id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
biomedich-578	Saputri, Legis Ocktaviana; Harahap, Herpan Syafii; Rivarti, Arina Windri; Zubaidi, Fitriannisa Faradina	Prospecting Marine Natural Products as the Disease-Modifying Treatment of Alzheimer’s Diseases	2024	10	.pdf	application/pdf	5669	324	43	AD therapies that have been used and approved by the U.S. Food and Drug Administration (FDA) are acetylcholinesterase inhibitors (AChEIs) (such as donepezil, rivastigmine, and galantamine) and N-methyl- D-aspartate (NMDA) receptor antagonist (memantine), which only aim to improve AD symptoms (Li et al., 2019; Cummings et al., 2019; Kim et al., 2022). Reduce Aβ Clams - Anomalocardia brasiliana - Tivela mactroides - Donax striatus - Tapes phlippinarum Scallop Nodipecten nodosus Sand dollar Mellita quinquisperforata Crabs - Goniopsis cruentata - Ucides cordatus Cockle Cerastoderma edule Sea cucumber Acaudina molpadioides Mixture of glycosphingolipids Reduce Aβ1–42 peptide White leg shrimp Litopenaeus vannamei Natural Glycosaminoglicans: - Chondroitin sulphate - Heparan sulfate - Dermatan sulphate Inhibit BACE-1 Bryozoa Bugula neritina Bryostatin-1 (Macrolide lactone) - Modulate PKCε -	cache/biomedich-578.pdf	txt/biomedich-578.txt