id	sid	tid	token	lemma	pos
biomedich-167	1	1	biology	biology	NOUN
biomedich-167	1	2	,	,	PUNCT
biomedich-167	1	3	medicine	medicine	NOUN
biomedich-167	1	4	,	,	PUNCT
biomedich-167	1	5	&	&	CCONJ
biomedich-167	1	6	natural	natural	ADJ
biomedich-167	1	7	product	product	NOUN
biomedich-167	1	8	chemistry	chemistry	NOUN
biomedich-167	1	9	issn	issn	VERB
biomedich-167	1	10	2089	2089	NUM
biomedich-167	1	11	-	-	SYM
biomedich-167	1	12	6514	6514	NUM
biomedich-167	1	13	(	(	PUNCT
biomedich-167	1	14	paper	paper	NOUN
biomedich-167	1	15	)	)	PUNCT
biomedich-167	1	16	volume	volume	NOUN
biomedich-167	1	17	11	11	NUM
biomedich-167	1	18	,	,	PUNCT
biomedich-167	1	19	number	number	NOUN
biomedich-167	1	20	1	1	NUM
biomedich-167	1	21	,	,	PUNCT
biomedich-167	1	22	april	april	PROPN
biomedich-167	1	23	2022	2022	NUM
biomedich-167	2	1	|	|	ADV
biomedich-167	2	2	pages	page	NOUN
biomedich-167	2	3	:	:	PUNCT
biomedich-167	2	4	1	1	NUM
biomedich-167	2	5	-	-	SYM
biomedich-167	2	6	6	6	NUM
biomedich-167	2	7	|	|	ADV
biomedich-167	2	8	doi	doi	NOUN
biomedich-167	2	9	:	:	PUNCT
biomedich-167	2	10	10.14421	10.14421	NUM
biomedich-167	2	11	/	/	SYM
biomedich-167	2	12	biomedich.2022.111.1	biomedich.2022.111.1	NOUN
biomedich-167	2	13	-	-	SYM
biomedich-167	2	14	6	6	NUM
biomedich-167	2	15	issn	issn	PROPN
biomedich-167	2	16	2540	2540	NUM
biomedich-167	2	17	-	-	SYM
biomedich-167	2	18	9328	9328	NUM
biomedich-167	2	19	(	(	PUNCT
biomedich-167	2	20	online	online	ADJ
biomedich-167	2	21	)	)	PUNCT
biomedich-167	2	22	potential	potential	ADJ
biomedich-167	2	23	antimalarial	antimalarial	ADJ
biomedich-167	2	24	activity	activity	NOUN
biomedich-167	2	25	of	of	ADP
biomedich-167	2	26	artemether	artemether	ADJ
biomedich-167	2	27	/	/	SYM
biomedich-167	2	28	lumefantrine	lumefantrine	ADJ
biomedich-167	2	29	/	/	SYM
biomedich-167	2	30	doxycycline	doxycycline	NOUN
biomedich-167	2	31	:	:	PUNCT
biomedich-167	2	32	a	a	DET
biomedich-167	2	33	study	study	NOUN
biomedich-167	2	34	in	in	ADP
biomedich-167	2	35	mice	mouse	NOUN
biomedich-167	2	36	infected	infect	VERB
biomedich-167	2	37	with	with	ADP
biomedich-167	2	38	plasmodium	plasmodium	NOUN
biomedich-167	2	39	berghei	berghei	NOUN
biomedich-167	2	40	udeme	udeme	PROPN
biomedich-167	2	41	owunari	owunari	PROPN
biomedich-167	2	42	georgewill1	georgewill1	PROPN
biomedich-167	2	43	,	,	PUNCT
biomedich-167	2	44	*	*	PROPN
biomedich-167	2	45	,	,	PUNCT
biomedich-167	2	46	elias	elias	PROPN
biomedich-167	2	47	adikwu2	adikwu2	PROPN
biomedich-167	3	1	1department	1department	NUM
biomedich-167	3	2	of	of	ADP
biomedich-167	3	3	pharmacology	pharmacology	NOUN
biomedich-167	3	4	,	,	PUNCT
biomedich-167	3	5	faculty	faculty	NOUN
biomedich-167	3	6	of	of	ADP
biomedich-167	3	7	basic	basic	ADJ
biomedich-167	3	8	clinical	clinical	ADJ
biomedich-167	3	9	sciences	science	NOUN
biomedich-167	3	10	,	,	PUNCT
biomedich-167	3	11	university	university	NOUN
biomedich-167	3	12	of	of	ADP
biomedich-167	3	13	port	port	NOUN
biomedich-167	3	14	harcourt	harcourt	PROPN
biomedich-167	3	15	,	,	PUNCT
biomedich-167	3	16	rivers	river	NOUN
biomedich-167	3	17	state	state	PROPN
biomedich-167	3	18	,	,	PUNCT
biomedich-167	3	19	nigeria	nigeria	PROPN
biomedich-167	4	1	2department	2department	NUM
biomedich-167	4	2	of	of	ADP
biomedich-167	4	3	pharmacology	pharmacology	NOUN
biomedich-167	4	4	and	and	CCONJ
biomedich-167	4	5	toxicology	toxicology	NOUN
biomedich-167	4	6	,	,	PUNCT
biomedich-167	4	7	faculty	faculty	NOUN
biomedich-167	4	8	of	of	ADP
biomedich-167	4	9	pharmacy	pharmacy	NOUN
biomedich-167	4	10	,	,	PUNCT
biomedich-167	4	11	niger	niger	PROPN
biomedich-167	4	12	delta	delta	PROPN
biomedich-167	4	13	university	university	NOUN
biomedich-167	4	14	,	,	PUNCT
biomedich-167	4	15	bayelsa	bayelsa	NOUN
biomedich-167	4	16	state	state	NOUN
biomedich-167	4	17	,	,	PUNCT
biomedich-167	4	18	nigeria	nigeria	PROPN
biomedich-167	4	19	.	.	PUNCT
biomedich-167	5	1	corresponding	correspond	VERB
biomedich-167	5	2	author	author	NOUN
biomedich-167	5	3	*	*	PROPN
biomedich-167	5	4	udgeorgewill@yahoo.com	udgeorgewill@yahoo.com	PROPN
biomedich-167	5	5	,	,	PUNCT
biomedich-167	5	6	tel+234	tel+234	PROPN
biomedich-167	5	7	8036662936	8036662936	NUM
biomedich-167	5	8	manuscript	manuscript	NOUN
biomedich-167	5	9	received	receive	VERB
biomedich-167	5	10	:	:	PUNCT
biomedich-167	5	11	08	08	NUM
biomedich-167	5	12	december	december	PROPN
biomedich-167	5	13	2021	2021	NUM
biomedich-167	5	14	.	.	PUNCT
biomedich-167	6	1	revision	revision	NOUN
biomedich-167	6	2	accepted	accept	VERB
biomedich-167	6	3	:	:	PUNCT
biomedich-167	6	4	11	11	NUM
biomedich-167	6	5	january	january	PROPN
biomedich-167	6	6	,	,	PUNCT
biomedich-167	6	7	2022	2022	NUM
biomedich-167	6	8	.	.	PUNCT
biomedich-167	7	1	published	publish	VERB
biomedich-167	7	2	:	:	PUNCT
biomedich-167	7	3	09	09	NUM
biomedich-167	7	4	february	february	NOUN
biomedich-167	7	5	,	,	PUNCT
biomedich-167	7	6	2022	2022	NUM
biomedich-167	7	7	.	.	PUNCT
biomedich-167	8	1	abstract	abstract	ADJ
biomedich-167	8	2	antimalarial	antimalarial	ADJ
biomedich-167	8	3	drug	drug	NOUN
biomedich-167	8	4	resistance	resistance	NOUN
biomedich-167	8	5	is	be	AUX
biomedich-167	8	6	one	one	NUM
biomedich-167	8	7	of	of	ADP
biomedich-167	8	8	the	the	DET
biomedich-167	8	9	greatest	great	ADJ
biomedich-167	8	10	challenges	challenge	NOUN
biomedich-167	8	11	towards	towards	ADP
biomedich-167	8	12	eradicating	eradicate	VERB
biomedich-167	8	13	malaria	malaria	NOUN
biomedich-167	8	14	.	.	PUNCT
biomedich-167	9	1	exploring	explore	VERB
biomedich-167	9	2	new	new	ADJ
biomedich-167	9	3	combination	combination	NOUN
biomedich-167	9	4	therapies	therapy	NOUN
biomedich-167	9	5	can	can	AUX
biomedich-167	9	6	overcome	overcome	VERB
biomedich-167	9	7	resistance	resistance	NOUN
biomedich-167	9	8	challenges	challenge	NOUN
biomedich-167	9	9	.	.	PUNCT
biomedich-167	10	1	the	the	DET
biomedich-167	10	2	present	present	ADJ
biomedich-167	10	3	study	study	NOUN
biomedich-167	10	4	examined	examine	VERB
biomedich-167	10	5	the	the	DET
biomedich-167	10	6	antiplasmodial	antiplasmodial	ADJ
biomedich-167	10	7	effect	effect	NOUN
biomedich-167	10	8	of	of	ADP
biomedich-167	10	9	artemether	artemether	ADJ
biomedich-167	10	10	/	/	SYM
biomedich-167	10	11	lumefantrine	lumefantrine	ADJ
biomedich-167	10	12	/	/	SYM
biomedich-167	10	13	doxycycline	doxycycline	NOUN
biomedich-167	10	14	(	(	PUNCT
biomedich-167	10	15	a	a	NOUN
biomedich-167	10	16	/	/	SYM
biomedich-167	10	17	l	l	NOUN
biomedich-167	10	18	/	/	SYM
biomedich-167	10	19	d	d	NOUN
biomedich-167	10	20	)	)	PUNCT
biomedich-167	10	21	on	on	ADP
biomedich-167	10	22	a	a	DET
biomedich-167	10	23	mouse	mouse	NOUN
biomedich-167	10	24	model	model	NOUN
biomedich-167	10	25	infected	infect	VERB
biomedich-167	10	26	with	with	ADP
biomedich-167	10	27	plasmodium	plasmodium	NOUN
biomedich-167	10	28	berghei	berghei	PROPN
biomedich-167	10	29	.	.	PUNCT
biomedich-167	11	1	adult	adult	NOUN
biomedich-167	11	2	swiss	swiss	ADJ
biomedich-167	11	3	albino	albino	NOUN
biomedich-167	11	4	mice	mouse	NOUN
biomedich-167	11	5	(	(	PUNCT
biomedich-167	11	6	22	22	NUM
biomedich-167	11	7	-	-	SYM
biomedich-167	11	8	30	30	NUM
biomedich-167	11	9	g	g	NOUN
biomedich-167	11	10	)	)	PUNCT
biomedich-167	11	11	intraperitoneally	intraperitoneally	ADV
biomedich-167	11	12	infected	infect	VERB
biomedich-167	11	13	with	with	ADP
biomedich-167	11	14	blood	blood	NOUN
biomedich-167	11	15	containing	contain	VERB
biomedich-167	11	16	1x107	1x107	NUM
biomedich-167	11	17	plasmodium	plasmodium	NOUN
biomedich-167	11	18	berghei	berghei	NOUN
biomedich-167	11	19	were	be	AUX
biomedich-167	11	20	randomly	randomly	ADV
biomedich-167	11	21	grouped	group	VERB
biomedich-167	11	22	and	and	CCONJ
biomedich-167	11	23	orally	orally	ADV
biomedich-167	11	24	treated	treat	VERB
biomedich-167	11	25	daily	daily	ADV
biomedich-167	11	26	with	with	ADP
biomedich-167	11	27	d	d	PROPN
biomedich-167	11	28	(	(	PUNCT
biomedich-167	11	29	2.2	2.2	NUM
biomedich-167	11	30	mg	mg	PROPN
biomedich-167	11	31	/	/	SYM
biomedich-167	11	32	kg	kg	PROPN
biomedich-167	11	33	)	)	PUNCT
biomedich-167	11	34	,	,	PUNCT
biomedich-167	11	35	a	a	X
biomedich-167	11	36	/	/	SYM
biomedich-167	11	37	l	l	NOUN
biomedich-167	11	38	(	(	PUNCT
biomedich-167	11	39	1.71/13.7	1.71/13.7	NUM
biomedich-167	11	40	mg	mg	PROPN
biomedich-167	11	41	/	/	SYM
biomedich-167	11	42	kg	kg	PROPN
biomedich-167	11	43	)	)	PUNCT
biomedich-167	11	44	and	and	CCONJ
biomedich-167	11	45	a	a	DET
biomedich-167	11	46	/	/	SYM
biomedich-167	11	47	l	l	NOUN
biomedich-167	11	48	/	/	SYM
biomedich-167	11	49	d.	d.	NOUN
biomedich-167	11	50	the	the	DET
biomedich-167	11	51	negative	negative	ADJ
biomedich-167	11	52	control	control	NOUN
biomedich-167	11	53	was	be	AUX
biomedich-167	11	54	treated	treat	VERB
biomedich-167	11	55	daily	daily	ADV
biomedich-167	11	56	with	with	ADP
biomedich-167	11	57	normal	normal	ADJ
biomedich-167	11	58	saline	saline	NOUN
biomedich-167	11	59	(	(	PUNCT
biomedich-167	11	60	0.2ml	0.2ml	NUM
biomedich-167	11	61	)	)	PUNCT
biomedich-167	11	62	whereas	whereas	SCONJ
biomedich-167	11	63	the	the	DET
biomedich-167	11	64	positive	positive	ADJ
biomedich-167	11	65	control	control	NOUN
biomedich-167	11	66	was	be	AUX
biomedich-167	11	67	treated	treat	VERB
biomedich-167	11	68	daily	daily	ADV
biomedich-167	11	69	with	with	ADP
biomedich-167	11	70	chloroquine	chloroquine	NOUN
biomedich-167	11	71	(	(	PUNCT
biomedich-167	11	72	cq	cq	NOUN
biomedich-167	11	73	)	)	PUNCT
biomedich-167	11	74	(	(	PUNCT
biomedich-167	11	75	10mg	10mg	NOUN
biomedich-167	11	76	/	/	SYM
biomedich-167	11	77	kg	kg	NOUN
biomedich-167	11	78	)	)	PUNCT
biomedich-167	11	79	.	.	PUNCT
biomedich-167	12	1	after	after	ADP
biomedich-167	12	2	treatment	treatment	NOUN
biomedich-167	12	3	,	,	PUNCT
biomedich-167	12	4	blood	blood	NOUN
biomedich-167	12	5	samples	sample	NOUN
biomedich-167	12	6	were	be	AUX
biomedich-167	12	7	assessed	assess	VERB
biomedich-167	12	8	for	for	ADP
biomedich-167	12	9	percentage	percentage	NOUN
biomedich-167	12	10	parasitemia	parasitemia	NOUN
biomedich-167	12	11	and	and	CCONJ
biomedich-167	12	12	biochemical	biochemical	ADJ
biomedich-167	12	13	parameters	parameter	NOUN
biomedich-167	12	14	.	.	PUNCT
biomedich-167	13	1	mice	mouse	NOUN
biomedich-167	13	2	were	be	AUX
biomedich-167	13	3	observed	observe	VERB
biomedich-167	13	4	for	for	ADP
biomedich-167	13	5	mean	mean	ADJ
biomedich-167	13	6	survival	survival	NOUN
biomedich-167	13	7	time	time	NOUN
biomedich-167	13	8	(	(	PUNCT
biomedich-167	13	9	mst	mst	PROPN
biomedich-167	13	10	)	)	PUNCT
biomedich-167	13	11	.	.	PUNCT
biomedich-167	14	1	d	d	X
biomedich-167	14	2	,	,	PUNCT
biomedich-167	14	3	a	a	DET
biomedich-167	14	4	/	/	SYM
biomedich-167	14	5	l	l	NOUN
biomedich-167	14	6	and	and	CCONJ
biomedich-167	14	7	a	a	DET
biomedich-167	14	8	/	/	SYM
biomedich-167	14	9	l	l	NOUN
biomedich-167	14	10	/	/	SYM
biomedich-167	14	11	d	d	NOUN
biomedich-167	14	12	produced	produce	VERB
biomedich-167	14	13	significant	significant	ADJ
biomedich-167	14	14	decreases	decrease	NOUN
biomedich-167	14	15	in	in	ADP
biomedich-167	14	16	percentage	percentage	NOUN
biomedich-167	14	17	parasitemia	parasitemia	NOUN
biomedich-167	14	18	levels	level	NOUN
biomedich-167	14	19	at	at	ADP
biomedich-167	14	20	p<0.05	p<0.05	NOUN
biomedich-167	14	21	;	;	PUNCT
biomedich-167	14	22	p<0.01	p<0.01	PROPN
biomedich-167	14	23	and	and	CCONJ
biomedich-167	14	24	p<0.001	p<0.001	PROPN
biomedich-167	14	25	,	,	PUNCT
biomedich-167	14	26	respectively	respectively	ADV
biomedich-167	14	27	when	when	SCONJ
biomedich-167	14	28	compared	compare	VERB
biomedich-167	14	29	to	to	ADP
biomedich-167	14	30	negative	negative	ADJ
biomedich-167	14	31	control	control	NOUN
biomedich-167	14	32	.	.	PUNCT
biomedich-167	15	1	in	in	ADP
biomedich-167	15	2	the	the	DET
biomedich-167	15	3	curative	curative	ADJ
biomedich-167	15	4	test	test	NOUN
biomedich-167	15	5	,	,	PUNCT
biomedich-167	15	6	d	d	X
biomedich-167	15	7	,	,	PUNCT
biomedich-167	15	8	a	a	DET
biomedich-167	15	9	/	/	SYM
biomedich-167	15	10	l	l	NOUN
biomedich-167	15	11	and	and	CCONJ
biomedich-167	15	12	a	a	DET
biomedich-167	15	13	/	/	SYM
biomedich-167	15	14	l	l	NOUN
biomedich-167	15	15	/	/	SYM
biomedich-167	15	16	d	d	NOUN
biomedich-167	15	17	produced	produce	VERB
biomedich-167	15	18	60.4	60.4	NUM
biomedich-167	15	19	%	%	NOUN
biomedich-167	15	20	,	,	PUNCT
biomedich-167	15	21	70.3	70.3	NUM
biomedich-167	15	22	%	%	NOUN
biomedich-167	15	23	,	,	PUNCT
biomedich-167	15	24	and	and	CCONJ
biomedich-167	15	25	90.0	90.0	NUM
biomedich-167	15	26	%	%	NOUN
biomedich-167	15	27	parasitemia	parasitemia	NOUN
biomedich-167	15	28	inhibitions	inhibition	NOUN
biomedich-167	15	29	,	,	PUNCT
biomedich-167	15	30	respectively	respectively	ADV
biomedich-167	15	31	whereas	whereas	SCONJ
biomedich-167	15	32	cq	cq	NOUN
biomedich-167	15	33	produced	produce	VERB
biomedich-167	15	34	76.0	76.0	NUM
biomedich-167	15	35	%	%	NOUN
biomedich-167	15	36	parasitemia	parasitemia	NOUN
biomedich-167	15	37	inhibition	inhibition	NOUN
biomedich-167	15	38	.	.	PUNCT
biomedich-167	16	1	d	d	X
biomedich-167	16	2	,	,	PUNCT
biomedich-167	16	3	a	a	DET
biomedich-167	16	4	/	/	SYM
biomedich-167	16	5	l	l	NOUN
biomedich-167	16	6	,	,	PUNCT
biomedich-167	16	7	a	a	DET
biomedich-167	16	8	/	/	SYM
biomedich-167	16	9	l	l	NOUN
biomedich-167	16	10	/	/	SYM
biomedich-167	16	11	d	d	PROPN
biomedich-167	16	12	and	and	CCONJ
biomedich-167	16	13	cq	cq	PROPN
biomedich-167	16	14	produced	produce	VERB
biomedich-167	16	15	63.2	63.2	NUM
biomedich-167	16	16	%	%	NOUN
biomedich-167	16	17	,	,	PUNCT
biomedich-167	16	18	80.1	80.1	NUM
biomedich-167	16	19	%	%	NOUN
biomedich-167	16	20	,	,	PUNCT
biomedich-167	16	21	92.3	92.3	NUM
biomedich-167	16	22	%	%	NOUN
biomedich-167	16	23	and	and	CCONJ
biomedich-167	16	24	83.6	83.6	NUM
biomedich-167	16	25	%	%	NOUN
biomedich-167	16	26	parasitemia	parasitemia	NOUN
biomedich-167	16	27	inhibitions	inhibition	NOUN
biomedich-167	16	28	,	,	PUNCT
biomedich-167	16	29	respectively	respectively	ADV
biomedich-167	16	30	in	in	ADP
biomedich-167	16	31	the	the	DET
biomedich-167	16	32	suppressive	suppressive	ADJ
biomedich-167	16	33	test	test	NOUN
biomedich-167	16	34	.	.	PUNCT
biomedich-167	17	1	d	d	X
biomedich-167	17	2	,	,	PUNCT
biomedich-167	17	3	a	a	DET
biomedich-167	17	4	/	/	SYM
biomedich-167	17	5	l	l	NOUN
biomedich-167	17	6	,	,	PUNCT
biomedich-167	17	7	and	and	CCONJ
biomedich-167	17	8	a	a	DET
biomedich-167	17	9	/	/	SYM
biomedich-167	17	10	l	l	NOUN
biomedich-167	17	11	/	/	SYM
biomedich-167	17	12	d	d	NOUN
biomedich-167	17	13	prevented	prevent	VERB
biomedich-167	17	14	plasmodium	plasmodium	NOUN
biomedich-167	17	15	bergheiinduced	bergheiinduce	VERB
biomedich-167	17	16	alterations	alteration	NOUN
biomedich-167	17	17	in	in	ADP
biomedich-167	17	18	biochemical	biochemical	ADJ
biomedich-167	17	19	parameters	parameter	NOUN
biomedich-167	17	20	by	by	ADP
biomedich-167	17	21	increasing	increase	VERB
biomedich-167	17	22	packed	pack	VERB
biomedich-167	17	23	cell	cell	NOUN
biomedich-167	17	24	volume	volume	NOUN
biomedich-167	17	25	,	,	PUNCT
biomedich-167	17	26	red	red	ADJ
biomedich-167	17	27	blood	blood	NOUN
biomedich-167	17	28	cells	cell	NOUN
biomedich-167	17	29	,	,	PUNCT
biomedich-167	17	30	hemoglobin	hemoglobin	NOUN
biomedich-167	17	31	,	,	PUNCT
biomedich-167	17	32	and	and	CCONJ
biomedich-167	17	33	high	high	ADJ
biomedich-167	17	34	-	-	PUNCT
biomedich-167	17	35	density	density	NOUN
biomedich-167	17	36	lipoprotein	lipoprotein	ADJ
biomedich-167	17	37	and	and	CCONJ
biomedich-167	17	38	decreasing	decrease	VERB
biomedich-167	17	39	white	white	ADJ
biomedich-167	17	40	blood	blood	NOUN
biomedich-167	17	41	cells	cell	NOUN
biomedich-167	17	42	,	,	PUNCT
biomedich-167	17	43	total	total	ADJ
biomedich-167	17	44	cholesterol	cholesterol	NOUN
biomedich-167	17	45	,	,	PUNCT
biomedich-167	17	46	low	low	ADJ
biomedich-167	17	47	-	-	PUNCT
biomedich-167	17	48	density	density	NOUN
biomedich-167	17	49	lipoprotein	lipoprotein	ADJ
biomedich-167	17	50	cholesterol	cholesterol	NOUN
biomedich-167	17	51	,	,	PUNCT
biomedich-167	17	52	and	and	CCONJ
biomedich-167	17	53	triglyceride	triglyceride	ADJ
biomedich-167	17	54	levels	level	NOUN
biomedich-167	17	55	significantly	significantly	ADV
biomedich-167	17	56	at	at	ADP
biomedich-167	17	57	p<0.05	p<0.05	NOUN
biomedich-167	17	58	and	and	CCONJ
biomedich-167	17	59	p<0.01	p<0.01	PROPN
biomedich-167	17	60	and	and	CCONJ
biomedich-167	17	61	p<0.001	p<0.001	PROPN
biomedich-167	17	62	,	,	PUNCT
biomedich-167	17	63	respectively	respectively	ADV
biomedich-167	17	64	when	when	SCONJ
biomedich-167	17	65	compared	compare	VERB
biomedich-167	17	66	to	to	ADP
biomedich-167	17	67	the	the	DET
biomedich-167	17	68	negative	negative	ADJ
biomedich-167	17	69	control	control	NOUN
biomedich-167	17	70	.	.	PUNCT
biomedich-167	18	1	a	a	PRON
biomedich-167	18	2	/	/	SYM
biomedich-167	18	3	l	l	NOUN
biomedich-167	18	4	/	/	SYM
biomedich-167	18	5	d	d	NOUN
biomedich-167	18	6	produced	produce	VERB
biomedich-167	18	7	significant	significant	ADJ
biomedich-167	18	8	antiplasmodial	antiplasmodial	ADJ
biomedich-167	18	9	activity	activity	NOUN
biomedich-167	18	10	therefore	therefore	ADV
biomedich-167	18	11	,	,	PUNCT
biomedich-167	18	12	it	it	PRON
biomedich-167	18	13	may	may	AUX
biomedich-167	18	14	be	be	AUX
biomedich-167	18	15	used	use	VERB
biomedich-167	18	16	clinically	clinically	ADV
biomedich-167	18	17	for	for	ADP
biomedich-167	18	18	the	the	DET
biomedich-167	18	19	treatment	treatment	NOUN
biomedich-167	18	20	of	of	ADP
biomedich-167	18	21	malaria	malaria	NOUN
biomedich-167	18	22	.	.	PUNCT
biomedich-167	19	1	keywords	keyword	NOUN
biomedich-167	19	2	;	;	PUNCT
biomedich-167	19	3	antiplasmodial	antiplasmodial	ADJ
biomedich-167	19	4	;	;	PUNCT
biomedich-167	19	5	artemether	artemether	ADJ
biomedich-167	19	6	;	;	PUNCT
biomedich-167	19	7	tetracycline	tetracycline	NOUN
biomedich-167	19	8	;	;	PUNCT
biomedich-167	19	9	antimalarial	antimalarial	NOUN
biomedich-167	19	10	;	;	PUNCT
biomedich-167	19	11	lumefantrine	lumefantrine	ADJ
biomedich-167	19	12	;	;	PUNCT
biomedich-167	19	13	plasmodium	plasmodium	NOUN
biomedich-167	19	14	berghei	berghei	NOUN
biomedich-167	19	15	.	.	PUNCT
biomedich-167	20	1	introduction	introduction	NOUN
biomedich-167	20	2	antimalarial	antimalarial	ADJ
biomedich-167	20	3	drug	drug	NOUN
biomedich-167	20	4	resistance	resistance	NOUN
biomedich-167	20	5	has	have	AUX
biomedich-167	20	6	been	be	AUX
biomedich-167	20	7	acknowledged	acknowledge	VERB
biomedich-167	20	8	to	to	PART
biomedich-167	20	9	be	be	AUX
biomedich-167	20	10	one	one	NUM
biomedich-167	20	11	of	of	ADP
biomedich-167	20	12	the	the	DET
biomedich-167	20	13	greatest	great	ADJ
biomedich-167	20	14	challenges	challenge	NOUN
biomedich-167	20	15	to	to	ADP
biomedich-167	20	16	the	the	DET
biomedich-167	20	17	roll	roll	NOUN
biomedich-167	20	18	back	back	ADP
biomedich-167	20	19	malaria	malaria	NOUN
biomedich-167	20	20	programme	programme	NOUN
biomedich-167	20	21	.	.	PUNCT
biomedich-167	21	1	the	the	DET
biomedich-167	21	2	situation	situation	NOUN
biomedich-167	21	3	is	be	AUX
biomedich-167	21	4	highly	highly	ADV
biomedich-167	21	5	precarious	precarious	ADJ
biomedich-167	21	6	due	due	ADP
biomedich-167	21	7	to	to	ADP
biomedich-167	21	8	the	the	DET
biomedich-167	21	9	rising	rise	VERB
biomedich-167	21	10	incidence	incidence	NOUN
biomedich-167	21	11	of	of	ADP
biomedich-167	21	12	plasmodium	plasmodium	NOUN
biomedich-167	21	13	resistance	resistance	NOUN
biomedich-167	21	14	to	to	ADP
biomedich-167	21	15	currently	currently	ADV
biomedich-167	21	16	available	available	ADJ
biomedich-167	21	17	antimalarial	antimalarial	ADJ
biomedich-167	21	18	drugs	drug	NOUN
biomedich-167	21	19	(	(	PUNCT
biomedich-167	21	20	yeung	yeung	PROPN
biomedich-167	21	21	et	et	PROPN
biomedich-167	21	22	al	al	PROPN
biomedich-167	21	23	.	.	PROPN
biomedich-167	21	24	,	,	PUNCT
biomedich-167	21	25	2004	2004	NUM
biomedich-167	21	26	)	)	PUNCT
biomedich-167	21	27	.	.	PUNCT
biomedich-167	22	1	chloroquine	chloroquine	NOUN
biomedich-167	22	2	(	(	PUNCT
biomedich-167	22	3	cq	cq	NOUN
biomedich-167	22	4	)	)	PUNCT
biomedich-167	22	5	resistant	resistant	ADJ
biomedich-167	22	6	plasmodium	plasmodium	NOUN
biomedich-167	22	7	falciparum	falciparum	NOUN
biomedich-167	22	8	now	now	ADV
biomedich-167	22	9	predominates	predominate	VERB
biomedich-167	22	10	in	in	ADP
biomedich-167	22	11	southeast	southeast	PROPN
biomedich-167	22	12	asia	asia	PROPN
biomedich-167	22	13	,	,	PUNCT
biomedich-167	22	14	south	south	PROPN
biomedich-167	22	15	america	america	PROPN
biomedich-167	22	16	and	and	CCONJ
biomedich-167	22	17	africa	africa	PROPN
biomedich-167	22	18	.	.	PUNCT
biomedich-167	23	1	resistance	resistance	NOUN
biomedich-167	23	2	to	to	ADP
biomedich-167	23	3	sulphadoxinepyrimethamine	sulphadoxinepyrimethamine	NOUN
biomedich-167	23	4	is	be	AUX
biomedich-167	23	5	widespread	widespread	ADJ
biomedich-167	23	6	in	in	ADP
biomedich-167	23	7	asia	asia	PROPN
biomedich-167	23	8	and	and	CCONJ
biomedich-167	23	9	south	south	PROPN
biomedich-167	23	10	america	america	PROPN
biomedich-167	23	11	and	and	CCONJ
biomedich-167	23	12	is	be	AUX
biomedich-167	23	13	spreading	spread	VERB
biomedich-167	23	14	in	in	ADP
biomedich-167	23	15	africa	africa	PROPN
biomedich-167	23	16	and	and	CCONJ
biomedich-167	23	17	even	even	ADV
biomedich-167	23	18	quinine	quinine	PROPN
biomedich-167	23	19	has	have	AUX
biomedich-167	23	20	become	become	VERB
biomedich-167	23	21	less	less	ADV
biomedich-167	23	22	effective	effective	ADJ
biomedich-167	23	23	over	over	ADP
biomedich-167	23	24	time	time	NOUN
biomedich-167	23	25	(	(	PUNCT
biomedich-167	23	26	khan	khan	PROPN
biomedich-167	23	27	et	et	PROPN
biomedich-167	23	28	al	al	PROPN
biomedich-167	23	29	.	.	PROPN
biomedich-167	23	30	,	,	PUNCT
biomedich-167	23	31	2004	2004	NUM
biomedich-167	23	32	)	)	PUNCT
biomedich-167	23	33	.	.	PUNCT
biomedich-167	24	1	the	the	DET
biomedich-167	24	2	use	use	NOUN
biomedich-167	24	3	of	of	ADP
biomedich-167	24	4	combination	combination	NOUN
biomedich-167	24	5	therapy	therapy	NOUN
biomedich-167	24	6	with	with	ADP
biomedich-167	24	7	artemisinins	artemisinin	NOUN
biomedich-167	24	8	and	and	CCONJ
biomedich-167	24	9	partner	partner	NOUN
biomedich-167	24	10	drugs	drug	NOUN
biomedich-167	24	11	has	have	AUX
biomedich-167	24	12	been	be	AUX
biomedich-167	24	13	a	a	DET
biomedich-167	24	14	rational	rational	ADJ
biomedich-167	24	15	approach	approach	NOUN
biomedich-167	24	16	to	to	ADP
biomedich-167	24	17	combating	combat	VERB
biomedich-167	24	18	drug	drug	NOUN
biomedich-167	24	19	resistance	resistance	NOUN
biomedich-167	24	20	.	.	PUNCT
biomedich-167	25	1	drugs	drug	NOUN
biomedich-167	25	2	with	with	ADP
biomedich-167	25	3	different	different	ADJ
biomedich-167	25	4	mechanisms	mechanism	NOUN
biomedich-167	25	5	of	of	ADP
biomedich-167	25	6	action	action	NOUN
biomedich-167	25	7	may	may	AUX
biomedich-167	25	8	enhance	enhance	VERB
biomedich-167	25	9	their	their	PRON
biomedich-167	25	10	respective	respective	ADJ
biomedich-167	25	11	efficacies	efficacy	NOUN
biomedich-167	25	12	and	and	CCONJ
biomedich-167	25	13	extend	extend	VERB
biomedich-167	25	14	their	their	PRON
biomedich-167	25	15	therapeutic	therapeutic	ADJ
biomedich-167	25	16	life	life	NOUN
biomedich-167	25	17	spans	span	NOUN
biomedich-167	25	18	(	(	PUNCT
biomedich-167	25	19	white	white	PROPN
biomedich-167	25	20	&	&	CCONJ
biomedich-167	25	21	olliaro	olliaro	NOUN
biomedich-167	25	22	,	,	PUNCT
biomedich-167	25	23	1996	1996	NUM
biomedich-167	25	24	)	)	PUNCT
biomedich-167	25	25	.	.	PUNCT
biomedich-167	26	1	despite	despite	SCONJ
biomedich-167	26	2	,	,	PUNCT
biomedich-167	26	3	the	the	DET
biomedich-167	26	4	combination	combination	NOUN
biomedich-167	26	5	therapy	therapy	NOUN
biomedich-167	26	6	approach	approach	NOUN
biomedich-167	26	7	,	,	PUNCT
biomedich-167	26	8	plasmodium	plasmodium	NOUN
biomedich-167	26	9	resistance	resistance	NOUN
biomedich-167	26	10	is	be	AUX
biomedich-167	26	11	still	still	ADV
biomedich-167	26	12	a	a	DET
biomedich-167	26	13	serious	serious	ADJ
biomedich-167	26	14	challenge	challenge	NOUN
biomedich-167	26	15	(	(	PUNCT
biomedich-167	26	16	yeung	yeung	PROPN
biomedich-167	26	17	et	et	PROPN
biomedich-167	26	18	al	al	PROPN
biomedich-167	26	19	.	.	PROPN
biomedich-167	26	20	,	,	PUNCT
biomedich-167	26	21	2004	2004	NUM
biomedich-167	26	22	)	)	PUNCT
biomedich-167	26	23	.	.	PUNCT
biomedich-167	27	1	doxycycline	doxycycline	NOUN
biomedich-167	27	2	(	(	PUNCT
biomedich-167	27	3	d	d	X
biomedich-167	27	4	)	)	PUNCT
biomedich-167	27	5	is	be	AUX
biomedich-167	27	6	one	one	NUM
biomedich-167	27	7	of	of	ADP
biomedich-167	27	8	the	the	DET
biomedich-167	27	9	most	most	ADV
biomedich-167	27	10	active	active	ADJ
biomedich-167	27	11	antibiotics	antibiotic	NOUN
biomedich-167	27	12	against	against	ADP
biomedich-167	27	13	plasmodium	plasmodium	NOUN
biomedich-167	27	14	parasites	parasite	NOUN
biomedich-167	27	15	.	.	PUNCT
biomedich-167	28	1	it	it	PRON
biomedich-167	28	2	belongs	belong	VERB
biomedich-167	28	3	to	to	ADP
biomedich-167	28	4	the	the	DET
biomedich-167	28	5	tetracycline	tetracycline	PROPN
biomedich-167	28	6	family	family	NOUN
biomedich-167	28	7	.	.	PUNCT
biomedich-167	29	1	the	the	DET
biomedich-167	29	2	tetracyclines	tetracycline	NOUN
biomedich-167	29	3	,	,	PUNCT
biomedich-167	29	4	which	which	PRON
biomedich-167	29	5	have	have	VERB
biomedich-167	29	6	a	a	DET
biomedich-167	29	7	very	very	ADV
biomedich-167	29	8	wide	wide	ADJ
biomedich-167	29	9	spectrum	spectrum	NOUN
biomedich-167	29	10	of	of	ADP
biomedich-167	29	11	activity	activity	NOUN
biomedich-167	29	12	are	be	AUX
biomedich-167	29	13	bacteriostatic	bacteriostatic	ADJ
biomedich-167	29	14	and	and	CCONJ
biomedich-167	29	15	inhibit	inhibit	VERB
biomedich-167	29	16	bacterial	bacterial	ADJ
biomedich-167	29	17	protein	protein	NOUN
biomedich-167	29	18	synthesis	synthesis	NOUN
biomedich-167	29	19	(	(	PUNCT
biomedich-167	29	20	gaillard	gaillard	PROPN
biomedich-167	29	21	et	et	PROPN
biomedich-167	29	22	al	al	PROPN
biomedich-167	29	23	.	.	PROPN
biomedich-167	29	24	,	,	PUNCT
biomedich-167	29	25	2015	2015	NUM
biomedich-167	29	26	)	)	PUNCT
biomedich-167	29	27	.	.	PUNCT
biomedich-167	30	1	among	among	ADP
biomedich-167	30	2	the	the	DET
biomedich-167	30	3	tetracyclines	tetracycline	NOUN
biomedich-167	30	4	,	,	PUNCT
biomedich-167	30	5	d	d	PROPN
biomedich-167	30	6	is	be	AUX
biomedich-167	30	7	widely	widely	ADV
biomedich-167	30	8	used	use	VERB
biomedich-167	30	9	for	for	ADP
biomedich-167	30	10	malaria	malaria	NOUN
biomedich-167	30	11	prophylaxis	prophylaxis	NOUN
biomedich-167	30	12	and	and	CCONJ
biomedich-167	30	13	is	be	AUX
biomedich-167	30	14	highly	highly	ADV
biomedich-167	30	15	acceptable	acceptable	ADJ
biomedich-167	30	16	for	for	ADP
biomedich-167	30	17	long	long	ADJ
biomedich-167	30	18	-	-	PUNCT
biomedich-167	30	19	term	term	NOUN
biomedich-167	30	20	therapy	therapy	NOUN
biomedich-167	30	21	,	,	PUNCT
biomedich-167	30	22	except	except	SCONJ
biomedich-167	30	23	in	in	ADP
biomedich-167	30	24	pregnant	pregnant	ADJ
biomedich-167	30	25	women	woman	NOUN
biomedich-167	30	26	and	and	CCONJ
biomedich-167	30	27	children	child	NOUN
biomedich-167	30	28	(	(	PUNCT
biomedich-167	30	29	who	who	PRON
biomedich-167	30	30	,	,	PUNCT
biomedich-167	30	31	2005	2005	NUM
biomedich-167	30	32	)	)	PUNCT
biomedich-167	30	33	.	.	PUNCT
biomedich-167	31	1	in	in	ADP
biomedich-167	31	2	-	-	PUNCT
biomedich-167	31	3	vitro	vitro	X
biomedich-167	31	4	and	and	CCONJ
biomedich-167	31	5	in	in	ADP
biomedich-167	31	6	-	-	PUNCT
biomedich-167	31	7	vivo	vivo	NOUN
biomedich-167	31	8	investigations	investigation	NOUN
biomedich-167	31	9	have	have	AUX
biomedich-167	31	10	shown	show	VERB
biomedich-167	31	11	that	that	SCONJ
biomedich-167	31	12	d	d	NOUN
biomedich-167	31	13	may	may	AUX
biomedich-167	31	14	be	be	AUX
biomedich-167	31	15	an	an	DET
biomedich-167	31	16	effective	effective	ADJ
biomedich-167	31	17	antimalarial	antimalarial	ADJ
biomedich-167	31	18	drug	drug	NOUN
biomedich-167	31	19	against	against	ADP
biomedich-167	31	20	drug	drug	NOUN
biomedich-167	31	21	-	-	PUNCT
biomedich-167	31	22	resistant	resistant	ADJ
biomedich-167	31	23	plasmodium	plasmodium	NOUN
biomedich-167	31	24	strains	strain	NOUN
biomedich-167	31	25	(	(	PUNCT
biomedich-167	31	26	basco	basco	PROPN
biomedich-167	31	27	&	&	CCONJ
biomedich-167	31	28	bras	bras	PROPN
biomedich-167	31	29	,	,	PUNCT
biomedich-167	31	30	1993	1993	NUM
biomedich-167	31	31	)	)	PUNCT
biomedich-167	31	32	.	.	PUNCT
biomedich-167	32	1	it	it	PRON
biomedich-167	32	2	is	be	AUX
biomedich-167	32	3	used	use	VERB
biomedich-167	32	4	in	in	ADP
biomedich-167	32	5	combination	combination	NOUN
biomedich-167	32	6	with	with	ADP
biomedich-167	32	7	quinine	quinine	NOUN
biomedich-167	32	8	as	as	ADP
biomedich-167	32	9	an	an	DET
biomedich-167	32	10	effective	effective	ADJ
biomedich-167	32	11	standby	standby	ADJ
biomedich-167	32	12	emergency	emergency	NOUN
biomedich-167	32	13	treatment	treatment	NOUN
biomedich-167	32	14	of	of	ADP
biomedich-167	32	15	malaria	malaria	NOUN
biomedich-167	32	16	associated	associate	VERB
biomedich-167	32	17	with	with	ADP
biomedich-167	32	18	plasmodium	plasmodium	NOUN
biomedich-167	32	19	falciparum	falciparum	NOUN
biomedich-167	32	20	(	(	PUNCT
biomedich-167	32	21	who	who	PRON
biomedich-167	32	22	,	,	PUNCT
biomedich-167	32	23	2005	2005	NUM
biomedich-167	32	24	)	)	PUNCT
biomedich-167	32	25	.	.	PUNCT
biomedich-167	33	1	recently	recently	ADV
biomedich-167	33	2	,	,	PUNCT
biomedich-167	33	3	it	it	PRON
biomedich-167	33	4	has	have	AUX
biomedich-167	33	5	shown	show	VERB
biomedich-167	33	6	antimalarial	antimalarial	ADJ
biomedich-167	33	7	potential	potential	NOUN
biomedich-167	33	8	against	against	ADP
biomedich-167	33	9	plasmodium	plasmodium	NOUN
biomedich-167	33	10	bergheiinduced	bergheiinduce	VERB
biomedich-167	33	11	cerebral	cerebral	ADJ
biomedich-167	33	12	malaria	malaria	NOUN
biomedich-167	33	13	in	in	ADP
biomedich-167	33	14	experimental	experimental	ADJ
biomedich-167	33	15	models	model	NOUN
biomedich-167	33	16	by	by	ADP
biomedich-167	33	17	inhibiting	inhibit	VERB
biomedich-167	33	18	brain	brain	NOUN
biomedich-167	33	19	inflammation	inflammation	NOUN
biomedich-167	33	20	,	,	PUNCT
biomedich-167	33	21	tumour	tumour	NOUN
biomedich-167	33	22	necrosis	necrosis	NOUN
biomedich-167	33	23	factor	factor	NOUN
biomedich-167	33	24	and	and	CCONJ
biomedich-167	33	25	chemokines	chemokine	NOUN
biomedich-167	33	26	expressions	expression	NOUN
biomedich-167	33	27	(	(	PUNCT
biomedich-167	33	28	schmidt	schmidt	PROPN
biomedich-167	33	29	et	et	PROPN
biomedich-167	33	30	al	al	PROPN
biomedich-167	33	31	.	.	PROPN
biomedich-167	33	32	,	,	PUNCT
biomedich-167	33	33	2018	2018	NUM
biomedich-167	33	34	)	)	PUNCT
biomedich-167	33	35	.	.	PUNCT
biomedich-167	34	1	artemether	artemether	ADJ
biomedich-167	34	2	/	/	SYM
biomedich-167	34	3	lumefantrine	lumefantrine	NOUN
biomedich-167	34	4	(	(	PUNCT
biomedich-167	34	5	a	a	DET
biomedich-167	34	6	/	/	SYM
biomedich-167	34	7	l	l	NOUN
biomedich-167	34	8	)	)	PUNCT
biomedich-167	34	9	is	be	AUX
biomedich-167	34	10	an	an	DET
biomedich-167	34	11	artemisininbased	artemisininbase	VERB
biomedich-167	34	12	antimalarial	antimalarial	ADJ
biomedich-167	34	13	drug	drug	NOUN
biomedich-167	34	14	approved	approve	VERB
biomedich-167	34	15	by	by	ADP
biomedich-167	34	16	the	the	DET
biomedich-167	34	17	us	us	PROPN
biomedich-167	34	18	food	food	NOUN
biomedich-167	34	19	and	and	CCONJ
biomedich-167	34	20	https://doi.org/10.14421/biomedich.2022.111.1-6	https://doi.org/10.14421/biomedich.2022.111.1-6	PROPN
biomedich-167	34	21	2	2	NUM
biomedich-167	34	22	biology	biology	NOUN
biomedich-167	34	23	,	,	PUNCT
biomedich-167	34	24	medicine	medicine	NOUN
biomedich-167	34	25	,	,	PUNCT
biomedich-167	34	26	&	&	CCONJ
biomedich-167	34	27	natural	natural	ADJ
biomedich-167	34	28	product	product	NOUN
biomedich-167	34	29	chemistry	chemistry	NOUN
biomedich-167	34	30	11	11	NUM
biomedich-167	34	31	(	(	PUNCT
biomedich-167	34	32	1	1	NUM
biomedich-167	34	33	)	)	PUNCT
biomedich-167	34	34	,	,	PUNCT
biomedich-167	34	35	2022	2022	NUM
biomedich-167	34	36	:	:	PUNCT
biomedich-167	34	37	1	1	NUM
biomedich-167	34	38	-	-	SYM
biomedich-167	34	39	6	6	NUM
biomedich-167	34	40	drug	drug	NOUN
biomedich-167	34	41	administration	administration	NOUN
biomedich-167	34	42	in	in	ADP
biomedich-167	34	43	2009	2009	NUM
biomedich-167	34	44	for	for	ADP
biomedich-167	34	45	the	the	DET
biomedich-167	34	46	treatment	treatment	NOUN
biomedich-167	34	47	of	of	ADP
biomedich-167	34	48	plasmodium	plasmodium	NOUN
biomedich-167	34	49	falciparum	falciparum	ADJ
biomedich-167	34	50	malaria	malaria	NOUN
biomedich-167	34	51	.	.	PUNCT
biomedich-167	35	1	the	the	DET
biomedich-167	35	2	dual	dual	ADJ
biomedich-167	35	3	mechanisms	mechanism	NOUN
biomedich-167	35	4	of	of	ADP
biomedich-167	35	5	action	action	NOUN
biomedich-167	35	6	of	of	ADP
biomedich-167	35	7	a	a	DET
biomedich-167	35	8	/	/	SYM
biomedich-167	35	9	l	l	NOUN
biomedich-167	35	10	provide	provide	VERB
biomedich-167	35	11	fast	fast	ADJ
biomedich-167	35	12	and	and	CCONJ
biomedich-167	35	13	sustained	sustained	ADJ
biomedich-167	35	14	plasmodium	plasmodium	NOUN
biomedich-167	35	15	clearance	clearance	NOUN
biomedich-167	35	16	(	(	PUNCT
biomedich-167	35	17	stover	stover	NOUN
biomedich-167	35	18	et	et	PROPN
biomedich-167	35	19	al	al	PROPN
biomedich-167	35	20	.	.	PROPN
biomedich-167	35	21	,	,	PUNCT
biomedich-167	35	22	2012	2012	NUM
biomedich-167	35	23	)	)	PUNCT
biomedich-167	35	24	.	.	PUNCT
biomedich-167	36	1	it	it	PRON
biomedich-167	36	2	is	be	AUX
biomedich-167	36	3	the	the	DET
biomedich-167	36	4	most	most	ADV
biomedich-167	36	5	widely	widely	ADV
biomedich-167	36	6	used	use	VERB
biomedich-167	36	7	antimalarial	antimalarial	ADJ
biomedich-167	36	8	drug	drug	NOUN
biomedich-167	36	9	combination	combination	NOUN
biomedich-167	36	10	in	in	ADP
biomedich-167	36	11	endemic	endemic	ADJ
biomedich-167	36	12	regions	region	NOUN
biomedich-167	36	13	.	.	PUNCT
biomedich-167	37	1	in	in	ADP
biomedich-167	37	2	2017	2017	NUM
biomedich-167	37	3	,	,	PUNCT
biomedich-167	37	4	a	a	DET
biomedich-167	37	5	/	/	SYM
biomedich-167	37	6	l	l	NOUN
biomedich-167	37	7	accounted	account	VERB
biomedich-167	37	8	for	for	ADP
biomedich-167	37	9	almost	almost	ADV
biomedich-167	37	10	75	75	NUM
biomedich-167	37	11	%	%	NOUN
biomedich-167	37	12	of	of	ADP
biomedich-167	37	13	all	all	PRON
biomedich-167	37	14	purchased	purchase	VERB
biomedich-167	37	15	and	and	CCONJ
biomedich-167	37	16	clinically	clinically	ADV
biomedich-167	37	17	used	use	VERB
biomedich-167	37	18	artemisinin	artemisinin	NOUN
biomedich-167	37	19	based	base	VERB
biomedich-167	37	20	combination	combination	NOUN
biomedich-167	37	21	therapies	therapy	NOUN
biomedich-167	37	22	(	(	PUNCT
biomedich-167	37	23	acts	act	NOUN
biomedich-167	37	24	)	)	PUNCT
biomedich-167	37	25	(	(	PUNCT
biomedich-167	37	26	nsanzabana	nsanzabana	ADJ
biomedich-167	37	27	,	,	PUNCT
biomedich-167	37	28	2019	2019	NUM
biomedich-167	37	29	)	)	PUNCT
biomedich-167	37	30	.	.	PUNCT
biomedich-167	38	1	artemisinin	artemisinin	PROPN
biomedich-167	38	2	derivatives	derivative	NOUN
biomedich-167	38	3	rapidly	rapidly	ADV
biomedich-167	38	4	clear	clear	ADJ
biomedich-167	38	5	parasites	parasite	NOUN
biomedich-167	38	6	through	through	ADP
biomedich-167	38	7	a	a	DET
biomedich-167	38	8	number	number	NOUN
biomedich-167	38	9	of	of	ADP
biomedich-167	38	10	proposed	propose	VERB
biomedich-167	38	11	mechanisms	mechanism	NOUN
biomedich-167	38	12	such	such	ADJ
biomedich-167	38	13	as	as	ADP
biomedich-167	38	14	interference	interference	NOUN
biomedich-167	38	15	with	with	ADP
biomedich-167	38	16	plasmodial	plasmodial	ADJ
biomedich-167	38	17	transport	transport	NOUN
biomedich-167	38	18	proteins	protein	NOUN
biomedich-167	38	19	,	,	PUNCT
biomedich-167	38	20	interference	interference	NOUN
biomedich-167	38	21	with	with	ADP
biomedich-167	38	22	plasmodial	plasmodial	ADJ
biomedich-167	38	23	mitochondrial	mitochondrial	ADJ
biomedich-167	38	24	electron	electron	NOUN
biomedich-167	38	25	transport	transport	NOUN
biomedich-167	38	26	,	,	PUNCT
biomedich-167	38	27	and	and	CCONJ
biomedich-167	38	28	the	the	DET
biomedich-167	38	29	production	production	NOUN
biomedich-167	38	30	of	of	ADP
biomedich-167	38	31	free	free	ADJ
biomedich-167	38	32	radicals	radical	NOUN
biomedich-167	38	33	(	(	PUNCT
biomedich-167	38	34	stover	stover	NOUN
biomedich-167	38	35	et	et	PROPN
biomedich-167	38	36	al	al	PROPN
biomedich-167	38	37	.	.	PROPN
biomedich-167	38	38	,	,	PUNCT
biomedich-167	38	39	2012	2012	NUM
biomedich-167	38	40	)	)	PUNCT
biomedich-167	38	41	.	.	PUNCT
biomedich-167	39	1	the	the	DET
biomedich-167	39	2	precise	precise	ADJ
biomedich-167	39	3	mechanism	mechanism	NOUN
biomedich-167	39	4	for	for	ADP
biomedich-167	39	5	the	the	DET
biomedich-167	39	6	antiplasmodial	antiplasmodial	ADJ
biomedich-167	39	7	activity	activity	NOUN
biomedich-167	39	8	of	of	ADP
biomedich-167	39	9	lumefantrine	lumefantrine	NOUN
biomedich-167	39	10	is	be	AUX
biomedich-167	39	11	not	not	PART
biomedich-167	39	12	well	well	ADV
biomedich-167	39	13	defined	define	VERB
biomedich-167	39	14	,	,	PUNCT
biomedich-167	39	15	but	but	CCONJ
biomedich-167	39	16	it	it	PRON
biomedich-167	39	17	is	be	AUX
biomedich-167	39	18	proposed	propose	VERB
biomedich-167	39	19	to	to	PART
biomedich-167	39	20	inhibit	inhibit	VERB
biomedich-167	39	21	β	β	NOUN
biomedich-167	39	22	-	-	PUNCT
biomedich-167	39	23	hematin	hematin	ADJ
biomedich-167	39	24	formation	formation	NOUN
biomedich-167	39	25	,	,	PUNCT
biomedich-167	39	26	which	which	PRON
biomedich-167	39	27	is	be	AUX
biomedich-167	39	28	an	an	DET
biomedich-167	39	29	important	important	ADJ
biomedich-167	39	30	detoxification	detoxification	NOUN
biomedich-167	39	31	pathway	pathway	NOUN
biomedich-167	39	32	for	for	ADP
biomedich-167	39	33	plasmodium	plasmodium	NOUN
biomedich-167	39	34	parasites	parasite	NOUN
biomedich-167	39	35	(	(	PUNCT
biomedich-167	39	36	stover	stover	NOUN
biomedich-167	39	37	et	et	PROPN
biomedich-167	39	38	al	al	PROPN
biomedich-167	39	39	.	.	PROPN
biomedich-167	39	40	,	,	PUNCT
biomedich-167	39	41	2012	2012	NUM
biomedich-167	39	42	)	)	PUNCT
biomedich-167	39	43	.	.	PUNCT
biomedich-167	40	1	despite	despite	SCONJ
biomedich-167	40	2	the	the	DET
biomedich-167	40	3	success	success	NOUN
biomedich-167	40	4	achieved	achieve	VERB
biomedich-167	40	5	with	with	ADP
biomedich-167	40	6	the	the	DET
biomedich-167	40	7	use	use	NOUN
biomedich-167	40	8	of	of	ADP
biomedich-167	40	9	a	a	DET
biomedich-167	40	10	/	/	SYM
biomedich-167	40	11	l	l	NOUN
biomedich-167	40	12	in	in	ADP
biomedich-167	40	13	combating	combat	VERB
biomedich-167	40	14	malaria	malaria	NOUN
biomedich-167	40	15	scourge	scourge	NOUN
biomedich-167	40	16	,	,	PUNCT
biomedich-167	40	17	the	the	DET
biomedich-167	40	18	emergence	emergence	NOUN
biomedich-167	40	19	of	of	ADP
biomedich-167	40	20	plasmodium	plasmodium	NOUN
biomedich-167	40	21	parasite	parasite	NOUN
biomedich-167	40	22	resistance	resistance	NOUN
biomedich-167	40	23	in	in	ADP
biomedich-167	40	24	some	some	DET
biomedich-167	40	25	endemic	endemic	ADJ
biomedich-167	40	26	countries	country	NOUN
biomedich-167	40	27	has	have	AUX
biomedich-167	40	28	become	become	VERB
biomedich-167	40	29	a	a	DET
biomedich-167	40	30	significant	significant	ADJ
biomedich-167	40	31	drawback	drawback	NOUN
biomedich-167	40	32	for	for	ADP
biomedich-167	40	33	the	the	DET
biomedich-167	40	34	fight	fight	NOUN
biomedich-167	40	35	against	against	ADP
biomedich-167	40	36	malaria	malaria	NOUN
biomedich-167	40	37	(	(	PUNCT
biomedich-167	40	38	nsanzabana	nsanzabana	ADJ
biomedich-167	40	39	,	,	PUNCT
biomedich-167	40	40	2019	2019	NUM
biomedich-167	40	41	)	)	PUNCT
biomedich-167	40	42	.	.	PUNCT
biomedich-167	41	1	due	due	ADP
biomedich-167	41	2	to	to	ADP
biomedich-167	41	3	the	the	DET
biomedich-167	41	4	challenge	challenge	NOUN
biomedich-167	41	5	posed	pose	VERB
biomedich-167	41	6	by	by	ADP
biomedich-167	41	7	plasmodium	plasmodium	NOUN
biomedich-167	41	8	parasite	parasite	NOUN
biomedich-167	41	9	resistance	resistance	NOUN
biomedich-167	41	10	,	,	PUNCT
biomedich-167	41	11	there	there	PRON
biomedich-167	41	12	is	be	VERB
biomedich-167	41	13	a	a	DET
biomedich-167	41	14	strong	strong	ADJ
biomedich-167	41	15	advocacy	advocacy	NOUN
biomedich-167	41	16	for	for	ADP
biomedich-167	41	17	the	the	DET
biomedich-167	41	18	rational	rational	ADJ
biomedich-167	41	19	use	use	NOUN
biomedich-167	41	20	of	of	ADP
biomedich-167	41	21	antimalarial	antimalarial	ADJ
biomedich-167	41	22	drugs	drug	NOUN
biomedich-167	41	23	with	with	ADP
biomedich-167	41	24	antibiotics	antibiotic	NOUN
biomedich-167	41	25	.	.	PUNCT
biomedich-167	42	1	this	this	PRON
biomedich-167	42	2	will	will	AUX
biomedich-167	42	3	afford	afford	VERB
biomedich-167	42	4	the	the	DET
biomedich-167	42	5	synergistic	synergistic	ADJ
biomedich-167	42	6	or	or	CCONJ
biomedich-167	42	7	additive	additive	ADJ
biomedich-167	42	8	killing	killing	NOUN
biomedich-167	42	9	of	of	ADP
biomedich-167	42	10	plasmodium	plasmodium	NOUN
biomedich-167	42	11	parasites	parasite	NOUN
biomedich-167	42	12	,	,	PUNCT
biomedich-167	42	13	and	and	CCONJ
biomedich-167	42	14	thus	thus	ADV
biomedich-167	42	15	prevent	prevent	VERB
biomedich-167	42	16	or	or	CCONJ
biomedich-167	42	17	reduce	reduce	VERB
biomedich-167	42	18	drug	drug	NOUN
biomedich-167	42	19	resistance	resistance	NOUN
biomedich-167	42	20	(	(	PUNCT
biomedich-167	42	21	miller	miller	PROPN
biomedich-167	42	22	et	et	PROPN
biomedich-167	42	23	al	al	PROPN
biomedich-167	42	24	.	.	PROPN
biomedich-167	42	25	,	,	PUNCT
biomedich-167	42	26	2006	2006	NUM
biomedich-167	42	27	;	;	PUNCT
biomedich-167	42	28	alecrim	alecrim	PROPN
biomedich-167	42	29	et	et	PROPN
biomedich-167	42	30	al	al	PROPN
biomedich-167	42	31	.	.	PROPN
biomedich-167	42	32	,	,	PUNCT
biomedich-167	42	33	2006	2006	NUM
biomedich-167	42	34	)	)	PUNCT
biomedich-167	42	35	.	.	PUNCT
biomedich-167	43	1	this	this	DET
biomedich-167	43	2	study	study	NOUN
biomedich-167	43	3	,	,	PUNCT
biomedich-167	43	4	therefore	therefore	ADV
biomedich-167	43	5	assessed	assess	VERB
biomedich-167	43	6	the	the	DET
biomedich-167	43	7	antiplasmodial	antiplasmodial	ADJ
biomedich-167	43	8	effect	effect	NOUN
biomedich-167	43	9	of	of	ADP
biomedich-167	43	10	a	a	DET
biomedich-167	43	11	/	/	SYM
biomedich-167	43	12	l	l	NOUN
biomedich-167	43	13	/	/	SYM
biomedich-167	43	14	d	d	NOUN
biomedich-167	43	15	on	on	ADP
biomedich-167	43	16	a	a	DET
biomedich-167	43	17	mouse	mouse	NOUN
biomedich-167	43	18	model	model	NOUN
biomedich-167	43	19	infected	infect	VERB
biomedich-167	43	20	with	with	ADP
biomedich-167	43	21	plasmodium	plasmodium	NOUN
biomedich-167	43	22	berghei	berghei	NOUN
biomedich-167	43	23	.	.	PUNCT
biomedich-167	44	1	materials	material	NOUN
biomedich-167	44	2	and	and	CCONJ
biomedich-167	44	3	methods	method	NOUN
biomedich-167	44	4	drugs	drug	NOUN
biomedich-167	44	5	and	and	CCONJ
biomedich-167	44	6	dose	dose	NOUN
biomedich-167	44	7	selection	selection	NOUN
biomedich-167	44	8	artemether	artemether	ADJ
biomedich-167	44	9	/	/	SYM
biomedich-167	44	10	lumefantrine	lumefantrine	NOUN
biomedich-167	44	11	(	(	PUNCT
biomedich-167	44	12	a	a	DET
biomedich-167	44	13	/	/	SYM
biomedich-167	44	14	l	l	NOUN
biomedich-167	44	15	)	)	PUNCT
biomedich-167	44	16	(	(	PUNCT
biomedich-167	44	17	ipac	ipac	PROPN
biomedich-167	44	18	laboratory	laboratory	PROPN
biomedich-167	44	19	,	,	PUNCT
biomedich-167	44	20	india	india	PROPN
biomedich-167	44	21	)	)	PUNCT
biomedich-167	44	22	,	,	PUNCT
biomedich-167	44	23	chloroquine	chloroquine	NOUN
biomedich-167	44	24	(	(	PUNCT
biomedich-167	44	25	cq	cq	NOUN
biomedich-167	44	26	)	)	PUNCT
biomedich-167	44	27	(	(	PUNCT
biomedich-167	44	28	evans	evans	PROPN
biomedich-167	44	29	medical	medical	PROPN
biomedich-167	44	30	nigeria	nigeria	PROPN
biomedich-167	44	31	plc	plc	PROPN
biomedich-167	44	32	)	)	PUNCT
biomedich-167	44	33	,	,	PUNCT
biomedich-167	44	34	and	and	CCONJ
biomedich-167	44	35	doxycycline	doxycycline	NOUN
biomedich-167	44	36	(	(	PUNCT
biomedich-167	44	37	d	d	X
biomedich-167	44	38	)	)	PUNCT
biomedich-167	44	39	(	(	PUNCT
biomedich-167	44	40	ranbaxy	ranbaxy	PROPN
biomedich-167	44	41	laboratories	laboratories	PROPN
biomedich-167	44	42	ltd	ltd	PROPN
biomedich-167	44	43	,	,	PUNCT
biomedich-167	44	44	india	india	PROPN
biomedich-167	44	45	)	)	PUNCT
biomedich-167	44	46	were	be	AUX
biomedich-167	44	47	used	use	VERB
biomedich-167	44	48	.	.	PUNCT
biomedich-167	45	1	the	the	DET
biomedich-167	45	2	following	follow	VERB
biomedich-167	45	3	doses	dose	NOUN
biomedich-167	45	4	were	be	AUX
biomedich-167	45	5	used	use	VERB
biomedich-167	45	6	:	:	PUNCT
biomedich-167	45	7	a	a	X
biomedich-167	45	8	/	/	SYM
biomedich-167	45	9	l	l	NOUN
biomedich-167	45	10	(	(	PUNCT
biomedich-167	45	11	2.3/13.7	2.3/13.7	NUM
biomedich-167	45	12	mg	mg	PROPN
biomedich-167	45	13	/	/	SYM
biomedich-167	45	14	kg	kg	NOUN
biomedich-167	45	15	)	)	PUNCT
biomedich-167	45	16	(	(	PUNCT
biomedich-167	45	17	sirima	sirima	NOUN
biomedich-167	45	18	et	et	PROPN
biomedich-167	45	19	al	al	PROPN
biomedich-167	45	20	.	.	PROPN
biomedich-167	45	21	,	,	PUNCT
biomedich-167	45	22	2016	2016	NUM
biomedich-167	45	23	)	)	PUNCT
biomedich-167	45	24	,	,	PUNCT
biomedich-167	45	25	cq	cq	PROPN
biomedich-167	46	1	(	(	PUNCT
biomedich-167	46	2	10mg	10mg	PROPN
biomedich-167	46	3	/	/	SYM
biomedich-167	46	4	kg	kg	NOUN
biomedich-167	46	5	)	)	PUNCT
biomedich-167	46	6	(	(	PUNCT
biomedich-167	46	7	somsak	somsak	NOUN
biomedich-167	46	8	et	et	PROPN
biomedich-167	46	9	al	al	PROPN
biomedich-167	46	10	.	.	PROPN
biomedich-167	46	11	,	,	PUNCT
biomedich-167	46	12	2018	2018	NUM
biomedich-167	46	13	)	)	PUNCT
biomedich-167	46	14	,	,	PUNCT
biomedich-167	46	15	and	and	CCONJ
biomedich-167	46	16	d	d	X
biomedich-167	46	17	(	(	PUNCT
biomedich-167	46	18	2.2	2.2	NUM
biomedich-167	46	19	mg	mg	PROPN
biomedich-167	46	20	/	/	SYM
biomedich-167	46	21	kg	kg	NOUN
biomedich-167	46	22	)	)	PUNCT
biomedich-167	46	23	(	(	PUNCT
biomedich-167	46	24	gaillard	gaillard	PROPN
biomedich-167	46	25	et	et	PROPN
biomedich-167	46	26	al	al	PROPN
biomedich-167	46	27	.	.	PROPN
biomedich-167	46	28	,	,	PUNCT
biomedich-167	46	29	2015	2015	NUM
biomedich-167	46	30	)	)	PUNCT
biomedich-167	46	31	animals	animal	NOUN
biomedich-167	46	32	adult	adult	VERB
biomedich-167	46	33	swiss	swiss	ADJ
biomedich-167	46	34	albino	albino	NOUN
biomedich-167	46	35	mice	mouse	NOUN
biomedich-167	46	36	(	(	PUNCT
biomedich-167	46	37	22–30	22–30	NUM
biomedich-167	46	38	g	g	NOUN
biomedich-167	46	39	)	)	PUNCT
biomedich-167	46	40	were	be	AUX
biomedich-167	46	41	used	use	VERB
biomedich-167	46	42	.	.	PUNCT
biomedich-167	47	1	the	the	DET
biomedich-167	47	2	mice	mouse	NOUN
biomedich-167	47	3	were	be	AUX
biomedich-167	47	4	obtained	obtain	VERB
biomedich-167	47	5	from	from	ADP
biomedich-167	47	6	the	the	DET
biomedich-167	47	7	animal	animal	NOUN
biomedich-167	47	8	unit	unit	NOUN
biomedich-167	47	9	of	of	ADP
biomedich-167	47	10	the	the	DET
biomedich-167	47	11	department	department	PROPN
biomedich-167	47	12	of	of	ADP
biomedich-167	47	13	pharmacology	pharmacology	NOUN
biomedich-167	47	14	,	,	PUNCT
biomedich-167	47	15	faculty	faculty	NOUN
biomedich-167	47	16	of	of	ADP
biomedich-167	47	17	basic	basic	ADJ
biomedich-167	47	18	clinical	clinical	ADJ
biomedich-167	47	19	sciences	science	NOUN
biomedich-167	47	20	,	,	PUNCT
biomedich-167	47	21	college	college	NOUN
biomedich-167	47	22	of	of	ADP
biomedich-167	47	23	health	health	PROPN
biomedich-167	47	24	sciences	sciences	PROPN
biomedich-167	47	25	,	,	PUNCT
biomedich-167	47	26	university	university	NOUN
biomedich-167	47	27	of	of	ADP
biomedich-167	47	28	port	port	NOUN
biomedich-167	47	29	harcourt	harcourt	PROPN
biomedich-167	47	30	,	,	PUNCT
biomedich-167	47	31	rivers	river	NOUN
biomedich-167	47	32	state	state	NOUN
biomedich-167	47	33	.	.	PUNCT
biomedich-167	48	1	the	the	DET
biomedich-167	48	2	mice	mouse	NOUN
biomedich-167	48	3	were	be	AUX
biomedich-167	48	4	housed	house	VERB
biomedich-167	48	5	and	and	CCONJ
biomedich-167	48	6	fed	feed	VERB
biomedich-167	48	7	throughout	throughout	ADP
biomedich-167	48	8	the	the	DET
biomedich-167	48	9	study	study	NOUN
biomedich-167	48	10	period	period	NOUN
biomedich-167	48	11	as	as	ADP
biomedich-167	48	12	per	per	ADP
biomedich-167	48	13	recommended	recommend	VERB
biomedich-167	48	14	standards	standard	NOUN
biomedich-167	48	15	.	.	PUNCT
biomedich-167	49	1	the	the	DET
biomedich-167	49	2	mice	mouse	NOUN
biomedich-167	49	3	were	be	AUX
biomedich-167	49	4	allowed	allow	VERB
biomedich-167	49	5	for	for	ADP
biomedich-167	49	6	2	2	NUM
biomedich-167	49	7	weeks	week	NOUN
biomedich-167	49	8	to	to	PART
biomedich-167	49	9	acclimatize	acclimatize	VERB
biomedich-167	49	10	to	to	ADP
biomedich-167	49	11	working	work	VERB
biomedich-167	49	12	environment	environment	NOUN
biomedich-167	49	13	and	and	CCONJ
biomedich-167	49	14	were	be	AUX
biomedich-167	49	15	handled	handle	VERB
biomedich-167	49	16	according	accord	VERB
biomedich-167	49	17	to	to	ADP
biomedich-167	49	18	the	the	DET
biomedich-167	49	19	international	international	ADJ
biomedich-167	49	20	animal	animal	NOUN
biomedich-167	49	21	care	care	NOUN
biomedich-167	49	22	and	and	CCONJ
biomedich-167	49	23	welfare	welfare	NOUN
biomedich-167	49	24	guidelines	guideline	NOUN
biomedich-167	49	25	(	(	PUNCT
biomedich-167	49	26	ilar	ilar	NOUN
biomedich-167	49	27	,	,	PUNCT
biomedich-167	49	28	2011	2011	NUM
biomedich-167	49	29	)	)	PUNCT
biomedich-167	49	30	.	.	PUNCT
biomedich-167	50	1	parasites	parasite	NOUN
biomedich-167	50	2	inoculation	inoculation	PROPN
biomedich-167	50	3	cq	cq	PROPN
biomedich-167	50	4	-	-	PUNCT
biomedich-167	50	5	sensitive	sensitive	ADJ
biomedich-167	50	6	plasmodium	plasmodium	NOUN
biomedich-167	50	7	berghei	berghei	NOUN
biomedich-167	50	8	(	(	PUNCT
biomedich-167	50	9	p.	p.	PROPN
biomedich-167	50	10	berghei	berghei	PROPN
biomedich-167	50	11	)	)	PUNCT
biomedich-167	50	12	(	(	PUNCT
biomedich-167	50	13	nk65	nk65	PROPN
biomedich-167	50	14	strain	strain	PROPN
biomedich-167	50	15	)	)	PUNCT
biomedich-167	50	16	was	be	AUX
biomedich-167	50	17	used	use	VERB
biomedich-167	50	18	for	for	ADP
biomedich-167	50	19	malaria	malaria	ADJ
biomedich-167	50	20	induction	induction	NOUN
biomedich-167	50	21	in	in	ADP
biomedich-167	50	22	the	the	DET
biomedich-167	50	23	experimental	experimental	ADJ
biomedich-167	50	24	mice	mouse	NOUN
biomedich-167	50	25	.	.	PUNCT
biomedich-167	51	1	p.	p.	NOUN
biomedich-167	51	2	berghei	berghei	PROPN
biomedich-167	51	3	was	be	AUX
biomedich-167	51	4	obtained	obtain	VERB
biomedich-167	51	5	from	from	ADP
biomedich-167	51	6	malaria	malaria	NOUN
biomedich-167	51	7	research	research	NOUN
biomedich-167	51	8	laboratory	laboratory	NOUN
biomedich-167	51	9	,	,	PUNCT
biomedich-167	51	10	centre	centre	NOUN
biomedich-167	51	11	for	for	ADP
biomedich-167	51	12	malaria	malaria	NOUN
biomedich-167	51	13	research	research	NOUN
biomedich-167	51	14	and	and	CCONJ
biomedich-167	51	15	phytomedicine	phytomedicine	NOUN
biomedich-167	51	16	,	,	PUNCT
biomedich-167	51	17	university	university	NOUN
biomedich-167	51	18	of	of	ADP
biomedich-167	51	19	portharcourt	portharcourt	PROPN
biomedich-167	51	20	,	,	PUNCT
biomedich-167	51	21	rivers	river	NOUN
biomedich-167	51	22	state	state	PROPN
biomedich-167	51	23	,	,	PUNCT
biomedich-167	51	24	nigeria	nigeria	PROPN
biomedich-167	51	25	.	.	PUNCT
biomedich-167	52	1	mice	mouse	NOUN
biomedich-167	52	2	previously	previously	ADV
biomedich-167	52	3	infected	infect	VERB
biomedich-167	52	4	with	with	ADP
biomedich-167	52	5	p.	p.	PROPN
biomedich-167	52	6	berghei	berghei	PROPN
biomedich-167	52	7	were	be	AUX
biomedich-167	52	8	used	use	VERB
biomedich-167	52	9	as	as	ADP
biomedich-167	52	10	donor	donor	NOUN
biomedich-167	52	11	mice	mouse	NOUN
biomedich-167	52	12	and	and	CCONJ
biomedich-167	52	13	parasites	parasite	NOUN
biomedich-167	52	14	were	be	AUX
biomedich-167	52	15	kept	keep	VERB
biomedich-167	52	16	alive	alive	ADJ
biomedich-167	52	17	by	by	ADP
biomedich-167	52	18	continuous	continuous	ADJ
biomedich-167	52	19	intraperitoneal	intraperitoneal	NOUN
biomedich-167	52	20	(	(	PUNCT
biomedich-167	52	21	i.p	i.p	NOUN
biomedich-167	52	22	)	)	PUNCT
biomedich-167	52	23	passage	passage	NOUN
biomedich-167	52	24	of	of	ADP
biomedich-167	52	25	blood	blood	NOUN
biomedich-167	52	26	from	from	ADP
biomedich-167	52	27	donor	donor	NOUN
biomedich-167	52	28	mice	mouse	NOUN
biomedich-167	52	29	to	to	ADP
biomedich-167	52	30	uninfected	uninfected	ADJ
biomedich-167	52	31	mice	mouse	NOUN
biomedich-167	52	32	weekly	weekly	ADV
biomedich-167	52	33	.	.	PUNCT
biomedich-167	53	1	percentage	percentage	NOUN
biomedich-167	53	2	parasitemia	parasitemia	NOUN
biomedich-167	53	3	was	be	AUX
biomedich-167	53	4	determined	determine	VERB
biomedich-167	53	5	using	use	VERB
biomedich-167	53	6	the	the	DET
biomedich-167	53	7	formula	formula	NOUN
biomedich-167	53	8	below	below	ADV
biomedich-167	53	9	.	.	PUNCT
biomedich-167	54	1	protocol	protocol	NOUN
biomedich-167	54	2	for	for	ADP
biomedich-167	54	3	antiplasmodial	antiplasmodial	ADJ
biomedich-167	54	4	test	test	NOUN
biomedich-167	54	5			X
biomedich-167	54	6	protocol	protocol	NOUN
biomedich-167	54	7	for	for	ADP
biomedich-167	54	8	curative	curative	ADJ
biomedich-167	54	9	test	test	NOUN
biomedich-167	54	10	the	the	DET
biomedich-167	54	11	curative	curative	ADJ
biomedich-167	54	12	test	test	NOUN
biomedich-167	54	13	was	be	AUX
biomedich-167	54	14	performed	perform	VERB
biomedich-167	54	15	as	as	SCONJ
biomedich-167	54	16	described	describe	VERB
biomedich-167	54	17	by	by	ADP
biomedich-167	54	18	ryley	ryley	NOUN
biomedich-167	54	19	and	and	CCONJ
biomedich-167	54	20	peters	peters	PROPN
biomedich-167	54	21	(	(	PUNCT
biomedich-167	54	22	1970	1970	NUM
biomedich-167	54	23	)	)	PUNCT
biomedich-167	54	24	.	.	PUNCT
biomedich-167	55	1	thirty	thirty	NUM
biomedich-167	55	2	mice	mouse	NOUN
biomedich-167	55	3	randomly	randomly	ADV
biomedich-167	55	4	grouped	group	VERB
biomedich-167	55	5	into	into	ADP
biomedich-167	55	6	6	6	NUM
biomedich-167	55	7	(	(	PUNCT
biomedich-167	55	8	a1	a1	NOUN
biomedich-167	55	9	-	-	PUNCT
biomedich-167	55	10	a6	a6	NOUN
biomedich-167	55	11	)	)	PUNCT
biomedich-167	55	12	of	of	ADP
biomedich-167	55	13	5	5	NUM
biomedich-167	55	14	mice	mouse	NOUN
biomedich-167	55	15	each	each	PRON
biomedich-167	55	16	were	be	AUX
biomedich-167	55	17	used	use	VERB
biomedich-167	55	18	.	.	PUNCT
biomedich-167	56	1	group	group	NOUN
biomedich-167	56	2	a1	a1	NOUN
biomedich-167	56	3	served	serve	VERB
biomedich-167	56	4	as	as	ADP
biomedich-167	56	5	the	the	DET
biomedich-167	56	6	normal	normal	ADJ
biomedich-167	56	7	control	control	NOUN
biomedich-167	56	8	while	while	SCONJ
biomedich-167	56	9	a2	a2	NOUN
biomedich-167	56	10	-	-	PUNCT
biomedich-167	56	11	a6	a6	NOUN
biomedich-167	56	12	,	,	PUNCT
biomedich-167	56	13	which	which	PRON
biomedich-167	56	14	served	serve	VERB
biomedich-167	56	15	as	as	SCONJ
biomedich-167	56	16	the	the	DET
biomedich-167	56	17	experimental	experimental	ADJ
biomedich-167	56	18	groups	group	NOUN
biomedich-167	56	19	were	be	AUX
biomedich-167	56	20	inoculated	inoculate	VERB
biomedich-167	56	21	with	with	ADP
biomedich-167	56	22	1	1	NUM
biomedich-167	56	23	×	×	NOUN
biomedich-167	56	24	107	107	NUM
biomedich-167	56	25	p.	p.	NOUN
biomedich-167	56	26	berghei	berghei	NOUN
biomedich-167	56	27	-	-	PUNCT
biomedich-167	56	28	infected	infect	VERB
biomedich-167	56	29	blood	blood	NOUN
biomedich-167	56	30	(	(	PUNCT
biomedich-167	56	31	i.p	i.p	PROPN
biomedich-167	56	32	)	)	PUNCT
biomedich-167	56	33	.	.	PUNCT
biomedich-167	57	1	three	three	NUM
biomedich-167	57	2	days	day	NOUN
biomedich-167	57	3	later	later	ADV
biomedich-167	57	4	,	,	PUNCT
biomedich-167	57	5	the	the	DET
biomedich-167	57	6	mice	mouse	NOUN
biomedich-167	57	7	were	be	AUX
biomedich-167	57	8	treated	treat	VERB
biomedich-167	57	9	orally	orally	ADV
biomedich-167	57	10	as	as	SCONJ
biomedich-167	57	11	follows	follow	VERB
biomedich-167	57	12	:	:	PUNCT
biomedich-167	57	13	group	group	NOUN
biomedich-167	57	14	a1	a1	NOUN
biomedich-167	57	15	(	(	PUNCT
biomedich-167	57	16	normal	normal	ADJ
biomedich-167	57	17	control	control	NOUN
biomedich-167	57	18	)	)	PUNCT
biomedich-167	57	19	was	be	AUX
biomedich-167	57	20	treated	treat	VERB
biomedich-167	57	21	with	with	ADP
biomedich-167	57	22	normal	normal	ADJ
biomedich-167	57	23	saline	saline	NOUN
biomedich-167	57	24	(	(	PUNCT
biomedich-167	57	25	0.2ml	0.2ml	NUM
biomedich-167	57	26	)	)	PUNCT
biomedich-167	57	27	daily	daily	ADV
biomedich-167	57	28	for	for	ADP
biomedich-167	57	29	4	4	NUM
biomedich-167	57	30	days	day	NOUN
biomedich-167	57	31	.	.	PUNCT
biomedich-167	58	1	group	group	NOUN
biomedich-167	58	2	a2	a2	PROPN
biomedich-167	58	3	(	(	PUNCT
biomedich-167	58	4	negative	negative	ADJ
biomedich-167	58	5	control	control	NOUN
biomedich-167	58	6	)	)	PUNCT
biomedich-167	58	7	and	and	CCONJ
biomedich-167	58	8	group	group	NOUN
biomedich-167	58	9	a3	a3	NOUN
biomedich-167	58	10	(	(	PUNCT
biomedich-167	58	11	positive	positive	ADJ
biomedich-167	58	12	control	control	NOUN
biomedich-167	58	13	)	)	PUNCT
biomedich-167	58	14	were	be	AUX
biomedich-167	58	15	treated	treat	VERB
biomedich-167	58	16	with	with	ADP
biomedich-167	58	17	normal	normal	ADJ
biomedich-167	58	18	saline	saline	NOUN
biomedich-167	58	19	(	(	PUNCT
biomedich-167	58	20	0.2ml	0.2ml	NUM
biomedich-167	58	21	)	)	PUNCT
biomedich-167	58	22	and	and	CCONJ
biomedich-167	58	23	cq	cq	PROPN
biomedich-167	58	24	(	(	PUNCT
biomedich-167	58	25	10mg	10mg	PROPN
biomedich-167	58	26	/	/	SYM
biomedich-167	58	27	kg	kg	NOUN
biomedich-167	58	28	)	)	PUNCT
biomedich-167	58	29	daily	daily	ADV
biomedich-167	58	30	for	for	ADP
biomedich-167	58	31	4	4	NUM
biomedich-167	58	32	days	day	NOUN
biomedich-167	58	33	,	,	PUNCT
biomedich-167	58	34	respectively	respectively	ADV
biomedich-167	58	35	.	.	PUNCT
biomedich-167	59	1	groups	group	NOUN
biomedich-167	59	2	a4	a4	NOUN
biomedich-167	59	3	-	-	PUNCT
biomedich-167	59	4	a6	a6	NOUN
biomedich-167	59	5	were	be	AUX
biomedich-167	59	6	treated	treat	VERB
biomedich-167	59	7	with	with	ADP
biomedich-167	59	8	d	d	PROPN
biomedich-167	59	9	(	(	PUNCT
biomedich-167	59	10	2.2mg	2.2mg	PROPN
biomedich-167	59	11	/	/	SYM
biomedich-167	59	12	kg	kg	NOUN
biomedich-167	59	13	)	)	PUNCT
biomedich-167	59	14	,	,	PUNCT
biomedich-167	59	15	a	a	X
biomedich-167	59	16	/	/	SYM
biomedich-167	59	17	l	l	NOUN
biomedich-167	59	18	(	(	PUNCT
biomedich-167	59	19	2.3/13.7	2.3/13.7	NUM
biomedich-167	59	20	mg	mg	PROPN
biomedich-167	59	21	/	/	SYM
biomedich-167	59	22	kg	kg	PROPN
biomedich-167	59	23	)	)	PUNCT
biomedich-167	59	24	and	and	CCONJ
biomedich-167	59	25	a	a	DET
biomedich-167	59	26	/	/	SYM
biomedich-167	59	27	l	l	NOUN
biomedich-167	59	28	/	/	SYM
biomedich-167	59	29	d	d	NOUN
biomedich-167	59	30	daily	daily	ADV
biomedich-167	59	31	for	for	ADP
biomedich-167	59	32	4	4	NUM
biomedich-167	59	33	days	day	NOUN
biomedich-167	59	34	,	,	PUNCT
biomedich-167	59	35	respectively	respectively	ADV
biomedich-167	59	36	.	.	PUNCT
biomedich-167	60	1	on	on	ADP
biomedich-167	60	2	day	day	NOUN
biomedich-167	60	3	5	5	NUM
biomedich-167	60	4	,	,	PUNCT
biomedich-167	60	5	tail	tail	NOUN
biomedich-167	60	6	blood	blood	NOUN
biomedich-167	60	7	samples	sample	NOUN
biomedich-167	60	8	were	be	AUX
biomedich-167	60	9	collected	collect	VERB
biomedich-167	60	10	from	from	ADP
biomedich-167	60	11	the	the	DET
biomedich-167	60	12	mice	mouse	NOUN
biomedich-167	60	13	and	and	CCONJ
biomedich-167	60	14	thin	thin	ADJ
biomedich-167	60	15	smears	smear	NOUN
biomedich-167	60	16	were	be	AUX
biomedich-167	60	17	prepared	prepare	VERB
biomedich-167	60	18	on	on	ADP
biomedich-167	60	19	slides	slide	NOUN
biomedich-167	60	20	and	and	CCONJ
biomedich-167	60	21	stained	stain	VERB
biomedich-167	60	22	with	with	ADP
biomedich-167	60	23	10	10	NUM
biomedich-167	60	24	%	%	NOUN
biomedich-167	60	25	giemsa	giemsa	NOUN
biomedich-167	60	26	stain	stain	NOUN
biomedich-167	60	27	.	.	PUNCT
biomedich-167	61	1	the	the	DET
biomedich-167	61	2	stained	stain	VERB
biomedich-167	61	3	slides	slide	NOUN
biomedich-167	61	4	were	be	AUX
biomedich-167	61	5	examined	examine	VERB
biomedich-167	61	6	microscopically	microscopically	ADV
biomedich-167	61	7	with	with	ADP
biomedich-167	61	8	an	an	DET
biomedich-167	61	9	oil	oil	NOUN
biomedich-167	61	10	immersion	immersion	NOUN
biomedich-167	61	11	objective	objective	NOUN
biomedich-167	61	12	of	of	ADP
biomedich-167	61	13	100×	100×	PROPN
biomedich-167	61	14	magnification	magnification	NOUN
biomedich-167	61	15	power	power	NOUN
biomedich-167	61	16	.	.	PUNCT
biomedich-167	62	1	the	the	DET
biomedich-167	62	2	percentage	percentage	NOUN
biomedich-167	62	3	parasitemia	parasitemia	NOUN
biomedich-167	62	4	and	and	CCONJ
biomedich-167	62	5	inhibitions	inhibition	NOUN
biomedich-167	62	6	were	be	AUX
biomedich-167	62	7	calculated	calculate	VERB
biomedich-167	62	8	using	use	VERB
biomedich-167	62	9	the	the	DET
biomedich-167	62	10	formula	formula	NOUN
biomedich-167	62	11	shown	show	VERB
biomedich-167	62	12	below	below	ADV
biomedich-167	62	13	.	.	PUNCT
biomedich-167	63	1	%	%	INTJ
biomedich-167	64	1	𝑃𝑎𝑟𝑎𝑠𝑖𝑡𝑎𝑒𝑚𝑖𝑎	𝑃𝑎𝑟𝑎𝑠𝑖𝑡𝑎𝑒𝑚𝑖𝑎	PROPN
biomedich-167	64	2	=	=	SYM
biomedich-167	64	3	𝑁𝑢𝑚𝑏𝑒𝑟	𝑁𝑢𝑚𝑏𝑒𝑟	PROPN
biomedich-167	64	4	𝑜𝑓	𝑜𝑓	ADP
biomedich-167	64	5	𝑝𝑎𝑟𝑎𝑠𝑖𝑡𝑖𝑧𝑒𝑑	𝑝𝑎𝑟𝑎𝑠𝑖𝑡𝑖𝑧𝑒𝑑	NOUN
biomedich-167	64	6	𝑟𝑒𝑑	𝑟𝑒𝑑	NOUN
biomedich-167	64	7	𝑏𝑙𝑜𝑜𝑑	𝑏𝑙𝑜𝑜𝑑	NOUN
biomedich-167	64	8	𝑐𝑒𝑙𝑙𝑠	𝑐𝑒𝑙𝑙𝑠	NOUN
biomedich-167	64	9	(	(	PUNCT
biomedich-167	64	10	𝑅𝐵𝐶𝑠	𝑅𝐵𝐶𝑠	PROPN
biomedich-167	64	11	)	)	PUNCT
biomedich-167	64	12	total	total	ADJ
biomedich-167	64	13	number	number	NOUN
biomedich-167	64	14	of	of	ADP
biomedich-167	64	15	rbcs	rbc	NOUN
biomedich-167	64	16	count	count	VERB
biomedich-167	64	17	×	×	NOUN
biomedich-167	64	18	100	100	NUM
biomedich-167	64	19	%	%	NOUN
biomedich-167	64	20	%	%	NOUN
biomedich-167	64	21	𝐼𝑛ℎ𝑖𝑏𝑖𝑡𝑖𝑜𝑛	𝐼𝑛ℎ𝑖𝑏𝑖𝑡𝑖𝑜𝑛	PROPN
biomedich-167	64	22	=	=	PUNCT
biomedich-167	65	1	(	(	PUNCT
biomedich-167	65	2	%	%	INTJ
biomedich-167	65	3	parasitemia	parasitemia	NOUN
biomedich-167	65	4	of	of	ADP
biomedich-167	65	5	negative	negative	ADJ
biomedich-167	65	6	control	control	NOUN
biomedich-167	65	7	−	−	NOUN
biomedich-167	65	8	%	%	NOUN
biomedich-167	65	9	parasitemia	parasitemia	NOUN
biomedich-167	65	10	of	of	ADP
biomedich-167	65	11	treated	treat	VERB
biomedich-167	65	12	group	group	NOUN
biomedich-167	65	13	)	)	PUNCT
biomedich-167	65	14	×	×	NOUN
biomedich-167	65	15	100	100	NUM
biomedich-167	65	16	%	%	NOUN
biomedich-167	65	17	parasitemia	parasitemia	NOUN
biomedich-167	65	18	of	of	ADP
biomedich-167	65	19	negative	negative	ADJ
biomedich-167	65	20	control	control	NOUN
biomedich-167	65	21			PROPN
biomedich-167	65	22	protocol	protocol	NOUN
biomedich-167	65	23	for	for	ADP
biomedich-167	65	24	suppressive	suppressive	ADJ
biomedich-167	65	25	test	test	NOUN
biomedich-167	65	26	the	the	DET
biomedich-167	65	27	suppressive	suppressive	ADJ
biomedich-167	65	28	test	test	NOUN
biomedich-167	65	29	was	be	AUX
biomedich-167	65	30	performed	perform	VERB
biomedich-167	65	31	as	as	SCONJ
biomedich-167	65	32	described	describe	VERB
biomedich-167	65	33	by	by	ADP
biomedich-167	65	34	knight	knight	NOUN
biomedich-167	65	35	and	and	CCONJ
biomedich-167	65	36	peters	peters	PROPN
biomedich-167	65	37	(	(	PUNCT
biomedich-167	65	38	1980	1980	NUM
biomedich-167	65	39	)	)	PUNCT
biomedich-167	65	40	.	.	PUNCT
biomedich-167	66	1	twenty	twenty	NUM
biomedich-167	66	2	-	-	PUNCT
biomedich-167	66	3	five	five	NUM
biomedich-167	66	4	adult	adult	NOUN
biomedich-167	66	5	swiss	swiss	ADJ
biomedich-167	66	6	albino	albino	NOUN
biomedich-167	66	7	mice	mouse	NOUN
biomedich-167	66	8	were	be	AUX
biomedich-167	66	9	inoculated	inoculate	VERB
biomedich-167	66	10	with	with	ADP
biomedich-167	66	11	blood	blood	NOUN
biomedich-167	66	12	containing	contain	VERB
biomedich-167	66	13	1	1	NUM
biomedich-167	66	14	×	×	NOUN
biomedich-167	66	15	107p	107p	PROPN
biomedich-167	66	16	.	.	PUNCT
biomedich-167	67	1	berghei	berghei	PROPN
biomedich-167	67	2	and	and	CCONJ
biomedich-167	67	3	randomized	randomize	VERB
biomedich-167	67	4	into	into	ADP
biomedich-167	67	5	5	5	NUM
biomedich-167	67	6	groups	group	NOUN
biomedich-167	67	7	(	(	PUNCT
biomedich-167	67	8	b1	b1	NOUN
biomedich-167	67	9	-	-	PUNCT
biomedich-167	67	10	b5	b5	PROPN
biomedich-167	67	11	)	)	PUNCT
biomedich-167	67	12	of	of	ADP
biomedich-167	67	13	5	5	NUM
biomedich-167	67	14	mice	mouse	NOUN
biomedich-167	67	15	each	each	PRON
biomedich-167	67	16	.	.	PUNCT
biomedich-167	68	1	the	the	DET
biomedich-167	68	2	mice	mouse	NOUN
biomedich-167	68	3	were	be	AUX
biomedich-167	68	4	treated	treat	VERB
biomedich-167	68	5	after	after	ADP
biomedich-167	68	6	3	3	NUM
biomedich-167	68	7	hours	hour	NOUN
biomedich-167	68	8	of	of	ADP
biomedich-167	68	9	georgewill	georgewill	PROPN
biomedich-167	68	10	&	&	CCONJ
biomedich-167	68	11	adikwu	adikwu	PROPN
biomedich-167	68	12	–	–	PUNCT
biomedich-167	68	13	potential	potential	ADJ
biomedich-167	68	14	antimalarial	antimalarial	ADJ
biomedich-167	68	15	activity	activity	NOUN
biomedich-167	68	16	of	of	ADP
biomedich-167	68	17	artemether	artemether	ADJ
biomedich-167	68	18	/	/	SYM
biomedich-167	68	19	lumefantrine	lumefantrine	ADJ
biomedich-167	68	20	/	/	SYM
biomedich-167	68	21	doxycycline	doxycycline	NOUN
biomedich-167	68	22	:	:	PUNCT
biomedich-167	68	23	…	…	PUNCT
biomedich-167	68	24	3	3	NUM
biomedich-167	68	25	inoculation	inoculation	NOUN
biomedich-167	68	26	as	as	SCONJ
biomedich-167	68	27	follows	follow	VERB
biomedich-167	68	28	:	:	PUNCT
biomedich-167	68	29	group	group	NOUN
biomedich-167	68	30	b1	b1	NOUN
biomedich-167	68	31	(	(	PUNCT
biomedich-167	68	32	negative	negative	ADJ
biomedich-167	68	33	control	control	NOUN
biomedich-167	68	34	)	)	PUNCT
biomedich-167	68	35	and	and	CCONJ
biomedich-167	68	36	group	group	NOUN
biomedich-167	68	37	b2	b2	NOUN
biomedich-167	68	38	(	(	PUNCT
biomedich-167	68	39	positive	positive	ADJ
biomedich-167	68	40	control	control	NOUN
biomedich-167	68	41	)	)	PUNCT
biomedich-167	68	42	were	be	AUX
biomedich-167	68	43	orally	orally	ADV
biomedich-167	68	44	treated	treat	VERB
biomedich-167	68	45	daily	daily	ADV
biomedich-167	68	46	with	with	ADP
biomedich-167	68	47	normal	normal	ADJ
biomedich-167	68	48	saline	saline	NOUN
biomedich-167	68	49	(	(	PUNCT
biomedich-167	68	50	0.2ml	0.2ml	NUM
biomedich-167	68	51	)	)	PUNCT
biomedich-167	68	52	and	and	CCONJ
biomedich-167	68	53	cq	cq	PROPN
biomedich-167	68	54	(	(	PUNCT
biomedich-167	68	55	10mg	10mg	PROPN
biomedich-167	68	56	/	/	SYM
biomedich-167	68	57	kg	kg	PROPN
biomedich-167	68	58	)	)	PUNCT
biomedich-167	68	59	,	,	PUNCT
biomedich-167	68	60	for	for	ADP
biomedich-167	68	61	4	4	NUM
biomedich-167	68	62	days	day	NOUN
biomedich-167	68	63	,	,	PUNCT
biomedich-167	68	64	respectively	respectively	ADV
biomedich-167	68	65	.	.	PUNCT
biomedich-167	69	1	groups	group	NOUN
biomedich-167	69	2	b3	b3	PROPN
biomedich-167	69	3	-	-	PUNCT
biomedich-167	69	4	b5	b5	PROPN
biomedich-167	69	5	were	be	AUX
biomedich-167	69	6	orally	orally	ADV
biomedich-167	69	7	treated	treat	VERB
biomedich-167	69	8	with	with	ADP
biomedich-167	69	9	d	d	PROPN
biomedich-167	69	10	(	(	PUNCT
biomedich-167	69	11	2.2mg	2.2mg	PROPN
biomedich-167	69	12	/	/	SYM
biomedich-167	69	13	kg	kg	NOUN
biomedich-167	69	14	)	)	PUNCT
biomedich-167	69	15	,	,	PUNCT
biomedich-167	69	16	a	a	X
biomedich-167	69	17	/	/	SYM
biomedich-167	69	18	l	l	NOUN
biomedich-167	69	19	(	(	PUNCT
biomedich-167	69	20	2.3/13.7	2.3/13.7	NUM
biomedich-167	69	21	mg	mg	PROPN
biomedich-167	69	22	/	/	SYM
biomedich-167	69	23	kg	kg	PROPN
biomedich-167	69	24	)	)	PUNCT
biomedich-167	69	25	and	and	CCONJ
biomedich-167	69	26	a	a	DET
biomedich-167	69	27	/	/	SYM
biomedich-167	69	28	l	l	NOUN
biomedich-167	69	29	/	/	SYM
biomedich-167	69	30	d	d	NOUN
biomedich-167	69	31	daily	daily	ADV
biomedich-167	69	32	for	for	ADP
biomedich-167	69	33	4	4	NUM
biomedich-167	69	34	days	day	NOUN
biomedich-167	69	35	,	,	PUNCT
biomedich-167	69	36	respectively	respectively	ADV
biomedich-167	69	37	.	.	PUNCT
biomedich-167	70	1	on	on	ADP
biomedich-167	70	2	day	day	NOUN
biomedich-167	70	3	5	5	NUM
biomedich-167	70	4	,	,	PUNCT
biomedich-167	70	5	tail	tail	NOUN
biomedich-167	70	6	blood	blood	NOUN
biomedich-167	70	7	samples	sample	NOUN
biomedich-167	70	8	were	be	AUX
biomedich-167	70	9	collected	collect	VERB
biomedich-167	70	10	from	from	ADP
biomedich-167	70	11	the	the	DET
biomedich-167	70	12	mice	mouse	NOUN
biomedich-167	70	13	and	and	CCONJ
biomedich-167	70	14	thin	thin	ADJ
biomedich-167	70	15	smears	smear	NOUN
biomedich-167	70	16	were	be	AUX
biomedich-167	70	17	prepared	prepare	VERB
biomedich-167	70	18	on	on	ADP
biomedich-167	70	19	slides	slide	NOUN
biomedich-167	70	20	and	and	CCONJ
biomedich-167	70	21	stained	stain	VERB
biomedich-167	70	22	with	with	ADP
biomedich-167	70	23	10	10	NUM
biomedich-167	70	24	%	%	NOUN
biomedich-167	70	25	giemsa	giemsa	NOUN
biomedich-167	70	26	stain	stain	NOUN
biomedich-167	70	27	.	.	PUNCT
biomedich-167	71	1	the	the	DET
biomedich-167	71	2	stained	stain	VERB
biomedich-167	71	3	slides	slide	NOUN
biomedich-167	71	4	were	be	AUX
biomedich-167	71	5	examined	examine	VERB
biomedich-167	71	6	microscopically	microscopically	ADV
biomedich-167	71	7	with	with	ADP
biomedich-167	71	8	an	an	DET
biomedich-167	71	9	oil	oil	NOUN
biomedich-167	71	10	immersion	immersion	NOUN
biomedich-167	71	11	objective	objective	NOUN
biomedich-167	71	12	of	of	ADP
biomedich-167	71	13	100×magnification	100×magnification	NUM
biomedich-167	71	14	power	power	NOUN
biomedich-167	71	15	.	.	PUNCT
biomedich-167	72	1	the	the	DET
biomedich-167	72	2	percentage	percentage	NOUN
biomedich-167	72	3	parasitemia	parasitemia	NOUN
biomedich-167	72	4	and	and	CCONJ
biomedich-167	72	5	inhibitions	inhibition	NOUN
biomedich-167	72	6	were	be	AUX
biomedich-167	72	7	calculated	calculate	VERB
biomedich-167	72	8	as	as	SCONJ
biomedich-167	72	9	explained	explain	VERB
biomedich-167	72	10	above	above	ADV
biomedich-167	72	11	.	.	PUNCT
biomedich-167	73	1			PART
biomedich-167	74	1	protocol	protocol	NOUN
biomedich-167	74	2	for	for	ADP
biomedich-167	74	3	prophylactic	prophylactic	ADJ
biomedich-167	74	4	test	test	NOUN
biomedich-167	74	5	the	the	DET
biomedich-167	74	6	prophylactic	prophylactic	ADJ
biomedich-167	74	7	test	test	NOUN
biomedich-167	74	8	was	be	AUX
biomedich-167	74	9	performed	perform	VERB
biomedich-167	74	10	as	as	SCONJ
biomedich-167	74	11	described	describe	VERB
biomedich-167	74	12	by	by	ADP
biomedich-167	74	13	peters	peters	PROPN
biomedich-167	74	14	(	(	PUNCT
biomedich-167	74	15	1965	1965	NUM
biomedich-167	74	16	)	)	PUNCT
biomedich-167	74	17	.	.	PUNCT
biomedich-167	75	1	twenty	twenty	NUM
biomedich-167	75	2	-	-	PUNCT
biomedich-167	75	3	five	five	NUM
biomedich-167	75	4	adult	adult	NOUN
biomedich-167	75	5	swiss	swiss	ADJ
biomedich-167	75	6	albino	albino	NOUN
biomedich-167	75	7	mice	mouse	NOUN
biomedich-167	75	8	randomized	randomize	VERB
biomedich-167	75	9	into	into	ADP
biomedich-167	75	10	5	5	NUM
biomedich-167	75	11	groups	group	NOUN
biomedich-167	75	12	(	(	PUNCT
biomedich-167	75	13	c1	c1	PROPN
biomedich-167	75	14	-	-	PUNCT
biomedich-167	75	15	c5	c5	PROPN
biomedich-167	75	16	)	)	PUNCT
biomedich-167	75	17	of	of	ADP
biomedich-167	75	18	5	5	NUM
biomedich-167	75	19	mice	mouse	NOUN
biomedich-167	75	20	/	/	SYM
biomedich-167	75	21	group	group	NOUN
biomedich-167	75	22	were	be	AUX
biomedich-167	75	23	orally	orally	ADV
biomedich-167	75	24	treated	treat	VERB
biomedich-167	75	25	as	as	SCONJ
biomedich-167	75	26	follows	follow	VERB
biomedich-167	75	27	:	:	PUNCT
biomedich-167	75	28	group	group	NOUN
biomedich-167	75	29	c1	c1	PROPN
biomedich-167	75	30	(	(	PUNCT
biomedich-167	75	31	negative	negative	ADJ
biomedich-167	75	32	control	control	NOUN
biomedich-167	75	33	)	)	PUNCT
biomedich-167	75	34	and	and	CCONJ
biomedich-167	75	35	group	group	NOUN
biomedich-167	75	36	c2	c2	PROPN
biomedich-167	75	37	(	(	PUNCT
biomedich-167	75	38	positive	positive	ADJ
biomedich-167	75	39	control	control	NOUN
biomedich-167	75	40	)	)	PUNCT
biomedich-167	75	41	were	be	AUX
biomedich-167	75	42	treated	treat	VERB
biomedich-167	75	43	with	with	ADP
biomedich-167	75	44	normal	normal	ADJ
biomedich-167	75	45	saline	saline	NOUN
biomedich-167	75	46	(	(	PUNCT
biomedich-167	75	47	0.2	0.2	NUM
biomedich-167	75	48	ml	ml	NOUN
biomedich-167	75	49	)	)	PUNCT
biomedich-167	75	50	and	and	CCONJ
biomedich-167	75	51	cq	cq	INTJ
biomedich-167	75	52	(	(	PUNCT
biomedich-167	75	53	10	10	NUM
biomedich-167	75	54	mg	mg	NUM
biomedich-167	75	55	/	/	SYM
biomedich-167	75	56	kg	kg	NOUN
biomedich-167	75	57	)	)	PUNCT
biomedich-167	75	58	daily	daily	ADV
biomedich-167	75	59	for	for	ADP
biomedich-167	75	60	4	4	NUM
biomedich-167	75	61	days	day	NOUN
biomedich-167	75	62	,	,	PUNCT
biomedich-167	75	63	respectively	respectively	ADV
biomedich-167	75	64	.	.	PUNCT
biomedich-167	76	1	groups	group	NOUN
biomedich-167	76	2	c3	c3	PROPN
biomedich-167	76	3	–	–	PUNCT
biomedich-167	76	4	c5	c5	PROPN
biomedich-167	76	5	were	be	AUX
biomedich-167	76	6	treated	treat	VERB
biomedich-167	76	7	with	with	ADP
biomedich-167	76	8	d	d	PROPN
biomedich-167	76	9	(	(	PUNCT
biomedich-167	76	10	2.2	2.2	NUM
biomedich-167	76	11	mg	mg	PROPN
biomedich-167	76	12	/	/	SYM
biomedich-167	76	13	kg	kg	PROPN
biomedich-167	76	14	)	)	PUNCT
biomedich-167	76	15	,	,	PUNCT
biomedich-167	76	16	a	a	X
biomedich-167	76	17	/	/	SYM
biomedich-167	76	18	l	l	NOUN
biomedich-167	76	19	(	(	PUNCT
biomedich-167	76	20	2.3/13.7	2.3/13.7	NUM
biomedich-167	76	21	mg	mg	PROPN
biomedich-167	76	22	/	/	SYM
biomedich-167	76	23	kg	kg	PROPN
biomedich-167	76	24	)	)	PUNCT
biomedich-167	76	25	,	,	PUNCT
biomedich-167	76	26	and	and	CCONJ
biomedich-167	76	27	a	a	DET
biomedich-167	76	28	/	/	SYM
biomedich-167	76	29	l	l	NOUN
biomedich-167	76	30	/	/	SYM
biomedich-167	76	31	d	d	NOUN
biomedich-167	76	32	daily	daily	ADV
biomedich-167	76	33	for	for	ADP
biomedich-167	76	34	4	4	NUM
biomedich-167	76	35	days	day	NOUN
biomedich-167	76	36	,	,	PUNCT
biomedich-167	76	37	respectively	respectively	ADV
biomedich-167	76	38	.	.	PUNCT
biomedich-167	77	1	on	on	ADP
biomedich-167	77	2	day	day	NOUN
biomedich-167	77	3	5	5	NUM
biomedich-167	77	4	,	,	PUNCT
biomedich-167	77	5	the	the	DET
biomedich-167	77	6	mice	mouse	NOUN
biomedich-167	77	7	were	be	AUX
biomedich-167	77	8	inoculated	inoculate	VERB
biomedich-167	77	9	with	with	ADP
biomedich-167	77	10	blood	blood	NOUN
biomedich-167	77	11	containing	contain	VERB
biomedich-167	77	12	1	1	NUM
biomedich-167	77	13	×	×	PROPN
biomedich-167	77	14	107	107	NUM
biomedich-167	77	15	p.	p.	NOUN
biomedich-167	77	16	berghei	berghei	PROPN
biomedich-167	77	17	.	.	PUNCT
biomedich-167	78	1	after	after	ADP
biomedich-167	78	2	2	2	NUM
biomedich-167	78	3	days	day	NOUN
biomedich-167	78	4	,	,	PUNCT
biomedich-167	78	5	tail	tail	NOUN
biomedich-167	78	6	blood	blood	NOUN
biomedich-167	78	7	samples	sample	NOUN
biomedich-167	78	8	were	be	AUX
biomedich-167	78	9	collected	collect	VERB
biomedich-167	78	10	and	and	CCONJ
biomedich-167	78	11	percentage	percentage	NOUN
biomedich-167	78	12	parasitemia	parasitemia	NOUN
biomedich-167	78	13	and	and	CCONJ
biomedich-167	78	14	inhibitions	inhibition	NOUN
biomedich-167	78	15	were	be	AUX
biomedich-167	78	16	determined	determine	VERB
biomedich-167	78	17	as	as	SCONJ
biomedich-167	78	18	explained	explain	VERB
biomedich-167	78	19	above	above	ADV
biomedich-167	78	20	.	.	PUNCT
biomedich-167	79	1	determination	determination	NOUN
biomedich-167	79	2	of	of	ADP
biomedich-167	79	3	mean	mean	ADJ
biomedich-167	79	4	survival	survival	NOUN
biomedich-167	79	5	time	time	NOUN
biomedich-167	79	6	from	from	ADP
biomedich-167	79	7	the	the	DET
biomedich-167	79	8	time	time	NOUN
biomedich-167	79	9	of	of	ADP
biomedich-167	79	10	inoculation	inoculation	NOUN
biomedich-167	79	11	with	with	ADP
biomedich-167	79	12	p.	p.	PROPN
biomedich-167	79	13	berghei	berghei	PROPN
biomedich-167	79	14	until	until	ADP
biomedich-167	79	15	death	death	NOUN
biomedich-167	79	16	,	,	PUNCT
biomedich-167	79	17	mortality	mortality	NOUN
biomedich-167	79	18	of	of	ADP
biomedich-167	79	19	each	each	DET
biomedich-167	79	20	mouse	mouse	NOUN
biomedich-167	79	21	was	be	AUX
biomedich-167	79	22	monitored	monitor	VERB
biomedich-167	79	23	and	and	CCONJ
biomedich-167	79	24	recorded	record	VERB
biomedich-167	79	25	.	.	PUNCT
biomedich-167	80	1	mean	mean	VERB
biomedich-167	80	2	survival	survival	NOUN
biomedich-167	80	3	time	time	NOUN
biomedich-167	80	4	(	(	PUNCT
biomedich-167	80	5	mst	mst	PROPN
biomedich-167	80	6	)	)	PUNCT
biomedich-167	80	7	was	be	AUX
biomedich-167	80	8	determined	determine	VERB
biomedich-167	80	9	using	use	VERB
biomedich-167	80	10	the	the	DET
biomedich-167	80	11	formula	formula	NOUN
biomedich-167	80	12	below	below	ADV
biomedich-167	80	13	.	.	PUNCT
biomedich-167	81	1	𝑀𝑆𝑇	𝑀𝑆𝑇	PROPN
biomedich-167	81	2	=	=	PUNCT
biomedich-167	81	3	𝑆𝑢𝑚	𝑆𝑢𝑚	PROPN
biomedich-167	81	4	𝑜𝑓	𝑜𝑓	ADP
biomedich-167	81	5	𝑠𝑢𝑟𝑣𝑖𝑣𝑎𝑙	𝑠𝑢𝑟𝑣𝑖𝑣𝑎𝑙	PROPN
biomedich-167	81	6	𝑡𝑖𝑚𝑒	𝑡𝑖𝑚𝑒	VERB
biomedich-167	81	7	𝑜𝑓	𝑜𝑓	ADP
biomedich-167	81	8	𝑎𝑙𝑙	𝑎𝑙𝑙	X
biomedich-167	81	9	𝑚𝑖𝑐𝑒	𝑚𝑖𝑐𝑒	NOUN
biomedich-167	81	10	𝑖𝑛	𝑖𝑛	X
biomedich-167	82	1	𝑎	𝑎	DET
biomedich-167	82	2	𝑔𝑟𝑜𝑢𝑝	𝑔𝑟𝑜𝑢𝑝	NOUN
biomedich-167	82	3	(	(	PUNCT
biomedich-167	82	4	𝐷𝑎𝑦𝑠	𝐷𝑎𝑦𝑠	PROPN
biomedich-167	82	5	)	)	PUNCT
biomedich-167	82	6	total	total	ADJ
biomedich-167	82	7	number	number	NOUN
biomedich-167	82	8	of	of	ADP
biomedich-167	82	9	mice	mouse	NOUN
biomedich-167	82	10	in	in	ADP
biomedich-167	82	11	that	that	DET
biomedich-167	82	12	group	group	NOUN
biomedich-167	82	13	evaluation	evaluation	NOUN
biomedich-167	82	14	of	of	ADP
biomedich-167	82	15	biochemical	biochemical	ADJ
biomedich-167	82	16	parameters	parameter	NOUN
biomedich-167	82	17	in	in	ADP
biomedich-167	82	18	the	the	DET
biomedich-167	82	19	curative	curative	ADJ
biomedich-167	82	20	study	study	NOUN
biomedich-167	82	21	,	,	PUNCT
biomedich-167	82	22	blood	blood	NOUN
biomedich-167	82	23	samples	sample	NOUN
biomedich-167	82	24	were	be	AUX
biomedich-167	82	25	collected	collect	VERB
biomedich-167	82	26	from	from	ADP
biomedich-167	82	27	the	the	DET
biomedich-167	82	28	mice	mouse	NOUN
biomedich-167	82	29	and	and	CCONJ
biomedich-167	82	30	evaluated	evaluate	VERB
biomedich-167	82	31	for	for	ADP
biomedich-167	82	32	red	red	ADJ
biomedich-167	82	33	blood	blood	NOUN
biomedich-167	82	34	cells	cell	NOUN
biomedich-167	82	35	(	(	PUNCT
biomedich-167	82	36	rbcs	rbc	NOUN
biomedich-167	82	37	)	)	PUNCT
biomedich-167	82	38	,	,	PUNCT
biomedich-167	82	39	hemoglobin	hemoglobin	NOUN
biomedich-167	82	40	(	(	PUNCT
biomedich-167	82	41	hb	hb	PROPN
biomedich-167	82	42	)	)	PUNCT
biomedich-167	82	43	,	,	PUNCT
biomedich-167	82	44	packed	pack	VERB
biomedich-167	82	45	cell	cell	NOUN
biomedich-167	82	46	volume	volume	NOUN
biomedich-167	82	47	(	(	PUNCT
biomedich-167	82	48	pcv	pcv	NOUN
biomedich-167	82	49	)	)	PUNCT
biomedich-167	82	50	,	,	PUNCT
biomedich-167	82	51	white	white	ADJ
biomedich-167	82	52	blood	blood	NOUN
biomedich-167	82	53	cells	cell	NOUN
biomedich-167	82	54	(	(	PUNCT
biomedich-167	82	55	wbcs	wbcs	PROPN
biomedich-167	82	56	)	)	PUNCT
biomedich-167	82	57	,	,	PUNCT
biomedich-167	82	58	total	total	ADJ
biomedich-167	82	59	cholesterol	cholesterol	NOUN
biomedich-167	82	60	(	(	PUNCT
biomedich-167	82	61	chol	chol	NOUN
biomedich-167	82	62	)	)	PUNCT
biomedich-167	82	63	,	,	PUNCT
biomedich-167	82	64	triglyceride	triglyceride	INTJ
biomedich-167	82	65	(	(	PUNCT
biomedich-167	82	66	tg	tg	INTJ
biomedich-167	82	67	)	)	PUNCT
biomedich-167	82	68	,	,	PUNCT
biomedich-167	82	69	low	low	ADJ
biomedich-167	82	70	-	-	PUNCT
biomedich-167	82	71	density	density	NOUN
biomedich-167	82	72	lipoprotein	lipoprotein	ADJ
biomedich-167	82	73	cholesterol	cholesterol	NOUN
biomedich-167	82	74	and	and	CCONJ
biomedich-167	82	75	(	(	PUNCT
biomedich-167	82	76	ldl	ldl	NOUN
biomedich-167	82	77	-	-	PUNCT
biomedich-167	82	78	c	c	NOUN
biomedich-167	82	79	)	)	PUNCT
biomedich-167	82	80	and	and	CCONJ
biomedich-167	82	81	high	high	ADJ
biomedich-167	82	82	-	-	PUNCT
biomedich-167	82	83	density	density	NOUN
biomedich-167	82	84	lipoprotein	lipoprotein	ADJ
biomedich-167	82	85	cholesterol	cholesterol	NOUN
biomedich-167	82	86	(	(	PUNCT
biomedich-167	82	87	hdl	hdl	NOUN
biomedich-167	82	88	-	-	PUNCT
biomedich-167	82	89	c	c	NOUN
biomedich-167	82	90	)	)	PUNCT
biomedich-167	82	91	using	use	VERB
biomedich-167	82	92	an	an	DET
biomedich-167	82	93	auto	auto	NOUN
biomedich-167	82	94	analyzer	analyzer	NOUN
biomedich-167	82	95	.	.	PUNCT
biomedich-167	83	1	statistical	statistical	ADJ
biomedich-167	83	2	analysis	analysis	NOUN
biomedich-167	83	3	values	value	NOUN
biomedich-167	83	4	were	be	AUX
biomedich-167	83	5	expressed	express	VERB
biomedich-167	83	6	as	as	ADP
biomedich-167	83	7	mean	mean	PROPN
biomedich-167	83	8	±	±	NUM
biomedich-167	83	9	sem	sem	NOUN
biomedich-167	83	10	(	(	PUNCT
biomedich-167	83	11	standard	standard	ADJ
biomedich-167	83	12	error	error	NOUN
biomedich-167	83	13	of	of	ADP
biomedich-167	83	14	mean	mean	NOUN
biomedich-167	83	15	)	)	PUNCT
biomedich-167	83	16	of	of	ADP
biomedich-167	83	17	n=5	n=5	PROPN
biomedich-167	83	18	.	.	PUNCT
biomedich-167	84	1	values	value	NOUN
biomedich-167	84	2	were	be	AUX
biomedich-167	84	3	analyzed	analyze	VERB
biomedich-167	84	4	using	use	VERB
biomedich-167	84	5	one	one	NUM
biomedich-167	84	6	-	-	PUNCT
biomedich-167	84	7	way	way	NOUN
biomedich-167	84	8	anova	anova	PROPN
biomedich-167	84	9	,	,	PUNCT
biomedich-167	84	10	followed	follow	VERB
biomedich-167	84	11	by	by	ADP
biomedich-167	84	12	tukey	tukey	PROPN
biomedich-167	84	13	’s	’s	PART
biomedich-167	84	14	post	post	X
biomedich-167	84	15	hoc	hoc	X
biomedich-167	84	16	test	test	NOUN
biomedich-167	84	17	.	.	PUNCT
biomedich-167	85	1	p	p	NOUN
biomedich-167	85	2	values	value	NOUN
biomedich-167	85	3	less	less	ADJ
biomedich-167	85	4	than	than	ADP
biomedich-167	85	5	0.05	0.05	NUM
biomedich-167	85	6	,	,	PUNCT
biomedich-167	85	7	0.01	0.01	NUM
biomedich-167	85	8	and	and	CCONJ
biomedich-167	85	9	0.001	0.001	NUM
biomedich-167	85	10	were	be	AUX
biomedich-167	85	11	considered	consider	VERB
biomedich-167	85	12	significant	significant	ADJ
biomedich-167	85	13	.	.	PUNCT
biomedich-167	86	1	results	result	NOUN
biomedich-167	86	2	curative	curative	VERB
biomedich-167	86	3	antiplasmodial	antiplasmodial	ADJ
biomedich-167	86	4	test	test	NOUN
biomedich-167	86	5	treatment	treatment	NOUN
biomedich-167	86	6	with	with	ADP
biomedich-167	86	7	d	d	PROPN
biomedich-167	86	8	,	,	PUNCT
biomedich-167	86	9	a	a	DET
biomedich-167	86	10	/	/	SYM
biomedich-167	86	11	l	l	NOUN
biomedich-167	86	12	,	,	PUNCT
biomedich-167	86	13	and	and	CCONJ
biomedich-167	86	14	a	a	DET
biomedich-167	86	15	/	/	SYM
biomedich-167	86	16	l	l	NOUN
biomedich-167	86	17	/	/	SYM
biomedich-167	86	18	d	d	NOUN
biomedich-167	86	19	produced	produce	VERB
biomedich-167	86	20	significant	significant	ADJ
biomedich-167	86	21	decreases	decrease	NOUN
biomedich-167	86	22	in	in	ADP
biomedich-167	86	23	percentage	percentage	NOUN
biomedich-167	86	24	parasitemia	parasitemia	NOUN
biomedich-167	86	25	at	at	ADP
biomedich-167	86	26	p<0.05	p<0.05	NOUN
biomedich-167	86	27	,	,	PUNCT
biomedich-167	86	28	p<0.01	p<0.01	PROPN
biomedich-167	86	29	and	and	CCONJ
biomedich-167	86	30	p<0.001	p<0.001	PROPN
biomedich-167	86	31	,	,	PUNCT
biomedich-167	86	32	respectively	respectively	ADV
biomedich-167	86	33	when	when	SCONJ
biomedich-167	86	34	compared	compare	VERB
biomedich-167	86	35	to	to	ADP
biomedich-167	86	36	negative	negative	ADJ
biomedich-167	86	37	control	control	NOUN
biomedich-167	86	38	(	(	PUNCT
biomedich-167	86	39	pu	pu	PROPN
biomedich-167	86	40	)	)	PUNCT
biomedich-167	86	41	(	(	PUNCT
biomedich-167	86	42	table	table	NOUN
biomedich-167	86	43	1	1	NUM
biomedich-167	86	44	)	)	PUNCT
biomedich-167	86	45	.	.	PUNCT
biomedich-167	87	1	d	d	X
biomedich-167	87	2	,	,	PUNCT
biomedich-167	87	3	a	a	DET
biomedich-167	87	4	/	/	SYM
biomedich-167	87	5	l	l	NOUN
biomedich-167	87	6	and	and	CCONJ
biomedich-167	87	7	a	a	DET
biomedich-167	87	8	/	/	SYM
biomedich-167	87	9	l	l	NOUN
biomedich-167	87	10	/	/	SYM
biomedich-167	87	11	d	d	NOUN
biomedich-167	87	12	produced	produce	VERB
biomedich-167	87	13	parasitemia	parasitemia	NOUN
biomedich-167	87	14	inhibitions	inhibition	NOUN
biomedich-167	87	15	of	of	ADP
biomedich-167	87	16	60.4	60.4	NUM
biomedich-167	87	17	%	%	NOUN
biomedich-167	87	18	,	,	PUNCT
biomedich-167	87	19	70.3	70.3	NUM
biomedich-167	87	20	%	%	NOUN
biomedich-167	87	21	,	,	PUNCT
biomedich-167	87	22	and	and	CCONJ
biomedich-167	87	23	90.0	90.0	NUM
biomedich-167	87	24	%	%	NOUN
biomedich-167	87	25	,	,	PUNCT
biomedich-167	87	26	respectively	respectively	ADV
biomedich-167	87	27	whereas	whereas	SCONJ
biomedich-167	87	28	cq	cq	NOUN
biomedich-167	87	29	produced	produce	VERB
biomedich-167	87	30	76.0	76.0	NUM
biomedich-167	87	31	%	%	NOUN
biomedich-167	87	32	parasitemia	parasitemia	NOUN
biomedich-167	87	33	inhibition	inhibition	NOUN
biomedich-167	87	34	.	.	PUNCT
biomedich-167	88	1	mst	mst	PROPN
biomedich-167	88	2	was	be	AUX
biomedich-167	88	3	significantly	significantly	ADV
biomedich-167	88	4	prolonged	prolong	VERB
biomedich-167	88	5	in	in	ADP
biomedich-167	88	6	mice	mouse	NOUN
biomedich-167	88	7	treated	treat	VERB
biomedich-167	88	8	with	with	ADP
biomedich-167	88	9	d	d	PROPN
biomedich-167	88	10	,	,	PUNCT
biomedich-167	88	11	a	a	DET
biomedich-167	88	12	/	/	SYM
biomedich-167	88	13	l	l	NOUN
biomedich-167	88	14	,	,	PUNCT
biomedich-167	88	15	and	and	CCONJ
biomedich-167	88	16	a	a	DET
biomedich-167	88	17	/	/	SYM
biomedich-167	88	18	l	l	NOUN
biomedich-167	88	19	/	/	SYM
biomedich-167	88	20	d	d	NOUN
biomedich-167	88	21	at	at	ADP
biomedich-167	88	22	p<0.05	p<0.05	NOUN
biomedich-167	88	23	,	,	PUNCT
biomedich-167	88	24	p<0.01	p<0.01	PROPN
biomedich-167	88	25	,	,	PUNCT
biomedich-167	88	26	and	and	CCONJ
biomedich-167	88	27	p<0.001	p<0.001	PROPN
biomedich-167	88	28	,	,	PUNCT
biomedich-167	88	29	respectively	respectively	ADV
biomedich-167	88	30	when	when	SCONJ
biomedich-167	88	31	compared	compare	VERB
biomedich-167	88	32	to	to	ADP
biomedich-167	88	33	pu	pu	PROPN
biomedich-167	88	34	(	(	PUNCT
biomedich-167	88	35	table	table	NOUN
biomedich-167	88	36	1	1	NUM
biomedich-167	88	37	)	)	PUNCT
biomedich-167	88	38	.	.	PUNCT
biomedich-167	89	1	suppressive	suppressive	ADJ
biomedich-167	89	2	antiplasmodial	antiplasmodial	ADJ
biomedich-167	89	3	test	test	NOUN
biomedich-167	89	4	significant	significant	ADJ
biomedich-167	89	5	decreases	decrease	NOUN
biomedich-167	89	6	in	in	ADP
biomedich-167	89	7	percentage	percentage	NOUN
biomedich-167	89	8	parasitemia	parasitemia	NOUN
biomedich-167	89	9	levels	level	NOUN
biomedich-167	89	10	at	at	ADP
biomedich-167	89	11	p<0.5	p<0.5	NUM
biomedich-167	89	12	,	,	PUNCT
biomedich-167	89	13	p<0.01	p<0.01	PROPN
biomedich-167	89	14	and	and	CCONJ
biomedich-167	89	15	p<0.001	p<0.001	PROPN
biomedich-167	89	16	were	be	AUX
biomedich-167	89	17	produced	produce	VERB
biomedich-167	89	18	by	by	ADP
biomedich-167	89	19	d	d	PROPN
biomedich-167	89	20	,	,	PUNCT
biomedich-167	89	21	a	a	DET
biomedich-167	89	22	/	/	SYM
biomedich-167	89	23	l	l	NOUN
biomedich-167	89	24	,	,	PUNCT
biomedich-167	89	25	and	and	CCONJ
biomedich-167	89	26	a	a	DET
biomedich-167	89	27	/	/	SYM
biomedich-167	89	28	l	l	NOUN
biomedich-167	89	29	/	/	SYM
biomedich-167	89	30	d	d	NOUN
biomedich-167	89	31	,	,	PUNCT
biomedich-167	89	32	respectively	respectively	ADV
biomedich-167	89	33	when	when	SCONJ
biomedich-167	89	34	compared	compare	VERB
biomedich-167	89	35	to	to	ADP
biomedich-167	89	36	pu	pu	PROPN
biomedich-167	89	37	(	(	PUNCT
biomedich-167	89	38	table	table	NOUN
biomedich-167	89	39	2	2	NUM
biomedich-167	89	40	)	)	PUNCT
biomedich-167	89	41	.	.	PUNCT
biomedich-167	90	1	parasitemia	parasitemia	NOUN
biomedich-167	90	2	inhibitions	inhibition	NOUN
biomedich-167	90	3	,	,	PUNCT
biomedich-167	90	4	which	which	PRON
biomedich-167	90	5	represent	represent	VERB
biomedich-167	90	6	63.2	63.2	NUM
biomedich-167	90	7	%	%	NOUN
biomedich-167	90	8	,	,	PUNCT
biomedich-167	90	9	80.1	80.1	NUM
biomedich-167	90	10	%	%	NOUN
biomedich-167	90	11	,	,	PUNCT
biomedich-167	90	12	92	92	NUM
biomedich-167	90	13	.	.	PUNCT
biomedich-167	91	1	3	3	NUM
biomedich-167	91	2	%	%	NOUN
biomedich-167	91	3	and	and	CCONJ
biomedich-167	91	4	83	83	NUM
biomedich-167	91	5	.	.	NOUN
biomedich-167	92	1	6	6	NUM
biomedich-167	92	2	%	%	NOUN
biomedich-167	92	3	were	be	AUX
biomedich-167	92	4	produced	produce	VERB
biomedich-167	92	5	by	by	ADP
biomedich-167	92	6	d	d	PROPN
biomedich-167	92	7	,	,	PUNCT
biomedich-167	92	8	a	a	DET
biomedich-167	92	9	/	/	SYM
biomedich-167	92	10	l	l	NOUN
biomedich-167	92	11	,	,	PUNCT
biomedich-167	92	12	a	a	DET
biomedich-167	92	13	/	/	SYM
biomedich-167	92	14	l	l	NOUN
biomedich-167	92	15	/	/	SYM
biomedich-167	92	16	d	d	PROPN
biomedich-167	92	17	and	and	CCONJ
biomedich-167	92	18	cq	cq	NOUN
biomedich-167	92	19	,	,	PUNCT
biomedich-167	92	20	respectively	respectively	ADV
biomedich-167	92	21	(	(	PUNCT
biomedich-167	92	22	table	table	NOUN
biomedich-167	92	23	2	2	NUM
biomedich-167	92	24	)	)	PUNCT
biomedich-167	92	25	.	.	PUNCT
biomedich-167	93	1	treatment	treatment	NOUN
biomedich-167	93	2	with	with	ADP
biomedich-167	93	3	d	d	PROPN
biomedich-167	93	4	,	,	PUNCT
biomedich-167	93	5	a	a	DET
biomedich-167	93	6	/	/	SYM
biomedich-167	93	7	l	l	NOUN
biomedich-167	93	8	and	and	CCONJ
biomedich-167	93	9	a	a	DET
biomedich-167	93	10	/	/	SYM
biomedich-167	93	11	l	l	NOUN
biomedich-167	93	12	/	/	SYM
biomedich-167	93	13	d	d	NOUN
biomedich-167	93	14	significantly	significantly	ADV
biomedich-167	93	15	prolonged	prolong	VERB
biomedich-167	93	16	mst	mst	PROPN
biomedich-167	93	17	at	at	ADP
biomedich-167	93	18	p<0.5	p<0.5	NUM
biomedich-167	93	19	,	,	PUNCT
biomedich-167	93	20	p<0.01	p<0.01	PROPN
biomedich-167	93	21	,	,	PUNCT
biomedich-167	93	22	and	and	CCONJ
biomedich-167	93	23	p<0.001	p<0.001	PROPN
biomedich-167	93	24	,	,	PUNCT
biomedich-167	93	25	respectively	respectively	ADV
biomedich-167	93	26	when	when	SCONJ
biomedich-167	93	27	compared	compare	VERB
biomedich-167	93	28	to	to	ADP
biomedich-167	93	29	pu	pu	PROPN
biomedich-167	93	30	(	(	PUNCT
biomedich-167	93	31	table	table	NOUN
biomedich-167	93	32	2	2	NUM
biomedich-167	93	33	)	)	PUNCT
biomedich-167	93	34	.	.	PUNCT
biomedich-167	94	1	prophylactic	prophylactic	ADJ
biomedich-167	94	2	antiplasmodial	antiplasmodial	ADJ
biomedich-167	94	3	test	test	NOUN
biomedich-167	94	4	percentage	percentage	NOUN
biomedich-167	94	5	parasitemia	parasitemia	NOUN
biomedich-167	94	6	levels	level	NOUN
biomedich-167	94	7	were	be	AUX
biomedich-167	94	8	significantly	significantly	ADV
biomedich-167	94	9	decreased	decrease	VERB
biomedich-167	94	10	in	in	ADP
biomedich-167	94	11	mice	mouse	NOUN
biomedich-167	94	12	treated	treat	VERB
biomedich-167	94	13	with	with	ADP
biomedich-167	94	14	d	d	PROPN
biomedich-167	94	15	(	(	PUNCT
biomedich-167	94	16	p<0.05	p<0.05	NOUN
biomedich-167	94	17	)	)	PUNCT
biomedich-167	94	18	,	,	PUNCT
biomedich-167	94	19	a	a	DET
biomedich-167	94	20	/	/	SYM
biomedich-167	94	21	l	l	NOUN
biomedich-167	94	22	(	(	PUNCT
biomedich-167	94	23	p<0.01	p<0.01	PROPN
biomedich-167	94	24	)	)	PUNCT
biomedich-167	94	25	and	and	CCONJ
biomedich-167	94	26	a	a	DET
biomedich-167	94	27	/	/	SYM
biomedich-167	94	28	l	l	NOUN
biomedich-167	94	29	/	/	SYM
biomedich-167	94	30	d	d	NOUN
biomedich-167	94	31	(	(	PUNCT
biomedich-167	94	32	p<0.001	p<0.001	PROPN
biomedich-167	94	33	)	)	PUNCT
biomedich-167	94	34	when	when	SCONJ
biomedich-167	94	35	compared	compare	VERB
biomedich-167	94	36	to	to	ADP
biomedich-167	94	37	pu	pu	PROPN
biomedich-167	94	38	(	(	PUNCT
biomedich-167	94	39	table	table	NOUN
biomedich-167	94	40	3	3	NUM
biomedich-167	94	41	)	)	PUNCT
biomedich-167	94	42	.	.	PUNCT
biomedich-167	95	1	d	d	X
biomedich-167	95	2	,	,	PUNCT
biomedich-167	95	3	a	a	DET
biomedich-167	95	4	/	/	SYM
biomedich-167	95	5	l	l	NOUN
biomedich-167	95	6	and	and	CCONJ
biomedich-167	95	7	a	a	DET
biomedich-167	95	8	/	/	SYM
biomedich-167	95	9	l	l	NOUN
biomedich-167	95	10	/	/	SYM
biomedich-167	95	11	d	d	NOUN
biomedich-167	95	12	produced	produce	VERB
biomedich-167	95	13	parasitemia	parasitemia	NOUN
biomedich-167	95	14	inhibitions	inhibition	NOUN
biomedich-167	95	15	of	of	ADP
biomedich-167	95	16	65.1	65.1	NUM
biomedich-167	95	17	%	%	NOUN
biomedich-167	95	18	,	,	PUNCT
biomedich-167	95	19	82.8	82.8	NUM
biomedich-167	95	20	%	%	NOUN
biomedich-167	95	21	,	,	PUNCT
biomedich-167	95	22	and	and	CCONJ
biomedich-167	95	23	93.9	93.9	NUM
biomedich-167	95	24	%	%	NOUN
biomedich-167	95	25	,	,	PUNCT
biomedich-167	95	26	respectively	respectively	ADV
biomedich-167	95	27	whereas	whereas	SCONJ
biomedich-167	95	28	cq	cq	PROPN
biomedich-167	95	29	produced	produce	VERB
biomedich-167	95	30	86.7	86.7	NUM
biomedich-167	95	31	%	%	NOUN
biomedich-167	95	32	parasitemia	parasitemia	NOUN
biomedich-167	95	33	inhibition	inhibition	NOUN
biomedich-167	95	34	.	.	PUNCT
biomedich-167	96	1	significant	significant	ADJ
biomedich-167	96	2	prolongations	prolongation	NOUN
biomedich-167	96	3	of	of	ADP
biomedich-167	96	4	mst	mst	PROPN
biomedich-167	96	5	occurred	occur	VERB
biomedich-167	96	6	in	in	ADP
biomedich-167	96	7	mice	mouse	NOUN
biomedich-167	96	8	treated	treat	VERB
biomedich-167	96	9	with	with	ADP
biomedich-167	96	10	d	d	PROPN
biomedich-167	96	11	,	,	PUNCT
biomedich-167	96	12	a	a	DET
biomedich-167	96	13	/	/	SYM
biomedich-167	96	14	l	l	NOUN
biomedich-167	96	15	,	,	PUNCT
biomedich-167	96	16	and	and	CCONJ
biomedich-167	96	17	a	a	DET
biomedich-167	96	18	/	/	SYM
biomedich-167	96	19	l	l	NOUN
biomedich-167	96	20	/	/	SYM
biomedich-167	96	21	d	d	NOUN
biomedich-167	96	22	at	at	ADP
biomedich-167	96	23	p<0.5	p<0.5	NUM
biomedich-167	96	24	,	,	PUNCT
biomedich-167	96	25	p<0.01	p<0.01	PROPN
biomedich-167	96	26	and	and	CCONJ
biomedich-167	96	27	p<0.001	p<0.001	PROPN
biomedich-167	96	28	,	,	PUNCT
biomedich-167	96	29	respectively	respectively	ADV
biomedich-167	96	30	when	when	SCONJ
biomedich-167	96	31	compared	compare	VERB
biomedich-167	96	32	to	to	ADP
biomedich-167	96	33	pu	pu	PROPN
biomedich-167	96	34	(	(	PUNCT
biomedich-167	96	35	table	table	NOUN
biomedich-167	96	36	3	3	NUM
biomedich-167	96	37	)	)	PUNCT
biomedich-167	96	38	.	.	PUNCT
biomedich-167	97	1	hematological	hematological	NOUN
biomedich-167	97	2	and	and	CCONJ
biomedich-167	97	3	lipid	lipid	NOUN
biomedich-167	97	4	profile	profile	PROPN
biomedich-167	97	5	p.	p.	PROPN
biomedich-167	97	6	berghei	berghei	PROPN
biomedich-167	97	7	infected	infected	ADJ
biomedich-167	97	8	mice	mouse	NOUN
biomedich-167	97	9	showed	show	VERB
biomedich-167	97	10	significant	significant	ADJ
biomedich-167	97	11	(	(	PUNCT
biomedich-167	97	12	p<0.001	p<0.001	ADJ
biomedich-167	97	13	)	)	PUNCT
biomedich-167	97	14	increases	increase	NOUN
biomedich-167	97	15	in	in	ADP
biomedich-167	97	16	serum	serum	NOUN
biomedich-167	97	17	tg	tg	PROPN
biomedich-167	97	18	,	,	PUNCT
biomedich-167	97	19	chol	chol	NOUN
biomedich-167	97	20	,	,	PUNCT
biomedich-167	97	21	ldl	ldl	NOUN
biomedich-167	97	22	-	-	PUNCT
biomedich-167	97	23	c	c	PROPN
biomedich-167	97	24	and	and	CCONJ
biomedich-167	97	25	wbcs	wbc	VERB
biomedich-167	97	26	levels	level	NOUN
biomedich-167	97	27	with	with	ADP
biomedich-167	97	28	significant	significant	ADJ
biomedich-167	97	29	(	(	PUNCT
biomedich-167	97	30	p<0.001	p<0.001	PROPN
biomedich-167	97	31	)	)	PUNCT
biomedich-167	97	32	decreases	decrease	NOUN
biomedich-167	97	33	in	in	ADP
biomedich-167	97	34	serum	serum	NOUN
biomedich-167	97	35	hb	hb	PROPN
biomedich-167	97	36	,	,	PUNCT
biomedich-167	97	37	pcv	pcv	NOUN
biomedich-167	97	38	,	,	PUNCT
biomedich-167	97	39	rbcs	rbc	NOUN
biomedich-167	97	40	and	and	CCONJ
biomedich-167	97	41	hdl	hdl	PROPN
biomedich-167	97	42	-	-	PUNCT
biomedich-167	97	43	c	c	NOUN
biomedich-167	97	44	levels	level	NOUN
biomedich-167	97	45	when	when	SCONJ
biomedich-167	97	46	compared	compare	VERB
biomedich-167	97	47	to	to	ADP
biomedich-167	97	48	control	control	NOUN
biomedich-167	97	49	(	(	PUNCT
biomedich-167	97	50	tables	table	NOUN
biomedich-167	97	51	4	4	NUM
biomedich-167	97	52	and	and	CCONJ
biomedich-167	97	53	5	5	NUM
biomedich-167	97	54	)	)	PUNCT
biomedich-167	97	55	.	.	PUNCT
biomedich-167	98	1	on	on	ADP
biomedich-167	98	2	the	the	DET
biomedich-167	98	3	other	other	ADJ
biomedich-167	98	4	hand	hand	NOUN
biomedich-167	98	5	,	,	PUNCT
biomedich-167	98	6	treatment	treatment	NOUN
biomedich-167	98	7	with	with	ADP
biomedich-167	98	8	d	d	PROPN
biomedich-167	98	9	,	,	PUNCT
biomedich-167	98	10	a	a	DET
biomedich-167	98	11	/	/	SYM
biomedich-167	98	12	l	l	NOUN
biomedich-167	98	13	,	,	PUNCT
biomedich-167	98	14	and	and	CCONJ
biomedich-167	98	15	a	a	DET
biomedich-167	98	16	/	/	SYM
biomedich-167	98	17	l	l	NOUN
biomedich-167	98	18	/	/	SYM
biomedich-167	98	19	d	d	NOUN
biomedich-167	98	20	significantly	significantly	ADV
biomedich-167	98	21	decreased	decrease	VERB
biomedich-167	98	22	serum	serum	PROPN
biomedich-167	98	23	tg	tg	PROPN
biomedich-167	98	24	,	,	PUNCT
biomedich-167	98	25	chol	chol	NOUN
biomedich-167	98	26	,	,	PUNCT
biomedich-167	98	27	ldl	ldl	NOUN
biomedich-167	98	28	-	-	PUNCT
biomedich-167	98	29	c	c	PROPN
biomedich-167	98	30	,	,	PUNCT
biomedich-167	98	31	wbcs	wbc	VERB
biomedich-167	98	32	levels	level	NOUN
biomedich-167	98	33	and	and	CCONJ
biomedich-167	98	34	significantly	significantly	ADV
biomedich-167	98	35	increased	increase	VERB
biomedich-167	98	36	serum	serum	PROPN
biomedich-167	98	37	hb	hb	PROPN
biomedich-167	98	38	,	,	PUNCT
biomedich-167	98	39	pcv	pcv	NOUN
biomedich-167	98	40	,	,	PUNCT
biomedich-167	98	41	rbcs	rbc	NOUN
biomedich-167	98	42	and	and	CCONJ
biomedich-167	98	43	hdl	hdl	PROPN
biomedich-167	98	44	-	-	PUNCT
biomedich-167	98	45	c	c	PROPN
biomedich-167	98	46	levels	level	NOUN
biomedich-167	98	47	at	at	ADP
biomedich-167	98	48	p<0.05	p<0.05	PROPN
biomedich-167	98	49	,	,	PUNCT
biomedich-167	98	50	p<0.01and	p<0.01and	PROPN
biomedich-167	98	51	p<0.001	p<0.001	PROPN
biomedich-167	98	52	,	,	PUNCT
biomedich-167	98	53	respectively	respectively	ADV
biomedich-167	98	54	when	when	SCONJ
biomedich-167	98	55	compared	compare	VERB
biomedich-167	98	56	to	to	ADP
biomedich-167	98	57	pu	pu	PROPN
biomedich-167	98	58	(	(	PUNCT
biomedich-167	98	59	tables	table	NOUN
biomedich-167	98	60	4	4	NUM
biomedich-167	98	61	and	and	CCONJ
biomedich-167	98	62	5	5	NUM
biomedich-167	98	63	)	)	PUNCT
biomedich-167	98	64	.	.	PUNCT
biomedich-167	99	1	4	4	NUM
biomedich-167	99	2	biology	biology	NOUN
biomedich-167	99	3	,	,	PUNCT
biomedich-167	99	4	medicine	medicine	NOUN
biomedich-167	99	5	,	,	PUNCT
biomedich-167	99	6	&	&	CCONJ
biomedich-167	99	7	natural	natural	ADJ
biomedich-167	99	8	product	product	NOUN
biomedich-167	99	9	chemistry	chemistry	NOUN
biomedich-167	99	10	11	11	NUM
biomedich-167	99	11	(	(	PUNCT
biomedich-167	99	12	1	1	NUM
biomedich-167	99	13	)	)	PUNCT
biomedich-167	99	14	,	,	PUNCT
biomedich-167	99	15	2022	2022	NUM
biomedich-167	99	16	:	:	PUNCT
biomedich-167	99	17	1	1	NUM
biomedich-167	99	18	-	-	SYM
biomedich-167	99	19	6	6	NUM
biomedich-167	99	20	table	table	NOUN
biomedich-167	99	21	1	1	NUM
biomedich-167	99	22	.	.	PUNCT
biomedich-167	99	23	curative	curative	ADJ
biomedich-167	99	24	effect	effect	NOUN
biomedich-167	99	25	of	of	ADP
biomedich-167	99	26	artemether	artemether	ADJ
biomedich-167	99	27	/	/	SYM
biomedich-167	99	28	lumefantrine	lumefantrine	ADJ
biomedich-167	99	29	/	/	SYM
biomedich-167	99	30	doxycycline	doxycycline	NOUN
biomedich-167	99	31	on	on	ADP
biomedich-167	99	32	plasmodium	plasmodium	NOUN
biomedich-167	99	33	berghei	berghei	NOUN
biomedich-167	99	34	infected	infect	VERB
biomedich-167	99	35	mice	mouse	NOUN
biomedich-167	99	36	.	.	PUNCT
biomedich-167	100	1	data	datum	NOUN
biomedich-167	100	2	as	as	ADP
biomedich-167	100	3	mean	mean	PROPN
biomedich-167	100	4	±	±	NUM
biomedich-167	100	5	sem	sem	NOUN
biomedich-167	100	6	(	(	PUNCT
biomedich-167	100	7	standard	standard	ADJ
biomedich-167	100	8	error	error	NOUN
biomedich-167	100	9	of	of	ADP
biomedich-167	100	10	mean	mean	NOUN
biomedich-167	100	11	)	)	PUNCT
biomedich-167	100	12	n=	n=	ADJ
biomedich-167	100	13	5	5	NUM
biomedich-167	100	14	,	,	PUNCT
biomedich-167	100	15	pu	pu	PROPN
biomedich-167	100	16	:	:	PUNCT
biomedich-167	100	17	negative	negative	ADJ
biomedich-167	100	18	control	control	NOUN
biomedich-167	100	19	,	,	PUNCT
biomedich-167	100	20	cq	cq	PROPN
biomedich-167	100	21	:	:	PUNCT
biomedich-167	100	22	chloroquine	chloroquine	NOUN
biomedich-167	100	23	,	,	PUNCT
biomedich-167	100	24	d	d	NOUN
biomedich-167	100	25	:	:	PUNCT
biomedich-167	100	26	doxycycline	doxycycline	NOUN
biomedich-167	100	27	,	,	PUNCT
biomedich-167	100	28	a	a	PRON
biomedich-167	100	29	/	/	SYM
biomedich-167	100	30	l	l	NOUN
biomedich-167	100	31	:	:	PUNCT
biomedich-167	100	32	artemether	artemether	ADJ
biomedich-167	100	33	/	/	SYM
biomedich-167	100	34	lumefantrine	lumefantrine	ADJ
biomedich-167	100	35	,	,	PUNCT
biomedich-167	100	36	a	a	DET
biomedich-167	100	37	/	/	SYM
biomedich-167	100	38	l	l	NOUN
biomedich-167	100	39	/	/	SYM
biomedich-167	101	1	d	d	NOUN
biomedich-167	101	2	:	:	PUNCT
biomedich-167	101	3	artemether	artemether	ADJ
biomedich-167	101	4	/	/	SYM
biomedich-167	101	5	lumefantrine	lumefantrine	ADJ
biomedich-167	101	6	/	/	SYM
biomedich-167	101	7	doxycycline	doxycycline	NOUN
biomedich-167	101	8	,	,	PUNCT
biomedich-167	101	9	mst	mst	PROPN
biomedich-167	101	10	:	:	PUNCT
biomedich-167	101	11	mean	mean	VERB
biomedich-167	101	12	survival	survival	NOUN
biomedich-167	101	13	time	time	NOUN
biomedich-167	101	14	.	.	PUNCT
biomedich-167	102	1	ap<0.01	ap<0.01	PROPN
biomedich-167	102	2	,	,	PUNCT
biomedich-167	102	3	b	b	X
biomedich-167	102	4	p<0.05	p<0.05	NOUN
biomedich-167	102	5	,	,	PUNCT
biomedich-167	102	6	c	c	NOUN
biomedich-167	102	7	p<0.001	p<0.001	X
biomedich-167	102	8	significant	significant	ADJ
biomedich-167	102	9	difference	difference	NOUN
biomedich-167	102	10	when	when	SCONJ
biomedich-167	102	11	compared	compare	VERB
biomedich-167	102	12	to	to	ADP
biomedich-167	102	13	pu	pu	PROPN
biomedich-167	102	14	.	.	PROPN
biomedich-167	102	15	table	table	NOUN
biomedich-167	102	16	2	2	NUM
biomedich-167	102	17	.	.	PUNCT
biomedich-167	102	18	suppressive	suppressive	ADJ
biomedich-167	102	19	effect	effect	NOUN
biomedich-167	102	20	of	of	ADP
biomedich-167	102	21	artemether	artemether	ADJ
biomedich-167	102	22	/	/	SYM
biomedich-167	102	23	lumefantrine	lumefantrine	ADJ
biomedich-167	102	24	/	/	SYM
biomedich-167	102	25	doxycycline	doxycycline	NOUN
biomedich-167	102	26	on	on	ADP
biomedich-167	102	27	plasmodium	plasmodium	NOUN
biomedich-167	102	28	berghei	berghei	NOUN
biomedich-167	102	29	infected	infect	VERB
biomedich-167	102	30	mice	mouse	NOUN
biomedich-167	102	31	.	.	PUNCT
biomedich-167	103	1	treatment	treatment	NOUN
biomedich-167	103	2	%	%	NOUN
biomedich-167	103	3	parasitemia	parasitemia	NOUN
biomedich-167	103	4	%	%	NOUN
biomedich-167	103	5	inhibition	inhibition	NOUN
biomedich-167	103	6	mst	mst	PROPN
biomedich-167	103	7	(	(	PUNCT
biomedich-167	103	8	days	day	NOUN
biomedich-167	103	9	)	)	PUNCT
biomedich-167	103	10	pu	pu	PROPN
biomedich-167	103	11	20.30±1.03	20.30±1.03	NUM
biomedich-167	103	12	0.00	0.00	NUM
biomedich-167	103	13	9.66±0.45	9.66±0.45	NUM
biomedich-167	103	14	cq	cq	NOUN
biomedich-167	103	15	3.33±0.32a	3.33±0.32a	NUM
biomedich-167	103	16	83.6	83.6	NUM
biomedich-167	103	17	30.41±3.71a	30.41±3.71a	NUM
biomedich-167	104	1	d	d	NOUN
biomedich-167	104	2	7.47±0.11b	7.47±0.11b	NOUN
biomedich-167	104	3	63.2	63.2	NUM
biomedich-167	104	4	22.73±2.78b	22.73±2.78b	NUM
biomedich-167	104	5	a	a	DET
biomedich-167	104	6	/	/	SYM
biomedich-167	104	7	l	l	NOUN
biomedich-167	104	8	4.04±0.05a	4.04±0.05a	NUM
biomedich-167	104	9	80.1	80.1	NUM
biomedich-167	104	10	31.02±3.48a	31.02±3.48a	NUM
biomedich-167	104	11	a	a	DET
biomedich-167	104	12	/	/	SYM
biomedich-167	104	13	l	l	NOUN
biomedich-167	104	14	/	/	SYM
biomedich-167	104	15	d	d	SYM
biomedich-167	104	16	1.56±0.02c	1.56±0.02c	NUM
biomedich-167	104	17	92.3	92.3	NUM
biomedich-167	104	18	37.62±3.67c	37.62±3.67c	NUM
biomedich-167	104	19	data	datum	NOUN
biomedich-167	104	20	as	as	ADP
biomedich-167	104	21	mean	mean	PROPN
biomedich-167	104	22	±	±	NUM
biomedich-167	104	23	sem	sem	NOUN
biomedich-167	104	24	(	(	PUNCT
biomedich-167	104	25	standard	standard	ADJ
biomedich-167	104	26	error	error	NOUN
biomedich-167	104	27	of	of	ADP
biomedich-167	104	28	mean	mean	NOUN
biomedich-167	104	29	)	)	PUNCT
biomedich-167	104	30	n=	n=	ADJ
biomedich-167	104	31	5	5	NUM
biomedich-167	104	32	,	,	PUNCT
biomedich-167	104	33	pu	pu	PROPN
biomedich-167	104	34	:	:	PUNCT
biomedich-167	104	35	negative	negative	ADJ
biomedich-167	104	36	control	control	NOUN
biomedich-167	104	37	,	,	PUNCT
biomedich-167	104	38	cq	cq	PROPN
biomedich-167	104	39	:	:	PUNCT
biomedich-167	104	40	chloroquine	chloroquine	NOUN
biomedich-167	104	41	,	,	PUNCT
biomedich-167	104	42	d	d	NOUN
biomedich-167	104	43	:	:	PUNCT
biomedich-167	104	44	doxycycline	doxycycline	NOUN
biomedich-167	104	45	,	,	PUNCT
biomedich-167	104	46	a	a	PRON
biomedich-167	104	47	/	/	SYM
biomedich-167	104	48	l	l	NOUN
biomedich-167	104	49	:	:	PUNCT
biomedich-167	104	50	artemether	artemether	ADJ
biomedich-167	104	51	/	/	SYM
biomedich-167	104	52	lumefantrine	lumefantrine	ADJ
biomedich-167	104	53	,	,	PUNCT
biomedich-167	104	54	a	a	DET
biomedich-167	104	55	/	/	SYM
biomedich-167	104	56	l	l	NOUN
biomedich-167	104	57	/	/	SYM
biomedich-167	104	58	d	d	NOUN
biomedich-167	104	59	:	:	PUNCT
biomedich-167	104	60	artemether	artemether	ADJ
biomedich-167	104	61	/	/	SYM
biomedich-167	104	62	lumefantrine	lumefantrine	ADJ
biomedich-167	104	63	/	/	SYM
biomedich-167	104	64	doxycycline	doxycycline	NOUN
biomedich-167	104	65	,	,	PUNCT
biomedich-167	104	66	mst	mst	PROPN
biomedich-167	104	67	:	:	PUNCT
biomedich-167	104	68	mean	mean	VERB
biomedich-167	104	69	survival	survival	NOUN
biomedich-167	104	70	time	time	NOUN
biomedich-167	104	71	.	.	PUNCT
biomedich-167	105	1	ap<0.01	ap<0.01	PROPN
biomedich-167	105	2	,	,	PUNCT
biomedich-167	105	3	b	b	X
biomedich-167	105	4	p<0.05	p<0.05	NOUN
biomedich-167	105	5	,	,	PUNCT
biomedich-167	105	6	c	c	NOUN
biomedich-167	105	7	p<0.001	p<0.001	X
biomedich-167	105	8	significant	significant	ADJ
biomedich-167	105	9	difference	difference	NOUN
biomedich-167	105	10	when	when	SCONJ
biomedich-167	105	11	compared	compare	VERB
biomedich-167	105	12	to	to	ADP
biomedich-167	105	13	pu	pu	PROPN
biomedich-167	105	14	.	.	PROPN
biomedich-167	105	15	table	table	NOUN
biomedich-167	105	16	3	3	NUM
biomedich-167	105	17	.	.	PUNCT
biomedich-167	105	18	prophylactic	prophylactic	ADJ
biomedich-167	105	19	effect	effect	NOUN
biomedich-167	105	20	of	of	ADP
biomedich-167	105	21	artemether	artemether	ADJ
biomedich-167	105	22	/	/	SYM
biomedich-167	105	23	lumefantrine	lumefantrine	ADJ
biomedich-167	105	24	/	/	SYM
biomedich-167	105	25	doxycycline	doxycycline	NOUN
biomedich-167	105	26	on	on	ADP
biomedich-167	105	27	plasmodium	plasmodium	NOUN
biomedich-167	105	28	berghei	berghei	NOUN
biomedich-167	105	29	-	-	PUNCT
biomedich-167	105	30	infected	infect	VERB
biomedich-167	105	31	mice	mice	NOUN
biomedich-167	105	32	treatment	treatment	NOUN
biomedich-167	105	33	%	%	NOUN
biomedich-167	105	34	parasitemia	parasitemia	NOUN
biomedich-167	105	35	%	%	NOUN
biomedich-167	105	36	inhibition	inhibition	NOUN
biomedich-167	105	37	mst	mst	PROPN
biomedich-167	105	38	(	(	PUNCT
biomedich-167	105	39	days	day	NOUN
biomedich-167	105	40	)	)	PUNCT
biomedich-167	105	41	pu	pu	PROPN
biomedich-167	105	42	18.50±1.57	18.50±1.57	NUM
biomedich-167	106	1	0.00	0.00	NUM
biomedich-167	106	2	9.66±0.61	9.66±0.61	NUM
biomedich-167	106	3	cq	cq	NOUN
biomedich-167	106	4	2.46±0.01a	2.46±0.01a	NOUN
biomedich-167	106	5	86.7	86.7	NUM
biomedich-167	106	6	32.03±3.71a	32.03±3.71a	NUM
biomedich-167	107	1	d	d	NOUN
biomedich-167	107	2	6.46±0.35b	6.46±0.35b	NUM
biomedich-167	107	3	65.1	65.1	NUM
biomedich-167	107	4	25.52±2.60b	25.52±2.60b	NUM
biomedich-167	107	5	a	a	DET
biomedich-167	107	6	/	/	SYM
biomedich-167	107	7	l	l	NOUN
biomedich-167	107	8	2.44±0.17a	2.44±0.17a	NUM
biomedich-167	107	9	82.8	82.8	NUM
biomedich-167	107	10	32.60±3.38a	32.60±3.38a	NUM
biomedich-167	107	11	a	a	DET
biomedich-167	107	12	/	/	SYM
biomedich-167	107	13	l	l	NOUN
biomedich-167	107	14	/	/	SYM
biomedich-167	107	15	d	d	NOUN
biomedich-167	107	16	1.29±0.03c	1.29±0.03c	NUM
biomedich-167	107	17	93.9	93.9	NUM
biomedich-167	107	18	39.21±4.61c	39.21±4.61c	NUM
biomedich-167	107	19	data	datum	NOUN
biomedich-167	107	20	as	as	ADP
biomedich-167	107	21	mean	mean	PROPN
biomedich-167	107	22	±	±	NUM
biomedich-167	107	23	sem	sem	NOUN
biomedich-167	107	24	(	(	PUNCT
biomedich-167	107	25	standard	standard	ADJ
biomedich-167	107	26	error	error	NOUN
biomedich-167	107	27	of	of	ADP
biomedich-167	107	28	mean	mean	NOUN
biomedich-167	107	29	)	)	PUNCT
biomedich-167	107	30	n=	n=	ADJ
biomedich-167	107	31	5	5	X
biomedich-167	107	32	.	.	PUNCT
biomedich-167	108	1	pu	pu	ADJ
biomedich-167	108	2	:	:	PUNCT
biomedich-167	108	3	negative	negative	ADJ
biomedich-167	108	4	control	control	NOUN
biomedich-167	108	5	,	,	PUNCT
biomedich-167	108	6	cq	cq	PROPN
biomedich-167	108	7	:	:	PUNCT
biomedich-167	108	8	chloroquine	chloroquine	NOUN
biomedich-167	108	9	,	,	PUNCT
biomedich-167	108	10	d	d	NOUN
biomedich-167	108	11	:	:	PUNCT
biomedich-167	108	12	doxycycline	doxycycline	NOUN
biomedich-167	108	13	,	,	PUNCT
biomedich-167	108	14	a	a	PRON
biomedich-167	108	15	/	/	SYM
biomedich-167	108	16	l	l	NOUN
biomedich-167	108	17	:	:	PUNCT
biomedich-167	108	18	artemether	artemether	ADJ
biomedich-167	108	19	/	/	SYM
biomedich-167	108	20	lumefantrine	lumefantrine	ADJ
biomedich-167	108	21	,	,	PUNCT
biomedich-167	108	22	a	a	DET
biomedich-167	108	23	/	/	SYM
biomedich-167	108	24	l	l	NOUN
biomedich-167	108	25	/	/	SYM
biomedich-167	109	1	d	d	NOUN
biomedich-167	109	2	:	:	PUNCT
biomedich-167	109	3	artemether	artemether	ADJ
biomedich-167	109	4	/	/	SYM
biomedich-167	109	5	lumefantrine	lumefantrine	ADJ
biomedich-167	109	6	/	/	SYM
biomedich-167	109	7	doxycycline	doxycycline	NOUN
biomedich-167	109	8	,	,	PUNCT
biomedich-167	109	9	mst	mst	PROPN
biomedich-167	109	10	:	:	PUNCT
biomedich-167	109	11	mean	mean	VERB
biomedich-167	109	12	survival	survival	NOUN
biomedich-167	109	13	time	time	NOUN
biomedich-167	109	14	.	.	PUNCT
biomedich-167	110	1	ap<0.01	ap<0.01	PROPN
biomedich-167	110	2	,	,	PUNCT
biomedich-167	110	3	b	b	X
biomedich-167	110	4	p<0.05	p<0.05	NOUN
biomedich-167	110	5	,	,	PUNCT
biomedich-167	110	6	c	c	NOUN
biomedich-167	110	7	p<0.001	p<0.001	X
biomedich-167	110	8	significant	significant	ADJ
biomedich-167	110	9	difference	difference	NOUN
biomedich-167	110	10	when	when	SCONJ
biomedich-167	110	11	compared	compare	VERB
biomedich-167	110	12	to	to	ADP
biomedich-167	110	13	pu	pu	PROPN
biomedich-167	110	14	.	.	PROPN
biomedich-167	110	15	table	table	NOUN
biomedich-167	110	16	4	4	NUM
biomedich-167	110	17	.	.	PUNCT
biomedich-167	110	18	effect	effect	NOUN
biomedich-167	110	19	of	of	ADP
biomedich-167	110	20	artemether	artemether	ADJ
biomedich-167	110	21	/	/	SYM
biomedich-167	110	22	lumefantrine	lumefantrine	ADJ
biomedich-167	110	23	/	/	SYM
biomedich-167	110	24	doxycycline	doxycycline	NOUN
biomedich-167	110	25	on	on	ADP
biomedich-167	110	26	hematologic	hematologic	NOUN
biomedich-167	110	27	parameters	parameter	NOUN
biomedich-167	110	28	of	of	ADP
biomedich-167	110	29	plasmodium	plasmodium	NOUN
biomedich-167	110	30	berghei	berghei	NOUN
biomedich-167	110	31	-	-	PUNCT
biomedich-167	110	32	infected	infect	VERB
biomedich-167	110	33	mice	mouse	NOUN
biomedich-167	110	34	.	.	PUNCT
biomedich-167	111	1	treatment	treatment	NOUN
biomedich-167	111	2	rbc	rbc	PROPN
biomedich-167	111	3	(	(	PUNCT
biomedich-167	111	4	x106	x106	PROPN
biomedich-167	111	5	)	)	PUNCT
biomedich-167	111	6	wbc	wbc	PROPN
biomedich-167	111	7	(	(	PUNCT
biomedich-167	111	8	cells	cell	NOUN
biomedich-167	111	9	/	/	SYM
biomedich-167	111	10	l	l	NOUN
biomedich-167	111	11	)	)	PUNCT
biomedich-167	111	12	pcv	pcv	NOUN
biomedich-167	111	13	(	(	PUNCT
biomedich-167	111	14	%	%	INTJ
biomedich-167	111	15	)	)	PUNCT
biomedich-167	111	16	hb	hb	PROPN
biomedich-167	111	17	(	(	PUNCT
biomedich-167	111	18	g	g	PROPN
biomedich-167	111	19	/	/	SYM
biomedich-167	111	20	dl	dl	NOUN
biomedich-167	111	21	)	)	PUNCT
biomedich-167	111	22	nc	nc	PROPN
biomedich-167	111	23	5.11±0.24	5.11±0.24	NUM
biomedich-167	111	24	6.61±0.11	6.61±0.11	NUM
biomedich-167	111	25	54.63±5.00	54.63±5.00	NUM
biomedich-167	111	26	16.31±0.08	16.31±0.08	NUM
biomedich-167	111	27	pu	pu	NOUN
biomedich-167	111	28	2.41±0.29a	2.41±0.29a	NUM
biomedich-167	111	29	13.91±1.06a	13.91±1.06a	NUM
biomedich-167	111	30	20.72±3.17a	20.72±3.17a	NUM
biomedich-167	111	31	6.63±0.37a	6.63±0.37a	NUM
biomedich-167	111	32	cq	cq	NUM
biomedich-167	111	33	4.00±0.11b	4.00±0.11b	NUM
biomedich-167	111	34	9.11±0.09b	9.11±0.09b	NUM
biomedich-167	111	35	38.80±3.54b	38.80±3.54b	NUM
biomedich-167	111	36	11.93±0.15b	11.93±0.15b	NUM
biomedich-167	111	37	d	d	NOUN
biomedich-167	111	38	3.10±0.17c	3.10±0.17c	NUM
biomedich-167	111	39	10.27±0.17c	10.27±0.17c	NUM
biomedich-167	111	40	26.54±3.76c	26.54±3.76c	NOUN
biomedich-167	111	41	9.65±0.45c	9.65±0.45c	NOUN
biomedich-167	111	42	a	a	PRON
biomedich-167	111	43	/	/	SYM
biomedich-167	111	44	l	l	NOUN
biomedich-167	111	45	3.99±0.12b	3.99±0.12b	NUM
biomedich-167	111	46	9.42±0.09b	9.42±0.09b	NUM
biomedich-167	111	47	38.43±4.49b	38.43±4.49b	NUM
biomedich-167	111	48	10.04±0.80b	10.04±0.80b	NUM
biomedich-167	111	49	a	a	PRON
biomedich-167	111	50	/	/	SYM
biomedich-167	111	51	l	l	NOUN
biomedich-167	111	52	/	/	SYM
biomedich-167	111	53	d	d	ADP
biomedich-167	111	54	4.91±0.09d	4.91±0.09d	NUM
biomedich-167	111	55	6.33±0.21d	6.33±0.21d	NUM
biomedich-167	111	56	50.25±4.21d	50.25±4.21d	NUM
biomedich-167	111	57	13.95±0.05d	13.95±0.05d	NUM
biomedich-167	111	58	data	datum	NOUN
biomedich-167	111	59	as	as	ADP
biomedich-167	111	60	mean	mean	PROPN
biomedich-167	111	61	±	±	NUM
biomedich-167	111	62	sem	sem	NOUN
biomedich-167	111	63	(	(	PUNCT
biomedich-167	111	64	standard	standard	ADJ
biomedich-167	111	65	error	error	NOUN
biomedich-167	111	66	of	of	ADP
biomedich-167	111	67	mean	mean	NOUN
biomedich-167	111	68	)	)	PUNCT
biomedich-167	111	69	n=	n=	ADJ
biomedich-167	111	70	5	5	NUM
biomedich-167	111	71	,	,	PUNCT
biomedich-167	111	72	nc	nc	ADJ
biomedich-167	111	73	:	:	PUNCT
biomedich-167	111	74	normal	normal	ADJ
biomedich-167	111	75	control	control	NOUN
biomedich-167	111	76	pu	pu	PROPN
biomedich-167	111	77	:	:	PUNCT
biomedich-167	111	78	negative	negative	ADJ
biomedich-167	111	79	control	control	PROPN
biomedich-167	111	80	cq	cq	NOUN
biomedich-167	111	81	:	:	PUNCT
biomedich-167	111	82	chloroquine	chloroquine	NOUN
biomedich-167	111	83	,	,	PUNCT
biomedich-167	111	84	d	d	NOUN
biomedich-167	111	85	:	:	PUNCT
biomedich-167	111	86	doxycycline	doxycycline	NOUN
biomedich-167	111	87	,	,	PUNCT
biomedich-167	111	88	a	a	PRON
biomedich-167	111	89	/	/	SYM
biomedich-167	111	90	l	l	NOUN
biomedich-167	111	91	:	:	PUNCT
biomedich-167	111	92	artemether	artemether	ADJ
biomedich-167	111	93	/	/	SYM
biomedich-167	111	94	lumefantrine	lumefantrine	ADJ
biomedich-167	111	95	,	,	PUNCT
biomedich-167	111	96	a	a	DET
biomedich-167	111	97	/	/	SYM
biomedich-167	111	98	l	l	NOUN
biomedich-167	111	99	/	/	SYM
biomedich-167	112	1	d	d	NOUN
biomedich-167	112	2	:	:	PUNCT
biomedich-167	112	3	artemether	artemether	ADJ
biomedich-167	112	4	/	/	SYM
biomedich-167	112	5	lumefantrine	lumefantrine	ADJ
biomedich-167	112	6	/	/	SYM
biomedich-167	112	7	doxycycline	doxycycline	NOUN
biomedich-167	112	8	,	,	PUNCT
biomedich-167	112	9	mst	mst	PROPN
biomedich-167	112	10	:	:	PUNCT
biomedich-167	112	11	mean	mean	VERB
biomedich-167	112	12	survival	survival	PROPN
biomedich-167	112	13	time	time	NOUN
biomedich-167	112	14	,	,	PUNCT
biomedich-167	112	15	rbcs	rbc	NOUN
biomedich-167	112	16	:	:	PUNCT
biomedich-167	112	17	red	red	ADJ
biomedich-167	112	18	blood	blood	NOUN
biomedich-167	112	19	count	count	NOUN
biomedich-167	112	20	,	,	PUNCT
biomedich-167	112	21	wbcs	wbc	NOUN
biomedich-167	112	22	:	:	PUNCT
biomedich-167	112	23	white	white	ADJ
biomedich-167	112	24	blood	blood	NOUN
biomedich-167	112	25	count	count	NOUN
biomedich-167	112	26	,	,	PUNCT
biomedich-167	112	27	pcv	pcv	NOUN
biomedich-167	112	28	:	:	PUNCT
biomedich-167	112	29	packed	pack	VERB
biomedich-167	112	30	cell	cell	NOUN
biomedich-167	112	31	volume	volume	NOUN
biomedich-167	112	32	hb	hb	PROPN
biomedich-167	112	33	:	:	PUNCT
biomedich-167	112	34	haemoglobin	haemoglobin	PROPN
biomedich-167	112	35	,	,	PUNCT
biomedich-167	112	36	a	a	DET
biomedich-167	112	37	p<0.001	p<0.001	ADJ
biomedich-167	112	38	significant	significant	ADJ
biomedich-167	112	39	difference	difference	NOUN
biomedich-167	112	40	when	when	SCONJ
biomedich-167	112	41	compared	compare	VERB
biomedich-167	112	42	to	to	ADP
biomedich-167	112	43	nc	nc	PROPN
biomedich-167	112	44	,	,	PUNCT
biomedich-167	112	45	b	b	PROPN
biomedich-167	112	46	p<0.01	p<0.01	PROPN
biomedich-167	112	47	,	,	PUNCT
biomedich-167	112	48	c	c	NOUN
biomedich-167	112	49	p<0.05	p<0.05	NOUN
biomedich-167	112	50	,	,	PUNCT
biomedich-167	112	51	d	d	NOUN
biomedich-167	112	52	p<0.001	p<0.001	X
biomedich-167	112	53	significant	significant	ADJ
biomedich-167	112	54	difference	difference	NOUN
biomedich-167	112	55	when	when	SCONJ
biomedich-167	112	56	compared	compare	VERB
biomedich-167	112	57	to	to	ADP
biomedich-167	112	58	pu	pu	PROPN
biomedich-167	112	59	.	.	PROPN
biomedich-167	112	60	table	table	NOUN
biomedich-167	112	61	5	5	NUM
biomedich-167	112	62	.	.	PUNCT
biomedich-167	112	63	effect	effect	NOUN
biomedich-167	112	64	of	of	ADP
biomedich-167	112	65	artemether	artemether	ADJ
biomedich-167	112	66	/	/	SYM
biomedich-167	112	67	lumefantrine	lumefantrine	ADJ
biomedich-167	112	68	/	/	SYM
biomedich-167	112	69	doxycycline	doxycycline	NOUN
biomedich-167	112	70	on	on	ADP
biomedich-167	112	71	lipid	lipid	ADJ
biomedich-167	112	72	parameters	parameter	NOUN
biomedich-167	112	73	of	of	ADP
biomedich-167	112	74	plasmodium	plasmodium	NOUN
biomedich-167	112	75	berghei	berghei	NOUN
biomedich-167	112	76	-	-	PUNCT
biomedich-167	112	77	infected	infect	VERB
biomedich-167	112	78	mice	mouse	NOUN
biomedich-167	112	79	.	.	PUNCT
biomedich-167	113	1	treatment	treatment	NOUN
biomedich-167	113	2	tg	tg	INTJ
biomedich-167	113	3	mg	mg	PROPN
biomedich-167	113	4	/	/	SYM
biomedich-167	113	5	dl	dl	PROPN
biomedich-167	113	6	chol	chol	PROPN
biomedich-167	113	7	mg	mg	PROPN
biomedich-167	113	8	/	/	SYM
biomedich-167	113	9	dl	dl	PROPN
biomedich-167	113	10	hdl	hdl	PROPN
biomedich-167	113	11	-	-	PUNCT
biomedich-167	113	12	c	c	PROPN
biomedich-167	113	13	mg	mg	PROPN
biomedich-167	113	14	/	/	SYM
biomedich-167	113	15	dl	dl	NOUN
biomedich-167	113	16	ldl	ldl	NOUN
biomedich-167	113	17	mg	mg	PROPN
biomedich-167	113	18	/	/	SYM
biomedich-167	113	19	dl	dl	PROPN
biomedich-167	113	20	nc	nc	PROPN
biomedich-167	113	21	76.8±8.03	76.8±8.03	NUM
biomedich-167	113	22	100.4±14.0	100.4±14.0	NUM
biomedich-167	113	23	55.9±5.66	55.9±5.66	NUM
biomedich-167	113	24	29.1±3.11	29.1±3.11	NUM
biomedich-167	113	25	pu	pu	PROPN
biomedich-167	113	26	266.3±15.0a	266.3±15.0a	PROPN
biomedich-167	113	27	298.4±14.1	298.4±14.1	NOUN
biomedich-167	113	28	a	a	DET
biomedich-167	113	29	24.6±2.32	24.6±2.32	NUM
biomedich-167	113	30	a	a	DET
biomedich-167	113	31	220.1±18.1a	220.1±18.1a	NUM
biomedich-167	113	32	cq	cq	NUM
biomedich-167	114	1	169.1±10.6	169.1±10.6	NUM
biomedich-167	114	2	b	b	PROPN
biomedich-167	114	3	190.8±16.4	190.8±16.4	NUM
biomedich-167	114	4	b	b	PROPN
biomedich-167	114	5	39.1±5.72	39.1±5.72	NUM
biomedich-167	114	6	b	b	NOUN
biomedich-167	114	7	117.8±11.6b	117.8±11.6b	NUM
biomedich-167	114	8	d	d	NOUN
biomedich-167	114	9	210.7±11.6	210.7±11.6	NOUN
biomedich-167	114	10	c	c	NOUN
biomedich-167	114	11	247.5±13.7	247.5±13.7	NUM
biomedich-167	114	12	c	c	NOUN
biomedich-167	114	13	30.0±3.19	30.0±3.19	NUM
biomedich-167	114	14	c	c	NOUN
biomedich-167	114	15	175.4±15.0c	175.4±15.0c	NUM
biomedich-167	114	16	a	a	PRON
biomedich-167	114	17	/	/	SYM
biomedich-167	114	18	l	l	NOUN
biomedich-167	114	19	179.0±14.0b	179.0±14.0b	PROPN
biomedich-167	114	20	199.6±14.3b	199.6±14.3b	NUM
biomedich-167	114	21	37.3±3.67b	37.3±3.67b	PROPN
biomedich-167	114	22	126.5±12.5b	126.5±12.5b	NUM
biomedich-167	114	23	a	a	DET
biomedich-167	114	24	/	/	SYM
biomedich-167	114	25	l	l	NOUN
biomedich-167	114	26	/	/	SYM
biomedich-167	115	1	d	d	NOUN
biomedich-167	115	2	80.9±7.49d	80.9±7.49d	NUM
biomedich-167	115	3	117.8±12.5	117.8±12.5	NUM
biomedich-167	115	4	d	d	NOUN
biomedich-167	115	5	49.5±4.39d	49.5±4.39d	NUM
biomedich-167	115	6	41.3±10.1d	41.3±10.1d	NUM
biomedich-167	115	7	data	datum	NOUN
biomedich-167	115	8	as	as	ADP
biomedich-167	115	9	mean	mean	PROPN
biomedich-167	115	10	±	±	NUM
biomedich-167	115	11	sem	sem	NOUN
biomedich-167	115	12	(	(	PUNCT
biomedich-167	115	13	standard	standard	ADJ
biomedich-167	115	14	error	error	NOUN
biomedich-167	115	15	of	of	ADP
biomedich-167	115	16	mean	mean	NOUN
biomedich-167	115	17	)	)	PUNCT
biomedich-167	115	18	n=	n=	ADJ
biomedich-167	115	19	5	5	NUM
biomedich-167	115	20	,	,	PUNCT
biomedich-167	115	21	nc	nc	ADJ
biomedich-167	115	22	:	:	PUNCT
biomedich-167	115	23	normal	normal	ADJ
biomedich-167	115	24	control	control	NOUN
biomedich-167	115	25	pu	pu	PROPN
biomedich-167	115	26	:	:	PUNCT
biomedich-167	115	27	negative	negative	ADJ
biomedich-167	115	28	control	control	PROPN
biomedich-167	115	29	cq	cq	NOUN
biomedich-167	115	30	:	:	PUNCT
biomedich-167	115	31	chloroquine	chloroquine	NOUN
biomedich-167	115	32	,	,	PUNCT
biomedich-167	115	33	d	d	NOUN
biomedich-167	115	34	:	:	PUNCT
biomedich-167	115	35	doxycycline	doxycycline	NOUN
biomedich-167	115	36	,	,	PUNCT
biomedich-167	115	37	a	a	PRON
biomedich-167	115	38	/	/	SYM
biomedich-167	115	39	l	l	NOUN
biomedich-167	115	40	:	:	PUNCT
biomedich-167	115	41	artemether	artemether	ADJ
biomedich-167	115	42	/	/	SYM
biomedich-167	115	43	lumefantrine	lumefantrine	ADJ
biomedich-167	115	44	,	,	PUNCT
biomedich-167	115	45	a	a	DET
biomedich-167	115	46	/	/	SYM
biomedich-167	115	47	l	l	NOUN
biomedich-167	115	48	/	/	SYM
biomedich-167	116	1	d	d	NOUN
biomedich-167	116	2	:	:	PUNCT
biomedich-167	116	3	artemether	artemether	ADJ
biomedich-167	116	4	/	/	SYM
biomedich-167	116	5	lumefantrine	lumefantrine	ADJ
biomedich-167	116	6	/	/	SYM
biomedich-167	116	7	doxycycline	doxycycline	NOUN
biomedich-167	116	8	,	,	PUNCT
biomedich-167	116	9	tg	tg	PROPN
biomedich-167	116	10	:	:	PUNCT
biomedich-167	116	11	tryglyceride	tryglyceride	ADV
biomedich-167	116	12	,	,	PUNCT
biomedich-167	116	13	chol	chol	PROPN
biomedich-167	116	14	:	:	PUNCT
biomedich-167	116	15	total	total	ADJ
biomedich-167	116	16	cholesterol	cholesterol	NOUN
biomedich-167	116	17	hdl	hdl	PROPN
biomedich-167	116	18	:	:	PUNCT
biomedich-167	116	19	high	high	ADJ
biomedich-167	116	20	density	density	NOUN
biomedich-167	116	21	lipoproteins	lipoprotein	NOUN
biomedich-167	116	22	,	,	PUNCT
biomedich-167	116	23	ldl	ldl	NOUN
biomedich-167	116	24	:	:	PUNCT
biomedich-167	116	25	low	low	ADJ
biomedich-167	116	26	density	density	NOUN
biomedich-167	116	27	lipoprotein	lipoprotein	ADJ
biomedich-167	116	28	,	,	PUNCT
biomedich-167	116	29	vldl	vldl	NOUN
biomedich-167	116	30	:	:	PUNCT
biomedich-167	116	31	very	very	ADV
biomedich-167	116	32	low	low	ADJ
biomedich-167	116	33	density	density	NOUN
biomedich-167	116	34	lipoprotein	lipoprotein	ADJ
biomedich-167	116	35	.	.	PUNCT
biomedich-167	117	1	a	a	DET
biomedich-167	117	2	p<0.001	p<0.001	X
biomedich-167	117	3	when	when	SCONJ
biomedich-167	117	4	compared	compare	VERB
biomedich-167	117	5	to	to	ADP
biomedich-167	117	6	nc	nc	PROPN
biomedich-167	117	7	,	,	PUNCT
biomedich-167	117	8	b	b	PROPN
biomedich-167	117	9	p<0.01	p<0.01	PROPN
biomedich-167	117	10	,	,	PUNCT
biomedich-167	117	11	c	c	NOUN
biomedich-167	117	12	p<0.05	p<0.05	NOUN
biomedich-167	117	13	,	,	PUNCT
biomedich-167	117	14	d	d	X
biomedich-167	117	15	p<0.001	p<0.001	X
biomedich-167	117	16	when	when	SCONJ
biomedich-167	117	17	compared	compare	VERB
biomedich-167	117	18	to	to	ADP
biomedich-167	117	19	pu	pu	PROPN
biomedich-167	117	20	.	.	PUNCT
biomedich-167	117	21	discussion	discussion	NOUN
biomedich-167	117	22	artemisinin	artemisinin	PROPN
biomedich-167	117	23	based	base	VERB
biomedich-167	117	24	combination	combination	NOUN
biomedich-167	117	25	therapies	therapy	NOUN
biomedich-167	117	26	(	(	PUNCT
biomedich-167	117	27	acts	act	NOUN
biomedich-167	117	28	)	)	PUNCT
biomedich-167	117	29	are	be	AUX
biomedich-167	117	30	used	use	VERB
biomedich-167	117	31	as	as	ADP
biomedich-167	117	32	treatment	treatment	NOUN
biomedich-167	117	33	for	for	ADP
biomedich-167	117	34	uncomplicated	uncomplicated	ADJ
biomedich-167	117	35	malaria	malaria	NOUN
biomedich-167	117	36	(	(	PUNCT
biomedich-167	117	37	who	who	PRON
biomedich-167	117	38	,	,	PUNCT
biomedich-167	117	39	2015	2015	NUM
biomedich-167	117	40	)	)	PUNCT
biomedich-167	117	41	.	.	PUNCT
biomedich-167	118	1	unfortunately	unfortunately	ADV
biomedich-167	118	2	,	,	PUNCT
biomedich-167	118	3	the	the	DET
biomedich-167	118	4	emergence	emergence	NOUN
biomedich-167	118	5	of	of	ADP
biomedich-167	118	6	plasmodium	plasmodium	NOUN
biomedich-167	118	7	parasite	parasite	NOUN
biomedich-167	118	8	resistant	resistant	ADJ
biomedich-167	118	9	to	to	ADP
biomedich-167	118	10	acts	act	NOUN
biomedich-167	118	11	has	have	AUX
biomedich-167	118	12	been	be	AUX
biomedich-167	118	13	reported	report	VERB
biomedich-167	118	14	in	in	ADP
biomedich-167	118	15	endemic	endemic	ADJ
biomedich-167	118	16	regions	region	NOUN
biomedich-167	118	17	(	(	PUNCT
biomedich-167	118	18	cui	cui	NOUN
biomedich-167	118	19	et	et	PROPN
biomedich-167	118	20	al	al	PROPN
biomedich-167	118	21	.	.	PROPN
biomedich-167	118	22	,	,	PUNCT
biomedich-167	118	23	2015	2015	NUM
biomedich-167	118	24	;	;	PUNCT
biomedich-167	118	25	who	who	PRON
biomedich-167	118	26	,	,	PUNCT
biomedich-167	118	27	2016	2016	NUM
biomedich-167	118	28	)	)	PUNCT
biomedich-167	118	29	.	.	PUNCT
biomedich-167	119	1	antimalarial	antimalarial	ADJ
biomedich-167	119	2	drug	drug	NOUN
biomedich-167	119	3	resistance	resistance	NOUN
biomedich-167	119	4	poses	pose	VERB
biomedich-167	119	5	one	one	NUM
biomedich-167	119	6	of	of	ADP
biomedich-167	119	7	the	the	DET
biomedich-167	119	8	greatest	great	ADJ
biomedich-167	119	9	threats	threat	NOUN
biomedich-167	119	10	to	to	ADP
biomedich-167	119	11	malaria	malaria	NOUN
biomedich-167	119	12	control	control	NOUN
biomedich-167	119	13	.	.	PUNCT
biomedich-167	120	1	in	in	ADP
biomedich-167	120	2	africa	africa	PROPN
biomedich-167	120	3	,	,	PUNCT
biomedich-167	120	4	the	the	DET
biomedich-167	120	5	efficacy	efficacy	NOUN
biomedich-167	120	6	of	of	ADP
biomedich-167	120	7	affordable	affordable	ADJ
biomedich-167	120	8	antimalarial	antimalarial	ADJ
biomedich-167	120	9	drugs	drug	NOUN
biomedich-167	120	10	is	be	AUX
biomedich-167	120	11	rapidly	rapidly	ADV
biomedich-167	120	12	declining	decline	VERB
biomedich-167	120	13	,	,	PUNCT
biomedich-167	120	14	and	and	CCONJ
biomedich-167	120	15	efficacious	efficacious	ADJ
biomedich-167	120	16	treatment	treatment	NOUN
biomedich-167	120	17	%	%	NOUN
biomedich-167	120	18	parasitemia	parasitemia	NOUN
biomedich-167	120	19	%	%	NOUN
biomedich-167	120	20	inhibition	inhibition	VERB
biomedich-167	120	21	mst	mst	PROPN
biomedich-167	120	22	(	(	PUNCT
biomedich-167	120	23	days	day	NOUN
biomedich-167	120	24	)	)	PUNCT
biomedich-167	121	1	pu	pu	PROPN
biomedich-167	121	2	38.10±4.95	38.10±4.95	NUM
biomedich-167	121	3	0.0	0.0	NUM
biomedich-167	121	4	9.02±0.11	9.02±0.11	NOUN
biomedich-167	121	5	cq	cq	NOUN
biomedich-167	121	6	9.14	9.14	NUM
biomedich-167	121	7	±0.20a	±0.20a	NOUN
biomedich-167	121	8	76.0	76.0	NUM
biomedich-167	121	9	25.30±2.37a	25.30±2.37a	NUM
biomedich-167	121	10	d	d	NOUN
biomedich-167	121	11	13.72±0.67b	13.72±0.67b	NUM
biomedich-167	121	12	60.4	60.4	NUM
biomedich-167	121	13	16.21±1.57b	16.21±1.57b	NUM
biomedich-167	121	14	a	a	PRON
biomedich-167	121	15	/	/	SYM
biomedich-167	121	16	l	l	NOUN
biomedich-167	121	17	11.30±0.13a	11.30±0.13a	NUM
biomedich-167	121	18	70.3	70.3	NUM
biomedich-167	121	19	24.82±3.48a	24.82±3.48a	NUM
biomedich-167	121	20	a	a	DET
biomedich-167	121	21	/	/	SYM
biomedich-167	121	22	l	l	NOUN
biomedich-167	121	23	/	/	SYM
biomedich-167	121	24	d	d	X
biomedich-167	121	25	3.43±0.08c	3.43±0.08c	NUM
biomedich-167	121	26	90.0	90.0	NUM
biomedich-167	121	27	31.63±3.21c	31.63±3.21c	NUM
biomedich-167	121	28	georgewill	georgewill	NOUN
biomedich-167	121	29	&	&	CCONJ
biomedich-167	121	30	adikwu	adikwu	PROPN
biomedich-167	121	31	–	–	PUNCT
biomedich-167	121	32	potential	potential	ADJ
biomedich-167	121	33	antimalarial	antimalarial	ADJ
biomedich-167	121	34	activity	activity	NOUN
biomedich-167	121	35	of	of	ADP
biomedich-167	121	36	artemether	artemether	ADJ
biomedich-167	121	37	/	/	SYM
biomedich-167	121	38	lumefantrine	lumefantrine	ADJ
biomedich-167	121	39	/	/	SYM
biomedich-167	121	40	doxycycline	doxycycline	NOUN
biomedich-167	121	41	:	:	PUNCT
biomedich-167	121	42	…	…	PUNCT
biomedich-167	121	43	5	5	NUM
biomedich-167	121	44	antimalarial	antimalarial	ADJ
biomedich-167	121	45	drugs	drug	NOUN
biomedich-167	121	46	tend	tend	VERB
biomedich-167	121	47	to	to	PART
biomedich-167	121	48	be	be	AUX
biomedich-167	121	49	too	too	ADV
biomedich-167	121	50	expensive	expensive	ADJ
biomedich-167	121	51	.	.	PUNCT
biomedich-167	122	1	costeffective	costeffective	ADJ
biomedich-167	122	2	methods	method	NOUN
biomedich-167	122	3	are	be	AUX
biomedich-167	122	4	needed	need	VERB
biomedich-167	122	5	to	to	PART
biomedich-167	122	6	fight	fight	VERB
biomedich-167	122	7	against	against	ADP
biomedich-167	122	8	antimalarial	antimalarial	ADJ
biomedich-167	122	9	drug	drug	NOUN
biomedich-167	122	10	resistance	resistance	NOUN
biomedich-167	122	11	.	.	PUNCT
biomedich-167	123	1	one	one	NUM
biomedich-167	123	2	of	of	ADP
biomedich-167	123	3	the	the	DET
biomedich-167	123	4	primary	primary	ADJ
biomedich-167	123	5	solutions	solution	NOUN
biomedich-167	123	6	to	to	ADP
biomedich-167	123	7	challenges	challenge	NOUN
biomedich-167	123	8	associated	associate	VERB
biomedich-167	123	9	with	with	ADP
biomedich-167	123	10	plasmodium	plasmodium	NOUN
biomedich-167	123	11	parasites	parasite	NOUN
biomedich-167	123	12	resistance	resistance	NOUN
biomedich-167	123	13	to	to	ADP
biomedich-167	123	14	antimalarial	antimalarial	ADJ
biomedich-167	123	15	drugs	drug	NOUN
biomedich-167	123	16	is	be	AUX
biomedich-167	123	17	to	to	PART
biomedich-167	123	18	explore	explore	VERB
biomedich-167	123	19	new	new	ADJ
biomedich-167	123	20	combination	combination	NOUN
biomedich-167	123	21	therapies	therapy	NOUN
biomedich-167	123	22	.	.	PUNCT
biomedich-167	124	1	in	in	ADP
biomedich-167	124	2	combination	combination	NOUN
biomedich-167	124	3	therapy	therapy	NOUN
biomedich-167	124	4	,	,	PUNCT
biomedich-167	124	5	the	the	DET
biomedich-167	124	6	possibility	possibility	NOUN
biomedich-167	124	7	of	of	ADP
biomedich-167	124	8	the	the	DET
biomedich-167	124	9	plasmodium	plasmodium	NOUN
biomedich-167	124	10	parasites	parasite	NOUN
biomedich-167	124	11	developing	develop	VERB
biomedich-167	124	12	resistance	resistance	NOUN
biomedich-167	124	13	simultaneously	simultaneously	ADV
biomedich-167	124	14	to	to	ADP
biomedich-167	124	15	two	two	NUM
biomedich-167	124	16	or	or	CCONJ
biomedich-167	124	17	more	more	ADV
biomedich-167	124	18	combined	combine	VERB
biomedich-167	124	19	drugs	drug	NOUN
biomedich-167	124	20	with	with	ADP
biomedich-167	124	21	different	different	ADJ
biomedich-167	124	22	mechanisms	mechanism	NOUN
biomedich-167	124	23	of	of	ADP
biomedich-167	124	24	action	action	NOUN
biomedich-167	124	25	is	be	AUX
biomedich-167	124	26	extremely	extremely	ADV
biomedich-167	124	27	low	low	ADJ
biomedich-167	124	28	(	(	PUNCT
biomedich-167	124	29	who	who	PRON
biomedich-167	124	30	,	,	PUNCT
biomedich-167	124	31	2001	2001	NUM
biomedich-167	124	32	)	)	PUNCT
biomedich-167	124	33	.	.	PUNCT
biomedich-167	125	1	the	the	DET
biomedich-167	125	2	current	current	ADJ
biomedich-167	125	3	study	study	NOUN
biomedich-167	125	4	examined	examine	VERB
biomedich-167	125	5	the	the	DET
biomedich-167	125	6	antiplasmodial	antiplasmodial	ADJ
biomedich-167	125	7	activity	activity	NOUN
biomedich-167	125	8	of	of	ADP
biomedich-167	125	9	a	a	DET
biomedich-167	125	10	/	/	SYM
biomedich-167	125	11	l	l	NOUN
biomedich-167	125	12	/	/	SYM
biomedich-167	125	13	d	d	NOUN
biomedich-167	125	14	on	on	ADP
biomedich-167	125	15	p.	p.	PROPN
biomedich-167	125	16	berghei	berghei	PROPN
biomedich-167	125	17	-	-	PUNCT
biomedich-167	125	18	infected	infect	VERB
biomedich-167	125	19	mice	mouse	NOUN
biomedich-167	125	20	.	.	PUNCT
biomedich-167	126	1	p.	p.	NOUN
biomedich-167	126	2	berghei	berghei	PROPN
biomedich-167	126	3	is	be	AUX
biomedich-167	126	4	used	use	VERB
biomedich-167	126	5	in	in	ADP
biomedich-167	126	6	predicting	predict	VERB
biomedich-167	126	7	treatment	treatment	NOUN
biomedich-167	126	8	outcomes	outcome	NOUN
biomedich-167	126	9	of	of	ADP
biomedich-167	126	10	antimalarial	antimalarial	ADJ
biomedich-167	126	11	drug	drug	NOUN
biomedich-167	126	12	candidates	candidate	NOUN
biomedich-167	126	13	,	,	PUNCT
biomedich-167	126	14	due	due	ADP
biomedich-167	126	15	to	to	ADP
biomedich-167	126	16	its	its	PRON
biomedich-167	126	17	sensitivity	sensitivity	NOUN
biomedich-167	126	18	,	,	PUNCT
biomedich-167	126	19	making	make	VERB
biomedich-167	126	20	it	it	PRON
biomedich-167	126	21	an	an	DET
biomedich-167	126	22	important	important	ADJ
biomedich-167	126	23	parasite	parasite	NOUN
biomedich-167	126	24	for	for	ADP
biomedich-167	126	25	antiplasmodial	antiplasmodial	ADJ
biomedich-167	126	26	studies	study	NOUN
biomedich-167	126	27	(	(	PUNCT
biomedich-167	126	28	unekwuojo	unekwuojo	NOUN
biomedich-167	126	29	et	et	PROPN
biomedich-167	126	30	al	al	PROPN
biomedich-167	126	31	.	.	PROPN
biomedich-167	126	32	,	,	PUNCT
biomedich-167	126	33	2011	2011	NUM
biomedich-167	126	34	)	)	PUNCT
biomedich-167	126	35	.	.	PUNCT
biomedich-167	127	1	studies	study	NOUN
biomedich-167	127	2	have	have	AUX
biomedich-167	127	3	shown	show	VERB
biomedich-167	127	4	that	that	SCONJ
biomedich-167	127	5	suppressive	suppressive	NOUN
biomedich-167	127	6	and	and	CCONJ
biomedich-167	127	7	curative	curative	ADJ
biomedich-167	127	8	tests	test	NOUN
biomedich-167	127	9	are	be	AUX
biomedich-167	127	10	effective	effective	ADJ
biomedich-167	127	11	in	in	ADP
biomedich-167	127	12	the	the	DET
biomedich-167	127	13	antiplasmodial	antiplasmodial	ADJ
biomedich-167	127	14	evaluation	evaluation	NOUN
biomedich-167	127	15	of	of	ADP
biomedich-167	127	16	candidate	candidate	NOUN
biomedich-167	127	17	drugs	drug	NOUN
biomedich-167	127	18	on	on	ADP
biomedich-167	127	19	early	early	ADJ
biomedich-167	127	20	and	and	CCONJ
biomedich-167	127	21	established	establish	VERB
biomedich-167	127	22	infections	infection	NOUN
biomedich-167	127	23	,	,	PUNCT
biomedich-167	127	24	respectively	respectively	ADV
biomedich-167	127	25	.	.	PUNCT
biomedich-167	128	1	importantly	importantly	ADV
biomedich-167	128	2	,	,	PUNCT
biomedich-167	128	3	suppressive	suppressive	ADJ
biomedich-167	128	4	and	and	CCONJ
biomedich-167	128	5	curative	curative	ADJ
biomedich-167	128	6	tests	test	NOUN
biomedich-167	128	7	give	give	VERB
biomedich-167	128	8	vital	vital	ADJ
biomedich-167	128	9	information	information	NOUN
biomedich-167	128	10	on	on	ADP
biomedich-167	128	11	percentage	percentage	NOUN
biomedich-167	128	12	parasitemia	parasitemia	NOUN
biomedich-167	128	13	,	,	PUNCT
biomedich-167	128	14	and	and	CCONJ
biomedich-167	128	15	parasitemia	parasitemia	NOUN
biomedich-167	128	16	inhibitions	inhibition	NOUN
biomedich-167	128	17	(	(	PUNCT
biomedich-167	128	18	bobasa	bobasa	PROPN
biomedich-167	128	19	et	et	PROPN
biomedich-167	128	20	al	al	PROPN
biomedich-167	128	21	.	.	PROPN
biomedich-167	128	22	,	,	PUNCT
biomedich-167	128	23	2018	2018	NUM
biomedich-167	128	24	)	)	PUNCT
biomedich-167	128	25	.	.	PUNCT
biomedich-167	129	1	in	in	ADP
biomedich-167	129	2	the	the	DET
biomedich-167	129	3	current	current	ADJ
biomedich-167	129	4	study	study	NOUN
biomedich-167	129	5	,	,	PUNCT
biomedich-167	129	6	treatment	treatment	NOUN
biomedich-167	129	7	with	with	ADP
biomedich-167	129	8	a	a	DET
biomedich-167	129	9	/	/	SYM
biomedich-167	129	10	l	l	NOUN
biomedich-167	129	11	/	/	SYM
biomedich-167	129	12	d	d	NOUN
biomedich-167	129	13	produced	produce	VERB
biomedich-167	129	14	the	the	DET
biomedich-167	129	15	best	well	ADV
biomedich-167	129	16	curative	curative	ADJ
biomedich-167	129	17	and	and	CCONJ
biomedich-167	129	18	suppressive	suppressive	ADJ
biomedich-167	129	19	antiplasmodial	antiplasmodial	ADJ
biomedich-167	129	20	effects	effect	NOUN
biomedich-167	129	21	in	in	ADP
biomedich-167	129	22	relation	relation	NOUN
biomedich-167	129	23	to	to	ADP
biomedich-167	129	24	individual	individual	ADJ
biomedich-167	129	25	doses	dose	NOUN
biomedich-167	129	26	of	of	ADP
biomedich-167	129	27	a	a	DET
biomedich-167	129	28	/	/	SYM
biomedich-167	129	29	l	l	NOUN
biomedich-167	129	30	,	,	PUNCT
biomedich-167	129	31	d	d	PROPN
biomedich-167	129	32	and	and	CCONJ
biomedich-167	129	33	cq	cq	NOUN
biomedich-167	129	34	.	.	PROPN
biomedich-167	130	1	in	in	ADP
biomedich-167	130	2	the	the	DET
biomedich-167	130	3	curative	curative	ADJ
biomedich-167	130	4	study	study	NOUN
biomedich-167	130	5	,	,	PUNCT
biomedich-167	130	6	treatment	treatment	NOUN
biomedich-167	130	7	with	with	ADP
biomedich-167	130	8	d	d	PROPN
biomedich-167	130	9	,	,	PUNCT
biomedich-167	130	10	a	a	DET
biomedich-167	130	11	/	/	SYM
biomedich-167	130	12	l	l	NOUN
biomedich-167	130	13	,	,	PUNCT
biomedich-167	130	14	and	and	CCONJ
biomedich-167	130	15	a	a	DET
biomedich-167	130	16	/	/	SYM
biomedich-167	130	17	l	l	NOUN
biomedich-167	130	18	/	/	SYM
biomedich-167	130	19	d	d	NOUN
biomedich-167	130	20	produced	produce	VERB
biomedich-167	130	21	60.4	60.4	NUM
biomedich-167	130	22	%	%	NOUN
biomedich-167	130	23	,	,	PUNCT
biomedich-167	130	24	70.3	70.3	NUM
biomedich-167	130	25	%	%	NOUN
biomedich-167	130	26	,	,	PUNCT
biomedich-167	130	27	and	and	CCONJ
biomedich-167	130	28	90.0	90.0	NUM
biomedich-167	130	29	%	%	NOUN
biomedich-167	130	30	inhibitions	inhibition	NOUN
biomedich-167	130	31	,	,	PUNCT
biomedich-167	130	32	respectively	respectively	ADV
biomedich-167	130	33	.	.	PUNCT
biomedich-167	131	1	in	in	ADP
biomedich-167	131	2	the	the	DET
biomedich-167	131	3	suppressive	suppressive	ADJ
biomedich-167	131	4	study	study	NOUN
biomedich-167	131	5	,	,	PUNCT
biomedich-167	131	6	treatment	treatment	NOUN
biomedich-167	131	7	with	with	ADP
biomedich-167	131	8	d	d	PROPN
biomedich-167	131	9	,	,	PUNCT
biomedich-167	131	10	a	a	DET
biomedich-167	131	11	/	/	SYM
biomedich-167	131	12	l	l	NOUN
biomedich-167	131	13	and	and	CCONJ
biomedich-167	131	14	a	a	DET
biomedich-167	131	15	/	/	SYM
biomedich-167	131	16	l	l	NOUN
biomedich-167	131	17	/	/	SYM
biomedich-167	131	18	d	d	NOUN
biomedich-167	131	19	produced	produce	VERB
biomedich-167	131	20	63.2	63.2	NUM
biomedich-167	131	21	%	%	NOUN
biomedich-167	131	22	,	,	PUNCT
biomedich-167	131	23	80.1	80.1	NUM
biomedich-167	131	24	%	%	NOUN
biomedich-167	131	25	and	and	CCONJ
biomedich-167	131	26	92	92	NUM
biomedich-167	131	27	.	.	PUNCT
biomedich-167	132	1	3	3	NUM
biomedich-167	132	2	%	%	NOUN
biomedich-167	132	3	inhibitions	inhibition	NOUN
biomedich-167	132	4	,	,	PUNCT
biomedich-167	132	5	respectively	respectively	ADV
biomedich-167	132	6	.	.	PUNCT
biomedich-167	133	1	the	the	DET
biomedich-167	133	2	prophylactic	prophylactic	ADJ
biomedich-167	133	3	study	study	NOUN
biomedich-167	133	4	showed	show	VERB
biomedich-167	133	5	best	good	ADJ
biomedich-167	133	6	decrease	decrease	NOUN
biomedich-167	133	7	in	in	ADP
biomedich-167	133	8	parasitemia	parasitemia	NOUN
biomedich-167	133	9	level	level	NOUN
biomedich-167	133	10	in	in	ADP
biomedich-167	133	11	a	a	DET
biomedich-167	133	12	/	/	SYM
biomedich-167	133	13	l	l	NOUN
biomedich-167	133	14	/	/	SYM
biomedich-167	133	15	d	d	VERB
biomedich-167	133	16	-	-	PUNCT
biomedich-167	133	17	treated	treat	VERB
biomedich-167	133	18	mice	mouse	NOUN
biomedich-167	133	19	when	when	SCONJ
biomedich-167	133	20	compared	compare	VERB
biomedich-167	133	21	to	to	ADP
biomedich-167	133	22	individual	individual	ADJ
biomedich-167	133	23	doses	dose	NOUN
biomedich-167	133	24	of	of	ADP
biomedich-167	133	25	a	a	DET
biomedich-167	133	26	/	/	SYM
biomedich-167	133	27	l	l	NOUN
biomedich-167	133	28	,	,	PUNCT
biomedich-167	133	29	d	d	PROPN
biomedich-167	133	30	and	and	CCONJ
biomedich-167	133	31	cq	cq	NOUN
biomedich-167	133	32	.	.	PUNCT
biomedich-167	134	1	the	the	DET
biomedich-167	134	2	observed	observed	ADJ
biomedich-167	134	3	parasitemia	parasitemia	NOUN
biomedich-167	134	4	inhibitions	inhibition	VERB
biomedich-167	134	5	in	in	ADP
biomedich-167	134	6	the	the	DET
biomedich-167	134	7	prophylactic	prophylactic	ADJ
biomedich-167	134	8	study	study	NOUN
biomedich-167	134	9	were	be	AUX
biomedich-167	134	10	65.1	65.1	NUM
biomedich-167	134	11	%	%	NOUN
biomedich-167	134	12	,	,	PUNCT
biomedich-167	134	13	82.8	82.8	NUM
biomedich-167	134	14	%	%	NOUN
biomedich-167	134	15	,	,	PUNCT
biomedich-167	134	16	and	and	CCONJ
biomedich-167	134	17	93.9	93.9	NUM
biomedich-167	134	18	%	%	NOUN
biomedich-167	134	19	,	,	PUNCT
biomedich-167	134	20	and	and	CCONJ
biomedich-167	134	21	86.7	86.7	NUM
biomedich-167	134	22	%	%	NOUN
biomedich-167	134	23	in	in	ADP
biomedich-167	134	24	mice	mouse	NOUN
biomedich-167	134	25	treated	treat	VERB
biomedich-167	134	26	with	with	ADP
biomedich-167	134	27	d	d	PROPN
biomedich-167	134	28	,	,	PUNCT
biomedich-167	134	29	a	a	DET
biomedich-167	134	30	/	/	SYM
biomedich-167	134	31	l	l	NOUN
biomedich-167	134	32	,	,	PUNCT
biomedich-167	134	33	a	a	DET
biomedich-167	134	34	/	/	SYM
biomedich-167	134	35	l	l	NOUN
biomedich-167	134	36	/	/	SYM
biomedich-167	134	37	d	d	PROPN
biomedich-167	134	38	and	and	CCONJ
biomedich-167	134	39	cq	cq	NOUN
biomedich-167	134	40	,	,	PUNCT
biomedich-167	134	41	respectively	respectively	ADV
biomedich-167	134	42	.	.	PUNCT
biomedich-167	135	1	in	in	ADP
biomedich-167	135	2	addition	addition	NOUN
biomedich-167	135	3	to	to	ADP
biomedich-167	135	4	percentage	percentage	NOUN
biomedich-167	135	5	parasitemia	parasitemia	NOUN
biomedich-167	135	6	and	and	CCONJ
biomedich-167	135	7	inhibition	inhibition	NOUN
biomedich-167	135	8	,	,	PUNCT
biomedich-167	135	9	this	this	DET
biomedich-167	135	10	study	study	NOUN
biomedich-167	135	11	determined	determine	VERB
biomedich-167	135	12	the	the	DET
biomedich-167	135	13	mst	mst	PROPN
biomedich-167	135	14	of	of	ADP
biomedich-167	135	15	the	the	DET
biomedich-167	135	16	mice	mouse	NOUN
biomedich-167	135	17	used	use	VERB
biomedich-167	135	18	for	for	ADP
biomedich-167	135	19	the	the	DET
biomedich-167	135	20	curative	curative	ADJ
biomedich-167	135	21	,	,	PUNCT
biomedich-167	135	22	suppressive	suppressive	ADJ
biomedich-167	135	23	and	and	CCONJ
biomedich-167	135	24	prophylactic	prophylactic	ADJ
biomedich-167	135	25	tests	test	NOUN
biomedich-167	135	26	(	(	PUNCT
biomedich-167	135	27	georgewill	georgewill	NOUN
biomedich-167	135	28	et	et	PROPN
biomedich-167	135	29	al	al	PROPN
biomedich-167	135	30	.	.	PROPN
biomedich-167	135	31	,	,	PUNCT
biomedich-167	135	32	2021	2021	NUM
biomedich-167	135	33	)	)	PUNCT
biomedich-167	135	34	to	to	PART
biomedich-167	135	35	further	far	ADV
biomedich-167	135	36	buttress	buttress	VERB
biomedich-167	135	37	the	the	DET
biomedich-167	135	38	antiplasmodial	antiplasmodial	ADJ
biomedich-167	135	39	activity	activity	NOUN
biomedich-167	135	40	of	of	ADP
biomedich-167	135	41	a	a	DET
biomedich-167	135	42	/	/	SYM
biomedich-167	135	43	l	l	NOUN
biomedich-167	135	44	/	/	SYM
biomedich-167	135	45	d.	d.	PROPN
biomedich-167	135	46	studies	study	NOUN
biomedich-167	135	47	have	have	AUX
biomedich-167	135	48	shown	show	VERB
biomedich-167	135	49	that	that	DET
biomedich-167	135	50	candidate	candidate	NOUN
biomedich-167	135	51	drugs	drug	NOUN
biomedich-167	135	52	that	that	PRON
biomedich-167	135	53	can	can	AUX
biomedich-167	135	54	appreciably	appreciably	ADV
biomedich-167	135	55	prolong	prolong	VERB
biomedich-167	135	56	the	the	DET
biomedich-167	135	57	mst	mst	PROPN
biomedich-167	135	58	of	of	ADP
biomedich-167	135	59	parasitized	parasitize	VERB
biomedich-167	135	60	animals	animal	NOUN
biomedich-167	135	61	may	may	AUX
biomedich-167	135	62	be	be	AUX
biomedich-167	135	63	active	active	ADJ
biomedich-167	135	64	against	against	ADP
biomedich-167	135	65	malaria	malaria	NOUN
biomedich-167	135	66	(	(	PUNCT
biomedich-167	135	67	oliveira	oliveira	PROPN
biomedich-167	135	68	et	et	PROPN
biomedich-167	135	69	al	al	PROPN
biomedich-167	135	70	.	.	PROPN
biomedich-167	135	71	,	,	PUNCT
biomedich-167	135	72	2009	2009	NUM
biomedich-167	135	73	)	)	PUNCT
biomedich-167	135	74	.	.	PUNCT
biomedich-167	136	1	in	in	ADP
biomedich-167	136	2	the	the	DET
biomedich-167	136	3	current	current	ADJ
biomedich-167	136	4	study	study	NOUN
biomedich-167	136	5	,	,	PUNCT
biomedich-167	136	6	curative	curative	ADJ
biomedich-167	136	7	,	,	PUNCT
biomedich-167	136	8	suppressive	suppressive	ADJ
biomedich-167	136	9	and	and	CCONJ
biomedich-167	136	10	prophylactic	prophylactic	ADJ
biomedich-167	136	11	tests	test	NOUN
biomedich-167	136	12	showed	show	VERB
biomedich-167	136	13	best	good	ADJ
biomedich-167	136	14	prolongation	prolongation	NOUN
biomedich-167	136	15	of	of	ADP
biomedich-167	136	16	mst	mst	PROPN
biomedich-167	136	17	in	in	ADP
biomedich-167	136	18	mice	mouse	NOUN
biomedich-167	136	19	treated	treat	VERB
biomedich-167	136	20	with	with	ADP
biomedich-167	136	21	a	a	DET
biomedich-167	136	22	/	/	SYM
biomedich-167	136	23	l	l	NOUN
biomedich-167	136	24	/	/	SYM
biomedich-167	136	25	d	d	NOUN
biomedich-167	136	26	than	than	ADP
biomedich-167	136	27	d	d	PROPN
biomedich-167	136	28	,	,	PUNCT
biomedich-167	136	29	a	a	DET
biomedich-167	136	30	/	/	SYM
biomedich-167	136	31	l	l	NOUN
biomedich-167	136	32	,	,	PUNCT
biomedich-167	136	33	and	and	CCONJ
biomedich-167	136	34	cq	cq	NOUN
biomedich-167	136	35	alone	alone	ADV
biomedich-167	136	36	.	.	PUNCT
biomedich-167	137	1	in	in	ADP
biomedich-167	137	2	the	the	DET
biomedich-167	137	3	curative	curative	ADJ
biomedich-167	137	4	study	study	NOUN
biomedich-167	137	5	,	,	PUNCT
biomedich-167	137	6	d	d	X
biomedich-167	137	7	,	,	PUNCT
biomedich-167	137	8	a	a	DET
biomedich-167	137	9	/	/	SYM
biomedich-167	137	10	l	l	NOUN
biomedich-167	137	11	and	and	CCONJ
biomedich-167	137	12	a	a	DET
biomedich-167	137	13	/	/	SYM
biomedich-167	137	14	l	l	NOUN
biomedich-167	137	15	/	/	SYM
biomedich-167	137	16	d	d	PROPN
biomedich-167	137	17	prolonged	prolong	VERB
biomedich-167	137	18	mst	mst	PROPN
biomedich-167	137	19	to	to	ADP
biomedich-167	137	20	16.21±1.57	16.21±1.57	NUM
biomedich-167	137	21	,	,	PUNCT
biomedich-167	137	22	24.82±3.48	24.82±3.48	NUM
biomedich-167	137	23	and	and	CCONJ
biomedich-167	137	24	31.63±3.21	31.63±3.21	NUM
biomedich-167	137	25	days	day	NOUN
biomedich-167	137	26	,	,	PUNCT
biomedich-167	137	27	respectively	respectively	ADV
biomedich-167	137	28	.	.	PUNCT
biomedich-167	138	1	studies	study	NOUN
biomedich-167	138	2	have	have	AUX
biomedich-167	138	3	shown	show	VERB
biomedich-167	138	4	that	that	PRON
biomedich-167	138	5	plasmodium	plasmodium	NOUN
biomedich-167	138	6	depend	depend	VERB
biomedich-167	138	7	on	on	ADP
biomedich-167	138	8	host	host	NOUN
biomedich-167	138	9	hemoglobin	hemoglobin	NOUN
biomedich-167	138	10	as	as	ADP
biomedich-167	138	11	a	a	DET
biomedich-167	138	12	nutrientsource	nutrientsource	NOUN
biomedich-167	138	13	for	for	ADP
biomedich-167	138	14	growth	growth	NOUN
biomedich-167	138	15	and	and	CCONJ
biomedich-167	138	16	multiplication	multiplication	NOUN
biomedich-167	138	17	.	.	PUNCT
biomedich-167	139	1	it	it	PRON
biomedich-167	139	2	consumes	consume	VERB
biomedich-167	139	3	more	more	ADJ
biomedich-167	139	4	than	than	ADP
biomedich-167	139	5	75	75	NUM
biomedich-167	139	6	%	%	NOUN
biomedich-167	139	7	of	of	ADP
biomedich-167	139	8	haemoglobin	haemoglobin	NOUN
biomedich-167	139	9	during	during	ADP
biomedich-167	139	10	its	its	PRON
biomedich-167	139	11	intra	intra	ADJ
biomedich-167	139	12	-	-	ADJ
biomedich-167	139	13	erythrocytic	erythrocytic	ADJ
biomedich-167	139	14	phase	phase	NOUN
biomedich-167	139	15	and	and	CCONJ
biomedich-167	139	16	metabolizes	metabolize	NOUN
biomedich-167	139	17	heme	heme	NOUN
biomedich-167	139	18	into	into	ADP
biomedich-167	139	19	hemozoin	hemozoin	NOUN
biomedich-167	139	20	(	(	PUNCT
biomedich-167	139	21	inbaneson	inbaneson	NOUN
biomedich-167	139	22	and	and	CCONJ
biomedich-167	139	23	sundaram	sundaram	PROPN
biomedich-167	139	24	2012	2012	NUM
biomedich-167	139	25	)	)	PUNCT
biomedich-167	139	26	.	.	PUNCT
biomedich-167	140	1	p.	p.	NOUN
biomedich-167	140	2	berghei	berghei	PROPN
biomedich-167	140	3	-	-	PUNCT
biomedich-167	140	4	infected	infect	VERB
biomedich-167	140	5	mice	mouse	NOUN
biomedich-167	140	6	are	be	AUX
biomedich-167	140	7	prone	prone	ADJ
biomedich-167	140	8	to	to	ADP
biomedich-167	140	9	anemia	anemia	NOUN
biomedich-167	140	10	due	due	ADP
biomedich-167	140	11	to	to	ADP
biomedich-167	140	12	erythrocyte	erythrocyte	NOUN
biomedich-167	140	13	destruction	destruction	NOUN
biomedich-167	140	14	,	,	PUNCT
biomedich-167	140	15	as	as	ADP
biomedich-167	140	16	a	a	DET
biomedich-167	140	17	consequence	consequence	NOUN
biomedich-167	140	18	of	of	ADP
biomedich-167	140	19	parasite	parasite	ADJ
biomedich-167	140	20	multiplication	multiplication	NOUN
biomedich-167	140	21	or	or	CCONJ
biomedich-167	140	22	by	by	ADP
biomedich-167	140	23	spleen	spleen	ADJ
biomedich-167	140	24	reticuloendotelial	reticuloendotelial	ADJ
biomedich-167	140	25	cell	cell	NOUN
biomedich-167	140	26	action	action	NOUN
biomedich-167	140	27	causing	cause	VERB
biomedich-167	140	28	the	the	DET
biomedich-167	140	29	production	production	NOUN
biomedich-167	140	30	of	of	ADP
biomedich-167	140	31	phagocytes	phagocyte	NOUN
biomedich-167	140	32	by	by	ADP
biomedich-167	140	33	the	the	DET
biomedich-167	140	34	spleen	spleen	NOUN
biomedich-167	140	35	due	due	ADP
biomedich-167	140	36	to	to	ADP
biomedich-167	140	37	abnormal	abnormal	ADJ
biomedich-167	140	38	erythrocytes	erythrocyte	NOUN
biomedich-167	140	39	(	(	PUNCT
biomedich-167	140	40	nardos	nardo	NOUN
biomedich-167	140	41	and	and	CCONJ
biomedich-167	140	42	makonnen	makonnen	NOUN
biomedich-167	140	43	,	,	PUNCT
biomedich-167	140	44	2017	2017	NUM
biomedich-167	140	45	)	)	PUNCT
biomedich-167	140	46	.	.	PUNCT
biomedich-167	141	1	in	in	ADP
biomedich-167	141	2	the	the	DET
biomedich-167	141	3	current	current	ADJ
biomedich-167	141	4	study	study	NOUN
biomedich-167	141	5	,	,	PUNCT
biomedich-167	141	6	anemia	anemia	NOUN
biomedich-167	141	7	was	be	AUX
biomedich-167	141	8	conspicuous	conspicuous	ADJ
biomedich-167	141	9	in	in	ADP
biomedich-167	141	10	p.	p.	PROPN
biomedich-167	141	11	berghei	berghei	PROPN
biomedich-167	141	12	-	-	PUNCT
biomedich-167	141	13	infected	infect	VERB
biomedich-167	141	14	mice	mouse	NOUN
biomedich-167	141	15	characterized	characterize	VERB
biomedich-167	141	16	by	by	ADP
biomedich-167	141	17	decreased	decrease	VERB
biomedich-167	141	18	pcv	pcv	PROPN
biomedich-167	141	19	,	,	PUNCT
biomedich-167	141	20	hb	hb	PROPN
biomedich-167	141	21	,	,	PUNCT
biomedich-167	141	22	and	and	CCONJ
biomedich-167	141	23	rbcs	rbc	NOUN
biomedich-167	141	24	with	with	ADP
biomedich-167	141	25	increased	increase	VERB
biomedich-167	141	26	wbcs	wbc	NOUN
biomedich-167	141	27	levels	level	NOUN
biomedich-167	141	28	.	.	PUNCT
biomedich-167	142	1	however	however	ADV
biomedich-167	142	2	,	,	PUNCT
biomedich-167	142	3	p.	p.	PROPN
biomedich-167	142	4	berghei	berghei	PROPN
biomedich-167	142	5	–	–	PUNCT
biomedich-167	142	6	induced	induced	ADJ
biomedich-167	142	7	anemia	anemia	NOUN
biomedich-167	142	8	was	be	AUX
biomedich-167	142	9	vividly	vividly	ADV
biomedich-167	142	10	reduced	reduce	VERB
biomedich-167	142	11	in	in	ADP
biomedich-167	142	12	mice	mouse	NOUN
biomedich-167	142	13	treated	treat	VERB
biomedich-167	142	14	with	with	ADP
biomedich-167	142	15	a	a	DET
biomedich-167	142	16	/	/	SYM
biomedich-167	142	17	l	l	NOUN
biomedich-167	142	18	/	/	SYM
biomedich-167	142	19	d	d	NOUN
biomedich-167	142	20	which	which	PRON
biomedich-167	142	21	was	be	AUX
biomedich-167	142	22	characterized	characterize	VERB
biomedich-167	142	23	by	by	ADP
biomedich-167	142	24	increased	increase	VERB
biomedich-167	142	25	pcv	pcv	NOUN
biomedich-167	142	26	,	,	PUNCT
biomedich-167	142	27	hb	hb	PROPN
biomedich-167	142	28	,	,	PUNCT
biomedich-167	142	29	and	and	CCONJ
biomedich-167	142	30	rbcs	rbc	NOUN
biomedich-167	142	31	levels	level	NOUN
biomedich-167	142	32	and	and	CCONJ
biomedich-167	142	33	decreased	decrease	VERB
biomedich-167	142	34	wbcs	wbc	NOUN
biomedich-167	142	35	levels	level	NOUN
biomedich-167	142	36	.	.	PUNCT
biomedich-167	143	1	interestingly	interestingly	ADV
biomedich-167	143	2	,	,	PUNCT
biomedich-167	143	3	the	the	DET
biomedich-167	143	4	anti	anti	ADJ
biomedich-167	143	5	-	-	ADJ
biomedich-167	143	6	anemic	anemic	ADJ
biomedich-167	143	7	activity	activity	NOUN
biomedich-167	143	8	of	of	ADP
biomedich-167	143	9	a	a	DET
biomedich-167	143	10	/	/	SYM
biomedich-167	143	11	l	l	NOUN
biomedich-167	143	12	/	/	SYM
biomedich-167	143	13	d	d	NOUN
biomedich-167	143	14	was	be	AUX
biomedich-167	143	15	best	good	ADJ
biomedich-167	143	16	when	when	SCONJ
biomedich-167	143	17	compared	compare	VERB
biomedich-167	143	18	to	to	ADP
biomedich-167	143	19	individual	individual	ADJ
biomedich-167	143	20	doses	dose	NOUN
biomedich-167	143	21	of	of	ADP
biomedich-167	143	22	a	a	DET
biomedich-167	143	23	/	/	SYM
biomedich-167	143	24	l	l	NOUN
biomedich-167	143	25	,	,	PUNCT
biomedich-167	144	1	d	d	PROPN
biomedich-167	144	2	and	and	CCONJ
biomedich-167	144	3	cq	cq	NOUN
biomedich-167	144	4	.	.	PROPN
biomedich-167	144	5	changes	change	NOUN
biomedich-167	144	6	in	in	ADP
biomedich-167	144	7	serum	serum	NOUN
biomedich-167	144	8	lipid	lipid	NOUN
biomedich-167	144	9	profile	profile	NOUN
biomedich-167	144	10	related	relate	VERB
biomedich-167	144	11	to	to	ADP
biomedich-167	144	12	malaria	malaria	NOUN
biomedich-167	144	13	infection	infection	NOUN
biomedich-167	144	14	have	have	AUX
biomedich-167	144	15	been	be	AUX
biomedich-167	144	16	reported	report	VERB
biomedich-167	144	17	in	in	ADP
biomedich-167	144	18	some	some	DET
biomedich-167	144	19	studies	study	NOUN
biomedich-167	144	20	.	.	PUNCT
biomedich-167	145	1	the	the	DET
biomedich-167	145	2	underlying	underlying	ADJ
biomedich-167	145	3	biological	biological	ADJ
biomedich-167	145	4	mechanisms	mechanism	NOUN
biomedich-167	145	5	for	for	ADP
biomedich-167	145	6	malaria	malaria	NOUN
biomedich-167	145	7	related	relate	VERB
biomedich-167	145	8	lipid	lipid	NOUN
biomedich-167	145	9	changes	change	NOUN
biomedich-167	145	10	remain	remain	VERB
biomedich-167	145	11	unclear	unclear	ADJ
biomedich-167	145	12	,	,	PUNCT
biomedich-167	145	13	but	but	CCONJ
biomedich-167	145	14	may	may	AUX
biomedich-167	145	15	be	be	AUX
biomedich-167	145	16	host	host	NOUN
biomedich-167	145	17	related	relate	VERB
biomedich-167	145	18	,	,	PUNCT
biomedich-167	145	19	parasite	parasite	NOUN
biomedich-167	145	20	-	-	PUNCT
biomedich-167	145	21	related	relate	VERB
biomedich-167	145	22	or	or	CCONJ
biomedich-167	145	23	a	a	DET
biomedich-167	145	24	combination	combination	NOUN
biomedich-167	145	25	of	of	ADP
biomedich-167	145	26	the	the	DET
biomedich-167	145	27	two	two	NUM
biomedich-167	145	28	factors	factor	NOUN
biomedich-167	145	29	(	(	PUNCT
biomedich-167	145	30	visser	visser	PROPN
biomedich-167	145	31	et	et	PROPN
biomedich-167	145	32	al	al	PROPN
biomedich-167	145	33	.	.	PROPN
biomedich-167	145	34	,	,	PUNCT
biomedich-167	145	35	2013	2013	NUM
biomedich-167	145	36	)	)	PUNCT
biomedich-167	145	37	.	.	PUNCT
biomedich-167	146	1	the	the	DET
biomedich-167	146	2	present	present	ADJ
biomedich-167	146	3	study	study	NOUN
biomedich-167	146	4	observed	observe	VERB
biomedich-167	146	5	significant	significant	ADJ
biomedich-167	146	6	alterations	alteration	NOUN
biomedich-167	146	7	in	in	ADP
biomedich-167	146	8	lipid	lipid	NOUN
biomedich-167	146	9	profile	profile	NOUN
biomedich-167	146	10	in	in	ADP
biomedich-167	146	11	parasitized	parasitize	VERB
biomedich-167	146	12	mice	mouse	NOUN
biomedich-167	146	13	marked	mark	VERB
biomedich-167	146	14	by	by	ADP
biomedich-167	146	15	increased	increase	VERB
biomedich-167	146	16	chol	chol	NOUN
biomedich-167	146	17	,	,	PUNCT
biomedich-167	146	18	tg	tg	X
biomedich-167	146	19	,	,	PUNCT
biomedich-167	146	20	ldl	ldl	NOUN
biomedich-167	146	21	-	-	PUNCT
biomedich-167	146	22	c	c	PROPN
biomedich-167	146	23	and	and	CCONJ
biomedich-167	146	24	decreased	decrease	VERB
biomedich-167	146	25	hdl	hdl	PROPN
biomedich-167	146	26	-	-	PUNCT
biomedich-167	146	27	c	c	NOUN
biomedich-167	146	28	levels	level	NOUN
biomedich-167	146	29	.	.	PUNCT
biomedich-167	147	1	the	the	DET
biomedich-167	147	2	altered	alter	VERB
biomedich-167	147	3	lipid	lipid	NOUN
biomedich-167	147	4	parameters	parameter	NOUN
biomedich-167	147	5	were	be	AUX
biomedich-167	147	6	best	well	ADV
biomedich-167	147	7	restored	restore	VERB
biomedich-167	147	8	in	in	ADP
biomedich-167	147	9	a	a	DET
biomedich-167	147	10	/	/	SYM
biomedich-167	147	11	l	l	NOUN
biomedich-167	147	12	/	/	SYM
biomedich-167	147	13	d	d	VERB
biomedich-167	147	14	-	-	PUNCT
biomedich-167	147	15	treated	treat	VERB
biomedich-167	147	16	mice	mouse	NOUN
biomedich-167	147	17	marked	mark	VERB
biomedich-167	147	18	by	by	ADP
biomedich-167	147	19	elevated	elevated	ADJ
biomedich-167	147	20	hdl	hdl	PROPN
biomedich-167	147	21	-	-	PUNCT
biomedich-167	147	22	c	c	PROPN
biomedich-167	147	23	and	and	CCONJ
biomedich-167	147	24	decreased	decrease	VERB
biomedich-167	147	25	chol	chol	NOUN
biomedich-167	147	26	,	,	PUNCT
biomedich-167	147	27	tg	tg	PRON
biomedich-167	147	28	,	,	PUNCT
biomedich-167	147	29	ldl	ldl	NOUN
biomedich-167	147	30	-	-	PUNCT
biomedich-167	147	31	c	c	NOUN
biomedich-167	147	32	levels	level	NOUN
biomedich-167	147	33	.	.	PUNCT
biomedich-167	148	1	the	the	DET
biomedich-167	148	2	observed	observe	VERB
biomedich-167	148	3	antiplasmodial	antiplasmodial	ADJ
biomedich-167	148	4	effect	effect	NOUN
biomedich-167	148	5	of	of	ADP
biomedich-167	148	6	a	a	DET
biomedich-167	148	7	/	/	SYM
biomedich-167	148	8	l	l	NOUN
biomedich-167	148	9	/	/	SYM
biomedich-167	148	10	d	d	NOUN
biomedich-167	148	11	may	may	AUX
biomedich-167	148	12	be	be	AUX
biomedich-167	148	13	due	due	ADJ
biomedich-167	148	14	to	to	ADP
biomedich-167	148	15	the	the	DET
biomedich-167	148	16	independent	independent	ADJ
biomedich-167	148	17	mechanisms	mechanism	NOUN
biomedich-167	148	18	of	of	ADP
biomedich-167	148	19	action	action	NOUN
biomedich-167	148	20	of	of	ADP
biomedich-167	148	21	the	the	DET
biomedich-167	148	22	constituent	constituent	ADJ
biomedich-167	148	23	drugs	drug	NOUN
biomedich-167	148	24	.	.	PUNCT
biomedich-167	149	1	the	the	DET
biomedich-167	149	2	antiplasmodial	antiplasmodial	ADJ
biomedich-167	149	3	mechanisms	mechanism	NOUN
biomedich-167	149	4	of	of	ADP
biomedich-167	149	5	d	d	NOUN
biomedich-167	149	6	are	be	AUX
biomedich-167	149	7	not	not	PART
biomedich-167	149	8	well	well	ADV
biomedich-167	149	9	defined	define	VERB
biomedich-167	149	10	,	,	PUNCT
biomedich-167	149	11	but	but	CCONJ
biomedich-167	149	12	d	d	NOUN
biomedich-167	149	13	can	can	AUX
biomedich-167	149	14	inhibit	inhibit	VERB
biomedich-167	149	15	mitochondrial	mitochondrial	ADJ
biomedich-167	149	16	protein	protein	NOUN
biomedich-167	149	17	synthesis	synthesis	NOUN
biomedich-167	149	18	and	and	CCONJ
biomedich-167	149	19	also	also	ADV
biomedich-167	149	20	decrease	decrease	VERB
biomedich-167	149	21	the	the	DET
biomedich-167	149	22	activity	activity	NOUN
biomedich-167	149	23	of	of	ADP
biomedich-167	149	24	mitochondrial	mitochondrial	ADJ
biomedich-167	149	25	enzyme	enzyme	NOUN
biomedich-167	149	26	(	(	PUNCT
biomedich-167	149	27	dihydroorotate	dihydroorotate	NOUN
biomedich-167	149	28	dehydrogenase	dehydrogenase	NOUN
biomedich-167	149	29	)	)	PUNCT
biomedich-167	149	30	involved	involve	VERB
biomedich-167	149	31	in	in	ADP
biomedich-167	149	32	pyrimidine	pyrimidine	NOUN
biomedich-167	149	33	synthesis	synthesis	NOUN
biomedich-167	149	34	(	(	PUNCT
biomedich-167	149	35	prapunwattana	prapunwattana	NOUN
biomedich-167	149	36	et	et	PROPN
biomedich-167	149	37	al	al	PROPN
biomedich-167	149	38	.	.	PROPN
biomedich-167	149	39	,	,	PUNCT
biomedich-167	149	40	1998	1998	NUM
biomedich-167	149	41	)	)	PUNCT
biomedich-167	149	42	.	.	PUNCT
biomedich-167	150	1	also	also	ADV
biomedich-167	150	2	,	,	PUNCT
biomedich-167	150	3	d	d	NOUN
biomedich-167	150	4	can	can	AUX
biomedich-167	150	5	inhibit	inhibit	VERB
biomedich-167	150	6	the	the	DET
biomedich-167	150	7	syntheses	synthesis	NOUN
biomedich-167	150	8	of	of	ADP
biomedich-167	150	9	nucleotides	nucleotide	NOUN
biomedich-167	150	10	and	and	CCONJ
biomedich-167	150	11	deoxynucleotides	deoxynucleotide	NOUN
biomedich-167	150	12	in	in	ADP
biomedich-167	150	13	plasmodium	plasmodium	NOUN
biomedich-167	150	14	(	(	PUNCT
biomedich-167	150	15	yeo	yeo	PROPN
biomedich-167	150	16	et	et	PROPN
biomedich-167	150	17	al	al	PROPN
biomedich-167	150	18	.	.	PROPN
biomedich-167	150	19	,	,	PUNCT
biomedich-167	150	20	1997	1997	NUM
biomedich-167	150	21	)	)	PUNCT
biomedich-167	150	22	.	.	PUNCT
biomedich-167	151	1	the	the	DET
biomedich-167	151	2	artemisinins	artemisinin	NOUN
biomedich-167	151	3	are	be	AUX
biomedich-167	151	4	speculated	speculate	VERB
biomedich-167	151	5	to	to	PART
biomedich-167	151	6	interfere	interfere	VERB
biomedich-167	151	7	with	with	ADP
biomedich-167	151	8	plasmodial	plasmodial	ADJ
biomedich-167	151	9	mitochondrial	mitochondrial	ADJ
biomedich-167	151	10	electron	electron	NOUN
biomedich-167	151	11	transport	transport	NOUN
biomedich-167	151	12	,	,	PUNCT
biomedich-167	151	13	transport	transport	NOUN
biomedich-167	151	14	proteins	protein	NOUN
biomedich-167	151	15	,	,	PUNCT
biomedich-167	151	16	and	and	CCONJ
biomedich-167	151	17	the	the	DET
biomedich-167	151	18	production	production	NOUN
biomedich-167	151	19	of	of	ADP
biomedich-167	151	20	free	free	ADJ
biomedich-167	151	21	radicals	radical	NOUN
biomedich-167	151	22	(	(	PUNCT
biomedich-167	151	23	stover	stover	NOUN
biomedich-167	151	24	et	et	PROPN
biomedich-167	151	25	al	al	PROPN
biomedich-167	151	26	.	.	PROPN
biomedich-167	151	27	,	,	PUNCT
biomedich-167	151	28	2012	2012	NUM
biomedich-167	151	29	)	)	PUNCT
biomedich-167	151	30	.	.	PUNCT
biomedich-167	152	1	lumefantrine	lumefantrine	NOUN
biomedich-167	152	2	is	be	AUX
biomedich-167	152	3	thought	think	VERB
biomedich-167	152	4	to	to	PART
biomedich-167	152	5	inhibit	inhibit	VERB
biomedich-167	152	6	β	β	NOUN
biomedich-167	152	7	-	-	PUNCT
biomedich-167	152	8	hematin	hematin	ADJ
biomedich-167	152	9	formation	formation	NOUN
biomedich-167	152	10	,	,	PUNCT
biomedich-167	152	11	an	an	DET
biomedich-167	152	12	important	important	ADJ
biomedich-167	152	13	detoxification	detoxification	NOUN
biomedich-167	152	14	pathway	pathway	NOUN
biomedich-167	152	15	in	in	ADP
biomedich-167	152	16	plasmodium	plasmodium	NOUN
biomedich-167	152	17	parasites	parasite	NOUN
biomedich-167	152	18	(	(	PUNCT
biomedich-167	152	19	stover	stover	NOUN
biomedich-167	152	20	et	et	PROPN
biomedich-167	152	21	al	al	PROPN
biomedich-167	152	22	.	.	PROPN
biomedich-167	152	23	,	,	PUNCT
biomedich-167	152	24	2012	2012	NUM
biomedich-167	152	25	)	)	PUNCT
biomedich-167	152	26	.	.	PUNCT
biomedich-167	153	1	conclusion	conclusion	NOUN
biomedich-167	153	2	results	result	NOUN
biomedich-167	153	3	of	of	ADP
biomedich-167	153	4	the	the	DET
biomedich-167	153	5	study	study	NOUN
biomedich-167	153	6	concluded	conclude	VERB
biomedich-167	153	7	that	that	SCONJ
biomedich-167	153	8	a	a	DET
biomedich-167	153	9	/	/	SYM
biomedich-167	153	10	l	l	NOUN
biomedich-167	153	11	/	/	SYM
biomedich-167	153	12	d	d	NOUN
biomedich-167	153	13	significantly	significantly	ADV
biomedich-167	153	14	decreased	decrease	VERB
biomedich-167	153	15	percentage	percentage	NOUN
biomedich-167	153	16	parasitemia	parasitemia	NOUN
biomedich-167	153	17	,	,	PUNCT
biomedich-167	153	18	increased	increase	VERB
biomedich-167	153	19	percentage	percentage	NOUN
biomedich-167	153	20	inhibition	inhibition	NOUN
biomedich-167	153	21	and	and	CCONJ
biomedich-167	153	22	prolonged	prolong	VERB
biomedich-167	153	23	mst	mst	PROPN
biomedich-167	153	24	in	in	ADP
biomedich-167	153	25	p.	p.	PROPN
biomedich-167	153	26	berghei	berghei	PROPN
biomedich-167	153	27	-	-	PUNCT
biomedich-167	153	28	infected	infect	VERB
biomedich-167	153	29	mice	mouse	NOUN
biomedich-167	153	30	.	.	PUNCT
biomedich-167	154	1	the	the	DET
biomedich-167	154	2	results	result	NOUN
biomedich-167	154	3	of	of	ADP
biomedich-167	154	4	this	this	DET
biomedich-167	154	5	study	study	NOUN
biomedich-167	154	6	therefore	therefore	ADV
biomedich-167	154	7	showed	show	VERB
biomedich-167	154	8	prospect	prospect	NOUN
biomedich-167	154	9	for	for	ADP
biomedich-167	154	10	the	the	DET
biomedich-167	154	11	use	use	NOUN
biomedich-167	154	12	of	of	ADP
biomedich-167	154	13	a	a	DET
biomedich-167	154	14	/	/	SYM
biomedich-167	154	15	l	l	NOUN
biomedich-167	154	16	/	/	SYM
biomedich-167	154	17	d	d	NOUN
biomedich-167	154	18	for	for	ADP
biomedich-167	154	19	malaria	malaria	NOUN
biomedich-167	154	20	treatment	treatment	NOUN
biomedich-167	154	21	.	.	PUNCT
biomedich-167	155	1	conflict	conflict	NOUN
biomedich-167	155	2	of	of	ADP
biomedich-167	155	3	interest	interest	NOUN
biomedich-167	155	4	:	:	PUNCT
biomedich-167	155	5	the	the	DET
biomedich-167	155	6	authors	author	NOUN
biomedich-167	155	7	declare	declare	VERB
biomedich-167	155	8	no	no	DET
biomedich-167	155	9	conflicts	conflict	NOUN
biomedich-167	155	10	of	of	ADP
biomedich-167	155	11	interest	interest	NOUN
biomedich-167	155	12	.	.	PUNCT
biomedich-167	156	1	references	reference	NOUN
biomedich-167	156	2	alecrim	alecrim	VERB
biomedich-167	156	3	mg	mg	PROPN
biomedich-167	156	4	,	,	PUNCT
biomedich-167	156	5	lacerda	lacerda	PROPN
biomedich-167	156	6	mv	mv	PROPN
biomedich-167	156	7	,	,	PUNCT
biomedich-167	156	8	mourao	mourao	PROPN
biomedich-167	156	9	mp	mp	PROPN
biomedich-167	156	10	,	,	PUNCT
biomedich-167	156	11	alecrim	alecrim	PROPN
biomedich-167	156	12	wd	wd	PROPN
biomedich-167	156	13	,	,	PUNCT
biomedich-167	156	14	padilha	padilha	VERB
biomedich-167	156	15	a	a	PRON
biomedich-167	156	16	,	,	PUNCT
biomedich-167	156	17	&	&	CCONJ
biomedich-167	156	18	cardoso	cardoso	PROPN
biomedich-167	156	19	bs	bs	PROPN
biomedich-167	156	20	.	.	PUNCT
biomedich-167	157	1	(	(	PUNCT
biomedich-167	157	2	2016	2016	NUM
biomedich-167	157	3	)	)	PUNCT
biomedich-167	157	4	.	.	PUNCT
biomedich-167	158	1	successful	successful	ADJ
biomedich-167	158	2	treatment	treatment	NOUN
biomedich-167	158	3	of	of	ADP
biomedich-167	158	4	plasmodium	plasmodium	NOUN
biomedich-167	158	5	falciparum	falciparum	ADJ
biomedich-167	158	6	malaria	malaria	NOUN
biomedich-167	158	7	with	with	ADP
biomedich-167	158	8	a	a	DET
biomedich-167	158	9	six	six	NUM
biomedich-167	158	10	-	-	PUNCT
biomedich-167	158	11	dose	dose	NOUN
biomedich-167	158	12	regimen	regiman	NOUN
biomedich-167	158	13	of	of	ADP
biomedich-167	158	14	artemetherlumefantrine	artemetherlumefantrine	NOUN
biomedich-167	158	15	versus	versus	ADP
biomedich-167	158	16	quinine	quinine	NOUN
biomedich-167	158	17	-	-	PUNCT
biomedich-167	158	18	doxycycline	doxycycline	NOUN
biomedich-167	158	19	in	in	ADP
biomedich-167	158	20	the	the	DET
biomedich-167	158	21	western	western	ADJ
biomedich-167	158	22	amazon	amazon	NOUN
biomedich-167	158	23	region	region	NOUN
biomedich-167	158	24	of	of	ADP
biomedich-167	158	25	brazil	brazil	PROPN
biomedich-167	158	26	.	.	PUNCT
biomedich-167	159	1	american	american	PROPN
biomedich-167	159	2	journal	journal	PROPN
biomedich-167	159	3	of	of	ADP
biomedich-167	159	4	tropical	tropical	ADJ
biomedich-167	159	5	medicine	medicine	NOUN
biomedich-167	159	6	and	and	CCONJ
biomedich-167	159	7	hygiene	hygiene	NOUN
biomedich-167	159	8	.	.	PUNCT
biomedich-167	160	1	74	74	NUM
biomedich-167	160	2	:	:	SYM
biomedich-167	160	3	20	20	NUM
biomedich-167	160	4	-	-	SYM
biomedich-167	160	5	5	5	NUM
biomedich-167	160	6	basco	basco	PROPN
biomedich-167	160	7	,	,	PUNCT
biomedich-167	160	8	l.	l.	PROPN
biomedich-167	160	9	k.	k.	PROPN
biomedich-167	160	10	,	,	PUNCT
biomedich-167	160	11	&	&	CCONJ
biomedich-167	160	12	le	le	PROPN
biomedich-167	160	13	bras	bras	PROPN
biomedich-167	160	14	j.	j.	PROPN
biomedich-167	160	15	(	(	PUNCT
biomedich-167	160	16	1993	1993	NUM
biomedich-167	160	17	)	)	PUNCT
biomedich-167	160	18	.	.	PUNCT
biomedich-167	161	1	activity	activity	NOUN
biomedich-167	161	2	in	in	ADP
biomedich-167	161	3	vitro	vitro	X
biomedich-167	161	4	of	of	ADP
biomedich-167	161	5	doxycycline	doxycycline	NOUN
biomedich-167	161	6	against	against	ADP
biomedich-167	161	7	multidrug	multidrug	NOUN
biomedich-167	161	8	-	-	PUNCT
biomedich-167	161	9	resistant	resistant	ADJ
biomedich-167	161	10	plasmodium	plasmodium	NOUN
biomedich-167	161	11	falciparum	falciparum	NOUN
biomedich-167	161	12	.	.	PUNCT
biomedich-167	162	1	transaction	transaction	NOUN
biomedich-167	162	2	of	of	ADP
biomedich-167	162	3	royal	royal	ADJ
biomedich-167	162	4	society	society	NOUN
biomedich-167	162	5	of	of	ADP
biomedich-167	162	6	tropical	tropical	ADJ
biomedich-167	162	7	medicine	medicine	NOUN
biomedich-167	162	8	and	and	CCONJ
biomedich-167	162	9	hygiene	hygiene	NOUN
biomedich-167	162	10	.	.	PUNCT
biomedich-167	163	1	87:469–470	87:469–470	NUM
biomedich-167	163	2	6	6	NUM
biomedich-167	163	3	biology	biology	NOUN
biomedich-167	163	4	,	,	PUNCT
biomedich-167	163	5	medicine	medicine	NOUN
biomedich-167	163	6	,	,	PUNCT
biomedich-167	163	7	&	&	CCONJ
biomedich-167	163	8	natural	natural	ADJ
biomedich-167	163	9	product	product	NOUN
biomedich-167	163	10	chemistry	chemistry	NOUN
biomedich-167	163	11	11	11	NUM
biomedich-167	163	12	(	(	PUNCT
biomedich-167	163	13	1	1	NUM
biomedich-167	163	14	)	)	PUNCT
biomedich-167	163	15	,	,	PUNCT
biomedich-167	163	16	2022	2022	NUM
biomedich-167	163	17	:	:	PUNCT
biomedich-167	163	18	1	1	NUM
biomedich-167	163	19	-	-	SYM
biomedich-167	163	20	6	6	NUM
biomedich-167	163	21	bobasa	bobasa	PROPN
biomedich-167	163	22	em	em	PRON
biomedich-167	163	23	,	,	PUNCT
biomedich-167	163	24	alemu	alemu	PROPN
biomedich-167	163	25	bg	bg	PROPN
biomedich-167	163	26	,	,	PUNCT
biomedich-167	163	27	berkessa	berkessa	NOUN
biomedich-167	163	28	st	st	PROPN
biomedich-167	163	29	,	,	PUNCT
biomedich-167	163	30	gemechu	gemechu	PROPN
biomedich-167	163	31	y	y	PROPN
biomedich-167	163	32	,	,	PUNCT
biomedich-167	163	33	fufa	fufa	PROPN
biomedich-167	163	34	fg	fg	PROPN
biomedich-167	163	35	,	,	PUNCT
biomedich-167	163	36	&	&	CCONJ
biomedich-167	163	37	cari	cari	PROPN
biomedich-167	163	38	gz	gz	PROPN
biomedich-167	163	39	et	et	PROPN
biomedich-167	163	40	al	al	PROPN
biomedich-167	163	41	.	.	PROPN
biomedich-167	163	42	2018	2018	NUM
biomedich-167	163	43	.	.	PUNCT
biomedich-167	164	1	antimalarial	antimalarial	ADJ
biomedich-167	164	2	activity	activity	NOUN
biomedich-167	164	3	of	of	ADP
biomedich-167	164	4	selected	select	VERB
biomedich-167	164	5	ethiopian	ethiopian	ADJ
biomedich-167	164	6	medicinal	medicinal	ADJ
biomedich-167	164	7	plants	plant	NOUN
biomedich-167	164	8	in	in	ADP
biomedich-167	164	9	mice	mouse	NOUN
biomedich-167	164	10	.	.	PUNCT
biomedich-167	165	1	journal	journal	PROPN
biomedich-167	165	2	of	of	ADP
biomedich-167	165	3	pharmacy	pharmacy	PROPN
biomedich-167	165	4	&	&	CCONJ
biomedich-167	165	5	pharmacognosy	pharmacognosy	PROPN
biomedich-167	165	6	research	research	NOUN
biomedich-167	165	7	,	,	PUNCT
biomedich-167	165	8	6	6	NUM
biomedich-167	165	9	(	(	PUNCT
biomedich-167	165	10	1	1	NUM
biomedich-167	165	11	)	)	PUNCT
biomedich-167	165	12	,	,	PUNCT
biomedich-167	165	13	57	57	NUM
biomedich-167	165	14	-	-	SYM
biomedich-167	165	15	64	64	NUM
biomedich-167	165	16	.	.	PUNCT
biomedich-167	166	1	cui	cui	PROPN
biomedich-167	166	2	l	l	NOUN
biomedich-167	166	3	,	,	PUNCT
biomedich-167	166	4	mharakurwa	mharakurwa	NOUN
biomedich-167	166	5	s	s	NOUN
biomedich-167	166	6	,	,	PUNCT
biomedich-167	166	7	ndiaye	ndiaye	NOUN
biomedich-167	166	8	d	d	PROPN
biomedich-167	166	9	,	,	PUNCT
biomedich-167	166	10	rathod	rathod	PROPN
biomedich-167	166	11	pk	pk	PROPN
biomedich-167	166	12	,	,	PUNCT
biomedich-167	166	13	&	&	CCONJ
biomedich-167	166	14	rosenthal	rosenthal	PROPN
biomedich-167	166	15	pj	pj	PROPN
biomedich-167	166	16	.	.	PUNCT
biomedich-167	166	17	(	(	PUNCT
biomedich-167	166	18	2015	2015	NUM
biomedich-167	166	19	)	)	PUNCT
biomedich-167	166	20	.	.	PUNCT
biomedich-167	167	1	antimalarial	antimalarial	ADJ
biomedich-167	167	2	drug	drug	PROPN
biomedich-167	167	3	resistance	resistance	PROPN
biomedich-167	167	4	literature	literature	PROPN
biomedich-167	167	5	review	review	NOUN
biomedich-167	167	6	and	and	CCONJ
biomedich-167	167	7	activities	activity	NOUN
biomedich-167	167	8	and	and	CCONJ
biomedich-167	167	9	finding	finding	NOUN
biomedich-167	167	10	of	of	ADP
biomedich-167	167	11	the	the	DET
biomedich-167	167	12	icemr	icemr	NOUN
biomedich-167	167	13	network	network	NOUN
biomedich-167	167	14	.	.	PUNCT
biomedich-167	168	1	american	american	PROPN
biomedich-167	168	2	journal	journal	PROPN
biomedich-167	168	3	of	of	ADP
biomedich-167	168	4	tropical	tropical	ADJ
biomedich-167	168	5	medicine	medicine	NOUN
biomedich-167	168	6	and	and	CCONJ
biomedich-167	168	7	hygiene	hygiene	NOUN
biomedich-167	168	8	.	.	PUNCT
biomedich-167	169	1	93(3):57–68	93(3):57–68	NUM
biomedich-167	169	2	gaillard	gaillard	PROPN
biomedich-167	169	3	t	t	PROPN
biomedich-167	169	4	,	,	PUNCT
biomedich-167	169	5	madamet	madamet	PROPN
biomedich-167	169	6	m	m	PROPN
biomedich-167	169	7	,	,	PUNCT
biomedich-167	169	8	&	&	CCONJ
biomedich-167	169	9	pradines	pradines	PROPN
biomedich-167	169	10	b.	b.	PROPN
biomedich-167	169	11	(	(	PUNCT
biomedich-167	169	12	2015	2015	NUM
biomedich-167	169	13	)	)	PUNCT
biomedich-167	169	14	.	.	PUNCT
biomedich-167	170	1	tetracyclines	tetracycline	NOUN
biomedich-167	170	2	in	in	ADP
biomedich-167	170	3	malaria	malaria	NOUN
biomedich-167	170	4	.	.	PUNCT
biomedich-167	171	1	malaria	malaria	PROPN
biomedich-167	171	2	journal	journal	PROPN
biomedich-167	171	3	.	.	PUNCT
biomedich-167	172	1	14	14	NUM
biomedich-167	172	2	,	,	PUNCT
biomedich-167	172	3	445	445	NUM
biomedich-167	172	4	;	;	PUNCT
biomedich-167	172	5	1	1	NUM
biomedich-167	172	6	-	-	SYM
biomedich-167	172	7	10	10	NUM
biomedich-167	172	8	.	.	PUNCT
biomedich-167	173	1	georgewill	georgewill	VERB
biomedich-167	173	2	ud	ud	PROPN
biomedich-167	173	3	,	,	PUNCT
biomedich-167	173	4	harold	harold	PROPN
biomedich-167	173	5	melford	melford	PROPN
biomedich-167	173	6	h	h	PROPN
biomedich-167	173	7	,	,	PUNCT
biomedich-167	173	8	&	&	CCONJ
biomedich-167	173	9	adikwu	adikwu	PROPN
biomedich-167	173	10	e	e	PROPN
biomedich-167	173	11	(	(	PUNCT
biomedich-167	173	12	2021	2021	NUM
biomedich-167	173	13	)	)	PUNCT
biomedich-167	173	14	.	.	PUNCT
biomedich-167	174	1	antiplasmodial	antiplasmodial	ADJ
biomedich-167	174	2	activity	activity	NOUN
biomedich-167	174	3	of	of	ADP
biomedich-167	174	4	artemether	artemether	ADJ
biomedich-167	174	5	-	-	PUNCT
biomedich-167	174	6	lumefantrine	lumefantrine	ADJ
biomedich-167	174	7	-	-	PUNCT
biomedich-167	174	8	tinidazole	tinidazole	NOUN
biomedich-167	174	9	on	on	ADP
biomedich-167	174	10	plasmodium	plasmodium	NOUN
biomedich-167	174	11	berghei	berghei	NOUN
biomedich-167	174	12	infected	infect	VERB
biomedich-167	174	13	mice	mouse	NOUN
biomedich-167	174	14	.	.	PUNCT
biomedich-167	175	1	the	the	DET
biomedich-167	175	2	pharmaceutical	pharmaceutical	ADJ
biomedich-167	175	3	and	and	CCONJ
biomedich-167	175	4	chemical	chemical	NOUN
biomedich-167	175	5	journal	journal	NOUN
biomedich-167	175	6	,	,	PUNCT
biomedich-167	175	7	2021	2021	NUM
biomedich-167	175	8	,	,	PUNCT
biomedich-167	175	9	8(1):107	8(1):107	NUM
biomedich-167	175	10	-	-	SYM
biomedich-167	175	11	113	113	NUM
biomedich-167	175	12	inbaneson	inbaneson	NOUN
biomedich-167	175	13	sj	sj	PROPN
biomedich-167	175	14	,	,	PUNCT
biomedich-167	175	15	&	&	CCONJ
biomedich-167	175	16	sundaram	sundaram	PROPN
biomedich-167	175	17	r.	r.	PROPN
biomedich-167	175	18	(	(	PUNCT
biomedich-167	175	19	2012	2012	NUM
biomedich-167	175	20	)	)	PUNCT
biomedich-167	175	21	.	.	PUNCT
biomedich-167	176	1	in	in	ADP
biomedich-167	176	2	vitro	vitro	X
biomedich-167	176	3	antiplasmodial	antiplasmodial	ADJ
biomedich-167	176	4	effect	effect	NOUN
biomedich-167	176	5	of	of	ADP
biomedich-167	176	6	ethanolic	ethanolic	ADJ
biomedich-167	176	7	extracts	extract	NOUN
biomedich-167	176	8	of	of	ADP
biomedich-167	176	9	traditional	traditional	ADJ
biomedich-167	176	10	medicinal	medicinal	ADJ
biomedich-167	176	11	plant	plant	NOUN
biomedich-167	176	12	ocimum	ocimum	ADJ
biomedich-167	176	13	species	specie	NOUN
biomedich-167	176	14	against	against	ADP
biomedich-167	176	15	plasmodium	plasmodium	NOUN
biomedich-167	176	16	falciparum	falciparum	NOUN
biomedich-167	176	17	.	.	PUNCT
biomedich-167	177	1	asian	asian	PROPN
biomedich-167	177	2	pacific	pacific	PROPN
biomedich-167	177	3	journal	journal	PROPN
biomedich-167	177	4	of	of	ADP
biomedich-167	177	5	tropical	tropical	ADJ
biomedich-167	177	6	medicine	medicine	NOUN
biomedich-167	177	7	5(2):103–106	5(2):103–106	NOUN
biomedich-167	177	8	.	.	PUNCT
biomedich-167	178	1	institute	institute	PROPN
biomedich-167	178	2	for	for	ADP
biomedich-167	178	3	laboratory	laboratory	NOUN
biomedich-167	178	4	animal	animal	NOUN
biomedich-167	178	5	research	research	NOUN
biomedich-167	178	6	(	(	PUNCT
biomedich-167	178	7	ilar	ilar	NOUN
biomedich-167	178	8	)	)	PUNCT
biomedich-167	178	9	.	.	PUNCT
biomedich-167	179	1	guide	guide	VERB
biomedich-167	179	2	for	for	ADP
biomedich-167	179	3	the	the	DET
biomedich-167	179	4	care	care	NOUN
biomedich-167	179	5	and	and	CCONJ
biomedich-167	179	6	use	use	NOUN
biomedich-167	179	7	of	of	ADP
biomedich-167	179	8	laboratory	laboratory	NOUN
biomedich-167	179	9	animals	animal	NOUN
biomedich-167	179	10	.	.	PUNCT
biomedich-167	180	1	8th	8th	ADJ
biomedich-167	180	2	ed	ed	NOUN
biomedich-167	180	3	.	.	PUNCT
biomedich-167	181	1	washington	washington	PROPN
biomedich-167	181	2	dc	dc	PROPN
biomedich-167	181	3	:	:	PUNCT
biomedich-167	181	4	national	national	PROPN
biomedich-167	181	5	academic	academic	ADJ
biomedich-167	181	6	press	press	NOUN
biomedich-167	181	7	;	;	PUNCT
biomedich-167	181	8	2011	2011	NUM
biomedich-167	181	9	.	.	PUNCT
biomedich-167	182	1	khan	khan	PROPN
biomedich-167	182	2	ma	ma	PROPN
biomedich-167	182	3	,	,	PUNCT
biomedich-167	182	4	smego	smego	PROPN
biomedich-167	182	5	ra	ra	PROPN
biomedich-167	182	6	jr	jr	PROPN
biomedich-167	182	7	,	,	PUNCT
biomedich-167	182	8	razi	razi	PROPN
biomedich-167	182	9	st	st	PROPN
biomedich-167	182	10	,	,	PUNCT
biomedich-167	182	11	&	&	CCONJ
biomedich-167	182	12	beg	beg	VERB
biomedich-167	182	13	ma	ma	PROPN
biomedich-167	182	14	.	.	PROPN
biomedich-167	182	15	(	(	PUNCT
biomedich-167	182	16	2004	2004	NUM
biomedich-167	182	17	)	)	PUNCT
biomedich-167	182	18	.	.	PUNCT
biomedich-167	183	1	emerging	emerge	VERB
biomedich-167	183	2	drug	drug	NOUN
biomedich-167	183	3	--	--	PUNCT
biomedich-167	183	4	resistance	resistance	NOUN
biomedich-167	183	5	and	and	CCONJ
biomedich-167	183	6	guidelines	guideline	NOUN
biomedich-167	183	7	for	for	ADP
biomedich-167	183	8	treatment	treatment	NOUN
biomedich-167	183	9	of	of	ADP
biomedich-167	183	10	malaria	malaria	NOUN
biomedich-167	183	11	.	.	PUNCT
biomedich-167	184	1	journal	journal	NOUN
biomedich-167	184	2	of	of	ADP
biomedich-167	184	3	the	the	DET
biomedich-167	184	4	college	college	PROPN
biomedich-167	184	5	of	of	ADP
biomedich-167	184	6	physicians	physician	NOUN
biomedich-167	184	7	and	and	CCONJ
biomedich-167	184	8	surgeons	surgeon	NOUN
biomedich-167	184	9	of	of	ADP
biomedich-167	184	10	pakistan.14	pakistan.14	NOUN
biomedich-167	184	11	:	:	PUNCT
biomedich-167	184	12	31924	31924	NUM
biomedich-167	184	13	knight	knight	NOUN
biomedich-167	184	14	,	,	PUNCT
biomedich-167	184	15	d.j	d.j	PROPN
biomedich-167	184	16	,	,	PUNCT
biomedich-167	184	17	&	&	CCONJ
biomedich-167	184	18	peters	peters	PROPN
biomedich-167	184	19	,	,	PUNCT
biomedich-167	184	20	w.	w.	PROPN
biomedich-167	184	21	(	(	PUNCT
biomedich-167	184	22	1980	1980	NUM
biomedich-167	184	23	)	)	PUNCT
biomedich-167	184	24	.	.	PUNCT
biomedich-167	185	1	the	the	DET
biomedich-167	185	2	antimalarial	antimalarial	ADJ
biomedich-167	185	3	action	action	NOUN
biomedich-167	185	4	of	of	ADP
biomedich-167	185	5	nbenzyl	nbenzyl	NOUN
biomedich-167	185	6	oxydihydrotriazines	oxydihydrotriazine	NOUN
biomedich-167	185	7	and	and	CCONJ
biomedich-167	185	8	the	the	DET
biomedich-167	185	9	studies	study	NOUN
biomedich-167	185	10	on	on	ADP
biomedich-167	185	11	its	its	PRON
biomedich-167	185	12	mode	mode	NOUN
biomedich-167	185	13	of	of	ADP
biomedich-167	185	14	action	action	NOUN
biomedich-167	185	15	.	.	PUNCT
biomedich-167	186	1	ann	ann	PROPN
biomedich-167	186	2	of	of	ADP
biomedich-167	186	3	tropical	tropical	ADJ
biomedich-167	186	4	medicine	medicine	NOUN
biomedich-167	186	5	and	and	CCONJ
biomedich-167	186	6	parasitology	parasitology	NOUN
biomedich-167	186	7	.	.	PUNCT
biomedich-167	187	1	74	74	NUM
biomedich-167	187	2	:	:	SYM
biomedich-167	187	3	393404	393404	NUM
biomedich-167	187	4	.	.	PUNCT
biomedich-167	188	1	miller	miller	PROPN
biomedich-167	188	2	rs	rs	PROPN
biomedich-167	188	3	,	,	PUNCT
biomedich-167	188	4	wongrichanalai	wongrichanalai	VERB
biomedich-167	188	5	c	c	PROPN
biomedich-167	188	6	,	,	PUNCT
biomedich-167	188	7	buathong	buathong	NOUN
biomedich-167	188	8	n	n	CCONJ
biomedich-167	188	9	,	,	PUNCT
biomedich-167	188	10	mcdaniel	mcdaniel	PROPN
biomedich-167	188	11	p	p	PROPN
biomedich-167	188	12	,	,	PUNCT
biomedich-167	188	13	walsh	walsh	NOUN
biomedich-167	188	14	ds	ds	PROPN
biomedich-167	188	15	,	,	PUNCT
biomedich-167	188	16	&	&	CCONJ
biomedich-167	188	17	knirsch	knirsch	PROPN
biomedich-167	188	18	c	c	PROPN
biomedich-167	188	19	(	(	PUNCT
biomedich-167	188	20	2006	2006	NUM
biomedich-167	188	21	)	)	PUNCT
biomedich-167	188	22	.	.	PUNCT
biomedich-167	189	1	effective	effective	ADJ
biomedich-167	189	2	treatment	treatment	NOUN
biomedich-167	189	3	of	of	ADP
biomedich-167	189	4	uncomplicated	uncomplicated	ADJ
biomedich-167	189	5	plasmodium	plasmodium	NOUN
biomedich-167	189	6	falciparum	falciparum	ADJ
biomedich-167	189	7	malaria	malaria	NOUN
biomedich-167	189	8	with	with	ADP
biomedich-167	189	9	azithromycin	azithromycin	NOUN
biomedich-167	189	10	-	-	PUNCT
biomedich-167	189	11	quinine	quinine	NOUN
biomedich-167	189	12	combinations	combination	NOUN
biomedich-167	189	13	:	:	PUNCT
biomedich-167	189	14	a	a	DET
biomedich-167	189	15	randomized	randomized	ADJ
biomedich-167	189	16	,	,	PUNCT
biomedich-167	189	17	doseranging	doserange	VERB
biomedich-167	189	18	study	study	NOUN
biomedich-167	189	19	.	.	PUNCT
biomedich-167	190	1	american	american	PROPN
biomedich-167	190	2	journal	journal	PROPN
biomedich-167	190	3	of	of	ADP
biomedich-167	190	4	tropical	tropical	ADJ
biomedich-167	190	5	medicine	medicine	NOUN
biomedich-167	190	6	and	and	CCONJ
biomedich-167	190	7	hygiene	hygiene	NOUN
biomedich-167	190	8	.	.	PUNCT
biomedich-167	191	1	74	74	NUM
biomedich-167	191	2	:	:	SYM
biomedich-167	191	3	401	401	NUM
biomedich-167	191	4	-	-	SYM
biomedich-167	191	5	6	6	NUM
biomedich-167	191	6	nardos	nardo	NOUN
biomedich-167	191	7	a	a	PRON
biomedich-167	191	8	,	,	PUNCT
biomedich-167	191	9	&	&	CCONJ
biomedich-167	191	10	makonnen	makonnen	PROPN
biomedich-167	191	11	e.	e.	PROPN
biomedich-167	191	12	(	(	PUNCT
biomedich-167	191	13	2017	2017	NUM
biomedich-167	191	14	)	)	PUNCT
biomedich-167	191	15	.	.	PUNCT
biomedich-167	192	1	in	in	ADP
biomedich-167	192	2	vivo	vivo	ADJ
biomedich-167	192	3	antiplasmodial	antiplasmodial	ADJ
biomedich-167	192	4	activity	activity	NOUN
biomedich-167	192	5	and	and	CCONJ
biomedich-167	192	6	toxicological	toxicological	ADJ
biomedich-167	192	7	assessment	assessment	NOUN
biomedich-167	192	8	of	of	ADP
biomedich-167	192	9	hydroethanolic	hydroethanolic	ADJ
biomedich-167	192	10	crude	crude	ADJ
biomedich-167	192	11	extract	extract	NOUN
biomedich-167	192	12	of	of	ADP
biomedich-167	192	13	ajuga	ajuga	PROPN
biomedich-167	192	14	remota	remota	PROPN
biomedich-167	192	15	.	.	PUNCT
biomedich-167	193	1	malaria	malaria	PROPN
biomedich-167	193	2	journal	journal	PROPN
biomedich-167	193	3	.	.	PUNCT
biomedich-167	194	1	16:25	16:25	NUM
biomedich-167	194	2	;	;	PUNCT
biomedich-167	194	3	1	1	NUM
biomedich-167	194	4	-	-	SYM
biomedich-167	194	5	8	8	NUM
biomedich-167	194	6	nsanzabana	nsanzabana	ADJ
biomedich-167	194	7	c.	c.	NOUN
biomedich-167	194	8	(	(	PUNCT
biomedich-167	194	9	2019	2019	NUM
biomedich-167	194	10	)	)	PUNCT
biomedich-167	194	11	.	.	PUNCT
biomedich-167	195	1	resistance	resistance	NOUN
biomedich-167	195	2	to	to	ADP
biomedich-167	195	3	artemisinin	artemisinin	PROPN
biomedich-167	195	4	combination	combination	NOUN
biomedich-167	195	5	therapies	therapy	NOUN
biomedich-167	195	6	(	(	PUNCT
biomedich-167	195	7	acts	act	NOUN
biomedich-167	195	8	):	):	PUNCT
biomedich-167	195	9	do	do	AUX
biomedich-167	195	10	not	not	PART
biomedich-167	195	11	forget	forget	VERB
biomedich-167	195	12	the	the	DET
biomedich-167	195	13	partner	partner	NOUN
biomedich-167	195	14	drug	drug	NOUN
biomedich-167	195	15	!	!	PUNCT
biomedich-167	196	1	tropical	tropical	ADJ
biomedich-167	196	2	medicine	medicine	NOUN
biomedich-167	196	3	and	and	CCONJ
biomedich-167	196	4	infectious	infectious	ADJ
biomedich-167	196	5	disease	disease	NOUN
biomedich-167	196	6	.	.	PUNCT
biomedich-167	197	1	4	4	NUM
biomedich-167	197	2	,	,	PUNCT
biomedich-167	197	3	26;1	26;1	NUM
biomedich-167	197	4	-	-	SYM
biomedich-167	197	5	11	11	NUM
biomedich-167	197	6	oliveira	oliveira	PROPN
biomedich-167	197	7	ab	ab	PROPN
biomedich-167	197	8	,	,	PUNCT
biomedich-167	197	9	dolabela	dolabela	PROPN
biomedich-167	197	10	mf	mf	PROPN
biomedich-167	197	11	,	,	PUNCT
biomedich-167	197	12	braga	braga	PROPN
biomedich-167	197	13	fc	fc	PROPN
biomedich-167	197	14	,	,	PUNCT
biomedich-167	197	15	jácome	jácome	PROPN
biomedich-167	197	16	rlrp	rlrp	NOUN
biomedich-167	197	17	,	,	PUNCT
biomedich-167	197	18	varotti	varotti	PROPN
biomedich-167	197	19	fp	fp	PROPN
biomedich-167	197	20	,	,	PUNCT
biomedich-167	197	21	&	&	CCONJ
biomedich-167	197	22	póvoa	póvoa	PROPN
biomedich-167	197	23	mm	mm	PROPN
biomedich-167	197	24	.	.	PUNCT
biomedich-167	197	25	(	(	PUNCT
biomedich-167	197	26	2009	2009	NUM
biomedich-167	197	27	)	)	PUNCT
biomedich-167	197	28	.	.	PUNCT
biomedich-167	198	1	antimalarial	antimalarial	ADJ
biomedich-167	198	2	agents	agent	NOUN
biomedich-167	198	3	:	:	PUNCT
biomedich-167	198	4	new	new	ADJ
biomedich-167	198	5	leads	lead	NOUN
biomedich-167	198	6	and	and	CCONJ
biomedich-167	198	7	efficient	efficient	ADJ
biomedich-167	198	8	phythomedicines	phythomedicine	NOUN
biomedich-167	198	9	.	.	PUNCT
biomedich-167	199	1	part	part	NOUN
biomedich-167	199	2	i.	i.	PROPN
biomedich-167	199	3	alkaloids	alkaloids	PROPN
biomedich-167	199	4	.	.	PUNCT
biomedich-167	199	5	anais	anais	PROPN
biomedich-167	199	6	da	da	PROPN
biomedich-167	199	7	academia	academia	PROPN
biomedich-167	199	8	brasileira	brasileira	PROPN
biomedich-167	199	9	de	de	PROPN
biomedich-167	199	10	ciências	ciências	PROPN
biomedich-167	199	11	.	.	PUNCT
biomedich-167	200	1	81:715–40	81:715–40	NUM
biomedich-167	200	2	.	.	PUNCT
biomedich-167	201	1	peters	peters	PROPN
biomedich-167	201	2	,	,	PUNCT
biomedich-167	201	3	w.	w.	PROPN
biomedich-167	201	4	(	(	PUNCT
biomedich-167	201	5	1967	1967	NUM
biomedich-167	201	6	)	)	PUNCT
biomedich-167	201	7	.	.	PUNCT
biomedich-167	202	1	rational	rational	ADJ
biomedich-167	202	2	methods	method	NOUN
biomedich-167	202	3	in	in	ADP
biomedich-167	202	4	the	the	DET
biomedich-167	202	5	search	search	NOUN
biomedich-167	202	6	for	for	ADP
biomedich-167	202	7	antimalarial	antimalarial	ADJ
biomedich-167	202	8	drugs	drug	NOUN
biomedich-167	202	9	.	.	PUNCT
biomedich-167	203	1	transaction	transaction	NOUN
biomedich-167	203	2	of	of	ADP
biomedich-167	203	3	royal	royal	PROPN
biomedich-167	203	4	.	.	PUNCT
biomedich-167	204	1	society	society	NOUN
biomedich-167	204	2	of	of	ADP
biomedich-167	204	3	tropical	tropical	ADJ
biomedich-167	204	4	medicine	medicine	NOUN
biomedich-167	204	5	and	and	CCONJ
biomedich-167	204	6	hygiene	hygiene	NOUN
biomedich-167	204	7	.	.	PUNCT
biomedich-167	205	1	61	61	NUM
biomedich-167	205	2	:	:	SYM
biomedich-167	205	3	400	400	NUM
biomedich-167	205	4	-	-	SYM
biomedich-167	205	5	410	410	NUM
biomedich-167	205	6	.	.	PUNCT
biomedich-167	206	1	prapunwattana	prapunwattana	PROPN
biomedich-167	206	2	p	p	X
biomedich-167	206	3	,	,	PUNCT
biomedich-167	206	4	o’sullivan	o’sullivan	PROPN
biomedich-167	206	5	wj	wj	PROPN
biomedich-167	206	6	,	,	PUNCT
biomedich-167	206	7	&	&	CCONJ
biomedich-167	206	8	yuthavong	yuthavong	PROPN
biomedich-167	206	9	y.	y.	PROPN
biomedich-167	206	10	(	(	PUNCT
biomedich-167	206	11	1988	1988	NUM
biomedich-167	206	12	)	)	PUNCT
biomedich-167	206	13	.	.	PUNCT
biomedich-167	207	1	depression	depression	NOUN
biomedich-167	207	2	of	of	ADP
biomedich-167	207	3	plasmodium	plasmodium	NOUN
biomedich-167	207	4	falciparum	falciparum	ADJ
biomedich-167	207	5	dihydroorotate	dihydroorotate	NOUN
biomedich-167	207	6	dehydrogenase	dehydrogenase	NOUN
biomedich-167	207	7	activity	activity	NOUN
biomedich-167	207	8	in	in	ADP
biomedich-167	207	9	in	in	ADP
biomedich-167	207	10	vitro	vitro	X
biomedich-167	207	11	culture	culture	NOUN
biomedich-167	207	12	by	by	ADP
biomedich-167	207	13	tetracycline	tetracycline	NOUN
biomedich-167	207	14	.	.	PUNCT
biomedich-167	208	1	molecular	molecular	ADJ
biomedich-167	208	2	and	and	CCONJ
biomedich-167	208	3	biochemical	biochemical	ADJ
biomedich-167	208	4	parasitology	parasitology	NOUN
biomedich-167	208	5	.	.	PUNCT
biomedich-167	209	1	27:119–24	27:119–24	PROPN
biomedich-167	209	2	.	.	PUNCT
biomedich-167	210	1	ryley	ryley	PROPN
biomedich-167	210	2	,	,	PUNCT
biomedich-167	210	3	j.f	j.f	PROPN
biomedich-167	210	4	,	,	PUNCT
biomedich-167	210	5	&	&	CCONJ
biomedich-167	210	6	peters	peters	PROPN
biomedich-167	210	7	,	,	PUNCT
biomedich-167	210	8	w.	w.	PROPN
biomedich-167	210	9	(	(	PUNCT
biomedich-167	210	10	1970	1970	NUM
biomedich-167	210	11	)	)	PUNCT
biomedich-167	210	12	.	.	PUNCT
biomedich-167	211	1	the	the	DET
biomedich-167	211	2	antimalarial	antimalarial	ADJ
biomedich-167	211	3	activity	activity	NOUN
biomedich-167	211	4	of	of	ADP
biomedich-167	211	5	some	some	DET
biomedich-167	211	6	quinolone	quinolone	ADJ
biomedich-167	211	7	esters	ester	NOUN
biomedich-167	211	8	.	.	PUNCT
biomedich-167	212	1	annals	annal	NOUN
biomedich-167	212	2	of	of	ADP
biomedich-167	212	3	tropical	tropical	ADJ
biomedich-167	212	4	medicine	medicine	NOUN
biomedich-167	212	5	and	and	CCONJ
biomedich-167	212	6	parasitology	parasitology	NOUN
biomedich-167	212	7	.	.	PUNCT
biomedich-167	213	1	84	84	NUM
biomedich-167	213	2	:	:	PUNCT
biomedich-167	213	3	209	209	NUM
biomedich-167	213	4	-	-	SYM
biomedich-167	213	5	222	222	NUM
biomedich-167	213	6	.	.	PUNCT
biomedich-167	214	1	schmidt	schmidt	PROPN
biomedich-167	214	2	ke	ke	PROPN
biomedich-167	214	3	,	,	PUNCT
biomedich-167	214	4	kuepper	kuepper	PROPN
biomedich-167	214	5	jm	jm	PROPN
biomedich-167	214	6	,	,	PUNCT
biomedich-167	214	7	schumak	schumak	PROPN
biomedich-167	214	8	b	b	NOUN
biomedich-167	214	9	,	,	PUNCT
biomedich-167	214	10	alferink	alferink	PROPN
biomedich-167	214	11	j	j	PROPN
biomedich-167	214	12	,	,	PUNCT
biomedich-167	214	13	hofmann	hofmann	PROPN
biomedich-167	214	14	a	a	PRON
biomedich-167	214	15	,	,	PUNCT
biomedich-167	214	16	&	&	CCONJ
biomedich-167	214	17	hawland	hawland	PROPN
biomedich-167	214	18	sw	sw	PROPN
biomedich-167	214	19	(	(	PUNCT
biomedich-167	214	20	2018	2018	NUM
biomedich-167	214	21	)	)	PUNCT
biomedich-167	214	22	.	.	PUNCT
biomedich-167	215	1	doxycycline	doxycycline	NOUN
biomedich-167	215	2	inhibits	inhibit	VERB
biomedich-167	215	3	experimental	experimental	ADJ
biomedich-167	215	4	cerebral	cerebral	ADJ
biomedich-167	215	5	malaria	malaria	NOUN
biomedich-167	215	6	by	by	ADP
biomedich-167	215	7	reducing	reduce	VERB
biomedich-167	215	8	inflammatory	inflammatory	ADJ
biomedich-167	215	9	immune	immune	ADJ
biomedich-167	215	10	reactions	reaction	NOUN
biomedich-167	215	11	and	and	CCONJ
biomedich-167	215	12	tissue	tissue	NOUN
biomedich-167	215	13	-	-	PUNCT
biomedich-167	215	14	degrading	degrade	VERB
biomedich-167	215	15	mediators	mediator	NOUN
biomedich-167	215	16	.	.	PUNCT
biomedich-167	216	1	public	public	ADJ
biomedich-167	216	2	library	library	NOUN
biomedich-167	216	3	of	of	ADP
biomedich-167	216	4	science	science	PROPN
biomedich-167	216	5	one	one	NUM
biomedich-167	216	6	.	.	PUNCT
biomedich-167	217	1	13	13	NUM
biomedich-167	217	2	:	:	PUNCT
biomedich-167	217	3	e0192717	e0192717	NOUN
biomedich-167	217	4	.	.	PUNCT
biomedich-167	218	1	sirima	sirima	PROPN
biomedich-167	218	2	sb	sb	PROPN
biomedich-167	218	3	,	,	PUNCT
biomedich-167	218	4	ogutu	ogutu	PROPN
biomedich-167	218	5	b	b	PROPN
biomedich-167	218	6	,	,	PUNCT
biomedich-167	218	7	&	&	CCONJ
biomedich-167	218	8	lusingu	lusingu	PROPN
biomedich-167	218	9	jpa	jpa	PROPN
biomedich-167	218	10	.	.	PUNCT
biomedich-167	219	1	(	(	PUNCT
biomedich-167	219	2	2016	2016	NUM
biomedich-167	219	3	)	)	PUNCT
biomedich-167	219	4	.	.	PUNCT
biomedich-167	220	1	comparison	comparison	NOUN
biomedich-167	220	2	of	of	ADP
biomedich-167	220	3	artesunate	artesunate	NOUN
biomedich-167	220	4	-	-	PUNCT
biomedich-167	220	5	mefloquine	mefloquine	NOUN
biomedich-167	220	6	and	and	CCONJ
biomedich-167	220	7	artemether	artemether	ADJ
biomedich-167	220	8	-	-	PUNCT
biomedich-167	220	9	lumefantrine	lumefantrine	ADJ
biomedich-167	220	10	fixeddose	fixeddose	ADJ
biomedich-167	220	11	combinations	combination	NOUN
biomedich-167	220	12	for	for	ADP
biomedich-167	220	13	treatment	treatment	NOUN
biomedich-167	220	14	of	of	ADP
biomedich-167	220	15	uncomplicated	uncomplicated	ADJ
biomedich-167	220	16	plasmodium	plasmodium	NOUN
biomedich-167	220	17	falciparum	falciparum	ADJ
biomedich-167	220	18	malaria	malaria	NOUN
biomedich-167	220	19	in	in	ADP
biomedich-167	220	20	children	child	NOUN
biomedich-167	220	21	younger	young	ADJ
biomedich-167	220	22	than	than	ADP
biomedich-167	220	23	5	5	NUM
biomedich-167	220	24	years	year	NOUN
biomedich-167	220	25	in	in	ADP
biomedich-167	220	26	sub	sub	ADJ
biomedich-167	220	27	-	-	ADJ
biomedich-167	220	28	saharan	saharan	ADJ
biomedich-167	220	29	africa	africa	PROPN
biomedich-167	220	30	:	:	PUNCT
biomedich-167	220	31	a	a	DET
biomedich-167	220	32	randomised	randomised	ADJ
biomedich-167	220	33	,	,	PUNCT
biomedich-167	220	34	multicentre	multicentre	NOUN
biomedich-167	220	35	,	,	PUNCT
biomedich-167	220	36	phase	phase	NOUN
biomedich-167	220	37	4	4	NUM
biomedich-167	220	38	trial	trial	NOUN
biomedich-167	220	39	.	.	PUNCT
biomedich-167	221	1	lancet	lancet	VERB
biomedich-167	221	2	infectious	infectious	ADJ
biomedich-167	221	3	disease	disease	NOUN
biomedich-167	221	4	.	.	PUNCT
biomedich-167	222	1	16(10):1123	16(10):1123	NUM
biomedich-167	222	2	-	-	SYM
biomedich-167	222	3	1133	1133	NUM
biomedich-167	222	4	.	.	PUNCT
biomedich-167	223	1	somsak	somsak	PROPN
biomedich-167	223	2	v	v	NOUN
biomedich-167	223	3	,	,	PUNCT
biomedich-167	223	4	damkaew	damkaew	VERB
biomedich-167	223	5	a	a	PRON
biomedich-167	223	6	,	,	PUNCT
biomedich-167	223	7	&	&	CCONJ
biomedich-167	223	8	onrak	onrak	PROPN
biomedich-167	224	1	p.	p.	PROPN
biomedich-167	224	2	(	(	PUNCT
biomedich-167	224	3	2018	2018	NUM
biomedich-167	224	4	)	)	PUNCT
biomedich-167	224	5	.	.	PUNCT
biomedich-167	225	1	antimalarial	antimalarial	ADJ
biomedich-167	225	2	activity	activity	NOUN
biomedich-167	225	3	of	of	ADP
biomedich-167	225	4	kaempferol	kaempferol	NOUN
biomedich-167	225	5	and	and	CCONJ
biomedich-167	225	6	its	its	PRON
biomedich-167	225	7	combination	combination	NOUN
biomedich-167	225	8	with	with	ADP
biomedich-167	225	9	chloroquine	chloroquine	NOUN
biomedich-167	225	10	in	in	ADP
biomedich-167	225	11	plasmodium	plasmodium	NOUN
biomedich-167	225	12	berghei	berghei	NOUN
biomedich-167	225	13	infection	infection	NOUN
biomedich-167	225	14	in	in	ADP
biomedich-167	225	15	mice	mouse	NOUN
biomedich-167	225	16	.	.	PUNCT
biomedich-167	226	1	journal	journal	PROPN
biomedich-167	226	2	of	of	ADP
biomedich-167	226	3	pathology	pathology	PROPN
biomedich-167	226	4	2018	2018	NUM
biomedich-167	226	5	;	;	PUNCT
biomedich-167	226	6	2018;17	2018;17	NUM
biomedich-167	226	7	stover	stover	NOUN
biomedich-167	226	8	kr	kr	PROPN
biomedich-167	226	9	,	,	PUNCT
biomedich-167	226	10	king	king	PROPN
biomedich-167	226	11	st	st	PROPN
biomedich-167	226	12	,	,	PUNCT
biomedich-167	226	13	&	&	CCONJ
biomedich-167	226	14	robinson	robinson	PROPN
biomedich-167	226	15	j.	j.	PROPN
biomedich-167	226	16	(	(	PUNCT
biomedich-167	226	17	2012	2012	NUM
biomedich-167	226	18	)	)	PUNCT
biomedich-167	226	19	.	.	PUNCT
biomedich-167	227	1	artemetherlumefantrine	artemetherlumefantrine	NOUN
biomedich-167	227	2	:	:	PUNCT
biomedich-167	227	3	an	an	DET
biomedich-167	227	4	option	option	NOUN
biomedich-167	227	5	for	for	ADP
biomedich-167	227	6	malaria	malaria	NOUN
biomedich-167	227	7	.	.	PUNCT
biomedich-167	228	1	annalsof	annalsof	VERB
biomedich-167	228	2	pharmacotherapy	pharmacotherapy	NOUN
biomedich-167	228	3	.	.	PUNCT
biomedich-167	229	1	46(4):567	46(4):567	NUM
biomedich-167	229	2	-	-	NOUN
biomedich-167	229	3	77	77	NUM
biomedich-167	229	4	.	.	PUNCT
biomedich-167	230	1	unekwuojo	unekwuojo	ADJ
biomedich-167	230	2	eg	eg	NOUN
biomedich-167	230	3	,	,	PUNCT
biomedich-167	230	4	james	james	PROPN
biomedich-167	230	5	o	o	PROPN
biomedich-167	230	6	,	,	PUNCT
biomedich-167	230	7	&	&	CCONJ
biomedich-167	230	8	olubunmi	olubunmi	PROPN
biomedich-167	230	9	ar	ar	PROPN
biomedich-167	230	10	.	.	PROPN
biomedich-167	230	11	(	(	PUNCT
biomedich-167	230	12	2011	2011	NUM
biomedich-167	230	13	)	)	PUNCT
biomedich-167	230	14	.	.	PUNCT
biomedich-167	231	1	suppressive	suppressive	NOUN
biomedich-167	231	2	,	,	PUNCT
biomedich-167	231	3	curative	curative	ADJ
biomedich-167	231	4	and	and	CCONJ
biomedich-167	231	5	prophylactic	prophylactic	ADJ
biomedich-167	231	6	potentials	potential	NOUN
biomedich-167	231	7	of	of	ADP
biomedich-167	231	8	morinda	morinda	PROPN
biomedich-167	231	9	lucida	lucida	PROPN
biomedich-167	231	10	(	(	PUNCT
biomedich-167	231	11	benth	benth	PROPN
biomedich-167	231	12	)	)	PUNCT
biomedich-167	231	13	against	against	ADP
biomedich-167	231	14	,	,	PUNCT
biomedich-167	231	15	erythrocytic	erythrocytic	ADJ
biomedich-167	231	16	stage	stage	NOUN
biomedich-167	231	17	of	of	ADP
biomedich-167	231	18	mice	mouse	NOUN
biomedich-167	231	19	infected	infect	VERB
biomedich-167	231	20	with	with	ADP
biomedich-167	231	21	chloroquine	chloroquine	NOUN
biomedich-167	231	22	sensitive	sensitive	ADJ
biomedich-167	231	23	plasmodium	plasmodium	NOUN
biomedich-167	231	24	berghei	berghei	PROPN
biomedich-167	231	25	.	.	PUNCT
biomedich-167	232	1	british	british	PROPN
biomedich-167	232	2	journal	journal	PROPN
biomedich-167	232	3	of	of	ADP
biomedich-167	232	4	applied	apply	VERB
biomedich-167	232	5	science	science	NOUN
biomedich-167	232	6	and	and	CCONJ
biomedich-167	232	7	technology	technology	NOUN
biomedich-167	232	8	.	.	PUNCT
biomedich-167	233	1	1(3):131	1(3):131	NUM
biomedich-167	233	2	-	-	SYM
biomedich-167	233	3	40	40	NUM
biomedich-167	233	4	visser	visser	PROPN
biomedich-167	233	5	b.j	b.j	PROPN
biomedich-167	233	6	,	,	PUNCT
biomedich-167	233	7	wieten	wieten	VERB
biomedich-167	233	8	r.w	r.w	PROPN
biomedich-167	233	9	,	,	PUNCT
biomedich-167	233	10	nagel	nagel	PROPN
biomedich-167	233	11	i.m	i.m	PROPN
biomedich-167	233	12	.	.	PROPN
biomedich-167	233	13	&	&	CCONJ
biomedich-167	233	14	grobusch	grobusch	PROPN
biomedich-167	233	15	mp	mp	PROPN
biomedich-167	233	16	.	.	PUNCT
biomedich-167	234	1	(	(	PUNCT
biomedich-167	234	2	2013	2013	NUM
biomedich-167	234	3	)	)	PUNCT
biomedich-167	234	4	.	.	PUNCT
biomedich-167	235	1	serum	serum	NOUN
biomedich-167	235	2	lipids	lipid	NOUN
biomedich-167	235	3	and	and	CCONJ
biomedich-167	235	4	lipoproteins	lipoprotein	NOUN
biomedich-167	235	5	in	in	ADP
biomedich-167	235	6	malaria	malaria	NOUN
biomedich-167	235	7	a	a	DET
biomedich-167	235	8	systematic	systematic	ADJ
biomedich-167	235	9	review	review	NOUN
biomedich-167	235	10	and	and	CCONJ
biomedich-167	235	11	meta	meta	ADJ
biomedich-167	235	12	-	-	PUNCT
biomedich-167	235	13	analysis	analysis	NOUN
biomedich-167	235	14	.	.	PUNCT
biomedich-167	236	1	malaria	malaria	NOUN
biomedich-167	236	2	journal	journal	PROPN
biomedich-167	236	3	.	.	PUNCT
biomedich-167	237	1	12	12	NUM
biomedich-167	237	2	,	,	PUNCT
biomedich-167	237	3	442	442	NUM
biomedich-167	237	4	,	,	PUNCT
biomedich-167	237	5	1	1	NUM
biomedich-167	237	6	-	-	SYM
biomedich-167	237	7	16	16	NUM
biomedich-167	237	8	white	white	PROPN
biomedich-167	237	9	nj	nj	PROPN
biomedich-167	237	10	,	,	PUNCT
biomedich-167	237	11	&	&	CCONJ
biomedich-167	237	12	olliaro	olliaro	VERB
biomedich-167	237	13	pl	pl	PROPN
biomedich-167	237	14	,	,	PUNCT
biomedich-167	237	15	(	(	PUNCT
biomedich-167	237	16	1996	1996	NUM
biomedich-167	237	17	)	)	PUNCT
biomedich-167	237	18	.	.	PUNCT
biomedich-167	238	1	strategies	strategy	NOUN
biomedich-167	238	2	for	for	ADP
biomedich-167	238	3	the	the	DET
biomedich-167	238	4	prevention	prevention	NOUN
biomedich-167	238	5	of	of	ADP
biomedich-167	238	6	antimalarial	antimalarial	ADJ
biomedich-167	238	7	drug	drug	NOUN
biomedich-167	238	8	resistance	resistance	NOUN
biomedich-167	238	9	:	:	PUNCT
biomedich-167	238	10	rationale	rationale	NOUN
biomedich-167	238	11	for	for	ADP
biomedich-167	238	12	combination	combination	NOUN
biomedich-167	238	13	chemotherapy	chemotherapy	NOUN
biomedich-167	238	14	for	for	ADP
biomedich-167	238	15	malaria	malaria	NOUN
biomedich-167	238	16	.	.	PUNCT
biomedich-167	239	1	parasitology	parasitology	NOUN
biomedich-167	239	2	today	today	NOUN
biomedich-167	239	3	12	12	NUM
biomedich-167	239	4	:	:	PUNCT
biomedich-167	239	5	399–401	399–401	NUM
biomedich-167	239	6	world	world	NOUN
biomedich-167	239	7	health	health	NOUN
biomedich-167	239	8	organization	organization	NOUN
biomedich-167	239	9	.	.	PUNCT
biomedich-167	240	1	2005	2005	NUM
biomedich-167	240	2	.	.	PUNCT
biomedich-167	241	1	international	international	ADJ
biomedich-167	241	2	travel	travel	NOUN
biomedich-167	241	3	and	and	CCONJ
biomedich-167	241	4	health	health	NOUN
biomedich-167	241	5	,	,	PUNCT
biomedich-167	241	6	p.	p.	NOUN
biomedich-167	241	7	132	132	NUM
biomedich-167	241	8	–	–	PUNCT
biomedich-167	241	9	151	151	NUM
biomedich-167	241	10	.	.	PUNCT
biomedich-167	242	1	world	world	PROPN
biomedich-167	242	2	health	health	PROPN
biomedich-167	242	3	organization	organization	PROPN
biomedich-167	242	4	,	,	PUNCT
biomedich-167	242	5	geneva	geneva	PROPN
biomedich-167	242	6	,	,	PUNCT
biomedich-167	242	7	switzerland	switzerland	PROPN
biomedich-167	242	8	world	world	PROPN
biomedich-167	242	9	health	health	PROPN
biomedich-167	242	10	organization	organization	PROPN
biomedich-167	242	11	.	.	PUNCT
biomedich-167	243	1	2001	2001	NUM
biomedich-167	243	2	.	.	PUNCT
biomedich-167	244	1	drug	drug	NOUN
biomedich-167	244	2	resistance	resistance	NOUN
biomedich-167	244	3	in	in	ADP
biomedich-167	244	4	malaria	malaria	NOUN
biomedich-167	244	5	yeung	yeung	PROPN
biomedich-167	244	6	s	s	PROPN
biomedich-167	244	7	,	,	PUNCT
biomedich-167	244	8	pongtavornpinyo	pongtavornpinyo	PROPN
biomedich-167	244	9	w	w	PROPN
biomedich-167	244	10	,	,	PUNCT
biomedich-167	244	11	hastings	hastings	PROPN
biomedich-167	244	12	i	i	PRON
biomedich-167	244	13	m	m	PROPN
biomedich-167	244	14	,	,	PUNCT
biomedich-167	244	15	mills	mills	PROPN
biomedich-167	244	16	aj	aj	PROPN
biomedich-167	244	17	,	,	PUNCT
biomedich-167	244	18	&	&	CCONJ
biomedich-167	244	19	white	white	PROPN
biomedich-167	244	20	nj	nj	PROPN
biomedich-167	244	21	.	.	PUNCT
biomedich-167	245	1	(	(	PUNCT
biomedich-167	245	2	2004	2004	NUM
biomedich-167	245	3	)	)	PUNCT
biomedich-167	245	4	.	.	PUNCT
biomedich-167	246	1	antimalarial	antimalarial	ADJ
biomedich-167	246	2	drug	drug	NOUN
biomedich-167	246	3	resistance	resistance	NOUN
biomedich-167	246	4	,	,	PUNCT
biomedich-167	246	5	artemisinin	artemisinin	NOUN
biomedich-167	246	6	based	base	VERB
biomedich-167	246	7	combination	combination	NOUN
biomedich-167	246	8	therapy	therapy	NOUN
biomedich-167	246	9	,	,	PUNCT
biomedich-167	246	10	and	and	CCONJ
biomedich-167	246	11	the	the	DET
biomedich-167	246	12	contribution	contribution	NOUN
biomedich-167	246	13	of	of	ADP
biomedich-167	246	14	modelling	modelling	NOUN
biomedich-167	246	15	to	to	ADP
biomedich-167	246	16	elucidating	elucidate	VERB
biomedich-167	246	17	policy	policy	NOUN
biomedich-167	246	18	choices	choice	NOUN
biomedich-167	246	19	.	.	PUNCT
biomedich-167	247	1	american	american	ADJ
biomedich-167	247	2	journal	journal	PROPN
biomedich-167	247	3	of	of	ADP
biomedich-167	247	4	tropical	tropical	ADJ
biomedich-167	247	5	medicine	medicine	NOUN
biomedich-167	247	6	and	and	CCONJ
biomedich-167	247	7	hygiene	hygiene	NOUN
biomedich-167	247	8	.	.	PUNCT
biomedich-167	248	1	71(2	71(2	NUM
biomedich-167	248	2	):	):	PUNCT
biomedich-167	248	3	179	179	NUM
biomedich-167	248	4	-	-	SYM
biomedich-167	248	5	86	86	NUM