id	sid	tid	token	lemma	pos
biomedich-166	1	1	biology	biology	NOUN
biomedich-166	1	2	,	,	PUNCT
biomedich-166	1	3	medicine	medicine	NOUN
biomedich-166	1	4	,	,	PUNCT
biomedich-166	1	5	&	&	CCONJ
biomedich-166	1	6	natural	natural	ADJ
biomedich-166	1	7	product	product	NOUN
biomedich-166	1	8	chemistry	chemistry	NOUN
biomedich-166	1	9	issn	issn	VERB
biomedich-166	1	10	2089	2089	NUM
biomedich-166	1	11	-	-	SYM
biomedich-166	1	12	6514	6514	NUM
biomedich-166	1	13	(	(	PUNCT
biomedich-166	1	14	paper	paper	NOUN
biomedich-166	1	15	)	)	PUNCT
biomedich-166	1	16	volume	volume	NOUN
biomedich-166	1	17	10	10	NUM
biomedich-166	1	18	,	,	PUNCT
biomedich-166	1	19	number	number	NOUN
biomedich-166	1	20	2	2	NUM
biomedich-166	1	21	,	,	PUNCT
biomedich-166	1	22	october	october	PROPN
biomedich-166	1	23	2021	2021	NUM
biomedich-166	1	24	|	|	ADV
biomedich-166	1	25	pages	page	NOUN
biomedich-166	1	26	:	:	PUNCT
biomedich-166	1	27	135	135	NUM
biomedich-166	1	28	-	-	SYM
biomedich-166	1	29	140	140	NUM
biomedich-166	1	30	|	|	ADV
biomedich-166	1	31	doi	doi	NOUN
biomedich-166	1	32	:	:	PUNCT
biomedich-166	1	33	10.14421	10.14421	NUM
biomedich-166	1	34	/	/	SYM
biomedich-166	1	35	biomedich.2021.102.135	biomedich.2021.102.135	NOUN
biomedich-166	1	36	-	-	PUNCT
biomedich-166	1	37	140	140	NUM
biomedich-166	1	38	issn	issn	PROPN
biomedich-166	1	39	2540	2540	NUM
biomedich-166	1	40	-	-	SYM
biomedich-166	1	41	9328	9328	NUM
biomedich-166	1	42	(	(	PUNCT
biomedich-166	1	43	online	online	ADV
biomedich-166	1	44	)	)	PUNCT
biomedich-166	1	45	repurposing	repurpose	VERB
biomedich-166	1	46	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	1	47	-	-	PUNCT
biomedich-166	1	48	piperaquine	piperaquine	NOUN
biomedich-166	1	49	-	-	PUNCT
biomedich-166	1	50	doxycycline	doxycycline	NOUN
biomedich-166	1	51	as	as	ADP
biomedich-166	1	52	an	an	DET
biomedich-166	1	53	antimalarial	antimalarial	ADJ
biomedich-166	1	54	drug	drug	NOUN
biomedich-166	1	55	:	:	PUNCT
biomedich-166	1	56	a	a	DET
biomedich-166	1	57	study	study	NOUN
biomedich-166	1	58	in	in	ADP
biomedich-166	1	59	plasmodium	plasmodium	NOUN
biomedich-166	1	60	berghei	berghei	NOUN
biomedich-166	1	61	-	-	PUNCT
biomedich-166	1	62	infected	infect	VERB
biomedich-166	1	63	mice	mice	NOUN
biomedich-166	1	64	udeme	udeme	ADJ
biomedich-166	1	65	owunari	owunari	PROPN
biomedich-166	1	66	georgewill1	georgewill1	NOUN
biomedich-166	1	67	,	,	PUNCT
biomedich-166	1	68	*	*	PROPN
biomedich-166	1	69	,	,	PUNCT
biomedich-166	1	70	elias	elias	PROPN
biomedich-166	1	71	adikwu2	adikwu2	PROPN
biomedich-166	2	1	1department	1department	NUM
biomedich-166	2	2	of	of	ADP
biomedich-166	2	3	pharmacology	pharmacology	NOUN
biomedich-166	2	4	,	,	PUNCT
biomedich-166	2	5	faculty	faculty	NOUN
biomedich-166	2	6	of	of	ADP
biomedich-166	2	7	basic	basic	ADJ
biomedich-166	2	8	clinical	clinical	ADJ
biomedich-166	2	9	sciences	science	NOUN
biomedich-166	2	10	,	,	PUNCT
biomedich-166	2	11	university	university	NOUN
biomedich-166	2	12	of	of	ADP
biomedich-166	2	13	port	port	NOUN
biomedich-166	2	14	harcourt	harcourt	PROPN
biomedich-166	2	15	,	,	PUNCT
biomedich-166	2	16	rivers	river	NOUN
biomedich-166	2	17	state	state	PROPN
biomedich-166	2	18	,	,	PUNCT
biomedich-166	2	19	nigeria	nigeria	PROPN
biomedich-166	3	1	2department	2department	NUM
biomedich-166	3	2	of	of	ADP
biomedich-166	3	3	pharmacology	pharmacology	NOUN
biomedich-166	3	4	and	and	CCONJ
biomedich-166	3	5	toxicology	toxicology	NOUN
biomedich-166	3	6	,	,	PUNCT
biomedich-166	3	7	faculty	faculty	NOUN
biomedich-166	3	8	of	of	ADP
biomedich-166	3	9	pharmacy	pharmacy	NOUN
biomedich-166	3	10	,	,	PUNCT
biomedich-166	3	11	niger	niger	PROPN
biomedich-166	3	12	delta	delta	PROPN
biomedich-166	3	13	university	university	NOUN
biomedich-166	3	14	,	,	PUNCT
biomedich-166	3	15	bayelsa	bayelsa	NOUN
biomedich-166	3	16	state	state	NOUN
biomedich-166	3	17	,	,	PUNCT
biomedich-166	3	18	nigeria	nigeria	PROPN
biomedich-166	3	19	.	.	PUNCT
biomedich-166	4	1	corresponding	correspond	VERB
biomedich-166	4	2	author	author	NOUN
biomedich-166	4	3	*	*	PROPN
biomedich-166	4	4	udgeorgewill@yahoo.com	udgeorgewill@yahoo.com	PROPN
biomedich-166	4	5	manuscript	manuscript	NOUN
biomedich-166	4	6	received	receive	VERB
biomedich-166	4	7	:	:	PUNCT
biomedich-166	4	8	06	06	NUM
biomedich-166	4	9	december	december	PROPN
biomedich-166	4	10	2021	2021	NUM
biomedich-166	4	11	.	.	PUNCT
biomedich-166	5	1	revision	revision	NOUN
biomedich-166	5	2	accepted	accept	VERB
biomedich-166	5	3	:	:	PUNCT
biomedich-166	5	4	12	12	NUM
biomedich-166	5	5	december	december	NOUN
biomedich-166	5	6	,	,	PUNCT
biomedich-166	5	7	2021	2021	NUM
biomedich-166	5	8	.	.	PUNCT
biomedich-166	6	1	published	publish	VERB
biomedich-166	6	2	:	:	PUNCT
biomedich-166	6	3	16	16	NUM
biomedich-166	6	4	december	december	PROPN
biomedich-166	6	5	,	,	PUNCT
biomedich-166	6	6	2021	2021	NUM
biomedich-166	6	7	.	.	PUNCT
biomedich-166	7	1	abstract	abstract	ADJ
biomedich-166	7	2	artemisinin	artemisinin	NOUN
biomedich-166	7	3	-	-	PUNCT
biomedich-166	7	4	based	base	VERB
biomedich-166	7	5	combination	combination	NOUN
biomedich-166	7	6	(	(	PUNCT
biomedich-166	7	7	act	act	PROPN
biomedich-166	7	8	)	)	PUNCT
biomedich-166	7	9	therapy	therapy	NOUN
biomedich-166	7	10	is	be	AUX
biomedich-166	7	11	the	the	DET
biomedich-166	7	12	mainstay	mainstay	NOUN
biomedich-166	7	13	for	for	ADP
biomedich-166	7	14	malaria	malaria	NOUN
biomedich-166	7	15	treatment	treatment	NOUN
biomedich-166	7	16	.	.	PUNCT
biomedich-166	8	1	however	however	ADV
biomedich-166	8	2	,	,	PUNCT
biomedich-166	8	3	plasmodium	plasmodium	NOUN
biomedich-166	8	4	parasite	parasite	NOUN
biomedich-166	8	5	with	with	ADP
biomedich-166	8	6	decreased	decrease	VERB
biomedich-166	8	7	susceptibility	susceptibility	NOUN
biomedich-166	8	8	to	to	PART
biomedich-166	8	9	act	act	VERB
biomedich-166	8	10	has	have	AUX
biomedich-166	8	11	emerged	emerge	VERB
biomedich-166	8	12	.	.	PUNCT
biomedich-166	9	1	hence	hence	ADV
biomedich-166	9	2	,	,	PUNCT
biomedich-166	9	3	it	it	PRON
biomedich-166	9	4	is	be	AUX
biomedich-166	9	5	imperative	imperative	ADJ
biomedich-166	9	6	to	to	PART
biomedich-166	9	7	discover	discover	VERB
biomedich-166	9	8	new	new	ADJ
biomedich-166	9	9	drugs	drug	NOUN
biomedich-166	9	10	or	or	CCONJ
biomedich-166	9	11	explore	explore	VERB
biomedich-166	9	12	new	new	ADJ
biomedich-166	9	13	drug	drug	NOUN
biomedich-166	9	14	combinations	combination	NOUN
biomedich-166	9	15	that	that	PRON
biomedich-166	9	16	can	can	AUX
biomedich-166	9	17	decrease	decrease	VERB
biomedich-166	9	18	plasmodium	plasmodium	NOUN
biomedich-166	9	19	parasite	parasite	NOUN
biomedich-166	9	20	resistance	resistance	NOUN
biomedich-166	9	21	.	.	PUNCT
biomedich-166	10	1	this	this	DET
biomedich-166	10	2	study	study	NOUN
biomedich-166	10	3	assessed	assess	VERB
biomedich-166	10	4	the	the	DET
biomedich-166	10	5	antiplasmodial	antiplasmodial	ADJ
biomedich-166	10	6	activity	activity	NOUN
biomedich-166	10	7	of	of	ADP
biomedich-166	10	8	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	10	9	-	-	PUNCT
biomedich-166	10	10	piperaquinedoxycycline	piperaquinedoxycycline	NOUN
biomedich-166	10	11	(	(	PUNCT
biomedich-166	10	12	d	d	NOUN
biomedich-166	10	13	-	-	PUNCT
biomedich-166	10	14	pdx	pdx	NOUN
biomedich-166	10	15	)	)	PUNCT
biomedich-166	10	16	on	on	ADP
biomedich-166	10	17	mice	mouse	NOUN
biomedich-166	10	18	infected	infect	VERB
biomedich-166	10	19	with	with	ADP
biomedich-166	10	20	plasmodium	plasmodium	NOUN
biomedich-166	10	21	berghei	berghei	NOUN
biomedich-166	10	22	.	.	PUNCT
biomedich-166	11	1	swiss	swiss	ADJ
biomedich-166	11	2	albino	albino	NOUN
biomedich-166	11	3	mice	mouse	NOUN
biomedich-166	11	4	(	(	PUNCT
biomedich-166	11	5	25	25	NUM
biomedich-166	11	6	-	-	SYM
biomedich-166	11	7	30	30	NUM
biomedich-166	11	8	g	g	NOUN
biomedich-166	11	9	)	)	PUNCT
biomedich-166	11	10	of	of	ADP
biomedich-166	11	11	both	both	DET
biomedich-166	11	12	sexes	sex	NOUN
biomedich-166	11	13	inoculated	inoculate	VERB
biomedich-166	11	14	with	with	ADP
biomedich-166	11	15	1x107	1x107	NUM
biomedich-166	11	16	plasmodium	plasmodium	NOUN
biomedich-166	11	17	berghei	berghei	NOUN
biomedich-166	11	18	intraperitoneally	intraperitoneally	ADV
biomedich-166	11	19	were	be	AUX
biomedich-166	11	20	used	use	VERB
biomedich-166	11	21	.	.	PUNCT
biomedich-166	12	1	the	the	DET
biomedich-166	12	2	mice	mouse	NOUN
biomedich-166	12	3	were	be	AUX
biomedich-166	12	4	randomly	randomly	ADV
biomedich-166	12	5	grouped	group	VERB
biomedich-166	12	6	and	and	CCONJ
biomedich-166	12	7	orally	orally	ADV
biomedich-166	12	8	treated	treat	VERB
biomedich-166	12	9	with	with	ADP
biomedich-166	12	10	dx	dx	PROPN
biomedich-166	12	11	(	(	PUNCT
biomedich-166	12	12	2.2	2.2	NUM
biomedich-166	12	13	mg	mg	PROPN
biomedich-166	12	14	/	/	SYM
biomedich-166	12	15	kg	kg	PROPN
biomedich-166	12	16	)	)	PUNCT
biomedich-166	12	17	,	,	PUNCT
biomedich-166	13	1	d	d	X
biomedich-166	13	2	-	-	PUNCT
biomedich-166	13	3	p	p	X
biomedich-166	13	4	(	(	PUNCT
biomedich-166	13	5	1.71/13.7	1.71/13.7	NUM
biomedich-166	13	6	mg	mg	PROPN
biomedich-166	13	7	/	/	SYM
biomedich-166	13	8	kg	kg	NOUN
biomedich-166	13	9	)	)	PUNCT
biomedich-166	13	10	and	and	CCONJ
biomedich-166	13	11	d	d	X
biomedich-166	13	12	-	-	PUNCT
biomedich-166	13	13	pdx	pdx	PROPN
biomedich-166	13	14	daily	daily	NOUN
biomedich-166	13	15	in	in	ADP
biomedich-166	13	16	curative	curative	ADJ
biomedich-166	13	17	,	,	PUNCT
biomedich-166	13	18	suppressive	suppressive	ADJ
biomedich-166	13	19	and	and	CCONJ
biomedich-166	13	20	prophylactic	prophylactic	ADJ
biomedich-166	13	21	studies	study	NOUN
biomedich-166	13	22	.	.	PUNCT
biomedich-166	14	1	the	the	DET
biomedich-166	14	2	negative	negative	ADJ
biomedich-166	14	3	and	and	CCONJ
biomedich-166	14	4	the	the	DET
biomedich-166	14	5	positive	positive	ADJ
biomedich-166	14	6	controls	control	NOUN
biomedich-166	14	7	were	be	AUX
biomedich-166	14	8	treated	treat	VERB
biomedich-166	14	9	daily	daily	ADV
biomedich-166	14	10	with	with	ADP
biomedich-166	14	11	normal	normal	ADJ
biomedich-166	14	12	saline	saline	NOUN
biomedich-166	14	13	(	(	PUNCT
biomedich-166	14	14	0.2ml	0.2ml	NUM
biomedich-166	14	15	)	)	PUNCT
biomedich-166	14	16	and	and	CCONJ
biomedich-166	14	17	chloroquine	chloroquine	NOUN
biomedich-166	14	18	(	(	PUNCT
biomedich-166	14	19	cq	cq	NOUN
biomedich-166	14	20	)	)	PUNCT
biomedich-166	14	21	(	(	PUNCT
biomedich-166	14	22	10mg	10mg	NOUN
biomedich-166	14	23	/	/	SYM
biomedich-166	14	24	kg	kg	NOUN
biomedich-166	14	25	)	)	PUNCT
biomedich-166	14	26	,	,	PUNCT
biomedich-166	14	27	respectively	respectively	ADV
biomedich-166	14	28	.	.	PUNCT
biomedich-166	15	1	after	after	ADP
biomedich-166	15	2	treatment	treatment	NOUN
biomedich-166	15	3	,	,	PUNCT
biomedich-166	15	4	blood	blood	NOUN
biomedich-166	15	5	samples	sample	NOUN
biomedich-166	15	6	were	be	AUX
biomedich-166	15	7	assessed	assess	VERB
biomedich-166	15	8	for	for	ADP
biomedich-166	15	9	percentage	percentage	NOUN
biomedich-166	15	10	parasitemia	parasitemia	NOUN
biomedich-166	15	11	,	,	PUNCT
biomedich-166	15	12	hematological	hematological	ADJ
biomedich-166	15	13	and	and	CCONJ
biomedich-166	15	14	lipid	lipid	NOUN
biomedich-166	15	15	parameters	parameter	NOUN
biomedich-166	15	16	.	.	PUNCT
biomedich-166	16	1	the	the	DET
biomedich-166	16	2	mice	mouse	NOUN
biomedich-166	16	3	were	be	AUX
biomedich-166	16	4	observed	observe	VERB
biomedich-166	16	5	for	for	ADP
biomedich-166	16	6	mean	mean	ADJ
biomedich-166	16	7	survival	survival	NOUN
biomedich-166	16	8	time	time	NOUN
biomedich-166	16	9	.	.	PUNCT
biomedich-166	17	1	d	d	X
biomedich-166	17	2	-	-	PUNCT
biomedich-166	17	3	p	p	X
biomedich-166	17	4	,	,	PUNCT
biomedich-166	17	5	dx	dx	PROPN
biomedich-166	17	6	,	,	PUNCT
biomedich-166	17	7	and	and	CCONJ
biomedich-166	17	8	d	d	X
biomedich-166	17	9	-	-	ADJ
biomedich-166	17	10	p	p	PROPN
biomedich-166	17	11	-	-	PUNCT
biomedich-166	17	12	dx	dx	PROPN
biomedich-166	17	13	produced	produce	VERB
biomedich-166	17	14	significant	significant	ADJ
biomedich-166	17	15	decreases	decrease	NOUN
biomedich-166	17	16	in	in	ADP
biomedich-166	17	17	percentage	percentage	NOUN
biomedich-166	17	18	parasitemia	parasitemia	NOUN
biomedich-166	17	19	at	at	ADP
biomedich-166	17	20	p<0.05	p<0.05	NOUN
biomedich-166	17	21	,	,	PUNCT
biomedich-166	17	22	p<0.01	p<0.01	PROPN
biomedich-166	17	23	and	and	CCONJ
biomedich-166	17	24	p<0.001	p<0.001	PROPN
biomedich-166	17	25	,	,	PUNCT
biomedich-166	17	26	respectively	respectively	ADV
biomedich-166	17	27	when	when	SCONJ
biomedich-166	17	28	compared	compare	VERB
biomedich-166	17	29	to	to	ADP
biomedich-166	17	30	negative	negative	ADJ
biomedich-166	17	31	control	control	NOUN
biomedich-166	17	32	.	.	PUNCT
biomedich-166	18	1	in	in	ADP
biomedich-166	18	2	the	the	DET
biomedich-166	18	3	curative	curative	ADJ
biomedich-166	18	4	study	study	NOUN
biomedich-166	18	5	,	,	PUNCT
biomedich-166	18	6	d	d	X
biomedich-166	18	7	-	-	PUNCT
biomedich-166	18	8	p	p	X
biomedich-166	18	9	,	,	PUNCT
biomedich-166	18	10	dx	dx	PROPN
biomedich-166	18	11	,	,	PUNCT
biomedich-166	18	12	and	and	CCONJ
biomedich-166	18	13	d	d	X
biomedich-166	18	14	-	-	ADJ
biomedich-166	18	15	p	p	PROPN
biomedich-166	18	16	-	-	PUNCT
biomedich-166	18	17	dx	dx	NOUN
biomedich-166	18	18	produced	produce	VERB
biomedich-166	18	19	64.9	64.9	NUM
biomedich-166	18	20	%	%	NOUN
biomedich-166	18	21	,	,	PUNCT
biomedich-166	18	22	71.1	71.1	NUM
biomedich-166	18	23	%	%	NOUN
biomedich-166	18	24	,	,	PUNCT
biomedich-166	18	25	and	and	CCONJ
biomedich-166	18	26	93.6	93.6	NUM
biomedich-166	18	27	%	%	NOUN
biomedich-166	18	28	parasitemia	parasitemia	NOUN
biomedich-166	18	29	inhibitions	inhibition	NOUN
biomedich-166	18	30	when	when	SCONJ
biomedich-166	18	31	compared	compare	VERB
biomedich-166	18	32	to	to	ADP
biomedich-166	18	33	75.0	75.0	NUM
biomedich-166	18	34	%	%	NOUN
biomedich-166	18	35	inhibition	inhibition	NOUN
biomedich-166	18	36	produced	produce	VERB
biomedich-166	18	37	by	by	ADP
biomedich-166	18	38	cq	cq	PROPN
biomedich-166	18	39	.	.	PROPN
biomedich-166	18	40	plasmodium	plasmodium	NOUN
biomedich-166	18	41	berghei	berghei	PROPN
biomedich-166	18	42	-induced	-induce	VERB
biomedich-166	18	43	alterations	alteration	NOUN
biomedich-166	18	44	in	in	ADP
biomedich-166	18	45	packed	pack	VERB
biomedich-166	18	46	cell	cell	NOUN
biomedich-166	18	47	volume	volume	NOUN
biomedich-166	18	48	,	,	PUNCT
biomedich-166	18	49	white	white	ADJ
biomedich-166	18	50	blood	blood	NOUN
biomedich-166	18	51	cells	cell	NOUN
biomedich-166	18	52	,	,	PUNCT
biomedich-166	18	53	red	red	ADJ
biomedich-166	18	54	blood	blood	NOUN
biomedich-166	18	55	cells	cell	NOUN
biomedich-166	18	56	,	,	PUNCT
biomedich-166	18	57	hemoglobin	hemoglobin	NOUN
biomedich-166	18	58	,	,	PUNCT
biomedich-166	18	59	high	high	ADJ
biomedich-166	18	60	-	-	PUNCT
biomedich-166	18	61	density	density	NOUN
biomedich-166	18	62	lipoprotein	lipoprotein	ADJ
biomedich-166	18	63	cholesterol	cholesterol	NOUN
biomedich-166	18	64	,	,	PUNCT
biomedich-166	18	65	total	total	ADJ
biomedich-166	18	66	cholesterol	cholesterol	NOUN
biomedich-166	18	67	,	,	PUNCT
biomedich-166	18	68	low	low	ADJ
biomedich-166	18	69	-	-	PUNCT
biomedich-166	18	70	density	density	NOUN
biomedich-166	18	71	lipoprotein	lipoprotein	ADJ
biomedich-166	18	72	cholesterol	cholesterol	NOUN
biomedich-166	18	73	,	,	PUNCT
biomedich-166	18	74	and	and	CCONJ
biomedich-166	18	75	triglyceride	triglyceride	ADJ
biomedich-166	18	76	levels	level	NOUN
biomedich-166	18	77	were	be	AUX
biomedich-166	18	78	significantly	significantly	ADV
biomedich-166	18	79	restored	restore	VERB
biomedich-166	18	80	by	by	ADP
biomedich-166	18	81	dx	dx	PROPN
biomedich-166	18	82	(	(	PUNCT
biomedich-166	18	83	p<0.05	p<0.05	PROPN
biomedich-166	18	84	)	)	PUNCT
biomedich-166	18	85	and	and	CCONJ
biomedich-166	18	86	d	d	X
biomedich-166	18	87	-	-	PUNCT
biomedich-166	18	88	p	p	X
biomedich-166	18	89	(	(	PUNCT
biomedich-166	18	90	p<0.01	p<0.01	PROPN
biomedich-166	18	91	)	)	PUNCT
biomedich-166	18	92	and	and	CCONJ
biomedich-166	18	93	d	d	X
biomedich-166	18	94	-	-	PUNCT
biomedich-166	18	95	p	p	X
biomedich-166	18	96	-	-	PUNCT
biomedich-166	18	97	dx	dx	PROPN
biomedich-166	18	98	(	(	PUNCT
biomedich-166	18	99	p<0.001	p<0.001	PROPN
biomedich-166	18	100	)	)	PUNCT
biomedich-166	18	101	when	when	SCONJ
biomedich-166	18	102	compared	compare	VERB
biomedich-166	18	103	to	to	ADP
biomedich-166	18	104	the	the	DET
biomedich-166	18	105	negative	negative	ADJ
biomedich-166	18	106	control	control	NOUN
biomedich-166	18	107	.	.	PUNCT
biomedich-166	19	1	d	d	X
biomedich-166	19	2	-	-	PUNCT
biomedich-166	19	3	p	p	NOUN
biomedich-166	19	4	-	-	PUNCT
biomedich-166	19	5	dx	dx	PROPN
biomedich-166	19	6	showed	show	VERB
biomedich-166	19	7	significant	significant	ADJ
biomedich-166	19	8	antiplasmodial	antiplasmodial	ADJ
biomedich-166	19	9	activity	activity	NOUN
biomedich-166	19	10	against	against	ADP
biomedich-166	19	11	plasmodium	plasmodium	NOUN
biomedich-166	19	12	bergheiinfected	bergheiinfecte	VERB
biomedich-166	19	13	mice	mouse	NOUN
biomedich-166	19	14	.	.	PUNCT
biomedich-166	20	1	it	it	PRON
biomedich-166	20	2	may	may	AUX
biomedich-166	20	3	be	be	AUX
biomedich-166	20	4	clinically	clinically	ADV
biomedich-166	20	5	useful	useful	ADJ
biomedich-166	20	6	for	for	ADP
biomedich-166	20	7	the	the	DET
biomedich-166	20	8	treatment	treatment	NOUN
biomedich-166	20	9	of	of	ADP
biomedich-166	20	10	malaria	malaria	NOUN
biomedich-166	20	11	.	.	PUNCT
biomedich-166	21	1	keywords	keyword	NOUN
biomedich-166	21	2	;	;	PUNCT
biomedich-166	21	3	artemisinins	artemisinin	NOUN
biomedich-166	21	4	;	;	PUNCT
biomedich-166	21	5	doxycycline	doxycycline	NOUN
biomedich-166	21	6	;	;	PUNCT
biomedich-166	21	7	malaria	malaria	NOUN
biomedich-166	21	8	;	;	PUNCT
biomedich-166	21	9	repurposing	repurpose	VERB
biomedich-166	21	10	;	;	PUNCT
biomedich-166	21	11	resistance	resistance	NOUN
biomedich-166	21	12	.	.	PUNCT
biomedich-166	22	1	introduction	introduction	NOUN
biomedich-166	22	2	world	world	PROPN
biomedich-166	22	3	health	health	PROPN
biomedich-166	22	4	organization	organization	NOUN
biomedich-166	22	5	(	(	PUNCT
biomedich-166	22	6	who	who	PRON
biomedich-166	22	7	)	)	PUNCT
biomedich-166	22	8	estimates	estimate	VERB
biomedich-166	22	9	that	that	SCONJ
biomedich-166	22	10	nearly	nearly	ADV
biomedich-166	22	11	half	half	NOUN
biomedich-166	22	12	of	of	ADP
biomedich-166	22	13	the	the	DET
biomedich-166	22	14	world	world	NOUN
biomedich-166	22	15	’s	’s	PART
biomedich-166	22	16	population	population	NOUN
biomedich-166	22	17	lived	live	VERB
biomedich-166	22	18	in	in	ADP
biomedich-166	22	19	malaria	malaria	ADJ
biomedich-166	22	20	endemic	endemic	ADJ
biomedich-166	22	21	areas	area	NOUN
biomedich-166	22	22	(	(	PUNCT
biomedich-166	22	23	who	who	PRON
biomedich-166	22	24	,	,	PUNCT
biomedich-166	22	25	2016	2016	NUM
biomedich-166	22	26	)	)	PUNCT
biomedich-166	22	27	.	.	PUNCT
biomedich-166	23	1	malaria	malaria	NOUN
biomedich-166	23	2	,	,	PUNCT
biomedich-166	23	3	a	a	DET
biomedich-166	23	4	plasmodium	plasmodium	NOUN
biomedich-166	23	5	parasite	parasite	NOUN
biomedich-166	23	6	infection	infection	NOUN
biomedich-166	23	7	is	be	AUX
biomedich-166	23	8	one	one	NUM
biomedich-166	23	9	of	of	ADP
biomedich-166	23	10	the	the	DET
biomedich-166	23	11	greatest	great	ADJ
biomedich-166	23	12	health	health	NOUN
biomedich-166	23	13	challenges	challenge	NOUN
biomedich-166	23	14	in	in	ADP
biomedich-166	23	15	tropical	tropical	ADJ
biomedich-166	23	16	regions	region	NOUN
biomedich-166	23	17	,	,	PUNCT
biomedich-166	23	18	despite	despite	SCONJ
biomedich-166	23	19	the	the	DET
biomedich-166	23	20	availability	availability	NOUN
biomedich-166	23	21	of	of	ADP
biomedich-166	23	22	antimalarial	antimalarial	ADJ
biomedich-166	23	23	drugs	drug	NOUN
biomedich-166	23	24	,	,	PUNCT
biomedich-166	23	25	mosquito	mosquito	ADJ
biomedich-166	23	26	repellents	repellent	NOUN
biomedich-166	23	27	and	and	CCONJ
biomedich-166	23	28	insecticide	insecticide	NOUN
biomedich-166	23	29	-	-	PUNCT
biomedich-166	23	30	treated	treat	VERB
biomedich-166	23	31	nets	net	NOUN
biomedich-166	23	32	.	.	PUNCT
biomedich-166	24	1	malaria	malaria	NOUN
biomedich-166	24	2	chemotherapy	chemotherapy	NOUN
biomedich-166	24	3	remains	remain	VERB
biomedich-166	24	4	a	a	DET
biomedich-166	24	5	major	major	ADJ
biomedich-166	24	6	focus	focus	NOUN
biomedich-166	24	7	of	of	ADP
biomedich-166	24	8	research	research	NOUN
biomedich-166	24	9	,	,	PUNCT
biomedich-166	24	10	and	and	CCONJ
biomedich-166	24	11	new	new	ADJ
biomedich-166	24	12	molecules	molecule	NOUN
biomedich-166	24	13	are	be	AUX
biomedich-166	24	14	being	be	AUX
biomedich-166	24	15	discovered	discover	VERB
biomedich-166	24	16	prior	prior	ADV
biomedich-166	24	17	to	to	ADP
biomedich-166	24	18	the	the	DET
biomedich-166	24	19	emergence	emergence	NOUN
biomedich-166	24	20	of	of	ADP
biomedich-166	24	21	drug	drug	NOUN
biomedich-166	24	22	-	-	PUNCT
biomedich-166	24	23	resistant	resistant	ADJ
biomedich-166	24	24	strains	strain	NOUN
biomedich-166	24	25	of	of	ADP
biomedich-166	24	26	plasmodium	plasmodium	NOUN
biomedich-166	24	27	parasite	parasite	NOUN
biomedich-166	24	28	(	(	PUNCT
biomedich-166	24	29	gaillard	gaillard	PROPN
biomedich-166	24	30	et	et	PROPN
biomedich-166	24	31	al	al	PROPN
biomedich-166	24	32	.	.	PROPN
biomedich-166	24	33	,	,	PUNCT
biomedich-166	24	34	2015	2015	NUM
biomedich-166	24	35	)	)	PUNCT
biomedich-166	24	36	.	.	PUNCT
biomedich-166	25	1	the	the	DET
biomedich-166	25	2	use	use	NOUN
biomedich-166	25	3	of	of	ADP
biomedich-166	25	4	antimalarial	antimalarial	ADJ
biomedich-166	25	5	drugs	drug	NOUN
biomedich-166	25	6	is	be	AUX
biomedich-166	25	7	faced	face	VERB
biomedich-166	25	8	with	with	ADP
biomedich-166	25	9	the	the	DET
biomedich-166	25	10	development	development	NOUN
biomedich-166	25	11	of	of	ADP
biomedich-166	25	12	resistance	resistance	NOUN
biomedich-166	25	13	from	from	ADP
biomedich-166	25	14	plasmodium	plasmodium	NOUN
biomedich-166	25	15	falciparum	falciparum	NOUN
biomedich-166	25	16	in	in	ADP
biomedich-166	25	17	primarily	primarily	ADV
biomedich-166	25	18	endemic	endemic	ADJ
biomedich-166	25	19	areas	area	NOUN
biomedich-166	25	20	.	.	PUNCT
biomedich-166	26	1	other	other	ADJ
biomedich-166	26	2	challenges	challenge	NOUN
biomedich-166	26	3	include	include	VERB
biomedich-166	26	4	financial	financial	ADJ
biomedich-166	26	5	costs	cost	NOUN
biomedich-166	26	6	,	,	PUNCT
biomedich-166	26	7	contraindications	contraindication	NOUN
biomedich-166	26	8	,	,	PUNCT
biomedich-166	26	9	and	and	CCONJ
biomedich-166	26	10	clinical	clinical	ADJ
biomedich-166	26	11	tolerance	tolerance	NOUN
biomedich-166	26	12	(	(	PUNCT
biomedich-166	26	13	gaillard	gaillard	PROPN
biomedich-166	26	14	et	et	PROPN
biomedich-166	26	15	al	al	PROPN
biomedich-166	26	16	.	.	PROPN
biomedich-166	26	17	,	,	PUNCT
biomedich-166	26	18	2015	2015	NUM
biomedich-166	26	19	)	)	PUNCT
biomedich-166	26	20	.	.	PUNCT
biomedich-166	27	1	doxycycline	doxycycline	NOUN
biomedich-166	27	2	(	(	PUNCT
biomedich-166	27	3	dx	dx	PROPN
biomedich-166	27	4	)	)	PUNCT
biomedich-166	27	5	,	,	PUNCT
biomedich-166	27	6	a	a	DET
biomedich-166	27	7	broad	broad	ADJ
biomedich-166	27	8	-	-	PUNCT
biomedich-166	27	9	spectrum	spectrum	NOUN
biomedich-166	27	10	bacteriostatic	bacteriostatic	ADJ
biomedich-166	27	11	agent	agent	NOUN
biomedich-166	27	12	is	be	AUX
biomedich-166	27	13	synthetically	synthetically	ADV
biomedich-166	27	14	obtained	obtain	VERB
biomedich-166	27	15	from	from	ADP
biomedich-166	27	16	naturally	naturally	ADV
biomedich-166	27	17	occurring	occur	VERB
biomedich-166	27	18	tetracyclines	tetracycline	NOUN
biomedich-166	27	19	produced	produce	VERB
biomedich-166	27	20	by	by	ADP
biomedich-166	27	21	streptomyces	streptomyce	NOUN
biomedich-166	27	22	sp	sp	NOUN
biomedich-166	27	23	.	.	PUNCT
biomedich-166	28	1	(	(	PUNCT
biomedich-166	28	2	mcevoy	mcevoy	PROPN
biomedich-166	28	3	et	et	PROPN
biomedich-166	28	4	al	al	PROPN
biomedich-166	28	5	.	.	PROPN
biomedich-166	28	6	,	,	PUNCT
biomedich-166	28	7	2008	2008	NUM
biomedich-166	28	8	)	)	PUNCT
biomedich-166	28	9	.	.	PUNCT
biomedich-166	29	1	it	it	PRON
biomedich-166	29	2	acts	act	VERB
biomedich-166	29	3	by	by	ADP
biomedich-166	29	4	binding	bind	VERB
biomedich-166	29	5	to	to	ADP
biomedich-166	29	6	several	several	ADJ
biomedich-166	29	7	proteins	protein	NOUN
biomedich-166	29	8	in	in	ADP
biomedich-166	29	9	the	the	DET
biomedich-166	29	10	30s	30	NOUN
biomedich-166	29	11	ribosomal	ribosomal	VERB
biomedich-166	29	12	small	small	ADJ
biomedich-166	29	13	subunit	subunit	NOUN
biomedich-166	29	14	and	and	CCONJ
biomedich-166	29	15	to	to	ADP
biomedich-166	29	16	different	different	ADJ
biomedich-166	29	17	ribonucleic	ribonucleic	ADJ
biomedich-166	29	18	acids	acid	NOUN
biomedich-166	29	19	in	in	ADP
biomedich-166	29	20	the	the	DET
biomedich-166	29	21	16s	16s	PROPN
biomedich-166	29	22	ribosomal	ribosomal	NOUN
biomedich-166	29	23	rna	rna	PROPN
biomedich-166	29	24	.	.	PUNCT
biomedich-166	30	1	in	in	ADP
biomedich-166	30	2	addition	addition	NOUN
biomedich-166	30	3	to	to	ADP
biomedich-166	30	4	its	its	PRON
biomedich-166	30	5	antimicrobial	antimicrobial	ADJ
biomedich-166	30	6	activity	activity	NOUN
biomedich-166	30	7	,	,	PUNCT
biomedich-166	30	8	it	it	PRON
biomedich-166	30	9	is	be	AUX
biomedich-166	30	10	a	a	DET
biomedich-166	30	11	partially	partially	ADV
biomedich-166	30	12	efficacious	efficacious	ADJ
biomedich-166	30	13	prophylactic	prophylactic	ADJ
biomedich-166	30	14	drug	drug	NOUN
biomedich-166	30	15	with	with	ADP
biomedich-166	30	16	activity	activity	NOUN
biomedich-166	30	17	against	against	ADP
biomedich-166	30	18	liver	liver	NOUN
biomedich-166	30	19	stage	stage	NOUN
biomedich-166	30	20	of	of	ADP
biomedich-166	30	21	plasmodium	plasmodium	NOUN
biomedich-166	30	22	and	and	CCONJ
biomedich-166	30	23	blood	blood	NOUN
biomedich-166	30	24	schizontocides	schizontocide	NOUN
biomedich-166	30	25	.	.	PUNCT
biomedich-166	31	1	it	it	PRON
biomedich-166	31	2	is	be	AUX
biomedich-166	31	3	highly	highly	ADV
biomedich-166	31	4	effective	effective	ADJ
biomedich-166	31	5	for	for	ADP
biomedich-166	31	6	the	the	DET
biomedich-166	31	7	prevention	prevention	NOUN
biomedich-166	31	8	of	of	ADP
biomedich-166	31	9	malaria	malaria	NOUN
biomedich-166	31	10	.	.	PUNCT
biomedich-166	32	1	the	the	DET
biomedich-166	32	2	u.s	u.s	PROPN
biomedich-166	32	3	.	.	PROPN
biomedich-166	32	4	food	food	PROPN
biomedich-166	32	5	and	and	CCONJ
biomedich-166	32	6	drug	drug	PROPN
biomedich-166	32	7	administration	administration	PROPN
biomedich-166	32	8	(	(	PUNCT
biomedich-166	32	9	fda	fda	PROPN
biomedich-166	32	10	)	)	PUNCT
biomedich-166	32	11	approved	approve	VERB
biomedich-166	32	12	the	the	DET
biomedich-166	32	13	use	use	NOUN
biomedich-166	32	14	of	of	ADP
biomedich-166	32	15	dx	dx	PROPN
biomedich-166	32	16	for	for	ADP
biomedich-166	32	17	prophylaxis	prophylaxis	NOUN
biomedich-166	32	18	of	of	ADP
biomedich-166	32	19	plasmodium	plasmodium	NOUN
biomedich-166	32	20	falciparum	falciparum	NOUN
biomedich-166	32	21	in	in	ADP
biomedich-166	32	22	short	short	ADJ
biomedich-166	32	23	-	-	PUNCT
biomedich-166	32	24	term	term	NOUN
biomedich-166	32	25	travelers	traveler	NOUN
biomedich-166	32	26	to	to	ADP
biomedich-166	32	27	areas	area	NOUN
biomedich-166	32	28	with	with	ADP
biomedich-166	32	29	chloroquine	chloroquine	NOUN
biomedich-166	32	30	or	or	CCONJ
biomedich-166	32	31	pyrimethaminesulfadoxine	pyrimethaminesulfadoxine	ADV
biomedich-166	32	32	-	-	PUNCT
biomedich-166	32	33	resistant	resistant	ADJ
biomedich-166	32	34	strains	strain	NOUN
biomedich-166	32	35	(	(	PUNCT
biomedich-166	32	36	tan	tan	NOUN
biomedich-166	32	37	et	et	NOUN
biomedich-166	32	38	al	al	PROPN
biomedich-166	32	39	.	.	PROPN
biomedich-166	32	40	,	,	PUNCT
biomedich-166	32	41	2011	2011	NUM
biomedich-166	32	42	)	)	PUNCT
biomedich-166	32	43	.	.	PUNCT
biomedich-166	33	1	dx	dx	PROPN
biomedich-166	33	2	can	can	AUX
biomedich-166	33	3	be	be	AUX
biomedich-166	33	4	used	use	VERB
biomedich-166	33	5	for	for	ADP
biomedich-166	33	6	the	the	DET
biomedich-166	33	7	treatment	treatment	NOUN
biomedich-166	33	8	of	of	ADP
biomedich-166	33	9	malaria	malaria	NOUN
biomedich-166	33	10	in	in	ADP
biomedich-166	33	11	children	child	NOUN
biomedich-166	33	12	less	less	ADJ
biomedich-166	33	13	than	than	ADP
biomedich-166	33	14	8	8	NUM
biomedich-166	33	15	years	year	NOUN
biomedich-166	33	16	old	old	ADJ
biomedich-166	33	17	and	and	CCONJ
biomedich-166	33	18	non	non	ADJ
biomedich-166	33	19	-	-	ADJ
biomedich-166	33	20	pregnant	pregnant	ADJ
biomedich-166	33	21	adults	adult	NOUN
biomedich-166	33	22	in	in	ADP
biomedich-166	33	23	combination	combination	NOUN
biomedich-166	33	24	with	with	ADP
biomedich-166	33	25	quinine	quinine	ADJ
biomedich-166	33	26	sulfate	sulfate	NOUN
biomedich-166	33	27	for	for	ADP
biomedich-166	33	28	uncomplicated	uncomplicated	ADJ
biomedich-166	33	29	and	and	CCONJ
biomedich-166	33	30	chloroquineresistant	chloroquineresistant	ADJ
biomedich-166	33	31	plasmodium	plasmodium	NOUN
biomedich-166	33	32	falciparum	falciparum	NOUN
biomedich-166	33	33	.	.	PUNCT
biomedich-166	34	1	it	it	PRON
biomedich-166	34	2	is	be	AUX
biomedich-166	34	3	also	also	ADV
biomedich-166	34	4	used	use	VERB
biomedich-166	34	5	with	with	ADP
biomedich-166	34	6	primaquine	primaquine	NOUN
biomedich-166	34	7	and	and	CCONJ
biomedich-166	34	8	quinine	quinine	ADJ
biomedich-166	34	9	sulfate	sulfate	NOUN
biomedich-166	34	10	for	for	ADP
biomedich-166	34	11	uncomplicated	uncomplicated	ADJ
biomedich-166	34	12	chloroquine	chloroquine	NOUN
biomedich-166	34	13	-	-	PUNCT
biomedich-166	34	14	resistant	resistant	ADJ
biomedich-166	34	15	plasmodium	plasmodium	NOUN
biomedich-166	34	16	vivax	vivax	NOUN
biomedich-166	34	17	and	and	CCONJ
biomedich-166	34	18	with	with	ADP
biomedich-166	34	19	parenteral	parenteral	ADJ
biomedich-166	34	20	quinidine	quinidine	NOUN
biomedich-166	34	21	for	for	ADP
biomedich-166	34	22	severe	severe	ADJ
biomedich-166	34	23	malaria	malaria	NOUN
biomedich-166	34	24	(	(	PUNCT
biomedich-166	34	25	griffith	griffith	PROPN
biomedich-166	34	26	et	et	PROPN
biomedich-166	34	27	al	al	PROPN
biomedich-166	34	28	.	.	PROPN
biomedich-166	34	29	,	,	PUNCT
biomedich-166	34	30	2007	2007	NUM
biomedich-166	34	31	)	)	PUNCT
biomedich-166	34	32	.	.	PUNCT
biomedich-166	35	1	artemisinin	artemisinin	PROPN
biomedich-166	35	2	derivatives	derivative	NOUN
biomedich-166	35	3	are	be	AUX
biomedich-166	35	4	highly	highly	ADV
biomedich-166	35	5	potent	potent	ADJ
biomedich-166	35	6	with	with	ADP
biomedich-166	35	7	fast	fast	ADJ
biomedich-166	35	8	acting	act	VERB
biomedich-166	35	9	antiplasmodial	antiplasmodial	ADJ
biomedich-166	35	10	activity	activity	NOUN
biomedich-166	35	11	.	.	PUNCT
biomedich-166	36	1	however	however	ADV
biomedich-166	36	2	,	,	PUNCT
biomedich-166	36	3	due	due	ADP
biomedich-166	36	4	to	to	ADP
biomedich-166	36	5	short	short	ADJ
biomedich-166	36	6	half	half	ADJ
biomedich-166	36	7	-	-	PUNCT
biomedich-166	36	8	life	life	NOUN
biomedich-166	36	9	,	,	PUNCT
biomedich-166	36	10	and	and	CCONJ
biomedich-166	36	11	plasmodium	plasmodium	NOUN
biomedich-166	36	12	parasite	parasite	NOUN
biomedich-166	36	13	resistance	resistance	NOUN
biomedich-166	36	14	to	to	ADP
biomedich-166	36	15	artemisinin	artemisinin	NOUN
biomedich-166	36	16	derivatives	derivative	NOUN
biomedich-166	36	17	and	and	CCONJ
biomedich-166	36	18	older	old	ADJ
biomedich-166	36	19	antimalarial	antimalarial	ADJ
biomedich-166	36	20	drugs	drug	NOUN
biomedich-166	36	21	,	,	PUNCT
biomedich-166	36	22	artemisinin	artemisinin	PROPN
biomedich-166	36	23	derivatives	derivative	NOUN
biomedich-166	36	24	are	be	AUX
biomedich-166	36	25	often	often	ADV
biomedich-166	36	26	combined	combine	VERB
biomedich-166	36	27	with	with	ADP
biomedich-166	36	28	partner	partner	NOUN
biomedich-166	36	29	drugs	drug	NOUN
biomedich-166	36	30	with	with	ADP
biomedich-166	36	31	longer	long	ADJ
biomedich-166	36	32	half	half	ADJ
biomedich-166	36	33	-	-	PUNCT
biomedich-166	36	34	life	life	NOUN
biomedich-166	36	35	for	for	ADP
biomedich-166	36	36	fast	fast	ADJ
biomedich-166	36	37	clearance	clearance	NOUN
biomedich-166	36	38	of	of	ADP
biomedich-166	36	39	malaria	malaria	NOUN
biomedich-166	36	40	parasites	parasite	NOUN
biomedich-166	36	41	(	(	PUNCT
biomedich-166	36	42	nosten	nosten	VERB
biomedich-166	36	43	,	,	PUNCT
biomedich-166	36	44	2007	2007	NUM
biomedich-166	36	45	)	)	PUNCT
biomedich-166	36	46	.	.	PUNCT
biomedich-166	37	1	this	this	PRON
biomedich-166	37	2	led	lead	VERB
biomedich-166	37	3	to	to	ADP
biomedich-166	37	4	the	the	DET
biomedich-166	37	5	development	development	NOUN
biomedich-166	37	6	of	of	ADP
biomedich-166	37	7	https://doi.org/10.14421/biomedich.2021.102.135-140	https://doi.org/10.14421/biomedich.2021.102.135-140	PROPN
biomedich-166	37	8	136	136	NUM
biomedich-166	37	9	biology	biology	NOUN
biomedich-166	37	10	,	,	PUNCT
biomedich-166	37	11	medicine	medicine	NOUN
biomedich-166	37	12	,	,	PUNCT
biomedich-166	37	13	&	&	CCONJ
biomedich-166	37	14	natural	natural	ADJ
biomedich-166	37	15	product	product	NOUN
biomedich-166	37	16	chemistry	chemistry	NOUN
biomedich-166	37	17	10	10	NUM
biomedich-166	37	18	(	(	PUNCT
biomedich-166	37	19	2	2	NUM
biomedich-166	37	20	)	)	PUNCT
biomedich-166	37	21	,	,	PUNCT
biomedich-166	37	22	2021	2021	NUM
biomedich-166	37	23	:	:	PUNCT
biomedich-166	37	24	135	135	NUM
biomedich-166	37	25	-	-	SYM
biomedich-166	37	26	140	140	NUM
biomedich-166	37	27	artemisinin	artemisinin	NOUN
biomedich-166	37	28	-	-	PUNCT
biomedich-166	37	29	based	base	VERB
biomedich-166	37	30	combination	combination	NOUN
biomedich-166	37	31	therapies	therapy	NOUN
biomedich-166	37	32	(	(	PUNCT
biomedich-166	37	33	acts	act	NOUN
biomedich-166	37	34	)	)	PUNCT
biomedich-166	37	35	,	,	PUNCT
biomedich-166	37	36	which	which	PRON
biomedich-166	37	37	have	have	AUX
biomedich-166	37	38	become	become	VERB
biomedich-166	37	39	the	the	DET
biomedich-166	37	40	mainstay	mainstay	NOUN
biomedich-166	37	41	for	for	ADP
biomedich-166	37	42	the	the	DET
biomedich-166	37	43	treatment	treatment	NOUN
biomedich-166	37	44	of	of	ADP
biomedich-166	37	45	malaria	malaria	NOUN
biomedich-166	37	46	especially	especially	ADV
biomedich-166	37	47	in	in	ADP
biomedich-166	37	48	malaria	malaria	ADJ
biomedich-166	37	49	endemic	endemic	ADJ
biomedich-166	37	50	regions	region	NOUN
biomedich-166	37	51	(	(	PUNCT
biomedich-166	37	52	basco	basco	PROPN
biomedich-166	37	53	et	et	PROPN
biomedich-166	37	54	al	al	PROPN
biomedich-166	37	55	.	.	PROPN
biomedich-166	37	56	,	,	PUNCT
biomedich-166	37	57	2017	2017	NUM
biomedich-166	37	58	)	)	PUNCT
biomedich-166	37	59	.	.	PUNCT
biomedich-166	38	1	however	however	ADV
biomedich-166	38	2	,	,	PUNCT
biomedich-166	38	3	plasmodium	plasmodium	NOUN
biomedich-166	38	4	parasites	parasite	NOUN
biomedich-166	38	5	with	with	ADP
biomedich-166	38	6	decreased	decrease	VERB
biomedich-166	38	7	susceptibility	susceptibility	NOUN
biomedich-166	38	8	to	to	ADP
biomedich-166	38	9	acts	act	NOUN
biomedich-166	38	10	’	'	PUNCT
biomedich-166	38	11	have	have	AUX
biomedich-166	38	12	emerged	emerge	VERB
biomedich-166	38	13	due	due	ADJ
biomedich-166	38	14	to	to	ADP
biomedich-166	38	15	both	both	PRON
biomedich-166	38	16	decreased	decrease	VERB
biomedich-166	38	17	susceptibility	susceptibility	NOUN
biomedich-166	38	18	to	to	ADP
biomedich-166	38	19	artemisinins	artemisinin	NOUN
biomedich-166	38	20	and	and	CCONJ
biomedich-166	38	21	partner	partner	NOUN
biomedich-166	38	22	drugs	drug	NOUN
biomedich-166	38	23	(	(	PUNCT
biomedich-166	38	24	leang	leang	PROPN
biomedich-166	38	25	et	et	PROPN
biomedich-166	38	26	al	al	PROPN
biomedich-166	38	27	.	.	PROPN
biomedich-166	38	28	,	,	PUNCT
biomedich-166	38	29	2013	2013	NUM
biomedich-166	38	30	;	;	PUNCT
biomedich-166	38	31	sanders	sanders	PROPN
biomedich-166	38	32	et	et	PROPN
biomedich-166	38	33	al	al	PROPN
biomedich-166	38	34	.	.	PROPN
biomedich-166	38	35	,	,	PUNCT
biomedich-166	38	36	2014	2014	NUM
biomedich-166	38	37	)	)	PUNCT
biomedich-166	38	38	.	.	PUNCT
biomedich-166	39	1	also	also	ADV
biomedich-166	39	2	,	,	PUNCT
biomedich-166	39	3	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	39	4	-	-	PUNCT
biomedich-166	39	5	piperaquine	piperaquine	NOUN
biomedich-166	39	6	(	(	PUNCT
biomedich-166	39	7	d	d	NOUN
biomedich-166	39	8	-	-	PUNCT
biomedich-166	39	9	p	p	NOUN
biomedich-166	39	10	)	)	PUNCT
biomedich-166	39	11	,	,	PUNCT
biomedich-166	39	12	one	one	NUM
biomedich-166	39	13	of	of	ADP
biomedich-166	39	14	the	the	DET
biomedich-166	39	15	currently	currently	ADV
biomedich-166	39	16	used	use	VERB
biomedich-166	39	17	acts	act	NOUN
biomedich-166	39	18	,	,	PUNCT
biomedich-166	39	19	which	which	PRON
biomedich-166	39	20	is	be	AUX
biomedich-166	39	21	efficacious	efficacious	ADJ
biomedich-166	39	22	against	against	ADP
biomedich-166	39	23	malaria	malaria	NOUN
biomedich-166	39	24	(	(	PUNCT
biomedich-166	39	25	tayler	tayler	PROPN
biomedich-166	39	26	et	et	PROPN
biomedich-166	39	27	al	al	PROPN
biomedich-166	39	28	.	.	PROPN
biomedich-166	39	29	,	,	PUNCT
biomedich-166	39	30	2020	2020	NUM
biomedich-166	39	31	)	)	PUNCT
biomedich-166	39	32	and	and	CCONJ
biomedich-166	39	33	is	be	AUX
biomedich-166	39	34	being	be	AUX
biomedich-166	39	35	considered	consider	VERB
biomedich-166	39	36	for	for	ADP
biomedich-166	39	37	the	the	DET
biomedich-166	39	38	prevention	prevention	NOUN
biomedich-166	39	39	of	of	ADP
biomedich-166	39	40	malaria	malaria	NOUN
biomedich-166	39	41	in	in	ADP
biomedich-166	39	42	pregnancy	pregnancy	NOUN
biomedich-166	39	43	(	(	PUNCT
biomedich-166	39	44	kakuru	kakuru	ADV
biomedich-166	39	45	et	et	PROPN
biomedich-166	39	46	al	al	PROPN
biomedich-166	39	47	.	.	PROPN
biomedich-166	39	48	,	,	PUNCT
biomedich-166	39	49	2016	2016	NUM
biomedich-166	39	50	;	;	PUNCT
biomedich-166	39	51	desai	desai	PROPN
biomedich-166	39	52	et	et	PROPN
biomedich-166	39	53	al	al	PROPN
biomedich-166	39	54	.	.	PROPN
biomedich-166	39	55	,	,	PUNCT
biomedich-166	39	56	2016	2016	NUM
biomedich-166	39	57	)	)	PUNCT
biomedich-166	39	58	has	have	AUX
biomedich-166	39	59	experienced	experience	VERB
biomedich-166	39	60	plasmodium	plasmodium	NOUN
biomedich-166	39	61	resistance	resistance	NOUN
biomedich-166	39	62	in	in	ADP
biomedich-166	39	63	malaria	malaria	ADJ
biomedich-166	39	64	endemic	endemic	ADJ
biomedich-166	39	65	regions	region	NOUN
biomedich-166	39	66	.	.	PUNCT
biomedich-166	40	1	plasmodium	plasmodium	NOUN
biomedich-166	40	2	resistance	resistance	NOUN
biomedich-166	40	3	was	be	AUX
biomedich-166	40	4	attributed	attribute	VERB
biomedich-166	40	5	to	to	ADP
biomedich-166	40	6	decreased	decrease	VERB
biomedich-166	40	7	susceptibility	susceptibility	NOUN
biomedich-166	40	8	to	to	ADP
biomedich-166	40	9	both	both	CCONJ
biomedich-166	40	10	piperaquine	piperaquine	ADJ
biomedich-166	40	11	and	and	CCONJ
biomedich-166	40	12	dihyroartemisinin	dihyroartemisinin	NOUN
biomedich-166	40	13	(	(	PUNCT
biomedich-166	40	14	amaratunga	amaratunga	PROPN
biomedich-166	40	15	et	et	PROPN
biomedich-166	40	16	al	al	PROPN
biomedich-166	40	17	.	.	PROPN
biomedich-166	40	18	,	,	PUNCT
biomedich-166	40	19	2016	2016	NUM
biomedich-166	40	20	;	;	PUNCT
biomedich-166	40	21	amato	amato	PROPN
biomedich-166	40	22	et	et	PROPN
biomedich-166	40	23	al	al	PROPN
biomedich-166	40	24	.	.	PROPN
biomedich-166	40	25	,	,	PUNCT
biomedich-166	40	26	2017	2017	NUM
biomedich-166	40	27	)	)	PUNCT
biomedich-166	40	28	.	.	PUNCT
biomedich-166	41	1	hence	hence	ADV
biomedich-166	41	2	this	this	DET
biomedich-166	41	3	study	study	NOUN
biomedich-166	41	4	aimed	aim	VERB
biomedich-166	41	5	to	to	PART
biomedich-166	41	6	evaluate	evaluate	VERB
biomedich-166	41	7	if	if	SCONJ
biomedich-166	41	8	the	the	DET
biomedich-166	41	9	antiplasmodial	antiplasmodial	ADJ
biomedich-166	41	10	effect	effect	NOUN
biomedich-166	41	11	of	of	ADP
biomedich-166	41	12	d	d	X
biomedich-166	41	13	-	-	PUNCT
biomedich-166	41	14	p	p	NOUN
biomedich-166	41	15	can	can	AUX
biomedich-166	41	16	be	be	AUX
biomedich-166	41	17	augmented	augment	VERB
biomedich-166	41	18	by	by	ADP
biomedich-166	41	19	dx	dx	PROPN
biomedich-166	41	20	in	in	ADP
biomedich-166	41	21	mice	mouse	NOUN
biomedich-166	41	22	infected	infect	VERB
biomedich-166	41	23	with	with	ADP
biomedich-166	41	24	plasmodium	plasmodium	NOUN
biomedich-166	41	25	berghei	berghei	NOUN
biomedich-166	41	26	.	.	PUNCT
biomedich-166	42	1	materials	material	NOUN
biomedich-166	42	2	and	and	CCONJ
biomedich-166	42	3	methods	method	NOUN
biomedich-166	42	4	animals	animal	NOUN
biomedich-166	42	5	,	,	PUNCT
biomedich-166	42	6	drugs	drug	NOUN
biomedich-166	42	7	and	and	CCONJ
biomedich-166	42	8	parasites	parasite	NOUN
biomedich-166	42	9	swiss	swiss	VERB
biomedich-166	42	10	albino	albino	NOUN
biomedich-166	42	11	mice	mouse	NOUN
biomedich-166	42	12	of	of	ADP
biomedich-166	42	13	both	both	DET
biomedich-166	42	14	sexes	sex	NOUN
biomedich-166	42	15	(	(	PUNCT
biomedich-166	42	16	25	25	NUM
biomedich-166	42	17	-	-	SYM
biomedich-166	42	18	30	30	NUM
biomedich-166	42	19	g	g	NOUN
biomedich-166	42	20	)	)	PUNCT
biomedich-166	42	21	used	use	VERB
biomedich-166	42	22	for	for	ADP
biomedich-166	42	23	this	this	DET
biomedich-166	42	24	study	study	NOUN
biomedich-166	42	25	were	be	AUX
biomedich-166	42	26	sourced	source	VERB
biomedich-166	42	27	from	from	ADP
biomedich-166	42	28	the	the	DET
biomedich-166	42	29	animal	animal	NOUN
biomedich-166	42	30	husbandry	husbandry	NOUN
biomedich-166	42	31	of	of	ADP
biomedich-166	42	32	the	the	DET
biomedich-166	42	33	department	department	PROPN
biomedich-166	42	34	of	of	ADP
biomedich-166	42	35	pharmacology	pharmacology	NOUN
biomedich-166	42	36	,	,	PUNCT
biomedich-166	42	37	faculty	faculty	NOUN
biomedich-166	42	38	of	of	ADP
biomedich-166	42	39	basic	basic	ADJ
biomedich-166	42	40	clinical	clinical	ADJ
biomedich-166	42	41	sciences	science	NOUN
biomedich-166	42	42	,	,	PUNCT
biomedich-166	42	43	university	university	NOUN
biomedich-166	42	44	of	of	ADP
biomedich-166	42	45	port	port	NOUN
biomedich-166	42	46	harcourt	harcourt	PROPN
biomedich-166	42	47	,	,	PUNCT
biomedich-166	42	48	rivers	river	NOUN
biomedich-166	42	49	state	state	NOUN
biomedich-166	42	50	.	.	PUNCT
biomedich-166	43	1	the	the	DET
biomedich-166	43	2	mice	mouse	NOUN
biomedich-166	43	3	were	be	AUX
biomedich-166	43	4	housed	house	VERB
biomedich-166	43	5	in	in	ADP
biomedich-166	43	6	cages	cage	NOUN
biomedich-166	43	7	at	at	ADP
biomedich-166	43	8	temperature	temperature	NOUN
biomedich-166	43	9	20oc	20oc	PROPN
biomedich-166	43	10	with	with	ADP
biomedich-166	43	11	cycles	cycle	NOUN
biomedich-166	43	12	of	of	ADP
biomedich-166	43	13	12	12	NUM
biomedich-166	43	14	h	h	NOUN
biomedich-166	43	15	light/12	light/12	PROPN
biomedich-166	43	16	h	h	PROPN
biomedich-166	43	17	darkness	darkness	NOUN
biomedich-166	43	18	.	.	PUNCT
biomedich-166	44	1	the	the	DET
biomedich-166	44	2	mice	mouse	NOUN
biomedich-166	44	3	were	be	AUX
biomedich-166	44	4	acclimated	acclimate	VERB
biomedich-166	44	5	for	for	ADP
biomedich-166	44	6	2	2	NUM
biomedich-166	44	7	weeks	week	NOUN
biomedich-166	44	8	and	and	CCONJ
biomedich-166	44	9	fed	feed	VERB
biomedich-166	44	10	with	with	ADP
biomedich-166	44	11	food	food	NOUN
biomedich-166	44	12	pellets	pellet	NOUN
biomedich-166	44	13	and	and	CCONJ
biomedich-166	44	14	given	give	VERB
biomedich-166	44	15	water	water	NOUN
biomedich-166	44	16	ad	ad	NOUN
biomedich-166	44	17	libitum	libitum	X
biomedich-166	44	18	.	.	PUNCT
biomedich-166	45	1	cq	cq	PROPN
biomedich-166	45	2	was	be	AUX
biomedich-166	45	3	manufactured	manufacture	VERB
biomedich-166	45	4	by	by	ADP
biomedich-166	45	5	alben	alben	PROPN
biomedich-166	45	6	healthcare	healthcare	PROPN
biomedich-166	45	7	ind	ind	PROPN
biomedich-166	45	8	ltd	ltd	PROPN
biomedich-166	45	9	,	,	PUNCT
biomedich-166	45	10	d	d	X
biomedich-166	45	11	-	-	PUNCT
biomedich-166	45	12	p	p	NOUN
biomedich-166	45	13	was	be	AUX
biomedich-166	45	14	manufactured	manufacture	VERB
biomedich-166	45	15	by	by	ADP
biomedich-166	45	16	bliss	bliss	ADJ
biomedich-166	45	17	gvs	gvs	PROPN
biomedich-166	45	18	pharma	pharma	PROPN
biomedich-166	45	19	ltd	ltd	PROPN
biomedich-166	45	20	india	india	PROPN
biomedich-166	45	21	whereas	whereas	SCONJ
biomedich-166	45	22	dx	dx	PROPN
biomedich-166	45	23	was	be	AUX
biomedich-166	45	24	manufactured	manufacture	VERB
biomedich-166	45	25	by	by	ADP
biomedich-166	45	26	ranbaxy	ranbaxy	PROPN
biomedich-166	45	27	laboratories	laboratories	PROPN
biomedich-166	45	28	ltd	ltd	PROPN
biomedich-166	45	29	,	,	PUNCT
biomedich-166	45	30	india	india	PROPN
biomedich-166	45	31	.	.	PUNCT
biomedich-166	46	1	doses	dose	NOUN
biomedich-166	46	2	were	be	AUX
biomedich-166	46	3	selected	select	VERB
biomedich-166	46	4	based	base	VERB
biomedich-166	46	5	on	on	ADP
biomedich-166	46	6	previous	previous	ADJ
biomedich-166	46	7	studies	study	NOUN
biomedich-166	46	8	:	:	PUNCT
biomedich-166	46	9	cq	cq	PROPN
biomedich-166	46	10	(	(	PUNCT
biomedich-166	46	11	10mg	10mg	NOUN
biomedich-166	46	12	/	/	SYM
biomedich-166	46	13	kg	kg	NOUN
biomedich-166	46	14	)	)	PUNCT
biomedich-166	47	1	(	(	PUNCT
biomedich-166	47	2	somsak	somsak	NOUN
biomedich-166	47	3	et	et	PROPN
biomedich-166	47	4	al	al	PROPN
biomedich-166	47	5	.	.	PROPN
biomedich-166	47	6	,	,	PUNCT
biomedich-166	47	7	2018	2018	NUM
biomedich-166	47	8	)	)	PUNCT
biomedich-166	47	9	,	,	PUNCT
biomedich-166	47	10	dx	dx	PROPN
biomedich-166	47	11	(	(	PUNCT
biomedich-166	47	12	2.2	2.2	NUM
biomedich-166	47	13	mg	mg	PROPN
biomedich-166	47	14	/	/	SYM
biomedich-166	47	15	kg	kg	NOUN
biomedich-166	47	16	)	)	PUNCT
biomedich-166	47	17	(	(	PUNCT
biomedich-166	47	18	gaillard	gaillard	PROPN
biomedich-166	47	19	et	et	PROPN
biomedich-166	47	20	al	al	PROPN
biomedich-166	47	21	.	.	PROPN
biomedich-166	47	22	,	,	PUNCT
biomedich-166	47	23	2015	2015	NUM
biomedich-166	47	24	)	)	PUNCT
biomedich-166	47	25	and	and	CCONJ
biomedich-166	48	1	d	d	X
biomedich-166	48	2	-	-	PUNCT
biomedich-166	48	3	p	p	X
biomedich-166	48	4	(	(	PUNCT
biomedich-166	48	5	1.71/13.7	1.71/13.7	NUM
biomedich-166	48	6	mg	mg	PROPN
biomedich-166	48	7	/	/	SYM
biomedich-166	48	8	kg	kg	NOUN
biomedich-166	48	9	)	)	PUNCT
biomedich-166	48	10	(	(	PUNCT
biomedich-166	48	11	yavo	yavo	NOUN
biomedich-166	48	12	et	et	PROPN
biomedich-166	48	13	al	al	PROPN
biomedich-166	48	14	.	.	PROPN
biomedich-166	48	15	,	,	PUNCT
biomedich-166	48	16	2011	2011	NUM
biomedich-166	48	17	)	)	PUNCT
biomedich-166	48	18	.	.	PUNCT
biomedich-166	49	1	cq	cq	NOUN
biomedich-166	49	2	-	-	PUNCT
biomedich-166	49	3	sensitive	sensitive	ADJ
biomedich-166	49	4	plasmodium	plasmodium	NOUN
biomedich-166	49	5	berghei	berghei	NOUN
biomedich-166	49	6	(	(	PUNCT
biomedich-166	49	7	p.	p.	PROPN
biomedich-166	49	8	berghei	berghei	PROPN
biomedich-166	49	9	)	)	PUNCT
biomedich-166	49	10	(	(	PUNCT
biomedich-166	49	11	nk65	nk65	PROPN
biomedich-166	49	12	)	)	PUNCT
biomedich-166	49	13	was	be	AUX
biomedich-166	49	14	used	use	VERB
biomedich-166	49	15	.	.	PUNCT
biomedich-166	50	1	p.	p.	NOUN
biomedich-166	50	2	berghei	berghei	PROPN
biomedich-166	50	3	was	be	AUX
biomedich-166	50	4	obtained	obtain	VERB
biomedich-166	50	5	from	from	ADP
biomedich-166	50	6	nigerian	nigerian	PROPN
biomedich-166	50	7	institute	institute	PROPN
biomedich-166	50	8	of	of	ADP
biomedich-166	50	9	medical	medical	ADJ
biomedich-166	50	10	research	research	PROPN
biomedich-166	50	11	,	,	PUNCT
biomedich-166	50	12	yaba	yaba	PROPN
biomedich-166	50	13	,	,	PUNCT
biomedich-166	50	14	lagos	lago	NOUN
biomedich-166	50	15	.	.	PUNCT
biomedich-166	51	1	mice	mouse	NOUN
biomedich-166	51	2	used	use	VERB
biomedich-166	51	3	were	be	AUX
biomedich-166	51	4	inoculated	inoculate	VERB
biomedich-166	51	5	intraperitoneally	intraperitoneally	ADV
biomedich-166	51	6	(	(	PUNCT
biomedich-166	51	7	i.p	i.p	PROPN
biomedich-166	51	8	.	.	PROPN
biomedich-166	51	9	)	)	PUNCT
biomedich-166	51	10	with	with	ADP
biomedich-166	51	11	0.2	0.2	NUM
biomedich-166	51	12	 	 	SPACE
biomedich-166	51	13	ml	ml	NOUN
biomedich-166	51	14	of	of	ADP
biomedich-166	51	15	infected	infected	ADJ
biomedich-166	51	16	red	red	ADJ
biomedich-166	51	17	blood	blood	NOUN
biomedich-166	51	18	cells	cell	NOUN
biomedich-166	51	19	(	(	PUNCT
biomedich-166	51	20	rbcs	rbc	NOUN
biomedich-166	51	21	)	)	PUNCT
biomedich-166	51	22	containing	contain	VERB
biomedich-166	51	23	p.	p.	PROPN
biomedich-166	51	24	berghei	berghei	PROPN
biomedich-166	51	25	(	(	PUNCT
biomedich-166	51	26	1	1	NUM
biomedich-166	51	27	 	 	SPACE
biomedich-166	51	28	×	×	NOUN
biomedich-166	51	29	 	 	SPACE
biomedich-166	51	30	107	107	NUM
biomedich-166	51	31	)	)	PUNCT
biomedich-166	51	32	obtained	obtain	VERB
biomedich-166	51	33	from	from	ADP
biomedich-166	51	34	the	the	DET
biomedich-166	51	35	donor	donor	NOUN
biomedich-166	51	36	mice	mouse	NOUN
biomedich-166	51	37	.	.	PUNCT
biomedich-166	52	1	evaluation	evaluation	NOUN
biomedich-166	52	2	of	of	ADP
biomedich-166	52	3	antiplasmodial	antiplasmodial	ADJ
biomedich-166	52	4	activity	activity	NOUN
biomedich-166	52	5			NOUN
biomedich-166	52	6	evaluation	evaluation	NOUN
biomedich-166	52	7	of	of	ADP
biomedich-166	52	8	curative	curative	ADJ
biomedich-166	52	9	activity	activity	NOUN
biomedich-166	52	10	curative	curative	ADJ
biomedich-166	52	11	activity	activity	NOUN
biomedich-166	52	12	was	be	AUX
biomedich-166	52	13	performed	perform	VERB
biomedich-166	52	14	as	as	SCONJ
biomedich-166	52	15	reported	report	VERB
biomedich-166	52	16	by	by	ADP
biomedich-166	52	17	ryley	ryley	NOUN
biomedich-166	52	18	and	and	CCONJ
biomedich-166	52	19	peters	peters	PROPN
biomedich-166	52	20	(	(	PUNCT
biomedich-166	52	21	1970	1970	NUM
biomedich-166	52	22	)	)	PUNCT
biomedich-166	52	23	.	.	PUNCT
biomedich-166	53	1	twenty	twenty	NUM
biomedich-166	53	2	-	-	PUNCT
biomedich-166	53	3	five	five	NUM
biomedich-166	53	4	swiss	swiss	ADJ
biomedich-166	53	5	albino	albino	NOUN
biomedich-166	53	6	mice	mouse	NOUN
biomedich-166	53	7	were	be	AUX
biomedich-166	53	8	inoculated	inoculate	VERB
biomedich-166	53	9	i.p	i.p	PROPN
biomedich-166	53	10	with	with	ADP
biomedich-166	53	11	blood	blood	NOUN
biomedich-166	53	12	containing	contain	VERB
biomedich-166	53	13	1	1	NUM
biomedich-166	53	14	×	×	NOUN
biomedich-166	53	15	107	107	NUM
biomedich-166	53	16	.	.	PUNCT
biomedich-166	54	1	p.	p.	NOUN
biomedich-166	54	2	berghei	berghei	PROPN
biomedich-166	55	1	and	and	CCONJ
biomedich-166	56	1	grouped	group	VERB
biomedich-166	56	2	into	into	ADP
biomedich-166	56	3	5	5	NUM
biomedich-166	56	4	of	of	ADP
biomedich-166	56	5	5	5	NUM
biomedich-166	56	6	mice	mouse	NOUN
biomedich-166	56	7	each	each	PRON
biomedich-166	56	8	.	.	PUNCT
biomedich-166	57	1	the	the	DET
biomedich-166	57	2	first	first	ADJ
biomedich-166	57	3	two	two	NUM
biomedich-166	57	4	groups	group	NOUN
biomedich-166	57	5	,	,	PUNCT
biomedich-166	57	6	ai	ai	INTJ
biomedich-166	57	7	(	(	PUNCT
biomedich-166	57	8	negative	negative	ADJ
biomedich-166	57	9	control	control	NOUN
biomedich-166	57	10	)	)	PUNCT
biomedich-166	57	11	and	and	CCONJ
biomedich-166	57	12	a2	a2	PROPN
biomedich-166	57	13	(	(	PUNCT
biomedich-166	57	14	positive	positive	ADJ
biomedich-166	57	15	control	control	NOUN
biomedich-166	57	16	)	)	PUNCT
biomedich-166	57	17	were	be	AUX
biomedich-166	57	18	orally	orally	ADV
biomedich-166	57	19	treated	treat	VERB
biomedich-166	57	20	with	with	ADP
biomedich-166	57	21	normal	normal	ADJ
biomedich-166	57	22	saline	saline	NOUN
biomedich-166	57	23	(	(	PUNCT
biomedich-166	57	24	0.2ml	0.2ml	NUM
biomedich-166	57	25	)	)	PUNCT
biomedich-166	57	26	and	and	CCONJ
biomedich-166	57	27	cq	cq	PROPN
biomedich-166	57	28	(	(	PUNCT
biomedich-166	57	29	10mg	10mg	PROPN
biomedich-166	57	30	/	/	SYM
biomedich-166	57	31	kg	kg	NOUN
biomedich-166	57	32	)	)	PUNCT
biomedich-166	57	33	daily	daily	ADV
biomedich-166	57	34	for	for	ADP
biomedich-166	57	35	4	4	NUM
biomedich-166	57	36	days	day	NOUN
biomedich-166	57	37	,	,	PUNCT
biomedich-166	57	38	respectively	respectively	ADV
biomedich-166	57	39	.	.	PUNCT
biomedich-166	58	1	groups	group	NOUN
biomedich-166	58	2	a3	a3	NOUN
biomedich-166	58	3	-	-	PUNCT
biomedich-166	58	4	a5	a5	PROPN
biomedich-166	58	5	were	be	AUX
biomedich-166	58	6	orally	orally	ADV
biomedich-166	58	7	treated	treat	VERB
biomedich-166	58	8	with	with	ADP
biomedich-166	58	9	dx	dx	PROPN
biomedich-166	58	10	(	(	PUNCT
biomedich-166	58	11	2.2	2.2	NUM
biomedich-166	58	12	mg	mg	PROPN
biomedich-166	58	13	/	/	SYM
biomedich-166	58	14	kg	kg	PROPN
biomedich-166	58	15	)	)	PUNCT
biomedich-166	58	16	,	,	PUNCT
biomedich-166	58	17	d	d	X
biomedich-166	58	18	-	-	PUNCT
biomedich-166	58	19	p	p	X
biomedich-166	58	20	(	(	PUNCT
biomedich-166	58	21	1.71/13.7	1.71/13.7	NUM
biomedich-166	58	22	mg	mg	PROPN
biomedich-166	58	23	/	/	SYM
biomedich-166	58	24	kg	kg	NOUN
biomedich-166	58	25	)	)	PUNCT
biomedich-166	58	26	and	and	CCONJ
biomedich-166	58	27	d	d	X
biomedich-166	58	28	-	-	PUNCT
biomedich-166	58	29	p	p	NUM
biomedich-166	58	30	-	-	PUNCT
biomedich-166	58	31	dx	dx	NOUN
biomedich-166	58	32	daily	daily	ADV
biomedich-166	58	33	for	for	ADP
biomedich-166	58	34	4	4	NUM
biomedich-166	58	35	days	day	NOUN
biomedich-166	58	36	,	,	PUNCT
biomedich-166	58	37	respectively	respectively	ADV
biomedich-166	58	38	.	.	PUNCT
biomedich-166	59	1	on	on	ADP
biomedich-166	59	2	day	day	NOUN
biomedich-166	59	3	5	5	NUM
biomedich-166	59	4	,	,	PUNCT
biomedich-166	59	5	tail	tail	NOUN
biomedich-166	59	6	blood	blood	NOUN
biomedich-166	59	7	samples	sample	NOUN
biomedich-166	59	8	were	be	AUX
biomedich-166	59	9	collected	collect	VERB
biomedich-166	59	10	from	from	ADP
biomedich-166	59	11	the	the	DET
biomedich-166	59	12	mice	mouse	NOUN
biomedich-166	59	13	;	;	PUNCT
biomedich-166	59	14	thin	thin	ADJ
biomedich-166	59	15	blood	blood	NOUN
biomedich-166	59	16	films	film	NOUN
biomedich-166	59	17	were	be	AUX
biomedich-166	59	18	produced	produce	VERB
biomedich-166	59	19	on	on	ADP
biomedich-166	59	20	slides	slide	NOUN
biomedich-166	59	21	and	and	CCONJ
biomedich-166	59	22	stained	stain	VERB
biomedich-166	59	23	with	with	ADP
biomedich-166	59	24	giemsa	giemsa	NOUN
biomedich-166	59	25	stain	stain	NOUN
biomedich-166	59	26	and	and	CCONJ
biomedich-166	59	27	viewed	view	VERB
biomedich-166	59	28	with	with	ADP
biomedich-166	59	29	the	the	DET
biomedich-166	59	30	aid	aid	NOUN
biomedich-166	59	31	of	of	ADP
biomedich-166	59	32	a	a	DET
biomedich-166	59	33	microscope	microscope	NOUN
biomedich-166	59	34	.	.	PUNCT
biomedich-166	60	1	evaluations	evaluation	NOUN
biomedich-166	60	2	for	for	ADP
biomedich-166	60	3	percentage	percentage	NOUN
biomedich-166	60	4	parasitemia	parasitemia	NOUN
biomedich-166	60	5	and	and	CCONJ
biomedich-166	60	6	inhibitions	inhibition	NOUN
biomedich-166	60	7	were	be	AUX
biomedich-166	60	8	performed	perform	VERB
biomedich-166	60	9	using	use	VERB
biomedich-166	60	10	the	the	DET
biomedich-166	60	11	formula	formula	NOUN
biomedich-166	60	12	below	below	ADV
biomedich-166	60	13	.	.	PUNCT
biomedich-166	61	1	%	%	INTJ
biomedich-166	61	2	parasitemia	parasitemia	NOUN
biomedich-166	61	3	=	=	NOUN
biomedich-166	61	4	number	number	NOUN
biomedich-166	61	5	of	of	ADP
biomedich-166	61	6	parasitized	parasitize	VERB
biomedich-166	61	7	red	red	ADJ
biomedich-166	61	8	blood	blood	NOUN
biomedich-166	61	9	cells	cell	NOUN
biomedich-166	61	10	(	(	PUNCT
biomedich-166	61	11	rbcs	rbc	NOUN
biomedich-166	61	12	)	)	PUNCT
biomedich-166	61	13	×	×	NOUN
biomedich-166	61	14	100	100	NUM
biomedich-166	61	15	total	total	ADJ
biomedich-166	61	16	number	number	NOUN
biomedich-166	61	17	of	of	ADP
biomedich-166	61	18	rbcs	rbc	NOUN
biomedich-166	61	19	count	count	VERB
biomedich-166	61	20	%	%	NOUN
biomedich-166	61	21	inhibition	inhibition	NOUN
biomedich-166	61	22	=	=	PUNCT
biomedich-166	61	23	(	(	PUNCT
biomedich-166	61	24	%	%	INTJ
biomedich-166	61	25	parasitemia	parasitemia	NOUN
biomedich-166	61	26	of	of	ADP
biomedich-166	61	27	negative	negative	ADJ
biomedich-166	61	28	control	control	NOUN
biomedich-166	61	29	−	−	NOUN
biomedich-166	61	30	%	%	NOUN
biomedich-166	61	31	parasitemia	parasitemia	NOUN
biomedich-166	61	32	of	of	ADP
biomedich-166	61	33	treated	treat	VERB
biomedich-166	61	34	group	group	NOUN
biomedich-166	61	35	)	)	PUNCT
biomedich-166	61	36	×	×	NOUN
biomedich-166	61	37	100	100	NUM
biomedich-166	61	38	%	%	NOUN
biomedich-166	61	39	parasitemia	parasitemia	NOUN
biomedich-166	61	40	of	of	ADP
biomedich-166	61	41	negative	negative	ADJ
biomedich-166	61	42	control	control	NOUN
biomedich-166	61	43			NOUN
biomedich-166	61	44	evaluation	evaluation	NOUN
biomedich-166	61	45	of	of	ADP
biomedich-166	61	46	prophylactic	prophylactic	ADJ
biomedich-166	61	47	activity	activity	NOUN
biomedich-166	61	48	prophylactic	prophylactic	ADJ
biomedich-166	61	49	test	test	NOUN
biomedich-166	61	50	was	be	AUX
biomedich-166	61	51	performed	perform	VERB
biomedich-166	61	52	using	use	VERB
biomedich-166	61	53	an	an	DET
biomedich-166	61	54	established	establish	VERB
biomedich-166	61	55	method	method	NOUN
biomedich-166	61	56	described	describe	VERB
biomedich-166	61	57	by	by	ADP
biomedich-166	61	58	peters	peters	PROPN
biomedich-166	61	59	(	(	PUNCT
biomedich-166	61	60	1965	1965	NUM
biomedich-166	61	61	)	)	PUNCT
biomedich-166	61	62	.	.	PUNCT
biomedich-166	62	1	twenty	twenty	NUM
biomedich-166	62	2	-	-	PUNCT
biomedich-166	62	3	five	five	NUM
biomedich-166	62	4	swiss	swiss	ADJ
biomedich-166	62	5	albino	albino	NOUN
biomedich-166	62	6	mice	mouse	NOUN
biomedich-166	62	7	were	be	AUX
biomedich-166	62	8	assigned	assign	VERB
biomedich-166	62	9	to	to	ADP
biomedich-166	62	10	5	5	NUM
biomedich-166	62	11	groups	group	NOUN
biomedich-166	62	12	of	of	ADP
biomedich-166	62	13	5	5	NUM
biomedich-166	62	14	mice	mouse	NOUN
biomedich-166	62	15	each	each	PRON
biomedich-166	62	16	.	.	PUNCT
biomedich-166	63	1	group	group	PROPN
biomedich-166	63	2	bi	bi	PROPN
biomedich-166	63	3	served	serve	VERB
biomedich-166	63	4	as	as	ADP
biomedich-166	63	5	the	the	DET
biomedich-166	63	6	negative	negative	ADJ
biomedich-166	63	7	control	control	NOUN
biomedich-166	63	8	and	and	CCONJ
biomedich-166	63	9	group	group	NOUN
biomedich-166	63	10	b2	b2	NOUN
biomedich-166	63	11	served	serve	VERB
biomedich-166	63	12	as	as	ADP
biomedich-166	63	13	the	the	DET
biomedich-166	63	14	positive	positive	ADJ
biomedich-166	63	15	control	control	NOUN
biomedich-166	63	16	and	and	CCONJ
biomedich-166	63	17	were	be	AUX
biomedich-166	63	18	orally	orally	ADV
biomedich-166	63	19	treated	treat	VERB
biomedich-166	63	20	with	with	ADP
biomedich-166	63	21	normal	normal	ADJ
biomedich-166	63	22	saline	saline	NOUN
biomedich-166	63	23	(	(	PUNCT
biomedich-166	63	24	0.2ml	0.2ml	NUM
biomedich-166	63	25	)	)	PUNCT
biomedich-166	63	26	and	and	CCONJ
biomedich-166	63	27	cq	cq	PROPN
biomedich-166	63	28	(	(	PUNCT
biomedich-166	63	29	10mg	10mg	PROPN
biomedich-166	63	30	/	/	SYM
biomedich-166	63	31	kg	kg	NOUN
biomedich-166	63	32	)	)	PUNCT
biomedich-166	63	33	daily	daily	ADV
biomedich-166	63	34	for	for	ADP
biomedich-166	63	35	4	4	NUM
biomedich-166	63	36	days	day	NOUN
biomedich-166	63	37	,	,	PUNCT
biomedich-166	63	38	respectively	respectively	ADV
biomedich-166	63	39	.	.	PUNCT
biomedich-166	64	1	groups	group	NOUN
biomedich-166	64	2	b3	b3	PROPN
biomedich-166	64	3	-	-	PUNCT
biomedich-166	64	4	b5	b5	PROPN
biomedich-166	64	5	were	be	AUX
biomedich-166	64	6	orally	orally	ADV
biomedich-166	64	7	treated	treat	VERB
biomedich-166	64	8	with	with	ADP
biomedich-166	64	9	dx	dx	PROPN
biomedich-166	64	10	(	(	PUNCT
biomedich-166	64	11	2.2	2.2	NUM
biomedich-166	64	12	mg	mg	PROPN
biomedich-166	64	13	/	/	SYM
biomedich-166	64	14	kg	kg	PROPN
biomedich-166	64	15	)	)	PUNCT
biomedich-166	64	16	,	,	PUNCT
biomedich-166	64	17	d	d	X
biomedich-166	64	18	-	-	PUNCT
biomedich-166	64	19	p	p	X
biomedich-166	64	20	(	(	PUNCT
biomedich-166	64	21	1.71/13.7	1.71/13.7	NUM
biomedich-166	64	22	mg	mg	PROPN
biomedich-166	64	23	/	/	SYM
biomedich-166	64	24	kg	kg	NOUN
biomedich-166	64	25	)	)	PUNCT
biomedich-166	64	26	and	and	CCONJ
biomedich-166	64	27	d	d	X
biomedich-166	64	28	-	-	PUNCT
biomedich-166	64	29	pdx	pdx	PROPN
biomedich-166	64	30	daily	daily	NOUN
biomedich-166	64	31	for	for	ADP
biomedich-166	64	32	4	4	NUM
biomedich-166	64	33	days	day	NOUN
biomedich-166	64	34	,	,	PUNCT
biomedich-166	64	35	respectively	respectively	ADV
biomedich-166	64	36	.	.	PUNCT
biomedich-166	65	1	on	on	ADP
biomedich-166	65	2	day	day	NOUN
biomedich-166	65	3	5	5	NUM
biomedich-166	65	4	,	,	PUNCT
biomedich-166	65	5	the	the	DET
biomedich-166	65	6	mice	mouse	NOUN
biomedich-166	65	7	were	be	AUX
biomedich-166	65	8	inoculated	inoculate	VERB
biomedich-166	65	9	i.p	i.p	PROPN
biomedich-166	65	10	with	with	ADP
biomedich-166	65	11	0.2	0.2	NUM
biomedich-166	65	12	ml	ml	NOUN
biomedich-166	65	13	of	of	ADP
biomedich-166	65	14	infected	infected	ADJ
biomedich-166	65	15	blood	blood	NOUN
biomedich-166	65	16	containing	contain	VERB
biomedich-166	65	17	1x107p	1x107p	NUM
biomedich-166	65	18	.	.	PUNCT
biomedich-166	66	1	berghei	berghei	PROPN
biomedich-166	66	2	.	.	PUNCT
biomedich-166	67	1	after	after	ADP
biomedich-166	67	2	,	,	PUNCT
biomedich-166	67	3	3	3	NUM
biomedich-166	67	4	days	day	NOUN
biomedich-166	67	5	,	,	PUNCT
biomedich-166	67	6	tail	tail	NOUN
biomedich-166	67	7	blood	blood	NOUN
biomedich-166	67	8	samples	sample	NOUN
biomedich-166	67	9	were	be	AUX
biomedich-166	67	10	collected	collect	VERB
biomedich-166	67	11	and	and	CCONJ
biomedich-166	67	12	percentage	percentage	NOUN
biomedich-166	67	13	parasitemia	parasitemia	NOUN
biomedich-166	67	14	and	and	CCONJ
biomedich-166	67	15	inhibitions	inhibition	NOUN
biomedich-166	67	16	were	be	AUX
biomedich-166	67	17	calculated	calculate	VERB
biomedich-166	67	18	using	use	VERB
biomedich-166	67	19	the	the	DET
biomedich-166	67	20	formula	formula	NOUN
biomedich-166	67	21	above	above	ADV
biomedich-166	67	22	.	.	PUNCT
biomedich-166	68	1			X
biomedich-166	69	1	evaluation	evaluation	NOUN
biomedich-166	69	2	of	of	ADP
biomedich-166	69	3	suppressive	suppressive	ADJ
biomedich-166	69	4	activity	activity	NOUN
biomedich-166	69	5	suppressive	suppressive	ADJ
biomedich-166	69	6	test	test	NOUN
biomedich-166	69	7	was	be	AUX
biomedich-166	69	8	carried	carry	VERB
biomedich-166	69	9	out	out	ADP
biomedich-166	69	10	as	as	SCONJ
biomedich-166	69	11	described	describe	VERB
biomedich-166	69	12	by	by	ADP
biomedich-166	69	13	knight	knight	NOUN
biomedich-166	69	14	and	and	CCONJ
biomedich-166	69	15	peters	peters	PROPN
biomedich-166	69	16	(	(	PUNCT
biomedich-166	69	17	1980	1980	NUM
biomedich-166	69	18	)	)	PUNCT
biomedich-166	69	19	.	.	PUNCT
biomedich-166	70	1	twenty	twenty	NUM
biomedich-166	70	2	-	-	PUNCT
biomedich-166	70	3	five	five	NUM
biomedich-166	70	4	mice	mouse	NOUN
biomedich-166	70	5	were	be	AUX
biomedich-166	70	6	selected	select	VERB
biomedich-166	70	7	and	and	CCONJ
biomedich-166	70	8	inoculated	inoculate	VERB
biomedich-166	70	9	i.p	i.p	PROPN
biomedich-166	70	10	with	with	ADP
biomedich-166	70	11	blood	blood	NOUN
biomedich-166	70	12	containing	contain	VERB
biomedich-166	70	13	1x107	1x107	NUM
biomedich-166	70	14	p.	p.	NOUN
biomedich-166	70	15	berghei	berghei	NOUN
biomedich-166	70	16	.	.	PUNCT
biomedich-166	71	1	after	after	ADP
biomedich-166	71	2	3	3	NUM
biomedich-166	71	3	 	 	SPACE
biomedich-166	71	4	h	h	NOUN
biomedich-166	71	5	,	,	PUNCT
biomedich-166	71	6	the	the	DET
biomedich-166	71	7	mice	mouse	NOUN
biomedich-166	71	8	were	be	AUX
biomedich-166	71	9	randomized	randomize	VERB
biomedich-166	71	10	into	into	ADP
biomedich-166	71	11	5	5	NUM
biomedich-166	71	12	groups	group	NOUN
biomedich-166	71	13	of	of	ADP
biomedich-166	71	14	5	5	NUM
biomedich-166	71	15	mice	mouse	NOUN
biomedich-166	71	16	each	each	PRON
biomedich-166	71	17	.	.	PUNCT
biomedich-166	72	1	the	the	DET
biomedich-166	72	2	first	first	ADJ
biomedich-166	72	3	two	two	NUM
biomedich-166	72	4	groups	group	NOUN
biomedich-166	72	5	,	,	PUNCT
biomedich-166	72	6	ci	ci	PROPN
biomedich-166	72	7	(	(	PUNCT
biomedich-166	72	8	negative	negative	ADJ
biomedich-166	72	9	control	control	NOUN
biomedich-166	72	10	)	)	PUNCT
biomedich-166	72	11	and	and	CCONJ
biomedich-166	72	12	c2	c2	PROPN
biomedich-166	72	13	(	(	PUNCT
biomedich-166	72	14	positive	positive	ADJ
biomedich-166	72	15	control	control	NOUN
biomedich-166	72	16	)	)	PUNCT
biomedich-166	72	17	were	be	AUX
biomedich-166	72	18	orally	orally	ADV
biomedich-166	72	19	treated	treat	VERB
biomedich-166	72	20	with	with	ADP
biomedich-166	72	21	normal	normal	ADJ
biomedich-166	72	22	saline	saline	NOUN
biomedich-166	72	23	(	(	PUNCT
biomedich-166	72	24	0.2ml	0.2ml	NUM
biomedich-166	72	25	)	)	PUNCT
biomedich-166	72	26	and	and	CCONJ
biomedich-166	72	27	cq	cq	PROPN
biomedich-166	72	28	(	(	PUNCT
biomedich-166	72	29	10mg	10mg	PROPN
biomedich-166	72	30	/	/	SYM
biomedich-166	72	31	kg	kg	NOUN
biomedich-166	72	32	)	)	PUNCT
biomedich-166	72	33	daily	daily	ADV
biomedich-166	72	34	for	for	ADP
biomedich-166	72	35	4	4	NUM
biomedich-166	72	36	days	day	NOUN
biomedich-166	72	37	,	,	PUNCT
biomedich-166	72	38	respectively	respectively	ADV
biomedich-166	72	39	.	.	PUNCT
biomedich-166	73	1	groups	group	NOUN
biomedich-166	73	2	c3	c3	PROPN
biomedich-166	73	3	-	-	PUNCT
biomedich-166	73	4	c5	c5	PROPN
biomedich-166	73	5	were	be	AUX
biomedich-166	73	6	orally	orally	ADV
biomedich-166	73	7	treated	treat	VERB
biomedich-166	73	8	with	with	ADP
biomedich-166	73	9	dx	dx	PROPN
biomedich-166	73	10	(	(	PUNCT
biomedich-166	73	11	2.2	2.2	NUM
biomedich-166	73	12	mg	mg	PROPN
biomedich-166	73	13	/	/	SYM
biomedich-166	73	14	kg	kg	PROPN
biomedich-166	73	15	)	)	PUNCT
biomedich-166	73	16	,	,	PUNCT
biomedich-166	74	1	d	d	X
biomedich-166	74	2	-	-	PUNCT
biomedich-166	74	3	p	p	X
biomedich-166	74	4	(	(	PUNCT
biomedich-166	74	5	1.71/13.7	1.71/13.7	NUM
biomedich-166	74	6	mg	mg	PROPN
biomedich-166	74	7	/	/	SYM
biomedich-166	74	8	kg	kg	NOUN
biomedich-166	74	9	)	)	PUNCT
biomedich-166	74	10	and	and	CCONJ
biomedich-166	74	11	d	d	X
biomedich-166	74	12	-	-	PUNCT
biomedich-166	74	13	pdx	pdx	PROPN
biomedich-166	74	14	daily	daily	NOUN
biomedich-166	74	15	for	for	ADP
biomedich-166	74	16	4	4	NUM
biomedich-166	74	17	days	day	NOUN
biomedich-166	74	18	,	,	PUNCT
biomedich-166	74	19	respectively	respectively	ADV
biomedich-166	74	20	.	.	PUNCT
biomedich-166	75	1	on	on	ADP
biomedich-166	75	2	day	day	NOUN
biomedich-166	75	3	5	5	NUM
biomedich-166	75	4	,	,	PUNCT
biomedich-166	75	5	tail	tail	NOUN
biomedich-166	75	6	blood	blood	NOUN
biomedich-166	75	7	samples	sample	NOUN
biomedich-166	75	8	were	be	AUX
biomedich-166	75	9	collected	collect	VERB
biomedich-166	75	10	and	and	CCONJ
biomedich-166	75	11	evaluated	evaluate	VERB
biomedich-166	75	12	for	for	ADP
biomedich-166	75	13	percentage	percentage	NOUN
biomedich-166	75	14	parasitemia	parasitemia	NOUN
biomedich-166	75	15	and	and	CCONJ
biomedich-166	75	16	inhibitions	inhibition	NOUN
biomedich-166	75	17	using	use	VERB
biomedich-166	75	18	the	the	DET
biomedich-166	75	19	formula	formula	NOUN
biomedich-166	75	20	above	above	ADV
biomedich-166	75	21	.	.	PUNCT
biomedich-166	76	1	evaluation	evaluation	NOUN
biomedich-166	76	2	of	of	ADP
biomedich-166	76	3	biochemical	biochemical	ADJ
biomedich-166	76	4	parameters	parameter	NOUN
biomedich-166	76	5	blood	blood	NOUN
biomedich-166	76	6	samples	sample	NOUN
biomedich-166	76	7	were	be	AUX
biomedich-166	76	8	collected	collect	VERB
biomedich-166	76	9	from	from	ADP
biomedich-166	76	10	the	the	DET
biomedich-166	76	11	mice	mouse	NOUN
biomedich-166	76	12	used	use	VERB
biomedich-166	76	13	for	for	ADP
biomedich-166	76	14	the	the	DET
biomedich-166	76	15	curative	curative	ADJ
biomedich-166	76	16	test	test	NOUN
biomedich-166	76	17	and	and	CCONJ
biomedich-166	76	18	evaluated	evaluate	VERB
biomedich-166	76	19	for	for	ADP
biomedich-166	76	20	white	white	ADJ
biomedich-166	76	21	blood	blood	NOUN
biomedich-166	76	22	cells	cell	NOUN
biomedich-166	76	23	(	(	PUNCT
biomedich-166	76	24	wbcs	wbcs	PROPN
biomedich-166	76	25	)	)	PUNCT
biomedich-166	76	26	,	,	PUNCT
biomedich-166	76	27	hemoglobin	hemoglobin	NOUN
biomedich-166	76	28	(	(	PUNCT
biomedich-166	76	29	hb	hb	PROPN
biomedich-166	76	30	)	)	PUNCT
biomedich-166	76	31	,	,	PUNCT
biomedich-166	76	32	packed	pack	VERB
biomedich-166	76	33	cell	cell	NOUN
biomedich-166	76	34	volume	volume	NOUN
biomedich-166	76	35	(	(	PUNCT
biomedich-166	76	36	pcv	pcv	NOUN
biomedich-166	76	37	)	)	PUNCT
biomedich-166	76	38	,	,	PUNCT
biomedich-166	76	39	red	red	ADJ
biomedich-166	76	40	blood	blood	NOUN
biomedich-166	76	41	cells	cell	NOUN
biomedich-166	76	42	(	(	PUNCT
biomedich-166	76	43	rbcs	rbc	NOUN
biomedich-166	76	44	)	)	PUNCT
biomedich-166	76	45	,	,	PUNCT
biomedich-166	76	46	triglyceride	triglyceride	INTJ
biomedich-166	76	47	(	(	PUNCT
biomedich-166	76	48	tg	tg	INTJ
biomedich-166	76	49	)	)	PUNCT
biomedich-166	76	50	,	,	PUNCT
biomedich-166	76	51	total	total	ADJ
biomedich-166	76	52	cholesterol	cholesterol	NOUN
biomedich-166	76	53	(	(	PUNCT
biomedich-166	76	54	chol	chol	NOUN
biomedich-166	76	55	)	)	PUNCT
biomedich-166	76	56	,	,	PUNCT
biomedich-166	76	57	and	and	CCONJ
biomedich-166	76	58	high	high	ADJ
biomedich-166	76	59	-	-	PUNCT
biomedich-166	76	60	density	density	NOUN
biomedich-166	76	61	lipoprotein	lipoprotein	ADJ
biomedich-166	76	62	cholesterol	cholesterol	NOUN
biomedich-166	76	63	(	(	PUNCT
biomedich-166	76	64	hdl	hdl	NOUN
biomedich-166	76	65	-	-	PUNCT
biomedich-166	76	66	c	c	NOUN
biomedich-166	76	67	)	)	PUNCT
biomedich-166	76	68	using	use	VERB
biomedich-166	76	69	an	an	DET
biomedich-166	76	70	auto	auto	NOUN
biomedich-166	76	71	analyzer	analyzer	NOUN
biomedich-166	76	72	.	.	PUNCT
biomedich-166	77	1	georgewill	georgewill	PROPN
biomedich-166	77	2	&	&	CCONJ
biomedich-166	77	3	adikwu	adikwu	PROPN
biomedich-166	77	4	–	–	PUNCT
biomedich-166	77	5	repurposing	repurpose	VERB
biomedich-166	77	6	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	77	7	-	-	PUNCT
biomedich-166	77	8	piperaquine	piperaquine	NOUN
biomedich-166	77	9	-	-	PUNCT
biomedich-166	77	10	doxycycline	doxycycline	NOUN
biomedich-166	77	11	as	as	ADP
biomedich-166	77	12	…	…	PUNCT
biomedich-166	77	13	137	137	NUM
biomedich-166	77	14	statistical	statistical	ADJ
biomedich-166	77	15	analysis	analysis	NOUN
biomedich-166	77	16	results	result	NOUN
biomedich-166	77	17	as	as	ADP
biomedich-166	77	18	mean	mean	VERB
biomedich-166	77	19	±	±	NUM
biomedich-166	77	20	s	s	PROPN
biomedich-166	77	21	em	em	PRON
biomedich-166	77	22	(	(	PUNCT
biomedich-166	77	23	standard	standard	ADJ
biomedich-166	77	24	error	error	NOUN
biomedich-166	77	25	of	of	ADP
biomedich-166	77	26	mean	mean	NOUN
biomedich-166	77	27	)	)	PUNCT
biomedich-166	77	28	.	.	PUNCT
biomedich-166	77	29	data	datum	NOUN
biomedich-166	77	30	was	be	AUX
biomedich-166	77	31	analyzed	analyze	VERB
biomedich-166	77	32	using	use	VERB
biomedich-166	77	33	one	one	NUM
biomedich-166	77	34	-	-	PUNCT
biomedich-166	77	35	way	way	NOUN
biomedich-166	77	36	analysis	analysis	NOUN
biomedich-166	77	37	of	of	ADP
biomedich-166	77	38	variance	variance	NOUN
biomedich-166	77	39	(	(	PUNCT
biomedich-166	77	40	anova	anova	PROPN
biomedich-166	77	41	)	)	PUNCT
biomedich-166	77	42	and	and	CCONJ
biomedich-166	77	43	tukey	tukey	PROPN
biomedich-166	77	44	’s	’s	PART
biomedich-166	77	45	test	test	NOUN
biomedich-166	77	46	.	.	PUNCT
biomedich-166	78	1	differences	difference	NOUN
biomedich-166	78	2	between	between	ADP
biomedich-166	78	3	means	mean	NOUN
biomedich-166	78	4	were	be	AUX
biomedich-166	78	5	considered	consider	VERB
biomedich-166	78	6	significant	significant	ADJ
biomedich-166	78	7	at	at	ADP
biomedich-166	78	8	p	p	X
biomedich-166	78	9	 	 	SPACE
biomedich-166	78	10	<	<	X
biomedich-166	78	11	 	 	SPACE
biomedich-166	78	12	0.05	0.05	NUM
biomedich-166	78	13	,	,	PUNCT
biomedich-166	78	14	0.01	0.01	NUM
biomedich-166	78	15	and	and	CCONJ
biomedich-166	78	16	0.001	0.001	NUM
biomedich-166	78	17	,	,	PUNCT
biomedich-166	78	18	respectively	respectively	ADV
biomedich-166	78	19	.	.	PUNCT
biomedich-166	79	1	results	result	VERB
biomedich-166	79	2	curative	curative	ADJ
biomedich-166	79	3	activity	activity	NOUN
biomedich-166	79	4	treatment	treatment	NOUN
biomedich-166	79	5	with	with	ADP
biomedich-166	79	6	dx	dx	PROPN
biomedich-166	79	7	,	,	PUNCT
biomedich-166	79	8	d	d	PROPN
biomedich-166	79	9	-	-	PUNCT
biomedich-166	79	10	p	p	X
biomedich-166	79	11	,	,	PUNCT
biomedich-166	79	12	and	and	CCONJ
biomedich-166	79	13	d	d	X
biomedich-166	79	14	-	-	PUNCT
biomedich-166	79	15	p	p	NOUN
biomedich-166	79	16	-	-	PUNCT
biomedich-166	79	17	dx	dx	PROPN
biomedich-166	79	18	significantly	significantly	ADV
biomedich-166	79	19	decreased	decrease	VERB
biomedich-166	79	20	percentage	percentage	NOUN
biomedich-166	79	21	parasitemia	parasitemia	NOUN
biomedich-166	79	22	levels	level	NOUN
biomedich-166	79	23	at	at	ADP
biomedich-166	79	24	p<0.05	p<0.05	NOUN
biomedich-166	79	25	,	,	PUNCT
biomedich-166	79	26	p<0.01	p<0.01	PROPN
biomedich-166	79	27	and	and	CCONJ
biomedich-166	79	28	p<0.001	p<0.001	PROPN
biomedich-166	79	29	,	,	PUNCT
biomedich-166	79	30	respectively	respectively	ADV
biomedich-166	79	31	when	when	SCONJ
biomedich-166	79	32	compared	compare	VERB
biomedich-166	79	33	to	to	ADP
biomedich-166	79	34	the	the	DET
biomedich-166	79	35	negative	negative	ADJ
biomedich-166	79	36	control	control	NOUN
biomedich-166	79	37	(	(	PUNCT
biomedich-166	79	38	table	table	NOUN
biomedich-166	79	39	1	1	NUM
biomedich-166	79	40	)	)	PUNCT
biomedich-166	79	41	.	.	PUNCT
biomedich-166	80	1	the	the	DET
biomedich-166	80	2	observed	observed	ADJ
biomedich-166	80	3	parasitemia	parasitemia	NOUN
biomedich-166	80	4	inhibitions	inhibition	NOUN
biomedich-166	80	5	produced	produce	VERB
biomedich-166	80	6	by	by	ADP
biomedich-166	80	7	dx	dx	PROPN
biomedich-166	80	8	,	,	PUNCT
biomedich-166	80	9	d	d	PROPN
biomedich-166	80	10	-	-	PUNCT
biomedich-166	80	11	p	p	X
biomedich-166	80	12	,	,	PUNCT
biomedich-166	80	13	and	and	CCONJ
biomedich-166	80	14	d	d	X
biomedich-166	80	15	-	-	PUNCT
biomedich-166	80	16	p	p	NOUN
biomedich-166	80	17	-	-	PUNCT
biomedich-166	80	18	dx	dx	PROPN
biomedich-166	80	19	and	and	CCONJ
biomedich-166	80	20	cq	cq	PROPN
biomedich-166	80	21	were	be	AUX
biomedich-166	80	22	64.9	64.9	NUM
biomedich-166	80	23	%	%	NOUN
biomedich-166	80	24	,	,	PUNCT
biomedich-166	80	25	71.1	71.1	NUM
biomedich-166	80	26	%	%	NOUN
biomedich-166	80	27	,	,	PUNCT
biomedich-166	80	28	93.6	93.6	NUM
biomedich-166	80	29	%	%	NOUN
biomedich-166	80	30	,	,	PUNCT
biomedich-166	80	31	and	and	CCONJ
biomedich-166	80	32	75.0	75.0	NUM
biomedich-166	80	33	%	%	NOUN
biomedich-166	80	34	,	,	PUNCT
biomedich-166	80	35	respectively	respectively	ADV
biomedich-166	80	36	(	(	PUNCT
biomedich-166	80	37	table	table	NOUN
biomedich-166	80	38	2	2	NUM
biomedich-166	80	39	)	)	PUNCT
biomedich-166	80	40	.	.	PUNCT
biomedich-166	81	1	mst	mst	PROPN
biomedich-166	81	2	was	be	AUX
biomedich-166	81	3	significantly	significantly	ADV
biomedich-166	81	4	prolonged	prolong	VERB
biomedich-166	81	5	in	in	ADP
biomedich-166	81	6	mice	mouse	NOUN
biomedich-166	81	7	treated	treat	VERB
biomedich-166	81	8	with	with	ADP
biomedich-166	81	9	dx	dx	PROPN
biomedich-166	81	10	,	,	PUNCT
biomedich-166	81	11	d	d	PROPN
biomedich-166	81	12	-	-	PUNCT
biomedich-166	81	13	p	p	X
biomedich-166	81	14	,	,	PUNCT
biomedich-166	81	15	and	and	CCONJ
biomedich-166	81	16	d	d	X
biomedich-166	81	17	-	-	PUNCT
biomedich-166	81	18	p	p	X
biomedich-166	81	19	-	-	PUNCT
biomedich-166	81	20	dx	dx	NOUN
biomedich-166	81	21	at	at	ADP
biomedich-166	81	22	p<0.05	p<0.05	PROPN
biomedich-166	81	23	,	,	PUNCT
biomedich-166	81	24	p<0.01	p<0.01	PROPN
biomedich-166	81	25	,	,	PUNCT
biomedich-166	81	26	and	and	CCONJ
biomedich-166	81	27	p<0.001	p<0.001	PROPN
biomedich-166	81	28	,	,	PUNCT
biomedich-166	81	29	respectively	respectively	ADV
biomedich-166	81	30	when	when	SCONJ
biomedich-166	81	31	compared	compare	VERB
biomedich-166	81	32	to	to	ADP
biomedich-166	81	33	the	the	DET
biomedich-166	81	34	negative	negative	ADJ
biomedich-166	81	35	control	control	NOUN
biomedich-166	81	36	(	(	PUNCT
biomedich-166	81	37	table	table	NOUN
biomedich-166	81	38	1	1	NUM
biomedich-166	81	39	)	)	PUNCT
biomedich-166	81	40	.	.	PUNCT
biomedich-166	82	1	suppressive	suppressive	ADJ
biomedich-166	82	2	activity	activity	NOUN
biomedich-166	82	3	percentage	percentage	NOUN
biomedich-166	82	4	parasitemia	parasitemia	NOUN
biomedich-166	82	5	levels	level	NOUN
biomedich-166	82	6	were	be	AUX
biomedich-166	82	7	significantly	significantly	ADV
biomedich-166	82	8	decreased	decrease	VERB
biomedich-166	82	9	in	in	ADP
biomedich-166	82	10	mice	mouse	NOUN
biomedich-166	82	11	treated	treat	VERB
biomedich-166	82	12	with	with	ADP
biomedich-166	82	13	dx	dx	PROPN
biomedich-166	82	14	,	,	PUNCT
biomedich-166	82	15	d	d	PROPN
biomedich-166	82	16	-	-	PUNCT
biomedich-166	82	17	p	p	NOUN
biomedich-166	82	18	and	and	CCONJ
biomedich-166	82	19	d	d	NOUN
biomedich-166	82	20	-	-	ADJ
biomedich-166	82	21	p	p	X
biomedich-166	82	22	-	-	PUNCT
biomedich-166	82	23	dx	dx	NOUN
biomedich-166	82	24	at	at	ADP
biomedich-166	82	25	p<0.05	p<0.05	PROPN
biomedich-166	82	26	,	,	PUNCT
biomedich-166	82	27	p<0.01	p<0.01	PROPN
biomedich-166	82	28	,	,	PUNCT
biomedich-166	82	29	and	and	CCONJ
biomedich-166	82	30	p<0.001	p<0.001	PROPN
biomedich-166	82	31	,	,	PUNCT
biomedich-166	82	32	respectively	respectively	ADV
biomedich-166	82	33	when	when	SCONJ
biomedich-166	82	34	compared	compare	VERB
biomedich-166	82	35	to	to	ADP
biomedich-166	82	36	the	the	DET
biomedich-166	82	37	negative	negative	ADJ
biomedich-166	82	38	control	control	NOUN
biomedich-166	82	39	(	(	PUNCT
biomedich-166	82	40	table	table	NOUN
biomedich-166	82	41	2	2	NUM
biomedich-166	82	42	)	)	PUNCT
biomedich-166	82	43	.	.	PUNCT
biomedich-166	83	1	treatment	treatment	NOUN
biomedich-166	83	2	with	with	ADP
biomedich-166	83	3	dx	dx	PROPN
biomedich-166	83	4	,	,	PUNCT
biomedich-166	83	5	d	d	PROPN
biomedich-166	83	6	-	-	PUNCT
biomedich-166	83	7	p	p	NOUN
biomedich-166	83	8	and	and	CCONJ
biomedich-166	83	9	d	d	NOUN
biomedich-166	83	10	-	-	ADJ
biomedich-166	83	11	p	p	NOUN
biomedich-166	83	12	-	-	PUNCT
biomedich-166	83	13	dx	dx	PROPN
biomedich-166	83	14	produced	produce	VERB
biomedich-166	83	15	66.5	66.5	NUM
biomedich-166	83	16	%	%	NOUN
biomedich-166	83	17	,	,	PUNCT
biomedich-166	83	18	75.0	75.0	NUM
biomedich-166	83	19	%	%	NOUN
biomedich-166	83	20	,	,	PUNCT
biomedich-166	83	21	and	and	CCONJ
biomedich-166	83	22	95.1	95.1	NUM
biomedich-166	83	23	%	%	NOUN
biomedich-166	83	24	parasitemia	parasitemia	NOUN
biomedich-166	83	25	inhibitions	inhibition	NOUN
biomedich-166	83	26	,	,	PUNCT
biomedich-166	83	27	respectively	respectively	ADV
biomedich-166	83	28	whereas	whereas	SCONJ
biomedich-166	83	29	cq	cq	NOUN
biomedich-166	83	30	produced	produce	VERB
biomedich-166	83	31	81.9	81.9	NUM
biomedich-166	83	32	%	%	NOUN
biomedich-166	83	33	parasitemia	parasitemia	NOUN
biomedich-166	83	34	inhibition	inhibition	NOUN
biomedich-166	83	35	(	(	PUNCT
biomedich-166	83	36	table	table	NOUN
biomedich-166	83	37	2	2	NUM
biomedich-166	83	38	)	)	PUNCT
biomedich-166	83	39	.	.	PUNCT
biomedich-166	84	1	significant	significant	ADJ
biomedich-166	84	2	prolongation	prolongation	NOUN
biomedich-166	84	3	of	of	ADP
biomedich-166	84	4	mst	mst	PROPN
biomedich-166	84	5	in	in	ADP
biomedich-166	84	6	dx	dx	PROPN
biomedich-166	84	7	,	,	PUNCT
biomedich-166	84	8	d	d	PROPN
biomedich-166	84	9	-	-	PUNCT
biomedich-166	84	10	p	p	NOUN
biomedich-166	84	11	and	and	CCONJ
biomedich-166	84	12	d	d	PROPN
biomedich-166	84	13	-	-	PUNCT
biomedich-166	84	14	pdx	pdx	NOUN
biomedich-166	84	15	-	-	PUNCT
biomedich-166	84	16	treated	treat	VERB
biomedich-166	84	17	mice	mouse	NOUN
biomedich-166	84	18	occurred	occur	VERB
biomedich-166	84	19	at	at	ADP
biomedich-166	84	20	p<0.05	p<0.05	NOUN
biomedich-166	84	21	,	,	PUNCT
biomedich-166	84	22	p<0.01	p<0.01	PROPN
biomedich-166	84	23	and	and	CCONJ
biomedich-166	84	24	p<0.001	p<0.001	PROPN
biomedich-166	84	25	,	,	PUNCT
biomedich-166	84	26	respectively	respectively	ADV
biomedich-166	84	27	when	when	SCONJ
biomedich-166	84	28	compared	compare	VERB
biomedich-166	84	29	to	to	ADP
biomedich-166	84	30	negative	negative	ADJ
biomedich-166	84	31	control	control	NOUN
biomedich-166	84	32	(	(	PUNCT
biomedich-166	84	33	table	table	NOUN
biomedich-166	84	34	2	2	NUM
biomedich-166	84	35	)	)	PUNCT
biomedich-166	84	36	.	.	PUNCT
biomedich-166	85	1	prophylactic	prophylactic	ADJ
biomedich-166	85	2	activity	activity	NOUN
biomedich-166	85	3	the	the	DET
biomedich-166	85	4	prophylactic	prophylactic	ADJ
biomedich-166	85	5	test	test	NOUN
biomedich-166	85	6	showed	show	VERB
biomedich-166	85	7	significant	significant	ADJ
biomedich-166	85	8	decreases	decrease	NOUN
biomedich-166	85	9	in	in	ADP
biomedich-166	85	10	percentage	percentage	NOUN
biomedich-166	85	11	parasitemia	parasitemia	NOUN
biomedich-166	85	12	levels	level	NOUN
biomedich-166	85	13	in	in	ADP
biomedich-166	85	14	mice	mouse	NOUN
biomedich-166	85	15	treated	treat	VERB
biomedich-166	85	16	with	with	ADP
biomedich-166	85	17	dx	dx	PROPN
biomedich-166	85	18	(	(	PUNCT
biomedich-166	85	19	p<0.05	p<0.05	PROPN
biomedich-166	85	20	)	)	PUNCT
biomedich-166	85	21	,	,	PUNCT
biomedich-166	85	22	d	d	X
biomedich-166	85	23	-	-	PUNCT
biomedich-166	85	24	p	p	X
biomedich-166	85	25	(	(	PUNCT
biomedich-166	85	26	p<0.01	p<0.01	PROPN
biomedich-166	85	27	)	)	PUNCT
biomedich-166	85	28	and	and	CCONJ
biomedich-166	86	1	d	d	X
biomedich-166	86	2	-	-	PUNCT
biomedich-166	86	3	p	p	X
biomedich-166	86	4	-	-	PUNCT
biomedich-166	86	5	dx	dx	PROPN
biomedich-166	86	6	(	(	PUNCT
biomedich-166	86	7	p<0.001	p<0.001	PROPN
biomedich-166	86	8	)	)	PUNCT
biomedich-166	86	9	when	when	SCONJ
biomedich-166	86	10	compared	compare	VERB
biomedich-166	86	11	to	to	ADP
biomedich-166	86	12	the	the	DET
biomedich-166	86	13	negative	negative	ADJ
biomedich-166	86	14	control	control	NOUN
biomedich-166	86	15	(	(	PUNCT
biomedich-166	86	16	table	table	NOUN
biomedich-166	86	17	3	3	NUM
biomedich-166	86	18	)	)	PUNCT
biomedich-166	86	19	.	.	PUNCT
biomedich-166	87	1	the	the	DET
biomedich-166	87	2	percentage	percentage	NOUN
biomedich-166	87	3	parasitemia	parasitemia	NOUN
biomedich-166	87	4	inhibitions	inhibition	NOUN
biomedich-166	87	5	produced	produce	VERB
biomedich-166	87	6	by	by	ADP
biomedich-166	87	7	dx	dx	PROPN
biomedich-166	87	8	,	,	PUNCT
biomedich-166	87	9	d	d	PROPN
biomedich-166	87	10	-	-	PUNCT
biomedich-166	87	11	p	p	NOUN
biomedich-166	87	12	and	and	CCONJ
biomedich-166	87	13	d	d	NOUN
biomedich-166	87	14	-	-	ADJ
biomedich-166	87	15	p	p	NOUN
biomedich-166	87	16	-	-	PUNCT
biomedich-166	87	17	dx	dx	PROPN
biomedich-166	87	18	were	be	AUX
biomedich-166	87	19	65.1	65.1	NUM
biomedich-166	87	20	%	%	NOUN
biomedich-166	87	21	,	,	PUNCT
biomedich-166	87	22	86.8	86.8	NUM
biomedich-166	87	23	%	%	NOUN
biomedich-166	87	24	,	,	PUNCT
biomedich-166	87	25	and	and	CCONJ
biomedich-166	87	26	98.9	98.9	NUM
biomedich-166	87	27	%	%	NOUN
biomedich-166	87	28	,	,	PUNCT
biomedich-166	87	29	respectively	respectively	ADV
biomedich-166	87	30	while	while	SCONJ
biomedich-166	87	31	cq	cq	NOUN
biomedich-166	87	32	produced	produce	VERB
biomedich-166	87	33	an	an	DET
biomedich-166	87	34	inhibition	inhibition	NOUN
biomedich-166	87	35	of	of	ADP
biomedich-166	87	36	85.7	85.7	NUM
biomedich-166	87	37	%	%	NOUN
biomedich-166	87	38	(	(	PUNCT
biomedich-166	87	39	table	table	NOUN
biomedich-166	87	40	3	3	NUM
biomedich-166	87	41	)	)	PUNCT
biomedich-166	87	42	.	.	PUNCT
biomedich-166	88	1	mst	mst	PROPN
biomedich-166	88	2	was	be	AUX
biomedich-166	88	3	prolonged	prolong	VERB
biomedich-166	88	4	in	in	ADP
biomedich-166	88	5	dx	dx	PROPN
biomedich-166	88	6	,	,	PUNCT
biomedich-166	88	7	d	d	PROPN
biomedich-166	88	8	-	-	PUNCT
biomedich-166	88	9	p	p	X
biomedich-166	88	10	,	,	PUNCT
biomedich-166	88	11	and	and	CCONJ
biomedich-166	88	12	d	d	X
biomedich-166	88	13	-	-	PUNCT
biomedich-166	88	14	pdx	pdx	NOUN
biomedich-166	88	15	-	-	PUNCT
biomedich-166	88	16	treated	treat	VERB
biomedich-166	88	17	mice	mouse	NOUN
biomedich-166	88	18	.	.	PUNCT
biomedich-166	89	1	this	this	PRON
biomedich-166	89	2	occurred	occur	VERB
biomedich-166	89	3	at	at	ADP
biomedich-166	89	4	p<0.05	p<0.05	PROPN
biomedich-166	89	5	,	,	PUNCT
biomedich-166	89	6	p<0.01	p<0.01	PROPN
biomedich-166	89	7	,	,	PUNCT
biomedich-166	89	8	and	and	CCONJ
biomedich-166	89	9	p<0.001	p<0.001	PROPN
biomedich-166	89	10	,	,	PUNCT
biomedich-166	89	11	respectively	respectively	ADV
biomedich-166	89	12	when	when	SCONJ
biomedich-166	89	13	compared	compare	VERB
biomedich-166	89	14	to	to	ADP
biomedich-166	89	15	the	the	DET
biomedich-166	89	16	negative	negative	ADJ
biomedich-166	89	17	control	control	NOUN
biomedich-166	89	18	(	(	PUNCT
biomedich-166	89	19	table	table	NOUN
biomedich-166	89	20	3	3	NUM
biomedich-166	89	21	)	)	PUNCT
biomedich-166	89	22	.	.	PUNCT
biomedich-166	90	1	determination	determination	NOUN
biomedich-166	90	2	of	of	ADP
biomedich-166	90	3	mean	mean	ADJ
biomedich-166	90	4	survival	survival	NOUN
biomedich-166	90	5	time	time	NOUN
biomedich-166	90	6	the	the	DET
biomedich-166	90	7	mice	mouse	NOUN
biomedich-166	90	8	in	in	ADP
biomedich-166	90	9	the	the	DET
biomedich-166	90	10	control	control	NOUN
biomedich-166	90	11	and	and	CCONJ
biomedich-166	90	12	the	the	DET
biomedich-166	90	13	treated	treat	VERB
biomedich-166	90	14	groups	group	NOUN
biomedich-166	90	15	were	be	AUX
biomedich-166	90	16	observed	observe	VERB
biomedich-166	90	17	for	for	ADP
biomedich-166	90	18	mortality	mortality	NOUN
biomedich-166	90	19	and	and	CCONJ
biomedich-166	90	20	expressed	express	VERB
biomedich-166	90	21	in	in	ADP
biomedich-166	90	22	days	day	NOUN
biomedich-166	90	23	.	.	PUNCT
biomedich-166	91	1	mortality	mortality	NOUN
biomedich-166	91	2	represented	represent	VERB
biomedich-166	91	3	as	as	ADP
biomedich-166	91	4	mean	mean	ADJ
biomedich-166	91	5	survival	survival	NOUN
biomedich-166	91	6	time	time	NOUN
biomedich-166	91	7	(	(	PUNCT
biomedich-166	91	8	mst	mst	PROPN
biomedich-166	91	9	)	)	PUNCT
biomedich-166	91	10	was	be	AUX
biomedich-166	91	11	calculated	calculate	VERB
biomedich-166	91	12	using	use	VERB
biomedich-166	91	13	the	the	DET
biomedich-166	91	14	formula	formula	NOUN
biomedich-166	91	15	bellow	bellow	ADJ
biomedich-166	91	16	.	.	PUNCT
biomedich-166	92	1	𝑀𝑆𝑇	𝑀𝑆𝑇	NOUN
biomedich-166	92	2	=	=	PUNCT
biomedich-166	92	3	sum	sum	NOUN
biomedich-166	92	4	of	of	ADP
biomedich-166	92	5	survival	survival	NOUN
biomedich-166	92	6	time	time	NOUN
biomedich-166	92	7	of	of	ADP
biomedich-166	92	8	all	all	DET
biomedich-166	92	9	mice	mouse	NOUN
biomedich-166	92	10	in	in	ADP
biomedich-166	92	11	a	a	DET
biomedich-166	92	12	group	group	NOUN
biomedich-166	92	13	(	(	PUNCT
biomedich-166	92	14	days	day	NOUN
biomedich-166	92	15	)	)	PUNCT
biomedich-166	92	16	total	total	ADJ
biomedich-166	92	17	number	number	NOUN
biomedich-166	92	18	of	of	ADP
biomedich-166	92	19	mice	mouse	NOUN
biomedich-166	92	20	in	in	ADP
biomedich-166	92	21	that	that	DET
biomedich-166	92	22	group	group	NOUN
biomedich-166	92	23	hematological	hematological	NOUN
biomedich-166	92	24	and	and	CCONJ
biomedich-166	92	25	lipid	lipid	NOUN
biomedich-166	92	26	parameters	parameter	NOUN
biomedich-166	92	27	in	in	ADP
biomedich-166	92	28	p.	p.	PROPN
biomedich-166	92	29	berghei	berghei	PROPN
biomedich-166	92	30	-	-	PUNCT
biomedich-166	92	31	infected	infect	VERB
biomedich-166	92	32	mice	mouse	NOUN
biomedich-166	92	33	,	,	PUNCT
biomedich-166	92	34	tg	tg	PROPN
biomedich-166	92	35	,	,	PUNCT
biomedich-166	92	36	chol	chol	NOUN
biomedich-166	92	37	,	,	PUNCT
biomedich-166	92	38	ldl	ldl	NOUN
biomedich-166	92	39	-	-	PUNCT
biomedich-166	92	40	c	c	PROPN
biomedich-166	92	41	and	and	CCONJ
biomedich-166	92	42	wbcs	wbc	NOUN
biomedich-166	92	43	increased	increase	VERB
biomedich-166	92	44	whereas	whereas	SCONJ
biomedich-166	92	45	hb	hb	PROPN
biomedich-166	92	46	,	,	PUNCT
biomedich-166	92	47	pcv	pcv	NOUN
biomedich-166	92	48	,	,	PUNCT
biomedich-166	92	49	rbcs	rbc	NOUN
biomedich-166	92	50	and	and	CCONJ
biomedich-166	92	51	hdl	hdl	PROPN
biomedich-166	92	52	-	-	PUNCT
biomedich-166	92	53	c	c	PROPN
biomedich-166	92	54	decreased	decrease	VERB
biomedich-166	92	55	significantly	significantly	ADV
biomedich-166	92	56	(	(	PUNCT
biomedich-166	92	57	p<0.001	p<0.001	X
biomedich-166	92	58	)	)	PUNCT
biomedich-166	92	59	when	when	SCONJ
biomedich-166	92	60	compared	compare	VERB
biomedich-166	92	61	to	to	ADP
biomedich-166	92	62	the	the	DET
biomedich-166	92	63	normal	normal	ADJ
biomedich-166	92	64	control	control	NOUN
biomedich-166	92	65	(	(	PUNCT
biomedich-166	92	66	tables	table	NOUN
biomedich-166	92	67	4	4	NUM
biomedich-166	92	68	and	and	CCONJ
biomedich-166	92	69	5	5	NUM
biomedich-166	92	70	)	)	PUNCT
biomedich-166	92	71	.	.	PUNCT
biomedich-166	93	1	on	on	ADP
biomedich-166	93	2	the	the	DET
biomedich-166	93	3	other	other	ADJ
biomedich-166	93	4	hand	hand	NOUN
biomedich-166	93	5	,	,	PUNCT
biomedich-166	93	6	tg	tg	PROPN
biomedich-166	93	7	,	,	PUNCT
biomedich-166	93	8	chol	chol	NOUN
biomedich-166	93	9	,	,	PUNCT
biomedich-166	93	10	ldl	ldl	NOUN
biomedich-166	93	11	-	-	PUNCT
biomedich-166	93	12	c	c	PROPN
biomedich-166	93	13	wbcs	wbcs	NOUN
biomedich-166	93	14	levels	level	NOUN
biomedich-166	93	15	were	be	AUX
biomedich-166	93	16	decreased	decrease	VERB
biomedich-166	93	17	whereas	whereas	SCONJ
biomedich-166	93	18	hb	hb	PROPN
biomedich-166	93	19	,	,	PUNCT
biomedich-166	93	20	pcv	pcv	PROPN
biomedich-166	93	21	,	,	PUNCT
biomedich-166	93	22	rbc	rbc	PROPN
biomedich-166	93	23	and	and	CCONJ
biomedich-166	93	24	hdl	hdl	PROPN
biomedich-166	93	25	-	-	PUNCT
biomedich-166	93	26	c	c	PROPN
biomedich-166	93	27	levels	level	NOUN
biomedich-166	93	28	were	be	AUX
biomedich-166	93	29	increased	increase	VERB
biomedich-166	93	30	significantly	significantly	ADV
biomedich-166	93	31	in	in	ADP
biomedich-166	93	32	mice	mouse	NOUN
biomedich-166	93	33	treated	treat	VERB
biomedich-166	93	34	with	with	ADP
biomedich-166	93	35	dx	dx	PROPN
biomedich-166	93	36	,	,	PUNCT
biomedich-166	93	37	d	d	PROPN
biomedich-166	93	38	-	-	PUNCT
biomedich-166	93	39	p	p	X
biomedich-166	93	40	,	,	PUNCT
biomedich-166	93	41	and	and	CCONJ
biomedich-166	93	42	d	d	X
biomedich-166	93	43	-	-	PUNCT
biomedich-166	93	44	p	p	X
biomedich-166	93	45	-	-	PUNCT
biomedich-166	93	46	dx	dx	NOUN
biomedich-166	93	47	at	at	ADP
biomedich-166	93	48	p<0.05	p<0.05	PROPN
biomedich-166	93	49	,	,	PUNCT
biomedich-166	93	50	p<0.01	p<0.01	PROPN
biomedich-166	93	51	and	and	CCONJ
biomedich-166	93	52	p<0.001	p<0.001	PROPN
biomedich-166	93	53	,	,	PUNCT
biomedich-166	93	54	respectively	respectively	ADV
biomedich-166	93	55	when	when	SCONJ
biomedich-166	93	56	compared	compare	VERB
biomedich-166	93	57	to	to	ADP
biomedich-166	93	58	the	the	DET
biomedich-166	93	59	negative	negative	ADJ
biomedich-166	93	60	control	control	NOUN
biomedich-166	93	61	(	(	PUNCT
biomedich-166	93	62	tables	table	NOUN
biomedich-166	93	63	4	4	NUM
biomedich-166	93	64	and	and	CCONJ
biomedich-166	93	65	5	5	NUM
biomedich-166	93	66	)	)	PUNCT
biomedich-166	93	67	.	.	PUNCT
biomedich-166	94	1	table	table	NOUN
biomedich-166	94	2	1	1	NUM
biomedich-166	94	3	.	.	PUNCT
biomedich-166	95	1	curative	curative	ADJ
biomedich-166	95	2	antiplasmodial	antiplasmodial	ADJ
biomedich-166	95	3	effect	effect	NOUN
biomedich-166	95	4	of	of	ADP
biomedich-166	95	5	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	95	6	-	-	PUNCT
biomedich-166	95	7	piperaquine	piperaquine	NOUN
biomedich-166	95	8	-	-	PUNCT
biomedich-166	95	9	doxycycline	doxycycline	NOUN
biomedich-166	95	10	on	on	ADP
biomedich-166	95	11	mice	mouse	NOUN
biomedich-166	95	12	infected	infect	VERB
biomedich-166	95	13	with	with	ADP
biomedich-166	95	14	plasmodium	plasmodium	NOUN
biomedich-166	95	15	berghei	berghei	NOUN
biomedich-166	95	16	.	.	PUNCT
biomedich-166	96	1	treatment	treatment	NOUN
biomedich-166	96	2	%	%	NOUN
biomedich-166	96	3	parasitemia	parasitemia	NOUN
biomedich-166	96	4	%	%	NOUN
biomedich-166	96	5	inhibition	inhibition	NOUN
biomedich-166	96	6	mst	mst	PROPN
biomedich-166	96	7	(	(	PUNCT
biomedich-166	96	8	days	day	NOUN
biomedich-166	96	9	)	)	PUNCT
biomedich-166	96	10	pc	pc	NOUN
biomedich-166	96	11	35.10±3.00	35.10±3.00	NUM
biomedich-166	96	12	0.0	0.0	NUM
biomedich-166	96	13	9.22±0.18	9.22±0.18	NUM
biomedich-166	96	14	cq	cq	NOUN
biomedich-166	96	15	8.78±1.54a	8.78±1.54a	NOUN
biomedich-166	96	16	75.0	75.0	NUM
biomedich-166	96	17	27.62±2.39	27.62±2.39	NUM
biomedich-166	96	18	a.	a.	NOUN
biomedich-166	96	19	dx	dx	PROPN
biomedich-166	96	20	12.30±1.27b	12.30±1.27b	NUM
biomedich-166	96	21	64.9	64.9	NUM
biomedich-166	96	22	14.15±1.66b	14.15±1.66b	NUM
biomedich-166	96	23	d	d	X
biomedich-166	96	24	-	-	PUNCT
biomedich-166	96	25	p	p	X
biomedich-166	96	26	10.11±1.11a	10.11±1.11a	NUM
biomedich-166	96	27	71.1	71.1	NUM
biomedich-166	96	28	25.83±2.65	25.83±2.65	NUM
biomedich-166	96	29	a	a	DET
biomedich-166	96	30	d	d	ADJ
biomedich-166	96	31	-	-	PUNCT
biomedich-166	96	32	p	p	PROPN
biomedich-166	96	33	-	-	PUNCT
biomedich-166	96	34	dx	dx	NOUN
biomedich-166	96	35	2.25±0.15c	2.25±0.15c	NUM
biomedich-166	96	36	93.6	93.6	NUM
biomedich-166	96	37	36.96±3.48	36.96±3.48	PROPN
biomedich-166	96	38	c	c	PROPN
biomedich-166	96	39	data	datum	NOUN
biomedich-166	96	40	presented	present	VERB
biomedich-166	96	41	as	as	ADP
biomedich-166	96	42	±	±	NUM
biomedich-166	96	43	sem	sem	PROPN
biomedich-166	96	44	,	,	PUNCT
biomedich-166	96	45	n=	n=	ADJ
biomedich-166	96	46	5	5	NUM
biomedich-166	96	47	,	,	PUNCT
biomedich-166	96	48	pc	pc	NOUN
biomedich-166	96	49	:	:	PUNCT
biomedich-166	96	50	negative	negative	ADJ
biomedich-166	96	51	control	control	NOUN
biomedich-166	96	52	,	,	PUNCT
biomedich-166	96	53	cq	cq	PROPN
biomedich-166	96	54	:	:	PUNCT
biomedich-166	96	55	chloroquine	chloroquine	PROPN
biomedich-166	96	56	,	,	PUNCT
biomedich-166	96	57	dx	dx	PROPN
biomedich-166	96	58	:	:	PUNCT
biomedich-166	96	59	doxycycline	doxycycline	NOUN
biomedich-166	96	60	,	,	PUNCT
biomedich-166	96	61	d	d	X
biomedich-166	96	62	-	-	PUNCT
biomedich-166	96	63	p	p	X
biomedich-166	96	64	:	:	PUNCT
biomedich-166	96	65	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	96	66	-	-	PUNCT
biomedich-166	96	67	piperaquine	piperaquine	NOUN
biomedich-166	96	68	,	,	PUNCT
biomedich-166	96	69	mst	mst	PROPN
biomedich-166	96	70	:	:	PUNCT
biomedich-166	96	71	mean	mean	VERB
biomedich-166	96	72	survival	survival	NOUN
biomedich-166	96	73	time	time	NOUN
biomedich-166	96	74	.	.	PUNCT
biomedich-166	97	1	a	a	DET
biomedich-166	97	2	p<0.01	p<0.01	PROPN
biomedich-166	97	3	,	,	PUNCT
biomedich-166	97	4	b	b	X
biomedich-166	97	5	p<0.05	p<0.05	NOUN
biomedich-166	97	6	,	,	PUNCT
biomedich-166	97	7	c	c	NOUN
biomedich-166	97	8	p<0.001	p<0.001	X
biomedich-166	97	9	significant	significant	ADJ
biomedich-166	97	10	different	different	ADJ
biomedich-166	97	11	when	when	SCONJ
biomedich-166	97	12	compared	compare	VERB
biomedich-166	97	13	to	to	ADP
biomedich-166	97	14	pc	pc	NOUN
biomedich-166	97	15	,	,	PUNCT
biomedich-166	97	16	sem	sem	ADJ
biomedich-166	97	17	:	:	PUNCT
biomedich-166	97	18	standard	standard	ADJ
biomedich-166	97	19	error	error	NOUN
biomedich-166	97	20	mean	mean	NOUN
biomedich-166	97	21	.	.	PUNCT
biomedich-166	98	1	table	table	NOUN
biomedich-166	98	2	2	2	NUM
biomedich-166	98	3	.	.	PUNCT
biomedich-166	99	1	suppressive	suppressive	ADJ
biomedich-166	99	2	antiplasmodial	antiplasmodial	ADJ
biomedich-166	99	3	effect	effect	NOUN
biomedich-166	99	4	of	of	ADP
biomedich-166	99	5	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	99	6	-	-	PUNCT
biomedich-166	99	7	piperaquine	piperaquine	NOUN
biomedich-166	99	8	-	-	PUNCT
biomedich-166	99	9	doxycycline	doxycycline	NOUN
biomedich-166	99	10	on	on	ADP
biomedich-166	99	11	mice	mouse	NOUN
biomedich-166	99	12	infected	infect	VERB
biomedich-166	99	13	with	with	ADP
biomedich-166	99	14	plasmodium	plasmodium	NOUN
biomedich-166	99	15	berghei	berghei	NOUN
biomedich-166	99	16	.	.	PUNCT
biomedich-166	100	1	treatment	treatment	NOUN
biomedich-166	100	2	%	%	NOUN
biomedich-166	100	3	parasitemia	parasitemia	NOUN
biomedich-166	100	4	%	%	NOUN
biomedich-166	100	5	inhibition	inhibition	NOUN
biomedich-166	100	6	mst(days	mst(day	NOUN
biomedich-166	100	7	)	)	PUNCT
biomedich-166	100	8	pc	pc	NOUN
biomedich-166	100	9	17.60±2.54	17.60±2.54	NUM
biomedich-166	100	10	0.0	0.0	NUM
biomedich-166	100	11	9.40±0.33	9.40±0.33	NOUN
biomedich-166	100	12	cq	cq	NOUN
biomedich-166	100	13	3.19±0.01a	3.19±0.01a	NOUN
biomedich-166	100	14	81.9	81.9	NUM
biomedich-166	100	15	31.61±2.72a	31.61±2.72a	NUM
biomedich-166	100	16	dx	dx	PROPN
biomedich-166	100	17	5.90±0.08b	5.90±0.08b	NUM
biomedich-166	100	18	66.5	66.5	NUM
biomedich-166	100	19	20.47±2.67	20.47±2.67	NUM
biomedich-166	100	20	b	b	X
biomedich-166	100	21	d	d	X
biomedich-166	100	22	-	-	PUNCT
biomedich-166	100	23	p	p	ADJ
biomedich-166	100	24	4.40±0.09a	4.40±0.09a	NUM
biomedich-166	100	25	75.0	75.0	NUM
biomedich-166	100	26	29.73±3.11	29.73±3.11	NUM
biomedich-166	100	27	a	a	DET
biomedich-166	100	28	d	d	ADJ
biomedich-166	100	29	-	-	PUNCT
biomedich-166	100	30	p	p	NOUN
biomedich-166	100	31	-	-	PUNCT
biomedich-166	100	32	dx	dx	NOUN
biomedich-166	100	33	0.86±0.07c	0.86±0.07c	NUM
biomedich-166	100	34	95.1	95.1	NUM
biomedich-166	100	35	37.12±3,29	37.12±3,29	NUM
biomedich-166	100	36	c	c	PROPN
biomedich-166	100	37	data	datum	NOUN
biomedich-166	100	38	presented	present	VERB
biomedich-166	100	39	as	as	ADP
biomedich-166	100	40	±	±	NUM
biomedich-166	100	41	sem	sem	PROPN
biomedich-166	100	42	,	,	PUNCT
biomedich-166	100	43	n=	n=	ADJ
biomedich-166	100	44	5	5	NUM
biomedich-166	100	45	,	,	PUNCT
biomedich-166	100	46	pc	pc	NOUN
biomedich-166	100	47	:	:	PUNCT
biomedich-166	100	48	negative	negative	ADJ
biomedich-166	100	49	control	control	NOUN
biomedich-166	100	50	,	,	PUNCT
biomedich-166	100	51	cq	cq	PROPN
biomedich-166	100	52	:	:	PUNCT
biomedich-166	100	53	chloroquine	chloroquine	PROPN
biomedich-166	100	54	,	,	PUNCT
biomedich-166	100	55	dx	dx	PROPN
biomedich-166	100	56	:	:	PUNCT
biomedich-166	100	57	doxycycline	doxycycline	NOUN
biomedich-166	100	58	,	,	PUNCT
biomedich-166	100	59	d	d	X
biomedich-166	100	60	-	-	PUNCT
biomedich-166	100	61	p	p	X
biomedich-166	100	62	:	:	PUNCT
biomedich-166	100	63	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	100	64	-	-	PUNCT
biomedich-166	100	65	piperaquine	piperaquine	NOUN
biomedich-166	100	66	,	,	PUNCT
biomedich-166	100	67	mst	mst	PROPN
biomedich-166	100	68	:	:	PUNCT
biomedich-166	100	69	mean	mean	VERB
biomedich-166	100	70	survival	survival	NOUN
biomedich-166	100	71	time	time	NOUN
biomedich-166	100	72	.	.	PUNCT
biomedich-166	101	1	a	a	DET
biomedich-166	101	2	p<0.01	p<0.01	PROPN
biomedich-166	101	3	,	,	PUNCT
biomedich-166	101	4	b	b	X
biomedich-166	101	5	p<0.05	p<0.05	NOUN
biomedich-166	101	6	,	,	PUNCT
biomedich-166	101	7	c	c	NOUN
biomedich-166	101	8	p<0.001	p<0.001	X
biomedich-166	101	9	significant	significant	ADJ
biomedich-166	101	10	different	different	ADJ
biomedich-166	101	11	when	when	SCONJ
biomedich-166	101	12	compared	compare	VERB
biomedich-166	101	13	to	to	ADP
biomedich-166	101	14	pc	pc	NOUN
biomedich-166	101	15	,	,	PUNCT
biomedich-166	101	16	sem	sem	ADJ
biomedich-166	101	17	:	:	PUNCT
biomedich-166	101	18	standard	standard	ADJ
biomedich-166	101	19	error	error	NOUN
biomedich-166	101	20	mean	mean	NOUN
biomedich-166	101	21	.	.	PUNCT
biomedich-166	102	1	138	138	NUM
biomedich-166	102	2	biology	biology	NOUN
biomedich-166	102	3	,	,	PUNCT
biomedich-166	102	4	medicine	medicine	NOUN
biomedich-166	102	5	,	,	PUNCT
biomedich-166	102	6	&	&	CCONJ
biomedich-166	102	7	natural	natural	ADJ
biomedich-166	102	8	product	product	NOUN
biomedich-166	102	9	chemistry	chemistry	NOUN
biomedich-166	102	10	10	10	NUM
biomedich-166	102	11	(	(	PUNCT
biomedich-166	102	12	2	2	NUM
biomedich-166	102	13	)	)	PUNCT
biomedich-166	102	14	,	,	PUNCT
biomedich-166	102	15	2021	2021	NUM
biomedich-166	102	16	:	:	PUNCT
biomedich-166	102	17	135	135	NUM
biomedich-166	102	18	-	-	SYM
biomedich-166	102	19	140	140	NUM
biomedich-166	102	20	table	table	NOUN
biomedich-166	102	21	3	3	NUM
biomedich-166	102	22	.	.	PUNCT
biomedich-166	102	23	prophylactic	prophylactic	ADJ
biomedich-166	102	24	antiplasmodial	antiplasmodial	ADJ
biomedich-166	102	25	effect	effect	NOUN
biomedich-166	102	26	of	of	ADP
biomedich-166	102	27	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	102	28	-	-	PUNCT
biomedich-166	102	29	piperaquine	piperaquine	NOUN
biomedich-166	102	30	-	-	PUNCT
biomedich-166	102	31	doxycycline	doxycycline	NOUN
biomedich-166	102	32	on	on	ADP
biomedich-166	102	33	mice	mouse	NOUN
biomedich-166	102	34	infected	infect	VERB
biomedich-166	102	35	with	with	ADP
biomedich-166	102	36	plasmodium	plasmodium	NOUN
biomedich-166	102	37	berghei	berghei	NOUN
biomedich-166	102	38	.	.	PUNCT
biomedich-166	103	1	treatment	treatment	NOUN
biomedich-166	103	2	%	%	NOUN
biomedich-166	103	3	parasitemia	parasitemia	NOUN
biomedich-166	103	4	%	%	NOUN
biomedich-166	103	5	inhibition	inhibition	NOUN
biomedich-166	103	6	mst	mst	PROPN
biomedich-166	103	7	(	(	PUNCT
biomedich-166	103	8	days	day	NOUN
biomedich-166	103	9	)	)	PUNCT
biomedich-166	103	10	pc	pc	NOUN
biomedich-166	103	11	15.80±1.47	15.80±1.47	NUM
biomedich-166	103	12	0.0	0.0	NUM
biomedich-166	103	13	9.79±0.22	9.79±0.22	NOUN
biomedich-166	104	1	cq	cq	NOUN
biomedich-166	104	2	2.58±0.06a	2.58±0.06a	NUM
biomedich-166	104	3	85.7	85.7	NUM
biomedich-166	104	4	33.43±2.53	33.43±2.53	NUM
biomedich-166	104	5	a	a	DET
biomedich-166	104	6	dx	dx	PROPN
biomedich-166	104	7	5.51±0.07b	5.51±0.07b	NUM
biomedich-166	104	8	65.1	65.1	NUM
biomedich-166	104	9	22.75±3.57	22.75±3.57	NUM
biomedich-166	104	10	b	b	X
biomedich-166	104	11	d	d	X
biomedich-166	104	12	-	-	PUNCT
biomedich-166	104	13	p	p	NOUN
biomedich-166	104	14	3.03±0.04a	3.03±0.04a	ADP
biomedich-166	104	15	86.8	86.8	NUM
biomedich-166	104	16	30.91±2.89	30.91±2.89	NUM
biomedich-166	104	17	a	a	DET
biomedich-166	104	18	d	d	ADJ
biomedich-166	104	19	-	-	PUNCT
biomedich-166	104	20	p	p	NOUN
biomedich-166	104	21	-	-	PUNCT
biomedich-166	104	22	dx	dx	NOUN
biomedich-166	104	23	0.17±0.08c	0.17±0.08c	NUM
biomedich-166	104	24	98.9	98.9	NUM
biomedich-166	104	25	38.02±3.86	38.02±3.86	PROPN
biomedich-166	104	26	c	c	PROPN
biomedich-166	104	27	data	datum	NOUN
biomedich-166	104	28	presented	present	VERB
biomedich-166	104	29	as	as	ADP
biomedich-166	104	30	±	±	NUM
biomedich-166	104	31	sem	sem	PROPN
biomedich-166	104	32	,	,	PUNCT
biomedich-166	104	33	n=	n=	ADJ
biomedich-166	104	34	5	5	NUM
biomedich-166	104	35	,	,	PUNCT
biomedich-166	104	36	pc	pc	NOUN
biomedich-166	104	37	:	:	PUNCT
biomedich-166	104	38	negative	negative	ADJ
biomedich-166	104	39	control	control	NOUN
biomedich-166	104	40	,	,	PUNCT
biomedich-166	104	41	cq	cq	PROPN
biomedich-166	104	42	:	:	PUNCT
biomedich-166	104	43	chloroquine	chloroquine	PROPN
biomedich-166	104	44	,	,	PUNCT
biomedich-166	104	45	dx	dx	PROPN
biomedich-166	104	46	:	:	PUNCT
biomedich-166	104	47	doxycycline	doxycycline	NOUN
biomedich-166	104	48	,	,	PUNCT
biomedich-166	104	49	d	d	X
biomedich-166	104	50	-	-	PUNCT
biomedich-166	104	51	p	p	X
biomedich-166	104	52	:	:	PUNCT
biomedich-166	104	53	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	104	54	-	-	PUNCT
biomedich-166	104	55	piperaquine	piperaquine	NOUN
biomedich-166	104	56	,	,	PUNCT
biomedich-166	104	57	mst	mst	PROPN
biomedich-166	104	58	:	:	PUNCT
biomedich-166	104	59	mean	mean	VERB
biomedich-166	104	60	survival	survival	NOUN
biomedich-166	104	61	time	time	NOUN
biomedich-166	104	62	a	a	DET
biomedich-166	104	63	p<0.01	p<0.01	PROPN
biomedich-166	104	64	,	,	PUNCT
biomedich-166	104	65	b	b	X
biomedich-166	104	66	p<0.05	p<0.05	NOUN
biomedich-166	104	67	,	,	PUNCT
biomedich-166	104	68	c	c	NOUN
biomedich-166	104	69	p<0.001	p<0.001	X
biomedich-166	104	70	significant	significant	ADJ
biomedich-166	104	71	different	different	ADJ
biomedich-166	104	72	when	when	SCONJ
biomedich-166	104	73	compared	compare	VERB
biomedich-166	104	74	to	to	ADP
biomedich-166	104	75	pc	pc	NOUN
biomedich-166	104	76	,	,	PUNCT
biomedich-166	104	77	sem	sem	ADJ
biomedich-166	104	78	:	:	PUNCT
biomedich-166	104	79	standard	standard	ADJ
biomedich-166	104	80	error	error	NOUN
biomedich-166	104	81	mean	mean	NOUN
biomedich-166	104	82	.	.	PUNCT
biomedich-166	105	1	table	table	NOUN
biomedich-166	105	2	4	4	NUM
biomedich-166	105	3	.	.	PUNCT
biomedich-166	105	4	effect	effect	NOUN
biomedich-166	105	5	of	of	ADP
biomedich-166	105	6	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	105	7	-	-	PUNCT
biomedich-166	105	8	piperaquine	piperaquine	NOUN
biomedich-166	105	9	-	-	PUNCT
biomedich-166	105	10	doxycycline	doxycycline	NOUN
biomedich-166	105	11	on	on	ADP
biomedich-166	105	12	hematologic	hematologic	NOUN
biomedich-166	105	13	parameters	parameter	NOUN
biomedich-166	105	14	of	of	ADP
biomedich-166	105	15	mice	mouse	NOUN
biomedich-166	105	16	infected	infect	VERB
biomedich-166	105	17	plasmodium	plasmodium	NOUN
biomedich-166	105	18	berghei	berghei	NOUN
biomedich-166	105	19	.	.	PUNCT
biomedich-166	106	1	treatment	treatment	NOUN
biomedich-166	106	2	rbc	rbc	PROPN
biomedich-166	106	3	(	(	PUNCT
biomedich-166	106	4	x106	x106	PROPN
biomedich-166	106	5	)	)	PUNCT
biomedich-166	106	6	wbc	wbc	PROPN
biomedich-166	106	7	(	(	PUNCT
biomedich-166	106	8	cells	cell	NOUN
biomedich-166	106	9	/	/	SYM
biomedich-166	106	10	l	l	NOUN
biomedich-166	106	11	)	)	PUNCT
biomedich-166	106	12	pcv	pcv	NOUN
biomedich-166	106	13	(	(	PUNCT
biomedich-166	106	14	%	%	INTJ
biomedich-166	106	15	)	)	PUNCT
biomedich-166	106	16	hb	hb	PROPN
biomedich-166	106	17	(	(	PUNCT
biomedich-166	106	18	g	g	PROPN
biomedich-166	106	19	/	/	SYM
biomedich-166	106	20	dl	dl	PROPN
biomedich-166	106	21	)	)	PUNCT
biomedich-166	106	22	nc	nc	PROPN
biomedich-166	107	1	6.83±0.33	6.83±0.33	PROPN
biomedich-166	107	2	7.55±0.09	7.55±0.09	PROPN
biomedich-166	107	3	60.91±5.91	60.91±5.91	NUM
biomedich-166	107	4	16.93±1.35	16.93±1.35	NUM
biomedich-166	107	5	pc	pc	NOUN
biomedich-166	107	6	3.21±0.43a	3.21±0.43a	NUM
biomedich-166	107	7	15.71±1.55a	15.71±1.55a	NUM
biomedich-166	107	8	26.72±3.45a	26.72±3.45a	NUM
biomedich-166	107	9	6.01±0.17a	6.01±0.17a	NUM
biomedich-166	107	10	cq	cq	NOUN
biomedich-166	107	11	5.44±0.28b	5.44±0.28b	NOUN
biomedich-166	107	12	9.44±0.19b	9.44±0.19b	NUM
biomedich-166	107	13	44.21±4.33b	44.21±4.33b	NUM
biomedich-166	107	14	13.45±1.38b	13.45±1.38b	NUM
biomedich-166	107	15	dx	dx	PROPN
biomedich-166	107	16	4.37±0.27c	4.37±0.27c	NUM
biomedich-166	108	1	11.00±0.37c	11.00±0.37c	NUM
biomedich-166	108	2	31.94±3.47c	31.94±3.47c	NUM
biomedich-166	109	1	10.73±0.81c	10.73±0.81c	NUM
biomedich-166	110	1	d	d	NOUN
biomedich-166	110	2	-	-	PUNCT
biomedich-166	110	3	p	p	ADJ
biomedich-166	110	4	5.40±0.11b	5.40±0.11b	NUM
biomedich-166	110	5	9.57±0.16b	9.57±0.16b	NOUN
biomedich-166	110	6	42.62±3.67b	42.62±3.67b	NOUN
biomedich-166	110	7	13.07±1.11b	13.07±1.11b	NUM
biomedich-166	110	8	d	d	X
biomedich-166	110	9	-	-	PUNCT
biomedich-166	110	10	p	p	NOUN
biomedich-166	110	11	-	-	PUNCT
biomedich-166	110	12	dx	dx	NOUN
biomedich-166	110	13	6.61±0.32d	6.61±0.32d	NUM
biomedich-166	110	14	7.25±0.01d	7.25±0.01d	NUM
biomedich-166	110	15	55.9±4.41d	55.9±4.41d	NUM
biomedich-166	110	16	16.72±1.37d	16.72±1.37d	NUM
biomedich-166	110	17	data	datum	NOUN
biomedich-166	110	18	presented	present	VERB
biomedich-166	110	19	as	as	ADP
biomedich-166	110	20	±	±	NUM
biomedich-166	110	21	sem	sem	PROPN
biomedich-166	110	22	,	,	PUNCT
biomedich-166	110	23	n=	n=	ADJ
biomedich-166	110	24	5	5	NUM
biomedich-166	110	25	,	,	PUNCT
biomedich-166	110	26	nc	nc	ADJ
biomedich-166	110	27	:	:	PUNCT
biomedich-166	110	28	normal	normal	ADJ
biomedich-166	110	29	control	control	NOUN
biomedich-166	110	30	,	,	PUNCT
biomedich-166	110	31	pc	pc	NOUN
biomedich-166	110	32	:	:	PUNCT
biomedich-166	110	33	negative	negative	ADJ
biomedich-166	110	34	control	control	NOUN
biomedich-166	110	35	,	,	PUNCT
biomedich-166	110	36	cq	cq	PROPN
biomedich-166	110	37	:	:	PUNCT
biomedich-166	110	38	chloroquine	chloroquine	PROPN
biomedich-166	110	39	,	,	PUNCT
biomedich-166	110	40	dx	dx	PROPN
biomedich-166	110	41	:	:	PUNCT
biomedich-166	110	42	doxycycline	doxycycline	NOUN
biomedich-166	110	43	,	,	PUNCT
biomedich-166	110	44	d	d	X
biomedich-166	110	45	-	-	PUNCT
biomedich-166	110	46	p	p	X
biomedich-166	110	47	:	:	PUNCT
biomedich-166	110	48	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	110	49	-	-	PUNCT
biomedich-166	110	50	piperaquine	piperaquine	NOUN
biomedich-166	110	51	,	,	PUNCT
biomedich-166	110	52	mst	mst	PROPN
biomedich-166	110	53	:	:	PUNCT
biomedich-166	110	54	mean	mean	VERB
biomedich-166	110	55	survival	survival	PROPN
biomedich-166	110	56	time	time	NOUN
biomedich-166	110	57	,	,	PUNCT
biomedich-166	110	58	rbcs	rbc	NOUN
biomedich-166	110	59	:	:	PUNCT
biomedich-166	110	60	red	red	ADJ
biomedich-166	110	61	blood	blood	NOUN
biomedich-166	110	62	cell	cell	NOUN
biomedich-166	110	63	,	,	PUNCT
biomedich-166	110	64	wbcs	wbc	NOUN
biomedich-166	110	65	:	:	PUNCT
biomedich-166	110	66	white	white	ADJ
biomedich-166	110	67	blood	blood	NOUN
biomedich-166	110	68	cell	cell	NOUN
biomedich-166	110	69	,	,	PUNCT
biomedich-166	110	70	pcv	pcv	NOUN
biomedich-166	110	71	:	:	PUNCT
biomedich-166	110	72	packed	pack	VERB
biomedich-166	110	73	cell	cell	NOUN
biomedich-166	110	74	volume	volume	NOUN
biomedich-166	110	75	,	,	PUNCT
biomedich-166	110	76	hb	hb	PROPN
biomedich-166	110	77	:	:	PUNCT
biomedich-166	110	78	haemoglobin	haemoglobin	PROPN
biomedich-166	110	79	.	.	PUNCT
biomedich-166	111	1	a	a	DET
biomedich-166	111	2	p<0.001	p<0.001	ADJ
biomedich-166	111	3	significant	significant	ADJ
biomedich-166	111	4	difference	difference	NOUN
biomedich-166	111	5	when	when	SCONJ
biomedich-166	111	6	compared	compare	VERB
biomedich-166	111	7	to	to	ADP
biomedich-166	111	8	nc	nc	PROPN
biomedich-166	111	9	,	,	PUNCT
biomedich-166	111	10	b	b	PROPN
biomedich-166	111	11	p<0.01	p<0.01	PROPN
biomedich-166	111	12	,	,	PUNCT
biomedich-166	111	13	c	c	NOUN
biomedich-166	111	14	p<0.05	p<0.05	NOUN
biomedich-166	111	15	,	,	PUNCT
biomedich-166	111	16	d	d	NOUN
biomedich-166	111	17	p<0.001	p<0.001	X
biomedich-166	111	18	significant	significant	ADJ
biomedich-166	111	19	difference	difference	NOUN
biomedich-166	111	20	when	when	SCONJ
biomedich-166	111	21	compared	compare	VERB
biomedich-166	111	22	to	to	ADP
biomedich-166	111	23	pc	pc	NOUN
biomedich-166	111	24	,	,	PUNCT
biomedich-166	111	25	sem	sem	ADJ
biomedich-166	111	26	:	:	PUNCT
biomedich-166	111	27	standard	standard	ADJ
biomedich-166	111	28	error	error	NOUN
biomedich-166	111	29	mean	mean	NOUN
biomedich-166	111	30	.	.	PUNCT
biomedich-166	112	1	table	table	NOUN
biomedich-166	112	2	5	5	NUM
biomedich-166	112	3	.	.	PUNCT
biomedich-166	112	4	effect	effect	NOUN
biomedich-166	112	5	of	of	ADP
biomedich-166	112	6	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	112	7	-	-	PUNCT
biomedich-166	112	8	piperaquine	piperaquine	NOUN
biomedich-166	112	9	on	on	ADP
biomedich-166	112	10	lipid	lipid	ADJ
biomedich-166	112	11	parameters	parameter	NOUN
biomedich-166	112	12	of	of	ADP
biomedich-166	112	13	mice	mouse	NOUN
biomedich-166	112	14	infected	infect	VERB
biomedich-166	112	15	with	with	ADP
biomedich-166	112	16	plasmodium	plasmodium	NOUN
biomedich-166	112	17	berghei	berghei	PROPN
biomedich-166	112	18	.	.	PUNCT
biomedich-166	113	1	group	group	NOUN
biomedich-166	113	2	tg	tg	PROPN
biomedich-166	113	3	(	(	PUNCT
biomedich-166	113	4	mg	mg	PROPN
biomedich-166	113	5	/	/	SYM
biomedich-166	113	6	dl	dl	NOUN
biomedich-166	113	7	)	)	PUNCT
biomedich-166	113	8	tchol	tchol	NOUN
biomedich-166	113	9	(	(	PUNCT
biomedich-166	113	10	mg	mg	PROPN
biomedich-166	113	11	/	/	SYM
biomedich-166	113	12	dl	dl	NOUN
biomedich-166	113	13	)	)	PUNCT
biomedich-166	113	14	hdl	hdl	PROPN
biomedich-166	113	15	-	-	PUNCT
biomedich-166	113	16	c	c	PROPN
biomedich-166	113	17	(	(	PUNCT
biomedich-166	113	18	mg	mg	PROPN
biomedich-166	113	19	/	/	SYM
biomedich-166	113	20	dl	dl	NOUN
biomedich-166	113	21	)	)	PUNCT
biomedich-166	113	22	ldl	ldl	NOUN
biomedich-166	113	23	(	(	PUNCT
biomedich-166	113	24	mg	mg	PROPN
biomedich-166	113	25	/	/	SYM
biomedich-166	113	26	dl	dl	PROPN
biomedich-166	113	27	)	)	PUNCT
biomedich-166	113	28	nc	nc	PROPN
biomedich-166	113	29	80.8±7.03	80.8±7.03	NUM
biomedich-166	113	30	110.8±11.4	110.8±11.4	NUM
biomedich-166	113	31	50.4±4.00	50.4±4.00	NUM
biomedich-166	113	32	44.2±3.11	44.2±3.11	NUM
biomedich-166	113	33	pc	pc	NOUN
biomedich-166	113	34	250.3±18.9a	250.3±18.9a	NUM
biomedich-166	113	35	273.4±18.0	273.4±18.0	NOUN
biomedich-166	113	36	a	a	DET
biomedich-166	113	37	22.2±1.41	22.2±1.41	NUM
biomedich-166	113	38	a	a	DET
biomedich-166	113	39	201.1±18	201.1±18	NOUN
biomedich-166	113	40	.	.	PUNCT
biomedich-166	114	1	a	a	DET
biomedich-166	114	2	cq	cq	NOUN
biomedich-166	115	1	150.1±5.87	150.1±5.87	NUM
biomedich-166	116	1	b	b	PROPN
biomedich-166	116	2	181.6±22.4	181.6±22.4	NUM
biomedich-166	116	3	b	b	NOUN
biomedich-166	116	4	39.7±4.63	39.7±4.63	NUM
biomedich-166	116	5	b	b	SYM
biomedich-166	116	6	111.9±11.6	111.9±11.6	NUM
biomedich-166	116	7	b	b	X
biomedich-166	116	8	dx	dx	PROPN
biomedich-166	116	9	200.7±3.03	200.7±3.03	NUM
biomedich-166	116	10	c	c	NOUN
biomedich-166	116	11	220.0±12.0	220.0±12.0	NOUN
biomedich-166	116	12	c	c	NOUN
biomedich-166	116	13	30.6±4.22	30.6±4.22	NUM
biomedich-166	116	14	c	c	NOUN
biomedich-166	116	15	149.3±15.0	149.3±15.0	NUM
biomedich-166	116	16	c	c	NOUN
biomedich-166	116	17	d	d	NOUN
biomedich-166	116	18	-	-	PUNCT
biomedich-166	116	19	p	p	X
biomedich-166	116	20	159.0±4.87b	159.0±4.87b	NUM
biomedich-166	116	21	170.7±13.5b	170.7±13.5b	NUM
biomedich-166	116	22	38.7±4.00b	38.7±4.00b	NUM
biomedich-166	117	1	100.2±12.5b	100.2±12.5b	NUM
biomedich-166	117	2	d	d	X
biomedich-166	117	3	-	-	PUNCT
biomedich-166	117	4	p	p	PROPN
biomedich-166	117	5	-	-	PUNCT
biomedich-166	117	6	dx	dx	NOUN
biomedich-166	117	7	97.4±8.88d	97.4±8.88d	NUM
biomedich-166	117	8	127.7±10.6	127.7±10.6	ADJ
biomedich-166	117	9	d	d	NOUN
biomedich-166	117	10	47.9±5.43d	47.9±5.43d	NUM
biomedich-166	117	11	60.3±10.1d	60.3±10.1d	NOUN
biomedich-166	117	12	data	datum	NOUN
biomedich-166	117	13	presented	present	VERB
biomedich-166	117	14	as	as	ADP
biomedich-166	117	15	mean	mean	PROPN
biomedich-166	117	16	±	±	NUM
biomedich-166	117	17	sem	sem	PROPN
biomedich-166	117	18	,	,	PUNCT
biomedich-166	117	19	n=	n=	ADJ
biomedich-166	117	20	5	5	NUM
biomedich-166	117	21	,	,	PUNCT
biomedich-166	117	22	nc	nc	ADJ
biomedich-166	117	23	:	:	PUNCT
biomedich-166	117	24	normal	normal	ADJ
biomedich-166	117	25	control	control	NOUN
biomedich-166	117	26	,	,	PUNCT
biomedich-166	117	27	pc	pc	NOUN
biomedich-166	117	28	:	:	PUNCT
biomedich-166	117	29	negative	negative	ADJ
biomedich-166	117	30	control	control	NOUN
biomedich-166	117	31	,	,	PUNCT
biomedich-166	117	32	cq	cq	PROPN
biomedich-166	117	33	:	:	PUNCT
biomedich-166	117	34	chloroquine	chloroquine	PROPN
biomedich-166	117	35	,	,	PUNCT
biomedich-166	117	36	dx	dx	PROPN
biomedich-166	117	37	:	:	PUNCT
biomedich-166	117	38	doxycycline	doxycycline	NOUN
biomedich-166	117	39	,	,	PUNCT
biomedich-166	117	40	d	d	X
biomedich-166	117	41	-	-	PUNCT
biomedich-166	117	42	p	p	X
biomedich-166	117	43	:	:	PUNCT
biomedich-166	117	44	dihydroartemisininpiperaquine	dihydroartemisininpiperaquine	NOUN
biomedich-166	117	45	,	,	PUNCT
biomedich-166	117	46	tg	tg	PROPN
biomedich-166	117	47	:	:	PUNCT
biomedich-166	117	48	tryglyceride	tryglyceride	ADV
biomedich-166	117	49	,	,	PUNCT
biomedich-166	117	50	tchol	tchol	NOUN
biomedich-166	117	51	:	:	PUNCT
biomedich-166	117	52	total	total	ADJ
biomedich-166	117	53	cholesterol	cholesterol	NOUN
biomedich-166	117	54	,	,	PUNCT
biomedich-166	117	55	hdl	hdl	PROPN
biomedich-166	117	56	:	:	PUNCT
biomedich-166	117	57	high	high	ADJ
biomedich-166	117	58	density	density	NOUN
biomedich-166	117	59	lipoproteins	lipoprotein	NOUN
biomedich-166	117	60	,	,	PUNCT
biomedich-166	117	61	ldl	ldl	NOUN
biomedich-166	117	62	:	:	PUNCT
biomedich-166	117	63	low	low	ADJ
biomedich-166	117	64	density	density	NOUN
biomedich-166	117	65	lipoprotein	lipoprotein	ADJ
biomedich-166	117	66	.	.	PUNCT
biomedich-166	118	1	a	a	DET
biomedich-166	118	2	p<0.001	p<0.001	ADJ
biomedich-166	118	3	significant	significant	ADJ
biomedich-166	118	4	difference	difference	NOUN
biomedich-166	118	5	when	when	SCONJ
biomedich-166	118	6	compared	compare	VERB
biomedich-166	118	7	to	to	ADP
biomedich-166	118	8	nc	nc	PROPN
biomedich-166	118	9	,	,	PUNCT
biomedich-166	118	10	b	b	PROPN
biomedich-166	118	11	p<0.01	p<0.01	PROPN
biomedich-166	118	12	,	,	PUNCT
biomedich-166	118	13	c	c	NOUN
biomedich-166	118	14	p<0.05	p<0.05	NOUN
biomedich-166	118	15	,	,	PUNCT
biomedich-166	118	16	d	d	NOUN
biomedich-166	118	17	p<0.001	p<0.001	X
biomedich-166	118	18	significant	significant	ADJ
biomedich-166	118	19	difference	difference	NOUN
biomedich-166	118	20	when	when	SCONJ
biomedich-166	118	21	compared	compare	VERB
biomedich-166	118	22	to	to	ADP
biomedich-166	118	23	pc	pc	NOUN
biomedich-166	118	24	,	,	PUNCT
biomedich-166	118	25	sem	sem	ADJ
biomedich-166	118	26	:	:	PUNCT
biomedich-166	118	27	standard	standard	ADJ
biomedich-166	118	28	error	error	NOUN
biomedich-166	118	29	mean	mean	NOUN
biomedich-166	118	30	.	.	PUNCT
biomedich-166	119	1	discussion	discussion	NOUN
biomedich-166	119	2	malaria	malaria	NOUN
biomedich-166	119	3	is	be	AUX
biomedich-166	119	4	a	a	DET
biomedich-166	119	5	major	major	ADJ
biomedich-166	119	6	health	health	NOUN
biomedich-166	119	7	challenge	challenge	NOUN
biomedich-166	119	8	in	in	ADP
biomedich-166	119	9	developing	develop	VERB
biomedich-166	119	10	countries	country	NOUN
biomedich-166	119	11	of	of	ADP
biomedich-166	119	12	sub	sub	ADJ
biomedich-166	119	13	-	-	ADJ
biomedich-166	119	14	saharan	saharan	ADJ
biomedich-166	119	15	africa	africa	PROPN
biomedich-166	119	16	and	and	CCONJ
biomedich-166	119	17	south	south	PROPN
biomedich-166	119	18	east	east	PROPN
biomedich-166	119	19	asia	asia	PROPN
biomedich-166	119	20	.	.	PUNCT
biomedich-166	120	1	the	the	DET
biomedich-166	120	2	emergence	emergence	NOUN
biomedich-166	120	3	of	of	ADP
biomedich-166	120	4	widespread	widespread	ADJ
biomedich-166	120	5	resistance	resistance	NOUN
biomedich-166	120	6	of	of	ADP
biomedich-166	120	7	plasmodium	plasmodium	NOUN
biomedich-166	120	8	species	specie	NOUN
biomedich-166	120	9	to	to	ADP
biomedich-166	120	10	most	most	ADJ
biomedich-166	120	11	antimalarial	antimalarial	ADJ
biomedich-166	120	12	drugs	drug	NOUN
biomedich-166	120	13	,	,	PUNCT
biomedich-166	120	14	the	the	DET
biomedich-166	120	15	increasing	increase	VERB
biomedich-166	120	16	insecticide	insecticide	NOUN
biomedich-166	120	17	resistance	resistance	NOUN
biomedich-166	120	18	by	by	ADP
biomedich-166	120	19	mosquitoes	mosquito	NOUN
biomedich-166	120	20	,	,	PUNCT
biomedich-166	120	21	and	and	CCONJ
biomedich-166	120	22	the	the	DET
biomedich-166	120	23	lack	lack	NOUN
biomedich-166	120	24	of	of	ADP
biomedich-166	120	25	vaccines	vaccine	NOUN
biomedich-166	120	26	have	have	AUX
biomedich-166	120	27	made	make	VERB
biomedich-166	120	28	the	the	DET
biomedich-166	120	29	fight	fight	NOUN
biomedich-166	120	30	against	against	ADP
biomedich-166	120	31	malaria	malaria	NOUN
biomedich-166	120	32	seriously	seriously	ADV
biomedich-166	120	33	tasking	task	VERB
biomedich-166	120	34	(	(	PUNCT
biomedich-166	120	35	beeson	beeson	PROPN
biomedich-166	120	36	et	et	PROPN
biomedich-166	120	37	al	al	PROPN
biomedich-166	120	38	.	.	PROPN
biomedich-166	120	39	,	,	PUNCT
biomedich-166	120	40	2016	2016	NUM
biomedich-166	120	41	;	;	PUNCT
biomedich-166	120	42	joseph	joseph	PROPN
biomedich-166	120	43	et	et	PROPN
biomedich-166	120	44	al	al	PROPN
biomedich-166	120	45	.	.	PROPN
biomedich-166	120	46	,	,	PUNCT
biomedich-166	120	47	2020	2020	NUM
biomedich-166	120	48	)	)	PUNCT
biomedich-166	120	49	.	.	PUNCT
biomedich-166	121	1	hence	hence	ADV
biomedich-166	121	2	there	there	PRON
biomedich-166	121	3	is	be	VERB
biomedich-166	121	4	an	an	DET
biomedich-166	121	5	urgent	urgent	ADJ
biomedich-166	121	6	need	need	NOUN
biomedich-166	121	7	to	to	PART
biomedich-166	121	8	discover	discover	VERB
biomedich-166	121	9	alternative	alternative	ADJ
biomedich-166	121	10	drugs	drug	NOUN
biomedich-166	121	11	with	with	ADP
biomedich-166	121	12	novel	novel	ADJ
biomedich-166	121	13	modes	mode	NOUN
biomedich-166	121	14	of	of	ADP
biomedich-166	121	15	action	action	NOUN
biomedich-166	121	16	or	or	CCONJ
biomedich-166	121	17	a	a	DET
biomedich-166	121	18	combination	combination	NOUN
biomedich-166	121	19	of	of	ADP
biomedich-166	121	20	currently	currently	ADV
biomedich-166	121	21	existing	exist	VERB
biomedich-166	121	22	antimalarial	antimalarial	ADJ
biomedich-166	121	23	drugs	drug	NOUN
biomedich-166	121	24	to	to	PART
biomedich-166	121	25	overcome	overcome	VERB
biomedich-166	121	26	these	these	DET
biomedich-166	121	27	challenges	challenge	NOUN
biomedich-166	121	28	.	.	PUNCT
biomedich-166	122	1	the	the	DET
biomedich-166	122	2	present	present	ADJ
biomedich-166	122	3	study	study	NOUN
biomedich-166	122	4	,	,	PUNCT
biomedich-166	122	5	assessed	assess	VERB
biomedich-166	122	6	whether	whether	SCONJ
biomedich-166	122	7	antimalarial	antimalarial	ADJ
biomedich-166	122	8	activity	activity	NOUN
biomedich-166	122	9	of	of	ADP
biomedich-166	122	10	d	d	PROPN
biomedich-166	122	11	-	-	PUNCT
biomedich-166	122	12	p	p	NOUN
biomedich-166	122	13	can	can	AUX
biomedich-166	122	14	be	be	AUX
biomedich-166	122	15	augmented	augment	VERB
biomedich-166	122	16	by	by	ADP
biomedich-166	122	17	dx	dx	PROPN
biomedich-166	122	18	in	in	ADP
biomedich-166	122	19	mice	mouse	NOUN
biomedich-166	122	20	infected	infect	VERB
biomedich-166	122	21	with	with	ADP
biomedich-166	122	22	p.	p.	PROPN
biomedich-166	122	23	berghei	berghei	PROPN
biomedich-166	122	24	.	.	PUNCT
biomedich-166	123	1	this	this	DET
biomedich-166	123	2	study	study	NOUN
biomedich-166	123	3	used	use	VERB
biomedich-166	123	4	invivo	invivo	PROPN
biomedich-166	123	5	model	model	NOUN
biomedich-166	123	6	,	,	PUNCT
biomedich-166	123	7	because	because	SCONJ
biomedich-166	123	8	it	it	PRON
biomedich-166	123	9	takes	take	VERB
biomedich-166	123	10	into	into	ADP
biomedich-166	123	11	cognizance	cognizance	NOUN
biomedich-166	123	12	the	the	DET
biomedich-166	123	13	possible	possible	ADJ
biomedich-166	123	14	prodrug	prodrug	NOUN
biomedich-166	123	15	effect	effect	NOUN
biomedich-166	123	16	and	and	CCONJ
biomedich-166	123	17	the	the	DET
biomedich-166	123	18	involvement	involvement	NOUN
biomedich-166	123	19	of	of	ADP
biomedich-166	123	20	the	the	DET
biomedich-166	123	21	immune	immune	ADJ
biomedich-166	123	22	system	system	NOUN
biomedich-166	123	23	in	in	ADP
biomedich-166	123	24	eradicating	eradicate	VERB
biomedich-166	123	25	malaria	malaria	NOUN
biomedich-166	123	26	infection	infection	NOUN
biomedich-166	123	27	.	.	PUNCT
biomedich-166	124	1	p.	p.	NOUN
biomedich-166	124	2	berghei	berghei	PROPN
biomedich-166	124	3	has	have	AUX
biomedich-166	124	4	been	be	AUX
biomedich-166	124	5	used	use	VERB
biomedich-166	124	6	in	in	ADP
biomedich-166	124	7	antiplasmodial	antiplasmodial	ADJ
biomedich-166	124	8	studies	study	NOUN
biomedich-166	124	9	in	in	ADP
biomedich-166	124	10	predicting	predict	VERB
biomedich-166	124	11	experimental	experimental	ADJ
biomedich-166	124	12	treatment	treatment	NOUN
biomedich-166	124	13	outcomes	outcome	NOUN
biomedich-166	124	14	and	and	CCONJ
biomedich-166	124	15	hence	hence	ADV
biomedich-166	124	16	was	be	AUX
biomedich-166	124	17	appropriately	appropriately	ADV
biomedich-166	124	18	used	use	VERB
biomedich-166	124	19	for	for	ADP
biomedich-166	124	20	the	the	DET
biomedich-166	124	21	study	study	NOUN
biomedich-166	124	22	(	(	PUNCT
biomedich-166	124	23	satish	satish	PROPN
biomedich-166	124	24	et	et	PROPN
biomedich-166	124	25	al	al	PROPN
biomedich-166	124	26	.	.	PROPN
biomedich-166	124	27	,	,	PUNCT
biomedich-166	124	28	2017	2017	NUM
biomedich-166	124	29	)	)	PUNCT
biomedich-166	124	30	.	.	PUNCT
biomedich-166	125	1	this	this	DET
biomedich-166	125	2	study	study	NOUN
biomedich-166	125	3	used	use	VERB
biomedich-166	125	4	suppressive	suppressive	ADJ
biomedich-166	125	5	test	test	NOUN
biomedich-166	125	6	which	which	PRON
biomedich-166	125	7	determines	determine	VERB
biomedich-166	125	8	the	the	DET
biomedich-166	125	9	activity	activity	NOUN
biomedich-166	125	10	of	of	ADP
biomedich-166	125	11	a	a	DET
biomedich-166	125	12	drug	drug	NOUN
biomedich-166	125	13	candidate	candidate	NOUN
biomedich-166	125	14	on	on	ADP
biomedich-166	125	15	early	early	ADJ
biomedich-166	125	16	infection	infection	NOUN
biomedich-166	125	17	and	and	CCONJ
biomedich-166	125	18	curative	curative	ADJ
biomedich-166	125	19	test	test	NOUN
biomedich-166	125	20	,	,	PUNCT
biomedich-166	125	21	which	which	PRON
biomedich-166	125	22	evaluates	evaluate	VERB
biomedich-166	125	23	the	the	DET
biomedich-166	125	24	curative	curative	ADJ
biomedich-166	125	25	activity	activity	NOUN
biomedich-166	125	26	of	of	ADP
biomedich-166	125	27	a	a	DET
biomedich-166	125	28	drug	drug	NOUN
biomedich-166	125	29	candidate	candidate	NOUN
biomedich-166	125	30	on	on	ADP
biomedich-166	125	31	established	establish	VERB
biomedich-166	125	32	infection	infection	NOUN
biomedich-166	125	33	(	(	PUNCT
biomedich-166	125	34	mekonnen	mekonnen	NOUN
biomedich-166	125	35	,	,	PUNCT
biomedich-166	125	36	2015	2015	NUM
biomedich-166	125	37	;	;	PUNCT
biomedich-166	125	38	hiben	hiben	PROPN
biomedich-166	125	39	et	et	PROPN
biomedich-166	125	40	al	al	PROPN
biomedich-166	125	41	.	.	PROPN
biomedich-166	125	42	,	,	PUNCT
biomedich-166	125	43	2016	2016	NUM
biomedich-166	125	44	)	)	PUNCT
biomedich-166	125	45	.	.	PUNCT
biomedich-166	126	1	in	in	ADP
biomedich-166	126	2	the	the	DET
biomedich-166	126	3	present	present	ADJ
biomedich-166	126	4	study	study	NOUN
biomedich-166	126	5	,	,	PUNCT
biomedich-166	126	6	in	in	ADP
biomedich-166	126	7	the	the	DET
biomedich-166	126	8	curative	curative	ADJ
biomedich-166	126	9	test	test	NOUN
biomedich-166	126	10	,	,	PUNCT
biomedich-166	126	11	d	d	X
biomedich-166	126	12	-	-	PUNCT
biomedich-166	126	13	p	p	X
biomedich-166	126	14	-	-	PUNCT
biomedich-166	126	15	dx	dx	PROPN
biomedich-166	126	16	decreased	decrease	VERB
biomedich-166	126	17	percentage	percentage	NOUN
biomedich-166	126	18	parasitemia	parasitemia	NOUN
biomedich-166	126	19	levels	level	NOUN
biomedich-166	126	20	most	most	ADV
biomedich-166	126	21	when	when	SCONJ
biomedich-166	126	22	compared	compare	VERB
biomedich-166	126	23	to	to	ADP
biomedich-166	126	24	individual	individual	ADJ
biomedich-166	126	25	doses	dose	NOUN
biomedich-166	126	26	of	of	ADP
biomedich-166	126	27	d	d	PROPN
biomedich-166	126	28	-	-	PUNCT
biomedich-166	126	29	p	p	X
biomedich-166	126	30	,	,	PUNCT
biomedich-166	126	31	dx	dx	PROPN
biomedich-166	126	32	and	and	CCONJ
biomedich-166	126	33	cq	cq	PROPN
biomedich-166	126	34	.	.	PUNCT
biomedich-166	127	1	the	the	DET
biomedich-166	127	2	observed	observed	ADJ
biomedich-166	127	3	parasitemia	parasitemia	NOUN
biomedich-166	127	4	inhibitions	inhibition	VERB
biomedich-166	127	5	in	in	ADP
biomedich-166	127	6	the	the	DET
biomedich-166	127	7	curative	curative	ADJ
biomedich-166	127	8	test	test	NOUN
biomedich-166	127	9	were	be	AUX
biomedich-166	127	10	64.9	64.9	NUM
biomedich-166	127	11	%	%	NOUN
biomedich-166	127	12	,	,	PUNCT
biomedich-166	127	13	71.1	71.1	NUM
biomedich-166	127	14	%	%	NOUN
biomedich-166	127	15	,	,	PUNCT
biomedich-166	127	16	93.6	93.6	NUM
biomedich-166	127	17	%	%	NOUN
biomedich-166	127	18	in	in	ADP
biomedich-166	127	19	dx	dx	PROPN
biomedich-166	127	20	,	,	PUNCT
biomedich-166	127	21	d	d	PROPN
biomedich-166	127	22	-	-	PUNCT
biomedich-166	127	23	p	p	X
biomedich-166	127	24	,	,	PUNCT
biomedich-166	127	25	and	and	CCONJ
biomedich-166	127	26	d	d	X
biomedich-166	127	27	-	-	ADJ
biomedich-166	127	28	p	p	NUM
biomedich-166	127	29	-	-	PUNCT
biomedich-166	127	30	dx	dx	NOUN
biomedich-166	127	31	-	-	PUNCT
biomedich-166	127	32	treated	treat	VERB
biomedich-166	127	33	mice	mouse	NOUN
biomedich-166	127	34	,	,	PUNCT
biomedich-166	127	35	respectively	respectively	ADV
biomedich-166	127	36	.	.	PUNCT
biomedich-166	128	1	also	also	ADV
biomedich-166	128	2	,	,	PUNCT
biomedich-166	128	3	in	in	ADP
biomedich-166	128	4	the	the	DET
biomedich-166	128	5	suppressive	suppressive	ADJ
biomedich-166	128	6	and	and	CCONJ
biomedich-166	128	7	prophylactic	prophylactic	ADJ
biomedich-166	128	8	tests	test	NOUN
biomedich-166	128	9	,	,	PUNCT
biomedich-166	128	10	best	good	ADJ
biomedich-166	128	11	decreases	decrease	NOUN
biomedich-166	128	12	in	in	ADP
biomedich-166	128	13	percentage	percentage	NOUN
biomedich-166	128	14	parasitemia	parasitemia	NOUN
biomedich-166	128	15	levels	level	NOUN
biomedich-166	128	16	occurred	occur	VERB
biomedich-166	128	17	in	in	ADP
biomedich-166	128	18	d	d	PROPN
biomedich-166	128	19	-	-	PUNCT
biomedich-166	128	20	p	p	NOUN
biomedich-166	128	21	-	-	PUNCT
biomedich-166	128	22	dxtreated	dxtreate	VERB
biomedich-166	128	23	mice	mouse	NOUN
biomedich-166	128	24	in	in	ADP
biomedich-166	128	25	comparison	comparison	NOUN
biomedich-166	128	26	to	to	ADP
biomedich-166	128	27	individual	individual	ADJ
biomedich-166	128	28	doses	dose	NOUN
biomedich-166	128	29	of	of	ADP
biomedich-166	128	30	dx	dx	PROPN
biomedich-166	128	31	,	,	PUNCT
biomedich-166	128	32	d	d	PROPN
biomedich-166	128	33	-	-	PUNCT
biomedich-166	128	34	p	p	X
biomedich-166	128	35	,	,	PUNCT
biomedich-166	128	36	and	and	CCONJ
biomedich-166	128	37	cq	cq	NOUN
biomedich-166	128	38	.	.	PROPN
biomedich-166	129	1	in	in	ADP
biomedich-166	129	2	the	the	DET
biomedich-166	129	3	suppressive	suppressive	ADJ
biomedich-166	129	4	test	test	NOUN
biomedich-166	129	5	,	,	PUNCT
biomedich-166	129	6	66.5	66.5	NUM
biomedich-166	129	7	%	%	NOUN
biomedich-166	129	8	,	,	PUNCT
biomedich-166	129	9	75.0	75.0	NUM
biomedich-166	129	10	%	%	NOUN
biomedich-166	129	11	,	,	PUNCT
biomedich-166	129	12	and	and	CCONJ
biomedich-166	129	13	95.1	95.1	NUM
biomedich-166	129	14	%	%	NOUN
biomedich-166	129	15	,	,	PUNCT
biomedich-166	129	16	parasitemia	parasitemia	NOUN
biomedich-166	129	17	inhibitions	inhibition	NOUN
biomedich-166	129	18	were	be	AUX
biomedich-166	129	19	observed	observe	VERB
biomedich-166	129	20	in	in	ADP
biomedich-166	129	21	dx	dx	PROPN
biomedich-166	129	22	,	,	PUNCT
biomedich-166	129	23	dp	dp	PROPN
biomedich-166	129	24	,	,	PUNCT
biomedich-166	129	25	and	and	CCONJ
biomedich-166	129	26	d	d	X
biomedich-166	129	27	-	-	ADJ
biomedich-166	129	28	p	p	X
biomedich-166	129	29	-	-	PUNCT
biomedich-166	129	30	dx	dx	NOUN
biomedich-166	129	31	treated	treat	VERB
biomedich-166	129	32	mice	mouse	NOUN
biomedich-166	129	33	respectively	respectively	ADV
biomedich-166	129	34	.	.	PUNCT
biomedich-166	130	1	in	in	ADP
biomedich-166	130	2	view	view	NOUN
biomedich-166	130	3	of	of	ADP
biomedich-166	130	4	the	the	DET
biomedich-166	130	5	antiplasmodial	antiplasmodial	ADJ
biomedich-166	130	6	activity	activity	NOUN
biomedich-166	130	7	of	of	ADP
biomedich-166	130	8	d	d	PROPN
biomedich-166	130	9	-	-	PUNCT
biomedich-166	130	10	p	p	NOUN
biomedich-166	130	11	-	-	PUNCT
biomedich-166	130	12	dx	dx	PROPN
biomedich-166	130	13	observed	observe	VERB
biomedich-166	130	14	in	in	ADP
biomedich-166	130	15	the	the	DET
biomedich-166	130	16	georgewill	georgewill	PROPN
biomedich-166	130	17	&	&	CCONJ
biomedich-166	130	18	adikwu	adikwu	PROPN
biomedich-166	130	19	–	–	PUNCT
biomedich-166	130	20	repurposing	repurpose	VERB
biomedich-166	130	21	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	130	22	-	-	PUNCT
biomedich-166	130	23	piperaquine	piperaquine	NOUN
biomedich-166	130	24	-	-	PUNCT
biomedich-166	130	25	doxycycline	doxycycline	NOUN
biomedich-166	130	26	as	as	ADP
biomedich-166	130	27	…	…	PUNCT
biomedich-166	130	28	139	139	NUM
biomedich-166	130	29	present	present	ADJ
biomedich-166	130	30	study	study	NOUN
biomedich-166	130	31	,	,	PUNCT
biomedich-166	130	32	the	the	DET
biomedich-166	130	33	ability	ability	NOUN
biomedich-166	130	34	of	of	ADP
biomedich-166	130	35	d	d	PROPN
biomedich-166	130	36	-	-	PUNCT
biomedich-166	130	37	p	p	X
biomedich-166	130	38	-	-	PUNCT
biomedich-166	130	39	dx	dx	NOUN
biomedich-166	130	40	to	to	PART
biomedich-166	130	41	prolong	prolong	VERB
biomedich-166	130	42	mst	mst	PROPN
biomedich-166	130	43	in	in	ADP
biomedich-166	130	44	mice	mouse	NOUN
biomedich-166	130	45	was	be	AUX
biomedich-166	130	46	also	also	ADV
biomedich-166	130	47	evaluated	evaluate	VERB
biomedich-166	130	48	.	.	PUNCT
biomedich-166	131	1	treatment	treatment	NOUN
biomedich-166	131	2	with	with	ADP
biomedich-166	131	3	d	d	PROPN
biomedich-166	131	4	-	-	PUNCT
biomedich-166	131	5	p	p	NUM
biomedich-166	131	6	-	-	PUNCT
biomedich-166	131	7	dx	dx	NOUN
biomedich-166	131	8	prolonged	prolong	VERB
biomedich-166	131	9	mst	mst	PROPN
biomedich-166	131	10	in	in	ADP
biomedich-166	131	11	the	the	DET
biomedich-166	131	12	curative	curative	ADJ
biomedich-166	131	13	,	,	PUNCT
biomedich-166	131	14	prophylactic	prophylactic	ADJ
biomedich-166	131	15	and	and	CCONJ
biomedich-166	131	16	suppressive	suppressive	ADJ
biomedich-166	131	17	tests	test	NOUN
biomedich-166	131	18	.	.	PUNCT
biomedich-166	132	1	the	the	DET
biomedich-166	132	2	prolongation	prolongation	NOUN
biomedich-166	132	3	of	of	ADP
biomedich-166	132	4	mst	mst	PROPN
biomedich-166	132	5	by	by	ADP
biomedich-166	132	6	d	d	PROPN
biomedich-166	132	7	-	-	PUNCT
biomedich-166	132	8	p	p	X
biomedich-166	132	9	-	-	PUNCT
biomedich-166	132	10	dx	dx	PROPN
biomedich-166	132	11	was	be	AUX
biomedich-166	132	12	best	good	ADJ
biomedich-166	132	13	when	when	SCONJ
biomedich-166	132	14	compared	compare	VERB
biomedich-166	132	15	to	to	ADP
biomedich-166	132	16	individual	individual	ADJ
biomedich-166	132	17	doses	dose	NOUN
biomedich-166	132	18	of	of	ADP
biomedich-166	132	19	dx	dx	PROPN
biomedich-166	132	20	,	,	PUNCT
biomedich-166	132	21	dp	dp	PROPN
biomedich-166	132	22	,	,	PUNCT
biomedich-166	132	23	and	and	CCONJ
biomedich-166	133	1	cq	cq	NOUN
biomedich-166	133	2	.	.	PUNCT
biomedich-166	134	1	hematological	hematological	ADJ
biomedich-166	134	2	abnormalities	abnormality	NOUN
biomedich-166	134	3	like	like	ADP
biomedich-166	134	4	anemia	anemia	NOUN
biomedich-166	134	5	caused	cause	VERB
biomedich-166	134	6	by	by	ADP
biomedich-166	134	7	erythrocyte	erythrocyte	ADJ
biomedich-166	134	8	destruction	destruction	NOUN
biomedich-166	134	9	are	be	AUX
biomedich-166	134	10	common	common	ADJ
biomedich-166	134	11	characteristics	characteristic	NOUN
biomedich-166	134	12	of	of	ADP
biomedich-166	134	13	p.	p.	PROPN
biomedich-166	134	14	berghei	berghei	PROPN
biomedich-166	134	15	-	-	PUNCT
biomedich-166	134	16	infected	infect	VERB
biomedich-166	134	17	mice	mouse	NOUN
biomedich-166	134	18	.	.	PUNCT
biomedich-166	135	1	rodent	rodent	ADJ
biomedich-166	135	2	malaria	malaria	NOUN
biomedich-166	135	3	causes	cause	VERB
biomedich-166	135	4	parasite	parasite	NOUN
biomedich-166	135	5	-	-	PUNCT
biomedich-166	135	6	induced	induced	ADJ
biomedich-166	135	7	decrease	decrease	NOUN
biomedich-166	135	8	in	in	ADP
biomedich-166	135	9	pcv	pcv	NOUN
biomedich-166	135	10	,	,	PUNCT
biomedich-166	135	11	which	which	PRON
biomedich-166	135	12	occurs	occur	VERB
biomedich-166	135	13	approximately	approximately	ADV
biomedich-166	135	14	48	48	NUM
biomedich-166	135	15	h	h	NOUN
biomedich-166	135	16	post	post	NOUN
biomedich-166	135	17	-	-	NOUN
biomedich-166	135	18	infection	infection	NOUN
biomedich-166	135	19	(	(	PUNCT
biomedich-166	135	20	nardos	nardo	NOUN
biomedich-166	135	21	and	and	CCONJ
biomedich-166	135	22	makonnen	makonnen	NOUN
biomedich-166	135	23	,	,	PUNCT
biomedich-166	135	24	2017	2017	NUM
biomedich-166	135	25	)	)	PUNCT
biomedich-166	135	26	.	.	PUNCT
biomedich-166	136	1	in	in	ADP
biomedich-166	136	2	the	the	DET
biomedich-166	136	3	present	present	ADJ
biomedich-166	136	4	study	study	NOUN
biomedich-166	136	5	,	,	PUNCT
biomedich-166	136	6	notable	notable	ADJ
biomedich-166	136	7	signs	sign	NOUN
biomedich-166	136	8	of	of	ADP
biomedich-166	136	9	anemia	anemia	NOUN
biomedich-166	136	10	marked	mark	VERB
biomedich-166	136	11	by	by	ADP
biomedich-166	136	12	low	low	ADJ
biomedich-166	136	13	levels	level	NOUN
biomedich-166	136	14	of	of	ADP
biomedich-166	136	15	hb	hb	PROPN
biomedich-166	136	16	,	,	PUNCT
biomedich-166	136	17	pcv	pcv	NOUN
biomedich-166	136	18	rbcs	rbc	NOUN
biomedich-166	136	19	and	and	CCONJ
biomedich-166	136	20	increased	increase	VERB
biomedich-166	136	21	wbcs	wbc	NOUN
biomedich-166	136	22	levels	level	NOUN
biomedich-166	136	23	were	be	AUX
biomedich-166	136	24	observed	observe	VERB
biomedich-166	136	25	in	in	ADP
biomedich-166	136	26	p.	p.	NOUN
biomedich-166	136	27	bergheiinfected	bergheiinfecte	VERB
biomedich-166	136	28	mice	mouse	NOUN
biomedich-166	136	29	.	.	PUNCT
biomedich-166	137	1	however	however	ADV
biomedich-166	137	2	,	,	PUNCT
biomedich-166	137	3	p.	p.	PROPN
biomedich-166	137	4	bergheiinduced	bergheiinduced	PROPN
biomedich-166	137	5	anemia	anemia	NOUN
biomedich-166	137	6	was	be	AUX
biomedich-166	137	7	curtailed	curtail	VERB
biomedich-166	137	8	in	in	ADP
biomedich-166	137	9	d	d	PROPN
biomedich-166	137	10	-	-	PUNCT
biomedich-166	137	11	p	p	NOUN
biomedich-166	137	12	-	-	PUNCT
biomedich-166	137	13	dx	dx	NOUN
biomedich-166	137	14	treated	treat	VERB
biomedich-166	137	15	mice	mouse	NOUN
biomedich-166	137	16	when	when	SCONJ
biomedich-166	137	17	compared	compare	VERB
biomedich-166	137	18	to	to	ADP
biomedich-166	137	19	individual	individual	ADJ
biomedich-166	137	20	doses	dose	NOUN
biomedich-166	137	21	of	of	ADP
biomedich-166	137	22	dx	dx	PROPN
biomedich-166	137	23	,	,	PUNCT
biomedich-166	137	24	d	d	PROPN
biomedich-166	137	25	-	-	PUNCT
biomedich-166	137	26	p	p	X
biomedich-166	137	27	,	,	PUNCT
biomedich-166	137	28	and	and	CCONJ
biomedich-166	137	29	cq	cq	NOUN
biomedich-166	137	30	.	.	PUNCT
biomedich-166	138	1	studies	study	NOUN
biomedich-166	138	2	have	have	AUX
biomedich-166	138	3	reported	report	VERB
biomedich-166	138	4	that	that	SCONJ
biomedich-166	138	5	changes	change	NOUN
biomedich-166	138	6	in	in	ADP
biomedich-166	138	7	serum	serum	NOUN
biomedich-166	138	8	lipids	lipid	NOUN
biomedich-166	138	9	could	could	AUX
biomedich-166	138	10	be	be	AUX
biomedich-166	138	11	possible	possible	ADJ
biomedich-166	138	12	features	feature	NOUN
biomedich-166	138	13	of	of	ADP
biomedich-166	138	14	malaria	malaria	NOUN
biomedich-166	138	15	(	(	PUNCT
biomedich-166	138	16	visser	visser	PROPN
biomedich-166	138	17	et	et	PROPN
biomedich-166	138	18	al	al	PROPN
biomedich-166	138	19	.	.	PROPN
biomedich-166	138	20	,	,	PUNCT
biomedich-166	138	21	2013	2013	NUM
biomedich-166	138	22	)	)	PUNCT
biomedich-166	138	23	.	.	PUNCT
biomedich-166	139	1	the	the	DET
biomedich-166	139	2	present	present	ADJ
biomedich-166	139	3	study	study	NOUN
biomedich-166	139	4	observed	observe	VERB
biomedich-166	139	5	elevated	elevated	ADJ
biomedich-166	139	6	tchol	tchol	NOUN
biomedich-166	139	7	,	,	PUNCT
biomedich-166	139	8	tg	tg	PROPN
biomedich-166	139	9	,	,	PUNCT
biomedich-166	139	10	and	and	CCONJ
biomedich-166	139	11	ldl	ldl	NOUN
biomedich-166	139	12	-	-	PUNCT
biomedich-166	139	13	c	c	PROPN
biomedich-166	139	14	and	and	CCONJ
biomedich-166	139	15	decreased	decrease	VERB
biomedich-166	139	16	hdl	hdl	PROPN
biomedich-166	139	17	-	-	PUNCT
biomedich-166	139	18	c	c	PROPN
biomedich-166	139	19	levels	level	NOUN
biomedich-166	139	20	in	in	ADP
biomedich-166	139	21	p.	p.	PROPN
biomedich-166	139	22	berghei	berghei	PROPN
biomedich-166	139	23	-	-	PUNCT
biomedich-166	139	24	infected	infect	VERB
biomedich-166	139	25	mice	mouse	NOUN
biomedich-166	139	26	.	.	PUNCT
biomedich-166	140	1	however	however	ADV
biomedich-166	140	2	,	,	PUNCT
biomedich-166	140	3	d	d	X
biomedich-166	140	4	-	-	PUNCT
biomedich-166	140	5	p	p	X
biomedich-166	140	6	-	-	PUNCT
biomedich-166	140	7	dx	dx	NOUN
biomedich-166	140	8	restored	restore	VERB
biomedich-166	140	9	serum	serum	NOUN
biomedich-166	140	10	lipid	lipid	NOUN
biomedich-166	140	11	characterized	characterize	VERB
biomedich-166	140	12	by	by	ADP
biomedich-166	140	13	decreased	decrease	VERB
biomedich-166	140	14	tchol	tchol	NOUN
biomedich-166	140	15	,	,	PUNCT
biomedich-166	140	16	tg	tg	X
biomedich-166	140	17	,	,	PUNCT
biomedich-166	140	18	ldl	ldl	NOUN
biomedich-166	140	19	-	-	PUNCT
biomedich-166	140	20	c	c	PROPN
biomedich-166	140	21	and	and	CCONJ
biomedich-166	140	22	increased	increase	VERB
biomedich-166	140	23	hdl	hdl	PROPN
biomedich-166	140	24	-	-	PUNCT
biomedich-166	140	25	c	c	NOUN
biomedich-166	140	26	levels	level	NOUN
biomedich-166	140	27	.	.	PUNCT
biomedich-166	141	1	the	the	DET
biomedich-166	141	2	observed	observe	VERB
biomedich-166	141	3	antiplasmodial	antiplasmodial	ADJ
biomedich-166	141	4	effect	effect	NOUN
biomedich-166	141	5	of	of	ADP
biomedich-166	141	6	d	d	PROPN
biomedich-166	141	7	-	-	PUNCT
biomedich-166	141	8	p	p	X
biomedich-166	141	9	-	-	PUNCT
biomedich-166	141	10	dx	dx	PROPN
biomedich-166	141	11	may	may	AUX
biomedich-166	141	12	be	be	AUX
biomedich-166	141	13	due	due	ADJ
biomedich-166	141	14	to	to	ADP
biomedich-166	141	15	different	different	ADJ
biomedich-166	141	16	modes	mode	NOUN
biomedich-166	141	17	of	of	ADP
biomedich-166	141	18	antiplasmodial	antiplasmodial	ADJ
biomedich-166	141	19	activity	activity	NOUN
biomedich-166	141	20	of	of	ADP
biomedich-166	141	21	the	the	DET
biomedich-166	141	22	partner	partner	NOUN
biomedich-166	141	23	drugs	drug	NOUN
biomedich-166	141	24	.	.	PUNCT
biomedich-166	142	1	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	142	2	acts	act	VERB
biomedich-166	142	3	through	through	ADP
biomedich-166	142	4	the	the	DET
biomedich-166	142	5	cleavage	cleavage	NOUN
biomedich-166	142	6	of	of	ADP
biomedich-166	142	7	the	the	DET
biomedich-166	142	8	endoperoxide	endoperoxide	ADJ
biomedich-166	142	9	bridge	bridge	NOUN
biomedich-166	142	10	and	and	CCONJ
biomedich-166	142	11	the	the	DET
biomedich-166	142	12	production	production	NOUN
biomedich-166	142	13	of	of	ADP
biomedich-166	142	14	free	free	ADJ
biomedich-166	142	15	radicals	radical	NOUN
biomedich-166	142	16	(	(	PUNCT
biomedich-166	142	17	meshnick	meshnick	PROPN
biomedich-166	142	18	,	,	PUNCT
biomedich-166	142	19	1994	1994	NUM
biomedich-166	142	20	)	)	PUNCT
biomedich-166	142	21	.	.	PUNCT
biomedich-166	143	1	piperaquine	piperaquine	PROPN
biomedich-166	143	2	is	be	AUX
biomedich-166	143	3	suggested	suggest	VERB
biomedich-166	143	4	to	to	PART
biomedich-166	143	5	have	have	VERB
biomedich-166	143	6	similar	similar	ADJ
biomedich-166	143	7	mode	mode	NOUN
biomedich-166	143	8	of	of	ADP
biomedich-166	143	9	action	action	NOUN
biomedich-166	143	10	as	as	ADP
biomedich-166	143	11	cq	cq	PROPN
biomedich-166	143	12	(	(	PUNCT
biomedich-166	143	13	meshnick	meshnick	PROPN
biomedich-166	143	14	,	,	PUNCT
biomedich-166	143	15	1994	1994	NUM
biomedich-166	143	16	)	)	PUNCT
biomedich-166	143	17	.	.	PUNCT
biomedich-166	144	1	in	in	ADP
biomedich-166	144	2	parasite	parasite	NOUN
biomedich-166	144	3	food	food	NOUN
biomedich-166	144	4	vacuole	vacuole	NOUN
biomedich-166	144	5	,	,	PUNCT
biomedich-166	144	6	concentrated	concentrate	VERB
biomedich-166	144	7	cq	cq	NOUN
biomedich-166	144	8	binds	bind	VERB
biomedich-166	144	9	free	free	ADJ
biomedich-166	144	10	hematin	hematin	AUX
biomedich-166	144	11	forming	form	VERB
biomedich-166	144	12	cqhematin	cqhematin	NOUN
biomedich-166	144	13	complex	complex	NOUN
biomedich-166	144	14	.	.	PUNCT
biomedich-166	145	1	this	this	PRON
biomedich-166	145	2	interferes	interfere	VERB
biomedich-166	145	3	with	with	ADP
biomedich-166	145	4	enzymatic	enzymatic	ADJ
biomedich-166	145	5	processes	process	NOUN
biomedich-166	145	6	in	in	ADP
biomedich-166	145	7	the	the	DET
biomedich-166	145	8	parasite	parasite	NOUN
biomedich-166	145	9	causing	cause	VERB
biomedich-166	145	10	parasite	parasite	ADJ
biomedich-166	145	11	death	death	NOUN
biomedich-166	145	12	(	(	PUNCT
biomedich-166	145	13	tärning	tärne	VERB
biomedich-166	145	14	et	et	PROPN
biomedich-166	145	15	al	al	PROPN
biomedich-166	145	16	.	.	PROPN
biomedich-166	145	17	,	,	PUNCT
biomedich-166	145	18	2007	2007	NUM
biomedich-166	145	19	)	)	PUNCT
biomedich-166	145	20	.	.	PUNCT
biomedich-166	146	1	the	the	DET
biomedich-166	146	2	antiplasmodial	antiplasmodial	ADJ
biomedich-166	146	3	mode	mode	NOUN
biomedich-166	146	4	of	of	ADP
biomedich-166	146	5	action	action	NOUN
biomedich-166	146	6	of	of	ADP
biomedich-166	146	7	dx	dx	PROPN
biomedich-166	146	8	is	be	AUX
biomedich-166	146	9	not	not	PART
biomedich-166	146	10	clear	clear	ADJ
biomedich-166	146	11	,	,	PUNCT
biomedich-166	146	12	but	but	CCONJ
biomedich-166	146	13	studies	study	NOUN
biomedich-166	146	14	suggested	suggest	VERB
biomedich-166	146	15	the	the	DET
biomedich-166	146	16	inhibition	inhibition	NOUN
biomedich-166	146	17	of	of	ADP
biomedich-166	146	18	mitochondrial	mitochondrial	ADJ
biomedich-166	146	19	protein	protein	NOUN
biomedich-166	146	20	,	,	PUNCT
biomedich-166	146	21	nucleotides	nucleotide	NOUN
biomedich-166	146	22	and	and	CCONJ
biomedich-166	146	23	deoxynucleotides	deoxynucleotide	NOUN
biomedich-166	146	24	syntheses	synthesis	NOUN
biomedich-166	146	25	in	in	ADP
biomedich-166	146	26	plasmodium	plasmodium	NOUN
biomedich-166	146	27	(	(	PUNCT
biomedich-166	146	28	yeo	yeo	PROPN
biomedich-166	146	29	et	et	PROPN
biomedich-166	146	30	al	al	PROPN
biomedich-166	146	31	.	.	PROPN
biomedich-166	146	32	,	,	PUNCT
biomedich-166	146	33	1997	1997	NUM
biomedich-166	146	34	;	;	PUNCT
biomedich-166	146	35	prapunwattana	prapunwattana	PROPN
biomedich-166	146	36	et	et	PROPN
biomedich-166	146	37	al	al	PROPN
biomedich-166	146	38	.	.	PROPN
biomedich-166	146	39	,	,	PUNCT
biomedich-166	146	40	1998	1998	NUM
biomedich-166	146	41	)	)	PUNCT
biomedich-166	146	42	.	.	PUNCT
biomedich-166	147	1	conclusion	conclusion	NOUN
biomedich-166	147	2	this	this	DET
biomedich-166	147	3	study	study	NOUN
biomedich-166	147	4	showed	show	VERB
biomedich-166	147	5	that	that	SCONJ
biomedich-166	147	6	d	d	X
biomedich-166	147	7	-	-	PUNCT
biomedich-166	147	8	p	p	X
biomedich-166	147	9	-	-	PUNCT
biomedich-166	147	10	dx	dx	PROPN
biomedich-166	147	11	produced	produce	VERB
biomedich-166	147	12	the	the	DET
biomedich-166	147	13	best	good	ADJ
biomedich-166	147	14	antiplasmodial	antiplasmodial	ADJ
biomedich-166	147	15	activity	activity	NOUN
biomedich-166	147	16	in	in	ADP
biomedich-166	147	17	p.	p.	PROPN
biomedich-166	147	18	berghei	berghei	PROPN
biomedich-166	147	19	-	-	PUNCT
biomedich-166	147	20	infected	infect	VERB
biomedich-166	147	21	mice	mouse	NOUN
biomedich-166	147	22	when	when	SCONJ
biomedich-166	147	23	compared	compare	VERB
biomedich-166	147	24	to	to	ADP
biomedich-166	147	25	individual	individual	ADJ
biomedich-166	147	26	doses	dose	NOUN
biomedich-166	147	27	of	of	ADP
biomedich-166	147	28	d	d	PROPN
biomedich-166	147	29	-	-	PUNCT
biomedich-166	147	30	p	p	X
biomedich-166	147	31	,	,	PUNCT
biomedich-166	147	32	dx	dx	PROPN
biomedich-166	147	33	and	and	CCONJ
biomedich-166	147	34	cq	cq	PROPN
biomedich-166	147	35	.	.	PUNCT
biomedich-166	148	1	also	also	ADV
biomedich-166	148	2	,	,	PUNCT
biomedich-166	148	3	alterations	alteration	NOUN
biomedich-166	148	4	in	in	ADP
biomedich-166	148	5	lipid	lipid	NOUN
biomedich-166	148	6	profile	profile	NOUN
biomedich-166	148	7	and	and	CCONJ
biomedich-166	148	8	hematological	hematological	ADJ
biomedich-166	148	9	parameters	parameter	NOUN
biomedich-166	148	10	were	be	AUX
biomedich-166	148	11	best	well	ADV
biomedich-166	148	12	restored	restore	VERB
biomedich-166	148	13	by	by	ADP
biomedich-166	148	14	d	d	PROPN
biomedich-166	148	15	-	-	PUNCT
biomedich-166	148	16	p	p	NOUN
biomedich-166	148	17	-	-	PUNCT
biomedich-166	148	18	dx	dx	NOUN
biomedich-166	148	19	when	when	SCONJ
biomedich-166	148	20	compared	compare	VERB
biomedich-166	148	21	to	to	ADP
biomedich-166	148	22	individual	individual	ADJ
biomedich-166	148	23	doses	dose	NOUN
biomedich-166	148	24	of	of	ADP
biomedich-166	148	25	d	d	PROPN
biomedich-166	148	26	-	-	PUNCT
biomedich-166	148	27	p	p	X
biomedich-166	148	28	,	,	PUNCT
biomedich-166	148	29	dx	dx	PROPN
biomedich-166	148	30	and	and	CCONJ
biomedich-166	148	31	cq	cq	PROPN
biomedich-166	148	32	.	.	PUNCT
biomedich-166	149	1	this	this	PRON
biomedich-166	149	2	shows	show	VERB
biomedich-166	149	3	that	that	SCONJ
biomedich-166	149	4	d	d	X
biomedich-166	149	5	-	-	PUNCT
biomedich-166	149	6	p	p	X
biomedich-166	149	7	-	-	PUNCT
biomedich-166	149	8	dx	dx	PROPN
biomedich-166	149	9	may	may	AUX
biomedich-166	149	10	be	be	AUX
biomedich-166	149	11	an	an	DET
biomedich-166	149	12	effective	effective	ADJ
biomedich-166	149	13	antimalarial	antimalarial	ADJ
biomedich-166	149	14	drug	drug	NOUN
biomedich-166	149	15	combination	combination	NOUN
biomedich-166	149	16	.	.	PUNCT
biomedich-166	150	1	acknowledgement	acknowledgement	NOUN
biomedich-166	150	2	:	:	PUNCT
biomedich-166	150	3	the	the	DET
biomedich-166	150	4	authors	author	NOUN
biomedich-166	150	5	appreciate	appreciate	VERB
biomedich-166	150	6	the	the	DET
biomedich-166	150	7	laboratory	laboratory	NOUN
biomedich-166	150	8	staff	staff	NOUN
biomedich-166	150	9	of	of	ADP
biomedich-166	150	10	the	the	DET
biomedich-166	150	11	department	department	PROPN
biomedich-166	150	12	of	of	ADP
biomedich-166	150	13	pharmacology	pharmacology	NOUN
biomedich-166	150	14	,	,	PUNCT
biomedich-166	150	15	faculty	faculty	NOUN
biomedich-166	150	16	of	of	ADP
biomedich-166	150	17	basic	basic	ADJ
biomedich-166	150	18	clinical	clinical	ADJ
biomedich-166	150	19	sciences	science	NOUN
biomedich-166	150	20	,	,	PUNCT
biomedich-166	150	21	university	university	NOUN
biomedich-166	150	22	of	of	ADP
biomedich-166	150	23	port	port	PROPN
biomedich-166	150	24	harcourt	harcourt	PROPN
biomedich-166	150	25	,	,	PUNCT
biomedich-166	150	26	nigeria	nigeria	PROPN
biomedich-166	150	27	.	.	PUNCT
biomedich-166	151	1	conflict	conflict	NOUN
biomedich-166	151	2	of	of	ADP
biomedich-166	151	3	interest	interest	NOUN
biomedich-166	151	4	:	:	PUNCT
biomedich-166	151	5	the	the	DET
biomedich-166	151	6	authors	author	NOUN
biomedich-166	151	7	declare	declare	VERB
biomedich-166	151	8	no	no	DET
biomedich-166	151	9	conflicts	conflict	NOUN
biomedich-166	151	10	of	of	ADP
biomedich-166	151	11	interest	interest	NOUN
biomedich-166	151	12	.	.	PUNCT
biomedich-166	152	1	financial	financial	ADJ
biomedich-166	152	2	disclosure	disclosure	NOUN
biomedich-166	152	3	:	:	PUNCT
biomedich-166	153	1	none	none	NOUN
biomedich-166	153	2	references	reference	NOUN
biomedich-166	153	3	amaratunga	amaratunga	VERB
biomedich-166	153	4	c	c	X
biomedich-166	153	5	,	,	PUNCT
biomedich-166	153	6	lim	lim	PROPN
biomedich-166	153	7	p	p	X
biomedich-166	153	8	,	,	PUNCT
biomedich-166	153	9	suon	suon	NOUN
biomedich-166	153	10	s	s	PART
biomedich-166	153	11	,	,	PUNCT
biomedich-166	153	12	sreng	sreng	NOUN
biomedich-166	153	13	,	,	PUNCT
biomedich-166	153	14	s	s	PROPN
biomedich-166	153	15	,	,	PUNCT
biomedich-166	153	16	mao	mao	NOUN
biomedich-166	153	17	s	s	PART
biomedich-166	153	18	,	,	PUNCT
biomedich-166	153	19	sopha	sopha	PROPN
biomedich-166	153	20	c	c	NOUN
biomedich-166	153	21	et	et	PROPN
biomedich-166	153	22	al	al	PROPN
biomedich-166	153	23	.	.	PUNCT
biomedich-166	153	24	(	(	PUNCT
biomedich-166	153	25	2016	2016	NUM
biomedich-166	153	26	)	)	PUNCT
biomedich-166	153	27	.	.	PUNCT
biomedich-166	154	1	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	154	2	–	–	PUNCT
biomedich-166	154	3	piperaquine	piperaquine	ADJ
biomedich-166	154	4	resistance	resistance	NOUN
biomedich-166	154	5	in	in	ADP
biomedich-166	154	6	plasmodium	plasmodium	NOUN
biomedich-166	154	7	falciparum	falciparum	ADJ
biomedich-166	154	8	malaria	malaria	NOUN
biomedich-166	154	9	in	in	ADP
biomedich-166	154	10	cambodia	cambodia	PROPN
biomedich-166	154	11	:	:	PUNCT
biomedich-166	154	12	a	a	DET
biomedich-166	154	13	multisite	multisite	ADJ
biomedich-166	154	14	prospective	prospective	ADJ
biomedich-166	154	15	cohort	cohort	NOUN
biomedich-166	154	16	study	study	NOUN
biomedich-166	154	17	.	.	PUNCT
biomedich-166	155	1	lancet	lancet	PROPN
biomedich-166	155	2	infect	infect	PROPN
biomedich-166	155	3	dis	dis	PROPN
biomedich-166	155	4	.	.	PUNCT
biomedich-166	156	1	16	16	NUM
biomedich-166	156	2	,	,	PUNCT
biomedich-166	156	3	357	357	NUM
biomedich-166	156	4	.	.	PUNCT
biomedich-166	157	1	amato	amato	PROPN
biomedich-166	157	2	d.r	d.r	PROPN
biomedich-166	157	3	,	,	PUNCT
biomedich-166	157	4	lim	lim	PROPN
biomedich-166	157	5	p	p	X
biomedich-166	157	6	,	,	PUNCT
biomedich-166	157	7	miotto	miotto	ADJ
biomedich-166	157	8	o	o	NOUN
biomedich-166	157	9	,	,	PUNCT
biomedich-166	157	10	amaratunga	amaratunga	PROPN
biomedich-166	157	11	c	c	X
biomedich-166	157	12	,	,	PUNCT
biomedich-166	157	13	dek	dek	PROPN
biomedich-166	157	14	d	d	PROPN
biomedich-166	157	15	,	,	PUNCT
biomedich-166	157	16	pearson	pearson	PROPN
biomedich-166	157	17	r.d	r.d	PROPN
biomedich-166	157	18	et	et	PROPN
biomedich-166	157	19	al	al	PROPN
biomedich-166	157	20	.	.	PROPN
biomedich-166	157	21	(	(	PUNCT
biomedich-166	157	22	2017	2017	NUM
biomedich-166	157	23	)	)	PUNCT
biomedich-166	157	24	genetic	genetic	ADJ
biomedich-166	157	25	markers	marker	NOUN
biomedich-166	157	26	associated	associate	VERB
biomedich-166	157	27	with	with	ADP
biomedich-166	157	28	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	157	29	–	–	PUNCT
biomedich-166	157	30	piperaquine	piperaquine	ADJ
biomedich-166	157	31	failure	failure	NOUN
biomedich-166	157	32	in	in	ADP
biomedich-166	157	33	plasmodium	plasmodium	NOUN
biomedich-166	157	34	falciparum	falciparum	ADJ
biomedich-166	157	35	malaria	malaria	NOUN
biomedich-166	157	36	in	in	ADP
biomedich-166	157	37	cambodia	cambodia	PROPN
biomedich-166	157	38	:	:	PUNCT
biomedich-166	157	39	a	a	DET
biomedich-166	157	40	genotype	genotype	NOUN
biomedich-166	157	41	-	-	PUNCT
biomedich-166	157	42	phenotype	phenotype	NOUN
biomedich-166	157	43	association	association	NOUN
biomedich-166	157	44	study	study	NOUN
biomedich-166	157	45	.	.	PUNCT
biomedich-166	158	1	lancet	lancet	PROPN
biomedich-166	158	2	infect	infect	PROPN
biomedich-166	158	3	dis	dis	PROPN
biomedich-166	158	4	.	.	PUNCT
biomedich-166	159	1	17	17	NUM
biomedich-166	159	2	,	,	PUNCT
biomedich-166	159	3	164–173	164–173	NUM
biomedich-166	159	4	basco	basco	PROPN
biomedich-166	159	5	,	,	PUNCT
biomedich-166	159	6	l	l	PROPN
biomedich-166	159	7	k	k	X
biomedich-166	159	8	,	,	PUNCT
biomedich-166	159	9	&	&	CCONJ
biomedich-166	159	10	le	le	PROPN
biomedich-166	159	11	bras	bras	PROPN
biomedich-166	159	12	j.	j.	PROPN
biomedich-166	159	13	(	(	PUNCT
biomedich-166	159	14	1993	1993	NUM
biomedich-166	159	15	)	)	PUNCT
biomedich-166	159	16	.	.	PUNCT
biomedich-166	160	1	activity	activity	NOUN
biomedich-166	160	2	in	in	ADP
biomedich-166	160	3	vitro	vitro	X
biomedich-166	160	4	of	of	ADP
biomedich-166	160	5	doxycycline	doxycycline	NOUN
biomedich-166	160	6	against	against	ADP
biomedich-166	160	7	multidrug	multidrug	NOUN
biomedich-166	160	8	-	-	PUNCT
biomedich-166	160	9	resistant	resistant	ADJ
biomedich-166	160	10	plasmodium	plasmodium	NOUN
biomedich-166	160	11	falciparum	falciparum	NOUN
biomedich-166	160	12	.	.	PUNCT
biomedich-166	161	1	transaction	transaction	NOUN
biomedich-166	161	2	of	of	ADP
biomedich-166	161	3	royal	royal	ADJ
biomedich-166	161	4	society	society	NOUN
biomedich-166	161	5	of	of	ADP
biomedich-166	161	6	tropical	tropical	ADJ
biomedich-166	161	7	medicine	medicine	NOUN
biomedich-166	161	8	and	and	CCONJ
biomedich-166	161	9	hygiene	hygiene	NOUN
biomedich-166	161	10	.	.	PUNCT
biomedich-166	162	1	87:469–470	87:469–470	NUM
biomedich-166	163	1	beeson	beeson	PROPN
biomedich-166	163	2	jg	jg	PROPN
biomedich-166	163	3	,	,	PUNCT
biomedich-166	163	4	drew	draw	VERB
biomedich-166	163	5	dr	dr	PROPN
biomedich-166	163	6	,	,	PUNCT
biomedich-166	163	7	boyle	boyle	PROPN
biomedich-166	163	8	mj	mj	PROPN
biomedich-166	163	9	,	,	PUNCT
biomedich-166	163	10	feng	feng	PROPN
biomedich-166	163	11	g	g	PROPN
biomedich-166	163	12	,	,	PUNCT
biomedich-166	163	13	fowkes	fowke	VERB
biomedich-166	163	14	fj	fj	PROPN
biomedich-166	163	15	,	,	PUNCT
biomedich-166	163	16	richards	richards	PROPN
biomedich-166	163	17	js	js	PROPN
biomedich-166	163	18	et	et	PROPN
biomedich-166	163	19	al	al	PROPN
biomedich-166	163	20	.	.	PUNCT
biomedich-166	164	1	(	(	PUNCT
biomedich-166	164	2	2016	2016	NUM
biomedich-166	164	3	)	)	PUNCT
biomedich-166	164	4	merozoite	merozoite	ADJ
biomedich-166	164	5	surface	surface	NOUN
biomedich-166	164	6	proteins	protein	NOUN
biomedich-166	164	7	in	in	ADP
biomedich-166	164	8	red	red	ADJ
biomedich-166	164	9	blood	blood	NOUN
biomedich-166	164	10	cell	cell	NOUN
biomedich-166	164	11	invasion	invasion	NOUN
biomedich-166	164	12	,	,	PUNCT
biomedich-166	164	13	immunity	immunity	NOUN
biomedich-166	164	14	and	and	CCONJ
biomedich-166	164	15	vaccines	vaccine	NOUN
biomedich-166	164	16	against	against	ADP
biomedich-166	164	17	malaria	malaria	NOUN
biomedich-166	164	18	.	.	PUNCT
biomedich-166	165	1	fems	fems	PROPN
biomedich-166	165	2	microbiology	microbiology	NOUN
biomedich-166	165	3	review	review	NOUN
biomedich-166	165	4	.	.	PUNCT
biomedich-166	166	1	40(3):343–372	40(3):343–372	NUM
biomedich-166	166	2	.	.	PUNCT
biomedich-166	167	1	desai	desai	PROPN
biomedich-166	167	2	m	m	PROPN
biomedich-166	167	3	,	,	PUNCT
biomedich-166	167	4	hill	hill	PROPN
biomedich-166	167	5	j	j	PROPN
biomedich-166	167	6	,	,	PUNCT
biomedich-166	167	7	fernandes	fernandes	PROPN
biomedich-166	167	8	s	s	PROPN
biomedich-166	167	9	,	,	PUNCT
biomedich-166	167	10	walker	walker	PROPN
biomedich-166	167	11	p	p	PROPN
biomedich-166	167	12	,	,	PUNCT
biomedich-166	167	13	pell	pell	NOUN
biomedich-166	167	14	c	c	NOUN
biomedich-166	167	15	,	,	PUNCT
biomedich-166	167	16	gutman	gutman	PROPN
biomedich-166	167	17	j	j	PROPN
biomedich-166	167	18	et	et	PROPN
biomedich-166	167	19	al	al	PROPN
biomedich-166	167	20	.	.	PROPN
biomedich-166	168	1	(	(	PUNCT
biomedich-166	168	2	2018	2018	NUM
biomedich-166	168	3	)	)	PUNCT
biomedich-166	168	4	.	.	PUNCT
biomedich-166	169	1	prevention	prevention	NOUN
biomedich-166	169	2	of	of	ADP
biomedich-166	169	3	malaria	malaria	NOUN
biomedich-166	169	4	in	in	ADP
biomedich-166	169	5	pregnancy	pregnancy	NOUN
biomedich-166	169	6	.	.	PUNCT
biomedich-166	170	1	lancet	lancet	VERB
biomedich-166	170	2	infectious	infectious	ADJ
biomedich-166	170	3	disease	disease	NOUN
biomedich-166	170	4	.	.	PUNCT
biomedich-166	171	1	18	18	NUM
biomedich-166	171	2	,	,	PUNCT
biomedich-166	171	3	119–132	119–132	NUM
biomedich-166	171	4	.	.	PUNCT
biomedich-166	172	1	gaillard	gaillard	PROPN
biomedich-166	172	2	t	t	PROPN
biomedich-166	172	3	,	,	PUNCT
biomedich-166	172	4	madamet	madamet	PROPN
biomedich-166	172	5	m	m	PROPN
biomedich-166	172	6	,	,	PUNCT
biomedich-166	172	7	&	&	CCONJ
biomedich-166	172	8	pradines	pradines	PROPN
biomedich-166	172	9	b.	b.	PROPN
biomedich-166	172	10	(	(	PUNCT
biomedich-166	172	11	2015	2015	NUM
biomedich-166	172	12	)	)	PUNCT
biomedich-166	172	13	.	.	PUNCT
biomedich-166	173	1	tetracyclines	tetracycline	NOUN
biomedich-166	173	2	in	in	ADP
biomedich-166	173	3	malaria	malaria	NOUN
biomedich-166	173	4	.	.	PUNCT
biomedich-166	174	1	malarial	malarial	ADJ
biomedich-166	174	2	journal	journal	NOUN
biomedich-166	174	3	.	.	PUNCT
biomedich-166	175	1	14	14	NUM
biomedich-166	175	2	,	,	PUNCT
biomedich-166	175	3	445	445	NUM
biomedich-166	175	4	;	;	PUNCT
biomedich-166	175	5	1	1	NUM
biomedich-166	175	6	-	-	SYM
biomedich-166	175	7	10	10	NUM
biomedich-166	175	8	.	.	PUNCT
biomedich-166	176	1	griffith	griffith	PROPN
biomedich-166	176	2	ks	ks	PROPN
biomedich-166	176	3	,	,	PUNCT
biomedich-166	176	4	lewis	lewis	PROPN
biomedich-166	176	5	ls	ls	PROPN
biomedich-166	176	6	,	,	PUNCT
biomedich-166	176	7	mali	mali	PROPN
biomedich-166	176	8	s	s	PROPN
biomedich-166	176	9	,	,	PUNCT
biomedich-166	176	10	&	&	CCONJ
biomedich-166	176	11	parise	parise	PROPN
biomedich-166	176	12	me	i	PRON
biomedich-166	176	13	.	.	PUNCT
biomedich-166	177	1	(	(	PUNCT
biomedich-166	177	2	2007	2007	NUM
biomedich-166	177	3	)	)	PUNCT
biomedich-166	177	4	treatment	treatment	NOUN
biomedich-166	177	5	of	of	ADP
biomedich-166	177	6	malaria	malaria	NOUN
biomedich-166	177	7	in	in	ADP
biomedich-166	177	8	the	the	DET
biomedich-166	177	9	united	united	PROPN
biomedich-166	177	10	states	states	PROPN
biomedich-166	177	11	:	:	PUNCT
biomedich-166	177	12	a	a	DET
biomedich-166	177	13	systematic	systematic	ADJ
biomedich-166	177	14	review	review	NOUN
biomedich-166	177	15	.	.	PUNCT
biomedich-166	178	1	journal	journal	PROPN
biomedich-166	178	2	of	of	ADP
biomedich-166	178	3	american	american	PROPN
biomedich-166	178	4	medical	medical	PROPN
biomedich-166	178	5	association	association	PROPN
biomedich-166	178	6	.	.	PUNCT
biomedich-166	179	1	297:2264–2277	297:2264–2277	NUM
biomedich-166	179	2	hiben	hiben	PROPN
biomedich-166	179	3	mg	mg	PROPN
biomedich-166	179	4	,	,	PUNCT
biomedich-166	179	5	sibhat	sibhat	DET
biomedich-166	179	6	gg	gg	PROPN
biomedich-166	179	7	,	,	PUNCT
biomedich-166	179	8	fanta	fanta	PROPN
biomedich-166	179	9	bs	bs	PROPN
biomedich-166	179	10	,	,	PUNCT
biomedich-166	179	11	gebrezgi	gebrezgi	ADJ
biomedich-166	179	12	hd	hd	NOUN
biomedich-166	179	13	,	,	PUNCT
biomedich-166	179	14	&	&	CCONJ
biomedich-166	179	15	tesema	tesema	PROPN
biomedich-166	179	16	sb	sb	PROPN
biomedich-166	179	17	(	(	PUNCT
biomedich-166	179	18	2016	2016	NUM
biomedich-166	179	19	)	)	PUNCT
biomedich-166	179	20	.	.	PUNCT
biomedich-166	180	1	evaluation	evaluation	NOUN
biomedich-166	180	2	of	of	ADP
biomedich-166	180	3	senna	senna	PROPN
biomedich-166	180	4	singueana	singueana	PROPN
biomedich-166	180	5	leaf	leaf	PROPN
biomedich-166	180	6	extract	extract	NOUN
biomedich-166	180	7	as	as	ADP
biomedich-166	180	8	an	an	DET
biomedich-166	180	9	alternative	alternative	NOUN
biomedich-166	180	10	or	or	CCONJ
biomedich-166	180	11	adjuvant	adjuvant	ADJ
biomedich-166	180	12	therapy	therapy	NOUN
biomedich-166	180	13	for	for	ADP
biomedich-166	180	14	malaria	malaria	NOUN
biomedich-166	180	15	.	.	PUNCT
biomedich-166	181	1	journal	journal	NOUN
biomedich-166	181	2	of	of	ADP
biomedich-166	181	3	traditional	traditional	ADJ
biomedich-166	181	4	and	and	CCONJ
biomedich-166	181	5	complimentary	complimentary	ADJ
biomedich-166	181	6	medicine	medicine	NOUN
biomedich-166	181	7	.	.	PUNCT
biomedich-166	182	1	6:112	6:112	ADJ
biomedich-166	182	2	-	-	PUNCT
biomedich-166	182	3	117	117	NUM
biomedich-166	182	4	joseph	joseph	PROPN
biomedich-166	182	5	ao	ao	PROPN
biomedich-166	182	6	,	,	PUNCT
biomedich-166	182	7	&	&	CCONJ
biomedich-166	182	8	samson	samson	PROPN
biomedich-166	182	9	ot	ot	PROPN
biomedich-166	182	10	(	(	PUNCT
biomedich-166	182	11	2020	2020	NUM
biomedich-166	182	12	)	)	PUNCT
biomedich-166	182	13	antiplasmodial	antiplasmodial	ADJ
biomedich-166	182	14	efficacy	efficacy	NOUN
biomedich-166	182	15	of	of	ADP
biomedich-166	182	16	anacardium	anacardium	PROPN
biomedich-166	182	17	occidentale	occidentale	PROPN
biomedich-166	182	18	in	in	ADP
biomedich-166	182	19	albino	albino	NOUN
biomedich-166	182	20	mice	mouse	NOUN
biomedich-166	182	21	infected	infect	VERB
biomedich-166	182	22	with	with	ADP
biomedich-166	182	23	plasmodium	plasmodium	NOUN
biomedich-166	182	24	berghei	berghei	PROPN
biomedich-166	182	25	.	.	PUNCT
biomedich-166	183	1	journal	journal	PROPN
biomedich-166	183	2	of	of	ADP
biomedich-166	183	3	family	family	NOUN
biomedich-166	183	4	medicine	medicine	NOUN
biomedich-166	183	5	and	and	CCONJ
biomedich-166	183	6	disease	disease	NOUN
biomedich-166	183	7	prevention	prevention	NOUN
biomedich-166	183	8	.	.	PUNCT
biomedich-166	184	1	6:123;1	6:123;1	NUM
biomedich-166	184	2	-	-	SYM
biomedich-166	184	3	6	6	NUM
biomedich-166	184	4	kakuru	kakuru	ADV
biomedich-166	184	5	a	a	NOUN
biomedich-166	184	6	,	,	PUNCT
biomedich-166	184	7	jagannathan	jagannathan	ADP
biomedich-166	184	8	p	p	NOUN
biomedich-166	184	9	,	,	PUNCT
biomedich-166	184	10	muhindo	muhindo	NOUN
biomedich-166	184	11	m.k	m.k	PROPN
biomedich-166	184	12	,	,	PUNCT
biomedich-166	184	13	natureeba	natureeba	NOUN
biomedich-166	184	14	p	p	NOUN
biomedich-166	184	15	,	,	PUNCT
biomedich-166	184	16	awori	awori	ADJ
biomedich-166	184	17	,	,	PUNCT
biomedich-166	184	18	p	p	X
biomedich-166	184	19	,	,	PUNCT
biomedich-166	184	20	nakalembe	nakalembe	NOUN
biomedich-166	184	21	m	m	PROPN
biomedich-166	184	22	,	,	PUNCT
biomedich-166	184	23	et	et	PROPN
biomedich-166	184	24	al	al	PROPN
biomedich-166	184	25	.	.	PROPN
biomedich-166	184	26	,	,	PUNCT
biomedich-166	184	27	(	(	PUNCT
biomedich-166	184	28	2016	2016	NUM
biomedich-166	184	29	)	)	PUNCT
biomedich-166	184	30	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	184	31	-	-	PUNCT
biomedich-166	184	32	piperaquine	piperaquine	NOUN
biomedich-166	184	33	for	for	ADP
biomedich-166	184	34	the	the	DET
biomedich-166	184	35	prevention	prevention	NOUN
biomedich-166	184	36	of	of	ADP
biomedich-166	184	37	malaria	malaria	NOUN
biomedich-166	184	38	in	in	ADP
biomedich-166	184	39	pregnancy	pregnancy	NOUN
biomedich-166	184	40	.	.	PUNCT
biomedich-166	185	1	new	new	PROPN
biomedich-166	185	2	england	england	PROPN
biomedich-166	185	3	journal	journal	PROPN
biomedich-166	185	4	of	of	ADP
biomedich-166	185	5	medicine	medicine	NOUN
biomedich-166	185	6	.	.	PUNCT
biomedich-166	186	1	374	374	NUM
biomedich-166	186	2	,	,	PUNCT
biomedich-166	186	3	928–939	928–939	NUM
biomedich-166	186	4	.	.	PUNCT
biomedich-166	187	1	knight	knight	PROPN
biomedich-166	187	2	dj	dj	PROPN
biomedich-166	187	3	,	,	PUNCT
biomedich-166	187	4	&	&	CCONJ
biomedich-166	187	5	peters	peters	PROPN
biomedich-166	187	6	w.	w.	PROPN
biomedich-166	187	7	(	(	PUNCT
biomedich-166	187	8	1980	1980	NUM
biomedich-166	187	9	)	)	PUNCT
biomedich-166	187	10	.	.	PUNCT
biomedich-166	188	1	the	the	DET
biomedich-166	188	2	antimalarial	antimalarial	ADJ
biomedich-166	188	3	action	action	NOUN
biomedich-166	188	4	of	of	ADP
biomedich-166	188	5	nbenzyl	nbenzyl	NOUN
biomedich-166	188	6	oxydihydrotriazines	oxydihydrotriazine	NOUN
biomedich-166	188	7	and	and	CCONJ
biomedich-166	188	8	the	the	DET
biomedich-166	188	9	studies	study	NOUN
biomedich-166	188	10	on	on	ADP
biomedich-166	188	11	its	its	PRON
biomedich-166	188	12	mode	mode	NOUN
biomedich-166	188	13	of	of	ADP
biomedich-166	188	14	action	action	NOUN
biomedich-166	188	15	.	.	PUNCT
biomedich-166	189	1	annals	annal	NOUN
biomedich-166	189	2	of	of	ADP
biomedich-166	189	3	tropical	tropical	ADJ
biomedich-166	189	4	medicine	medicine	NOUN
biomedich-166	189	5	and	and	CCONJ
biomedich-166	189	6	parasitology	parasitology	NOUN
biomedich-166	189	7	.	.	PUNCT
biomedich-166	190	1	74	74	NUM
biomedich-166	190	2	:	:	PUNCT
biomedich-166	190	3	393	393	NUM
biomedich-166	190	4	-	-	SYM
biomedich-166	190	5	404	404	NUM
biomedich-166	190	6	.	.	PUNCT
biomedich-166	191	1	leang	leang	PROPN
biomedich-166	191	2	r	r	PROPN
biomedich-166	191	3	,	,	PUNCT
biomedich-166	191	4	barrette	barrette	PROPN
biomedich-166	191	5	a	a	DET
biomedich-166	191	6	,	,	PUNCT
biomedich-166	191	7	bouth	bouth	PROPN
biomedich-166	191	8	dm	dm	PROPN
biomedich-166	191	9	,	,	PUNCT
biomedich-166	191	10	menard	menard	PROPN
biomedich-166	191	11	d	d	PROPN
biomedich-166	191	12	,	,	PUNCT
biomedich-166	191	13	abdur	abdur	PROPN
biomedich-166	191	14	r	r	PROPN
biomedich-166	191	15	,	,	PUNCT
biomedich-166	191	16	duong	duong	PROPN
biomedich-166	191	17	s	s	PROPN
biomedich-166	191	18	et	et	NOUN
biomedich-166	191	19	al	al	PROPN
biomedich-166	191	20	.	.	PROPN
biomedich-166	191	21	,	,	PUNCT
biomedich-166	191	22	(	(	PUNCT
biomedich-166	191	23	2013	2013	NUM
biomedich-166	191	24	)	)	PUNCT
biomedich-166	191	25	.	.	PUNCT
biomedich-166	192	1	efficacy	efficacy	NOUN
biomedich-166	192	2	of	of	ADP
biomedich-166	192	3	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	192	4	-	-	PUNCT
biomedich-166	192	5	piperaquine	piperaquine	NOUN
biomedich-166	192	6	for	for	ADP
biomedich-166	192	7	treatment	treatment	NOUN
biomedich-166	192	8	of	of	ADP
biomedich-166	192	9	uncomplicated	uncomplicated	ADJ
biomedich-166	192	10	plasmodium	plasmodium	NOUN
biomedich-166	192	11	falciparum	falciparum	NOUN
biomedich-166	192	12	and	and	CCONJ
biomedich-166	192	13	plasmodium	plasmodium	NOUN
biomedich-166	192	14	vivax	vivax	NOUN
biomedich-166	192	15	in	in	ADP
biomedich-166	192	16	cambodia	cambodia	PROPN
biomedich-166	192	17	,	,	PUNCT
biomedich-166	192	18	2008	2008	NUM
biomedich-166	192	19	to	to	ADP
biomedich-166	192	20	2010	2010	NUM
biomedich-166	192	21	.	.	PUNCT
biomedich-166	193	1	antimicrobial	antimicrobial	ADJ
biomedich-166	193	2	agents	agent	NOUN
biomedich-166	193	3	chemotherapy	chemotherapy	NOUN
biomedich-166	193	4	.	.	PUNCT
biomedich-166	194	1	57	57	NUM
biomedich-166	194	2	,	,	PUNCT
biomedich-166	194	3	818–826	818–826	NUM
biomedich-166	194	4	.	.	PUNCT
biomedich-166	195	1	mcevoy	mcevoy	PROPN
biomedich-166	195	2	g.	g.	PROPN
biomedich-166	195	3	(	(	PUNCT
biomedich-166	195	4	2008	2008	NUM
biomedich-166	195	5	)	)	PUNCT
biomedich-166	195	6	.	.	PUNCT
biomedich-166	196	1	ahfs	ahfs	PROPN
biomedich-166	196	2	drug	drug	NOUN
biomedich-166	196	3	information	information	NOUN
biomedich-166	196	4	.	.	PUNCT
biomedich-166	197	1	bethesda	bethesda	PROPN
biomedich-166	197	2	,	,	PUNCT
biomedich-166	197	3	md	md	PROPN
biomedich-166	197	4	:	:	PUNCT
biomedich-166	197	5	american	american	ADJ
biomedich-166	197	6	society	society	NOUN
biomedich-166	197	7	of	of	ADP
biomedich-166	197	8	health	health	NOUN
biomedich-166	197	9	-	-	PUNCT
biomedich-166	197	10	system	system	NOUN
biomedich-166	197	11	pharmacists	pharmacist	NOUN
biomedich-166	197	12	,	,	PUNCT
biomedich-166	197	13	inc	inc	PROPN
biomedich-166	197	14	;	;	PUNCT
biomedich-166	197	15	2008	2008	NUM
biomedich-166	197	16	.	.	PUNCT
biomedich-166	198	1	mekonnen	mekonnen	NOUN
biomedich-166	198	2	lb	lb	NOUN
biomedich-166	198	3	.	.	PUNCT
biomedich-166	198	4	(	(	PUNCT
biomedich-166	198	5	2015	2015	NUM
biomedich-166	198	6	)	)	PUNCT
biomedich-166	198	7	.	.	PUNCT
biomedich-166	199	1	in	in	ADP
biomedich-166	199	2	vivo	vivo	ADJ
biomedich-166	199	3	antimalarial	antimalarial	ADJ
biomedich-166	199	4	activity	activity	NOUN
biomedich-166	199	5	of	of	ADP
biomedich-166	199	6	the	the	DET
biomedich-166	199	7	crude	crude	ADJ
biomedich-166	199	8	root	root	NOUN
biomedich-166	199	9	and	and	CCONJ
biomedich-166	199	10	fruit	fruit	NOUN
biomedich-166	199	11	extracts	extract	NOUN
biomedich-166	199	12	of	of	ADP
biomedich-166	199	13	croton	croton	PROPN
biomedich-166	199	14	macrostachyus	macrostachyus	PROPN
biomedich-166	199	15	(	(	PUNCT
biomedich-166	199	16	euphorbiaceae	euphorbiaceae	PROPN
biomedich-166	199	17	)	)	PUNCT
biomedich-166	199	18	against	against	ADP
biomedich-166	199	19	plasmodium	plasmodium	NOUN
biomedich-166	199	20	berghei	berghei	NOUN
biomedich-166	199	21	in	in	ADP
biomedich-166	199	22	mice	mouse	NOUN
biomedich-166	199	23	.	.	PUNCT
biomedich-166	200	1	journal	journal	NOUN
biomedich-166	200	2	of	of	ADP
biomedich-166	200	3	traditional	traditional	ADJ
biomedich-166	200	4	and	and	CCONJ
biomedich-166	200	5	complimentary	complimentary	ADJ
biomedich-166	200	6	medicine	medicine	NOUN
biomedich-166	200	7	.	.	PUNCT
biomedich-166	201	1	5:168e173	5:168e173	PROPN
biomedich-166	201	2	meshnick	meshnick	PROPN
biomedich-166	201	3	sr	sr	PROPN
biomedich-166	201	4	.	.	PUNCT
biomedich-166	202	1	(	(	PUNCT
biomedich-166	202	2	1994	1994	NUM
biomedich-166	202	3	)	)	PUNCT
biomedich-166	202	4	the	the	DET
biomedich-166	202	5	mode	mode	NOUN
biomedich-166	202	6	of	of	ADP
biomedich-166	202	7	action	action	NOUN
biomedich-166	202	8	of	of	ADP
biomedich-166	202	9	antimalarial	antimalarial	ADJ
biomedich-166	202	10	endoperoxides	endoperoxide	NOUN
biomedich-166	202	11	.	.	PUNCT
biomedich-166	203	1	transaction	transaction	NOUN
biomedich-166	203	2	of	of	ADP
biomedich-166	203	3	royal	royal	ADJ
biomedich-166	203	4	society	society	NOUN
biomedich-166	203	5	of	of	ADP
biomedich-166	203	6	tropical	tropical	ADJ
biomedich-166	203	7	medicine	medicine	NOUN
biomedich-166	203	8	and	and	CCONJ
biomedich-166	203	9	hygiene	hygiene	NOUN
biomedich-166	203	10	88:131	88:131	NUM
biomedich-166	203	11	-	-	SYM
biomedich-166	203	12	2	2	NUM
biomedich-166	203	13	.	.	PUNCT
biomedich-166	203	14	nardos	nardos	PROPN
biomedich-166	203	15	a	a	PRON
biomedich-166	203	16	,	,	PUNCT
biomedich-166	203	17	&	&	CCONJ
biomedich-166	203	18	makonnen	makonnen	PROPN
biomedich-166	203	19	e	e	PROPN
biomedich-166	203	20	(	(	PUNCT
biomedich-166	203	21	2017	2017	NUM
biomedich-166	203	22	)	)	PUNCT
biomedich-166	203	23	.	.	PUNCT
biomedich-166	204	1	in	in	ADP
biomedich-166	204	2	vivo	vivo	ADJ
biomedich-166	204	3	antiplasmodial	antiplasmodial	ADJ
biomedich-166	204	4	activity	activity	NOUN
biomedich-166	204	5	and	and	CCONJ
biomedich-166	204	6	toxicological	toxicological	ADJ
biomedich-166	204	7	assessment	assessment	NOUN
biomedich-166	204	8	of	of	ADP
biomedich-166	204	9	hydroethanolic	hydroethanolic	ADJ
biomedich-166	204	10	crude	crude	ADJ
biomedich-166	204	11	extract	extract	NOUN
biomedich-166	204	12	of	of	ADP
biomedich-166	204	13	ajuga	ajuga	PROPN
biomedich-166	204	14	remota	remota	PROPN
biomedich-166	204	15	.	.	PUNCT
biomedich-166	205	1	malarial	malarial	ADJ
biomedich-166	205	2	journal	journal	PROPN
biomedich-166	205	3	.	.	PUNCT
biomedich-166	206	1	16:25	16:25	NUM
biomedich-166	206	2	;	;	PUNCT
biomedich-166	206	3	1	1	NUM
biomedich-166	206	4	-	-	SYM
biomedich-166	206	5	8	8	NUM
biomedich-166	206	6	nosten	nosten	NOUN
biomedich-166	206	7	f	f	PROPN
biomedich-166	206	8	,	,	PUNCT
biomedich-166	206	9	&	&	CCONJ
biomedich-166	206	10	white	white	PROPN
biomedich-166	206	11	nj	nj	PROPN
biomedich-166	206	12	.	.	PUNCT
biomedich-166	207	1	(	(	PUNCT
biomedich-166	207	2	2007	2007	NUM
biomedich-166	207	3	)	)	PUNCT
biomedich-166	207	4	artemisinin	artemisinin	NOUN
biomedich-166	207	5	-	-	PUNCT
biomedich-166	207	6	based	base	VERB
biomedich-166	207	7	combination	combination	NOUN
biomedich-166	207	8	treatment	treatment	NOUN
biomedich-166	207	9	of	of	ADP
biomedich-166	207	10	falciparum	falciparum	ADJ
biomedich-166	207	11	malaria	malaria	NOUN
biomedich-166	207	12	.	.	PUNCT
biomedich-166	208	1	american	american	ADJ
biomedich-166	208	2	journal	journal	PROPN
biomedich-166	208	3	of	of	ADP
biomedich-166	208	4	tropical	tropical	ADJ
biomedich-166	208	5	medicine	medicine	NOUN
biomedich-166	208	6	and	and	CCONJ
biomedich-166	208	7	hygiene	hygiene	NOUN
biomedich-166	208	8	.	.	PUNCT
biomedich-166	209	1	77	77	NUM
biomedich-166	209	2	,	,	PUNCT
biomedich-166	209	3	181–192	181–192	NUM
biomedich-166	209	4	140	140	NUM
biomedich-166	209	5	biology	biology	NOUN
biomedich-166	209	6	,	,	PUNCT
biomedich-166	209	7	medicine	medicine	NOUN
biomedich-166	209	8	,	,	PUNCT
biomedich-166	209	9	&	&	CCONJ
biomedich-166	209	10	natural	natural	ADJ
biomedich-166	209	11	product	product	NOUN
biomedich-166	209	12	chemistry	chemistry	NOUN
biomedich-166	209	13	10	10	NUM
biomedich-166	209	14	(	(	PUNCT
biomedich-166	209	15	2	2	NUM
biomedich-166	209	16	)	)	PUNCT
biomedich-166	209	17	,	,	PUNCT
biomedich-166	209	18	2021	2021	NUM
biomedich-166	209	19	:	:	PUNCT
biomedich-166	209	20	135	135	NUM
biomedich-166	209	21	-	-	SYM
biomedich-166	209	22	140	140	NUM
biomedich-166	209	23	peters	peters	PROPN
biomedich-166	209	24	w.	w.	NOUN
biomedich-166	209	25	(	(	PUNCT
biomedich-166	209	26	1967	1967	NUM
biomedich-166	209	27	)	)	PUNCT
biomedich-166	209	28	.	.	PUNCT
biomedich-166	210	1	rational	rational	ADJ
biomedich-166	210	2	methods	method	NOUN
biomedich-166	210	3	in	in	ADP
biomedich-166	210	4	the	the	DET
biomedich-166	210	5	search	search	NOUN
biomedich-166	210	6	for	for	ADP
biomedich-166	210	7	antimalarial	antimalarial	ADJ
biomedich-166	210	8	drugs	drug	NOUN
biomedich-166	210	9	.	.	PUNCT
biomedich-166	211	1	transaction	transaction	NOUN
biomedich-166	211	2	of	of	ADP
biomedich-166	211	3	royal	royal	ADJ
biomedich-166	211	4	society	society	NOUN
biomedich-166	211	5	of	of	ADP
biomedich-166	211	6	tropical	tropical	ADJ
biomedich-166	211	7	medicine	medicine	NOUN
biomedich-166	211	8	and	and	CCONJ
biomedich-166	211	9	hygiene	hygiene	NOUN
biomedich-166	211	10	.	.	PUNCT
biomedich-166	212	1	61	61	NUM
biomedich-166	212	2	:	:	SYM
biomedich-166	212	3	400	400	NUM
biomedich-166	212	4	-	-	SYM
biomedich-166	212	5	410	410	NUM
biomedich-166	212	6	.	.	PUNCT
biomedich-166	213	1	prapunwattana	prapunwattana	PROPN
biomedich-166	213	2	p	p	X
biomedich-166	213	3	,	,	PUNCT
biomedich-166	213	4	o’sullivan	o’sullivan	PROPN
biomedich-166	213	5	wj	wj	PROPN
biomedich-166	213	6	,	,	PUNCT
biomedich-166	213	7	&	&	CCONJ
biomedich-166	213	8	yuthavong	yuthavong	PROPN
biomedich-166	213	9	y.	y.	PROPN
biomedich-166	213	10	(	(	PUNCT
biomedich-166	213	11	1988	1988	NUM
biomedich-166	213	12	)	)	PUNCT
biomedich-166	213	13	.	.	PUNCT
biomedich-166	214	1	depression	depression	NOUN
biomedich-166	214	2	of	of	ADP
biomedich-166	214	3	plasmodium	plasmodium	NOUN
biomedich-166	214	4	falciparum	falciparum	ADJ
biomedich-166	214	5	dihydroorotate	dihydroorotate	NOUN
biomedich-166	214	6	dehydrogenase	dehydrogenase	NOUN
biomedich-166	214	7	activity	activity	NOUN
biomedich-166	214	8	in	in	ADP
biomedich-166	214	9	in	in	ADP
biomedich-166	214	10	vitroculture	vitroculture	NOUN
biomedich-166	214	11	by	by	ADP
biomedich-166	214	12	tetracycline	tetracycline	NOUN
biomedich-166	214	13	.	.	PUNCT
biomedich-166	215	1	molecular	molecular	ADJ
biomedich-166	215	2	and	and	CCONJ
biomedich-166	215	3	biochemical	biochemical	ADJ
biomedich-166	215	4	parasitology	parasitology	NOUN
biomedich-166	215	5	.	.	PUNCT
biomedich-166	216	1	27:119–24	27:119–24	PROPN
biomedich-166	216	2	.	.	PUNCT
biomedich-166	217	1	ryley	ryley	PROPN
biomedich-166	217	2	jf	jf	PROPN
biomedich-166	217	3	,	,	PUNCT
biomedich-166	217	4	&	&	CCONJ
biomedich-166	217	5	peters	peters	PROPN
biomedich-166	217	6	w.	w.	PROPN
biomedich-166	217	7	(	(	PUNCT
biomedich-166	217	8	1970	1970	NUM
biomedich-166	217	9	)	)	PUNCT
biomedich-166	217	10	the	the	DET
biomedich-166	217	11	antimalarial	antimalarial	ADJ
biomedich-166	217	12	activity	activity	NOUN
biomedich-166	217	13	of	of	ADP
biomedich-166	217	14	some	some	DET
biomedich-166	217	15	quinolone	quinolone	ADJ
biomedich-166	217	16	esters	ester	NOUN
biomedich-166	217	17	.	.	PUNCT
biomedich-166	218	1	annals	annal	NOUN
biomedich-166	218	2	of	of	ADP
biomedich-166	218	3	tropical	tropical	ADJ
biomedich-166	218	4	medicine	medicine	NOUN
biomedich-166	218	5	and	and	CCONJ
biomedich-166	218	6	parasitology	parasitology	NOUN
biomedich-166	218	7	.	.	PUNCT
biomedich-166	219	1	84	84	NUM
biomedich-166	219	2	:	:	PUNCT
biomedich-166	220	1	209	209	NUM
biomedich-166	220	2	-	-	SYM
biomedich-166	220	3	222	222	NUM
biomedich-166	220	4	.	.	PUNCT
biomedich-166	220	5	satish	satish	PROPN
biomedich-166	220	6	pvv	pvv	PROPN
biomedich-166	220	7	,	,	PUNCT
biomedich-166	220	8	kumari	kumari	PROPN
biomedich-166	220	9	ds	ds	PROPN
biomedich-166	220	10	,	,	PUNCT
biomedich-166	220	11	&	&	CCONJ
biomedich-166	220	12	sunita	sunita	PROPN
biomedich-166	220	13	k	k	PROPN
biomedich-166	220	14	,	,	PUNCT
biomedich-166	220	15	(	(	PUNCT
biomedich-166	220	16	2017	2017	NUM
biomedich-166	220	17	)	)	PUNCT
biomedich-166	220	18	antiplasmodial	antiplasmodial	ADJ
biomedich-166	220	19	efficacy	efficacy	NOUN
biomedich-166	220	20	of	of	ADP
biomedich-166	220	21	calotropis	calotropis	ADJ
biomedich-166	220	22	gigantean	gigantean	NOUN
biomedich-166	220	23	(	(	PUNCT
biomedich-166	220	24	l.	l.	PROPN
biomedich-166	220	25	)	)	PUNCT
biomedich-166	220	26	against	against	ADP
biomedich-166	220	27	plasmodium	plasmodium	NOUN
biomedich-166	220	28	falciparum	falciparum	NOUN
biomedich-166	220	29	(	(	PUNCT
biomedich-166	220	30	3d7	3d7	NUM
biomedich-166	220	31	strain	strain	NOUN
biomedich-166	220	32	)	)	PUNCT
biomedich-166	220	33	and	and	CCONJ
biomedich-166	220	34	plasmodium	plasmodium	NOUN
biomedich-166	220	35	berghei	berghei	PROPN
biomedich-166	220	36	(	(	PUNCT
biomedich-166	220	37	anka	anka	PROPN
biomedich-166	220	38	)	)	PUNCT
biomedich-166	220	39	.	.	PUNCT
biomedich-166	221	1	journal	journal	PROPN
biomedich-166	221	2	of	of	ADP
biomedich-166	221	3	vector	vector	NOUN
biomedich-166	221	4	borne	borne	NOUN
biomedich-166	221	5	disease	disease	NOUN
biomedich-166	221	6	.	.	PUNCT
biomedich-166	222	1	54(3):215	54(3):215	NUM
biomedich-166	222	2	-	-	SYM
biomedich-166	222	3	225	225	NUM
biomedich-166	222	4	saunders	saunder	NOUN
biomedich-166	222	5	d.	d.	PROPN
biomedich-166	222	6	l	l	PROPN
biomedich-166	222	7	,	,	PUNCT
biomedich-166	222	8	vanachayangkul	vanachayangkul	NOUN
biomedich-166	222	9	p	p	NOUN
biomedich-166	222	10	,	,	PUNCT
biomedich-166	222	11	&	&	CCONJ
biomedich-166	222	12	lon	lon	PROPN
biomedich-166	222	13	c.	c.	PROPN
biomedich-166	222	14	(	(	PUNCT
biomedich-166	222	15	2014	2014	NUM
biomedich-166	222	16	)	)	PUNCT
biomedich-166	222	17	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	222	18	–	–	PUNCT
biomedich-166	222	19	piperaquine	piperaquine	ADJ
biomedich-166	222	20	failure	failure	NOUN
biomedich-166	222	21	in	in	ADP
biomedich-166	222	22	cambodia	cambodia	PROPN
biomedich-166	222	23	.	.	PUNCT
biomedich-166	223	1	new	new	PROPN
biomedich-166	223	2	england	england	PROPN
biomedich-166	223	3	journal	journal	PROPN
biomedich-166	223	4	of	of	ADP
biomedich-166	223	5	medicine	medicine	NOUN
biomedich-166	223	6	.	.	PUNCT
biomedich-166	224	1	371	371	NUM
biomedich-166	224	2	,	,	PUNCT
biomedich-166	224	3	484–485	484–485	NUM
biomedich-166	224	4	somsak	somsak	NOUN
biomedich-166	224	5	v	v	NOUN
biomedich-166	224	6	,	,	PUNCT
biomedich-166	224	7	damkaew	damkaew	VERB
biomedich-166	224	8	a	a	PRON
biomedich-166	224	9	,	,	PUNCT
biomedich-166	224	10	&	&	CCONJ
biomedich-166	224	11	onrak	onrak	PROPN
biomedich-166	225	1	p.	p.	PROPN
biomedich-166	225	2	(	(	PUNCT
biomedich-166	225	3	2018	2018	NUM
biomedich-166	225	4	)	)	PUNCT
biomedich-166	225	5	antimalarial	antimalarial	ADJ
biomedich-166	225	6	activity	activity	NOUN
biomedich-166	225	7	of	of	ADP
biomedich-166	225	8	kaempferol	kaempferol	NOUN
biomedich-166	225	9	and	and	CCONJ
biomedich-166	225	10	its	its	PRON
biomedich-166	225	11	combination	combination	NOUN
biomedich-166	225	12	with	with	ADP
biomedich-166	225	13	chloroquine	chloroquine	NOUN
biomedich-166	225	14	in	in	ADP
biomedich-166	225	15	plasmodium	plasmodium	NOUN
biomedich-166	225	16	berghei	berghei	NOUN
biomedich-166	225	17	infection	infection	NOUN
biomedich-166	225	18	in	in	ADP
biomedich-166	225	19	mice	mouse	NOUN
biomedich-166	225	20	.	.	PUNCT
biomedich-166	226	1	journal	journal	PROPN
biomedich-166	226	2	of	of	ADP
biomedich-166	226	3	pathology	pathology	PROPN
biomedich-166	226	4	.	.	PUNCT
biomedich-166	227	1	2018:1	2018:1	NUM
biomedich-166	227	2	-	-	SYM
biomedich-166	227	3	7	7	NUM
biomedich-166	227	4	.	.	PUNCT
biomedich-166	227	5	tan	tan	PROPN
biomedich-166	227	6	kr	kr	PROPN
biomedich-166	227	7	,	,	PUNCT
biomedich-166	227	8	magill	magill	PROPN
biomedich-166	227	9	aj	aj	PROPN
biomedich-166	227	10	,	,	PUNCT
biomedich-166	227	11	parise	parise	PROPN
biomedich-166	227	12	me	i	PRON
biomedich-166	227	13	,	,	PUNCT
biomedich-166	227	14	&	&	CCONJ
biomedich-166	227	15	arguin	arguin	NOUN
biomedich-166	227	16	pm	pm	PROPN
biomedich-166	227	17	,	,	PUNCT
biomedich-166	227	18	(	(	PUNCT
biomedich-166	227	19	2011	2011	NUM
biomedich-166	227	20	)	)	PUNCT
biomedich-166	227	21	.	.	PUNCT
biomedich-166	228	1	doxycycline	doxycycline	NOUN
biomedich-166	228	2	for	for	ADP
biomedich-166	228	3	malaria	malaria	NOUN
biomedich-166	228	4	chemoprophylaxis	chemoprophylaxis	NOUN
biomedich-166	228	5	and	and	CCONJ
biomedich-166	228	6	treatment	treatment	NOUN
biomedich-166	228	7	:	:	PUNCT
biomedich-166	228	8	report	report	NOUN
biomedich-166	228	9	from	from	ADP
biomedich-166	228	10	the	the	DET
biomedich-166	228	11	cdc	cdc	PROPN
biomedich-166	228	12	expert	expert	NOUN
biomedich-166	228	13	meeting	meeting	NOUN
biomedich-166	228	14	on	on	ADP
biomedich-166	228	15	malaria	malaria	NOUN
biomedich-166	228	16	chemoprophylaxis	chemoprophylaxis	NOUN
biomedich-166	228	17	,	,	PUNCT
biomedich-166	228	18	hygiene	hygiene	NOUN
biomedich-166	228	19	.	.	PUNCT
biomedich-166	229	1	5	5	NUM
biomedich-166	229	2	;	;	PUNCT
biomedich-166	229	3	84(4	84(4	NUM
biomedich-166	229	4	):	):	PUNCT
biomedich-166	229	5	517–531	517–531	NUM
biomedich-166	229	6	.	.	PUNCT
biomedich-166	230	1	tärning	tärne	VERB
biomedich-166	230	2	j.	j.	PROPN
biomedich-166	230	3	piperaquine	piperaquine	PROPN
biomedich-166	230	4	,	,	PUNCT
biomedich-166	230	5	bioanalysis	bioanalysis	NOUN
biomedich-166	230	6	(	(	PUNCT
biomedich-166	230	7	2007	2007	NUM
biomedich-166	230	8	)	)	PUNCT
biomedich-166	230	9	drug	drug	NOUN
biomedich-166	230	10	metabolism	metabolism	NOUN
biomedich-166	230	11	and	and	CCONJ
biomedich-166	230	12	pharmacokinetics	pharmacokinetic	NOUN
biomedich-166	230	13	.	.	PUNCT
biomedich-166	231	1	göteborg	göteborg	PROPN
biomedich-166	231	2	,	,	PUNCT
biomedich-166	231	3	sweden	sweden	PROPN
biomedich-166	231	4	:	:	PUNCT
biomedich-166	231	5	institute	institute	NOUN
biomedich-166	231	6	of	of	ADP
biomedich-166	231	7	neuroscience	neuroscience	NOUN
biomedich-166	231	8	and	and	CCONJ
biomedich-166	231	9	physiology	physiology	NOUN
biomedich-166	231	10	,	,	PUNCT
biomedich-166	231	11	department	department	NOUN
biomedich-166	231	12	of	of	ADP
biomedich-166	231	13	pharmacology	pharmacology	NOUN
biomedich-166	231	14	,	,	PUNCT
biomedich-166	231	15	the	the	DET
biomedich-166	231	16	sahlgrenska	sahlgrenska	PROPN
biomedich-166	231	17	academy	academy	PROPN
biomedich-166	231	18	at	at	ADP
biomedich-166	231	19	göteborg	göteborg	PROPN
biomedich-166	231	20	university	university	PROPN
biomedich-166	231	21	tayler	tayler	PROPN
biomedich-166	231	22	nm	nm	PROPN
biomedich-166	231	23	,	,	PUNCT
biomedich-166	231	24	de	de	PROPN
biomedich-166	231	25	jesús	jesús	PROPN
biomedich-166	231	26	r	r	NOUN
biomedich-166	231	27	,	,	PUNCT
biomedich-166	231	28	spadafora	spadafora	NOUN
biomedich-166	231	29	r	r	NOUN
biomedich-166	231	30	,	,	PUNCT
biomedich-166	231	31	coronado	coronado	NOUN
biomedich-166	231	32	lm	lm	PROPN
biomedich-166	231	33	,	,	PUNCT
biomedich-166	231	34	r	r	NOUN
biomedich-166	231	35	,	,	PUNCT
biomedich-166	231	36	&	&	CCONJ
biomedich-166	231	37	spadafora	spadafora	PROPN
biomedich-166	231	38	c	c	PROPN
biomedich-166	231	39	(	(	PUNCT
biomedich-166	231	40	2020	2020	NUM
biomedich-166	231	41	)	)	PUNCT
biomedich-166	231	42	antiplasmodial	antiplasmodial	ADJ
biomedich-166	231	43	activity	activity	NOUN
biomedich-166	231	44	of	of	ADP
biomedich-166	231	45	cocos	cocos	PROPN
biomedich-166	231	46	nucifera	nucifera	PROPN
biomedich-166	231	47	leaves	leave	VERB
biomedich-166	231	48	in	in	ADP
biomedich-166	231	49	plasmodium	plasmodium	NOUN
biomedich-166	231	50	berghei	berghei	NOUN
biomedich-166	231	51	-	-	PUNCT
biomedich-166	231	52	infected	infect	VERB
biomedich-166	231	53	mice	mouse	NOUN
biomedich-166	231	54	.	.	PUNCT
biomedich-166	232	1	journal	journal	NOUN
biomedich-166	232	2	of	of	ADP
biomedich-166	232	3	parasitic	parasitic	ADJ
biomedich-166	232	4	disease	disease	NOUN
biomedich-166	232	5	44	44	NUM
biomedich-166	232	6	,	,	PUNCT
biomedich-166	232	7	305–313	305–313	NUM
biomedich-166	232	8	.	.	PUNCT
biomedich-166	233	1	visser	visser	NOUN
biomedich-166	233	2	bj	bj	PROPN
biomedich-166	233	3	,	,	PUNCT
biomedich-166	233	4	wieten	wieten	ADJ
biomedich-166	233	5	rw	rw	NOUN
biomedich-166	233	6	,	,	PUNCT
biomedich-166	233	7	nagel	nagel	PROPN
biomedich-166	233	8	i	i	PROPN
biomedich-166	233	9	m.	m.	PROPN
biomedich-166	233	10	&	&	CCONJ
biomedich-166	233	11	grobusch	grobusch	PROPN
biomedich-166	233	12	mp	mp	PROPN
biomedich-166	233	13	(	(	PUNCT
biomedich-166	233	14	2013	2013	NUM
biomedich-166	233	15	)	)	PUNCT
biomedich-166	233	16	serum	serum	NOUN
biomedich-166	233	17	lipids	lipid	NOUN
biomedich-166	233	18	and	and	CCONJ
biomedich-166	233	19	lipoproteins	lipoprotein	NOUN
biomedich-166	233	20	in	in	ADP
biomedich-166	233	21	malaria	malaria	NOUN
biomedich-166	233	22	a	a	DET
biomedich-166	233	23	systematic	systematic	ADJ
biomedich-166	233	24	review	review	NOUN
biomedich-166	233	25	and	and	CCONJ
biomedich-166	233	26	meta	meta	ADJ
biomedich-166	233	27	-	-	PUNCT
biomedich-166	233	28	analysis	analysis	NOUN
biomedich-166	233	29	.	.	PUNCT
biomedich-166	234	1	malarail	malarail	PROPN
biomedich-166	234	2	journal	journal	PROPN
biomedich-166	234	3	.	.	PUNCT
biomedich-166	235	1	12	12	NUM
biomedich-166	235	2	,	,	PUNCT
biomedich-166	235	3	442	442	NUM
biomedich-166	235	4	,	,	PUNCT
biomedich-166	235	5	1	1	NUM
biomedich-166	235	6	-	-	SYM
biomedich-166	235	7	16	16	NUM
biomedich-166	235	8	who	who	PRON
biomedich-166	235	9	.	.	PUNCT
biomedich-166	236	1	world	world	NOUN
biomedich-166	236	2	malaria	malaria	PROPN
biomedich-166	236	3	report	report	PROPN
biomedich-166	236	4	2016	2016	NUM
biomedich-166	236	5	.	.	PUNCT
biomedich-166	237	1	geneva	geneva	PROPN
biomedich-166	237	2	:	:	PUNCT
biomedich-166	237	3	world	world	PROPN
biomedich-166	237	4	health	health	NOUN
biomedich-166	237	5	organization	organization	NOUN
biomedich-166	237	6	;	;	PUNCT
biomedich-166	237	7	2016	2016	NUM
biomedich-166	237	8	yavo	yavo	NOUN
biomedich-166	237	9	w	w	PROPN
biomedich-166	237	10	,	,	PUNCT
biomedich-166	237	11	faye	faye	PROPN
biomedich-166	237	12	b	b	PROPN
biomedich-166	237	13	,	,	PUNCT
biomedich-166	237	14	kuete	kuete	PROPN
biomedich-166	237	15	t	t	PROPN
biomedich-166	237	16	,	,	PUNCT
biomedich-166	237	17	djohan	djohan	VERB
biomedich-166	237	18	v	v	NOUN
biomedich-166	237	19	,	,	PUNCT
biomedich-166	237	20	oga	oga	PROPN
biomedich-166	237	21	sa	sa	PROPN
biomedich-166	237	22	,	,	PUNCT
biomedich-166	237	23	kassi	kassi	PROPN
biomedich-166	237	24	rr	rr	PROPN
biomedich-166	237	25	et	et	PROPN
biomedich-166	237	26	al	al	PROPN
biomedich-166	237	27	.	.	PROPN
biomedich-166	238	1	(	(	PUNCT
biomedich-166	238	2	2011	2011	NUM
biomedich-166	238	3	)	)	PUNCT
biomedich-166	238	4	.	.	PUNCT
biomedich-166	239	1	multicentric	multicentric	ADJ
biomedich-166	239	2	assessment	assessment	NOUN
biomedich-166	239	3	of	of	ADP
biomedich-166	239	4	the	the	DET
biomedich-166	239	5	efficacy	efficacy	NOUN
biomedich-166	239	6	and	and	CCONJ
biomedich-166	239	7	tolerability	tolerability	NOUN
biomedich-166	239	8	of	of	ADP
biomedich-166	239	9	dihydroartemisinin	dihydroartemisinin	NOUN
biomedich-166	239	10	-	-	PUNCT
biomedich-166	239	11	piperaquine	piperaquine	NOUN
biomedich-166	239	12	compared	compare	VERB
biomedich-166	239	13	to	to	ADP
biomedich-166	239	14	artemether	artemether	ADJ
biomedich-166	239	15	-	-	PUNCT
biomedich-166	239	16	lumefantrine	lumefantrine	NOUN
biomedich-166	239	17	in	in	ADP
biomedich-166	239	18	the	the	DET
biomedich-166	239	19	treatment	treatment	NOUN
biomedich-166	239	20	of	of	ADP
biomedich-166	239	21	uncomplicated	uncomplicated	ADJ
biomedich-166	239	22	plasmodium	plasmodium	NOUN
biomedich-166	239	23	falciparum	falciparum	ADJ
biomedich-166	239	24	malaria	malaria	NOUN
biomedich-166	239	25	in	in	ADP
biomedich-166	239	26	sub	sub	ADJ
biomedich-166	239	27	-	-	ADJ
biomedich-166	239	28	saharan	saharan	ADJ
biomedich-166	239	29	africa	africa	PROPN
biomedich-166	239	30	.	.	PUNCT
biomedich-166	240	1	malarial	malarial	ADJ
biomedich-166	240	2	journal	journal	PROPN
biomedich-166	240	3	.	.	PUNCT
biomedich-166	241	1	2011	2011	NUM
biomedich-166	241	2	;	;	PUNCT
biomedich-166	241	3	10:198	10:198	NUM
biomedich-166	241	4	.	.	PUNCT
biomedich-166	242	1	yeo	yeo	PROPN
biomedich-166	242	2	ae	ae	PROPN
biomedich-166	242	3	,	,	PUNCT
biomedich-166	242	4	edstein	edstein	PROPN
biomedich-166	242	5	md	md	PROPN
biomedich-166	242	6	,	,	PUNCT
biomedich-166	242	7	shanks	shank	NOUN
biomedich-166	242	8	gd	gd	PROPN
biomedich-166	242	9	,	,	PUNCT
biomedich-166	242	10	&	&	CCONJ
biomedich-166	242	11	rieckmann	rieckmann	PROPN
biomedich-166	242	12	kh	kh	PROPN
biomedich-166	242	13	(	(	PUNCT
biomedich-166	242	14	1997	1997	NUM
biomedich-166	242	15	)	)	PUNCT
biomedich-166	242	16	.	.	PUNCT
biomedich-166	243	1	potentiation	potentiation	NOUN
biomedich-166	243	2	of	of	ADP
biomedich-166	243	3	the	the	DET
biomedich-166	243	4	antimalarial	antimalarial	ADJ
biomedich-166	243	5	activity	activity	NOUN
biomedich-166	243	6	of	of	ADP
biomedich-166	243	7	atovaquone	atovaquone	NOUN
biomedich-166	243	8	by	by	ADP
biomedich-166	243	9	doxycycline	doxycycline	NOUN
biomedich-166	243	10	against	against	ADP
biomedich-166	243	11	plasmodium	plasmodium	NOUN
biomedich-166	243	12	falciparum	falciparum	NOUN
biomedich-166	243	13	in	in	ADP
biomedich-166	243	14	vitro	vitro	X
biomedich-166	243	15	.	.	PUNCT
biomedich-166	244	1	parasitology	parasitology	NOUN
biomedich-166	244	2	research	research	NOUN
biomedich-166	244	3	.	.	PUNCT
biomedich-166	245	1	83:489–91	83:489–91	PROPN
biomedich-166	245	2	.	.	PUNCT
biomedich-166	246	1	https://www.ncbi.nlm.nih.gov/pubmed/?term=tan%20kr%5bauthor%5d&cauthor=true&cauthor_uid=21460003	https://www.ncbi.nlm.nih.gov/pubmed/?term=tan%20kr%5bauthor%5d&cauthor=true&cauthor_uid=21460003	PROPN
biomedich-166	246	2	https://www.ncbi.nlm.nih.gov/pubmed/?term=magill%20aj%5bauthor%5d&cauthor=true&cauthor_uid=21460003	https://www.ncbi.nlm.nih.gov/pubmed/?term=magill%20aj%5bauthor%5d&cauthor=true&cauthor_uid=21460003	SYM
biomedich-166	246	3	https://www.ncbi.nlm.nih.gov/pubmed/?term=parise%20me%5bauthor%5d&cauthor=true&cauthor_uid=21460003	https://www.ncbi.nlm.nih.gov/pubmed/?term=parise%20me%5bauthor%5d&cauthor=true&cauthor_uid=21460003	NOUN
biomedich-166	246	4	https://www.ncbi.nlm.nih.gov/pubmed/?term=arguin%20pm%5bauthor%5d&cauthor=true&cauthor_uid=21460003	https://www.ncbi.nlm.nih.gov/pubmed/?term=arguin%20pm%5bauthor%5d&cauthor=true&cauthor_uid=21460003	X