id	sid	tid	token	lemma	pos
bionys-641	1	1	liana	liana	VERB
bionys-641	1	2	et	et	PROPN
bionys-641	1	3	al	al	PROPN
bionys-641	1	4	.	.	PROPN
bionys-641	1	5	2025	2025	NUM
bionys-641	1	6	,	,	PUNCT
bionys-641	1	7	biologica	biologica	PROPN
bionys-641	1	8	nyssana	nyssana	PROPN
bionys-641	1	9	16(2	16(2	NUM
bionys-641	1	10	)	)	PUNCT
bionys-641	1	11	16	16	NUM
bionys-641	1	12	(	(	PUNCT
bionys-641	1	13	2	2	NUM
bionys-641	1	14	)	)	PUNCT
bionys-641	1	15	december	december	PROPN
bionys-641	1	16	2025	2025	NUM
bionys-641	1	17	:	:	PUNCT
bionys-641	1	18	doi	doi	NOUN
bionys-641	1	19	:	:	PUNCT
bionys-641	1	20	10.46793	10.46793	NUM
bionys-641	1	21	/	/	SYM
bionys-641	1	22	biolnyss.16.2.8l	biolnyss.16.2.8l	NOUN
bionys-641	1	23	cell	cell	NOUN
bionys-641	1	24	deaths	death	NOUN
bionys-641	1	25	and	and	CCONJ
bionys-641	1	26	their	their	PRON
bionys-641	1	27	associated	associate	VERB
bionys-641	1	28	mechanisms	mechanism	NOUN
bionys-641	1	29	original	original	ADJ
bionys-641	1	30	article	article	NOUN
bionys-641	1	31	phey	phey	PROPN
bionys-641	1	32	liana	liana	PROPN
bionys-641	1	33	department	department	PROPN
bionys-641	1	34	of	of	ADP
bionys-641	1	35	clinical	clinical	ADJ
bionys-641	1	36	pathology	pathology	NOUN
bionys-641	1	37	,	,	PUNCT
bionys-641	1	38	faculty	faculty	NOUN
bionys-641	1	39	of	of	ADP
bionys-641	1	40	medicine	medicine	NOUN
bionys-641	1	41	,	,	PUNCT
bionys-641	1	42	universitas	universita	NOUN
bionys-641	1	43	sriwijaya	sriwijaya	PROPN
bionys-641	1	44	-	-	PUNCT
bionys-641	1	45	rsup	rsup	PROPN
bionys-641	1	46	dr	dr	PROPN
bionys-641	1	47	.	.	PROPN
bionys-641	1	48	mohammad	mohammad	PROPN
bionys-641	1	49	hoesin	hoesin	PROPN
bionys-641	1	50	,	,	PUNCT
bionys-641	1	51	palembang	palembang	PROPN
bionys-641	1	52	,	,	PUNCT
bionys-641	1	53	indonesia	indonesia	PROPN
bionys-641	1	54	pheyliana@fk.unsri.ac.id	pheyliana@fk.unsri.ac.id	PROPN
bionys-641	1	55	(	(	PUNCT
bionys-641	1	56	corresponding	corresponding	ADJ
bionys-641	1	57	author	author	NOUN
bionys-641	1	58	)	)	PUNCT
bionys-641	1	59	masagus	masagus	PROPN
bionys-641	1	60	irsan	irsan	PROPN
bionys-641	1	61	saleh	saleh	PROPN
bionys-641	1	62	department	department	PROPN
bionys-641	1	63	of	of	ADP
bionys-641	1	64	pharmacology	pharmacology	NOUN
bionys-641	1	65	,	,	PUNCT
bionys-641	1	66	faculty	faculty	NOUN
bionys-641	1	67	of	of	ADP
bionys-641	1	68	medicine	medicine	NOUN
bionys-641	1	69	,	,	PUNCT
bionys-641	1	70	universitas	universita	NOUN
bionys-641	1	71	sriwijaya	sriwijaya	PROPN
bionys-641	1	72	,	,	PUNCT
bionys-641	1	73	palembang	palembang	PROPN
bionys-641	1	74	,	,	PUNCT
bionys-641	1	75	indonesia	indonesia	PROPN
bionys-641	1	76	desi	desi	PROPN
bionys-641	1	77	oktariana	oktariana	PROPN
bionys-641	1	78	department	department	PROPN
bionys-641	1	79	of	of	ADP
bionys-641	1	80	physiology	physiology	NOUN
bionys-641	1	81	,	,	PUNCT
bionys-641	1	82	faculty	faculty	NOUN
bionys-641	1	83	of	of	ADP
bionys-641	1	84	medicine	medicine	NOUN
bionys-641	1	85	,	,	PUNCT
bionys-641	1	86	universitas	universita	NOUN
bionys-641	1	87	sriwijaya	sriwijaya	PROPN
bionys-641	1	88	,	,	PUNCT
bionys-641	1	89	palembang	palembang	PROPN
bionys-641	1	90	,	,	PUNCT
bionys-641	1	91	indonesia	indonesia	PROPN
bionys-641	1	92	tungki	tungki	PROPN
bionys-641	1	93	pratama	pratama	PROPN
bionys-641	1	94	umar	umar	PROPN
bionys-641	1	95	division	division	NOUN
bionys-641	1	96	of	of	ADP
bionys-641	1	97	surgery	surgery	NOUN
bionys-641	1	98	and	and	CCONJ
bionys-641	1	99	interventional	interventional	ADJ
bionys-641	1	100	science	science	NOUN
bionys-641	1	101	,	,	PUNCT
bionys-641	1	102	faculty	faculty	NOUN
bionys-641	1	103	of	of	ADP
bionys-641	1	104	medicine	medicine	NOUN
bionys-641	1	105	,	,	PUNCT
bionys-641	1	106	university	university	NOUN
bionys-641	1	107	college	college	PROPN
bionys-641	1	108	london	london	PROPN
bionys-641	1	109	,	,	PUNCT
bionys-641	1	110	london	london	PROPN
bionys-641	1	111	,	,	PUNCT
bionys-641	1	112	uk	uk	PROPN
bionys-641	1	113	received	receive	VERB
bionys-641	1	114	:	:	PUNCT
bionys-641	1	115	june	june	PROPN
bionys-641	1	116	29	29	NUM
bionys-641	1	117	,	,	PUNCT
bionys-641	1	118	2025	2025	NUM
bionys-641	1	119	revised	revise	VERB
bionys-641	1	120	:	:	PUNCT
bionys-641	1	121	september	september	PROPN
bionys-641	1	122	04	04	NUM
bionys-641	1	123	,	,	PUNCT
bionys-641	1	124	2025	2025	NUM
bionys-641	1	125	accepted	accept	VERB
bionys-641	1	126	:	:	PUNCT
bionys-641	1	127	september	september	PROPN
bionys-641	1	128	04	04	NUM
bionys-641	1	129	,	,	PUNCT
bionys-641	1	130	2025	2025	NUM
bionys-641	1	131	abstract	abstract	NOUN
bionys-641	1	132	:	:	PUNCT
bionys-641	1	133	cell	cell	NOUN
bionys-641	1	134	death	death	NOUN
bionys-641	1	135	is	be	AUX
bionys-641	1	136	a	a	DET
bionys-641	1	137	crucial	crucial	ADJ
bionys-641	1	138	process	process	NOUN
bionys-641	1	139	in	in	ADP
bionys-641	1	140	every	every	DET
bionys-641	1	141	organism	organism	NOUN
bionys-641	1	142	,	,	PUNCT
bionys-641	1	143	maintaining	maintain	VERB
bionys-641	1	144	a	a	DET
bionys-641	1	145	balance	balance	NOUN
bionys-641	1	146	between	between	ADP
bionys-641	1	147	the	the	DET
bionys-641	1	148	number	number	NOUN
bionys-641	1	149	of	of	ADP
bionys-641	1	150	new	new	ADJ
bionys-641	1	151	cells	cell	NOUN
bionys-641	1	152	generated	generate	VERB
bionys-641	1	153	through	through	ADP
bionys-641	1	154	mitosis	mitosis	NOUN
bionys-641	1	155	and	and	CCONJ
bionys-641	1	156	the	the	DET
bionys-641	1	157	number	number	NOUN
bionys-641	1	158	of	of	ADP
bionys-641	1	159	damaged	damaged	ADJ
bionys-641	1	160	or	or	CCONJ
bionys-641	1	161	unnecessary	unnecessary	ADJ
bionys-641	1	162	cells	cell	NOUN
bionys-641	1	163	removed	remove	VERB
bionys-641	1	164	from	from	ADP
bionys-641	1	165	the	the	DET
bionys-641	1	166	body	body	NOUN
bionys-641	1	167	.	.	PUNCT
bionys-641	2	1	it	it	PRON
bionys-641	2	2	happens	happen	VERB
bionys-641	2	3	from	from	ADP
bionys-641	2	4	the	the	DET
bionys-641	2	5	embryonic	embryonic	ADJ
bionys-641	2	6	process	process	NOUN
bionys-641	2	7	throughout	throughout	ADP
bionys-641	2	8	every	every	DET
bionys-641	2	9	life	life	NOUN
bionys-641	2	10	stage	stage	NOUN
bionys-641	2	11	of	of	ADP
bionys-641	2	12	a	a	DET
bionys-641	2	13	human	human	ADJ
bionys-641	2	14	being	being	NOUN
bionys-641	2	15	.	.	PUNCT
bionys-641	3	1	regulated	regulated	ADJ
bionys-641	3	2	cell	cell	NOUN
bionys-641	3	3	death	death	NOUN
bionys-641	3	4	,	,	PUNCT
bionys-641	3	5	known	know	VERB
bionys-641	3	6	as	as	ADP
bionys-641	3	7	apoptosis	apoptosis	NOUN
bionys-641	3	8	,	,	PUNCT
bionys-641	3	9	is	be	AUX
bionys-641	3	10	the	the	DET
bionys-641	3	11	most	most	ADV
bionys-641	3	12	common	common	ADJ
bionys-641	3	13	form	form	NOUN
bionys-641	3	14	,	,	PUNCT
bionys-641	3	15	while	while	SCONJ
bionys-641	3	16	accidental	accidental	ADJ
bionys-641	3	17	or	or	CCONJ
bionys-641	3	18	uncontrolled	uncontrolled	ADJ
bionys-641	3	19	cell	cell	NOUN
bionys-641	3	20	death	death	NOUN
bionys-641	3	21	,	,	PUNCT
bionys-641	3	22	known	know	VERB
bionys-641	3	23	as	as	ADP
bionys-641	3	24	necrosis	necrosis	NOUN
bionys-641	3	25	,	,	PUNCT
bionys-641	3	26	is	be	AUX
bionys-641	3	27	associated	associate	VERB
bionys-641	3	28	with	with	ADP
bionys-641	3	29	pathological	pathological	ADJ
bionys-641	3	30	processes	process	NOUN
bionys-641	3	31	.	.	PUNCT
bionys-641	4	1	in	in	ADP
bionys-641	4	2	addition	addition	NOUN
bionys-641	4	3	to	to	ADP
bionys-641	4	4	these	these	DET
bionys-641	4	5	types	type	NOUN
bionys-641	4	6	of	of	ADP
bionys-641	4	7	cell	cell	NOUN
bionys-641	4	8	death	death	NOUN
bionys-641	4	9	,	,	PUNCT
bionys-641	4	10	there	there	PRON
bionys-641	4	11	are	be	VERB
bionys-641	4	12	numerous	numerous	ADJ
bionys-641	4	13	other	other	ADJ
bionys-641	4	14	types	type	NOUN
bionys-641	4	15	,	,	PUNCT
bionys-641	4	16	including	include	VERB
bionys-641	4	17	necroptosis	necroptosis	NOUN
bionys-641	4	18	(	(	PUNCT
bionys-641	4	19	a	a	DET
bionys-641	4	20	controlled	control	VERB
bionys-641	4	21	cell	cell	NOUN
bionys-641	4	22	death	death	NOUN
bionys-641	4	23	with	with	ADP
bionys-641	4	24	an	an	DET
bionys-641	4	25	inflammatory	inflammatory	ADJ
bionys-641	4	26	process	process	NOUN
bionys-641	4	27	)	)	PUNCT
bionys-641	4	28	and	and	CCONJ
bionys-641	4	29	autophagy	autophagy	NOUN
bionys-641	4	30	(	(	PUNCT
bionys-641	4	31	mainly	mainly	ADV
bionys-641	4	32	a	a	DET
bionys-641	4	33	part	part	NOUN
bionys-641	4	34	of	of	ADP
bionys-641	4	35	the	the	DET
bionys-641	4	36	immune	immune	ADJ
bionys-641	4	37	process	process	NOUN
bionys-641	4	38	)	)	PUNCT
bionys-641	4	39	.	.	PUNCT
bionys-641	5	1	it	it	PRON
bionys-641	5	2	is	be	AUX
bionys-641	5	3	important	important	ADJ
bionys-641	5	4	to	to	PART
bionys-641	5	5	note	note	VERB
bionys-641	5	6	that	that	SCONJ
bionys-641	5	7	inhibition	inhibition	NOUN
bionys-641	5	8	of	of	ADP
bionys-641	5	9	regulated	regulated	ADJ
bionys-641	5	10	cell	cell	NOUN
bionys-641	5	11	death	death	NOUN
bionys-641	5	12	can	can	AUX
bionys-641	5	13	impact	impact	VERB
bionys-641	5	14	the	the	DET
bionys-641	5	15	normal	normal	ADJ
bionys-641	5	16	cell	cell	NOUN
bionys-641	5	17	cycle	cycle	NOUN
bionys-641	5	18	and	and	CCONJ
bionys-641	5	19	can	can	AUX
bionys-641	5	20	lead	lead	VERB
bionys-641	5	21	to	to	ADP
bionys-641	5	22	drug	drug	NOUN
bionys-641	5	23	resistance	resistance	NOUN
bionys-641	5	24	.	.	PUNCT
bionys-641	6	1	a	a	DET
bionys-641	6	2	classic	classic	ADJ
bionys-641	6	3	example	example	NOUN
bionys-641	6	4	of	of	ADP
bionys-641	6	5	dysfunctional	dysfunctional	ADJ
bionys-641	6	6	cell	cell	NOUN
bionys-641	6	7	death	death	NOUN
bionys-641	6	8	regulation	regulation	NOUN
bionys-641	6	9	is	be	AUX
bionys-641	6	10	cancer	cancer	NOUN
bionys-641	6	11	development	development	NOUN
bionys-641	6	12	.	.	PUNCT
bionys-641	7	1	this	this	DET
bionys-641	7	2	review	review	NOUN
bionys-641	7	3	summarizes	summarize	VERB
bionys-641	7	4	cell	cell	NOUN
bionys-641	7	5	death	death	NOUN
bionys-641	7	6	types	type	NOUN
bionys-641	7	7	and	and	CCONJ
bionys-641	7	8	their	their	PRON
bionys-641	7	9	associated	associated	ADJ
bionys-641	7	10	mechanisms	mechanism	NOUN
bionys-641	7	11	.	.	PUNCT
bionys-641	8	1	key	key	ADJ
bionys-641	8	2	words	word	NOUN
bionys-641	8	3	:	:	PUNCT
bionys-641	8	4	accidental	accidental	ADJ
bionys-641	8	5	cell	cell	NOUN
bionys-641	8	6	death	death	NOUN
bionys-641	8	7	,	,	PUNCT
bionys-641	8	8	apoptosis	apoptosis	NOUN
bionys-641	8	9	,	,	PUNCT
bionys-641	8	10	necrosis	necrosis	NOUN
bionys-641	8	11	,	,	PUNCT
bionys-641	8	12	regulated	regulated	ADJ
bionys-641	8	13	cell	cell	NOUN
bionys-641	8	14	death	death	NOUN
bionys-641	8	15	apstrakt	apstrakt	NOUN
bionys-641	8	16	:	:	PUNCT
bionys-641	8	17	ćelijske	ćelijske	PROPN
bionys-641	8	18	smrti	smrti	PROPN
bionys-641	8	19	mehanizmi	mehanizmi	PROPN
bionys-641	8	20	udruženi	udruženi	PROPN
bionys-641	8	21	sa	sa	PROPN
bionys-641	8	22	njima	njima	PROPN
bionys-641	8	23	ćelijska	ćelijska	PROPN
bionys-641	8	24	smrt	smrt	PROPN
bionys-641	8	25	je	je	PROPN
bionys-641	8	26	ključni	ključni	PROPN
bionys-641	8	27	proces	proces	PROPN
bionys-641	8	28	u	u	PROPN
bionys-641	8	29	svakom	svakom	NOUN
bionys-641	8	30	organizmu	organizmu	VERB
bionys-641	8	31	,	,	PUNCT
bionys-641	8	32	jer	jer	PROPN
bionys-641	8	33	održava	održava	PROPN
bionys-641	8	34	ravnotežu	ravnotežu	PROPN
bionys-641	8	35	između	između	VERB
bionys-641	8	36	broja	broja	NOUN
bionys-641	8	37	novih	novih	VERB
bionys-641	8	38	ćelija	ćelija	ADJ
bionys-641	8	39	nastalih	nastalih	ADJ
bionys-641	8	40	mitozom	mitozom	NOUN
bionys-641	9	1	i	i	PRON
bionys-641	9	2	broja	broja	VERB
bionys-641	9	3	oštećenih	oštećenih	PROPN
bionys-641	9	4	ili	ili	PROPN
bionys-641	9	5	nepotrebnih	nepotrebnih	PROPN
bionys-641	9	6	ćelija	ćelija	PROPN
bionys-641	9	7	uklonjenih	uklonjenih	PROPN
bionys-641	10	1	iz	iz	INTJ
bionys-641	10	2	organizma	organizma	PROPN
bionys-641	10	3	.	.	PUNCT
bionys-641	11	1	ona	ona	PROPN
bionys-641	11	2	se	se	PROPN
bionys-641	11	3	odvija	odvija	PROPN
bionys-641	11	4	od	od	PROPN
bionys-641	11	5	embrionalnog	embrionalnog	PROPN
bionys-641	11	6	razvoja	razvoja	PROPN
bionys-641	11	7	pa	pa	PROPN
bionys-641	11	8	tokom	tokom	PROPN
bionys-641	11	9	svih	svih	PROPN
bionys-641	11	10	životnih	životnih	PROPN
bionys-641	11	11	stadijuma	stadijuma	PROPN
bionys-641	11	12	čoveka	čoveka	PROPN
bionys-641	11	13	.	.	PUNCT
bionys-641	12	1	regulisana	regulisana	PROPN
bionys-641	12	2	ćelijska	ćelijska	PROPN
bionys-641	12	3	smrt	smrt	PROPN
bionys-641	12	4	,	,	PUNCT
bionys-641	12	5	poznata	poznata	NOUN
bionys-641	12	6	kao	kao	PROPN
bionys-641	12	7	apoptoza	apoptoza	PROPN
bionys-641	12	8	,	,	PUNCT
bionys-641	12	9	predstavlja	predstavlja	PROPN
bionys-641	12	10	najčešći	najčešći	PROPN
bionys-641	12	11	oblik	oblik	PROPN
bionys-641	12	12	,	,	PUNCT
bionys-641	12	13	dok	dok	PROPN
bionys-641	12	14	je	je	PROPN
bionys-641	12	15	slučajna	slučajna	PROPN
bionys-641	12	16	ili	ili	PROPN
bionys-641	12	17	nekontrolisana	nekontrolisana	PROPN
bionys-641	12	18	ćelijska	ćelijska	PROPN
bionys-641	12	19	smrt	smrt	PROPN
bionys-641	12	20	,	,	PUNCT
bionys-641	12	21	poznata	poznata	NOUN
bionys-641	12	22	kao	kao	PROPN
bionys-641	12	23	nekroza	nekroza	PROPN
bionys-641	12	24	,	,	PUNCT
bionys-641	12	25	povezana	povezana	PROPN
bionys-641	12	26	sa	sa	PROPN
bionys-641	12	27	patološkim	patološkim	PROPN
bionys-641	12	28	procesima	procesima	PROPN
bionys-641	12	29	.	.	PUNCT
bionys-641	13	1	pored	pore	VERB
bionys-641	13	2	ovih	ovih	ADJ
bionys-641	13	3	oblika	oblika	ADJ
bionys-641	13	4	ćelijske	ćelijske	PROPN
bionys-641	13	5	smrti	smrti	PROPN
bionys-641	13	6	,	,	PUNCT
bionys-641	13	7	postoji	postoji	NOUN
bionys-641	13	8	i	i	PRON
bionys-641	13	9	niz	niz	PROPN
bionys-641	13	10	drugih	drugih	PROPN
bionys-641	13	11	tipova	tipova	PROPN
bionys-641	13	12	,	,	PUNCT
bionys-641	13	13	uključujući	uključujući	ADV
bionys-641	13	14	nekroptozu	nekroptozu	PROPN
bionys-641	13	15	(	(	PUNCT
bionys-641	13	16	regulisanu	regulisanu	PROPN
bionys-641	13	17	ćelijsku	ćelijsku	PROPN
bionys-641	13	18	smrt	smrt	PROPN
bionys-641	13	19	sa	sa	PROPN
bionys-641	13	20	inflamatornim	inflamatornim	PROPN
bionys-641	13	21	procesom	procesom	NOUN
bionys-641	13	22	)	)	PUNCT
bionys-641	14	1	i	i	PRON
bionys-641	14	2	autofagiju	autofagiju	ADV
bionys-641	14	3	(	(	PUNCT
bionys-641	14	4	uglavnom	uglavnom	VERB
bionys-641	14	5	deo	deo	NOUN
bionys-641	14	6	imunskog	imunskog	NOUN
bionys-641	14	7	procesa	procesa	PROPN
bionys-641	14	8	)	)	PUNCT
bionys-641	14	9	.	.	PUNCT
bionys-641	15	1	važno	važno	PROPN
bionys-641	15	2	je	je	PROPN
bionys-641	15	3	napomenuti	napomenuti	PROPN
bionys-641	15	4	da	da	PROPN
bionys-641	15	5	inhibicija	inhibicija	PROPN
bionys-641	15	6	regulisane	regulisane	PROPN
bionys-641	15	7	ćelijske	ćelijske	PROPN
bionys-641	15	8	smrti	smrti	PROPN
bionys-641	15	9	može	može	PROPN
bionys-641	15	10	uticati	uticati	NOUN
bionys-641	15	11	na	na	PROPN
bionys-641	15	12	normalan	normalan	PROPN
bionys-641	15	13	ćelijski	ćelijski	PROPN
bionys-641	15	14	ciklus	ciklus	PROPN
bionys-641	16	1	i	i	PRON
bionys-641	16	2	dovesti	dovesti	NOUN
bionys-641	16	3	do	do	AUX
bionys-641	16	4	rezistencije	rezistencije	VERB
bionys-641	16	5	na	na	PART
bionys-641	16	6	lekove	lekove	VERB
bionys-641	16	7	.	.	PUNCT
bionys-641	17	1	klasičan	klasičan	PROPN
bionys-641	17	2	primer	primer	NOUN
bionys-641	17	3	disfunkcionalne	disfunkcionalne	PROPN
bionys-641	17	4	regulacije	regulacije	NOUN
bionys-641	17	5	ćelijske	ćelijske	PROPN
bionys-641	17	6	smrti	smrti	PROPN
bionys-641	17	7	jeste	jeste	PROPN
bionys-641	17	8	razvoj	razvoj	PROPN
bionys-641	17	9	kancera	kancera	PROPN
bionys-641	17	10	.	.	PUNCT
bionys-641	18	1	ovaj	ovaj	PROPN
bionys-641	18	2	pregled	pregle	VERB
bionys-641	18	3	sumira	sumira	NOUN
bionys-641	18	4	tipove	tipove	PROPN
bionys-641	18	5	ćelijske	ćelijske	PROPN
bionys-641	18	6	smrti	smrti	PROPN
bionys-641	19	1	i	i	PRON
bionys-641	19	2	njihove	njihove	VERB
bionys-641	19	3	povezane	povezane	PROPN
bionys-641	19	4	mehanizme	mehanizme	NOUN
bionys-641	19	5	.	.	PUNCT
bionys-641	20	1	ključne	ključne	PROPN
bionys-641	20	2	reči	reči	NOUN
bionys-641	20	3	:	:	PUNCT
bionys-641	20	4	slučajna	slučajna	PROPN
bionys-641	20	5	ćelijska	ćelijska	PROPN
bionys-641	20	6	smrt	smrt	PROPN
bionys-641	20	7	,	,	PUNCT
bionys-641	20	8	apoptoza	apoptoza	PROPN
bionys-641	20	9	,	,	PUNCT
bionys-641	20	10	nekroza	nekroza	PROPN
bionys-641	20	11	,	,	PUNCT
bionys-641	20	12	regulisana	regulisana	PROPN
bionys-641	20	13	ćelijska	ćelijska	PROPN
bionys-641	20	14	smrt	smrt	PROPN
bionys-641	20	15	introduction	introduction	NOUN
bionys-641	20	16	every	every	DET
bionys-641	20	17	organism	organism	NOUN
bionys-641	20	18	,	,	PUNCT
bionys-641	20	19	either	either	CCONJ
bionys-641	20	20	multicellular	multicellular	ADJ
bionys-641	20	21	and	and	CCONJ
bionys-641	20	22	unicellular	unicellular	ADJ
bionys-641	20	23	,	,	PUNCT
bionys-641	20	24	has	have	VERB
bionys-641	20	25	a	a	DET
bionys-641	20	26	specific	specific	ADJ
bionys-641	20	27	mechanism	mechanism	NOUN
bionys-641	20	28	to	to	PART
bionys-641	20	29	preserve	preserve	VERB
bionys-641	20	30	a	a	DET
bionys-641	20	31	homeostatic	homeostatic	ADJ
bionys-641	20	32	state	state	NOUN
bionys-641	20	33	between	between	ADP
bionys-641	20	34	the	the	DET
bionys-641	20	35	amount	amount	NOUN
bionys-641	20	36	of	of	ADP
bionys-641	20	37	new	new	ADJ
bionys-641	20	38	cells	cell	NOUN
bionys-641	20	39	that	that	PRON
bionys-641	20	40	emerged	emerge	VERB
bionys-641	20	41	through	through	ADP
bionys-641	20	42	mitosis	mitosis	NOUN
bionys-641	20	43	and	and	CCONJ
bionys-641	20	44	the	the	DET
bionys-641	20	45	number	number	NOUN
bionys-641	20	46	of	of	ADP
bionys-641	20	47	damaged	damaged	ADJ
bionys-641	20	48	or	or	CCONJ
bionys-641	20	49	unfavorable	unfavorable	ADJ
bionys-641	20	50	cells	cell	NOUN
bionys-641	20	51	that	that	PRON
bionys-641	20	52	need	need	VERB
bionys-641	20	53	to	to	PART
bionys-641	20	54	be	be	AUX
bionys-641	20	55	eliminated	eliminate	VERB
bionys-641	20	56	from	from	ADP
bionys-641	20	57	the	the	DET
bionys-641	20	58	organism	organism	NOUN
bionys-641	20	59	’s	’s	PART
bionys-641	20	60	body	body	NOUN
bionys-641	20	61	(	(	PUNCT
bionys-641	20	62	spiesser	spiesser	NOUN
bionys-641	20	63	et	et	PROPN
bionys-641	20	64	al	al	PROPN
bionys-641	20	65	.	.	PROPN
bionys-641	20	66	,	,	PUNCT
bionys-641	20	67	2012	2012	NUM
bionys-641	20	68	;	;	PUNCT
bionys-641	20	69	alvarado	alvarado	PROPN
bionys-641	20	70	et	et	PROPN
bionys-641	20	71	al	al	PROPN
bionys-641	20	72	.	.	PROPN
bionys-641	20	73	,	,	PUNCT
bionys-641	20	74	2018	2018	NUM
bionys-641	20	75	)	)	PUNCT
bionys-641	20	76	.	.	PUNCT
bionys-641	21	1	continuous	continuous	ADJ
bionys-641	21	2	cell	cell	NOUN
bionys-641	21	3	turnover	turnover	NOUN
bionys-641	21	4	is	be	AUX
bionys-641	21	5	essential	essential	ADJ
bionys-641	21	6	to	to	PART
bionys-641	21	7	produce	produce	VERB
bionys-641	21	8	physical	physical	ADJ
bionys-641	21	9	features	feature	NOUN
bionys-641	21	10	that	that	PRON
bionys-641	21	11	consist	consist	VERB
bionys-641	21	12	of	of	ADP
bionys-641	21	13	fingers	finger	NOUN
bionys-641	21	14	and	and	CCONJ
bionys-641	21	15	toes	toe	NOUN
bionys-641	21	16	,	,	PUNCT
bionys-641	21	17	which	which	PRON
bionys-641	21	18	emerge	emerge	VERB
bionys-641	21	19	after	after	ADP
bionys-641	21	20	developing	develop	VERB
bionys-641	21	21	from	from	ADP
bionys-641	21	22	the	the	DET
bionys-641	21	23	webbed	webbed	NOUN
bionys-641	21	24	limbs	limb	NOUN
bionys-641	21	25	first	first	ADV
bionys-641	21	26	noticed	notice	VERB
bionys-641	21	27	in	in	ADP
bionys-641	21	28	the	the	DET
bionys-641	21	29	human	human	ADJ
bionys-641	21	30	fetus	fetus	NOUN
bionys-641	21	31	,	,	PUNCT
bionys-641	21	32	observed	observe	VERB
bionys-641	21	33	around	around	ADP
bionys-641	21	34	week	week	NOUN
bionys-641	21	35	10	10	NUM
bionys-641	21	36	of	of	ADP
bionys-641	21	37	gestation	gestation	NOUN
bionys-641	21	38	(	(	PUNCT
bionys-641	21	39	hurle	hurle	PROPN
bionys-641	21	40	&	&	CCONJ
bionys-641	21	41	ganan	ganan	PROPN
bionys-641	21	42	,	,	PUNCT
bionys-641	21	43	1986	1986	NUM
bionys-641	21	44	)	)	PUNCT
bionys-641	21	45	.	.	PUNCT
bionys-641	22	1	meanwhile	meanwhile	ADV
bionys-641	22	2	,	,	PUNCT
bionys-641	22	3	uncontrolled	uncontrolled	ADJ
bionys-641	22	4	cellular	cellular	ADJ
bionys-641	22	5	proliferation	proliferation	NOUN
bionys-641	22	6	and	and	CCONJ
bionys-641	22	7	growth	growth	NOUN
bionys-641	22	8	may	may	AUX
bionys-641	22	9	cause	cause	VERB
bionys-641	22	10	the	the	DET
bionys-641	22	11	development	development	NOUN
bionys-641	22	12	of	of	ADP
bionys-641	22	13	several	several	ADJ
bionys-641	22	14	debilitating	debilitate	VERB
bionys-641	22	15	diseases	disease	NOUN
bionys-641	22	16	,	,	PUNCT
bionys-641	22	17	with	with	ADP
bionys-641	22	18	cancer	cancer	NOUN
bionys-641	22	19	as	as	ADP
bionys-641	22	20	the	the	DET
bionys-641	22	21	main	main	ADJ
bionys-641	22	22	example	example	NOUN
bionys-641	22	23	(	(	PUNCT
bionys-641	22	24	feitelson	feitelson	NOUN
bionys-641	22	25	et	et	PROPN
bionys-641	22	26	al	al	PROPN
bionys-641	22	27	.	.	PROPN
bionys-641	22	28	,	,	PUNCT
bionys-641	22	29	2015	2015	NUM
bionys-641	22	30	)	)	PUNCT
bionys-641	22	31	.	.	PUNCT
bionys-641	23	1	in	in	ADP
bionys-641	23	2	contrast	contrast	NOUN
bionys-641	23	3	,	,	PUNCT
bionys-641	23	4	an	an	DET
bionys-641	23	5	extremely	extremely	ADV
bionys-641	23	6	high	high	ADJ
bionys-641	23	7	cell	cell	NOUN
bionys-641	23	8	death	death	NOUN
bionys-641	23	9	rate	rate	NOUN
bionys-641	23	10	can	can	AUX
bionys-641	23	11	lead	lead	VERB
bionys-641	23	12	to	to	ADP
bionys-641	23	13	many	many	ADJ
bionys-641	23	14	disorders	disorder	NOUN
bionys-641	23	15	,	,	PUNCT
bionys-641	23	16	including	include	VERB
bionys-641	23	17	rheumatoid	rheumatoid	NOUN
bionys-641	23	18	arthritis	arthritis	NOUN
bionys-641	23	19	,	,	PUNCT
bionys-641	23	20	alzheimer	alzheimer	PROPN
bionys-641	23	21	's	's	PART
bionys-641	23	22	disease	disease	NOUN
bionys-641	23	23	(	(	PUNCT
bionys-641	23	24	ad	ad	NOUN
bionys-641	23	25	)	)	PUNCT
bionys-641	23	26	,	,	PUNCT
bionys-641	23	27	and	and	CCONJ
bionys-641	23	28	parkinson	parkinson	NOUN
bionys-641	23	29	's	's	PART
bionys-641	23	30	disease	disease	NOUN
bionys-641	23	31	(	(	PUNCT
bionys-641	23	32	gorman	gorman	NOUN
bionys-641	23	33	,	,	PUNCT
bionys-641	23	34	2008	2008	NUM
bionys-641	23	35	;	;	PUNCT
bionys-641	23	36	d’arcy	d’arcy	PROPN
bionys-641	23	37	,	,	PUNCT
bionys-641	23	38	2019	2019	NUM
bionys-641	23	39	)	)	PUNCT
bionys-641	23	40	.	.	PUNCT
bionys-641	24	1	cell	cell	NOUN
bionys-641	24	2	death	death	NOUN
bionys-641	24	3	can	can	AUX
bionys-641	24	4	occur	occur	VERB
bionys-641	24	5	through	through	ADP
bionys-641	24	6	several	several	ADJ
bionys-641	24	7	mechanisms	mechanism	NOUN
bionys-641	24	8	.	.	PUNCT
bionys-641	25	1	it	it	PRON
bionys-641	25	2	can	can	AUX
bionys-641	25	3	happen	happen	VERB
bionys-641	25	4	in	in	ADP
bionys-641	25	5	a	a	DET
bionys-641	25	6	programmed	program	VERB
bionys-641	25	7	(	(	PUNCT
bionys-641	25	8	controlled	control	VERB
bionys-641	25	9	)	)	PUNCT
bionys-641	25	10	way	way	NOUN
bionys-641	25	11	,	,	PUNCT
bionys-641	25	12	encompassing	encompass	VERB
bionys-641	25	13	a	a	DET
bionys-641	25	14	multitude	multitude	NOUN
bionys-641	25	15	of	of	ADP
bionys-641	25	16	biochemical	biochemical	ADJ
bionys-641	25	17	,	,	PUNCT
bionys-641	25	18	physical	physical	ADJ
bionys-641	25	19	,	,	PUNCT
bionys-641	25	20	and	and	CCONJ
bionys-641	25	21	molecular	molecular	ADJ
bionys-641	25	22	operations	operation	NOUN
bionys-641	25	23	,	,	PUNCT
bionys-641	25	24	as	as	ADV
bionys-641	25	25	well	well	ADV
bionys-641	25	26	as	as	ADP
bionys-641	25	27	uncontrolled	uncontrolled	ADJ
bionys-641	25	28	ones	one	NOUN
bionys-641	25	29	,	,	PUNCT
bionys-641	25	30	resulting	result	VERB
bionys-641	25	31	in	in	ADP
bionys-641	25	32	the	the	DET
bionys-641	25	33	leakage	leakage	NOUN
bionys-641	25	34	of	of	ADP
bionys-641	25	35	cell	cell	NOUN
bionys-641	25	36	contents	content	NOUN
bionys-641	25	37	into	into	ADP
bionys-641	25	38	neighboring	neighboring	NOUN
bionys-641	25	39	tissues	tissue	NOUN
bionys-641	25	40	.	.	PUNCT
bionys-641	26	1	these	these	DET
bionys-641	26	2	processes	process	NOUN
bionys-641	26	3	may	may	AUX
bionys-641	26	4	trigger	trigger	VERB
bionys-641	26	5	further	further	ADJ
bionys-641	26	6	inflammatory	inflammatory	ADJ
bionys-641	26	7	response	response	NOUN
bionys-641	26	8	(	(	PUNCT
bionys-641	26	9	particularly	particularly	ADV
bionys-641	26	10	in	in	ADP
bionys-641	26	11	unprogrammed	unprogrammed	ADJ
bionys-641	26	12	cell	cell	NOUN
bionys-641	26	13	death	death	NOUN
bionys-641	26	14	)	)	PUNCT
bionys-641	26	15	or	or	CCONJ
bionys-641	26	16	not	not	PART
bionys-641	26	17	(	(	PUNCT
bionys-641	26	18	fink	fink	PROPN
bionys-641	26	19	&	&	CCONJ
bionys-641	26	20	cookson	cookson	PROPN
bionys-641	26	21	,	,	PUNCT
bionys-641	26	22	2005	2005	NUM
bionys-641	26	23	)	)	PUNCT
bionys-641	26	24	.	.	PUNCT
bionys-641	27	1	apoptosis	apoptosis	NOUN
bionys-641	27	2	,	,	PUNCT
bionys-641	27	3	a	a	DET
bionys-641	27	4	type	type	NOUN
bionys-641	27	5	of	of	ADP
bionys-641	27	6	regulated	regulated	ADJ
bionys-641	27	7	cell	cell	NOUN
bionys-641	27	8	death	death	NOUN
bionys-641	27	9	,	,	PUNCT
bionys-641	27	10	is	be	AUX
bionys-641	27	11	considered	consider	VERB
bionys-641	27	12	as	as	ADP
bionys-641	27	13	the	the	DET
bionys-641	27	14	most	most	ADV
bionys-641	27	15	prevalent	prevalent	ADJ
bionys-641	27	16	type	type	NOUN
bionys-641	27	17	of	of	ADP
bionys-641	27	18	cell	cell	NOUN
bionys-641	27	19	death	death	NOUN
bionys-641	27	20	with	with	ADP
bionys-641	27	21	its	its	PRON
bionys-641	27	22	importance	importance	NOUN
bionys-641	27	23	©	©	ADP
bionys-641	27	24	2025	2025	NUM
bionys-641	27	25	liana	liana	NOUN
bionys-641	27	26	et	et	PROPN
bionys-641	27	27	al	al	PROPN
bionys-641	27	28	.	.	PUNCT
bionys-641	28	1	this	this	PRON
bionys-641	28	2	is	be	AUX
bionys-641	28	3	an	an	DET
bionys-641	28	4	open	open	ADJ
bionys-641	28	5	-	-	PUNCT
bionys-641	28	6	access	access	NOUN
bionys-641	28	7	article	article	NOUN
bionys-641	28	8	distributed	distribute	VERB
bionys-641	28	9	under	under	ADP
bionys-641	28	10	the	the	DET
bionys-641	28	11	terms	term	NOUN
bionys-641	28	12	of	of	ADP
bionys-641	28	13	the	the	DET
bionys-641	28	14	creative	creative	ADJ
bionys-641	28	15	commons	common	NOUN
bionys-641	28	16	attribution	attribution	NOUN
bionys-641	28	17	license	license	NOUN
bionys-641	28	18	,	,	PUNCT
bionys-641	28	19	which	which	PRON
bionys-641	28	20	permits	permit	VERB
bionys-641	28	21	unrestricted	unrestricted	ADJ
bionys-641	28	22	use	use	NOUN
bionys-641	28	23	,	,	PUNCT
bionys-641	28	24	distribution	distribution	NOUN
bionys-641	28	25	,	,	PUNCT
bionys-641	28	26	and	and	CCONJ
bionys-641	28	27	build	build	VERB
bionys-641	28	28	upon	upon	SCONJ
bionys-641	28	29	your	your	PRON
bionys-641	28	30	work	work	NOUN
bionys-641	28	31	non	non	ADJ
bionys-641	28	32	-	-	ADJ
bionys-641	28	33	commercially	commercially	ADV
bionys-641	28	34	under	under	ADP
bionys-641	28	35	the	the	DET
bionys-641	28	36	same	same	ADJ
bionys-641	28	37	license	license	NOUN
bionys-641	28	38	as	as	ADP
bionys-641	28	39	the	the	DET
bionys-641	28	40	original	original	NOUN
bionys-641	28	41	.	.	PUNCT
bionys-641	29	1	throughout	throughout	ADP
bionys-641	29	2	the	the	DET
bionys-641	29	3	body	body	NOUN
bionys-641	29	4	(	(	PUNCT
bionys-641	29	5	d’arcy	d’arcy	PROPN
bionys-641	29	6	,	,	PUNCT
bionys-641	29	7	2019	2019	NUM
bionys-641	29	8	)	)	PUNCT
bionys-641	29	9	.	.	PUNCT
bionys-641	30	1	meanwhile	meanwhile	ADV
bionys-641	30	2	,	,	PUNCT
bionys-641	30	3	the	the	DET
bionys-641	30	4	uncontrolled	uncontrolled	ADJ
bionys-641	30	5	or	or	CCONJ
bionys-641	30	6	accidental	accidental	ADJ
bionys-641	30	7	form	form	NOUN
bionys-641	30	8	of	of	ADP
bionys-641	30	9	cell	cell	NOUN
bionys-641	30	10	death	death	NOUN
bionys-641	30	11	is	be	AUX
bionys-641	30	12	called	call	VERB
bionys-641	30	13	necrosis	necrosis	NOUN
bionys-641	30	14	,	,	PUNCT
bionys-641	30	15	which	which	PRON
bionys-641	30	16	is	be	AUX
bionys-641	30	17	particularly	particularly	ADV
bionys-641	30	18	associated	associate	VERB
bionys-641	30	19	with	with	ADP
bionys-641	30	20	pathological	pathological	ADJ
bionys-641	30	21	processes	process	NOUN
bionys-641	30	22	(	(	PUNCT
bionys-641	30	23	including	include	VERB
bionys-641	30	24	hypoxia	hypoxia	NOUN
bionys-641	30	25	,	,	PUNCT
bionys-641	30	26	microbial	microbial	ADJ
bionys-641	30	27	infection	infection	NOUN
bionys-641	30	28	,	,	PUNCT
bionys-641	30	29	physical	physical	ADJ
bionys-641	30	30	stress	stress	NOUN
bionys-641	30	31	,	,	PUNCT
bionys-641	30	32	and	and	CCONJ
bionys-641	30	33	chemical	chemical	ADJ
bionys-641	30	34	agents	agent	NOUN
bionys-641	30	35	)	)	PUNCT
bionys-641	30	36	(	(	PUNCT
bionys-641	30	37	fathima	fathima	PROPN
bionys-641	30	38	et	et	PROPN
bionys-641	30	39	al	al	PROPN
bionys-641	30	40	.	.	PROPN
bionys-641	30	41	,	,	PUNCT
bionys-641	30	42	2023	2023	NUM
bionys-641	30	43	)	)	PUNCT
bionys-641	30	44	.	.	PUNCT
bionys-641	31	1	the	the	DET
bionys-641	31	2	mechanisms	mechanism	NOUN
bionys-641	31	3	associated	associate	VERB
bionys-641	31	4	with	with	ADP
bionys-641	31	5	mitosis	mitosis	NOUN
bionys-641	31	6	regulation	regulation	NOUN
bionys-641	31	7	(	(	PUNCT
bionys-641	31	8	stimulation	stimulation	NOUN
bionys-641	31	9	or	or	CCONJ
bionys-641	31	10	inhibition	inhibition	NOUN
bionys-641	31	11	)	)	PUNCT
bionys-641	31	12	,	,	PUNCT
bionys-641	31	13	cellular	cellular	ADJ
bionys-641	31	14	abnormality	abnormality	NOUN
bionys-641	31	15	detection	detection	NOUN
bionys-641	31	16	,	,	PUNCT
bionys-641	31	17	and	and	CCONJ
bionys-641	31	18	programmed	program	VERB
bionys-641	31	19	cell	cell	NOUN
bionys-641	31	20	death	death	NOUN
bionys-641	31	21	(	(	PUNCT
bionys-641	31	22	pcd	pcd	NOUN
bionys-641	31	23	)	)	PUNCT
bionys-641	31	24	initiation	initiation	NOUN
bionys-641	31	25	(	(	PUNCT
bionys-641	31	26	apoptosis	apoptosis	NOUN
bionys-641	31	27	,	,	PUNCT
bionys-641	31	28	pyroptosis	pyroptosis	NOUN
bionys-641	31	29	or	or	CCONJ
bionys-641	31	30	autophagy	autophagy	NOUN
bionys-641	31	31	)	)	PUNCT
bionys-641	31	32	in	in	ADP
bionys-641	31	33	animals	animal	NOUN
bionys-641	31	34	involve	involve	VERB
bionys-641	31	35	a	a	DET
bionys-641	31	36	long	long	ADJ
bionys-641	31	37	list	list	NOUN
bionys-641	31	38	of	of	ADP
bionys-641	31	39	regulatory	regulatory	ADJ
bionys-641	31	40	genes	gene	NOUN
bionys-641	31	41	(	(	PUNCT
bionys-641	31	42	d’arcy	d’arcy	PROPN
bionys-641	31	43	,	,	PUNCT
bionys-641	31	44	2019	2019	NUM
bionys-641	31	45	)	)	PUNCT
bionys-641	31	46	.	.	PUNCT
bionys-641	32	1	while	while	SCONJ
bionys-641	32	2	the	the	DET
bionys-641	32	3	cell	cell	NOUN
bionys-641	32	4	cycle	cycle	NOUN
bionys-641	32	5	and	and	CCONJ
bionys-641	32	6	cell	cell	NOUN
bionys-641	32	7	death	death	NOUN
bionys-641	32	8	require	require	VERB
bionys-641	32	9	a	a	DET
bionys-641	32	10	complicated	complicated	ADJ
bionys-641	32	11	interaction	interaction	NOUN
bionys-641	32	12	of	of	ADP
bionys-641	32	13	gene	gene	NOUN
bionys-641	32	14	products	product	NOUN
bionys-641	32	15	,	,	PUNCT
bionys-641	32	16	certain	certain	ADJ
bionys-641	32	17	receptors	receptor	NOUN
bionys-641	32	18	,	,	PUNCT
bionys-641	32	19	enzymes	enzyme	NOUN
bionys-641	32	20	,	,	PUNCT
bionys-641	32	21	and	and	CCONJ
bionys-641	32	22	regulatory	regulatory	ADJ
bionys-641	32	23	proteins	protein	NOUN
bionys-641	32	24	have	have	AUX
bionys-641	32	25	been	be	AUX
bionys-641	32	26	discovered	discover	VERB
bionys-641	32	27	to	to	PART
bionys-641	32	28	play	play	VERB
bionys-641	32	29	key	key	ADJ
bionys-641	32	30	roles	role	NOUN
bionys-641	32	31	in	in	ADP
bionys-641	32	32	those	those	DET
bionys-641	32	33	events	event	NOUN
bionys-641	32	34	.	.	PUNCT
bionys-641	33	1	mutations	mutation	NOUN
bionys-641	33	2	or	or	CCONJ
bionys-641	33	3	aberrant	aberrant	ADJ
bionys-641	33	4	expression	expression	NOUN
bionys-641	33	5	of	of	ADP
bionys-641	33	6	these	these	DET
bionys-641	33	7	regulatory	regulatory	ADJ
bionys-641	33	8	proteins	protein	NOUN
bionys-641	33	9	may	may	AUX
bionys-641	33	10	affect	affect	VERB
bionys-641	33	11	the	the	DET
bionys-641	33	12	normal	normal	ADJ
bionys-641	33	13	cell	cell	NOUN
bionys-641	33	14	cycle	cycle	NOUN
bionys-641	33	15	(	(	PUNCT
bionys-641	33	16	whitfield	whitfield	PROPN
bionys-641	33	17	et	et	PROPN
bionys-641	33	18	al	al	PROPN
bionys-641	33	19	.	.	PROPN
bionys-641	33	20	,	,	PUNCT
bionys-641	33	21	2002	2002	NUM
bionys-641	33	22	;	;	PUNCT
bionys-641	33	23	abreu	abreu	PROPN
bionys-641	33	24	velez	velez	PROPN
bionys-641	33	25	&	&	CCONJ
bionys-641	33	26	howard	howard	PROPN
bionys-641	33	27	,	,	PUNCT
bionys-641	33	28	2015	2015	NUM
bionys-641	33	29	)	)	PUNCT
bionys-641	33	30	.	.	PUNCT
bionys-641	34	1	for	for	ADP
bionys-641	34	2	example	example	NOUN
bionys-641	34	3	,	,	PUNCT
bionys-641	34	4	enzymes	enzyme	NOUN
bionys-641	34	5	of	of	ADP
bionys-641	34	6	the	the	DET
bionys-641	34	7	b	b	NOUN
bionys-641	34	8	-	-	PUNCT
bionys-641	34	9	cell	cell	NOUN
bionys-641	34	10	lymphoma-2	lymphoma-2	NUM
bionys-641	34	11	(	(	PUNCT
bionys-641	34	12	bcl2	bcl2	PROPN
bionys-641	34	13	)	)	PUNCT
bionys-641	34	14	family	family	NOUN
bionys-641	34	15	and	and	CCONJ
bionys-641	34	16	transglutaminase-2	transglutaminase-2	NUM
bionys-641	34	17	either	either	CCONJ
bionys-641	34	18	trigger	trigger	NOUN
bionys-641	34	19	or	or	CCONJ
bionys-641	34	20	inhibit	inhibit	VERB
bionys-641	34	21	apoptosis	apoptosis	NOUN
bionys-641	34	22	based	base	VERB
bionys-641	34	23	on	on	ADP
bionys-641	34	24	their	their	PRON
bionys-641	34	25	expression	expression	NOUN
bionys-641	34	26	(	(	PUNCT
bionys-641	34	27	upregulation	upregulation	NOUN
bionys-641	34	28	or	or	CCONJ
bionys-641	34	29	downregulation	downregulation	NOUN
bionys-641	34	30	)	)	PUNCT
bionys-641	34	31	,	,	PUNCT
bionys-641	34	32	localization	localization	NOUN
bionys-641	34	33	or	or	CCONJ
bionys-641	34	34	conformation	conformation	NOUN
bionys-641	34	35	(	(	PUNCT
bionys-641	34	36	budillon	budillon	NOUN
bionys-641	34	37	et	et	PROPN
bionys-641	34	38	al	al	PROPN
bionys-641	34	39	.	.	PROPN
bionys-641	34	40	,	,	PUNCT
bionys-641	34	41	2013	2013	NUM
bionys-641	34	42	;	;	PUNCT
bionys-641	34	43	murphy	murphy	PROPN
bionys-641	34	44	et	et	PROPN
bionys-641	34	45	al	al	PROPN
bionys-641	34	46	.	.	PROPN
bionys-641	34	47	,	,	PUNCT
bionys-641	34	48	2013	2013	NUM
bionys-641	34	49	)	)	PUNCT
bionys-641	34	50	.	.	PUNCT
bionys-641	35	1	regulated	regulated	ADJ
bionys-641	35	2	cell	cell	NOUN
bionys-641	35	3	death	death	NOUN
bionys-641	35	4	inhibition	inhibition	NOUN
bionys-641	35	5	may	may	AUX
bionys-641	35	6	directly	directly	ADV
bionys-641	35	7	affect	affect	VERB
bionys-641	35	8	cancer	cancer	NOUN
bionys-641	35	9	cells	cell	NOUN
bionys-641	35	10	'	'	PART
bionys-641	35	11	susceptibility	susceptibility	NOUN
bionys-641	35	12	to	to	ADP
bionys-641	35	13	chemotherapeutic	chemotherapeutic	ADJ
bionys-641	35	14	drugs	drug	NOUN
bionys-641	35	15	,	,	PUNCT
bionys-641	35	16	resulting	result	VERB
bionys-641	35	17	in	in	ADP
bionys-641	35	18	drug	drug	NOUN
bionys-641	35	19	resistance	resistance	NOUN
bionys-641	35	20	(	(	PUNCT
bionys-641	35	21	mansoori	mansoori	NOUN
bionys-641	35	22	et	et	PROPN
bionys-641	35	23	al	al	PROPN
bionys-641	35	24	.	.	PROPN
bionys-641	35	25	,	,	PUNCT
bionys-641	35	26	2017	2017	NUM
bionys-641	35	27	)	)	PUNCT
bionys-641	35	28	.	.	PUNCT
bionys-641	36	1	this	this	PRON
bionys-641	36	2	is	be	AUX
bionys-641	36	3	illustrated	illustrate	VERB
bionys-641	36	4	in	in	ADP
bionys-641	36	5	the	the	DET
bionys-641	36	6	case	case	NOUN
bionys-641	36	7	of	of	ADP
bionys-641	36	8	increased	increase	VERB
bionys-641	36	9	transglutaminase-2	transglutaminase-2	NUM
bionys-641	36	10	expression	expression	NOUN
bionys-641	36	11	,	,	PUNCT
bionys-641	36	12	which	which	PRON
bionys-641	36	13	is	be	AUX
bionys-641	36	14	associated	associate	VERB
bionys-641	36	15	with	with	ADP
bionys-641	36	16	poor	poor	ADJ
bionys-641	36	17	prognosis	prognosis	NOUN
bionys-641	36	18	and	and	CCONJ
bionys-641	36	19	relapse	relapse	NOUN
bionys-641	36	20	of	of	ADP
bionys-641	36	21	acute	acute	ADJ
bionys-641	36	22	myelocytic	myelocytic	ADJ
bionys-641	36	23	leukemia	leukemia	NOUN
bionys-641	36	24	(	(	PUNCT
bionys-641	36	25	aml	aml	PROPN
bionys-641	36	26	)	)	PUNCT
bionys-641	36	27	(	(	PUNCT
bionys-641	36	28	pierce	pierce	PROPN
bionys-641	36	29	et	et	PROPN
bionys-641	36	30	al	al	PROPN
bionys-641	36	31	.	.	PROPN
bionys-641	36	32	,	,	PUNCT
bionys-641	36	33	2013	2013	NUM
bionys-641	36	34	;	;	PUNCT
bionys-641	36	35	jacamo	jacamo	PROPN
bionys-641	36	36	et	et	PROPN
bionys-641	36	37	al	al	PROPN
bionys-641	36	38	.	.	PROPN
bionys-641	36	39	,	,	PUNCT
bionys-641	36	40	2016	2016	NUM
bionys-641	36	41	)	)	PUNCT
bionys-641	36	42	.	.	PUNCT
bionys-641	37	1	this	this	DET
bionys-641	37	2	review	review	NOUN
bionys-641	37	3	will	will	AUX
bionys-641	37	4	briefly	briefly	VERB
bionys-641	37	5	overview	overview	VERB
bionys-641	37	6	cell	cell	NOUN
bionys-641	37	7	death	death	NOUN
bionys-641	37	8	types	type	NOUN
bionys-641	37	9	and	and	CCONJ
bionys-641	37	10	their	their	PRON
bionys-641	37	11	associated	associated	ADJ
bionys-641	37	12	mechanisms	mechanism	NOUN
bionys-641	37	13	.	.	PUNCT
bionys-641	38	1	cell	cell	NOUN
bionys-641	38	2	death	death	NOUN
bionys-641	38	3	:	:	PUNCT
bionys-641	38	4	classification	classification	NOUN
bionys-641	38	5	and	and	CCONJ
bionys-641	38	6	explanation	explanation	VERB
bionys-641	38	7	the	the	DET
bionys-641	38	8	classification	classification	NOUN
bionys-641	38	9	of	of	ADP
bionys-641	38	10	cell	cell	NOUN
bionys-641	38	11	death	death	NOUN
bionys-641	38	12	was	be	AUX
bionys-641	38	13	initially	initially	ADV
bionys-641	38	14	based	base	VERB
bionys-641	38	15	on	on	ADP
bionys-641	38	16	the	the	DET
bionys-641	38	17	morphology	morphology	NOUN
bionys-641	38	18	and	and	CCONJ
bionys-641	38	19	structure	structure	NOUN
bionys-641	38	20	of	of	ADP
bionys-641	38	21	tissues	tissue	NOUN
bionys-641	38	22	and	and	CCONJ
bionys-641	38	23	cells	cell	NOUN
bionys-641	38	24	.	.	PUNCT
bionys-641	39	1	one	one	NUM
bionys-641	39	2	of	of	ADP
bionys-641	39	3	the	the	DET
bionys-641	39	4	earliest	early	ADJ
bionys-641	39	5	classifications	classification	NOUN
bionys-641	39	6	was	be	AUX
bionys-641	39	7	made	make	VERB
bionys-641	39	8	by	by	ADP
bionys-641	39	9	schweichel	schweichel	NOUN
bionys-641	39	10	and	and	CCONJ
bionys-641	39	11	merker	merker	NOUN
bionys-641	39	12	in	in	ADP
bionys-641	39	13	1973	1973	NUM
bionys-641	39	14	,	,	PUNCT
bionys-641	39	15	when	when	SCONJ
bionys-641	39	16	they	they	PRON
bionys-641	39	17	published	publish	VERB
bionys-641	39	18	a	a	DET
bionys-641	39	19	system	system	NOUN
bionys-641	39	20	based	base	VERB
bionys-641	39	21	on	on	ADP
bionys-641	39	22	morphology	morphology	NOUN
bionys-641	39	23	to	to	PART
bionys-641	39	24	classify	classify	VERB
bionys-641	39	25	three	three	NUM
bionys-641	39	26	types	type	NOUN
bionys-641	39	27	of	of	ADP
bionys-641	39	28	cell	cell	NOUN
bionys-641	39	29	death	death	NOUN
bionys-641	39	30	,	,	PUNCT
bionys-641	39	31	namely	namely	ADV
bionys-641	39	32	type	type	NOUN
bionys-641	39	33	i	i	PRON
bionys-641	39	34	,	,	PUNCT
bionys-641	39	35	type	type	NOUN
bionys-641	39	36	ii	ii	PROPN
bionys-641	39	37	,	,	PUNCT
bionys-641	39	38	and	and	CCONJ
bionys-641	39	39	type	type	NOUN
bionys-641	39	40	iii	iii	PROPN
bionys-641	39	41	(	(	PUNCT
bionys-641	39	42	schweichel	schweichel	PROPN
bionys-641	39	43	&	&	CCONJ
bionys-641	39	44	merker	merker	PROPN
bionys-641	39	45	,	,	PUNCT
bionys-641	39	46	1973	1973	NUM
bionys-641	39	47	)	)	PUNCT
bionys-641	39	48	.	.	PUNCT
bionys-641	40	1	type	type	NOUN
bionys-641	40	2	i	i	PRON
bionys-641	40	3	cell	cell	NOUN
bionys-641	40	4	death	death	NOUN
bionys-641	40	5	,	,	PUNCT
bionys-641	40	6	also	also	ADV
bionys-641	40	7	known	know	VERB
bionys-641	40	8	as	as	ADP
bionys-641	40	9	apoptosis	apoptosis	NOUN
bionys-641	40	10	,	,	PUNCT
bionys-641	40	11	is	be	AUX
bionys-641	40	12	defined	define	VERB
bionys-641	40	13	by	by	ADP
bionys-641	40	14	cellular	cellular	ADJ
bionys-641	40	15	shrinkage	shrinkage	NOUN
bionys-641	40	16	(	(	PUNCT
bionys-641	40	17	pyknosis	pyknosis	NOUN
bionys-641	40	18	)	)	PUNCT
bionys-641	40	19	,	,	PUNCT
bionys-641	40	20	membrane	membrane	NOUN
bionys-641	40	21	prominence	prominence	NOUN
bionys-641	40	22	(	(	PUNCT
bionys-641	40	23	blebbing	blebbe	VERB
bionys-641	40	24	)	)	PUNCT
bionys-641	40	25	,	,	PUNCT
bionys-641	40	26	apoptotic	apoptotic	ADJ
bionys-641	40	27	body	body	NOUN
bionys-641	40	28	emergence	emergence	NOUN
bionys-641	40	29	,	,	PUNCT
bionys-641	40	30	deoxyribonucleic	deoxyribonucleic	ADJ
bionys-641	40	31	acid	acid	NOUN
bionys-641	40	32	(	(	PUNCT
bionys-641	40	33	dna	dna	NOUN
bionys-641	40	34	)	)	PUNCT
bionys-641	40	35	disintegration	disintegration	NOUN
bionys-641	40	36	(	(	PUNCT
bionys-641	40	37	karyorrhexis	karyorrhexis	ADJ
bionys-641	40	38	)	)	PUNCT
bionys-641	40	39	,	,	PUNCT
bionys-641	40	40	and	and	CCONJ
bionys-641	40	41	chromatin	chromatin	NOUN
bionys-641	40	42	condensation	condensation	NOUN
bionys-641	40	43	(	(	PUNCT
bionys-641	40	44	portt	portt	NOUN
bionys-641	40	45	et	et	PROPN
bionys-641	40	46	al	al	PROPN
bionys-641	40	47	.	.	PROPN
bionys-641	40	48	,	,	PUNCT
bionys-641	40	49	2011	2011	NUM
bionys-641	40	50	)	)	PUNCT
bionys-641	40	51	.	.	PUNCT
bionys-641	41	1	this	this	DET
bionys-641	41	2	type	type	NOUN
bionys-641	41	3	of	of	ADP
bionys-641	41	4	cell	cell	NOUN
bionys-641	41	5	death	death	NOUN
bionys-641	41	6	is	be	AUX
bionys-641	41	7	additionally	additionally	ADV
bionys-641	41	8	recognized	recognize	VERB
bionys-641	41	9	as	as	ADP
bionys-641	41	10	shrinkage	shrinkage	NOUN
bionys-641	41	11	necrosis	necrosis	NOUN
bionys-641	41	12	,	,	PUNCT
bionys-641	41	13	considered	consider	VERB
bionys-641	41	14	a	a	DET
bionys-641	41	15	type	type	NOUN
bionys-641	41	16	of	of	ADP
bionys-641	41	17	non	non	ADJ
bionys-641	41	18	-	-	ADJ
bionys-641	41	19	pathologic	pathologic	ADJ
bionys-641	41	20	cell	cell	NOUN
bionys-641	41	21	death	death	NOUN
bionys-641	41	22	first	first	ADV
bionys-641	41	23	described	describe	VERB
bionys-641	41	24	by	by	ADP
bionys-641	41	25	a	a	DET
bionys-641	41	26	team	team	NOUN
bionys-641	41	27	of	of	ADP
bionys-641	41	28	investigators	investigator	NOUN
bionys-641	41	29	led	lead	VERB
bionys-641	41	30	by	by	ADP
bionys-641	41	31	john	john	PROPN
bionys-641	41	32	kerr	kerr	PROPN
bionys-641	41	33	(	(	PUNCT
bionys-641	41	34	1971	1971	NUM
bionys-641	41	35	)	)	PUNCT
bionys-641	41	36	.	.	PUNCT
bionys-641	42	1	next	next	ADV
bionys-641	42	2	,	,	PUNCT
bionys-641	42	3	type	type	NOUN
bionys-641	42	4	ii	ii	NOUN
bionys-641	42	5	cell	cell	NOUN
bionys-641	42	6	death	death	NOUN
bionys-641	42	7	is	be	AUX
bionys-641	42	8	defined	define	VERB
bionys-641	42	9	as	as	ADP
bionys-641	42	10	autophagy	autophagy	ADJ
bionys-641	42	11	-	-	PUNCT
bionys-641	42	12	dependent	dependent	ADJ
bionys-641	42	13	cell	cell	NOUN
bionys-641	42	14	death	death	NOUN
bionys-641	42	15	that	that	PRON
bionys-641	42	16	results	result	VERB
bionys-641	42	17	in	in	ADP
bionys-641	42	18	the	the	DET
bionys-641	42	19	formation	formation	NOUN
bionys-641	42	20	of	of	ADP
bionys-641	42	21	autophagic	autophagic	ADJ
bionys-641	42	22	vacuoles	vacuole	NOUN
bionys-641	42	23	consisting	consist	VERB
bionys-641	42	24	of	of	ADP
bionys-641	42	25	cytoplasmic	cytoplasmic	ADJ
bionys-641	42	26	substances	substance	NOUN
bionys-641	42	27	and	and	CCONJ
bionys-641	42	28	organelles	organelle	NOUN
bionys-641	42	29	to	to	PART
bionys-641	42	30	create	create	VERB
bionys-641	42	31	autophagic	autophagic	ADJ
bionys-641	42	32	bodies	body	NOUN
bionys-641	42	33	.	.	PUNCT
bionys-641	43	1	the	the	DET
bionys-641	43	2	process	process	NOUN
bionys-641	43	3	is	be	AUX
bionys-641	43	4	mediated	mediate	VERB
bionys-641	43	5	through	through	ADP
bionys-641	43	6	lysosomal	lysosomal	ADJ
bionys-641	43	7	involvement	involvement	NOUN
bionys-641	43	8	and	and	CCONJ
bionys-641	43	9	may	may	AUX
bionys-641	43	10	be	be	AUX
bionys-641	43	11	observed	observe	VERB
bionys-641	43	12	in	in	ADP
bionys-641	43	13	several	several	ADJ
bionys-641	43	14	cases	case	NOUN
bionys-641	43	15	,	,	PUNCT
bionys-641	43	16	broadly	broadly	ADV
bionys-641	43	17	classified	classify	VERB
bionys-641	43	18	as	as	ADP
bionys-641	43	19	microand	microand	NOUN
bionys-641	43	20	macroautophagy	macroautophagy	NOUN
bionys-641	43	21	(	(	PUNCT
bionys-641	43	22	todde	todde	X
bionys-641	43	23	et	et	PROPN
bionys-641	43	24	al	al	PROPN
bionys-641	43	25	.	.	PROPN
bionys-641	43	26	,	,	PUNCT
bionys-641	43	27	2009	2009	NUM
bionys-641	43	28	;	;	PUNCT
bionys-641	43	29	denton	denton	PROPN
bionys-641	43	30	&	&	CCONJ
bionys-641	43	31	kumar	kumar	PROPN
bionys-641	43	32	,	,	PUNCT
bionys-641	43	33	2019	2019	NUM
bionys-641	43	34	)	)	PUNCT
bionys-641	43	35	.	.	PUNCT
bionys-641	44	1	meanwhile	meanwhile	ADV
bionys-641	44	2	,	,	PUNCT
bionys-641	44	3	type	type	NOUN
bionys-641	44	4	iii	iii	NUM
bionys-641	44	5	cell	cell	NOUN
bionys-641	44	6	death	death	NOUN
bionys-641	44	7	,	,	PUNCT
bionys-641	44	8	frequently	frequently	ADV
bionys-641	44	9	designated	designate	VERB
bionys-641	44	10	as	as	ADP
bionys-641	44	11	necrosis	necrosis	NOUN
bionys-641	44	12	,	,	PUNCT
bionys-641	44	13	is	be	AUX
bionys-641	44	14	marked	mark	VERB
bionys-641	44	15	by	by	ADP
bionys-641	44	16	membrane	membrane	NOUN
bionys-641	44	17	damage	damage	NOUN
bionys-641	44	18	and	and	CCONJ
bionys-641	44	19	expansion	expansion	NOUN
bionys-641	44	20	of	of	ADP
bionys-641	44	21	subcellular	subcellular	ADJ
bionys-641	44	22	organelles	organelle	NOUN
bionys-641	44	23	.	.	PUNCT
bionys-641	45	1	necrosis	necrosis	NOUN
bionys-641	45	2	is	be	AUX
bionys-641	45	3	widely	widely	ADV
bionys-641	45	4	defined	define	VERB
bionys-641	45	5	as	as	ADP
bionys-641	45	6	uncontrollable	uncontrollable	ADJ
bionys-641	45	7	cell	cell	NOUN
bionys-641	45	8	death	death	NOUN
bionys-641	45	9	and	and	CCONJ
bionys-641	45	10	is	be	AUX
bionys-641	45	11	mainly	mainly	ADV
bionys-641	45	12	a	a	DET
bionys-641	45	13	pathological	pathological	ADJ
bionys-641	45	14	process	process	NOUN
bionys-641	45	15	(	(	PUNCT
bionys-641	45	16	tang	tang	NOUN
bionys-641	45	17	et	et	PROPN
bionys-641	45	18	al	al	PROPN
bionys-641	45	19	.	.	PROPN
bionys-641	45	20	,	,	PUNCT
bionys-641	45	21	2019	2019	NUM
bionys-641	45	22	)	)	PUNCT
bionys-641	45	23	.	.	PUNCT
bionys-641	46	1	for	for	ADP
bionys-641	46	2	several	several	ADJ
bionys-641	46	3	decades	decade	NOUN
bionys-641	46	4	,	,	PUNCT
bionys-641	46	5	apoptosis	apoptosis	NOUN
bionys-641	46	6	was	be	AUX
bionys-641	46	7	regarded	regard	VERB
bionys-641	46	8	as	as	ADP
bionys-641	46	9	the	the	DET
bionys-641	46	10	only	only	ADJ
bionys-641	46	11	plausible	plausible	ADJ
bionys-641	46	12	kind	kind	NOUN
bionys-641	46	13	of	of	ADP
bionys-641	46	14	programmed	program	VERB
bionys-641	46	15	cell	cell	NOUN
bionys-641	46	16	death	death	NOUN
bionys-641	46	17	(	(	PUNCT
bionys-641	46	18	suzanne	suzanne	PROPN
bionys-641	46	19	&	&	CCONJ
bionys-641	46	20	steller	steller	PROPN
bionys-641	46	21	,	,	PUNCT
bionys-641	46	22	2013	2013	NUM
bionys-641	46	23	)	)	PUNCT
bionys-641	46	24	.	.	PUNCT
bionys-641	47	1	necrosis	necrosis	NOUN
bionys-641	47	2	,	,	PUNCT
bionys-641	47	3	conversely	conversely	ADV
bionys-641	47	4	,	,	PUNCT
bionys-641	47	5	was	be	AUX
bionys-641	47	6	perceived	perceive	VERB
bionys-641	47	7	as	as	ADP
bionys-641	47	8	an	an	DET
bionys-641	47	9	unregulated	unregulated	ADJ
bionys-641	47	10	,	,	PUNCT
bionys-641	47	11	inadvertent	inadvertent	ADJ
bionys-641	47	12	consequence	consequence	NOUN
bionys-641	47	13	of	of	ADP
bionys-641	47	14	excessive	excessive	ADJ
bionys-641	47	15	physical	physical	ADJ
bionys-641	47	16	or	or	CCONJ
bionys-641	47	17	chemical	chemical	NOUN
bionys-641	47	18	injury	injury	NOUN
bionys-641	47	19	.	.	PUNCT
bionys-641	48	1	however	however	ADV
bionys-641	48	2	,	,	PUNCT
bionys-641	48	3	this	this	DET
bionys-641	48	4	dichotomy	dichotomy	NOUN
bionys-641	48	5	has	have	AUX
bionys-641	48	6	been	be	AUX
bionys-641	48	7	superseded	supersede	VERB
bionys-641	48	8	by	by	ADP
bionys-641	48	9	a	a	DET
bionys-641	48	10	more	more	ADV
bionys-641	48	11	nuanced	nuanced	ADJ
bionys-641	48	12	,	,	PUNCT
bionys-641	48	13	function	function	NOUN
bionys-641	48	14	-	-	PUNCT
bionys-641	48	15	oriented	orient	VERB
bionys-641	48	16	framework	framework	NOUN
bionys-641	48	17	determined	determine	VERB
bionys-641	48	18	by	by	ADP
bionys-641	48	19	the	the	DET
bionys-641	48	20	nomenclature	nomenclature	NOUN
bionys-641	48	21	committee	committee	NOUN
bionys-641	48	22	on	on	ADP
bionys-641	48	23	cell	cell	NOUN
bionys-641	48	24	death	death	NOUN
bionys-641	48	25	(	(	PUNCT
bionys-641	48	26	nccd	nccd	PROPN
bionys-641	48	27	)	)	PUNCT
bionys-641	48	28	(	(	PUNCT
bionys-641	48	29	galluzzi	galluzzi	NOUN
bionys-641	48	30	et	et	PROPN
bionys-641	48	31	al	al	PROPN
bionys-641	48	32	.	.	PROPN
bionys-641	48	33	,	,	PUNCT
bionys-641	48	34	2018	2018	NUM
bionys-641	48	35	)	)	PUNCT
bionys-641	48	36	.	.	PUNCT
bionys-641	49	1	currently	currently	ADV
bionys-641	49	2	,	,	PUNCT
bionys-641	49	3	cell	cell	NOUN
bionys-641	49	4	death	death	NOUN
bionys-641	49	5	has	have	AUX
bionys-641	49	6	been	be	AUX
bionys-641	49	7	classified	classify	VERB
bionys-641	49	8	as	as	ADP
bionys-641	49	9	either	either	DET
bionys-641	49	10	accidental	accidental	ADJ
bionys-641	49	11	cell	cell	NOUN
bionys-641	49	12	death	death	NOUN
bionys-641	49	13	(	(	PUNCT
bionys-641	49	14	acd	acd	NOUN
bionys-641	49	15	)	)	PUNCT
bionys-641	49	16	or	or	CCONJ
bionys-641	49	17	regulated	regulate	VERB
bionys-641	49	18	cell	cell	NOUN
bionys-641	49	19	death	death	NOUN
bionys-641	49	20	(	(	PUNCT
bionys-641	49	21	rcd	rcd	PROPN
bionys-641	49	22	)	)	PUNCT
bionys-641	49	23	,	,	PUNCT
bionys-641	49	24	depending	depend	VERB
bionys-641	49	25	on	on	ADP
bionys-641	49	26	functionality	functionality	NOUN
bionys-641	49	27	.	.	PUNCT
bionys-641	50	1	acd	acd	NOUN
bionys-641	50	2	is	be	AUX
bionys-641	50	3	prompted	prompt	VERB
bionys-641	50	4	by	by	ADP
bionys-641	50	5	a	a	DET
bionys-641	50	6	sudden	sudden	ADJ
bionys-641	50	7	assault	assault	NOUN
bionys-641	50	8	or	or	CCONJ
bionys-641	50	9	damage	damage	NOUN
bionys-641	50	10	that	that	PRON
bionys-641	50	11	disables	disable	VERB
bionys-641	50	12	all	all	DET
bionys-641	50	13	conceivable	conceivable	ADJ
bionys-641	50	14	control	control	NOUN
bionys-641	50	15	systems	system	NOUN
bionys-641	50	16	.	.	PUNCT
bionys-641	51	1	rcd	rcd	PROPN
bionys-641	51	2	,	,	PUNCT
bionys-641	51	3	on	on	ADP
bionys-641	51	4	the	the	DET
bionys-641	51	5	other	other	ADJ
bionys-641	51	6	hand	hand	NOUN
bionys-641	51	7	,	,	PUNCT
bionys-641	51	8	has	have	VERB
bionys-641	51	9	a	a	DET
bionys-641	51	10	distinct	distinct	ADJ
bionys-641	51	11	signaling	signal	VERB
bionys-641	51	12	cascade	cascade	NOUN
bionys-641	51	13	carried	carry	VERB
bionys-641	51	14	out	out	ADP
bionys-641	51	15	by	by	ADP
bionys-641	51	16	a	a	DET
bionys-641	51	17	specialized	specialized	ADJ
bionys-641	51	18	set	set	NOUN
bionys-641	51	19	of	of	ADP
bionys-641	51	20	effector	effector	NOUN
bionys-641	51	21	molecules	molecule	NOUN
bionys-641	51	22	,	,	PUNCT
bionys-641	51	23	as	as	ADV
bionys-641	51	24	well	well	ADV
bionys-641	51	25	as	as	ADP
bionys-641	51	26	distinctive	distinctive	ADJ
bionys-641	51	27	activities	activity	NOUN
bionys-641	51	28	,	,	PUNCT
bionys-641	51	29	molecular	molecular	ADJ
bionys-641	51	30	structures	structure	NOUN
bionys-641	51	31	,	,	PUNCT
bionys-641	51	32	and	and	CCONJ
bionys-641	51	33	immunological	immunological	ADJ
bionys-641	51	34	consequences	consequence	NOUN
bionys-641	51	35	.	.	PUNCT
bionys-641	52	1	it	it	PRON
bionys-641	52	2	can	can	AUX
bionys-641	52	3	also	also	ADV
bionys-641	52	4	be	be	AUX
bionys-641	52	5	pharmacologically	pharmacologically	ADV
bionys-641	52	6	or	or	CCONJ
bionys-641	52	7	genetically	genetically	ADV
bionys-641	52	8	modulated	modulate	VERB
bionys-641	52	9	(	(	PUNCT
bionys-641	52	10	galluzzi	galluzzi	NOUN
bionys-641	52	11	et	et	PROPN
bionys-641	52	12	al	al	PROPN
bionys-641	52	13	.	.	PROPN
bionys-641	52	14	,	,	PUNCT
bionys-641	52	15	2018	2018	NUM
bionys-641	52	16	;	;	PUNCT
bionys-641	52	17	van	van	PROPN
bionys-641	52	18	der	der	NOUN
bionys-641	52	19	meeren	meeren	NOUN
bionys-641	52	20	et	et	PROPN
bionys-641	52	21	al	al	PROPN
bionys-641	52	22	.	.	PROPN
bionys-641	52	23	,	,	PUNCT
bionys-641	52	24	2023	2023	NUM
bionys-641	52	25	)	)	PUNCT
bionys-641	52	26	.	.	PUNCT
bionys-641	53	1	rcd	rcd	PROPN
bionys-641	53	2	is	be	AUX
bionys-641	53	3	referred	refer	VERB
bionys-641	53	4	to	to	ADP
bionys-641	53	5	as	as	ADP
bionys-641	53	6	pcd	pcd	PROPN
bionys-641	53	7	when	when	SCONJ
bionys-641	53	8	it	it	PRON
bionys-641	53	9	develops	develop	VERB
bionys-641	53	10	under	under	ADP
bionys-641	53	11	physiological	physiological	ADJ
bionys-641	53	12	conditions	condition	NOUN
bionys-641	53	13	,	,	PUNCT
bionys-641	53	14	such	such	ADJ
bionys-641	53	15	as	as	ADP
bionys-641	53	16	during	during	ADP
bionys-641	53	17	embryonic	embryonic	ADJ
bionys-641	53	18	development	development	NOUN
bionys-641	53	19	(	(	PUNCT
bionys-641	53	20	díazmendoza	díazmendoza	PROPN
bionys-641	53	21	et	et	PROPN
bionys-641	53	22	al	al	PROPN
bionys-641	53	23	.	.	PROPN
bionys-641	53	24	,	,	PUNCT
bionys-641	53	25	2013	2013	NUM
bionys-641	53	26	;	;	PUNCT
bionys-641	53	27	tang	tang	X
bionys-641	53	28	et	et	PROPN
bionys-641	53	29	al	al	PROPN
bionys-641	53	30	.	.	PROPN
bionys-641	53	31	,	,	PUNCT
bionys-641	53	32	2019	2019	NUM
bionys-641	53	33	)	)	PUNCT
bionys-641	53	34	.	.	PUNCT
bionys-641	54	1	rcd	rcd	PROPN
bionys-641	54	2	can	can	AUX
bionys-641	54	3	be	be	AUX
bionys-641	54	4	divided	divide	VERB
bionys-641	54	5	into	into	ADP
bionys-641	54	6	at	at	ADV
bionys-641	54	7	least	least	ADJ
bionys-641	54	8	eleven	eleven	NUM
bionys-641	54	9	types	type	NOUN
bionys-641	54	10	depending	depend	VERB
bionys-641	54	11	on	on	ADP
bionys-641	54	12	its	its	PRON
bionys-641	54	13	molecular	molecular	ADJ
bionys-641	54	14	features	feature	NOUN
bionys-641	54	15	,	,	PUNCT
bionys-641	54	16	including	include	VERB
bionys-641	54	17	apoptosis	apoptosis	NOUN
bionys-641	54	18	,	,	PUNCT
bionys-641	54	19	necroptosis	necroptosis	NOUN
bionys-641	54	20	,	,	PUNCT
bionys-641	54	21	pyroptosis	pyroptosis	NOUN
bionys-641	54	22	,	,	PUNCT
bionys-641	54	23	ferroptosis	ferroptosis	NOUN
bionys-641	54	24	,	,	PUNCT
bionys-641	54	25	entotic	entotic	ADJ
bionys-641	54	26	cell	cell	NOUN
bionys-641	54	27	death	death	NOUN
bionys-641	54	28	,	,	PUNCT
bionys-641	54	29	netotic	netotic	ADJ
bionys-641	54	30	cell	cell	NOUN
bionys-641	54	31	death	death	NOUN
bionys-641	54	32	(	(	PUNCT
bionys-641	54	33	netosis	netosis	NOUN
bionys-641	54	34	)	)	PUNCT
bionys-641	54	35	,	,	PUNCT
bionys-641	54	36	parthanatos	parthanato	NOUN
bionys-641	54	37	,	,	PUNCT
bionys-641	54	38	lysosomedependent	lysosomedependent	NOUN
bionys-641	54	39	cell	cell	NOUN
bionys-641	54	40	death	death	NOUN
bionys-641	54	41	(	(	PUNCT
bionys-641	54	42	lcd	lcd	NOUN
bionys-641	54	43	)	)	PUNCT
bionys-641	54	44	,	,	PUNCT
bionys-641	54	45	autophagy	autophagy	VERB
bionys-641	54	46	-	-	PUNCT
bionys-641	54	47	dependent	dependent	ADJ
bionys-641	54	48	cell	cell	NOUN
bionys-641	54	49	death	death	NOUN
bionys-641	54	50	,	,	PUNCT
bionys-641	54	51	alkaliptosis	alkaliptosis	ADJ
bionys-641	54	52	,	,	PUNCT
bionys-641	54	53	and	and	CCONJ
bionys-641	54	54	oxeiptosis	oxeiptosis	NOUN
bionys-641	54	55	(	(	PUNCT
bionys-641	54	56	galluzzi	galluzzi	NOUN
bionys-641	54	57	et	et	PROPN
bionys-641	54	58	al	al	PROPN
bionys-641	54	59	.	.	PROPN
bionys-641	54	60	,	,	PUNCT
bionys-641	54	61	2018	2018	NUM
bionys-641	54	62	)	)	PUNCT
bionys-641	54	63	.	.	PUNCT
bionys-641	55	1	this	this	DET
bionys-641	55	2	paradigm	paradigm	NOUN
bionys-641	55	3	shift	shift	NOUN
bionys-641	55	4	was	be	AUX
bionys-641	55	5	prompted	prompt	VERB
bionys-641	55	6	by	by	ADP
bionys-641	55	7	the	the	DET
bionys-641	55	8	realization	realization	NOUN
bionys-641	55	9	that	that	SCONJ
bionys-641	55	10	necrosis	necrosis	NOUN
bionys-641	55	11	,	,	PUNCT
bionys-641	55	12	equivalent	equivalent	ADJ
bionys-641	55	13	to	to	ADP
bionys-641	55	14	apoptosis	apoptosis	VERB
bionys-641	55	15	,	,	PUNCT
bionys-641	55	16	can	can	AUX
bionys-641	55	17	occur	occur	VERB
bionys-641	55	18	in	in	ADP
bionys-641	55	19	a	a	DET
bionys-641	55	20	regulated	regulated	ADJ
bionys-641	55	21	fashion	fashion	NOUN
bionys-641	55	22	,	,	PUNCT
bionys-641	55	23	a	a	DET
bionys-641	55	24	phenomenon	phenomenon	NOUN
bionys-641	55	25	now	now	ADV
bionys-641	55	26	termed	term	VERB
bionys-641	55	27	necroptosis	necroptosis	NOUN
bionys-641	55	28	,	,	PUNCT
bionys-641	55	29	which	which	PRON
bionys-641	55	30	serves	serve	VERB
bionys-641	55	31	as	as	ADP
bionys-641	55	32	a	a	DET
bionys-641	55	33	host	host	NOUN
bionys-641	55	34	protective	protective	ADJ
bionys-641	55	35	mechanism	mechanism	NOUN
bionys-641	55	36	,	,	PUNCT
bionys-641	55	37	exhibiting	exhibit	VERB
bionys-641	55	38	antipathogenic	antipathogenic	ADJ
bionys-641	55	39	and	and	CCONJ
bionys-641	55	40	anticancer	anticancer	NOUN
bionys-641	55	41	properties	property	NOUN
bionys-641	55	42	(	(	PUNCT
bionys-641	55	43	khoury	khoury	PROPN
bionys-641	55	44	et	et	PROPN
bionys-641	55	45	al	al	PROPN
bionys-641	55	46	.	.	PROPN
bionys-641	55	47	,	,	PUNCT
bionys-641	55	48	2020	2020	NUM
bionys-641	55	49	;	;	PUNCT
bionys-641	55	50	ye	ye	PRON
bionys-641	55	51	et	et	NOUN
bionys-641	55	52	al	al	PROPN
bionys-641	55	53	.	.	PROPN
bionys-641	55	54	,	,	PUNCT
bionys-641	55	55	2023	2023	NUM
bionys-641	55	56	)	)	PUNCT
bionys-641	55	57	.	.	PUNCT
bionys-641	56	1	accidental	accidental	ADJ
bionys-641	56	2	cell	cell	NOUN
bionys-641	56	3	death	death	NOUN
bionys-641	56	4	:	:	PUNCT
bionys-641	56	5	necrosis	necrosis	NOUN
bionys-641	56	6	necrosis	necrosis	NOUN
bionys-641	56	7	(	(	PUNCT
bionys-641	56	8	fig	fig	NOUN
bionys-641	56	9	.	.	NOUN
bionys-641	56	10	1	1	NUM
bionys-641	56	11	)	)	PUNCT
bionys-641	56	12	,	,	PUNCT
bionys-641	56	13	unlike	unlike	ADP
bionys-641	56	14	apoptosis	apoptosis	NOUN
bionys-641	56	15	,	,	PUNCT
bionys-641	56	16	is	be	AUX
bionys-641	56	17	an	an	DET
bionys-641	56	18	unregulated	unregulated	ADJ
bionys-641	56	19	type	type	NOUN
bionys-641	56	20	of	of	ADP
bionys-641	56	21	cell	cell	NOUN
bionys-641	56	22	death	death	NOUN
bionys-641	56	23	that	that	PRON
bionys-641	56	24	occurs	occur	VERB
bionys-641	56	25	due	due	ADJ
bionys-641	56	26	to	to	ADP
bionys-641	56	27	sudden	sudden	ADJ
bionys-641	56	28	external	external	ADJ
bionys-641	56	29	insults	insult	NOUN
bionys-641	56	30	such	such	ADJ
bionys-641	56	31	as	as	ADP
bionys-641	56	32	hypoxia	hypoxia	NOUN
bionys-641	56	33	,	,	PUNCT
bionys-641	56	34	radiation	radiation	NOUN
bionys-641	56	35	,	,	PUNCT
bionys-641	56	36	extreme	extreme	ADJ
bionys-641	56	37	heat	heat	NOUN
bionys-641	56	38	,	,	PUNCT
bionys-641	56	39	and	and	CCONJ
bionys-641	56	40	toxins	toxin	NOUN
bionys-641	56	41	that	that	PRON
bionys-641	56	42	cause	cause	VERB
bionys-641	56	43	severe	severe	ADJ
bionys-641	56	44	damage	damage	NOUN
bionys-641	56	45	and	and	CCONJ
bionys-641	56	46	render	render	VERB
bionys-641	56	47	cells	cell	NOUN
bionys-641	56	48	unable	unable	ADJ
bionys-641	56	49	to	to	PART
bionys-641	56	50	function	function	VERB
bionys-641	56	51	properly	properly	ADV
bionys-641	56	52	.	.	PUNCT
bionys-641	57	1	this	this	DET
bionys-641	57	2	process	process	NOUN
bionys-641	57	3	frequently	frequently	ADV
bionys-641	57	4	entails	entail	VERB
bionys-641	57	5	a	a	DET
bionys-641	57	6	surge	surge	NOUN
bionys-641	57	7	in	in	ADP
bionys-641	57	8	the	the	DET
bionys-641	57	9	expression	expression	NOUN
bionys-641	57	10	of	of	ADP
bionys-641	57	11	diverse	diverse	ADJ
bionys-641	57	12	proinflammatory	proinflammatory	ADJ
bionys-641	57	13	factors	factor	NOUN
bionys-641	57	14	,	,	PUNCT
bionys-641	57	15	such	such	ADJ
bionys-641	57	16	as	as	ADP
bionys-641	57	17	nuclear	nuclear	ADJ
bionys-641	57	18	factor	factor	NOUN
bionys-641	57	19	-	-	PUNCT
bionys-641	57	20	κb	κb	PROPN
bionys-641	57	21	(	(	PUNCT
bionys-641	57	22	li	li	PROPN
bionys-641	57	23	et	et	PROPN
bionys-641	57	24	al	al	PROPN
bionys-641	57	25	.	.	PROPN
bionys-641	57	26	,	,	PUNCT
bionys-641	57	27	2001	2001	NUM
bionys-641	57	28	)	)	PUNCT
bionys-641	57	29	.	.	PUNCT
bionys-641	58	1	these	these	DET
bionys-641	58	2	scenarios	scenario	NOUN
bionys-641	58	3	result	result	VERB
bionys-641	58	4	in	in	ADP
bionys-641	58	5	cell	cell	NOUN
bionys-641	58	6	swelling	swell	VERB
bionys-641	58	7	(	(	PUNCT
bionys-641	58	8	oncosis	oncosis	NOUN
bionys-641	58	9	)	)	PUNCT
bionys-641	58	10	followed	follow	VERB
bionys-641	58	11	by	by	ADP
bionys-641	58	12	rupture	rupture	NOUN
bionys-641	58	13	of	of	ADP
bionys-641	58	14	the	the	DET
bionys-641	58	15	cell	cell	NOUN
bionys-641	58	16	membrane	membrane	NOUN
bionys-641	58	17	,	,	PUNCT
bionys-641	58	18	leading	lead	VERB
bionys-641	58	19	to	to	ADP
bionys-641	58	20	a	a	DET
bionys-641	58	21	release	release	NOUN
bionys-641	58	22	of	of	ADP
bionys-641	58	23	cell	cell	NOUN
bionys-641	58	24	contents	content	NOUN
bionys-641	58	25	to	to	ADP
bionys-641	58	26	the	the	DET
bionys-641	58	27	surrounding	surround	VERB
bionys-641	58	28	region	region	NOUN
bionys-641	58	29	,	,	PUNCT
bionys-641	58	30	which	which	PRON
bionys-641	58	31	triggers	trigger	VERB
bionys-641	58	32	an	an	DET
bionys-641	58	33	inflammatory	inflammatory	ADJ
bionys-641	58	34	biologica	biologica	NOUN
bionys-641	58	35	nyssana	nyssana	PROPN
bionys-641	59	1	●	●	PUNCT
bionys-641	59	2	16	16	NUM
bionys-641	59	3	(	(	PUNCT
bionys-641	59	4	2	2	NUM
bionys-641	59	5	)	)	PUNCT
bionys-641	59	6	december	december	PROPN
bionys-641	59	7	2025	2025	NUM
bionys-641	59	8	:	:	PUNCT
bionys-641	59	9	liana	liana	NOUN
bionys-641	59	10	et	et	PROPN
bionys-641	59	11	al	al	PROPN
bionys-641	59	12	.	.	PUNCT
bionys-641	60	1	●	●	PUNCT
bionys-641	60	2	cell	cell	NOUN
bionys-641	60	3	deaths	death	NOUN
bionys-641	60	4	and	and	CCONJ
bionys-641	60	5	their	their	PRON
bionys-641	60	6	associated	associate	VERB
bionys-641	60	7	mechanisms	mechanism	NOUN
bionys-641	60	8	biologica	biologica	PROPN
bionys-641	60	9	nyssana	nyssana	PROPN
bionys-641	60	10	●	●	PUNCT
bionys-641	60	11	16	16	NUM
bionys-641	60	12	(	(	PUNCT
bionys-641	60	13	2	2	NUM
bionys-641	60	14	)	)	PUNCT
bionys-641	60	15	december	december	PROPN
bionys-641	60	16	2025	2025	NUM
bionys-641	60	17	:	:	PUNCT
bionys-641	60	18	liana	liana	NOUN
bionys-641	60	19	et	et	PROPN
bionys-641	60	20	al	al	PROPN
bionys-641	60	21	.	.	PUNCT
bionys-641	61	1	●	●	PUNCT
bionys-641	61	2	cell	cell	NOUN
bionys-641	61	3	deaths	death	NOUN
bionys-641	61	4	and	and	CCONJ
bionys-641	61	5	their	their	PRON
bionys-641	61	6	associated	associate	VERB
bionys-641	61	7	mechanisms	mechanism	NOUN
bionys-641	61	8	fig	fig	NOUN
bionys-641	61	9	.	.	PUNCT
bionys-641	62	1	1	1	X
bionys-641	62	2	.	.	X
bionys-641	62	3	necrosis	necrosis	NOUN
bionys-641	62	4	process	process	NOUN
bionys-641	62	5	chain	chain	NOUN
bionys-641	62	6	reaction	reaction	NOUN
bionys-641	62	7	and	and	CCONJ
bionys-641	62	8	leads	lead	VERB
bionys-641	62	9	to	to	ADP
bionys-641	62	10	tissue	tissue	NOUN
bionys-641	62	11	breakdown	breakdown	NOUN
bionys-641	62	12	(	(	PUNCT
bionys-641	62	13	helgoe	helgoe	NOUN
bionys-641	62	14	et	et	NOUN
bionys-641	62	15	al	al	PROPN
bionys-641	62	16	.	.	PROPN
bionys-641	62	17	,	,	PUNCT
bionys-641	62	18	2024	2024	NUM
bionys-641	62	19	)	)	PUNCT
bionys-641	62	20	.	.	PUNCT
bionys-641	63	1	overall	overall	ADV
bionys-641	63	2	,	,	PUNCT
bionys-641	63	3	the	the	DET
bionys-641	63	4	necrosis	necrosis	NOUN
bionys-641	63	5	process	process	NOUN
bionys-641	63	6	does	do	AUX
bionys-641	63	7	not	not	PART
bionys-641	63	8	require	require	VERB
bionys-641	63	9	energy	energy	NOUN
bionys-641	63	10	.	.	PUNCT
bionys-641	64	1	the	the	DET
bionys-641	64	2	notion	notion	NOUN
bionys-641	64	3	of	of	ADP
bionys-641	64	4	necrosis	necrosis	NOUN
bionys-641	64	5	as	as	ADP
bionys-641	64	6	a	a	DET
bionys-641	64	7	contrast	contrast	NOUN
bionys-641	64	8	to	to	ADP
bionys-641	64	9	apoptosis	apoptosis	NOUN
bionys-641	64	10	is	be	AUX
bionys-641	64	11	valuable	valuable	ADJ
bionys-641	64	12	.	.	PUNCT
bionys-641	65	1	however	however	ADV
bionys-641	65	2	,	,	PUNCT
bionys-641	65	3	in	in	ADP
bionys-641	65	4	cell	cell	NOUN
bionys-641	65	5	culture	culture	NOUN
bionys-641	65	6	,	,	PUNCT
bionys-641	65	7	what	what	PRON
bionys-641	65	8	is	be	AUX
bionys-641	65	9	frequently	frequently	ADV
bionys-641	65	10	referred	refer	VERB
bionys-641	65	11	to	to	ADP
bionys-641	65	12	as	as	SCONJ
bionys-641	65	13	the	the	DET
bionys-641	65	14	necrosis	necrosis	NOUN
bionys-641	65	15	process	process	NOUN
bionys-641	65	16	is	be	AUX
bionys-641	65	17	basically	basically	ADV
bionys-641	65	18	the	the	DET
bionys-641	65	19	remains	remain	NOUN
bionys-641	65	20	of	of	ADP
bionys-641	65	21	cells	cell	NOUN
bionys-641	65	22	in	in	ADP
bionys-641	65	23	the	the	DET
bionys-641	65	24	late	late	ADJ
bionys-641	65	25	-	-	PUNCT
bionys-641	65	26	stage	stage	NOUN
bionys-641	65	27	apoptotic	apoptotic	ADJ
bionys-641	65	28	events	event	NOUN
bionys-641	65	29	,	,	PUNCT
bionys-641	65	30	where	where	SCONJ
bionys-641	65	31	there	there	PRON
bionys-641	65	32	is	be	VERB
bionys-641	65	33	a	a	DET
bionys-641	65	34	compromised	compromised	ADJ
bionys-641	65	35	structural	structural	ADJ
bionys-641	65	36	integrity	integrity	NOUN
bionys-641	65	37	of	of	ADP
bionys-641	65	38	apoptotic	apoptotic	ADJ
bionys-641	65	39	bodies	body	NOUN
bionys-641	65	40	.	.	PUNCT
bionys-641	66	1	this	this	PRON
bionys-641	66	2	typically	typically	ADV
bionys-641	66	3	appears	appear	VERB
bionys-641	66	4	as	as	ADP
bionys-641	66	5	the	the	DET
bionys-641	66	6	presence	presence	NOUN
bionys-641	66	7	of	of	ADP
bionys-641	66	8	cellular	cellular	ADJ
bionys-641	66	9	chunks	chunk	NOUN
bionys-641	66	10	in	in	ADP
bionys-641	66	11	the	the	DET
bionys-641	66	12	media	medium	NOUN
bionys-641	66	13	,	,	PUNCT
bionys-641	66	14	which	which	PRON
bionys-641	66	15	is	be	AUX
bionys-641	66	16	mistakenly	mistakenly	ADV
bionys-641	66	17	attributed	attribute	VERB
bionys-641	66	18	to	to	ADP
bionys-641	66	19	necrosis	necrosis	NOUN
bionys-641	66	20	(	(	PUNCT
bionys-641	66	21	berghe	berghe	NOUN
bionys-641	66	22	et	et	NOUN
bionys-641	66	23	al	al	PROPN
bionys-641	66	24	.	.	PROPN
bionys-641	66	25	,	,	PUNCT
bionys-641	66	26	2010	2010	NUM
bionys-641	66	27	)	)	PUNCT
bionys-641	66	28	.	.	PUNCT
bionys-641	67	1	within	within	ADP
bionys-641	67	2	a	a	DET
bionys-641	67	3	living	live	VERB
bionys-641	67	4	organism	organism	NOUN
bionys-641	67	5	,	,	PUNCT
bionys-641	67	6	phagocytosis	phagocytosis	NOUN
bionys-641	67	7	typically	typically	ADV
bionys-641	67	8	occurs	occur	VERB
bionys-641	67	9	,	,	PUNCT
bionys-641	67	10	where	where	SCONJ
bionys-641	67	11	circulating	circulate	VERB
bionys-641	67	12	white	white	ADJ
bionys-641	67	13	blood	blood	NOUN
bionys-641	67	14	cells	cell	NOUN
bionys-641	67	15	devour	devour	VERB
bionys-641	67	16	and	and	CCONJ
bionys-641	67	17	remove	remove	VERB
bionys-641	67	18	these	these	DET
bionys-641	67	19	apoptotic	apoptotic	ADJ
bionys-641	67	20	bodies	body	NOUN
bionys-641	67	21	.	.	PUNCT
bionys-641	68	1	however	however	ADV
bionys-641	68	2	,	,	PUNCT
bionys-641	68	3	in	in	ADP
bionys-641	68	4	a	a	DET
bionys-641	68	5	monoculture	monoculture	NOUN
bionys-641	68	6	,	,	PUNCT
bionys-641	68	7	this	this	DET
bionys-641	68	8	phagocytosis	phagocytosis	NOUN
bionys-641	68	9	process	process	NOUN
bionys-641	68	10	does	do	AUX
bionys-641	68	11	not	not	PART
bionys-641	68	12	occur	occur	VERB
bionys-641	68	13	(	(	PUNCT
bionys-641	68	14	liang	liang	PROPN
bionys-641	68	15	et	et	PROPN
bionys-641	68	16	al	al	PROPN
bionys-641	68	17	.	.	PROPN
bionys-641	68	18	,	,	PUNCT
bionys-641	68	19	2014	2014	NUM
bionys-641	68	20	)	)	PUNCT
bionys-641	68	21	.	.	PUNCT
bionys-641	69	1	this	this	PRON
bionys-641	69	2	can	can	AUX
bionys-641	69	3	complicate	complicate	VERB
bionys-641	69	4	identifying	identify	VERB
bionys-641	69	5	the	the	DET
bionys-641	69	6	precise	precise	ADJ
bionys-641	69	7	process	process	NOUN
bionys-641	69	8	by	by	ADP
bionys-641	69	9	which	which	PRON
bionys-641	69	10	cell	cell	NOUN
bionys-641	69	11	death	death	NOUN
bionys-641	69	12	occurs	occur	VERB
bionys-641	69	13	.	.	PUNCT
bionys-641	70	1	regulated	regulated	ADJ
bionys-641	70	2	cell	cell	NOUN
bionys-641	70	3	death	death	NOUN
bionys-641	70	4	apoptosis	apoptosis	NOUN
bionys-641	70	5	apoptosis	apoptosis	NOUN
bionys-641	70	6	(	(	PUNCT
bionys-641	70	7	fig	fig	NOUN
bionys-641	70	8	.	.	NOUN
bionys-641	70	9	2	2	NUM
bionys-641	70	10	)	)	PUNCT
bionys-641	70	11	is	be	AUX
bionys-641	70	12	considered	consider	VERB
bionys-641	70	13	the	the	DET
bionys-641	70	14	archetypal	archetypal	ADJ
bionys-641	70	15	form	form	NOUN
bionys-641	70	16	of	of	ADP
bionys-641	70	17	rcd	rcd	PROPN
bionys-641	70	18	,	,	PUNCT
bionys-641	70	19	a	a	DET
bionys-641	70	20	meticulously	meticulously	ADV
bionys-641	70	21	orchestrated	orchestrate	VERB
bionys-641	70	22	process	process	NOUN
bionys-641	70	23	of	of	ADP
bionys-641	70	24	cellular	cellular	ADJ
bionys-641	70	25	self	self	NOUN
bionys-641	70	26	-	-	PUNCT
bionys-641	70	27	dismantling	dismantle	VERB
bionys-641	70	28	directed	direct	VERB
bionys-641	70	29	by	by	ADP
bionys-641	70	30	a	a	DET
bionys-641	70	31	family	family	NOUN
bionys-641	70	32	of	of	ADP
bionys-641	70	33	cysteine	cysteine	ADJ
bionys-641	70	34	-	-	PUNCT
bionys-641	70	35	aspartic	aspartic	ADJ
bionys-641	70	36	proteases	protease	NOUN
bionys-641	70	37	known	know	VERB
bionys-641	70	38	as	as	ADP
bionys-641	70	39	caspases	caspase	NOUN
bionys-641	70	40	(	(	PUNCT
bionys-641	70	41	brentnall	brentnall	NOUN
bionys-641	70	42	et	et	PROPN
bionys-641	70	43	al	al	PROPN
bionys-641	70	44	.	.	PROPN
bionys-641	70	45	,	,	PUNCT
bionys-641	70	46	2013	2013	NUM
bionys-641	70	47	)	)	PUNCT
bionys-641	70	48	.	.	PUNCT
bionys-641	71	1	caspases	caspase	NOUN
bionys-641	71	2	may	may	AUX
bionys-641	71	3	be	be	AUX
bionys-641	71	4	classified	classify	VERB
bionys-641	71	5	into	into	ADP
bionys-641	71	6	two	two	NUM
bionys-641	71	7	groups	group	NOUN
bionys-641	71	8	:	:	PUNCT
bionys-641	71	9	initiator	initiator	NOUN
bionys-641	71	10	and	and	CCONJ
bionys-641	71	11	executor	executor	NOUN
bionys-641	71	12	caspases	caspase	NOUN
bionys-641	71	13	.	.	PUNCT
bionys-641	72	1	initiator	initiator	NOUN
bionys-641	72	2	caspases	caspase	NOUN
bionys-641	72	3	(	(	PUNCT
bionys-641	72	4	caspases	caspase	NOUN
bionys-641	72	5	8	8	NUM
bionys-641	72	6	and	and	CCONJ
bionys-641	72	7	9	9	NUM
bionys-641	72	8	)	)	PUNCT
bionys-641	72	9	are	be	AUX
bionys-641	72	10	activated	activate	VERB
bionys-641	72	11	from	from	ADP
bionys-641	72	12	dormant	dormant	ADJ
bionys-641	72	13	procaspase	procaspase	NOUN
bionys-641	72	14	forms	form	NOUN
bionys-641	72	15	upon	upon	SCONJ
bionys-641	72	16	detection	detection	NOUN
bionys-641	72	17	of	of	ADP
bionys-641	72	18	cell	cell	NOUN
bionys-641	72	19	injury	injury	NOUN
bionys-641	72	20	,	,	PUNCT
bionys-641	72	21	and	and	CCONJ
bionys-641	72	22	they	they	PRON
bionys-641	72	23	subsequently	subsequently	ADV
bionys-641	72	24	trigger	trigger	VERB
bionys-641	72	25	executor	executor	NOUN
bionys-641	72	26	caspases	caspase	NOUN
bionys-641	72	27	(	(	PUNCT
bionys-641	72	28	caspases	caspases	PROPN
bionys-641	72	29	3	3	NUM
bionys-641	72	30	,	,	PUNCT
bionys-641	72	31	6	6	NUM
bionys-641	72	32	,	,	PUNCT
bionys-641	72	33	and	and	CCONJ
bionys-641	72	34	7	7	X
bionys-641	72	35	)	)	PUNCT
bionys-641	72	36	(	(	PUNCT
bionys-641	72	37	aral	aral	PROPN
bionys-641	72	38	et	et	PROPN
bionys-641	72	39	al	al	PROPN
bionys-641	72	40	.	.	PROPN
bionys-641	72	41	,	,	PUNCT
bionys-641	72	42	2019	2019	NUM
bionys-641	72	43	)	)	PUNCT
bionys-641	72	44	.	.	PUNCT
bionys-641	73	1	these	these	DET
bionys-641	73	2	enzymes	enzyme	NOUN
bionys-641	73	3	initiate	initiate	VERB
bionys-641	73	4	a	a	DET
bionys-641	73	5	series	series	NOUN
bionys-641	73	6	of	of	ADP
bionys-641	73	7	processes	process	NOUN
bionys-641	73	8	that	that	PRON
bionys-641	73	9	lead	lead	VERB
bionys-641	73	10	to	to	ADP
bionys-641	73	11	dna	dna	PROPN
bionys-641	73	12	fragmentation	fragmentation	NOUN
bionys-641	73	13	via	via	ADP
bionys-641	73	14	endonuclease	endonuclease	NOUN
bionys-641	73	15	activation	activation	NOUN
bionys-641	73	16	,	,	PUNCT
bionys-641	73	17	nuclear	nuclear	ADJ
bionys-641	73	18	protein	protein	NOUN
bionys-641	73	19	disintegration	disintegration	NOUN
bionys-641	73	20	,	,	PUNCT
bionys-641	73	21	cytoskeleton	cytoskeleton	NOUN
bionys-641	73	22	disruption	disruption	NOUN
bionys-641	73	23	,	,	PUNCT
bionys-641	73	24	protein	protein	NOUN
bionys-641	73	25	crosslinking	crosslinking	NOUN
bionys-641	73	26	,	,	PUNCT
bionys-641	73	27	production	production	NOUN
bionys-641	73	28	of	of	ADP
bionys-641	73	29	ligands	ligand	NOUN
bionys-641	73	30	for	for	ADP
bionys-641	73	31	phagocytic	phagocytic	ADJ
bionys-641	73	32	cells	cell	NOUN
bionys-641	73	33	,	,	PUNCT
bionys-641	73	34	and	and	CCONJ
bionys-641	73	35	apoptotic	apoptotic	ADJ
bionys-641	73	36	body	body	NOUN
bionys-641	73	37	formation	formation	NOUN
bionys-641	73	38	.	.	PUNCT
bionys-641	74	1	an	an	DET
bionys-641	74	2	important	important	ADJ
bionys-641	74	3	feature	feature	NOUN
bionys-641	74	4	to	to	PART
bionys-641	74	5	note	note	VERB
bionys-641	74	6	is	be	AUX
bionys-641	74	7	that	that	SCONJ
bionys-641	74	8	the	the	DET
bionys-641	74	9	cell	cell	NOUN
bionys-641	74	10	membrane	membrane	NOUN
bionys-641	74	11	remains	remain	VERB
bionys-641	74	12	intact	intact	ADJ
bionys-641	74	13	as	as	SCONJ
bionys-641	74	14	the	the	DET
bionys-641	74	15	cell	cell	NOUN
bionys-641	74	16	is	be	AUX
bionys-641	74	17	packaged	package	VERB
bionys-641	74	18	into	into	ADP
bionys-641	74	19	smaller	small	ADJ
bionys-641	74	20	,	,	PUNCT
bionys-641	74	21	membrane	membrane	NOUN
bionys-641	74	22	-	-	PUNCT
bionys-641	74	23	bound	bind	VERB
bionys-641	74	24	vesicles	vesicle	NOUN
bionys-641	74	25	called	call	VERB
bionys-641	74	26	apoptotic	apoptotic	ADJ
bionys-641	74	27	bodies	body	NOUN
bionys-641	74	28	during	during	ADP
bionys-641	74	29	the	the	DET
bionys-641	74	30	process	process	NOUN
bionys-641	74	31	(	(	PUNCT
bionys-641	74	32	zhao	zhao	PROPN
bionys-641	74	33	et	et	PROPN
bionys-641	74	34	al	al	PROPN
bionys-641	74	35	.	.	PROPN
bionys-641	74	36	,	,	PUNCT
bionys-641	74	37	2021	2021	NUM
bionys-641	74	38	)	)	PUNCT
bionys-641	74	39	.	.	PUNCT
bionys-641	75	1	macrophages	macrophage	NOUN
bionys-641	75	2	then	then	ADV
bionys-641	75	3	swiftly	swiftly	ADV
bionys-641	75	4	phagocytose	phagocytose	VERB
bionys-641	75	5	the	the	DET
bionys-641	75	6	apoptotic	apoptotic	ADJ
bionys-641	75	7	bodies	body	NOUN
bionys-641	75	8	that	that	PRON
bionys-641	75	9	have	have	AUX
bionys-641	75	10	formed	form	VERB
bionys-641	75	11	,	,	PUNCT
bionys-641	75	12	leading	lead	VERB
bionys-641	75	13	to	to	ADP
bionys-641	75	14	the	the	DET
bionys-641	75	15	non	non	ADJ
bionys-641	75	16	-	-	ADJ
bionys-641	75	17	inflammatory	inflammatory	ADJ
bionys-641	75	18	removal	removal	NOUN
bionys-641	75	19	of	of	ADP
bionys-641	75	20	malignant	malignant	ADJ
bionys-641	75	21	and	and	CCONJ
bionys-641	75	22	precancerous	precancerous	ADJ
bionys-641	75	23	cells	cell	NOUN
bionys-641	75	24	and	and	CCONJ
bionys-641	75	25	a	a	DET
bionys-641	75	26	decrease	decrease	NOUN
bionys-641	75	27	in	in	ADP
bionys-641	75	28	tissue	tissue	NOUN
bionys-641	75	29	damage	damage	NOUN
bionys-641	75	30	from	from	ADP
bionys-641	75	31	erroneous	erroneous	ADJ
bionys-641	75	32	immune	immune	ADJ
bionys-641	75	33	reactions	reaction	NOUN
bionys-641	75	34	(	(	PUNCT
bionys-641	75	35	hirayama	hirayama	PROPN
bionys-641	75	36	et	et	PROPN
bionys-641	75	37	al	al	PROPN
bionys-641	75	38	.	.	PROPN
bionys-641	75	39	,	,	PUNCT
bionys-641	75	40	2017	2017	NUM
bionys-641	75	41	)	)	PUNCT
bionys-641	75	42	.	.	PUNCT
bionys-641	76	1	apoptosis	apoptosis	NOUN
bionys-641	76	2	is	be	AUX
bionys-641	76	3	estimated	estimate	VERB
bionys-641	76	4	to	to	PART
bionys-641	76	5	occur	occur	VERB
bionys-641	76	6	at	at	ADP
bionys-641	76	7	a	a	DET
bionys-641	76	8	rate	rate	NOUN
bionys-641	76	9	of	of	ADP
bionys-641	76	10	1×109	1×109	NUM
bionys-641	76	11	cells	cell	NOUN
bionys-641	76	12	daily	daily	ADV
bionys-641	76	13	in	in	ADP
bionys-641	76	14	the	the	DET
bionys-641	76	15	human	human	ADJ
bionys-641	76	16	body	body	NOUN
bionys-641	76	17	(	(	PUNCT
bionys-641	76	18	elliott	elliott	PROPN
bionys-641	76	19	&	&	CCONJ
bionys-641	76	20	ravichandran	ravichandran	PROPN
bionys-641	76	21	,	,	PUNCT
bionys-641	76	22	2010	2010	NUM
bionys-641	76	23	)	)	PUNCT
bionys-641	76	24	.	.	PUNCT
bionys-641	77	1	this	this	DET
bionys-641	77	2	process	process	NOUN
bionys-641	77	3	is	be	AUX
bionys-641	77	4	characterized	characterize	VERB
bionys-641	77	5	by	by	ADP
bionys-641	77	6	an	an	DET
bionys-641	77	7	interruption	interruption	NOUN
bionys-641	77	8	of	of	ADP
bionys-641	77	9	cell	cell	NOUN
bionys-641	77	10	division	division	NOUN
bionys-641	77	11	and	and	CCONJ
bionys-641	77	12	expansion	expansion	NOUN
bionys-641	77	13	,	,	PUNCT
bionys-641	77	14	followed	follow	VERB
bionys-641	77	15	by	by	ADP
bionys-641	77	16	a	a	DET
bionys-641	77	17	sequence	sequence	NOUN
bionys-641	77	18	of	of	ADP
bionys-641	77	19	steps	step	NOUN
bionys-641	77	20	to	to	PART
bionys-641	77	21	prepare	prepare	VERB
bionys-641	77	22	the	the	DET
bionys-641	77	23	cell	cell	NOUN
bionys-641	77	24	for	for	ADP
bionys-641	77	25	controlled	control	VERB
bionys-641	77	26	death	death	NOUN
bionys-641	77	27	so	so	SCONJ
bionys-641	77	28	that	that	SCONJ
bionys-641	77	29	its	its	PRON
bionys-641	77	30	materials	material	NOUN
bionys-641	77	31	do	do	AUX
bionys-641	77	32	not	not	PART
bionys-641	77	33	leak	leak	VERB
bionys-641	77	34	into	into	ADP
bionys-641	77	35	the	the	DET
bionys-641	77	36	vicinity	vicinity	NOUN
bionys-641	77	37	(	(	PUNCT
bionys-641	77	38	d’arcy	d’arcy	PROPN
bionys-641	77	39	,	,	PUNCT
bionys-641	77	40	2019	2019	NUM
bionys-641	77	41	)	)	PUNCT
bionys-641	77	42	.	.	PUNCT
bionys-641	78	1	apoptosis	apoptosis	NOUN
bionys-641	78	2	may	may	AUX
bionys-641	78	3	occur	occur	VERB
bionys-641	78	4	through	through	ADP
bionys-641	78	5	two	two	NUM
bionys-641	78	6	major	major	ADJ
bionys-641	78	7	pathways	pathway	NOUN
bionys-641	78	8	(	(	PUNCT
bionys-641	78	9	nosalova	nosalova	X
bionys-641	78	10	et	et	PROPN
bionys-641	78	11	al	al	PROPN
bionys-641	78	12	.	.	PROPN
bionys-641	78	13	,	,	PUNCT
bionys-641	78	14	2023	2023	NUM
bionys-641	78	15	):	):	PUNCT
bionys-641	78	16	the	the	DET
bionys-641	78	17	intrinsic	intrinsic	ADJ
bionys-641	78	18	(	(	PUNCT
bionys-641	78	19	mitochondrial	mitochondrial	ADJ
bionys-641	78	20	)	)	PUNCT
bionys-641	78	21	pathway	pathway	NOUN
bionys-641	78	22	,	,	PUNCT
bionys-641	78	23	responsive	responsive	ADJ
bionys-641	78	24	to	to	ADP
bionys-641	78	25	intracellular	intracellular	ADJ
bionys-641	78	26	stressors	stressor	NOUN
bionys-641	78	27	such	such	ADJ
bionys-641	78	28	as	as	ADP
bionys-641	78	29	dna	dna	PROPN
bionys-641	78	30	damage	damage	NOUN
bionys-641	78	31	and	and	CCONJ
bionys-641	78	32	regulated	regulate	VERB
bionys-641	78	33	by	by	ADP
bionys-641	78	34	the	the	DET
bionys-641	78	35	b	b	NOUN
bionys-641	78	36	-	-	PUNCT
bionys-641	78	37	cell	cell	NOUN
bionys-641	78	38	lymphoma-2	lymphoma-2	NUM
bionys-641	78	39	(	(	PUNCT
bionys-641	78	40	bcl-2	bcl-2	NOUN
bionys-641	78	41	)	)	PUNCT
bionys-641	78	42	protein	protein	NOUN
bionys-641	78	43	family	family	NOUN
bionys-641	78	44	,	,	PUNCT
bionys-641	78	45	and	and	CCONJ
bionys-641	78	46	the	the	DET
bionys-641	78	47	extrinsic	extrinsic	ADJ
bionys-641	78	48	(	(	PUNCT
bionys-641	78	49	death	death	NOUN
bionys-641	78	50	receptor	receptor	NOUN
bionys-641	78	51	/	/	SYM
bionys-641	78	52	dr	dr	PROPN
bionys-641	78	53	)	)	PUNCT
bionys-641	78	54	pathway	pathway	NOUN
bionys-641	78	55	,	,	PUNCT
bionys-641	78	56	initiated	initiate	VERB
bionys-641	78	57	by	by	ADP
bionys-641	78	58	extracellular	extracellular	ADJ
bionys-641	78	59	ligands	ligand	NOUN
bionys-641	78	60	such	such	ADJ
bionys-641	78	61	as	as	ADP
bionys-641	78	62	tumor	tumor	NOUN
bionys-641	78	63	necrosis	necrosis	NOUN
bionys-641	78	64	factor	factor	NOUN
bionys-641	78	65	(	(	PUNCT
bionys-641	78	66	tnf	tnf	PROPN
bionys-641	78	67	)	)	PUNCT
bionys-641	78	68	or	or	CCONJ
bionys-641	78	69	fas	fas	PROPN
bionys-641	78	70	ligand	ligand	PROPN
bionys-641	78	71	(	(	PUNCT
bionys-641	78	72	fasl	fasl	PROPN
bionys-641	78	73	)	)	PUNCT
bionys-641	78	74	.	.	PUNCT
bionys-641	79	1	the	the	DET
bionys-641	79	2	complementary	complementary	ADJ
bionys-641	79	3	actions	action	NOUN
bionys-641	79	4	of	of	ADP
bionys-641	79	5	extrinsic	extrinsic	ADJ
bionys-641	79	6	and	and	CCONJ
bionys-641	79	7	intrinsic	intrinsic	ADJ
bionys-641	79	8	apoptotic	apoptotic	ADJ
bionys-641	79	9	pathways	pathway	NOUN
bionys-641	79	10	guarantee	guarantee	VERB
bionys-641	79	11	that	that	SCONJ
bionys-641	79	12	damaged	damage	VERB
bionys-641	79	13	cells	cell	NOUN
bionys-641	79	14	are	be	AUX
bionys-641	79	15	eliminated	eliminate	VERB
bionys-641	79	16	from	from	ADP
bionys-641	79	17	the	the	DET
bionys-641	79	18	body	body	NOUN
bionys-641	79	19	and	and	CCONJ
bionys-641	79	20	multicellular	multicellular	ADJ
bionys-641	79	21	organisms	organism	NOUN
bionys-641	79	22	continue	continue	VERB
bionys-641	79	23	to	to	PART
bionys-641	79	24	function	function	VERB
bionys-641	79	25	normally	normally	ADV
bionys-641	79	26	(	(	PUNCT
bionys-641	79	27	zhong	zhong	PROPN
bionys-641	79	28	et	et	PROPN
bionys-641	79	29	al	al	PROPN
bionys-641	79	30	.	.	PROPN
bionys-641	79	31	,	,	PUNCT
bionys-641	79	32	2020	2020	NUM
bionys-641	79	33	;	;	PUNCT
bionys-641	79	34	nosalova	nosalova	PROPN
bionys-641	79	35	biologica	biologica	PROPN
bionys-641	79	36	nyssana	nyssana	PROPN
bionys-641	79	37	●	●	PUNCT
bionys-641	79	38	16	16	NUM
bionys-641	79	39	(	(	PUNCT
bionys-641	79	40	2	2	NUM
bionys-641	79	41	)	)	PUNCT
bionys-641	79	42	december	december	PROPN
bionys-641	79	43	2025	2025	NUM
bionys-641	79	44	:	:	PUNCT
bionys-641	79	45	liana	liana	NOUN
bionys-641	79	46	et	et	PROPN
bionys-641	79	47	al	al	PROPN
bionys-641	79	48	.	.	PUNCT
bionys-641	80	1	●	●	PUNCT
bionys-641	80	2	cell	cell	NOUN
bionys-641	80	3	deaths	death	NOUN
bionys-641	80	4	and	and	CCONJ
bionys-641	80	5	their	their	PRON
bionys-641	80	6	associated	associate	VERB
bionys-641	80	7	mechanisms	mechanism	NOUN
bionys-641	80	8	et	et	NOUN
bionys-641	80	9	al	al	PROPN
bionys-641	80	10	.	.	PROPN
bionys-641	80	11	,	,	PUNCT
bionys-641	80	12	2023	2023	NUM
bionys-641	80	13	)	)	PUNCT
bionys-641	80	14	.	.	PUNCT
bionys-641	81	1	apoptosis	apoptosis	NOUN
bionys-641	81	2	regulation	regulation	NOUN
bionys-641	81	3	issues	issue	NOUN
bionys-641	81	4	can	can	AUX
bionys-641	81	5	result	result	VERB
bionys-641	81	6	in	in	ADP
bionys-641	81	7	pathological	pathological	ADJ
bionys-641	81	8	conditions	condition	NOUN
bionys-641	81	9	in	in	ADP
bionys-641	81	10	several	several	ADJ
bionys-641	81	11	diseases	disease	NOUN
bionys-641	81	12	.	.	PUNCT
bionys-641	82	1	for	for	ADP
bionys-641	82	2	instance	instance	NOUN
bionys-641	82	3	,	,	PUNCT
bionys-641	82	4	in	in	ADP
bionys-641	82	5	degenerative	degenerative	ADJ
bionys-641	82	6	illnesses	illness	NOUN
bionys-641	82	7	like	like	ADP
bionys-641	82	8	ad	ad	NOUN
bionys-641	82	9	,	,	PUNCT
bionys-641	82	10	where	where	SCONJ
bionys-641	82	11	caspase	caspase	PROPN
bionys-641	82	12	overactivation	overactivation	PROPN
bionys-641	82	13	—	—	PUNCT
bionys-641	82	14	a	a	DET
bionys-641	82	15	crucial	crucial	ADJ
bionys-641	82	16	class	class	NOUN
bionys-641	82	17	of	of	ADP
bionys-641	82	18	enzymes	enzyme	NOUN
bionys-641	82	19	implicated	implicate	VERB
bionys-641	82	20	as	as	ADP
bionys-641	82	21	an	an	DET
bionys-641	82	22	apoptosis	apoptosis	NOUN
bionys-641	82	23	driver	driver	NOUN
bionys-641	82	24	—	—	PUNCT
bionys-641	82	25	appears	appear	VERB
bionys-641	82	26	to	to	PART
bionys-641	82	27	be	be	AUX
bionys-641	82	28	the	the	DET
bionys-641	82	29	cause	cause	NOUN
bionys-641	82	30	of	of	ADP
bionys-641	82	31	neuronal	neuronal	ADJ
bionys-641	82	32	death	death	NOUN
bionys-641	82	33	(	(	PUNCT
bionys-641	82	34	sheffield	sheffield	PROPN
bionys-641	82	35	et	et	PROPN
bionys-641	82	36	al	al	PROPN
bionys-641	82	37	.	.	PROPN
bionys-641	82	38	,	,	PUNCT
bionys-641	82	39	2006	2006	NUM
bionys-641	82	40	)	)	PUNCT
bionys-641	82	41	.	.	PUNCT
bionys-641	83	1	this	this	PRON
bionys-641	83	2	is	be	AUX
bionys-641	83	3	also	also	ADV
bionys-641	83	4	a	a	DET
bionys-641	83	5	necessary	necessary	ADJ
bionys-641	83	6	process	process	NOUN
bionys-641	83	7	to	to	PART
bionys-641	83	8	prevent	prevent	VERB
bionys-641	83	9	malignancy	malignancy	NOUN
bionys-641	83	10	(	(	PUNCT
bionys-641	83	11	abastado	abastado	NOUN
bionys-641	83	12	,	,	PUNCT
bionys-641	83	13	2015	2015	NUM
bionys-641	83	14	)	)	PUNCT
bionys-641	83	15	.	.	PUNCT
bionys-641	84	1	the	the	DET
bionys-641	84	2	intrinsic	intrinsic	ADJ
bionys-641	84	3	pathway	pathway	NOUN
bionys-641	84	4	of	of	ADP
bionys-641	84	5	apoptosis	apoptosis	NOUN
bionys-641	84	6	can	can	AUX
bionys-641	84	7	be	be	AUX
bionys-641	84	8	initiated	initiate	VERB
bionys-641	84	9	from	from	ADP
bionys-641	84	10	a	a	DET
bionys-641	84	11	positive	positive	ADJ
bionys-641	84	12	or	or	CCONJ
bionys-641	84	13	negative	negative	ADJ
bionys-641	84	14	process	process	NOUN
bionys-641	84	15	and	and	CCONJ
bionys-641	84	16	depends	depend	VERB
bionys-641	84	17	on	on	ADP
bionys-641	84	18	chemicals	chemical	NOUN
bionys-641	84	19	generated	generate	VERB
bionys-641	84	20	from	from	ADP
bionys-641	84	21	the	the	DET
bionys-641	84	22	mitochondria	mitochondria	NOUN
bionys-641	84	23	.	.	PUNCT
bionys-641	85	1	the	the	DET
bionys-641	85	2	lack	lack	NOUN
bionys-641	85	3	of	of	ADP
bionys-641	85	4	growth	growth	NOUN
bionys-641	85	5	factors	factor	NOUN
bionys-641	85	6	,	,	PUNCT
bionys-641	85	7	hormones	hormone	NOUN
bionys-641	85	8	,	,	PUNCT
bionys-641	85	9	and	and	CCONJ
bionys-641	85	10	cytokines	cytokine	NOUN
bionys-641	85	11	in	in	ADP
bionys-641	85	12	the	the	DET
bionys-641	85	13	cell	cell	NOUN
bionys-641	85	14	's	's	PART
bionys-641	85	15	surroundings	surrounding	NOUN
bionys-641	85	16	produces	produce	VERB
bionys-641	85	17	negative	negative	ADJ
bionys-641	85	18	signals	signal	NOUN
bionys-641	85	19	(	(	PUNCT
bionys-641	85	20	orzaez	orzaez	NOUN
bionys-641	85	21	et	et	PROPN
bionys-641	85	22	al	al	PROPN
bionys-641	85	23	.	.	PROPN
bionys-641	85	24	,	,	PUNCT
bionys-641	85	25	2009	2009	NUM
bionys-641	85	26	)	)	PUNCT
bionys-641	85	27	.	.	PUNCT
bionys-641	86	1	in	in	ADP
bionys-641	86	2	addition	addition	NOUN
bionys-641	86	3	,	,	PUNCT
bionys-641	86	4	several	several	ADJ
bionys-641	86	5	cellular	cellular	ADJ
bionys-641	86	6	pro	pro	ADJ
bionys-641	86	7	-	-	ADJ
bionys-641	86	8	apoptotic	apoptotic	ADJ
bionys-641	86	9	molecules	molecule	NOUN
bionys-641	86	10	,	,	PUNCT
bionys-641	86	11	such	such	ADJ
bionys-641	86	12	as	as	ADP
bionys-641	86	13	puma	puma	PROPN
bionys-641	86	14	,	,	PUNCT
bionys-641	86	15	noxa	noxa	NOUN
bionys-641	86	16	,	,	PUNCT
bionys-641	86	17	and	and	CCONJ
bionys-641	86	18	bax	bax	PROPN
bionys-641	86	19	,	,	PUNCT
bionys-641	86	20	which	which	PRON
bionys-641	86	21	are	be	AUX
bionys-641	86	22	typically	typically	ADV
bionys-641	86	23	suppressed	suppress	VERB
bionys-641	86	24	in	in	ADP
bionys-641	86	25	a	a	DET
bionys-641	86	26	physiological	physiological	ADJ
bionys-641	86	27	state	state	NOUN
bionys-641	86	28	,	,	PUNCT
bionys-641	86	29	become	become	VERB
bionys-641	86	30	active	active	ADJ
bionys-641	86	31	and	and	CCONJ
bionys-641	86	32	are	be	AUX
bionys-641	86	33	able	able	ADJ
bionys-641	86	34	to	to	PART
bionys-641	86	35	start	start	VERB
bionys-641	86	36	apoptosis	apoptosis	NOUN
bionys-641	86	37	after	after	ADP
bionys-641	86	38	reaching	reach	VERB
bionys-641	86	39	the	the	DET
bionys-641	86	40	activation	activation	NOUN
bionys-641	86	41	threshold	threshold	NOUN
bionys-641	86	42	and	and	CCONJ
bionys-641	86	43	with	with	ADP
bionys-641	86	44	a	a	DET
bionys-641	86	45	deficiency	deficiency	NOUN
bionys-641	86	46	of	of	ADP
bionys-641	86	47	the	the	DET
bionys-641	86	48	previously	previously	ADV
bionys-641	86	49	mentioned	mention	VERB
bionys-641	86	50	pro	pro	ADJ
bionys-641	86	51	-	-	ADJ
bionys-641	86	52	survival	survival	ADJ
bionys-641	86	53	signals	signal	NOUN
bionys-641	86	54	(	(	PUNCT
bionys-641	86	55	zhang	zhang	X
bionys-641	86	56	et	et	PROPN
bionys-641	86	57	al	al	PROPN
bionys-641	86	58	.	.	PROPN
bionys-641	86	59	,	,	PUNCT
bionys-641	86	60	2016	2016	NUM
bionys-641	86	61	)	)	PUNCT
bionys-641	86	62	.	.	PUNCT
bionys-641	87	1	positive	positive	ADJ
bionys-641	87	2	situations	situation	NOUN
bionys-641	87	3	,	,	PUNCT
bionys-641	87	4	including	include	VERB
bionys-641	87	5	hypoxia	hypoxia	NOUN
bionys-641	87	6	,	,	PUNCT
bionys-641	87	7	poisons	poison	NOUN
bionys-641	87	8	,	,	PUNCT
bionys-641	87	9	radiation	radiation	NOUN
bionys-641	87	10	,	,	PUNCT
bionys-641	87	11	reactive	reactive	ADJ
bionys-641	87	12	oxygen	oxygen	NOUN
bionys-641	87	13	species	specie	NOUN
bionys-641	87	14	overproduction	overproduction	NOUN
bionys-641	87	15	,	,	PUNCT
bionys-641	87	16	viruses	virus	NOUN
bionys-641	87	17	,	,	PUNCT
bionys-641	87	18	and	and	CCONJ
bionys-641	87	19	different	different	ADJ
bionys-641	87	20	hazardous	hazardous	ADJ
bionys-641	87	21	agents	agent	NOUN
bionys-641	87	22	,	,	PUNCT
bionys-641	87	23	are	be	AUX
bionys-641	87	24	additional	additional	ADJ
bionys-641	87	25	variables	variable	NOUN
bionys-641	87	26	that	that	SCONJ
bionys-641	87	27	trigger	trigger	NOUN
bionys-641	87	28	apoptosis	apoptosis	NOUN
bionys-641	87	29	(	(	PUNCT
bionys-641	87	30	guhl	guhl	X
bionys-641	87	31	et	et	PROPN
bionys-641	87	32	al	al	PROPN
bionys-641	87	33	.	.	PROPN
bionys-641	87	34	,	,	PUNCT
bionys-641	87	35	2003	2003	NUM
bionys-641	87	36	;	;	PUNCT
bionys-641	87	37	sun	sun	PROPN
bionys-641	87	38	&	&	CCONJ
bionys-641	87	39	mei	mei	PROPN
bionys-641	87	40	,	,	PUNCT
bionys-641	87	41	2024	2024	NUM
bionys-641	87	42	)	)	PUNCT
bionys-641	87	43	.	.	PUNCT
bionys-641	88	1	two	two	NUM
bionys-641	88	2	subsets	subset	NOUN
bionys-641	88	3	of	of	ADP
bionys-641	88	4	bcl-2	bcl-2	NOUN
bionys-641	88	5	proteins	protein	NOUN
bionys-641	88	6	known	know	VERB
bionys-641	88	7	as	as	ADP
bionys-641	88	8	antiapoptotic	antiapoptotic	ADJ
bionys-641	88	9	proteins	protein	NOUN
bionys-641	88	10	,	,	PUNCT
bionys-641	88	11	including	include	VERB
bionys-641	88	12	bcl-2	bcl-2	NOUN
bionys-641	88	13	,	,	PUNCT
bionys-641	88	14	bcl	bcl	PROPN
bionys-641	88	15	-	-	PROPN
bionys-641	88	16	xl	xl	PROPN
bionys-641	88	17	,	,	PUNCT
bionys-641	88	18	bcl	bcl	PROPN
bionys-641	88	19	-	-	PUNCT
bionys-641	88	20	w	w	PROPN
bionys-641	88	21	,	,	PUNCT
bionys-641	88	22	bfl-1	bfl-1	X
bionys-641	88	23	,	,	PUNCT
bionys-641	88	24	and	and	CCONJ
bionys-641	88	25	mcl-1	mcl-1	NUM
bionys-641	88	26	,	,	PUNCT
bionys-641	88	27	control	control	VERB
bionys-641	88	28	the	the	DET
bionys-641	88	29	intrinsic	intrinsic	ADJ
bionys-641	88	30	pathway	pathway	NOUN
bionys-641	88	31	(	(	PUNCT
bionys-641	88	32	zhu	zhu	X
bionys-641	88	33	et	et	PROPN
bionys-641	88	34	al	al	PROPN
bionys-641	88	35	.	.	PROPN
bionys-641	88	36	,	,	PUNCT
bionys-641	88	37	2007	2007	NUM
bionys-641	88	38	)	)	PUNCT
bionys-641	88	39	.	.	PUNCT
bionys-641	89	1	these	these	DET
bionys-641	89	2	substances	substance	NOUN
bionys-641	89	3	control	control	VERB
bionys-641	89	4	apoptosis	apoptosis	NOUN
bionys-641	89	5	by	by	ADP
bionys-641	89	6	preventing	prevent	VERB
bionys-641	89	7	the	the	DET
bionys-641	89	8	release	release	NOUN
bionys-641	89	9	of	of	ADP
bionys-641	89	10	cytochrome	cytochrome	NOUN
bionys-641	89	11	c	c	NOUN
bionys-641	89	12	(	(	PUNCT
bionys-641	89	13	cytc	cytc	INTJ
bionys-641	89	14	)	)	PUNCT
bionys-641	89	15	from	from	ADP
bionys-641	89	16	mitochondria	mitochondria	PROPN
bionys-641	89	17	.	.	PUNCT
bionys-641	90	1	on	on	ADP
bionys-641	90	2	the	the	DET
bionys-641	90	3	other	other	ADJ
bionys-641	90	4	hand	hand	NOUN
bionys-641	90	5	,	,	PUNCT
bionys-641	90	6	apoptosis	apoptosis	NOUN
bionys-641	90	7	is	be	AUX
bionys-641	90	8	regulated	regulate	VERB
bionys-641	90	9	by	by	ADP
bionys-641	90	10	pro	pro	ADJ
bionys-641	90	11	-	-	ADJ
bionys-641	90	12	apoptotic	apoptotic	ADJ
bionys-641	90	13	proteins	protein	NOUN
bionys-641	90	14	like	like	ADP
bionys-641	90	15	hrk	hrk	PROPN
bionys-641	90	16	,	,	PUNCT
bionys-641	90	17	bak	bak	NOUN
bionys-641	90	18	,	,	PUNCT
bionys-641	90	19	bad	bad	ADJ
bionys-641	90	20	,	,	PUNCT
bionys-641	90	21	bcl	bcl	PROPN
bionys-641	90	22	-	-	PUNCT
bionys-641	90	23	xs	xs	PROPN
bionys-641	90	24	,	,	PUNCT
bionys-641	90	25	bid	bid	NOUN
bionys-641	90	26	,	,	PUNCT
bionys-641	90	27	bik	bik	PROPN
bionys-641	90	28	,	,	PUNCT
bionys-641	90	29	and	and	CCONJ
bionys-641	90	30	bim	bim	NOUN
bionys-641	90	31	,	,	PUNCT
bionys-641	90	32	which	which	PRON
bionys-641	90	33	release	release	VERB
bionys-641	90	34	cytc	cytc	ADV
bionys-641	90	35	from	from	ADP
bionys-641	90	36	mitochondria	mitochondria	PROPN
bionys-641	90	37	(	(	PUNCT
bionys-641	90	38	liu	liu	PROPN
bionys-641	90	39	et	et	PROPN
bionys-641	90	40	al	al	PROPN
bionys-641	90	41	.	.	PROPN
bionys-641	90	42	,	,	PUNCT
bionys-641	90	43	2013	2013	NUM
bionys-641	90	44	)	)	PUNCT
bionys-641	90	45	.	.	PUNCT
bionys-641	91	1	caspases	caspase	NOUN
bionys-641	91	2	8	8	NUM
bionys-641	91	3	and	and	CCONJ
bionys-641	91	4	9	9	NUM
bionys-641	91	5	are	be	AUX
bionys-641	91	6	activated	activate	VERB
bionys-641	91	7	,	,	PUNCT
bionys-641	91	8	and	and	CCONJ
bionys-641	91	9	apoptosomes	apoptosome	NOUN
bionys-641	91	10	are	be	AUX
bionys-641	91	11	formed	form	VERB
bionys-641	91	12	due	due	ADP
bionys-641	91	13	to	to	ADP
bionys-641	91	14	the	the	DET
bionys-641	91	15	release	release	NOUN
bionys-641	91	16	of	of	ADP
bionys-641	91	17	cytc	cytc	NOUN
bionys-641	91	18	from	from	ADP
bionys-641	91	19	mitochondria	mitochondria	PROPN
bionys-641	91	20	.	.	PUNCT
bionys-641	92	1	cell	cell	NOUN
bionys-641	92	2	death	death	NOUN
bionys-641	92	3	is	be	AUX
bionys-641	92	4	caused	cause	VERB
bionys-641	92	5	by	by	ADP
bionys-641	92	6	the	the	DET
bionys-641	92	7	activation	activation	NOUN
bionys-641	92	8	of	of	ADP
bionys-641	92	9	caspase-3	caspase-3	NUM
bionys-641	92	10	by	by	ADP
bionys-641	92	11	these	these	DET
bionys-641	92	12	activated	activate	VERB
bionys-641	92	13	caspases	caspase	NOUN
bionys-641	92	14	(	(	PUNCT
bionys-641	92	15	aral	aral	PROPN
bionys-641	92	16	et	et	PROPN
bionys-641	92	17	al	al	PROPN
bionys-641	92	18	.	.	PROPN
bionys-641	92	19	,	,	PUNCT
bionys-641	92	20	2019	2019	NUM
bionys-641	92	21	)	)	PUNCT
bionys-641	92	22	.	.	PUNCT
bionys-641	93	1	the	the	DET
bionys-641	93	2	extrinsic	extrinsic	ADJ
bionys-641	93	3	mechanism	mechanism	NOUN
bionys-641	93	4	of	of	ADP
bionys-641	93	5	apoptosis	apoptosis	NOUN
bionys-641	93	6	involves	involve	VERB
bionys-641	93	7	specific	specific	ADJ
bionys-641	93	8	receptors	receptor	NOUN
bionys-641	93	9	binding	bind	VERB
bionys-641	93	10	to	to	ADP
bionys-641	93	11	ligands	ligand	NOUN
bionys-641	93	12	,	,	PUNCT
bionys-641	93	13	forming	form	VERB
bionys-641	93	14	a	a	DET
bionys-641	93	15	disc	disc	NOUN
bionys-641	93	16	complex	complex	NOUN
bionys-641	93	17	,	,	PUNCT
bionys-641	93	18	and	and	CCONJ
bionys-641	93	19	activating	activate	VERB
bionys-641	93	20	caspases	caspase	NOUN
bionys-641	93	21	.	.	PUNCT
bionys-641	94	1	this	this	DET
bionys-641	94	2	pathway	pathway	NOUN
bionys-641	94	3	is	be	AUX
bionys-641	94	4	initiated	initiate	VERB
bionys-641	94	5	when	when	SCONJ
bionys-641	94	6	nk	nk	PROPN
bionys-641	94	7	cells	cell	NOUN
bionys-641	94	8	or	or	CCONJ
bionys-641	94	9	macrophages	macrophage	NOUN
bionys-641	94	10	produce	produce	VERB
bionys-641	94	11	death	death	NOUN
bionys-641	94	12	ligands	ligand	NOUN
bionys-641	94	13	that	that	PRON
bionys-641	94	14	bind	bind	VERB
bionys-641	94	15	to	to	ADP
bionys-641	94	16	the	the	DET
bionys-641	94	17	dr	dr	PROPN
bionys-641	94	18	on	on	ADP
bionys-641	94	19	the	the	DET
bionys-641	94	20	target	target	NOUN
bionys-641	94	21	cell	cell	NOUN
bionys-641	94	22	membrane	membrane	NOUN
bionys-641	94	23	(	(	PUNCT
bionys-641	94	24	schulze	schulze	NOUN
bionys-641	94	25	-	-	PUNCT
bionys-641	94	26	osthoff	osthoff	NOUN
bionys-641	94	27	et	et	PROPN
bionys-641	94	28	al	al	PROPN
bionys-641	94	29	.	.	PROPN
bionys-641	94	30	,	,	PUNCT
bionys-641	94	31	1998	1998	NUM
bionys-641	94	32	;	;	PUNCT
bionys-641	94	33	park	park	NOUN
bionys-641	94	34	et	et	PROPN
bionys-641	94	35	al	al	PROPN
bionys-641	94	36	.	.	PROPN
bionys-641	94	37	,	,	PUNCT
bionys-641	94	38	2012	2012	NUM
bionys-641	94	39	)	)	PUNCT
bionys-641	94	40	.	.	PUNCT
bionys-641	95	1	the	the	DET
bionys-641	95	2	role	role	NOUN
bionys-641	95	3	of	of	ADP
bionys-641	95	4	these	these	DET
bionys-641	95	5	death	death	NOUN
bionys-641	95	6	receptors	receptor	NOUN
bionys-641	95	7	in	in	ADP
bionys-641	95	8	the	the	DET
bionys-641	95	9	extrinsic	extrinsic	ADJ
bionys-641	95	10	pathway	pathway	NOUN
bionys-641	95	11	is	be	AUX
bionys-641	95	12	significant	significant	ADJ
bionys-641	95	13	,	,	PUNCT
bionys-641	95	14	as	as	SCONJ
bionys-641	95	15	they	they	PRON
bionys-641	95	16	trigger	trigger	VERB
bionys-641	95	17	the	the	DET
bionys-641	95	18	pathway	pathway	NOUN
bionys-641	95	19	by	by	ADP
bionys-641	95	20	activating	activate	VERB
bionys-641	95	21	procaspase	procaspase	NOUN
bionys-641	95	22	8	8	NUM
bionys-641	95	23	to	to	ADP
bionys-641	95	24	caspase	caspase	PROPN
bionys-641	95	25	8	8	NUM
bionys-641	95	26	(	(	PUNCT
bionys-641	95	27	schulze	schulze	NOUN
bionys-641	95	28	-	-	PUNCT
bionys-641	95	29	osthoff	osthoff	NOUN
bionys-641	95	30	et	et	PROPN
bionys-641	95	31	al	al	PROPN
bionys-641	95	32	.	.	PROPN
bionys-641	95	33	,	,	PUNCT
bionys-641	95	34	1998	1998	NUM
bionys-641	95	35	)	)	PUNCT
bionys-641	95	36	.	.	PUNCT
bionys-641	96	1	there	there	PRON
bionys-641	96	2	are	be	VERB
bionys-641	96	3	several	several	ADJ
bionys-641	96	4	dr	dr	PROPN
bionys-641	96	5	types	type	NOUN
bionys-641	96	6	,	,	PUNCT
bionys-641	96	7	such	such	ADJ
bionys-641	96	8	as	as	ADP
bionys-641	96	9	cd95	cd95	PROPN
bionys-641	96	10	(	(	PUNCT
bionys-641	96	11	also	also	ADV
bionys-641	96	12	known	know	VERB
bionys-641	96	13	as	as	ADP
bionys-641	96	14	fas	fas	NOUN
bionys-641	96	15	and	and	CCONJ
bionys-641	96	16	apo-1	apo-1	NOUN
bionys-641	96	17	,	,	PUNCT
bionys-641	96	18	tumor	tumor	NOUN
bionys-641	96	19	necrosis	necrosis	NOUN
bionys-641	96	20	factor	factor	NOUN
bionys-641	96	21	/	/	SYM
bionys-641	96	22	tnf	tnf	PROPN
bionys-641	96	23	receptor	receptor	NOUN
bionys-641	96	24	1	1	NUM
bionys-641	96	25	(	(	PUNCT
bionys-641	96	26	tnfr1	tnfr1	NOUN
bionys-641	96	27	)	)	PUNCT
bionys-641	96	28	,	,	PUNCT
bionys-641	96	29	tnf	tnf	PROPN
bionys-641	96	30	receptor	receptor	NOUN
bionys-641	96	31	superfamily	superfamily	NOUN
bionys-641	96	32	member	member	NOUN
bionys-641	96	33	25	25	NUM
bionys-641	96	34	(	(	PUNCT
bionys-641	96	35	tnfrsf25)/dr3	tnfrsf25)/dr3	PROPN
bionys-641	96	36	,	,	PUNCT
bionys-641	96	37	tnf	tnf	PROPN
bionys-641	96	38	-	-	PUNCT
bionys-641	96	39	related	relate	VERB
bionys-641	96	40	apoptosis	apoptosis	NOUN
bionys-641	96	41	-	-	PUNCT
bionys-641	96	42	inducing	induce	VERB
bionys-641	96	43	ligand	ligand	ADJ
bionys-641	96	44	receptor	receptor	NOUN
bionys-641	96	45	1	1	NUM
bionys-641	96	46	(	(	PUNCT
bionys-641	96	47	trail	trail	NOUN
bionys-641	96	48	-	-	PUNCT
bionys-641	96	49	r1)/dr4	r1)/dr4	PROPN
bionys-641	96	50	,	,	PUNCT
bionys-641	96	51	and	and	CCONJ
bionys-641	96	52	tnf	tnf	PROPN
bionys-641	96	53	-	-	PUNCT
bionys-641	96	54	related	relate	VERB
bionys-641	96	55	apoptosisinducing	apoptosisinducing	NOUN
bionys-641	96	56	ligand	ligand	NOUN
bionys-641	96	57	receptor	receptor	NOUN
bionys-641	96	58	2	2	NUM
bionys-641	96	59	(	(	PUNCT
bionys-641	96	60	trail	trail	NOUN
bionys-641	96	61	-	-	PUNCT
bionys-641	96	62	r2)/dr5	r2)/dr5	NOUN
bionys-641	96	63	(	(	PUNCT
bionys-641	96	64	fossati	fossati	PROPN
bionys-641	96	65	et	et	PROPN
bionys-641	96	66	al	al	PROPN
bionys-641	96	67	.	.	PROPN
bionys-641	96	68	,	,	PUNCT
bionys-641	96	69	2012	2012	NUM
bionys-641	96	70	;	;	PUNCT
bionys-641	96	71	bittner	bittner	PROPN
bionys-641	96	72	et	et	PROPN
bionys-641	96	73	al	al	PROPN
bionys-641	96	74	.	.	PROPN
bionys-641	96	75	,	,	PUNCT
bionys-641	96	76	2016	2016	NUM
bionys-641	96	77	)	)	PUNCT
bionys-641	96	78	.	.	PUNCT
bionys-641	97	1	however	however	ADV
bionys-641	97	2	,	,	PUNCT
bionys-641	97	3	the	the	DET
bionys-641	97	4	first	first	ADJ
bionys-641	97	5	two	two	NUM
bionys-641	97	6	receptors	receptor	NOUN
bionys-641	97	7	are	be	AUX
bionys-641	97	8	the	the	DET
bionys-641	97	9	most	most	ADV
bionys-641	97	10	well	well	ADV
bionys-641	97	11	-	-	PUNCT
bionys-641	97	12	known	know	VERB
bionys-641	97	13	ones	one	NOUN
bionys-641	97	14	.	.	PUNCT
bionys-641	98	1	these	these	DET
bionys-641	98	2	receptors	receptor	NOUN
bionys-641	98	3	contain	contain	VERB
bionys-641	98	4	a	a	DET
bionys-641	98	5	death	death	NOUN
bionys-641	98	6	domain	domain	NOUN
bionys-641	98	7	,	,	PUNCT
bionys-641	98	8	which	which	PRON
bionys-641	98	9	requires	require	VERB
bionys-641	98	10	adaptor	adaptor	NOUN
bionys-641	98	11	proteins	protein	NOUN
bionys-641	98	12	to	to	PART
bionys-641	98	13	operate	operate	VERB
bionys-641	98	14	properly	properly	ADV
bionys-641	98	15	,	,	PUNCT
bionys-641	98	16	such	such	ADJ
bionys-641	98	17	as	as	ADP
bionys-641	98	18	the	the	DET
bionys-641	98	19	fas	fas	ADJ
bionys-641	98	20	-	-	PUNCT
bionys-641	98	21	associated	associate	VERB
bionys-641	98	22	death	death	NOUN
bionys-641	98	23	domain	domain	NOUN
bionys-641	98	24	(	(	PUNCT
bionys-641	98	25	fadd	fadd	NOUN
bionys-641	98	26	)	)	PUNCT
bionys-641	98	27	and	and	CCONJ
bionys-641	98	28	tnf	tnf	PROPN
bionys-641	98	29	receptor	receptor	NOUN
bionys-641	98	30	-	-	PUNCT
bionys-641	98	31	associated	associate	VERB
bionys-641	98	32	death	death	NOUN
bionys-641	98	33	domain	domain	NOUN
bionys-641	98	34	(	(	PUNCT
bionys-641	98	35	tradd	tradd	NOUN
bionys-641	98	36	)	)	PUNCT
bionys-641	98	37	.	.	PUNCT
bionys-641	99	1	these	these	DET
bionys-641	99	2	proteins	protein	NOUN
bionys-641	99	3	bind	bind	VERB
bionys-641	99	4	to	to	ADP
bionys-641	99	5	the	the	DET
bionys-641	99	6	death	death	NOUN
bionys-641	99	7	receptor	receptor	NOUN
bionys-641	99	8	,	,	PUNCT
bionys-641	99	9	strengthening	strengthen	VERB
bionys-641	99	10	the	the	DET
bionys-641	99	11	ligand	ligand	ADJ
bionys-641	99	12	-	-	PUNCT
bionys-641	99	13	receptor	receptor	NOUN
bionys-641	99	14	-	-	PUNCT
bionys-641	99	15	adaptor	adaptor	NOUN
bionys-641	99	16	protein	protein	NOUN
bionys-641	99	17	complex	complex	NOUN
bionys-641	99	18	known	know	VERB
bionys-641	99	19	as	as	ADP
bionys-641	99	20	the	the	DET
bionys-641	99	21	death	death	NOUN
bionys-641	99	22	-	-	PUNCT
bionys-641	99	23	inducing	induce	VERB
bionys-641	99	24	signaling	signal	VERB
bionys-641	99	25	complex	complex	ADJ
bionys-641	99	26	(	(	PUNCT
bionys-641	99	27	disc	disc	NOUN
bionys-641	99	28	)	)	PUNCT
bionys-641	99	29	(	(	PUNCT
bionys-641	99	30	fossati	fossati	PROPN
bionys-641	99	31	et	et	PROPN
bionys-641	99	32	al	al	PROPN
bionys-641	99	33	.	.	PROPN
bionys-641	99	34	,	,	PUNCT
bionys-641	99	35	2012	2012	NUM
bionys-641	99	36	;	;	PUNCT
bionys-641	99	37	cavalcante	cavalcante	VERB
bionys-641	99	38	et	et	PROPN
bionys-641	99	39	al	al	PROPN
bionys-641	99	40	.	.	PROPN
bionys-641	99	41	,	,	PUNCT
bionys-641	99	42	2019	2019	NUM
bionys-641	99	43	)	)	PUNCT
bionys-641	99	44	.	.	PUNCT
bionys-641	100	1	disc	disc	NOUN
bionys-641	100	2	then	then	ADV
bionys-641	100	3	activates	activate	VERB
bionys-641	100	4	procaspase	procaspase	NOUN
bionys-641	100	5	8	8	NUM
bionys-641	100	6	,	,	PUNCT
bionys-641	100	7	which	which	PRON
bionys-641	100	8	later	later	ADV
bionys-641	100	9	activates	activate	VERB
bionys-641	100	10	fig	fig	NOUN
bionys-641	100	11	.	.	PUNCT
bionys-641	101	1	2	2	X
bionys-641	101	2	.	.	X
bionys-641	101	3	apoptosis	apoptosis	NOUN
bionys-641	101	4	process	process	NOUN
bionys-641	101	5	biologica	biologica	PROPN
bionys-641	101	6	nyssana	nyssana	PROPN
bionys-641	102	1	●	●	PUNCT
bionys-641	102	2	16	16	NUM
bionys-641	102	3	(	(	PUNCT
bionys-641	102	4	2	2	NUM
bionys-641	102	5	)	)	PUNCT
bionys-641	102	6	december	december	PROPN
bionys-641	102	7	2025	2025	NUM
bionys-641	102	8	:	:	PUNCT
bionys-641	102	9	liana	liana	NOUN
bionys-641	102	10	et	et	PROPN
bionys-641	102	11	al	al	PROPN
bionys-641	102	12	.	.	PUNCT
bionys-641	103	1	●	●	PUNCT
bionys-641	103	2	cell	cell	NOUN
bionys-641	103	3	deaths	death	NOUN
bionys-641	103	4	and	and	CCONJ
bionys-641	103	5	their	their	PRON
bionys-641	103	6	associated	associate	VERB
bionys-641	103	7	mechanisms	mechanism	NOUN
bionys-641	103	8	following	follow	VERB
bionys-641	103	9	phosphorylation	phosphorylation	NOUN
bionys-641	103	10	,	,	PUNCT
bionys-641	103	11	mlkl	mlkl	PROPN
bionys-641	103	12	oligomerizes	oligomerize	NOUN
bionys-641	103	13	and	and	CCONJ
bionys-641	103	14	shifts	shift	NOUN
bionys-641	103	15	from	from	ADP
bionys-641	103	16	the	the	DET
bionys-641	103	17	cytoplasm	cytoplasm	NOUN
bionys-641	103	18	to	to	ADP
bionys-641	103	19	the	the	DET
bionys-641	103	20	cell	cell	NOUN
bionys-641	103	21	membrane	membrane	NOUN
bionys-641	103	22	.	.	PUNCT
bionys-641	104	1	this	this	PRON
bionys-641	104	2	causes	cause	VERB
bionys-641	104	3	membrane	membrane	NOUN
bionys-641	104	4	permeabilization	permeabilization	NOUN
bionys-641	104	5	,	,	PUNCT
bionys-641	104	6	probably	probably	ADV
bionys-641	104	7	owing	owe	VERB
bionys-641	104	8	to	to	ADP
bionys-641	104	9	mlkl	mlkl	PROPN
bionys-641	104	10	attachment	attachment	NOUN
bionys-641	104	11	to	to	ADP
bionys-641	104	12	phosphatidylinositol	phosphatidylinositol	NOUN
bionys-641	104	13	lipids	lipid	NOUN
bionys-641	104	14	and	and	CCONJ
bionys-641	104	15	cardiolipin	cardiolipin	NOUN
bionys-641	104	16	,	,	PUNCT
bionys-641	104	17	which	which	PRON
bionys-641	104	18	results	result	VERB
bionys-641	104	19	in	in	ADP
bionys-641	104	20	cell	cell	NOUN
bionys-641	104	21	death	death	NOUN
bionys-641	104	22	(	(	PUNCT
bionys-641	104	23	loftus	loftus	PROPN
bionys-641	104	24	et	et	PROPN
bionys-641	104	25	al	al	PROPN
bionys-641	104	26	.	.	PROPN
bionys-641	104	27	,	,	PUNCT
bionys-641	104	28	2022	2022	NUM
bionys-641	104	29	)	)	PUNCT
bionys-641	104	30	.	.	PUNCT
bionys-641	105	1	ferroptosis	ferroptosis	NOUN
bionys-641	105	2	ferroptosis	ferroptosis	PROPN
bionys-641	105	3	is	be	AUX
bionys-641	105	4	a	a	DET
bionys-641	105	5	unique	unique	ADJ
bionys-641	105	6	type	type	NOUN
bionys-641	105	7	of	of	ADP
bionys-641	105	8	rcd	rcd	PROPN
bionys-641	105	9	defined	define	VERB
bionys-641	105	10	by	by	ADP
bionys-641	105	11	the	the	DET
bionys-641	105	12	accumulation	accumulation	NOUN
bionys-641	105	13	of	of	ADP
bionys-641	105	14	lipid	lipid	ADJ
bionys-641	105	15	peroxides	peroxide	NOUN
bionys-641	105	16	to	to	ADP
bionys-641	105	17	fatal	fatal	ADJ
bionys-641	105	18	amounts	amount	NOUN
bionys-641	105	19	based	base	VERB
bionys-641	105	20	on	on	ADP
bionys-641	105	21	an	an	DET
bionys-641	105	22	iron	iron	NOUN
bionys-641	105	23	-	-	PUNCT
bionys-641	105	24	dependent	dependent	ADJ
bionys-641	105	25	process	process	NOUN
bionys-641	105	26	(	(	PUNCT
bionys-641	105	27	miao	miao	NOUN
bionys-641	105	28	et	et	PROPN
bionys-641	105	29	al	al	PROPN
bionys-641	105	30	.	.	PROPN
bionys-641	105	31	,	,	PUNCT
bionys-641	105	32	2023	2023	NUM
bionys-641	105	33	)	)	PUNCT
bionys-641	105	34	.	.	PUNCT
bionys-641	106	1	it	it	PRON
bionys-641	106	2	is	be	AUX
bionys-641	106	3	distinguished	distinguish	VERB
bionys-641	106	4	biochemically	biochemically	ADV
bionys-641	106	5	and	and	CCONJ
bionys-641	106	6	structurally	structurally	ADV
bionys-641	106	7	from	from	ADP
bionys-641	106	8	other	other	ADJ
bionys-641	106	9	forms	form	NOUN
bionys-641	106	10	of	of	ADP
bionys-641	106	11	cell	cell	NOUN
bionys-641	106	12	death	death	NOUN
bionys-641	106	13	and	and	CCONJ
bionys-641	106	14	is	be	AUX
bionys-641	106	15	typified	typify	VERB
bionys-641	106	16	by	by	ADP
bionys-641	106	17	compression	compression	NOUN
bionys-641	106	18	of	of	ADP
bionys-641	106	19	the	the	DET
bionys-641	106	20	mitochondria	mitochondria	NOUN
bionys-641	106	21	and	and	CCONJ
bionys-641	106	22	greater	great	ADJ
bionys-641	106	23	cellular	cellular	ADJ
bionys-641	106	24	membrane	membrane	NOUN
bionys-641	106	25	density	density	NOUN
bionys-641	106	26	with	with	ADP
bionys-641	106	27	sparing	sparing	NOUN
bionys-641	106	28	of	of	ADP
bionys-641	106	29	the	the	DET
bionys-641	106	30	nucleus	nucleus	NOUN
bionys-641	106	31	.	.	PUNCT
bionys-641	107	1	ferroptosis	ferroptosis	PROPN
bionys-641	107	2	is	be	AUX
bionys-641	107	3	caused	cause	VERB
bionys-641	107	4	when	when	SCONJ
bionys-641	107	5	the	the	DET
bionys-641	107	6	action	action	NOUN
bionys-641	107	7	of	of	ADP
bionys-641	107	8	proferroptotic	proferroptotic	ADJ
bionys-641	107	9	agents	agent	NOUN
bionys-641	107	10	(	(	PUNCT
bionys-641	107	11	such	such	ADJ
bionys-641	107	12	as	as	ADP
bionys-641	107	13	iron	iron	NOUN
bionys-641	107	14	and	and	CCONJ
bionys-641	107	15	polyunsaturated	polyunsaturated	ADJ
bionys-641	107	16	fatty	fatty	NOUN
bionys-641	107	17	acids	acid	NOUN
bionys-641	107	18	[	[	X
bionys-641	107	19	pufas	pufas	NOUN
bionys-641	107	20	]	]	PUNCT
bionys-641	107	21	)	)	PUNCT
bionys-641	107	22	and	and	CCONJ
bionys-641	107	23	anti	anti	ADJ
bionys-641	107	24	-	-	ADJ
bionys-641	107	25	ferroptotic	ferroptotic	ADJ
bionys-641	107	26	protection	protection	NOUN
bionys-641	107	27	mechanisms	mechanism	NOUN
bionys-641	107	28	are	be	AUX
bionys-641	107	29	unmatched	unmatched	ADJ
bionys-641	107	30	.	.	PUNCT
bionys-641	108	1	glutathione	glutathione	NOUN
bionys-641	108	2	peroxidase	peroxidase	NOUN
bionys-641	108	3	4	4	NUM
bionys-641	108	4	(	(	PUNCT
bionys-641	108	5	gpx4	gpx4	PROPN
bionys-641	108	6	)	)	PUNCT
bionys-641	108	7	is	be	AUX
bionys-641	108	8	the	the	DET
bionys-641	108	9	key	key	ADJ
bionys-641	108	10	enzyme	enzyme	NOUN
bionys-641	108	11	governing	govern	VERB
bionys-641	108	12	protection	protection	NOUN
bionys-641	108	13	against	against	ADP
bionys-641	108	14	ferroptosis	ferroptosis	NOUN
bionys-641	108	15	.	.	PUNCT
bionys-641	109	1	it	it	PRON
bionys-641	109	2	utilizes	utilize	VERB
bionys-641	109	3	glutathione	glutathione	NOUN
bionys-641	109	4	(	(	PUNCT
bionys-641	109	5	gsh	gsh	PROPN
bionys-641	109	6	)	)	PUNCT
bionys-641	109	7	to	to	PART
bionys-641	109	8	prevent	prevent	VERB
bionys-641	109	9	the	the	DET
bionys-641	109	10	accumulation	accumulation	NOUN
bionys-641	109	11	of	of	ADP
bionys-641	109	12	lipid	lipid	NOUN
bionys-641	109	13	peroxides	peroxide	NOUN
bionys-641	109	14	,	,	PUNCT
bionys-641	109	15	thereby	thereby	ADV
bionys-641	109	16	interfering	interfere	VERB
bionys-641	109	17	with	with	ADP
bionys-641	109	18	the	the	DET
bionys-641	109	19	system	system	NOUN
bionys-641	109	20	xc⁻	xc⁻	PROPN
bionys-641	109	21	or	or	CCONJ
bionys-641	109	22	incapacitating	incapacitate	VERB
bionys-641	109	23	gpx4	gpx4	PROPN
bionys-641	109	24	,	,	PUNCT
bionys-641	109	25	which	which	PRON
bionys-641	109	26	leads	lead	VERB
bionys-641	109	27	to	to	ADP
bionys-641	109	28	unregulated	unregulated	ADJ
bionys-641	109	29	lipoperoxidation	lipoperoxidation	NOUN
bionys-641	109	30	and	and	CCONJ
bionys-641	109	31	cell	cell	NOUN
bionys-641	109	32	death	death	NOUN
bionys-641	109	33	(	(	PUNCT
bionys-641	109	34	stockwell	stockwell	PROPN
bionys-641	109	35	et	et	PROPN
bionys-641	109	36	al	al	PROPN
bionys-641	109	37	.	.	PROPN
bionys-641	109	38	,	,	PUNCT
bionys-641	109	39	2020	2020	NUM
bionys-641	109	40	)	)	PUNCT
bionys-641	109	41	.	.	PUNCT
bionys-641	110	1	it	it	PRON
bionys-641	110	2	is	be	AUX
bionys-641	110	3	reliant	reliant	ADJ
bionys-641	110	4	substantially	substantially	ADV
bionys-641	110	5	on	on	ADP
bionys-641	110	6	the	the	DET
bionys-641	110	7	availability	availability	NOUN
bionys-641	110	8	of	of	ADP
bionys-641	110	9	labile	labile	ADJ
bionys-641	110	10	iron	iron	NOUN
bionys-641	110	11	that	that	PRON
bionys-641	110	12	participates	participate	VERB
bionys-641	110	13	in	in	ADP
bionys-641	110	14	fenton	fenton	NOUN
bionys-641	110	15	reactions	reaction	NOUN
bionys-641	110	16	to	to	PART
bionys-641	110	17	generate	generate	VERB
bionys-641	110	18	reactive	reactive	ADJ
bionys-641	110	19	oxygen	oxygen	NOUN
bionys-641	110	20	species	specie	NOUN
bionys-641	110	21	(	(	PUNCT
bionys-641	110	22	ros	ros	PROPN
bionys-641	110	23	)	)	PUNCT
bionys-641	110	24	causing	cause	VERB
bionys-641	110	25	lipoperoxidation	lipoperoxidation	NOUN
bionys-641	110	26	(	(	PUNCT
bionys-641	110	27	xu	xu	INTJ
bionys-641	110	28	et	et	PROPN
bionys-641	110	29	al	al	PROPN
bionys-641	110	30	.	.	PROPN
bionys-641	110	31	,	,	PUNCT
bionys-641	110	32	2024	2024	NUM
bionys-641	110	33	)	)	PUNCT
bionys-641	110	34	.	.	PUNCT
bionys-641	111	1	pyroptosis	pyroptosis	NOUN
bionys-641	111	2	classical	classical	ADJ
bionys-641	111	3	apoptosis	apoptosis	NOUN
bionys-641	111	4	can	can	AUX
bionys-641	111	5	be	be	AUX
bionys-641	111	6	recognized	recognize	VERB
bionys-641	111	7	by	by	ADP
bionys-641	111	8	the	the	DET
bionys-641	111	9	partitioning	partitioning	NOUN
bionys-641	111	10	of	of	ADP
bionys-641	111	11	internal	internal	ADJ
bionys-641	111	12	materials	material	NOUN
bionys-641	111	13	inside	inside	ADP
bionys-641	111	14	the	the	DET
bionys-641	111	15	cell	cell	NOUN
bionys-641	111	16	and	and	CCONJ
bionys-641	111	17	the	the	DET
bionys-641	111	18	removal	removal	NOUN
bionys-641	111	19	of	of	ADP
bionys-641	111	20	cellular	cellular	ADJ
bionys-641	111	21	debris	debris	NOUN
bionys-641	111	22	without	without	ADP
bionys-641	111	23	causing	cause	VERB
bionys-641	111	24	collateral	collateral	ADJ
bionys-641	111	25	injury	injury	NOUN
bionys-641	111	26	to	to	ADP
bionys-641	111	27	adjacent	adjacent	ADJ
bionys-641	111	28	tissues	tissue	NOUN
bionys-641	111	29	(	(	PUNCT
bionys-641	111	30	fink	fink	PROPN
bionys-641	111	31	&	&	CCONJ
bionys-641	111	32	cookson	cookson	PROPN
bionys-641	111	33	,	,	PUNCT
bionys-641	111	34	2005	2005	NUM
bionys-641	111	35	)	)	PUNCT
bionys-641	111	36	.	.	PUNCT
bionys-641	112	1	zychlinsky	zychlinsky	PROPN
bionys-641	112	2	et	et	PROPN
bionys-641	112	3	al	al	PROPN
bionys-641	112	4	.	.	PROPN
bionys-641	113	1	(	(	PUNCT
bionys-641	113	2	1992	1992	NUM
bionys-641	113	3	)	)	PUNCT
bionys-641	113	4	discovered	discover	VERB
bionys-641	113	5	pyroptosis	pyroptosis	NOUN
bionys-641	113	6	for	for	ADP
bionys-641	113	7	the	the	DET
bionys-641	113	8	first	first	ADJ
bionys-641	113	9	time	time	NOUN
bionys-641	113	10	,	,	PUNCT
bionys-641	113	11	a	a	DET
bionys-641	113	12	type	type	NOUN
bionys-641	113	13	of	of	ADP
bionys-641	113	14	cell	cell	NOUN
bionys-641	113	15	death	death	NOUN
bionys-641	113	16	caused	cause	VERB
bionys-641	113	17	by	by	ADP
bionys-641	113	18	proinflammatory	proinflammatory	ADJ
bionys-641	113	19	impulses	impulse	NOUN
bionys-641	113	20	and	and	CCONJ
bionys-641	113	21	linked	link	VERB
bionys-641	113	22	to	to	ADP
bionys-641	113	23	an	an	DET
bionys-641	113	24	inflammatory	inflammatory	ADJ
bionys-641	113	25	process	process	NOUN
bionys-641	113	26	.	.	PUNCT
bionys-641	114	1	pyroptosis	pyroptosis	NOUN
bionys-641	114	2	was	be	AUX
bionys-641	114	3	first	first	ADV
bionys-641	114	4	detected	detect	VERB
bionys-641	114	5	as	as	ADP
bionys-641	114	6	a	a	DET
bionys-641	114	7	suicide	suicide	NOUN
bionys-641	114	8	mechanism	mechanism	NOUN
bionys-641	114	9	of	of	ADP
bionys-641	114	10	the	the	DET
bionys-641	114	11	gram	gram	NOUN
bionys-641	114	12	-	-	PUNCT
bionys-641	114	13	negative	negative	ADJ
bionys-641	114	14	bacterial	bacterial	ADJ
bionys-641	114	15	pathogen	pathogen	NOUN
bionys-641	114	16	shigella	shigella	PROPN
bionys-641	114	17	flexneri	flexneri	ADJ
bionys-641	114	18	-	-	PUNCT
bionys-641	114	19	infected	infect	VERB
bionys-641	114	20	macrophages	macrophage	NOUN
bionys-641	114	21	,	,	PUNCT
bionys-641	114	22	and	and	CCONJ
bionys-641	114	23	later	later	ADV
bionys-641	114	24	in	in	ADP
bionys-641	114	25	salmonella	salmonella	NOUN
bionys-641	114	26	-	-	PUNCT
bionys-641	114	27	infected	infect	VERB
bionys-641	114	28	cells	cell	NOUN
bionys-641	114	29	(	(	PUNCT
bionys-641	114	30	zychlinsky	zychlinsky	PROPN
bionys-641	114	31	et	et	PROPN
bionys-641	114	32	al	al	PROPN
bionys-641	114	33	.	.	PROPN
bionys-641	114	34	,	,	PUNCT
bionys-641	114	35	1992	1992	NUM
bionys-641	114	36	;	;	PUNCT
bionys-641	114	37	hilbi	hilbi	PROPN
bionys-641	114	38	et	et	PROPN
bionys-641	114	39	al	al	PROPN
bionys-641	114	40	.	.	PROPN
bionys-641	114	41	,	,	PUNCT
bionys-641	114	42	1998	1998	NUM
bionys-641	114	43	;	;	PUNCT
bionys-641	114	44	hersh	hersh	PROPN
bionys-641	114	45	et	et	PROPN
bionys-641	114	46	al	al	PROPN
bionys-641	114	47	.	.	PROPN
bionys-641	114	48	,	,	PUNCT
bionys-641	114	49	1999	1999	NUM
bionys-641	114	50	)	)	PUNCT
bionys-641	114	51	.	.	PUNCT
bionys-641	115	1	this	this	PRON
bionys-641	115	2	is	be	AUX
bionys-641	115	3	a	a	DET
bionys-641	115	4	highly	highly	ADV
bionys-641	115	5	inflammatory	inflammatory	ADJ
bionys-641	115	6	form	form	NOUN
bionys-641	115	7	of	of	ADP
bionys-641	115	8	rcd	rcd	PROPN
bionys-641	115	9	mediated	mediate	VERB
bionys-641	115	10	by	by	ADP
bionys-641	115	11	the	the	DET
bionys-641	115	12	gasdermin	gasdermin	ADJ
bionys-641	115	13	family	family	NOUN
bionys-641	115	14	of	of	ADP
bionys-641	115	15	poreforming	poreforming	NOUN
bionys-641	115	16	proteins	protein	NOUN
bionys-641	115	17	,	,	PUNCT
bionys-641	115	18	considered	consider	VERB
bionys-641	115	19	as	as	ADP
bionys-641	115	20	a	a	DET
bionys-641	115	21	key	key	ADJ
bionys-641	115	22	component	component	NOUN
bionys-641	115	23	of	of	ADP
bionys-641	115	24	the	the	DET
bionys-641	115	25	innate	innate	ADJ
bionys-641	115	26	immune	immune	ADJ
bionys-641	115	27	response	response	NOUN
bionys-641	115	28	to	to	PART
bionys-641	115	29	pathogen	pathogen	VERB
bionys-641	115	30	infection	infection	NOUN
bionys-641	115	31	and	and	CCONJ
bionys-641	115	32	other	other	ADJ
bionys-641	115	33	danger	danger	NOUN
bionys-641	115	34	signals	signal	NOUN
bionys-641	115	35	(	(	PUNCT
bionys-641	115	36	he	he	PRON
bionys-641	115	37	et	et	PROPN
bionys-641	115	38	al	al	PROPN
bionys-641	115	39	.	.	PROPN
bionys-641	115	40	,	,	PUNCT
bionys-641	115	41	2015	2015	NUM
bionys-641	115	42	)	)	PUNCT
bionys-641	115	43	.	.	PUNCT
bionys-641	116	1	pyroptosis	pyroptosis	NOUN
bionys-641	116	2	is	be	AUX
bionys-641	116	3	primarily	primarily	ADV
bionys-641	116	4	instigated	instigate	VERB
bionys-641	116	5	by	by	ADP
bionys-641	116	6	the	the	DET
bionys-641	116	7	activation	activation	NOUN
bionys-641	116	8	of	of	ADP
bionys-641	116	9	inflammasomes	inflammasome	NOUN
bionys-641	116	10	the	the	DET
bionys-641	116	11	intracellular	intracellular	ADJ
bionys-641	116	12	multimeric	multimeric	ADJ
bionys-641	116	13	sensing	sense	VERB
bionys-641	116	14	complexes	complex	NOUN
bionys-641	116	15	of	of	ADP
bionys-641	116	16	pathogen	pathogen	NOUN
bionys-641	116	17	-	-	PUNCT
bionys-641	116	18	associated	associate	VERB
bionys-641	116	19	molecular	molecular	ADJ
bionys-641	116	20	patterns	pattern	NOUN
bionys-641	116	21	(	(	PUNCT
bionys-641	116	22	pamps	pamp	NOUN
bionys-641	116	23	)	)	PUNCT
bionys-641	116	24	or	or	CCONJ
bionys-641	116	25	damage	damage	NOUN
bionys-641	116	26	-	-	PUNCT
bionys-641	116	27	associated	associate	VERB
bionys-641	116	28	molecular	molecular	ADJ
bionys-641	116	29	patterns	pattern	NOUN
bionys-641	116	30	damps	damp	VERB
bionys-641	116	31	(	(	PUNCT
bionys-641	116	32	zhang	zhang	X
bionys-641	116	33	et	et	PROPN
bionys-641	116	34	al	al	PROPN
bionys-641	116	35	.	.	PROPN
bionys-641	116	36	,	,	PUNCT
bionys-641	116	37	2021	2021	NUM
bionys-641	116	38	)	)	PUNCT
bionys-641	116	39	.	.	PUNCT
bionys-641	117	1	activated	activate	VERB
bionys-641	117	2	inflammasomes	inflammasome	NOUN
bionys-641	117	3	(	(	PUNCT
bionys-641	117	4	particularly	particularly	ADV
bionys-641	117	5	the	the	DET
bionys-641	117	6	nlrp3	nlrp3	NOUN
bionys-641	117	7	inflammasome	inflammasome	NOUN
bionys-641	117	8	)	)	PUNCT
bionys-641	117	9	result	result	VERB
bionys-641	117	10	in	in	ADP
bionys-641	117	11	cleavage	cleavage	NOUN
bionys-641	117	12	and	and	CCONJ
bionys-641	117	13	activation	activation	NOUN
bionys-641	117	14	of	of	ADP
bionys-641	117	15	inflammatory	inflammatory	ADJ
bionys-641	117	16	caspases	caspase	NOUN
bionys-641	117	17	like	like	ADP
bionys-641	117	18	caspase-1	caspase-1	PROPN
bionys-641	117	19	within	within	ADP
bionys-641	117	20	caspase	caspase	PROPN
bionys-641	117	21	8	8	NUM
bionys-641	117	22	and	and	CCONJ
bionys-641	117	23	triggers	trigger	VERB
bionys-641	117	24	apoptosis	apoptosis	NOUN
bionys-641	117	25	(	(	PUNCT
bionys-641	117	26	kober	kober	PROPN
bionys-641	117	27	et	et	PROPN
bionys-641	117	28	al	al	PROPN
bionys-641	117	29	.	.	PROPN
bionys-641	117	30	,	,	PUNCT
bionys-641	117	31	2011	2011	NUM
bionys-641	117	32	)	)	PUNCT
bionys-641	117	33	.	.	PUNCT
bionys-641	118	1	necroptosis	necroptosis	NOUN
bionys-641	118	2	in	in	ADP
bionys-641	118	3	2005	2005	NUM
bionys-641	118	4	,	,	PUNCT
bionys-641	118	5	a	a	DET
bionys-641	118	6	new	new	ADJ
bionys-641	118	7	cell	cell	NOUN
bionys-641	118	8	death	death	NOUN
bionys-641	118	9	variant	variant	NOUN
bionys-641	118	10	was	be	AUX
bionys-641	118	11	discovered	discover	VERB
bionys-641	118	12	which	which	PRON
bionys-641	118	13	resembled	resemble	VERB
bionys-641	118	14	necrosis	necrosis	NOUN
bionys-641	118	15	but	but	CCONJ
bionys-641	118	16	had	have	VERB
bionys-641	118	17	distinct	distinct	ADJ
bionys-641	118	18	characteristics	characteristic	NOUN
bionys-641	118	19	.	.	PUNCT
bionys-641	119	1	it	it	PRON
bionys-641	119	2	is	be	AUX
bionys-641	119	3	an	an	DET
bionys-641	119	4	alternate	alternate	ADJ
bionys-641	119	5	form	form	NOUN
bionys-641	119	6	of	of	ADP
bionys-641	119	7	necrosis	necrosis	NOUN
bionys-641	119	8	;	;	PUNCT
bionys-641	119	9	however	however	ADV
bionys-641	119	10	,	,	PUNCT
bionys-641	119	11	in	in	ADP
bionys-641	119	12	this	this	DET
bionys-641	119	13	circumstance	circumstance	NOUN
bionys-641	119	14	,	,	PUNCT
bionys-641	119	15	cells	cell	NOUN
bionys-641	119	16	may	may	AUX
bionys-641	119	17	undergo	undergo	VERB
bionys-641	119	18	necrosis	necrosis	NOUN
bionys-641	119	19	in	in	ADP
bionys-641	119	20	a	a	DET
bionys-641	119	21	controlled	control	VERB
bionys-641	119	22	manner	manner	NOUN
bionys-641	119	23	(	(	PUNCT
bionys-641	119	24	conrad	conrad	PROPN
bionys-641	119	25	et	et	PROPN
bionys-641	119	26	al	al	PROPN
bionys-641	119	27	.	.	PROPN
bionys-641	119	28	,	,	PUNCT
bionys-641	119	29	2016	2016	NUM
bionys-641	119	30	)	)	PUNCT
bionys-641	119	31	,	,	PUNCT
bionys-641	119	32	implying	imply	VERB
bionys-641	119	33	that	that	SCONJ
bionys-641	119	34	apoptosis	apoptosis	NOUN
bionys-641	119	35	is	be	AUX
bionys-641	119	36	not	not	PART
bionys-641	119	37	necessarily	necessarily	ADV
bionys-641	119	38	the	the	DET
bionys-641	119	39	favored	favor	VERB
bionys-641	119	40	mode	mode	NOUN
bionys-641	119	41	of	of	ADP
bionys-641	119	42	cell	cell	NOUN
bionys-641	119	43	death	death	NOUN
bionys-641	119	44	.	.	PUNCT
bionys-641	120	1	this	this	DET
bionys-641	120	2	sort	sort	NOUN
bionys-641	120	3	of	of	ADP
bionys-641	120	4	cell	cell	NOUN
bionys-641	120	5	death	death	NOUN
bionys-641	120	6	is	be	AUX
bionys-641	120	7	known	know	VERB
bionys-641	120	8	as	as	ADP
bionys-641	120	9	necroptosis	necroptosis	NOUN
bionys-641	120	10	(	(	PUNCT
bionys-641	120	11	degterev	degterev	X
bionys-641	120	12	et	et	PROPN
bionys-641	120	13	al	al	PROPN
bionys-641	120	14	.	.	PROPN
bionys-641	120	15	,	,	PUNCT
bionys-641	120	16	2005	2005	NUM
bionys-641	120	17	)	)	PUNCT
bionys-641	120	18	.	.	PUNCT
bionys-641	121	1	necroptosis	necroptosis	NOUN
bionys-641	121	2	is	be	AUX
bionys-641	121	3	a	a	DET
bionys-641	121	4	pro	pro	ADJ
bionys-641	121	5	-	-	ADJ
bionys-641	121	6	inflammatory	inflammatory	ADJ
bionys-641	121	7	,	,	PUNCT
bionys-641	121	8	lytic	lytic	ADJ
bionys-641	121	9	rcd	rcd	PROPN
bionys-641	121	10	type	type	NOUN
bionys-641	121	11	that	that	PRON
bionys-641	121	12	serves	serve	VERB
bionys-641	121	13	as	as	ADP
bionys-641	121	14	an	an	DET
bionys-641	121	15	established	establish	VERB
bionys-641	121	16	viral	viral	ADJ
bionys-641	121	17	defense	defense	NOUN
bionys-641	121	18	process	process	NOUN
bionys-641	121	19	that	that	PRON
bionys-641	121	20	allows	allow	VERB
bionys-641	121	21	cells	cell	NOUN
bionys-641	121	22	to	to	PART
bionys-641	121	23	commit	commit	VERB
bionys-641	121	24	„	„	PUNCT
bionys-641	121	25	cellular	cellular	ADJ
bionys-641	121	26	suicide	suicide	NOUN
bionys-641	121	27	”	"	PUNCT
bionys-641	121	28	in	in	ADP
bionys-641	121	29	a	a	DET
bionys-641	121	30	caspase	caspase	NOUN
bionys-641	121	31	-	-	PUNCT
bionys-641	121	32	independent	independent	ADJ
bionys-641	121	33	fashion	fashion	NOUN
bionys-641	121	34	in	in	ADP
bionys-641	121	35	the	the	DET
bionys-641	121	36	presence	presence	NOUN
bionys-641	121	37	of	of	ADP
bionys-641	121	38	viral	viral	ADJ
bionys-641	121	39	caspase	caspase	NOUN
bionys-641	121	40	inhibitors	inhibitor	NOUN
bionys-641	121	41	(	(	PUNCT
bionys-641	121	42	associated	associate	VERB
bionys-641	121	43	with	with	ADP
bionys-641	121	44	apoptosis	apoptosis	NOUN
bionys-641	121	45	blockage	blockage	NOUN
bionys-641	121	46	)	)	PUNCT
bionys-641	121	47	to	to	PART
bionys-641	121	48	limit	limit	VERB
bionys-641	121	49	virus	virus	NOUN
bionys-641	121	50	reproduction	reproduction	NOUN
bionys-641	121	51	(	(	PUNCT
bionys-641	121	52	orzalli	orzalli	PROPN
bionys-641	121	53	&	&	CCONJ
bionys-641	121	54	kagan	kagan	PROPN
bionys-641	121	55	,	,	PUNCT
bionys-641	121	56	2017	2017	NUM
bionys-641	121	57	)	)	PUNCT
bionys-641	121	58	.	.	PUNCT
bionys-641	122	1	furthermore	furthermore	ADV
bionys-641	122	2	,	,	PUNCT
bionys-641	122	3	necroptosis	necroptosis	NOUN
bionys-641	122	4	has	have	AUX
bionys-641	122	5	been	be	AUX
bionys-641	122	6	linked	link	VERB
bionys-641	122	7	to	to	ADP
bionys-641	122	8	inflammatory	inflammatory	ADJ
bionys-641	122	9	disorders	disorder	NOUN
bionys-641	122	10	occurring	occur	VERB
bionys-641	122	11	in	in	ADP
bionys-641	122	12	several	several	ADJ
bionys-641	122	13	organ	organ	NOUN
bionys-641	122	14	systems	system	NOUN
bionys-641	122	15	,	,	PUNCT
bionys-641	122	16	including	include	VERB
bionys-641	122	17	the	the	DET
bionys-641	122	18	pulmonary	pulmonary	ADJ
bionys-641	122	19	,	,	PUNCT
bionys-641	122	20	gastrointestinal	gastrointestinal	ADJ
bionys-641	122	21	,	,	PUNCT
bionys-641	122	22	neurological	neurological	ADJ
bionys-641	122	23	,	,	PUNCT
bionys-641	122	24	and	and	CCONJ
bionys-641	122	25	cardiovascular	cardiovascular	ADJ
bionys-641	122	26	systems	system	NOUN
bionys-641	122	27	(	(	PUNCT
bionys-641	122	28	khoury	khoury	PROPN
bionys-641	122	29	et	et	PROPN
bionys-641	122	30	al	al	PROPN
bionys-641	122	31	.	.	PROPN
bionys-641	122	32	,	,	PUNCT
bionys-641	122	33	2020	2020	NUM
bionys-641	122	34	)	)	PUNCT
bionys-641	122	35	.	.	PUNCT
bionys-641	123	1	in	in	ADP
bionys-641	123	2	an	an	DET
bionys-641	123	3	environment	environment	NOUN
bionys-641	123	4	-	-	PUNCT
bionys-641	123	5	deprived	deprive	VERB
bionys-641	123	6	scenario	scenario	NOUN
bionys-641	123	7	,	,	PUNCT
bionys-641	123	8	necroptosis	necroptosis	NOUN
bionys-641	123	9	is	be	AUX
bionys-641	123	10	modulated	modulate	VERB
bionys-641	123	11	by	by	ADP
bionys-641	123	12	the	the	DET
bionys-641	123	13	receptor	receptor	NOUN
bionys-641	123	14	-	-	PUNCT
bionys-641	123	15	interacting	interact	VERB
bionys-641	123	16	proteins	protein	NOUN
bionys-641	123	17	1	1	NUM
bionys-641	123	18	and	and	CCONJ
bionys-641	123	19	3	3	NUM
bionys-641	123	20	(	(	PUNCT
bionys-641	123	21	rip1	rip1	PROPN
bionys-641	123	22	and	and	CCONJ
bionys-641	123	23	rip3	rip3	PROPN
bionys-641	123	24	)	)	PUNCT
bionys-641	123	25	(	(	PUNCT
bionys-641	123	26	moriwaki	moriwaki	NOUN
bionys-641	123	27	et	et	PROPN
bionys-641	123	28	al	al	PROPN
bionys-641	123	29	.	.	PROPN
bionys-641	123	30	,	,	PUNCT
bionys-641	123	31	2015	2015	NUM
bionys-641	123	32	)	)	PUNCT
bionys-641	123	33	.	.	PUNCT
bionys-641	124	1	the	the	DET
bionys-641	124	2	dr	dr	PROPN
bionys-641	124	3	is	be	AUX
bionys-641	124	4	the	the	DET
bionys-641	124	5	most	most	ADV
bionys-641	124	6	recognized	recognize	VERB
bionys-641	124	7	activation	activation	NOUN
bionys-641	124	8	mechanism	mechanism	NOUN
bionys-641	124	9	for	for	ADP
bionys-641	124	10	necroptosis	necroptosis	NOUN
bionys-641	124	11	,	,	PUNCT
bionys-641	124	12	which	which	PRON
bionys-641	124	13	is	be	AUX
bionys-641	124	14	most	most	ADV
bionys-641	124	15	typically	typically	ADV
bionys-641	124	16	driven	drive	VERB
bionys-641	124	17	by	by	ADP
bionys-641	124	18	tnfr1	tnfr1	PROPN
bionys-641	124	19	.	.	PUNCT
bionys-641	125	1	simultaneously	simultaneously	ADV
bionys-641	125	2	,	,	PUNCT
bionys-641	125	3	other	other	ADJ
bionys-641	125	4	factors	factor	NOUN
bionys-641	125	5	,	,	PUNCT
bionys-641	125	6	including	include	VERB
bionys-641	125	7	tumor	tumor	NOUN
bionys-641	125	8	necrosis	necrosis	NOUN
bionys-641	125	9	factor	factor	NOUN
bionys-641	125	10	receptor	receptor	NOUN
bionys-641	125	11	-	-	PUNCT
bionys-641	125	12	related	relate	VERB
bionys-641	125	13	apoptosisinducing	apoptosisinducing	NOUN
bionys-641	125	14	ligand	ligand	NOUN
bionys-641	125	15	(	(	PUNCT
bionys-641	125	16	trail	trail	NOUN
bionys-641	125	17	)	)	PUNCT
bionys-641	125	18	and	and	CCONJ
bionys-641	125	19	the	the	DET
bionys-641	125	20	fas	fas	PROPN
bionys-641	125	21	receptor	receptor	NOUN
bionys-641	125	22	,	,	PUNCT
bionys-641	125	23	may	may	AUX
bionys-641	125	24	act	act	VERB
bionys-641	125	25	to	to	ADP
bionys-641	125	26	trigger	trigger	NOUN
bionys-641	125	27	necroptosis	necroptosis	NOUN
bionys-641	125	28	(	(	PUNCT
bionys-641	125	29	kim	kim	PROPN
bionys-641	125	30	&	&	CCONJ
bionys-641	125	31	li	li	PROPN
bionys-641	125	32	,	,	PUNCT
bionys-641	125	33	2013	2013	NUM
bionys-641	125	34	)	)	PUNCT
bionys-641	125	35	.	.	PUNCT
bionys-641	126	1	ligand	ligand	ADJ
bionys-641	126	2	attachment	attachment	NOUN
bionys-641	126	3	to	to	ADP
bionys-641	126	4	tnfr1	tnfr1	NOUN
bionys-641	126	5	can	can	AUX
bionys-641	126	6	initiate	initiate	VERB
bionys-641	126	7	prosurvival	prosurvival	NOUN
bionys-641	126	8	complex	complex	NOUN
bionys-641	126	9	i	i	NOUN
bionys-641	126	10	activation	activation	NOUN
bionys-641	126	11	,	,	PUNCT
bionys-641	126	12	including	include	VERB
bionys-641	126	13	tnfrassociated	tnfrassociate	VERB
bionys-641	126	14	death	death	NOUN
bionys-641	126	15	domain	domain	NOUN
bionys-641	126	16	(	(	PUNCT
bionys-641	126	17	tradd	tradd	NOUN
bionys-641	126	18	)	)	PUNCT
bionys-641	126	19	,	,	PUNCT
bionys-641	126	20	rip1	rip1	PROPN
bionys-641	126	21	,	,	PUNCT
bionys-641	126	22	and	and	CCONJ
bionys-641	126	23	some	some	DET
bionys-641	126	24	e3	e3	VERB
bionys-641	126	25	ubiquitin	ubiquitin	ADJ
bionys-641	126	26	ligases	ligase	NOUN
bionys-641	126	27	.	.	PUNCT
bionys-641	127	1	rip1	rip1	PROPN
bionys-641	127	2	is	be	AUX
bionys-641	127	3	polyubiquitinated	polyubiquitinate	VERB
bionys-641	127	4	within	within	ADP
bionys-641	127	5	the	the	DET
bionys-641	127	6	complex	complex	NOUN
bionys-641	127	7	i	i	PRON
bionys-641	127	8	;	;	PUNCT
bionys-641	127	9	meanwhile	meanwhile	ADV
bionys-641	127	10	,	,	PUNCT
bionys-641	127	11	deubiquitination	deubiquitination	NOUN
bionys-641	127	12	of	of	ADP
bionys-641	127	13	rip1	rip1	PROPN
bionys-641	127	14	causes	cause	VERB
bionys-641	127	15	the	the	DET
bionys-641	127	16	formation	formation	NOUN
bionys-641	127	17	of	of	ADP
bionys-641	127	18	complex	complex	ADJ
bionys-641	127	19	iia	iia	NOUN
bionys-641	127	20	or	or	CCONJ
bionys-641	127	21	iib	iib	PROPN
bionys-641	127	22	.	.	PUNCT
bionys-641	128	1	complex	complex	ADJ
bionys-641	128	2	iia	iia	NOUN
bionys-641	128	3	drives	drive	NOUN
bionys-641	128	4	caspase	caspase	NOUN
bionys-641	128	5	8	8	NUM
bionys-641	128	6	activation	activation	NOUN
bionys-641	128	7	and	and	CCONJ
bionys-641	128	8	induces	induce	NOUN
bionys-641	128	9	apoptosis	apoptosis	NOUN
bionys-641	128	10	,	,	PUNCT
bionys-641	128	11	while	while	SCONJ
bionys-641	128	12	its	its	PRON
bionys-641	128	13	inhibition	inhibition	NOUN
bionys-641	128	14	results	result	NOUN
bionys-641	128	15	in	in	ADP
bionys-641	128	16	the	the	DET
bionys-641	128	17	formation	formation	NOUN
bionys-641	128	18	of	of	ADP
bionys-641	128	19	complex	complex	ADJ
bionys-641	128	20	iib	iib	NOUN
bionys-641	128	21	,	,	PUNCT
bionys-641	128	22	which	which	PRON
bionys-641	128	23	stimulates	stimulate	VERB
bionys-641	128	24	necroptosis	necroptosis	NOUN
bionys-641	128	25	(	(	PUNCT
bionys-641	128	26	chen	chen	PROPN
bionys-641	128	27	et	et	PROPN
bionys-641	128	28	al	al	PROPN
bionys-641	128	29	.	.	PROPN
bionys-641	128	30	,	,	PUNCT
bionys-641	128	31	2019	2019	NUM
bionys-641	128	32	)	)	PUNCT
bionys-641	128	33	.	.	PUNCT
bionys-641	129	1	to	to	PART
bionys-641	129	2	initiate	initiate	VERB
bionys-641	129	3	necroptosis	necroptosis	NOUN
bionys-641	129	4	,	,	PUNCT
bionys-641	129	5	complex	complex	ADJ
bionys-641	129	6	iib	iib	NOUN
bionys-641	129	7	requires	require	VERB
bionys-641	129	8	rip1	rip1	PROPN
bionys-641	129	9	to	to	PART
bionys-641	129	10	partner	partner	VERB
bionys-641	129	11	with	with	ADP
bionys-641	129	12	rip3	rip3	NOUN
bionys-641	129	13	and	and	CCONJ
bionys-641	129	14	cause	cause	VERB
bionys-641	129	15	autoand	autoand	NOUN
bionys-641	129	16	transphosphorylation	transphosphorylation	NOUN
bionys-641	129	17	,	,	PUNCT
bionys-641	129	18	which	which	PRON
bionys-641	129	19	leads	lead	VERB
bionys-641	129	20	to	to	ADP
bionys-641	129	21	the	the	DET
bionys-641	129	22	oligomerization	oligomerization	NOUN
bionys-641	129	23	of	of	ADP
bionys-641	129	24	phosphorylated	phosphorylate	VERB
bionys-641	129	25	rip3	rip3	NOUN
bionys-641	129	26	.	.	PUNCT
bionys-641	130	1	this	this	PRON
bionys-641	130	2	results	result	VERB
bionys-641	130	3	in	in	ADP
bionys-641	130	4	the	the	DET
bionys-641	130	5	formation	formation	NOUN
bionys-641	130	6	of	of	ADP
bionys-641	130	7	necrosomes	necrosome	NOUN
bionys-641	130	8	,	,	PUNCT
bionys-641	130	9	which	which	PRON
bionys-641	130	10	are	be	AUX
bionys-641	130	11	amyloid	amyloid	NOUN
bionys-641	130	12	-	-	PUNCT
bionys-641	130	13	like	like	ADJ
bionys-641	130	14	multiprotein	multiprotein	ADJ
bionys-641	130	15	complexes	complex	NOUN
bionys-641	130	16	that	that	PRON
bionys-641	130	17	distinguish	distinguish	VERB
bionys-641	130	18	them	they	PRON
bionys-641	130	19	from	from	ADP
bionys-641	130	20	uncontrolled	uncontrolled	ADJ
bionys-641	130	21	necrosis	necrosis	NOUN
bionys-641	130	22	.	.	PUNCT
bionys-641	131	1	morphologically	morphologically	ADV
bionys-641	131	2	,	,	PUNCT
bionys-641	131	3	necroptosis	necroptosis	NOUN
bionys-641	131	4	mimics	mimic	VERB
bionys-641	131	5	unregulated	unregulated	ADJ
bionys-641	131	6	necrosis	necrosis	NOUN
bionys-641	131	7	,	,	PUNCT
bionys-641	131	8	marked	mark	VERB
bionys-641	131	9	by	by	ADP
bionys-641	131	10	oncosis	oncosis	NOUN
bionys-641	131	11	,	,	PUNCT
bionys-641	131	12	the	the	DET
bionys-641	131	13	eventual	eventual	ADJ
bionys-641	131	14	burst	burst	NOUN
bionys-641	131	15	of	of	ADP
bionys-641	131	16	the	the	DET
bionys-641	131	17	plasma	plasma	NOUN
bionys-641	131	18	membrane	membrane	NOUN
bionys-641	131	19	,	,	PUNCT
bionys-641	131	20	and	and	CCONJ
bionys-641	131	21	the	the	DET
bionys-641	131	22	release	release	NOUN
bionys-641	131	23	of	of	ADP
bionys-641	131	24	pro	pro	ADJ
bionys-641	131	25	-	-	ADJ
bionys-641	131	26	inflammatory	inflammatory	ADJ
bionys-641	131	27	intracellular	intracellular	ADJ
bionys-641	131	28	components	component	NOUN
bionys-641	131	29	.	.	PUNCT
bionys-641	132	1	mixed	mixed	ADJ
bionys-641	132	2	lineage	lineage	NOUN
bionys-641	132	3	kinase	kinase	NOUN
bionys-641	132	4	domain	domain	NOUN
bionys-641	132	5	-	-	PUNCT
bionys-641	132	6	like	like	ADJ
bionys-641	132	7	pseudokinase	pseudokinase	NOUN
bionys-641	132	8	(	(	PUNCT
bionys-641	132	9	mlkl	mlkl	PROPN
bionys-641	132	10	)	)	PUNCT
bionys-641	132	11	,	,	PUNCT
bionys-641	132	12	in	in	ADP
bionys-641	132	13	addition	addition	NOUN
bionys-641	132	14	to	to	ADP
bionys-641	132	15	rip1	rip1	PROPN
bionys-641	132	16	and	and	CCONJ
bionys-641	132	17	rip3	rip3	PROPN
bionys-641	132	18	,	,	PUNCT
bionys-641	132	19	has	have	VERB
bionys-641	132	20	a	a	DET
bionys-641	132	21	role	role	NOUN
bionys-641	132	22	in	in	ADP
bionys-641	132	23	necroptosis	necroptosis	NOUN
bionys-641	132	24	(	(	PUNCT
bionys-641	132	25	cho	cho	NOUN
bionys-641	132	26	et	et	PROPN
bionys-641	132	27	al	al	PROPN
bionys-641	132	28	.	.	PROPN
bionys-641	132	29	,	,	PUNCT
bionys-641	132	30	2009	2009	NUM
bionys-641	132	31	;	;	PUNCT
bionys-641	132	32	berghe	berghe	NOUN
bionys-641	132	33	et	et	PROPN
bionys-641	132	34	al	al	PROPN
bionys-641	132	35	.	.	PROPN
bionys-641	132	36	,	,	PUNCT
bionys-641	132	37	2014	2014	NUM
bionys-641	132	38	)	)	PUNCT
bionys-641	132	39	.	.	PUNCT
bionys-641	133	1	rip3	rip3	PROPN
bionys-641	133	2	recruits	recruit	VERB
bionys-641	133	3	mlkl	mlkl	VERB
bionys-641	133	4	and	and	CCONJ
bionys-641	133	5	phosphorylates	phosphorylate	VERB
bionys-641	133	6	it	it	PRON
bionys-641	133	7	at	at	ADP
bionys-641	133	8	threonine	threonine	NOUN
bionys-641	133	9	357	357	NUM
bionys-641	133	10	and	and	CCONJ
bionys-641	133	11	serine	serine	VERB
bionys-641	133	12	358	358	NUM
bionys-641	133	13	.	.	PUNCT
bionys-641	134	1	biologica	biologica	PROPN
bionys-641	134	2	nyssana	nyssana	PROPN
bionys-641	134	3	●	●	PUNCT
bionys-641	134	4	16	16	NUM
bionys-641	134	5	(	(	PUNCT
bionys-641	134	6	2	2	NUM
bionys-641	134	7	)	)	PUNCT
bionys-641	134	8	december	december	PROPN
bionys-641	134	9	2025	2025	NUM
bionys-641	134	10	:	:	PUNCT
bionys-641	134	11	liana	liana	NOUN
bionys-641	134	12	et	et	PROPN
bionys-641	134	13	al	al	PROPN
bionys-641	134	14	.	.	PUNCT
bionys-641	135	1	●	●	PUNCT
bionys-641	135	2	cell	cell	NOUN
bionys-641	135	3	deaths	death	NOUN
bionys-641	135	4	and	and	CCONJ
bionys-641	135	5	their	their	PRON
bionys-641	135	6	associated	associate	VERB
bionys-641	135	7	mechanisms	mechanism	NOUN
bionys-641	135	8	the	the	DET
bionys-641	135	9	canonical	canonical	ADJ
bionys-641	135	10	pathway	pathway	NOUN
bionys-641	135	11	or	or	CCONJ
bionys-641	135	12	caspase-4/5	caspase-4/5	ADV
bionys-641	135	13	(	(	PUNCT
bionys-641	135	14	human	human	NOUN
bionys-641	135	15	)	)	PUNCT
bionys-641	135	16	and	and	CCONJ
bionys-641	135	17	caspase-11	caspase-11	PROPN
bionys-641	135	18	(	(	PUNCT
bionys-641	135	19	mouse	mouse	NOUN
bionys-641	135	20	)	)	PUNCT
bionys-641	135	21	within	within	ADP
bionys-641	135	22	the	the	DET
bionys-641	135	23	non	non	ADJ
bionys-641	135	24	-	-	ADJ
bionys-641	135	25	canonical	canonical	ADJ
bionys-641	135	26	signaling	signal	VERB
bionys-641	135	27	pathway	pathway	NOUN
bionys-641	135	28	(	(	PUNCT
bionys-641	135	29	zhang	zhang	PROPN
bionys-641	135	30	et	et	PROPN
bionys-641	135	31	al	al	PROPN
bionys-641	135	32	.	.	PROPN
bionys-641	135	33	,	,	PUNCT
bionys-641	135	34	2024	2024	NUM
bionys-641	135	35	)	)	PUNCT
bionys-641	135	36	.	.	PUNCT
bionys-641	136	1	activated	activate	VERB
bionys-641	136	2	caspases	caspase	NOUN
bionys-641	136	3	(	(	PUNCT
bionys-641	136	4	for	for	ADP
bionys-641	136	5	example	example	NOUN
bionys-641	136	6	procaspase	procaspase	NOUN
bionys-641	136	7	1	1	NUM
bionys-641	136	8	to	to	ADP
bionys-641	136	9	caspase	caspase	PROPN
bionys-641	136	10	1	1	NUM
bionys-641	136	11	)	)	PUNCT
bionys-641	136	12	cleave	cleave	VERB
bionys-641	136	13	a	a	DET
bionys-641	136	14	gasdermin	gasdermin	ADJ
bionys-641	136	15	family	family	NOUN
bionys-641	136	16	protein	protein	NOUN
bionys-641	136	17	,	,	PUNCT
bionys-641	136	18	mostly	mostly	ADV
bionys-641	136	19	gasdermin	gasdermin	ADJ
bionys-641	136	20	d	d	PROPN
bionys-641	136	21	(	(	PUNCT
bionys-641	136	22	gsdmd	gsdmd	NOUN
bionys-641	136	23	)	)	PUNCT
bionys-641	136	24	,	,	PUNCT
bionys-641	136	25	into	into	ADP
bionys-641	136	26	an	an	DET
bionys-641	136	27	n	n	CCONJ
bionys-641	136	28	-	-	PUNCT
bionys-641	136	29	terminal	terminal	ADJ
bionys-641	136	30	poreforming	poreforming	NOUN
bionys-641	136	31	domain	domain	NOUN
bionys-641	136	32	and	and	CCONJ
bionys-641	136	33	a	a	DET
bionys-641	136	34	c	c	NOUN
bionys-641	136	35	-	-	PUNCT
bionys-641	136	36	terminal	terminal	ADJ
bionys-641	136	37	inhibitor	inhibitor	NOUN
bionys-641	136	38	domain	domain	NOUN
bionys-641	136	39	(	(	PUNCT
bionys-641	136	40	he	he	PRON
bionys-641	136	41	et	et	PROPN
bionys-641	136	42	al	al	PROPN
bionys-641	136	43	.	.	PROPN
bionys-641	136	44	,	,	PUNCT
bionys-641	136	45	2015	2015	NUM
bionys-641	136	46	)	)	PUNCT
bionys-641	136	47	.	.	PUNCT
bionys-641	137	1	there	there	PRON
bionys-641	137	2	is	be	VERB
bionys-641	137	3	also	also	ADV
bionys-641	137	4	a	a	DET
bionys-641	137	5	secretion	secretion	NOUN
bionys-641	137	6	of	of	ADP
bionys-641	137	7	the	the	DET
bionys-641	137	8	pro	pro	ADJ
bionys-641	137	9	-	-	ADJ
bionys-641	137	10	inflammatory	inflammatory	ADJ
bionys-641	137	11	cytokines	cytokine	NOUN
bionys-641	137	12	interleukin	interleukin	NOUN
bionys-641	137	13	1β	1β	NUM
bionys-641	137	14	(	(	PUNCT
bionys-641	137	15	il-1β	il-1β	PROPN
bionys-641	137	16	)	)	PUNCT
bionys-641	137	17	and	and	CCONJ
bionys-641	137	18	il-18	il-18	ADP
bionys-641	137	19	in	in	ADP
bionys-641	137	20	their	their	PRON
bionys-641	137	21	active	active	ADJ
bionys-641	137	22	forms	form	NOUN
bionys-641	137	23	,	,	PUNCT
bionys-641	137	24	causing	cause	VERB
bionys-641	137	25	cell	cell	NOUN
bionys-641	137	26	death	death	NOUN
bionys-641	137	27	and	and	CCONJ
bionys-641	137	28	the	the	DET
bionys-641	137	29	release	release	NOUN
bionys-641	137	30	of	of	ADP
bionys-641	137	31	inflammatory	inflammatory	ADJ
bionys-641	137	32	cytokines	cytokine	NOUN
bionys-641	137	33	into	into	ADP
bionys-641	137	34	the	the	DET
bionys-641	137	35	surrounding	surround	VERB
bionys-641	137	36	milieu	milieu	NOUN
bionys-641	137	37	.	.	PUNCT
bionys-641	138	1	the	the	DET
bionys-641	138	2	n	n	CCONJ
bionys-641	138	3	-	-	PUNCT
bionys-641	138	4	terminal	terminal	ADJ
bionys-641	138	5	cleavage	cleavage	NOUN
bionys-641	138	6	product	product	NOUN
bionys-641	138	7	oligomerizes	oligomerize	NOUN
bionys-641	138	8	and	and	CCONJ
bionys-641	138	9	inserts	insert	NOUN
bionys-641	138	10	into	into	ADP
bionys-641	138	11	the	the	DET
bionys-641	138	12	cell	cell	NOUN
bionys-641	138	13	membrane	membrane	NOUN
bionys-641	138	14	and	and	CCONJ
bionys-641	138	15	forms	form	VERB
bionys-641	138	16	small	small	ADJ
bionys-641	138	17	pores	pore	NOUN
bionys-641	138	18	which	which	PRON
bionys-641	138	19	permit	permit	VERB
bionys-641	138	20	ions	ion	NOUN
bionys-641	138	21	to	to	PART
bionys-641	138	22	move	move	VERB
bionys-641	138	23	through	through	ADV
bionys-641	138	24	,	,	PUNCT
bionys-641	138	25	resulting	result	VERB
bionys-641	138	26	to	to	ADP
bionys-641	138	27	a	a	DET
bionys-641	138	28	discrepancy	discrepancy	NOUN
bionys-641	138	29	of	of	ADP
bionys-641	138	30	internal	internal	ADJ
bionys-641	138	31	and	and	CCONJ
bionys-641	138	32	extracellular	extracellular	ADJ
bionys-641	138	33	ionic	ionic	ADJ
bionys-641	138	34	slopes	slope	NOUN
bionys-641	138	35	(	(	PUNCT
bionys-641	138	36	after	after	ADP
bionys-641	138	37	potassium	potassium	NOUN
bionys-641	138	38	efflux	efflux	NOUN
bionys-641	138	39	)	)	PUNCT
bionys-641	138	40	;	;	PUNCT
bionys-641	138	41	water	water	NOUN
bionys-641	138	42	then	then	ADV
bionys-641	138	43	permeates	permeate	VERB
bionys-641	138	44	the	the	DET
bionys-641	138	45	cell	cell	NOUN
bionys-641	138	46	,	,	PUNCT
bionys-641	138	47	causing	cause	VERB
bionys-641	138	48	cell	cell	NOUN
bionys-641	138	49	expansion	expansion	NOUN
bionys-641	138	50	and	and	CCONJ
bionys-641	138	51	lysis	lysis	NOUN
bionys-641	138	52	,	,	PUNCT
bionys-641	138	53	in	in	ADP
bionys-641	138	54	addition	addition	NOUN
bionys-641	138	55	to	to	ADP
bionys-641	138	56	a	a	DET
bionys-641	138	57	collapse	collapse	NOUN
bionys-641	138	58	of	of	ADP
bionys-641	138	59	cell	cell	NOUN
bionys-641	138	60	membrane	membrane	NOUN
bionys-641	138	61	integrity	integrity	NOUN
bionys-641	138	62	(	(	PUNCT
bionys-641	138	63	wagatsuma	wagatsuma	PROPN
bionys-641	138	64	&	&	CCONJ
bionys-641	138	65	nakase	nakase	PROPN
bionys-641	138	66	,	,	PUNCT
bionys-641	138	67	2020	2020	NUM
bionys-641	138	68	)	)	PUNCT
bionys-641	138	69	.	.	PUNCT
bionys-641	139	1	autophagy	autophagy	ADJ
bionys-641	139	2	autophagy	autophagy	NOUN
bionys-641	139	3	is	be	AUX
bionys-641	139	4	when	when	SCONJ
bionys-641	139	5	cellular	cellular	ADJ
bionys-641	139	6	constituents	constituent	NOUN
bionys-641	139	7	,	,	PUNCT
bionys-641	139	8	such	such	ADJ
bionys-641	139	9	as	as	ADP
bionys-641	139	10	macroproteins	macroprotein	NOUN
bionys-641	139	11	or	or	CCONJ
bionys-641	139	12	organelles	organelle	NOUN
bionys-641	139	13	,	,	PUNCT
bionys-641	139	14	are	be	AUX
bionys-641	139	15	engulfed	engulf	VERB
bionys-641	139	16	in	in	ADP
bionys-641	139	17	the	the	DET
bionys-641	139	18	lysosome	lysosome	NOUN
bionys-641	139	19	(	(	PUNCT
bionys-641	139	20	intracellularly	intracellularly	ADV
bionys-641	139	21	)	)	PUNCT
bionys-641	139	22	to	to	PART
bionys-641	139	23	undergo	undergo	VERB
bionys-641	139	24	enzymatic	enzymatic	ADJ
bionys-641	139	25	breakdown	breakdown	NOUN
bionys-641	139	26	.	.	PUNCT
bionys-641	140	1	the	the	DET
bionys-641	140	2	lysosome	lysosome	NOUN
bionys-641	140	3	subsequently	subsequently	ADV
bionys-641	140	4	digests	digest	VERB
bionys-641	140	5	the	the	DET
bionys-641	140	6	substrate	substrate	NOUN
bionys-641	140	7	,	,	PUNCT
bionys-641	140	8	and	and	CCONJ
bionys-641	140	9	all	all	DET
bionys-641	140	10	elements	element	NOUN
bionys-641	140	11	that	that	PRON
bionys-641	140	12	can	can	AUX
bionys-641	140	13	not	not	PART
bionys-641	140	14	be	be	AUX
bionys-641	140	15	reconstituted	reconstitute	VERB
bionys-641	140	16	to	to	PART
bionys-641	140	17	form	form	VERB
bionys-641	140	18	novel	novel	ADJ
bionys-641	140	19	cell	cell	NOUN
bionys-641	140	20	components	component	NOUN
bionys-641	140	21	or	or	CCONJ
bionys-641	140	22	organelles	organelle	NOUN
bionys-641	140	23	are	be	AUX
bionys-641	140	24	further	far	ADV
bionys-641	140	25	broken	break	VERB
bionys-641	140	26	down	down	ADP
bionys-641	140	27	and	and	CCONJ
bionys-641	140	28	utilized	utilize	VERB
bionys-641	140	29	as	as	ADP
bionys-641	140	30	an	an	DET
bionys-641	140	31	energy	energy	NOUN
bionys-641	140	32	source	source	NOUN
bionys-641	140	33	(	(	PUNCT
bionys-641	140	34	ballabio	ballabio	PROPN
bionys-641	140	35	&	&	CCONJ
bionys-641	140	36	bonifacino	bonifacino	PROPN
bionys-641	140	37	,	,	PUNCT
bionys-641	140	38	2019	2019	NUM
bionys-641	140	39	)	)	PUNCT
bionys-641	140	40	.	.	PUNCT
bionys-641	141	1	autophagy	autophagy	NOUN
bionys-641	141	2	may	may	AUX
bionys-641	141	3	be	be	AUX
bionys-641	141	4	induced	induce	VERB
bionys-641	141	5	by	by	ADP
bionys-641	141	6	several	several	ADJ
bionys-641	141	7	stressors	stressor	NOUN
bionys-641	141	8	,	,	PUNCT
bionys-641	141	9	including	include	VERB
bionys-641	141	10	nutritional	nutritional	ADJ
bionys-641	141	11	shortages	shortage	NOUN
bionys-641	141	12	(	(	PUNCT
bionys-641	141	13	calorie	calorie	NOUN
bionys-641	141	14	deprivation	deprivation	NOUN
bionys-641	141	15	)	)	PUNCT
bionys-641	141	16	,	,	PUNCT
bionys-641	141	17	signals	signal	NOUN
bionys-641	141	18	occurring	occur	VERB
bionys-641	141	19	during	during	ADP
bionys-641	141	20	cellular	cellular	ADJ
bionys-641	141	21	differentiation	differentiation	NOUN
bionys-641	141	22	and	and	CCONJ
bionys-641	141	23	embryogenesis	embryogenesis	NOUN
bionys-641	141	24	,	,	PUNCT
bionys-641	141	25	and	and	CCONJ
bionys-641	141	26	compromised	compromise	VERB
bionys-641	141	27	organellar	organellar	ADJ
bionys-641	141	28	interfaces	interface	NOUN
bionys-641	141	29	.	.	PUNCT
bionys-641	142	1	autophagy	autophagy	PROPN
bionys-641	142	2	has	have	AUX
bionys-641	142	3	also	also	ADV
bionys-641	142	4	been	be	AUX
bionys-641	142	5	implicated	implicate	VERB
bionys-641	142	6	in	in	ADP
bionys-641	142	7	adaptive	adaptive	ADJ
bionys-641	142	8	and	and	CCONJ
bionys-641	142	9	innate	innate	ADJ
bionys-641	142	10	immune	immune	ADJ
bionys-641	142	11	reactions	reaction	NOUN
bionys-641	142	12	,	,	PUNCT
bionys-641	142	13	such	such	ADJ
bionys-641	142	14	as	as	ADP
bionys-641	142	15	defense	defense	NOUN
bionys-641	142	16	against	against	ADP
bionys-641	142	17	viral	viral	ADJ
bionys-641	142	18	infection	infection	NOUN
bionys-641	142	19	(	(	PUNCT
bionys-641	142	20	he	he	PRON
bionys-641	142	21	et	et	PROPN
bionys-641	142	22	al	al	PROPN
bionys-641	142	23	.	.	PROPN
bionys-641	142	24	,	,	PUNCT
bionys-641	142	25	2018	2018	NUM
bionys-641	142	26	)	)	PUNCT
bionys-641	142	27	.	.	PUNCT
bionys-641	143	1	following	follow	VERB
bionys-641	143	2	the	the	DET
bionys-641	143	3	breakdown	breakdown	NOUN
bionys-641	143	4	of	of	ADP
bionys-641	143	5	intracellular	intracellular	ADJ
bionys-641	143	6	pathogens	pathogen	NOUN
bionys-641	143	7	,	,	PUNCT
bionys-641	143	8	the	the	DET
bionys-641	143	9	antigen	antigen	NOUN
bionys-641	143	10	is	be	AUX
bionys-641	143	11	presented	present	VERB
bionys-641	143	12	to	to	ADP
bionys-641	143	13	the	the	DET
bionys-641	143	14	major	major	ADJ
bionys-641	143	15	histocompatibility	histocompatibility	NOUN
bionys-641	143	16	complex	complex	NOUN
bionys-641	143	17	(	(	PUNCT
bionys-641	143	18	mhc	mhc	PROPN
bionys-641	143	19	)	)	PUNCT
bionys-641	143	20	class	class	PROPN
bionys-641	143	21	ii	ii	PROPN
bionys-641	143	22	,	,	PUNCT
bionys-641	143	23	and	and	CCONJ
bionys-641	143	24	the	the	DET
bionys-641	143	25	nucleic	nucleic	ADJ
bionys-641	143	26	acid	acid	NOUN
bionys-641	143	27	from	from	ADP
bionys-641	143	28	the	the	DET
bionys-641	143	29	pathogenic	pathogenic	ADJ
bionys-641	143	30	organism	organism	NOUN
bionys-641	143	31	is	be	AUX
bionys-641	143	32	then	then	ADV
bionys-641	143	33	transferred	transfer	VERB
bionys-641	143	34	to	to	ADP
bionys-641	143	35	the	the	DET
bionys-641	143	36	toll	toll	NOUN
bionys-641	143	37	-	-	PUNCT
bionys-641	143	38	like	like	ADJ
bionys-641	143	39	receptor	receptor	NOUN
bionys-641	143	40	.	.	PUNCT
bionys-641	144	1	although	although	SCONJ
bionys-641	144	2	autophagy	autophagy	NOUN
bionys-641	144	3	is	be	AUX
bionys-641	144	4	commonly	commonly	ADV
bionys-641	144	5	employed	employ	VERB
bionys-641	144	6	in	in	ADP
bionys-641	144	7	recycling	recycle	VERB
bionys-641	144	8	cellular	cellular	ADJ
bionys-641	144	9	parts	part	NOUN
bionys-641	144	10	,	,	PUNCT
bionys-641	144	11	it	it	PRON
bionys-641	144	12	may	may	AUX
bionys-641	144	13	also	also	ADV
bionys-641	144	14	cause	cause	VERB
bionys-641	144	15	cell	cell	NOUN
bionys-641	144	16	demise	demise	NOUN
bionys-641	144	17	.	.	PUNCT
bionys-641	145	1	it	it	PRON
bionys-641	145	2	has	have	AUX
bionys-641	145	3	been	be	AUX
bionys-641	145	4	attributed	attribute	VERB
bionys-641	145	5	to	to	ADP
bionys-641	145	6	the	the	DET
bionys-641	145	7	clearance	clearance	NOUN
bionys-641	145	8	of	of	ADP
bionys-641	145	9	senescent	senescent	ADJ
bionys-641	145	10	cells	cell	NOUN
bionys-641	145	11	from	from	ADP
bionys-641	145	12	old	old	ADJ
bionys-641	145	13	tissues	tissue	NOUN
bionys-641	145	14	and	and	CCONJ
bionys-641	145	15	eradication	eradication	NOUN
bionys-641	145	16	of	of	ADP
bionys-641	145	17	neoplastic	neoplastic	ADJ
bionys-641	145	18	tumors	tumor	NOUN
bionys-641	145	19	.	.	PUNCT
bionys-641	146	1	disruption	disruption	NOUN
bionys-641	146	2	of	of	ADP
bionys-641	146	3	autophagy	autophagy	NOUN
bionys-641	146	4	may	may	AUX
bionys-641	146	5	contribute	contribute	VERB
bionys-641	146	6	to	to	ADP
bionys-641	146	7	malignant	malignant	ADJ
bionys-641	146	8	development	development	NOUN
bionys-641	146	9	.	.	PUNCT
bionys-641	147	1	it	it	PRON
bionys-641	147	2	is	be	AUX
bionys-641	147	3	also	also	ADV
bionys-641	147	4	linked	link	VERB
bionys-641	147	5	(	(	PUNCT
bionys-641	147	6	particularly	particularly	ADV
bionys-641	147	7	in	in	ADP
bionys-641	147	8	older	old	ADJ
bionys-641	147	9	species	specie	NOUN
bionys-641	147	10	)	)	PUNCT
bionys-641	147	11	to	to	ADP
bionys-641	147	12	the	the	DET
bionys-641	147	13	formation	formation	NOUN
bionys-641	147	14	of	of	ADP
bionys-641	147	15	protein	protein	NOUN
bionys-641	147	16	clumps	clump	NOUN
bionys-641	147	17	in	in	ADP
bionys-641	147	18	neurons	neuron	NOUN
bionys-641	147	19	and	and	CCONJ
bionys-641	147	20	the	the	DET
bionys-641	147	21	aftermath	aftermath	NOUN
bionys-641	147	22	of	of	ADP
bionys-641	147	23	neurodegenerative	neurodegenerative	ADJ
bionys-641	147	24	disorders	disorder	NOUN
bionys-641	147	25	such	such	ADJ
bionys-641	147	26	as	as	ADP
bionys-641	147	27	ad	ad	NOUN
bionys-641	147	28	(	(	PUNCT
bionys-641	147	29	barmaki	barmaki	NOUN
bionys-641	147	30	et	et	PROPN
bionys-641	147	31	al	al	PROPN
bionys-641	147	32	.	.	PROPN
bionys-641	147	33	,	,	PUNCT
bionys-641	147	34	2023	2023	NUM
bionys-641	147	35	)	)	PUNCT
bionys-641	147	36	.	.	PUNCT
bionys-641	148	1	autophagy	autophagy	NOUN
bionys-641	148	2	can	can	AUX
bionys-641	148	3	be	be	AUX
bionys-641	148	4	classified	classify	VERB
bionys-641	148	5	into	into	ADP
bionys-641	148	6	macro-	macro-	PROPN
bionys-641	148	7	,	,	PUNCT
bionys-641	148	8	micro-	micro-	NOUN
bionys-641	148	9	,	,	PUNCT
bionys-641	148	10	and	and	CCONJ
bionys-641	148	11	selective	selective	ADJ
bionys-641	148	12	autophagy	autophagy	NOUN
bionys-641	148	13	.	.	PUNCT
bionys-641	149	1	the	the	DET
bionys-641	149	2	most	most	ADV
bionys-641	149	3	well	well	ADV
bionys-641	149	4	-	-	PUNCT
bionys-641	149	5	discussed	discuss	VERB
bionys-641	149	6	type	type	NOUN
bionys-641	149	7	is	be	AUX
bionys-641	149	8	macroautophagy	macroautophagy	ADJ
bionys-641	149	9	.	.	PUNCT
bionys-641	150	1	in	in	ADP
bionys-641	150	2	macroautophagy	macroautophagy	ADJ
bionys-641	150	3	,	,	PUNCT
bionys-641	150	4	double	double	ADJ
bionys-641	150	5	-	-	PUNCT
bionys-641	150	6	membrane	membrane	NOUN
bionys-641	150	7	vesicles	vesicle	NOUN
bionys-641	150	8	known	know	VERB
bionys-641	150	9	as	as	SCONJ
bionys-641	150	10	autophagosomes	autophagosome	NOUN
bionys-641	150	11	envelop	envelop	VERB
bionys-641	150	12	the	the	DET
bionys-641	150	13	whole	whole	ADJ
bionys-641	150	14	cell	cell	NOUN
bionys-641	150	15	surface	surface	NOUN
bionys-641	150	16	.	.	PUNCT
bionys-641	151	1	these	these	DET
bionys-641	151	2	autophagosomes	autophagosome	NOUN
bionys-641	151	3	subsequently	subsequently	ADV
bionys-641	151	4	merge	merge	VERB
bionys-641	151	5	with	with	ADP
bionys-641	151	6	lysosomes	lysosome	NOUN
bionys-641	151	7	to	to	PART
bionys-641	151	8	form	form	VERB
bionys-641	151	9	autophagolysosomes	autophagolysosome	NOUN
bionys-641	151	10	,	,	PUNCT
bionys-641	151	11	where	where	SCONJ
bionys-641	151	12	the	the	DET
bionys-641	151	13	proteases	protease	NOUN
bionys-641	151	14	eliminate	eliminate	VERB
bionys-641	151	15	their	their	PRON
bionys-641	151	16	contents	content	NOUN
bionys-641	151	17	(	(	PUNCT
bionys-641	151	18	kroemer	kroemer	PROPN
bionys-641	151	19	&	&	CCONJ
bionys-641	151	20	levine	levine	PROPN
bionys-641	151	21	,	,	PUNCT
bionys-641	151	22	2008	2008	NUM
bionys-641	151	23	)	)	PUNCT
bionys-641	151	24	.	.	PUNCT
bionys-641	152	1	microautophagy	microautophagy	PROPN
bionys-641	152	2	occurs	occur	VERB
bionys-641	152	3	when	when	SCONJ
bionys-641	152	4	organelles	organelle	NOUN
bionys-641	152	5	or	or	CCONJ
bionys-641	152	6	cytosolic	cytosolic	ADJ
bionys-641	152	7	areas	area	NOUN
bionys-641	152	8	engage	engage	VERB
bionys-641	152	9	immediately	immediately	ADV
bionys-641	152	10	with	with	ADP
bionys-641	152	11	lysosomes	lysosome	NOUN
bionys-641	152	12	.	.	PUNCT
bionys-641	153	1	microautophagy	microautophagy	PROPN
bionys-641	153	2	is	be	AUX
bionys-641	153	3	considerably	considerably	ADV
bionys-641	153	4	more	more	ADV
bionys-641	153	5	targeted	targeted	ADJ
bionys-641	153	6	compared	compare	VERB
bionys-641	153	7	to	to	ADP
bionys-641	153	8	macroautophagy	macroautophagy	ADJ
bionys-641	153	9	and	and	CCONJ
bionys-641	153	10	can	can	AUX
bionys-641	153	11	be	be	AUX
bionys-641	153	12	initiated	initiate	VERB
bionys-641	153	13	by	by	ADP
bionys-641	153	14	signaling	signal	VERB
bionys-641	153	15	compounds	compound	NOUN
bionys-641	153	16	present	present	ADJ
bionys-641	153	17	on	on	ADP
bionys-641	153	18	the	the	DET
bionys-641	153	19	outer	outer	ADJ
bionys-641	153	20	layers	layer	NOUN
bionys-641	153	21	of	of	ADP
bionys-641	153	22	defective	defective	ADJ
bionys-641	153	23	organelles	organelle	NOUN
bionys-641	153	24	,	,	PUNCT
bionys-641	153	25	such	such	ADJ
bionys-641	153	26	as	as	ADP
bionys-641	153	27	peroxisomes	peroxisome	NOUN
bionys-641	153	28	and	and	CCONJ
bionys-641	153	29	mitochondria	mitochondria	NOUN
bionys-641	153	30	,	,	PUNCT
bionys-641	153	31	causing	cause	VERB
bionys-641	153	32	lysosomes	lysosome	NOUN
bionys-641	153	33	to	to	PART
bionys-641	153	34	fuse	fuse	VERB
bionys-641	153	35	with	with	ADP
bionys-641	153	36	these	these	DET
bionys-641	153	37	organelles	organelle	NOUN
bionys-641	153	38	(	(	PUNCT
bionys-641	153	39	settembre	settembre	PROPN
bionys-641	153	40	et	et	PROPN
bionys-641	153	41	al	al	PROPN
bionys-641	153	42	.	.	PROPN
bionys-641	153	43	,	,	PUNCT
bionys-641	153	44	2013	2013	NUM
bionys-641	153	45	)	)	PUNCT
bionys-641	153	46	.	.	PUNCT
bionys-641	154	1	selective	selective	ADJ
bionys-641	154	2	autophagy	autophagy	NOUN
bionys-641	154	3	,	,	PUNCT
bionys-641	154	4	also	also	ADV
bionys-641	154	5	referred	refer	VERB
bionys-641	154	6	to	to	ADP
bionys-641	154	7	as	as	ADP
bionys-641	154	8	chaperonemediated	chaperonemediate	VERB
bionys-641	154	9	autophagy	autophagy	NOUN
bionys-641	154	10	,	,	PUNCT
bionys-641	154	11	occurs	occur	VERB
bionys-641	154	12	when	when	SCONJ
bionys-641	154	13	a	a	DET
bionys-641	154	14	cytosolic	cytosolic	NOUN
bionys-641	154	15	chaperone	chaperone	NOUN
bionys-641	154	16	targets	target	NOUN
bionys-641	154	17	proteins	protein	NOUN
bionys-641	154	18	in	in	ADP
bionys-641	154	19	the	the	DET
bionys-641	154	20	cytoplasm	cytoplasm	NOUN
bionys-641	154	21	for	for	ADP
bionys-641	154	22	union	union	NOUN
bionys-641	154	23	with	with	ADP
bionys-641	154	24	lysosomes	lysosome	NOUN
bionys-641	154	25	via	via	ADP
bionys-641	154	26	communications	communication	NOUN
bionys-641	154	27	between	between	ADP
bionys-641	154	28	the	the	DET
bionys-641	154	29	chaperone	chaperone	NOUN
bionys-641	154	30	and	and	CCONJ
bionys-641	154	31	pentapeptides	pentapeptide	NOUN
bionys-641	154	32	found	find	VERB
bionys-641	154	33	in	in	ADP
bionys-641	154	34	the	the	DET
bionys-641	154	35	substrate	substrate	NOUN
bionys-641	154	36	's	's	PART
bionys-641	154	37	amino	amino	NOUN
bionys-641	154	38	acid	acid	NOUN
bionys-641	154	39	sequence	sequence	NOUN
bionys-641	154	40	(	(	PUNCT
bionys-641	154	41	choi	choi	NOUN
bionys-641	154	42	et	et	PROPN
bionys-641	154	43	al	al	PROPN
bionys-641	154	44	.	.	PROPN
bionys-641	154	45	,	,	PUNCT
bionys-641	154	46	2023	2023	NUM
bionys-641	154	47	)	)	PUNCT
bionys-641	154	48	.	.	PUNCT
bionys-641	155	1	the	the	DET
bionys-641	155	2	substrate	substrate	NOUN
bionys-641	155	3	protein	protein	NOUN
bionys-641	155	4	attaches	attach	VERB
bionys-641	155	5	to	to	ADP
bionys-641	155	6	the	the	DET
bionys-641	155	7	lysosomal	lysosomal	ADJ
bionys-641	155	8	receptor	receptor	NOUN
bionys-641	155	9	lamp-2a	lamp-2a	PUNCT
bionys-641	155	10	and	and	CCONJ
bionys-641	155	11	is	be	AUX
bionys-641	155	12	transported	transport	VERB
bionys-641	155	13	to	to	ADP
bionys-641	155	14	the	the	DET
bionys-641	155	15	lysosome	lysosome	NOUN
bionys-641	155	16	for	for	ADP
bionys-641	155	17	breakdown	breakdown	NOUN
bionys-641	155	18	(	(	PUNCT
bionys-641	155	19	bandyopadhyay	bandyopadhyay	NOUN
bionys-641	155	20	et	et	NOUN
bionys-641	155	21	al	al	PROPN
bionys-641	155	22	.	.	PROPN
bionys-641	155	23	,	,	PUNCT
bionys-641	155	24	2008	2008	NUM
bionys-641	155	25	)	)	PUNCT
bionys-641	155	26	.	.	PUNCT
bionys-641	156	1	the	the	DET
bionys-641	156	2	autophagy	autophagy	ADJ
bionys-641	156	3	process	process	NOUN
bionys-641	156	4	starts	start	VERB
bionys-641	156	5	with	with	ADP
bionys-641	156	6	the	the	DET
bionys-641	156	7	action	action	NOUN
bionys-641	156	8	of	of	ADP
bionys-641	156	9	the	the	DET
bionys-641	156	10	ulk1	ulk1	PROPN
bionys-641	156	11	complex	complex	PROPN
bionys-641	156	12	.	.	PUNCT
bionys-641	157	1	a	a	DET
bionys-641	157	2	phosphoinositide	phosphoinositide	NOUN
bionys-641	157	3	-	-	PUNCT
bionys-641	157	4	kinase	kinase	NOUN
bionys-641	157	5	(	(	PUNCT
bionys-641	157	6	p13k	p13k	NOUN
bionys-641	157	7	)	)	PUNCT
bionys-641	157	8	complex	complex	NOUN
bionys-641	157	9	is	be	AUX
bionys-641	157	10	needed	need	VERB
bionys-641	157	11	to	to	PART
bionys-641	157	12	produce	produce	VERB
bionys-641	157	13	a	a	DET
bionys-641	157	14	phagophore	phagophore	NOUN
bionys-641	157	15	,	,	PUNCT
bionys-641	157	16	mainly	mainly	ADV
bionys-641	157	17	the	the	DET
bionys-641	157	18	class	class	NOUN
bionys-641	157	19	iii	iii	NOUN
bionys-641	157	20	complex	complex	NOUN
bionys-641	157	21	.	.	PUNCT
bionys-641	158	1	pi3k	pi3k	NOUN
bionys-641	158	2	itself	itself	PRON
bionys-641	158	3	can	can	AUX
bionys-641	158	4	be	be	AUX
bionys-641	158	5	classified	classify	VERB
bionys-641	158	6	into	into	ADP
bionys-641	158	7	four	four	NUM
bionys-641	158	8	classes	class	NOUN
bionys-641	158	9	(	(	PUNCT
bionys-641	158	10	class	class	PROPN
bionys-641	158	11	ia	ia	PROPN
bionys-641	158	12	,	,	PUNCT
bionys-641	158	13	ib	ib	PROPN
bionys-641	158	14	,	,	PUNCT
bionys-641	158	15	ii	ii	PROPN
bionys-641	158	16	,	,	PUNCT
bionys-641	158	17	and	and	CCONJ
bionys-641	158	18	iii	iii	X
bionys-641	158	19	)	)	PUNCT
bionys-641	158	20	with	with	ADP
bionys-641	158	21	two	two	NUM
bionys-641	158	22	main	main	ADJ
bionys-641	158	23	subunit	subunit	NOUN
bionys-641	158	24	types	type	NOUN
bionys-641	158	25	:	:	PUNCT
bionys-641	158	26	a	a	DET
bionys-641	158	27	regulatory	regulatory	ADJ
bionys-641	158	28	and	and	CCONJ
bionys-641	158	29	a	a	DET
bionys-641	158	30	catalytic	catalytic	ADJ
bionys-641	158	31	subunit	subunit	NOUN
bionys-641	158	32	.	.	PUNCT
bionys-641	159	1	class	class	PROPN
bionys-641	159	2	ia	ia	PROPN
bionys-641	159	3	,	,	PUNCT
bionys-641	159	4	the	the	DET
bionys-641	159	5	most	most	ADV
bionys-641	159	6	studied	studied	ADJ
bionys-641	159	7	type	type	NOUN
bionys-641	159	8	of	of	ADP
bionys-641	159	9	pi3k	pi3k	NOUN
bionys-641	159	10	complex	complex	NOUN
bionys-641	159	11	,	,	PUNCT
bionys-641	159	12	has	have	VERB
bionys-641	159	13	five	five	NUM
bionys-641	159	14	subunits	subunit	NOUN
bionys-641	159	15	(	(	PUNCT
bionys-641	159	16	p50α	p50α	NOUN
bionys-641	159	17	,	,	PUNCT
bionys-641	159	18	p55α	p55α	NOUN
bionys-641	159	19	,	,	PUNCT
bionys-641	159	20	p55γ	p55γ	NOUN
bionys-641	159	21	,	,	PUNCT
bionys-641	159	22	p85β	p85β	ADJ
bionys-641	159	23	,	,	PUNCT
bionys-641	159	24	and	and	CCONJ
bionys-641	159	25	p85α	p85α	NUM
bionys-641	159	26	)	)	PUNCT
bionys-641	159	27	.	.	PUNCT
bionys-641	160	1	meanwhile	meanwhile	ADV
bionys-641	160	2	,	,	PUNCT
bionys-641	160	3	the	the	DET
bionys-641	160	4	one	one	NUM
bionys-641	160	5	specific	specific	NOUN
bionys-641	160	6	for	for	ADP
bionys-641	160	7	the	the	DET
bionys-641	160	8	autophagy	autophagy	ADJ
bionys-641	160	9	process	process	NOUN
bionys-641	160	10	has	have	VERB
bionys-641	160	11	vps15	vps15	NOUN
bionys-641	160	12	as	as	ADP
bionys-641	160	13	the	the	DET
bionys-641	160	14	regulatory	regulatory	ADJ
bionys-641	160	15	and	and	CCONJ
bionys-641	160	16	vps34	vps34	ADV
bionys-641	160	17	as	as	ADP
bionys-641	160	18	the	the	DET
bionys-641	160	19	catalytic	catalytic	ADJ
bionys-641	160	20	subunit	subunit	NOUN
bionys-641	160	21	to	to	PART
bionys-641	160	22	trigger	trigger	VERB
bionys-641	160	23	the	the	DET
bionys-641	160	24	conversion	conversion	NOUN
bionys-641	160	25	of	of	ADP
bionys-641	160	26	phosphatidylinositol	phosphatidylinositol	NOUN
bionys-641	160	27	(	(	PUNCT
bionys-641	160	28	pi	pi	NOUN
bionys-641	160	29	)	)	PUNCT
bionys-641	160	30	to	to	PART
bionys-641	160	31	phosphatidylinositol	phosphatidylinositol	VERB
bionys-641	160	32	3	3	NUM
bionys-641	160	33	-	-	NOUN
bionys-641	160	34	phosphate	phosphate	NOUN
bionys-641	160	35	(	(	PUNCT
bionys-641	160	36	pi(3	pi(3	NOUN
bionys-641	160	37	)	)	PUNCT
bionys-641	160	38	p	p	NOUN
bionys-641	160	39	)	)	PUNCT
bionys-641	160	40	(	(	PUNCT
bionys-641	160	41	engelman	engelman	PROPN
bionys-641	160	42	et	et	PROPN
bionys-641	160	43	al	al	PROPN
bionys-641	160	44	.	.	PROPN
bionys-641	160	45	,	,	PUNCT
bionys-641	160	46	2006	2006	NUM
bionys-641	160	47	)	)	PUNCT
bionys-641	160	48	.	.	PUNCT
bionys-641	161	1	the	the	DET
bionys-641	161	2	atg16l	atg16l	PROPN
bionys-641	161	3	,	,	PUNCT
bionys-641	161	4	atg5	atg5	PROPN
bionys-641	161	5	,	,	PUNCT
bionys-641	161	6	and	and	CCONJ
bionys-641	161	7	atg12	atg12	NOUN
bionys-641	161	8	complexes	complex	NOUN
bionys-641	161	9	,	,	PUNCT
bionys-641	161	10	together	together	ADV
bionys-641	161	11	with	with	ADP
bionys-641	161	12	the	the	DET
bionys-641	161	13	lipidated	lipidate	VERB
bionys-641	161	14	microtubule	microtubule	NOUN
bionys-641	161	15	-	-	PUNCT
bionys-641	161	16	associated	associate	VERB
bionys-641	161	17	protein	protein	NOUN
bionys-641	161	18	light	light	NOUN
bionys-641	161	19	chain	chain	NOUN
bionys-641	161	20	3	3	NUM
bionys-641	161	21	(	(	PUNCT
bionys-641	161	22	lc3ii	lc3ii	PROPN
bionys-641	161	23	)	)	PUNCT
bionys-641	161	24	,	,	PUNCT
bionys-641	161	25	facilitate	facilitate	VERB
bionys-641	161	26	phagophore	phagophore	ADJ
bionys-641	161	27	elongation	elongation	NOUN
bionys-641	161	28	and	and	CCONJ
bionys-641	161	29	serve	serve	VERB
bionys-641	161	30	as	as	ADP
bionys-641	161	31	prerequisites	prerequisite	NOUN
bionys-641	161	32	for	for	ADP
bionys-641	161	33	autophagosome	autophagosome	VERB
bionys-641	161	34	construction	construction	NOUN
bionys-641	161	35	(	(	PUNCT
bionys-641	161	36	park	park	NOUN
bionys-641	161	37	et	et	PROPN
bionys-641	161	38	al	al	PROPN
bionys-641	161	39	.	.	PROPN
bionys-641	161	40	,	,	PUNCT
bionys-641	161	41	2016	2016	NUM
bionys-641	161	42	;	;	PUNCT
bionys-641	161	43	li	li	PROPN
bionys-641	161	44	et	et	PROPN
bionys-641	161	45	al	al	PROPN
bionys-641	161	46	.	.	PROPN
bionys-641	161	47	,	,	PUNCT
bionys-641	161	48	2020	2020	NUM
bionys-641	161	49	)	)	PUNCT
bionys-641	161	50	.	.	PUNCT
bionys-641	162	1	the	the	DET
bionys-641	162	2	p60	p60	NOUN
bionys-641	162	3	protein	protein	NOUN
bionys-641	162	4	interacts	interact	VERB
bionys-641	162	5	with	with	ADP
bionys-641	162	6	other	other	ADJ
bionys-641	162	7	proteins	protein	NOUN
bionys-641	162	8	and	and	CCONJ
bionys-641	162	9	is	be	AUX
bionys-641	162	10	annihilated	annihilate	VERB
bionys-641	162	11	.	.	PUNCT
bionys-641	163	1	p60	p60	NOUN
bionys-641	163	2	interacts	interact	VERB
bionys-641	163	3	with	with	ADP
bionys-641	163	4	lc3ii	lc3ii	ADV
bionys-641	163	5	,	,	PUNCT
bionys-641	163	6	resulting	result	VERB
bionys-641	163	7	in	in	ADP
bionys-641	163	8	the	the	DET
bionys-641	163	9	formation	formation	NOUN
bionys-641	163	10	of	of	ADP
bionys-641	163	11	autophagosomes	autophagosome	NOUN
bionys-641	163	12	that	that	PRON
bionys-641	163	13	engulf	engulf	VERB
bionys-641	163	14	target	target	NOUN
bionys-641	163	15	proteins	protein	NOUN
bionys-641	163	16	and	and	CCONJ
bionys-641	163	17	organelles	organelle	NOUN
bionys-641	163	18	.	.	PUNCT
bionys-641	164	1	autophagosomes	autophagosome	NOUN
bionys-641	164	2	then	then	ADV
bionys-641	164	3	combine	combine	VERB
bionys-641	164	4	with	with	ADP
bionys-641	164	5	lysosomes	lysosome	NOUN
bionys-641	164	6	,	,	PUNCT
bionys-641	164	7	whose	whose	DET
bionys-641	164	8	contents	content	NOUN
bionys-641	164	9	are	be	AUX
bionys-641	164	10	digested	digest	VERB
bionys-641	164	11	(	(	PUNCT
bionys-641	164	12	dice	dice	NOUN
bionys-641	164	13	,	,	PUNCT
bionys-641	164	14	2007	2007	NUM
bionys-641	164	15	)	)	PUNCT
bionys-641	164	16	.	.	PUNCT
bionys-641	165	1	comparison	comparison	NOUN
bionys-641	165	2	of	of	ADP
bionys-641	165	3	different	different	ADJ
bionys-641	165	4	major	major	ADJ
bionys-641	165	5	rcd	rcd	PROPN
bionys-641	165	6	types	type	NOUN
bionys-641	165	7	is	be	AUX
bionys-641	165	8	available	available	ADJ
bionys-641	165	9	in	in	ADP
bionys-641	165	10	tab	tab	NOUN
bionys-641	165	11	.	.	PUNCT
bionys-641	166	1	1	1	X
bionys-641	166	2	.	.	X
bionys-641	166	3	other	other	ADJ
bionys-641	166	4	rcd	rcd	PROPN
bionys-641	166	5	classifications	classification	NOUN
bionys-641	166	6	in	in	ADP
bionys-641	166	7	addition	addition	NOUN
bionys-641	166	8	to	to	ADP
bionys-641	166	9	the	the	DET
bionys-641	166	10	previously	previously	ADV
bionys-641	166	11	described	describe	VERB
bionys-641	166	12	rcd	rcd	PROPN
bionys-641	166	13	types	type	NOUN
bionys-641	166	14	,	,	PUNCT
bionys-641	166	15	several	several	ADJ
bionys-641	166	16	other	other	ADJ
bionys-641	166	17	kinds	kind	NOUN
bionys-641	166	18	will	will	AUX
bionys-641	166	19	be	be	AUX
bionys-641	166	20	discussed	discuss	VERB
bionys-641	166	21	below	below	ADV
bionys-641	166	22	.	.	PUNCT
bionys-641	167	1	this	this	PRON
bionys-641	167	2	includes	include	VERB
bionys-641	167	3	parthanatos	parthanato	NOUN
bionys-641	167	4	,	,	PUNCT
bionys-641	167	5	entosis	entosis	NOUN
bionys-641	167	6	,	,	PUNCT
bionys-641	167	7	neutrophil	neutrophil	ADJ
bionys-641	167	8	extracellular	extracellular	ADJ
bionys-641	167	9	traps	trap	NOUN
bionys-641	167	10	(	(	PUNCT
bionys-641	167	11	net)osis	net)osis	NOUN
bionys-641	167	12	–	–	PUNCT
bionys-641	167	13	suicidal	suicidal	ADJ
bionys-641	167	14	pathway	pathway	NOUN
bionys-641	167	15	,	,	PUNCT
bionys-641	167	16	lysosome	lysosome	NOUN
bionys-641	167	17	-	-	PUNCT
bionys-641	167	18	dependent	dependent	ADJ
bionys-641	167	19	cell	cell	NOUN
bionys-641	167	20	death	death	NOUN
bionys-641	167	21	(	(	PUNCT
bionys-641	167	22	lcd	lcd	NOUN
bionys-641	167	23	)	)	PUNCT
bionys-641	167	24	,	,	PUNCT
bionys-641	167	25	alkaliptosis	alkaliptosis	ADJ
bionys-641	167	26	,	,	PUNCT
bionys-641	167	27	oxeiptosis	oxeiptosis	NOUN
bionys-641	167	28	,	,	PUNCT
bionys-641	167	29	and	and	CCONJ
bionys-641	167	30	anoikis	anoiki	NOUN
bionys-641	167	31	(	(	PUNCT
bionys-641	167	32	galluzzi	galluzzi	NOUN
bionys-641	167	33	et	et	PROPN
bionys-641	167	34	al	al	PROPN
bionys-641	167	35	.	.	PROPN
bionys-641	167	36	,	,	PUNCT
bionys-641	167	37	2018	2018	NUM
bionys-641	167	38	;	;	PUNCT
bionys-641	167	39	khan	khan	PROPN
bionys-641	167	40	et	et	PROPN
bionys-641	167	41	al	al	PROPN
bionys-641	167	42	.	.	PROPN
bionys-641	167	43	,	,	PUNCT
bionys-641	167	44	2022	2022	NUM
bionys-641	167	45	)	)	PUNCT
bionys-641	167	46	.	.	PUNCT
bionys-641	168	1	parthanatos	parthanato	NOUN
bionys-641	168	2	is	be	AUX
bionys-641	168	3	an	an	DET
bionys-641	168	4	rcd	rcd	PROPN
bionys-641	168	5	that	that	PRON
bionys-641	168	6	depends	depend	VERB
bionys-641	168	7	on	on	ADP
bionys-641	168	8	poly(adpribose	poly(adpribose	NOUN
bionys-641	168	9	)	)	PUNCT
bionys-641	168	10	polymerase	polymerase	NOUN
bionys-641	168	11	1	1	NUM
bionys-641	168	12	(	(	PUNCT
bionys-641	168	13	parp1	parp1	PROPN
bionys-641	168	14	)	)	PUNCT
bionys-641	168	15	(	(	PUNCT
bionys-641	168	16	conrad	conrad	PROPN
bionys-641	168	17	et	et	PROPN
bionys-641	168	18	al	al	PROPN
bionys-641	168	19	.	.	PROPN
bionys-641	168	20	,	,	PUNCT
bionys-641	168	21	2016	2016	NUM
bionys-641	168	22	)	)	PUNCT
bionys-641	168	23	.	.	PUNCT
bionys-641	169	1	biologica	biologica	PROPN
bionys-641	169	2	nyssana	nyssana	PROPN
bionys-641	169	3	●	●	PUNCT
bionys-641	169	4	16	16	NUM
bionys-641	169	5	(	(	PUNCT
bionys-641	169	6	2	2	NUM
bionys-641	169	7	)	)	PUNCT
bionys-641	169	8	december	december	PROPN
bionys-641	169	9	2025	2025	NUM
bionys-641	169	10	:	:	PUNCT
bionys-641	169	11	liana	liana	NOUN
bionys-641	169	12	et	et	PROPN
bionys-641	169	13	al	al	PROPN
bionys-641	169	14	.	.	PUNCT
bionys-641	170	1	●	●	PUNCT
bionys-641	170	2	cell	cell	NOUN
bionys-641	170	3	deaths	death	NOUN
bionys-641	170	4	and	and	CCONJ
bionys-641	170	5	their	their	PRON
bionys-641	170	6	associated	associate	VERB
bionys-641	170	7	mechanisms	mechanism	NOUN
bionys-641	170	8	ta	ta	X
bionys-641	170	9	bl	bl	VERB
bionys-641	170	10	e	e	PROPN
bionys-641	170	11	1	1	NUM
bionys-641	170	12	.	.	PUNCT
bionys-641	171	1	c	c	AUX
bionys-641	171	2	om	om	PROPN
bionys-641	171	3	pa	pa	PROPN
bionys-641	171	4	ris	ris	PROPN
bionys-641	171	5	on	on	ADP
bionys-641	171	6	o	o	PROPN
bionys-641	171	7	f	f	PROPN
bionys-641	171	8	m	m	PROPN
bionys-641	171	9	aj	aj	PROPN
bionys-641	171	10	or	or	CCONJ
bionys-641	171	11	re	re	AUX
bionys-641	171	12	gu	gu	NOUN
bionys-641	171	13	la	la	PROPN
bionys-641	171	14	te	te	PROPN
bionys-641	171	15	d	d	X
bionys-641	171	16	ce	ce	PROPN
bionys-641	171	17	ll	ll	AUX
bionys-641	171	18	de	de	PROPN
bionys-641	171	19	at	at	ADP
bionys-641	171	20	h	h	NOUN
bionys-641	171	21	pa	pa	PROPN
bionys-641	171	22	th	th	PROPN
bionys-641	171	23	w	w	PROPN
bionys-641	171	24	ay	ay	PROPN
bionys-641	171	25	s	s	PART
bionys-641	171	26	ac	ac	ADJ
bionys-641	171	27	sl	sl	PROPN
bionys-641	171	28	4	4	NUM
bionys-641	171	29	:	:	PUNCT
bionys-641	171	30	a	a	DET
bionys-641	171	31	cy	cy	PROPN
bionys-641	171	32	l	l	PROPN
bionys-641	171	33	-	-	NOUN
bionys-641	171	34	c	c	VERB
bionys-641	171	35	oa	oa	PROPN
bionys-641	171	36	s	s	X
bionys-641	171	37	yn	yn	X
bionys-641	171	38	th	th	X
bionys-641	171	39	et	et	NOUN
bionys-641	171	40	as	as	ADP
bionys-641	171	41	e	e	PROPN
bionys-641	171	42	lo	lo	PROPN
bionys-641	172	1	ng	ng	PROPN
bionys-641	172	2	c	c	X
bionys-641	172	3	ha	ha	INTJ
bionys-641	172	4	in	in	ADP
bionys-641	172	5	f	f	PROPN
bionys-641	172	6	am	be	AUX
bionys-641	172	7	ily	ily	ADV
bionys-641	172	8	m	m	VERB
bionys-641	172	9	em	em	PRON
bionys-641	172	10	be	be	AUX
bionys-641	172	11	r	r	NOUN
bionys-641	172	12	4	4	NUM
bionys-641	172	13	,	,	PUNCT
bionys-641	172	14	a	a	DET
bionys-641	172	15	pa	pa	PROPN
bionys-641	172	16	f1	f1	NOUN
bionys-641	172	17	:	:	PUNCT
bionys-641	173	1	a	a	DET
bionys-641	173	2	po	po	NOUN
bionys-641	173	3	pt	pt	X
bionys-641	173	4	ot	ot	INTJ
bionys-641	173	5	ic	ic	PROPN
bionys-641	173	6	p	p	X
bionys-641	173	7	ep	ep	PROPN
bionys-641	173	8	tid	tid	PROPN
bionys-641	173	9	as	as	ADP
bionys-641	173	10	e	e	PROPN
bionys-641	173	11	ac	ac	PROPN
bionys-641	173	12	tiv	tiv	PROPN
bionys-641	173	13	at	at	ADP
bionys-641	173	14	in	in	ADP
bionys-641	173	15	g	g	PROPN
bionys-641	173	16	fa	fa	INTJ
bionys-641	173	17	ct	ct	NOUN
bionys-641	173	18	or	or	CCONJ
bionys-641	173	19	1	1	NUM
bionys-641	173	20	,	,	PUNCT
bionys-641	173	21	a	a	DET
bionys-641	173	22	tg	tg	X
bionys-641	173	23	:	:	PUNCT
bionys-641	173	24	a	a	DET
bionys-641	173	25	ut	ut	PROPN
bionys-641	173	26	op	op	NOUN
bionys-641	173	27	ha	ha	INTJ
bionys-641	173	28	gy	gy	PROPN
bionys-641	173	29	-re	-re	X
bionys-641	173	30	la	la	NOUN
bionys-641	173	31	te	te	PROPN
bionys-641	173	32	d	d	X
bionys-641	173	33	pr	pr	X
bionys-641	173	34	ot	ot	INTJ
bionys-641	173	35	ei	ei	INTJ
bionys-641	173	36	ns	ns	INTJ
bionys-641	173	37	,	,	PUNCT
bionys-641	173	38	b	b	PROPN
bionys-641	173	39	c	c	NOUN
bionys-641	173	40	l2	l2	NOUN
bionys-641	173	41	:	:	PUNCT
bionys-641	173	42	bce	bce	PROPN
bionys-641	174	1	ll	ll	AUX
bionys-641	174	2	ly	ly	VERB
bionys-641	174	3	m	m	VERB
bionys-641	174	4	ph	ph	ADJ
bionys-641	174	5	om	om	PROPN
bionys-641	174	6	a	a	DET
bionys-641	174	7	2	2	NUM
bionys-641	174	8	,	,	PUNCT
bionys-641	174	9	d	d	PROPN
bionys-641	174	10	a	a	DET
bionys-641	174	11	m	m	NOUN
bionys-641	174	12	ps	ps	NOUN
bionys-641	174	13	:	:	PUNCT
bionys-641	174	14	d	d	X
bionys-641	174	15	am	be	AUX
bionys-641	174	16	ag	ag	PROPN
bionys-641	174	17	eas	eas	PROPN
bionys-641	174	18	so	so	SCONJ
bionys-641	174	19	ci	ci	PROPN
bionys-641	174	20	at	at	ADP
bionys-641	174	21	ed	ed	PROPN
bionys-641	174	22	m	m	VERB
bionys-641	174	23	ol	ol	PROPN
bionys-641	174	24	ec	ec	PROPN
bionys-641	174	25	ul	ul	INTJ
bionys-641	174	26	ar	ar	PROPN
bionys-641	174	27	p	p	PROPN
bionys-641	174	28	at	at	ADP
bionys-641	174	29	te	te	PROPN
bionys-641	174	30	rn	rn	PROPN
bionys-641	174	31	s	s	PROPN
bionys-641	174	32	,	,	PUNCT
bionys-641	174	33	d	d	PROPN
bionys-641	174	34	n	n	PRON
bionys-641	174	35	a	a	PRON
bionys-641	174	36	:	:	PUNCT
bionys-641	174	37	d	d	X
bionys-641	174	38	eo	eo	INTJ
bionys-641	174	39	xy	xy	PROPN
bionys-641	174	40	rib	rib	NOUN
bionys-641	174	41	on	on	ADP
bionys-641	174	42	uc	uc	PROPN
bionys-641	174	43	le	le	PROPN
bionys-641	174	44	ic	ic	PROPN
bionys-641	175	1	a	a	DET
bionys-641	175	2	ci	ci	PROPN
bionys-641	175	3	d	d	PROPN
bionys-641	175	4	,	,	PUNCT
bionys-641	175	5	f	f	PROPN
bionys-641	175	6	as	as	ADP
bionys-641	175	7	l	l	PROPN
bionys-641	175	8	:	:	PUNCT
bionys-641	175	9	f	f	PROPN
bionys-641	175	10	as	as	ADP
bionys-641	175	11	l	l	PROPN
bionys-641	175	12	ig	ig	PROPN
bionys-641	175	13	an	an	PROPN
bionys-641	175	14	d	d	PROPN
bionys-641	175	15	,	,	PUNCT
bionys-641	175	16	g	g	PROPN
bionys-641	175	17	px	px	PROPN
bionys-641	175	18	4	4	NUM
bionys-641	175	19	:	:	PUNCT
bionys-641	175	20	g	g	PROPN
bionys-641	175	21	lu	lu	INTJ
bionys-641	175	22	ta	ta	X
bionys-641	175	23	th	th	X
bionys-641	175	24	io	io	X
bionys-641	175	25	ne	ne	PROPN
bionys-641	175	26	p	p	PROPN
bionys-641	175	27	er	er	INTJ
bionys-641	175	28	ox	ox	NOUN
bionys-641	175	29	i	i	PROPN
bionys-641	175	30	d	d	PROPN
bionys-641	175	31	as	as	ADP
bionys-641	175	32	e	e	X
bionys-641	175	33	4	4	NUM
bionys-641	175	34	,	,	PUNCT
bionys-641	175	35	g	g	PROPN
bionys-641	175	36	sd	sd	ADP
bionys-641	175	37	m	m	NOUN
bionys-641	175	38	d	d	NOUN
bionys-641	175	39	:	:	PUNCT
bionys-641	175	40	g	g	NOUN
bionys-641	175	41	as	as	ADP
bionys-641	175	42	de	de	PROPN
bionys-641	175	43	rm	rm	PROPN
bionys-641	175	44	in	in	ADP
bionys-641	175	45	d	d	PROPN
bionys-641	175	46	,	,	PUNCT
bionys-641	175	47	g	g	PROPN
bionys-641	175	48	sd	sd	NOUN
bionys-641	175	49	m	m	ADJ
bionys-641	175	50	e	e	NOUN
bionys-641	175	51	:	:	PUNCT
bionys-641	175	52	g	g	NOUN
bionys-641	175	53	as	as	ADP
bionys-641	175	54	de	de	PROPN
bionys-641	175	55	rm	rm	PROPN
bionys-641	175	56	in	in	ADP
bionys-641	175	57	e	e	PROPN
bionys-641	175	58	,	,	PUNCT
bionys-641	175	59	i	i	PRON
bionys-641	175	60	l1β	l1β	X
bionys-641	175	61	:	:	PUNCT
bionys-641	176	1	i	i	PRON
bionys-641	176	2	nt	not	PART
bionys-641	176	3	er	er	INTJ
bionys-641	176	4	le	le	X
bionys-641	176	5	uk	uk	PROPN
bionys-641	176	6	in	in	ADP
bionys-641	176	7	-1	-1	PROPN
bionys-641	176	8	b	b	X
bionys-641	176	9	et	et	PROPN
bionys-641	176	10	a	a	PROPN
bionys-641	176	11	,	,	PUNCT
bionys-641	176	12	il	il	PROPN
bionys-641	176	13	-1	-1	NOUN
bionys-641	176	14	8	8	NUM
bionys-641	176	15	:	:	PUNCT
bionys-641	176	16	in	in	ADP
bionys-641	176	17	te	te	PROPN
bionys-641	176	18	rle	rle	PROPN
bionys-641	176	19	uk	uk	PROPN
bionys-641	176	20	in	in	ADP
bionys-641	176	21	-1	-1	PROPN
bionys-641	176	22	8	8	NUM
bionys-641	176	23	,	,	PUNCT
bionys-641	176	24	l	l	NOUN
bionys-641	176	25	ps	ps	NOUN
bionys-641	176	26	:	:	PUNCT
bionys-641	176	27	l	l	NOUN
bionys-641	176	28	ip	ip	NOUN
bionys-641	176	29	op	op	NOUN
bionys-641	176	30	ol	ol	PROPN
bionys-641	176	31	ys	ys	PROPN
bionys-641	176	32	ac	ac	PROPN
bionys-641	176	33	ch	ch	PROPN
bionys-641	176	34	ar	ar	PROPN
bionys-641	176	35	i	i	PROPN
bionys-641	176	36	d	d	PROPN
bionys-641	176	37	e	e	PROPN
bionys-641	176	38	,	,	PUNCT
bionys-641	176	39	m	m	VERB
bionys-641	176	40	lk	lk	PROPN
bionys-641	176	41	l	l	NOUN
bionys-641	176	42	:	:	PUNCT
bionys-641	176	43	m	m	VERB
bionys-641	176	44	ix	ix	ADV
bionys-641	176	45	ed	ed	PROPN
bionys-641	176	46	l	l	PROPN
bionys-641	176	47	in	in	ADP
bionys-641	176	48	ea	ea	PROPN
bionys-641	176	49	ge	ge	PROPN
bionys-641	176	50	k	k	PROPN
bionys-641	176	51	in	in	ADV
bionys-641	176	52	as	as	SCONJ
bionys-641	176	53	e	e	PROPN
bionys-641	176	54	d	d	X
bionys-641	176	55	om	om	PROPN
bionys-641	176	56	ai	ai	VERB
bionys-641	176	57	nli	nli	PROPN
bionys-641	176	58	ke	ke	PROPN
bionys-641	176	59	p	p	PROPN
bionys-641	176	60	se	se	PROPN
bionys-641	176	61	ud	ud	INTJ
bionys-641	176	62	ok	ok	INTJ
bionys-641	176	63	in	in	ADV
bionys-641	176	64	as	as	ADP
bionys-641	176	65	e	e	NOUN
bionys-641	176	66	,	,	PUNCT
bionys-641	176	67	m	m	VERB
bionys-641	176	68	to	to	ADP
bionys-641	176	69	r	r	NOUN
bionys-641	176	70	:	:	PUNCT
bionys-641	176	71	m	m	VERB
bionys-641	176	72	am	be	AUX
bionys-641	176	73	m	m	PROPN
bionys-641	176	74	al	al	PROPN
bionys-641	176	75	ia	ia	PROPN
bionys-641	176	76	n	n	ADV
bionys-641	176	77	ta	ta	X
bionys-641	176	78	rg	rg	INTJ
bionys-641	176	79	et	et	PROPN
bionys-641	177	1	o	o	NOUN
bionys-641	178	1	f	f	X
bionys-641	179	1	r	r	NOUN
bionys-641	179	2	ap	ap	PROPN
bionys-641	179	3	am	be	AUX
bionys-641	179	4	yc	yc	NOUN
bionys-641	179	5	in	in	ADV
bionys-641	179	6	,	,	PUNCT
bionys-641	179	7	p	p	X
bionys-641	179	8	a	a	DET
bionys-641	179	9	m	m	NOUN
bionys-641	179	10	ps	ps	NOUN
bionys-641	179	11	:	:	PUNCT
bionys-641	179	12	p	p	NOUN
bionys-641	179	13	at	at	ADP
bionys-641	179	14	ho	ho	PROPN
bionys-641	179	15	ge	ge	PROPN
bionys-641	180	1	nas	nas	PROPN
bionys-641	180	2	so	so	ADV
bionys-641	180	3	ci	ci	PROPN
bionys-641	181	1	at	at	ADP
bionys-641	181	2	ed	ed	PROPN
bionys-641	181	3	m	m	VERB
bionys-641	181	4	ol	ol	PROPN
bionys-641	181	5	ec	ec	PROPN
bionys-641	181	6	ul	ul	INTJ
bionys-641	181	7	ar	ar	PROPN
bionys-641	181	8	p	p	PROPN
bionys-641	181	9	at	at	ADP
bionys-641	181	10	te	te	PROPN
bionys-641	181	11	rn	rn	PROPN
bionys-641	181	12	s	s	PROPN
bionys-641	181	13	,	,	PUNCT
bionys-641	181	14	p	p	NOUN
bionys-641	181	15	u	u	X
bionys-641	181	16	fa	fa	PROPN
bionys-641	181	17	s	s	PROPN
bionys-641	181	18	:	:	PUNCT
bionys-641	181	19	p	p	PROPN
bionys-641	181	20	ol	ol	PROPN
bionys-641	181	21	yu	yu	PROPN
bionys-641	181	22	ns	ns	PROPN
bionys-641	181	23	at	at	ADP
bionys-641	181	24	ur	ur	INTJ
bionys-641	181	25	at	at	ADP
bionys-641	181	26	ed	ed	PROPN
bionys-641	181	27	f	f	PROPN
bionys-641	181	28	at	at	ADP
bionys-641	181	29	ty	ty	INTJ
bionys-641	181	30	ac	ac	PROPN
bionys-641	182	1	i	i	PROPN
bionys-641	182	2	d	d	PROPN
bionys-641	182	3	s	s	PROPN
bionys-641	182	4	,	,	PUNCT
bionys-641	182	5	r	r	NOUN
bionys-641	182	6	ip	ip	NOUN
bionys-641	182	7	k	k	NOUN
bionys-641	182	8	1	1	NUM
bionys-641	182	9	:	:	PUNCT
bionys-641	182	10	r	r	NOUN
bionys-641	182	11	ec	ec	PROPN
bionys-641	182	12	ep	ep	PROPN
bionys-641	182	13	to	to	ADP
bionys-641	182	14	r	r	VERB
bionys-641	182	15	-	-	PUNCT
bionys-641	182	16	i	i	PRON
bionys-641	182	17	nt	not	PART
bionys-641	182	18	er	er	INTJ
bionys-641	182	19	ac	ac	PROPN
bionys-641	182	20	tin	tin	PROPN
bionys-641	182	21	g	g	PROPN
bionys-641	182	22	se	se	PROPN
bionys-641	182	23	rin	rin	PROPN
bionys-641	182	24	e/	e/	ADV
bionys-641	182	25	th	th	X
bionys-641	182	26	re	re	VERB
bionys-641	182	27	on	on	ADP
bionys-641	182	28	in	in	ADP
bionys-641	182	29	epr	epr	PROPN
bionys-641	182	30	ot	ot	INTJ
bionys-641	182	31	ei	ei	PROPN
bionys-641	182	32	n	n	ADV
bionys-641	182	33	ki	ki	INTJ
bionys-641	182	34	na	na	INTJ
bionys-641	182	35	se	se	PROPN
bionys-641	182	36	1	1	NUM
bionys-641	182	37	,	,	PUNCT
bionys-641	182	38	r	r	NOUN
bionys-641	182	39	ip	ip	NOUN
bionys-641	182	40	k	k	NOUN
bionys-641	182	41	3	3	NUM
bionys-641	182	42	:	:	PUNCT
bionys-641	182	43	r	r	NOUN
bionys-641	182	44	ec	ec	PROPN
bionys-641	182	45	ep	ep	PROPN
bionys-641	182	46	to	to	ADP
bionys-641	182	47	r	r	VERB
bionys-641	182	48	-	-	PUNCT
bionys-641	182	49	i	i	PRON
bionys-641	182	50	nt	not	PART
bionys-641	182	51	er	er	INTJ
bionys-641	182	52	ac	ac	PROPN
bionys-641	182	53	tin	tin	PROPN
bionys-641	182	54	g	g	PROPN
bionys-641	182	55	se	se	PROPN
bionys-641	182	56	rin	rin	PROPN
bionys-641	182	57	e/	e/	ADV
bionys-641	182	58	th	th	X
bionys-641	182	59	re	re	VERB
bionys-641	182	60	on	on	ADP
bionys-641	182	61	in	in	ADP
bionys-641	182	62	epr	epr	PROPN
bionys-641	182	63	ot	ot	INTJ
bionys-641	182	64	ei	ei	PROPN
bionys-641	182	65	n	n	ADV
bionys-641	182	66	ki	ki	INTJ
bionys-641	182	67	na	na	INTJ
bionys-641	182	68	se	se	PROPN
bionys-641	182	69	3	3	NUM
bionys-641	182	70	,	,	PUNCT
bionys-641	182	71	r	r	NOUN
bionys-641	182	72	sl	sl	PROPN
bionys-641	182	73	3	3	NUM
bionys-641	182	74	:	:	PUNCT
bionys-641	182	75	r	r	NOUN
bionys-641	182	76	as	as	ADP
bionys-641	182	77	se	se	X
bionys-641	182	78	le	le	X
bionys-641	182	79	ct	ct	PROPN
bionys-641	182	80	iv	iv	NUM
bionys-641	182	81	e	e	X
bionys-641	182	82	le	le	X
bionys-641	182	83	th	th	PROPN
bionys-641	182	84	al	al	PROPN
bionys-641	182	85	3	3	NUM
bionys-641	182	86	,	,	PUNCT
bionys-641	182	87	t	t	PROPN
bionys-641	182	88	n	n	PROPN
bionys-641	182	89	f	f	NOUN
bionys-641	182	90	:	:	PUNCT
bionys-641	182	91	t	t	PROPN
bionys-641	182	92	um	um	INTJ
bionys-641	182	93	or	or	CCONJ
bionys-641	182	94	n	n	CCONJ
bionys-641	182	95	ec	ec	PROPN
bionys-641	182	96	ro	ro	NOUN
bionys-641	183	1	si	si	PROPN
bionys-641	183	2	s	s	X
bionys-641	183	3	fa	fa	INTJ
bionys-641	183	4	ct	ct	NOUN
bionys-641	183	5	or	or	CCONJ
bionys-641	183	6	fe	fe	NOUN
bionys-641	183	7	at	at	ADP
bionys-641	183	8	ur	ur	PROPN
bionys-641	183	9	e	e	PROPN
bionys-641	183	10	a	a	DET
bionys-641	183	11	po	po	INTJ
bionys-641	184	1	pt	pt	X
bionys-641	184	2	os	os	NOUN
bionys-641	184	3	is	be	AUX
bionys-641	184	4	n	n	PRON
bionys-641	184	5	ec	ec	PROPN
bionys-641	184	6	ro	ro	X
bionys-641	184	7	pt	pt	PROPN
bionys-641	184	8	os	os	PROPN
bionys-641	184	9	is	be	AUX
bionys-641	184	10	fe	fe	X
bionys-641	184	11	rr	rr	NOUN
bionys-641	184	12	op	op	NOUN
bionys-641	184	13	to	to	ADP
bionys-641	184	14	si	si	PROPN
bionys-641	184	15	s	s	PROPN
bionys-641	184	16	a	a	DET
bionys-641	184	17	ut	ut	PROPN
bionys-641	184	18	op	op	NOUN
bionys-641	185	1	ha	ha	INTJ
bionys-641	185	2	gy	gy	INTJ
bionys-641	185	3	py	py	PROPN
bionys-641	185	4	ro	ro	PROPN
bionys-641	185	5	pt	pt	PROPN
bionys-641	185	6	os	os	PROPN
bionys-641	185	7	is	be	AUX
bionys-641	185	8	k	k	PROPN
bionys-641	185	9	ey	ey	PROPN
bionys-641	185	10	m	m	PROPN
bionys-641	185	11	ed	ed	PROPN
bionys-641	185	12	ia	ia	PROPN
bionys-641	185	13	to	to	ADP
bionys-641	185	14	rs	rs	PROPN
bionys-641	185	15	c	c	PROPN
bionys-641	185	16	as	as	SCONJ
bionys-641	185	17	pa	pa	PROPN
bionys-641	185	18	se	se	PROPN
bionys-641	185	19	s	s	PROPN
bionys-641	185	20	(	(	PUNCT
bionys-641	185	21	in	in	ADP
bionys-641	185	22	iti	iti	PROPN
bionys-641	185	23	at	at	ADP
bionys-641	185	24	or	or	CCONJ
bionys-641	185	25	:	:	PUNCT
bionys-641	185	26	8	8	NUM
bionys-641	185	27	,	,	PUNCT
bionys-641	185	28	9	9	NUM
bionys-641	185	29	;	;	PUNCT
bionys-641	185	30	e	e	PROPN
bionys-641	185	31	xe	xe	PROPN
bionys-641	185	32	cu	cu	PROPN
bionys-641	185	33	tio	tio	NOUN
bionys-641	185	34	ne	ne	X
bionys-641	185	35	r	r	NOUN
bionys-641	185	36	:	:	PUNCT
bionys-641	185	37	3	3	NUM
bionys-641	185	38	,	,	PUNCT
bionys-641	185	39	6	6	NUM
bionys-641	185	40	,	,	PUNCT
bionys-641	185	41	7	7	NUM
bionys-641	185	42	)	)	PUNCT
bionys-641	185	43	,	,	PUNCT
bionys-641	185	44	b	b	X
bionys-641	185	45	c	c	NOUN
bionys-641	185	46	l2	l2	NOUN
bionys-641	185	47	fa	fa	INTJ
bionys-641	185	48	m	m	VERB
bionys-641	185	49	ily	ily	ADV
bionys-641	185	50	,	,	PUNCT
bionys-641	185	51	a	a	DET
bionys-641	185	52	pa	pa	PROPN
bionys-641	185	53	f1	f1	PROPN
bionys-641	185	54	r	r	NOUN
bionys-641	185	55	ip	ip	NOUN
bionys-641	185	56	k	k	NOUN
bionys-641	185	57	1	1	NUM
bionys-641	185	58	,	,	PUNCT
bionys-641	185	59	r	r	NOUN
bionys-641	185	60	ip	ip	NOUN
bionys-641	185	61	k	k	NOUN
bionys-641	185	62	3	3	NUM
bionys-641	185	63	,	,	PUNCT
bionys-641	185	64	m	m	VERB
bionys-641	185	65	lk	lk	PROPN
bionys-641	185	66	l	l	PROPN
bionys-641	185	67	ir	ir	X
bionys-641	185	68	on	on	ADV
bionys-641	185	69	,	,	PUNCT
bionys-641	185	70	a	a	DET
bionys-641	185	71	c	c	NOUN
bionys-641	185	72	sl	sl	NOUN
bionys-641	185	73	4	4	NUM
bionys-641	185	74	,	,	PUNCT
bionys-641	185	75	g	g	PROPN
bionys-641	185	76	px	px	PROPN
bionys-641	185	77	4	4	NUM
bionys-641	185	78	,	,	PUNCT
bionys-641	185	79	pu	pu	PROPN
bionys-641	185	80	fa	fa	PROPN
bionys-641	186	1	s	s	PROPN
bionys-641	186	2	a	a	DET
bionys-641	186	3	tg	tg	X
bionys-641	186	4	p	p	X
bionys-641	186	5	ro	ro	X
bionys-641	186	6	te	te	NOUN
bionys-641	186	7	in	in	ADP
bionys-641	186	8	s	s	PROPN
bionys-641	186	9	:	:	PUNCT
bionys-641	186	10	a	a	DET
bionys-641	186	11	tg	tg	PROPN
bionys-641	186	12	5	5	NUM
bionys-641	186	13	,	,	PUNCT
bionys-641	186	14	a	a	DET
bionys-641	186	15	tg	tg	PROPN
bionys-641	186	16	7	7	NUM
bionys-641	186	17	,	,	PUNCT
bionys-641	186	18	a	a	DET
bionys-641	186	19	tg	tg	PROPN
bionys-641	186	20	12	12	NUM
bionys-641	186	21	,	,	PUNCT
bionys-641	186	22	a	a	DET
bionys-641	186	23	nd	nd	NOUN
bionys-641	186	24	a	a	DET
bionys-641	186	25	tg	tg	PROPN
bionys-641	186	26	8	8	NUM
bionys-641	186	27	g	g	NOUN
bionys-641	186	28	as	as	ADP
bionys-641	186	29	de	de	PROPN
bionys-641	186	30	rm	rm	PROPN
bionys-641	186	31	in	in	ADP
bionys-641	186	32	s	s	PROPN
bionys-641	186	33	(	(	PUNCT
bionys-641	186	34	g	g	PROPN
bionys-641	186	35	sd	sd	NOUN
bionys-641	186	36	m	m	PROPN
bionys-641	186	37	d	d	NOUN
bionys-641	186	38	,	,	PUNCT
bionys-641	186	39	g	g	PROPN
bionys-641	186	40	sd	sd	NOUN
bionys-641	186	41	m	m	NOUN
bionys-641	186	42	e	e	NOUN
bionys-641	186	43	)	)	PUNCT
bionys-641	186	44	,	,	PUNCT
bionys-641	186	45	c	c	PROPN
bionys-641	186	46	as	as	SCONJ
bionys-641	186	47	pa	pa	PROPN
bionys-641	186	48	se	se	PROPN
bionys-641	186	49	s	s	PROPN
bionys-641	186	50	(	(	PUNCT
bionys-641	186	51	1	1	NUM
bionys-641	186	52	,	,	PUNCT
bionys-641	186	53	4	4	NUM
bionys-641	186	54	,	,	PUNCT
bionys-641	186	55	5	5	NUM
bionys-641	186	56	,	,	PUNCT
bionys-641	186	57	1	1	NUM
bionys-641	186	58	1	1	NUM
bionys-641	186	59	)	)	PUNCT
bionys-641	186	60	,	,	PUNCT
bionys-641	186	61	i	i	PRON
bionys-641	186	62	nfl	nfl	PROPN
bionys-641	186	63	am	be	AUX
bionys-641	186	64	m	m	VERB
bionys-641	186	65	as	as	ADP
bionys-641	186	66	om	om	PROPN
bionys-641	186	67	es	es	ADP
bionys-641	186	68	m	m	PROPN
bionys-641	186	69	or	or	CCONJ
bionys-641	186	70	ph	ph	ADJ
bionys-641	186	71	ol	ol	PROPN
bionys-641	186	72	og	og	INTJ
bionys-641	186	73	y	y	PROPN
bionys-641	186	74	c	c	PROPN
bionys-641	186	75	el	el	PROPN
bionys-641	186	76	l	l	PROPN
bionys-641	186	77	s	s	PART
bionys-641	186	78	hr	hr	NOUN
bionys-641	186	79	in	in	ADP
bionys-641	186	80	ka	ka	PROPN
bionys-641	186	81	ge	ge	PROPN
bionys-641	186	82	,	,	PUNCT
bionys-641	187	1	ch	ch	PROPN
bionys-641	187	2	ro	ro	X
bionys-641	187	3	m	m	VERB
bionys-641	187	4	at	at	ADP
bionys-641	187	5	in	in	ADP
bionys-641	187	6	c	c	PROPN
bionys-641	187	7	on	on	ADP
bionys-641	187	8	de	de	X
bionys-641	187	9	ns	ns	NUM
bionys-641	187	10	at	at	ADP
bionys-641	187	11	io	io	PROPN
bionys-641	187	12	n	n	CCONJ
bionys-641	187	13	,	,	PUNCT
bionys-641	187	14	m	m	VERB
bionys-641	187	15	em	em	PRON
bionys-641	187	16	br	br	VERB
bionys-641	187	17	an	an	DET
bionys-641	187	18	e	e	NOUN
bionys-641	187	19	bl	bl	PROPN
bionys-641	187	20	eb	eb	PROPN
bionys-641	187	21	bi	bi	PROPN
bionys-641	187	22	ng	ng	PROPN
bionys-641	187	23	,	,	PUNCT
bionys-641	187	24	ap	ap	PROPN
bionys-641	187	25	op	op	NOUN
bionys-641	187	26	to	to	ADP
bionys-641	187	27	tic	tic	PROPN
bionys-641	187	28	b	b	PROPN
bionys-641	187	29	od	od	ADP
bionys-641	187	30	ie	ie	PROPN
bionys-641	187	31	s	s	PROPN
bionys-641	187	32	c	c	PROPN
bionys-641	187	33	el	el	PROPN
bionys-641	187	34	l	l	PROPN
bionys-641	187	35	s	s	PROPN
bionys-641	187	36	w	w	PROPN
bionys-641	187	37	el	el	PROPN
bionys-641	187	38	lin	lin	PROPN
bionys-641	187	39	g	g	PROPN
bionys-641	187	40	(	(	PUNCT
bionys-641	187	41	o	o	PROPN
bionys-641	187	42	nc	nc	PROPN
bionys-641	187	43	os	os	PROPN
bionys-641	187	44	is	be	AUX
bionys-641	187	45	)	)	PUNCT
bionys-641	187	46	,	,	PUNCT
bionys-641	187	47	m	m	VERB
bionys-641	187	48	em	em	PRON
bionys-641	187	49	br	br	VERB
bionys-641	187	50	an	an	DET
bionys-641	187	51	e	e	PROPN
bionys-641	187	52	ru	ru	PROPN
bionys-641	187	53	pt	pt	PROPN
bionys-641	187	54	ur	ur	PROPN
bionys-641	187	55	e	e	PROPN
bionys-641	187	56	,	,	PUNCT
bionys-641	187	57	or	or	CCONJ
bionys-641	188	1	ga	ga	PROPN
bionys-641	188	2	ne	ne	PROPN
bionys-641	188	3	lle	lle	PROPN
bionys-641	188	4	sw	sw	PROPN
bionys-641	188	5	el	el	PROPN
bionys-641	188	6	lin	lin	PROPN
bionys-641	188	7	g	g	PROPN
bionys-641	188	8	m	m	PROPN
bionys-641	188	9	ito	ito	PROPN
bionys-641	188	10	ch	ch	PROPN
bionys-641	188	11	on	on	ADP
bionys-641	188	12	dr	dr	PROPN
bionys-641	188	13	ia	ia	PROPN
bionys-641	188	14	l	l	PROPN
bionys-641	188	15	sh	sh	PROPN
bionys-641	188	16	rin	rin	PROPN
bionys-641	188	17	ka	ka	PROPN
bionys-641	188	18	ge	ge	PROPN
bionys-641	188	19	,	,	PUNCT
bionys-641	188	20	i	i	PRON
bionys-641	188	21	nc	nc	PROPN
bionys-641	188	22	re	re	PROPN
bionys-641	188	23	as	as	ADP
bionys-641	188	24	ed	ed	PROPN
bionys-641	188	25	m	m	VERB
bionys-641	188	26	em	em	PRON
bionys-641	188	27	br	br	VERB
bionys-641	188	28	an	an	DET
bionys-641	188	29	e	e	X
bionys-641	188	30	de	de	X
bionys-641	188	31	ns	ns	PROPN
bionys-641	188	32	ity	ity	PROPN
bionys-641	188	33	,	,	PUNCT
bionys-641	188	34	in	in	ADP
bionys-641	188	35	ta	ta	ADP
bionys-641	188	36	ct	ct	NUM
bionys-641	188	37	n	n	PROPN
bionys-641	188	38	uc	uc	INTJ
bionys-641	188	39	le	le	VERB
bionys-641	188	40	us	us	PROPN
bionys-641	188	41	fo	fo	INTJ
bionys-641	188	42	rm	rm	PROPN
bionys-641	188	43	at	at	ADP
bionys-641	188	44	io	io	PROPN
bionys-641	188	45	n	n	PROPN
bionys-641	188	46	of	of	ADP
bionys-641	188	47	a	a	DET
bionys-641	188	48	d	d	X
bionys-641	188	49	ou	ou	NOUN
bionys-641	188	50	bl	bl	INTJ
bionys-641	188	51	em	em	PRON
bionys-641	188	52	em	em	PRON
bionys-641	188	53	br	br	VERB
bionys-641	188	54	an	an	DET
bionys-641	188	55	e	e	X
bionys-641	188	56	ve	ve	NOUN
bionys-641	188	57	si	si	X
bionys-641	188	58	cl	cl	PROPN
bionys-641	188	59	e	e	X
bionys-641	188	60	(	(	PUNCT
bionys-641	188	61	a	a	DET
bionys-641	188	62	ut	ut	PROPN
bionys-641	188	63	op	op	NOUN
bionys-641	188	64	ha	ha	INTJ
bionys-641	188	65	go	go	VERB
bionys-641	188	66	so	so	ADV
bionys-641	188	67	m	m	ADV
bionys-641	188	68	e	e	NOUN
bionys-641	188	69	)	)	PUNCT
bionys-641	189	1	c	c	PROPN
bionys-641	189	2	el	el	PROPN
bionys-641	189	3	l	l	PROPN
bionys-641	189	4	s	s	PROPN
bionys-641	189	5	w	w	PROPN
bionys-641	189	6	el	el	PROPN
bionys-641	189	7	lin	lin	PROPN
bionys-641	189	8	g	g	PROPN
bionys-641	189	9	,	,	PUNCT
bionys-641	189	10	m	m	VERB
bionys-641	189	11	em	em	PRON
bionys-641	189	12	br	br	VERB
bionys-641	189	13	an	an	DET
bionys-641	189	14	e	e	PROPN
bionys-641	189	15	ru	ru	PROPN
bionys-641	189	16	pt	pt	PROPN
bionys-641	189	17	ur	ur	PROPN
bionys-641	189	18	e	e	PROPN
bionys-641	189	19	,	,	PUNCT
bionys-641	189	20	p	p	NOUN
bionys-641	189	21	or	or	CCONJ
bionys-641	189	22	e	e	NOUN
bionys-641	189	23	fo	fo	ADP
bionys-641	189	24	rm	rm	PROPN
bionys-641	189	25	at	at	ADP
bionys-641	189	26	io	io	PROPN
bionys-641	189	27	n	n	CCONJ
bionys-641	189	28	,	,	PUNCT
bionys-641	189	29	„	„	PUNCT
bionys-641	189	30	p	p	NOUN
bionys-641	189	31	yr	yr	NOUN
bionys-641	189	32	op	op	NOUN
bionys-641	189	33	to	to	ADP
bionys-641	189	34	tic	tic	PROPN
bionys-641	189	35	b	b	PROPN
bionys-641	189	36	od	od	PROPN
bionys-641	189	37	ie	ie	PROPN
bionys-641	189	38	s	s	PART
bionys-641	189	39	”	"	PUNCT
bionys-641	189	40	pr	pr	NOUN
bionys-641	189	41	i	i	PROPN
bionys-641	189	42	m	m	PROPN
bionys-641	189	43	ar	ar	PROPN
bionys-641	189	44	y	y	PROPN
bionys-641	189	45	t	t	PROPN
bionys-641	190	1	ri	ri	PROPN
bionys-641	190	2	gg	gg	PROPN
bionys-641	190	3	er	er	INTJ
bionys-641	190	4	s	s	PROPN
bionys-641	190	5	d	d	PROPN
bionys-641	190	6	n	n	ADP
bionys-641	190	7	a	a	PRON
bionys-641	190	8	d	d	NOUN
bionys-641	190	9	am	be	AUX
bionys-641	190	10	ag	ag	PROPN
bionys-641	190	11	e	e	PROPN
bionys-641	190	12	,	,	PUNCT
bionys-641	191	1	g	g	PROPN
bionys-641	191	2	ro	ro	PROPN
bionys-641	191	3	w	w	PROPN
bionys-641	191	4	th	th	INTJ
bionys-641	191	5	fa	fa	NOUN
bionys-641	191	6	ct	ct	INTJ
bionys-641	191	7	or	or	CCONJ
bionys-641	191	8	w	w	PROPN
bionys-641	191	9	ith	ith	PROPN
bionys-641	191	10	dr	dr	PROPN
bionys-641	192	1	aw	aw	INTJ
bionys-641	192	2	al	al	PROPN
bionys-641	192	3	,	,	PUNCT
bionys-641	192	4	d	d	PROPN
bionys-641	192	5	ea	ea	X
bionys-641	192	6	th	th	X
bionys-641	192	7	re	re	X
bionys-641	192	8	ce	ce	PROPN
bionys-641	192	9	pt	pt	PROPN
bionys-641	192	10	or	or	CCONJ
bionys-641	192	11	li	li	PROPN
bionys-641	192	12	ga	ga	PROPN
bionys-641	192	13	tio	tio	PROPN
bionys-641	192	14	n	n	PROPN
bionys-641	192	15	(	(	PUNCT
bionys-641	192	16	t	t	PROPN
bionys-641	192	17	n	n	CCONJ
bionys-641	192	18	f	f	NOUN
bionys-641	192	19	,	,	PUNCT
bionys-641	192	20	fa	fa	INTJ
bionys-641	192	21	sl	sl	INTJ
bionys-641	192	22	)	)	PUNCT
bionys-641	193	1	d	d	SYM
bionys-641	193	2	ea	ea	X
bionys-641	193	3	th	th	X
bionys-641	193	4	re	re	X
bionys-641	193	5	ce	ce	PROPN
bionys-641	193	6	pt	pt	PROPN
bionys-641	193	7	or	or	CCONJ
bionys-641	193	8	lig	lig	PROPN
bionys-641	193	9	at	at	ADP
bionys-641	193	10	io	io	PROPN
bionys-641	193	11	n+	n+	PRON
bionys-641	193	12	ca	can	AUX
bionys-641	193	13	sp	sp	VERB
bionys-641	193	14	as	as	ADP
bionys-641	193	15	e	e	PROPN
bionys-641	193	16	in	in	ADP
bionys-641	193	17	hi	hi	INTJ
bionys-641	193	18	bi	bi	PROPN
bionys-641	193	19	tio	tio	PROPN
bionys-641	193	20	n	n	CCONJ
bionys-641	193	21	,	,	PUNCT
bionys-641	194	1	p	p	X
bionys-641	194	2	a	a	DET
bionys-641	194	3	m	m	NOUN
bionys-641	194	4	ps	ps	PROPN
bionys-641	194	5	/	/	SYM
bionys-641	194	6	d	d	PROPN
bionys-641	194	7	a	a	DET
bionys-641	194	8	m	m	NOUN
bionys-641	194	9	ps	ps	NOUN
bionys-641	194	10	,	,	PUNCT
bionys-641	194	11	v	v	ADP
bionys-641	195	1	ira	ira	PROPN
bionys-641	195	2	l	l	NOUN
bionys-641	196	1	i	i	PRON
bionys-641	196	2	nf	nf	VERB
bionys-641	196	3	ec	ec	PROPN
bionys-641	196	4	tio	tio	NOUN
bionys-641	196	5	n	n	ADV
bionys-641	197	1	g	g	NOUN
bionys-641	197	2	lu	lu	NOUN
bionys-641	197	3	ta	ta	X
bionys-641	197	4	m	m	VERB
bionys-641	197	5	at	at	ADP
bionys-641	197	6	e	e	NOUN
bionys-641	197	7	,	,	PUNCT
bionys-641	197	8	g	g	PROPN
bionys-641	197	9	px	px	PROPN
bionys-641	197	10	4	4	NUM
bionys-641	197	11	in	in	ADP
bionys-641	197	12	hi	hi	INTJ
bionys-641	197	13	bi	bi	PROPN
bionys-641	197	14	tio	tio	PROPN
bionys-641	197	15	n	n	CCONJ
bionys-641	197	16	,	,	PUNCT
bionys-641	197	17	ir	ir	PROPN
bionys-641	197	18	on	on	ADP
bionys-641	197	19	ov	ov	INTJ
bionys-641	197	20	er	er	INTJ
bionys-641	197	21	lo	lo	PROPN
bionys-641	197	22	ad	ad	NOUN
bionys-641	197	23	,	,	PUNCT
bionys-641	197	24	o	o	X
bionys-641	197	25	xi	xi	X
bionys-641	197	26	da	da	PROPN
bionys-641	197	27	tiv	tiv	PROPN
bionys-641	197	28	e	e	PROPN
bionys-641	197	29	st	st	PROPN
bionys-641	198	1	re	re	VERB
bionys-641	198	2	ss	ss	PROPN
bionys-641	198	3	c	c	PROPN
bionys-641	199	1	el	el	PROPN
bionys-641	199	2	lu	lu	PROPN
bionys-641	200	1	la	la	PROPN
bionys-641	201	1	r	r	NOUN
bionys-641	201	2	s	s	PROPN
bionys-641	201	3	ta	ta	X
bionys-641	201	4	rv	rv	PROPN
bionys-641	201	5	at	at	ADP
bionys-641	201	6	io	io	PROPN
bionys-641	201	7	n	n	X
bionys-641	201	8	,	,	PUNCT
bionys-641	201	9	nu	nu	PROPN
bionys-641	201	10	tri	tri	PROPN
bionys-641	201	11	en	en	PROPN
bionys-641	201	12	t	t	PROPN
bionys-641	201	13	a	a	DET
bionys-641	201	14	nd	nd	NOUN
bionys-641	201	15	g	g	PROPN
bionys-641	201	16	ro	ro	PROPN
bionys-641	201	17	w	w	X
bionys-641	201	18	th	th	INTJ
bionys-641	201	19	fa	fa	NOUN
bionys-641	202	1	ct	ct	INTJ
bionys-641	202	2	or	or	CCONJ
bionys-641	202	3	d	d	PROPN
bionys-641	202	4	ep	ep	PROPN
bionys-641	202	5	riv	riv	PROPN
bionys-641	202	6	at	at	ADP
bionys-641	202	7	io	io	PROPN
bionys-641	202	8	n	n	CCONJ
bionys-641	202	9	,	,	PUNCT
bionys-641	202	10	ce	ce	PROPN
bionys-641	202	11	llu	llu	X
bionys-641	203	1	la	la	PROPN
bionys-641	203	2	r	r	NOUN
bionys-641	203	3	s	s	PROPN
bionys-641	203	4	tre	tre	PROPN
bionys-641	203	5	ss	ss	PROPN
bionys-641	203	6	a	a	DET
bionys-641	203	7	nd	nd	NOUN
bionys-641	203	8	or	or	CCONJ
bionys-641	203	9	ga	ga	PROPN
bionys-641	203	10	ne	ne	PROPN
bionys-641	203	11	lle	lle	PROPN
bionys-641	203	12	d	d	PROPN
bionys-641	203	13	am	be	AUX
bionys-641	203	14	ag	ag	PROPN
bionys-641	203	15	e	e	PROPN
bionys-641	203	16	pa	pa	PROPN
bionys-641	203	17	m	m	PROPN
bionys-641	203	18	ps	ps	PROPN
bionys-641	203	19	/d	/d	INTJ
bionys-641	203	20	a	a	DET
bionys-641	203	21	m	m	NOUN
bionys-641	203	22	ps	ps	NOUN
bionys-641	203	23	(	(	PUNCT
bionys-641	203	24	e	e	NOUN
bionys-641	203	25	.g	.g	PROPN
bionys-641	203	26	.	.	PUNCT
bionys-641	204	1	,	,	PUNCT
bionys-641	204	2	lp	lp	PROPN
bionys-641	204	3	s	s	NOUN
bionys-641	204	4	)	)	PUNCT
bionys-641	204	5	,	,	PUNCT
bionys-641	205	1	p	p	X
bionys-641	205	2	at	at	ADP
bionys-641	205	3	ho	ho	PROPN
bionys-641	205	4	ge	ge	PROPN
bionys-641	205	5	n	n	PROPN
bionys-641	205	6	in	in	ADP
bionys-641	205	7	fe	fe	X
bionys-641	205	8	ct	ct	PROPN
bionys-641	205	9	io	io	PROPN
bionys-641	205	10	n	n	PROPN
bionys-641	205	11	,	,	PUNCT
bionys-641	205	12	ch	ch	PROPN
bionys-641	205	13	em	em	PRON
bionys-641	205	14	ot	ot	INTJ
bionys-641	205	15	he	he	PRON
bionys-641	205	16	ra	ra	INTJ
bionys-641	206	1	py	py	INTJ
bionys-641	206	2	i	i	PRON
bionys-641	206	3	m	m	VERB
bionys-641	206	4	m	m	VERB
bionys-641	207	1	un	un	PROPN
bionys-641	207	2	ol	ol	PROPN
bionys-641	207	3	og	og	PROPN
bionys-641	207	4	ic	ic	PROPN
bionys-641	207	5	al	al	PROPN
bionys-641	207	6	c	c	PROPN
bionys-641	207	7	on	on	ADP
bionys-641	207	8	se	se	X
bionys-641	207	9	qu	qu	PROPN
bionys-641	207	10	en	en	PROPN
bionys-641	207	11	ce	ce	PROPN
bionys-641	207	12	g	g	PROPN
bionys-641	207	13	en	en	PROPN
bionys-641	207	14	er	er	INTJ
bionys-641	207	15	al	al	PROPN
bionys-641	207	16	ly	ly	PROPN
bionys-641	207	17	n	n	CCONJ
bionys-641	207	18	on	on	ADV
bionys-641	207	19	in	in	ADP
bionys-641	207	20	fla	fla	PROPN
bionys-641	207	21	m	m	NOUN
bionys-641	207	22	m	m	VERB
bionys-641	207	23	at	at	ADP
bionys-641	207	24	or	or	CCONJ
bionys-641	207	25	y	y	PROPN
bionys-641	207	26	(	(	PUNCT
bionys-641	207	27	„	„	PUNCT
bionys-641	207	28	si	si	PROPN
bionys-641	207	29	le	le	X
bionys-641	207	30	nt	not	PART
bionys-641	207	31	”	"	PUNCT
bionys-641	207	32	)	)	PUNCT
bionys-641	207	33	h	h	NOUN
bionys-641	208	1	ig	ig	PROPN
bionys-641	208	2	hl	hl	PROPN
bionys-641	208	3	y	y	PROPN
bionys-641	208	4	in	in	ADP
bionys-641	208	5	fla	fla	PROPN
bionys-641	208	6	m	m	VERB
bionys-641	208	7	m	m	VERB
bionys-641	208	8	at	at	ADP
bionys-641	208	9	or	or	CCONJ
bionys-641	208	10	y	y	PROPN
bionys-641	208	11	(	(	PUNCT
bionys-641	208	12	d	d	PROPN
bionys-641	208	13	a	a	DET
bionys-641	208	14	m	m	NOUN
bionys-641	208	15	p	p	X
bionys-641	208	16	re	re	ADP
bionys-641	208	17	le	le	X
bionys-641	208	18	as	as	ADP
bionys-641	208	19	e	e	NOUN
bionys-641	208	20	)	)	PUNCT
bionys-641	208	21	c	c	PROPN
bionys-641	208	22	on	on	ADP
bionys-641	208	23	te	te	PROPN
bionys-641	208	24	xt	xt	PROPN
bionys-641	208	25	-d	-d	PRON
bionys-641	208	26	ep	ep	PROPN
bionys-641	208	27	en	en	PROPN
bionys-641	208	28	de	de	X
bionys-641	208	29	nt	not	PART
bionys-641	208	30	,	,	PUNCT
bionys-641	208	31	c	c	X
bionys-641	208	32	an	an	DET
bionys-641	208	33	be	be	AUX
bionys-641	208	34	i	i	PROPN
bionys-641	208	35	m	m	NOUN
bionys-641	208	36	m	m	VERB
bionys-641	208	37	un	un	PROPN
bionys-641	208	38	og	og	PROPN
bionys-641	208	39	en	en	PROPN
bionys-641	208	40	ic	ic	PROPN
bionys-641	208	41	c	c	PROPN
bionys-641	208	42	on	on	ADP
bionys-641	208	43	te	te	PROPN
bionys-641	208	44	xt	xt	PROPN
bionys-641	208	45	-d	-d	DET
bionys-641	208	46	ep	ep	PROPN
bionys-641	208	47	en	en	PROPN
bionys-641	208	48	de	de	PROPN
bionys-641	208	49	nt	nt	PROPN
bionys-641	208	50	h	h	NOUN
bionys-641	209	1	ig	ig	INTJ
bionys-641	209	2	hl	hl	PROPN
bionys-641	209	3	y	y	PROPN
bionys-641	209	4	in	in	ADP
bionys-641	209	5	fla	fla	PROPN
bionys-641	209	6	m	m	VERB
bionys-641	209	7	m	m	VERB
bionys-641	209	8	at	at	ADP
bionys-641	209	9	or	or	CCONJ
bionys-641	209	10	y	y	PROPN
bionys-641	209	11	(	(	PUNCT
bionys-641	209	12	i	i	PRON
bionys-641	209	13	l1β	l1β	X
bionys-641	209	14	/il	/il	PUNCT
bionys-641	209	15	-1	-1	X
bionys-641	209	16	8	8	NUM
bionys-641	209	17	re	re	VERB
bionys-641	209	18	le	le	X
bionys-641	209	19	as	as	ADP
bionys-641	209	20	e	e	NOUN
bionys-641	209	21	)	)	PUNCT
bionys-641	209	22	k	k	PROPN
bionys-641	210	1	ey	ey	INTJ
bionys-641	210	2	p	p	X
bionys-641	210	3	ha	ha	INTJ
bionys-641	210	4	rm	rm	PROPN
bionys-641	210	5	ac	ac	PROPN
bionys-641	211	1	ol	ol	PROPN
bionys-641	212	1	og	og	PROPN
bionys-641	213	1	ic	ic	PROPN
bionys-641	214	1	al	al	PROPN
bionys-641	214	2	m	m	PROPN
bionys-641	214	3	od	od	PROPN
bionys-641	214	4	ul	ul	INTJ
bionys-641	214	5	at	at	ADP
bionys-641	214	6	or	or	CCONJ
bionys-641	214	7	s	s	PROPN
bionys-641	214	8	in	in	ADP
bionys-641	214	9	du	du	PROPN
bionys-641	214	10	ce	ce	PROPN
bionys-641	214	11	rs	rs	PROPN
bionys-641	214	12	:	:	PUNCT
bionys-641	215	1	b	b	X
bionys-641	215	2	h	h	NOUN
bionys-641	215	3	3	3	NUM
bionys-641	215	4	m	m	VERB
bionys-641	215	5	i	i	PRON
bionys-641	215	6	m	m	VERB
bionys-641	215	7	et	et	VERB
bionys-641	215	8	ic	ic	PROPN
bionys-641	215	9	s	s	PROPN
bionys-641	215	10	(	(	PUNCT
bionys-641	215	11	e.	e.	PROPN
bionys-641	215	12	g.	g.	PROPN
bionys-641	215	13	,	,	PUNCT
bionys-641	215	14	v	v	ADP
bionys-641	215	15	en	en	ADP
bionys-641	215	16	et	et	NOUN
bionys-641	215	17	oc	oc	X
bionys-641	215	18	la	la	PROPN
bionys-641	215	19	x	x	NOUN
bionys-641	215	20	)	)	PUNCT
bionys-641	215	21	.	.	PUNCT
bionys-641	216	1	in	in	ADP
bionys-641	216	2	hi	hi	INTJ
bionys-641	216	3	bi	bi	NOUN
bionys-641	216	4	to	to	PART
bionys-641	216	5	rs	rs	VERB
bionys-641	216	6	:	:	PUNCT
bionys-641	217	1	p	p	X
bionys-641	217	2	an	an	PRON
bionys-641	217	3	-c	-c	PUNCT
bionys-641	217	4	as	as	ADP
bionys-641	217	5	pa	pa	PROPN
bionys-641	217	6	se	se	PROPN
bionys-641	217	7	in	in	ADP
bionys-641	217	8	hi	hi	INTJ
bionys-641	217	9	bi	bi	NOUN
bionys-641	217	10	to	to	PART
bionys-641	217	11	rs	rs	VERB
bionys-641	217	12	(	(	PUNCT
bionys-641	217	13	e	e	NOUN
bionys-641	217	14	.g	.g	PROPN
bionys-641	217	15	.	.	PUNCT
bionys-641	217	16	,	,	PUNCT
bionys-641	217	17	zv	zv	PROPN
bionys-641	217	18	a	a	PRON
bionys-641	217	19	d	d	X
bionys-641	217	20	fm	fm	PROPN
bionys-641	217	21	k	k	NOUN
bionys-641	217	22	)	)	PUNCT
bionys-641	217	23	in	in	ADP
bionys-641	217	24	hi	hi	INTJ
bionys-641	217	25	bi	bi	NOUN
bionys-641	217	26	to	to	PART
bionys-641	217	27	rs	rs	VERB
bionys-641	217	28	:	:	PUNCT
bionys-641	217	29	r	r	NOUN
bionys-641	217	30	ip	ip	NOUN
bionys-641	217	31	k	k	NOUN
bionys-641	217	32	1	1	NUM
bionys-641	217	33	in	in	ADP
bionys-641	217	34	hi	hi	INTJ
bionys-641	217	35	bi	bi	NOUN
bionys-641	217	36	to	to	PART
bionys-641	217	37	rs	rs	VERB
bionys-641	217	38	(	(	PUNCT
bionys-641	217	39	e	e	NOUN
bionys-641	217	40	.g	.g	PROPN
bionys-641	217	41	.	.	PUNCT
bionys-641	218	1	,	,	PUNCT
bionys-641	218	2	n	n	PROPN
bionys-641	218	3	ec	ec	PROPN
bionys-641	218	4	ro	ro	PROPN
bionys-641	218	5	st	st	PROPN
bionys-641	219	1	at	at	ADP
bionys-641	219	2	in	in	ADP
bionys-641	219	3	-1	-1	PUNCT
bionys-641	219	4	,	,	PUNCT
bionys-641	219	5	g	g	PROPN
bionys-641	219	6	sk	sk	VERB
bionys-641	219	7	29	29	NUM
bionys-641	219	8	82	82	NUM
bionys-641	219	9	77	77	NUM
bionys-641	219	10	2	2	NUM
bionys-641	219	11	)	)	PUNCT
bionys-641	219	12	,	,	PUNCT
bionys-641	219	13	m	m	VERB
bionys-641	219	14	lk	lk	PROPN
bionys-641	219	15	l	l	PROPN
bionys-641	219	16	in	in	ADP
bionys-641	219	17	hi	hi	INTJ
bionys-641	219	18	bi	bi	NOUN
bionys-641	219	19	to	to	PART
bionys-641	219	20	rs	rs	VERB
bionys-641	219	21	(	(	PUNCT
bionys-641	219	22	e	e	NOUN
bionys-641	219	23	.g	.g	PROPN
bionys-641	219	24	.	.	PUNCT
bionys-641	220	1	,	,	PUNCT
bionys-641	220	2	n	n	PROPN
bionys-641	220	3	ec	ec	PROPN
bionys-641	220	4	ro	ro	PROPN
bionys-641	220	5	su	su	PROPN
bionys-641	220	6	lfo	lfo	PROPN
bionys-641	220	7	na	na	INTJ
bionys-641	220	8	m	m	PROPN
bionys-641	220	9	i	i	NOUN
bionys-641	220	10	d	d	PROPN
bionys-641	220	11	e	e	PROPN
bionys-641	220	12	)	)	PUNCT
bionys-641	220	13	in	in	ADP
bionys-641	220	14	du	du	PROPN
bionys-641	220	15	ce	ce	PROPN
bionys-641	220	16	rs	rs	PROPN
bionys-641	220	17	:	:	PUNCT
bionys-641	220	18	e	e	X
bionys-641	220	19	ra	ra	PROPN
bionys-641	220	20	st	st	PROPN
bionys-641	220	21	in	in	ADV
bionys-641	220	22	,	,	PUNCT
bionys-641	220	23	r	r	NOUN
bionys-641	220	24	sl	sl	PROPN
bionys-641	220	25	3	3	NUM
bionys-641	220	26	.	.	PUNCT
bionys-641	221	1	in	in	ADP
bionys-641	221	2	hi	hi	INTJ
bionys-641	221	3	bi	bi	NOUN
bionys-641	221	4	to	to	PART
bionys-641	221	5	rs	rs	VERB
bionys-641	221	6	:	:	PUNCT
bionys-641	221	7	fe	fe	X
bionys-641	221	8	rr	rr	X
bionys-641	221	9	os	os	NOUN
bionys-641	221	10	ta	ta	ADP
bionys-641	221	11	tin	tin	PROPN
bionys-641	221	12	-1	-1	NOUN
bionys-641	221	13	,	,	PUNCT
bionys-641	221	14	li	li	PROPN
bionys-641	221	15	pr	pr	PROPN
bionys-641	221	16	ox	ox	PROPN
bionys-641	221	17	st	st	PROPN
bionys-641	222	1	at	at	ADP
bionys-641	222	2	in	in	ADP
bionys-641	222	3	-1	-1	PUNCT
bionys-641	222	4	,	,	PUNCT
bionys-641	222	5	i	i	PRON
bionys-641	222	6	ro	ro	VERB
bionys-641	222	7	n	n	PROPN
bionys-641	222	8	ch	ch	PROPN
bionys-641	222	9	el	el	PROPN
bionys-641	222	10	at	at	ADP
bionys-641	222	11	or	or	CCONJ
bionys-641	222	12	s	s	PROPN
bionys-641	222	13	in	in	ADP
bionys-641	222	14	du	du	PROPN
bionys-641	222	15	ce	ce	PROPN
bionys-641	222	16	rs	rs	PROPN
bionys-641	222	17	:	:	PUNCT
bionys-641	222	18	m	m	AUX
bionys-641	222	19	to	to	ADP
bionys-641	222	20	r	r	VERB
bionys-641	222	21	in	in	ADP
bionys-641	222	22	hi	hi	INTJ
bionys-641	222	23	bi	bi	NOUN
bionys-641	222	24	to	to	ADP
bionys-641	222	25	r	r	PROPN
bionys-641	222	26	r	r	NOUN
bionys-641	222	27	ap	ap	PROPN
bionys-641	222	28	am	be	AUX
bionys-641	222	29	yc	yc	NOUN
bionys-641	222	30	in	in	ADP
bionys-641	222	31	an	an	DET
bionys-641	222	32	d	d	NOUN
bionys-641	222	33	its	its	PRON
bionys-641	222	34	d	d	X
bionys-641	222	35	er	er	INTJ
bionys-641	222	36	iv	iv	X
bionys-641	222	37	at	at	ADP
bionys-641	222	38	iv	iv	NOUN
bionys-641	222	39	es	es	NOUN
bionys-641	222	40	.	.	PUNCT
bionys-641	223	1	in	in	ADP
bionys-641	223	2	hi	hi	INTJ
bionys-641	223	3	bi	bi	NOUN
bionys-641	223	4	to	to	PART
bionys-641	223	5	rs	rs	VERB
bionys-641	223	6	:	:	PUNCT
bionys-641	223	7	c	c	X
bionys-641	223	8	hl	hl	NOUN
bionys-641	223	9	or	or	CCONJ
bionys-641	223	10	oq	oq	INTJ
bionys-641	223	11	ui	ui	PROPN
bionys-641	223	12	ne	ne	PROPN
bionys-641	224	1	a	a	DET
bionys-641	224	2	nd	nd	NOUN
bionys-641	224	3	h	h	NOUN
bionys-641	224	4	yd	yd	PROPN
bionys-641	224	5	ro	ro	PROPN
bionys-641	224	6	xy	xy	PROPN
bionys-641	224	7	ch	ch	PROPN
bionys-641	224	8	lo	lo	PROPN
bionys-641	224	9	ro	ro	X
bionys-641	224	10	qu	qu	PROPN
bionys-641	224	11	in	in	ADP
bionys-641	224	12	e	e	PROPN
bionys-641	224	13	in	in	ADP
bionys-641	224	14	hi	hi	INTJ
bionys-641	224	15	bi	bi	NOUN
bionys-641	224	16	to	to	PART
bionys-641	224	17	rs	rs	VERB
bionys-641	224	18	:	:	PUNCT
bionys-641	224	19	c	c	PROPN
bionys-641	224	20	as	as	ADP
bionys-641	224	21	pa	pa	PROPN
bionys-641	224	22	se	se	PROPN
bionys-641	224	23	-1	-1	PUNCT
bionys-641	224	24	in	in	ADP
bionys-641	224	25	hi	hi	INTJ
bionys-641	224	26	bi	bi	NOUN
bionys-641	224	27	to	to	PART
bionys-641	224	28	rs	rs	VERB
bionys-641	224	29	(	(	PUNCT
bionys-641	224	30	e	e	NOUN
bionys-641	224	31	.g	.g	PROPN
bionys-641	224	32	.	.	PUNCT
bionys-641	225	1	,	,	PUNCT
bionys-641	225	2	v	v	X
bionys-641	225	3	x	x	SYM
bionys-641	225	4	-7	-7	PROPN
bionys-641	225	5	65	65	NUM
bionys-641	225	6	)	)	PUNCT
bionys-641	225	7	,	,	PUNCT
bionys-641	225	8	g	g	PROPN
bionys-641	225	9	sd	sd	ADP
bionys-641	225	10	m	m	PROPN
bionys-641	225	11	d	d	NOUN
bionys-641	225	12	in	in	ADP
bionys-641	225	13	hi	hi	INTJ
bionys-641	225	14	bi	bi	NOUN
bionys-641	225	15	to	to	PART
bionys-641	225	16	rs	rs	VERB
bionys-641	225	17	the	the	DET
bionys-641	225	18	process	process	NOUN
bionys-641	225	19	is	be	AUX
bionys-641	225	20	triggered	trigger	VERB
bionys-641	225	21	by	by	ADP
bionys-641	225	22	oxidative	oxidative	ADJ
bionys-641	225	23	stress	stress	NOUN
bionys-641	225	24	,	,	PUNCT
bionys-641	225	25	resulting	result	VERB
bionys-641	225	26	in	in	ADP
bionys-641	225	27	dna	dna	PROPN
bionys-641	225	28	injury	injury	NOUN
bionys-641	225	29	and	and	CCONJ
bionys-641	225	30	chromatinolysis	chromatinolysi	NOUN
bionys-641	225	31	.	.	PUNCT
bionys-641	226	1	parthanotic	parthanotic	ADJ
bionys-641	226	2	cell	cell	NOUN
bionys-641	226	3	death	death	NOUN
bionys-641	226	4	does	do	AUX
bionys-641	226	5	not	not	PART
bionys-641	226	6	involve	involve	VERB
bionys-641	226	7	the	the	DET
bionys-641	226	8	generation	generation	NOUN
bionys-641	226	9	of	of	ADP
bionys-641	226	10	apoptotic	apoptotic	ADJ
bionys-641	226	11	bodies	body	NOUN
bionys-641	226	12	or	or	CCONJ
bionys-641	226	13	the	the	DET
bionys-641	226	14	breakdown	breakdown	NOUN
bionys-641	226	15	of	of	ADP
bionys-641	226	16	dna	dna	PROPN
bionys-641	226	17	.	.	PUNCT
bionys-641	227	1	furthermore	furthermore	ADV
bionys-641	227	2	,	,	PUNCT
bionys-641	227	3	there	there	PRON
bionys-641	227	4	is	be	VERB
bionys-641	227	5	no	no	DET
bionys-641	227	6	cell	cell	NOUN
bionys-641	227	7	swelling	swell	VERB
bionys-641	227	8	,	,	PUNCT
bionys-641	227	9	although	although	SCONJ
bionys-641	227	10	there	there	PRON
bionys-641	227	11	is	be	VERB
bionys-641	227	12	a	a	DET
bionys-641	227	13	rupture	rupture	NOUN
bionys-641	227	14	of	of	ADP
bionys-641	227	15	the	the	DET
bionys-641	227	16	plasma	plasma	NOUN
bionys-641	227	17	membrane	membrane	NOUN
bionys-641	227	18	(	(	PUNCT
bionys-641	227	19	andrabi	andrabi	NOUN
bionys-641	227	20	et	et	PROPN
bionys-641	227	21	al	al	PROPN
bionys-641	227	22	.	.	PROPN
bionys-641	227	23	,	,	PUNCT
bionys-641	227	24	2008	2008	NUM
bionys-641	227	25	)	)	PUNCT
bionys-641	227	26	.	.	PUNCT
bionys-641	228	1	parp1	parp1	PROPN
bionys-641	228	2	is	be	AUX
bionys-641	228	3	a	a	DET
bionys-641	228	4	chromatin	chromatin	NOUN
bionys-641	228	5	-	-	PUNCT
bionys-641	228	6	associated	associate	VERB
bionys-641	228	7	nuclear	nuclear	ADJ
bionys-641	228	8	protein	protein	NOUN
bionys-641	228	9	essential	essential	ADJ
bionys-641	228	10	for	for	ADP
bionys-641	228	11	singleand	singleand	NOUN
bionys-641	228	12	double	double	ADJ
bionys-641	228	13	-	-	PUNCT
bionys-641	228	14	strand	strand	NOUN
bionys-641	228	15	dna	dna	PROPN
bionys-641	228	16	repair	repair	NOUN
bionys-641	228	17	.	.	PUNCT
bionys-641	229	1	parp1	parp1	NOUN
bionys-641	229	2	detects	detect	NOUN
bionys-641	229	3	dna	dna	PROPN
bionys-641	229	4	damage	damage	NOUN
bionys-641	229	5	and	and	CCONJ
bionys-641	229	6	uses	use	VERB
bionys-641	229	7	nicotinamide	nicotinamide	NOUN
bionys-641	229	8	adenine	adenine	ADJ
bionys-641	229	9	dinucleotide	dinucleotide	NOUN
bionys-641	229	10	(	(	PUNCT
bionys-641	229	11	nad+	nad+	NOUN
bionys-641	229	12	)	)	PUNCT
bionys-641	229	13	and	and	CCONJ
bionys-641	229	14	atp	atp	NOUN
bionys-641	229	15	to	to	PART
bionys-641	229	16	initiate	initiate	VERB
bionys-641	229	17	poly(adp	poly(adp	NOUN
bionys-641	229	18	-	-	PUNCT
bionys-641	229	19	ribose)-ylation	ribose)-ylation	NOUN
bionys-641	229	20	(	(	PUNCT
bionys-641	229	21	vekariya	vekariya	NOUN
bionys-641	229	22	et	et	PROPN
bionys-641	229	23	al	al	PROPN
bionys-641	229	24	.	.	PROPN
bionys-641	229	25	,	,	PUNCT
bionys-641	229	26	2024	2024	NUM
bionys-641	229	27	)	)	PUNCT
bionys-641	229	28	.	.	PUNCT
bionys-641	230	1	the	the	DET
bionys-641	230	2	parthanatos	parthanato	NOUN
bionys-641	230	3	cycle	cycle	NOUN
bionys-641	230	4	necessitates	necessitate	VERB
bionys-641	230	5	the	the	DET
bionys-641	230	6	involvement	involvement	NOUN
bionys-641	230	7	of	of	ADP
bionys-641	230	8	the	the	DET
bionys-641	230	9	apoptotic	apoptotic	ADJ
bionys-641	230	10	dnase	dnase	NOUN
bionys-641	230	11	endonuclease	endonuclease	NOUN
bionys-641	230	12	g	g	NOUN
bionys-641	230	13	(	(	PUNCT
bionys-641	230	14	endog	endog	NOUN
bionys-641	230	15	)	)	PUNCT
bionys-641	230	16	and	and	CCONJ
bionys-641	230	17	the	the	DET
bionys-641	230	18	apoptosis	apoptosis	NOUN
bionys-641	230	19	-	-	PUNCT
bionys-641	230	20	inducing	induce	VERB
bionys-641	230	21	factor	factor	NOUN
bionys-641	230	22	mitochondriaassociated	mitochondriaassociate	VERB
bionys-641	230	23	1	1	NUM
bionys-641	230	24	(	(	PUNCT
bionys-641	230	25	aifm1	aifm1	PROPN
bionys-641	230	26	,	,	PUNCT
bionys-641	230	27	commonly	commonly	ADV
bionys-641	230	28	referred	refer	VERB
bionys-641	230	29	to	to	ADP
bionys-641	230	30	as	as	ADP
bionys-641	230	31	aif	aif	PROPN
bionys-641	230	32	)	)	PUNCT
bionys-641	230	33	.	.	PUNCT
bionys-641	231	1	the	the	DET
bionys-641	231	2	binding	binding	NOUN
bionys-641	231	3	of	of	ADP
bionys-641	231	4	parp1	parp1	NOUN
bionys-641	231	5	to	to	ADP
bionys-641	231	6	aifm1	aifm1	PROPN
bionys-641	231	7	induces	induce	VERB
bionys-641	231	8	the	the	DET
bionys-641	231	9	translocation	translocation	NOUN
bionys-641	231	10	of	of	ADP
bionys-641	231	11	aifm1	aifm1	NOUN
bionys-641	231	12	through	through	ADP
bionys-641	231	13	the	the	DET
bionys-641	231	14	mitochondria	mitochondria	NOUN
bionys-641	231	15	to	to	ADP
bionys-641	231	16	the	the	DET
bionys-641	231	17	cell	cell	NOUN
bionys-641	231	18	nucleus	nucleus	NOUN
bionys-641	231	19	,	,	PUNCT
bionys-641	231	20	leading	lead	VERB
bionys-641	231	21	to	to	ADP
bionys-641	231	22	parthanatotic	parthanatotic	ADJ
bionys-641	231	23	chromatinolysis	chromatinolysis	NOUN
bionys-641	231	24	.	.	PUNCT
bionys-641	232	1	the	the	DET
bionys-641	232	2	pathway	pathway	NOUN
bionys-641	232	3	can	can	AUX
bionys-641	232	4	be	be	AUX
bionys-641	232	5	obstructed	obstruct	VERB
bionys-641	232	6	by	by	ADP
bionys-641	232	7	reducing	reduce	VERB
bionys-641	232	8	parp1	parp1	NOUN
bionys-641	232	9	expression	expression	NOUN
bionys-641	232	10	through	through	ADP
bionys-641	232	11	the	the	DET
bionys-641	232	12	action	action	NOUN
bionys-641	232	13	of	of	ADP
bionys-641	232	14	the	the	DET
bionys-641	232	15	poly(adp	poly(adp	NOUN
bionys-641	232	16	-	-	PUNCT
bionys-641	232	17	ribose)-degrading	ribose)-degrade	VERB
bionys-641	232	18	protein	protein	NOUN
bionys-641	232	19	adpribosylhydrolase	adpribosylhydrolase	NOUN
bionys-641	232	20	-	-	PUNCT
bionys-641	232	21	like	like	ADJ
bionys-641	232	22	2	2	NUM
bionys-641	232	23	(	(	PUNCT
bionys-641	232	24	adprhl2	adprhl2	PROPN
bionys-641	232	25	,	,	PUNCT
bionys-641	232	26	often	often	ADV
bionys-641	232	27	referred	refer	VERB
bionys-641	232	28	to	to	ADP
bionys-641	232	29	as	as	ADP
bionys-641	232	30	arh3	arh3	PROPN
bionys-641	232	31	)	)	PUNCT
bionys-641	233	1	(	(	PUNCT
bionys-641	233	2	wang	wang	PROPN
bionys-641	233	3	et	et	PROPN
bionys-641	233	4	al	al	PROPN
bionys-641	233	5	.	.	PROPN
bionys-641	233	6	,	,	PUNCT
bionys-641	233	7	2011	2011	NUM
bionys-641	233	8	;	;	PUNCT
bionys-641	233	9	fernández	fernández	PROPN
bionys-641	233	10	-	-	PUNCT
bionys-641	233	11	lázaro	lázaro	NOUN
bionys-641	233	12	et	et	NOUN
bionys-641	233	13	al	al	PROPN
bionys-641	233	14	.	.	PROPN
bionys-641	233	15	,	,	PUNCT
bionys-641	233	16	2024	2024	NUM
bionys-641	233	17	)	)	PUNCT
bionys-641	233	18	.	.	PUNCT
bionys-641	234	1	recently	recently	ADV
bionys-641	234	2	,	,	PUNCT
bionys-641	234	3	it	it	PRON
bionys-641	234	4	was	be	AUX
bionys-641	234	5	discovered	discover	VERB
bionys-641	234	6	that	that	SCONJ
bionys-641	234	7	macrophage	macrophage	ADJ
bionys-641	234	8	migration	migration	NOUN
bionys-641	234	9	inhibitory	inhibitory	ADJ
bionys-641	234	10	factor	factor	NOUN
bionys-641	234	11	(	(	PUNCT
bionys-641	234	12	mif	mif	PROPN
bionys-641	234	13	)	)	PUNCT
bionys-641	234	14	is	be	AUX
bionys-641	234	15	an	an	DET
bionys-641	234	16	aifm1	aifm1	NOUN
bionys-641	234	17	-	-	PUNCT
bionys-641	234	18	binding	bind	VERB
bionys-641	234	19	protein	protein	NOUN
bionys-641	234	20	with	with	ADP
bionys-641	234	21	nuclease	nuclease	NOUN
bionys-641	234	22	activity	activity	NOUN
bionys-641	234	23	that	that	PRON
bionys-641	234	24	produces	produce	VERB
bionys-641	234	25	large	large	ADJ
bionys-641	234	26	dna	dna	NOUN
bionys-641	234	27	fragments	fragment	NOUN
bionys-641	234	28	during	during	ADP
bionys-641	234	29	parthanatos	parthanatos	ADJ
bionys-641	234	30	induction	induction	NOUN
bionys-641	234	31	(	(	PUNCT
bionys-641	234	32	weiß	weiß	NOUN
bionys-641	234	33	et	et	NOUN
bionys-641	234	34	al	al	PROPN
bionys-641	234	35	.	.	PROPN
bionys-641	234	36	,	,	PUNCT
bionys-641	234	37	2023	2023	NUM
bionys-641	234	38	)	)	PUNCT
bionys-641	234	39	.	.	PUNCT
bionys-641	235	1	entosis	entosis	NOUN
bionys-641	235	2	is	be	AUX
bionys-641	235	3	a	a	DET
bionys-641	235	4	form	form	NOUN
bionys-641	235	5	of	of	ADP
bionys-641	235	6	cellular	cellular	ADJ
bionys-641	235	7	cannibalism	cannibalism	NOUN
bionys-641	235	8	wherein	wherein	SCONJ
bionys-641	235	9	one	one	NUM
bionys-641	235	10	cell	cell	NOUN
bionys-641	235	11	swallows	swallow	NOUN
bionys-641	235	12	and	and	CCONJ
bionys-641	235	13	annihilates	annihilate	VERB
bionys-641	235	14	another	another	PRON
bionys-641	235	15	.	.	PUNCT
bionys-641	236	1	entosis	entosis	NOUN
bionys-641	236	2	and	and	CCONJ
bionys-641	236	3	entotic	entotic	ADJ
bionys-641	236	4	cell	cell	NOUN
bionys-641	236	5	death	death	NOUN
bionys-641	236	6	mostly	mostly	ADV
bionys-641	236	7	transpire	transpire	VERB
bionys-641	236	8	in	in	ADP
bionys-641	236	9	epithelial	epithelial	ADJ
bionys-641	236	10	tumor	tumor	NOUN
bionys-641	236	11	cells	cell	NOUN
bionys-641	236	12	under	under	ADP
bionys-641	236	13	several	several	ADJ
bionys-641	236	14	situations	situation	NOUN
bionys-641	236	15	,	,	PUNCT
bionys-641	236	16	including	include	VERB
bionys-641	236	17	abnormal	abnormal	ADJ
bionys-641	236	18	proliferation	proliferation	NOUN
bionys-641	236	19	,	,	PUNCT
bionys-641	236	20	glucose	glucose	NOUN
bionys-641	236	21	deficiency	deficiency	NOUN
bionys-641	236	22	,	,	PUNCT
bionys-641	236	23	matrixinduced	matrixinduced	ADJ
bionys-641	236	24	mortality	mortality	NOUN
bionys-641	236	25	,	,	PUNCT
bionys-641	236	26	and	and	CCONJ
bionys-641	236	27	mitotic	mitotic	ADJ
bionys-641	236	28	pressure	pressure	NOUN
bionys-641	236	29	(	(	PUNCT
bionys-641	236	30	durgan	durgan	VERB
bionys-641	236	31	et	et	PROPN
bionys-641	236	32	al	al	PROPN
bionys-641	236	33	.	.	PROPN
bionys-641	236	34	,	,	PUNCT
bionys-641	236	35	2017	2017	NUM
bionys-641	236	36	)	)	PUNCT
bionys-641	236	37	.	.	PUNCT
bionys-641	237	1	entosis	entosis	NOUN
bionys-641	237	2	is	be	AUX
bionys-641	237	3	demonstrated	demonstrate	VERB
bionys-641	237	4	by	by	ADP
bionys-641	237	5	the	the	DET
bionys-641	237	6	appearance	appearance	NOUN
bionys-641	237	7	of	of	ADP
bionys-641	237	8	cell	cell	NOUN
bionys-641	237	9	-	-	PUNCT
bionys-641	237	10	in	in	ADP
bionys-641	237	11	-	-	PUNCT
bionys-641	237	12	cell	cell	NOUN
bionys-641	237	13	structures	structure	NOUN
bionys-641	237	14	in	in	ADP
bionys-641	237	15	cancer	cancer	NOUN
bionys-641	237	16	patients	patient	NOUN
bionys-641	237	17	'	'	PART
bionys-641	237	18	urine	urine	NOUN
bionys-641	237	19	and	and	CCONJ
bionys-641	237	20	ascitic	ascitic	ADJ
bionys-641	237	21	fluid	fluid	NOUN
bionys-641	237	22	,	,	PUNCT
bionys-641	237	23	with	with	ADP
bionys-641	237	24	a	a	DET
bionys-641	237	25	frequency	frequency	NOUN
bionys-641	237	26	proportionate	proportionate	NOUN
bionys-641	237	27	to	to	ADP
bionys-641	237	28	tumor	tumor	NOUN
bionys-641	237	29	stage	stage	NOUN
bionys-641	237	30	.	.	PUNCT
bionys-641	238	1	cell	cell	NOUN
bionys-641	238	2	adhesion	adhesion	NOUN
bionys-641	238	3	and	and	CCONJ
bionys-641	238	4	cytoskeletal	cytoskeletal	ADJ
bionys-641	238	5	rearrangement	rearrangement	ADJ
bionys-641	238	6	pathways	pathway	NOUN
bionys-641	238	7	are	be	AUX
bionys-641	238	8	crucial	crucial	ADJ
bionys-641	238	9	in	in	ADP
bionys-641	238	10	controlling	control	VERB
bionys-641	238	11	entosis	entosis	NOUN
bionys-641	238	12	induction	induction	NOUN
bionys-641	238	13	,	,	PUNCT
bionys-641	238	14	even	even	ADV
bionys-641	238	15	if	if	SCONJ
bionys-641	238	16	the	the	DET
bionys-641	238	17	underlying	underlying	ADJ
bionys-641	238	18	mechanisms	mechanism	NOUN
bionys-641	238	19	are	be	AUX
bionys-641	238	20	unclear	unclear	ADJ
bionys-641	238	21	.	.	PUNCT
bionys-641	239	1	entotic	entotic	ADJ
bionys-641	239	2	cell	cell	NOUN
bionys-641	239	3	death	death	NOUN
bionys-641	239	4	entails	entail	VERB
bionys-641	239	5	the	the	DET
bionys-641	239	6	digestion	digestion	NOUN
bionys-641	239	7	of	of	ADP
bionys-641	239	8	ingested	ingest	VERB
bionys-641	239	9	cells	cell	NOUN
bionys-641	239	10	by	by	ADP
bionys-641	239	11	host	host	NOUN
bionys-641	239	12	cells	cell	NOUN
bionys-641	239	13	,	,	PUNCT
bionys-641	239	14	involving	involve	VERB
bionys-641	239	15	lc3	lc3	NOUN
bionys-641	239	16	-	-	PUNCT
bionys-641	239	17	associated	associate	VERB
bionys-641	239	18	phagocytosis	phagocytosis	NOUN
bionys-641	239	19	(	(	PUNCT
bionys-641	239	20	lap	lap	NOUN
bionys-641	239	21	)	)	PUNCT
bionys-641	239	22	and	and	CCONJ
bionys-641	239	23	the	the	DET
bionys-641	239	24	cathepsin	cathepsin	PROPN
bionys-641	239	25	b	b	NOUN
bionys-641	239	26	-	-	PUNCT
bionys-641	239	27	mediated	mediate	VERB
bionys-641	239	28	lysosomal	lysosomal	ADJ
bionys-641	239	29	degradation	degradation	NOUN
bionys-641	239	30	cascade	cascade	NOUN
bionys-641	239	31	(	(	PUNCT
bionys-641	239	32	martins	martin	NOUN
bionys-641	239	33	et	et	NOUN
bionys-641	239	34	al	al	PROPN
bionys-641	239	35	.	.	PROPN
bionys-641	239	36	,	,	PUNCT
bionys-641	239	37	2017	2017	NUM
bionys-641	239	38	)	)	PUNCT
bionys-641	239	39	.	.	PUNCT
bionys-641	240	1	entosis	entosis	NOUN
bionys-641	240	2	,	,	PUNCT
bionys-641	240	3	however	however	ADV
bionys-641	240	4	,	,	PUNCT
bionys-641	240	5	does	do	AUX
bionys-641	240	6	not	not	PART
bionys-641	240	7	include	include	VERB
bionys-641	240	8	effector	effector	NOUN
bionys-641	240	9	caspases	caspase	NOUN
bionys-641	240	10	and	and	CCONJ
bionys-641	240	11	unregulated	unregulate	VERB
bionys-641	240	12	by	by	ADP
bionys-641	240	13	bcl2	bcl2	NOUN
bionys-641	240	14	family	family	NOUN
bionys-641	240	15	proteins	protein	NOUN
bionys-641	240	16	,	,	PUNCT
bionys-641	240	17	important	important	ADJ
bionys-641	240	18	apoptotic	apoptotic	ADJ
bionys-641	240	19	characteristics	characteristic	NOUN
bionys-641	240	20	(	(	PUNCT
bionys-641	240	21	li	li	PROPN
bionys-641	240	22	et	et	PROPN
bionys-641	240	23	al	al	PROPN
bionys-641	240	24	.	.	PROPN
bionys-641	240	25	,	,	PUNCT
bionys-641	240	26	2015	2015	NUM
bionys-641	240	27	)	)	PUNCT
bionys-641	240	28	.	.	PUNCT
bionys-641	241	1	netotic	netotic	ADJ
bionys-641	241	2	cell	cell	NOUN
bionys-641	241	3	death	death	NOUN
bionys-641	241	4	(	(	PUNCT
bionys-641	241	5	netosis	netosis	NOUN
bionys-641	241	6	)	)	PUNCT
bionys-641	241	7	is	be	AUX
bionys-641	241	8	a	a	DET
bionys-641	241	9	form	form	NOUN
bionys-641	241	10	of	of	ADP
bionys-641	241	11	rcd	rcd	PROPN
bionys-641	241	12	characterized	characterize	VERB
bionys-641	241	13	by	by	ADP
bionys-641	241	14	the	the	DET
bionys-641	241	15	expulsion	expulsion	NOUN
bionys-641	241	16	of	of	ADP
bionys-641	241	17	neutrophil	neutrophil	ADJ
bionys-641	241	18	extracellular	extracellular	ADJ
bionys-641	241	19	traps	trap	NOUN
bionys-641	241	20	(	(	PUNCT
bionys-641	241	21	nets	net	NOUN
bionys-641	241	22	)	)	PUNCT
bionys-641	241	23	(	(	PUNCT
bionys-641	241	24	liana	liana	NOUN
bionys-641	241	25	et	et	PROPN
bionys-641	241	26	al	al	PROPN
bionys-641	241	27	.	.	PROPN
bionys-641	241	28	,	,	PUNCT
bionys-641	241	29	2022a	2022a	NUM
bionys-641	241	30	)	)	PUNCT
bionys-641	241	31	.	.	PUNCT
bionys-641	242	1	nets	net	NOUN
bionys-641	242	2	are	be	AUX
bionys-641	242	3	protein	protein	NOUN
bionys-641	242	4	structures	structure	NOUN
bionys-641	242	5	resembling	resemble	VERB
bionys-641	242	6	dna	dna	NOUN
bionys-641	242	7	generated	generate	VERB
bionys-641	242	8	by	by	ADP
bionys-641	242	9	cells	cell	NOUN
bionys-641	242	10	reacting	react	VERB
bionys-641	242	11	to	to	ADP
bionys-641	242	12	viral	viral	ADJ
bionys-641	242	13	or	or	CCONJ
bionys-641	242	14	non	non	ADJ
bionys-641	242	15	-	-	ADJ
bionys-641	242	16	infectious	infectious	ADJ
bionys-641	242	17	stimuli	stimulus	NOUN
bionys-641	242	18	.	.	PUNCT
bionys-641	243	1	elevated	elevate	VERB
bionys-641	243	2	netosis	netosis	ADV
bionys-641	243	3	not	not	PART
bionys-641	243	4	only	only	ADV
bionys-641	243	5	inhibits	inhibit	VERB
bionys-641	243	6	the	the	DET
bionys-641	243	7	advancement	advancement	NOUN
bionys-641	243	8	of	of	ADP
bionys-641	243	9	pathogenic	pathogenic	ADJ
bionys-641	243	10	infiltration	infiltration	NOUN
bionys-641	243	11	by	by	ADP
bionys-641	243	12	sequestering	sequester	VERB
bionys-641	243	13	harmful	harmful	ADJ
bionys-641	243	14	organisms	organism	NOUN
bionys-641	243	15	but	but	CCONJ
bionys-641	243	16	also	also	ADV
bionys-641	243	17	induces	induce	VERB
bionys-641	243	18	the	the	DET
bionys-641	243	19	release	release	NOUN
bionys-641	243	20	of	of	ADP
bionys-641	243	21	damps	damp	NOUN
bionys-641	243	22	.	.	PUNCT
bionys-641	244	1	this	this	DET
bionys-641	244	2	process	process	NOUN
bionys-641	244	3	may	may	AUX
bionys-641	244	4	result	result	VERB
bionys-641	244	5	in	in	ADP
bionys-641	244	6	autoimmune	autoimmune	ADJ
bionys-641	244	7	disorders	disorder	NOUN
bionys-641	244	8	(	(	PUNCT
bionys-641	244	9	liana	liana	NOUN
bionys-641	244	10	et	et	PROPN
bionys-641	244	11	al	al	PROPN
bionys-641	244	12	.	.	PROPN
bionys-641	244	13	,	,	PUNCT
bionys-641	244	14	2022b	2022b	NUM
bionys-641	244	15	)	)	PUNCT
bionys-641	244	16	.	.	PUNCT
bionys-641	245	1	netosis	netosis	NOUN
bionys-641	245	2	is	be	AUX
bionys-641	245	3	a	a	DET
bionys-641	245	4	dynamic	dynamic	ADJ
bionys-641	245	5	process	process	NOUN
bionys-641	245	6	that	that	PRON
bionys-641	245	7	responds	respond	VERB
bionys-641	245	8	to	to	ADP
bionys-641	245	9	several	several	ADJ
bionys-641	245	10	stimuli	stimulus	NOUN
bionys-641	245	11	,	,	PUNCT
bionys-641	245	12	including	include	VERB
bionys-641	245	13	ros	ros	PROPN
bionys-641	245	14	production	production	NOUN
bionys-641	245	15	by	by	ADP
bionys-641	245	16	nadph	nadph	ADJ
bionys-641	245	17	oxidase	oxidase	NOUN
bionys-641	245	18	,	,	PUNCT
bionys-641	245	19	autophagy	autophagy	NOUN
bionys-641	245	20	,	,	PUNCT
bionys-641	245	21	and	and	CCONJ
bionys-641	245	22	the	the	DET
bionys-641	245	23	secretion	secretion	NOUN
bionys-641	245	24	and	and	CCONJ
bionys-641	245	25	transference	transference	NOUN
bionys-641	245	26	of	of	ADP
bionys-641	245	27	granule	granule	NOUN
bionys-641	245	28	enzymes	enzyme	NOUN
bionys-641	245	29	such	such	ADJ
bionys-641	245	30	as	as	ADP
bionys-641	245	31	elastase	elastase	NOUN
bionys-641	245	32	,	,	PUNCT
bionys-641	245	33	matrix	matrix	NOUN
bionys-641	245	34	metalloproteinase	metalloproteinase	NOUN
bionys-641	245	35	(	(	PUNCT
bionys-641	245	36	mmp	mmp	PROPN
bionys-641	245	37	)	)	PUNCT
bionys-641	245	38	,	,	PUNCT
bionys-641	245	39	and	and	CCONJ
bionys-641	245	40	myeloperoxidase	myeloperoxidase	NOUN
bionys-641	245	41	.	.	PUNCT
bionys-641	246	1	subsequently	subsequently	ADV
bionys-641	246	2	,	,	PUNCT
bionys-641	246	3	histone	histone	NOUN
bionys-641	246	4	citrullination	citrullination	NOUN
bionys-641	246	5	occurs	occur	VERB
bionys-641	246	6	,	,	PUNCT
bionys-641	246	7	characterized	characterize	VERB
bionys-641	246	8	by	by	ADP
bionys-641	246	9	chromatin	chromatin	NOUN
bionys-641	246	10	decondensation	decondensation	PROPN
bionys-641	246	11	,	,	PUNCT
bionys-641	246	12	cellular	cellular	ADJ
bionys-641	246	13	membrane	membrane	NOUN
bionys-641	246	14	disintegration	disintegration	NOUN
bionys-641	246	15	,	,	PUNCT
bionys-641	246	16	and	and	CCONJ
bionys-641	246	17	the	the	DET
bionys-641	246	18	release	release	NOUN
bionys-641	246	19	of	of	ADP
bionys-641	246	20	chromatin	chromatin	NOUN
bionys-641	246	21	fibers	fiber	NOUN
bionys-641	246	22	(	(	PUNCT
bionys-641	246	23	jorch	jorch	NOUN
bionys-641	246	24	&	&	CCONJ
bionys-641	246	25	kubes	kube	NOUN
bionys-641	246	26	,	,	PUNCT
bionys-641	246	27	2017	2017	NUM
bionys-641	246	28	)	)	PUNCT
bionys-641	246	29	.	.	PUNCT
bionys-641	247	1	lcd	lcd	NOUN
bionys-641	247	2	,	,	PUNCT
bionys-641	247	3	frequently	frequently	ADV
bionys-641	247	4	referred	refer	VERB
bionys-641	247	5	to	to	ADP
bionys-641	247	6	as	as	ADP
bionys-641	247	7	lysosomal	lysosomal	ADJ
bionys-641	247	8	cell	cell	NOUN
bionys-641	247	9	death	death	NOUN
bionys-641	247	10	,	,	PUNCT
bionys-641	247	11	is	be	AUX
bionys-641	247	12	an	an	DET
bionys-641	247	13	instance	instance	NOUN
bionys-641	247	14	of	of	ADP
bionys-641	247	15	rcd	rcd	PROPN
bionys-641	247	16	caused	cause	VERB
bionys-641	247	17	by	by	ADP
bionys-641	247	18	the	the	DET
bionys-641	247	19	ejection	ejection	NOUN
bionys-641	247	20	of	of	ADP
bionys-641	247	21	hydrolytic	hydrolytic	ADJ
bionys-641	247	22	enzymes	enzyme	NOUN
bionys-641	247	23	into	into	ADP
bionys-641	247	24	the	the	DET
bionys-641	247	25	cytoplasm	cytoplasm	NOUN
bionys-641	247	26	as	as	ADP
bionys-641	247	27	a	a	DET
bionys-641	247	28	consequence	consequence	NOUN
bionys-641	247	29	of	of	ADP
bionys-641	247	30	lysosomal	lysosomal	ADJ
bionys-641	247	31	barrier	barrier	NOUN
bionys-641	247	32	perforation	perforation	NOUN
bionys-641	247	33	.	.	PUNCT
bionys-641	248	1	this	this	DET
bionys-641	248	2	process	process	NOUN
bionys-641	248	3	happens	happen	VERB
bionys-641	248	4	when	when	SCONJ
bionys-641	248	5	cells	cell	NOUN
bionys-641	248	6	are	be	AUX
bionys-641	248	7	exposed	expose	VERB
bionys-641	248	8	to	to	ADP
bionys-641	248	9	lysosomotropic	lysosomotropic	ADJ
bionys-641	248	10	detergents	detergent	NOUN
bionys-641	248	11	(	(	PUNCT
bionys-641	248	12	sphingosine	sphingosine	NOUN
bionys-641	248	13	or	or	CCONJ
bionys-641	248	14	phosphatidic	phosphatidic	ADJ
bionys-641	248	15	acid	acid	NOUN
bionys-641	248	16	)	)	PUNCT
bionys-641	248	17	and	and	CCONJ
bionys-641	248	18	ros	ros	PROPN
bionys-641	248	19	(	(	PUNCT
bionys-641	248	20	fogde	fogde	PROPN
bionys-641	248	21	et	et	PROPN
bionys-641	248	22	al	al	PROPN
bionys-641	248	23	.	.	PROPN
bionys-641	248	24	,	,	PUNCT
bionys-641	248	25	2022	2022	NUM
bionys-641	248	26	)	)	PUNCT
bionys-641	248	27	.	.	PUNCT
bionys-641	249	1	cathepsins	cathepsin	NOUN
bionys-641	249	2	,	,	PUNCT
bionys-641	249	3	a	a	DET
bionys-641	249	4	class	class	NOUN
bionys-641	249	5	of	of	ADP
bionys-641	249	6	lysosomal	lysosomal	ADJ
bionys-641	249	7	hydrolase	hydrolase	NOUN
bionys-641	249	8	enzymes	enzyme	NOUN
bionys-641	249	9	,	,	PUNCT
bionys-641	249	10	are	be	AUX
bionys-641	249	11	essential	essential	ADJ
bionys-641	249	12	in	in	ADP
bionys-641	249	13	lysosomal	lysosomal	ADJ
bionys-641	249	14	degradation	degradation	NOUN
bionys-641	249	15	.	.	PUNCT
bionys-641	250	1	inhibition	inhibition	NOUN
bionys-641	250	2	of	of	ADP
bionys-641	250	3	cathepsin	cathepsin	NOUN
bionys-641	250	4	expression	expression	NOUN
bionys-641	250	5	or	or	CCONJ
bionys-641	250	6	action	action	NOUN
bionys-641	250	7	can	can	AUX
bionys-641	250	8	avert	avert	VERB
bionys-641	250	9	lcd	lcd	PROPN
bionys-641	250	10	.	.	PUNCT
bionys-641	251	1	nonetheless	nonetheless	ADV
bionys-641	251	2	,	,	PUNCT
bionys-641	251	3	cathepsin	cathepsin	NOUN
bionys-641	251	4	is	be	AUX
bionys-641	251	5	not	not	PART
bionys-641	251	6	the	the	DET
bionys-641	251	7	sole	sole	ADJ
bionys-641	251	8	contributor	contributor	NOUN
bionys-641	251	9	to	to	ADP
bionys-641	251	10	lcd	lcd	VERB
bionys-641	251	11	,	,	PUNCT
bionys-641	251	12	as	as	SCONJ
bionys-641	251	13	lysosomes	lysosome	NOUN
bionys-641	251	14	also	also	ADV
bionys-641	251	15	sequester	sequester	VERB
bionys-641	251	16	excess	excess	ADJ
bionys-641	251	17	iron	iron	NOUN
bionys-641	251	18	(	(	PUNCT
bionys-641	251	19	lin	lin	PROPN
bionys-641	251	20	et	et	PROPN
bionys-641	251	21	al	al	PROPN
bionys-641	251	22	.	.	PROPN
bionys-641	251	23	,	,	PUNCT
bionys-641	251	24	2010	2010	NUM
bionys-641	251	25	)	)	PUNCT
bionys-641	251	26	.	.	PUNCT
bionys-641	252	1	this	this	PRON
bionys-641	252	2	implies	imply	VERB
bionys-641	252	3	that	that	SCONJ
bionys-641	252	4	lysosomal	lysosomal	ADJ
bionys-641	252	5	membrane	membrane	NOUN
bionys-641	252	6	permeation	permeation	NOUN
bionys-641	252	7	could	could	AUX
bionys-641	252	8	contribute	contribute	VERB
bionys-641	252	9	to	to	ADP
bionys-641	252	10	the	the	DET
bionys-641	252	11	expulsion	expulsion	NOUN
bionys-641	252	12	of	of	ADP
bionys-641	252	13	this	this	DET
bionys-641	252	14	hazardous	hazardous	ADJ
bionys-641	252	15	metal	metal	NOUN
bionys-641	252	16	into	into	ADP
bionys-641	252	17	the	the	DET
bionys-641	252	18	cytosol	cytosol	NOUN
bionys-641	252	19	,	,	PUNCT
bionys-641	252	20	thus	thus	ADV
bionys-641	252	21	triggering	trigger	VERB
bionys-641	252	22	ferroptosis	ferroptosis	NOUN
bionys-641	252	23	,	,	PUNCT
bionys-641	252	24	which	which	PRON
bionys-641	252	25	was	be	AUX
bionys-641	252	26	discussed	discuss	VERB
bionys-641	252	27	in	in	ADP
bionys-641	252	28	a	a	DET
bionys-641	252	29	previous	previous	ADJ
bionys-641	252	30	section	section	NOUN
bionys-641	252	31	(	(	PUNCT
bionys-641	252	32	min	min	PROPN
bionys-641	252	33	&	&	CCONJ
bionys-641	252	34	kwon	kwon	PROPN
bionys-641	252	35	,	,	PUNCT
bionys-641	252	36	2020	2020	NUM
bionys-641	252	37	)	)	PUNCT
bionys-641	252	38	.	.	PUNCT
bionys-641	253	1	alkaliptosis	alkaliptosis	ADJ
bionys-641	253	2	is	be	AUX
bionys-641	253	3	a	a	DET
bionys-641	253	4	newly	newly	ADV
bionys-641	253	5	identified	identify	VERB
bionys-641	253	6	type	type	NOUN
bionys-641	253	7	of	of	ADP
bionys-641	253	8	rcd	rcd	PROPN
bionys-641	253	9	that	that	PRON
bionys-641	253	10	initiates	initiate	VERB
bionys-641	253	11	through	through	ADP
bionys-641	253	12	intracellular	intracellular	ADJ
bionys-641	253	13	alkalinization	alkalinization	NOUN
bionys-641	253	14	(	(	PUNCT
bionys-641	253	15	song	song	NOUN
bionys-641	253	16	et	et	PROPN
bionys-641	253	17	al	al	PROPN
bionys-641	253	18	.	.	PROPN
bionys-641	253	19	,	,	PUNCT
bionys-641	253	20	2018	2018	NUM
bionys-641	253	21	)	)	PUNCT
bionys-641	253	22	.	.	PUNCT
bionys-641	254	1	disruption	disruption	NOUN
bionys-641	254	2	of	of	ADP
bionys-641	254	3	the	the	DET
bionys-641	254	4	nuclear	nuclear	ADJ
bionys-641	254	5	factor	factor	NOUN
bionys-641	254	6	kappa	kappa	PROPN
bionys-641	254	7	b	b	PROPN
bionys-641	254	8	kinase	kinase	PROPN
bionys-641	254	9	subunit	subunit	NOUN
bionys-641	254	10	beta	beta	NOUN
bionys-641	254	11	(	(	PUNCT
bionys-641	254	12	ikbkb	ikbkb	NOUN
bionys-641	254	13	,	,	PUNCT
bionys-641	254	14	or	or	CCONJ
bionys-641	254	15	ikkβ)nf;κβ	ikkβ)nf;κβ	ADJ
bionys-641	254	16	pathway	pathway	NOUN
bionys-641	254	17	,	,	PUNCT
bionys-641	254	18	which	which	PRON
bionys-641	254	19	leads	lead	VERB
bionys-641	254	20	to	to	ADP
bionys-641	254	21	the	the	DET
bionys-641	254	22	downregulation	downregulation	NOUN
bionys-641	254	23	of	of	ADP
bionys-641	254	24	carbonic	carbonic	ADJ
bionys-641	254	25	anhydrase	anhydrase	NOUN
bionys-641	254	26	9	9	NUM
bionys-641	254	27	(	(	PUNCT
bionys-641	254	28	ca9	ca9	NOUN
bionys-641	254	29	)	)	PUNCT
bionys-641	254	30	,	,	PUNCT
bionys-641	254	31	an	an	DET
bionys-641	254	32	enzyme	enzyme	NOUN
bionys-641	254	33	critical	critical	ADJ
bionys-641	254	34	for	for	ADP
bionys-641	254	35	ph	ph	ADJ
bionys-641	254	36	regulation	regulation	NOUN
bionys-641	254	37	,	,	PUNCT
bionys-641	254	38	is	be	AUX
bionys-641	254	39	an	an	DET
bionys-641	254	40	essential	essential	ADJ
bionys-641	254	41	alkaliptosis	alkaliptosis	ADJ
bionys-641	254	42	mediator	mediator	NOUN
bionys-641	254	43	(	(	PUNCT
bionys-641	254	44	liu	liu	PROPN
bionys-641	254	45	et	et	PROPN
bionys-641	254	46	al	al	PROPN
bionys-641	254	47	.	.	PROPN
bionys-641	254	48	,	,	PUNCT
bionys-641	254	49	2019	2019	NUM
bionys-641	254	50	)	)	PUNCT
bionys-641	254	51	.	.	PUNCT
bionys-641	255	1	it	it	PRON
bionys-641	255	2	was	be	AUX
bionys-641	255	3	determined	determine	VERB
bionys-641	255	4	following	follow	VERB
bionys-641	255	5	jtc801	jtc801	PROPN
bionys-641	255	6	administration	administration	PROPN
bionys-641	255	7	,	,	PUNCT
bionys-641	255	8	an	an	DET
bionys-641	255	9	opioid	opioid	ADJ
bionys-641	255	10	analgesic	analgesic	NOUN
bionys-641	255	11	,	,	PUNCT
bionys-641	255	12	which	which	PRON
bionys-641	255	13	effectively	effectively	ADV
bionys-641	255	14	eradicates	eradicate	VERB
bionys-641	255	15	cell	cell	NOUN
bionys-641	255	16	lines	line	NOUN
bionys-641	255	17	of	of	ADP
bionys-641	255	18	human	human	ADJ
bionys-641	255	19	malignancies	malignancy	NOUN
bionys-641	255	20	,	,	PUNCT
bionys-641	255	21	causing	cause	VERB
bionys-641	255	22	cellular	cellular	ADJ
bionys-641	255	23	demise	demise	NOUN
bionys-641	255	24	that	that	PRON
bionys-641	255	25	are	be	AUX
bionys-641	255	26	not	not	PART
bionys-641	255	27	characteristic	characteristic	ADJ
bionys-641	255	28	of	of	ADP
bionys-641	255	29	with	with	ADP
bionys-641	255	30	apoptosis	apoptosis	NOUN
bionys-641	255	31	,	,	PUNCT
bionys-641	255	32	necroptosis	necroptosis	NOUN
bionys-641	255	33	,	,	PUNCT
bionys-641	255	34	autophagy	autophagy	NOUN
bionys-641	255	35	,	,	PUNCT
bionys-641	255	36	or	or	CCONJ
bionys-641	255	37	ferroptosis	ferroptosis	NOUN
bionys-641	255	38	(	(	PUNCT
bionys-641	255	39	song	song	NOUN
bionys-641	255	40	et	et	PROPN
bionys-641	255	41	al	al	PROPN
bionys-641	255	42	.	.	PROPN
bionys-641	255	43	,	,	PUNCT
bionys-641	255	44	2018	2018	NUM
bionys-641	255	45	)	)	PUNCT
bionys-641	255	46	.	.	PUNCT
bionys-641	256	1	anoikis	anoiki	NOUN
bionys-641	256	2	is	be	AUX
bionys-641	256	3	a	a	DET
bionys-641	256	4	specific	specific	ADJ
bionys-641	256	5	type	type	NOUN
bionys-641	256	6	of	of	ADP
bionys-641	256	7	rcd	rcd	PROPN
bionys-641	256	8	that	that	PRON
bionys-641	256	9	prohibits	prohibit	VERB
bionys-641	256	10	detached	detached	ADJ
bionys-641	256	11	cells	cell	NOUN
bionys-641	256	12	from	from	ADP
bionys-641	256	13	surviving	survive	VERB
bionys-641	256	14	and	and	CCONJ
bionys-641	256	15	populating	populate	VERB
bionys-641	256	16	in	in	ADP
bionys-641	256	17	the	the	DET
bionys-641	256	18	wrong	wrong	ADJ
bionys-641	256	19	places	place	NOUN
bionys-641	256	20	.	.	PUNCT
bionys-641	257	1	this	this	PRON
bionys-641	257	2	is	be	AUX
bionys-641	257	3	a	a	DET
bionys-641	257	4	vital	vital	ADJ
bionys-641	257	5	process	process	NOUN
bionys-641	257	6	for	for	ADP
bionys-641	257	7	preserving	preserve	VERB
bionys-641	257	8	tissue	tissue	NOUN
bionys-641	257	9	homeostasis	homeostasis	NOUN
bionys-641	257	10	,	,	PUNCT
bionys-641	257	11	making	make	VERB
bionys-641	257	12	cells	cell	NOUN
bionys-641	257	13	die	die	VERB
bionys-641	257	14	after	after	ADP
bionys-641	257	15	their	their	PRON
bionys-641	257	16	detachment	detachment	NOUN
bionys-641	257	17	from	from	ADP
bionys-641	257	18	the	the	DET
bionys-641	257	19	extracellular	extracellular	ADJ
bionys-641	257	20	matrix	matrix	NOUN
bionys-641	257	21	(	(	PUNCT
bionys-641	257	22	ecm	ecm	PROPN
bionys-641	257	23	)	)	PUNCT
bionys-641	257	24	(	(	PUNCT
bionys-641	257	25	taddei	taddei	NOUN
bionys-641	257	26	et	et	PROPN
bionys-641	257	27	al	al	PROPN
bionys-641	257	28	.	.	PROPN
bionys-641	257	29	,	,	PUNCT
bionys-641	257	30	2012	2012	NUM
bionys-641	257	31	)	)	PUNCT
bionys-641	257	32	.	.	PUNCT
bionys-641	258	1	this	this	DET
bionys-641	258	2	phenomenon	phenomenon	NOUN
bionys-641	258	3	is	be	AUX
bionys-641	258	4	especially	especially	ADV
bionys-641	258	5	significant	significant	ADJ
bionys-641	258	6	for	for	ADP
bionys-641	258	7	epithelial	epithelial	ADJ
bionys-641	258	8	and	and	CCONJ
bionys-641	258	9	endothelial	endothelial	ADJ
bionys-641	258	10	cells	cell	NOUN
bionys-641	258	11	,	,	PUNCT
bionys-641	258	12	which	which	PRON
bionys-641	258	13	greatly	greatly	ADV
bionys-641	258	14	depend	depend	VERB
bionys-641	258	15	on	on	ADP
bionys-641	258	16	interactions	interaction	NOUN
bionys-641	258	17	with	with	ADP
bionys-641	258	18	the	the	DET
bionys-641	258	19	ecm	ecm	NOUN
bionys-641	258	20	for	for	ADP
bionys-641	258	21	survival	survival	NOUN
bionys-641	258	22	and	and	CCONJ
bionys-641	258	23	appropriate	appropriate	ADJ
bionys-641	258	24	function	function	NOUN
bionys-641	258	25	(	(	PUNCT
bionys-641	258	26	giannoni	giannoni	PROPN
bionys-641	258	27	et	et	PROPN
bionys-641	258	28	al	al	PROPN
bionys-641	258	29	.	.	PROPN
bionys-641	258	30	,	,	PUNCT
bionys-641	258	31	2008	2008	NUM
bionys-641	258	32	)	)	PUNCT
bionys-641	258	33	.	.	PUNCT
bionys-641	259	1	moreover	moreover	ADV
bionys-641	259	2	,	,	PUNCT
bionys-641	259	3	anoikis	anoiki	NOUN
bionys-641	259	4	is	be	AUX
bionys-641	259	5	essential	essential	ADJ
bionys-641	259	6	to	to	PART
bionys-641	259	7	prevent	prevent	VERB
bionys-641	259	8	metastasis	metastasis	NOUN
bionys-641	259	9	of	of	ADP
bionys-641	259	10	cancer	cancer	NOUN
bionys-641	259	11	cells	cell	NOUN
bionys-641	259	12	.	.	PUNCT
bionys-641	260	1	however	however	ADV
bionys-641	260	2	,	,	PUNCT
bionys-641	260	3	in	in	ADP
bionys-641	260	4	some	some	DET
bionys-641	260	5	cases	case	NOUN
bionys-641	260	6	,	,	PUNCT
bionys-641	260	7	cancer	cancer	NOUN
bionys-641	260	8	cells	cell	NOUN
bionys-641	260	9	develop	develop	VERB
bionys-641	260	10	an	an	DET
bionys-641	260	11	anoikis	anoiki	NOUN
bionys-641	260	12	resistance	resistance	NOUN
bionys-641	260	13	,	,	PUNCT
bionys-641	260	14	which	which	PRON
bionys-641	260	15	allows	allow	VERB
bionys-641	260	16	them	they	PRON
bionys-641	260	17	to	to	PART
bionys-641	260	18	enter	enter	VERB
bionys-641	260	19	the	the	DET
bionys-641	260	20	metastatic	metastatic	ADJ
bionys-641	260	21	cascade	cascade	NOUN
bionys-641	260	22	,	,	PUNCT
bionys-641	260	23	such	such	ADJ
bionys-641	260	24	as	as	ADP
bionys-641	260	25	by	by	ADP
bionys-641	260	26	the	the	DET
bionys-641	260	27	involvement	involvement	NOUN
bionys-641	260	28	of	of	ADP
bionys-641	260	29	the	the	DET
bionys-641	260	30	muc1	muc1	ADJ
bionys-641	260	31	extracellular	extracellular	ADJ
bionys-641	260	32	domain	domain	NOUN
bionys-641	260	33	.	.	PUNCT
bionys-641	261	1	it	it	PRON
bionys-641	261	2	enables	enable	VERB
bionys-641	261	3	cancer	cancer	NOUN
bionys-641	261	4	cells	cell	NOUN
bionys-641	261	5	to	to	PART
bionys-641	261	6	withstand	withstand	VERB
bionys-641	261	7	detachment	detachment	NOUN
bionys-641	261	8	,	,	PUNCT
bionys-641	261	9	infiltrate	infiltrate	VERB
bionys-641	261	10	the	the	DET
bionys-641	261	11	lymphatic	lymphatic	ADJ
bionys-641	261	12	or	or	CCONJ
bionys-641	261	13	blood	blood	NOUN
bionys-641	261	14	biologica	biologica	PROPN
bionys-641	261	15	nyssana	nyssana	PROPN
bionys-641	262	1	●	●	PUNCT
bionys-641	262	2	16	16	NUM
bionys-641	262	3	(	(	PUNCT
bionys-641	262	4	2	2	NUM
bionys-641	262	5	)	)	PUNCT
bionys-641	262	6	december	december	PROPN
bionys-641	262	7	2025	2025	NUM
bionys-641	262	8	:	:	PUNCT
bionys-641	262	9	liana	liana	NOUN
bionys-641	262	10	et	et	PROPN
bionys-641	262	11	al	al	PROPN
bionys-641	262	12	.	.	PUNCT
bionys-641	263	1	●	●	PUNCT
bionys-641	263	2	cell	cell	NOUN
bionys-641	263	3	deaths	death	NOUN
bionys-641	263	4	and	and	CCONJ
bionys-641	263	5	their	their	PRON
bionys-641	263	6	associated	associate	VERB
bionys-641	263	7	mechanisms	mechanism	NOUN
bionys-641	263	8	systems	system	NOUN
bionys-641	263	9	,	,	PUNCT
bionys-641	263	10	and	and	CCONJ
bionys-641	263	11	eventually	eventually	ADV
bionys-641	263	12	colonize	colonize	VERB
bionys-641	263	13	far	far	ADV
bionys-641	263	14	-	-	PUNCT
bionys-641	263	15	off	off	ADP
bionys-641	263	16	locations	location	NOUN
bionys-641	263	17	to	to	PART
bionys-641	263	18	develop	develop	VERB
bionys-641	263	19	secondary	secondary	ADJ
bionys-641	263	20	tumors	tumor	NOUN
bionys-641	263	21	(	(	PUNCT
bionys-641	263	22	zhao	zhao	X
bionys-641	263	23	et	et	PROPN
bionys-641	263	24	al	al	PROPN
bionys-641	263	25	.	.	PROPN
bionys-641	263	26	,	,	PUNCT
bionys-641	263	27	2014	2014	NUM
bionys-641	263	28	)	)	PUNCT
bionys-641	263	29	.	.	PUNCT
bionys-641	264	1	like	like	ADP
bionys-641	264	2	apoptosis	apoptosis	NOUN
bionys-641	264	3	,	,	PUNCT
bionys-641	264	4	anoikis	anoikis	PROPN
bionys-641	264	5	is	be	AUX
bionys-641	264	6	a	a	DET
bionys-641	264	7	process	process	NOUN
bionys-641	264	8	marked	mark	VERB
bionys-641	264	9	by	by	ADP
bionys-641	264	10	cellular	cellular	ADJ
bionys-641	264	11	and	and	CCONJ
bionys-641	264	12	molecular	molecular	ADJ
bionys-641	264	13	alterations	alteration	NOUN
bionys-641	264	14	,	,	PUNCT
bionys-641	264	15	including	include	VERB
bionys-641	264	16	membrane	membrane	NOUN
bionys-641	264	17	blebbing	blebbing	NOUN
bionys-641	264	18	,	,	PUNCT
bionys-641	264	19	chromatin	chromatin	NOUN
bionys-641	264	20	condensation	condensation	NOUN
bionys-641	264	21	,	,	PUNCT
bionys-641	264	22	dna	dna	NOUN
bionys-641	264	23	fragmentation	fragmentation	NOUN
bionys-641	264	24	,	,	PUNCT
bionys-641	264	25	and	and	CCONJ
bionys-641	264	26	caspase	caspase	NOUN
bionys-641	264	27	activation	activation	NOUN
bionys-641	264	28	.	.	PUNCT
bionys-641	265	1	these	these	DET
bionys-641	265	2	processes	process	NOUN
bionys-641	265	3	result	result	VERB
bionys-641	265	4	in	in	ADP
bionys-641	265	5	the	the	DET
bionys-641	265	6	methodical	methodical	ADJ
bionys-641	265	7	breakdown	breakdown	NOUN
bionys-641	265	8	and	and	CCONJ
bionys-641	265	9	elimination	elimination	NOUN
bionys-641	265	10	of	of	ADP
bionys-641	265	11	the	the	DET
bionys-641	265	12	cell	cell	NOUN
bionys-641	265	13	without	without	ADP
bionys-641	265	14	causing	cause	VERB
bionys-641	265	15	an	an	DET
bionys-641	265	16	inflammatory	inflammatory	ADJ
bionys-641	265	17	reaction	reaction	NOUN
bionys-641	265	18	(	(	PUNCT
bionys-641	265	19	park	park	NOUN
bionys-641	265	20	et	et	PROPN
bionys-641	265	21	al	al	PROPN
bionys-641	265	22	.	.	PROPN
bionys-641	265	23	,	,	PUNCT
bionys-641	265	24	2023	2023	NUM
bionys-641	265	25	)	)	PUNCT
bionys-641	265	26	.	.	PUNCT
bionys-641	266	1	oxeiptosis	oxeiptosis	NOUN
bionys-641	266	2	is	be	AUX
bionys-641	266	3	a	a	DET
bionys-641	266	4	form	form	NOUN
bionys-641	266	5	of	of	ADP
bionys-641	266	6	rcd	rcd	PROPN
bionys-641	266	7	induced	induce	VERB
bionys-641	266	8	by	by	ADP
bionys-641	266	9	oxygen	oxygen	NOUN
bionys-641	266	10	radicals	radical	NOUN
bionys-641	266	11	.	.	PUNCT
bionys-641	267	1	it	it	PRON
bionys-641	267	2	results	result	VERB
bionys-641	267	3	from	from	ADP
bionys-641	267	4	the	the	DET
bionys-641	267	5	activation	activation	NOUN
bionys-641	267	6	of	of	ADP
bionys-641	267	7	the	the	DET
bionys-641	267	8	keap-1	keap-1	PROPN
bionys-641	267	9	-	-	PUNCT
bionys-641	267	10	pgam5	pgam5	NOUN
bionys-641	267	11	-	-	PUNCT
bionys-641	267	12	aifm1	aifm1	NOUN
bionys-641	267	13	pathway	pathway	NOUN
bionys-641	267	14	.	.	PUNCT
bionys-641	268	1	ozone	ozone	NOUN
bionys-641	268	2	or	or	CCONJ
bionys-641	268	3	h2o2	h2o2	NOUN
bionys-641	268	4	-	-	ADJ
bionys-641	268	5	induced	induced	ADJ
bionys-641	268	6	oxeiptosis	oxeiptosis	NOUN
bionys-641	268	7	does	do	AUX
bionys-641	268	8	not	not	PART
bionys-641	268	9	engage	engage	VERB
bionys-641	268	10	apoptotic	apoptotic	ADJ
bionys-641	268	11	or	or	CCONJ
bionys-641	268	12	pyroptotic	pyroptotic	ADJ
bionys-641	268	13	caspases	caspase	NOUN
bionys-641	268	14	,	,	PUNCT
bionys-641	268	15	necroptosis	necroptosis	NOUN
bionys-641	268	16	,	,	PUNCT
bionys-641	268	17	autophagy	autophagy	NOUN
bionys-641	268	18	,	,	PUNCT
bionys-641	268	19	or	or	CCONJ
bionys-641	268	20	ferroptosis	ferroptosis	NOUN
bionys-641	268	21	(	(	PUNCT
bionys-641	268	22	holze	holze	NOUN
bionys-641	268	23	et	et	PROPN
bionys-641	268	24	al	al	PROPN
bionys-641	268	25	.	.	PROPN
bionys-641	268	26	,	,	PUNCT
bionys-641	268	27	2018	2018	NUM
bionys-641	268	28	)	)	PUNCT
bionys-641	268	29	.	.	PUNCT
bionys-641	269	1	the	the	DET
bionys-641	269	2	keap1nfe2l2	keap1nfe2l2	PROPN
bionys-641	269	3	pathway	pathway	NOUN
bionys-641	269	4	is	be	AUX
bionys-641	269	5	recognized	recognize	VERB
bionys-641	269	6	for	for	ADP
bionys-641	269	7	facilitating	facilitate	VERB
bionys-641	269	8	cytoprotective	cytoprotective	ADJ
bionys-641	269	9	responses	response	NOUN
bionys-641	269	10	to	to	PART
bionys-641	269	11	oxidative	oxidative	ADJ
bionys-641	269	12	stress	stress	NOUN
bionys-641	269	13	.	.	PUNCT
bionys-641	270	1	active	active	ADJ
bionys-641	270	2	keap1	keap1	NOUN
bionys-641	270	3	facilitates	facilitate	VERB
bionys-641	270	4	h2o2	h2o2	ADV
bionys-641	270	5	-	-	ADJ
bionys-641	270	6	induced	induced	ADJ
bionys-641	270	7	oxeiptosis	oxeiptosis	NOUN
bionys-641	270	8	through	through	ADP
bionys-641	270	9	a	a	DET
bionys-641	270	10	mechanism	mechanism	NOUN
bionys-641	270	11	involving	involve	VERB
bionys-641	270	12	pgam5	pgam5	NOUN
bionys-641	270	13	,	,	PUNCT
bionys-641	270	14	a	a	DET
bionys-641	270	15	mitochondrial	mitochondrial	ADJ
bionys-641	270	16	serine	serine	NOUN
bionys-641	270	17	-	-	PUNCT
bionys-641	270	18	threonine	threonine	ADJ
bionys-641	270	19	phosphatase	phosphatase	NOUN
bionys-641	270	20	that	that	PRON
bionys-641	270	21	dephosphorylates	dephosphorylate	VERB
bionys-641	270	22	aifm1	aifm1	PROPN
bionys-641	270	23	at	at	ADP
bionys-641	270	24	ser116	ser116	PROPN
bionys-641	270	25	(	(	PUNCT
bionys-641	270	26	holze	holze	PROPN
bionys-641	270	27	et	et	PROPN
bionys-641	270	28	al	al	PROPN
bionys-641	270	29	.	.	PROPN
bionys-641	270	30	,	,	PUNCT
bionys-641	270	31	2018	2018	NUM
bionys-641	270	32	;	;	PUNCT
bionys-641	270	33	tang	tang	X
bionys-641	270	34	et	et	PROPN
bionys-641	270	35	al	al	PROPN
bionys-641	270	36	.	.	PROPN
bionys-641	270	37	,	,	PUNCT
bionys-641	270	38	2019	2019	NUM
bionys-641	270	39	)	)	PUNCT
bionys-641	270	40	.	.	PUNCT
bionys-641	271	1	therapeutic	therapeutic	ADJ
bionys-641	271	2	implications	implication	NOUN
bionys-641	271	3	the	the	DET
bionys-641	271	4	unraveling	unraveling	NOUN
bionys-641	271	5	of	of	ADP
bionys-641	271	6	the	the	DET
bionys-641	271	7	molecular	molecular	ADJ
bionys-641	271	8	processes	process	NOUN
bionys-641	271	9	governing	govern	VERB
bionys-641	271	10	rcd	rcd	PROPN
bionys-641	271	11	has	have	AUX
bionys-641	271	12	reshaped	reshape	VERB
bionys-641	271	13	medication	medication	NOUN
bionys-641	271	14	development	development	NOUN
bionys-641	271	15	,	,	PUNCT
bionys-641	271	16	shifting	shift	VERB
bionys-641	271	17	from	from	ADP
bionys-641	271	18	broad	broad	ADJ
bionys-641	271	19	cytotoxic	cytotoxic	ADJ
bionys-641	271	20	drugs	drug	NOUN
bionys-641	271	21	to	to	ADP
bionys-641	271	22	personalized	personalized	ADJ
bionys-641	271	23	therapies	therapy	NOUN
bionys-641	271	24	designed	design	VERB
bionys-641	271	25	to	to	PART
bionys-641	271	26	modulate	modulate	VERB
bionys-641	271	27	certain	certain	ADJ
bionys-641	271	28	cell	cell	NOUN
bionys-641	271	29	death	death	NOUN
bionys-641	271	30	pathways	pathway	NOUN
bionys-641	271	31	.	.	PUNCT
bionys-641	272	1	this	this	DET
bionys-641	272	2	approach	approach	NOUN
bionys-641	272	3	could	could	AUX
bionys-641	272	4	effectively	effectively	ADV
bionys-641	272	5	eliminate	eliminate	VERB
bionys-641	272	6	malignant	malignant	ADJ
bionys-641	272	7	cells	cell	NOUN
bionys-641	272	8	,	,	PUNCT
bionys-641	272	9	such	such	ADJ
bionys-641	272	10	as	as	ADP
bionys-641	272	11	cancer	cancer	NOUN
bionys-641	272	12	cells	cell	NOUN
bionys-641	272	13	,	,	PUNCT
bionys-641	272	14	or	or	CCONJ
bionys-641	272	15	prevent	prevent	VERB
bionys-641	272	16	cell	cell	NOUN
bionys-641	272	17	death	death	NOUN
bionys-641	272	18	when	when	SCONJ
bionys-641	272	19	it	it	PRON
bionys-641	272	20	is	be	AUX
bionys-641	272	21	inappropriate	inappropriate	ADJ
bionys-641	272	22	,	,	PUNCT
bionys-641	272	23	as	as	SCONJ
bionys-641	272	24	shown	show	VERB
bionys-641	272	25	in	in	ADP
bionys-641	272	26	neurodegenerative	neurodegenerative	ADJ
bionys-641	272	27	and	and	CCONJ
bionys-641	272	28	inflammatory	inflammatory	ADJ
bionys-641	272	29	illnesses	illness	NOUN
bionys-641	272	30	.	.	PUNCT
bionys-641	273	1	the	the	DET
bionys-641	273	2	evasion	evasion	NOUN
bionys-641	273	3	of	of	ADP
bionys-641	273	4	apoptosis	apoptosis	NOUN
bionys-641	273	5	is	be	AUX
bionys-641	273	6	a	a	DET
bionys-641	273	7	hallmark	hallmark	NOUN
bionys-641	273	8	of	of	ADP
bionys-641	273	9	cancer	cancer	NOUN
bionys-641	273	10	,	,	PUNCT
bionys-641	273	11	enabling	enable	VERB
bionys-641	273	12	tumor	tumor	NOUN
bionys-641	273	13	cells	cell	NOUN
bionys-641	273	14	to	to	PART
bionys-641	273	15	endure	endure	VERB
bionys-641	273	16	stress	stress	NOUN
bionys-641	273	17	associated	associate	VERB
bionys-641	273	18	with	with	ADP
bionys-641	273	19	the	the	DET
bionys-641	273	20	disease	disease	NOUN
bionys-641	273	21	and	and	CCONJ
bionys-641	273	22	resist	resist	VERB
bionys-641	273	23	therapeutic	therapeutic	ADJ
bionys-641	273	24	interventions	intervention	NOUN
bionys-641	273	25	(	(	PUNCT
bionys-641	273	26	mirzayans	mirzayan	NOUN
bionys-641	273	27	,	,	PUNCT
bionys-641	273	28	2024	2024	NUM
bionys-641	273	29	)	)	PUNCT
bionys-641	273	30	.	.	PUNCT
bionys-641	274	1	a	a	DET
bionys-641	274	2	common	common	ADJ
bionys-641	274	3	method	method	NOUN
bionys-641	274	4	for	for	ADP
bionys-641	274	5	this	this	DET
bionys-641	274	6	evasion	evasion	NOUN
bionys-641	274	7	is	be	AUX
bionys-641	274	8	the	the	DET
bionys-641	274	9	overexpression	overexpression	NOUN
bionys-641	274	10	of	of	ADP
bionys-641	274	11	anti	anti	ADJ
bionys-641	274	12	-	-	ADJ
bionys-641	274	13	apoptotic	apoptotic	ADJ
bionys-641	274	14	proteins	protein	NOUN
bionys-641	274	15	from	from	ADP
bionys-641	274	16	the	the	DET
bionys-641	274	17	bcl-2	bcl-2	NOUN
bionys-641	274	18	group	group	NOUN
bionys-641	274	19	.	.	PUNCT
bionys-641	275	1	this	this	DET
bionys-641	275	2	understanding	understanding	NOUN
bionys-641	275	3	led	lead	VERB
bionys-641	275	4	to	to	ADP
bionys-641	275	5	the	the	DET
bionys-641	275	6	development	development	NOUN
bionys-641	275	7	of	of	ADP
bionys-641	275	8	a	a	DET
bionys-641	275	9	class	class	NOUN
bionys-641	275	10	of	of	ADP
bionys-641	275	11	medications	medication	NOUN
bionys-641	275	12	known	know	VERB
bionys-641	275	13	as	as	ADP
bionys-641	275	14	„	„	PUNCT
bionys-641	275	15	bh3	bh3	PROPN
bionys-641	275	16	mimetics	mimetic	NOUN
bionys-641	275	17	”	"	PUNCT
bionys-641	275	18	,	,	PUNCT
bionys-641	275	19	which	which	PRON
bionys-641	275	20	are	be	AUX
bionys-641	275	21	small	small	ADJ
bionys-641	275	22	compounds	compound	NOUN
bionys-641	275	23	designed	design	VERB
bionys-641	275	24	to	to	PART
bionys-641	275	25	mimic	mimic	VERB
bionys-641	275	26	the	the	DET
bionys-641	275	27	bh3	bh3	NOUN
bionys-641	275	28	-	-	PUNCT
bionys-641	275	29	only	only	ADV
bionys-641	275	30	pro	pro	ADJ
bionys-641	275	31	-	-	ADJ
bionys-641	275	32	apoptotic	apoptotic	ADJ
bionys-641	275	33	proteins	protein	NOUN
bionys-641	275	34	that	that	PRON
bionys-641	275	35	naturally	naturally	ADV
bionys-641	275	36	counteract	counteract	VERB
bionys-641	275	37	their	their	PRON
bionys-641	275	38	anti	anti	ADJ
bionys-641	275	39	-	-	ADJ
bionys-641	275	40	apoptotic	apoptotic	ADJ
bionys-641	275	41	counterparts	counterpart	NOUN
bionys-641	275	42	(	(	PUNCT
bionys-641	275	43	hassig	hassig	X
bionys-641	275	44	et	et	PROPN
bionys-641	275	45	al	al	PROPN
bionys-641	275	46	.	.	PROPN
bionys-641	275	47	,	,	PUNCT
bionys-641	275	48	2014	2014	NUM
bionys-641	275	49	;	;	PUNCT
bionys-641	275	50	fulda	fulda	NOUN
bionys-641	275	51	,	,	PUNCT
bionys-641	275	52	2015	2015	NUM
bionys-641	275	53	)	)	PUNCT
bionys-641	275	54	.	.	PUNCT
bionys-641	276	1	a	a	DET
bionys-641	276	2	drug	drug	NOUN
bionys-641	276	3	,	,	PUNCT
bionys-641	276	4	venetoclax	venetoclax	NOUN
bionys-641	276	5	,	,	PUNCT
bionys-641	276	6	the	the	DET
bionys-641	276	7	inaugural	inaugural	ADJ
bionys-641	276	8	bcl-2	bcl-2	PUNCT
bionys-641	276	9	inhibitor	inhibitor	NOUN
bionys-641	276	10	of	of	ADP
bionys-641	276	11	its	its	PRON
bionys-641	276	12	type	type	NOUN
bionys-641	276	13	,	,	PUNCT
bionys-641	276	14	represents	represent	VERB
bionys-641	276	15	a	a	DET
bionys-641	276	16	significant	significant	ADJ
bionys-641	276	17	advancement	advancement	NOUN
bionys-641	276	18	in	in	ADP
bionys-641	276	19	this	this	DET
bionys-641	276	20	domain	domain	NOUN
bionys-641	276	21	,	,	PUNCT
bionys-641	276	22	particularly	particularly	ADV
bionys-641	276	23	for	for	ADP
bionys-641	276	24	treating	treat	VERB
bionys-641	276	25	numerous	numerous	ADJ
bionys-641	276	26	hematologic	hematologic	ADJ
bionys-641	276	27	malignancies	malignancy	NOUN
bionys-641	276	28	.	.	PUNCT
bionys-641	277	1	in	in	ADP
bionys-641	277	2	chronic	chronic	ADJ
bionys-641	277	3	lymphocytic	lymphocytic	ADJ
bionys-641	277	4	leukemia	leukemia	NOUN
bionys-641	277	5	(	(	PUNCT
bionys-641	277	6	cll	cll	PROPN
bionys-641	277	7	)	)	PUNCT
bionys-641	277	8	,	,	PUNCT
bionys-641	277	9	particularly	particularly	ADV
bionys-641	277	10	in	in	ADP
bionys-641	277	11	individuals	individual	NOUN
bionys-641	277	12	with	with	ADP
bionys-641	277	13	the	the	DET
bionys-641	277	14	highrisk	highrisk	NOUN
bionys-641	277	15	17p	17p	NOUN
bionys-641	277	16	deletion	deletion	NOUN
bionys-641	277	17	who	who	PRON
bionys-641	277	18	often	often	ADV
bionys-641	277	19	demonstrate	demonstrate	VERB
bionys-641	277	20	resistance	resistance	NOUN
bionys-641	277	21	to	to	ADP
bionys-641	277	22	conventional	conventional	ADJ
bionys-641	277	23	chemoimmunotherapy	chemoimmunotherapy	NOUN
bionys-641	277	24	,	,	PUNCT
bionys-641	277	25	venetoclax	venetoclax	NOUN
bionys-641	277	26	has	have	AUX
bionys-641	277	27	exhibited	exhibit	VERB
bionys-641	277	28	substantial	substantial	ADJ
bionys-641	277	29	and	and	CCONJ
bionys-641	277	30	enduring	enduring	ADJ
bionys-641	277	31	results	result	NOUN
bionys-641	277	32	(	(	PUNCT
bionys-641	277	33	stilgenbauer	stilgenbauer	NOUN
bionys-641	277	34	et	et	PROPN
bionys-641	277	35	al	al	PROPN
bionys-641	277	36	.	.	PROPN
bionys-641	277	37	,	,	PUNCT
bionys-641	277	38	2016	2016	NUM
bionys-641	277	39	)	)	PUNCT
bionys-641	277	40	.	.	PUNCT
bionys-641	278	1	similarly	similarly	ADV
bionys-641	278	2	,	,	PUNCT
bionys-641	278	3	in	in	ADP
bionys-641	278	4	acute	acute	ADJ
bionys-641	278	5	myeloid	myeloid	NOUN
bionys-641	278	6	leukemia	leukemia	NOUN
bionys-641	278	7	(	(	PUNCT
bionys-641	278	8	aml	aml	PROPN
bionys-641	278	9	)	)	PUNCT
bionys-641	278	10	,	,	PUNCT
bionys-641	278	11	the	the	DET
bionys-641	278	12	combination	combination	NOUN
bionys-641	278	13	of	of	ADP
bionys-641	278	14	venetoclax	venetoclax	NOUN
bionys-641	278	15	with	with	ADP
bionys-641	278	16	hypomethylating	hypomethylate	VERB
bionys-641	278	17	drugs	drug	NOUN
bionys-641	278	18	(	(	PUNCT
bionys-641	278	19	e.g.	e.g.	ADV
bionys-641	278	20	,	,	PUNCT
bionys-641	278	21	azacytidine	azacytidine	NOUN
bionys-641	278	22	and	and	CCONJ
bionys-641	278	23	decitabine	decitabine	NOUN
bionys-641	278	24	)	)	PUNCT
bionys-641	278	25	has	have	AUX
bionys-641	278	26	become	become	VERB
bionys-641	278	27	a	a	DET
bionys-641	278	28	new	new	ADJ
bionys-641	278	29	standard	standard	NOUN
bionys-641	278	30	of	of	ADP
bionys-641	278	31	care	care	NOUN
bionys-641	278	32	(	(	PUNCT
bionys-641	278	33	ucciero	ucciero	PROPN
bionys-641	278	34	et	et	PROPN
bionys-641	278	35	al	al	PROPN
bionys-641	278	36	.	.	PROPN
bionys-641	278	37	,	,	PUNCT
bionys-641	278	38	2023	2023	NUM
bionys-641	278	39	)	)	PUNCT
bionys-641	278	40	.	.	PUNCT
bionys-641	279	1	inhibiting	inhibit	VERB
bionys-641	279	2	cell	cell	NOUN
bionys-641	279	3	death	death	NOUN
bionys-641	279	4	is	be	AUX
bionys-641	279	5	the	the	DET
bionys-641	279	6	primary	primary	ADJ
bionys-641	279	7	approach	approach	NOUN
bionys-641	279	8	to	to	ADP
bionys-641	279	9	treating	treat	VERB
bionys-641	279	10	numerous	numerous	ADJ
bionys-641	279	11	chronic	chronic	ADJ
bionys-641	279	12	inflammatory	inflammatory	ADJ
bionys-641	279	13	and	and	CCONJ
bionys-641	279	14	neurodegenerative	neurodegenerative	ADJ
bionys-641	279	15	disorders	disorder	NOUN
bionys-641	279	16	.	.	PUNCT
bionys-641	280	1	halting	halting	ADJ
bionys-641	280	2	necroptosis	necroptosis	NOUN
bionys-641	280	3	is	be	AUX
bionys-641	280	4	thought	think	VERB
bionys-641	280	5	to	to	PART
bionys-641	280	6	mitigate	mitigate	VERB
bionys-641	280	7	tissue	tissue	NOUN
bionys-641	280	8	damage	damage	NOUN
bionys-641	280	9	and	and	CCONJ
bionys-641	280	10	disease	disease	NOUN
bionys-641	280	11	progression	progression	NOUN
bionys-641	280	12	in	in	ADP
bionys-641	280	13	this	this	DET
bionys-641	280	14	context	context	NOUN
bionys-641	280	15	.	.	PUNCT
bionys-641	281	1	ripk1	ripk1	NOUN
bionys-641	281	2	,	,	PUNCT
bionys-641	281	3	the	the	DET
bionys-641	281	4	primary	primary	ADJ
bionys-641	281	5	kinase	kinase	NOUN
bionys-641	281	6	in	in	ADP
bionys-641	281	7	the	the	DET
bionys-641	281	8	system	system	NOUN
bionys-641	281	9	,	,	PUNCT
bionys-641	281	10	has	have	AUX
bionys-641	281	11	been	be	AUX
bionys-641	281	12	the	the	DET
bionys-641	281	13	principal	principal	ADJ
bionys-641	281	14	focus	focus	NOUN
bionys-641	281	15	of	of	ADP
bionys-641	281	16	pharmacological	pharmacological	ADJ
bionys-641	281	17	development	development	NOUN
bionys-641	281	18	.	.	PUNCT
bionys-641	282	1	the	the	DET
bionys-641	282	2	discovery	discovery	NOUN
bionys-641	282	3	of	of	ADP
bionys-641	282	4	necrostatin-1	necrostatin-1	NUM
bionys-641	282	5	,	,	PUNCT
bionys-641	282	6	a	a	DET
bionys-641	282	7	small	small	ADJ
bionys-641	282	8	-	-	PUNCT
bionys-641	282	9	molecule	molecule	NOUN
bionys-641	282	10	inhibitor	inhibitor	NOUN
bionys-641	282	11	of	of	ADP
bionys-641	282	12	ripk1	ripk1	NOUN
bionys-641	282	13	,	,	PUNCT
bionys-641	282	14	represented	represent	VERB
bionys-641	282	15	the	the	DET
bionys-641	282	16	first	first	ADJ
bionys-641	282	17	pharmacological	pharmacological	ADJ
bionys-641	282	18	instrument	instrument	NOUN
bionys-641	282	19	to	to	PART
bionys-641	282	20	demonstrate	demonstrate	VERB
bionys-641	282	21	the	the	DET
bionys-641	282	22	therapeutic	therapeutic	ADJ
bionys-641	282	23	effectiveness	effectiveness	NOUN
bionys-641	282	24	of	of	ADP
bionys-641	282	25	necroptosis	necroptosis	NOUN
bionys-641	282	26	inhibition	inhibition	NOUN
bionys-641	282	27	in	in	ADP
bionys-641	282	28	many	many	ADJ
bionys-641	282	29	preclinical	preclinical	ADJ
bionys-641	282	30	illness	illness	NOUN
bionys-641	282	31	settings	setting	NOUN
bionys-641	282	32	(	(	PUNCT
bionys-641	282	33	vandenabeele	vandenabeele	NOUN
bionys-641	282	34	et	et	PROPN
bionys-641	282	35	al	al	PROPN
bionys-641	282	36	.	.	PROPN
bionys-641	282	37	,	,	PUNCT
bionys-641	282	38	2013	2013	NUM
bionys-641	282	39	)	)	PUNCT
bionys-641	282	40	.	.	PUNCT
bionys-641	283	1	subsequently	subsequently	ADV
bionys-641	283	2	,	,	PUNCT
bionys-641	283	3	more	more	ADV
bionys-641	283	4	potent	potent	ADJ
bionys-641	283	5	and	and	CCONJ
bionys-641	283	6	specific	specific	ADJ
bionys-641	283	7	next	next	ADJ
bionys-641	283	8	-	-	PUNCT
bionys-641	283	9	generation	generation	NOUN
bionys-641	283	10	ripk1	ripk1	NOUN
bionys-641	283	11	inhibitors	inhibitor	NOUN
bionys-641	283	12	with	with	ADP
bionys-641	283	13	enhanced	enhanced	ADJ
bionys-641	283	14	pharmacological	pharmacological	ADJ
bionys-641	283	15	characteristics	characteristic	NOUN
bionys-641	283	16	were	be	AUX
bionys-641	283	17	developed	develop	VERB
bionys-641	283	18	and	and	CCONJ
bionys-641	283	19	evaluated	evaluate	VERB
bionys-641	283	20	in	in	ADP
bionys-641	283	21	clinical	clinical	ADJ
bionys-641	283	22	studies	study	NOUN
bionys-641	283	23	.	.	PUNCT
bionys-641	284	1	several	several	ADJ
bionys-641	284	2	drugs	drug	NOUN
bionys-641	284	3	,	,	PUNCT
bionys-641	284	4	including	include	VERB
bionys-641	284	5	gsk2982772	gsk2982772	NOUN
bionys-641	284	6	,	,	PUNCT
bionys-641	284	7	sar443060	sar443060	NOUN
bionys-641	284	8	(	(	PUNCT
bionys-641	284	9	dnl747	dnl747	PROPN
bionys-641	284	10	)	)	PUNCT
bionys-641	284	11	,	,	PUNCT
bionys-641	284	12	and	and	CCONJ
bionys-641	284	13	sar443820	sar443820	NOUN
bionys-641	284	14	(	(	PUNCT
bionys-641	284	15	dnl788	dnl788	PROPN
bionys-641	284	16	)	)	PUNCT
bionys-641	284	17	,	,	PUNCT
bionys-641	284	18	have	have	AUX
bionys-641	284	19	been	be	AUX
bionys-641	284	20	evaluated	evaluate	VERB
bionys-641	284	21	in	in	ADP
bionys-641	284	22	phase	phase	NOUN
bionys-641	284	23	i	i	PRON
bionys-641	284	24	and	and	CCONJ
bionys-641	284	25	ii	ii	NOUN
bionys-641	284	26	trials	trial	NOUN
bionys-641	284	27	for	for	ADP
bionys-641	284	28	various	various	ADJ
bionys-641	284	29	neurodegenerative	neurodegenerative	ADJ
bionys-641	284	30	and	and	CCONJ
bionys-641	284	31	inflammatory	inflammatory	ADJ
bionys-641	284	32	illnesses	illness	NOUN
bionys-641	284	33	(	(	PUNCT
bionys-641	284	34	vissers	visser	NOUN
bionys-641	284	35	et	et	PROPN
bionys-641	284	36	al	al	PROPN
bionys-641	284	37	.	.	PROPN
bionys-641	284	38	,	,	PUNCT
bionys-641	284	39	2022	2022	NUM
bionys-641	284	40	;	;	PUNCT
bionys-641	284	41	hincelin	hincelin	PROPN
bionys-641	284	42	-	-	PUNCT
bionys-641	284	43	mery	mery	PROPN
bionys-641	284	44	et	et	PROPN
bionys-641	284	45	al	al	PROPN
bionys-641	284	46	.	.	PROPN
bionys-641	284	47	,	,	PUNCT
bionys-641	284	48	2024	2024	NUM
bionys-641	284	49	;	;	PUNCT
bionys-641	284	50	gonen	gonen	PROPN
bionys-641	284	51	et	et	PROPN
bionys-641	284	52	al	al	PROPN
bionys-641	284	53	.	.	PROPN
bionys-641	284	54	,	,	PUNCT
bionys-641	284	55	2025	2025	NUM
bionys-641	284	56	)	)	PUNCT
bionys-641	284	57	.	.	PUNCT
bionys-641	285	1	although	although	SCONJ
bionys-641	285	2	these	these	DET
bionys-641	285	3	drugs	drug	NOUN
bionys-641	285	4	demonstrated	demonstrate	VERB
bionys-641	285	5	a	a	DET
bionys-641	285	6	favorable	favorable	ADJ
bionys-641	285	7	safety	safety	NOUN
bionys-641	285	8	profile	profile	NOUN
bionys-641	285	9	,	,	PUNCT
bionys-641	285	10	its	its	PRON
bionys-641	285	11	clinical	clinical	ADJ
bionys-641	285	12	application	application	NOUN
bionys-641	285	13	has	have	AUX
bionys-641	285	14	been	be	AUX
bionys-641	285	15	challenging	challenge	VERB
bionys-641	285	16	due	due	ADJ
bionys-641	285	17	to	to	ADP
bionys-641	285	18	the	the	DET
bionys-641	285	19	lack	lack	NOUN
bionys-641	285	20	of	of	ADP
bionys-641	285	21	significant	significant	ADJ
bionys-641	285	22	medical	medical	ADJ
bionys-641	285	23	benefit	benefit	NOUN
bionys-641	285	24	.	.	PUNCT
bionys-641	286	1	inducing	induce	VERB
bionys-641	286	2	ferroptosis	ferroptosis	NOUN
bionys-641	286	3	in	in	ADP
bionys-641	286	4	cancer	cancer	NOUN
bionys-641	286	5	highlights	highlight	NOUN
bionys-641	286	6	a	a	DET
bionys-641	286	7	unique	unique	ADJ
bionys-641	286	8	therapeutic	therapeutic	ADJ
bionys-641	286	9	paradox	paradox	NOUN
bionys-641	286	10	:	:	PUNCT
bionys-641	286	11	the	the	DET
bionys-641	286	12	same	same	ADJ
bionys-641	286	13	procedure	procedure	NOUN
bionys-641	286	14	that	that	PRON
bionys-641	286	15	kills	kill	VERB
bionys-641	286	16	cancer	cancer	NOUN
bionys-641	286	17	cells	cell	NOUN
bionys-641	286	18	can	can	AUX
bionys-641	286	19	also	also	ADV
bionys-641	286	20	be	be	AUX
bionys-641	286	21	inhibited	inhibit	VERB
bionys-641	286	22	to	to	PART
bionys-641	286	23	preserve	preserve	VERB
bionys-641	286	24	neurons	neuron	NOUN
bionys-641	286	25	,	,	PUNCT
bionys-641	286	26	highlighting	highlight	VERB
bionys-641	286	27	its	its	PRON
bionys-641	286	28	context	context	NOUN
bionys-641	286	29	-	-	PUNCT
bionys-641	286	30	dependent	dependent	ADJ
bionys-641	286	31	role	role	NOUN
bionys-641	286	32	in	in	ADP
bionys-641	286	33	disease	disease	NOUN
bionys-641	286	34	.	.	PUNCT
bionys-641	287	1	as	as	ADP
bionys-641	287	2	a	a	DET
bionys-641	287	3	result	result	NOUN
bionys-641	287	4	,	,	PUNCT
bionys-641	287	5	multiple	multiple	ADJ
bionys-641	287	6	preclinical	preclinical	ADJ
bionys-641	287	7	studies	study	NOUN
bionys-641	287	8	have	have	AUX
bionys-641	287	9	demonstrated	demonstrate	VERB
bionys-641	287	10	the	the	DET
bionys-641	287	11	significant	significant	ADJ
bionys-641	287	12	efficacy	efficacy	NOUN
bionys-641	287	13	of	of	ADP
bionys-641	287	14	tool	tool	NOUN
bionys-641	287	15	compounds	compound	VERB
bionys-641	287	16	like	like	ADP
bionys-641	287	17	erastin	erastin	NOUN
bionys-641	287	18	and	and	CCONJ
bionys-641	287	19	rsl3	rsl3	PROPN
bionys-641	287	20	in	in	ADP
bionys-641	287	21	diverse	diverse	ADJ
bionys-641	287	22	cancer	cancer	NOUN
bionys-641	287	23	types	type	NOUN
bionys-641	287	24	(	(	PUNCT
bionys-641	287	25	ghoochani	ghoochani	X
bionys-641	287	26	et	et	PROPN
bionys-641	287	27	al	al	PROPN
bionys-641	287	28	.	.	PROPN
bionys-641	287	29	,	,	PUNCT
bionys-641	287	30	2021	2021	NUM
bionys-641	287	31	)	)	PUNCT
bionys-641	287	32	.	.	PUNCT
bionys-641	288	1	meanwhile	meanwhile	ADV
bionys-641	288	2	,	,	PUNCT
bionys-641	288	3	several	several	ADJ
bionys-641	288	4	potent	potent	ADJ
bionys-641	288	5	ferroptosis	ferroptosis	NOUN
bionys-641	288	6	inhibitors	inhibitor	NOUN
bionys-641	288	7	,	,	PUNCT
bionys-641	288	8	such	such	ADJ
bionys-641	288	9	as	as	ADP
bionys-641	288	10	the	the	DET
bionys-641	288	11	radical	radical	ADJ
bionys-641	288	12	-	-	PUNCT
bionys-641	288	13	trapping	trap	VERB
bionys-641	288	14	antioxidants	antioxidant	NOUN
bionys-641	288	15	ferrostatin-1	ferrostatin-1	NUM
bionys-641	288	16	and	and	CCONJ
bionys-641	288	17	liproxstatin-1	liproxstatin-1	NOUN
bionys-641	288	18	,	,	PUNCT
bionys-641	288	19	have	have	AUX
bionys-641	288	20	consistently	consistently	ADV
bionys-641	288	21	shown	show	VERB
bionys-641	288	22	advantageous	advantageous	ADJ
bionys-641	288	23	neuroprotective	neuroprotective	ADJ
bionys-641	288	24	effects	effect	NOUN
bionys-641	288	25	in	in	ADP
bionys-641	288	26	animal	animal	NOUN
bionys-641	288	27	models	model	NOUN
bionys-641	288	28	of	of	ADP
bionys-641	288	29	neurodegenerative	neurodegenerative	ADJ
bionys-641	288	30	diseases	disease	NOUN
bionys-641	288	31	(	(	PUNCT
bionys-641	288	32	zilka	zilka	NOUN
bionys-641	288	33	et	et	PROPN
bionys-641	288	34	al	al	PROPN
bionys-641	288	35	.	.	PROPN
bionys-641	288	36	,	,	PUNCT
bionys-641	288	37	2017	2017	NUM
bionys-641	288	38	)	)	PUNCT
bionys-641	288	39	.	.	PUNCT
bionys-641	289	1	the	the	DET
bionys-641	289	2	therapeutic	therapeutic	ADJ
bionys-641	289	3	challenge	challenge	NOUN
bionys-641	289	4	is	be	AUX
bionys-641	289	5	to	to	PART
bionys-641	289	6	develop	develop	VERB
bionys-641	289	7	ferroptosis	ferroptosis	NOUN
bionys-641	289	8	inhibitors	inhibitor	NOUN
bionys-641	289	9	capable	capable	ADJ
bionys-641	289	10	of	of	ADP
bionys-641	289	11	traversing	traverse	VERB
bionys-641	289	12	the	the	DET
bionys-641	289	13	blood	blood	NOUN
bionys-641	289	14	-	-	PUNCT
bionys-641	289	15	brain	brain	NOUN
bionys-641	289	16	barrier	barrier	NOUN
bionys-641	289	17	,	,	PUNCT
bionys-641	289	18	exhibiting	exhibit	VERB
bionys-641	289	19	high	high	ADJ
bionys-641	289	20	specificity	specificity	NOUN
bionys-641	289	21	,	,	PUNCT
bionys-641	289	22	and	and	CCONJ
bionys-641	289	23	possessing	possess	VERB
bionys-641	289	24	an	an	DET
bionys-641	289	25	extensive	extensive	ADJ
bionys-641	289	26	therapeutic	therapeutic	ADJ
bionys-641	289	27	window	window	NOUN
bionys-641	289	28	.	.	PUNCT
bionys-641	290	1	the	the	DET
bionys-641	290	2	summary	summary	NOUN
bionys-641	290	3	regarding	regard	VERB
bionys-641	290	4	cell	cell	NOUN
bionys-641	290	5	death	death	NOUN
bionys-641	290	6	targeting	target	VERB
bionys-641	290	7	to	to	PART
bionys-641	290	8	treat	treat	VERB
bionys-641	290	9	numerous	numerous	ADJ
bionys-641	290	10	diseases	disease	NOUN
bionys-641	290	11	is	be	AUX
bionys-641	290	12	available	available	ADJ
bionys-641	290	13	in	in	ADP
bionys-641	290	14	fig	fig	NOUN
bionys-641	290	15	.	.	PUNCT
bionys-641	291	1	3	3	X
bionys-641	291	2	.	.	NOUN
bionys-641	291	3	immunogenic	immunogenic	ADJ
bionys-641	291	4	cell	cell	NOUN
bionys-641	291	5	death	death	NOUN
bionys-641	291	6	and	and	CCONJ
bionys-641	291	7	anti	anti	ADJ
bionys-641	291	8	-	-	ADJ
bionys-641	291	9	tumor	tumor	ADJ
bionys-641	291	10	immune	immune	ADJ
bionys-641	291	11	response	response	NOUN
bionys-641	291	12	immunogenic	immunogenic	ADJ
bionys-641	291	13	cell	cell	NOUN
bionys-641	291	14	death	death	NOUN
bionys-641	291	15	(	(	PUNCT
bionys-641	291	16	icd	icd	PROPN
bionys-641	291	17	)	)	PUNCT
bionys-641	291	18	has	have	AUX
bionys-641	291	19	revolutionized	revolutionize	VERB
bionys-641	291	20	the	the	DET
bionys-641	291	21	fields	field	NOUN
bionys-641	291	22	of	of	ADP
bionys-641	291	23	cell	cell	NOUN
bionys-641	291	24	death	death	NOUN
bionys-641	291	25	and	and	CCONJ
bionys-641	291	26	immunology	immunology	NOUN
bionys-641	291	27	,	,	PUNCT
bionys-641	291	28	illustrating	illustrate	VERB
bionys-641	291	29	that	that	SCONJ
bionys-641	291	30	particular	particular	ADJ
bionys-641	291	31	forms	form	NOUN
bionys-641	291	32	of	of	ADP
bionys-641	291	33	rcd	rcd	PROPN
bionys-641	291	34	can	can	AUX
bionys-641	291	35	convert	convert	VERB
bionys-641	291	36	dying	die	VERB
bionys-641	291	37	tumor	tumor	NOUN
bionys-641	291	38	cells	cell	NOUN
bionys-641	291	39	into	into	ADP
bionys-641	291	40	a	a	DET
bionys-641	291	41	potent	potent	NOUN
bionys-641	291	42	in	in	ADP
bionys-641	291	43	situ	situ	ADJ
bionys-641	291	44	vaccine	vaccine	NOUN
bionys-641	291	45	capable	capable	ADJ
bionys-641	291	46	of	of	ADP
bionys-641	291	47	eliciting	elicit	VERB
bionys-641	291	48	a	a	DET
bionys-641	291	49	robust	robust	ADJ
bionys-641	291	50	and	and	CCONJ
bionys-641	291	51	enduring	enduring	ADJ
bionys-641	291	52	anti	anti	ADJ
bionys-641	291	53	-	-	ADJ
bionys-641	291	54	tumor	tumor	ADJ
bionys-641	291	55	immune	immune	ADJ
bionys-641	291	56	response	response	NOUN
bionys-641	291	57	.	.	PUNCT
bionys-641	292	1	this	this	DET
bionys-641	292	2	concept	concept	NOUN
bionys-641	292	3	is	be	AUX
bionys-641	292	4	now	now	ADV
bionys-641	292	5	integral	integral	ADJ
bionys-641	292	6	to	to	ADP
bionys-641	292	7	contemporary	contemporary	ADJ
bionys-641	292	8	cancer	cancer	NOUN
bionys-641	292	9	immunotherapy	immunotherapy	NOUN
bionys-641	292	10	.	.	PUNCT
bionys-641	293	1	biologica	biologica	PROPN
bionys-641	293	2	nyssana	nyssana	PROPN
bionys-641	293	3	●	●	PUNCT
bionys-641	293	4	16	16	NUM
bionys-641	293	5	(	(	PUNCT
bionys-641	293	6	2	2	NUM
bionys-641	293	7	)	)	PUNCT
bionys-641	293	8	december	december	PROPN
bionys-641	293	9	2025	2025	NUM
bionys-641	293	10	:	:	PUNCT
bionys-641	293	11	liana	liana	NOUN
bionys-641	293	12	et	et	PROPN
bionys-641	293	13	al	al	PROPN
bionys-641	293	14	.	.	PUNCT
bionys-641	294	1	●	●	PUNCT
bionys-641	294	2	cell	cell	NOUN
bionys-641	294	3	deaths	death	NOUN
bionys-641	294	4	and	and	CCONJ
bionys-641	294	5	their	their	PRON
bionys-641	294	6	associated	associate	VERB
bionys-641	294	7	mechanisms	mechanism	NOUN
bionys-641	294	8	an	an	DET
bionys-641	294	9	icd	icd	NOUN
bionys-641	294	10	is	be	AUX
bionys-641	294	11	a	a	DET
bionys-641	294	12	variant	variant	NOUN
bionys-641	294	13	of	of	ADP
bionys-641	294	14	rcd	rcd	PROPN
bionys-641	294	15	that	that	PRON
bionys-641	294	16	possesses	possess	VERB
bionys-641	294	17	sufficient	sufficient	ADJ
bionys-641	294	18	strength	strength	NOUN
bionys-641	294	19	to	to	PART
bionys-641	294	20	initiate	initiate	VERB
bionys-641	294	21	an	an	DET
bionys-641	294	22	adaptive	adaptive	ADJ
bionys-641	294	23	immune	immune	ADJ
bionys-641	294	24	response	response	NOUN
bionys-641	294	25	against	against	ADP
bionys-641	294	26	antigens	antigen	NOUN
bionys-641	294	27	derived	derive	VERB
bionys-641	294	28	from	from	ADP
bionys-641	294	29	necrotic	necrotic	ADJ
bionys-641	294	30	cells	cell	NOUN
bionys-641	294	31	.	.	PUNCT
bionys-641	295	1	the	the	DET
bionys-641	295	2	prompt	prompt	ADJ
bionys-641	295	3	release	release	NOUN
bionys-641	295	4	or	or	CCONJ
bionys-641	295	5	exposure	exposure	NOUN
bionys-641	295	6	of	of	ADP
bionys-641	295	7	a	a	DET
bionys-641	295	8	particular	particular	ADJ
bionys-641	295	9	collection	collection	NOUN
bionys-641	295	10	of	of	ADP
bionys-641	295	11	molecules	molecule	NOUN
bionys-641	295	12	known	know	VERB
bionys-641	295	13	as	as	SCONJ
bionys-641	295	14	damps	damp	VERB
bionys-641	295	15	confers	confer	NOUN
bionys-641	295	16	this	this	DET
bionys-641	295	17	immunogenicity	immunogenicity	NOUN
bionys-641	295	18	(	(	PUNCT
bionys-641	295	19	galluzzi	galluzzi	NOUN
bionys-641	295	20	et	et	PROPN
bionys-641	295	21	al	al	PROPN
bionys-641	295	22	.	.	PROPN
bionys-641	295	23	,	,	PUNCT
bionys-641	295	24	2020	2020	NUM
bionys-641	295	25	)	)	PUNCT
bionys-641	295	26	.	.	PUNCT
bionys-641	296	1	an	an	DET
bionys-641	296	2	identifiable	identifiable	ADJ
bionys-641	296	3	„	„	PUNCT
bionys-641	296	4	immunogenic	immunogenic	ADJ
bionys-641	296	5	triad	triad	NOUN
bionys-641	296	6	”	"	PUNCT
bionys-641	296	7	of	of	ADP
bionys-641	296	8	damps	damp	NOUN
bionys-641	296	9	is	be	AUX
bionys-641	296	10	considered	consider	VERB
bionys-641	296	11	the	the	DET
bionys-641	296	12	hallmark	hallmark	NOUN
bionys-641	296	13	of	of	ADP
bionys-641	296	14	genuine	genuine	ADJ
bionys-641	296	15	icd	icd	NOUN
bionys-641	296	16	.	.	PUNCT
bionys-641	297	1	these	these	PRON
bionys-641	297	2	damps	damps	AUX
bionys-641	297	3	initiate	initiate	VERB
bionys-641	297	4	a	a	DET
bionys-641	297	5	complex	complex	ADJ
bionys-641	297	6	immunological	immunological	ADJ
bionys-641	297	7	response	response	NOUN
bionys-641	297	8	that	that	PRON
bionys-641	297	9	transforms	transform	VERB
bionys-641	297	10	a	a	DET
bionys-641	297	11	tumor	tumor	NOUN
bionys-641	297	12	microenvironment	microenvironment	NOUN
bionys-641	297	13	(	(	PUNCT
bionys-641	297	14	tme	tme	NOUN
bionys-641	297	15	)	)	PUNCT
bionys-641	297	16	that	that	PRON
bionys-641	297	17	is	be	AUX
bionys-641	297	18	unresponsive	unresponsive	ADJ
bionys-641	297	19	to	to	ADP
bionys-641	297	20	the	the	DET
bionys-641	297	21	immune	immune	ADJ
bionys-641	297	22	system	system	NOUN
bionys-641	297	23	,	,	PUNCT
bionys-641	297	24	or	or	CCONJ
bionys-641	297	25	„	„	PUNCT
bionys-641	297	26	cold	cold	ADJ
bionys-641	297	27	”	"	PUNCT
bionys-641	297	28	,	,	PUNCT
bionys-641	297	29	into	into	ADP
bionys-641	297	30	an	an	DET
bionys-641	297	31	inflamed	inflamed	ADJ
bionys-641	297	32	or	or	CCONJ
bionys-641	297	33	„	„	PUNCT
bionys-641	297	34	hot	hot	ADJ
bionys-641	297	35	”	"	PUNCT
bionys-641	297	36	state	state	NOUN
bionys-641	297	37	,	,	PUNCT
bionys-641	297	38	facilitating	facilitate	VERB
bionys-641	297	39	the	the	DET
bionys-641	297	40	infiltration	infiltration	NOUN
bionys-641	297	41	of	of	ADP
bionys-641	297	42	activated	activate	VERB
bionys-641	297	43	antigen	antigen	NOUN
bionys-641	297	44	-	-	PUNCT
bionys-641	297	45	presenting	present	VERB
bionys-641	297	46	cells	cell	NOUN
bionys-641	297	47	(	(	PUNCT
bionys-641	297	48	apcs	apc	NOUN
bionys-641	297	49	)	)	PUNCT
bionys-641	297	50	and	and	CCONJ
bionys-641	297	51	effector	effector	NOUN
bionys-641	297	52	t	t	PROPN
bionys-641	297	53	cells	cell	NOUN
bionys-641	297	54	(	(	PUNCT
bionys-641	297	55	galluzzi	galluzzi	NOUN
bionys-641	297	56	et	et	PROPN
bionys-641	297	57	al	al	PROPN
bionys-641	297	58	.	.	PROPN
bionys-641	297	59	,	,	PUNCT
bionys-641	297	60	2020	2020	NUM
bionys-641	297	61	;	;	PUNCT
bionys-641	297	62	solari	solari	PROPN
bionys-641	297	63	et	et	PROPN
bionys-641	297	64	al	al	PROPN
bionys-641	297	65	.	.	PROPN
bionys-641	297	66	,	,	PUNCT
bionys-641	297	67	2020	2020	NUM
bionys-641	297	68	;	;	PUNCT
bionys-641	297	69	thiruppathi	thiruppathi	PROPN
bionys-641	297	70	et	et	PROPN
bionys-641	297	71	al	al	PROPN
bionys-641	297	72	.	.	PROPN
bionys-641	297	73	,	,	PUNCT
bionys-641	297	74	2024	2024	NUM
bionys-641	297	75	)	)	PUNCT
bionys-641	297	76	.	.	PUNCT
bionys-641	298	1	this	this	DET
bionys-641	298	2	mechanism	mechanism	NOUN
bionys-641	298	3	initiates	initiate	VERB
bionys-641	298	4	a	a	DET
bionys-641	298	5	tumor	tumor	NOUN
bionys-641	298	6	-	-	PUNCT
bionys-641	298	7	specific	specific	ADJ
bionys-641	298	8	immune	immune	ADJ
bionys-641	298	9	cycle	cycle	NOUN
bionys-641	298	10	.	.	PUNCT
bionys-641	299	1	synergistic	synergistic	ADJ
bionys-641	299	2	strategies	strategy	NOUN
bionys-641	299	3	have	have	AUX
bionys-641	299	4	shown	show	VERB
bionys-641	299	5	improved	improved	ADJ
bionys-641	299	6	tumor	tumor	NOUN
bionys-641	299	7	control	control	NOUN
bionys-641	299	8	and	and	CCONJ
bionys-641	299	9	survival	survival	NOUN
bionys-641	299	10	compared	compare	VERB
bionys-641	299	11	to	to	ADP
bionys-641	299	12	singular	singular	ADJ
bionys-641	299	13	modalities	modality	NOUN
bionys-641	299	14	.	.	PUNCT
bionys-641	300	1	the	the	DET
bionys-641	300	2	interaction	interaction	NOUN
bionys-641	300	3	between	between	ADP
bionys-641	300	4	cell	cell	NOUN
bionys-641	300	5	death	death	NOUN
bionys-641	300	6	modulators	modulator	NOUN
bionys-641	300	7	and	and	CCONJ
bionys-641	300	8	immune	immune	ADJ
bionys-641	300	9	checkpoint	checkpoint	NOUN
bionys-641	300	10	blockade	blockade	NOUN
bionys-641	300	11	(	(	PUNCT
bionys-641	300	12	icb	icb	NOUN
bionys-641	300	13	)	)	PUNCT
bionys-641	300	14	transcends	transcend	VERB
bionys-641	300	15	drugs	drug	NOUN
bionys-641	300	16	that	that	PRON
bionys-641	300	17	induce	induce	VERB
bionys-641	300	18	traditional	traditional	ADJ
bionys-641	300	19	icd	icd	NOUN
bionys-641	300	20	within	within	ADP
bionys-641	300	21	the	the	DET
bionys-641	300	22	tumor	tumor	NOUN
bionys-641	300	23	cells	cell	NOUN
bionys-641	300	24	themselves	themselves	PRON
bionys-641	300	25	(	(	PUNCT
bionys-641	300	26	arimoto	arimoto	NOUN
bionys-641	300	27	et	et	PROPN
bionys-641	300	28	al	al	PROPN
bionys-641	300	29	.	.	PROPN
bionys-641	300	30	,	,	PUNCT
bionys-641	300	31	2024	2024	NUM
bionys-641	300	32	)	)	PUNCT
bionys-641	300	33	.	.	PUNCT
bionys-641	301	1	research	research	NOUN
bionys-641	301	2	on	on	ADP
bionys-641	301	3	the	the	DET
bionys-641	301	4	bcl-2	bcl-2	PUNCT
bionys-641	301	5	inhibitor	inhibitor	NOUN
bionys-641	301	6	venetoclax	venetoclax	NOUN
bionys-641	301	7	in	in	ADP
bionys-641	301	8	solid	solid	ADJ
bionys-641	301	9	tumor	tumor	NOUN
bionys-641	301	10	models	model	NOUN
bionys-641	301	11	has	have	AUX
bionys-641	301	12	revealed	reveal	VERB
bionys-641	301	13	a	a	DET
bionys-641	301	14	significant	significant	ADJ
bionys-641	301	15	alternative	alternative	ADJ
bionys-641	301	16	mechanism	mechanism	NOUN
bionys-641	301	17	.	.	PUNCT
bionys-641	302	1	venetoclax	venetoclax	NOUN
bionys-641	302	2	,	,	PUNCT
bionys-641	302	3	a	a	DET
bionys-641	302	4	selective	selective	ADJ
bionys-641	302	5	bcl-2	bcl-2	ADJ
bionys-641	302	6	inhibitor	inhibitor	NOUN
bionys-641	302	7	,	,	PUNCT
bionys-641	302	8	eliminates	eliminate	VERB
bionys-641	302	9	naive	naive	ADJ
bionys-641	302	10	and	and	CCONJ
bionys-641	302	11	memory	memory	NOUN
bionys-641	302	12	t	t	NOUN
bionys-641	302	13	cells	cell	NOUN
bionys-641	302	14	reliant	reliant	ADJ
bionys-641	302	15	on	on	ADP
bionys-641	302	16	bcl-2	bcl-2	NOUN
bionys-641	302	17	,	,	PUNCT
bionys-641	302	18	while	while	SCONJ
bionys-641	302	19	sparing	spare	VERB
bionys-641	302	20	effector	effector	NOUN
bionys-641	302	21	t	t	NOUN
bionys-641	302	22	cells	cell	NOUN
bionys-641	302	23	that	that	PRON
bionys-641	302	24	depend	depend	VERB
bionys-641	302	25	on	on	ADP
bionys-641	302	26	bcl	bcl	PROPN
bionys-641	302	27	-	-	PROPN
bionys-641	302	28	xl	xl	PROPN
bionys-641	302	29	and	and	CCONJ
bionys-641	302	30	exhibit	exhibit	VERB
bionys-641	302	31	resistance	resistance	NOUN
bionys-641	302	32	to	to	PART
bionys-641	302	33	venetoclax	venetoclax	VERB
bionys-641	302	34	.	.	PUNCT
bionys-641	303	1	this	this	DET
bionys-641	303	2	mechanism	mechanism	NOUN
bionys-641	303	3	induces	induce	VERB
bionys-641	303	4	an	an	DET
bionys-641	303	5	„	„	PUNCT
bionys-641	303	6	immune	immune	NOUN
bionys-641	303	7	-	-	PUNCT
bionys-641	303	8	sculpting	sculpting	NOUN
bionys-641	303	9	”	"	PUNCT
bionys-641	303	10	impact	impact	NOUN
bionys-641	303	11	in	in	ADP
bionys-641	303	12	the	the	DET
bionys-641	303	13	tme	tme	NOUN
bionys-641	303	14	,	,	PUNCT
bionys-641	303	15	which	which	PRON
bionys-641	303	16	selectively	selectively	ADV
bionys-641	303	17	eliminates	eliminate	VERB
bionys-641	303	18	less	less	ADV
bionys-641	303	19	active	active	ADJ
bionys-641	303	20	t	t	NOUN
bionys-641	303	21	-	-	PUNCT
bionys-641	303	22	cell	cell	NOUN
bionys-641	303	23	subsets	subset	NOUN
bionys-641	303	24	,	,	PUNCT
bionys-641	303	25	hence	hence	ADV
bionys-641	303	26	enhancing	enhance	VERB
bionys-641	303	27	conditions	condition	NOUN
bionys-641	303	28	for	for	ADP
bionys-641	303	29	pd1	pd1	NOUN
bionys-641	303	30	-	-	PUNCT
bionys-641	303	31	expressing	express	VERB
bionys-641	303	32	effector	effector	NOUN
bionys-641	303	33	t	t	NOUN
bionys-641	303	34	cells	cell	NOUN
bionys-641	303	35	,	,	PUNCT
bionys-641	303	36	the	the	DET
bionys-641	303	37	primary	primary	ADJ
bionys-641	303	38	target	target	NOUN
bionys-641	303	39	of	of	ADP
bionys-641	303	40	immune	immune	ADJ
bionys-641	303	41	checkpoint	checkpoint	NOUN
bionys-641	303	42	blockade	blockade	NOUN
bionys-641	303	43	(	(	PUNCT
bionys-641	303	44	icb	icb	PROPN
bionys-641	303	45	)	)	PUNCT
bionys-641	303	46	(	(	PUNCT
bionys-641	303	47	ludwig	ludwig	PROPN
bionys-641	303	48	et	et	PROPN
bionys-641	303	49	al	al	PROPN
bionys-641	303	50	.	.	PROPN
bionys-641	303	51	,	,	PUNCT
bionys-641	303	52	2021	2021	NUM
bionys-641	303	53	;	;	PUNCT
bionys-641	303	54	nagasaki	nagasaki	PROPN
bionys-641	303	55	et	et	PROPN
bionys-641	303	56	al	al	PROPN
bionys-641	303	57	.	.	PROPN
bionys-641	303	58	,	,	PUNCT
bionys-641	303	59	2024	2024	NUM
bionys-641	303	60	)	)	PUNCT
bionys-641	303	61	.	.	PUNCT
bionys-641	304	1	a	a	DET
bionys-641	304	2	major	major	ADJ
bionys-641	304	3	challenge	challenge	NOUN
bionys-641	304	4	in	in	ADP
bionys-641	304	5	the	the	DET
bionys-641	304	6	clinical	clinical	ADJ
bionys-641	304	7	application	application	NOUN
bionys-641	304	8	of	of	ADP
bionys-641	304	9	icd	icd	PROPN
bionys-641	304	10	-	-	PUNCT
bionys-641	304	11	based	base	VERB
bionys-641	304	12	combination	combination	NOUN
bionys-641	304	13	medicines	medicine	NOUN
bionys-641	304	14	is	be	AUX
bionys-641	304	15	the	the	DET
bionys-641	304	16	selection	selection	NOUN
bionys-641	304	17	of	of	ADP
bionys-641	304	18	individuals	individual	NOUN
bionys-641	304	19	who	who	PRON
bionys-641	304	20	are	be	AUX
bionys-641	304	21	most	most	ADV
bionys-641	304	22	likely	likely	ADJ
bionys-641	304	23	to	to	PART
bionys-641	304	24	benefit	benefit	VERB
bionys-641	304	25	.	.	PUNCT
bionys-641	305	1	this	this	PRON
bionys-641	305	2	has	have	AUX
bionys-641	305	3	prompted	prompt	VERB
bionys-641	305	4	the	the	DET
bionys-641	305	5	quest	quest	NOUN
bionys-641	305	6	for	for	ADP
bionys-641	305	7	reliable	reliable	ADJ
bionys-641	305	8	biomarkers	biomarker	NOUN
bionys-641	305	9	capable	capable	ADJ
bionys-641	305	10	of	of	ADP
bionys-641	305	11	predicting	predict	VERB
bionys-641	305	12	or	or	CCONJ
bionys-641	305	13	monitoring	monitor	VERB
bionys-641	305	14	the	the	DET
bionys-641	305	15	onset	onset	NOUN
bionys-641	305	16	of	of	ADP
bionys-641	305	17	an	an	DET
bionys-641	305	18	immunogenic	immunogenic	ADJ
bionys-641	305	19	response	response	NOUN
bionys-641	305	20	in	in	ADP
bionys-641	305	21	patients	patient	NOUN
bionys-641	305	22	.	.	PUNCT
bionys-641	306	1	potential	potential	ADJ
bionys-641	306	2	biomarkers	biomarker	NOUN
bionys-641	306	3	can	can	AUX
bionys-641	306	4	be	be	AUX
bionys-641	306	5	broadly	broadly	ADV
bionys-641	306	6	categorized	categorize	VERB
bionys-641	306	7	into	into	ADP
bionys-641	306	8	two	two	NUM
bionys-641	306	9	types	type	NOUN
bionys-641	306	10	:	:	PUNCT
bionys-641	306	11	those	those	PRON
bionys-641	306	12	that	that	PRON
bionys-641	306	13	quantify	quantify	VERB
bionys-641	306	14	the	the	DET
bionys-641	306	15	damps	damp	NOUN
bionys-641	306	16	directly	directly	ADV
bionys-641	306	17	and	and	CCONJ
bionys-641	306	18	those	those	PRON
bionys-641	306	19	that	that	PRON
bionys-641	306	20	assess	assess	VERB
bionys-641	306	21	the	the	DET
bionys-641	306	22	ensuing	ensue	VERB
bionys-641	306	23	immune	immune	ADJ
bionys-641	306	24	responses	response	NOUN
bionys-641	306	25	(	(	PUNCT
bionys-641	306	26	jiang	jiang	PROPN
bionys-641	306	27	et	et	PROPN
bionys-641	306	28	al	al	PROPN
bionys-641	306	29	.	.	PROPN
bionys-641	306	30	,	,	PUNCT
bionys-641	306	31	2021	2021	NUM
bionys-641	306	32	)	)	PUNCT
bionys-641	306	33	.	.	PUNCT
bionys-641	307	1	nonetheless	nonetheless	ADV
bionys-641	307	2	,	,	PUNCT
bionys-641	307	3	the	the	DET
bionys-641	307	4	results	result	NOUN
bionys-641	307	5	have	have	AUX
bionys-641	307	6	been	be	AUX
bionys-641	307	7	inconsistent	inconsistent	ADJ
bionys-641	307	8	across	across	ADP
bionys-641	307	9	different	different	ADJ
bionys-641	307	10	cancer	cancer	NOUN
bionys-641	307	11	types	type	NOUN
bionys-641	307	12	and	and	CCONJ
bionys-641	307	13	treatment	treatment	NOUN
bionys-641	307	14	modalities	modality	NOUN
bionys-641	307	15	due	due	ADJ
bionys-641	307	16	to	to	ADP
bionys-641	307	17	multiple	multiple	ADJ
bionys-641	307	18	challenges	challenge	NOUN
bionys-641	307	19	,	,	PUNCT
bionys-641	307	20	including	include	VERB
bionys-641	307	21	the	the	DET
bionys-641	307	22	technical	technical	ADJ
bionys-641	307	23	difficulties	difficulty	NOUN
bionys-641	307	24	in	in	ADP
bionys-641	307	25	standardizing	standardize	VERB
bionys-641	307	26	assays	assay	NOUN
bionys-641	307	27	,	,	PUNCT
bionys-641	307	28	the	the	DET
bionys-641	307	29	short	short	ADJ
bionys-641	307	30	half	half	ADJ
bionys-641	307	31	-	-	PUNCT
bionys-641	307	32	life	life	NOUN
bionys-641	307	33	of	of	ADP
bionys-641	307	34	these	these	DET
bionys-641	307	35	markers	marker	NOUN
bionys-641	307	36	,	,	PUNCT
bionys-641	307	37	and	and	CCONJ
bionys-641	307	38	the	the	DET
bionys-641	307	39	release	release	NOUN
bionys-641	307	40	of	of	ADP
bionys-641	307	41	damps	damp	NOUN
bionys-641	307	42	like	like	ADP
bionys-641	307	43	hmgb1	hmgb1	NOUN
bionys-641	307	44	during	during	ADP
bionys-641	307	45	non	non	ADJ
bionys-641	307	46	-	-	ADJ
bionys-641	307	47	icd	icd	ADJ
bionys-641	307	48	death	death	NOUN
bionys-641	307	49	or	or	CCONJ
bionys-641	307	50	sterile	sterile	ADJ
bionys-641	307	51	inflammation	inflammation	NOUN
bionys-641	307	52	,	,	PUNCT
bionys-641	307	53	which	which	PRON
bionys-641	307	54	limits	limit	VERB
bionys-641	307	55	their	their	PRON
bionys-641	307	56	specificity	specificity	NOUN
bionys-641	307	57	as	as	ADP
bionys-641	307	58	icd	icd	PROPN
bionys-641	307	59	biomarkers	biomarker	NOUN
bionys-641	307	60	(	(	PUNCT
bionys-641	307	61	ahmed	ahmed	PROPN
bionys-641	307	62	&	&	CCONJ
bionys-641	307	63	tait	tait	PROPN
bionys-641	307	64	,	,	PUNCT
bionys-641	307	65	2020	2020	NUM
bionys-641	307	66	;	;	PUNCT
bionys-641	307	67	thiruppathi	thiruppathi	PROPN
bionys-641	307	68	et	et	PROPN
bionys-641	307	69	al	al	PROPN
bionys-641	307	70	.	.	PROPN
bionys-641	307	71	,	,	PUNCT
bionys-641	307	72	2024	2024	NUM
bionys-641	307	73	)	)	PUNCT
bionys-641	307	74	.	.	PUNCT
bionys-641	308	1	conclusion	conclusion	NOUN
bionys-641	308	2	cell	cell	NOUN
bionys-641	308	3	death	death	NOUN
bionys-641	308	4	is	be	AUX
bionys-641	308	5	a	a	DET
bionys-641	308	6	natural	natural	ADJ
bionys-641	308	7	process	process	NOUN
bionys-641	308	8	that	that	PRON
bionys-641	308	9	maintains	maintain	VERB
bionys-641	308	10	bodily	bodily	ADJ
bionys-641	308	11	homeostasis	homeostasis	NOUN
bionys-641	308	12	.	.	PUNCT
bionys-641	309	1	the	the	DET
bionys-641	309	2	body	body	NOUN
bionys-641	309	3	's	's	PART
bionys-641	309	4	primary	primary	ADJ
bionys-641	309	5	strategy	strategy	NOUN
bionys-641	309	6	for	for	ADP
bionys-641	309	7	maintaining	maintain	VERB
bionys-641	309	8	homeostasis	homeostasis	NOUN
bionys-641	309	9	is	be	AUX
bionys-641	309	10	the	the	DET
bionys-641	309	11	selective	selective	ADJ
bionys-641	309	12	elimination	elimination	NOUN
bionys-641	309	13	of	of	ADP
bionys-641	309	14	dangerous	dangerous	ADJ
bionys-641	309	15	or	or	CCONJ
bionys-641	309	16	contaminated	contaminated	ADJ
bionys-641	309	17	cells	cell	NOUN
bionys-641	309	18	.	.	PUNCT
bionys-641	310	1	this	this	DET
bionys-641	310	2	process	process	NOUN
bionys-641	310	3	may	may	AUX
bionys-641	310	4	occur	occur	VERB
bionys-641	310	5	through	through	ADP
bionys-641	310	6	various	various	ADJ
bionys-641	310	7	processes	process	NOUN
bionys-641	310	8	,	,	PUNCT
bionys-641	310	9	resulting	result	VERB
bionys-641	310	10	in	in	ADP
bionys-641	310	11	distinct	distinct	ADJ
bionys-641	310	12	morphological	morphological	ADJ
bionys-641	310	13	alterations	alteration	NOUN
bionys-641	310	14	and	and	CCONJ
bionys-641	310	15	immunological	immunological	ADJ
bionys-641	310	16	responses	response	NOUN
bionys-641	310	17	,	,	PUNCT
bionys-641	310	18	broadly	broadly	ADV
bionys-641	310	19	defined	define	VERB
bionys-641	310	20	as	as	ADP
bionys-641	310	21	controlled	control	VERB
bionys-641	310	22	and	and	CCONJ
bionys-641	310	23	uncontrolled	uncontrolled	ADJ
bionys-641	310	24	cell	cell	NOUN
bionys-641	310	25	death	death	NOUN
bionys-641	310	26	.	.	PUNCT
bionys-641	311	1	oxidative	oxidative	ADJ
bionys-641	311	2	stress	stress	NOUN
bionys-641	311	3	is	be	AUX
bionys-641	311	4	a	a	DET
bionys-641	311	5	common	common	ADJ
bionys-641	311	6	cause	cause	NOUN
bionys-641	311	7	of	of	ADP
bionys-641	311	8	cell	cell	NOUN
bionys-641	311	9	death	death	NOUN
bionys-641	311	10	.	.	PUNCT
bionys-641	312	1	a	a	DET
bionys-641	312	2	greater	great	ADJ
bionys-641	312	3	understanding	understanding	NOUN
bionys-641	312	4	of	of	ADP
bionys-641	312	5	the	the	DET
bionys-641	312	6	biologica	biologica	PROPN
bionys-641	312	7	nyssana	nyssana	PROPN
bionys-641	313	1	●	●	PUNCT
bionys-641	313	2	16	16	NUM
bionys-641	313	3	(	(	PUNCT
bionys-641	313	4	2	2	NUM
bionys-641	313	5	)	)	PUNCT
bionys-641	313	6	december	december	PROPN
bionys-641	313	7	2025	2025	NUM
bionys-641	313	8	:	:	PUNCT
bionys-641	313	9	liana	liana	NOUN
bionys-641	313	10	et	et	PROPN
bionys-641	313	11	al	al	PROPN
bionys-641	313	12	.	.	PUNCT
bionys-641	314	1	●	●	PUNCT
bionys-641	314	2	cell	cell	NOUN
bionys-641	314	3	deaths	death	NOUN
bionys-641	314	4	and	and	CCONJ
bionys-641	314	5	their	their	PRON
bionys-641	314	6	associated	associate	VERB
bionys-641	314	7	mechanisms	mechanism	NOUN
bionys-641	314	8	fig	fig	NOUN
bionys-641	314	9	.	.	PUNCT
bionys-641	315	1	3	3	X
bionys-641	315	2	.	.	X
bionys-641	315	3	therapeutic	therapeutic	ADJ
bionys-641	315	4	implications	implication	NOUN
bionys-641	315	5	of	of	ADP
bionys-641	315	6	cell	cell	NOUN
bionys-641	315	7	death	death	NOUN
bionys-641	315	8	regulation	regulation	NOUN
bionys-641	315	9	many	many	ADJ
bionys-641	315	10	types	type	NOUN
bionys-641	315	11	of	of	ADP
bionys-641	315	12	cell	cell	NOUN
bionys-641	315	13	death	death	NOUN
bionys-641	315	14	can	can	AUX
bionys-641	315	15	help	help	VERB
bionys-641	315	16	design	design	VERB
bionys-641	315	17	better	well	ADJ
bionys-641	315	18	and	and	CCONJ
bionys-641	315	19	more	more	ADV
bionys-641	315	20	effective	effective	ADJ
bionys-641	315	21	treatments	treatment	NOUN
bionys-641	315	22	for	for	ADP
bionys-641	315	23	diseases	disease	NOUN
bionys-641	315	24	like	like	ADP
bionys-641	315	25	cancer	cancer	NOUN
bionys-641	315	26	.	.	PUNCT
bionys-641	316	1	references	reference	NOUN
bionys-641	316	2	abastado	abastado	VERB
bionys-641	316	3	,	,	PUNCT
bionys-641	316	4	j.-p	j.-p	PROPN
bionys-641	316	5	.	.	PUNCT
bionys-641	317	1	(	(	PUNCT
bionys-641	317	2	2015	2015	NUM
bionys-641	317	3	)	)	PUNCT
bionys-641	317	4	.	.	PUNCT
bionys-641	318	1	cancer	cancer	NOUN
bionys-641	318	2	cells	cell	NOUN
bionys-641	318	3	are	be	AUX
bionys-641	318	4	addicted	addict	VERB
bionys-641	318	5	to	to	ADP
bionys-641	318	6	inhibitors	inhibitor	NOUN
bionys-641	318	7	of	of	ADP
bionys-641	318	8	apoptosis	apoptosis	NOUN
bionys-641	318	9	.	.	PUNCT
bionys-641	319	1	annals	annal	NOUN
bionys-641	319	2	of	of	ADP
bionys-641	319	3	oncology	oncology	NOUN
bionys-641	319	4	,	,	PUNCT
bionys-641	319	5	26	26	NUM
bionys-641	319	6	,	,	PUNCT
bionys-641	319	7	ii6	ii6	NOUN
bionys-641	319	8	.	.	PUNCT
bionys-641	320	1	https://doi.org/10.1093/annonc/mdv082.5	https://doi.org/10.1093/annonc/mdv082.5	PROPN
bionys-641	320	2	abreu	abreu	PROPN
bionys-641	320	3	velez	velez	PROPN
bionys-641	320	4	,	,	PUNCT
bionys-641	320	5	a.m.	a.m.	ADV
bionys-641	320	6	,	,	PUNCT
bionys-641	320	7	&	&	CCONJ
bionys-641	320	8	howard	howard	PROPN
bionys-641	320	9	,	,	PUNCT
bionys-641	320	10	m.s	m.s	PROPN
bionys-641	320	11	.	.	PROPN
bionys-641	320	12	(	(	PUNCT
bionys-641	320	13	2015	2015	NUM
bionys-641	320	14	)	)	PUNCT
bionys-641	320	15	.	.	PUNCT
bionys-641	321	1	tumor	tumor	NOUN
bionys-641	321	2	-	-	PUNCT
bionys-641	321	3	suppressor	suppressor	NOUN
bionys-641	321	4	genes	gene	NOUN
bionys-641	321	5	,	,	PUNCT
bionys-641	321	6	cell	cell	NOUN
bionys-641	321	7	cycle	cycle	NOUN
bionys-641	321	8	regulatory	regulatory	ADJ
bionys-641	321	9	checkpoints	checkpoint	NOUN
bionys-641	321	10	,	,	PUNCT
bionys-641	321	11	and	and	CCONJ
bionys-641	321	12	the	the	DET
bionys-641	321	13	skin	skin	NOUN
bionys-641	321	14	.	.	PUNCT
bionys-641	322	1	north	north	NOUN
bionys-641	322	2	american	american	PROPN
bionys-641	322	3	journal	journal	PROPN
bionys-641	322	4	of	of	ADP
bionys-641	322	5	medical	medical	ADJ
bionys-641	322	6	sciences	science	NOUN
bionys-641	322	7	,	,	PUNCT
bionys-641	322	8	7(5	7(5	NUM
bionys-641	322	9	)	)	PUNCT
bionys-641	322	10	,	,	PUNCT
bionys-641	322	11	176–188	176–188	NUM
bionys-641	322	12	.	.	PUNCT
bionys-641	323	1	https://doi	https://doi	PROPN
bionys-641	323	2	.	.	PUNCT
bionys-641	323	3	org/10.4103/1947	org/10.4103/1947	PROPN
bionys-641	323	4	-	-	PUNCT
bionys-641	323	5	2714.157476	2714.157476	NOUN
bionys-641	323	6	ahmed	ahme	VERB
bionys-641	323	7	,	,	PUNCT
bionys-641	323	8	a.	a.	PROPN
bionys-641	323	9	&	&	CCONJ
bionys-641	323	10	tait	tait	PROPN
bionys-641	323	11	,	,	PUNCT
bionys-641	323	12	s.w.g	s.w.g	NOUN
bionys-641	323	13	.	.	PUNCT
bionys-641	323	14	(	(	PUNCT
bionys-641	323	15	2020	2020	NUM
bionys-641	323	16	)	)	PUNCT
bionys-641	323	17	.	.	PUNCT
bionys-641	324	1	targeting	target	VERB
bionys-641	324	2	immunogenic	immunogenic	ADJ
bionys-641	324	3	cell	cell	NOUN
bionys-641	324	4	death	death	NOUN
bionys-641	324	5	in	in	ADP
bionys-641	324	6	cancer	cancer	NOUN
bionys-641	324	7	.	.	PUNCT
bionys-641	325	1	molecular	molecular	ADJ
bionys-641	325	2	oncology	oncology	NOUN
bionys-641	325	3	,	,	PUNCT
bionys-641	325	4	14(12	14(12	NUM
bionys-641	325	5	)	)	PUNCT
bionys-641	325	6	,	,	PUNCT
bionys-641	325	7	2994–3006	2994–3006	NUM
bionys-641	325	8	.	.	PUNCT
bionys-641	326	1	https://doi	https://doi	NOUN
bionys-641	326	2	.	.	PUNCT
bionys-641	326	3	org/10.1002/1878	org/10.1002/1878	PROPN
bionys-641	326	4	-	-	PUNCT
bionys-641	326	5	0261.12851	0261.12851	NOUN
bionys-641	326	6	alvarado	alvarado	PROPN
bionys-641	326	7	,	,	PUNCT
bionys-641	326	8	c.	c.	PROPN
bionys-641	326	9	,	,	PUNCT
bionys-641	326	10	fider	fider	NOUN
bionys-641	326	11	,	,	PUNCT
bionys-641	326	12	n.a	n.a	PROPN
bionys-641	326	13	.	.	PROPN
bionys-641	326	14	,	,	PUNCT
bionys-641	326	15	wearing	wear	VERB
bionys-641	326	16	,	,	PUNCT
bionys-641	326	17	h.j	h.j	PROPN
bionys-641	326	18	.	.	PROPN
bionys-641	326	19	,	,	PUNCT
bionys-641	326	20	&	&	CCONJ
bionys-641	326	21	komarova	komarova	PROPN
bionys-641	326	22	,	,	PUNCT
bionys-641	326	23	n.l	n.l	PROPN
bionys-641	326	24	.	.	PROPN
bionys-641	326	25	(	(	PUNCT
bionys-641	326	26	2018	2018	NUM
bionys-641	326	27	)	)	PUNCT
bionys-641	326	28	.	.	PUNCT
bionys-641	327	1	optimizing	optimize	VERB
bionys-641	327	2	homeostatic	homeostatic	ADJ
bionys-641	327	3	cell	cell	NOUN
bionys-641	327	4	renewal	renewal	NOUN
bionys-641	327	5	in	in	ADP
bionys-641	327	6	hierarchical	hierarchical	ADJ
bionys-641	327	7	tissues	tissue	NOUN
bionys-641	327	8	.	.	PUNCT
bionys-641	328	1	plos	plos	PROPN
bionys-641	328	2	computational	computational	ADJ
bionys-641	328	3	biology	biology	NOUN
bionys-641	328	4	,	,	PUNCT
bionys-641	328	5	14(2	14(2	NUM
bionys-641	328	6	)	)	PUNCT
bionys-641	328	7	,	,	PUNCT
bionys-641	328	8	e1005967	e1005967	PROPN
bionys-641	328	9	.	.	PUNCT
bionys-641	329	1	https://	https://	PROPN
bionys-641	329	2	doi.org/10.1371/journal.pcbi.1005967	doi.org/10.1371/journal.pcbi.1005967	PROPN
bionys-641	329	3	andrabi	andrabi	NOUN
bionys-641	329	4	,	,	PUNCT
bionys-641	329	5	s.a	s.a	PROPN
bionys-641	329	6	.	.	PROPN
bionys-641	329	7	,	,	PUNCT
bionys-641	329	8	dawson	dawson	PROPN
bionys-641	329	9	,	,	PUNCT
bionys-641	329	10	t.m	t.m	PROPN
bionys-641	329	11	.	.	PROPN
bionys-641	329	12	,	,	PUNCT
bionys-641	329	13	&	&	CCONJ
bionys-641	329	14	dawson	dawson	PROPN
bionys-641	329	15	,	,	PUNCT
bionys-641	329	16	v.l	v.l	PROPN
bionys-641	329	17	.	.	PROPN
bionys-641	329	18	(	(	PUNCT
bionys-641	329	19	2008	2008	NUM
bionys-641	329	20	)	)	PUNCT
bionys-641	329	21	.	.	PUNCT
bionys-641	330	1	mitochondrial	mitochondrial	ADJ
bionys-641	330	2	and	and	CCONJ
bionys-641	330	3	nuclear	nuclear	ADJ
bionys-641	330	4	cross	cross	NOUN
bionys-641	330	5	talk	talk	NOUN
bionys-641	330	6	in	in	ADP
bionys-641	330	7	cell	cell	NOUN
bionys-641	330	8	death	death	NOUN
bionys-641	330	9	:	:	PUNCT
bionys-641	331	1	parthanatos	parthanato	NOUN
bionys-641	331	2	.	.	PUNCT
bionys-641	332	1	annals	annal	NOUN
bionys-641	332	2	of	of	ADP
bionys-641	332	3	the	the	DET
bionys-641	332	4	new	new	PROPN
bionys-641	332	5	york	york	PROPN
bionys-641	332	6	academy	academy	PROPN
bionys-641	332	7	of	of	ADP
bionys-641	332	8	sciences	sciences	PROPN
bionys-641	332	9	,	,	PUNCT
bionys-641	332	10	1147	1147	NUM
bionys-641	332	11	,	,	PUNCT
bionys-641	332	12	233–241	233–241	NUM
bionys-641	332	13	.	.	PUNCT
bionys-641	333	1	https://doi.org/10.1196/	https://doi.org/10.1196/	PROPN
bionys-641	333	2	annals.1427.014	annals.1427.014	PROPN
bionys-641	333	3	aral	aral	PROPN
bionys-641	333	4	,	,	PUNCT
bionys-641	333	5	k.	k.	PROPN
bionys-641	333	6	,	,	PUNCT
bionys-641	333	7	aral	aral	PROPN
bionys-641	333	8	,	,	PUNCT
bionys-641	333	9	c.a	c.a	PROPN
bionys-641	333	10	.	.	PROPN
bionys-641	333	11	,	,	PUNCT
bionys-641	333	12	&	&	CCONJ
bionys-641	333	13	kapila	kapila	PROPN
bionys-641	333	14	,	,	PUNCT
bionys-641	333	15	y.	y.	PROPN
bionys-641	333	16	(	(	PUNCT
bionys-641	333	17	2019	2019	NUM
bionys-641	333	18	)	)	PUNCT
bionys-641	333	19	.	.	PUNCT
bionys-641	334	1	the	the	DET
bionys-641	334	2	role	role	NOUN
bionys-641	334	3	of	of	ADP
bionys-641	334	4	caspase-8	caspase-8	PROPN
bionys-641	334	5	,	,	PUNCT
bionys-641	334	6	caspase-9	caspase-9	PROPN
bionys-641	334	7	,	,	PUNCT
bionys-641	334	8	and	and	CCONJ
bionys-641	334	9	apoptosis	apoptosis	NOUN
bionys-641	334	10	inducing	induce	VERB
bionys-641	334	11	factor	factor	NOUN
bionys-641	334	12	in	in	ADP
bionys-641	334	13	periodontal	periodontal	ADJ
bionys-641	334	14	disease	disease	NOUN
bionys-641	334	15	.	.	PUNCT
bionys-641	335	1	journal	journal	PROPN
bionys-641	335	2	of	of	ADP
bionys-641	335	3	periodontology	periodontology	NOUN
bionys-641	335	4	,	,	PUNCT
bionys-641	335	5	90(3	90(3	NOUN
bionys-641	335	6	)	)	PUNCT
bionys-641	335	7	,	,	PUNCT
bionys-641	335	8	288–294	288–294	NUM
bionys-641	335	9	.	.	PUNCT
bionys-641	336	1	https://doi.org/10.1002/jper.170716	https://doi.org/10.1002/jper.170716	NOUN
bionys-641	336	2	arimoto	arimoto	NOUN
bionys-641	336	3	,	,	PUNCT
bionys-641	336	4	k.-i	k.-i	PROPN
bionys-641	336	5	.	.	PROPN
bionys-641	336	6	,	,	PUNCT
bionys-641	336	7	miyauchi	miyauchi	PROPN
bionys-641	336	8	,	,	PUNCT
bionys-641	336	9	s.	s.	PROPN
bionys-641	336	10	,	,	PUNCT
bionys-641	336	11	liu	liu	PROPN
bionys-641	336	12	,	,	PUNCT
bionys-641	336	13	m.	m.	NOUN
bionys-641	336	14	,	,	PUNCT
bionys-641	336	15	&	&	CCONJ
bionys-641	336	16	zhang	zhang	PROPN
bionys-641	336	17	,	,	PUNCT
bionys-641	336	18	d.-e	d.-e	PROPN
bionys-641	336	19	.	.	PUNCT
bionys-641	337	1	(	(	PUNCT
bionys-641	337	2	2024	2024	NUM
bionys-641	337	3	)	)	PUNCT
bionys-641	337	4	.	.	PUNCT
bionys-641	338	1	emerging	emerge	VERB
bionys-641	338	2	role	role	NOUN
bionys-641	338	3	of	of	ADP
bionys-641	338	4	immunogenic	immunogenic	ADJ
bionys-641	338	5	cell	cell	NOUN
bionys-641	338	6	death	death	NOUN
bionys-641	338	7	in	in	ADP
bionys-641	338	8	cancer	cancer	NOUN
bionys-641	338	9	immunotherapy	immunotherapy	NOUN
bionys-641	338	10	.	.	PUNCT
bionys-641	339	1	frontiers	frontier	NOUN
bionys-641	339	2	in	in	ADP
bionys-641	339	3	immunology	immunology	NOUN
bionys-641	339	4	,	,	PUNCT
bionys-641	339	5	15	15	NUM
bionys-641	339	6	,	,	PUNCT
bionys-641	339	7	1390263	1390263	NUM
bionys-641	339	8	.	.	PUNCT
bionys-641	340	1	https://doi.org/10.3389/	https://doi.org/10.3389/	NOUN
bionys-641	340	2	fimmu.2024.1390263	fimmu.2024.1390263	ADV
bionys-641	340	3	ballabio	ballabio	VERB
bionys-641	340	4	,	,	PUNCT
bionys-641	340	5	a.	a.	PROPN
bionys-641	340	6	&	&	CCONJ
bionys-641	340	7	bonifacino	bonifacino	PROPN
bionys-641	340	8	,	,	PUNCT
bionys-641	340	9	j.	j.	PROPN
bionys-641	340	10	(	(	PUNCT
bionys-641	340	11	2019	2019	NUM
bionys-641	340	12	)	)	PUNCT
bionys-641	340	13	.	.	PUNCT
bionys-641	341	1	lysosomes	lysosome	NOUN
bionys-641	341	2	as	as	ADP
bionys-641	341	3	dynamic	dynamic	ADJ
bionys-641	341	4	regulators	regulator	NOUN
bionys-641	341	5	of	of	ADP
bionys-641	341	6	cell	cell	NOUN
bionys-641	341	7	and	and	CCONJ
bionys-641	341	8	organismal	organismal	ADJ
bionys-641	341	9	homeostasis	homeostasis	NOUN
bionys-641	341	10	.	.	PUNCT
bionys-641	342	1	nature	nature	NOUN
bionys-641	342	2	reviews	review	VERB
bionys-641	342	3	molecular	molecular	ADJ
bionys-641	342	4	cell	cell	NOUN
bionys-641	342	5	biology	biology	NOUN
bionys-641	342	6	,	,	PUNCT
bionys-641	342	7	21	21	NUM
bionys-641	342	8	.	.	PUNCT
bionys-641	343	1	https://doi.org/10.1038/s41580-0190185-4	https://doi.org/10.1038/s41580-0190185-4	PROPN
bionys-641	343	2	bandyopadhyay	bandyopadhyay	NOUN
bionys-641	343	3	,	,	PUNCT
bionys-641	343	4	u.	u.	PROPN
bionys-641	343	5	,	,	PUNCT
bionys-641	343	6	kaushik	kaushik	PROPN
bionys-641	343	7	,	,	PUNCT
bionys-641	343	8	s.	s.	PROPN
bionys-641	343	9	,	,	PUNCT
bionys-641	343	10	varticovski	varticovski	PROPN
bionys-641	343	11	,	,	PUNCT
bionys-641	343	12	l.	l.	PROPN
bionys-641	343	13	,	,	PUNCT
bionys-641	343	14	&	&	CCONJ
bionys-641	343	15	cuervo	cuervo	PROPN
bionys-641	343	16	,	,	PUNCT
bionys-641	343	17	a.m.	a.m.	PROPN
bionys-641	343	18	(	(	PUNCT
bionys-641	343	19	2008	2008	NUM
bionys-641	343	20	)	)	PUNCT
bionys-641	343	21	.	.	PUNCT
bionys-641	344	1	the	the	DET
bionys-641	344	2	chaperone	chaperone	NOUN
bionys-641	344	3	-	-	PUNCT
bionys-641	344	4	mediated	mediate	VERB
bionys-641	344	5	autophagy	autophagy	NOUN
bionys-641	344	6	receptor	receptor	NOUN
bionys-641	344	7	organizes	organize	VERB
bionys-641	344	8	in	in	ADP
bionys-641	344	9	dynamic	dynamic	ADJ
bionys-641	344	10	protein	protein	NOUN
bionys-641	344	11	complexes	complex	NOUN
bionys-641	344	12	at	at	ADP
bionys-641	344	13	the	the	DET
bionys-641	344	14	lysosomal	lysosomal	ADJ
bionys-641	344	15	membrane	membrane	NOUN
bionys-641	344	16	.	.	PUNCT
bionys-641	345	1	molecular	molecular	ADJ
bionys-641	345	2	and	and	CCONJ
bionys-641	345	3	cellular	cellular	ADJ
bionys-641	345	4	biology	biology	NOUN
bionys-641	345	5	,	,	PUNCT
bionys-641	345	6	28(18	28(18	NUM
bionys-641	345	7	)	)	PUNCT
bionys-641	345	8	,	,	PUNCT
bionys-641	345	9	5747–5763	5747–5763	NUM
bionys-641	345	10	.	.	PUNCT
bionys-641	346	1	https://	https://	PROPN
bionys-641	346	2	doi.org/10.1128/mcb.02070-07	doi.org/10.1128/mcb.02070-07	PROPN
bionys-641	346	3	barmaki	barmaki	PROPN
bionys-641	346	4	,	,	PUNCT
bionys-641	346	5	h.	h.	PROPN
bionys-641	346	6	,	,	PUNCT
bionys-641	346	7	nourazarian	nourazarian	PROPN
bionys-641	346	8	,	,	PUNCT
bionys-641	346	9	a.	a.	PROPN
bionys-641	346	10	,	,	PUNCT
bionys-641	346	11	&	&	CCONJ
bionys-641	346	12	khaki	khaki	ADJ
bionys-641	346	13	-	-	PUNCT
bionys-641	346	14	khatibi	khatibi	NOUN
bionys-641	346	15	,	,	PUNCT
bionys-641	346	16	f.	f.	PROPN
bionys-641	346	17	(	(	PUNCT
bionys-641	346	18	2023	2023	NUM
bionys-641	346	19	)	)	PUNCT
bionys-641	346	20	.	.	PUNCT
bionys-641	347	1	proteostasis	proteostasis	NOUN
bionys-641	347	2	and	and	CCONJ
bionys-641	347	3	neurodegeneration	neurodegeneration	NOUN
bionys-641	347	4	:	:	PUNCT
bionys-641	347	5	a	a	DET
bionys-641	347	6	closer	close	ADJ
bionys-641	347	7	look	look	NOUN
bionys-641	347	8	at	at	ADP
bionys-641	347	9	autophagy	autophagy	NOUN
bionys-641	347	10	in	in	ADP
bionys-641	347	11	alzheimer	alzheimer	PROPN
bionys-641	347	12	’s	’s	PART
bionys-641	347	13	disease	disease	NOUN
bionys-641	347	14	.	.	PUNCT
bionys-641	348	1	frontiers	frontier	NOUN
bionys-641	348	2	in	in	ADP
bionys-641	348	3	aging	age	VERB
bionys-641	348	4	neuroscience	neuroscience	NOUN
bionys-641	348	5	,	,	PUNCT
bionys-641	348	6	15	15	NUM
bionys-641	348	7	,	,	PUNCT
bionys-641	348	8	1281338	1281338	NUM
bionys-641	348	9	.	.	PUNCT
bionys-641	349	1	https://doi.org/10.3389/fnagi.2023.1281338	https://doi.org/10.3389/fnagi.2023.1281338	PROPN
bionys-641	349	2	berghe	berghe	NOUN
bionys-641	349	3	,	,	PUNCT
bionys-641	349	4	t.v	t.v	PROPN
bionys-641	349	5	.	.	PROPN
bionys-641	349	6	,	,	PUNCT
bionys-641	349	7	linkermann	linkermann	PROPN
bionys-641	349	8	,	,	PUNCT
bionys-641	349	9	a.	a.	NOUN
bionys-641	349	10	,	,	PUNCT
bionys-641	349	11	jouan	jouan	PROPN
bionys-641	349	12	-	-	PUNCT
bionys-641	349	13	lanhouet	lanhouet	PROPN
bionys-641	349	14	,	,	PUNCT
bionys-641	349	15	s.	s.	PROPN
bionys-641	349	16	,	,	PUNCT
bionys-641	349	17	walczak	walczak	NOUN
bionys-641	349	18	,	,	PUNCT
bionys-641	349	19	h.	h.	PROPN
bionys-641	349	20	,	,	PUNCT
bionys-641	349	21	&	&	CCONJ
bionys-641	349	22	vandenabeele	vandenabeele	PROPN
bionys-641	349	23	,	,	PUNCT
bionys-641	349	24	p.	p.	NOUN
bionys-641	349	25	(	(	PUNCT
bionys-641	349	26	2014	2014	NUM
bionys-641	349	27	)	)	PUNCT
bionys-641	349	28	.	.	PUNCT
bionys-641	350	1	regulated	regulate	VERB
bionys-641	350	2	necrosis	necrosis	NOUN
bionys-641	350	3	:	:	PUNCT
bionys-641	350	4	the	the	DET
bionys-641	350	5	expanding	expand	VERB
bionys-641	350	6	network	network	NOUN
bionys-641	350	7	of	of	ADP
bionys-641	350	8	nonapoptotic	nonapoptotic	ADJ
bionys-641	350	9	cell	cell	NOUN
bionys-641	350	10	death	death	NOUN
bionys-641	350	11	pathways	pathway	NOUN
bionys-641	350	12	.	.	PUNCT
bionys-641	351	1	nature	nature	NOUN
bionys-641	351	2	reviews	review	VERB
bionys-641	351	3	molecular	molecular	ADJ
bionys-641	351	4	cell	cell	NOUN
bionys-641	351	5	biology	biology	NOUN
bionys-641	351	6	,	,	PUNCT
bionys-641	351	7	15(2	15(2	NUM
bionys-641	351	8	)	)	PUNCT
bionys-641	351	9	,	,	PUNCT
bionys-641	351	10	135–147	135–147	NUM
bionys-641	351	11	.	.	PUNCT
bionys-641	352	1	https://doi	https://doi	NOUN
bionys-641	352	2	.	.	PUNCT
bionys-641	352	3	org/10.1038	org/10.1038	PROPN
bionys-641	352	4	/	/	SYM
bionys-641	352	5	nrm3737	nrm3737	NOUN
bionys-641	352	6	berghe	berghe	NOUN
bionys-641	352	7	,	,	PUNCT
bionys-641	352	8	t.v	t.v	PROPN
bionys-641	352	9	.	.	PROPN
bionys-641	352	10	,	,	PUNCT
bionys-641	352	11	vanlangenakker	vanlangenakker	PROPN
bionys-641	352	12	,	,	PUNCT
bionys-641	352	13	n.	n.	NOUN
bionys-641	352	14	,	,	PUNCT
bionys-641	352	15	parthoens	parthoen	NOUN
bionys-641	352	16	,	,	PUNCT
bionys-641	352	17	e.	e.	PROPN
bionys-641	352	18	,	,	PUNCT
bionys-641	352	19	deckers	deckers	PROPN
bionys-641	352	20	,	,	PUNCT
bionys-641	352	21	w.	w.	PROPN
bionys-641	352	22	,	,	PUNCT
bionys-641	352	23	devos	devos	PROPN
bionys-641	352	24	,	,	PUNCT
bionys-641	352	25	m.	m.	NOUN
bionys-641	352	26	,	,	PUNCT
bionys-641	352	27	festjens	festjens	PROPN
bionys-641	352	28	,	,	PUNCT
bionys-641	352	29	n.	n.	NOUN
bionys-641	352	30	,	,	PUNCT
bionys-641	352	31	guerin	guerin	PROPN
bionys-641	352	32	,	,	PUNCT
bionys-641	352	33	c.j	c.j	PROPN
bionys-641	352	34	.	.	PROPN
bionys-641	352	35	,	,	PUNCT
bionys-641	352	36	brunk	brunk	PROPN
bionys-641	352	37	,	,	PUNCT
bionys-641	352	38	u.t	u.t	PROPN
bionys-641	352	39	.	.	PROPN
bionys-641	352	40	,	,	PUNCT
bionys-641	352	41	declercq	declercq	PROPN
bionys-641	352	42	,	,	PUNCT
bionys-641	352	43	w.	w.	PROPN
bionys-641	352	44	,	,	PUNCT
bionys-641	352	45	&	&	CCONJ
bionys-641	352	46	vandenabeele	vandenabeele	PROPN
bionys-641	352	47	,	,	PUNCT
bionys-641	352	48	p.	p.	NOUN
bionys-641	352	49	(	(	PUNCT
bionys-641	352	50	2010	2010	NUM
bionys-641	352	51	)	)	PUNCT
bionys-641	352	52	.	.	PUNCT
bionys-641	353	1	necroptosis	necroptosis	NOUN
bionys-641	353	2	,	,	PUNCT
bionys-641	353	3	necrosis	necrosis	NOUN
bionys-641	353	4	and	and	CCONJ
bionys-641	353	5	secondary	secondary	ADJ
bionys-641	353	6	necrosis	necrosis	NOUN
bionys-641	353	7	converge	converge	NOUN
bionys-641	353	8	on	on	ADP
bionys-641	353	9	similar	similar	ADJ
bionys-641	353	10	cellular	cellular	ADJ
bionys-641	353	11	disintegration	disintegration	NOUN
bionys-641	353	12	features	feature	NOUN
bionys-641	353	13	.	.	PUNCT
bionys-641	354	1	cell	cell	NOUN
bionys-641	354	2	death	death	NOUN
bionys-641	354	3	&	&	CCONJ
bionys-641	354	4	differentiation	differentiation	NOUN
bionys-641	354	5	,	,	PUNCT
bionys-641	354	6	17(6	17(6	NUM
bionys-641	354	7	)	)	PUNCT
bionys-641	354	8	,	,	PUNCT
bionys-641	354	9	922	922	NUM
bionys-641	354	10	–	–	PUNCT
bionys-641	354	11	930	930	NUM
bionys-641	354	12	.	.	PUNCT
bionys-641	355	1	https://doi.org/10.1038/cdd.2009.184	https://doi.org/10.1038/cdd.2009.184	NOUN
bionys-641	355	2	bittner	bittner	PROPN
bionys-641	355	3	,	,	PUNCT
bionys-641	355	4	s.	s.	PROPN
bionys-641	355	5	,	,	PUNCT
bionys-641	355	6	knoll	knoll	PROPN
bionys-641	355	7	,	,	PUNCT
bionys-641	355	8	g.	g.	PROPN
bionys-641	355	9	,	,	PUNCT
bionys-641	355	10	füllsack	füllsack	NOUN
bionys-641	355	11	,	,	PUNCT
bionys-641	355	12	s.	s.	PROPN
bionys-641	355	13	,	,	PUNCT
bionys-641	355	14	kurz	kurz	PROPN
bionys-641	355	15	,	,	PUNCT
bionys-641	355	16	m.	m.	NOUN
bionys-641	355	17	,	,	PUNCT
bionys-641	355	18	wajant	wajant	NOUN
bionys-641	355	19	,	,	PUNCT
bionys-641	355	20	h.	h.	PROPN
bionys-641	355	21	,	,	PUNCT
bionys-641	355	22	&	&	CCONJ
bionys-641	355	23	ehrenschwender	ehrenschwender	NOUN
bionys-641	355	24	,	,	PUNCT
bionys-641	355	25	m.	m.	NOUN
bionys-641	355	26	(	(	PUNCT
bionys-641	355	27	2016	2016	NUM
bionys-641	355	28	)	)	PUNCT
bionys-641	355	29	.	.	PUNCT
bionys-641	356	1	soluble	soluble	ADJ
bionys-641	356	2	tl1a	tl1a	NOUN
bionys-641	356	3	is	be	AUX
bionys-641	356	4	sufficient	sufficient	ADJ
bionys-641	356	5	for	for	ADP
bionys-641	356	6	activation	activation	NOUN
bionys-641	356	7	of	of	ADP
bionys-641	356	8	death	death	NOUN
bionys-641	356	9	receptor	receptor	NOUN
bionys-641	356	10	3	3	NUM
bionys-641	356	11	.	.	PUNCT
bionys-641	357	1	the	the	DET
bionys-641	357	2	febs	febs	NOUN
bionys-641	357	3	journal	journal	NOUN
bionys-641	357	4	,	,	PUNCT
bionys-641	357	5	283(2	283(2	NUM
bionys-641	357	6	)	)	PUNCT
bionys-641	357	7	,	,	PUNCT
bionys-641	357	8	323–336	323–336	NUM
bionys-641	357	9	.	.	PUNCT
bionys-641	358	1	https://doi.org/https://doi.org/10.1111/febs.13576	https://doi.org/https://doi.org/10.1111/febs.13576	PROPN
bionys-641	358	2	brentnall	brentnall	PROPN
bionys-641	358	3	,	,	PUNCT
bionys-641	358	4	m.	m.	NOUN
bionys-641	358	5	,	,	PUNCT
bionys-641	358	6	rodriguez	rodriguez	NOUN
bionys-641	358	7	-	-	PUNCT
bionys-641	358	8	menocal	menocal	ADJ
bionys-641	358	9	,	,	PUNCT
bionys-641	358	10	l.	l.	PROPN
bionys-641	358	11	,	,	PUNCT
bionys-641	358	12	de	de	X
bionys-641	358	13	guevara	guevara	PROPN
bionys-641	358	14	,	,	PUNCT
bionys-641	358	15	r.l	r.l	PROPN
bionys-641	358	16	.	.	PROPN
bionys-641	358	17	,	,	PUNCT
bionys-641	358	18	cepero	cepero	PROPN
bionys-641	358	19	,	,	PUNCT
bionys-641	358	20	e.	e.	PROPN
bionys-641	358	21	,	,	PUNCT
bionys-641	358	22	&	&	CCONJ
bionys-641	358	23	boise	boise	PROPN
bionys-641	358	24	,	,	PUNCT
bionys-641	358	25	l.h	l.h	PROPN
bionys-641	358	26	.	.	PROPN
bionys-641	358	27	(	(	PUNCT
bionys-641	358	28	2013	2013	NUM
bionys-641	358	29	)	)	PUNCT
bionys-641	358	30	.	.	PUNCT
bionys-641	359	1	caspase-9	caspase-9	PROPN
bionys-641	359	2	,	,	PUNCT
bionys-641	359	3	caspase-3	caspase-3	NUM
bionys-641	359	4	and	and	CCONJ
bionys-641	359	5	caspase-7	caspase-7	NUM
bionys-641	359	6	have	have	VERB
bionys-641	359	7	distinct	distinct	ADJ
bionys-641	359	8	roles	role	NOUN
bionys-641	359	9	during	during	ADP
bionys-641	359	10	intrinsic	intrinsic	ADJ
bionys-641	359	11	apoptosis	apoptosis	NOUN
bionys-641	359	12	.	.	PUNCT
bionys-641	360	1	bmc	bmc	NOUN
bionys-641	360	2	cell	cell	NOUN
bionys-641	360	3	biology	biology	NOUN
bionys-641	360	4	,	,	PUNCT
bionys-641	360	5	14(1	14(1	NUM
bionys-641	360	6	)	)	PUNCT
bionys-641	360	7	,	,	PUNCT
bionys-641	360	8	32	32	NUM
bionys-641	360	9	.	.	PUNCT
bionys-641	361	1	https://doi.org/10.1186/1471-2121-14-32	https://doi.org/10.1186/1471-2121-14-32	PROPN
bionys-641	361	2	budillon	budillon	PROPN
bionys-641	361	3	,	,	PUNCT
bionys-641	361	4	a.	a.	NOUN
bionys-641	361	5	,	,	PUNCT
bionys-641	361	6	carbone	carbone	NOUN
bionys-641	361	7	,	,	PUNCT
bionys-641	361	8	c.	c.	PROPN
bionys-641	361	9	,	,	PUNCT
bionys-641	361	10	&	&	CCONJ
bionys-641	361	11	di	di	PROPN
bionys-641	361	12	gennaro	gennaro	PROPN
bionys-641	361	13	,	,	PUNCT
bionys-641	361	14	e.	e.	PROPN
bionys-641	361	15	(	(	PUNCT
bionys-641	361	16	2013	2013	NUM
bionys-641	361	17	)	)	PUNCT
bionys-641	361	18	.	.	PUNCT
bionys-641	362	1	tissue	tissue	NOUN
bionys-641	362	2	transglutaminase	transglutaminase	NOUN
bionys-641	362	3	:	:	PUNCT
bionys-641	362	4	a	a	DET
bionys-641	362	5	new	new	ADJ
bionys-641	362	6	target	target	NOUN
bionys-641	362	7	to	to	PART
bionys-641	362	8	reverse	reverse	VERB
bionys-641	362	9	cancer	cancer	NOUN
bionys-641	362	10	drug	drug	NOUN
bionys-641	362	11	resistance	resistance	NOUN
bionys-641	362	12	.	.	PUNCT
bionys-641	363	1	amino	amino	ADJ
bionys-641	363	2	acids	acid	NOUN
bionys-641	363	3	,	,	PUNCT
bionys-641	363	4	44(1	44(1	PROPN
bionys-641	363	5	)	)	PUNCT
bionys-641	363	6	,	,	PUNCT
bionys-641	363	7	63–72	63–72	NUM
bionys-641	363	8	.	.	PUNCT
bionys-641	364	1	https://doi.org/10.1007/s00726-011-1167-9	https://doi.org/10.1007/s00726-011-1167-9	NUM
bionys-641	364	2	cavalcante	cavalcante	PROPN
bionys-641	364	3	,	,	PUNCT
bionys-641	364	4	g.c	g.c	PROPN
bionys-641	364	5	.	.	PROPN
bionys-641	364	6	,	,	PUNCT
bionys-641	364	7	schaan	schaan	PROPN
bionys-641	364	8	,	,	PUNCT
bionys-641	364	9	a.p	a.p	PROPN
bionys-641	364	10	.	.	PROPN
bionys-641	364	11	,	,	PUNCT
bionys-641	364	12	cabral	cabral	PROPN
bionys-641	364	13	,	,	PUNCT
bionys-641	364	14	g.f	g.f	PROPN
bionys-641	364	15	.	.	PROPN
bionys-641	364	16	,	,	PUNCT
bionys-641	364	17	santana	santana	PROPN
bionys-641	364	18	-	-	PUNCT
bionys-641	364	19	da	da	PROPN
bionys-641	364	20	-	-	PUNCT
bionys-641	364	21	silva	silva	NOUN
bionys-641	364	22	,	,	PUNCT
bionys-641	364	23	m.n	m.n	PROPN
bionys-641	364	24	.	.	PROPN
bionys-641	364	25	,	,	PUNCT
bionys-641	364	26	pinto	pinto	NOUN
bionys-641	364	27	,	,	PUNCT
bionys-641	364	28	p.	p.	NOUN
bionys-641	364	29	,	,	PUNCT
bionys-641	364	30	vidal	vidal	PROPN
bionys-641	364	31	,	,	PUNCT
bionys-641	364	32	a.f	a.f	PROPN
bionys-641	364	33	.	.	PROPN
bionys-641	364	34	,	,	PUNCT
bionys-641	364	35	&	&	CCONJ
bionys-641	364	36	ribeiro	ribeiro	PROPN
bionys-641	364	37	-	-	PUNCT
bionys-641	364	38	dos	dos	PROPN
bionys-641	364	39	-	-	PUNCT
bionys-641	364	40	santos	santo	NOUN
bionys-641	364	41	,	,	PUNCT
bionys-641	364	42	â	â	NOUN
bionys-641	364	43	.	.	PROPN
bionys-641	364	44	(	(	PUNCT
bionys-641	364	45	2019	2019	NUM
bionys-641	364	46	)	)	PUNCT
bionys-641	364	47	.	.	PUNCT
bionys-641	365	1	a	a	DET
bionys-641	365	2	cell	cell	NOUN
bionys-641	365	3	’s	’s	PART
bionys-641	365	4	fate	fate	NOUN
bionys-641	365	5	:	:	PUNCT
bionys-641	365	6	an	an	DET
bionys-641	365	7	overview	overview	NOUN
bionys-641	365	8	of	of	ADP
bionys-641	365	9	the	the	DET
bionys-641	365	10	molecular	molecular	ADJ
bionys-641	365	11	biology	biology	NOUN
bionys-641	365	12	and	and	CCONJ
bionys-641	365	13	genetics	genetic	NOUN
bionys-641	365	14	of	of	ADP
bionys-641	365	15	apoptosis	apoptosis	NOUN
bionys-641	365	16	.	.	PUNCT
bionys-641	366	1	international	international	ADJ
bionys-641	366	2	journal	journal	NOUN
bionys-641	366	3	of	of	ADP
bionys-641	366	4	molecular	molecular	ADJ
bionys-641	366	5	sciences	science	NOUN
bionys-641	366	6	,	,	PUNCT
bionys-641	366	7	20(17	20(17	NUM
bionys-641	366	8	)	)	PUNCT
bionys-641	366	9	,	,	PUNCT
bionys-641	366	10	4133	4133	NUM
bionys-641	366	11	.	.	PUNCT
bionys-641	367	1	https://doi.org/10.3390/	https://doi.org/10.3390/	PROPN
bionys-641	367	2	ijms20174133	ijms20174133	PROPN
bionys-641	367	3	chen	chen	PROPN
bionys-641	367	4	,	,	PUNCT
bionys-641	367	5	j.	j.	PROPN
bionys-641	367	6	,	,	PUNCT
bionys-641	367	7	kos	kos	PROPN
bionys-641	367	8	,	,	PUNCT
bionys-641	367	9	r.	r.	PROPN
bionys-641	367	10	,	,	PUNCT
bionys-641	367	11	garssen	garssen	NOUN
bionys-641	367	12	,	,	PUNCT
bionys-641	367	13	j.	j.	PROPN
bionys-641	367	14	,	,	PUNCT
bionys-641	367	15	&	&	CCONJ
bionys-641	367	16	redegeld	redegeld	VERB
bionys-641	367	17	,	,	PUNCT
bionys-641	367	18	f.	f.	PROPN
bionys-641	367	19	(	(	PUNCT
bionys-641	367	20	2019	2019	NUM
bionys-641	367	21	)	)	PUNCT
bionys-641	367	22	.	.	PUNCT
bionys-641	368	1	molecular	molecular	ADJ
bionys-641	368	2	insights	insight	NOUN
bionys-641	368	3	into	into	ADP
bionys-641	368	4	the	the	DET
bionys-641	368	5	mechanism	mechanism	NOUN
bionys-641	368	6	of	of	ADP
bionys-641	368	7	necroptosis	necroptosis	NOUN
bionys-641	368	8	:	:	PUNCT
bionys-641	368	9	the	the	DET
bionys-641	368	10	necrosome	necrosome	NOUN
bionys-641	368	11	as	as	ADP
bionys-641	368	12	a	a	DET
bionys-641	368	13	potential	potential	ADJ
bionys-641	368	14	therapeutic	therapeutic	ADJ
bionys-641	368	15	target	target	NOUN
bionys-641	368	16	.	.	PUNCT
bionys-641	369	1	cells	cell	NOUN
bionys-641	369	2	,	,	PUNCT
bionys-641	369	3	8(12	8(12	NUM
bionys-641	369	4	)	)	PUNCT
bionys-641	369	5	,	,	PUNCT
bionys-641	369	6	1486	1486	NUM
bionys-641	369	7	.	.	PUNCT
bionys-641	370	1	https://doi	https://doi	X
bionys-641	370	2	.	.	PUNCT
bionys-641	370	3	org/10.3390	org/10.3390	PROPN
bionys-641	370	4	/	/	SYM
bionys-641	370	5	cells8121486	cells8121486	PROPN
bionys-641	370	6	cho	cho	PROPN
bionys-641	370	7	,	,	PUNCT
bionys-641	370	8	y.s	y.s	PROPN
bionys-641	370	9	.	.	PROPN
bionys-641	370	10	,	,	PUNCT
bionys-641	370	11	challa	challa	PROPN
bionys-641	370	12	,	,	PUNCT
bionys-641	370	13	s.	s.	PROPN
bionys-641	370	14	,	,	PUNCT
bionys-641	370	15	moquin	moquin	PROPN
bionys-641	370	16	,	,	PUNCT
bionys-641	370	17	d.	d.	PROPN
bionys-641	370	18	,	,	PUNCT
bionys-641	370	19	genga	genga	PROPN
bionys-641	370	20	,	,	PUNCT
bionys-641	370	21	r.	r.	PROPN
bionys-641	370	22	,	,	PUNCT
bionys-641	370	23	ray	ray	PROPN
bionys-641	370	24	,	,	PUNCT
bionys-641	370	25	t.d	t.d	PROPN
bionys-641	370	26	.	.	PROPN
bionys-641	370	27	,	,	PUNCT
bionys-641	370	28	guildford	guildford	PROPN
bionys-641	370	29	,	,	PUNCT
bionys-641	370	30	m.	m.	NOUN
bionys-641	370	31	,	,	PUNCT
bionys-641	370	32	&	&	CCONJ
bionys-641	370	33	chan	chan	PROPN
bionys-641	370	34	,	,	PUNCT
bionys-641	370	35	f.k.-m	f.k.-m	PROPN
bionys-641	370	36	.	.	PUNCT
bionys-641	371	1	(	(	PUNCT
bionys-641	371	2	2009	2009	NUM
bionys-641	371	3	)	)	PUNCT
bionys-641	371	4	.	.	PUNCT
bionys-641	372	1	phosphorylation	phosphorylation	NOUN
bionys-641	372	2	-	-	PUNCT
bionys-641	372	3	driven	drive	VERB
bionys-641	372	4	assembly	assembly	NOUN
bionys-641	372	5	of	of	ADP
bionys-641	372	6	the	the	DET
bionys-641	372	7	rip1	rip1	PROPN
bionys-641	372	8	-	-	PUNCT
bionys-641	372	9	rip3	rip3	PROPN
bionys-641	372	10	complex	complex	NOUN
bionys-641	372	11	regulates	regulate	VERB
bionys-641	372	12	programmed	program	VERB
bionys-641	372	13	necrosis	necrosis	NOUN
bionys-641	372	14	and	and	CCONJ
bionys-641	372	15	virusinduced	virusinduce	VERB
bionys-641	372	16	inflammation	inflammation	NOUN
bionys-641	372	17	.	.	PUNCT
bionys-641	373	1	cell	cell	NOUN
bionys-641	373	2	,	,	PUNCT
bionys-641	373	3	137(6	137(6	NUM
bionys-641	373	4	)	)	PUNCT
bionys-641	373	5	,	,	PUNCT
bionys-641	373	6	1112–1123	1112–1123	NUM
bionys-641	373	7	.	.	PUNCT
bionys-641	374	1	https://doi.org/10.1016/j.cell.2009.05.037	https://doi.org/10.1016/j.cell.2009.05.037	NUM
bionys-641	374	2	choi	choi	NOUN
bionys-641	374	3	,	,	PUNCT
bionys-641	374	4	y.-j	y.-j	PROPN
bionys-641	374	5	.	.	PROPN
bionys-641	374	6	,	,	PUNCT
bionys-641	374	7	yun	yun	PROPN
bionys-641	374	8	,	,	PUNCT
bionys-641	374	9	s.h	s.h	PROPN
bionys-641	374	10	.	.	PROPN
bionys-641	374	11	,	,	PUNCT
bionys-641	374	12	yu	yu	PROPN
bionys-641	374	13	,	,	PUNCT
bionys-641	374	14	j.	j.	PROPN
bionys-641	374	15	,	,	PUNCT
bionys-641	374	16	mun	mun	PROPN
bionys-641	374	17	,	,	PUNCT
bionys-641	374	18	y.	y.	PROPN
bionys-641	374	19	,	,	PUNCT
bionys-641	374	20	lee	lee	PROPN
bionys-641	374	21	,	,	PUNCT
bionys-641	374	22	w.	w.	PROPN
bionys-641	374	23	,	,	PUNCT
bionys-641	374	24	park	park	NOUN
bionys-641	374	25	,	,	PUNCT
bionys-641	374	26	c.j	c.j	PROPN
bionys-641	374	27	.	.	PROPN
bionys-641	374	28	,	,	PUNCT
bionys-641	374	29	han	han	PROPN
bionys-641	374	30	,	,	PUNCT
bionys-641	374	31	b.w	b.w	PROPN
bionys-641	374	32	.	.	PROPN
bionys-641	374	33	,	,	PUNCT
bionys-641	374	34	&	&	CCONJ
bionys-641	374	35	lee	lee	PROPN
bionys-641	374	36	,	,	PUNCT
bionys-641	374	37	b.-h	b.-h	PROPN
bionys-641	374	38	.	.	PUNCT
bionys-641	375	1	(	(	PUNCT
bionys-641	375	2	2023	2023	NUM
bionys-641	375	3	)	)	PUNCT
bionys-641	375	4	.	.	PUNCT
bionys-641	376	1	chaperone	chaperone	NOUN
bionys-641	376	2	-	-	PUNCT
bionys-641	376	3	mediated	mediate	VERB
bionys-641	376	4	autophagy	autophagy	ADJ
bionys-641	376	5	dysregulation	dysregulation	NOUN
bionys-641	376	6	during	during	ADP
bionys-641	376	7	aging	age	VERB
bionys-641	376	8	impairs	impair	VERB
bionys-641	376	9	hepatic	hepatic	ADJ
bionys-641	376	10	fatty	fatty	NOUN
bionys-641	376	11	acid	acid	NOUN
bionys-641	376	12	oxidation	oxidation	NOUN
bionys-641	376	13	via	via	ADP
bionys-641	376	14	accumulation	accumulation	NOUN
bionys-641	376	15	of	of	ADP
bionys-641	376	16	ncor1	ncor1	PROPN
bionys-641	376	17	.	.	PUNCT
bionys-641	377	1	molecular	molecular	ADJ
bionys-641	377	2	metabolism	metabolism	NOUN
bionys-641	377	3	,	,	PUNCT
bionys-641	377	4	76	76	NUM
bionys-641	377	5	,	,	PUNCT
bionys-641	377	6	101784	101784	NUM
bionys-641	377	7	.	.	PUNCT
bionys-641	378	1	https://doi.org/10.1016/j	https://doi.org/10.1016/j	NOUN
bionys-641	378	2	.	.	PUNCT
bionys-641	379	1	biologica	biologica	PROPN
bionys-641	379	2	nyssana	nyssana	PROPN
bionys-641	379	3	●	●	PUNCT
bionys-641	379	4	16	16	NUM
bionys-641	379	5	(	(	PUNCT
bionys-641	379	6	2	2	NUM
bionys-641	379	7	)	)	PUNCT
bionys-641	379	8	december	december	PROPN
bionys-641	379	9	2025	2025	NUM
bionys-641	379	10	:	:	PUNCT
bionys-641	379	11	liana	liana	NOUN
bionys-641	379	12	et	et	PROPN
bionys-641	379	13	al	al	PROPN
bionys-641	379	14	.	.	PUNCT
bionys-641	380	1	●	●	PUNCT
bionys-641	380	2	cell	cell	NOUN
bionys-641	380	3	deaths	death	NOUN
bionys-641	380	4	and	and	CCONJ
bionys-641	380	5	their	their	PRON
bionys-641	380	6	associated	associate	VERB
bionys-641	380	7	mechanisms	mechanism	NOUN
bionys-641	380	8	molmet.2023.101784	molmet.2023.101784	NOUN
bionys-641	380	9	conrad	conrad	PROPN
bionys-641	380	10	,	,	PUNCT
bionys-641	380	11	m.	m.	NOUN
bionys-641	380	12	,	,	PUNCT
bionys-641	380	13	angeli	angeli	PROPN
bionys-641	380	14	,	,	PUNCT
bionys-641	380	15	j.p.f	j.p.f	PROPN
bionys-641	380	16	.	.	PROPN
bionys-641	380	17	,	,	PUNCT
bionys-641	380	18	vandenabeele	vandenabeele	PROPN
bionys-641	380	19	,	,	PUNCT
bionys-641	380	20	p.	p.	PROPN
bionys-641	380	21	,	,	PUNCT
bionys-641	380	22	&	&	CCONJ
bionys-641	380	23	stockwell	stockwell	PROPN
bionys-641	380	24	,	,	PUNCT
bionys-641	380	25	b.r	b.r	PROPN
bionys-641	380	26	.	.	PROPN
bionys-641	380	27	(	(	PUNCT
bionys-641	380	28	2016	2016	NUM
bionys-641	380	29	)	)	PUNCT
bionys-641	380	30	.	.	PUNCT
bionys-641	381	1	regulated	regulate	VERB
bionys-641	381	2	necrosis	necrosis	NOUN
bionys-641	381	3	:	:	PUNCT
bionys-641	381	4	disease	disease	NOUN
bionys-641	381	5	relevance	relevance	NOUN
bionys-641	381	6	and	and	CCONJ
bionys-641	381	7	therapeutic	therapeutic	ADJ
bionys-641	381	8	opportunities	opportunity	NOUN
bionys-641	381	9	.	.	PUNCT
bionys-641	382	1	nature	nature	NOUN
bionys-641	382	2	reviews	review	NOUN
bionys-641	382	3	.	.	PUNCT
bionys-641	383	1	drug	drug	NOUN
bionys-641	383	2	discovery	discovery	PROPN
bionys-641	383	3	,	,	PUNCT
bionys-641	383	4	15(5	15(5	NUM
bionys-641	383	5	)	)	PUNCT
bionys-641	383	6	,	,	PUNCT
bionys-641	383	7	348–366	348–366	NUM
bionys-641	383	8	.	.	PUNCT
bionys-641	384	1	https://	https://	PROPN
bionys-641	384	2	doi.org/10.1038/nrd.2015.6	doi.org/10.1038/nrd.2015.6	PROPN
bionys-641	384	3	d’arcy	d’arcy	PROPN
bionys-641	384	4	,	,	PUNCT
bionys-641	384	5	m.s	m.s	PROPN
bionys-641	384	6	.	.	PROPN
bionys-641	384	7	(	(	PUNCT
bionys-641	384	8	2019	2019	NUM
bionys-641	384	9	)	)	PUNCT
bionys-641	384	10	.	.	PUNCT
bionys-641	385	1	cell	cell	NOUN
bionys-641	385	2	death	death	NOUN
bionys-641	385	3	:	:	PUNCT
bionys-641	385	4	a	a	DET
bionys-641	385	5	review	review	NOUN
bionys-641	385	6	of	of	ADP
bionys-641	385	7	the	the	DET
bionys-641	385	8	major	major	ADJ
bionys-641	385	9	forms	form	NOUN
bionys-641	385	10	of	of	ADP
bionys-641	385	11	apoptosis	apoptosis	NOUN
bionys-641	385	12	,	,	PUNCT
bionys-641	385	13	necrosis	necrosis	NOUN
bionys-641	385	14	and	and	CCONJ
bionys-641	385	15	autophagy	autophagy	NOUN
bionys-641	385	16	.	.	PUNCT
bionys-641	386	1	cell	cell	NOUN
bionys-641	386	2	biology	biology	NOUN
bionys-641	386	3	international	international	PROPN
bionys-641	386	4	,	,	PUNCT
bionys-641	386	5	43(6	43(6	NOUN
bionys-641	386	6	)	)	PUNCT
bionys-641	386	7	,	,	PUNCT
bionys-641	386	8	582–592	582–592	NUM
bionys-641	386	9	.	.	PUNCT
bionys-641	387	1	https://	https://	PROPN
bionys-641	387	2	doi.org/10.1002/cbin.11137	doi.org/10.1002/cbin.11137	PROPN
bionys-641	387	3	degterev	degterev	PROPN
bionys-641	387	4	,	,	PUNCT
bionys-641	387	5	a.	a.	PROPN
bionys-641	387	6	,	,	PUNCT
bionys-641	387	7	huang	huang	PROPN
bionys-641	387	8	,	,	PUNCT
bionys-641	387	9	z.	z.	PROPN
bionys-641	387	10	,	,	PUNCT
bionys-641	387	11	boyce	boyce	PROPN
bionys-641	387	12	,	,	PUNCT
bionys-641	387	13	m.	m.	NOUN
bionys-641	387	14	,	,	PUNCT
bionys-641	387	15	li	li	PROPN
bionys-641	387	16	,	,	PUNCT
bionys-641	387	17	y.	y.	PROPN
bionys-641	387	18	,	,	PUNCT
bionys-641	387	19	jagtap	jagtap	NOUN
bionys-641	387	20	,	,	PUNCT
bionys-641	387	21	p.	p.	PROPN
bionys-641	387	22	,	,	PUNCT
bionys-641	387	23	mizushima	mizushima	PROPN
bionys-641	387	24	,	,	PUNCT
bionys-641	387	25	n.	n.	PROPN
bionys-641	387	26	,	,	PUNCT
bionys-641	387	27	cuny	cuny	PROPN
bionys-641	387	28	,	,	PUNCT
bionys-641	387	29	g.d	g.d	PROPN
bionys-641	387	30	.	.	PROPN
bionys-641	387	31	,	,	PUNCT
bionys-641	387	32	mitchison	mitchison	PROPN
bionys-641	387	33	,	,	PUNCT
bionys-641	387	34	t.j	t.j	PROPN
bionys-641	387	35	.	.	PROPN
bionys-641	387	36	,	,	PUNCT
bionys-641	387	37	moskowitz	moskowitz	PROPN
bionys-641	387	38	,	,	PUNCT
bionys-641	387	39	m.a	m.a	PROPN
bionys-641	387	40	.	.	PROPN
bionys-641	387	41	,	,	PUNCT
bionys-641	387	42	&	&	CCONJ
bionys-641	387	43	yuan	yuan	PROPN
bionys-641	387	44	,	,	PUNCT
bionys-641	387	45	j.	j.	PROPN
bionys-641	387	46	(	(	PUNCT
bionys-641	387	47	2005	2005	NUM
bionys-641	387	48	)	)	PUNCT
bionys-641	387	49	.	.	PUNCT
bionys-641	388	1	chemical	chemical	ADJ
bionys-641	388	2	inhibitor	inhibitor	NOUN
bionys-641	388	3	of	of	ADP
bionys-641	388	4	nonapoptotic	nonapoptotic	ADJ
bionys-641	388	5	cell	cell	NOUN
bionys-641	388	6	death	death	NOUN
bionys-641	388	7	with	with	ADP
bionys-641	388	8	therapeutic	therapeutic	ADJ
bionys-641	388	9	potential	potential	NOUN
bionys-641	388	10	for	for	ADP
bionys-641	388	11	ischemic	ischemic	ADJ
bionys-641	388	12	brain	brain	NOUN
bionys-641	388	13	injury	injury	NOUN
bionys-641	388	14	.	.	PUNCT
bionys-641	389	1	nature	nature	NOUN
bionys-641	389	2	chemical	chemical	PROPN
bionys-641	389	3	biology	biology	NOUN
bionys-641	389	4	,	,	PUNCT
bionys-641	389	5	1(2	1(2	NUM
bionys-641	389	6	)	)	PUNCT
bionys-641	389	7	,	,	PUNCT
bionys-641	389	8	112–119	112–119	NUM
bionys-641	389	9	.	.	PUNCT
bionys-641	390	1	https://doi.org/10.1038/	https://doi.org/10.1038/	NOUN
bionys-641	390	2	nchembio711	nchembio711	PROPN
bionys-641	390	3	denton	denton	PROPN
bionys-641	390	4	,	,	PUNCT
bionys-641	390	5	d.	d.	PROPN
bionys-641	390	6	&	&	CCONJ
bionys-641	390	7	kumar	kumar	PROPN
bionys-641	390	8	,	,	PUNCT
bionys-641	390	9	s.	s.	PROPN
bionys-641	390	10	(	(	PUNCT
bionys-641	390	11	2019	2019	NUM
bionys-641	390	12	)	)	PUNCT
bionys-641	390	13	.	.	PUNCT
bionys-641	391	1	autophagydependent	autophagydependent	NOUN
bionys-641	391	2	cell	cell	NOUN
bionys-641	391	3	death	death	NOUN
bionys-641	391	4	.	.	PUNCT
bionys-641	392	1	cell	cell	NOUN
bionys-641	392	2	death	death	NOUN
bionys-641	392	3	and	and	CCONJ
bionys-641	392	4	differentiation	differentiation	NOUN
bionys-641	392	5	,	,	PUNCT
bionys-641	392	6	26(4	26(4	NUM
bionys-641	392	7	)	)	PUNCT
bionys-641	392	8	,	,	PUNCT
bionys-641	392	9	605–616	605–616	NUM
bionys-641	392	10	.	.	PUNCT
bionys-641	393	1	https://doi.org/10.1038/s41418018-0252-y	https://doi.org/10.1038/s41418018-0252-y	PRON
bionys-641	393	2	díaz	díaz	NOUN
bionys-641	393	3	-	-	PUNCT
bionys-641	393	4	mendoza	mendoza	PROPN
bionys-641	393	5	,	,	PUNCT
bionys-641	393	6	m.j	m.j	PROPN
bionys-641	393	7	.	.	PROPN
bionys-641	393	8	,	,	PUNCT
bionys-641	393	9	lorda	lorda	PROPN
bionys-641	393	10	-	-	PUNCT
bionys-641	393	11	diez	diez	PROPN
bionys-641	393	12	,	,	PUNCT
bionys-641	393	13	c.i	c.i	PROPN
bionys-641	393	14	.	.	PROPN
bionys-641	393	15	,	,	PUNCT
bionys-641	393	16	montero	montero	PROPN
bionys-641	393	17	,	,	PUNCT
bionys-641	393	18	j.a	j.a	PROPN
bionys-641	393	19	.	.	PROPN
bionys-641	393	20	,	,	PUNCT
bionys-641	393	21	garcía	garcía	NOUN
bionys-641	393	22	-	-	PUNCT
bionys-641	393	23	porrero	porrero	NOUN
bionys-641	393	24	,	,	PUNCT
bionys-641	393	25	j.a	j.a	PROPN
bionys-641	393	26	.	.	PROPN
bionys-641	393	27	,	,	PUNCT
bionys-641	393	28	&	&	CCONJ
bionys-641	393	29	hurlé	hurlé	PROPN
bionys-641	393	30	,	,	PUNCT
bionys-641	393	31	j.m	j.m	PROPN
bionys-641	393	32	.	.	PROPN
bionys-641	393	33	(	(	PUNCT
bionys-641	393	34	2013	2013	NUM
bionys-641	393	35	)	)	PUNCT
bionys-641	393	36	.	.	PUNCT
bionys-641	394	1	interdigital	interdigital	ADJ
bionys-641	394	2	cell	cell	NOUN
bionys-641	394	3	death	death	NOUN
bionys-641	394	4	in	in	ADP
bionys-641	394	5	the	the	DET
bionys-641	394	6	embryonic	embryonic	ADJ
bionys-641	394	7	limb	limb	NOUN
bionys-641	394	8	is	be	AUX
bionys-641	394	9	associated	associate	VERB
bionys-641	394	10	with	with	ADP
bionys-641	394	11	depletion	depletion	NOUN
bionys-641	394	12	of	of	ADP
bionys-641	394	13	reelin	reelin	NOUN
bionys-641	394	14	in	in	ADP
bionys-641	394	15	the	the	DET
bionys-641	394	16	extracellular	extracellular	ADJ
bionys-641	394	17	matrix	matrix	NOUN
bionys-641	394	18	.	.	PUNCT
bionys-641	395	1	cell	cell	NOUN
bionys-641	395	2	death	death	NOUN
bionys-641	395	3	&	&	CCONJ
bionys-641	395	4	disease	disease	PROPN
bionys-641	395	5	,	,	PUNCT
bionys-641	395	6	4(9	4(9	NUM
bionys-641	395	7	)	)	PUNCT
bionys-641	395	8	,	,	PUNCT
bionys-641	395	9	e800	e800	PROPN
bionys-641	395	10	.	.	PUNCT
bionys-641	396	1	https://doi.org/10.1038/cddis.2013.322	https://doi.org/10.1038/cddis.2013.322	PROPN
bionys-641	396	2	dice	dice	NOUN
bionys-641	396	3	,	,	PUNCT
bionys-641	396	4	j.f	j.f	PROPN
bionys-641	396	5	.	.	PROPN
bionys-641	396	6	(	(	PUNCT
bionys-641	396	7	2007	2007	NUM
bionys-641	396	8	)	)	PUNCT
bionys-641	396	9	.	.	PUNCT
bionys-641	397	1	chaperone	chaperone	NOUN
bionys-641	397	2	-	-	PUNCT
bionys-641	397	3	mediated	mediate	VERB
bionys-641	397	4	autophagy	autophagy	NOUN
bionys-641	397	5	.	.	PUNCT
bionys-641	398	1	autophagy	autophagy	NOUN
bionys-641	398	2	,	,	PUNCT
bionys-641	398	3	3(4	3(4	NUM
bionys-641	398	4	)	)	PUNCT
bionys-641	398	5	,	,	PUNCT
bionys-641	398	6	295–299	295–299	NUM
bionys-641	398	7	.	.	PUNCT
bionys-641	399	1	https://doi.org/10.4161/	https://doi.org/10.4161/	PROPN
bionys-641	399	2	auto.4144	auto.4144	PROPN
bionys-641	399	3	durgan	durgan	NOUN
bionys-641	399	4	,	,	PUNCT
bionys-641	399	5	j.	j.	PROPN
bionys-641	399	6	,	,	PUNCT
bionys-641	399	7	tseng	tseng	PROPN
bionys-641	399	8	,	,	PUNCT
bionys-641	399	9	y.-y	y.-y	PROPN
bionys-641	399	10	.	.	PROPN
bionys-641	399	11	,	,	PUNCT
bionys-641	399	12	hamann	hamann	PROPN
bionys-641	399	13	,	,	PUNCT
bionys-641	399	14	j.c	j.c	PROPN
bionys-641	399	15	.	.	PROPN
bionys-641	399	16	,	,	PUNCT
bionys-641	399	17	domart	domart	PROPN
bionys-641	399	18	,	,	PUNCT
bionys-641	399	19	m.-c	m.-c	NOUN
bionys-641	399	20	.	.	PUNCT
bionys-641	399	21	,	,	PUNCT
bionys-641	399	22	collinson	collinson	PROPN
bionys-641	399	23	,	,	PUNCT
bionys-641	399	24	l.	l.	PROPN
bionys-641	399	25	,	,	PUNCT
bionys-641	399	26	hall	hall	PROPN
bionys-641	399	27	,	,	PUNCT
bionys-641	399	28	a.	a.	NOUN
bionys-641	399	29	,	,	PUNCT
bionys-641	399	30	overholtzer	overholtzer	NOUN
bionys-641	399	31	,	,	PUNCT
bionys-641	399	32	m.	m.	NOUN
bionys-641	399	33	,	,	PUNCT
bionys-641	399	34	&	&	CCONJ
bionys-641	399	35	florey	florey	PROPN
bionys-641	399	36	,	,	PUNCT
bionys-641	399	37	o.	o.	PROPN
bionys-641	399	38	(	(	PUNCT
bionys-641	399	39	2017	2017	NUM
bionys-641	399	40	)	)	PUNCT
bionys-641	399	41	.	.	PUNCT
bionys-641	400	1	mitosis	mitosis	PROPN
bionys-641	400	2	can	can	AUX
bionys-641	400	3	drive	drive	VERB
bionys-641	400	4	cell	cell	NOUN
bionys-641	400	5	cannibalism	cannibalism	NOUN
bionys-641	400	6	through	through	ADP
bionys-641	400	7	entosis	entosis	NOUN
bionys-641	400	8	.	.	PUNCT
bionys-641	401	1	elife	elife	NOUN
bionys-641	401	2	,	,	PUNCT
bionys-641	401	3	6	6	NUM
bionys-641	401	4	,	,	PUNCT
bionys-641	401	5	e27134	e27134	PROPN
bionys-641	401	6	.	.	PROPN
bionys-641	401	7	https://doi.org/10.7554/elife.27134	https://doi.org/10.7554/elife.27134	PROPN
bionys-641	401	8	elliott	elliott	PROPN
bionys-641	401	9	,	,	PUNCT
bionys-641	401	10	m.r	m.r	PROPN
bionys-641	401	11	.	.	PROPN
bionys-641	401	12	&	&	CCONJ
bionys-641	401	13	ravichandran	ravichandran	PROPN
bionys-641	401	14	,	,	PUNCT
bionys-641	401	15	k.s	k.s	PROPN
bionys-641	401	16	.	.	PROPN
bionys-641	401	17	(	(	PUNCT
bionys-641	401	18	2010	2010	NUM
bionys-641	401	19	)	)	PUNCT
bionys-641	401	20	.	.	PUNCT
bionys-641	402	1	clearance	clearance	NOUN
bionys-641	402	2	of	of	ADP
bionys-641	402	3	apoptotic	apoptotic	ADJ
bionys-641	402	4	cells	cell	NOUN
bionys-641	402	5	:	:	PUNCT
bionys-641	402	6	implications	implication	NOUN
bionys-641	402	7	in	in	ADP
bionys-641	402	8	health	health	NOUN
bionys-641	402	9	and	and	CCONJ
bionys-641	402	10	disease	disease	NOUN
bionys-641	402	11	.	.	PUNCT
bionys-641	403	1	journal	journal	PROPN
bionys-641	403	2	of	of	ADP
bionys-641	403	3	cell	cell	NOUN
bionys-641	403	4	biology	biology	NOUN
bionys-641	403	5	,	,	PUNCT
bionys-641	403	6	189(7	189(7	NUM
bionys-641	403	7	)	)	PUNCT
bionys-641	403	8	,	,	PUNCT
bionys-641	403	9	1059	1059	NUM
bionys-641	403	10	–	–	PUNCT
bionys-641	403	11	1070	1070	NUM
bionys-641	403	12	.	.	PUNCT
bionys-641	404	1	https://doi.org/10.1083/jcb.201004096	https://doi.org/10.1083/jcb.201004096	PROPN
bionys-641	404	2	engelman	engelman	PROPN
bionys-641	404	3	,	,	PUNCT
bionys-641	404	4	j.a	j.a	PROPN
bionys-641	404	5	.	.	PROPN
bionys-641	404	6	,	,	PUNCT
bionys-641	404	7	luo	luo	PROPN
bionys-641	404	8	,	,	PUNCT
bionys-641	404	9	j.	j.	PROPN
bionys-641	404	10	,	,	PUNCT
bionys-641	404	11	&	&	CCONJ
bionys-641	404	12	cantley	cantley	PROPN
bionys-641	404	13	,	,	PUNCT
bionys-641	404	14	l.c	l.c	PROPN
bionys-641	404	15	.	.	PROPN
bionys-641	404	16	(	(	PUNCT
bionys-641	404	17	2006	2006	NUM
bionys-641	404	18	)	)	PUNCT
bionys-641	404	19	.	.	PUNCT
bionys-641	405	1	the	the	DET
bionys-641	405	2	evolution	evolution	NOUN
bionys-641	405	3	of	of	ADP
bionys-641	405	4	phosphatidylinositol	phosphatidylinositol	NOUN
bionys-641	405	5	3	3	NUM
bionys-641	405	6	-	-	PUNCT
bionys-641	405	7	kinases	kinase	NOUN
bionys-641	405	8	as	as	ADP
bionys-641	405	9	regulators	regulator	NOUN
bionys-641	405	10	of	of	ADP
bionys-641	405	11	growth	growth	NOUN
bionys-641	405	12	and	and	CCONJ
bionys-641	405	13	metabolism	metabolism	NOUN
bionys-641	405	14	.	.	PUNCT
bionys-641	406	1	nature	nature	NOUN
bionys-641	406	2	reviews	review	NOUN
bionys-641	406	3	.	.	PUNCT
bionys-641	407	1	genetics	genetic	NOUN
bionys-641	407	2	,	,	PUNCT
bionys-641	407	3	7(8	7(8	NUM
bionys-641	407	4	)	)	PUNCT
bionys-641	407	5	,	,	PUNCT
bionys-641	407	6	606–619	606–619	NUM
bionys-641	407	7	.	.	PUNCT
bionys-641	408	1	https://doi	https://doi	NOUN
bionys-641	408	2	.	.	PUNCT
bionys-641	408	3	org/10.1038	org/10.1038	PROPN
bionys-641	408	4	/	/	SYM
bionys-641	408	5	nrg1879	nrg1879	ADV
bionys-641	408	6	fathima	fathima	PROPN
bionys-641	408	7	,	,	PUNCT
bionys-641	408	8	s.d	s.d	PROPN
bionys-641	408	9	.	.	PROPN
bionys-641	408	10	,	,	PUNCT
bionys-641	408	11	gururaj	gururaj	ADJ
bionys-641	408	12	,	,	PUNCT
bionys-641	408	13	n.	n.	NOUN
bionys-641	408	14	,	,	PUNCT
bionys-641	408	15	sivapathasundharam	sivapathasundharam	PROPN
bionys-641	408	16	,	,	PUNCT
bionys-641	408	17	b.	b.	PROPN
bionys-641	408	18	,	,	PUNCT
bionys-641	408	19	vennila	vennila	PROPN
bionys-641	408	20	,	,	PUNCT
bionys-641	408	21	a.a	a.a	PROPN
bionys-641	408	22	.	.	PROPN
bionys-641	408	23	,	,	PUNCT
bionys-641	408	24	keerthik	keerthik	PROPN
bionys-641	408	25	lavanya	lavanya	NOUN
bionys-641	408	26	,	,	PUNCT
bionys-641	408	27	m.k	m.k	PROPN
bionys-641	408	28	.	.	PROPN
bionys-641	408	29	,	,	PUNCT
bionys-641	408	30	&	&	CCONJ
bionys-641	408	31	sarayushivani	sarayushivani	PROPN
bionys-641	408	32	,	,	PUNCT
bionys-641	408	33	u.	u.	PROPN
bionys-641	408	34	(	(	PUNCT
bionys-641	408	35	2023	2023	NUM
bionys-641	408	36	)	)	PUNCT
bionys-641	408	37	.	.	PUNCT
bionys-641	409	1	histopathological	histopathological	ADJ
bionys-641	409	2	significance	significance	NOUN
bionys-641	409	3	of	of	ADP
bionys-641	409	4	necrosis	necrosis	NOUN
bionys-641	409	5	in	in	ADP
bionys-641	409	6	oral	oral	ADJ
bionys-641	409	7	lesions	lesion	NOUN
bionys-641	409	8	:	:	PUNCT
bionys-641	409	9	a	a	DET
bionys-641	409	10	review	review	NOUN
bionys-641	409	11	.	.	PUNCT
bionys-641	410	1	journal	journal	NOUN
bionys-641	410	2	of	of	ADP
bionys-641	410	3	oral	oral	ADJ
bionys-641	410	4	and	and	CCONJ
bionys-641	410	5	maxillofacial	maxillofacial	ADJ
bionys-641	410	6	pathology	pathology	NOUN
bionys-641	410	7	,	,	PUNCT
bionys-641	410	8	27(2	27(2	NUM
bionys-641	410	9	)	)	PUNCT
bionys-641	410	10	,	,	PUNCT
bionys-641	410	11	340–347	340–347	NUM
bionys-641	410	12	.	.	PUNCT
bionys-641	411	1	https://doi.org/10.4103/jomfp	https://doi.org/10.4103/jomfp	NOUN
bionys-641	411	2	.	.	PUNCT
bionys-641	412	1	jomfp_39_23	jomfp_39_23	PROPN
bionys-641	412	2	feitelson	feitelson	NOUN
bionys-641	412	3	,	,	PUNCT
bionys-641	412	4	m.	m.	NOUN
bionys-641	412	5	a.	a.	PROPN
bionys-641	412	6	,	,	PUNCT
bionys-641	412	7	arzumanyan	arzumanyan	PROPN
bionys-641	412	8	,	,	PUNCT
bionys-641	412	9	a.	a.	NOUN
bionys-641	412	10	,	,	PUNCT
bionys-641	412	11	kulathinal	kulathinal	PROPN
bionys-641	412	12	,	,	PUNCT
bionys-641	412	13	r.	r.	PROPN
bionys-641	412	14	j.	j.	PROPN
bionys-641	412	15	,	,	PUNCT
bionys-641	412	16	blain	blain	PROPN
bionys-641	412	17	,	,	PUNCT
bionys-641	412	18	s.	s.	PROPN
bionys-641	412	19	w.	w.	PROPN
bionys-641	412	20	,	,	PUNCT
bionys-641	412	21	holcombe	holcombe	PROPN
bionys-641	412	22	,	,	PUNCT
bionys-641	412	23	r.	r.	PROPN
bionys-641	412	24	f.	f.	PROPN
bionys-641	412	25	,	,	PUNCT
bionys-641	412	26	mahajna	mahajna	PROPN
bionys-641	412	27	,	,	PUNCT
bionys-641	412	28	j.	j.	PROPN
bionys-641	412	29	,	,	PUNCT
bionys-641	412	30	marino	marino	PROPN
bionys-641	412	31	,	,	PUNCT
bionys-641	412	32	m.	m.	NOUN
bionys-641	412	33	,	,	PUNCT
bionys-641	412	34	martinez	martinez	PROPN
bionys-641	412	35	-	-	PUNCT
bionys-641	412	36	chantar	chantar	NOUN
bionys-641	412	37	,	,	PUNCT
bionys-641	412	38	m.	m.	NOUN
bionys-641	412	39	l.	l.	PROPN
bionys-641	412	40	,	,	PUNCT
bionys-641	412	41	nawroth	nawroth	PROPN
bionys-641	412	42	,	,	PUNCT
bionys-641	412	43	r.	r.	PROPN
bionys-641	412	44	,	,	PUNCT
bionys-641	412	45	sanchez	sanchez	PROPN
bionys-641	412	46	-	-	PUNCT
bionys-641	412	47	garcia	garcia	PROPN
bionys-641	412	48	,	,	PUNCT
bionys-641	412	49	i.	i.	PROPN
bionys-641	412	50	,	,	PUNCT
bionys-641	412	51	sharma	sharma	PROPN
bionys-641	412	52	,	,	PUNCT
bionys-641	412	53	d.	d.	PROPN
bionys-641	412	54	,	,	PUNCT
bionys-641	412	55	saxena	saxena	PROPN
bionys-641	412	56	,	,	PUNCT
bionys-641	412	57	n.	n.	PROPN
bionys-641	412	58	k.	k.	PROPN
bionys-641	412	59	,	,	PUNCT
bionys-641	412	60	singh	singh	PROPN
bionys-641	412	61	,	,	PUNCT
bionys-641	412	62	n.	n.	NOUN
bionys-641	412	63	,	,	PUNCT
bionys-641	412	64	vlachostergios	vlachostergio	NOUN
bionys-641	412	65	,	,	PUNCT
bionys-641	412	66	p.	p.	PROPN
bionys-641	412	67	j.	j.	PROPN
bionys-641	412	68	,	,	PUNCT
bionys-641	412	69	guo	guo	PROPN
bionys-641	412	70	,	,	PUNCT
bionys-641	412	71	s.	s.	PROPN
bionys-641	412	72	,	,	PUNCT
bionys-641	412	73	honoki	honoki	PROPN
bionys-641	412	74	,	,	PUNCT
bionys-641	412	75	k.	k.	PROPN
bionys-641	412	76	,	,	PUNCT
bionys-641	412	77	fujii	fujii	PROPN
bionys-641	412	78	,	,	PUNCT
bionys-641	412	79	h.	h.	PROPN
bionys-641	412	80	,	,	PUNCT
bionys-641	412	81	georgakilas	georgakila	NOUN
bionys-641	412	82	,	,	PUNCT
bionys-641	412	83	a.	a.	NOUN
bionys-641	412	84	g.	g.	PROPN
bionys-641	412	85	,	,	PUNCT
bionys-641	412	86	bilsland	bilsland	PROPN
bionys-641	412	87	,	,	PUNCT
bionys-641	412	88	a.	a.	NOUN
bionys-641	412	89	,	,	PUNCT
bionys-641	412	90	amedei	amedei	NOUN
bionys-641	412	91	,	,	PUNCT
bionys-641	412	92	a.	a.	NOUN
bionys-641	412	93	,	,	PUNCT
bionys-641	412	94	niccolai	niccolai	PROPN
bionys-641	412	95	,	,	PUNCT
bionys-641	412	96	e.	e.	PROPN
bionys-641	412	97	,	,	PUNCT
bionys-641	412	98	amin	amin	PROPN
bionys-641	412	99	,	,	PUNCT
bionys-641	412	100	a	a	PRON
bionys-641	412	101	,	,	PUNCT
bionys-641	412	102	salman	salman	PROPN
bionys-641	412	103	ashraf	ashraf	PROPN
bionys-641	412	104	,	,	PUNCT
bionys-641	412	105	s.	s.	PROPN
bionys-641	412	106	,	,	PUNCT
bionys-641	412	107	boosani	boosani	PROPN
bionys-641	412	108	,	,	PUNCT
bionys-641	412	109	c.s	c.s	PROPN
bionys-641	412	110	.	.	PROPN
bionys-641	412	111	,	,	PUNCT
bionys-641	412	112	guha	guha	PROPN
bionys-641	412	113	,	,	PUNCT
bionys-641	412	114	g.	g.	PROPN
bionys-641	412	115	,	,	PUNCT
bionys-641	412	116	rosa	rosa	PROPN
bionys-641	412	117	ciriolo	ciriolo	PROPN
bionys-641	412	118	,	,	PUNCT
bionys-641	412	119	m.	m.	NOUN
bionys-641	412	120	,	,	PUNCT
bionys-641	412	121	aquilano	aquilano	PROPN
bionys-641	412	122	,	,	PUNCT
bionys-641	412	123	k.	k.	PROPN
bionys-641	412	124	,	,	PUNCT
bionys-641	412	125	chen	chen	PROPN
bionys-641	412	126	,	,	PUNCT
bionys-641	412	127	s.	s.	PROPN
bionys-641	412	128	,	,	PUNCT
bionys-641	412	129	mohammed	mohammed	PROPN
bionys-641	412	130	,	,	PUNCT
bionys-641	412	131	s.i	s.i	PROPN
bionys-641	412	132	.	.	PROPN
bionys-641	412	133	,	,	PUNCT
bionys-641	412	134	azmi	azmi	PROPN
bionys-641	412	135	,	,	PUNCT
bionys-641	412	136	a.s	a.s	PROPN
bionys-641	412	137	.	.	PROPN
bionys-641	412	138	,	,	PUNCT
bionys-641	412	139	bhakta	bhakta	NOUN
bionys-641	412	140	,	,	PUNCT
bionys-641	412	141	d.	d.	PROPN
bionys-641	412	142	,	,	PUNCT
bionys-641	412	143	halicka	halicka	PROPN
bionys-641	412	144	,	,	PUNCT
bionys-641	412	145	d.	d.	PROPN
bionys-641	412	146	,	,	PUNCT
bionys-641	412	147	nicol	nicol	PROPN
bionys-641	412	148	keith	keith	PROPN
bionys-641	412	149	,	,	PUNCT
bionys-641	412	150	w.	w.	PROPN
bionys-641	412	151	,	,	PUNCT
bionys-641	412	152	&	&	CCONJ
bionys-641	412	153	nowsheen	nowsheen	PROPN
bionys-641	412	154	,	,	PUNCT
bionys-641	412	155	s.	s.	PROPN
bionys-641	412	156	(	(	PUNCT
bionys-641	412	157	2015	2015	NUM
bionys-641	412	158	)	)	PUNCT
bionys-641	412	159	.	.	PUNCT
bionys-641	413	1	sustained	sustained	ADJ
bionys-641	413	2	proliferation	proliferation	NOUN
bionys-641	413	3	in	in	ADP
bionys-641	413	4	cancer	cancer	NOUN
bionys-641	413	5	:	:	PUNCT
bionys-641	413	6	mechanisms	mechanism	NOUN
bionys-641	413	7	and	and	CCONJ
bionys-641	413	8	novel	novel	ADJ
bionys-641	413	9	therapeutic	therapeutic	ADJ
bionys-641	413	10	targets	target	NOUN
bionys-641	413	11	.	.	PUNCT
bionys-641	414	1	seminars	seminar	NOUN
bionys-641	414	2	in	in	ADP
bionys-641	414	3	cancer	cancer	NOUN
bionys-641	414	4	biology	biology	NOUN
bionys-641	414	5	,	,	PUNCT
bionys-641	414	6	35	35	NUM
bionys-641	414	7	,	,	PUNCT
bionys-641	414	8	s25	s25	PROPN
bionys-641	414	9	–	–	PUNCT
bionys-641	414	10	s54	s54	PROPN
bionys-641	414	11	.	.	PUNCT
bionys-641	415	1	https://	https://	PROPN
bionys-641	415	2	doi.org/10.1016/j.semcancer.2015.02.006	doi.org/10.1016/j.semcancer.2015.02.006	NOUN
bionys-641	415	3	fernández	fernández	NOUN
bionys-641	415	4	-	-	PUNCT
bionys-641	415	5	lázaro	lázaro	NOUN
bionys-641	415	6	,	,	PUNCT
bionys-641	415	7	d.	d.	PROPN
bionys-641	415	8	,	,	PUNCT
bionys-641	415	9	sanz	sanz	PROPN
bionys-641	415	10	,	,	PUNCT
bionys-641	415	11	b.	b.	PROPN
bionys-641	415	12	,	,	PUNCT
bionys-641	415	13	&	&	CCONJ
bionys-641	415	14	seco	seco	PROPN
bionys-641	415	15	-	-	PROPN
bionys-641	415	16	calvo	calvo	PROPN
bionys-641	415	17	,	,	PUNCT
bionys-641	415	18	j.	j.	PROPN
bionys-641	415	19	(	(	PUNCT
bionys-641	415	20	2024	2024	NUM
bionys-641	415	21	)	)	PUNCT
bionys-641	415	22	.	.	PUNCT
bionys-641	416	1	the	the	DET
bionys-641	416	2	mechanisms	mechanism	NOUN
bionys-641	416	3	of	of	ADP
bionys-641	416	4	regulated	regulated	ADJ
bionys-641	416	5	cell	cell	NOUN
bionys-641	416	6	death	death	NOUN
bionys-641	416	7	:	:	PUNCT
bionys-641	416	8	structural	structural	ADJ
bionys-641	416	9	and	and	CCONJ
bionys-641	416	10	functional	functional	ADJ
bionys-641	416	11	proteomic	proteomic	ADJ
bionys-641	416	12	pathways	pathway	NOUN
bionys-641	416	13	induced	induce	VERB
bionys-641	416	14	or	or	CCONJ
bionys-641	416	15	inhibited	inhibit	VERB
bionys-641	416	16	by	by	ADP
bionys-641	416	17	a	a	DET
bionys-641	416	18	specific	specific	ADJ
bionys-641	416	19	protein	protein	NOUN
bionys-641	416	20	—	—	PUNCT
bionys-641	416	21	a	a	DET
bionys-641	416	22	narrative	narrative	NOUN
bionys-641	416	23	review	review	NOUN
bionys-641	416	24	.	.	PUNCT
bionys-641	417	1	proteomes	proteome	NOUN
bionys-641	417	2	,	,	PUNCT
bionys-641	417	3	12(1	12(1	NUM
bionys-641	417	4	)	)	PUNCT
bionys-641	417	5	,	,	PUNCT
bionys-641	417	6	3	3	X
bionys-641	417	7	.	.	PUNCT
bionys-641	418	1	https://doi	https://doi	NOUN
bionys-641	418	2	.	.	PUNCT
bionys-641	418	3	org/10.3390	org/10.3390	PROPN
bionys-641	418	4	/	/	SYM
bionys-641	418	5	proteomes12010003	proteomes12010003	PROPN
bionys-641	418	6	fink	fink	NOUN
bionys-641	418	7	,	,	PUNCT
bionys-641	418	8	s.l	s.l	PROPN
bionys-641	418	9	.	.	PROPN
bionys-641	418	10	,	,	PUNCT
bionys-641	418	11	&	&	CCONJ
bionys-641	418	12	cookson	cookson	PROPN
bionys-641	418	13	,	,	PUNCT
bionys-641	418	14	b.t	b.t	PROPN
bionys-641	418	15	.	.	PROPN
bionys-641	418	16	(	(	PUNCT
bionys-641	418	17	2005	2005	NUM
bionys-641	418	18	)	)	PUNCT
bionys-641	418	19	.	.	PUNCT
bionys-641	419	1	apoptosis	apoptosis	NOUN
bionys-641	419	2	,	,	PUNCT
bionys-641	419	3	pyroptosis	pyroptosis	NOUN
bionys-641	419	4	,	,	PUNCT
bionys-641	419	5	and	and	CCONJ
bionys-641	419	6	necrosis	necrosis	NOUN
bionys-641	419	7	:	:	PUNCT
bionys-641	419	8	mechanistic	mechanistic	ADJ
bionys-641	419	9	description	description	NOUN
bionys-641	419	10	of	of	ADP
bionys-641	419	11	dead	dead	ADJ
bionys-641	419	12	and	and	CCONJ
bionys-641	419	13	dying	die	VERB
bionys-641	419	14	eukaryotic	eukaryotic	ADJ
bionys-641	419	15	cells	cell	NOUN
bionys-641	419	16	.	.	PUNCT
bionys-641	420	1	infection	infection	NOUN
bionys-641	420	2	and	and	CCONJ
bionys-641	420	3	immunity	immunity	NOUN
bionys-641	420	4	,	,	PUNCT
bionys-641	420	5	73(4	73(4	NOUN
bionys-641	420	6	)	)	PUNCT
bionys-641	420	7	,	,	PUNCT
bionys-641	420	8	1907–1916	1907–1916	NUM
bionys-641	420	9	.	.	PUNCT
bionys-641	421	1	https://doi	https://doi	PROPN
bionys-641	421	2	.	.	PUNCT
bionys-641	421	3	org/10.1128	org/10.1128	PROPN
bionys-641	421	4	/	/	SYM
bionys-641	421	5	iai.73.4.1907	iai.73.4.1907	PROPN
bionys-641	421	6	-	-	PUNCT
bionys-641	421	7	1916.2005	1916.2005	NUM
bionys-641	421	8	fogde	fogde	NOUN
bionys-641	421	9	,	,	PUNCT
bionys-641	421	10	d.l	d.l	PROPN
bionys-641	421	11	.	.	PROPN
bionys-641	421	12	,	,	PUNCT
bionys-641	421	13	xavier	xavier	PROPN
bionys-641	421	14	,	,	PUNCT
bionys-641	421	15	c.p.r	c.p.r	NOUN
bionys-641	421	16	.	.	PUNCT
bionys-641	421	17	,	,	PUNCT
bionys-641	421	18	balnytė	balnytė	NOUN
bionys-641	421	19	,	,	PUNCT
bionys-641	421	20	k.	k.	PROPN
bionys-641	421	21	,	,	PUNCT
bionys-641	421	22	holland	holland	PROPN
bionys-641	421	23	,	,	PUNCT
bionys-641	421	24	l.k.k	l.k.k	PROPN
bionys-641	421	25	.	.	PROPN
bionys-641	421	26	,	,	PUNCT
bionys-641	421	27	stahl	stahl	PROPN
bionys-641	421	28	-	-	PUNCT
bionys-641	421	29	meyer	meyer	PROPN
bionys-641	421	30	,	,	PUNCT
bionys-641	421	31	k.	k.	PROPN
bionys-641	421	32	,	,	PUNCT
bionys-641	421	33	dinant	dinant	NOUN
bionys-641	421	34	,	,	PUNCT
bionys-641	421	35	c.	c.	PROPN
bionys-641	421	36	,	,	PUNCT
bionys-641	421	37	corcelletermeau	corcelletermeau	PROPN
bionys-641	421	38	,	,	PUNCT
bionys-641	421	39	e.	e.	PROPN
bionys-641	421	40	,	,	PUNCT
bionys-641	421	41	pereira	pereira	PROPN
bionys-641	421	42	-	-	PUNCT
bionys-641	421	43	wilson	wilson	PROPN
bionys-641	421	44	,	,	PUNCT
bionys-641	421	45	c.	c.	PROPN
bionys-641	421	46	,	,	PUNCT
bionys-641	421	47	maeda	maeda	PROPN
bionys-641	421	48	,	,	PUNCT
bionys-641	421	49	k.	k.	PROPN
bionys-641	421	50	,	,	PUNCT
bionys-641	421	51	&	&	CCONJ
bionys-641	421	52	jäättelä	jäättelä	PROPN
bionys-641	421	53	,	,	PUNCT
bionys-641	421	54	m.	m.	NOUN
bionys-641	421	55	(	(	PUNCT
bionys-641	421	56	2022	2022	NUM
bionys-641	421	57	)	)	PUNCT
bionys-641	421	58	.	.	PUNCT
bionys-641	422	1	ursolic	ursolic	ADJ
bionys-641	422	2	acid	acid	PROPN
bionys-641	422	3	impairs	impair	VERB
bionys-641	422	4	cellular	cellular	ADJ
bionys-641	422	5	lipid	lipid	NOUN
bionys-641	422	6	homeostasis	homeostasis	NOUN
bionys-641	422	7	and	and	CCONJ
bionys-641	422	8	lysosomal	lysosomal	ADJ
bionys-641	422	9	membrane	membrane	NOUN
bionys-641	422	10	integrity	integrity	NOUN
bionys-641	422	11	in	in	ADP
bionys-641	422	12	breast	breast	NOUN
bionys-641	422	13	carcinoma	carcinoma	NOUN
bionys-641	422	14	cells	cell	NOUN
bionys-641	422	15	.	.	PUNCT
bionys-641	423	1	cells	cell	NOUN
bionys-641	423	2	,	,	PUNCT
bionys-641	423	3	11(24	11(24	NUM
bionys-641	423	4	)	)	PUNCT
bionys-641	423	5	,	,	PUNCT
bionys-641	423	6	4079	4079	NUM
bionys-641	423	7	.	.	PUNCT
bionys-641	424	1	https://doi.org/10.3390/cells11244079	https://doi.org/10.3390/cells11244079	PROPN
bionys-641	424	2	fossati	fossati	PROPN
bionys-641	424	3	,	,	PUNCT
bionys-641	424	4	s.	s.	PROPN
bionys-641	424	5	,	,	PUNCT
bionys-641	424	6	ghiso	ghiso	PROPN
bionys-641	424	7	,	,	PUNCT
bionys-641	424	8	j.	j.	PROPN
bionys-641	424	9	,	,	PUNCT
bionys-641	424	10	&	&	CCONJ
bionys-641	424	11	rostagno	rostagno	NOUN
bionys-641	424	12	,	,	PUNCT
bionys-641	424	13	a.	a.	NOUN
bionys-641	424	14	(	(	PUNCT
bionys-641	424	15	2012	2012	NUM
bionys-641	424	16	)	)	PUNCT
bionys-641	424	17	.	.	PUNCT
bionys-641	425	1	trail	trail	NOUN
bionys-641	425	2	death	death	NOUN
bionys-641	425	3	receptors	receptor	NOUN
bionys-641	425	4	dr4	dr4	NOUN
bionys-641	425	5	and	and	CCONJ
bionys-641	425	6	dr5	dr5	PROPN
bionys-641	425	7	mediate	mediate	PROPN
bionys-641	425	8	cerebral	cerebral	ADJ
bionys-641	425	9	microvascular	microvascular	ADJ
bionys-641	425	10	endothelial	endothelial	ADJ
bionys-641	425	11	cell	cell	NOUN
bionys-641	425	12	apoptosis	apoptosis	NOUN
bionys-641	425	13	induced	induce	VERB
bionys-641	425	14	by	by	ADP
bionys-641	425	15	oligomeric	oligomeric	ADJ
bionys-641	425	16	alzheimer	alzheimer	PROPN
bionys-641	425	17	’s	’s	PART
bionys-641	425	18	aβ	aβ	PROPN
bionys-641	425	19	.	.	PROPN
bionys-641	425	20	cell	cell	NOUN
bionys-641	425	21	death	death	NOUN
bionys-641	425	22	&	&	CCONJ
bionys-641	425	23	disease	disease	PROPN
bionys-641	425	24	,	,	PUNCT
bionys-641	425	25	3(6	3(6	NUM
bionys-641	425	26	)	)	PUNCT
bionys-641	425	27	,	,	PUNCT
bionys-641	425	28	e321	e321	PROPN
bionys-641	425	29	.	.	PUNCT
bionys-641	425	30	https://doi.org/10.1038/	https://doi.org/10.1038/	PROPN
bionys-641	425	31	cddis.2012.55	cddis.2012.55	NOUN
bionys-641	425	32	fulda	fulda	NOUN
bionys-641	425	33	,	,	PUNCT
bionys-641	425	34	s.	s.	PROPN
bionys-641	425	35	(	(	PUNCT
bionys-641	425	36	2015	2015	NUM
bionys-641	425	37	)	)	PUNCT
bionys-641	425	38	.	.	PUNCT
bionys-641	426	1	targeting	target	VERB
bionys-641	426	2	apoptosis	apoptosis	NOUN
bionys-641	426	3	for	for	ADP
bionys-641	426	4	anticancer	anticancer	NOUN
bionys-641	426	5	therapy	therapy	NOUN
bionys-641	426	6	.	.	PUNCT
bionys-641	427	1	seminars	seminar	NOUN
bionys-641	427	2	in	in	ADP
bionys-641	427	3	cancer	cancer	NOUN
bionys-641	427	4	biology	biology	NOUN
bionys-641	427	5	,	,	PUNCT
bionys-641	427	6	31	31	NUM
bionys-641	427	7	,	,	PUNCT
bionys-641	427	8	84–88	84–88	NUM
bionys-641	427	9	.	.	PUNCT
bionys-641	428	1	https://doi.org/10.1016/j.semcancer.2014.05.002	https://doi.org/10.1016/j.semcancer.2014.05.002	NOUN
bionys-641	428	2	galluzzi	galluzzi	NOUN
bionys-641	428	3	,	,	PUNCT
bionys-641	428	4	l.	l.	PROPN
bionys-641	428	5	,	,	PUNCT
bionys-641	428	6	vitale	vitale	PROPN
bionys-641	428	7	,	,	PUNCT
bionys-641	428	8	i.	i.	PROPN
bionys-641	428	9	,	,	PUNCT
bionys-641	428	10	aaronson	aaronson	PROPN
bionys-641	428	11	,	,	PUNCT
bionys-641	428	12	s.a	s.a	PROPN
bionys-641	428	13	.	.	PROPN
bionys-641	428	14	,	,	PUNCT
bionys-641	428	15	abrams	abrams	PROPN
bionys-641	428	16	,	,	PUNCT
bionys-641	428	17	j.m	j.m	PROPN
bionys-641	428	18	.	.	PROPN
bionys-641	428	19	,	,	PUNCT
bionys-641	428	20	adam	adam	PROPN
bionys-641	428	21	,	,	PUNCT
bionys-641	428	22	d.	d.	PROPN
bionys-641	428	23	,	,	PUNCT
bionys-641	428	24	agostinis	agostinis	PROPN
bionys-641	428	25	,	,	PUNCT
bionys-641	428	26	p.	p.	NOUN
bionys-641	428	27	,	,	PUNCT
bionys-641	428	28	alnemri	alnemri	PROPN
bionys-641	428	29	,	,	PUNCT
bionys-641	428	30	e.s	e.s	PROPN
bionys-641	428	31	.	.	PROPN
bionys-641	428	32	,	,	PUNCT
bionys-641	428	33	altucci	altucci	PROPN
bionys-641	428	34	,	,	PUNCT
bionys-641	428	35	l.	l.	PROPN
bionys-641	428	36	,	,	PUNCT
bionys-641	428	37	amelio	amelio	PROPN
bionys-641	428	38	,	,	PUNCT
bionys-641	428	39	i.	i.	PROPN
bionys-641	428	40	,	,	PUNCT
bionys-641	428	41	andrews	andrews	PROPN
bionys-641	428	42	,	,	PUNCT
bionys-641	428	43	d.w	d.w	PROPN
bionys-641	428	44	.	.	PROPN
bionys-641	428	45	,	,	PUNCT
bionys-641	428	46	annicchiarico	annicchiarico	NOUN
bionys-641	428	47	-	-	PUNCT
bionys-641	428	48	petruzzelli	petruzzelli	NOUN
bionys-641	428	49	,	,	PUNCT
bionys-641	428	50	m.	m.	NOUN
bionys-641	428	51	,	,	PUNCT
bionys-641	428	52	antonov	antonov	PROPN
bionys-641	428	53	,	,	PUNCT
bionys-641	428	54	a.v	a.v	PROPN
bionys-641	428	55	,	,	PUNCT
bionys-641	428	56	arama	arama	PROPN
bionys-641	428	57	,	,	PUNCT
bionys-641	428	58	e.	e.	PROPN
bionys-641	428	59	,	,	PUNCT
bionys-641	428	60	baehrecke	baehrecke	PROPN
bionys-641	428	61	,	,	PUNCT
bionys-641	428	62	e.h	e.h	PROPN
bionys-641	428	63	.	.	PROPN
bionys-641	428	64	,	,	PUNCT
bionys-641	428	65	barlev	barlev	NOUN
bionys-641	428	66	,	,	PUNCT
bionys-641	428	67	n.a	n.a	PROPN
bionys-641	428	68	.	.	PROPN
bionys-641	428	69	,	,	PUNCT
bionys-641	428	70	bazan	bazan	PROPN
bionys-641	428	71	,	,	PUNCT
bionys-641	428	72	n.g	n.g	PROPN
bionys-641	428	73	.	.	PROPN
bionys-641	428	74	,	,	PUNCT
bionys-641	428	75	bernassola	bernassola	PROPN
bionys-641	428	76	,	,	PUNCT
bionys-641	428	77	f.	f.	PROPN
bionys-641	428	78	,	,	PUNCT
bionys-641	428	79	bertrand	bertrand	PROPN
bionys-641	428	80	,	,	PUNCT
bionys-641	428	81	m.j.m	m.j.m	PROPN
bionys-641	428	82	.	.	PROPN
bionys-641	428	83	,	,	PUNCT
bionys-641	428	84	bianchi	bianchi	PROPN
bionys-641	428	85	,	,	PUNCT
bionys-641	428	86	k.	k.	PROPN
bionys-641	428	87	,	,	PUNCT
bionys-641	428	88	…	…	PUNCT
bionys-641	428	89	kroemer	kroemer	PROPN
bionys-641	428	90	,	,	PUNCT
bionys-641	428	91	g.	g.	PROPN
bionys-641	428	92	(	(	PUNCT
bionys-641	428	93	2018	2018	NUM
bionys-641	428	94	)	)	PUNCT
bionys-641	428	95	.	.	PUNCT
bionys-641	429	1	molecular	molecular	ADJ
bionys-641	429	2	mechanisms	mechanism	NOUN
bionys-641	429	3	of	of	ADP
bionys-641	429	4	cell	cell	NOUN
bionys-641	429	5	death	death	NOUN
bionys-641	429	6	:	:	PUNCT
bionys-641	429	7	recommendations	recommendation	NOUN
bionys-641	429	8	of	of	ADP
bionys-641	429	9	the	the	DET
bionys-641	429	10	nomenclature	nomenclature	NOUN
bionys-641	429	11	committee	committee	NOUN
bionys-641	429	12	on	on	ADP
bionys-641	429	13	cell	cell	NOUN
bionys-641	429	14	death	death	NOUN
bionys-641	429	15	2018	2018	NUM
bionys-641	429	16	.	.	PUNCT
bionys-641	430	1	cell	cell	NOUN
bionys-641	430	2	death	death	NOUN
bionys-641	430	3	and	and	CCONJ
bionys-641	430	4	differentiation	differentiation	NOUN
bionys-641	430	5	,	,	PUNCT
bionys-641	430	6	25(3	25(3	NUM
bionys-641	430	7	)	)	PUNCT
bionys-641	430	8	,	,	PUNCT
bionys-641	430	9	486–541	486–541	NUM
bionys-641	430	10	.	.	PUNCT
bionys-641	431	1	https://	https://	PROPN
bionys-641	431	2	doi.org/10.1038/s41418-017-0012-4	doi.org/10.1038/s41418-017-0012-4	VERB
bionys-641	431	3	biologica	biologica	ADJ
bionys-641	431	4	nyssana	nyssana	PROPN
bionys-641	432	1	●	●	PUNCT
bionys-641	432	2	16	16	NUM
bionys-641	432	3	(	(	PUNCT
bionys-641	432	4	2	2	NUM
bionys-641	432	5	)	)	PUNCT
bionys-641	432	6	december	december	PROPN
bionys-641	432	7	2025	2025	NUM
bionys-641	432	8	:	:	PUNCT
bionys-641	432	9	liana	liana	NOUN
bionys-641	432	10	et	et	PROPN
bionys-641	432	11	al	al	PROPN
bionys-641	432	12	.	.	PUNCT
bionys-641	433	1	●	●	PUNCT
bionys-641	433	2	cell	cell	NOUN
bionys-641	433	3	deaths	death	NOUN
bionys-641	433	4	and	and	CCONJ
bionys-641	433	5	their	their	PRON
bionys-641	433	6	associated	associate	VERB
bionys-641	433	7	mechanisms	mechanism	NOUN
bionys-641	433	8	galluzzi	galluzzi	VERB
bionys-641	433	9	,	,	PUNCT
bionys-641	433	10	l.	l.	PROPN
bionys-641	433	11	,	,	PUNCT
bionys-641	433	12	vitale	vitale	PROPN
bionys-641	433	13	,	,	PUNCT
bionys-641	433	14	i.	i.	PROPN
bionys-641	433	15	,	,	PUNCT
bionys-641	433	16	warren	warren	PROPN
bionys-641	433	17	,	,	PUNCT
bionys-641	433	18	s.	s.	PROPN
bionys-641	433	19	,	,	PUNCT
bionys-641	433	20	adjemian	adjemian	PROPN
bionys-641	433	21	,	,	PUNCT
bionys-641	433	22	s.	s.	PROPN
bionys-641	433	23	,	,	PUNCT
bionys-641	433	24	agostinis	agostinis	PROPN
bionys-641	433	25	,	,	PUNCT
bionys-641	433	26	p.	p.	PROPN
bionys-641	433	27	,	,	PUNCT
bionys-641	433	28	martinez	martinez	PROPN
bionys-641	433	29	,	,	PUNCT
bionys-641	433	30	a.b	a.b	PROPN
bionys-641	433	31	.	.	PROPN
bionys-641	433	32	,	,	PUNCT
bionys-641	433	33	chan	chan	PROPN
bionys-641	433	34	,	,	PUNCT
bionys-641	433	35	t.	t.	PROPN
bionys-641	433	36	a.	a.	NOUN
bionys-641	433	37	,	,	PUNCT
bionys-641	433	38	coukos	coukos	NOUN
bionys-641	433	39	,	,	PUNCT
bionys-641	433	40	g.	g.	PROPN
bionys-641	433	41	,	,	PUNCT
bionys-641	433	42	demaria	demaria	PROPN
bionys-641	433	43	,	,	PUNCT
bionys-641	433	44	s.	s.	PROPN
bionys-641	433	45	,	,	PUNCT
bionys-641	433	46	deutsch	deutsch	PROPN
bionys-641	433	47	,	,	PUNCT
bionys-641	433	48	e.	e.	PROPN
bionys-641	433	49	,	,	PUNCT
bionys-641	433	50	draganov	draganov	PROPN
bionys-641	433	51	,	,	PUNCT
bionys-641	433	52	d.	d.	PROPN
bionys-641	433	53	,	,	PUNCT
bionys-641	433	54	edelson	edelson	PROPN
bionys-641	433	55	,	,	PUNCT
bionys-641	433	56	r.l	r.l	PROPN
bionys-641	433	57	.	.	PROPN
bionys-641	433	58	,	,	PUNCT
bionys-641	433	59	formenti	formenti	PROPN
bionys-641	433	60	,	,	PUNCT
bionys-641	433	61	s.	s.	PROPN
bionys-641	433	62	c.	c.	PROPN
bionys-641	433	63	,	,	PUNCT
bionys-641	433	64	fucikova	fucikova	PROPN
bionys-641	433	65	,	,	PUNCT
bionys-641	433	66	j.	j.	PROPN
bionys-641	433	67	,	,	PUNCT
bionys-641	433	68	gabriele	gabriele	PROPN
bionys-641	433	69	,	,	PUNCT
bionys-641	433	70	l.	l.	PROPN
bionys-641	433	71	,	,	PUNCT
bionys-641	433	72	gaipl	gaipl	PROPN
bionys-641	433	73	,	,	PUNCT
bionys-641	433	74	u.s	u.s	PROPN
bionys-641	433	75	.	.	PROPN
bionys-641	433	76	,	,	PUNCT
bionys-641	433	77	gameiro	gameiro	PROPN
bionys-641	433	78	,	,	PUNCT
bionys-641	433	79	s.r	s.r	PROPN
bionys-641	433	80	.	.	PROPN
bionys-641	433	81	,	,	PUNCT
bionys-641	433	82	garg	garg	PROPN
bionys-641	433	83	,	,	PUNCT
bionys-641	433	84	a.d	a.d	PROPN
bionys-641	433	85	.	.	PROPN
bionys-641	433	86	,	,	PUNCT
bionys-641	433	87	golden	golden	PROPN
bionys-641	433	88	,	,	PUNCT
bionys-641	433	89	e.	e.	PROPN
bionys-641	433	90	,	,	PUNCT
bionys-641	433	91	…	…	PUNCT
bionys-641	433	92	marincola	marincola	NOUN
bionys-641	433	93	,	,	PUNCT
bionys-641	433	94	f.m	f.m	PROPN
bionys-641	433	95	.	.	PROPN
bionys-641	433	96	(	(	PUNCT
bionys-641	433	97	2020	2020	NUM
bionys-641	433	98	)	)	PUNCT
bionys-641	433	99	.	.	PUNCT
bionys-641	434	1	consensus	consensus	NOUN
bionys-641	434	2	guidelines	guideline	NOUN
bionys-641	434	3	for	for	ADP
bionys-641	434	4	the	the	DET
bionys-641	434	5	definition	definition	NOUN
bionys-641	434	6	,	,	PUNCT
bionys-641	434	7	detection	detection	NOUN
bionys-641	434	8	and	and	CCONJ
bionys-641	434	9	interpretation	interpretation	NOUN
bionys-641	434	10	of	of	ADP
bionys-641	434	11	immunogenic	immunogenic	ADJ
bionys-641	434	12	cell	cell	NOUN
bionys-641	434	13	death	death	NOUN
bionys-641	434	14	.	.	PUNCT
bionys-641	435	1	journal	journal	PROPN
bionys-641	435	2	for	for	ADP
bionys-641	435	3	immunotherapy	immunotherapy	NOUN
bionys-641	435	4	of	of	ADP
bionys-641	435	5	cancer	cancer	NOUN
bionys-641	435	6	,	,	PUNCT
bionys-641	435	7	8(1	8(1	NOUN
bionys-641	435	8	)	)	PUNCT
bionys-641	435	9	,	,	PUNCT
bionys-641	435	10	e000337	e000337	PROPN
bionys-641	435	11	.	.	PUNCT
bionys-641	436	1	https://doi.org/10.1136/jitc-2019-000337	https://doi.org/10.1136/jitc-2019-000337	PROPN
bionys-641	436	2	ghoochani	ghoochani	PROPN
bionys-641	436	3	,	,	PUNCT
bionys-641	436	4	a.	a.	PROPN
bionys-641	436	5	,	,	PUNCT
bionys-641	436	6	hsu	hsu	PROPN
bionys-641	436	7	,	,	PUNCT
bionys-641	436	8	e.-c	e.-c	NOUN
bionys-641	436	9	.	.	PUNCT
bionys-641	436	10	,	,	PUNCT
bionys-641	436	11	aslan	aslan	PROPN
bionys-641	436	12	,	,	PUNCT
bionys-641	436	13	m.	m.	NOUN
bionys-641	436	14	,	,	PUNCT
bionys-641	436	15	rice	rice	NOUN
bionys-641	436	16	,	,	PUNCT
bionys-641	436	17	m.a	m.a	PROPN
bionys-641	436	18	.	.	PROPN
bionys-641	436	19	,	,	PUNCT
bionys-641	436	20	nguyen	nguyen	PROPN
bionys-641	436	21	,	,	PUNCT
bionys-641	436	22	h.m	h.m	PROPN
bionys-641	436	23	.	.	PROPN
bionys-641	436	24	,	,	PUNCT
bionys-641	436	25	brooks	brooks	PROPN
bionys-641	436	26	,	,	PUNCT
bionys-641	436	27	j.d	j.d	PROPN
bionys-641	436	28	.	.	PROPN
bionys-641	436	29	,	,	PUNCT
bionys-641	436	30	corey	corey	PROPN
bionys-641	436	31	,	,	PUNCT
bionys-641	436	32	e.	e.	PROPN
bionys-641	436	33	,	,	PUNCT
bionys-641	436	34	paulmurugan	paulmurugan	VERB
bionys-641	436	35	,	,	PUNCT
bionys-641	436	36	r.	r.	PROPN
bionys-641	436	37	,	,	PUNCT
bionys-641	436	38	&	&	CCONJ
bionys-641	436	39	stoyanova	stoyanova	PROPN
bionys-641	436	40	,	,	PUNCT
bionys-641	436	41	t.	t.	PROPN
bionys-641	436	42	(	(	PUNCT
bionys-641	436	43	2021	2021	NUM
bionys-641	436	44	)	)	PUNCT
bionys-641	436	45	.	.	PUNCT
bionys-641	437	1	ferroptosis	ferroptosis	NOUN
bionys-641	437	2	inducers	inducer	NOUN
bionys-641	437	3	are	be	AUX
bionys-641	437	4	a	a	DET
bionys-641	437	5	novel	novel	ADJ
bionys-641	437	6	therapeutic	therapeutic	ADJ
bionys-641	437	7	approach	approach	NOUN
bionys-641	437	8	for	for	ADP
bionys-641	437	9	advanced	advanced	ADJ
bionys-641	437	10	prostate	prostate	NOUN
bionys-641	437	11	cancer	cancer	NOUN
bionys-641	437	12	.	.	PUNCT
bionys-641	438	1	cancer	cancer	NOUN
bionys-641	438	2	research	research	NOUN
bionys-641	438	3	,	,	PUNCT
bionys-641	438	4	81(6	81(6	NUM
bionys-641	438	5	)	)	PUNCT
bionys-641	438	6	,	,	PUNCT
bionys-641	438	7	1583–1594	1583–1594	NUM
bionys-641	438	8	.	.	PUNCT
bionys-641	439	1	https://doi	https://doi	PROPN
bionys-641	439	2	.	.	PUNCT
bionys-641	439	3	org/10.1158/0008	org/10.1158/0008	NOUN
bionys-641	439	4	-	-	PUNCT
bionys-641	439	5	5472.can-20	5472.can-20	NUM
bionys-641	439	6	-	-	PUNCT
bionys-641	439	7	3477	3477	NUM
bionys-641	439	8	giannoni	giannoni	NOUN
bionys-641	439	9	,	,	PUNCT
bionys-641	439	10	e.	e.	PROPN
bionys-641	439	11	,	,	PUNCT
bionys-641	439	12	buricchi	buricchi	PROPN
bionys-641	439	13	,	,	PUNCT
bionys-641	439	14	f.	f.	PROPN
bionys-641	439	15	,	,	PUNCT
bionys-641	439	16	grimaldi	grimaldi	PROPN
bionys-641	439	17	,	,	PUNCT
bionys-641	439	18	g.	g.	PROPN
bionys-641	439	19	,	,	PUNCT
bionys-641	439	20	parri	parri	NOUN
bionys-641	439	21	,	,	PUNCT
bionys-641	439	22	m.	m.	NOUN
bionys-641	439	23	,	,	PUNCT
bionys-641	439	24	cialdai	cialdai	PROPN
bionys-641	439	25	,	,	PUNCT
bionys-641	439	26	f.	f.	PROPN
bionys-641	439	27	,	,	PUNCT
bionys-641	439	28	taddei	taddei	PROPN
bionys-641	439	29	,	,	PUNCT
bionys-641	439	30	m.l	m.l	PROPN
bionys-641	439	31	.	.	PROPN
bionys-641	439	32	,	,	PUNCT
bionys-641	439	33	raugei	raugei	NOUN
bionys-641	439	34	,	,	PUNCT
bionys-641	439	35	g.	g.	PROPN
bionys-641	439	36	,	,	PUNCT
bionys-641	439	37	ramponi	ramponi	NOUN
bionys-641	439	38	,	,	PUNCT
bionys-641	439	39	g.	g.	PROPN
bionys-641	439	40	,	,	PUNCT
bionys-641	439	41	&	&	CCONJ
bionys-641	439	42	chiarugi	chiarugi	PROPN
bionys-641	439	43	,	,	PUNCT
bionys-641	439	44	p.	p.	NOUN
bionys-641	439	45	(	(	PUNCT
bionys-641	439	46	2008	2008	NUM
bionys-641	439	47	)	)	PUNCT
bionys-641	439	48	.	.	PUNCT
bionys-641	440	1	redox	redox	ADJ
bionys-641	440	2	regulation	regulation	NOUN
bionys-641	440	3	of	of	ADP
bionys-641	440	4	anoikis	anoiki	NOUN
bionys-641	440	5	:	:	PUNCT
bionys-641	440	6	reactive	reactive	ADJ
bionys-641	440	7	oxygen	oxygen	NOUN
bionys-641	440	8	species	specie	NOUN
bionys-641	440	9	as	as	ADP
bionys-641	440	10	essential	essential	ADJ
bionys-641	440	11	mediators	mediator	NOUN
bionys-641	440	12	of	of	ADP
bionys-641	440	13	cell	cell	NOUN
bionys-641	440	14	survival	survival	NOUN
bionys-641	440	15	.	.	PUNCT
bionys-641	441	1	cell	cell	NOUN
bionys-641	441	2	death	death	NOUN
bionys-641	441	3	&	&	CCONJ
bionys-641	441	4	differentiation	differentiation	NOUN
bionys-641	441	5	,	,	PUNCT
bionys-641	441	6	15(5	15(5	NUM
bionys-641	441	7	)	)	PUNCT
bionys-641	441	8	,	,	PUNCT
bionys-641	441	9	867–878	867–878	NUM
bionys-641	441	10	.	.	PUNCT
bionys-641	442	1	https://doi	https://doi	PROPN
bionys-641	442	2	.	.	PUNCT
bionys-641	442	3	org/10.1038	org/10.1038	PROPN
bionys-641	442	4	/	/	SYM
bionys-641	442	5	cdd.2008.3	cdd.2008.3	PROPN
bionys-641	442	6	gonen	gonen	NOUN
bionys-641	442	7	,	,	PUNCT
bionys-641	442	8	o.m	o.m	PROPN
bionys-641	442	9	.	.	PROPN
bionys-641	442	10	,	,	PUNCT
bionys-641	442	11	porter	porter	NOUN
bionys-641	442	12	,	,	PUNCT
bionys-641	442	13	t.	t.	PROPN
bionys-641	442	14	,	,	PUNCT
bionys-641	442	15	wang	wang	PROPN
bionys-641	442	16	,	,	PUNCT
bionys-641	442	17	b.	b.	PROPN
bionys-641	442	18	,	,	PUNCT
bionys-641	442	19	xue	xue	PROPN
bionys-641	442	20	,	,	PUNCT
bionys-641	442	21	f.	f.	PROPN
bionys-641	442	22	,	,	PUNCT
bionys-641	442	23	ma	ma	PROPN
bionys-641	442	24	,	,	PUNCT
bionys-641	442	25	y.	y.	PROPN
bionys-641	442	26	,	,	PUNCT
bionys-641	442	27	song	song	NOUN
bionys-641	442	28	,	,	PUNCT
bionys-641	442	29	l.	l.	PROPN
bionys-641	442	30	,	,	PUNCT
bionys-641	442	31	sun	sun	PROPN
bionys-641	442	32	,	,	PUNCT
bionys-641	442	33	p.	p.	PROPN
bionys-641	442	34	,	,	PUNCT
bionys-641	442	35	fan	fan	PROPN
bionys-641	442	36	,	,	PUNCT
bionys-641	442	37	w.	w.	PROPN
bionys-641	442	38	,	,	PUNCT
bionys-641	442	39	&	&	CCONJ
bionys-641	442	40	shen	shen	PROPN
bionys-641	442	41	,	,	PUNCT
bionys-641	442	42	y.	y.	PROPN
bionys-641	442	43	(	(	PUNCT
bionys-641	442	44	2025	2025	NUM
bionys-641	442	45	)	)	PUNCT
bionys-641	442	46	.	.	PUNCT
bionys-641	443	1	safety	safety	NOUN
bionys-641	443	2	,	,	PUNCT
bionys-641	443	3	pharmacokinetics	pharmacokinetic	NOUN
bionys-641	443	4	and	and	CCONJ
bionys-641	443	5	target	target	NOUN
bionys-641	443	6	engagement	engagement	NOUN
bionys-641	443	7	of	of	ADP
bionys-641	443	8	a	a	DET
bionys-641	443	9	novel	novel	ADJ
bionys-641	443	10	brain	brain	NOUN
bionys-641	443	11	penetrant	penetrant	NOUN
bionys-641	443	12	ripk1	ripk1	NOUN
bionys-641	443	13	inhibitor	inhibitor	NOUN
bionys-641	443	14	(	(	PUNCT
bionys-641	443	15	sir9900	sir9900	ADJ
bionys-641	443	16	)	)	PUNCT
bionys-641	443	17	in	in	ADP
bionys-641	443	18	healthy	healthy	ADJ
bionys-641	443	19	adults	adult	NOUN
bionys-641	443	20	and	and	CCONJ
bionys-641	443	21	elderly	elderly	ADJ
bionys-641	443	22	participants	participant	NOUN
bionys-641	443	23	.	.	PUNCT
bionys-641	444	1	clinical	clinical	ADJ
bionys-641	444	2	and	and	CCONJ
bionys-641	444	3	translational	translational	ADJ
bionys-641	444	4	science	science	NOUN
bionys-641	444	5	,	,	PUNCT
bionys-641	444	6	18(2	18(2	NUM
bionys-641	444	7	)	)	PUNCT
bionys-641	444	8	,	,	PUNCT
bionys-641	444	9	e70151	e70151	PROPN
bionys-641	444	10	.	.	PUNCT
bionys-641	445	1	https://	https://	PROPN
bionys-641	445	2	doi.org/10.1111/cts.70151	doi.org/10.1111/cts.70151	PROPN
bionys-641	445	3	gorman	gorman	PROPN
bionys-641	445	4	,	,	PUNCT
bionys-641	445	5	a.m.	a.m.	PROPN
bionys-641	445	6	(	(	PUNCT
bionys-641	445	7	2008	2008	NUM
bionys-641	445	8	)	)	PUNCT
bionys-641	445	9	.	.	PUNCT
bionys-641	446	1	neuronal	neuronal	ADJ
bionys-641	446	2	cell	cell	NOUN
bionys-641	446	3	death	death	NOUN
bionys-641	446	4	in	in	ADP
bionys-641	446	5	neurodegenerative	neurodegenerative	ADJ
bionys-641	446	6	diseases	disease	NOUN
bionys-641	446	7	:	:	PUNCT
bionys-641	446	8	recurring	recur	VERB
bionys-641	446	9	themes	theme	NOUN
bionys-641	446	10	around	around	ADP
bionys-641	446	11	protein	protein	NOUN
bionys-641	446	12	handling	handling	NOUN
bionys-641	446	13	.	.	PUNCT
bionys-641	447	1	journal	journal	NOUN
bionys-641	447	2	of	of	ADP
bionys-641	447	3	cellular	cellular	ADJ
bionys-641	447	4	and	and	CCONJ
bionys-641	447	5	molecular	molecular	ADJ
bionys-641	447	6	medicine	medicine	NOUN
bionys-641	447	7	,	,	PUNCT
bionys-641	447	8	12(6a	12(6a	NUM
bionys-641	447	9	)	)	PUNCT
bionys-641	447	10	,	,	PUNCT
bionys-641	447	11	2263–2280	2263–2280	NUM
bionys-641	447	12	.	.	PUNCT
bionys-641	448	1	https://	https://	PROPN
bionys-641	448	2	doi.org/10.1111/j.1582-4934.2008.00402.x	doi.org/10.1111/j.1582-4934.2008.00402.x	PROPN
bionys-641	448	3	guhl	guhl	PROPN
bionys-641	448	4	,	,	PUNCT
bionys-641	448	5	s.	s.	PROPN
bionys-641	448	6	,	,	PUNCT
bionys-641	448	7	hartmann	hartmann	PROPN
bionys-641	448	8	,	,	PUNCT
bionys-641	448	9	k.	k.	PROPN
bionys-641	448	10	,	,	PUNCT
bionys-641	448	11	tapkenhinrichs	tapkenhinrichs	PROPN
bionys-641	448	12	,	,	PUNCT
bionys-641	448	13	s.	s.	PROPN
bionys-641	448	14	,	,	PUNCT
bionys-641	448	15	smorodchenko	smorodchenko	PROPN
bionys-641	448	16	,	,	PUNCT
bionys-641	448	17	a.	a.	NOUN
bionys-641	448	18	,	,	PUNCT
bionys-641	448	19	grützkau	grützkau	NOUN
bionys-641	448	20	,	,	PUNCT
bionys-641	448	21	a.	a.	NOUN
bionys-641	448	22	,	,	PUNCT
bionys-641	448	23	henz	henz	PROPN
bionys-641	448	24	,	,	PUNCT
bionys-641	448	25	b.m	b.m	PROPN
bionys-641	448	26	.	.	PROPN
bionys-641	448	27	,	,	PUNCT
bionys-641	448	28	&	&	CCONJ
bionys-641	448	29	zuberbier	zuberbier	NOUN
bionys-641	448	30	,	,	PUNCT
bionys-641	448	31	t.	t.	PROPN
bionys-641	448	32	(	(	PUNCT
bionys-641	448	33	2003	2003	NUM
bionys-641	448	34	)	)	PUNCT
bionys-641	448	35	.	.	PUNCT
bionys-641	449	1	ultraviolet	ultraviolet	ADJ
bionys-641	449	2	irradiation	irradiation	NOUN
bionys-641	449	3	induces	induce	VERB
bionys-641	449	4	apoptosis	apoptosis	NOUN
bionys-641	449	5	in	in	ADP
bionys-641	449	6	human	human	ADJ
bionys-641	449	7	immature	immature	ADJ
bionys-641	449	8	,	,	PUNCT
bionys-641	449	9	but	but	CCONJ
bionys-641	449	10	not	not	PART
bionys-641	449	11	in	in	ADP
bionys-641	449	12	skin	skin	NOUN
bionys-641	449	13	mast	mast	NOUN
bionys-641	449	14	cells	cell	NOUN
bionys-641	449	15	.	.	PUNCT
bionys-641	450	1	the	the	DET
bionys-641	450	2	journal	journal	NOUN
bionys-641	450	3	of	of	ADP
bionys-641	450	4	investigative	investigative	ADJ
bionys-641	450	5	dermatology	dermatology	NOUN
bionys-641	450	6	,	,	PUNCT
bionys-641	450	7	121(4	121(4	NUM
bionys-641	450	8	)	)	PUNCT
bionys-641	450	9	,	,	PUNCT
bionys-641	450	10	837–844	837–844	NUM
bionys-641	450	11	.	.	PUNCT
bionys-641	450	12	https://doi.org/10.1046/j.15231747.2003.12480.x	https://doi.org/10.1046/j.15231747.2003.12480.x	NOUN
bionys-641	450	13	hassig	hassig	PROPN
bionys-641	450	14	,	,	PUNCT
bionys-641	450	15	c.a	c.a	PROPN
bionys-641	450	16	.	.	PROPN
bionys-641	450	17	,	,	PUNCT
bionys-641	450	18	zeng	zeng	PROPN
bionys-641	450	19	,	,	PUNCT
bionys-641	450	20	f.-y	f.-y	PROPN
bionys-641	450	21	.	.	PUNCT
bionys-641	450	22	,	,	PUNCT
bionys-641	450	23	kung	kung	PROPN
bionys-641	450	24	,	,	PUNCT
bionys-641	450	25	p.	p.	PROPN
bionys-641	450	26	,	,	PUNCT
bionys-641	450	27	kiankarimi	kiankarimi	PROPN
bionys-641	450	28	,	,	PUNCT
bionys-641	450	29	m.	m.	NOUN
bionys-641	450	30	,	,	PUNCT
bionys-641	450	31	kim	kim	PROPN
bionys-641	450	32	,	,	PUNCT
bionys-641	450	33	s.	s.	PROPN
bionys-641	450	34	,	,	PUNCT
bionys-641	450	35	diaz	diaz	PROPN
bionys-641	450	36	,	,	PUNCT
bionys-641	450	37	p.w	p.w	PROPN
bionys-641	450	38	.	.	PROPN
bionys-641	450	39	,	,	PUNCT
bionys-641	450	40	zhai	zhai	PROPN
bionys-641	450	41	,	,	PUNCT
bionys-641	450	42	d.	d.	PROPN
bionys-641	450	43	,	,	PUNCT
bionys-641	450	44	welsh	welsh	PROPN
bionys-641	450	45	,	,	PUNCT
bionys-641	450	46	k.	k.	PROPN
bionys-641	450	47	,	,	PUNCT
bionys-641	450	48	morshedian	morshedian	PROPN
bionys-641	450	49	,	,	PUNCT
bionys-641	450	50	s.	s.	PROPN
bionys-641	450	51	,	,	PUNCT
bionys-641	450	52	su	su	PROPN
bionys-641	450	53	,	,	PUNCT
bionys-641	450	54	y.	y.	PROPN
bionys-641	450	55	,	,	PUNCT
bionys-641	450	56	o’keefe	o’keefe	PROPN
bionys-641	450	57	,	,	PUNCT
bionys-641	450	58	b.	b.	PROPN
bionys-641	450	59	,	,	PUNCT
bionys-641	450	60	newman	newman	PROPN
bionys-641	450	61	,	,	PUNCT
bionys-641	450	62	d.j	d.j	PROPN
bionys-641	450	63	.	.	PROPN
bionys-641	450	64	,	,	PUNCT
bionys-641	450	65	rusman	rusman	NOUN
bionys-641	450	66	,	,	PUNCT
bionys-641	450	67	y.	y.	PROPN
bionys-641	450	68	,	,	PUNCT
bionys-641	450	69	kaur	kaur	PROPN
bionys-641	450	70	,	,	PUNCT
bionys-641	450	71	h.	h.	PROPN
bionys-641	450	72	,	,	PUNCT
bionys-641	450	73	salomon	salomon	PROPN
bionys-641	450	74	,	,	PUNCT
bionys-641	450	75	c.e	c.e	PROPN
bionys-641	450	76	.	.	PROPN
bionys-641	450	77	,	,	PUNCT
bionys-641	450	78	brown	brown	PROPN
bionys-641	450	79	,	,	PUNCT
bionys-641	450	80	s.g	s.g	PROPN
bionys-641	450	81	.	.	PROPN
bionys-641	450	82	,	,	PUNCT
bionys-641	450	83	baire	baire	NOUN
bionys-641	450	84	,	,	PUNCT
bionys-641	450	85	b.	b.	PROPN
bionys-641	450	86	,	,	PUNCT
bionys-641	450	87	michel	michel	PROPN
bionys-641	450	88	,	,	PUNCT
bionys-641	450	89	a.r	a.r	PROPN
bionys-641	450	90	.	.	PROPN
bionys-641	450	91	,	,	PUNCT
bionys-641	450	92	hoye	hoye	PROPN
bionys-641	450	93	,	,	PUNCT
bionys-641	450	94	t.r	t.r	PROPN
bionys-641	450	95	.	.	PROPN
bionys-641	450	96	,	,	PUNCT
bionys-641	450	97	…	…	PUNCT
bionys-641	450	98	reed	reed	NOUN
bionys-641	450	99	,	,	PUNCT
bionys-641	450	100	j.c	j.c	PROPN
bionys-641	450	101	.	.	PROPN
bionys-641	450	102	(	(	PUNCT
bionys-641	450	103	2014	2014	NUM
bionys-641	450	104	)	)	PUNCT
bionys-641	450	105	.	.	PUNCT
bionys-641	451	1	ultra	ultra	ADJ
bionys-641	451	2	-	-	ADJ
bionys-641	451	3	high	high	ADJ
bionys-641	451	4	-	-	PUNCT
bionys-641	451	5	throughput	throughput	NOUN
bionys-641	451	6	screening	screening	NOUN
bionys-641	451	7	of	of	ADP
bionys-641	451	8	natural	natural	ADJ
bionys-641	451	9	product	product	NOUN
bionys-641	451	10	extracts	extract	NOUN
bionys-641	451	11	to	to	PART
bionys-641	451	12	identify	identify	VERB
bionys-641	451	13	proapoptotic	proapoptotic	ADJ
bionys-641	451	14	inhibitors	inhibitor	NOUN
bionys-641	451	15	of	of	ADP
bionys-641	451	16	bcl-2	bcl-2	NOUN
bionys-641	451	17	family	family	NOUN
bionys-641	451	18	proteins	protein	NOUN
bionys-641	451	19	.	.	PUNCT
bionys-641	452	1	slas	slas	PROPN
bionys-641	452	2	discovery	discovery	PROPN
bionys-641	452	3	,	,	PUNCT
bionys-641	452	4	19(8	19(8	NUM
bionys-641	452	5	)	)	PUNCT
bionys-641	452	6	,	,	PUNCT
bionys-641	452	7	1201–1211	1201–1211	NUM
bionys-641	452	8	.	.	PUNCT
bionys-641	453	1	https://doi	https://doi	NOUN
bionys-641	453	2	.	.	PUNCT
bionys-641	453	3	org/10.1177/1087057114536227	org/10.1177/1087057114536227	VERB
bionys-641	454	1	he	he	PRON
bionys-641	454	2	,	,	PUNCT
bionys-641	454	3	l.	l.	PROPN
bionys-641	454	4	,	,	PUNCT
bionys-641	454	5	zhang	zhang	PROPN
bionys-641	454	6	,	,	PUNCT
bionys-641	454	7	j.	j.	PROPN
bionys-641	454	8	,	,	PUNCT
bionys-641	454	9	zhao	zhao	PROPN
bionys-641	454	10	,	,	PUNCT
bionys-641	454	11	j.	j.	PROPN
bionys-641	454	12	,	,	PUNCT
bionys-641	454	13	ma	ma	PROPN
bionys-641	454	14	,	,	PUNCT
bionys-641	454	15	n.	n.	PROPN
bionys-641	454	16	,	,	PUNCT
bionys-641	454	17	kim	kim	PROPN
bionys-641	454	18	,	,	PUNCT
bionys-641	454	19	s.w	s.w	PROPN
bionys-641	454	20	.	.	PROPN
bionys-641	454	21	,	,	PUNCT
bionys-641	454	22	qiao	qiao	PROPN
bionys-641	454	23	,	,	PUNCT
bionys-641	454	24	s.	s.	PROPN
bionys-641	454	25	,	,	PUNCT
bionys-641	454	26	&	&	CCONJ
bionys-641	454	27	ma	ma	PROPN
bionys-641	454	28	,	,	PUNCT
bionys-641	454	29	x.	x.	NOUN
bionys-641	454	30	(	(	PUNCT
bionys-641	454	31	2018	2018	NUM
bionys-641	454	32	)	)	PUNCT
bionys-641	454	33	.	.	PUNCT
bionys-641	455	1	autophagy	autophagy	ADV
bionys-641	455	2	:	:	PUNCT
bionys-641	455	3	the	the	DET
bionys-641	455	4	last	last	ADJ
bionys-641	455	5	defense	defense	NOUN
bionys-641	455	6	against	against	ADP
bionys-641	455	7	cellular	cellular	ADJ
bionys-641	455	8	nutritional	nutritional	ADJ
bionys-641	455	9	stress	stress	NOUN
bionys-641	455	10	.	.	PUNCT
bionys-641	456	1	advances	advance	NOUN
bionys-641	456	2	in	in	ADP
bionys-641	456	3	nutrition	nutrition	NOUN
bionys-641	456	4	,	,	PUNCT
bionys-641	456	5	9(4	9(4	NUM
bionys-641	456	6	)	)	PUNCT
bionys-641	456	7	,	,	PUNCT
bionys-641	456	8	493–504	493–504	NUM
bionys-641	456	9	.	.	PUNCT
bionys-641	457	1	https://doi	https://doi	NOUN
bionys-641	457	2	.	.	PUNCT
bionys-641	458	1	org/10.1093	org/10.1093	PROPN
bionys-641	458	2	/	/	SYM
bionys-641	458	3	advances	advance	NOUN
bionys-641	458	4	/	/	SYM
bionys-641	458	5	nmy011	nmy011	PROPN
bionys-641	458	6	he	he	PRON
bionys-641	458	7	,	,	PUNCT
bionys-641	458	8	w.	w.	PROPN
bionys-641	458	9	,	,	PUNCT
bionys-641	458	10	wan	wan	PROPN
bionys-641	458	11	,	,	PUNCT
bionys-641	458	12	h.	h.	PROPN
bionys-641	458	13	,	,	PUNCT
bionys-641	458	14	hu	hu	PROPN
bionys-641	458	15	,	,	PUNCT
bionys-641	458	16	l.	l.	PROPN
bionys-641	458	17	,	,	PUNCT
bionys-641	458	18	chen	chen	PROPN
bionys-641	458	19	,	,	PUNCT
bionys-641	458	20	p.	p.	PROPN
bionys-641	458	21	,	,	PUNCT
bionys-641	458	22	wang	wang	PROPN
bionys-641	458	23	,	,	PUNCT
bionys-641	458	24	x.	x.	PROPN
bionys-641	458	25	,	,	PUNCT
bionys-641	458	26	huang	huang	PROPN
bionys-641	458	27	,	,	PUNCT
bionys-641	458	28	z.	z.	PROPN
bionys-641	458	29	,	,	PUNCT
bionys-641	458	30	yang	yang	PROPN
bionys-641	458	31	,	,	PUNCT
bionys-641	458	32	z.-h	z.-h	PROPN
bionys-641	458	33	.	.	PUNCT
bionys-641	458	34	,	,	PUNCT
bionys-641	458	35	zhong	zhong	PROPN
bionys-641	458	36	,	,	PUNCT
bionys-641	458	37	c.-q	c.-q	PROPN
bionys-641	458	38	.	.	PROPN
bionys-641	458	39	,	,	PUNCT
bionys-641	458	40	&	&	CCONJ
bionys-641	458	41	han	han	PROPN
bionys-641	458	42	,	,	PUNCT
bionys-641	458	43	j.	j.	PROPN
bionys-641	458	44	(	(	PUNCT
bionys-641	458	45	2015	2015	NUM
bionys-641	458	46	)	)	PUNCT
bionys-641	458	47	.	.	PUNCT
bionys-641	459	1	gasdermin	gasdermin	PROPN
bionys-641	459	2	d	d	PROPN
bionys-641	459	3	is	be	AUX
bionys-641	459	4	an	an	DET
bionys-641	459	5	executor	executor	NOUN
bionys-641	459	6	of	of	ADP
bionys-641	459	7	pyroptosis	pyroptosis	NOUN
bionys-641	459	8	and	and	CCONJ
bionys-641	459	9	required	require	VERB
bionys-641	459	10	for	for	ADP
bionys-641	459	11	interleukin-1β	interleukin-1β	ADJ
bionys-641	459	12	secretion	secretion	NOUN
bionys-641	459	13	.	.	PUNCT
bionys-641	460	1	cell	cell	NOUN
bionys-641	460	2	research	research	NOUN
bionys-641	460	3	,	,	PUNCT
bionys-641	460	4	25(12	25(12	NUM
bionys-641	460	5	)	)	PUNCT
bionys-641	460	6	,	,	PUNCT
bionys-641	460	7	1285–1298	1285–1298	NUM
bionys-641	460	8	.	.	PUNCT
bionys-641	461	1	https://doi.org/10.1038/	https://doi.org/10.1038/	NOUN
bionys-641	461	2	cr.2015.139	cr.2015.139	PROPN
bionys-641	461	3	helgoe	helgoe	NOUN
bionys-641	461	4	,	,	PUNCT
bionys-641	461	5	j.	j.	PROPN
bionys-641	461	6	,	,	PUNCT
bionys-641	461	7	davy	davy	PROPN
bionys-641	461	8	,	,	PUNCT
bionys-641	461	9	s.k	s.k	PROPN
bionys-641	461	10	.	.	PROPN
bionys-641	461	11	,	,	PUNCT
bionys-641	461	12	weis	weis	PROPN
bionys-641	461	13	,	,	PUNCT
bionys-641	461	14	v.m	v.m	PROPN
bionys-641	461	15	.	.	PROPN
bionys-641	461	16	,	,	PUNCT
bionys-641	461	17	&	&	CCONJ
bionys-641	461	18	rodriguezlanetty	rodriguezlanetty	PROPN
bionys-641	461	19	,	,	PUNCT
bionys-641	461	20	m.	m.	NOUN
bionys-641	461	21	(	(	PUNCT
bionys-641	461	22	2024	2024	NUM
bionys-641	461	23	)	)	PUNCT
bionys-641	461	24	.	.	PUNCT
bionys-641	462	1	triggers	trigger	NOUN
bionys-641	462	2	,	,	PUNCT
bionys-641	462	3	cascades	cascade	NOUN
bionys-641	462	4	,	,	PUNCT
bionys-641	462	5	and	and	CCONJ
bionys-641	462	6	endpoints	endpoint	NOUN
bionys-641	462	7	:	:	PUNCT
bionys-641	462	8	connecting	connect	VERB
bionys-641	462	9	the	the	DET
bionys-641	462	10	dots	dot	NOUN
bionys-641	462	11	of	of	ADP
bionys-641	462	12	coral	coral	ADJ
bionys-641	462	13	bleaching	bleaching	NOUN
bionys-641	462	14	mechanisms	mechanism	NOUN
bionys-641	462	15	.	.	PUNCT
bionys-641	463	1	biological	biological	ADJ
bionys-641	463	2	reviews	review	NOUN
bionys-641	463	3	,	,	PUNCT
bionys-641	463	4	99(3	99(3	NUM
bionys-641	463	5	)	)	PUNCT
bionys-641	463	6	,	,	PUNCT
bionys-641	463	7	715–752	715–752	NUM
bionys-641	463	8	.	.	PUNCT
bionys-641	464	1	https://doi.org/10.1111/brv.13042	https://doi.org/10.1111/brv.13042	PROPN
bionys-641	464	2	hersh	hersh	PROPN
bionys-641	464	3	,	,	PUNCT
bionys-641	464	4	d.	d.	PROPN
bionys-641	464	5	,	,	PUNCT
bionys-641	464	6	monack	monack	NOUN
bionys-641	464	7	,	,	PUNCT
bionys-641	464	8	d.m	d.m	PROPN
bionys-641	464	9	.	.	PROPN
bionys-641	464	10	,	,	PUNCT
bionys-641	464	11	smith	smith	PROPN
bionys-641	464	12	,	,	PUNCT
bionys-641	464	13	m.r	m.r	PROPN
bionys-641	464	14	.	.	PROPN
bionys-641	464	15	,	,	PUNCT
bionys-641	464	16	ghori	ghori	PROPN
bionys-641	464	17	,	,	PUNCT
bionys-641	464	18	n.	n.	PROPN
bionys-641	464	19	,	,	PUNCT
bionys-641	464	20	falkow	falkow	NOUN
bionys-641	464	21	,	,	PUNCT
bionys-641	464	22	s.	s.	PROPN
bionys-641	464	23	,	,	PUNCT
bionys-641	464	24	&	&	CCONJ
bionys-641	464	25	zychlinsky	zychlinsky	PROPN
bionys-641	464	26	,	,	PUNCT
bionys-641	464	27	a.	a.	NOUN
bionys-641	464	28	(	(	PUNCT
bionys-641	464	29	1999	1999	NUM
bionys-641	464	30	)	)	PUNCT
bionys-641	464	31	.	.	PUNCT
bionys-641	465	1	the	the	DET
bionys-641	465	2	salmonella	salmonella	PROPN
bionys-641	465	3	invasin	invasin	VERB
bionys-641	465	4	sipb	sipb	ADJ
bionys-641	465	5	induces	induce	VERB
bionys-641	465	6	macrophage	macrophage	ADJ
bionys-641	465	7	apoptosis	apoptosis	NOUN
bionys-641	465	8	by	by	ADP
bionys-641	465	9	binding	bind	VERB
bionys-641	465	10	to	to	ADP
bionys-641	465	11	caspase-1	caspase-1	PROPN
bionys-641	465	12	.	.	PUNCT
bionys-641	466	1	proceedings	proceeding	NOUN
bionys-641	466	2	of	of	ADP
bionys-641	466	3	the	the	DET
bionys-641	466	4	national	national	PROPN
bionys-641	466	5	academy	academy	PROPN
bionys-641	466	6	of	of	ADP
bionys-641	466	7	sciences	sciences	PROPN
bionys-641	466	8	of	of	ADP
bionys-641	466	9	the	the	DET
bionys-641	466	10	united	united	PROPN
bionys-641	466	11	states	states	PROPN
bionys-641	466	12	of	of	ADP
bionys-641	466	13	america	america	PROPN
bionys-641	466	14	,	,	PUNCT
bionys-641	466	15	96(5	96(5	NUM
bionys-641	466	16	)	)	PUNCT
bionys-641	466	17	,	,	PUNCT
bionys-641	466	18	2396–2401	2396–2401	NUM
bionys-641	466	19	.	.	PUNCT
bionys-641	467	1	https://doi	https://doi	NOUN
bionys-641	467	2	.	.	PUNCT
bionys-641	467	3	org/10.1073	org/10.1073	PROPN
bionys-641	467	4	/	/	SYM
bionys-641	467	5	pnas.96.5.2396	pnas.96.5.2396	PROPN
bionys-641	467	6	hilbi	hilbi	PROPN
bionys-641	467	7	,	,	PUNCT
bionys-641	467	8	h.	h.	PROPN
bionys-641	467	9	,	,	PUNCT
bionys-641	467	10	moss	moss	NOUN
bionys-641	467	11	,	,	PUNCT
bionys-641	467	12	j.e	j.e	PROPN
bionys-641	467	13	.	.	PROPN
bionys-641	467	14	,	,	PUNCT
bionys-641	467	15	hersh	hersh	PROPN
bionys-641	467	16	,	,	PUNCT
bionys-641	467	17	d.	d.	PROPN
bionys-641	467	18	,	,	PUNCT
bionys-641	467	19	chen	chen	PROPN
bionys-641	467	20	,	,	PUNCT
bionys-641	467	21	y.	y.	PROPN
bionys-641	467	22	,	,	PUNCT
bionys-641	467	23	arondel	arondel	PROPN
bionys-641	467	24	,	,	PUNCT
bionys-641	467	25	j.	j.	PROPN
bionys-641	467	26	,	,	PUNCT
bionys-641	467	27	banerjee	banerjee	PROPN
bionys-641	467	28	,	,	PUNCT
bionys-641	467	29	s.	s.	PROPN
bionys-641	467	30	,	,	PUNCT
bionys-641	467	31	flavell	flavell	PROPN
bionys-641	467	32	,	,	PUNCT
bionys-641	467	33	r.a	r.a	PROPN
bionys-641	467	34	.	.	PROPN
bionys-641	467	35	,	,	PUNCT
bionys-641	467	36	yuan	yuan	PROPN
bionys-641	467	37	,	,	PUNCT
bionys-641	467	38	j.	j.	PROPN
bionys-641	467	39	,	,	PUNCT
bionys-641	467	40	sansonetti	sansonetti	PROPN
bionys-641	467	41	,	,	PUNCT
bionys-641	467	42	p.j	p.j	PROPN
bionys-641	467	43	.	.	PROPN
bionys-641	467	44	,	,	PUNCT
bionys-641	467	45	&	&	CCONJ
bionys-641	467	46	zychlinsky	zychlinsky	PROPN
bionys-641	467	47	,	,	PUNCT
bionys-641	467	48	a.	a.	NOUN
bionys-641	467	49	(	(	PUNCT
bionys-641	467	50	1998	1998	NUM
bionys-641	467	51	)	)	PUNCT
bionys-641	467	52	.	.	PUNCT
bionys-641	468	1	shigellainduced	shigellainduced	ADJ
bionys-641	468	2	apoptosis	apoptosis	NOUN
bionys-641	468	3	is	be	AUX
bionys-641	468	4	dependent	dependent	ADJ
bionys-641	468	5	on	on	ADP
bionys-641	468	6	caspase-1	caspase-1	NUM
bionys-641	468	7	which	which	PRON
bionys-641	468	8	binds	bind	VERB
bionys-641	468	9	to	to	ADP
bionys-641	468	10	ipab	ipab	NOUN
bionys-641	468	11	.	.	PUNCT
bionys-641	469	1	the	the	DET
bionys-641	469	2	journal	journal	NOUN
bionys-641	469	3	of	of	ADP
bionys-641	469	4	biological	biological	ADJ
bionys-641	469	5	chemistry	chemistry	NOUN
bionys-641	469	6	,	,	PUNCT
bionys-641	469	7	273(49	273(49	NUM
bionys-641	469	8	)	)	PUNCT
bionys-641	469	9	,	,	PUNCT
bionys-641	469	10	32895–32900	32895–32900	NUM
bionys-641	469	11	.	.	PUNCT
bionys-641	470	1	https://doi.org/10.1074/	https://doi.org/10.1074/	NOUN
bionys-641	470	2	jbc.273.49.32895	jbc.273.49.32895	PROPN
bionys-641	471	1	hincelin	hincelin	PROPN
bionys-641	471	2	-	-	PUNCT
bionys-641	471	3	mery	mery	PROPN
bionys-641	471	4	,	,	PUNCT
bionys-641	471	5	a.	a.	PROPN
bionys-641	471	6	,	,	PUNCT
bionys-641	471	7	nicolas	nicolas	PROPN
bionys-641	471	8	,	,	PUNCT
bionys-641	471	9	x.	x.	NOUN
bionys-641	471	10	,	,	PUNCT
bionys-641	471	11	cantalloube	cantalloube	NOUN
bionys-641	471	12	,	,	PUNCT
bionys-641	471	13	c.	c.	NOUN
bionys-641	471	14	,	,	PUNCT
bionys-641	471	15	pomponio	pomponio	PROPN
bionys-641	471	16	,	,	PUNCT
bionys-641	471	17	r.	r.	PROPN
bionys-641	471	18	,	,	PUNCT
bionys-641	471	19	lewanczyk	lewanczyk	PROPN
bionys-641	471	20	,	,	PUNCT
bionys-641	471	21	p.	p.	NOUN
bionys-641	471	22	,	,	PUNCT
bionys-641	471	23	benamor	benamor	PROPN
bionys-641	471	24	,	,	PUNCT
bionys-641	471	25	m.	m.	NOUN
bionys-641	471	26	,	,	PUNCT
bionys-641	471	27	ofengeim	ofengeim	PROPN
bionys-641	471	28	,	,	PUNCT
bionys-641	471	29	d.	d.	PROPN
bionys-641	471	30	,	,	PUNCT
bionys-641	471	31	krupka	krupka	PROPN
bionys-641	471	32	,	,	PUNCT
bionys-641	471	33	e.	e.	PROPN
bionys-641	471	34	,	,	PUNCT
bionys-641	471	35	hsiao	hsiao	PROPN
bionys-641	471	36	-	-	NOUN
bionys-641	471	37	nakamoto	nakamoto	NOUN
bionys-641	471	38	,	,	PUNCT
bionys-641	471	39	j.	j.	PROPN
bionys-641	471	40	,	,	PUNCT
bionys-641	471	41	eastenson	eastenson	PROPN
bionys-641	471	42	,	,	PUNCT
bionys-641	471	43	a.	a.	NOUN
bionys-641	471	44	,	,	PUNCT
bionys-641	471	45	&	&	CCONJ
bionys-641	471	46	atassi	atassi	PROPN
bionys-641	471	47	,	,	PUNCT
bionys-641	471	48	n.	n.	PROPN
bionys-641	471	49	(	(	PUNCT
bionys-641	471	50	2024	2024	NUM
bionys-641	471	51	)	)	PUNCT
bionys-641	471	52	.	.	PUNCT
bionys-641	472	1	safety	safety	NOUN
bionys-641	472	2	,	,	PUNCT
bionys-641	472	3	pharmacokinetics	pharmacokinetic	NOUN
bionys-641	472	4	,	,	PUNCT
bionys-641	472	5	and	and	CCONJ
bionys-641	472	6	target	target	NOUN
bionys-641	472	7	engagement	engagement	NOUN
bionys-641	472	8	of	of	ADP
bionys-641	472	9	a	a	DET
bionys-641	472	10	brain	brain	NOUN
bionys-641	472	11	penetrant	penetrant	NOUN
bionys-641	472	12	ripk1	ripk1	NOUN
bionys-641	472	13	inhibitor	inhibitor	NOUN
bionys-641	472	14	,	,	PUNCT
bionys-641	472	15	sar443820	sar443820	NOUN
bionys-641	472	16	(	(	PUNCT
bionys-641	472	17	dnl788	dnl788	PROPN
bionys-641	472	18	)	)	PUNCT
bionys-641	472	19	,	,	PUNCT
bionys-641	472	20	in	in	ADP
bionys-641	472	21	healthy	healthy	ADJ
bionys-641	472	22	adult	adult	NOUN
bionys-641	472	23	participants	participant	NOUN
bionys-641	472	24	.	.	PUNCT
bionys-641	473	1	clinical	clinical	ADJ
bionys-641	473	2	and	and	CCONJ
bionys-641	473	3	translational	translational	ADJ
bionys-641	473	4	science	science	NOUN
bionys-641	473	5	,	,	PUNCT
bionys-641	473	6	17(1	17(1	NUM
bionys-641	473	7	)	)	PUNCT
bionys-641	473	8	,	,	PUNCT
bionys-641	473	9	e13690	e13690	NOUN
bionys-641	473	10	.	.	PUNCT
bionys-641	474	1	https://	https://	PROPN
bionys-641	474	2	doi.org/10.1111/cts.13690	doi.org/10.1111/cts.13690	PROPN
bionys-641	474	3	hirayama	hirayama	PROPN
bionys-641	474	4	,	,	PUNCT
bionys-641	474	5	d.	d.	PROPN
bionys-641	474	6	,	,	PUNCT
bionys-641	474	7	iida	iida	PROPN
bionys-641	474	8	,	,	PUNCT
bionys-641	474	9	t.	t.	PROPN
bionys-641	474	10	,	,	PUNCT
bionys-641	474	11	&	&	CCONJ
bionys-641	474	12	nakase	nakase	PROPN
bionys-641	474	13	,	,	PUNCT
bionys-641	474	14	h.	h.	PROPN
bionys-641	474	15	(	(	PUNCT
bionys-641	474	16	2017	2017	NUM
bionys-641	474	17	)	)	PUNCT
bionys-641	474	18	.	.	PUNCT
bionys-641	475	1	the	the	DET
bionys-641	475	2	phagocytic	phagocytic	ADJ
bionys-641	475	3	function	function	NOUN
bionys-641	475	4	of	of	ADP
bionys-641	475	5	macrophage	macrophage	NOUN
bionys-641	475	6	-	-	PUNCT
bionys-641	475	7	enforcing	enforce	VERB
bionys-641	475	8	innate	innate	ADJ
bionys-641	475	9	immunity	immunity	NOUN
bionys-641	475	10	and	and	CCONJ
bionys-641	475	11	tissue	tissue	NOUN
bionys-641	475	12	homeostasis	homeostasis	NOUN
bionys-641	475	13	.	.	PUNCT
bionys-641	476	1	international	international	ADJ
bionys-641	476	2	journal	journal	NOUN
bionys-641	476	3	of	of	ADP
bionys-641	476	4	molecular	molecular	ADJ
bionys-641	476	5	sciences	science	NOUN
bionys-641	476	6	,	,	PUNCT
bionys-641	476	7	19(1	19(1	NUM
bionys-641	476	8	)	)	PUNCT
bionys-641	476	9	,	,	PUNCT
bionys-641	476	10	92	92	NUM
bionys-641	476	11	.	.	PUNCT
bionys-641	477	1	https://doi.org/10.3390/ijms19010092	https://doi.org/10.3390/ijms19010092	VERB
bionys-641	477	2	holze	holze	PROPN
bionys-641	477	3	,	,	PUNCT
bionys-641	477	4	c.	c.	PROPN
bionys-641	477	5	,	,	PUNCT
bionys-641	477	6	michaudel	michaudel	PROPN
bionys-641	477	7	,	,	PUNCT
bionys-641	477	8	c.	c.	PROPN
bionys-641	477	9	,	,	PUNCT
bionys-641	477	10	mackowiak	mackowiak	PROPN
bionys-641	477	11	,	,	PUNCT
bionys-641	477	12	c.	c.	PROPN
bionys-641	477	13	,	,	PUNCT
bionys-641	477	14	haas	haas	PROPN
bionys-641	477	15	,	,	PUNCT
bionys-641	477	16	d.a	d.a	PROPN
bionys-641	477	17	.	.	PROPN
bionys-641	477	18	,	,	PUNCT
bionys-641	477	19	benda	benda	PROPN
bionys-641	477	20	,	,	PUNCT
bionys-641	477	21	c.	c.	PROPN
bionys-641	477	22	,	,	PUNCT
bionys-641	477	23	hubel	hubel	NOUN
bionys-641	477	24	,	,	PUNCT
bionys-641	477	25	p.	p.	NOUN
bionys-641	477	26	,	,	PUNCT
bionys-641	477	27	pennemann	pennemann	PROPN
bionys-641	477	28	,	,	PUNCT
bionys-641	477	29	f.l	f.l	PROPN
bionys-641	477	30	.	.	PROPN
bionys-641	477	31	,	,	PUNCT
bionys-641	477	32	schnepf	schnepf	ADJ
bionys-641	477	33	,	,	PUNCT
bionys-641	477	34	d.	d.	PROPN
bionys-641	477	35	,	,	PUNCT
bionys-641	477	36	wettmarshausen	wettmarshausen	PROPN
bionys-641	477	37	,	,	PUNCT
bionys-641	477	38	j.	j.	PROPN
bionys-641	477	39	,	,	PUNCT
bionys-641	477	40	braun	braun	NOUN
bionys-641	477	41	,	,	PUNCT
bionys-641	477	42	m.	m.	NOUN
bionys-641	477	43	,	,	PUNCT
bionys-641	477	44	leung	leung	PROPN
bionys-641	477	45	,	,	PUNCT
bionys-641	477	46	d.w	d.w	PROPN
bionys-641	477	47	.	.	PROPN
bionys-641	477	48	,	,	PUNCT
bionys-641	477	49	amarasinghe	amarasinghe	PROPN
bionys-641	477	50	,	,	PUNCT
bionys-641	477	51	g.	g.	PROPN
bionys-641	477	52	k.	k.	PROPN
bionys-641	477	53	,	,	PUNCT
bionys-641	477	54	perocchi	perocchi	PROPN
bionys-641	477	55	,	,	PUNCT
bionys-641	477	56	f.	f.	PROPN
bionys-641	477	57	,	,	PUNCT
bionys-641	477	58	staeheli	staeheli	ADJ
bionys-641	477	59	,	,	PUNCT
bionys-641	477	60	p.	p.	NOUN
bionys-641	477	61	,	,	PUNCT
bionys-641	477	62	ryffel	ryffel	NOUN
bionys-641	477	63	,	,	PUNCT
bionys-641	477	64	b.	b.	PROPN
bionys-641	477	65	,	,	PUNCT
bionys-641	477	66	&	&	CCONJ
bionys-641	477	67	pichlmair	pichlmair	PROPN
bionys-641	477	68	,	,	PUNCT
bionys-641	477	69	a.	a.	NOUN
bionys-641	477	70	(	(	PUNCT
bionys-641	477	71	2018	2018	NUM
bionys-641	477	72	)	)	PUNCT
bionys-641	477	73	.	.	PUNCT
bionys-641	478	1	oxeiptosis	oxeiptosis	PROPN
bionys-641	478	2	,	,	PUNCT
bionys-641	478	3	a	a	DET
bionys-641	478	4	ros	ros	PROPN
bionys-641	478	5	-	-	PUNCT
bionys-641	478	6	induced	induce	VERB
bionys-641	478	7	caspaseindependent	caspaseindependent	ADJ
bionys-641	478	8	apoptosis	apoptosis	NOUN
bionys-641	478	9	-	-	PUNCT
bionys-641	478	10	like	like	ADJ
bionys-641	478	11	cell	cell	NOUN
bionys-641	478	12	-	-	PUNCT
bionys-641	478	13	death	death	NOUN
bionys-641	478	14	pathway	pathway	NOUN
bionys-641	478	15	.	.	PUNCT
bionys-641	479	1	nature	nature	NOUN
bionys-641	479	2	immunology	immunology	NOUN
bionys-641	479	3	,	,	PUNCT
bionys-641	479	4	19(2	19(2	NUM
bionys-641	479	5	)	)	PUNCT
bionys-641	479	6	,	,	PUNCT
bionys-641	479	7	130–140	130–140	NUM
bionys-641	479	8	.	.	PUNCT
bionys-641	480	1	https://doi	https://doi	NOUN
bionys-641	480	2	.	.	PUNCT
bionys-641	480	3	org/10.1038	org/10.1038	PROPN
bionys-641	480	4	/	/	SYM
bionys-641	480	5	s41590	s41590	PROPN
bionys-641	480	6	-	-	PUNCT
bionys-641	480	7	017	017	NUM
bionys-641	480	8	-	-	PUNCT
bionys-641	480	9	0013	0013	NUM
bionys-641	480	10	-	-	PUNCT
bionys-641	480	11	y	y	PROPN
bionys-641	480	12	biologica	biologica	PROPN
bionys-641	480	13	nyssana	nyssana	PROPN
bionys-641	480	14	●	●	PUNCT
bionys-641	480	15	16	16	NUM
bionys-641	480	16	(	(	PUNCT
bionys-641	480	17	2	2	NUM
bionys-641	480	18	)	)	PUNCT
bionys-641	480	19	december	december	PROPN
bionys-641	480	20	2025	2025	NUM
bionys-641	480	21	:	:	PUNCT
bionys-641	480	22	liana	liana	NOUN
bionys-641	480	23	et	et	PROPN
bionys-641	480	24	al	al	PROPN
bionys-641	480	25	.	.	PUNCT
bionys-641	481	1	●	●	PUNCT
bionys-641	481	2	cell	cell	NOUN
bionys-641	481	3	deaths	death	NOUN
bionys-641	481	4	and	and	CCONJ
bionys-641	481	5	their	their	PRON
bionys-641	481	6	associated	associate	VERB
bionys-641	481	7	mechanisms	mechanism	NOUN
bionys-641	481	8	hurle	hurle	NOUN
bionys-641	481	9	,	,	PUNCT
bionys-641	481	10	j.m	j.m	PROPN
bionys-641	481	11	.	.	PROPN
bionys-641	481	12	&	&	CCONJ
bionys-641	481	13	ganan	ganan	PROPN
bionys-641	481	14	,	,	PUNCT
bionys-641	481	15	y.	y.	PROPN
bionys-641	481	16	(	(	PUNCT
bionys-641	481	17	1986	1986	NUM
bionys-641	481	18	)	)	PUNCT
bionys-641	481	19	.	.	PUNCT
bionys-641	482	1	interdigital	interdigital	ADJ
bionys-641	482	2	tissue	tissue	NOUN
bionys-641	482	3	chondrogenesis	chondrogenesis	NOUN
bionys-641	482	4	induced	induce	VERB
bionys-641	482	5	by	by	ADP
bionys-641	482	6	surgical	surgical	ADJ
bionys-641	482	7	removal	removal	NOUN
bionys-641	482	8	of	of	ADP
bionys-641	482	9	the	the	DET
bionys-641	482	10	ectoderm	ectoderm	NOUN
bionys-641	482	11	in	in	ADP
bionys-641	482	12	the	the	DET
bionys-641	482	13	embryonic	embryonic	ADJ
bionys-641	482	14	chick	chick	NOUN
bionys-641	482	15	leg	leg	NOUN
bionys-641	482	16	bud	bud	NOUN
bionys-641	482	17	.	.	PUNCT
bionys-641	483	1	development	development	NOUN
bionys-641	483	2	,	,	PUNCT
bionys-641	483	3	94(1	94(1	NUM
bionys-641	483	4	)	)	PUNCT
bionys-641	483	5	,	,	PUNCT
bionys-641	483	6	231–244	231–244	NUM
bionys-641	483	7	.	.	PUNCT
bionys-641	484	1	jacamo	jacamo	PROPN
bionys-641	484	2	,	,	PUNCT
bionys-641	484	3	r.o	r.o	PROPN
bionys-641	484	4	.	.	PROPN
bionys-641	484	5	,	,	PUNCT
bionys-641	484	6	zhang	zhang	PROPN
bionys-641	484	7	,	,	PUNCT
bionys-641	484	8	q.	q.	PROPN
bionys-641	484	9	,	,	PUNCT
bionys-641	484	10	mcqueen	mcqueen	PROPN
bionys-641	484	11	,	,	PUNCT
bionys-641	484	12	t.	t.	PROPN
bionys-641	484	13	,	,	PUNCT
bionys-641	484	14	davis	davis	PROPN
bionys-641	484	15	,	,	PUNCT
bionys-641	484	16	r.e	r.e	PROPN
bionys-641	484	17	.	.	PROPN
bionys-641	484	18	,	,	PUNCT
bionys-641	484	19	konopleva	konopleva	PROPN
bionys-641	484	20	,	,	PUNCT
bionys-641	484	21	m.	m.	NOUN
bionys-641	484	22	,	,	PUNCT
bionys-641	484	23	&	&	CCONJ
bionys-641	484	24	andreeff	andreeff	PROPN
bionys-641	484	25	,	,	PUNCT
bionys-641	484	26	m.	m.	NOUN
bionys-641	484	27	(	(	PUNCT
bionys-641	484	28	2016	2016	NUM
bionys-641	484	29	)	)	PUNCT
bionys-641	484	30	.	.	PUNCT
bionys-641	485	1	silencing	silence	VERB
bionys-641	485	2	tg2	tg2	ADJ
bionys-641	485	3	in	in	ADP
bionys-641	485	4	acute	acute	ADJ
bionys-641	485	5	myeloid	myeloid	ADJ
bionys-641	485	6	leukemia	leukemia	NOUN
bionys-641	485	7	.	.	PUNCT
bionys-641	486	1	possible	possible	ADJ
bionys-641	486	2	role	role	NOUN
bionys-641	486	3	of	of	ADP
bionys-641	486	4	tg2	tg2	ADJ
bionys-641	486	5	in	in	ADP
bionys-641	486	6	microenvironment	microenvironment	NOUN
bionys-641	486	7	-	-	PUNCT
bionys-641	486	8	mediated	mediate	VERB
bionys-641	486	9	chemoresistance	chemoresistance	NOUN
bionys-641	486	10	.	.	PUNCT
bionys-641	487	1	blood	blood	NOUN
bionys-641	487	2	,	,	PUNCT
bionys-641	487	3	128(22	128(22	NUM
bionys-641	487	4	)	)	PUNCT
bionys-641	487	5	,	,	PUNCT
bionys-641	487	6	5087	5087	NUM
bionys-641	487	7	.	.	PUNCT
bionys-641	488	1	https://doi	https://doi	PROPN
bionys-641	488	2	.	.	PUNCT
bionys-641	488	3	org/10.1182	org/10.1182	PROPN
bionys-641	488	4	/	/	SYM
bionys-641	488	5	blood.v128.22.5087.5087	blood.v128.22.5087.5087	PROPN
bionys-641	488	6	jiang	jiang	PROPN
bionys-641	488	7	,	,	PUNCT
bionys-641	488	8	z.	z.	PROPN
bionys-641	488	9	,	,	PUNCT
bionys-641	488	10	zhou	zhou	PROPN
bionys-641	488	11	,	,	PUNCT
bionys-641	488	12	y.	y.	PROPN
bionys-641	488	13	,	,	PUNCT
bionys-641	488	14	&	&	CCONJ
bionys-641	488	15	huang	huang	PROPN
bionys-641	488	16	,	,	PUNCT
bionys-641	488	17	j.	j.	PROPN
bionys-641	488	18	(	(	PUNCT
bionys-641	488	19	2021	2021	NUM
bionys-641	488	20	)	)	PUNCT
bionys-641	488	21	.	.	PUNCT
bionys-641	489	1	a	a	DET
bionys-641	489	2	combination	combination	NOUN
bionys-641	489	3	of	of	ADP
bionys-641	489	4	biomarkers	biomarker	NOUN
bionys-641	489	5	predict	predict	VERB
bionys-641	489	6	response	response	NOUN
bionys-641	489	7	to	to	ADP
bionys-641	489	8	immune	immune	ADJ
bionys-641	489	9	checkpoint	checkpoint	NOUN
bionys-641	489	10	blockade	blockade	NOUN
bionys-641	489	11	therapy	therapy	NOUN
bionys-641	489	12	in	in	ADP
bionys-641	489	13	non	non	ADJ
bionys-641	489	14	-	-	ADJ
bionys-641	489	15	small	small	ADJ
bionys-641	489	16	cell	cell	NOUN
bionys-641	489	17	lung	lung	NOUN
bionys-641	489	18	cancer	cancer	NOUN
bionys-641	489	19	.	.	PUNCT
bionys-641	490	1	frontiers	frontier	NOUN
bionys-641	490	2	in	in	ADP
bionys-641	490	3	immunology	immunology	NOUN
bionys-641	490	4	,	,	PUNCT
bionys-641	490	5	12	12	NUM
bionys-641	490	6	,	,	PUNCT
bionys-641	490	7	813331	813331	NUM
bionys-641	490	8	.	.	PUNCT
bionys-641	491	1	https://doi.org/10.3389/	https://doi.org/10.3389/	PROPN
bionys-641	491	2	fimmu.2021.813331	fimmu.2021.813331	PROPN
bionys-641	491	3	jorch	jorch	NOUN
bionys-641	491	4	,	,	PUNCT
bionys-641	491	5	s.k	s.k	PROPN
bionys-641	491	6	.	.	PROPN
bionys-641	491	7	&	&	CCONJ
bionys-641	491	8	kubes	kubes	PROPN
bionys-641	491	9	,	,	PUNCT
bionys-641	491	10	p.	p.	NOUN
bionys-641	491	11	(	(	PUNCT
bionys-641	491	12	2017	2017	NUM
bionys-641	491	13	)	)	PUNCT
bionys-641	491	14	.	.	PUNCT
bionys-641	492	1	an	an	DET
bionys-641	492	2	emerging	emerge	VERB
bionys-641	492	3	role	role	NOUN
bionys-641	492	4	for	for	ADP
bionys-641	492	5	neutrophil	neutrophil	ADJ
bionys-641	492	6	extracellular	extracellular	ADJ
bionys-641	492	7	traps	trap	NOUN
bionys-641	492	8	in	in	ADP
bionys-641	492	9	noninfectious	noninfectious	ADJ
bionys-641	492	10	disease	disease	NOUN
bionys-641	492	11	.	.	PUNCT
bionys-641	493	1	nature	nature	NOUN
bionys-641	493	2	medicine	medicine	NOUN
bionys-641	493	3	,	,	PUNCT
bionys-641	493	4	23(3	23(3	NUM
bionys-641	493	5	)	)	PUNCT
bionys-641	493	6	,	,	PUNCT
bionys-641	493	7	279–287	279–287	NUM
bionys-641	493	8	.	.	PUNCT
bionys-641	494	1	https://	https://	PROPN
bionys-641	494	2	doi.org/10.1038/nm.4294	doi.org/10.1038/nm.4294	PROPN
bionys-641	494	3	kerr	kerr	PROPN
bionys-641	494	4	,	,	PUNCT
bionys-641	494	5	j.f	j.f	PROPN
bionys-641	494	6	.	.	PROPN
bionys-641	494	7	(	(	PUNCT
bionys-641	494	8	1971	1971	NUM
bionys-641	494	9	)	)	PUNCT
bionys-641	494	10	.	.	PUNCT
bionys-641	495	1	shrinkage	shrinkage	NOUN
bionys-641	495	2	necrosis	necrosis	NOUN
bionys-641	495	3	:	:	PUNCT
bionys-641	495	4	a	a	DET
bionys-641	495	5	distinct	distinct	ADJ
bionys-641	495	6	mode	mode	NOUN
bionys-641	495	7	of	of	ADP
bionys-641	495	8	cellular	cellular	ADJ
bionys-641	495	9	death	death	NOUN
bionys-641	495	10	.	.	PUNCT
bionys-641	496	1	the	the	DET
bionys-641	496	2	journal	journal	PROPN
bionys-641	496	3	of	of	ADP
bionys-641	496	4	pathology	pathology	PROPN
bionys-641	496	5	,	,	PUNCT
bionys-641	496	6	105(1	105(1	NUM
bionys-641	496	7	)	)	PUNCT
bionys-641	496	8	,	,	PUNCT
bionys-641	496	9	13–20	13–20	NUM
bionys-641	496	10	.	.	PROPN
bionys-641	496	11	https://doi.org/10.1002/path.1711050103	https://doi.org/10.1002/path.1711050103	PROPN
bionys-641	496	12	khan	khan	PROPN
bionys-641	496	13	,	,	PUNCT
bionys-641	496	14	s.	s.	PROPN
bionys-641	496	15	,	,	PUNCT
bionys-641	496	16	fatima	fatima	PROPN
bionys-641	496	17	,	,	PUNCT
bionys-641	496	18	k.	k.	PROPN
bionys-641	496	19	,	,	PUNCT
bionys-641	496	20	&	&	CCONJ
bionys-641	496	21	malik	malik	PROPN
bionys-641	496	22	,	,	PUNCT
bionys-641	496	23	f.	f.	PROPN
bionys-641	496	24	(	(	PUNCT
bionys-641	496	25	2022	2022	NUM
bionys-641	496	26	)	)	PUNCT
bionys-641	496	27	.	.	PUNCT
bionys-641	497	1	understanding	understand	VERB
bionys-641	497	2	the	the	DET
bionys-641	497	3	cell	cell	NOUN
bionys-641	497	4	survival	survival	NOUN
bionys-641	497	5	mechanism	mechanism	NOUN
bionys-641	497	6	of	of	ADP
bionys-641	497	7	anoikis	anoiki	NOUN
bionys-641	497	8	-	-	PUNCT
bionys-641	497	9	resistant	resistant	ADJ
bionys-641	497	10	cancer	cancer	NOUN
bionys-641	497	11	cells	cell	NOUN
bionys-641	497	12	during	during	ADP
bionys-641	497	13	different	different	ADJ
bionys-641	497	14	steps	step	NOUN
bionys-641	497	15	of	of	ADP
bionys-641	497	16	metastasis	metastasis	NOUN
bionys-641	497	17	.	.	PUNCT
bionys-641	498	1	clinical	clinical	ADJ
bionys-641	498	2	&	&	CCONJ
bionys-641	498	3	experimental	experimental	ADJ
bionys-641	498	4	metastasis	metastasis	NOUN
bionys-641	498	5	,	,	PUNCT
bionys-641	498	6	39	39	NUM
bionys-641	498	7	,	,	PUNCT
bionys-641	498	8	715–726	715–726	NUM
bionys-641	498	9	.	.	PUNCT
bionys-641	499	1	https://doi.org/10.1007/s10585-02210172-9	https://doi.org/10.1007/s10585-02210172-9	PROPN
bionys-641	499	2	khoury	khoury	PROPN
bionys-641	499	3	,	,	PUNCT
bionys-641	499	4	m.k	m.k	PROPN
bionys-641	499	5	.	.	PROPN
bionys-641	499	6	,	,	PUNCT
bionys-641	499	7	gupta	gupta	PROPN
bionys-641	499	8	,	,	PUNCT
bionys-641	499	9	k.	k.	PROPN
bionys-641	499	10	,	,	PUNCT
bionys-641	499	11	franco	franco	PROPN
bionys-641	499	12	,	,	PUNCT
bionys-641	499	13	s.r	s.r	PROPN
bionys-641	499	14	.	.	PROPN
bionys-641	499	15	,	,	PUNCT
bionys-641	499	16	&	&	CCONJ
bionys-641	499	17	liu	liu	PROPN
bionys-641	499	18	,	,	PUNCT
bionys-641	499	19	b.	b.	PROPN
bionys-641	499	20	(	(	PUNCT
bionys-641	499	21	2020	2020	NUM
bionys-641	499	22	)	)	PUNCT
bionys-641	499	23	.	.	PUNCT
bionys-641	500	1	necroptosis	necroptosis	NOUN
bionys-641	500	2	in	in	ADP
bionys-641	500	3	the	the	DET
bionys-641	500	4	pathophysiology	pathophysiology	NOUN
bionys-641	500	5	of	of	ADP
bionys-641	500	6	disease	disease	NOUN
bionys-641	500	7	.	.	PUNCT
bionys-641	501	1	the	the	DET
bionys-641	501	2	american	american	PROPN
bionys-641	501	3	journal	journal	PROPN
bionys-641	501	4	of	of	ADP
bionys-641	501	5	pathology	pathology	PROPN
bionys-641	501	6	,	,	PUNCT
bionys-641	501	7	190(2	190(2	NUM
bionys-641	501	8	)	)	PUNCT
bionys-641	501	9	,	,	PUNCT
bionys-641	501	10	272–285	272–285	NUM
bionys-641	501	11	.	.	PUNCT
bionys-641	502	1	https://doi.org/10.1016/j	https://doi.org/10.1016/j	NOUN
bionys-641	502	2	.	.	PUNCT
bionys-641	503	1	ajpath.2019.10.012	ajpath.2019.10.012	PROPN
bionys-641	503	2	kim	kim	PROPN
bionys-641	503	3	,	,	PUNCT
bionys-641	503	4	s.j	s.j	PROPN
bionys-641	503	5	.	.	PROPN
bionys-641	503	6	&	&	CCONJ
bionys-641	503	7	li	li	PROPN
bionys-641	503	8	,	,	PUNCT
bionys-641	503	9	j.	j.	PROPN
bionys-641	503	10	(	(	PUNCT
bionys-641	503	11	2013	2013	NUM
bionys-641	503	12	)	)	PUNCT
bionys-641	503	13	.	.	PUNCT
bionys-641	504	1	caspase	caspase	PROPN
bionys-641	504	2	blockade	blockade	NOUN
bionys-641	504	3	induces	induce	VERB
bionys-641	504	4	rip3	rip3	NOUN
bionys-641	504	5	-	-	PUNCT
bionys-641	504	6	mediated	mediate	VERB
bionys-641	504	7	programmed	program	VERB
bionys-641	504	8	necrosis	necrosis	NOUN
bionys-641	504	9	in	in	ADP
bionys-641	504	10	toll	toll	NOUN
bionys-641	504	11	-	-	PUNCT
bionys-641	504	12	like	like	ADJ
bionys-641	504	13	receptor	receptor	NOUN
bionys-641	504	14	-	-	PUNCT
bionys-641	504	15	activated	activate	VERB
bionys-641	504	16	microglia	microglia	NOUN
bionys-641	504	17	.	.	PUNCT
bionys-641	505	1	cell	cell	NOUN
bionys-641	505	2	death	death	NOUN
bionys-641	505	3	&	&	CCONJ
bionys-641	505	4	disease	disease	PROPN
bionys-641	505	5	,	,	PUNCT
bionys-641	505	6	4(7	4(7	NUM
bionys-641	505	7	)	)	PUNCT
bionys-641	505	8	,	,	PUNCT
bionys-641	505	9	e716	e716	PROPN
bionys-641	505	10	.	.	PUNCT
bionys-641	506	1	https://doi.org/10.1038/cddis.2013.238	https://doi.org/10.1038/cddis.2013.238	PROPN
bionys-641	506	2	kober	kober	PROPN
bionys-641	506	3	,	,	PUNCT
bionys-641	506	4	a.m.m	a.m.m	PROPN
bionys-641	506	5	.	.	PROPN
bionys-641	506	6	,	,	PUNCT
bionys-641	506	7	legewie	legewie	PROPN
bionys-641	506	8	,	,	PUNCT
bionys-641	506	9	s.	s.	PROPN
bionys-641	506	10	,	,	PUNCT
bionys-641	506	11	pforr	pforr	PROPN
bionys-641	506	12	,	,	PUNCT
bionys-641	506	13	c.	c.	NOUN
bionys-641	506	14	,	,	PUNCT
bionys-641	506	15	fricker	fricker	NOUN
bionys-641	506	16	,	,	PUNCT
bionys-641	506	17	n.	n.	NOUN
bionys-641	506	18	,	,	PUNCT
bionys-641	506	19	eils	eil	NOUN
bionys-641	506	20	,	,	PUNCT
bionys-641	506	21	r.	r.	PROPN
bionys-641	506	22	,	,	PUNCT
bionys-641	506	23	krammer	krammer	PROPN
bionys-641	506	24	,	,	PUNCT
bionys-641	506	25	p.h	p.h	PROPN
bionys-641	506	26	.	.	PROPN
bionys-641	506	27	,	,	PUNCT
bionys-641	506	28	&	&	CCONJ
bionys-641	506	29	lavrik	lavrik	PROPN
bionys-641	506	30	,	,	PUNCT
bionys-641	506	31	i.n	i.n	PROPN
bionys-641	506	32	.	.	PROPN
bionys-641	506	33	(	(	PUNCT
bionys-641	506	34	2011	2011	NUM
bionys-641	506	35	)	)	PUNCT
bionys-641	506	36	.	.	PUNCT
bionys-641	507	1	caspase-8	caspase-8	NOUN
bionys-641	507	2	activity	activity	NOUN
bionys-641	507	3	has	have	VERB
bionys-641	507	4	an	an	DET
bionys-641	507	5	essential	essential	ADJ
bionys-641	507	6	role	role	NOUN
bionys-641	507	7	in	in	ADP
bionys-641	507	8	cd95	cd95	PROPN
bionys-641	507	9	/	/	SYM
bionys-641	507	10	fas	fas	NOUN
bionys-641	507	11	-	-	PUNCT
bionys-641	507	12	mediated	mediate	VERB
bionys-641	507	13	mapk	mapk	NOUN
bionys-641	507	14	activation	activation	NOUN
bionys-641	507	15	.	.	PUNCT
bionys-641	508	1	cell	cell	NOUN
bionys-641	508	2	death	death	NOUN
bionys-641	508	3	&	&	CCONJ
bionys-641	508	4	disease	disease	PROPN
bionys-641	508	5	,	,	PUNCT
bionys-641	508	6	2(10	2(10	NOUN
bionys-641	508	7	)	)	PUNCT
bionys-641	508	8	,	,	PUNCT
bionys-641	508	9	e212	e212	PROPN
bionys-641	508	10	.	.	PUNCT
bionys-641	509	1	https://doi.org/10.1038/	https://doi.org/10.1038/	PROPN
bionys-641	509	2	cddis.2011.93	cddis.2011.93	PROPN
bionys-641	509	3	kroemer	kroemer	PROPN
bionys-641	509	4	,	,	PUNCT
bionys-641	509	5	g.	g.	PROPN
bionys-641	509	6	&	&	CCONJ
bionys-641	509	7	levine	levine	PROPN
bionys-641	509	8	,	,	PUNCT
bionys-641	509	9	b.	b.	PROPN
bionys-641	509	10	(	(	PUNCT
bionys-641	509	11	2008	2008	NUM
bionys-641	509	12	)	)	PUNCT
bionys-641	509	13	.	.	PUNCT
bionys-641	510	1	autophagic	autophagic	PROPN
bionys-641	510	2	cell	cell	NOUN
bionys-641	510	3	death	death	NOUN
bionys-641	510	4	:	:	PUNCT
bionys-641	510	5	the	the	DET
bionys-641	510	6	story	story	NOUN
bionys-641	510	7	of	of	ADP
bionys-641	510	8	a	a	DET
bionys-641	510	9	misnomer	misnomer	NOUN
bionys-641	510	10	.	.	PUNCT
bionys-641	511	1	nature	nature	NOUN
bionys-641	511	2	reviews	review	VERB
bionys-641	511	3	molecular	molecular	ADJ
bionys-641	511	4	cell	cell	NOUN
bionys-641	511	5	biology	biology	NOUN
bionys-641	511	6	,	,	PUNCT
bionys-641	511	7	9(12	9(12	NUM
bionys-641	511	8	)	)	PUNCT
bionys-641	511	9	,	,	PUNCT
bionys-641	511	10	1004–1010	1004–1010	NUM
bionys-641	511	11	.	.	PUNCT
bionys-641	512	1	https://	https://	PROPN
bionys-641	512	2	doi.org/10.1038/nrm2529	doi.org/10.1038/nrm2529	PROPN
bionys-641	512	3	li	li	PROPN
bionys-641	512	4	,	,	PUNCT
bionys-641	512	5	m.	m.	NOUN
bionys-641	512	6	,	,	PUNCT
bionys-641	512	7	carpio	carpio	NOUN
bionys-641	512	8	,	,	PUNCT
bionys-641	512	9	d.f	d.f	PROPN
bionys-641	512	10	.	.	PROPN
bionys-641	512	11	,	,	PUNCT
bionys-641	512	12	zheng	zheng	PROPN
bionys-641	512	13	,	,	PUNCT
bionys-641	512	14	y.	y.	PROPN
bionys-641	512	15	,	,	PUNCT
bionys-641	512	16	bruzzo	bruzzo	PROPN
bionys-641	512	17	,	,	PUNCT
bionys-641	512	18	p.	p.	NOUN
bionys-641	512	19	,	,	PUNCT
bionys-641	512	20	singh	singh	PROPN
bionys-641	512	21	,	,	PUNCT
bionys-641	512	22	v.	v.	PROPN
bionys-641	512	23	,	,	PUNCT
bionys-641	512	24	ouaaz	ouaaz	PROPN
bionys-641	512	25	,	,	PUNCT
bionys-641	512	26	f.	f.	PROPN
bionys-641	512	27	,	,	PUNCT
bionys-641	512	28	medzhitov	medzhitov	NOUN
bionys-641	512	29	,	,	PUNCT
bionys-641	512	30	r.m	r.m	PROPN
bionys-641	512	31	.	.	PROPN
bionys-641	512	32	,	,	PUNCT
bionys-641	512	33	&	&	CCONJ
bionys-641	512	34	beg	beg	PROPN
bionys-641	512	35	,	,	PUNCT
bionys-641	512	36	a.a	a.a	PROPN
bionys-641	512	37	.	.	PROPN
bionys-641	512	38	(	(	PUNCT
bionys-641	512	39	2001	2001	NUM
bionys-641	512	40	)	)	PUNCT
bionys-641	512	41	.	.	PUNCT
bionys-641	513	1	an	an	DET
bionys-641	513	2	essential	essential	ADJ
bionys-641	513	3	role	role	NOUN
bionys-641	513	4	of	of	ADP
bionys-641	513	5	the	the	DET
bionys-641	513	6	nf	nf	NOUN
bionys-641	513	7	-	-	PUNCT
bionys-641	513	8	κb	κb	NOUN
bionys-641	513	9	/	/	SYM
bionys-641	513	10	toll	toll	NOUN
bionys-641	513	11	-	-	PUNCT
bionys-641	513	12	like	like	ADJ
bionys-641	513	13	receptor	receptor	NOUN
bionys-641	513	14	pathway	pathway	NOUN
bionys-641	513	15	in	in	ADP
bionys-641	513	16	induction	induction	NOUN
bionys-641	513	17	of	of	ADP
bionys-641	513	18	inflammatory	inflammatory	ADJ
bionys-641	513	19	and	and	CCONJ
bionys-641	513	20	tissue	tissue	NOUN
bionys-641	513	21	-	-	PUNCT
bionys-641	513	22	repair	repair	NOUN
bionys-641	513	23	gene	gene	NOUN
bionys-641	513	24	expression	expression	NOUN
bionys-641	513	25	by	by	ADP
bionys-641	513	26	necrotic	necrotic	ADJ
bionys-641	513	27	cells	cell	NOUN
bionys-641	513	28	.	.	PUNCT
bionys-641	514	1	the	the	DET
bionys-641	514	2	journal	journal	NOUN
bionys-641	514	3	of	of	ADP
bionys-641	514	4	immunology	immunology	NOUN
bionys-641	514	5	,	,	PUNCT
bionys-641	514	6	166(12	166(12	NUM
bionys-641	514	7	)	)	PUNCT
bionys-641	514	8	,	,	PUNCT
bionys-641	514	9	7128–7135	7128–7135	NUM
bionys-641	514	10	.	.	PUNCT
bionys-641	515	1	https://doi.org/10.4049/jimmunol.166.12.7128	https://doi.org/10.4049/jimmunol.166.12.7128	PROPN
bionys-641	515	2	li	li	PROPN
bionys-641	515	3	,	,	PUNCT
bionys-641	515	4	x.	x.	PROPN
bionys-641	515	5	,	,	PUNCT
bionys-641	515	6	he	he	PRON
bionys-641	515	7	,	,	PUNCT
bionys-641	515	8	s.	s.	PROPN
bionys-641	515	9	,	,	PUNCT
bionys-641	515	10	&	&	CCONJ
bionys-641	515	11	ma	ma	PROPN
bionys-641	515	12	,	,	PUNCT
bionys-641	515	13	b.	b.	PROPN
bionys-641	515	14	(	(	PUNCT
bionys-641	515	15	2020	2020	NUM
bionys-641	515	16	)	)	PUNCT
bionys-641	515	17	.	.	PUNCT
bionys-641	516	1	autophagy	autophagy	ADJ
bionys-641	516	2	and	and	CCONJ
bionys-641	516	3	autophagy	autophagy	ADV
bionys-641	516	4	-	-	PUNCT
bionys-641	516	5	related	relate	VERB
bionys-641	516	6	proteins	protein	NOUN
bionys-641	516	7	in	in	ADP
bionys-641	516	8	cancer	cancer	NOUN
bionys-641	516	9	.	.	PUNCT
bionys-641	517	1	molecular	molecular	ADJ
bionys-641	517	2	cancer	cancer	NOUN
bionys-641	517	3	,	,	PUNCT
bionys-641	517	4	19(1	19(1	NUM
bionys-641	517	5	)	)	PUNCT
bionys-641	517	6	,	,	PUNCT
bionys-641	517	7	12	12	NUM
bionys-641	517	8	.	.	PUNCT
bionys-641	518	1	https://doi.org/10.1186/s12943020-1138-4	https://doi.org/10.1186/s12943020-1138-4	PROPN
bionys-641	518	2	li	li	PROPN
bionys-641	518	3	,	,	PUNCT
bionys-641	518	4	y.	y.	PROPN
bionys-641	518	5	,	,	PUNCT
bionys-641	518	6	sun	sun	PROPN
bionys-641	518	7	,	,	PUNCT
bionys-641	518	8	x.	x.	NOUN
bionys-641	518	9	,	,	PUNCT
bionys-641	518	10	&	&	CCONJ
bionys-641	518	11	dey	dey	PROPN
bionys-641	518	12	,	,	PUNCT
bionys-641	518	13	s.k	s.k	PROPN
bionys-641	518	14	.	.	PROPN
bionys-641	518	15	(	(	PUNCT
bionys-641	518	16	2015	2015	NUM
bionys-641	518	17	)	)	PUNCT
bionys-641	518	18	.	.	PUNCT
bionys-641	519	1	entosis	entosis	NOUN
bionys-641	519	2	allows	allow	VERB
bionys-641	519	3	timely	timely	ADJ
bionys-641	519	4	elimination	elimination	NOUN
bionys-641	519	5	of	of	ADP
bionys-641	519	6	the	the	DET
bionys-641	519	7	luminal	luminal	ADJ
bionys-641	519	8	epithelial	epithelial	ADJ
bionys-641	519	9	barrier	barrier	NOUN
bionys-641	519	10	for	for	ADP
bionys-641	519	11	embryo	embryo	NOUN
bionys-641	519	12	implantation	implantation	NOUN
bionys-641	519	13	.	.	PUNCT
bionys-641	520	1	cell	cell	NOUN
bionys-641	520	2	reports	report	NOUN
bionys-641	520	3	,	,	PUNCT
bionys-641	520	4	11(3	11(3	NUM
bionys-641	520	5	)	)	PUNCT
bionys-641	520	6	,	,	PUNCT
bionys-641	520	7	358	358	NUM
bionys-641	520	8	–	–	PUNCT
bionys-641	520	9	365	365	NUM
bionys-641	520	10	.	.	PUNCT
bionys-641	521	1	https://doi.org/10.1016/j.celrep.2015.03.035	https://doi.org/10.1016/j.celrep.2015.03.035	PROPN
bionys-641	521	2	liana	liana	NOUN
bionys-641	521	3	,	,	PUNCT
bionys-641	521	4	p.	p.	PROPN
bionys-641	521	5	,	,	PUNCT
bionys-641	521	6	liberty	liberty	PROPN
bionys-641	521	7	,	,	PUNCT
bionys-641	521	8	i.a	i.a	PROPN
bionys-641	521	9	.	.	PROPN
bionys-641	521	10	,	,	PUNCT
bionys-641	521	11	murti	murti	PROPN
bionys-641	521	12	,	,	PUNCT
bionys-641	521	13	k.	k.	PROPN
bionys-641	521	14	,	,	PUNCT
bionys-641	521	15	hafy	hafy	PROPN
bionys-641	521	16	,	,	PUNCT
bionys-641	521	17	z.	z.	PROPN
bionys-641	521	18	,	,	PUNCT
bionys-641	521	19	salim	salim	PROPN
bionys-641	521	20	,	,	PUNCT
bionys-641	521	21	e.m	e.m	PROPN
bionys-641	521	22	.	.	PROPN
bionys-641	521	23	,	,	PUNCT
bionys-641	521	24	zulkarnain	zulkarnain	PROPN
bionys-641	521	25	,	,	PUNCT
bionys-641	521	26	m.	m.	NOUN
bionys-641	521	27	,	,	PUNCT
bionys-641	521	28	&	&	CCONJ
bionys-641	521	29	umar	umar	PROPN
bionys-641	521	30	,	,	PUNCT
bionys-641	521	31	t.p	t.p	PROPN
bionys-641	521	32	.	.	PROPN
bionys-641	521	33	(	(	PUNCT
bionys-641	521	34	2022a	2022a	NUM
bionys-641	521	35	)	)	PUNCT
bionys-641	521	36	.	.	PUNCT
bionys-641	522	1	a	a	DET
bionys-641	522	2	systematic	systematic	ADJ
bionys-641	522	3	review	review	NOUN
bionys-641	522	4	on	on	ADP
bionys-641	522	5	neutrophil	neutrophil	ADJ
bionys-641	522	6	extracellular	extracellular	ADJ
bionys-641	522	7	traps	trap	NOUN
bionys-641	522	8	and	and	CCONJ
bionys-641	522	9	its	its	PRON
bionys-641	522	10	prognostication	prognostication	NOUN
bionys-641	522	11	role	role	NOUN
bionys-641	522	12	in	in	ADP
bionys-641	522	13	covid-19	covid-19	PROPN
bionys-641	522	14	patients	patient	NOUN
bionys-641	522	15	.	.	PUNCT
bionys-641	523	1	immunologic	immunologic	PROPN
bionys-641	523	2	research	research	PROPN
bionys-641	523	3	,	,	PUNCT
bionys-641	523	4	70(4	70(4	NUM
bionys-641	523	5	)	)	PUNCT
bionys-641	523	6	,	,	PUNCT
bionys-641	523	7	449–460	449–460	NUM
bionys-641	523	8	.	.	PUNCT
bionys-641	524	1	https://doi	https://doi	X
bionys-641	524	2	.	.	PUNCT
bionys-641	524	3	org/10.1007	org/10.1007	PROPN
bionys-641	524	4	/	/	SYM
bionys-641	524	5	s12026	s12026	PROPN
bionys-641	524	6	-	-	PUNCT
bionys-641	524	7	022	022	NUM
bionys-641	524	8	-	-	PUNCT
bionys-641	524	9	09293	09293	NUM
bionys-641	524	10	-	-	PUNCT
bionys-641	524	11	w	w	NOUN
bionys-641	524	12	liana	liana	NOUN
bionys-641	524	13	,	,	PUNCT
bionys-641	524	14	p.	p.	PROPN
bionys-641	524	15	,	,	PUNCT
bionys-641	524	16	murti	murti	PROPN
bionys-641	524	17	,	,	PUNCT
bionys-641	524	18	k.	k.	PROPN
bionys-641	524	19	,	,	PUNCT
bionys-641	524	20	hafy	hafy	PROPN
bionys-641	524	21	,	,	PUNCT
bionys-641	524	22	z.	z.	PROPN
bionys-641	524	23	,	,	PUNCT
bionys-641	524	24	liberty	liberty	PROPN
bionys-641	524	25	,	,	PUNCT
bionys-641	524	26	i.a	i.a	PROPN
bionys-641	524	27	.	.	PROPN
bionys-641	524	28	,	,	PUNCT
bionys-641	524	29	&	&	CCONJ
bionys-641	524	30	umar	umar	PROPN
bionys-641	524	31	,	,	PUNCT
bionys-641	524	32	t.p	t.p	PROPN
bionys-641	524	33	.	.	PROPN
bionys-641	524	34	(	(	PUNCT
bionys-641	524	35	2022b	2022b	NUM
bionys-641	524	36	)	)	PUNCT
bionys-641	524	37	.	.	PUNCT
bionys-641	525	1	neutrophil	neutrophil	ADJ
bionys-641	525	2	extracellular	extracellular	ADJ
bionys-641	525	3	traps	trap	NOUN
bionys-641	525	4	and	and	CCONJ
bionys-641	525	5	its	its	PRON
bionys-641	525	6	correlation	correlation	NOUN
bionys-641	525	7	with	with	ADP
bionys-641	525	8	several	several	ADJ
bionys-641	525	9	pathological	pathological	ADJ
bionys-641	525	10	conditions	condition	NOUN
bionys-641	525	11	:	:	PUNCT
bionys-641	525	12	prosperities	prosperity	NOUN
bionys-641	525	13	and	and	CCONJ
bionys-641	525	14	deleterious	deleterious	ADJ
bionys-641	525	15	implications	implication	NOUN
bionys-641	525	16	.	.	PUNCT
bionys-641	526	1	molecular	molecular	ADJ
bionys-641	526	2	and	and	CCONJ
bionys-641	526	3	cellular	cellular	ADJ
bionys-641	526	4	biomedical	biomedical	ADJ
bionys-641	526	5	sciences	science	NOUN
bionys-641	526	6	,	,	PUNCT
bionys-641	526	7	6(1	6(1	NUM
bionys-641	526	8	)	)	PUNCT
bionys-641	526	9	,	,	PUNCT
bionys-641	526	10	1–11	1–11	PROPN
bionys-641	526	11	.	.	PUNCT
bionys-641	527	1	https://doi.org/10.21705/mcbs	https://doi.org/10.21705/mcbs	PROPN
bionys-641	527	2	.	.	PUNCT
bionys-641	528	1	v6i1.224	v6i1.224	PROPN
bionys-641	529	1	liang	liang	PROPN
bionys-641	529	2	,	,	PUNCT
bionys-641	529	3	y.y	y.y	PROPN
bionys-641	529	4	.	.	PROPN
bionys-641	529	5	,	,	PUNCT
bionys-641	529	6	arnold	arnold	PROPN
bionys-641	529	7	,	,	PUNCT
bionys-641	529	8	t.	t.	PROPN
bionys-641	529	9	,	,	PUNCT
bionys-641	529	10	michlmayr	michlmayr	PROPN
bionys-641	529	11	,	,	PUNCT
bionys-641	529	12	a.	a.	NOUN
bionys-641	529	13	,	,	PUNCT
bionys-641	529	14	rainprecht	rainprecht	NOUN
bionys-641	529	15	,	,	PUNCT
bionys-641	529	16	d.	d.	PROPN
bionys-641	529	17	,	,	PUNCT
bionys-641	529	18	perticevic	perticevic	PROPN
bionys-641	529	19	,	,	PUNCT
bionys-641	529	20	b.	b.	PROPN
bionys-641	529	21	,	,	PUNCT
bionys-641	529	22	spittler	spittler	PROPN
bionys-641	529	23	,	,	PUNCT
bionys-641	529	24	a.	a.	NOUN
bionys-641	529	25	,	,	PUNCT
bionys-641	529	26	&	&	CCONJ
bionys-641	529	27	oehler	oehler	PROPN
bionys-641	529	28	,	,	PUNCT
bionys-641	529	29	r.	r.	PROPN
bionys-641	529	30	(	(	PUNCT
bionys-641	529	31	2014	2014	NUM
bionys-641	529	32	)	)	PUNCT
bionys-641	529	33	.	.	PUNCT
bionys-641	530	1	serum	serum	NOUN
bionys-641	530	2	-	-	PUNCT
bionys-641	530	3	dependent	dependent	ADJ
bionys-641	530	4	processing	processing	NOUN
bionys-641	530	5	of	of	ADP
bionys-641	530	6	late	late	ADJ
bionys-641	530	7	apoptotic	apoptotic	ADJ
bionys-641	530	8	cells	cell	NOUN
bionys-641	530	9	for	for	ADP
bionys-641	530	10	enhanced	enhanced	ADJ
bionys-641	530	11	efferocytosis	efferocytosis	NOUN
bionys-641	530	12	.	.	PUNCT
bionys-641	531	1	cell	cell	NOUN
bionys-641	531	2	death	death	NOUN
bionys-641	531	3	&	&	CCONJ
bionys-641	531	4	disease	disease	PROPN
bionys-641	531	5	,	,	PUNCT
bionys-641	531	6	5(5	5(5	NUM
bionys-641	531	7	)	)	PUNCT
bionys-641	531	8	,	,	PUNCT
bionys-641	531	9	e1264	e1264	NOUN
bionys-641	531	10	.	.	PUNCT
bionys-641	532	1	https://doi	https://doi	NOUN
bionys-641	532	2	.	.	PUNCT
bionys-641	532	3	org/10.1038	org/10.1038	PROPN
bionys-641	532	4	/	/	SYM
bionys-641	532	5	cddis.2014.210	cddis.2014.210	PROPN
bionys-641	532	6	lin	lin	PROPN
bionys-641	532	7	,	,	PUNCT
bionys-641	532	8	y.	y.	PROPN
bionys-641	532	9	,	,	PUNCT
bionys-641	532	10	epstein	epstein	PROPN
bionys-641	532	11	,	,	PUNCT
bionys-641	532	12	d.l	d.l	PROPN
bionys-641	532	13	.	.	PROPN
bionys-641	532	14	,	,	PUNCT
bionys-641	532	15	&	&	CCONJ
bionys-641	532	16	liton	liton	PROPN
bionys-641	532	17	,	,	PUNCT
bionys-641	532	18	p.b	p.b	PROPN
bionys-641	532	19	.	.	PROPN
bionys-641	532	20	(	(	PUNCT
bionys-641	532	21	2010	2010	NUM
bionys-641	532	22	)	)	PUNCT
bionys-641	532	23	.	.	PUNCT
bionys-641	533	1	intralysosomal	intralysosomal	ADJ
bionys-641	533	2	iron	iron	NOUN
bionys-641	533	3	induces	induce	VERB
bionys-641	533	4	lysosomal	lysosomal	ADJ
bionys-641	533	5	membrane	membrane	NOUN
bionys-641	533	6	permeabilization	permeabilization	NOUN
bionys-641	533	7	and	and	CCONJ
bionys-641	533	8	cathepsin	cathepsin	NOUN
bionys-641	533	9	d	d	PROPN
bionys-641	533	10	-	-	PUNCT
bionys-641	533	11	mediated	mediate	VERB
bionys-641	533	12	cell	cell	NOUN
bionys-641	533	13	death	death	NOUN
bionys-641	533	14	in	in	ADP
bionys-641	533	15	trabecular	trabecular	ADJ
bionys-641	533	16	meshwork	meshwork	ADJ
bionys-641	533	17	cells	cell	NOUN
bionys-641	533	18	exposed	expose	VERB
bionys-641	533	19	to	to	ADP
bionys-641	533	20	oxidative	oxidative	ADJ
bionys-641	533	21	stress	stress	NOUN
bionys-641	533	22	.	.	PUNCT
bionys-641	534	1	investigative	investigative	ADJ
bionys-641	534	2	ophthalmology	ophthalmology	NOUN
bionys-641	534	3	&	&	CCONJ
bionys-641	534	4	visual	visual	ADJ
bionys-641	534	5	science	science	NOUN
bionys-641	534	6	,	,	PUNCT
bionys-641	534	7	51(12	51(12	NUM
bionys-641	534	8	)	)	PUNCT
bionys-641	534	9	,	,	PUNCT
bionys-641	534	10	6483–6495	6483–6495	NUM
bionys-641	534	11	.	.	PUNCT
bionys-641	535	1	https://doi	https://doi	NOUN
bionys-641	535	2	.	.	PUNCT
bionys-641	535	3	org/10.1167	org/10.1167	ADJ
bionys-641	535	4	/	/	SYM
bionys-641	535	5	iovs.10	iovs.10	NOUN
bionys-641	535	6	-	-	PUNCT
bionys-641	535	7	5410	5410	NUM
bionys-641	535	8	liu	liu	PROPN
bionys-641	535	9	,	,	PUNCT
bionys-641	535	10	j.	j.	PROPN
bionys-641	535	11	,	,	PUNCT
bionys-641	535	12	kuang	kuang	PROPN
bionys-641	535	13	,	,	PUNCT
bionys-641	535	14	f.	f.	PROPN
bionys-641	535	15	,	,	PUNCT
bionys-641	535	16	kang	kang	PROPN
bionys-641	535	17	,	,	PUNCT
bionys-641	535	18	r.	r.	PROPN
bionys-641	535	19	,	,	PUNCT
bionys-641	535	20	&	&	CCONJ
bionys-641	535	21	tang	tang	PROPN
bionys-641	535	22	,	,	PUNCT
bionys-641	535	23	d.	d.	PROPN
bionys-641	535	24	(	(	PUNCT
bionys-641	535	25	2019	2019	NUM
bionys-641	535	26	)	)	PUNCT
bionys-641	535	27	.	.	PUNCT
bionys-641	536	1	alkaliptosis	alkaliptosis	ADJ
bionys-641	536	2	:	:	PUNCT
bionys-641	536	3	a	a	DET
bionys-641	536	4	new	new	ADJ
bionys-641	536	5	weapon	weapon	NOUN
bionys-641	536	6	for	for	ADP
bionys-641	536	7	cancer	cancer	NOUN
bionys-641	536	8	therapy	therapy	NOUN
bionys-641	536	9	.	.	PUNCT
bionys-641	537	1	cancer	cancer	NOUN
bionys-641	537	2	gene	gene	NOUN
bionys-641	537	3	therapy	therapy	NOUN
bionys-641	537	4	,	,	PUNCT
bionys-641	537	5	27	27	NUM
bionys-641	537	6	,	,	PUNCT
bionys-641	537	7	1–3	1–3	NOUN
bionys-641	537	8	.	.	PUNCT
bionys-641	538	1	https://doi	https://doi	NOUN
bionys-641	538	2	.	.	PUNCT
bionys-641	539	1	org/10.1038	org/10.1038	PROPN
bionys-641	539	2	/	/	SYM
bionys-641	539	3	s41417	s41417	PROPN
bionys-641	539	4	-	-	PUNCT
bionys-641	539	5	019	019	NUM
bionys-641	539	6	-	-	PUNCT
bionys-641	539	7	0134	0134	NUM
bionys-641	539	8	-	-	SYM
bionys-641	539	9	6	6	NUM
bionys-641	539	10	liu	liu	PROPN
bionys-641	539	11	,	,	PUNCT
bionys-641	539	12	y.	y.	PROPN
bionys-641	539	13	,	,	PUNCT
bionys-641	539	14	li	li	PROPN
bionys-641	539	15	,	,	PUNCT
bionys-641	539	16	z.	z.	PROPN
bionys-641	539	17	,	,	PUNCT
bionys-641	539	18	song	song	NOUN
bionys-641	539	19	,	,	PUNCT
bionys-641	539	20	t.	t.	PROPN
bionys-641	539	21	,	,	PUNCT
bionys-641	539	22	xue	xue	PROPN
bionys-641	539	23	,	,	PUNCT
bionys-641	539	24	z.	z.	PROPN
bionys-641	539	25	,	,	PUNCT
bionys-641	539	26	&	&	CCONJ
bionys-641	539	27	zhang	zhang	PROPN
bionys-641	539	28	,	,	PUNCT
bionys-641	539	29	z.	z.	PROPN
bionys-641	539	30	(	(	PUNCT
bionys-641	539	31	2013	2013	NUM
bionys-641	539	32	)	)	PUNCT
bionys-641	539	33	.	.	PUNCT
bionys-641	540	1	mechanisms	mechanism	NOUN
bionys-641	540	2	of	of	ADP
bionys-641	540	3	anti	anti	ADJ
bionys-641	540	4	-	-	ADJ
bionys-641	540	5	leukemic	leukemic	ADJ
bionys-641	540	6	activity	activity	NOUN
bionys-641	540	7	of	of	ADP
bionys-641	540	8	the	the	DET
bionys-641	540	9	bcl-2	bcl-2	PUNCT
bionys-641	540	10	homology	homology	NOUN
bionys-641	540	11	domain-3	domain-3	NUM
bionys-641	540	12	mimetic	mimetic	ADJ
bionys-641	540	13	s1	s1	NOUN
bionys-641	540	14	.	.	PUNCT
bionys-641	540	15	biomedicine	biomedicine	NOUN
bionys-641	540	16	&	&	CCONJ
bionys-641	540	17	pharmacotherapy	pharmacotherapy	NOUN
bionys-641	540	18	,	,	PUNCT
bionys-641	540	19	67(7	67(7	NUM
bionys-641	540	20	)	)	PUNCT
bionys-641	540	21	,	,	PUNCT
bionys-641	540	22	583–591	583–591	NUM
bionys-641	540	23	.	.	PUNCT
bionys-641	541	1	https://doi	https://doi	X
bionys-641	541	2	.	.	PUNCT
bionys-641	541	3	org/10.1016	org/10.1016	PROPN
bionys-641	541	4	/	/	SYM
bionys-641	541	5	j.biopha.2013.04.010	j.biopha.2013.04.010	PROPN
bionys-641	541	6	loftus	loftus	PROPN
bionys-641	541	7	,	,	PUNCT
bionys-641	541	8	l.v	l.v	PROPN
bionys-641	541	9	,	,	PUNCT
bionys-641	541	10	amend	amend	PROPN
bionys-641	541	11	,	,	PUNCT
bionys-641	541	12	s.r	s.r	PROPN
bionys-641	541	13	.	.	PROPN
bionys-641	541	14	,	,	PUNCT
bionys-641	541	15	&	&	CCONJ
bionys-641	541	16	pienta	pienta	PROPN
bionys-641	541	17	,	,	PUNCT
bionys-641	541	18	k.j	k.j	PROPN
bionys-641	541	19	.	.	PROPN
bionys-641	541	20	(	(	PUNCT
bionys-641	541	21	2022	2022	NUM
bionys-641	541	22	)	)	PUNCT
bionys-641	541	23	.	.	PUNCT
bionys-641	542	1	interplay	interplay	NOUN
bionys-641	542	2	between	between	ADP
bionys-641	542	3	cell	cell	NOUN
bionys-641	542	4	death	death	NOUN
bionys-641	542	5	and	and	CCONJ
bionys-641	542	6	cell	cell	NOUN
bionys-641	542	7	proliferation	proliferation	NOUN
bionys-641	542	8	reveals	reveal	VERB
bionys-641	542	9	new	new	ADJ
bionys-641	542	10	strategies	strategy	NOUN
bionys-641	542	11	for	for	ADP
bionys-641	542	12	cancer	cancer	NOUN
bionys-641	542	13	therapy	therapy	NOUN
bionys-641	542	14	.	.	PUNCT
bionys-641	543	1	international	international	ADJ
bionys-641	543	2	journal	journal	NOUN
bionys-641	543	3	of	of	ADP
bionys-641	543	4	molecular	molecular	ADJ
bionys-641	543	5	sciences	science	NOUN
bionys-641	543	6	,	,	PUNCT
bionys-641	543	7	23(9	23(9	NUM
bionys-641	543	8	)	)	PUNCT
bionys-641	543	9	,	,	PUNCT
bionys-641	543	10	4723	4723	NUM
bionys-641	543	11	.	.	PUNCT
bionys-641	544	1	https://doi.org/10.3390/ijms23094723	https://doi.org/10.3390/ijms23094723	PROPN
bionys-641	544	2	biologica	biologica	PROPN
bionys-641	544	3	nyssana	nyssana	PROPN
bionys-641	544	4	●	●	PUNCT
bionys-641	544	5	16	16	NUM
bionys-641	544	6	(	(	PUNCT
bionys-641	544	7	2	2	NUM
bionys-641	544	8	)	)	PUNCT
bionys-641	544	9	december	december	PROPN
bionys-641	544	10	2025	2025	NUM
bionys-641	544	11	:	:	PUNCT
bionys-641	544	12	liana	liana	NOUN
bionys-641	544	13	et	et	PROPN
bionys-641	544	14	al	al	PROPN
bionys-641	544	15	.	.	PUNCT
bionys-641	545	1	●	●	PUNCT
bionys-641	545	2	cell	cell	NOUN
bionys-641	545	3	deaths	death	NOUN
bionys-641	545	4	and	and	CCONJ
bionys-641	545	5	their	their	PRON
bionys-641	545	6	associated	associate	VERB
bionys-641	545	7	mechanisms	mechanism	NOUN
bionys-641	545	8	biologica	biologica	PROPN
bionys-641	545	9	nyssana	nyssana	PROPN
bionys-641	545	10	●	●	PUNCT
bionys-641	545	11	16	16	NUM
bionys-641	545	12	(	(	PUNCT
bionys-641	545	13	2	2	NUM
bionys-641	545	14	)	)	PUNCT
bionys-641	545	15	december	december	PROPN
bionys-641	545	16	2025	2025	NUM
bionys-641	545	17	:	:	PUNCT
bionys-641	545	18	liana	liana	NOUN
bionys-641	545	19	et	et	PROPN
bionys-641	545	20	al	al	PROPN
bionys-641	545	21	.	.	PUNCT
bionys-641	546	1	●	●	PUNCT
bionys-641	546	2	cell	cell	NOUN
bionys-641	546	3	deaths	death	NOUN
bionys-641	546	4	and	and	CCONJ
bionys-641	546	5	their	their	PRON
bionys-641	546	6	associated	associate	VERB
bionys-641	546	7	mechanisms	mechanism	NOUN
bionys-641	546	8	ludwig	ludwig	PROPN
bionys-641	546	9	,	,	PUNCT
bionys-641	546	10	l.m	l.m	PROPN
bionys-641	546	11	.	.	PROPN
bionys-641	546	12	,	,	PUNCT
bionys-641	546	13	hawley	hawley	PROPN
bionys-641	546	14	,	,	PUNCT
bionys-641	546	15	k.m	k.m	PROPN
bionys-641	546	16	.	.	PROPN
bionys-641	546	17	,	,	PUNCT
bionys-641	546	18	banks	bank	NOUN
bionys-641	546	19	,	,	PUNCT
bionys-641	546	20	d.b	d.b	PROPN
bionys-641	546	21	.	.	PROPN
bionys-641	546	22	,	,	PUNCT
bionys-641	546	23	thomas	thomas	PROPN
bionys-641	546	24	-	-	PUNCT
bionys-641	546	25	toth	toth	PROPN
bionys-641	546	26	,	,	PUNCT
bionys-641	546	27	a.t	a.t	PROPN
bionys-641	546	28	.	.	PROPN
bionys-641	546	29	,	,	PUNCT
bionys-641	546	30	blazar	blazar	PROPN
bionys-641	546	31	,	,	PUNCT
bionys-641	546	32	b.r	b.r	PROPN
bionys-641	546	33	.	.	PROPN
bionys-641	546	34	,	,	PUNCT
bionys-641	546	35	mcnerney	mcnerney	PROPN
bionys-641	546	36	,	,	PUNCT
bionys-641	546	37	m.e	m.e	PROPN
bionys-641	546	38	.	.	PROPN
bionys-641	546	39	,	,	PUNCT
bionys-641	546	40	leverson	leverson	PROPN
bionys-641	546	41	,	,	PUNCT
bionys-641	546	42	j.d	j.d	PROPN
bionys-641	546	43	.	.	PROPN
bionys-641	546	44	,	,	PUNCT
bionys-641	546	45	&	&	CCONJ
bionys-641	546	46	labelle	labelle	PROPN
bionys-641	546	47	,	,	PUNCT
bionys-641	546	48	j.l	j.l	PROPN
bionys-641	546	49	.	.	PROPN
bionys-641	546	50	(	(	PUNCT
bionys-641	546	51	2021	2021	NUM
bionys-641	546	52	)	)	PUNCT
bionys-641	546	53	.	.	PUNCT
bionys-641	547	1	venetoclax	venetoclax	PROPN
bionys-641	547	2	imparts	impart	VERB
bionys-641	547	3	distinct	distinct	ADJ
bionys-641	547	4	cell	cell	NOUN
bionys-641	547	5	death	death	NOUN
bionys-641	547	6	sensitivity	sensitivity	NOUN
bionys-641	547	7	and	and	CCONJ
bionys-641	547	8	adaptivity	adaptivity	NOUN
bionys-641	547	9	patterns	pattern	NOUN
bionys-641	547	10	in	in	ADP
bionys-641	547	11	t	t	NOUN
bionys-641	547	12	cells	cell	NOUN
bionys-641	547	13	.	.	PUNCT
bionys-641	548	1	cell	cell	NOUN
bionys-641	548	2	death	death	NOUN
bionys-641	548	3	&	&	CCONJ
bionys-641	548	4	disease	disease	PROPN
bionys-641	548	5	,	,	PUNCT
bionys-641	548	6	12(11	12(11	NUM
bionys-641	548	7	)	)	PUNCT
bionys-641	548	8	,	,	PUNCT
bionys-641	548	9	1005	1005	NUM
bionys-641	548	10	.	.	PUNCT
bionys-641	549	1	https://doi.org/10.1038/s41419-02104285-4	https://doi.org/10.1038/s41419-02104285-4	PROPN
bionys-641	549	2	mansoori	mansoori	PROPN
bionys-641	549	3	,	,	PUNCT
bionys-641	549	4	b.	b.	PROPN
bionys-641	549	5	,	,	PUNCT
bionys-641	549	6	mohammadi	mohammadi	NOUN
bionys-641	549	7	,	,	PUNCT
bionys-641	549	8	a.	a.	NOUN
bionys-641	549	9	,	,	PUNCT
bionys-641	549	10	davudian	davudian	PROPN
bionys-641	549	11	,	,	PUNCT
bionys-641	549	12	s.	s.	PROPN
bionys-641	549	13	,	,	PUNCT
bionys-641	549	14	shirjang	shirjang	PROPN
bionys-641	549	15	,	,	PUNCT
bionys-641	549	16	s.	s.	PROPN
bionys-641	549	17	,	,	PUNCT
bionys-641	549	18	&	&	CCONJ
bionys-641	549	19	baradaran	baradaran	PROPN
bionys-641	549	20	,	,	PUNCT
bionys-641	549	21	b.	b.	PROPN
bionys-641	549	22	(	(	PUNCT
bionys-641	549	23	2017	2017	NUM
bionys-641	549	24	)	)	PUNCT
bionys-641	549	25	.	.	PUNCT
bionys-641	550	1	the	the	DET
bionys-641	550	2	different	different	ADJ
bionys-641	550	3	mechanisms	mechanism	NOUN
bionys-641	550	4	of	of	ADP
bionys-641	550	5	cancer	cancer	NOUN
bionys-641	550	6	drug	drug	NOUN
bionys-641	550	7	resistance	resistance	NOUN
bionys-641	550	8	:	:	PUNCT
bionys-641	550	9	a	a	DET
bionys-641	550	10	brief	brief	ADJ
bionys-641	550	11	review	review	NOUN
bionys-641	550	12	.	.	PUNCT
bionys-641	551	1	advanced	advanced	ADJ
bionys-641	551	2	pharmaceutical	pharmaceutical	ADJ
bionys-641	551	3	bulletin	bulletin	NOUN
bionys-641	551	4	,	,	PUNCT
bionys-641	551	5	7(3	7(3	NUM
bionys-641	551	6	)	)	PUNCT
bionys-641	551	7	,	,	PUNCT
bionys-641	551	8	339–348	339–348	NUM
bionys-641	551	9	.	.	PUNCT
bionys-641	552	1	https://doi.org/10.15171/apb.2017.041	https://doi.org/10.15171/apb.2017.041	NOUN
bionys-641	552	2	martins	martin	NOUN
bionys-641	552	3	,	,	PUNCT
bionys-641	552	4	i.	i.	PROPN
bionys-641	552	5	,	,	PUNCT
bionys-641	552	6	raza	raza	PROPN
bionys-641	552	7	,	,	PUNCT
bionys-641	552	8	s.q	s.q	PROPN
bionys-641	552	9	.	.	PROPN
bionys-641	552	10	,	,	PUNCT
bionys-641	552	11	voisin	voisin	PROPN
bionys-641	552	12	,	,	PUNCT
bionys-641	552	13	l.	l.	PROPN
bionys-641	552	14	,	,	PUNCT
bionys-641	552	15	dakhli	dakhli	PROPN
bionys-641	552	16	,	,	PUNCT
bionys-641	552	17	h.	h.	PROPN
bionys-641	552	18	,	,	PUNCT
bionys-641	552	19	law	law	PROPN
bionys-641	552	20	,	,	PUNCT
bionys-641	552	21	f.	f.	PROPN
bionys-641	552	22	,	,	PUNCT
bionys-641	552	23	de	de	PROPN
bionys-641	552	24	jong	jong	PROPN
bionys-641	552	25	,	,	PUNCT
bionys-641	552	26	d.	d.	PROPN
bionys-641	552	27	,	,	PUNCT
bionys-641	552	28	allouch	allouch	PROPN
bionys-641	552	29	,	,	PUNCT
bionys-641	552	30	a.	a.	PROPN
bionys-641	552	31	,	,	PUNCT
bionys-641	552	32	thoreau	thoreau	PROPN
bionys-641	552	33	,	,	PUNCT
bionys-641	552	34	m.	m.	NOUN
bionys-641	552	35	,	,	PUNCT
bionys-641	552	36	brenner	brenner	PROPN
bionys-641	552	37	,	,	PUNCT
bionys-641	552	38	c.	c.	PROPN
bionys-641	552	39	,	,	PUNCT
bionys-641	552	40	deutsch	deutsch	PROPN
bionys-641	552	41	,	,	PUNCT
bionys-641	552	42	e.	e.	PROPN
bionys-641	552	43	,	,	PUNCT
bionys-641	552	44	&	&	CCONJ
bionys-641	552	45	perfettini	perfettini	ADJ
bionys-641	552	46	,	,	PUNCT
bionys-641	552	47	j.-l	j.-l	PROPN
bionys-641	552	48	.	.	PUNCT
bionys-641	553	1	(	(	PUNCT
bionys-641	553	2	2017	2017	NUM
bionys-641	553	3	)	)	PUNCT
bionys-641	553	4	.	.	PUNCT
bionys-641	554	1	entosis	entosis	NOUN
bionys-641	554	2	:	:	PUNCT
bionys-641	554	3	the	the	DET
bionys-641	554	4	emerging	emerge	VERB
bionys-641	554	5	face	face	NOUN
bionys-641	554	6	of	of	ADP
bionys-641	554	7	non	non	ADJ
bionys-641	554	8	-	-	ADJ
bionys-641	554	9	cellautonomous	cellautonomous	ADJ
bionys-641	554	10	type	type	NOUN
bionys-641	554	11	iv	iv	NUM
bionys-641	554	12	programmed	program	VERB
bionys-641	554	13	death	death	NOUN
bionys-641	554	14	.	.	PUNCT
bionys-641	555	1	biomedical	biomedical	ADJ
bionys-641	555	2	journal	journal	PROPN
bionys-641	555	3	,	,	PUNCT
bionys-641	555	4	40(3	40(3	NUM
bionys-641	555	5	)	)	PUNCT
bionys-641	555	6	,	,	PUNCT
bionys-641	555	7	133–140	133–140	NUM
bionys-641	555	8	.	.	PUNCT
bionys-641	556	1	https://doi.org/10.1016/j	https://doi.org/10.1016/j	NOUN
bionys-641	556	2	.	.	PUNCT
bionys-641	557	1	bj.2017.05.001	bj.2017.05.001	NOUN
bionys-641	557	2	miao	miao	NOUN
bionys-641	557	3	,	,	PUNCT
bionys-641	557	4	y.	y.	PROPN
bionys-641	557	5	,	,	PUNCT
bionys-641	557	6	yin	yin	PROPN
bionys-641	557	7	,	,	PUNCT
bionys-641	557	8	q.	q.	PROPN
bionys-641	557	9	,	,	PUNCT
bionys-641	557	10	ping	ping	PROPN
bionys-641	557	11	,	,	PUNCT
bionys-641	557	12	l.	l.	PROPN
bionys-641	557	13	,	,	PUNCT
bionys-641	557	14	sheng	sheng	PROPN
bionys-641	557	15	,	,	PUNCT
bionys-641	557	16	h.	h.	PROPN
bionys-641	557	17	,	,	PUNCT
bionys-641	557	18	chang	chang	PROPN
bionys-641	557	19	,	,	PUNCT
bionys-641	557	20	j.	j.	PROPN
bionys-641	557	21	,	,	PUNCT
bionys-641	557	22	li	li	PROPN
bionys-641	557	23	,	,	PUNCT
bionys-641	557	24	w.	w.	PROPN
bionys-641	557	25	,	,	PUNCT
bionys-641	557	26	&	&	CCONJ
bionys-641	557	27	lv	lv	PROPN
bionys-641	557	28	,	,	PUNCT
bionys-641	557	29	s.	s.	PROPN
bionys-641	557	30	(	(	PUNCT
bionys-641	557	31	2023	2023	NUM
bionys-641	557	32	)	)	PUNCT
bionys-641	557	33	.	.	PUNCT
bionys-641	558	1	pseudolaric	pseudolaric	ADJ
bionys-641	558	2	acid	acid	PROPN
bionys-641	558	3	b	b	PROPN
bionys-641	558	4	triggers	trigger	NOUN
bionys-641	558	5	ferritinophagy	ferritinophagy	ADJ
bionys-641	558	6	and	and	CCONJ
bionys-641	558	7	ferroptosis	ferroptosis	NOUN
bionys-641	558	8	via	via	ADP
bionys-641	558	9	upregulating	upregulating	NOUN
bionys-641	558	10	ncoa4	ncoa4	NOUN
bionys-641	558	11	in	in	ADP
bionys-641	558	12	lung	lung	NOUN
bionys-641	558	13	adenocarcinoma	adenocarcinoma	NOUN
bionys-641	558	14	cells	cell	NOUN
bionys-641	558	15	.	.	PUNCT
bionys-641	559	1	journal	journal	NOUN
bionys-641	559	2	of	of	ADP
bionys-641	559	3	cancer	cancer	NOUN
bionys-641	559	4	research	research	NOUN
bionys-641	559	5	and	and	CCONJ
bionys-641	559	6	therapeutics	therapeutic	NOUN
bionys-641	559	7	,	,	PUNCT
bionys-641	559	8	19(6	19(6	NUM
bionys-641	559	9	)	)	PUNCT
bionys-641	559	10	,	,	PUNCT
bionys-641	559	11	1646	1646	NUM
bionys-641	559	12	–	–	PUNCT
bionys-641	559	13	1653	1653	NUM
bionys-641	559	14	.	.	PUNCT
bionys-641	560	1	https://doi.org/10.4103/jcrt.jcrt_806_23	https://doi.org/10.4103/jcrt.jcrt_806_23	NOUN
bionys-641	560	2	min	min	PROPN
bionys-641	560	3	,	,	PUNCT
bionys-641	560	4	k.-j	k.-j	PROPN
bionys-641	560	5	.	.	PROPN
bionys-641	560	6	,	,	PUNCT
bionys-641	560	7	&	&	CCONJ
bionys-641	560	8	kwon	kwon	PROPN
bionys-641	560	9	,	,	PUNCT
bionys-641	560	10	t.k	t.k	PROPN
bionys-641	560	11	.	.	PROPN
bionys-641	560	12	(	(	PUNCT
bionys-641	560	13	2020	2020	NUM
bionys-641	560	14	)	)	PUNCT
bionys-641	560	15	.	.	PUNCT
bionys-641	561	1	induction	induction	NOUN
bionys-641	561	2	of	of	ADP
bionys-641	561	3	lysosomal	lysosomal	ADJ
bionys-641	561	4	membrane	membrane	NOUN
bionys-641	561	5	permeabilization	permeabilization	NOUN
bionys-641	561	6	is	be	AUX
bionys-641	561	7	a	a	DET
bionys-641	561	8	major	major	ADJ
bionys-641	561	9	event	event	NOUN
bionys-641	561	10	of	of	ADP
bionys-641	561	11	fty720	fty720	PROPN
bionys-641	561	12	-	-	PUNCT
bionys-641	561	13	mediated	mediate	VERB
bionys-641	561	14	non	non	ADJ
bionys-641	561	15	-	-	ADJ
bionys-641	561	16	apoptotic	apoptotic	ADJ
bionys-641	561	17	cell	cell	NOUN
bionys-641	561	18	death	death	NOUN
bionys-641	561	19	in	in	ADP
bionys-641	561	20	human	human	ADJ
bionys-641	561	21	glioma	glioma	NOUN
bionys-641	561	22	cells	cell	NOUN
bionys-641	561	23	.	.	PUNCT
bionys-641	562	1	cancers	cancer	NOUN
bionys-641	562	2	,	,	PUNCT
bionys-641	562	3	12(11	12(11	NUM
bionys-641	562	4	)	)	PUNCT
bionys-641	562	5	,	,	PUNCT
bionys-641	562	6	3388	3388	NUM
bionys-641	562	7	.	.	PUNCT
bionys-641	563	1	https://doi.org/10.3390/cancers12113388	https://doi.org/10.3390/cancers12113388	NOUN
bionys-641	563	2	mirzayans	mirzayan	NOUN
bionys-641	563	3	,	,	PUNCT
bionys-641	563	4	r.	r.	PROPN
bionys-641	563	5	(	(	PUNCT
bionys-641	563	6	2024	2024	NUM
bionys-641	563	7	)	)	PUNCT
bionys-641	563	8	.	.	PUNCT
bionys-641	564	1	when	when	SCONJ
bionys-641	564	2	therapy	therapy	NOUN
bionys-641	564	3	-	-	PUNCT
bionys-641	564	4	induced	induce	VERB
bionys-641	564	5	cancer	cancer	NOUN
bionys-641	564	6	cell	cell	NOUN
bionys-641	564	7	apoptosis	apoptosis	NOUN
bionys-641	564	8	fuels	fuel	NOUN
bionys-641	564	9	tumor	tumor	NOUN
bionys-641	564	10	relapse	relapse	NOUN
bionys-641	564	11	.	.	PUNCT
bionys-641	565	1	onco	onco	PROPN
bionys-641	565	2	,	,	PUNCT
bionys-641	565	3	4(1	4(1	PROPN
bionys-641	565	4	)	)	PUNCT
bionys-641	565	5	,	,	PUNCT
bionys-641	565	6	37–45	37–45	NUM
bionys-641	565	7	.	.	PUNCT
bionys-641	565	8	https://doi.org/10.3390/onco4010003	https://doi.org/10.3390/onco4010003	PROPN
bionys-641	565	9	moriwaki	moriwaki	PROPN
bionys-641	565	10	,	,	PUNCT
bionys-641	565	11	k.	k.	PROPN
bionys-641	565	12	,	,	PUNCT
bionys-641	565	13	bertin	bertin	PROPN
bionys-641	565	14	,	,	PUNCT
bionys-641	565	15	j.	j.	PROPN
bionys-641	565	16	,	,	PUNCT
bionys-641	565	17	gough	gough	PROPN
bionys-641	565	18	,	,	PUNCT
bionys-641	565	19	p.j	p.j	PROPN
bionys-641	565	20	.	.	PROPN
bionys-641	565	21	,	,	PUNCT
bionys-641	565	22	orlowski	orlowski	PROPN
bionys-641	565	23	,	,	PUNCT
bionys-641	565	24	g.m	g.m	PROPN
bionys-641	565	25	.	.	PROPN
bionys-641	565	26	,	,	PUNCT
bionys-641	565	27	&	&	CCONJ
bionys-641	565	28	chan	chan	PROPN
bionys-641	565	29	,	,	PUNCT
bionys-641	565	30	f.k.m	f.k.m	PROPN
bionys-641	565	31	.	.	PROPN
bionys-641	565	32	(	(	PUNCT
bionys-641	565	33	2015	2015	NUM
bionys-641	565	34	)	)	PUNCT
bionys-641	565	35	.	.	PUNCT
bionys-641	566	1	differential	differential	ADJ
bionys-641	566	2	roles	role	NOUN
bionys-641	566	3	of	of	ADP
bionys-641	566	4	ripk1	ripk1	NOUN
bionys-641	566	5	and	and	CCONJ
bionys-641	566	6	ripk3	ripk3	NOUN
bionys-641	566	7	in	in	ADP
bionys-641	566	8	tnf	tnf	PROPN
bionys-641	566	9	-	-	PUNCT
bionys-641	566	10	induced	induce	VERB
bionys-641	566	11	necroptosis	necroptosis	NOUN
bionys-641	566	12	and	and	CCONJ
bionys-641	566	13	chemotherapeutic	chemotherapeutic	ADJ
bionys-641	566	14	agent	agent	NOUN
bionys-641	566	15	-	-	PUNCT
bionys-641	566	16	induced	induce	VERB
bionys-641	566	17	cell	cell	NOUN
bionys-641	566	18	death	death	NOUN
bionys-641	566	19	.	.	PUNCT
bionys-641	567	1	cell	cell	NOUN
bionys-641	567	2	death	death	NOUN
bionys-641	567	3	&	&	CCONJ
bionys-641	567	4	disease	disease	PROPN
bionys-641	567	5	,	,	PUNCT
bionys-641	567	6	6(2	6(2	NUM
bionys-641	567	7	)	)	PUNCT
bionys-641	567	8	,	,	PUNCT
bionys-641	567	9	e1636	e1636	NOUN
bionys-641	567	10	.	.	PUNCT
bionys-641	568	1	https://doi	https://doi	PROPN
bionys-641	568	2	.	.	PUNCT
bionys-641	568	3	org/10.1038	org/10.1038	PROPN
bionys-641	568	4	/	/	SYM
bionys-641	568	5	cddis.2015.16	cddis.2015.16	PROPN
bionys-641	568	6	murphy	murphy	PROPN
bionys-641	568	7	,	,	PUNCT
bionys-641	568	8	j.m	j.m	PROPN
bionys-641	568	9	.	.	PROPN
bionys-641	568	10	,	,	PUNCT
bionys-641	568	11	czabotar	czabotar	NOUN
bionys-641	568	12	,	,	PUNCT
bionys-641	568	13	p.e	p.e	PROPN
bionys-641	568	14	.	.	PROPN
bionys-641	568	15	,	,	PUNCT
bionys-641	568	16	hildebrand	hildebrand	PROPN
bionys-641	568	17	,	,	PUNCT
bionys-641	568	18	j.m	j.m	PROPN
bionys-641	568	19	.	.	PROPN
bionys-641	568	20	,	,	PUNCT
bionys-641	568	21	lucet	lucet	PROPN
bionys-641	568	22	,	,	PUNCT
bionys-641	568	23	i.s	i.s	PROPN
bionys-641	568	24	.	.	PROPN
bionys-641	568	25	,	,	PUNCT
bionys-641	568	26	zhang	zhang	PROPN
bionys-641	568	27	,	,	PUNCT
bionys-641	568	28	j.-g	j.-g	PROPN
bionys-641	568	29	.	.	PROPN
bionys-641	568	30	,	,	PUNCT
bionys-641	568	31	alvarez	alvarez	PROPN
bionys-641	568	32	-	-	PUNCT
bionys-641	568	33	diaz	diaz	PROPN
bionys-641	568	34	,	,	PUNCT
bionys-641	568	35	s.	s.	PROPN
bionys-641	568	36	,	,	PUNCT
bionys-641	568	37	lewis	lewis	PROPN
bionys-641	568	38	,	,	PUNCT
bionys-641	568	39	r.	r.	PROPN
bionys-641	568	40	,	,	PUNCT
bionys-641	568	41	lalaoui	lalaoui	NOUN
bionys-641	568	42	,	,	PUNCT
bionys-641	568	43	n.	n.	NOUN
bionys-641	568	44	,	,	PUNCT
bionys-641	568	45	metcalf	metcalf	PROPN
bionys-641	568	46	,	,	PUNCT
bionys-641	568	47	d.	d.	PROPN
bionys-641	568	48	,	,	PUNCT
bionys-641	568	49	webb	webb	PROPN
bionys-641	568	50	,	,	PUNCT
bionys-641	568	51	a.i	a.i	PROPN
bionys-641	568	52	.	.	PROPN
bionys-641	568	53	,	,	PUNCT
bionys-641	568	54	young	young	PROPN
bionys-641	568	55	,	,	PUNCT
bionys-641	568	56	s.n	s.n	PROPN
bionys-641	568	57	.	.	PROPN
bionys-641	568	58	,	,	PUNCT
bionys-641	568	59	varghese	varghese	PROPN
bionys-641	568	60	,	,	PUNCT
bionys-641	568	61	l.n	l.n	PROPN
bionys-641	568	62	.	.	PROPN
bionys-641	568	63	,	,	PUNCT
bionys-641	568	64	tannahill	tannahill	PROPN
bionys-641	568	65	,	,	PUNCT
bionys-641	568	66	g.m	g.m	PROPN
bionys-641	568	67	.	.	PROPN
bionys-641	568	68	,	,	PUNCT
bionys-641	568	69	hatchell	hatchell	INTJ
bionys-641	568	70	,	,	PUNCT
bionys-641	568	71	e.c	e.c	PROPN
bionys-641	568	72	.	.	PROPN
bionys-641	568	73	,	,	PUNCT
bionys-641	568	74	majewski	majewski	PROPN
bionys-641	568	75	,	,	PUNCT
bionys-641	568	76	i.j	i.j	PROPN
bionys-641	568	77	.	.	PROPN
bionys-641	568	78	,	,	PUNCT
bionys-641	568	79	okamoto	okamoto	PROPN
bionys-641	568	80	,	,	PUNCT
bionys-641	568	81	t.	t.	PROPN
bionys-641	568	82	,	,	PUNCT
bionys-641	568	83	dobson	dobson	PROPN
bionys-641	568	84	,	,	PUNCT
bionys-641	568	85	r.c.j	r.c.j	NOUN
bionys-641	568	86	.	.	PROPN
bionys-641	568	87	,	,	PUNCT
bionys-641	568	88	hilton	hilton	PROPN
bionys-641	568	89	,	,	PUNCT
bionys-641	568	90	d.j	d.j	PROPN
bionys-641	568	91	.	.	PROPN
bionys-641	568	92	,	,	PUNCT
bionys-641	568	93	babon	babon	PROPN
bionys-641	568	94	,	,	PUNCT
bionys-641	568	95	j.j	j.j	PROPN
bionys-641	568	96	.	.	PROPN
bionys-641	568	97	,	,	PUNCT
bionys-641	568	98	nicola	nicola	PROPN
bionys-641	568	99	,	,	PUNCT
bionys-641	568	100	n.a	n.a	PROPN
bionys-641	568	101	.	.	PROPN
bionys-641	568	102	,	,	PUNCT
bionys-641	568	103	strasser	strasser	PROPN
bionys-641	568	104	,	,	PUNCT
bionys-641	568	105	a.	a.	NOUN
bionys-641	568	106	,	,	PUNCT
bionys-641	568	107	silke	silke	NOUN
bionys-641	568	108	,	,	PUNCT
bionys-641	568	109	j.	j.	PROPN
bionys-641	568	110	,	,	PUNCT
bionys-641	568	111	&	&	CCONJ
bionys-641	568	112	alexander	alexander	PROPN
bionys-641	568	113	,	,	PUNCT
bionys-641	568	114	w.s	w.s	PROPN
bionys-641	568	115	.	.	PROPN
bionys-641	568	116	(	(	PUNCT
bionys-641	568	117	2013	2013	NUM
bionys-641	568	118	)	)	PUNCT
bionys-641	568	119	.	.	PUNCT
bionys-641	569	1	the	the	DET
bionys-641	569	2	pseudokinase	pseudokinase	NOUN
bionys-641	569	3	mlkl	mlkl	VERB
bionys-641	569	4	mediates	mediate	NOUN
bionys-641	569	5	necroptosis	necroptosis	NOUN
bionys-641	569	6	via	via	ADP
bionys-641	569	7	a	a	DET
bionys-641	569	8	molecular	molecular	ADJ
bionys-641	569	9	switch	switch	NOUN
bionys-641	569	10	mechanism	mechanism	NOUN
bionys-641	569	11	.	.	PUNCT
bionys-641	570	1	immunity	immunity	NOUN
bionys-641	570	2	,	,	PUNCT
bionys-641	570	3	39(3	39(3	NUM
bionys-641	570	4	)	)	PUNCT
bionys-641	570	5	,	,	PUNCT
bionys-641	570	6	443	443	NUM
bionys-641	570	7	–	–	PUNCT
bionys-641	570	8	453	453	NUM
bionys-641	570	9	.	.	PUNCT
bionys-641	571	1	https://doi.org/10.1016/j.immuni.2013.06.018	https://doi.org/10.1016/j.immuni.2013.06.018	PROPN
bionys-641	571	2	nagasaki	nagasaki	PROPN
bionys-641	571	3	,	,	PUNCT
bionys-641	571	4	j.	j.	PROPN
bionys-641	571	5	,	,	PUNCT
bionys-641	571	6	nishimoto	nishimoto	NOUN
bionys-641	571	7	,	,	PUNCT
bionys-641	571	8	m.	m.	NOUN
bionys-641	571	9	,	,	PUNCT
bionys-641	571	10	koh	koh	PROPN
bionys-641	571	11	,	,	PUNCT
bionys-641	571	12	h.	h.	PROPN
bionys-641	571	13	,	,	PUNCT
bionys-641	571	14	okamura	okamura	PROPN
bionys-641	571	15	,	,	PUNCT
bionys-641	571	16	h.	h.	PROPN
bionys-641	571	17	,	,	PUNCT
bionys-641	571	18	nakamae	nakamae	VERB
bionys-641	571	19	,	,	PUNCT
bionys-641	571	20	m.	m.	NOUN
bionys-641	571	21	,	,	PUNCT
bionys-641	571	22	sakatoku	sakatoku	PROPN
bionys-641	571	23	,	,	PUNCT
bionys-641	571	24	k.	k.	PROPN
bionys-641	571	25	,	,	PUNCT
bionys-641	571	26	ido	ido	PROPN
bionys-641	571	27	,	,	PUNCT
bionys-641	571	28	k.	k.	PROPN
bionys-641	571	29	,	,	PUNCT
bionys-641	571	30	kuno	kuno	PROPN
bionys-641	571	31	,	,	PUNCT
bionys-641	571	32	m.	m.	NOUN
bionys-641	571	33	,	,	PUNCT
bionys-641	571	34	makuuchi	makuuchi	NOUN
bionys-641	571	35	,	,	PUNCT
bionys-641	571	36	y.	y.	PROPN
bionys-641	571	37	,	,	PUNCT
bionys-641	571	38	takakuwa	takakuwa	NOUN
bionys-641	571	39	,	,	PUNCT
bionys-641	571	40	t.	t.	PROPN
bionys-641	571	41	,	,	PUNCT
bionys-641	571	42	nakashima	nakashima	PROPN
bionys-641	571	43	,	,	PUNCT
bionys-641	571	44	y.	y.	PROPN
bionys-641	571	45	,	,	PUNCT
bionys-641	571	46	hino	hino	PROPN
bionys-641	571	47	,	,	PUNCT
bionys-641	571	48	m.	m.	NOUN
bionys-641	571	49	,	,	PUNCT
bionys-641	571	50	&	&	CCONJ
bionys-641	571	51	nakamae	nakamae	PROPN
bionys-641	571	52	,	,	PUNCT
bionys-641	571	53	h.	h.	PROPN
bionys-641	571	54	(	(	PUNCT
bionys-641	571	55	2024	2024	NUM
bionys-641	571	56	)	)	PUNCT
bionys-641	571	57	.	.	PUNCT
bionys-641	572	1	t	t	PROPN
bionys-641	572	2	cells	cell	NOUN
bionys-641	572	3	with	with	ADP
bionys-641	572	4	high	high	ADJ
bionys-641	572	5	bcl-2	bcl-2	NOUN
bionys-641	572	6	expression	expression	NOUN
bionys-641	572	7	induced	induce	VERB
bionys-641	572	8	by	by	ADP
bionys-641	572	9	venetoclax	venetoclax	NOUN
bionys-641	572	10	impact	impact	NOUN
bionys-641	572	11	anti	anti	ADJ
bionys-641	572	12	-	-	ADJ
bionys-641	572	13	leukemic	leukemic	ADJ
bionys-641	572	14	immunity	immunity	NOUN
bionys-641	572	15	“	"	PUNCT
bionys-641	572	16	graft	graft	NOUN
bionys-641	572	17	-	-	PUNCT
bionys-641	572	18	versus	versus	ADP
bionys-641	572	19	-	-	PUNCT
bionys-641	572	20	leukemia	leukemia	NOUN
bionys-641	572	21	effects	effect	NOUN
bionys-641	572	22	”	"	PUNCT
bionys-641	572	23	.	.	PUNCT
bionys-641	573	1	blood	blood	NOUN
bionys-641	573	2	cancer	cancer	NOUN
bionys-641	573	3	journal	journal	NOUN
bionys-641	573	4	,	,	PUNCT
bionys-641	573	5	14(1	14(1	NUM
bionys-641	573	6	)	)	PUNCT
bionys-641	573	7	,	,	PUNCT
bionys-641	573	8	79	79	NUM
bionys-641	573	9	.	.	PUNCT
bionys-641	574	1	https://	https://	PROPN
bionys-641	574	2	doi.org/10.1038/s41408-024-01064-0	doi.org/10.1038/s41408-024-01064-0	PROPN
bionys-641	574	3	nosalova	nosalova	PROPN
bionys-641	574	4	,	,	PUNCT
bionys-641	574	5	n.	n.	PROPN
bionys-641	574	6	,	,	PUNCT
bionys-641	574	7	keselakova	keselakova	PROPN
bionys-641	574	8	,	,	PUNCT
bionys-641	574	9	a.	a.	PROPN
bionys-641	574	10	,	,	PUNCT
bionys-641	574	11	kello	kello	PROPN
bionys-641	574	12	,	,	PUNCT
bionys-641	574	13	m.	m.	NOUN
bionys-641	574	14	,	,	PUNCT
bionys-641	574	15	martinkova	martinkova	PROPN
bionys-641	574	16	,	,	PUNCT
bionys-641	574	17	m.	m.	NOUN
bionys-641	574	18	,	,	PUNCT
bionys-641	574	19	fabianova	fabianova	PROPN
bionys-641	574	20	,	,	PUNCT
bionys-641	574	21	d.	d.	PROPN
bionys-641	574	22	,	,	PUNCT
bionys-641	574	23	&	&	CCONJ
bionys-641	574	24	pilatova	pilatova	PROPN
bionys-641	574	25	,	,	PUNCT
bionys-641	574	26	m.b	m.b	PROPN
bionys-641	574	27	.	.	PROPN
bionys-641	574	28	(	(	PUNCT
bionys-641	574	29	2023	2023	NUM
bionys-641	574	30	)	)	PUNCT
bionys-641	574	31	.	.	PUNCT
bionys-641	575	1	involvement	involvement	NOUN
bionys-641	575	2	of	of	ADP
bionys-641	575	3	both	both	CCONJ
bionys-641	575	4	extrinsic	extrinsic	ADJ
bionys-641	575	5	and	and	CCONJ
bionys-641	575	6	intrinsic	intrinsic	ADJ
bionys-641	575	7	apoptotic	apoptotic	ADJ
bionys-641	575	8	pathways	pathway	NOUN
bionys-641	575	9	in	in	ADP
bionys-641	575	10	tridecylpyrrolidine	tridecylpyrrolidine	NOUN
bionys-641	575	11	-	-	PUNCT
bionys-641	575	12	diol	diol	NOUN
bionys-641	575	13	derivative	derivative	NOUN
bionys-641	575	14	-	-	PUNCT
bionys-641	575	15	induced	induce	VERB
bionys-641	575	16	apoptosis	apoptosis	NOUN
bionys-641	575	17	in	in	ADP
bionys-641	575	18	vitro	vitro	X
bionys-641	575	19	.	.	PUNCT
bionys-641	576	1	international	international	ADJ
bionys-641	576	2	journal	journal	NOUN
bionys-641	576	3	of	of	ADP
bionys-641	576	4	molecular	molecular	ADJ
bionys-641	576	5	sciences	science	NOUN
bionys-641	576	6	,	,	PUNCT
bionys-641	576	7	24(14	24(14	NOUN
bionys-641	576	8	)	)	PUNCT
bionys-641	576	9	,	,	PUNCT
bionys-641	576	10	11696	11696	NUM
bionys-641	576	11	.	.	PUNCT
bionys-641	577	1	https://doi.org/10.3390/ijms241411696	https://doi.org/10.3390/ijms241411696	NOUN
bionys-641	577	2	orzaez	orzaez	NOUN
bionys-641	577	3	,	,	PUNCT
bionys-641	577	4	m.	m.	NOUN
bionys-641	577	5	,	,	PUNCT
bionys-641	577	6	gortat	gortat	PROPN
bionys-641	577	7	,	,	PUNCT
bionys-641	577	8	a.	a.	NOUN
bionys-641	577	9	,	,	PUNCT
bionys-641	577	10	mondragón	mondragón	PROPN
bionys-641	577	11	,	,	PUNCT
bionys-641	577	12	l.	l.	PROPN
bionys-641	577	13	,	,	PUNCT
bionys-641	577	14	&	&	CCONJ
bionys-641	577	15	pérez	pérez	NOUN
bionys-641	577	16	-	-	PUNCT
bionys-641	577	17	payá	payá	NOUN
bionys-641	577	18	,	,	PUNCT
bionys-641	577	19	e.	e.	PROPN
bionys-641	577	20	(	(	PUNCT
bionys-641	577	21	2009	2009	NUM
bionys-641	577	22	)	)	PUNCT
bionys-641	577	23	.	.	PUNCT
bionys-641	578	1	peptides	peptide	NOUN
bionys-641	578	2	and	and	CCONJ
bionys-641	578	3	peptide	peptide	NOUN
bionys-641	578	4	mimics	mimic	NOUN
bionys-641	578	5	as	as	ADP
bionys-641	578	6	modulators	modulator	NOUN
bionys-641	578	7	of	of	ADP
bionys-641	578	8	apoptotic	apoptotic	ADJ
bionys-641	578	9	pathways	pathway	NOUN
bionys-641	578	10	.	.	PUNCT
bionys-641	579	1	chemmedchem	chemmedchem	PROPN
bionys-641	579	2	,	,	PUNCT
bionys-641	579	3	4	4	NUM
bionys-641	579	4	,	,	PUNCT
bionys-641	579	5	146–160	146–160	NUM
bionys-641	579	6	.	.	PUNCT
bionys-641	580	1	https://doi	https://doi	PROPN
bionys-641	580	2	.	.	PUNCT
bionys-641	580	3	org/10.1002	org/10.1002	PROPN
bionys-641	580	4	/	/	SYM
bionys-641	580	5	cmdc.200800246	cmdc.200800246	PROPN
bionys-641	580	6	orzalli	orzalli	PROPN
bionys-641	580	7	,	,	PUNCT
bionys-641	580	8	m.h	m.h	PROPN
bionys-641	580	9	.	.	PROPN
bionys-641	580	10	,	,	PUNCT
bionys-641	580	11	&	&	CCONJ
bionys-641	580	12	kagan	kagan	PROPN
bionys-641	580	13	,	,	PUNCT
bionys-641	580	14	j.c	j.c	PROPN
bionys-641	580	15	.	.	PROPN
bionys-641	580	16	(	(	PUNCT
bionys-641	580	17	2017	2017	NUM
bionys-641	580	18	)	)	PUNCT
bionys-641	580	19	.	.	PUNCT
bionys-641	581	1	apoptosis	apoptosis	NOUN
bionys-641	581	2	and	and	CCONJ
bionys-641	581	3	necroptosis	necroptosis	NOUN
bionys-641	581	4	as	as	ADP
bionys-641	581	5	host	host	NOUN
bionys-641	581	6	defense	defense	NOUN
bionys-641	581	7	strategies	strategy	NOUN
bionys-641	581	8	to	to	PART
bionys-641	581	9	prevent	prevent	VERB
bionys-641	581	10	viral	viral	ADJ
bionys-641	581	11	infection	infection	NOUN
bionys-641	581	12	.	.	PUNCT
bionys-641	582	1	trends	trend	NOUN
bionys-641	582	2	in	in	ADP
bionys-641	582	3	cell	cell	NOUN
bionys-641	582	4	biology	biology	NOUN
bionys-641	582	5	,	,	PUNCT
bionys-641	582	6	27(11	27(11	NUM
bionys-641	582	7	)	)	PUNCT
bionys-641	582	8	,	,	PUNCT
bionys-641	582	9	800	800	NUM
bionys-641	582	10	–	–	PUNCT
bionys-641	582	11	809	809	NUM
bionys-641	582	12	.	.	PUNCT
bionys-641	583	1	https://doi.org/10.1016/j.tcb.2017.05.007	https://doi.org/10.1016/j.tcb.2017.05.007	PROPN
bionys-641	583	2	park	park	PROPN
bionys-641	583	3	,	,	PUNCT
bionys-641	583	4	j.-m	j.-m	PROPN
bionys-641	583	5	.	.	PROPN
bionys-641	583	6	,	,	PUNCT
bionys-641	583	7	jung	jung	PROPN
bionys-641	583	8	,	,	PUNCT
bionys-641	583	9	c.h	c.h	PROPN
bionys-641	583	10	.	.	PROPN
bionys-641	583	11	,	,	PUNCT
bionys-641	583	12	seo	seo	NOUN
bionys-641	583	13	,	,	PUNCT
bionys-641	583	14	m.	m.	NOUN
bionys-641	583	15	,	,	PUNCT
bionys-641	583	16	otto	otto	PROPN
bionys-641	583	17	,	,	PUNCT
bionys-641	583	18	n.m	n.m	PROPN
bionys-641	583	19	.	.	PROPN
bionys-641	583	20	,	,	PUNCT
bionys-641	583	21	grunwald	grunwald	PROPN
bionys-641	583	22	,	,	PUNCT
bionys-641	583	23	d.	d.	PROPN
bionys-641	583	24	,	,	PUNCT
bionys-641	583	25	kim	kim	PROPN
bionys-641	583	26	,	,	PUNCT
bionys-641	583	27	k.h	k.h	PROPN
bionys-641	583	28	.	.	PROPN
bionys-641	583	29	,	,	PUNCT
bionys-641	583	30	moriarity	moriarity	PROPN
bionys-641	583	31	,	,	PUNCT
bionys-641	583	32	b.	b.	PROPN
bionys-641	583	33	,	,	PUNCT
bionys-641	583	34	kim	kim	PROPN
bionys-641	583	35	,	,	PUNCT
bionys-641	583	36	y.m	y.m	PROPN
bionys-641	583	37	.	.	PROPN
bionys-641	583	38	,	,	PUNCT
bionys-641	583	39	starker	starker	PROPN
bionys-641	583	40	,	,	PUNCT
bionys-641	583	41	c.	c.	PROPN
bionys-641	583	42	,	,	PUNCT
bionys-641	583	43	nho	nho	NOUN
bionys-641	583	44	,	,	PUNCT
bionys-641	583	45	r.s	r.s	PROPN
bionys-641	583	46	.	.	PROPN
bionys-641	583	47	,	,	PUNCT
bionys-641	583	48	voytas	voytas	PROPN
bionys-641	583	49	,	,	PUNCT
bionys-641	583	50	d.	d.	PROPN
bionys-641	583	51	,	,	PUNCT
bionys-641	583	52	&	&	CCONJ
bionys-641	583	53	kim	kim	PROPN
bionys-641	583	54	,	,	PUNCT
bionys-641	583	55	d.h	d.h	PROPN
bionys-641	583	56	.	.	PROPN
bionys-641	583	57	(	(	PUNCT
bionys-641	583	58	2016	2016	NUM
bionys-641	583	59	)	)	PUNCT
bionys-641	583	60	.	.	PUNCT
bionys-641	584	1	the	the	DET
bionys-641	584	2	ulk1	ulk1	PROPN
bionys-641	584	3	complex	complex	ADJ
bionys-641	584	4	mediates	mediate	NOUN
bionys-641	584	5	mtorc1	mtorc1	NOUN
bionys-641	584	6	signaling	signal	VERB
bionys-641	584	7	to	to	ADP
bionys-641	584	8	the	the	DET
bionys-641	584	9	autophagy	autophagy	ADJ
bionys-641	584	10	initiation	initiation	NOUN
bionys-641	584	11	machinery	machinery	NOUN
bionys-641	584	12	via	via	ADP
bionys-641	584	13	binding	bind	VERB
bionys-641	584	14	and	and	CCONJ
bionys-641	584	15	phosphorylating	phosphorylate	VERB
bionys-641	584	16	atg14	atg14	NOUN
bionys-641	584	17	.	.	PUNCT
bionys-641	585	1	autophagy	autophagy	ADJ
bionys-641	585	2	,	,	PUNCT
bionys-641	585	3	12(3	12(3	NUM
bionys-641	585	4	)	)	PUNCT
bionys-641	585	5	,	,	PUNCT
bionys-641	585	6	547–564	547–564	NUM
bionys-641	585	7	.	.	PUNCT
bionys-641	586	1	https://doi.org/10.1080/15548627	https://doi.org/10.1080/15548627	X
bionys-641	586	2	.	.	PUNCT
bionys-641	587	1	2016.1140293	2016.1140293	NUM
bionys-641	587	2	park	park	NOUN
bionys-641	587	3	,	,	PUNCT
bionys-641	587	4	m.h	m.h	PROPN
bionys-641	587	5	.	.	PROPN
bionys-641	587	6	,	,	PUNCT
bionys-641	587	7	song	song	NOUN
bionys-641	587	8	,	,	PUNCT
bionys-641	587	9	m.j	m.j	PROPN
bionys-641	587	10	.	.	PROPN
bionys-641	587	11	,	,	PUNCT
bionys-641	587	12	cho	cho	PROPN
bionys-641	587	13	,	,	PUNCT
bionys-641	587	14	m.-c	m.-c	PROPN
bionys-641	587	15	.	.	PUNCT
bionys-641	587	16	,	,	PUNCT
bionys-641	587	17	moon	moon	PROPN
bionys-641	587	18	,	,	PUNCT
bionys-641	587	19	d.c	d.c	PROPN
bionys-641	587	20	.	.	PROPN
bionys-641	587	21	,	,	PUNCT
bionys-641	587	22	yoon	yoon	PROPN
bionys-641	587	23	,	,	PUNCT
bionys-641	587	24	d.y	d.y	PROPN
bionys-641	587	25	.	.	PROPN
bionys-641	587	26	,	,	PUNCT
bionys-641	587	27	han	han	PROPN
bionys-641	587	28	,	,	PUNCT
bionys-641	587	29	s.b	s.b	PROPN
bionys-641	587	30	.	.	PROPN
bionys-641	587	31	,	,	PUNCT
bionys-641	587	32	&	&	CCONJ
bionys-641	587	33	hong	hong	PROPN
bionys-641	587	34	,	,	PUNCT
bionys-641	587	35	j.t	j.t	PROPN
bionys-641	587	36	.	.	PROPN
bionys-641	587	37	(	(	PUNCT
bionys-641	587	38	2012	2012	NUM
bionys-641	587	39	)	)	PUNCT
bionys-641	587	40	.	.	PUNCT
bionys-641	588	1	interleukin-32	interleukin-32	NOUN
bionys-641	588	2	enhances	enhance	VERB
bionys-641	588	3	cytotoxic	cytotoxic	ADJ
bionys-641	588	4	effect	effect	NOUN
bionys-641	588	5	of	of	ADP
bionys-641	588	6	natural	natural	ADJ
bionys-641	588	7	killer	killer	NOUN
bionys-641	588	8	cells	cell	NOUN
bionys-641	588	9	to	to	ADP
bionys-641	588	10	cancer	cancer	NOUN
bionys-641	588	11	cells	cell	NOUN
bionys-641	588	12	via	via	ADP
bionys-641	588	13	activation	activation	NOUN
bionys-641	588	14	of	of	ADP
bionys-641	588	15	death	death	NOUN
bionys-641	588	16	receptor	receptor	NOUN
bionys-641	588	17	3	3	X
bionys-641	588	18	.	.	PUNCT
bionys-641	588	19	immunology	immunology	NOUN
bionys-641	588	20	,	,	PUNCT
bionys-641	588	21	135(1	135(1	NUM
bionys-641	588	22	)	)	PUNCT
bionys-641	588	23	,	,	PUNCT
bionys-641	588	24	63–72	63–72	NUM
bionys-641	588	25	.	.	PUNCT
bionys-641	589	1	https://doi	https://doi	NOUN
bionys-641	589	2	.	.	PUNCT
bionys-641	589	3	org/10.1111	org/10.1111	PROPN
bionys-641	589	4	/	/	SYM
bionys-641	589	5	j.1365	j.1365	NOUN
bionys-641	589	6	-	-	PUNCT
bionys-641	589	7	2567.2011.03513.x	2567.2011.03513.x	NUM
bionys-641	589	8	park	park	NOUN
bionys-641	589	9	,	,	PUNCT
bionys-641	589	10	w.	w.	PROPN
bionys-641	589	11	,	,	PUNCT
bionys-641	589	12	wei	wei	PROPN
bionys-641	589	13	,	,	PUNCT
bionys-641	589	14	s.	s.	PROPN
bionys-641	589	15	,	,	PUNCT
bionys-641	589	16	kim	kim	PROPN
bionys-641	589	17	,	,	PUNCT
bionys-641	589	18	b.-s	b.-s	PROPN
bionys-641	589	19	.	.	PUNCT
bionys-641	589	20	,	,	PUNCT
bionys-641	589	21	kim	kim	PROPN
bionys-641	589	22	,	,	PUNCT
bionys-641	589	23	b.	b.	PROPN
bionys-641	589	24	,	,	PUNCT
bionys-641	589	25	bae	bae	PROPN
bionys-641	589	26	,	,	PUNCT
bionys-641	589	27	s.-j	s.-j	PROPN
bionys-641	589	28	.	.	PROPN
bionys-641	589	29	,	,	PUNCT
bionys-641	589	30	chae	chae	PROPN
bionys-641	589	31	,	,	PUNCT
bionys-641	589	32	y.c	y.c	PROPN
bionys-641	589	33	.	.	PROPN
bionys-641	589	34	,	,	PUNCT
bionys-641	589	35	ryu	ryu	PROPN
bionys-641	589	36	,	,	PUNCT
bionys-641	589	37	d.	d.	PROPN
bionys-641	589	38	,	,	PUNCT
bionys-641	589	39	&	&	CCONJ
bionys-641	589	40	ha	ha	INTJ
bionys-641	589	41	,	,	PUNCT
bionys-641	589	42	k.-t	k.-t	PROPN
bionys-641	589	43	.	.	PUNCT
bionys-641	590	1	(	(	PUNCT
bionys-641	590	2	2023	2023	NUM
bionys-641	590	3	)	)	PUNCT
bionys-641	590	4	.	.	PUNCT
bionys-641	591	1	diversity	diversity	NOUN
bionys-641	591	2	and	and	CCONJ
bionys-641	591	3	complexity	complexity	NOUN
bionys-641	591	4	of	of	ADP
bionys-641	591	5	cell	cell	NOUN
bionys-641	591	6	death	death	NOUN
bionys-641	591	7	:	:	PUNCT
bionys-641	591	8	a	a	DET
bionys-641	591	9	historical	historical	ADJ
bionys-641	591	10	review	review	NOUN
bionys-641	591	11	.	.	PUNCT
bionys-641	592	1	experimental	experimental	ADJ
bionys-641	592	2	&	&	CCONJ
bionys-641	592	3	molecular	molecular	ADJ
bionys-641	592	4	medicine	medicine	NOUN
bionys-641	592	5	,	,	PUNCT
bionys-641	592	6	55(8	55(8	NUM
bionys-641	592	7	)	)	PUNCT
bionys-641	592	8	,	,	PUNCT
bionys-641	592	9	1573	1573	NUM
bionys-641	592	10	–	–	PUNCT
bionys-641	592	11	1594	1594	NUM
bionys-641	592	12	.	.	PUNCT
bionys-641	593	1	https://doi.org/10.1038/s12276-023-01078-x	https://doi.org/10.1038/s12276-023-01078-x	PROPN
bionys-641	593	2	pierce	pierce	PROPN
bionys-641	593	3	,	,	PUNCT
bionys-641	593	4	a.	a.	PROPN
bionys-641	593	5	,	,	PUNCT
bionys-641	593	6	whetton	whetton	PROPN
bionys-641	593	7	,	,	PUNCT
bionys-641	593	8	a.d	a.d	PROPN
bionys-641	593	9	.	.	PROPN
bionys-641	593	10	,	,	PUNCT
bionys-641	593	11	meyer	meyer	PROPN
bionys-641	593	12	,	,	PUNCT
bionys-641	593	13	s.	s.	PROPN
bionys-641	593	14	,	,	PUNCT
bionys-641	593	15	ravandikashani	ravandikashani	PROPN
bionys-641	593	16	,	,	PUNCT
bionys-641	593	17	f.	f.	PROPN
bionys-641	593	18	,	,	PUNCT
bionys-641	593	19	borthakur	borthakur	PROPN
bionys-641	593	20	,	,	PUNCT
bionys-641	593	21	g.	g.	PROPN
bionys-641	593	22	,	,	PUNCT
bionys-641	593	23	coombes	coombes	PROPN
bionys-641	593	24	,	,	PUNCT
bionys-641	593	25	k.r	k.r	PROPN
bionys-641	593	26	.	.	PROPN
bionys-641	593	27	,	,	PUNCT
bionys-641	593	28	zhang	zhang	PROPN
bionys-641	593	29	,	,	PUNCT
bionys-641	593	30	n.	n.	PROPN
bionys-641	593	31	,	,	PUNCT
bionys-641	593	32	&	&	CCONJ
bionys-641	593	33	kornblau	kornblau	PROPN
bionys-641	593	34	,	,	PUNCT
bionys-641	593	35	s.	s.	PROPN
bionys-641	593	36	(	(	PUNCT
bionys-641	593	37	2013	2013	NUM
bionys-641	593	38	)	)	PUNCT
bionys-641	593	39	.	.	PUNCT
bionys-641	594	1	transglutaminase	transglutaminase	NOUN
bionys-641	594	2	2	2	NUM
bionys-641	594	3	expression	expression	NOUN
bionys-641	594	4	in	in	ADP
bionys-641	594	5	acute	acute	ADJ
bionys-641	594	6	myeloid	myeloid	ADJ
bionys-641	594	7	leukemia	leukemia	NOUN
bionys-641	594	8	:	:	PUNCT
bionys-641	594	9	association	association	NOUN
bionys-641	594	10	with	with	ADP
bionys-641	594	11	adhesion	adhesion	NOUN
bionys-641	594	12	molecule	molecule	NOUN
bionys-641	594	13	expression	expression	NOUN
bionys-641	594	14	and	and	CCONJ
bionys-641	594	15	leukemic	leukemic	ADJ
bionys-641	594	16	blast	blast	NOUN
bionys-641	594	17	motility	motility	NOUN
bionys-641	594	18	.	.	PUNCT
bionys-641	595	1	proteomics	proteomic	NOUN
bionys-641	595	2	,	,	PUNCT
bionys-641	595	3	13(14	13(14	NUM
bionys-641	595	4	)	)	PUNCT
bionys-641	595	5	,	,	PUNCT
bionys-641	595	6	2216–2224	2216–2224	NUM
bionys-641	595	7	.	.	PUNCT
bionys-641	596	1	https://doi.org/10.1002/pmic.201200471	https://doi.org/10.1002/pmic.201200471	PROPN
bionys-641	596	2	portt	portt	PROPN
bionys-641	596	3	,	,	PUNCT
bionys-641	596	4	l.	l.	PROPN
bionys-641	596	5	,	,	PUNCT
bionys-641	596	6	norman	norman	PROPN
bionys-641	596	7	,	,	PUNCT
bionys-641	596	8	g.	g.	PROPN
bionys-641	596	9	,	,	PUNCT
bionys-641	596	10	clapp	clapp	PROPN
bionys-641	596	11	,	,	PUNCT
bionys-641	596	12	c.	c.	PROPN
bionys-641	596	13	,	,	PUNCT
bionys-641	596	14	greenwood	greenwood	PROPN
bionys-641	596	15	,	,	PUNCT
bionys-641	596	16	m.	m.	NOUN
bionys-641	596	17	,	,	PUNCT
bionys-641	596	18	&	&	CCONJ
bionys-641	596	19	greenwood	greenwood	PROPN
bionys-641	596	20	,	,	PUNCT
bionys-641	596	21	m.t	m.t	PROPN
bionys-641	596	22	.	.	PROPN
bionys-641	596	23	(	(	PUNCT
bionys-641	596	24	2011	2011	NUM
bionys-641	596	25	)	)	PUNCT
bionys-641	596	26	.	.	PUNCT
bionys-641	597	1	anti	anti	ADJ
bionys-641	597	2	-	-	ADJ
bionys-641	597	3	apoptosis	apoptosis	ADJ
bionys-641	597	4	and	and	CCONJ
bionys-641	597	5	cell	cell	NOUN
bionys-641	597	6	survival	survival	NOUN
bionys-641	597	7	:	:	PUNCT
bionys-641	597	8	a	a	DET
bionys-641	597	9	review	review	NOUN
bionys-641	597	10	.	.	PUNCT
bionys-641	598	1	biochimica	biochimica	PROPN
bionys-641	598	2	et	et	PROPN
bionys-641	598	3	biophysica	biophysica	PROPN
bionys-641	598	4	acta	acta	PROPN
bionys-641	598	5	(	(	PUNCT
bionys-641	598	6	bba	bba	NOUN
bionys-641	598	7	)	)	PUNCT
bionys-641	598	8	molecular	molecular	ADJ
bionys-641	598	9	cell	cell	NOUN
bionys-641	598	10	research	research	NOUN
bionys-641	598	11	,	,	PUNCT
bionys-641	598	12	1813(1	1813(1	NUM
bionys-641	598	13	)	)	PUNCT
bionys-641	598	14	,	,	PUNCT
bionys-641	598	15	238	238	NUM
bionys-641	598	16	–	–	SYM
bionys-641	598	17	259	259	NUM
bionys-641	598	18	.	.	X
bionys-641	599	1	https://doi.org/10.1016/j.bbamcr.2010.10.010	https://doi.org/10.1016/j.bbamcr.2010.10.010	PROPN
bionys-641	599	2	schulze	schulze	NOUN
bionys-641	599	3	-	-	PUNCT
bionys-641	599	4	osthoff	osthoff	NOUN
bionys-641	599	5	,	,	PUNCT
bionys-641	599	6	k.	k.	PROPN
bionys-641	599	7	,	,	PUNCT
bionys-641	599	8	ferrari	ferrari	PROPN
bionys-641	599	9	,	,	PUNCT
bionys-641	599	10	d.	d.	PROPN
bionys-641	599	11	,	,	PUNCT
bionys-641	599	12	los	los	PROPN
bionys-641	599	13	,	,	PUNCT
bionys-641	599	14	m.	m.	NOUN
bionys-641	599	15	,	,	PUNCT
bionys-641	599	16	wesselborg	wesselborg	NOUN
bionys-641	599	17	,	,	PUNCT
bionys-641	599	18	s.	s.	PROPN
bionys-641	599	19	,	,	PUNCT
bionys-641	599	20	&	&	CCONJ
bionys-641	599	21	peter	peter	PROPN
bionys-641	599	22	,	,	PUNCT
bionys-641	599	23	m.e	m.e	PROPN
bionys-641	599	24	.	.	PROPN
bionys-641	599	25	(	(	PUNCT
bionys-641	599	26	1998	1998	NUM
bionys-641	599	27	)	)	PUNCT
bionys-641	599	28	.	.	PUNCT
bionys-641	600	1	apoptosis	apoptosis	NOUN
bionys-641	600	2	signaling	signal	VERB
bionys-641	600	3	by	by	ADP
bionys-641	600	4	death	death	NOUN
bionys-641	600	5	receptors	receptor	NOUN
bionys-641	600	6	.	.	PUNCT
bionys-641	601	1	european	european	ADJ
bionys-641	601	2	journal	journal	PROPN
bionys-641	601	3	of	of	ADP
bionys-641	601	4	biochemistry	biochemistry	NOUN
bionys-641	601	5	,	,	PUNCT
bionys-641	601	6	254(3	254(3	NUM
bionys-641	601	7	)	)	PUNCT
bionys-641	601	8	,	,	PUNCT
bionys-641	601	9	439–459	439–459	NUM
bionys-641	601	10	.	.	PUNCT
bionys-641	602	1	https://doi	https://doi	PROPN
bionys-641	602	2	.	.	PUNCT
bionys-641	602	3	org/10.1046	org/10.1046	NOUN
bionys-641	602	4	/	/	SYM
bionys-641	602	5	j.1432	j.1432	NOUN
bionys-641	602	6	-	-	PUNCT
bionys-641	602	7	1327.1998.2540439.x	1327.1998.2540439.x	NUM
bionys-641	602	8	schweichel	schweichel	PROPN
bionys-641	602	9	,	,	PUNCT
bionys-641	602	10	j.u	j.u	PROPN
bionys-641	602	11	.	.	PROPN
bionys-641	602	12	&	&	CCONJ
bionys-641	602	13	merker	merker	PROPN
bionys-641	602	14	,	,	PUNCT
bionys-641	602	15	h.j	h.j	PROPN
bionys-641	602	16	.	.	PROPN
bionys-641	602	17	(	(	PUNCT
bionys-641	602	18	1973	1973	NUM
bionys-641	602	19	)	)	PUNCT
bionys-641	602	20	.	.	PUNCT
bionys-641	603	1	the	the	DET
bionys-641	603	2	morphology	morphology	NOUN
bionys-641	603	3	of	of	ADP
bionys-641	603	4	various	various	ADJ
bionys-641	603	5	types	type	NOUN
bionys-641	603	6	of	of	ADP
bionys-641	603	7	cell	cell	NOUN
bionys-641	603	8	death	death	NOUN
bionys-641	603	9	in	in	ADP
bionys-641	603	10	prenatal	prenatal	ADJ
bionys-641	603	11	tissues	tissue	NOUN
bionys-641	603	12	.	.	PUNCT
bionys-641	604	1	teratology	teratology	NOUN
bionys-641	604	2	,	,	PUNCT
bionys-641	604	3	7(3	7(3	NUM
bionys-641	604	4	)	)	PUNCT
bionys-641	604	5	,	,	PUNCT
bionys-641	604	6	253–266	253–266	NUM
bionys-641	604	7	.	.	PUNCT
bionys-641	605	1	https://doi	https://doi	PROPN
bionys-641	605	2	.	.	PUNCT
bionys-641	605	3	org/10.1002	org/10.1002	PROPN
bionys-641	605	4	/	/	SYM
bionys-641	605	5	tera.1420070306	tera.1420070306	PROPN
bionys-641	605	6	settembre	settembre	PROPN
bionys-641	605	7	,	,	PUNCT
bionys-641	605	8	c.	c.	PROPN
bionys-641	605	9	,	,	PUNCT
bionys-641	605	10	fraldi	fraldi	NOUN
bionys-641	605	11	,	,	PUNCT
bionys-641	605	12	a.	a.	PROPN
bionys-641	605	13	,	,	PUNCT
bionys-641	605	14	medina	medina	PROPN
bionys-641	605	15	,	,	PUNCT
bionys-641	605	16	d.l	d.l	PROPN
bionys-641	605	17	.	.	PROPN
bionys-641	605	18	,	,	PUNCT
bionys-641	605	19	&	&	CCONJ
bionys-641	605	20	ballabio	ballabio	PROPN
bionys-641	605	21	,	,	PUNCT
bionys-641	605	22	a.	a.	NOUN
bionys-641	605	23	(	(	PUNCT
bionys-641	605	24	2013	2013	NUM
bionys-641	605	25	)	)	PUNCT
bionys-641	605	26	.	.	PUNCT
bionys-641	606	1	signals	signal	NOUN
bionys-641	606	2	from	from	ADP
bionys-641	606	3	the	the	DET
bionys-641	606	4	lysosome	lysosome	NOUN
bionys-641	606	5	:	:	PUNCT
bionys-641	606	6	a	a	DET
bionys-641	606	7	control	control	NOUN
bionys-641	606	8	centre	centre	NOUN
bionys-641	606	9	for	for	ADP
bionys-641	606	10	cellular	cellular	ADJ
bionys-641	606	11	clearance	clearance	NOUN
bionys-641	606	12	and	and	CCONJ
bionys-641	606	13	energy	energy	NOUN
bionys-641	606	14	metabolism	metabolism	NOUN
bionys-641	606	15	.	.	PUNCT
bionys-641	607	1	nature	nature	NOUN
bionys-641	607	2	reviews	review	NOUN
bionys-641	607	3	.	.	PUNCT
bionys-641	608	1	molecular	molecular	ADJ
bionys-641	608	2	cell	cell	NOUN
bionys-641	608	3	biology	biology	NOUN
bionys-641	608	4	,	,	PUNCT
bionys-641	608	5	14(5	14(5	NUM
bionys-641	608	6	)	)	PUNCT
bionys-641	608	7	,	,	PUNCT
bionys-641	608	8	283–296	283–296	NUM
bionys-641	608	9	.	.	PUNCT
bionys-641	609	1	https://doi.org/10.1038/	https://doi.org/10.1038/	PROPN
bionys-641	609	2	nrm3565	nrm3565	ADV
bionys-641	609	3	sheffield	sheffield	PROPN
bionys-641	609	4	,	,	PUNCT
bionys-641	609	5	l.g	l.g	PROPN
bionys-641	609	6	.	.	PROPN
bionys-641	609	7	,	,	PUNCT
bionys-641	609	8	miskiewicz	miskiewicz	PROPN
bionys-641	609	9	,	,	PUNCT
bionys-641	609	10	h.b	h.b	PROPN
bionys-641	609	11	.	.	PROPN
bionys-641	609	12	,	,	PUNCT
bionys-641	609	13	tannenbaum	tannenbaum	PROPN
bionys-641	609	14	,	,	PUNCT
bionys-641	609	15	l.b	l.b	PROPN
bionys-641	609	16	.	.	PROPN
bionys-641	609	17	,	,	PUNCT
bionys-641	609	18	&	&	CCONJ
bionys-641	609	19	mirra	mirra	PROPN
bionys-641	609	20	,	,	PUNCT
bionys-641	609	21	s.s	s.s	PROPN
bionys-641	609	22	.	.	PROPN
bionys-641	609	23	(	(	PUNCT
bionys-641	609	24	2006	2006	NUM
bionys-641	609	25	)	)	PUNCT
bionys-641	609	26	.	.	PUNCT
bionys-641	610	1	nuclear	nuclear	ADJ
bionys-641	610	2	pore	pore	ADJ
bionys-641	610	3	complex	complex	ADJ
bionys-641	610	4	proteins	protein	NOUN
bionys-641	610	5	in	in	ADP
bionys-641	610	6	alzheimer	alzheimer	PROPN
bionys-641	610	7	disease	disease	PROPN
bionys-641	610	8	.	.	PUNCT
bionys-641	611	1	journal	journal	PROPN
bionys-641	611	2	of	of	ADP
bionys-641	611	3	neuropathology	neuropathology	NOUN
bionys-641	611	4	&	&	CCONJ
bionys-641	611	5	experimental	experimental	ADJ
bionys-641	611	6	neurology	neurology	NOUN
bionys-641	611	7	,	,	PUNCT
bionys-641	611	8	65(1	65(1	NOUN
bionys-641	611	9	)	)	PUNCT
bionys-641	611	10	,	,	PUNCT
bionys-641	611	11	45–54	45–54	NUM
bionys-641	611	12	.	.	PUNCT
bionys-641	612	1	https://doi.org/10.1097/01	https://doi.org/10.1097/01	ADJ
bionys-641	612	2	.	.	PUNCT
bionys-641	613	1	jnen.0000195939.40410.08	jnen.0000195939.40410.08	PROPN
bionys-641	613	2	solari	solari	PROPN
bionys-641	613	3	,	,	PUNCT
bionys-641	613	4	j.i.g	j.i.g	PROPN
bionys-641	613	5	.	.	PROPN
bionys-641	613	6	,	,	PUNCT
bionys-641	613	7	filippi	filippi	PROPN
bionys-641	613	8	-	-	PUNCT
bionys-641	613	9	chiela	chiela	PROPN
bionys-641	613	10	,	,	PUNCT
bionys-641	613	11	e.	e.	PROPN
bionys-641	613	12	,	,	PUNCT
bionys-641	613	13	pilar	pilar	PROPN
bionys-641	613	14	,	,	PUNCT
bionys-641	613	15	e.s	e.s	PROPN
bionys-641	613	16	.	.	PROPN
bionys-641	613	17	,	,	PUNCT
bionys-641	613	18	nunes	nunes	PROPN
bionys-641	613	19	,	,	PUNCT
bionys-641	613	20	v.	v.	PROPN
bionys-641	613	21	,	,	PUNCT
bionys-641	613	22	gonzalez	gonzalez	PROPN
bionys-641	613	23	,	,	PUNCT
bionys-641	613	24	e.a	e.a	PROPN
bionys-641	613	25	.	.	PROPN
bionys-641	613	26	,	,	PUNCT
bionys-641	613	27	figueiró	figueiró	PROPN
bionys-641	613	28	,	,	PUNCT
bionys-641	613	29	f.	f.	PROPN
bionys-641	613	30	,	,	PUNCT
bionys-641	613	31	andrade	andrade	PROPN
bionys-641	613	32	,	,	PUNCT
bionys-641	613	33	c.f	c.f	PROPN
bionys-641	613	34	.	.	PROPN
bionys-641	613	35	,	,	PUNCT
bionys-641	613	36	&	&	CCONJ
bionys-641	613	37	klamt	klamt	PROPN
bionys-641	613	38	,	,	PUNCT
bionys-641	613	39	f.	f.	PROPN
bionys-641	613	40	(	(	PUNCT
bionys-641	613	41	2020	2020	NUM
bionys-641	613	42	)	)	PUNCT
bionys-641	613	43	.	.	PUNCT
bionys-641	614	1	damage	damage	NOUN
bionys-641	614	2	-	-	PUNCT
bionys-641	614	3	associated	associate	VERB
bionys-641	614	4	molecular	molecular	ADJ
bionys-641	614	5	patterns	pattern	NOUN
bionys-641	614	6	(	(	PUNCT
bionys-641	614	7	damps	damps	PROPN
bionys-641	614	8	)	)	PUNCT
bionys-641	614	9	related	relate	VERB
bionys-641	614	10	to	to	ADP
bionys-641	614	11	immunogenic	immunogenic	ADJ
bionys-641	614	12	cell	cell	NOUN
bionys-641	614	13	death	death	NOUN
bionys-641	614	14	are	be	AUX
bionys-641	614	15	differentially	differentially	ADV
bionys-641	614	16	triggered	trigger	VERB
bionys-641	614	17	by	by	ADP
bionys-641	614	18	clinically	clinically	ADV
bionys-641	614	19	relevant	relevant	ADJ
bionys-641	614	20	chemotherapeutics	chemotherapeutic	NOUN
bionys-641	614	21	in	in	ADP
bionys-641	614	22	lung	lung	NOUN
bionys-641	614	23	adenocarcinoma	adenocarcinoma	NOUN
bionys-641	614	24	cells	cell	NOUN
bionys-641	614	25	.	.	PUNCT
bionys-641	615	1	bmc	bmc	ADJ
bionys-641	615	2	cancer	cancer	NOUN
bionys-641	615	3	,	,	PUNCT
bionys-641	615	4	20(1	20(1	NUM
bionys-641	615	5	)	)	PUNCT
bionys-641	615	6	,	,	PUNCT
bionys-641	615	7	474	474	NUM
bionys-641	615	8	.	.	PUNCT
bionys-641	616	1	https://doi.org/10.1186/	https://doi.org/10.1186/	PROPN
bionys-641	616	2	s12885	s12885	PROPN
bionys-641	616	3	-	-	PUNCT
bionys-641	616	4	020	020	NUM
bionys-641	616	5	-	-	PUNCT
bionys-641	616	6	06964	06964	NUM
bionys-641	616	7	-	-	SYM
bionys-641	616	8	5	5	NUM
bionys-641	616	9	song	song	NOUN
bionys-641	616	10	,	,	PUNCT
bionys-641	616	11	x.	x.	PROPN
bionys-641	616	12	,	,	PUNCT
bionys-641	616	13	zhu	zhu	PROPN
bionys-641	616	14	,	,	PUNCT
bionys-641	616	15	s.	s.	PROPN
bionys-641	616	16	,	,	PUNCT
bionys-641	616	17	xie	xie	PROPN
bionys-641	616	18	,	,	PUNCT
bionys-641	616	19	y.	y.	PROPN
bionys-641	616	20	,	,	PUNCT
bionys-641	616	21	liu	liu	PROPN
bionys-641	616	22	,	,	PUNCT
bionys-641	616	23	j.	j.	PROPN
bionys-641	616	24	,	,	PUNCT
bionys-641	616	25	sun	sun	PROPN
bionys-641	616	26	,	,	PUNCT
bionys-641	616	27	l.	l.	PROPN
bionys-641	616	28	,	,	PUNCT
bionys-641	616	29	zeng	zeng	PROPN
bionys-641	616	30	,	,	PUNCT
bionys-641	616	31	d.	d.	PROPN
bionys-641	616	32	,	,	PUNCT
bionys-641	616	33	wang	wang	PROPN
bionys-641	616	34	,	,	PUNCT
bionys-641	616	35	p.	p.	PROPN
bionys-641	616	36	,	,	PUNCT
bionys-641	616	37	ma	ma	PROPN
bionys-641	616	38	,	,	PUNCT
bionys-641	616	39	x.	x.	PROPN
bionys-641	616	40	,	,	PUNCT
bionys-641	616	41	kroemer	kroemer	PROPN
bionys-641	616	42	,	,	PUNCT
bionys-641	616	43	g.	g.	PROPN
bionys-641	616	44	,	,	PUNCT
bionys-641	616	45	bartlett	bartlett	PROPN
bionys-641	616	46	,	,	PUNCT
bionys-641	616	47	d.l	d.l	PROPN
bionys-641	616	48	.	.	PROPN
bionys-641	616	49	,	,	PUNCT
bionys-641	616	50	billiar	billiar	PROPN
bionys-641	616	51	,	,	PUNCT
bionys-641	616	52	t.r	t.r	PROPN
bionys-641	616	53	.	.	PROPN
bionys-641	616	54	,	,	PUNCT
bionys-641	616	55	lotze	lotze	PROPN
bionys-641	616	56	,	,	PUNCT
bionys-641	616	57	m.t	m.t	PROPN
bionys-641	616	58	.	.	PROPN
bionys-641	616	59	,	,	PUNCT
bionys-641	616	60	zeh	zeh	PROPN
bionys-641	616	61	,	,	PUNCT
bionys-641	616	62	h.j	h.j	PROPN
bionys-641	616	63	.	.	PROPN
bionys-641	616	64	,	,	PUNCT
bionys-641	616	65	kang	kang	PROPN
bionys-641	616	66	,	,	PUNCT
bionys-641	616	67	r.	r.	PROPN
bionys-641	616	68	,	,	PUNCT
bionys-641	616	69	&	&	CCONJ
bionys-641	616	70	tang	tang	PROPN
bionys-641	616	71	,	,	PUNCT
bionys-641	616	72	d.	d.	PROPN
bionys-641	616	73	(	(	PUNCT
bionys-641	616	74	2018	2018	NUM
bionys-641	616	75	)	)	PUNCT
bionys-641	616	76	.	.	PUNCT
bionys-641	617	1	jtc801	jtc801	PROPN
bionys-641	617	2	induces	induce	VERB
bionys-641	617	3	ph	ph	ADJ
bionys-641	617	4	-	-	ADJ
bionys-641	617	5	dependent	dependent	ADJ
bionys-641	617	6	death	death	NOUN
bionys-641	617	7	specifically	specifically	ADV
bionys-641	617	8	in	in	ADP
bionys-641	617	9	cancer	cancer	NOUN
bionys-641	617	10	cells	cell	NOUN
bionys-641	617	11	and	and	CCONJ
bionys-641	617	12	slows	slow	VERB
bionys-641	617	13	growth	growth	NOUN
bionys-641	617	14	of	of	ADP
bionys-641	617	15	tumors	tumor	NOUN
bionys-641	617	16	in	in	ADP
bionys-641	617	17	mice	mouse	NOUN
bionys-641	617	18	.	.	PUNCT
bionys-641	618	1	gastroenterology	gastroenterology	NOUN
bionys-641	618	2	,	,	PUNCT
bionys-641	618	3	154(5	154(5	NUM
bionys-641	618	4	)	)	PUNCT
bionys-641	618	5	,	,	PUNCT
bionys-641	618	6	1480	1480	NUM
bionys-641	618	7	–	–	PUNCT
bionys-641	618	8	1493	1493	NUM
bionys-641	618	9	.	.	PUNCT
bionys-641	619	1	https://doi.org/10.1053/j.gastro.2017.12.004	https://doi.org/10.1053/j.gastro.2017.12.004	PROPN
bionys-641	619	2	spiesser	spiesser	PROPN
bionys-641	619	3	,	,	PUNCT
bionys-641	619	4	t.w	t.w	PROPN
bionys-641	619	5	.	.	PROPN
bionys-641	619	6	,	,	PUNCT
bionys-641	619	7	müller	müller	PROPN
bionys-641	619	8	,	,	PUNCT
bionys-641	619	9	c.	c.	PROPN
bionys-641	619	10	,	,	PUNCT
bionys-641	619	11	schreiber	schreiber	PROPN
bionys-641	619	12	,	,	PUNCT
bionys-641	619	13	g.	g.	PROPN
bionys-641	619	14	,	,	PUNCT
bionys-641	619	15	krantz	krantz	PROPN
bionys-641	619	16	,	,	PUNCT
bionys-641	619	17	m.	m.	NOUN
bionys-641	619	18	,	,	PUNCT
bionys-641	619	19	&	&	CCONJ
bionys-641	619	20	klipp	klipp	PROPN
bionys-641	619	21	,	,	PUNCT
bionys-641	619	22	e.	e.	PROPN
bionys-641	619	23	(	(	PUNCT
bionys-641	619	24	2012	2012	NUM
bionys-641	619	25	)	)	PUNCT
bionys-641	619	26	.	.	PUNCT
bionys-641	620	1	size	size	NOUN
bionys-641	620	2	homeostasis	homeostasis	NOUN
bionys-641	620	3	can	can	AUX
bionys-641	620	4	be	be	AUX
bionys-641	620	5	intrinsic	intrinsic	ADJ
bionys-641	620	6	to	to	ADP
bionys-641	620	7	growing	grow	VERB
bionys-641	620	8	cell	cell	NOUN
bionys-641	620	9	populations	population	NOUN
bionys-641	620	10	and	and	CCONJ
bionys-641	620	11	explained	explain	VERB
bionys-641	620	12	without	without	ADP
bionys-641	620	13	size	size	NOUN
bionys-641	620	14	sensing	sense	VERB
bionys-641	620	15	or	or	CCONJ
bionys-641	620	16	signalling	signal	VERB
bionys-641	620	17	.	.	PUNCT
bionys-641	621	1	the	the	DET
bionys-641	621	2	febs	febs	NOUN
bionys-641	621	3	journal	journal	NOUN
bionys-641	621	4	,	,	PUNCT
bionys-641	621	5	279(22	279(22	NUM
bionys-641	621	6	)	)	PUNCT
bionys-641	621	7	,	,	PUNCT
bionys-641	621	8	4213–4230	4213–4230	NUM
bionys-641	621	9	.	.	PUNCT
bionys-641	622	1	https://doi	https://doi	PROPN
bionys-641	622	2	.	.	PUNCT
bionys-641	622	3	org/10.1111	org/10.1111	PROPN
bionys-641	622	4	/	/	SYM
bionys-641	622	5	febs.12014	febs.12014	PROPN
bionys-641	622	6	stilgenbauer	stilgenbauer	NOUN
bionys-641	622	7	,	,	PUNCT
bionys-641	622	8	s.	s.	PROPN
bionys-641	622	9	,	,	PUNCT
bionys-641	622	10	eichhorst	eichhorst	PROPN
bionys-641	622	11	,	,	PUNCT
bionys-641	622	12	b.	b.	PROPN
bionys-641	622	13	,	,	PUNCT
bionys-641	622	14	schetelig	schetelig	PROPN
bionys-641	622	15	,	,	PUNCT
bionys-641	622	16	j.	j.	PROPN
bionys-641	622	17	,	,	PUNCT
bionys-641	622	18	coutre	coutre	NOUN
bionys-641	622	19	,	,	PUNCT
bionys-641	622	20	s.	s.	PROPN
bionys-641	622	21	,	,	PUNCT
bionys-641	622	22	seymour	seymour	PROPN
bionys-641	622	23	,	,	PUNCT
bionys-641	622	24	j.	j.	PROPN
bionys-641	622	25	,	,	PUNCT
bionys-641	622	26	munir	munir	PROPN
bionys-641	622	27	,	,	PUNCT
bionys-641	622	28	t.	t.	PROPN
bionys-641	622	29	,	,	PUNCT
bionys-641	622	30	puvvada	puvvada	PROPN
bionys-641	622	31	,	,	PUNCT
bionys-641	622	32	s.	s.	PROPN
bionys-641	622	33	,	,	PUNCT
bionys-641	622	34	wendtner	wendtner	NOUN
bionys-641	622	35	,	,	PUNCT
bionys-641	622	36	c.-m	c.-m	NOUN
bionys-641	622	37	.	.	PUNCT
bionys-641	622	38	,	,	PUNCT
bionys-641	622	39	roberts	roberts	PROPN
bionys-641	622	40	,	,	PUNCT
bionys-641	622	41	a.	a.	PROPN
bionys-641	622	42	,	,	PUNCT
bionys-641	622	43	jurczak	jurczak	PROPN
bionys-641	622	44	,	,	PUNCT
bionys-641	622	45	w.	w.	PROPN
bionys-641	622	46	,	,	PUNCT
bionys-641	622	47	mulligan	mulligan	PROPN
bionys-641	622	48	,	,	PUNCT
bionys-641	622	49	s.	s.	PROPN
bionys-641	622	50	,	,	PUNCT
bionys-641	622	51	böttcher	böttcher	PROPN
bionys-641	622	52	,	,	PUNCT
bionys-641	622	53	s.	s.	PROPN
bionys-641	622	54	,	,	PUNCT
bionys-641	622	55	mobasher	mobasher	NOUN
bionys-641	622	56	,	,	PUNCT
bionys-641	622	57	m.	m.	NOUN
bionys-641	622	58	,	,	PUNCT
bionys-641	622	59	zhu	zhu	PROPN
bionys-641	622	60	,	,	PUNCT
bionys-641	622	61	m.	m.	NOUN
bionys-641	622	62	,	,	PUNCT
bionys-641	622	63	desai	desai	PROPN
bionys-641	622	64	,	,	PUNCT
bionys-641	622	65	m.	m.	NOUN
bionys-641	622	66	,	,	PUNCT
bionys-641	622	67	chyla	chyla	PROPN
bionys-641	622	68	,	,	PUNCT
bionys-641	622	69	b.	b.	PROPN
bionys-641	622	70	,	,	PUNCT
bionys-641	622	71	verdugo	verdugo	PROPN
bionys-641	622	72	,	,	PUNCT
bionys-641	622	73	m.	m.	NOUN
bionys-641	622	74	,	,	PUNCT
bionys-641	622	75	enschede	enschede	PROPN
bionys-641	622	76	,	,	PUNCT
bionys-641	622	77	s.	s.	PROPN
bionys-641	622	78	,	,	PUNCT
bionys-641	622	79	&	&	CCONJ
bionys-641	622	80	cerri	cerri	PROPN
bionys-641	622	81	,	,	PUNCT
bionys-641	622	82	e.	e.	PROPN
bionys-641	622	83	(	(	PUNCT
bionys-641	622	84	2016	2016	NUM
bionys-641	622	85	)	)	PUNCT
bionys-641	622	86	.	.	PUNCT
bionys-641	623	1	venetoclax	venetoclax	PROPN
bionys-641	623	2	in	in	ADP
bionys-641	623	3	relapsed	relapse	VERB
bionys-641	623	4	or	or	CCONJ
bionys-641	623	5	refractory	refractory	NOUN
bionys-641	623	6	chronic	chronic	ADJ
bionys-641	623	7	lymphocytic	lymphocytic	ADJ
bionys-641	623	8	leukaemia	leukaemia	NOUN
bionys-641	623	9	with	with	ADP
bionys-641	623	10	17p	17p	NOUN
bionys-641	623	11	deletion	deletion	NOUN
bionys-641	623	12	:	:	PUNCT
bionys-641	623	13	a	a	DET
bionys-641	623	14	multicentre	multicentre	NOUN
bionys-641	623	15	,	,	PUNCT
bionys-641	623	16	open	open	ADJ
bionys-641	623	17	-	-	PUNCT
bionys-641	623	18	label	label	NOUN
bionys-641	623	19	,	,	PUNCT
bionys-641	623	20	phase	phase	NOUN
bionys-641	623	21	2	2	NUM
bionys-641	623	22	study	study	NOUN
bionys-641	623	23	.	.	PUNCT
bionys-641	624	1	the	the	DET
bionys-641	624	2	lancet	lancet	PROPN
bionys-641	624	3	oncology	oncology	NOUN
bionys-641	624	4	,	,	PUNCT
bionys-641	624	5	17	17	NUM
bionys-641	624	6	,	,	PUNCT
bionys-641	624	7	768–778	768–778	NUM
bionys-641	624	8	.	.	PUNCT
bionys-641	625	1	https://doi	https://doi	X
bionys-641	625	2	.	.	PUNCT
bionys-641	625	3	org/10.1016	org/10.1016	PROPN
bionys-641	625	4	/	/	SYM
bionys-641	625	5	s1470	s1470	PROPN
bionys-641	625	6	-	-	PUNCT
bionys-641	625	7	2045(16)30019	2045(16)30019	NUM
bionys-641	625	8	-	-	SYM
bionys-641	625	9	5	5	NUM
bionys-641	625	10	stockwell	stockwell	PROPN
bionys-641	625	11	,	,	PUNCT
bionys-641	625	12	b.r	b.r	PROPN
bionys-641	625	13	.	.	PROPN
bionys-641	625	14	,	,	PUNCT
bionys-641	625	15	jiang	jiang	PROPN
bionys-641	625	16	,	,	PUNCT
bionys-641	625	17	x.	x.	PROPN
bionys-641	625	18	,	,	PUNCT
bionys-641	625	19	&	&	CCONJ
bionys-641	625	20	gu	gu	PROPN
bionys-641	625	21	,	,	PUNCT
bionys-641	625	22	w.	w.	PROPN
bionys-641	625	23	(	(	PUNCT
bionys-641	625	24	2020	2020	NUM
bionys-641	625	25	)	)	PUNCT
bionys-641	625	26	.	.	PUNCT
bionys-641	626	1	emerging	emerge	VERB
bionys-641	626	2	mechanisms	mechanism	NOUN
bionys-641	626	3	and	and	CCONJ
bionys-641	626	4	disease	disease	NOUN
bionys-641	626	5	relevance	relevance	NOUN
bionys-641	626	6	of	of	ADP
bionys-641	626	7	ferroptosis	ferroptosis	NOUN
bionys-641	626	8	.	.	PUNCT
bionys-641	627	1	trends	trend	NOUN
bionys-641	627	2	in	in	ADP
bionys-641	627	3	cell	cell	NOUN
bionys-641	627	4	biology	biology	NOUN
bionys-641	627	5	,	,	PUNCT
bionys-641	627	6	30(6	30(6	NUM
bionys-641	627	7	)	)	PUNCT
bionys-641	627	8	,	,	PUNCT
bionys-641	627	9	478–490	478–490	NUM
bionys-641	627	10	.	.	PUNCT
bionys-641	627	11	https://doi.org/10.1016/j.tcb.2020.02.009	https://doi.org/10.1016/j.tcb.2020.02.009	PROPN
bionys-641	627	12	sun	sun	PROPN
bionys-641	627	13	,	,	PUNCT
bionys-641	627	14	s.	s.	PROPN
bionys-641	627	15	&	&	CCONJ
bionys-641	627	16	mei	mei	PROPN
bionys-641	627	17	,	,	PUNCT
bionys-641	627	18	x.	x.	NOUN
bionys-641	627	19	(	(	PUNCT
bionys-641	627	20	2024	2024	NUM
bionys-641	627	21	)	)	PUNCT
bionys-641	627	22	.	.	PUNCT
bionys-641	628	1	effect	effect	NOUN
bionys-641	628	2	of	of	ADP
bionys-641	628	3	casc15	casc15	NOUN
bionys-641	628	4	on	on	ADP
bionys-641	628	5	apoptosis	apoptosis	NOUN
bionys-641	628	6	and	and	CCONJ
bionys-641	628	7	oxidative	oxidative	ADJ
bionys-641	628	8	stress	stress	NOUN
bionys-641	628	9	of	of	ADP
bionys-641	628	10	cardiomyocytes	cardiomyocyte	NOUN
bionys-641	628	11	after	after	ADP
bionys-641	628	12	hypoxia	hypoxia	NOUN
bionys-641	628	13	/	/	SYM
bionys-641	628	14	reperfusion	reperfusion	NOUN
bionys-641	628	15	injury	injury	NOUN
bionys-641	628	16	.	.	PUNCT
bionys-641	629	1	revista	revista	PROPN
bionys-641	629	2	portuguesa	portuguesa	PROPN
bionys-641	629	3	de	de	PROPN
bionys-641	629	4	cardiologia	cardiologia	PROPN
bionys-641	629	5	,	,	PUNCT
bionys-641	629	6	43(2	43(2	NUM
bionys-641	629	7	)	)	PUNCT
bionys-641	629	8	,	,	PUNCT
bionys-641	629	9	77–84	77–84	PROPN
bionys-641	629	10	.	.	PUNCT
bionys-641	630	1	https://	https://	PROPN
bionys-641	630	2	doi.org/10.1016/j.repc.2023.04.017	doi.org/10.1016/j.repc.2023.04.017	SYM
bionys-641	630	3	suzanne	suzanne	PROPN
bionys-641	630	4	,	,	PUNCT
bionys-641	630	5	m.	m.	NOUN
bionys-641	630	6	&	&	CCONJ
bionys-641	630	7	steller	steller	PROPN
bionys-641	630	8	,	,	PUNCT
bionys-641	630	9	h.	h.	PROPN
bionys-641	630	10	(	(	PUNCT
bionys-641	630	11	2013	2013	NUM
bionys-641	630	12	)	)	PUNCT
bionys-641	630	13	.	.	PUNCT
bionys-641	631	1	shaping	shape	VERB
bionys-641	631	2	organisms	organism	NOUN
bionys-641	631	3	with	with	ADP
bionys-641	631	4	apoptosis	apoptosis	NOUN
bionys-641	631	5	.	.	PUNCT
bionys-641	632	1	cell	cell	NOUN
bionys-641	632	2	death	death	NOUN
bionys-641	632	3	and	and	CCONJ
bionys-641	632	4	differentiation	differentiation	NOUN
bionys-641	632	5	,	,	PUNCT
bionys-641	632	6	20(5	20(5	NOUN
bionys-641	632	7	)	)	PUNCT
bionys-641	632	8	,	,	PUNCT
bionys-641	632	9	669–675	669–675	NUM
bionys-641	632	10	.	.	PUNCT
bionys-641	633	1	https://doi	https://doi	NOUN
bionys-641	633	2	.	.	PUNCT
bionys-641	633	3	org/10.1038	org/10.1038	PROPN
bionys-641	633	4	/	/	SYM
bionys-641	633	5	cdd.2013.11	cdd.2013.11	PROPN
bionys-641	633	6	taddei	taddei	NOUN
bionys-641	633	7	,	,	PUNCT
bionys-641	633	8	m.l	m.l	PROPN
bionys-641	633	9	.	.	PROPN
bionys-641	633	10	,	,	PUNCT
bionys-641	633	11	giannoni	giannoni	PROPN
bionys-641	633	12	,	,	PUNCT
bionys-641	633	13	e.	e.	PROPN
bionys-641	633	14	,	,	PUNCT
bionys-641	633	15	fiaschi	fiaschi	ADJ
bionys-641	633	16	,	,	PUNCT
bionys-641	633	17	t.	t.	PROPN
bionys-641	633	18	,	,	PUNCT
bionys-641	633	19	&	&	CCONJ
bionys-641	633	20	chiarugi	chiarugi	PROPN
bionys-641	633	21	,	,	PUNCT
bionys-641	633	22	p.	p.	NOUN
bionys-641	633	23	(	(	PUNCT
bionys-641	633	24	2012	2012	NUM
bionys-641	633	25	)	)	PUNCT
bionys-641	633	26	.	.	PUNCT
bionys-641	634	1	anoikis	anoiki	NOUN
bionys-641	634	2	:	:	PUNCT
bionys-641	634	3	an	an	DET
bionys-641	634	4	emerging	emerge	VERB
bionys-641	634	5	hallmark	hallmark	NOUN
bionys-641	634	6	in	in	ADP
bionys-641	634	7	health	health	NOUN
bionys-641	634	8	and	and	CCONJ
bionys-641	634	9	diseases	disease	NOUN
bionys-641	634	10	.	.	PUNCT
bionys-641	635	1	the	the	DET
bionys-641	635	2	journal	journal	NOUN
bionys-641	635	3	of	of	ADP
bionys-641	635	4	pathology	pathology	NOUN
bionys-641	635	5	,	,	PUNCT
bionys-641	635	6	226(2	226(2	NUM
bionys-641	635	7	)	)	PUNCT
bionys-641	635	8	,	,	PUNCT
bionys-641	635	9	380–393	380–393	NUM
bionys-641	635	10	.	.	PUNCT
bionys-641	635	11	https://doi.org/10.1002/path.3000	https://doi.org/10.1002/path.3000	PROPN
bionys-641	635	12	tang	tang	PROPN
bionys-641	635	13	,	,	PUNCT
bionys-641	635	14	d.	d.	PROPN
bionys-641	635	15	,	,	PUNCT
bionys-641	635	16	kang	kang	PROPN
bionys-641	635	17	,	,	PUNCT
bionys-641	635	18	r.	r.	PROPN
bionys-641	635	19	,	,	PUNCT
bionys-641	635	20	berghe	berghe	NOUN
bionys-641	635	21	,	,	PUNCT
bionys-641	635	22	t.v	t.v	PROPN
bionys-641	635	23	.	.	PROPN
bionys-641	635	24	,	,	PUNCT
bionys-641	635	25	vandenabeele	vandenabeele	PROPN
bionys-641	635	26	,	,	PUNCT
bionys-641	635	27	p.	p.	PROPN
bionys-641	635	28	,	,	PUNCT
bionys-641	635	29	&	&	CCONJ
bionys-641	635	30	kroemer	kroemer	PROPN
bionys-641	635	31	,	,	PUNCT
bionys-641	635	32	g.	g.	PROPN
bionys-641	635	33	(	(	PUNCT
bionys-641	635	34	2019	2019	NUM
bionys-641	635	35	)	)	PUNCT
bionys-641	635	36	.	.	PUNCT
bionys-641	636	1	the	the	DET
bionys-641	636	2	molecular	molecular	ADJ
bionys-641	636	3	machinery	machinery	NOUN
bionys-641	636	4	of	of	ADP
bionys-641	636	5	regulated	regulated	ADJ
bionys-641	636	6	cell	cell	NOUN
bionys-641	636	7	death	death	NOUN
bionys-641	636	8	.	.	PUNCT
bionys-641	637	1	cell	cell	NOUN
bionys-641	637	2	research	research	NOUN
bionys-641	637	3	,	,	PUNCT
bionys-641	637	4	29(5	29(5	NUM
bionys-641	637	5	)	)	PUNCT
bionys-641	637	6	,	,	PUNCT
bionys-641	637	7	347	347	NUM
bionys-641	637	8	–	–	PUNCT
bionys-641	637	9	364	364	NUM
bionys-641	637	10	.	.	PUNCT
bionys-641	637	11	https://doi.org/10.1038/s41422-019-0164-5	https://doi.org/10.1038/s41422-019-0164-5	NOUN
bionys-641	637	12	thiruppathi	thiruppathi	PROPN
bionys-641	637	13	,	,	PUNCT
bionys-641	637	14	j.	j.	PROPN
bionys-641	637	15	,	,	PUNCT
bionys-641	637	16	vijayan	vijayan	PROPN
bionys-641	637	17	,	,	PUNCT
bionys-641	637	18	v.	v.	PROPN
bionys-641	637	19	,	,	PUNCT
bionys-641	637	20	park	park	NOUN
bionys-641	637	21	,	,	PUNCT
bionys-641	637	22	i.-k	i.-k	PROPN
bionys-641	637	23	.	.	PUNCT
bionys-641	637	24	,	,	PUNCT
bionys-641	637	25	lee	lee	PROPN
bionys-641	637	26	,	,	PUNCT
bionys-641	637	27	s.e	s.e	PROPN
bionys-641	637	28	.	.	PROPN
bionys-641	637	29	,	,	PUNCT
bionys-641	637	30	&	&	CCONJ
bionys-641	637	31	rhee	rhee	PROPN
bionys-641	637	32	,	,	PUNCT
bionys-641	637	33	j.h	j.h	PROPN
bionys-641	637	34	.	.	PROPN
bionys-641	637	35	(	(	PUNCT
bionys-641	637	36	2024	2024	NUM
bionys-641	637	37	)	)	PUNCT
bionys-641	637	38	.	.	PUNCT
bionys-641	638	1	enhancing	enhance	VERB
bionys-641	638	2	cancer	cancer	NOUN
bionys-641	638	3	immunotherapy	immunotherapy	NOUN
bionys-641	638	4	with	with	ADP
bionys-641	638	5	photodynamic	photodynamic	ADJ
bionys-641	638	6	therapy	therapy	NOUN
bionys-641	638	7	and	and	CCONJ
bionys-641	638	8	nanoparticle	nanoparticle	NOUN
bionys-641	638	9	:	:	PUNCT
bionys-641	638	10	making	make	VERB
bionys-641	638	11	tumor	tumor	NOUN
bionys-641	638	12	microenvironment	microenvironment	NOUN
bionys-641	638	13	hotter	hotter	ADV
bionys-641	638	14	to	to	PART
bionys-641	638	15	make	make	VERB
bionys-641	638	16	immunotherapeutic	immunotherapeutic	ADJ
bionys-641	638	17	work	work	NOUN
bionys-641	638	18	better	well	ADV
bionys-641	638	19	.	.	PUNCT
bionys-641	639	1	frontiers	frontier	NOUN
bionys-641	639	2	in	in	ADP
bionys-641	639	3	immunology	immunology	NOUN
bionys-641	639	4	,	,	PUNCT
bionys-641	639	5	15	15	NUM
bionys-641	639	6	,	,	PUNCT
bionys-641	639	7	1375767	1375767	NUM
bionys-641	639	8	.	.	PUNCT
bionys-641	640	1	https://doi	https://doi	PROPN
bionys-641	640	2	.	.	PUNCT
bionys-641	640	3	org/10.3389	org/10.3389	PROPN
bionys-641	640	4	/	/	SYM
bionys-641	640	5	fimmu.2024.1375767	fimmu.2024.1375767	NOUN
bionys-641	640	6	todde	todde	VERB
bionys-641	640	7	,	,	PUNCT
bionys-641	640	8	v.	v.	ADV
bionys-641	640	9	,	,	PUNCT
bionys-641	640	10	veenhuis	veenhuis	ADV
bionys-641	640	11	,	,	PUNCT
bionys-641	640	12	m.	m.	NOUN
bionys-641	640	13	,	,	PUNCT
bionys-641	640	14	&	&	CCONJ
bionys-641	640	15	van	van	PROPN
bionys-641	640	16	der	der	PROPN
bionys-641	640	17	klei	klei	PROPN
bionys-641	640	18	,	,	PUNCT
bionys-641	640	19	i.j	i.j	PROPN
bionys-641	640	20	.	.	PROPN
bionys-641	640	21	(	(	PUNCT
bionys-641	640	22	2009	2009	NUM
bionys-641	640	23	)	)	PUNCT
bionys-641	640	24	.	.	PUNCT
bionys-641	641	1	autophagy	autophagy	ADV
bionys-641	641	2	:	:	PUNCT
bionys-641	641	3	principles	principle	NOUN
bionys-641	641	4	and	and	CCONJ
bionys-641	641	5	significance	significance	NOUN
bionys-641	641	6	in	in	ADP
bionys-641	641	7	health	health	NOUN
bionys-641	641	8	and	and	CCONJ
bionys-641	641	9	disease	disease	NOUN
bionys-641	641	10	.	.	PUNCT
bionys-641	642	1	biochimica	biochimica	PROPN
bionys-641	642	2	et	et	PROPN
bionys-641	642	3	biophysica	biophysica	PROPN
bionys-641	642	4	acta	acta	PROPN
bionys-641	642	5	(	(	PUNCT
bionys-641	642	6	bba	bba	NOUN
bionys-641	642	7	)	)	PUNCT
bionys-641	642	8	molecular	molecular	ADJ
bionys-641	642	9	basis	basis	NOUN
bionys-641	642	10	of	of	ADP
bionys-641	642	11	disease	disease	NOUN
bionys-641	642	12	,	,	PUNCT
bionys-641	642	13	1792(1	1792(1	NUM
bionys-641	642	14	)	)	PUNCT
bionys-641	642	15	,	,	PUNCT
bionys-641	642	16	3–13	3–13	NUM
bionys-641	642	17	.	.	PUNCT
bionys-641	643	1	https://doi.org/10.1016/j.bbadis.2008.10.016	https://doi.org/10.1016/j.bbadis.2008.10.016	PROPN
bionys-641	643	2	ucciero	ucciero	PROPN
bionys-641	643	3	,	,	PUNCT
bionys-641	643	4	a.	a.	PROPN
bionys-641	643	5	,	,	PUNCT
bionys-641	643	6	pagnoni	pagnoni	PROPN
bionys-641	643	7	,	,	PUNCT
bionys-641	643	8	f.	f.	PROPN
bionys-641	643	9	,	,	PUNCT
bionys-641	643	10	scotti	scotti	PROPN
bionys-641	643	11	,	,	PUNCT
bionys-641	643	12	l.	l.	PROPN
bionys-641	643	13	,	,	PUNCT
bionys-641	643	14	pisterna	pisterna	PROPN
bionys-641	643	15	,	,	PUNCT
bionys-641	643	16	a.	a.	NOUN
bionys-641	643	17	,	,	PUNCT
bionys-641	643	18	barone	barone	NOUN
bionys-641	643	19	-	-	PUNCT
bionys-641	643	20	adesi	adesi	NOUN
bionys-641	643	21	,	,	PUNCT
bionys-641	643	22	f.	f.	PROPN
bionys-641	643	23	,	,	PUNCT
bionys-641	643	24	gaidano	gaidano	PROPN
bionys-641	643	25	,	,	PUNCT
bionys-641	643	26	g.	g.	PROPN
bionys-641	643	27	,	,	PUNCT
bionys-641	643	28	patriarca	patriarca	NOUN
bionys-641	643	29	,	,	PUNCT
bionys-641	643	30	a.	a.	NOUN
bionys-641	643	31	,	,	PUNCT
bionys-641	643	32	&	&	CCONJ
bionys-641	643	33	lunghi	lunghi	PROPN
bionys-641	643	34	,	,	PUNCT
bionys-641	643	35	m.	m.	NOUN
bionys-641	643	36	(	(	PUNCT
bionys-641	643	37	2023	2023	NUM
bionys-641	643	38	)	)	PUNCT
bionys-641	643	39	.	.	PUNCT
bionys-641	644	1	venetoclax	venetoclax	NOUN
bionys-641	644	2	with	with	ADP
bionys-641	644	3	hypomethylating	hypomethylate	VERB
bionys-641	644	4	agents	agent	NOUN
bionys-641	644	5	in	in	ADP
bionys-641	644	6	newly	newly	ADV
bionys-641	644	7	diagnosed	diagnose	VERB
bionys-641	644	8	acute	acute	ADJ
bionys-641	644	9	myeloid	myeloid	NOUN
bionys-641	644	10	leukemia	leukemia	NOUN
bionys-641	644	11	:	:	PUNCT
bionys-641	644	12	a	a	DET
bionys-641	644	13	systematic	systematic	ADJ
bionys-641	644	14	review	review	NOUN
bionys-641	644	15	and	and	CCONJ
bionys-641	644	16	meta	meta	ADJ
bionys-641	644	17	-	-	PUNCT
bionys-641	644	18	analysis	analysis	NOUN
bionys-641	644	19	of	of	ADP
bionys-641	644	20	survival	survival	NOUN
bionys-641	644	21	data	datum	NOUN
bionys-641	644	22	from	from	ADP
bionys-641	644	23	realworld	realworld	PROPN
bionys-641	644	24	studies	study	NOUN
bionys-641	644	25	.	.	PUNCT
bionys-641	645	1	cancers	cancer	NOUN
bionys-641	645	2	,	,	PUNCT
bionys-641	645	3	15(18	15(18	NUM
bionys-641	645	4	)	)	PUNCT
bionys-641	645	5	,	,	PUNCT
bionys-641	645	6	4618	4618	NUM
bionys-641	645	7	.	.	PUNCT
bionys-641	646	1	https://doi	https://doi	X
bionys-641	646	2	.	.	PUNCT
bionys-641	646	3	org/10.3390	org/10.3390	PROPN
bionys-641	646	4	/	/	SYM
bionys-641	646	5	cancers15184618	cancers15184618	PROPN
bionys-641	646	6	van	van	NOUN
bionys-641	646	7	der	der	PROPN
bionys-641	646	8	meeren	meeren	PROPN
bionys-641	646	9	,	,	PUNCT
bionys-641	646	10	l.	l.	PROPN
bionys-641	646	11	,	,	PUNCT
bionys-641	646	12	verduijn	verduijn	PROPN
bionys-641	646	13	,	,	PUNCT
bionys-641	646	14	j.	j.	PROPN
bionys-641	646	15	,	,	PUNCT
bionys-641	646	16	krysko	krysko	PROPN
bionys-641	646	17	,	,	PUNCT
bionys-641	646	18	d.v	d.v	PROPN
bionys-641	646	19	,	,	PUNCT
bionys-641	646	20	&	&	CCONJ
bionys-641	646	21	skirtach	skirtach	PROPN
bionys-641	646	22	,	,	PUNCT
bionys-641	646	23	a.g	a.g	PROPN
bionys-641	646	24	.	.	PROPN
bionys-641	646	25	(	(	PUNCT
bionys-641	646	26	2023	2023	NUM
bionys-641	646	27	)	)	PUNCT
bionys-641	646	28	.	.	PUNCT
bionys-641	647	1	high	high	ADJ
bionys-641	647	2	-	-	PUNCT
bionys-641	647	3	throughput	throughput	NOUN
bionys-641	647	4	mechano	mechano	PROPN
bionys-641	647	5	-	-	PUNCT
bionys-641	647	6	cytometry	cytometry	PROPN
bionys-641	647	7	as	as	ADP
bionys-641	647	8	a	a	DET
bionys-641	647	9	method	method	NOUN
bionys-641	647	10	to	to	PART
bionys-641	647	11	detect	detect	VERB
bionys-641	647	12	apoptosis	apoptosis	NOUN
bionys-641	647	13	,	,	PUNCT
bionys-641	647	14	necroptosis	necroptosis	NOUN
bionys-641	647	15	,	,	PUNCT
bionys-641	647	16	and	and	CCONJ
bionys-641	647	17	ferroptosis	ferroptosis	NOUN
bionys-641	647	18	.	.	PUNCT
bionys-641	648	1	cell	cell	NOUN
bionys-641	648	2	proliferation	proliferation	NOUN
bionys-641	648	3	,	,	PUNCT
bionys-641	648	4	56(6	56(6	NUM
bionys-641	648	5	)	)	PUNCT
bionys-641	648	6	,	,	PUNCT
bionys-641	648	7	e13445	e13445	NOUN
bionys-641	648	8	.	.	PUNCT
bionys-641	649	1	https://doi.org/10.1111/cpr.13445	https://doi.org/10.1111/cpr.13445	PROPN
bionys-641	649	2	vandenabeele	vandenabeele	PROPN
bionys-641	649	3	,	,	PUNCT
bionys-641	649	4	p.	p.	NOUN
bionys-641	649	5	,	,	PUNCT
bionys-641	649	6	grootjans	grootjans	PROPN
bionys-641	649	7	,	,	PUNCT
bionys-641	649	8	s.	s.	PROPN
bionys-641	649	9	,	,	PUNCT
bionys-641	649	10	callewaert	callewaert	PROPN
bionys-641	649	11	,	,	PUNCT
bionys-641	649	12	n.	n.	NOUN
bionys-641	649	13	,	,	PUNCT
bionys-641	649	14	&	&	CCONJ
bionys-641	649	15	takahashi	takahashi	PROPN
bionys-641	649	16	,	,	PUNCT
bionys-641	649	17	n.	n.	PROPN
bionys-641	649	18	(	(	PUNCT
bionys-641	649	19	2013	2013	NUM
bionys-641	649	20	)	)	PUNCT
bionys-641	649	21	.	.	PUNCT
bionys-641	650	1	necrostatin-1	necrostatin-1	NUM
bionys-641	650	2	blocks	block	VERB
bionys-641	650	3	both	both	DET
bionys-641	650	4	ripk1	ripk1	NOUN
bionys-641	650	5	and	and	CCONJ
bionys-641	650	6	ido	ido	NOUN
bionys-641	650	7	:	:	PUNCT
bionys-641	650	8	consequences	consequence	NOUN
bionys-641	650	9	for	for	ADP
bionys-641	650	10	the	the	DET
bionys-641	650	11	study	study	NOUN
bionys-641	650	12	of	of	ADP
bionys-641	650	13	cell	cell	NOUN
bionys-641	650	14	death	death	NOUN
bionys-641	650	15	in	in	ADP
bionys-641	650	16	experimental	experimental	ADJ
bionys-641	650	17	disease	disease	NOUN
bionys-641	650	18	models	model	NOUN
bionys-641	650	19	.	.	PUNCT
bionys-641	651	1	cell	cell	NOUN
bionys-641	651	2	death	death	NOUN
bionys-641	651	3	&	&	CCONJ
bionys-641	651	4	differentiation	differentiation	NOUN
bionys-641	651	5	,	,	PUNCT
bionys-641	651	6	20(2	20(2	NUM
bionys-641	651	7	)	)	PUNCT
bionys-641	651	8	,	,	PUNCT
bionys-641	651	9	185–187	185–187	NUM
bionys-641	651	10	.	.	PUNCT
bionys-641	652	1	https://	https://	PROPN
bionys-641	652	2	doi.org/10.1038/cdd.2012.151	doi.org/10.1038/cdd.2012.151	PUNCT
bionys-641	652	3	biologica	biologica	NOUN
bionys-641	652	4	nyssana	nyssana	PROPN
bionys-641	652	5	●	●	PUNCT
bionys-641	652	6	16	16	NUM
bionys-641	652	7	(	(	PUNCT
bionys-641	652	8	2	2	NUM
bionys-641	652	9	)	)	PUNCT
bionys-641	652	10	december	december	PROPN
bionys-641	652	11	2025	2025	NUM
bionys-641	652	12	:	:	PUNCT
bionys-641	652	13	liana	liana	NOUN
bionys-641	652	14	et	et	PROPN
bionys-641	652	15	al	al	PROPN
bionys-641	652	16	.	.	PUNCT
bionys-641	653	1	●	●	PUNCT
bionys-641	653	2	cell	cell	NOUN
bionys-641	653	3	deaths	death	NOUN
bionys-641	653	4	and	and	CCONJ
bionys-641	653	5	their	their	PRON
bionys-641	653	6	associated	associate	VERB
bionys-641	653	7	mechanisms	mechanism	NOUN
bionys-641	653	8	biologica	biologica	PROPN
bionys-641	653	9	nyssana	nyssana	PROPN
bionys-641	653	10	●	●	PUNCT
bionys-641	653	11	16	16	NUM
bionys-641	653	12	(	(	PUNCT
bionys-641	653	13	2	2	NUM
bionys-641	653	14	)	)	PUNCT
bionys-641	653	15	december	december	PROPN
bionys-641	653	16	2025	2025	NUM
bionys-641	653	17	:	:	PUNCT
bionys-641	653	18	liana	liana	NOUN
bionys-641	653	19	et	et	PROPN
bionys-641	653	20	al	al	PROPN
bionys-641	653	21	.	.	PUNCT
bionys-641	654	1	●	●	PUNCT
bionys-641	654	2	cell	cell	NOUN
bionys-641	654	3	deaths	death	NOUN
bionys-641	654	4	and	and	CCONJ
bionys-641	654	5	their	their	PRON
bionys-641	654	6	associated	associate	VERB
bionys-641	654	7	mechanisms	mechanism	NOUN
bionys-641	654	8	vekariya	vekariya	NOUN
bionys-641	654	9	,	,	PUNCT
bionys-641	654	10	u.	u.	PROPN
bionys-641	654	11	,	,	PUNCT
bionys-641	654	12	minakhin	minakhin	PROPN
bionys-641	654	13	,	,	PUNCT
bionys-641	654	14	l.	l.	PROPN
bionys-641	654	15	,	,	PUNCT
bionys-641	654	16	chandramouly	chandramouly	PROPN
bionys-641	654	17	,	,	PUNCT
bionys-641	654	18	g.	g.	PROPN
bionys-641	654	19	,	,	PUNCT
bionys-641	654	20	tyagi	tyagi	PROPN
bionys-641	654	21	,	,	PUNCT
bionys-641	654	22	m.	m.	NOUN
bionys-641	654	23	,	,	PUNCT
bionys-641	654	24	kent	kent	PROPN
bionys-641	654	25	,	,	PUNCT
bionys-641	654	26	t.	t.	PROPN
bionys-641	654	27	,	,	PUNCT
bionys-641	654	28	sullivan	sullivan	PROPN
bionys-641	654	29	-	-	PUNCT
bionys-641	654	30	reed	reed	PROPN
bionys-641	654	31	,	,	PUNCT
bionys-641	654	32	k.	k.	PROPN
bionys-641	654	33	,	,	PUNCT
bionys-641	654	34	atkins	atkins	PROPN
bionys-641	654	35	,	,	PUNCT
bionys-641	654	36	j.	j.	PROPN
bionys-641	654	37	,	,	PUNCT
bionys-641	654	38	ralph	ralph	PROPN
bionys-641	654	39	,	,	PUNCT
bionys-641	654	40	d.	d.	PROPN
bionys-641	654	41	,	,	PUNCT
bionys-641	654	42	nieborowska	nieborowska	NOUN
bionys-641	654	43	-	-	PUNCT
bionys-641	654	44	skorska	skorska	PROPN
bionys-641	654	45	,	,	PUNCT
bionys-641	654	46	m.	m.	NOUN
bionys-641	654	47	,	,	PUNCT
bionys-641	654	48	kukuyan	kukuyan	ADJ
bionys-641	654	49	,	,	PUNCT
bionys-641	654	50	a.-m	a.-m	PROPN
bionys-641	654	51	.	.	PUNCT
bionys-641	654	52	,	,	PUNCT
bionys-641	654	53	tang	tang	PROPN
bionys-641	654	54	,	,	PUNCT
bionys-641	654	55	h.-y	h.-y	NOUN
bionys-641	654	56	.	.	PUNCT
bionys-641	654	57	,	,	PUNCT
bionys-641	654	58	pomerantz	pomerantz	NOUN
bionys-641	654	59	,	,	PUNCT
bionys-641	654	60	r.t	r.t	PROPN
bionys-641	654	61	.	.	PROPN
bionys-641	654	62	,	,	PUNCT
bionys-641	654	63	&	&	CCONJ
bionys-641	654	64	skorski	skorski	ADJ
bionys-641	654	65	,	,	PUNCT
bionys-641	654	66	t.	t.	PROPN
bionys-641	654	67	(	(	PUNCT
bionys-641	654	68	2024	2024	NUM
bionys-641	654	69	)	)	PUNCT
bionys-641	654	70	.	.	PUNCT
bionys-641	655	1	parg	parg	PROPN
bionys-641	655	2	is	be	AUX
bionys-641	655	3	essential	essential	ADJ
bionys-641	655	4	for	for	ADP
bionys-641	655	5	polθ	polθ	NOUN
bionys-641	655	6	-	-	PUNCT
bionys-641	655	7	mediated	mediate	VERB
bionys-641	655	8	dna	dna	NOUN
bionys-641	655	9	end	end	NOUN
bionys-641	655	10	-	-	PUNCT
bionys-641	655	11	joining	join	VERB
bionys-641	655	12	by	by	ADP
bionys-641	655	13	removing	remove	VERB
bionys-641	655	14	repressive	repressive	ADJ
bionys-641	655	15	polyadp	polyadp	ADJ
bionys-641	655	16	-	-	ADJ
bionys-641	655	17	ribose	ribose	ADJ
bionys-641	655	18	marks	mark	NOUN
bionys-641	655	19	.	.	PUNCT
bionys-641	656	1	nature	nature	NOUN
bionys-641	656	2	communications	communication	NOUN
bionys-641	656	3	,	,	PUNCT
bionys-641	656	4	15(1	15(1	NUM
bionys-641	656	5	)	)	PUNCT
bionys-641	656	6	,	,	PUNCT
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bionys-641	656	8	.	.	PUNCT
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bionys-641	657	3	,	,	PUNCT
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bionys-641	657	5	.	.	PROPN
bionys-641	657	6	,	,	PUNCT
bionys-641	657	7	heuberger	heuberger	NOUN
bionys-641	657	8	,	,	PUNCT
bionys-641	657	9	j.a.a.c	j.a.a.c	PROPN
bionys-641	657	10	.	.	PROPN
bionys-641	657	11	,	,	PUNCT
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bionys-641	657	13	,	,	PUNCT
bionys-641	657	14	g.j	g.j	PROPN
bionys-641	657	15	.	.	PROPN
bionys-641	657	16	,	,	PUNCT
bionys-641	657	17	oude	oude	PROPN
bionys-641	657	18	nijhuis	nijhuis	PROPN
bionys-641	657	19	,	,	PUNCT
bionys-641	657	20	j.	j.	PROPN
bionys-641	657	21	,	,	PUNCT
bionys-641	657	22	de	de	X
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bionys-641	657	24	,	,	PUNCT
bionys-641	657	25	p.p	p.p	PROPN
bionys-641	657	26	.	.	PROPN
bionys-641	657	27	,	,	PUNCT
bionys-641	657	28	hadi	hadi	PROPN
bionys-641	657	29	,	,	PUNCT
bionys-641	657	30	s.	s.	PROPN
bionys-641	657	31	,	,	PUNCT
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bionys-641	657	33	,	,	PUNCT
bionys-641	657	34	j.	j.	PROPN
bionys-641	657	35	,	,	PUNCT
bionys-641	657	36	tsai	tsai	PROPN
bionys-641	657	37	,	,	PUNCT
bionys-641	657	38	r.m	r.m	PROPN
bionys-641	657	39	.	.	PROPN
bionys-641	657	40	,	,	PUNCT
bionys-641	657	41	cruzherranz	cruzherranz	PROPN
bionys-641	657	42	,	,	PUNCT
bionys-641	657	43	a.	a.	PROPN
bionys-641	657	44	,	,	PUNCT
bionys-641	657	45	huang	huang	PROPN
bionys-641	657	46	,	,	PUNCT
bionys-641	657	47	f.	f.	PROPN
bionys-641	657	48	,	,	PUNCT
bionys-641	657	49	tong	tong	PROPN
bionys-641	657	50	,	,	PUNCT
bionys-641	657	51	v.	v.	PROPN
bionys-641	657	52	,	,	PUNCT
bionys-641	657	53	erickson	erickson	PROPN
bionys-641	657	54	,	,	PUNCT
bionys-641	657	55	r.	r.	PROPN
bionys-641	657	56	,	,	PUNCT
bionys-641	657	57	zhu	zhu	PROPN
bionys-641	657	58	,	,	PUNCT
bionys-641	657	59	y.	y.	PROPN
bionys-641	657	60	,	,	PUNCT
bionys-641	657	61	scearce	scearce	NOUN
bionys-641	657	62	-	-	PUNCT
bionys-641	657	63	levie	levie	NOUN
bionys-641	657	64	,	,	PUNCT
bionys-641	657	65	k.	k.	PROPN
bionys-641	657	66	,	,	PUNCT
bionys-641	657	67	hsiao	hsiao	PROPN
bionys-641	657	68	-	-	NOUN
bionys-641	657	69	nakamoto	nakamoto	NOUN
bionys-641	657	70	,	,	PUNCT
bionys-641	657	71	j.	j.	PROPN
bionys-641	657	72	,	,	PUNCT
bionys-641	657	73	tang	tang	PROPN
bionys-641	657	74	,	,	PUNCT
bionys-641	657	75	x.	x.	PROPN
bionys-641	657	76	,	,	PUNCT
bionys-641	657	77	chang	chang	PROPN
bionys-641	657	78	,	,	PUNCT
bionys-641	657	79	m.	m.	NOUN
bionys-641	657	80	,	,	PUNCT
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bionys-641	657	82	,	,	PUNCT
bionys-641	657	83	b.m	b.m	PROPN
bionys-641	657	84	.	.	PROPN
bionys-641	657	85	,	,	PUNCT
bionys-641	657	86	estrada	estrada	PROPN
bionys-641	657	87	,	,	PUNCT
bionys-641	657	88	a.a	a.a	PROPN
bionys-641	657	89	.	.	PROPN
bionys-641	657	90	,	,	PUNCT
bionys-641	657	91	pomponio	pomponio	PROPN
bionys-641	657	92	,	,	PUNCT
bionys-641	657	93	r.j	r.j	PROPN
bionys-641	657	94	.	.	PROPN
bionys-641	657	95	,	,	PUNCT
bionys-641	657	96	alonso	alonso	NOUN
bionys-641	657	97	-	-	PUNCT
bionys-641	657	98	alonso	alonso	NOUN
bionys-641	657	99	,	,	PUNCT
bionys-641	657	100	m.	m.	NOUN
bionys-641	657	101	,	,	PUNCT
bionys-641	657	102	zilberstein	zilberstein	PROPN
bionys-641	657	103	,	,	PUNCT
bionys-641	657	104	m.	m.	NOUN
bionys-641	657	105	,	,	PUNCT
bionys-641	657	106	atassi	atassi	ADJ
bionys-641	657	107	,	,	PUNCT
bionys-641	657	108	n.	n.	NOUN
bionys-641	657	109	,	,	PUNCT
bionys-641	657	110	troyer	troyer	PROPN
bionys-641	657	111	,	,	PUNCT
bionys-641	657	112	m.d	m.d	PROPN
bionys-641	657	113	.	.	PROPN
bionys-641	657	114	,	,	PUNCT
bionys-641	657	115	&	&	CCONJ
bionys-641	657	116	ho	ho	PROPN
bionys-641	657	117	,	,	PUNCT
bionys-641	657	118	c.	c.	PROPN
bionys-641	657	119	(	(	PUNCT
bionys-641	657	120	2022	2022	NUM
bionys-641	657	121	)	)	PUNCT
bionys-641	657	122	.	.	PUNCT
bionys-641	658	1	safety	safety	NOUN
bionys-641	658	2	,	,	PUNCT
bionys-641	658	3	pharmacokinetics	pharmacokinetic	NOUN
bionys-641	658	4	and	and	CCONJ
bionys-641	658	5	target	target	NOUN
bionys-641	658	6	engagement	engagement	NOUN
bionys-641	658	7	of	of	ADP
bionys-641	658	8	novel	novel	ADJ
bionys-641	658	9	ripk1	ripk1	NOUN
bionys-641	658	10	inhibitor	inhibitor	NOUN
bionys-641	658	11	sar443060	sar443060	NOUN
bionys-641	658	12	(	(	PUNCT
bionys-641	658	13	dnl747	dnl747	PROPN
bionys-641	658	14	)	)	PUNCT
bionys-641	658	15	for	for	ADP
bionys-641	658	16	neurodegenerative	neurodegenerative	ADJ
bionys-641	658	17	disorders	disorder	NOUN
bionys-641	658	18	:	:	PUNCT
bionys-641	658	19	randomized	randomize	VERB
bionys-641	658	20	,	,	PUNCT
bionys-641	658	21	placebocontrolled	placebocontrolle	VERB
bionys-641	658	22	,	,	PUNCT
bionys-641	658	23	double	double	ADJ
bionys-641	658	24	-	-	PUNCT
bionys-641	658	25	blind	blind	ADJ
bionys-641	658	26	phase	phase	NOUN
bionys-641	658	27	i	i	PRON
bionys-641	658	28	/	/	SYM
bionys-641	658	29	ib	ib	PROPN
bionys-641	658	30	studies	study	NOUN
bionys-641	658	31	in	in	ADP
bionys-641	658	32	healthy	healthy	ADJ
bionys-641	658	33	subjects	subject	NOUN
bionys-641	658	34	and	and	CCONJ
bionys-641	658	35	patients	patient	NOUN
bionys-641	658	36	.	.	PUNCT
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bionys-641	659	2	and	and	CCONJ
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bionys-641	659	4	science	science	NOUN
bionys-641	659	5	,	,	PUNCT
bionys-641	659	6	15(8	15(8	NOUN
bionys-641	659	7	)	)	PUNCT
bionys-641	659	8	,	,	PUNCT
bionys-641	659	9	2010–2023	2010–2023	NUM
bionys-641	659	10	.	.	PUNCT
bionys-641	660	1	https://doi.org/10.1111/	https://doi.org/10.1111/	PROPN
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bionys-641	660	3	wagatsuma	wagatsuma	NOUN
bionys-641	660	4	,	,	PUNCT
bionys-641	660	5	k.	k.	PROPN
bionys-641	660	6	&	&	CCONJ
bionys-641	660	7	nakase	nakase	PROPN
bionys-641	660	8	,	,	PUNCT
bionys-641	660	9	h.	h.	PROPN
bionys-641	660	10	(	(	PUNCT
bionys-641	660	11	2020	2020	NUM
bionys-641	660	12	)	)	PUNCT
bionys-641	660	13	.	.	PUNCT
bionys-641	661	1	contradictory	contradictory	ADJ
bionys-641	661	2	effects	effect	NOUN
bionys-641	661	3	of	of	ADP
bionys-641	661	4	nlrp3	nlrp3	NOUN
bionys-641	661	5	inflammasome	inflammasome	VERB
bionys-641	661	6	regulatory	regulatory	ADJ
bionys-641	661	7	mechanisms	mechanism	NOUN
bionys-641	661	8	in	in	ADP
bionys-641	661	9	colitis	colitis	NOUN
bionys-641	661	10	.	.	PUNCT
bionys-641	662	1	international	international	ADJ
bionys-641	662	2	journal	journal	NOUN
bionys-641	662	3	of	of	ADP
bionys-641	662	4	molecular	molecular	ADJ
bionys-641	662	5	sciences	science	NOUN
bionys-641	662	6	,	,	PUNCT
bionys-641	662	7	21(21	21(21	NUM
bionys-641	662	8	)	)	PUNCT
bionys-641	662	9	,	,	PUNCT
bionys-641	662	10	8145	8145	NUM
bionys-641	662	11	.	.	PUNCT
bionys-641	663	1	https://doi	https://doi	X
bionys-641	663	2	.	.	PUNCT
bionys-641	663	3	org/10.3390	org/10.3390	PROPN
bionys-641	663	4	/	/	SYM
bionys-641	663	5	ijms21218145	ijms21218145	PROPN
bionys-641	663	6	wang	wang	PROPN
bionys-641	663	7	,	,	PUNCT
bionys-641	663	8	y.	y.	PROPN
bionys-641	663	9	,	,	PUNCT
bionys-641	663	10	kim	kim	PROPN
bionys-641	663	11	,	,	PUNCT
bionys-641	663	12	n.s	n.s	PROPN
bionys-641	663	13	.	.	PROPN
bionys-641	663	14	,	,	PUNCT
bionys-641	663	15	haince	haince	NOUN
bionys-641	663	16	,	,	PUNCT
bionys-641	663	17	j.-f	j.-f	PROPN
bionys-641	663	18	.	.	PUNCT
bionys-641	663	19	,	,	PUNCT
bionys-641	663	20	kang	kang	PROPN
bionys-641	663	21	,	,	PUNCT
bionys-641	663	22	h.c	h.c	PROPN
bionys-641	663	23	.	.	PROPN
bionys-641	663	24	,	,	PUNCT
bionys-641	663	25	david	david	PROPN
bionys-641	663	26	,	,	PUNCT
bionys-641	663	27	k.k	k.k	PROPN
bionys-641	663	28	.	.	PROPN
bionys-641	663	29	,	,	PUNCT
bionys-641	663	30	andrabi	andrabi	NOUN
bionys-641	663	31	,	,	PUNCT
bionys-641	663	32	s.a	s.a	PROPN
bionys-641	663	33	.	.	PROPN
bionys-641	663	34	,	,	PUNCT
bionys-641	663	35	poirier	poirier	PROPN
bionys-641	663	36	,	,	PUNCT
bionys-641	663	37	g.g	g.g	PROPN
bionys-641	663	38	.	.	PROPN
bionys-641	663	39	,	,	PUNCT
bionys-641	663	40	dawson	dawson	PROPN
bionys-641	663	41	,	,	PUNCT
bionys-641	663	42	v.l	v.l	PROPN
bionys-641	663	43	.	.	PROPN
bionys-641	663	44	,	,	PUNCT
bionys-641	663	45	&	&	CCONJ
bionys-641	663	46	dawson	dawson	PROPN
bionys-641	663	47	,	,	PUNCT
bionys-641	663	48	t.m	t.m	PROPN
bionys-641	663	49	.	.	PROPN
bionys-641	663	50	(	(	PUNCT
bionys-641	663	51	2011	2011	NUM
bionys-641	663	52	)	)	PUNCT
bionys-641	663	53	.	.	PUNCT
bionys-641	664	1	poly(adpribose	poly(adpribose	PROPN
bionys-641	664	2	)	)	PUNCT
bionys-641	664	3	(	(	PUNCT
bionys-641	664	4	par	par	NOUN
bionys-641	664	5	)	)	PUNCT
bionys-641	664	6	binding	bind	VERB
bionys-641	664	7	to	to	ADP
bionys-641	664	8	apoptosis	apoptosis	NOUN
bionys-641	664	9	-	-	PUNCT
bionys-641	664	10	inducing	induce	VERB
bionys-641	664	11	factor	factor	NOUN
bionys-641	664	12	is	be	AUX
bionys-641	664	13	critical	critical	ADJ
bionys-641	664	14	for	for	ADP
bionys-641	664	15	par	par	NOUN
bionys-641	664	16	polymerase-1	polymerase-1	PROPN
bionys-641	664	17	-	-	PUNCT
bionys-641	664	18	dependent	dependent	ADJ
bionys-641	664	19	cell	cell	NOUN
bionys-641	664	20	death	death	NOUN
bionys-641	664	21	(	(	PUNCT
bionys-641	664	22	parthanatos	parthanatos	NOUN
bionys-641	664	23	)	)	PUNCT
bionys-641	664	24	.	.	PUNCT
bionys-641	665	1	science	science	NOUN
bionys-641	665	2	signaling	signaling	NOUN
bionys-641	665	3	,	,	PUNCT
bionys-641	665	4	4(167	4(167	NUM
bionys-641	665	5	)	)	PUNCT
bionys-641	665	6	,	,	PUNCT
bionys-641	665	7	ra20	ra20	PROPN
bionys-641	665	8	.	.	PUNCT
bionys-641	666	1	https://doi.org/10.1126/scisignal.2000902	https://doi.org/10.1126/scisignal.2000902	PROPN
bionys-641	666	2	weiß	weiß	PROPN
bionys-641	666	3	,	,	PUNCT
bionys-641	666	4	j.	j.	PROPN
bionys-641	666	5	,	,	PUNCT
bionys-641	666	6	heib	heib	NOUN
bionys-641	666	7	,	,	PUNCT
bionys-641	666	8	m.	m.	NOUN
bionys-641	666	9	,	,	PUNCT
bionys-641	666	10	korn	korn	PROPN
bionys-641	666	11	,	,	PUNCT
bionys-641	666	12	t.	t.	PROPN
bionys-641	666	13	,	,	PUNCT
bionys-641	666	14	hoyer	hoyer	PROPN
bionys-641	666	15	,	,	PUNCT
bionys-641	666	16	j.	j.	PROPN
bionys-641	666	17	,	,	PUNCT
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bionys-641	666	20	,	,	PUNCT
bionys-641	666	21	j.	j.	PROPN
bionys-641	666	22	,	,	PUNCT
bionys-641	666	23	voigt	voigt	PROPN
bionys-641	666	24	,	,	PUNCT
bionys-641	666	25	s.	s.	PROPN
bionys-641	666	26	,	,	PUNCT
bionys-641	666	27	koudelka	koudelka	PROPN
bionys-641	666	28	,	,	PUNCT
bionys-641	666	29	t.	t.	PROPN
bionys-641	666	30	,	,	PUNCT
bionys-641	666	31	tholey	tholey	NOUN
bionys-641	666	32	,	,	PUNCT
bionys-641	666	33	a.	a.	NOUN
bionys-641	666	34	,	,	PUNCT
bionys-641	666	35	&	&	CCONJ
bionys-641	666	36	adam	adam	PROPN
bionys-641	666	37	,	,	PUNCT
bionys-641	666	38	d.	d.	PROPN
bionys-641	666	39	(	(	PUNCT
bionys-641	666	40	2023	2023	NUM
bionys-641	666	41	)	)	PUNCT
bionys-641	666	42	.	.	PUNCT
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bionys-641	667	2	-	-	PUNCT
bionys-641	667	3	independent	independent	ADJ
bionys-641	667	4	control	control	NOUN
bionys-641	667	5	of	of	ADP
bionys-641	667	6	parthanatos	parthanato	NOUN
bionys-641	667	7	by	by	ADP
bionys-641	667	8	htra2	htra2	PROPN
bionys-641	667	9	/	/	SYM
bionys-641	667	10	omi	omi	PROPN
bionys-641	667	11	.	.	PUNCT
bionys-641	667	12	cellular	cellular	ADJ
bionys-641	667	13	and	and	CCONJ
bionys-641	667	14	molecular	molecular	ADJ
bionys-641	667	15	life	life	NOUN
bionys-641	667	16	sciences	science	NOUN
bionys-641	667	17	,	,	PUNCT
bionys-641	667	18	80(9	80(9	NUM
bionys-641	667	19	)	)	PUNCT
bionys-641	667	20	,	,	PUNCT
bionys-641	667	21	258	258	NUM
bionys-641	667	22	.	.	PUNCT
bionys-641	668	1	https://doi.org/10.1007/	https://doi.org/10.1007/	PROPN
bionys-641	668	2	s00018	s00018	PROPN
bionys-641	668	3	-	-	PUNCT
bionys-641	668	4	023	023	NUM
bionys-641	668	5	-	-	PUNCT
bionys-641	668	6	04904	04904	NUM
bionys-641	668	7	-	-	PUNCT
bionys-641	668	8	7	7	NUM
bionys-641	668	9	whitfield	whitfield	NOUN
bionys-641	668	10	,	,	PUNCT
bionys-641	668	11	m.l	m.l	PROPN
bionys-641	668	12	.	.	PROPN
bionys-641	668	13	,	,	PUNCT
bionys-641	668	14	sherlock	sherlock	PROPN
bionys-641	668	15	,	,	PUNCT
bionys-641	668	16	g.	g.	PROPN
bionys-641	668	17	,	,	PUNCT
bionys-641	668	18	saldanha	saldanha	NOUN
bionys-641	668	19	,	,	PUNCT
bionys-641	668	20	a.j	a.j	PROPN
bionys-641	668	21	.	.	PROPN
bionys-641	668	22	,	,	PUNCT
bionys-641	668	23	murray	murray	PROPN
bionys-641	668	24	,	,	PUNCT
bionys-641	668	25	j.i	j.i	PROPN
bionys-641	668	26	.	.	PROPN
bionys-641	668	27	,	,	PUNCT
bionys-641	668	28	ball	ball	PROPN
bionys-641	668	29	,	,	PUNCT
bionys-641	668	30	c.a	c.a	PROPN
bionys-641	668	31	.	.	PROPN
bionys-641	668	32	,	,	PUNCT
bionys-641	668	33	alexander	alexander	PROPN
bionys-641	668	34	,	,	PUNCT
bionys-641	668	35	k.e	k.e	PROPN
bionys-641	668	36	.	.	PROPN
bionys-641	668	37	,	,	PUNCT
bionys-641	668	38	matese	matese	PROPN
bionys-641	668	39	,	,	PUNCT
bionys-641	668	40	j.c	j.c	PROPN
bionys-641	668	41	.	.	PROPN
bionys-641	668	42	,	,	PUNCT
bionys-641	668	43	perou	perou	NOUN
bionys-641	668	44	,	,	PUNCT
bionys-641	668	45	c.m	c.m	PROPN
bionys-641	668	46	.	.	PROPN
bionys-641	668	47	,	,	PUNCT
bionys-641	668	48	hurt	hurt	VERB
bionys-641	668	49	,	,	PUNCT
bionys-641	668	50	m.m	m.m	PROPN
bionys-641	668	51	.	.	PROPN
bionys-641	668	52	,	,	PUNCT
bionys-641	668	53	brown	brown	PROPN
bionys-641	668	54	,	,	PUNCT
bionys-641	668	55	p.o	p.o	PROPN
bionys-641	668	56	.	.	PROPN
bionys-641	668	57	,	,	PUNCT
bionys-641	668	58	&	&	CCONJ
bionys-641	668	59	botstein	botstein	PROPN
bionys-641	668	60	,	,	PUNCT
bionys-641	668	61	d.	d.	PROPN
bionys-641	668	62	(	(	PUNCT
bionys-641	668	63	2002	2002	NUM
bionys-641	668	64	)	)	PUNCT
bionys-641	668	65	.	.	PUNCT
bionys-641	669	1	identification	identification	NOUN
bionys-641	669	2	of	of	ADP
bionys-641	669	3	genes	gene	NOUN
bionys-641	669	4	periodically	periodically	ADV
bionys-641	669	5	expressed	express	VERB
bionys-641	669	6	in	in	ADP
bionys-641	669	7	the	the	DET
bionys-641	669	8	human	human	ADJ
bionys-641	669	9	cell	cell	NOUN
bionys-641	669	10	cycle	cycle	NOUN
bionys-641	669	11	and	and	CCONJ
bionys-641	669	12	their	their	PRON
bionys-641	669	13	expression	expression	NOUN
bionys-641	669	14	in	in	ADP
bionys-641	669	15	tumors	tumor	NOUN
bionys-641	669	16	.	.	PUNCT
bionys-641	670	1	molecular	molecular	ADJ
bionys-641	670	2	biology	biology	NOUN
bionys-641	670	3	of	of	ADP
bionys-641	670	4	the	the	DET
bionys-641	670	5	cell	cell	NOUN
bionys-641	670	6	,	,	PUNCT
bionys-641	670	7	13(6	13(6	PROPN
bionys-641	670	8	)	)	PUNCT
bionys-641	670	9	,	,	PUNCT
bionys-641	670	10	1977–2000	1977–2000	NUM
bionys-641	670	11	.	.	PUNCT
bionys-641	671	1	https://doi.org/10.1091/	https://doi.org/10.1091/	PROPN
bionys-641	671	2	mbc.02	mbc.02	PROPN
bionys-641	671	3	-	-	PUNCT
bionys-641	671	4	02	02	NUM
bionys-641	671	5	-	-	PUNCT
bionys-641	671	6	0030	0030	NUM
bionys-641	671	7	xu	xu	PROPN
bionys-641	671	8	,	,	PUNCT
bionys-641	671	9	m.	m.	NOUN
bionys-641	671	10	,	,	PUNCT
bionys-641	671	11	zhang	zhang	PROPN
bionys-641	671	12	,	,	PUNCT
bionys-641	671	13	d.	d.	PROPN
bionys-641	671	14	,	,	PUNCT
bionys-641	671	15	&	&	CCONJ
bionys-641	671	16	yan	yan	PROPN
bionys-641	671	17	,	,	PUNCT
bionys-641	671	18	j.	j.	PROPN
bionys-641	671	19	(	(	PUNCT
bionys-641	671	20	2024	2024	NUM
bionys-641	671	21	)	)	PUNCT
bionys-641	671	22	.	.	PUNCT
bionys-641	672	1	targeting	target	VERB
bionys-641	672	2	ferroptosis	ferroptosis	NOUN
bionys-641	672	3	using	use	VERB
bionys-641	672	4	chinese	chinese	ADJ
bionys-641	672	5	herbal	herbal	ADJ
bionys-641	672	6	compounds	compound	NOUN
bionys-641	672	7	to	to	PART
bionys-641	672	8	treat	treat	VERB
bionys-641	672	9	respiratory	respiratory	ADJ
bionys-641	672	10	diseases	disease	NOUN
bionys-641	672	11	.	.	PUNCT
bionys-641	673	1	phytomedicine	phytomedicine	NOUN
bionys-641	673	2	,	,	PUNCT
bionys-641	673	3	130	130	NUM
bionys-641	673	4	,	,	PUNCT
bionys-641	673	5	155738	155738	NUM
bionys-641	673	6	.	.	PUNCT
bionys-641	674	1	https://doi.org/10.1016/j.phymed.2024.155738	https://doi.org/10.1016/j.phymed.2024.155738	PROPN
bionys-641	674	2	ye	ye	PRON
bionys-641	674	3	,	,	PUNCT
bionys-641	674	4	k.	k.	PROPN
bionys-641	674	5	,	,	PUNCT
bionys-641	674	6	chen	chen	PROPN
bionys-641	674	7	,	,	PUNCT
bionys-641	674	8	z.	z.	PROPN
bionys-641	674	9	,	,	PUNCT
bionys-641	674	10	&	&	CCONJ
bionys-641	674	11	xu	xu	PROPN
bionys-641	674	12	,	,	PUNCT
bionys-641	674	13	y.	y.	PROPN
bionys-641	674	14	(	(	PUNCT
bionys-641	674	15	2023	2023	NUM
bionys-641	674	16	)	)	PUNCT
bionys-641	674	17	.	.	PUNCT
bionys-641	675	1	the	the	DET
bionys-641	675	2	doubleedged	doubleedge	VERB
bionys-641	675	3	functions	function	NOUN
bionys-641	675	4	of	of	ADP
bionys-641	675	5	necroptosis	necroptosis	NOUN
bionys-641	675	6	.	.	PUNCT
bionys-641	676	1	cell	cell	NOUN
bionys-641	676	2	death	death	NOUN
bionys-641	676	3	&	&	CCONJ
bionys-641	676	4	disease	disease	PROPN
bionys-641	676	5	,	,	PUNCT
bionys-641	676	6	14(2	14(2	NUM
bionys-641	676	7	)	)	PUNCT
bionys-641	676	8	,	,	PUNCT
bionys-641	676	9	163	163	NUM
bionys-641	676	10	.	.	PUNCT
bionys-641	677	1	https://doi.org/10.1038/s41419023-05691-6	https://doi.org/10.1038/s41419023-05691-6	PROPN
bionys-641	677	2	zhang	zhang	PROPN
bionys-641	677	3	,	,	PUNCT
bionys-641	677	4	g.	g.	PROPN
bionys-641	677	5	,	,	PUNCT
bionys-641	677	6	yao	yao	PROPN
bionys-641	677	7	,	,	PUNCT
bionys-641	677	8	y.	y.	PROPN
bionys-641	677	9	,	,	PUNCT
bionys-641	677	10	zhang	zhang	PROPN
bionys-641	677	11	,	,	PUNCT
bionys-641	677	12	z.	z.	PROPN
bionys-641	677	13	,	,	PUNCT
bionys-641	677	14	xiao	xiao	PROPN
bionys-641	677	15	,	,	PUNCT
bionys-641	677	16	j.	j.	PROPN
bionys-641	677	17	,	,	PUNCT
bionys-641	677	18	yu	yu	PROPN
bionys-641	677	19	,	,	PUNCT
bionys-641	677	20	h.	h.	PROPN
bionys-641	677	21	,	,	PUNCT
bionys-641	677	22	zhao	zhao	PROPN
bionys-641	677	23	,	,	PUNCT
bionys-641	677	24	j.	j.	PROPN
bionys-641	677	25	,	,	PUNCT
bionys-641	677	26	yao	yao	PROPN
bionys-641	677	27	,	,	PUNCT
bionys-641	677	28	c.	c.	PROPN
bionys-641	677	29	,	,	PUNCT
bionys-641	677	30	wang	wang	PROPN
bionys-641	677	31	,	,	PUNCT
bionys-641	677	32	y.	y.	PROPN
bionys-641	677	33	,	,	PUNCT
bionys-641	677	34	&	&	CCONJ
bionys-641	677	35	luo	luo	PROPN
bionys-641	677	36	,	,	PUNCT
bionys-641	677	37	h.	h.	PROPN
bionys-641	677	38	(	(	PUNCT
bionys-641	677	39	2024	2024	NUM
bionys-641	677	40	)	)	PUNCT
bionys-641	677	41	.	.	PUNCT
bionys-641	678	1	regulation	regulation	NOUN
bionys-641	678	2	of	of	ADP
bionys-641	678	3	nlrp3	nlrp3	ADJ
bionys-641	678	4	inflammasome	inflammasome	NOUN
bionys-641	678	5	and	and	CCONJ
bionys-641	678	6	caspase-3/4/11	caspase-3/4/11	NOUN
bionys-641	678	7	by	by	ADP
bionys-641	678	8	2′,4′-dihydroxychalcone	2′,4′-dihydroxychalcone	NUM
bionys-641	678	9	contributes	contribute	VERB
bionys-641	678	10	to	to	ADP
bionys-641	678	11	anti	anti	ADJ
bionys-641	678	12	-	-	ADJ
bionys-641	678	13	colorectal	colorectal	ADJ
bionys-641	678	14	cancer	cancer	NOUN
bionys-641	678	15	.	.	PUNCT
bionys-641	679	1	phytomedicine	phytomedicine	NOUN
bionys-641	679	2	,	,	PUNCT
bionys-641	679	3	135	135	NUM
bionys-641	679	4	,	,	PUNCT
bionys-641	679	5	156194	156194	NUM
bionys-641	679	6	.	.	PUNCT
bionys-641	680	1	https://doi.org/10.1016/j	https://doi.org/10.1016/j	NOUN
bionys-641	680	2	.	.	PUNCT
bionys-641	681	1	phymed.2024.156194	phymed.2024.156194	PROPN
bionys-641	681	2	zhang	zhang	PROPN
bionys-641	681	3	,	,	PUNCT
bionys-641	681	4	j.	j.	PROPN
bionys-641	681	5	,	,	PUNCT
bionys-641	681	6	huang	huang	PROPN
bionys-641	681	7	,	,	PUNCT
bionys-641	681	8	k.	k.	PROPN
bionys-641	681	9	,	,	PUNCT
bionys-641	681	10	o’neill	o’neill	PROPN
bionys-641	681	11	,	,	PUNCT
bionys-641	681	12	k.l	k.l	PROPN
bionys-641	681	13	.	.	PROPN
bionys-641	681	14	,	,	PUNCT
bionys-641	681	15	pang	pang	NOUN
bionys-641	681	16	,	,	PUNCT
bionys-641	681	17	x.	x.	NOUN
bionys-641	681	18	,	,	PUNCT
bionys-641	681	19	&	&	CCONJ
bionys-641	681	20	luo	luo	PROPN
bionys-641	681	21	,	,	PUNCT
bionys-641	681	22	x.	x.	NOUN
bionys-641	681	23	(	(	PUNCT
bionys-641	681	24	2016	2016	NUM
bionys-641	681	25	)	)	PUNCT
bionys-641	681	26	.	.	PUNCT
bionys-641	682	1	bax	bax	PROPN
bionys-641	682	2	/	/	SYM
bionys-641	682	3	bak	bak	PROPN
bionys-641	682	4	activation	activation	NOUN
bionys-641	682	5	in	in	ADP
bionys-641	682	6	the	the	DET
bionys-641	682	7	absence	absence	NOUN
bionys-641	682	8	of	of	ADP
bionys-641	682	9	bid	bid	NOUN
bionys-641	682	10	,	,	PUNCT
bionys-641	682	11	bim	bim	NOUN
bionys-641	682	12	,	,	PUNCT
bionys-641	682	13	puma	puma	PROPN
bionys-641	682	14	,	,	PUNCT
bionys-641	682	15	and	and	CCONJ
bionys-641	682	16	p53	p53	NOUN
bionys-641	682	17	.	.	PUNCT
bionys-641	683	1	cell	cell	NOUN
bionys-641	683	2	death	death	NOUN
bionys-641	683	3	&	&	CCONJ
bionys-641	683	4	disease	disease	PROPN
bionys-641	683	5	,	,	PUNCT
bionys-641	683	6	7(6	7(6	NUM
bionys-641	683	7	)	)	PUNCT
bionys-641	683	8	,	,	PUNCT
bionys-641	683	9	e2266	e2266	PROPN
bionys-641	683	10	.	.	PUNCT
bionys-641	684	1	https://doi.org/10.1038/cddis.2016.167	https://doi.org/10.1038/cddis.2016.167	PROPN
bionys-641	684	2	zhang	zhang	PROPN
bionys-641	684	3	,	,	PUNCT
bionys-641	684	4	y.	y.	PROPN
bionys-641	684	5	,	,	PUNCT
bionys-641	684	6	yang	yang	PROPN
bionys-641	684	7	,	,	PUNCT
bionys-641	684	8	w.	w.	PROPN
bionys-641	684	9	,	,	PUNCT
bionys-641	684	10	li	li	PROPN
bionys-641	684	11	,	,	PUNCT
bionys-641	684	12	w.	w.	PROPN
bionys-641	684	13	,	,	PUNCT
bionys-641	684	14	&	&	CCONJ
bionys-641	684	15	zhao	zhao	PROPN
bionys-641	684	16	,	,	PUNCT
bionys-641	684	17	y.	y.	PROPN
bionys-641	684	18	(	(	PUNCT
bionys-641	684	19	2021	2021	NUM
bionys-641	684	20	)	)	PUNCT
bionys-641	684	21	.	.	PUNCT
bionys-641	685	1	nlrp3	nlrp3	PROPN
bionys-641	685	2	inflammasome	inflammasome	NOUN
bionys-641	685	3	:	:	PUNCT
bionys-641	685	4	checkpoint	checkpoint	NOUN
bionys-641	685	5	connecting	connect	VERB
bionys-641	685	6	innate	innate	ADJ
bionys-641	685	7	and	and	CCONJ
bionys-641	685	8	adaptive	adaptive	ADJ
bionys-641	685	9	immunity	immunity	NOUN
bionys-641	685	10	in	in	ADP
bionys-641	685	11	autoimmune	autoimmune	ADJ
bionys-641	685	12	diseases	disease	NOUN
bionys-641	685	13	.	.	PUNCT
bionys-641	686	1	frontiers	frontier	NOUN
bionys-641	686	2	in	in	ADP
bionys-641	686	3	immunology	immunology	NOUN
bionys-641	686	4	,	,	PUNCT
bionys-641	686	5	12	12	NUM
bionys-641	686	6	,	,	PUNCT
bionys-641	686	7	732933	732933	NUM
bionys-641	686	8	.	.	PUNCT
bionys-641	687	1	https://doi.org/10.3389/fimmu.2021.732933	https://doi.org/10.3389/fimmu.2021.732933	PROPN
bionys-641	687	2	zhao	zhao	PROPN
bionys-641	687	3	,	,	PUNCT
bionys-641	687	4	q.	q.	PROPN
bionys-641	687	5	,	,	PUNCT
bionys-641	687	6	piyush	piyush	PROPN
bionys-641	687	7	,	,	PUNCT
bionys-641	687	8	t.	t.	PROPN
bionys-641	687	9	,	,	PUNCT
bionys-641	687	10	chen	chen	PROPN
bionys-641	687	11	,	,	PUNCT
bionys-641	687	12	c.	c.	PROPN
bionys-641	687	13	,	,	PUNCT
bionys-641	687	14	hollingsworth	hollingsworth	PROPN
bionys-641	687	15	,	,	PUNCT
bionys-641	687	16	m.a	m.a	PROPN
bionys-641	687	17	.	.	PROPN
bionys-641	687	18	,	,	PUNCT
bionys-641	687	19	hilkens	hilken	NOUN
bionys-641	687	20	,	,	PUNCT
bionys-641	687	21	j.	j.	PROPN
bionys-641	687	22	,	,	PUNCT
bionys-641	687	23	rhodes	rhodes	PROPN
bionys-641	687	24	,	,	PUNCT
bionys-641	687	25	j.m	j.m	PROPN
bionys-641	687	26	.	.	PROPN
bionys-641	687	27	,	,	PUNCT
bionys-641	687	28	&	&	CCONJ
bionys-641	687	29	yu	yu	PROPN
bionys-641	687	30	,	,	PUNCT
bionys-641	687	31	l.g	l.g	PROPN
bionys-641	687	32	.	.	PROPN
bionys-641	687	33	(	(	PUNCT
bionys-641	687	34	2014	2014	NUM
bionys-641	687	35	)	)	PUNCT
bionys-641	687	36	.	.	PUNCT
bionys-641	688	1	muc1	muc1	PROPN
bionys-641	688	2	extracellular	extracellular	ADJ
bionys-641	688	3	domain	domain	NOUN
bionys-641	688	4	confers	confer	NOUN
bionys-641	688	5	resistance	resistance	NOUN
bionys-641	688	6	of	of	ADP
bionys-641	688	7	epithelial	epithelial	ADJ
bionys-641	688	8	cancer	cancer	NOUN
bionys-641	688	9	cells	cell	NOUN
bionys-641	688	10	to	to	ADP
bionys-641	688	11	anoikis	anoiki	NOUN
bionys-641	688	12	.	.	PUNCT
bionys-641	689	1	cell	cell	NOUN
bionys-641	689	2	death	death	NOUN
bionys-641	689	3	&	&	CCONJ
bionys-641	689	4	disease	disease	PROPN
bionys-641	689	5	,	,	PUNCT
bionys-641	689	6	5(10	5(10	NUM
bionys-641	689	7	)	)	PUNCT
bionys-641	689	8	,	,	PUNCT
bionys-641	689	9	e1438	e1438	NOUN
bionys-641	689	10	.	.	PUNCT
bionys-641	690	1	https://doi	https://doi	PROPN
bionys-641	690	2	.	.	PUNCT
bionys-641	690	3	org/10.1038	org/10.1038	PROPN
bionys-641	690	4	/	/	SYM
bionys-641	690	5	cddis.2014.421	cddis.2014.421	PROPN
bionys-641	690	6	zhao	zhao	PROPN
bionys-641	690	7	,	,	PUNCT
bionys-641	690	8	z.	z.	PROPN
bionys-641	690	9	,	,	PUNCT
bionys-641	690	10	wijerathne	wijerathne	PROPN
bionys-641	690	11	,	,	PUNCT
bionys-641	690	12	h.	h.	PROPN
bionys-641	690	13	,	,	PUNCT
bionys-641	690	14	godwin	godwin	PROPN
bionys-641	690	15	,	,	PUNCT
bionys-641	690	16	a.k	a.k	PROPN
bionys-641	690	17	.	.	PROPN
bionys-641	690	18	,	,	PUNCT
bionys-641	690	19	&	&	CCONJ
bionys-641	690	20	soper	soper	PROPN
bionys-641	690	21	,	,	PUNCT
bionys-641	690	22	s.a	s.a	PROPN
bionys-641	690	23	.	.	PROPN
bionys-641	690	24	(	(	PUNCT
bionys-641	690	25	2021	2021	NUM
bionys-641	690	26	)	)	PUNCT
bionys-641	690	27	.	.	PUNCT
bionys-641	691	1	isolation	isolation	NOUN
bionys-641	691	2	and	and	CCONJ
bionys-641	691	3	analysis	analysis	NOUN
bionys-641	691	4	methods	method	NOUN
bionys-641	691	5	of	of	ADP
bionys-641	691	6	extracellular	extracellular	ADJ
bionys-641	691	7	vesicles	vesicle	NOUN
bionys-641	691	8	(	(	PUNCT
bionys-641	691	9	evs	evs	NOUN
bionys-641	691	10	)	)	PUNCT
bionys-641	691	11	.	.	PUNCT
bionys-641	692	1	extracellular	extracellular	ADJ
bionys-641	692	2	vesicles	vesicle	NOUN
bionys-641	692	3	and	and	CCONJ
bionys-641	692	4	circulating	circulate	VERB
bionys-641	692	5	nucleic	nucleic	ADJ
bionys-641	692	6	acids	acid	NOUN
bionys-641	692	7	,	,	PUNCT
bionys-641	692	8	2(1	2(1	NUM
bionys-641	692	9	)	)	PUNCT
bionys-641	692	10	,	,	PUNCT
bionys-641	692	11	80–103	80–103	PROPN
bionys-641	692	12	.	.	PUNCT
bionys-641	693	1	https://	https://	PROPN
bionys-641	693	2	doi.org/10.20517/evcna.2021.07	doi.org/10.20517/evcna.2021.07	PROPN
bionys-641	693	3	zhong	zhong	PROPN
bionys-641	693	4	,	,	PUNCT
bionys-641	693	5	b.	b.	PROPN
bionys-641	693	6	,	,	PUNCT
bionys-641	693	7	liu	liu	PROPN
bionys-641	693	8	,	,	PUNCT
bionys-641	693	9	m.	m.	NOUN
bionys-641	693	10	,	,	PUNCT
bionys-641	693	11	bai	bai	PROPN
bionys-641	693	12	,	,	PUNCT
bionys-641	693	13	c.	c.	PROPN
bionys-641	693	14	,	,	PUNCT
bionys-641	693	15	ruan	ruan	PROPN
bionys-641	693	16	,	,	PUNCT
bionys-641	693	17	y.	y.	PROPN
bionys-641	693	18	,	,	PUNCT
bionys-641	693	19	wang	wang	PROPN
bionys-641	693	20	,	,	PUNCT
bionys-641	693	21	y.	y.	PROPN
bionys-641	693	22	,	,	PUNCT
bionys-641	693	23	qiu	qiu	PROPN
bionys-641	693	24	,	,	PUNCT
bionys-641	693	25	l.	l.	PROPN
bionys-641	693	26	,	,	PUNCT
bionys-641	693	27	hong	hong	PROPN
bionys-641	693	28	,	,	PUNCT
bionys-641	693	29	y.	y.	PROPN
bionys-641	693	30	,	,	PUNCT
bionys-641	693	31	wang	wang	PROPN
bionys-641	693	32	,	,	PUNCT
bionys-641	693	33	x.	x.	PROPN
bionys-641	693	34	,	,	PUNCT
bionys-641	693	35	li	li	PROPN
bionys-641	693	36	,	,	PUNCT
bionys-641	693	37	l.	l.	PROPN
bionys-641	693	38	,	,	PUNCT
bionys-641	693	39	&	&	CCONJ
bionys-641	693	40	li	li	PROPN
bionys-641	693	41	,	,	PUNCT
bionys-641	693	42	b.	b.	PROPN
bionys-641	693	43	(	(	PUNCT
bionys-641	693	44	2020	2020	NUM
bionys-641	693	45	)	)	PUNCT
bionys-641	693	46	.	.	PUNCT
bionys-641	694	1	caspase-8	caspase-8	NOUN
bionys-641	694	2	induces	induce	VERB
bionys-641	694	3	lysosome	lysosome	ADJ
bionys-641	694	4	-	-	PUNCT
bionys-641	694	5	associated	associate	VERB
bionys-641	694	6	cell	cell	NOUN
bionys-641	694	7	death	death	NOUN
bionys-641	694	8	in	in	ADP
bionys-641	694	9	cancer	cancer	NOUN
bionys-641	694	10	cells	cell	NOUN
bionys-641	694	11	.	.	PUNCT
bionys-641	695	1	molecular	molecular	ADJ
bionys-641	695	2	therapy	therapy	NOUN
bionys-641	695	3	,	,	PUNCT
bionys-641	695	4	28(4	28(4	NUM
bionys-641	695	5	)	)	PUNCT
bionys-641	695	6	,	,	PUNCT
bionys-641	695	7	1078	1078	NUM
bionys-641	695	8	–	–	PUNCT
bionys-641	695	9	1091	1091	NUM
bionys-641	695	10	.	.	PUNCT
bionys-641	696	1	https://doi.org/10.1016/j.ymthe.2020.01.022	https://doi.org/10.1016/j.ymthe.2020.01.022	NOUN
bionys-641	696	2	zhu	zhu	PROPN
bionys-641	696	3	,	,	PUNCT
bionys-641	696	4	j.	j.	PROPN
bionys-641	696	5	,	,	PUNCT
bionys-641	696	6	yang	yang	PROPN
bionys-641	696	7	,	,	PUNCT
bionys-641	696	8	y.	y.	PROPN
bionys-641	696	9	,	,	PUNCT
bionys-641	696	10	&	&	CCONJ
bionys-641	696	11	wu	wu	PROPN
bionys-641	696	12	,	,	PUNCT
bionys-641	696	13	j.	j.	PROPN
bionys-641	696	14	(	(	PUNCT
bionys-641	696	15	2007	2007	NUM
bionys-641	696	16	)	)	PUNCT
bionys-641	696	17	.	.	PUNCT
bionys-641	697	1	bcl-2	bcl-2	ADJ
bionys-641	697	2	cleavages	cleavage	NOUN
bionys-641	697	3	at	at	ADP
bionys-641	697	4	two	two	NUM
bionys-641	697	5	adjacent	adjacent	ADJ
bionys-641	697	6	sites	site	NOUN
bionys-641	697	7	by	by	ADP
bionys-641	697	8	different	different	ADJ
bionys-641	697	9	caspases	caspase	NOUN
bionys-641	697	10	promote	promote	VERB
bionys-641	697	11	cisplatin	cisplatin	NOUN
bionys-641	697	12	-	-	PUNCT
bionys-641	697	13	induced	induce	VERB
bionys-641	697	14	apoptosis	apoptosis	NOUN
bionys-641	697	15	.	.	PUNCT
bionys-641	698	1	cell	cell	NOUN
bionys-641	698	2	research	research	NOUN
bionys-641	698	3	,	,	PUNCT
bionys-641	698	4	17(5	17(5	NUM
bionys-641	698	5	)	)	PUNCT
bionys-641	698	6	,	,	PUNCT
bionys-641	698	7	441–448	441–448	NUM
bionys-641	698	8	.	.	PUNCT
bionys-641	699	1	https://doi.org/10.1038/cr.2007.36	https://doi.org/10.1038/cr.2007.36	NOUN
bionys-641	699	2	zilka	zilka	NOUN
bionys-641	699	3	,	,	PUNCT
bionys-641	699	4	o.	o.	PROPN
bionys-641	699	5	,	,	PUNCT
bionys-641	699	6	shah	shah	PROPN
bionys-641	699	7	,	,	PUNCT
bionys-641	699	8	r.	r.	PROPN
bionys-641	699	9	,	,	PUNCT
bionys-641	699	10	li	li	PROPN
bionys-641	699	11	,	,	PUNCT
bionys-641	699	12	b.	b.	PROPN
bionys-641	699	13	,	,	PUNCT
bionys-641	699	14	friedmann	friedmann	PROPN
bionys-641	699	15	angeli	angeli	PROPN
bionys-641	699	16	,	,	PUNCT
bionys-641	699	17	j.p	j.p	PROPN
bionys-641	699	18	.	.	PROPN
bionys-641	699	19	,	,	PUNCT
bionys-641	699	20	griesser	griesser	NOUN
bionys-641	699	21	,	,	PUNCT
bionys-641	699	22	m.	m.	NOUN
bionys-641	699	23	,	,	PUNCT
bionys-641	699	24	conrad	conrad	PROPN
bionys-641	699	25	,	,	PUNCT
bionys-641	699	26	m.	m.	NOUN
bionys-641	699	27	,	,	PUNCT
bionys-641	699	28	&	&	CCONJ
bionys-641	699	29	pratt	pratt	PROPN
bionys-641	699	30	,	,	PUNCT
bionys-641	699	31	d.a	d.a	PROPN
bionys-641	699	32	.	.	PROPN
bionys-641	699	33	(	(	PUNCT
bionys-641	699	34	2017	2017	NUM
bionys-641	699	35	)	)	PUNCT
bionys-641	699	36	.	.	PUNCT
bionys-641	700	1	on	on	ADP
bionys-641	700	2	the	the	DET
bionys-641	700	3	mechanism	mechanism	NOUN
bionys-641	700	4	of	of	ADP
bionys-641	700	5	cytoprotection	cytoprotection	NOUN
bionys-641	700	6	by	by	ADP
bionys-641	700	7	ferrostatin-1	ferrostatin-1	PROPN
bionys-641	700	8	and	and	CCONJ
bionys-641	700	9	liproxstatin-1	liproxstatin-1	PROPN
bionys-641	700	10	and	and	CCONJ
bionys-641	700	11	the	the	DET
bionys-641	700	12	role	role	NOUN
bionys-641	700	13	of	of	ADP
bionys-641	700	14	lipid	lipid	ADJ
bionys-641	700	15	peroxidation	peroxidation	NOUN
bionys-641	700	16	in	in	ADP
bionys-641	700	17	ferroptotic	ferroptotic	ADJ
bionys-641	700	18	cell	cell	NOUN
bionys-641	700	19	death	death	NOUN
bionys-641	700	20	.	.	PUNCT
bionys-641	701	1	acs	acs	PROPN
bionys-641	701	2	central	central	PROPN
bionys-641	701	3	science	science	NOUN
bionys-641	701	4	,	,	PUNCT
bionys-641	701	5	3(3	3(3	NUM
bionys-641	701	6	)	)	PUNCT
bionys-641	701	7	,	,	PUNCT
bionys-641	701	8	232–243	232–243	NUM
bionys-641	701	9	.	.	PUNCT
bionys-641	702	1	https://doi	https://doi	PROPN
bionys-641	702	2	.	.	PUNCT
bionys-641	702	3	org/10.1021	org/10.1021	NOUN
bionys-641	702	4	/	/	SYM
bionys-641	702	5	acscentsci.7b00028	acscentsci.7b00028	ADJ
bionys-641	702	6	zychlinsky	zychlinsky	PROPN
bionys-641	702	7	,	,	PUNCT
bionys-641	702	8	a.	a.	PROPN
bionys-641	702	9	,	,	PUNCT
bionys-641	702	10	prevost	prevost	PROPN
bionys-641	702	11	,	,	PUNCT
bionys-641	702	12	m.c	m.c	PROPN
bionys-641	702	13	.	.	PROPN
bionys-641	702	14	,	,	PUNCT
bionys-641	702	15	&	&	CCONJ
bionys-641	702	16	sansonetti	sansonetti	PROPN
bionys-641	702	17	,	,	PUNCT
bionys-641	702	18	p.j	p.j	PROPN
bionys-641	702	19	.	.	PROPN
bionys-641	702	20	(	(	PUNCT
bionys-641	702	21	1992	1992	NUM
bionys-641	702	22	)	)	PUNCT
bionys-641	702	23	.	.	PUNCT
bionys-641	703	1	shigella	shigella	PROPN
bionys-641	703	2	flexneri	flexneri	PROPN
bionys-641	703	3	induces	induce	VERB
bionys-641	703	4	apoptosis	apoptosis	NOUN
bionys-641	703	5	in	in	ADP
bionys-641	703	6	infected	infect	VERB
bionys-641	703	7	macrophages	macrophage	NOUN
bionys-641	703	8	.	.	PUNCT
bionys-641	704	1	nature	nature	NOUN
bionys-641	704	2	,	,	PUNCT
bionys-641	704	3	358(6382	358(6382	NUM
bionys-641	704	4	)	)	PUNCT
bionys-641	704	5	,	,	PUNCT
bionys-641	704	6	167–169	167–169	NUM
bionys-641	704	7	.	.	PUNCT
bionys-641	704	8	https://doi.org/10.1038/358167a0	https://doi.org/10.1038/358167a0	X