id	sid	tid	token	lemma	pos
bionys-568	1	1	al	al	PROPN
bionys-568	1	2	-	-	PUNCT
bionys-568	1	3	khaykanee	khaykanee	PROPN
bionys-568	1	4	et	et	PROPN
bionys-568	1	5	al	al	PROPN
bionys-568	1	6	.	.	PROPN
bionys-568	1	7	2025	2025	NUM
bionys-568	1	8	,	,	PUNCT
bionys-568	1	9	biologica	biologica	PROPN
bionys-568	1	10	nyssana	nyssana	PROPN
bionys-568	1	11	16(1	16(1	PROPN
bionys-568	1	12	)	)	PUNCT
bionys-568	1	13	287	287	NUM
bionys-568	1	14	16	16	NUM
bionys-568	1	15	(	(	PUNCT
bionys-568	1	16	1	1	NUM
bionys-568	1	17	)	)	PUNCT
bionys-568	1	18	june	june	PROPN
bionys-568	1	19	2025	2025	NUM
bionys-568	1	20	:	:	PUNCT
bionys-568	1	21	287	287	NUM
bionys-568	1	22	-	-	SYM
bionys-568	1	23	296	296	NUM
bionys-568	1	24	doi	doi	NOUN
bionys-568	1	25	:	:	PUNCT
bionys-568	1	26	10.46793	10.46793	NUM
bionys-568	1	27	/	/	SYM
bionys-568	1	28	biolnyss.16.1.15a	biolnyss.16.1.15a	PROPN
bionys-568	1	29	role	role	NOUN
bionys-568	1	30	of	of	ADP
bionys-568	1	31	11β	11β	PROPN
bionys-568	1	32	-	-	PUNCT
bionys-568	1	33	hydroxysteroid	hydroxysteroid	VERB
bionys-568	1	34	dehydrogenase	dehydrogenase	NOUN
bionys-568	1	35	gene	gene	NOUN
bionys-568	1	36	polymorphisms	polymorphism	NOUN
bionys-568	1	37	rs846910	rs846910	NOUN
bionys-568	1	38	and	and	CCONJ
bionys-568	1	39	rs12086634	rs12086634	PROPN
bionys-568	1	40	in	in	ADP
bionys-568	1	41	the	the	DET
bionys-568	1	42	etiology	etiology	NOUN
bionys-568	1	43	of	of	ADP
bionys-568	1	44	hepatocellular	hepatocellular	ADJ
bionys-568	1	45	carcinoma	carcinoma	NOUN
bionys-568	1	46	original	original	ADJ
bionys-568	1	47	article	article	NOUN
bionys-568	1	48	ahmed	ahme	VERB
bionys-568	1	49	mudher	mudher	PROPN
bionys-568	1	50	al	al	PROPN
bionys-568	1	51	-	-	PUNCT
bionys-568	1	52	khaykanee	khaykanee	PROPN
bionys-568	1	53	general	general	ADJ
bionys-568	1	54	directorate	directorate	NOUN
bionys-568	1	55	of	of	ADP
bionys-568	1	56	education	education	NOUN
bionys-568	1	57	of	of	ADP
bionys-568	1	58	babylon	babylon	PROPN
bionys-568	1	59	governorate	governorate	PROPN
bionys-568	1	60	,	,	PUNCT
bionys-568	1	61	iraq	iraq	PROPN
bionys-568	1	62	ahmedmudher14@gmail.com	ahmedmudher14@gmail.com	X
bionys-568	1	63	(	(	PUNCT
bionys-568	1	64	corresponding	corresponding	ADJ
bionys-568	1	65	author	author	NOUN
bionys-568	1	66	)	)	PUNCT
bionys-568	1	67	soura	soura	PROPN
bionys-568	1	68	alaa	alaa	PROPN
bionys-568	1	69	hussein	hussein	PROPN
bionys-568	1	70	department	department	PROPN
bionys-568	1	71	of	of	ADP
bionys-568	1	72	technical	technical	ADJ
bionys-568	1	73	nursing	nursing	NOUN
bionys-568	1	74	,	,	PUNCT
bionys-568	1	75	technical	technical	PROPN
bionys-568	1	76	institute	institute	PROPN
bionys-568	1	77	-	-	PUNCT
bionys-568	1	78	baghdad	baghdad	PROPN
bionys-568	1	79	,	,	PUNCT
bionys-568	1	80	middle	middle	PROPN
bionys-568	1	81	technical	technical	PROPN
bionys-568	1	82	university	university	PROPN
bionys-568	1	83	,	,	PUNCT
bionys-568	1	84	10074	10074	NUM
bionys-568	1	85	,	,	PUNCT
bionys-568	1	86	iraq	iraq	PROPN
bionys-568	1	87	z	z	PROPN
bionys-568	1	88	muhsen	muhsen	PROPN
bionys-568	1	89	m	m	PROPN
bionys-568	1	90	ali	ali	PROPN
bionys-568	1	91	department	department	PROPN
bionys-568	1	92	of	of	ADP
bionys-568	1	93	technical	technical	PROPN
bionys-568	1	94	anesthesia	anesthesia	PROPN
bionys-568	1	95	technical	technical	PROPN
bionys-568	1	96	institute	institute	PROPN
bionys-568	1	97	-	-	PUNCT
bionys-568	1	98	baghdad	baghdad	PROPN
bionys-568	1	99	,	,	PUNCT
bionys-568	1	100	middle	middle	PROPN
bionys-568	1	101	technical	technical	PROPN
bionys-568	1	102	university	university	PROPN
bionys-568	1	103	,	,	PUNCT
bionys-568	1	104	10074	10074	NUM
bionys-568	1	105	,	,	PUNCT
bionys-568	1	106	iraq	iraq	PROPN
bionys-568	1	107	received	receive	VERB
bionys-568	1	108	:	:	PUNCT
bionys-568	1	109	december	december	PROPN
bionys-568	1	110	06	06	NUM
bionys-568	1	111	,	,	PUNCT
bionys-568	1	112	2024	2024	NUM
bionys-568	1	113	revised	revise	VERB
bionys-568	1	114	:	:	PUNCT
bionys-568	1	115	february	february	PROPN
bionys-568	1	116	17	17	NUM
bionys-568	1	117	,	,	PUNCT
bionys-568	1	118	2025	2025	NUM
bionys-568	1	119	accepted	accept	VERB
bionys-568	1	120	:	:	PUNCT
bionys-568	1	121	march	march	PROPN
bionys-568	1	122	17	17	NUM
bionys-568	1	123	,	,	PUNCT
bionys-568	1	124	2025	2025	NUM
bionys-568	1	125	abstract	abstract	NOUN
bionys-568	1	126	:	:	PUNCT
bionys-568	1	127	in	in	ADP
bionys-568	1	128	asia	asia	PROPN
bionys-568	1	129	,	,	PUNCT
bionys-568	1	130	the	the	DET
bionys-568	1	131	most	most	ADV
bionys-568	1	132	frequent	frequent	ADJ
bionys-568	1	133	cause	cause	NOUN
bionys-568	1	134	of	of	ADP
bionys-568	1	135	hepatocellular	hepatocellular	ADJ
bionys-568	1	136	carcinoma	carcinoma	NOUN
bionys-568	1	137	(	(	PUNCT
bionys-568	1	138	hcc	hcc	PROPN
bionys-568	1	139	)	)	PUNCT
bionys-568	1	140	is	be	AUX
bionys-568	1	141	chronic	chronic	ADJ
bionys-568	1	142	hepatitis	hepatitis	PROPN
bionys-568	1	143	b.	b.	PROPN
bionys-568	2	1	the	the	DET
bionys-568	2	2	hepatitis	hepatitis	PROPN
bionys-568	2	3	b	b	PROPN
bionys-568	2	4	virus	virus	PROPN
bionys-568	2	5	's	's	PART
bionys-568	2	6	(	(	PUNCT
bionys-568	2	7	hbv	hbv	NOUN
bionys-568	2	8	)	)	PUNCT
bionys-568	2	9	genomic	genomic	NOUN
bionys-568	2	10	integration	integration	NOUN
bionys-568	2	11	is	be	AUX
bionys-568	2	12	probably	probably	ADV
bionys-568	2	13	a	a	DET
bionys-568	2	14	precursor	precursor	NOUN
bionys-568	2	15	to	to	ADP
bionys-568	2	16	carcinogenesis	carcinogenesis	NOUN
bionys-568	2	17	.	.	PUNCT
bionys-568	3	1	the	the	DET
bionys-568	3	2	integrated	integrate	VERB
bionys-568	3	3	hbv	hbv	NOUN
bionys-568	3	4	genome	genome	NOUN
bionys-568	3	5	may	may	AUX
bionys-568	3	6	directly	directly	ADV
bionys-568	3	7	activate	activate	VERB
bionys-568	3	8	nearby	nearby	ADJ
bionys-568	3	9	cellular	cellular	ADJ
bionys-568	3	10	genes	gene	NOUN
bionys-568	3	11	to	to	PART
bionys-568	3	12	give	give	VERB
bionys-568	3	13	the	the	DET
bionys-568	3	14	liver	liver	NOUN
bionys-568	3	15	cells	cell	NOUN
bionys-568	3	16	a	a	DET
bionys-568	3	17	selective	selective	ADJ
bionys-568	3	18	growth	growth	NOUN
bionys-568	3	19	advantage	advantage	NOUN
bionys-568	3	20	.	.	PUNCT
bionys-568	4	1	our	our	PRON
bionys-568	4	2	study	study	NOUN
bionys-568	4	3	's	's	PART
bionys-568	4	4	goal	goal	NOUN
bionys-568	4	5	was	be	AUX
bionys-568	4	6	to	to	PART
bionys-568	4	7	determine	determine	VERB
bionys-568	4	8	if	if	SCONJ
bionys-568	4	9	genetic	genetic	ADJ
bionys-568	4	10	variants	variant	NOUN
bionys-568	4	11	in	in	ADP
bionys-568	4	12	11β	11β	NOUN
bionys-568	4	13	-	-	PUNCT
bionys-568	4	14	hsd1	hsd1	PROPN
bionys-568	4	15	,	,	PUNCT
bionys-568	4	16	rs846910	rs846910	NOUN
bionys-568	4	17	and	and	CCONJ
bionys-568	4	18	rs12086634	rs12086634	PROPN
bionys-568	4	19	could	could	AUX
bionys-568	4	20	be	be	AUX
bionys-568	4	21	linked	link	VERB
bionys-568	4	22	to	to	ADP
bionys-568	4	23	chronic	chronic	ADJ
bionys-568	4	24	hepatitis	hepatitis	PROPN
bionys-568	4	25	b	b	PROPN
bionys-568	4	26	virus	virus	NOUN
bionys-568	4	27	(	(	PUNCT
bionys-568	4	28	hbv	hbv	NOUN
bionys-568	4	29	)	)	PUNCT
bionys-568	4	30	infection	infection	NOUN
bionys-568	4	31	and	and	CCONJ
bionys-568	4	32	hepatocellular	hepatocellular	ADJ
bionys-568	4	33	carcinoma	carcinoma	NOUN
bionys-568	4	34	(	(	PUNCT
bionys-568	4	35	hcc	hcc	PROPN
bionys-568	4	36	)	)	PUNCT
bionys-568	4	37	.	.	PUNCT
bionys-568	5	1	150	150	NUM
bionys-568	5	2	samples	sample	NOUN
bionys-568	5	3	were	be	AUX
bionys-568	5	4	collected	collect	VERB
bionys-568	5	5	from	from	ADP
bionys-568	5	6	people	people	NOUN
bionys-568	5	7	suffering	suffer	VERB
bionys-568	5	8	from	from	ADP
bionys-568	5	9	hepatitis	hepatitis	PROPN
bionys-568	5	10	b	b	PROPN
bionys-568	5	11	with	with	ADP
bionys-568	5	12	hcc	hcc	PROPN
bionys-568	5	13	,	,	PUNCT
bionys-568	5	14	hcc	hcc	PROPN
bionys-568	5	15	,	,	PUNCT
bionys-568	5	16	and	and	CCONJ
bionys-568	5	17	healthy	healthy	ADJ
bionys-568	5	18	people	people	NOUN
bionys-568	5	19	.	.	PUNCT
bionys-568	6	1	the	the	DET
bionys-568	6	2	samples	sample	NOUN
bionys-568	6	3	were	be	AUX
bionys-568	6	4	genotyped	genotype	VERB
bionys-568	6	5	for	for	ADP
bionys-568	6	6	11β	11β	NUM
bionys-568	6	7	hsd1	hsd1	PROPN
bionys-568	6	8	(	(	PUNCT
bionys-568	6	9	rs846910	rs846910	NOUN
bionys-568	6	10	and	and	CCONJ
bionys-568	6	11	rs12086634	rs12086634	PROPN
bionys-568	6	12	)	)	PUNCT
bionys-568	6	13	using	use	VERB
bionys-568	6	14	allele	allele	NOUN
bionys-568	6	15	-	-	PUNCT
bionys-568	6	16	specific	specific	ADJ
bionys-568	6	17	real	real	ADJ
bionys-568	6	18	-	-	PUNCT
bionys-568	6	19	time	time	NOUN
bionys-568	6	20	pcr	pcr	NOUN
bionys-568	6	21	.	.	PUNCT
bionys-568	7	1	after	after	ADP
bionys-568	7	2	performing	perform	VERB
bionys-568	7	3	genotyping	genotyping	NOUN
bionys-568	7	4	of	of	ADP
bionys-568	7	5	the	the	DET
bionys-568	7	6	11β	11β	NOUN
bionys-568	7	7	-	-	PUNCT
bionys-568	7	8	hsd1	hsd1	ADJ
bionys-568	7	9	gene	gene	NOUN
bionys-568	7	10	using	use	VERB
bionys-568	7	11	real	real	ADJ
bionys-568	7	12	-	-	PUNCT
bionys-568	7	13	time	time	NOUN
bionys-568	7	14	pcr	pcr	NOUN
bionys-568	7	15	,	,	PUNCT
bionys-568	7	16	both	both	PRON
bionys-568	7	17	alleles	allele	VERB
bionys-568	7	18	g	g	NOUN
bionys-568	7	19	and	and	CCONJ
bionys-568	7	20	a	a	PRON
bionys-568	7	21	of	of	ADP
bionys-568	7	22	rs846910	rs846910	NOUN
bionys-568	7	23	were	be	AUX
bionys-568	7	24	found	find	VERB
bionys-568	7	25	to	to	PART
bionys-568	7	26	be	be	AUX
bionys-568	7	27	more	more	ADV
bionys-568	7	28	prevalent	prevalent	ADJ
bionys-568	7	29	in	in	ADP
bionys-568	7	30	the	the	DET
bionys-568	7	31	two	two	NUM
bionys-568	7	32	groups	group	NOUN
bionys-568	7	33	of	of	ADP
bionys-568	7	34	hepatocellular	hepatocellular	ADJ
bionys-568	7	35	carcinoma	carcinoma	NOUN
bionys-568	7	36	and	and	CCONJ
bionys-568	7	37	hepatitis	hepatitis	PROPN
bionys-568	7	38	b.	b.	PROPN
bionys-568	8	1	this	this	PRON
bionys-568	8	2	gives	give	VERB
bionys-568	8	3	a	a	DET
bionys-568	8	4	clear	clear	ADJ
bionys-568	8	5	indication	indication	NOUN
bionys-568	8	6	about	about	ADP
bionys-568	8	7	the	the	DET
bionys-568	8	8	possibility	possibility	NOUN
bionys-568	8	9	of	of	ADP
bionys-568	8	10	contracting	contract	VERB
bionys-568	8	11	hepatocellular	hepatocellular	ADJ
bionys-568	8	12	carcinoma	carcinoma	NOUN
bionys-568	8	13	and	and	CCONJ
bionys-568	8	14	hepatitis	hepatitis	PROPN
bionys-568	8	15	b.	b.	PROPN
bionys-568	9	1	a	a	DET
bionys-568	9	2	different	different	ADJ
bionys-568	9	3	result	result	NOUN
bionys-568	9	4	was	be	AUX
bionys-568	9	5	found	find	VERB
bionys-568	9	6	than	than	ADP
bionys-568	9	7	previously	previously	ADV
bionys-568	9	8	,	,	PUNCT
bionys-568	9	9	as	as	SCONJ
bionys-568	9	10	the	the	DET
bionys-568	9	11	tt	tt	PROPN
bionys-568	9	12	genotype	genotype	NOUN
bionys-568	9	13	of	of	ADP
bionys-568	9	14	rs12086634	rs12086634	PROPN
bionys-568	9	15	showed	show	VERB
bionys-568	9	16	a	a	DET
bionys-568	9	17	protective	protective	ADJ
bionys-568	9	18	effect	effect	NOUN
bionys-568	9	19	against	against	ADP
bionys-568	9	20	hepatocellular	hepatocellular	ADJ
bionys-568	9	21	carcinoma	carcinoma	NOUN
bionys-568	9	22	and	and	CCONJ
bionys-568	9	23	hepatitis	hepatitis	PROPN
bionys-568	9	24	b	b	PROPN
bionys-568	9	25	virus	virus	NOUN
bionys-568	9	26	infection	infection	NOUN
bionys-568	9	27	,	,	PUNCT
bionys-568	9	28	while	while	SCONJ
bionys-568	9	29	the	the	DET
bionys-568	9	30	ag	ag	PROPN
bionys-568	9	31	genotype	genotype	NOUN
bionys-568	9	32	of	of	ADP
bionys-568	9	33	rs846910	rs846910	NOUN
bionys-568	9	34	increased	increase	VERB
bionys-568	9	35	the	the	DET
bionys-568	9	36	risk	risk	NOUN
bionys-568	9	37	of	of	ADP
bionys-568	9	38	hepatocellular	hepatocellular	ADJ
bionys-568	9	39	carcinoma	carcinoma	NOUN
bionys-568	9	40	.	.	PUNCT
bionys-568	10	1	these	these	DET
bionys-568	10	2	genetic	genetic	ADJ
bionys-568	10	3	variations	variation	NOUN
bionys-568	10	4	are	be	AUX
bionys-568	10	5	clearly	clearly	ADV
bionys-568	10	6	significant	significant	ADJ
bionys-568	10	7	biomarkers	biomarker	NOUN
bionys-568	10	8	for	for	ADP
bionys-568	10	9	hepatocellular	hepatocellular	ADJ
bionys-568	10	10	carcinoma	carcinoma	NOUN
bionys-568	10	11	.	.	PUNCT
bionys-568	11	1	key	key	ADJ
bionys-568	11	2	words	word	NOUN
bionys-568	11	3	:	:	PUNCT
bionys-568	11	4	single	single	ADJ
bionys-568	11	5	nucleotide	nucleotide	ADJ
bionys-568	11	6	polymorphism	polymorphism	NOUN
bionys-568	11	7	,	,	PUNCT
bionys-568	11	8	11β	11β	NOUN
bionys-568	11	9	hsd1	hsd1	PROPN
bionys-568	11	10	,	,	PUNCT
bionys-568	11	11	hepatocellular	hepatocellular	ADJ
bionys-568	11	12	carcinoma	carcinoma	NOUN
bionys-568	11	13	(	(	PUNCT
bionys-568	11	14	hcc	hcc	PROPN
bionys-568	11	15	)	)	PUNCT
bionys-568	11	16	apstrakt	apstrakt	NOUN
bionys-568	11	17	:	:	PUNCT
bionys-568	11	18	uloga	uloga	NOUN
bionys-568	11	19	polimorfizama	polimorfizama	NOUN
bionys-568	11	20	gena	gena	PROPN
bionys-568	11	21	11β	11β	PROPN
bionys-568	11	22	-	-	PUNCT
bionys-568	11	23	hidroksisteroid	hidroksisteroid	VERB
bionys-568	11	24	dehidrogenaze	dehidrogenaze	NOUN
bionys-568	11	25	rs846910	rs846910	NOUN
bionys-568	12	1	i	i	PRON
bionys-568	12	2	rs12086634	rs12086634	ADJ
bionys-568	12	3	u	u	NOUN
bionys-568	12	4	etiologiji	etiologiji	PROPN
bionys-568	12	5	hepatocelularnog	hepatocelularnog	NOUN
bionys-568	12	6	carcinoma	carcinoma	NOUN
bionys-568	12	7	u	u	NOUN
bionys-568	12	8	aziji	aziji	PROPN
bionys-568	12	9	,	,	PUNCT
bionys-568	12	10	najčešći	najčešći	PROPN
bionys-568	12	11	uzročnik	uzročnik	X
bionys-568	12	12	hepatocelularnog	hepatocelularnog	PROPN
bionys-568	12	13	karcinoma	karcinoma	PROPN
bionys-568	12	14	(	(	PUNCT
bionys-568	12	15	hcc	hcc	PROPN
bionys-568	12	16	)	)	PUNCT
bionys-568	12	17	je	je	PROPN
bionys-568	12	18	hronični	hronični	PROPN
bionys-568	12	19	hepatitis	hepatitis	PROPN
bionys-568	12	20	b.	b.	PROPN
bionys-568	12	21	genomska	genomska	PROPN
bionys-568	12	22	integracija	integracija	VERB
bionys-568	12	23	hepatitis	hepatitis	PROPN
bionys-568	12	24	b	b	PROPN
bionys-568	12	25	virusa	virusa	NOUN
bionys-568	12	26	(	(	PUNCT
bionys-568	12	27	hbv	hbv	NOUN
bionys-568	12	28	)	)	PUNCT
bionys-568	12	29	je	je	PROPN
bionys-568	12	30	verovatno	verovatno	PROPN
bionys-568	12	31	prekursor	prekursor	NOUN
bionys-568	12	32	karcinogeneze	karcinogeneze	PROPN
bionys-568	12	33	.	.	PUNCT
bionys-568	13	1	integrisani	integrisani	PROPN
bionys-568	13	2	hbv	hbv	PROPN
bionys-568	13	3	genom	genom	PROPN
bionys-568	13	4	može	može	PROPN
bionys-568	13	5	direktno	direktno	PROPN
bionys-568	13	6	aktivirati	aktivirati	PROPN
bionys-568	13	7	obližnje	obližnje	PROPN
bionys-568	13	8	ćelijske	ćelijske	PROPN
bionys-568	13	9	gene	gene	NOUN
bionys-568	13	10	,	,	PUNCT
bionys-568	13	11	omogućavajući	omogućavajući	VERB
bionys-568	13	12	ćelijama	ćelijama	NOUN
bionys-568	13	13	jetre	jetre	NOUN
bionys-568	13	14	selektivnu	selektivnu	PROPN
bionys-568	13	15	prednost	prednost	VERB
bionys-568	13	16	u	u	NOUN
bionys-568	13	17	rastu	rastu	PROPN
bionys-568	13	18	.	.	PUNCT
bionys-568	14	1	cilj	cilj	PROPN
bionys-568	14	2	naše	naše	PROPN
bionys-568	14	3	studije	studije	PROPN
bionys-568	14	4	bio	bio	PROPN
bionys-568	14	5	je	je	PROPN
bionys-568	14	6	da	da	PROPN
bionys-568	14	7	ispita	ispita	PROPN
bionys-568	14	8	da	da	PROPN
bionys-568	14	9	li	li	PROPN
bionys-568	14	10	genetske	genetske	PROPN
bionys-568	14	11	varijante	varijante	PROPN
bionys-568	14	12	u	u	PROPN
bionys-568	14	13	11β	11β	PROPN
bionys-568	14	14	-	-	PUNCT
bionys-568	14	15	hsd1	hsd1	PROPN
bionys-568	14	16	,	,	PUNCT
bionys-568	14	17	rs846910	rs846910	NOUN
bionys-568	14	18	i	i	PRON
bionys-568	14	19	rs12086634	rs12086634	PROPN
bionys-568	14	20	mogu	mogu	PROPN
bionys-568	14	21	biti	biti	PROPN
bionys-568	14	22	povezane	povezane	PROPN
bionys-568	14	23	sa	sa	PROPN
bionys-568	14	24	hroničnom	hroničnom	PROPN
bionys-568	14	25	infekcijom	infekcijom	VERB
bionys-568	14	26	hepatitis	hepatitis	PROPN
bionys-568	14	27	b	b	PROPN
bionys-568	14	28	virusa	virusa	NOUN
bionys-568	14	29	(	(	PUNCT
bionys-568	14	30	hbv	hbv	NOUN
bionys-568	14	31	)	)	PUNCT
bionys-568	15	1	i	i	PRON
bionys-568	15	2	hepatocelularnim	hepatocelularnim	PROPN
bionys-568	15	3	karcinomom	karcinomom	PROPN
bionys-568	15	4	(	(	PUNCT
bionys-568	15	5	hcc	hcc	PROPN
bionys-568	15	6	)	)	PUNCT
bionys-568	15	7	.	.	PUNCT
bionys-568	16	1	ispitano	ispitano	PROPN
bionys-568	16	2	je	je	PROPN
bionys-568	16	3	150	150	NUM
bionys-568	16	4	uzoraka	uzoraka	NOUN
bionys-568	16	5	sakupljenih	sakupljenih	PROPN
bionys-568	16	6	od	od	PROPN
bionys-568	17	1	osoba	osoba	PROPN
bionys-568	17	2	sa	sa	PROPN
bionys-568	17	3	hepatitisom	hepatitisom	PROPN
bionys-568	17	4	b	b	PROPN
bionys-568	18	1	i	i	PRON
bionys-568	18	2	hcc	hcc	PROPN
bionys-568	18	3	,	,	PUNCT
bionys-568	18	4	osoba	osoba	PROPN
bionys-568	18	5	sa	sa	PROPN
bionys-568	18	6	hcc	hcc	PROPN
bionys-568	18	7	,	,	PUNCT
bionys-568	18	8	kao	kao	PROPN
bionys-568	19	1	i	i	PRON
bionys-568	19	2	zdravih	zdravih	NOUN
bionys-568	19	3	ispitanika	ispitanika	X
bionys-568	19	4	.	.	PUNCT
bionys-568	20	1	genotipizacija	genotipizacija	PROPN
bionys-568	20	2	uzoraka	uzoraka	NOUN
bionys-568	20	3	na	na	ADP
bionys-568	20	4	11β	11β	NOUN
bionys-568	20	5	-	-	PUNCT
bionys-568	20	6	hsd1	hsd1	PROPN
bionys-568	20	7	(	(	PUNCT
bionys-568	20	8	rs846910	rs846910	NOUN
bionys-568	20	9	i	i	PRON
bionys-568	20	10	rs12086634	rs12086634	PROPN
bionys-568	20	11	)	)	PUNCT
bionys-568	21	1	izvršena	izvršena	PROPN
bionys-568	21	2	je	je	PROPN
bionys-568	21	3	uz	uz	PROPN
bionys-568	21	4	pomoć	pomoć	PROPN
bionys-568	21	5	alel	alel	ADJ
bionys-568	21	6	-	-	PUNCT
bionys-568	21	7	specifične	specifične	VERB
bionys-568	21	8	real	real	ADJ
bionys-568	21	9	-	-	PUNCT
bionys-568	21	10	time	time	NOUN
bionys-568	21	11	pcr	pcr	PROPN
bionys-568	21	12	metode	metode	PROPN
bionys-568	21	13	.	.	PUNCT
bionys-568	22	1	nakon	nakon	PROPN
bionys-568	22	2	genotipizacije	genotipizacije	PROPN
bionys-568	22	3	11β	11β	PROPN
bionys-568	22	4	-	-	PUNCT
bionys-568	22	5	hsd1	hsd1	PROPN
bionys-568	22	6	gena	gena	PROPN
bionys-568	22	7	uz	uz	PROPN
bionys-568	22	8	pomoć	pomoć	PROPN
bionys-568	22	9	real	real	ADJ
bionys-568	22	10	-	-	PUNCT
bionys-568	22	11	time	time	NOUN
bionys-568	22	12	pcr	pcr	PROPN
bionys-568	22	13	metode	metode	PROPN
bionys-568	22	14	,	,	PUNCT
bionys-568	22	15	utvrđeno	utvrđeno	PROPN
bionys-568	22	16	je	je	PROPN
bionys-568	22	17	da	da	PROPN
bionys-568	22	18	su	su	PROPN
bionys-568	22	19	oba	oba	PROPN
bionys-568	22	20	alela	alela	PROPN
bionys-568	22	21	,	,	PUNCT
bionys-568	22	22	g	g	PROPN
bionys-568	22	23	i	i	PRON
bionys-568	22	24	a	a	X
bionys-568	22	25	,	,	PUNCT
bionys-568	22	26	polimorfizma	polimorfizma	NOUN
bionys-568	22	27	rs846910	rs846910	NOUN
bionys-568	22	28	zastupljenija	zastupljenija	NOUN
bionys-568	22	29	u	u	PROPN
bionys-568	22	30	grupama	grupama	NOUN
bionys-568	22	31	pacijenata	pacijenata	VERB
bionys-568	22	32	sa	sa	ADP
bionys-568	22	33	hepatocelularnim	hepatocelularnim	PROPN
bionys-568	22	34	karcinomom	karcinomom	PROPN
bionys-568	23	1	i	i	PRON
bionys-568	23	2	hepatitisom	hepatitisom	VERB
bionys-568	23	3	b	b	NUM
bionys-568	23	4	,	,	PUNCT
bionys-568	23	5	što	što	PROPN
bionys-568	23	6	ukazuje	ukazuje	NOUN
bionys-568	23	7	na	na	ADP
bionys-568	23	8	povećan	povećan	PROPN
bionys-568	23	9	rizik	rizik	NOUN
bionys-568	23	10	od	od	PROPN
bionys-568	23	11	obolevanja	obolevanja	PROPN
bionys-568	23	12	od	od	PROPN
bionys-568	23	13	ovih	ovih	PROPN
bionys-568	23	14	bolesti	bolesti	PROPN
bionys-568	23	15	.	.	PUNCT
bionys-568	24	1	nasuprot	nasuprot	VERB
bionys-568	24	2	ranijim	ranijim	ADJ
bionys-568	24	3	rezultatima	rezultatima	PROPN
bionys-568	24	4	,	,	PUNCT
bionys-568	24	5	genotip	genotip	VERB
bionys-568	24	6	tt	tt	PROPN
bionys-568	24	7	polimorfizma	polimorfizma	PROPN
bionys-568	24	8	rs12086634	rs12086634	PROPN
bionys-568	24	9	pokazao	pokazao	PROPN
bionys-568	24	10	je	je	PROPN
bionys-568	24	11	zaštitni	zaštitni	PROPN
bionys-568	24	12	efekat	efekat	VERB
bionys-568	24	13	protiv	protiv	PROPN
bionys-568	24	14	hepatocelularnog	hepatocelularnog	PROPN
bionys-568	24	15	karcinoma	karcinoma	NOUN
bionys-568	25	1	i	i	PRON
bionys-568	25	2	infekcija	infekcija	VERB
bionys-568	25	3	izazvanih	izazvanih	VERB
bionys-568	25	4	hepatitis	hepatitis	PROPN
bionys-568	25	5	b	b	PROPN
bionys-568	25	6	virusom	virusom	PROPN
bionys-568	25	7	,	,	PUNCT
bionys-568	25	8	dok	dok	PROPN
bionys-568	25	9	je	je	PROPN
bionys-568	25	10	ag	ag	PROPN
bionys-568	25	11	genotip	genotip	PROPN
bionys-568	25	12	rs846910	rs846910	NOUN
bionys-568	25	13	bio	bio	PROPN
bionys-568	25	14	povezan	povezan	PROPN
bionys-568	25	15	sa	sa	PROPN
bionys-568	25	16	povećanim	povećanim	PROPN
bionys-568	25	17	rizikom	rizikom	PROPN
bionys-568	25	18	od	od	PROPN
bionys-568	25	19	hepatocelularnog	hepatocelularnog	PROPN
bionys-568	25	20	karcinoma	karcinoma	PROPN
bionys-568	25	21	.	.	PUNCT
bionys-568	26	1	ove	ove	PROPN
bionys-568	26	2	genetske	genetske	PROPN
bionys-568	26	3	varijacije	varijacije	PROPN
bionys-568	26	4	predstavljaju	predstavljaju	PROPN
bionys-568	26	5	značajne	značajne	PROPN
bionys-568	26	6	biomarkere	biomarkere	PROPN
bionys-568	26	7	za	za	PROPN
bionys-568	26	8	hepatocelularni	hepatocelularni	PROPN
bionys-568	26	9	karcinom	karcinom	PROPN
bionys-568	26	10	.	.	PUNCT
bionys-568	27	1	ključne	ključne	PROPN
bionys-568	27	2	reči	reči	NOUN
bionys-568	27	3	:	:	PUNCT
bionys-568	27	4	jednonukleotidni	jednonukleotidni	PROPN
bionys-568	27	5	polimorfizam	polimorfizam	PROPN
bionys-568	27	6	(	(	PUNCT
bionys-568	27	7	snp	snp	ADJ
bionys-568	27	8	)	)	PUNCT
bionys-568	27	9	,	,	PUNCT
bionys-568	27	10	11β	11β	NOUN
bionys-568	27	11	hsd1	hsd1	PROPN
bionys-568	27	12	,	,	PUNCT
bionys-568	27	13	hepatocelularni	hepatocelularni	ADJ
bionys-568	27	14	karcinom	karcinom	PROPN
bionys-568	27	15	(	(	PUNCT
bionys-568	27	16	hcc	hcc	PROPN
bionys-568	27	17	)	)	PUNCT
bionys-568	28	1	©	©	PROPN
bionys-568	28	2	2025	2025	NUM
bionys-568	28	3	al	al	PROPN
bionys-568	28	4	-	-	PUNCT
bionys-568	28	5	khaykanee	khaykanee	PROPN
bionys-568	28	6	et	et	PROPN
bionys-568	28	7	al	al	PROPN
bionys-568	28	8	.	.	PUNCT
bionys-568	29	1	this	this	PRON
bionys-568	29	2	is	be	AUX
bionys-568	29	3	an	an	DET
bionys-568	29	4	open	open	ADJ
bionys-568	29	5	-	-	PUNCT
bionys-568	29	6	access	access	NOUN
bionys-568	29	7	article	article	NOUN
bionys-568	29	8	distributed	distribute	VERB
bionys-568	29	9	under	under	ADP
bionys-568	29	10	the	the	DET
bionys-568	29	11	terms	term	NOUN
bionys-568	29	12	of	of	ADP
bionys-568	29	13	the	the	DET
bionys-568	29	14	creative	creative	ADJ
bionys-568	29	15	commons	common	NOUN
bionys-568	29	16	attribution	attribution	NOUN
bionys-568	29	17	license	license	NOUN
bionys-568	29	18	,	,	PUNCT
bionys-568	29	19	which	which	PRON
bionys-568	29	20	permits	permit	VERB
bionys-568	29	21	unrestricted	unrestricted	ADJ
bionys-568	29	22	use	use	NOUN
bionys-568	29	23	,	,	PUNCT
bionys-568	29	24	distribution	distribution	NOUN
bionys-568	29	25	,	,	PUNCT
bionys-568	29	26	and	and	CCONJ
bionys-568	29	27	build	build	VERB
bionys-568	29	28	upon	upon	SCONJ
bionys-568	29	29	your	your	PRON
bionys-568	29	30	work	work	NOUN
bionys-568	29	31	non	non	ADJ
bionys-568	29	32	-	-	ADJ
bionys-568	29	33	commercially	commercially	ADV
bionys-568	29	34	under	under	ADP
bionys-568	29	35	the	the	DET
bionys-568	29	36	same	same	ADJ
bionys-568	29	37	license	license	NOUN
bionys-568	29	38	as	as	ADP
bionys-568	29	39	the	the	DET
bionys-568	29	40	original	original	ADJ
bionys-568	29	41	.	.	PUNCT
bionys-568	30	1	288	288	NUM
bionys-568	30	2	introduction	introduction	NOUN
bionys-568	30	3	liver	liver	NOUN
bionys-568	30	4	cancer	cancer	NOUN
bionys-568	30	5	ranks	rank	VERB
bionys-568	30	6	sixth	sixth	ADJ
bionys-568	30	7	in	in	ADP
bionys-568	30	8	terms	term	NOUN
bionys-568	30	9	of	of	ADP
bionys-568	30	10	prevalence	prevalence	NOUN
bionys-568	30	11	and	and	CCONJ
bionys-568	30	12	number	number	NOUN
bionys-568	30	13	of	of	ADP
bionys-568	30	14	cases	case	NOUN
bionys-568	30	15	in	in	ADP
bionys-568	30	16	the	the	DET
bionys-568	30	17	world	world	NOUN
bionys-568	30	18	,	,	PUNCT
bionys-568	30	19	and	and	CCONJ
bionys-568	30	20	fourth	fourth	ADJ
bionys-568	30	21	in	in	ADP
bionys-568	30	22	terms	term	NOUN
bionys-568	30	23	of	of	ADP
bionys-568	30	24	the	the	DET
bionys-568	30	25	number	number	NOUN
bionys-568	30	26	of	of	ADP
bionys-568	30	27	deaths	death	NOUN
bionys-568	30	28	resulting	result	VERB
bionys-568	30	29	from	from	ADP
bionys-568	30	30	it	it	PRON
bionys-568	30	31	.	.	PUNCT
bionys-568	31	1	it	it	PRON
bionys-568	31	2	is	be	AUX
bionys-568	31	3	a	a	DET
bionys-568	31	4	global	global	ADJ
bionys-568	31	5	health	health	NOUN
bionys-568	31	6	problem	problem	NOUN
bionys-568	31	7	and	and	CCONJ
bionys-568	31	8	one	one	NUM
bionys-568	31	9	of	of	ADP
bionys-568	31	10	its	its	PRON
bionys-568	31	11	causes	cause	NOUN
bionys-568	31	12	is	be	AUX
bionys-568	31	13	nonalcoholic	nonalcoholic	ADJ
bionys-568	31	14	fatty	fatty	NOUN
bionys-568	31	15	liver	liver	NOUN
bionys-568	31	16	disease	disease	NOUN
bionys-568	31	17	,	,	PUNCT
bionys-568	31	18	a	a	DET
bionys-568	31	19	risk	risk	NOUN
bionys-568	31	20	factor	factor	NOUN
bionys-568	31	21	for	for	ADP
bionys-568	31	22	this	this	DET
bionys-568	31	23	type	type	NOUN
bionys-568	31	24	of	of	ADP
bionys-568	31	25	cancer	cancer	NOUN
bionys-568	31	26	(	(	PUNCT
bionys-568	31	27	brown	brown	PROPN
bionys-568	31	28	et	et	PROPN
bionys-568	31	29	al	al	PROPN
bionys-568	31	30	.	.	PROPN
bionys-568	31	31	,	,	PUNCT
bionys-568	31	32	2023	2023	NUM
bionys-568	31	33	)	)	PUNCT
bionys-568	31	34	.	.	PUNCT
bionys-568	32	1	hepatocellular	hepatocellular	ADJ
bionys-568	32	2	carcinoma	carcinoma	NOUN
bionys-568	32	3	is	be	AUX
bionys-568	32	4	currently	currently	ADV
bionys-568	32	5	the	the	DET
bionys-568	32	6	most	most	ADV
bionys-568	32	7	common	common	ADJ
bionys-568	32	8	in	in	ADP
bionys-568	32	9	north	north	PROPN
bionys-568	32	10	africa	africa	PROPN
bionys-568	32	11	,	,	PUNCT
bionys-568	32	12	southeast	southeast	PROPN
bionys-568	32	13	asia	asia	PROPN
bionys-568	32	14	,	,	PUNCT
bionys-568	32	15	and	and	CCONJ
bionys-568	32	16	east	east	PROPN
bionys-568	32	17	asia	asia	PROPN
bionys-568	32	18	(	(	PUNCT
bionys-568	32	19	rumgay	rumgay	NOUN
bionys-568	32	20	et	et	PROPN
bionys-568	32	21	al	al	PROPN
bionys-568	32	22	.	.	PROPN
bionys-568	32	23	,	,	PUNCT
bionys-568	32	24	2022	2022	NUM
bionys-568	32	25	)	)	PUNCT
bionys-568	32	26	.	.	PUNCT
bionys-568	33	1	the	the	DET
bionys-568	33	2	risk	risk	NOUN
bionys-568	33	3	of	of	ADP
bionys-568	33	4	developing	develop	VERB
bionys-568	33	5	hepatocellular	hepatocellular	ADJ
bionys-568	33	6	carcinoma	carcinoma	NOUN
bionys-568	33	7	increases	increase	NOUN
bionys-568	33	8	when	when	SCONJ
bionys-568	33	9	there	there	PRON
bionys-568	33	10	is	be	VERB
bionys-568	33	11	cirrhosis	cirrhosis	NOUN
bionys-568	33	12	of	of	ADP
bionys-568	33	13	the	the	DET
bionys-568	33	14	liver	liver	NOUN
bionys-568	33	15	,	,	PUNCT
bionys-568	33	16	and	and	CCONJ
bionys-568	33	17	it	it	PRON
bionys-568	33	18	rarely	rarely	ADV
bionys-568	33	19	occurs	occur	VERB
bionys-568	33	20	in	in	ADP
bionys-568	33	21	a	a	DET
bionys-568	33	22	healthy	healthy	ADJ
bionys-568	33	23	liver	liver	NOUN
bionys-568	33	24	.	.	PUNCT
bionys-568	34	1	one	one	NUM
bionys-568	34	2	of	of	ADP
bionys-568	34	3	the	the	DET
bionys-568	34	4	main	main	ADJ
bionys-568	34	5	causes	cause	NOUN
bionys-568	34	6	of	of	ADP
bionys-568	34	7	infection	infection	NOUN
bionys-568	34	8	is	be	AUX
bionys-568	34	9	the	the	DET
bionys-568	34	10	hepatitis	hepatitis	PROPN
bionys-568	34	11	b	b	PROPN
bionys-568	34	12	virus	virus	PROPN
bionys-568	34	13	,	,	PUNCT
bionys-568	34	14	which	which	PRON
bionys-568	34	15	is	be	AUX
bionys-568	34	16	responsible	responsible	ADJ
bionys-568	34	17	for	for	ADP
bionys-568	34	18	about	about	ADV
bionys-568	34	19	50	50	NUM
bionys-568	34	20	%	%	NOUN
bionys-568	34	21	of	of	ADP
bionys-568	34	22	cases	case	NOUN
bionys-568	34	23	of	of	ADP
bionys-568	34	24	this	this	DET
bionys-568	34	25	type	type	NOUN
bionys-568	34	26	of	of	ADP
bionys-568	34	27	cancer	cancer	NOUN
bionys-568	34	28	(	(	PUNCT
bionys-568	34	29	akinyemiju	akinyemiju	PROPN
bionys-568	34	30	et	et	PROPN
bionys-568	34	31	al	al	PROPN
bionys-568	34	32	.	.	PROPN
bionys-568	34	33	,	,	PUNCT
bionys-568	34	34	2017	2017	NUM
bionys-568	34	35	)	)	PUNCT
bionys-568	34	36	.	.	PUNCT
bionys-568	35	1	the	the	DET
bionys-568	35	2	5	5	NUM
bionys-568	35	3	-	-	PUNCT
bionys-568	35	4	year	year	NOUN
bionys-568	35	5	survival	survival	NOUN
bionys-568	35	6	rate	rate	NOUN
bionys-568	35	7	for	for	ADP
bionys-568	35	8	hepatocellular	hepatocellular	ADJ
bionys-568	35	9	carcinoma	carcinoma	NOUN
bionys-568	35	10	is	be	AUX
bionys-568	35	11	approximately	approximately	ADV
bionys-568	35	12	18.4	18.4	NUM
bionys-568	35	13	%	%	NOUN
bionys-568	35	14	(	(	PUNCT
bionys-568	35	15	leowattana	leowattana	PROPN
bionys-568	35	16	et	et	PROPN
bionys-568	35	17	al	al	PROPN
bionys-568	35	18	.	.	PROPN
bionys-568	35	19	,	,	PUNCT
bionys-568	35	20	2023	2023	NUM
bionys-568	35	21	)	)	PUNCT
bionys-568	35	22	.	.	PUNCT
bionys-568	36	1	hepatitis	hepatitis	PROPN
bionys-568	36	2	b	b	PROPN
bionys-568	36	3	virus	virus	NOUN
bionys-568	36	4	(	(	PUNCT
bionys-568	36	5	hbv	hbv	NOUN
bionys-568	36	6	)	)	PUNCT
bionys-568	36	7	is	be	AUX
bionys-568	36	8	a	a	DET
bionys-568	36	9	member	member	NOUN
bionys-568	36	10	of	of	ADP
bionys-568	36	11	the	the	DET
bionys-568	36	12	hepadnaviridae	hepadnaviridae	NOUN
bionys-568	36	13	family	family	NOUN
bionys-568	36	14	and	and	CCONJ
bionys-568	36	15	consists	consist	VERB
bionys-568	36	16	of	of	ADP
bionys-568	36	17	only	only	ADV
bionys-568	36	18	3,200	3,200	NUM
bionys-568	36	19	nucleotides	nucleotide	NOUN
bionys-568	36	20	and	and	CCONJ
bionys-568	36	21	is	be	AUX
bionys-568	36	22	the	the	DET
bionys-568	36	23	smallest	small	ADJ
bionys-568	36	24	virus	virus	NOUN
bionys-568	36	25	that	that	PRON
bionys-568	36	26	infects	infect	VERB
bionys-568	36	27	humans	human	NOUN
bionys-568	36	28	.	.	PUNCT
bionys-568	37	1	the	the	DET
bionys-568	37	2	absence	absence	NOUN
bionys-568	37	3	of	of	ADP
bionys-568	37	4	a	a	DET
bionys-568	37	5	proofreading	proofreading	NOUN
bionys-568	37	6	mechanism	mechanism	NOUN
bionys-568	37	7	in	in	ADP
bionys-568	37	8	hbv	hbv	NOUN
bionys-568	37	9	reverse	reverse	NOUN
bionys-568	37	10	transcriptase	transcriptase	NOUN
bionys-568	37	11	facilitates	facilitate	VERB
bionys-568	37	12	the	the	DET
bionys-568	37	13	emergence	emergence	NOUN
bionys-568	37	14	of	of	ADP
bionys-568	37	15	a	a	DET
bionys-568	37	16	varied	varied	ADJ
bionys-568	37	17	range	range	NOUN
bionys-568	37	18	of	of	ADP
bionys-568	37	19	genomic	genomic	ADJ
bionys-568	37	20	variants	variant	NOUN
bionys-568	37	21	throughout	throughout	ADP
bionys-568	37	22	different	different	ADJ
bionys-568	37	23	stages	stage	NOUN
bionys-568	37	24	of	of	ADP
bionys-568	37	25	infection	infection	NOUN
bionys-568	37	26	.	.	PUNCT
bionys-568	38	1	analysis	analysis	NOUN
bionys-568	38	2	of	of	ADP
bionys-568	38	3	hbv	hbv	NOUN
bionys-568	38	4	genomic	genomic	NOUN
bionys-568	38	5	sequence	sequence	NOUN
bionys-568	38	6	divergence	divergence	NOUN
bionys-568	38	7	has	have	AUX
bionys-568	38	8	identified	identify	VERB
bionys-568	38	9	several	several	ADJ
bionys-568	38	10	sub	sub	NOUN
bionys-568	38	11	genotypes	genotype	NOUN
bionys-568	38	12	and	and	CCONJ
bionys-568	38	13	ten	ten	NUM
bionys-568	38	14	hbv	hbv	NOUN
bionys-568	38	15	genotypes	genotype	NOUN
bionys-568	38	16	(	(	PUNCT
bionys-568	38	17	trépo	trépo	NOUN
bionys-568	38	18	et	et	NOUN
bionys-568	38	19	al	al	PROPN
bionys-568	38	20	.	.	PROPN
bionys-568	38	21	,	,	PUNCT
bionys-568	38	22	2014	2014	NUM
bionys-568	38	23	;	;	PUNCT
bionys-568	38	24	razavi	razavi	PROPN
bionys-568	38	25	-	-	PUNCT
bionys-568	38	26	shearer	shearer	PROPN
bionys-568	38	27	et	et	PROPN
bionys-568	38	28	al	al	PROPN
bionys-568	38	29	.	.	PROPN
bionys-568	38	30	,	,	PUNCT
bionys-568	38	31	2018	2018	NUM
bionys-568	38	32	)	)	PUNCT
bionys-568	38	33	.	.	PUNCT
bionys-568	39	1	the	the	DET
bionys-568	39	2	lack	lack	NOUN
bionys-568	39	3	of	of	ADP
bionys-568	39	4	a	a	DET
bionys-568	39	5	proofreading	proofreading	NOUN
bionys-568	39	6	mechanism	mechanism	NOUN
bionys-568	39	7	in	in	ADP
bionys-568	39	8	hbv	hbv	NOUN
bionys-568	39	9	reverse	reverse	NOUN
bionys-568	39	10	transcriptase	transcriptase	NOUN
bionys-568	39	11	facilitates	facilitate	VERB
bionys-568	39	12	a	a	DET
bionys-568	39	13	diverse	diverse	ADJ
bionys-568	39	14	array	array	NOUN
bionys-568	39	15	of	of	ADP
bionys-568	39	16	genomic	genomic	ADJ
bionys-568	39	17	variations	variation	NOUN
bionys-568	39	18	for	for	ADP
bionys-568	39	19	selective	selective	ADJ
bionys-568	39	20	proliferation	proliferation	NOUN
bionys-568	39	21	throughout	throughout	ADP
bionys-568	39	22	various	various	ADJ
bionys-568	39	23	stages	stage	NOUN
bionys-568	39	24	of	of	ADP
bionys-568	39	25	infection	infection	NOUN
bionys-568	39	26	.	.	PUNCT
bionys-568	40	1	analysis	analysis	NOUN
bionys-568	40	2	of	of	ADP
bionys-568	40	3	hbv	hbv	NOUN
bionys-568	40	4	genomic	genomic	NOUN
bionys-568	40	5	sequence	sequence	NOUN
bionys-568	40	6	divergence	divergence	NOUN
bionys-568	40	7	has	have	AUX
bionys-568	40	8	identified	identify	VERB
bionys-568	40	9	multiple	multiple	ADJ
bionys-568	40	10	sub	sub	NOUN
bionys-568	40	11	genotypes	genotype	NOUN
bionys-568	40	12	and	and	CCONJ
bionys-568	40	13	eleven	eleven	NUM
bionys-568	40	14	hbv	hbv	NOUN
bionys-568	40	15	genotypes	genotype	NOUN
bionys-568	40	16	(	(	PUNCT
bionys-568	40	17	assefa	assefa	NOUN
bionys-568	40	18	et	et	PROPN
bionys-568	40	19	al	al	PROPN
bionys-568	40	20	.	.	PROPN
bionys-568	40	21	,	,	PUNCT
bionys-568	40	22	2024	2024	NUM
bionys-568	40	23	)	)	PUNCT
bionys-568	40	24	.	.	PUNCT
bionys-568	41	1	hepatitis	hepatitis	PROPN
bionys-568	41	2	b	b	PROPN
bionys-568	41	3	virus	virus	NOUN
bionys-568	41	4	(	(	PUNCT
bionys-568	41	5	hbv	hbv	NOUN
bionys-568	41	6	)	)	PUNCT
bionys-568	41	7	belongs	belong	VERB
bionys-568	41	8	to	to	ADP
bionys-568	41	9	the	the	DET
bionys-568	41	10	hepadnaviridae	hepadnaviridae	NOUN
bionys-568	41	11	family	family	NOUN
bionys-568	41	12	.	.	PUNCT
bionys-568	42	1	it	it	PRON
bionys-568	42	2	is	be	AUX
bionys-568	42	3	an	an	DET
bionys-568	42	4	epidemic	epidemic	NOUN
bionys-568	42	5	liver	liver	NOUN
bionys-568	42	6	disease	disease	NOUN
bionys-568	42	7	.	.	PUNCT
bionys-568	43	1	people	people	NOUN
bionys-568	43	2	who	who	PRON
bionys-568	43	3	carry	carry	VERB
bionys-568	43	4	this	this	DET
bionys-568	43	5	virus	virus	NOUN
bionys-568	43	6	are	be	AUX
bionys-568	43	7	more	more	ADV
bionys-568	43	8	susceptible	susceptible	ADJ
bionys-568	43	9	to	to	ADP
bionys-568	43	10	liver	liver	NOUN
bionys-568	43	11	cancer	cancer	NOUN
bionys-568	43	12	.	.	PUNCT
bionys-568	44	1	it	it	PRON
bionys-568	44	2	has	have	VERB
bionys-568	44	3	the	the	DET
bionys-568	44	4	ability	ability	NOUN
bionys-568	44	5	to	to	PART
bionys-568	44	6	multiply	multiply	VERB
bionys-568	44	7	within	within	ADP
bionys-568	44	8	liver	liver	NOUN
bionys-568	44	9	cells	cell	NOUN
bionys-568	44	10	and	and	CCONJ
bionys-568	44	11	interacts	interact	VERB
bionys-568	44	12	with	with	ADP
bionys-568	44	13	many	many	ADJ
bionys-568	44	14	proteins	protein	NOUN
bionys-568	44	15	.	.	PUNCT
bionys-568	45	1	it	it	PRON
bionys-568	45	2	also	also	ADV
bionys-568	45	3	leads	lead	VERB
bionys-568	45	4	to	to	ADP
bionys-568	45	5	gradual	gradual	ADJ
bionys-568	45	6	liver	liver	NOUN
bionys-568	45	7	fibrosis	fibrosis	NOUN
bionys-568	45	8	and	and	CCONJ
bionys-568	45	9	is	be	AUX
bionys-568	45	10	considered	consider	VERB
bionys-568	45	11	a	a	DET
bionys-568	45	12	risk	risk	NOUN
bionys-568	45	13	factor	factor	NOUN
bionys-568	45	14	for	for	ADP
bionys-568	45	15	hcc	hcc	PROPN
bionys-568	45	16	or	or	CCONJ
bionys-568	45	17	hepatocellular	hepatocellular	ADJ
bionys-568	45	18	carcinoma	carcinoma	NOUN
bionys-568	45	19	,	,	PUNCT
bionys-568	45	20	adversely	adversely	ADV
bionys-568	45	21	affecting	affect	VERB
bionys-568	45	22	the	the	DET
bionys-568	45	23	survival	survival	NOUN
bionys-568	45	24	of	of	ADP
bionys-568	45	25	people	people	NOUN
bionys-568	45	26	with	with	ADP
bionys-568	45	27	hepatitis	hepatitis	PROPN
bionys-568	45	28	b	b	PROPN
bionys-568	45	29	virus	virus	NOUN
bionys-568	45	30	,	,	PUNCT
bionys-568	45	31	while	while	SCONJ
bionys-568	45	32	concomitant	concomitant	ADJ
bionys-568	45	33	hepatitis	hepatitis	PROPN
bionys-568	45	34	d	d	PROPN
bionys-568	45	35	virus	virus	NOUN
bionys-568	45	36	infection	infection	NOUN
bionys-568	45	37	exacerbates	exacerbate	VERB
bionys-568	45	38	the	the	DET
bionys-568	45	39	condition	condition	NOUN
bionys-568	45	40	.	.	PUNCT
bionys-568	46	1	evidence	evidence	NOUN
bionys-568	46	2	indicates	indicate	VERB
bionys-568	46	3	that	that	SCONJ
bionys-568	46	4	hbv	hbv	NOUN
bionys-568	46	5	infection	infection	NOUN
bionys-568	46	6	correlates	correlate	VERB
bionys-568	46	7	with	with	ADP
bionys-568	46	8	the	the	DET
bionys-568	46	9	likelihood	likelihood	NOUN
bionys-568	46	10	of	of	ADP
bionys-568	46	11	developing	develop	VERB
bionys-568	46	12	hcc	hcc	PROPN
bionys-568	46	13	,	,	PUNCT
bionys-568	46	14	irrespective	irrespective	ADV
bionys-568	46	15	of	of	ADP
bionys-568	46	16	the	the	DET
bionys-568	46	17	presence	presence	NOUN
bionys-568	46	18	of	of	ADP
bionys-568	46	19	underlying	underlie	VERB
bionys-568	46	20	liver	liver	NOUN
bionys-568	46	21	cirrhosis	cirrhosis	NOUN
bionys-568	46	22	,	,	PUNCT
bionys-568	46	23	through	through	ADP
bionys-568	46	24	multiple	multiple	ADJ
bionys-568	46	25	direct	direct	ADJ
bionys-568	46	26	and	and	CCONJ
bionys-568	46	27	indirect	indirect	ADJ
bionys-568	46	28	pathways	pathway	NOUN
bionys-568	46	29	that	that	PRON
bionys-568	46	30	facilitate	facilitate	VERB
bionys-568	46	31	hepatocarcinogenesis	hepatocarcinogenesis	NOUN
bionys-568	46	32	(	(	PUNCT
bionys-568	46	33	rizzo	rizzo	PROPN
bionys-568	46	34	et	et	PROPN
bionys-568	46	35	al	al	PROPN
bionys-568	46	36	.	.	PROPN
bionys-568	46	37	,	,	PUNCT
bionys-568	46	38	2022	2022	NUM
bionys-568	46	39	)	)	PUNCT
bionys-568	46	40	.	.	PUNCT
bionys-568	47	1	the	the	DET
bionys-568	47	2	human	human	ADJ
bionys-568	47	3	chromosome	chromosome	NOUN
bionys-568	47	4	1	1	NUM
bionys-568	47	5	has	have	VERB
bionys-568	47	6	the	the	DET
bionys-568	47	7	hsd11b1	hsd11b1	ADJ
bionys-568	47	8	gene	gene	NOUN
bionys-568	47	9	.	.	PUNCT
bionys-568	48	1	in	in	ADP
bionys-568	48	2	humans	human	NOUN
bionys-568	48	3	,	,	PUNCT
bionys-568	48	4	the	the	DET
bionys-568	48	5	gene	gene	NOUN
bionys-568	48	6	located	locate	VERB
bionys-568	48	7	on	on	ADP
bionys-568	48	8	chromosome	chromosome	NOUN
bionys-568	48	9	16	16	NUM
bionys-568	48	10	encodes	encode	NOUN
bionys-568	48	11	11	11	NUM
bionys-568	48	12	-	-	PUNCT
bionys-568	48	13	hsd2	hsd2	NOUN
bionys-568	48	14	.	.	PUNCT
bionys-568	49	1	the	the	DET
bionys-568	49	2	two	two	NUM
bionys-568	49	3	types	type	NOUN
bionys-568	49	4	of	of	ADP
bionys-568	49	5	11	11	NUM
bionys-568	49	6	-	-	PUNCT
bionys-568	49	7	hydroxysteroid	hydroxysteroid	PROPN
bionys-568	49	8	dehydrogenases	dehydrogenase	NOUN
bionys-568	49	9	are	be	AUX
bionys-568	49	10	microsomal	microsomal	ADJ
bionys-568	49	11	enzymes	enzyme	NOUN
bionys-568	49	12	associated	associate	VERB
bionys-568	49	13	with	with	ADP
bionys-568	49	14	the	the	DET
bionys-568	49	15	cellular	cellular	ADJ
bionys-568	49	16	membrane	membrane	NOUN
bionys-568	49	17	of	of	ADP
bionys-568	49	18	the	the	DET
bionys-568	49	19	endoplasmic	endoplasmic	ADJ
bionys-568	49	20	reticulum	reticulum	NOUN
bionys-568	49	21	.	.	PUNCT
bionys-568	50	1	11	11	NUM
bionys-568	50	2	-	-	NUM
bionys-568	50	3	hsd1	hsd1	PROPN
bionys-568	50	4	is	be	AUX
bionys-568	50	5	expressed	express	VERB
bionys-568	50	6	in	in	ADP
bionys-568	50	7	the	the	DET
bionys-568	50	8	brain	brain	NOUN
bionys-568	50	9	,	,	PUNCT
bionys-568	50	10	hepatic	hepatic	ADJ
bionys-568	50	11	adipose	adipose	ADJ
bionys-568	50	12	tissue	tissue	NOUN
bionys-568	50	13	,	,	PUNCT
bionys-568	50	14	and	and	CCONJ
bionys-568	50	15	arteries	artery	NOUN
bionys-568	50	16	.	.	PUNCT
bionys-568	51	1	its	its	PRON
bionys-568	51	2	function	function	NOUN
bionys-568	51	3	is	be	AUX
bionys-568	51	4	to	to	PART
bionys-568	51	5	promote	promote	VERB
bionys-568	51	6	the	the	DET
bionys-568	51	7	enactment	enactment	NOUN
bionys-568	51	8	of	of	ADP
bionys-568	51	9	the	the	DET
bionys-568	51	10	glucocorticoid	glucocorticoid	ADJ
bionys-568	51	11	receptor	receptor	NOUN
bionys-568	51	12	by	by	ADP
bionys-568	51	13	facilitating	facilitate	VERB
bionys-568	51	14	the	the	DET
bionys-568	51	15	centralization	centralization	NOUN
bionys-568	51	16	of	of	ADP
bionys-568	51	17	the	the	DET
bionys-568	51	18	dynamic	dynamic	ADJ
bionys-568	51	19	type	type	NOUN
bionys-568	51	20	of	of	ADP
bionys-568	51	21	glucocorticoids	glucocorticoid	NOUN
bionys-568	51	22	in	in	ADP
bionys-568	51	23	the	the	DET
bionys-568	51	24	tissue	tissue	NOUN
bionys-568	51	25	.	.	PUNCT
bionys-568	52	1	as	as	ADP
bionys-568	52	2	a	a	DET
bionys-568	52	3	result	result	NOUN
bionys-568	52	4	,	,	PUNCT
bionys-568	52	5	11	11	NUM
bionys-568	52	6	-	-	PUNCT
bionys-568	52	7	hsd2	hsd2	NOUN
bionys-568	52	8	is	be	AUX
bionys-568	52	9	present	present	ADJ
bionys-568	52	10	in	in	ADP
bionys-568	52	11	tissues	tissue	NOUN
bionys-568	52	12	connected	connect	VERB
bionys-568	52	13	to	to	ADP
bionys-568	52	14	mineralocorticoid	mineralocorticoid	NOUN
bionys-568	52	15	activity	activity	NOUN
bionys-568	52	16	,	,	PUNCT
bionys-568	52	17	the	the	DET
bionys-568	52	18	kidney	kidney	NOUN
bionys-568	52	19	,	,	PUNCT
bionys-568	52	20	the	the	DET
bionys-568	52	21	placenta	placenta	NOUN
bionys-568	52	22	,	,	PUNCT
bionys-568	52	23	and	and	CCONJ
bionys-568	52	24	the	the	DET
bionys-568	52	25	salivary	salivary	ADJ
bionys-568	52	26	organs	organ	NOUN
bionys-568	52	27	(	(	PUNCT
bionys-568	52	28	studzińska	studzińska	VERB
bionys-568	52	29	et	et	PROPN
bionys-568	52	30	al	al	PROPN
bionys-568	52	31	.	.	PROPN
bionys-568	52	32	,	,	PUNCT
bionys-568	52	33	2018	2018	NUM
bionys-568	52	34	;	;	PUNCT
bionys-568	52	35	de	de	X
bionys-568	52	36	kloet	kloet	VERB
bionys-568	52	37	et	et	PROPN
bionys-568	52	38	al	al	PROPN
bionys-568	52	39	.	.	PROPN
bionys-568	52	40	,	,	PUNCT
bionys-568	52	41	2019	2019	NUM
bionys-568	52	42	)	)	PUNCT
bionys-568	52	43	.	.	PUNCT
bionys-568	53	1	increased	increase	VERB
bionys-568	53	2	cortisol	cortisol	ADJ
bionys-568	53	3	levels	level	NOUN
bionys-568	53	4	are	be	AUX
bionys-568	53	5	observed	observe	VERB
bionys-568	53	6	during	during	ADP
bionys-568	53	7	the	the	DET
bionys-568	53	8	bipolar	bipolar	ADJ
bionys-568	53	9	episode	episode	NOUN
bionys-568	53	10	,	,	PUNCT
bionys-568	53	11	suggesting	suggest	VERB
bionys-568	53	12	activation	activation	NOUN
bionys-568	53	13	of	of	ADP
bionys-568	53	14	the	the	DET
bionys-568	53	15	hpa	hpa	NOUN
bionys-568	53	16	(	(	PUNCT
bionys-568	53	17	watson	watson	PROPN
bionys-568	53	18	et	et	PROPN
bionys-568	53	19	al	al	PROPN
bionys-568	53	20	.	.	PROPN
bionys-568	53	21	,	,	PUNCT
bionys-568	53	22	2012	2012	NUM
bionys-568	53	23	)	)	PUNCT
bionys-568	53	24	.	.	PUNCT
bionys-568	54	1	various	various	ADJ
bionys-568	54	2	analyses	analysis	NOUN
bionys-568	54	3	have	have	AUX
bionys-568	54	4	suggested	suggest	VERB
bionys-568	54	5	that	that	SCONJ
bionys-568	54	6	11β	11β	NOUN
bionys-568	54	7	-	-	PUNCT
bionys-568	54	8	hsd1	hsd1	PROPN
bionys-568	54	9	plays	play	VERB
bionys-568	54	10	a	a	DET
bionys-568	54	11	major	major	ADJ
bionys-568	54	12	and	and	CCONJ
bionys-568	54	13	helpful	helpful	ADJ
bionys-568	54	14	role	role	NOUN
bionys-568	54	15	in	in	ADP
bionys-568	54	16	the	the	DET
bionys-568	54	17	metabolic	metabolic	NOUN
bionys-568	54	18	cycles	cycle	NOUN
bionys-568	54	19	that	that	PRON
bionys-568	54	20	underlie	underlie	VERB
bionys-568	54	21	various	various	ADJ
bionys-568	54	22	diseases	disease	NOUN
bionys-568	54	23	.	.	PUNCT
bionys-568	55	1	in	in	ADP
bionys-568	55	2	animals	animal	NOUN
bionys-568	55	3	lacking	lack	VERB
bionys-568	55	4	11β	11β	NOUN
bionys-568	55	5	-	-	PUNCT
bionys-568	55	6	hsd1	hsd1	PROPN
bionys-568	55	7	,	,	PUNCT
bionys-568	55	8	the	the	DET
bionys-568	55	9	lack	lack	NOUN
bionys-568	55	10	of	of	ADP
bionys-568	55	11	glucocorticoid	glucocorticoid	ADJ
bionys-568	55	12	recovery	recovery	NOUN
bionys-568	55	13	in	in	ADP
bionys-568	55	14	the	the	DET
bionys-568	55	15	liver	liver	NOUN
bionys-568	55	16	and	and	CCONJ
bionys-568	55	17	adipose	adipose	PRON
bionys-568	55	18	tissue	tissue	NOUN
bionys-568	55	19	provided	provide	VERB
bionys-568	55	20	a	a	DET
bionys-568	55	21	protective	protective	ADJ
bionys-568	55	22	effect	effect	NOUN
bionys-568	55	23	against	against	ADP
bionys-568	55	24	insulin	insulin	NOUN
bionys-568	55	25	resistance	resistance	NOUN
bionys-568	55	26	and	and	CCONJ
bionys-568	55	27	hyperglycemia	hyperglycemia	NOUN
bionys-568	55	28	(	(	PUNCT
bionys-568	55	29	kotelevtsev	kotelevtsev	PROPN
bionys-568	55	30	et	et	PROPN
bionys-568	55	31	al	al	PROPN
bionys-568	55	32	.	.	PROPN
bionys-568	55	33	,	,	PUNCT
bionys-568	55	34	1997	1997	NUM
bionys-568	55	35	;	;	PUNCT
bionys-568	55	36	morgan	morgan	PROPN
bionys-568	55	37	&	&	CCONJ
bionys-568	55	38	tomlinson	tomlinson	PROPN
bionys-568	55	39	,	,	PUNCT
bionys-568	55	40	2010	2010	NUM
bionys-568	55	41	)	)	PUNCT
bionys-568	55	42	.	.	PUNCT
bionys-568	56	1	one	one	NUM
bionys-568	56	2	single	single	ADJ
bionys-568	56	3	nucleotide	nucleotide	NOUN
bionys-568	56	4	polymorphism	polymorphism	NOUN
bionys-568	56	5	(	(	PUNCT
bionys-568	56	6	snp	snp	PROPN
bionys-568	56	7	)	)	PUNCT
bionys-568	56	8	of	of	ADP
bionys-568	56	9	the	the	DET
bionys-568	56	10	hsd11β1	hsd11β1	PROPN
bionys-568	56	11	quality	quality	NOUN
bionys-568	56	12	that	that	PRON
bionys-568	56	13	has	have	AUX
bionys-568	56	14	been	be	AUX
bionys-568	56	15	studied	study	VERB
bionys-568	56	16	is	be	AUX
bionys-568	56	17	rs846910	rs846910	NOUN
bionys-568	56	18	,	,	PUNCT
bionys-568	56	19	which	which	PRON
bionys-568	56	20	is	be	AUX
bionys-568	56	21	located	locate	VERB
bionys-568	56	22	in	in	ADP
bionys-568	56	23	the	the	DET
bionys-568	56	24	5	5	NUM
bionys-568	56	25	'	'	PART
bionys-568	56	26	promoter	promoter	NOUN
bionys-568	56	27	region	region	NOUN
bionys-568	56	28	of	of	ADP
bionys-568	56	29	the	the	DET
bionys-568	56	30	hsd11β1	hsd11β1	PROPN
bionys-568	56	31	gene	gene	NOUN
bionys-568	56	32	revealed	reveal	VERB
bionys-568	56	33	a	a	DET
bionys-568	56	34	conflicting	conflict	VERB
bionys-568	56	35	association	association	NOUN
bionys-568	56	36	between	between	ADP
bionys-568	56	37	metabolic	metabolic	NOUN
bionys-568	56	38	disorders	disorder	NOUN
bionys-568	56	39	and	and	CCONJ
bionys-568	56	40	type	type	NOUN
bionys-568	56	41	2	2	NUM
bionys-568	56	42	diabetes	diabetes	NOUN
bionys-568	56	43	in	in	ADP
bionys-568	56	44	different	different	ADJ
bionys-568	56	45	populations	population	NOUN
bionys-568	56	46	(	(	PUNCT
bionys-568	56	47	nair	nair	NOUN
bionys-568	56	48	et	et	PROPN
bionys-568	56	49	al	al	PROPN
bionys-568	56	50	.	.	PROPN
bionys-568	56	51	,	,	PUNCT
bionys-568	56	52	2004	2004	NUM
bionys-568	56	53	)	)	PUNCT
bionys-568	56	54	.	.	PUNCT
bionys-568	57	1	we	we	PRON
bionys-568	57	2	speculate	speculate	VERB
bionys-568	57	3	that	that	SCONJ
bionys-568	57	4	11β	11β	NOUN
bionys-568	57	5	-	-	PUNCT
bionys-568	57	6	hsd1	hsd1	ADJ
bionys-568	57	7	gene	gene	NOUN
bionys-568	57	8	polymorphisms	polymorphism	NOUN
bionys-568	57	9	,	,	PUNCT
bionys-568	57	10	particularly	particularly	ADV
bionys-568	57	11	rs846910	rs846910	NOUN
bionys-568	57	12	and	and	CCONJ
bionys-568	57	13	rs12086634	rs12086634	PROPN
bionys-568	57	14	,	,	PUNCT
bionys-568	57	15	may	may	AUX
bionys-568	57	16	be	be	AUX
bionys-568	57	17	linked	link	VERB
bionys-568	57	18	to	to	ADP
bionys-568	57	19	the	the	DET
bionys-568	57	20	onset	onset	NOUN
bionys-568	57	21	of	of	ADP
bionys-568	57	22	hcc	hcc	PROPN
bionys-568	57	23	based	base	VERB
bionys-568	57	24	on	on	ADP
bionys-568	57	25	the	the	DET
bionys-568	57	26	findings	finding	NOUN
bionys-568	57	27	of	of	ADP
bionys-568	57	28	this	this	DET
bionys-568	57	29	investigation	investigation	NOUN
bionys-568	57	30	.	.	PUNCT
bionys-568	58	1	materials	material	NOUN
bionys-568	58	2	and	and	CCONJ
bionys-568	58	3	methods	method	NOUN
bionys-568	58	4	this	this	DET
bionys-568	58	5	study	study	NOUN
bionys-568	58	6	included	include	VERB
bionys-568	58	7	150	150	NUM
bionys-568	58	8	samples	sample	NOUN
bionys-568	58	9	divided	divide	VERB
bionys-568	58	10	into	into	ADP
bionys-568	58	11	three	three	NUM
bionys-568	58	12	groups	group	NOUN
bionys-568	58	13	.	.	PUNCT
bionys-568	59	1	the	the	DET
bionys-568	59	2	first	first	ADJ
bionys-568	59	3	group	group	NOUN
bionys-568	59	4	included	include	VERB
bionys-568	59	5	50	50	NUM
bionys-568	59	6	samples	sample	NOUN
bionys-568	59	7	from	from	ADP
bionys-568	59	8	individuals	individual	NOUN
bionys-568	59	9	with	with	ADP
bionys-568	59	10	hepatocellular	hepatocellular	ADJ
bionys-568	59	11	carcinoma	carcinoma	NOUN
bionys-568	59	12	and	and	CCONJ
bionys-568	59	13	hepatitis	hepatitis	PROPN
bionys-568	59	14	b	b	PROPN
bionys-568	59	15	virus	virus	NOUN
bionys-568	59	16	carriers	carrier	NOUN
bionys-568	59	17	.	.	PUNCT
bionys-568	60	1	the	the	DET
bionys-568	60	2	second	second	ADJ
bionys-568	60	3	group	group	NOUN
bionys-568	60	4	included	include	VERB
bionys-568	60	5	50	50	NUM
bionys-568	60	6	samples	sample	NOUN
bionys-568	60	7	from	from	ADP
bionys-568	60	8	individuals	individual	NOUN
bionys-568	60	9	carrying	carry	VERB
bionys-568	60	10	only	only	ADV
bionys-568	60	11	hepatitis	hepatitis	PROPN
bionys-568	60	12	b	b	PROPN
bionys-568	60	13	virus	virus	NOUN
bionys-568	60	14	.	.	PUNCT
bionys-568	61	1	the	the	DET
bionys-568	61	2	third	third	ADJ
bionys-568	61	3	group	group	NOUN
bionys-568	61	4	included	include	VERB
bionys-568	61	5	50	50	NUM
bionys-568	61	6	samples	sample	NOUN
bionys-568	61	7	from	from	ADP
bionys-568	61	8	healthy	healthy	ADJ
bionys-568	61	9	individuals	individual	NOUN
bionys-568	61	10	.	.	PUNCT
bionys-568	62	1	samples	sample	NOUN
bionys-568	62	2	were	be	AUX
bionys-568	62	3	collected	collect	VERB
bionys-568	62	4	from	from	ADP
bionys-568	62	5	marjan	marjan	PROPN
bionys-568	62	6	teaching	teaching	NOUN
bionys-568	62	7	hospital	hospital	NOUN
bionys-568	62	8	in	in	ADP
bionys-568	62	9	the	the	DET
bionys-568	62	10	babylon	babylon	PROPN
bionys-568	62	11	governorate	governorate	PROPN
bionys-568	62	12	,	,	PUNCT
bionys-568	62	13	department	department	NOUN
bionys-568	62	14	of	of	ADP
bionys-568	62	15	oncology	oncology	NOUN
bionys-568	62	16	and	and	CCONJ
bionys-568	62	17	gastroenterology	gastroenterology	NOUN
bionys-568	62	18	,	,	PUNCT
bionys-568	62	19	between	between	ADP
bionys-568	62	20	2022	2022	NUM
bionys-568	62	21	and	and	CCONJ
bionys-568	62	22	2024	2024	NUM
bionys-568	62	23	.	.	PUNCT
bionys-568	63	1	ethical	ethical	ADJ
bionys-568	63	2	approval	approval	NOUN
bionys-568	63	3	was	be	AUX
bionys-568	63	4	obtained	obtain	VERB
bionys-568	63	5	from	from	ADP
bionys-568	63	6	the	the	DET
bionys-568	63	7	relevant	relevant	ADJ
bionys-568	63	8	committees	committee	NOUN
bionys-568	63	9	in	in	ADP
bionys-568	63	10	compliance	compliance	NOUN
bionys-568	63	11	with	with	ADP
bionys-568	63	12	the	the	DET
bionys-568	63	13	helsinki	helsinki	PROPN
bionys-568	63	14	principles	principle	NOUN
bionys-568	63	15	.	.	PUNCT
bionys-568	64	1	all	all	DET
bionys-568	64	2	participants	participant	NOUN
bionys-568	64	3	provided	provide	VERB
bionys-568	64	4	informed	informed	ADJ
bionys-568	64	5	consent	consent	NOUN
bionys-568	64	6	.	.	PUNCT
bionys-568	65	1	the	the	DET
bionys-568	65	2	control	control	PROPN
bionys-568	65	3	group	group	NOUN
bionys-568	65	4	comprised	comprise	VERB
bionys-568	65	5	50	50	NUM
bionys-568	65	6	healthy	healthy	ADJ
bionys-568	65	7	adults	adult	NOUN
bionys-568	65	8	devoid	devoid	ADJ
bionys-568	65	9	of	of	ADP
bionys-568	65	10	any	any	DET
bionys-568	65	11	history	history	NOUN
bionys-568	65	12	of	of	ADP
bionys-568	65	13	liver	liver	NOUN
bionys-568	65	14	disease	disease	NOUN
bionys-568	65	15	,	,	PUNCT
bionys-568	65	16	hypertension	hypertension	NOUN
bionys-568	65	17	,	,	PUNCT
bionys-568	65	18	renal	renal	ADJ
bionys-568	65	19	illness	illness	NOUN
bionys-568	65	20	,	,	PUNCT
bionys-568	65	21	diabetes	diabetes	NOUN
bionys-568	65	22	,	,	PUNCT
bionys-568	65	23	or	or	CCONJ
bionys-568	65	24	other	other	ADJ
bionys-568	65	25	chronic	chronic	ADJ
bionys-568	65	26	conditions	condition	NOUN
bionys-568	65	27	.	.	PUNCT
bionys-568	66	1	they	they	PRON
bionys-568	66	2	were	be	AUX
bionys-568	66	3	also	also	ADV
bionys-568	66	4	free	free	ADJ
bionys-568	66	5	of	of	ADP
bionys-568	66	6	hepatitis	hepatitis	PROPN
bionys-568	66	7	b	b	PROPN
bionys-568	66	8	or	or	CCONJ
bionys-568	66	9	c	c	PROPN
bionys-568	66	10	virus	virus	NOUN
bionys-568	66	11	infections	infection	NOUN
bionys-568	66	12	,	,	PUNCT
bionys-568	66	13	or	or	CCONJ
bionys-568	66	14	hiv	hiv	PROPN
bionys-568	66	15	.	.	PUNCT
bionys-568	67	1	there	there	PRON
bionys-568	67	2	were	be	VERB
bionys-568	67	3	25	25	NUM
bionys-568	67	4	males	male	NOUN
bionys-568	67	5	and	and	CCONJ
bionys-568	67	6	25	25	NUM
bionys-568	67	7	females	female	NOUN
bionys-568	67	8	among	among	ADP
bionys-568	67	9	the	the	DET
bionys-568	67	10	control	control	NOUN
bionys-568	67	11	group	group	NOUN
bionys-568	67	12	.	.	PUNCT
bionys-568	68	1	sample	sample	NOUN
bionys-568	68	2	collection	collection	NOUN
bionys-568	68	3	blood	blood	NOUN
bionys-568	68	4	samples	sample	NOUN
bionys-568	68	5	of	of	ADP
bionys-568	68	6	8	8	NUM
bionys-568	68	7	ml	ml	NOUN
bionys-568	68	8	were	be	AUX
bionys-568	68	9	collected	collect	VERB
bionys-568	68	10	from	from	ADP
bionys-568	68	11	each	each	DET
bionys-568	68	12	participant	participant	NOUN
bionys-568	68	13	and	and	CCONJ
bionys-568	68	14	processed	process	VERB
bionys-568	68	15	as	as	SCONJ
bionys-568	68	16	follows	follow	VERB
bionys-568	68	17	:	:	PUNCT
bionys-568	68	18	2	2	NUM
bionys-568	68	19	ml	ml	NOUN
bionys-568	68	20	were	be	AUX
bionys-568	68	21	placed	place	VERB
bionys-568	68	22	in	in	ADP
bionys-568	68	23	edta	edta	NOUN
bionys-568	68	24	tubes	tube	NOUN
bionys-568	68	25	for	for	ADP
bionys-568	68	26	dna	dna	PROPN
bionys-568	68	27	extraction	extraction	NOUN
bionys-568	68	28	,	,	PUNCT
bionys-568	68	29	2	2	NUM
bionys-568	68	30	ml	ml	NOUN
bionys-568	68	31	were	be	AUX
bionys-568	68	32	used	use	VERB
bionys-568	68	33	for	for	ADP
bionys-568	68	34	a	a	DET
bionys-568	68	35	complete	complete	ADJ
bionys-568	68	36	blood	blood	NOUN
bionys-568	68	37	count	count	NOUN
bionys-568	68	38	(	(	PUNCT
bionys-568	68	39	cbc	cbc	NOUN
bionys-568	68	40	)	)	PUNCT
bionys-568	68	41	analysis	analysis	NOUN
bionys-568	68	42	,	,	PUNCT
bionys-568	68	43	and	and	CCONJ
bionys-568	68	44	the	the	DET
bionys-568	68	45	remaining	remain	VERB
bionys-568	68	46	4	4	NUM
bionys-568	68	47	ml	ml	NOUN
bionys-568	68	48	were	be	AUX
bionys-568	68	49	placed	place	VERB
bionys-568	68	50	in	in	ADP
bionys-568	68	51	plain	plain	ADJ
bionys-568	68	52	biologica	biologica	PROPN
bionys-568	68	53	nyssana	nyssana	PROPN
bionys-568	69	1	●	●	PUNCT
bionys-568	69	2	16	16	NUM
bionys-568	69	3	(	(	PUNCT
bionys-568	69	4	1	1	NUM
bionys-568	69	5	)	)	PUNCT
bionys-568	69	6	june	june	PROPN
bionys-568	69	7	2025	2025	NUM
bionys-568	69	8	:	:	PUNCT
bionys-568	69	9	287	287	NUM
bionys-568	69	10	-	-	SYM
bionys-568	69	11	296	296	NUM
bionys-568	69	12	al	al	PROPN
bionys-568	69	13	-	-	PUNCT
bionys-568	69	14	khaykanee	khaykanee	PROPN
bionys-568	69	15	et	et	PROPN
bionys-568	69	16	al	al	PROPN
bionys-568	69	17	.	.	PUNCT
bionys-568	70	1	●	●	PUNCT
bionys-568	70	2	role	role	NOUN
bionys-568	70	3	of	of	ADP
bionys-568	70	4	11β	11β	PROPN
bionys-568	70	5	-	-	PUNCT
bionys-568	70	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	70	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	70	8	gene	gene	NOUN
bionys-568	70	9	polymorphisms	polymorphism	NOUN
bionys-568	70	10	rs846910	rs846910	NOUN
bionys-568	70	11	and	and	CCONJ
bionys-568	70	12	rs12086634	rs12086634	PROPN
bionys-568	70	13	in	in	ADP
bionys-568	70	14	the	the	DET
bionys-568	70	15	etiology	etiology	NOUN
bionys-568	70	16	of	of	ADP
bionys-568	70	17	hepatocellular	hepatocellular	ADJ
bionys-568	70	18	carcinoma	carcinoma	NOUN
bionys-568	70	19	289	289	NUM
bionys-568	70	20	biologica	biologica	NOUN
bionys-568	70	21	nyssana	nyssana	PROPN
bionys-568	70	22	●	●	PUNCT
bionys-568	70	23	16	16	NUM
bionys-568	70	24	(	(	PUNCT
bionys-568	70	25	1	1	NUM
bionys-568	70	26	)	)	PUNCT
bionys-568	70	27	june	june	PROPN
bionys-568	70	28	2025	2025	NUM
bionys-568	70	29	:	:	PUNCT
bionys-568	70	30	287	287	NUM
bionys-568	70	31	-	-	SYM
bionys-568	70	32	296	296	NUM
bionys-568	70	33	al	al	PROPN
bionys-568	70	34	-	-	PUNCT
bionys-568	70	35	khaykanee	khaykanee	PROPN
bionys-568	70	36	et	et	PROPN
bionys-568	70	37	al	al	PROPN
bionys-568	70	38	.	.	PUNCT
bionys-568	71	1	●	●	PUNCT
bionys-568	71	2	role	role	NOUN
bionys-568	71	3	of	of	ADP
bionys-568	71	4	11β	11β	PROPN
bionys-568	71	5	-	-	PUNCT
bionys-568	71	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	71	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	71	8	gene	gene	NOUN
bionys-568	71	9	polymorphisms	polymorphism	NOUN
bionys-568	71	10	rs846910	rs846910	NOUN
bionys-568	71	11	and	and	CCONJ
bionys-568	71	12	rs12086634	rs12086634	PROPN
bionys-568	71	13	in	in	ADP
bionys-568	71	14	the	the	DET
bionys-568	71	15	etiology	etiology	NOUN
bionys-568	71	16	of	of	ADP
bionys-568	71	17	hepatocellular	hepatocellular	ADJ
bionys-568	71	18	carcinoma	carcinoma	NOUN
bionys-568	71	19	tubes	tube	NOUN
bionys-568	71	20	,	,	PUNCT
bionys-568	71	21	allowed	allow	VERB
bionys-568	71	22	to	to	PART
bionys-568	71	23	clot	clot	VERB
bionys-568	71	24	for	for	ADP
bionys-568	71	25	15	15	NUM
bionys-568	71	26	minutes	minute	NOUN
bionys-568	71	27	,	,	PUNCT
bionys-568	71	28	centrifuged	centrifuge	VERB
bionys-568	71	29	at	at	ADP
bionys-568	71	30	3000	3000	NUM
bionys-568	71	31	rpm	rpm	NOUN
bionys-568	71	32	for	for	ADP
bionys-568	71	33	10	10	NUM
bionys-568	71	34	minutes	minute	NOUN
bionys-568	71	35	,	,	PUNCT
bionys-568	71	36	and	and	CCONJ
bionys-568	71	37	then	then	ADV
bionys-568	71	38	divided	divide	VERB
bionys-568	71	39	into	into	ADP
bionys-568	71	40	aliquots	aliquot	NOUN
bionys-568	71	41	for	for	ADP
bionys-568	71	42	liver	liver	NOUN
bionys-568	71	43	function	function	NOUN
bionys-568	71	44	testing	testing	NOUN
bionys-568	71	45	.	.	PUNCT
bionys-568	72	1	hepatitis	hepatitis	NOUN
bionys-568	72	2	markers	marker	NOUN
bionys-568	72	3	and	and	CCONJ
bionys-568	72	4	alpha	alpha	NOUN
bionys-568	72	5	-	-	PUNCT
bionys-568	72	6	fetoprotein	fetoprotein	ADJ
bionys-568	72	7	(	(	PUNCT
bionys-568	72	8	afp	afp	NOUN
bionys-568	72	9	)	)	PUNCT
bionys-568	72	10	were	be	AUX
bionys-568	72	11	analyzed	analyze	VERB
bionys-568	72	12	using	use	VERB
bionys-568	72	13	an	an	DET
bionys-568	72	14	electrochemiluminescence	electrochemiluminescence	NOUN
bionys-568	72	15	assay	assay	NOUN
bionys-568	72	16	(	(	PUNCT
bionys-568	72	17	ecla	ecla	NOUN
bionys-568	72	18	)	)	PUNCT
bionys-568	72	19	,	,	PUNCT
bionys-568	72	20	and	and	CCONJ
bionys-568	72	21	hbv	hbv	NOUN
bionys-568	72	22	-	-	PUNCT
bionys-568	72	23	rna	rna	NOUN
bionys-568	72	24	quantification	quantification	NOUN
bionys-568	72	25	was	be	AUX
bionys-568	72	26	performed	perform	VERB
bionys-568	72	27	using	use	VERB
bionys-568	72	28	the	the	DET
bionys-568	72	29	cobas	cobas	ADJ
bionys-568	72	30	taqman	taqman	NOUN
bionys-568	72	31	hbv	hbv	PROPN
bionys-568	72	32	quantitative	quantitative	ADJ
bionys-568	72	33	assay	assay	PROPN
bionys-568	72	34	,	,	PUNCT
bionys-568	72	35	version	version	NOUN
bionys-568	72	36	2.0	2.0	NUM
bionys-568	72	37	.	.	PUNCT
bionys-568	73	1	hbv	hbv	NOUN
bionys-568	73	2	genotypes	genotype	NOUN
bionys-568	73	3	were	be	AUX
bionys-568	73	4	determined	determine	VERB
bionys-568	73	5	using	use	VERB
bionys-568	73	6	the	the	DET
bionys-568	73	7	linear	linear	ADJ
bionys-568	73	8	probe	probe	NOUN
bionys-568	73	9	assay	assay	VERB
bionys-568	73	10	with	with	ADP
bionys-568	73	11	the	the	DET
bionys-568	73	12	inno	inno	PROPN
bionys-568	73	13	-	-	PUNCT
bionys-568	73	14	lipa	lipa	NOUN
bionys-568	73	15	hbv	hbv	NOUN
bionys-568	73	16	2	2	NUM
bionys-568	73	17	kit	kit	NOUN
bionys-568	73	18	from	from	ADP
bionys-568	73	19	innogenetics	innogenetic	NOUN
bionys-568	73	20	(	(	PUNCT
bionys-568	73	21	uk	uk	PROPN
bionys-568	73	22	)	)	PUNCT
bionys-568	73	23	.	.	PUNCT
bionys-568	74	1	snp	snp	PROPN
bionys-568	74	2	assay	assay	PROPN
bionys-568	74	3	of	of	ADP
bionys-568	74	4	11β	11β	NUM
bionys-568	74	5	hsd1	hsd1	VERB
bionys-568	74	6	rs846910	rs846910	NOUN
bionys-568	74	7	and	and	CCONJ
bionys-568	74	8	rs12086634	rs12086634	PROPN
bionys-568	74	9	and	and	CCONJ
bionys-568	74	10	dna	dna	PROPN
bionys-568	74	11	extraction	extraction	NOUN
bionys-568	74	12	genomic	genomic	NOUN
bionys-568	74	13	dna	dna	PROPN
bionys-568	74	14	was	be	AUX
bionys-568	74	15	extracted	extract	VERB
bionys-568	74	16	using	use	VERB
bionys-568	74	17	purelink	purelink	NOUN
bionys-568	74	18	genomic	genomic	ADJ
bionys-568	74	19	dna	dna	PROPN
bionys-568	74	20	extraction	extraction	NOUN
bionys-568	74	21	kits	kit	NOUN
bionys-568	74	22	(	(	PUNCT
bionys-568	74	23	usa	usa	PROPN
bionys-568	74	24	)	)	PUNCT
bionys-568	74	25	according	accord	VERB
bionys-568	74	26	to	to	ADP
bionys-568	74	27	the	the	DET
bionys-568	74	28	manufacturer	manufacturer	NOUN
bionys-568	74	29	's	's	PART
bionys-568	74	30	instructions	instruction	NOUN
bionys-568	74	31	(	(	PUNCT
bionys-568	74	32	qiagen	qiagen	PROPN
bionys-568	74	33	)	)	PUNCT
bionys-568	74	34	.	.	PUNCT
bionys-568	75	1	single	single	ADJ
bionys-568	75	2	nucleotide	nucleotide	ADJ
bionys-568	75	3	polymorphism	polymorphism	NOUN
bionys-568	75	4	(	(	PUNCT
bionys-568	75	5	snp	snp	NOUN
bionys-568	75	6	)	)	PUNCT
bionys-568	75	7	assays	assay	NOUN
bionys-568	75	8	for	for	ADP
bionys-568	75	9	11β	11β	NOUN
bionys-568	75	10	-	-	PUNCT
bionys-568	75	11	hsd1	hsd1	ADJ
bionys-568	75	12	rs846910	rs846910	NOUN
bionys-568	75	13	and	and	CCONJ
bionys-568	75	14	rs12086634	rs12086634	PROPN
bionys-568	75	15	were	be	AUX
bionys-568	75	16	conducted	conduct	VERB
bionys-568	75	17	using	use	VERB
bionys-568	75	18	taqman	taqman	NOUN
bionys-568	75	19	genotyping	genotype	VERB
bionys-568	75	20	test	test	NOUN
bionys-568	75	21	kits	kit	NOUN
bionys-568	75	22	with	with	ADP
bionys-568	75	23	the	the	DET
bionys-568	75	24	applied	apply	VERB
bionys-568	75	25	biosystems	biosystem	NOUN
bionys-568	75	26	7500	7500	NUM
bionys-568	75	27	real	real	ADJ
bionys-568	75	28	-	-	PUNCT
bionys-568	75	29	time	time	NOUN
bionys-568	75	30	pcr	pcr	PROPN
bionys-568	75	31	instrument	instrument	NOUN
bionys-568	75	32	(	(	PUNCT
bionys-568	75	33	foster	foster	ADJ
bionys-568	75	34	city	city	NOUN
bionys-568	75	35	,	,	PUNCT
bionys-568	75	36	ca	ca	PROPN
bionys-568	75	37	,	,	PUNCT
bionys-568	75	38	usa	usa	PROPN
bionys-568	75	39	)	)	PUNCT
bionys-568	75	40	.	.	PUNCT
bionys-568	76	1	the	the	DET
bionys-568	76	2	primer	primer	NOUN
bionys-568	76	3	and	and	CCONJ
bionys-568	76	4	probe	probe	VERB
bionys-568	76	5	sequences	sequence	NOUN
bionys-568	76	6	for	for	ADP
bionys-568	76	7	11β	11β	NOUN
bionys-568	76	8	-	-	PUNCT
bionys-568	76	9	hsd1	hsd1	ADJ
bionys-568	76	10	rs846910	rs846910	NOUN
bionys-568	76	11	were	be	AUX
bionys-568	76	12	as	as	SCONJ
bionys-568	76	13	follows	follow	VERB
bionys-568	76	14	:	:	PUNCT
bionys-568	76	15	forward	forward	ADJ
bionys-568	76	16	primer	primer	NOUN
bionys-568	76	17	5′-ctctgttgcttgcttgcttgattc-3′	5′-ctctgttgcttgcttgcttgattc-3′	NUM
bionys-568	76	18	,	,	PUNCT
bionys-568	76	19	reverse	reverse	ADJ
bionys-568	76	20	primer	primer	NOUN
bionys-568	76	21	5	5	NUM
bionys-568	76	22	′	′	NUM
bionys-568	76	23	-agagcaggctttcagcaga	-agagcaggctttcagcaga	NOUN
bionys-568	76	24	ta-3′	ta-3′	PROPN
bionys-568	76	25	,	,	PUNCT
bionys-568	76	26	and	and	CCONJ
bionys-568	76	27	probe	probe	VERB
bionys-568	76	28	5	5	NUM
bionys-568	76	29	′	′	NOUN
bionys-568	76	30	-ctggtgggaat[vic]/	-ctggtgggaat[vic]/	PUNCT
bionys-568	77	1	[	[	X
bionys-568	77	2	fam]tcaaatcagagaga-3′	fam]tcaaatcagagaga-3′	NOUN
bionys-568	77	3	(	(	PUNCT
bionys-568	77	4	genbank	genbank	PROPN
bionys-568	77	5	nc_000001.11:209701908	nc_000001.11:209701908	PROPN
bionys-568	77	6	:	:	PUNCT
bionys-568	77	7	a	a	DET
bionys-568	77	8	:	:	PUNCT
bionys-568	77	9	g	g	NOUN
bionys-568	77	10	)	)	PUNCT
bionys-568	77	11	.	.	PUNCT
bionys-568	78	1	for	for	ADP
bionys-568	78	2	11β	11β	NOUN
bionys-568	78	3	-	-	PUNCT
bionys-568	78	4	hsd1	hsd1	PROPN
bionys-568	78	5	rs12086634	rs12086634	PROPN
bionys-568	78	6	,	,	PUNCT
bionys-568	78	7	the	the	DET
bionys-568	78	8	forward	forward	ADJ
bionys-568	78	9	primer	primer	NOUN
bionys-568	78	10	was	be	AUX
bionys-568	78	11	5	5	NUM
bionys-568	78	12	′	′	NUM
bionys-568	78	13	-ggaggagaatgggaaaggtat	-ggaggagaatgggaaaggtat	PROPN
bionys-568	78	14	caac-3′	caac-3′	NOUN
bionys-568	78	15	,	,	PUNCT
bionys-568	78	16	the	the	DET
bionys-568	78	17	reverse	reverse	ADJ
bionys-568	78	18	primer	primer	NOUN
bionys-568	78	19	was	be	AUX
bionys-568	78	20	5	5	NUM
bionys-568	78	21	′	′	NUM
bionys-568	78	22	-tcctcctgcaagagatggctatatt-3′	-tcctcctgcaagagatggctatatt-3′	ADJ
bionys-568	78	23	,	,	PUNCT
bionys-568	78	24	and	and	CCONJ
bionys-568	78	25	the	the	DET
bionys-568	78	26	probe	probe	NOUN
bionys-568	78	27	was	be	AUX
bionys-568	78	28	5	5	NUM
bionys-568	78	29	′	′	NUM
bionys-568	78	30	-cccagaggatttct[vic]/	-cccagaggatttct[vic]/	PUNCT
bionys-568	79	1	[	[	PUNCT
bionys-568	79	2	f	f	X
bionys-568	79	3	a	a	PRON
bionys-568	79	4	m	m	NOUN
bionys-568	79	5	]	]	X
bionys-568	79	6	c	c	X
bionys-568	79	7	a	a	DET
bionys-568	79	8	g	g	NOUN
bionys-568	79	9	a	a	DET
bionys-568	79	10	t	t	NOUN
bionys-568	79	11	g	g	PROPN
bionys-568	79	12	a	a	DET
bionys-568	79	13	t	t	NOUN
bionys-568	79	14	t	t	NOUN
bionys-568	79	15	t	t	PROPN
bionys-568	79	16	c	c	PROPN
bionys-568	79	17	t	t	PROPN
bionys-568	79	18	3	3	NUM
bionys-568	79	19	′	′	NUM
bionys-568	79	20	(	(	PUNCT
bionys-568	79	21	g	g	NOUN
bionys-568	79	22	e	e	PROPN
bionys-568	79	23	n	n	PROPN
bionys-568	79	24	b	b	PROPN
bionys-568	79	25	a	a	PRON
bionys-568	79	26	n	n	PRON
bionys-568	79	27	k	k	NOUN
bionys-568	79	28	nc_000001.11:209706913	nc_000001.11:209706913	PROPN
bionys-568	79	29	:	:	PUNCT
bionys-568	79	30	t	t	NOUN
bionys-568	79	31	:	:	PUNCT
bionys-568	79	32	g	g	NOUN
bionys-568	79	33	)	)	PUNCT
bionys-568	79	34	.	.	PUNCT
bionys-568	80	1	the	the	DET
bionys-568	80	2	pcr	pcr	PROPN
bionys-568	80	3	reaction	reaction	NOUN
bionys-568	80	4	(	(	PUNCT
bionys-568	80	5	25	25	NUM
bionys-568	80	6	µl	µl	NOUN
bionys-568	80	7	)	)	PUNCT
bionys-568	80	8	mixture	mixture	NOUN
bionys-568	80	9	contained	contain	VERB
bionys-568	80	10	12.5	12.5	NUM
bionys-568	80	11	µl	µl	NOUN
bionys-568	80	12	of	of	ADP
bionys-568	80	13	taqman	taqman	NOUN
bionys-568	80	14	master	master	PROPN
bionys-568	80	15	mix	mix	PROPN
bionys-568	80	16	,	,	PUNCT
bionys-568	80	17	1.25	1.25	NUM
bionys-568	80	18	µl	µl	NOUN
bionys-568	80	19	of	of	ADP
bionys-568	80	20	the	the	DET
bionys-568	80	21	snp	snp	NOUN
bionys-568	80	22	assay	assay	NOUN
bionys-568	80	23	,	,	PUNCT
bionys-568	80	24	6.25	6.25	NUM
bionys-568	80	25	µl	µl	NOUN
bionys-568	80	26	of	of	ADP
bionys-568	80	27	nuclease	nuclease	NOUN
bionys-568	80	28	-	-	PUNCT
bionys-568	80	29	free	free	ADJ
bionys-568	80	30	water	water	NOUN
bionys-568	80	31	,	,	PUNCT
bionys-568	80	32	and	and	CCONJ
bionys-568	80	33	5	5	NUM
bionys-568	80	34	µl	µl	NOUN
bionys-568	80	35	(	(	PUNCT
bionys-568	80	36	10	10	NUM
bionys-568	80	37	ng/µl	ng/µl	NUM
bionys-568	80	38	)	)	PUNCT
bionys-568	80	39	of	of	ADP
bionys-568	80	40	genomic	genomic	ADJ
bionys-568	80	41	dna	dna	PROPN
bionys-568	80	42	template	template	NOUN
bionys-568	80	43	.	.	PUNCT
bionys-568	81	1	negative	negative	ADJ
bionys-568	81	2	controls	control	NOUN
bionys-568	81	3	included	include	VERB
bionys-568	81	4	5	5	NUM
bionys-568	81	5	µl	µl	NOUN
bionys-568	81	6	of	of	ADP
bionys-568	81	7	dnase	dnase	NOUN
bionys-568	81	8	-	-	PUNCT
bionys-568	81	9	free	free	ADJ
bionys-568	81	10	water	water	NOUN
bionys-568	81	11	.	.	PUNCT
bionys-568	82	1	the	the	DET
bionys-568	82	2	mixture	mixture	NOUN
bionys-568	82	3	was	be	AUX
bionys-568	82	4	thoroughly	thoroughly	ADV
bionys-568	82	5	mixed	mixed	ADJ
bionys-568	82	6	,	,	PUNCT
bionys-568	82	7	centrifuged	centrifuge	VERB
bionys-568	82	8	briefly	briefly	ADV
bionys-568	82	9	,	,	PUNCT
bionys-568	82	10	and	and	CCONJ
bionys-568	82	11	loaded	load	VERB
bionys-568	82	12	onto	onto	ADP
bionys-568	82	13	the	the	DET
bionys-568	82	14	pcr	pcr	ADJ
bionys-568	82	15	cycler	cycler	NOUN
bionys-568	82	16	(	(	PUNCT
bionys-568	82	17	applied	apply	VERB
bionys-568	82	18	bio	bio	PROPN
bionys-568	82	19	systems	systems	PROPN
bionys-568	82	20	®	®	PROPN
bionys-568	82	21	7500	7500	NUM
bionys-568	82	22	real	real	ADJ
bionys-568	82	23	-	-	PUNCT
bionys-568	82	24	time	time	NOUN
bionys-568	82	25	pcr	pcr	NOUN
bionys-568	82	26	)	)	PUNCT
bionys-568	82	27	.	.	PUNCT
bionys-568	83	1	genotypes	genotype	NOUN
bionys-568	83	2	were	be	AUX
bionys-568	83	3	determined	determine	VERB
bionys-568	83	4	using	use	VERB
bionys-568	83	5	the	the	DET
bionys-568	83	6	taqman	taqman	NOUN
bionys-568	83	7	allelic	allelic	ADJ
bionys-568	83	8	discrimination	discrimination	NOUN
bionys-568	83	9	test	test	NOUN
bionys-568	83	10	,	,	PUNCT
bionys-568	83	11	and	and	CCONJ
bionys-568	83	12	unidentified	unidentified	ADJ
bionys-568	83	13	samples	sample	NOUN
bionys-568	83	14	were	be	AUX
bionys-568	83	15	categorized	categorize	VERB
bionys-568	83	16	as	as	ADP
bionys-568	83	17	homozygous	homozygous	ADJ
bionys-568	83	18	or	or	CCONJ
bionys-568	83	19	heterozygous	heterozygous	ADJ
bionys-568	83	20	based	base	VERB
bionys-568	83	21	on	on	ADP
bionys-568	83	22	allelic	allelic	ADJ
bionys-568	83	23	differentiation	differentiation	NOUN
bionys-568	83	24	analysis	analysis	NOUN
bionys-568	83	25	.	.	PUNCT
bionys-568	84	1	laboratory	laboratory	NOUN
bionys-568	84	2	analyses	analyse	VERB
bionys-568	84	3	liver	liver	NOUN
bionys-568	84	4	function	function	NOUN
bionys-568	84	5	tests	test	NOUN
bionys-568	84	6	included	include	VERB
bionys-568	84	7	the	the	DET
bionys-568	84	8	measurement	measurement	NOUN
bionys-568	84	9	of	of	ADP
bionys-568	84	10	alkaline	alkaline	NOUN
bionys-568	84	11	phosphatase	phosphatase	NOUN
bionys-568	84	12	(	(	PUNCT
bionys-568	84	13	alp	alp	PROPN
bionys-568	84	14	)	)	PUNCT
bionys-568	84	15	,	,	PUNCT
bionys-568	84	16	albumin	albumin	NOUN
bionys-568	84	17	,	,	PUNCT
bionys-568	84	18	total	total	ADJ
bionys-568	84	19	protein	protein	NOUN
bionys-568	84	20	,	,	PUNCT
bionys-568	84	21	aspartate	aspartate	NOUN
bionys-568	84	22	aminotransferase	aminotransferase	NOUN
bionys-568	84	23	(	(	PUNCT
bionys-568	84	24	ast	ast	NOUN
bionys-568	84	25	)	)	PUNCT
bionys-568	84	26	,	,	PUNCT
bionys-568	84	27	and	and	CCONJ
bionys-568	84	28	alanine	alanine	NOUN
bionys-568	84	29	aminotransferase	aminotransferase	PROPN
bionys-568	84	30	(	(	PUNCT
bionys-568	84	31	alt	alt	ADJ
bionys-568	84	32	)	)	PUNCT
bionys-568	84	33	using	use	VERB
bionys-568	84	34	the	the	DET
bionys-568	84	35	monarch-240	monarch-240	ADJ
bionys-568	84	36	clinical	clinical	ADJ
bionys-568	84	37	chemistry	chemistry	NOUN
bionys-568	84	38	analyzer	analyzer	NOUN
bionys-568	84	39	.	.	PUNCT
bionys-568	85	1	hepatitis	hepatitis	PROPN
bionys-568	85	2	b	b	PROPN
bionys-568	85	3	surface	surface	NOUN
bionys-568	85	4	antigen	antigen	NOUN
bionys-568	85	5	(	(	PUNCT
bionys-568	85	6	hbsag	hbsag	NOUN
bionys-568	85	7	)	)	PUNCT
bionys-568	85	8	was	be	AUX
bionys-568	85	9	assessed	assess	VERB
bionys-568	85	10	using	use	VERB
bionys-568	85	11	a	a	DET
bionys-568	85	12	chemiluminescence	chemiluminescence	NOUN
bionys-568	85	13	assay	assay	NOUN
bionys-568	85	14	kit	kit	NOUN
bionys-568	85	15	from	from	ADP
bionys-568	85	16	siemens	siemens	PROPN
bionys-568	85	17	healthcare	healthcare	PROPN
bionys-568	85	18	diagnostics	diagnostic	NOUN
bionys-568	85	19	.	.	PUNCT
bionys-568	86	1	cbc	cbc	PROPN
bionys-568	86	2	was	be	AUX
bionys-568	86	3	performed	perform	VERB
bionys-568	86	4	with	with	ADP
bionys-568	86	5	the	the	DET
bionys-568	86	6	sysmex	sysmex	NOUN
bionys-568	86	7	xp-300	xp-300	X
bionys-568	86	8	fully	fully	ADV
bionys-568	86	9	automated	automate	VERB
bionys-568	86	10	3	3	NUM
bionys-568	86	11	-	-	PUNCT
bionys-568	86	12	part	part	NOUN
bionys-568	86	13	cell	cell	NOUN
bionys-568	86	14	counter	counter	NOUN
bionys-568	86	15	(	(	PUNCT
bionys-568	86	16	japan	japan	PROPN
bionys-568	86	17	)	)	PUNCT
bionys-568	86	18	.	.	PUNCT
bionys-568	87	1	routine	routine	ADJ
bionys-568	87	2	assessments	assessment	NOUN
bionys-568	87	3	for	for	ADP
bionys-568	87	4	hepatic	hepatic	ADJ
bionys-568	87	5	and	and	CCONJ
bionys-568	87	6	renal	renal	ADJ
bionys-568	87	7	functions	function	NOUN
bionys-568	87	8	,	,	PUNCT
bionys-568	87	9	hepatitis	hepatitis	NOUN
bionys-568	87	10	markers	marker	NOUN
bionys-568	87	11	,	,	PUNCT
bionys-568	87	12	afp	afp	PROPN
bionys-568	87	13	measurement	measurement	NOUN
bionys-568	87	14	,	,	PUNCT
bionys-568	87	15	and	and	CCONJ
bionys-568	87	16	hbv	hbv	NOUN
bionys-568	87	17	-	-	PUNCT
bionys-568	87	18	rna	rna	NOUN
bionys-568	87	19	detection	detection	NOUN
bionys-568	87	20	were	be	AUX
bionys-568	87	21	conducted	conduct	VERB
bionys-568	87	22	for	for	ADP
bionys-568	87	23	all	all	DET
bionys-568	87	24	groups	group	NOUN
bionys-568	87	25	.	.	PUNCT
bionys-568	88	1	statical	statical	ADJ
bionys-568	88	2	analysis	analysis	NOUN
bionys-568	88	3	data	datum	NOUN
bionys-568	88	4	were	be	AUX
bionys-568	88	5	analyzed	analyze	VERB
bionys-568	88	6	using	use	VERB
bionys-568	88	7	spss	spss	PROPN
bionys-568	88	8	version	version	NOUN
bionys-568	88	9	20	20	NUM
bionys-568	88	10	.	.	PUNCT
bionys-568	89	1	numerical	numerical	PROPN
bionys-568	89	2	variables	variable	NOUN
bionys-568	89	3	were	be	AUX
bionys-568	89	4	expressed	express	VERB
bionys-568	89	5	as	as	ADP
bionys-568	89	6	mean	mean	NOUN
bionys-568	89	7	±	±	NUM
bionys-568	89	8	standard	standard	ADJ
bionys-568	89	9	deviation	deviation	NOUN
bionys-568	89	10	(	(	PUNCT
bionys-568	89	11	sd	sd	NOUN
bionys-568	89	12	)	)	PUNCT
bionys-568	89	13	,	,	PUNCT
bionys-568	89	14	while	while	SCONJ
bionys-568	89	15	categorical	categorical	ADJ
bionys-568	89	16	variables	variable	NOUN
bionys-568	89	17	were	be	AUX
bionys-568	89	18	presented	present	VERB
bionys-568	89	19	as	as	ADP
bionys-568	89	20	frequencies	frequency	NOUN
bionys-568	89	21	and	and	CCONJ
bionys-568	89	22	percentages	percentage	NOUN
bionys-568	89	23	.	.	PUNCT
bionys-568	90	1	the	the	DET
bionys-568	90	2	mann	mann	PROPN
bionys-568	90	3	-	-	PUNCT
bionys-568	90	4	whitney	whitney	PROPN
bionys-568	90	5	u	u	PROPN
bionys-568	90	6	test	test	NOUN
bionys-568	90	7	was	be	AUX
bionys-568	90	8	employed	employ	VERB
bionys-568	90	9	to	to	PART
bionys-568	90	10	compare	compare	VERB
bionys-568	90	11	nonparametric	nonparametric	NOUN
bionys-568	90	12	variables	variable	NOUN
bionys-568	90	13	between	between	ADP
bionys-568	90	14	two	two	NUM
bionys-568	90	15	groups	group	NOUN
bionys-568	90	16	,	,	PUNCT
bionys-568	90	17	and	and	CCONJ
bionys-568	90	18	the	the	DET
bionys-568	90	19	chi	chi	ADJ
bionys-568	90	20	-	-	PUNCT
bionys-568	90	21	square	square	ADJ
bionys-568	90	22	test	test	NOUN
bionys-568	90	23	was	be	AUX
bionys-568	90	24	used	use	VERB
bionys-568	90	25	to	to	PART
bionys-568	90	26	compare	compare	VERB
bionys-568	90	27	categorical	categorical	ADJ
bionys-568	90	28	variables	variable	NOUN
bionys-568	90	29	.	.	PUNCT
bionys-568	91	1	correlations	correlation	NOUN
bionys-568	91	2	between	between	ADP
bionys-568	91	3	numerical	numerical	ADJ
bionys-568	91	4	variables	variable	NOUN
bionys-568	91	5	were	be	AUX
bionys-568	91	6	analyzed	analyze	VERB
bionys-568	91	7	using	use	VERB
bionys-568	91	8	spearman	spearman	NOUN
bionys-568	91	9	's	's	PART
bionys-568	91	10	correlation	correlation	NOUN
bionys-568	91	11	coefficient	coefficient	NOUN
bionys-568	91	12	(	(	PUNCT
bionys-568	91	13	rs	rs	NOUN
bionys-568	91	14	)	)	PUNCT
bionys-568	91	15	.	.	PUNCT
bionys-568	92	1	ors	or	NOUN
bionys-568	92	2	were	be	AUX
bionys-568	92	3	calculated	calculate	VERB
bionys-568	92	4	using	use	VERB
bionys-568	92	5	logistic	logistic	ADJ
bionys-568	92	6	regression	regression	NOUN
bionys-568	92	7	with	with	ADP
bionys-568	92	8	ci	ci	PROPN
bionys-568	92	9	95	95	NUM
bionys-568	92	10	%	%	NOUN
bionys-568	92	11	.	.	PUNCT
bionys-568	93	1	a	a	DET
bionys-568	93	2	p	p	NOUN
bionys-568	93	3	-	-	PUNCT
bionys-568	93	4	value≤0.05	value≤0.05	NOUN
bionys-568	93	5	was	be	AUX
bionys-568	93	6	considered	consider	VERB
bionys-568	93	7	statistically	statistically	ADV
bionys-568	93	8	significant	significant	ADJ
bionys-568	93	9	,	,	PUNCT
bionys-568	93	10	with	with	ADP
bionys-568	93	11	p<0.01	p<0.01	PROPN
bionys-568	93	12	indicating	indicate	VERB
bionys-568	93	13	a	a	DET
bionys-568	93	14	highly	highly	ADV
bionys-568	93	15	significant	significant	ADJ
bionys-568	93	16	result	result	NOUN
bionys-568	93	17	.	.	PUNCT
bionys-568	94	1	results	result	NOUN
bionys-568	94	2	and	and	CCONJ
bionys-568	94	3	discussion	discussion	NOUN
bionys-568	94	4	this	this	DET
bionys-568	94	5	study	study	NOUN
bionys-568	94	6	included	include	VERB
bionys-568	94	7	150	150	NUM
bionys-568	94	8	samples	sample	NOUN
bionys-568	94	9	,	,	PUNCT
bionys-568	94	10	consisting	consist	VERB
bionys-568	94	11	of	of	ADP
bionys-568	94	12	50	50	NUM
bionys-568	94	13	patients	patient	NOUN
bionys-568	94	14	with	with	ADP
bionys-568	94	15	hepatocellular	hepatocellular	ADJ
bionys-568	94	16	carcinoma	carcinoma	NOUN
bionys-568	94	17	(	(	PUNCT
bionys-568	94	18	hcc	hcc	PROPN
bionys-568	94	19	)	)	PUNCT
bionys-568	94	20	and	and	CCONJ
bionys-568	94	21	hepatitis	hepatitis	PROPN
bionys-568	94	22	b	b	PROPN
bionys-568	94	23	virus	virus	NOUN
bionys-568	94	24	(	(	PUNCT
bionys-568	94	25	hbv	hbv	NOUN
bionys-568	94	26	)	)	PUNCT
bionys-568	94	27	,	,	PUNCT
bionys-568	94	28	50	50	NUM
bionys-568	94	29	patients	patient	NOUN
bionys-568	94	30	with	with	ADP
bionys-568	94	31	hbv	hbv	NOUN
bionys-568	94	32	infection	infection	NOUN
bionys-568	94	33	,	,	PUNCT
bionys-568	94	34	and	and	CCONJ
bionys-568	94	35	50	50	NUM
bionys-568	94	36	healthy	healthy	ADJ
bionys-568	94	37	controls	control	NOUN
bionys-568	94	38	.	.	PUNCT
bionys-568	95	1	the	the	DET
bionys-568	95	2	demographic	demographic	ADJ
bionys-568	95	3	and	and	CCONJ
bionys-568	95	4	laboratory	laboratory	NOUN
bionys-568	95	5	data	datum	NOUN
bionys-568	95	6	for	for	ADP
bionys-568	95	7	the	the	DET
bionys-568	95	8	patient	patient	ADJ
bionys-568	95	9	and	and	CCONJ
bionys-568	95	10	control	control	NOUN
bionys-568	95	11	groups	group	NOUN
bionys-568	95	12	are	be	AUX
bionys-568	95	13	summarized	summarize	VERB
bionys-568	95	14	in	in	ADP
bionys-568	95	15	tab	tab	NOUN
bionys-568	95	16	.	.	PUNCT
bionys-568	96	1	1	1	X
bionys-568	96	2	.	.	X
bionys-568	96	3	no	no	DET
bionys-568	96	4	statistically	statistically	ADV
bionys-568	96	5	significant	significant	ADJ
bionys-568	96	6	differences	difference	NOUN
bionys-568	96	7	were	be	AUX
bionys-568	96	8	observed	observe	VERB
bionys-568	96	9	for	for	ADP
bionys-568	96	10	age	age	NOUN
bionys-568	96	11	and	and	CCONJ
bionys-568	96	12	sex	sex	NOUN
bionys-568	96	13	between	between	ADP
bionys-568	96	14	the	the	DET
bionys-568	96	15	groups	group	NOUN
bionys-568	96	16	,	,	PUNCT
bionys-568	96	17	indicating	indicate	VERB
bionys-568	96	18	adequate	adequate	ADJ
bionys-568	96	19	matching	matching	NOUN
bionys-568	96	20	.	.	PUNCT
bionys-568	97	1	however	however	ADV
bionys-568	97	2	,	,	PUNCT
bionys-568	97	3	statistically	statistically	ADV
bionys-568	97	4	significant	significant	ADJ
bionys-568	97	5	differences	difference	NOUN
bionys-568	97	6	were	be	AUX
bionys-568	97	7	detected	detect	VERB
bionys-568	97	8	between	between	ADP
bionys-568	97	9	the	the	DET
bionys-568	97	10	hbv	hbv	PROPN
bionys-568	97	11	and	and	CCONJ
bionys-568	97	12	hcc	hcc	PROPN
bionys-568	97	13	groups	group	NOUN
bionys-568	97	14	compared	compare	VERB
bionys-568	97	15	to	to	ADP
bionys-568	97	16	the	the	DET
bionys-568	97	17	controls	control	NOUN
bionys-568	97	18	regarding	regard	VERB
bionys-568	97	19	the	the	DET
bionys-568	97	20	laboratory	laboratory	NOUN
bionys-568	97	21	tests	test	NOUN
bionys-568	97	22	(	(	PUNCT
bionys-568	97	23	tab	tab	NOUN
bionys-568	97	24	.	.	NOUN
bionys-568	97	25	1	1	NUM
bionys-568	97	26	)	)	PUNCT
bionys-568	97	27	.	.	PUNCT
bionys-568	98	1	the	the	DET
bionys-568	98	2	results	result	NOUN
bionys-568	98	3	revealed	reveal	VERB
bionys-568	98	4	significant	significant	ADJ
bionys-568	98	5	differences	difference	NOUN
bionys-568	98	6	in	in	ADP
bionys-568	98	7	the	the	DET
bionys-568	98	8	distribution	distribution	NOUN
bionys-568	98	9	of	of	ADP
bionys-568	98	10	genotypes	genotype	NOUN
bionys-568	98	11	and	and	CCONJ
bionys-568	98	12	alleles	allele	NOUN
bionys-568	98	13	for	for	ADP
bionys-568	98	14	the	the	DET
bionys-568	98	15	rs12086634	rs12086634	PROPN
bionys-568	98	16	and	and	CCONJ
bionys-568	98	17	rs846910	rs846910	PROPN
bionys-568	98	18	polymorphisms	polymorphism	NOUN
bionys-568	98	19	among	among	ADP
bionys-568	98	20	the	the	DET
bionys-568	98	21	hbv	hbv	NOUN
bionys-568	98	22	,	,	PUNCT
bionys-568	98	23	hcc	hcc	PROPN
bionys-568	98	24	,	,	PUNCT
bionys-568	98	25	and	and	CCONJ
bionys-568	98	26	control	control	NOUN
bionys-568	98	27	groups	group	NOUN
bionys-568	98	28	,	,	PUNCT
bionys-568	98	29	suggesting	suggest	VERB
bionys-568	98	30	a	a	DET
bionys-568	98	31	potential	potential	ADJ
bionys-568	98	32	association	association	NOUN
bionys-568	98	33	between	between	ADP
bionys-568	98	34	these	these	DET
bionys-568	98	35	polymorphisms	polymorphism	NOUN
bionys-568	98	36	and	and	CCONJ
bionys-568	98	37	the	the	DET
bionys-568	98	38	development	development	NOUN
bionys-568	98	39	of	of	ADP
bionys-568	98	40	hbv	hbv	NOUN
bionys-568	98	41	and	and	CCONJ
bionys-568	98	42	hcc	hcc	PROPN
bionys-568	98	43	(	(	PUNCT
bionys-568	98	44	tab	tab	NOUN
bionys-568	98	45	.	.	NOUN
bionys-568	98	46	2	2	NUM
bionys-568	98	47	)	)	PUNCT
bionys-568	98	48	.	.	PUNCT
bionys-568	99	1	in	in	ADP
bionys-568	99	2	the	the	DET
bionys-568	99	3	case	case	NOUN
bionys-568	99	4	of	of	ADP
bionys-568	99	5	11β	11β	NOUN
bionys-568	99	6	-	-	PUNCT
bionys-568	99	7	hsd1	hsd1	PROPN
bionys-568	99	8	rs12086634	rs12086634	PROPN
bionys-568	99	9	,	,	PUNCT
bionys-568	99	10	the	the	DET
bionys-568	99	11	gg	gg	PROPN
bionys-568	99	12	and	and	CCONJ
bionys-568	99	13	tg	tg	PROPN
bionys-568	99	14	genotypes	genotype	NOUN
bionys-568	99	15	were	be	AUX
bionys-568	99	16	more	more	ADV
bionys-568	99	17	prevalent	prevalent	ADJ
bionys-568	99	18	in	in	ADP
bionys-568	99	19	the	the	DET
bionys-568	99	20	hbv	hbv	NOUN
bionys-568	99	21	(	(	PUNCT
bionys-568	99	22	18	18	NUM
bionys-568	99	23	%	%	NOUN
bionys-568	99	24	and	and	CCONJ
bionys-568	99	25	72	72	NUM
bionys-568	99	26	%	%	NOUN
bionys-568	99	27	,	,	PUNCT
bionys-568	99	28	respectively	respectively	ADV
bionys-568	99	29	)	)	PUNCT
bionys-568	99	30	and	and	CCONJ
bionys-568	99	31	hcc	hcc	PROPN
bionys-568	99	32	patients	patient	NOUN
bionys-568	99	33	(	(	PUNCT
bionys-568	99	34	16	16	NUM
bionys-568	99	35	%	%	NOUN
bionys-568	99	36	and	and	CCONJ
bionys-568	99	37	80	80	NUM
bionys-568	99	38	%	%	NOUN
bionys-568	99	39	,	,	PUNCT
bionys-568	99	40	respectively	respectively	ADV
bionys-568	99	41	)	)	PUNCT
bionys-568	99	42	,	,	PUNCT
bionys-568	99	43	whereas	whereas	SCONJ
bionys-568	99	44	the	the	DET
bionys-568	99	45	control	control	NOUN
bionys-568	99	46	group	group	NOUN
bionys-568	99	47	exhibited	exhibit	VERB
bionys-568	99	48	the	the	DET
bionys-568	99	49	highest	high	ADJ
bionys-568	99	50	frequency	frequency	NOUN
bionys-568	99	51	of	of	ADP
bionys-568	99	52	the	the	DET
bionys-568	99	53	tt	tt	PROPN
bionys-568	99	54	genotype	genotype	NOUN
bionys-568	99	55	(	(	PUNCT
bionys-568	99	56	82	82	NUM
bionys-568	99	57	%	%	NOUN
bionys-568	99	58	,	,	PUNCT
bionys-568	99	59	p<0.001	p<0.001	PROPN
bionys-568	99	60	)	)	PUNCT
bionys-568	99	61	.	.	PUNCT
bionys-568	100	1	allelic	allelic	ADJ
bionys-568	100	2	distribution	distribution	NOUN
bionys-568	100	3	comparisons	comparison	NOUN
bionys-568	100	4	revealed	reveal	VERB
bionys-568	100	5	that	that	SCONJ
bionys-568	100	6	the	the	DET
bionys-568	100	7	g	g	PROPN
bionys-568	100	8	allele	allele	PROPN
bionys-568	100	9	was	be	AUX
bionys-568	100	10	significantly	significantly	ADV
bionys-568	100	11	more	more	ADV
bionys-568	100	12	frequent	frequent	ADJ
bionys-568	100	13	in	in	ADP
bionys-568	100	14	the	the	DET
bionys-568	100	15	hbv	hbv	NOUN
bionys-568	100	16	(	(	PUNCT
bionys-568	100	17	54	54	NUM
bionys-568	100	18	%	%	NOUN
bionys-568	100	19	)	)	PUNCT
bionys-568	100	20	and	and	CCONJ
bionys-568	100	21	hcc	hcc	PROPN
bionys-568	100	22	(	(	PUNCT
bionys-568	100	23	56	56	NUM
bionys-568	100	24	%	%	NOUN
bionys-568	100	25	)	)	PUNCT
bionys-568	100	26	groups	group	NOUN
bionys-568	100	27	compared	compare	VERB
bionys-568	100	28	to	to	ADP
bionys-568	100	29	the	the	DET
bionys-568	100	30	control	control	NOUN
bionys-568	100	31	group	group	NOUN
bionys-568	100	32	(	(	PUNCT
bionys-568	100	33	13	13	NUM
bionys-568	100	34	%	%	NOUN
bionys-568	100	35	,	,	PUNCT
bionys-568	100	36	p<0.001	p<0.001	PROPN
bionys-568	100	37	)	)	PUNCT
bionys-568	100	38	.	.	PUNCT
bionys-568	101	1	this	this	PRON
bionys-568	101	2	suggests	suggest	VERB
bionys-568	101	3	that	that	SCONJ
bionys-568	101	4	the	the	DET
bionys-568	101	5	g	g	PROPN
bionys-568	101	6	allele	allele	NOUN
bionys-568	101	7	may	may	AUX
bionys-568	101	8	contribute	contribute	VERB
bionys-568	101	9	to	to	ADP
bionys-568	101	10	an	an	DET
bionys-568	101	11	increased	increase	VERB
bionys-568	101	12	risk	risk	NOUN
bionys-568	101	13	of	of	ADP
bionys-568	101	14	both	both	DET
bionys-568	101	15	diseases	disease	NOUN
bionys-568	101	16	.	.	PUNCT
bionys-568	102	1	in	in	ADP
bionys-568	102	2	contrast	contrast	NOUN
bionys-568	102	3	,	,	PUNCT
bionys-568	102	4	the	the	DET
bionys-568	102	5	t	t	PROPN
bionys-568	102	6	allele	allele	NOUN
bionys-568	102	7	was	be	AUX
bionys-568	102	8	the	the	DET
bionys-568	102	9	most	most	ADV
bionys-568	102	10	common	common	ADJ
bionys-568	102	11	in	in	ADP
bionys-568	102	12	the	the	DET
bionys-568	102	13	control	control	NOUN
bionys-568	102	14	group	group	NOUN
bionys-568	102	15	(	(	PUNCT
bionys-568	102	16	87	87	NUM
bionys-568	102	17	%	%	NOUN
bionys-568	102	18	)	)	PUNCT
bionys-568	102	19	compared	compare	VERB
bionys-568	102	20	to	to	ADP
bionys-568	102	21	hbv	hbv	NOUN
bionys-568	102	22	(	(	PUNCT
bionys-568	102	23	46	46	NUM
bionys-568	102	24	%	%	NOUN
bionys-568	102	25	)	)	PUNCT
bionys-568	102	26	and	and	CCONJ
bionys-568	102	27	hcc	hcc	PROPN
bionys-568	102	28	(	(	PUNCT
bionys-568	102	29	44	44	NUM
bionys-568	102	30	%	%	NOUN
bionys-568	102	31	)	)	PUNCT
bionys-568	102	32	.	.	PUNCT
bionys-568	103	1	this	this	DET
bionys-568	103	2	allele	allele	NOUN
bionys-568	103	3	may	may	AUX
bionys-568	103	4	play	play	VERB
bionys-568	103	5	a	a	DET
bionys-568	103	6	protective	protective	ADJ
bionys-568	103	7	role	role	NOUN
bionys-568	103	8	against	against	ADP
bionys-568	103	9	disease	disease	NOUN
bionys-568	103	10	290	290	NUM
bionys-568	103	11	biologica	biologica	PROPN
bionys-568	103	12	nyssana	nyssana	PROPN
bionys-568	104	1	●	●	PUNCT
bionys-568	104	2	16	16	NUM
bionys-568	104	3	(	(	PUNCT
bionys-568	104	4	1	1	NUM
bionys-568	104	5	)	)	PUNCT
bionys-568	104	6	june	june	PROPN
bionys-568	104	7	2025	2025	NUM
bionys-568	104	8	:	:	PUNCT
bionys-568	104	9	287	287	NUM
bionys-568	104	10	-	-	SYM
bionys-568	104	11	296	296	NUM
bionys-568	104	12	al	al	PROPN
bionys-568	104	13	-	-	PUNCT
bionys-568	104	14	khaykanee	khaykanee	PROPN
bionys-568	104	15	et	et	PROPN
bionys-568	104	16	al	al	PROPN
bionys-568	104	17	.	.	PUNCT
bionys-568	105	1	●	●	PUNCT
bionys-568	105	2	role	role	NOUN
bionys-568	105	3	of	of	ADP
bionys-568	105	4	11β	11β	PROPN
bionys-568	105	5	-	-	PUNCT
bionys-568	105	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	105	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	105	8	gene	gene	NOUN
bionys-568	105	9	polymorphisms	polymorphism	NOUN
bionys-568	105	10	rs846910	rs846910	NOUN
bionys-568	105	11	and	and	CCONJ
bionys-568	105	12	rs12086634	rs12086634	PROPN
bionys-568	105	13	in	in	ADP
bionys-568	105	14	the	the	DET
bionys-568	105	15	etiology	etiology	NOUN
bionys-568	105	16	of	of	ADP
bionys-568	105	17	hepatocellular	hepatocellular	ADJ
bionys-568	105	18	carcinoma	carcinoma	NOUN
bionys-568	105	19	table	table	NOUN
bionys-568	105	20	1	1	NUM
bionys-568	105	21	.	.	PUNCT
bionys-568	105	22	demographic	demographic	ADJ
bionys-568	105	23	and	and	CCONJ
bionys-568	105	24	laboratory	laboratory	NOUN
bionys-568	105	25	data	datum	NOUN
bionys-568	105	26	for	for	ADP
bionys-568	105	27	the	the	DET
bionys-568	105	28	hbv	hbv	NOUN
bionys-568	105	29	,	,	PUNCT
bionys-568	105	30	hcc	hcc	PROPN
bionys-568	105	31	,	,	PUNCT
bionys-568	105	32	and	and	CCONJ
bionys-568	105	33	control	control	NOUN
bionys-568	105	34	groups	group	NOUN
bionys-568	105	35	variable	variable	ADJ
bionys-568	105	36	mean	mean	VERB
bionys-568	105	37	±	±	NUM
bionys-568	105	38	sd	sd	NOUN
bionys-568	105	39	.	.	PUNCT
bionys-568	106	1	hbv	hbv	PROPN
bionys-568	107	1	n=50	n=50	PROPN
bionys-568	107	2	hcc	hcc	PROPN
bionys-568	107	3	n=50	n=50	ADJ
bionys-568	107	4	control	control	NOUN
bionys-568	107	5	n=50	n=50	ADJ
bionys-568	107	6	p	p	ADJ
bionys-568	107	7	-	-	PUNCT
bionys-568	107	8	value	value	NOUN
bionys-568	107	9	gender	gender	NOUN
bionys-568	107	10	:	:	PUNCT
bionys-568	107	11	male	male	ADJ
bionys-568	107	12	n.	n.	NOUN
bionys-568	107	13	(	(	PUNCT
bionys-568	107	14	%	%	NOUN
bionys-568	107	15	)	)	PUNCT
bionys-568	107	16	22	22	NUM
bionys-568	107	17	(	(	PUNCT
bionys-568	107	18	46	46	NUM
bionys-568	107	19	)	)	SYM
bionys-568	107	20	18	18	NUM
bionys-568	107	21	(	(	PUNCT
bionys-568	107	22	42	42	NUM
bionys-568	107	23	)	)	PUNCT
bionys-568	107	24	25	25	NUM
bionys-568	107	25	(	(	PUNCT
bionys-568	107	26	64	64	NUM
bionys-568	107	27	)	)	PUNCT
bionys-568	107	28	0.325	0.325	NUM
bionys-568	107	29	female	female	ADJ
bionys-568	107	30	n.	n.	NOUN
bionys-568	107	31	(	(	PUNCT
bionys-568	107	32	%	%	NOUN
bionys-568	107	33	)	)	PUNCT
bionys-568	107	34	28	28	NUM
bionys-568	107	35	(	(	PUNCT
bionys-568	107	36	54	54	NUM
bionys-568	107	37	)	)	PUNCT
bionys-568	107	38	32	32	NUM
bionys-568	107	39	(	(	PUNCT
bionys-568	107	40	58	58	NUM
bionys-568	107	41	)	)	PUNCT
bionys-568	107	42	25	25	NUM
bionys-568	107	43	(	(	PUNCT
bionys-568	107	44	36	36	NUM
bionys-568	107	45	)	)	PUNCT
bionys-568	107	46	0.325	0.325	NUM
bionys-568	107	47	age	age	NOUN
bionys-568	107	48	(	(	PUNCT
bionys-568	107	49	years	year	NOUN
bionys-568	107	50	)	)	PUNCT
bionys-568	108	1	56.55±4.45	56.55±4.45	NUM
bionys-568	108	2	60.7±1.3	60.7±1.3	NUM
bionys-568	108	3	58.55±6.18	58.55±6.18	NUM
bionys-568	108	4	0.121	0.121	NUM
bionys-568	108	5	wbcs	wbc	NOUN
bionys-568	108	6	(	(	PUNCT
bionys-568	108	7	x	x	NOUN
bionys-568	108	8	103/µl	103/µl	NUM
bionys-568	108	9	)	)	PUNCT
bionys-568	108	10	6.11±2.87a	6.11±2.87a	NOUN
bionys-568	108	11	5.12±1.88a	5.12±1.88a	NUM
bionys-568	108	12	7.22±0.11	7.22±0.11	NOUN
bionys-568	108	13	<	<	NOUN
bionys-568	108	14	0.001	0.001	NUM
bionys-568	108	15	*	*	SYM
bionys-568	108	16	hb	hb	PROPN
bionys-568	108	17	(	(	PUNCT
bionys-568	108	18	gm	gm	PROPN
bionys-568	108	19	/	/	SYM
bionys-568	108	20	dl	dl	PROPN
bionys-568	108	21	)	)	PUNCT
bionys-568	108	22	9.45±1.43a	9.45±1.43a	NOUN
bionys-568	108	23	8.87±0.11a	8.87±0.11a	NUM
bionys-568	109	1	11.78±1.22	11.78±1.22	NUM
bionys-568	109	2	<	<	X
bionys-568	109	3	0.001	0.001	NUM
bionys-568	109	4	*	*	PUNCT
bionys-568	109	5	platelets	platelet	NOUN
bionys-568	109	6	(	(	PUNCT
bionys-568	109	7	x	x	NOUN
bionys-568	109	8	103/µl	103/µl	NUM
bionys-568	109	9	)	)	PUNCT
bionys-568	109	10	119.6±40.31a	119.6±40.31a	NUM
bionys-568	109	11	98.8±20.37a	98.8±20.37a	NUM
bionys-568	110	1	271.6±20.41	271.6±20.41	NUM
bionys-568	110	2	<	<	X
bionys-568	110	3	0.001	0.001	NUM
bionys-568	110	4	*	*	ADJ
bionys-568	110	5	p.c.v	p.c.v	X
bionys-568	110	6	(	(	PUNCT
bionys-568	110	7	%	%	INTJ
bionys-568	110	8	)	)	PUNCT
bionys-568	110	9	70.80±9.53a	70.80±9.53a	NUM
bionys-568	111	1	69.21±5.55a	69.21±5.55a	NUM
bionys-568	111	2	89.45±5.65	89.45±5.65	NUM
bionys-568	111	3	<	<	X
bionys-568	111	4	0.001	0.001	NUM
bionys-568	111	5	*	*	PUNCT
bionys-568	111	6	ast	ast	NOUN
bionys-568	111	7	(	(	PUNCT
bionys-568	111	8	iu	iu	PROPN
bionys-568	111	9	/	/	SYM
bionys-568	111	10	l	l	NOUN
bionys-568	111	11	)	)	PUNCT
bionys-568	111	12	43.86±12.15a	43.86±12.15a	NUM
bionys-568	111	13	103.7±18.31a	103.7±18.31a	NUM
bionys-568	111	14	17.4±4.66	17.4±4.66	NUM
bionys-568	111	15	<	<	X
bionys-568	111	16	0.001	0.001	NUM
bionys-568	111	17	*	*	PUNCT
bionys-568	111	18	alt(iu	alt(iu	ADP
bionys-568	111	19	/	/	SYM
bionys-568	111	20	l	l	NOUN
bionys-568	111	21	)	)	PUNCT
bionys-568	111	22	58.64±12.50a	58.64±12.50a	NUM
bionys-568	111	23	189.6±264.22a	189.6±264.22a	NUM
bionys-568	111	24	,	,	PUNCT
bionys-568	111	25	b	b	PROPN
bionys-568	111	26	13.11±6.58	13.11±6.58	NUM
bionys-568	111	27	<	<	NOUN
bionys-568	111	28	0.001	0.001	NUM
bionys-568	111	29	*	*	PUNCT
bionys-568	111	30	t.	t.	NOUN
bionys-568	111	31	bilirubin	bilirubin	NOUN
bionys-568	111	32	(	(	PUNCT
bionys-568	111	33	mg	mg	PROPN
bionys-568	111	34	/	/	SYM
bionys-568	111	35	dl	dl	NOUN
bionys-568	111	36	)	)	PUNCT
bionys-568	111	37	2.88±1.86a	2.88±1.86a	NUM
bionys-568	111	38	0.68±0.05a	0.68±0.05a	NUM
bionys-568	111	39	2.96±0.1	2.96±0.1	NUM
bionys-568	111	40	<	<	X
bionys-568	111	41	0.001	0.001	NUM
bionys-568	111	42	*	*	ADJ
bionys-568	111	43	albumin	albumin	NOUN
bionys-568	111	44	(	(	PUNCT
bionys-568	111	45	gm	gm	PROPN
bionys-568	111	46	/	/	SYM
bionys-568	111	47	dl	dl	PROPN
bionys-568	111	48	)	)	PUNCT
bionys-568	111	49	2.96±0.22a	2.96±0.22a	NUM
bionys-568	111	50	2.7±0.65a	2.7±0.65a	NOUN
bionys-568	111	51	,	,	PUNCT
bionys-568	111	52	b	b	PROPN
bionys-568	111	53	4.56±0.19	4.56±0.19	NUM
bionys-568	111	54	<	<	NOUN
bionys-568	111	55	0.001	0.001	NUM
bionys-568	111	56	*	*	PUNCT
bionys-568	111	57	t.	t.	NOUN
bionys-568	111	58	protein	protein	NOUN
bionys-568	111	59	(	(	PUNCT
bionys-568	111	60	gm	gm	PROPN
bionys-568	111	61	/	/	SYM
bionys-568	111	62	dl	dl	PROPN
bionys-568	111	63	)	)	PUNCT
bionys-568	111	64	7.33±1.02a	7.33±1.02a	NOUN
bionys-568	111	65	6.44±0.96a	6.44±0.96a	NUM
bionys-568	111	66	7.88±0.65	7.88±0.65	NOUN
bionys-568	111	67	<	<	NOUN
bionys-568	111	68	0.001	0.001	NUM
bionys-568	111	69	*	*	ADJ
bionys-568	111	70	alkaline	alkaline	NOUN
bionys-568	111	71	phosphatase	phosphatase	NOUN
bionys-568	111	72	(	(	PUNCT
bionys-568	111	73	iu	iu	PROPN
bionys-568	111	74	/	/	SYM
bionys-568	111	75	l	l	NOUN
bionys-568	111	76	)	)	PUNCT
bionys-568	111	77	68.06±44.82b	68.06±44.82b	NUM
bionys-568	111	78	130.5±57.32a	130.5±57.32a	NUM
bionys-568	111	79	67.14±11.40	67.14±11.40	NUM
bionys-568	111	80	<	<	X
bionys-568	111	81	0.001	0.001	NUM
bionys-568	111	82	*	*	ADJ
bionys-568	111	83	afp	afp	PROPN
bionys-568	111	84	(	(	PUNCT
bionys-568	111	85	ng	ng	PROPN
bionys-568	111	86	/	/	SYM
bionys-568	111	87	ml	ml	NOUN
bionys-568	111	88	)	)	PUNCT
bionys-568	111	89	11.24±2.60	11.24±2.60	NUM
bionys-568	111	90	28.27±20.64a	28.27±20.64a	NOUN
bionys-568	111	91	<	<	X
bionys-568	111	92	0.001	0.001	NUM
bionys-568	111	93	*	*	ADJ
bionys-568	111	94	viral	viral	ADJ
bionys-568	111	95	load	load	NOUN
bionys-568	111	96	(	(	PUNCT
bionys-568	111	97	iu	iu	ADP
bionys-568	111	98	)	)	PUNCT
bionys-568	111	99	698.96.9±1067.4	698.96.9±1067.4	NUM
bionys-568	112	1	7435.21±1153.6a	7435.21±1153.6a	NUM
bionys-568	112	2	<	<	NOUN
bionys-568	112	3	0.001	0.001	NUM
bionys-568	112	4	*	*	PUNCT
bionys-568	112	5	*	*	PUNCT
bionys-568	112	6	statistically	statistically	ADV
bionys-568	112	7	significant	significant	ADJ
bionys-568	112	8	at	at	ADP
bionys-568	112	9	p≤0.05	p≤0.05	NOUN
bionys-568	112	10	,	,	PUNCT
bionys-568	112	11	a	a	PRON
bionys-568	112	12	significantly	significantly	ADV
bionys-568	112	13	differs	differ	VERB
bionys-568	112	14	from	from	ADP
bionys-568	112	15	control	control	PROPN
bionys-568	112	16	group	group	NOUN
bionys-568	112	17	,	,	PUNCT
bionys-568	112	18	b	b	PROPN
bionys-568	112	19	significantly	significantly	ADV
bionys-568	112	20	differs	differ	VERB
bionys-568	112	21	from	from	ADP
bionys-568	112	22	hbv	hbv	PROPN
bionys-568	112	23	group	group	NOUN
bionys-568	112	24	table	table	NOUN
bionys-568	112	25	2	2	NUM
bionys-568	112	26	.	.	PUNCT
bionys-568	113	1	the	the	DET
bionys-568	113	2	distribution	distribution	NOUN
bionys-568	113	3	of	of	ADP
bionys-568	113	4	genotypes	genotype	NOUN
bionys-568	113	5	and	and	CCONJ
bionys-568	113	6	alleles	allele	NOUN
bionys-568	113	7	for	for	ADP
bionys-568	113	8	the	the	DET
bionys-568	113	9	11β	11β	NOUN
bionys-568	113	10	-	-	PUNCT
bionys-568	113	11	hsd1	hsd1	ADJ
bionys-568	113	12	rs846910	rs846910	NOUN
bionys-568	113	13	and	and	CCONJ
bionys-568	113	14	rs12086634	rs12086634	PROPN
bionys-568	113	15	gene	gene	NOUN
bionys-568	113	16	polymorphisms	polymorphism	NOUN
bionys-568	113	17	among	among	ADP
bionys-568	113	18	the	the	DET
bionys-568	113	19	hbv	hbv	NOUN
bionys-568	113	20	,	,	PUNCT
bionys-568	113	21	hcc	hcc	PROPN
bionys-568	113	22	,	,	PUNCT
bionys-568	113	23	and	and	CCONJ
bionys-568	113	24	control	control	NOUN
bionys-568	113	25	groups	group	NOUN
bionys-568	113	26	hbv	hbv	NOUN
bionys-568	113	27	(	(	PUNCT
bionys-568	113	28	n=50	n=50	ADJ
bionys-568	113	29	)	)	PUNCT
bionys-568	113	30	hcc	hcc	PROPN
bionys-568	113	31	(	(	PUNCT
bionys-568	113	32	n=50	n=50	ADJ
bionys-568	113	33	)	)	PUNCT
bionys-568	113	34	control	control	NOUN
bionys-568	113	35	(	(	PUNCT
bionys-568	113	36	n=50	n=50	ADJ
bionys-568	113	37	)	)	PUNCT
bionys-568	113	38	χ2	χ2	PROPN
bionys-568	113	39	p	p	NOUN
bionys-568	114	1	no	no	INTJ
bionys-568	114	2	.	.	PUNCT
bionys-568	115	1	%	%	INTJ
bionys-568	115	2	no	no	INTJ
bionys-568	115	3	.	.	PUNCT
bionys-568	116	1	%	%	INTJ
bionys-568	116	2	no	no	INTJ
bionys-568	116	3	.	.	PUNCT
bionys-568	117	1	%	%	INTJ
bionys-568	118	1	rs12086634	rs12086634	PROPN
bionys-568	118	2	gg	gg	NOUN
bionys-568	118	3	9	9	NUM
bionys-568	118	4	18	18	NUM
bionys-568	118	5	%	%	NOUN
bionys-568	118	6	8	8	NUM
bionys-568	118	7	(	(	PUNCT
bionys-568	118	8	16	16	NUM
bionys-568	118	9	%	%	NOUN
bionys-568	118	10	)	)	PUNCT
bionys-568	118	11	4	4	NUM
bionys-568	118	12	(	(	PUNCT
bionys-568	118	13	8	8	NUM
bionys-568	118	14	%	%	NOUN
bionys-568	118	15	)	)	PUNCT
bionys-568	119	1	50.47	50.47	NUM
bionys-568	119	2	*	*	PUNCT
bionys-568	120	1	<	<	X
bionys-568	120	2	0.001*tg	0.001*tg	NUM
bionys-568	120	3	36	36	NUM
bionys-568	120	4	72	72	NUM
bionys-568	120	5	%	%	NOUN
bionys-568	120	6	40	40	NUM
bionys-568	120	7	(	(	PUNCT
bionys-568	120	8	80	80	NUM
bionys-568	120	9	%	%	NOUN
bionys-568	120	10	)	)	PUNCT
bionys-568	120	11	5	5	NUM
bionys-568	120	12	(	(	PUNCT
bionys-568	120	13	10	10	NUM
bionys-568	120	14	%	%	NOUN
bionys-568	120	15	)	)	PUNCT
bionys-568	120	16	tt	tt	PROPN
bionys-568	120	17	5	5	NUM
bionys-568	120	18	(	(	PUNCT
bionys-568	120	19	10	10	NUM
bionys-568	120	20	%	%	NOUN
bionys-568	120	21	2	2	NUM
bionys-568	120	22	(	(	PUNCT
bionys-568	120	23	4	4	NUM
bionys-568	120	24	%	%	NOUN
bionys-568	120	25	)	)	PUNCT
bionys-568	120	26	41	41	NUM
bionys-568	120	27	(	(	PUNCT
bionys-568	120	28	82	82	NUM
bionys-568	120	29	%	%	NOUN
bionys-568	120	30	)	)	PUNCT
bionys-568	120	31	allele	allele	NOUN
bionys-568	120	32	g	g	ADP
bionys-568	120	33	54	54	NUM
bionys-568	120	34	(	(	PUNCT
bionys-568	120	35	54	54	NUM
bionys-568	120	36	%	%	NOUN
bionys-568	120	37	)	)	PUNCT
bionys-568	120	38	56	56	NUM
bionys-568	120	39	(	(	PUNCT
bionys-568	120	40	56	56	NUM
bionys-568	120	41	%	%	NOUN
bionys-568	120	42	)	)	PUNCT
bionys-568	120	43	13	13	NUM
bionys-568	120	44	(	(	PUNCT
bionys-568	120	45	13	13	NUM
bionys-568	120	46	%	%	NOUN
bionys-568	120	47	)	)	PUNCT
bionys-568	121	1	46.83	46.83	NUM
bionys-568	121	2	*	*	PUNCT
bionys-568	122	1	<	<	X
bionys-568	122	2	0.001	0.001	NUM
bionys-568	122	3	*	*	SYM
bionys-568	122	4	t	t	PROPN
bionys-568	122	5	46	46	NUM
bionys-568	122	6	(	(	PUNCT
bionys-568	122	7	46	46	NUM
bionys-568	122	8	%	%	NOUN
bionys-568	122	9	)	)	PUNCT
bionys-568	122	10	44	44	NUM
bionys-568	122	11	(	(	PUNCT
bionys-568	122	12	44	44	NUM
bionys-568	122	13	%	%	NOUN
bionys-568	122	14	)	)	PUNCT
bionys-568	122	15	87	87	NUM
bionys-568	122	16	(	(	PUNCT
bionys-568	122	17	87	87	NUM
bionys-568	122	18	%	%	NOUN
bionys-568	122	19	)	)	PUNCT
bionys-568	123	1	rs846910	rs846910	NOUN
bionys-568	123	2	aa	aa	NOUN
bionys-568	123	3	24	24	NUM
bionys-568	123	4	(	(	PUNCT
bionys-568	123	5	48	48	NUM
bionys-568	123	6	%	%	NOUN
bionys-568	123	7	)	)	PUNCT
bionys-568	123	8	22	22	NUM
bionys-568	123	9	(	(	PUNCT
bionys-568	123	10	44	44	NUM
bionys-568	123	11	%	%	NOUN
bionys-568	123	12	)	)	PUNCT
bionys-568	123	13	46	46	NUM
bionys-568	123	14	(	(	PUNCT
bionys-568	123	15	92	92	NUM
bionys-568	123	16	%	%	NOUN
bionys-568	123	17	)	)	PUNCT
bionys-568	124	1	71.51	71.51	NUM
bionys-568	124	2	*	*	PUNCT
bionys-568	125	1	<	<	X
bionys-568	125	2	0.001	0.001	NUM
bionys-568	125	3	*	*	SYM
bionys-568	125	4	ag	ag	PROPN
bionys-568	125	5	26	26	NUM
bionys-568	125	6	(	(	PUNCT
bionys-568	125	7	52	52	NUM
bionys-568	125	8	%	%	NOUN
bionys-568	125	9	)	)	PUNCT
bionys-568	125	10	28	28	NUM
bionys-568	125	11	(	(	PUNCT
bionys-568	125	12	56	56	NUM
bionys-568	125	13	%	%	NOUN
bionys-568	125	14	)	)	PUNCT
bionys-568	125	15	4	4	NUM
bionys-568	125	16	(	(	PUNCT
bionys-568	125	17	8	8	NUM
bionys-568	125	18	%	%	NOUN
bionys-568	125	19	)	)	PUNCT
bionys-568	125	20	allele	allele	NOUN
bionys-568	125	21	g	g	ADP
bionys-568	125	22	26	26	NUM
bionys-568	125	23	(	(	PUNCT
bionys-568	125	24	26	26	NUM
bionys-568	125	25	%	%	NOUN
bionys-568	125	26	)	)	PUNCT
bionys-568	125	27	28	28	NUM
bionys-568	125	28	(	(	PUNCT
bionys-568	125	29	28	28	NUM
bionys-568	125	30	%	%	NOUN
bionys-568	125	31	)	)	PUNCT
bionys-568	125	32	96	96	NUM
bionys-568	126	1	(	(	PUNCT
bionys-568	126	2	96	96	NUM
bionys-568	126	3	%	%	NOUN
bionys-568	126	4	)	)	PUNCT
bionys-568	127	1	65.264	65.264	NUM
bionys-568	127	2	*	*	PUNCT
bionys-568	127	3	<	<	X
bionys-568	127	4	0.001	0.001	NUM
bionys-568	127	5	*	*	PUNCT
bionys-568	127	6	a	a	DET
bionys-568	127	7	74	74	NUM
bionys-568	127	8	(	(	PUNCT
bionys-568	127	9	74	74	NUM
bionys-568	127	10	%	%	NOUN
bionys-568	127	11	)	)	PUNCT
bionys-568	127	12	72	72	NUM
bionys-568	127	13	(	(	PUNCT
bionys-568	127	14	72	72	NUM
bionys-568	127	15	%	%	NOUN
bionys-568	127	16	)	)	PUNCT
bionys-568	127	17	4	4	NUM
bionys-568	127	18	(	(	PUNCT
bionys-568	127	19	4	4	NUM
bionys-568	127	20	%	%	NOUN
bionys-568	127	21	)	)	PUNCT
bionys-568	127	22	*	*	PUNCT
bionys-568	127	23	statistically	statistically	ADV
bionys-568	127	24	significant	significant	ADJ
bionys-568	127	25	at	at	ADP
bionys-568	127	26	p≤0.05	p≤0.05	ADP
bionys-568	127	27	291	291	NUM
bionys-568	127	28	biologica	biologica	PROPN
bionys-568	127	29	nyssana	nyssana	PROPN
bionys-568	127	30	●	●	PUNCT
bionys-568	127	31	16	16	NUM
bionys-568	127	32	(	(	PUNCT
bionys-568	127	33	1	1	NUM
bionys-568	127	34	)	)	PUNCT
bionys-568	127	35	june	june	PROPN
bionys-568	127	36	2025	2025	NUM
bionys-568	127	37	:	:	PUNCT
bionys-568	127	38	287	287	NUM
bionys-568	127	39	-	-	SYM
bionys-568	127	40	296	296	NUM
bionys-568	127	41	al	al	PROPN
bionys-568	127	42	-	-	PUNCT
bionys-568	127	43	khaykanee	khaykanee	PROPN
bionys-568	127	44	et	et	PROPN
bionys-568	127	45	al	al	PROPN
bionys-568	127	46	.	.	PUNCT
bionys-568	128	1	●	●	PUNCT
bionys-568	128	2	role	role	NOUN
bionys-568	128	3	of	of	ADP
bionys-568	128	4	11β	11β	PROPN
bionys-568	128	5	-	-	PUNCT
bionys-568	128	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	128	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	128	8	gene	gene	NOUN
bionys-568	128	9	polymorphisms	polymorphism	NOUN
bionys-568	128	10	rs846910	rs846910	NOUN
bionys-568	128	11	and	and	CCONJ
bionys-568	128	12	rs12086634	rs12086634	PROPN
bionys-568	128	13	in	in	ADP
bionys-568	128	14	the	the	DET
bionys-568	128	15	etiology	etiology	NOUN
bionys-568	128	16	of	of	ADP
bionys-568	128	17	hepatocellular	hepatocellular	ADJ
bionys-568	128	18	carcinoma	carcinoma	NOUN
bionys-568	128	19	progression	progression	NOUN
bionys-568	128	20	.	.	PUNCT
bionys-568	129	1	the	the	DET
bionys-568	129	2	genotype	genotype	NOUN
bionys-568	129	3	distribution	distribution	NOUN
bionys-568	129	4	of	of	ADP
bionys-568	129	5	the	the	DET
bionys-568	129	6	11β	11β	NOUN
bionys-568	129	7	-	-	PUNCT
bionys-568	129	8	hsd1	hsd1	ADJ
bionys-568	129	9	rs846910	rs846910	NOUN
bionys-568	129	10	polymorphism	polymorphism	NOUN
bionys-568	129	11	also	also	ADV
bionys-568	129	12	showed	show	VERB
bionys-568	129	13	a	a	DET
bionys-568	129	14	clear	clear	ADJ
bionys-568	129	15	difference	difference	NOUN
bionys-568	129	16	between	between	ADP
bionys-568	129	17	the	the	DET
bionys-568	129	18	three	three	NUM
bionys-568	129	19	studied	studied	ADJ
bionys-568	129	20	groups	group	NOUN
bionys-568	129	21	,	,	PUNCT
bionys-568	129	22	with	with	ADP
bionys-568	129	23	the	the	DET
bionys-568	129	24	aa	aa	PROPN
bionys-568	129	25	genotype	genotype	NOUN
bionys-568	129	26	being	be	AUX
bionys-568	129	27	the	the	DET
bionys-568	129	28	most	most	ADV
bionys-568	129	29	common	common	ADJ
bionys-568	129	30	in	in	ADP
bionys-568	129	31	the	the	DET
bionys-568	129	32	control	control	NOUN
bionys-568	129	33	group	group	NOUN
bionys-568	129	34	(	(	PUNCT
bionys-568	129	35	92	92	NUM
bionys-568	129	36	%	%	NOUN
bionys-568	129	37	)	)	PUNCT
bionys-568	129	38	,	,	PUNCT
bionys-568	129	39	hbv	hbv	NOUN
bionys-568	129	40	(	(	PUNCT
bionys-568	129	41	48	48	NUM
bionys-568	129	42	%	%	NOUN
bionys-568	129	43	)	)	PUNCT
bionys-568	129	44	,	,	PUNCT
bionys-568	129	45	and	and	CCONJ
bionys-568	129	46	hcc	hcc	PROPN
bionys-568	129	47	(	(	PUNCT
bionys-568	129	48	44	44	NUM
bionys-568	129	49	%	%	NOUN
bionys-568	129	50	)	)	PUNCT
bionys-568	129	51	.	.	PUNCT
bionys-568	130	1	the	the	DET
bionys-568	130	2	ag	ag	PROPN
bionys-568	130	3	genotype	genotype	NOUN
bionys-568	130	4	was	be	AUX
bionys-568	130	5	the	the	DET
bionys-568	130	6	most	most	ADV
bionys-568	130	7	common	common	ADJ
bionys-568	130	8	in	in	ADP
bionys-568	130	9	the	the	DET
bionys-568	130	10	hcc	hcc	PROPN
bionys-568	130	11	group	group	NOUN
bionys-568	130	12	(	(	PUNCT
bionys-568	130	13	56	56	NUM
bionys-568	130	14	%	%	NOUN
bionys-568	130	15	)	)	PUNCT
bionys-568	130	16	,	,	PUNCT
bionys-568	130	17	less	less	ADV
bionys-568	130	18	common	common	ADJ
bionys-568	130	19	in	in	ADP
bionys-568	130	20	the	the	DET
bionys-568	130	21	hbv	hbv	NOUN
bionys-568	130	22	(	(	PUNCT
bionys-568	130	23	52	52	NUM
bionys-568	130	24	%	%	NOUN
bionys-568	130	25	)	)	PUNCT
bionys-568	130	26	,	,	PUNCT
bionys-568	130	27	and	and	CCONJ
bionys-568	130	28	very	very	ADV
bionys-568	130	29	rare	rare	ADJ
bionys-568	130	30	in	in	ADP
bionys-568	130	31	the	the	DET
bionys-568	130	32	control	control	NOUN
bionys-568	130	33	group	group	NOUN
bionys-568	130	34	(	(	PUNCT
bionys-568	130	35	8	8	NUM
bionys-568	130	36	%	%	NOUN
bionys-568	130	37	)	)	PUNCT
bionys-568	130	38	.	.	PUNCT
bionys-568	131	1	the	the	DET
bionys-568	131	2	results	result	NOUN
bionys-568	131	3	indicate	indicate	VERB
bionys-568	131	4	that	that	SCONJ
bionys-568	131	5	the	the	DET
bionys-568	131	6	distribution	distribution	NOUN
bionys-568	131	7	of	of	ADP
bionys-568	131	8	the	the	DET
bionys-568	131	9	a	a	DET
bionys-568	131	10	allele	allele	NOUN
bionys-568	131	11	may	may	AUX
bionys-568	131	12	be	be	AUX
bionys-568	131	13	associated	associate	VERB
bionys-568	131	14	with	with	ADP
bionys-568	131	15	the	the	DET
bionys-568	131	16	risk	risk	NOUN
bionys-568	131	17	of	of	ADP
bionys-568	131	18	infection	infection	NOUN
bionys-568	131	19	with	with	ADP
bionys-568	131	20	hepatitis	hepatitis	PROPN
bionys-568	131	21	b	b	PROPN
bionys-568	131	22	virus	virus	NOUN
bionys-568	131	23	and	and	CCONJ
bionys-568	131	24	hepatocellular	hepatocellular	ADJ
bionys-568	131	25	carcinoma	carcinoma	NOUN
bionys-568	131	26	,	,	PUNCT
bionys-568	131	27	and	and	CCONJ
bionys-568	131	28	the	the	DET
bionys-568	131	29	exact	exact	ADJ
bionys-568	131	30	opposite	opposite	NOUN
bionys-568	131	31	for	for	ADP
bionys-568	131	32	the	the	DET
bionys-568	131	33	g	g	PROPN
bionys-568	131	34	allele	allele	NOUN
bionys-568	131	35	,	,	PUNCT
bionys-568	131	36	as	as	SCONJ
bionys-568	131	37	it	it	PRON
bionys-568	131	38	was	be	AUX
bionys-568	131	39	more	more	ADV
bionys-568	131	40	widespread	widespread	ADJ
bionys-568	131	41	and	and	CCONJ
bionys-568	131	42	distributed	distribute	VERB
bionys-568	131	43	in	in	ADP
bionys-568	131	44	the	the	DET
bionys-568	131	45	control	control	NOUN
bionys-568	131	46	group	group	NOUN
bionys-568	131	47	(	(	PUNCT
bionys-568	131	48	96	96	NUM
bionys-568	131	49	%	%	NOUN
bionys-568	131	50	)	)	PUNCT
bionys-568	131	51	compared	compare	VERB
bionys-568	131	52	to	to	ADP
bionys-568	131	53	its	its	PRON
bionys-568	131	54	prevalence	prevalence	NOUN
bionys-568	131	55	in	in	ADP
bionys-568	131	56	the	the	DET
bionys-568	131	57	liver	liver	NOUN
bionys-568	131	58	cancer	cancer	NOUN
bionys-568	131	59	group	group	NOUN
bionys-568	131	60	(	(	PUNCT
bionys-568	131	61	28	28	NUM
bionys-568	131	62	%	%	NOUN
bionys-568	131	63	)	)	PUNCT
bionys-568	131	64	and	and	CCONJ
bionys-568	131	65	in	in	ADP
bionys-568	131	66	the	the	DET
bionys-568	131	67	hepatitis	hepatitis	PROPN
bionys-568	131	68	b	b	PROPN
bionys-568	131	69	virus	virus	NOUN
bionys-568	131	70	group	group	NOUN
bionys-568	131	71	(	(	PUNCT
bionys-568	131	72	26	26	NUM
bionys-568	131	73	%	%	NOUN
bionys-568	131	74	)	)	PUNCT
bionys-568	131	75	,	,	PUNCT
bionys-568	131	76	so	so	CCONJ
bionys-568	131	77	it	it	PRON
bionys-568	131	78	is	be	AUX
bionys-568	131	79	considered	consider	VERB
bionys-568	131	80	a	a	DET
bionys-568	131	81	protective	protective	ADJ
bionys-568	131	82	factor	factor	NOUN
bionys-568	131	83	.	.	PUNCT
bionys-568	132	1	these	these	DET
bionys-568	132	2	distributions	distribution	NOUN
bionys-568	132	3	of	of	ADP
bionys-568	132	4	the	the	DET
bionys-568	132	5	genetic	genetic	ADJ
bionys-568	132	6	patterns	pattern	NOUN
bionys-568	132	7	in	in	ADP
bionys-568	132	8	both	both	DET
bionys-568	132	9	rs12086634r	rs12086634r	NOUN
bionys-568	132	10	and	and	CCONJ
bionys-568	132	11	rs846910	rs846910	NOUN
bionys-568	132	12	indicate	indicate	VERB
bionys-568	132	13	that	that	SCONJ
bionys-568	132	14	they	they	PRON
bionys-568	132	15	may	may	AUX
bionys-568	132	16	have	have	VERB
bionys-568	132	17	an	an	DET
bionys-568	132	18	important	important	ADJ
bionys-568	132	19	role	role	NOUN
bionys-568	132	20	in	in	ADP
bionys-568	132	21	the	the	DET
bionys-568	132	22	genetic	genetic	ADJ
bionys-568	132	23	predisposition	predisposition	NOUN
bionys-568	132	24	to	to	ADP
bionys-568	132	25	infection	infection	NOUN
bionys-568	132	26	with	with	ADP
bionys-568	132	27	the	the	DET
bionys-568	132	28	hepatitis	hepatitis	PROPN
bionys-568	132	29	b	b	PROPN
bionys-568	132	30	virus	virus	NOUN
bionys-568	132	31	and	and	CCONJ
bionys-568	132	32	its	its	PRON
bionys-568	132	33	development	development	NOUN
bionys-568	132	34	into	into	ADP
bionys-568	132	35	hepatocellular	hepatocellular	ADJ
bionys-568	132	36	carcinoma	carcinoma	NOUN
bionys-568	132	37	.	.	PUNCT
bionys-568	133	1	the	the	DET
bionys-568	133	2	overrepresentation	overrepresentation	NOUN
bionys-568	133	3	of	of	ADP
bionys-568	133	4	specific	specific	ADJ
bionys-568	133	5	alleles	allele	NOUN
bionys-568	133	6	in	in	ADP
bionys-568	133	7	the	the	DET
bionys-568	133	8	disease	disease	NOUN
bionys-568	133	9	groups	group	NOUN
bionys-568	133	10	highlights	highlight	VERB
bionys-568	133	11	their	their	PRON
bionys-568	133	12	potential	potential	NOUN
bionys-568	133	13	as	as	ADP
bionys-568	133	14	genetic	genetic	ADJ
bionys-568	133	15	markers	marker	NOUN
bionys-568	133	16	for	for	ADP
bionys-568	133	17	susceptibility	susceptibility	NOUN
bionys-568	133	18	or	or	CCONJ
bionys-568	133	19	protection	protection	NOUN
bionys-568	133	20	.	.	PUNCT
bionys-568	134	1	the	the	DET
bionys-568	134	2	findings	finding	NOUN
bionys-568	134	3	provide	provide	VERB
bionys-568	134	4	evidence	evidence	NOUN
bionys-568	134	5	of	of	ADP
bionys-568	134	6	significant	significant	ADJ
bionys-568	134	7	associations	association	NOUN
bionys-568	134	8	between	between	ADP
bionys-568	134	9	the	the	DET
bionys-568	134	10	rs12086634	rs12086634	PROPN
bionys-568	134	11	and	and	CCONJ
bionys-568	134	12	rs846910	rs846910	NOUN
bionys-568	134	13	polymorphisms	polymorphism	NOUN
bionys-568	134	14	and	and	CCONJ
bionys-568	134	15	hbv	hbv	NOUN
bionys-568	134	16	and	and	CCONJ
bionys-568	134	17	hcc	hcc	PROPN
bionys-568	134	18	.	.	PUNCT
bionys-568	135	1	the	the	DET
bionys-568	135	2	g	g	PROPN
bionys-568	135	3	allele	allele	NOUN
bionys-568	135	4	in	in	ADP
bionys-568	135	5	rs12086634	rs12086634	PROPN
bionys-568	135	6	and	and	CCONJ
bionys-568	135	7	the	the	DET
bionys-568	135	8	a	a	DET
bionys-568	135	9	allele	allele	NOUN
bionys-568	135	10	in	in	ADP
bionys-568	135	11	rs846910	rs846910	NOUN
bionys-568	135	12	appear	appear	VERB
bionys-568	135	13	to	to	PART
bionys-568	135	14	be	be	AUX
bionys-568	135	15	risk	risk	NOUN
bionys-568	135	16	factors	factor	NOUN
bionys-568	135	17	,	,	PUNCT
bionys-568	135	18	while	while	SCONJ
bionys-568	135	19	the	the	DET
bionys-568	135	20	t	t	PROPN
bionys-568	135	21	allele	allele	NOUN
bionys-568	135	22	in	in	ADP
bionys-568	135	23	rs12086634	rs12086634	PROPN
bionys-568	135	24	and	and	CCONJ
bionys-568	135	25	the	the	DET
bionys-568	135	26	g	g	PROPN
bionys-568	135	27	allele	allele	NOUN
bionys-568	135	28	in	in	ADP
bionys-568	135	29	rs846910	rs846910	NOUN
bionys-568	135	30	might	might	AUX
bionys-568	135	31	have	have	VERB
bionys-568	135	32	protective	protective	ADJ
bionys-568	135	33	effects	effect	NOUN
bionys-568	135	34	.	.	PUNCT
bionys-568	136	1	additionally	additionally	ADV
bionys-568	136	2	,	,	PUNCT
bionys-568	136	3	we	we	PRON
bionys-568	136	4	analyzed	analyze	VERB
bionys-568	136	5	the	the	DET
bionys-568	136	6	association	association	NOUN
bionys-568	136	7	of	of	ADP
bionys-568	136	8	11β	11β	PROPN
bionys-568	136	9	-	-	PUNCT
bionys-568	136	10	hsd1	hsd1	ADJ
bionys-568	136	11	rs846910	rs846910	NOUN
bionys-568	136	12	and	and	CCONJ
bionys-568	136	13	rs12086634	rs12086634	ADJ
bionys-568	136	14	polymorphisms	polymorphism	NOUN
bionys-568	136	15	across	across	ADP
bionys-568	136	16	the	the	DET
bionys-568	136	17	three	three	NUM
bionys-568	136	18	groups	group	NOUN
bionys-568	136	19	by	by	ADP
bionys-568	136	20	comparison	comparison	NOUN
bionys-568	136	21	of	of	ADP
bionys-568	136	22	their	their	PRON
bionys-568	136	23	genotypic	genotypic	ADJ
bionys-568	136	24	frequencies	frequency	NOUN
bionys-568	136	25	.	.	PUNCT
bionys-568	137	1	this	this	PRON
bionys-568	137	2	provided	provide	VERB
bionys-568	137	3	a	a	DET
bionys-568	137	4	valuable	valuable	ADJ
bionys-568	137	5	insight	insight	NOUN
bionys-568	137	6	into	into	ADP
bionys-568	137	7	the	the	DET
bionys-568	137	8	potential	potential	ADJ
bionys-568	137	9	influence	influence	NOUN
bionys-568	137	10	of	of	ADP
bionys-568	137	11	these	these	DET
bionys-568	137	12	polymorphisms	polymorphism	NOUN
bionys-568	137	13	on	on	ADP
bionys-568	137	14	the	the	DET
bionys-568	137	15	risk	risk	NOUN
bionys-568	137	16	of	of	ADP
bionys-568	137	17	hcc	hcc	PROPN
bionys-568	137	18	and	and	CCONJ
bionys-568	137	19	hbv	hbv	NOUN
bionys-568	137	20	infection	infection	NOUN
bionys-568	137	21	.	.	PUNCT
bionys-568	138	1	regarding	regard	VERB
bionys-568	138	2	the	the	DET
bionys-568	138	3	rs12086634	rs12086634	PROPN
bionys-568	138	4	polymorphism	polymorphism	NOUN
bionys-568	138	5	,	,	PUNCT
bionys-568	138	6	the	the	DET
bionys-568	138	7	analysis	analysis	NOUN
bionys-568	138	8	revealed	reveal	VERB
bionys-568	138	9	significant	significant	ADJ
bionys-568	138	10	differences	difference	NOUN
bionys-568	138	11	in	in	ADP
bionys-568	138	12	the	the	DET
bionys-568	138	13	genotypic	genotypic	NOUN
bionys-568	138	14	distributions	distribution	NOUN
bionys-568	138	15	between	between	ADP
bionys-568	138	16	the	the	DET
bionys-568	138	17	groups	group	NOUN
bionys-568	138	18	.	.	PUNCT
bionys-568	139	1	by	by	ADP
bionys-568	139	2	comparing	compare	VERB
bionys-568	139	3	hepatitis	hepatitis	PROPN
bionys-568	139	4	b	b	PROPN
bionys-568	139	5	virus	virus	NOUN
bionys-568	139	6	(	(	PUNCT
bionys-568	139	7	hbv	hbv	NOUN
bionys-568	139	8	)	)	PUNCT
bionys-568	139	9	with	with	ADP
bionys-568	139	10	hepatocellular	hepatocellular	ADJ
bionys-568	139	11	carcinoma	carcinoma	NOUN
bionys-568	139	12	(	(	PUNCT
bionys-568	139	13	hcc	hcc	PROPN
bionys-568	139	14	)	)	PUNCT
bionys-568	139	15	,	,	PUNCT
bionys-568	139	16	the	the	DET
bionys-568	139	17	tg	tg	PROPN
bionys-568	139	18	genotype	genotype	NOUN
bionys-568	139	19	showed	show	VERB
bionys-568	139	20	a	a	DET
bionys-568	139	21	strong	strong	ADJ
bionys-568	139	22	association	association	NOUN
bionys-568	139	23	(	(	PUNCT
bionys-568	139	24	or=25.11	or=25.11	ADJ
bionys-568	139	25	,	,	PUNCT
bionys-568	139	26	p<0.001	p<0.001	PROPN
bionys-568	139	27	)	)	PUNCT
bionys-568	139	28	,	,	PUNCT
bionys-568	139	29	indicating	indicate	VERB
bionys-568	139	30	an	an	DET
bionys-568	139	31	increased	increased	ADJ
bionys-568	139	32	risk	risk	NOUN
bionys-568	139	33	of	of	ADP
bionys-568	139	34	hcc	hcc	PROPN
bionys-568	139	35	in	in	ADP
bionys-568	139	36	individuals	individual	NOUN
bionys-568	139	37	carrying	carry	VERB
bionys-568	139	38	the	the	DET
bionys-568	139	39	tg	tg	PROPN
bionys-568	139	40	genotype	genotype	NOUN
bionys-568	139	41	for	for	ADP
bionys-568	139	42	rs12086634	rs12086634	PROPN
bionys-568	139	43	.	.	PUNCT
bionys-568	140	1	additionally	additionally	ADV
bionys-568	140	2	,	,	PUNCT
bionys-568	140	3	the	the	DET
bionys-568	140	4	tt	tt	PROPN
bionys-568	140	5	genotype	genotype	NOUN
bionys-568	140	6	also	also	ADV
bionys-568	140	7	showed	show	VERB
bionys-568	140	8	a	a	DET
bionys-568	140	9	significant	significant	ADJ
bionys-568	140	10	association	association	NOUN
bionys-568	140	11	with	with	ADP
bionys-568	140	12	both	both	CCONJ
bionys-568	140	13	the	the	DET
bionys-568	140	14	hcc	hcc	PROPN
bionys-568	140	15	subset	subset	NOUN
bionys-568	140	16	compared	compare	VERB
bionys-568	140	17	to	to	ADP
bionys-568	140	18	the	the	DET
bionys-568	140	19	control	control	NOUN
bionys-568	140	20	group	group	NOUN
bionys-568	140	21	(	(	PUNCT
bionys-568	140	22	or=0.009	or=0.009	NOUN
bionys-568	140	23	,	,	PUNCT
bionys-568	140	24	p=0.0133	p=0.0133	PROPN
bionys-568	140	25	)	)	PUNCT
bionys-568	140	26	and	and	CCONJ
bionys-568	140	27	hbv	hbv	NOUN
bionys-568	140	28	versus	versus	ADP
bionys-568	140	29	the	the	DET
bionys-568	140	30	control	control	NOUN
bionys-568	140	31	group	group	NOUN
bionys-568	140	32	(	(	PUNCT
bionys-568	140	33	or=0.024	or=0.024	PROPN
bionys-568	140	34	,	,	PUNCT
bionys-568	140	35	p<0.001	p<0.001	PROPN
bionys-568	140	36	)	)	PUNCT
bionys-568	140	37	.	.	PUNCT
bionys-568	141	1	this	this	PRON
bionys-568	141	2	suggests	suggest	VERB
bionys-568	141	3	that	that	SCONJ
bionys-568	141	4	the	the	DET
bionys-568	141	5	tt	tt	PROPN
bionys-568	141	6	genotype	genotype	NOUN
bionys-568	141	7	is	be	AUX
bionys-568	141	8	a	a	DET
bionys-568	141	9	protective	protective	ADJ
bionys-568	141	10	factor	factor	NOUN
bionys-568	141	11	against	against	ADP
bionys-568	141	12	hbv	hbv	NOUN
bionys-568	141	13	and	and	CCONJ
bionys-568	141	14	hcc	hcc	PROPN
bionys-568	141	15	for	for	ADP
bionys-568	141	16	rs12086634	rs12086634	PROPN
bionys-568	141	17	.	.	PUNCT
bionys-568	142	1	significant	significant	ADJ
bionys-568	142	2	results	result	NOUN
bionys-568	142	3	emerged	emerge	VERB
bionys-568	142	4	,	,	PUNCT
bionys-568	142	5	as	as	SCONJ
bionys-568	142	6	the	the	DET
bionys-568	142	7	t	t	PROPN
bionys-568	142	8	allele	allele	NOUN
bionys-568	142	9	consistently	consistently	ADV
bionys-568	142	10	showed	show	VERB
bionys-568	142	11	a	a	DET
bionys-568	142	12	lower	low	ADJ
bionys-568	142	13	odds	odd	NOUN
bionys-568	142	14	ratio	ratio	NOUN
bionys-568	142	15	compared	compare	VERB
bionys-568	142	16	to	to	ADP
bionys-568	142	17	the	the	DET
bionys-568	142	18	g	g	PROPN
bionys-568	142	19	allele	allele	NOUN
bionys-568	142	20	in	in	ADP
bionys-568	142	21	all	all	DET
bionys-568	142	22	groups	group	NOUN
bionys-568	142	23	studied	study	VERB
bionys-568	142	24	.	.	PUNCT
bionys-568	143	1	therefore	therefore	ADV
bionys-568	143	2	,	,	PUNCT
bionys-568	143	3	the	the	DET
bionys-568	143	4	t	t	PROPN
bionys-568	143	5	allele	allele	NOUN
bionys-568	143	6	for	for	ADP
bionys-568	143	7	rs12086634	rs12086634	PROPN
bionys-568	143	8	is	be	AUX
bionys-568	143	9	considered	consider	VERB
bionys-568	143	10	to	to	PART
bionys-568	143	11	reduce	reduce	VERB
bionys-568	143	12	the	the	DET
bionys-568	143	13	risk	risk	NOUN
bionys-568	143	14	of	of	ADP
bionys-568	143	15	hepatocellular	hepatocellular	ADJ
bionys-568	143	16	carcinoma	carcinoma	NOUN
bionys-568	143	17	and	and	CCONJ
bionys-568	143	18	hepatitis	hepatitis	PROPN
bionys-568	143	19	b	b	PROPN
bionys-568	143	20	virus	virus	NOUN
bionys-568	143	21	infection	infection	NOUN
bionys-568	143	22	.	.	PUNCT
bionys-568	144	1	the	the	DET
bionys-568	144	2	gg	gg	NOUN
bionys-568	144	3	genotype	genotype	NOUN
bionys-568	144	4	of	of	ADP
bionys-568	144	5	the	the	DET
bionys-568	144	6	rs846910	rs846910	NOUN
bionys-568	144	7	polymorphism	polymorphism	NOUN
bionys-568	144	8	showed	show	VERB
bionys-568	144	9	a	a	DET
bionys-568	144	10	significant	significant	ADJ
bionys-568	144	11	association	association	NOUN
bionys-568	144	12	with	with	ADP
bionys-568	144	13	a	a	DET
bionys-568	144	14	low	low	ADJ
bionys-568	144	15	odds	odd	NOUN
bionys-568	144	16	ratio	ratio	NOUN
bionys-568	144	17	(	(	PUNCT
bionys-568	144	18	or=0.045	or=0.045	NOUN
bionys-568	144	19	,	,	PUNCT
bionys-568	144	20	p<0.001	p<0.001	PROPN
bionys-568	144	21	)	)	PUNCT
bionys-568	144	22	when	when	SCONJ
bionys-568	144	23	comparing	compare	VERB
bionys-568	144	24	the	the	DET
bionys-568	144	25	hepatocellular	hepatocellular	ADJ
bionys-568	144	26	carcinoma	carcinoma	NOUN
bionys-568	144	27	group	group	NOUN
bionys-568	144	28	with	with	ADP
bionys-568	144	29	the	the	DET
bionys-568	144	30	hepatitis	hepatitis	PROPN
bionys-568	144	31	b	b	PROPN
bionys-568	144	32	virus	virus	NOUN
bionys-568	144	33	group	group	NOUN
bionys-568	144	34	.	.	PUNCT
bionys-568	145	1	this	this	PRON
bionys-568	145	2	indicates	indicate	VERB
bionys-568	145	3	that	that	SCONJ
bionys-568	145	4	it	it	PRON
bionys-568	145	5	is	be	AUX
bionys-568	145	6	a	a	DET
bionys-568	145	7	protective	protective	ADJ
bionys-568	145	8	factor	factor	NOUN
bionys-568	145	9	against	against	ADP
bionys-568	145	10	hepatocellular	hepatocellular	ADJ
bionys-568	145	11	carcinoma	carcinoma	NOUN
bionys-568	145	12	in	in	ADP
bionys-568	145	13	individuals	individual	NOUN
bionys-568	145	14	carrying	carry	VERB
bionys-568	145	15	this	this	DET
bionys-568	145	16	genotype	genotype	NOUN
bionys-568	145	17	.	.	PUNCT
bionys-568	146	1	in	in	ADP
bionys-568	146	2	contrast	contrast	NOUN
bionys-568	146	3	,	,	PUNCT
bionys-568	146	4	the	the	DET
bionys-568	146	5	ga	ga	PROPN
bionys-568	146	6	genotype	genotype	NOUN
bionys-568	146	7	was	be	AUX
bionys-568	146	8	a	a	DET
bionys-568	146	9	risk	risk	NOUN
bionys-568	146	10	factor	factor	NOUN
bionys-568	146	11	for	for	ADP
bionys-568	146	12	hepatocellular	hepatocellular	ADJ
bionys-568	146	13	carcinoma	carcinoma	NOUN
bionys-568	146	14	compared	compare	VERB
bionys-568	146	15	to	to	ADP
bionys-568	146	16	the	the	DET
bionys-568	146	17	hepatitis	hepatitis	PROPN
bionys-568	146	18	b	b	PROPN
bionys-568	146	19	virus	virus	NOUN
bionys-568	146	20	(	(	PUNCT
bionys-568	146	21	or=21.77	or=21.77	ADJ
bionys-568	146	22	,	,	PUNCT
bionys-568	146	23	p<0.001	p<0.001	ADJ
bionys-568	146	24	)	)	PUNCT
bionys-568	146	25	and	and	CCONJ
bionys-568	146	26	control	control	NOUN
bionys-568	146	27	groups	group	NOUN
bionys-568	146	28	(	(	PUNCT
bionys-568	146	29	or=19.11	or=19.11	ADJ
bionys-568	146	30	,	,	PUNCT
bionys-568	146	31	p<0.001	p<0.001	PROPN
bionys-568	146	32	)	)	PUNCT
bionys-568	146	33	,	,	PUNCT
bionys-568	146	34	representing	represent	VERB
bionys-568	146	35	a	a	DET
bionys-568	146	36	risk	risk	NOUN
bionys-568	146	37	factor	factor	NOUN
bionys-568	146	38	for	for	ADP
bionys-568	146	39	hepatocellular	hepatocellular	ADJ
bionys-568	146	40	carcinoma	carcinoma	NOUN
bionys-568	146	41	.	.	PUNCT
bionys-568	147	1	in	in	ADP
bionys-568	147	2	the	the	DET
bionys-568	147	3	comparison	comparison	NOUN
bionys-568	147	4	between	between	ADP
bionys-568	147	5	hbv	hbv	NOUN
bionys-568	147	6	and	and	CCONJ
bionys-568	147	7	control	control	NOUN
bionys-568	147	8	,	,	PUNCT
bionys-568	147	9	the	the	DET
bionys-568	147	10	ga	ga	PROPN
bionys-568	147	11	genotype	genotype	NOUN
bionys-568	147	12	was	be	AUX
bionys-568	147	13	associated	associate	VERB
bionys-568	147	14	with	with	ADP
bionys-568	147	15	a	a	DET
bionys-568	147	16	very	very	ADV
bionys-568	147	17	high	high	ADJ
bionys-568	147	18	odds	odd	NOUN
bionys-568	147	19	ratio	ratio	NOUN
bionys-568	147	20	(	(	PUNCT
bionys-568	147	21	or=40.77	or=40.77	ADJ
bionys-568	147	22	,	,	PUNCT
bionys-568	147	23	p<0.001	p<0.001	PROPN
bionys-568	147	24	)	)	PUNCT
bionys-568	147	25	,	,	PUNCT
bionys-568	147	26	suggesting	suggest	VERB
bionys-568	147	27	a	a	DET
bionys-568	147	28	strong	strong	ADJ
bionys-568	147	29	correlation	correlation	NOUN
bionys-568	147	30	with	with	ADP
bionys-568	147	31	hbv	hbv	NOUN
bionys-568	147	32	infection	infection	NOUN
bionys-568	147	33	risk	risk	NOUN
bionys-568	147	34	.	.	PUNCT
bionys-568	148	1	the	the	DET
bionys-568	148	2	a	a	DET
bionys-568	148	3	allele	allele	NOUN
bionys-568	148	4	was	be	AUX
bionys-568	148	5	consistently	consistently	ADV
bionys-568	148	6	associated	associate	VERB
bionys-568	148	7	with	with	ADP
bionys-568	148	8	higher	high	ADJ
bionys-568	148	9	odds	odd	NOUN
bionys-568	148	10	of	of	ADP
bionys-568	148	11	both	both	DET
bionys-568	148	12	hbv	hbv	NOUN
bionys-568	148	13	and	and	CCONJ
bionys-568	148	14	hcc	hcc	PROPN
bionys-568	148	15	,	,	PUNCT
bionys-568	148	16	with	with	ADP
bionys-568	148	17	g	g	PROPN
bionys-568	148	18	allele	allele	NOUN
bionys-568	148	19	showing	show	VERB
bionys-568	148	20	a	a	DET
bionys-568	148	21	protective	protective	ADJ
bionys-568	148	22	role	role	NOUN
bionys-568	148	23	.	.	PUNCT
bionys-568	149	1	the	the	DET
bionys-568	149	2	p	p	NOUN
bionys-568	149	3	-	-	PUNCT
bionys-568	149	4	values	value	NOUN
bionys-568	149	5	for	for	ADP
bionys-568	149	6	the	the	DET
bionys-568	149	7	majority	majority	NOUN
bionys-568	149	8	of	of	ADP
bionys-568	149	9	comparisons	comparison	NOUN
bionys-568	149	10	between	between	ADP
bionys-568	149	11	the	the	DET
bionys-568	149	12	groups	group	NOUN
bionys-568	149	13	were	be	AUX
bionys-568	149	14	statistically	statistically	ADV
bionys-568	149	15	significant	significant	ADJ
bionys-568	149	16	,	,	PUNCT
bionys-568	149	17	particularly	particularly	ADV
bionys-568	149	18	for	for	ADP
bionys-568	149	19	the	the	DET
bionys-568	149	20	tg	tg	PROPN
bionys-568	149	21	and	and	CCONJ
bionys-568	149	22	ga	ga	PROPN
bionys-568	149	23	genotypes	genotype	NOUN
bionys-568	149	24	,	,	PUNCT
bionys-568	149	25	indicating	indicate	VERB
bionys-568	149	26	a	a	DET
bionys-568	149	27	strong	strong	ADJ
bionys-568	149	28	association	association	NOUN
bionys-568	149	29	between	between	ADP
bionys-568	149	30	these	these	DET
bionys-568	149	31	genotypes	genotype	NOUN
bionys-568	149	32	and	and	CCONJ
bionys-568	149	33	the	the	DET
bionys-568	149	34	presence	presence	NOUN
bionys-568	149	35	of	of	ADP
bionys-568	149	36	liver	liver	NOUN
bionys-568	149	37	disease	disease	NOUN
bionys-568	149	38	.	.	PUNCT
bionys-568	150	1	the	the	DET
bionys-568	150	2	distribution	distribution	NOUN
bionys-568	150	3	of	of	ADP
bionys-568	150	4	observed	observed	ADJ
bionys-568	150	5	and	and	CCONJ
bionys-568	150	6	expected	expect	VERB
bionys-568	150	7	genotypic	genotypic	ADJ
bionys-568	150	8	frequencies	frequency	NOUN
bionys-568	150	9	for	for	ADP
bionys-568	150	10	rs12086634	rs12086634	PROPN
bionys-568	150	11	and	and	CCONJ
bionys-568	150	12	rs846910	rs846910	PROPN
bionys-568	150	13	polymorphisms	polymorphism	NOUN
bionys-568	150	14	was	be	AUX
bionys-568	150	15	also	also	ADV
bionys-568	150	16	analyzed	analyze	VERB
bionys-568	150	17	across	across	ADP
bionys-568	150	18	the	the	DET
bionys-568	150	19	three	three	NUM
bionys-568	150	20	groups	group	NOUN
bionys-568	150	21	(	(	PUNCT
bionys-568	150	22	tab	tab	NOUN
bionys-568	150	23	.	.	PUNCT
bionys-568	150	24	4	4	NUM
bionys-568	150	25	)	)	PUNCT
bionys-568	150	26	.	.	PUNCT
bionys-568	151	1	the	the	DET
bionys-568	151	2	chi	chi	ADJ
bionys-568	151	3	-	-	PUNCT
bionys-568	151	4	square	square	ADJ
bionys-568	151	5	test	test	NOUN
bionys-568	151	6	(	(	PUNCT
bionys-568	151	7	χ2	χ2	PROPN
bionys-568	151	8	)	)	PUNCT
bionys-568	151	9	and	and	CCONJ
bionys-568	151	10	p	p	NOUN
bionys-568	151	11	-	-	PUNCT
bionys-568	151	12	values	value	NOUN
bionys-568	151	13	were	be	AUX
bionys-568	151	14	used	use	VERB
bionys-568	151	15	to	to	PART
bionys-568	151	16	assess	assess	VERB
bionys-568	151	17	deviations	deviation	NOUN
bionys-568	151	18	from	from	ADP
bionys-568	151	19	hardy	hardy	ADJ
bionys-568	151	20	-	-	PUNCT
bionys-568	151	21	weinberg	weinberg	NOUN
bionys-568	151	22	equilibrium	equilibrium	NOUN
bionys-568	151	23	(	(	PUNCT
bionys-568	151	24	hwe	hwe	PROPN
bionys-568	151	25	)	)	PUNCT
bionys-568	151	26	within	within	ADP
bionys-568	151	27	these	these	DET
bionys-568	151	28	groups	group	NOUN
bionys-568	151	29	.	.	PUNCT
bionys-568	152	1	in	in	ADP
bionys-568	152	2	the	the	DET
bionys-568	152	3	caase	caase	NOUN
bionys-568	152	4	of	of	ADP
bionys-568	152	5	rs12086634	rs12086634	PROPN
bionys-568	152	6	,	,	PUNCT
bionys-568	152	7	the	the	DET
bionys-568	152	8	observed	observed	ADJ
bionys-568	152	9	frequencies	frequency	NOUN
bionys-568	152	10	of	of	ADP
bionys-568	152	11	the	the	DET
bionys-568	152	12	gg	gg	NOUN
bionys-568	152	13	,	,	PUNCT
bionys-568	152	14	tg	tg	PROPN
bionys-568	152	15	,	,	PUNCT
bionys-568	152	16	and	and	CCONJ
bionys-568	152	17	tt	tt	PROPN
bionys-568	152	18	genotypes	genotype	NOUN
bionys-568	152	19	in	in	ADP
bionys-568	152	20	the	the	DET
bionys-568	152	21	hcc	hcc	PROPN
bionys-568	152	22	group	group	NOUN
bionys-568	152	23	showed	show	VERB
bionys-568	152	24	a	a	DET
bionys-568	152	25	significant	significant	ADJ
bionys-568	152	26	deviation	deviation	NOUN
bionys-568	152	27	from	from	ADP
bionys-568	152	28	the	the	DET
bionys-568	152	29	expected	expect	VERB
bionys-568	152	30	frequencies	frequency	NOUN
bionys-568	152	31	(	(	PUNCT
bionys-568	152	32	χ2=0.271	χ2=0.271	NOUN
bionys-568	152	33	,	,	PUNCT
bionys-568	152	34	p=0.018	p=0.018	NOUN
bionys-568	152	35	)	)	PUNCT
bionys-568	152	36	,	,	PUNCT
bionys-568	152	37	indicating	indicate	VERB
bionys-568	152	38	disequilibrium	disequilibrium	NOUN
bionys-568	152	39	,	,	PUNCT
bionys-568	152	40	reinforcing	reinforce	VERB
bionys-568	152	41	the	the	DET
bionys-568	152	42	hypothesis	hypothesis	NOUN
bionys-568	152	43	that	that	PRON
bionys-568	152	44	the	the	DET
bionys-568	152	45	rs12086634	rs12086634	PROPN
bionys-568	152	46	polymorphism	polymorphism	NOUN
bionys-568	152	47	may	may	AUX
bionys-568	152	48	play	play	VERB
bionys-568	152	49	a	a	DET
bionys-568	152	50	role	role	NOUN
bionys-568	152	51	in	in	ADP
bionys-568	152	52	liver	liver	NOUN
bionys-568	152	53	cancer	cancer	NOUN
bionys-568	152	54	susceptibility	susceptibility	NOUN
bionys-568	152	55	.	.	PUNCT
bionys-568	153	1	conversely	conversely	ADV
bionys-568	153	2	,	,	PUNCT
bionys-568	153	3	the	the	DET
bionys-568	153	4	hbv	hbv	NOUN
bionys-568	153	5	and	and	CCONJ
bionys-568	153	6	control	control	NOUN
bionys-568	153	7	groups	group	NOUN
bionys-568	153	8	showed	show	VERB
bionys-568	153	9	no	no	DET
bionys-568	153	10	significant	significant	ADJ
bionys-568	153	11	deviations	deviation	NOUN
bionys-568	153	12	(	(	PUNCT
bionys-568	153	13	χ2=1.69	χ2=1.69	NOUN
bionys-568	153	14	,	,	PUNCT
bionys-568	153	15	p=0.184	p=0.184	NOUN
bionys-568	153	16	;	;	PUNCT
bionys-568	153	17	χ2=3.87	χ2=3.87	NUM
bionys-568	153	18	,	,	PUNCT
bionys-568	153	19	p=0.325	p=0.325	NOUN
bionys-568	153	20	for	for	ADP
bionys-568	153	21	the	the	DET
bionys-568	153	22	hbv	hbv	NOUN
bionys-568	153	23	and	and	CCONJ
bionys-568	153	24	control	control	NOUN
bionys-568	153	25	groups	group	NOUN
bionys-568	153	26	,	,	PUNCT
bionys-568	153	27	respectively	respectively	ADV
bionys-568	153	28	)	)	PUNCT
bionys-568	153	29	,	,	PUNCT
bionys-568	153	30	indicating	indicate	VERB
bionys-568	153	31	that	that	SCONJ
bionys-568	153	32	the	the	DET
bionys-568	153	33	distribution	distribution	NOUN
bionys-568	153	34	of	of	ADP
bionys-568	153	35	rs12086634	rs12086634	ADJ
bionys-568	153	36	genotypes	genotype	NOUN
bionys-568	153	37	in	in	ADP
bionys-568	153	38	both	both	CCONJ
bionys-568	153	39	healthy	healthy	ADJ
bionys-568	153	40	individuals	individual	NOUN
bionys-568	153	41	and	and	CCONJ
bionys-568	153	42	the	the	DET
bionys-568	153	43	hbv	hbv	NOUN
bionys-568	153	44	group	group	NOUN
bionys-568	153	45	follows	follow	VERB
bionys-568	153	46	the	the	DET
bionys-568	153	47	expected	expect	VERB
bionys-568	153	48	patterns	pattern	NOUN
bionys-568	153	49	(	(	PUNCT
bionys-568	153	50	tab	tab	NOUN
bionys-568	153	51	.	.	PUNCT
bionys-568	153	52	4	4	NUM
bionys-568	153	53	)	)	PUNCT
bionys-568	153	54	.	.	PUNCT
bionys-568	154	1	for	for	ADP
bionys-568	154	2	rs846910	rs846910	NOUN
bionys-568	154	3	,	,	PUNCT
bionys-568	154	4	the	the	DET
bionys-568	154	5	hcc	hcc	PROPN
bionys-568	154	6	group	group	NOUN
bionys-568	154	7	showed	show	VERB
bionys-568	154	8	a	a	DET
bionys-568	154	9	significant	significant	ADJ
bionys-568	154	10	deviation	deviation	NOUN
bionys-568	154	11	from	from	ADP
bionys-568	154	12	hwe	hwe	PROPN
bionys-568	154	13	(	(	PUNCT
bionys-568	154	14	χ2=0.214	χ2=0.214	NUM
bionys-568	154	15	,	,	PUNCT
bionys-568	154	16	p=0.015	p=0.015	NOUN
bionys-568	154	17	)	)	PUNCT
bionys-568	154	18	,	,	PUNCT
bionys-568	154	19	mainly	mainly	ADV
bionys-568	154	20	due	due	ADP
bionys-568	154	21	to	to	ADP
bionys-568	154	22	an	an	DET
bionys-568	154	23	overrepresentation	overrepresentation	NOUN
bionys-568	154	24	of	of	ADP
bionys-568	154	25	the	the	DET
bionys-568	154	26	ga	ga	PROPN
bionys-568	154	27	genotype	genotype	NOUN
bionys-568	154	28	compared	compare	VERB
bionys-568	154	29	to	to	ADP
bionys-568	154	30	the	the	DET
bionys-568	154	31	expected	expect	VERB
bionys-568	154	32	frequencies	frequency	NOUN
bionys-568	154	33	(	(	PUNCT
bionys-568	154	34	28	28	NUM
bionys-568	154	35	vs.	vs.	ADP
bionys-568	154	36	9.4	9.4	NUM
bionys-568	154	37	,	,	PUNCT
bionys-568	154	38	tab	tab	NOUN
bionys-568	154	39	.	.	NOUN
bionys-568	154	40	4	4	NUM
bionys-568	154	41	)	)	PUNCT
bionys-568	154	42	.	.	PUNCT
bionys-568	155	1	this	this	PRON
bionys-568	155	2	suggests	suggest	VERB
bionys-568	155	3	a	a	DET
bionys-568	155	4	potential	potential	ADJ
bionys-568	155	5	association	association	NOUN
bionys-568	155	6	between	between	ADP
bionys-568	155	7	the	the	DET
bionys-568	155	8	ga	ga	PROPN
bionys-568	155	9	genotype	genotype	NOUN
bionys-568	155	10	and	and	CCONJ
bionys-568	155	11	increased	increase	VERB
bionys-568	155	12	hcc	hcc	PROPN
bionys-568	155	13	susceptibility	susceptibility	NOUN
bionys-568	155	14	.	.	PUNCT
bionys-568	156	1	in	in	ADP
bionys-568	156	2	contrast	contrast	NOUN
bionys-568	156	3	,	,	PUNCT
bionys-568	156	4	the	the	DET
bionys-568	156	5	hbv	hbv	NOUN
bionys-568	156	6	and	and	CCONJ
bionys-568	156	7	control	control	NOUN
bionys-568	156	8	groups	group	NOUN
bionys-568	156	9	did	do	AUX
bionys-568	156	10	not	not	PART
bionys-568	156	11	show	show	VERB
bionys-568	156	12	a	a	DET
bionys-568	156	13	significant	significant	ADJ
bionys-568	156	14	deviation	deviation	NOUN
bionys-568	156	15	(	(	PUNCT
bionys-568	156	16	χ2=4.22	χ2=4.22	NOUN
bionys-568	156	17	,	,	PUNCT
bionys-568	156	18	p=0.251	p=0.251	PROPN
bionys-568	156	19	,	,	PUNCT
bionys-568	156	20	χ2=6.32	χ2=6.32	PROPN
bionys-568	156	21	,	,	PUNCT
bionys-568	156	22	p=0.536	p=0.536	VERB
bionys-568	156	23	for	for	ADP
bionys-568	156	24	the	the	DET
bionys-568	156	25	hbv	hbv	NOUN
bionys-568	156	26	and	and	CCONJ
bionys-568	156	27	control	control	NOUN
bionys-568	156	28	groups	group	NOUN
bionys-568	156	29	,	,	PUNCT
bionys-568	156	30	respectively	respectively	ADV
bionys-568	156	31	)	)	PUNCT
bionys-568	156	32	,	,	PUNCT
bionys-568	156	33	suggesting	suggest	VERB
bionys-568	156	34	that	that	SCONJ
bionys-568	156	35	rs846910	rs846910	NOUN
bionys-568	156	36	may	may	AUX
bionys-568	156	37	not	not	PART
bionys-568	156	38	play	play	VERB
bionys-568	156	39	a	a	DET
bionys-568	156	40	major	major	ADJ
bionys-568	156	41	role	role	NOUN
bionys-568	156	42	in	in	ADP
bionys-568	156	43	hbv	hbv	NOUN
bionys-568	156	44	susceptibility	susceptibility	NOUN
bionys-568	156	45	in	in	ADP
bionys-568	156	46	the	the	DET
bionys-568	156	47	control	control	NOUN
bionys-568	156	48	group	group	NOUN
bionys-568	156	49	.	.	PUNCT
bionys-568	157	1	the	the	DET
bionys-568	157	2	significant	significant	ADJ
bionys-568	157	3	deviations	deviation	NOUN
bionys-568	157	4	from	from	ADP
bionys-568	157	5	hwe	hwe	PROPN
bionys-568	157	6	observed	observe	VERB
bionys-568	157	7	in	in	ADP
bionys-568	157	8	the	the	DET
bionys-568	157	9	hcc	hcc	PROPN
bionys-568	157	10	group	group	NOUN
bionys-568	157	11	for	for	ADP
bionys-568	157	12	both	both	DET
bionys-568	157	13	polymorphisms	polymorphism	NOUN
bionys-568	157	14	suggest	suggest	VERB
bionys-568	157	15	that	that	SCONJ
bionys-568	157	16	rs12086634	rs12086634	PROPN
bionys-568	157	17	and	and	CCONJ
bionys-568	157	18	rs846910	rs846910	NOUN
bionys-568	157	19	may	may	AUX
bionys-568	157	20	influence	influence	VERB
bionys-568	157	21	susceptibility	susceptibility	NOUN
bionys-568	157	22	to	to	ADP
bionys-568	157	23	hcc	hcc	PROPN
bionys-568	157	24	,	,	PUNCT
bionys-568	157	25	potentially	potentially	ADV
bionys-568	157	26	through	through	ADP
bionys-568	157	27	their	their	PRON
bionys-568	157	28	292	292	NUM
bionys-568	157	29	biologica	biologica	PROPN
bionys-568	157	30	nyssana	nyssana	PROPN
bionys-568	158	1	●	●	PUNCT
bionys-568	158	2	16	16	NUM
bionys-568	158	3	(	(	PUNCT
bionys-568	158	4	1	1	NUM
bionys-568	158	5	)	)	PUNCT
bionys-568	158	6	june	june	PROPN
bionys-568	158	7	2025	2025	NUM
bionys-568	158	8	:	:	PUNCT
bionys-568	158	9	287	287	NUM
bionys-568	158	10	-	-	SYM
bionys-568	158	11	296	296	NUM
bionys-568	158	12	al	al	PROPN
bionys-568	158	13	-	-	PUNCT
bionys-568	158	14	khaykanee	khaykanee	PROPN
bionys-568	158	15	et	et	PROPN
bionys-568	158	16	al	al	PROPN
bionys-568	158	17	.	.	PUNCT
bionys-568	159	1	●	●	PUNCT
bionys-568	159	2	role	role	NOUN
bionys-568	159	3	of	of	ADP
bionys-568	159	4	11β	11β	PROPN
bionys-568	159	5	-	-	PUNCT
bionys-568	159	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	159	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	159	8	gene	gene	NOUN
bionys-568	159	9	polymorphisms	polymorphism	NOUN
bionys-568	159	10	rs846910	rs846910	NOUN
bionys-568	159	11	and	and	CCONJ
bionys-568	159	12	rs12086634	rs12086634	PROPN
bionys-568	159	13	in	in	ADP
bionys-568	159	14	the	the	DET
bionys-568	159	15	etiology	etiology	NOUN
bionys-568	159	16	of	of	ADP
bionys-568	159	17	hepatocellular	hepatocellular	ADJ
bionys-568	159	18	carcinoma	carcinoma	NOUN
bionys-568	159	19	table	table	NOUN
bionys-568	159	20	3	3	NUM
bionys-568	159	21	.	.	PUNCT
bionys-568	159	22	genotypic	genotypic	ADJ
bionys-568	159	23	frequencies	frequency	NOUN
bionys-568	159	24	and	and	CCONJ
bionys-568	159	25	associations	association	NOUN
bionys-568	159	26	of	of	ADP
bionys-568	159	27	11β	11β	NOUN
bionys-568	159	28	-	-	PUNCT
bionys-568	159	29	hsd1	hsd1	ADJ
bionys-568	159	30	rs846910	rs846910	NOUN
bionys-568	159	31	and	and	CCONJ
bionys-568	159	32	rs12086634	rs12086634	PROPN
bionys-568	159	33	in	in	ADP
bionys-568	159	34	hbv	hbv	PROPN
bionys-568	159	35	,	,	PUNCT
bionys-568	159	36	hcc	hcc	PROPN
bionys-568	159	37	,	,	PUNCT
bionys-568	159	38	and	and	CCONJ
bionys-568	159	39	control	control	NOUN
bionys-568	159	40	groups	group	NOUN
bionys-568	159	41	p1	p1	PROPN
bionys-568	159	42	or1	or1	PROPN
bionys-568	159	43	(	(	PUNCT
bionys-568	159	44	ci	ci	PROPN
bionys-568	159	45	.	.	PROPN
bionys-568	159	46	95	95	NUM
bionys-568	159	47	%	%	NOUN
bionys-568	159	48	)	)	PUNCT
bionys-568	159	49	p2	p2	PROPN
bionys-568	159	50	or2	or2	X
bionys-568	159	51	(	(	PUNCT
bionys-568	159	52	ci	ci	NOUN
bionys-568	159	53	.	.	PROPN
bionys-568	159	54	95	95	NUM
bionys-568	159	55	%	%	NOUN
bionys-568	159	56	)	)	PUNCT
bionys-568	159	57	p3	p3	PROPN
bionys-568	159	58	or3	or3	PROPN
bionys-568	159	59	(	(	PUNCT
bionys-568	159	60	ci	ci	PROPN
bionys-568	159	61	.	.	PROPN
bionys-568	159	62	95	95	NUM
bionys-568	159	63	%	%	NOUN
bionys-568	159	64	)	)	PUNCT
bionys-568	159	65	rs12086634	rs12086634	PROPN
bionys-568	159	66	genotype	genotype	NOUN
bionys-568	159	67	gg	gg	PROPN
bionys-568	159	68	0.42	0.42	NUM
bionys-568	159	69	0.69	0.69	NUM
bionys-568	159	70	(	(	PUNCT
bionys-568	159	71	0.26	0.26	NUM
bionys-568	159	72	-	-	SYM
bionys-568	159	73	1.83	1.83	NUM
bionys-568	159	74	)	)	PUNCT
bionys-568	159	75	0.036	0.036	NUM
bionys-568	159	76	3.63	3.63	NUM
bionys-568	159	77	(	(	PUNCT
bionys-568	159	78	1.082	1.082	NUM
bionys-568	159	79	-	-	SYM
bionys-568	159	80	12.18	12.18	NUM
bionys-568	159	81	)	)	PUNCT
bionys-568	159	82	0.14	0.14	NUM
bionys-568	159	83	2.52	2.52	NUM
bionys-568	159	84	(	(	PUNCT
bionys-568	159	85	0.722	0.722	NUM
bionys-568	159	86	-	-	SYM
bionys-568	159	87	8.81	8.81	NUM
bionys-568	159	88	)	)	PUNCT
bionys-568	159	89	tg	tg	ADP
bionys-568	159	90	<	<	X
bionys-568	159	91	0.001	0.001	NUM
bionys-568	159	92	25.11	25.11	NUM
bionys-568	159	93	(	(	PUNCT
bionys-568	159	94	8.36	8.36	NUM
bionys-568	159	95	-	-	SYM
bionys-568	159	96	71.22	71.22	NUM
bionys-568	159	97	)	)	PUNCT
bionys-568	159	98	<	<	X
bionys-568	159	99	0.001	0.001	NUM
bionys-568	159	100	*	*	SYM
bionys-568	159	101	23.14	23.14	NUM
bionys-568	159	102	(	(	PUNCT
bionys-568	159	103	7.61	7.61	NUM
bionys-568	159	104	-	-	SYM
bionys-568	159	105	70.30	70.30	NUM
bionys-568	159	106	)	)	PUNCT
bionys-568	159	107	<	<	X
bionys-568	159	108	0.001	0.001	NUM
bionys-568	159	109	*	*	SYM
bionys-568	159	110	23.14	23.14	NUM
bionys-568	159	111	(	(	PUNCT
bionys-568	159	112	7.61	7.61	NUM
bionys-568	159	113	-	-	SYM
bionys-568	159	114	70.30	70.30	NUM
bionys-568	159	115	)	)	PUNCT
bionys-568	159	116	tt	tt	PROPN
bionys-568	159	117	<	<	X
bionys-568	159	118	0.001	0.001	NUM
bionys-568	159	119	*	*	SYM
bionys-568	159	120	0.03	0.03	NUM
bionys-568	159	121	(	(	PUNCT
bionys-568	159	122	0.002	0.002	NUM
bionys-568	159	123	-	-	PUNCT
bionys-568	159	124	0.087	0.087	NUM
bionys-568	159	125	)	)	PUNCT
bionys-568	159	126	0.0133	0.0133	NUM
bionys-568	159	127	*	*	NOUN
bionys-568	159	128	0.009	0.009	NUM
bionys-568	159	129	(	(	PUNCT
bionys-568	159	130	0.002	0.002	NUM
bionys-568	159	131	-	-	PUNCT
bionys-568	159	132	0.044	0.044	NUM
bionys-568	159	133	)	)	PUNCT
bionys-568	159	134	<	<	X
bionys-568	159	135	0.001	0.001	NUM
bionys-568	159	136	*	*	SYM
bionys-568	159	137	0.024	0.024	NUM
bionys-568	159	138	(	(	PUNCT
bionys-568	159	139	0.0076	0.0076	NUM
bionys-568	159	140	-	-	PUNCT
bionys-568	159	141	0.078	0.078	NUM
bionys-568	159	142	)	)	PUNCT
bionys-568	159	143	allele	allele	NOUN
bionys-568	159	144	g	g	ADP
bionys-568	159	145	r	r	NOUN
bionys-568	159	146	t	t	X
bionys-568	159	147	<	<	X
bionys-568	159	148	0.001	0.001	NUM
bionys-568	159	149	*	*	SYM
bionys-568	159	150	0.12	0.12	NUM
bionys-568	159	151	(	(	PUNCT
bionys-568	159	152	0.08	0.08	NUM
bionys-568	159	153	-	-	SYM
bionys-568	159	154	0.74	0.74	NUM
bionys-568	159	155	)	)	PUNCT
bionys-568	159	156	<	<	X
bionys-568	159	157	0.001	0.001	NUM
bionys-568	159	158	*	*	SYM
bionys-568	159	159	0.01	0.01	NUM
bionys-568	159	160	(	(	PUNCT
bionys-568	159	161	0.05	0.05	NUM
bionys-568	159	162	-	-	SYM
bionys-568	159	163	0.20	0.20	NUM
bionys-568	159	164	)	)	PUNCT
bionys-568	159	165	<	<	X
bionys-568	159	166	0.001	0.001	NUM
bionys-568	159	167	*	*	SYM
bionys-568	159	168	0.12	0.12	NUM
bionys-568	159	169	(	(	PUNCT
bionys-568	159	170	0.063	0.063	NUM
bionys-568	159	171	-	-	SYM
bionys-568	159	172	0.52	0.52	NUM
bionys-568	159	173	)	)	PUNCT
bionys-568	159	174	rs846910	rs846910	NOUN
bionys-568	159	175	genotype	genotype	NOUN
bionys-568	159	176	gg	gg	NOUN
bionys-568	159	177	<	<	X
bionys-568	159	178	0.001	0.001	NUM
bionys-568	159	179	*	*	NUM
bionys-568	159	180	0.045	0.045	NUM
bionys-568	159	181	(	(	PUNCT
bionys-568	159	182	0.016	0.016	NUM
bionys-568	159	183	-	-	PUNCT
bionys-568	159	184	0.130	0.130	NUM
bionys-568	159	185	)	)	PUNCT
bionys-568	159	186	<	<	X
bionys-568	159	187	0.001	0.001	NUM
bionys-568	159	188	*	*	SYM
bionys-568	159	189	0.53	0.53	NUM
bionys-568	159	190	(	(	PUNCT
bionys-568	159	191	0.018	0.018	NUM
bionys-568	159	192	-	-	PUNCT
bionys-568	159	193	0.03	0.03	NUM
bionys-568	159	194	)	)	PUNCT
bionys-568	159	195	<	<	X
bionys-568	159	196	0.001	0.001	NUM
bionys-568	159	197	*	*	SYM
bionys-568	159	198	0.024	0.024	NUM
bionys-568	159	199	(	(	PUNCT
bionys-568	159	200	0.007	0.007	NUM
bionys-568	159	201	-	-	PUNCT
bionys-568	159	202	0.083	0.083	NUM
bionys-568	159	203	)	)	PUNCT
bionys-568	159	204	ga	ga	PROPN
bionys-568	159	205	<	<	X
bionys-568	159	206	0.001	0.001	NUM
bionys-568	159	207	*	*	SYM
bionys-568	159	208	21.77	21.77	NUM
bionys-568	159	209	(	(	PUNCT
bionys-568	159	210	7.68	7.68	NUM
bionys-568	159	211	-	-	SYM
bionys-568	159	212	61.74	61.74	NUM
bionys-568	159	213	)	)	PUNCT
bionys-568	159	214	<	<	X
bionys-568	159	215	0.001	0.001	NUM
bionys-568	159	216	*	*	SYM
bionys-568	159	217	19.11	19.11	NUM
bionys-568	159	218	(	(	PUNCT
bionys-568	159	219	0.51	0.51	NUM
bionys-568	159	220	-	-	SYM
bionys-568	159	221	0.64	0.64	NUM
bionys-568	159	222	)	)	PUNCT
bionys-568	159	223	<	<	X
bionys-568	159	224	0.001	0.001	NUM
bionys-568	159	225	*	*	SYM
bionys-568	159	226	40.77	40.77	NUM
bionys-568	159	227	(	(	PUNCT
bionys-568	159	228	12.02	12.02	NUM
bionys-568	159	229	-	-	SYM
bionys-568	159	230	138.29	138.29	NUM
bionys-568	159	231	)	)	PUNCT
bionys-568	159	232	allele	allele	NOUN
bionys-568	159	233	g	g	ADP
bionys-568	159	234	r	r	NOUN
bionys-568	159	235	a	a	DET
bionys-568	159	236	<	<	NOUN
bionys-568	159	237	0.001	0.001	NUM
bionys-568	159	238	*	*	SYM
bionys-568	159	239	0.84	0.84	NUM
bionys-568	159	240	(	(	PUNCT
bionys-568	159	241	0.48	0.48	NUM
bionys-568	159	242	-	-	SYM
bionys-568	159	243	1.48	1.48	NUM
bionys-568	159	244	)	)	PUNCT
bionys-568	159	245	<	<	X
bionys-568	159	246	0.001	0.001	NUM
bionys-568	159	247	*	*	SYM
bionys-568	159	248	18.10	18.10	NUM
bionys-568	159	249	(	(	PUNCT
bionys-568	159	250	6.17	6.17	NUM
bionys-568	159	251	-	-	SYM
bionys-568	159	252	53.08	53.08	NUM
bionys-568	159	253	)	)	PUNCT
bionys-568	159	254	<	<	X
bionys-568	159	255	0.001	0.001	NUM
bionys-568	159	256	*	*	SYM
bionys-568	159	257	15.86	15.86	NUM
bionys-568	159	258	(	(	PUNCT
bionys-568	159	259	5.39	5.39	NUM
bionys-568	159	260	-	-	SYM
bionys-568	159	261	46.66	46.66	NUM
bionys-568	159	262	)	)	PUNCT
bionys-568	159	263	p1	p1	PROPN
bionys-568	159	264	hcc	hcc	PROPN
bionys-568	159	265	vs	vs	ADP
bionys-568	159	266	hbv	hbv	NOUN
bionys-568	159	267	,	,	PUNCT
bionys-568	159	268	p2	p2	PROPN
bionys-568	159	269	hcc	hcc	PROPN
bionys-568	159	270	vs	vs	ADP
bionys-568	159	271	control	control	PROPN
bionys-568	159	272	,	,	PUNCT
bionys-568	159	273	p3	p3	PROPN
bionys-568	159	274	–	–	PUNCT
bionys-568	159	275	hbv	hbv	NOUN
bionys-568	159	276	vs	vs	ADP
bionys-568	159	277	control	control	NOUN
bionys-568	159	278	,	,	PUNCT
bionys-568	159	279	or1	or1	PROPN
bionys-568	159	280	hcc	hcc	PROPN
bionys-568	159	281	vs	vs	ADP
bionys-568	159	282	hbv	hbv	PROPN
bionys-568	159	283	,	,	PUNCT
bionys-568	159	284	or2	or2	PROPN
bionys-568	159	285	hcc	hcc	PROPN
bionys-568	159	286	vs	vs	ADP
bionys-568	159	287	control	control	PROPN
bionys-568	159	288	,	,	PUNCT
bionys-568	159	289	or3	or3	PROPN
bionys-568	159	290	hbv	hbv	PROPN
bionys-568	159	291	vs	vs	ADP
bionys-568	159	292	control	control	NOUN
bionys-568	159	293	,	,	PUNCT
bionys-568	159	294	ci	ci	NOUN
bionys-568	159	295	confidence	confidence	NOUN
bionys-568	159	296	interval	interval	NOUN
bionys-568	159	297	,	,	PUNCT
bionys-568	159	298	*	*	PUNCT
bionys-568	159	299	statistically	statistically	ADV
bionys-568	159	300	significant	significant	ADJ
bionys-568	159	301	at	at	ADP
bionys-568	159	302	p≤0.05	p≤0.05	NOUN
bionys-568	159	303	roles	role	NOUN
bionys-568	159	304	in	in	ADP
bionys-568	159	305	regulating	regulate	VERB
bionys-568	159	306	biological	biological	ADJ
bionys-568	159	307	processes	process	NOUN
bionys-568	159	308	associated	associate	VERB
bionys-568	159	309	with	with	ADP
bionys-568	159	310	liver	liver	NOUN
bionys-568	159	311	disease	disease	NOUN
bionys-568	159	312	progression	progression	NOUN
bionys-568	159	313	.	.	PUNCT
bionys-568	160	1	the	the	DET
bionys-568	160	2	defect	defect	NOUN
bionys-568	160	3	in	in	ADP
bionys-568	160	4	the	the	DET
bionys-568	160	5	hepatitis	hepatitis	PROPN
bionys-568	160	6	b	b	PROPN
bionys-568	160	7	virus	virus	NOUN
bionys-568	160	8	11β	11β	NOUN
bionys-568	160	9	-	-	PUNCT
bionys-568	160	10	hsd1	hsd1	PROPN
bionys-568	160	11	gene	gene	NOUN
bionys-568	160	12	rs12086634	rs12086634	PROPN
bionys-568	160	13	demonstrates	demonstrate	VERB
bionys-568	160	14	its	its	PRON
bionys-568	160	15	importance	importance	NOUN
bionys-568	160	16	in	in	ADP
bionys-568	160	17	the	the	DET
bionys-568	160	18	pathogenesis	pathogenesis	NOUN
bionys-568	160	19	of	of	ADP
bionys-568	160	20	this	this	DET
bionys-568	160	21	virus	virus	NOUN
bionys-568	160	22	and	and	CCONJ
bionys-568	160	23	highlights	highlight	NOUN
bionys-568	160	24	the	the	DET
bionys-568	160	25	importance	importance	NOUN
bionys-568	160	26	of	of	ADP
bionys-568	160	27	the	the	DET
bionys-568	160	28	11β	11β	NUM
bionys-568	160	29	-	-	PUNCT
bionys-568	160	30	hsd1	hsd1	ADJ
bionys-568	160	31	rs846910	rs846910	NOUN
bionys-568	160	32	and	and	CCONJ
bionys-568	160	33	rs12086634	rs12086634	PROPN
bionys-568	160	34	gene	gene	NOUN
bionys-568	160	35	polymorphisms	polymorphism	NOUN
bionys-568	160	36	in	in	ADP
bionys-568	160	37	understanding	understand	VERB
bionys-568	160	38	the	the	DET
bionys-568	160	39	genetic	genetic	ADJ
bionys-568	160	40	basis	basis	NOUN
bionys-568	160	41	of	of	ADP
bionys-568	160	42	hepatocellular	hepatocellular	ADJ
bionys-568	160	43	carcinoma	carcinoma	NOUN
bionys-568	160	44	and	and	CCONJ
bionys-568	160	45	hepatitis	hepatitis	PROPN
bionys-568	160	46	b	b	PROPN
bionys-568	160	47	virus	virus	NOUN
bionys-568	160	48	.	.	PUNCT
bionys-568	161	1	future	future	ADJ
bionys-568	161	2	studies	study	NOUN
bionys-568	161	3	require	require	VERB
bionys-568	161	4	increasing	increase	VERB
bionys-568	161	5	the	the	DET
bionys-568	161	6	sample	sample	NOUN
bionys-568	161	7	size	size	NOUN
bionys-568	161	8	and	and	CCONJ
bionys-568	161	9	further	further	ADJ
bionys-568	161	10	functional	functional	ADJ
bionys-568	161	11	analyses	analysis	NOUN
bionys-568	161	12	to	to	PART
bionys-568	161	13	confirm	confirm	VERB
bionys-568	161	14	the	the	DET
bionys-568	161	15	results	result	NOUN
bionys-568	161	16	and	and	CCONJ
bionys-568	161	17	to	to	PART
bionys-568	161	18	elucidate	elucidate	VERB
bionys-568	161	19	the	the	DET
bionys-568	161	20	mechanisms	mechanism	NOUN
bionys-568	161	21	underlying	underlie	VERB
bionys-568	161	22	this	this	DET
bionys-568	161	23	association	association	NOUN
bionys-568	161	24	.	.	PUNCT
bionys-568	162	1	hepatocellular	hepatocellular	ADJ
bionys-568	162	2	carcinoma	carcinoma	NOUN
bionys-568	162	3	(	(	PUNCT
bionys-568	162	4	hcc	hcc	NOUN
bionys-568	162	5	)	)	PUNCT
bionys-568	162	6	constitutes	constitute	VERB
bionys-568	162	7	a	a	DET
bionys-568	162	8	significant	significant	ADJ
bionys-568	162	9	public	public	ADJ
bionys-568	162	10	health	health	NOUN
bionys-568	162	11	issue	issue	NOUN
bionys-568	162	12	,	,	PUNCT
bionys-568	162	13	with	with	ADP
bionys-568	162	14	an	an	DET
bionys-568	162	15	expected	expect	VERB
bionys-568	162	16	905,677	905,677	NUM
bionys-568	162	17	new	new	ADJ
bionys-568	162	18	cases	case	NOUN
bionys-568	162	19	and	and	CCONJ
bionys-568	162	20	830,180	830,180	NUM
bionys-568	162	21	fatalities	fatality	NOUN
bionys-568	162	22	reported	report	VERB
bionys-568	162	23	globally	globally	ADV
bionys-568	162	24	in	in	ADP
bionys-568	162	25	2020	2020	NUM
bionys-568	162	26	.	.	PUNCT
bionys-568	163	1	consequently	consequently	ADV
bionys-568	163	2	,	,	PUNCT
bionys-568	163	3	hcc	hcc	PROPN
bionys-568	163	4	is	be	AUX
bionys-568	163	5	projected	project	VERB
bionys-568	163	6	to	to	PART
bionys-568	163	7	be	be	AUX
bionys-568	163	8	the	the	DET
bionys-568	163	9	third	third	ADJ
bionys-568	163	10	most	most	ADV
bionys-568	163	11	fatal	fatal	ADJ
bionys-568	163	12	cancer	cancer	NOUN
bionys-568	163	13	form	form	NOUN
bionys-568	163	14	,	,	PUNCT
bionys-568	163	15	mostly	mostly	ADV
bionys-568	163	16	due	due	ADJ
bionys-568	163	17	to	to	ADP
bionys-568	163	18	diagnostic	diagnostic	ADJ
bionys-568	163	19	delays	delay	NOUN
bionys-568	163	20	and	and	CCONJ
bionys-568	163	21	insufficiently	insufficiently	ADV
bionys-568	163	22	efficient	efficient	ADJ
bionys-568	163	23	treatment	treatment	NOUN
bionys-568	163	24	techniques	technique	NOUN
bionys-568	163	25	(	(	PUNCT
bionys-568	163	26	sung	sing	VERB
bionys-568	163	27	et	et	PROPN
bionys-568	163	28	al	al	PROPN
bionys-568	163	29	.	.	PROPN
bionys-568	163	30	,	,	PUNCT
bionys-568	163	31	2021	2021	NUM
bionys-568	163	32	)	)	PUNCT
bionys-568	163	33	.	.	PUNCT
bionys-568	164	1	nearly	nearly	ADV
bionys-568	164	2	90	90	NUM
bionys-568	164	3	%	%	NOUN
bionys-568	164	4	of	of	ADP
bionys-568	164	5	all	all	DET
bionys-568	164	6	hcc	hcc	PROPN
bionys-568	164	7	cases	case	NOUN
bionys-568	164	8	are	be	AUX
bionys-568	164	9	associated	associate	VERB
bionys-568	164	10	with	with	ADP
bionys-568	164	11	identifiable	identifiable	ADJ
bionys-568	164	12	risk	risk	NOUN
bionys-568	164	13	factors	factor	NOUN
bionys-568	164	14	,	,	PUNCT
bionys-568	164	15	namely	namely	ADV
bionys-568	164	16	chronic	chronic	ADJ
bionys-568	164	17	viral	viral	ADJ
bionys-568	164	18	hepatitis	hepatitis	NOUN
bionys-568	164	19	and	and	CCONJ
bionys-568	164	20	alcohol	alcohol	NOUN
bionys-568	164	21	misuse	misuse	NOUN
bionys-568	164	22	.	.	PUNCT
bionys-568	165	1	chronic	chronic	ADJ
bionys-568	165	2	infection	infection	NOUN
bionys-568	165	3	with	with	ADP
bionys-568	165	4	hepatitis	hepatitis	PROPN
bionys-568	165	5	b	b	PROPN
bionys-568	165	6	virus	virus	NOUN
bionys-568	165	7	(	(	PUNCT
bionys-568	165	8	hbv	hbv	NOUN
bionys-568	165	9	)	)	PUNCT
bionys-568	165	10	is	be	AUX
bionys-568	165	11	the	the	DET
bionys-568	165	12	primary	primary	ADJ
bionys-568	165	13	cause	cause	NOUN
bionys-568	165	14	of	of	ADP
bionys-568	165	15	hcc	hcc	PROPN
bionys-568	165	16	globally	globally	ADV
bionys-568	165	17	,	,	PUNCT
bionys-568	165	18	succeeded	succeed	VERB
bionys-568	165	19	by	by	ADP
bionys-568	165	20	chronic	chronic	ADJ
bionys-568	165	21	infection	infection	NOUN
bionys-568	165	22	with	with	ADP
bionys-568	165	23	hepatitis	hepatitis	PROPN
bionys-568	165	24	c	c	PROPN
bionys-568	165	25	virus	virus	NOUN
bionys-568	165	26	(	(	PUNCT
bionys-568	165	27	hcv	hcv	PROPN
bionys-568	165	28	)	)	PUNCT
bionys-568	165	29	(	(	PUNCT
bionys-568	165	30	galle	galle	PROPN
bionys-568	165	31	et	et	PROPN
bionys-568	165	32	al	al	PROPN
bionys-568	165	33	.	.	PROPN
bionys-568	165	34	,	,	PUNCT
bionys-568	165	35	2018	2018	NUM
bionys-568	165	36	;	;	PUNCT
bionys-568	165	37	alkhaykanee	alkhaykanee	NOUN
bionys-568	165	38	et	et	PROPN
bionys-568	165	39	al	al	PROPN
bionys-568	165	40	.	.	PROPN
bionys-568	165	41	,	,	PUNCT
bionys-568	165	42	2021	2021	NUM
bionys-568	165	43	)	)	PUNCT
bionys-568	165	44	.	.	PUNCT
bionys-568	166	1	consequently	consequently	ADV
bionys-568	166	2	,	,	PUNCT
bionys-568	166	3	the	the	DET
bionys-568	166	4	world	world	PROPN
bionys-568	166	5	health	health	NOUN
bionys-568	166	6	organization	organization	NOUN
bionys-568	166	7	has	have	AUX
bionys-568	166	8	designated	designate	VERB
bionys-568	166	9	hbv	hbv	NOUN
bionys-568	166	10	and	and	CCONJ
bionys-568	166	11	hcv	hcv	PROPN
bionys-568	166	12	as	as	ADP
bionys-568	166	13	oncoviruses	oncoviruse	NOUN
bionys-568	166	14	(	(	PUNCT
bionys-568	166	15	mesri	mesri	INTJ
bionys-568	166	16	et	et	PROPN
bionys-568	166	17	al	al	PROPN
bionys-568	166	18	.	.	PROPN
bionys-568	166	19	,	,	PUNCT
bionys-568	166	20	2014	2014	NUM
bionys-568	166	21	)	)	PUNCT
bionys-568	166	22	.	.	PUNCT
bionys-568	167	1	hepatitis	hepatitis	PROPN
bionys-568	167	2	b	b	PROPN
bionys-568	167	3	contributes	contribute	VERB
bionys-568	167	4	directly	directly	ADV
bionys-568	167	5	or	or	CCONJ
bionys-568	167	6	indirectly	indirectly	ADV
bionys-568	167	7	to	to	PART
bionys-568	167	8	liver	liver	NOUN
bionys-568	167	9	cancer	cancer	NOUN
bionys-568	167	10	by	by	ADP
bionys-568	167	11	destabilizing	destabilize	VERB
bionys-568	167	12	the	the	DET
bionys-568	167	13	cell	cell	NOUN
bionys-568	167	14	genome	genome	NOUN
bionys-568	167	15	and	and	CCONJ
bionys-568	167	16	producing	produce	VERB
bionys-568	167	17	genetic	genetic	ADJ
bionys-568	167	18	modifications	modification	NOUN
bionys-568	167	19	in	in	ADP
bionys-568	167	20	the	the	DET
bionys-568	167	21	host	host	NOUN
bionys-568	167	22	dna	dna	NOUN
bionys-568	167	23	,	,	PUNCT
bionys-568	167	24	leading	lead	VERB
bionys-568	167	25	to	to	ADP
bionys-568	167	26	chromosomal	chromosomal	ADJ
bionys-568	167	27	reconfiguration	reconfiguration	NOUN
bionys-568	167	28	and	and	CCONJ
bionys-568	167	29	aberrant	aberrant	ADJ
bionys-568	167	30	293	293	NUM
bionys-568	167	31	activation	activation	NOUN
bionys-568	167	32	of	of	ADP
bionys-568	167	33	oncogenes	oncogene	NOUN
bionys-568	167	34	and	and	CCONJ
bionys-568	167	35	tumor	tumor	NOUN
bionys-568	167	36	suppressor	suppressor	NOUN
bionys-568	167	37	genes	gene	NOUN
bionys-568	167	38	through	through	ADP
bionys-568	167	39	integration	integration	NOUN
bionys-568	167	40	or	or	CCONJ
bionys-568	167	41	mutation	mutation	NOUN
bionys-568	167	42	of	of	ADP
bionys-568	167	43	host	host	NOUN
bionys-568	167	44	genes	gene	NOUN
bionys-568	167	45	.	.	PUNCT
bionys-568	168	1	it	it	PRON
bionys-568	168	2	may	may	AUX
bionys-568	168	3	also	also	ADV
bionys-568	168	4	induce	induce	VERB
bionys-568	168	5	malignant	malignant	ADJ
bionys-568	168	6	transformation	transformation	NOUN
bionys-568	168	7	of	of	ADP
bionys-568	168	8	hepatocytes	hepatocyte	NOUN
bionys-568	168	9	by	by	ADP
bionys-568	168	10	activating	activate	VERB
bionys-568	168	11	various	various	ADJ
bionys-568	168	12	cancer	cancer	NOUN
bionys-568	168	13	-	-	PUNCT
bionys-568	168	14	related	relate	VERB
bionys-568	168	15	signaling	signal	VERB
bionys-568	168	16	pathways	pathway	NOUN
bionys-568	168	17	(	(	PUNCT
bionys-568	168	18	jiang	jiang	PROPN
bionys-568	168	19	et	et	PROPN
bionys-568	168	20	al	al	PROPN
bionys-568	168	21	.	.	PROPN
bionys-568	168	22	,	,	PUNCT
bionys-568	168	23	2021	2021	NUM
bionys-568	168	24	)	)	PUNCT
bionys-568	168	25	.	.	PUNCT
bionys-568	169	1	11beta	11beta	X
bionys-568	169	2	-	-	PUNCT
bionys-568	169	3	hydroxysteroid	hydroxysteroid	ADJ
bionys-568	169	4	dehydrogenase	dehydrogenase	NOUN
bionys-568	169	5	type	type	NOUN
bionys-568	169	6	1	1	NUM
bionys-568	169	7	(	(	PUNCT
bionys-568	169	8	11β	11β	NOUN
bionys-568	169	9	-	-	PUNCT
bionys-568	169	10	hsd1	hsd1	PROPN
bionys-568	169	11	)	)	PUNCT
bionys-568	169	12	catalyzes	catalyze	VERB
bionys-568	169	13	the	the	DET
bionys-568	169	14	conversion	conversion	NOUN
bionys-568	169	15	of	of	ADP
bionys-568	169	16	glucocorticoids	glucocorticoid	NOUN
bionys-568	169	17	from	from	ADP
bionys-568	169	18	the	the	DET
bionys-568	169	19	inactive	inactive	ADJ
bionys-568	169	20	cortisone	cortisone	NOUN
bionys-568	169	21	to	to	ADP
bionys-568	169	22	the	the	DET
bionys-568	169	23	active	active	ADJ
bionys-568	169	24	cortisol	cortisol	NOUN
bionys-568	169	25	,	,	PUNCT
bionys-568	169	26	serving	serve	VERB
bionys-568	169	27	a	a	DET
bionys-568	169	28	vital	vital	ADJ
bionys-568	169	29	role	role	NOUN
bionys-568	169	30	in	in	ADP
bionys-568	169	31	glycemic	glycemic	ADJ
bionys-568	169	32	regulation	regulation	NOUN
bionys-568	169	33	.	.	PUNCT
bionys-568	170	1	growing	grow	VERB
bionys-568	170	2	evidence	evidence	NOUN
bionys-568	170	3	suggests	suggest	VERB
bionys-568	170	4	that	that	SCONJ
bionys-568	170	5	heightened	heighten	VERB
bionys-568	170	6	glycolytic	glycolytic	ADJ
bionys-568	170	7	activity	activity	NOUN
bionys-568	170	8	is	be	AUX
bionys-568	170	9	significantly	significantly	ADV
bionys-568	170	10	associated	associate	VERB
bionys-568	170	11	with	with	ADP
bionys-568	170	12	postoperative	postoperative	ADJ
bionys-568	170	13	recurrence	recurrence	NOUN
bionys-568	170	14	and	and	CCONJ
bionys-568	170	15	prognosis	prognosis	NOUN
bionys-568	170	16	of	of	ADP
bionys-568	170	17	hepatocellular	hepatocellular	ADJ
bionys-568	170	18	carcinoma	carcinoma	NOUN
bionys-568	170	19	(	(	PUNCT
bionys-568	170	20	hcc	hcc	PROPN
bionys-568	170	21	)	)	PUNCT
bionys-568	170	22	(	(	PUNCT
bionys-568	170	23	liu	liu	PROPN
bionys-568	170	24	et	et	PROPN
bionys-568	170	25	al	al	PROPN
bionys-568	170	26	.	.	PROPN
bionys-568	170	27	,	,	PUNCT
bionys-568	170	28	2015	2015	NUM
bionys-568	170	29	)	)	PUNCT
bionys-568	170	30	.	.	PUNCT
bionys-568	171	1	in	in	ADP
bionys-568	171	2	this	this	DET
bionys-568	171	3	study	study	NOUN
bionys-568	171	4	,	,	PUNCT
bionys-568	171	5	the	the	DET
bionys-568	171	6	polymorphism	polymorphism	NOUN
bionys-568	171	7	of	of	ADP
bionys-568	171	8	the	the	DET
bionys-568	171	9	11β	11β	NOUN
bionys-568	171	10	-	-	PUNCT
bionys-568	171	11	hsd1	hsd1	VERB
bionys-568	171	12	gen	gen	PROPN
bionys-568	171	13	g	g	PROPN
bionys-568	171	14	/	/	SYM
bionys-568	171	15	t	t	PROPN
bionys-568	171	16	was	be	AUX
bionys-568	171	17	evaluated	evaluate	VERB
bionys-568	171	18	in	in	ADP
bionys-568	171	19	the	the	DET
bionys-568	171	20	three	three	NUM
bionys-568	171	21	studied	study	VERB
bionys-568	171	22	groups	group	NOUN
bionys-568	171	23	(	(	PUNCT
bionys-568	171	24	hcc	hcc	PROPN
bionys-568	171	25	,	,	PUNCT
bionys-568	171	26	hbv	hbv	NOUN
bionys-568	171	27	and	and	CCONJ
bionys-568	171	28	control	control	NOUN
bionys-568	171	29	group	group	NOUN
bionys-568	171	30	)	)	PUNCT
bionys-568	171	31	.	.	PUNCT
bionys-568	172	1	analyses	analysis	NOUN
bionys-568	172	2	revealed	reveal	VERB
bionys-568	172	3	significant	significant	ADJ
bionys-568	172	4	measurable	measurable	ADJ
bionys-568	172	5	variations	variation	NOUN
bionys-568	172	6	in	in	ADP
bionys-568	172	7	genotype	genotype	NOUN
bionys-568	172	8	and	and	CCONJ
bionys-568	172	9	allele	allele	NOUN
bionys-568	172	10	frequency	frequency	NOUN
bionys-568	172	11	of	of	ADP
bionys-568	172	12	the	the	DET
bionys-568	172	13	11β	11β	NUM
bionys-568	172	14	-	-	PUNCT
bionys-568	172	15	hsd1	hsd1	VERB
bionys-568	172	16	rs12086634	rs12086634	PROPN
bionys-568	172	17	gene	gene	NOUN
bionys-568	172	18	.	.	PUNCT
bionys-568	173	1	the	the	DET
bionys-568	173	2	increase	increase	NOUN
bionys-568	173	3	was	be	AUX
bionys-568	173	4	with	with	ADP
bionys-568	173	5	the	the	DET
bionys-568	173	6	prevalence	prevalence	NOUN
bionys-568	173	7	of	of	ADP
bionys-568	173	8	the	the	DET
bionys-568	173	9	g	g	PROPN
bionys-568	173	10	/	/	SYM
bionys-568	173	11	t	t	PROPN
bionys-568	173	12	genotype	genotype	NOUN
bionys-568	173	13	in	in	ADP
bionys-568	173	14	hcc	hcc	PROPN
bionys-568	173	15	patients	patient	NOUN
bionys-568	173	16	and	and	CCONJ
bionys-568	173	17	its	its	PRON
bionys-568	173	18	presence	presence	NOUN
bionys-568	173	19	was	be	AUX
bionys-568	173	20	higher	high	ADJ
bionys-568	173	21	than	than	ADP
bionys-568	173	22	in	in	ADP
bionys-568	173	23	patients	patient	NOUN
bionys-568	173	24	infected	infect	VERB
bionys-568	173	25	with	with	ADP
bionys-568	173	26	hbv	hbv	NOUN
bionys-568	173	27	only	only	ADV
bionys-568	173	28	.	.	PUNCT
bionys-568	174	1	the	the	DET
bionys-568	174	2	tt	tt	PROPN
bionys-568	174	3	genotype	genotype	NOUN
bionys-568	174	4	was	be	AUX
bionys-568	174	5	the	the	DET
bionys-568	174	6	most	most	ADV
bionys-568	174	7	common	common	ADJ
bionys-568	174	8	in	in	ADP
bionys-568	174	9	the	the	DET
bionys-568	174	10	control	control	NOUN
bionys-568	174	11	group	group	NOUN
bionys-568	174	12	,	,	PUNCT
bionys-568	174	13	as	as	SCONJ
bionys-568	174	14	the	the	DET
bionys-568	174	15	t	t	PROPN
bionys-568	174	16	allele	allele	NOUN
bionys-568	174	17	is	be	AUX
bionys-568	174	18	associated	associate	VERB
bionys-568	174	19	with	with	ADP
bionys-568	174	20	resistance	resistance	NOUN
bionys-568	174	21	to	to	ADP
bionys-568	174	22	hbv	hbv	NOUN
bionys-568	174	23	infection	infection	NOUN
bionys-568	174	24	and	and	CCONJ
bionys-568	174	25	is	be	AUX
bionys-568	174	26	considered	consider	VERB
bionys-568	174	27	defensive	defensive	ADJ
bionys-568	174	28	against	against	ADP
bionys-568	174	29	the	the	DET
bionys-568	174	30	development	development	NOUN
bionys-568	174	31	of	of	ADP
bionys-568	174	32	hcc	hcc	PROPN
bionys-568	174	33	.	.	PUNCT
bionys-568	175	1	in	in	ADP
bionys-568	175	2	this	this	DET
bionys-568	175	3	study	study	NOUN
bionys-568	175	4	,	,	PUNCT
bionys-568	175	5	we	we	PRON
bionys-568	175	6	observed	observe	VERB
bionys-568	175	7	the	the	DET
bionys-568	175	8	distribution	distribution	NOUN
bionys-568	175	9	of	of	ADP
bionys-568	175	10	the	the	DET
bionys-568	175	11	11β	11β	NOUN
bionys-568	175	12	-	-	PUNCT
bionys-568	175	13	hsd1	hsd1	ADJ
bionys-568	175	14	rs846910	rs846910	NOUN
bionys-568	175	15	genotype	genotype	NOUN
bionys-568	175	16	among	among	ADP
bionys-568	175	17	the	the	DET
bionys-568	175	18	three	three	NUM
bionys-568	175	19	studied	study	VERB
bionys-568	175	20	groups	group	NOUN
bionys-568	175	21	,	,	PUNCT
bionys-568	175	22	where	where	SCONJ
bionys-568	175	23	the	the	DET
bionys-568	175	24	ga	ga	PROPN
bionys-568	175	25	genotype	genotype	NOUN
bionys-568	175	26	was	be	AUX
bionys-568	175	27	slightly	slightly	ADV
bionys-568	175	28	more	more	ADV
bionys-568	175	29	prevalent	prevalent	ADJ
bionys-568	175	30	in	in	ADP
bionys-568	175	31	hcc	hcc	PROPN
bionys-568	175	32	patients	patient	NOUN
bionys-568	175	33	than	than	ADP
bionys-568	175	34	in	in	ADP
bionys-568	175	35	kidney	kidney	NOUN
bionys-568	175	36	infection	infection	NOUN
bionys-568	175	37	only	only	ADV
bionys-568	175	38	,	,	PUNCT
bionys-568	175	39	while	while	SCONJ
bionys-568	175	40	the	the	DET
bionys-568	175	41	ga	ga	PROPN
bionys-568	175	42	genotype	genotype	NOUN
bionys-568	175	43	was	be	AUX
bionys-568	175	44	more	more	ADV
bionys-568	175	45	normal	normal	ADJ
bionys-568	175	46	in	in	ADP
bionys-568	175	47	the	the	DET
bionys-568	175	48	control	control	NOUN
bionys-568	175	49	group	group	NOUN
bionys-568	175	50	.	.	PUNCT
bionys-568	176	1	in	in	ADP
bionys-568	176	2	general	general	ADJ
bionys-568	176	3	,	,	PUNCT
bionys-568	176	4	the	the	DET
bionys-568	176	5	distribution	distribution	NOUN
bionys-568	176	6	of	of	ADP
bionys-568	176	7	the	the	DET
bionys-568	176	8	aa	aa	PROPN
bionys-568	176	9	genotype	genotype	NOUN
bionys-568	176	10	was	be	AUX
bionys-568	176	11	less	less	ADV
bionys-568	176	12	prevalent	prevalent	ADJ
bionys-568	176	13	.	.	PUNCT
bionys-568	177	1	in	in	ADP
bionys-568	177	2	this	this	DET
bionys-568	177	3	study	study	NOUN
bionys-568	177	4	,	,	PUNCT
bionys-568	177	5	we	we	PRON
bionys-568	177	6	investigated	investigate	VERB
bionys-568	177	7	11β	11β	NOUN
bionys-568	177	8	-	-	PUNCT
bionys-568	177	9	hsd1	hsd1	PROPN
bionys-568	177	10	gene	gene	NOUN
bionys-568	177	11	association	association	NOUN
bionys-568	177	12	with	with	ADP
bionys-568	177	13	certain	certain	ADJ
bionys-568	177	14	diseases	disease	NOUN
bionys-568	177	15	,	,	PUNCT
bionys-568	177	16	explored	explore	VERB
bionys-568	177	17	the	the	DET
bionys-568	177	18	relationship	relationship	NOUN
bionys-568	177	19	of	of	ADP
bionys-568	177	20	the	the	DET
bionys-568	177	21	polymorphism	polymorphism	NOUN
bionys-568	177	22	of	of	ADP
bionys-568	177	23	these	these	DET
bionys-568	177	24	gene	gene	NOUN
bionys-568	177	25	with	with	ADP
bionys-568	177	26	hbv	hbv	NOUN
bionys-568	177	27	risk	risk	NOUN
bionys-568	177	28	and	and	CCONJ
bionys-568	177	29	hcc	hcc	PROPN
bionys-568	177	30	contaminated	contaminate	VERB
bionys-568	177	31	patients	patient	NOUN
bionys-568	177	32	.	.	PUNCT
bionys-568	178	1	11β	11β	NOUN
bionys-568	178	2	-	-	PUNCT
bionys-568	178	3	hsd1	hsd1	PROPN
bionys-568	178	4	is	be	AUX
bionys-568	178	5	present	present	ADJ
bionys-568	178	6	in	in	ADP
bionys-568	178	7	the	the	DET
bionys-568	178	8	liver	liver	NOUN
bionys-568	178	9	,	,	PUNCT
bionys-568	178	10	adipose	adipose	ADJ
bionys-568	178	11	tissue	tissue	NOUN
bionys-568	178	12	,	,	PUNCT
bionys-568	178	13	and	and	CCONJ
bionys-568	178	14	kidneys	kidney	NOUN
bionys-568	178	15	,	,	PUNCT
bionys-568	178	16	among	among	ADP
bionys-568	178	17	other	other	ADJ
bionys-568	178	18	organs	organ	NOUN
bionys-568	178	19	,	,	PUNCT
bionys-568	178	20	and	and	CCONJ
bionys-568	178	21	performs	perform	VERB
bionys-568	178	22	multiple	multiple	ADJ
bionys-568	178	23	physiological	physiological	ADJ
bionys-568	178	24	functions	function	NOUN
bionys-568	178	25	,	,	PUNCT
bionys-568	178	26	including	include	VERB
bionys-568	178	27	intracellular	intracellular	NOUN
bionys-568	178	28	and	and	CCONJ
bionys-568	178	29	oxysterol	oxysterol	NOUN
bionys-568	178	30	metabolism	metabolism	NOUN
bionys-568	178	31	;	;	PUNCT
bionys-568	178	32	its	its	PRON
bionys-568	178	33	dysregulated	dysregulated	ADJ
bionys-568	178	34	expression	expression	NOUN
bionys-568	178	35	is	be	AUX
bionys-568	178	36	linked	link	VERB
bionys-568	178	37	to	to	ADP
bionys-568	178	38	insulin	insulin	NOUN
bionys-568	178	39	resistance	resistance	NOUN
bionys-568	178	40	,	,	PUNCT
bionys-568	178	41	visceral	visceral	ADJ
bionys-568	178	42	adiposity	adiposity	NOUN
bionys-568	178	43	and	and	CCONJ
bionys-568	178	44	hypotension	hypotension	NOUN
bionys-568	178	45	(	(	PUNCT
bionys-568	178	46	seckl	seckl	NOUN
bionys-568	178	47	et	et	PROPN
bionys-568	178	48	al	al	PROPN
bionys-568	178	49	.	.	PROPN
bionys-568	178	50	,	,	PUNCT
bionys-568	178	51	2004	2004	NUM
bionys-568	178	52	)	)	PUNCT
bionys-568	178	53	.	.	PUNCT
bionys-568	179	1	11β	11β	NOUN
bionys-568	179	2	-	-	PUNCT
bionys-568	179	3	hsd1	hsd1	PROPN
bionys-568	179	4	is	be	AUX
bionys-568	179	5	a	a	DET
bionys-568	179	6	microsomal	microsomal	ADJ
bionys-568	179	7	compound	compound	NOUN
bionys-568	179	8	that	that	PRON
bionys-568	179	9	catalyzes	catalyze	VERB
bionys-568	179	10	the	the	DET
bionys-568	179	11	change	change	NOUN
bionys-568	179	12	of	of	ADP
bionys-568	179	13	the	the	DET
bionys-568	179	14	active	active	ADJ
bionys-568	179	15	steroid	steroid	NOUN
bionys-568	179	16	cortisol	cortisol	NOUN
bionys-568	179	17	to	to	ADP
bionys-568	179	18	the	the	DET
bionys-568	179	19	inactive	inactive	ADJ
bionys-568	179	20	metabolite	metabolite	NOUN
bionys-568	179	21	cortisone	cortisone	NOUN
bionys-568	179	22	(	(	PUNCT
bionys-568	179	23	michalaki	michalaki	VERB
bionys-568	179	24	et	et	PROPN
bionys-568	179	25	al	al	PROPN
bionys-568	179	26	.	.	PROPN
bionys-568	179	27	,	,	PUNCT
bionys-568	179	28	2012	2012	NUM
bionys-568	179	29	)	)	PUNCT
bionys-568	179	30	.	.	PUNCT
bionys-568	180	1	the	the	DET
bionys-568	180	2	11β	11β	NUM
bionys-568	180	3	-	-	PUNCT
bionys-568	180	4	hsd1	hsd1	ADJ
bionys-568	180	5	gene	gene	NOUN
bionys-568	180	6	is	be	AUX
bionys-568	180	7	considered	consider	VERB
bionys-568	180	8	as	as	ADP
bionys-568	180	9	hereditary	hereditary	ADJ
bionys-568	180	10	risk	risk	NOUN
bionys-568	180	11	factors	factor	NOUN
bionys-568	180	12	for	for	ADP
bionys-568	180	13	polycystic	polycystic	ADJ
bionys-568	180	14	ovary	ovary	ADJ
bionys-568	180	15	condition	condition	NOUN
bionys-568	180	16	and	and	CCONJ
bionys-568	180	17	could	could	AUX
bionys-568	180	18	potentially	potentially	ADV
bionys-568	180	19	be	be	AUX
bionys-568	180	20	used	use	VERB
bionys-568	180	21	to	to	PART
bionys-568	180	22	evaluate	evaluate	VERB
bionys-568	180	23	for	for	ADP
bionys-568	180	24	early	early	ADJ
bionys-568	180	25	detection	detection	NOUN
bionys-568	180	26	of	of	ADP
bionys-568	180	27	pcos	pcos	PROPN
bionys-568	180	28	(	(	PUNCT
bionys-568	180	29	soliman	soliman	NOUN
bionys-568	180	30	et	et	PROPN
bionys-568	180	31	al	al	PROPN
bionys-568	180	32	.	.	PROPN
bionys-568	180	33	,	,	PUNCT
bionys-568	180	34	2020	2020	NUM
bionys-568	180	35	)	)	PUNCT
bionys-568	180	36	.	.	PUNCT
bionys-568	181	1	furthermore	furthermore	ADV
bionys-568	181	2	,	,	PUNCT
bionys-568	181	3	the	the	DET
bionys-568	181	4	expression	expression	NOUN
bionys-568	181	5	level	level	NOUN
bionys-568	181	6	of	of	ADP
bionys-568	181	7	11β	11β	NOUN
bionys-568	181	8	-	-	PUNCT
bionys-568	181	9	hsd1	hsd1	VERB
bionys-568	181	10	in	in	ADP
bionys-568	181	11	subcutaneous	subcutaneous	ADJ
bionys-568	181	12	adipose	adipose	ADJ
bionys-568	181	13	tissue	tissue	NOUN
bionys-568	181	14	was	be	AUX
bionys-568	181	15	associated	associate	VERB
bionys-568	181	16	with	with	ADP
bionys-568	181	17	fasting	fast	VERB
bionys-568	181	18	plasma	plasma	NOUN
bionys-568	181	19	glucose	glucose	NOUN
bionys-568	181	20	levels	level	NOUN
bionys-568	181	21	and	and	CCONJ
bionys-568	181	22	correlated	correlate	VERB
bionys-568	181	23	with	with	ADP
bionys-568	181	24	lipids	lipid	NOUN
bionys-568	181	25	.	.	PUNCT
bionys-568	182	1	the	the	DET
bionys-568	182	2	gene	gene	NOUN
bionys-568	182	3	expression	expression	NOUN
bionys-568	182	4	of	of	ADP
bionys-568	182	5	11β	11β	NOUN
bionys-568	182	6	-	-	PUNCT
bionys-568	182	7	hsd1	hsd1	NOUN
bionys-568	182	8	significantly	significantly	ADV
bionys-568	182	9	increases	increase	VERB
bionys-568	182	10	the	the	DET
bionys-568	182	11	risk	risk	NOUN
bionys-568	182	12	of	of	ADP
bionys-568	182	13	diabetes	diabetes	NOUN
bionys-568	182	14	mellitus	mellitus	NOUN
bionys-568	182	15	and	and	CCONJ
bionys-568	182	16	hypertension	hypertension	NOUN
bionys-568	182	17	in	in	ADP
bionys-568	182	18	obese	obese	ADJ
bionys-568	182	19	individuals	individual	NOUN
bionys-568	182	20	(	(	PUNCT
bionys-568	182	21	aziz	aziz	PROPN
bionys-568	182	22	et	et	PROPN
bionys-568	182	23	al	al	PROPN
bionys-568	182	24	.	.	PROPN
bionys-568	182	25	,	,	PUNCT
bionys-568	182	26	2023	2023	NUM
bionys-568	182	27	)	)	PUNCT
bionys-568	182	28	.	.	PUNCT
bionys-568	183	1	11β	11β	NOUN
bionys-568	183	2	-	-	PUNCT
bionys-568	183	3	hsd1	hsd1	PROPN
bionys-568	183	4	might	might	AUX
bionys-568	183	5	be	be	AUX
bionys-568	183	6	a	a	DET
bionys-568	183	7	significant	significant	ADJ
bionys-568	183	8	protein	protein	NOUN
bionys-568	183	9	in	in	ADP
bionys-568	183	10	the	the	DET
bionys-568	183	11	pathogenesis	pathogenesis	NOUN
bionys-568	183	12	of	of	ADP
bionys-568	183	13	fatty	fatty	NOUN
bionys-568	183	14	liver	liver	NOUN
bionys-568	183	15	and	and	CCONJ
bionys-568	183	16	obesity	obesity	NOUN
bionys-568	183	17	(	(	PUNCT
bionys-568	183	18	lutz	lutz	PROPN
bionys-568	183	19	et	et	PROPN
bionys-568	183	20	al	al	PROPN
bionys-568	183	21	.	.	PROPN
bionys-568	183	22	,	,	PUNCT
bionys-568	183	23	2016	2016	NUM
bionys-568	183	24	)	)	PUNCT
bionys-568	183	25	.	.	PUNCT
bionys-568	184	1	a	a	DET
bionys-568	184	2	study	study	NOUN
bionys-568	184	3	conducted	conduct	VERB
bionys-568	184	4	by	by	ADP
bionys-568	184	5	shareef	shareef	PROPN
bionys-568	184	6	&	&	CCONJ
bionys-568	184	7	al	al	PROPN
bionys-568	184	8	-	-	PROPN
bionys-568	184	9	attar	attar	PROPN
bionys-568	184	10	(	(	PUNCT
bionys-568	184	11	2019	2019	NUM
bionys-568	184	12	)	)	PUNCT
bionys-568	184	13	confirmed	confirm	VERB
bionys-568	184	14	that	that	SCONJ
bionys-568	184	15	snp	snp	ADJ
bionys-568	184	16	rs2086634	rs2086634	PROPN
bionys-568	184	17	t	t	PROPN
bionys-568	184	18	/	/	SYM
bionys-568	184	19	g	g	NOUN
bionys-568	184	20	of	of	ADP
bionys-568	184	21	the	the	DET
bionys-568	184	22	11β	11β	NOUN
bionys-568	184	23	-	-	PUNCT
bionys-568	184	24	hsd1	hsd1	NOUN
bionys-568	184	25	gene	gene	NOUN
bionys-568	184	26	is	be	AUX
bionys-568	184	27	significantly	significantly	ADV
bionys-568	184	28	associated	associate	VERB
bionys-568	184	29	with	with	ADP
bionys-568	184	30	polycystic	polycystic	ADJ
bionys-568	184	31	ovary	ovary	ADJ
bionys-568	184	32	syndrome	syndrome	NOUN
bionys-568	184	33	.	.	PUNCT
bionys-568	185	1	in	in	ADP
bionys-568	185	2	addition	addition	NOUN
bionys-568	185	3	,	,	PUNCT
bionys-568	185	4	the	the	DET
bionys-568	185	5	g	g	PROPN
bionys-568	185	6	allele	allele	NOUN
bionys-568	185	7	of	of	ADP
bionys-568	185	8	this	this	DET
bionys-568	185	9	snp	snp	NOUN
bionys-568	185	10	showed	show	VERB
bionys-568	185	11	a	a	DET
bionys-568	185	12	positive	positive	ADJ
bionys-568	185	13	association	association	NOUN
bionys-568	185	14	with	with	ADP
bionys-568	185	15	obesity	obesity	NOUN
bionys-568	185	16	(	(	PUNCT
bionys-568	185	17	moon	moon	NOUN
bionys-568	185	18	et	et	PROPN
bionys-568	185	19	al	al	PROPN
bionys-568	185	20	.	.	PROPN
bionys-568	185	21	,	,	PUNCT
bionys-568	185	22	2013	2013	NUM
bionys-568	185	23	)	)	PUNCT
bionys-568	185	24	.	.	PUNCT
bionys-568	186	1	there	there	PRON
bionys-568	186	2	is	be	VERB
bionys-568	186	3	a	a	DET
bionys-568	186	4	relationship	relationship	NOUN
bionys-568	186	5	between	between	ADP
bionys-568	186	6	elevated	elevated	ADJ
bionys-568	186	7	liver	liver	NOUN
bionys-568	186	8	enzymes	enzyme	NOUN
bionys-568	186	9	alt	alt	ADJ
bionys-568	186	10	,	,	PUNCT
bionys-568	186	11	liver	liver	NOUN
bionys-568	186	12	cells	cell	NOUN
bionys-568	186	13	damage	damage	NOUN
bionys-568	186	14	,	,	PUNCT
bionys-568	186	15	and	and	CCONJ
bionys-568	186	16	hsd11b1	hsd11b1	VERB
bionys-568	186	17	polymorphisms	polymorphism	NOUN
bionys-568	186	18	(	(	PUNCT
bionys-568	186	19	rs12086634	rs12086634	PROPN
bionys-568	186	20	)	)	PUNCT
bionys-568	186	21	in	in	ADP
bionys-568	186	22	patients	patient	NOUN
bionys-568	186	23	suffering	suffer	VERB
bionys-568	186	24	from	from	ADP
bionys-568	186	25	nafld	nafld	ADJ
bionys-568	186	26	(	(	PUNCT
bionys-568	186	27	devang	devang	PROPN
bionys-568	186	28	et	et	PROPN
bionys-568	186	29	al	al	PROPN
bionys-568	186	30	.	.	PROPN
bionys-568	186	31	,	,	PUNCT
bionys-568	186	32	2017	2017	NUM
bionys-568	186	33	)	)	PUNCT
bionys-568	186	34	.	.	PUNCT
bionys-568	187	1	also	also	ADV
bionys-568	187	2	,	,	PUNCT
bionys-568	187	3	there	there	PRON
bionys-568	187	4	is	be	VERB
bionys-568	187	5	an	an	DET
bionys-568	187	6	association	association	NOUN
bionys-568	187	7	between	between	ADP
bionys-568	187	8	the	the	DET
bionys-568	187	9	t	t	PROPN
bionys-568	187	10	/	/	SYM
bionys-568	187	11	g	g	NOUN
bionys-568	187	12	genetic	genetic	ADJ
bionys-568	187	13	polymorphism	polymorphism	NOUN
bionys-568	187	14	biologica	biologica	PROPN
bionys-568	187	15	nyssana	nyssana	PROPN
bionys-568	188	1	●	●	PUNCT
bionys-568	188	2	16	16	NUM
bionys-568	188	3	(	(	PUNCT
bionys-568	188	4	1	1	NUM
bionys-568	188	5	)	)	PUNCT
bionys-568	188	6	june	june	PROPN
bionys-568	188	7	2025	2025	NUM
bionys-568	188	8	:	:	PUNCT
bionys-568	188	9	287	287	NUM
bionys-568	188	10	-	-	SYM
bionys-568	188	11	296	296	NUM
bionys-568	188	12	al	al	PROPN
bionys-568	188	13	-	-	PUNCT
bionys-568	188	14	khaykanee	khaykanee	PROPN
bionys-568	188	15	et	et	PROPN
bionys-568	188	16	al	al	PROPN
bionys-568	188	17	.	.	PUNCT
bionys-568	189	1	●	●	PUNCT
bionys-568	189	2	role	role	NOUN
bionys-568	189	3	of	of	ADP
bionys-568	189	4	11β	11β	PROPN
bionys-568	189	5	-	-	PUNCT
bionys-568	189	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	189	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	189	8	gene	gene	NOUN
bionys-568	189	9	polymorphisms	polymorphism	NOUN
bionys-568	189	10	rs846910	rs846910	NOUN
bionys-568	189	11	and	and	CCONJ
bionys-568	189	12	rs12086634	rs12086634	PROPN
bionys-568	189	13	in	in	ADP
bionys-568	189	14	the	the	DET
bionys-568	189	15	etiology	etiology	NOUN
bionys-568	189	16	of	of	ADP
bionys-568	189	17	hepatocellular	hepatocellular	ADJ
bionys-568	189	18	carcinoma	carcinoma	NOUN
bionys-568	189	19	table	table	NOUN
bionys-568	189	20	4	4	NUM
bionys-568	189	21	.	.	PUNCT
bionys-568	189	22	observed	observe	VERB
bionys-568	189	23	vs.	vs.	ADP
bionys-568	189	24	expected	expect	VERB
bionys-568	189	25	genotypic	genotypic	ADJ
bionys-568	189	26	frequencies	frequency	NOUN
bionys-568	189	27	and	and	CCONJ
bionys-568	189	28	hardy	hardy	ADJ
bionys-568	189	29	-	-	PUNCT
bionys-568	189	30	weinberg	weinberg	NOUN
bionys-568	189	31	equilibrium	equilibrium	NOUN
bionys-568	189	32	analysis	analysis	NOUN
bionys-568	189	33	for	for	ADP
bionys-568	189	34	11β	11β	NOUN
bionys-568	189	35	-	-	PUNCT
bionys-568	189	36	hsd1	hsd1	ADJ
bionys-568	189	37	rs846910	rs846910	NOUN
bionys-568	189	38	and	and	CCONJ
bionys-568	189	39	rs12086634	rs12086634	PROPN
bionys-568	189	40	polymorphisms	polymorphism	NOUN
bionys-568	189	41	observed	observe	VERB
bionys-568	189	42	expected	expect	VERB
bionys-568	189	43	χ2	χ2	PROPN
bionys-568	189	44	p	p	PROPN
bionys-568	189	45	rs12086634	rs12086634	PROPN
bionys-568	189	46	hcc	hcc	PROPN
bionys-568	189	47	(	(	PUNCT
bionys-568	189	48	n=50	n=50	ADJ
bionys-568	189	49	)	)	PUNCT
bionys-568	189	50	gg	gg	NOUN
bionys-568	189	51	8	8	NUM
bionys-568	189	52	12	12	NUM
bionys-568	189	53	0.271	0.271	NUM
bionys-568	189	54	0.018*tg	0.018*tg	NUM
bionys-568	189	55	40	40	NUM
bionys-568	189	56	83	83	NUM
bionys-568	189	57	tt	tt	PROPN
bionys-568	189	58	2	2	NUM
bionys-568	189	59	5	5	NUM
bionys-568	189	60	hbv	hbv	NOUN
bionys-568	189	61	(	(	PUNCT
bionys-568	189	62	n=50	n=50	ADJ
bionys-568	189	63	)	)	PUNCT
bionys-568	189	64	gg	gg	NOUN
bionys-568	189	65	9	9	NUM
bionys-568	189	66	10	10	NUM
bionys-568	189	67	1.69	1.69	NUM
bionys-568	189	68	0.184tg	0.184tg	NOUN
bionys-568	189	69	36	36	NUM
bionys-568	189	70	34	34	NUM
bionys-568	189	71	tt	tt	PROPN
bionys-568	189	72	5	5	NUM
bionys-568	189	73	6	6	NUM
bionys-568	189	74	control	control	NOUN
bionys-568	189	75	(	(	PUNCT
bionys-568	189	76	n=50	n=50	ADJ
bionys-568	189	77	)	)	PUNCT
bionys-568	189	78	gg	gg	NOUN
bionys-568	189	79	4	4	NUM
bionys-568	189	80	5	5	NUM
bionys-568	189	81	3.87	3.87	NUM
bionys-568	189	82	0.325tg	0.325tg	NOUN
bionys-568	189	83	5	5	NUM
bionys-568	189	84	7	7	NUM
bionys-568	189	85	tt	tt	PROPN
bionys-568	189	86	41	41	NUM
bionys-568	189	87	38	38	NUM
bionys-568	189	88	rs846910	rs846910	NOUN
bionys-568	189	89	hcc	hcc	PROPN
bionys-568	189	90	(	(	PUNCT
bionys-568	189	91	n=50	n=50	ADJ
bionys-568	189	92	)	)	PUNCT
bionys-568	189	93	aa	aa	NOUN
bionys-568	189	94	22	22	NUM
bionys-568	189	95	21	21	NUM
bionys-568	189	96	0.214	0.214	NUM
bionys-568	189	97	0.015	0.015	NUM
bionys-568	189	98	ga	ga	NOUN
bionys-568	189	99	28	28	NUM
bionys-568	189	100	29	29	NUM
bionys-568	189	101	hbv	hbv	NOUN
bionys-568	189	102	(	(	PUNCT
bionys-568	189	103	n=50	n=50	ADJ
bionys-568	189	104	)	)	PUNCT
bionys-568	189	105	aa	aa	NOUN
bionys-568	189	106	24	24	NUM
bionys-568	189	107	23	23	NUM
bionys-568	189	108	4.22	4.22	NUM
bionys-568	189	109	0.251	0.251	NUM
bionys-568	189	110	ga	ga	PROPN
bionys-568	189	111	26	26	NUM
bionys-568	189	112	27	27	NUM
bionys-568	189	113	control	control	NOUN
bionys-568	189	114	(	(	PUNCT
bionys-568	189	115	n=50	n=50	ADJ
bionys-568	189	116	)	)	PUNCT
bionys-568	189	117	aa	aa	NOUN
bionys-568	189	118	46	46	NUM
bionys-568	189	119	44	44	NUM
bionys-568	189	120	6.32	6.32	NUM
bionys-568	189	121	0.536	0.536	NUM
bionys-568	189	122	ga	ga	NOUN
bionys-568	189	123	4	4	NUM
bionys-568	189	124	6	6	NUM
bionys-568	189	125	*	*	PUNCT
bionys-568	189	126	statistically	statistically	ADV
bionys-568	189	127	significant	significant	ADJ
bionys-568	189	128	at	at	ADP
bionys-568	189	129	p≤0.05	p≤0.05	NOUN
bionys-568	189	130	294	294	NUM
bionys-568	189	131	in	in	ADP
bionys-568	189	132	hsd11b1	hsd11b1	ADJ
bionys-568	189	133	rs12086634	rs12086634	PROPN
bionys-568	189	134	and	and	CCONJ
bionys-568	189	135	increased	increase	VERB
bionys-568	189	136	visceral	visceral	ADJ
bionys-568	189	137	obesity	obesity	NOUN
bionys-568	189	138	as	as	ADP
bionys-568	189	139	a	a	DET
bionys-568	189	140	result	result	NOUN
bionys-568	189	141	of	of	ADP
bionys-568	189	142	increased	increase	VERB
bionys-568	189	143	hsd11b1	hsd11b1	NOUN
bionys-568	189	144	activity	activity	NOUN
bionys-568	189	145	(	(	PUNCT
bionys-568	189	146	gambineri	gambineri	NOUN
bionys-568	189	147	et	et	PROPN
bionys-568	189	148	al	al	PROPN
bionys-568	189	149	.	.	PROPN
bionys-568	189	150	,	,	PUNCT
bionys-568	189	151	2011	2011	NUM
bionys-568	189	152	)	)	PUNCT
bionys-568	189	153	.	.	PUNCT
bionys-568	190	1	11β	11β	NOUN
bionys-568	190	2	-	-	PUNCT
bionys-568	190	3	hsd1	hsd1	PROPN
bionys-568	190	4	,	,	PUNCT
bionys-568	190	5	containing	contain	VERB
bionys-568	190	6	the	the	DET
bionys-568	190	7	two	two	NUM
bionys-568	190	8	snps	snps	PROPN
bionys-568	190	9	rs846910	rs846910	NOUN
bionys-568	190	10	(	(	PUNCT
bionys-568	190	11	a	a	X
bionys-568	190	12	)	)	PUNCT
bionys-568	190	13	and	and	CCONJ
bionys-568	190	14	rs12086634	rs12086634	PROPN
bionys-568	190	15	(	(	PUNCT
bionys-568	190	16	t	t	PROPN
bionys-568	190	17	)	)	PUNCT
bionys-568	190	18	,	,	PUNCT
bionys-568	190	19	results	result	NOUN
bionys-568	190	20	in	in	ADP
bionys-568	190	21	enhanced	enhanced	ADJ
bionys-568	190	22	11β	11β	NOUN
bionys-568	190	23	-	-	PUNCT
bionys-568	190	24	hsd1	hsd1	NOUN
bionys-568	190	25	expression	expression	NOUN
bionys-568	190	26	and	and	CCONJ
bionys-568	190	27	activity	activity	NOUN
bionys-568	190	28	,	,	PUNCT
bionys-568	190	29	which	which	PRON
bionys-568	190	30	supports	support	VERB
bionys-568	190	31	the	the	DET
bionys-568	190	32	development	development	NOUN
bionys-568	190	33	of	of	ADP
bionys-568	190	34	metabolic	metabolic	NOUN
bionys-568	190	35	disorders	disorder	NOUN
bionys-568	190	36	(	(	PUNCT
bionys-568	190	37	gambineri	gambineri	PROPN
bionys-568	190	38	et	et	PROPN
bionys-568	190	39	al	al	PROPN
bionys-568	190	40	.	.	PROPN
bionys-568	190	41	,	,	PUNCT
bionys-568	190	42	2011	2011	NUM
bionys-568	190	43	)	)	PUNCT
bionys-568	190	44	.	.	PUNCT
bionys-568	191	1	studies	study	NOUN
bionys-568	191	2	on	on	ADP
bionys-568	191	3	the	the	DET
bionys-568	191	4	association	association	NOUN
bionys-568	191	5	of	of	ADP
bionys-568	191	6	snps	snps	PROPN
bionys-568	191	7	rs846910	rs846910	PROPN
bionys-568	191	8	and	and	CCONJ
bionys-568	191	9	rs12086634	rs12086634	PROPN
bionys-568	191	10	with	with	ADP
bionys-568	191	11	liver	liver	NOUN
bionys-568	191	12	disorders	disorder	NOUN
bionys-568	191	13	have	have	AUX
bionys-568	191	14	not	not	PART
bionys-568	191	15	yet	yet	ADV
bionys-568	191	16	been	be	AUX
bionys-568	191	17	conducted	conduct	VERB
bionys-568	191	18	,	,	PUNCT
bionys-568	191	19	despite	despite	SCONJ
bionys-568	191	20	the	the	DET
bionys-568	191	21	fact	fact	NOUN
bionys-568	191	22	that	that	SCONJ
bionys-568	191	23	there	there	PRON
bionys-568	191	24	are	be	VERB
bionys-568	191	25	several	several	ADJ
bionys-568	191	26	studies	study	NOUN
bionys-568	191	27	and	and	CCONJ
bionys-568	191	28	discoveries	discovery	NOUN
bionys-568	191	29	on	on	ADP
bionys-568	191	30	these	these	DET
bionys-568	191	31	snps	snps	NOUN
bionys-568	191	32	.	.	PUNCT
bionys-568	192	1	to	to	PART
bionys-568	192	2	confirm	confirm	VERB
bionys-568	192	3	the	the	DET
bionys-568	192	4	correlations	correlation	NOUN
bionys-568	192	5	found	find	VERB
bionys-568	192	6	in	in	ADP
bionys-568	192	7	this	this	DET
bionys-568	192	8	study	study	NOUN
bionys-568	192	9	and	and	CCONJ
bionys-568	192	10	clarify	clarify	VERB
bionys-568	192	11	the	the	DET
bionys-568	192	12	biological	biological	ADJ
bionys-568	192	13	processes	process	NOUN
bionys-568	192	14	behind	behind	ADP
bionys-568	192	15	these	these	DET
bionys-568	192	16	genetic	genetic	ADJ
bionys-568	192	17	predispositions	predisposition	NOUN
bionys-568	192	18	,	,	PUNCT
bionys-568	192	19	more	more	ADJ
bionys-568	192	20	research	research	NOUN
bionys-568	192	21	is	be	AUX
bionys-568	192	22	required	require	VERB
bionys-568	192	23	.	.	PUNCT
bionys-568	193	1	conclusion	conclusion	NOUN
bionys-568	193	2	in	in	ADP
bionys-568	193	3	conclusion	conclusion	NOUN
bionys-568	193	4	,	,	PUNCT
bionys-568	193	5	the	the	DET
bionys-568	193	6	study	study	NOUN
bionys-568	193	7	provides	provide	VERB
bionys-568	193	8	clear	clear	ADJ
bionys-568	193	9	evidence	evidence	NOUN
bionys-568	193	10	about	about	ADP
bionys-568	193	11	the	the	DET
bionys-568	193	12	relationship	relationship	NOUN
bionys-568	193	13	between	between	ADP
bionys-568	193	14	genetic	genetic	ADJ
bionys-568	193	15	polymorphisms	polymorphism	NOUN
bionys-568	193	16	in	in	ADP
bionys-568	193	17	rs12086634	rs12086634	PROPN
bionys-568	193	18	and	and	CCONJ
bionys-568	193	19	rs846910	rs846910	NOUN
bionys-568	193	20	within	within	ADP
bionys-568	193	21	the	the	DET
bionys-568	193	22	11β	11β	NUM
bionys-568	193	23	-	-	PUNCT
bionys-568	193	24	hsd1	hsd1	NOUN
bionys-568	193	25	gene	gene	NOUN
bionys-568	193	26	and	and	CCONJ
bionys-568	193	27	the	the	DET
bionys-568	193	28	possibility	possibility	NOUN
bionys-568	193	29	of	of	ADP
bionys-568	193	30	developing	develop	VERB
bionys-568	193	31	hepatocellular	hepatocellular	ADJ
bionys-568	193	32	carcinoma	carcinoma	NOUN
bionys-568	193	33	.	.	PUNCT
bionys-568	194	1	in	in	ADP
bionys-568	194	2	the	the	DET
bionys-568	194	3	case	case	NOUN
bionys-568	194	4	of	of	ADP
bionys-568	194	5	people	people	NOUN
bionys-568	194	6	infected	infect	VERB
bionys-568	194	7	with	with	ADP
bionys-568	194	8	the	the	DET
bionys-568	194	9	hepatitis	hepatitis	PROPN
bionys-568	194	10	b	b	PROPN
bionys-568	194	11	virus	virus	NOUN
bionys-568	194	12	,	,	PUNCT
bionys-568	194	13	as	as	SCONJ
bionys-568	194	14	the	the	DET
bionys-568	194	15	g	g	PROPN
bionys-568	194	16	allele	allele	NOUN
bionys-568	194	17	of	of	ADP
bionys-568	194	18	rs12086634	rs12086634	PROPN
bionys-568	194	19	was	be	AUX
bionys-568	194	20	found	find	VERB
bionys-568	194	21	to	to	PART
bionys-568	194	22	be	be	AUX
bionys-568	194	23	more	more	ADV
bionys-568	194	24	prevalent	prevalent	ADJ
bionys-568	194	25	in	in	ADP
bionys-568	194	26	the	the	DET
bionys-568	194	27	hepatocellular	hepatocellular	ADJ
bionys-568	194	28	carcinoma	carcinoma	NOUN
bionys-568	194	29	group	group	NOUN
bionys-568	194	30	and	and	CCONJ
bionys-568	194	31	the	the	DET
bionys-568	194	32	hepatitis	hepatitis	PROPN
bionys-568	194	33	b	b	PROPN
bionys-568	194	34	virus	virus	NOUN
bionys-568	194	35	group	group	NOUN
bionys-568	194	36	,	,	PUNCT
bionys-568	194	37	it	it	PRON
bionys-568	194	38	is	be	AUX
bionys-568	194	39	considered	consider	VERB
bionys-568	194	40	a	a	DET
bionys-568	194	41	risk	risk	NOUN
bionys-568	194	42	factor	factor	NOUN
bionys-568	194	43	for	for	ADP
bionys-568	194	44	cancer	cancer	NOUN
bionys-568	194	45	,	,	PUNCT
bionys-568	194	46	while	while	SCONJ
bionys-568	194	47	the	the	DET
bionys-568	194	48	t	t	PROPN
bionys-568	194	49	allele	allele	NOUN
bionys-568	194	50	was	be	AUX
bionys-568	194	51	found	find	VERB
bionys-568	194	52	to	to	PART
bionys-568	194	53	be	be	AUX
bionys-568	194	54	protective	protective	ADJ
bionys-568	194	55	.	.	PUNCT
bionys-568	195	1	for	for	ADP
bionys-568	195	2	rs846910	rs846910	NOUN
bionys-568	195	3	,	,	PUNCT
bionys-568	195	4	ga	ga	PROPN
bionys-568	195	5	was	be	AUX
bionys-568	195	6	the	the	DET
bionys-568	195	7	most	most	ADV
bionys-568	195	8	common	common	ADJ
bionys-568	195	9	genotype	genotype	NOUN
bionys-568	195	10	in	in	ADP
bionys-568	195	11	both	both	CCONJ
bionys-568	195	12	the	the	DET
bionys-568	195	13	liver	liver	NOUN
bionys-568	195	14	cancer	cancer	NOUN
bionys-568	195	15	group	group	NOUN
bionys-568	195	16	and	and	CCONJ
bionys-568	195	17	the	the	DET
bionys-568	195	18	hepatitis	hepatitis	PROPN
bionys-568	195	19	b	b	PROPN
bionys-568	195	20	virus	virus	NOUN
bionys-568	195	21	group	group	NOUN
bionys-568	195	22	.	.	PUNCT
bionys-568	196	1	since	since	SCONJ
bionys-568	196	2	the	the	DET
bionys-568	196	3	gg	gg	NOUN
bionys-568	196	4	genotype	genotype	NOUN
bionys-568	196	5	was	be	AUX
bionys-568	196	6	predominantly	predominantly	ADV
bionys-568	196	7	found	find	VERB
bionys-568	196	8	in	in	ADP
bionys-568	196	9	the	the	DET
bionys-568	196	10	control	control	NOUN
bionys-568	196	11	group	group	NOUN
bionys-568	196	12	,	,	PUNCT
bionys-568	196	13	this	this	PRON
bionys-568	196	14	confirms	confirm	VERB
bionys-568	196	15	that	that	SCONJ
bionys-568	196	16	the	the	DET
bionys-568	196	17	a	a	DET
bionys-568	196	18	allele	allele	NOUN
bionys-568	196	19	is	be	AUX
bionys-568	196	20	associated	associate	VERB
bionys-568	196	21	with	with	ADP
bionys-568	196	22	the	the	DET
bionys-568	196	23	risk	risk	NOUN
bionys-568	196	24	of	of	ADP
bionys-568	196	25	liver	liver	NOUN
bionys-568	196	26	cancer	cancer	NOUN
bionys-568	196	27	in	in	ADP
bionys-568	196	28	people	people	NOUN
bionys-568	196	29	carrying	carry	VERB
bionys-568	196	30	this	this	DET
bionys-568	196	31	allele	allele	NOUN
bionys-568	196	32	.	.	PUNCT
bionys-568	197	1	these	these	DET
bionys-568	197	2	genetic	genetic	ADJ
bionys-568	197	3	variations	variation	NOUN
bionys-568	197	4	are	be	AUX
bionys-568	197	5	considered	consider	VERB
bionys-568	197	6	indicators	indicator	NOUN
bionys-568	197	7	of	of	ADP
bionys-568	197	8	the	the	DET
bionys-568	197	9	risk	risk	NOUN
bionys-568	197	10	of	of	ADP
bionys-568	197	11	liver	liver	NOUN
bionys-568	197	12	cancer	cancer	NOUN
bionys-568	197	13	.	.	PUNCT
bionys-568	198	1	references	reference	NOUN
bionys-568	198	2	akinyemiju	akinyemiju	PROPN
bionys-568	198	3	,	,	PUNCT
bionys-568	198	4	t.	t.	PROPN
bionys-568	198	5	,	,	PUNCT
bionys-568	198	6	abera	abera	NOUN
bionys-568	198	7	,	,	PUNCT
bionys-568	198	8	s.	s.	PROPN
bionys-568	198	9	,	,	PUNCT
bionys-568	198	10	ahmed	ahmed	PROPN
bionys-568	198	11	,	,	PUNCT
bionys-568	198	12	m.	m.	NOUN
bionys-568	198	13	,	,	PUNCT
bionys-568	198	14	alam	alam	PROPN
bionys-568	198	15	,	,	PUNCT
bionys-568	198	16	n.	n.	PROPN
bionys-568	198	17	,	,	PUNCT
bionys-568	198	18	alemayohu	alemayohu	PROPN
bionys-568	198	19	,	,	PUNCT
bionys-568	198	20	m.a	m.a	PROPN
bionys-568	198	21	.	.	PROPN
bionys-568	198	22	,	,	PUNCT
bionys-568	198	23	allen	allen	PROPN
bionys-568	198	24	,	,	PUNCT
bionys-568	198	25	c.	c.	PROPN
bionys-568	198	26	,	,	PUNCT
bionys-568	198	27	...	...	PUNCT
bionys-568	198	28	&	&	CCONJ
bionys-568	198	29	global	global	ADJ
bionys-568	198	30	burden	burden	NOUN
bionys-568	198	31	of	of	ADP
bionys-568	198	32	disease	disease	NOUN
bionys-568	198	33	liver	liver	NOUN
bionys-568	198	34	cancer	cancer	NOUN
bionys-568	198	35	collaboration	collaboration	NOUN
bionys-568	198	36	.	.	PUNCT
bionys-568	199	1	(	(	PUNCT
bionys-568	199	2	2017	2017	NUM
bionys-568	199	3	)	)	PUNCT
bionys-568	199	4	.	.	PUNCT
bionys-568	200	1	the	the	DET
bionys-568	200	2	burden	burden	NOUN
bionys-568	200	3	of	of	ADP
bionys-568	200	4	primary	primary	ADJ
bionys-568	200	5	liver	liver	NOUN
bionys-568	200	6	cancer	cancer	NOUN
bionys-568	200	7	and	and	CCONJ
bionys-568	200	8	underlying	underlying	ADJ
bionys-568	200	9	etiologies	etiology	NOUN
bionys-568	200	10	from	from	ADP
bionys-568	200	11	1990	1990	NUM
bionys-568	200	12	to	to	ADP
bionys-568	200	13	2015	2015	NUM
bionys-568	200	14	at	at	ADP
bionys-568	200	15	the	the	DET
bionys-568	200	16	global	global	ADJ
bionys-568	200	17	,	,	PUNCT
bionys-568	200	18	regional	regional	ADJ
bionys-568	200	19	,	,	PUNCT
bionys-568	200	20	and	and	CCONJ
bionys-568	200	21	national	national	ADJ
bionys-568	200	22	level	level	NOUN
bionys-568	200	23	:	:	PUNCT
bionys-568	200	24	results	result	NOUN
bionys-568	200	25	from	from	ADP
bionys-568	200	26	the	the	DET
bionys-568	200	27	global	global	ADJ
bionys-568	200	28	burden	burden	NOUN
bionys-568	200	29	of	of	ADP
bionys-568	200	30	disease	disease	NOUN
bionys-568	200	31	study	study	NOUN
bionys-568	200	32	2015	2015	NUM
bionys-568	200	33	.	.	PUNCT
bionys-568	201	1	jama	jama	PROPN
bionys-568	201	2	oncology	oncology	NOUN
bionys-568	201	3	,	,	PUNCT
bionys-568	201	4	3(12	3(12	NUM
bionys-568	201	5	)	)	PUNCT
bionys-568	201	6	,	,	PUNCT
bionys-568	201	7	1683	1683	NUM
bionys-568	201	8	-	-	SYM
bionys-568	201	9	1691	1691	NUM
bionys-568	201	10	.	.	PUNCT
bionys-568	202	1	doi	doi	NOUN
bionys-568	202	2	:	:	PUNCT
bionys-568	202	3	10.1001/	10.1001/	NUM
bionys-568	202	4	jamaoncol.2017.3055	jamaoncol.2017.3055	NOUN
bionys-568	202	5	.	.	PUNCT
bionys-568	203	1	al	al	PROPN
bionys-568	203	2	-	-	PUNCT
bionys-568	203	3	khaykanee	khaykanee	PROPN
bionys-568	203	4	,	,	PUNCT
bionys-568	203	5	a.m.	a.m.	ADV
bionys-568	203	6	,	,	PUNCT
bionys-568	203	7	abdel	abdel	PROPN
bionys-568	203	8	-	-	PUNCT
bionys-568	203	9	rahman	rahman	PROPN
bionys-568	203	10	,	,	PUNCT
bionys-568	203	11	a.a	a.a	PROPN
bionys-568	203	12	.	.	PROPN
bionys-568	203	13	,	,	PUNCT
bionys-568	203	14	essa	essa	PROPN
bionys-568	203	15	,	,	PUNCT
bionys-568	203	16	a.	a.	PROPN
bionys-568	203	17	,	,	PUNCT
bionys-568	203	18	gadallah	gadallah	PROPN
bionys-568	203	19	,	,	PUNCT
bionys-568	203	20	a.n.a.a	a.n.a.a	PROPN
bionys-568	203	21	.	.	PROPN
bionys-568	203	22	,	,	PUNCT
bionys-568	203	23	ali	ali	PROPN
bionys-568	203	24	,	,	PUNCT
bionys-568	203	25	b.h	b.h	PROPN
bionys-568	203	26	.	.	PROPN
bionys-568	203	27	,	,	PUNCT
bionys-568	203	28	al	al	PROPN
bionys-568	203	29	-	-	PUNCT
bionys-568	203	30	aqar	aqar	VERB
bionys-568	203	31	,	,	PUNCT
bionys-568	203	32	a.a	a.a	PROPN
bionys-568	203	33	.	.	PROPN
bionys-568	203	34	,	,	PUNCT
bionys-568	203	35	...	...	PUNCT
bionys-568	203	36	&	&	CCONJ
bionys-568	203	37	shehab	shehab	PROPN
bionys-568	203	38	-	-	PUNCT
bionys-568	203	39	eldeen	eldeen	PROPN
bionys-568	203	40	,	,	PUNCT
bionys-568	203	41	s.	s.	PROPN
bionys-568	203	42	(	(	PUNCT
bionys-568	203	43	2021	2021	NUM
bionys-568	203	44	)	)	PUNCT
bionys-568	203	45	.	.	PUNCT
bionys-568	204	1	genetic	genetic	ADJ
bionys-568	204	2	polymorphism	polymorphism	NOUN
bionys-568	204	3	of	of	ADP
bionys-568	204	4	fibroblast	fibroblast	ADJ
bionys-568	204	5	growth	growth	NOUN
bionys-568	204	6	factor	factor	NOUN
bionys-568	204	7	receptor	receptor	NOUN
bionys-568	204	8	2	2	NUM
bionys-568	204	9	and	and	CCONJ
bionys-568	204	10	trinucleotide	trinucleotide	ADV
bionys-568	204	11	repeat	repeat	NOUN
bionys-568	204	12	-	-	PUNCT
bionys-568	204	13	containing	contain	VERB
bionys-568	204	14	9	9	NUM
bionys-568	204	15	influence	influence	NOUN
bionys-568	204	16	the	the	DET
bionys-568	204	17	susceptibility	susceptibility	NOUN
bionys-568	204	18	to	to	ADP
bionys-568	204	19	hcv	hcv	VERB
bionys-568	204	20	-	-	PUNCT
bionys-568	204	21	induced	induce	VERB
bionys-568	204	22	hepatocellular	hepatocellular	ADJ
bionys-568	204	23	carcinoma	carcinoma	NOUN
bionys-568	204	24	.	.	PUNCT
bionys-568	205	1	clinics	clinic	NOUN
bionys-568	205	2	and	and	CCONJ
bionys-568	205	3	research	research	NOUN
bionys-568	205	4	in	in	ADP
bionys-568	205	5	hepatology	hepatology	NOUN
bionys-568	205	6	and	and	CCONJ
bionys-568	205	7	gastroenterology	gastroenterology	NOUN
bionys-568	205	8	,	,	PUNCT
bionys-568	205	9	45(6	45(6	NUM
bionys-568	205	10	)	)	PUNCT
bionys-568	205	11	,	,	PUNCT
bionys-568	205	12	101636.‏	101636.‏	PROPN
bionys-568	205	13	assefa	assefa	PROPN
bionys-568	205	14	,	,	PUNCT
bionys-568	205	15	a.	a.	NOUN
bionys-568	205	16	,	,	PUNCT
bionys-568	205	17	getie	getie	NOUN
bionys-568	205	18	,	,	PUNCT
bionys-568	205	19	m.	m.	NOUN
bionys-568	205	20	,	,	PUNCT
bionys-568	205	21	getie	getie	NOUN
bionys-568	205	22	,	,	PUNCT
bionys-568	205	23	b.	b.	PROPN
bionys-568	205	24	,	,	PUNCT
bionys-568	205	25	simeneh	simeneh	PROPN
bionys-568	205	26	,	,	PUNCT
bionys-568	205	27	t.	t.	PROPN
bionys-568	205	28	,	,	PUNCT
bionys-568	205	29	&	&	CCONJ
bionys-568	205	30	enkobahry	enkobahry	PROPN
bionys-568	205	31	,	,	PUNCT
bionys-568	205	32	a.	a.	NOUN
bionys-568	205	33	(	(	PUNCT
bionys-568	205	34	2024	2024	NUM
bionys-568	205	35	)	)	PUNCT
bionys-568	205	36	.	.	PUNCT
bionys-568	206	1	molecular	molecular	ADJ
bionys-568	206	2	epidemiology	epidemiology	NOUN
bionys-568	206	3	of	of	ADP
bionys-568	206	4	hepatitis	hepatitis	PROPN
bionys-568	206	5	b	b	PROPN
bionys-568	206	6	virus	virus	NOUN
bionys-568	206	7	(	(	PUNCT
bionys-568	206	8	hbv	hbv	NOUN
bionys-568	206	9	)	)	PUNCT
bionys-568	206	10	in	in	ADP
bionys-568	206	11	ethiopia	ethiopia	PROPN
bionys-568	206	12	:	:	PUNCT
bionys-568	206	13	a	a	DET
bionys-568	206	14	review	review	NOUN
bionys-568	206	15	article	article	NOUN
bionys-568	206	16	.	.	PUNCT
bionys-568	207	1	infection	infection	NOUN
bionys-568	207	2	,	,	PUNCT
bionys-568	207	3	genetics	genetic	NOUN
bionys-568	207	4	and	and	CCONJ
bionys-568	207	5	evolution	evolution	NOUN
bionys-568	207	6	,	,	PUNCT
bionys-568	207	7	122	122	NUM
bionys-568	207	8	,	,	PUNCT
bionys-568	207	9	.doi	.doi	PROPN
bionys-568	207	10	:	:	PUNCT
bionys-568	207	11	10.1016	10.1016	NUM
bionys-568	207	12	/	/	SYM
bionys-568	207	13	j.meegid.2024.105618	j.meegid.2024.105618	PROPN
bionys-568	207	14	‏.105618	‏.105618	X
bionys-568	207	15	aziz	aziz	PROPN
bionys-568	207	16	,	,	PUNCT
bionys-568	207	17	h.	h.	PROPN
bionys-568	207	18	,	,	PUNCT
bionys-568	207	19	raslan	raslan	NOUN
bionys-568	207	20	,	,	PUNCT
bionys-568	207	21	m.	m.	NOUN
bionys-568	207	22	,	,	PUNCT
bionys-568	207	23	el	el	PROPN
bionys-568	207	24	dahshan	dahshan	PROPN
bionys-568	207	25	,	,	PUNCT
bionys-568	207	26	d.	d.	PROPN
bionys-568	207	27	,	,	PUNCT
bionys-568	207	28	afify	afify	VERB
bionys-568	207	29	,	,	PUNCT
bionys-568	207	30	m.	m.	NOUN
bionys-568	207	31	,	,	PUNCT
bionys-568	207	32	hamimy	hamimy	PROPN
bionys-568	207	33	,	,	PUNCT
bionys-568	207	34	w.i	w.i	PROPN
bionys-568	207	35	.	.	PROPN
bionys-568	207	36	,	,	PUNCT
bionys-568	207	37	&	&	CCONJ
bionys-568	207	38	gouda	gouda	NOUN
bionys-568	207	39	,	,	PUNCT
bionys-568	207	40	w.	w.	NOUN
bionys-568	207	41	(	(	PUNCT
bionys-568	207	42	2023	2023	NUM
bionys-568	207	43	)	)	PUNCT
bionys-568	207	44	.	.	PUNCT
bionys-568	208	1	11β	11β	NOUN
bionys-568	208	2	hydroxysteroid	hydroxysteroid	VERB
bionys-568	208	3	dehydrogenase	dehydrogenase	NOUN
bionys-568	208	4	type	type	NOUN
bionys-568	208	5	1	1	NUM
bionys-568	208	6	gene	gene	NOUN
bionys-568	208	7	expression	expression	NOUN
bionys-568	208	8	in	in	ADP
bionys-568	208	9	obesity	obesity	NOUN
bionys-568	208	10	and	and	CCONJ
bionys-568	208	11	its	its	PRON
bionys-568	208	12	complications	complication	NOUN
bionys-568	208	13	.	.	PUNCT
bionys-568	209	1	egyptian	egyptian	ADJ
bionys-568	209	2	journal	journal	PROPN
bionys-568	209	3	of	of	ADP
bionys-568	209	4	chemistry	chemistry	NOUN
bionys-568	209	5	,	,	PUNCT
bionys-568	209	6	66(7	66(7	NUM
bionys-568	209	7	)	)	PUNCT
bionys-568	209	8	,	,	PUNCT
bionys-568	209	9	165	165	NUM
bionys-568	209	10	-	-	SYM
bionys-568	209	11	174	174	NUM
bionys-568	209	12	.	.	PUNCT
bionys-568	210	1	doi	doi	NOUN
bionys-568	210	2	:	:	PUNCT
bionys-568	210	3	10.21608	10.21608	NUM
bionys-568	210	4	/	/	SYM
bionys-568	210	5	ejchem.2022.157145.6819	ejchem.2022.157145.6819	NOUN
bionys-568	210	6	.	.	PUNCT
bionys-568	211	1	brown	brown	PROPN
bionys-568	211	2	,	,	PUNCT
bionys-568	211	3	z.j	z.j	PROPN
bionys-568	211	4	.	.	PROPN
bionys-568	211	5	,	,	PUNCT
bionys-568	211	6	tsilimigras	tsilimigras	PROPN
bionys-568	211	7	,	,	PUNCT
bionys-568	211	8	d.i	d.i	PROPN
bionys-568	211	9	.	.	PROPN
bionys-568	211	10	,	,	PUNCT
bionys-568	211	11	ruff	ruff	PROPN
bionys-568	211	12	,	,	PUNCT
bionys-568	211	13	s.m	s.m	PROPN
bionys-568	211	14	.	.	PROPN
bionys-568	211	15	,	,	PUNCT
bionys-568	211	16	mohseni	mohseni	NOUN
bionys-568	211	17	,	,	PUNCT
bionys-568	211	18	a.	a.	PROPN
bionys-568	211	19	,	,	PUNCT
bionys-568	211	20	kamel	kamel	PROPN
bionys-568	211	21	,	,	PUNCT
bionys-568	211	22	i.r	i.r	PROPN
bionys-568	211	23	.	.	PROPN
bionys-568	211	24	,	,	PUNCT
bionys-568	211	25	cloyd	cloyd	PROPN
bionys-568	211	26	,	,	PUNCT
bionys-568	211	27	j.m	j.m	PROPN
bionys-568	211	28	.	.	PROPN
bionys-568	211	29	,	,	PUNCT
bionys-568	211	30	&	&	CCONJ
bionys-568	211	31	pawlik	pawlik	PROPN
bionys-568	211	32	,	,	PUNCT
bionys-568	211	33	t.m	t.m	PROPN
bionys-568	211	34	.	.	PROPN
bionys-568	211	35	(	(	PUNCT
bionys-568	211	36	2023	2023	NUM
bionys-568	211	37	)	)	PUNCT
bionys-568	211	38	.	.	PUNCT
bionys-568	212	1	management	management	NOUN
bionys-568	212	2	of	of	ADP
bionys-568	212	3	hepatocellular	hepatocellular	ADJ
bionys-568	212	4	carcinoma	carcinoma	NOUN
bionys-568	212	5	:	:	PUNCT
bionys-568	212	6	a	a	DET
bionys-568	212	7	review	review	NOUN
bionys-568	212	8	.	.	PUNCT
bionys-568	213	1	jama	jama	PROPN
bionys-568	213	2	surgery	surgery	NOUN
bionys-568	213	3	,	,	PUNCT
bionys-568	213	4	158(4	158(4	NUM
bionys-568	213	5	)	)	PUNCT
bionys-568	213	6	,	,	PUNCT
bionys-568	213	7	410.doi	410.doi	PROPN
bionys-568	213	8	:	:	PUNCT
bionys-568	213	9	10.1001	10.1001	NUM
bionys-568	213	10	/	/	SYM
bionys-568	213	11	jamasurg.2022.7989	jamasurg.2022.7989	VERB
bionys-568	213	12	‏.420	‏.420	X
bionys-568	213	13	de	de	X
bionys-568	213	14	kloet	kloet	VERB
bionys-568	213	15	,	,	PUNCT
bionys-568	213	16	e.r	e.r	PROPN
bionys-568	213	17	.	.	PROPN
bionys-568	213	18	,	,	PUNCT
bionys-568	213	19	de	de	PROPN
bionys-568	213	20	kloet	kloet	NOUN
bionys-568	213	21	,	,	PUNCT
bionys-568	213	22	s.f	s.f	PROPN
bionys-568	213	23	.	.	PROPN
bionys-568	213	24	,	,	PUNCT
bionys-568	213	25	de	de	PROPN
bionys-568	213	26	kloet	kloet	NOUN
bionys-568	213	27	,	,	PUNCT
bionys-568	213	28	c.s	c.s	PROPN
bionys-568	213	29	.	.	PROPN
bionys-568	213	30	,	,	PUNCT
bionys-568	213	31	&	&	CCONJ
bionys-568	213	32	de	de	PROPN
bionys-568	213	33	kloet	kloet	PROPN
bionys-568	213	34	,	,	PUNCT
bionys-568	213	35	a.d	a.d	PROPN
bionys-568	213	36	.	.	PROPN
bionys-568	213	37	(	(	PUNCT
bionys-568	213	38	2019	2019	NUM
bionys-568	213	39	)	)	PUNCT
bionys-568	213	40	.	.	PUNCT
bionys-568	214	1	top‐down	top‐down	NUM
bionys-568	214	2	and	and	CCONJ
bionys-568	214	3	bottom‐up	bottom‐up	ADP
bionys-568	214	4	control	control	NOUN
bionys-568	214	5	of	of	ADP
bionys-568	214	6	stress‐coping	stress‐coping	PROPN
bionys-568	214	7	.	.	PUNCT
bionys-568	215	1	journal	journal	PROPN
bionys-568	215	2	of	of	ADP
bionys-568	215	3	neuroendocrinology	neuroendocrinology	NOUN
bionys-568	215	4	,	,	PUNCT
bionys-568	215	5	31(3	31(3	NUM
bionys-568	215	6	)	)	PUNCT
bionys-568	215	7	,	,	PUNCT
bionys-568	215	8	e12675	e12675	PROPN
bionys-568	215	9	.	.	PUNCT
bionys-568	215	10	doi	doi	NOUN
bionys-568	215	11	:	:	PUNCT
bionys-568	215	12	10.1111	10.1111	NUM
bionys-568	215	13	/	/	SYM
bionys-568	215	14	jne.12675	jne.12675	PROPN
bionys-568	215	15	.	.	PUNCT
bionys-568	216	1	devang	devang	PROPN
bionys-568	216	2	,	,	PUNCT
bionys-568	216	3	n.	n.	NOUN
bionys-568	216	4	,	,	PUNCT
bionys-568	216	5	satyamoorthy	satyamoorthy	ADJ
bionys-568	216	6	,	,	PUNCT
bionys-568	216	7	k.	k.	PROPN
bionys-568	216	8	,	,	PUNCT
bionys-568	216	9	rai	rai	PROPN
bionys-568	216	10	,	,	PUNCT
bionys-568	216	11	p.s	p.s	PROPN
bionys-568	216	12	.	.	PROPN
bionys-568	216	13	,	,	PUNCT
bionys-568	216	14	nandini	nandini	PROPN
bionys-568	216	15	,	,	PUNCT
bionys-568	216	16	m.	m.	NOUN
bionys-568	216	17	,	,	PUNCT
bionys-568	216	18	rao	rao	PROPN
bionys-568	216	19	,	,	PUNCT
bionys-568	216	20	s.	s.	PROPN
bionys-568	216	21	,	,	PUNCT
bionys-568	216	22	phani	phani	PROPN
bionys-568	216	23	,	,	PUNCT
bionys-568	216	24	n.m	n.m	PROPN
bionys-568	216	25	.	.	PROPN
bionys-568	216	26	,	,	PUNCT
bionys-568	216	27	&	&	CCONJ
bionys-568	216	28	adhikari	adhikari	PROPN
bionys-568	216	29	,	,	PUNCT
bionys-568	216	30	p.	p.	NOUN
bionys-568	216	31	(	(	PUNCT
bionys-568	216	32	2017	2017	NUM
bionys-568	216	33	)	)	PUNCT
bionys-568	216	34	.	.	PUNCT
bionys-568	217	1	association	association	NOUN
bionys-568	217	2	of	of	ADP
bionys-568	217	3	hsd11b1	hsd11b1	PROPN
bionys-568	217	4	gene	gene	NOUN
bionys-568	217	5	polymorphisms	polymorphism	NOUN
bionys-568	217	6	with	with	ADP
bionys-568	217	7	type	type	NOUN
bionys-568	217	8	2	2	NUM
bionys-568	217	9	diabetes	diabetes	NOUN
bionys-568	217	10	and	and	CCONJ
bionys-568	217	11	metabolic	metabolic	NOUN
bionys-568	217	12	syndrome	syndrome	NOUN
bionys-568	217	13	in	in	ADP
bionys-568	217	14	south	south	PROPN
bionys-568	217	15	indian	indian	ADJ
bionys-568	217	16	population	population	NOUN
bionys-568	217	17	.	.	PUNCT
bionys-568	218	1	diabetes	diabetes	NOUN
bionys-568	218	2	research	research	NOUN
bionys-568	218	3	and	and	CCONJ
bionys-568	218	4	clinical	clinical	ADJ
bionys-568	218	5	practice	practice	NOUN
bionys-568	218	6	,	,	PUNCT
bionys-568	218	7	131	131	NUM
bionys-568	218	8	,	,	PUNCT
bionys-568	218	9	142	142	NUM
bionys-568	218	10	-	-	SYM
bionys-568	218	11	148	148	NUM
bionys-568	218	12	.	.	PUNCT
bionys-568	219	1	doi	doi	NOUN
bionys-568	219	2	:	:	PUNCT
bionys-568	219	3	10.1016	10.1016	NUM
bionys-568	219	4	/	/	SYM
bionys-568	219	5	j.	j.	PROPN
bionys-568	219	6	diabres.2017.07.011	diabres.2017.07.011	PROPN
bionys-568	219	7	.	.	PUNCT
bionys-568	220	1	galle	galle	PROPN
bionys-568	220	2	,	,	PUNCT
bionys-568	220	3	p.r	p.r	PROPN
bionys-568	220	4	.	.	PROPN
bionys-568	220	5	,	,	PUNCT
bionys-568	220	6	forner	forner	NOUN
bionys-568	220	7	,	,	PUNCT
bionys-568	220	8	a.	a.	NOUN
bionys-568	220	9	,	,	PUNCT
bionys-568	220	10	llovet	llovet	NOUN
bionys-568	220	11	,	,	PUNCT
bionys-568	220	12	j.m	j.m	PROPN
bionys-568	220	13	.	.	PROPN
bionys-568	220	14	,	,	PUNCT
bionys-568	220	15	mazzaferro	mazzaferro	PROPN
bionys-568	220	16	,	,	PUNCT
bionys-568	220	17	v.	v.	PROPN
bionys-568	220	18	,	,	PUNCT
bionys-568	220	19	piscaglia	piscaglia	PROPN
bionys-568	220	20	,	,	PUNCT
bionys-568	220	21	f.	f.	PROPN
bionys-568	220	22	,	,	PUNCT
bionys-568	220	23	raoul	raoul	PROPN
bionys-568	220	24	,	,	PUNCT
bionys-568	220	25	j.l	j.l	PROPN
bionys-568	220	26	.	.	PROPN
bionys-568	220	27	,	,	PUNCT
bionys-568	220	28	schirmacher	schirmacher	ADP
bionys-568	220	29	,	,	PUNCT
bionys-568	220	30	p.	p.	NOUN
bionys-568	220	31	,	,	PUNCT
bionys-568	220	32	&	&	CCONJ
bionys-568	220	33	vilgrain	vilgrain	PROPN
bionys-568	220	34	,	,	PUNCT
bionys-568	220	35	v.	v.	PROPN
bionys-568	220	36	(	(	PUNCT
bionys-568	220	37	2018	2018	NUM
bionys-568	220	38	)	)	PUNCT
bionys-568	220	39	.	.	PUNCT
bionys-568	221	1	easl	easl	NOUN
bionys-568	221	2	clinical	clinical	ADJ
bionys-568	221	3	practice	practice	NOUN
bionys-568	221	4	guidelines	guideline	NOUN
bionys-568	221	5	:	:	PUNCT
bionys-568	221	6	management	management	NOUN
bionys-568	221	7	of	of	ADP
bionys-568	221	8	hepatocellular	hepatocellular	ADJ
bionys-568	221	9	carcinoma	carcinoma	NOUN
bionys-568	221	10	.	.	PUNCT
bionys-568	222	1	journal	journal	NOUN
bionys-568	222	2	of	of	ADP
bionys-568	222	3	hepatology	hepatology	NOUN
bionys-568	222	4	,	,	PUNCT
bionys-568	222	5	69(1	69(1	NUM
bionys-568	222	6	)	)	PUNCT
bionys-568	222	7	,	,	PUNCT
bionys-568	222	8	182	182	NUM
bionys-568	222	9	-	-	SYM
bionys-568	222	10	236.‏	236.‏	NUM
bionys-568	222	11	doi	doi	NOUN
bionys-568	222	12	:	:	PUNCT
bionys-568	222	13	10.1016	10.1016	NUM
bionys-568	222	14	/	/	SYM
bionys-568	222	15	j.jhep.2018.03.019	j.jhep.2018.03.019	PROPN
bionys-568	222	16	.	.	PUNCT
bionys-568	223	1	gambineri	gambineri	PROPN
bionys-568	223	2	,	,	PUNCT
bionys-568	223	3	a.	a.	NOUN
bionys-568	223	4	,	,	PUNCT
bionys-568	223	5	tomassoni	tomassoni	NOUN
bionys-568	223	6	,	,	PUNCT
bionys-568	223	7	f.	f.	PROPN
bionys-568	223	8	,	,	PUNCT
bionys-568	223	9	munarini	munarini	PROPN
bionys-568	223	10	,	,	PUNCT
bionys-568	223	11	a.	a.	NOUN
bionys-568	223	12	,	,	PUNCT
bionys-568	223	13	stimson	stimson	PROPN
bionys-568	223	14	,	,	PUNCT
bionys-568	223	15	r.h	r.h	PROPN
bionys-568	223	16	.	.	PROPN
bionys-568	223	17	,	,	PUNCT
bionys-568	223	18	mioni	mioni	PROPN
bionys-568	223	19	,	,	PUNCT
bionys-568	223	20	r.	r.	PROPN
bionys-568	223	21	,	,	PUNCT
bionys-568	223	22	pagotto	pagotto	NOUN
bionys-568	223	23	,	,	PUNCT
bionys-568	223	24	u.	u.	PROPN
bionys-568	223	25	,	,	PUNCT
bionys-568	223	26	chapman	chapman	PROPN
bionys-568	223	27	,	,	PUNCT
bionys-568	223	28	k.e	k.e	PROPN
bionys-568	223	29	.	.	PROPN
bionys-568	223	30	,	,	PUNCT
bionys-568	223	31	andrew	andrew	PROPN
bionys-568	223	32	,	,	PUNCT
bionys-568	223	33	r.	r.	PROPN
bionys-568	223	34	,	,	PUNCT
bionys-568	223	35	mantovani	mantovani	PROPN
bionys-568	223	36	,	,	PUNCT
bionys-568	223	37	v.	v.	PROPN
bionys-568	223	38	,	,	PUNCT
bionys-568	223	39	pasquali	pasquali	PROPN
bionys-568	223	40	,	,	PUNCT
bionys-568	223	41	r.	r.	PROPN
bionys-568	223	42	,	,	PUNCT
bionys-568	223	43	&	&	CCONJ
bionys-568	223	44	walker	walker	PROPN
bionys-568	223	45	,	,	PUNCT
bionys-568	223	46	b.r	b.r	PROPN
bionys-568	223	47	.	.	PROPN
bionys-568	223	48	(	(	PUNCT
bionys-568	223	49	2011	2011	NUM
bionys-568	223	50	)	)	PUNCT
bionys-568	223	51	.	.	PUNCT
bionys-568	224	1	a	a	DET
bionys-568	224	2	combination	combination	NOUN
bionys-568	224	3	of	of	ADP
bionys-568	224	4	polymorphisms	polymorphism	NOUN
bionys-568	224	5	in	in	ADP
bionys-568	224	6	hsd11b1	hsd11b1	NOUN
bionys-568	224	7	associates	associate	NOUN
bionys-568	224	8	with	with	ADP
bionys-568	224	9	in	in	ADP
bionys-568	224	10	vivo	vivo	ADJ
bionys-568	224	11	11β	11β	NOUN
bionys-568	224	12	-	-	PUNCT
bionys-568	224	13	hsd1	hsd1	NOUN
bionys-568	224	14	activity	activity	NOUN
bionys-568	224	15	and	and	CCONJ
bionys-568	224	16	metabolic	metabolic	NOUN
bionys-568	224	17	syndrome	syndrome	NOUN
bionys-568	224	18	in	in	ADP
bionys-568	224	19	women	woman	NOUN
bionys-568	224	20	with	with	ADP
bionys-568	224	21	and	and	CCONJ
bionys-568	224	22	without	without	ADP
bionys-568	224	23	polycystic	polycystic	ADJ
bionys-568	224	24	ovary	ovary	ADJ
bionys-568	224	25	syndrome	syndrome	NOUN
bionys-568	224	26	.	.	PUNCT
bionys-568	225	1	european	european	PROPN
bionys-568	225	2	journal	journal	PROPN
bionys-568	225	3	of	of	ADP
bionys-568	225	4	endocrinology	endocrinology	NOUN
bionys-568	225	5	,	,	PUNCT
bionys-568	225	6	165(2	165(2	NUM
bionys-568	225	7	)	)	PUNCT
bionys-568	225	8	,	,	PUNCT
bionys-568	225	9	283292	283292	NUM
bionys-568	225	10	.	.	PUNCT
bionys-568	226	1	doi	doi	NOUN
bionys-568	226	2	:	:	PUNCT
bionys-568	226	3	10.1530	10.1530	NUM
bionys-568	226	4	/	/	SYM
bionys-568	226	5	eje-11	eje-11	NOUN
bionys-568	226	6	-	-	PUNCT
bionys-568	226	7	0091	0091	NUM
bionys-568	226	8	.	.	PUNCT
bionys-568	227	1	jiang	jiang	PROPN
bionys-568	227	2	,	,	PUNCT
bionys-568	227	3	y.	y.	PROPN
bionys-568	227	4	,	,	PUNCT
bionys-568	227	5	han	han	PROPN
bionys-568	227	6	,	,	PUNCT
bionys-568	227	7	q.	q.	PROPN
bionys-568	227	8	,	,	PUNCT
bionys-568	227	9	zhao	zhao	PROPN
bionys-568	227	10	,	,	PUNCT
bionys-568	227	11	h.	h.	PROPN
bionys-568	227	12	,	,	PUNCT
bionys-568	227	13	&	&	CCONJ
bionys-568	227	14	zhang	zhang	PROPN
bionys-568	227	15	,	,	PUNCT
bionys-568	227	16	j.	j.	PROPN
bionys-568	227	17	(	(	PUNCT
bionys-568	227	18	2021	2021	NUM
bionys-568	227	19	)	)	PUNCT
bionys-568	227	20	.	.	PUNCT
bionys-568	228	1	the	the	DET
bionys-568	228	2	mechanisms	mechanism	NOUN
bionys-568	228	3	of	of	ADP
bionys-568	228	4	hbv	hbv	NOUN
bionys-568	228	5	-	-	PUNCT
bionys-568	228	6	induced	induce	VERB
bionys-568	228	7	hepatocellular	hepatocellular	ADJ
bionys-568	228	8	carcinoma	carcinoma	NOUN
bionys-568	228	9	.	.	PUNCT
bionys-568	229	1	journal	journal	NOUN
bionys-568	229	2	of	of	ADP
bionys-568	229	3	hepatocellular	hepatocellular	ADJ
bionys-568	229	4	carcinoma	carcinoma	NOUN
bionys-568	229	5	,	,	PUNCT
bionys-568	229	6	.doi	.doi	PROPN
bionys-568	229	7	:	:	PUNCT
bionys-568	229	8	10.2147	10.2147	NUM
bionys-568	229	9	/	/	SYM
bionys-568	229	10	jhc.s307962	jhc.s307962	NOUN
bionys-568	229	11	‏.435	‏.435	NOUN
bionys-568	229	12	-	-	PUNCT
bionys-568	229	13	450	450	NUM
bionys-568	229	14	,	,	PUNCT
bionys-568	229	15	8	8	NUM
bionys-568	229	16	kotelevtsev	kotelevtsev	NOUN
bionys-568	229	17	,	,	PUNCT
bionys-568	229	18	y.	y.	PROPN
bionys-568	229	19	,	,	PUNCT
bionys-568	229	20	holmes	holmes	PROPN
bionys-568	229	21	,	,	PUNCT
bionys-568	229	22	m.c	m.c	PROPN
bionys-568	229	23	.	.	PROPN
bionys-568	229	24	,	,	PUNCT
bionys-568	229	25	burchell	burchell	PROPN
bionys-568	229	26	,	,	PUNCT
bionys-568	229	27	a.	a.	PROPN
bionys-568	229	28	,	,	PUNCT
bionys-568	229	29	houston	houston	PROPN
bionys-568	229	30	,	,	PUNCT
bionys-568	229	31	p.m.	p.m.	NOUN
bionys-568	229	32	,	,	PUNCT
bionys-568	229	33	schmoll	schmoll	NOUN
bionys-568	229	34	,	,	PUNCT
bionys-568	229	35	d.	d.	PROPN
bionys-568	229	36	,	,	PUNCT
bionys-568	229	37	jamieson	jamieson	PROPN
bionys-568	229	38	,	,	PUNCT
bionys-568	229	39	p.	p.	PROPN
bionys-568	229	40	,	,	PUNCT
bionys-568	229	41	best	good	ADJ
bionys-568	229	42	,	,	PUNCT
bionys-568	229	43	r.	r.	PROPN
bionys-568	229	44	,	,	PUNCT
bionys-568	229	45	brown	brown	PROPN
bionys-568	229	46	,	,	PUNCT
bionys-568	229	47	r.	r.	PROPN
bionys-568	229	48	,	,	PUNCT
bionys-568	229	49	edwards	edwards	PROPN
bionys-568	229	50	,	,	PUNCT
bionys-568	229	51	c.r	c.r	PROPN
bionys-568	229	52	.	.	PROPN
bionys-568	229	53	,	,	PUNCT
bionys-568	229	54	seckl	seckl	NOUN
bionys-568	229	55	,	,	PUNCT
bionys-568	229	56	j.r	j.r	PROPN
bionys-568	229	57	.	.	PROPN
bionys-568	229	58	,	,	PUNCT
bionys-568	229	59	&	&	CCONJ
bionys-568	229	60	mullins	mullins	PROPN
bionys-568	229	61	,	,	PUNCT
bionys-568	229	62	j.j	j.j	PROPN
bionys-568	229	63	.	.	PROPN
bionys-568	229	64	(	(	PUNCT
bionys-568	229	65	1997	1997	NUM
bionys-568	229	66	)	)	PUNCT
bionys-568	229	67	.	.	PUNCT
bionys-568	230	1	11β	11β	PROPN
bionys-568	230	2	-	-	PUNCT
bionys-568	230	3	hydroxysteroid	hydroxysteroid	VERB
bionys-568	230	4	dehydrogenase	dehydrogenase	NOUN
bionys-568	230	5	type	type	NOUN
bionys-568	230	6	1	1	NUM
bionys-568	230	7	knockout	knockout	NOUN
bionys-568	230	8	mice	mouse	NOUN
bionys-568	230	9	show	show	NOUN
bionys-568	230	10	attenuated	attenuate	VERB
bionys-568	230	11	glucocorticoidinducible	glucocorticoidinducible	ADJ
bionys-568	230	12	responses	response	NOUN
bionys-568	230	13	and	and	CCONJ
bionys-568	230	14	resist	resist	VERB
bionys-568	230	15	hyperglycemia	hyperglycemia	NOUN
bionys-568	230	16	on	on	ADP
bionys-568	230	17	obesity	obesity	NOUN
bionys-568	230	18	or	or	CCONJ
bionys-568	230	19	stress	stress	NOUN
bionys-568	230	20	.	.	PUNCT
bionys-568	231	1	proceedings	proceeding	NOUN
bionys-568	231	2	of	of	ADP
bionys-568	231	3	the	the	DET
bionys-568	231	4	national	national	PROPN
bionys-568	231	5	academy	academy	PROPN
bionys-568	231	6	of	of	ADP
bionys-568	231	7	sciences	sciences	PROPN
bionys-568	231	8	usa	usa	PROPN
bionys-568	231	9	,	,	PUNCT
bionys-568	231	10	94(26	94(26	PROPN
bionys-568	231	11	)	)	PUNCT
bionys-568	231	12	,	,	PUNCT
bionys-568	231	13	14924	14924	NUM
bionys-568	231	14	-	-	SYM
bionys-568	231	15	14929	14929	NUM
bionys-568	231	16	.	.	PUNCT
bionys-568	232	1	biologica	biologica	PROPN
bionys-568	232	2	nyssana	nyssana	PROPN
bionys-568	233	1	●	●	PUNCT
bionys-568	233	2	16	16	NUM
bionys-568	233	3	(	(	PUNCT
bionys-568	233	4	1	1	NUM
bionys-568	233	5	)	)	PUNCT
bionys-568	233	6	june	june	PROPN
bionys-568	233	7	2025	2025	NUM
bionys-568	233	8	:	:	PUNCT
bionys-568	233	9	287	287	NUM
bionys-568	233	10	-	-	SYM
bionys-568	233	11	296	296	NUM
bionys-568	233	12	al	al	PROPN
bionys-568	233	13	-	-	PUNCT
bionys-568	233	14	khaykanee	khaykanee	PROPN
bionys-568	233	15	et	et	PROPN
bionys-568	233	16	al	al	PROPN
bionys-568	233	17	.	.	PUNCT
bionys-568	234	1	●	●	PUNCT
bionys-568	234	2	role	role	NOUN
bionys-568	234	3	of	of	ADP
bionys-568	234	4	11β	11β	PROPN
bionys-568	234	5	-	-	PUNCT
bionys-568	234	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	234	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	234	8	gene	gene	NOUN
bionys-568	234	9	polymorphisms	polymorphism	NOUN
bionys-568	234	10	rs846910	rs846910	NOUN
bionys-568	234	11	and	and	CCONJ
bionys-568	234	12	rs12086634	rs12086634	PROPN
bionys-568	234	13	in	in	ADP
bionys-568	234	14	the	the	DET
bionys-568	234	15	etiology	etiology	NOUN
bionys-568	234	16	of	of	ADP
bionys-568	234	17	hepatocellular	hepatocellular	ADJ
bionys-568	234	18	carcinoma	carcinoma	NOUN
bionys-568	234	19	295	295	NUM
bionys-568	234	20	biologica	biologica	PROPN
bionys-568	234	21	nyssana	nyssana	PROPN
bionys-568	235	1	●	●	PUNCT
bionys-568	235	2	16	16	NUM
bionys-568	235	3	(	(	PUNCT
bionys-568	235	4	1	1	NUM
bionys-568	235	5	)	)	PUNCT
bionys-568	235	6	june	june	PROPN
bionys-568	235	7	2025	2025	NUM
bionys-568	235	8	:	:	PUNCT
bionys-568	235	9	287	287	NUM
bionys-568	235	10	-	-	SYM
bionys-568	235	11	296	296	NUM
bionys-568	235	12	al	al	PROPN
bionys-568	235	13	-	-	PUNCT
bionys-568	235	14	khaykanee	khaykanee	PROPN
bionys-568	235	15	et	et	PROPN
bionys-568	235	16	al	al	PROPN
bionys-568	235	17	.	.	PUNCT
bionys-568	236	1	●	●	PUNCT
bionys-568	236	2	role	role	NOUN
bionys-568	236	3	of	of	ADP
bionys-568	236	4	11β	11β	PROPN
bionys-568	236	5	-	-	PUNCT
bionys-568	236	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	236	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	236	8	gene	gene	NOUN
bionys-568	236	9	polymorphisms	polymorphism	NOUN
bionys-568	236	10	rs846910	rs846910	NOUN
bionys-568	236	11	and	and	CCONJ
bionys-568	236	12	rs12086634	rs12086634	PROPN
bionys-568	236	13	in	in	ADP
bionys-568	236	14	the	the	DET
bionys-568	236	15	etiology	etiology	NOUN
bionys-568	236	16	of	of	ADP
bionys-568	236	17	hepatocellular	hepatocellular	ADJ
bionys-568	236	18	carcinoma	carcinoma	NOUN
bionys-568	236	19	doi	doi	NOUN
bionys-568	236	20	:	:	PUNCT
bionys-568	236	21	10.1073	10.1073	NUM
bionys-568	236	22	/	/	SYM
bionys-568	236	23	pnas.94.26.14924	pnas.94.26.14924	NOUN
bionys-568	236	24	.	.	PUNCT
bionys-568	236	25	,	,	PUNCT
bionys-568	236	26	leowattana	leowattana	PROPN
bionys-568	236	27	,	,	PUNCT
bionys-568	236	28	w.	w.	PROPN
bionys-568	236	29	,	,	PUNCT
bionys-568	236	30	leowattana	leowattana	PROPN
bionys-568	236	31	,	,	PUNCT
bionys-568	236	32	t.	t.	PROPN
bionys-568	236	33	,	,	PUNCT
bionys-568	236	34	&	&	CCONJ
bionys-568	236	35	leowattana‏	leowattana‏	PROPN
bionys-568	236	36	p.	p.	NOUN
bionys-568	236	37	(	(	PUNCT
bionys-568	236	38	2023	2023	NUM
bionys-568	236	39	)	)	PUNCT
bionys-568	236	40	.	.	PUNCT
bionys-568	237	1	systemic	systemic	ADJ
bionys-568	237	2	treatment	treatment	NOUN
bionys-568	237	3	for	for	ADP
bionys-568	237	4	unresectable	unresectable	ADJ
bionys-568	237	5	hepatocellular	hepatocellular	ADJ
bionys-568	237	6	carcinoma	carcinoma	NOUN
bionys-568	237	7	.	.	PUNCT
bionys-568	238	1	world	world	PROPN
bionys-568	238	2	journal	journal	PROPN
bionys-568	238	3	of	of	ADP
bionys-568	238	4	gastroenterology	gastroenterology	NOUN
bionys-568	238	5	,	,	PUNCT
bionys-568	238	6	29(10	29(10	NOUN
bionys-568	238	7	)	)	PUNCT
bionys-568	238	8	,	,	PUNCT
bionys-568	238	9	1551	1551	NUM
bionys-568	238	10	-	-	SYM
bionys-568	238	11	1568	1568	NUM
bionys-568	238	12	.	.	PUNCT
bionys-568	239	1	doi	doi	NOUN
bionys-568	239	2	:	:	PUNCT
bionys-568	239	3	10.3748/	10.3748/	NUM
bionys-568	239	4	wjg.v29.i10.1551	wjg.v29.i10.1551	PROPN
bionys-568	239	5	.	.	PUNCT
bionys-568	240	1	liu	liu	PROPN
bionys-568	240	2	,	,	PUNCT
bionys-568	240	3	x.	x.	PROPN
bionys-568	240	4	,	,	PUNCT
bionys-568	240	5	tan	tan	PROPN
bionys-568	240	6	,	,	PUNCT
bionys-568	240	7	x.l	x.l	PROPN
bionys-568	240	8	.	.	PROPN
bionys-568	240	9	,	,	PUNCT
bionys-568	240	10	xia	xia	PROPN
bionys-568	240	11	,	,	PUNCT
bionys-568	240	12	m.	m.	NOUN
bionys-568	240	13	,	,	PUNCT
bionys-568	240	14	wu	wu	PROPN
bionys-568	240	15	,	,	PUNCT
bionys-568	240	16	c.	c.	PROPN
bionys-568	240	17	,	,	PUNCT
bionys-568	240	18	song	song	NOUN
bionys-568	240	19	,	,	PUNCT
bionys-568	240	20	j.	j.	PROPN
bionys-568	240	21	,	,	PUNCT
bionys-568	240	22	wu	wu	PROPN
bionys-568	240	23	,	,	PUNCT
bionys-568	240	24	j.j	j.j	PROPN
bionys-568	240	25	.	.	PROPN
bionys-568	240	26	,	,	PUNCT
bionys-568	240	27	laurence	laurence	PROPN
bionys-568	240	28	,	,	PUNCT
bionys-568	240	29	a.	a.	PROPN
bionys-568	240	30	,	,	PUNCT
bionys-568	240	31	xie	xie	PROPN
bionys-568	240	32	,	,	PUNCT
bionys-568	240	33	q.g	q.g	PROPN
bionys-568	240	34	.	.	PROPN
bionys-568	240	35	,	,	PUNCT
bionys-568	240	36	zhang	zhang	PROPN
bionys-568	240	37	,	,	PUNCT
bionys-568	240	38	m.z	m.z	PROPN
bionys-568	240	39	.	.	PROPN
bionys-568	240	40	,	,	PUNCT
bionys-568	240	41	liang	liang	PROPN
bionys-568	240	42	,	,	PUNCT
bionys-568	240	43	h.f	h.f	PROPN
bionys-568	240	44	.	.	PROPN
bionys-568	240	45	,	,	PUNCT
bionys-568	240	46	zhang	zhang	PROPN
bionys-568	240	47	,	,	PUNCT
bionys-568	240	48	b.x	b.x	PROPN
bionys-568	240	49	.	.	PROPN
bionys-568	240	50	,	,	PUNCT
bionys-568	240	51	&	&	CCONJ
bionys-568	240	52	chen	chen	PROPN
bionys-568	240	53	,	,	PUNCT
bionys-568	240	54	x.p	x.p	PROPN
bionys-568	240	55	.	.	PUNCT
bionys-568	241	1	(	(	PUNCT
bionys-568	241	2	2015	2015	NUM
bionys-568	241	3	)	)	PUNCT
bionys-568	241	4	.	.	PUNCT
bionys-568	242	1	loss	loss	NOUN
bionys-568	242	2	of	of	ADP
bionys-568	242	3	11βhsd1	11βhsd1	NUM
bionys-568	242	4	enhances	enhance	NOUN
bionys-568	242	5	glycolysis	glycolysis	NOUN
bionys-568	242	6	,	,	PUNCT
bionys-568	242	7	facilitates	facilitate	VERB
bionys-568	242	8	intrahepatic	intrahepatic	ADJ
bionys-568	242	9	metastasis	metastasis	NOUN
bionys-568	242	10	,	,	PUNCT
bionys-568	242	11	and	and	CCONJ
bionys-568	242	12	indicates	indicate	VERB
bionys-568	242	13	poor	poor	ADJ
bionys-568	242	14	prognosis	prognosis	NOUN
bionys-568	242	15	in	in	ADP
bionys-568	242	16	hepatocellular	hepatocellular	ADJ
bionys-568	242	17	carcinoma	carcinoma	NOUN
bionys-568	242	18	.	.	PUNCT
bionys-568	243	1	oncotarget	oncotarget	NOUN
bionys-568	243	2	,	,	PUNCT
bionys-568	243	3	7(2	7(2	NUM
bionys-568	243	4	)	)	PUNCT
bionys-568	243	5	,	,	PUNCT
bionys-568	243	6	20382053	20382053	NUM
bionys-568	243	7	.	.	PUNCT
bionys-568	244	1	doi	doi	NOUN
bionys-568	244	2	:	:	PUNCT
bionys-568	244	3	10.18632	10.18632	NUM
bionys-568	244	4	/	/	SYM
bionys-568	244	5	oncotarget.6661	oncotarget.6661	PROPN
bionys-568	244	6	.	.	PROPN
bionys-568	244	7	‏	‏	PUNCT
bionys-568	244	8	lutz	lutz	PROPN
bionys-568	244	9	,	,	PUNCT
bionys-568	244	10	s.z	s.z	PROPN
bionys-568	244	11	.	.	PROPN
bionys-568	244	12	,	,	PUNCT
bionys-568	244	13	peter	peter	PROPN
bionys-568	244	14	,	,	PUNCT
bionys-568	244	15	a.	a.	PROPN
bionys-568	244	16	,	,	PUNCT
bionys-568	244	17	machicao	machicao	PROPN
bionys-568	244	18	,	,	PUNCT
bionys-568	244	19	f.	f.	PROPN
bionys-568	244	20	,	,	PUNCT
bionys-568	244	21	lamprinou	lamprinou	ADJ
bionys-568	244	22	,	,	PUNCT
bionys-568	244	23	a.	a.	NOUN
bionys-568	244	24	,	,	PUNCT
bionys-568	244	25	machann	machann	PROPN
bionys-568	244	26	,	,	PUNCT
bionys-568	244	27	j.	j.	PROPN
bionys-568	244	28	,	,	PUNCT
bionys-568	244	29	schick	schick	PROPN
bionys-568	244	30	,	,	PUNCT
bionys-568	244	31	f.	f.	PROPN
bionys-568	244	32	,	,	PUNCT
bionys-568	244	33	königsrainer	königsrainer	PROPN
bionys-568	244	34	,	,	PUNCT
bionys-568	244	35	i.	i.	NOUN
bionys-568	244	36	,	,	PUNCT
bionys-568	244	37	königsrainer	königsrainer	PROPN
bionys-568	244	38	,	,	PUNCT
bionys-568	244	39	a.	a.	NOUN
bionys-568	244	40	,	,	PUNCT
bionys-568	244	41	fritsche	fritsche	PROPN
bionys-568	244	42	,	,	PUNCT
bionys-568	244	43	a.	a.	NOUN
bionys-568	244	44	,	,	PUNCT
bionys-568	244	45	staiger	staiger	NOUN
bionys-568	244	46	,	,	PUNCT
bionys-568	244	47	h.	h.	PROPN
bionys-568	244	48	,	,	PUNCT
bionys-568	244	49	häring	häring	NOUN
bionys-568	244	50	,	,	PUNCT
bionys-568	244	51	h.u	h.u	PROPN
bionys-568	244	52	.	.	PROPN
bionys-568	244	53	,	,	PUNCT
bionys-568	244	54	stefan	stefan	PROPN
bionys-568	244	55	,	,	PUNCT
bionys-568	244	56	n.	n.	PROPN
bionys-568	244	57	,	,	PUNCT
bionys-568	244	58	&	&	CCONJ
bionys-568	244	59	kantartzis	kantartzis	PROPN
bionys-568	244	60	,	,	PUNCT
bionys-568	244	61	k.	k.	PROPN
bionys-568	244	62	(	(	PUNCT
bionys-568	244	63	2016	2016	NUM
bionys-568	244	64	)	)	PUNCT
bionys-568	244	65	.	.	PUNCT
bionys-568	245	1	genetic	genetic	ADJ
bionys-568	245	2	variation	variation	NOUN
bionys-568	245	3	in	in	ADP
bionys-568	245	4	the	the	DET
bionys-568	245	5	11β	11β	NUM
bionys-568	245	6	-	-	PUNCT
bionys-568	245	7	hydroxysteroid	hydroxysteroid	ADJ
bionys-568	245	8	-	-	PUNCT
bionys-568	245	9	dehydrogenase	dehydrogenase	NOUN
bionys-568	245	10	1	1	NUM
bionys-568	245	11	gene	gene	NOUN
bionys-568	245	12	determines	determine	VERB
bionys-568	245	13	nafld	nafld	ADJ
bionys-568	245	14	and	and	CCONJ
bionys-568	245	15	visceral	visceral	ADJ
bionys-568	245	16	obesity	obesity	NOUN
bionys-568	245	17	.	.	PUNCT
bionys-568	246	1	the	the	DET
bionys-568	246	2	journal	journal	NOUN
bionys-568	246	3	of	of	ADP
bionys-568	246	4	clinical	clinical	ADJ
bionys-568	246	5	endocrinology	endocrinology	NOUN
bionys-568	246	6	&	&	CCONJ
bionys-568	246	7	metabolism	metabolism	NOUN
bionys-568	246	8	,	,	PUNCT
bionys-568	246	9	101(12	101(12	NUM
bionys-568	246	10	)	)	PUNCT
bionys-568	246	11	,	,	PUNCT
bionys-568	246	12	4743	4743	NUM
bionys-568	246	13	-	-	SYM
bionys-568	246	14	4751	4751	NUM
bionys-568	246	15	.	.	PUNCT
bionys-568	247	1	doi	doi	NOUN
bionys-568	247	2	:	:	PUNCT
bionys-568	247	3	10.1210	10.1210	NUM
bionys-568	247	4	/	/	SYM
bionys-568	247	5	jc.2016	jc.2016	PROPN
bionys-568	247	6	-	-	PUNCT
bionys-568	247	7	2498	2498	NUM
bionys-568	247	8	.	.	PUNCT
bionys-568	248	1	mesri	mesri	PROPN
bionys-568	248	2	,	,	PUNCT
bionys-568	248	3	e.a	e.a	PROPN
bionys-568	248	4	.	.	PROPN
bionys-568	248	5	,	,	PUNCT
bionys-568	248	6	feitelson	feitelson	PROPN
bionys-568	248	7	,	,	PUNCT
bionys-568	248	8	m.a	m.a	PROPN
bionys-568	248	9	.	.	PROPN
bionys-568	248	10	,	,	PUNCT
bionys-568	248	11	&	&	CCONJ
bionys-568	248	12	munger	munger	PROPN
bionys-568	248	13	,	,	PUNCT
bionys-568	248	14	k.	k.	PROPN
bionys-568	248	15	(	(	PUNCT
bionys-568	248	16	2014	2014	NUM
bionys-568	248	17	)	)	PUNCT
bionys-568	248	18	.	.	PUNCT
bionys-568	249	1	human	human	ADJ
bionys-568	249	2	viral	viral	ADJ
bionys-568	249	3	oncogenesis	oncogenesis	NOUN
bionys-568	249	4	:	:	PUNCT
bionys-568	249	5	a	a	DET
bionys-568	249	6	cancer	cancer	NOUN
bionys-568	249	7	hallmarks	hallmark	VERB
bionys-568	249	8	analysis	analysis	NOUN
bionys-568	249	9	.	.	PUNCT
bionys-568	250	1	cell	cell	NOUN
bionys-568	250	2	host	host	NOUN
bionys-568	250	3	&	&	CCONJ
bionys-568	250	4	microbe	microbe	PROPN
bionys-568	250	5	,	,	PUNCT
bionys-568	250	6	15(3	15(3	NUM
bionys-568	250	7	)	)	PUNCT
bionys-568	250	8	,	,	PUNCT
bionys-568	250	9	266	266	NUM
bionys-568	250	10	-	-	SYM
bionys-568	250	11	282.‏	282.‏	NUM
bionys-568	250	12	doi	doi	NOUN
bionys-568	250	13	:	:	PUNCT
bionys-568	250	14	10.1016	10.1016	NUM
bionys-568	250	15	/	/	SYM
bionys-568	250	16	j.chom.2014.02.011	j.chom.2014.02.011	PROPN
bionys-568	250	17	.	.	PUNCT
bionys-568	250	18	michalaki	michalaki	NOUN
bionys-568	250	19	,	,	PUNCT
bionys-568	250	20	m.	m.	NOUN
bionys-568	250	21	,	,	PUNCT
bionys-568	250	22	kyriazopoulou	kyriazopoulou	PROPN
bionys-568	250	23	,	,	PUNCT
bionys-568	250	24	v.	v.	PROPN
bionys-568	250	25	,	,	PUNCT
bionys-568	250	26	antonacopoulou	antonacopoulou	PROPN
bionys-568	250	27	,	,	PUNCT
bionys-568	250	28	a.	a.	PROPN
bionys-568	250	29	,	,	PUNCT
bionys-568	250	30	koika	koika	PROPN
bionys-568	250	31	,	,	PUNCT
bionys-568	250	32	v.	v.	NOUN
bionys-568	250	33	,	,	PUNCT
bionys-568	250	34	nikolaou	nikolaou	NOUN
bionys-568	250	35	,	,	PUNCT
bionys-568	250	36	m.	m.	NOUN
bionys-568	250	37	,	,	PUNCT
bionys-568	250	38	tsoukas	tsoukas	PROPN
bionys-568	250	39	,	,	PUNCT
bionys-568	250	40	a.	a.	NOUN
bionys-568	250	41	,	,	PUNCT
bionys-568	250	42	kalfarentzos	kalfarentzos	PROPN
bionys-568	250	43	,	,	PUNCT
bionys-568	250	44	f.	f.	PROPN
bionys-568	250	45	,	,	PUNCT
bionys-568	250	46	vagenakis	vagenakis	PROPN
bionys-568	250	47	,	,	PUNCT
bionys-568	250	48	a.g	a.g	PROPN
bionys-568	250	49	.	.	PROPN
bionys-568	250	50	,	,	PUNCT
bionys-568	250	51	voukelatou	voukelatou	PROPN
bionys-568	250	52	,	,	PUNCT
bionys-568	250	53	g.	g.	PROPN
bionys-568	250	54	,	,	PUNCT
bionys-568	250	55	&	&	CCONJ
bionys-568	250	56	papavassiliou	papavassiliou	PROPN
bionys-568	250	57	,	,	PUNCT
bionys-568	250	58	a.g	a.g	PROPN
bionys-568	250	59	.	.	PROPN
bionys-568	250	60	(	(	PUNCT
bionys-568	250	61	2012	2012	NUM
bionys-568	250	62	)	)	PUNCT
bionys-568	250	63	.	.	PUNCT
bionys-568	251	1	the	the	DET
bionys-568	251	2	expression	expression	NOUN
bionys-568	251	3	of	of	ADP
bionys-568	251	4	omental	omental	ADJ
bionys-568	251	5	11β	11β	NOUN
bionys-568	251	6	-	-	PUNCT
bionys-568	251	7	hsd1	hsd1	PROPN
bionys-568	251	8	is	be	AUX
bionys-568	251	9	not	not	PART
bionys-568	251	10	increased	increase	VERB
bionys-568	251	11	in	in	ADP
bionys-568	251	12	severely	severely	ADV
bionys-568	251	13	obese	obese	ADJ
bionys-568	251	14	women	woman	NOUN
bionys-568	251	15	with	with	ADP
bionys-568	251	16	metabolic	metabolic	NOUN
bionys-568	251	17	syndrome	syndrome	NOUN
bionys-568	251	18	.	.	PUNCT
bionys-568	252	1	obesity	obesity	NOUN
bionys-568	252	2	facts	fact	NOUN
bionys-568	252	3	,	,	PUNCT
bionys-568	252	4	5(1	5(1	NUM
bionys-568	252	5	)	)	PUNCT
bionys-568	252	6	,	,	PUNCT
bionys-568	252	7	104–111	104–111	NUM
bionys-568	252	8	.	.	PUNCT
bionys-568	253	1	doi	doi	NOUN
bionys-568	253	2	:	:	PUNCT
bionys-568	253	3	10.1159/000336755	10.1159/000336755	NUM
bionys-568	253	4	.	.	PUNCT
bionys-568	254	1	moon	moon	PROPN
bionys-568	254	2	,	,	PUNCT
bionys-568	254	3	s.s	s.s	PROPN
bionys-568	254	4	.	.	PROPN
bionys-568	254	5	,	,	PUNCT
bionys-568	254	6	lee	lee	PROPN
bionys-568	254	7	,	,	PUNCT
bionys-568	254	8	y.s	y.s	PROPN
bionys-568	254	9	.	.	PROPN
bionys-568	254	10	,	,	PUNCT
bionys-568	254	11	kim	kim	PROPN
bionys-568	254	12	,	,	PUNCT
bionys-568	254	13	j.g	j.g	PROPN
bionys-568	254	14	.	.	PROPN
bionys-568	254	15	,	,	PUNCT
bionys-568	254	16	&	&	CCONJ
bionys-568	254	17	lee	lee	PROPN
bionys-568	254	18	,	,	PUNCT
bionys-568	254	19	i.k	i.k	PROPN
bionys-568	254	20	.	.	PROPN
bionys-568	254	21	(	(	PUNCT
bionys-568	254	22	2013	2013	NUM
bionys-568	254	23	)	)	PUNCT
bionys-568	254	24	.	.	PUNCT
bionys-568	255	1	association	association	PROPN
bionys-568	255	2	of	of	ADP
bionys-568	255	3	11β	11β	PROPN
bionys-568	255	4	-	-	PUNCT
bionys-568	255	5	hydroxysteroid	hydroxysteroid	VERB
bionys-568	255	6	dehydrogenase	dehydrogenase	NOUN
bionys-568	255	7	type	type	NOUN
bionys-568	255	8	1	1	NUM
bionys-568	255	9	gene	gene	NOUN
bionys-568	255	10	polymorphisms	polymorphism	NOUN
bionys-568	255	11	with	with	ADP
bionys-568	255	12	serum	serum	NOUN
bionys-568	255	13	alanine	alanine	NOUN
bionys-568	255	14	aminotransferase	aminotransferase	NOUN
bionys-568	255	15	activity	activity	NOUN
bionys-568	255	16	.	.	PUNCT
bionys-568	256	1	diabetes	diabetes	NOUN
bionys-568	256	2	research	research	NOUN
bionys-568	256	3	and	and	CCONJ
bionys-568	256	4	clinical	clinical	ADJ
bionys-568	256	5	practice	practice	NOUN
bionys-568	256	6	,	,	PUNCT
bionys-568	256	7	99(3	99(3	NUM
bionys-568	256	8	)	)	PUNCT
bionys-568	256	9	,	,	PUNCT
bionys-568	256	10	343	343	NUM
bionys-568	256	11	-	-	SYM
bionys-568	256	12	350	350	NUM
bionys-568	256	13	.	.	PUNCT
bionys-568	257	1	doi	doi	NOUN
bionys-568	257	2	:	:	PUNCT
bionys-568	257	3	10.1016	10.1016	NUM
bionys-568	257	4	/	/	SYM
bionys-568	257	5	j.diabres.2012.12.020	j.diabres.2012.12.020	X
bionys-568	257	6	morgan	morgan	PROPN
bionys-568	257	7	,	,	PUNCT
bionys-568	257	8	s.a	s.a	PROPN
bionys-568	257	9	.	.	PROPN
bionys-568	257	10	&	&	CCONJ
bionys-568	257	11	tomlinson	tomlinson	PROPN
bionys-568	257	12	,	,	PUNCT
bionys-568	257	13	j.w	j.w	PROPN
bionys-568	257	14	.	.	PROPN
bionys-568	258	1	(	(	PUNCT
bionys-568	258	2	2010	2010	NUM
bionys-568	258	3	)	)	PUNCT
bionys-568	258	4	.	.	PUNCT
bionys-568	259	1	11β	11β	PROPN
bionys-568	259	2	-	-	PUNCT
bionys-568	259	3	hydroxysteroid	hydroxysteroid	VERB
bionys-568	259	4	dehydrogenase	dehydrogenase	NOUN
bionys-568	259	5	type	type	NOUN
bionys-568	259	6	1	1	NUM
bionys-568	259	7	inhibitors	inhibitor	NOUN
bionys-568	259	8	for	for	ADP
bionys-568	259	9	the	the	DET
bionys-568	259	10	treatment	treatment	NOUN
bionys-568	259	11	of	of	ADP
bionys-568	259	12	type	type	NOUN
bionys-568	259	13	2	2	NUM
bionys-568	259	14	diabetes	diabetes	NOUN
bionys-568	259	15	.	.	PUNCT
bionys-568	260	1	expert	expert	ADJ
bionys-568	260	2	opinion	opinion	NOUN
bionys-568	260	3	on	on	ADP
bionys-568	260	4	investigational	investigational	ADJ
bionys-568	260	5	drugs	drug	NOUN
bionys-568	260	6	,	,	PUNCT
bionys-568	260	7	19(9	19(9	NUM
bionys-568	260	8	)	)	PUNCT
bionys-568	260	9	,	,	PUNCT
bionys-568	260	10	1067	1067	NUM
bionys-568	260	11	-	-	SYM
bionys-568	260	12	1076	1076	NUM
bionys-568	260	13	.	.	PUNCT
bionys-568	261	1	doi.org	doi.org	NUM
bionys-568	261	2	/10.1517/13543784.2010.504713	/10.1517/13543784.2010.504713	PUNCT
bionys-568	261	3	.	.	PUNCT
bionys-568	262	1	nair	nair	PROPN
bionys-568	262	2	,	,	PUNCT
bionys-568	262	3	s.	s.	PROPN
bionys-568	262	4	,	,	PUNCT
bionys-568	262	5	lee	lee	PROPN
bionys-568	262	6	,	,	PUNCT
bionys-568	262	7	y.	y.	PROPN
bionys-568	262	8	,	,	PUNCT
bionys-568	262	9	lindsay	lindsay	PROPN
bionys-568	262	10	,	,	PUNCT
bionys-568	262	11	r.	r.	PROPN
bionys-568	262	12	,	,	PUNCT
bionys-568	262	13	walker	walker	PROPN
bionys-568	262	14	,	,	PUNCT
bionys-568	262	15	b.r	b.r	PROPN
bionys-568	262	16	.	.	PROPN
bionys-568	262	17	,	,	PUNCT
bionys-568	262	18	tataranni	tataranni	PROPN
bionys-568	262	19	,	,	PUNCT
bionys-568	262	20	p.a	p.a	PROPN
bionys-568	262	21	.	.	PROPN
bionys-568	262	22	,	,	PUNCT
bionys-568	262	23	bogardus	bogardus	PROPN
bionys-568	262	24	,	,	PUNCT
bionys-568	262	25	c.	c.	PROPN
bionys-568	262	26	,	,	PUNCT
bionys-568	262	27	baier	baier	NOUN
bionys-568	262	28	,	,	PUNCT
bionys-568	262	29	l.j	l.j	PROPN
bionys-568	262	30	.	.	PROPN
bionys-568	262	31	,	,	PUNCT
bionys-568	262	32	&	&	CCONJ
bionys-568	262	33	permana	permana	PROPN
bionys-568	262	34	,	,	PUNCT
bionys-568	262	35	p.a	p.a	PROPN
bionys-568	262	36	.	.	PROPN
bionys-568	262	37	(	(	PUNCT
bionys-568	262	38	2004	2004	NUM
bionys-568	262	39	)	)	PUNCT
bionys-568	262	40	.	.	PUNCT
bionys-568	263	1	11β	11β	PROPN
bionys-568	263	2	-	-	PUNCT
bionys-568	263	3	hydroxysteroid	hydroxysteroid	VERB
bionys-568	263	4	dehydrogenase	dehydrogenase	NOUN
bionys-568	263	5	type	type	NOUN
bionys-568	263	6	1	1	NUM
bionys-568	263	7	:	:	PUNCT
bionys-568	263	8	genetic	genetic	ADJ
bionys-568	263	9	polymorphisms	polymorphism	NOUN
bionys-568	263	10	are	be	AUX
bionys-568	263	11	associated	associate	VERB
bionys-568	263	12	with	with	ADP
bionys-568	263	13	type	type	NOUN
bionys-568	263	14	2	2	NUM
bionys-568	263	15	diabetes	diabetes	NOUN
bionys-568	263	16	in	in	ADP
bionys-568	263	17	pima	pima	PROPN
bionys-568	263	18	indians	indians	PROPN
bionys-568	263	19	independently	independently	ADV
bionys-568	263	20	of	of	ADP
bionys-568	263	21	obesity	obesity	NOUN
bionys-568	263	22	and	and	CCONJ
bionys-568	263	23	expression	expression	NOUN
bionys-568	263	24	in	in	ADP
bionys-568	263	25	adipocyte	adipocyte	NOUN
bionys-568	263	26	and	and	CCONJ
bionys-568	263	27	muscle	muscle	NOUN
bionys-568	263	28	.	.	PUNCT
bionys-568	264	1	diabetologia	diabetologia	NOUN
bionys-568	264	2	,	,	PUNCT
bionys-568	264	3	47(6	47(6	NUM
bionys-568	264	4	):	):	PUNCT
bionys-568	264	5	10881095	10881095	NUM
bionys-568	264	6	.	.	PUNCT
bionys-568	265	1	doi	doi	NOUN
bionys-568	265	2	:	:	PUNCT
bionys-568	265	3	10.1007	10.1007	NUM
bionys-568	265	4	/	/	SYM
bionys-568	265	5	s00125	s00125	NOUN
bionys-568	265	6	-	-	PUNCT
bionys-568	265	7	004	004	NUM
bionys-568	265	8	-	-	PUNCT
bionys-568	265	9	1407	1407	NUM
bionys-568	265	10	-	-	SYM
bionys-568	265	11	6	6	NUM
bionys-568	265	12	.	.	PUNCT
bionys-568	266	1	razavi	razavi	PROPN
bionys-568	266	2	-	-	PUNCT
bionys-568	266	3	shearer	shearer	PROPN
bionys-568	266	4	,	,	PUNCT
bionys-568	266	5	d.	d.	PROPN
bionys-568	266	6	,	,	PUNCT
bionys-568	266	7	gamkrelidze	gamkrelidze	PROPN
bionys-568	266	8	,	,	PUNCT
bionys-568	266	9	i.	i.	PROPN
bionys-568	266	10	,	,	PUNCT
bionys-568	266	11	nguyen	nguyen	PROPN
bionys-568	266	12	,	,	PUNCT
bionys-568	266	13	m.h	m.h	PROPN
bionys-568	266	14	.	.	PROPN
bionys-568	266	15	,	,	PUNCT
bionys-568	266	16	chen	chen	PROPN
bionys-568	266	17	,	,	PUNCT
bionys-568	266	18	d.s	d.s	PROPN
bionys-568	266	19	.	.	PROPN
bionys-568	266	20	,	,	PUNCT
bionys-568	266	21	van	van	PROPN
bionys-568	266	22	damme	damme	PROPN
bionys-568	266	23	,	,	PUNCT
bionys-568	266	24	p.	p.	NOUN
bionys-568	266	25	,	,	PUNCT
bionys-568	266	26	abbas	abbas	PROPN
bionys-568	266	27	,	,	PUNCT
bionys-568	266	28	z.	z.	PROPN
bionys-568	266	29	,	,	PUNCT
bionys-568	266	30	...	...	PUNCT
bionys-568	266	31	&	&	CCONJ
bionys-568	266	32	roberts	roberts	PROPN
bionys-568	266	33	,	,	PUNCT
bionys-568	266	34	s.k	s.k	PROPN
bionys-568	266	35	.	.	PROPN
bionys-568	266	36	(	(	PUNCT
bionys-568	266	37	2018	2018	NUM
bionys-568	266	38	)	)	PUNCT
bionys-568	266	39	.	.	PUNCT
bionys-568	267	1	global	global	ADJ
bionys-568	267	2	prevalence	prevalence	NOUN
bionys-568	267	3	,	,	PUNCT
bionys-568	267	4	treatment	treatment	NOUN
bionys-568	267	5	,	,	PUNCT
bionys-568	267	6	and	and	CCONJ
bionys-568	267	7	prevention	prevention	NOUN
bionys-568	267	8	of	of	ADP
bionys-568	267	9	hepatitis	hepatitis	PROPN
bionys-568	267	10	b	b	PROPN
bionys-568	267	11	virus	virus	NOUN
bionys-568	267	12	infection	infection	NOUN
bionys-568	267	13	in	in	ADP
bionys-568	267	14	2016	2016	NUM
bionys-568	267	15	:	:	PUNCT
bionys-568	267	16	a	a	DET
bionys-568	267	17	modelling	model	VERB
bionys-568	267	18	study	study	NOUN
bionys-568	267	19	.	.	PUNCT
bionys-568	268	1	the	the	DET
bionys-568	268	2	lancet	lancet	PROPN
bionys-568	268	3	gastroenterology	gastroenterology	NOUN
bionys-568	268	4	&	&	CCONJ
bionys-568	268	5	hepatology	hepatology	NOUN
bionys-568	268	6	,	,	PUNCT
bionys-568	268	7	3(6	3(6	NUM
bionys-568	268	8	)	)	PUNCT
bionys-568	268	9	,	,	PUNCT
bionys-568	268	10	383	383	NUM
bionys-568	268	11	-	-	SYM
bionys-568	268	12	403.‏	403.‏	NUM
bionys-568	268	13	doi	doi	NOUN
bionys-568	268	14	:	:	PUNCT
bionys-568	268	15	10.1016	10.1016	NUM
bionys-568	268	16	/	/	SYM
bionys-568	268	17	s24681253(18)30056	s24681253(18)30056	PROPN
bionys-568	268	18	-	-	PUNCT
bionys-568	268	19	6	6	NUM
bionys-568	268	20	.	.	PUNCT
bionys-568	269	1	rizzo	rizzo	PROPN
bionys-568	269	2	,	,	PUNCT
bionys-568	269	3	g.e.m	g.e.m	NOUN
bionys-568	269	4	.	.	PROPN
bionys-568	269	5	,	,	PUNCT
bionys-568	269	6	cabibbo	cabibbo	PROPN
bionys-568	269	7	,	,	PUNCT
bionys-568	269	8	g.	g.	PROPN
bionys-568	269	9	,	,	PUNCT
bionys-568	269	10	&	&	CCONJ
bionys-568	269	11	craxì	craxì	PROPN
bionys-568	269	12	,	,	PUNCT
bionys-568	269	13	a.	a.	NOUN
bionys-568	269	14	(	(	PUNCT
bionys-568	269	15	2022	2022	NUM
bionys-568	269	16	)	)	PUNCT
bionys-568	269	17	.	.	PUNCT
bionys-568	270	1	hepatitis	hepatitis	PROPN
bionys-568	270	2	b	b	PROPN
bionys-568	270	3	virus	virus	NOUN
bionys-568	270	4	-	-	PUNCT
bionys-568	270	5	associated	associate	VERB
bionys-568	270	6	hepatocellular	hepatocellular	ADJ
bionys-568	270	7	carcinoma	carcinoma	NOUN
bionys-568	270	8	.	.	PUNCT
bionys-568	271	1	viruses	virus	NOUN
bionys-568	271	2	,	,	PUNCT
bionys-568	271	3	14(5	14(5	NUM
bionys-568	271	4	)	)	PUNCT
bionys-568	271	5	,	,	PUNCT
bionys-568	271	6	986.‏	986.‏	NUM
bionys-568	271	7	doi	doi	NOUN
bionys-568	271	8	:	:	PUNCT
bionys-568	271	9	10.3390/	10.3390/	NUM
bionys-568	271	10	v14050986	v14050986	PROPN
bionys-568	271	11	.	.	PUNCT
bionys-568	272	1	rumgay	rumgay	PROPN
bionys-568	272	2	,	,	PUNCT
bionys-568	272	3	h.	h.	PROPN
bionys-568	272	4	,	,	PUNCT
bionys-568	272	5	ferlay	ferlay	PROPN
bionys-568	272	6	,	,	PUNCT
bionys-568	272	7	j.	j.	PROPN
bionys-568	272	8	,	,	PUNCT
bionys-568	272	9	de	de	PROPN
bionys-568	272	10	martel	martel	PROPN
bionys-568	272	11	,	,	PUNCT
bionys-568	272	12	c.	c.	PROPN
bionys-568	272	13	,	,	PUNCT
bionys-568	272	14	georges	georges	PROPN
bionys-568	272	15	,	,	PUNCT
bionys-568	272	16	d.	d.	PROPN
bionys-568	272	17	,	,	PUNCT
bionys-568	272	18	ibrahim	ibrahim	PROPN
bionys-568	272	19	,	,	PUNCT
bionys-568	272	20	a.s	a.s	PROPN
bionys-568	272	21	.	.	PROPN
bionys-568	272	22	,	,	PUNCT
bionys-568	272	23	zheng	zheng	PROPN
bionys-568	272	24	,	,	PUNCT
bionys-568	272	25	r.	r.	PROPN
bionys-568	272	26	,	,	PUNCT
bionys-568	272	27	wei	wei	PROPN
bionys-568	272	28	,	,	PUNCT
bionys-568	272	29	w.	w.	PROPN
bionys-568	272	30	,	,	PUNCT
bionys-568	272	31	lemmens	lemmens	PROPN
bionys-568	272	32	,	,	PUNCT
bionys-568	272	33	v.e.p.p	v.e.p.p	PROPN
bionys-568	272	34	.	.	PROPN
bionys-568	272	35	,	,	PUNCT
bionys-568	272	36	&	&	CCONJ
bionys-568	272	37	soerjomataram	soerjomataram	PROPN
bionys-568	272	38	,	,	PUNCT
bionys-568	272	39	i.	i.	PROPN
bionys-568	272	40	(	(	PUNCT
bionys-568	272	41	2022	2022	NUM
bionys-568	272	42	)	)	PUNCT
bionys-568	272	43	global	global	ADJ
bionys-568	272	44	,	,	PUNCT
bionys-568	272	45	regional	regional	ADJ
bionys-568	272	46	and	and	CCONJ
bionys-568	272	47	national	national	ADJ
bionys-568	272	48	burden	burden	NOUN
bionys-568	272	49	of	of	ADP
bionys-568	272	50	primary	primary	ADJ
bionys-568	272	51	liver	liver	NOUN
bionys-568	272	52	cancer	cancer	NOUN
bionys-568	272	53	by	by	ADP
bionys-568	272	54	subtype	subtype	NOUN
bionys-568	272	55	.	.	PUNCT
bionys-568	273	1	european	european	ADJ
bionys-568	273	2	journal	journal	PROPN
bionys-568	273	3	of	of	ADP
bionys-568	273	4	cancer	cancer	NOUN
bionys-568	273	5	,	,	PUNCT
bionys-568	273	6	161	161	NUM
bionys-568	273	7	,	,	PUNCT
bionys-568	273	8	108118	108118	NUM
bionys-568	273	9	.	.	PUNCT
bionys-568	274	1	doi	doi	NOUN
bionys-568	274	2	:	:	PUNCT
bionys-568	274	3	10.1016	10.1016	NUM
bionys-568	274	4	/	/	SYM
bionys-568	274	5	j.ejca.2021.11.023	j.ejca.2021.11.023	PROPN
bionys-568	274	6	.	.	PROPN
bionys-568	274	7	seckl	seckl	PROPN
bionys-568	274	8	,	,	PUNCT
bionys-568	274	9	j.r	j.r	PROPN
bionys-568	274	10	.	.	PROPN
bionys-568	274	11	,	,	PUNCT
bionys-568	274	12	morton	morton	PROPN
bionys-568	274	13	,	,	PUNCT
bionys-568	274	14	n.m	n.m	PROPN
bionys-568	274	15	.	.	PROPN
bionys-568	274	16	,	,	PUNCT
bionys-568	274	17	chapman	chapman	PROPN
bionys-568	274	18	,	,	PUNCT
bionys-568	274	19	k.e	k.e	PROPN
bionys-568	274	20	.	.	PROPN
bionys-568	274	21	,	,	PUNCT
bionys-568	274	22	&	&	CCONJ
bionys-568	274	23	walker	walker	PROPN
bionys-568	274	24	,	,	PUNCT
bionys-568	274	25	b.r	b.r	PROPN
bionys-568	274	26	.	.	PROPN
bionys-568	274	27	(	(	PUNCT
bionys-568	274	28	2004	2004	NUM
bionys-568	274	29	)	)	PUNCT
bionys-568	274	30	.	.	PUNCT
bionys-568	275	1	glucocorticoids	glucocorticoid	NOUN
bionys-568	275	2	and	and	CCONJ
bionys-568	275	3	11betahydroxysteroid	11betahydroxysteroid	NUM
bionys-568	275	4	dehydrogenase	dehydrogenase	NOUN
bionys-568	275	5	in	in	ADP
bionys-568	275	6	adipose	adipose	ADJ
bionys-568	275	7	tissue	tissue	NOUN
bionys-568	275	8	.	.	PUNCT
bionys-568	276	1	recent	recent	ADJ
bionys-568	276	2	progress	progress	NOUN
bionys-568	276	3	in	in	ADP
bionys-568	276	4	hormone	hormone	NOUN
bionys-568	276	5	research	research	NOUN
bionys-568	276	6	,	,	PUNCT
bionys-568	276	7	59	59	NUM
bionys-568	276	8	,	,	PUNCT
bionys-568	276	9	359393	359393	NUM
bionys-568	276	10	.	.	PUNCT
bionys-568	277	1	doi	doi	NOUN
bionys-568	277	2	:	:	PUNCT
bionys-568	277	3	10.1210	10.1210	NUM
bionys-568	277	4	/	/	SYM
bionys-568	277	5	rp.59.1.359	rp.59.1.359	PROPN
bionys-568	277	6	shareef	shareef	PROPN
bionys-568	277	7	,	,	PUNCT
bionys-568	277	8	a.a	a.a	PROPN
bionys-568	277	9	.	.	PROPN
bionys-568	277	10	&	&	CCONJ
bionys-568	277	11	al	al	PROPN
bionys-568	277	12	-	-	PUNCT
bionys-568	277	13	attar	attar	PROPN
bionys-568	277	14	,	,	PUNCT
bionys-568	277	15	m.s	m.s	PROPN
bionys-568	277	16	.	.	PROPN
bionys-568	277	17	(	(	PUNCT
bionys-568	277	18	2019	2019	NUM
bionys-568	277	19	)	)	PUNCT
bionys-568	277	20	.	.	PUNCT
bionys-568	278	1	association	association	NOUN
bionys-568	278	2	study	study	NOUN
bionys-568	278	3	of	of	ADP
bionys-568	278	4	hsd11b1	hsd11b1	PROPN
bionys-568	278	5	rs12086634	rs12086634	PROPN
bionys-568	278	6	(	(	PUNCT
bionys-568	278	7	t	t	PROPN
bionys-568	278	8	>	>	NOUN
bionys-568	278	9	g	g	NOUN
bionys-568	278	10	)	)	PUNCT
bionys-568	278	11	gene	gene	NOUN
bionys-568	278	12	polymorphism	polymorphism	NOUN
bionys-568	278	13	with	with	ADP
bionys-568	278	14	polycystic	polycystic	ADJ
bionys-568	278	15	ovarian	ovarian	ADJ
bionys-568	278	16	syndrome	syndrome	NOUN
bionys-568	278	17	in	in	ADP
bionys-568	278	18	erbil	erbil	PROPN
bionys-568	278	19	province	province	PROPN
bionys-568	278	20	.	.	PUNCT
bionys-568	279	1	zanco	zanco	PROPN
bionys-568	279	2	journal	journal	PROPN
bionys-568	279	3	of	of	ADP
bionys-568	279	4	pure	pure	ADJ
bionys-568	279	5	and	and	CCONJ
bionys-568	279	6	applied	applied	ADJ
bionys-568	279	7	sciences	science	NOUN
bionys-568	279	8	,	,	PUNCT
bionys-568	279	9	31(5	31(5	NUM
bionys-568	279	10	)	)	PUNCT
bionys-568	279	11	,	,	PUNCT
bionys-568	279	12	36	36	NUM
bionys-568	279	13	-	-	SYM
bionys-568	279	14	43	43	NUM
bionys-568	279	15	.	.	PUNCT
bionys-568	280	1	doi:10.21271	doi:10.21271	NOUN
bionys-568	280	2	/	/	SYM
bionys-568	280	3	zipas	zipas	PROPN
bionys-568	280	4	.	.	PUNCT
bionys-568	281	1	soliman	soliman	PROPN
bionys-568	281	2	,	,	PUNCT
bionys-568	281	3	s.e	s.e	PROPN
bionys-568	281	4	.	.	PROPN
bionys-568	281	5	,	,	PUNCT
bionys-568	281	6	abd	abd	PROPN
bionys-568	281	7	el	el	PROPN
bionys-568	281	8	gayed	gaye	VERB
bionys-568	281	9	,	,	PUNCT
bionys-568	281	10	e	e	NOUN
bionys-568	281	11	m.	m.	NOUN
bionys-568	281	12	,	,	PUNCT
bionys-568	281	13	&	&	CCONJ
bionys-568	281	14	abd	abd	PROPN
bionys-568	281	15	el	el	PROPN
bionys-568	281	16	gayed	gaye	VERB
bionys-568	281	17	,	,	PUNCT
bionys-568	281	18	a	a	DET
bionys-568	281	19	m.	m.	NOUN
bionys-568	281	20	(	(	PUNCT
bionys-568	281	21	2020	2020	NUM
bionys-568	281	22	)	)	PUNCT
bionys-568	281	23	.	.	PUNCT
bionys-568	282	1	association	association	NOUN
bionys-568	282	2	of	of	ADP
bionys-568	282	3	the	the	DET
bionys-568	282	4	hsd11b1rs12086634	hsd11b1rs12086634	PROPN
bionys-568	282	5	(	(	PUNCT
bionys-568	282	6	t	t	PROPN
bionys-568	282	7	/	/	SYM
bionys-568	282	8	g	g	NOUN
bionys-568	282	9	)	)	PUNCT
bionys-568	282	10	gene	gene	NOUN
bionys-568	282	11	polymorphism	polymorphism	NOUN
bionys-568	282	12	and	and	CCONJ
bionys-568	282	13	il6	il6	NOUN
bionys-568	282	14	serum	serum	NOUN
bionys-568	282	15	level	level	NOUN
bionys-568	282	16	with	with	ADP
bionys-568	282	17	the	the	DET
bionys-568	282	18	risk	risk	NOUN
bionys-568	282	19	of	of	ADP
bionys-568	282	20	polycystic	polycystic	ADJ
bionys-568	282	21	ovary	ovary	ADJ
bionys-568	282	22	syndrome	syndrome	NOUN
bionys-568	282	23	.	.	PUNCT
bionys-568	283	1	meta	meta	PROPN
bionys-568	283	2	gene	gene	NOUN
bionys-568	283	3	,	,	PUNCT
bionys-568	283	4	23	23	NUM
bionys-568	283	5	,	,	PUNCT
bionys-568	283	6	100638	100638	NUM
bionys-568	283	7	.	.	PUNCT
bionys-568	284	1	doi	doi	NOUN
bionys-568	284	2	:	:	PUNCT
bionys-568	284	3	10.1016	10.1016	NUM
bionys-568	284	4	/	/	SYM
bionys-568	284	5	j.	j.	PROPN
bionys-568	284	6	mgene.2019.100638	mgene.2019.100638	PROPN
bionys-568	284	7	studzińska	studzińska	NOUN
bionys-568	284	8	,	,	PUNCT
bionys-568	284	9	r.	r.	PROPN
bionys-568	284	10	,	,	PUNCT
bionys-568	284	11	kupczyk	kupczyk	PROPN
bionys-568	284	12	,	,	PUNCT
bionys-568	284	13	d.	d.	PROPN
bionys-568	284	14	,	,	PUNCT
bionys-568	284	15	płazińska	płazińska	PROPN
bionys-568	284	16	,	,	PUNCT
bionys-568	284	17	a.	a.	NOUN
bionys-568	284	18	,	,	PUNCT
bionys-568	284	19	kołodziejska	kołodziejska	PROPN
bionys-568	284	20	,	,	PUNCT
bionys-568	284	21	r.	r.	PROPN
bionys-568	284	22	,	,	PUNCT
bionys-568	284	23	kosmalski	kosmalski	NOUN
bionys-568	284	24	,	,	PUNCT
bionys-568	284	25	t.	t.	PROPN
bionys-568	284	26	,	,	PUNCT
bionys-568	284	27	&	&	CCONJ
bionys-568	284	28	modzelewskabanachiewicz	modzelewskabanachiewicz	PROPN
bionys-568	284	29	,	,	PUNCT
bionys-568	284	30	b.	b.	PROPN
bionys-568	284	31	(	(	PUNCT
bionys-568	284	32	2018	2018	NUM
bionys-568	284	33	)	)	PUNCT
bionys-568	284	34	.	.	PUNCT
bionys-568	285	1	thiazolo	thiazolo	ADJ
bionys-568	286	1	[	[	X
bionys-568	286	2	3	3	NUM
bionys-568	286	3	,	,	PUNCT
bionys-568	286	4	2	2	NUM
bionys-568	286	5	-	-	SYM
bionys-568	286	6	a	a	PRON
bionys-568	286	7	]	]	X
bionys-568	286	8	pyrimidin-5	pyrimidin-5	NUM
bionys-568	286	9	-	-	PUNCT
bionys-568	286	10	one	one	NUM
bionys-568	286	11	derivatives	derivative	NOUN
bionys-568	286	12	as	as	ADP
bionys-568	286	13	a	a	DET
bionys-568	286	14	novel	novel	ADJ
bionys-568	286	15	class	class	NOUN
bionys-568	286	16	of	of	ADP
bionys-568	286	17	11β	11β	PROPN
bionys-568	286	18	-	-	PUNCT
bionys-568	286	19	hydroxysteroid	hydroxysteroid	VERB
bionys-568	286	20	dehydrogenase	dehydrogenase	NOUN
bionys-568	286	21	inhibitors	inhibitor	NOUN
bionys-568	286	22	.	.	PUNCT
bionys-568	287	1	bioorganic	bioorganic	ADJ
bionys-568	287	2	chemistry	chemistry	NOUN
bionys-568	287	3	,	,	PUNCT
bionys-568	287	4	81	81	NUM
bionys-568	287	5	,	,	PUNCT
bionys-568	287	6	21	21	NUM
bionys-568	287	7	-	-	SYM
bionys-568	287	8	26	26	NUM
bionys-568	287	9	.	.	PUNCT
bionys-568	288	1	doi	doi	NOUN
bionys-568	288	2	:	:	PUNCT
bionys-568	288	3	10.1016	10.1016	NUM
bionys-568	288	4	/	/	SYM
bionys-568	288	5	j.	j.	PROPN
bionys-568	288	6	bioorg.2018.07.033	bioorg.2018.07.033	PROPN
bionys-568	288	7	.	.	PUNCT
bionys-568	289	1	sung	sung	PROPN
bionys-568	289	2	,	,	PUNCT
bionys-568	289	3	h.	h.	PROPN
bionys-568	289	4	,	,	PUNCT
bionys-568	289	5	ferlay	ferlay	PROPN
bionys-568	289	6	,	,	PUNCT
bionys-568	289	7	j.	j.	PROPN
bionys-568	289	8	,	,	PUNCT
bionys-568	289	9	siegel	siegel	PROPN
bionys-568	289	10	,	,	PUNCT
bionys-568	289	11	r.l	r.l	PROPN
bionys-568	289	12	.	.	PROPN
bionys-568	289	13	,	,	PUNCT
bionys-568	289	14	laversanne	laversanne	PROPN
bionys-568	289	15	,	,	PUNCT
bionys-568	289	16	m.	m.	NOUN
bionys-568	289	17	,	,	PUNCT
bionys-568	289	18	soerjomataram	soerjomataram	PROPN
bionys-568	289	19	,	,	PUNCT
bionys-568	289	20	i.	i.	NOUN
bionys-568	289	21	,	,	PUNCT
bionys-568	289	22	jemal	jemal	PROPN
bionys-568	289	23	,	,	PUNCT
bionys-568	289	24	a.	a.	NOUN
bionys-568	289	25	,	,	PUNCT
bionys-568	289	26	&	&	CCONJ
bionys-568	289	27	bray	bray	PROPN
bionys-568	289	28	,	,	PUNCT
bionys-568	289	29	f.	f.	PROPN
bionys-568	289	30	(	(	PUNCT
bionys-568	289	31	2021	2021	NUM
bionys-568	289	32	)	)	PUNCT
bionys-568	289	33	.	.	PUNCT
bionys-568	290	1	global	global	ADJ
bionys-568	290	2	cancer	cancer	NOUN
bionys-568	290	3	statistics	statistic	NOUN
bionys-568	290	4	2020	2020	NUM
bionys-568	290	5	:	:	PUNCT
bionys-568	290	6	globocan	globocan	PROPN
bionys-568	290	7	estimates	estimate	NOUN
bionys-568	290	8	of	of	ADP
bionys-568	290	9	incidence	incidence	NOUN
bionys-568	290	10	and	and	CCONJ
bionys-568	290	11	mortality	mortality	NOUN
bionys-568	290	12	worldwide	worldwide	ADV
bionys-568	290	13	for	for	ADP
bionys-568	290	14	36	36	NUM
bionys-568	290	15	cancers	cancer	NOUN
bionys-568	290	16	in	in	ADP
bionys-568	290	17	185	185	NUM
bionys-568	290	18	countries	country	NOUN
bionys-568	290	19	.	.	PUNCT
bionys-568	291	1	ca	can	AUX
bionys-568	291	2	:	:	PUNCT
bionys-568	291	3	a	a	DET
bionys-568	291	4	cancer	cancer	NOUN
bionys-568	291	5	journal	journal	NOUN
bionys-568	291	6	for	for	ADP
bionys-568	291	7	clinicians	clinician	NOUN
bionys-568	291	8	,	,	PUNCT
bionys-568	291	9	71(3	71(3	NUM
bionys-568	291	10	)	)	PUNCT
bionys-568	291	11	,	,	PUNCT
bionys-568	291	12	209	209	NUM
bionys-568	291	13	-	-	SYM
bionys-568	291	14	249.‏	249.‏	NUM
bionys-568	291	15	doi	doi	NOUN
bionys-568	291	16	:	:	PUNCT
bionys-568	291	17	10.3322/	10.3322/	NUM
bionys-568	291	18	caac.21660	caac.21660	PROPN
bionys-568	291	19	.	.	NOUN
bionys-568	291	20	trépo	trépo	PROPN
bionys-568	291	21	,	,	PUNCT
bionys-568	291	22	c.	c.	PROPN
bionys-568	291	23	,	,	PUNCT
bionys-568	291	24	chan	chan	PROPN
bionys-568	291	25	,	,	PUNCT
bionys-568	291	26	h.l	h.l	PROPN
bionys-568	291	27	.	.	PROPN
bionys-568	291	28	,	,	PUNCT
bionys-568	291	29	&	&	CCONJ
bionys-568	291	30	lok	lok	PROPN
bionys-568	291	31	,	,	PUNCT
bionys-568	291	32	a.	a.	NOUN
bionys-568	291	33	(	(	PUNCT
bionys-568	291	34	2014	2014	NUM
bionys-568	291	35	)	)	PUNCT
bionys-568	291	36	.	.	PUNCT
bionys-568	292	1	hepatitis	hepatitis	PROPN
bionys-568	292	2	b	b	PROPN
bionys-568	292	3	virus	virus	NOUN
bionys-568	292	4	infection	infection	NOUN
bionys-568	292	5	.	.	PUNCT
bionys-568	293	1	the	the	DET
bionys-568	293	2	lancet	lancet	PROPN
bionys-568	293	3	,	,	PUNCT
bionys-568	293	4	384(9959	384(9959	NUM
bionys-568	293	5	)	)	PUNCT
bionys-568	293	6	,	,	PUNCT
bionys-568	293	7	2053.doi	2053.doi	NUM
bionys-568	293	8	:	:	PUNCT
bionys-568	293	9	10.1016	10.1016	NUM
bionys-568	293	10	/	/	SYM
bionys-568	293	11	s0140	s0140	PROPN
bionys-568	293	12	-	-	PUNCT
bionys-568	293	13	6736(14)60220	6736(14)60220	ADP
bionys-568	293	14	-	-	PUNCT
bionys-568	293	15	8	8	NUM
bionys-568	293	16	‏.2063	‏.2063	NOUN
bionys-568	293	17	watson	watson	PROPN
bionys-568	293	18	,	,	PUNCT
bionys-568	293	19	s.	s.	PROPN
bionys-568	293	20	,	,	PUNCT
bionys-568	293	21	gallagher	gallagher	PROPN
bionys-568	293	22	,	,	PUNCT
bionys-568	293	23	p.	p.	NOUN
bionys-568	293	24	,	,	PUNCT
bionys-568	293	25	porter	porter	NOUN
bionys-568	293	26	,	,	PUNCT
bionys-568	293	27	r.j	r.j	PROPN
bionys-568	293	28	.	.	PROPN
bionys-568	293	29	,	,	PUNCT
bionys-568	293	30	smith	smith	PROPN
bionys-568	293	31	,	,	PUNCT
bionys-568	293	32	m.s	m.s	PROPN
bionys-568	293	33	.	.	PROPN
bionys-568	293	34	,	,	PUNCT
bionys-568	293	35	herron	herron	PROPN
bionys-568	293	36	,	,	PUNCT
bionys-568	293	37	l.j	l.j	PROPN
bionys-568	293	38	.	.	PROPN
bionys-568	293	39	,	,	PUNCT
bionys-568	293	40	bulmer	bulmer	PROPN
bionys-568	293	41	,	,	PUNCT
bionys-568	293	42	s.	s.	PROPN
bionys-568	293	43	,	,	PUNCT
bionys-568	293	44	...	...	PUNCT
bionys-568	293	45	&	&	CCONJ
bionys-568	293	46	north296	north296	PROPN
bionys-568	293	47	biologica	biologica	PROPN
bionys-568	293	48	nyssana	nyssana	PROPN
bionys-568	293	49	●	●	PUNCT
bionys-568	293	50	16	16	NUM
bionys-568	293	51	(	(	PUNCT
bionys-568	293	52	1	1	NUM
bionys-568	293	53	)	)	PUNCT
bionys-568	293	54	june	june	PROPN
bionys-568	293	55	2025	2025	NUM
bionys-568	293	56	:	:	PUNCT
bionys-568	293	57	287	287	NUM
bionys-568	293	58	-	-	SYM
bionys-568	293	59	296	296	NUM
bionys-568	293	60	al	al	PROPN
bionys-568	293	61	-	-	PUNCT
bionys-568	293	62	khaykanee	khaykanee	PROPN
bionys-568	293	63	et	et	PROPN
bionys-568	293	64	al	al	PROPN
bionys-568	293	65	.	.	PUNCT
bionys-568	294	1	●	●	PUNCT
bionys-568	294	2	role	role	NOUN
bionys-568	294	3	of	of	ADP
bionys-568	294	4	11β	11β	PROPN
bionys-568	294	5	-	-	PUNCT
bionys-568	294	6	hydroxysteroid	hydroxysteroid	VERB
bionys-568	294	7	dehydrogenase	dehydrogenase	NOUN
bionys-568	294	8	gene	gene	NOUN
bionys-568	294	9	polymorphisms	polymorphism	NOUN
bionys-568	294	10	rs846910	rs846910	NOUN
bionys-568	294	11	and	and	CCONJ
bionys-568	294	12	rs12086634	rs12086634	PROPN
bionys-568	294	13	in	in	ADP
bionys-568	294	14	the	the	DET
bionys-568	294	15	etiology	etiology	NOUN
bionys-568	294	16	of	of	ADP
bionys-568	294	17	hepatocellular	hepatocellular	ADJ
bionys-568	294	18	carcinoma	carcinoma	NOUN
bionys-568	294	19	east	east	ADJ
bionys-568	294	20	mood	mood	NOUN
bionys-568	294	21	disorders	disorder	NOUN
bionys-568	294	22	clinical	clinical	ADJ
bionys-568	294	23	research	research	NOUN
bionys-568	294	24	group	group	NOUN
bionys-568	294	25	.	.	PUNCT
bionys-568	295	1	(	(	PUNCT
bionys-568	295	2	2012	2012	NUM
bionys-568	295	3	)	)	PUNCT
bionys-568	295	4	.	.	PUNCT
bionys-568	296	1	a	a	DET
bionys-568	296	2	randomized	randomized	ADJ
bionys-568	296	3	trial	trial	NOUN
bionys-568	296	4	to	to	PART
bionys-568	296	5	examine	examine	VERB
bionys-568	296	6	the	the	DET
bionys-568	296	7	effect	effect	NOUN
bionys-568	296	8	of	of	ADP
bionys-568	296	9	mifepristone	mifepristone	NOUN
bionys-568	296	10	on	on	ADP
bionys-568	296	11	neuropsychological	neuropsychological	ADJ
bionys-568	296	12	performance	performance	NOUN
bionys-568	296	13	and	and	CCONJ
bionys-568	296	14	mood	mood	NOUN
bionys-568	296	15	in	in	ADP
bionys-568	296	16	patients	patient	NOUN
bionys-568	296	17	with	with	ADP
bionys-568	296	18	bipolar	bipolar	ADJ
bionys-568	296	19	depression	depression	NOUN
bionys-568	296	20	.	.	PUNCT
bionys-568	297	1	biological	biological	ADJ
bionys-568	297	2	psychiatry	psychiatry	NOUN
bionys-568	297	3	,	,	PUNCT
bionys-568	297	4	72(11	72(11	NUM
bionys-568	297	5	)	)	PUNCT
bionys-568	297	6	,	,	PUNCT
bionys-568	297	7	943	943	NUM
bionys-568	297	8	-	-	SYM
bionys-568	297	9	949.‏	949.‏	NUM
bionys-568	297	10	doi	doi	NOUN
bionys-568	297	11	:	:	PUNCT
bionys-568	297	12	10.1016	10.1016	NUM
bionys-568	297	13	/	/	SYM
bionys-568	297	14	j.biopsych.2012.05.029	j.biopsych.2012.05.029	PROPN
bionys-568	297	15	.	.	PUNCT