptjm-66	118	1	the	the	DET
bptjm-66	118	2	drug	drug	NOUN
bptjm-66	118	3	acts	act	VERB
bptjm-66	118	4	on	on	ADP
bptjm-66	118	5	the	the	DET
bptjm-66	118	6	brain	brain	NOUN
bptjm-66	118	7	to	to	PART
bptjm-66	118	8	serve	serve	VERB
bptjm-66	118	9	its	its	PRON
bptjm-66	118	10	primary	primary	ADJ
bptjm-66	118	11	pharmaceutical	pharmaceutical	ADJ
bptjm-66	118	12	purpose	purpose	NOUN
bptjm-66	118	13	,	,	PUNCT
bptjm-66	118	14	which	which	PRON
bptjm-66	118	15	also	also	ADV
bptjm-66	118	16	inhibits	inhibit	VERB
bptjm-66	118	17	neurotransmission	neurotransmission	NOUN
bptjm-66	118	18	in	in	ADP
bptjm-66	118	19	pain	pain	NOUN
bptjm-66	118	20	reception	reception	NOUN
bptjm-66	118	21	.	.	PUNCT
bptjm-66	119	1	though	though	SCONJ
bptjm-66	119	2	the	the	DET
bptjm-66	119	3	listed	list	VERB
bptjm-66	119	4	adjuvant	adjuvant	ADJ
bptjm-66	119	5	analgesics	analgesic	NOUN
bptjm-66	119	6	manage	manage	VERB
bptjm-66	119	7	pain	pain	NOUN
bptjm-66	119	8	well	well	ADV
bptjm-66	119	9	,	,	PUNCT
bptjm-66	119	10	they	they	PRON
bptjm-66	119	11	do	do	AUX
bptjm-66	119	12	have	have	VERB
bptjm-66	119	13	side	side	NOUN
bptjm-66	119	14	effects	effect	NOUN
bptjm-66	119	15	;	;	PUNCT
bptjm-66	119	16	headaches	headache	NOUN
bptjm-66	119	17	,	,	PUNCT
bptjm-66	119	18	decreased	decrease	VERB
bptjm-66	119	19	alertness	alertness	NOUN
bptjm-66	119	20	,	,	PUNCT
bptjm-66	119	21	and	and	CCONJ
bptjm-66	119	22	bleeding	bleeding	NOUN
bptjm-66	119	23	are	be	AUX
bptjm-66	119	24	just	just	ADV
bptjm-66	119	25	some	some	PRON
bptjm-66	119	26	of	of	ADP
bptjm-66	119	27	the	the	DET
bptjm-66	119	28	problems	problem	NOUN
bptjm-66	119	29	that	that	PRON
bptjm-66	119	30	can	can	AUX
bptjm-66	119	31	arise	arise	VERB
bptjm-66	119	32	.	.	PUNCT
bptjm-66	120	1	2.2	2.2	NUM
bptjm-66	120	2	opioid	opioid	ADJ
bptjm-66	120	3	drugs	drug	VERB
bptjm-66	120	4	the	the	DET
bptjm-66	120	5	most	most	ADV
bptjm-66	120	6	hazardous	hazardous	ADJ
bptjm-66	120	7	class	class	NOUN
bptjm-66	120	8	of	of	ADP
bptjm-66	120	9	medications	medication	NOUN
bptjm-66	120	10	is	be	AUX
bptjm-66	120	11	opioids	opioid	NOUN
bptjm-66	120	12	.	.	PUNCT
bptjm-66	121	1	among	among	ADP
bptjm-66	121	2	the	the	DET
bptjm-66	121	3	commonly	commonly	ADV
bptjm-66	121	4	known	know	VERB
bptjm-66	121	5	opioids	opioid	NOUN
bptjm-66	121	6	are	be	AUX
bptjm-66	121	7	morphine	morphine	NOUN
bptjm-66	121	8	,	,	PUNCT
bptjm-66	121	9	oxycodone	oxycodone	NOUN
bptjm-66	121	10	,	,	PUNCT
bptjm-66	121	11	codeine	codeine	NOUN
bptjm-66	121	12	,	,	PUNCT
bptjm-66	121	13	dihydrocodeine	dihydrocodeine	NOUN
bptjm-66	121	14	,	,	PUNCT
bptjm-66	121	15	and	and	CCONJ
bptjm-66	121	16	loperamide	loperamide	NOUN
bptjm-66	121	17	,	,	PUNCT
bptjm-66	121	18	some	some	PRON
bptjm-66	121	19	of	of	ADP
bptjm-66	121	20	which	which	PRON
bptjm-66	121	21	are	be	AUX
bptjm-66	121	22	available	available	ADJ
bptjm-66	121	23	over	over	ADP
bptjm-66	121	24	the	the	DET
bptjm-66	121	25	counter	counter	NOUN
bptjm-66	121	26	without	without	ADP
bptjm-66	121	27	prescriptions	prescription	NOUN
bptjm-66	121	28	.	.	PUNCT
bptjm-66	122	1	despite	despite	SCONJ
bptjm-66	122	2	the	the	DET
bptjm-66	122	3	wide	wide	ADJ
bptjm-66	122	4	array	array	NOUN
bptjm-66	122	5	of	of	ADP
bptjm-66	122	6	opioid	opioid	NOUN
bptjm-66	122	7	-	-	PUNCT
bptjm-66	122	8	based	base	VERB
bptjm-66	122	9	drugs	drug	NOUN
bptjm-66	122	10	available	available	ADJ
bptjm-66	122	11	,	,	PUNCT
bptjm-66	122	12	they	they	PRON
bptjm-66	122	13	all	all	PRON
bptjm-66	122	14	share	share	VERB
bptjm-66	122	15	a	a	DET
bptjm-66	122	16	common	common	ADJ
bptjm-66	122	17	mechanism	mechanism	NOUN
bptjm-66	122	18	of	of	ADP
bptjm-66	122	19	action	action	NOUN
bptjm-66	122	20	,	,	PUNCT
bptjm-66	122	21	targeting	target	VERB
bptjm-66	122	22	the	the	DET
bptjm-66	122	23	mu	mu	PROPN
bptjm-66	122	24	,	,	PUNCT
bptjm-66	122	25	kappa	kappa	ADJ
bptjm-66	122	26	,	,	PUNCT
bptjm-66	122	27	and	and	CCONJ
bptjm-66	122	28	delta	delta	NOUN
bptjm-66	122	29	receptors	receptor	NOUN
bptjm-66	122	30	in	in	ADP
bptjm-66	122	31	the	the	DET
bptjm-66	122	32	nervous	nervous	ADJ
bptjm-66	122	33	system	system	NOUN
bptjm-66	122	34	.	.	PUNCT
bptjm-66	123	1	in	in	ADP
bptjm-66	123	2	the	the	DET
bptjm-66	123	3	context	context	NOUN
bptjm-66	123	4	of	of	ADP
bptjm-66	123	5	pain	pain	NOUN
bptjm-66	123	6	medicine	medicine	NOUN
bptjm-66	123	7	,	,	PUNCT
bptjm-66	123	8	the	the	DET
bptjm-66	123	9	mu	mu	PROPN
bptjm-66	123	10	berkeley	berkeley	PROPN
bptjm-66	123	11	pharma	pharma	PROPN
bptjm-66	123	12	tech	tech	NOUN
bptjm-66	123	13	journal	journal	NOUN
bptjm-66	123	14	of	of	ADP
bptjm-66	123	15	medicine	medicine	NOUN
bptjm-66	123	16	|	|	ADV
bptjm-66	123	17	8	8	NUM
bptjm-66	123	18	receptor	receptor	NOUN
bptjm-66	123	19	is	be	AUX
bptjm-66	123	20	of	of	ADP
bptjm-66	123	21	interest	interest	NOUN
bptjm-66	123	22	for	for	ADP
bptjm-66	123	23	its	its	PRON
bptjm-66	123	24	ability	ability	NOUN
bptjm-66	123	25	to	to	PART
bptjm-66	123	26	elicit	elicit	VERB
bptjm-66	123	27	analgesic	analgesic	ADJ
bptjm-66	123	28	effects	effect	NOUN
bptjm-66	123	29	.	.	PUNCT
bptjm-66	124	1	opioids	opioid	NOUN
bptjm-66	124	2	bind	bind	VERB
bptjm-66	124	3	to	to	ADP
bptjm-66	124	4	the	the	DET
bptjm-66	124	5	mu	mu	NOUN
bptjm-66	124	6	receptor	receptor	NOUN
bptjm-66	124	7	,	,	PUNCT
bptjm-66	124	8	decreasing	decrease	VERB
bptjm-66	124	9	the	the	DET
bptjm-66	124	10	excitability	excitability	NOUN
bptjm-66	124	11	of	of	ADP
bptjm-66	124	12	nociceptors	nociceptor	NOUN
bptjm-66	124	13	and	and	CCONJ
bptjm-66	124	14	the	the	DET
bptjm-66	124	15	release	release	NOUN
bptjm-66	124	16	of	of	ADP
bptjm-66	124	17	pro	pro	ADJ
bptjm-66	124	18	-	-	ADJ
bptjm-66	124	19	inflammatory	inflammatory	ADJ
bptjm-66	124	20	peptides22	peptides22	NOUN
bptjm-66	124	21	.	.	PUNCT
bptjm-66	125	1	however	however	ADV
bptjm-66	125	2	,	,	PUNCT
bptjm-66	125	3	this	this	PRON
bptjm-66	125	4	is	be	AUX
bptjm-66	125	5	not	not	PART
bptjm-66	125	6	all	all	DET
bptjm-66	125	7	the	the	DET
bptjm-66	125	8	drug	drug	NOUN
bptjm-66	125	9	does	do	VERB
bptjm-66	125	10	.	.	PUNCT
bptjm-66	126	1	the	the	DET
bptjm-66	126	2	kappa	kappa	ADJ
bptjm-66	126	3	receptor	receptor	NOUN
bptjm-66	126	4	induces	induce	VERB
bptjm-66	126	5	the	the	DET
bptjm-66	126	6	commonly	commonly	ADV
bptjm-66	126	7	known	know	VERB
bptjm-66	126	8	drug	drug	NOUN
bptjm-66	126	9	effects	effect	NOUN
bptjm-66	126	10	,	,	PUNCT
bptjm-66	126	11	like	like	ADP
bptjm-66	126	12	euphoria	euphoria	NOUN
bptjm-66	126	13	and	and	CCONJ
bptjm-66	126	14	depression	depression	NOUN
bptjm-66	126	15	of	of	ADP
bptjm-66	126	16	bodily	bodily	ADJ
bptjm-66	126	17	function	function	NOUN
bptjm-66	126	18	.	.	PUNCT
bptjm-66	127	1	the	the	DET
bptjm-66	127	2	addictiveness	addictiveness	NOUN
bptjm-66	127	3	of	of	ADP
bptjm-66	127	4	the	the	DET
bptjm-66	127	5	euphoria	euphoria	NOUN
bptjm-66	127	6	makes	make	VERB
bptjm-66	127	7	this	this	DET
bptjm-66	127	8	combination	combination	NOUN
bptjm-66	127	9	especially	especially	ADV
bptjm-66	127	10	dangerous	dangerous	ADJ
bptjm-66	127	11	.	.	PUNCT
bptjm-66	128	1	as	as	ADP
bptjm-66	128	2	depressants	depressant	NOUN
bptjm-66	128	3	,	,	PUNCT
bptjm-66	128	4	opioids	opioid	NOUN
bptjm-66	128	5	effectively	effectively	ADV
bptjm-66	128	6	slow	slow	VERB
bptjm-66	128	7	down	down	ADP
bptjm-66	128	8	bodily	bodily	ADJ
bptjm-66	128	9	functions	function	NOUN
bptjm-66	128	10	,	,	PUNCT
bptjm-66	128	11	including	include	VERB
bptjm-66	128	12	respiration	respiration	NOUN
bptjm-66	128	13	,	,	PUNCT
bptjm-66	128	14	which	which	PRON
bptjm-66	128	15	can	can	AUX
bptjm-66	128	16	lead	lead	VERB
bptjm-66	128	17	to	to	ADP
bptjm-66	128	18	respiratory	respiratory	ADJ
bptjm-66	128	19	depression	depression	NOUN
bptjm-66	128	20	and	and	CCONJ
bptjm-66	128	21	neuronal	neuronal	ADJ
bptjm-66	128	22	damage	damage	NOUN
bptjm-66	128	23	.	.	PUNCT
bptjm-66	129	1	the	the	DET
bptjm-66	129	2	unreliability	unreliability	NOUN
bptjm-66	129	3	of	of	ADP
bptjm-66	129	4	this	this	DET
bptjm-66	129	5	drug	drug	NOUN
bptjm-66	129	6	makes	make	VERB
bptjm-66	129	7	it	it	PRON
bptjm-66	129	8	undesirable	undesirable	ADJ
bptjm-66	129	9	as	as	ADP
bptjm-66	129	10	a	a	DET
bptjm-66	129	11	pain	pain	NOUN
bptjm-66	129	12	medicine	medicine	NOUN
bptjm-66	129	13	.	.	PUNCT
bptjm-66	130	1	nanoparticles	nanoparticle	NOUN
bptjm-66	130	2	,	,	PUNCT
bptjm-66	130	3	which	which	PRON
bptjm-66	130	4	will	will	AUX
bptjm-66	130	5	be	be	AUX
bptjm-66	130	6	discussed	discuss	VERB
bptjm-66	130	7	further	far	ADV
bptjm-66	130	8	on	on	ADV
bptjm-66	130	9	,	,	PUNCT
bptjm-66	130	10	hold	hold	VERB
bptjm-66	130	11	promise	promise	NOUN
bptjm-66	130	12	for	for	ADP
bptjm-66	130	13	providing	provide	VERB
bptjm-66	130	14	synergistic	synergistic	ADJ
bptjm-66	130	15	effects	effect	NOUN
bptjm-66	130	16	with	with	ADP
bptjm-66	130	17	opioids	opioid	NOUN
bptjm-66	130	18	,	,	PUNCT
bptjm-66	130	19	making	make	VERB
bptjm-66	130	20	them	they	PRON
bptjm-66	130	21	safer	safe	ADJ
bptjm-66	130	22	to	to	PART
bptjm-66	130	23	use	use	VERB
bptjm-66	130	24	.	.	PUNCT
bptjm-66	131	1	additionally	additionally	ADV
bptjm-66	131	2	,	,	PUNCT
bptjm-66	131	3	it	it	PRON
bptjm-66	131	4	is	be	AUX
bptjm-66	131	5	important	important	ADJ
bptjm-66	131	6	to	to	PART
bptjm-66	131	7	note	note	VERB
bptjm-66	131	8	that	that	SCONJ
bptjm-66	131	9	many	many	ADJ
bptjm-66	131	10	of	of	ADP
bptjm-66	131	11	the	the	DET
bptjm-66	131	12	commonly	commonly	ADV
bptjm-66	131	13	used	use	VERB
bptjm-66	131	14	opioids	opioid	NOUN
bptjm-66	131	15	do	do	AUX
bptjm-66	131	16	not	not	PART
bptjm-66	131	17	act	act	VERB
bptjm-66	131	18	on	on	ADP
bptjm-66	131	19	all	all	PRON
bptjm-66	131	20	of	of	ADP
bptjm-66	131	21	the	the	DET
bptjm-66	131	22	opioid	opioid	ADJ
bptjm-66	131	23	receptors	receptor	NOUN
bptjm-66	131	24	.	.	PUNCT
bptjm-66	132	1	although	although	SCONJ
bptjm-66	132	2	the	the	DET
bptjm-66	132	3	majority	majority	NOUN
bptjm-66	132	4	of	of	ADP
bptjm-66	132	5	them	they	PRON
bptjm-66	132	6	act	act	VERB
bptjm-66	132	7	mainly	mainly	ADV
bptjm-66	132	8	on	on	ADP
bptjm-66	132	9	the	the	DET
bptjm-66	132	10	mu	mu	NOUN
bptjm-66	132	11	receptor	receptor	NOUN
bptjm-66	132	12	,	,	PUNCT
bptjm-66	132	13	they	they	PRON
bptjm-66	132	14	do	do	AUX
bptjm-66	132	15	not	not	PART
bptjm-66	132	16	act	act	VERB
bptjm-66	132	17	on	on	ADP
bptjm-66	132	18	the	the	DET
bptjm-66	132	19	other	other	ADJ
bptjm-66	132	20	two	two	NUM
bptjm-66	132	21	receptors	receptor	NOUN
bptjm-66	132	22	.	.	PUNCT
bptjm-66	133	1	for	for	ADP
bptjm-66	133	2	example	example	NOUN
bptjm-66	133	3	,	,	PUNCT
bptjm-66	133	4	oxycodone	oxycodone	NOUN
bptjm-66	133	5	,	,	PUNCT
bptjm-66	133	6	codeine	codeine	NOUN
bptjm-66	133	7	,	,	PUNCT
bptjm-66	133	8	and	and	CCONJ
bptjm-66	133	9	loperamide	loperamide	NOUN
bptjm-66	133	10	are	be	AUX
bptjm-66	133	11	all	all	PRON
bptjm-66	133	12	opioids	opioid	NOUN
bptjm-66	133	13	that	that	PRON
bptjm-66	133	14	are	be	AUX
bptjm-66	133	15	agonists	agonist	NOUN
bptjm-66	133	16	on	on	ADP
bptjm-66	133	17	the	the	DET
bptjm-66	133	18	mu	mu	NOUN
bptjm-66	133	19	receptor	receptor	NOUN
bptjm-66	133	20	.	.	PUNCT
bptjm-66	134	1	morphine	morphine	PROPN
bptjm-66	134	2	affects	affect	VERB
bptjm-66	134	3	each	each	PRON
bptjm-66	134	4	of	of	ADP
bptjm-66	134	5	the	the	DET
bptjm-66	134	6	receptors	receptor	NOUN
bptjm-66	134	7	but	but	CCONJ
bptjm-66	134	8	binds	bind	VERB
bptjm-66	134	9	mainly	mainly	ADV
bptjm-66	134	10	to	to	ADP
bptjm-66	134	11	the	the	DET
bptjm-66	134	12	mu	mu	NOUN
bptjm-66	134	13	receptor	receptor	NOUN
bptjm-66	134	14	.	.	PUNCT
bptjm-66	135	1	when	when	SCONJ
bptjm-66	135	2	morphine	morphine	NOUN
bptjm-66	135	3	binds	bind	VERB
bptjm-66	135	4	with	with	ADP
bptjm-66	135	5	these	these	DET
bptjm-66	135	6	receptors	receptor	NOUN
bptjm-66	135	7	it	it	PRON
bptjm-66	135	8	leads	lead	VERB
bptjm-66	135	9	to	to	ADP
bptjm-66	135	10	an	an	DET
bptjm-66	135	11	activation	activation	NOUN
bptjm-66	135	12	of	of	ADP
bptjm-66	135	13	the	the	DET
bptjm-66	135	14	descending	descend	VERB
bptjm-66	135	15	inhibitory	inhibitory	ADJ
bptjm-66	135	16	pathways	pathway	NOUN
bptjm-66	135	17	of	of	ADP
bptjm-66	135	18	the	the	DET
bptjm-66	135	19	central	central	ADJ
bptjm-66	135	20	nervous	nervous	ADJ
bptjm-66	135	21	system	system	NOUN
bptjm-66	135	22	resulting	result	VERB
bptjm-66	135	23	in	in	ADP
bptjm-66	135	24	reduced	reduced	ADJ
bptjm-66	135	25	nociceptive	nociceptive	ADJ
bptjm-66	135	26	signal	signal	NOUN
bptjm-66	135	27	transmission23	transmission23	NOUN
bptjm-66	135	28	.	.	PUNCT
bptjm-66	136	1	although	although	SCONJ
bptjm-66	136	2	morphine	morphine	NOUN
bptjm-66	136	3	has	have	AUX
bptjm-66	136	4	been	be	AUX
bptjm-66	136	5	shown	show	VERB
bptjm-66	136	6	to	to	PART
bptjm-66	136	7	decrease	decrease	VERB
bptjm-66	136	8	blood	blood	NOUN
bptjm-66	136	9	pressure	pressure	NOUN
bptjm-66	136	10	and	and	CCONJ
bptjm-66	136	11	heart	heart	NOUN
bptjm-66	136	12	rate	rate	NOUN
bptjm-66	136	13	,	,	PUNCT
bptjm-66	136	14	it	it	PRON
bptjm-66	136	15	has	have	VERB
bptjm-66	136	16	some	some	DET
bptjm-66	136	17	unfavorable	unfavorable	ADJ
bptjm-66	136	18	effects	effect	NOUN
bptjm-66	136	19	such	such	ADJ
bptjm-66	136	20	as	as	ADP
bptjm-66	136	21	constipation	constipation	NOUN
bptjm-66	136	22	,	,	PUNCT
bptjm-66	136	23	nausea	nausea	NOUN
bptjm-66	136	24	,	,	PUNCT
bptjm-66	136	25	depression	depression	NOUN
bptjm-66	136	26	,	,	PUNCT
bptjm-66	136	27	and	and	CCONJ
bptjm-66	136	28	vomiting	vomiting	NOUN
bptjm-66	136	29	.	.	PUNCT
bptjm-66	137	1	pentazocine	pentazocine	NOUN
bptjm-66	137	2	is	be	AUX
bptjm-66	137	3	not	not	PART
bptjm-66	137	4	as	as	ADV
bptjm-66	137	5	commonly	commonly	ADV
bptjm-66	137	6	used	use	VERB
bptjm-66	137	7	at	at	ADP
bptjm-66	137	8	present	present	ADJ
bptjm-66	137	9	but	but	CCONJ
bptjm-66	137	10	is	be	AUX
bptjm-66	137	11	a	a	DET
bptjm-66	137	12	synthetic	synthetic	ADJ
bptjm-66	137	13	opioid	opioid	NOUN
bptjm-66	137	14	used	use	VERB
bptjm-66	137	15	as	as	ADP
bptjm-66	137	16	an	an	DET
bptjm-66	137	17	agonist	agonist	NOUN
bptjm-66	137	18	on	on	ADP
bptjm-66	137	19	the	the	DET
bptjm-66	137	20	kappa	kappa	PROPN
bptjm-66	137	21	(	(	PUNCT
bptjm-66	137	22	κ	κ	NOUN
bptjm-66	137	23	)	)	PUNCT
bptjm-66	137	24	receptor24	receptor24	NOUN
bptjm-66	137	25	.	.	PUNCT
bptjm-66	138	1	pentazocine	pentazocine	NOUN
bptjm-66	138	2	does	do	AUX
bptjm-66	138	3	have	have	VERB
bptjm-66	138	4	the	the	DET
bptjm-66	138	5	chance	chance	NOUN
bptjm-66	138	6	of	of	ADP
bptjm-66	138	7	common	common	ADJ
bptjm-66	138	8	adverse	adverse	ADJ
bptjm-66	138	9	effects	effect	NOUN
bptjm-66	138	10	of	of	ADP
bptjm-66	138	11	opioids	opioid	NOUN
bptjm-66	138	12	such	such	ADJ
bptjm-66	138	13	as	as	ADP
bptjm-66	138	14	nausea	nausea	NOUN
bptjm-66	138	15	,	,	PUNCT
bptjm-66	138	16	respiratory	respiratory	ADJ
bptjm-66	138	17	depression	depression	NOUN
bptjm-66	138	18	,	,	PUNCT
bptjm-66	138	19	vomiting	vomiting	NOUN
bptjm-66	138	20	,	,	PUNCT
bptjm-66	138	21	and	and	CCONJ
bptjm-66	138	22	constipation	constipation	NOUN
bptjm-66	138	23	.	.	PUNCT
bptjm-66	139	1	the	the	DET
bptjm-66	139	2	final	final	ADJ
bptjm-66	139	3	opioid	opioid	ADJ
bptjm-66	139	4	receptor	receptor	NOUN
bptjm-66	139	5	,	,	PUNCT
bptjm-66	139	6	the	the	DET
bptjm-66	139	7	delta	delta	NOUN
bptjm-66	139	8	receptor	receptor	NOUN
bptjm-66	139	9	,	,	PUNCT
bptjm-66	139	10	is	be	AUX
bptjm-66	139	11	known	know	VERB
bptjm-66	139	12	to	to	PART
bptjm-66	139	13	associate	associate	VERB
bptjm-66	139	14	with	with	ADP
bptjm-66	139	15	the	the	DET
bptjm-66	139	16	drug	drug	NOUN
bptjm-66	139	17	named	name	VERB
bptjm-66	139	18	buprenorphine	buprenorphine	NOUN
bptjm-66	139	19	.	.	PUNCT
bptjm-66	140	1	buprenorphine	buprenorphine	NOUN
bptjm-66	140	2	is	be	AUX
bptjm-66	140	3	also	also	ADV
bptjm-66	140	4	known	know	VERB
bptjm-66	140	5	to	to	PART
bptjm-66	140	6	be	be	AUX
bptjm-66	140	7	a	a	DET
bptjm-66	140	8	partial	partial	ADJ
bptjm-66	140	9	agonist	agonist	NOUN
bptjm-66	140	10	to	to	ADP
bptjm-66	140	11	mu	mu	NOUN
bptjm-66	140	12	receptors	receptor	NOUN
bptjm-66	140	13	and	and	CCONJ
bptjm-66	140	14	a	a	DET
bptjm-66	140	15	weak	weak	ADJ
bptjm-66	140	16	antagonist	antagonist	NOUN
bptjm-66	140	17	at	at	ADP
bptjm-66	140	18	kappa	kappa	ADJ
bptjm-66	140	19	receptors	receptor	NOUN
bptjm-66	140	20	,	,	PUNCT
bptjm-66	140	21	but	but	CCONJ
bptjm-66	140	22	its	its	PRON
bptjm-66	140	23	effects	effect	NOUN
bptjm-66	140	24	on	on	ADP
bptjm-66	140	25	delta	delta	NOUN
bptjm-66	140	26	receptors	receptor	NOUN
bptjm-66	140	27	are	be	AUX
bptjm-66	140	28	also	also	ADV
bptjm-66	140	29	weak	weak	ADJ
bptjm-66	140	30	.	.	PUNCT
bptjm-66	141	1	it	it	PRON
bptjm-66	141	2	is	be	AUX
bptjm-66	141	3	a	a	DET
bptjm-66	141	4	synthetic	synthetic	ADJ
bptjm-66	141	5	opioid	opioid	NOUN
bptjm-66	141	6	that	that	PRON
bptjm-66	141	7	is	be	AUX
bptjm-66	141	8	used	use	VERB
bptjm-66	141	9	for	for	ADP
bptjm-66	141	10	pain	pain	NOUN
bptjm-66	141	11	treatment	treatment	NOUN
bptjm-66	141	12	and	and	CCONJ
bptjm-66	141	13	opioid	opioid	ADJ
bptjm-66	141	14	use	use	NOUN
bptjm-66	141	15	disorders	disorder	NOUN
bptjm-66	141	16	(	(	PUNCT
bptjm-66	141	17	oud	oud	NOUN
bptjm-66	141	18	)	)	PUNCT
bptjm-66	141	19	.	.	PUNCT
bptjm-66	142	1	it	it	PRON
bptjm-66	142	2	acts	act	VERB
bptjm-66	142	3	differently	differently	ADV
bptjm-66	142	4	from	from	ADP
bptjm-66	142	5	normal	normal	ADJ
bptjm-66	142	6	opioids	opioid	NOUN
bptjm-66	142	7	by	by	ADP
bptjm-66	142	8	exhibiting	exhibit	VERB
bptjm-66	142	9	slow	slow	ADJ
bptjm-66	142	10	dissociation	dissociation	NOUN
bptjm-66	142	11	kinetics	kinetic	NOUN
bptjm-66	142	12	,	,	PUNCT
bptjm-66	142	13	allowing	allow	VERB
bptjm-66	142	14	for	for	ADP
bptjm-66	142	15	fewer	few	ADJ
bptjm-66	142	16	adverse	adverse	ADJ
bptjm-66	142	17	effects	effect	NOUN
bptjm-66	142	18	.	.	PUNCT
bptjm-66	143	1	berkeley	berkeley	PROPN
bptjm-66	143	2	pharma	pharma	PROPN
bptjm-66	143	3	tech	tech	PROPN
bptjm-66	143	4	journal	journal	NOUN
bptjm-66	143	5	of	of	ADP
bptjm-66	143	6	medicine	medicine	NOUN
bptjm-66	143	7	|	|	ADV
bptjm-66	143	8	9	9	NUM
bptjm-66	143	9	though	though	SCONJ
bptjm-66	143	10	current	current	ADJ
bptjm-66	143	11	drugs	drug	NOUN
bptjm-66	143	12	on	on	ADP
bptjm-66	143	13	the	the	DET
bptjm-66	143	14	market	market	NOUN
bptjm-66	143	15	have	have	AUX
bptjm-66	143	16	proven	prove	VERB
bptjm-66	143	17	their	their	PRON
bptjm-66	143	18	use	use	NOUN
bptjm-66	143	19	over	over	ADP
bptjm-66	143	20	the	the	DET
bptjm-66	143	21	years	year	NOUN
bptjm-66	143	22	,	,	PUNCT
bptjm-66	143	23	there	there	PRON
bptjm-66	143	24	are	be	VERB
bptjm-66	143	25	many	many	ADJ
bptjm-66	143	26	avenues	avenue	NOUN
bptjm-66	143	27	of	of	ADP
bptjm-66	143	28	innovation	innovation	NOUN
bptjm-66	143	29	in	in	ADP
bptjm-66	143	30	the	the	DET
bptjm-66	143	31	field	field	NOUN
bptjm-66	143	32	of	of	ADP
bptjm-66	143	33	medicine	medicine	NOUN
bptjm-66	143	34	that	that	PRON
bptjm-66	143	35	can	can	AUX
bptjm-66	143	36	elevate	elevate	VERB
bptjm-66	143	37	the	the	DET
bptjm-66	143	38	current	current	ADJ
bptjm-66	143	39	drugs	drug	NOUN
bptjm-66	143	40	on	on	ADP
bptjm-66	143	41	the	the	DET
bptjm-66	143	42	market	market	NOUN
bptjm-66	143	43	as	as	ADV
bptjm-66	143	44	well	well	ADV
bptjm-66	143	45	as	as	ADP
bptjm-66	143	46	provide	provide	VERB
bptjm-66	143	47	alternate	alternate	ADJ
bptjm-66	143	48	approaches	approach	NOUN
bptjm-66	143	49	to	to	ADP
bptjm-66	143	50	pain	pain	NOUN
bptjm-66	143	51	remedies	remedy	NOUN
bptjm-66	143	52	.	.	PUNCT
bptjm-66	144	1	3	3	X
bptjm-66	144	2	.	.	X
bptjm-66	144	3	pharmaceutical	pharmaceutical	NOUN
bptjm-66	144	4	remedies	remedy	NOUN
bptjm-66	144	5	advancements	advancement	NOUN
bptjm-66	144	6	3.1	3.1	NUM
bptjm-66	144	7	nanoparticles	nanoparticle	NOUN
bptjm-66	144	8	in	in	ADP
bptjm-66	144	9	contrast	contrast	NOUN
bptjm-66	144	10	to	to	ADP
bptjm-66	144	11	the	the	DET
bptjm-66	144	12	pharmaceutical	pharmaceutical	ADJ
bptjm-66	144	13	remedies	remedy	NOUN
bptjm-66	144	14	mentioned	mention	VERB
bptjm-66	144	15	earlier	early	ADV
bptjm-66	144	16	,	,	PUNCT
bptjm-66	144	17	nanoparticles	nanoparticle	NOUN
bptjm-66	144	18	demonstrate	demonstrate	VERB
bptjm-66	144	19	therapeutic	therapeutic	ADJ
bptjm-66	144	20	effects	effect	NOUN
bptjm-66	144	21	stemming	stem	VERB
bptjm-66	144	22	from	from	ADP
bptjm-66	144	23	the	the	DET
bptjm-66	144	24	emerging	emerge	VERB
bptjm-66	144	25	field	field	NOUN
bptjm-66	144	26	of	of	ADP
bptjm-66	144	27	nanotechnology	nanotechnology	NOUN
bptjm-66	144	28	.	.	PUNCT
bptjm-66	145	1	the	the	DET
bptjm-66	145	2	wide	wide	ADJ
bptjm-66	145	3	attributes	attribute	NOUN
bptjm-66	145	4	and	and	CCONJ
bptjm-66	145	5	modifications	modification	NOUN
bptjm-66	145	6	for	for	ADP
bptjm-66	145	7	nanoparticles	nanoparticle	NOUN
bptjm-66	145	8	enable	enable	VERB
bptjm-66	145	9	treatment	treatment	NOUN
bptjm-66	145	10	for	for	ADP
bptjm-66	145	11	a	a	DET
bptjm-66	145	12	diverse	diverse	ADJ
bptjm-66	145	13	spectrum	spectrum	NOUN
bptjm-66	145	14	of	of	ADP
bptjm-66	145	15	diseases	disease	NOUN
bptjm-66	145	16	,	,	PUNCT
bptjm-66	145	17	as	as	ADV
bptjm-66	145	18	well	well	ADV
bptjm-66	145	19	as	as	ADP
bptjm-66	145	20	an	an	DET
bptjm-66	145	21	avenue	avenue	NOUN
bptjm-66	145	22	to	to	ADP
bptjm-66	145	23	the	the	DET
bptjm-66	145	24	next	next	ADJ
bptjm-66	145	25	age	age	NOUN
bptjm-66	145	26	of	of	ADP
bptjm-66	145	27	precision	precision	NOUN
bptjm-66	145	28	medicine	medicine	NOUN
bptjm-66	145	29	.	.	PUNCT
bptjm-66	146	1	this	this	DET
bptjm-66	146	2	review	review	NOUN
bptjm-66	146	3	article	article	NOUN
bptjm-66	146	4	will	will	AUX
bptjm-66	146	5	explore	explore	VERB
bptjm-66	146	6	the	the	DET
bptjm-66	146	7	various	various	ADJ
bptjm-66	146	8	avenues	avenue	NOUN
bptjm-66	146	9	and	and	CCONJ
bptjm-66	146	10	types	type	NOUN
bptjm-66	146	11	of	of	ADP
bptjm-66	146	12	nanoparticles	nanoparticle	NOUN
bptjm-66	146	13	that	that	PRON
bptjm-66	146	14	are	be	AUX
bptjm-66	146	15	relevant	relevant	ADJ
bptjm-66	146	16	in	in	ADP
bptjm-66	146	17	a	a	DET
bptjm-66	146	18	pharmaceutical	pharmaceutical	ADJ
bptjm-66	146	19	context	context	NOUN
bptjm-66	146	20	.	.	PUNCT
bptjm-66	147	1	3.2	3.2	NUM
bptjm-66	147	2	zno	zno	PROPN
bptjm-66	147	3	&	&	CCONJ
bptjm-66	147	4	mgo	mgo	PROPN
bptjm-66	147	5	np	np	INTJ
bptjm-66	147	6	starting	start	VERB
bptjm-66	147	7	with	with	ADP
bptjm-66	147	8	zinc	zinc	NOUN
bptjm-66	147	9	oxide	oxide	NOUN
bptjm-66	147	10	,	,	PUNCT
bptjm-66	147	11	its	its	PRON
bptjm-66	147	12	wide	wide	ADJ
bptjm-66	147	13	range	range	NOUN
bptjm-66	147	14	of	of	ADP
bptjm-66	147	15	capabilities	capability	NOUN
bptjm-66	147	16	places	place	VERB
bptjm-66	147	17	it	it	PRON
bptjm-66	147	18	at	at	ADP
bptjm-66	147	19	the	the	DET
bptjm-66	147	20	forefront	forefront	NOUN
bptjm-66	147	21	of	of	ADP
bptjm-66	147	22	scientific	scientific	ADJ
bptjm-66	147	23	research	research	NOUN
bptjm-66	147	24	.	.	PUNCT
bptjm-66	148	1	zinc	zinc	NOUN
bptjm-66	148	2	,	,	PUNCT
bptjm-66	148	3	recognized	recognize	VERB
bptjm-66	148	4	as	as	ADP
bptjm-66	148	5	an	an	DET
bptjm-66	148	6	essential	essential	ADJ
bptjm-66	148	7	trace	trace	NOUN
bptjm-66	148	8	element	element	NOUN
bptjm-66	148	9	,	,	PUNCT
bptjm-66	148	10	plays	play	VERB
bptjm-66	148	11	a	a	DET
bptjm-66	148	12	crucial	crucial	ADJ
bptjm-66	148	13	role	role	NOUN
bptjm-66	148	14	in	in	ADP
bptjm-66	148	15	pain	pain	NOUN
bptjm-66	148	16	perception	perception	NOUN
bptjm-66	148	17	modulation	modulation	NOUN
bptjm-66	148	18	,	,	PUNCT
bptjm-66	148	19	proving	prove	VERB
bptjm-66	148	20	its	its	PRON
bptjm-66	148	21	ability	ability	NOUN
bptjm-66	148	22	to	to	PART
bptjm-66	148	23	analgesia	analgesia	VERB
bptjm-66	148	24	through	through	ADP
bptjm-66	148	25	various	various	ADJ
bptjm-66	148	26	pathways25	pathways25	NOUN
bptjm-66	148	27	.	.	PUNCT
bptjm-66	149	1	zinc	zinc	NOUN
bptjm-66	149	2	ions	ion	NOUN
bptjm-66	149	3	have	have	AUX
bptjm-66	149	4	been	be	AUX
bptjm-66	149	5	shown	show	VERB
bptjm-66	149	6	to	to	PART
bptjm-66	149	7	inhibit	inhibit	VERB
bptjm-66	149	8	the	the	DET
bptjm-66	149	9	release	release	NOUN
bptjm-66	149	10	of	of	ADP
bptjm-66	149	11	glutamate	glutamate	NOUN
bptjm-66	149	12	,	,	PUNCT
bptjm-66	149	13	a	a	DET
bptjm-66	149	14	previously	previously	ADV
bptjm-66	149	15	mentioned	mention	VERB
bptjm-66	149	16	neurotransmitter	neurotransmitter	NOUN
bptjm-66	149	17	by	by	ADP
bptjm-66	149	18	producing	produce	VERB
bptjm-66	149	19	more	more	ADJ
bptjm-66	149	20	gaba	gaba	NOUN
bptjm-66	149	21	,	,	PUNCT
bptjm-66	149	22	an	an	DET
bptjm-66	149	23	inhibitory	inhibitory	ADJ
bptjm-66	149	24	neurotransmitter	neurotransmitter	NOUN
bptjm-66	149	25	.	.	PUNCT
bptjm-66	150	1	furthermore	furthermore	ADV
bptjm-66	150	2	,	,	PUNCT
bptjm-66	150	3	zinc	zinc	NOUN
bptjm-66	150	4	ions	ion	NOUN
bptjm-66	150	5	noncompetitively	noncompetitively	ADV
bptjm-66	150	6	inhibit	inhibit	VERB
bptjm-66	150	7	the	the	DET
bptjm-66	150	8	nmda	nmda	ADJ
bptjm-66	150	9	receptor	receptor	NOUN
bptjm-66	150	10	,	,	PUNCT
bptjm-66	150	11	which	which	PRON
bptjm-66	150	12	diminishes	diminish	VERB
bptjm-66	150	13	the	the	DET
bptjm-66	150	14	activation	activation	NOUN
bptjm-66	150	15	of	of	ADP
bptjm-66	150	16	the	the	DET
bptjm-66	150	17	central	central	ADJ
bptjm-66	150	18	nervous	nervous	ADJ
bptjm-66	150	19	system	system	NOUN
bptjm-66	150	20	,	,	PUNCT
bptjm-66	150	21	the	the	DET
bptjm-66	150	22	perception	perception	NOUN
bptjm-66	150	23	pathway	pathway	NOUN
bptjm-66	150	24	for	for	ADP
bptjm-66	150	25	pain	pain	NOUN
bptjm-66	150	26	.	.	PUNCT
bptjm-66	151	1	what	what	PRON
bptjm-66	151	2	differentiates	differentiate	VERB
bptjm-66	151	3	the	the	DET
bptjm-66	151	4	nanoparticle	nanoparticle	NOUN
bptjm-66	151	5	from	from	ADP
bptjm-66	151	6	the	the	DET
bptjm-66	151	7	microparticle	microparticle	NOUN
bptjm-66	151	8	form	form	NOUN
bptjm-66	151	9	is	be	AUX
bptjm-66	151	10	the	the	DET
bptjm-66	151	11	penetration	penetration	NOUN
bptjm-66	151	12	efficiency	efficiency	NOUN
bptjm-66	151	13	;	;	PUNCT
bptjm-66	151	14	nanoparticles	nanoparticle	NOUN
bptjm-66	151	15	are	be	AUX
bptjm-66	151	16	three	three	NUM
bptjm-66	151	17	orders	order	NOUN
bptjm-66	151	18	of	of	ADP
bptjm-66	151	19	magnitude	magnitude	NOUN
bptjm-66	151	20	smaller	small	ADJ
bptjm-66	151	21	,	,	PUNCT
bptjm-66	151	22	contributing	contribute	VERB
bptjm-66	151	23	to	to	ADP
bptjm-66	151	24	their	their	PRON
bptjm-66	151	25	greater	great	ADJ
bptjm-66	151	26	motility	motility	NOUN
bptjm-66	151	27	through	through	ADP
bptjm-66	151	28	various	various	ADJ
bptjm-66	151	29	tissues26	tissues26	NOUN
bptjm-66	151	30	.	.	PUNCT
bptjm-66	152	1	as	as	ADP
bptjm-66	152	2	a	a	DET
bptjm-66	152	3	result	result	NOUN
bptjm-66	152	4	,	,	PUNCT
bptjm-66	152	5	smaller	small	ADJ
bptjm-66	152	6	doses	dose	NOUN
bptjm-66	152	7	of	of	ADP
bptjm-66	152	8	zinc	zinc	NOUN
bptjm-66	152	9	oxide	oxide	NOUN
bptjm-66	152	10	are	be	AUX
bptjm-66	152	11	required	require	VERB
bptjm-66	152	12	to	to	PART
bptjm-66	152	13	induce	induce	VERB
bptjm-66	152	14	saturation	saturation	NOUN
bptjm-66	152	15	.	.	PUNCT
bptjm-66	153	1	furthermore	furthermore	ADV
bptjm-66	153	2	,	,	PUNCT
bptjm-66	153	3	zinc	zinc	NOUN
bptjm-66	153	4	oxide	oxide	NOUN
bptjm-66	153	5	demonstrates	demonstrate	VERB
bptjm-66	153	6	photocatalytic	photocatalytic	ADJ
bptjm-66	153	7	capabilities	capability	NOUN
bptjm-66	153	8	,	,	PUNCT
bptjm-66	153	9	due	due	ADP
bptjm-66	153	10	to	to	ADP
bptjm-66	153	11	the	the	DET
bptjm-66	153	12	high	high	ADJ
bptjm-66	153	13	reactivity	reactivity	NOUN
bptjm-66	153	14	of	of	ADP
bptjm-66	153	15	surface	surface	NOUN
bptjm-66	153	16	oxygen	oxygen	NOUN
bptjm-66	153	17	atoms	atom	NOUN
bptjm-66	153	18	.	.	PUNCT
bptjm-66	154	1	it	it	PRON
bptjm-66	154	2	has	have	AUX
bptjm-66	154	3	proven	prove	VERB
bptjm-66	154	4	to	to	PART
bptjm-66	154	5	oxidize	oxidize	VERB
bptjm-66	154	6	stimulants	stimulant	NOUN
bptjm-66	154	7	on	on	ADP
bptjm-66	154	8	peripheral	peripheral	ADJ
bptjm-66	154	9	receptors	receptor	NOUN
bptjm-66	154	10	,	,	PUNCT
bptjm-66	154	11	and	and	CCONJ
bptjm-66	154	12	various	various	ADJ
bptjm-66	154	13	tumors	tumor	NOUN
bptjm-66	154	14	in	in	ADP
bptjm-66	154	15	cancer	cancer	NOUN
bptjm-66	154	16	therapy	therapy	NOUN
bptjm-66	154	17	.	.	PUNCT
bptjm-66	155	1	magnesium	magnesium	NOUN
bptjm-66	155	2	oxide	oxide	NOUN
bptjm-66	155	3	serves	serve	VERB
bptjm-66	155	4	a	a	DET
bptjm-66	155	5	similar	similar	ADJ
bptjm-66	155	6	role	role	NOUN
bptjm-66	155	7	,	,	PUNCT
bptjm-66	155	8	as	as	SCONJ
bptjm-66	155	9	it	it	PRON
bptjm-66	155	10	is	be	AUX
bptjm-66	155	11	another	another	DET
bptjm-66	155	12	vital	vital	ADJ
bptjm-66	155	13	cation	cation	NOUN
bptjm-66	155	14	in	in	ADP
bptjm-66	155	15	the	the	DET
bptjm-66	155	16	human	human	ADJ
bptjm-66	155	17	body	body	NOUN
bptjm-66	155	18	that	that	PRON
bptjm-66	155	19	offers	offer	VERB
bptjm-66	155	20	promising	promise	VERB
bptjm-66	155	21	avenues	avenue	NOUN
bptjm-66	155	22	for	for	ADP
bptjm-66	155	23	pain	pain	NOUN
bptjm-66	155	24	relief	relief	NOUN
bptjm-66	155	25	.	.	PUNCT
bptjm-66	156	1	by	by	ADP
bptjm-66	156	2	preventing	prevent	VERB
bptjm-66	156	3	the	the	DET
bptjm-66	156	4	calcium	calcium	NOUN
bptjm-66	156	5	ions	ion	NOUN
bptjm-66	156	6	from	from	ADP
bptjm-66	156	7	entering	enter	VERB
bptjm-66	156	8	cells	cell	NOUN
bptjm-66	156	9	through	through	ADP
bptjm-66	156	10	blocking	block	VERB
bptjm-66	156	11	nmda	nmda	ADJ
bptjm-66	156	12	receptors	receptor	NOUN
bptjm-66	156	13	,	,	PUNCT
bptjm-66	156	14	it	it	PRON
bptjm-66	156	15	serves	serve	VERB
bptjm-66	156	16	as	as	ADP
bptjm-66	156	17	another	another	DET
bptjm-66	156	18	berkeley	berkeley	PROPN
bptjm-66	156	19	pharma	pharma	PROPN
bptjm-66	156	20	tech	tech	NOUN
bptjm-66	156	21	journal	journal	NOUN
bptjm-66	156	22	of	of	ADP
bptjm-66	156	23	medicine	medicine	NOUN
bptjm-66	156	24	|	|	ADV
bptjm-66	156	25	10	10	NUM
bptjm-66	156	26	analgesic	analgesic	ADJ
bptjm-66	156	27	agent	agent	NOUN
bptjm-66	156	28	.	.	PUNCT
bptjm-66	157	1	one	one	NUM
bptjm-66	157	2	study27	study27	NOUN
bptjm-66	157	3	was	be	AUX
bptjm-66	157	4	conducted	conduct	VERB
bptjm-66	157	5	to	to	PART
bptjm-66	157	6	test	test	VERB
bptjm-66	157	7	this	this	DET
bptjm-66	157	8	reaction	reaction	NOUN
bptjm-66	157	9	on	on	ADP
bptjm-66	157	10	mice	mouse	NOUN
bptjm-66	157	11	.	.	PUNCT
bptjm-66	158	1	varying	vary	VERB
bptjm-66	158	2	doses	dose	NOUN
bptjm-66	158	3	of	of	ADP
bptjm-66	158	4	zinc	zinc	NOUN
bptjm-66	158	5	oxide	oxide	NOUN
bptjm-66	158	6	nanoparticles	nanoparticle	NOUN
bptjm-66	158	7	were	be	AUX
bptjm-66	158	8	injected	inject	VERB
bptjm-66	158	9	into	into	ADP
bptjm-66	158	10	rats	rat	NOUN
bptjm-66	158	11	(	(	PUNCT
bptjm-66	158	12	0	0	NUM
bptjm-66	158	13	,	,	PUNCT
bptjm-66	158	14	1	1	NUM
bptjm-66	158	15	,	,	PUNCT
bptjm-66	158	16	5	5	NUM
bptjm-66	158	17	,	,	PUNCT
bptjm-66	158	18	10	10	NUM
bptjm-66	158	19	,	,	PUNCT
bptjm-66	158	20	20	20	NUM
bptjm-66	158	21	mg	mg	NUM
bptjm-66	158	22	/	/	SYM
bptjm-66	158	23	kg	kg	NOUN
bptjm-66	158	24	)	)	PUNCT
bptjm-66	158	25	and	and	CCONJ
bptjm-66	158	26	the	the	DET
bptjm-66	158	27	latency	latency	NOUN
bptjm-66	158	28	in	in	ADP
bptjm-66	158	29	pain	pain	NOUN
bptjm-66	158	30	was	be	AUX
bptjm-66	158	31	measured	measure	VERB
bptjm-66	158	32	.	.	PUNCT
bptjm-66	159	1	as	as	SCONJ
bptjm-66	159	2	shown	show	VERB
bptjm-66	159	3	in	in	ADP
bptjm-66	159	4	figure	figure	NOUN
bptjm-66	159	5	1	1	NUM
bptjm-66	159	6	,	,	PUNCT
bptjm-66	159	7	the	the	DET
bptjm-66	159	8	latency	latency	NOUN
bptjm-66	159	9	period	period	NOUN
bptjm-66	159	10	was	be	AUX
bptjm-66	159	11	longest	long	ADJ
bptjm-66	159	12	at	at	ADP
bptjm-66	159	13	about	about	ADV
bptjm-66	159	14	10	10	NUM
bptjm-66	159	15	mg	mg	NUM
bptjm-66	159	16	/	/	SYM
bptjm-66	159	17	kg	kg	PROPN
bptjm-66	159	18	,	,	PUNCT
bptjm-66	159	19	meaning	mean	VERB
bptjm-66	159	20	pain	pain	NOUN
bptjm-66	159	21	was	be	AUX
bptjm-66	159	22	delayed	delay	VERB
bptjm-66	159	23	for	for	ADP
bptjm-66	159	24	about	about	ADV
bptjm-66	159	25	90	90	NUM
bptjm-66	159	26	minutes	minute	NOUN
bptjm-66	159	27	.	.	PUNCT
bptjm-66	160	1	just	just	ADV
bptjm-66	160	2	like	like	ADP
bptjm-66	160	3	zinc	zinc	NOUN
bptjm-66	160	4	,	,	PUNCT
bptjm-66	160	5	magnesium	magnesium	NOUN
bptjm-66	160	6	reduces	reduce	VERB
bptjm-66	160	7	the	the	DET
bptjm-66	160	8	need	need	NOUN
bptjm-66	160	9	for	for	ADP
bptjm-66	160	10	relaxant	relaxant	ADJ
bptjm-66	160	11	drugs	drug	NOUN
bptjm-66	160	12	,	,	PUNCT
bptjm-66	160	13	intraoperative	intraoperative	ADJ
bptjm-66	160	14	anesthetics	anesthetic	NOUN
bptjm-66	160	15	,	,	PUNCT
bptjm-66	160	16	and	and	CCONJ
bptjm-66	160	17	morphine	morphine	NOUN
bptjm-66	160	18	.	.	PUNCT
bptjm-66	161	1	figure	figure	NOUN
bptjm-66	161	2	1	1	NUM
bptjm-66	161	3	.	.	PUNCT
bptjm-66	161	4	results	result	NOUN
bptjm-66	161	5	from	from	ADP
bptjm-66	161	6	zinc	zinc	NOUN
bptjm-66	161	7	oxide	oxide	NOUN
bptjm-66	161	8	nanoparticles	nanoparticle	NOUN
bptjm-66	161	9	on	on	ADP
bptjm-66	161	10	rats	rat	NOUN
bptjm-66	161	11	3.3	3.3	NUM
bptjm-66	161	12	magnetite	magnetite	NOUN
bptjm-66	161	13	nanoparticles	nanoparticle	NOUN
bptjm-66	161	14	magnetic	magnetic	ADJ
bptjm-66	161	15	metal	metal	NOUN
bptjm-66	161	16	oxides	oxide	NOUN
bptjm-66	161	17	represent	represent	VERB
bptjm-66	161	18	a	a	DET
bptjm-66	161	19	distinct	distinct	ADJ
bptjm-66	161	20	class	class	NOUN
bptjm-66	161	21	of	of	ADP
bptjm-66	161	22	nanoparticles	nanoparticle	NOUN
bptjm-66	161	23	.	.	PUNCT
bptjm-66	162	1	ferromagnetic	ferromagnetic	ADJ
bptjm-66	162	2	compounds	compound	NOUN
bptjm-66	162	3	,	,	PUNCT
bptjm-66	162	4	including	include	VERB
bptjm-66	162	5	magnetite	magnetite	NOUN
bptjm-66	162	6	(	(	PUNCT
bptjm-66	162	7	fe3o4	fe3o4	PROPN
bptjm-66	162	8	)	)	PUNCT
bptjm-66	162	9	,	,	PUNCT
bptjm-66	162	10	have	have	AUX
bptjm-66	162	11	shown	show	VERB
bptjm-66	162	12	ferromagnetism	ferromagnetism	NOUN
bptjm-66	162	13	,	,	PUNCT
bptjm-66	162	14	meaning	mean	VERB
bptjm-66	162	15	that	that	SCONJ
bptjm-66	162	16	they	they	PRON
bptjm-66	162	17	readily	readily	ADV
bptjm-66	162	18	interact	interact	VERB
bptjm-66	162	19	with	with	ADP
bptjm-66	162	20	applied	apply	VERB
bptjm-66	162	21	external	external	ADJ
bptjm-66	162	22	magnetic	magnetic	ADJ
bptjm-66	162	23	fields	field	NOUN
bptjm-66	162	24	.	.	PUNCT
bptjm-66	163	1	similar	similar	ADJ
bptjm-66	163	2	to	to	ADP
bptjm-66	163	3	zinc	zinc	NOUN
bptjm-66	163	4	and	and	CCONJ
bptjm-66	163	5	magnesium	magnesium	NOUN
bptjm-66	163	6	oxide	oxide	NOUN
bptjm-66	163	7	,	,	PUNCT
bptjm-66	163	8	magnetite	magnetite	NOUN
bptjm-66	163	9	has	have	AUX
bptjm-66	163	10	demonstrated	demonstrate	VERB
bptjm-66	163	11	potential	potential	NOUN
bptjm-66	163	12	in	in	ADP
bptjm-66	163	13	directly	directly	ADV
bptjm-66	163	14	alleviating	alleviate	VERB
bptjm-66	163	15	pain	pain	NOUN
bptjm-66	163	16	.	.	PUNCT
bptjm-66	164	1	therapeutic	therapeutic	ADJ
bptjm-66	164	2	effects	effect	NOUN
bptjm-66	164	3	that	that	PRON
bptjm-66	164	4	the	the	DET
bptjm-66	164	5	nanoparticle	nanoparticle	NOUN
bptjm-66	164	6	possesses	possesse	NOUN
bptjm-66	164	7	were	be	AUX
bptjm-66	164	8	revealed	reveal	VERB
bptjm-66	164	9	by	by	ADP
bptjm-66	164	10	a	a	DET
bptjm-66	164	11	study	study	NOUN
bptjm-66	164	12	that	that	PRON
bptjm-66	164	13	concluded	conclude	VERB
bptjm-66	164	14	diminished	diminished	ADJ
bptjm-66	164	15	macrophage	macrophage	ADJ
bptjm-66	164	16	activity	activity	NOUN
bptjm-66	164	17	and	and	CCONJ
bptjm-66	164	18	diminished	diminish	VERB
bptjm-66	164	19	expression	expression	NOUN
bptjm-66	164	20	of	of	ADP
bptjm-66	164	21	inflammatory	inflammatory	ADJ
bptjm-66	164	22	biomarkers	biomarker	NOUN
bptjm-66	164	23	with	with	ADP
bptjm-66	164	24	the	the	DET
bptjm-66	164	25	treatment	treatment	NOUN
bptjm-66	164	26	of	of	ADP
bptjm-66	164	27	ferromagnetic	ferromagnetic	ADJ
bptjm-66	164	28	particles	particle	NOUN
bptjm-66	164	29	.	.	PUNCT
bptjm-66	165	1	however	however	ADV
bptjm-66	165	2	,	,	PUNCT
bptjm-66	165	3	the	the	DET
bptjm-66	165	4	most	most	ADV
bptjm-66	165	5	intriguing	intriguing	ADJ
bptjm-66	165	6	aspect	aspect	NOUN
bptjm-66	165	7	of	of	ADP
bptjm-66	165	8	magnetite	magnetite	NOUN
bptjm-66	165	9	is	be	AUX
bptjm-66	165	10	unveiled	unveil	VERB
bptjm-66	165	11	by	by	ADP
bptjm-66	165	12	its	its	PRON
bptjm-66	165	13	name	name	NOUN
bptjm-66	165	14	:	:	PUNCT
bptjm-66	165	15	magnetism	magnetism	NOUN
bptjm-66	165	16	.	.	PUNCT
bptjm-66	166	1	it	it	PRON
bptjm-66	166	2	has	have	AUX
bptjm-66	166	3	been	be	AUX
bptjm-66	166	4	widely	widely	ADV
bptjm-66	166	5	used	use	VERB
bptjm-66	166	6	as	as	ADP
bptjm-66	166	7	a	a	DET
bptjm-66	166	8	nanocarrier	nanocarrier	NOUN
bptjm-66	166	9	because	because	SCONJ
bptjm-66	166	10	of	of	ADP
bptjm-66	166	11	its	its	PRON
bptjm-66	166	12	capability	capability	NOUN
bptjm-66	166	13	to	to	PART
bptjm-66	166	14	control	control	VERB
bptjm-66	166	15	the	the	DET
bptjm-66	166	16	vesicle	vesicle	NOUN
bptjm-66	166	17	externally	externally	ADV
bptjm-66	166	18	through	through	ADP
bptjm-66	166	19	magnetic	magnetic	ADJ
bptjm-66	166	20	fields	field	NOUN
bptjm-66	166	21	.	.	PUNCT
bptjm-66	167	1	the	the	DET
bptjm-66	167	2	strong	strong	ADJ
bptjm-66	167	3	interaction	interaction	NOUN
bptjm-66	167	4	between	between	ADP
bptjm-66	167	5	the	the	DET
bptjm-66	167	6	nanoparticle	nanoparticle	NOUN
bptjm-66	167	7	and	and	CCONJ
bptjm-66	167	8	the	the	DET
bptjm-66	167	9	external	external	ADJ
bptjm-66	167	10	magnetic	magnetic	ADJ
bptjm-66	167	11	fields	field	NOUN
bptjm-66	167	12	enhances	enhance	VERB
bptjm-66	167	13	the	the	DET
bptjm-66	167	14	targeting	targeting	NOUN
bptjm-66	167	15	efficacy	efficacy	NOUN
bptjm-66	167	16	of	of	ADP
bptjm-66	167	17	this	this	DET
bptjm-66	167	18	method	method	NOUN
bptjm-66	167	19	,	,	PUNCT
bptjm-66	167	20	contributing	contribute	VERB
bptjm-66	167	21	to	to	ADP
bptjm-66	167	22	precise	precise	ADJ
bptjm-66	167	23	delivery	delivery	NOUN
bptjm-66	167	24	.	.	PUNCT
bptjm-66	168	1	just	just	ADV
bptjm-66	168	2	like	like	ADP
bptjm-66	168	3	zinc	zinc	NOUN
bptjm-66	168	4	oxide	oxide	NOUN
bptjm-66	168	5	nanoparticles	nanoparticle	NOUN
bptjm-66	168	6	,	,	PUNCT
bptjm-66	168	7	the	the	DET
bptjm-66	168	8	nanoparticles	nanoparticle	NOUN
bptjm-66	168	9	themselves	themselves	PRON
bptjm-66	168	10	hold	hold	VERB
bptjm-66	168	11	therapeutic	therapeutic	ADJ
bptjm-66	168	12	effects	effect	NOUN
bptjm-66	168	13	.	.	PUNCT
bptjm-66	169	1	berkeley	berkeley	PROPN
bptjm-66	169	2	pharma	pharma	PROPN
bptjm-66	169	3	tech	tech	PROPN
bptjm-66	169	4	journal	journal	NOUN
bptjm-66	169	5	of	of	ADP
bptjm-66	169	6	medicine	medicine	NOUN
bptjm-66	169	7	|	|	ADV
bptjm-66	169	8	11	11	NUM
bptjm-66	169	9	in	in	ADP
bptjm-66	169	10	a	a	DET
bptjm-66	169	11	mice	mouse	NOUN
bptjm-66	169	12	study28	study28	NOUN
bptjm-66	169	13	,	,	PUNCT
bptjm-66	169	14	iron	iron	NOUN
bptjm-66	169	15	oxide	oxide	NOUN
bptjm-66	169	16	nanoparticles	nanoparticle	NOUN
bptjm-66	169	17	were	be	AUX
bptjm-66	169	18	injected	inject	VERB
bptjm-66	169	19	,	,	PUNCT
bptjm-66	169	20	and	and	CCONJ
bptjm-66	169	21	the	the	DET
bptjm-66	169	22	prevalence	prevalence	NOUN
bptjm-66	169	23	of	of	ADP
bptjm-66	169	24	biomarkers	biomarker	NOUN
bptjm-66	169	25	was	be	AUX
bptjm-66	169	26	checked	check	VERB
bptjm-66	169	27	.	.	PUNCT
bptjm-66	170	1	these	these	DET
bptjm-66	170	2	biomarkers	biomarker	NOUN
bptjm-66	170	3	include	include	VERB
bptjm-66	170	4	reactive	reactive	ADJ
bptjm-66	170	5	oxygen	oxygen	NOUN
bptjm-66	170	6	species	specie	NOUN
bptjm-66	170	7	,	,	PUNCT
bptjm-66	170	8	cd68	cd68	PROPN
bptjm-66	170	9	,	,	PUNCT
bptjm-66	170	10	and	and	CCONJ
bptjm-66	170	11	mpo	mpo	PROPN
bptjm-66	170	12	(	(	PUNCT
bptjm-66	170	13	a	a	DET
bptjm-66	170	14	neutrophil	neutrophil	ADJ
bptjm-66	170	15	marker	marker	NOUN
bptjm-66	170	16	)	)	PUNCT
bptjm-66	170	17	.	.	PUNCT
bptjm-66	171	1	pain	pain	NOUN
bptjm-66	171	2	levels	level	NOUN
bptjm-66	171	3	were	be	AUX
bptjm-66	171	4	also	also	ADV
bptjm-66	171	5	measured	measure	VERB
bptjm-66	171	6	through	through	ADP
bptjm-66	171	7	von	von	PROPN
bptjm-66	171	8	frey	frey	PROPN
bptjm-66	171	9	filaments	filament	NOUN
bptjm-66	171	10	,	,	PUNCT
bptjm-66	171	11	a	a	DET
bptjm-66	171	12	band	band	NOUN
bptjm-66	171	13	that	that	PRON
bptjm-66	171	14	measures	measure	VERB
bptjm-66	171	15	mice	mouse	NOUN
bptjm-66	171	16	’s	’s	PART
bptjm-66	171	17	paw	paw	PROPN
bptjm-66	171	18	withdrawal	withdrawal	PROPN
bptjm-66	171	19	response	response	NOUN
bptjm-66	171	20	,	,	PUNCT
bptjm-66	171	21	an	an	DET
bptjm-66	171	22	indicator	indicator	NOUN
bptjm-66	171	23	of	of	ADP
bptjm-66	171	24	pain	pain	NOUN
bptjm-66	171	25	perception	perception	NOUN
bptjm-66	171	26	.	.	PUNCT
bptjm-66	172	1	after	after	ADP
bptjm-66	172	2	the	the	DET
bptjm-66	172	3	injection	injection	NOUN
bptjm-66	172	4	of	of	ADP
bptjm-66	172	5	treatment	treatment	NOUN
bptjm-66	172	6	into	into	ADP
bptjm-66	172	7	inflamed	inflamed	ADJ
bptjm-66	172	8	tissue	tissue	NOUN
bptjm-66	172	9	,	,	PUNCT
bptjm-66	172	10	there	there	PRON
bptjm-66	172	11	were	be	VERB
bptjm-66	172	12	signs	sign	NOUN
bptjm-66	172	13	of	of	ADP
bptjm-66	172	14	suppressed	suppress	VERB
bptjm-66	172	15	expression	expression	NOUN
bptjm-66	172	16	of	of	ADP
bptjm-66	172	17	the	the	DET
bptjm-66	172	18	previously	previously	ADV
bptjm-66	172	19	expressed	express	VERB
bptjm-66	172	20	proinflammatory	proinflammatory	ADJ
bptjm-66	172	21	biomarkers	biomarker	NOUN
bptjm-66	172	22	.	.	PUNCT
bptjm-66	173	1	further	far	ADV
bptjm-66	173	2	taking	take	VERB
bptjm-66	173	3	advantage	advantage	NOUN
bptjm-66	173	4	of	of	ADP
bptjm-66	173	5	the	the	DET
bptjm-66	173	6	magnetic	magnetic	ADJ
bptjm-66	173	7	properties	property	NOUN
bptjm-66	173	8	of	of	ADP
bptjm-66	173	9	magnetite	magnetite	NOUN
bptjm-66	173	10	,	,	PUNCT
bptjm-66	173	11	they	they	PRON
bptjm-66	173	12	are	be	AUX
bptjm-66	173	13	currently	currently	ADV
bptjm-66	173	14	being	be	AUX
bptjm-66	173	15	studied	study	VERB
bptjm-66	173	16	in	in	ADP
bptjm-66	173	17	the	the	DET
bptjm-66	173	18	field	field	NOUN
bptjm-66	173	19	of	of	ADP
bptjm-66	173	20	nanoparticle	nanoparticle	NOUN
bptjm-66	173	21	-	-	PUNCT
bptjm-66	173	22	induced	induce	VERB
bptjm-66	173	23	magnetic	magnetic	ADJ
bptjm-66	173	24	hyperthermia	hyperthermia	NOUN
bptjm-66	173	25	.	.	PUNCT
bptjm-66	174	1	bioactive	bioactive	ADJ
bptjm-66	174	2	glass	glass	NOUN
bptjm-66	174	3	doped	dope	VERB
bptjm-66	174	4	with	with	ADP
bptjm-66	174	5	magnetite	magnetite	NOUN
bptjm-66	174	6	nanoparticles	nanoparticle	NOUN
bptjm-66	174	7	can	can	AUX
bptjm-66	174	8	generate	generate	VERB
bptjm-66	174	9	heat	heat	NOUN
bptjm-66	174	10	in	in	ADP
bptjm-66	174	11	the	the	DET
bptjm-66	174	12	presence	presence	NOUN
bptjm-66	174	13	of	of	ADP
bptjm-66	174	14	an	an	DET
bptjm-66	174	15	alternating	alternate	VERB
bptjm-66	174	16	magnetic	magnetic	ADJ
bptjm-66	174	17	field29	field29	NOUN
bptjm-66	174	18	.	.	PUNCT
bptjm-66	175	1	when	when	SCONJ
bptjm-66	175	2	the	the	DET
bptjm-66	175	3	magnetic	magnetic	ADJ
bptjm-66	175	4	field	field	NOUN
bptjm-66	175	5	alternates	alternate	NOUN
bptjm-66	175	6	,	,	PUNCT
bptjm-66	175	7	the	the	DET
bptjm-66	175	8	magnetism	magnetism	NOUN
bptjm-66	175	9	of	of	ADP
bptjm-66	175	10	the	the	DET
bptjm-66	175	11	nanoparticle	nanoparticle	NOUN
bptjm-66	175	12	also	also	ADV
bptjm-66	175	13	alternates	alternate	VERB
bptjm-66	175	14	,	,	PUNCT
bptjm-66	175	15	but	but	CCONJ
bptjm-66	175	16	at	at	ADP
bptjm-66	175	17	a	a	DET
bptjm-66	175	18	delay	delay	NOUN
bptjm-66	175	19	,	,	PUNCT
bptjm-66	175	20	a	a	DET
bptjm-66	175	21	phenomenon	phenomenon	NOUN
bptjm-66	175	22	called	call	VERB
bptjm-66	175	23	magnetic	magnetic	ADJ
bptjm-66	175	24	hysteresis	hysteresis	NOUN
bptjm-66	175	25	.	.	PUNCT
bptjm-66	176	1	as	as	ADP
bptjm-66	176	2	a	a	DET
bptjm-66	176	3	result	result	NOUN
bptjm-66	176	4	,	,	PUNCT
bptjm-66	176	5	heat	heat	NOUN
bptjm-66	176	6	is	be	AUX
bptjm-66	176	7	capable	capable	ADJ
bptjm-66	176	8	of	of	ADP
bptjm-66	176	9	being	be	AUX
bptjm-66	176	10	generated	generate	VERB
bptjm-66	176	11	in	in	ADP
bptjm-66	176	12	a	a	DET
bptjm-66	176	13	highly	highly	ADV
bptjm-66	176	14	specific	specific	ADJ
bptjm-66	176	15	area	area	NOUN
bptjm-66	176	16	.	.	PUNCT
bptjm-66	177	1	3.4	3.4	NUM
bptjm-66	177	2	gold	gold	NOUN
bptjm-66	177	3	nanoparticles	nanoparticle	NOUN
bptjm-66	177	4	another	another	DET
bptjm-66	177	5	metallic	metallic	ADJ
bptjm-66	177	6	nanoparticle	nanoparticle	NOUN
bptjm-66	177	7	worth	worth	ADJ
bptjm-66	177	8	covering	cover	VERB
bptjm-66	177	9	is	be	AUX
bptjm-66	177	10	gold	gold	NOUN
bptjm-66	177	11	nanoparticles	nanoparticle	NOUN
bptjm-66	177	12	.	.	PUNCT
bptjm-66	178	1	currently	currently	ADV
bptjm-66	178	2	,	,	PUNCT
bptjm-66	178	3	at	at	ADP
bptjm-66	178	4	the	the	DET
bptjm-66	178	5	forefront	forefront	NOUN
bptjm-66	178	6	of	of	ADP
bptjm-66	178	7	cancer	cancer	NOUN
bptjm-66	178	8	research	research	NOUN
bptjm-66	178	9	,	,	PUNCT
bptjm-66	178	10	gold	gold	ADJ
bptjm-66	178	11	nanoparticles	nanoparticle	NOUN
bptjm-66	178	12	boast	boast	VERB
bptjm-66	178	13	a	a	DET
bptjm-66	178	14	myriad	myriad	NOUN
bptjm-66	178	15	of	of	ADP
bptjm-66	178	16	conformations	conformation	NOUN
bptjm-66	178	17	and	and	CCONJ
bptjm-66	178	18	high	high	ADJ
bptjm-66	178	19	membrane	membrane	NOUN
bptjm-66	178	20	customizability	customizability	NOUN
bptjm-66	178	21	.	.	PUNCT
bptjm-66	179	1	one	one	NUM
bptjm-66	179	2	of	of	ADP
bptjm-66	179	3	its	its	PRON
bptjm-66	179	4	most	most	ADV
bptjm-66	179	5	notable	notable	ADJ
bptjm-66	179	6	features	feature	NOUN
bptjm-66	179	7	is	be	AUX
bptjm-66	179	8	the	the	DET
bptjm-66	179	9	surface	surface	NOUN
bptjm-66	179	10	plasmon	plasmon	NOUN
bptjm-66	179	11	resonance	resonance	NOUN
bptjm-66	179	12	(	(	PUNCT
bptjm-66	179	13	spr	spr	INTJ
bptjm-66	179	14	)	)	PUNCT
bptjm-66	179	15	,	,	PUNCT
bptjm-66	179	16	a	a	DET
bptjm-66	179	17	phenomenon	phenomenon	NOUN
bptjm-66	179	18	that	that	PRON
bptjm-66	179	19	occurs	occur	VERB
bptjm-66	179	20	when	when	SCONJ
bptjm-66	179	21	electron	electron	NOUN
bptjm-66	179	22	oscillatory	oscillatory	ADJ
bptjm-66	179	23	frequencies	frequency	NOUN
bptjm-66	179	24	align	align	VERB
bptjm-66	179	25	with	with	ADP
bptjm-66	179	26	the	the	DET
bptjm-66	179	27	frequency	frequency	NOUN
bptjm-66	179	28	of	of	ADP
bptjm-66	179	29	incoming	incoming	ADJ
bptjm-66	179	30	light	light	NOUN
bptjm-66	179	31	,	,	PUNCT
bptjm-66	179	32	allowing	allow	VERB
bptjm-66	179	33	the	the	DET
bptjm-66	179	34	generation	generation	NOUN
bptjm-66	179	35	of	of	ADP
bptjm-66	179	36	a	a	DET
bptjm-66	179	37	magnetic	magnetic	ADJ
bptjm-66	179	38	field30	field30	NOUN
bptjm-66	179	39	.	.	PUNCT
bptjm-66	180	1	though	though	SCONJ
bptjm-66	180	2	showing	show	VERB
bptjm-66	180	3	great	great	ADJ
bptjm-66	180	4	promise	promise	NOUN
bptjm-66	180	5	,	,	PUNCT
bptjm-66	180	6	its	its	PRON
bptjm-66	180	7	toxicity	toxicity	NOUN
bptjm-66	180	8	must	must	AUX
bptjm-66	180	9	be	be	AUX
bptjm-66	180	10	considered	consider	VERB
bptjm-66	180	11	when	when	SCONJ
bptjm-66	180	12	evaluating	evaluate	VERB
bptjm-66	180	13	its	its	PRON
bptjm-66	180	14	efficacy	efficacy	NOUN
bptjm-66	180	15	.	.	PUNCT
bptjm-66	181	1	gold	gold	ADJ
bptjm-66	181	2	nanoparticles	nanoparticle	NOUN
bptjm-66	181	3	can	can	AUX
bptjm-66	181	4	alter	alter	VERB
bptjm-66	181	5	dna	dna	PROPN
bptjm-66	181	6	function	function	NOUN
bptjm-66	181	7	and	and	CCONJ
bptjm-66	181	8	bioaccumulate	bioaccumulate	NOUN
bptjm-66	181	9	.	.	PUNCT
bptjm-66	182	1	depending	depend	VERB
bptjm-66	182	2	on	on	ADP
bptjm-66	182	3	the	the	DET
bptjm-66	182	4	intended	intend	VERB
bptjm-66	182	5	application	application	NOUN
bptjm-66	182	6	,	,	PUNCT
bptjm-66	182	7	coatings	coating	NOUN
bptjm-66	182	8	added	add	VERB
bptjm-66	182	9	onto	onto	ADP
bptjm-66	182	10	these	these	DET
bptjm-66	182	11	nanoparticles	nanoparticle	NOUN
bptjm-66	182	12	,	,	PUNCT
bptjm-66	182	13	such	such	ADJ
bptjm-66	182	14	as	as	ADP
bptjm-66	182	15	folic	folic	ADJ
bptjm-66	182	16	acid	acid	NOUN
bptjm-66	182	17	,	,	PUNCT
bptjm-66	182	18	polyacrylamide	polyacrylamide	NOUN
bptjm-66	182	19	,	,	PUNCT
bptjm-66	182	20	polyvinylpyrrolidone	polyvinylpyrrolidone	NOUN
bptjm-66	182	21	,	,	PUNCT
bptjm-66	182	22	and	and	CCONJ
bptjm-66	182	23	polyacrylic	polyacrylic	ADJ
bptjm-66	182	24	acid	acid	PROPN
bptjm-66	182	25	can	can	AUX
bptjm-66	182	26	serve	serve	VERB
bptjm-66	182	27	to	to	ADP
bptjm-66	182	28	either	either	PRON
bptjm-66	182	29	mask	mask	VERB
bptjm-66	182	30	their	their	PRON
bptjm-66	182	31	cytotoxicity	cytotoxicity	NOUN
bptjm-66	182	32	or	or	CCONJ
bptjm-66	182	33	exploit	exploit	VERB
bptjm-66	182	34	it	it	PRON
bptjm-66	182	35	when	when	SCONJ
bptjm-66	182	36	targeting	target	VERB
bptjm-66	182	37	cancer	cancer	NOUN
bptjm-66	182	38	cells	cell	NOUN
bptjm-66	182	39	for	for	ADP
bptjm-66	182	40	treatment	treatment	NOUN
bptjm-66	182	41	.	.	PUNCT
bptjm-66	183	1	for	for	ADP
bptjm-66	183	2	instance	instance	NOUN
bptjm-66	183	3	,	,	PUNCT
bptjm-66	183	4	in	in	ADP
bptjm-66	183	5	a	a	DET
bptjm-66	183	6	study31	study31	NOUN
bptjm-66	183	7	that	that	PRON
bptjm-66	183	8	tested	test	VERB
bptjm-66	183	9	the	the	DET
bptjm-66	183	10	absorption	absorption	NOUN
bptjm-66	183	11	of	of	ADP
bptjm-66	183	12	gold	gold	ADJ
bptjm-66	183	13	nanoparticles	nanoparticle	NOUN
bptjm-66	183	14	,	,	PUNCT
bptjm-66	183	15	antibody	antibody	NOUN
bptjm-66	183	16	-	-	PUNCT
bptjm-66	183	17	modified	modify	VERB
bptjm-66	183	18	gold	gold	NOUN
bptjm-66	183	19	nanoparticles	nanoparticle	NOUN
bptjm-66	183	20	demonstrated	demonstrate	VERB
bptjm-66	183	21	a	a	DET
bptjm-66	183	22	600	600	NUM
bptjm-66	183	23	%	%	NOUN
bptjm-66	183	24	increased	increase	VERB
bptjm-66	183	25	retention	retention	NOUN
bptjm-66	183	26	to	to	ADP
bptjm-66	183	27	tumor	tumor	NOUN
bptjm-66	183	28	cells	cell	NOUN
bptjm-66	183	29	,	,	PUNCT
bptjm-66	183	30	allowing	allow	VERB
bptjm-66	183	31	greater	great	ADJ
bptjm-66	183	32	release	release	NOUN
bptjm-66	183	33	of	of	ADP
bptjm-66	183	34	cytotoxicity	cytotoxicity	NOUN
bptjm-66	183	35	into	into	ADP
bptjm-66	183	36	the	the	DET
bptjm-66	183	37	cell	cell	NOUN
bptjm-66	183	38	.	.	PUNCT
bptjm-66	184	1	looking	look	VERB
bptjm-66	184	2	into	into	ADP
bptjm-66	184	3	the	the	DET
bptjm-66	184	4	therapies	therapy	NOUN
bptjm-66	184	5	driven	drive	VERB
bptjm-66	184	6	by	by	ADP
bptjm-66	184	7	gold	gold	ADJ
bptjm-66	184	8	nanoparticles	nanoparticle	NOUN
bptjm-66	184	9	,	,	PUNCT
bptjm-66	184	10	photothermal	photothermal	ADJ
bptjm-66	184	11	and	and	CCONJ
bptjm-66	184	12	radiofrequency	radiofrequency	NOUN
bptjm-66	184	13	therapy	therapy	NOUN
bptjm-66	184	14	stand	stand	VERB
bptjm-66	184	15	as	as	ADP
bptjm-66	184	16	promising	promise	VERB
bptjm-66	184	17	candidates	candidate	NOUN
bptjm-66	184	18	.	.	PUNCT
bptjm-66	185	1	as	as	SCONJ
bptjm-66	185	2	previously	previously	ADV
bptjm-66	185	3	mentioned	mention	VERB
bptjm-66	185	4	,	,	PUNCT
bptjm-66	185	5	the	the	DET
bptjm-66	185	6	ability	ability	NOUN
bptjm-66	185	7	of	of	ADP
bptjm-66	185	8	nanoparticles	nanoparticle	NOUN
bptjm-66	185	9	to	to	PART
bptjm-66	185	10	absorb	absorb	VERB
bptjm-66	185	11	and	and	CCONJ
bptjm-66	185	12	scatter	scatter	VERB
bptjm-66	185	13	electromagnetic	electromagnetic	ADJ
bptjm-66	185	14	radiation	radiation	NOUN
bptjm-66	185	15	has	have	AUX
bptjm-66	185	16	captured	capture	VERB
bptjm-66	185	17	significant	significant	ADJ
bptjm-66	185	18	interest	interest	NOUN
bptjm-66	185	19	in	in	ADP
bptjm-66	185	20	the	the	DET
bptjm-66	185	21	realm	realm	NOUN
bptjm-66	185	22	of	of	ADP
bptjm-66	185	23	berkeley	berkeley	PROPN
bptjm-66	185	24	pharma	pharma	PROPN
bptjm-66	185	25	tech	tech	NOUN
bptjm-66	185	26	journal	journal	NOUN
bptjm-66	185	27	of	of	ADP
bptjm-66	185	28	medicine	medicine	NOUN
bptjm-66	185	29	|	|	ADV
bptjm-66	185	30	12	12	NUM
bptjm-66	185	31	photothermal	photothermal	ADJ
bptjm-66	185	32	therapy	therapy	NOUN
bptjm-66	185	33	.	.	PUNCT
bptjm-66	186	1	the	the	DET
bptjm-66	186	2	application	application	NOUN
bptjm-66	186	3	of	of	ADP
bptjm-66	186	4	this	this	DET
bptjm-66	186	5	phenomenon	phenomenon	NOUN
bptjm-66	186	6	has	have	AUX
bptjm-66	186	7	been	be	AUX
bptjm-66	186	8	studied	study	VERB
bptjm-66	186	9	in	in	ADP
bptjm-66	186	10	localized	localized	ADJ
bptjm-66	186	11	hyperthermia	hyperthermia	NOUN
bptjm-66	186	12	,	,	PUNCT
bptjm-66	186	13	as	as	ADV
bptjm-66	186	14	well	well	ADV
bptjm-66	186	15	as	as	ADP
bptjm-66	186	16	radiofrequency	radiofrequency	NOUN
bptjm-66	186	17	therapy	therapy	NOUN
bptjm-66	186	18	,	,	PUNCT
bptjm-66	186	19	as	as	SCONJ
bptjm-66	186	20	its	its	PRON
bptjm-66	186	21	great	great	ADJ
bptjm-66	186	22	specificity	specificity	NOUN
bptjm-66	186	23	and	and	CCONJ
bptjm-66	186	24	morphology	morphology	NOUN
bptjm-66	186	25	control	control	NOUN
bptjm-66	186	26	have	have	AUX
bptjm-66	186	27	contributed	contribute	VERB
bptjm-66	186	28	to	to	ADP
bptjm-66	186	29	great	great	ADJ
bptjm-66	186	30	levels	level	NOUN
bptjm-66	186	31	of	of	ADP
bptjm-66	186	32	localization	localization	NOUN
bptjm-66	186	33	.	.	PUNCT
bptjm-66	187	1	its	its	PRON
bptjm-66	187	2	impact	impact	NOUN
bptjm-66	187	3	has	have	AUX
bptjm-66	187	4	also	also	ADV
bptjm-66	187	5	been	be	AUX
bptjm-66	187	6	seen	see	VERB
bptjm-66	187	7	in	in	ADP
bptjm-66	187	8	neurodegenerative	neurodegenerative	ADJ
bptjm-66	187	9	disorders	disorder	NOUN
bptjm-66	187	10	,	,	PUNCT
bptjm-66	187	11	such	such	ADJ
bptjm-66	187	12	as	as	ADP
bptjm-66	187	13	parkinson	parkinson	NOUN
bptjm-66	187	14	’s	’s	PART
bptjm-66	187	15	disease	disease	NOUN
bptjm-66	187	16	,	,	PUNCT
bptjm-66	187	17	multiple	multiple	ADJ
bptjm-66	187	18	sclerosis	sclerosis	NOUN
bptjm-66	187	19	,	,	PUNCT
bptjm-66	187	20	and	and	CCONJ
bptjm-66	187	21	lou	lou	PROPN
bptjm-66	187	22	gehrig	gehrig	PROPN
bptjm-66	187	23	’s	’s	PART
bptjm-66	187	24	disease	disease	NOUN
bptjm-66	187	25	.	.	PUNCT
bptjm-66	188	1	the	the	DET
bptjm-66	188	2	commonality	commonality	NOUN
bptjm-66	188	3	amongst	amongst	ADP
bptjm-66	188	4	these	these	DET
bptjm-66	188	5	painful	painful	ADJ
bptjm-66	188	6	illnesses	illness	NOUN
bptjm-66	188	7	includes	include	VERB
bptjm-66	188	8	the	the	DET
bptjm-66	188	9	decline	decline	NOUN
bptjm-66	188	10	of	of	ADP
bptjm-66	188	11	the	the	DET
bptjm-66	188	12	nad+/nadh	nad+/nadh	NOUN
bptjm-66	188	13	ratio	ratio	NOUN
bptjm-66	188	14	in	in	ADP
bptjm-66	188	15	the	the	DET
bptjm-66	188	16	brain	brain	NOUN
bptjm-66	188	17	.	.	PUNCT
bptjm-66	189	1	reversing	reverse	VERB
bptjm-66	189	2	this	this	DET
bptjm-66	189	3	energy	energy	NOUN
bptjm-66	189	4	deficit	deficit	NOUN
bptjm-66	189	5	promises	promise	VERB
bptjm-66	189	6	slower	slow	ADJ
bptjm-66	189	7	neurodegenerative	neurodegenerative	ADJ
bptjm-66	189	8	decline	decline	NOUN
bptjm-66	189	9	and	and	CCONJ
bptjm-66	189	10	even	even	ADV
bptjm-66	189	11	partial	partial	ADJ
bptjm-66	189	12	recovery	recovery	NOUN
bptjm-66	189	13	.	.	PUNCT
bptjm-66	190	1	in	in	ADP
bptjm-66	190	2	the	the	DET
bptjm-66	190	3	phase	phase	NOUN
bptjm-66	190	4	2	2	NUM
bptjm-66	190	5	clinical	clinical	ADJ
bptjm-66	190	6	trial	trial	NOUN
bptjm-66	190	7	conducted	conduct	VERB
bptjm-66	190	8	in	in	ADP
bptjm-66	190	9	202432	202432	NUM
bptjm-66	190	10	,	,	PUNCT
bptjm-66	190	11	gold	gold	ADJ
bptjm-66	190	12	nanoparticles	nanoparticle	NOUN
bptjm-66	190	13	demonstrated	demonstrate	VERB
bptjm-66	190	14	their	their	PRON
bptjm-66	190	15	capability	capability	NOUN
bptjm-66	190	16	to	to	PART
bptjm-66	190	17	improve	improve	VERB
bptjm-66	190	18	this	this	DET
bptjm-66	190	19	nad+/nadh	nad+/nadh	NOUN
bptjm-66	190	20	balance	balance	NOUN
bptjm-66	190	21	.	.	PUNCT
bptjm-66	191	1	11	11	NUM
bptjm-66	191	2	participants	participant	NOUN
bptjm-66	191	3	with	with	ADP
bptjm-66	191	4	relapsing	relapse	VERB
bptjm-66	191	5	multiple	multiple	ADJ
bptjm-66	191	6	sclerosis	sclerosis	NOUN
bptjm-66	191	7	and	and	CCONJ
bptjm-66	191	8	13	13	NUM
bptjm-66	191	9	with	with	ADP
bptjm-66	191	10	parkinson	parkinson	NOUN
bptjm-66	191	11	’s	’s	PART
bptjm-66	191	12	disease	disease	NOUN
bptjm-66	191	13	were	be	AUX
bptjm-66	191	14	the	the	DET
bptjm-66	191	15	subjects	subject	NOUN
bptjm-66	191	16	of	of	ADP
bptjm-66	191	17	this	this	DET
bptjm-66	191	18	clinical	clinical	ADJ
bptjm-66	191	19	trial	trial	NOUN
bptjm-66	191	20	and	and	CCONJ
bptjm-66	191	21	took	take	VERB
bptjm-66	191	22	cnm	cnm	PROPN
bptjm-66	191	23	-	-	PUNCT
bptjm-66	191	24	au8	au8	PROPN
bptjm-66	191	25	(	(	PUNCT
bptjm-66	191	26	the	the	DET
bptjm-66	191	27	gold	gold	NOUN
bptjm-66	191	28	nanoparticle	nanoparticle	NOUN
bptjm-66	191	29	-	-	PUNCT
bptjm-66	191	30	based	base	VERB
bptjm-66	191	31	therapeutic	therapeutic	ADJ
bptjm-66	191	32	agent	agent	NOUN
bptjm-66	191	33	)	)	PUNCT
bptjm-66	191	34	for	for	ADP
bptjm-66	191	35	12	12	NUM
bptjm-66	191	36	weeks	week	NOUN
bptjm-66	191	37	.	.	PUNCT
bptjm-66	192	1	the	the	DET
bptjm-66	192	2	result	result	NOUN
bptjm-66	192	3	included	include	VERB
bptjm-66	192	4	an	an	DET
bptjm-66	192	5	average	average	NOUN
bptjm-66	192	6	of	of	ADP
bptjm-66	192	7	10.4	10.4	NUM
bptjm-66	192	8	%	%	NOUN
bptjm-66	192	9	improvement	improvement	NOUN
bptjm-66	192	10	in	in	ADP
bptjm-66	192	11	nad+/nadh	nad+/nadh	NOUN
bptjm-66	192	12	ratios	ratio	NOUN
bptjm-66	192	13	.	.	PUNCT
bptjm-66	193	1	further	far	ADV
bptjm-66	193	2	validated	validated	ADJ
bptjm-66	193	3	testing	testing	NOUN
bptjm-66	193	4	was	be	AUX
bptjm-66	193	5	performed	perform	VERB
bptjm-66	193	6	to	to	PART
bptjm-66	193	7	test	test	VERB
bptjm-66	193	8	the	the	DET
bptjm-66	193	9	motor	motor	NOUN
bptjm-66	193	10	skills	skill	NOUN
bptjm-66	193	11	of	of	ADP
bptjm-66	193	12	these	these	DET
bptjm-66	193	13	patients	patient	NOUN
bptjm-66	193	14	and	and	CCONJ
bptjm-66	193	15	improved	improve	VERB
bptjm-66	193	16	motor	motor	NOUN
bptjm-66	193	17	skills	skill	NOUN
bptjm-66	193	18	were	be	AUX
bptjm-66	193	19	demonstrated	demonstrate	VERB
bptjm-66	193	20	by	by	ADP
bptjm-66	193	21	the	the	DET
bptjm-66	193	22	patients	patient	NOUN
bptjm-66	193	23	.	.	PUNCT
bptjm-66	194	1	without	without	ADP
bptjm-66	194	2	diagnosing	diagnose	VERB
bptjm-66	194	3	any	any	DET
bptjm-66	194	4	adverse	adverse	ADJ
bptjm-66	194	5	effects	effect	NOUN
bptjm-66	194	6	of	of	ADP
bptjm-66	194	7	this	this	DET
bptjm-66	194	8	treatment	treatment	NOUN
bptjm-66	194	9	,	,	PUNCT
bptjm-66	194	10	the	the	DET
bptjm-66	194	11	gold	gold	NOUN
bptjm-66	194	12	nanoparticles	nanoparticle	NOUN
bptjm-66	194	13	have	have	AUX
bptjm-66	194	14	cemented	cement	VERB
bptjm-66	194	15	themselves	themselves	PRON
bptjm-66	194	16	as	as	ADP
bptjm-66	194	17	a	a	DET
bptjm-66	194	18	promising	promising	ADJ
bptjm-66	194	19	candidate	candidate	NOUN
bptjm-66	194	20	for	for	ADP
bptjm-66	194	21	neurodegenerative	neurodegenerative	ADJ
bptjm-66	194	22	disorders	disorder	NOUN
bptjm-66	194	23	.	.	PUNCT
bptjm-66	195	1	the	the	DET
bptjm-66	195	2	next	next	ADJ
bptjm-66	195	3	class	class	NOUN
bptjm-66	195	4	of	of	ADP
bptjm-66	195	5	nanoparticles	nanoparticle	NOUN
bptjm-66	195	6	this	this	DET
bptjm-66	195	7	review	review	NOUN
bptjm-66	195	8	article	article	NOUN
bptjm-66	195	9	will	will	AUX
bptjm-66	195	10	be	be	AUX
bptjm-66	195	11	covering	cover	VERB
bptjm-66	195	12	includes	include	VERB
bptjm-66	195	13	nanocarriers	nanocarrier	NOUN
bptjm-66	195	14	,	,	PUNCT
bptjm-66	195	15	one	one	NUM
bptjm-66	195	16	of	of	ADP
bptjm-66	195	17	the	the	DET
bptjm-66	195	18	most	most	ADV
bptjm-66	195	19	active	active	ADJ
bptjm-66	195	20	areas	area	NOUN
bptjm-66	195	21	of	of	ADP
bptjm-66	195	22	research	research	NOUN
bptjm-66	195	23	in	in	ADP
bptjm-66	195	24	nanotechnology	nanotechnology	NOUN
bptjm-66	195	25	.	.	PUNCT
bptjm-66	196	1	the	the	DET
bptjm-66	196	2	capability	capability	NOUN
bptjm-66	196	3	to	to	ADP
bptjm-66	196	4	fine	fine	ADJ
bptjm-66	196	5	-	-	PUNCT
bptjm-66	196	6	tune	tune	NOUN
bptjm-66	196	7	the	the	DET
bptjm-66	196	8	solubility	solubility	NOUN
bptjm-66	196	9	and	and	CCONJ
bptjm-66	196	10	mimic	mimic	ADJ
bptjm-66	196	11	human	human	ADJ
bptjm-66	196	12	cells	cell	NOUN
bptjm-66	196	13	grants	grant	VERB
bptjm-66	196	14	them	they	PRON
bptjm-66	196	15	easy	easy	ADJ
bptjm-66	196	16	entry	entry	NOUN
bptjm-66	196	17	into	into	ADP
bptjm-66	196	18	specific	specific	ADJ
bptjm-66	196	19	cells	cell	NOUN
bptjm-66	196	20	,	,	PUNCT
bptjm-66	196	21	while	while	SCONJ
bptjm-66	196	22	their	their	PRON
bptjm-66	196	23	ability	ability	NOUN
bptjm-66	196	24	to	to	PART
bptjm-66	196	25	vary	vary	VERB
bptjm-66	196	26	delivery	delivery	NOUN
bptjm-66	196	27	mechanisms	mechanism	NOUN
bptjm-66	196	28	based	base	VERB
bptjm-66	196	29	on	on	ADP
bptjm-66	196	30	environmental	environmental	ADJ
bptjm-66	196	31	factors	factor	NOUN
bptjm-66	196	32	ensures	ensure	VERB
bptjm-66	196	33	controlled	control	VERB
bptjm-66	196	34	and	and	CCONJ
bptjm-66	196	35	precise	precise	ADJ
bptjm-66	196	36	drug	drug	NOUN
bptjm-66	196	37	release	release	NOUN
bptjm-66	196	38	.	.	PUNCT
bptjm-66	197	1	by	by	ADP
bptjm-66	197	2	doping	dope	VERB
bptjm-66	197	3	the	the	DET
bptjm-66	197	4	nanoparticles	nanoparticle	NOUN
bptjm-66	197	5	with	with	ADP
bptjm-66	197	6	various	various	ADJ
bptjm-66	197	7	membranes	membrane	NOUN
bptjm-66	197	8	or	or	CCONJ
bptjm-66	197	9	certain	certain	ADJ
bptjm-66	197	10	receptors	receptor	NOUN
bptjm-66	197	11	,	,	PUNCT
bptjm-66	197	12	there	there	PRON
bptjm-66	197	13	are	be	VERB
bptjm-66	197	14	many	many	ADJ
bptjm-66	197	15	ways	way	NOUN
bptjm-66	197	16	to	to	PART
bptjm-66	197	17	specify	specify	VERB
bptjm-66	197	18	the	the	DET
bptjm-66	197	19	targeted	target	VERB
bptjm-66	197	20	location	location	NOUN
bptjm-66	197	21	of	of	ADP
bptjm-66	197	22	the	the	DET
bptjm-66	197	23	cell	cell	NOUN
bptjm-66	197	24	.	.	PUNCT
bptjm-66	198	1	beyond	beyond	ADP
bptjm-66	198	2	their	their	PRON
bptjm-66	198	3	ability	ability	NOUN
bptjm-66	198	4	to	to	PART
bptjm-66	198	5	precisely	precisely	ADV
bptjm-66	198	6	target	target	VERB
bptjm-66	198	7	cells	cell	NOUN
bptjm-66	198	8	,	,	PUNCT
bptjm-66	198	9	their	their	PRON
bptjm-66	198	10	modifications	modification	NOUN
bptjm-66	198	11	enhance	enhance	VERB
bptjm-66	198	12	drug	drug	NOUN
bptjm-66	198	13	stability	stability	NOUN
bptjm-66	198	14	and	and	CCONJ
bptjm-66	198	15	cellular	cellular	ADJ
bptjm-66	198	16	compatibility	compatibility	NOUN
bptjm-66	198	17	.	.	PUNCT
bptjm-66	199	1	with	with	ADP
bptjm-66	199	2	high	high	ADJ
bptjm-66	199	3	modification	modification	NOUN
bptjm-66	199	4	potential	potential	NOUN
bptjm-66	199	5	,	,	PUNCT
bptjm-66	199	6	nanocarriers	nanocarrier	NOUN
bptjm-66	199	7	hold	hold	VERB
bptjm-66	199	8	immense	immense	ADJ
bptjm-66	199	9	promise	promise	NOUN
bptjm-66	199	10	for	for	ADP
bptjm-66	199	11	personalized	personalized	ADJ
bptjm-66	199	12	medicine	medicine	NOUN
bptjm-66	199	13	and	and	CCONJ
bptjm-66	199	14	theranostic	theranostic	ADJ
bptjm-66	199	15	applications	application	NOUN
bptjm-66	199	16	.	.	PUNCT
bptjm-66	200	1	we	we	PRON
bptjm-66	200	2	will	will	AUX
bptjm-66	200	3	be	be	AUX
bptjm-66	200	4	taking	take	VERB
bptjm-66	200	5	a	a	DET
bptjm-66	200	6	look	look	NOUN
bptjm-66	200	7	at	at	ADP
bptjm-66	200	8	a	a	DET
bptjm-66	200	9	few	few	ADJ
bptjm-66	200	10	nanocarriers	nanocarrier	NOUN
bptjm-66	200	11	that	that	PRON
bptjm-66	200	12	are	be	AUX
bptjm-66	200	13	currently	currently	ADV
bptjm-66	200	14	being	be	AUX
bptjm-66	200	15	researched	research	VERB
bptjm-66	200	16	in	in	ADP
bptjm-66	200	17	the	the	DET
bptjm-66	200	18	field	field	NOUN
bptjm-66	200	19	of	of	ADP
bptjm-66	200	20	nanotechnology33	nanotechnology33	NOUN
bptjm-66	200	21	.	.	PUNCT
bptjm-66	201	1	3.5	3.5	NUM
bptjm-66	201	2	liposomes	liposome	NOUN
bptjm-66	201	3	liposomes	liposome	NOUN
bptjm-66	201	4	are	be	AUX
bptjm-66	201	5	mainly	mainly	ADV
bptjm-66	201	6	composed	compose	VERB
bptjm-66	201	7	of	of	ADP
bptjm-66	201	8	cholesterols	cholesterol	NOUN
bptjm-66	201	9	and	and	CCONJ
bptjm-66	201	10	phospholipids	phospholipid	NOUN
bptjm-66	201	11	,	,	PUNCT
bptjm-66	201	12	boasting	boast	VERB
bptjm-66	201	13	great	great	ADJ
bptjm-66	201	14	biocompatibility	biocompatibility	NOUN
bptjm-66	201	15	,	,	PUNCT
bptjm-66	201	16	biodegradability	biodegradability	NOUN
bptjm-66	201	17	,	,	PUNCT
bptjm-66	201	18	high	high	ADJ
bptjm-66	201	19	loading	loading	NOUN
bptjm-66	201	20	capacity	capacity	NOUN
bptjm-66	201	21	,	,	PUNCT
bptjm-66	201	22	and	and	CCONJ
bptjm-66	201	23	permeability	permeability	NOUN
bptjm-66	201	24	.	.	PUNCT
bptjm-66	202	1	over	over	ADP
bptjm-66	202	2	the	the	DET
bptjm-66	202	3	past	past	ADJ
bptjm-66	202	4	decades	decade	NOUN
bptjm-66	202	5	,	,	PUNCT
bptjm-66	202	6	liposomes	liposome	NOUN
bptjm-66	202	7	have	have	AUX
bptjm-66	202	8	gradually	gradually	ADV
bptjm-66	202	9	been	be	AUX
bptjm-66	202	10	berkeley	berkeley	PROPN
bptjm-66	202	11	pharma	pharma	PROPN
bptjm-66	202	12	tech	tech	NOUN
bptjm-66	202	13	journal	journal	NOUN
bptjm-66	202	14	of	of	ADP
bptjm-66	202	15	medicine	medicine	NOUN
bptjm-66	202	16	|	|	ADV
bptjm-66	202	17	13	13	NUM
bptjm-66	202	18	improved	improve	VERB
bptjm-66	202	19	to	to	PART
bptjm-66	202	20	localize	localize	VERB
bptjm-66	202	21	more	more	ADV
bptjm-66	202	22	precisely	precisely	ADV
bptjm-66	202	23	,	,	PUNCT
bptjm-66	202	24	with	with	ADP
bptjm-66	202	25	improved	improved	ADJ
bptjm-66	202	26	responsiveness	responsiveness	NOUN
bptjm-66	202	27	to	to	ADP
bptjm-66	202	28	ph	ph	NOUN
bptjm-66	202	29	and	and	CCONJ
bptjm-66	202	30	temperature	temperature	NOUN
bptjm-66	202	31	as	as	ADP
bptjm-66	202	32	conditions	condition	NOUN
bptjm-66	202	33	,	,	PUNCT
bptjm-66	202	34	though	though	SCONJ
bptjm-66	202	35	they	they	PRON
bptjm-66	202	36	still	still	ADV
bptjm-66	202	37	encounter	encounter	VERB
bptjm-66	202	38	issues	issue	NOUN
bptjm-66	202	39	.	.	PUNCT
bptjm-66	203	1	some	some	PRON
bptjm-66	203	2	of	of	ADP
bptjm-66	203	3	its	its	PRON
bptjm-66	203	4	applications	application	NOUN
bptjm-66	203	5	have	have	AUX
bptjm-66	203	6	been	be	AUX
bptjm-66	203	7	heavily	heavily	ADV
bptjm-66	203	8	explored	explore	VERB
bptjm-66	203	9	in	in	ADP
bptjm-66	203	10	co	co	NOUN
bptjm-66	203	11	-	-	NOUN
bptjm-66	203	12	morbidities	morbidity	NOUN
bptjm-66	203	13	with	with	ADP
bptjm-66	203	14	chronic	chronic	ADJ
bptjm-66	203	15	pain	pain	NOUN
bptjm-66	203	16	,	,	PUNCT
bptjm-66	203	17	including	include	VERB
bptjm-66	203	18	cancer	cancer	NOUN
bptjm-66	203	19	.	.	PUNCT
bptjm-66	204	1	in	in	ADP
bptjm-66	204	2	a	a	DET
bptjm-66	204	3	clinical	clinical	ADJ
bptjm-66	204	4	study34	study34	NOUN
bptjm-66	204	5	conducted	conduct	VERB
bptjm-66	204	6	in	in	ADP
bptjm-66	204	7	2022	2022	NUM
bptjm-66	204	8	on	on	ADP
bptjm-66	204	9	the	the	DET
bptjm-66	204	10	efficacy	efficacy	NOUN
bptjm-66	204	11	of	of	ADP
bptjm-66	204	12	liposomes	liposome	NOUN
bptjm-66	204	13	in	in	ADP
bptjm-66	204	14	children	child	NOUN
bptjm-66	204	15	’s	’s	PART
bptjm-66	204	16	anticancer	anticancer	NOUN
bptjm-66	204	17	therapy	therapy	NOUN
bptjm-66	204	18	74	74	NUM
bptjm-66	204	19	trials	trial	NOUN
bptjm-66	204	20	were	be	AUX
bptjm-66	204	21	conducted	conduct	VERB
bptjm-66	204	22	with	with	ADP
bptjm-66	204	23	70	70	NUM
bptjm-66	204	24	being	be	AUX
bptjm-66	204	25	intervention	intervention	NOUN
bptjm-66	204	26	trials	trial	NOUN
bptjm-66	204	27	and	and	CCONJ
bptjm-66	204	28	4	4	NUM
bptjm-66	204	29	being	be	AUX
bptjm-66	204	30	observational	observational	ADJ
bptjm-66	204	31	trials	trial	NOUN
bptjm-66	204	32	,	,	PUNCT
bptjm-66	204	33	with	with	ADP
bptjm-66	204	34	28.6	28.6	NUM
bptjm-66	204	35	%	%	NOUN
bptjm-66	204	36	being	be	AUX
bptjm-66	204	37	in	in	ADP
bptjm-66	204	38	phase	phase	NOUN
bptjm-66	204	39	3	3	NUM
bptjm-66	204	40	trials	trial	NOUN
bptjm-66	204	41	,	,	PUNCT
bptjm-66	204	42	30.0	30.0	NUM
bptjm-66	204	43	%	%	NOUN
bptjm-66	204	44	in	in	ADP
bptjm-66	204	45	phase	phase	NOUN
bptjm-66	204	46	1	1	NUM
bptjm-66	204	47	trials	trial	NOUN
bptjm-66	204	48	,	,	PUNCT
bptjm-66	204	49	and	and	CCONJ
bptjm-66	204	50	24.3	24.3	NUM
bptjm-66	204	51	%	%	NOUN
bptjm-66	204	52	in	in	ADP
bptjm-66	204	53	phase	phase	NOUN
bptjm-66	204	54	2	2	NUM
bptjm-66	204	55	trials	trial	NOUN
bptjm-66	204	56	.	.	PUNCT
bptjm-66	205	1	in	in	ADP
bptjm-66	205	2	total	total	ADJ
bptjm-66	205	3	,	,	PUNCT
bptjm-66	205	4	17	17	NUM
bptjm-66	205	5	liposomal	liposomal	ADJ
bptjm-66	205	6	drugs	drug	NOUN
bptjm-66	205	7	for	for	ADP
bptjm-66	205	8	123	123	NUM
bptjm-66	205	9	types	type	NOUN
bptjm-66	205	10	of	of	ADP
bptjm-66	205	11	cancer	cancer	NOUN
bptjm-66	205	12	were	be	AUX
bptjm-66	205	13	investigated	investigate	VERB
bptjm-66	205	14	,	,	PUNCT
bptjm-66	205	15	consisting	consist	VERB
bptjm-66	205	16	mainly	mainly	ADV
bptjm-66	205	17	of	of	ADP
bptjm-66	205	18	organic	organic	ADJ
bptjm-66	205	19	chemicals	chemical	NOUN
bptjm-66	205	20	.	.	PUNCT
bptjm-66	206	1	of	of	ADP
bptjm-66	206	2	these	these	DET
bptjm-66	206	3	cancers	cancer	NOUN
bptjm-66	206	4	,	,	PUNCT
bptjm-66	206	5	the	the	DET
bptjm-66	206	6	highest	high	ADJ
bptjm-66	206	7	proportion	proportion	NOUN
bptjm-66	206	8	was	be	AUX
bptjm-66	206	9	leukemia	leukemia	NOUN
bptjm-66	206	10	(	(	PUNCT
bptjm-66	206	11	15.4	15.4	NUM
bptjm-66	206	12	%	%	NOUN
bptjm-66	206	13	)	)	PUNCT
bptjm-66	206	14	,	,	PUNCT
bptjm-66	206	15	followed	follow	VERB
bptjm-66	206	16	by	by	ADP
bptjm-66	206	17	lymphoma	lymphoma	NOUN
bptjm-66	206	18	(	(	PUNCT
bptjm-66	206	19	9.8	9.8	NUM
bptjm-66	206	20	%	%	NOUN
bptjm-66	206	21	)	)	PUNCT
bptjm-66	206	22	and	and	CCONJ
bptjm-66	206	23	ovarian	ovarian	ADJ
bptjm-66	206	24	cancer	cancer	NOUN
bptjm-66	206	25	(	(	PUNCT
bptjm-66	206	26	8.9	8.9	NUM
bptjm-66	206	27	%	%	NOUN
bptjm-66	206	28	)	)	PUNCT
bptjm-66	206	29	.	.	PUNCT
bptjm-66	207	1	it	it	PRON
bptjm-66	207	2	is	be	AUX
bptjm-66	207	3	worth	worth	ADJ
bptjm-66	207	4	noting	note	VERB
bptjm-66	207	5	that	that	SCONJ
bptjm-66	207	6	accurate	accurate	ADJ
bptjm-66	207	7	statistical	statistical	ADJ
bptjm-66	207	8	masking	masking	NOUN
bptjm-66	207	9	is	be	AUX
bptjm-66	207	10	required	require	VERB
bptjm-66	207	11	to	to	PART
bptjm-66	207	12	produce	produce	VERB
bptjm-66	207	13	accurate	accurate	ADJ
bptjm-66	207	14	results	result	NOUN
bptjm-66	207	15	,	,	PUNCT
bptjm-66	207	16	and	and	CCONJ
bptjm-66	207	17	only	only	ADV
bptjm-66	207	18	30	30	NUM
bptjm-66	207	19	%	%	NOUN
bptjm-66	207	20	of	of	ADP
bptjm-66	207	21	the	the	DET
bptjm-66	207	22	data	datum	NOUN
bptjm-66	207	23	collected	collect	VERB
bptjm-66	207	24	was	be	AUX
bptjm-66	207	25	properly	properly	ADV
bptjm-66	207	26	masked	mask	VERB
bptjm-66	207	27	.	.	PUNCT
bptjm-66	208	1	ultimately	ultimately	ADV
bptjm-66	208	2	,	,	PUNCT
bptjm-66	208	3	many	many	ADJ
bptjm-66	208	4	challenges	challenge	NOUN
bptjm-66	208	5	were	be	AUX
bptjm-66	208	6	found	find	VERB
bptjm-66	208	7	to	to	PART
bptjm-66	208	8	be	be	AUX
bptjm-66	208	9	associated	associate	VERB
bptjm-66	208	10	with	with	ADP
bptjm-66	208	11	this	this	DET
bptjm-66	208	12	treatment	treatment	NOUN
bptjm-66	208	13	modality	modality	NOUN
bptjm-66	208	14	.	.	PUNCT
bptjm-66	209	1	leakage	leakage	NOUN
bptjm-66	209	2	,	,	PUNCT
bptjm-66	209	3	uncontrollable	uncontrollable	ADJ
bptjm-66	209	4	drug	drug	NOUN
bptjm-66	209	5	release	release	NOUN
bptjm-66	209	6	,	,	PUNCT
bptjm-66	209	7	instability	instability	NOUN
bptjm-66	209	8	in	in	ADP
bptjm-66	209	9	storage	storage	NOUN
bptjm-66	209	10	,	,	PUNCT
bptjm-66	209	11	and	and	CCONJ
bptjm-66	209	12	difficulty	difficulty	NOUN
bptjm-66	209	13	in	in	ADP
bptjm-66	209	14	drug	drug	NOUN
bptjm-66	209	15	loading	loading	NOUN
bptjm-66	209	16	limited	limit	VERB
bptjm-66	209	17	the	the	DET
bptjm-66	209	18	use	use	NOUN
bptjm-66	209	19	of	of	ADP
bptjm-66	209	20	liposomes	liposome	NOUN
bptjm-66	209	21	in	in	ADP
bptjm-66	209	22	cancer	cancer	NOUN
bptjm-66	209	23	therapy	therapy	NOUN
bptjm-66	209	24	.	.	PUNCT
bptjm-66	210	1	however	however	ADV
bptjm-66	210	2	,	,	PUNCT
bptjm-66	210	3	they	they	PRON
bptjm-66	210	4	did	do	AUX
bptjm-66	210	5	demonstrate	demonstrate	VERB
bptjm-66	210	6	high	high	ADJ
bptjm-66	210	7	loading	loading	NOUN
bptjm-66	210	8	capacity	capacity	NOUN
bptjm-66	210	9	for	for	ADP
bptjm-66	210	10	hydrophobic	hydrophobic	NOUN
bptjm-66	210	11	substances	substance	NOUN
bptjm-66	210	12	.	.	PUNCT
bptjm-66	211	1	ultimately	ultimately	ADV
bptjm-66	211	2	,	,	PUNCT
bptjm-66	211	3	liposomes	liposome	NOUN
bptjm-66	211	4	are	be	AUX
bptjm-66	211	5	still	still	ADV
bptjm-66	211	6	an	an	DET
bptjm-66	211	7	active	active	ADJ
bptjm-66	211	8	area	area	NOUN
bptjm-66	211	9	of	of	ADP
bptjm-66	211	10	research	research	NOUN
bptjm-66	211	11	for	for	ADP
bptjm-66	211	12	scientists	scientist	NOUN
bptjm-66	211	13	and	and	CCONJ
bptjm-66	211	14	possess	possess	VERB
bptjm-66	211	15	many	many	ADJ
bptjm-66	211	16	challenges	challenge	NOUN
bptjm-66	211	17	that	that	PRON
bptjm-66	211	18	must	must	AUX
bptjm-66	211	19	be	be	AUX
bptjm-66	211	20	overcome	overcome	VERB
bptjm-66	211	21	.	.	PUNCT
bptjm-66	212	1	3.6	3.6	NUM
bptjm-66	212	2	solid	solid	ADJ
bptjm-66	212	3	lipid	lipid	NOUN
bptjm-66	212	4	carriers	carrier	NOUN
bptjm-66	212	5	and	and	CCONJ
bptjm-66	212	6	nanostructured	nanostructure	VERB
bptjm-66	212	7	lipid	lipid	NOUN
bptjm-66	212	8	carriers	carrier	NOUN
bptjm-66	212	9	solid	solid	ADJ
bptjm-66	212	10	lipid	lipid	NOUN
bptjm-66	212	11	nanocarriers	nanocarrier	NOUN
bptjm-66	212	12	have	have	AUX
bptjm-66	212	13	been	be	AUX
bptjm-66	212	14	around	around	ADV
bptjm-66	212	15	for	for	ADP
bptjm-66	212	16	decades	decade	NOUN
bptjm-66	212	17	and	and	CCONJ
bptjm-66	212	18	have	have	AUX
bptjm-66	212	19	been	be	AUX
bptjm-66	212	20	extensively	extensively	ADV
bptjm-66	212	21	researched	research	VERB
bptjm-66	212	22	.	.	PUNCT
bptjm-66	213	1	many	many	ADJ
bptjm-66	213	2	versions	version	NOUN
bptjm-66	213	3	of	of	ADP
bptjm-66	213	4	this	this	DET
bptjm-66	213	5	nanoparticle	nanoparticle	NOUN
bptjm-66	213	6	have	have	AUX
bptjm-66	213	7	been	be	AUX
bptjm-66	213	8	produced	produce	VERB
bptjm-66	213	9	.	.	PUNCT
bptjm-66	214	1	a	a	DET
bptjm-66	214	2	solid	solid	ADJ
bptjm-66	214	3	lipid	lipid	NOUN
bptjm-66	214	4	nanocarrier	nanocarrier	NOUN
bptjm-66	214	5	,	,	PUNCT
bptjm-66	214	6	at	at	ADP
bptjm-66	214	7	its	its	PRON
bptjm-66	214	8	core	core	NOUN
bptjm-66	214	9	,	,	PUNCT
bptjm-66	214	10	is	be	AUX
bptjm-66	214	11	a	a	DET
bptjm-66	214	12	solid	solid	ADJ
bptjm-66	214	13	lipid	lipid	NOUN
bptjm-66	214	14	(	(	PUNCT
bptjm-66	214	15	lipid	lipid	NOUN
bptjm-66	214	16	that	that	PRON
bptjm-66	214	17	is	be	AUX
bptjm-66	214	18	solid	solid	ADJ
bptjm-66	214	19	at	at	ADP
bptjm-66	214	20	room	room	NOUN
bptjm-66	214	21	temperature	temperature	NOUN
bptjm-66	214	22	)	)	PUNCT
bptjm-66	214	23	that	that	PRON
bptjm-66	214	24	is	be	AUX
bptjm-66	214	25	commonly	commonly	ADV
bptjm-66	214	26	composed	compose	VERB
bptjm-66	214	27	of	of	ADP
bptjm-66	214	28	triglycerides	triglyceride	NOUN
bptjm-66	214	29	,	,	PUNCT
bptjm-66	214	30	fatty	fatty	NOUN
bptjm-66	214	31	acids	acid	NOUN
bptjm-66	214	32	,	,	PUNCT
bptjm-66	214	33	waxes	wax	NOUN
bptjm-66	214	34	,	,	PUNCT
bptjm-66	214	35	and	and	CCONJ
bptjm-66	214	36	phospholipids35	phospholipids35	NOUN
bptjm-66	214	37	.	.	PUNCT
bptjm-66	215	1	these	these	DET
bptjm-66	215	2	lipids	lipid	NOUN
bptjm-66	215	3	form	form	VERB
bptjm-66	215	4	a	a	DET
bptjm-66	215	5	matrix	matrix	NOUN
bptjm-66	215	6	of	of	ADP
bptjm-66	215	7	crystalline	crystalline	ADJ
bptjm-66	215	8	structure	structure	NOUN
bptjm-66	215	9	that	that	PRON
bptjm-66	215	10	encapsulates	encapsulate	VERB
bptjm-66	215	11	the	the	DET
bptjm-66	215	12	drug	drug	NOUN
bptjm-66	215	13	to	to	PART
bptjm-66	215	14	be	be	AUX
bptjm-66	215	15	delivered	deliver	VERB
bptjm-66	215	16	.	.	PUNCT
bptjm-66	216	1	surrounding	surround	VERB
bptjm-66	216	2	this	this	DET
bptjm-66	216	3	solid	solid	ADJ
bptjm-66	216	4	lipid	lipid	NOUN
bptjm-66	216	5	nanocarrier	nanocarrier	PROPN
bptjm-66	216	6	core	core	NOUN
bptjm-66	216	7	exists	exist	VERB
bptjm-66	216	8	a	a	DET
bptjm-66	216	9	surfactant	surfactant	ADJ
bptjm-66	216	10	layer	layer	NOUN
bptjm-66	216	11	.	.	PUNCT
bptjm-66	217	1	in	in	ADP
bptjm-66	217	2	chemistry	chemistry	NOUN
bptjm-66	217	3	,	,	PUNCT
bptjm-66	217	4	surfactants	surfactant	NOUN
bptjm-66	217	5	decrease	decrease	VERB
bptjm-66	217	6	the	the	DET
bptjm-66	217	7	surface	surface	NOUN
bptjm-66	217	8	tension	tension	NOUN
bptjm-66	217	9	between	between	ADP
bptjm-66	217	10	adjacent	adjacent	ADJ
bptjm-66	217	11	surfaces	surface	NOUN
bptjm-66	217	12	and	and	CCONJ
bptjm-66	217	13	are	be	AUX
bptjm-66	217	14	amphiphiles	amphiphile	NOUN
bptjm-66	217	15	.	.	PUNCT
bptjm-66	218	1	the	the	DET
bptjm-66	218	2	hydrophilic	hydrophilic	ADJ
bptjm-66	218	3	portion	portion	NOUN
bptjm-66	218	4	of	of	ADP
bptjm-66	218	5	the	the	DET
bptjm-66	218	6	surfactant	surfactant	NOUN
bptjm-66	218	7	faces	face	VERB
bptjm-66	218	8	outward	outward	ADV
bptjm-66	218	9	toward	toward	ADP
bptjm-66	218	10	the	the	DET
bptjm-66	218	11	aqueous	aqueous	ADJ
bptjm-66	218	12	environment	environment	NOUN
bptjm-66	218	13	,	,	PUNCT
bptjm-66	218	14	while	while	SCONJ
bptjm-66	218	15	the	the	DET
bptjm-66	218	16	lipophilic	lipophilic	ADJ
bptjm-66	218	17	portion	portion	NOUN
bptjm-66	218	18	interacts	interact	VERB
bptjm-66	218	19	with	with	ADP
bptjm-66	218	20	the	the	DET
bptjm-66	218	21	lipid	lipid	NOUN
bptjm-66	218	22	core	core	NOUN
bptjm-66	218	23	,	,	PUNCT
bptjm-66	218	24	which	which	PRON
bptjm-66	218	25	acts	act	VERB
bptjm-66	218	26	as	as	ADP
bptjm-66	218	27	a	a	DET
bptjm-66	218	28	stabilizer	stabilizer	NOUN
bptjm-66	218	29	for	for	ADP
bptjm-66	218	30	the	the	DET
bptjm-66	218	31	solid	solid	ADJ
bptjm-66	218	32	lipid	lipid	NOUN
bptjm-66	218	33	core	core	NOUN
bptjm-66	218	34	,	,	PUNCT
bptjm-66	218	35	preventing	prevent	VERB
bptjm-66	218	36	aggregation	aggregation	NOUN
bptjm-66	218	37	or	or	CCONJ
bptjm-66	218	38	coalescence	coalescence	NOUN
bptjm-66	218	39	.	.	PUNCT
bptjm-66	219	1	the	the	DET
bptjm-66	219	2	first	first	ADJ
bptjm-66	219	3	generation	generation	NOUN
bptjm-66	219	4	of	of	ADP
bptjm-66	219	5	this	this	DET
bptjm-66	219	6	nanocarrier	nanocarrier	NOUN
bptjm-66	219	7	was	be	AUX
bptjm-66	219	8	used	use	VERB
bptjm-66	219	9	as	as	ADP
bptjm-66	219	10	a	a	DET
bptjm-66	219	11	vesicle	vesicle	NOUN
bptjm-66	219	12	to	to	PART
bptjm-66	219	13	deliver	deliver	VERB
bptjm-66	219	14	topical	topical	ADJ
bptjm-66	219	15	anti	anti	ADJ
bptjm-66	219	16	-	-	ADJ
bptjm-66	219	17	inflammatory	inflammatory	ADJ
bptjm-66	219	18	drugs	drug	NOUN
bptjm-66	219	19	.	.	PUNCT
bptjm-66	220	1	great	great	ADJ
bptjm-66	220	2	success	success	NOUN
bptjm-66	220	3	was	be	AUX
bptjm-66	220	4	found	find	VERB
bptjm-66	220	5	in	in	ADP
bptjm-66	220	6	the	the	DET
bptjm-66	220	7	controlled	control	VERB
bptjm-66	220	8	release	release	NOUN
bptjm-66	220	9	of	of	ADP
bptjm-66	220	10	the	the	DET
bptjm-66	220	11	drug	drug	NOUN
bptjm-66	220	12	,	,	PUNCT
bptjm-66	220	13	allowing	allow	VERB
bptjm-66	220	14	for	for	ADP
bptjm-66	220	15	berkeley	berkeley	PROPN
bptjm-66	220	16	pharma	pharma	PROPN
bptjm-66	220	17	tech	tech	NOUN
bptjm-66	220	18	journal	journal	NOUN
bptjm-66	220	19	of	of	ADP
bptjm-66	220	20	medicine	medicine	NOUN
bptjm-66	220	21	|	|	ADV
bptjm-66	220	22	14	14	NUM
bptjm-66	220	23	bioaccumulation	bioaccumulation	NOUN
bptjm-66	220	24	in	in	ADP
bptjm-66	220	25	the	the	DET
bptjm-66	220	26	stratum	stratum	NOUN
bptjm-66	220	27	corneum	corneum	NOUN
bptjm-66	220	28	,	,	PUNCT
bptjm-66	220	29	the	the	DET
bptjm-66	220	30	outermost	outermost	ADJ
bptjm-66	220	31	layer	layer	NOUN
bptjm-66	220	32	in	in	ADP
bptjm-66	220	33	the	the	DET
bptjm-66	220	34	epidermis	epidermis	NOUN
bptjm-66	220	35	.	.	PUNCT
bptjm-66	221	1	it	it	PRON
bptjm-66	221	2	has	have	AUX
bptjm-66	221	3	also	also	ADV
bptjm-66	221	4	served	serve	VERB
bptjm-66	221	5	as	as	ADP
bptjm-66	221	6	an	an	DET
bptjm-66	221	7	effective	effective	ADJ
bptjm-66	221	8	nanocarrier	nanocarrier	NOUN
bptjm-66	221	9	for	for	ADP
bptjm-66	221	10	various	various	ADJ
bptjm-66	221	11	pain	pain	NOUN
bptjm-66	221	12	drugs	drug	NOUN
bptjm-66	221	13	.	.	PUNCT
bptjm-66	222	1	epalrestat36	epalrestat36	PROPN
bptjm-66	222	2	,	,	PUNCT
bptjm-66	222	3	a	a	DET
bptjm-66	222	4	treatment	treatment	NOUN
bptjm-66	222	5	for	for	ADP
bptjm-66	222	6	streptozotocin	streptozotocin	NOUN
bptjm-66	222	7	-	-	PUNCT
bptjm-66	222	8	induced	induce	VERB
bptjm-66	222	9	diabetic	diabetic	ADJ
bptjm-66	222	10	neuropathic	neuropathic	ADJ
bptjm-66	222	11	pain	pain	NOUN
bptjm-66	222	12	,	,	PUNCT
bptjm-66	222	13	was	be	AUX
bptjm-66	222	14	delivered	deliver	VERB
bptjm-66	222	15	with	with	ADP
bptjm-66	222	16	solid	solid	ADJ
bptjm-66	222	17	lipid	lipid	NOUN
bptjm-66	222	18	nanocarriers	nanocarrier	NOUN
bptjm-66	222	19	,	,	PUNCT
bptjm-66	222	20	and	and	CCONJ
bptjm-66	222	21	the	the	DET
bptjm-66	222	22	effect	effect	NOUN
bptjm-66	222	23	was	be	AUX
bptjm-66	222	24	measured	measure	VERB
bptjm-66	222	25	in	in	ADP
bptjm-66	222	26	a	a	DET
bptjm-66	222	27	rat	rat	NOUN
bptjm-66	222	28	-	-	PUNCT
bptjm-66	222	29	modeled	model	VERB
bptjm-66	222	30	study	study	NOUN
bptjm-66	222	31	.	.	PUNCT
bptjm-66	223	1	the	the	DET
bptjm-66	223	2	study	study	NOUN
bptjm-66	223	3	tested	test	VERB
bptjm-66	223	4	the	the	DET
bptjm-66	223	5	efficacy	efficacy	NOUN
bptjm-66	223	6	of	of	ADP
bptjm-66	223	7	epalrestat	epalrestat	NOUN
bptjm-66	223	8	encapsulated	encapsulate	VERB
bptjm-66	223	9	nanoparticles	nanoparticle	NOUN
bptjm-66	223	10	at	at	ADP
bptjm-66	223	11	varying	vary	VERB
bptjm-66	223	12	concentrations	concentration	NOUN
bptjm-66	223	13	(	(	PUNCT
bptjm-66	223	14	0.25	0.25	NUM
bptjm-66	223	15	,	,	PUNCT
bptjm-66	223	16	0.50	0.50	NUM
bptjm-66	223	17	,	,	PUNCT
bptjm-66	223	18	1	1	NUM
bptjm-66	223	19	,	,	PUNCT
bptjm-66	223	20	and	and	CCONJ
bptjm-66	223	21	5	5	NUM
bptjm-66	223	22	mg	mg	NUM
bptjm-66	223	23	/	/	SYM
bptjm-66	223	24	kg	kg	NOUN
bptjm-66	223	25	)	)	PUNCT
bptjm-66	223	26	on	on	ADP
bptjm-66	223	27	streptozotocin	streptozotocin	NOUN
bptjm-66	223	28	-	-	PUNCT
bptjm-66	223	29	injected	inject	VERB
bptjm-66	223	30	rats	rat	NOUN
bptjm-66	223	31	.	.	PUNCT
bptjm-66	224	1	the	the	DET
bptjm-66	224	2	various	various	ADJ
bptjm-66	224	3	parameters	parameter	NOUN
bptjm-66	224	4	linked	link	VERB
bptjm-66	224	5	with	with	ADP
bptjm-66	224	6	peripheral	peripheral	ADJ
bptjm-66	224	7	neuropathy	neuropathy	ADJ
bptjm-66	224	8	were	be	AUX
bptjm-66	224	9	subsequently	subsequently	ADV
bptjm-66	224	10	measured	measure	VERB
bptjm-66	224	11	.	.	PUNCT
bptjm-66	225	1	the	the	DET
bptjm-66	225	2	results	result	NOUN
bptjm-66	225	3	were	be	AUX
bptjm-66	225	4	promising	promise	VERB
bptjm-66	225	5	.	.	PUNCT
bptjm-66	226	1	solid	solid	ADJ
bptjm-66	226	2	lipid	lipid	ADJ
bptjm-66	226	3	nanoparticles	nanoparticle	NOUN
bptjm-66	226	4	demonstrated	demonstrate	VERB
bptjm-66	226	5	a	a	DET
bptjm-66	226	6	large	large	ADJ
bptjm-66	226	7	encapsulation	encapsulation	NOUN
bptjm-66	226	8	efficacy	efficacy	NOUN
bptjm-66	226	9	at	at	ADP
bptjm-66	226	10	88	88	NUM
bptjm-66	226	11	±	±	NUM
bptjm-66	226	12	2	2	NUM
bptjm-66	226	13	%	%	NOUN
bptjm-66	226	14	.	.	PUNCT
bptjm-66	227	1	analyzing	analyze	VERB
bptjm-66	227	2	the	the	DET
bptjm-66	227	3	results	result	NOUN
bptjm-66	227	4	,	,	PUNCT
bptjm-66	227	5	the	the	DET
bptjm-66	227	6	tail	tail	NOUN
bptjm-66	227	7	-	-	PUNCT
bptjm-66	227	8	flick	flick	NOUN
bptjm-66	227	9	latency	latency	NOUN
bptjm-66	227	10	time	time	NOUN
bptjm-66	227	11	and	and	CCONJ
bptjm-66	227	12	hot	hot	ADJ
bptjm-66	227	13	plate	plate	NOUN
bptjm-66	227	14	response	response	NOUN
bptjm-66	227	15	time	time	NOUN
bptjm-66	227	16	,	,	PUNCT
bptjm-66	227	17	improved	improve	VERB
bptjm-66	227	18	linearly	linearly	ADV
bptjm-66	227	19	with	with	ADP
bptjm-66	227	20	greater	great	ADJ
bptjm-66	227	21	doses	dose	NOUN
bptjm-66	227	22	of	of	ADP
bptjm-66	227	23	solid	solid	ADJ
bptjm-66	227	24	lipid	lipid	NOUN
bptjm-66	227	25	nanoparticles	nanoparticle	NOUN
bptjm-66	227	26	.	.	PUNCT
bptjm-66	228	1	figure	figure	NOUN
bptjm-66	228	2	2	2	NUM
bptjm-66	228	3	.	.	PUNCT
bptjm-66	229	1	the	the	DET
bptjm-66	229	2	formation	formation	NOUN
bptjm-66	229	3	of	of	ADP
bptjm-66	229	4	solid	solid	ADJ
bptjm-66	229	5	lipid	lipid	NOUN
bptjm-66	229	6	nanocarriers	nanocarrier	NOUN
bptjm-66	229	7	.	.	PUNCT
bptjm-66	230	1	the	the	DET
bptjm-66	230	2	second	second	ADJ
bptjm-66	230	3	generation	generation	NOUN
bptjm-66	230	4	of	of	ADP
bptjm-66	230	5	this	this	DET
bptjm-66	230	6	nanocarrier	nanocarrier	NOUN
bptjm-66	230	7	saw	see	VERB
bptjm-66	230	8	the	the	DET
bptjm-66	230	9	advent	advent	NOUN
bptjm-66	230	10	of	of	ADP
bptjm-66	230	11	nanostructured	nanostructure	VERB
bptjm-66	230	12	lipid	lipid	NOUN
bptjm-66	230	13	carriers	carrier	NOUN
bptjm-66	230	14	(	(	PUNCT
bptjm-66	230	15	nlcs	nlcs	PROPN
bptjm-66	230	16	)	)	PUNCT
bptjm-66	230	17	.	.	PUNCT
bptjm-66	231	1	the	the	DET
bptjm-66	231	2	main	main	ADJ
bptjm-66	231	3	differentiating	differentiate	VERB
bptjm-66	231	4	factor	factor	NOUN
bptjm-66	231	5	between	between	ADP
bptjm-66	231	6	these	these	DET
bptjm-66	231	7	nanocarriers	nanocarrier	NOUN
bptjm-66	231	8	and	and	CCONJ
bptjm-66	231	9	solid	solid	ADJ
bptjm-66	231	10	lipid	lipid	NOUN
bptjm-66	231	11	nanocarriers	nanocarrier	NOUN
bptjm-66	231	12	lies	lie	VERB
bptjm-66	231	13	in	in	ADP
bptjm-66	231	14	the	the	DET
bptjm-66	231	15	liquidized	liquidized	ADJ
bptjm-66	231	16	lipid	lipid	NOUN
bptjm-66	231	17	core37	core37	NOUN
bptjm-66	231	18	.	.	PUNCT
bptjm-66	232	1	the	the	DET
bptjm-66	232	2	oils	oil	NOUN
bptjm-66	232	3	in	in	ADP
bptjm-66	232	4	the	the	DET
bptjm-66	232	5	core	core	NOUN
bptjm-66	232	6	function	function	NOUN
bptjm-66	232	7	by	by	ADP
bptjm-66	232	8	decreasing	decrease	VERB
bptjm-66	232	9	the	the	DET
bptjm-66	232	10	crystallinity	crystallinity	NOUN
bptjm-66	232	11	of	of	ADP
bptjm-66	232	12	the	the	DET
bptjm-66	232	13	lipid	lipid	NOUN
bptjm-66	232	14	core	core	NOUN
bptjm-66	232	15	,	,	PUNCT
bptjm-66	232	16	preventing	prevent	VERB
bptjm-66	232	17	drug	drug	NOUN
bptjm-66	232	18	expulsion	expulsion	NOUN
bptjm-66	232	19	from	from	ADP
bptjm-66	232	20	the	the	DET
bptjm-66	232	21	matrix	matrix	NOUN
bptjm-66	232	22	,	,	PUNCT
bptjm-66	232	23	enhancing	enhance	VERB
bptjm-66	232	24	drug	drug	NOUN
bptjm-66	232	25	loading	loading	NOUN
bptjm-66	232	26	capacity	capacity	NOUN
bptjm-66	232	27	,	,	PUNCT
bptjm-66	232	28	and	and	CCONJ
bptjm-66	232	29	stability	stability	NOUN
bptjm-66	232	30	,	,	PUNCT
bptjm-66	232	31	and	and	CCONJ
bptjm-66	232	32	ensuring	ensure	VERB
bptjm-66	232	33	long	long	ADJ
bptjm-66	232	34	-	-	PUNCT
bptjm-66	232	35	term	term	NOUN
bptjm-66	232	36	physical	physical	ADJ
bptjm-66	232	37	and	and	CCONJ
bptjm-66	232	38	chemical	chemical	NOUN
bptjm-66	232	39	stability	stability	NOUN
bptjm-66	232	40	.	.	PUNCT
bptjm-66	233	1	as	as	ADP
bptjm-66	233	2	a	a	DET
bptjm-66	233	3	result	result	NOUN
bptjm-66	233	4	,	,	PUNCT
bptjm-66	233	5	its	its	PRON
bptjm-66	233	6	loading	loading	NOUN
bptjm-66	233	7	capacity	capacity	NOUN
bptjm-66	233	8	saw	see	VERB
bptjm-66	233	9	an	an	DET
bptjm-66	233	10	increase	increase	NOUN
bptjm-66	233	11	,	,	PUNCT
bptjm-66	233	12	and	and	CCONJ
bptjm-66	233	13	its	its	PRON
bptjm-66	233	14	encapsulation	encapsulation	NOUN
bptjm-66	233	15	rate	rate	NOUN
bptjm-66	233	16	rose	rise	VERB
bptjm-66	233	17	to	to	ADP
bptjm-66	233	18	99.5	99.5	NUM
bptjm-66	233	19	%	%	NOUN
bptjm-66	233	20	.	.	PUNCT
bptjm-66	234	1	now	now	ADV
bptjm-66	234	2	solving	solve	VERB
bptjm-66	234	3	many	many	ADJ
bptjm-66	234	4	of	of	ADP
bptjm-66	234	5	the	the	DET
bptjm-66	234	6	problems	problem	NOUN
bptjm-66	234	7	that	that	PRON
bptjm-66	234	8	plagued	plague	VERB
bptjm-66	234	9	the	the	DET
bptjm-66	234	10	solid	solid	ADJ
bptjm-66	234	11	lipid	lipid	NOUN
bptjm-66	234	12	nanocarrier	nanocarrier	NOUN
bptjm-66	234	13	,	,	PUNCT
bptjm-66	234	14	one	one	NUM
bptjm-66	234	15	of	of	ADP
bptjm-66	234	16	its	its	PRON
bptjm-66	234	17	applications	application	NOUN
bptjm-66	234	18	was	be	AUX
bptjm-66	234	19	the	the	DET
bptjm-66	234	20	delivery	delivery	NOUN
bptjm-66	234	21	enhancement	enhancement	NOUN
bptjm-66	234	22	of	of	ADP
bptjm-66	234	23	topical	topical	ADJ
bptjm-66	234	24	therapeutic	therapeutic	ADJ
bptjm-66	234	25	agents	agent	NOUN
bptjm-66	234	26	like	like	ADP
bptjm-66	234	27	butyl	butyl	NOUN
bptjm-66	234	28	-	-	PUNCT
bptjm-66	234	29	substituted	substitute	VERB
bptjm-66	234	30	benzocaine	benzocaine	NOUN
bptjm-66	234	31	analog	analog	NOUN
bptjm-66	234	32	butamben	butamben	NOUN
bptjm-66	234	33	,	,	PUNCT
bptjm-66	234	34	a	a	DET
bptjm-66	234	35	local	local	ADJ
bptjm-66	234	36	anesthetic	anesthetic	NOUN
bptjm-66	234	37	.	.	PUNCT
bptjm-66	235	1	it	it	PRON
bptjm-66	235	2	proved	prove	VERB
bptjm-66	235	3	to	to	PART
bptjm-66	235	4	decrease	decrease	VERB
bptjm-66	235	5	berkeley	berkeley	PROPN
bptjm-66	235	6	pharma	pharma	PROPN
bptjm-66	235	7	tech	tech	NOUN
bptjm-66	235	8	journal	journal	NOUN
bptjm-66	235	9	of	of	ADP
bptjm-66	235	10	medicine	medicine	NOUN
bptjm-66	235	11	|	|	ADV
bptjm-66	235	12	15	15	NUM
bptjm-66	235	13	toxicity	toxicity	NOUN
bptjm-66	235	14	and	and	CCONJ
bptjm-66	235	15	improve	improve	VERB
bptjm-66	235	16	analgesic	analgesic	ADJ
bptjm-66	235	17	effects	effect	NOUN
bptjm-66	235	18	.	.	PUNCT
bptjm-66	236	1	building	build	VERB
bptjm-66	236	2	off	off	ADP
bptjm-66	236	3	of	of	ADP
bptjm-66	236	4	all	all	DET
bptjm-66	236	5	the	the	DET
bptjm-66	236	6	applications	application	NOUN
bptjm-66	236	7	of	of	ADP
bptjm-66	236	8	solid	solid	ADJ
bptjm-66	236	9	lipid	lipid	NOUN
bptjm-66	236	10	nanoparticles	nanoparticle	NOUN
bptjm-66	236	11	,	,	PUNCT
bptjm-66	236	12	it	it	PRON
bptjm-66	236	13	has	have	AUX
bptjm-66	236	14	been	be	AUX
bptjm-66	236	15	explored	explore	VERB
bptjm-66	236	16	in	in	ADP
bptjm-66	236	17	the	the	DET
bptjm-66	236	18	delivery	delivery	NOUN
bptjm-66	236	19	of	of	ADP
bptjm-66	236	20	gene	gene	NOUN
bptjm-66	236	21	therapy	therapy	NOUN
bptjm-66	236	22	,	,	PUNCT
bptjm-66	236	23	chemotherapy	chemotherapy	NOUN
bptjm-66	236	24	,	,	PUNCT
bptjm-66	236	25	and	and	CCONJ
bptjm-66	236	26	other	other	ADJ
bptjm-66	236	27	treatments	treatment	NOUN
bptjm-66	236	28	.	.	PUNCT
bptjm-66	237	1	3.7	3.7	NUM
bptjm-66	237	2	hydrogels	hydrogel	NOUN
bptjm-66	237	3	hydrogels	hydrogel	NOUN
bptjm-66	237	4	in	in	ADP
bptjm-66	237	5	their	their	PRON
bptjm-66	237	6	simplest	simple	ADJ
bptjm-66	237	7	form	form	NOUN
bptjm-66	237	8	are	be	AUX
bptjm-66	237	9	networks	network	NOUN
bptjm-66	237	10	of	of	ADP
bptjm-66	237	11	water	water	NOUN
bptjm-66	237	12	-	-	PUNCT
bptjm-66	237	13	absorbing	absorb	VERB
bptjm-66	237	14	polymers	polymer	NOUN
bptjm-66	237	15	.	.	PUNCT
bptjm-66	238	1	some	some	DET
bptjm-66	238	2	commonly	commonly	ADV
bptjm-66	238	3	used	use	VERB
bptjm-66	238	4	polymers	polymer	NOUN
bptjm-66	238	5	include	include	VERB
bptjm-66	238	6	polyethylene	polyethylene	NOUN
bptjm-66	238	7	glycol	glycol	NOUN
bptjm-66	238	8	(	(	PUNCT
bptjm-66	238	9	peg	peg	NOUN
bptjm-66	238	10	)	)	PUNCT
bptjm-66	238	11	,	,	PUNCT
bptjm-66	238	12	poly(acrylic	poly(acrylic	PROPN
bptjm-66	238	13	acid	acid	NOUN
bptjm-66	238	14	)	)	PUNCT
bptjm-66	238	15	(	(	PUNCT
bptjm-66	238	16	paa	paa	PROPN
bptjm-66	238	17	)	)	PUNCT
bptjm-66	238	18	,	,	PUNCT
bptjm-66	238	19	polyvinyl	polyvinyl	NOUN
bptjm-66	238	20	alcohol	alcohol	NOUN
bptjm-66	238	21	(	(	PUNCT
bptjm-66	238	22	pva	pva	NOUN
bptjm-66	238	23	)	)	PUNCT
bptjm-66	238	24	,	,	PUNCT
bptjm-66	238	25	hydroxypropyl	hydroxypropyl	VERB
bptjm-66	238	26	methylcellulose	methylcellulose	NOUN
bptjm-66	238	27	(	(	PUNCT
bptjm-66	238	28	hpmc	hpmc	ADJ
bptjm-66	238	29	)	)	PUNCT
bptjm-66	238	30	,	,	PUNCT
bptjm-66	238	31	alginate	alginate	NOUN
bptjm-66	238	32	,	,	PUNCT
bptjm-66	238	33	collagen	collagen	NOUN
bptjm-66	238	34	,	,	PUNCT
bptjm-66	238	35	and	and	CCONJ
bptjm-66	238	36	chitosan	chitosan	NOUN
bptjm-66	238	37	;	;	PUNCT
bptjm-66	238	38	some	some	PRON
bptjm-66	238	39	of	of	ADP
bptjm-66	238	40	these	these	DET
bptjm-66	238	41	hydrophilic	hydrophilic	ADJ
bptjm-66	238	42	polymers	polymer	NOUN
bptjm-66	238	43	are	be	AUX
bptjm-66	238	44	naturally	naturally	ADV
bptjm-66	238	45	forming	form	VERB
bptjm-66	238	46	polymers	polymer	NOUN
bptjm-66	238	47	.	.	PUNCT
bptjm-66	239	1	in	in	ADP
bptjm-66	239	2	the	the	DET
bptjm-66	239	3	world	world	NOUN
bptjm-66	239	4	of	of	ADP
bptjm-66	239	5	anesthetics	anesthetic	NOUN
bptjm-66	239	6	,	,	PUNCT
bptjm-66	239	7	the	the	DET
bptjm-66	239	8	brief	brief	ADJ
bptjm-66	239	9	lifetime	lifetime	NOUN
bptjm-66	239	10	of	of	ADP
bptjm-66	239	11	the	the	DET
bptjm-66	239	12	anesthetics	anesthetic	NOUN
bptjm-66	239	13	and	and	CCONJ
bptjm-66	239	14	toxicity	toxicity	NOUN
bptjm-66	239	15	has	have	AUX
bptjm-66	239	16	been	be	AUX
bptjm-66	239	17	at	at	ADP
bptjm-66	239	18	the	the	DET
bptjm-66	239	19	center	center	NOUN
bptjm-66	239	20	of	of	ADP
bptjm-66	239	21	focus	focus	NOUN
bptjm-66	239	22	when	when	SCONJ
bptjm-66	239	23	attempting	attempt	VERB
bptjm-66	239	24	to	to	PART
bptjm-66	239	25	engineer	engineer	VERB
bptjm-66	239	26	effective	effective	ADJ
bptjm-66	239	27	therapeutics	therapeutic	NOUN
bptjm-66	239	28	.	.	PUNCT
bptjm-66	240	1	hydrogels	hydrogel	NOUN
bptjm-66	240	2	have	have	AUX
bptjm-66	240	3	demonstrated	demonstrate	VERB
bptjm-66	240	4	great	great	ADJ
bptjm-66	240	5	promise	promise	NOUN
bptjm-66	240	6	in	in	ADP
bptjm-66	240	7	combination	combination	NOUN
bptjm-66	240	8	therapy	therapy	NOUN
bptjm-66	240	9	with	with	ADP
bptjm-66	240	10	traditional	traditional	ADJ
bptjm-66	240	11	anesthetics	anesthetic	NOUN
bptjm-66	240	12	in	in	ADP
bptjm-66	240	13	blocking	block	VERB
bptjm-66	240	14	peripheral	peripheral	ADJ
bptjm-66	240	15	nerve	nerve	NOUN
bptjm-66	240	16	blocks	block	NOUN
bptjm-66	240	17	.	.	PUNCT
bptjm-66	241	1	a	a	DET
bptjm-66	241	2	study38	study38	NOUN
bptjm-66	241	3	tested	test	VERB
bptjm-66	241	4	the	the	DET
bptjm-66	241	5	logistics	logistic	NOUN
bptjm-66	241	6	of	of	ADP
bptjm-66	241	7	polycaprolactone	polycaprolactone	NOUN
bptjm-66	241	8	(	(	PUNCT
bptjm-66	241	9	pcl	pcl	NOUN
bptjm-66	241	10	)	)	PUNCT
bptjm-66	241	11	hydrogels	hydrogel	NOUN
bptjm-66	241	12	in	in	ADP
bptjm-66	241	13	delivering	deliver	VERB
bptjm-66	241	14	topical	topical	ADJ
bptjm-66	241	15	agents	agent	NOUN
bptjm-66	241	16	.	.	PUNCT
bptjm-66	242	1	the	the	DET
bptjm-66	242	2	study	study	NOUN
bptjm-66	242	3	determined	determine	VERB
bptjm-66	242	4	that	that	SCONJ
bptjm-66	242	5	drugs	drug	NOUN
bptjm-66	242	6	enriched	enrich	VERB
bptjm-66	242	7	in	in	ADP
bptjm-66	242	8	a	a	DET
bptjm-66	242	9	pcl	pcl	PROPN
bptjm-66	242	10	core	core	NOUN
bptjm-66	242	11	and	and	CCONJ
bptjm-66	242	12	chitosan	chitosan	ADJ
bptjm-66	242	13	shell	shell	NOUN
bptjm-66	242	14	demonstrated	demonstrate	VERB
bptjm-66	242	15	a	a	DET
bptjm-66	242	16	steady	steady	ADJ
bptjm-66	242	17	release	release	NOUN
bptjm-66	242	18	of	of	ADP
bptjm-66	242	19	drugs	drug	NOUN
bptjm-66	242	20	.	.	PUNCT
bptjm-66	243	1	they	they	PRON
bptjm-66	243	2	also	also	ADV
bptjm-66	243	3	tried	try	VERB
bptjm-66	243	4	determining	determine	VERB
bptjm-66	243	5	the	the	DET
bptjm-66	243	6	optimal	optimal	ADJ
bptjm-66	243	7	ropivacaine	ropivacaine	NOUN
bptjm-66	243	8	(	(	PUNCT
bptjm-66	243	9	rpv	rpv	NOUN
bptjm-66	243	10	)	)	PUNCT
bptjm-66	243	11	and	and	CCONJ
bptjm-66	243	12	dexamethasone	dexamethasone	NOUN
bptjm-66	243	13	(	(	PUNCT
bptjm-66	243	14	dem	dem	ADJ
bptjm-66	243	15	)	)	PUNCT
bptjm-66	243	16	nanoparticle	nanoparticle	NOUN
bptjm-66	243	17	composition	composition	NOUN
bptjm-66	243	18	and	and	CCONJ
bptjm-66	243	19	determined	determine	VERB
bptjm-66	243	20	that	that	SCONJ
bptjm-66	243	21	rpv	rpv	NOUN
bptjm-66	243	22	/	/	SYM
bptjm-66	243	23	dem	dem	ADJ
bptjm-66	243	24	ch	ch	PROPN
bptjm-66	243	25	-	-	PUNCT
bptjm-66	243	26	pcl	pcl	PROPN
bptjm-66	243	27	nps-3	nps-3	PUNCT
bptjm-66	243	28	delivered	deliver	VERB
bptjm-66	243	29	the	the	DET
bptjm-66	243	30	best	good	ADJ
bptjm-66	243	31	effects	effect	NOUN
bptjm-66	243	32	,	,	PUNCT
bptjm-66	243	33	the	the	DET
bptjm-66	243	34	mix	mix	NOUN
bptjm-66	243	35	with	with	ADP
bptjm-66	243	36	the	the	DET
bptjm-66	243	37	largest	large	ADJ
bptjm-66	243	38	nanoparticle	nanoparticle	NOUN
bptjm-66	243	39	size	size	NOUN
bptjm-66	243	40	.	.	PUNCT
bptjm-66	244	1	hydrogels	hydrogel	NOUN
bptjm-66	244	2	have	have	AUX
bptjm-66	244	3	also	also	ADV
bptjm-66	244	4	been	be	AUX
bptjm-66	244	5	extensively	extensively	ADV
bptjm-66	244	6	researched	research	VERB
bptjm-66	244	7	in	in	ADP
bptjm-66	244	8	the	the	DET
bptjm-66	244	9	field	field	NOUN
bptjm-66	244	10	of	of	ADP
bptjm-66	244	11	oncology	oncology	NOUN
bptjm-66	244	12	,	,	PUNCT
bptjm-66	244	13	as	as	ADP
bptjm-66	244	14	a	a	DET
bptjm-66	244	15	result	result	NOUN
bptjm-66	244	16	of	of	ADP
bptjm-66	244	17	their	their	PRON
bptjm-66	244	18	impressive	impressive	ADJ
bptjm-66	244	19	biodegradability	biodegradability	NOUN
bptjm-66	244	20	and	and	CCONJ
bptjm-66	244	21	biocompatibility39	biocompatibility39	NOUN
bptjm-66	244	22	.	.	PUNCT
bptjm-66	245	1	specifically	specifically	ADV
bptjm-66	245	2	,	,	PUNCT
bptjm-66	245	3	it	it	PRON
bptjm-66	245	4	has	have	AUX
bptjm-66	245	5	shown	show	VERB
bptjm-66	245	6	great	great	ADJ
bptjm-66	245	7	promise	promise	NOUN
bptjm-66	245	8	in	in	ADP
bptjm-66	245	9	the	the	DET
bptjm-66	245	10	field	field	NOUN
bptjm-66	245	11	of	of	ADP
bptjm-66	245	12	immunotherapy	immunotherapy	NOUN
bptjm-66	245	13	.	.	PUNCT
bptjm-66	246	1	with	with	ADP
bptjm-66	246	2	difficulties	difficulty	NOUN
bptjm-66	246	3	arising	arise	VERB
bptjm-66	246	4	in	in	ADP
bptjm-66	246	5	the	the	DET
bptjm-66	246	6	delivery	delivery	NOUN
bptjm-66	246	7	of	of	ADP
bptjm-66	246	8	monoclonal	monoclonal	NOUN
bptjm-66	246	9	antibodies	antibody	NOUN
bptjm-66	246	10	(	(	PUNCT
bptjm-66	246	11	immune	immune	ADJ
bptjm-66	246	12	checkpoint	checkpoint	NOUN
bptjm-66	246	13	inhibitors	inhibitor	NOUN
bptjm-66	246	14	)	)	PUNCT
bptjm-66	246	15	,	,	PUNCT
bptjm-66	246	16	hydrogels	hydrogel	NOUN
bptjm-66	246	17	serve	serve	VERB
bptjm-66	246	18	as	as	ADP
bptjm-66	246	19	the	the	DET
bptjm-66	246	20	perfect	perfect	ADJ
bptjm-66	246	21	transport	transport	NOUN
bptjm-66	246	22	vesicle	vesicle	NOUN
bptjm-66	246	23	.	.	PUNCT
bptjm-66	247	1	(	(	PUNCT
bptjm-66	247	2	li	li	PROPN
bptjm-66	247	3	et	et	PROPN
bptjm-66	247	4	al	al	PROPN
bptjm-66	247	5	.	.	PROPN
bptjm-66	247	6	,	,	PUNCT
bptjm-66	247	7	2023)40	2023)40	NUM
bptjm-66	247	8	reported	report	VERB
bptjm-66	247	9	that	that	SCONJ
bptjm-66	247	10	the	the	DET
bptjm-66	247	11	alginate	alginate	NOUN
bptjm-66	247	12	hydrogel	hydrogel	NOUN
bptjm-66	247	13	with	with	ADP
bptjm-66	247	14	protoporphyrin	protoporphyrin	NOUN
bptjm-66	247	15	ix	ix	X
bptjm-66	247	16	(	(	PUNCT
bptjm-66	247	17	ppix)-modified	ppix)-modifie	VERB
bptjm-66	247	18	iron	iron	NOUN
bptjm-66	247	19	oxide	oxide	NOUN
bptjm-66	247	20	(	(	PUNCT
bptjm-66	247	21	fe3o4	fe3o4	NOUN
bptjm-66	247	22	)	)	PUNCT
bptjm-66	247	23	nanoparticles	nanoparticle	NOUN
bptjm-66	247	24	demonstrated	demonstrate	VERB
bptjm-66	247	25	high	high	ADJ
bptjm-66	247	26	control	control	NOUN
bptjm-66	247	27	over	over	ADP
bptjm-66	247	28	the	the	DET
bptjm-66	247	29	performance	performance	NOUN
bptjm-66	247	30	of	of	ADP
bptjm-66	247	31	photodynamic	photodynamic	ADJ
bptjm-66	247	32	and	and	CCONJ
bptjm-66	247	33	chemodynamic	chemodynamic	ADJ
bptjm-66	247	34	therapies41	therapies41	NOUN
bptjm-66	247	35	.	.	PUNCT
bptjm-66	248	1	another	another	DET
bptjm-66	248	2	study	study	NOUN
bptjm-66	248	3	conducted	conduct	VERB
bptjm-66	248	4	by	by	ADP
bptjm-66	248	5	li	li	PROPN
bptjm-66	248	6	et	et	PROPN
bptjm-66	248	7	al	al	PROPN
bptjm-66	248	8	.	.	PROPN
bptjm-66	248	9	,	,	PUNCT
bptjm-66	248	10	2021	2021	NUM
bptjm-66	248	11	)	)	PUNCT
bptjm-66	248	12	demonstrated	demonstrate	VERB
bptjm-66	248	13	how	how	SCONJ
bptjm-66	248	14	a	a	DET
bptjm-66	248	15	hybrid	hybrid	ADJ
bptjm-66	248	16	peptide	peptide	NOUN
bptjm-66	248	17	hydrogel	hydrogel	NOUN
bptjm-66	248	18	of	of	ADP
bptjm-66	248	19	melittin	melittin	PROPN
bptjm-66	248	20	(	(	PUNCT
bptjm-66	248	21	rada-320	rada-320	NOUN
bptjm-66	248	22	,	,	PUNCT
bptjm-66	248	23	titanium	titanium	NOUN
bptjm-66	248	24	,	,	PUNCT
bptjm-66	248	25	and	and	CCONJ
bptjm-66	248	26	doxorubicin	doxorubicin	PROPN
bptjm-66	248	27	(	(	PUNCT
bptjm-66	248	28	dox	dox	NOUN
bptjm-66	248	29	)	)	PUNCT
bptjm-66	248	30	controlled	control	VERB
bptjm-66	248	31	the	the	DET
bptjm-66	248	32	release	release	NOUN
bptjm-66	248	33	of	of	ADP
bptjm-66	248	34	therapeutics	therapeutic	NOUN
bptjm-66	248	35	-	-	PUNCT
bptjm-66	248	36	that	that	DET
bptjm-66	248	37	activated	activate	VERB
bptjm-66	248	38	immune	immune	ADJ
bptjm-66	248	39	cells	cell	NOUN
bptjm-66	248	40	,	,	PUNCT
bptjm-66	248	41	depleting	deplete	VERB
bptjm-66	248	42	the	the	DET
bptjm-66	248	43	m2	m2	PROPN
bptjm-66	248	44	-	-	PUNCT
bptjm-66	248	45	like	like	ADJ
bptjm-66	248	46	tumor	tumor	NOUN
bptjm-66	248	47	-	-	PUNCT
bptjm-66	248	48	associated	associate	VERB
bptjm-66	248	49	macrophages	macrophage	NOUN
bptjm-66	248	50	,	,	PUNCT
bptjm-66	248	51	effectively	effectively	ADV
bptjm-66	248	52	reshaping	reshape	VERB
bptjm-66	248	53	the	the	DET
bptjm-66	248	54	immunosuppressive	immunosuppressive	ADJ
bptjm-66	248	55	tumor	tumor	NOUN
bptjm-66	248	56	microenvironment42	microenvironment42	NOUN
bptjm-66	248	57	.	.	PUNCT
bptjm-66	249	1	altering	alter	VERB
bptjm-66	249	2	the	the	DET
bptjm-66	249	3	berkeley	berkeley	PROPN
bptjm-66	249	4	pharma	pharma	PROPN
bptjm-66	249	5	tech	tech	NOUN
bptjm-66	249	6	journal	journal	NOUN
bptjm-66	249	7	of	of	ADP
bptjm-66	249	8	medicine	medicine	NOUN
bptjm-66	249	9	|	|	ADV
bptjm-66	249	10	16	16	NUM
bptjm-66	249	11	microenvironment	microenvironment	NOUN
bptjm-66	249	12	of	of	ADP
bptjm-66	249	13	melanoma	melanoma	NOUN
bptjm-66	249	14	gives	give	VERB
bptjm-66	249	15	promise	promise	NOUN
bptjm-66	249	16	to	to	ADP
bptjm-66	249	17	the	the	DET
bptjm-66	249	18	capability	capability	NOUN
bptjm-66	249	19	to	to	PART
bptjm-66	249	20	alter	alter	VERB
bptjm-66	249	21	other	other	ADJ
bptjm-66	249	22	tumor	tumor	NOUN
bptjm-66	249	23	microenvironments	microenvironment	NOUN
bptjm-66	249	24	present	present	ADJ
bptjm-66	249	25	in	in	ADP
bptjm-66	249	26	other	other	ADJ
bptjm-66	249	27	cancers	cancer	NOUN
bptjm-66	249	28	.	.	PUNCT
bptjm-66	250	1	figure	figure	VERB
bptjm-66	250	2	3	3	NUM
bptjm-66	250	3	.	.	PUNCT
bptjm-66	250	4	hydrogel	hydrogel	NOUN
bptjm-66	250	5	into	into	ADP
bptjm-66	250	6	a	a	DET
bptjm-66	250	7	cell	cell	NOUN
bptjm-66	250	8	3.8	3.8	NUM
bptjm-66	250	9	micelles	micelle	NOUN
bptjm-66	250	10	in	in	ADP
bptjm-66	250	11	its	its	PRON
bptjm-66	250	12	simplest	simple	ADJ
bptjm-66	250	13	form	form	NOUN
bptjm-66	250	14	,	,	PUNCT
bptjm-66	250	15	micelles	micelle	NOUN
bptjm-66	250	16	are	be	AUX
bptjm-66	250	17	aggregates	aggregate	NOUN
bptjm-66	250	18	of	of	ADP
bptjm-66	250	19	amphiphilic	amphiphilic	ADJ
bptjm-66	250	20	molecules	molecule	NOUN
bptjm-66	250	21	that	that	PRON
bptjm-66	250	22	have	have	AUX
bptjm-66	250	23	self	self	NOUN
bptjm-66	250	24	-	-	PUNCT
bptjm-66	250	25	assembled	assemble	VERB
bptjm-66	250	26	into	into	ADP
bptjm-66	250	27	a	a	DET
bptjm-66	250	28	spherical	spherical	ADJ
bptjm-66	250	29	geometry	geometry	NOUN
bptjm-66	250	30	.	.	PUNCT
bptjm-66	251	1	they	they	PRON
bptjm-66	251	2	are	be	AUX
bptjm-66	251	3	formed	form	VERB
bptjm-66	251	4	by	by	ADP
bptjm-66	251	5	submerging	submerge	VERB
bptjm-66	251	6	common	common	ADJ
bptjm-66	251	7	amphiphiles	amphiphile	NOUN
bptjm-66	251	8	,	,	PUNCT
bptjm-66	251	9	like	like	ADP
bptjm-66	251	10	surfactants	surfactant	NOUN
bptjm-66	251	11	,	,	PUNCT
bptjm-66	251	12	in	in	ADP
bptjm-66	251	13	an	an	DET
bptjm-66	251	14	aqueous	aqueous	ADJ
bptjm-66	251	15	solution	solution	NOUN
bptjm-66	251	16	,	,	PUNCT
bptjm-66	251	17	where	where	SCONJ
bptjm-66	251	18	the	the	DET
bptjm-66	251	19	hydrophilic	hydrophilic	ADJ
bptjm-66	251	20	heads	head	NOUN
bptjm-66	251	21	shield	shield	VERB
bptjm-66	251	22	the	the	DET
bptjm-66	251	23	hydrophobic	hydrophobic	NOUN
bptjm-66	251	24	tails	tail	NOUN
bptjm-66	251	25	from	from	ADP
bptjm-66	251	26	the	the	DET
bptjm-66	251	27	polar	polar	ADJ
bptjm-66	251	28	aqueous	aqueous	ADJ
bptjm-66	251	29	environment	environment	NOUN
bptjm-66	251	30	.	.	PUNCT
bptjm-66	252	1	this	this	DET
bptjm-66	252	2	structure	structure	NOUN
bptjm-66	252	3	mirrors	mirror	VERB
bptjm-66	252	4	that	that	PRON
bptjm-66	252	5	of	of	ADP
bptjm-66	252	6	the	the	DET
bptjm-66	252	7	phospholipid	phospholipid	NOUN
bptjm-66	252	8	bilayer	bilayer	NOUN
bptjm-66	252	9	of	of	ADP
bptjm-66	252	10	cells	cell	NOUN
bptjm-66	252	11	,	,	PUNCT
bptjm-66	252	12	as	as	SCONJ
bptjm-66	252	13	there	there	PRON
bptjm-66	252	14	exists	exist	VERB
bptjm-66	252	15	a	a	DET
bptjm-66	252	16	hydrophilic	hydrophilic	ADJ
bptjm-66	252	17	head	head	NOUN
bptjm-66	252	18	with	with	ADP
bptjm-66	252	19	hydrophobic	hydrophobic	NOUN
bptjm-66	252	20	tails	tail	NOUN
bptjm-66	252	21	.	.	PUNCT
bptjm-66	253	1	when	when	SCONJ
bptjm-66	253	2	applied	apply	VERB
bptjm-66	253	3	to	to	ADP
bptjm-66	253	4	the	the	DET
bptjm-66	253	5	field	field	NOUN
bptjm-66	253	6	of	of	ADP
bptjm-66	253	7	therapeutics	therapeutic	NOUN
bptjm-66	253	8	development	development	NOUN
bptjm-66	253	9	,	,	PUNCT
bptjm-66	253	10	micelles	micelle	NOUN
bptjm-66	253	11	can	can	AUX
bptjm-66	253	12	encapsulate	encapsulate	VERB
bptjm-66	253	13	drugs	drug	NOUN
bptjm-66	253	14	in	in	ADP
bptjm-66	253	15	their	their	PRON
bptjm-66	253	16	inner	inner	ADJ
bptjm-66	253	17	compartment	compartment	NOUN
bptjm-66	253	18	.	.	PUNCT
bptjm-66	254	1	what	what	PRON
bptjm-66	254	2	differentiates	differentiate	VERB
bptjm-66	254	3	micelles	micelle	NOUN
bptjm-66	254	4	from	from	ADP
bptjm-66	254	5	other	other	ADJ
bptjm-66	254	6	nanocarriers	nanocarrier	NOUN
bptjm-66	254	7	is	be	AUX
bptjm-66	254	8	their	their	PRON
bptjm-66	254	9	minute	minute	ADJ
bptjm-66	254	10	size	size	NOUN
bptjm-66	254	11	,	,	PUNCT
bptjm-66	254	12	being	be	AUX
bptjm-66	254	13	sub	sub	NOUN
bptjm-66	254	14	50	50	NUM
bptjm-66	254	15	nanometers	nanometer	NOUN
bptjm-66	254	16	in	in	ADP
bptjm-66	254	17	size	size	NOUN
bptjm-66	254	18	.	.	PUNCT
bptjm-66	255	1	combined	combine	VERB
bptjm-66	255	2	with	with	ADP
bptjm-66	255	3	their	their	PRON
bptjm-66	255	4	cell	cell	NOUN
bptjm-66	255	5	-	-	PUNCT
bptjm-66	255	6	like	like	ADJ
bptjm-66	255	7	coatings	coating	NOUN
bptjm-66	255	8	,	,	PUNCT
bptjm-66	255	9	these	these	DET
bptjm-66	255	10	particles	particle	NOUN
bptjm-66	255	11	have	have	VERB
bptjm-66	255	12	accessibility	accessibility	NOUN
bptjm-66	255	13	to	to	ADP
bptjm-66	255	14	deeper	deep	ADJ
bptjm-66	255	15	tissue	tissue	NOUN
bptjm-66	255	16	locations	location	NOUN
bptjm-66	255	17	,	,	PUNCT
bptjm-66	255	18	increasing	increase	VERB
bptjm-66	255	19	the	the	DET
bptjm-66	255	20	range	range	NOUN
bptjm-66	255	21	of	of	ADP
bptjm-66	255	22	drug	drug	NOUN
bptjm-66	255	23	delivery	delivery	NOUN
bptjm-66	255	24	distance	distance	NOUN
bptjm-66	255	25	.	.	PUNCT
bptjm-66	256	1	micelles	micelle	NOUN
bptjm-66	256	2	are	be	AUX
bptjm-66	256	3	also	also	ADV
bptjm-66	256	4	easily	easily	ADV
bptjm-66	256	5	manufactured	manufacture	VERB
bptjm-66	256	6	,	,	PUNCT
bptjm-66	256	7	increasing	increase	VERB
bptjm-66	256	8	their	their	PRON
bptjm-66	256	9	accessibility	accessibility	NOUN
bptjm-66	256	10	relative	relative	ADJ
bptjm-66	256	11	to	to	ADP
bptjm-66	256	12	the	the	DET
bptjm-66	256	13	previously	previously	ADV
bptjm-66	256	14	discussed	discuss	VERB
bptjm-66	256	15	nanocarriers	nanocarrier	NOUN
bptjm-66	256	16	.	.	PUNCT
bptjm-66	257	1	though	though	SCONJ
bptjm-66	257	2	there	there	PRON
bptjm-66	257	3	are	be	VERB
bptjm-66	257	4	many	many	ADJ
bptjm-66	257	5	benefits	benefit	NOUN
bptjm-66	257	6	to	to	ADP
bptjm-66	257	7	this	this	DET
bptjm-66	257	8	nanocarrier	nanocarrier	NOUN
bptjm-66	257	9	,	,	PUNCT
bptjm-66	257	10	a	a	DET
bptjm-66	257	11	major	major	ADJ
bptjm-66	257	12	drawback	drawback	NOUN
bptjm-66	257	13	includes	include	VERB
bptjm-66	257	14	instability	instability	NOUN
bptjm-66	257	15	in	in	ADP
bptjm-66	257	16	fluctuating	fluctuate	VERB
bptjm-66	257	17	environments	environment	NOUN
bptjm-66	257	18	.	.	PUNCT
bptjm-66	258	1	as	as	ADP
bptjm-66	258	2	a	a	DET
bptjm-66	258	3	result	result	NOUN
bptjm-66	258	4	,	,	PUNCT
bptjm-66	258	5	it	it	PRON
bptjm-66	258	6	may	may	AUX
bptjm-66	258	7	disintegrate	disintegrate	VERB
bptjm-66	258	8	in	in	ADP
bptjm-66	258	9	variable	variable	ADJ
bptjm-66	258	10	environments	environment	NOUN
bptjm-66	258	11	,	,	PUNCT
bptjm-66	258	12	like	like	ADP
bptjm-66	258	13	the	the	DET
bptjm-66	258	14	bloodstream	bloodstream	NOUN
bptjm-66	258	15	,	,	PUNCT
bptjm-66	258	16	thereby	thereby	ADV
bptjm-66	258	17	reducing	reduce	VERB
bptjm-66	258	18	therapeutic	therapeutic	ADJ
bptjm-66	258	19	effectiveness	effectiveness	NOUN
bptjm-66	258	20	of	of	ADP
bptjm-66	258	21	the	the	DET
bptjm-66	258	22	nanocarrier	nanocarrier	NOUN
bptjm-66	258	23	.	.	PUNCT
bptjm-66	259	1	current	current	ADJ
bptjm-66	259	2	research	research	NOUN
bptjm-66	259	3	efforts	effort	NOUN
bptjm-66	259	4	are	be	AUX
bptjm-66	259	5	investigating	investigate	VERB
bptjm-66	259	6	the	the	DET
bptjm-66	259	7	possibility	possibility	NOUN
bptjm-66	259	8	of	of	ADP
bptjm-66	259	9	crosslinking	crosslinke	VERB
bptjm-66	259	10	various	various	ADJ
bptjm-66	259	11	structures	structure	NOUN
bptjm-66	259	12	to	to	PART
bptjm-66	259	13	prevent	prevent	VERB
bptjm-66	259	14	premature	premature	ADJ
bptjm-66	259	15	release	release	NOUN
bptjm-66	259	16	of	of	ADP
bptjm-66	259	17	therapeutic	therapeutic	ADJ
bptjm-66	259	18	agents43	agents43	NOUN
bptjm-66	259	19	.	.	PUNCT
bptjm-66	260	1	like	like	ADP
bptjm-66	260	2	any	any	DET
bptjm-66	260	3	other	other	ADJ
bptjm-66	260	4	nanocarriers	nanocarrier	NOUN
bptjm-66	260	5	,	,	PUNCT
bptjm-66	260	6	micelles	micelle	NOUN
bptjm-66	260	7	are	be	AUX
bptjm-66	260	8	currently	currently	ADV
bptjm-66	260	9	being	be	AUX
bptjm-66	260	10	investigated	investigate	VERB
bptjm-66	260	11	for	for	ADP
bptjm-66	260	12	their	their	PRON
bptjm-66	260	13	role	role	NOUN
bptjm-66	260	14	in	in	ADP
bptjm-66	260	15	delivering	deliver	VERB
bptjm-66	260	16	therapeutic	therapeutic	ADJ
bptjm-66	260	17	agents	agent	NOUN
bptjm-66	260	18	to	to	ADP
bptjm-66	260	19	tumors	tumor	NOUN
bptjm-66	260	20	.	.	PUNCT
bptjm-66	261	1	their	their	PRON
bptjm-66	261	2	small	small	ADJ
bptjm-66	261	3	size	size	NOUN
bptjm-66	261	4	allows	allow	VERB
bptjm-66	261	5	them	they	PRON
bptjm-66	261	6	to	to	PART
bptjm-66	261	7	permeate	permeate	VERB
bptjm-66	261	8	well	well	ADV
bptjm-66	261	9	through	through	ADP
bptjm-66	261	10	certain	certain	ADJ
bptjm-66	261	11	systems	system	NOUN
bptjm-66	261	12	,	,	PUNCT
bptjm-66	261	13	like	like	ADP
bptjm-66	261	14	the	the	DET
bptjm-66	261	15	kidney	kidney	NOUN
bptjm-66	261	16	,	,	PUNCT
bptjm-66	261	17	and	and	CCONJ
bptjm-66	261	18	evade	evade	VERB
bptjm-66	261	19	elimination	elimination	NOUN
bptjm-66	261	20	by	by	ADP
bptjm-66	261	21	the	the	DET
bptjm-66	261	22	liver	liver	NOUN
bptjm-66	261	23	or	or	CCONJ
bptjm-66	261	24	spleen	spleen	NOUN
bptjm-66	261	25	.	.	PUNCT
bptjm-66	262	1	their	their	PRON
bptjm-66	262	2	minute	minute	ADJ
bptjm-66	262	3	size	size	NOUN
bptjm-66	262	4	allows	allow	VERB
bptjm-66	262	5	precise	precise	ADJ
bptjm-66	262	6	localization	localization	NOUN
bptjm-66	262	7	in	in	ADP
bptjm-66	262	8	certain	certain	ADJ
bptjm-66	262	9	tissues	tissue	NOUN
bptjm-66	262	10	,	,	PUNCT
bptjm-66	262	11	improving	improve	VERB
bptjm-66	262	12	therapeutics	therapeutic	NOUN
bptjm-66	262	13	delivery	delivery	NOUN
bptjm-66	262	14	.	.	PUNCT
bptjm-66	263	1	berkeley	berkeley	PROPN
bptjm-66	263	2	pharma	pharma	PROPN
bptjm-66	263	3	tech	tech	PROPN
bptjm-66	263	4	journal	journal	NOUN
bptjm-66	263	5	of	of	ADP
bptjm-66	263	6	medicine	medicine	NOUN
bptjm-66	263	7	|	|	ADV
bptjm-66	263	8	17	17	NUM
bptjm-66	263	9	by	by	ADP
bptjm-66	263	10	modifying	modify	VERB
bptjm-66	263	11	the	the	DET
bptjm-66	263	12	surface	surface	NOUN
bptjm-66	263	13	of	of	ADP
bptjm-66	263	14	micelles	micelle	NOUN
bptjm-66	263	15	with	with	ADP
bptjm-66	263	16	ligands	ligand	NOUN
bptjm-66	263	17	that	that	PRON
bptjm-66	263	18	can	can	AUX
bptjm-66	263	19	specifically	specifically	ADV
bptjm-66	263	20	recognize	recognize	VERB
bptjm-66	263	21	and	and	CCONJ
bptjm-66	263	22	bind	bind	VERB
bptjm-66	263	23	to	to	ADP
bptjm-66	263	24	receptors	receptor	NOUN
bptjm-66	263	25	overexpressed	overexpresse	VERB
bptjm-66	263	26	on	on	ADP
bptjm-66	263	27	the	the	DET
bptjm-66	263	28	tumor	tumor	NOUN
bptjm-66	263	29	cells	cell	NOUN
bptjm-66	263	30	,	,	PUNCT
bptjm-66	263	31	a	a	DET
bptjm-66	263	32	targeting	targeting	NOUN
bptjm-66	263	33	modality	modality	NOUN
bptjm-66	263	34	is	be	AUX
bptjm-66	263	35	established	establish	VERB
bptjm-66	263	36	.	.	PUNCT
bptjm-66	264	1	this	this	PRON
bptjm-66	264	2	is	be	AUX
bptjm-66	264	3	evident	evident	ADJ
bptjm-66	264	4	in	in	ADP
bptjm-66	264	5	approved	approve	VERB
bptjm-66	264	6	polymeric	polymeric	ADJ
bptjm-66	264	7	nano	nano	NOUN
bptjm-66	264	8	micelle	micelle	NOUN
bptjm-66	264	9	-	-	PUNCT
bptjm-66	264	10	based	base	VERB
bptjm-66	264	11	drugs	drug	NOUN
bptjm-66	264	12	on	on	ADP
bptjm-66	264	13	the	the	DET
bptjm-66	264	14	market	market	NOUN
bptjm-66	264	15	for	for	ADP
bptjm-66	264	16	cancer	cancer	NOUN
bptjm-66	264	17	treatment44	treatment44	NOUN
bptjm-66	264	18	.	.	PUNCT
bptjm-66	265	1	figure	figure	VERB
bptjm-66	265	2	4	4	NUM
bptjm-66	265	3	.	.	PUNCT
bptjm-66	266	1	loading	loading	NOUN
bptjm-66	266	2	of	of	ADP
bptjm-66	266	3	a	a	DET
bptjm-66	266	4	micellar	micellar	ADJ
bptjm-66	266	5	nanocarrier	nanocarrier	NOUN
bptjm-66	266	6	genexol	genexol	NOUN
bptjm-66	266	7	-	-	PUNCT
bptjm-66	266	8	pm	pm	NOUN
bptjm-66	266	9	,	,	PUNCT
bptjm-66	266	10	a	a	DET
bptjm-66	266	11	micelle	micelle	NOUN
bptjm-66	266	12	-	-	PUNCT
bptjm-66	266	13	based	base	VERB
bptjm-66	266	14	drug	drug	NOUN
bptjm-66	266	15	,	,	PUNCT
bptjm-66	266	16	has	have	AUX
bptjm-66	266	17	been	be	AUX
bptjm-66	266	18	approved	approve	VERB
bptjm-66	266	19	for	for	ADP
bptjm-66	266	20	the	the	DET
bptjm-66	266	21	treatment	treatment	NOUN
bptjm-66	266	22	of	of	ADP
bptjm-66	266	23	breast	breast	NOUN
bptjm-66	266	24	cancer	cancer	NOUN
bptjm-66	266	25	,	,	PUNCT
bptjm-66	266	26	non	non	ADJ
bptjm-66	266	27	-	-	ADJ
bptjm-66	266	28	small	small	ADJ
bptjm-66	266	29	-	-	PUNCT
bptjm-66	266	30	cell	cell	NOUN
bptjm-66	266	31	lung	lung	NOUN
bptjm-66	266	32	cancer	cancer	NOUN
bptjm-66	266	33	,	,	PUNCT
bptjm-66	266	34	and	and	CCONJ
bptjm-66	266	35	ovarian	ovarian	ADJ
bptjm-66	266	36	cancer	cancer	NOUN
bptjm-66	266	37	.	.	PUNCT
bptjm-66	267	1	it	it	PRON
bptjm-66	267	2	is	be	AUX
bptjm-66	267	3	also	also	ADV
bptjm-66	267	4	undergoing	undergo	VERB
bptjm-66	267	5	clinical	clinical	ADJ
bptjm-66	267	6	trials	trial	NOUN
bptjm-66	267	7	for	for	ADP
bptjm-66	267	8	a	a	DET
bptjm-66	267	9	variety	variety	NOUN
bptjm-66	267	10	of	of	ADP
bptjm-66	267	11	cancers	cancer	NOUN
bptjm-66	267	12	.	.	PUNCT
bptjm-66	268	1	in	in	ADP
bptjm-66	268	2	a	a	DET
bptjm-66	268	3	phase	phase	NOUN
bptjm-66	268	4	ii	ii	NOUN
bptjm-66	268	5	study	study	NOUN
bptjm-66	268	6	of	of	ADP
bptjm-66	268	7	genexol	genexol	NOUN
bptjm-66	268	8	-	-	PUNCT
bptjm-66	268	9	pm	pm	NOUN
bptjm-66	268	10	in	in	ADP
bptjm-66	268	11	patients	patient	NOUN
bptjm-66	268	12	with	with	ADP
bptjm-66	268	13	locally	locally	ADV
bptjm-66	268	14	advanced	advanced	ADJ
bptjm-66	268	15	or	or	CCONJ
bptjm-66	268	16	metastatic	metastatic	ADJ
bptjm-66	268	17	pancreatic	pancreatic	ADJ
bptjm-66	268	18	cancer	cancer	NOUN
bptjm-66	268	19	,	,	PUNCT
bptjm-66	268	20	common	common	ADJ
bptjm-66	268	21	side	side	NOUN
bptjm-66	268	22	effects	effect	NOUN
bptjm-66	268	23	were	be	AUX
bptjm-66	268	24	comparable	comparable	ADJ
bptjm-66	268	25	to	to	ADP
bptjm-66	268	26	those	those	PRON
bptjm-66	268	27	of	of	ADP
bptjm-66	268	28	taxol	taxol	PROPN
bptjm-66	268	29	in	in	ADP
bptjm-66	268	30	a	a	DET
bptjm-66	268	31	dose	dose	NOUN
bptjm-66	268	32	of	of	ADP
bptjm-66	268	33	300	300	NUM
bptjm-66	268	34	mg	mg	NOUN
bptjm-66	268	35	/	/	SYM
bptjm-66	268	36	m2	m2	PROPN
bptjm-66	268	37	every	every	DET
bptjm-66	268	38	three	three	NUM
bptjm-66	268	39	weeks	week	NOUN
bptjm-66	268	40	.	.	PUNCT
bptjm-66	269	1	the	the	DET
bptjm-66	269	2	general	general	ADJ
bptjm-66	269	3	reaction	reaction	NOUN
bptjm-66	269	4	rate	rate	NOUN
bptjm-66	269	5	was	be	AUX
bptjm-66	269	6	6.7	6.7	NUM
bptjm-66	269	7	%	%	NOUN
bptjm-66	269	8	,	,	PUNCT
bptjm-66	269	9	with	with	ADP
bptjm-66	269	10	1	1	NUM
bptjm-66	269	11	patient	patient	NOUN
bptjm-66	269	12	in	in	ADP
bptjm-66	269	13	complete	complete	ADJ
bptjm-66	269	14	reaction	reaction	NOUN
bptjm-66	269	15	and	and	CCONJ
bptjm-66	269	16	2	2	NUM
bptjm-66	269	17	patients	patient	NOUN
bptjm-66	269	18	in	in	ADP
bptjm-66	269	19	halfway	halfway	NOUN
bptjm-66	269	20	reactions	reaction	NOUN
bptjm-66	269	21	,	,	PUNCT
bptjm-66	269	22	and	and	CCONJ
bptjm-66	269	23	the	the	DET
bptjm-66	269	24	infectious	infectious	ADJ
bptjm-66	269	25	prevention	prevention	NOUN
bptjm-66	269	26	rate	rate	NOUN
bptjm-66	269	27	was	be	AUX
bptjm-66	269	28	60	60	NUM
bptjm-66	269	29	%	%	NOUN
bptjm-66	269	30	.	.	PUNCT
bptjm-66	270	1	the	the	DET
bptjm-66	270	2	median	median	PROPN
bptjm-66	270	3	pfs	pfs	PROPN
bptjm-66	270	4	was	be	AUX
bptjm-66	270	5	2.8	2.8	NUM
bptjm-66	270	6	months	month	NOUN
bptjm-66	270	7	,	,	PUNCT
bptjm-66	270	8	and	and	CCONJ
bptjm-66	270	9	the	the	DET
bptjm-66	270	10	median	median	ADJ
bptjm-66	270	11	overall	overall	ADJ
bptjm-66	270	12	survival	survival	NOUN
bptjm-66	270	13	was	be	AUX
bptjm-66	270	14	6.5	6.5	NUM
bptjm-66	270	15	months	month	NOUN
bptjm-66	270	16	.	.	PUNCT
bptjm-66	271	1	neutropenia	neutropenia	NOUN
bptjm-66	271	2	(	(	PUNCT
bptjm-66	271	3	40.0	40.0	NUM
bptjm-66	271	4	%	%	NOUN
bptjm-66	271	5	)	)	PUNCT
bptjm-66	271	6	,	,	PUNCT
bptjm-66	271	7	fatigue	fatigue	NOUN
bptjm-66	271	8	(	(	PUNCT
bptjm-66	271	9	17.8	17.8	NUM
bptjm-66	271	10	%	%	NOUN
bptjm-66	271	11	)	)	PUNCT
bptjm-66	271	12	,	,	PUNCT
bptjm-66	271	13	infection	infection	NOUN
bptjm-66	271	14	(	(	PUNCT
bptjm-66	271	15	13.3	13.3	NUM
bptjm-66	271	16	%	%	NOUN
bptjm-66	271	17	)	)	PUNCT
bptjm-66	271	18	,	,	PUNCT
bptjm-66	271	19	dehydration	dehydration	NOUN
bptjm-66	271	20	(	(	PUNCT
bptjm-66	271	21	13.3	13.3	NUM
bptjm-66	271	22	%	%	NOUN
bptjm-66	271	23	)	)	PUNCT
bptjm-66	271	24	,	,	PUNCT
bptjm-66	271	25	neuropathy	neuropathy	ADJ
bptjm-66	271	26	(	(	PUNCT
bptjm-66	271	27	13.3	13.3	NUM
bptjm-66	271	28	%	%	NOUN
bptjm-66	271	29	)	)	PUNCT
bptjm-66	271	30	,	,	PUNCT
bptjm-66	271	31	and	and	CCONJ
bptjm-66	271	32	abdominal	abdominal	ADJ
bptjm-66	271	33	pain	pain	NOUN
bptjm-66	271	34	(	(	PUNCT
bptjm-66	271	35	11.1	11.1	NUM
bptjm-66	271	36	%	%	NOUN
bptjm-66	271	37	)	)	PUNCT
bptjm-66	271	38	were	be	AUX
bptjm-66	271	39	the	the	DET
bptjm-66	271	40	most	most	ADV
bptjm-66	271	41	common	common	ADJ
bptjm-66	271	42	grade	grade	NOUN
bptjm-66	271	43	3	3	NUM
bptjm-66	271	44	toxicities	toxicity	NOUN
bptjm-66	271	45	.	.	PUNCT
bptjm-66	272	1	genexol	genexol	NOUN
bptjm-66	272	2	-	-	PUNCT
bptjm-66	272	3	pm	pm	NOUN
bptjm-66	272	4	had	have	VERB
bptjm-66	272	5	sufficient	sufficient	ADJ
bptjm-66	272	6	antitumor	antitumor	NOUN
bptjm-66	272	7	activity	activity	NOUN
bptjm-66	272	8	as	as	ADP
bptjm-66	272	9	second	second	ADJ
bptjm-66	272	10	-	-	PUNCT
bptjm-66	272	11	line	line	NOUN
bptjm-66	272	12	chemotherapy	chemotherapy	NOUN
bptjm-66	272	13	in	in	ADP
bptjm-66	272	14	patients	patient	NOUN
bptjm-66	272	15	with	with	ADP
bptjm-66	272	16	urothelial	urothelial	ADJ
bptjm-66	272	17	cancer	cancer	NOUN
bptjm-66	272	18	after	after	ADP
bptjm-66	272	19	gemcitabine	gemcitabine	NOUN
bptjm-66	272	20	-	-	PUNCT
bptjm-66	272	21	platinum	platinum	NOUN
bptjm-66	272	22	failure	failure	NOUN
bptjm-66	272	23	in	in	ADP
bptjm-66	272	24	a	a	DET
bptjm-66	272	25	phase	phase	NOUN
bptjm-66	272	26	ii	ii	NOUN
bptjm-66	272	27	study	study	NOUN
bptjm-66	272	28	in	in	ADP
bptjm-66	272	29	37	37	NUM
bptjm-66	272	30	patients	patient	NOUN
bptjm-66	272	31	with	with	ADP
bptjm-66	272	32	advanced	advanced	ADJ
bptjm-66	272	33	urothelial	urothelial	ADJ
bptjm-66	272	34	cancer	cancer	NOUN
bptjm-66	272	35	who	who	PRON
bptjm-66	272	36	had	have	AUX
bptjm-66	272	37	previously	previously	ADV
bptjm-66	272	38	received	receive	VERB
bptjm-66	272	39	gemcitabine	gemcitabine	NOUN
bptjm-66	272	40	and	and	CCONJ
bptjm-66	272	41	platinum	platinum	NOUN
bptjm-66	272	42	combination	combination	NOUN
bptjm-66	272	43	chemotherapy45	chemotherapy45	NOUN
bptjm-66	272	44	.	.	PUNCT
bptjm-66	273	1	of	of	ADP
bptjm-66	273	2	34	34	NUM
bptjm-66	273	3	evaluable	evaluable	ADJ
bptjm-66	273	4	patients	patient	NOUN
bptjm-66	273	5	,	,	PUNCT
bptjm-66	273	6	the	the	DET
bptjm-66	273	7	general	general	ADJ
bptjm-66	273	8	reaction	reaction	NOUN
bptjm-66	273	9	rate	rate	NOUN
bptjm-66	273	10	was	be	AUX
bptjm-66	273	11	21	21	NUM
bptjm-66	273	12	%	%	NOUN
bptjm-66	273	13	,	,	PUNCT
bptjm-66	273	14	with	with	ADP
bptjm-66	273	15	1	1	NUM
bptjm-66	273	16	patient	patient	NOUN
bptjm-66	273	17	in	in	ADP
bptjm-66	273	18	complete	complete	ADJ
bptjm-66	273	19	reaction	reaction	NOUN
bptjm-66	273	20	.	.	PUNCT
bptjm-66	274	1	the	the	DET
bptjm-66	274	2	median	median	PROPN
bptjm-66	274	3	pfs	pfs	PROPN
bptjm-66	274	4	was	be	AUX
bptjm-66	274	5	2.7	2.7	NUM
bptjm-66	274	6	months	month	NOUN
bptjm-66	274	7	,	,	PUNCT
bptjm-66	274	8	and	and	CCONJ
bptjm-66	274	9	the	the	DET
bptjm-66	274	10	median	median	ADJ
bptjm-66	274	11	overall	overall	ADJ
bptjm-66	274	12	survival	survival	NOUN
bptjm-66	274	13	was	be	AUX
bptjm-66	274	14	6.5	6.5	NUM
bptjm-66	274	15	months	month	NOUN
bptjm-66	274	16	.	.	PUNCT
bptjm-66	275	1	grade	grade	NOUN
bptjm-66	275	2	3/4	3/4	NUM
bptjm-66	275	3	non	non	ADJ
bptjm-66	275	4	-	-	ADJ
bptjm-66	275	5	hematologic	hematologic	ADJ
bptjm-66	275	6	poison	poison	NOUN
bptjm-66	275	7	levels	level	NOUN
bptjm-66	275	8	included	include	VERB
bptjm-66	275	9	neutropenia	neutropenia	NOUN
bptjm-66	275	10	(	(	PUNCT
bptjm-66	275	11	14.7	14.7	NUM
bptjm-66	275	12	%	%	NOUN
bptjm-66	275	13	)	)	PUNCT
bptjm-66	275	14	and	and	CCONJ
bptjm-66	275	15	contamination	contamination	NOUN
bptjm-66	275	16	(	(	PUNCT
bptjm-66	275	17	5.9	5.9	NUM
bptjm-66	275	18	%	%	NOUN
bptjm-66	275	19	)	)	PUNCT
bptjm-66	275	20	.	.	PUNCT
bptjm-66	276	1	hematologic	hematologic	NOUN
bptjm-66	276	2	toxicities	toxicity	NOUN
bptjm-66	276	3	of	of	ADP
bptjm-66	276	4	grade	grade	NOUN
bptjm-66	276	5	3/4	3/4	NUM
bptjm-66	276	6	were	be	AUX
bptjm-66	276	7	observed	observe	VERB
bptjm-66	276	8	in	in	ADP
bptjm-66	276	9	only	only	ADV
bptjm-66	276	10	one	one	NUM
bptjm-66	276	11	patient	patient	NOUN
bptjm-66	276	12	.	.	PUNCT
bptjm-66	277	1	the	the	DET
bptjm-66	277	2	low	low	ADJ
bptjm-66	277	3	rates	rate	NOUN
bptjm-66	277	4	of	of	ADP
bptjm-66	277	5	high	high	ADJ
bptjm-66	277	6	-	-	PUNCT
bptjm-66	277	7	grade	grade	NOUN
bptjm-66	277	8	toxicities	toxicity	NOUN
bptjm-66	277	9	give	give	VERB
bptjm-66	277	10	promising	promising	ADJ
bptjm-66	277	11	results	result	NOUN
bptjm-66	277	12	prospects	prospect	NOUN
bptjm-66	277	13	for	for	ADP
bptjm-66	277	14	micelles	micelle	NOUN
bptjm-66	277	15	in	in	ADP
bptjm-66	277	16	the	the	DET
bptjm-66	277	17	field	field	NOUN
bptjm-66	277	18	of	of	ADP
bptjm-66	277	19	oncology	oncology	NOUN
bptjm-66	277	20	.	.	PUNCT
bptjm-66	278	1	3.9	3.9	NUM
bptjm-66	278	2	dendrimers	dendrimer	NOUN
bptjm-66	278	3	berkeley	berkeley	PROPN
bptjm-66	278	4	pharma	pharma	PROPN
bptjm-66	278	5	tech	tech	NOUN
bptjm-66	278	6	journal	journal	NOUN
bptjm-66	278	7	of	of	ADP
bptjm-66	278	8	medicine	medicine	NOUN
bptjm-66	278	9	|	|	ADV
bptjm-66	278	10	18	18	NUM
bptjm-66	278	11	dendrimers	dendrimer	NOUN
bptjm-66	278	12	are	be	AUX
bptjm-66	278	13	large	large	ADJ
bptjm-66	278	14	branched	branched	ADJ
bptjm-66	278	15	molecules	molecule	NOUN
bptjm-66	278	16	that	that	PRON
bptjm-66	278	17	are	be	AUX
bptjm-66	278	18	composed	compose	VERB
bptjm-66	278	19	of	of	ADP
bptjm-66	278	20	generation	generation	NOUN
bptjm-66	278	21	zero	zero	NUM
bptjm-66	278	22	(	(	PUNCT
bptjm-66	278	23	the	the	DET
bptjm-66	278	24	core	core	NOUN
bptjm-66	278	25	molecule	molecule	NOUN
bptjm-66	278	26	)	)	PUNCT
bptjm-66	278	27	with	with	ADP
bptjm-66	278	28	branched	branched	ADJ
bptjm-66	278	29	polymer	polymer	NOUN
bptjm-66	278	30	chains	chain	NOUN
bptjm-66	278	31	synthesized	synthesize	VERB
bptjm-66	278	32	onto	onto	ADP
bptjm-66	278	33	the	the	DET
bptjm-66	278	34	central	central	ADJ
bptjm-66	278	35	molecule	molecule	NOUN
bptjm-66	278	36	.	.	PUNCT
bptjm-66	279	1	drugs	drug	NOUN
bptjm-66	279	2	can	can	AUX
bptjm-66	279	3	be	be	AUX
bptjm-66	279	4	integrated	integrate	VERB
bptjm-66	279	5	into	into	ADP
bptjm-66	279	6	the	the	DET
bptjm-66	279	7	various	various	ADJ
bptjm-66	279	8	branches	branch	NOUN
bptjm-66	279	9	of	of	ADP
bptjm-66	279	10	this	this	DET
bptjm-66	279	11	molecule	molecule	NOUN
bptjm-66	279	12	through	through	ADP
bptjm-66	279	13	reactions	reaction	NOUN
bptjm-66	279	14	.	.	PUNCT
bptjm-66	280	1	their	their	PRON
bptjm-66	280	2	differentiating	differentiate	VERB
bptjm-66	280	3	characteristics	characteristic	NOUN
bptjm-66	280	4	from	from	ADP
bptjm-66	280	5	other	other	ADJ
bptjm-66	280	6	nanocarriers	nanocarrier	NOUN
bptjm-66	280	7	include	include	VERB
bptjm-66	280	8	hyperbranching	hyperbranching	ADJ
bptjm-66	280	9	,	,	PUNCT
bptjm-66	280	10	well	well	ADV
bptjm-66	280	11	-	-	PUNCT
bptjm-66	280	12	defined	define	VERB
bptjm-66	280	13	spherical	spherical	ADJ
bptjm-66	280	14	structure	structure	NOUN
bptjm-66	280	15	,	,	PUNCT
bptjm-66	280	16	and	and	CCONJ
bptjm-66	280	17	high	high	ADJ
bptjm-66	280	18	compatibility	compatibility	NOUN
bptjm-66	280	19	with	with	ADP
bptjm-66	280	20	biological	biological	ADJ
bptjm-66	280	21	systems	system	NOUN
bptjm-66	280	22	.	.	PUNCT
bptjm-66	281	1	beyond	beyond	ADP
bptjm-66	281	2	operating	operate	VERB
bptjm-66	281	3	as	as	ADP
bptjm-66	281	4	a	a	DET
bptjm-66	281	5	nanocarrier	nanocarrier	NOUN
bptjm-66	281	6	,	,	PUNCT
bptjm-66	281	7	dendrimers	dendrimer	NOUN
bptjm-66	281	8	can	can	AUX
bptjm-66	281	9	also	also	ADV
bptjm-66	281	10	be	be	AUX
bptjm-66	281	11	used	use	VERB
bptjm-66	281	12	to	to	PART
bptjm-66	281	13	enhance	enhance	VERB
bptjm-66	281	14	drug	drug	NOUN
bptjm-66	281	15	solubility	solubility	NOUN
bptjm-66	281	16	and	and	CCONJ
bptjm-66	281	17	as	as	ADP
bptjm-66	281	18	a	a	DET
bptjm-66	281	19	stabilizing	stabilize	VERB
bptjm-66	281	20	agent	agent	NOUN
bptjm-66	281	21	for	for	ADP
bptjm-66	281	22	various	various	ADJ
bptjm-66	281	23	drugs	drug	NOUN
bptjm-66	281	24	.	.	PUNCT
bptjm-66	282	1	these	these	DET
bptjm-66	282	2	two	two	NUM
bptjm-66	282	3	attributes	attribute	NOUN
bptjm-66	282	4	are	be	AUX
bptjm-66	282	5	synergized	synergize	VERB
bptjm-66	282	6	when	when	SCONJ
bptjm-66	282	7	finding	find	VERB
bptjm-66	282	8	applications	application	NOUN
bptjm-66	282	9	of	of	ADP
bptjm-66	282	10	dendrimers	dendrimer	NOUN
bptjm-66	282	11	.	.	PUNCT
bptjm-66	283	1	the	the	DET
bptjm-66	283	2	most	most	ADV
bptjm-66	283	3	well	well	ADV
bptjm-66	283	4	-	-	PUNCT
bptjm-66	283	5	known	know	VERB
bptjm-66	283	6	dendrimers	dendrimer	NOUN
bptjm-66	283	7	incorporate	incorporate	VERB
bptjm-66	283	8	poly(amidoamine	poly(amidoamine	NOUN
bptjm-66	283	9	)	)	PUNCT
bptjm-66	283	10	(	(	PUNCT
bptjm-66	283	11	pamam	pamam	NOUN
bptjm-66	283	12	)	)	PUNCT
bptjm-66	283	13	dendrimers	dendrimer	NOUN
bptjm-66	283	14	,	,	PUNCT
bptjm-66	283	15	polypropylene	polypropylene	NOUN
bptjm-66	283	16	dendrimers	dendrimer	NOUN
bptjm-66	283	17	,	,	PUNCT
bptjm-66	283	18	polyesters	polyester	NOUN
bptjm-66	283	19	,	,	PUNCT
bptjm-66	283	20	and	and	CCONJ
bptjm-66	283	21	triazines	triazine	NOUN
bptjm-66	283	22	.	.	PUNCT
bptjm-66	284	1	dendrimers	dendrimer	NOUN
bptjm-66	284	2	can	can	AUX
bptjm-66	284	3	be	be	AUX
bptjm-66	284	4	conjugated	conjugate	VERB
bptjm-66	284	5	to	to	ADP
bptjm-66	284	6	various	various	ADJ
bptjm-66	284	7	molecules	molecule	NOUN
bptjm-66	284	8	in	in	ADP
bptjm-66	284	9	addition	addition	NOUN
bptjm-66	284	10	to	to	ADP
bptjm-66	284	11	the	the	DET
bptjm-66	284	12	functional	functional	ADJ
bptjm-66	284	13	groups	group	NOUN
bptjm-66	284	14	that	that	PRON
bptjm-66	284	15	are	be	AUX
bptjm-66	284	16	found	find	VERB
bptjm-66	284	17	on	on	ADP
bptjm-66	284	18	their	their	PRON
bptjm-66	284	19	external	external	ADJ
bptjm-66	284	20	surface	surface	NOUN
bptjm-66	284	21	.	.	PUNCT
bptjm-66	285	1	dendrimers	dendrimer	NOUN
bptjm-66	285	2	are	be	AUX
bptjm-66	285	3	a	a	DET
bptjm-66	285	4	productive	productive	ADJ
bptjm-66	285	5	solvency	solvency	NOUN
bptjm-66	285	6	enhancer	enhancer	NOUN
bptjm-66	285	7	of	of	ADP
bptjm-66	285	8	nsaids	nsaid	NOUN
bptjm-66	285	9	,	,	PUNCT
bptjm-66	285	10	which	which	PRON
bptjm-66	285	11	is	be	AUX
bptjm-66	285	12	enhanced	enhance	VERB
bptjm-66	285	13	by	by	ADP
bptjm-66	285	14	weak	weak	ADJ
bptjm-66	285	15	hydrogen	hydrogen	NOUN
bptjm-66	285	16	bonds	bond	NOUN
bptjm-66	285	17	provided	provide	VERB
bptjm-66	285	18	by	by	ADP
bptjm-66	285	19	branch	branch	NOUN
bptjm-66	285	20	units	unit	NOUN
bptjm-66	285	21	,	,	PUNCT
bptjm-66	285	22	and	and	CCONJ
bptjm-66	285	23	electrostatic	electrostatic	ADJ
bptjm-66	285	24	action	action	NOUN
bptjm-66	285	25	from	from	ADP
bptjm-66	285	26	surface	surface	NOUN
bptjm-66	285	27	groups	group	NOUN
bptjm-66	285	28	.	.	PUNCT
bptjm-66	286	1	koc	koc	PROPN
bptjm-66	286	2	et	et	PROPN
bptjm-66	286	3	al	al	PROPN
bptjm-66	286	4	.	.	PROPN
bptjm-66	286	5	investigated	investigate	VERB
bptjm-66	286	6	the	the	DET
bptjm-66	286	7	solubility	solubility	NOUN
bptjm-66	286	8	of	of	ADP
bptjm-66	286	9	pamam	pamam	NOUN
bptjm-66	286	10	dendritic	dendritic	ADJ
bptjm-66	286	11	macromolecules	macromolecule	NOUN
bptjm-66	286	12	loaded	load	VERB
bptjm-66	286	13	with	with	ADP
bptjm-66	286	14	nsaids	nsaid	NOUN
bptjm-66	286	15	(	(	PUNCT
bptjm-66	286	16	ketoprofen	ketoprofen	NOUN
bptjm-66	286	17	,	,	PUNCT
bptjm-66	286	18	ibuprofen	ibuprofen	NOUN
bptjm-66	286	19	,	,	PUNCT
bptjm-66	286	20	and	and	CCONJ
bptjm-66	286	21	diflunisal	diflunisal	NOUN
bptjm-66	286	22	)	)	PUNCT
bptjm-66	286	23	in	in	ADP
bptjm-66	286	24	a	a	DET
bptjm-66	286	25	buffer	buffer	NOUN
bptjm-66	286	26	solution46	solution46	NOUN
bptjm-66	286	27	.	.	PUNCT
bptjm-66	287	1	the	the	DET
bptjm-66	287	2	outcomes	outcome	NOUN
bptjm-66	287	3	showed	show	VERB
bptjm-66	287	4	that	that	SCONJ
bptjm-66	287	5	the	the	DET
bptjm-66	287	6	solvency	solvency	NOUN
bptjm-66	287	7	improvement	improvement	NOUN
bptjm-66	287	8	execution	execution	NOUN
bptjm-66	287	9	of	of	ADP
bptjm-66	287	10	hydrophobic	hydrophobic	NOUN
bptjm-66	287	11	medications	medication	NOUN
bptjm-66	287	12	in	in	ADP
bptjm-66	287	13	pamam	pamam	NOUN
bptjm-66	287	14	dendritic	dendritic	ADJ
bptjm-66	287	15	atoms	atom	NOUN
bptjm-66	287	16	was	be	AUX
bptjm-66	287	17	several	several	ADJ
bptjm-66	287	18	times	time	NOUN
bptjm-66	287	19	greater	great	ADJ
bptjm-66	287	20	than	than	ADP
bptjm-66	287	21	ethylenediamine	ethylenediamine	NOUN
bptjm-66	287	22	-	-	PUNCT
bptjm-66	287	23	cored	core	VERB
bptjm-66	287	24	pamam	pamam	NOUN
bptjm-66	287	25	dendritic	dendritic	ADJ
bptjm-66	287	26	macromolecules	macromolecule	NOUN
bptjm-66	287	27	because	because	SCONJ
bptjm-66	287	28	of	of	ADP
bptjm-66	287	29	their	their	PRON
bptjm-66	287	30	original	original	ADJ
bptjm-66	287	31	polypropylene	polypropylene	NOUN
bptjm-66	287	32	oxide	oxide	NOUN
bptjm-66	287	33	cores	core	NOUN
bptjm-66	287	34	.	.	PUNCT
bptjm-66	288	1	as	as	ADP
bptjm-66	288	2	a	a	DET
bptjm-66	288	3	result	result	NOUN
bptjm-66	288	4	,	,	PUNCT
bptjm-66	288	5	dendrimer	dendrimer	NOUN
bptjm-66	288	6	carrier	carrier	NOUN
bptjm-66	288	7	optimization	optimization	NOUN
bptjm-66	288	8	and	and	CCONJ
bptjm-66	288	9	application	application	NOUN
bptjm-66	288	10	have	have	VERB
bptjm-66	288	11	significant	significant	ADJ
bptjm-66	288	12	potential	potential	NOUN
bptjm-66	288	13	for	for	ADP
bptjm-66	288	14	pain	pain	NOUN
bptjm-66	288	15	-	-	PUNCT
bptjm-66	288	16	induced	induce	VERB
bptjm-66	288	17	inflammation	inflammation	NOUN
bptjm-66	288	18	treatment	treatment	NOUN
bptjm-66	288	19	.	.	PUNCT
bptjm-66	289	1	3.10	3.10	NUM
bptjm-66	289	2	poly(lactic	poly(lactic	PROPN
bptjm-66	289	3	-	-	PUNCT
bptjm-66	289	4	co	co	NOUN
bptjm-66	289	5	-	-	ADJ
bptjm-66	289	6	glycolic	glycolic	ADJ
bptjm-66	289	7	acid	acid	NOUN
bptjm-66	289	8	)	)	PUNCT
bptjm-66	289	9	nps	nps	PROPN
bptjm-66	289	10	(	(	PUNCT
bptjm-66	289	11	plga	plga	NOUN
bptjm-66	289	12	)	)	PUNCT
bptjm-66	289	13	nanoparticles	nanoparticle	NOUN
bptjm-66	289	14	plga	plga	VERB
bptjm-66	289	15	nanoparticles	nanoparticle	NOUN
bptjm-66	289	16	are	be	AUX
bptjm-66	289	17	synthesized	synthesize	VERB
bptjm-66	289	18	from	from	ADP
bptjm-66	289	19	lactic	lactic	ADJ
bptjm-66	289	20	and	and	CCONJ
bptjm-66	289	21	glycolic	glycolic	NOUN
bptjm-66	289	22	acids	acid	NOUN
bptjm-66	289	23	,	,	PUNCT
bptjm-66	289	24	with	with	ADP
bptjm-66	289	25	customizability	customizability	NOUN
bptjm-66	289	26	deriving	derive	VERB
bptjm-66	289	27	from	from	ADP
bptjm-66	289	28	the	the	DET
bptjm-66	289	29	myriad	myriad	NOUN
bptjm-66	289	30	of	of	ADP
bptjm-66	289	31	lactic	lactic	ADJ
bptjm-66	289	32	and	and	CCONJ
bptjm-66	289	33	glycolic	glycolic	NOUN
bptjm-66	289	34	acid	acid	NOUN
bptjm-66	289	35	concentrations	concentration	NOUN
bptjm-66	289	36	.	.	PUNCT
bptjm-66	290	1	the	the	DET
bptjm-66	290	2	differentiating	differentiate	VERB
bptjm-66	290	3	factor	factor	NOUN
bptjm-66	290	4	of	of	ADP
bptjm-66	290	5	this	this	DET
bptjm-66	290	6	nanocarrier	nanocarrier	NOUN
bptjm-66	290	7	lies	lie	VERB
bptjm-66	290	8	in	in	ADP
bptjm-66	290	9	its	its	PRON
bptjm-66	290	10	simple	simple	ADJ
bptjm-66	290	11	preparation	preparation	NOUN
bptjm-66	290	12	,	,	PUNCT
bptjm-66	290	13	biodegradability	biodegradability	NOUN
bptjm-66	290	14	,	,	PUNCT
bptjm-66	290	15	and	and	CCONJ
bptjm-66	290	16	high	high	ADJ
bptjm-66	290	17	drug	drug	NOUN
bptjm-66	290	18	-	-	PUNCT
bptjm-66	290	19	loading	loading	NOUN
bptjm-66	290	20	capacity	capacity	NOUN
bptjm-66	290	21	.	.	PUNCT
bptjm-66	291	1	it	it	PRON
bptjm-66	291	2	also	also	ADV
bptjm-66	291	3	demonstrates	demonstrate	VERB
bptjm-66	291	4	great	great	ADJ
bptjm-66	291	5	control	control	NOUN
bptjm-66	291	6	over	over	ADP
bptjm-66	291	7	drug	drug	NOUN
bptjm-66	291	8	release	release	NOUN
bptjm-66	291	9	.	.	PUNCT
bptjm-66	292	1	a	a	DET
bptjm-66	292	2	study	study	NOUN
bptjm-66	292	3	conducted	conduct	VERB
bptjm-66	292	4	on	on	ADP
bptjm-66	292	5	the	the	DET
bptjm-66	292	6	release	release	NOUN
bptjm-66	292	7	of	of	ADP
bptjm-66	292	8	ketamine	ketamine	PROPN
bptjm-66	292	9	through	through	ADP
bptjm-66	292	10	plga	plga	NOUN
bptjm-66	292	11	nanoparticles	nanoparticle	NOUN
bptjm-66	292	12	was	be	AUX
bptjm-66	292	13	conducted	conduct	VERB
bptjm-66	292	14	by	by	ADP
bptjm-66	292	15	han	han	PROPN
bptjm-66	292	16	et	et	PROPN
bptjm-66	292	17	al	al	PROPN
bptjm-66	292	18	;	;	PUNCT
bptjm-66	292	19	biocompatible	biocompatible	ADJ
bptjm-66	292	20	and	and	CCONJ
bptjm-66	292	21	biodegradable	biodegradable	ADJ
bptjm-66	292	22	ketamine	ketamine	NOUN
bptjm-66	292	23	-	-	PUNCT
bptjm-66	292	24	loaded	load	VERB
bptjm-66	292	25	polyethylene	polyethylene	NOUN
bptjm-66	292	26	-	-	PUNCT
bptjm-66	292	27	glycol	glycol	NOUN
bptjm-66	292	28	plga	plga	NOUN
bptjm-66	292	29	nanoparticles	nanoparticle	NOUN
bptjm-66	292	30	were	be	AUX
bptjm-66	292	31	tested	test	VERB
bptjm-66	292	32	in	in	ADP
bptjm-66	292	33	pain	pain	NOUN
bptjm-66	292	34	treatment	treatment	NOUN
bptjm-66	292	35	in	in	ADP
bptjm-66	292	36	the	the	DET
bptjm-66	292	37	context	context	NOUN
bptjm-66	292	38	of	of	ADP
bptjm-66	292	39	pain	pain	PROPN
bptjm-66	292	40	medicine47	medicine47	PROPN
bptjm-66	292	41	.	.	PUNCT
bptjm-66	293	1	the	the	DET
bptjm-66	293	2	results	result	NOUN
bptjm-66	293	3	demonstrated	demonstrate	VERB
bptjm-66	293	4	a	a	DET
bptjm-66	293	5	41.8	41.8	NUM
bptjm-66	293	6	%	%	NOUN
bptjm-66	293	7	drug	drug	NOUN
bptjm-66	293	8	loading	loading	NOUN
bptjm-66	293	9	,	,	PUNCT
bptjm-66	293	10	with	with	ADP
bptjm-66	293	11	preservation	preservation	NOUN
bptjm-66	293	12	of	of	ADP
bptjm-66	293	13	the	the	DET
bptjm-66	293	14	drug	drug	NOUN
bptjm-66	293	15	for	for	ADP
bptjm-66	293	16	up	up	ADP
bptjm-66	293	17	to	to	PART
bptjm-66	293	18	7	7	NUM
bptjm-66	293	19	days	day	NOUN
bptjm-66	293	20	and	and	CCONJ
bptjm-66	293	21	controlled	control	VERB
bptjm-66	293	22	release	release	NOUN
bptjm-66	293	23	for	for	ADP
bptjm-66	293	24	up	up	ADP
bptjm-66	293	25	to	to	PART
bptjm-66	293	26	21	21	NUM
bptjm-66	293	27	berkeley	berkeley	PROPN
bptjm-66	293	28	pharma	pharma	PROPN
bptjm-66	293	29	tech	tech	NOUN
bptjm-66	293	30	journal	journal	NOUN
bptjm-66	293	31	of	of	ADP
bptjm-66	293	32	medicine	medicine	NOUN
bptjm-66	293	33	|	|	ADV
bptjm-66	293	34	19	19	NUM
bptjm-66	293	35	days	day	NOUN
bptjm-66	293	36	.	.	PUNCT
bptjm-66	294	1	furthermore	furthermore	ADV
bptjm-66	294	2	,	,	PUNCT
bptjm-66	294	3	the	the	DET
bptjm-66	294	4	decay	decay	NOUN
bptjm-66	294	5	of	of	ADP
bptjm-66	294	6	ketamine	ketamine	PROPN
bptjm-66	294	7	below	below	ADP
bptjm-66	294	8	the	the	DET
bptjm-66	294	9	lower	low	ADJ
bptjm-66	294	10	limit	limit	NOUN
bptjm-66	294	11	of	of	ADP
bptjm-66	294	12	quantitation	quantitation	NOUN
bptjm-66	294	13	rose	rise	VERB
bptjm-66	294	14	to	to	ADP
bptjm-66	294	15	~103	~103	X
bptjm-66	294	16	hours	hour	NOUN
bptjm-66	294	17	and	and	CCONJ
bptjm-66	294	18	~80	~80	NOUN
bptjm-66	294	19	hours	hour	NOUN
bptjm-66	294	20	with	with	ADP
bptjm-66	294	21	plga	plga	NOUN
bptjm-66	294	22	in	in	ADP
bptjm-66	294	23	comparison	comparison	NOUN
bptjm-66	294	24	to	to	ADP
bptjm-66	294	25	only	only	ADV
bptjm-66	294	26	24	24	NUM
bptjm-66	294	27	hours	hour	NOUN
bptjm-66	294	28	when	when	SCONJ
bptjm-66	294	29	injected	inject	VERB
bptjm-66	294	30	intravenously	intravenously	ADV
bptjm-66	294	31	without	without	ADP
bptjm-66	294	32	a	a	DET
bptjm-66	294	33	nanocarrier	nanocarrier	NOUN
bptjm-66	294	34	.	.	PUNCT
bptjm-66	295	1	further	further	ADJ
bptjm-66	295	2	optimization	optimization	NOUN
bptjm-66	295	3	of	of	ADP
bptjm-66	295	4	drug	drug	NOUN
bptjm-66	295	5	distribution	distribution	NOUN
bptjm-66	295	6	in	in	ADP
bptjm-66	295	7	the	the	DET
bptjm-66	295	8	polymer	polymer	NOUN
bptjm-66	295	9	matrix	matrix	NOUN
bptjm-66	295	10	as	as	ADV
bptjm-66	295	11	well	well	ADV
bptjm-66	295	12	as	as	ADP
bptjm-66	295	13	plga	plga	NOUN
bptjm-66	295	14	composition	composition	NOUN
bptjm-66	295	15	is	be	AUX
bptjm-66	295	16	being	be	AUX
bptjm-66	295	17	performed	perform	VERB
bptjm-66	295	18	to	to	PART
bptjm-66	295	19	better	well	ADV
bptjm-66	295	20	formulate	formulate	VERB
bptjm-66	295	21	drugs	drug	NOUN
bptjm-66	295	22	with	with	ADP
bptjm-66	295	23	broader	broad	ADJ
bptjm-66	295	24	and	and	CCONJ
bptjm-66	295	25	more	more	ADV
bptjm-66	295	26	effective	effective	ADJ
bptjm-66	295	27	applications	application	NOUN
bptjm-66	295	28	.	.	PUNCT
bptjm-66	296	1	3.11	3.11	NUM
bptjm-66	296	2	other	other	ADJ
bptjm-66	296	3	nanocarriers	nanocarrier	NOUN
bptjm-66	296	4	there	there	PRON
bptjm-66	296	5	remains	remain	VERB
bptjm-66	296	6	a	a	DET
bptjm-66	296	7	multitude	multitude	NOUN
bptjm-66	296	8	of	of	ADP
bptjm-66	296	9	nanocarriers	nanocarrier	NOUN
bptjm-66	296	10	currently	currently	ADV
bptjm-66	296	11	being	be	AUX
bptjm-66	296	12	explored	explore	VERB
bptjm-66	296	13	for	for	ADP
bptjm-66	296	14	their	their	PRON
bptjm-66	296	15	therapeutic	therapeutic	ADJ
bptjm-66	296	16	applications	application	NOUN
bptjm-66	296	17	.	.	PUNCT
bptjm-66	297	1	to	to	PART
bptjm-66	297	2	list	list	VERB
bptjm-66	297	3	a	a	DET
bptjm-66	297	4	few	few	ADJ
bptjm-66	297	5	,	,	PUNCT
bptjm-66	297	6	thermogels	thermogel	NOUN
bptjm-66	297	7	,	,	PUNCT
bptjm-66	297	8	emulgels	emulgel	NOUN
bptjm-66	297	9	,	,	PUNCT
bptjm-66	297	10	various	various	ADJ
bptjm-66	297	11	films	film	NOUN
bptjm-66	297	12	,	,	PUNCT
bptjm-66	297	13	and	and	CCONJ
bptjm-66	297	14	silicon	silicon	NOUN
bptjm-66	297	15	nanoparticles	nanoparticle	NOUN
bptjm-66	297	16	are	be	AUX
bptjm-66	297	17	currently	currently	ADV
bptjm-66	297	18	being	be	AUX
bptjm-66	297	19	researched	research	VERB
bptjm-66	297	20	.	.	PUNCT
bptjm-66	298	1	it	it	PRON
bptjm-66	298	2	is	be	AUX
bptjm-66	298	3	important	important	ADJ
bptjm-66	298	4	to	to	PART
bptjm-66	298	5	note	note	VERB
bptjm-66	298	6	the	the	DET
bptjm-66	298	7	limitations	limitation	NOUN
bptjm-66	298	8	when	when	SCONJ
bptjm-66	298	9	it	it	PRON
bptjm-66	298	10	comes	come	VERB
bptjm-66	298	11	to	to	ADP
bptjm-66	298	12	nanotechnology	nanotechnology	NOUN
bptjm-66	298	13	,	,	PUNCT
bptjm-66	298	14	including	include	VERB
bptjm-66	298	15	stability	stability	NOUN
bptjm-66	298	16	,	,	PUNCT
bptjm-66	298	17	cytotoxicity	cytotoxicity	NOUN
bptjm-66	298	18	,	,	PUNCT
bptjm-66	298	19	and	and	CCONJ
bptjm-66	298	20	solubility	solubility	NOUN
bptjm-66	298	21	,	,	PUNCT
bptjm-66	298	22	as	as	SCONJ
bptjm-66	298	23	they	they	PRON
bptjm-66	298	24	pose	pose	VERB
bptjm-66	298	25	great	great	ADJ
bptjm-66	298	26	barriers	barrier	NOUN
bptjm-66	298	27	to	to	ADP
bptjm-66	298	28	delivering	deliver	VERB
bptjm-66	298	29	many	many	ADJ
bptjm-66	298	30	drugs	drug	NOUN
bptjm-66	298	31	.	.	PUNCT
bptjm-66	299	1	4	4	X
bptjm-66	299	2	.	.	X
bptjm-66	299	3	pharmaceutical	pharmaceutical	NOUN
bptjm-66	299	4	remedies	remedy	NOUN
bptjm-66	299	5	advancements	advancement	NOUN
bptjm-66	299	6	4.1	4.1	NUM
bptjm-66	299	7	myofascial	myofascial	ADJ
bptjm-66	299	8	release	release	NOUN
bptjm-66	299	9	myofascial	myofascial	ADJ
bptjm-66	299	10	release	release	NOUN
bptjm-66	299	11	is	be	AUX
bptjm-66	299	12	an	an	DET
bptjm-66	299	13	external	external	ADJ
bptjm-66	299	14	method	method	NOUN
bptjm-66	299	15	that	that	PRON
bptjm-66	299	16	refers	refer	VERB
bptjm-66	299	17	to	to	ADP
bptjm-66	299	18	the	the	DET
bptjm-66	299	19	manual	manual	ADJ
bptjm-66	299	20	application	application	NOUN
bptjm-66	299	21	of	of	ADP
bptjm-66	299	22	a	a	DET
bptjm-66	299	23	low	low	ADJ
bptjm-66	299	24	-	-	PUNCT
bptjm-66	299	25	load	load	NOUN
bptjm-66	299	26	,	,	PUNCT
bptjm-66	299	27	long	long	ADJ
bptjm-66	299	28	-	-	PUNCT
bptjm-66	299	29	duration	duration	NOUN
bptjm-66	299	30	stretch	stretch	NOUN
bptjm-66	299	31	of	of	ADP
bptjm-66	299	32	the	the	DET
bptjm-66	299	33	myofascial	myofascial	ADJ
bptjm-66	299	34	complex	complex	NOUN
bptjm-66	299	35	.	.	PUNCT
bptjm-66	300	1	its	its	PRON
bptjm-66	300	2	objective	objective	NOUN
bptjm-66	300	3	is	be	AUX
bptjm-66	300	4	to	to	PART
bptjm-66	300	5	restore	restore	VERB
bptjm-66	300	6	the	the	DET
bptjm-66	300	7	ideal	ideal	ADJ
bptjm-66	300	8	length	length	NOUN
bptjm-66	300	9	of	of	ADP
bptjm-66	300	10	the	the	DET
bptjm-66	300	11	fascial	fascial	ADJ
bptjm-66	300	12	tissue	tissue	NOUN
bptjm-66	300	13	to	to	PART
bptjm-66	300	14	decrease	decrease	VERB
bptjm-66	300	15	perceived	perceive	VERB
bptjm-66	300	16	pain	pain	NOUN
bptjm-66	300	17	and	and	CCONJ
bptjm-66	300	18	enhance	enhance	VERB
bptjm-66	300	19	mobility	mobility	NOUN
bptjm-66	300	20	.	.	PUNCT
bptjm-66	301	1	this	this	DET
bptjm-66	301	2	method	method	NOUN
bptjm-66	301	3	targets	target	VERB
bptjm-66	301	4	fascia	fascia	NOUN
bptjm-66	301	5	tissue	tissue	NOUN
bptjm-66	301	6	and	and	CCONJ
bptjm-66	301	7	other	other	ADJ
bptjm-66	301	8	associated	associate	VERB
bptjm-66	301	9	soft	soft	ADJ
bptjm-66	301	10	tissues	tissue	NOUN
bptjm-66	301	11	.	.	PUNCT
bptjm-66	302	1	fascia	fascia	NOUN
bptjm-66	302	2	tissue	tissue	NOUN
bptjm-66	302	3	is	be	AUX
bptjm-66	302	4	considered	consider	VERB
bptjm-66	302	5	connective	connective	ADJ
bptjm-66	302	6	tissue	tissue	NOUN
bptjm-66	302	7	and	and	CCONJ
bptjm-66	302	8	it	it	PRON
bptjm-66	302	9	is	be	AUX
bptjm-66	302	10	not	not	PART
bptjm-66	302	11	just	just	ADV
bptjm-66	302	12	the	the	DET
bptjm-66	302	13	muscular	muscular	ADJ
bptjm-66	302	14	aspect	aspect	NOUN
bptjm-66	302	15	but	but	CCONJ
bptjm-66	302	16	the	the	DET
bptjm-66	302	17	connective	connective	ADJ
bptjm-66	302	18	tissue	tissue	NOUN
bptjm-66	302	19	that	that	PRON
bptjm-66	302	20	also	also	ADV
bptjm-66	302	21	surrounds	surround	VERB
bptjm-66	302	22	organs48	organs48	NOUN
bptjm-66	302	23	.	.	PUNCT
bptjm-66	303	1	overall	overall	ADJ
bptjm-66	303	2	fascia	fascia	NOUN
bptjm-66	303	3	tissue	tissue	NOUN
bptjm-66	303	4	goes	go	VERB
bptjm-66	303	5	under	under	ADP
bptjm-66	303	6	a	a	DET
bptjm-66	303	7	lot	lot	NOUN
bptjm-66	303	8	of	of	ADP
bptjm-66	303	9	stress	stress	NOUN
bptjm-66	303	10	from	from	ADP
bptjm-66	303	11	the	the	DET
bptjm-66	303	12	body	body	NOUN
bptjm-66	303	13	and	and	CCONJ
bptjm-66	303	14	may	may	AUX
bptjm-66	303	15	become	become	VERB
bptjm-66	303	16	increasingly	increasingly	ADV
bptjm-66	303	17	rigid	rigid	ADJ
bptjm-66	303	18	over	over	ADP
bptjm-66	303	19	time	time	NOUN
bptjm-66	303	20	.	.	PUNCT
bptjm-66	304	1	in	in	ADP
bptjm-66	304	2	addition	addition	NOUN
bptjm-66	304	3	,	,	PUNCT
bptjm-66	304	4	fascia	fascia	NOUN
bptjm-66	304	5	tissue	tissue	NOUN
bptjm-66	304	6	can	can	AUX
bptjm-66	304	7	be	be	AUX
bptjm-66	304	8	elastic	elastic	ADJ
bptjm-66	304	9	and	and	CCONJ
bptjm-66	304	10	go	go	VERB
bptjm-66	304	11	in	in	ADV
bptjm-66	304	12	and	and	CCONJ
bptjm-66	304	13	out	out	ADP
bptjm-66	304	14	of	of	ADP
bptjm-66	304	15	the	the	DET
bptjm-66	304	16	normal	normal	ADJ
bptjm-66	304	17	shape	shape	NOUN
bptjm-66	304	18	,	,	PUNCT
bptjm-66	304	19	but	but	CCONJ
bptjm-66	304	20	over	over	ADP
bptjm-66	304	21	time	time	NOUN
bptjm-66	304	22	the	the	DET
bptjm-66	304	23	overuse	overuse	NOUN
bptjm-66	304	24	may	may	AUX
bptjm-66	304	25	gradually	gradually	ADV
bptjm-66	304	26	deform	deform	VERB
bptjm-66	304	27	the	the	DET
bptjm-66	304	28	tissue	tissue	NOUN
bptjm-66	304	29	,	,	PUNCT
bptjm-66	304	30	allowing	allow	VERB
bptjm-66	304	31	the	the	DET
bptjm-66	304	32	rigidness	rigidness	NOUN
bptjm-66	304	33	to	to	PART
bptjm-66	304	34	take	take	VERB
bptjm-66	304	35	place49	place49	NOUN
bptjm-66	304	36	.	.	PUNCT
bptjm-66	305	1	tissue	tissue	NOUN
bptjm-66	305	2	rigidity	rigidity	NOUN
bptjm-66	305	3	or	or	CCONJ
bptjm-66	305	4	deformity	deformity	NOUN
bptjm-66	305	5	may	may	AUX
bptjm-66	305	6	contribute	contribute	VERB
bptjm-66	305	7	pain	pain	NOUN
bptjm-66	305	8	for	for	ADP
bptjm-66	305	9	an	an	DET
bptjm-66	305	10	individual	individual	NOUN
bptjm-66	305	11	.	.	PUNCT
bptjm-66	306	1	the	the	DET
bptjm-66	306	2	method	method	NOUN
bptjm-66	306	3	of	of	ADP
bptjm-66	306	4	myofascial	myofascial	ADJ
bptjm-66	306	5	release	release	NOUN
bptjm-66	306	6	is	be	AUX
bptjm-66	306	7	to	to	PART
bptjm-66	306	8	target	target	VERB
bptjm-66	306	9	those	those	DET
bptjm-66	306	10	tightened	tighten	VERB
bptjm-66	306	11	points	point	NOUN
bptjm-66	306	12	of	of	ADP
bptjm-66	306	13	fascia	fascia	NOUN
bptjm-66	306	14	tissue	tissue	NOUN
bptjm-66	306	15	and	and	CCONJ
bptjm-66	306	16	either	either	CCONJ
bptjm-66	306	17	the	the	DET
bptjm-66	306	18	individual	individual	ADJ
bptjm-66	306	19	or	or	CCONJ
bptjm-66	306	20	clinician	clinician	NOUN
bptjm-66	306	21	will	will	AUX
bptjm-66	306	22	add	add	VERB
bptjm-66	306	23	pressure	pressure	NOUN
bptjm-66	306	24	to	to	ADP
bptjm-66	306	25	the	the	DET
bptjm-66	306	26	pain	pain	NOUN
bptjm-66	306	27	point	point	NOUN
bptjm-66	306	28	and	and	CCONJ
bptjm-66	306	29	hold	hold	VERB
bptjm-66	306	30	the	the	DET
bptjm-66	306	31	pressure	pressure	NOUN
bptjm-66	306	32	until	until	SCONJ
bptjm-66	306	33	there	there	PRON
bptjm-66	306	34	is	be	VERB
bptjm-66	306	35	no	no	PRON
bptjm-66	306	36	longer	long	ADV
bptjm-66	306	37	any	any	DET
bptjm-66	306	38	resistance	resistance	NOUN
bptjm-66	306	39	from	from	ADP
bptjm-66	306	40	the	the	DET
bptjm-66	306	41	tissue50	tissue50	NOUN
bptjm-66	306	42	.	.	PUNCT
bptjm-66	307	1	when	when	SCONJ
bptjm-66	307	2	myofascial	myofascial	ADJ
bptjm-66	307	3	release	release	NOUN
bptjm-66	307	4	is	be	AUX
bptjm-66	307	5	used	use	VERB
bptjm-66	307	6	by	by	ADP
bptjm-66	307	7	the	the	DET
bptjm-66	307	8	individual	individual	NOUN
bptjm-66	307	9	,	,	PUNCT
bptjm-66	307	10	the	the	DET
bptjm-66	307	11	tools	tool	NOUN
bptjm-66	307	12	commonly	commonly	ADV
bptjm-66	307	13	used	use	VERB
bptjm-66	307	14	are	be	AUX
bptjm-66	307	15	a	a	DET
bptjm-66	307	16	foam	foam	NOUN
bptjm-66	307	17	roller	roller	NOUN
bptjm-66	307	18	and	and	CCONJ
bptjm-66	307	19	roller	roller	NOUN
bptjm-66	307	20	massager51	massager51	NOUN
bptjm-66	307	21	.	.	PUNCT
bptjm-66	308	1	variety	variety	NOUN
bptjm-66	308	2	of	of	ADP
bptjm-66	308	3	motions	motion	NOUN
bptjm-66	308	4	and	and	CCONJ
bptjm-66	308	5	movements	movement	NOUN
bptjm-66	308	6	used	use	VERB
bptjm-66	308	7	with	with	ADP
bptjm-66	308	8	each	each	PRON
bptjm-66	308	9	of	of	ADP
bptjm-66	308	10	these	these	DET
bptjm-66	308	11	tools	tool	NOUN
bptjm-66	308	12	target	target	VERB
bptjm-66	308	13	specific	specific	ADJ
bptjm-66	308	14	painful	painful	ADJ
bptjm-66	308	15	areas	area	NOUN
bptjm-66	308	16	.	.	PUNCT
bptjm-66	309	1	berkeley	berkeley	PROPN
bptjm-66	309	2	pharma	pharma	PROPN
bptjm-66	309	3	tech	tech	PROPN
bptjm-66	309	4	journal	journal	NOUN
bptjm-66	309	5	of	of	ADP
bptjm-66	309	6	medicine	medicine	NOUN
bptjm-66	309	7	|	|	ADV
bptjm-66	309	8	20	20	NUM
bptjm-66	309	9	figure	figure	NOUN
bptjm-66	309	10	5	5	NUM
bptjm-66	309	11	.	.	PUNCT
bptjm-66	309	12	fascia	fascia	NOUN
bptjm-66	309	13	tissue	tissue	NOUN
bptjm-66	309	14	normal	normal	ADJ
bptjm-66	309	15	vs	vs	ADP
bptjm-66	309	16	abnormal	abnormal	ADJ
bptjm-66	309	17	shape	shape	NOUN
bptjm-66	309	18	a	a	DET
bptjm-66	309	19	clinical	clinical	ADJ
bptjm-66	309	20	,	,	PUNCT
bptjm-66	309	21	double	double	ADJ
bptjm-66	309	22	-	-	PUNCT
bptjm-66	309	23	blind	blind	ADJ
bptjm-66	309	24	,	,	PUNCT
bptjm-66	309	25	parallel	parallel	ADJ
bptjm-66	309	26	sham	sham	NOUN
bptjm-66	309	27	-	-	PUNCT
bptjm-66	309	28	controlled	control	VERB
bptjm-66	309	29	trial	trial	NOUN
bptjm-66	309	30	with	with	ADP
bptjm-66	309	31	a	a	DET
bptjm-66	309	32	balanced	balanced	ADJ
bptjm-66	309	33	randomization	randomization	NOUN
bptjm-66	309	34	trial	trial	NOUN
bptjm-66	309	35	performed	perform	VERB
bptjm-66	309	36	in	in	ADP
bptjm-66	309	37	2021	2021	NUM
bptjm-66	309	38	investigated	investigate	VERB
bptjm-66	309	39	the	the	DET
bptjm-66	309	40	magnitude	magnitude	NOUN
bptjm-66	309	41	of	of	ADP
bptjm-66	309	42	myofascial	myofascial	ADJ
bptjm-66	309	43	release	release	NOUN
bptjm-66	309	44	’s	’s	PART
bptjm-66	309	45	relief	relief	NOUN
bptjm-66	309	46	on	on	ADP
bptjm-66	309	47	chronic	chronic	PROPN
bptjm-66	309	48	lower	low	ADJ
bptjm-66	309	49	back	back	NOUN
bptjm-66	309	50	pain	pain	NOUN
bptjm-66	309	51	(	(	PUNCT
bptjm-66	309	52	clbp)52	clbp)52	PROPN
bptjm-66	309	53	.	.	PUNCT
bptjm-66	310	1	in	in	ADP
bptjm-66	310	2	this	this	DET
bptjm-66	310	3	trial	trial	NOUN
bptjm-66	310	4	,	,	PUNCT
bptjm-66	310	5	fifty	fifty	NUM
bptjm-66	310	6	-	-	PUNCT
bptjm-66	310	7	four	four	NUM
bptjm-66	310	8	participants	participant	NOUN
bptjm-66	310	9	between	between	ADP
bptjm-66	310	10	the	the	DET
bptjm-66	310	11	ages	age	NOUN
bptjm-66	310	12	of	of	ADP
bptjm-66	310	13	eighteen	eighteen	NUM
bptjm-66	310	14	and	and	CCONJ
bptjm-66	310	15	sixty	sixty	NUM
bptjm-66	310	16	years	year	NOUN
bptjm-66	310	17	old	old	ADJ
bptjm-66	310	18	diagnosed	diagnose	VERB
bptjm-66	310	19	with	with	ADP
bptjm-66	310	20	nonspecific	nonspecific	ADJ
bptjm-66	310	21	clbp	clbp	NOUN
bptjm-66	310	22	for	for	ADP
bptjm-66	310	23	at	at	ADV
bptjm-66	310	24	least	least	ADV
bptjm-66	310	25	three	three	NUM
bptjm-66	310	26	months	month	NOUN
bptjm-66	310	27	were	be	AUX
bptjm-66	310	28	chosen	choose	VERB
bptjm-66	310	29	.	.	PUNCT
bptjm-66	311	1	these	these	DET
bptjm-66	311	2	participants	participant	NOUN
bptjm-66	311	3	were	be	AUX
bptjm-66	311	4	then	then	ADV
bptjm-66	311	5	divided	divide	VERB
bptjm-66	311	6	into	into	ADP
bptjm-66	311	7	two	two	NUM
bptjm-66	311	8	groups	group	NOUN
bptjm-66	311	9	:	:	PUNCT
bptjm-66	311	10	myofascial	myofascial	ADJ
bptjm-66	311	11	release	release	NOUN
bptjm-66	311	12	(	(	PUNCT
bptjm-66	311	13	n=27	n=27	PROPN
bptjm-66	311	14	)	)	PUNCT
bptjm-66	311	15	and	and	CCONJ
bptjm-66	311	16	sham	sham	ADJ
bptjm-66	311	17	(	(	PUNCT
bptjm-66	311	18	n=27	n=27	PROPN
bptjm-66	311	19	)	)	PUNCT
bptjm-66	311	20	with	with	ADP
bptjm-66	311	21	a	a	DET
bptjm-66	311	22	random	random	ADJ
bptjm-66	311	23	number	number	NOUN
bptjm-66	311	24	generator	generator	NOUN
bptjm-66	311	25	.	.	PUNCT
bptjm-66	312	1	patients	patient	NOUN
bptjm-66	312	2	’	'	PUNCT
bptjm-66	312	3	pain	pain	NOUN
bptjm-66	312	4	was	be	AUX
bptjm-66	312	5	measured	measure	VERB
bptjm-66	312	6	through	through	ADP
bptjm-66	312	7	the	the	DET
bptjm-66	312	8	short	short	ADJ
bptjm-66	312	9	form	form	NOUN
bptjm-66	312	10	mcgill	mcgill	PROPN
bptjm-66	312	11	pain	pain	NOUN
bptjm-66	312	12	questionnaire	questionnaire	NOUN
bptjm-66	312	13	(	(	PUNCT
bptjm-66	312	14	sf	sf	NOUN
bptjm-66	312	15	-	-	PUNCT
bptjm-66	312	16	mpq	mpq	NOUN
bptjm-66	312	17	)	)	PUNCT
bptjm-66	312	18	and	and	CCONJ
bptjm-66	312	19	visual	visual	ADJ
bptjm-66	312	20	analog	analog	NOUN
bptjm-66	312	21	scale	scale	NOUN
bptjm-66	312	22	(	(	PUNCT
bptjm-66	312	23	vas	vas	NOUN
bptjm-66	312	24	)	)	PUNCT
bptjm-66	312	25	and	and	CCONJ
bptjm-66	312	26	disability	disability	NOUN
bptjm-66	312	27	was	be	AUX
bptjm-66	312	28	measured	measure	VERB
bptjm-66	312	29	with	with	ADP
bptjm-66	312	30	the	the	DET
bptjm-66	312	31	roland	roland	PROPN
bptjm-66	312	32	morris	morris	PROPN
bptjm-66	312	33	questionnaire	questionnaire	NOUN
bptjm-66	312	34	.	.	PUNCT
bptjm-66	313	1	the	the	DET
bptjm-66	313	2	trial	trial	NOUN
bptjm-66	313	3	showed	show	VERB
bptjm-66	313	4	a	a	DET
bptjm-66	313	5	significant	significant	ADJ
bptjm-66	313	6	improvement	improvement	NOUN
bptjm-66	313	7	in	in	ADP
bptjm-66	313	8	pain	pain	NOUN
bptjm-66	313	9	,	,	PUNCT
bptjm-66	313	10	as	as	SCONJ
bptjm-66	313	11	displayed	display	VERB
bptjm-66	313	12	with	with	ADP
bptjm-66	313	13	the	the	DET
bptjm-66	313	14	sf	sf	PROPN
bptjm-66	313	15	-	-	PUNCT
bptjm-66	313	16	mpq	mpq	PROPN
bptjm-66	313	17	compared	compare	VERB
bptjm-66	313	18	to	to	ADP
bptjm-66	313	19	the	the	DET
bptjm-66	313	20	sham	sham	ADJ
bptjm-66	313	21	group	group	NOUN
bptjm-66	313	22	while	while	SCONJ
bptjm-66	313	23	showing	show	VERB
bptjm-66	313	24	no	no	DET
bptjm-66	313	25	significant	significant	ADJ
bptjm-66	313	26	difference	difference	NOUN
bptjm-66	313	27	in	in	ADP
bptjm-66	313	28	vas	vas	PROPN
bptjm-66	313	29	.	.	PROPN
bptjm-66	313	30	4.2	4.2	NUM
bptjm-66	313	31	tens	ten	NOUN
bptjm-66	313	32	transcutaneous	transcutaneous	ADJ
bptjm-66	313	33	electrical	electrical	ADJ
bptjm-66	313	34	nerve	nerve	NOUN
bptjm-66	313	35	stimulation	stimulation	NOUN
bptjm-66	313	36	(	(	PUNCT
bptjm-66	313	37	tens	ten	NOUN
bptjm-66	313	38	)	)	PUNCT
bptjm-66	313	39	is	be	AUX
bptjm-66	313	40	an	an	DET
bptjm-66	313	41	external	external	ADJ
bptjm-66	313	42	non	non	ADJ
bptjm-66	313	43	-	-	ADJ
bptjm-66	313	44	invasive	invasive	ADJ
bptjm-66	313	45	treatment	treatment	NOUN
bptjm-66	313	46	used	use	VERB
bptjm-66	313	47	to	to	PART
bptjm-66	313	48	treat	treat	VERB
bptjm-66	313	49	neuropathic	neuropathic	ADJ
bptjm-66	313	50	and	and	CCONJ
bptjm-66	313	51	nociceptive	nociceptive	ADJ
bptjm-66	313	52	pain53	pain53	NOUN
bptjm-66	313	53	.	.	PUNCT
bptjm-66	314	1	tens	ten	NOUN
bptjm-66	314	2	,	,	PUNCT
bptjm-66	314	3	in	in	ADP
bptjm-66	314	4	practice	practice	NOUN
bptjm-66	314	5	,	,	PUNCT
bptjm-66	314	6	is	be	AUX
bptjm-66	314	7	an	an	DET
bptjm-66	314	8	inexpensive	inexpensive	ADJ
bptjm-66	314	9	mode	mode	NOUN
bptjm-66	314	10	of	of	ADP
bptjm-66	314	11	electrically	electrically	ADV
bptjm-66	314	12	stimulating	stimulate	VERB
bptjm-66	314	13	targeted	targeted	ADJ
bptjm-66	314	14	tissues	tissue	NOUN
bptjm-66	314	15	that	that	PRON
bptjm-66	314	16	excite	excite	VERB
bptjm-66	314	17	a	a	DET
bptjm-66	314	18	neuronal	neuronal	ADJ
bptjm-66	314	19	complex	complex	NOUN
bptjm-66	314	20	.	.	PUNCT
bptjm-66	315	1	the	the	DET
bptjm-66	315	2	most	most	ADV
bptjm-66	315	3	common	common	ADJ
bptjm-66	315	4	form	form	NOUN
bptjm-66	315	5	of	of	ADP
bptjm-66	315	6	tens	ten	NOUN
bptjm-66	315	7	can	can	AUX
bptjm-66	315	8	be	be	AUX
bptjm-66	315	9	found	find	VERB
bptjm-66	315	10	as	as	ADP
bptjm-66	315	11	a	a	DET
bptjm-66	315	12	small	small	ADJ
bptjm-66	315	13	battery	battery	NOUN
bptjm-66	315	14	-	-	PUNCT
bptjm-66	315	15	run	run	NOUN
bptjm-66	315	16	device	device	NOUN
bptjm-66	315	17	that	that	PRON
bptjm-66	315	18	can	can	AUX
bptjm-66	315	19	be	be	AUX
bptjm-66	315	20	self	self	NOUN
bptjm-66	315	21	-	-	PUNCT
bptjm-66	315	22	administered	administer	VERB
bptjm-66	315	23	,	,	PUNCT
bptjm-66	315	24	with	with	ADP
bptjm-66	315	25	the	the	DET
bptjm-66	315	26	dosage	dosage	NOUN
bptjm-66	315	27	of	of	ADP
bptjm-66	315	28	electrical	electrical	ADJ
bptjm-66	315	29	currents	current	NOUN
bptjm-66	315	30	being	be	AUX
bptjm-66	315	31	delivered	deliver	VERB
bptjm-66	315	32	through	through	ADP
bptjm-66	315	33	electrical	electrical	ADJ
bptjm-66	315	34	pads	pad	NOUN
bptjm-66	315	35	that	that	PRON
bptjm-66	315	36	are	be	AUX
bptjm-66	315	37	attached	attach	VERB
bptjm-66	315	38	to	to	ADP
bptjm-66	315	39	the	the	DET
bptjm-66	315	40	skin	skin	NOUN
bptjm-66	315	41	.	.	PUNCT
bptjm-66	316	1	in	in	ADP
bptjm-66	316	2	addition	addition	NOUN
bptjm-66	316	3	,	,	PUNCT
bptjm-66	316	4	there	there	PRON
bptjm-66	316	5	are	be	VERB
bptjm-66	316	6	three	three	NUM
bptjm-66	316	7	different	different	ADJ
bptjm-66	316	8	techniques	technique	NOUN
bptjm-66	316	9	of	of	ADP
bptjm-66	316	10	tens	ten	NOUN
bptjm-66	316	11	that	that	PRON
bptjm-66	316	12	are	be	AUX
bptjm-66	316	13	used	use	VERB
bptjm-66	316	14	with	with	ADP
bptjm-66	316	15	this	this	DET
bptjm-66	316	16	type	type	NOUN
bptjm-66	316	17	of	of	ADP
bptjm-66	316	18	device	device	NOUN
bptjm-66	316	19	to	to	PART
bptjm-66	316	20	evoke	evoke	VERB
bptjm-66	316	21	different	different	ADJ
bptjm-66	316	22	nerve	nerve	NOUN
bptjm-66	316	23	fibers	fiber	NOUN
bptjm-66	316	24	to	to	PART
bptjm-66	316	25	treat	treat	VERB
bptjm-66	316	26	different	different	ADJ
bptjm-66	316	27	types	type	NOUN
bptjm-66	316	28	of	of	ADP
bptjm-66	316	29	pain	pain	NOUN
bptjm-66	316	30	.	.	PUNCT
bptjm-66	317	1	the	the	DET
bptjm-66	317	2	three	three	NUM
bptjm-66	317	3	different	different	ADJ
bptjm-66	317	4	techniques	technique	NOUN
bptjm-66	317	5	are	be	AUX
bptjm-66	317	6	conventional	conventional	ADJ
bptjm-66	317	7	tens	ten	NOUN
bptjm-66	317	8	,	,	PUNCT
bptjm-66	317	9	acupuncture	acupuncture	NOUN
bptjm-66	317	10	tens	ten	NOUN
bptjm-66	317	11	,	,	PUNCT
bptjm-66	317	12	and	and	CCONJ
bptjm-66	317	13	intense	intense	ADJ
bptjm-66	317	14	tens	ten	NOUN
bptjm-66	317	15	.	.	PUNCT
bptjm-66	318	1	berkeley	berkeley	PROPN
bptjm-66	318	2	pharma	pharma	PROPN
bptjm-66	318	3	tech	tech	PROPN
bptjm-66	318	4	journal	journal	NOUN
bptjm-66	318	5	of	of	ADP
bptjm-66	318	6	medicine	medicine	NOUN
bptjm-66	318	7	|	|	ADV
bptjm-66	318	8	21	21	NUM
bptjm-66	318	9	conventional	conventional	ADJ
bptjm-66	318	10	tens	ten	NOUN
bptjm-66	318	11	is	be	AUX
bptjm-66	318	12	the	the	DET
bptjm-66	318	13	most	most	ADV
bptjm-66	318	14	commonly	commonly	ADV
bptjm-66	318	15	used	use	VERB
bptjm-66	318	16	technique	technique	NOUN
bptjm-66	318	17	and	and	CCONJ
bptjm-66	318	18	is	be	AUX
bptjm-66	318	19	characterized	characterize	VERB
bptjm-66	318	20	by	by	ADP
bptjm-66	318	21	a	a	DET
bptjm-66	318	22	low	low	ADJ
bptjm-66	318	23	-	-	PUNCT
bptjm-66	318	24	intensity	intensity	NOUN
bptjm-66	318	25	and	and	CCONJ
bptjm-66	318	26	high	high	ADJ
bptjm-66	318	27	-	-	PUNCT
bptjm-66	318	28	frequency	frequency	NOUN
bptjm-66	318	29	stimulation54	stimulation54	NOUN
bptjm-66	318	30	.	.	PUNCT
bptjm-66	319	1	the	the	DET
bptjm-66	319	2	overall	overall	ADJ
bptjm-66	319	3	purpose	purpose	NOUN
bptjm-66	319	4	of	of	ADP
bptjm-66	319	5	this	this	DET
bptjm-66	319	6	approach	approach	NOUN
bptjm-66	319	7	is	be	AUX
bptjm-66	319	8	to	to	PART
bptjm-66	319	9	target	target	VERB
bptjm-66	319	10	afferents	afferent	NOUN
bptjm-66	319	11	(	(	PUNCT
bptjm-66	319	12	a	a	DET
bptjm-66	319	13	-	-	PUNCT
bptjm-66	319	14	beta	beta	NOUN
bptjm-66	319	15	fibers	fiber	NOUN
bptjm-66	319	16	)	)	PUNCT
bptjm-66	319	17	that	that	PRON
bptjm-66	319	18	are	be	AUX
bptjm-66	319	19	connected	connect	VERB
bptjm-66	319	20	to	to	ADP
bptjm-66	319	21	the	the	DET
bptjm-66	319	22	central	central	ADJ
bptjm-66	319	23	nervous	nervous	ADJ
bptjm-66	319	24	system	system	NOUN
bptjm-66	319	25	and	and	CCONJ
bptjm-66	319	26	are	be	AUX
bptjm-66	319	27	related	relate	VERB
bptjm-66	319	28	to	to	ADP
bptjm-66	319	29	pain	pain	NOUN
bptjm-66	319	30	.	.	PUNCT
bptjm-66	320	1	conventional	conventional	ADJ
bptjm-66	320	2	tens	ten	NOUN
bptjm-66	320	3	stimulation	stimulation	NOUN
bptjm-66	320	4	affects	affect	VERB
bptjm-66	320	5	a	a	DET
bptjm-66	320	6	broader	broad	ADJ
bptjm-66	320	7	neural	neural	ADJ
bptjm-66	320	8	area	area	NOUN
bptjm-66	320	9	and	and	CCONJ
bptjm-66	320	10	can	can	AUX
bptjm-66	320	11	inhibit	inhibit	VERB
bptjm-66	320	12	nociceptive	nociceptive	ADJ
bptjm-66	320	13	transmission55	transmission55	NOUN
bptjm-66	320	14	.	.	PUNCT
bptjm-66	321	1	acupuncture	acupuncture	NOUN
bptjm-66	321	2	tens	ten	NOUN
bptjm-66	321	3	(	(	PUNCT
bptjm-66	321	4	al	al	PROPN
bptjm-66	321	5	-	-	PUNCT
bptjm-66	321	6	tens	ten	NOUN
bptjm-66	321	7	)	)	PUNCT
bptjm-66	321	8	is	be	AUX
bptjm-66	321	9	considered	consider	VERB
bptjm-66	321	10	a	a	DET
bptjm-66	321	11	high	high	ADJ
bptjm-66	321	12	-	-	PUNCT
bptjm-66	321	13	intensity	intensity	NOUN
bptjm-66	321	14	low	low	ADJ
bptjm-66	321	15	frequency	frequency	NOUN
bptjm-66	321	16	technique	technique	NOUN
bptjm-66	321	17	used	use	VERB
bptjm-66	321	18	for	for	ADP
bptjm-66	321	19	hyperstimulation	hyperstimulation	NOUN
bptjm-66	321	20	.	.	PUNCT
bptjm-66	322	1	al	al	PROPN
bptjm-66	322	2	-	-	PUNCT
bptjm-66	322	3	tens	ten	NOUN
bptjm-66	322	4	targets	target	VERB
bptjm-66	322	5	a	a	DET
bptjm-66	322	6	smaller	small	ADJ
bptjm-66	322	7	area	area	NOUN
bptjm-66	322	8	and	and	CCONJ
bptjm-66	322	9	aims	aim	VERB
bptjm-66	322	10	for	for	ADP
bptjm-66	322	11	higher	high	ADJ
bptjm-66	322	12	threshold	threshold	NOUN
bptjm-66	322	13	peripheral	peripheral	ADJ
bptjm-66	322	14	afferents	afferent	NOUN
bptjm-66	322	15	(	(	PUNCT
bptjm-66	322	16	a	a	DET
bptjm-66	322	17	-	-	PUNCT
bptjm-66	322	18	delta	delta	NOUN
bptjm-66	322	19	)	)	PUNCT
bptjm-66	322	20	.	.	PUNCT
bptjm-66	323	1	during	during	ADP
bptjm-66	323	2	this	this	DET
bptjm-66	323	3	technique	technique	NOUN
bptjm-66	323	4	,	,	PUNCT
bptjm-66	323	5	patients	patient	NOUN
bptjm-66	323	6	may	may	AUX
bptjm-66	323	7	have	have	VERB
bptjm-66	323	8	painless	painless	ADJ
bptjm-66	323	9	muscle	muscle	NOUN
bptjm-66	323	10	twitches	twitch	NOUN
bptjm-66	323	11	because	because	SCONJ
bptjm-66	323	12	of	of	ADP
bptjm-66	323	13	the	the	DET
bptjm-66	323	14	placement	placement	NOUN
bptjm-66	323	15	of	of	ADP
bptjm-66	323	16	the	the	DET
bptjm-66	323	17	electrode	electrode	NOUN
bptjm-66	323	18	pads	pad	NOUN
bptjm-66	323	19	.	.	PUNCT
bptjm-66	324	1	intense	intense	ADJ
bptjm-66	324	2	tens	ten	NOUN
bptjm-66	324	3	is	be	AUX
bptjm-66	324	4	viewed	view	VERB
bptjm-66	324	5	as	as	ADP
bptjm-66	324	6	a	a	DET
bptjm-66	324	7	high	high	ADJ
bptjm-66	324	8	intensity	intensity	NOUN
bptjm-66	324	9	high	high	ADJ
bptjm-66	324	10	frequency	frequency	NOUN
bptjm-66	324	11	technique	technique	NOUN
bptjm-66	324	12	that	that	PRON
bptjm-66	324	13	is	be	AUX
bptjm-66	324	14	used	use	VERB
bptjm-66	324	15	as	as	ADP
bptjm-66	324	16	a	a	DET
bptjm-66	324	17	“	"	PUNCT
bptjm-66	324	18	counter	counter	NOUN
bptjm-66	324	19	-	-	ADJ
bptjm-66	324	20	irritant	irritant	ADJ
bptjm-66	324	21	”	"	PUNCT
bptjm-66	324	22	to	to	PART
bptjm-66	324	23	stop	stop	VERB
bptjm-66	324	24	nociceptive	nociceptive	ADJ
bptjm-66	324	25	transmission	transmission	NOUN
bptjm-66	324	26	in	in	ADP
bptjm-66	324	27	the	the	DET
bptjm-66	324	28	peripheral	peripheral	ADJ
bptjm-66	324	29	nerves	nerve	NOUN
bptjm-66	324	30	before	before	SCONJ
bptjm-66	324	31	it	it	PRON
bptjm-66	324	32	reaches	reach	VERB
bptjm-66	324	33	the	the	DET
bptjm-66	324	34	central	central	ADJ
bptjm-66	324	35	nervous	nervous	ADJ
bptjm-66	324	36	system	system	NOUN
bptjm-66	324	37	.	.	PUNCT
bptjm-66	325	1	this	this	DET
bptjm-66	325	2	technique	technique	NOUN
bptjm-66	325	3	is	be	AUX
bptjm-66	325	4	different	different	ADJ
bptjm-66	325	5	compared	compare	VERB
bptjm-66	325	6	to	to	ADP
bptjm-66	325	7	the	the	DET
bptjm-66	325	8	other	other	ADJ
bptjm-66	325	9	two	two	NUM
bptjm-66	325	10	because	because	SCONJ
bptjm-66	325	11	this	this	DET
bptjm-66	325	12	method	method	NOUN
bptjm-66	325	13	can	can	AUX
bptjm-66	325	14	only	only	ADV
bptjm-66	325	15	be	be	AUX
bptjm-66	325	16	used	use	VERB
bptjm-66	325	17	for	for	ADP
bptjm-66	325	18	a	a	DET
bptjm-66	325	19	small	small	ADJ
bptjm-66	325	20	amount	amount	NOUN
bptjm-66	325	21	of	of	ADP
bptjm-66	325	22	time	time	NOUN
bptjm-66	325	23	compared	compare	VERB
bptjm-66	325	24	to	to	ADP
bptjm-66	325	25	the	the	DET
bptjm-66	325	26	conventional	conventional	ADJ
bptjm-66	325	27	method	method	NOUN
bptjm-66	325	28	,	,	PUNCT
bptjm-66	325	29	which	which	PRON
bptjm-66	325	30	can	can	AUX
bptjm-66	325	31	be	be	AUX
bptjm-66	325	32	used	use	VERB
bptjm-66	325	33	as	as	ADV
bptjm-66	325	34	long	long	ADV
bptjm-66	325	35	as	as	ADP
bptjm-66	325	36	the	the	DET
bptjm-66	325	37	patient	patient	ADJ
bptjm-66	325	38	desires	desire	NOUN
bptjm-66	325	39	.	.	PUNCT
bptjm-66	326	1	the	the	DET
bptjm-66	326	2	overall	overall	ADJ
bptjm-66	326	3	method	method	NOUN
bptjm-66	326	4	of	of	ADP
bptjm-66	326	5	tens	ten	NOUN
bptjm-66	326	6	affects	affect	VERB
bptjm-66	326	7	the	the	DET
bptjm-66	326	8	surrounding	surround	VERB
bptjm-66	326	9	area	area	NOUN
bptjm-66	326	10	by	by	ADP
bptjm-66	326	11	reducing	reduce	VERB
bptjm-66	326	12	the	the	DET
bptjm-66	326	13	transmission	transmission	NOUN
bptjm-66	326	14	of	of	ADP
bptjm-66	326	15	nociceptive	nociceptive	ADJ
bptjm-66	326	16	neurons	neuron	NOUN
bptjm-66	326	17	.	.	PUNCT
bptjm-66	327	1	tens	ten	NOUN
bptjm-66	327	2	can	can	AUX
bptjm-66	327	3	also	also	ADV
bptjm-66	327	4	activate	activate	VERB
bptjm-66	327	5	extra	extra	ADJ
bptjm-66	327	6	-	-	ADJ
bptjm-66	327	7	segmental	segmental	ADJ
bptjm-66	327	8	areas	area	NOUN
bptjm-66	327	9	including	include	VERB
bptjm-66	327	10	the	the	DET
bptjm-66	327	11	midbrain	midbrain	NOUN
bptjm-66	327	12	and	and	CCONJ
bptjm-66	327	13	the	the	DET
bptjm-66	327	14	medulla	medulla	NOUN
bptjm-66	327	15	.	.	PUNCT
bptjm-66	328	1	the	the	DET
bptjm-66	328	2	activation	activation	NOUN
bptjm-66	328	3	in	in	ADP
bptjm-66	328	4	the	the	DET
bptjm-66	328	5	midbrain	midbrain	NOUN
bptjm-66	328	6	and	and	CCONJ
bptjm-66	328	7	medulla	medulla	NOUN
bptjm-66	328	8	complexes	complex	NOUN
bptjm-66	328	9	then	then	ADV
bptjm-66	328	10	triggers	trigger	VERB
bptjm-66	328	11	descending	descend	VERB
bptjm-66	328	12	inhibitory	inhibitory	ADJ
bptjm-66	328	13	systems	system	NOUN
bptjm-66	328	14	which	which	PRON
bptjm-66	328	15	reduces	reduce	VERB
bptjm-66	328	16	hyperalgesia	hyperalgesia	NOUN
bptjm-66	328	17	,	,	PUNCT
bptjm-66	328	18	an	an	DET
bptjm-66	328	19	increased	increase	VERB
bptjm-66	328	20	sensitivity	sensitivity	NOUN
bptjm-66	328	21	to	to	AUX
bptjm-66	328	22	pain	pain	NOUN
bptjm-66	328	23	,	,	PUNCT
bptjm-66	328	24	or	or	CCONJ
bptjm-66	328	25	an	an	DET
bptjm-66	328	26	extreme	extreme	ADJ
bptjm-66	328	27	response	response	NOUN
bptjm-66	328	28	to	to	ADP
bptjm-66	328	29	pain	pain	NOUN
bptjm-66	328	30	.	.	PUNCT
bptjm-66	329	1	although	although	SCONJ
bptjm-66	329	2	the	the	DET
bptjm-66	329	3	main	main	ADJ
bptjm-66	329	4	intent	intent	NOUN
bptjm-66	329	5	of	of	ADP
bptjm-66	329	6	tens	ten	NOUN
bptjm-66	329	7	is	be	AUX
bptjm-66	329	8	through	through	ADP
bptjm-66	329	9	electrical	electrical	ADJ
bptjm-66	329	10	stimulation	stimulation	NOUN
bptjm-66	329	11	,	,	PUNCT
bptjm-66	329	12	some	some	DET
bptjm-66	329	13	neurochemicals	neurochemical	NOUN
bptjm-66	329	14	help	help	VERB
bptjm-66	329	15	further	far	ADV
bptjm-66	329	16	the	the	DET
bptjm-66	329	17	effects	effect	NOUN
bptjm-66	329	18	of	of	ADP
bptjm-66	329	19	tens	ten	NOUN
bptjm-66	329	20	.	.	PUNCT
bptjm-66	330	1	low	low	ADJ
bptjm-66	330	2	frequency	frequency	NOUN
bptjm-66	330	3	stimulation	stimulation	NOUN
bptjm-66	330	4	has	have	AUX
bptjm-66	330	5	demonstrated	demonstrate	VERB
bptjm-66	330	6	the	the	DET
bptjm-66	330	7	involvement	involvement	NOUN
bptjm-66	330	8	of	of	ADP
bptjm-66	330	9	the	the	DET
bptjm-66	330	10	mu	mu	NOUN
bptjm-66	330	11	opioid	opioid	ADJ
bptjm-66	330	12	receptor	receptor	NOUN
bptjm-66	330	13	and	and	CCONJ
bptjm-66	330	14	high	high	ADJ
bptjm-66	330	15	frequency	frequency	NOUN
bptjm-66	330	16	has	have	AUX
bptjm-66	330	17	displayed	display	VERB
bptjm-66	330	18	the	the	DET
bptjm-66	330	19	use	use	NOUN
bptjm-66	330	20	of	of	ADP
bptjm-66	330	21	the	the	DET
bptjm-66	330	22	delta	delta	NOUN
bptjm-66	330	23	opioid	opioid	ADJ
bptjm-66	330	24	receptors	receptor	NOUN
bptjm-66	330	25	.	.	PUNCT
bptjm-66	331	1	tens	ten	NOUN
bptjm-66	331	2	is	be	AUX
bptjm-66	331	3	still	still	ADV
bptjm-66	331	4	being	be	AUX
bptjm-66	331	5	researched	research	VERB
bptjm-66	331	6	and	and	CCONJ
bptjm-66	331	7	garnering	garner	VERB
bptjm-66	331	8	more	more	ADJ
bptjm-66	331	9	information	information	NOUN
bptjm-66	331	10	but	but	CCONJ
bptjm-66	331	11	has	have	AUX
bptjm-66	331	12	shown	show	VERB
bptjm-66	331	13	promising	promising	ADJ
bptjm-66	331	14	results	result	NOUN
bptjm-66	331	15	in	in	ADP
bptjm-66	331	16	multiple	multiple	ADJ
bptjm-66	331	17	clinical	clinical	ADJ
bptjm-66	331	18	trials	trial	NOUN
bptjm-66	331	19	.	.	PUNCT
bptjm-66	332	1	berkeley	berkeley	PROPN
bptjm-66	332	2	pharma	pharma	PROPN
bptjm-66	332	3	tech	tech	PROPN
bptjm-66	332	4	journal	journal	NOUN
bptjm-66	332	5	of	of	ADP
bptjm-66	332	6	medicine	medicine	NOUN
bptjm-66	332	7	|	|	ADV
bptjm-66	332	8	22	22	NUM
bptjm-66	332	9	figure	figure	NOUN
bptjm-66	332	10	6	6	NUM
bptjm-66	332	11	.	.	PUNCT
bptjm-66	332	12	common	common	ADJ
bptjm-66	332	13	tens	ten	NOUN
bptjm-66	332	14	device	device	NOUN
bptjm-66	332	15	a	a	DET
bptjm-66	332	16	heat	heat	NOUN
bptjm-66	332	17	application	application	NOUN
bptjm-66	332	18	studied	study	VERB
bptjm-66	332	19	in	in	ADP
bptjm-66	332	20	clinical	clinical	ADJ
bptjm-66	332	21	trials	trial	NOUN
bptjm-66	332	22	garnered	garner	VERB
bptjm-66	332	23	positive	positive	ADJ
bptjm-66	332	24	effects56	effects56	NOUN
bptjm-66	332	25	.	.	PUNCT
bptjm-66	333	1	when	when	SCONJ
bptjm-66	333	2	applying	apply	VERB
bptjm-66	333	3	tens	ten	NOUN
bptjm-66	333	4	and	and	CCONJ
bptjm-66	333	5	heat	heat	NOUN
bptjm-66	333	6	stimulation	stimulation	NOUN
bptjm-66	333	7	in	in	ADP
bptjm-66	333	8	a	a	DET
bptjm-66	333	9	2021	2021	NUM
bptjm-66	333	10	clinical	clinical	ADJ
bptjm-66	333	11	trial	trial	NOUN
bptjm-66	333	12	,	,	PUNCT
bptjm-66	333	13	the	the	DET
bptjm-66	333	14	results	result	NOUN
bptjm-66	333	15	showed	show	VERB
bptjm-66	333	16	a	a	DET
bptjm-66	333	17	significant	significant	ADJ
bptjm-66	333	18	improvement	improvement	NOUN
bptjm-66	333	19	in	in	ADP
bptjm-66	333	20	average	average	ADJ
bptjm-66	333	21	pain	pain	NOUN
bptjm-66	333	22	experienced	experience	VERB
bptjm-66	333	23	by	by	ADP
bptjm-66	333	24	those	those	PRON
bptjm-66	333	25	affected	affect	VERB
bptjm-66	333	26	by	by	ADP
bptjm-66	333	27	chronic	chronic	NOUN
bptjm-66	333	28	lower	low	ADJ
bptjm-66	333	29	back	back	ADJ
bptjm-66	333	30	pain	pain	NOUN
bptjm-66	333	31	.	.	PUNCT
bptjm-66	334	1	the	the	DET
bptjm-66	334	2	clinical	clinical	ADJ
bptjm-66	334	3	trial	trial	NOUN
bptjm-66	334	4	was	be	AUX
bptjm-66	334	5	a	a	DET
bptjm-66	334	6	randomized	randomized	ADJ
bptjm-66	334	7	,	,	PUNCT
bptjm-66	334	8	double	double	ADJ
bptjm-66	334	9	-	-	PUNCT
bptjm-66	334	10	blinded	blind	VERB
bptjm-66	334	11	controlled	control	VERB
bptjm-66	334	12	trial	trial	NOUN
bptjm-66	334	13	to	to	PART
bptjm-66	334	14	test	test	VERB
bptjm-66	334	15	the	the	DET
bptjm-66	334	16	early	early	ADJ
bptjm-66	334	17	intervention	intervention	NOUN
bptjm-66	334	18	of	of	ADP
bptjm-66	334	19	tens	ten	NOUN
bptjm-66	334	20	for	for	ADP
bptjm-66	334	21	a	a	DET
bptjm-66	334	22	spinal	spinal	ADJ
bptjm-66	334	23	injury	injury	NOUN
bptjm-66	334	24	.	.	PUNCT
bptjm-66	335	1	a	a	DET
bptjm-66	335	2	treatment	treatment	NOUN
bptjm-66	335	3	of	of	ADP
bptjm-66	335	4	30	30	NUM
bptjm-66	335	5	minutes	minute	NOUN
bptjm-66	335	6	of	of	ADP
bptjm-66	335	7	tens	ten	NOUN
bptjm-66	335	8	therapy	therapy	NOUN
bptjm-66	335	9	twice	twice	DET
bptjm-66	335	10	a	a	DET
bptjm-66	335	11	week	week	NOUN
bptjm-66	335	12	for	for	ADP
bptjm-66	335	13	8	8	NUM
bptjm-66	335	14	weeks	week	NOUN
bptjm-66	335	15	or	or	CCONJ
bptjm-66	335	16	a	a	DET
bptjm-66	335	17	sham	sham	ADJ
bptjm-66	335	18	tens	ten	NOUN
bptjm-66	335	19	therapy	therapy	NOUN
bptjm-66	335	20	was	be	AUX
bptjm-66	335	21	supplied	supply	VERB
bptjm-66	335	22	as	as	ADP
bptjm-66	335	23	a	a	DET
bptjm-66	335	24	placebo	placebo	NOUN
bptjm-66	335	25	(	(	PUNCT
bptjm-66	335	26	n=26	n=26	PROPN
bptjm-66	335	27	)	)	PUNCT
bptjm-66	335	28	.	.	PUNCT
bptjm-66	336	1	there	there	PRON
bptjm-66	336	2	were	be	VERB
bptjm-66	336	3	4	4	NUM
bptjm-66	336	4	pads	pad	NOUN
bptjm-66	336	5	applied	apply	VERB
bptjm-66	336	6	,	,	PUNCT
bptjm-66	336	7	2	2	NUM
bptjm-66	336	8	located	locate	VERB
bptjm-66	336	9	paraspinally	paraspinally	ADV
bptjm-66	336	10	to	to	ADP
bptjm-66	336	11	the	the	DET
bptjm-66	336	12	spinal	spinal	ADJ
bptjm-66	336	13	injury	injury	NOUN
bptjm-66	336	14	and	and	CCONJ
bptjm-66	336	15	the	the	DET
bptjm-66	336	16	other	other	ADJ
bptjm-66	336	17	2	2	NUM
bptjm-66	336	18	located	locate	VERB
bptjm-66	336	19	ventrally	ventrally	ADV
bptjm-66	336	20	within	within	ADP
bptjm-66	336	21	the	the	DET
bptjm-66	336	22	dermatome	dermatome	NOUN
bptjm-66	336	23	of	of	ADP
bptjm-66	336	24	the	the	DET
bptjm-66	336	25	injury	injury	NOUN
bptjm-66	336	26	.	.	PUNCT
bptjm-66	337	1	the	the	DET
bptjm-66	337	2	overall	overall	ADJ
bptjm-66	337	3	end	end	NOUN
bptjm-66	337	4	showed	show	VERB
bptjm-66	337	5	one	one	NUM
bptjm-66	337	6	patient	patient	NOUN
bptjm-66	337	7	from	from	ADP
bptjm-66	337	8	the	the	DET
bptjm-66	337	9	tens	ten	NOUN
bptjm-66	337	10	treatment	treatment	NOUN
bptjm-66	337	11	and	and	CCONJ
bptjm-66	337	12	2	2	NUM
bptjm-66	337	13	from	from	ADP
bptjm-66	337	14	the	the	DET
bptjm-66	337	15	sham	sham	ADJ
bptjm-66	337	16	treatment	treatment	NOUN
bptjm-66	337	17	having	have	VERB
bptjm-66	337	18	adverse	adverse	ADJ
bptjm-66	337	19	reactions	reaction	NOUN
bptjm-66	337	20	related	relate	VERB
bptjm-66	337	21	to	to	ADP
bptjm-66	337	22	the	the	DET
bptjm-66	337	23	study	study	NOUN
bptjm-66	337	24	.	.	PUNCT
bptjm-66	338	1	with	with	ADP
bptjm-66	338	2	many	many	ADJ
bptjm-66	338	3	clinical	clinical	ADJ
bptjm-66	338	4	trials	trial	NOUN
bptjm-66	338	5	showing	show	VERB
bptjm-66	338	6	promising	promising	ADJ
bptjm-66	338	7	results	result	NOUN
bptjm-66	338	8	,	,	PUNCT
bptjm-66	338	9	they	they	PRON
bptjm-66	338	10	have	have	AUX
bptjm-66	338	11	also	also	ADV
bptjm-66	338	12	shown	show	VERB
bptjm-66	338	13	some	some	DET
bptjm-66	338	14	complications	complication	NOUN
bptjm-66	338	15	with	with	ADP
bptjm-66	338	16	interactions	interaction	NOUN
bptjm-66	338	17	with	with	ADP
bptjm-66	338	18	pre	pre	ADJ
bptjm-66	338	19	-	-	ADJ
bptjm-66	338	20	dispositioned	dispositioned	ADJ
bptjm-66	338	21	illness	illness	NOUN
bptjm-66	338	22	.	.	PUNCT
bptjm-66	339	1	people	people	NOUN
bptjm-66	339	2	with	with	ADP
bptjm-66	339	3	epilepsy	epilepsy	NOUN
bptjm-66	339	4	,	,	PUNCT
bptjm-66	339	5	who	who	PRON
bptjm-66	339	6	are	be	AUX
bptjm-66	339	7	pregnant	pregnant	ADJ
bptjm-66	339	8	or	or	CCONJ
bptjm-66	339	9	have	have	VERB
bptjm-66	339	10	a	a	DET
bptjm-66	339	11	pacemaker	pacemaker	NOUN
bptjm-66	339	12	have	have	AUX
bptjm-66	339	13	been	be	AUX
bptjm-66	339	14	shown	show	VERB
bptjm-66	339	15	to	to	PART
bptjm-66	339	16	have	have	VERB
bptjm-66	339	17	more	more	ADJ
bptjm-66	339	18	risk	risk	NOUN
bptjm-66	339	19	of	of	ADP
bptjm-66	339	20	complications	complication	NOUN
bptjm-66	339	21	.	.	PUNCT
bptjm-66	340	1	in	in	ADP
bptjm-66	340	2	addition	addition	NOUN
bptjm-66	340	3	,	,	PUNCT
bptjm-66	340	4	there	there	PRON
bptjm-66	340	5	have	have	AUX
bptjm-66	340	6	been	be	AUX
bptjm-66	340	7	negative	negative	ADJ
bptjm-66	340	8	effects	effect	NOUN
bptjm-66	340	9	due	due	ADJ
bptjm-66	340	10	to	to	ADP
bptjm-66	340	11	inappropriate	inappropriate	ADJ
bptjm-66	340	12	positioning	positioning	NOUN
bptjm-66	340	13	of	of	ADP
bptjm-66	340	14	the	the	DET
bptjm-66	340	15	electrode	electrode	NOUN
bptjm-66	340	16	pads	pad	NOUN
bptjm-66	340	17	.	.	PUNCT
bptjm-66	341	1	current	current	ADJ
bptjm-66	341	2	common	common	ADJ
bptjm-66	341	3	errors	error	NOUN
bptjm-66	341	4	in	in	ADP
bptjm-66	341	5	placement	placement	NOUN
bptjm-66	341	6	of	of	ADP
bptjm-66	341	7	the	the	DET
bptjm-66	341	8	pads	pad	NOUN
bptjm-66	341	9	include	include	VERB
bptjm-66	341	10	over	over	ADP
bptjm-66	341	11	the	the	DET
bptjm-66	341	12	chest	chest	NOUN
bptjm-66	341	13	near	near	ADP
bptjm-66	341	14	the	the	DET
bptjm-66	341	15	heart	heart	NOUN
bptjm-66	341	16	,	,	PUNCT
bptjm-66	341	17	eyes	eye	NOUN
bptjm-66	341	18	,	,	PUNCT
bptjm-66	341	19	and	and	CCONJ
bptjm-66	341	20	internally	internally	ADV
bptjm-66	341	21	unless	unless	SCONJ
bptjm-66	341	22	specified	specify	VERB
bptjm-66	341	23	for	for	ADP
bptjm-66	341	24	internal	internal	ADJ
bptjm-66	341	25	use	use	NOUN
bptjm-66	341	26	.	.	PUNCT
bptjm-66	342	1	overall	overall	ADJ
bptjm-66	342	2	the	the	DET
bptjm-66	342	3	use	use	NOUN
bptjm-66	342	4	of	of	ADP
bptjm-66	342	5	berkeley	berkeley	PROPN
bptjm-66	342	6	pharma	pharma	PROPN
bptjm-66	342	7	tech	tech	NOUN
bptjm-66	342	8	journal	journal	NOUN
bptjm-66	342	9	of	of	ADP
bptjm-66	342	10	medicine	medicine	NOUN
bptjm-66	342	11	|	|	ADV
bptjm-66	342	12	23	23	NUM
bptjm-66	342	13	tens	ten	NOUN
bptjm-66	342	14	has	have	AUX
bptjm-66	342	15	been	be	AUX
bptjm-66	342	16	shown	show	VERB
bptjm-66	342	17	to	to	PART
bptjm-66	342	18	be	be	AUX
bptjm-66	342	19	safe	safe	ADJ
bptjm-66	342	20	with	with	ADP
bptjm-66	342	21	little	little	ADJ
bptjm-66	342	22	to	to	ADP
bptjm-66	342	23	no	no	DET
bptjm-66	342	24	side	side	NOUN
bptjm-66	342	25	effects	effect	NOUN
bptjm-66	342	26	for	for	ADP
bptjm-66	342	27	most	most	ADJ
bptjm-66	342	28	people	people	NOUN
bptjm-66	342	29	.	.	PUNCT
bptjm-66	343	1	4.3	4.3	NUM
bptjm-66	343	2	photobiomodulation	photobiomodulation	NOUN
bptjm-66	343	3	photobiomodulation	photobiomodulation	NOUN
bptjm-66	343	4	is	be	AUX
bptjm-66	343	5	an	an	DET
bptjm-66	343	6	external	external	ADJ
bptjm-66	343	7	treatment	treatment	NOUN
bptjm-66	343	8	that	that	PRON
bptjm-66	343	9	uses	use	VERB
bptjm-66	343	10	laser	laser	NOUN
bptjm-66	343	11	and	and	CCONJ
bptjm-66	343	12	led	lead	VERB
bptjm-66	343	13	light	light	NOUN
bptjm-66	343	14	to	to	PART
bptjm-66	343	15	affect	affect	VERB
bptjm-66	343	16	the	the	DET
bptjm-66	343	17	action	action	NOUN
bptjm-66	343	18	potentials	potential	NOUN
bptjm-66	343	19	of	of	ADP
bptjm-66	343	20	the	the	DET
bptjm-66	343	21	pain	pain	NOUN
bptjm-66	343	22	pathway	pathway	NOUN
bptjm-66	343	23	.	.	PUNCT
bptjm-66	344	1	the	the	DET
bptjm-66	344	2	method	method	NOUN
bptjm-66	344	3	uses	use	VERB
bptjm-66	344	4	low	low	ADJ
bptjm-66	344	5	-	-	PUNCT
bptjm-66	344	6	intensity	intensity	NOUN
bptjm-66	344	7	red	red	ADJ
bptjm-66	344	8	or	or	CCONJ
bptjm-66	344	9	near	near	ADV
bptjm-66	344	10	-	-	PUNCT
bptjm-66	344	11	infrared	infrared	ADJ
bptjm-66	344	12	light	light	NOUN
bptjm-66	344	13	that	that	PRON
bptjm-66	344	14	is	be	AUX
bptjm-66	344	15	brought	bring	VERB
bptjm-66	344	16	near	near	ADP
bptjm-66	344	17	the	the	DET
bptjm-66	344	18	surface	surface	NOUN
bptjm-66	344	19	of	of	ADP
bptjm-66	344	20	the	the	DET
bptjm-66	344	21	skin	skin	NOUN
bptjm-66	344	22	,	,	PUNCT
bptjm-66	344	23	relative	relative	ADJ
bptjm-66	344	24	to	to	ADP
bptjm-66	344	25	other	other	ADJ
bptjm-66	344	26	energy	energy	NOUN
bptjm-66	344	27	densities	density	NOUN
bptjm-66	344	28	in	in	ADP
bptjm-66	344	29	laser	laser	NOUN
bptjm-66	344	30	therapy	therapy	NOUN
bptjm-66	344	31	used	use	VERB
bptjm-66	344	32	for	for	ADP
bptjm-66	344	33	ablation	ablation	NOUN
bptjm-66	344	34	,	,	PUNCT
bptjm-66	344	35	cutting	cutting	NOUN
bptjm-66	344	36	,	,	PUNCT
bptjm-66	344	37	and	and	CCONJ
bptjm-66	344	38	the	the	DET
bptjm-66	344	39	thermal	thermal	ADJ
bptjm-66	344	40	coagulation	coagulation	NOUN
bptjm-66	344	41	of	of	ADP
bptjm-66	344	42	tissue57	tissue57	NOUN
bptjm-66	344	43	.	.	PUNCT
bptjm-66	345	1	it	it	PRON
bptjm-66	345	2	interferes	interfere	VERB
bptjm-66	345	3	with	with	ADP
bptjm-66	345	4	the	the	DET
bptjm-66	345	5	stimulation	stimulation	NOUN
bptjm-66	345	6	of	of	ADP
bptjm-66	345	7	action	action	NOUN
bptjm-66	345	8	potentials	potential	VERB
bptjm-66	345	9	within	within	ADP
bptjm-66	345	10	the	the	DET
bptjm-66	345	11	mitochondria	mitochondria	NOUN
bptjm-66	345	12	by	by	ADP
bptjm-66	345	13	initially	initially	ADV
bptjm-66	345	14	interacting	interact	VERB
bptjm-66	345	15	with	with	ADP
bptjm-66	345	16	the	the	DET
bptjm-66	345	17	peripheral	peripheral	ADJ
bptjm-66	345	18	nerves	nerve	NOUN
bptjm-66	345	19	and	and	CCONJ
bptjm-66	345	20	having	have	VERB
bptjm-66	345	21	the	the	DET
bptjm-66	345	22	electrons	electron	NOUN
bptjm-66	345	23	join	join	VERB
bptjm-66	345	24	part	part	NOUN
bptjm-66	345	25	of	of	ADP
bptjm-66	345	26	the	the	DET
bptjm-66	345	27	photoreceptor	photoreceptor	NOUN
bptjm-66	345	28	on	on	ADP
bptjm-66	345	29	the	the	DET
bptjm-66	345	30	skin	skin	NOUN
bptjm-66	345	31	.	.	PUNCT
bptjm-66	346	1	these	these	DET
bptjm-66	346	2	photoreceptors	photoreceptor	NOUN
bptjm-66	346	3	stimulate	stimulate	VERB
bptjm-66	346	4	membrane	membrane	NOUN
bptjm-66	346	5	potential	potential	NOUN
bptjm-66	346	6	and	and	CCONJ
bptjm-66	346	7	cause	cause	VERB
bptjm-66	346	8	extra	extra	ADJ
bptjm-66	346	9	absorption	absorption	NOUN
bptjm-66	346	10	into	into	ADP
bptjm-66	346	11	the	the	DET
bptjm-66	346	12	potassium	potassium	NOUN
bptjm-66	346	13	and	and	CCONJ
bptjm-66	346	14	sodium	sodium	NOUN
bptjm-66	346	15	channels	channel	NOUN
bptjm-66	346	16	.	.	PUNCT
bptjm-66	347	1	this	this	PRON
bptjm-66	347	2	increases	increase	VERB
bptjm-66	347	3	the	the	DET
bptjm-66	347	4	reabsorption	reabsorption	NOUN
bptjm-66	347	5	power	power	NOUN
bptjm-66	347	6	of	of	ADP
bptjm-66	347	7	sodium	sodium	NOUN
bptjm-66	347	8	and	and	CCONJ
bptjm-66	347	9	potassium	potassium	NOUN
bptjm-66	347	10	which	which	PRON
bptjm-66	347	11	keeps	keep	VERB
bptjm-66	347	12	the	the	DET
bptjm-66	347	13	action	action	NOUN
bptjm-66	347	14	potential	potential	NOUN
bptjm-66	347	15	from	from	ADP
bptjm-66	347	16	crossing	cross	VERB
bptjm-66	347	17	the	the	DET
bptjm-66	347	18	threshold	threshold	NOUN
bptjm-66	347	19	needed	need	VERB
bptjm-66	347	20	.	.	PUNCT
bptjm-66	348	1	the	the	DET
bptjm-66	348	2	electron	electron	NOUN
bptjm-66	348	3	transfer	transfer	NOUN
bptjm-66	348	4	by	by	ADP
bptjm-66	348	5	photons	photon	NOUN
bptjm-66	348	6	in	in	ADP
bptjm-66	348	7	the	the	DET
bptjm-66	348	8	visible	visible	ADJ
bptjm-66	348	9	and	and	CCONJ
bptjm-66	348	10	near	near	ADV
bptjm-66	348	11	-	-	PUNCT
bptjm-66	348	12	infrared	infrare	VERB
bptjm-66	348	13	light	light	NOUN
bptjm-66	348	14	spectrum	spectrum	VERB
bptjm-66	348	15	through	through	ADP
bptjm-66	348	16	the	the	DET
bptjm-66	348	17	modulation	modulation	NOUN
bptjm-66	348	18	of	of	ADP
bptjm-66	348	19	cytochrome	cytochrome	ADJ
bptjm-66	348	20	c	c	NOUN
bptjm-66	348	21	-	-	PUNCT
bptjm-66	348	22	oxidase	oxidase	NOUN
bptjm-66	348	23	activity	activity	NOUN
bptjm-66	348	24	,	,	PUNCT
bptjm-66	348	25	increasing	increase	VERB
bptjm-66	348	26	atp	atp	NOUN
bptjm-66	348	27	production	production	NOUN
bptjm-66	348	28	,	,	PUNCT
bptjm-66	348	29	modulation	modulation	NOUN
bptjm-66	348	30	of	of	ADP
bptjm-66	348	31	redox	redox	ADJ
bptjm-66	348	32	states	state	NOUN
bptjm-66	348	33	,	,	PUNCT
bptjm-66	348	34	and	and	CCONJ
bptjm-66	348	35	inducing	induce	VERB
bptjm-66	348	36	transcription	transcription	NOUN
bptjm-66	348	37	factors58	factors58	ADJ
bptjm-66	348	38	.	.	PUNCT
bptjm-66	349	1	due	due	ADP
bptjm-66	349	2	to	to	ADP
bptjm-66	349	3	limited	limited	ADJ
bptjm-66	349	4	understanding	understanding	NOUN
bptjm-66	349	5	of	of	ADP
bptjm-66	349	6	its	its	PRON
bptjm-66	349	7	effects	effect	NOUN
bptjm-66	349	8	on	on	ADP
bptjm-66	349	9	the	the	DET
bptjm-66	349	10	molecular	molecular	ADJ
bptjm-66	349	11	,	,	PUNCT
bptjm-66	349	12	cellular	cellular	ADJ
bptjm-66	349	13	,	,	PUNCT
bptjm-66	349	14	and	and	CCONJ
bptjm-66	349	15	tissular	tissular	ADJ
bptjm-66	349	16	mechanisms	mechanism	NOUN
bptjm-66	349	17	,	,	PUNCT
bptjm-66	349	18	photobiomodulation	photobiomodulation	NOUN
bptjm-66	349	19	has	have	AUX
bptjm-66	349	20	not	not	PART
bptjm-66	349	21	been	be	AUX
bptjm-66	349	22	widely	widely	ADV
bptjm-66	349	23	accepted	accept	VERB
bptjm-66	349	24	in	in	ADP
bptjm-66	349	25	clinical	clinical	ADJ
bptjm-66	349	26	settings	setting	NOUN
bptjm-66	349	27	.	.	PUNCT
bptjm-66	350	1	in	in	ADP
bptjm-66	350	2	recent	recent	ADJ
bptjm-66	350	3	years	year	NOUN
bptjm-66	350	4	,	,	PUNCT
bptjm-66	350	5	the	the	DET
bptjm-66	350	6	effects	effect	NOUN
bptjm-66	350	7	of	of	ADP
bptjm-66	350	8	photobiomodulation	photobiomodulation	NOUN
bptjm-66	350	9	have	have	AUX
bptjm-66	350	10	been	be	AUX
bptjm-66	350	11	further	further	ADJ
bptjm-66	350	12	studied59	studied59	X
bptjm-66	350	13	.	.	PUNCT
bptjm-66	351	1	figure	figure	VERB
bptjm-66	351	2	7	7	NUM
bptjm-66	351	3	.	.	PUNCT
bptjm-66	351	4	photobiomodulation	photobiomodulation	NOUN
bptjm-66	351	5	mechanism	mechanism	NOUN
bptjm-66	351	6	of	of	ADP
bptjm-66	351	7	action	action	NOUN
bptjm-66	351	8	a	a	DET
bptjm-66	351	9	double	double	ADV
bptjm-66	351	10	-	-	PUNCT
bptjm-66	351	11	armed	arm	VERB
bptjm-66	351	12	,	,	PUNCT
bptjm-66	351	13	randomized	randomize	VERB
bptjm-66	351	14	,	,	PUNCT
bptjm-66	351	15	sham	sham	PROPN
bptjm-66	351	16	-	-	PUNCT
bptjm-66	351	17	controlled	control	VERB
bptjm-66	351	18	,	,	PUNCT
bptjm-66	351	19	double	double	ADJ
bptjm-66	351	20	-	-	PUNCT
bptjm-66	351	21	blinded	blind	VERB
bptjm-66	351	22	clinical	clinical	ADJ
bptjm-66	351	23	trial	trial	NOUN
bptjm-66	351	24	of	of	ADP
bptjm-66	351	25	photobiomodulation	photobiomodulation	NOUN
bptjm-66	351	26	therapy	therapy	NOUN
bptjm-66	351	27	with	with	ADP
bptjm-66	351	28	a	a	DET
bptjm-66	351	29	3:4	3:4	NUM
bptjm-66	351	30	ratio	ratio	NOUN
bptjm-66	351	31	(	(	PUNCT
bptjm-66	351	32	n=70	n=70	PROPN
bptjm-66	351	33	)	)	PUNCT
bptjm-66	351	34	to	to	ADP
bptjm-66	351	35	treatment	treatment	NOUN
bptjm-66	351	36	or	or	CCONJ
bptjm-66	351	37	berkeley	berkeley	PROPN
bptjm-66	351	38	pharma	pharma	PROPN
bptjm-66	351	39	tech	tech	NOUN
bptjm-66	351	40	journal	journal	NOUN
bptjm-66	351	41	of	of	ADP
bptjm-66	351	42	medicine	medicine	NOUN
bptjm-66	351	43	|	|	ADV
bptjm-66	351	44	24	24	NUM
bptjm-66	351	45	sham	sham	ADJ
bptjm-66	351	46	arms	arm	NOUN
bptjm-66	351	47	was	be	AUX
bptjm-66	351	48	conducive	conducive	ADJ
bptjm-66	351	49	to	to	ADP
bptjm-66	351	50	less	less	ADV
bptjm-66	351	51	neuropathic	neuropathic	ADJ
bptjm-66	351	52	pain	pain	NOUN
bptjm-66	351	53	in	in	ADP
bptjm-66	351	54	treating	treat	VERB
bptjm-66	351	55	chemotherapy	chemotherapy	NOUN
bptjm-66	351	56	-	-	PUNCT
bptjm-66	351	57	associated	associate	VERB
bptjm-66	351	58	peripheral	peripheral	ADJ
bptjm-66	351	59	neuropathy	neuropathy	ADJ
bptjm-66	351	60	.	.	PUNCT
bptjm-66	352	1	each	each	DET
bptjm-66	352	2	patient	patient	NOUN
bptjm-66	352	3	was	be	AUX
bptjm-66	352	4	given	give	VERB
bptjm-66	352	5	18	18	NUM
bptjm-66	352	6	treatments	treatment	NOUN
bptjm-66	352	7	of	of	ADP
bptjm-66	352	8	30	30	NUM
bptjm-66	352	9	-	-	PUNCT
bptjm-66	352	10	minute	minute	NOUN
bptjm-66	352	11	duration	duration	NOUN
bptjm-66	352	12	three	three	NUM
bptjm-66	352	13	times	time	NOUN
bptjm-66	352	14	a	a	DET
bptjm-66	352	15	week	week	NOUN
bptjm-66	352	16	,	,	PUNCT
bptjm-66	352	17	which	which	PRON
bptjm-66	352	18	included	include	VERB
bptjm-66	352	19	laser	laser	NOUN
bptjm-66	352	20	exposure	exposure	NOUN
bptjm-66	352	21	to	to	ADP
bptjm-66	352	22	areas	area	NOUN
bptjm-66	352	23	of	of	ADP
bptjm-66	352	24	pain	pain	NOUN
bptjm-66	352	25	which	which	PRON
bptjm-66	352	26	included	include	VERB
bptjm-66	352	27	the	the	DET
bptjm-66	352	28	legs	leg	NOUN
bptjm-66	352	29	,	,	PUNCT
bptjm-66	352	30	feet	foot	NOUN
bptjm-66	352	31	,	,	PUNCT
bptjm-66	352	32	cervical	cervical	ADJ
bptjm-66	352	33	spine	spine	ADJ
bptjm-66	352	34	region	region	NOUN
bptjm-66	352	35	,	,	PUNCT
bptjm-66	352	36	and	and	CCONJ
bptjm-66	352	37	lumbar	lumbar	NOUN
bptjm-66	352	38	spine	spine	ADJ
bptjm-66	352	39	region	region	NOUN
bptjm-66	352	40	for	for	ADP
bptjm-66	352	41	anywhere	anywhere	ADV
bptjm-66	352	42	between	between	ADP
bptjm-66	352	43	3	3	NUM
bptjm-66	352	44	to	to	PART
bptjm-66	352	45	30	30	NUM
bptjm-66	352	46	minutes	minute	NOUN
bptjm-66	352	47	,	,	PUNCT
bptjm-66	352	48	based	base	VERB
bptjm-66	352	49	on	on	ADP
bptjm-66	352	50	the	the	DET
bptjm-66	352	51	severity	severity	NOUN
bptjm-66	352	52	of	of	ADP
bptjm-66	352	53	the	the	DET
bptjm-66	352	54	symptoms	symptom	NOUN
bptjm-66	352	55	.	.	PUNCT
bptjm-66	353	1	the	the	DET
bptjm-66	353	2	change	change	NOUN
bptjm-66	353	3	in	in	ADP
bptjm-66	353	4	mean	mean	NOUN
bptjm-66	353	5	for	for	ADP
bptjm-66	353	6	the	the	DET
bptjm-66	353	7	pain	pain	NOUN
bptjm-66	353	8	score	score	NOUN
bptjm-66	353	9	between	between	ADP
bptjm-66	353	10	the	the	DET
bptjm-66	353	11	time	time	NOUN
bptjm-66	353	12	of	of	ADP
bptjm-66	353	13	randomization	randomization	NOUN
bptjm-66	353	14	and	and	CCONJ
bptjm-66	353	15	by	by	ADP
bptjm-66	353	16	the	the	DET
bptjm-66	353	17	end	end	NOUN
bptjm-66	353	18	of	of	ADP
bptjm-66	353	19	the	the	DET
bptjm-66	353	20	experiment	experiment	NOUN
bptjm-66	353	21	for	for	ADP
bptjm-66	353	22	photobiomodulation	photobiomodulation	NOUN
bptjm-66	353	23	therapy	therapy	NOUN
bptjm-66	353	24	and	and	CCONJ
bptjm-66	353	25	sham	sham	ADJ
bptjm-66	353	26	treatment	treatment	NOUN
bptjm-66	353	27	were	be	AUX
bptjm-66	353	28	-6.8	-6.8	NOUN
bptjm-66	353	29	and	and	CCONJ
bptjm-66	353	30	0.2	0.2	NUM
bptjm-66	353	31	respectively	respectively	ADV
bptjm-66	353	32	.	.	PUNCT
bptjm-66	354	1	the	the	DET
bptjm-66	354	2	higher	high	ADJ
bptjm-66	354	3	magnitude	magnitude	NOUN
bptjm-66	354	4	in	in	ADP
bptjm-66	354	5	a	a	DET
bptjm-66	354	6	change	change	NOUN
bptjm-66	354	7	of	of	ADP
bptjm-66	354	8	mean	mean	NOUN
bptjm-66	354	9	for	for	SCONJ
bptjm-66	354	10	photobiomodulation	photobiomodulation	NOUN
bptjm-66	354	11	therapy	therapy	NOUN
bptjm-66	354	12	demonstrates	demonstrate	VERB
bptjm-66	354	13	its	its	PRON
bptjm-66	354	14	efficacy	efficacy	NOUN
bptjm-66	354	15	in	in	ADP
bptjm-66	354	16	attenuating	attenuate	VERB
bptjm-66	354	17	neuropathic	neuropathic	ADJ
bptjm-66	354	18	pain	pain	NOUN
bptjm-66	354	19	symptoms	symptom	NOUN
bptjm-66	354	20	.	.	PUNCT
bptjm-66	355	1	heat	heat	NOUN
bptjm-66	355	2	is	be	AUX
bptjm-66	355	3	a	a	DET
bptjm-66	355	4	limitation	limitation	NOUN
bptjm-66	355	5	in	in	ADP
bptjm-66	355	6	receiving	receive	VERB
bptjm-66	355	7	optimal	optimal	ADJ
bptjm-66	355	8	results	result	NOUN
bptjm-66	355	9	as	as	ADP
bptjm-66	355	10	the	the	DET
bptjm-66	355	11	skin	skin	NOUN
bptjm-66	355	12	surface	surface	NOUN
bptjm-66	355	13	temperature	temperature	NOUN
bptjm-66	355	14	increases	increase	NOUN
bptjm-66	355	15	,	,	PUNCT
bptjm-66	355	16	and	and	CCONJ
bptjm-66	355	17	the	the	DET
bptjm-66	355	18	effects	effect	NOUN
bptjm-66	355	19	of	of	ADP
bptjm-66	355	20	photobiomodulation	photobiomodulation	NOUN
bptjm-66	355	21	decrease	decrease	NOUN
bptjm-66	355	22	.	.	PUNCT
bptjm-66	356	1	heat	heat	NOUN
bptjm-66	356	2	can	can	AUX
bptjm-66	356	3	be	be	AUX
bptjm-66	356	4	generated	generate	VERB
bptjm-66	356	5	through	through	ADP
bptjm-66	356	6	the	the	DET
bptjm-66	356	7	absorption	absorption	NOUN
bptjm-66	356	8	of	of	ADP
bptjm-66	356	9	radiation	radiation	NOUN
bptjm-66	356	10	by	by	ADP
bptjm-66	356	11	cells	cell	NOUN
bptjm-66	356	12	and	and	CCONJ
bptjm-66	356	13	tissue	tissue	NOUN
bptjm-66	356	14	targeted	target	VERB
bptjm-66	356	15	by	by	ADP
bptjm-66	356	16	the	the	DET
bptjm-66	356	17	laser	laser	NOUN
bptjm-66	356	18	.	.	PUNCT
bptjm-66	357	1	however	however	ADV
bptjm-66	357	2	,	,	PUNCT
bptjm-66	357	3	this	this	DET
bptjm-66	357	4	energy	energy	NOUN
bptjm-66	357	5	transfer	transfer	NOUN
bptjm-66	357	6	from	from	ADP
bptjm-66	357	7	the	the	DET
bptjm-66	357	8	photons	photon	NOUN
bptjm-66	357	9	produced	produce	VERB
bptjm-66	357	10	by	by	ADP
bptjm-66	357	11	the	the	DET
bptjm-66	357	12	laser	laser	NOUN
bptjm-66	357	13	that	that	PRON
bptjm-66	357	14	the	the	DET
bptjm-66	357	15	skin	skin	NOUN
bptjm-66	357	16	absorbs	absorb	VERB
bptjm-66	357	17	is	be	AUX
bptjm-66	357	18	allocated	allocate	VERB
bptjm-66	357	19	to	to	ADP
bptjm-66	357	20	non	non	ADJ
bptjm-66	357	21	-	-	ADJ
bptjm-66	357	22	targeted	targeted	ADJ
bptjm-66	357	23	tissues	tissue	NOUN
bptjm-66	357	24	that	that	PRON
bptjm-66	357	25	surround	surround	VERB
bptjm-66	357	26	the	the	DET
bptjm-66	357	27	targeted	target	VERB
bptjm-66	357	28	tissues	tissue	NOUN
bptjm-66	357	29	,	,	PUNCT
bptjm-66	357	30	leading	lead	VERB
bptjm-66	357	31	to	to	ADP
bptjm-66	357	32	the	the	DET
bptjm-66	357	33	unwanted	unwanted	ADJ
bptjm-66	357	34	production	production	NOUN
bptjm-66	357	35	of	of	ADP
bptjm-66	357	36	heat	heat	NOUN
bptjm-66	357	37	that	that	PRON
bptjm-66	357	38	reduces	reduce	VERB
bptjm-66	357	39	the	the	DET
bptjm-66	357	40	efficacy	efficacy	NOUN
bptjm-66	357	41	of	of	ADP
bptjm-66	357	42	photobiomodulation	photobiomodulation	NOUN
bptjm-66	357	43	.	.	PUNCT
bptjm-66	358	1	absorption	absorption	NOUN
bptjm-66	358	2	of	of	ADP
bptjm-66	358	3	light	light	NOUN
bptjm-66	358	4	is	be	AUX
bptjm-66	358	5	a	a	DET
bptjm-66	358	6	characteristic	characteristic	NOUN
bptjm-66	358	7	that	that	PRON
bptjm-66	358	8	is	be	AUX
bptjm-66	358	9	attributed	attribute	VERB
bptjm-66	358	10	to	to	ADP
bptjm-66	358	11	any	any	DET
bptjm-66	358	12	material	material	NOUN
bptjm-66	358	13	and	and	CCONJ
bptjm-66	358	14	,	,	PUNCT
bptjm-66	358	15	thus	thus	ADV
bptjm-66	358	16	,	,	PUNCT
bptjm-66	358	17	is	be	AUX
bptjm-66	358	18	impossible	impossible	ADJ
bptjm-66	358	19	to	to	PART
bptjm-66	358	20	completely	completely	ADV
bptjm-66	358	21	eradicate	eradicate	VERB
bptjm-66	358	22	.	.	PUNCT
bptjm-66	359	1	therefore	therefore	ADV
bptjm-66	359	2	,	,	PUNCT
bptjm-66	359	3	an	an	DET
bptjm-66	359	4	external	external	ADJ
bptjm-66	359	5	procedure	procedure	NOUN
bptjm-66	359	6	that	that	PRON
bptjm-66	359	7	decreases	decrease	VERB
bptjm-66	359	8	the	the	DET
bptjm-66	359	9	temperature	temperature	NOUN
bptjm-66	359	10	of	of	ADP
bptjm-66	359	11	the	the	DET
bptjm-66	359	12	surface	surface	NOUN
bptjm-66	359	13	of	of	ADP
bptjm-66	359	14	the	the	DET
bptjm-66	359	15	targeted	target	VERB
bptjm-66	359	16	tissue	tissue	NOUN
bptjm-66	359	17	must	must	AUX
bptjm-66	359	18	be	be	AUX
bptjm-66	359	19	performed	perform	VERB
bptjm-66	359	20	to	to	PART
bptjm-66	359	21	induce	induce	VERB
bptjm-66	359	22	a	a	DET
bptjm-66	359	23	substantial	substantial	ADJ
bptjm-66	359	24	response	response	NOUN
bptjm-66	359	25	toward	toward	ADP
bptjm-66	359	26	photobiomodulation	photobiomodulation	NOUN
bptjm-66	359	27	.	.	PUNCT
bptjm-66	360	1	other	other	ADJ
bptjm-66	360	2	limiting	limit	VERB
bptjm-66	360	3	factors	factor	NOUN
bptjm-66	360	4	include	include	VERB
bptjm-66	360	5	reflection	reflection	NOUN
bptjm-66	360	6	and	and	CCONJ
bptjm-66	360	7	scattering60	scattering60	NOUN
bptjm-66	360	8	.	.	PUNCT
bptjm-66	361	1	reflection	reflection	NOUN
bptjm-66	361	2	of	of	ADP
bptjm-66	361	3	light	light	NOUN
bptjm-66	361	4	from	from	ADP
bptjm-66	361	5	the	the	DET
bptjm-66	361	6	targeted	target	VERB
bptjm-66	361	7	tissue	tissue	NOUN
bptjm-66	361	8	implies	imply	VERB
bptjm-66	361	9	that	that	SCONJ
bptjm-66	361	10	the	the	DET
bptjm-66	361	11	energy	energy	NOUN
bptjm-66	361	12	provided	provide	VERB
bptjm-66	361	13	by	by	ADP
bptjm-66	361	14	the	the	DET
bptjm-66	361	15	light	light	NOUN
bptjm-66	361	16	is	be	AUX
bptjm-66	361	17	not	not	PART
bptjm-66	361	18	being	be	AUX
bptjm-66	361	19	completely	completely	ADV
bptjm-66	361	20	absorbed	absorb	VERB
bptjm-66	361	21	and	and	CCONJ
bptjm-66	361	22	that	that	SCONJ
bptjm-66	361	23	energy	energy	NOUN
bptjm-66	361	24	is	be	AUX
bptjm-66	361	25	erroneously	erroneously	ADV
bptjm-66	361	26	expended	expend	VERB
bptjm-66	361	27	towards	towards	ADP
bptjm-66	361	28	non	non	ADJ
bptjm-66	361	29	-	-	ADJ
bptjm-66	361	30	targeted	targeted	ADJ
bptjm-66	361	31	tissues	tissue	NOUN
bptjm-66	361	32	.	.	PUNCT
bptjm-66	362	1	scattering	scatter	VERB
bptjm-66	362	2	on	on	ADP
bptjm-66	362	3	the	the	DET
bptjm-66	362	4	other	other	ADJ
bptjm-66	362	5	hand	hand	NOUN
bptjm-66	362	6	disperses	disperse	VERB
bptjm-66	362	7	light	light	NOUN
bptjm-66	362	8	in	in	ADP
bptjm-66	362	9	different	different	ADJ
bptjm-66	362	10	directions	direction	NOUN
bptjm-66	362	11	due	due	ADP
bptjm-66	362	12	to	to	ADP
bptjm-66	362	13	wave	wave	NOUN
bptjm-66	362	14	-	-	PUNCT
bptjm-66	362	15	particle	particle	NOUN
bptjm-66	362	16	interactions	interaction	NOUN
bptjm-66	362	17	.	.	PUNCT
bptjm-66	363	1	this	this	PRON
bptjm-66	363	2	is	be	AUX
bptjm-66	363	3	significant	significant	ADJ
bptjm-66	363	4	to	to	ADP
bptjm-66	363	5	photobiomodulation	photobiomodulation	NOUN
bptjm-66	363	6	efficiency	efficiency	NOUN
bptjm-66	363	7	because	because	SCONJ
bptjm-66	363	8	varying	vary	VERB
bptjm-66	363	9	wavelengths	wavelength	NOUN
bptjm-66	363	10	of	of	ADP
bptjm-66	363	11	light	light	ADJ
bptjm-66	363	12	pertain	pertain	NOUN
bptjm-66	363	13	to	to	ADP
bptjm-66	363	14	different	different	ADJ
bptjm-66	363	15	scattering	scattering	NOUN
bptjm-66	363	16	properties	property	NOUN
bptjm-66	363	17	when	when	SCONJ
bptjm-66	363	18	penetrating	penetrate	VERB
bptjm-66	363	19	tissue	tissue	NOUN
bptjm-66	363	20	,	,	PUNCT
bptjm-66	363	21	diffusing	diffuse	VERB
bptjm-66	363	22	collimated	collimate	VERB
bptjm-66	363	23	beams	beam	NOUN
bptjm-66	363	24	into	into	ADP
bptjm-66	363	25	a	a	DET
bptjm-66	363	26	cloud	cloud	NOUN
bptjm-66	363	27	of	of	ADP
bptjm-66	363	28	photons	photon	NOUN
bptjm-66	363	29	.	.	PUNCT
bptjm-66	364	1	this	this	PRON
bptjm-66	364	2	dilutes	dilute	VERB
bptjm-66	364	3	the	the	DET
bptjm-66	364	4	potency	potency	NOUN
bptjm-66	364	5	of	of	ADP
bptjm-66	364	6	the	the	DET
bptjm-66	364	7	light	light	NOUN
bptjm-66	364	8	because	because	SCONJ
bptjm-66	364	9	rather	rather	ADV
bptjm-66	364	10	than	than	ADP
bptjm-66	364	11	focusing	focus	VERB
bptjm-66	364	12	on	on	ADP
bptjm-66	364	13	a	a	DET
bptjm-66	364	14	single	single	ADJ
bptjm-66	364	15	area	area	NOUN
bptjm-66	364	16	,	,	PUNCT
bptjm-66	364	17	surrounding	surround	VERB
bptjm-66	364	18	non	non	ADJ
bptjm-66	364	19	-	-	ADJ
bptjm-66	364	20	target	target	ADJ
bptjm-66	364	21	tissue	tissue	NOUN
bptjm-66	364	22	receives	receive	VERB
bptjm-66	364	23	unnecessary	unnecessary	ADJ
bptjm-66	364	24	treatment	treatment	NOUN
bptjm-66	364	25	.	.	PUNCT
bptjm-66	365	1	recent	recent	ADJ
bptjm-66	365	2	debates	debate	NOUN
bptjm-66	365	3	on	on	ADP
bptjm-66	365	4	using	use	VERB
bptjm-66	365	5	pulsed	pulse	VERB
bptjm-66	365	6	waves	wave	NOUN
bptjm-66	365	7	instead	instead	ADV
bptjm-66	365	8	of	of	ADP
bptjm-66	365	9	continuous	continuous	ADJ
bptjm-66	365	10	waves	wave	NOUN
bptjm-66	365	11	to	to	PART
bptjm-66	365	12	maximize	maximize	VERB
bptjm-66	365	13	therapeutic	therapeutic	ADJ
bptjm-66	365	14	efficiency	efficiency	NOUN
bptjm-66	365	15	have	have	AUX
bptjm-66	365	16	emerged	emerge	VERB
bptjm-66	365	17	because	because	SCONJ
bptjm-66	365	18	pulsed	pulse	VERB
bptjm-66	365	19	waves	wave	NOUN
bptjm-66	365	20	are	be	AUX
bptjm-66	365	21	less	less	ADV
bptjm-66	365	22	thermally	thermally	ADV
bptjm-66	365	23	strenuous	strenuous	ADJ
bptjm-66	365	24	to	to	PART
bptjm-66	365	25	irradiated	irradiated	VERB
bptjm-66	365	26	berkeley	berkeley	PROPN
bptjm-66	365	27	pharma	pharma	PROPN
bptjm-66	365	28	tech	tech	NOUN
bptjm-66	365	29	journal	journal	NOUN
bptjm-66	365	30	of	of	ADP
bptjm-66	365	31	medicine	medicine	NOUN
bptjm-66	365	32	|	|	ADV
bptjm-66	365	33	25	25	NUM
bptjm-66	365	34	tissues	tissue	NOUN
bptjm-66	365	35	which	which	PRON
bptjm-66	365	36	may	may	AUX
bptjm-66	365	37	improve	improve	VERB
bptjm-66	365	38	deep	deep	ADJ
bptjm-66	365	39	tissue	tissue	NOUN
bptjm-66	365	40	penetration	penetration	NOUN
bptjm-66	365	41	,	,	PUNCT
bptjm-66	365	42	but	but	CCONJ
bptjm-66	365	43	this	this	PRON
bptjm-66	365	44	is	be	AUX
bptjm-66	365	45	only	only	ADV
bptjm-66	365	46	conjecture	conjecture	NOUN
bptjm-66	365	47	since	since	SCONJ
bptjm-66	365	48	evidence	evidence	NOUN
bptjm-66	365	49	for	for	ADP
bptjm-66	365	50	this	this	DET
bptjm-66	365	51	hypothesis	hypothesis	NOUN
bptjm-66	365	52	is	be	AUX
bptjm-66	365	53	scarce	scarce	ADJ
bptjm-66	365	54	.	.	PUNCT
bptjm-66	366	1	photobiomodulation	photobiomodulation	NOUN
bptjm-66	366	2	has	have	AUX
bptjm-66	366	3	also	also	ADV
bptjm-66	366	4	been	be	AUX
bptjm-66	366	5	studied	study	VERB
bptjm-66	366	6	in	in	ADP
bptjm-66	366	7	the	the	DET
bptjm-66	366	8	context	context	NOUN
bptjm-66	366	9	of	of	ADP
bptjm-66	366	10	its	its	PRON
bptjm-66	366	11	promising	promising	ADJ
bptjm-66	366	12	effects	effect	NOUN
bptjm-66	366	13	on	on	ADP
bptjm-66	366	14	the	the	DET
bptjm-66	366	15	musculoskeletal	musculoskeletal	ADJ
bptjm-66	366	16	system	system	NOUN
bptjm-66	366	17	.	.	PUNCT
bptjm-66	367	1	due	due	ADP
bptjm-66	367	2	to	to	ADP
bptjm-66	367	3	its	its	PRON
bptjm-66	367	4	cellular	cellular	ADJ
bptjm-66	367	5	activity	activity	NOUN
bptjm-66	367	6	enhancement	enhancement	NOUN
bptjm-66	367	7	capabilities	capability	NOUN
bptjm-66	367	8	,	,	PUNCT
bptjm-66	367	9	photobiomodulation	photobiomodulation	NOUN
bptjm-66	367	10	is	be	AUX
bptjm-66	367	11	often	often	ADV
bptjm-66	367	12	used	use	VERB
bptjm-66	367	13	in	in	ADP
bptjm-66	367	14	recovering	recover	VERB
bptjm-66	367	15	athletes	athlete	NOUN
bptjm-66	367	16	affected	affect	VERB
bptjm-66	367	17	by	by	ADP
bptjm-66	367	18	musculoskeletal	musculoskeletal	ADJ
bptjm-66	367	19	-	-	PUNCT
bptjm-66	367	20	related	relate	VERB
bptjm-66	367	21	issues	issue	NOUN
bptjm-66	367	22	.	.	PUNCT
bptjm-66	368	1	it	it	PRON
bptjm-66	368	2	has	have	AUX
bptjm-66	368	3	been	be	AUX
bptjm-66	368	4	found	find	VERB
bptjm-66	368	5	that	that	SCONJ
bptjm-66	368	6	when	when	SCONJ
bptjm-66	368	7	using	use	VERB
bptjm-66	368	8	an	an	DET
bptjm-66	368	9	810	810	NUM
bptjm-66	368	10	nm	nm	NOUN
bptjm-66	368	11	laser	laser	NOUN
bptjm-66	368	12	on	on	ADP
bptjm-66	368	13	athletes	athlete	NOUN
bptjm-66	368	14	to	to	PART
bptjm-66	368	15	observe	observe	VERB
bptjm-66	368	16	muscle	muscle	NOUN
bptjm-66	368	17	performance	performance	NOUN
bptjm-66	368	18	and	and	CCONJ
bptjm-66	368	19	postexercise	postexercise	ADJ
bptjm-66	368	20	recovery	recovery	NOUN
bptjm-66	368	21	,	,	PUNCT
bptjm-66	368	22	50	50	NUM
bptjm-66	368	23	j	j	NOUN
bptjm-66	368	24	is	be	AUX
bptjm-66	368	25	the	the	DET
bptjm-66	368	26	optimum	optimum	ADJ
bptjm-66	368	27	dosage	dosage	NOUN
bptjm-66	368	28	.	.	PUNCT
bptjm-66	369	1	the	the	DET
bptjm-66	369	2	study	study	NOUN
bptjm-66	369	3	only	only	ADV
bptjm-66	369	4	focused	focus	VERB
bptjm-66	369	5	on	on	ADP
bptjm-66	369	6	three	three	NUM
bptjm-66	369	7	different	different	ADJ
bptjm-66	369	8	doses	dose	NOUN
bptjm-66	369	9	at	at	ADP
bptjm-66	369	10	10	10	NUM
bptjm-66	369	11	j	j	PROPN
bptjm-66	369	12	,	,	PUNCT
bptjm-66	369	13	30	30	NUM
bptjm-66	369	14	j	j	PROPN
bptjm-66	369	15	,	,	PUNCT
bptjm-66	369	16	and	and	CCONJ
bptjm-66	369	17	50	50	NUM
bptjm-66	369	18	j	j	NOUN
bptjm-66	369	19	,	,	PUNCT
bptjm-66	369	20	which	which	PRON
bptjm-66	369	21	implies	imply	VERB
bptjm-66	369	22	that	that	SCONJ
bptjm-66	369	23	an	an	DET
bptjm-66	369	24	upper	upper	ADJ
bptjm-66	369	25	limit	limit	NOUN
bptjm-66	369	26	is	be	AUX
bptjm-66	369	27	still	still	ADV
bptjm-66	369	28	unknown	unknown	ADJ
bptjm-66	369	29	and	and	CCONJ
bptjm-66	369	30	that	that	SCONJ
bptjm-66	369	31	a	a	DET
bptjm-66	369	32	higher	high	ADJ
bptjm-66	369	33	dose	dose	NOUN
bptjm-66	369	34	may	may	AUX
bptjm-66	369	35	be	be	AUX
bptjm-66	369	36	conducive	conducive	ADJ
bptjm-66	369	37	to	to	ADP
bptjm-66	369	38	more	more	ADJ
bptjm-66	369	39	benefits	benefit	NOUN
bptjm-66	369	40	.	.	PUNCT
bptjm-66	370	1	similarly	similarly	ADV
bptjm-66	370	2	,	,	PUNCT
bptjm-66	370	3	an	an	DET
bptjm-66	370	4	830	830	NUM
bptjm-66	370	5	nm	nm	NOUN
bptjm-66	370	6	laser	laser	NOUN
bptjm-66	370	7	was	be	AUX
bptjm-66	370	8	used	use	VERB
bptjm-66	370	9	on	on	ADP
bptjm-66	370	10	another	another	DET
bptjm-66	370	11	group	group	NOUN
bptjm-66	370	12	of	of	ADP
bptjm-66	370	13	athletes	athlete	NOUN
bptjm-66	370	14	before	before	ADP
bptjm-66	370	15	and	and	CCONJ
bptjm-66	370	16	after	after	ADP
bptjm-66	370	17	exercise	exercise	NOUN
bptjm-66	370	18	divided	divide	VERB
bptjm-66	370	19	into	into	ADP
bptjm-66	370	20	three	three	NUM
bptjm-66	370	21	groups	group	NOUN
bptjm-66	370	22	:	:	PUNCT
bptjm-66	370	23	placebo	placebo	NOUN
bptjm-66	370	24	,	,	PUNCT
bptjm-66	370	25	pre	pre	ADJ
bptjm-66	370	26	-	-	ADJ
bptjm-66	370	27	fatigue	fatigue	ADJ
bptjm-66	370	28	laser	laser	NOUN
bptjm-66	370	29	,	,	PUNCT
bptjm-66	370	30	and	and	CCONJ
bptjm-66	370	31	post	post	ADJ
bptjm-66	370	32	-	-	ADJ
bptjm-66	370	33	fatigue	fatigue	ADJ
bptjm-66	370	34	laser	laser	NOUN
bptjm-66	370	35	.	.	PUNCT
bptjm-66	371	1	this	this	DET
bptjm-66	371	2	wavelength	wavelength	NOUN
bptjm-66	371	3	of	of	ADP
bptjm-66	371	4	light	light	NOUN
bptjm-66	371	5	reduced	reduce	VERB
bptjm-66	371	6	serum	serum	NOUN
bptjm-66	371	7	lactate	lactate	NOUN
bptjm-66	371	8	and	and	CCONJ
bptjm-66	371	9	creatine	creatine	PROPN
bptjm-66	371	10	kinase	kinase	PROPN
bptjm-66	371	11	levels	level	NOUN
bptjm-66	371	12	in	in	ADP
bptjm-66	371	13	both	both	PRON
bptjm-66	371	14	pre	pre	ADJ
bptjm-66	371	15	-	-	ADJ
bptjm-66	371	16	fatigue	fatigue	ADJ
bptjm-66	371	17	laser	laser	NOUN
bptjm-66	371	18	and	and	CCONJ
bptjm-66	371	19	post	post	ADJ
bptjm-66	371	20	-	-	ADJ
bptjm-66	371	21	fatigue	fatigue	ADJ
bptjm-66	371	22	laser	laser	NOUN
bptjm-66	371	23	groups	group	NOUN
bptjm-66	371	24	.	.	PUNCT
bptjm-66	372	1	however	however	ADV
bptjm-66	372	2	,	,	PUNCT
bptjm-66	372	3	a	a	DET
bptjm-66	372	4	more	more	ADV
bptjm-66	372	5	significant	significant	ADJ
bptjm-66	372	6	reduction	reduction	NOUN
bptjm-66	372	7	was	be	AUX
bptjm-66	372	8	observed	observe	VERB
bptjm-66	372	9	in	in	ADP
bptjm-66	372	10	the	the	DET
bptjm-66	372	11	post	post	ADJ
bptjm-66	372	12	-	-	ADJ
bptjm-66	372	13	fatigue	fatigue	ADJ
bptjm-66	372	14	laser	laser	NOUN
bptjm-66	372	15	group	group	NOUN
bptjm-66	372	16	.	.	PUNCT
bptjm-66	373	1	it	it	PRON
bptjm-66	373	2	has	have	AUX
bptjm-66	373	3	also	also	ADV
bptjm-66	373	4	been	be	AUX
bptjm-66	373	5	found	find	VERB
bptjm-66	373	6	that	that	SCONJ
bptjm-66	373	7	the	the	DET
bptjm-66	373	8	source	source	NOUN
bptjm-66	373	9	of	of	ADP
bptjm-66	373	10	light	light	NOUN
bptjm-66	373	11	is	be	AUX
bptjm-66	373	12	responsible	responsible	ADJ
bptjm-66	373	13	for	for	ADP
bptjm-66	373	14	the	the	DET
bptjm-66	373	15	resulting	result	VERB
bptjm-66	373	16	beneficial	beneficial	ADJ
bptjm-66	373	17	effects	effect	NOUN
bptjm-66	373	18	of	of	ADP
bptjm-66	373	19	photobiomodulation	photobiomodulation	NOUN
bptjm-66	373	20	.	.	PUNCT
bptjm-66	374	1	in	in	ADP
bptjm-66	374	2	a	a	DET
bptjm-66	374	3	study	study	NOUN
bptjm-66	374	4	observing	observe	VERB
bptjm-66	374	5	musculoskeletal	musculoskeletal	ADJ
bptjm-66	374	6	performance	performance	NOUN
bptjm-66	374	7	and	and	CCONJ
bptjm-66	374	8	postexercise	postexercise	ADJ
bptjm-66	374	9	recovery	recovery	NOUN
bptjm-66	374	10	in	in	ADP
bptjm-66	374	11	healthy	healthy	ADJ
bptjm-66	374	12	males	male	NOUN
bptjm-66	374	13	,	,	PUNCT
bptjm-66	374	14	a	a	DET
bptjm-66	374	15	30	30	NUM
bptjm-66	374	16	j	j	PROPN
bptjm-66	374	17	dose	dose	NOUN
bptjm-66	374	18	provided	provide	VERB
bptjm-66	374	19	the	the	DET
bptjm-66	374	20	best	good	ADJ
bptjm-66	374	21	results	result	NOUN
bptjm-66	374	22	by	by	ADP
bptjm-66	374	23	decreasing	decrease	VERB
bptjm-66	374	24	delayed	delay	VERB
bptjm-66	374	25	-	-	PUNCT
bptjm-66	374	26	onset	onset	NOUN
bptjm-66	374	27	muscle	muscle	NOUN
bptjm-66	374	28	soreness	soreness	NOUN
bptjm-66	374	29	and	and	CCONJ
bptjm-66	374	30	improving	improve	VERB
bptjm-66	374	31	biochemical	biochemical	ADJ
bptjm-66	374	32	markers	marker	NOUN
bptjm-66	374	33	related	relate	VERB
bptjm-66	374	34	to	to	ADP
bptjm-66	374	35	musculoskeletal	musculoskeletal	ADJ
bptjm-66	374	36	damage61	damage61	ADJ
bptjm-66	374	37	.	.	PUNCT
bptjm-66	375	1	therefore	therefore	ADV
bptjm-66	375	2	,	,	PUNCT
bptjm-66	375	3	maximum	maximum	ADJ
bptjm-66	375	4	musculoskeletal	musculoskeletal	ADJ
bptjm-66	375	5	system	system	NOUN
bptjm-66	375	6	recovery	recovery	NOUN
bptjm-66	375	7	benefits	benefit	NOUN
bptjm-66	375	8	stemming	stem	VERB
bptjm-66	375	9	from	from	ADP
bptjm-66	375	10	photobiomodulation	photobiomodulation	NOUN
bptjm-66	375	11	therapy	therapy	NOUN
bptjm-66	375	12	are	be	AUX
bptjm-66	375	13	empirically	empirically	ADV
bptjm-66	375	14	attainable	attainable	ADJ
bptjm-66	375	15	through	through	ADP
bptjm-66	375	16	optimizing	optimize	VERB
bptjm-66	375	17	wavelength	wavelength	NOUN
bptjm-66	375	18	,	,	PUNCT
bptjm-66	375	19	light	light	ADJ
bptjm-66	375	20	source	source	NOUN
bptjm-66	375	21	,	,	PUNCT
bptjm-66	375	22	and	and	CCONJ
bptjm-66	375	23	application	application	NOUN
bptjm-66	375	24	during	during	ADP
bptjm-66	375	25	fatigue	fatigue	NOUN
bptjm-66	375	26	.	.	PUNCT
bptjm-66	376	1	4.4	4.4	NUM
bptjm-66	376	2	passive	passive	ADJ
bptjm-66	376	3	treatment	treatment	NOUN
bptjm-66	376	4	capsaicin	capsaicin	NOUN
bptjm-66	376	5	patch	patch	NOUN
bptjm-66	376	6	is	be	AUX
bptjm-66	376	7	an	an	DET
bptjm-66	376	8	effective	effective	ADJ
bptjm-66	376	9	and	and	CCONJ
bptjm-66	376	10	accessible	accessible	ADJ
bptjm-66	376	11	treatment	treatment	NOUN
bptjm-66	376	12	for	for	ADP
bptjm-66	376	13	neuropathic	neuropathic	ADJ
bptjm-66	376	14	pain	pain	NOUN
bptjm-66	376	15	.	.	PUNCT
bptjm-66	377	1	capsaicin	capsaicin	NOUN
bptjm-66	377	2	is	be	AUX
bptjm-66	377	3	a	a	DET
bptjm-66	377	4	compound	compound	NOUN
bptjm-66	377	5	that	that	PRON
bptjm-66	377	6	when	when	SCONJ
bptjm-66	377	7	used	use	VERB
bptjm-66	377	8	topically	topically	ADV
bptjm-66	377	9	,	,	PUNCT
bptjm-66	377	10	attenuates	attenuate	VERB
bptjm-66	377	11	cutaneous	cutaneous	ADJ
bptjm-66	377	12	hypersensitivity	hypersensitivity	NOUN
bptjm-66	377	13	to	to	PART
bptjm-66	377	14	heat	heat	VERB
bptjm-66	377	15	and	and	CCONJ
bptjm-66	377	16	mechanical	mechanical	ADJ
bptjm-66	377	17	stimuli	stimulus	NOUN
bptjm-66	377	18	through	through	ADP
bptjm-66	377	19	the	the	DET
bptjm-66	377	20	degeneration	degeneration	NOUN
bptjm-66	377	21	of	of	ADP
bptjm-66	377	22	nerve	nerve	NOUN
bptjm-66	377	23	fibers	fiber	NOUN
bptjm-66	377	24	.	.	PUNCT
bptjm-66	378	1	trpv1	trpv1	ADJ
bptjm-66	378	2	,	,	PUNCT
bptjm-66	378	3	a	a	DET
bptjm-66	378	4	cationic	cationic	ADJ
bptjm-66	378	5	channel	channel	NOUN
bptjm-66	378	6	that	that	PRON
bptjm-66	378	7	is	be	AUX
bptjm-66	378	8	activated	activate	VERB
bptjm-66	378	9	by	by	ADP
bptjm-66	378	10	capsaicin	capsaicin	PROPN
bptjm-66	378	11	,	,	PUNCT
bptjm-66	378	12	stimulates	stimulate	VERB
bptjm-66	378	13	the	the	DET
bptjm-66	378	14	increased	increase	VERB
bptjm-66	378	15	movement	movement	NOUN
bptjm-66	378	16	of	of	ADP
bptjm-66	378	17	sodium	sodium	NOUN
bptjm-66	378	18	and	and	CCONJ
bptjm-66	378	19	calcium	calcium	NOUN
bptjm-66	378	20	ions	ion	NOUN
bptjm-66	378	21	into	into	ADP
bptjm-66	378	22	sensory	sensory	ADJ
bptjm-66	378	23	cells	cell	NOUN
bptjm-66	378	24	that	that	PRON
bptjm-66	378	25	depolarize	depolarize	VERB
bptjm-66	378	26	nociceptive	nociceptive	ADJ
bptjm-66	378	27	neurons	neuron	NOUN
bptjm-66	378	28	and	and	CCONJ
bptjm-66	378	29	cause	cause	VERB
bptjm-66	378	30	action	action	NOUN
bptjm-66	378	31	potential	potential	ADJ
bptjm-66	378	32	firing	firing	NOUN
bptjm-66	378	33	.	.	PUNCT
bptjm-66	379	1	this	this	PRON
bptjm-66	379	2	creates	create	VERB
bptjm-66	379	3	an	an	DET
bptjm-66	379	4	analgesic	analgesic	ADJ
bptjm-66	379	5	effect	effect	NOUN
bptjm-66	379	6	that	that	PRON
bptjm-66	379	7	desensitizes	desensitize	VERB
bptjm-66	379	8	the	the	DET
bptjm-66	379	9	nociceptive	nociceptive	ADJ
bptjm-66	379	10	areas	area	NOUN
bptjm-66	379	11	to	to	PART
bptjm-66	379	12	which	which	PRON
bptjm-66	379	13	the	the	DET
bptjm-66	379	14	patch	patch	NOUN
bptjm-66	379	15	or	or	CCONJ
bptjm-66	379	16	topical	topical	ADJ
bptjm-66	379	17	treatment	treatment	NOUN
bptjm-66	379	18	is	be	AUX
bptjm-66	379	19	applied	apply	VERB
bptjm-66	379	20	to	to	ADP
bptjm-66	379	21	.	.	PUNCT
bptjm-66	380	1	berkeley	berkeley	PROPN
bptjm-66	380	2	pharma	pharma	PROPN
bptjm-66	380	3	tech	tech	PROPN
bptjm-66	380	4	journal	journal	NOUN
bptjm-66	380	5	of	of	ADP
bptjm-66	380	6	medicine	medicine	NOUN
bptjm-66	380	7	|	|	ADV
bptjm-66	380	8	26	26	NUM
bptjm-66	380	9	figure	figure	NOUN
bptjm-66	380	10	8	8	NUM
bptjm-66	380	11	.	.	PUNCT
bptjm-66	381	1	capsaicin	capsaicin	NOUN
bptjm-66	381	2	mechanism	mechanism	NOUN
bptjm-66	381	3	of	of	ADP
bptjm-66	381	4	action	action	NOUN
bptjm-66	381	5	unlike	unlike	ADP
bptjm-66	381	6	other	other	ADJ
bptjm-66	381	7	topical	topical	ADJ
bptjm-66	381	8	alternatives	alternative	NOUN
bptjm-66	381	9	,	,	PUNCT
bptjm-66	381	10	patches	patch	NOUN
bptjm-66	381	11	are	be	AUX
bptjm-66	381	12	unique	unique	ADJ
bptjm-66	381	13	in	in	ADP
bptjm-66	381	14	their	their	PRON
bptjm-66	381	15	method	method	NOUN
bptjm-66	381	16	of	of	ADP
bptjm-66	381	17	drug	drug	NOUN
bptjm-66	381	18	delivery	delivery	NOUN
bptjm-66	381	19	as	as	SCONJ
bptjm-66	381	20	they	they	PRON
bptjm-66	381	21	can	can	AUX
bptjm-66	381	22	provide	provide	VERB
bptjm-66	381	23	extended	extended	ADJ
bptjm-66	381	24	release	release	NOUN
bptjm-66	381	25	of	of	ADP
bptjm-66	381	26	the	the	DET
bptjm-66	381	27	drug	drug	NOUN
bptjm-66	381	28	in	in	ADP
bptjm-66	381	29	regulated	regulated	ADJ
bptjm-66	381	30	concentrations	concentration	NOUN
bptjm-66	381	31	to	to	PART
bptjm-66	381	32	prevent	prevent	VERB
bptjm-66	381	33	overdose	overdose	ADV
bptjm-66	381	34	and	and	CCONJ
bptjm-66	381	35	unwanted	unwanted	ADJ
bptjm-66	381	36	prolonged	prolonged	ADJ
bptjm-66	381	37	effects	effect	NOUN
bptjm-66	381	38	.	.	PUNCT
bptjm-66	382	1	neuropathic	neuropathic	ADJ
bptjm-66	382	2	pain	pain	NOUN
bptjm-66	382	3	is	be	AUX
bptjm-66	382	4	a	a	DET
bptjm-66	382	5	type	type	NOUN
bptjm-66	382	6	of	of	ADP
bptjm-66	382	7	chronic	chronic	ADJ
bptjm-66	382	8	pain	pain	NOUN
bptjm-66	382	9	.	.	PUNCT
bptjm-66	383	1	therefore	therefore	ADV
bptjm-66	383	2	,	,	PUNCT
bptjm-66	383	3	capsaicin	capsaicin	NOUN
bptjm-66	383	4	effectively	effectively	ADV
bptjm-66	383	5	attenuates	attenuate	VERB
bptjm-66	383	6	pain	pain	NOUN
bptjm-66	383	7	for	for	ADP
bptjm-66	383	8	longer	long	ADJ
bptjm-66	383	9	periods	period	NOUN
bptjm-66	383	10	depending	depend	VERB
bptjm-66	383	11	on	on	ADP
bptjm-66	383	12	several	several	ADJ
bptjm-66	383	13	factors	factor	NOUN
bptjm-66	383	14	that	that	PRON
bptjm-66	383	15	are	be	AUX
bptjm-66	383	16	being	be	AUX
bptjm-66	383	17	researched	research	VERB
bptjm-66	383	18	in	in	ADP
bptjm-66	383	19	recent	recent	ADJ
bptjm-66	383	20	developments	development	NOUN
bptjm-66	383	21	.	.	PUNCT
bptjm-66	384	1	the	the	DET
bptjm-66	384	2	duration	duration	NOUN
bptjm-66	384	3	of	of	ADP
bptjm-66	384	4	the	the	DET
bptjm-66	384	5	analgesic	analgesic	ADJ
bptjm-66	384	6	effect	effect	NOUN
bptjm-66	384	7	is	be	AUX
bptjm-66	384	8	affected	affect	VERB
bptjm-66	384	9	by	by	ADP
bptjm-66	384	10	the	the	DET
bptjm-66	384	11	concentration	concentration	NOUN
bptjm-66	384	12	of	of	ADP
bptjm-66	384	13	capsaicin	capsaicin	NOUN
bptjm-66	384	14	,	,	PUNCT
bptjm-66	384	15	capsaicin	capsaicin	NOUN
bptjm-66	384	16	-	-	PUNCT
bptjm-66	384	17	induced	induce	VERB
bptjm-66	384	18	calpain	calpain	NOUN
bptjm-66	384	19	-	-	PUNCT
bptjm-66	384	20	mediated	mediate	VERB
bptjm-66	384	21	ablation	ablation	NOUN
bptjm-66	384	22	of	of	ADP
bptjm-66	384	23	axonal	axonal	ADJ
bptjm-66	384	24	terminals	terminal	NOUN
bptjm-66	384	25	,	,	PUNCT
bptjm-66	384	26	axonal	axonal	ADJ
bptjm-66	384	27	mitochondrial	mitochondrial	ADJ
bptjm-66	384	28	dysfunction	dysfunction	NOUN
bptjm-66	384	29	,	,	PUNCT
bptjm-66	384	30	and	and	CCONJ
bptjm-66	384	31	microtubule	microtubule	NOUN
bptjm-66	384	32	disorganization62	disorganization62	NOUN
bptjm-66	384	33	.	.	PUNCT
bptjm-66	385	1	calpain	calpain	NOUN
bptjm-66	385	2	is	be	AUX
bptjm-66	385	3	a	a	DET
bptjm-66	385	4	protease	protease	NOUN
bptjm-66	385	5	activated	activate	VERB
bptjm-66	385	6	by	by	ADP
bptjm-66	385	7	the	the	DET
bptjm-66	385	8	influx	influx	NOUN
bptjm-66	385	9	of	of	ADP
bptjm-66	385	10	overbearing	overbearing	ADJ
bptjm-66	385	11	levels	level	NOUN
bptjm-66	385	12	of	of	ADP
bptjm-66	385	13	calcium	calcium	NOUN
bptjm-66	385	14	into	into	ADP
bptjm-66	385	15	the	the	DET
bptjm-66	385	16	cell	cell	NOUN
bptjm-66	385	17	which	which	PRON
bptjm-66	385	18	cleaves	cleave	VERB
bptjm-66	385	19	cytoplasmic	cytoplasmic	ADJ
bptjm-66	385	20	and	and	CCONJ
bptjm-66	385	21	nuclear	nuclear	ADJ
bptjm-66	385	22	substrates	substrate	NOUN
bptjm-66	385	23	causing	cause	VERB
bptjm-66	385	24	cells	cell	NOUN
bptjm-66	385	25	to	to	PART
bptjm-66	385	26	end	end	VERB
bptjm-66	385	27	up	up	ADP
bptjm-66	385	28	undergoing	undergo	VERB
bptjm-66	385	29	apoptosis	apoptosis	NOUN
bptjm-66	385	30	.	.	PUNCT
bptjm-66	386	1	while	while	SCONJ
bptjm-66	386	2	calpain	calpain	NOUN
bptjm-66	386	3	enzymes	enzyme	NOUN
bptjm-66	386	4	are	be	AUX
bptjm-66	386	5	involved	involve	VERB
bptjm-66	386	6	in	in	ADP
bptjm-66	386	7	processes	process	NOUN
bptjm-66	386	8	such	such	ADJ
bptjm-66	386	9	as	as	ADP
bptjm-66	386	10	cell	cell	NOUN
bptjm-66	386	11	division	division	NOUN
bptjm-66	386	12	,	,	PUNCT
bptjm-66	386	13	differentiation	differentiation	NOUN
bptjm-66	386	14	,	,	PUNCT
bptjm-66	386	15	and	and	CCONJ
bptjm-66	386	16	migration	migration	NOUN
bptjm-66	386	17	,	,	PUNCT
bptjm-66	386	18	their	their	PRON
bptjm-66	386	19	apoptotic	apoptotic	ADJ
bptjm-66	386	20	response	response	NOUN
bptjm-66	386	21	allows	allow	VERB
bptjm-66	386	22	for	for	ADP
bptjm-66	386	23	protection	protection	NOUN
bptjm-66	386	24	from	from	ADP
bptjm-66	386	25	other	other	ADJ
bptjm-66	386	26	malignant	malignant	ADJ
bptjm-66	386	27	cell	cell	NOUN
bptjm-66	386	28	lines	line	NOUN
bptjm-66	386	29	including	include	VERB
bptjm-66	386	30	hepatocarcinoma	hepatocarcinoma	NOUN
bptjm-66	386	31	,	,	PUNCT
bptjm-66	386	32	prostate	prostate	NOUN
bptjm-66	386	33	cancer	cancer	NOUN
bptjm-66	386	34	,	,	PUNCT
bptjm-66	386	35	human	human	ADJ
bptjm-66	386	36	glioma	glioma	NOUN
bptjm-66	386	37	,	,	PUNCT
bptjm-66	386	38	breast	breast	NOUN
bptjm-66	386	39	cancer	cancer	NOUN
bptjm-66	386	40	cells	cell	NOUN
bptjm-66	386	41	,	,	PUNCT
bptjm-66	386	42	and	and	CCONJ
bptjm-66	386	43	human	human	ADJ
bptjm-66	386	44	gastric	gastric	ADJ
bptjm-66	386	45	cancer	cancer	NOUN
bptjm-66	386	46	.	.	PUNCT
bptjm-66	387	1	therefore	therefore	ADV
bptjm-66	387	2	,	,	PUNCT
bptjm-66	387	3	even	even	ADV
bptjm-66	387	4	in	in	ADP
bptjm-66	387	5	different	different	ADJ
bptjm-66	387	6	contexts	context	NOUN
bptjm-66	387	7	regardless	regardless	ADV
bptjm-66	387	8	of	of	ADP
bptjm-66	387	9	the	the	DET
bptjm-66	387	10	causation	causation	NOUN
bptjm-66	387	11	of	of	ADP
bptjm-66	387	12	said	say	VERB
bptjm-66	387	13	neuropathic	neuropathic	ADJ
bptjm-66	387	14	pain	pain	NOUN
bptjm-66	387	15	,	,	PUNCT
bptjm-66	387	16	capsaicin	capsaicin	PROPN
bptjm-66	387	17	appears	appear	VERB
bptjm-66	387	18	to	to	PART
bptjm-66	387	19	be	be	AUX
bptjm-66	387	20	a	a	DET
bptjm-66	387	21	versatile	versatile	ADJ
bptjm-66	387	22	remedy	remedy	NOUN
bptjm-66	387	23	.	.	PUNCT
bptjm-66	388	1	a	a	DET
bptjm-66	388	2	randomized	randomized	ADJ
bptjm-66	388	3	clinical	clinical	ADJ
bptjm-66	388	4	trial	trial	NOUN
bptjm-66	388	5	involving	involve	VERB
bptjm-66	388	6	the	the	DET
bptjm-66	388	7	application	application	NOUN
bptjm-66	388	8	of	of	ADP
bptjm-66	388	9	ngx-4010	ngx-4010	NOUN
bptjm-66	388	10	,	,	PUNCT
bptjm-66	388	11	a	a	DET
bptjm-66	388	12	high	high	ADJ
bptjm-66	388	13	-	-	PUNCT
bptjm-66	388	14	concentration	concentration	NOUN
bptjm-66	388	15	capsaicin	capsaicin	NOUN
bptjm-66	388	16	patch	patch	NOUN
bptjm-66	388	17	,	,	PUNCT
bptjm-66	388	18	to	to	PART
bptjm-66	388	19	treat	treat	VERB
bptjm-66	388	20	painful	painful	ADJ
bptjm-66	388	21	hiv	hiv	NOUN
bptjm-66	388	22	-	-	PUNCT
bptjm-66	388	23	associated	associate	VERB
bptjm-66	388	24	neuropathy	neuropathy	ADJ
bptjm-66	388	25	areas	area	NOUN
bptjm-66	388	26	was	be	AUX
bptjm-66	388	27	conducive	conducive	ADJ
bptjm-66	388	28	to	to	ADP
bptjm-66	388	29	a	a	DET
bptjm-66	388	30	decrease	decrease	NOUN
bptjm-66	388	31	in	in	ADP
bptjm-66	388	32	the	the	DET
bptjm-66	388	33	average	average	ADJ
bptjm-66	388	34	pain	pain	NOUN
bptjm-66	388	35	felt	feel	VERB
bptjm-66	388	36	by	by	ADP
bptjm-66	388	37	participants	participant	NOUN
bptjm-66	388	38	(	(	PUNCT
bptjm-66	388	39	n=422)63	n=422)63	PROPN
bptjm-66	388	40	.	.	PUNCT
bptjm-66	389	1	the	the	DET
bptjm-66	389	2	study	study	NOUN
bptjm-66	389	3	involved	involve	VERB
bptjm-66	389	4	four	four	NUM
bptjm-66	389	5	groups	group	NOUN
bptjm-66	389	6	:	:	PUNCT
bptjm-66	389	7	ngx-4010	ngx-4010	NOUN
bptjm-66	389	8	,	,	PUNCT
bptjm-66	389	9	60	60	NUM
bptjm-66	389	10	berkeley	berkeley	PROPN
bptjm-66	389	11	pharma	pharma	PROPN
bptjm-66	389	12	tech	tech	NOUN
bptjm-66	389	13	journal	journal	NOUN
bptjm-66	389	14	of	of	ADP
bptjm-66	389	15	medicine	medicine	NOUN
bptjm-66	389	16	|	|	ADV
bptjm-66	389	17	27	27	NUM
bptjm-66	389	18	minutes	minute	NOUN
bptjm-66	389	19	(	(	PUNCT
bptjm-66	389	20	60	60	NUM
bptjm-66	389	21	min	min	NOUN
bptjm-66	389	22	of	of	ADP
bptjm-66	389	23	high	high	ADJ
bptjm-66	389	24	concentration	concentration	NOUN
bptjm-66	389	25	capsaicin	capsaicin	NOUN
bptjm-66	389	26	640	640	NUM
bptjm-66	389	27	mcg	mcg	NOUN
bptjm-66	389	28	/	/	SYM
bptjm-66	389	29	cm^2	cm^2	NOUN
bptjm-66	389	30	)	)	PUNCT
bptjm-66	389	31	,	,	PUNCT
bptjm-66	389	32	control	control	NOUN
bptjm-66	389	33	group	group	NOUN
bptjm-66	389	34	,	,	PUNCT
bptjm-66	389	35	60	60	NUM
bptjm-66	389	36	minutes	minute	NOUN
bptjm-66	389	37	(	(	PUNCT
bptjm-66	389	38	60	60	NUM
bptjm-66	389	39	min	min	NOUN
bptjm-66	389	40	of	of	ADP
bptjm-66	389	41	low	low	ADJ
bptjm-66	389	42	concentration	concentration	NOUN
bptjm-66	389	43	capsaicin	capsaicin	NOUN
bptjm-66	389	44	3.2	3.2	NUM
bptjm-66	389	45	mcg	mcg	PROPN
bptjm-66	389	46	/	/	SYM
bptjm-66	389	47	cm^2	cm^2	NOUN
bptjm-66	389	48	)	)	PUNCT
bptjm-66	389	49	,	,	PUNCT
bptjm-66	389	50	ngx-4010	ngx-4010	NOUN
bptjm-66	389	51	,	,	PUNCT
bptjm-66	389	52	30	30	NUM
bptjm-66	389	53	minutes	minute	NOUN
bptjm-66	389	54	(	(	PUNCT
bptjm-66	389	55	30	30	NUM
bptjm-66	389	56	min	min	NOUN
bptjm-66	389	57	of	of	ADP
bptjm-66	389	58	high	high	ADJ
bptjm-66	389	59	concentration	concentration	NOUN
bptjm-66	389	60	capsaicin	capsaicin	NOUN
bptjm-66	389	61	650	650	NUM
bptjm-66	389	62	mcg	mcg	PROPN
bptjm-66	389	63	/	/	SYM
bptjm-66	389	64	cm^2	cm^2	NOUN
bptjm-66	389	65	)	)	PUNCT
bptjm-66	389	66	,	,	PUNCT
bptjm-66	389	67	control	control	NOUN
bptjm-66	389	68	group	group	NOUN
bptjm-66	389	69	,	,	PUNCT
bptjm-66	389	70	30	30	NUM
bptjm-66	389	71	minutes	minute	NOUN
bptjm-66	389	72	(	(	PUNCT
bptjm-66	389	73	30	30	NUM
bptjm-66	389	74	min	min	NOUN
bptjm-66	389	75	of	of	ADP
bptjm-66	389	76	low	low	ADJ
bptjm-66	389	77	concentration	concentration	NOUN
bptjm-66	389	78	capsaicin	capsaicin	NOUN
bptjm-66	389	79	3.2	3.2	NUM
bptjm-66	389	80	mcg	mcg	PROPN
bptjm-66	389	81	/	/	SYM
bptjm-66	389	82	cm^2	cm^2	NOUN
bptjm-66	389	83	)	)	PUNCT
bptjm-66	389	84	.	.	PUNCT
bptjm-66	390	1	the	the	DET
bptjm-66	390	2	change	change	NOUN
bptjm-66	390	3	in	in	ADP
bptjm-66	390	4	mean	mean	NOUN
bptjm-66	390	5	for	for	ADP
bptjm-66	390	6	the	the	DET
bptjm-66	390	7	pain	pain	NOUN
bptjm-66	390	8	score	score	NOUN
bptjm-66	390	9	between	between	ADP
bptjm-66	390	10	weeks	week	NOUN
bptjm-66	390	11	2	2	NUM
bptjm-66	390	12	-	-	SYM
bptjm-66	390	13	12	12	NUM
bptjm-66	390	14	of	of	ADP
bptjm-66	390	15	the	the	DET
bptjm-66	390	16	study	study	NOUN
bptjm-66	390	17	period	period	NOUN
bptjm-66	390	18	on	on	ADP
bptjm-66	390	19	a	a	DET
bptjm-66	390	20	scale	scale	NOUN
bptjm-66	390	21	from	from	ADP
bptjm-66	390	22	0	0	NUM
bptjm-66	390	23	-	-	SYM
bptjm-66	390	24	10	10	NUM
bptjm-66	390	25	(	(	PUNCT
bptjm-66	390	26	0	0	NUM
bptjm-66	390	27	=	=	SYM
bptjm-66	390	28	no	no	DET
bptjm-66	390	29	pain	pain	NOUN
bptjm-66	390	30	,	,	PUNCT
bptjm-66	390	31	10	10	NUM
bptjm-66	390	32	=	=	SYM
bptjm-66	390	33	worst	bad	ADJ
bptjm-66	390	34	pain	pain	NOUN
bptjm-66	390	35	)	)	PUNCT
bptjm-66	390	36	for	for	ADP
bptjm-66	390	37	the	the	DET
bptjm-66	390	38	above	above	ADJ
bptjm-66	390	39	groups	group	NOUN
bptjm-66	390	40	listed	list	VERB
bptjm-66	390	41	were	be	AUX
bptjm-66	390	42	-32.8	-32.8	NOUN
bptjm-66	390	43	,	,	PUNCT
bptjm-66	390	44	-30.0	-30.0	NOUN
bptjm-66	390	45	,	,	PUNCT
bptjm-66	390	46	-26.2	-26.2	PROPN
bptjm-66	390	47	,	,	PUNCT
bptjm-66	390	48	and	and	CCONJ
bptjm-66	390	49	-19.1	-19.1	PUNCT
bptjm-66	390	50	respectively	respectively	ADV
bptjm-66	390	51	.	.	PUNCT
bptjm-66	391	1	the	the	DET
bptjm-66	391	2	“	"	PUNCT
bptjm-66	391	3	ngx-4010	ngx-4010	NOUN
bptjm-66	391	4	,	,	PUNCT
bptjm-66	391	5	60	60	NUM
bptjm-66	391	6	minutes	minute	NOUN
bptjm-66	391	7	”	"	PUNCT
bptjm-66	391	8	group	group	NOUN
bptjm-66	391	9	exhibited	exhibit	VERB
bptjm-66	391	10	the	the	DET
bptjm-66	391	11	largest	large	ADJ
bptjm-66	391	12	reduction	reduction	NOUN
bptjm-66	391	13	in	in	ADP
bptjm-66	391	14	pain	pain	NOUN
bptjm-66	391	15	score	score	NOUN
bptjm-66	391	16	.	.	PUNCT
bptjm-66	392	1	this	this	PRON
bptjm-66	392	2	suggests	suggest	VERB
bptjm-66	392	3	that	that	SCONJ
bptjm-66	392	4	a	a	DET
bptjm-66	392	5	higher	high	ADJ
bptjm-66	392	6	concentration	concentration	NOUN
bptjm-66	392	7	of	of	ADP
bptjm-66	392	8	capsaicin	capsaicin	NOUN
bptjm-66	392	9	and	and	CCONJ
bptjm-66	392	10	a	a	DET
bptjm-66	392	11	longer	long	ADJ
bptjm-66	392	12	duration	duration	NOUN
bptjm-66	392	13	of	of	ADP
bptjm-66	392	14	application	application	NOUN
bptjm-66	392	15	is	be	AUX
bptjm-66	392	16	optimal	optimal	ADJ
bptjm-66	392	17	.	.	PUNCT
bptjm-66	393	1	another	another	DET
bptjm-66	393	2	common	common	ADJ
bptjm-66	393	3	analgesia	analgesia	NOUN
bptjm-66	393	4	-	-	PUNCT
bptjm-66	393	5	induced	induce	VERB
bptjm-66	393	6	patch	patch	NOUN
bptjm-66	393	7	used	use	VERB
bptjm-66	393	8	to	to	PART
bptjm-66	393	9	treat	treat	VERB
bptjm-66	393	10	neuropathic	neuropathic	ADJ
bptjm-66	393	11	pain	pain	NOUN
bptjm-66	393	12	is	be	AUX
bptjm-66	393	13	through	through	ADP
bptjm-66	393	14	the	the	DET
bptjm-66	393	15	local	local	ADJ
bptjm-66	393	16	anesthetic	anesthetic	ADJ
bptjm-66	393	17	lidocaine64	lidocaine64	NOUN
bptjm-66	393	18	.	.	PUNCT
bptjm-66	394	1	frequently	frequently	ADV
bptjm-66	394	2	juxtaposed	juxtapose	VERB
bptjm-66	394	3	with	with	ADP
bptjm-66	394	4	capsaicin	capsaicin	PROPN
bptjm-66	394	5	,	,	PUNCT
bptjm-66	394	6	both	both	DET
bptjm-66	394	7	drugs	drug	NOUN
bptjm-66	394	8	are	be	AUX
bptjm-66	394	9	mediators	mediator	NOUN
bptjm-66	394	10	for	for	ADP
bptjm-66	394	11	neuropathy	neuropathy	ADJ
bptjm-66	394	12	,	,	PUNCT
bptjm-66	394	13	but	but	CCONJ
bptjm-66	394	14	should	should	AUX
bptjm-66	394	15	not	not	PART
bptjm-66	394	16	be	be	AUX
bptjm-66	394	17	used	use	VERB
bptjm-66	394	18	interchangeably	interchangeably	ADV
bptjm-66	394	19	.	.	PUNCT
bptjm-66	395	1	their	their	PRON
bptjm-66	395	2	mechanism	mechanism	NOUN
bptjm-66	395	3	of	of	ADP
bptjm-66	395	4	action	action	NOUN
bptjm-66	395	5	,	,	PUNCT
bptjm-66	395	6	situational	situational	ADJ
bptjm-66	395	7	application	application	NOUN
bptjm-66	395	8	,	,	PUNCT
bptjm-66	395	9	and	and	CCONJ
bptjm-66	395	10	analgesic	analgesic	ADJ
bptjm-66	395	11	effects	effect	NOUN
bptjm-66	395	12	differ	differ	VERB
bptjm-66	395	13	.	.	PUNCT
bptjm-66	396	1	lidocaine	lidocaine	PROPN
bptjm-66	396	2	works	work	VERB
bptjm-66	396	3	to	to	PART
bptjm-66	396	4	block	block	VERB
bptjm-66	396	5	nerve	nerve	NOUN
bptjm-66	396	6	signals	signal	NOUN
bptjm-66	396	7	in	in	ADP
bptjm-66	396	8	the	the	DET
bptjm-66	396	9	area	area	NOUN
bptjm-66	396	10	of	of	ADP
bptjm-66	396	11	application	application	NOUN
bptjm-66	396	12	by	by	ADP
bptjm-66	396	13	inhibiting	inhibit	VERB
bptjm-66	396	14	the	the	DET
bptjm-66	396	15	action	action	NOUN
bptjm-66	396	16	potentials	potential	NOUN
bptjm-66	396	17	occurring	occur	VERB
bptjm-66	396	18	between	between	ADP
bptjm-66	396	19	nerves	nerve	NOUN
bptjm-66	396	20	through	through	ADP
bptjm-66	396	21	interference	interference	NOUN
bptjm-66	396	22	with	with	ADP
bptjm-66	396	23	sodium	sodium	NOUN
bptjm-66	396	24	channels	channel	NOUN
bptjm-66	396	25	.	.	PUNCT
bptjm-66	397	1	it	it	PRON
bptjm-66	397	2	is	be	AUX
bptjm-66	397	3	mainly	mainly	ADV
bptjm-66	397	4	used	use	VERB
bptjm-66	397	5	in	in	ADP
bptjm-66	397	6	medical	medical	ADJ
bptjm-66	397	7	procedures	procedure	NOUN
bptjm-66	397	8	that	that	PRON
bptjm-66	397	9	require	require	VERB
bptjm-66	397	10	localized	localized	ADJ
bptjm-66	397	11	analgesia	analgesia	NOUN
bptjm-66	397	12	,	,	PUNCT
bptjm-66	397	13	resulting	result	VERB
bptjm-66	397	14	in	in	ADP
bptjm-66	397	15	a	a	DET
bptjm-66	397	16	numbing	numb	VERB
bptjm-66	397	17	sensation	sensation	NOUN
bptjm-66	397	18	in	in	ADP
bptjm-66	397	19	the	the	DET
bptjm-66	397	20	area	area	NOUN
bptjm-66	397	21	due	due	ADP
bptjm-66	397	22	to	to	ADP
bptjm-66	397	23	the	the	DET
bptjm-66	397	24	blockage	blockage	NOUN
bptjm-66	397	25	of	of	ADP
bptjm-66	397	26	transmission	transmission	NOUN
bptjm-66	397	27	signals	signal	NOUN
bptjm-66	397	28	.	.	PUNCT
bptjm-66	398	1	however	however	ADV
bptjm-66	398	2	,	,	PUNCT
bptjm-66	398	3	both	both	DET
bptjm-66	398	4	lidocaine	lidocaine	NOUN
bptjm-66	398	5	and	and	CCONJ
bptjm-66	398	6	capsaicin	capsaicin	NOUN
bptjm-66	398	7	are	be	AUX
bptjm-66	398	8	effective	effective	ADJ
bptjm-66	398	9	neuropathic	neuropathic	ADJ
bptjm-66	398	10	pain	pain	NOUN
bptjm-66	398	11	relievers	reliever	NOUN
bptjm-66	398	12	that	that	PRON
bptjm-66	398	13	produce	produce	VERB
bptjm-66	398	14	anti	anti	ADJ
bptjm-66	398	15	-	-	ADJ
bptjm-66	398	16	inflammatory	inflammatory	ADJ
bptjm-66	398	17	effects	effect	NOUN
bptjm-66	398	18	,	,	PUNCT
bptjm-66	398	19	it	it	PRON
bptjm-66	398	20	is	be	AUX
bptjm-66	398	21	believed	believe	VERB
bptjm-66	398	22	that	that	SCONJ
bptjm-66	398	23	lidocaine	lidocaine	NOUN
bptjm-66	398	24	is	be	AUX
bptjm-66	398	25	more	more	ADV
bptjm-66	398	26	effective	effective	ADJ
bptjm-66	398	27	short	short	ADJ
bptjm-66	398	28	term	term	NOUN
bptjm-66	398	29	like	like	ADP
bptjm-66	398	30	in	in	ADP
bptjm-66	398	31	cases	case	NOUN
bptjm-66	398	32	of	of	ADP
bptjm-66	398	33	dental	dental	ADJ
bptjm-66	398	34	procedures	procedure	NOUN
bptjm-66	398	35	or	or	CCONJ
bptjm-66	398	36	minor	minor	ADJ
bptjm-66	398	37	abrasions	abrasion	NOUN
bptjm-66	398	38	while	while	SCONJ
bptjm-66	398	39	capsaicin	capsaicin	NOUN
bptjm-66	398	40	is	be	AUX
bptjm-66	398	41	more	more	ADV
bptjm-66	398	42	effective	effective	ADJ
bptjm-66	398	43	long	long	ADJ
bptjm-66	398	44	term	term	NOUN
bptjm-66	398	45	involving	involve	VERB
bptjm-66	398	46	treatment	treatment	NOUN
bptjm-66	398	47	of	of	ADP
bptjm-66	398	48	allodynia	allodynia	NOUN
bptjm-66	398	49	and	and	CCONJ
bptjm-66	398	50	hyperalgesia	hyperalgesia	NOUN
bptjm-66	398	51	.	.	PUNCT
bptjm-66	399	1	a	a	DET
bptjm-66	399	2	double	double	ADJ
bptjm-66	399	3	-	-	PUNCT
bptjm-66	399	4	blinded	blind	VERB
bptjm-66	399	5	,	,	PUNCT
bptjm-66	399	6	placebo	placebo	NOUN
bptjm-66	399	7	-	-	PUNCT
bptjm-66	399	8	controlled	control	VERB
bptjm-66	399	9	,	,	PUNCT
bptjm-66	399	10	parallel	parallel	ADJ
bptjm-66	399	11	-	-	PUNCT
bptjm-66	399	12	group	group	NOUN
bptjm-66	399	13	study	study	NOUN
bptjm-66	399	14	was	be	AUX
bptjm-66	399	15	conducted	conduct	VERB
bptjm-66	399	16	to	to	PART
bptjm-66	399	17	observe	observe	VERB
bptjm-66	399	18	the	the	DET
bptjm-66	399	19	development	development	NOUN
bptjm-66	399	20	of	of	ADP
bptjm-66	399	21	adverse	adverse	ADJ
bptjm-66	399	22	effects	effect	NOUN
bptjm-66	399	23	in	in	ADP
bptjm-66	399	24	type	type	NOUN
bptjm-66	399	25	2	2	NUM
bptjm-66	399	26	diabetics	diabetic	NOUN
bptjm-66	399	27	experiencing	experience	VERB
bptjm-66	399	28	symptoms	symptom	NOUN
bptjm-66	399	29	of	of	ADP
bptjm-66	399	30	peripheral	peripheral	ADJ
bptjm-66	399	31	neuropathy	neuropathy	ADJ
bptjm-66	399	32	(	(	PUNCT
bptjm-66	399	33	pricking	prick	VERB
bptjm-66	399	34	sensations	sensation	NOUN
bptjm-66	399	35	,	,	PUNCT
bptjm-66	399	36	numbness	numbness	NOUN
bptjm-66	399	37	,	,	PUNCT
bptjm-66	399	38	burning	burning	NOUN
bptjm-66	399	39	,	,	PUNCT
bptjm-66	399	40	and	and	CCONJ
bptjm-66	399	41	aching	ache	VERB
bptjm-66	399	42	in	in	ADP
bptjm-66	399	43	feet	foot	NOUN
bptjm-66	399	44	)	)	PUNCT
bptjm-66	399	45	for	for	ADP
bptjm-66	399	46	more	more	ADJ
bptjm-66	399	47	than	than	ADP
bptjm-66	399	48	10	10	NUM
bptjm-66	399	49	years	year	NOUN
bptjm-66	399	50	.	.	PUNCT
bptjm-66	400	1	only	only	ADV
bptjm-66	400	2	males	male	NOUN
bptjm-66	400	3	ages	age	NOUN
bptjm-66	400	4	40	40	NUM
bptjm-66	400	5	-	-	SYM
bptjm-66	400	6	60	60	NUM
bptjm-66	400	7	were	be	AUX
bptjm-66	400	8	chosen	choose	VERB
bptjm-66	400	9	as	as	ADP
bptjm-66	400	10	participants	participant	NOUN
bptjm-66	400	11	for	for	ADP
bptjm-66	400	12	this	this	DET
bptjm-66	400	13	study	study	NOUN
bptjm-66	400	14	(	(	PUNCT
bptjm-66	400	15	n=273	n=273	NOUN
bptjm-66	400	16	)	)	PUNCT
bptjm-66	400	17	to	to	PART
bptjm-66	400	18	avoid	avoid	VERB
bptjm-66	400	19	possible	possible	ADJ
bptjm-66	400	20	hormonal	hormonal	ADJ
bptjm-66	400	21	issues	issue	NOUN
bptjm-66	400	22	as	as	ADP
bptjm-66	400	23	variables	variable	NOUN
bptjm-66	400	24	.	.	PUNCT
bptjm-66	401	1	patients	patient	NOUN
bptjm-66	401	2	scored	score	VERB
bptjm-66	401	3	from	from	ADP
bptjm-66	401	4	0	0	NUM
bptjm-66	401	5	-	-	SYM
bptjm-66	401	6	10	10	NUM
bptjm-66	401	7	(	(	PUNCT
bptjm-66	401	8	0	0	NUM
bptjm-66	401	9	=	=	SYM
bptjm-66	401	10	no	no	DET
bptjm-66	401	11	pain	pain	NOUN
bptjm-66	401	12	,	,	PUNCT
bptjm-66	401	13	10	10	NUM
bptjm-66	401	14	=	=	SYM
bptjm-66	401	15	worst	bad	ADJ
bptjm-66	401	16	pain	pain	NOUN
bptjm-66	401	17	)	)	PUNCT
bptjm-66	401	18	.	.	PUNCT
bptjm-66	402	1	the	the	DET
bptjm-66	402	2	study	study	NOUN
bptjm-66	402	3	groups	group	NOUN
bptjm-66	402	4	are	be	AUX
bptjm-66	402	5	as	as	SCONJ
bptjm-66	402	6	follows	follow	VERB
bptjm-66	402	7	:	:	PUNCT
bptjm-66	402	8	group	group	NOUN
bptjm-66	402	9	ll	ll	NOUN
bptjm-66	402	10	(	(	PUNCT
bptjm-66	402	11	5	5	NUM
bptjm-66	402	12	%	%	NOUN
bptjm-66	402	13	lidocaine	lidocaine	NOUN
bptjm-66	402	14	patch	patch	NOUN
bptjm-66	402	15	700	700	NUM
bptjm-66	402	16	mg	mg	NOUN
bptjm-66	402	17	lidocaine	lidocaine	NOUN
bptjm-66	402	18	for	for	ADP
bptjm-66	402	19	60	60	NUM
bptjm-66	402	20	min	min	NOUN
bptjm-66	402	21	)	)	PUNCT
bptjm-66	402	22	,	,	PUNCT
bptjm-66	402	23	group	group	NOUN
bptjm-66	402	24	lp	lp	NOUN
bptjm-66	402	25	(	(	PUNCT
bptjm-66	402	26	placebo	placebo	NOUN
bptjm-66	402	27	patch	patch	NOUN
bptjm-66	402	28	for	for	ADP
bptjm-66	402	29	60	60	NUM
bptjm-66	402	30	min	min	NOUN
bptjm-66	402	31	)	)	PUNCT
bptjm-66	402	32	,	,	PUNCT
bptjm-66	402	33	and	and	CCONJ
bptjm-66	402	34	group	group	NOUN
bptjm-66	402	35	lc	lc	PROPN
bptjm-66	402	36	(	(	PUNCT
bptjm-66	402	37	8	8	NUM
bptjm-66	402	38	%	%	NOUN
bptjm-66	402	39	capsaicin	capsaicin	NOUN
bptjm-66	402	40	patch	patch	VERB
bptjm-66	402	41	179	179	NUM
bptjm-66	402	42	mg	mg	NOUN
bptjm-66	402	43	for	for	ADP
bptjm-66	402	44	60	60	NUM
bptjm-66	402	45	min	min	NOUN
bptjm-66	402	46	)	)	PUNCT
bptjm-66	402	47	.	.	PUNCT
bptjm-66	403	1	after	after	ADP
bptjm-66	403	2	24	24	NUM
bptjm-66	403	3	weeks	week	NOUN
bptjm-66	403	4	,	,	PUNCT
bptjm-66	403	5	group	group	NOUN
bptjm-66	403	6	lc	lc	PROPN
bptjm-66	403	7	displayed	display	VERB
bptjm-66	403	8	significantly	significantly	ADV
bptjm-66	403	9	reduced	reduce	VERB
bptjm-66	403	10	pain	pain	NOUN
bptjm-66	403	11	scores	score	NOUN
bptjm-66	403	12	compared	compare	VERB
bptjm-66	403	13	to	to	ADP
bptjm-66	403	14	group	group	PROPN
bptjm-66	403	15	lp	lp	PROPN
bptjm-66	403	16	.	.	PUNCT
bptjm-66	404	1	the	the	DET
bptjm-66	404	2	average	average	ADJ
bptjm-66	404	3	pain	pain	NOUN
bptjm-66	404	4	scores	score	NOUN
bptjm-66	404	5	for	for	ADP
bptjm-66	404	6	the	the	DET
bptjm-66	404	7	groups	group	NOUN
bptjm-66	404	8	are	be	AUX
bptjm-66	404	9	as	as	SCONJ
bptjm-66	404	10	follows	follow	VERB
bptjm-66	404	11	:	:	PUNCT
bptjm-66	404	12	ll	ll	AUX
bptjm-66	404	13	:	:	PUNCT
bptjm-66	404	14	6.4	6.4	NUM
bptjm-66	404	15	to	to	ADP
bptjm-66	404	16	4.9	4.9	NUM
bptjm-66	404	17	,	,	PUNCT
bptjm-66	404	18	lp	lp	ADJ
bptjm-66	404	19	:	:	PUNCT
bptjm-66	404	20	6.1	6.1	NUM
bptjm-66	404	21	to	to	PART
bptjm-66	404	22	5.7	5.7	NUM
bptjm-66	404	23	,	,	PUNCT
bptjm-66	404	24	lc	lc	NOUN
bptjm-66	404	25	:	:	PUNCT
bptjm-66	404	26	6.7	6.7	NUM
bptjm-66	404	27	to	to	PART
bptjm-66	404	28	3.6	3.6	NUM
bptjm-66	404	29	.	.	PUNCT
bptjm-66	405	1	berkeley	berkeley	PROPN
bptjm-66	405	2	pharma	pharma	PROPN
bptjm-66	405	3	tech	tech	PROPN
bptjm-66	405	4	journal	journal	NOUN
bptjm-66	405	5	of	of	ADP
bptjm-66	405	6	medicine	medicine	NOUN
bptjm-66	405	7	|	|	ADV
bptjm-66	405	8	28	28	NUM
bptjm-66	405	9	group	group	NOUN
bptjm-66	405	10	average	average	ADJ
bptjm-66	405	11	satisfaction	satisfaction	NOUN
bptjm-66	405	12	scores	score	NOUN
bptjm-66	405	13	(	(	PUNCT
bptjm-66	405	14	0	0	NUM
bptjm-66	405	15	=	=	SYM
bptjm-66	405	16	poor	poor	ADJ
bptjm-66	405	17	,	,	PUNCT
bptjm-66	405	18	4	4	NUM
bptjm-66	405	19	=	=	SYM
bptjm-66	405	20	excellent	excellent	ADJ
bptjm-66	405	21	)	)	PUNCT
bptjm-66	405	22	are	be	AUX
bptjm-66	405	23	as	as	SCONJ
bptjm-66	405	24	follows	follow	VERB
bptjm-66	405	25	:	:	PUNCT
bptjm-66	405	26	ll	ll	AUX
bptjm-66	405	27	:	:	PUNCT
bptjm-66	405	28	2.1	2.1	NUM
bptjm-66	405	29	to	to	PART
bptjm-66	405	30	3.2	3.2	NUM
bptjm-66	405	31	,	,	PUNCT
bptjm-66	405	32	lp	lp	ADJ
bptjm-66	405	33	:	:	PUNCT
bptjm-66	405	34	2.2	2.2	NUM
bptjm-66	405	35	to	to	ADP
bptjm-66	405	36	2.5	2.5	NUM
bptjm-66	405	37	,	,	PUNCT
bptjm-66	405	38	lc	lc	PROPN
bptjm-66	405	39	:	:	PUNCT
bptjm-66	405	40	2.0	2.0	NUM
bptjm-66	405	41	to	to	PART
bptjm-66	405	42	4.2	4.2	NUM
bptjm-66	405	43	.	.	PUNCT
bptjm-66	406	1	showing	show	VERB
bptjm-66	406	2	higher	high	ADJ
bptjm-66	406	3	and	and	CCONJ
bptjm-66	406	4	improved	improved	ADJ
bptjm-66	406	5	scores	score	NOUN
bptjm-66	406	6	than	than	ADP
bptjm-66	406	7	group	group	NOUN
bptjm-66	406	8	ll	ll	NOUN
bptjm-66	406	9	in	in	ADP
bptjm-66	406	10	both	both	CCONJ
bptjm-66	406	11	average	average	ADJ
bptjm-66	406	12	pain	pain	NOUN
bptjm-66	406	13	score	score	NOUN
bptjm-66	406	14	and	and	CCONJ
bptjm-66	406	15	satisfaction	satisfaction	NOUN
bptjm-66	406	16	score	score	NOUN
bptjm-66	406	17	,	,	PUNCT
bptjm-66	406	18	group	group	NOUN
bptjm-66	406	19	lc	lc	PROPN
bptjm-66	406	20	demonstrates	demonstrate	VERB
bptjm-66	406	21	a	a	DET
bptjm-66	406	22	more	more	ADV
bptjm-66	406	23	potent	potent	ADJ
bptjm-66	406	24	analgesic	analgesic	ADJ
bptjm-66	406	25	effect	effect	NOUN
bptjm-66	406	26	.	.	PUNCT
bptjm-66	407	1	5	5	X
bptjm-66	407	2	.	.	X
bptjm-66	407	3	future	future	ADJ
bptjm-66	407	4	direction	direction	NOUN
bptjm-66	407	5	/	/	SYM
bptjm-66	407	6	implications	implication	NOUN
bptjm-66	407	7	the	the	DET
bptjm-66	407	8	emergence	emergence	NOUN
bptjm-66	407	9	of	of	ADP
bptjm-66	407	10	nanotechnology	nanotechnology	NOUN
bptjm-66	407	11	,	,	PUNCT
bptjm-66	407	12	external	external	ADJ
bptjm-66	407	13	modalities	modality	NOUN
bptjm-66	407	14	,	,	PUNCT
bptjm-66	407	15	and	and	CCONJ
bptjm-66	407	16	passive	passive	ADJ
bptjm-66	407	17	treatments	treatment	NOUN
bptjm-66	407	18	has	have	AUX
bptjm-66	407	19	changed	change	VERB
bptjm-66	407	20	the	the	DET
bptjm-66	407	21	future	future	NOUN
bptjm-66	407	22	of	of	ADP
bptjm-66	407	23	the	the	DET
bptjm-66	407	24	pain	pain	NOUN
bptjm-66	407	25	management	management	NOUN
bptjm-66	407	26	industry	industry	NOUN
bptjm-66	407	27	.	.	PUNCT
bptjm-66	408	1	with	with	ADP
bptjm-66	408	2	the	the	DET
bptjm-66	408	3	status	status	NOUN
bptjm-66	408	4	of	of	ADP
bptjm-66	408	5	pain	pain	NOUN
bptjm-66	408	6	alleviation	alleviation	NOUN
bptjm-66	408	7	not	not	PART
bptjm-66	408	8	curing	cure	VERB
bptjm-66	408	9	or	or	CCONJ
bptjm-66	408	10	fully	fully	ADV
bptjm-66	408	11	treating	treat	VERB
bptjm-66	408	12	the	the	DET
bptjm-66	408	13	problem	problem	NOUN
bptjm-66	408	14	,	,	PUNCT
bptjm-66	408	15	these	these	DET
bptjm-66	408	16	new	new	ADJ
bptjm-66	408	17	developing	develop	VERB
bptjm-66	408	18	treatments	treatment	NOUN
bptjm-66	408	19	show	show	VERB
bptjm-66	408	20	promising	promise	VERB
bptjm-66	408	21	outcomes	outcome	NOUN
bptjm-66	408	22	.	.	PUNCT
bptjm-66	409	1	they	they	PRON
bptjm-66	409	2	have	have	AUX
bptjm-66	409	3	shown	show	VERB
bptjm-66	409	4	fewer	few	ADJ
bptjm-66	409	5	side	side	ADJ
bptjm-66	409	6	effects	effect	NOUN
bptjm-66	409	7	and	and	CCONJ
bptjm-66	409	8	complications	complication	NOUN
bptjm-66	409	9	because	because	SCONJ
bptjm-66	409	10	of	of	ADP
bptjm-66	409	11	their	their	PRON
bptjm-66	409	12	external	external	ADJ
bptjm-66	409	13	and	and	CCONJ
bptjm-66	409	14	non	non	ADJ
bptjm-66	409	15	-	-	ADJ
bptjm-66	409	16	invasive	invasive	ADJ
bptjm-66	409	17	nature	nature	NOUN
bptjm-66	409	18	.	.	PUNCT
bptjm-66	410	1	for	for	ADP
bptjm-66	410	2	the	the	DET
bptjm-66	410	3	side	side	NOUN
bptjm-66	410	4	effects	effect	NOUN
bptjm-66	410	5	,	,	PUNCT
bptjm-66	410	6	they	they	PRON
bptjm-66	410	7	also	also	ADV
bptjm-66	410	8	showed	show	VERB
bptjm-66	410	9	no	no	DET
bptjm-66	410	10	addiction	addiction	NOUN
bptjm-66	410	11	,	,	PUNCT
bptjm-66	410	12	respiratory	respiratory	ADJ
bptjm-66	410	13	depression	depression	NOUN
bptjm-66	410	14	,	,	PUNCT
bptjm-66	410	15	and	and	CCONJ
bptjm-66	410	16	irregular	irregular	ADJ
bptjm-66	410	17	bowel	bowel	NOUN
bptjm-66	410	18	movements	movement	NOUN
bptjm-66	410	19	that	that	PRON
bptjm-66	410	20	are	be	AUX
bptjm-66	410	21	common	common	ADJ
bptjm-66	410	22	in	in	ADP
bptjm-66	410	23	the	the	DET
bptjm-66	410	24	current	current	ADJ
bptjm-66	410	25	treatments	treatment	NOUN
bptjm-66	410	26	such	such	ADJ
bptjm-66	410	27	as	as	ADP
bptjm-66	410	28	opioids	opioid	NOUN
bptjm-66	410	29	.	.	PUNCT
bptjm-66	411	1	in	in	ADP
bptjm-66	411	2	addition	addition	NOUN
bptjm-66	411	3	,	,	PUNCT
bptjm-66	411	4	the	the	DET
bptjm-66	411	5	style	style	NOUN
bptjm-66	411	6	of	of	ADP
bptjm-66	411	7	these	these	DET
bptjm-66	411	8	procedures	procedure	NOUN
bptjm-66	411	9	has	have	AUX
bptjm-66	411	10	been	be	AUX
bptjm-66	411	11	demonstrated	demonstrate	VERB
bptjm-66	411	12	to	to	PART
bptjm-66	411	13	be	be	AUX
bptjm-66	411	14	more	more	ADJ
bptjm-66	411	15	cost	cost	NOUN
bptjm-66	411	16	-	-	PUNCT
bptjm-66	411	17	effective	effective	ADJ
bptjm-66	411	18	when	when	SCONJ
bptjm-66	411	19	compared	compare	VERB
bptjm-66	411	20	to	to	ADP
bptjm-66	411	21	surgical	surgical	ADJ
bptjm-66	411	22	procedures	procedure	NOUN
bptjm-66	411	23	and	and	CCONJ
bptjm-66	411	24	the	the	DET
bptjm-66	411	25	repetitive	repetitive	ADJ
bptjm-66	411	26	prescriptions	prescription	NOUN
bptjm-66	411	27	of	of	ADP
bptjm-66	411	28	ongoing	ongoing	ADJ
bptjm-66	411	29	pain	pain	NOUN
bptjm-66	411	30	medicine	medicine	NOUN
bptjm-66	411	31	.	.	PUNCT
bptjm-66	412	1	even	even	ADV
bptjm-66	412	2	with	with	ADP
bptjm-66	412	3	these	these	DET
bptjm-66	412	4	advantages	advantage	NOUN
bptjm-66	412	5	of	of	ADP
bptjm-66	412	6	the	the	DET
bptjm-66	412	7	treatments	treatment	NOUN
bptjm-66	412	8	,	,	PUNCT
bptjm-66	412	9	there	there	PRON
bptjm-66	412	10	still	still	ADV
bptjm-66	412	11	needs	need	VERB
bptjm-66	412	12	to	to	PART
bptjm-66	412	13	be	be	AUX
bptjm-66	412	14	consideration	consideration	NOUN
bptjm-66	412	15	that	that	SCONJ
bptjm-66	412	16	these	these	PRON
bptjm-66	412	17	are	be	AUX
bptjm-66	412	18	developing	develop	VERB
bptjm-66	412	19	and	and	CCONJ
bptjm-66	412	20	still	still	ADV
bptjm-66	412	21	relatively	relatively	ADV
bptjm-66	412	22	new	new	ADJ
bptjm-66	412	23	with	with	ADP
bptjm-66	412	24	more	more	ADJ
bptjm-66	412	25	research	research	NOUN
bptjm-66	412	26	needing	need	VERB
bptjm-66	412	27	to	to	PART
bptjm-66	412	28	be	be	AUX
bptjm-66	412	29	done	do	VERB
bptjm-66	412	30	before	before	ADP
bptjm-66	412	31	widespread	widespread	ADJ
bptjm-66	412	32	usage	usage	NOUN
bptjm-66	412	33	.	.	PUNCT
bptjm-66	413	1	additionally	additionally	ADV
bptjm-66	413	2	,	,	PUNCT
bptjm-66	413	3	more	more	ADJ
bptjm-66	413	4	research	research	NOUN
bptjm-66	413	5	must	must	AUX
bptjm-66	413	6	be	be	AUX
bptjm-66	413	7	done	do	VERB
bptjm-66	413	8	to	to	PART
bptjm-66	413	9	make	make	VERB
bptjm-66	413	10	sure	sure	ADJ
bptjm-66	413	11	that	that	SCONJ
bptjm-66	413	12	each	each	DET
bptjm-66	413	13	method	method	NOUN
bptjm-66	413	14	would	would	AUX
bptjm-66	413	15	address	address	VERB
bptjm-66	413	16	the	the	DET
bptjm-66	413	17	root	root	NOUN
bptjm-66	413	18	causes	cause	NOUN
bptjm-66	413	19	of	of	ADP
bptjm-66	413	20	pain	pain	NOUN
bptjm-66	413	21	.	.	PUNCT
bptjm-66	414	1	despite	despite	SCONJ
bptjm-66	414	2	these	these	DET
bptjm-66	414	3	treatments	treatment	NOUN
bptjm-66	414	4	still	still	ADV
bptjm-66	414	5	being	be	AUX
bptjm-66	414	6	developed	develop	VERB
bptjm-66	414	7	,	,	PUNCT
bptjm-66	414	8	there	there	PRON
bptjm-66	414	9	would	would	AUX
bptjm-66	414	10	be	be	AUX
bptjm-66	414	11	ethical	ethical	ADJ
bptjm-66	414	12	considerations	consideration	NOUN
bptjm-66	414	13	to	to	PART
bptjm-66	414	14	address	address	VERB
bptjm-66	414	15	during	during	ADP
bptjm-66	414	16	their	their	PRON
bptjm-66	414	17	development	development	NOUN
bptjm-66	414	18	.	.	PUNCT
bptjm-66	415	1	those	those	DET
bptjm-66	415	2	ethical	ethical	ADJ
bptjm-66	415	3	considerations	consideration	NOUN
bptjm-66	415	4	include	include	VERB
bptjm-66	415	5	obtaining	obtain	VERB
bptjm-66	415	6	informed	informed	ADJ
bptjm-66	415	7	consent	consent	NOUN
bptjm-66	415	8	,	,	PUNCT
bptjm-66	415	9	ensuring	ensure	VERB
bptjm-66	415	10	patients	patient	NOUN
bptjm-66	415	11	understand	understand	VERB
bptjm-66	415	12	both	both	CCONJ
bptjm-66	415	13	the	the	DET
bptjm-66	415	14	benefits	benefit	NOUN
bptjm-66	415	15	and	and	CCONJ
bptjm-66	415	16	risks	risk	NOUN
bptjm-66	415	17	,	,	PUNCT
bptjm-66	415	18	guaranteeing	guarantee	VERB
bptjm-66	415	19	access	access	NOUN
bptjm-66	415	20	to	to	ADP
bptjm-66	415	21	treatment	treatment	NOUN
bptjm-66	415	22	without	without	ADP
bptjm-66	415	23	financial	financial	ADJ
bptjm-66	415	24	or	or	CCONJ
bptjm-66	415	25	insurance	insurance	NOUN
bptjm-66	415	26	-	-	PUNCT
bptjm-66	415	27	related	relate	VERB
bptjm-66	415	28	barriers	barrier	NOUN
bptjm-66	415	29	,	,	PUNCT
bptjm-66	415	30	and	and	CCONJ
bptjm-66	415	31	addressing	address	VERB
bptjm-66	415	32	conflicts	conflict	NOUN
bptjm-66	415	33	of	of	ADP
bptjm-66	415	34	interest	interest	NOUN
bptjm-66	415	35	among	among	ADP
bptjm-66	415	36	those	those	PRON
bptjm-66	415	37	promoting	promote	VERB
bptjm-66	415	38	the	the	DET
bptjm-66	415	39	treatments	treatment	NOUN
bptjm-66	415	40	.	.	PUNCT
bptjm-66	416	1	these	these	DET
bptjm-66	416	2	therapies	therapy	NOUN
bptjm-66	416	3	have	have	VERB
bptjm-66	416	4	currently	currently	ADV
bptjm-66	416	5	optimistic	optimistic	ADJ
bptjm-66	416	6	results	result	NOUN
bptjm-66	416	7	and	and	CCONJ
bptjm-66	416	8	will	will	AUX
bptjm-66	416	9	change	change	VERB
bptjm-66	416	10	the	the	DET
bptjm-66	416	11	future	future	NOUN
bptjm-66	416	12	of	of	ADP
bptjm-66	416	13	pain	pain	NOUN
bptjm-66	416	14	treatment	treatment	NOUN
bptjm-66	416	15	.	.	PUNCT
bptjm-66	417	1	6	6	X
bptjm-66	417	2	.	.	X
bptjm-66	417	3	conclusion	conclusion	NOUN
bptjm-66	417	4	as	as	SCONJ
bptjm-66	417	5	the	the	DET
bptjm-66	417	6	field	field	NOUN
bptjm-66	417	7	of	of	ADP
bptjm-66	417	8	biotechnology	biotechnology	NOUN
bptjm-66	417	9	continues	continue	VERB
bptjm-66	417	10	to	to	PART
bptjm-66	417	11	grow	grow	VERB
bptjm-66	417	12	,	,	PUNCT
bptjm-66	417	13	the	the	DET
bptjm-66	417	14	information	information	NOUN
bptjm-66	417	15	gained	gain	VERB
bptjm-66	417	16	here	here	ADV
bptjm-66	417	17	will	will	AUX
bptjm-66	417	18	help	help	VERB
bptjm-66	417	19	influence	influence	NOUN
bptjm-66	417	20	and	and	CCONJ
bptjm-66	417	21	promote	promote	VERB
bptjm-66	417	22	numerous	numerous	ADJ
bptjm-66	417	23	treatment	treatment	NOUN
bptjm-66	417	24	modalities	modality	NOUN
bptjm-66	417	25	that	that	PRON
bptjm-66	417	26	will	will	AUX
bptjm-66	417	27	help	help	VERB
bptjm-66	417	28	address	address	VERB
bptjm-66	417	29	chronic	chronic	ADJ
bptjm-66	417	30	pain	pain	NOUN
bptjm-66	417	31	in	in	ADP
bptjm-66	417	32	patients	patient	NOUN
bptjm-66	417	33	.	.	PUNCT
bptjm-66	418	1	these	these	DET
bptjm-66	418	2	modalities	modality	NOUN
bptjm-66	418	3	would	would	AUX
bptjm-66	418	4	offer	offer	VERB
bptjm-66	418	5	more	more	ADJ
bptjm-66	418	6	options	option	NOUN
bptjm-66	418	7	for	for	ADP
bptjm-66	418	8	the	the	DET
bptjm-66	418	9	large	large	ADJ
bptjm-66	418	10	population	population	NOUN
bptjm-66	418	11	of	of	ADP
bptjm-66	418	12	individuals	individual	NOUN
bptjm-66	418	13	who	who	PRON
bptjm-66	418	14	suffer	suffer	VERB
bptjm-66	418	15	from	from	ADP
bptjm-66	418	16	pain	pain	NOUN
bptjm-66	418	17	.	.	PUNCT
bptjm-66	419	1	in	in	ADP
bptjm-66	419	2	addition	addition	NOUN
bptjm-66	419	3	,	,	PUNCT
bptjm-66	419	4	they	they	PRON
bptjm-66	419	5	would	would	AUX
bptjm-66	419	6	be	be	AUX
bptjm-66	419	7	able	able	ADJ
bptjm-66	419	8	to	to	PART
bptjm-66	419	9	treat	treat	VERB
bptjm-66	419	10	chronic	chronic	ADJ
bptjm-66	419	11	pain	pain	NOUN
bptjm-66	419	12	and	and	CCONJ
bptjm-66	419	13	relieve	relieve	VERB
bptjm-66	419	14	it	it	PRON
bptjm-66	419	15	greater	great	ADJ
bptjm-66	419	16	berkeley	berkeley	PROPN
bptjm-66	419	17	pharma	pharma	PROPN
bptjm-66	419	18	tech	tech	NOUN
bptjm-66	419	19	journal	journal	NOUN
bptjm-66	419	20	of	of	ADP
bptjm-66	419	21	medicine	medicine	NOUN
bptjm-66	419	22	|	|	ADV
bptjm-66	419	23	29	29	NUM
bptjm-66	419	24	than	than	ADP
bptjm-66	419	25	the	the	DET
bptjm-66	419	26	ongoing	ongoing	ADJ
bptjm-66	419	27	treatments	treatment	NOUN
bptjm-66	419	28	.	.	PUNCT
bptjm-66	420	1	nanotechnology	nanotechnology	NOUN
bptjm-66	420	2	can	can	AUX
bptjm-66	420	3	effectively	effectively	ADV
bptjm-66	420	4	work	work	VERB
bptjm-66	420	5	with	with	ADP
bptjm-66	420	6	opioids	opioid	NOUN
bptjm-66	420	7	but	but	CCONJ
bptjm-66	420	8	enhance	enhance	VERB
bptjm-66	420	9	their	their	PRON
bptjm-66	420	10	safety	safety	NOUN
bptjm-66	420	11	profile	profile	NOUN
bptjm-66	420	12	with	with	ADP
bptjm-66	420	13	their	their	PRON
bptjm-66	420	14	controlled	control	VERB
bptjm-66	420	15	delivery	delivery	NOUN
bptjm-66	420	16	and	and	CCONJ
bptjm-66	420	17	high	high	ADJ
bptjm-66	420	18	specificity	specificity	NOUN
bptjm-66	420	19	.	.	PUNCT
bptjm-66	421	1	the	the	DET
bptjm-66	421	2	non	non	ADJ
bptjm-66	421	3	-	-	ADJ
bptjm-66	421	4	pharmaceutical	pharmaceutical	ADJ
bptjm-66	421	5	and	and	CCONJ
bptjm-66	421	6	external	external	ADJ
bptjm-66	421	7	treatments	treatment	NOUN
bptjm-66	421	8	such	such	ADJ
bptjm-66	421	9	as	as	ADP
bptjm-66	421	10	myofascial	myofascial	ADJ
bptjm-66	421	11	release	release	NOUN
bptjm-66	421	12	,	,	PUNCT
bptjm-66	421	13	tens	ten	NOUN
bptjm-66	421	14	,	,	PUNCT
bptjm-66	421	15	photobiomodulation	photobiomodulation	NOUN
bptjm-66	421	16	,	,	PUNCT
bptjm-66	421	17	and	and	CCONJ
bptjm-66	421	18	the	the	DET
bptjm-66	421	19	capsaicin	capsaicin	NOUN
bptjm-66	421	20	patch	patch	PROPN
bptjm-66	421	21	are	be	AUX
bptjm-66	421	22	non	non	ADJ
bptjm-66	421	23	-	-	ADJ
bptjm-66	421	24	invasive	invasive	ADJ
bptjm-66	421	25	and	and	CCONJ
bptjm-66	421	26	give	give	VERB
bptjm-66	421	27	little	little	ADJ
bptjm-66	421	28	to	to	ADP
bptjm-66	421	29	no	no	DET
bptjm-66	421	30	complications	complication	NOUN
bptjm-66	421	31	and	and	CCONJ
bptjm-66	421	32	chances	chance	NOUN
bptjm-66	421	33	of	of	ADP
bptjm-66	421	34	infections	infection	NOUN
bptjm-66	421	35	.	.	PUNCT
bptjm-66	422	1	although	although	SCONJ
bptjm-66	422	2	these	these	DET
bptjm-66	422	3	treatments	treatment	NOUN
bptjm-66	422	4	require	require	VERB
bptjm-66	422	5	further	further	ADJ
bptjm-66	422	6	research	research	NOUN
bptjm-66	422	7	,	,	PUNCT
bptjm-66	422	8	they	they	PRON
bptjm-66	422	9	have	have	AUX
bptjm-66	422	10	shown	show	VERB
bptjm-66	422	11	positive	positive	ADJ
bptjm-66	422	12	outcomes	outcome	NOUN
bptjm-66	422	13	with	with	ADP
bptjm-66	422	14	a	a	DET
bptjm-66	422	15	good	good	ADJ
bptjm-66	422	16	impact	impact	NOUN
bptjm-66	422	17	on	on	ADP
bptjm-66	422	18	the	the	DET
bptjm-66	422	19	future	future	NOUN
bptjm-66	422	20	of	of	ADP
bptjm-66	422	21	pain	pain	NOUN
bptjm-66	422	22	management	management	NOUN
bptjm-66	422	23	.	.	PUNCT
bptjm-66	423	1	furthermore	furthermore	ADV
bptjm-66	423	2	,	,	PUNCT
bptjm-66	423	3	pain	pain	NOUN
bptjm-66	423	4	treatments	treatment	NOUN
bptjm-66	423	5	will	will	AUX
bptjm-66	423	6	continue	continue	VERB
bptjm-66	423	7	to	to	PART
bptjm-66	423	8	advance	advance	VERB
bptjm-66	423	9	and	and	CCONJ
bptjm-66	423	10	evolve	evolve	VERB
bptjm-66	423	11	,	,	PUNCT
bptjm-66	423	12	expanding	expand	VERB
bptjm-66	423	13	the	the	DET
bptjm-66	423	14	range	range	NOUN
bptjm-66	423	15	of	of	ADP
bptjm-66	423	16	procedures	procedure	NOUN
bptjm-66	423	17	available	available	ADJ
bptjm-66	423	18	to	to	ADP
bptjm-66	423	19	patients	patient	NOUN
bptjm-66	423	20	,	,	PUNCT
bptjm-66	423	21	ultimately	ultimately	ADV
bptjm-66	423	22	improving	improve	VERB
bptjm-66	423	23	their	their	PRON
bptjm-66	423	24	wellbeing	wellbeing	NOUN
bptjm-66	423	25	.	.	PUNCT
bptjm-66	424	1	berkeley	berkeley	PROPN
bptjm-66	424	2	pharma	pharma	PROPN
bptjm-66	424	3	tech	tech	PROPN
bptjm-66	424	4	journal	journal	NOUN
bptjm-66	424	5	of	of	ADP
bptjm-66	424	6	medicine	medicine	NOUN
bptjm-66	424	7	|	|	ADV
bptjm-66	424	8	30	30	NUM
bptjm-66	424	9	references	reference	NOUN
bptjm-66	424	10	1	1	NUM
bptjm-66	424	11	.	.	PUNCT
bptjm-66	425	1	armstrong	armstrong	PROPN
bptjm-66	425	2	sa	sa	PROPN
bptjm-66	425	3	,	,	PUNCT
bptjm-66	425	4	herr	herr	PROPN
bptjm-66	425	5	mj	mj	PROPN
bptjm-66	425	6	.	.	PROPN
bptjm-66	425	7	physiology	physiology	NOUN
bptjm-66	425	8	,	,	PUNCT
bptjm-66	425	9	nociception	nociception	NOUN
bptjm-66	425	10	.	.	PUNCT
bptjm-66	426	1	statpearls	statpearls	PROPN
bptjm-66	426	2	.	.	PUNCT
bptjm-66	427	1	treasure	treasure	NOUN
bptjm-66	427	2	island	island	NOUN
bptjm-66	427	3	(	(	PUNCT
bptjm-66	427	4	fl	fl	PROPN
bptjm-66	427	5	):	):	PUNCT
bptjm-66	427	6	statpearls	statpearl	NOUN
bptjm-66	427	7	2	2	NUM
bptjm-66	427	8	.	.	PUNCT
bptjm-66	427	9	mitsikostas	mitsikostas	PROPN
bptjm-66	427	10	dd	dd	PROPN
bptjm-66	427	11	,	,	PUNCT
bptjm-66	427	12	moka	moka	NOUN
bptjm-66	427	13	e	e	PROPN
bptjm-66	427	14	,	,	PUNCT
bptjm-66	427	15	orrillo	orrillo	X
bptjm-66	427	16	e	e	X
bptjm-66	427	17	,	,	PUNCT
bptjm-66	427	18	et	et	PROPN
bptjm-66	427	19	al	al	PROPN
bptjm-66	427	20	.	.	PROPN
bptjm-66	427	21	neuropathic	neuropathic	ADJ
bptjm-66	427	22	pain	pain	NOUN
bptjm-66	427	23	in	in	ADP
bptjm-66	427	24	neurologic	neurologic	ADJ
bptjm-66	427	25	disorders	disorder	NOUN
bptjm-66	427	26	:	:	PUNCT
bptjm-66	427	27	a	a	DET
bptjm-66	427	28	narrative	narrative	NOUN
bptjm-66	427	29	review	review	NOUN
bptjm-66	427	30	.	.	PUNCT
bptjm-66	428	1	cureus	cureus	NOUN
bptjm-66	428	2	.	.	PUNCT
bptjm-66	429	1	2022;14(2	2022;14(2	NUM
bptjm-66	429	2	)	)	PUNCT
bptjm-66	429	3	.	.	PUNCT
bptjm-66	430	1	3	3	X
bptjm-66	430	2	.	.	X
bptjm-66	430	3	park	park	PROPN
bptjm-66	430	4	j	j	PROPN
bptjm-66	430	5	,	,	PUNCT
bptjm-66	430	6	park	park	PROPN
bptjm-66	430	7	h.	h.	PROPN
bptjm-66	430	8	botulinum	botulinum	PROPN
bptjm-66	430	9	toxin	toxin	PROPN
bptjm-66	430	10	for	for	ADP
bptjm-66	430	11	the	the	DET
bptjm-66	430	12	treatment	treatment	NOUN
bptjm-66	430	13	of	of	ADP
bptjm-66	430	14	neuropathic	neuropathic	ADJ
bptjm-66	430	15	pain	pain	NOUN
bptjm-66	430	16	.	.	PUNCT
bptjm-66	431	1	toxins	toxin	NOUN
bptjm-66	431	2	.	.	PUNCT
bptjm-66	432	1	2017;9(9):260	2017;9(9):260	NUM
bptjm-66	432	2	.	.	NOUN
bptjm-66	432	3	4	4	X
bptjm-66	432	4	.	.	X
bptjm-66	432	5	dydyk	dydyk	NOUN
bptjm-66	432	6	am	be	AUX
bptjm-66	432	7	,	,	PUNCT
bptjm-66	432	8	conermann	conermann	PROPN
bptjm-66	432	9	t.	t.	PROPN
bptjm-66	432	10	chronic	chronic	ADJ
bptjm-66	432	11	pain	pain	NOUN
bptjm-66	432	12	.	.	PUNCT
bptjm-66	433	1	statpearls	statpearl	NOUN
bptjm-66	433	2	.	.	PUNCT
bptjm-66	434	1	treasure	treasure	NOUN
bptjm-66	434	2	island	island	NOUN
bptjm-66	434	3	(	(	PUNCT
bptjm-66	434	4	fl	fl	PROPN
bptjm-66	434	5	):	):	PUNCT
bptjm-66	434	6	statpearls	statpearl	NOUN
bptjm-66	434	7	publishing	publishing	NOUN
bptjm-66	434	8	.	.	PUNCT
bptjm-66	435	1	5	5	X
bptjm-66	435	2	.	.	X
bptjm-66	435	3	linley	linley	PROPN
bptjm-66	435	4	je	je	PROPN
bptjm-66	435	5	,	,	PUNCT
bptjm-66	435	6	rose	rise	VERB
bptjm-66	435	7	k	k	PROPN
bptjm-66	435	8	,	,	PUNCT
bptjm-66	435	9	ooi	ooi	PROPN
bptjm-66	435	10	l	l	PROPN
bptjm-66	435	11	,	,	PUNCT
bptjm-66	435	12	gamper	gamper	ADJ
bptjm-66	435	13	n.	n.	NOUN
bptjm-66	435	14	understanding	understand	VERB
bptjm-66	435	15	inflammatory	inflammatory	ADJ
bptjm-66	435	16	pain	pain	NOUN
bptjm-66	435	17	:	:	PUNCT
bptjm-66	435	18	ion	ion	NOUN
bptjm-66	435	19	channels	channel	NOUN
bptjm-66	435	20	contributing	contribute	VERB
bptjm-66	435	21	to	to	AUX
bptjm-66	435	22	acute	acute	VERB
bptjm-66	435	23	and	and	CCONJ
bptjm-66	435	24	chronic	chronic	ADJ
bptjm-66	435	25	nociception	nociception	NOUN
bptjm-66	435	26	.	.	PUNCT
bptjm-66	436	1	pflügers	pflüger	NOUN
bptjm-66	436	2	archiv	archiv	PROPN
bptjm-66	436	3	european	european	PROPN
bptjm-66	436	4	journal	journal	PROPN
bptjm-66	436	5	of	of	ADP
bptjm-66	436	6	physiology	physiology	NOUN
bptjm-66	436	7	.	.	PUNCT
bptjm-66	437	1	2010;459(5):657	2010;459(5):657	NUM
bptjm-66	437	2	-	-	SYM
bptjm-66	437	3	669	669	NUM
bptjm-66	437	4	.	.	NOUN
bptjm-66	438	1	6	6	NUM
bptjm-66	438	2	.	.	X
bptjm-66	438	3	johnston	johnston	PROPN
bptjm-66	438	4	,	,	PUNCT
bptjm-66	438	5	c.	c.	PROPN
bptjm-66	438	6	h.	h.	PROPN
bptjm-66	438	7	,	,	PUNCT
bptjm-66	438	8	whittaker	whittaker	PROPN
bptjm-66	438	9	,	,	PUNCT
bptjm-66	438	10	a.	a.	PROPN
bptjm-66	438	11	l.	l.	PROPN
bptjm-66	438	12	,	,	PUNCT
bptjm-66	438	13	franklin	franklin	PROPN
bptjm-66	438	14	,	,	PUNCT
bptjm-66	438	15	s.	s.	PROPN
bptjm-66	438	16	h.	h.	PROPN
bptjm-66	438	17	,	,	PUNCT
bptjm-66	438	18	&	&	CCONJ
bptjm-66	438	19	hutchinson	hutchinson	PROPN
bptjm-66	438	20	,	,	PUNCT
bptjm-66	438	21	m.	m.	PROPN
bptjm-66	438	22	r.	r.	PROPN
bptjm-66	438	23	(	(	PUNCT
bptjm-66	438	24	2022	2022	NUM
bptjm-66	438	25	)	)	PUNCT
bptjm-66	438	26	.	.	PUNCT
bptjm-66	439	1	the	the	DET
bptjm-66	439	2	neuroimmune	neuroimmune	NOUN
bptjm-66	439	3	interface	interface	NOUN
bptjm-66	439	4	and	and	CCONJ
bptjm-66	439	5	chronic	chronic	ADJ
bptjm-66	439	6	pain	pain	NOUN
bptjm-66	439	7	through	through	ADP
bptjm-66	439	8	the	the	DET
bptjm-66	439	9	lens	lens	NOUN
bptjm-66	439	10	of	of	ADP
bptjm-66	439	11	production	production	NOUN
bptjm-66	439	12	animals	animal	NOUN
bptjm-66	439	13	.	.	PUNCT
bptjm-66	440	1	frontiers	frontier	NOUN
bptjm-66	440	2	in	in	ADP
bptjm-66	440	3	neuroscience	neuroscience	NOUN
bptjm-66	440	4	,	,	PUNCT
bptjm-66	440	5	16	16	NUM
bptjm-66	440	6	,	,	PUNCT
bptjm-66	440	7	887042	887042	NUM
bptjm-66	440	8	.	.	PUNCT
bptjm-66	441	1	7	7	X
bptjm-66	441	2	.	.	X
bptjm-66	441	3	el	el	PROPN
bptjm-66	441	4	-	-	PUNCT
bptjm-66	441	5	tallawy	tallawy	PROPN
bptjm-66	441	6	sn	sn	PROPN
bptjm-66	441	7	,	,	PUNCT
bptjm-66	441	8	nalamasu	nalamasu	NOUN
bptjm-66	441	9	r	r	NOUN
bptjm-66	441	10	,	,	PUNCT
bptjm-66	441	11	salem	salem	PROPN
bptjm-66	441	12	gi	gi	PROPN
bptjm-66	441	13	,	,	PUNCT
bptjm-66	441	14	lequang	lequang	PROPN
bptjm-66	441	15	jak	jak	PROPN
bptjm-66	441	16	,	,	PUNCT
bptjm-66	441	17	pergolizzi	pergolizzi	PROPN
bptjm-66	441	18	jv	jv	PROPN
bptjm-66	441	19	,	,	PUNCT
bptjm-66	441	20	christo	christo	PROPN
bptjm-66	442	1	pj	pj	PROPN
bptjm-66	442	2	.	.	PUNCT
bptjm-66	442	3	management	management	NOUN
bptjm-66	442	4	of	of	ADP
bptjm-66	442	5	musculoskeletal	musculoskeletal	ADJ
bptjm-66	442	6	pain	pain	NOUN
bptjm-66	442	7	:	:	PUNCT
bptjm-66	442	8	an	an	DET
bptjm-66	442	9	update	update	NOUN
bptjm-66	442	10	with	with	ADP
bptjm-66	442	11	emphasis	emphasis	NOUN
bptjm-66	442	12	on	on	ADP
bptjm-66	442	13	chronic	chronic	ADJ
bptjm-66	442	14	musculoskeletal	musculoskeletal	ADJ
bptjm-66	442	15	pain	pain	NOUN
bptjm-66	442	16	.	.	PUNCT
bptjm-66	443	1	pain	pain	NOUN
bptjm-66	443	2	and	and	CCONJ
bptjm-66	443	3	therapy	therapy	NOUN
bptjm-66	443	4	.	.	PUNCT
bptjm-66	444	1	2021;10(1	2021;10(1	NUM
bptjm-66	444	2	)	)	PUNCT
bptjm-66	444	3	.	.	PUNCT
bptjm-66	445	1	8	8	X
bptjm-66	445	2	.	.	X
bptjm-66	446	1	chen	chen	PROPN
bptjm-66	446	2	l	l	PROPN
bptjm-66	446	3	,	,	PUNCT
bptjm-66	446	4	deng	deng	PROPN
bptjm-66	446	5	h	h	PROPN
bptjm-66	446	6	,	,	PUNCT
bptjm-66	446	7	cui	cui	PROPN
bptjm-66	446	8	h	h	PROPN
bptjm-66	446	9	,	,	PUNCT
bptjm-66	446	10	et	et	PROPN
bptjm-66	446	11	al	al	PROPN
bptjm-66	446	12	.	.	PUNCT
bptjm-66	446	13	inflammatory	inflammatory	ADJ
bptjm-66	446	14	responses	response	NOUN
bptjm-66	446	15	and	and	CCONJ
bptjm-66	446	16	inflammation	inflammation	NOUN
bptjm-66	446	17	-	-	PUNCT
bptjm-66	446	18	associated	associate	VERB
bptjm-66	446	19	diseases	disease	NOUN
bptjm-66	446	20	in	in	ADP
bptjm-66	446	21	organs	organ	NOUN
bptjm-66	446	22	.	.	PUNCT
bptjm-66	447	1	oncotarget	oncotarget	NOUN
bptjm-66	447	2	.	.	PUNCT
bptjm-66	448	1	2017;9(6):7204	2017;9(6):7204	NUM
bptjm-66	448	2	-	-	SYM
bptjm-66	448	3	7218	7218	NUM
bptjm-66	448	4	.	.	PUNCT
bptjm-66	449	1	9	9	NUM
bptjm-66	449	2	.	.	X
bptjm-66	449	3	mee	mee	PROPN
bptjm-66	449	4	s	s	PROPN
bptjm-66	449	5	,	,	PUNCT
bptjm-66	449	6	bunney	bunney	PROPN
bptjm-66	449	7	bg	bg	PROPN
bptjm-66	449	8	,	,	PUNCT
bptjm-66	449	9	reist	reist	PROPN
bptjm-66	449	10	c	c	PROPN
bptjm-66	449	11	,	,	PUNCT
bptjm-66	449	12	potkin	potkin	PROPN
bptjm-66	449	13	sg	sg	PROPN
bptjm-66	449	14	,	,	PUNCT
bptjm-66	449	15	bunney	bunney	NOUN
bptjm-66	449	16	we	we	PRON
bptjm-66	449	17	.	.	PUNCT
bptjm-66	450	1	psychological	psychological	ADJ
bptjm-66	450	2	pain	pain	NOUN
bptjm-66	450	3	:	:	PUNCT
bptjm-66	450	4	a	a	DET
bptjm-66	450	5	review	review	NOUN
bptjm-66	450	6	of	of	ADP
bptjm-66	450	7	evidence	evidence	NOUN
bptjm-66	450	8	.	.	PUNCT
bptjm-66	451	1	journal	journal	NOUN
bptjm-66	451	2	of	of	ADP
bptjm-66	451	3	psychiatric	psychiatric	ADJ
bptjm-66	451	4	research	research	NOUN
bptjm-66	451	5	.	.	PUNCT
bptjm-66	452	1	2006;40(8):680	2006;40(8):680	NUM
bptjm-66	452	2	-	-	SYM
bptjm-66	452	3	690	690	NUM
bptjm-66	452	4	.	.	PUNCT
bptjm-66	453	1	10	10	NUM
bptjm-66	453	2	.	.	X
bptjm-66	454	1	yam	yam	NOUN
bptjm-66	454	2	m	m	PROPN
bptjm-66	454	3	,	,	PUNCT
bptjm-66	454	4	loh	loh	PROPN
bptjm-66	454	5	y	y	PROPN
bptjm-66	454	6	,	,	PUNCT
bptjm-66	454	7	tan	tan	PROPN
bptjm-66	454	8	c	c	NOUN
bptjm-66	454	9	,	,	PUNCT
bptjm-66	454	10	khadijah	khadijah	PROPN
bptjm-66	454	11	adam	adam	PROPN
bptjm-66	454	12	s	s	PROPN
bptjm-66	454	13	,	,	PUNCT
bptjm-66	454	14	abdul	abdul	PROPN
bptjm-66	454	15	manan	manan	PROPN
bptjm-66	454	16	n	n	PROPN
bptjm-66	454	17	,	,	PUNCT
bptjm-66	454	18	basir	basir	PROPN
bptjm-66	454	19	r.	r.	PROPN
bptjm-66	454	20	general	general	PROPN
bptjm-66	454	21	pathways	pathway	NOUN
bptjm-66	454	22	of	of	ADP
bptjm-66	454	23	pain	pain	NOUN
bptjm-66	454	24	sensation	sensation	NOUN
bptjm-66	454	25	and	and	CCONJ
bptjm-66	454	26	the	the	DET
bptjm-66	454	27	major	major	ADJ
bptjm-66	454	28	neurotransmitters	neurotransmitter	NOUN
bptjm-66	454	29	involved	involve	VERB
bptjm-66	454	30	in	in	ADP
bptjm-66	454	31	pain	pain	NOUN
bptjm-66	454	32	regulation	regulation	NOUN
bptjm-66	454	33	.	.	PUNCT
bptjm-66	455	1	international	international	ADJ
bptjm-66	455	2	journal	journal	NOUN
bptjm-66	455	3	of	of	ADP
bptjm-66	455	4	molecular	molecular	ADJ
bptjm-66	455	5	sciences	science	NOUN
bptjm-66	455	6	.	.	PUNCT
bptjm-66	456	1	2018;19(8):2164	2018;19(8):2164	NUM
bptjm-66	456	2	.	.	PUNCT
bptjm-66	457	1	11	11	NUM
bptjm-66	457	2	.	.	X
bptjm-66	458	1	jewett	jewett	PROPN
bptjm-66	458	2	be	be	AUX
bptjm-66	458	3	,	,	PUNCT
bptjm-66	458	4	thapa	thapa	PROPN
bptjm-66	458	5	b.	b.	PROPN
bptjm-66	458	6	physiology	physiology	PROPN
bptjm-66	458	7	,	,	PUNCT
bptjm-66	458	8	nmda	nmda	ADJ
bptjm-66	458	9	receptor	receptor	NOUN
bptjm-66	458	10	.	.	PUNCT
bptjm-66	459	1	statpearls	statpearls	PROPN
bptjm-66	459	2	.	.	PUNCT
bptjm-66	460	1	treasure	treasure	NOUN
bptjm-66	460	2	island	island	NOUN
bptjm-66	460	3	(	(	PUNCT
bptjm-66	460	4	fl	fl	PROPN
bptjm-66	460	5	):	):	PUNCT
bptjm-66	460	6	statpearls	statpearl	NOUN
bptjm-66	460	7	12	12	NUM
bptjm-66	460	8	.	.	PUNCT
bptjm-66	461	1	pathan	pathan	PROPN
bptjm-66	461	2	h	h	PROPN
bptjm-66	461	3	,	,	PUNCT
bptjm-66	461	4	williams	williams	PROPN
bptjm-66	461	5	j.	j.	PROPN
bptjm-66	461	6	basic	basic	ADJ
bptjm-66	461	7	opioid	opioid	PROPN
bptjm-66	461	8	pharmacology	pharmacology	NOUN
bptjm-66	461	9	:	:	PUNCT
bptjm-66	461	10	an	an	DET
bptjm-66	461	11	update	update	NOUN
bptjm-66	461	12	.	.	PUNCT
bptjm-66	462	1	british	british	ADJ
bptjm-66	462	2	journal	journal	PROPN
bptjm-66	462	3	of	of	ADP
bptjm-66	462	4	pain	pain	NOUN
bptjm-66	462	5	.	.	PUNCT
bptjm-66	463	1	2012;6(1):11	2012;6(1):11	NUM
bptjm-66	463	2	-	-	SYM
bptjm-66	463	3	16	16	NUM
bptjm-66	463	4	.	.	PUNCT
bptjm-66	464	1	13	13	NUM
bptjm-66	464	2	.	.	X
bptjm-66	464	3	de	de	PROPN
bptjm-66	464	4	tommaso	tommaso	PROPN
bptjm-66	464	5	m	m	PROPN
bptjm-66	464	6	,	,	PUNCT
bptjm-66	464	7	arendt	arendt	PROPN
bptjm-66	464	8	-	-	PUNCT
bptjm-66	464	9	nielsen	nielsen	PROPN
bptjm-66	464	10	l	l	PROPN
bptjm-66	464	11	,	,	PUNCT
bptjm-66	464	12	defrin	defrin	PROPN
bptjm-66	464	13	r	r	PROPN
bptjm-66	464	14	,	,	PUNCT
bptjm-66	464	15	kunz	kunz	PROPN
bptjm-66	464	16	m	m	PROPN
bptjm-66	464	17	,	,	PUNCT
bptjm-66	464	18	pickering	pickere	VERB
bptjm-66	464	19	g	g	PROPN
bptjm-66	464	20	,	,	PUNCT
bptjm-66	464	21	valeriani	valeriani	PROPN
bptjm-66	464	22	m.	m.	NOUN
bptjm-66	464	23	pain	pain	NOUN
bptjm-66	464	24	in	in	ADP
bptjm-66	464	25	neurodegenerative	neurodegenerative	ADJ
bptjm-66	464	26	disease	disease	NOUN
bptjm-66	464	27	:	:	PUNCT
bptjm-66	464	28	current	current	ADJ
bptjm-66	464	29	knowledge	knowledge	NOUN
bptjm-66	464	30	and	and	CCONJ
bptjm-66	464	31	future	future	ADJ
bptjm-66	464	32	perspectives	perspective	NOUN
bptjm-66	464	33	.	.	PUNCT
bptjm-66	465	1	behavioural	behavioural	ADJ
bptjm-66	465	2	neurology	neurology	NOUN
bptjm-66	465	3	.	.	PUNCT
bptjm-66	466	1	2016;2016:1	2016;2016:1	PROPN
bptjm-66	466	2	-	-	PROPN
bptjm-66	466	3	14	14	NUM
bptjm-66	466	4	.	.	PUNCT
bptjm-66	467	1	14	14	NUM
bptjm-66	467	2	.	.	PUNCT
bptjm-66	468	1	cattaneo	cattaneo	PROPN
bptjm-66	468	2	c	c	X
bptjm-66	468	3	,	,	PUNCT
bptjm-66	468	4	jost	jost	VERB
bptjm-66	468	5	wh	wh	PROPN
bptjm-66	468	6	.	.	PUNCT
bptjm-66	468	7	pain	pain	NOUN
bptjm-66	468	8	in	in	ADP
bptjm-66	468	9	parkinson	parkinson	NOUN
bptjm-66	468	10	’s	’s	PART
bptjm-66	468	11	disease	disease	NOUN
bptjm-66	468	12	:	:	PUNCT
bptjm-66	468	13	pathophysiology	pathophysiology	NOUN
bptjm-66	468	14	,	,	PUNCT
bptjm-66	468	15	classification	classification	NOUN
bptjm-66	468	16	and	and	CCONJ
bptjm-66	468	17	treatment	treatment	NOUN
bptjm-66	468	18	.	.	PUNCT
bptjm-66	469	1	journal	journal	NOUN
bptjm-66	469	2	of	of	ADP
bptjm-66	469	3	integrative	integrative	ADJ
bptjm-66	469	4	neuroscience	neuroscience	NOUN
bptjm-66	469	5	.	.	PUNCT
bptjm-66	470	1	2023;22(5):132	2023;22(5):132	NOUN
bptjm-66	470	2	.	.	PUNCT
bptjm-66	471	1	15	15	NUM
bptjm-66	471	2	.	.	PUNCT
bptjm-66	472	1	eivazi	eivazi	PROPN
bptjm-66	472	2	m	m	PROPN
bptjm-66	472	3	,	,	PUNCT
bptjm-66	472	4	abadi	abadi	PROPN
bptjm-66	472	5	l.	l.	PROPN
bptjm-66	472	6	low	low	PROPN
bptjm-66	472	7	back	back	ADJ
bptjm-66	472	8	pain	pain	NOUN
bptjm-66	472	9	in	in	ADP
bptjm-66	472	10	diabetes	diabetes	NOUN
bptjm-66	472	11	mellitus	mellitus	NOUN
bptjm-66	472	12	and	and	CCONJ
bptjm-66	472	13	importance	importance	NOUN
bptjm-66	472	14	of	of	ADP
bptjm-66	472	15	preventive	preventive	ADJ
bptjm-66	472	16	approach	approach	NOUN
bptjm-66	472	17	.	.	PUNCT
bptjm-66	473	1	health	health	NOUN
bptjm-66	473	2	promotion	promotion	NOUN
bptjm-66	473	3	perspectives	perspective	NOUN
bptjm-66	473	4	.	.	PUNCT
bptjm-66	474	1	2012;2(1):80	2012;2(1):80	X
bptjm-66	474	2	-	-	SYM
bptjm-66	474	3	88	88	NUM
bptjm-66	474	4	.	.	PUNCT
bptjm-66	475	1	16	16	NUM
bptjm-66	475	2	.	.	PUNCT
bptjm-66	476	1	rehling	rehle	VERB
bptjm-66	476	2	t	t	PROPN
bptjm-66	476	3	,	,	PUNCT
bptjm-66	476	4	bjørkman	bjørkman	NOUN
bptjm-66	476	5	asd	asd	PROPN
bptjm-66	476	6	,	,	PUNCT
bptjm-66	476	7	andersen	andersen	PROPN
bptjm-66	476	8	mb	mb	PROPN
bptjm-66	476	9	,	,	PUNCT
bptjm-66	476	10	ekholm	ekholm	ADJ
bptjm-66	476	11	o	o	NOUN
bptjm-66	476	12	,	,	PUNCT
bptjm-66	476	13	molsted	molste	VERB
bptjm-66	476	14	s.	s.	PROPN
bptjm-66	476	15	diabetes	diabetes	PROPN
bptjm-66	476	16	is	be	AUX
bptjm-66	476	17	associated	associate	VERB
bptjm-66	476	18	with	with	ADP
bptjm-66	476	19	musculoskeletal	musculoskeletal	ADJ
bptjm-66	476	20	pain	pain	NOUN
bptjm-66	476	21	,	,	PUNCT
bptjm-66	476	22	osteoarthritis	osteoarthritis	NOUN
bptjm-66	476	23	,	,	PUNCT
bptjm-66	476	24	osteoporosis	osteoporosis	NOUN
bptjm-66	476	25	,	,	PUNCT
bptjm-66	476	26	and	and	CCONJ
bptjm-66	476	27	rheumatoid	rheumatoid	VERB
bptjm-66	476	28	arthritis	arthritis	NOUN
bptjm-66	476	29	.	.	PUNCT
bptjm-66	477	1	journal	journal	PROPN
bptjm-66	477	2	of	of	ADP
bptjm-66	477	3	diabetes	diabetes	NOUN
bptjm-66	477	4	research	research	NOUN
bptjm-66	477	5	.	.	PUNCT
bptjm-66	478	1	2019;2019:1	2019;2019:1	NUM
bptjm-66	478	2	-	-	SYM
bptjm-66	478	3	6	6	NUM
bptjm-66	478	4	.	.	NOUN
bptjm-66	478	5	17	17	NUM
bptjm-66	478	6	.	.	PUNCT
bptjm-66	478	7	aldossari	aldossari	PROPN
bptjm-66	478	8	kk	kk	PROPN
bptjm-66	478	9	,	,	PUNCT
bptjm-66	478	10	shubair	shubair	NOUN
bptjm-66	478	11	mm	mm	PROPN
bptjm-66	478	12	,	,	PUNCT
bptjm-66	478	13	al	al	PROPN
bptjm-66	478	14	-	-	PUNCT
bptjm-66	478	15	zahrani	zahrani	PROPN
bptjm-66	478	16	j	j	PROPN
bptjm-66	478	17	,	,	PUNCT
bptjm-66	478	18	et	et	PROPN
bptjm-66	478	19	al	al	PROPN
bptjm-66	478	20	.	.	PROPN
bptjm-66	478	21	association	association	PROPN
bptjm-66	478	22	between	between	ADP
bptjm-66	478	23	chronic	chronic	ADJ
bptjm-66	478	24	pain	pain	NOUN
bptjm-66	478	25	and	and	CCONJ
bptjm-66	478	26	diabetes	diabetes	NOUN
bptjm-66	478	27	/	/	SYM
bptjm-66	478	28	prediabetes	prediabete	NOUN
bptjm-66	478	29	:	:	PUNCT
bptjm-66	478	30	a	a	DET
bptjm-66	478	31	population	population	NOUN
bptjm-66	478	32	-	-	PUNCT
bptjm-66	478	33	based	base	VERB
bptjm-66	478	34	cross	cross	ADJ
bptjm-66	478	35	-	-	ADJ
bptjm-66	478	36	sectional	sectional	ADJ
bptjm-66	478	37	survey	survey	NOUN
bptjm-66	478	38	in	in	ADP
bptjm-66	478	39	saudi	saudi	PROPN
bptjm-66	478	40	arabia	arabia	PROPN
bptjm-66	478	41	.	.	PUNCT
bptjm-66	479	1	pain	pain	PROPN
bptjm-66	479	2	berkeley	berkeley	PROPN
bptjm-66	479	3	pharma	pharma	PROPN
bptjm-66	479	4	tech	tech	NOUN
bptjm-66	479	5	journal	journal	NOUN
bptjm-66	479	6	of	of	ADP
bptjm-66	479	7	medicine	medicine	NOUN
bptjm-66	479	8	|	|	ADV
bptjm-66	479	9	31	31	NUM
bptjm-66	479	10	research	research	NOUN
bptjm-66	479	11	&	&	CCONJ
bptjm-66	479	12	management	management	NOUN
bptjm-66	479	13	.	.	PUNCT
bptjm-66	480	1	2020;2020:8239474	2020;2020:8239474	NUM
bptjm-66	480	2	.	.	PROPN
bptjm-66	481	1	18	18	NUM
bptjm-66	481	2	.	.	PUNCT
bptjm-66	482	1	filipponi	filipponi	PROPN
bptjm-66	482	2	c	c	PROPN
bptjm-66	482	3	,	,	PUNCT
bptjm-66	482	4	masiero	masiero	PROPN
bptjm-66	482	5	m	m	PROPN
bptjm-66	482	6	,	,	PUNCT
bptjm-66	482	7	pizzoli	pizzoli	PROPN
bptjm-66	482	8	sfm	sfm	PROPN
bptjm-66	482	9	,	,	PUNCT
bptjm-66	482	10	grasso	grasso	X
bptjm-66	482	11	r	r	NOUN
bptjm-66	482	12	,	,	PUNCT
bptjm-66	482	13	ferrucci	ferrucci	NOUN
bptjm-66	482	14	r	r	NOUN
bptjm-66	482	15	,	,	PUNCT
bptjm-66	482	16	pravettoni	pravettoni	PROPN
bptjm-66	482	17	g.	g.	PROPN
bptjm-66	483	1	a	a	DET
bptjm-66	483	2	comprehensive	comprehensive	ADJ
bptjm-66	483	3	analysis	analysis	NOUN
bptjm-66	483	4	of	of	ADP
bptjm-66	483	5	the	the	DET
bptjm-66	483	6	cancer	cancer	NOUN
bptjm-66	483	7	chronic	chronic	ADJ
bptjm-66	483	8	pain	pain	NOUN
bptjm-66	483	9	experience	experience	NOUN
bptjm-66	483	10	:	:	PUNCT
bptjm-66	483	11	a	a	DET
bptjm-66	483	12	narrative	narrative	NOUN
bptjm-66	483	13	review	review	NOUN
bptjm-66	483	14	.	.	PUNCT
bptjm-66	484	1	cancer	cancer	NOUN
bptjm-66	484	2	management	management	NOUN
bptjm-66	484	3	and	and	CCONJ
bptjm-66	484	4	research	research	NOUN
bptjm-66	484	5	.	.	PUNCT
bptjm-66	485	1	2022;volume	2022;volume	PROPN
bptjm-66	485	2	14:2173	14:2173	NUM
bptjm-66	485	3	-	-	SYM
bptjm-66	485	4	2184	2184	NUM
bptjm-66	485	5	.	.	PUNCT
bptjm-66	486	1	19	19	NUM
bptjm-66	486	2	.	.	PUNCT
bptjm-66	487	1	ghlichloo	ghlichloo	PROPN
bptjm-66	487	2	i	i	PRON
bptjm-66	487	3	,	,	PUNCT
bptjm-66	487	4	gerriets	gerriet	NOUN
bptjm-66	487	5	v.	v.	ADP
bptjm-66	487	6	nonsteroidal	nonsteroidal	NOUN
bptjm-66	487	7	anti	anti	ADJ
bptjm-66	487	8	-	-	ADJ
bptjm-66	487	9	inflammatory	inflammatory	ADJ
bptjm-66	487	10	drugs	drug	NOUN
bptjm-66	487	11	(	(	PUNCT
bptjm-66	487	12	nsaids	nsaid	NOUN
bptjm-66	487	13	)	)	PUNCT
bptjm-66	487	14	.	.	PUNCT
bptjm-66	488	1	statpearls	statpearls	PROPN
bptjm-66	488	2	.	.	PUNCT
bptjm-66	489	1	treasure	treasure	NOUN
bptjm-66	489	2	island	island	NOUN
bptjm-66	489	3	(	(	PUNCT
bptjm-66	489	4	fl	fl	NOUN
bptjm-66	489	5	)	)	PUNCT
bptjm-66	489	6	20	20	NUM
bptjm-66	489	7	.	.	PUNCT
bptjm-66	490	1	obata	obata	PROPN
bptjm-66	490	2	h.	h.	PROPN
bptjm-66	490	3	analgesic	analgesic	ADJ
bptjm-66	490	4	mechanisms	mechanism	NOUN
bptjm-66	490	5	of	of	ADP
bptjm-66	490	6	antidepressants	antidepressant	NOUN
bptjm-66	490	7	for	for	ADP
bptjm-66	490	8	neuropathic	neuropathic	ADJ
bptjm-66	490	9	pain	pain	NOUN
bptjm-66	490	10	.	.	PUNCT
bptjm-66	491	1	international	international	ADJ
bptjm-66	491	2	journal	journal	NOUN
bptjm-66	491	3	of	of	ADP
bptjm-66	491	4	molecular	molecular	ADJ
bptjm-66	491	5	sciences	science	NOUN
bptjm-66	491	6	.	.	PUNCT
bptjm-66	492	1	2017;18(11	2017;18(11	NUM
bptjm-66	492	2	)	)	PUNCT
bptjm-66	492	3	.	.	PUNCT
bptjm-66	493	1	21	21	NUM
bptjm-66	493	2	.	.	PUNCT
bptjm-66	494	1	west	west	PROPN
bptjm-66	494	2	chk	chk	PROPN
bptjm-66	494	3	,	,	PUNCT
bptjm-66	494	4	ritchie	ritchie	PROPN
bptjm-66	494	5	jc	jc	PROPN
bptjm-66	494	6	,	,	PUNCT
bptjm-66	494	7	boss	boss	PROPN
bptjm-66	494	8	-	-	PUNCT
bptjm-66	494	9	williams	williams	PROPN
bptjm-66	494	10	ka	ka	PROPN
bptjm-66	494	11	,	,	PUNCT
bptjm-66	494	12	weiss	weiss	PROPN
bptjm-66	494	13	jm	jm	PROPN
bptjm-66	494	14	.	.	PROPN
bptjm-66	494	15	antidepressant	antidepressant	ADJ
bptjm-66	494	16	drugs	drug	NOUN
bptjm-66	494	17	with	with	ADP
bptjm-66	494	18	differing	differ	VERB
bptjm-66	494	19	pharmacological	pharmacological	ADJ
bptjm-66	494	20	actions	action	NOUN
bptjm-66	494	21	decrease	decrease	VERB
bptjm-66	494	22	activity	activity	NOUN
bptjm-66	494	23	of	of	ADP
bptjm-66	494	24	locus	locus	ADJ
bptjm-66	494	25	coeruleus	coeruleus	NOUN
bptjm-66	494	26	neurons	neuron	NOUN
bptjm-66	494	27	.	.	PUNCT
bptjm-66	495	1	the	the	DET
bptjm-66	495	2	international	international	ADJ
bptjm-66	495	3	journal	journal	NOUN
bptjm-66	495	4	of	of	ADP
bptjm-66	495	5	neuropsychopharmacology	neuropsychopharmacology	PROPN
bptjm-66	495	6	.	.	PUNCT
bptjm-66	496	1	2008;12(05):627	2008;12(05):627	PROPN
bptjm-66	496	2	.	.	PUNCT
bptjm-66	497	1	22	22	NUM
bptjm-66	497	2	.	.	PUNCT
bptjm-66	498	1	sehgal	sehgal	PROPN
bptjm-66	498	2	n	n	CCONJ
bptjm-66	498	3	,	,	PUNCT
bptjm-66	498	4	smith	smith	PROPN
bptjm-66	498	5	hs	hs	PROPN
bptjm-66	498	6	,	,	PUNCT
bptjm-66	498	7	manchikanti	manchikanti	PROPN
bptjm-66	498	8	l.	l.	PROPN
bptjm-66	498	9	peripherally	peripherally	ADV
bptjm-66	498	10	acting	act	VERB
bptjm-66	498	11	opioids	opioid	NOUN
bptjm-66	498	12	and	and	CCONJ
bptjm-66	498	13	clinical	clinical	ADJ
bptjm-66	498	14	implications	implication	NOUN
bptjm-66	498	15	for	for	ADP
bptjm-66	498	16	pain	pain	NOUN
bptjm-66	498	17	control	control	NOUN
bptjm-66	498	18	.	.	PUNCT
bptjm-66	499	1	pain	pain	NOUN
bptjm-66	499	2	physician	physician	NOUN
bptjm-66	499	3	.	.	PUNCT
bptjm-66	500	1	2011;14(3):249	2011;14(3):249	NUM
bptjm-66	500	2	-	-	SYM
bptjm-66	500	3	258	258	NUM
bptjm-66	500	4	.	.	PUNCT
bptjm-66	501	1	23	23	NUM
bptjm-66	501	2	.	.	PUNCT
bptjm-66	502	1	murphy	murphy	PROPN
bptjm-66	502	2	pb	pb	PROPN
bptjm-66	502	3	,	,	PUNCT
bptjm-66	502	4	patel	patel	PROPN
bptjm-66	502	5	p	p	NOUN
bptjm-66	502	6	,	,	PUNCT
bptjm-66	502	7	barrett	barrett	PROPN
bptjm-66	502	8	mj	mj	PROPN
bptjm-66	502	9	.	.	PROPN
bptjm-66	502	10	morphine	morphine	PROPN
bptjm-66	502	11	.	.	PUNCT
bptjm-66	503	1	statpearls	statpearls	PROPN
bptjm-66	503	2	.	.	PUNCT
bptjm-66	504	1	treasure	treasure	NOUN
bptjm-66	504	2	island	island	NOUN
bptjm-66	504	3	(	(	PUNCT
bptjm-66	504	4	fl	fl	NOUN
bptjm-66	504	5	)	)	PUNCT
bptjm-66	504	6	24	24	NUM
bptjm-66	504	7	.	.	PUNCT
bptjm-66	504	8	pentazocine	pentazocine	NOUN
bptjm-66	504	9	.	.	PUNCT
bptjm-66	505	1	pubmed	pubmed	PROPN
bptjm-66	505	2	.	.	PROPN
bptjm-66	506	1	published	publish	VERB
bptjm-66	506	2	2012	2012	NUM
bptjm-66	506	3	.	.	PUNCT
bptjm-66	507	1	25	25	NUM
bptjm-66	507	2	.	.	X
bptjm-66	507	3	babaie	babaie	PROPN
bptjm-66	507	4	s	s	PROPN
bptjm-66	507	5	,	,	PUNCT
bptjm-66	507	6	arezou	arezou	NOUN
bptjm-66	507	7	taghvimi	taghvimi	NOUN
bptjm-66	507	8	,	,	PUNCT
bptjm-66	507	9	joo	joo	PROPN
bptjm-66	507	10	young	young	PROPN
bptjm-66	507	11	hong	hong	PROPN
bptjm-66	507	12	,	,	PUNCT
bptjm-66	507	13	hamed	hamed	PROPN
bptjm-66	507	14	hamishehkar	hamishehkar	PROPN
bptjm-66	507	15	,	,	PUNCT
bptjm-66	507	16	an	an	DET
bptjm-66	507	17	s	s	PROPN
bptjm-66	507	18	,	,	PUNCT
bptjm-66	507	19	kim	kim	PROPN
bptjm-66	507	20	kh	kh	PROPN
bptjm-66	507	21	.	.	PUNCT
bptjm-66	508	1	recent	recent	ADJ
bptjm-66	508	2	advances	advance	NOUN
bptjm-66	508	3	in	in	ADP
bptjm-66	508	4	pain	pain	NOUN
bptjm-66	508	5	management	management	NOUN
bptjm-66	508	6	based	base	VERB
bptjm-66	508	7	on	on	ADP
bptjm-66	508	8	nanoparticle	nanoparticle	NOUN
bptjm-66	508	9	technologies	technology	NOUN
bptjm-66	508	10	.	.	PUNCT
bptjm-66	509	1	2022;20(1	2022;20(1	NUM
bptjm-66	509	2	)	)	PUNCT
bptjm-66	509	3	.	.	PUNCT
bptjm-66	510	1	26	26	NUM
bptjm-66	510	2	.	.	PUNCT
bptjm-66	511	1	rehling	rehle	VERB
bptjm-66	511	2	t	t	PROPN
bptjm-66	511	3	,	,	PUNCT
bptjm-66	511	4	bjørkman	bjørkman	NOUN
bptjm-66	511	5	asd	asd	PROPN
bptjm-66	511	6	,	,	PUNCT
bptjm-66	511	7	andersen	andersen	PROPN
bptjm-66	511	8	mb	mb	PROPN
bptjm-66	511	9	,	,	PUNCT
bptjm-66	511	10	ekholm	ekholm	ADJ
bptjm-66	511	11	o	o	NOUN
bptjm-66	511	12	,	,	PUNCT
bptjm-66	511	13	molsted	molste	VERB
bptjm-66	511	14	s.	s.	PROPN
bptjm-66	511	15	diabetes	diabetes	PROPN
bptjm-66	511	16	is	be	AUX
bptjm-66	511	17	associated	associate	VERB
bptjm-66	511	18	with	with	ADP
bptjm-66	511	19	musculoskeletal	musculoskeletal	ADJ
bptjm-66	511	20	pain	pain	NOUN
bptjm-66	511	21	,	,	PUNCT
bptjm-66	511	22	osteoarthritis	osteoarthritis	NOUN
bptjm-66	511	23	,	,	PUNCT
bptjm-66	511	24	osteoporosis	osteoporosis	NOUN
bptjm-66	511	25	,	,	PUNCT
bptjm-66	511	26	and	and	CCONJ
bptjm-66	511	27	rheumatoid	rheumatoid	VERB
bptjm-66	511	28	arthritis	arthritis	NOUN
bptjm-66	511	29	.	.	PUNCT
bptjm-66	512	1	journal	journal	PROPN
bptjm-66	512	2	of	of	ADP
bptjm-66	512	3	diabetes	diabetes	NOUN
bptjm-66	512	4	research	research	NOUN
bptjm-66	512	5	.	.	PUNCT
bptjm-66	513	1	2019;2019:1	2019;2019:1	NUM
bptjm-66	513	2	-	-	SYM
bptjm-66	513	3	6	6	NUM
bptjm-66	513	4	.	.	NOUN
bptjm-66	513	5	27	27	NUM
bptjm-66	513	6	.	.	PUNCT
bptjm-66	514	1	kesmati	kesmati	PROPN
bptjm-66	514	2	m	m	PROPN
bptjm-66	514	3	,	,	PUNCT
bptjm-66	514	4	torabi	torabi	NOUN
bptjm-66	514	5	m.	m.	NOUN
bptjm-66	514	6	interaction	interaction	NOUN
bptjm-66	514	7	between	between	ADP
bptjm-66	514	8	analgesic	analgesic	ADJ
bptjm-66	514	9	effect	effect	NOUN
bptjm-66	514	10	of	of	ADP
bptjm-66	514	11	nano	nano	NOUN
bptjm-66	514	12	and	and	CCONJ
bptjm-66	514	13	conventional	conventional	ADJ
bptjm-66	514	14	size	size	NOUN
bptjm-66	514	15	of	of	ADP
bptjm-66	514	16	zinc	zinc	NOUN
bptjm-66	514	17	oxide	oxide	NOUN
bptjm-66	514	18	and	and	CCONJ
bptjm-66	514	19	opioidergic	opioidergic	ADJ
bptjm-66	514	20	system	system	NOUN
bptjm-66	514	21	activity	activity	NOUN
bptjm-66	514	22	in	in	ADP
bptjm-66	514	23	animal	animal	NOUN
bptjm-66	514	24	model	model	NOUN
bptjm-66	514	25	of	of	ADP
bptjm-66	514	26	acute	acute	ADJ
bptjm-66	514	27	pain	pain	NOUN
bptjm-66	514	28	.	.	PUNCT
bptjm-66	515	1	basic	basic	ADJ
bptjm-66	515	2	and	and	CCONJ
bptjm-66	515	3	clinical	clinical	ADJ
bptjm-66	515	4	neuroscience	neuroscience	NOUN
bptjm-66	515	5	.	.	PUNCT
bptjm-66	516	1	2014;5(1):80	2014;5(1):80	NUM
bptjm-66	516	2	-	-	SYM
bptjm-66	516	3	87	87	NUM
bptjm-66	516	4	.	.	PUNCT
bptjm-66	517	1	28	28	NUM
bptjm-66	517	2	.	.	PUNCT
bptjm-66	518	1	wu	wu	PROPN
bptjm-66	518	2	pc	pc	PROPN
bptjm-66	518	3	,	,	PUNCT
bptjm-66	518	4	hsiao	hsiao	PROPN
bptjm-66	518	5	ht	ht	PROPN
bptjm-66	518	6	,	,	PUNCT
bptjm-66	518	7	lin	lin	PROPN
bptjm-66	518	8	yc	yc	PROPN
bptjm-66	518	9	,	,	PUNCT
bptjm-66	518	10	shieh	shieh	PROPN
bptjm-66	518	11	db	db	PROPN
bptjm-66	518	12	,	,	PUNCT
bptjm-66	518	13	liu	liu	PROPN
bptjm-66	518	14	yc	yc	PROPN
bptjm-66	518	15	.	.	PUNCT
bptjm-66	519	1	the	the	DET
bptjm-66	519	2	analgesia	analgesia	PROPN
bptjm-66	519	3	efficiency	efficiency	NOUN
bptjm-66	519	4	of	of	ADP
bptjm-66	519	5	ultrasmall	ultrasmall	PROPN
bptjm-66	519	6	magnetic	magnetic	ADJ
bptjm-66	519	7	iron	iron	NOUN
bptjm-66	519	8	oxide	oxide	NOUN
bptjm-66	519	9	nanoparticles	nanoparticle	NOUN
bptjm-66	519	10	in	in	ADP
bptjm-66	519	11	mice	mouse	NOUN
bptjm-66	519	12	chronic	chronic	ADJ
bptjm-66	519	13	inflammatory	inflammatory	ADJ
bptjm-66	519	14	pain	pain	NOUN
bptjm-66	519	15	model	model	NOUN
bptjm-66	519	16	.	.	PUNCT
bptjm-66	520	1	nanomedicine	nanomedicine	NOUN
bptjm-66	520	2	:	:	PUNCT
bptjm-66	520	3	nanotechnology	nanotechnology	NOUN
bptjm-66	520	4	,	,	PUNCT
bptjm-66	520	5	biology	biology	NOUN
bptjm-66	520	6	and	and	CCONJ
bptjm-66	520	7	medicine	medicine	NOUN
bptjm-66	520	8	.	.	PUNCT
bptjm-66	521	1	2017;13(6):1975	2017;13(6):1975	NUM
bptjm-66	521	2	-	-	PUNCT
bptjm-66	521	3	1981	1981	NUM
bptjm-66	521	4	.	.	PUNCT
bptjm-66	522	1	29	29	NUM
bptjm-66	522	2	.	.	PUNCT
bptjm-66	523	1	bala	bala	PROPN
bptjm-66	523	2	vm	vm	PROPN
bptjm-66	523	3	,	,	PUNCT
bptjm-66	523	4	dimitra	dimitra	PROPN
bptjm-66	523	5	ioanna	ioanna	PROPN
bptjm-66	523	6	lampropoulou	lampropoulou	PROPN
bptjm-66	523	7	,	,	PUNCT
bptjm-66	523	8	stamatiki	stamatiki	PROPN
bptjm-66	523	9	grammatikaki	grammatikaki	NOUN
bptjm-66	523	10	,	,	PUNCT
bptjm-66	523	11	et	et	PROPN
bptjm-66	523	12	al	al	PROPN
bptjm-66	523	13	.	.	PROPN
bptjm-66	523	14	nanoparticle	nanoparticle	NOUN
bptjm-66	523	15	-	-	PUNCT
bptjm-66	523	16	mediated	mediate	VERB
bptjm-66	523	17	hyperthermia	hyperthermia	NOUN
bptjm-66	523	18	and	and	CCONJ
bptjm-66	523	19	cytotoxicity	cytotoxicity	NOUN
bptjm-66	523	20	mechanisms	mechanism	NOUN
bptjm-66	523	21	in	in	ADP
bptjm-66	523	22	cancer	cancer	NOUN
bptjm-66	523	23	.	.	PUNCT
bptjm-66	524	1	international	international	ADJ
bptjm-66	524	2	journal	journal	NOUN
bptjm-66	524	3	of	of	ADP
bptjm-66	524	4	molecular	molecular	ADJ
bptjm-66	524	5	sciences	science	NOUN
bptjm-66	524	6	.	.	PUNCT
bptjm-66	525	1	2023;25(1):296	2023;25(1):296	NUM
bptjm-66	525	2	-	-	PUNCT
bptjm-66	525	3	296	296	NUM
bptjm-66	525	4	.	.	PUNCT
bptjm-66	526	1	30	30	NUM
bptjm-66	526	2	.	.	PUNCT
bptjm-66	527	1	sztandera	sztandera	PROPN
bptjm-66	527	2	k	k	PROPN
bptjm-66	527	3	,	,	PUNCT
bptjm-66	527	4	gorzkiewicz	gorzkiewicz	PROPN
bptjm-66	527	5	m	m	PROPN
bptjm-66	527	6	,	,	PUNCT
bptjm-66	527	7	klajnert	klajnert	NOUN
bptjm-66	527	8	-	-	PUNCT
bptjm-66	527	9	maculewicz	maculewicz	PROPN
bptjm-66	527	10	b.	b.	NOUN
bptjm-66	527	11	gold	gold	NOUN
bptjm-66	527	12	nanoparticles	nanoparticle	NOUN
bptjm-66	527	13	in	in	ADP
bptjm-66	527	14	cancer	cancer	NOUN
bptjm-66	527	15	treatment	treatment	NOUN
bptjm-66	527	16	.	.	PUNCT
bptjm-66	528	1	molecular	molecular	ADJ
bptjm-66	528	2	pharmaceutics	pharmaceutic	NOUN
bptjm-66	528	3	.	.	PUNCT
bptjm-66	529	1	2018;16(1):1	2018;16(1):1	NUM
bptjm-66	529	2	-	-	SYM
bptjm-66	529	3	23	23	NUM
bptjm-66	529	4	.	.	PUNCT
bptjm-66	530	1	31	31	NUM
bptjm-66	530	2	.	.	PUNCT
bptjm-66	531	1	el	el	PROPN
bptjm-66	531	2	-	-	PUNCT
bptjm-66	531	3	sayed	say	VERB
bptjm-66	531	4	ih	ih	PROPN
bptjm-66	531	5	,	,	PUNCT
bptjm-66	531	6	huang	huang	PROPN
bptjm-66	531	7	x	x	PROPN
bptjm-66	531	8	,	,	PUNCT
bptjm-66	531	9	el	el	PROPN
bptjm-66	531	10	-	-	PUNCT
bptjm-66	531	11	sayed	say	VERB
bptjm-66	531	12	ma	ma	PROPN
bptjm-66	531	13	.	.	PROPN
bptjm-66	531	14	surface	surface	PROPN
bptjm-66	531	15	plasmon	plasmon	NOUN
bptjm-66	531	16	resonance	resonance	NOUN
bptjm-66	531	17	scattering	scattering	NOUN
bptjm-66	531	18	and	and	CCONJ
bptjm-66	531	19	absorption	absorption	NOUN
bptjm-66	531	20	of	of	ADP
bptjm-66	531	21	anti	anti	ADJ
bptjm-66	531	22	-	-	ADJ
bptjm-66	531	23	egfr	egfr	ADJ
bptjm-66	531	24	antibody	antibody	NOUN
bptjm-66	531	25	conjugated	conjugate	VERB
bptjm-66	531	26	gold	gold	ADJ
bptjm-66	531	27	nanoparticles	nanoparticle	NOUN
bptjm-66	531	28	in	in	ADP
bptjm-66	531	29	cancer	cancer	NOUN
bptjm-66	531	30	diagnostics	diagnostic	NOUN
bptjm-66	531	31	:	:	PUNCT
bptjm-66	531	32	applications	application	NOUN
bptjm-66	531	33	in	in	ADP
bptjm-66	531	34	oral	oral	ADJ
bptjm-66	531	35	cancer	cancer	NOUN
bptjm-66	531	36	.	.	PUNCT
bptjm-66	532	1	nano	nano	NOUN
bptjm-66	532	2	letters	letter	NOUN
bptjm-66	532	3	.	.	PUNCT
bptjm-66	533	1	2005;5(5):829	2005;5(5):829	X
bptjm-66	533	2	-	-	SYM
bptjm-66	533	3	834	834	NUM
bptjm-66	533	4	.	.	PUNCT
bptjm-66	534	1	32	32	NUM
bptjm-66	534	2	.	.	PUNCT
bptjm-66	535	1	gold	gold	NOUN
bptjm-66	535	2	nanoparticles	nanoparticle	NOUN
bptjm-66	535	3	reverse	reverse	VERB
bptjm-66	535	4	brain	brain	NOUN
bptjm-66	535	5	deficits	deficit	NOUN
bptjm-66	535	6	in	in	ADP
bptjm-66	535	7	multiple	multiple	ADJ
bptjm-66	535	8	sclerosis	sclerosis	NOUN
bptjm-66	535	9	,	,	PUNCT
bptjm-66	535	10	parkinson	parkinson	NOUN
bptjm-66	535	11	’s	’s	PART
bptjm-66	535	12	.	.	PUNCT
bptjm-66	536	1	www.utsouthwestern.edu	www.utsouthwestern.edu	PROPN
bptjm-66	536	2	.	.	PUNCT
bptjm-66	537	1	published	publish	VERB
bptjm-66	537	2	february	february	PROPN
bptjm-66	537	3	13	13	NUM
bptjm-66	537	4	,	,	PUNCT
bptjm-66	537	5	2024	2024	NUM
bptjm-66	537	6	.	.	PUNCT
bptjm-66	538	1	33	33	NUM
bptjm-66	538	2	.	.	PUNCT
bptjm-66	539	1	xu	xu	PROPN
bptjm-66	539	2	y	y	PROPN
bptjm-66	539	3	,	,	PUNCT
bptjm-66	539	4	dong	dong	PROPN
bptjm-66	539	5	x	x	PROPN
bptjm-66	539	6	,	,	PUNCT
bptjm-66	539	7	xu	xu	PROPN
bptjm-66	540	1	h	h	PROPN
bptjm-66	540	2	,	,	PUNCT
bptjm-66	540	3	jiao	jiao	PROPN
bptjm-66	540	4	p	p	PROPN
bptjm-66	540	5	,	,	PUNCT
bptjm-66	540	6	zhao	zhao	PROPN
bptjm-66	540	7	lx	lx	NOUN
bptjm-66	540	8	,	,	PUNCT
bptjm-66	540	9	su	su	PROPN
bptjm-66	540	10	g.	g.	PROPN
bptjm-66	540	11	nanomaterial	nanomaterial	PROPN
bptjm-66	540	12	-	-	PUNCT
bptjm-66	540	13	based	base	VERB
bptjm-66	540	14	drug	drug	NOUN
bptjm-66	540	15	delivery	delivery	NOUN
bptjm-66	540	16	systems	systems	PROPN
bptjm-66	540	17	berkeley	berkeley	PROPN
bptjm-66	540	18	pharma	pharma	PROPN
bptjm-66	540	19	tech	tech	NOUN
bptjm-66	540	20	journal	journal	NOUN
bptjm-66	540	21	of	of	ADP
bptjm-66	540	22	medicine	medicine	NOUN
bptjm-66	540	23	|	|	ADV
bptjm-66	540	24	32	32	NUM
bptjm-66	540	25	for	for	ADP
bptjm-66	540	26	pain	pain	NOUN
bptjm-66	540	27	treatment	treatment	NOUN
bptjm-66	540	28	and	and	CCONJ
bptjm-66	540	29	relief	relief	NOUN
bptjm-66	540	30	:	:	PUNCT
bptjm-66	540	31	from	from	ADP
bptjm-66	540	32	the	the	DET
bptjm-66	540	33	delivery	delivery	NOUN
bptjm-66	540	34	of	of	ADP
bptjm-66	540	35	a	a	DET
bptjm-66	540	36	single	single	ADJ
bptjm-66	540	37	drug	drug	NOUN
bptjm-66	540	38	to	to	ADP
bptjm-66	540	39	co	co	NOUN
bptjm-66	540	40	-	-	NOUN
bptjm-66	540	41	delivery	delivery	NOUN
bptjm-66	540	42	of	of	ADP
bptjm-66	540	43	multiple	multiple	ADJ
bptjm-66	540	44	therapeutics	therapeutic	NOUN
bptjm-66	540	45	.	.	PUNCT
bptjm-66	541	1	pharmaceutics	pharmaceutic	NOUN
bptjm-66	541	2	.	.	PUNCT
bptjm-66	542	1	2023;15(9):2309	2023;15(9):2309	PROPN
bptjm-66	542	2	-	-	PUNCT
bptjm-66	542	3	2309	2309	NUM
bptjm-66	542	4	.	.	PUNCT
bptjm-66	543	1	34	34	NUM
bptjm-66	543	2	.	.	PUNCT
bptjm-66	544	1	feng	feng	PROPN
bptjm-66	544	2	z	z	PROPN
bptjm-66	544	3	,	,	PUNCT
bptjm-66	544	4	gu	gu	PROPN
bptjm-66	544	5	y	y	PROPN
bptjm-66	544	6	,	,	PUNCT
bptjm-66	544	7	yuan	yuan	PROPN
bptjm-66	544	8	m	m	PROPN
bptjm-66	544	9	,	,	PUNCT
bptjm-66	544	10	xiao	xiao	PROPN
bptjm-66	544	11	r	r	PROPN
bptjm-66	544	12	,	,	PUNCT
bptjm-66	544	13	fei	fei	PROPN
bptjm-66	544	14	z.	z.	PROPN
bptjm-66	544	15	clinical	clinical	PROPN
bptjm-66	544	16	trials	trial	NOUN
bptjm-66	544	17	of	of	ADP
bptjm-66	544	18	liposomes	liposome	NOUN
bptjm-66	544	19	in	in	ADP
bptjm-66	544	20	children	child	NOUN
bptjm-66	544	21	’s	’s	PART
bptjm-66	544	22	anticancer	anticancer	NOUN
bptjm-66	544	23	therapy	therapy	NOUN
bptjm-66	544	24	:	:	PUNCT
bptjm-66	544	25	a	a	DET
bptjm-66	544	26	comprehensive	comprehensive	ADJ
bptjm-66	544	27	analysis	analysis	NOUN
bptjm-66	544	28	of	of	ADP
bptjm-66	544	29	trials	trial	NOUN
bptjm-66	544	30	registered	register	VERB
bptjm-66	544	31	on	on	ADP
bptjm-66	544	32	clinicaltrials.gov	clinicaltrials.gov	PROPN
bptjm-66	544	33	.	.	PUNCT
bptjm-66	544	34	international	international	ADJ
bptjm-66	544	35	journal	journal	PROPN
bptjm-66	544	36	of	of	ADP
bptjm-66	544	37	nanomedicine	nanomedicine	NOUN
bptjm-66	544	38	.	.	PUNCT
bptjm-66	545	1	2022;volume	2022;volume	NUM
bptjm-66	545	2	17:1843	17:1843	NUM
bptjm-66	545	3	-	-	SYM
bptjm-66	545	4	1850	1850	NUM
bptjm-66	545	5	.	.	PUNCT
bptjm-66	546	1	35	35	NUM
bptjm-66	546	2	.	.	PUNCT
bptjm-66	546	3	lipid	lipid	NOUN
bptjm-66	546	4	-	-	PUNCT
bptjm-66	546	5	based	base	VERB
bptjm-66	546	6	nanoparticles	nanoparticle	NOUN
bptjm-66	546	7	for	for	ADP
bptjm-66	546	8	dermal	dermal	ADJ
bptjm-66	546	9	drug	drug	NOUN
bptjm-66	546	10	delivery	delivery	NOUN
bptjm-66	546	11	.	.	PUNCT
bptjm-66	547	1	organic	organic	ADJ
bptjm-66	547	2	materials	material	NOUN
bptjm-66	547	3	as	as	ADP
bptjm-66	547	4	smart	smart	ADJ
bptjm-66	547	5	nanocarriers	nanocarrier	NOUN
bptjm-66	547	6	for	for	ADP
bptjm-66	547	7	drug	drug	NOUN
bptjm-66	547	8	delivery	delivery	NOUN
bptjm-66	547	9	.	.	PUNCT
bptjm-66	548	1	published	publish	VERB
bptjm-66	548	2	online	online	ADJ
bptjm-66	548	3	january	january	PROPN
bptjm-66	548	4	1	1	NUM
bptjm-66	548	5	,	,	PUNCT
bptjm-66	548	6	2018:369	2018:369	NUM
bptjm-66	548	7	-	-	SYM
bptjm-66	548	8	413	413	NUM
bptjm-66	548	9	.	.	PUNCT
bptjm-66	549	1	36	36	NUM
bptjm-66	549	2	.	.	PUNCT
bptjm-66	550	1	yadav	yadav	PROPN
bptjm-66	550	2	hn	hn	PROPN
bptjm-66	550	3	,	,	PUNCT
bptjm-66	550	4	vishwakarma	vishwakarma	VERB
bptjm-66	550	5	vk	vk	PROPN
bptjm-66	550	6	,	,	PUNCT
bptjm-66	550	7	paswan	paswan	X
bptjm-66	550	8	sk	sk	PROPN
bptjm-66	550	9	,	,	PUNCT
bptjm-66	550	10	arora	arora	PROPN
bptjm-66	550	11	t	t	PROPN
bptjm-66	550	12	,	,	PUNCT
bptjm-66	550	13	verma	verma	PROPN
bptjm-66	550	14	rk	rk	PROPN
bptjm-66	550	15	.	.	PUNCT
bptjm-66	550	16	pain	pain	NOUN
bptjm-66	550	17	allaying	allay	VERB
bptjm-66	550	18	epalrestat	epalrestat	NOUN
bptjm-66	550	19	-	-	PUNCT
bptjm-66	550	20	loaded	load	VERB
bptjm-66	550	21	lipid	lipid	NOUN
bptjm-66	550	22	nanoformulation	nanoformulation	NOUN
bptjm-66	550	23	for	for	ADP
bptjm-66	550	24	the	the	DET
bptjm-66	550	25	diabetic	diabetic	ADJ
bptjm-66	550	26	neuropathic	neuropathic	ADJ
bptjm-66	550	27	pain	pain	NOUN
bptjm-66	550	28	interventions	intervention	NOUN
bptjm-66	550	29	:	:	PUNCT
bptjm-66	550	30	design	design	NOUN
bptjm-66	550	31	,	,	PUNCT
bptjm-66	550	32	development	development	NOUN
bptjm-66	550	33	,	,	PUNCT
bptjm-66	550	34	and	and	CCONJ
bptjm-66	550	35	animal	animal	NOUN
bptjm-66	550	36	study	study	NOUN
bptjm-66	550	37	.	.	PUNCT
bptjm-66	551	1	current	current	ADJ
bptjm-66	551	2	drug	drug	NOUN
bptjm-66	551	3	metabolism	metabolism	NOUN
bptjm-66	551	4	.	.	PUNCT
bptjm-66	552	1	2022;23(7):571	2022;23(7):571	NUM
bptjm-66	552	2	-	-	PUNCT
bptjm-66	552	3	583	583	NUM
bptjm-66	552	4	.	.	PUNCT
bptjm-66	553	1	37	37	NUM
bptjm-66	553	2	.	.	PUNCT
bptjm-66	554	1	khan	khan	PROPN
bptjm-66	554	2	s	s	PROPN
bptjm-66	554	3	,	,	PUNCT
bptjm-66	554	4	sharma	sharma	PROPN
bptjm-66	554	5	a	a	PROPN
bptjm-66	554	6	,	,	PUNCT
bptjm-66	554	7	jain	jain	NOUN
bptjm-66	554	8	v.	v.	ADP
bptjm-66	554	9	an	an	DET
bptjm-66	554	10	overview	overview	NOUN
bptjm-66	554	11	of	of	ADP
bptjm-66	554	12	nanostructured	nanostructure	VERB
bptjm-66	554	13	lipid	lipid	NOUN
bptjm-66	554	14	carriers	carrier	NOUN
bptjm-66	554	15	and	and	CCONJ
bptjm-66	554	16	its	its	PRON
bptjm-66	554	17	application	application	NOUN
bptjm-66	554	18	in	in	ADP
bptjm-66	554	19	drug	drug	NOUN
bptjm-66	554	20	delivery	delivery	NOUN
bptjm-66	554	21	through	through	ADP
bptjm-66	554	22	different	different	ADJ
bptjm-66	554	23	routes	route	NOUN
bptjm-66	554	24	.	.	PUNCT
bptjm-66	555	1	advanced	advanced	ADJ
bptjm-66	555	2	pharmaceutical	pharmaceutical	ADJ
bptjm-66	555	3	bulletin	bulletin	NOUN
bptjm-66	555	4	.	.	PUNCT
bptjm-66	556	1	38	38	NUM
bptjm-66	556	2	.	.	PUNCT
bptjm-66	557	1	zhang	zhang	PROPN
bptjm-66	557	2	y	y	PROPN
bptjm-66	557	3	,	,	PUNCT
bptjm-66	557	4	yue	yue	PROPN
bptjm-66	557	5	y	y	PROPN
bptjm-66	557	6	,	,	PUNCT
bptjm-66	557	7	chang	chang	PROPN
bptjm-66	557	8	m.	m.	PROPN
bptjm-66	557	9	local	local	ADJ
bptjm-66	557	10	anaesthetic	anaesthetic	ADJ
bptjm-66	557	11	pain	pain	NOUN
bptjm-66	557	12	relief	relief	NOUN
bptjm-66	557	13	therapy	therapy	NOUN
bptjm-66	557	14	:	:	PUNCT
bptjm-66	557	15	in	in	ADP
bptjm-66	557	16	vitro	vitro	X
bptjm-66	557	17	and	and	CCONJ
bptjm-66	557	18	in	in	ADP
bptjm-66	557	19	vivo	vivo	ADJ
bptjm-66	557	20	evaluation	evaluation	NOUN
bptjm-66	557	21	of	of	ADP
bptjm-66	557	22	a	a	DET
bptjm-66	557	23	nanotechnological	nanotechnological	ADJ
bptjm-66	557	24	formulation	formulation	NOUN
bptjm-66	557	25	co	co	VERB
bptjm-66	557	26	-	-	VERB
bptjm-66	557	27	loaded	load	VERB
bptjm-66	557	28	with	with	ADP
bptjm-66	557	29	ropivacaine	ropivacaine	NOUN
bptjm-66	557	30	and	and	CCONJ
bptjm-66	557	31	dexamethasone	dexamethasone	NOUN
bptjm-66	557	32	.	.	PUNCT
bptjm-66	557	33	biomedicine	biomedicine	PROPN
bptjm-66	557	34	&	&	CCONJ
bptjm-66	557	35	pharmacotherapy	pharmacotherapy	NOUN
bptjm-66	557	36	.	.	PUNCT
bptjm-66	558	1	2017;96:443	2017;96:443	NUM
bptjm-66	558	2	-	-	PUNCT
bptjm-66	558	3	449	449	NUM
bptjm-66	558	4	.	.	NOUN
bptjm-66	558	5	39	39	NUM
bptjm-66	558	6	.	.	PUNCT
bptjm-66	559	1	li	li	PROPN
bptjm-66	559	2	x	x	PROPN
bptjm-66	559	3	,	,	PUNCT
bptjm-66	559	4	xu	xu	PROPN
bptjm-66	559	5	x	x	PROPN
bptjm-66	559	6	,	,	PUNCT
bptjm-66	559	7	xu	xu	PROPN
bptjm-66	559	8	m	m	PROPN
bptjm-66	559	9	,	,	PUNCT
bptjm-66	559	10	geng	geng	PROPN
bptjm-66	559	11	z	z	PROPN
bptjm-66	559	12	,	,	PUNCT
bptjm-66	559	13	ji	ji	PROPN
bptjm-66	559	14	p	p	PROPN
bptjm-66	559	15	,	,	PUNCT
bptjm-66	559	16	liu	liu	PROPN
bptjm-66	559	17	y.	y.	PROPN
bptjm-66	559	18	hydrogel	hydrogel	PROPN
bptjm-66	559	19	systems	system	NOUN
bptjm-66	559	20	for	for	ADP
bptjm-66	559	21	targeted	target	VERB
bptjm-66	559	22	cancer	cancer	NOUN
bptjm-66	559	23	therapy	therapy	NOUN
bptjm-66	559	24	.	.	PUNCT
bptjm-66	560	1	frontiers	frontier	NOUN
bptjm-66	560	2	in	in	ADP
bptjm-66	560	3	bioengineering	bioengineering	NOUN
bptjm-66	560	4	and	and	CCONJ
bptjm-66	560	5	biotechnology	biotechnology	NOUN
bptjm-66	560	6	.	.	PUNCT
bptjm-66	561	1	2023;11	2023;11	X
bptjm-66	561	2	.	.	PUNCT
bptjm-66	562	1	40	40	NUM
bptjm-66	562	2	.	.	PUNCT
bptjm-66	563	1	bacchetta	bacchetta	NOUN
bptjm-66	563	2	r	r	NOUN
bptjm-66	563	3	,	,	PUNCT
bptjm-66	563	4	gambineri	gambineri	NOUN
bptjm-66	563	5	e	e	PROPN
bptjm-66	563	6	,	,	PUNCT
bptjm-66	563	7	roncarolo	roncarolo	VERB
bptjm-66	563	8	mg	mg	PROPN
bptjm-66	563	9	.	.	PUNCT
bptjm-66	564	1	role	role	NOUN
bptjm-66	564	2	of	of	ADP
bptjm-66	564	3	regulatory	regulatory	ADJ
bptjm-66	564	4	t	t	NOUN
bptjm-66	564	5	cells	cell	NOUN
bptjm-66	564	6	and	and	CCONJ
bptjm-66	564	7	foxp3	foxp3	NOUN
bptjm-66	564	8	in	in	ADP
bptjm-66	564	9	human	human	ADJ
bptjm-66	564	10	diseases	disease	NOUN
bptjm-66	564	11	.	.	PUNCT
bptjm-66	565	1	j	j	PROPN
bptjm-66	565	2	allergy	allergy	PROPN
bptjm-66	565	3	clin	clin	PROPN
bptjm-66	565	4	immunol	immunol	PROPN
bptjm-66	565	5	.	.	PUNCT
bptjm-66	566	1	2007	2007	NUM
bptjm-66	566	2	aug	aug	NOUN
bptjm-66	566	3	;	;	PUNCT
bptjm-66	566	4	120(2):227	120(2):227	X
bptjm-66	566	5	-	-	SYM
bptjm-66	566	6	35	35	NUM
bptjm-66	566	7	;	;	PUNCT
bptjm-66	566	8	41	41	NUM
bptjm-66	566	9	.	.	PUNCT
bptjm-66	567	1	wu	wu	PROPN
bptjm-66	567	2	pc	pc	PROPN
bptjm-66	567	3	,	,	PUNCT
bptjm-66	567	4	hsiao	hsiao	PROPN
bptjm-66	567	5	ht	ht	PROPN
bptjm-66	567	6	,	,	PUNCT
bptjm-66	567	7	lin	lin	PROPN
bptjm-66	567	8	yc	yc	PROPN
bptjm-66	567	9	,	,	PUNCT
bptjm-66	567	10	shieh	shieh	PROPN
bptjm-66	567	11	db	db	PROPN
bptjm-66	567	12	,	,	PUNCT
bptjm-66	567	13	liu	liu	PROPN
bptjm-66	567	14	yc	yc	PROPN
bptjm-66	567	15	.	.	PUNCT
bptjm-66	568	1	the	the	DET
bptjm-66	568	2	analgesia	analgesia	PROPN
bptjm-66	568	3	efficiency	efficiency	NOUN
bptjm-66	568	4	of	of	ADP
bptjm-66	568	5	ultrasmall	ultrasmall	PROPN
bptjm-66	568	6	magnetic	magnetic	ADJ
bptjm-66	568	7	iron	iron	NOUN
bptjm-66	568	8	oxide	oxide	NOUN
bptjm-66	568	9	nanoparticles	nanoparticle	NOUN
bptjm-66	568	10	in	in	ADP
bptjm-66	568	11	mice	mouse	NOUN
bptjm-66	568	12	chronic	chronic	ADJ
bptjm-66	568	13	inflammatory	inflammatory	ADJ
bptjm-66	568	14	pain	pain	NOUN
bptjm-66	568	15	model	model	NOUN
bptjm-66	568	16	.	.	PUNCT
bptjm-66	569	1	nanomedicine	nanomedicine	NOUN
bptjm-66	569	2	:	:	PUNCT
bptjm-66	569	3	nanotechnology	nanotechnology	NOUN
bptjm-66	569	4	,	,	PUNCT
bptjm-66	569	5	biology	biology	NOUN
bptjm-66	569	6	and	and	CCONJ
bptjm-66	569	7	medicine	medicine	NOUN
bptjm-66	569	8	.	.	PUNCT
bptjm-66	570	1	2017;13(6):1975	2017;13(6):1975	NUM
bptjm-66	570	2	-	-	PUNCT
bptjm-66	570	3	1981	1981	NUM
bptjm-66	570	4	.	.	PUNCT
bptjm-66	571	1	42	42	NUM
bptjm-66	571	2	.	.	PUNCT
bptjm-66	572	1	liu	liu	PROPN
bptjm-66	572	2	y	y	PROPN
bptjm-66	572	3	,	,	PUNCT
bptjm-66	572	4	geng	geng	PROPN
bptjm-66	572	5	y	y	PROPN
bptjm-66	572	6	,	,	PUNCT
bptjm-66	572	7	yue	yue	PROPN
bptjm-66	572	8	b	b	PROPN
bptjm-66	572	9	,	,	PUNCT
bptjm-66	572	10	lo	lo	PROPN
bptjm-66	572	11	pc	pc	PROPN
bptjm-66	572	12	,	,	PUNCT
bptjm-66	572	13	huang	huang	PROPN
bptjm-66	572	14	j	j	PROPN
bptjm-66	572	15	,	,	PUNCT
bptjm-66	572	16	jin	jin	PROPN
bptjm-66	572	17	h.	h.	PROPN
bptjm-66	572	18	injectable	injectable	ADJ
bptjm-66	572	19	hydrogel	hydrogel	NOUN
bptjm-66	572	20	as	as	ADP
bptjm-66	572	21	a	a	DET
bptjm-66	572	22	unique	unique	ADJ
bptjm-66	572	23	platform	platform	NOUN
bptjm-66	572	24	for	for	ADP
bptjm-66	572	25	antitumor	antitumor	PROPN
bptjm-66	572	26	therapy	therapy	NOUN
bptjm-66	572	27	targeting	target	VERB
bptjm-66	572	28	immunosuppressive	immunosuppressive	ADJ
bptjm-66	572	29	tumor	tumor	NOUN
bptjm-66	572	30	microenvironment	microenvironment	NOUN
bptjm-66	572	31	.	.	PUNCT
bptjm-66	573	1	frontiers	frontier	NOUN
bptjm-66	573	2	in	in	ADP
bptjm-66	573	3	immunology	immunology	NOUN
bptjm-66	573	4	.	.	PUNCT
bptjm-66	574	1	2022;12	2022;12	X
bptjm-66	574	2	.	.	PUNCT
bptjm-66	575	1	43	43	NUM
bptjm-66	575	2	.	.	PUNCT
bptjm-66	576	1	lu	lu	PROPN
bptjm-66	576	2	y	y	PROPN
bptjm-66	576	3	,	,	PUNCT
bptjm-66	576	4	zhang	zhang	PROPN
bptjm-66	576	5	e	e	PROPN
bptjm-66	576	6	,	,	PUNCT
bptjm-66	576	7	yang	yang	PROPN
bptjm-66	576	8	j	j	PROPN
bptjm-66	576	9	,	,	PUNCT
bptjm-66	576	10	cao	cao	PROPN
bptjm-66	576	11	z.	z.	PROPN
bptjm-66	576	12	strategies	strategy	NOUN
bptjm-66	576	13	to	to	PART
bptjm-66	576	14	improve	improve	VERB
bptjm-66	576	15	micelle	micelle	NOUN
bptjm-66	576	16	stability	stability	NOUN
bptjm-66	576	17	for	for	ADP
bptjm-66	576	18	drug	drug	NOUN
bptjm-66	576	19	delivery	delivery	NOUN
bptjm-66	576	20	.	.	PUNCT
bptjm-66	577	1	nano	nano	NOUN
bptjm-66	577	2	research	research	NOUN
bptjm-66	577	3	.	.	PUNCT
bptjm-66	578	1	2018;11(10):4985	2018;11(10):4985	X
bptjm-66	578	2	-	-	X
bptjm-66	578	3	4998	4998	NUM
bptjm-66	578	4	.	.	PUNCT
bptjm-66	579	1	44	44	NUM
bptjm-66	579	2	.	.	PUNCT
bptjm-66	580	1	zheng	zheng	PROPN
bptjm-66	580	2	x	x	PROPN
bptjm-66	580	3	,	,	PUNCT
bptjm-66	580	4	xie	xie	PROPN
bptjm-66	580	5	j	j	PROPN
bptjm-66	580	6	,	,	PUNCT
bptjm-66	580	7	zhang	zhang	PROPN
bptjm-66	580	8	x	x	PROPN
bptjm-66	580	9	,	,	PUNCT
bptjm-66	580	10	et	et	PROPN
bptjm-66	580	11	al	al	PROPN
bptjm-66	580	12	.	.	PUNCT
bptjm-66	581	1	an	an	DET
bptjm-66	581	2	overview	overview	NOUN
bptjm-66	581	3	of	of	ADP
bptjm-66	581	4	polymeric	polymeric	ADJ
bptjm-66	581	5	nanomicelles	nanomicelle	NOUN
bptjm-66	581	6	in	in	ADP
bptjm-66	581	7	clinical	clinical	ADJ
bptjm-66	581	8	trials	trial	NOUN
bptjm-66	581	9	and	and	CCONJ
bptjm-66	581	10	on	on	ADP
bptjm-66	581	11	the	the	DET
bptjm-66	581	12	market	market	NOUN
bptjm-66	581	13	.	.	PUNCT
bptjm-66	582	1	chinese	chinese	ADJ
bptjm-66	582	2	chemical	chemical	PROPN
bptjm-66	582	3	letters	letter	NOUN
bptjm-66	582	4	.	.	PUNCT
bptjm-66	583	1	2021;32(1):243	2021;32(1):243	NUM
bptjm-66	583	2	-	-	PUNCT
bptjm-66	583	3	257	257	NUM
bptjm-66	583	4	.	.	PUNCT
bptjm-66	584	1	45	45	NUM
bptjm-66	584	2	.	.	PUNCT
bptjm-66	585	1	saif	saif	PROPN
bptjm-66	585	2	mw	mw	PROPN
bptjm-66	585	3	,	,	PUNCT
bptjm-66	585	4	podoltsev	podoltsev	NOUN
bptjm-66	585	5	na	na	PROPN
bptjm-66	585	6	,	,	PUNCT
bptjm-66	585	7	rubin	rubin	PROPN
bptjm-66	585	8	ms	ms	PROPN
bptjm-66	585	9	,	,	PUNCT
bptjm-66	585	10	et	et	PROPN
bptjm-66	585	11	al	al	PROPN
bptjm-66	585	12	.	.	PROPN
bptjm-66	585	13	phase	phase	PROPN
bptjm-66	585	14	ii	ii	PROPN
bptjm-66	585	15	clinical	clinical	ADJ
bptjm-66	585	16	trial	trial	NOUN
bptjm-66	585	17	of	of	ADP
bptjm-66	585	18	paclitaxel	paclitaxel	PROPN
bptjm-66	585	19	loaded	load	VERB
bptjm-66	585	20	polymeric	polymeric	ADJ
bptjm-66	585	21	micelle	micelle	NOUN
bptjm-66	585	22	in	in	ADP
bptjm-66	585	23	patients	patient	NOUN
bptjm-66	585	24	with	with	ADP
bptjm-66	585	25	advanced	advanced	ADJ
bptjm-66	585	26	pancreatic	pancreatic	ADJ
bptjm-66	585	27	cancer	cancer	NOUN
bptjm-66	585	28	.	.	PUNCT
bptjm-66	586	1	cancer	cancer	NOUN
bptjm-66	586	2	investigation	investigation	NOUN
bptjm-66	586	3	.	.	PUNCT
bptjm-66	587	1	2009;28(2):186	2009;28(2):186	PROPN
bptjm-66	587	2	-	-	PUNCT
bptjm-66	587	3	194	194	NUM
bptjm-66	587	4	.	.	PUNCT
bptjm-66	587	5	46	46	NUM
bptjm-66	587	6	.	.	PUNCT
bptjm-66	588	1	chis	chis	PROPN
bptjm-66	588	2	aa	aa	PROPN
bptjm-66	588	3	,	,	PUNCT
bptjm-66	588	4	dobrea	dobrea	PROPN
bptjm-66	588	5	c	c	PROPN
bptjm-66	588	6	,	,	PUNCT
bptjm-66	588	7	morgovan	morgovan	NOUN
bptjm-66	588	8	c	c	NOUN
bptjm-66	588	9	,	,	PUNCT
bptjm-66	588	10	et	et	PROPN
bptjm-66	588	11	al	al	PROPN
bptjm-66	588	12	.	.	PROPN
bptjm-66	588	13	applications	application	NOUN
bptjm-66	588	14	and	and	CCONJ
bptjm-66	588	15	limitations	limitation	NOUN
bptjm-66	588	16	of	of	ADP
bptjm-66	588	17	dendrimers	dendrimer	NOUN
bptjm-66	588	18	in	in	ADP
bptjm-66	588	19	biomedicine	biomedicine	NOUN
bptjm-66	588	20	.	.	PUNCT
bptjm-66	589	1	molecules	molecule	NOUN
bptjm-66	589	2	.	.	PUNCT
bptjm-66	590	1	2020;25(17):3982	2020;25(17):3982	NUM
bptjm-66	590	2	.	.	NOUN
bptjm-66	590	3	47	47	NUM
bptjm-66	590	4	.	.	PUNCT
bptjm-66	590	5	sustained	sustain	VERB
bptjm-66	590	6	-	-	PUNCT
bptjm-66	590	7	release	release	NOUN
bptjm-66	590	8	ketamine	ketamine	NOUN
bptjm-66	590	9	-	-	PUNCT
bptjm-66	590	10	loaded	load	VERB
bptjm-66	590	11	nanoparticles	nanoparticle	NOUN
bptjm-66	590	12	fabricated	fabricate	VERB
bptjm-66	590	13	by	by	ADP
bptjm-66	590	14	sequential	sequential	ADJ
bptjm-66	590	15	nanoprecipitation	nanoprecipitation	NOUN
bptjm-66	590	16	.	.	PUNCT
bptjm-66	591	1	international	international	ADJ
bptjm-66	591	2	journal	journal	PROPN
bptjm-66	591	3	of	of	ADP
bptjm-66	591	4	pharmaceutics	pharmaceutic	NOUN
bptjm-66	591	5	.	.	PUNCT
bptjm-66	592	1	2020;581:119291	2020;581:119291	NUM
bptjm-66	592	2	.	.	PUNCT
bptjm-66	593	1	berkeley	berkeley	PROPN
bptjm-66	593	2	pharma	pharma	PROPN
bptjm-66	593	3	tech	tech	PROPN
bptjm-66	593	4	journal	journal	NOUN
bptjm-66	593	5	of	of	ADP
bptjm-66	593	6	medicine	medicine	NOUN
bptjm-66	593	7	|	|	ADV
bptjm-66	593	8	33	33	NUM
bptjm-66	593	9	48	48	NUM
bptjm-66	593	10	.	.	PUNCT
bptjm-66	594	1	duncan	duncan	PROPN
bptjm-66	594	2	r.	r.	PROPN
bptjm-66	594	3	myofascial	myofascial	PROPN
bptjm-66	594	4	release	release	PROPN
bptjm-66	594	5	.	.	PUNCT
bptjm-66	595	1	human	human	ADJ
bptjm-66	595	2	kinetics	kinetic	NOUN
bptjm-66	595	3	;	;	PUNCT
bptjm-66	595	4	2021	2021	NUM
bptjm-66	595	5	.	.	PUNCT
bptjm-66	596	1	49	49	NUM
bptjm-66	596	2	.	.	PUNCT
bptjm-66	597	1	can	can	AUX
bptjm-66	597	2	myofascial	myofascial	ADJ
bptjm-66	597	3	release	release	NOUN
bptjm-66	597	4	relieve	relieve	VERB
bptjm-66	597	5	back	back	ADP
bptjm-66	597	6	pain	pain	NOUN
bptjm-66	597	7	?	?	PUNCT
bptjm-66	598	1	mayo	mayo	NOUN
bptjm-66	598	2	clinic	clinic	PROPN
bptjm-66	598	3	.	.	PUNCT
bptjm-66	599	1	50	50	NUM
bptjm-66	599	2	.	.	PUNCT
bptjm-66	599	3	liem	liem	PROPN
bptjm-66	599	4	t	t	PROPN
bptjm-66	599	5	,	,	PUNCT
bptjm-66	599	6	tozzi	tozzi	NOUN
bptjm-66	599	7	p	p	NOUN
bptjm-66	599	8	,	,	PUNCT
bptjm-66	599	9	chila	chila	NOUN
bptjm-66	599	10	a.	a.	NOUN
bptjm-66	599	11	fascia	fascia	NOUN
bptjm-66	599	12	in	in	ADP
bptjm-66	599	13	the	the	DET
bptjm-66	599	14	osteopathic	osteopathic	ADJ
bptjm-66	599	15	field	field	NOUN
bptjm-66	599	16	.	.	PUNCT
bptjm-66	600	1	jessica	jessica	PROPN
bptjm-66	600	2	kingsley	kingsley	PROPN
bptjm-66	600	3	publishers	publisher	NOUN
bptjm-66	600	4	;	;	PUNCT
bptjm-66	600	5	2017	2017	NUM
bptjm-66	600	6	.	.	PUNCT
bptjm-66	601	1	51	51	NUM
bptjm-66	601	2	.	.	PUNCT
bptjm-66	602	1	beardsley	beardsley	PROPN
bptjm-66	602	2	c	c	PROPN
bptjm-66	602	3	,	,	PUNCT
bptjm-66	602	4	škarabot	škarabot	PROPN
bptjm-66	602	5	j.	j.	PROPN
bptjm-66	602	6	effects	effect	NOUN
bptjm-66	602	7	of	of	ADP
bptjm-66	602	8	self	self	NOUN
bptjm-66	602	9	-	-	PUNCT
bptjm-66	602	10	myofascial	myofascial	ADJ
bptjm-66	602	11	release	release	NOUN
bptjm-66	602	12	:	:	PUNCT
bptjm-66	602	13	a	a	DET
bptjm-66	602	14	systematic	systematic	ADJ
bptjm-66	602	15	review	review	NOUN
bptjm-66	602	16	.	.	PUNCT
bptjm-66	603	1	journal	journal	PROPN
bptjm-66	603	2	of	of	ADP
bptjm-66	603	3	bodywork	bodywork	NOUN
bptjm-66	603	4	and	and	CCONJ
bptjm-66	603	5	movement	movement	NOUN
bptjm-66	603	6	therapies	therapy	NOUN
bptjm-66	603	7	.	.	PUNCT
bptjm-66	604	1	2015;19(4):747	2015;19(4):747	NUM
bptjm-66	604	2	-	-	SYM
bptjm-66	604	3	758	758	NUM
bptjm-66	604	4	.	.	PUNCT
bptjm-66	604	5	52	52	NUM
bptjm-66	604	6	.	.	PUNCT
bptjm-66	605	1	arguisuelas	arguisuelas	PROPN
bptjm-66	605	2	md	md	PROPN
bptjm-66	605	3	,	,	PUNCT
bptjm-66	605	4	lisón	lisón	VERB
bptjm-66	605	5	jf	jf	PROPN
bptjm-66	605	6	,	,	PUNCT
bptjm-66	605	7	sánchez	sánchez	NOUN
bptjm-66	605	8	-	-	PUNCT
bptjm-66	605	9	zuriaga	zuriaga	PROPN
bptjm-66	605	10	d	d	PROPN
bptjm-66	605	11	,	,	PUNCT
bptjm-66	605	12	martínez	martínez	NOUN
bptjm-66	605	13	-	-	PUNCT
bptjm-66	605	14	hurtado	hurtado	NOUN
bptjm-66	605	15	i	i	PROPN
bptjm-66	605	16	,	,	PUNCT
bptjm-66	605	17	doménech	doménech	NOUN
bptjm-66	605	18	-	-	PUNCT
bptjm-66	605	19	fernández	fernández	PROPN
bptjm-66	605	20	j.	j.	PROPN
bptjm-66	605	21	effects	effect	NOUN
bptjm-66	605	22	of	of	ADP
bptjm-66	605	23	myofascial	myofascial	ADJ
bptjm-66	605	24	release	release	NOUN
bptjm-66	605	25	in	in	ADP
bptjm-66	605	26	nonspecific	nonspecific	ADJ
bptjm-66	605	27	chronic	chronic	NOUN
bptjm-66	605	28	low	low	ADJ
bptjm-66	605	29	back	back	ADJ
bptjm-66	605	30	pain	pain	NOUN
bptjm-66	605	31	.	.	PUNCT
bptjm-66	606	1	spine	spine	NOUN
bptjm-66	606	2	.	.	PUNCT
bptjm-66	607	1	2017;42(9):627	2017;42(9):627	NUM
bptjm-66	607	2	-	-	PUNCT
bptjm-66	607	3	634	634	NUM
bptjm-66	607	4	.	.	PUNCT
bptjm-66	608	1	53	53	NUM
bptjm-66	608	2	.	.	PUNCT
bptjm-66	609	1	jones	jones	PROPN
bptjm-66	609	2	i	i	PROPN
bptjm-66	609	3	,	,	PUNCT
bptjm-66	609	4	johnson	johnson	PROPN
bptjm-66	609	5	mi	mi	PROPN
bptjm-66	609	6	.	.	PROPN
bptjm-66	609	7	transcutaneous	transcutaneous	ADJ
bptjm-66	609	8	electrical	electrical	ADJ
bptjm-66	609	9	nerve	nerve	NOUN
bptjm-66	609	10	stimulation	stimulation	NOUN
bptjm-66	609	11	.	.	PUNCT
bptjm-66	610	1	continuing	continue	VERB
bptjm-66	610	2	education	education	NOUN
bptjm-66	610	3	in	in	ADP
bptjm-66	610	4	anaesthesia	anaesthesia	PROPN
bptjm-66	610	5	critical	critical	ADJ
bptjm-66	610	6	care	care	NOUN
bptjm-66	610	7	&	&	CCONJ
bptjm-66	610	8	pain	pain	NOUN
bptjm-66	610	9	.	.	PUNCT
bptjm-66	611	1	2009;9(4):130	2009;9(4):130	NUM
bptjm-66	611	2	-	-	SYM
bptjm-66	611	3	135	135	NUM
bptjm-66	611	4	.	.	PUNCT
bptjm-66	612	1	54	54	NUM
bptjm-66	612	2	.	.	PUNCT
bptjm-66	613	1	teoli	teoli	PROPN
bptjm-66	613	2	d	d	PROPN
bptjm-66	613	3	,	,	PUNCT
bptjm-66	613	4	an	an	DET
bptjm-66	613	5	j.	j.	PROPN
bptjm-66	613	6	transcutaneous	transcutaneous	ADJ
bptjm-66	613	7	electrical	electrical	ADJ
bptjm-66	613	8	nerve	nerve	NOUN
bptjm-66	613	9	stimulation	stimulation	NOUN
bptjm-66	613	10	(	(	PUNCT
bptjm-66	613	11	tens	ten	NOUN
bptjm-66	613	12	)	)	PUNCT
bptjm-66	613	13	.	.	PUNCT
bptjm-66	614	1	nih.gov	nih.gov	NOUN
bptjm-66	614	2	.	.	PUNCT
bptjm-66	615	1	published	publish	VERB
bptjm-66	615	2	june	june	PROPN
bptjm-66	615	3	28	28	NUM
bptjm-66	615	4	,	,	PUNCT
bptjm-66	615	5	2019	2019	NUM
bptjm-66	615	6	.	.	PUNCT
bptjm-66	616	1	55	55	NUM
bptjm-66	616	2	.	.	PUNCT
bptjm-66	617	1	johnson	johnson	PROPN
bptjm-66	617	2	m.	m.	PROPN
bptjm-66	617	3	transcutaneous	transcutaneous	ADJ
bptjm-66	617	4	electrical	electrical	ADJ
bptjm-66	617	5	nerve	nerve	NOUN
bptjm-66	617	6	stimulation	stimulation	NOUN
bptjm-66	617	7	:	:	PUNCT
bptjm-66	618	1	mechanisms	mechanism	NOUN
bptjm-66	618	2	,	,	PUNCT
bptjm-66	618	3	clinical	clinical	ADJ
bptjm-66	618	4	application	application	NOUN
bptjm-66	618	5	and	and	CCONJ
bptjm-66	618	6	evidence	evidence	NOUN
bptjm-66	618	7	.	.	PUNCT
bptjm-66	619	1	reviews	review	NOUN
bptjm-66	619	2	in	in	ADP
bptjm-66	619	3	pain	pain	NOUN
bptjm-66	619	4	.	.	PUNCT
bptjm-66	620	1	2007;1(1):7	2007;1(1):7	NOUN
bptjm-66	620	2	-	-	PUNCT
bptjm-66	620	3	11	11	NUM
bptjm-66	620	4	.	.	PUNCT
bptjm-66	621	1	56	56	NUM
bptjm-66	621	2	.	.	PUNCT
bptjm-66	622	1	felix	felix	PROPN
bptjm-66	622	2	e	e	PROPN
bptjm-66	622	3	,	,	PUNCT
bptjm-66	622	4	university	university	PROPN
bptjm-66	622	5	of	of	ADP
bptjm-66	622	6	miami	miami	PROPN
bptjm-66	622	7	,	,	PUNCT
bptjm-66	622	8	national	national	PROPN
bptjm-66	622	9	institute	institute	PROPN
bptjm-66	622	10	on	on	ADP
bptjm-66	622	11	disability	disability	NOUN
bptjm-66	622	12	,	,	PUNCT
bptjm-66	622	13	independent	independent	ADJ
bptjm-66	622	14	living	living	NOUN
bptjm-66	622	15	,	,	PUNCT
bptjm-66	622	16	and	and	CCONJ
bptjm-66	622	17	rehabilitation	rehabilitation	NOUN
bptjm-66	622	18	research	research	NOUN
bptjm-66	622	19	.	.	PUNCT
bptjm-66	623	1	randomized	randomize	VERB
bptjm-66	623	2	,	,	PUNCT
bptjm-66	623	3	double	double	ADJ
bptjm-66	623	4	-	-	PUNCT
bptjm-66	623	5	blinded	blind	VERB
bptjm-66	623	6	,	,	PUNCT
bptjm-66	623	7	controlled	control	VERB
bptjm-66	623	8	trial	trial	NOUN
bptjm-66	623	9	of	of	ADP
bptjm-66	623	10	early	early	ADJ
bptjm-66	623	11	-	-	PUNCT
bptjm-66	623	12	intervention	intervention	NOUN
bptjm-66	623	13	tens	ten	NOUN
bptjm-66	623	14	for	for	ADP
bptjm-66	623	15	the	the	DET
bptjm-66	623	16	reduction	reduction	NOUN
bptjm-66	623	17	of	of	ADP
bptjm-66	623	18	the	the	DET
bptjm-66	623	19	prevalence	prevalence	NOUN
bptjm-66	623	20	and	and	CCONJ
bptjm-66	623	21	severity	severity	NOUN
bptjm-66	623	22	of	of	ADP
bptjm-66	623	23	chronic	chronic	ADJ
bptjm-66	623	24	neuropathic	neuropathic	ADJ
bptjm-66	623	25	pain	pain	NOUN
bptjm-66	623	26	during	during	ADP
bptjm-66	623	27	the	the	DET
bptjm-66	623	28	first	first	ADJ
bptjm-66	623	29	year	year	NOUN
bptjm-66	623	30	after	after	ADP
bptjm-66	623	31	spinal	spinal	PROPN
bptjm-66	623	32	cord	cord	NOUN
bptjm-66	623	33	injury	injury	NOUN
bptjm-66	623	34	.	.	PUNCT
bptjm-66	624	1	clinicaltrials.gov	clinicaltrials.gov	X
bptjm-66	624	2	.	.	NOUN
bptjm-66	624	3	57	57	NUM
bptjm-66	624	4	.	.	X
bptjm-66	625	1	de	de	AUX
bptjm-66	625	2	oliveira	oliveira	PROPN
bptjm-66	625	3	mf	mf	PROPN
bptjm-66	625	4	,	,	PUNCT
bptjm-66	625	5	johnson	johnson	PROPN
bptjm-66	625	6	ds	ds	PROPN
bptjm-66	625	7	,	,	PUNCT
bptjm-66	625	8	demchak	demchak	PROPN
bptjm-66	625	9	t	t	PROPN
bptjm-66	625	10	,	,	PUNCT
bptjm-66	625	11	tomazoni	tomazoni	PROPN
bptjm-66	625	12	ss	ss	PROPN
bptjm-66	625	13	,	,	PUNCT
bptjm-66	625	14	leal	leal	ADJ
bptjm-66	625	15	-	-	PUNCT
bptjm-66	625	16	junior	junior	ADJ
bptjm-66	625	17	ec	ec	PROPN
bptjm-66	625	18	.	.	PUNCT
bptjm-66	626	1	low	low	ADJ
bptjm-66	626	2	-	-	PUNCT
bptjm-66	626	3	intensity	intensity	NOUN
bptjm-66	626	4	laser	laser	NOUN
bptjm-66	626	5	and	and	CCONJ
bptjm-66	626	6	led	lead	VERB
bptjm-66	626	7	(	(	PUNCT
bptjm-66	626	8	photobiomodulation	photobiomodulation	NOUN
bptjm-66	626	9	therapy	therapy	NOUN
bptjm-66	626	10	)	)	PUNCT
bptjm-66	626	11	for	for	ADP
bptjm-66	626	12	pain	pain	NOUN
bptjm-66	626	13	control	control	NOUN
bptjm-66	626	14	of	of	ADP
bptjm-66	626	15	the	the	DET
bptjm-66	626	16	most	most	ADV
bptjm-66	626	17	common	common	ADJ
bptjm-66	626	18	musculoskeletal	musculoskeletal	ADJ
bptjm-66	626	19	conditions	condition	NOUN
bptjm-66	626	20	.	.	PUNCT
bptjm-66	627	1	european	european	ADJ
bptjm-66	627	2	journal	journal	PROPN
bptjm-66	627	3	of	of	ADP
bptjm-66	627	4	physical	physical	ADJ
bptjm-66	627	5	and	and	CCONJ
bptjm-66	627	6	rehabilitation	rehabilitation	NOUN
bptjm-66	627	7	medicine	medicine	NOUN
bptjm-66	627	8	.	.	PUNCT
bptjm-66	628	1	2022;58(2	2022;58(2	NUM
bptjm-66	628	2	)	)	PUNCT
bptjm-66	628	3	.	.	PUNCT
bptjm-66	629	1	58	58	NUM
bptjm-66	629	2	.	.	PUNCT
bptjm-66	630	1	friedmann	friedmann	PROPN
bptjm-66	630	2	h	h	PROPN
bptjm-66	630	3	,	,	PUNCT
bptjm-66	630	4	lipovsky	lipovsky	NOUN
bptjm-66	630	5	a	a	NOUN
bptjm-66	630	6	,	,	PUNCT
bptjm-66	630	7	nitzan	nitzan	NOUN
bptjm-66	630	8	y	y	PROPN
bptjm-66	630	9	,	,	PUNCT
bptjm-66	630	10	lubart	lubart	PROPN
bptjm-66	630	11	r.	r.	PROPN
bptjm-66	630	12	combined	combined	PROPN
bptjm-66	630	13	magnetic	magnetic	PROPN
bptjm-66	630	14	and	and	CCONJ
bptjm-66	630	15	pulsed	pulse	VERB
bptjm-66	630	16	laser	laser	NOUN
bptjm-66	630	17	fields	field	NOUN
bptjm-66	630	18	produce	produce	VERB
bptjm-66	630	19	synergistic	synergistic	ADJ
bptjm-66	630	20	acceleration	acceleration	NOUN
bptjm-66	630	21	of	of	ADP
bptjm-66	630	22	cellular	cellular	ADJ
bptjm-66	630	23	electron	electron	NOUN
bptjm-66	630	24	transfer	transfer	NOUN
bptjm-66	630	25	.	.	PUNCT
bptjm-66	631	1	laser	laser	NOUN
bptjm-66	631	2	therapy	therapy	NOUN
bptjm-66	631	3	.	.	PUNCT
bptjm-66	632	1	2009;18(3):137	2009;18(3):137	NUM
bptjm-66	632	2	-	-	SYM
bptjm-66	632	3	141	141	NUM
bptjm-66	632	4	.	.	PUNCT
bptjm-66	633	1	59	59	NUM
bptjm-66	633	2	.	.	X
bptjm-66	633	3	de	de	PROPN
bptjm-66	633	4	freitas	freitas	PROPN
bptjm-66	633	5	lf	lf	PROPN
bptjm-66	633	6	,	,	PUNCT
bptjm-66	633	7	hamblin	hamblin	PROPN
bptjm-66	633	8	mr	mr	PROPN
bptjm-66	633	9	.	.	PROPN
bptjm-66	633	10	proposed	propose	VERB
bptjm-66	633	11	mechanisms	mechanism	NOUN
bptjm-66	633	12	of	of	ADP
bptjm-66	633	13	photobiomodulation	photobiomodulation	NOUN
bptjm-66	633	14	or	or	CCONJ
bptjm-66	633	15	low	low	ADJ
bptjm-66	633	16	-	-	PUNCT
bptjm-66	633	17	level	level	NOUN
bptjm-66	633	18	light	light	NOUN
bptjm-66	633	19	therapy	therapy	NOUN
bptjm-66	633	20	.	.	PUNCT
bptjm-66	634	1	ieee	ieee	PROPN
bptjm-66	634	2	journal	journal	PROPN
bptjm-66	634	3	of	of	ADP
bptjm-66	634	4	selected	select	VERB
bptjm-66	634	5	topics	topic	NOUN
bptjm-66	634	6	in	in	ADP
bptjm-66	634	7	quantum	quantum	ADJ
bptjm-66	634	8	electronics	electronic	NOUN
bptjm-66	634	9	.	.	PUNCT
bptjm-66	635	1	2016;22(3):348	2016;22(3):348	NUM
bptjm-66	635	2	-	-	PUNCT
bptjm-66	635	3	364	364	NUM
bptjm-66	635	4	.	.	PUNCT
bptjm-66	635	5	60	60	NUM
bptjm-66	635	6	.	.	PUNCT
bptjm-66	636	1	toich	toich	PROPN
bptjm-66	636	2	s.	s.	PROPN
bptjm-66	636	3	photobiomodulation	photobiomodulation	PROPN
bptjm-66	636	4	:	:	PUNCT
bptjm-66	636	5	light	light	ADJ
bptjm-66	636	6	-	-	PUNCT
bptjm-66	636	7	tissue	tissue	NOUN
bptjm-66	636	8	interaction	interaction	NOUN
bptjm-66	636	9	,	,	PUNCT
bptjm-66	636	10	and	and	CCONJ
bptjm-66	636	11	the	the	DET
bptjm-66	636	12	current	current	ADJ
bptjm-66	636	13	and	and	CCONJ
bptjm-66	636	14	future	future	ADJ
bptjm-66	636	15	states	state	NOUN
bptjm-66	636	16	of	of	ADP
bptjm-66	636	17	pbm	pbm	NOUN
bptjm-66	636	18	.	.	PUNCT
bptjm-66	637	1	www.lumitex.com	www.lumitex.com	PROPN
bptjm-66	637	2	.	.	PROPN
bptjm-66	638	1	61	61	NUM
bptjm-66	638	2	.	.	PUNCT
bptjm-66	638	3	gendron	gendron	PROPN
bptjm-66	638	4	dj	dj	PROPN
bptjm-66	638	5	,	,	PUNCT
bptjm-66	638	6	hamblin	hamblin	PROPN
bptjm-66	638	7	mr	mr	PROPN
bptjm-66	638	8	.	.	PROPN
bptjm-66	638	9	applications	application	NOUN
bptjm-66	638	10	of	of	ADP
bptjm-66	638	11	photobiomodulation	photobiomodulation	NOUN
bptjm-66	638	12	therapy	therapy	NOUN
bptjm-66	638	13	to	to	ADP
bptjm-66	638	14	musculoskeletal	musculoskeletal	ADJ
bptjm-66	638	15	disorders	disorder	NOUN
bptjm-66	638	16	and	and	CCONJ
bptjm-66	638	17	osteoarthritis	osteoarthritis	NOUN
bptjm-66	638	18	with	with	ADP
bptjm-66	638	19	particular	particular	ADJ
bptjm-66	638	20	relevance	relevance	NOUN
bptjm-66	638	21	to	to	ADP
bptjm-66	638	22	canada	canada	PROPN
bptjm-66	638	23	.	.	PUNCT
bptjm-66	639	1	photobiomodulation	photobiomodulation	NOUN
bptjm-66	639	2	,	,	PUNCT
bptjm-66	639	3	photomedicine	photomedicine	NOUN
bptjm-66	639	4	,	,	PUNCT
bptjm-66	639	5	and	and	CCONJ
bptjm-66	639	6	laser	laser	NOUN
bptjm-66	639	7	surgery	surgery	NOUN
bptjm-66	639	8	.	.	PUNCT
bptjm-66	640	1	2019;37(7):408	2019;37(7):408	PROPN
bptjm-66	640	2	-	-	SYM
bptjm-66	640	3	420	420	NUM
bptjm-66	640	4	.	.	PUNCT
bptjm-66	641	1	62	62	NUM
bptjm-66	641	2	.	.	PUNCT
bptjm-66	642	1	arora	arora	PROPN
bptjm-66	642	2	v	v	PROPN
bptjm-66	642	3	,	,	PUNCT
bptjm-66	642	4	campbell	campbell	PROPN
bptjm-66	642	5	jn	jn	PROPN
bptjm-66	642	6	,	,	PUNCT
bptjm-66	642	7	chung	chung	PROPN
bptjm-66	642	8	mk	mk	PROPN
bptjm-66	642	9	.	.	PUNCT
bptjm-66	643	1	fight	fight	VERB
bptjm-66	643	2	fire	fire	NOUN
bptjm-66	643	3	with	with	ADP
bptjm-66	643	4	fire	fire	NOUN
bptjm-66	643	5	:	:	PUNCT
bptjm-66	643	6	neurobiology	neurobiology	NOUN
bptjm-66	643	7	of	of	ADP
bptjm-66	643	8	capsaicin	capsaicin	NOUN
bptjm-66	643	9	-	-	PUNCT
bptjm-66	643	10	induced	induce	VERB
bptjm-66	643	11	analgesia	analgesia	NOUN
bptjm-66	643	12	for	for	ADP
bptjm-66	643	13	chronic	chronic	ADJ
bptjm-66	643	14	pain	pain	NOUN
bptjm-66	643	15	.	.	PUNCT
bptjm-66	644	1	pharmacology	pharmacology	NOUN
bptjm-66	644	2	&	&	CCONJ
bptjm-66	644	3	therapeutics	therapeutic	NOUN
bptjm-66	644	4	.	.	PUNCT
bptjm-66	645	1	2021;220:107743	2021;220:107743	NUM
bptjm-66	645	2	.	.	PUNCT
bptjm-66	646	1	63	63	NUM
bptjm-66	646	2	.	.	PUNCT
bptjm-66	646	3	brown	brown	PROPN
bptjm-66	646	4	,	,	PUNCT
bptjm-66	646	5	s.	s.	PROPN
bptjm-66	646	6	,	,	PUNCT
bptjm-66	646	7	simpson	simpson	PROPN
bptjm-66	646	8	,	,	PUNCT
bptjm-66	646	9	d.m	d.m	PROPN
bptjm-66	646	10	.	.	PROPN
bptjm-66	646	11	,	,	PUNCT
bptjm-66	646	12	moyle	moyle	PROPN
bptjm-66	646	13	,	,	PUNCT
bptjm-66	646	14	g.	g.	PROPN
bptjm-66	646	15	et	et	PROPN
bptjm-66	646	16	al	al	PROPN
bptjm-66	646	17	.	.	PROPN
bptjm-66	646	18	ngx-4010	ngx-4010	PROPN
bptjm-66	646	19	,	,	PUNCT
bptjm-66	646	20	a	a	DET
bptjm-66	646	21	capsaicin	capsaicin	NOUN
bptjm-66	646	22	8	8	NUM
bptjm-66	646	23	%	%	NOUN
bptjm-66	646	24	patch	patch	NOUN
bptjm-66	646	25	,	,	PUNCT
bptjm-66	646	26	for	for	ADP
bptjm-66	646	27	the	the	DET
bptjm-66	646	28	treatment	treatment	NOUN
bptjm-66	646	29	of	of	ADP
bptjm-66	646	30	painful	painful	ADJ
bptjm-66	646	31	hiv	hiv	PROPN
bptjm-66	646	32	-	-	PUNCT
bptjm-66	646	33	associated	associate	VERB
bptjm-66	646	34	distal	distal	PROPN
bptjm-66	646	35	berkeley	berkeley	PROPN
bptjm-66	646	36	pharma	pharma	PROPN
bptjm-66	646	37	tech	tech	NOUN
bptjm-66	646	38	journal	journal	NOUN
bptjm-66	646	39	of	of	ADP
bptjm-66	646	40	medicine	medicine	NOUN
bptjm-66	647	1	|	|	ADV
bptjm-66	647	2	34	34	NUM
bptjm-66	647	3	http://nih.gov	http://nih.gov	VERB
bptjm-66	647	4	sensory	sensory	ADJ
bptjm-66	647	5	polyneuropathy	polyneuropathy	NOUN
bptjm-66	647	6	:	:	PUNCT
bptjm-66	647	7	integrated	integrate	VERB
bptjm-66	647	8	analysis	analysis	NOUN
bptjm-66	647	9	of	of	ADP
bptjm-66	647	10	two	two	NUM
bptjm-66	647	11	phase	phase	NOUN
bptjm-66	647	12	iii	iii	NOUN
bptjm-66	647	13	,	,	PUNCT
bptjm-66	647	14	randomized	randomize	VERB
bptjm-66	647	15	,	,	PUNCT
bptjm-66	647	16	controlled	control	VERB
bptjm-66	647	17	trials	trial	NOUN
bptjm-66	647	18	.	.	PUNCT
bptjm-66	648	1	aids	aids	PROPN
bptjm-66	648	2	res	re	NOUN
bptjm-66	648	3	ther	ther	ADV
bptjm-66	648	4	10	10	NUM
bptjm-66	648	5	,	,	PUNCT
bptjm-66	648	6	5	5	NUM
bptjm-66	648	7	(	(	PUNCT
bptjm-66	648	8	2013	2013	NUM
bptjm-66	648	9	)	)	PUNCT
bptjm-66	648	10	.	.	PUNCT
bptjm-66	649	1	64	64	NUM
bptjm-66	649	2	.	.	PUNCT
bptjm-66	650	1	hussain	hussain	PROPN
bptjm-66	650	2	n	n	CCONJ
bptjm-66	650	3	,	,	PUNCT
bptjm-66	650	4	amira	amira	PROPN
bptjm-66	650	5	s.a	s.a	PROPN
bptjm-66	650	6	.	.	PROPN
bptjm-66	650	7	said	say	VERB
bptjm-66	650	8	,	,	PUNCT
bptjm-66	650	9	javaid	javaid	PROPN
bptjm-66	650	10	fa	fa	PROPN
bptjm-66	650	11	,	,	PUNCT
bptjm-66	650	12	et	et	PROPN
bptjm-66	650	13	al	al	PROPN
bptjm-66	650	14	.	.	PUNCT
bptjm-66	651	1	the	the	DET
bptjm-66	651	2	efficacy	efficacy	NOUN
bptjm-66	651	3	and	and	CCONJ
bptjm-66	651	4	safety	safety	NOUN
bptjm-66	651	5	profile	profile	NOUN
bptjm-66	651	6	of	of	ADP
bptjm-66	651	7	capsaicin	capsaicin	NOUN
bptjm-66	651	8	8	8	NUM
bptjm-66	651	9	%	%	NOUN
bptjm-66	651	10	patch	patch	NOUN
bptjm-66	651	11	versus	versus	ADP
bptjm-66	651	12	5	5	NUM
bptjm-66	651	13	%	%	NOUN
bptjm-66	651	14	lidocaine	lidocaine	NOUN
bptjm-66	651	15	patch	patch	NOUN
bptjm-66	651	16	in	in	ADP
bptjm-66	651	17	patients	patient	NOUN
bptjm-66	651	18	with	with	ADP
bptjm-66	651	19	diabetic	diabetic	ADJ
bptjm-66	651	20	peripheral	peripheral	ADJ
bptjm-66	651	21	neuropathic	neuropathic	ADJ
bptjm-66	651	22	pain	pain	NOUN
bptjm-66	651	23	:	:	PUNCT
bptjm-66	651	24	a	a	DET
bptjm-66	651	25	randomized	randomized	ADJ
bptjm-66	651	26	,	,	PUNCT
bptjm-66	651	27	placebo	placebo	NOUN
bptjm-66	651	28	-	-	PUNCT
bptjm-66	651	29	controlled	control	VERB
bptjm-66	651	30	study	study	NOUN
bptjm-66	651	31	of	of	ADP
bptjm-66	651	32	south	south	ADJ
bptjm-66	651	33	asian	asian	ADJ
bptjm-66	651	34	male	male	ADJ
bptjm-66	651	35	patients	patient	NOUN
bptjm-66	651	36	.	.	PUNCT
bptjm-66	652	1	journal	journal	NOUN
bptjm-66	652	2	of	of	ADP
bptjm-66	652	3	diabetes	diabetes	NOUN
bptjm-66	652	4	and	and	CCONJ
bptjm-66	652	5	metabolic	metabolic	NOUN
bptjm-66	652	6	disorders	disorder	NOUN
bptjm-66	652	7	.	.	PUNCT
bptjm-66	653	1	2021;20(1):271	2021;20(1):271	NOUN
bptjm-66	653	2	-	-	PUNCT
bptjm-66	653	3	278	278	NUM
bptjm-66	653	4	.	.	PUNCT
bptjm-66	654	1	berkeley	berkeley	PROPN
bptjm-66	654	2	pharma	pharma	PROPN
bptjm-66	654	3	tech	tech	PROPN
bptjm-66	654	4	journal	journal	NOUN
bptjm-66	654	5	of	of	ADP
bptjm-66	654	6	medicine	medicine	NOUN
bptjm-66	654	7	|	|	ADV
bptjm-66	654	8	35	35	NUM