id	sid	tid	token	lemma	pos
biomedich-1001	1	1	biology	biology	NOUN
biomedich-1001	1	2	,	,	PUNCT
biomedich-1001	1	3	medicine	medicine	NOUN
biomedich-1001	1	4	,	,	PUNCT
biomedich-1001	1	5	&	&	CCONJ
biomedich-1001	1	6	natural	natural	ADJ
biomedich-1001	1	7	product	product	NOUN
biomedich-1001	1	8	chemistry	chemistry	NOUN
biomedich-1001	1	9	issn	issn	VERB
biomedich-1001	1	10	2089	2089	NUM
biomedich-1001	1	11	-	-	SYM
biomedich-1001	1	12	6514	6514	NUM
biomedich-1001	1	13	(	(	PUNCT
biomedich-1001	1	14	paper	paper	NOUN
biomedich-1001	1	15	)	)	PUNCT
biomedich-1001	1	16	volume	volume	NOUN
biomedich-1001	1	17	14	14	NUM
biomedich-1001	1	18	,	,	PUNCT
biomedich-1001	1	19	number	number	NOUN
biomedich-1001	1	20	2	2	NUM
biomedich-1001	1	21	,	,	PUNCT
biomedich-1001	1	22	october	october	PROPN
biomedich-1001	1	23	2025	2025	NUM
biomedich-1001	1	24	|	|	ADV
biomedich-1001	1	25	pages	page	NOUN
biomedich-1001	1	26	:	:	PUNCT
biomedich-1001	1	27	1247	1247	NUM
biomedich-1001	1	28	-	-	SYM
biomedich-1001	1	29	1256	1256	NUM
biomedich-1001	1	30	|	|	ADV
biomedich-1001	1	31	doi	doi	NOUN
biomedich-1001	1	32	:	:	PUNCT
biomedich-1001	1	33	10.14421	10.14421	NUM
biomedich-1001	1	34	/	/	SYM
biomedich-1001	1	35	biomedich.2025.142.1247	biomedich.2025.142.1247	NOUN
biomedich-1001	1	36	-	-	PUNCT
biomedich-1001	1	37	1256	1256	NUM
biomedich-1001	1	38	issn	issn	PROPN
biomedich-1001	1	39	2540	2540	NUM
biomedich-1001	1	40	-	-	SYM
biomedich-1001	1	41	9328	9328	NUM
biomedich-1001	1	42	(	(	PUNCT
biomedich-1001	1	43	online	online	ADJ
biomedich-1001	1	44	)	)	PUNCT
biomedich-1001	1	45	molecular	molecular	ADJ
biomedich-1001	1	46	dynamic	dynamic	ADJ
biomedich-1001	1	47	study	study	NOUN
biomedich-1001	1	48	of	of	ADP
biomedich-1001	1	49	java	java	PROPN
biomedich-1001	1	50	cardamom	cardamom	PROPN
biomedich-1001	1	51	(	(	PUNCT
biomedich-1001	1	52	wurfbania	wurfbania	PROPN
biomedich-1001	1	53	compacta	compacta	NOUN
biomedich-1001	1	54	)	)	PUNCT
biomedich-1001	1	55	leaf	leaf	NOUN
biomedich-1001	1	56	compounds	compound	NOUN
biomedich-1001	1	57	targeting	target	VERB
biomedich-1001	1	58	xanthine	xanthine	NOUN
biomedich-1001	1	59	oxidase	oxidase	NOUN
biomedich-1001	1	60	for	for	ADP
biomedich-1001	1	61	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	1	62	ali	ali	PROPN
biomedich-1001	1	63	nofriyaldi1	nofriyaldi1	PROPN
biomedich-1001	1	64	*	*	PROPN
biomedich-1001	1	65	,	,	PUNCT
biomedich-1001	1	66	nitya	nitya	PROPN
biomedich-1001	1	67	nurul	nurul	NOUN
biomedich-1001	1	68	fadilah1	fadilah1	PROPN
biomedich-1001	1	69	,	,	PUNCT
biomedich-1001	1	70	selvy	selvy	ADJ
biomedich-1001	1	71	isnaeni2	isnaeni2	ADJ
biomedich-1001	1	72	1pharmacy	1pharmacy	NUM
biomedich-1001	1	73	department	department	NOUN
biomedich-1001	1	74	,	,	PUNCT
biomedich-1001	1	75	faculty	faculty	NOUN
biomedich-1001	1	76	of	of	ADP
biomedich-1001	1	77	health	health	NOUN
biomedich-1001	1	78	science	science	NOUN
biomedich-1001	1	79	,	,	PUNCT
biomedich-1001	1	80	perjuangan	perjuangan	PROPN
biomedich-1001	1	81	tasikmalaya	tasikmalaya	PROPN
biomedich-1001	1	82	university	university	NOUN
biomedich-1001	1	83	,	,	PUNCT
biomedich-1001	1	84	2agrotechnolgy	2agrotechnolgy	NUM
biomedich-1001	1	85	departement	departement	NOUN
biomedich-1001	1	86	,	,	PUNCT
biomedich-1001	1	87	faculty	faculty	NOUN
biomedich-1001	1	88	of	of	ADP
biomedich-1001	1	89	agriculture	agriculture	NOUN
biomedich-1001	1	90	,	,	PUNCT
biomedich-1001	1	91	perjuangan	perjuangan	PROPN
biomedich-1001	1	92	tasikmalaya	tasikmalaya	PROPN
biomedich-1001	1	93	university	university	PROPN
biomedich-1001	1	94	jl	jl	PROPN
biomedich-1001	1	95	.	.	PUNCT
biomedich-1001	2	1	peta	peta	PROPN
biomedich-1001	2	2	no.177	no.177	PROPN
biomedich-1001	2	3	tasikmalaya	tasikmalaya	PROPN
biomedich-1001	2	4	,	,	PUNCT
biomedich-1001	2	5	telp	telp	NOUN
biomedich-1001	2	6	.	.	PUNCT
biomedich-1001	3	1	(	(	PUNCT
biomedich-1001	3	2	0265	0265	NUM
biomedich-1001	3	3	)	)	PUNCT
biomedich-1001	3	4	326058	326058	NUM
biomedich-1001	3	5	indonesia	indonesia	PROPN
biomedich-1001	3	6	.	.	PUNCT
biomedich-1001	4	1	corresponding	correspond	VERB
biomedich-1001	4	2	author	author	NOUN
biomedich-1001	4	3	*	*	PUNCT
biomedich-1001	4	4	alinofriyaldi13@gmail.com	alinofriyaldi13@gmail.com	X
biomedich-1001	4	5	abstract	abstract	ADJ
biomedich-1001	4	6	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	4	7	is	be	AUX
biomedich-1001	4	8	a	a	DET
biomedich-1001	4	9	disorder	disorder	NOUN
biomedich-1001	4	10	marked	mark	VERB
biomedich-1001	4	11	by	by	ADP
biomedich-1001	4	12	elevated	elevated	ADJ
biomedich-1001	4	13	concentrations	concentration	NOUN
biomedich-1001	4	14	of	of	ADP
biomedich-1001	4	15	uric	uric	ADJ
biomedich-1001	4	16	acid	acid	NOUN
biomedich-1001	4	17	in	in	ADP
biomedich-1001	4	18	the	the	DET
biomedich-1001	4	19	bloodstream	bloodstream	NOUN
biomedich-1001	4	20	,	,	PUNCT
biomedich-1001	4	21	which	which	PRON
biomedich-1001	4	22	can	can	AUX
biomedich-1001	4	23	trigger	trigger	VERB
biomedich-1001	4	24	gout	gout	NOUN
biomedich-1001	4	25	and	and	CCONJ
biomedich-1001	4	26	other	other	ADJ
biomedich-1001	4	27	metabolic	metabolic	NOUN
biomedich-1001	4	28	complications	complication	NOUN
biomedich-1001	4	29	.	.	PUNCT
biomedich-1001	5	1	conventional	conventional	ADJ
biomedich-1001	5	2	therapies	therapy	NOUN
biomedich-1001	5	3	such	such	ADJ
biomedich-1001	5	4	as	as	ADP
biomedich-1001	5	5	allopurinol	allopurinol	NOUN
biomedich-1001	5	6	are	be	AUX
biomedich-1001	5	7	effective	effective	ADJ
biomedich-1001	5	8	but	but	CCONJ
biomedich-1001	5	9	often	often	ADV
biomedich-1001	5	10	cause	cause	VERB
biomedich-1001	5	11	side	side	NOUN
biomedich-1001	5	12	effects	effect	NOUN
biomedich-1001	5	13	.	.	PUNCT
biomedich-1001	6	1	this	this	DET
biomedich-1001	6	2	study	study	NOUN
biomedich-1001	6	3	aims	aim	VERB
biomedich-1001	6	4	to	to	PART
biomedich-1001	6	5	explore	explore	VERB
biomedich-1001	6	6	the	the	DET
biomedich-1001	6	7	potential	potential	NOUN
biomedich-1001	6	8	of	of	ADP
biomedich-1001	6	9	bioactive	bioactive	ADJ
biomedich-1001	6	10	compounds	compound	NOUN
biomedich-1001	6	11	from	from	ADP
biomedich-1001	6	12	cardamom	cardamom	NOUN
biomedich-1001	6	13	leaves	leave	NOUN
biomedich-1001	6	14	(	(	PUNCT
biomedich-1001	6	15	wurfbania	wurfbania	PROPN
biomedich-1001	6	16	compacta	compacta	NOUN
biomedich-1001	6	17	)	)	PUNCT
biomedich-1001	6	18	as	as	ADP
biomedich-1001	6	19	antihyperuricemic	antihyperuricemic	ADJ
biomedich-1001	6	20	agents	agent	NOUN
biomedich-1001	6	21	through	through	ADP
biomedich-1001	6	22	an	an	DET
biomedich-1001	6	23	in	in	ADP
biomedich-1001	6	24	silico	silico	NOUN
biomedich-1001	6	25	approach	approach	NOUN
biomedich-1001	6	26	.	.	PUNCT
biomedich-1001	7	1	the	the	DET
biomedich-1001	7	2	methods	method	NOUN
biomedich-1001	7	3	used	use	VERB
biomedich-1001	7	4	include	include	VERB
biomedich-1001	7	5	mining	mine	VERB
biomedich-1001	7	6	phytochemical	phytochemical	ADJ
biomedich-1001	7	7	data	datum	NOUN
biomedich-1001	7	8	from	from	ADP
biomedich-1001	7	9	the	the	DET
biomedich-1001	7	10	literature	literature	NOUN
biomedich-1001	7	11	,	,	PUNCT
biomedich-1001	7	12	predicting	predict	VERB
biomedich-1001	7	13	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	7	14	properties	property	NOUN
biomedich-1001	7	15	and	and	CCONJ
biomedich-1001	7	16	toxicity	toxicity	NOUN
biomedich-1001	7	17	(	(	PUNCT
biomedich-1001	7	18	admet	admet	PROPN
biomedich-1001	7	19	)	)	PUNCT
biomedich-1001	7	20	,	,	PUNCT
biomedich-1001	7	21	molecular	molecular	ADJ
biomedich-1001	7	22	docking	docking	NOUN
biomedich-1001	7	23	as	as	ADV
biomedich-1001	7	24	well	well	ADV
biomedich-1001	7	25	as	as	ADP
biomedich-1001	7	26	molecular	molecular	ADJ
biomedich-1001	7	27	dynamic	dynamic	ADJ
biomedich-1001	7	28	.	.	PUNCT
biomedich-1001	8	1	the	the	DET
biomedich-1001	8	2	screening	screening	NOUN
biomedich-1001	8	3	results	result	NOUN
biomedich-1001	8	4	show	show	VERB
biomedich-1001	8	5	that	that	SCONJ
biomedich-1001	8	6	the	the	DET
biomedich-1001	8	7	compound	compound	NOUN
biomedich-1001	8	8	with	with	ADP
biomedich-1001	8	9	the	the	DET
biomedich-1001	8	10	most	most	ADV
biomedich-1001	8	11	stable	stable	ADJ
biomedich-1001	8	12	interaction	interaction	NOUN
biomedich-1001	8	13	from	from	ADP
biomedich-1001	8	14	cardamom	cardamom	PROPN
biomedich-1001	8	15	(	(	PUNCT
biomedich-1001	8	16	wurfbania	wurfbania	PROPN
biomedich-1001	8	17	compacta	compacta	NOUN
biomedich-1001	8	18	)	)	PUNCT
biomedich-1001	8	19	with	with	ADP
biomedich-1001	8	20	receptors	receptor	NOUN
biomedich-1001	8	21	that	that	PRON
biomedich-1001	8	22	play	play	VERB
biomedich-1001	8	23	a	a	DET
biomedich-1001	8	24	role	role	NOUN
biomedich-1001	8	25	in	in	ADP
biomedich-1001	8	26	inhibiting	inhibit	VERB
biomedich-1001	8	27	xanthine	xanthine	NOUN
biomedich-1001	8	28	oxidase	oxidase	NOUN
biomedich-1001	8	29	enzyme	enzyme	NOUN
biomedich-1001	8	30	in	in	ADP
biomedich-1001	8	31	silico	silico	NOUN
biomedich-1001	8	32	is	be	AUX
biomedich-1001	8	33	the	the	DET
biomedich-1001	8	34	compound	compound	NOUN
biomedich-1001	8	35	kaempferol	kaempferol	NOUN
biomedich-1001	8	36	with	with	ADP
biomedich-1001	8	37	a	a	DET
biomedich-1001	8	38	binding	bind	VERB
biomedich-1001	8	39	energy	energy	NOUN
biomedich-1001	8	40	value	value	NOUN
biomedich-1001	8	41	of	of	ADP
biomedich-1001	8	42	-8.1	-8.1	PROPN
biomedich-1001	8	43	kcal	kcal	PROPN
biomedich-1001	8	44	/	/	SYM
biomedich-1001	8	45	mol	mol	PROPN
biomedich-1001	8	46	and	and	CCONJ
biomedich-1001	8	47	ki	ki	PROPN
biomedich-1001	8	48	1.15	1.15	NUM
biomedich-1001	8	49	um	um	INTJ
biomedich-1001	8	50	(	(	PUNCT
biomedich-1001	8	51	micromolar	micromolar	NOUN
biomedich-1001	8	52	)	)	PUNCT
biomedich-1001	8	53	.	.	PUNCT
biomedich-1001	9	1	admet	admet	PROPN
biomedich-1001	9	2	analysis	analysis	NOUN
biomedich-1001	9	3	indicates	indicate	VERB
biomedich-1001	9	4	that	that	SCONJ
biomedich-1001	9	5	the	the	DET
biomedich-1001	9	6	main	main	ADJ
biomedich-1001	9	7	candidate	candidate	NOUN
biomedich-1001	9	8	has	have	VERB
biomedich-1001	9	9	a	a	DET
biomedich-1001	9	10	good	good	ADJ
biomedich-1001	9	11	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	9	12	profile	profile	NOUN
biomedich-1001	9	13	and	and	CCONJ
biomedich-1001	9	14	low	low	ADJ
biomedich-1001	9	15	toxicity	toxicity	NOUN
biomedich-1001	9	16	potential	potential	NOUN
biomedich-1001	9	17	.	.	PUNCT
biomedich-1001	10	1	based	base	VERB
biomedich-1001	10	2	on	on	ADP
biomedich-1001	10	3	the	the	DET
biomedich-1001	10	4	results	result	NOUN
biomedich-1001	10	5	of	of	ADP
biomedich-1001	10	6	the	the	DET
biomedich-1001	10	7	rmsd	rmsd	NOUN
biomedich-1001	10	8	and	and	CCONJ
biomedich-1001	10	9	rmsf	rmsf	VERB
biomedich-1001	10	10	molecular	molecular	ADJ
biomedich-1001	10	11	dynamic	dynamic	ADJ
biomedich-1001	10	12	analysis	analysis	NOUN
biomedich-1001	10	13	,	,	PUNCT
biomedich-1001	10	14	the	the	DET
biomedich-1001	10	15	kaempferol	kaempferol	NOUN
biomedich-1001	10	16	compound	compound	NOUN
biomedich-1001	10	17	shows	show	VERB
biomedich-1001	10	18	a	a	DET
biomedich-1001	10	19	stable	stable	ADJ
biomedich-1001	10	20	level	level	NOUN
biomedich-1001	10	21	of	of	ADP
biomedich-1001	10	22	interaction	interaction	NOUN
biomedich-1001	10	23	and	and	CCONJ
biomedich-1001	10	24	has	have	VERB
biomedich-1001	10	25	3	3	NUM
biomedich-1001	10	26	amino	amino	NOUN
biomedich-1001	10	27	acid	acid	NOUN
biomedich-1001	10	28	similarities	similarity	NOUN
biomedich-1001	10	29	with	with	ADP
biomedich-1001	10	30	the	the	DET
biomedich-1001	10	31	comparison	comparison	NOUN
biomedich-1001	10	32	drug	drug	NOUN
biomedich-1001	10	33	allopurinol	allopurinol	NOUN
biomedich-1001	10	34	,	,	PUNCT
biomedich-1001	10	35	namely	namely	ADV
biomedich-1001	10	36	thr1010	thr1010	NOUN
biomedich-1001	10	37	,	,	PUNCT
biomedich-1001	10	38	val1011	val1011	NOUN
biomedich-1001	10	39	and	and	CCONJ
biomedich-1001	10	40	ala1078	ala1078	VERB
biomedich-1001	10	41	,	,	PUNCT
biomedich-1001	10	42	so	so	SCONJ
biomedich-1001	10	43	it	it	PRON
biomedich-1001	10	44	has	have	VERB
biomedich-1001	10	45	the	the	DET
biomedich-1001	10	46	potential	potential	NOUN
biomedich-1001	10	47	to	to	PART
biomedich-1001	10	48	be	be	AUX
biomedich-1001	10	49	used	use	VERB
biomedich-1001	10	50	as	as	ADP
biomedich-1001	10	51	a	a	DET
biomedich-1001	10	52	candidate	candidate	NOUN
biomedich-1001	10	53	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	10	54	drug	drug	NOUN
biomedich-1001	10	55	.	.	PUNCT
biomedich-1001	11	1	these	these	DET
biomedich-1001	11	2	findings	finding	NOUN
biomedich-1001	11	3	suggest	suggest	VERB
biomedich-1001	11	4	that	that	SCONJ
biomedich-1001	11	5	cardamom	cardamom	NOUN
biomedich-1001	11	6	leaves	leave	NOUN
biomedich-1001	11	7	have	have	VERB
biomedich-1001	11	8	prospects	prospect	NOUN
biomedich-1001	11	9	as	as	ADP
biomedich-1001	11	10	a	a	DET
biomedich-1001	11	11	source	source	NOUN
biomedich-1001	11	12	of	of	ADP
biomedich-1001	11	13	natural	natural	ADJ
biomedich-1001	11	14	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	11	15	compounds	compound	NOUN
biomedich-1001	11	16	.	.	PUNCT
biomedich-1001	12	1	further	far	ADV
biomedich-1001	12	2	in	in	ADP
biomedich-1001	12	3	vitro	vitro	X
biomedich-1001	12	4	and	and	CCONJ
biomedich-1001	12	5	in	in	ADP
biomedich-1001	12	6	vivo	vivo	ADJ
biomedich-1001	12	7	studies	study	NOUN
biomedich-1001	12	8	are	be	AUX
biomedich-1001	12	9	needed	need	VERB
biomedich-1001	12	10	to	to	PART
biomedich-1001	12	11	verify	verify	VERB
biomedich-1001	12	12	the	the	DET
biomedich-1001	12	13	biological	biological	ADJ
biomedich-1001	12	14	activity	activity	NOUN
biomedich-1001	12	15	and	and	CCONJ
biomedich-1001	12	16	safety	safety	NOUN
biomedich-1001	12	17	of	of	ADP
biomedich-1001	12	18	its	its	PRON
biomedich-1001	12	19	use	use	NOUN
biomedich-1001	12	20	.	.	PUNCT
biomedich-1001	13	1	keywords	keyword	NOUN
biomedich-1001	13	2	:	:	PUNCT
biomedich-1001	13	3	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	13	4	;	;	PUNCT
biomedich-1001	13	5	java	java	PROPN
biomedich-1001	13	6	cardamom	cardamom	PROPN
biomedich-1001	13	7	leaves	leave	VERB
biomedich-1001	13	8	;	;	PUNCT
biomedich-1001	13	9	in	in	ADP
biomedich-1001	13	10	silico	silico	NOUN
biomedich-1001	13	11	;	;	PUNCT
biomedich-1001	13	12	molecular	molecular	ADJ
biomedich-1001	13	13	dynamic	dynamic	ADJ
biomedich-1001	13	14	;	;	PUNCT
biomedich-1001	13	15	xanthine	xanthine	NOUN
biomedich-1001	13	16	oxidase	oxidase	NOUN
biomedich-1001	13	17	.	.	PUNCT
biomedich-1001	14	1	introduction	introduction	NOUN
biomedich-1001	14	2	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	14	3	is	be	AUX
biomedich-1001	14	4	a	a	DET
biomedich-1001	14	5	health	health	NOUN
biomedich-1001	14	6	condition	condition	NOUN
biomedich-1001	14	7	characterized	characterize	VERB
biomedich-1001	14	8	by	by	ADP
biomedich-1001	14	9	elevated	elevated	ADJ
biomedich-1001	14	10	levels	level	NOUN
biomedich-1001	14	11	of	of	ADP
biomedich-1001	14	12	uric	uric	ADJ
biomedich-1001	14	13	acid	acid	NOUN
biomedich-1001	14	14	in	in	ADP
biomedich-1001	14	15	the	the	DET
biomedich-1001	14	16	blood	blood	NOUN
biomedich-1001	14	17	.	.	PUNCT
biomedich-1001	15	1	this	this	DET
biomedich-1001	15	2	condition	condition	NOUN
biomedich-1001	15	3	often	often	ADV
biomedich-1001	15	4	does	do	AUX
biomedich-1001	15	5	not	not	PART
biomedich-1001	15	6	show	show	VERB
biomedich-1001	15	7	any	any	DET
biomedich-1001	15	8	signs	sign	NOUN
biomedich-1001	15	9	or	or	CCONJ
biomedich-1001	15	10	symptoms	symptom	NOUN
biomedich-1001	15	11	during	during	ADP
biomedich-1001	15	12	its	its	PRON
biomedich-1001	15	13	early	early	ADJ
biomedich-1001	15	14	stages	stage	NOUN
biomedich-1001	15	15	.	.	PUNCT
biomedich-1001	16	1	typically	typically	ADV
biomedich-1001	16	2	,	,	PUNCT
biomedich-1001	16	3	uric	uric	ADJ
biomedich-1001	16	4	acid	acid	NOUN
biomedich-1001	16	5	levels	level	NOUN
biomedich-1001	16	6	are	be	AUX
biomedich-1001	16	7	considered	consider	VERB
biomedich-1001	16	8	high	high	ADJ
biomedich-1001	16	9	when	when	SCONJ
biomedich-1001	16	10	they	they	PRON
biomedich-1001	16	11	exceed	exceed	VERB
biomedich-1001	16	12	7.0	7.0	NUM
biomedich-1001	16	13	mg	mg	PROPN
biomedich-1001	16	14	/	/	SYM
biomedich-1001	16	15	dl	dl	PROPN
biomedich-1001	16	16	in	in	ADP
biomedich-1001	16	17	men	man	NOUN
biomedich-1001	16	18	or	or	CCONJ
biomedich-1001	16	19	6.0	6.0	NUM
biomedich-1001	16	20	mg	mg	NUM
biomedich-1001	16	21	/	/	SYM
biomedich-1001	16	22	dl	dl	PROPN
biomedich-1001	16	23	in	in	ADP
biomedich-1001	16	24	women	woman	NOUN
biomedich-1001	16	25	(	(	PUNCT
biomedich-1001	16	26	sovia	sovia	PROPN
biomedich-1001	16	27	et	et	PROPN
biomedich-1001	16	28	al	al	PROPN
biomedich-1001	16	29	.	.	PROPN
biomedich-1001	16	30	,	,	PUNCT
biomedich-1001	16	31	2025	2025	NUM
biomedich-1001	16	32	)	)	PUNCT
biomedich-1001	16	33	.	.	PUNCT
biomedich-1001	17	1	hyperuricemia	hyperuricemia	INTJ
biomedich-1001	17	2	,	,	PUNCT
biomedich-1001	17	3	which	which	PRON
biomedich-1001	17	4	means	mean	VERB
biomedich-1001	17	5	having	have	VERB
biomedich-1001	17	6	high	high	ADJ
biomedich-1001	17	7	levels	level	NOUN
biomedich-1001	17	8	of	of	ADP
biomedich-1001	17	9	uric	uric	ADJ
biomedich-1001	17	10	acid	acid	NOUN
biomedich-1001	17	11	in	in	ADP
biomedich-1001	17	12	the	the	DET
biomedich-1001	17	13	blood	blood	NOUN
biomedich-1001	17	14	,	,	PUNCT
biomedich-1001	17	15	is	be	AUX
biomedich-1001	17	16	connected	connect	VERB
biomedich-1001	17	17	to	to	ADP
biomedich-1001	17	18	several	several	ADJ
biomedich-1001	17	19	health	health	NOUN
biomedich-1001	17	20	issues	issue	NOUN
biomedich-1001	17	21	like	like	ADP
biomedich-1001	17	22	gout	gout	NOUN
biomedich-1001	17	23	,	,	PUNCT
biomedich-1001	17	24	heart	heart	NOUN
biomedich-1001	17	25	problems	problem	NOUN
biomedich-1001	17	26	,	,	PUNCT
biomedich-1001	17	27	kidney	kidney	NOUN
biomedich-1001	17	28	diseases	disease	NOUN
biomedich-1001	17	29	,	,	PUNCT
biomedich-1001	17	30	metabolic	metabolic	NOUN
biomedich-1001	17	31	syndrome	syndrome	NOUN
biomedich-1001	17	32	,	,	PUNCT
biomedich-1001	17	33	and	and	CCONJ
biomedich-1001	17	34	diabetes	diabetes	NOUN
biomedich-1001	17	35	(	(	PUNCT
biomedich-1001	17	36	du	du	PROPN
biomedich-1001	17	37	et	et	PROPN
biomedich-1001	17	38	al	al	PROPN
biomedich-1001	17	39	.	.	PROPN
biomedich-1001	17	40	,	,	PUNCT
biomedich-1001	17	41	2024	2024	NUM
biomedich-1001	17	42	)	)	PUNCT
biomedich-1001	17	43	.	.	PUNCT
biomedich-1001	18	1	a	a	DET
biomedich-1001	18	2	crucial	crucial	ADJ
biomedich-1001	18	3	enzyme	enzyme	NOUN
biomedich-1001	18	4	involved	involve	VERB
biomedich-1001	18	5	in	in	ADP
biomedich-1001	18	6	producing	produce	VERB
biomedich-1001	18	7	uric	uric	ADJ
biomedich-1001	18	8	acid	acid	NOUN
biomedich-1001	18	9	is	be	AUX
biomedich-1001	18	10	called	call	VERB
biomedich-1001	18	11	xanthine	xanthine	NOUN
biomedich-1001	18	12	oxidase	oxidase	NOUN
biomedich-1001	18	13	(	(	PUNCT
biomedich-1001	18	14	xo	xo	PROPN
biomedich-1001	18	15	)	)	PUNCT
biomedich-1001	18	16	.	.	PUNCT
biomedich-1001	19	1	this	this	DET
biomedich-1001	19	2	enzyme	enzyme	NOUN
biomedich-1001	19	3	helps	help	VERB
biomedich-1001	19	4	convert	convert	VERB
biomedich-1001	19	5	hypoxanthine	hypoxanthine	NOUN
biomedich-1001	19	6	into	into	ADP
biomedich-1001	19	7	xanthine	xanthine	NOUN
biomedich-1001	19	8	,	,	PUNCT
biomedich-1001	19	9	and	and	CCONJ
biomedich-1001	19	10	then	then	ADV
biomedich-1001	19	11	into	into	ADP
biomedich-1001	19	12	uric	uric	ADJ
biomedich-1001	19	13	acid	acid	NOUN
biomedich-1001	19	14	.	.	PUNCT
biomedich-1001	20	1	blocking	block	VERB
biomedich-1001	20	2	xo	xo	PROPN
biomedich-1001	20	3	is	be	AUX
biomedich-1001	20	4	a	a	DET
biomedich-1001	20	5	proven	prove	VERB
biomedich-1001	20	6	method	method	NOUN
biomedich-1001	20	7	used	use	VERB
biomedich-1001	20	8	to	to	PART
biomedich-1001	20	9	treat	treat	VERB
biomedich-1001	20	10	high	high	ADJ
biomedich-1001	20	11	levels	level	NOUN
biomedich-1001	20	12	of	of	ADP
biomedich-1001	20	13	uric	uric	ADJ
biomedich-1001	20	14	acid	acid	NOUN
biomedich-1001	20	15	in	in	ADP
biomedich-1001	20	16	the	the	DET
biomedich-1001	20	17	blood	blood	NOUN
biomedich-1001	20	18	(	(	PUNCT
biomedich-1001	20	19	liu	liu	PROPN
biomedich-1001	20	20	et	et	PROPN
biomedich-1001	20	21	al	al	PROPN
biomedich-1001	20	22	.	.	PROPN
biomedich-1001	20	23	,	,	PUNCT
biomedich-1001	20	24	2021	2021	NUM
biomedich-1001	20	25	)	)	PUNCT
biomedich-1001	20	26	.	.	PUNCT
biomedich-1001	21	1	while	while	SCONJ
biomedich-1001	21	2	traditional	traditional	ADJ
biomedich-1001	21	3	xo	xo	PROPN
biomedich-1001	21	4	inhibitors	inhibitor	NOUN
biomedich-1001	21	5	like	like	ADP
biomedich-1001	21	6	allopurinol	allopurinol	NOUN
biomedich-1001	21	7	and	and	CCONJ
biomedich-1001	21	8	febuxostat	febuxostat	NOUN
biomedich-1001	21	9	work	work	NOUN
biomedich-1001	21	10	well	well	ADV
biomedich-1001	21	11	,	,	PUNCT
biomedich-1001	21	12	they	they	PRON
biomedich-1001	21	13	often	often	ADV
biomedich-1001	21	14	cause	cause	VERB
biomedich-1001	21	15	unwanted	unwanted	ADJ
biomedich-1001	21	16	side	side	NOUN
biomedich-1001	21	17	effects	effect	NOUN
biomedich-1001	21	18	,	,	PUNCT
biomedich-1001	21	19	leading	lead	VERB
biomedich-1001	21	20	to	to	ADP
biomedich-1001	21	21	increased	increase	VERB
biomedich-1001	21	22	exploration	exploration	NOUN
biomedich-1001	21	23	of	of	ADP
biomedich-1001	21	24	natural	natural	ADJ
biomedich-1001	21	25	products	product	NOUN
biomedich-1001	21	26	as	as	ADP
biomedich-1001	21	27	potentially	potentially	ADV
biomedich-1001	21	28	safer	safe	ADJ
biomedich-1001	21	29	options	option	NOUN
biomedich-1001	21	30	(	(	PUNCT
biomedich-1001	21	31	mehmood	mehmood	PROPN
biomedich-1001	21	32	et	et	PROPN
biomedich-1001	21	33	al	al	PROPN
biomedich-1001	21	34	.	.	PROPN
biomedich-1001	21	35	,	,	PUNCT
biomedich-1001	21	36	2019	2019	NUM
biomedich-1001	21	37	)	)	PUNCT
biomedich-1001	21	38	.	.	PUNCT
biomedich-1001	22	1	recent	recent	ADJ
biomedich-1001	22	2	research	research	NOUN
biomedich-1001	22	3	has	have	AUX
biomedich-1001	22	4	shown	show	VERB
biomedich-1001	22	5	that	that	SCONJ
biomedich-1001	22	6	bioactive	bioactive	VERB
biomedich-1001	22	7	compounds	compound	NOUN
biomedich-1001	22	8	from	from	ADP
biomedich-1001	22	9	plants	plant	NOUN
biomedich-1001	22	10	,	,	PUNCT
biomedich-1001	22	11	such	such	ADJ
biomedich-1001	22	12	as	as	ADP
biomedich-1001	22	13	flavonoids	flavonoid	NOUN
biomedich-1001	22	14	,	,	PUNCT
biomedich-1001	22	15	polyphenols	polyphenol	NOUN
biomedich-1001	22	16	,	,	PUNCT
biomedich-1001	22	17	and	and	CCONJ
biomedich-1001	22	18	peptides	peptide	NOUN
biomedich-1001	22	19	,	,	PUNCT
biomedich-1001	22	20	have	have	VERB
biomedich-1001	22	21	the	the	DET
biomedich-1001	22	22	ability	ability	NOUN
biomedich-1001	22	23	to	to	PART
biomedich-1001	22	24	inhibit	inhibit	VERB
biomedich-1001	22	25	xanthine	xanthine	NOUN
biomedich-1001	22	26	oxidase	oxidase	NOUN
biomedich-1001	22	27	and	and	CCONJ
biomedich-1001	22	28	reduce	reduce	VERB
biomedich-1001	22	29	high	high	ADJ
biomedich-1001	22	30	uric	uric	ADJ
biomedich-1001	22	31	acid	acid	NOUN
biomedich-1001	22	32	levels	level	NOUN
biomedich-1001	22	33	.	.	PUNCT
biomedich-1001	23	1	these	these	DET
biomedich-1001	23	2	findings	finding	NOUN
biomedich-1001	23	3	are	be	AUX
biomedich-1001	23	4	backed	back	VERB
biomedich-1001	23	5	by	by	ADP
biomedich-1001	23	6	both	both	PRON
biomedich-1001	23	7	in	in	ADP
biomedich-1001	23	8	vitro	vitro	X
biomedich-1001	23	9	assays	assay	NOUN
biomedich-1001	23	10	and	and	CCONJ
biomedich-1001	23	11	in	in	ADP
biomedich-1001	23	12	silico	silico	NOUN
biomedich-1001	23	13	molecular	molecular	ADJ
biomedich-1001	23	14	modeling	modeling	NOUN
biomedich-1001	23	15	techniques	technique	NOUN
biomedich-1001	23	16	(	(	PUNCT
biomedich-1001	23	17	dirgantara	dirgantara	NOUN
biomedich-1001	23	18	et	et	PROPN
biomedich-1001	23	19	al	al	PROPN
biomedich-1001	23	20	.	.	PROPN
biomedich-1001	23	21	,	,	PUNCT
biomedich-1001	23	22	2022	2022	NUM
biomedich-1001	23	23	)	)	PUNCT
biomedich-1001	23	24	.	.	PUNCT
biomedich-1001	24	1	one	one	NUM
biomedich-1001	24	2	of	of	ADP
biomedich-1001	24	3	the	the	DET
biomedich-1001	24	4	plants	plant	NOUN
biomedich-1001	24	5	that	that	PRON
biomedich-1001	24	6	contains	contain	VERB
biomedich-1001	24	7	flavonoids	flavonoid	NOUN
biomedich-1001	24	8	is	be	AUX
biomedich-1001	24	9	cardamom	cardamom	NOUN
biomedich-1001	24	10	.	.	PUNCT
biomedich-1001	25	1	there	there	PRON
biomedich-1001	25	2	are	be	VERB
biomedich-1001	25	3	several	several	ADJ
biomedich-1001	25	4	types	type	NOUN
biomedich-1001	25	5	of	of	ADP
biomedich-1001	25	6	cardamom	cardamom	NOUN
biomedich-1001	25	7	,	,	PUNCT
biomedich-1001	25	8	one	one	NUM
biomedich-1001	25	9	of	of	ADP
biomedich-1001	25	10	which	which	PRON
biomedich-1001	25	11	is	be	AUX
biomedich-1001	25	12	javanese	javanese	PROPN
biomedich-1001	25	13	cardamom	cardamom	PROPN
biomedich-1001	25	14	(	(	PUNCT
biomedich-1001	25	15	wurfbainia	wurfbainia	PROPN
biomedich-1001	25	16	compacta	compacta	PROPN
biomedich-1001	25	17	)	)	PUNCT
biomedich-1001	25	18	,	,	PUNCT
biomedich-1001	25	19	,	,	PUNCT
biomedich-1001	25	20	whose	whose	DET
biomedich-1001	25	21	boiled	boil	VERB
biomedich-1001	25	22	fruit	fruit	NOUN
biomedich-1001	25	23	extract	extract	NOUN
biomedich-1001	25	24	is	be	AUX
biomedich-1001	25	25	empirically	empirically	ADV
biomedich-1001	25	26	believed	believe	VERB
biomedich-1001	25	27	to	to	PART
biomedich-1001	25	28	be	be	AUX
biomedich-1001	25	29	used	use	VERB
biomedich-1001	25	30	as	as	ADP
biomedich-1001	25	31	an	an	DET
biomedich-1001	25	32	antihyperuricemic	antihyperuricemic	ADJ
biomedich-1001	25	33	agent	agent	NOUN
biomedich-1001	25	34	.	.	PUNCT
biomedich-1001	26	1	the	the	DET
biomedich-1001	26	2	flavonoid	flavonoid	PROPN
biomedich-1001	26	3	derivative	derivative	PROPN
biomedich-1001	26	4	from	from	ADP
biomedich-1001	26	5	javanese	javanese	PROPN
biomedich-1001	26	6	cardamom	cardamom	PROPN
biomedich-1001	26	7	fruit	fruit	PROPN
biomedich-1001	26	8	,	,	PUNCT
biomedich-1001	26	9	in	in	ADP
biomedich-1001	26	10	silico	silico	NOUN
biomedich-1001	26	11	,	,	PUNCT
biomedich-1001	26	12	is	be	AUX
biomedich-1001	26	13	a	a	DET
biomedich-1001	26	14	candidate	candidate	NOUN
biomedich-1001	26	15	that	that	PRON
biomedich-1001	26	16	plays	play	VERB
biomedich-1001	26	17	a	a	DET
biomedich-1001	26	18	role	role	NOUN
biomedich-1001	26	19	as	as	ADP
biomedich-1001	26	20	an	an	DET
biomedich-1001	26	21	antihyperuricemic	antihyperuricemic	ADJ
biomedich-1001	26	22	,	,	PUNCT
biomedich-1001	26	23	namely	namely	ADV
biomedich-1001	26	24	the	the	DET
biomedich-1001	26	25	compound	compound	NOUN
biomedich-1001	26	26	3	3	NUM
biomedich-1001	26	27	-	-	PUNCT
biomedich-1001	26	28	cyclohexene-1	cyclohexene-1	NOUN
biomedich-1001	26	29	-	-	PUNCT
biomedich-1001	26	30	methanol	methanol	NOUN
biomedich-1001	26	31	(	(	PUNCT
biomedich-1001	26	32	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	26	33	et	et	PROPN
biomedich-1001	26	34	al	al	PROPN
biomedich-1001	26	35	.	.	PROPN
biomedich-1001	26	36	,	,	PUNCT
biomedich-1001	26	37	2025	2025	NUM
biomedich-1001	26	38	)	)	PUNCT
biomedich-1001	26	39	.	.	PUNCT
biomedich-1001	27	1	in	in	ADP
biomedich-1001	27	2	the	the	DET
biomedich-1001	27	3	realm	realm	NOUN
biomedich-1001	27	4	of	of	ADP
biomedich-1001	27	5	medicinal	medicinal	ADJ
biomedich-1001	27	6	plants	plant	NOUN
biomedich-1001	27	7	,	,	PUNCT
biomedich-1001	27	8	cardamom	cardamom	NOUN
biomedich-1001	27	9	,	,	PUNCT
biomedich-1001	27	10	has	have	AUX
biomedich-1001	27	11	been	be	AUX
biomedich-1001	27	12	used	use	VERB
biomedich-1001	27	13	for	for	ADP
biomedich-1001	27	14	centuries	century	NOUN
biomedich-1001	27	15	in	in	ADP
biomedich-1001	27	16	different	different	ADJ
biomedich-1001	27	17	cultures	culture	NOUN
biomedich-1001	27	18	for	for	ADP
biomedich-1001	27	19	its	its	PRON
biomedich-1001	27	20	healing	healing	NOUN
biomedich-1001	27	21	benefits	benefit	NOUN
biomedich-1001	27	22	.	.	PUNCT
biomedich-1001	28	1	cardamom	cardamom	NOUN
biomedich-1001	28	2	leaf	leaf	NOUN
biomedich-1001	28	3	extract	extract	NOUN
biomedich-1001	28	4	was	be	AUX
biomedich-1001	28	5	found	find	VERB
biomedich-1001	28	6	to	to	PART
biomedich-1001	28	7	have	have	VERB
biomedich-1001	28	8	strong	strong	ADJ
biomedich-1001	28	9	antifungal	antifungal	ADJ
biomedich-1001	28	10	activity	activity	NOUN
biomedich-1001	28	11	against	against	ADP
biomedich-1001	28	12	different	different	ADJ
biomedich-1001	28	13	fungal	fungal	ADJ
biomedich-1001	28	14	plant	plant	NOUN
biomedich-1001	28	15	pathogens	pathogen	NOUN
biomedich-1001	28	16	and	and	CCONJ
biomedich-1001	28	17	also	also	ADV
biomedich-1001	28	18	exhibited	exhibit	VERB
biomedich-1001	28	19	antimicrobial	antimicrobial	ADJ
biomedich-1001	28	20	effects	effect	NOUN
biomedich-1001	28	21	against	against	ADP
biomedich-1001	28	22	both	both	DET
biomedich-1001	28	23	types	type	NOUN
biomedich-1001	28	24	of	of	ADP
biomedich-1001	28	25	bacteria	bacteria	NOUN
biomedich-1001	28	26	,	,	PUNCT
biomedich-1001	28	27	which	which	PRON
biomedich-1001	28	28	are	be	AUX
biomedich-1001	28	29	gram	gram	NOUN
biomedich-1001	28	30	-	-	PUNCT
biomedich-1001	28	31	positive	positive	ADJ
biomedich-1001	28	32	and	and	CCONJ
biomedich-1001	28	33	gram	gram	NOUN
biomedich-1001	28	34	-	-	PUNCT
biomedich-1001	28	35	negative	negative	NOUN
biomedich-1001	28	36	that	that	PRON
biomedich-1001	28	37	cause	cause	VERB
biomedich-1001	28	38	human	human	ADJ
biomedich-1001	28	39	infections	infection	NOUN
biomedich-1001	28	40	,	,	PUNCT
biomedich-1001	28	41	and	and	CCONJ
biomedich-1001	28	42	exhibited	exhibit	VERB
biomedich-1001	28	43	antihyperglycemic	antihyperglycemic	ADJ
biomedich-1001	28	44	effects	effect	NOUN
biomedich-1001	28	45	by	by	ADP
biomedich-1001	28	46	reducing	reduce	VERB
biomedich-1001	28	47	glucose	glucose	NOUN
biomedich-1001	28	48	absorption	absorption	NOUN
biomedich-1001	28	49	and	and	CCONJ
biomedich-1001	28	50	mimicking	mimic	VERB
biomedich-1001	28	51	the	the	DET
biomedich-1001	28	52	action	action	NOUN
biomedich-1001	28	53	of	of	ADP
biomedich-1001	28	54	insulin	insulin	NOUN
biomedich-1001	28	55	(	(	PUNCT
biomedich-1001	28	56	mekky	mekky	VERB
biomedich-1001	28	57	et	et	PROPN
biomedich-1001	28	58	al	al	PROPN
biomedich-1001	28	59	.	.	PROPN
biomedich-1001	28	60	,	,	PUNCT
biomedich-1001	28	61	2023	2023	NUM
biomedich-1001	28	62	)	)	PUNCT
biomedich-1001	28	63	.	.	PUNCT
biomedich-1001	29	1	the	the	DET
biomedich-1001	29	2	bioactive	bioactive	ADJ
biomedich-1001	29	3	properties	property	NOUN
biomedich-1001	29	4	of	of	ADP
biomedich-1001	29	5	cardamom	cardamom	NOUN
biomedich-1001	29	6	leaves	leave	NOUN
biomedich-1001	29	7	have	have	AUX
biomedich-1001	29	8	not	not	PART
biomedich-1001	29	9	been	be	AUX
biomedich-1001	29	10	thoroughly	thoroughly	ADV
biomedich-1001	29	11	studied	study	VERB
biomedich-1001	29	12	,	,	PUNCT
biomedich-1001	29	13	especially	especially	ADV
biomedich-1001	29	14	manuscript	manuscript	NOUN
biomedich-1001	29	15	received	receive	VERB
biomedich-1001	29	16	:	:	PUNCT
biomedich-1001	29	17	25	25	NUM
biomedich-1001	29	18	september	september	PROPN
biomedich-1001	29	19	,	,	PUNCT
biomedich-1001	29	20	2025	2025	NUM
biomedich-1001	29	21	.	.	PUNCT
biomedich-1001	30	1	revision	revision	NOUN
biomedich-1001	30	2	accepted	accept	VERB
biomedich-1001	30	3	:	:	PUNCT
biomedich-1001	30	4	27	27	NUM
biomedich-1001	30	5	november	november	PROPN
biomedich-1001	30	6	,	,	PUNCT
biomedich-1001	30	7	2025	2025	NUM
biomedich-1001	30	8	.	.	PUNCT
biomedich-1001	31	1	published	publish	VERB
biomedich-1001	31	2	:	:	PUNCT
biomedich-1001	31	3	12	12	NUM
biomedich-1001	31	4	december	december	NOUN
biomedich-1001	31	5	,	,	PUNCT
biomedich-1001	31	6	2025	2025	NUM
biomedich-1001	31	7	.	.	PUNCT
biomedich-1001	32	1	https://doi.org/10.14421/biomedich.2025.142.1247-1256	https://doi.org/10.14421/biomedich.2025.142.1247-1256	PROPN
biomedich-1001	32	2	1248	1248	NUM
biomedich-1001	32	3	biology	biology	NOUN
biomedich-1001	32	4	,	,	PUNCT
biomedich-1001	32	5	medicine	medicine	NOUN
biomedich-1001	32	6	,	,	PUNCT
biomedich-1001	32	7	&	&	CCONJ
biomedich-1001	32	8	natural	natural	ADJ
biomedich-1001	32	9	product	product	NOUN
biomedich-1001	32	10	chemistry	chemistry	NOUN
biomedich-1001	32	11	14	14	NUM
biomedich-1001	32	12	(	(	PUNCT
biomedich-1001	32	13	2	2	NUM
biomedich-1001	32	14	)	)	PUNCT
biomedich-1001	32	15	,	,	PUNCT
biomedich-1001	32	16	2025	2025	NUM
biomedich-1001	32	17	:	:	PUNCT
biomedich-1001	32	18	1247	1247	NUM
biomedich-1001	32	19	-	-	SYM
biomedich-1001	32	20	1256	1256	NUM
biomedich-1001	32	21	regarding	regard	VERB
biomedich-1001	32	22	their	their	PRON
biomedich-1001	32	23	ability	ability	NOUN
biomedich-1001	32	24	to	to	PART
biomedich-1001	32	25	inhibit	inhibit	VERB
biomedich-1001	32	26	xo	xo	PROPN
biomedich-1001	32	27	and	and	CCONJ
biomedich-1001	32	28	their	their	PRON
biomedich-1001	32	29	potential	potential	ADJ
biomedich-1001	32	30	use	use	NOUN
biomedich-1001	32	31	in	in	ADP
biomedich-1001	32	32	treating	treat	VERB
biomedich-1001	32	33	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	32	34	.	.	PUNCT
biomedich-1001	33	1	advances	advance	NOUN
biomedich-1001	33	2	in	in	ADP
biomedich-1001	33	3	computational	computational	ADJ
biomedich-1001	33	4	pharmacology	pharmacology	NOUN
biomedich-1001	33	5	,	,	PUNCT
biomedich-1001	33	6	particularly	particularly	ADV
biomedich-1001	33	7	in	in	ADP
biomedich-1001	33	8	molecular	molecular	ADJ
biomedich-1001	33	9	docking	docking	NOUN
biomedich-1001	33	10	and	and	CCONJ
biomedich-1001	33	11	molecular	molecular	ADJ
biomedich-1001	33	12	dynamics	dynamic	NOUN
biomedich-1001	33	13	(	(	PUNCT
biomedich-1001	33	14	md	md	NOUN
biomedich-1001	33	15	)	)	PUNCT
biomedich-1001	33	16	simulations	simulation	NOUN
biomedich-1001	33	17	,	,	PUNCT
biomedich-1001	33	18	have	have	AUX
biomedich-1001	33	19	made	make	VERB
biomedich-1001	33	20	it	it	PRON
biomedich-1001	33	21	possible	possible	ADJ
biomedich-1001	33	22	to	to	PART
biomedich-1001	33	23	accurately	accurately	ADV
biomedich-1001	33	24	model	model	VERB
biomedich-1001	33	25	how	how	SCONJ
biomedich-1001	33	26	phytochemicals	phytochemical	NOUN
biomedich-1001	33	27	interact	interact	VERB
biomedich-1001	33	28	with	with	ADP
biomedich-1001	33	29	target	target	NOUN
biomedich-1001	33	30	enzymes	enzyme	NOUN
biomedich-1001	33	31	such	such	ADJ
biomedich-1001	33	32	as	as	ADP
biomedich-1001	33	33	xo	xo	PROPN
biomedich-1001	33	34	.	.	PROPN
biomedich-1001	33	35	advances	advance	NOUN
biomedich-1001	33	36	in	in	ADP
biomedich-1001	33	37	computational	computational	ADJ
biomedich-1001	33	38	pharmacology	pharmacology	NOUN
biomedich-1001	33	39	,	,	PUNCT
biomedich-1001	33	40	particularly	particularly	ADV
biomedich-1001	33	41	in	in	ADP
biomedich-1001	33	42	molecular	molecular	ADJ
biomedich-1001	33	43	docking	docking	NOUN
biomedich-1001	33	44	and	and	CCONJ
biomedich-1001	33	45	molecular	molecular	ADJ
biomedich-1001	33	46	dynamics	dynamic	NOUN
biomedich-1001	33	47	(	(	PUNCT
biomedich-1001	33	48	md	md	NOUN
biomedich-1001	33	49	)	)	PUNCT
biomedich-1001	33	50	simulations	simulation	NOUN
biomedich-1001	33	51	,	,	PUNCT
biomedich-1001	33	52	have	have	AUX
biomedich-1001	33	53	made	make	VERB
biomedich-1001	33	54	it	it	PRON
biomedich-1001	33	55	possible	possible	ADJ
biomedich-1001	33	56	to	to	PART
biomedich-1001	33	57	accurately	accurately	ADV
biomedich-1001	33	58	model	model	VERB
biomedich-1001	33	59	how	how	SCONJ
biomedich-1001	33	60	phytochemicals	phytochemical	NOUN
biomedich-1001	33	61	interact	interact	VERB
biomedich-1001	33	62	with	with	ADP
biomedich-1001	33	63	target	target	NOUN
biomedich-1001	33	64	enzymes	enzyme	NOUN
biomedich-1001	33	65	such	such	ADJ
biomedich-1001	33	66	as	as	ADP
biomedich-1001	33	67	xo	xo	PROPN
biomedich-1001	33	68	(	(	PUNCT
biomedich-1001	33	69	mekky	mekky	PROPN
biomedich-1001	33	70	et	et	PROPN
biomedich-1001	33	71	al	al	PROPN
biomedich-1001	33	72	.	.	PROPN
biomedich-1001	33	73	,	,	PUNCT
biomedich-1001	33	74	2023	2023	NUM
biomedich-1001	33	75	)	)	PUNCT
biomedich-1001	33	76	.	.	PUNCT
biomedich-1001	34	1	this	this	DET
biomedich-1001	34	2	study	study	NOUN
biomedich-1001	34	3	seeks	seek	VERB
biomedich-1001	34	4	to	to	PART
biomedich-1001	34	5	examine	examine	VERB
biomedich-1001	34	6	the	the	DET
biomedich-1001	34	7	ability	ability	NOUN
biomedich-1001	34	8	of	of	ADP
biomedich-1001	34	9	phytochemical	phytochemical	ADJ
biomedich-1001	34	10	compounds	compound	NOUN
biomedich-1001	34	11	found	find	VERB
biomedich-1001	34	12	in	in	ADP
biomedich-1001	34	13	the	the	DET
biomedich-1001	34	14	leaves	leave	NOUN
biomedich-1001	34	15	of	of	ADP
biomedich-1001	34	16	wurfbainia	wurfbainia	PROPN
biomedich-1001	34	17	compacta	compacta	PROPN
biomedich-1001	34	18	to	to	PART
biomedich-1001	34	19	act	act	VERB
biomedich-1001	34	20	as	as	ADP
biomedich-1001	34	21	natural	natural	ADJ
biomedich-1001	34	22	inhibitors	inhibitor	NOUN
biomedich-1001	34	23	of	of	ADP
biomedich-1001	34	24	xanthine	xanthine	NOUN
biomedich-1001	34	25	oxidase	oxidase	NOUN
biomedich-1001	34	26	,	,	PUNCT
biomedich-1001	34	27	using	use	VERB
biomedich-1001	34	28	a	a	DET
biomedich-1001	34	29	combined	combine	VERB
biomedich-1001	34	30	in	in	ADP
biomedich-1001	34	31	silico	silico	NOUN
biomedich-1001	34	32	method	method	NOUN
biomedich-1001	34	33	that	that	PRON
biomedich-1001	34	34	includes	include	VERB
biomedich-1001	34	35	molecular	molecular	ADJ
biomedich-1001	34	36	docking	docking	NOUN
biomedich-1001	34	37	and	and	CCONJ
biomedich-1001	34	38	molecular	molecular	ADJ
biomedich-1001	34	39	dynamics	dynamic	NOUN
biomedich-1001	34	40	simulation	simulation	NOUN
biomedich-1001	34	41	.	.	PUNCT
biomedich-1001	35	1	the	the	DET
biomedich-1001	35	2	results	result	NOUN
biomedich-1001	35	3	could	could	AUX
biomedich-1001	35	4	help	help	VERB
biomedich-1001	35	5	in	in	ADP
biomedich-1001	35	6	identifying	identify	VERB
biomedich-1001	35	7	new	new	ADJ
biomedich-1001	35	8	plant	plant	NOUN
biomedich-1001	35	9	-	-	PUNCT
biomedich-1001	35	10	based	base	VERB
biomedich-1001	35	11	treatments	treatment	NOUN
biomedich-1001	35	12	for	for	ADP
biomedich-1001	35	13	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	35	14	that	that	PRON
biomedich-1001	35	15	offer	offer	VERB
biomedich-1001	35	16	better	well	ADJ
biomedich-1001	35	17	safety	safety	NOUN
biomedich-1001	35	18	.	.	PUNCT
biomedich-1001	36	1	materials	material	NOUN
biomedich-1001	36	2	and	and	CCONJ
biomedich-1001	36	3	methods	method	NOUN
biomedich-1001	36	4	materials	material	NOUN
biomedich-1001	36	5	chemdraw	chemdraw	VERB
biomedich-1001	36	6	ultra	ultra	ADJ
biomedich-1001	36	7	8.0	8.0	NUM
biomedich-1001	36	8	from	from	ADP
biomedich-1001	36	9	cambridge	cambridge	PROPN
biomedich-1001	36	10	soft	soft	ADJ
biomedich-1001	36	11	corporation	corporation	NOUN
biomedich-1001	36	12	2003	2003	NUM
biomedich-1001	36	13	8	8	NUM
biomedich-1001	36	14	versions	version	NOUN
biomedich-1001	36	15	,	,	PUNCT
biomedich-1001	36	16	marvin	marvin	PROPN
biomedich-1001	36	17	sketch	sketch	PROPN
biomedich-1001	36	18	from	from	ADP
biomedich-1001	36	19	chemaxon	chemaxon	NOUN
biomedich-1001	36	20	1999	1999	NUM
biomedich-1001	36	21	23.1	23.1	NUM
biomedich-1001	36	22	version	version	NOUN
biomedich-1001	36	23	,	,	PUNCT
biomedich-1001	36	24	molegro	molegro	ADJ
biomedich-1001	36	25	molecular	molecular	ADJ
biomedich-1001	36	26	view	view	NOUN
biomedich-1001	36	27	2008	2008	NUM
biomedich-1001	36	28	2.5	2.5	NUM
biomedich-1001	36	29	version	version	NOUN
biomedich-1001	36	30	,	,	PUNCT
biomedich-1001	36	31	autodock	autodock	NOUN
biomedich-1001	36	32	from	from	ADP
biomedich-1001	36	33	molecular	molecular	ADJ
biomedich-1001	36	34	graphics	graphic	NOUN
biomedich-1001	36	35	laboratory	laboratory	NOUN
biomedich-1001	36	36	tools	tool	NOUN
biomedich-1001	36	37	1.5.6	1.5.6	NUM
biomedich-1001	36	38	version	version	NOUN
biomedich-1001	36	39	,	,	PUNCT
biomedich-1001	36	40	biovia	biovia	PROPN
biomedich-1001	36	41	discovery	discovery	PROPN
biomedich-1001	36	42	studio	studio	PROPN
biomedich-1001	36	43	and	and	CCONJ
biomedich-1001	36	44	desmond	desmond	PROPN
biomedich-1001	36	45	(	(	PUNCT
biomedich-1001	36	46	dassault	dassault	NOUN
biomedich-1001	36	47	systemes	systeme	NOUN
biomedich-1001	36	48	)	)	PUNCT
biomedich-1001	36	49	were	be	AUX
biomedich-1001	36	50	utilized	utilize	VERB
biomedich-1001	36	51	.	.	PUNCT
biomedich-1001	37	1	web	web	NOUN
biomedich-1001	37	2	servers	server	NOUN
biomedich-1001	37	3	include	include	VERB
biomedich-1001	37	4	rcsb	rcsb	NOUN
biomedich-1001	37	5	pdb	pdb	PROPN
biomedich-1001	37	6	,	,	PUNCT
biomedich-1001	37	7	pdbsum	pdbsum	NOUN
biomedich-1001	37	8	,	,	PUNCT
biomedich-1001	37	9	and	and	CCONJ
biomedich-1001	37	10	preadmet	preadmet	NOUN
biomedich-1001	37	11	.	.	PUNCT
biomedich-1001	38	1	a	a	DET
biomedich-1001	38	2	personal	personal	ADJ
biomedich-1001	38	3	computer	computer	NOUN
biomedich-1001	38	4	with	with	ADP
biomedich-1001	38	5	linux	linux	PROPN
biomedich-1001	38	6	ubuntu	ubuntu	PROPN
biomedich-1001	38	7	18.04.5	18.04.5	PROPN
biomedich-1001	38	8	lts	lt	VERB
biomedich-1001	38	9	64	64	NUM
biomedich-1001	38	10	-	-	PUNCT
biomedich-1001	38	11	bit	bit	NOUN
biomedich-1001	38	12	,	,	PUNCT
biomedich-1001	38	13	processor	processor	NOUN
biomedich-1001	38	14	intel	intel	PROPN
biomedich-1001	38	15	®	®	PROPN
biomedich-1001	38	16	coretm	coretm	NOUN
biomedich-1001	38	17	i5	i5	PROPN
biomedich-1001	38	18	-	-	PUNCT
biomedich-1001	38	19	8400	8400	NUM
biomedich-1001	38	20	cpu	cpu	NOUN
biomedich-1001	38	21	@	@	ADP
biomedich-1001	38	22	2.80ghz	2.80ghz	NUM
biomedich-1001	38	23	x	x	SYM
biomedich-1001	38	24	6	6	NUM
biomedich-1001	38	25	,	,	PUNCT
biomedich-1001	38	26	memory	memory	NOUN
biomedich-1001	38	27	7,7	7,7	NUM
biomedich-1001	38	28	gib	gib	NOUN
biomedich-1001	38	29	,	,	PUNCT
biomedich-1001	38	30	graphics	graphic	NOUN
biomedich-1001	38	31	geforce	geforce	NOUN
biomedich-1001	38	32	gtx	gtx	PROPN
biomedich-1001	38	33	970	970	NUM
biomedich-1001	38	34	/	/	SYM
biomedich-1001	38	35	pcie	pcie	NOUN
biomedich-1001	38	36	/	/	SYM
biomedich-1001	38	37	sse2	sse2	NOUN
biomedich-1001	38	38	,	,	PUNCT
biomedich-1001	38	39	gnome	gnome	NOUN
biomedich-1001	38	40	3.28.2	3.28.2	NUM
biomedich-1001	38	41	,	,	PUNCT
biomedich-1001	38	42	disk	disk	NOUN
biomedich-1001	38	43	245,1	245,1	NUM
biomedich-1001	38	44	gb	gb	NOUN
biomedich-1001	38	45	.	.	PUNCT
biomedich-1001	38	46	plant	plant	NOUN
biomedich-1001	38	47	material	material	NOUN
biomedich-1001	38	48	and	and	CCONJ
biomedich-1001	38	49	protein	protein	NOUN
biomedich-1001	38	50	:	:	PUNCT
biomedich-1001	38	51	50	50	NUM
biomedich-1001	38	52	cardamom	cardamom	NOUN
biomedich-1001	38	53	leaves	leave	VERB
biomedich-1001	38	54	compounds	compound	NOUN
biomedich-1001	38	55	from	from	ADP
biomedich-1001	38	56	the	the	DET
biomedich-1001	38	57	literature	literature	NOUN
biomedich-1001	38	58	were	be	AUX
biomedich-1001	38	59	used	use	VERB
biomedich-1001	38	60	,	,	PUNCT
biomedich-1001	38	61	and	and	CCONJ
biomedich-1001	38	62	a	a	DET
biomedich-1001	38	63	receptor	receptor	NOUN
biomedich-1001	38	64	protein	protein	NOUN
biomedich-1001	38	65	with	with	ADP
biomedich-1001	38	66	pdb	pdb	PROPN
biomedich-1001	38	67	i	i	PROPN
biomedich-1001	38	68	d	d	PROPN
biomedich-1001	38	69	code	code	PROPN
biomedich-1001	39	1	3nvw	3nvw	ADV
biomedich-1001	39	2	and	and	CCONJ
biomedich-1001	39	3	allopurinol	allopurinol	NOUN
biomedich-1001	39	4	were	be	AUX
biomedich-1001	39	5	used	use	VERB
biomedich-1001	39	6	as	as	ADP
biomedich-1001	39	7	positive	positive	ADJ
biomedich-1001	39	8	control	control	NOUN
biomedich-1001	39	9	drugs	drug	NOUN
biomedich-1001	39	10	.	.	PUNCT
biomedich-1001	40	1	procedures	procedure	NOUN
biomedich-1001	40	2	receptor	receptor	NOUN
biomedich-1001	40	3	identification	identification	NOUN
biomedich-1001	40	4	receptors	receptor	NOUN
biomedich-1001	40	5	were	be	AUX
biomedich-1001	40	6	obtained	obtain	VERB
biomedich-1001	40	7	from	from	ADP
biomedich-1001	40	8	the	the	DET
biomedich-1001	40	9	website	website	NOUN
biomedich-1001	40	10	https://www.rcsb.org/.	https://www.rcsb.org/.	VERB
biomedich-1001	40	11	a	a	DET
biomedich-1001	40	12	receptor	receptor	NOUN
biomedich-1001	40	13	with	with	ADP
biomedich-1001	40	14	a	a	DET
biomedich-1001	40	15	resolution	resolution	NOUN
biomedich-1001	40	16	of	of	ADP
biomedich-1001	40	17	less	less	ADJ
biomedich-1001	40	18	than	than	ADP
biomedich-1001	40	19	2å	2å	NUM
biomedich-1001	40	20	and	and	CCONJ
biomedich-1001	40	21	a	a	DET
biomedich-1001	40	22	natural	natural	ADJ
biomedich-1001	40	23	ligand	ligand	NOUN
biomedich-1001	40	24	similar	similar	ADJ
biomedich-1001	40	25	in	in	ADP
biomedich-1001	40	26	structure	structure	NOUN
biomedich-1001	40	27	to	to	ADP
biomedich-1001	40	28	the	the	DET
biomedich-1001	40	29	reference	reference	NOUN
biomedich-1001	40	30	drug	drug	NOUN
biomedich-1001	40	31	was	be	AUX
biomedich-1001	40	32	chosen	choose	VERB
biomedich-1001	40	33	.	.	PUNCT
biomedich-1001	41	1	the	the	DET
biomedich-1001	41	2	receptor	receptor	NOUN
biomedich-1001	41	3	was	be	AUX
biomedich-1001	41	4	then	then	ADV
biomedich-1001	41	5	examined	examine	VERB
biomedich-1001	41	6	on	on	ADP
biomedich-1001	41	7	the	the	DET
biomedich-1001	41	8	http://www.ebj.ac.uk/pdbsum	http://www.ebj.ac.uk/pdbsum	NOUN
biomedich-1001	41	9	site	site	NOUN
biomedich-1001	41	10	to	to	PART
biomedich-1001	41	11	confirm	confirm	VERB
biomedich-1001	41	12	that	that	SCONJ
biomedich-1001	41	13	it	it	PRON
biomedich-1001	41	14	aligned	align	VERB
biomedich-1001	41	15	with	with	ADP
biomedich-1001	41	16	the	the	DET
biomedich-1001	41	17	ramachandran	ramachandran	PROPN
biomedich-1001	41	18	plot	plot	NOUN
biomedich-1001	41	19	(	(	PUNCT
biomedich-1001	41	20	ruswanto	ruswanto	NOUN
biomedich-1001	41	21	et	et	PROPN
biomedich-1001	41	22	al	al	PROPN
biomedich-1001	41	23	.	.	PROPN
biomedich-1001	41	24	,	,	PUNCT
biomedich-1001	41	25	2018	2018	NUM
biomedich-1001	41	26	)	)	PUNCT
biomedich-1001	41	27	.	.	PUNCT
biomedich-1001	42	1	docking	dock	VERB
biomedich-1001	42	2	validations	validation	NOUN
biomedich-1001	42	3	docking	dock	VERB
biomedich-1001	42	4	validation	validation	NOUN
biomedich-1001	42	5	was	be	AUX
biomedich-1001	42	6	performed	perform	VERB
biomedich-1001	42	7	to	to	PART
biomedich-1001	42	8	develop	develop	VERB
biomedich-1001	42	9	a	a	DET
biomedich-1001	42	10	reliable	reliable	ADJ
biomedich-1001	42	11	method	method	NOUN
biomedich-1001	42	12	by	by	ADP
biomedich-1001	42	13	repeatedly	repeatedly	ADV
biomedich-1001	42	14	docking	dock	VERB
biomedich-1001	42	15	the	the	DET
biomedich-1001	42	16	original	original	ADJ
biomedich-1001	42	17	ligand	ligand	NOUN
biomedich-1001	42	18	to	to	ADP
biomedich-1001	42	19	the	the	DET
biomedich-1001	42	20	target	target	NOUN
biomedich-1001	42	21	protein	protein	NOUN
biomedich-1001	42	22	using	use	VERB
biomedich-1001	42	23	autodocktools	autodocktool	NOUN
biomedich-1001	42	24	(	(	PUNCT
biomedich-1001	42	25	sari	sari	NOUN
biomedich-1001	42	26	et	et	PROPN
biomedich-1001	42	27	al	al	PROPN
biomedich-1001	42	28	.	.	PROPN
biomedich-1001	42	29	,	,	PUNCT
biomedich-1001	42	30	2020	2020	NUM
biomedich-1001	42	31	)	)	PUNCT
biomedich-1001	42	32	.	.	PUNCT
biomedich-1001	43	1	ligand	ligand	PROPN
biomedich-1001	43	2	preparation	preparation	NOUN
biomedich-1001	43	3	the	the	DET
biomedich-1001	43	4	ligands	ligand	NOUN
biomedich-1001	43	5	were	be	AUX
biomedich-1001	43	6	protonated	protonate	VERB
biomedich-1001	43	7	by	by	ADP
biomedich-1001	43	8	adding	add	VERB
biomedich-1001	43	9	protons	proton	NOUN
biomedich-1001	43	10	(	(	PUNCT
biomedich-1001	43	11	h	h	NOUN
biomedich-1001	43	12	)	)	PUNCT
biomedich-1001	43	13	and	and	CCONJ
biomedich-1001	43	14	simulating	simulate	VERB
biomedich-1001	43	15	a	a	DET
biomedich-1001	43	16	specific	specific	ADJ
biomedich-1001	43	17	ph	ph	ADJ
biomedich-1001	43	18	level	level	NOUN
biomedich-1001	43	19	to	to	PART
biomedich-1001	43	20	match	match	VERB
biomedich-1001	43	21	the	the	DET
biomedich-1001	43	22	ph	ph	NOUN
biomedich-1001	43	23	of	of	ADP
biomedich-1001	43	24	the	the	DET
biomedich-1001	43	25	human	human	ADJ
biomedich-1001	43	26	body	body	NOUN
biomedich-1001	43	27	,	,	PUNCT
biomedich-1001	43	28	which	which	PRON
biomedich-1001	43	29	is	be	AUX
biomedich-1001	43	30	7.4	7.4	NUM
biomedich-1001	43	31	.	.	PUNCT
biomedich-1001	44	1	the	the	DET
biomedich-1001	44	2	resulting	result	VERB
biomedich-1001	44	3	file	file	NOUN
biomedich-1001	44	4	was	be	AUX
biomedich-1001	44	5	saved	save	VERB
biomedich-1001	44	6	in	in	ADP
biomedich-1001	44	7	.mrv	.mrv	NOUN
biomedich-1001	44	8	format	format	NOUN
biomedich-1001	44	9	.	.	PUNCT
biomedich-1001	45	1	the	the	DET
biomedich-1001	45	2	next	next	ADJ
biomedich-1001	45	3	step	step	NOUN
biomedich-1001	45	4	involved	involve	VERB
biomedich-1001	45	5	conducting	conduct	VERB
biomedich-1001	45	6	a	a	DET
biomedich-1001	45	7	conformational	conformational	ADJ
biomedich-1001	45	8	search	search	NOUN
biomedich-1001	45	9	,	,	PUNCT
biomedich-1001	45	10	and	and	CCONJ
biomedich-1001	45	11	the	the	DET
biomedich-1001	45	12	file	file	NOUN
biomedich-1001	45	13	was	be	AUX
biomedich-1001	45	14	then	then	ADV
biomedich-1001	45	15	saved	save	VERB
biomedich-1001	45	16	in	in	ADP
biomedich-1001	45	17	.mol2	.mol2	PROPN
biomedich-1001	45	18	format	format	NOUN
biomedich-1001	45	19	.	.	PUNCT
biomedich-1001	46	1	it	it	PRON
biomedich-1001	46	2	was	be	AUX
biomedich-1001	46	3	imported	import	VERB
biomedich-1001	46	4	into	into	ADP
biomedich-1001	46	5	the	the	DET
biomedich-1001	46	6	molegro	molegro	ADJ
biomedich-1001	46	7	molecular	molecular	ADJ
biomedich-1001	46	8	viewer	viewer	NOUN
biomedich-1001	46	9	,	,	PUNCT
biomedich-1001	46	10	and	and	CCONJ
biomedich-1001	46	11	subsequently	subsequently	ADV
biomedich-1001	46	12	,	,	PUNCT
biomedich-1001	46	13	the	the	DET
biomedich-1001	46	14	molecule	molecule	NOUN
biomedich-1001	46	15	was	be	AUX
biomedich-1001	46	16	exported	export	VERB
biomedich-1001	46	17	in	in	ADP
biomedich-1001	46	18	.pdb	.pdb	PUNCT
biomedich-1001	46	19	format	format	NOUN
biomedich-1001	46	20	(	(	PUNCT
biomedich-1001	46	21	sagitasa	sagitasa	NOUN
biomedich-1001	46	22	et	et	PROPN
biomedich-1001	46	23	al	al	PROPN
biomedich-1001	46	24	.	.	PROPN
biomedich-1001	46	25	,	,	PUNCT
biomedich-1001	46	26	2021	2021	NUM
biomedich-1001	46	27	)	)	PUNCT
biomedich-1001	46	28	.	.	PUNCT
biomedich-1001	47	1	figure	figure	NOUN
biomedich-1001	47	2	1	1	NUM
biomedich-1001	47	3	.	.	PUNCT
biomedich-1001	47	4	2d	2d	NUM
biomedich-1001	47	5	visualization	visualization	NOUN
biomedich-1001	47	6	of	of	ADP
biomedich-1001	47	7	the	the	DET
biomedich-1001	47	8	redocking	redocking	NOUN
biomedich-1001	47	9	results	result	NOUN
biomedich-1001	47	10	of	of	ADP
biomedich-1001	47	11	receptor	receptor	NOUN
biomedich-1001	47	12	3nvw	3nvw	ADJ
biomedich-1001	47	13	prediction	prediction	NOUN
biomedich-1001	47	14	of	of	ADP
biomedich-1001	47	15	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	47	16	and	and	CCONJ
biomedich-1001	47	17	toxicity	toxicity	NOUN
biomedich-1001	47	18	toxicity	toxicity	NOUN
biomedich-1001	47	19	and	and	CCONJ
biomedich-1001	47	20	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	47	21	tests	test	NOUN
biomedich-1001	47	22	were	be	AUX
biomedich-1001	47	23	conducted	conduct	VERB
biomedich-1001	47	24	using	use	VERB
biomedich-1001	47	25	the	the	DET
biomedich-1001	47	26	preadmet	preadmet	NOUN
biomedich-1001	47	27	website	website	NOUN
biomedich-1001	47	28	.	.	PUNCT
biomedich-1001	48	1	the	the	DET
biomedich-1001	48	2	results	result	NOUN
biomedich-1001	48	3	included	include	VERB
biomedich-1001	48	4	analysis	analysis	NOUN
biomedich-1001	48	5	of	of	ADP
biomedich-1001	48	6	the	the	DET
biomedich-1001	48	7	ames	ames	PROPN
biomedich-1001	48	8	test	test	NOUN
biomedich-1001	48	9	,	,	PUNCT
biomedich-1001	48	10	carcinogenity	carcinogenity	NOUN
biomedich-1001	48	11	in	in	ADP
biomedich-1001	48	12	mice	mouse	NOUN
biomedich-1001	48	13	,	,	PUNCT
biomedich-1001	48	14	carcinogenity	carcinogenity	NOUN
biomedich-1001	48	15	in	in	ADP
biomedich-1001	48	16	rats	rat	NOUN
biomedich-1001	48	17	,	,	PUNCT
biomedich-1001	48	18	hia	hia	PROPN
biomedich-1001	48	19	,	,	PUNCT
biomedich-1001	48	20	caco-2	caco-2	NOUN
biomedich-1001	48	21	,	,	PUNCT
biomedich-1001	48	22	and	and	CCONJ
biomedich-1001	48	23	ppb	ppb	NOUN
biomedich-1001	48	24	parameters	parameter	NOUN
biomedich-1001	48	25	were	be	AUX
biomedich-1001	48	26	reviewed	review	VERB
biomedich-1001	48	27	(	(	PUNCT
biomedich-1001	48	28	mardianingrum	mardianingrum	NOUN
biomedich-1001	48	29	et	et	PROPN
biomedich-1001	48	30	al	al	PROPN
biomedich-1001	48	31	.	.	PROPN
biomedich-1001	48	32	,	,	PUNCT
biomedich-1001	48	33	2021	2021	NUM
biomedich-1001	48	34	)	)	PUNCT
biomedich-1001	48	35	.	.	PUNCT
biomedich-1001	49	1	drug	drug	NOUN
biomedich-1001	49	2	scan	scan	VERB
biomedich-1001	49	3	a	a	DET
biomedich-1001	49	4	drug	drug	NOUN
biomedich-1001	49	5	screening	screening	NOUN
biomedich-1001	49	6	process	process	NOUN
biomedich-1001	49	7	was	be	AUX
biomedich-1001	49	8	conducted	conduct	VERB
biomedich-1001	49	9	using	use	VERB
biomedich-1001	49	10	lipinski	lipinski	PROPN
biomedich-1001	49	11	’s	’s	PART
biomedich-1001	49	12	program	program	NOUN
biomedich-1001	49	13	to	to	PART
biomedich-1001	49	14	assess	assess	VERB
biomedich-1001	49	15	how	how	SCONJ
biomedich-1001	49	16	similar	similar	ADJ
biomedich-1001	49	17	a	a	DET
biomedich-1001	49	18	compound	compound	NOUN
biomedich-1001	49	19	is	be	AUX
biomedich-1001	49	20	to	to	ADP
biomedich-1001	49	21	a	a	DET
biomedich-1001	49	22	reference	reference	NOUN
biomedich-1001	49	23	drug	drug	NOUN
biomedich-1001	49	24	based	base	VERB
biomedich-1001	49	25	on	on	ADP
biomedich-1001	49	26	the	the	DET
biomedich-1001	49	27	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	49	28	processes	process	NOUN
biomedich-1001	49	29	that	that	PRON
biomedich-1001	49	30	take	take	VERB
biomedich-1001	49	31	place	place	NOUN
biomedich-1001	49	32	in	in	ADP
biomedich-1001	49	33	the	the	DET
biomedich-1001	49	34	body	body	NOUN
biomedich-1001	49	35	.	.	PUNCT
biomedich-1001	50	1	the	the	DET
biomedich-1001	50	2	parameter	parameter	NOUN
biomedich-1001	50	3	examined	examine	VERB
biomedich-1001	50	4	during	during	ADP
biomedich-1001	50	5	this	this	DET
biomedich-1001	50	6	stage	stage	NOUN
biomedich-1001	50	7	was	be	AUX
biomedich-1001	50	8	log	log	NOUN
biomedich-1001	50	9	p	p	NOUN
biomedich-1001	50	10	(	(	PUNCT
biomedich-1001	50	11	rahmawaty	rahmawaty	NOUN
biomedich-1001	50	12	et	et	PROPN
biomedich-1001	50	13	al	al	PROPN
biomedich-1001	50	14	.	.	PROPN
biomedich-1001	50	15	,	,	PUNCT
biomedich-1001	50	16	2022	2022	NUM
biomedich-1001	50	17	)	)	PUNCT
biomedich-1001	50	18	.	.	PUNCT
biomedich-1001	51	1	molecular	molecular	ADJ
biomedich-1001	51	2	docking	docking	NOUN
biomedich-1001	51	3	and	and	CCONJ
biomedich-1001	51	4	visualization	visualization	NOUN
biomedich-1001	51	5	the	the	DET
biomedich-1001	51	6	process	process	NOUN
biomedich-1001	51	7	was	be	AUX
biomedich-1001	51	8	conducted	conduct	VERB
biomedich-1001	51	9	using	use	VERB
biomedich-1001	51	10	autodock	autodock	NOUN
biomedich-1001	51	11	to	to	PART
biomedich-1001	51	12	dock	dock	VERB
biomedich-1001	51	13	the	the	DET
biomedich-1001	51	14	test	test	NOUN
biomedich-1001	51	15	ligand	ligand	NOUN
biomedich-1001	51	16	onto	onto	ADP
biomedich-1001	51	17	the	the	DET
biomedich-1001	51	18	target	target	NOUN
biomedich-1001	51	19	receptor	receptor	NOUN
biomedich-1001	51	20	,	,	PUNCT
biomedich-1001	51	21	with	with	ADP
biomedich-1001	51	22	the	the	DET
biomedich-1001	51	23	grid	grid	NOUN
biomedich-1001	51	24	dimensions	dimension	NOUN
biomedich-1001	51	25	based	base	VERB
biomedich-1001	51	26	on	on	ADP
biomedich-1001	51	27	the	the	DET
biomedich-1001	51	28	validation	validation	NOUN
biomedich-1001	51	29	results	result	NOUN
biomedich-1001	51	30	for	for	ADP
biomedich-1001	51	31	the	the	DET
biomedich-1001	51	32	x	x	PROPN
biomedich-1001	51	33	,	,	PUNCT
biomedich-1001	51	34	y	y	PROPN
biomedich-1001	51	35	,	,	PUNCT
biomedich-1001	51	36	and	and	CCONJ
biomedich-1001	51	37	z	z	NOUN
biomedich-1001	51	38	axes	axis	NOUN
biomedich-1001	51	39	,	,	PUNCT
biomedich-1001	51	40	which	which	PRON
biomedich-1001	51	41	were	be	AUX
biomedich-1001	51	42	38.017	38.017	NUM
biomedich-1001	51	43	,	,	PUNCT
biomedich-1001	51	44	20.172	20.172	NUM
biomedich-1001	51	45	,	,	PUNCT
biomedich-1001	51	46	and	and	CCONJ
biomedich-1001	51	47	18.698	18.698	NUM
biomedich-1001	51	48	,	,	PUNCT
biomedich-1001	51	49	respectively	respectively	ADV
biomedich-1001	51	50	(	(	PUNCT
biomedich-1001	51	51	dermawan	dermawan	NOUN
biomedich-1001	51	52	et	et	PROPN
biomedich-1001	51	53	al	al	PROPN
biomedich-1001	51	54	.	.	PROPN
biomedich-1001	51	55	,	,	PUNCT
biomedich-1001	51	56	2019	2019	NUM
biomedich-1001	51	57	)	)	PUNCT
biomedich-1001	51	58	.	.	PUNCT
biomedich-1001	52	1	the	the	DET
biomedich-1001	52	2	outcomes	outcome	NOUN
biomedich-1001	52	3	were	be	AUX
biomedich-1001	52	4	presented	present	VERB
biomedich-1001	52	5	as	as	ADP
biomedich-1001	52	6	binding	bind	VERB
biomedich-1001	52	7	energy	energy	NOUN
biomedich-1001	52	8	(	(	PUNCT
biomedich-1001	52	9	δg	δg	NOUN
biomedich-1001	52	10	)	)	PUNCT
biomedich-1001	52	11	and	and	CCONJ
biomedich-1001	52	12	inhibition	inhibition	VERB
biomedich-1001	52	13	constant	constant	ADJ
biomedich-1001	52	14	(	(	PUNCT
biomedich-1001	52	15	ki	ki	PROPN
biomedich-1001	52	16	)	)	PUNCT
biomedich-1001	52	17	,	,	PUNCT
biomedich-1001	52	18	followed	follow	VERB
biomedich-1001	52	19	by	by	ADP
biomedich-1001	52	20	visualization	visualization	NOUN
biomedich-1001	52	21	to	to	PART
biomedich-1001	52	22	examine	examine	VERB
biomedich-1001	52	23	the	the	DET
biomedich-1001	52	24	possible	possible	ADJ
biomedich-1001	52	25	interactions	interaction	NOUN
biomedich-1001	52	26	between	between	ADP
biomedich-1001	52	27	the	the	DET
biomedich-1001	52	28	ligand	ligand	NOUN
biomedich-1001	52	29	and	and	CCONJ
biomedich-1001	52	30	the	the	DET
biomedich-1001	52	31	receptor	receptor	NOUN
biomedich-1001	52	32	(	(	PUNCT
biomedich-1001	52	33	ruswanto	ruswanto	NOUN
biomedich-1001	52	34	et	et	PROPN
biomedich-1001	52	35	al	al	PROPN
biomedich-1001	52	36	.	.	PROPN
biomedich-1001	52	37	,	,	PUNCT
biomedich-1001	52	38	2023	2023	NUM
biomedich-1001	52	39	)	)	PUNCT
biomedich-1001	52	40	.	.	PUNCT
biomedich-1001	53	1	molecular	molecular	ADJ
biomedich-1001	53	2	dynamic	dynamic	ADJ
biomedich-1001	53	3	simulations	simulation	NOUN
biomedich-1001	53	4	the	the	DET
biomedich-1001	53	5	simulation	simulation	NOUN
biomedich-1001	53	6	process	process	NOUN
biomedich-1001	53	7	was	be	AUX
biomedich-1001	53	8	conducted	conduct	VERB
biomedich-1001	53	9	on	on	ADP
biomedich-1001	53	10	the	the	DET
biomedich-1001	53	11	selected	select	VERB
biomedich-1001	53	12	compound	compound	NOUN
biomedich-1001	53	13	based	base	VERB
biomedich-1001	53	14	on	on	ADP
biomedich-1001	53	15	the	the	DET
biomedich-1001	53	16	docking	docking	NOUN
biomedich-1001	53	17	results	result	NOUN
biomedich-1001	53	18	with	with	ADP
biomedich-1001	53	19	the	the	DET
biomedich-1001	53	20	receptor	receptor	NOUN
biomedich-1001	53	21	using	use	VERB
biomedich-1001	53	22	the	the	DET
biomedich-1001	53	23	desmond	desmond	PROPN
biomedich-1001	53	24	software	software	NOUN
biomedich-1001	53	25	to	to	PART
biomedich-1001	53	26	investigate	investigate	VERB
biomedich-1001	53	27	the	the	DET
biomedich-1001	53	28	stability	stability	NOUN
biomedich-1001	53	29	between	between	ADP
biomedich-1001	53	30	the	the	DET
biomedich-1001	53	31	compound	compound	NOUN
biomedich-1001	53	32	and	and	CCONJ
biomedich-1001	53	33	the	the	DET
biomedich-1001	53	34	receptor	receptor	NOUN
biomedich-1001	53	35	.	.	PUNCT
biomedich-1001	54	1	the	the	DET
biomedich-1001	54	2	process	process	NOUN
biomedich-1001	54	3	began	begin	VERB
biomedich-1001	54	4	with	with	ADP
biomedich-1001	54	5	preparing	prepare	VERB
biomedich-1001	54	6	the	the	DET
biomedich-1001	54	7	test	test	NOUN
biomedich-1001	54	8	compound	compound	NOUN
biomedich-1001	54	9	and	and	CCONJ
biomedich-1001	54	10	the	the	DET
biomedich-1001	54	11	solvation	solvation	NOUN
biomedich-1001	54	12	stage	stage	NOUN
biomedich-1001	54	13	,	,	PUNCT
biomedich-1001	54	14	where	where	SCONJ
biomedich-1001	54	15	the	the	DET
biomedich-1001	54	16	ligand	ligand	ADJ
biomedich-1001	54	17	-	-	PUNCT
biomedich-1001	54	18	receptor	receptor	NOUN
biomedich-1001	54	19	complex	complex	NOUN
biomedich-1001	54	20	was	be	AUX
biomedich-1001	54	21	dissolved	dissolve	VERB
biomedich-1001	54	22	in	in	ADP
biomedich-1001	54	23	tip3p	tip3p	NOUN
biomedich-1001	54	24	-	-	PUNCT
biomedich-1001	54	25	type	type	NOUN
biomedich-1001	54	26	water	water	NOUN
biomedich-1001	54	27	.	.	PUNCT
biomedich-1001	55	1	neutralization	neutralization	NOUN
biomedich-1001	55	2	was	be	AUX
biomedich-1001	55	3	then	then	ADV
biomedich-1001	55	4	carried	carry	VERB
biomedich-1001	55	5	out	out	ADP
biomedich-1001	55	6	by	by	ADP
biomedich-1001	55	7	adding	add	VERB
biomedich-1001	55	8	na+	na+	NOUN
biomedich-1001	55	9	and	and	CCONJ
biomedich-1001	55	10	clions	clion	NOUN
biomedich-1001	55	11	to	to	PART
biomedich-1001	55	12	ensure	ensure	VERB
biomedich-1001	55	13	the	the	DET
biomedich-1001	55	14	system	system	NOUN
biomedich-1001	55	15	reached	reach	VERB
biomedich-1001	55	16	a	a	DET
biomedich-1001	55	17	neutral	neutral	ADJ
biomedich-1001	55	18	state	state	NOUN
biomedich-1001	55	19	,	,	PUNCT
biomedich-1001	55	20	mimicking	mimic	VERB
biomedich-1001	55	21	the	the	DET
biomedich-1001	55	22	physiological	physiological	ADJ
biomedich-1001	55	23	conditions	condition	NOUN
biomedich-1001	55	24	of	of	ADP
biomedich-1001	55	25	the	the	DET
biomedich-1001	55	26	human	human	ADJ
biomedich-1001	55	27	body	body	NOUN
biomedich-1001	55	28	.	.	PUNCT
biomedich-1001	56	1	next	next	ADV
biomedich-1001	56	2	,	,	PUNCT
biomedich-1001	56	3	minimizing	minimize	VERB
biomedich-1001	56	4	was	be	AUX
biomedich-1001	56	5	performed	perform	VERB
biomedich-1001	56	6	to	to	PART
biomedich-1001	56	7	reduce	reduce	VERB
biomedich-1001	56	8	the	the	DET
biomedich-1001	56	9	potential	potential	ADJ
biomedich-1001	56	10	energy	energy	NOUN
biomedich-1001	56	11	and	and	CCONJ
biomedich-1001	56	12	produce	produce	VERB
biomedich-1001	56	13	a	a	DET
biomedich-1001	56	14	more	more	ADV
biomedich-1001	56	15	stable	stable	ADJ
biomedich-1001	56	16	conformation	conformation	NOUN
biomedich-1001	56	17	by	by	ADP
biomedich-1001	56	18	avoiding	avoid	VERB
biomedich-1001	56	19	atomic	atomic	ADJ
biomedich-1001	56	20	clashes	clash	NOUN
biomedich-1001	56	21	during	during	ADP
biomedich-1001	56	22	the	the	DET
biomedich-1001	56	23	formation	formation	NOUN
biomedich-1001	56	24	or	or	CCONJ
biomedich-1001	56	25	breaking	breaking	NOUN
biomedich-1001	56	26	of	of	ADP
biomedich-1001	56	27	hydrogen	hydrogen	NOUN
biomedich-1001	56	28	bonds	bond	NOUN
biomedich-1001	56	29	.	.	PUNCT
biomedich-1001	57	1	following	follow	VERB
biomedich-1001	57	2	this	this	PRON
biomedich-1001	57	3	,	,	PUNCT
biomedich-1001	57	4	heating	heating	NOUN
biomedich-1001	57	5	was	be	AUX
biomedich-1001	57	6	applied	apply	VERB
biomedich-1001	57	7	,	,	PUNCT
biomedich-1001	57	8	with	with	ADP
biomedich-1001	57	9	temperature	temperature	NOUN
biomedich-1001	57	10	and	and	CCONJ
biomedich-1001	57	11	pressure	pressure	NOUN
biomedich-1001	57	12	adjusted	adjust	VERB
biomedich-1001	57	13	to	to	PART
biomedich-1001	57	14	match	match	VERB
biomedich-1001	57	15	the	the	DET
biomedich-1001	57	16	normal	normal	ADJ
biomedich-1001	57	17	human	human	ADJ
biomedich-1001	57	18	body	body	NOUN
biomedich-1001	57	19	temperature	temperature	NOUN
biomedich-1001	57	20	so	so	SCONJ
biomedich-1001	57	21	that	that	SCONJ
biomedich-1001	57	22	the	the	DET
biomedich-1001	57	23	protein	protein	NOUN
biomedich-1001	57	24	complex	complex	NOUN
biomedich-1001	57	25	could	could	AUX
biomedich-1001	57	26	function	function	VERB
biomedich-1001	57	27	normally	normally	ADV
biomedich-1001	57	28	during	during	ADP
biomedich-1001	57	29	the	the	DET
biomedich-1001	57	30	simulation	simulation	NOUN
biomedich-1001	57	31	.	.	PUNCT
biomedich-1001	58	1	equilibration	equilibration	NOUN
biomedich-1001	58	2	was	be	AUX
biomedich-1001	58	3	then	then	ADV
biomedich-1001	58	4	performed	perform	VERB
biomedich-1001	58	5	,	,	PUNCT
biomedich-1001	58	6	where	where	SCONJ
biomedich-1001	58	7	the	the	DET
biomedich-1001	58	8	system	system	NOUN
biomedich-1001	58	9	reached	reach	VERB
biomedich-1001	58	10	a	a	DET
biomedich-1001	58	11	constant	constant	ADJ
biomedich-1001	58	12	state	state	NOUN
biomedich-1001	58	13	of	of	ADP
biomedich-1001	58	14	temperature	temperature	NOUN
biomedich-1001	58	15	,	,	PUNCT
biomedich-1001	58	16	volume	volume	NOUN
biomedich-1001	58	17	,	,	PUNCT
biomedich-1001	58	18	and	and	CCONJ
biomedich-1001	58	19	pressure	pressure	NOUN
biomedich-1001	58	20	.	.	PUNCT
biomedich-1001	59	1	the	the	DET
biomedich-1001	59	2	simulation	simulation	NOUN
biomedich-1001	59	3	was	be	AUX
biomedich-1001	59	4	run	run	VERB
biomedich-1001	59	5	for	for	ADP
biomedich-1001	59	6	100	100	NUM
biomedich-1001	59	7	nanoseconds	nanosecond	NOUN
biomedich-1001	59	8	using	use	VERB
biomedich-1001	59	9	an	an	DET
biomedich-1001	59	10	npt	npt	PROPN
biomedich-1001	59	11	ensemble	ensemble	ADJ
biomedich-1001	59	12	(	(	PUNCT
biomedich-1001	59	13	zubair	zubair	PROPN
biomedich-1001	59	14	et	et	PROPN
biomedich-1001	59	15	al	al	PROPN
biomedich-1001	59	16	.	.	PROPN
biomedich-1001	59	17	,	,	PUNCT
biomedich-1001	59	18	2020	2020	NUM
biomedich-1001	59	19	)	)	PUNCT
biomedich-1001	59	20	.	.	PUNCT
biomedich-1001	60	1	the	the	DET
biomedich-1001	60	2	results	result	NOUN
biomedich-1001	60	3	http://www.ebj.ac.uk/pdbsum	http://www.ebj.ac.uk/pdbsum	VERB
biomedich-1001	60	4	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	60	5	et	et	PROPN
biomedich-1001	60	6	al	al	PROPN
biomedich-1001	60	7	.	.	PUNCT
biomedich-1001	61	1	–	–	PUNCT
biomedich-1001	61	2	molecular	molecular	ADJ
biomedich-1001	61	3	dynamic	dynamic	ADJ
biomedich-1001	61	4	study	study	NOUN
biomedich-1001	61	5	of	of	ADP
biomedich-1001	61	6	java	java	PROPN
biomedich-1001	61	7	cardamom	cardamom	PROPN
biomedich-1001	61	8	(	(	PUNCT
biomedich-1001	61	9	wurfbania	wurfbania	PROPN
biomedich-1001	61	10	compacta	compacta	PROPN
biomedich-1001	61	11	)	)	PUNCT
biomedich-1001	61	12	…	…	PUNCT
biomedich-1001	61	13	1249	1249	NUM
biomedich-1001	61	14	of	of	ADP
biomedich-1001	61	15	the	the	DET
biomedich-1001	61	16	simulation	simulation	NOUN
biomedich-1001	61	17	were	be	AUX
biomedich-1001	61	18	analyzed	analyze	VERB
biomedich-1001	61	19	using	use	VERB
biomedich-1001	61	20	rmsd	rmsd	NOUN
biomedich-1001	61	21	,	,	PUNCT
biomedich-1001	61	22	rmsf	rmsf	NOUN
biomedich-1001	61	23	,	,	PUNCT
biomedich-1001	61	24	and	and	CCONJ
biomedich-1001	61	25	protein	protein	NOUN
biomedich-1001	61	26	-	-	PUNCT
biomedich-1001	61	27	ligand	ligand	NOUN
biomedich-1001	61	28	residue	residue	NOUN
biomedich-1001	61	29	contact	contact	NOUN
biomedich-1001	61	30	plots	plot	NOUN
biomedich-1001	61	31	.	.	PUNCT
biomedich-1001	62	1	results	result	NOUN
biomedich-1001	62	2	and	and	CCONJ
biomedich-1001	62	3	discussion	discussion	NOUN
biomedich-1001	62	4	result	result	NOUN
biomedich-1001	62	5	of	of	ADP
biomedich-1001	62	6	receptor	receptor	NOUN
biomedich-1001	62	7	identification	identification	NOUN
biomedich-1001	62	8	in	in	ADP
biomedich-1001	62	9	this	this	DET
biomedich-1001	62	10	study	study	NOUN
biomedich-1001	62	11	,	,	PUNCT
biomedich-1001	62	12	a	a	DET
biomedich-1001	62	13	receptor	receptor	NOUN
biomedich-1001	62	14	with	with	ADP
biomedich-1001	62	15	the	the	DET
biomedich-1001	62	16	pdb	pdb	PROPN
biomedich-1001	62	17	code	code	NOUN
biomedich-1001	62	18	3nvw	3nvw	PROPN
biomedich-1001	62	19	was	be	AUX
biomedich-1001	62	20	used	use	VERB
biomedich-1001	62	21	,	,	PUNCT
biomedich-1001	62	22	which	which	PRON
biomedich-1001	62	23	was	be	AUX
biomedich-1001	62	24	downloaded	download	VERB
biomedich-1001	62	25	from	from	ADP
biomedich-1001	62	26	the	the	DET
biomedich-1001	62	27	web	web	NOUN
biomedich-1001	62	28	server	server	NOUN
biomedich-1001	62	29	https://www.rcsb.org	https://www.rcsb.org	NUM
biomedich-1001	62	30	,	,	PUNCT
biomedich-1001	62	31	because	because	SCONJ
biomedich-1001	62	32	this	this	DET
biomedich-1001	62	33	receptor	receptor	NOUN
biomedich-1001	62	34	has	have	VERB
biomedich-1001	62	35	a	a	DET
biomedich-1001	62	36	resolution	resolution	NOUN
biomedich-1001	62	37	value	value	NOUN
biomedich-1001	62	38	of	of	ADP
biomedich-1001	62	39	1.6	1.6	NUM
biomedich-1001	62	40	å	å	PROPN
biomedich-1001	62	41	and	and	CCONJ
biomedich-1001	62	42	has	have	VERB
biomedich-1001	62	43	a	a	DET
biomedich-1001	62	44	natural	natural	ADJ
biomedich-1001	62	45	ligand	ligand	ADJ
biomedich-1001	62	46	structure	structure	NOUN
biomedich-1001	62	47	similar	similar	ADJ
biomedich-1001	62	48	to	to	ADP
biomedich-1001	62	49	the	the	DET
biomedich-1001	62	50	comparator	comparator	NOUN
biomedich-1001	62	51	drug	drug	NOUN
biomedich-1001	62	52	.	.	PUNCT
biomedich-1001	63	1	the	the	DET
biomedich-1001	63	2	receptor	receptor	NOUN
biomedich-1001	63	3	with	with	ADP
biomedich-1001	63	4	pdb	pdb	PROPN
biomedich-1001	63	5	code	code	PROPN
biomedich-1001	63	6	3nvw	3nvw	PROPN
biomedich-1001	63	7	has	have	VERB
biomedich-1001	63	8	a	a	DET
biomedich-1001	63	9	value	value	NOUN
biomedich-1001	63	10	of	of	ADP
biomedich-1001	63	11	most	most	ADV
biomedich-1001	63	12	favored	favor	VERB
biomedich-1001	63	13	regions	region	NOUN
biomedich-1001	63	14	of	of	ADP
biomedich-1001	63	15	90.0	90.0	NUM
biomedich-1001	63	16	%	%	NOUN
biomedich-1001	63	17	and	and	CCONJ
biomedich-1001	63	18	a	a	DET
biomedich-1001	63	19	value	value	NOUN
biomedich-1001	63	20	of	of	ADP
biomedich-1001	63	21	disallowed	disallow	VERB
biomedich-1001	63	22	regions	region	NOUN
biomedich-1001	63	23	of	of	ADP
biomedich-1001	63	24	0.2	0.2	NUM
biomedich-1001	63	25	%	%	NOUN
biomedich-1001	63	26	,	,	PUNCT
biomedich-1001	63	27	which	which	PRON
biomedich-1001	63	28	means	mean	VERB
biomedich-1001	63	29	it	it	PRON
biomedich-1001	63	30	meets	meet	VERB
biomedich-1001	63	31	the	the	DET
biomedich-1001	63	32	criteria	criterion	NOUN
biomedich-1001	63	33	and	and	CCONJ
biomedich-1001	63	34	can	can	AUX
biomedich-1001	63	35	be	be	AUX
biomedich-1001	63	36	used	use	VERB
biomedich-1001	63	37	as	as	ADP
biomedich-1001	63	38	a	a	DET
biomedich-1001	63	39	target	target	NOUN
biomedich-1001	63	40	protein	protein	NOUN
biomedich-1001	63	41	for	for	ADP
biomedich-1001	63	42	the	the	DET
biomedich-1001	63	43	binding	binding	NOUN
biomedich-1001	63	44	of	of	ADP
biomedich-1001	63	45	molecules	molecule	NOUN
biomedich-1001	63	46	against	against	ADP
biomedich-1001	63	47	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	63	48	activity	activity	NOUN
biomedich-1001	63	49	.	.	PUNCT
biomedich-1001	64	1	the	the	DET
biomedich-1001	64	2	receptor	receptor	NOUN
biomedich-1001	64	3	with	with	ADP
biomedich-1001	64	4	pdb	pdb	PROPN
biomedich-1001	64	5	code	code	PROPN
biomedich-1001	64	6	3nvw	3nvw	PROPN
biomedich-1001	64	7	has	have	VERB
biomedich-1001	64	8	an	an	DET
biomedich-1001	64	9	active	active	ADJ
biomedich-1001	64	10	site	site	NOUN
biomedich-1001	64	11	of	of	ADP
biomedich-1001	64	12	hydrogen	hydrogen	NOUN
biomedich-1001	64	13	bonds	bond	NOUN
biomedich-1001	64	14	with	with	ADP
biomedich-1001	64	15	amino	amino	ADJ
biomedich-1001	64	16	acids	acid	NOUN
biomedich-1001	64	17	namely	namely	ADV
biomedich-1001	64	18	glu802	glu802	ADJ
biomedich-1001	64	19	,	,	PUNCT
biomedich-1001	64	20	arg880	arg880	ADJ
biomedich-1001	64	21	,	,	PUNCT
biomedich-1001	64	22	thr1010	thr1010	NOUN
biomedich-1001	64	23	,	,	PUNCT
biomedich-1001	64	24	and	and	CCONJ
biomedich-1001	64	25	mos1328	mos1328	NOUN
biomedich-1001	64	26	.	.	PUNCT
biomedich-1001	65	1	meanwhile	meanwhile	ADV
biomedich-1001	65	2	,	,	PUNCT
biomedich-1001	65	3	for	for	SCONJ
biomedich-1001	65	4	the	the	DET
biomedich-1001	65	5	hydrophobic	hydrophobic	NOUN
biomedich-1001	65	6	binding	bind	VERB
biomedich-1001	65	7	interactions	interaction	NOUN
biomedich-1001	65	8	with	with	ADP
biomedich-1001	65	9	amino	amino	ADJ
biomedich-1001	65	10	acids	acid	NOUN
biomedich-1001	65	11	namely	namely	ADV
biomedich-1001	65	12	leu873	leu873	PROPN
biomedich-1001	65	13	,	,	PUNCT
biomedich-1001	65	14	ser876	ser876	NOUN
biomedich-1001	65	15	,	,	PUNCT
biomedich-1001	65	16	phe914	phe914	PROPN
biomedich-1001	65	17	,	,	PUNCT
biomedich-1001	65	18	phe1009	phe1009	NOUN
biomedich-1001	65	19	,	,	PUNCT
biomedich-1001	65	20	val1011	val1011	NOUN
biomedich-1001	65	21	,	,	PUNCT
biomedich-1001	65	22	leu1014	leu1014	NOUN
biomedich-1001	65	23	,	,	PUNCT
biomedich-1001	65	24	ala1078	ala1078	ADJ
biomedich-1001	65	25	,	,	PUNCT
biomedich-1001	65	26	and	and	CCONJ
biomedich-1001	65	27	ala1079	ala1079	NOUN
biomedich-1001	65	28	.	.	PUNCT
biomedich-1001	66	1	more	more	ADV
biomedich-1001	66	2	clear	clear	ADJ
biomedich-1001	66	3	interactions	interaction	NOUN
biomedich-1001	66	4	can	can	AUX
biomedich-1001	66	5	be	be	AUX
biomedich-1001	66	6	seen	see	VERB
biomedich-1001	66	7	in	in	ADP
biomedich-1001	66	8	figure	figure	NOUN
biomedich-1001	66	9	1	1	NUM
biomedich-1001	66	10	.	.	PUNCT
biomedich-1001	66	11	figure	figure	NOUN
biomedich-1001	66	12	2	2	NUM
biomedich-1001	66	13	.	.	PUNCT
biomedich-1001	66	14	active	active	ADJ
biomedich-1001	66	15	side	side	NOUN
biomedich-1001	66	16	of	of	ADP
biomedich-1001	66	17	xanthine	xanthine	NOUN
biomedich-1001	66	18	oxidase	oxidase	NOUN
biomedich-1001	66	19	receptor	receptor	NOUN
biomedich-1001	66	20	.	.	PUNCT
biomedich-1001	67	1	result	result	NOUN
biomedich-1001	67	2	of	of	ADP
biomedich-1001	67	3	docking	dock	VERB
biomedich-1001	67	4	validation	validation	NOUN
biomedich-1001	67	5	docking	docking	NOUN
biomedich-1001	67	6	validation	validation	NOUN
biomedich-1001	67	7	is	be	AUX
biomedich-1001	67	8	performed	perform	VERB
biomedich-1001	67	9	using	use	VERB
biomedich-1001	67	10	the	the	DET
biomedich-1001	67	11	autodocktools	autodocktools	NOUN
biomedich-1001	67	12	application	application	NOUN
biomedich-1001	67	13	,	,	PUNCT
biomedich-1001	67	14	by	by	ADP
biomedich-1001	67	15	re	re	VERB
biomedich-1001	67	16	-	-	VERB
biomedich-1001	67	17	docking	dock	VERB
biomedich-1001	67	18	the	the	DET
biomedich-1001	67	19	natural	natural	ADJ
biomedich-1001	67	20	ligand	ligand	NOUN
biomedich-1001	67	21	with	with	ADP
biomedich-1001	67	22	the	the	DET
biomedich-1001	67	23	prepared	prepared	ADJ
biomedich-1001	67	24	receptor	receptor	NOUN
biomedich-1001	67	25	.	.	PUNCT
biomedich-1001	68	1	the	the	DET
biomedich-1001	68	2	purpose	purpose	NOUN
biomedich-1001	68	3	of	of	ADP
biomedich-1001	68	4	this	this	DET
biomedich-1001	68	5	validation	validation	NOUN
biomedich-1001	68	6	is	be	AUX
biomedich-1001	68	7	to	to	PART
biomedich-1001	68	8	obtain	obtain	VERB
biomedich-1001	68	9	a	a	DET
biomedich-1001	68	10	valid	valid	ADJ
biomedich-1001	68	11	method	method	NOUN
biomedich-1001	68	12	,	,	PUNCT
biomedich-1001	68	13	which	which	PRON
biomedich-1001	68	14	is	be	AUX
biomedich-1001	68	15	said	say	VERB
biomedich-1001	68	16	to	to	PART
biomedich-1001	68	17	be	be	AUX
biomedich-1001	68	18	valid	valid	ADJ
biomedich-1001	68	19	if	if	SCONJ
biomedich-1001	68	20	the	the	DET
biomedich-1001	68	21	receptor	receptor	NOUN
biomedich-1001	68	22	has	have	VERB
biomedich-1001	68	23	an	an	DET
biomedich-1001	68	24	rmsd	rmsd	ADJ
biomedich-1001	68	25	value	value	NOUN
biomedich-1001	68	26	<	<	X
biomedich-1001	68	27	2	2	NUM
biomedich-1001	68	28	å	å	NOUN
biomedich-1001	68	29	.	.	PUNCT
biomedich-1001	69	1	this	this	PRON
biomedich-1001	69	2	is	be	AUX
biomedich-1001	69	3	because	because	SCONJ
biomedich-1001	69	4	the	the	PRON
biomedich-1001	69	5	smaller	small	ADJ
biomedich-1001	69	6	the	the	DET
biomedich-1001	69	7	rmsd	rmsd	NOUN
biomedich-1001	69	8	value	value	NOUN
biomedich-1001	69	9	,	,	PUNCT
biomedich-1001	69	10	the	the	PRON
biomedich-1001	69	11	more	more	ADV
biomedich-1001	69	12	similar	similar	ADJ
biomedich-1001	69	13	the	the	DET
biomedich-1001	69	14	position	position	NOUN
biomedich-1001	69	15	of	of	ADP
biomedich-1001	69	16	the	the	DET
biomedich-1001	69	17	docked	dock	VERB
biomedich-1001	69	18	natural	natural	ADJ
biomedich-1001	69	19	ligand	ligand	NOUN
biomedich-1001	69	20	is	be	AUX
biomedich-1001	69	21	to	to	ADP
biomedich-1001	69	22	that	that	PRON
biomedich-1001	69	23	of	of	ADP
biomedich-1001	69	24	the	the	DET
biomedich-1001	69	25	natural	natural	ADJ
biomedich-1001	69	26	crystallographic	crystallographic	ADJ
biomedich-1001	69	27	ligand	ligand	NOUN
biomedich-1001	69	28	.	.	PUNCT
biomedich-1001	70	1	based	base	VERB
biomedich-1001	70	2	on	on	ADP
biomedich-1001	70	3	the	the	DET
biomedich-1001	70	4	docking	docking	NOUN
biomedich-1001	70	5	validation	validation	NOUN
biomedich-1001	70	6	results	result	NOUN
biomedich-1001	70	7	in	in	ADP
biomedich-1001	70	8	table	table	NOUN
biomedich-1001	70	9	1	1	NUM
biomedich-1001	70	10	,	,	PUNCT
biomedich-1001	70	11	the	the	DET
biomedich-1001	70	12	receptor	receptor	NOUN
biomedich-1001	70	13	3nvw	3nvw	ADV
biomedich-1001	70	14	is	be	AUX
biomedich-1001	70	15	considered	consider	VERB
biomedich-1001	70	16	valid	valid	ADJ
biomedich-1001	70	17	because	because	SCONJ
biomedich-1001	70	18	the	the	DET
biomedich-1001	70	19	obtained	obtain	VERB
biomedich-1001	70	20	rmsd	rmsd	NOUN
biomedich-1001	70	21	value	value	NOUN
biomedich-1001	70	22	is	be	AUX
biomedich-1001	70	23	<	<	X
biomedich-1001	70	24	2	2	NUM
biomedich-1001	70	25	å	å	PROPN
biomedich-1001	70	26	,	,	PUNCT
biomedich-1001	70	27	which	which	PRON
biomedich-1001	70	28	is	be	AUX
biomedich-1001	70	29	0.27	0.27	NUM
biomedich-1001	70	30	å	å	NOUN
biomedich-1001	70	31	,	,	PUNCT
biomedich-1001	70	32	with	with	ADP
biomedich-1001	70	33	a	a	DET
biomedich-1001	70	34	binding	bind	VERB
biomedich-1001	70	35	energy	energy	NOUN
biomedich-1001	70	36	of	of	ADP
biomedich-1001	70	37	-6.88	-6.88	NUM
biomedich-1001	70	38	kkal	kkal	PROPN
biomedich-1001	70	39	/	/	SYM
biomedich-1001	70	40	mol	mol	NOUN
biomedich-1001	70	41	,	,	PUNCT
biomedich-1001	70	42	and	and	CCONJ
biomedich-1001	70	43	in	in	ADP
biomedich-1001	70	44	the	the	DET
biomedich-1001	70	45	gridbox	gridbox	NOUN
biomedich-1001	70	46	setup	setup	NOUN
biomedich-1001	70	47	,	,	PUNCT
biomedich-1001	70	48	x	x	X
biomedich-1001	70	49	=	=	SYM
biomedich-1001	70	50	38.017	38.017	NUM
biomedich-1001	70	51	,	,	PUNCT
biomedich-1001	70	52	y	y	PROPN
biomedich-1001	70	53	=	=	SYM
biomedich-1001	70	54	20.172	20.172	NUM
biomedich-1001	70	55	,	,	PUNCT
biomedich-1001	70	56	and	and	CCONJ
biomedich-1001	70	57	z	z	NOUN
biomedich-1001	70	58	=	=	SYM
biomedich-1001	70	59	18.698	18.698	NUM
biomedich-1001	70	60	.	.	PUNCT
biomedich-1001	71	1	the	the	DET
biomedich-1001	71	2	results	result	NOUN
biomedich-1001	71	3	from	from	ADP
biomedich-1001	71	4	redocking	redocking	NOUN
biomedich-1001	71	5	are	be	AUX
biomedich-1001	71	6	then	then	ADV
biomedich-1001	71	7	visualized	visualize	VERB
biomedich-1001	71	8	using	use	VERB
biomedich-1001	71	9	the	the	DET
biomedich-1001	71	10	biovia	biovia	PROPN
biomedich-1001	71	11	discovery	discovery	PROPN
biomedich-1001	71	12	studio	studio	PROPN
biomedich-1001	71	13	2017	2017	NUM
biomedich-1001	71	14	application	application	NOUN
biomedich-1001	71	15	to	to	PART
biomedich-1001	71	16	observe	observe	VERB
biomedich-1001	71	17	the	the	DET
biomedich-1001	71	18	interactions	interaction	NOUN
biomedich-1001	71	19	between	between	ADP
biomedich-1001	71	20	the	the	DET
biomedich-1001	71	21	ligand	ligand	NOUN
biomedich-1001	71	22	and	and	CCONJ
biomedich-1001	71	23	receptor	receptor	NOUN
biomedich-1001	71	24	,	,	PUNCT
biomedich-1001	71	25	allowing	allow	VERB
biomedich-1001	71	26	for	for	ADP
biomedich-1001	71	27	the	the	DET
biomedich-1001	71	28	identification	identification	NOUN
biomedich-1001	71	29	of	of	ADP
biomedich-1001	71	30	the	the	DET
biomedich-1001	71	31	interactions	interaction	NOUN
biomedich-1001	71	32	and	and	CCONJ
biomedich-1001	71	33	the	the	DET
biomedich-1001	71	34	amino	amino	NOUN
biomedich-1001	71	35	acid	acid	NOUN
biomedich-1001	71	36	residues	residue	NOUN
biomedich-1001	71	37	involved	involve	VERB
biomedich-1001	71	38	in	in	ADP
biomedich-1001	71	39	the	the	DET
biomedich-1001	71	40	ligand	ligand	ADJ
biomedich-1001	71	41	-	-	PUNCT
biomedich-1001	71	42	receptor	receptor	NOUN
biomedich-1001	71	43	complex	complex	NOUN
biomedich-1001	71	44	.	.	PUNCT
biomedich-1001	72	1	figure	figure	NOUN
biomedich-1001	72	2	3	3	NUM
biomedich-1001	72	3	.	.	PUNCT
biomedich-1001	72	4	2d	2d	NUM
biomedich-1001	72	5	visualization	visualization	NOUN
biomedich-1001	72	6	of	of	ADP
biomedich-1001	72	7	the	the	DET
biomedich-1001	72	8	redocking	redocking	NOUN
biomedich-1001	72	9	results	result	NOUN
biomedich-1001	72	10	of	of	ADP
biomedich-1001	72	11	receptor	receptor	NOUN
biomedich-1001	72	12	3nvw	3nvw	PROPN
biomedich-1001	72	13	.	.	PUNCT
biomedich-1001	73	1	figure	figure	NOUN
biomedich-1001	73	2	4	4	NUM
biomedich-1001	73	3	.	.	PUNCT
biomedich-1001	74	1	overlay	overlay	NOUN
biomedich-1001	74	2	results	result	NOUN
biomedich-1001	74	3	before	before	ADP
biomedich-1001	74	4	docking	docking	NOUN
biomedich-1001	74	5	(	(	PUNCT
biomedich-1001	74	6	red	red	ADJ
biomedich-1001	74	7	)	)	PUNCT
biomedich-1001	74	8	and	and	CCONJ
biomedich-1001	74	9	after	after	ADP
biomedich-1001	74	10	docking	docking	NOUN
biomedich-1001	74	11	(	(	PUNCT
biomedich-1001	74	12	teal	teal	NOUN
biomedich-1001	74	13	)	)	PUNCT
biomedich-1001	74	14	.	.	PUNCT
biomedich-1001	75	1	table	table	NOUN
biomedich-1001	75	2	1	1	NUM
biomedich-1001	75	3	.	.	PUNCT
biomedich-1001	76	1	docking	dock	VERB
biomedich-1001	76	2	validation	validation	NOUN
biomedich-1001	76	3	results	result	NOUN
biomedich-1001	76	4	.	.	PUNCT
biomedich-1001	77	1	pdb	pdb	PROPN
biomedich-1001	77	2	code	code	PROPN
biomedich-1001	77	3	grid	grid	PROPN
biomedich-1001	77	4	box	box	PROPN
biomedich-1001	77	5	rmsd	rmsd	NOUN
biomedich-1001	77	6	(	(	PUNCT
biomedich-1001	77	7	å	å	NOUN
biomedich-1001	77	8	)	)	PUNCT
biomedich-1001	77	9	binding	bind	VERB
biomedich-1001	77	10	energy	energy	NOUN
biomedich-1001	77	11	(	(	PUNCT
biomedich-1001	77	12	kkal	kkal	PROPN
biomedich-1001	77	13	/	/	SYM
biomedich-1001	77	14	mol	mol	NOUN
biomedich-1001	77	15	)	)	PUNCT
biomedich-1001	77	16	x	x	X
biomedich-1001	78	1	y	y	PROPN
biomedich-1001	78	2	z	z	PROPN
biomedich-1001	78	3	3nvw	3nvw	PROPN
biomedich-1001	78	4	38.017	38.017	NUM
biomedich-1001	78	5	20.172	20.172	NUM
biomedich-1001	78	6	18.698	18.698	NUM
biomedich-1001	78	7	0,27	0,27	NUM
biomedich-1001	78	8	-6.88	-6.88	NUM
biomedich-1001	78	9	result	result	NOUN
biomedich-1001	78	10	of	of	ADP
biomedich-1001	78	11	ligand	ligand	ADJ
biomedich-1001	78	12	preparation	preparation	NOUN
biomedich-1001	78	13	the	the	DET
biomedich-1001	78	14	test	test	NOUN
biomedich-1001	78	15	compound	compound	NOUN
biomedich-1001	78	16	from	from	ADP
biomedich-1001	78	17	cardamom	cardamom	NOUN
biomedich-1001	78	18	was	be	AUX
biomedich-1001	78	19	first	first	ADV
biomedich-1001	78	20	prepared	prepare	VERB
biomedich-1001	78	21	by	by	ADP
biomedich-1001	78	22	conducting	conduct	VERB
biomedich-1001	78	23	protonation	protonation	NOUN
biomedich-1001	78	24	and	and	CCONJ
biomedich-1001	78	25	conformational	conformational	ADJ
biomedich-1001	78	26	analysis	analysis	NOUN
biomedich-1001	78	27	using	use	VERB
biomedich-1001	78	28	the	the	DET
biomedich-1001	78	29	marvinsketch	marvinsketch	NOUN
biomedich-1001	78	30	application	application	NOUN
biomedich-1001	78	31	.	.	PUNCT
biomedich-1001	79	1	the	the	DET
biomedich-1001	79	2	compounds	compound	NOUN
biomedich-1001	79	3	prepared	prepare	VERB
biomedich-1001	79	4	included	include	VERB
biomedich-1001	79	5	15	15	NUM
biomedich-1001	79	6	compounds	compound	NOUN
biomedich-1001	79	7	such	such	ADJ
biomedich-1001	79	8	as	as	ADP
biomedich-1001	79	9	5	5	NUM
biomedich-1001	79	10	-	-	PUNCT
biomedich-1001	79	11	hydroxy3,7,4'-trimethoxyflavone	hydroxy3,7,4'-trimethoxyflavone	NOUN
biomedich-1001	79	12	,	,	PUNCT
biomedich-1001	79	13	+	+	ADJ
biomedich-1001	79	14	/-.-2	/-.-2	PROPN
biomedich-1001	79	15	-	-	PUNCT
biomedich-1001	79	16	methoxy-3,8dioxocephalotax-1	methoxy-3,8dioxocephalotax-1	PROPN
biomedich-1001	79	17	-	-	PUNCT
biomedich-1001	79	18	ene	ene	NOUN
biomedich-1001	79	19	,	,	PUNCT
biomedich-1001	79	20	erucyl	erucyl	NOUN
biomedich-1001	79	21	amide	amide	NOUN
biomedich-1001	79	22	,	,	PUNCT
biomedich-1001	79	23	linolenic	linolenic	NOUN
biomedich-1001	79	24	acid	acid	NOUN
biomedich-1001	79	25	,	,	PUNCT
biomedich-1001	79	26	phytol	phytol	NOUN
biomedich-1001	79	27	,	,	PUNCT
biomedich-1001	79	28	hexadecanoic	hexadecanoic	ADJ
biomedich-1001	79	29	acid	acid	NOUN
biomedich-1001	79	30	,	,	PUNCT
biomedich-1001	79	31	neophytadiene	neophytadiene	NOUN
biomedich-1001	79	32	,	,	PUNCT
biomedich-1001	79	33	carvestrene	carvestrene	NOUN
biomedich-1001	79	34	,	,	PUNCT
biomedich-1001	79	35	carvol	carvol	NOUN
biomedich-1001	79	36	,	,	PUNCT
biomedich-1001	79	37	1,8	1,8	NOUN
biomedich-1001	79	38	-	-	PUNCT
biomedich-1001	79	39	cineole	cineole	NOUN
biomedich-1001	79	40	,	,	PUNCT
biomedich-1001	79	41	kaempferol	kaempferol	NOUN
biomedich-1001	79	42	,	,	PUNCT
biomedich-1001	79	43	quercetin	quercetin	NOUN
biomedich-1001	79	44	,	,	PUNCT
biomedich-1001	79	45	luteolin	luteolin	PROPN
biomedich-1001	79	46	,	,	PUNCT
biomedich-1001	79	47	pelargonidin	pelargonidin	NOUN
biomedich-1001	79	48	,	,	PUNCT
biomedich-1001	79	49	and	and	CCONJ
biomedich-1001	79	50	allopurinol	allopurinol	NOUN
biomedich-1001	79	51	.	.	PUNCT
biomedich-1001	80	1	the	the	DET
biomedich-1001	80	2	purpose	purpose	NOUN
biomedich-1001	80	3	of	of	ADP
biomedich-1001	80	4	the	the	DET
biomedich-1001	80	5	protonation	protonation	NOUN
biomedich-1001	80	6	stage	stage	NOUN
biomedich-1001	80	7	is	be	AUX
biomedich-1001	80	8	to	to	PART
biomedich-1001	80	9	adjust	adjust	VERB
biomedich-1001	80	10	the	the	DET
biomedich-1001	80	11	ph	ph	NOUN
biomedich-1001	80	12	of	of	ADP
biomedich-1001	80	13	the	the	DET
biomedich-1001	80	14	test	test	NOUN
biomedich-1001	80	15	compound	compound	NOUN
biomedich-1001	80	16	to	to	ADP
biomedich-1001	80	17	the	the	DET
biomedich-1001	80	18	physiological	physiological	ADJ
biomedich-1001	80	19	ph	ph	NOUN
biomedich-1001	80	20	of	of	ADP
biomedich-1001	80	21	the	the	DET
biomedich-1001	80	22	human	human	ADJ
biomedich-1001	80	23	body	body	NOUN
biomedich-1001	80	24	,	,	PUNCT
biomedich-1001	80	25	which	which	PRON
biomedich-1001	80	26	is	be	AUX
biomedich-1001	80	27	7.4	7.4	NUM
biomedich-1001	80	28	.	.	PUNCT
biomedich-1001	81	1	next	next	ADJ
biomedich-1001	81	2	,	,	PUNCT
biomedich-1001	81	3	the	the	DET
biomedich-1001	81	4	conformation	conformation	NOUN
biomedich-1001	81	5	is	be	AUX
biomedich-1001	81	6	performed	perform	VERB
biomedich-1001	81	7	to	to	PART
biomedich-1001	81	8	maintain	maintain	VERB
biomedich-1001	81	9	the	the	DET
biomedich-1001	81	10	position	position	NOUN
biomedich-1001	81	11	of	of	ADP
biomedich-1001	81	12	the	the	DET
biomedich-1001	81	13	molecule	molecule	NOUN
biomedich-1001	81	14	that	that	PRON
biomedich-1001	81	15	is	be	AUX
biomedich-1001	81	16	most	most	ADV
biomedich-1001	81	17	stable	stable	ADJ
biomedich-1001	81	18	when	when	SCONJ
biomedich-1001	81	19	interacting	interact	VERB
biomedich-1001	81	20	with	with	ADP
biomedich-1001	81	21	the	the	DET
biomedich-1001	81	22	active	active	ADJ
biomedich-1001	81	23	site	site	NOUN
biomedich-1001	81	24	of	of	ADP
biomedich-1001	81	25	the	the	DET
biomedich-1001	81	26	receptor	receptor	NOUN
biomedich-1001	81	27	.	.	PUNCT
biomedich-1001	82	1	1250	1250	NUM
biomedich-1001	82	2	biology	biology	NOUN
biomedich-1001	82	3	,	,	PUNCT
biomedich-1001	82	4	medicine	medicine	NOUN
biomedich-1001	82	5	,	,	PUNCT
biomedich-1001	82	6	&	&	CCONJ
biomedich-1001	82	7	natural	natural	ADJ
biomedich-1001	82	8	product	product	NOUN
biomedich-1001	82	9	chemistry	chemistry	NOUN
biomedich-1001	82	10	14	14	NUM
biomedich-1001	82	11	(	(	PUNCT
biomedich-1001	82	12	2	2	NUM
biomedich-1001	82	13	)	)	PUNCT
biomedich-1001	82	14	,	,	PUNCT
biomedich-1001	82	15	2025	2025	NUM
biomedich-1001	82	16	:	:	PUNCT
biomedich-1001	82	17	1247	1247	NUM
biomedich-1001	82	18	-	-	SYM
biomedich-1001	82	19	1256	1256	NUM
biomedich-1001	82	20	result	result	NOUN
biomedich-1001	82	21	of	of	ADP
biomedich-1001	82	22	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	82	23	and	and	CCONJ
biomedich-1001	82	24	toxicity	toxicity	NOUN
biomedich-1001	82	25	the	the	DET
biomedich-1001	82	26	parameters	parameter	NOUN
biomedich-1001	82	27	analyzed	analyze	VERB
biomedich-1001	82	28	include	include	VERB
biomedich-1001	82	29	the	the	DET
biomedich-1001	82	30	ames	ames	PROPN
biomedich-1001	82	31	test	test	NOUN
biomedich-1001	82	32	which	which	PRON
biomedich-1001	82	33	aims	aim	VERB
biomedich-1001	82	34	to	to	PART
biomedich-1001	82	35	demonstrate	demonstrate	VERB
biomedich-1001	82	36	the	the	DET
biomedich-1001	82	37	mutagenic	mutagenic	ADJ
biomedich-1001	82	38	potential	potential	NOUN
biomedich-1001	82	39	of	of	ADP
biomedich-1001	82	40	compounds	compound	NOUN
biomedich-1001	82	41	.	.	PUNCT
biomedich-1001	83	1	additionally	additionally	ADV
biomedich-1001	83	2	,	,	PUNCT
biomedich-1001	83	3	it	it	PRON
biomedich-1001	83	4	analyzes	analyze	VERB
biomedich-1001	83	5	oral	oral	ADJ
biomedich-1001	83	6	rat	rat	NOUN
biomedich-1001	83	7	acute	acute	NOUN
biomedich-1001	83	8	toxicity	toxicity	NOUN
biomedich-1001	83	9	(	(	PUNCT
biomedich-1001	83	10	ld50	ld50	PROPN
biomedich-1001	83	11	)	)	PUNCT
biomedich-1001	83	12	and	and	CCONJ
biomedich-1001	83	13	hepatotoxicity	hepatotoxicity	NOUN
biomedich-1001	83	14	.	.	PUNCT
biomedich-1001	84	1	the	the	DET
biomedich-1001	84	2	results	result	NOUN
biomedich-1001	84	3	of	of	ADP
biomedich-1001	84	4	the	the	DET
biomedich-1001	84	5	toxicity	toxicity	NOUN
biomedich-1001	84	6	tests	test	NOUN
biomedich-1001	84	7	can	can	AUX
biomedich-1001	84	8	be	be	AUX
biomedich-1001	84	9	seen	see	VERB
biomedich-1001	84	10	in	in	ADP
biomedich-1001	84	11	table	table	NOUN
biomedich-1001	84	12	2	2	NUM
biomedich-1001	84	13	.	.	PUNCT
biomedich-1001	85	1	furthermore	furthermore	ADV
biomedich-1001	85	2	,	,	PUNCT
biomedich-1001	85	3	9	9	NUM
biomedich-1001	85	4	test	test	NOUN
biomedich-1001	85	5	compounds	compound	NOUN
biomedich-1001	85	6	and	and	CCONJ
biomedich-1001	85	7	a	a	DET
biomedich-1001	85	8	comparator	comparator	NOUN
biomedich-1001	85	9	drug	drug	NOUN
biomedich-1001	85	10	that	that	PRON
biomedich-1001	85	11	passed	pass	VERB
biomedich-1001	85	12	the	the	DET
biomedich-1001	85	13	toxicity	toxicity	NOUN
biomedich-1001	85	14	test	test	NOUN
biomedich-1001	85	15	were	be	AUX
biomedich-1001	85	16	continued	continue	VERB
biomedich-1001	85	17	with	with	ADP
biomedich-1001	85	18	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	85	19	testing	testing	NOUN
biomedich-1001	85	20	.	.	PUNCT
biomedich-1001	86	1	table	table	NOUN
biomedich-1001	86	2	2	2	NUM
biomedich-1001	86	3	.	.	PUNCT
biomedich-1001	86	4	toxicity	toxicity	NOUN
biomedich-1001	86	5	and	and	CCONJ
biomedich-1001	86	6	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	86	7	test	test	NOUN
biomedich-1001	86	8	results	result	NOUN
biomedich-1001	86	9	.	.	PUNCT
biomedich-1001	87	1	no	no	DET
biomedich-1001	87	2	compounds	compound	NOUN
biomedich-1001	87	3	name	name	NOUN
biomedich-1001	87	4	toxicity	toxicity	NOUN
biomedich-1001	87	5	test	test	NOUN
biomedich-1001	87	6	phamacokinetic	phamacokinetic	ADJ
biomedich-1001	87	7	test	test	NOUN
biomedich-1001	87	8	ames	ame	NOUN
biomedich-1001	87	9	toxicity	toxicity	NOUN
biomedich-1001	87	10	ld50	ld50	PROPN
biomedich-1001	87	11	(	(	PUNCT
biomedich-1001	87	12	mol	mol	PROPN
biomedich-1001	87	13	/	/	SYM
biomedich-1001	87	14	kg	kg	PROPN
biomedich-1001	87	15	)	)	PUNCT
biomedich-1001	87	16	hepatotoxicity	hepatotoxicity	NOUN
biomedich-1001	87	17	caco-2	caco-2	NUM
biomedich-1001	87	18	hia	hia	PROPN
biomedich-1001	87	19	(	(	PUNCT
biomedich-1001	87	20	%	%	INTJ
biomedich-1001	87	21	)	)	PUNCT
biomedich-1001	87	22	ppb	ppb	NOUN
biomedich-1001	87	23	(	(	PUNCT
biomedich-1001	87	24	%	%	NOUN
biomedich-1001	87	25	)	)	PUNCT
biomedich-1001	87	26	1	1	NUM
biomedich-1001	87	27	5	5	NUM
biomedich-1001	87	28	-	-	PUNCT
biomedich-1001	87	29	hidroxy-3,7,4'-trimetoksiflavon	hidroxy-3,7,4'-trimetoksiflavon	NOUN
biomedich-1001	87	30	no	no	PRON
biomedich-1001	87	31	2.639	2.639	NUM
biomedich-1001	87	32	no	no	DET
biomedich-1001	87	33	23.67	23.67	NUM
biomedich-1001	87	34	96.48	96.48	NUM
biomedich-1001	87	35	82.47	82.47	NUM
biomedich-1001	87	36	2	2	NUM
biomedich-1001	87	37	2	2	NUM
biomedich-1001	87	38	-	-	PUNCT
biomedich-1001	87	39	methoxy-3,8	methoxy-3,8	NOUN
biomedich-1001	87	40	-	-	PUNCT
biomedich-1001	87	41	dioxocephalotax-1	dioxocephalotax-1	NOUN
biomedich-1001	87	42	-	-	PUNCT
biomedich-1001	87	43	ene	ene	NOUN
biomedich-1001	87	44	yes	yes	ADV
biomedich-1001	87	45	2.36	2.36	NUM
biomedich-1001	87	46	yes	yes	NOUN
biomedich-1001	87	47	3	3	NUM
biomedich-1001	87	48	erucyl	erucyl	NOUN
biomedich-1001	87	49	amide	amide	VERB
biomedich-1001	87	50	no	no	DET
biomedich-1001	87	51	1.863	1.863	NUM
biomedich-1001	87	52	no	no	DET
biomedich-1001	87	53	35.78	35.78	NUM
biomedich-1001	87	54	95.56	95.56	NUM
biomedich-1001	87	55	100	100	NUM
biomedich-1001	87	56	4	4	NUM
biomedich-1001	87	57	linolenic	linolenic	NOUN
biomedich-1001	87	58	acid	acid	NOUN
biomedich-1001	87	59	no	no	DET
biomedich-1001	87	60	1.624	1.624	NUM
biomedich-1001	87	61	yes	yes	NOUN
biomedich-1001	87	62	5	5	NUM
biomedich-1001	87	63	phytol	phytol	NOUN
biomedich-1001	87	64	no	no	DET
biomedich-1001	87	65	1.546	1.546	NUM
biomedich-1001	87	66	no	no	PROPN
biomedich-1001	87	67	37.62	37.62	NUM
biomedich-1001	87	68	100	100	NUM
biomedich-1001	87	69	100	100	NUM
biomedich-1001	87	70	6	6	NUM
biomedich-1001	87	71	hexadenoic	hexadenoic	ADJ
biomedich-1001	87	72	acid	acid	NOUN
biomedich-1001	87	73	no	no	DET
biomedich-1001	87	74	1.595	1.595	NUM
biomedich-1001	87	75	no	no	DET
biomedich-1001	87	76	27.52	27.52	NUM
biomedich-1001	87	77	98.29	98.29	NUM
biomedich-1001	87	78	100	100	NUM
biomedich-1001	87	79	7	7	NUM
biomedich-1001	87	80	neophytadiene	neophytadiene	NOUN
biomedich-1001	87	81	no	no	DET
biomedich-1001	87	82	1.48	1.48	NUM
biomedich-1001	87	83	no	no	DET
biomedich-1001	87	84	23.15	23.15	NUM
biomedich-1001	87	85	100	100	NUM
biomedich-1001	87	86	100	100	NUM
biomedich-1001	87	87	8	8	NUM
biomedich-1001	87	88	carvestrene	carvestrene	NOUN
biomedich-1001	87	89	no	no	DET
biomedich-1001	87	90	1.847	1.847	NUM
biomedich-1001	87	91	no	no	DET
biomedich-1001	87	92	23.63	23.63	NUM
biomedich-1001	87	93	100	100	NUM
biomedich-1001	87	94	100	100	NUM
biomedich-1001	87	95	9	9	NUM
biomedich-1001	87	96	carvol	carvol	NOUN
biomedich-1001	87	97	no	no	DET
biomedich-1001	87	98	1.781	1.781	NUM
biomedich-1001	87	99	no	no	DET
biomedich-1001	87	100	47.74	47.74	NUM
biomedich-1001	87	101	100	100	NUM
biomedich-1001	87	102	58.04	58.04	NUM
biomedich-1001	87	103	10	10	NUM
biomedich-1001	87	104	1,8	1,8	NUM
biomedich-1001	87	105	-	-	PUNCT
biomedich-1001	87	106	cineole	cineole	NOUN
biomedich-1001	88	1	no	no	DET
biomedich-1001	88	2	2.013	2.013	NUM
biomedich-1001	88	3	no	no	DET
biomedich-1001	88	4	21.89	21.89	NUM
biomedich-1001	88	5	100	100	NUM
biomedich-1001	88	6	100	100	NUM
biomedich-1001	88	7	11	11	NUM
biomedich-1001	88	8	kaempferol	kaempferol	NOUN
biomedich-1001	88	9	no	no	DET
biomedich-1001	88	10	2.317	2.317	NUM
biomedich-1001	88	11	no	no	DET
biomedich-1001	88	12	9.49	9.49	NUM
biomedich-1001	88	13	83.92	83.92	NUM
biomedich-1001	88	14	79.38	79.38	NUM
biomedich-1001	88	15	12	12	NUM
biomedich-1001	88	16	quercetin	quercetin	NOUN
biomedich-1001	88	17	yes	yes	NOUN
biomedich-1001	88	18	2.551	2.551	NUM
biomedich-1001	88	19	no	no	DET
biomedich-1001	88	20	13	13	NUM
biomedich-1001	88	21	luteolin	luteolin	INTJ
biomedich-1001	89	1	yes	yes	INTJ
biomedich-1001	89	2	2.709	2.709	NUM
biomedich-1001	90	1	no	no	DET
biomedich-1001	90	2	14	14	NUM
biomedich-1001	90	3	pelargonidin	pelargonidin	VERB
biomedich-1001	90	4	yes	yes	INTJ
biomedich-1001	90	5	2.38	2.38	NUM
biomedich-1001	90	6	no	no	DET
biomedich-1001	90	7	15	15	NUM
biomedich-1001	90	8	allopurinol	allopurinol	NOUN
biomedich-1001	90	9	no	no	DET
biomedich-1001	90	10	2.424	2.424	NUM
biomedich-1001	90	11	no	no	DET
biomedich-1001	90	12	16,52	16,52	NUM
biomedich-1001	90	13	78,26	78,26	NOUN
biomedich-1001	90	14	3,11	3,11	NUM
biomedich-1001	90	15	description	description	NOUN
biomedich-1001	90	16	:	:	PUNCT
biomedich-1001	90	17	:	:	PUNCT
biomedich-1001	90	18	not	not	PART
biomedich-1001	90	19	qualified	qualified	ADJ
biomedich-1001	90	20	:	:	PUNCT
biomedich-1001	90	21	qualified	qualified	ADJ
biomedich-1001	90	22	caco-2	caco-2	NOUN
biomedich-1001	90	23	:	:	PUNCT
biomedich-1001	90	24	<	<	X
biomedich-1001	90	25	4	4	NUM
biomedich-1001	90	26	low	low	ADJ
biomedich-1001	90	27	permeability	permeability	NOUN
biomedich-1001	90	28	,	,	PUNCT
biomedich-1001	90	29	4	4	NUM
biomedich-1001	90	30	-	-	SYM
biomedich-1001	90	31	70	70	NUM
biomedich-1001	90	32	moderate	moderate	ADJ
biomedich-1001	90	33	permeability	permeability	NOUN
biomedich-1001	90	34	,	,	PUNCT
biomedich-1001	90	35	>	>	X
biomedich-1001	90	36	70	70	NUM
biomedich-1001	90	37	high	high	ADJ
biomedich-1001	90	38	permeability	permeability	NOUN
biomedich-1001	90	39	.	.	PUNCT
biomedich-1001	91	1	hia	hia	PROPN
biomedich-1001	91	2	:	:	PUNCT
biomedich-1001	91	3	0	0	NUM
biomedich-1001	91	4	-	-	SYM
biomedich-1001	91	5	20	20	NUM
biomedich-1001	91	6	%	%	NOUN
biomedich-1001	91	7	low	low	ADJ
biomedich-1001	91	8	absorption	absorption	NOUN
biomedich-1001	91	9	,	,	PUNCT
biomedich-1001	91	10	2070	2070	NUM
biomedich-1001	91	11	%	%	NOUN
biomedich-1001	91	12	moderate	moderate	ADJ
biomedich-1001	91	13	absorption	absorption	NOUN
biomedich-1001	91	14	,	,	PUNCT
biomedich-1001	91	15	70	70	NUM
biomedich-1001	91	16	-	-	SYM
biomedich-1001	91	17	100	100	NUM
biomedich-1001	91	18	%	%	NOUN
biomedich-1001	91	19	high	high	ADJ
biomedich-1001	91	20	absorption	absorption	NOUN
biomedich-1001	91	21	.	.	PUNCT
biomedich-1001	92	1	ppb	ppb	VERB
biomedich-1001	92	2	<	<	X
biomedich-1001	93	1	90	90	NUM
biomedich-1001	93	2	%	%	NOUN
biomedich-1001	93	3	weak	weak	ADJ
biomedich-1001	93	4	binding	binding	NOUN
biomedich-1001	93	5	,	,	PUNCT
biomedich-1001	93	6	>	>	X
biomedich-1001	93	7	90	90	NUM
biomedich-1001	93	8	%	%	NOUN
biomedich-1001	93	9	strong	strong	ADJ
biomedich-1001	93	10	binding	bind	VERB
biomedich-1001	93	11	.	.	PUNCT
biomedich-1001	94	1	result	result	NOUN
biomedich-1001	94	2	of	of	ADP
biomedich-1001	94	3	drug	drug	NOUN
biomedich-1001	94	4	scan	scan	PROPN
biomedich-1001	94	5	drug	drug	PROPN
biomedich-1001	94	6	scan	scan	PROPN
biomedich-1001	94	7	was	be	AUX
biomedich-1001	94	8	performed	perform	VERB
biomedich-1001	94	9	using	use	VERB
biomedich-1001	94	10	the	the	DET
biomedich-1001	94	11	lipinski	lipinski	PROPN
biomedich-1001	94	12	’s	’s	PART
biomedich-1001	94	13	program	program	NOUN
biomedich-1001	94	14	to	to	PART
biomedich-1001	94	15	analyze	analyze	VERB
biomedich-1001	94	16	the	the	DET
biomedich-1001	94	17	physicochemical	physicochemical	ADJ
biomedich-1001	94	18	properties	property	NOUN
biomedich-1001	94	19	of	of	ADP
biomedich-1001	94	20	cardamom	cardamom	NOUN
biomedich-1001	94	21	.	.	PUNCT
biomedich-1001	95	1	the	the	DET
biomedich-1001	95	2	physicochemical	physicochemical	ADJ
biomedich-1001	95	3	properties	property	NOUN
biomedich-1001	95	4	are	be	AUX
biomedich-1001	95	5	analyzed	analyze	VERB
biomedich-1001	95	6	to	to	PART
biomedich-1001	95	7	observe	observe	VERB
biomedich-1001	95	8	the	the	DET
biomedich-1001	95	9	similarity	similarity	NOUN
biomedich-1001	95	10	of	of	ADP
biomedich-1001	95	11	a	a	DET
biomedich-1001	95	12	compound	compound	NOUN
biomedich-1001	95	13	to	to	ADP
biomedich-1001	95	14	oral	oral	ADJ
biomedich-1001	95	15	drugs	drug	NOUN
biomedich-1001	95	16	through	through	ADP
biomedich-1001	95	17	the	the	DET
biomedich-1001	95	18	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	95	19	processes	process	NOUN
biomedich-1001	95	20	that	that	PRON
biomedich-1001	95	21	occur	occur	VERB
biomedich-1001	95	22	in	in	ADP
biomedich-1001	95	23	the	the	DET
biomedich-1001	95	24	body	body	NOUN
biomedich-1001	95	25	.	.	PUNCT
biomedich-1001	96	1	a	a	DET
biomedich-1001	96	2	compound	compound	NOUN
biomedich-1001	96	3	is	be	AUX
biomedich-1001	96	4	considered	consider	VERB
biomedich-1001	96	5	good	good	ADJ
biomedich-1001	96	6	if	if	SCONJ
biomedich-1001	96	7	it	it	PRON
biomedich-1001	96	8	meets	meet	VERB
biomedich-1001	96	9	2	2	NUM
biomedich-1001	96	10	or	or	CCONJ
biomedich-1001	96	11	more	more	ADJ
biomedich-1001	96	12	criteria	criterion	NOUN
biomedich-1001	96	13	of	of	ADP
biomedich-1001	96	14	the	the	DET
biomedich-1001	96	15	lipinski	lipinski	PROPN
biomedich-1001	96	16	’s	’s	PART
biomedich-1001	96	17	rule	rule	NOUN
biomedich-1001	96	18	,	,	PUNCT
biomedich-1001	96	19	which	which	PRON
biomedich-1001	96	20	are	be	AUX
biomedich-1001	96	21	molecular	molecular	ADJ
biomedich-1001	96	22	weight	weight	NOUN
biomedich-1001	96	23	<	<	X
biomedich-1001	96	24	500g	500g	PROPN
biomedich-1001	96	25	/	/	SYM
biomedich-1001	96	26	mol	mol	PROPN
biomedich-1001	96	27	,	,	PUNCT
biomedich-1001	96	28	log	log	VERB
biomedich-1001	96	29	p	p	NOUN
biomedich-1001	96	30	<	<	X
biomedich-1001	96	31	5	5	NUM
biomedich-1001	96	32	,	,	PUNCT
biomedich-1001	96	33	hydrogen	hydrogen	NOUN
biomedich-1001	96	34	bond	bond	NOUN
biomedich-1001	96	35	donors	donor	NOUN
biomedich-1001	96	36	<	<	X
biomedich-1001	96	37	5	5	NUM
biomedich-1001	96	38	,	,	PUNCT
biomedich-1001	96	39	hydrogen	hydrogen	NOUN
biomedich-1001	96	40	bond	bond	NOUN
biomedich-1001	96	41	acceptors	acceptor	NOUN
biomedich-1001	96	42	<	<	X
biomedich-1001	96	43	10	10	NUM
biomedich-1001	96	44	,	,	PUNCT
biomedich-1001	96	45	and	and	CCONJ
biomedich-1001	96	46	molar	molar	ADJ
biomedich-1001	96	47	refractivity	refractivity	NOUN
biomedich-1001	96	48	between	between	ADP
biomedich-1001	96	49	40	40	NUM
biomedich-1001	96	50	-	-	SYM
biomedich-1001	96	51	130	130	NUM
biomedich-1001	96	52	(	(	PUNCT
biomedich-1001	96	53	yusuf	yusuf	PROPN
biomedich-1001	96	54	et	et	PROPN
biomedich-1001	96	55	al	al	PROPN
biomedich-1001	96	56	.	.	PROPN
biomedich-1001	96	57	,	,	PUNCT
biomedich-1001	96	58	2022	2022	NUM
biomedich-1001	96	59	)	)	PUNCT
biomedich-1001	96	60	.	.	PUNCT
biomedich-1001	97	1	table	table	NOUN
biomedich-1001	97	2	3	3	NUM
biomedich-1001	97	3	.	.	X
biomedich-1001	97	4	drug	drug	NOUN
biomedich-1001	97	5	scan	scan	PROPN
biomedich-1001	97	6	results	result	NOUN
biomedich-1001	97	7	.	.	PUNCT
biomedich-1001	98	1	no	no	DET
biomedich-1001	98	2	compounds	compound	NOUN
biomedich-1001	98	3	name	name	VERB
biomedich-1001	98	4	molecular	molecular	ADJ
biomedich-1001	98	5	weight	weight	NOUN
biomedich-1001	98	6	(	(	PUNCT
biomedich-1001	98	7	g	g	NOUN
biomedich-1001	98	8	/	/	SYM
biomedich-1001	98	9	mol	mol	NOUN
biomedich-1001	98	10	)	)	PUNCT
biomedich-1001	98	11	log	log	NOUN
biomedich-1001	98	12	p	p	NOUN
biomedich-1001	98	13	hydrogen	hydrogen	NOUN
biomedich-1001	98	14	bond	bond	NOUN
biomedich-1001	98	15	donor	donor	NOUN
biomedich-1001	98	16	hydrogen	hydrogen	NOUN
biomedich-1001	98	17	bond	bond	NOUN
biomedich-1001	98	18	acceptor	acceptor	NOUN
biomedich-1001	98	19	molar	molar	ADJ
biomedich-1001	98	20	refractory	refractory	NOUN
biomedich-1001	98	21	1	1	NUM
biomedich-1001	98	22	5	5	NUM
biomedich-1001	98	23	-	-	NUM
biomedich-1001	98	24	hidroksi-3,7,4'-trimetoksiflavon	hidroksi-3,7,4'-trimetoksiflavon	PROPN
biomedich-1001	98	25	328	328	NUM
biomedich-1001	98	26	2,9	2,9	NUM
biomedich-1001	98	27	1	1	NUM
biomedich-1001	98	28	6	6	NUM
biomedich-1001	98	29	86,5	86,5	NUM
biomedich-1001	98	30	2	2	NUM
biomedich-1001	98	31	carvol	carvol	NOUN
biomedich-1001	98	32	150	150	NUM
biomedich-1001	98	33	2,48	2,48	NUM
biomedich-1001	98	34	0	0	NUM
biomedich-1001	98	35	1	1	NUM
biomedich-1001	98	36	46,3	46,3	NUM
biomedich-1001	98	37	3	3	NUM
biomedich-1001	98	38	kaempferol	kaempferol	NOUN
biomedich-1001	98	39	285	285	NUM
biomedich-1001	98	40	0,75	0,75	NUM
biomedich-1001	98	41	3	3	NUM
biomedich-1001	98	42	6	6	NUM
biomedich-1001	98	43	70,87	70,87	NUM
biomedich-1001	98	44	4	4	NUM
biomedich-1001	98	45	allopurinol	allopurinol	NOUN
biomedich-1001	98	46	136	136	NUM
biomedich-1001	98	47	0,05	0,05	NOUN
biomedich-1001	98	48	2	2	NUM
biomedich-1001	98	49	4	4	NUM
biomedich-1001	98	50	33,34	33,34	NUM
biomedich-1001	98	51	result	result	NOUN
biomedich-1001	98	52	of	of	ADP
biomedich-1001	98	53	molecular	molecular	ADJ
biomedich-1001	98	54	docking	docking	NOUN
biomedich-1001	98	55	and	and	CCONJ
biomedich-1001	98	56	visualization	visualization	NOUN
biomedich-1001	98	57	based	base	VERB
biomedich-1001	98	58	on	on	ADP
biomedich-1001	98	59	the	the	DET
biomedich-1001	98	60	docking	docking	NOUN
biomedich-1001	98	61	results	result	NOUN
biomedich-1001	98	62	in	in	ADP
biomedich-1001	98	63	table	table	NOUN
biomedich-1001	98	64	4	4	NUM
biomedich-1001	98	65	,	,	PUNCT
biomedich-1001	98	66	it	it	PRON
biomedich-1001	98	67	can	can	AUX
biomedich-1001	98	68	be	be	AUX
biomedich-1001	98	69	seen	see	VERB
biomedich-1001	98	70	that	that	SCONJ
biomedich-1001	98	71	there	there	PRON
biomedich-1001	98	72	are	be	VERB
biomedich-1001	98	73	several	several	ADJ
biomedich-1001	98	74	compounds	compound	NOUN
biomedich-1001	98	75	with	with	ADP
biomedich-1001	98	76	lower	low	ADJ
biomedich-1001	98	77	binding	bind	VERB
biomedich-1001	98	78	energy	energy	NOUN
biomedich-1001	98	79	(	(	PUNCT
biomedich-1001	98	80	δg	δg	NOUN
biomedich-1001	98	81	)	)	PUNCT
biomedich-1001	98	82	and	and	CCONJ
biomedich-1001	98	83	inhibition	inhibition	VERB
biomedich-1001	98	84	constant	constant	ADJ
biomedich-1001	98	85	(	(	PUNCT
biomedich-1001	98	86	ki	ki	INTJ
biomedich-1001	98	87	)	)	PUNCT
biomedich-1001	98	88	values	value	NOUN
biomedich-1001	98	89	compared	compare	VERB
biomedich-1001	98	90	to	to	ADP
biomedich-1001	98	91	the	the	DET
biomedich-1001	98	92	reference	reference	NOUN
biomedich-1001	98	93	drug	drug	NOUN
biomedich-1001	98	94	(	(	PUNCT
biomedich-1001	98	95	allopurinol	allopurinol	NOUN
biomedich-1001	98	96	)	)	PUNCT
biomedich-1001	98	97	.	.	PUNCT
biomedich-1001	99	1	subsequently	subsequently	ADV
biomedich-1001	99	2	,	,	PUNCT
biomedich-1001	99	3	2	2	NUM
biomedich-1001	99	4	compounds	compound	NOUN
biomedich-1001	99	5	were	be	AUX
biomedich-1001	99	6	selected	select	VERB
biomedich-1001	99	7	which	which	PRON
biomedich-1001	99	8	have	have	VERB
biomedich-1001	99	9	low	low	ADJ
biomedich-1001	99	10	binding	bind	VERB
biomedich-1001	99	11	energy	energy	NOUN
biomedich-1001	99	12	(	(	PUNCT
biomedich-1001	99	13	δg	δg	NOUN
biomedich-1001	99	14	)	)	PUNCT
biomedich-1001	99	15	and	and	CCONJ
biomedich-1001	99	16	inhibition	inhibition	VERB
biomedich-1001	99	17	constant	constant	ADJ
biomedich-1001	99	18	(	(	PUNCT
biomedich-1001	99	19	ki	ki	ADJ
biomedich-1001	99	20	)	)	PUNCT
biomedich-1001	99	21	values	value	NOUN
biomedich-1001	99	22	and	and	CCONJ
biomedich-1001	99	23	meet	meet	VERB
biomedich-1001	99	24	the	the	DET
biomedich-1001	99	25	toxicity	toxicity	NOUN
biomedich-1001	99	26	,	,	PUNCT
biomedich-1001	99	27	pharmacokinetics	pharmacokinetic	NOUN
biomedich-1001	99	28	,	,	PUNCT
biomedich-1001	99	29	and	and	CCONJ
biomedich-1001	99	30	lipinski	lipinski	PROPN
biomedich-1001	99	31	’s	’s	PART
biomedich-1001	99	32	test	test	NOUN
biomedich-1001	99	33	criteria	criterion	NOUN
biomedich-1001	99	34	,	,	PUNCT
biomedich-1001	99	35	namely	namely	ADV
biomedich-1001	99	36	the	the	DET
biomedich-1001	99	37	compound	compound	NOUN
biomedich-1001	99	38	5hydroxy-3,7,4'-trimethoxyflavone	5hydroxy-3,7,4'-trimethoxyflavone	PROPN
biomedich-1001	99	39	with	with	ADP
biomedich-1001	99	40	a	a	DET
biomedich-1001	99	41	binding	bind	VERB
biomedich-1001	99	42	energy	energy	NOUN
biomedich-1001	99	43	value	value	NOUN
biomedich-1001	99	44	(	(	PUNCT
biomedich-1001	99	45	δg	δg	NOUN
biomedich-1001	99	46	)	)	PUNCT
biomedich-1001	99	47	of	of	ADP
biomedich-1001	99	48	-8.89	-8.89	NUM
biomedich-1001	99	49	kcal	kcal	NOUN
biomedich-1001	99	50	/	/	SYM
biomedich-1001	99	51	mol	mol	PROPN
biomedich-1001	99	52	and	and	CCONJ
biomedich-1001	99	53	an	an	DET
biomedich-1001	99	54	inhibition	inhibition	NOUN
biomedich-1001	99	55	constant	constant	ADJ
biomedich-1001	99	56	(	(	PUNCT
biomedich-1001	99	57	ki	ki	INTJ
biomedich-1001	99	58	)	)	PUNCT
biomedich-1001	99	59	of	of	ADP
biomedich-1001	99	60	306.54	306.54	NUM
biomedich-1001	99	61	nm	nm	NOUN
biomedich-1001	99	62	,	,	PUNCT
biomedich-1001	99	63	as	as	ADV
biomedich-1001	99	64	well	well	ADV
biomedich-1001	99	65	as	as	ADP
biomedich-1001	99	66	the	the	DET
biomedich-1001	99	67	compound	compound	NOUN
biomedich-1001	99	68	kaempferol	kaempferol	NOUN
biomedich-1001	99	69	with	with	ADP
biomedich-1001	99	70	a	a	DET
biomedich-1001	99	71	binding	bind	VERB
biomedich-1001	99	72	energy	energy	NOUN
biomedich-1001	99	73	of	of	ADP
biomedich-1001	99	74	-8.1	-8.1	PROPN
biomedich-1001	99	75	kcal	kcal	PROPN
biomedich-1001	99	76	/	/	SYM
biomedich-1001	99	77	mol	mol	PROPN
biomedich-1001	99	78	and	and	CCONJ
biomedich-1001	99	79	ki	ki	PROPN
biomedich-1001	99	80	of	of	ADP
biomedich-1001	99	81	1.15	1.15	NUM
biomedich-1001	99	82	µm	µm	NOUN
biomedich-1001	99	83	.	.	PUNCT
biomedich-1001	100	1	subsequently	subsequently	ADV
biomedich-1001	100	2	,	,	PUNCT
biomedich-1001	100	3	visualization	visualization	NOUN
biomedich-1001	100	4	was	be	AUX
biomedich-1001	100	5	performed	perform	VERB
biomedich-1001	100	6	using	use	VERB
biomedich-1001	100	7	the	the	DET
biomedich-1001	100	8	reference	reference	NOUN
biomedich-1001	100	9	drug	drug	NOUN
biomedich-1001	100	10	and	and	CCONJ
biomedich-1001	100	11	these	these	DET
biomedich-1001	100	12	selected	select	VERB
biomedich-1001	100	13	compounds	compound	NOUN
biomedich-1001	100	14	.	.	PUNCT
biomedich-1001	101	1	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	101	2	et	et	PROPN
biomedich-1001	101	3	al	al	PROPN
biomedich-1001	101	4	.	.	PUNCT
biomedich-1001	101	5	–	–	PUNCT
biomedich-1001	101	6	molecular	molecular	ADJ
biomedich-1001	101	7	dynamic	dynamic	ADJ
biomedich-1001	101	8	study	study	NOUN
biomedich-1001	101	9	of	of	ADP
biomedich-1001	101	10	java	java	PROPN
biomedich-1001	101	11	cardamom	cardamom	PROPN
biomedich-1001	101	12	(	(	PUNCT
biomedich-1001	101	13	wurfbania	wurfbania	PROPN
biomedich-1001	101	14	compacta	compacta	PROPN
biomedich-1001	101	15	)	)	PUNCT
biomedich-1001	101	16	…	…	PUNCT
biomedich-1001	101	17	1251	1251	NUM
biomedich-1001	101	18	table	table	NOUN
biomedich-1001	101	19	4	4	NUM
biomedich-1001	101	20	,	,	PUNCT
biomedich-1001	101	21	molecular	molecular	ADJ
biomedich-1001	101	22	docking	docking	NOUN
biomedich-1001	101	23	results	result	NOUN
biomedich-1001	101	24	.	.	PUNCT
biomedich-1001	102	1	no	no	DET
biomedich-1001	102	2	compounds	compound	NOUN
biomedich-1001	102	3	name	name	VERB
biomedich-1001	102	4	binding	bind	VERB
biomedich-1001	102	5	energy	energy	NOUN
biomedich-1001	102	6	(	(	PUNCT
biomedich-1001	102	7	kcal	kcal	NOUN
biomedich-1001	102	8	/	/	SYM
biomedich-1001	102	9	mol	mol	NOUN
biomedich-1001	102	10	)	)	PUNCT
biomedich-1001	102	11	ki	ki	PROPN
biomedich-1001	102	12	run	run	VERB
biomedich-1001	102	13	1	1	NUM
biomedich-1001	102	14	5	5	NUM
biomedich-1001	102	15	-	-	NUM
biomedich-1001	102	16	hidroksi-3,7,4'-trimetoksiflavon	hidroksi-3,7,4'-trimetoksiflavon	ADJ
biomedich-1001	102	17	-8,89	-8,89	PROPN
biomedich-1001	102	18	306,54	306,54	NUM
biomedich-1001	102	19	nm	nm	ADV
biomedich-1001	102	20	23	23	NUM
biomedich-1001	102	21	2	2	NUM
biomedich-1001	102	22	carvol	carvol	NOUN
biomedich-1001	102	23	-7,22	-7,22	PUNCT
biomedich-1001	103	1	5,09	5,09	NUM
biomedich-1001	103	2	um	um	INTJ
biomedich-1001	103	3	21	21	NUM
biomedich-1001	103	4	3	3	NUM
biomedich-1001	103	5	kaempferol	kaempferol	NOUN
biomedich-1001	103	6	-8,1	-8,1	PROPN
biomedich-1001	103	7	1,15	1,15	NUM
biomedich-1001	103	8	um	um	INTJ
biomedich-1001	103	9	70	70	NUM
biomedich-1001	103	10	4	4	NUM
biomedich-1001	103	11	allopurinol	allopurinol	NOUN
biomedich-1001	103	12	-5,83	-5,83	PUNCT
biomedich-1001	103	13	53,39	53,39	ADJ
biomedich-1001	103	14	µm	µm	ADP
biomedich-1001	103	15	(	(	PUNCT
biomedich-1001	103	16	a	a	NOUN
biomedich-1001	103	17	)	)	PUNCT
biomedich-1001	103	18	(	(	PUNCT
biomedich-1001	103	19	b	b	X
biomedich-1001	103	20	)	)	PUNCT
biomedich-1001	103	21	(	(	PUNCT
biomedich-1001	103	22	c	c	X
biomedich-1001	103	23	)	)	PUNCT
biomedich-1001	103	24	figure	figure	NOUN
biomedich-1001	103	25	5	5	NUM
biomedich-1001	103	26	visualization	visualization	NOUN
biomedich-1001	103	27	of	of	ADP
biomedich-1001	103	28	the	the	DET
biomedich-1001	103	29	interaction	interaction	NOUN
biomedich-1001	103	30	of	of	ADP
biomedich-1001	103	31	receptor	receptor	NOUN
biomedich-1001	103	32	3nvw	3nvw	ADV
biomedich-1001	103	33	with	with	ADP
biomedich-1001	103	34	compounds	compound	NOUN
biomedich-1001	103	35	(	(	PUNCT
biomedich-1001	103	36	a	a	PRON
biomedich-1001	103	37	)	)	PUNCT
biomedich-1001	103	38	allopurinol	allopurinol	NOUN
biomedich-1001	103	39	,	,	PUNCT
biomedich-1001	103	40	(	(	PUNCT
biomedich-1001	103	41	b	b	X
biomedich-1001	103	42	)	)	PUNCT
biomedich-1001	103	43	5	5	NUM
biomedich-1001	103	44	-	-	SYM
biomedich-1001	103	45	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	103	46	,	,	PUNCT
biomedich-1001	103	47	and	and	CCONJ
biomedich-1001	103	48	(	(	PUNCT
biomedich-1001	103	49	c	c	NOUN
biomedich-1001	103	50	)	)	PUNCT
biomedich-1001	103	51	kaempferol	kaempferol	NOUN
biomedich-1001	103	52	.	.	PUNCT
biomedich-1001	104	1	in	in	ADP
biomedich-1001	104	2	figure	figure	NOUN
biomedich-1001	104	3	4	4	NUM
biomedich-1001	104	4	and	and	CCONJ
biomedich-1001	104	5	table	table	NOUN
biomedich-1001	104	6	5	5	NUM
biomedich-1001	104	7	,	,	PUNCT
biomedich-1001	104	8	the	the	DET
biomedich-1001	104	9	visualization	visualization	NOUN
biomedich-1001	104	10	results	result	NOUN
biomedich-1001	104	11	show	show	VERB
biomedich-1001	104	12	that	that	SCONJ
biomedich-1001	104	13	the	the	DET
biomedich-1001	104	14	reference	reference	NOUN
biomedich-1001	104	15	drug	drug	NOUN
biomedich-1001	104	16	,	,	PUNCT
biomedich-1001	104	17	allopurinol	allopurinol	NOUN
biomedich-1001	104	18	,	,	PUNCT
biomedich-1001	104	19	forms	form	VERB
biomedich-1001	104	20	hydrogen	hydrogen	NOUN
biomedich-1001	104	21	bonds	bond	NOUN
biomedich-1001	104	22	with	with	ADP
biomedich-1001	104	23	the	the	DET
biomedich-1001	104	24	amino	amino	NOUN
biomedich-1001	104	25	acid	acid	NOUN
biomedich-1001	104	26	residues	residue	NOUN
biomedich-1001	104	27	ala1079	ala1079	PROPN
biomedich-1001	104	28	,	,	PUNCT
biomedich-1001	104	29	arg880	arg880	ADJ
biomedich-1001	104	30	,	,	PUNCT
biomedich-1001	104	31	thr1010	thr1010	NOUN
biomedich-1001	104	32	,	,	PUNCT
biomedich-1001	104	33	and	and	CCONJ
biomedich-1001	104	34	glu1261	glu1261	NOUN
biomedich-1001	104	35	.	.	PUNCT
biomedich-1001	105	1	in	in	ADP
biomedich-1001	105	2	the	the	DET
biomedich-1001	105	3	compound	compound	NOUN
biomedich-1001	105	4	5	5	NUM
biomedich-1001	105	5	-	-	PUNCT
biomedich-1001	105	6	hydroxy3,7,4'-trimethoxyflavone	hydroxy3,7,4'-trimethoxyflavone	NOUN
biomedich-1001	105	7	,	,	PUNCT
biomedich-1001	105	8	hydrogen	hydrogen	NOUN
biomedich-1001	105	9	bonds	bond	NOUN
biomedich-1001	105	10	are	be	AUX
biomedich-1001	105	11	formed	form	VERB
biomedich-1001	105	12	with	with	ADP
biomedich-1001	105	13	the	the	DET
biomedich-1001	105	14	amino	amino	NOUN
biomedich-1001	105	15	acid	acid	NOUN
biomedich-1001	105	16	residues	residue	NOUN
biomedich-1001	105	17	arg880	arg880	ADJ
biomedich-1001	105	18	,	,	PUNCT
biomedich-1001	105	19	thr1010	thr1010	NOUN
biomedich-1001	105	20	,	,	PUNCT
biomedich-1001	105	21	phe1009	phe1009	NOUN
biomedich-1001	105	22	,	,	PUNCT
biomedich-1001	105	23	and	and	CCONJ
biomedich-1001	105	24	there	there	PRON
biomedich-1001	105	25	are	be	VERB
biomedich-1001	105	26	similarities	similarity	NOUN
biomedich-1001	105	27	with	with	ADP
biomedich-1001	105	28	allopurinol	allopurinol	NOUN
biomedich-1001	105	29	,	,	PUNCT
biomedich-1001	105	30	namely	namely	ADV
biomedich-1001	105	31	arg880	arg880	ADJ
biomedich-1001	105	32	and	and	CCONJ
biomedich-1001	105	33	thr1010	thr1010	NOUN
biomedich-1001	105	34	.	.	PUNCT
biomedich-1001	106	1	meanwhile	meanwhile	ADV
biomedich-1001	106	2	,	,	PUNCT
biomedich-1001	106	3	in	in	ADP
biomedich-1001	106	4	the	the	DET
biomedich-1001	106	5	kaempferol	kaempferol	NOUN
biomedich-1001	106	6	compound	compound	NOUN
biomedich-1001	106	7	,	,	PUNCT
biomedich-1001	106	8	hydrogen	hydrogen	NOUN
biomedich-1001	106	9	bonds	bond	NOUN
biomedich-1001	106	10	are	be	AUX
biomedich-1001	106	11	formed	form	VERB
biomedich-1001	106	12	with	with	ADP
biomedich-1001	106	13	the	the	DET
biomedich-1001	106	14	amino	amino	NOUN
biomedich-1001	106	15	acid	acid	NOUN
biomedich-1001	106	16	residues	residue	NOUN
biomedich-1001	106	17	arg880	arg880	ADJ
biomedich-1001	106	18	,	,	PUNCT
biomedich-1001	106	19	thr1010	thr1010	NOUN
biomedich-1001	106	20	,	,	PUNCT
biomedich-1001	106	21	val1011	val1011	NOUN
biomedich-1001	106	22	,	,	PUNCT
biomedich-1001	106	23	glu1261	glu1261	NOUN
biomedich-1001	106	24	,	,	PUNCT
biomedich-1001	106	25	phe1009	phe1009	NOUN
biomedich-1001	106	26	,	,	PUNCT
biomedich-1001	106	27	and	and	CCONJ
biomedich-1001	106	28	it	it	PRON
biomedich-1001	106	29	shares	share	VERB
biomedich-1001	106	30	3	3	NUM
biomedich-1001	106	31	amino	amino	NOUN
biomedich-1001	106	32	acid	acid	NOUN
biomedich-1001	106	33	residues	residue	NOUN
biomedich-1001	106	34	with	with	ADP
biomedich-1001	106	35	allopurinol	allopurinol	NOUN
biomedich-1001	106	36	,	,	PUNCT
biomedich-1001	106	37	namely	namely	ADV
biomedich-1001	106	38	arg880	arg880	ADJ
biomedich-1001	106	39	,	,	PUNCT
biomedich-1001	106	40	thr1010	thr1010	NOUN
biomedich-1001	106	41	,	,	PUNCT
biomedich-1001	106	42	and	and	CCONJ
biomedich-1001	106	43	glu1261	glu1261	NOUN
biomedich-1001	106	44	.	.	PUNCT
biomedich-1001	107	1	in	in	ADP
biomedich-1001	107	2	addition	addition	NOUN
biomedich-1001	107	3	to	to	ADP
biomedich-1001	107	4	the	the	DET
biomedich-1001	107	5	amino	amino	NOUN
biomedich-1001	107	6	acid	acid	NOUN
biomedich-1001	107	7	residues	residue	NOUN
biomedich-1001	107	8	involved	involve	VERB
biomedich-1001	107	9	in	in	ADP
biomedich-1001	107	10	hydrogen	hydrogen	NOUN
biomedich-1001	107	11	bonds	bond	NOUN
biomedich-1001	107	12	,	,	PUNCT
biomedich-1001	107	13	there	there	PRON
biomedich-1001	107	14	are	be	VERB
biomedich-1001	107	15	also	also	ADV
biomedich-1001	107	16	amino	amino	NOUN
biomedich-1001	107	17	acid	acid	NOUN
biomedich-1001	107	18	residues	residue	NOUN
biomedich-1001	107	19	involved	involve	VERB
biomedich-1001	107	20	in	in	ADP
biomedich-1001	107	21	hydrophobic	hydrophobic	NOUN
biomedich-1001	107	22	bonds	bond	NOUN
biomedich-1001	107	23	.	.	PUNCT
biomedich-1001	108	1	in	in	ADP
biomedich-1001	108	2	allopurinol	allopurinol	NOUN
biomedich-1001	108	3	,	,	PUNCT
biomedich-1001	108	4	the	the	DET
biomedich-1001	108	5	amino	amino	NOUN
biomedich-1001	108	6	acid	acid	NOUN
biomedich-1001	108	7	residues	residue	NOUN
biomedich-1001	108	8	that	that	PRON
biomedich-1001	108	9	participate	participate	VERB
biomedich-1001	108	10	in	in	ADP
biomedich-1001	108	11	hydrophobic	hydrophobic	NOUN
biomedich-1001	108	12	bonding	bonding	NOUN
biomedich-1001	108	13	are	be	AUX
biomedich-1001	108	14	phe914	phe914	PROPN
biomedich-1001	108	15	and	and	CCONJ
biomedich-1001	108	16	ala1078	ala1078	ADJ
biomedich-1001	108	17	.	.	PUNCT
biomedich-1001	109	1	in	in	ADP
biomedich-1001	109	2	the	the	DET
biomedich-1001	109	3	compound	compound	NOUN
biomedich-1001	109	4	5hydroxy-3,7,4'-trimethoxyflavone	5hydroxy-3,7,4'-trimethoxyflavone	PROPN
biomedich-1001	109	5	,	,	PUNCT
biomedich-1001	109	6	the	the	DET
biomedich-1001	109	7	residues	residue	NOUN
biomedich-1001	109	8	that	that	PRON
biomedich-1001	109	9	contribute	contribute	VERB
biomedich-1001	109	10	to	to	ADP
biomedich-1001	109	11	hydrophobic	hydrophobic	NOUN
biomedich-1001	109	12	bonding	bonding	NOUN
biomedich-1001	109	13	are	be	AUX
biomedich-1001	109	14	ala1078	ala1078	ADJ
biomedich-1001	109	15	,	,	PUNCT
biomedich-1001	109	16	ala1079	ala1079	PROPN
biomedich-1001	109	17	,	,	PUNCT
biomedich-1001	109	18	phe914	phe914	PROPN
biomedich-1001	109	19	,	,	PUNCT
biomedich-1001	109	20	ala910	ala910	PROPN
biomedich-1001	109	21	,	,	PUNCT
biomedich-1001	109	22	leu1014	leu1014	NOUN
biomedich-1001	109	23	,	,	PUNCT
biomedich-1001	109	24	leu873	leu873	PROPN
biomedich-1001	109	25	,	,	PUNCT
biomedich-1001	109	26	val1011	val1011	NOUN
biomedich-1001	109	27	,	,	PUNCT
biomedich-1001	109	28	and	and	CCONJ
biomedich-1001	109	29	has	have	VERB
biomedich-1001	109	30	2	2	NUM
biomedich-1001	109	31	amino	amino	NOUN
biomedich-1001	109	32	acid	acid	NOUN
biomedich-1001	109	33	residues	residue	NOUN
biomedich-1001	109	34	that	that	PRON
biomedich-1001	109	35	are	be	AUX
biomedich-1001	109	36	the	the	DET
biomedich-1001	109	37	same	same	ADJ
biomedich-1001	109	38	as	as	ADP
biomedich-1001	109	39	allopurinol	allopurinol	NOUN
biomedich-1001	109	40	,	,	PUNCT
biomedich-1001	109	41	namely	namely	ADV
biomedich-1001	109	42	phe914	phe914	PROPN
biomedich-1001	109	43	and	and	CCONJ
biomedich-1001	109	44	ala1078	ala1078	ADJ
biomedich-1001	109	45	.	.	PUNCT
biomedich-1001	110	1	table	table	NOUN
biomedich-1001	110	2	5	5	NUM
biomedich-1001	110	3	.	.	PUNCT
biomedich-1001	111	1	results	result	NOUN
biomedich-1001	111	2	of	of	ADP
biomedich-1001	111	3	the	the	DET
biomedich-1001	111	4	visualization	visualization	NOUN
biomedich-1001	111	5	of	of	ADP
biomedich-1001	111	6	the	the	DET
biomedich-1001	111	7	interaction	interaction	NOUN
biomedich-1001	111	8	bonds	bond	NOUN
biomedich-1001	111	9	between	between	ADP
biomedich-1001	111	10	5	5	NUM
biomedich-1001	111	11	-	-	SYM
biomedich-1001	111	12	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	111	13	,	,	PUNCT
biomedich-1001	111	14	kaempferol	kaempferol	NOUN
biomedich-1001	111	15	,	,	PUNCT
biomedich-1001	111	16	and	and	CCONJ
biomedich-1001	111	17	allopurinol	allopurinol	VERB
biomedich-1001	111	18	towards	towards	ADP
biomedich-1001	111	19	the	the	DET
biomedich-1001	111	20	receptor	receptor	NOUN
biomedich-1001	111	21	.	.	PUNCT
biomedich-1001	112	1	no	no	DET
biomedich-1001	112	2	compounds	compound	NOUN
biomedich-1001	112	3	name	name	NOUN
biomedich-1001	112	4	hydrogen	hydrogen	NOUN
biomedich-1001	112	5	bond	bond	NOUN
biomedich-1001	112	6	hydrophobic	hydrophobic	NOUN
biomedich-1001	112	7	bonds	bond	NOUN
biomedich-1001	112	8	1	1	NUM
biomedich-1001	112	9	5	5	NUM
biomedich-1001	112	10	-	-	PUNCT
biomedich-1001	112	11	hidroksi-3,7,4'-trimetoksiflavon	hidroksi-3,7,4'-trimetoksiflavon	ADJ
biomedich-1001	112	12	arg880	arg880	PROPN
biomedich-1001	112	13	,	,	PUNCT
biomedich-1001	112	14	thr1010	thr1010	NOUN
biomedich-1001	112	15	,	,	PUNCT
biomedich-1001	112	16	phe1009	phe1009	NOUN
biomedich-1001	112	17	ala1078	ala1078	PROPN
biomedich-1001	112	18	,	,	PUNCT
biomedich-1001	112	19	ala1079	ala1079	PROPN
biomedich-1001	112	20	,	,	PUNCT
biomedich-1001	112	21	phe914	phe914	PROPN
biomedich-1001	112	22	,	,	PUNCT
biomedich-1001	112	23	ala910	ala910	PROPN
biomedich-1001	112	24	,	,	PUNCT
biomedich-1001	112	25	leu1014	leu1014	NOUN
biomedich-1001	112	26	,	,	PUNCT
biomedich-1001	112	27	leu873	leu873	PROPN
biomedich-1001	112	28	,	,	PUNCT
biomedich-1001	112	29	val1011	val1011	NOUN
biomedich-1001	112	30	2	2	NUM
biomedich-1001	112	31	kaempferol	kaempferol	NOUN
biomedich-1001	112	32	arg880	arg880	ADJ
biomedich-1001	112	33	,	,	PUNCT
biomedich-1001	112	34	thr1010	thr1010	NOUN
biomedich-1001	112	35	,	,	PUNCT
biomedich-1001	112	36	val1011	val1011	NOUN
biomedich-1001	112	37	,	,	PUNCT
biomedich-1001	112	38	glu1261	glu1261	NOUN
biomedich-1001	112	39	,	,	PUNCT
biomedich-1001	112	40	phe1009	phe1009	NOUN
biomedich-1001	112	41	ala1078	ala1078	PROPN
biomedich-1001	112	42	,	,	PUNCT
biomedich-1001	112	43	ala1079	ala1079	PROPN
biomedich-1001	112	44	,	,	PUNCT
biomedich-1001	112	45	phe914	phe914	PROPN
biomedich-1001	112	46	,	,	PUNCT
biomedich-1001	112	47	ala910	ala910	PROPN
biomedich-1001	112	48	,	,	PUNCT
biomedich-1001	112	49	leu1014	leu1014	NOUN
biomedich-1001	112	50	,	,	PUNCT
biomedich-1001	112	51	leu873	leu873	PROPN
biomedich-1001	112	52	3	3	NUM
biomedich-1001	112	53	allopurinol	allopurinol	NOUN
biomedich-1001	112	54	ala1079	ala1079	PROPN
biomedich-1001	112	55	,	,	PUNCT
biomedich-1001	112	56	arg880	arg880	PROPN
biomedich-1001	112	57	,	,	PUNCT
biomedich-1001	112	58	thr1010	thr1010	NOUN
biomedich-1001	112	59	,	,	PUNCT
biomedich-1001	112	60	glu1261	glu1261	ADJ
biomedich-1001	112	61	phe914	phe914	PROPN
biomedich-1001	112	62	,	,	PUNCT
biomedich-1001	112	63	ala1078	ala1078	ADV
biomedich-1001	112	64	,	,	PUNCT
biomedich-1001	112	65	val1010	val1010	NOUN
biomedich-1001	112	66	result	result	NOUN
biomedich-1001	112	67	of	of	ADP
biomedich-1001	112	68	molecular	molecular	ADJ
biomedich-1001	112	69	dynamic	dynamic	ADJ
biomedich-1001	112	70	simulation	simulation	NOUN
biomedich-1001	112	71	the	the	DET
biomedich-1001	112	72	selected	select	VERB
biomedich-1001	112	73	test	test	NOUN
biomedich-1001	112	74	compounds	compound	NOUN
biomedich-1001	112	75	are	be	AUX
biomedich-1001	112	76	5	5	NUM
biomedich-1001	112	77	-	-	PUNCT
biomedich-1001	112	78	hydroxy-3,7,4'trimethoxyflavone	hydroxy-3,7,4'trimethoxyflavone	NOUN
biomedich-1001	112	79	and	and	CCONJ
biomedich-1001	112	80	kaempferol	kaempferol	NOUN
biomedich-1001	112	81	,	,	PUNCT
biomedich-1001	112	82	along	along	ADP
biomedich-1001	112	83	with	with	ADP
biomedich-1001	112	84	the	the	DET
biomedich-1001	112	85	comparator	comparator	NOUN
biomedich-1001	112	86	drug	drug	NOUN
biomedich-1001	112	87	(	(	PUNCT
biomedich-1001	112	88	allopurinol	allopurinol	NOUN
biomedich-1001	112	89	)	)	PUNCT
biomedich-1001	112	90	,	,	PUNCT
biomedich-1001	112	91	and	and	CCONJ
biomedich-1001	112	92	will	will	AUX
biomedich-1001	112	93	proceed	proceed	VERB
biomedich-1001	112	94	to	to	ADP
biomedich-1001	112	95	the	the	DET
biomedich-1001	112	96	molecular	molecular	ADJ
biomedich-1001	112	97	dynamics	dynamic	NOUN
biomedich-1001	112	98	simulation	simulation	NOUN
biomedich-1001	112	99	stage	stage	NOUN
biomedich-1001	112	100	using	use	VERB
biomedich-1001	112	101	desmond	desmond	PROPN
biomedich-1001	112	102	software	software	NOUN
biomedich-1001	112	103	.	.	PUNCT
biomedich-1001	113	1	the	the	DET
biomedich-1001	113	2	result	result	NOUN
biomedich-1001	113	3	can	can	AUX
biomedich-1001	113	4	be	be	AUX
biomedich-1001	113	5	seen	see	VERB
biomedich-1001	113	6	in	in	ADP
biomedich-1001	113	7	figure	figure	NOUN
biomedich-1001	113	8	5	5	NUM
biomedich-1001	113	9	.	.	SYM
biomedich-1001	113	10	1252	1252	NUM
biomedich-1001	113	11	biology	biology	NOUN
biomedich-1001	113	12	,	,	PUNCT
biomedich-1001	113	13	medicine	medicine	NOUN
biomedich-1001	113	14	,	,	PUNCT
biomedich-1001	113	15	&	&	CCONJ
biomedich-1001	113	16	natural	natural	ADJ
biomedich-1001	113	17	product	product	NOUN
biomedich-1001	113	18	chemistry	chemistry	NOUN
biomedich-1001	113	19	14	14	NUM
biomedich-1001	113	20	(	(	PUNCT
biomedich-1001	113	21	2	2	NUM
biomedich-1001	113	22	)	)	PUNCT
biomedich-1001	113	23	,	,	PUNCT
biomedich-1001	113	24	2025	2025	NUM
biomedich-1001	113	25	:	:	PUNCT
biomedich-1001	113	26	1247	1247	NUM
biomedich-1001	113	27	-	-	SYM
biomedich-1001	113	28	1256	1256	NUM
biomedich-1001	113	29	figure	figure	NOUN
biomedich-1001	113	30	6	6	NUM
biomedich-1001	113	31	.	.	PUNCT
biomedich-1001	113	32	rmsd	rmsd	NOUN
biomedich-1001	113	33	value	value	NOUN
biomedich-1001	113	34	graph	graph	NOUN
biomedich-1001	113	35	of	of	ADP
biomedich-1001	113	36	allopurinol	allopurinol	NOUN
biomedich-1001	113	37	,	,	PUNCT
biomedich-1001	113	38	5	5	NUM
biomedich-1001	113	39	-	-	SYM
biomedich-1001	113	40	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NOUN
biomedich-1001	113	41	and	and	CCONJ
biomedich-1001	113	42	kaempferol	kaempferol	NOUN
biomedich-1001	113	43	.	.	PUNCT
biomedich-1001	114	1	based	base	VERB
biomedich-1001	114	2	on	on	ADP
biomedich-1001	114	3	the	the	DET
biomedich-1001	114	4	figure	figure	NOUN
biomedich-1001	114	5	5	5	NUM
biomedich-1001	114	6	indicate	indicate	VERB
biomedich-1001	114	7	an	an	DET
biomedich-1001	114	8	increase	increase	NOUN
biomedich-1001	114	9	.	.	PUNCT
biomedich-1001	115	1	the	the	DET
biomedich-1001	115	2	rmsd	rmsd	ADJ
biomedich-1001	115	3	value	value	NOUN
biomedich-1001	115	4	for	for	ADP
biomedich-1001	115	5	allopurinol	allopurinol	NOUN
biomedich-1001	115	6	starts	start	NOUN
biomedich-1001	115	7	stabilizing	stabilize	VERB
biomedich-1001	115	8	at	at	ADP
biomedich-1001	115	9	30	30	NUM
biomedich-1001	115	10	-	-	SYM
biomedich-1001	115	11	50	50	NUM
biomedich-1001	115	12	ns	ns	NOUN
biomedich-1001	115	13	with	with	ADP
biomedich-1001	115	14	an	an	DET
biomedich-1001	115	15	rmsd	rmsd	ADJ
biomedich-1001	115	16	value	value	NOUN
biomedich-1001	115	17	of	of	ADP
biomedich-1001	115	18	±	±	NUM
biomedich-1001	115	19	2.7	2.7	NUM
biomedich-1001	115	20	å	å	NOUN
biomedich-1001	115	21	,	,	PUNCT
biomedich-1001	115	22	then	then	ADV
biomedich-1001	115	23	fluctuates	fluctuate	NOUN
biomedich-1001	115	24	and	and	CCONJ
biomedich-1001	115	25	stabilizes	stabilize	VERB
biomedich-1001	115	26	again	again	ADV
biomedich-1001	115	27	from	from	ADP
biomedich-1001	115	28	60	60	NUM
biomedich-1001	115	29	-	-	SYM
biomedich-1001	115	30	80	80	NUM
biomedich-1001	115	31	ns	ns	NOUN
biomedich-1001	115	32	with	with	ADP
biomedich-1001	115	33	an	an	DET
biomedich-1001	115	34	rmsd	rmsd	ADJ
biomedich-1001	115	35	value	value	NOUN
biomedich-1001	115	36	of	of	ADP
biomedich-1001	115	37	±	±	NUM
biomedich-1001	115	38	3	3	NUM
biomedich-1001	115	39	å	å	PROPN
biomedich-1001	115	40	,	,	PUNCT
biomedich-1001	115	41	after	after	ADP
biomedich-1001	115	42	which	which	PRON
biomedich-1001	115	43	it	it	PRON
biomedich-1001	115	44	fluctuates	fluctuate	VERB
biomedich-1001	115	45	again	again	ADV
biomedich-1001	115	46	and	and	CCONJ
biomedich-1001	115	47	stabilizes	stabilize	VERB
biomedich-1001	115	48	at	at	ADP
biomedich-1001	115	49	93100	93100	NUM
biomedich-1001	115	50	ns	ns	NUM
biomedich-1001	115	51	with	with	ADP
biomedich-1001	115	52	an	an	DET
biomedich-1001	115	53	rmsd	rmsd	ADJ
biomedich-1001	115	54	value	value	NOUN
biomedich-1001	115	55	of	of	ADP
biomedich-1001	115	56	±	±	NUM
biomedich-1001	115	57	3	3	NUM
biomedich-1001	115	58	å	å	NOUN
biomedich-1001	115	59	.	.	PUNCT
biomedich-1001	116	1	for	for	ADP
biomedich-1001	116	2	the	the	DET
biomedich-1001	116	3	compound	compound	NOUN
biomedich-1001	116	4	5	5	NUM
biomedich-1001	116	5	-	-	SYM
biomedich-1001	116	6	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	116	7	,	,	PUNCT
biomedich-1001	116	8	it	it	PRON
biomedich-1001	116	9	starts	start	VERB
biomedich-1001	116	10	stabilizing	stabilize	VERB
biomedich-1001	116	11	at	at	ADP
biomedich-1001	116	12	30	30	NUM
biomedich-1001	116	13	-	-	SYM
biomedich-1001	116	14	40	40	NUM
biomedich-1001	116	15	ns	ns	NUM
biomedich-1001	116	16	with	with	ADP
biomedich-1001	116	17	an	an	DET
biomedich-1001	116	18	rmsd	rmsd	ADJ
biomedich-1001	116	19	value	value	NOUN
biomedich-1001	116	20	of	of	ADP
biomedich-1001	116	21	±	±	NUM
biomedich-1001	116	22	2.3	2.3	NUM
biomedich-1001	116	23	å	å	NOUN
biomedich-1001	116	24	,	,	PUNCT
biomedich-1001	116	25	then	then	ADV
biomedich-1001	116	26	fluctuates	fluctuate	NOUN
biomedich-1001	116	27	and	and	CCONJ
biomedich-1001	116	28	stabilizes	stabilize	VERB
biomedich-1001	116	29	again	again	ADV
biomedich-1001	116	30	from	from	ADP
biomedich-1001	116	31	44	44	NUM
biomedich-1001	116	32	-	-	SYM
biomedich-1001	116	33	58	58	NUM
biomedich-1001	116	34	ns	ns	NOUN
biomedich-1001	116	35	with	with	ADP
biomedich-1001	116	36	an	an	DET
biomedich-1001	116	37	rmsd	rmsd	ADJ
biomedich-1001	116	38	value	value	NOUN
biomedich-1001	116	39	of	of	ADP
biomedich-1001	116	40	±	±	NUM
biomedich-1001	116	41	2.5	2.5	NUM
biomedich-1001	116	42	å	å	PROPN
biomedich-1001	116	43	,	,	PUNCT
biomedich-1001	116	44	fluctuates	fluctuate	VERB
biomedich-1001	116	45	again	again	ADV
biomedich-1001	116	46	,	,	PUNCT
biomedich-1001	116	47	and	and	CCONJ
biomedich-1001	116	48	stabilizes	stabilize	VERB
biomedich-1001	116	49	at	at	ADP
biomedich-1001	116	50	70	70	NUM
biomedich-1001	116	51	-	-	SYM
biomedich-1001	116	52	77	77	NUM
biomedich-1001	116	53	ns	ns	NUM
biomedich-1001	116	54	and	and	CCONJ
biomedich-1001	116	55	80	80	NUM
biomedich-1001	116	56	-	-	SYM
biomedich-1001	116	57	85	85	NUM
biomedich-1001	116	58	ns	ns	NOUN
biomedich-1001	116	59	with	with	ADP
biomedich-1001	116	60	an	an	DET
biomedich-1001	116	61	rmsd	rmsd	ADJ
biomedich-1001	116	62	value	value	NOUN
biomedich-1001	116	63	of	of	ADP
biomedich-1001	116	64	±	±	NUM
biomedich-1001	116	65	2.4	2.4	NUM
biomedich-1001	116	66	å	å	NOUN
biomedich-1001	116	67	.	.	PUNCT
biomedich-1001	117	1	for	for	ADP
biomedich-1001	117	2	the	the	DET
biomedich-1001	117	3	kaempferol	kaempferol	NOUN
biomedich-1001	117	4	compound	compound	NOUN
biomedich-1001	117	5	,	,	PUNCT
biomedich-1001	117	6	it	it	PRON
biomedich-1001	117	7	starts	start	VERB
biomedich-1001	117	8	stabilizing	stabilize	VERB
biomedich-1001	117	9	at	at	ADP
biomedich-1001	117	10	40	40	NUM
biomedich-1001	117	11	-	-	SYM
biomedich-1001	117	12	56	56	NUM
biomedich-1001	117	13	ns	ns	NOUN
biomedich-1001	117	14	with	with	ADP
biomedich-1001	117	15	an	an	DET
biomedich-1001	117	16	rmsd	rmsd	ADJ
biomedich-1001	117	17	value	value	NOUN
biomedich-1001	117	18	of	of	ADP
biomedich-1001	117	19	±	±	NUM
biomedich-1001	117	20	1.9	1.9	NUM
biomedich-1001	117	21	å	å	PROPN
biomedich-1001	117	22	,	,	PUNCT
biomedich-1001	117	23	then	then	ADV
biomedich-1001	117	24	fluctuates	fluctuate	NOUN
biomedich-1001	117	25	and	and	CCONJ
biomedich-1001	117	26	stabilizes	stabilize	VERB
biomedich-1001	117	27	again	again	ADV
biomedich-1001	117	28	at	at	ADP
biomedich-1001	117	29	57	57	NUM
biomedich-1001	117	30	-	-	SYM
biomedich-1001	117	31	64	64	NUM
biomedich-1001	117	32	ns	ns	NUM
biomedich-1001	117	33	with	with	ADP
biomedich-1001	117	34	an	an	DET
biomedich-1001	117	35	rmsd	rmsd	ADJ
biomedich-1001	117	36	value	value	NOUN
biomedich-1001	117	37	of	of	ADP
biomedich-1001	117	38	±	±	NUM
biomedich-1001	117	39	1.8	1.8	NUM
biomedich-1001	117	40	å	å	NOUN
biomedich-1001	117	41	,	,	PUNCT
biomedich-1001	117	42	then	then	ADV
biomedich-1001	117	43	fluctuates	fluctuate	VERB
biomedich-1001	117	44	again	again	ADV
biomedich-1001	117	45	and	and	CCONJ
biomedich-1001	117	46	stabilizes	stabilize	VERB
biomedich-1001	117	47	at	at	ADP
biomedich-1001	117	48	95	95	NUM
biomedich-1001	117	49	-	-	SYM
biomedich-1001	117	50	100	100	NUM
biomedich-1001	117	51	ns	ns	NUM
biomedich-1001	117	52	with	with	ADP
biomedich-1001	117	53	an	an	DET
biomedich-1001	117	54	rmsd	rmsd	ADJ
biomedich-1001	117	55	value	value	NOUN
biomedich-1001	117	56	of	of	ADP
biomedich-1001	117	57	±	±	NUM
biomedich-1001	118	1	1.8	1.8	NUM
biomedich-1001	118	2	å	å	NOUN
biomedich-1001	118	3	.	.	PUNCT
biomedich-1001	118	4	figure	figure	NOUN
biomedich-1001	118	5	7	7	NUM
biomedich-1001	118	6	.	.	PUNCT
biomedich-1001	118	7	rmsf	rmsf	NOUN
biomedich-1001	118	8	values	value	NOUN
biomedich-1001	118	9	of	of	ADP
biomedich-1001	118	10	allopurinol	allopurinol	NOUN
biomedich-1001	118	11	,	,	PUNCT
biomedich-1001	118	12	5	5	NUM
biomedich-1001	118	13	-	-	SYM
biomedich-1001	118	14	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NOUN
biomedich-1001	118	15	and	and	CCONJ
biomedich-1001	118	16	kaempferol	kaempferol	NOUN
biomedich-1001	118	17	.	.	PUNCT
biomedich-1001	119	1	the	the	DET
biomedich-1001	119	2	root	root	NOUN
biomedich-1001	119	3	mean	mean	VERB
biomedich-1001	119	4	square	square	ADJ
biomedich-1001	119	5	fluctuation	fluctuation	NOUN
biomedich-1001	119	6	parameter	parameter	NOUN
biomedich-1001	119	7	or	or	CCONJ
biomedich-1001	119	8	rmsf	rmsf	NOUN
biomedich-1001	119	9	is	be	AUX
biomedich-1001	119	10	analyzed	analyze	VERB
biomedich-1001	119	11	to	to	PART
biomedich-1001	119	12	determine	determine	VERB
biomedich-1001	119	13	the	the	DET
biomedich-1001	119	14	fluctuations	fluctuation	NOUN
biomedich-1001	119	15	of	of	ADP
biomedich-1001	119	16	ligand	ligand	ADJ
biomedich-1001	119	17	interactions	interaction	NOUN
biomedich-1001	119	18	with	with	ADP
biomedich-1001	119	19	amino	amino	ADJ
biomedich-1001	119	20	acids	acid	NOUN
biomedich-1001	119	21	during	during	ADP
biomedich-1001	119	22	the	the	DET
biomedich-1001	119	23	simulation15	simulation15	NOUN
biomedich-1001	119	24	.	.	PUNCT
biomedich-1001	120	1	based	base	VERB
biomedich-1001	120	2	on	on	ADP
biomedich-1001	120	3	the	the	DET
biomedich-1001	120	4	rmsf	rmsf	NOUN
biomedich-1001	120	5	analysis	analysis	NOUN
biomedich-1001	120	6	results	result	NOUN
biomedich-1001	120	7	in	in	ADP
biomedich-1001	120	8	figure	figure	NOUN
biomedich-1001	120	9	7	7	NUM
biomedich-1001	120	10	,	,	PUNCT
biomedich-1001	120	11	it	it	PRON
biomedich-1001	120	12	can	can	AUX
biomedich-1001	120	13	be	be	AUX
biomedich-1001	120	14	seen	see	VERB
biomedich-1001	120	15	that	that	SCONJ
biomedich-1001	120	16	the	the	DET
biomedich-1001	120	17	fluctuations	fluctuation	NOUN
biomedich-1001	120	18	of	of	ADP
biomedich-1001	120	19	the	the	DET
biomedich-1001	120	20	compounds	compound	NOUN
biomedich-1001	120	21	allopurinol	allopurinol	NOUN
biomedich-1001	120	22	,	,	PUNCT
biomedich-1001	120	23	5	5	NUM
biomedich-1001	120	24	-	-	SYM
biomedich-1001	120	25	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	120	26	,	,	PUNCT
biomedich-1001	120	27	and	and	CCONJ
biomedich-1001	120	28	kaempferol	kaempferol	NOUN
biomedich-1001	120	29	show	show	VERB
biomedich-1001	120	30	almost	almost	ADV
biomedich-1001	120	31	identical	identical	ADJ
biomedich-1001	120	32	fluctuation	fluctuation	NOUN
biomedich-1001	120	33	movements	movement	NOUN
biomedich-1001	120	34	.	.	PUNCT
biomedich-1001	121	1	based	base	VERB
biomedich-1001	121	2	on	on	ADP
biomedich-1001	121	3	the	the	DET
biomedich-1001	121	4	analysis	analysis	NOUN
biomedich-1001	121	5	results	result	NOUN
biomedich-1001	121	6	in	in	ADP
biomedich-1001	121	7	table	table	NOUN
biomedich-1001	121	8	6	6	NUM
biomedich-1001	121	9	,	,	PUNCT
biomedich-1001	121	10	the	the	DET
biomedich-1001	121	11	compound	compound	NOUN
biomedich-1001	121	12	5	5	NUM
biomedich-1001	121	13	-	-	PUNCT
biomedich-1001	121	14	hydroxy3,7,4'-trimethoxyflavone	hydroxy3,7,4'-trimethoxyflavone	NOUN
biomedich-1001	121	15	has	have	VERB
biomedich-1001	121	16	2	2	NUM
biomedich-1001	121	17	amino	amino	NOUN
biomedich-1001	121	18	acid	acid	NOUN
biomedich-1001	121	19	similarities	similarity	NOUN
biomedich-1001	121	20	with	with	ADP
biomedich-1001	121	21	allopurinol	allopurinol	NOUN
biomedich-1001	121	22	as	as	ADP
biomedich-1001	121	23	a	a	DET
biomedich-1001	121	24	comparison	comparison	NOUN
biomedich-1001	121	25	,	,	PUNCT
biomedich-1001	121	26	which	which	PRON
biomedich-1001	121	27	are	be	AUX
biomedich-1001	121	28	glu802	glu802	PROPN
biomedich-1001	121	29	and	and	CCONJ
biomedich-1001	121	30	ser876	ser876	NOUN
biomedich-1001	121	31	.	.	PUNCT
biomedich-1001	122	1	meanwhile	meanwhile	ADV
biomedich-1001	122	2	,	,	PUNCT
biomedich-1001	122	3	the	the	DET
biomedich-1001	122	4	compound	compound	NOUN
biomedich-1001	122	5	kaempferol	kaempferol	NOUN
biomedich-1001	122	6	has	have	VERB
biomedich-1001	122	7	3	3	NUM
biomedich-1001	122	8	amino	amino	NOUN
biomedich-1001	122	9	acid	acid	NOUN
biomedich-1001	122	10	similarities	similarity	NOUN
biomedich-1001	122	11	with	with	ADP
biomedich-1001	122	12	allopurinol	allopurinol	NOUN
biomedich-1001	122	13	,	,	PUNCT
biomedich-1001	122	14	namely	namely	ADV
biomedich-1001	122	15	thr1010	thr1010	NOUN
biomedich-1001	122	16	,	,	PUNCT
biomedich-1001	122	17	val1011	val1011	NOUN
biomedich-1001	122	18	,	,	PUNCT
biomedich-1001	122	19	and	and	CCONJ
biomedich-1001	122	20	ala1078	ala1078	ADJ
biomedich-1001	122	21	.	.	PUNCT
biomedich-1001	123	1	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	123	2	et	et	PROPN
biomedich-1001	123	3	al	al	PROPN
biomedich-1001	123	4	.	.	PUNCT
biomedich-1001	123	5	–	–	PUNCT
biomedich-1001	123	6	molecular	molecular	ADJ
biomedich-1001	123	7	dynamic	dynamic	ADJ
biomedich-1001	123	8	study	study	NOUN
biomedich-1001	123	9	of	of	ADP
biomedich-1001	123	10	java	java	PROPN
biomedich-1001	123	11	cardamom	cardamom	PROPN
biomedich-1001	123	12	(	(	PUNCT
biomedich-1001	123	13	wurfbania	wurfbania	PROPN
biomedich-1001	123	14	compacta	compacta	PROPN
biomedich-1001	123	15	)	)	PUNCT
biomedich-1001	123	16	…	…	PUNCT
biomedich-1001	123	17	1253	1253	NUM
biomedich-1001	123	18	table	table	NOUN
biomedich-1001	123	19	6	6	NUM
biomedich-1001	123	20	.	.	PUNCT
biomedich-1001	124	1	amino	amino	ADJ
biomedich-1001	124	2	acids	acid	NOUN
biomedich-1001	124	3	from	from	ADP
biomedich-1001	124	4	molecular	molecular	ADJ
biomedich-1001	124	5	dynamics	dynamic	NOUN
biomedich-1001	124	6	.	.	PUNCT
biomedich-1001	125	1	no	no	DET
biomedich-1001	125	2	compounda	compounda	NOUN
biomedich-1001	125	3	name	name	VERB
biomedich-1001	125	4	molecular	molecular	ADJ
biomedich-1001	125	5	dynamic	dynamic	ADJ
biomedich-1001	125	6	result	result	NOUN
biomedich-1001	125	7	1	1	NUM
biomedich-1001	125	8	5	5	NUM
biomedich-1001	125	9	-	-	NUM
biomedich-1001	125	10	hidroksi-3,7,4'-trimetoksiflavon	hidroksi-3,7,4'-trimetoksiflavon	PROPN
biomedich-1001	125	11	glu802	glu802	PROPN
biomedich-1001	125	12	,	,	PUNCT
biomedich-1001	125	13	ser876	ser876	NOUN
biomedich-1001	125	14	,	,	PUNCT
biomedich-1001	125	15	phe914	phe914	PROPN
biomedich-1001	125	16	,	,	PUNCT
biomedich-1001	125	17	arg880	arg880	PROPN
biomedich-1001	125	18	,	,	PUNCT
biomedich-1001	125	19	ala1079	ala1079	NOUN
biomedich-1001	125	20	,	,	PUNCT
biomedich-1001	125	21	ser1080	ser1080	NOUN
biomedich-1001	125	22	,	,	PUNCT
biomedich-1001	125	23	glu1261	glu1261	NOUN
biomedich-1001	125	24	2	2	NUM
biomedich-1001	125	25	kaempferol	kaempferol	NOUN
biomedich-1001	125	26	arg880	arg880	ADJ
biomedich-1001	125	27	,	,	PUNCT
biomedich-1001	125	28	ser1008	ser1008	NOUN
biomedich-1001	125	29	,	,	PUNCT
biomedich-1001	125	30	thr1010	thr1010	NOUN
biomedich-1001	125	31	,	,	PUNCT
biomedich-1001	125	32	val1011	val1011	NOUN
biomedich-1001	125	33	,	,	PUNCT
biomedich-1001	125	34	ala1078	ala1078	ADJ
biomedich-1001	125	35	,	,	PUNCT
biomedich-1001	125	36	ala1079	ala1079	PROPN
biomedich-1001	125	37	,	,	PUNCT
biomedich-1001	125	38	glu1261	glu1261	NOUN
biomedich-1001	125	39	3	3	NUM
biomedich-1001	125	40	allopurinol	allopurinol	NOUN
biomedich-1001	125	41	glu802	glu802	PROPN
biomedich-1001	125	42	,	,	PUNCT
biomedich-1001	125	43	ser876	ser876	NOUN
biomedich-1001	125	44	,	,	PUNCT
biomedich-1001	125	45	thr1010	thr1010	NOUN
biomedich-1001	125	46	,	,	PUNCT
biomedich-1001	125	47	val1011	val1011	NOUN
biomedich-1001	125	48	,	,	PUNCT
biomedich-1001	125	49	lys771	lys771	NOUN
biomedich-1001	125	50	,	,	PUNCT
biomedich-1001	125	51	ala1078	ala1078	VERB
biomedich-1001	125	52	discussion	discussion	NOUN
biomedich-1001	125	53	protein	protein	NOUN
biomedich-1001	125	54	preparation	preparation	NOUN
biomedich-1001	125	55	with	with	ADP
biomedich-1001	125	56	the	the	DET
biomedich-1001	125	57	aim	aim	NOUN
biomedich-1001	125	58	of	of	ADP
biomedich-1001	125	59	optimizing	optimize	VERB
biomedich-1001	125	60	ligandreceptor	ligandreceptor	NOUN
biomedich-1001	125	61	interactions	interaction	NOUN
biomedich-1001	125	62	by	by	ADP
biomedich-1001	125	63	separating	separate	VERB
biomedich-1001	125	64	water	water	NOUN
biomedich-1001	125	65	molecules	molecule	NOUN
biomedich-1001	125	66	and	and	CCONJ
biomedich-1001	125	67	standard	standard	ADJ
biomedich-1001	125	68	ligands	ligand	NOUN
biomedich-1001	125	69	from	from	ADP
biomedich-1001	125	70	the	the	DET
biomedich-1001	125	71	receptor	receptor	NOUN
biomedich-1001	125	72	.	.	PUNCT
biomedich-1001	126	1	this	this	DET
biomedich-1001	126	2	separation	separation	NOUN
biomedich-1001	126	3	of	of	ADP
biomedich-1001	126	4	water	water	NOUN
biomedich-1001	126	5	molecules	molecule	NOUN
biomedich-1001	126	6	is	be	AUX
biomedich-1001	126	7	performed	perform	VERB
biomedich-1001	126	8	to	to	PART
biomedich-1001	126	9	prevent	prevent	VERB
biomedich-1001	126	10	the	the	DET
biomedich-1001	126	11	formation	formation	NOUN
biomedich-1001	126	12	of	of	ADP
biomedich-1001	126	13	hydrogen	hydrogen	NOUN
biomedich-1001	126	14	bonds	bond	NOUN
biomedich-1001	126	15	between	between	ADP
biomedich-1001	126	16	the	the	DET
biomedich-1001	126	17	ligand	ligand	ADJ
biomedich-1001	126	18	and	and	CCONJ
biomedich-1001	126	19	water	water	NOUN
biomedich-1001	126	20	molecules	molecule	NOUN
biomedich-1001	126	21	.	.	PUNCT
biomedich-1001	127	1	if	if	SCONJ
biomedich-1001	127	2	the	the	DET
biomedich-1001	127	3	separation	separation	NOUN
biomedich-1001	127	4	of	of	ADP
biomedich-1001	127	5	water	water	NOUN
biomedich-1001	127	6	molecules	molecule	NOUN
biomedich-1001	127	7	is	be	AUX
biomedich-1001	127	8	not	not	PART
biomedich-1001	127	9	carried	carry	VERB
biomedich-1001	127	10	out	out	ADP
biomedich-1001	127	11	,	,	PUNCT
biomedich-1001	127	12	the	the	DET
biomedich-1001	127	13	binding	bind	VERB
biomedich-1001	127	14	process	process	NOUN
biomedich-1001	127	15	will	will	AUX
biomedich-1001	127	16	become	become	VERB
biomedich-1001	127	17	increasingly	increasingly	ADV
biomedich-1001	127	18	complex	complex	ADJ
biomedich-1001	127	19	,	,	PUNCT
biomedich-1001	127	20	resulting	result	VERB
biomedich-1001	127	21	in	in	ADP
biomedich-1001	127	22	longer	long	ADJ
biomedich-1001	127	23	time	time	NOUN
biomedich-1001	127	24	requirements	requirement	NOUN
biomedich-1001	127	25	and	and	CCONJ
biomedich-1001	127	26	the	the	DET
biomedich-1001	127	27	presence	presence	NOUN
biomedich-1001	127	28	of	of	ADP
biomedich-1001	127	29	one	one	NUM
biomedich-1001	127	30	ligand	ligand	NOUN
biomedich-1001	127	31	will	will	AUX
biomedich-1001	127	32	hinder	hinder	VERB
biomedich-1001	127	33	other	other	ADJ
biomedich-1001	127	34	ligands	ligand	NOUN
biomedich-1001	127	35	from	from	ADP
biomedich-1001	127	36	binding	bind	VERB
biomedich-1001	127	37	to	to	ADP
biomedich-1001	127	38	the	the	DET
biomedich-1001	127	39	active	active	ADJ
biomedich-1001	127	40	site	site	NOUN
biomedich-1001	127	41	.	.	PUNCT
biomedich-1001	128	1	separation	separation	NOUN
biomedich-1001	128	2	is	be	AUX
biomedich-1001	128	3	also	also	ADV
biomedich-1001	128	4	carried	carry	VERB
biomedich-1001	128	5	out	out	ADP
biomedich-1001	128	6	on	on	ADP
biomedich-1001	128	7	natural	natural	ADJ
biomedich-1001	128	8	ligands	ligand	NOUN
biomedich-1001	128	9	present	present	ADJ
biomedich-1001	128	10	on	on	ADP
biomedich-1001	128	11	the	the	DET
biomedich-1001	128	12	receptor	receptor	NOUN
biomedich-1001	128	13	to	to	PART
biomedich-1001	128	14	be	be	AUX
biomedich-1001	128	15	used	use	VERB
biomedich-1001	128	16	in	in	ADP
biomedich-1001	128	17	the	the	DET
biomedich-1001	128	18	docking	docking	NOUN
biomedich-1001	128	19	validation	validation	NOUN
biomedich-1001	128	20	process	process	NOUN
biomedich-1001	128	21	.	.	PUNCT
biomedich-1001	129	1	based	base	VERB
biomedich-1001	129	2	on	on	ADP
biomedich-1001	129	3	the	the	DET
biomedich-1001	129	4	visualization	visualization	NOUN
biomedich-1001	129	5	results	result	NOUN
biomedich-1001	129	6	in	in	ADP
biomedich-1001	129	7	figure	figure	NOUN
biomedich-1001	129	8	2	2	NUM
biomedich-1001	129	9	,	,	PUNCT
biomedich-1001	129	10	it	it	PRON
biomedich-1001	129	11	can	can	AUX
biomedich-1001	129	12	be	be	AUX
biomedich-1001	129	13	seen	see	VERB
biomedich-1001	129	14	that	that	SCONJ
biomedich-1001	129	15	the	the	DET
biomedich-1001	129	16	interaction	interaction	NOUN
biomedich-1001	129	17	of	of	ADP
biomedich-1001	129	18	the	the	DET
biomedich-1001	129	19	3nvw	3nvw	ADJ
biomedich-1001	129	20	receptor	receptor	NOUN
biomedich-1001	129	21	has	have	VERB
biomedich-1001	129	22	hydrogen	hydrogen	NOUN
biomedich-1001	129	23	bonds	bond	NOUN
biomedich-1001	129	24	with	with	ADP
biomedich-1001	129	25	the	the	DET
biomedich-1001	129	26	amino	amino	NOUN
biomedich-1001	129	27	acid	acid	NOUN
biomedich-1001	129	28	residues	residue	NOUN
biomedich-1001	129	29	arg880	arg880	ADJ
biomedich-1001	129	30	,	,	PUNCT
biomedich-1001	129	31	thr	thr	PROPN
biomedich-1001	129	32	1010	1010	NUM
biomedich-1001	129	33	,	,	PUNCT
biomedich-1001	129	34	and	and	CCONJ
biomedich-1001	129	35	glu	glu	PROPN
biomedich-1001	129	36	802	802	NUM
biomedich-1001	129	37	.	.	PUNCT
biomedich-1001	130	1	meanwhile	meanwhile	ADV
biomedich-1001	130	2	,	,	PUNCT
biomedich-1001	130	3	there	there	PRON
biomedich-1001	130	4	are	be	VERB
biomedich-1001	130	5	hydrophobic	hydrophobic	NOUN
biomedich-1001	130	6	bonds	bond	NOUN
biomedich-1001	130	7	with	with	ADP
biomedich-1001	130	8	the	the	DET
biomedich-1001	130	9	amino	amino	NOUN
biomedich-1001	130	10	acid	acid	NOUN
biomedich-1001	130	11	residues	residue	NOUN
biomedich-1001	130	12	phe914	phe914	PROPN
biomedich-1001	130	13	,	,	PUNCT
biomedich-1001	130	14	ala1078	ala1078	ADJ
biomedich-1001	130	15	,	,	PUNCT
biomedich-1001	130	16	ala1079	ala1079	PROPN
biomedich-1001	130	17	,	,	PUNCT
biomedich-1001	130	18	and	and	CCONJ
biomedich-1001	130	19	phe1009	phe1009	NOUN
biomedich-1001	130	20	.	.	PUNCT
biomedich-1001	131	1	based	base	VERB
biomedich-1001	131	2	on	on	ADP
biomedich-1001	131	3	the	the	DET
biomedich-1001	131	4	overlay	overlay	NOUN
biomedich-1001	131	5	results	result	NOUN
biomedich-1001	131	6	in	in	ADP
biomedich-1001	131	7	figure	figure	NOUN
biomedich-1001	131	8	3b	3b	NUM
biomedich-1001	131	9	,	,	PUNCT
biomedich-1001	131	10	it	it	PRON
biomedich-1001	131	11	can	can	AUX
biomedich-1001	131	12	be	be	AUX
biomedich-1001	131	13	seen	see	VERB
biomedich-1001	131	14	that	that	SCONJ
biomedich-1001	131	15	the	the	DET
biomedich-1001	131	16	position	position	NOUN
biomedich-1001	131	17	of	of	ADP
biomedich-1001	131	18	the	the	DET
biomedich-1001	131	19	natural	natural	ADJ
biomedich-1001	131	20	ligand	ligand	NOUN
biomedich-1001	131	21	from	from	ADP
biomedich-1001	131	22	redocking	redocking	NOUN
biomedich-1001	131	23	,	,	PUNCT
biomedich-1001	131	24	which	which	PRON
biomedich-1001	131	25	is	be	AUX
biomedich-1001	131	26	turquoise	turquoise	NOUN
biomedich-1001	131	27	in	in	ADP
biomedich-1001	131	28	color	color	NOUN
biomedich-1001	131	29	,	,	PUNCT
biomedich-1001	131	30	is	be	AUX
biomedich-1001	131	31	similar	similar	ADJ
biomedich-1001	131	32	to	to	ADP
biomedich-1001	131	33	the	the	DET
biomedich-1001	131	34	position	position	NOUN
biomedich-1001	131	35	of	of	ADP
biomedich-1001	131	36	the	the	DET
biomedich-1001	131	37	natural	natural	ADJ
biomedich-1001	131	38	ligand	ligand	NOUN
biomedich-1001	131	39	in	in	ADP
biomedich-1001	131	40	crystallography	crystallography	NOUN
biomedich-1001	131	41	,	,	PUNCT
biomedich-1001	131	42	which	which	PRON
biomedich-1001	131	43	is	be	AUX
biomedich-1001	131	44	red	red	ADJ
biomedich-1001	131	45	.	.	PUNCT
biomedich-1001	132	1	based	base	VERB
biomedich-1001	132	2	on	on	ADP
biomedich-1001	132	3	table	table	NOUN
biomedich-1001	132	4	2	2	NUM
biomedich-1001	132	5	,	,	PUNCT
biomedich-1001	132	6	it	it	PRON
biomedich-1001	132	7	can	can	AUX
biomedich-1001	132	8	be	be	AUX
biomedich-1001	132	9	seen	see	VERB
biomedich-1001	132	10	that	that	SCONJ
biomedich-1001	132	11	there	there	PRON
biomedich-1001	132	12	are	be	VERB
biomedich-1001	132	13	9	9	NUM
biomedich-1001	132	14	test	test	NOUN
biomedich-1001	132	15	compounds	compound	NOUN
biomedich-1001	132	16	that	that	PRON
biomedich-1001	132	17	passed	pass	VERB
biomedich-1001	132	18	the	the	DET
biomedich-1001	132	19	toxicity	toxicity	NOUN
biomedich-1001	132	20	test	test	NOUN
biomedich-1001	132	21	.	.	PUNCT
biomedich-1001	133	1	in	in	ADP
biomedich-1001	133	2	the	the	DET
biomedich-1001	133	3	ld50	ld50	PROPN
biomedich-1001	133	4	parameter	parameter	NOUN
biomedich-1001	133	5	,	,	PUNCT
biomedich-1001	133	6	all	all	DET
biomedich-1001	133	7	compounds	compound	NOUN
biomedich-1001	133	8	are	be	AUX
biomedich-1001	133	9	predicted	predict	VERB
biomedich-1001	133	10	to	to	PART
biomedich-1001	133	11	have	have	VERB
biomedich-1001	133	12	a	a	DET
biomedich-1001	133	13	high	high	ADJ
biomedich-1001	133	14	ld50	ld50	PROPN
biomedich-1001	133	15	value	value	NOUN
biomedich-1001	133	16	.	.	PUNCT
biomedich-1001	134	1	in	in	ADP
biomedich-1001	134	2	addition	addition	NOUN
biomedich-1001	134	3	,	,	PUNCT
biomedich-1001	134	4	for	for	ADP
biomedich-1001	134	5	the	the	DET
biomedich-1001	134	6	parameter	parameter	NOUN
biomedich-1001	134	7	of	of	ADP
biomedich-1001	134	8	hepatotoxicity	hepatotoxicity	NOUN
biomedich-1001	134	9	,	,	PUNCT
biomedich-1001	134	10	the	the	DET
biomedich-1001	134	11	compounds	compound	NOUN
biomedich-1001	134	12	are	be	AUX
biomedich-1001	134	13	not	not	PART
biomedich-1001	134	14	toxic	toxic	ADJ
biomedich-1001	134	15	to	to	ADP
biomedich-1001	134	16	the	the	DET
biomedich-1001	134	17	liver	liver	NOUN
biomedich-1001	134	18	.	.	PUNCT
biomedich-1001	135	1	furthermore	furthermore	ADV
biomedich-1001	135	2	,	,	PUNCT
biomedich-1001	135	3	9	9	NUM
biomedich-1001	135	4	test	test	NOUN
biomedich-1001	135	5	compounds	compound	NOUN
biomedich-1001	135	6	and	and	CCONJ
biomedich-1001	135	7	a	a	DET
biomedich-1001	135	8	comparator	comparator	NOUN
biomedich-1001	135	9	drug	drug	NOUN
biomedich-1001	135	10	that	that	PRON
biomedich-1001	135	11	passed	pass	VERB
biomedich-1001	135	12	the	the	DET
biomedich-1001	135	13	toxicity	toxicity	NOUN
biomedich-1001	135	14	test	test	NOUN
biomedich-1001	135	15	were	be	AUX
biomedich-1001	135	16	continued	continue	VERB
biomedich-1001	135	17	with	with	ADP
biomedich-1001	135	18	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	135	19	testing	testing	NOUN
biomedich-1001	135	20	.	.	PUNCT
biomedich-1001	136	1	protonation	protonation	NOUN
biomedich-1001	136	2	aims	aim	VERB
biomedich-1001	136	3	to	to	PART
biomedich-1001	136	4	adjust	adjust	VERB
biomedich-1001	136	5	the	the	DET
biomedich-1001	136	6	ph	ph	NOUN
biomedich-1001	136	7	of	of	ADP
biomedich-1001	136	8	the	the	DET
biomedich-1001	136	9	test	test	NOUN
biomedich-1001	136	10	compound	compound	NOUN
biomedich-1001	136	11	to	to	ADP
biomedich-1001	136	12	the	the	DET
biomedich-1001	136	13	physiological	physiological	ADJ
biomedich-1001	136	14	ph	ph	NOUN
biomedich-1001	136	15	of	of	ADP
biomedich-1001	136	16	the	the	DET
biomedich-1001	136	17	human	human	ADJ
biomedich-1001	136	18	body	body	NOUN
biomedich-1001	136	19	,	,	PUNCT
biomedich-1001	136	20	which	which	PRON
biomedich-1001	136	21	is	be	AUX
biomedich-1001	136	22	7.4	7.4	NUM
biomedich-1001	136	23	.	.	PUNCT
biomedich-1001	137	1	subsequently	subsequently	ADV
biomedich-1001	137	2	,	,	PUNCT
biomedich-1001	137	3	conformation	conformation	NOUN
biomedich-1001	137	4	is	be	AUX
biomedich-1001	137	5	carried	carry	VERB
biomedich-1001	137	6	out	out	ADP
biomedich-1001	137	7	to	to	PART
biomedich-1001	137	8	maintain	maintain	VERB
biomedich-1001	137	9	the	the	DET
biomedich-1001	137	10	position	position	NOUN
biomedich-1001	137	11	of	of	ADP
biomedich-1001	137	12	the	the	DET
biomedich-1001	137	13	most	most	ADV
biomedich-1001	137	14	stable	stable	ADJ
biomedich-1001	137	15	molecule	molecule	NOUN
biomedich-1001	137	16	when	when	SCONJ
biomedich-1001	137	17	interacting	interact	VERB
biomedich-1001	137	18	with	with	ADP
biomedich-1001	137	19	the	the	DET
biomedich-1001	137	20	active	active	ADJ
biomedich-1001	137	21	site	site	NOUN
biomedich-1001	137	22	of	of	ADP
biomedich-1001	137	23	the	the	DET
biomedich-1001	137	24	receptor	receptor	NOUN
biomedich-1001	137	25	.	.	PUNCT
biomedich-1001	138	1	toxicity	toxicity	NOUN
biomedich-1001	138	2	testing	testing	NOUN
biomedich-1001	138	3	on	on	ADP
biomedich-1001	138	4	test	test	NOUN
biomedich-1001	138	5	compounds	compound	NOUN
biomedich-1001	138	6	to	to	PART
biomedich-1001	138	7	observe	observe	VERB
biomedich-1001	138	8	the	the	DET
biomedich-1001	138	9	toxic	toxic	ADJ
biomedich-1001	138	10	effects	effect	NOUN
biomedich-1001	138	11	of	of	ADP
biomedich-1001	138	12	a	a	DET
biomedich-1001	138	13	substance	substance	NOUN
biomedich-1001	138	14	on	on	ADP
biomedich-1001	138	15	biological	biological	ADJ
biomedich-1001	138	16	systems	system	NOUN
biomedich-1001	138	17	.	.	PUNCT
biomedich-1001	139	1	in	in	ADP
biomedich-1001	139	2	the	the	DET
biomedich-1001	139	3	ld50	ld50	PROPN
biomedich-1001	139	4	parameter	parameter	NOUN
biomedich-1001	139	5	,	,	PUNCT
biomedich-1001	139	6	all	all	DET
biomedich-1001	139	7	compounds	compound	NOUN
biomedich-1001	139	8	are	be	AUX
biomedich-1001	139	9	predicted	predict	VERB
biomedich-1001	139	10	to	to	PART
biomedich-1001	139	11	have	have	VERB
biomedich-1001	139	12	high	high	ADJ
biomedich-1001	139	13	ld50	ld50	PROPN
biomedich-1001	139	14	values	value	NOUN
biomedich-1001	139	15	.	.	PUNCT
biomedich-1001	140	1	according	accord	VERB
biomedich-1001	140	2	to	to	ADP
biomedich-1001	140	3	(	(	PUNCT
biomedich-1001	140	4	thahara	thahara	NOUN
biomedich-1001	140	5	et	et	PROPN
biomedich-1001	140	6	al	al	PROPN
biomedich-1001	140	7	.	.	PROPN
biomedich-1001	140	8	,	,	PUNCT
biomedich-1001	140	9	2022	2022	NUM
biomedich-1001	140	10	)	)	PUNCT
biomedich-1001	140	11	,	,	PUNCT
biomedich-1001	140	12	the	the	PRON
biomedich-1001	140	13	higher	high	ADJ
biomedich-1001	140	14	the	the	DET
biomedich-1001	140	15	ld50	ld50	PROPN
biomedich-1001	140	16	value	value	NOUN
biomedich-1001	140	17	,	,	PUNCT
biomedich-1001	140	18	the	the	PRON
biomedich-1001	140	19	lower	low	ADJ
biomedich-1001	140	20	the	the	DET
biomedich-1001	140	21	toxicity	toxicity	NOUN
biomedich-1001	140	22	,	,	PUNCT
biomedich-1001	140	23	indicating	indicate	VERB
biomedich-1001	140	24	that	that	SCONJ
biomedich-1001	140	25	the	the	DET
biomedich-1001	140	26	compound	compound	NOUN
biomedich-1001	140	27	is	be	AUX
biomedich-1001	140	28	safe	safe	ADJ
biomedich-1001	140	29	.	.	PUNCT
biomedich-1001	141	1	in	in	ADP
biomedich-1001	141	2	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	141	3	testing	testing	NOUN
biomedich-1001	141	4	,	,	PUNCT
biomedich-1001	141	5	adme	adme	NOUN
biomedich-1001	141	6	(	(	PUNCT
biomedich-1001	141	7	absorption	absorption	NOUN
biomedich-1001	141	8	,	,	PUNCT
biomedich-1001	141	9	distribution	distribution	NOUN
biomedich-1001	141	10	,	,	PUNCT
biomedich-1001	141	11	metabolism	metabolism	NOUN
biomedich-1001	141	12	,	,	PUNCT
biomedich-1001	141	13	and	and	CCONJ
biomedich-1001	141	14	excretion	excretion	NOUN
biomedich-1001	141	15	)	)	PUNCT
biomedich-1001	141	16	was	be	AUX
biomedich-1001	141	17	analyzed	analyze	VERB
biomedich-1001	141	18	using	use	VERB
biomedich-1001	141	19	the	the	DET
biomedich-1001	141	20	website	website	NOUN
biomedich-1001	141	21	https://preadmet.webservice.bmdrc.org/.	https://preadmet.webservice.bmdrc.org/.	PUNCT
biomedich-1001	141	22	the	the	DET
biomedich-1001	141	23	parameters	parameter	NOUN
biomedich-1001	141	24	observed	observe	VERB
biomedich-1001	141	25	included	include	VERB
biomedich-1001	141	26	human	human	ADJ
biomedich-1001	141	27	colon	colon	NOUN
biomedich-1001	141	28	adenocarcinoma	adenocarcinoma	NOUN
biomedich-1001	141	29	(	(	PUNCT
biomedich-1001	141	30	caco2	caco2	NOUN
biomedich-1001	141	31	)	)	PUNCT
biomedich-1001	141	32	,	,	PUNCT
biomedich-1001	141	33	human	human	ADJ
biomedich-1001	141	34	intestinal	intestinal	ADJ
biomedich-1001	141	35	absorption	absorption	NOUN
biomedich-1001	141	36	(	(	PUNCT
biomedich-1001	141	37	hia	hia	PROPN
biomedich-1001	141	38	)	)	PUNCT
biomedich-1001	141	39	,	,	PUNCT
biomedich-1001	141	40	and	and	CCONJ
biomedich-1001	141	41	plasma	plasma	NOUN
biomedich-1001	141	42	protein	protein	NOUN
biomedich-1001	141	43	binding	bind	VERB
biomedich-1001	141	44	(	(	PUNCT
biomedich-1001	141	45	ppb	ppb	NOUN
biomedich-1001	141	46	)	)	PUNCT
biomedich-1001	141	47	.	.	PUNCT
biomedich-1001	142	1	the	the	DET
biomedich-1001	142	2	results	result	NOUN
biomedich-1001	142	3	of	of	ADP
biomedich-1001	142	4	the	the	DET
biomedich-1001	142	5	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	142	6	testing	testing	NOUN
biomedich-1001	142	7	can	can	AUX
biomedich-1001	142	8	be	be	AUX
biomedich-1001	142	9	seen	see	VERB
biomedich-1001	142	10	in	in	ADP
biomedich-1001	142	11	table	table	NOUN
biomedich-1001	142	12	2	2	NUM
biomedich-1001	142	13	wich	wich	PRON
biomedich-1001	142	14	states	state	VERB
biomedich-1001	142	15	that	that	SCONJ
biomedich-1001	142	16	all	all	DET
biomedich-1001	142	17	test	test	NOUN
biomedich-1001	142	18	compounds	compound	NOUN
biomedich-1001	142	19	have	have	VERB
biomedich-1001	142	20	moderate	moderate	ADJ
biomedich-1001	142	21	permeability	permeability	NOUN
biomedich-1001	142	22	or	or	CCONJ
biomedich-1001	142	23	the	the	DET
biomedich-1001	142	24	ability	ability	NOUN
biomedich-1001	142	25	to	to	PART
biomedich-1001	142	26	penetrate	penetrate	VERB
biomedich-1001	142	27	the	the	DET
biomedich-1001	142	28	intestinal	intestinal	ADJ
biomedich-1001	142	29	epithelial	epithelial	ADJ
biomedich-1001	142	30	cell	cell	NOUN
biomedich-1001	142	31	barrier	barrier	NOUN
biomedich-1001	142	32	moderately	moderately	ADV
biomedich-1001	142	33	,	,	PUNCT
biomedich-1001	142	34	has	have	VERB
biomedich-1001	142	35	an	an	DET
biomedich-1001	142	36	hia	hia	PROPN
biomedich-1001	142	37	value	value	NOUN
biomedich-1001	142	38	between	between	ADP
biomedich-1001	142	39	70	70	NUM
biomedich-1001	142	40	-	-	SYM
biomedich-1001	142	41	100	100	NUM
biomedich-1001	142	42	%	%	NOUN
biomedich-1001	142	43	which	which	PRON
biomedich-1001	142	44	means	mean	VERB
biomedich-1001	142	45	it	it	PRON
biomedich-1001	142	46	has	have	VERB
biomedich-1001	142	47	a	a	DET
biomedich-1001	142	48	high	high	ADJ
biomedich-1001	142	49	absorption	absorption	NOUN
biomedich-1001	142	50	capability	capability	NOUN
biomedich-1001	142	51	,	,	PUNCT
biomedich-1001	142	52	a	a	DET
biomedich-1001	142	53	ppb	ppb	NOUN
biomedich-1001	142	54	value	value	NOUN
biomedich-1001	142	55	>	>	X
biomedich-1001	142	56	90	90	NUM
biomedich-1001	142	57	%	%	NOUN
biomedich-1001	142	58	indicates	indicate	VERB
biomedich-1001	142	59	an	an	DET
biomedich-1001	142	60	inactive	inactive	ADJ
biomedich-1001	142	61	nature	nature	NOUN
biomedich-1001	142	62	.	.	PUNCT
biomedich-1001	143	1	meanwhile	meanwhile	ADV
biomedich-1001	143	2	,	,	PUNCT
biomedich-1001	143	3	the	the	DET
biomedich-1001	143	4	other	other	ADJ
biomedich-1001	143	5	3	3	NUM
biomedich-1001	143	6	test	test	NOUN
biomedich-1001	143	7	compounds	compound	NOUN
biomedich-1001	143	8	have	have	VERB
biomedich-1001	143	9	values	value	NOUN
biomedich-1001	143	10	<	<	X
biomedich-1001	143	11	90	90	NUM
biomedich-1001	143	12	%	%	NOUN
biomedich-1001	143	13	,	,	PUNCT
biomedich-1001	143	14	which	which	PRON
biomedich-1001	143	15	means	mean	VERB
biomedich-1001	143	16	they	they	PRON
biomedich-1001	143	17	are	be	AUX
biomedich-1001	143	18	loosely	loosely	ADV
biomedich-1001	143	19	bound	bind	VERB
biomedich-1001	143	20	to	to	ADP
biomedich-1001	143	21	plasma	plasma	NOUN
biomedich-1001	143	22	proteins	protein	NOUN
biomedich-1001	143	23	,	,	PUNCT
biomedich-1001	143	24	allowing	allow	VERB
biomedich-1001	143	25	them	they	PRON
biomedich-1001	143	26	to	to	PART
biomedich-1001	143	27	act	act	VERB
biomedich-1001	143	28	on	on	ADP
biomedich-1001	143	29	the	the	DET
biomedich-1001	143	30	target	target	NOUN
biomedich-1001	143	31	and	and	CCONJ
biomedich-1001	143	32	produce	produce	VERB
biomedich-1001	143	33	a	a	DET
biomedich-1001	143	34	biological	biological	ADJ
biomedich-1001	143	35	response	response	NOUN
biomedich-1001	143	36	.	.	PUNCT
biomedich-1001	144	1	human	human	ADJ
biomedich-1001	144	2	colon	colon	NOUN
biomedich-1001	144	3	adenocarcinoma	adenocarcinoma	NOUN
biomedich-1001	144	4	(	(	PUNCT
biomedich-1001	144	5	caco-2	caco-2	NOUN
biomedich-1001	144	6	)	)	PUNCT
biomedich-1001	144	7	is	be	AUX
biomedich-1001	144	8	a	a	DET
biomedich-1001	144	9	parameter	parameter	NOUN
biomedich-1001	144	10	that	that	PRON
biomedich-1001	144	11	indicates	indicate	VERB
biomedich-1001	144	12	permeability	permeability	NOUN
biomedich-1001	144	13	capability	capability	NOUN
biomedich-1001	144	14	used	use	VERB
biomedich-1001	144	15	to	to	PART
biomedich-1001	144	16	determine	determine	VERB
biomedich-1001	144	17	the	the	DET
biomedich-1001	144	18	transfer	transfer	NOUN
biomedich-1001	144	19	of	of	ADP
biomedich-1001	144	20	drugs	drug	NOUN
biomedich-1001	144	21	through	through	ADP
biomedich-1001	144	22	intestinal	intestinal	ADJ
biomedich-1001	144	23	epithelial	epithelial	ADJ
biomedich-1001	144	24	cells	cell	NOUN
biomedich-1001	144	25	derived	derive	VERB
biomedich-1001	144	26	from	from	ADP
biomedich-1001	144	27	human	human	ADJ
biomedich-1001	144	28	colorectal	colorectal	ADJ
biomedich-1001	144	29	adenocarcinoma	adenocarcinoma	NOUN
biomedich-1001	144	30	with	with	ADP
biomedich-1001	144	31	dual	dual	ADJ
biomedich-1001	144	32	transport	transport	NOUN
biomedich-1001	144	33	pathways	pathway	NOUN
biomedich-1001	144	34	in	in	ADP
biomedich-1001	144	35	vitro	vitro	X
biomedich-1001	144	36	(	(	PUNCT
biomedich-1001	144	37	chintha	chintha	INTJ
biomedich-1001	144	38	et	et	PROPN
biomedich-1001	144	39	al	al	PROPN
biomedich-1001	144	40	.	.	PROPN
biomedich-1001	144	41	,	,	PUNCT
biomedich-1001	144	42	2020	2020	NUM
biomedich-1001	144	43	)	)	PUNCT
biomedich-1001	144	44	.	.	PUNCT
biomedich-1001	145	1	based	base	VERB
biomedich-1001	145	2	on	on	ADP
biomedich-1001	145	3	table	table	NOUN
biomedich-1001	145	4	2	2	NUM
biomedich-1001	145	5	,	,	PUNCT
biomedich-1001	145	6	it	it	PRON
biomedich-1001	145	7	can	can	AUX
biomedich-1001	145	8	be	be	AUX
biomedich-1001	145	9	seen	see	VERB
biomedich-1001	145	10	that	that	SCONJ
biomedich-1001	145	11	all	all	DET
biomedich-1001	145	12	test	test	NOUN
biomedich-1001	145	13	compounds	compound	NOUN
biomedich-1001	145	14	have	have	VERB
biomedich-1001	145	15	moderate	moderate	ADJ
biomedich-1001	145	16	permeability	permeability	NOUN
biomedich-1001	145	17	or	or	CCONJ
biomedich-1001	145	18	the	the	DET
biomedich-1001	145	19	ability	ability	NOUN
biomedich-1001	145	20	to	to	PART
biomedich-1001	145	21	penetrate	penetrate	VERB
biomedich-1001	145	22	the	the	DET
biomedich-1001	145	23	intestinal	intestinal	ADJ
biomedich-1001	145	24	epithelial	epithelial	ADJ
biomedich-1001	145	25	cell	cell	NOUN
biomedich-1001	145	26	barrier	barrier	NOUN
biomedich-1001	145	27	moderately	moderately	ADV
biomedich-1001	145	28	.	.	PUNCT
biomedich-1001	146	1	the	the	DET
biomedich-1001	146	2	administration	administration	NOUN
biomedich-1001	146	3	of	of	ADP
biomedich-1001	146	4	drugs	drug	NOUN
biomedich-1001	146	5	can	can	AUX
biomedich-1001	146	6	be	be	AUX
biomedich-1001	146	7	challenging	challenge	VERB
biomedich-1001	146	8	because	because	SCONJ
biomedich-1001	146	9	the	the	DET
biomedich-1001	146	10	human	human	ADJ
biomedich-1001	146	11	digestive	digestive	ADJ
biomedich-1001	146	12	tract	tract	NOUN
biomedich-1001	146	13	is	be	AUX
biomedich-1001	146	14	very	very	ADV
biomedich-1001	146	15	complex	complex	ADJ
biomedich-1001	146	16	and	and	CCONJ
biomedich-1001	146	17	has	have	VERB
biomedich-1001	146	18	a	a	DET
biomedich-1001	146	19	number	number	NOUN
biomedich-1001	146	20	of	of	ADP
biomedich-1001	146	21	physiological	physiological	ADJ
biomedich-1001	146	22	barriers	barrier	NOUN
biomedich-1001	146	23	that	that	PRON
biomedich-1001	146	24	affect	affect	VERB
biomedich-1001	146	25	drug	drug	NOUN
biomedich-1001	146	26	delivery	delivery	NOUN
biomedich-1001	146	27	.	.	PUNCT
biomedich-1001	147	1	these	these	DET
biomedich-1001	147	2	challenges	challenge	NOUN
biomedich-1001	147	3	include	include	VERB
biomedich-1001	147	4	poor	poor	ADJ
biomedich-1001	147	5	drug	drug	NOUN
biomedich-1001	147	6	solubility	solubility	NOUN
biomedich-1001	147	7	,	,	PUNCT
biomedich-1001	147	8	poor	poor	ADJ
biomedich-1001	147	9	drug	drug	NOUN
biomedich-1001	147	10	stability	stability	NOUN
biomedich-1001	147	11	,	,	PUNCT
biomedich-1001	147	12	and	and	CCONJ
biomedich-1001	147	13	low	low	ADJ
biomedich-1001	147	14	drug	drug	NOUN
biomedich-1001	147	15	permeability	permeability	NOUN
biomedich-1001	147	16	across	across	ADP
biomedich-1001	147	17	the	the	DET
biomedich-1001	147	18	mucosal	mucosal	NOUN
biomedich-1001	147	19	barrier	barrier	NOUN
biomedich-1001	147	20	(	(	PUNCT
biomedich-1001	147	21	pasaribu	pasaribu	PROPN
biomedich-1001	147	22	,	,	PUNCT
biomedich-1001	147	23	2024	2024	NUM
biomedich-1001	147	24	)	)	PUNCT
biomedich-1001	147	25	.	.	PUNCT
biomedich-1001	148	1	the	the	DET
biomedich-1001	148	2	human	human	ADJ
biomedich-1001	148	3	intestinal	intestinal	ADJ
biomedich-1001	148	4	absorption	absorption	NOUN
biomedich-1001	148	5	(	(	PUNCT
biomedich-1001	148	6	hia	hia	PROPN
biomedich-1001	148	7	)	)	PUNCT
biomedich-1001	148	8	parameter	parameter	NOUN
biomedich-1001	148	9	is	be	AUX
biomedich-1001	148	10	used	use	VERB
biomedich-1001	148	11	to	to	PART
biomedich-1001	148	12	predict	predict	VERB
biomedich-1001	148	13	the	the	DET
biomedich-1001	148	14	drug	drug	NOUN
biomedich-1001	148	15	absorption	absorption	NOUN
biomedich-1001	148	16	process	process	NOUN
biomedich-1001	148	17	in	in	ADP
biomedich-1001	148	18	the	the	DET
biomedich-1001	148	19	intestine	intestine	NOUN
biomedich-1001	148	20	by	by	ADP
biomedich-1001	148	21	looking	look	VERB
biomedich-1001	148	22	at	at	ADP
biomedich-1001	148	23	the	the	DET
biomedich-1001	148	24	results	result	NOUN
biomedich-1001	148	25	of	of	ADP
biomedich-1001	148	26	adding	add	VERB
biomedich-1001	148	27	bioavailability	bioavailability	NOUN
biomedich-1001	148	28	to	to	ADP
biomedich-1001	148	29	absorption	absorption	NOUN
biomedich-1001	148	30	,	,	PUNCT
biomedich-1001	148	31	which	which	PRON
biomedich-1001	148	32	is	be	AUX
biomedich-1001	148	33	evaluated	evaluate	VERB
biomedich-1001	148	34	from	from	ADP
biomedich-1001	148	35	the	the	DET
biomedich-1001	148	36	excretion	excretion	NOUN
biomedich-1001	148	37	ratio	ratio	NOUN
biomedich-1001	148	38	through	through	ADP
biomedich-1001	148	39	bile	bile	NOUN
biomedich-1001	148	40	,	,	PUNCT
biomedich-1001	148	41	feces	fece	NOUN
biomedich-1001	148	42	,	,	PUNCT
biomedich-1001	148	43	and	and	CCONJ
biomedich-1001	148	44	urine	urine	NOUN
biomedich-1001	148	45	(	(	PUNCT
biomedich-1001	148	46	monikasari	monikasari	PROPN
biomedich-1001	148	47	et	et	PROPN
biomedich-1001	148	48	al	al	PROPN
biomedich-1001	148	49	.	.	PROPN
biomedich-1001	148	50	,	,	PUNCT
biomedich-1001	148	51	2023	2023	NUM
biomedich-1001	148	52	)	)	PUNCT
biomedich-1001	148	53	.	.	PUNCT
biomedich-1001	149	1	based	base	VERB
biomedich-1001	149	2	on	on	ADP
biomedich-1001	149	3	table	table	NOUN
biomedich-1001	149	4	3	3	NUM
biomedich-1001	149	5	,	,	PUNCT
biomedich-1001	149	6	it	it	PRON
biomedich-1001	149	7	can	can	AUX
biomedich-1001	149	8	be	be	AUX
biomedich-1001	149	9	seen	see	VERB
biomedich-1001	149	10	that	that	SCONJ
biomedich-1001	149	11	all	all	DET
biomedich-1001	149	12	test	test	NOUN
biomedich-1001	149	13	compounds	compound	NOUN
biomedich-1001	149	14	have	have	VERB
biomedich-1001	149	15	hia	hia	PROPN
biomedich-1001	149	16	values	value	NOUN
biomedich-1001	149	17	between	between	ADP
biomedich-1001	149	18	70	70	NUM
biomedich-1001	149	19	-	-	SYM
biomedich-1001	149	20	100	100	NUM
biomedich-1001	149	21	%	%	NOUN
biomedich-1001	149	22	,	,	PUNCT
biomedich-1001	149	23	which	which	PRON
biomedich-1001	149	24	means	mean	VERB
biomedich-1001	149	25	they	they	PRON
biomedich-1001	149	26	have	have	VERB
biomedich-1001	149	27	high	high	ADJ
biomedich-1001	149	28	absorption	absorption	NOUN
biomedich-1001	149	29	capacity	capacity	NOUN
biomedich-1001	149	30	.	.	PUNCT
biomedich-1001	150	1	the	the	DET
biomedich-1001	150	2	plasma	plasma	NOUN
biomedich-1001	150	3	protein	protein	NOUN
biomedich-1001	150	4	binding	bind	VERB
biomedich-1001	150	5	(	(	PUNCT
biomedich-1001	150	6	ppb	ppb	NOUN
biomedich-1001	150	7	)	)	PUNCT
biomedich-1001	150	8	parameter	parameter	NOUN
biomedich-1001	150	9	shows	show	VERB
biomedich-1001	150	10	the	the	DET
biomedich-1001	150	11	ability	ability	NOUN
biomedich-1001	150	12	of	of	ADP
biomedich-1001	150	13	compounds	compound	NOUN
biomedich-1001	150	14	to	to	PART
biomedich-1001	150	15	bind	bind	VERB
biomedich-1001	150	16	to	to	ADP
biomedich-1001	150	17	plasma	plasma	NOUN
biomedich-1001	150	18	proteins	protein	NOUN
biomedich-1001	150	19	.	.	PUNCT
biomedich-1001	151	1	compounds	compound	NOUN
biomedich-1001	151	2	that	that	PRON
biomedich-1001	151	3	are	be	AUX
biomedich-1001	151	4	strongly	strongly	ADV
biomedich-1001	151	5	bound	bind	VERB
biomedich-1001	151	6	to	to	ADP
biomedich-1001	151	7	plasma	plasma	NOUN
biomedich-1001	151	8	proteins	protein	NOUN
biomedich-1001	151	9	will	will	AUX
biomedich-1001	151	10	be	be	AUX
biomedich-1001	151	11	inactive	inactive	ADJ
biomedich-1001	151	12	;	;	PUNCT
biomedich-1001	151	13	only	only	ADV
biomedich-1001	151	14	free	free	ADJ
biomedich-1001	151	15	and	and	CCONJ
biomedich-1001	151	16	unbound	unbound	NOUN
biomedich-1001	151	17	drugs	drug	NOUN
biomedich-1001	151	18	(	(	PUNCT
biomedich-1001	151	19	free	free	ADJ
biomedich-1001	151	20	-	-	PUNCT
biomedich-1001	151	21	bound	bind	VERB
biomedich-1001	151	22	)	)	PUNCT
biomedich-1001	151	23	can	can	AUX
biomedich-1001	151	24	act	act	VERB
biomedich-1001	151	25	on	on	ADP
biomedich-1001	151	26	targets	target	NOUN
biomedich-1001	151	27	,	,	PUNCT
biomedich-1001	151	28	resulting	result	VERB
biomedich-1001	151	29	in	in	ADP
biomedich-1001	151	30	a	a	DET
biomedich-1001	151	31	biological	biological	ADJ
biomedich-1001	151	32	response	response	NOUN
biomedich-1001	151	33	and	and	CCONJ
biomedich-1001	151	34	can	can	AUX
biomedich-1001	151	35	enter	enter	VERB
biomedich-1001	151	36	the	the	DET
biomedich-1001	151	37	elimination	elimination	NOUN
biomedich-1001	151	38	process	process	NOUN
biomedich-1001	151	39	(	(	PUNCT
biomedich-1001	151	40	rahmawaty	rahmawaty	NOUN
biomedich-1001	151	41	et	et	PROPN
biomedich-1001	151	42	al	al	PROPN
biomedich-1001	151	43	.	.	PROPN
biomedich-1001	151	44	,	,	PUNCT
biomedich-1001	151	45	2022	2022	NUM
biomedich-1001	151	46	)	)	PUNCT
biomedich-1001	151	47	.	.	PUNCT
biomedich-1001	152	1	as	as	SCONJ
biomedich-1001	152	2	seen	see	VERB
biomedich-1001	152	3	in	in	ADP
biomedich-1001	152	4	table	table	NOUN
biomedich-1001	152	5	2	2	NUM
biomedich-1001	152	6	,	,	PUNCT
biomedich-1001	152	7	6	6	NUM
biomedich-1001	152	8	compounds	compound	NOUN
biomedich-1001	152	9	have	have	VERB
biomedich-1001	152	10	ppb	ppb	NOUN
biomedich-1001	152	11	values	value	NOUN
biomedich-1001	152	12	>	>	X
biomedich-1001	152	13	90	90	NUM
biomedich-1001	152	14	%	%	NOUN
biomedich-1001	152	15	,	,	PUNCT
biomedich-1001	152	16	meaning	mean	VERB
biomedich-1001	152	17	they	they	PRON
biomedich-1001	152	18	are	be	AUX
biomedich-1001	152	19	inactive	inactive	ADJ
biomedich-1001	152	20	.	.	PUNCT
biomedich-1001	153	1	in	in	ADP
biomedich-1001	153	2	contrast	contrast	NOUN
biomedich-1001	153	3	,	,	PUNCT
biomedich-1001	153	4	the	the	DET
biomedich-1001	153	5	other	other	ADJ
biomedich-1001	153	6	3	3	NUM
biomedich-1001	153	7	test	test	NOUN
biomedich-1001	153	8	compounds	compound	NOUN
biomedich-1001	153	9	have	have	VERB
biomedich-1001	153	10	values	value	NOUN
biomedich-1001	153	11	<	<	X
biomedich-1001	153	12	90	90	NUM
biomedich-1001	153	13	%	%	NOUN
biomedich-1001	153	14	,	,	PUNCT
biomedich-1001	153	15	which	which	PRON
biomedich-1001	153	16	means	mean	VERB
biomedich-1001	153	17	they	they	PRON
biomedich-1001	153	18	are	be	AUX
biomedich-1001	153	19	free	free	ADV
biomedich-1001	153	20	-	-	PUNCT
biomedich-1001	153	21	bound	bind	VERB
biomedich-1001	153	22	to	to	ADP
biomedich-1001	153	23	plasma	plasma	NOUN
biomedich-1001	153	24	proteins	protein	NOUN
biomedich-1001	153	25	,	,	PUNCT
biomedich-1001	153	26	allowing	allow	VERB
biomedich-1001	153	27	them	they	PRON
biomedich-1001	153	28	to	to	PART
biomedich-1001	153	29	act	act	VERB
biomedich-1001	153	30	on	on	ADP
biomedich-1001	153	31	targets	target	NOUN
biomedich-1001	153	32	and	and	CCONJ
biomedich-1001	153	33	produce	produce	VERB
biomedich-1001	153	34	a	a	DET
biomedich-1001	153	35	response	response	NOUN
biomedich-1001	153	36	.	.	PUNCT
biomedich-1001	154	1	from	from	ADP
biomedich-1001	154	2	the	the	DET
biomedich-1001	154	3	analysis	analysis	NOUN
biomedich-1001	154	4	of	of	ADP
biomedich-1001	154	5	these	these	DET
biomedich-1001	154	6	three	three	NUM
biomedich-1001	154	7	parameters	parameter	NOUN
biomedich-1001	154	8	,	,	PUNCT
biomedich-1001	154	9	it	it	PRON
biomedich-1001	154	10	can	can	AUX
biomedich-1001	154	11	be	be	AUX
biomedich-1001	154	12	concluded	conclude	VERB
biomedich-1001	154	13	that	that	SCONJ
biomedich-1001	154	14	the	the	DET
biomedich-1001	154	15	3	3	NUM
biomedich-1001	154	16	test	test	NOUN
biomedich-1001	154	17	compounds	compound	NOUN
biomedich-1001	154	18	have	have	VERB
biomedich-1001	154	19	good	good	ADJ
biomedich-1001	154	20	pharmacokinetic	pharmacokinetic	ADJ
biomedich-1001	154	21	properties	property	NOUN
biomedich-1001	154	22	in	in	ADP
biomedich-1001	154	23	the	the	DET
biomedich-1001	154	24	body	body	NOUN
biomedich-1001	154	25	.	.	PUNCT
biomedich-1001	155	1	the	the	DET
biomedich-1001	155	2	molecular	molecular	ADJ
biomedich-1001	155	3	weight	weight	NOUN
biomedich-1001	155	4	parameter	parameter	NOUN
biomedich-1001	155	5	relates	relate	VERB
biomedich-1001	155	6	to	to	ADP
biomedich-1001	155	7	the	the	DET
biomedich-1001	155	8	ability	ability	NOUN
biomedich-1001	155	9	of	of	ADP
biomedich-1001	155	10	a	a	DET
biomedich-1001	155	11	compound	compound	NOUN
biomedich-1001	155	12	to	to	PART
biomedich-1001	155	13	cross	cross	VERB
biomedich-1001	155	14	biological	biological	ADJ
biomedich-1001	155	15	membranes	membrane	NOUN
biomedich-1001	155	16	during	during	ADP
biomedich-1001	155	17	the	the	DET
biomedich-1001	155	18	distribution	distribution	NOUN
biomedich-1001	155	19	process	process	NOUN
biomedich-1001	155	20	.	.	PUNCT
biomedich-1001	156	1	compounds	compound	NOUN
biomedich-1001	156	2	with	with	ADP
biomedich-1001	156	3	a	a	DET
biomedich-1001	156	4	molecular	molecular	ADJ
biomedich-1001	156	5	1254	1254	NUM
biomedich-1001	156	6	biology	biology	NOUN
biomedich-1001	156	7	,	,	PUNCT
biomedich-1001	156	8	medicine	medicine	NOUN
biomedich-1001	156	9	,	,	PUNCT
biomedich-1001	156	10	&	&	CCONJ
biomedich-1001	156	11	natural	natural	ADJ
biomedich-1001	156	12	product	product	NOUN
biomedich-1001	156	13	chemistry	chemistry	NOUN
biomedich-1001	156	14	14	14	NUM
biomedich-1001	156	15	(	(	PUNCT
biomedich-1001	156	16	2	2	NUM
biomedich-1001	156	17	)	)	PUNCT
biomedich-1001	156	18	,	,	PUNCT
biomedich-1001	156	19	2025	2025	NUM
biomedich-1001	156	20	:	:	PUNCT
biomedich-1001	156	21	1247	1247	NUM
biomedich-1001	156	22	-	-	SYM
biomedich-1001	156	23	1256	1256	NUM
biomedich-1001	156	24	weight	weight	NOUN
biomedich-1001	156	25	<	<	X
biomedich-1001	156	26	500	500	NUM
biomedich-1001	156	27	g	g	NOUN
biomedich-1001	156	28	/	/	SYM
biomedich-1001	156	29	mol	mol	NOUN
biomedich-1001	156	30	can	can	AUX
biomedich-1001	156	31	easily	easily	ADV
biomedich-1001	156	32	penetrate	penetrate	VERB
biomedich-1001	156	33	biological	biological	ADJ
biomedich-1001	156	34	membranes	membrane	NOUN
biomedich-1001	156	35	,	,	PUNCT
biomedich-1001	156	36	while	while	SCONJ
biomedich-1001	156	37	compounds	compound	NOUN
biomedich-1001	156	38	with	with	ADP
biomedich-1001	156	39	a	a	DET
biomedich-1001	156	40	molecular	molecular	ADJ
biomedich-1001	156	41	weight	weight	NOUN
biomedich-1001	156	42	>	>	PUNCT
biomedich-1001	156	43	500	500	NUM
biomedich-1001	156	44	g	g	NOUN
biomedich-1001	156	45	/	/	SYM
biomedich-1001	156	46	mol	mol	NOUN
biomedich-1001	156	47	will	will	AUX
biomedich-1001	156	48	have	have	VERB
biomedich-1001	156	49	difficulty	difficulty	NOUN
biomedich-1001	156	50	crossing	cross	VERB
biomedich-1001	156	51	the	the	DET
biomedich-1001	156	52	cell	cell	NOUN
biomedich-1001	156	53	membrane	membrane	NOUN
biomedich-1001	156	54	,	,	PUNCT
biomedich-1001	156	55	thereby	thereby	ADV
biomedich-1001	156	56	hindering	hinder	VERB
biomedich-1001	156	57	the	the	DET
biomedich-1001	156	58	distribution	distribution	NOUN
biomedich-1001	156	59	process	process	NOUN
biomedich-1001	156	60	.	.	PUNCT
biomedich-1001	157	1	the	the	DET
biomedich-1001	157	2	log	log	NOUN
biomedich-1001	157	3	p	p	NOUN
biomedich-1001	157	4	parameter	parameter	NOUN
biomedich-1001	157	5	or	or	CCONJ
biomedich-1001	157	6	logarithm	logarithm	NOUN
biomedich-1001	157	7	of	of	ADP
biomedich-1001	157	8	the	the	DET
biomedich-1001	157	9	partition	partition	NOUN
biomedich-1001	157	10	coefficient	coefficient	NOUN
biomedich-1001	157	11	indicates	indicate	VERB
biomedich-1001	157	12	a	a	DET
biomedich-1001	157	13	compound	compound	NOUN
biomedich-1001	157	14	's	's	PART
biomedich-1001	157	15	ability	ability	NOUN
biomedich-1001	157	16	to	to	PART
biomedich-1001	157	17	dissolve	dissolve	VERB
biomedich-1001	157	18	in	in	ADP
biomedich-1001	157	19	biological	biological	ADJ
biomedich-1001	157	20	fluids	fluid	NOUN
biomedich-1001	157	21	.	.	PUNCT
biomedich-1001	158	1	a	a	DET
biomedich-1001	158	2	good	good	ADJ
biomedich-1001	158	3	log	log	NOUN
biomedich-1001	158	4	p	p	NOUN
biomedich-1001	158	5	value	value	NOUN
biomedich-1001	158	6	is	be	AUX
biomedich-1001	158	7	less	less	ADJ
biomedich-1001	158	8	than	than	ADP
biomedich-1001	158	9	5	5	NUM
biomedich-1001	158	10	,	,	PUNCT
biomedich-1001	158	11	as	as	SCONJ
biomedich-1001	158	12	higher	high	ADJ
biomedich-1001	158	13	log	log	NOUN
biomedich-1001	158	14	p	p	NOUN
biomedich-1001	158	15	values	value	NOUN
biomedich-1001	158	16	indicate	indicate	VERB
biomedich-1001	158	17	greater	great	ADJ
biomedich-1001	158	18	hydrophobicity	hydrophobicity	NOUN
biomedich-1001	158	19	in	in	ADP
biomedich-1001	158	20	the	the	DET
biomedich-1001	158	21	compound	compound	NOUN
biomedich-1001	158	22	.	.	PUNCT
biomedich-1001	159	1	hydrophobic	hydrophobic	NOUN
biomedich-1001	159	2	compounds	compound	NOUN
biomedich-1001	159	3	are	be	AUX
biomedich-1001	159	4	typically	typically	ADV
biomedich-1001	159	5	more	more	ADV
biomedich-1001	159	6	toxic	toxic	ADJ
biomedich-1001	159	7	because	because	SCONJ
biomedich-1001	159	8	they	they	PRON
biomedich-1001	159	9	stay	stay	VERB
biomedich-1001	159	10	longer	long	ADV
biomedich-1001	159	11	in	in	ADP
biomedich-1001	159	12	the	the	DET
biomedich-1001	159	13	lipid	lipid	NOUN
biomedich-1001	159	14	bilayer	bilayer	NOUN
biomedich-1001	159	15	and	and	CCONJ
biomedich-1001	159	16	spread	spread	VERB
biomedich-1001	159	17	throughout	throughout	ADP
biomedich-1001	159	18	the	the	DET
biomedich-1001	159	19	body	body	NOUN
biomedich-1001	159	20	,	,	PUNCT
biomedich-1001	159	21	which	which	PRON
biomedich-1001	159	22	reduces	reduce	VERB
biomedich-1001	159	23	their	their	PRON
biomedich-1001	159	24	ability	ability	NOUN
biomedich-1001	159	25	to	to	PART
biomedich-1001	159	26	specifically	specifically	ADV
biomedich-1001	159	27	bind	bind	VERB
biomedich-1001	159	28	to	to	ADP
biomedich-1001	159	29	the	the	DET
biomedich-1001	159	30	intended	intend	VERB
biomedich-1001	159	31	target	target	NOUN
biomedich-1001	159	32	enzyme	enzyme	NOUN
biomedich-1001	159	33	.	.	PUNCT
biomedich-1001	160	1	on	on	ADP
biomedich-1001	160	2	the	the	DET
biomedich-1001	160	3	other	other	ADJ
biomedich-1001	160	4	hand	hand	NOUN
biomedich-1001	160	5	,	,	PUNCT
biomedich-1001	160	6	a	a	DET
biomedich-1001	160	7	log	log	NOUN
biomedich-1001	160	8	p	p	NOUN
biomedich-1001	160	9	value	value	NOUN
biomedich-1001	160	10	that	that	PRON
biomedich-1001	160	11	is	be	AUX
biomedich-1001	160	12	too	too	ADV
biomedich-1001	160	13	low	low	ADJ
biomedich-1001	160	14	means	mean	VERB
biomedich-1001	160	15	the	the	DET
biomedich-1001	160	16	compound	compound	NOUN
biomedich-1001	160	17	is	be	AUX
biomedich-1001	160	18	more	more	ADV
biomedich-1001	160	19	hydrophilic	hydrophilic	ADJ
biomedich-1001	160	20	and	and	CCONJ
biomedich-1001	160	21	may	may	AUX
biomedich-1001	160	22	not	not	PART
biomedich-1001	160	23	be	be	AUX
biomedich-1001	160	24	able	able	ADJ
biomedich-1001	160	25	to	to	PART
biomedich-1001	160	26	pass	pass	VERB
biomedich-1001	160	27	through	through	ADP
biomedich-1001	160	28	the	the	DET
biomedich-1001	160	29	lipid	lipid	NOUN
biomedich-1001	160	30	bilayer	bilayer	NOUN
biomedich-1001	160	31	effectively	effectively	ADV
biomedich-1001	160	32	(	(	PUNCT
biomedich-1001	160	33	kelutur	kelutur	PROPN
biomedich-1001	160	34	et	et	PROPN
biomedich-1001	160	35	al	al	PROPN
biomedich-1001	160	36	.	.	PROPN
biomedich-1001	160	37	,	,	PUNCT
biomedich-1001	160	38	2020	2020	NUM
biomedich-1001	160	39	)	)	PUNCT
biomedich-1001	160	40	.	.	PUNCT
biomedich-1001	161	1	the	the	DET
biomedich-1001	161	2	number	number	NOUN
biomedich-1001	161	3	of	of	ADP
biomedich-1001	161	4	hydrogen	hydrogen	NOUN
biomedich-1001	161	5	bond	bond	NOUN
biomedich-1001	161	6	donors	donor	NOUN
biomedich-1001	161	7	and	and	CCONJ
biomedich-1001	161	8	acceptors	acceptor	NOUN
biomedich-1001	161	9	is	be	AUX
biomedich-1001	161	10	related	relate	VERB
biomedich-1001	161	11	to	to	ADP
biomedich-1001	161	12	the	the	DET
biomedich-1001	161	13	biological	biological	ADJ
biomedich-1001	161	14	activity	activity	NOUN
biomedich-1001	161	15	of	of	ADP
biomedich-1001	161	16	a	a	DET
biomedich-1001	161	17	drug	drug	NOUN
biomedich-1001	161	18	.	.	PUNCT
biomedich-1001	162	1	the	the	PRON
biomedich-1001	162	2	greater	great	ADJ
biomedich-1001	162	3	the	the	DET
biomedich-1001	162	4	number	number	NOUN
biomedich-1001	162	5	of	of	ADP
biomedich-1001	162	6	hydrogen	hydrogen	NOUN
biomedich-1001	162	7	bonds	bond	NOUN
biomedich-1001	162	8	,	,	PUNCT
biomedich-1001	162	9	the	the	PRON
biomedich-1001	162	10	higher	high	ADJ
biomedich-1001	162	11	the	the	DET
biomedich-1001	162	12	energy	energy	NOUN
biomedich-1001	162	13	required	require	VERB
biomedich-1001	162	14	for	for	SCONJ
biomedich-1001	162	15	the	the	DET
biomedich-1001	162	16	absorption	absorption	NOUN
biomedich-1001	162	17	process	process	NOUN
biomedich-1001	162	18	to	to	PART
biomedich-1001	162	19	occur	occur	VERB
biomedich-1001	162	20	.	.	PUNCT
biomedich-1001	163	1	the	the	DET
biomedich-1001	163	2	molar	molar	ADJ
biomedich-1001	163	3	refractivity	refractivity	NOUN
biomedich-1001	163	4	parameter	parameter	NOUN
biomedich-1001	163	5	is	be	AUX
biomedich-1001	163	6	the	the	DET
biomedich-1001	163	7	total	total	ADJ
biomedich-1001	163	8	polarizability	polarizability	NOUN
biomedich-1001	163	9	value	value	NOUN
biomedich-1001	163	10	of	of	ADP
biomedich-1001	163	11	a	a	DET
biomedich-1001	163	12	drug	drug	NOUN
biomedich-1001	163	13	compound	compound	NOUN
biomedich-1001	163	14	,	,	PUNCT
biomedich-1001	163	15	where	where	SCONJ
biomedich-1001	163	16	non	non	ADJ
biomedich-1001	163	17	-	-	ADJ
biomedich-1001	163	18	polar	polar	ADJ
biomedich-1001	163	19	compounds	compound	NOUN
biomedich-1001	163	20	will	will	AUX
biomedich-1001	163	21	form	form	VERB
biomedich-1001	163	22	momentum	momentum	NOUN
biomedich-1001	163	23	that	that	PRON
biomedich-1001	163	24	causes	cause	VERB
biomedich-1001	163	25	them	they	PRON
biomedich-1001	163	26	to	to	PART
biomedich-1001	163	27	bind	bind	VERB
biomedich-1001	163	28	with	with	ADP
biomedich-1001	163	29	receptors	receptor	NOUN
biomedich-1001	163	30	,	,	PUNCT
biomedich-1001	163	31	whereas	whereas	SCONJ
biomedich-1001	163	32	polar	polar	ADJ
biomedich-1001	163	33	ones	one	NOUN
biomedich-1001	163	34	play	play	VERB
biomedich-1001	163	35	a	a	DET
biomedich-1001	163	36	role	role	NOUN
biomedich-1001	163	37	in	in	ADP
biomedich-1001	163	38	the	the	DET
biomedich-1001	163	39	elimination	elimination	NOUN
biomedich-1001	163	40	of	of	ADP
biomedich-1001	163	41	metabolic	metabolic	NOUN
biomedich-1001	163	42	residues	residue	NOUN
biomedich-1001	163	43	from	from	ADP
biomedich-1001	163	44	the	the	DET
biomedich-1001	163	45	body	body	NOUN
biomedich-1001	163	46	(	(	PUNCT
biomedich-1001	163	47	frimayanti	frimayanti	NOUN
biomedich-1001	163	48	et	et	PROPN
biomedich-1001	163	49	al	al	PROPN
biomedich-1001	163	50	.	.	PROPN
biomedich-1001	163	51	,	,	PUNCT
biomedich-1001	163	52	2021	2021	NUM
biomedich-1001	163	53	)	)	PUNCT
biomedich-1001	163	54	.	.	PUNCT
biomedich-1001	164	1	according	accord	VERB
biomedich-1001	164	2	to	to	ADP
biomedich-1001	164	3	table	table	NOUN
biomedich-1001	164	4	3	3	NUM
biomedich-1001	164	5	,	,	PUNCT
biomedich-1001	164	6	it	it	PRON
biomedich-1001	164	7	can	can	AUX
biomedich-1001	164	8	be	be	AUX
biomedich-1001	164	9	seen	see	VERB
biomedich-1001	164	10	that	that	SCONJ
biomedich-1001	164	11	all	all	DET
biomedich-1001	164	12	tested	test	VERB
biomedich-1001	164	13	compounds	compound	NOUN
biomedich-1001	164	14	meet	meet	VERB
biomedich-1001	164	15	all	all	PRON
biomedich-1001	164	16	of	of	ADP
biomedich-1001	164	17	lipinski	lipinski	PROPN
biomedich-1001	164	18	’s	’s	PART
biomedich-1001	164	19	parameters	parameter	NOUN
biomedich-1001	164	20	,	,	PUNCT
biomedich-1001	164	21	so	so	ADV
biomedich-1001	164	22	all	all	DET
biomedich-1001	164	23	tested	test	VERB
biomedich-1001	164	24	compounds	compound	NOUN
biomedich-1001	164	25	can	can	AUX
biomedich-1001	164	26	be	be	AUX
biomedich-1001	164	27	considered	consider	VERB
biomedich-1001	164	28	as	as	ADP
biomedich-1001	164	29	candidates	candidate	NOUN
biomedich-1001	164	30	for	for	ADP
biomedich-1001	164	31	oral	oral	ADJ
biomedich-1001	164	32	drugs	drug	NOUN
biomedich-1001	164	33	.	.	PUNCT
biomedich-1001	165	1	the	the	DET
biomedich-1001	165	2	oral	oral	ADJ
biomedich-1001	165	3	dosage	dosage	NOUN
biomedich-1001	165	4	forms	form	NOUN
biomedich-1001	165	5	include	include	VERB
biomedich-1001	165	6	tablets	tablet	NOUN
biomedich-1001	165	7	,	,	PUNCT
biomedich-1001	165	8	capsules	capsule	NOUN
biomedich-1001	165	9	,	,	PUNCT
biomedich-1001	165	10	syrups	syrup	NOUN
biomedich-1001	165	11	,	,	PUNCT
biomedich-1001	165	12	and	and	CCONJ
biomedich-1001	165	13	lozenges	lozenge	NOUN
biomedich-1001	165	14	(	(	PUNCT
biomedich-1001	165	15	nurhikma	nurhikma	NOUN
biomedich-1001	165	16	et	et	NOUN
biomedich-1001	165	17	al	al	PROPN
biomedich-1001	165	18	.	.	PROPN
biomedich-1001	165	19	,	,	PUNCT
biomedich-1001	165	20	2024	2024	NUM
biomedich-1001	165	21	)	)	PUNCT
biomedich-1001	165	22	.	.	PUNCT
biomedich-1001	166	1	molecular	molecular	ADJ
biomedich-1001	166	2	docking	docking	NOUN
biomedich-1001	166	3	is	be	AUX
biomedich-1001	166	4	the	the	DET
biomedich-1001	166	5	process	process	NOUN
biomedich-1001	166	6	of	of	ADP
biomedich-1001	166	7	anchoring	anchor	VERB
biomedich-1001	166	8	a	a	DET
biomedich-1001	166	9	molecule	molecule	NOUN
biomedich-1001	166	10	to	to	ADP
biomedich-1001	166	11	a	a	DET
biomedich-1001	166	12	receptor	receptor	NOUN
biomedich-1001	166	13	through	through	ADP
biomedich-1001	166	14	computer	computer	NOUN
biomedich-1001	166	15	representation	representation	NOUN
biomedich-1001	166	16	.	.	PUNCT
biomedich-1001	167	1	the	the	DET
biomedich-1001	167	2	parameters	parameter	NOUN
biomedich-1001	167	3	analyzed	analyze	VERB
biomedich-1001	167	4	from	from	ADP
biomedich-1001	167	5	this	this	DET
biomedich-1001	167	6	process	process	NOUN
biomedich-1001	167	7	are	be	AUX
biomedich-1001	167	8	the	the	DET
biomedich-1001	167	9	binding	bind	VERB
biomedich-1001	167	10	energy	energy	NOUN
biomedich-1001	167	11	(	(	PUNCT
biomedich-1001	167	12	δg	δg	NOUN
biomedich-1001	167	13	)	)	PUNCT
biomedich-1001	167	14	and	and	CCONJ
biomedich-1001	167	15	inhibition	inhibition	VERB
biomedich-1001	167	16	constant	constant	ADJ
biomedich-1001	167	17	(	(	PUNCT
biomedich-1001	167	18	ki	ki	PROPN
biomedich-1001	167	19	)	)	PUNCT
biomedich-1001	167	20	(	(	PUNCT
biomedich-1001	167	21	ikhlas	ikhlas	PROPN
biomedich-1001	167	22	et	et	PROPN
biomedich-1001	167	23	al	al	PROPN
biomedich-1001	167	24	.	.	PROPN
biomedich-1001	167	25	,	,	PUNCT
biomedich-1001	167	26	2023	2023	NUM
biomedich-1001	167	27	)	)	PUNCT
biomedich-1001	167	28	.	.	PUNCT
biomedich-1001	168	1	binding	bind	VERB
biomedich-1001	168	2	energy	energy	NOUN
biomedich-1001	168	3	and	and	CCONJ
biomedich-1001	168	4	the	the	DET
biomedich-1001	168	5	inhibition	inhibition	NOUN
biomedich-1001	168	6	constant	constant	ADJ
biomedich-1001	168	7	are	be	AUX
biomedich-1001	168	8	related	relate	VERB
biomedich-1001	168	9	to	to	ADP
biomedich-1001	168	10	binding	bind	VERB
biomedich-1001	168	11	affinity	affinity	NOUN
biomedich-1001	168	12	.	.	PUNCT
biomedich-1001	169	1	the	the	PRON
biomedich-1001	169	2	lower	low	ADJ
biomedich-1001	169	3	the	the	DET
biomedich-1001	169	4	binding	bind	VERB
biomedich-1001	169	5	affinity	affinity	NOUN
biomedich-1001	169	6	,	,	PUNCT
biomedich-1001	169	7	the	the	DET
biomedich-1001	169	8	less	less	ADJ
biomedich-1001	169	9	energy	energy	NOUN
biomedich-1001	169	10	is	be	AUX
biomedich-1001	169	11	required	require	VERB
biomedich-1001	169	12	for	for	SCONJ
biomedich-1001	169	13	the	the	DET
biomedich-1001	169	14	compound	compound	NOUN
biomedich-1001	169	15	to	to	PART
biomedich-1001	169	16	bind	bind	VERB
biomedich-1001	169	17	or	or	CCONJ
biomedich-1001	169	18	interact	interact	VERB
biomedich-1001	169	19	with	with	ADP
biomedich-1001	169	20	the	the	DET
biomedich-1001	169	21	target	target	NOUN
biomedich-1001	169	22	receptor	receptor	NOUN
biomedich-1001	169	23	.	.	PUNCT
biomedich-1001	170	1	a	a	DET
biomedich-1001	170	2	low	low	ADJ
biomedich-1001	170	3	free	free	ADJ
biomedich-1001	170	4	binding	bind	VERB
biomedich-1001	170	5	energy	energy	NOUN
biomedich-1001	170	6	value	value	NOUN
biomedich-1001	170	7	indicates	indicate	VERB
biomedich-1001	170	8	that	that	SCONJ
biomedich-1001	170	9	the	the	DET
biomedich-1001	170	10	formed	form	VERB
biomedich-1001	170	11	ligandprotein	ligandprotein	ADJ
biomedich-1001	170	12	binding	bind	VERB
biomedich-1001	170	13	complex	complex	NOUN
biomedich-1001	170	14	will	will	AUX
biomedich-1001	170	15	be	be	AUX
biomedich-1001	170	16	more	more	ADV
biomedich-1001	170	17	stable	stable	ADJ
biomedich-1001	170	18	.	.	PUNCT
biomedich-1001	171	1	if	if	SCONJ
biomedich-1001	171	2	the	the	DET
biomedich-1001	171	3	ligand	ligand	NOUN
biomedich-1001	171	4	's	's	PART
biomedich-1001	171	5	binding	binding	NOUN
biomedich-1001	171	6	to	to	ADP
biomedich-1001	171	7	the	the	DET
biomedich-1001	171	8	receptor	receptor	NOUN
biomedich-1001	171	9	is	be	AUX
biomedich-1001	171	10	more	more	ADV
biomedich-1001	171	11	stable	stable	ADJ
biomedich-1001	171	12	,	,	PUNCT
biomedich-1001	171	13	it	it	PRON
biomedich-1001	171	14	can	can	AUX
biomedich-1001	171	15	be	be	AUX
biomedich-1001	171	16	predicted	predict	VERB
biomedich-1001	171	17	that	that	SCONJ
biomedich-1001	171	18	its	its	PRON
biomedich-1001	171	19	activity	activity	NOUN
biomedich-1001	171	20	will	will	AUX
biomedich-1001	171	21	also	also	ADV
biomedich-1001	171	22	be	be	AUX
biomedich-1001	171	23	greater	great	ADJ
biomedich-1001	171	24	(	(	PUNCT
biomedich-1001	171	25	faqiha	faqiha	NOUN
biomedich-1001	171	26	et	et	PROPN
biomedich-1001	171	27	al	al	PROPN
biomedich-1001	171	28	.	.	PROPN
biomedich-1001	171	29	,	,	PUNCT
biomedich-1001	171	30	2022	2022	NUM
biomedich-1001	171	31	)	)	PUNCT
biomedich-1001	171	32	.	.	PUNCT
biomedich-1001	172	1	the	the	DET
biomedich-1001	172	2	free	free	ADJ
biomedich-1001	172	3	binding	bind	VERB
biomedich-1001	172	4	energy	energy	NOUN
biomedich-1001	172	5	value	value	NOUN
biomedich-1001	172	6	is	be	AUX
biomedich-1001	172	7	related	relate	VERB
biomedich-1001	172	8	to	to	ADP
biomedich-1001	172	9	the	the	DET
biomedich-1001	172	10	ki	ki	PROPN
biomedich-1001	172	11	value	value	NOUN
biomedich-1001	172	12	;	;	PUNCT
biomedich-1001	172	13	the	the	PRON
biomedich-1001	172	14	lower	low	ADJ
biomedich-1001	172	15	the	the	DET
biomedich-1001	172	16	free	free	ADJ
biomedich-1001	172	17	binding	bind	VERB
biomedich-1001	172	18	energy	energy	NOUN
biomedich-1001	172	19	,	,	PUNCT
biomedich-1001	172	20	the	the	PRON
biomedich-1001	172	21	lower	low	ADJ
biomedich-1001	172	22	the	the	DET
biomedich-1001	172	23	ki	ki	PROPN
biomedich-1001	172	24	value	value	NOUN
biomedich-1001	172	25	(	(	PUNCT
biomedich-1001	172	26	fakih	fakih	VERB
biomedich-1001	172	27	et	et	PROPN
biomedich-1001	172	28	al	al	PROPN
biomedich-1001	172	29	.	.	PROPN
biomedich-1001	172	30	,	,	PUNCT
biomedich-1001	172	31	2021	2021	NUM
biomedich-1001	172	32	)	)	PUNCT
biomedich-1001	172	33	.	.	PUNCT
biomedich-1001	173	1	a	a	DET
biomedich-1001	173	2	lower	low	ADJ
biomedich-1001	173	3	ki	ki	PROPN
biomedich-1001	173	4	value	value	NOUN
biomedich-1001	173	5	means	mean	VERB
biomedich-1001	173	6	a	a	DET
biomedich-1001	173	7	smaller	small	ADJ
biomedich-1001	173	8	concentration	concentration	NOUN
biomedich-1001	173	9	of	of	ADP
biomedich-1001	173	10	molecules	molecule	NOUN
biomedich-1001	173	11	is	be	AUX
biomedich-1001	173	12	required	require	VERB
biomedich-1001	173	13	to	to	PART
biomedich-1001	173	14	inhibit	inhibit	VERB
biomedich-1001	173	15	the	the	DET
biomedich-1001	173	16	target	target	NOUN
biomedich-1001	173	17	receptor	receptor	NOUN
biomedich-1001	173	18	(	(	PUNCT
biomedich-1001	173	19	kartika	kartika	PROPN
biomedich-1001	173	20	&	&	CCONJ
biomedich-1001	173	21	ruswanto	ruswanto	NOUN
biomedich-1001	173	22	,	,	PUNCT
biomedich-1001	173	23	2021	2021	NUM
biomedich-1001	173	24	)	)	PUNCT
biomedich-1001	173	25	.	.	PUNCT
biomedich-1001	174	1	this	this	DET
biomedich-1001	174	2	visualization	visualization	NOUN
biomedich-1001	174	3	is	be	AUX
biomedich-1001	174	4	performed	perform	VERB
biomedich-1001	174	5	to	to	PART
biomedich-1001	174	6	understand	understand	VERB
biomedich-1001	174	7	the	the	DET
biomedich-1001	174	8	interactions	interaction	NOUN
biomedich-1001	174	9	that	that	PRON
biomedich-1001	174	10	occur	occur	VERB
biomedich-1001	174	11	between	between	ADP
biomedich-1001	174	12	ligands	ligand	NOUN
biomedich-1001	174	13	and	and	CCONJ
biomedich-1001	174	14	receptors	receptor	NOUN
biomedich-1001	174	15	.	.	PUNCT
biomedich-1001	175	1	the	the	DET
biomedich-1001	175	2	interactions	interaction	NOUN
biomedich-1001	175	3	analyzed	analyze	VERB
biomedich-1001	175	4	are	be	AUX
biomedich-1001	175	5	hydrogen	hydrogen	NOUN
biomedich-1001	175	6	bonds	bond	NOUN
biomedich-1001	175	7	and	and	CCONJ
biomedich-1001	175	8	hydrophobic	hydrophobic	NOUN
biomedich-1001	175	9	interactions	interaction	NOUN
biomedich-1001	175	10	,	,	PUNCT
biomedich-1001	175	11	as	as	SCONJ
biomedich-1001	175	12	both	both	DET
biomedich-1001	175	13	types	type	NOUN
biomedich-1001	175	14	of	of	ADP
biomedich-1001	175	15	bonds	bond	NOUN
biomedich-1001	175	16	can	can	AUX
biomedich-1001	175	17	influence	influence	VERB
biomedich-1001	175	18	the	the	DET
biomedich-1001	175	19	physicochemical	physicochemical	ADJ
biomedich-1001	175	20	properties	property	NOUN
biomedich-1001	175	21	of	of	ADP
biomedich-1001	175	22	drugs	drug	NOUN
biomedich-1001	175	23	and	and	CCONJ
biomedich-1001	175	24	the	the	DET
biomedich-1001	175	25	stability	stability	NOUN
biomedich-1001	175	26	of	of	ADP
biomedich-1001	175	27	the	the	DET
biomedich-1001	175	28	conformation	conformation	NOUN
biomedich-1001	175	29	that	that	PRON
biomedich-1001	175	30	occurs	occur	VERB
biomedich-1001	175	31	.	.	PUNCT
biomedich-1001	176	1	hydrogen	hydrogen	NOUN
biomedich-1001	176	2	bonds	bond	NOUN
biomedich-1001	176	3	are	be	AUX
biomedich-1001	176	4	bonds	bond	NOUN
biomedich-1001	176	5	that	that	PRON
biomedich-1001	176	6	occur	occur	VERB
biomedich-1001	176	7	between	between	ADP
biomedich-1001	176	8	hydrogen	hydrogen	NOUN
biomedich-1001	176	9	atoms	atom	NOUN
biomedich-1001	176	10	and	and	CCONJ
biomedich-1001	176	11	n	n	CCONJ
biomedich-1001	176	12	,	,	PUNCT
biomedich-1001	176	13	o	o	NOUN
biomedich-1001	176	14	,	,	PUNCT
biomedich-1001	176	15	or	or	CCONJ
biomedich-1001	176	16	f	f	PROPN
biomedich-1001	176	17	atoms	atom	NOUN
biomedich-1001	176	18	(	(	PUNCT
biomedich-1001	176	19	vinsiah	vinsiah	PROPN
biomedich-1001	176	20	&	&	CCONJ
biomedich-1001	176	21	fadhillah	fadhillah	PROPN
biomedich-1001	176	22	,	,	PUNCT
biomedich-1001	176	23	2018	2018	NUM
biomedich-1001	176	24	)	)	PUNCT
biomedich-1001	176	25	.	.	PUNCT
biomedich-1001	177	1	therefore	therefore	ADV
biomedich-1001	177	2	,	,	PUNCT
biomedich-1001	177	3	hydrogen	hydrogen	NOUN
biomedich-1001	177	4	bonds	bond	NOUN
biomedich-1001	177	5	contribute	contribute	VERB
biomedich-1001	177	6	to	to	ADP
biomedich-1001	177	7	the	the	DET
biomedich-1001	177	8	affinity	affinity	NOUN
biomedich-1001	177	9	of	of	ADP
biomedich-1001	177	10	a	a	DET
biomedich-1001	177	11	molecule	molecule	NOUN
biomedich-1001	177	12	for	for	ADP
biomedich-1001	177	13	a	a	DET
biomedich-1001	177	14	target	target	NOUN
biomedich-1001	177	15	protein	protein	NOUN
biomedich-1001	177	16	.	.	PUNCT
biomedich-1001	178	1	if	if	SCONJ
biomedich-1001	178	2	there	there	PRON
biomedich-1001	178	3	are	be	VERB
biomedich-1001	178	4	many	many	ADJ
biomedich-1001	178	5	hydrogen	hydrogen	NOUN
biomedich-1001	178	6	bonds	bond	NOUN
biomedich-1001	178	7	accompanied	accompany	VERB
biomedich-1001	178	8	by	by	ADP
biomedich-1001	178	9	hydrophobic	hydrophobic	NOUN
biomedich-1001	178	10	bonds	bond	NOUN
biomedich-1001	178	11	,	,	PUNCT
biomedich-1001	178	12	it	it	PRON
biomedich-1001	178	13	can	can	AUX
biomedich-1001	178	14	be	be	AUX
biomedich-1001	178	15	said	say	VERB
biomedich-1001	178	16	that	that	SCONJ
biomedich-1001	178	17	the	the	DET
biomedich-1001	178	18	interaction	interaction	NOUN
biomedich-1001	178	19	between	between	ADP
biomedich-1001	178	20	the	the	DET
biomedich-1001	178	21	ligand	ligand	NOUN
biomedich-1001	178	22	and	and	CCONJ
biomedich-1001	178	23	receptor	receptor	NOUN
biomedich-1001	178	24	is	be	AUX
biomedich-1001	178	25	a	a	DET
biomedich-1001	178	26	strong	strong	ADJ
biomedich-1001	178	27	interaction	interaction	NOUN
biomedich-1001	178	28	.	.	PUNCT
biomedich-1001	179	1	hydrophobic	hydrophobic	NOUN
biomedich-1001	179	2	bonds	bond	NOUN
biomedich-1001	179	3	are	be	AUX
biomedich-1001	179	4	interactions	interaction	NOUN
biomedich-1001	179	5	between	between	ADP
biomedich-1001	179	6	amino	amino	ADJ
biomedich-1001	179	7	acids	acid	NOUN
biomedich-1001	179	8	on	on	ADP
biomedich-1001	179	9	the	the	DET
biomedich-1001	179	10	ligand	ligand	NOUN
biomedich-1001	179	11	and	and	CCONJ
biomedich-1001	179	12	receptor	receptor	NOUN
biomedich-1001	179	13	that	that	PRON
biomedich-1001	179	14	help	help	VERB
biomedich-1001	179	15	maintain	maintain	VERB
biomedich-1001	179	16	the	the	DET
biomedich-1001	179	17	binding	bind	VERB
biomedich-1001	179	18	conformation	conformation	NOUN
biomedich-1001	179	19	(	(	PUNCT
biomedich-1001	179	20	zubair	zubair	PROPN
biomedich-1001	179	21	et	et	PROPN
biomedich-1001	179	22	al	al	PROPN
biomedich-1001	179	23	.	.	PROPN
biomedich-1001	179	24	,	,	PUNCT
biomedich-1001	179	25	2020	2020	NUM
biomedich-1001	179	26	)	)	PUNCT
biomedich-1001	179	27	.	.	PUNCT
biomedich-1001	180	1	hydrophobic	hydrophobic	NOUN
biomedich-1001	180	2	bonds	bond	NOUN
biomedich-1001	180	3	combine	combine	VERB
biomedich-1001	180	4	polar	polar	ADJ
biomedich-1001	180	5	areas	area	NOUN
biomedich-1001	180	6	of	of	ADP
biomedich-1001	180	7	the	the	DET
biomedich-1001	180	8	drug	drug	NOUN
biomedich-1001	180	9	molecule	molecule	NOUN
biomedich-1001	180	10	with	with	ADP
biomedich-1001	180	11	polar	polar	ADJ
biomedich-1001	180	12	areas	area	NOUN
biomedich-1001	180	13	of	of	ADP
biomedich-1001	180	14	the	the	DET
biomedich-1001	180	15	biological	biological	ADJ
biomedich-1001	180	16	receptor	receptor	NOUN
biomedich-1001	180	17	.	.	PUNCT
biomedich-1001	181	1	hydrophobic	hydrophobic	NOUN
biomedich-1001	181	2	interactions	interaction	NOUN
biomedich-1001	181	3	can	can	AUX
biomedich-1001	181	4	affect	affect	VERB
biomedich-1001	181	5	the	the	DET
biomedich-1001	181	6	stability	stability	NOUN
biomedich-1001	181	7	of	of	ADP
biomedich-1001	181	8	the	the	DET
biomedich-1001	181	9	bond	bond	NOUN
biomedich-1001	181	10	between	between	ADP
biomedich-1001	181	11	the	the	DET
biomedich-1001	181	12	compound	compound	NOUN
biomedich-1001	181	13	and	and	CCONJ
biomedich-1001	181	14	the	the	DET
biomedich-1001	181	15	receptor	receptor	NOUN
biomedich-1001	181	16	.	.	PUNCT
biomedich-1001	182	1	in	in	ADP
biomedich-1001	182	2	allopurinol	allopurinol	NOUN
biomedich-1001	182	3	,	,	PUNCT
biomedich-1001	182	4	the	the	DET
biomedich-1001	182	5	amino	amino	NOUN
biomedich-1001	182	6	acid	acid	NOUN
biomedich-1001	182	7	residues	residue	NOUN
biomedich-1001	182	8	that	that	PRON
biomedich-1001	182	9	play	play	VERB
biomedich-1001	182	10	a	a	DET
biomedich-1001	182	11	role	role	NOUN
biomedich-1001	182	12	in	in	ADP
biomedich-1001	182	13	hydrophobic	hydrophobic	NOUN
biomedich-1001	182	14	bonding	bonding	NOUN
biomedich-1001	182	15	are	be	AUX
biomedich-1001	182	16	phe914	phe914	PROPN
biomedich-1001	182	17	and	and	CCONJ
biomedich-1001	182	18	ala1078	ala1078	ADJ
biomedich-1001	182	19	.	.	PUNCT
biomedich-1001	183	1	in	in	ADP
biomedich-1001	183	2	the	the	DET
biomedich-1001	183	3	compound	compound	NOUN
biomedich-1001	183	4	5	5	NUM
biomedich-1001	183	5	-	-	SYM
biomedich-1001	183	6	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	183	7	,	,	PUNCT
biomedich-1001	183	8	the	the	DET
biomedich-1001	183	9	amino	amino	NOUN
biomedich-1001	183	10	acid	acid	NOUN
biomedich-1001	183	11	residues	residue	NOUN
biomedich-1001	183	12	that	that	PRON
biomedich-1001	183	13	contribute	contribute	VERB
biomedich-1001	183	14	to	to	ADP
biomedich-1001	183	15	hydrophobic	hydrophobic	NOUN
biomedich-1001	183	16	bonding	bonding	NOUN
biomedich-1001	183	17	are	be	AUX
biomedich-1001	183	18	ala1078	ala1078	ADJ
biomedich-1001	183	19	,	,	PUNCT
biomedich-1001	183	20	ala1079	ala1079	PROPN
biomedich-1001	183	21	,	,	PUNCT
biomedich-1001	183	22	phe914	phe914	PROPN
biomedich-1001	183	23	,	,	PUNCT
biomedich-1001	183	24	ala910	ala910	PROPN
biomedich-1001	183	25	,	,	PUNCT
biomedich-1001	183	26	leu1014	leu1014	NOUN
biomedich-1001	183	27	,	,	PUNCT
biomedich-1001	183	28	leu873	leu873	PROPN
biomedich-1001	183	29	,	,	PUNCT
biomedich-1001	183	30	val1011	val1011	NOUN
biomedich-1001	183	31	,	,	PUNCT
biomedich-1001	183	32	and	and	CCONJ
biomedich-1001	183	33	it	it	PRON
biomedich-1001	183	34	has	have	VERB
biomedich-1001	183	35	3	3	NUM
biomedich-1001	183	36	amino	amino	NOUN
biomedich-1001	183	37	acid	acid	NOUN
biomedich-1001	183	38	residues	residue	NOUN
biomedich-1001	183	39	that	that	PRON
biomedich-1001	183	40	are	be	AUX
biomedich-1001	183	41	the	the	DET
biomedich-1001	183	42	same	same	ADJ
biomedich-1001	183	43	as	as	ADP
biomedich-1001	183	44	allopurinol	allopurinol	NOUN
biomedich-1001	183	45	,	,	PUNCT
biomedich-1001	183	46	namely	namely	ADV
biomedich-1001	183	47	ala1078	ala1078	ADJ
biomedich-1001	183	48	,	,	PUNCT
biomedich-1001	183	49	phe914	phe914	PROPN
biomedich-1001	183	50	,	,	PUNCT
biomedich-1001	183	51	and	and	CCONJ
biomedich-1001	183	52	val1011	val1011	NOUN
biomedich-1001	183	53	.	.	PUNCT
biomedich-1001	184	1	in	in	ADP
biomedich-1001	184	2	the	the	DET
biomedich-1001	184	3	kaempferol	kaempferol	NOUN
biomedich-1001	184	4	compound	compound	NOUN
biomedich-1001	184	5	,	,	PUNCT
biomedich-1001	184	6	the	the	DET
biomedich-1001	184	7	amino	amino	NOUN
biomedich-1001	184	8	acid	acid	NOUN
biomedich-1001	184	9	residues	residue	NOUN
biomedich-1001	184	10	involved	involve	VERB
biomedich-1001	184	11	in	in	ADP
biomedich-1001	184	12	hydrophobic	hydrophobic	NOUN
biomedich-1001	184	13	bonding	bonding	NOUN
biomedich-1001	184	14	are	be	AUX
biomedich-1001	184	15	ala1078	ala1078	ADJ
biomedich-1001	184	16	,	,	PUNCT
biomedich-1001	184	17	ala1079	ala1079	PROPN
biomedich-1001	184	18	,	,	PUNCT
biomedich-1001	184	19	phe914	phe914	PROPN
biomedich-1001	184	20	,	,	PUNCT
biomedich-1001	184	21	ala910	ala910	PROPN
biomedich-1001	184	22	,	,	PUNCT
biomedich-1001	184	23	leu1014	leu1014	NOUN
biomedich-1001	184	24	,	,	PUNCT
biomedich-1001	184	25	leu873	leu873	PROPN
biomedich-1001	184	26	,	,	PUNCT
biomedich-1001	184	27	and	and	CCONJ
biomedich-1001	184	28	it	it	PRON
biomedich-1001	184	29	has	have	VERB
biomedich-1001	184	30	2	2	NUM
biomedich-1001	184	31	amino	amino	NOUN
biomedich-1001	184	32	acid	acid	NOUN
biomedich-1001	184	33	residues	residue	NOUN
biomedich-1001	184	34	that	that	PRON
biomedich-1001	184	35	are	be	AUX
biomedich-1001	184	36	the	the	DET
biomedich-1001	184	37	same	same	ADJ
biomedich-1001	184	38	as	as	ADP
biomedich-1001	184	39	allopurinol	allopurinol	NOUN
biomedich-1001	184	40	,	,	PUNCT
biomedich-1001	184	41	which	which	PRON
biomedich-1001	184	42	are	be	AUX
biomedich-1001	184	43	phe914	phe914	PROPN
biomedich-1001	184	44	and	and	CCONJ
biomedich-1001	184	45	ala1078	ala1078	ADJ
biomedich-1001	184	46	.	.	PUNCT
biomedich-1001	185	1	the	the	DET
biomedich-1001	185	2	similarity	similarity	NOUN
biomedich-1001	185	3	in	in	ADP
biomedich-1001	185	4	the	the	DET
biomedich-1001	185	5	amino	amino	NOUN
biomedich-1001	185	6	acid	acid	NOUN
biomedich-1001	185	7	residues	residue	NOUN
biomedich-1001	185	8	of	of	ADP
biomedich-1001	185	9	hydrogen	hydrogen	NOUN
biomedich-1001	185	10	bonds	bond	NOUN
biomedich-1001	185	11	and	and	CCONJ
biomedich-1001	185	12	hydrophobic	hydrophobic	NOUN
biomedich-1001	185	13	bonds	bond	NOUN
biomedich-1001	185	14	between	between	ADP
biomedich-1001	185	15	the	the	DET
biomedich-1001	185	16	test	test	NOUN
biomedich-1001	185	17	compound	compound	NOUN
biomedich-1001	185	18	and	and	CCONJ
biomedich-1001	185	19	the	the	DET
biomedich-1001	185	20	comparator	comparator	NOUN
biomedich-1001	185	21	(	(	PUNCT
biomedich-1001	185	22	allopurinol	allopurinol	NOUN
biomedich-1001	185	23	)	)	PUNCT
biomedich-1001	185	24	indicates	indicate	VERB
biomedich-1001	185	25	that	that	SCONJ
biomedich-1001	185	26	the	the	DET
biomedich-1001	185	27	test	test	NOUN
biomedich-1001	185	28	compound	compound	NOUN
biomedich-1001	185	29	has	have	VERB
biomedich-1001	185	30	similar	similar	ADJ
biomedich-1001	185	31	activity	activity	NOUN
biomedich-1001	185	32	to	to	PART
biomedich-1001	185	33	allopurinol	allopurinol	VERB
biomedich-1001	185	34	which	which	PRON
biomedich-1001	185	35	is	be	AUX
biomedich-1001	185	36	capable	capable	ADJ
biomedich-1001	185	37	of	of	ADP
biomedich-1001	185	38	inhibiting	inhibit	VERB
biomedich-1001	185	39	the	the	DET
biomedich-1001	185	40	activity	activity	NOUN
biomedich-1001	185	41	of	of	ADP
biomedich-1001	185	42	the	the	DET
biomedich-1001	185	43	enzyme	enzyme	NOUN
biomedich-1001	185	44	xanthine	xanthine	NOUN
biomedich-1001	185	45	oxidase	oxidase	NOUN
biomedich-1001	185	46	(	(	PUNCT
biomedich-1001	185	47	dari	dari	NOUN
biomedich-1001	185	48	,	,	PUNCT
biomedich-1001	185	49	2022	2022	NUM
biomedich-1001	185	50	)	)	PUNCT
biomedich-1001	185	51	.	.	PUNCT
biomedich-1001	186	1	this	this	DET
biomedich-1001	186	2	rmsd	rmsd	ADJ
biomedich-1001	186	3	analysis	analysis	NOUN
biomedich-1001	186	4	aims	aim	VERB
biomedich-1001	186	5	to	to	PART
biomedich-1001	186	6	compare	compare	VERB
biomedich-1001	186	7	how	how	SCONJ
biomedich-1001	186	8	the	the	DET
biomedich-1001	186	9	position	position	NOUN
biomedich-1001	186	10	of	of	ADP
biomedich-1001	186	11	the	the	DET
biomedich-1001	186	12	ligand	ligand	ADJ
biomedich-1001	186	13	-	-	PUNCT
biomedich-1001	186	14	receptor	receptor	NOUN
biomedich-1001	186	15	complex	complex	ADJ
biomedich-1001	186	16	changes	change	NOUN
biomedich-1001	186	17	over	over	ADP
biomedich-1001	186	18	time	time	NOUN
biomedich-1001	186	19	during	during	ADP
biomedich-1001	186	20	the	the	DET
biomedich-1001	186	21	simulation	simulation	NOUN
biomedich-1001	186	22	process	process	NOUN
biomedich-1001	186	23	.	.	PUNCT
biomedich-1001	187	1	the	the	DET
biomedich-1001	187	2	rmsd	rmsd	NOUN
biomedich-1001	187	3	results	result	NOUN
biomedich-1001	187	4	for	for	ADP
biomedich-1001	187	5	the	the	DET
biomedich-1001	187	6	compounds	compound	NOUN
biomedich-1001	187	7	betagirin	betagirin	NOUN
biomedich-1001	187	8	and	and	CCONJ
biomedich-1001	187	9	3	3	NUM
biomedich-1001	187	10	-	-	PUNCT
biomedich-1001	187	11	cyclohexene-1methanol	cyclohexene-1methanol	NOUN
biomedich-1001	187	12	along	along	ADP
biomedich-1001	187	13	with	with	ADP
biomedich-1001	187	14	allopurinol	allopurinol	NOUN
biomedich-1001	187	15	indicate	indicate	VERB
biomedich-1001	187	16	an	an	DET
biomedich-1001	187	17	increase	increase	NOUN
biomedich-1001	187	18	in	in	ADP
biomedich-1001	187	19	rmsd	rmsd	ADJ
biomedich-1001	187	20	values	value	NOUN
biomedich-1001	187	21	,	,	PUNCT
biomedich-1001	187	22	which	which	PRON
biomedich-1001	187	23	suggests	suggest	VERB
biomedich-1001	187	24	that	that	SCONJ
biomedich-1001	187	25	the	the	DET
biomedich-1001	187	26	protein	protein	NOUN
biomedich-1001	187	27	structure	structure	NOUN
biomedich-1001	187	28	has	have	AUX
biomedich-1001	187	29	started	start	VERB
biomedich-1001	187	30	to	to	PART
biomedich-1001	187	31	open	open	VERB
biomedich-1001	187	32	and	and	CCONJ
biomedich-1001	187	33	the	the	DET
biomedich-1001	187	34	ligand	ligand	NOUN
biomedich-1001	187	35	is	be	AUX
biomedich-1001	187	36	beginning	begin	VERB
biomedich-1001	187	37	to	to	PART
biomedich-1001	187	38	search	search	VERB
biomedich-1001	187	39	for	for	ADP
biomedich-1001	187	40	a	a	DET
biomedich-1001	187	41	suitable	suitable	ADJ
biomedich-1001	187	42	binding	bind	VERB
biomedich-1001	187	43	location	location	NOUN
biomedich-1001	187	44	on	on	ADP
biomedich-1001	187	45	the	the	DET
biomedich-1001	187	46	receptor	receptor	NOUN
biomedich-1001	187	47	(	(	PUNCT
biomedich-1001	187	48	muttaqin	muttaqin	ADJ
biomedich-1001	187	49	,	,	PUNCT
biomedich-1001	187	50	2019	2019	NUM
biomedich-1001	187	51	)	)	PUNCT
biomedich-1001	187	52	.	.	PUNCT
biomedich-1001	188	1	based	base	VERB
biomedich-1001	188	2	on	on	ADP
biomedich-1001	188	3	the	the	DET
biomedich-1001	188	4	rmsd	rmsd	ADJ
biomedich-1001	188	5	analysis	analysis	NOUN
biomedich-1001	188	6	results	result	NOUN
biomedich-1001	188	7	,	,	PUNCT
biomedich-1001	188	8	the	the	DET
biomedich-1001	188	9	compound	compound	NOUN
biomedich-1001	188	10	kaempferol	kaempferol	NOUN
biomedich-1001	188	11	has	have	VERB
biomedich-1001	188	12	more	more	ADV
biomedich-1001	188	13	stable	stable	ADJ
biomedich-1001	188	14	interactions	interaction	NOUN
biomedich-1001	188	15	compared	compare	VERB
biomedich-1001	188	16	to	to	ADP
biomedich-1001	188	17	the	the	DET
biomedich-1001	188	18	compound	compound	NOUN
biomedich-1001	188	19	5	5	NUM
biomedich-1001	188	20	-	-	SYM
biomedich-1001	188	21	hydroxy-3,7,4'trimethoxyflavone	hydroxy-3,7,4'trimethoxyflavone	NOUN
biomedich-1001	188	22	and	and	CCONJ
biomedich-1001	188	23	allopurinol	allopurinol	VERB
biomedich-1001	188	24	because	because	SCONJ
biomedich-1001	188	25	it	it	PRON
biomedich-1001	188	26	has	have	VERB
biomedich-1001	188	27	a	a	DET
biomedich-1001	188	28	lower	low	ADJ
biomedich-1001	188	29	rmsd	rmsd	NOUN
biomedich-1001	188	30	value	value	NOUN
biomedich-1001	188	31	and	and	CCONJ
biomedich-1001	188	32	the	the	DET
biomedich-1001	188	33	stability	stability	NOUN
biomedich-1001	188	34	of	of	ADP
biomedich-1001	188	35	that	that	DET
biomedich-1001	188	36	compound	compound	NOUN
biomedich-1001	188	37	tends	tend	VERB
biomedich-1001	188	38	to	to	PART
biomedich-1001	188	39	be	be	AUX
biomedich-1001	188	40	more	more	ADV
biomedich-1001	188	41	constant	constant	ADJ
biomedich-1001	188	42	.	.	PUNCT
biomedich-1001	189	1	the	the	DET
biomedich-1001	189	2	root	root	NOUN
biomedich-1001	189	3	mean	mean	VERB
biomedich-1001	189	4	square	square	ADJ
biomedich-1001	189	5	fluctuation	fluctuation	NOUN
biomedich-1001	189	6	parameter	parameter	NOUN
biomedich-1001	189	7	or	or	CCONJ
biomedich-1001	189	8	rmsf	rmsf	NOUN
biomedich-1001	189	9	is	be	AUX
biomedich-1001	189	10	analyzed	analyze	VERB
biomedich-1001	189	11	to	to	PART
biomedich-1001	189	12	determine	determine	VERB
biomedich-1001	189	13	the	the	DET
biomedich-1001	189	14	fluctuations	fluctuation	NOUN
biomedich-1001	189	15	of	of	ADP
biomedich-1001	189	16	ligand	ligand	ADJ
biomedich-1001	189	17	interactions	interaction	NOUN
biomedich-1001	189	18	with	with	ADP
biomedich-1001	189	19	amino	amino	ADJ
biomedich-1001	189	20	acids	acid	NOUN
biomedich-1001	189	21	during	during	ADP
biomedich-1001	189	22	the	the	DET
biomedich-1001	189	23	simulation15	simulation15	NOUN
biomedich-1001	189	24	.	.	PUNCT
biomedich-1001	190	1	based	base	VERB
biomedich-1001	190	2	on	on	ADP
biomedich-1001	190	3	the	the	DET
biomedich-1001	190	4	rmsf	rmsf	NOUN
biomedich-1001	190	5	analysis	analysis	NOUN
biomedich-1001	190	6	results	result	NOUN
biomedich-1001	190	7	in	in	ADP
biomedich-1001	190	8	figure	figure	NOUN
biomedich-1001	190	9	7	7	NUM
biomedich-1001	190	10	,	,	PUNCT
biomedich-1001	190	11	it	it	PRON
biomedich-1001	190	12	can	can	AUX
biomedich-1001	190	13	be	be	AUX
biomedich-1001	190	14	seen	see	VERB
biomedich-1001	190	15	that	that	SCONJ
biomedich-1001	190	16	the	the	DET
biomedich-1001	190	17	fluctuations	fluctuation	NOUN
biomedich-1001	190	18	of	of	ADP
biomedich-1001	190	19	the	the	DET
biomedich-1001	190	20	compounds	compound	NOUN
biomedich-1001	190	21	allopurinol	allopurinol	NOUN
biomedich-1001	190	22	,	,	PUNCT
biomedich-1001	190	23	5	5	NUM
biomedich-1001	190	24	-	-	SYM
biomedich-1001	190	25	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	190	26	,	,	PUNCT
biomedich-1001	190	27	and	and	CCONJ
biomedich-1001	190	28	kaempferol	kaempferol	NOUN
biomedich-1001	190	29	show	show	VERB
biomedich-1001	190	30	almost	almost	ADV
biomedich-1001	190	31	identical	identical	ADJ
biomedich-1001	190	32	fluctuation	fluctuation	NOUN
biomedich-1001	190	33	movements	movement	NOUN
biomedich-1001	190	34	.	.	PUNCT
biomedich-1001	191	1	in	in	ADP
biomedich-1001	191	2	the	the	DET
biomedich-1001	191	3	compound	compound	NOUN
biomedich-1001	191	4	5	5	NUM
biomedich-1001	191	5	-	-	SYM
biomedich-1001	191	6	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NUM
biomedich-1001	191	7	,	,	PUNCT
biomedich-1001	191	8	the	the	DET
biomedich-1001	191	9	amino	amino	NOUN
biomedich-1001	191	10	acid	acid	NOUN
biomedich-1001	191	11	residues	residue	NOUN
biomedich-1001	191	12	that	that	PRON
biomedich-1001	191	13	experienced	experience	VERB
biomedich-1001	191	14	the	the	DET
biomedich-1001	191	15	highest	high	ADJ
biomedich-1001	191	16	fluctuations	fluctuation	NOUN
biomedich-1001	191	17	were	be	AUX
biomedich-1001	191	18	thr1319	thr1319	NOUN
biomedich-1001	191	19	,	,	PUNCT
biomedich-1001	191	20	gly1320	gly1320	NOUN
biomedich-1001	191	21	,	,	PUNCT
biomedich-1001	191	22	and	and	CCONJ
biomedich-1001	191	23	lys1326	lys1326	NOUN
biomedich-1001	191	24	,	,	PUNCT
biomedich-1001	191	25	while	while	SCONJ
biomedich-1001	191	26	the	the	DET
biomedich-1001	191	27	lowest	low	ADJ
biomedich-1001	191	28	fluctuations	fluctuation	NOUN
biomedich-1001	191	29	were	be	AUX
biomedich-1001	191	30	observed	observe	VERB
biomedich-1001	191	31	in	in	ADP
biomedich-1001	191	32	the	the	DET
biomedich-1001	191	33	amino	amino	NOUN
biomedich-1001	191	34	acid	acid	NOUN
biomedich-1001	191	35	residues	residue	NOUN
biomedich-1001	191	36	ile1001	ile1001	NOUN
biomedich-1001	191	37	,	,	PUNCT
biomedich-1001	191	38	ala919	ala919	PROPN
biomedich-1001	191	39	,	,	PUNCT
biomedich-1001	191	40	and	and	CCONJ
biomedich-1001	191	41	ala881	ala881	PROPN
biomedich-1001	191	42	.	.	PUNCT
biomedich-1001	192	1	in	in	ADP
biomedich-1001	192	2	the	the	DET
biomedich-1001	192	3	compound	compound	NOUN
biomedich-1001	192	4	kaempferol	kaempferol	NOUN
biomedich-1001	192	5	,	,	PUNCT
biomedich-1001	192	6	the	the	DET
biomedich-1001	192	7	highest	high	ADJ
biomedich-1001	192	8	fluctuations	fluctuation	NOUN
biomedich-1001	192	9	occurred	occur	VERB
biomedich-1001	192	10	in	in	ADP
biomedich-1001	192	11	the	the	DET
biomedich-1001	192	12	amino	amino	NOUN
biomedich-1001	192	13	acid	acid	NOUN
biomedich-1001	192	14	residues	residue	NOUN
biomedich-1001	192	15	glu1143	glu1143	NOUN
biomedich-1001	192	16	,	,	PUNCT
biomedich-1001	192	17	thr1144	thr1144	ADV
biomedich-1001	192	18	,	,	PUNCT
biomedich-1001	192	19	and	and	CCONJ
biomedich-1001	192	20	asn1145	asn1145	NOUN
biomedich-1001	192	21	,	,	PUNCT
biomedich-1001	192	22	while	while	SCONJ
biomedich-1001	192	23	the	the	DET
biomedich-1001	192	24	lowest	low	ADJ
biomedich-1001	192	25	fluctuations	fluctuation	NOUN
biomedich-1001	192	26	were	be	AUX
biomedich-1001	192	27	seen	see	VERB
biomedich-1001	192	28	in	in	ADP
biomedich-1001	192	29	the	the	DET
biomedich-1001	192	30	amino	amino	NOUN
biomedich-1001	192	31	acid	acid	NOUN
biomedich-1001	192	32	residues	residue	NOUN
biomedich-1001	192	33	cys999	cys999	NOUN
biomedich-1001	192	34	,	,	PUNCT
biomedich-1001	192	35	ile1000	ile1000	NOUN
biomedich-1001	192	36	,	,	PUNCT
biomedich-1001	192	37	and	and	CCONJ
biomedich-1001	192	38	ile1001	ile1001	ADJ
biomedich-1001	192	39	.	.	PUNCT
biomedich-1001	193	1	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	193	2	et	et	PROPN
biomedich-1001	193	3	al	al	PROPN
biomedich-1001	193	4	.	.	PUNCT
biomedich-1001	193	5	–	–	PUNCT
biomedich-1001	193	6	molecular	molecular	ADJ
biomedich-1001	193	7	dynamic	dynamic	ADJ
biomedich-1001	193	8	study	study	NOUN
biomedich-1001	193	9	of	of	ADP
biomedich-1001	193	10	java	java	PROPN
biomedich-1001	193	11	cardamom	cardamom	PROPN
biomedich-1001	193	12	(	(	PUNCT
biomedich-1001	193	13	wurfbania	wurfbania	PROPN
biomedich-1001	193	14	compacta	compacta	PROPN
biomedich-1001	193	15	)	)	PUNCT
biomedich-1001	193	16	…	…	PUNCT
biomedich-1001	193	17	1255	1255	NUM
biomedich-1001	193	18	conversely	conversely	ADV
biomedich-1001	193	19	,	,	PUNCT
biomedich-1001	193	20	in	in	ADP
biomedich-1001	193	21	the	the	DET
biomedich-1001	193	22	reference	reference	NOUN
biomedich-1001	193	23	drug	drug	NOUN
biomedich-1001	193	24	allopurinol	allopurinol	NOUN
biomedich-1001	193	25	,	,	PUNCT
biomedich-1001	193	26	the	the	DET
biomedich-1001	193	27	highest	high	ADJ
biomedich-1001	193	28	fluctuations	fluctuation	NOUN
biomedich-1001	193	29	were	be	AUX
biomedich-1001	193	30	observed	observe	VERB
biomedich-1001	193	31	in	in	ADP
biomedich-1001	193	32	the	the	DET
biomedich-1001	193	33	amino	amino	NOUN
biomedich-1001	193	34	acid	acid	NOUN
biomedich-1001	193	35	residues	residue	NOUN
biomedich-1001	193	36	phe1142	phe1142	NOUN
biomedich-1001	193	37	,	,	PUNCT
biomedich-1001	193	38	glu1143	glu1143	NOUN
biomedich-1001	193	39	,	,	PUNCT
biomedich-1001	193	40	and	and	CCONJ
biomedich-1001	193	41	thr1144	thr1144	ADV
biomedich-1001	193	42	,	,	PUNCT
biomedich-1001	193	43	while	while	SCONJ
biomedich-1001	193	44	the	the	DET
biomedich-1001	193	45	lowest	low	ADJ
biomedich-1001	193	46	fluctuations	fluctuation	NOUN
biomedich-1001	193	47	occurred	occur	VERB
biomedich-1001	193	48	in	in	ADP
biomedich-1001	193	49	the	the	DET
biomedich-1001	193	50	amino	amino	NOUN
biomedich-1001	193	51	acid	acid	NOUN
biomedich-1001	193	52	residues	residue	NOUN
biomedich-1001	193	53	ile1000	ile1000	NOUN
biomedich-1001	193	54	,	,	PUNCT
biomedich-1001	193	55	ile1001	ile1001	NOUN
biomedich-1001	193	56	,	,	PUNCT
biomedich-1001	193	57	and	and	CCONJ
biomedich-1001	193	58	arg804	arg804	PROPN
biomedich-1001	193	59	.	.	PUNCT
biomedich-1001	194	1	amino	amino	NOUN
biomedich-1001	194	2	acid	acid	NOUN
biomedich-1001	194	3	residues	residue	NOUN
biomedich-1001	194	4	with	with	ADP
biomedich-1001	194	5	low	low	ADJ
biomedich-1001	194	6	fluctuation	fluctuation	NOUN
biomedich-1001	194	7	will	will	AUX
biomedich-1001	194	8	have	have	VERB
biomedich-1001	194	9	low	low	ADJ
biomedich-1001	194	10	flexibility	flexibility	NOUN
biomedich-1001	194	11	and	and	CCONJ
biomedich-1001	194	12	demonstrate	demonstrate	VERB
biomedich-1001	194	13	more	more	ADV
biomedich-1001	194	14	stable	stable	ADJ
biomedich-1001	194	15	binding	bind	VERB
biomedich-1001	194	16	interactions	interaction	NOUN
biomedich-1001	194	17	,	,	PUNCT
biomedich-1001	194	18	allowing	allow	VERB
biomedich-1001	194	19	them	they	PRON
biomedich-1001	194	20	to	to	PART
biomedich-1001	194	21	play	play	VERB
biomedich-1001	194	22	a	a	DET
biomedich-1001	194	23	role	role	NOUN
biomedich-1001	194	24	in	in	ADP
biomedich-1001	194	25	the	the	DET
biomedich-1001	194	26	active	active	ADJ
biomedich-1001	194	27	site	site	NOUN
biomedich-1001	194	28	of	of	ADP
biomedich-1001	194	29	ligand	ligand	NOUN
biomedich-1001	194	30	-	-	PUNCT
biomedich-1001	194	31	receptor	receptor	NOUN
biomedich-1001	194	32	binding	binding	NOUN
biomedich-1001	194	33	.	.	PUNCT
biomedich-1001	195	1	meanwhile	meanwhile	ADV
biomedich-1001	195	2	,	,	PUNCT
biomedich-1001	195	3	amino	amino	NOUN
biomedich-1001	195	4	acid	acid	NOUN
biomedich-1001	195	5	residues	residue	NOUN
biomedich-1001	195	6	with	with	ADP
biomedich-1001	195	7	high	high	ADJ
biomedich-1001	195	8	fluctuation	fluctuation	NOUN
biomedich-1001	195	9	will	will	AUX
biomedich-1001	195	10	have	have	VERB
biomedich-1001	195	11	high	high	ADJ
biomedich-1001	195	12	flexibility	flexibility	NOUN
biomedich-1001	195	13	and	and	CCONJ
biomedich-1001	195	14	show	show	VERB
biomedich-1001	195	15	less	less	ADV
biomedich-1001	195	16	stable	stable	ADJ
biomedich-1001	195	17	interactions	interaction	NOUN
biomedich-1001	195	18	because	because	SCONJ
biomedich-1001	195	19	the	the	DET
biomedich-1001	195	20	position	position	NOUN
biomedich-1001	195	21	of	of	ADP
biomedich-1001	195	22	these	these	DET
biomedich-1001	195	23	amino	amino	ADJ
biomedich-1001	195	24	acids	acid	NOUN
biomedich-1001	195	25	undergoes	undergo	VERB
biomedich-1001	195	26	many	many	ADJ
biomedich-1001	195	27	changes	change	NOUN
biomedich-1001	195	28	during	during	ADP
biomedich-1001	195	29	dynamic	dynamic	ADJ
biomedich-1001	195	30	molecular	molecular	ADJ
biomedich-1001	195	31	simulation	simulation	NOUN
biomedich-1001	195	32	(	(	PUNCT
biomedich-1001	195	33	mardianingrum	mardianingrum	NOUN
biomedich-1001	195	34	et	et	PROPN
biomedich-1001	195	35	al	al	PROPN
biomedich-1001	195	36	.	.	PROPN
biomedich-1001	195	37	,	,	PUNCT
biomedich-1001	195	38	2021	2021	NUM
biomedich-1001	195	39	)	)	PUNCT
biomedich-1001	195	40	.	.	PUNCT
biomedich-1001	196	1	based	base	VERB
biomedich-1001	196	2	on	on	ADP
biomedich-1001	196	3	the	the	DET
biomedich-1001	196	4	analysis	analysis	NOUN
biomedich-1001	196	5	results	result	NOUN
biomedich-1001	196	6	,	,	PUNCT
biomedich-1001	196	7	glu802	glu802	ADJ
biomedich-1001	196	8	,	,	PUNCT
biomedich-1001	196	9	arg880	arg880	ADJ
biomedich-1001	196	10	,	,	PUNCT
biomedich-1001	196	11	and	and	CCONJ
biomedich-1001	196	12	thr1010	thr1010	NOUN
biomedich-1001	196	13	are	be	AUX
biomedich-1001	196	14	important	important	ADJ
biomedich-1001	196	15	amino	amino	NOUN
biomedich-1001	196	16	acid	acid	NOUN
biomedich-1001	196	17	residues	residue	NOUN
biomedich-1001	196	18	or	or	CCONJ
biomedich-1001	196	19	constitute	constitute	VERB
biomedich-1001	196	20	the	the	DET
biomedich-1001	196	21	binding	bind	VERB
biomedich-1001	196	22	active	active	ADJ
biomedich-1001	196	23	site	site	NOUN
biomedich-1001	196	24	in	in	ADP
biomedich-1001	196	25	the	the	DET
biomedich-1001	196	26	xanthine	xanthine	NOUN
biomedich-1001	196	27	oxidase	oxidase	NOUN
biomedich-1001	196	28	receptor	receptor	NOUN
biomedich-1001	196	29	.	.	PUNCT
biomedich-1001	197	1	figure	figure	NOUN
biomedich-1001	197	2	6	6	NUM
biomedich-1001	197	3	shows	show	VERB
biomedich-1001	197	4	that	that	SCONJ
biomedich-1001	197	5	the	the	DET
biomedich-1001	197	6	residues	residue	NOUN
biomedich-1001	197	7	glu802	glu802	ADJ
biomedich-1001	197	8	,	,	PUNCT
biomedich-1001	197	9	arg880	arg880	ADJ
biomedich-1001	197	10	,	,	PUNCT
biomedich-1001	197	11	and	and	CCONJ
biomedich-1001	197	12	thr1010	thr1010	NOUN
biomedich-1001	197	13	have	have	VERB
biomedich-1001	197	14	low	low	ADJ
biomedich-1001	197	15	fluctuation	fluctuation	NOUN
biomedich-1001	197	16	and	and	CCONJ
biomedich-1001	197	17	do	do	AUX
biomedich-1001	197	18	not	not	PART
biomedich-1001	197	19	exhibit	exhibit	VERB
biomedich-1001	197	20	high	high	ADJ
biomedich-1001	197	21	flexibility	flexibility	NOUN
biomedich-1001	197	22	during	during	ADP
biomedich-1001	197	23	the	the	DET
biomedich-1001	197	24	simulation	simulation	NOUN
biomedich-1001	197	25	process	process	NOUN
biomedich-1001	197	26	.	.	PUNCT
biomedich-1001	198	1	hence	hence	ADV
biomedich-1001	198	2	,	,	PUNCT
biomedich-1001	198	3	it	it	PRON
biomedich-1001	198	4	can	can	AUX
biomedich-1001	198	5	be	be	AUX
biomedich-1001	198	6	said	say	VERB
biomedich-1001	198	7	that	that	SCONJ
biomedich-1001	198	8	the	the	DET
biomedich-1001	198	9	test	test	NOUN
biomedich-1001	198	10	compound	compound	NOUN
biomedich-1001	198	11	can	can	AUX
biomedich-1001	198	12	provide	provide	VERB
biomedich-1001	198	13	activity	activity	NOUN
biomedich-1001	198	14	as	as	ADP
biomedich-1001	198	15	an	an	DET
biomedich-1001	198	16	antagonist	antagonist	NOUN
biomedich-1001	198	17	against	against	ADP
biomedich-1001	198	18	the	the	DET
biomedich-1001	198	19	xanthine	xanthine	NOUN
biomedich-1001	198	20	oxidase	oxidase	NOUN
biomedich-1001	198	21	receptor	receptor	NOUN
biomedich-1001	198	22	.	.	PUNCT
biomedich-1001	199	1	the	the	DET
biomedich-1001	199	2	compatibility	compatibility	NOUN
biomedich-1001	199	3	of	of	ADP
biomedich-1001	199	4	amino	amino	ADJ
biomedich-1001	199	5	acids	acid	NOUN
biomedich-1001	199	6	with	with	ADP
biomedich-1001	199	7	the	the	DET
biomedich-1001	199	8	comparative	comparative	ADJ
biomedich-1001	199	9	drug	drug	NOUN
biomedich-1001	199	10	is	be	AUX
biomedich-1001	199	11	one	one	NUM
biomedich-1001	199	12	of	of	ADP
biomedich-1001	199	13	the	the	DET
biomedich-1001	199	14	parameters	parameter	NOUN
biomedich-1001	199	15	in	in	ADP
biomedich-1001	199	16	molecular	molecular	ADJ
biomedich-1001	199	17	dynamic	dynamic	ADJ
biomedich-1001	199	18	studies	study	NOUN
biomedich-1001	199	19	.	.	PUNCT
biomedich-1001	200	1	the	the	DET
biomedich-1001	200	2	more	more	ADV
biomedich-1001	200	3	amino	amino	ADJ
biomedich-1001	200	4	acids	acid	NOUN
biomedich-1001	200	5	that	that	PRON
biomedich-1001	200	6	match	match	VERB
biomedich-1001	200	7	with	with	ADP
biomedich-1001	200	8	the	the	DET
biomedich-1001	200	9	comparative	comparative	ADJ
biomedich-1001	200	10	drug	drug	NOUN
biomedich-1001	200	11	,	,	PUNCT
biomedich-1001	200	12	it	it	PRON
biomedich-1001	200	13	can	can	AUX
biomedich-1001	200	14	be	be	AUX
biomedich-1001	200	15	assumed	assume	VERB
biomedich-1001	200	16	that	that	SCONJ
biomedich-1001	200	17	the	the	DET
biomedich-1001	200	18	compound	compound	NOUN
biomedich-1001	200	19	has	have	VERB
biomedich-1001	200	20	an	an	DET
biomedich-1001	200	21	inhibitory	inhibitory	ADJ
biomedich-1001	200	22	ability	ability	NOUN
biomedich-1001	200	23	that	that	PRON
biomedich-1001	200	24	is	be	AUX
biomedich-1001	200	25	almost	almost	ADV
biomedich-1001	200	26	the	the	DET
biomedich-1001	200	27	same	same	ADJ
biomedich-1001	200	28	or	or	CCONJ
biomedich-1001	200	29	even	even	ADV
biomedich-1001	200	30	better	well	ADJ
biomedich-1001	200	31	than	than	ADP
biomedich-1001	200	32	that	that	PRON
biomedich-1001	200	33	of	of	ADP
biomedich-1001	200	34	the	the	DET
biomedich-1001	200	35	comparative	comparative	ADJ
biomedich-1001	200	36	drug	drug	NOUN
biomedich-1001	200	37	(	(	PUNCT
biomedich-1001	200	38	frimayanti	frimayanti	NOUN
biomedich-1001	200	39	et	et	PROPN
biomedich-1001	200	40	al	al	PROPN
biomedich-1001	200	41	.	.	PROPN
biomedich-1001	200	42	,	,	PUNCT
biomedich-1001	200	43	2021	2021	NUM
biomedich-1001	200	44	)	)	PUNCT
biomedich-1001	200	45	.	.	PUNCT
biomedich-1001	201	1	in	in	ADP
biomedich-1001	201	2	addition	addition	NOUN
biomedich-1001	201	3	to	to	ADP
biomedich-1001	201	4	the	the	DET
biomedich-1001	201	5	rmsd	rmsd	NOUN
biomedich-1001	201	6	and	and	CCONJ
biomedich-1001	201	7	rmsf	rmsf	NOUN
biomedich-1001	201	8	plots	plot	NOUN
biomedich-1001	201	9	,	,	PUNCT
biomedich-1001	201	10	the	the	DET
biomedich-1001	201	11	stability	stability	NOUN
biomedich-1001	201	12	of	of	ADP
biomedich-1001	201	13	the	the	DET
biomedich-1001	201	14	compound	compound	NOUN
biomedich-1001	201	15	is	be	AUX
biomedich-1001	201	16	also	also	ADV
biomedich-1001	201	17	supported	support	VERB
biomedich-1001	201	18	by	by	ADP
biomedich-1001	201	19	the	the	DET
biomedich-1001	201	20	interactions	interaction	NOUN
biomedich-1001	201	21	between	between	ADP
biomedich-1001	201	22	the	the	DET
biomedich-1001	201	23	compound	compound	NOUN
biomedich-1001	201	24	and	and	CCONJ
biomedich-1001	201	25	the	the	DET
biomedich-1001	201	26	receptor	receptor	NOUN
biomedich-1001	201	27	.	.	PUNCT
biomedich-1001	202	1	based	base	VERB
biomedich-1001	202	2	on	on	ADP
biomedich-1001	202	3	the	the	DET
biomedich-1001	202	4	analysis	analysis	NOUN
biomedich-1001	202	5	results	result	NOUN
biomedich-1001	202	6	in	in	ADP
biomedich-1001	202	7	table	table	NOUN
biomedich-1001	202	8	6	6	NUM
biomedich-1001	202	9	,	,	PUNCT
biomedich-1001	202	10	the	the	DET
biomedich-1001	202	11	compound	compound	NOUN
biomedich-1001	202	12	5	5	NUM
biomedich-1001	202	13	-	-	SYM
biomedich-1001	202	14	hydroxy-3,7,4'-trimethoxyflavone	hydroxy-3,7,4'-trimethoxyflavone	NOUN
biomedich-1001	202	15	has	have	VERB
biomedich-1001	202	16	2	2	NUM
biomedich-1001	202	17	amino	amino	NOUN
biomedich-1001	202	18	acid	acid	NOUN
biomedich-1001	202	19	similarities	similarity	NOUN
biomedich-1001	202	20	with	with	ADP
biomedich-1001	202	21	allopurinol	allopurinol	NOUN
biomedich-1001	202	22	as	as	ADP
biomedich-1001	202	23	a	a	DET
biomedich-1001	202	24	comparison	comparison	NOUN
biomedich-1001	202	25	,	,	PUNCT
biomedich-1001	202	26	which	which	PRON
biomedich-1001	202	27	are	be	AUX
biomedich-1001	202	28	glu802	glu802	PROPN
biomedich-1001	202	29	and	and	CCONJ
biomedich-1001	202	30	ser876	ser876	NOUN
biomedich-1001	202	31	.	.	PUNCT
biomedich-1001	203	1	meanwhile	meanwhile	ADV
biomedich-1001	203	2	,	,	PUNCT
biomedich-1001	203	3	the	the	DET
biomedich-1001	203	4	compound	compound	NOUN
biomedich-1001	203	5	kaempferol	kaempferol	NOUN
biomedich-1001	203	6	has	have	VERB
biomedich-1001	203	7	3	3	NUM
biomedich-1001	203	8	amino	amino	NOUN
biomedich-1001	203	9	acid	acid	NOUN
biomedich-1001	203	10	similarities	similarity	NOUN
biomedich-1001	203	11	with	with	ADP
biomedich-1001	203	12	allopurinol	allopurinol	NOUN
biomedich-1001	203	13	,	,	PUNCT
biomedich-1001	203	14	namely	namely	ADV
biomedich-1001	203	15	thr1010	thr1010	NOUN
biomedich-1001	203	16	,	,	PUNCT
biomedich-1001	203	17	val1011	val1011	NOUN
biomedich-1001	203	18	,	,	PUNCT
biomedich-1001	203	19	and	and	CCONJ
biomedich-1001	203	20	ala1078	ala1078	ADJ
biomedich-1001	203	21	.	.	PUNCT
biomedich-1001	204	1	based	base	VERB
biomedich-1001	204	2	on	on	ADP
biomedich-1001	204	3	this	this	PRON
biomedich-1001	204	4	,	,	PUNCT
biomedich-1001	204	5	the	the	DET
biomedich-1001	204	6	compound	compound	NOUN
biomedich-1001	204	7	kaempferol	kaempferol	NOUN
biomedich-1001	204	8	has	have	VERB
biomedich-1001	204	9	the	the	DET
biomedich-1001	204	10	potential	potential	NOUN
biomedich-1001	204	11	to	to	PART
biomedich-1001	204	12	be	be	AUX
biomedich-1001	204	13	a	a	DET
biomedich-1001	204	14	candidate	candidate	NOUN
biomedich-1001	204	15	for	for	ADP
biomedich-1001	204	16	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	204	17	drugs	drug	NOUN
biomedich-1001	204	18	and	and	CCONJ
biomedich-1001	204	19	is	be	AUX
biomedich-1001	204	20	assumed	assume	VERB
biomedich-1001	204	21	to	to	PART
biomedich-1001	204	22	be	be	AUX
biomedich-1001	204	23	able	able	ADJ
biomedich-1001	204	24	to	to	PART
biomedich-1001	204	25	bind	bind	VERB
biomedich-1001	204	26	to	to	ADP
biomedich-1001	204	27	receptors	receptor	NOUN
biomedich-1001	204	28	and	and	CCONJ
biomedich-1001	204	29	be	be	AUX
biomedich-1001	204	30	stable	stable	ADJ
biomedich-1001	204	31	due	due	ADP
biomedich-1001	204	32	to	to	ADP
biomedich-1001	204	33	having	have	VERB
biomedich-1001	204	34	many	many	ADJ
biomedich-1001	204	35	amino	amino	NOUN
biomedich-1001	204	36	acid	acid	NOUN
biomedich-1001	204	37	similarities	similarity	NOUN
biomedich-1001	204	38	with	with	ADP
biomedich-1001	204	39	allopurinol	allopurinol	NOUN
biomedich-1001	204	40	as	as	ADP
biomedich-1001	204	41	a	a	DET
biomedich-1001	204	42	comparative	comparative	ADJ
biomedich-1001	204	43	drug	drug	NOUN
biomedich-1001	204	44	.	.	PUNCT
biomedich-1001	205	1	conclusion	conclusion	NOUN
biomedich-1001	205	2	the	the	DET
biomedich-1001	205	3	compound	compound	NOUN
biomedich-1001	205	4	with	with	ADP
biomedich-1001	205	5	the	the	DET
biomedich-1001	205	6	most	most	ADV
biomedich-1001	205	7	stable	stable	ADJ
biomedich-1001	205	8	interaction	interaction	NOUN
biomedich-1001	205	9	from	from	ADP
biomedich-1001	205	10	java	java	PROPN
biomedich-1001	205	11	cardamom	cardamom	PROPN
biomedich-1001	205	12	(	(	PUNCT
biomedich-1001	205	13	wurfbania	wurfbania	PROPN
biomedich-1001	205	14	compacta	compacta	NOUN
biomedich-1001	205	15	)	)	PUNCT
biomedich-1001	205	16	leaf	leaf	NOUN
biomedich-1001	205	17	with	with	ADP
biomedich-1001	205	18	receptors	receptor	NOUN
biomedich-1001	205	19	that	that	PRON
biomedich-1001	205	20	play	play	VERB
biomedich-1001	205	21	a	a	DET
biomedich-1001	205	22	role	role	NOUN
biomedich-1001	205	23	in	in	ADP
biomedich-1001	205	24	inhibiting	inhibit	VERB
biomedich-1001	205	25	xanthine	xanthine	NOUN
biomedich-1001	205	26	oxidase	oxidase	NOUN
biomedich-1001	205	27	enzyme	enzyme	NOUN
biomedich-1001	205	28	in	in	ADP
biomedich-1001	205	29	silico	silico	NOUN
biomedich-1001	205	30	is	be	AUX
biomedich-1001	205	31	the	the	DET
biomedich-1001	205	32	compound	compound	NOUN
biomedich-1001	205	33	kaempferol	kaempferol	NOUN
biomedich-1001	205	34	with	with	ADP
biomedich-1001	205	35	a	a	DET
biomedich-1001	205	36	binding	bind	VERB
biomedich-1001	205	37	energy	energy	NOUN
biomedich-1001	205	38	value	value	NOUN
biomedich-1001	205	39	of	of	ADP
biomedich-1001	205	40	-8.1	-8.1	PROPN
biomedich-1001	205	41	kcal	kcal	PROPN
biomedich-1001	205	42	/	/	SYM
biomedich-1001	205	43	mol	mol	PROPN
biomedich-1001	205	44	and	and	CCONJ
biomedich-1001	205	45	ki	ki	PROPN
biomedich-1001	205	46	1.15	1.15	NUM
biomedich-1001	205	47	um	um	INTJ
biomedich-1001	205	48	(	(	PUNCT
biomedich-1001	205	49	micromolar	micromolar	NOUN
biomedich-1001	205	50	)	)	PUNCT
biomedich-1001	205	51	.	.	PUNCT
biomedich-1001	206	1	kaempferol	kaempferol	NOUN
biomedich-1001	206	2	has	have	VERB
biomedich-1001	206	3	a	a	DET
biomedich-1001	206	4	stable	stable	ADJ
biomedich-1001	206	5	interaction	interaction	NOUN
biomedich-1001	206	6	based	base	VERB
biomedich-1001	206	7	on	on	ADP
biomedich-1001	206	8	rmsd	rmsd	NOUN
biomedich-1001	206	9	and	and	CCONJ
biomedich-1001	206	10	rmsf	rmsf	VERB
biomedich-1001	206	11	analysis	analysis	NOUN
biomedich-1001	206	12	and	and	CCONJ
biomedich-1001	206	13	shares	share	NOUN
biomedich-1001	206	14	three	three	NUM
biomedich-1001	206	15	amino	amino	ADJ
biomedich-1001	206	16	acids	acid	NOUN
biomedich-1001	206	17	with	with	ADP
biomedich-1001	206	18	allopurinol	allopurinol	NOUN
biomedich-1001	206	19	,	,	PUNCT
biomedich-1001	206	20	namely	namely	ADV
biomedich-1001	206	21	thr1010	thr1010	NOUN
biomedich-1001	206	22	,	,	PUNCT
biomedich-1001	206	23	val1011	val1011	NOUN
biomedich-1001	206	24	,	,	PUNCT
biomedich-1001	206	25	and	and	CCONJ
biomedich-1001	206	26	ala1078	ala1078	ADJ
biomedich-1001	206	27	,	,	PUNCT
biomedich-1001	206	28	so	so	SCONJ
biomedich-1001	206	29	it	it	PRON
biomedich-1001	206	30	can	can	AUX
biomedich-1001	206	31	be	be	AUX
biomedich-1001	206	32	said	say	VERB
biomedich-1001	206	33	to	to	PART
biomedich-1001	206	34	have	have	VERB
biomedich-1001	206	35	potential	potential	NOUN
biomedich-1001	206	36	as	as	ADP
biomedich-1001	206	37	a	a	DET
biomedich-1001	206	38	candidate	candidate	NOUN
biomedich-1001	206	39	for	for	ADP
biomedich-1001	206	40	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	206	41	drugs	drug	NOUN
biomedich-1001	206	42	.	.	PUNCT
biomedich-1001	207	1	therefore	therefore	ADV
biomedich-1001	207	2	,	,	PUNCT
biomedich-1001	207	3	further	further	ADJ
biomedich-1001	207	4	research	research	NOUN
biomedich-1001	207	5	related	relate	VERB
biomedich-1001	207	6	to	to	ADP
biomedich-1001	207	7	in	in	ADP
biomedich-1001	207	8	vitro	vitro	X
biomedich-1001	207	9	and	and	CCONJ
biomedich-1001	207	10	in	in	ADP
biomedich-1001	207	11	vivo	vivo	NOUN
biomedich-1001	207	12	tests	test	NOUN
biomedich-1001	207	13	needs	need	VERB
biomedich-1001	207	14	to	to	PART
biomedich-1001	207	15	be	be	AUX
biomedich-1001	207	16	carried	carry	VERB
biomedich-1001	207	17	out	out	ADP
biomedich-1001	207	18	to	to	PART
biomedich-1001	207	19	determine	determine	VERB
biomedich-1001	207	20	the	the	DET
biomedich-1001	207	21	actual	actual	ADJ
biomedich-1001	207	22	biological	biological	ADJ
biomedich-1001	207	23	conditions	condition	NOUN
biomedich-1001	207	24	that	that	PRON
biomedich-1001	207	25	occur	occur	VERB
biomedich-1001	207	26	in	in	ADP
biomedich-1001	207	27	the	the	DET
biomedich-1001	207	28	body	body	NOUN
biomedich-1001	207	29	before	before	ADP
biomedich-1001	207	30	binding	bind	VERB
biomedich-1001	207	31	to	to	ADP
biomedich-1001	207	32	the	the	DET
biomedich-1001	207	33	target	target	NOUN
biomedich-1001	207	34	receptor	receptor	NOUN
biomedich-1001	207	35	that	that	PRON
biomedich-1001	207	36	causes	cause	VERB
biomedich-1001	207	37	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	207	38	.	.	PUNCT
biomedich-1001	208	1	acknowledgements	acknowledgement	NOUN
biomedich-1001	208	2	:	:	PUNCT
biomedich-1001	208	3	the	the	DET
biomedich-1001	208	4	authors	author	NOUN
biomedich-1001	208	5	gratefully	gratefully	ADV
biomedich-1001	208	6	acknowledge	acknowledge	VERB
biomedich-1001	208	7	the	the	DET
biomedich-1001	208	8	support	support	NOUN
biomedich-1001	208	9	of	of	ADP
biomedich-1001	208	10	ministry	ministry	PROPN
biomedich-1001	208	11	of	of	ADP
biomedich-1001	208	12	education	education	NOUN
biomedich-1001	208	13	and	and	CCONJ
biomedich-1001	208	14	culture	culture	NOUN
biomedich-1001	208	15	in	in	ADP
biomedich-1001	208	16	providing	provide	VERB
biomedich-1001	208	17	funds	fund	NOUN
biomedich-1001	208	18	.	.	PUNCT
biomedich-1001	209	1	we	we	PRON
biomedich-1001	209	2	also	also	ADV
biomedich-1001	209	3	thank	thank	VERB
biomedich-1001	209	4	the	the	DET
biomedich-1001	209	5	research	research	NOUN
biomedich-1001	209	6	team	team	NOUN
biomedich-1001	209	7	and	and	CCONJ
biomedich-1001	209	8	perjuangan	perjuangan	PROPN
biomedich-1001	209	9	university	university	PROPN
biomedich-1001	209	10	of	of	ADP
biomedich-1001	209	11	tasikmalaya	tasikmalaya	NOUN
biomedich-1001	209	12	for	for	ADP
biomedich-1001	209	13	their	their	PRON
biomedich-1001	209	14	support	support	NOUN
biomedich-1001	209	15	.	.	PUNCT
biomedich-1001	210	1	authors	author	NOUN
biomedich-1001	210	2	’	'	PUNCT
biomedich-1001	210	3	contributions	contribution	NOUN
biomedich-1001	210	4	:	:	PUNCT
biomedich-1001	210	5	ali	ali	PROPN
biomedich-1001	210	6	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	210	7	designed	design	VERB
biomedich-1001	210	8	the	the	DET
biomedich-1001	210	9	study	study	NOUN
biomedich-1001	210	10	.	.	PUNCT
biomedich-1001	211	1	nitya	nitya	PROPN
biomedich-1001	211	2	nurul	nurul	PROPN
biomedich-1001	211	3	fadilah	fadilah	PROPN
biomedich-1001	211	4	&	&	CCONJ
biomedich-1001	211	5	selvy	selvy	PROPN
biomedich-1001	211	6	isnaeni	isnaeni	PROPN
biomedich-1001	211	7	carried	carry	VERB
biomedich-1001	211	8	out	out	ADP
biomedich-1001	211	9	the	the	DET
biomedich-1001	211	10	laboratory	laboratory	NOUN
biomedich-1001	211	11	work	work	NOUN
biomedich-1001	211	12	.	.	PUNCT
biomedich-1001	212	1	ali	ali	PROPN
biomedich-1001	212	2	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	212	3	analyzed	analyze	VERB
biomedich-1001	212	4	the	the	DET
biomedich-1001	212	5	data	datum	NOUN
biomedich-1001	212	6	and	and	CCONJ
biomedich-1001	212	7	wrote	write	VERB
biomedich-1001	212	8	the	the	DET
biomedich-1001	212	9	manuscript	manuscript	NOUN
biomedich-1001	212	10	.	.	PUNCT
biomedich-1001	213	1	all	all	DET
biomedich-1001	213	2	authors	author	NOUN
biomedich-1001	213	3	read	read	VERB
biomedich-1001	213	4	and	and	CCONJ
biomedich-1001	213	5	approved	approve	VERB
biomedich-1001	213	6	the	the	DET
biomedich-1001	213	7	final	final	ADJ
biomedich-1001	213	8	version	version	NOUN
biomedich-1001	213	9	of	of	ADP
biomedich-1001	213	10	the	the	DET
biomedich-1001	213	11	manuscript	manuscript	NOUN
biomedich-1001	213	12	competing	compete	VERB
biomedich-1001	213	13	interests	interest	NOUN
biomedich-1001	213	14	:	:	PUNCT
biomedich-1001	213	15	the	the	DET
biomedich-1001	213	16	authors	author	NOUN
biomedich-1001	213	17	declare	declare	VERB
biomedich-1001	213	18	that	that	SCONJ
biomedich-1001	213	19	there	there	PRON
biomedich-1001	213	20	are	be	VERB
biomedich-1001	213	21	no	no	DET
biomedich-1001	213	22	competing	compete	VERB
biomedich-1001	213	23	interests	interest	NOUN
biomedich-1001	213	24	.	.	PUNCT
biomedich-1001	214	1	funding	funding	NOUN
biomedich-1001	214	2	:	:	PUNCT
biomedich-1001	214	3	this	this	DET
biomedich-1001	214	4	funding	funding	NOUN
biomedich-1001	214	5	is	be	AUX
biomedich-1001	214	6	provided	provide	VERB
biomedich-1001	214	7	by	by	ADP
biomedich-1001	214	8	the	the	DET
biomedich-1001	214	9	ministry	ministry	PROPN
biomedich-1001	214	10	of	of	ADP
biomedich-1001	214	11	education	education	PROPN
biomedich-1001	214	12	and	and	CCONJ
biomedich-1001	214	13	culture	culture	NOUN
biomedich-1001	214	14	under	under	ADP
biomedich-1001	214	15	the	the	DET
biomedich-1001	214	16	fundamental	fundamental	ADJ
biomedich-1001	214	17	research	research	NOUN
biomedich-1001	214	18	scheme	scheme	NOUN
biomedich-1001	214	19	.	.	PUNCT
biomedich-1001	215	1	references	reference	NOUN
biomedich-1001	215	2	chintha	chintha	PROPN
biomedich-1001	215	3	,	,	PUNCT
biomedich-1001	215	4	c.	c.	PROPN
biomedich-1001	215	5	,	,	PUNCT
biomedich-1001	215	6	carlesso	carlesso	NOUN
biomedich-1001	215	7	,	,	PUNCT
biomedich-1001	215	8	a.	a.	NOUN
biomedich-1001	215	9	,	,	PUNCT
biomedich-1001	215	10	gorman	gorman	NOUN
biomedich-1001	215	11	,	,	PUNCT
biomedich-1001	215	12	a.	a.	NOUN
biomedich-1001	215	13	m.	m.	NOUN
biomedich-1001	215	14	,	,	PUNCT
biomedich-1001	215	15	samali	samali	PROPN
biomedich-1001	215	16	,	,	PUNCT
biomedich-1001	215	17	a.	a.	PROPN
biomedich-1001	215	18	,	,	PUNCT
biomedich-1001	215	19	&	&	CCONJ
biomedich-1001	215	20	eriksson	eriksson	PROPN
biomedich-1001	215	21	,	,	PUNCT
biomedich-1001	215	22	l.	l.	PROPN
biomedich-1001	215	23	a.	a.	PROPN
biomedich-1001	215	24	(	(	PUNCT
biomedich-1001	215	25	2020	2020	NUM
biomedich-1001	215	26	)	)	PUNCT
biomedich-1001	215	27	.	.	PUNCT
biomedich-1001	216	1	molecular	molecular	ADJ
biomedich-1001	216	2	modeling	modeling	NOUN
biomedich-1001	216	3	provides	provide	VERB
biomedich-1001	216	4	a	a	DET
biomedich-1001	216	5	structural	structural	ADJ
biomedich-1001	216	6	basis	basis	NOUN
biomedich-1001	216	7	for	for	ADP
biomedich-1001	216	8	perk	perk	ADJ
biomedich-1001	216	9	inhibitor	inhibitor	NOUN
biomedich-1001	216	10	selectivity	selectivity	NOUN
biomedich-1001	216	11	towards	towards	ADP
biomedich-1001	216	12	ripk1	ripk1	NOUN
biomedich-1001	216	13	.	.	PUNCT
biomedich-1001	217	1	rsc	rsc	PROPN
biomedich-1001	217	2	advances	advance	NOUN
biomedich-1001	217	3	,	,	PUNCT
biomedich-1001	217	4	10(1	10(1	NUM
biomedich-1001	217	5	)	)	PUNCT
biomedich-1001	217	6	,	,	PUNCT
biomedich-1001	217	7	367–375	367–375	NUM
biomedich-1001	217	8	.	.	PUNCT
biomedich-1001	218	1	https://doi.org/10.1039/c9ra08047c	https://doi.org/10.1039/c9ra08047c	PROPN
biomedich-1001	218	2	dari	dari	PROPN
biomedich-1001	218	3	,	,	PUNCT
biomedich-1001	218	4	d.	d.	PROPN
biomedich-1001	218	5	w.	w.	PROPN
biomedich-1001	218	6	(	(	PUNCT
biomedich-1001	218	7	2022	2022	NUM
biomedich-1001	218	8	)	)	PUNCT
biomedich-1001	218	9	.	.	PUNCT
biomedich-1001	219	1	uji	uji	PROPN
biomedich-1001	219	2	potensi	potensi	PROPN
biomedich-1001	219	3	senyawa	senyawa	PROPN
biomedich-1001	219	4	metabolit	metabolit	VERB
biomedich-1001	219	5	sekunder	sekunder	NOUN
biomedich-1001	219	6	tanaman	tanaman	PROPN
biomedich-1001	219	7	putri	putri	PROPN
biomedich-1001	219	8	malu	malu	PROPN
biomedich-1001	219	9	(	(	PUNCT
biomedich-1001	219	10	mimosa	mimosa	PROPN
biomedich-1001	219	11	pudica	pudica	PROPN
biomedich-1001	219	12	l.	l.	PROPN
biomedich-1001	219	13	)	)	PUNCT
biomedich-1001	219	14	sebagai	sebagai	PROPN
biomedich-1001	219	15	inhibitor	inhibitor	NOUN
biomedich-1001	219	16	xanthine	xanthine	PROPN
biomedich-1001	219	17	oxidase	oxidase	NOUN
biomedich-1001	219	18	secara	secara	PROPN
biomedich-1001	219	19	in	in	ADP
biomedich-1001	219	20	silico	silico	NOUN
biomedich-1001	219	21	.	.	PUNCT
biomedich-1001	220	1	jurnal	jurnal	ADJ
biomedich-1001	220	2	ilmu	ilmu	PROPN
biomedich-1001	220	3	kefarmasian	kefarmasian	PROPN
biomedich-1001	220	4	,	,	PUNCT
biomedich-1001	220	5	3(2	3(2	NUM
biomedich-1001	220	6	)	)	PUNCT
biomedich-1001	220	7	.	.	PUNCT
biomedich-1001	221	1	dermawan	dermawan	NOUN
biomedich-1001	221	2	,	,	PUNCT
biomedich-1001	221	3	d.	d.	PROPN
biomedich-1001	221	4	,	,	PUNCT
biomedich-1001	221	5	sumirtanurdin	sumirtanurdin	PROPN
biomedich-1001	221	6	,	,	PUNCT
biomedich-1001	221	7	r.	r.	PROPN
biomedich-1001	221	8	,	,	PUNCT
biomedich-1001	221	9	&	&	CCONJ
biomedich-1001	221	10	dewantisari	dewantisari	PROPN
biomedich-1001	221	11	,	,	PUNCT
biomedich-1001	221	12	d.	d.	PROPN
biomedich-1001	221	13	(	(	PUNCT
biomedich-1001	221	14	2019	2019	NUM
biomedich-1001	221	15	)	)	PUNCT
biomedich-1001	221	16	.	.	PUNCT
biomedich-1001	222	1	molecular	molecular	ADJ
biomedich-1001	222	2	dynamics	dynamic	NOUN
biomedich-1001	222	3	simulation	simulation	NOUN
biomedich-1001	222	4	of	of	ADP
biomedich-1001	222	5	estrogen	estrogen	NOUN
biomedich-1001	222	6	receptor	receptor	NOUN
biomedich-1001	222	7	alpha	alpha	NOUN
biomedich-1001	222	8	against	against	ADP
biomedich-1001	222	9	andrografolid	andrografolid	NOUN
biomedich-1001	222	10	as	as	ADP
biomedich-1001	222	11	anti	anti	ADJ
biomedich-1001	222	12	breast	breast	NOUN
biomedich-1001	222	13	cancer	cancer	NOUN
biomedich-1001	222	14	.	.	PUNCT
biomedich-1001	223	1	indonesian	indonesian	ADJ
biomedich-1001	223	2	journal	journal	PROPN
biomedich-1001	223	3	of	of	ADP
biomedich-1001	223	4	pharmaceutical	pharmaceutical	NOUN
biomedich-1001	223	5	science	science	NOUN
biomedich-1001	223	6	and	and	CCONJ
biomedich-1001	223	7	technology	technology	NOUN
biomedich-1001	223	8	,	,	PUNCT
biomedich-1001	223	9	65–76	65–76	NUM
biomedich-1001	223	10	.	.	PUNCT
biomedich-1001	224	1	https://doi.org/10.24198/ijpst.v6i2.18168	https://doi.org/10.24198/ijpst.v6i2.18168	NOUN
biomedich-1001	224	2	dirgantara	dirgantara	PROPN
biomedich-1001	224	3	,	,	PUNCT
biomedich-1001	224	4	s.	s.	PROPN
biomedich-1001	224	5	,	,	PUNCT
biomedich-1001	224	6	insanu	insanu	NOUN
biomedich-1001	224	7	,	,	PUNCT
biomedich-1001	224	8	m.	m.	NOUN
biomedich-1001	224	9	,	,	PUNCT
biomedich-1001	224	10	&	&	CCONJ
biomedich-1001	224	11	fidrianny	fidrianny	PROPN
biomedich-1001	224	12	,	,	PUNCT
biomedich-1001	224	13	i.	i.	PROPN
biomedich-1001	224	14	(	(	PUNCT
biomedich-1001	224	15	2022	2022	NUM
biomedich-1001	224	16	)	)	PUNCT
biomedich-1001	224	17	.	.	PUNCT
biomedich-1001	225	1	evaluation	evaluation	NOUN
biomedich-1001	225	2	of	of	ADP
biomedich-1001	225	3	xanthine	xanthine	NOUN
biomedich-1001	225	4	oxidase	oxidase	NOUN
biomedich-1001	225	5	inhibitory	inhibitory	NOUN
biomedich-1001	225	6	,	,	PUNCT
biomedich-1001	225	7	antioxidative	antioxidative	ADJ
biomedich-1001	225	8	activity	activity	NOUN
biomedich-1001	225	9	of	of	ADP
biomedich-1001	225	10	five	five	NUM
biomedich-1001	225	11	selected	select	VERB
biomedich-1001	225	12	papua	papua	PROPN
biomedich-1001	225	13	medicinal	medicinal	ADJ
biomedich-1001	225	14	plants	plant	NOUN
biomedich-1001	225	15	and	and	CCONJ
biomedich-1001	225	16	correlation	correlation	NOUN
biomedich-1001	225	17	with	with	ADP
biomedich-1001	225	18	phytochemical	phytochemical	ADJ
biomedich-1001	225	19	content	content	NOUN
biomedich-1001	225	20	.	.	PUNCT
biomedich-1001	226	1	pharmacia	pharmacia	PROPN
biomedich-1001	226	2	,	,	PUNCT
biomedich-1001	226	3	69(4	69(4	NOUN
biomedich-1001	226	4	)	)	PUNCT
biomedich-1001	226	5	,	,	PUNCT
biomedich-1001	226	6	965–972	965–972	NUM
biomedich-1001	226	7	.	.	PUNCT
biomedich-1001	226	8	https://doi.org/10.3897/pharmacia.69.e91083	https://doi.org/10.3897/pharmacia.69.e91083	PUNCT
biomedich-1001	226	9	du	du	PROPN
biomedich-1001	226	10	,	,	PUNCT
biomedich-1001	226	11	l.	l.	PROPN
biomedich-1001	226	12	,	,	PUNCT
biomedich-1001	226	13	zong	zong	PROPN
biomedich-1001	226	14	,	,	PUNCT
biomedich-1001	226	15	y.	y.	PROPN
biomedich-1001	226	16	,	,	PUNCT
biomedich-1001	226	17	li	li	PROPN
biomedich-1001	226	18	,	,	PUNCT
biomedich-1001	226	19	h.	h.	PROPN
biomedich-1001	226	20	,	,	PUNCT
biomedich-1001	226	21	wang	wang	PROPN
biomedich-1001	226	22	,	,	PUNCT
biomedich-1001	226	23	q.	q.	PROPN
biomedich-1001	226	24	,	,	PUNCT
biomedich-1001	226	25	xie	xie	PROPN
biomedich-1001	226	26	,	,	PUNCT
biomedich-1001	226	27	l.	l.	PROPN
biomedich-1001	226	28	,	,	PUNCT
biomedich-1001	226	29	yang	yang	PROPN
biomedich-1001	226	30	,	,	PUNCT
biomedich-1001	226	31	b.	b.	PROPN
biomedich-1001	226	32	,	,	PUNCT
biomedich-1001	226	33	pang	pang	NOUN
biomedich-1001	226	34	,	,	PUNCT
biomedich-1001	226	35	y.	y.	PROPN
biomedich-1001	226	36	,	,	PUNCT
biomedich-1001	226	37	zhang	zhang	PROPN
biomedich-1001	226	38	,	,	PUNCT
biomedich-1001	226	39	c.	c.	PROPN
biomedich-1001	226	40	,	,	PUNCT
biomedich-1001	226	41	zhong	zhong	PROPN
biomedich-1001	226	42	,	,	PUNCT
biomedich-1001	226	43	z.	z.	PROPN
biomedich-1001	226	44	,	,	PUNCT
biomedich-1001	226	45	&	&	CCONJ
biomedich-1001	226	46	gao	gao	PROPN
biomedich-1001	226	47	,	,	PUNCT
biomedich-1001	226	48	j.	j.	PROPN
biomedich-1001	226	49	(	(	PUNCT
biomedich-1001	226	50	2024	2024	NUM
biomedich-1001	226	51	)	)	PUNCT
biomedich-1001	226	52	.	.	PUNCT
biomedich-1001	227	1	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	227	2	and	and	CCONJ
biomedich-1001	227	3	its	its	PRON
biomedich-1001	227	4	related	related	ADJ
biomedich-1001	227	5	diseases	disease	NOUN
biomedich-1001	227	6	:	:	PUNCT
biomedich-1001	227	7	mechanisms	mechanism	NOUN
biomedich-1001	227	8	and	and	CCONJ
biomedich-1001	227	9	advances	advance	NOUN
biomedich-1001	227	10	in	in	ADP
biomedich-1001	227	11	therapy	therapy	NOUN
biomedich-1001	227	12	.	.	PUNCT
biomedich-1001	228	1	signal	signal	ADJ
biomedich-1001	228	2	transduction	transduction	NOUN
biomedich-1001	228	3	and	and	CCONJ
biomedich-1001	228	4	targeted	target	VERB
biomedich-1001	228	5	therapy	therapy	NOUN
biomedich-1001	228	6	,	,	PUNCT
biomedich-1001	228	7	9(1	9(1	NUM
biomedich-1001	228	8	)	)	PUNCT
biomedich-1001	228	9	,	,	PUNCT
biomedich-1001	228	10	212	212	NUM
biomedich-1001	228	11	.	.	PUNCT
biomedich-1001	229	1	https://doi.org/10.1038/s41392-024-01916-y	https://doi.org/10.1038/s41392-024-01916-y	PROPN
biomedich-1001	229	2	elis	elis	PROPN
biomedich-1001	229	3	nurul	nurul	PROPN
biomedich-1001	229	4	ikhlas	ikhlas	PROPN
biomedich-1001	229	5	,	,	PUNCT
biomedich-1001	229	6	lina	lina	PROPN
biomedich-1001	229	7	rahmawati	rahmawati	PROPN
biomedich-1001	229	8	rizkuloh	rizkuloh	PROPN
biomedich-1001	229	9	,	,	PUNCT
biomedich-1001	229	10	&	&	CCONJ
biomedich-1001	229	11	richa	richa	PROPN
biomedich-1001	229	12	mardianingrum	mardianingrum	PROPN
biomedich-1001	229	13	.	.	PUNCT
biomedich-1001	230	1	(	(	PUNCT
biomedich-1001	230	2	2023	2023	NUM
biomedich-1001	230	3	)	)	PUNCT
biomedich-1001	230	4	.	.	PUNCT
biomedich-1001	231	1	analisa	analisa	NOUN
biomedich-1001	231	2	in	in	ADP
biomedich-1001	231	3	silico	silico	NOUN
biomedich-1001	231	4	senyawa	senyawa	NOUN
biomedich-1001	231	5	biji	biji	PROPN
biomedich-1001	231	6	lada	lada	PROPN
biomedich-1001	231	7	hitam	hitam	PROPN
biomedich-1001	231	8	(	(	PUNCT
biomedich-1001	231	9	piper	piper	PROPN
biomedich-1001	231	10	nigrum	nigrum	PROPN
biomedich-1001	231	11	l.	l.	PROPN
biomedich-1001	231	12	)	)	PUNCT
biomedich-1001	231	13	terhadap	terhadap	PROPN
biomedich-1001	231	14	aktivitas	aktivitas	PROPN
biomedich-1001	231	15	antioksidan	antioksidan	PROPN
biomedich-1001	231	16	.	.	PUNCT
biomedich-1001	232	1	jurnal	jurnal	ADJ
biomedich-1001	232	2	riset	riset	PROPN
biomedich-1001	232	3	rumpun	rumpun	PROPN
biomedich-1001	232	4	ilmu	ilmu	PROPN
biomedich-1001	232	5	kesehatan	kesehatan	PROPN
biomedich-1001	232	6	,	,	PUNCT
biomedich-1001	232	7	2(2	2(2	NUM
biomedich-1001	232	8	)	)	PUNCT
biomedich-1001	232	9	,	,	PUNCT
biomedich-1001	232	10	301	301	NUM
biomedich-1001	232	11	–	–	PUNCT
biomedich-1001	232	12	321	321	NUM
biomedich-1001	232	13	.	.	PUNCT
biomedich-1001	233	1	https://doi.org/10.55606/jurrikes.v2i2.1815	https://doi.org/10.55606/jurrikes.v2i2.1815	NOUN
biomedich-1001	233	2	fakih	fakih	NOUN
biomedich-1001	233	3	,	,	PUNCT
biomedich-1001	233	4	t.	t.	NOUN
biomedich-1001	233	5	m.	m.	NOUN
biomedich-1001	233	6	,	,	PUNCT
biomedich-1001	233	7	wisnuwardhani	wisnuwardhani	PROPN
biomedich-1001	233	8	,	,	PUNCT
biomedich-1001	233	9	h.	h.	PROPN
biomedich-1001	233	10	a.	a.	PROPN
biomedich-1001	233	11	,	,	PUNCT
biomedich-1001	233	12	dewi	dewi	PROPN
biomedich-1001	233	13	,	,	PUNCT
biomedich-1001	233	14	m.	m.	PROPN
biomedich-1001	233	15	l.	l.	PROPN
biomedich-1001	233	16	,	,	PUNCT
biomedich-1001	233	17	ramadhan	ramadhan	PROPN
biomedich-1001	233	18	,	,	PUNCT
biomedich-1001	233	19	d.	d.	PROPN
biomedich-1001	233	20	s.	s.	PROPN
biomedich-1001	233	21	f.	f.	PROPN
biomedich-1001	233	22	,	,	PUNCT
biomedich-1001	233	23	hidayat	hidayat	PROPN
biomedich-1001	233	24	,	,	PUNCT
biomedich-1001	233	25	a.	a.	PROPN
biomedich-1001	233	26	f.	f.	PROPN
biomedich-1001	233	27	,	,	PUNCT
biomedich-1001	233	28	&	&	CCONJ
biomedich-1001	233	29	prayitno	prayitno	PROPN
biomedich-1001	233	30	,	,	PUNCT
biomedich-1001	233	31	r.	r.	PROPN
biomedich-1001	233	32	(	(	PUNCT
biomedich-1001	233	33	2021	2021	NUM
biomedich-1001	233	34	)	)	PUNCT
biomedich-1001	233	35	.	.	PUNCT
biomedich-1001	234	1	simulasi	simulasi	PROPN
biomedich-1001	234	2	dinamika	dinamika	PROPN
biomedich-1001	234	3	molekuler	molekuler	PROPN
biomedich-1001	234	4	senyawa	senyawa	PROPN
biomedich-1001	234	5	asam	asam	PROPN
biomedich-1001	234	6	ferulat	ferulat	PROPN
biomedich-1001	234	7	dan	dan	PROPN
biomedich-1001	234	8	turunannya	turunannya	PROPN
biomedich-1001	234	9	dari	dari	PROPN
biomedich-1001	234	10	kulit	kulit	PROPN
biomedich-1001	234	11	buah	buah	PROPN
biomedich-1001	234	12	nanas	nanas	PROPN
biomedich-1001	234	13	(	(	PUNCT
biomedich-1001	234	14	ananas	ananas	PROPN
biomedich-1001	234	15	comosus	comosus	PROPN
biomedich-1001	234	16	)	)	PUNCT
biomedich-1001	234	17	sebagai	sebagai	PROPN
biomedich-1001	234	18	inhibitor	inhibitor	PROPN
biomedich-1001	234	19	enzim	enzim	PROPN
biomedich-1001	234	20	tirosinase	tirosinase	PROPN
biomedich-1001	234	21	.	.	PUNCT
biomedich-1001	235	1	jurnal	jurnal	ADJ
biomedich-1001	235	2	sains	sains	PROPN
biomedich-1001	235	3	farmasi	farmasi	PROPN
biomedich-1001	235	4	&	&	CCONJ
biomedich-1001	235	5	klinis	klinis	PROPN
biomedich-1001	235	6	,	,	PUNCT
biomedich-1001	235	7	8(2	8(2	NUM
biomedich-1001	235	8	)	)	PUNCT
biomedich-1001	235	9	,	,	PUNCT
biomedich-1001	235	10	208	208	NUM
biomedich-1001	235	11	.	.	PUNCT
biomedich-1001	236	1	https://doi.org/10.25077/jsfk.8.2.208-220.2021	https://doi.org/10.25077/jsfk.8.2.208-220.2021	NOUN
biomedich-1001	236	2	faqiha	faqiha	NOUN
biomedich-1001	236	3	,	,	PUNCT
biomedich-1001	236	4	a.	a.	PROPN
biomedich-1001	236	5	f.	f.	PROPN
biomedich-1001	236	6	,	,	PUNCT
biomedich-1001	236	7	indrawijaya	indrawijaya	PROPN
biomedich-1001	236	8	,	,	PUNCT
biomedich-1001	236	9	y.	y.	PROPN
biomedich-1001	236	10	y.	y.	PROPN
biomedich-1001	236	11	a.	a.	PROPN
biomedich-1001	236	12	,	,	PUNCT
biomedich-1001	236	13	suryadinata	suryadinata	PROPN
biomedich-1001	236	14	,	,	PUNCT
biomedich-1001	236	15	a.	a.	NOUN
biomedich-1001	236	16	,	,	PUNCT
biomedich-1001	236	17	amiruddin	amiruddin	PROPN
biomedich-1001	236	18	,	,	PUNCT
biomedich-1001	236	19	m.	m.	NOUN
biomedich-1001	236	20	,	,	PUNCT
biomedich-1001	236	21	&	&	CCONJ
biomedich-1001	236	22	mutiah	mutiah	PROPN
biomedich-1001	236	23	,	,	PUNCT
biomedich-1001	236	24	r.	r.	PROPN
biomedich-1001	236	25	(	(	PUNCT
biomedich-1001	236	26	2022	2022	NUM
biomedich-1001	236	27	)	)	PUNCT
biomedich-1001	236	28	.	.	PUNCT
biomedich-1001	237	1	potensi	potensi	PROPN
biomedich-1001	237	2	senyawa	senyawa	PROPN
biomedich-1001	237	3	nitazoxanide	nitazoxanide	PROPN
biomedich-1001	237	4	dan	dan	PROPN
biomedich-1001	237	5	1256	1256	NUM
biomedich-1001	237	6	biology	biology	NOUN
biomedich-1001	237	7	,	,	PUNCT
biomedich-1001	237	8	medicine	medicine	NOUN
biomedich-1001	237	9	,	,	PUNCT
biomedich-1001	237	10	&	&	CCONJ
biomedich-1001	237	11	natural	natural	ADJ
biomedich-1001	237	12	product	product	NOUN
biomedich-1001	237	13	chemistry	chemistry	NOUN
biomedich-1001	237	14	14	14	NUM
biomedich-1001	237	15	(	(	PUNCT
biomedich-1001	237	16	2	2	NUM
biomedich-1001	237	17	)	)	PUNCT
biomedich-1001	237	18	,	,	PUNCT
biomedich-1001	237	19	2025	2025	NUM
biomedich-1001	237	20	:	:	PUNCT
biomedich-1001	237	21	1247	1247	NUM
biomedich-1001	237	22	-	-	SYM
biomedich-1001	237	23	1256	1256	NUM
biomedich-1001	237	24	arbidol	arbidol	VERB
biomedich-1001	237	25	sebagai	sebagai	PROPN
biomedich-1001	237	26	antivirus	antivirus	PROPN
biomedich-1001	237	27	sars	sars	PROPN
biomedich-1001	237	28	-	-	PUNCT
biomedich-1001	237	29	cov-2	cov-2	NOUN
biomedich-1001	237	30	terhadap	terhadap	PROPN
biomedich-1001	237	31	reseptor	reseptor	NOUN
biomedich-1001	237	32	nsp5	nsp5	PROPN
biomedich-1001	237	33	(	(	PUNCT
biomedich-1001	237	34	7bqy	7bqy	PROPN
biomedich-1001	237	35	dan	dan	NOUN
biomedich-1001	237	36	2gz7	2gz7	NUM
biomedich-1001	237	37	)	)	PUNCT
biomedich-1001	237	38	dan	dan	PROPN
biomedich-1001	237	39	ace2	ace2	PROPN
biomedich-1001	237	40	(	(	PUNCT
biomedich-1001	237	41	3d0	3d0	NUM
biomedich-1001	237	42	g	g	PROPN
biomedich-1001	237	43	dan	dan	PROPN
biomedich-1001	237	44	1r4l	1r4l	PROPN
biomedich-1001	237	45	)	)	PUNCT
biomedich-1001	237	46	.	.	PUNCT
biomedich-1001	238	1	journal	journal	NOUN
biomedich-1001	238	2	of	of	ADP
biomedich-1001	238	3	food	food	NOUN
biomedich-1001	238	4	and	and	CCONJ
biomedich-1001	238	5	pharmaceutical	pharmaceutical	NOUN
biomedich-1001	238	6	sciences	science	NOUN
biomedich-1001	238	7	,	,	PUNCT
biomedich-1001	238	8	570–583	570–583	NUM
biomedich-1001	238	9	.	.	PUNCT
biomedich-1001	239	1	https://doi.org/10.22146/jfps.3393	https://doi.org/10.22146/jfps.3393	PROPN
biomedich-1001	239	2	frimayanti	frimayanti	PROPN
biomedich-1001	239	3	,	,	PUNCT
biomedich-1001	239	4	n.	n.	NOUN
biomedich-1001	239	5	,	,	PUNCT
biomedich-1001	239	6	djohari	djohari	PROPN
biomedich-1001	239	7	,	,	PUNCT
biomedich-1001	239	8	m.	m.	NOUN
biomedich-1001	239	9	,	,	PUNCT
biomedich-1001	239	10	&	&	CCONJ
biomedich-1001	239	11	khusnah	khusnah	PROPN
biomedich-1001	239	12	,	,	PUNCT
biomedich-1001	239	13	a.	a.	PROPN
biomedich-1001	239	14	n.	n.	PROPN
biomedich-1001	239	15	(	(	PUNCT
biomedich-1001	239	16	2021	2021	NUM
biomedich-1001	239	17	)	)	PUNCT
biomedich-1001	239	18	.	.	PUNCT
biomedich-1001	240	1	molekular	molekular	ADJ
biomedich-1001	240	2	docking	docking	NOUN
biomedich-1001	240	3	senyawa	senyawa	NOUN
biomedich-1001	240	4	analog	analog	PROPN
biomedich-1001	240	5	kalkon	kalkon	PROPN
biomedich-1001	240	6	sebagai	sebagai	PROPN
biomedich-1001	240	7	inhibitor	inhibitor	PROPN
biomedich-1001	240	8	untuk	untuk	PROPN
biomedich-1001	240	9	sel	sel	PROPN
biomedich-1001	240	10	kanker	kanker	PROPN
biomedich-1001	240	11	paru	paru	PROPN
biomedich-1001	240	12	-	-	PUNCT
biomedich-1001	240	13	paru	paru	PROPN
biomedich-1001	240	14	a549	a549	PROPN
biomedich-1001	240	15	.	.	PUNCT
biomedich-1001	241	1	jurnal	jurnal	PROPN
biomedich-1001	241	2	ilmu	ilmu	PROPN
biomedich-1001	241	3	kefarmasian	kefarmasian	PROPN
biomedich-1001	241	4	indonesia	indonesia	PROPN
biomedich-1001	241	5	,	,	PUNCT
biomedich-1001	241	6	19(1	19(1	NUM
biomedich-1001	241	7	)	)	PUNCT
biomedich-1001	241	8	,	,	PUNCT
biomedich-1001	241	9	87	87	NUM
biomedich-1001	241	10	.	.	PUNCT
biomedich-1001	242	1	https://doi.org/10.35814/jifi.v19i1.765	https://doi.org/10.35814/jifi.v19i1.765	PROPN
biomedich-1001	242	2	kartika	kartika	PROPN
biomedich-1001	242	3	,	,	PUNCT
biomedich-1001	242	4	c.	c.	PROPN
biomedich-1001	242	5	,	,	PUNCT
biomedich-1001	242	6	&	&	CCONJ
biomedich-1001	242	7	ruswanto	ruswanto	PROPN
biomedich-1001	242	8	,	,	PUNCT
biomedich-1001	242	9	r.	r.	PROPN
biomedich-1001	242	10	(	(	PUNCT
biomedich-1001	242	11	2021	2021	NUM
biomedich-1001	242	12	)	)	PUNCT
biomedich-1001	242	13	.	.	PUNCT
biomedich-1001	243	1	studi	studi	PROPN
biomedich-1001	243	2	in	in	ADP
biomedich-1001	243	3	silico	silico	NOUN
biomedich-1001	243	4	perbandingan	perbandingan	NOUN
biomedich-1001	243	5	aktivitas	aktivita	NOUN
biomedich-1001	243	6	antikanker	antikanker	PROPN
biomedich-1001	243	7	payudara	payudara	PROPN
biomedich-1001	243	8	dari	dari	PROPN
biomedich-1001	243	9	senyawa	senyawa	PROPN
biomedich-1001	243	10	kuersetin	kuersetin	PROPN
biomedich-1001	243	11	dengan	dengan	PROPN
biomedich-1001	243	12	derivatisasi	derivatisasi	PROPN
biomedich-1001	243	13	kuersetin	kuersetin	PROPN
biomedich-1001	243	14	terhadap	terhadap	PROPN
biomedich-1001	243	15	protein	protein	NOUN
biomedich-1001	243	16	her-2	her-2	X
biomedich-1001	243	17	.	.	PUNCT
biomedich-1001	244	1	kelutur	kelutur	PROPN
biomedich-1001	244	2	,	,	PUNCT
biomedich-1001	244	3	f.	f.	PROPN
biomedich-1001	244	4	j.	j.	PROPN
biomedich-1001	244	5	,	,	PUNCT
biomedich-1001	244	6	mustarichie	mustarichie	PROPN
biomedich-1001	244	7	,	,	PUNCT
biomedich-1001	244	8	r.	r.	PROPN
biomedich-1001	244	9	,	,	PUNCT
biomedich-1001	244	10	&	&	CCONJ
biomedich-1001	244	11	umar	umar	PROPN
biomedich-1001	244	12	,	,	PUNCT
biomedich-1001	244	13	a.	a.	PROPN
biomedich-1001	244	14	k.	k.	PROPN
biomedich-1001	244	15	(	(	PUNCT
biomedich-1001	244	16	2020	2020	NUM
biomedich-1001	244	17	)	)	PUNCT
biomedich-1001	244	18	.	.	PUNCT
biomedich-1001	245	1	virtual	virtual	ADJ
biomedich-1001	245	2	screening	screening	NOUN
biomedich-1001	245	3	kandungan	kandungan	PROPN
biomedich-1001	245	4	senyawa	senyawa	PROPN
biomedich-1001	245	5	kipas	kipas	PROPN
biomedich-1001	245	6	laut	laut	PROPN
biomedich-1001	245	7	(	(	PUNCT
biomedich-1001	245	8	gorgonia	gorgonia	PROPN
biomedich-1001	245	9	mariae	mariae	PROPN
biomedich-1001	245	10	)	)	PUNCT
biomedich-1001	245	11	sebagai	sebagai	PROPN
biomedich-1001	245	12	antiasma	antiasma	PROPN
biomedich-1001	245	13	.	.	PUNCT
biomedich-1001	246	1	alchemy	alchemy	VERB
biomedich-1001	246	2	jurnal	jurnal	ADJ
biomedich-1001	246	3	penelitian	penelitian	PROPN
biomedich-1001	246	4	kimia	kimia	NOUN
biomedich-1001	246	5	,	,	PUNCT
biomedich-1001	246	6	16	16	NUM
biomedich-1001	246	7	.	.	PUNCT
biomedich-1001	246	8	https://doi.org/10.20961/alchemy.16.2.39965.199-210	https://doi.org/10.20961/alchemy.16.2.39965.199-210	PROPN
biomedich-1001	247	1	liu	liu	PROPN
biomedich-1001	247	2	,	,	PUNCT
biomedich-1001	247	3	n.	n.	PROPN
biomedich-1001	247	4	,	,	PUNCT
biomedich-1001	247	5	xu	xu	PROPN
biomedich-1001	247	6	,	,	PUNCT
biomedich-1001	247	7	h.	h.	PROPN
biomedich-1001	247	8	,	,	PUNCT
biomedich-1001	247	9	sun	sun	PROPN
biomedich-1001	247	10	,	,	PUNCT
biomedich-1001	247	11	q.	q.	PROPN
biomedich-1001	247	12	,	,	PUNCT
biomedich-1001	247	13	yu	yu	PROPN
biomedich-1001	247	14	,	,	PUNCT
biomedich-1001	247	15	x.	x.	PROPN
biomedich-1001	247	16	,	,	PUNCT
biomedich-1001	247	17	chen	chen	PROPN
biomedich-1001	247	18	,	,	PUNCT
biomedich-1001	247	19	w.	w.	PROPN
biomedich-1001	247	20	,	,	PUNCT
biomedich-1001	247	21	wei	wei	PROPN
biomedich-1001	247	22	,	,	PUNCT
biomedich-1001	247	23	h.	h.	PROPN
biomedich-1001	247	24	,	,	PUNCT
biomedich-1001	247	25	jiang	jiang	PROPN
biomedich-1001	247	26	,	,	PUNCT
biomedich-1001	247	27	j.	j.	PROPN
biomedich-1001	247	28	,	,	PUNCT
biomedich-1001	247	29	xu	xu	PROPN
biomedich-1001	247	30	,	,	PUNCT
biomedich-1001	247	31	y.	y.	PROPN
biomedich-1001	247	32	,	,	PUNCT
biomedich-1001	247	33	&	&	CCONJ
biomedich-1001	247	34	lu	lu	PROPN
biomedich-1001	247	35	,	,	PUNCT
biomedich-1001	247	36	w.	w.	PROPN
biomedich-1001	247	37	(	(	PUNCT
biomedich-1001	247	38	2021	2021	NUM
biomedich-1001	247	39	)	)	PUNCT
biomedich-1001	247	40	.	.	PUNCT
biomedich-1001	248	1	the	the	DET
biomedich-1001	248	2	role	role	NOUN
biomedich-1001	248	3	of	of	ADP
biomedich-1001	248	4	oxidative	oxidative	ADJ
biomedich-1001	248	5	stress	stress	NOUN
biomedich-1001	248	6	in	in	ADP
biomedich-1001	248	7	hyperuricemia	hyperuricemia	NOUN
biomedich-1001	248	8	and	and	CCONJ
biomedich-1001	248	9	xanthine	xanthine	NOUN
biomedich-1001	248	10	oxidoreductase	oxidoreductase	NOUN
biomedich-1001	248	11	(	(	PUNCT
biomedich-1001	248	12	xor	xor	PROPN
biomedich-1001	248	13	)	)	PUNCT
biomedich-1001	248	14	inhibitors	inhibitor	NOUN
biomedich-1001	248	15	.	.	PUNCT
biomedich-1001	249	1	oxidative	oxidative	ADJ
biomedich-1001	249	2	medicine	medicine	NOUN
biomedich-1001	249	3	and	and	CCONJ
biomedich-1001	249	4	cellular	cellular	ADJ
biomedich-1001	249	5	longevity	longevity	NOUN
biomedich-1001	249	6	,	,	PUNCT
biomedich-1001	249	7	2021(1	2021(1	NUM
biomedich-1001	249	8	)	)	PUNCT
biomedich-1001	249	9	,	,	PUNCT
biomedich-1001	249	10	1470380	1470380	NUM
biomedich-1001	249	11	.	.	PUNCT
biomedich-1001	250	1	https://doi.org/10.1155/2021/1470380	https://doi.org/10.1155/2021/1470380	NOUN
biomedich-1001	250	2	mardianingrum	mardianingrum	PROPN
biomedich-1001	250	3	,	,	PUNCT
biomedich-1001	250	4	r.	r.	PROPN
biomedich-1001	250	5	,	,	PUNCT
biomedich-1001	250	6	bachtiar	bachtiar	PROPN
biomedich-1001	250	7	,	,	PUNCT
biomedich-1001	250	8	k.	k.	PROPN
biomedich-1001	250	9	r.	r.	PROPN
biomedich-1001	250	10	,	,	PUNCT
biomedich-1001	250	11	susanti	susanti	PROPN
biomedich-1001	250	12	,	,	PUNCT
biomedich-1001	250	13	s.	s.	PROPN
biomedich-1001	250	14	,	,	PUNCT
biomedich-1001	250	15	aas	aas	PROPN
biomedich-1001	250	16	nuraisah	nuraisah	PROPN
biomedich-1001	250	17	,	,	PUNCT
biomedich-1001	250	18	a.	a.	NOUN
biomedich-1001	250	19	n.	n.	PROPN
biomedich-1001	250	20	,	,	PUNCT
biomedich-1001	250	21	&	&	CCONJ
biomedich-1001	250	22	ruswanto	ruswanto	PROPN
biomedich-1001	250	23	,	,	PUNCT
biomedich-1001	250	24	r.	r.	PROPN
biomedich-1001	250	25	(	(	PUNCT
biomedich-1001	250	26	2021	2021	NUM
biomedich-1001	250	27	)	)	PUNCT
biomedich-1001	250	28	.	.	PUNCT
biomedich-1001	251	1	studi	studi	PROPN
biomedich-1001	251	2	in	in	ADP
biomedich-1001	251	3	silico	silico	NOUN
biomedich-1001	251	4	senyawa	senyawa	NOUN
biomedich-1001	251	5	1,4naphthalenedione-2	1,4naphthalenedione-2	NUM
biomedich-1001	251	6	-	-	PUNCT
biomedich-1001	251	7	ethyl-3	ethyl-3	NUM
biomedich-1001	251	8	-	-	PUNCT
biomedich-1001	251	9	hydroxy	hydroxy	PROPN
biomedich-1001	251	10	sebagai	sebagai	PROPN
biomedich-1001	251	11	antiinflamasi	antiinflamasi	PROPN
biomedich-1001	251	12	dan	dan	PROPN
biomedich-1001	251	13	antikanker	antikanker	PROPN
biomedich-1001	251	14	payudara	payudara	NOUN
biomedich-1001	251	15	.	.	PUNCT
biomedich-1001	252	1	alchemy	alchemy	VERB
biomedich-1001	252	2	jurnal	jurnal	ADJ
biomedich-1001	252	3	penelitian	penelitian	PROPN
biomedich-1001	252	4	kimia	kimia	NOUN
biomedich-1001	252	5	,	,	PUNCT
biomedich-1001	252	6	17(1	17(1	NUM
biomedich-1001	252	7	)	)	PUNCT
biomedich-1001	252	8	,	,	PUNCT
biomedich-1001	252	9	83	83	NUM
biomedich-1001	252	10	.	.	PUNCT
biomedich-1001	253	1	https://doi.org/10.20961/alchemy.17.1.43979.83-95	https://doi.org/10.20961/alchemy.17.1.43979.83-95	NOUN
biomedich-1001	253	2	mehmood	mehmood	PROPN
biomedich-1001	253	3	,	,	PUNCT
biomedich-1001	253	4	a.	a.	PROPN
biomedich-1001	253	5	,	,	PUNCT
biomedich-1001	253	6	ishaq	ishaq	PROPN
biomedich-1001	253	7	,	,	PUNCT
biomedich-1001	253	8	m.	m.	NOUN
biomedich-1001	253	9	,	,	PUNCT
biomedich-1001	253	10	zhao	zhao	PROPN
biomedich-1001	253	11	,	,	PUNCT
biomedich-1001	253	12	l.	l.	PROPN
biomedich-1001	253	13	,	,	PUNCT
biomedich-1001	253	14	safdar	safdar	PROPN
biomedich-1001	253	15	,	,	PUNCT
biomedich-1001	253	16	b.	b.	PROPN
biomedich-1001	253	17	,	,	PUNCT
biomedich-1001	253	18	rehman	rehman	PROPN
biomedich-1001	253	19	,	,	PUNCT
biomedich-1001	253	20	a.	a.	PROPN
biomedich-1001	253	21	,	,	PUNCT
biomedich-1001	253	22	munir	munir	PROPN
biomedich-1001	253	23	,	,	PUNCT
biomedich-1001	253	24	m.	m.	NOUN
biomedich-1001	253	25	,	,	PUNCT
biomedich-1001	253	26	raza	raza	PROPN
biomedich-1001	253	27	,	,	PUNCT
biomedich-1001	253	28	a.	a.	NOUN
biomedich-1001	253	29	,	,	PUNCT
biomedich-1001	253	30	nadeem	nadeem	PROPN
biomedich-1001	253	31	,	,	PUNCT
biomedich-1001	253	32	m.	m.	NOUN
biomedich-1001	253	33	,	,	PUNCT
biomedich-1001	253	34	iqbal	iqbal	PROPN
biomedich-1001	253	35	,	,	PUNCT
biomedich-1001	253	36	w.	w.	PROPN
biomedich-1001	253	37	,	,	PUNCT
biomedich-1001	253	38	&	&	CCONJ
biomedich-1001	253	39	wang	wang	PROPN
biomedich-1001	253	40	,	,	PUNCT
biomedich-1001	253	41	c.	c.	PROPN
biomedich-1001	253	42	(	(	PUNCT
biomedich-1001	253	43	2019	2019	NUM
biomedich-1001	253	44	)	)	PUNCT
biomedich-1001	253	45	.	.	PUNCT
biomedich-1001	254	1	natural	natural	ADJ
biomedich-1001	254	2	compounds	compound	NOUN
biomedich-1001	254	3	with	with	ADP
biomedich-1001	254	4	xanthine	xanthine	NOUN
biomedich-1001	254	5	oxidase	oxidase	NOUN
biomedich-1001	254	6	inhibitory	inhibitory	ADJ
biomedich-1001	254	7	activity	activity	NOUN
biomedich-1001	254	8	:	:	PUNCT
biomedich-1001	254	9	a	a	DET
biomedich-1001	254	10	review	review	NOUN
biomedich-1001	254	11	.	.	PUNCT
biomedich-1001	255	1	chemical	chemical	NOUN
biomedich-1001	255	2	biology	biology	PROPN
biomedich-1001	255	3	&	&	CCONJ
biomedich-1001	255	4	drug	drug	PROPN
biomedich-1001	255	5	design	design	NOUN
biomedich-1001	255	6	,	,	PUNCT
biomedich-1001	255	7	93(4	93(4	NOUN
biomedich-1001	255	8	)	)	PUNCT
biomedich-1001	255	9	,	,	PUNCT
biomedich-1001	255	10	387–418	387–418	NUM
biomedich-1001	255	11	.	.	PUNCT
biomedich-1001	256	1	https://doi.org/10.1111/cbdd.13437	https://doi.org/10.1111/cbdd.13437	NOUN
biomedich-1001	256	2	mekky	mekky	ADJ
biomedich-1001	256	3	,	,	PUNCT
biomedich-1001	256	4	r.	r.	PROPN
biomedich-1001	256	5	h.	h.	PROPN
biomedich-1001	256	6	,	,	PUNCT
biomedich-1001	256	7	hegazy	hegazy	ADV
biomedich-1001	256	8	,	,	PUNCT
biomedich-1001	256	9	m.	m.	NOUN
biomedich-1001	256	10	m.	m.	NOUN
biomedich-1001	256	11	,	,	PUNCT
biomedich-1001	256	12	afifi	afifi	PROPN
biomedich-1001	256	13	,	,	PUNCT
biomedich-1001	256	14	w.	w.	PROPN
biomedich-1001	256	15	m.	m.	PROPN
biomedich-1001	256	16	,	,	PUNCT
biomedich-1001	256	17	mostafa	mostafa	PROPN
biomedich-1001	256	18	,	,	PUNCT
biomedich-1001	256	19	a.	a.	PROPN
biomedich-1001	256	20	e.	e.	PROPN
biomedich-1001	256	21	,	,	PUNCT
biomedich-1001	256	22	abbass	abbass	PROPN
biomedich-1001	256	23	,	,	PUNCT
biomedich-1001	256	24	h.	h.	PROPN
biomedich-1001	256	25	s.	s.	PROPN
biomedich-1001	256	26	,	,	PUNCT
biomedich-1001	256	27	&	&	CCONJ
biomedich-1001	256	28	abd	abd	PROPN
biomedich-1001	256	29	-	-	PUNCT
biomedich-1001	256	30	elraouf	elraouf	PROPN
biomedich-1001	256	31	,	,	PUNCT
biomedich-1001	256	32	m.	m.	NOUN
biomedich-1001	256	33	(	(	PUNCT
biomedich-1001	256	34	2023	2023	NUM
biomedich-1001	256	35	)	)	PUNCT
biomedich-1001	256	36	.	.	PUNCT
biomedich-1001	257	1	composition	composition	NOUN
biomedich-1001	257	2	and	and	CCONJ
biomedich-1001	257	3	functional	functional	ADJ
biomedich-1001	257	4	properties	property	NOUN
biomedich-1001	257	5	of	of	ADP
biomedich-1001	257	6	cardamom	cardamom	NOUN
biomedich-1001	257	7	leaves	leave	NOUN
biomedich-1001	257	8	.	.	PUNCT
biomedich-1001	258	1	in	in	ADP
biomedich-1001	258	2	m.	m.	PROPN
biomedich-1001	258	3	f.	f.	PROPN
biomedich-1001	258	4	ramadan	ramadan	PROPN
biomedich-1001	258	5	(	(	PUNCT
biomedich-1001	258	6	ed	ed	NOUN
biomedich-1001	258	7	.	.	PUNCT
biomedich-1001	258	8	)	)	PUNCT
biomedich-1001	258	9	,	,	PUNCT
biomedich-1001	258	10	cardamom	cardamom	NOUN
biomedich-1001	258	11	(	(	PUNCT
biomedich-1001	258	12	elettaria	elettaria	NOUN
biomedich-1001	258	13	cardamomum	cardamomum	ADJ
biomedich-1001	258	14	):	):	PUNCT
biomedich-1001	258	15	production	production	NOUN
biomedich-1001	258	16	,	,	PUNCT
biomedich-1001	258	17	processing	processing	NOUN
biomedich-1001	258	18	and	and	CCONJ
biomedich-1001	258	19	properties	property	NOUN
biomedich-1001	258	20	(	(	PUNCT
biomedich-1001	258	21	pp	pp	ADJ
biomedich-1001	258	22	.	.	PUNCT
biomedich-1001	259	1	157–178	157–178	NUM
biomedich-1001	259	2	)	)	PUNCT
biomedich-1001	259	3	.	.	PUNCT
biomedich-1001	260	1	springer	springer	NOUN
biomedich-1001	260	2	international	international	ADJ
biomedich-1001	260	3	publishing	publishing	NOUN
biomedich-1001	260	4	.	.	PUNCT
biomedich-1001	261	1	https://doi.org/10.1007/978-3-03135426-7_12	https://doi.org/10.1007/978-3-03135426-7_12	X
biomedich-1001	261	2	monikasari	monikasari	PROPN
biomedich-1001	261	3	,	,	PUNCT
biomedich-1001	261	4	h.	h.	PROPN
biomedich-1001	261	5	,	,	PUNCT
biomedich-1001	261	6	mardianingrum	mardianingrum	PROPN
biomedich-1001	261	7	,	,	PUNCT
biomedich-1001	261	8	r.	r.	PROPN
biomedich-1001	261	9	,	,	PUNCT
biomedich-1001	261	10	&	&	CCONJ
biomedich-1001	261	11	bachtiar	bachtiar	PROPN
biomedich-1001	261	12	,	,	PUNCT
biomedich-1001	261	13	k.	k.	PROPN
biomedich-1001	261	14	r.	r.	PROPN
biomedich-1001	261	15	(	(	PUNCT
biomedich-1001	261	16	2023	2023	NUM
biomedich-1001	261	17	)	)	PUNCT
biomedich-1001	261	18	.	.	PUNCT
biomedich-1001	262	1	kajian	kajian	PROPN
biomedich-1001	262	2	dari	dari	PROPN
biomedich-1001	262	3	senyawa	senyawa	PROPN
biomedich-1001	262	4	umbi	umbi	PROPN
biomedich-1001	262	5	bawang	bawang	PROPN
biomedich-1001	262	6	putih	putih	PROPN
biomedich-1001	262	7	(	(	PUNCT
biomedich-1001	262	8	allium	allium	NOUN
biomedich-1001	262	9	sativum	sativum	PROPN
biomedich-1001	262	10	l.	l.	PROPN
biomedich-1001	262	11	)	)	PUNCT
biomedich-1001	262	12	terhadap	terhadap	PROPN
biomedich-1001	262	13	interaksi	interaksi	PROPN
biomedich-1001	262	14	aktif	aktif	PROPN
biomedich-1001	262	15	sebagai	sebagai	PROPN
biomedich-1001	262	16	analgetik	analgetik	PROPN
biomedich-1001	262	17	-	-	PUNCT
biomedich-1001	262	18	antiinflamasi	antiinflamasi	PROPN
biomedich-1001	262	19	secara	secara	PROPN
biomedich-1001	262	20	in	in	ADP
biomedich-1001	262	21	silico	silico	NOUN
biomedich-1001	262	22	.	.	PUNCT
biomedich-1001	263	1	jurnal	jurnal	PROPN
biomedich-1001	263	2	farmasi	farmasi	PROPN
biomedich-1001	263	3	sandi	sandi	PROPN
biomedich-1001	263	4	karsa	karsa	PROPN
biomedich-1001	263	5	,	,	PUNCT
biomedich-1001	263	6	9(2	9(2	NUM
biomedich-1001	263	7	)	)	PUNCT
biomedich-1001	263	8	,	,	PUNCT
biomedich-1001	263	9	60–73	60–73	PROPN
biomedich-1001	263	10	.	.	PUNCT
biomedich-1001	264	1	https://doi.org/10.36060/jfs.v9i2.96	https://doi.org/10.36060/jfs.v9i2.96	PROPN
biomedich-1001	264	2	muttaqin	muttaqin	PROPN
biomedich-1001	264	3	,	,	PUNCT
biomedich-1001	264	4	f.	f.	PROPN
biomedich-1001	264	5	z.	z.	PROPN
biomedich-1001	264	6	(	(	PUNCT
biomedich-1001	264	7	2019	2019	NUM
biomedich-1001	264	8	)	)	PUNCT
biomedich-1001	264	9	.	.	PUNCT
biomedich-1001	265	1	studi	studi	PROPN
biomedich-1001	265	2	molecular	molecular	ADJ
biomedich-1001	265	3	docking	docking	NOUN
biomedich-1001	265	4	,	,	PUNCT
biomedich-1001	265	5	molecular	molecular	ADJ
biomedich-1001	265	6	dynamic	dynamic	ADJ
biomedich-1001	265	7	,	,	PUNCT
biomedich-1001	265	8	dan	dan	PROPN
biomedich-1001	265	9	prediksi	prediksi	PROPN
biomedich-1001	265	10	toksisitas	toksisitas	PROPN
biomedich-1001	265	11	senyawa	senyawa	PROPN
biomedich-1001	266	1	turunan	turunan	PROPN
biomedich-1001	266	2	alkaloid	alkaloid	PROPN
biomedich-1001	266	3	naftiridin	naftiridin	PROPN
biomedich-1001	266	4	sebagai	sebagai	PROPN
biomedich-1001	266	5	inhibitor	inhibitor	NOUN
biomedich-1001	266	6	protein	protein	NOUN
biomedich-1001	266	7	kasein	kasein	PROPN
biomedich-1001	266	8	kinase	kinase	PROPN
biomedich-1001	266	9	2	2	NUM
biomedich-1001	266	10	-	-	PUNCT
biomedich-1001	266	11	α	α	PROPN
biomedich-1001	266	12	pada	pada	NOUN
biomedich-1001	266	13	kanker	kanker	NOUN
biomedich-1001	266	14	leukemia	leukemia	PROPN
biomedich-1001	266	15	.	.	PUNCT
biomedich-1001	267	1	pharmacoscript	pharmacoscript	NOUN
biomedich-1001	267	2	,	,	PUNCT
biomedich-1001	267	3	2(1	2(1	NUM
biomedich-1001	267	4	)	)	PUNCT
biomedich-1001	267	5	,	,	PUNCT
biomedich-1001	267	6	49–64	49–64	PROPN
biomedich-1001	267	7	.	.	PUNCT
biomedich-1001	268	1	https://doi.org/10.36423/pharmacoscript.v2i1.241	https://doi.org/10.36423/pharmacoscript.v2i1.241	X
biomedich-1001	268	2	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	268	3	,	,	PUNCT
biomedich-1001	268	4	a.	a.	NOUN
biomedich-1001	268	5	,	,	PUNCT
biomedich-1001	268	6	rahmawati	rahmawati	NOUN
biomedich-1001	268	7	,	,	PUNCT
biomedich-1001	268	8	n.	n.	PROPN
biomedich-1001	268	9	a.	a.	PROPN
biomedich-1001	268	10	,	,	PUNCT
biomedich-1001	268	11	nurzaman	nurzaman	PROPN
biomedich-1001	268	12	,	,	PUNCT
biomedich-1001	268	13	m.	m.	PROPN
biomedich-1001	268	14	h.	h.	PROPN
biomedich-1001	268	15	,	,	PUNCT
biomedich-1001	268	16	fadilah	fadilah	PROPN
biomedich-1001	268	17	,	,	PUNCT
biomedich-1001	268	18	n.	n.	PROPN
biomedich-1001	268	19	n.	n.	PROPN
biomedich-1001	268	20	,	,	PUNCT
biomedich-1001	268	21	&	&	CCONJ
biomedich-1001	268	22	isnaeni	isnaeni	PROPN
biomedich-1001	268	23	,	,	PUNCT
biomedich-1001	268	24	s.	s.	PROPN
biomedich-1001	268	25	(	(	PUNCT
biomedich-1001	268	26	2025	2025	NUM
biomedich-1001	268	27	)	)	PUNCT
biomedich-1001	268	28	.	.	PUNCT
biomedich-1001	269	1	in	in	ADP
biomedich-1001	269	2	silico	silico	NOUN
biomedich-1001	269	3	study	study	NOUN
biomedich-1001	269	4	of	of	ADP
biomedich-1001	269	5	java	java	PROPN
biomedich-1001	269	6	cardamom	cardamom	PROPN
biomedich-1001	269	7	(	(	PUNCT
biomedich-1001	269	8	amomum	amomum	ADJ
biomedich-1001	269	9	compactum	compactum	NOUN
biomedich-1001	269	10	)	)	PUNCT
biomedich-1001	269	11	fruit	fruit	NOUN
biomedich-1001	269	12	derivative	derivative	ADJ
biomedich-1001	269	13	compounds	compound	NOUN
biomedich-1001	269	14	as	as	ADP
biomedich-1001	269	15	antihyperuricemia	antihyperuricemia	NOUN
biomedich-1001	269	16	.	.	PUNCT
biomedich-1001	270	1	tropical	tropical	ADJ
biomedich-1001	270	2	journal	journal	PROPN
biomedich-1001	270	3	of	of	ADP
biomedich-1001	270	4	natural	natural	ADJ
biomedich-1001	270	5	product	product	NOUN
biomedich-1001	270	6	research	research	NOUN
biomedich-1001	270	7	,	,	PUNCT
biomedich-1001	270	8	7(9	7(9	NUM
biomedich-1001	270	9	)	)	PUNCT
biomedich-1001	270	10	.	.	PUNCT
biomedich-1001	271	1	https://doi.org/10.26538/tjnpr/v9i7.10	https://doi.org/10.26538/tjnpr/v9i7.10	PROPN
biomedich-1001	271	2	nurhikma	nurhikma	PROPN
biomedich-1001	271	3	,	,	PUNCT
biomedich-1001	271	4	e.	e.	PROPN
biomedich-1001	271	5	,	,	PUNCT
biomedich-1001	271	6	jannah	jannah	PROPN
biomedich-1001	271	7	,	,	PUNCT
biomedich-1001	271	8	s.	s.	PROPN
biomedich-1001	271	9	r.	r.	PROPN
biomedich-1001	271	10	n.	n.	PROPN
biomedich-1001	271	11	,	,	PUNCT
biomedich-1001	271	12	wijaya	wijaya	PROPN
biomedich-1001	271	13	,	,	PUNCT
biomedich-1001	271	14	d.	d.	PROPN
biomedich-1001	271	15	p.	p.	PROPN
biomedich-1001	271	16	,	,	PUNCT
biomedich-1001	271	17	zulham	zulham	PROPN
biomedich-1001	271	18	,	,	PUNCT
biomedich-1001	271	19	z.	z.	PROPN
biomedich-1001	271	20	,	,	PUNCT
biomedich-1001	271	21	astari	astari	PROPN
biomedich-1001	271	22	,	,	PUNCT
biomedich-1001	271	23	c.	c.	NOUN
biomedich-1001	271	24	,	,	PUNCT
biomedich-1001	271	25	nofriyaldi	nofriyaldi	PROPN
biomedich-1001	271	26	,	,	PUNCT
biomedich-1001	271	27	a.	a.	NOUN
biomedich-1001	271	28	,	,	PUNCT
biomedich-1001	271	29	purnamasari	purnamasari	PROPN
biomedich-1001	271	30	,	,	PUNCT
biomedich-1001	271	31	n.	n.	PROPN
biomedich-1001	271	32	,	,	PUNCT
biomedich-1001	271	33	&	&	CCONJ
biomedich-1001	271	34	indalifiany	indalifiany	PROPN
biomedich-1001	271	35	,	,	PUNCT
biomedich-1001	271	36	a.	a.	NOUN
biomedich-1001	271	37	(	(	PUNCT
biomedich-1001	271	38	2024	2024	NUM
biomedich-1001	271	39	)	)	PUNCT
biomedich-1001	271	40	.	.	PUNCT
biomedich-1001	272	1	farmasetika	farmasetika	X
biomedich-1001	272	2	(	(	PUNCT
biomedich-1001	272	3	1st	1st	ADJ
biomedich-1001	272	4	ed	ed	NOUN
biomedich-1001	272	5	.	.	PUNCT
biomedich-1001	272	6	)	)	PUNCT
biomedich-1001	272	7	.	.	PUNCT
biomedich-1001	273	1	widina	widina	PROPN
biomedich-1001	273	2	media	media	PROPN
biomedich-1001	273	3	utama	utama	PROPN
biomedich-1001	273	4	.	.	PUNCT
biomedich-1001	274	1	pasaribu	pasaribu	PROPN
biomedich-1001	274	2	,	,	PUNCT
biomedich-1001	274	3	e.	e.	PROPN
biomedich-1001	274	4	(	(	PUNCT
biomedich-1001	274	5	2024	2024	NUM
biomedich-1001	274	6	)	)	PUNCT
biomedich-1001	274	7	.	.	PUNCT
biomedich-1001	275	1	biofarmasetika	biofarmasetika	PROPN
biomedich-1001	275	2	obat	obat	PROPN
biomedich-1001	275	3	sediaan	sediaan	PROPN
biomedich-1001	275	4	oral	oral	PROPN
biomedich-1001	275	5	.	.	PUNCT
biomedich-1001	276	1	in	in	ADP
biomedich-1001	276	2	biofarmasetika	biofarmasetika	NOUN
biomedich-1001	276	3	.	.	PUNCT
biomedich-1001	277	1	media	medium	NOUN
biomedich-1001	277	2	sains	sains	PROPN
biomedich-1001	277	3	indonesia	indonesia	PROPN
biomedich-1001	277	4	.	.	PUNCT
biomedich-1001	277	5	rahmawaty	rahmawaty	PROPN
biomedich-1001	277	6	,	,	PUNCT
biomedich-1001	277	7	a.	a.	NOUN
biomedich-1001	277	8	,	,	PUNCT
biomedich-1001	277	9	cahyani	cahyani	PROPN
biomedich-1001	277	10	,	,	PUNCT
biomedich-1001	277	11	f.	f.	PROPN
biomedich-1001	277	12	r.	r.	PROPN
biomedich-1001	277	13	,	,	PUNCT
biomedich-1001	277	14	safitri	safitri	ADJ
biomedich-1001	277	15	,	,	PUNCT
biomedich-1001	277	16	n.	n.	NOUN
biomedich-1001	277	17	,	,	PUNCT
biomedich-1001	277	18	hapitria	hapitria	PROPN
biomedich-1001	277	19	,	,	PUNCT
biomedich-1001	277	20	e.	e.	PROPN
biomedich-1001	277	21	n.	n.	PROPN
biomedich-1001	277	22	,	,	PUNCT
biomedich-1001	277	23	&	&	CCONJ
biomedich-1001	277	24	megantara	megantara	PROPN
biomedich-1001	277	25	,	,	PUNCT
biomedich-1001	277	26	s.	s.	PROPN
biomedich-1001	277	27	(	(	PUNCT
biomedich-1001	277	28	2022	2022	NUM
biomedich-1001	277	29	)	)	PUNCT
biomedich-1001	277	30	.	.	PUNCT
biomedich-1001	278	1	uji	uji	PROPN
biomedich-1001	278	2	in	in	ADP
biomedich-1001	278	3	silico	silico	NOUN
biomedich-1001	279	1	kandungan	kandungan	NOUN
biomedich-1001	279	2	senyawa	senyawa	PROPN
biomedich-1001	279	3	tanaman	tanaman	PROPN
biomedich-1001	279	4	anggur	anggur	PROPN
biomedich-1001	279	5	(	(	PUNCT
biomedich-1001	279	6	vitis	vitis	PROPN
biomedich-1001	279	7	vinifera	vinifera	NOUN
biomedich-1001	279	8	l.	l.	PROPN
biomedich-1001	279	9	)	)	PUNCT
biomedich-1001	279	10	untuk	untuk	PROPN
biomedich-1001	279	11	kandidat	kandidat	PROPN
biomedich-1001	279	12	obat	obat	PROPN
biomedich-1001	279	13	anti	anti	PROPN
biomedich-1001	279	14	hiperlipidemia	hiperlipidemia	PROPN
biomedich-1001	279	15	.	.	PUNCT
biomedich-1001	280	1	majalah	majalah	PROPN
biomedich-1001	280	2	farmasi	farmasi	PROPN
biomedich-1001	280	3	dan	dan	PROPN
biomedich-1001	280	4	farmakologi	farmakologi	PROPN
biomedich-1001	280	5	.	.	PUNCT
biomedich-1001	281	1	https://doi.org/10.20956/mff.v26i2.19859	https://doi.org/10.20956/mff.v26i2.19859	PROPN
biomedich-1001	281	2	ruswanto	ruswanto	NOUN
biomedich-1001	281	3	,	,	PUNCT
biomedich-1001	281	4	r.	r.	PROPN
biomedich-1001	281	5	,	,	PUNCT
biomedich-1001	281	6	mardianingrum	mardianingrum	PROPN
biomedich-1001	281	7	,	,	PUNCT
biomedich-1001	281	8	r.	r.	PROPN
biomedich-1001	281	9	,	,	PUNCT
biomedich-1001	281	10	nofianti	nofianti	NOUN
biomedich-1001	281	11	,	,	PUNCT
biomedich-1001	281	12	t.	t.	PROPN
biomedich-1001	281	13	,	,	PUNCT
biomedich-1001	281	14	pratita	pratita	PROPN
biomedich-1001	281	15	,	,	PUNCT
biomedich-1001	281	16	a.	a.	NOUN
biomedich-1001	281	17	t.	t.	PROPN
biomedich-1001	281	18	k.	k.	PROPN
biomedich-1001	281	19	,	,	PUNCT
biomedich-1001	281	20	naser	naser	PROPN
biomedich-1001	281	21	,	,	PUNCT
biomedich-1001	281	22	f.	f.	PROPN
biomedich-1001	281	23	m.	m.	PROPN
biomedich-1001	281	24	,	,	PUNCT
biomedich-1001	281	25	&	&	CCONJ
biomedich-1001	281	26	siswandono	siswandono	PROPN
biomedich-1001	281	27	,	,	PUNCT
biomedich-1001	281	28	s.	s.	PROPN
biomedich-1001	281	29	(	(	PUNCT
biomedich-1001	281	30	2023	2023	NUM
biomedich-1001	281	31	)	)	PUNCT
biomedich-1001	281	32	.	.	PUNCT
biomedich-1001	282	1	design	design	NOUN
biomedich-1001	282	2	and	and	CCONJ
biomedich-1001	282	3	computational	computational	ADJ
biomedich-1001	282	4	study	study	NOUN
biomedich-1001	282	5	of	of	ADP
biomedich-1001	282	6	the	the	DET
biomedich-1001	282	7	thiourea	thiourea	NOUN
biomedich-1001	282	8	–	–	PUNCT
biomedich-1001	282	9	cobalt(iii	cobalt(iii	NOUN
biomedich-1001	282	10	)	)	PUNCT
biomedich-1001	282	11	complex	complex	NOUN
biomedich-1001	282	12	as	as	ADP
biomedich-1001	282	13	an	an	DET
biomedich-1001	282	14	anticancer	anticancer	NOUN
biomedich-1001	282	15	candidate	candidate	NOUN
biomedich-1001	282	16	.	.	PUNCT
biomedich-1001	282	17	journal	journal	PROPN
biomedich-1001	282	18	of	of	ADP
biomedich-1001	282	19	pharmacy	pharmacy	PROPN
biomedich-1001	282	20	&	&	CCONJ
biomedich-1001	282	21	pharmacognosy	pharmacognosy	PROPN
biomedich-1001	282	22	research	research	NOUN
biomedich-1001	282	23	,	,	PUNCT
biomedich-1001	282	24	11(3	11(3	NUM
biomedich-1001	282	25	)	)	PUNCT
biomedich-1001	282	26	,	,	PUNCT
biomedich-1001	282	27	499–516	499–516	NUM
biomedich-1001	282	28	.	.	PUNCT
biomedich-1001	283	1	https://doi.org/10.56499/jppres23.1622_11.3.499	https://doi.org/10.56499/jppres23.1622_11.3.499	PROPN
biomedich-1001	283	2	ruswanto	ruswanto	NOUN
biomedich-1001	283	3	,	,	PUNCT
biomedich-1001	283	4	t.	t.	PROPN
biomedich-1001	283	5	,	,	PUNCT
biomedich-1001	283	6	nofianti	nofianti	NOUN
biomedich-1001	283	7	,	,	PUNCT
biomedich-1001	283	8	t.	t.	PROPN
biomedich-1001	283	9	,	,	PUNCT
biomedich-1001	283	10	mardianingrum	mardianingrum	PROPN
biomedich-1001	283	11	,	,	PUNCT
biomedich-1001	283	12	r.	r.	PROPN
biomedich-1001	283	13	,	,	PUNCT
biomedich-1001	283	14	lestari	lestari	PROPN
biomedich-1001	283	15	,	,	PUNCT
biomedich-1001	283	16	a.	a.	NOUN
biomedich-1001	283	17	,	,	PUNCT
biomedich-1001	283	18	&	&	CCONJ
biomedich-1001	283	19	sepriliani	sepriliani	PROPN
biomedich-1001	283	20	,	,	PUNCT
biomedich-1001	283	21	t.	t.	PROPN
biomedich-1001	283	22	(	(	PUNCT
biomedich-1001	283	23	2018	2018	NUM
biomedich-1001	283	24	)	)	PUNCT
biomedich-1001	283	25	.	.	PUNCT
biomedich-1001	284	1	desain	desain	PROPN
biomedich-1001	284	2	dan	dan	PROPN
biomedich-1001	284	3	studi	studi	PROPN
biomedich-1001	284	4	in	in	ADP
biomedich-1001	284	5	silico	silico	NOUN
biomedich-1001	284	6	senyawa	senyawa	NOUN
biomedich-1001	284	7	turunan	turunan	PROPN
biomedich-1001	284	8	kuwanon	kuwanon	PROPN
biomedich-1001	284	9	-	-	PROPN
biomedich-1001	284	10	h	h	PROPN
biomedich-1001	284	11	sebagai	sebagai	PROPN
biomedich-1001	284	12	kandidat	kandidat	PROPN
biomedich-1001	284	13	obat	obat	PROPN
biomedich-1001	284	14	anti	anti	PROPN
biomedich-1001	284	15	hiv	hiv	PROPN
biomedich-1001	284	16	design	design	NOUN
biomedich-1001	284	17	and	and	CCONJ
biomedich-1001	284	18	in	in	ADP
biomedich-1001	284	19	silico	silico	NOUN
biomedich-1001	284	20	study	study	NOUN
biomedich-1001	284	21	of	of	ADP
biomedich-1001	284	22	kuwanon	kuwanon	PROPN
biomedich-1001	284	23	-	-	PUNCT
biomedich-1001	284	24	h	h	PROPN
biomedich-1001	284	25	as	as	ADP
biomedich-1001	284	26	anti	anti	ADJ
biomedich-1001	284	27	hiv	hiv	PROPN
biomedich-1001	284	28	drug	drug	NOUN
biomedich-1001	284	29	candidate	candidate	NOUN
biomedich-1001	284	30	.	.	PUNCT
biomedich-1001	285	1	jurnal	jurnal	PROPN
biomedich-1001	285	2	kimia	kimia	PROPN
biomedich-1001	285	3	valensi	valensi	PROPN
biomedich-1001	285	4	,	,	PUNCT
biomedich-1001	285	5	4(1	4(1	PROPN
biomedich-1001	285	6	)	)	PUNCT
biomedich-1001	285	7	.	.	PUNCT
biomedich-1001	286	1	sagitasa	sagitasa	PROPN
biomedich-1001	286	2	,	,	PUNCT
biomedich-1001	286	3	s.	s.	PROPN
biomedich-1001	286	4	,	,	PUNCT
biomedich-1001	286	5	elizabeth	elizabeth	PROPN
biomedich-1001	286	6	,	,	PUNCT
biomedich-1001	286	7	k.	k.	PROPN
biomedich-1001	286	8	,	,	PUNCT
biomedich-1001	286	9	sulaeman	sulaeman	PROPN
biomedich-1001	286	10	,	,	PUNCT
biomedich-1001	286	11	l.	l.	PROPN
biomedich-1001	286	12	i.	i.	PROPN
biomedich-1001	286	13	,	,	PUNCT
biomedich-1001	286	14	rafasafly	rafasafly	VERB
biomedich-1001	286	15	,	,	PUNCT
biomedich-1001	286	16	a.	a.	NOUN
biomedich-1001	286	17	,	,	PUNCT
biomedich-1001	286	18	syafra	syafra	NOUN
biomedich-1001	286	19	,	,	PUNCT
biomedich-1001	286	20	d.	d.	PROPN
biomedich-1001	286	21	w.	w.	PROPN
biomedich-1001	286	22	,	,	PUNCT
biomedich-1001	286	23	kristande	kristande	PROPN
biomedich-1001	286	24	,	,	PUNCT
biomedich-1001	286	25	a.	a.	NOUN
biomedich-1001	286	26	,	,	PUNCT
biomedich-1001	286	27	&	&	CCONJ
biomedich-1001	286	28	muchtaridi	muchtaridi	NOUN
biomedich-1001	286	29	,	,	PUNCT
biomedich-1001	286	30	m.	m.	NOUN
biomedich-1001	286	31	(	(	PUNCT
biomedich-1001	286	32	2021	2021	NUM
biomedich-1001	286	33	)	)	PUNCT
biomedich-1001	286	34	.	.	PUNCT
biomedich-1001	287	1	studi	studi	PROPN
biomedich-1001	287	2	in	in	ADP
biomedich-1001	287	3	silico	silico	NOUN
biomedich-1001	287	4	senyawa	senyawa	PROPN
biomedich-1001	287	5	aktif	aktif	PROPN
biomedich-1001	287	6	daun	daun	PROPN
biomedich-1001	287	7	singawalang	singawalang	PROPN
biomedich-1001	287	8	(	(	PUNCT
biomedich-1001	287	9	petiveria	petiveria	PROPN
biomedich-1001	287	10	alliacea	alliacea	PROPN
biomedich-1001	287	11	)	)	PUNCT
biomedich-1001	288	1	sebagai	sebagai	PROPN
biomedich-1001	288	2	penurun	penurun	PROPN
biomedich-1001	288	3	kadar	kadar	PROPN
biomedich-1001	288	4	glukosa	glukosa	PROPN
biomedich-1001	288	5	darah	darah	PROPN
biomedich-1001	288	6	untuk	untuk	PROPN
biomedich-1001	288	7	pengobatan	pengobatan	PROPN
biomedich-1001	288	8	penyakit	penyakit	PROPN
biomedich-1001	288	9	diabetes	diabetes	PROPN
biomedich-1001	288	10	melitus	melitus	PROPN
biomedich-1001	288	11	tipe-2	tipe-2	PROPN
biomedich-1001	288	12	.	.	PUNCT
biomedich-1001	289	1	chimica	chimica	PROPN
biomedich-1001	289	2	et	et	PROPN
biomedich-1001	289	3	natura	natura	PROPN
biomedich-1001	289	4	acta	acta	PROPN
biomedich-1001	289	5	,	,	PUNCT
biomedich-1001	289	6	9(2	9(2	NUM
biomedich-1001	289	7	)	)	PUNCT
biomedich-1001	289	8	.	.	PUNCT
biomedich-1001	290	1	https://doi.org/10.24198/cna.v9.n2.34083	https://doi.org/10.24198/cna.v9.n2.34083	PROPN
biomedich-1001	290	2	sari	sari	PROPN
biomedich-1001	290	3	,	,	PUNCT
biomedich-1001	290	4	i.	i.	PROPN
biomedich-1001	290	5	w.	w.	PROPN
biomedich-1001	290	6	,	,	PUNCT
biomedich-1001	290	7	junaidin	junaidin	VERB
biomedich-1001	290	8	,	,	PUNCT
biomedich-1001	290	9	j.	j.	PROPN
biomedich-1001	290	10	,	,	PUNCT
biomedich-1001	290	11	&	&	CCONJ
biomedich-1001	290	12	pratiwi	pratiwi	NOUN
biomedich-1001	290	13	,	,	PUNCT
biomedich-1001	290	14	d.	d.	PROPN
biomedich-1001	290	15	(	(	PUNCT
biomedich-1001	290	16	2020	2020	NUM
biomedich-1001	290	17	)	)	PUNCT
biomedich-1001	290	18	.	.	PUNCT
biomedich-1001	291	1	studi	studi	PROPN
biomedich-1001	291	2	molecular	molecular	ADJ
biomedich-1001	291	3	docking	docking	NOUN
biomedich-1001	291	4	senyawa	senyawa	NOUN
biomedich-1001	291	5	flavonoid	flavonoid	PROPN
biomedich-1001	291	6	herba	herba	PROPN
biomedich-1001	291	7	kumis	kumis	PROPN
biomedich-1001	291	8	kucing	kucing	PROPN
biomedich-1001	291	9	(	(	PUNCT
biomedich-1001	291	10	orthosiphon	orthosiphon	PROPN
biomedich-1001	291	11	stamineus	stamineus	PROPN
biomedich-1001	291	12	b.	b.	PROPN
biomedich-1001	291	13	)	)	PUNCT
biomedich-1001	291	14	pada	pada	PROPN
biomedich-1001	291	15	reseptor	reseptor	PROPN
biomedich-1001	291	16	α	α	PROPN
biomedich-1001	291	17	-	-	PUNCT
biomedich-1001	291	18	glukosidase	glukosidase	NOUN
biomedich-1001	291	19	sebagai	sebagai	PROPN
biomedich-1001	291	20	antidiabetes	antidiabete	VERB
biomedich-1001	291	21	tipe	tipe	PROPN
biomedich-1001	291	22	2	2	NUM
biomedich-1001	291	23	.	.	PUNCT
biomedich-1001	291	24	jurnal	jurnal	ADJ
biomedich-1001	291	25	farmagazine	farmagazine	NOUN
biomedich-1001	291	26	,	,	PUNCT
biomedich-1001	291	27	7(2	7(2	NUM
biomedich-1001	291	28	)	)	PUNCT
biomedich-1001	291	29	,	,	PUNCT
biomedich-1001	291	30	54	54	NUM
biomedich-1001	291	31	.	.	PUNCT
biomedich-1001	292	1	https://doi.org/10.47653/farm.v7i2.194	https://doi.org/10.47653/farm.v7i2.194	PROPN
biomedich-1001	292	2	sovia	sovia	PROPN
biomedich-1001	292	3	,	,	PUNCT
biomedich-1001	292	4	f.	f.	PROPN
biomedich-1001	292	5	,	,	PUNCT
biomedich-1001	292	6	a	a	DET
biomedich-1001	292	7	-	-	PUNCT
biomedich-1001	292	8	adawiyah	adawiyah	NOUN
biomedich-1001	292	9	,	,	PUNCT
biomedich-1001	292	10	r.	r.	PROPN
biomedich-1001	292	11	,	,	PUNCT
biomedich-1001	292	12	&	&	CCONJ
biomedich-1001	292	13	yuliana	yuliana	PROPN
biomedich-1001	292	14	,	,	PUNCT
biomedich-1001	292	15	t.	t.	PROPN
biomedich-1001	292	16	p.	p.	PROPN
biomedich-1001	292	17	(	(	PUNCT
biomedich-1001	292	18	2025	2025	NUM
biomedich-1001	292	19	)	)	PUNCT
biomedich-1001	292	20	.	.	PUNCT
biomedich-1001	293	1	evaluation	evaluation	NOUN
biomedich-1001	293	2	of	of	ADP
biomedich-1001	293	3	the	the	DET
biomedich-1001	293	4	effectiveness	effectiveness	NOUN
biomedich-1001	293	5	of	of	ADP
biomedich-1001	293	6	renggak	renggak	NOUN
biomedich-1001	293	7	leaf	leaf	NOUN
biomedich-1001	293	8	extract	extract	NOUN
biomedich-1001	293	9	(	(	PUNCT
biomedich-1001	293	10	amomum	amomum	ADJ
biomedich-1001	293	11	dealbatum	dealbatum	NOUN
biomedich-1001	293	12	roxb	roxb	NOUN
biomedich-1001	293	13	.	.	PUNCT
biomedich-1001	293	14	)	)	PUNCT
biomedich-1001	294	1	as	as	ADP
biomedich-1001	294	2	an	an	DET
biomedich-1001	294	3	antihyperuricemic	antihyperuricemic	ADJ
biomedich-1001	294	4	in	in	ADP
biomedich-1001	294	5	mice	mouse	NOUN
biomedich-1001	294	6	.	.	PUNCT
biomedich-1001	295	1	journal	journal	PROPN
biomedich-1001	295	2	of	of	ADP
biomedich-1001	295	3	pharmaceutical	pharmaceutical	NOUN
biomedich-1001	295	4	and	and	CCONJ
biomedich-1001	295	5	sciences	science	NOUN
biomedich-1001	295	6	,	,	PUNCT
biomedich-1001	295	7	8(2	8(2	NUM
biomedich-1001	295	8	)	)	PUNCT
biomedich-1001	295	9	,	,	PUNCT
biomedich-1001	295	10	1082–1090	1082–1090	NUM
biomedich-1001	295	11	.	.	PUNCT
biomedich-1001	296	1	https://doi.org/10.36490/journal-jps.com	https://doi.org/10.36490/journal-jps.com	PROPN
biomedich-1001	296	2	thahara	thahara	PROPN
biomedich-1001	296	3	,	,	PUNCT
biomedich-1001	296	4	c.	c.	PROPN
biomedich-1001	296	5	a.	a.	PROPN
biomedich-1001	296	6	,	,	PUNCT
biomedich-1001	296	7	rizarullah	rizarullah	VERB
biomedich-1001	296	8	*	*	PROPN
biomedich-1001	296	9	,	,	PUNCT
biomedich-1001	296	10	r.	r.	PROPN
biomedich-1001	296	11	,	,	PUNCT
biomedich-1001	296	12	atika	atika	PROPN
biomedich-1001	296	13	,	,	PUNCT
biomedich-1001	296	14	r.	r.	PROPN
biomedich-1001	296	15	a.	a.	PROPN
biomedich-1001	296	16	,	,	PUNCT
biomedich-1001	296	17	&	&	CCONJ
biomedich-1001	296	18	wahab	wahab	PROPN
biomedich-1001	296	19	,	,	PUNCT
biomedich-1001	296	20	a.	a.	NOUN
biomedich-1001	296	21	(	(	PUNCT
biomedich-1001	296	22	2022	2022	NUM
biomedich-1001	296	23	)	)	PUNCT
biomedich-1001	296	24	.	.	PUNCT
biomedich-1001	297	1	potensi	potensi	PROPN
biomedich-1001	297	2	pendekatan	pendekatan	PROPN
biomedich-1001	297	3	in	in	ADP
biomedich-1001	297	4	silico	silico	PROPN
biomedich-1001	297	5	sebagai	sebagai	PROPN
biomedich-1001	297	6	penghambat	penghambat	PROPN
biomedich-1001	297	7	aktivitas	aktivita	VERB
biomedich-1001	297	8	protein	protein	NOUN
biomedich-1001	297	9	protease	protease	NOUN
biomedich-1001	297	10	utama	utama	PROPN
biomedich-1001	297	11	sars	sar	NOUN
biomedich-1001	297	12	-	-	PUNCT
biomedich-1001	297	13	cov-2	cov-2	NOUN
biomedich-1001	297	14	dari	dari	ADJ
biomedich-1001	297	15	tiga	tiga	PROPN
biomedich-1001	297	16	senyawa	senyawa	PROPN
biomedich-1001	297	17	tanaman	tanaman	PROPN
biomedich-1001	297	18	obat	obat	PROPN
biomedich-1001	297	19	jahe	jahe	PROPN
biomedich-1001	297	20	merah	merah	PROPN
biomedich-1001	297	21	.	.	PUNCT
biomedich-1001	298	1	jurnal	jurnal	PROPN
biomedich-1001	298	2	ipa	ipa	PROPN
biomedich-1001	298	3	&	&	CCONJ
biomedich-1001	298	4	pembelajaran	pembelajaran	PROPN
biomedich-1001	298	5	ipa	ipa	PROPN
biomedich-1001	298	6	,	,	PUNCT
biomedich-1001	298	7	6(3	6(3	NUM
biomedich-1001	298	8	)	)	PUNCT
biomedich-1001	298	9	,	,	PUNCT
biomedich-1001	298	10	207–218	207–218	NUM
biomedich-1001	298	11	.	.	PUNCT
biomedich-1001	299	1	https://doi.org/10.24815/jipi.v6i3.24914	https://doi.org/10.24815/jipi.v6i3.24914	PROPN
biomedich-1001	299	2	vinsiah	vinsiah	PROPN
biomedich-1001	299	3	,	,	PUNCT
biomedich-1001	299	4	r.	r.	PROPN
biomedich-1001	299	5	,	,	PUNCT
biomedich-1001	299	6	&	&	CCONJ
biomedich-1001	299	7	fadhillah	fadhillah	PROPN
biomedich-1001	299	8	,	,	PUNCT
biomedich-1001	299	9	f.	f.	PROPN
biomedich-1001	299	10	(	(	PUNCT
biomedich-1001	299	11	2018	2018	NUM
biomedich-1001	299	12	)	)	PUNCT
biomedich-1001	299	13	.	.	PUNCT
biomedich-1001	300	1	studi	studi	PROPN
biomedich-1001	300	2	ikatan	ikatan	PROPN
biomedich-1001	300	3	hidrogen	hidrogen	PROPN
biomedich-1001	300	4	sistem	sistem	PROPN
biomedich-1001	300	5	metanol	metanol	PROPN
biomedich-1001	300	6	-	-	PUNCT
biomedich-1001	300	7	metanol	metanol	NOUN
biomedich-1001	300	8	dan	dan	PROPN
biomedich-1001	300	9	etanol	etanol	PROPN
biomedich-1001	300	10	-	-	PUNCT
biomedich-1001	300	11	etanol	etanol	PROPN
biomedich-1001	300	12	dengan	dengan	PROPN
biomedich-1001	300	13	metode	metode	PROPN
biomedich-1001	300	14	molekular	molekular	PROPN
biomedich-1001	300	15	dinamik	dinamik	PROPN
biomedich-1001	300	16	.	.	PUNCT
biomedich-1001	301	1	sainmatika	sainmatika	VERB
biomedich-1001	301	2	:	:	PUNCT
biomedich-1001	301	3	jurnal	jurnal	ADJ
biomedich-1001	301	4	ilmiah	ilmiah	PROPN
biomedich-1001	301	5	matematika	matematika	PROPN
biomedich-1001	301	6	dan	dan	PROPN
biomedich-1001	301	7	ilmu	ilmu	PROPN
biomedich-1001	301	8	pengetahuan	pengetahuan	PROPN
biomedich-1001	301	9	alam	alam	PROPN
biomedich-1001	301	10	,	,	PUNCT
biomedich-1001	301	11	15(1	15(1	NUM
biomedich-1001	301	12	)	)	PUNCT
biomedich-1001	301	13	,	,	PUNCT
biomedich-1001	301	14	14	14	NUM
biomedich-1001	301	15	.	.	PUNCT
biomedich-1001	302	1	https://doi.org/10.31851/sainmatika.v15i1.1739	https://doi.org/10.31851/sainmatika.v15i1.1739	X
biomedich-1001	302	2	yusuf	yusuf	PROPN
biomedich-1001	302	3	,	,	PUNCT
biomedich-1001	302	4	m.	m.	PROPN
biomedich-1001	302	5	j.	j.	PROPN
biomedich-1001	302	6	,	,	PUNCT
biomedich-1001	302	7	widiyana	widiyana	PROPN
biomedich-1001	302	8	,	,	PUNCT
biomedich-1001	302	9	a.	a.	NOUN
biomedich-1001	302	10	p.	p.	PROPN
biomedich-1001	302	11	,	,	PUNCT
biomedich-1001	302	12	&	&	CCONJ
biomedich-1001	302	13	damayanti	damayanti	PROPN
biomedich-1001	302	14	,	,	PUNCT
biomedich-1001	302	15	d.	d.	PROPN
biomedich-1001	302	16	s.	s.	PROPN
biomedich-1001	302	17	(	(	PUNCT
biomedich-1001	302	18	2022	2022	NUM
biomedich-1001	302	19	)	)	PUNCT
biomedich-1001	302	20	.	.	PUNCT
biomedich-1001	303	1	studi	studi	PROPN
biomedich-1001	303	2	in	in	ADP
biomedich-1001	303	3	silico	silico	NOUN
biomedich-1001	303	4	afinitas	afinitas	NOUN
biomedich-1001	303	5	senyawa	senyawa	NOUN
biomedich-1001	303	6	aktif	aktif	PROPN
biomedich-1001	303	7	biji	biji	PROPN
biomedich-1001	303	8	kacang	kacang	PROPN
biomedich-1001	303	9	merah	merah	PROPN
biomedich-1001	303	10	.	.	PUNCT
biomedich-1001	303	11	zubair	zubair	PROPN
biomedich-1001	303	12	,	,	PUNCT
biomedich-1001	303	13	m.	m.	PROPN
biomedich-1001	303	14	s.	s.	PROPN
biomedich-1001	303	15	,	,	PUNCT
biomedich-1001	303	16	maulana	maulana	PROPN
biomedich-1001	303	17	,	,	PUNCT
biomedich-1001	303	18	s.	s.	PROPN
biomedich-1001	303	19	,	,	PUNCT
biomedich-1001	303	20	&	&	CCONJ
biomedich-1001	303	21	mukaddas	mukaddas	PROPN
biomedich-1001	303	22	,	,	PUNCT
biomedich-1001	303	23	a.	a.	NOUN
biomedich-1001	303	24	(	(	PUNCT
biomedich-1001	303	25	2020	2020	NUM
biomedich-1001	303	26	)	)	PUNCT
biomedich-1001	303	27	.	.	PUNCT
biomedich-1001	304	1	penambatan	penambatan	ADJ
biomedich-1001	304	2	molekuler	molekuler	NOUN
biomedich-1001	304	3	dan	dan	PROPN
biomedich-1001	304	4	simulasi	simulasi	PROPN
biomedich-1001	304	5	dinamika	dinamika	PROPN
biomedich-1001	304	6	molekuler	molekuler	PROPN
biomedich-1001	304	7	senyawa	senyawa	PROPN
biomedich-1001	304	8	dari	dari	PROPN
biomedich-1001	304	9	genus	genus	PROPN
biomedich-1001	304	10	nigella	nigella	PROPN
biomedich-1001	304	11	terhadap	terhadap	PROPN
biomedich-1001	304	12	penghambatan	penghambatan	PROPN
biomedich-1001	304	13	aktivitas	aktivita	VERB
biomedich-1001	304	14	enzim	enzim	PROPN
biomedich-1001	304	15	protease	protease	NOUN
biomedich-1001	304	16	hiv-1	hiv-1	PUNCT
biomedich-1001	304	17	:	:	PUNCT
biomedich-1001	304	18	molecular	molecular	ADJ
biomedich-1001	304	19	docking	docking	NOUN
biomedich-1001	304	20	and	and	CCONJ
biomedich-1001	304	21	molecular	molecular	ADJ
biomedich-1001	304	22	dynamics	dynamic	NOUN
biomedich-1001	304	23	simulation	simulation	NOUN
biomedich-1001	304	24	of	of	ADP
biomedich-1001	304	25	compounds	compound	NOUN
biomedich-1001	304	26	from	from	ADP
biomedich-1001	304	27	nigella	nigella	PROPN
biomedich-1001	304	28	genus	genus	PROPN
biomedich-1001	304	29	on	on	ADP
biomedich-1001	304	30	protease	protease	NOUN
biomedich-1001	304	31	hiv-1	hiv-1	X
biomedich-1001	304	32	enzyme	enzyme	NOUN
biomedich-1001	304	33	inhibitors	inhibitor	NOUN
biomedich-1001	304	34	.	.	PUNCT
biomedich-1001	305	1	jurnal	jurnal	ADJ
biomedich-1001	305	2	farmasi	farmasi	PROPN
biomedich-1001	305	3	galenika	galenika	PROPN
biomedich-1001	305	4	(	(	PUNCT
biomedich-1001	305	5	galenika	galenika	PROPN
biomedich-1001	305	6	journal	journal	PROPN
biomedich-1001	305	7	of	of	ADP
biomedich-1001	305	8	pharmacy	pharmacy	NOUN
biomedich-1001	305	9	)	)	PUNCT
biomedich-1001	305	10	(	(	PUNCT
biomedich-1001	305	11	e	e	NOUN
biomedich-1001	305	12	-	-	NOUN
biomedich-1001	305	13	journal	journal	NOUN
biomedich-1001	305	14	)	)	PUNCT
biomedich-1001	305	15	,	,	PUNCT
biomedich-1001	305	16	6(1	6(1	NUM
biomedich-1001	305	17	)	)	PUNCT
biomedich-1001	305	18	,	,	PUNCT
biomedich-1001	305	19	132–140	132–140	NUM
biomedich-1001	305	20	.	.	PUNCT
biomedich-1001	306	1	https://doi.org/10.22487/j24428744.2020.v6.i1.14982	https://doi.org/10.22487/j24428744.2020.v6.i1.14982	NOUN