id	sid	tid	token	lemma	pos
biomedich-176	1	1	biology	biology	NOUN
biomedich-176	1	2	,	,	PUNCT
biomedich-176	1	3	medicine	medicine	NOUN
biomedich-176	1	4	,	,	PUNCT
biomedich-176	1	5	&	&	CCONJ
biomedich-176	1	6	natural	natural	ADJ
biomedich-176	1	7	product	product	NOUN
biomedich-176	1	8	chemistry	chemistry	NOUN
biomedich-176	1	9	issn	issn	VERB
biomedich-176	1	10	2089	2089	NUM
biomedich-176	1	11	-	-	SYM
biomedich-176	1	12	6514	6514	NUM
biomedich-176	1	13	(	(	PUNCT
biomedich-176	1	14	paper	paper	NOUN
biomedich-176	1	15	)	)	PUNCT
biomedich-176	1	16	volume	volume	NOUN
biomedich-176	1	17	11	11	NUM
biomedich-176	1	18	,	,	PUNCT
biomedich-176	1	19	number	number	NOUN
biomedich-176	1	20	1	1	NUM
biomedich-176	1	21	,	,	PUNCT
biomedich-176	1	22	april	april	PROPN
biomedich-176	1	23	2022	2022	NUM
biomedich-176	2	1	|	|	ADV
biomedich-176	2	2	pages	page	NOUN
biomedich-176	2	3	:	:	PUNCT
biomedich-176	2	4	45	45	NUM
biomedich-176	2	5	-	-	SYM
biomedich-176	2	6	54	54	NUM
biomedich-176	2	7	|	|	ADV
biomedich-176	2	8	doi	doi	NOUN
biomedich-176	2	9	:	:	PUNCT
biomedich-176	2	10	10.14421	10.14421	NUM
biomedich-176	2	11	/	/	SYM
biomedich-176	2	12	biomedich.2022.111.45	biomedich.2022.111.45	NOUN
biomedich-176	2	13	-	-	PUNCT
biomedich-176	2	14	54	54	NUM
biomedich-176	2	15	issn	issn	PROPN
biomedich-176	2	16	2540	2540	NUM
biomedich-176	2	17	-	-	SYM
biomedich-176	2	18	9328	9328	NUM
biomedich-176	2	19	(	(	PUNCT
biomedich-176	2	20	online	online	ADV
biomedich-176	2	21	)	)	PUNCT
biomedich-176	2	22	the	the	DET
biomedich-176	2	23	roles	role	NOUN
biomedich-176	2	24	of	of	ADP
biomedich-176	2	25	the	the	DET
biomedich-176	2	26	fluorescent	fluorescent	NOUN
biomedich-176	2	27	in	in	ADP
biomedich-176	2	28	situ	situ	ADJ
biomedich-176	2	29	hybridization	hybridization	NOUN
biomedich-176	2	30	(	(	PUNCT
biomedich-176	2	31	fish	fish	NOUN
biomedich-176	2	32	)	)	PUNCT
biomedich-176	2	33	and	and	CCONJ
biomedich-176	2	34	comparative	comparative	ADJ
biomedich-176	2	35	genomic	genomic	NOUN
biomedich-176	2	36	hybridization	hybridization	NOUN
biomedich-176	2	37	(	(	PUNCT
biomedich-176	2	38	cgh	cgh	PROPN
biomedich-176	2	39	)	)	PUNCT
biomedich-176	2	40	techniques	technique	NOUN
biomedich-176	2	41	in	in	ADP
biomedich-176	2	42	the	the	DET
biomedich-176	2	43	detection	detection	NOUN
biomedich-176	2	44	of	of	ADP
biomedich-176	2	45	the	the	DET
biomedich-176	2	46	breast	breast	NOUN
biomedich-176	2	47	cancer	cancer	NOUN
biomedich-176	2	48	harem	harem	PROPN
biomedich-176	2	49	othman	othman	PROPN
biomedich-176	2	50	smail	smail	PROPN
biomedich-176	2	51	department	department	PROPN
biomedich-176	2	52	of	of	ADP
biomedich-176	2	53	biology	biology	NOUN
biomedich-176	2	54	,	,	PUNCT
biomedich-176	2	55	faculty	faculty	NOUN
biomedich-176	2	56	of	of	ADP
biomedich-176	2	57	science	science	NOUN
biomedich-176	2	58	and	and	CCONJ
biomedich-176	2	59	health	health	NOUN
biomedich-176	2	60	,	,	PUNCT
biomedich-176	2	61	koya	koya	PROPN
biomedich-176	2	62	university	university	PROPN
biomedich-176	2	63	,	,	PUNCT
biomedich-176	2	64	koya	koya	PROPN
biomedich-176	2	65	koy45	koy45	PROPN
biomedich-176	2	66	,	,	PUNCT
biomedich-176	2	67	kurdistan	kurdistan	PROPN
biomedich-176	2	68	region	region	NOUN
biomedich-176	2	69	-	-	PUNCT
biomedich-176	2	70	f.r	f.r	PROPN
biomedich-176	2	71	.	.	PUNCT
biomedich-176	2	72	iraq	iraq	PROPN
biomedich-176	2	73	.	.	PUNCT
biomedich-176	3	1	corresponding	correspond	VERB
biomedich-176	3	2	author	author	NOUN
biomedich-176	3	3	harem.othman@koyauniversity.org	harem.othman@koyauniversity.org	PROPN
biomedich-176	3	4	manuscript	manuscript	NOUN
biomedich-176	3	5	received	receive	VERB
biomedich-176	3	6	:	:	PUNCT
biomedich-176	3	7	25	25	NUM
biomedich-176	3	8	february	february	PROPN
biomedich-176	3	9	,	,	PUNCT
biomedich-176	3	10	2022	2022	NUM
biomedich-176	3	11	.	.	PUNCT
biomedich-176	4	1	revision	revision	NOUN
biomedich-176	4	2	accepted	accept	VERB
biomedich-176	4	3	:	:	PUNCT
biomedich-176	4	4	11	11	NUM
biomedich-176	4	5	march	march	NOUN
biomedich-176	4	6	,	,	PUNCT
biomedich-176	4	7	2022	2022	NUM
biomedich-176	4	8	.	.	PUNCT
biomedich-176	5	1	published	publish	VERB
biomedich-176	5	2	:	:	PUNCT
biomedich-176	5	3	24	24	NUM
biomedich-176	5	4	march	march	NOUN
biomedich-176	5	5	,	,	PUNCT
biomedich-176	5	6	2022	2022	NUM
biomedich-176	5	7	.	.	PUNCT
biomedich-176	6	1	abstract	abstract	ADJ
biomedich-176	6	2	this	this	DET
biomedich-176	6	3	paper	paper	NOUN
biomedich-176	6	4	aimed	aim	VERB
biomedich-176	6	5	to	to	PART
biomedich-176	6	6	understand	understand	VERB
biomedich-176	6	7	and	and	CCONJ
biomedich-176	6	8	compare	compare	VERB
biomedich-176	6	9	the	the	DET
biomedich-176	6	10	two	two	NUM
biomedich-176	6	11	popular	popular	ADJ
biomedich-176	6	12	cytogenetic	cytogenetic	ADJ
biomedich-176	6	13	techniques	technique	NOUN
biomedich-176	6	14	of	of	ADP
biomedich-176	6	15	fluorescence	fluorescence	NOUN
biomedich-176	6	16	in	in	ADP
biomedich-176	6	17	situ	situ	ADJ
biomedich-176	6	18	hybridization	hybridization	NOUN
biomedich-176	6	19	(	(	PUNCT
biomedich-176	6	20	fish	fish	NOUN
biomedich-176	6	21	)	)	PUNCT
biomedich-176	6	22	and	and	CCONJ
biomedich-176	6	23	comparative	comparative	ADJ
biomedich-176	6	24	genomic	genomic	NOUN
biomedich-176	6	25	hybridization	hybridization	NOUN
biomedich-176	6	26	(	(	PUNCT
biomedich-176	6	27	cgh	cgh	PROPN
biomedich-176	6	28	)	)	PUNCT
biomedich-176	6	29	in	in	ADP
biomedich-176	6	30	detecting	detect	VERB
biomedich-176	6	31	breast	breast	NOUN
biomedich-176	6	32	cancer	cancer	NOUN
biomedich-176	6	33	chromosomal	chromosomal	ADJ
biomedich-176	6	34	abnormality	abnormality	NOUN
biomedich-176	6	35	.	.	PUNCT
biomedich-176	7	1	several	several	ADJ
biomedich-176	7	2	chromosomal	chromosomal	ADJ
biomedich-176	7	3	anomalies	anomaly	NOUN
biomedich-176	7	4	play	play	VERB
biomedich-176	7	5	a	a	DET
biomedich-176	7	6	role	role	NOUN
biomedich-176	7	7	in	in	ADP
biomedich-176	7	8	the	the	DET
biomedich-176	7	9	development	development	NOUN
biomedich-176	7	10	of	of	ADP
biomedich-176	7	11	breast	breast	NOUN
biomedich-176	7	12	cancer	cancer	NOUN
biomedich-176	7	13	,	,	PUNCT
biomedich-176	7	14	and	and	CCONJ
biomedich-176	7	15	the	the	DET
biomedich-176	7	16	two	two	NUM
biomedich-176	7	17	above	above	ADP
biomedich-176	7	18	approaches	approach	NOUN
biomedich-176	7	19	play	play	VERB
biomedich-176	7	20	an	an	DET
biomedich-176	7	21	important	important	ADJ
biomedich-176	7	22	role	role	NOUN
biomedich-176	7	23	in	in	ADP
biomedich-176	7	24	confirming	confirm	VERB
biomedich-176	7	25	fluorescence	fluorescence	NOUN
biomedich-176	7	26	in	in	ADP
biomedich-176	7	27	situ	situ	ADJ
biomedich-176	7	28	hybridization	hybridization	NOUN
biomedich-176	7	29	in	in	ADP
biomedich-176	7	30	particular	particular	ADJ
biomedich-176	7	31	(	(	PUNCT
biomedich-176	7	32	fish	fish	NOUN
biomedich-176	7	33	)	)	PUNCT
biomedich-176	7	34	.	.	PUNCT
biomedich-176	8	1	however	however	ADV
biomedich-176	8	2	,	,	PUNCT
biomedich-176	8	3	comparative	comparative	ADJ
biomedich-176	8	4	genomic	genomic	NOUN
biomedich-176	8	5	hybridization	hybridization	NOUN
biomedich-176	8	6	has	have	AUX
biomedich-176	8	7	developed	develop	VERB
biomedich-176	8	8	dna	dna	PROPN
biomedich-176	8	9	copy	copy	VERB
biomedich-176	8	10	number	number	NOUN
biomedich-176	8	11	profiles	profile	NOUN
biomedich-176	8	12	for	for	ADP
biomedich-176	8	13	most	most	ADJ
biomedich-176	8	14	of	of	ADP
biomedich-176	8	15	the	the	DET
biomedich-176	8	16	publicly	publicly	ADV
biomedich-176	8	17	available	available	ADJ
biomedich-176	8	18	breast	breast	NOUN
biomedich-176	8	19	cancer	cancer	NOUN
biomedich-176	8	20	cell	cell	NOUN
biomedich-176	8	21	lines	line	NOUN
biomedich-176	8	22	for	for	ADP
biomedich-176	8	23	the	the	DET
biomedich-176	8	24	fish	fish	NOUN
biomedich-176	8	25	methods	method	NOUN
biomedich-176	8	26	rely	rely	VERB
biomedich-176	8	27	on	on	ADP
biomedich-176	8	28	the	the	DET
biomedich-176	8	29	fluorescent	fluorescent	ADJ
biomedich-176	8	30	probes	probe	NOUN
biomedich-176	8	31	.	.	PUNCT
biomedich-176	9	1	chromosomal	chromosomal	ADJ
biomedich-176	9	2	profiles	profile	NOUN
biomedich-176	9	3	can	can	AUX
biomedich-176	9	4	be	be	AUX
biomedich-176	9	5	generated	generate	VERB
biomedich-176	9	6	for	for	ADP
biomedich-176	9	7	the	the	DET
biomedich-176	9	8	suspected	suspect	VERB
biomedich-176	9	9	chromosomal	chromosomal	ADJ
biomedich-176	9	10	abnormality	abnormality	NOUN
biomedich-176	9	11	,	,	PUNCT
biomedich-176	9	12	copy	copy	VERB
biomedich-176	9	13	number	number	NOUN
biomedich-176	9	14	changes	change	NOUN
biomedich-176	9	15	between	between	ADP
biomedich-176	9	16	the	the	DET
biomedich-176	9	17	tumour	tumour	NOUN
biomedich-176	9	18	and	and	CCONJ
biomedich-176	9	19	the	the	DET
biomedich-176	9	20	dna	dna	PROPN
biomedich-176	9	21	control	control	NOUN
biomedich-176	9	22	can	can	AUX
biomedich-176	9	23	be	be	AUX
biomedich-176	9	24	compared	compare	VERB
biomedich-176	9	25	,	,	PUNCT
biomedich-176	9	26	and	and	CCONJ
biomedich-176	9	27	the	the	DET
biomedich-176	9	28	results	result	NOUN
biomedich-176	9	29	can	can	AUX
biomedich-176	9	30	be	be	AUX
biomedich-176	9	31	registered	register	VERB
biomedich-176	9	32	.	.	PUNCT
biomedich-176	10	1	today	today	NOUN
biomedich-176	10	2	,	,	PUNCT
biomedich-176	10	3	modern	modern	ADJ
biomedich-176	10	4	cytogenetic	cytogenetic	ADJ
biomedich-176	10	5	tools	tool	NOUN
biomedich-176	10	6	such	such	ADJ
biomedich-176	10	7	as	as	ADP
biomedich-176	10	8	fluorescence	fluorescence	NOUN
biomedich-176	10	9	in	in	ADP
biomedich-176	10	10	situ	situ	ADJ
biomedich-176	10	11	hybridization	hybridization	NOUN
biomedich-176	10	12	(	(	PUNCT
biomedich-176	10	13	fish	fish	NOUN
biomedich-176	10	14	)	)	PUNCT
biomedich-176	10	15	are	be	AUX
biomedich-176	10	16	more	more	ADV
biomedich-176	10	17	commonly	commonly	ADV
biomedich-176	10	18	used	use	VERB
biomedich-176	10	19	to	to	PART
biomedich-176	10	20	detect	detect	VERB
biomedich-176	10	21	any	any	DET
biomedich-176	10	22	microdeletion	microdeletion	NOUN
biomedich-176	10	23	that	that	PRON
biomedich-176	10	24	can	can	AUX
biomedich-176	10	25	not	not	PART
biomedich-176	10	26	be	be	AUX
biomedich-176	10	27	detected	detect	VERB
biomedich-176	10	28	by	by	ADP
biomedich-176	10	29	conventional	conventional	ADJ
biomedich-176	10	30	cytogenetic	cytogenetic	ADJ
biomedich-176	10	31	karyotypes	karyotype	NOUN
biomedich-176	10	32	that	that	PRON
biomedich-176	10	33	involve	involve	VERB
biomedich-176	10	34	a	a	DET
biomedich-176	10	35	high	high	ADJ
biomedich-176	10	36	rate	rate	NOUN
biomedich-176	10	37	of	of	ADP
biomedich-176	10	38	cell	cell	NOUN
biomedich-176	10	39	division	division	NOUN
biomedich-176	10	40	and	and	CCONJ
biomedich-176	10	41	good	good	ADJ
biomedich-176	10	42	chromosomal	chromosomal	ADJ
biomedich-176	10	43	morphology	morphology	NOUN
biomedich-176	10	44	,	,	PUNCT
biomedich-176	10	45	which	which	PRON
biomedich-176	10	46	pose	pose	VERB
biomedich-176	10	47	challenges	challenge	NOUN
biomedich-176	10	48	for	for	ADP
biomedich-176	10	49	cytogeneticists	cytogeneticist	NOUN
biomedich-176	10	50	,	,	PUNCT
biomedich-176	10	51	and	and	CCONJ
biomedich-176	10	52	a	a	DET
biomedich-176	10	53	long	long	ADJ
biomedich-176	10	54	period	period	NOUN
biomedich-176	10	55	of	of	ADP
biomedich-176	10	56	testing	testing	NOUN
biomedich-176	10	57	and	and	CCONJ
biomedich-176	10	58	research	research	NOUN
biomedich-176	10	59	.	.	PUNCT
biomedich-176	11	1	usually	usually	ADV
biomedich-176	11	2	,	,	PUNCT
biomedich-176	11	3	this	this	PRON
biomedich-176	11	4	is	be	AUX
biomedich-176	11	5	a	a	DET
biomedich-176	11	6	problem	problem	NOUN
biomedich-176	11	7	for	for	ADP
biomedich-176	11	8	physicians	physician	NOUN
biomedich-176	11	9	,	,	PUNCT
biomedich-176	11	10	and	and	CCONJ
biomedich-176	11	11	there	there	PRON
biomedich-176	11	12	are	be	VERB
biomedich-176	11	13	still	still	ADV
biomedich-176	11	14	many	many	ADJ
biomedich-176	11	15	drawbacks	drawback	NOUN
biomedich-176	11	16	and	and	CCONJ
biomedich-176	11	17	disadvantages	disadvantage	NOUN
biomedich-176	11	18	concerning	concern	VERB
biomedich-176	11	19	the	the	DET
biomedich-176	11	20	high	high	ADJ
biomedich-176	11	21	benefits	benefit	NOUN
biomedich-176	11	22	,	,	PUNCT
biomedich-176	11	23	such	such	ADJ
biomedich-176	11	24	as	as	ADP
biomedich-176	11	25	false	false	ADJ
biomedich-176	11	26	findings	finding	NOUN
biomedich-176	11	27	.	.	PUNCT
biomedich-176	12	1	normal	normal	ADJ
biomedich-176	12	2	chromosome	chromosome	NOUN
biomedich-176	12	3	in	in	ADP
biomedich-176	12	4	situ	situ	ADJ
biomedich-176	12	5	hybridization	hybridization	NOUN
biomedich-176	12	6	requires	require	VERB
biomedich-176	12	7	the	the	DET
biomedich-176	12	8	hybridization	hybridization	NOUN
biomedich-176	12	9	of	of	ADP
biomedich-176	12	10	a	a	DET
biomedich-176	12	11	labelled	label	VERB
biomedich-176	12	12	dna	dna	NOUN
biomedich-176	12	13	probe	probe	NOUN
biomedich-176	12	14	into	into	ADP
biomedich-176	12	15	denatured	denature	VERB
biomedich-176	12	16	chromosomal	chromosomal	ADJ
biomedich-176	12	17	dna	dna	NOUN
biomedich-176	12	18	present	present	ADJ
biomedich-176	12	19	in	in	ADP
biomedich-176	12	20	metaphase	metaphase	ADJ
biomedich-176	12	21	chromosomes	chromosome	NOUN
biomedich-176	12	22	in	in	ADP
biomedich-176	12	23	an	an	DET
biomedich-176	12	24	air	air	NOUN
biomedich-176	12	25	-	-	PUNCT
biomedich-176	12	26	dried	dry	VERB
biomedich-176	12	27	microscope	microscope	NOUN
biomedich-176	12	28	slide	slide	NOUN
biomedich-176	12	29	preparation	preparation	NOUN
biomedich-176	12	30	.	.	PUNCT
biomedich-176	13	1	metaphase	metaphase	NOUN
biomedich-176	13	2	spreads	spread	NOUN
biomedich-176	13	3	are	be	AUX
biomedich-176	13	4	used	use	VERB
biomedich-176	13	5	for	for	ADP
biomedich-176	13	6	traditional	traditional	ADJ
biomedich-176	13	7	chromosome	chromosome	NOUN
biomedich-176	13	8	fish	fish	NOUN
biomedich-176	13	9	(	(	PUNCT
biomedich-176	13	10	metaphase	metaphase	NOUN
biomedich-176	13	11	fish	fish	NOUN
biomedich-176	13	12	)	)	PUNCT
biomedich-176	13	13	.	.	PUNCT
biomedich-176	14	1	positive	positive	ADJ
biomedich-176	14	2	and	and	CCONJ
biomedich-176	14	3	positive	positive	ADJ
biomedich-176	14	4	signs	sign	NOUN
biomedich-176	14	5	of	of	ADP
biomedich-176	14	6	hybridization	hybridization	NOUN
biomedich-176	14	7	also	also	ADV
biomedich-176	14	8	appear	appear	VERB
biomedich-176	14	9	as	as	ADP
biomedich-176	14	10	a	a	DET
biomedich-176	14	11	double	double	ADJ
biomedich-176	14	12	spot	spot	NOUN
biomedich-176	14	13	,	,	PUNCT
biomedich-176	14	14	corresponding	correspond	VERB
biomedich-176	14	15	to	to	ADP
biomedich-176	14	16	the	the	DET
biomedich-176	14	17	hybridized	hybridize	VERB
biomedich-176	14	18	probe	probe	NOUN
biomedich-176	14	19	for	for	ADP
biomedich-176	14	20	both	both	DET
biomedich-176	14	21	sister	sister	NOUN
biomedich-176	14	22	chromatids	chromatids	PROPN
biomedich-176	14	23	.	.	PUNCT
biomedich-176	15	1	a	a	DET
biomedich-176	15	2	further	further	ADJ
biomedich-176	15	3	extension	extension	NOUN
biomedich-176	15	4	of	of	ADP
biomedich-176	15	5	chromosome	chromosome	NOUN
biomedich-176	15	6	painting	painting	NOUN
biomedich-176	15	7	is	be	AUX
biomedich-176	15	8	comparative	comparative	ADJ
biomedich-176	15	9	genomic	genomic	NOUN
biomedich-176	15	10	hybridization	hybridization	NOUN
biomedich-176	15	11	(	(	PUNCT
biomedich-176	15	12	cci	cci	PROPN
biomedich-176	15	13	-	-	PUNCT
biomedich-176	15	14	i	i	PROPN
biomedich-176	15	15	)	)	PUNCT
biomedich-176	15	16	.	.	PUNCT
biomedich-176	16	1	cch	cch	PROPN
biomedich-176	16	2	involves	involve	VERB
biomedich-176	16	3	simultaneous	simultaneous	ADJ
biomedich-176	16	4	chromosome	chromosome	NOUN
biomedich-176	16	5	painting	painting	NOUN
biomedich-176	16	6	in	in	ADP
biomedich-176	16	7	two	two	NUM
biomedich-176	16	8	different	different	ADJ
biomedich-176	16	9	colours	colour	NOUN
biomedich-176	16	10	using	use	VERB
biomedich-176	16	11	complete	complete	ADJ
biomedich-176	16	12	dna	dna	NOUN
biomedich-176	16	13	from	from	ADP
biomedich-176	16	14	two	two	NUM
biomedich-176	16	15	similar	similar	ADJ
biomedich-176	16	16	sources	source	NOUN
biomedich-176	16	17	as	as	ADP
biomedich-176	16	18	probes	probe	NOUN
biomedich-176	16	19	,	,	PUNCT
biomedich-176	16	20	which	which	PRON
biomedich-176	16	21	reveal	reveal	VERB
biomedich-176	16	22	variations	variation	NOUN
biomedich-176	16	23	concerning	concern	VERB
biomedich-176	16	24	the	the	DET
biomedich-176	16	25	benefit	benefit	NOUN
biomedich-176	16	26	or	or	CCONJ
biomedich-176	16	27	loss	loss	NOUN
biomedich-176	16	28	of	of	ADP
biomedich-176	16	29	sub	sub	ADJ
biomedich-176	16	30	-	-	ADJ
biomedich-176	16	31	chromosomal	chromosomal	ADJ
biomedich-176	16	32	regions	region	NOUN
biomedich-176	16	33	or	or	CCONJ
biomedich-176	16	34	even	even	ADV
biomedich-176	16	35	entire	entire	ADJ
biomedich-176	16	36	chromosomes	chromosome	NOUN
biomedich-176	16	37	.	.	PUNCT
biomedich-176	17	1	keywords	keyword	NOUN
biomedich-176	17	2	:	:	PUNCT
biomedich-176	17	3	fish	fish	NOUN
biomedich-176	17	4	;	;	PUNCT
biomedich-176	17	5	cgh	cgh	PROPN
biomedich-176	17	6	;	;	PUNCT
biomedich-176	17	7	probe	probe	NOUN
biomedich-176	17	8	;	;	PUNCT
biomedich-176	17	9	classical	classical	ADJ
biomedich-176	17	10	cytogenetic	cytogenetic	NOUN
biomedich-176	17	11	;	;	PUNCT
biomedich-176	17	12	chromosomal	chromosomal	ADJ
biomedich-176	17	13	regions	region	NOUN
biomedich-176	17	14	and	and	CCONJ
biomedich-176	17	15	hybridization	hybridization	NOUN
biomedich-176	17	16	.	.	PUNCT
biomedich-176	18	1	introduction	introduction	NOUN
biomedich-176	18	2	in	in	ADP
biomedich-176	18	3	terms	term	NOUN
biomedich-176	18	4	of	of	ADP
biomedich-176	18	5	histology	histology	NOUN
biomedich-176	18	6	,	,	PUNCT
biomedich-176	18	7	clinical	clinical	ADJ
biomedich-176	18	8	response	response	NOUN
biomedich-176	18	9	,	,	PUNCT
biomedich-176	18	10	diffusion	diffusion	NOUN
biomedich-176	18	11	trends	trend	NOUN
biomedich-176	18	12	to	to	ADP
biomedich-176	18	13	distant	distant	ADJ
biomedich-176	18	14	locations	location	NOUN
biomedich-176	18	15	,	,	PUNCT
biomedich-176	18	16	and	and	CCONJ
biomedich-176	18	17	patient	patient	ADJ
biomedich-176	18	18	outcomes	outcome	NOUN
biomedich-176	18	19	,	,	PUNCT
biomedich-176	18	20	breast	breast	NOUN
biomedich-176	18	21	cancer	cancer	NOUN
biomedich-176	18	22	is	be	AUX
biomedich-176	18	23	heterogeneous	heterogeneous	ADJ
biomedich-176	18	24	(	(	PUNCT
biomedich-176	18	25	prat	prat	NOUN
biomedich-176	18	26	et	et	PROPN
biomedich-176	18	27	al	al	PROPN
biomedich-176	18	28	.	.	PROPN
biomedich-176	18	29	,	,	PUNCT
biomedich-176	18	30	2011	2011	NUM
biomedich-176	18	31	)	)	PUNCT
biomedich-176	18	32	.	.	PUNCT
biomedich-176	19	1	nevertheless	nevertheless	ADV
biomedich-176	19	2	,	,	PUNCT
biomedich-176	19	3	the	the	DET
biomedich-176	19	4	most	most	ADV
biomedich-176	19	5	common	common	ADJ
biomedich-176	19	6	cause	cause	NOUN
biomedich-176	19	7	of	of	ADP
biomedich-176	19	8	death	death	NOUN
biomedich-176	19	9	from	from	ADP
biomedich-176	19	10	cancer	cancer	NOUN
biomedich-176	19	11	worldwide	worldwide	ADV
biomedich-176	19	12	is	be	AUX
biomedich-176	19	13	breast	breast	NOUN
biomedich-176	19	14	cancer	cancer	NOUN
biomedich-176	19	15	.	.	PUNCT
biomedich-176	20	1	rates	rate	NOUN
biomedich-176	20	2	differ	differ	VERB
biomedich-176	20	3	about	about	ADV
biomedich-176	20	4	five	five	NUM
biomedich-176	20	5	-	-	NOUN
biomedich-176	20	6	fold	fold	NOUN
biomedich-176	20	7	across	across	ADP
biomedich-176	20	8	the	the	DET
biomedich-176	20	9	world	world	NOUN
biomedich-176	20	10	,	,	PUNCT
biomedich-176	20	11	but	but	CCONJ
biomedich-176	20	12	they	they	PRON
biomedich-176	20	13	are	be	AUX
biomedich-176	20	14	growing	grow	VERB
biomedich-176	20	15	in	in	ADP
biomedich-176	20	16	regions	region	NOUN
biomedich-176	20	17	with	with	ADP
biomedich-176	20	18	low	low	ADJ
biomedich-176	20	19	disease	disease	NOUN
biomedich-176	20	20	rates	rate	NOUN
biomedich-176	20	21	until	until	ADP
biomedich-176	20	22	recently	recently	ADV
biomedich-176	20	23	(	(	PUNCT
biomedich-176	20	24	key	key	PROPN
biomedich-176	20	25	et	et	PROPN
biomedich-176	20	26	al	al	PROPN
biomedich-176	20	27	.	.	PROPN
biomedich-176	20	28	,	,	PUNCT
biomedich-176	20	29	2011	2011	NUM
biomedich-176	20	30	)	)	PUNCT
biomedich-176	20	31	.	.	PUNCT
biomedich-176	21	1	furthermore	furthermore	ADV
biomedich-176	21	2	,	,	PUNCT
biomedich-176	21	3	the	the	DET
biomedich-176	21	4	availability	availability	NOUN
biomedich-176	21	5	of	of	ADP
biomedich-176	21	6	cytogenetics	cytogenetic	NOUN
biomedich-176	21	7	and	and	CCONJ
biomedich-176	21	8	cytogenetics	cytogenetic	NOUN
biomedich-176	21	9	technologies	technology	NOUN
biomedich-176	21	10	has	have	AUX
biomedich-176	21	11	enhanced	enhance	VERB
biomedich-176	21	12	the	the	DET
biomedich-176	21	13	detection	detection	NOUN
biomedich-176	21	14	and	and	CCONJ
biomedich-176	21	15	recognition	recognition	NOUN
biomedich-176	21	16	of	of	ADP
biomedich-176	21	17	molecular	molecular	ADJ
biomedich-176	21	18	tumour	tumour	NOUN
biomedich-176	21	19	signatures	signature	NOUN
biomedich-176	21	20	and	and	CCONJ
biomedich-176	21	21	the	the	DET
biomedich-176	21	22	understanding	understanding	NOUN
biomedich-176	21	23	of	of	ADP
biomedich-176	21	24	the	the	DET
biomedich-176	21	25	initiation	initiation	NOUN
biomedich-176	21	26	and	and	CCONJ
biomedich-176	21	27	progression	progression	NOUN
biomedich-176	21	28	of	of	ADP
biomedich-176	21	29	cancer	cancer	NOUN
biomedich-176	21	30	(	(	PUNCT
biomedich-176	21	31	ribeiro	ribeiro	PROPN
biomedich-176	21	32	et	et	PROPN
biomedich-176	21	33	al	al	PROPN
biomedich-176	21	34	.	.	PROPN
biomedich-176	21	35	,	,	PUNCT
biomedich-176	21	36	2019	2019	NUM
biomedich-176	21	37	)	)	PUNCT
biomedich-176	21	38	.	.	PUNCT
biomedich-176	22	1	the	the	DET
biomedich-176	22	2	fluorescence	fluorescence	NOUN
biomedich-176	22	3	in	in	ADP
biomedich-176	22	4	situ	situ	ADJ
biomedich-176	22	5	hybridization	hybridization	NOUN
biomedich-176	22	6	(	(	PUNCT
biomedich-176	22	7	fish	fish	NOUN
biomedich-176	22	8	)	)	PUNCT
biomedich-176	22	9	technique	technique	NOUN
biomedich-176	22	10	that	that	PRON
biomedich-176	22	11	plays	play	VERB
biomedich-176	22	12	a	a	DET
biomedich-176	22	13	leading	lead	VERB
biomedich-176	22	14	role	role	NOUN
biomedich-176	22	15	in	in	ADP
biomedich-176	22	16	diagnostic	diagnostic	ADJ
biomedich-176	22	17	pathology	pathology	NOUN
biomedich-176	22	18	has	have	AUX
biomedich-176	22	19	provided	provide	VERB
biomedich-176	22	20	valuable	valuable	ADJ
biomedich-176	22	21	information	information	NOUN
biomedich-176	22	22	on	on	ADP
biomedich-176	22	23	genomic	genomic	ADJ
biomedich-176	22	24	variations	variation	NOUN
biomedich-176	22	25	in	in	ADP
biomedich-176	22	26	malignant	malignant	ADJ
biomedich-176	22	27	cells	cell	NOUN
biomedich-176	22	28	for	for	ADP
biomedich-176	22	29	its	its	PRON
biomedich-176	22	30	single	single	ADJ
biomedich-176	22	31	-	-	PUNCT
biomedich-176	22	32	cell	cell	NOUN
biomedich-176	22	33	study	study	NOUN
biomedich-176	22	34	(	(	PUNCT
biomedich-176	22	35	das	das	PROPN
biomedich-176	22	36	et	et	PROPN
biomedich-176	22	37	al	al	PROPN
biomedich-176	22	38	.	.	PROPN
biomedich-176	22	39	,	,	PUNCT
biomedich-176	22	40	2013	2013	NUM
biomedich-176	22	41	)	)	PUNCT
biomedich-176	22	42	.	.	PUNCT
biomedich-176	23	1	fish	fish	NOUN
biomedich-176	23	2	is	be	AUX
biomedich-176	23	3	a	a	DET
biomedich-176	23	4	molecular	molecular	ADJ
biomedich-176	23	5	tool	tool	NOUN
biomedich-176	23	6	in	in	ADP
biomedich-176	23	7	which	which	PRON
biomedich-176	23	8	both	both	DET
biomedich-176	23	9	metaphase	metaphase	NOUN
biomedich-176	23	10	chromosomes	chromosome	NOUN
biomedich-176	23	11	and	and	CCONJ
biomedich-176	23	12	interphase	interphase	NOUN
biomedich-176	23	13	nuclei	nucleus	NOUN
biomedich-176	23	14	identify	identify	VERB
biomedich-176	23	15	numerical	numerical	ADJ
biomedich-176	23	16	and	and	CCONJ
biomedich-176	23	17	structural	structural	ADJ
biomedich-176	23	18	defects	defect	NOUN
biomedich-176	23	19	.	.	PUNCT
biomedich-176	24	1	fish	fish	NOUN
biomedich-176	24	2	is	be	AUX
biomedich-176	24	3	widely	widely	ADV
biomedich-176	24	4	used	use	VERB
biomedich-176	24	5	to	to	PART
biomedich-176	24	6	identify	identify	VERB
biomedich-176	24	7	translocations	translocation	NOUN
biomedich-176	24	8	and	and	CCONJ
biomedich-176	24	9	determine	determine	VERB
biomedich-176	24	10	gene	gene	NOUN
biomedich-176	24	11	deletion	deletion	NOUN
biomedich-176	24	12	and	and	CCONJ
biomedich-176	24	13	amplification	amplification	NOUN
biomedich-176	24	14	in	in	ADP
biomedich-176	24	15	tumours	tumours	PROPN
biomedich-176	24	16	as	as	ADP
biomedich-176	24	17	a	a	DET
biomedich-176	24	18	prognostic	prognostic	ADJ
biomedich-176	24	19	and	and	CCONJ
biomedich-176	24	20	diagnostic	diagnostic	ADJ
biomedich-176	24	21	method	method	NOUN
biomedich-176	24	22	(	(	PUNCT
biomedich-176	24	23	brown	brown	PROPN
biomedich-176	24	24	et	et	PROPN
biomedich-176	24	25	al	al	PROPN
biomedich-176	24	26	.	.	PROPN
biomedich-176	24	27	,	,	PUNCT
biomedich-176	24	28	2007	2007	NUM
biomedich-176	24	29	)	)	PUNCT
biomedich-176	24	30	.	.	PUNCT
biomedich-176	25	1	the	the	DET
biomedich-176	25	2	technique	technique	NOUN
biomedich-176	25	3	utilizes	utilize	VERB
biomedich-176	25	4	the	the	DET
biomedich-176	25	5	inherent	inherent	ADJ
biomedich-176	25	6	capacity	capacity	NOUN
biomedich-176	25	7	to	to	PART
biomedich-176	25	8	hybridize	hybridize	VERB
biomedich-176	25	9	complementary	complementary	ADJ
biomedich-176	25	10	strands	strand	NOUN
biomedich-176	25	11	of	of	ADP
biomedich-176	25	12	dna	dna	NOUN
biomedich-176	25	13	or	or	CCONJ
biomedich-176	25	14	rna	rna	NOUN
biomedich-176	25	15	from	from	ADP
biomedich-176	25	16	various	various	ADJ
biomedich-176	25	17	sources	source	NOUN
biomedich-176	25	18	.	.	PUNCT
biomedich-176	26	1	the	the	DET
biomedich-176	26	2	theory	theory	NOUN
biomedich-176	26	3	of	of	ADP
biomedich-176	26	4	annealing	anneal	VERB
biomedich-176	26	5	a	a	DET
biomedich-176	26	6	labelled	label	VERB
biomedich-176	26	7	nucleic	nucleic	ADJ
biomedich-176	26	8	acid	acid	NOUN
biomedich-176	26	9	probe	probe	NOUN
biomedich-176	26	10	to	to	PART
biomedich-176	26	11	complementary	complementary	ADJ
biomedich-176	26	12	sequences	sequence	NOUN
biomedich-176	26	13	inside	inside	ADP
biomedich-176	26	14	cells	cell	NOUN
biomedich-176	26	15	or	or	CCONJ
biomedich-176	26	16	tissue	tissue	NOUN
biomedich-176	26	17	mounted	mount	VERB
biomedich-176	26	18	(	(	PUNCT
biomedich-176	26	19	in	in	ADP
biomedich-176	26	20	situ	situ	NOUN
biomedich-176	26	21	)	)	PUNCT
biomedich-176	26	22	on	on	ADP
biomedich-176	26	23	a	a	DET
biomedich-176	26	24	microscope	microscope	NOUN
biomedich-176	26	25	slide	slide	NOUN
biomedich-176	26	26	is	be	AUX
biomedich-176	26	27	based	base	VERB
biomedich-176	26	28	on	on	ADP
biomedich-176	26	29	in	in	ADP
biomedich-176	26	30	situ	situ	ADJ
biomedich-176	26	31	hybridizations	hybridization	NOUN
biomedich-176	26	32	(	(	PUNCT
biomedich-176	26	33	karimi	karimi	PROPN
biomedich-176	26	34	et	et	PROPN
biomedich-176	26	35	al	al	PROPN
biomedich-176	26	36	.	.	PROPN
biomedich-176	26	37	,	,	PUNCT
biomedich-176	26	38	2020	2020	NUM
biomedich-176	26	39	)	)	PUNCT
biomedich-176	26	40	.	.	PUNCT
biomedich-176	27	1	genomic	genomic	ADJ
biomedich-176	27	2	changes	change	NOUN
biomedich-176	27	3	,	,	PUNCT
biomedich-176	27	4	amplifications	amplification	NOUN
biomedich-176	27	5	,	,	PUNCT
biomedich-176	27	6	and	and	CCONJ
biomedich-176	27	7	deletions	deletion	NOUN
biomedich-176	27	8	may	may	AUX
biomedich-176	27	9	reduce	reduce	VERB
biomedich-176	27	10	the	the	DET
biomedich-176	27	11	complexity	complexity	NOUN
biomedich-176	27	12	of	of	ADP
biomedich-176	27	13	genomic	genomic	ADJ
biomedich-176	27	14	data	datum	NOUN
biomedich-176	27	15	observed	observe	VERB
biomedich-176	27	16	by	by	ADP
biomedich-176	27	17	comparative	comparative	ADJ
biomedich-176	27	18	genomic	genomic	NOUN
biomedich-176	27	19	hybridization	hybridization	NOUN
biomedich-176	27	20	(	(	PUNCT
biomedich-176	27	21	przybytkowski	przybytkowski	NOUN
biomedich-176	27	22	et	et	PROPN
biomedich-176	27	23	al	al	PROPN
biomedich-176	27	24	.	.	PROPN
biomedich-176	27	25	,	,	PUNCT
biomedich-176	27	26	2014	2014	NUM
biomedich-176	27	27	)	)	PUNCT
biomedich-176	27	28	.	.	PUNCT
biomedich-176	28	1	by	by	ADP
biomedich-176	28	2	comparing	compare	VERB
biomedich-176	28	3	the	the	DET
biomedich-176	28	4	samples	sample	NOUN
biomedich-176	28	5	with	with	ADP
biomedich-176	28	6	reference	reference	NOUN
biomedich-176	28	7	dna	dna	PROPN
biomedich-176	28	8	,	,	PUNCT
biomedich-176	28	9	cgh	cgh	PROPN
biomedich-176	28	10	detects	detect	NOUN
biomedich-176	28	11	changes	change	NOUN
biomedich-176	28	12	in	in	ADP
biomedich-176	28	13	the	the	DET
biomedich-176	28	14	copy	copy	NOUN
biomedich-176	28	15	number	number	NOUN
biomedich-176	28	16	of	of	ADP
biomedich-176	28	17	individual	individual	ADJ
biomedich-176	28	18	chromosomes	chromosome	NOUN
biomedich-176	28	19	or	or	CCONJ
biomedich-176	28	20	chromosomal	chromosomal	ADJ
biomedich-176	28	21	regions	region	NOUN
biomedich-176	28	22	,	,	PUNCT
biomedich-176	28	23	such	such	ADJ
biomedich-176	28	24	as	as	ADP
biomedich-176	28	25	changes	change	NOUN
biomedich-176	28	26	in	in	ADP
biomedich-176	28	27	relative	relative	ADJ
biomedich-176	28	28	genome	genome	NOUN
biomedich-176	28	29	size	size	NOUN
biomedich-176	28	30	and	and	CCONJ
biomedich-176	28	31	ploidy	ploidy	ADJ
biomedich-176	28	32	levels	level	NOUN
biomedich-176	28	33	in	in	ADP
biomedich-176	28	34	test	test	NOUN
biomedich-176	28	35	samples	sample	NOUN
biomedich-176	28	36	.	.	PUNCT
biomedich-176	29	1	this	this	DET
biomedich-176	29	2	technique	technique	NOUN
biomedich-176	29	3	was	be	AUX
biomedich-176	29	4	initially	initially	ADV
biomedich-176	29	5	designed	design	VERB
biomedich-176	29	6	to	to	PART
biomedich-176	29	7	examine	examine	VERB
biomedich-176	29	8	the	the	DET
biomedich-176	29	9	differences	difference	NOUN
biomedich-176	29	10	between	between	ADP
biomedich-176	29	11	solid	solid	ADJ
biomedich-176	29	12	tumours	tumour	NOUN
biomedich-176	29	13	and	and	CCONJ
biomedich-176	29	14	normal	normal	ADJ
biomedich-176	29	15	tissues	tissue	NOUN
biomedich-176	29	16	in	in	ADP
biomedich-176	29	17	chromosomal	chromosomal	ADJ
biomedich-176	29	18	supplements	supplement	NOUN
biomedich-176	29	19	(	(	PUNCT
biomedich-176	29	20	zhang	zhang	X
biomedich-176	29	21	et	et	PROPN
biomedich-176	29	22	al	al	PROPN
biomedich-176	29	23	.	.	PROPN
biomedich-176	29	24	,	,	PUNCT
biomedich-176	29	25	2015	2015	NUM
biomedich-176	29	26	)	)	PUNCT
biomedich-176	29	27	.	.	PUNCT
biomedich-176	30	1	it	it	PRON
biomedich-176	30	2	is	be	AUX
biomedich-176	30	3	expected	expect	VERB
biomedich-176	30	4	that	that	SCONJ
biomedich-176	30	5	the	the	DET
biomedich-176	30	6	precise	precise	ADJ
biomedich-176	30	7	classification	classification	NOUN
biomedich-176	30	8	of	of	ADP
biomedich-176	30	9	these	these	DET
biomedich-176	30	10	genomic	genomic	ADJ
biomedich-176	30	11	changes	change	NOUN
biomedich-176	30	12	would	would	AUX
biomedich-176	30	13	have	have	VERB
biomedich-176	30	14	an	an	DET
biomedich-176	30	15	important	important	ADJ
biomedich-176	30	16	effect	effect	NOUN
biomedich-176	30	17	https://doi.org/10.14421/biomedich.2022.111.45-54	https://doi.org/10.14421/biomedich.2022.111.45-54	NOUN
biomedich-176	30	18	46	46	NUM
biomedich-176	30	19	biology	biology	NOUN
biomedich-176	30	20	,	,	PUNCT
biomedich-176	30	21	medicine	medicine	NOUN
biomedich-176	30	22	,	,	PUNCT
biomedich-176	30	23	&	&	CCONJ
biomedich-176	30	24	natural	natural	ADJ
biomedich-176	30	25	product	product	NOUN
biomedich-176	30	26	chemistry	chemistry	NOUN
biomedich-176	30	27	11	11	NUM
biomedich-176	30	28	(	(	PUNCT
biomedich-176	30	29	1	1	NUM
biomedich-176	30	30	)	)	PUNCT
biomedich-176	30	31	,	,	PUNCT
biomedich-176	30	32	2022	2022	NUM
biomedich-176	30	33	:	:	PUNCT
biomedich-176	30	34	45	45	NUM
biomedich-176	30	35	-	-	SYM
biomedich-176	30	36	54	54	NUM
biomedich-176	30	37	on	on	ADP
biomedich-176	30	38	translational	translational	ADJ
biomedich-176	30	39	and	and	CCONJ
biomedich-176	30	40	fundamental	fundamental	ADJ
biomedich-176	30	41	research	research	NOUN
biomedich-176	30	42	(	(	PUNCT
biomedich-176	30	43	climen	climan	NOUN
biomedich-176	30	44	et	et	NOUN
biomedich-176	30	45	al	al	PROPN
biomedich-176	30	46	.	.	PROPN
biomedich-176	30	47	,	,	PUNCT
biomedich-176	30	48	2007	2007	NUM
biomedich-176	30	49	)	)	PUNCT
biomedich-176	30	50	.	.	PUNCT
biomedich-176	31	1	for	for	ADP
biomedich-176	31	2	example	example	NOUN
biomedich-176	31	3	,	,	PUNCT
biomedich-176	31	4	comparative	comparative	ADJ
biomedich-176	31	5	genomic	genomic	NOUN
biomedich-176	31	6	hybridization	hybridization	NOUN
biomedich-176	31	7	has	have	AUX
biomedich-176	31	8	been	be	AUX
biomedich-176	31	9	instrumental	instrumental	ADJ
biomedich-176	31	10	in	in	ADP
biomedich-176	31	11	the	the	DET
biomedich-176	31	12	dissection	dissection	NOUN
biomedich-176	31	13	of	of	ADP
biomedich-176	31	14	distinct	distinct	ADJ
biomedich-176	31	15	molecular	molecular	ADJ
biomedich-176	31	16	pathways	pathway	NOUN
biomedich-176	31	17	to	to	ADP
biomedich-176	31	18	malignancy	malignancy	NOUN
biomedich-176	31	19	of	of	ADP
biomedich-176	31	20	the	the	DET
biomedich-176	31	21	breast	breast	NOUN
biomedich-176	31	22	and	and	CCONJ
biomedich-176	31	23	developing	develop	VERB
biomedich-176	31	24	a	a	DET
biomedich-176	31	25	direct	direct	ADJ
biomedich-176	31	26	relationship	relationship	NOUN
biomedich-176	31	27	between	between	ADP
biomedich-176	31	28	genotype	genotype	NOUN
biomedich-176	31	29	and	and	CCONJ
biomedich-176	31	30	clinical	clinical	ADJ
biomedich-176	31	31	pathology	pathology	NOUN
biomedich-176	31	32	(	(	PUNCT
biomedich-176	31	33	reis	reis	NOUN
biomedich-176	31	34	et	et	NOUN
biomedich-176	31	35	al	al	PROPN
biomedich-176	31	36	.	.	PROPN
biomedich-176	31	37	,	,	PUNCT
biomedich-176	31	38	2005	2005	NUM
biomedich-176	31	39	)	)	PUNCT
biomedich-176	31	40	.	.	PUNCT
biomedich-176	32	1	characterization	characterization	NOUN
biomedich-176	32	2	types	type	NOUN
biomedich-176	32	3	of	of	ADP
biomedich-176	32	4	breast	breast	NOUN
biomedich-176	32	5	cancer	cancer	NOUN
biomedich-176	32	6	over	over	ADP
biomedich-176	32	7	100	100	NUM
biomedich-176	32	8	types	type	NOUN
biomedich-176	32	9	of	of	ADP
biomedich-176	32	10	cancers	cancer	NOUN
biomedich-176	32	11	consist	consist	VERB
biomedich-176	32	12	of	of	ADP
biomedich-176	32	13	multiple	multiple	ADJ
biomedich-176	32	14	subtypes	subtype	NOUN
biomedich-176	32	15	capable	capable	ADJ
biomedich-176	32	16	of	of	ADP
biomedich-176	32	17	arising	arise	VERB
biomedich-176	32	18	in	in	ADP
biomedich-176	32	19	a	a	DET
biomedich-176	32	20	single	single	ADJ
biomedich-176	32	21	type	type	NOUN
biomedich-176	32	22	of	of	ADP
biomedich-176	32	23	organ	organ	NOUN
biomedich-176	32	24	or	or	CCONJ
biomedich-176	32	25	tissue	tissue	NOUN
biomedich-176	32	26	.	.	PUNCT
biomedich-176	33	1	most	most	ADJ
biomedich-176	33	2	cancers	cancer	NOUN
biomedich-176	33	3	can	can	AUX
biomedich-176	33	4	be	be	AUX
biomedich-176	33	5	defined	define	VERB
biomedich-176	33	6	at	at	ADP
biomedich-176	33	7	a	a	DET
biomedich-176	33	8	very	very	ADV
biomedich-176	33	9	general	general	ADJ
biomedich-176	33	10	level	level	NOUN
biomedich-176	33	11	based	base	VERB
biomedich-176	33	12	on	on	ADP
biomedich-176	33	13	their	their	PRON
biomedich-176	33	14	originating	originate	VERB
biomedich-176	33	15	tissue	tissue	NOUN
biomedich-176	33	16	location	location	NOUN
biomedich-176	33	17	.	.	PUNCT
biomedich-176	34	1	in	in	ADP
biomedich-176	34	2	epithelial	epithelial	ADJ
biomedich-176	34	3	cells	cell	NOUN
biomedich-176	34	4	,	,	PUNCT
biomedich-176	34	5	the	the	DET
biomedich-176	34	6	most	most	ADV
biomedich-176	34	7	common	common	ADJ
biomedich-176	34	8	type	type	NOUN
biomedich-176	34	9	of	of	ADP
biomedich-176	34	10	cancer	cancer	NOUN
biomedich-176	34	11	,	,	PUNCT
biomedich-176	34	12	comprising	comprise	VERB
biomedich-176	34	13	more	more	ADJ
biomedich-176	34	14	than	than	ADP
biomedich-176	34	15	80	80	NUM
biomedich-176	34	16	per	per	ADP
biomedich-176	34	17	cent	cent	NOUN
biomedich-176	34	18	of	of	ADP
biomedich-176	34	19	all	all	DET
biomedich-176	34	20	cancers	cancer	NOUN
biomedich-176	34	21	,	,	PUNCT
biomedich-176	34	22	occurs	occur	VERB
biomedich-176	34	23	;	;	PUNCT
biomedich-176	34	24	these	these	DET
biomedich-176	34	25	cancers	cancer	NOUN
biomedich-176	34	26	are	be	AUX
biomedich-176	34	27	called	call	VERB
biomedich-176	34	28	carcinomas	carcinoma	NOUN
biomedich-176	34	29	.	.	PUNCT
biomedich-176	35	1	depending	depend	VERB
biomedich-176	35	2	on	on	ADP
biomedich-176	35	3	whether	whether	SCONJ
biomedich-176	35	4	the	the	DET
biomedich-176	35	5	epithelial	epithelial	ADJ
biomedich-176	35	6	cells	cell	NOUN
biomedich-176	35	7	of	of	ADP
biomedich-176	35	8	origin	origin	NOUN
biomedich-176	35	9	are	be	AUX
biomedich-176	35	10	part	part	NOUN
biomedich-176	35	11	of	of	ADP
biomedich-176	35	12	the	the	DET
biomedich-176	35	13	protective	protective	ADJ
biomedich-176	35	14	epithelial	epithelial	ADJ
biomedich-176	35	15	layer	layer	NOUN
biomedich-176	35	16	(	(	PUNCT
biomedich-176	35	17	squamous	squamous	ADJ
biomedich-176	35	18	cell	cell	NOUN
biomedich-176	35	19	carcinomas	carcinoma	NOUN
biomedich-176	35	20	)	)	PUNCT
biomedich-176	35	21	or	or	CCONJ
biomedich-176	35	22	have	have	VERB
biomedich-176	35	23	secretory	secretory	ADJ
biomedich-176	35	24	properties	property	NOUN
biomedich-176	35	25	(	(	PUNCT
biomedich-176	35	26	adenocarcinomas	adenocarcinoma	NOUN
biomedich-176	35	27	)	)	PUNCT
biomedich-176	35	28	,	,	PUNCT
biomedich-176	35	29	most	most	ADJ
biomedich-176	35	30	carcinomas	carcinoma	NOUN
biomedich-176	35	31	can	can	AUX
biomedich-176	35	32	break	break	VERB
biomedich-176	35	33	into	into	ADP
biomedich-176	35	34	squamous	squamous	ADJ
biomedich-176	35	35	cell	cell	NOUN
biomedich-176	35	36	carcinomas	carcinoma	NOUN
biomedich-176	35	37	or	or	CCONJ
biomedich-176	35	38	adenocarcinomas	adenocarcinoma	NOUN
biomedich-176	35	39	(	(	PUNCT
biomedich-176	35	40	smail	smail	NOUN
biomedich-176	35	41	2016	2016	NUM
biomedich-176	35	42	and	and	CCONJ
biomedich-176	35	43	smail	smail	NOUN
biomedich-176	35	44	2020	2020	NUM
biomedich-176	35	45	)	)	PUNCT
biomedich-176	35	46	.	.	PUNCT
biomedich-176	36	1	breast	breast	NOUN
biomedich-176	36	2	cancers	cancer	NOUN
biomedich-176	36	3	are	be	AUX
biomedich-176	36	4	a	a	DET
biomedich-176	36	5	complex	complex	ADJ
biomedich-176	36	6	and	and	CCONJ
biomedich-176	36	7	heterogeneous	heterogeneous	ADJ
biomedich-176	36	8	community	community	NOUN
biomedich-176	36	9	of	of	ADP
biomedich-176	36	10	diseases	disease	NOUN
biomedich-176	36	11	,	,	PUNCT
biomedich-176	36	12	and	and	CCONJ
biomedich-176	36	13	patients	patient	NOUN
biomedich-176	36	14	are	be	AUX
biomedich-176	36	15	treated	treat	VERB
biomedich-176	36	16	with	with	ADP
biomedich-176	36	17	clinicopathological	clinicopathological	ADJ
biomedich-176	36	18	features	feature	NOUN
biomedich-176	36	19	and	and	CCONJ
biomedich-176	36	20	estrogen	estrogen	NOUN
biomedich-176	36	21	receptor	receptor	NOUN
biomedich-176	36	22	status	status	NOUN
biomedich-176	36	23	and	and	CCONJ
biomedich-176	36	24	her2	her2	PROPN
biomedich-176	36	25	guidance	guidance	NOUN
biomedich-176	36	26	.	.	PUNCT
biomedich-176	37	1	however	however	ADV
biomedich-176	37	2	,	,	PUNCT
biomedich-176	37	3	for	for	ADP
biomedich-176	37	4	the	the	DET
biomedich-176	37	5	individualization	individualization	NOUN
biomedich-176	37	6	of	of	ADP
biomedich-176	37	7	treatment	treatment	NOUN
biomedich-176	37	8	,	,	PUNCT
biomedich-176	37	9	these	these	DET
biomedich-176	37	10	factors	factor	NOUN
biomedich-176	37	11	are	be	AUX
biomedich-176	37	12	not	not	PART
biomedich-176	37	13	necessary	necessary	ADJ
biomedich-176	37	14	.	.	PUNCT
biomedich-176	38	1	microarray	microarray	NOUN
biomedich-176	38	2	-	-	PUNCT
biomedich-176	38	3	based	base	VERB
biomedich-176	38	4	gene	gene	NOUN
biomedich-176	38	5	expression	expression	NOUN
biomedich-176	38	6	profiling	profiling	NOUN
biomedich-176	38	7	has	have	AUX
biomedich-176	38	8	contributed	contribute	VERB
biomedich-176	38	9	to	to	ADP
biomedich-176	38	10	a	a	DET
biomedich-176	38	11	paradigm	paradigm	NOUN
biomedich-176	38	12	change	change	NOUN
biomedich-176	38	13	in	in	ADP
biomedich-176	38	14	the	the	DET
biomedich-176	38	15	understanding	understanding	NOUN
biomedich-176	38	16	of	of	ADP
biomedich-176	38	17	breast	breast	NOUN
biomedich-176	38	18	cancer	cancer	NOUN
biomedich-176	38	19	.	.	PUNCT
biomedich-176	39	1	it	it	PRON
biomedich-176	39	2	has	have	AUX
biomedich-176	39	3	been	be	AUX
biomedich-176	39	4	shown	show	VERB
biomedich-176	39	5	conclusively	conclusively	ADV
biomedich-176	39	6	that	that	SCONJ
biomedich-176	39	7	breast	breast	NOUN
biomedich-176	39	8	cancer	cancer	NOUN
biomedich-176	39	9	is	be	AUX
biomedich-176	39	10	not	not	PART
biomedich-176	39	11	a	a	DET
biomedich-176	39	12	single	single	ADJ
biomedich-176	39	13	disease	disease	NOUN
biomedich-176	39	14	(	(	PUNCT
biomedich-176	39	15	weigelt	weigelt	PROPN
biomedich-176	39	16	et	et	PROPN
biomedich-176	39	17	al	al	PROPN
biomedich-176	39	18	.	.	PROPN
biomedich-176	39	19	,2010	,2010	PUNCT
biomedich-176	39	20	)	)	PUNCT
biomedich-176	39	21	.	.	PUNCT
biomedich-176	40	1	joint	joint	ADJ
biomedich-176	40	2	hormone	hormone	NOUN
biomedich-176	40	3	receptor	receptor	NOUN
biomedich-176	40	4	-	-	PUNCT
biomedich-176	40	5	defined	define	VERB
biomedich-176	40	6	subtypes	subtype	NOUN
biomedich-176	40	7	of	of	ADP
biomedich-176	40	8	breast	breast	NOUN
biomedich-176	40	9	cancer	cancer	NOUN
biomedich-176	40	10	(	(	PUNCT
biomedich-176	40	11	h.r	h.r	PROPN
biomedich-176	40	12	.	.	PROPN
biomedich-176	40	13	;	;	PUNCT
biomedich-176	40	14	estrogen	estrogen	NOUN
biomedich-176	40	15	receptor	receptor	NOUN
biomedich-176	41	1	[	[	X
biomedich-176	41	2	e.r	e.r	PROPN
biomedich-176	41	3	.	.	NOUN
biomedich-176	41	4	]	]	PUNCT
biomedich-176	41	5	and	and	CCONJ
biomedich-176	41	6	progesterone	progesterone	NOUN
biomedich-176	41	7	receptor	receptor	NOUN
biomedich-176	41	8	[	[	X
biomedich-176	41	9	p.r	p.r	NOUN
biomedich-176	41	10	.	.	PROPN
biomedich-176	41	11	]	]	PUNCT
biomedich-176	41	12	)	)	PUNCT
biomedich-176	41	13	and	and	CCONJ
biomedich-176	41	14	her2	her2	VERB
biomedich-176	41	15	status	status	NOUN
biomedich-176	41	16	(	(	PUNCT
biomedich-176	41	17	howlade	howlade	PROPN
biomedich-176	41	18	et	et	PROPN
biomedich-176	41	19	al	al	PROPN
biomedich-176	41	20	.	.	PROPN
biomedich-176	41	21	,	,	PUNCT
biomedich-176	41	22	2014	2014	NUM
biomedich-176	41	23	)	)	PUNCT
biomedich-176	41	24	.	.	PUNCT
biomedich-176	42	1	triple	triple	ADJ
biomedich-176	42	2	-	-	PUNCT
biomedich-176	42	3	negative	negative	ADJ
biomedich-176	42	4	(	(	PUNCT
biomedich-176	42	5	tnbc	tnbc	ADJ
biomedich-176	42	6	)	)	PUNCT
biomedich-176	42	7	breast	breast	NOUN
biomedich-176	42	8	cancers	cancer	NOUN
biomedich-176	42	9	do	do	AUX
biomedich-176	42	10	not	not	PART
biomedich-176	42	11	express	express	VERB
biomedich-176	42	12	hormone	hormone	NOUN
biomedich-176	42	13	receptors	receptor	NOUN
biomedich-176	42	14	or	or	CCONJ
biomedich-176	42	15	over	over	ADP
biomedich-176	42	16	-	-	PUNCT
biomedich-176	42	17	express	express	NOUN
biomedich-176	42	18	her2	her2	PROPN
biomedich-176	42	19	.	.	PUNCT
biomedich-176	43	1	as	as	SCONJ
biomedich-176	43	2	characterized	characterize	VERB
biomedich-176	43	3	by	by	ADP
biomedich-176	43	4	low	low	ADJ
biomedich-176	43	5	five	five	NUM
biomedich-176	43	6	-	-	PUNCT
biomedich-176	43	7	year	year	NOUN
biomedich-176	43	8	survival	survival	NOUN
biomedich-176	43	9	and	and	CCONJ
biomedich-176	43	10	high	high	ADJ
biomedich-176	43	11	recurrence	recurrence	NOUN
biomedich-176	43	12	rates	rate	NOUN
biomedich-176	43	13	after	after	ADP
biomedich-176	43	14	adjuvant	adjuvant	ADJ
biomedich-176	43	15	therapy	therapy	NOUN
biomedich-176	43	16	,	,	PUNCT
biomedich-176	43	17	poor	poor	ADJ
biomedich-176	43	18	prognosis	prognosis	NOUN
biomedich-176	43	19	is	be	AUX
biomedich-176	43	20	associated	associate	VERB
biomedich-176	43	21	with	with	ADP
biomedich-176	43	22	these	these	DET
biomedich-176	43	23	conditions	condition	NOUN
biomedich-176	43	24	.	.	PUNCT
biomedich-176	44	1	overall	overall	ADV
biomedich-176	44	2	,	,	PUNCT
biomedich-176	44	3	tnbc	tnbc	PROPN
biomedich-176	44	4	has	have	AUX
biomedich-176	44	5	striking	strike	VERB
biomedich-176	44	6	similarities	similarity	NOUN
biomedich-176	44	7	with	with	ADP
biomedich-176	44	8	basal	basal	NOUN
biomedich-176	44	9	-	-	PUNCT
biomedich-176	44	10	like	like	ADJ
biomedich-176	44	11	breast	breast	NOUN
biomedich-176	44	12	cancers	cancer	NOUN
biomedich-176	44	13	(	(	PUNCT
biomedich-176	44	14	bbc	bbc	PROPN
biomedich-176	44	15	)	)	PUNCT
biomedich-176	44	16	,	,	PUNCT
biomedich-176	44	17	but	but	CCONJ
biomedich-176	44	18	they	they	PRON
biomedich-176	44	19	are	be	AUX
biomedich-176	44	20	found	find	VERB
biomedich-176	44	21	the	the	DET
biomedich-176	44	22	same	same	ADJ
biomedich-176	44	23	in	in	ADP
biomedich-176	44	24	various	various	ADJ
biomedich-176	44	25	studies	study	NOUN
biomedich-176	44	26	(	(	PUNCT
biomedich-176	44	27	de	de	X
biomedich-176	44	28	et	et	PROPN
biomedich-176	44	29	al	al	PROPN
biomedich-176	44	30	.	.	PROPN
biomedich-176	44	31	,	,	PUNCT
biomedich-176	44	32	2011	2011	NUM
biomedich-176	44	33	)	)	PUNCT
biomedich-176	44	34	.	.	PUNCT
biomedich-176	45	1	five	five	NUM
biomedich-176	45	2	tumour	tumour	ADJ
biomedich-176	45	3	subtypes	subtype	NOUN
biomedich-176	45	4	(	(	PUNCT
biomedich-176	45	5	luminal	luminal	NOUN
biomedich-176	45	6	a	a	PRON
biomedich-176	45	7	,	,	PUNCT
biomedich-176	45	8	luminal	luminal	ADJ
biomedich-176	45	9	b	b	NOUN
biomedich-176	45	10	,	,	PUNCT
biomedich-176	45	11	her2	her2	PROPN
biomedich-176	45	12	-	-	PUNCT
biomedich-176	45	13	enriched	enrich	VERB
biomedich-176	45	14	,	,	PUNCT
biomedich-176	45	15	basal	basal	NOUN
biomedich-176	45	16	,	,	PUNCT
biomedich-176	45	17	and	and	CCONJ
biomedich-176	45	18	claudin	claudin	VERB
biomedich-176	45	19	-	-	PUNCT
biomedich-176	45	20	low	low	NOUN
biomedich-176	45	21	)	)	PUNCT
biomedich-176	45	22	have	have	AUX
biomedich-176	45	23	been	be	AUX
biomedich-176	45	24	identified	identify	VERB
biomedich-176	45	25	in	in	ADP
biomedich-176	45	26	breast	breast	NOUN
biomedich-176	45	27	cancer	cancer	NOUN
biomedich-176	45	28	gene	gene	NOUN
biomedich-176	45	29	expression	expression	NOUN
biomedich-176	45	30	studies	study	NOUN
biomedich-176	45	31	,	,	PUNCT
biomedich-176	45	32	each	each	PRON
biomedich-176	45	33	of	of	ADP
biomedich-176	45	34	which	which	PRON
biomedich-176	45	35	has	have	VERB
biomedich-176	45	36	specific	specific	ADJ
biomedich-176	45	37	biological	biological	ADJ
biomedich-176	45	38	and	and	CCONJ
biomedich-176	45	39	prognostic	prognostic	ADJ
biomedich-176	45	40	features	feature	NOUN
biomedich-176	45	41	(	(	PUNCT
biomedich-176	45	42	prat	prat	NOUN
biomedich-176	45	43	et	et	PROPN
biomedich-176	45	44	al	al	PROPN
biomedich-176	45	45	.	.	PROPN
biomedich-176	45	46	,2010	,2010	PUNCT
biomedich-176	45	47	)	)	PUNCT
biomedich-176	45	48	.	.	PUNCT
biomedich-176	46	1	four	four	NUM
biomedich-176	46	2	major	major	ADJ
biomedich-176	46	3	intrinsic	intrinsic	ADJ
biomedich-176	46	4	molecular	molecular	ADJ
biomedich-176	46	5	subtypes	subtype	NOUN
biomedich-176	46	6	of	of	ADP
biomedich-176	46	7	breast	breast	NOUN
biomedich-176	46	8	cancer	cancer	NOUN
biomedich-176	46	9	,	,	PUNCT
biomedich-176	46	10	known	know	VERB
biomedich-176	46	11	as	as	ADP
biomedich-176	46	12	luminal	luminal	ADJ
biomedich-176	46	13	a	a	PRON
biomedich-176	46	14	,	,	PUNCT
biomedich-176	46	15	luminal	luminal	ADJ
biomedich-176	46	16	b	b	NOUN
biomedich-176	46	17	,	,	PUNCT
biomedich-176	46	18	her2	her2	PROPN
biomedich-176	46	19	-	-	PUNCT
biomedich-176	46	20	enriched	enrich	VERB
biomedich-176	47	1	[	[	X
biomedich-176	47	2	her2e	her2e	X
biomedich-176	47	3	]	]	X
biomedich-176	47	4	,	,	PUNCT
biomedich-176	47	5	and	and	CCONJ
biomedich-176	47	6	basal	basal	NOUN
biomedich-176	47	7	-	-	PUNCT
biomedich-176	47	8	like	like	NOUN
biomedich-176	47	9	,	,	PUNCT
biomedich-176	47	10	were	be	AUX
biomedich-176	47	11	identified	identify	VERB
biomedich-176	47	12	in	in	ADP
biomedich-176	47	13	global	global	ADJ
biomedich-176	47	14	gene	gene	NOUN
biomedich-176	47	15	expression	expression	NOUN
biomedich-176	47	16	analysis	analysis	NOUN
biomedich-176	47	17	studies	study	NOUN
biomedich-176	47	18	.	.	PUNCT
biomedich-176	48	1	these	these	DET
biomedich-176	48	2	molecular	molecular	ADJ
biomedich-176	48	3	entities	entity	NOUN
biomedich-176	48	4	have	have	AUX
biomedich-176	48	5	shown	show	VERB
biomedich-176	48	6	major	major	ADJ
biomedich-176	48	7	differences	difference	NOUN
biomedich-176	48	8	in	in	ADP
biomedich-176	48	9	terms	term	NOUN
biomedich-176	48	10	of	of	ADP
biomedich-176	48	11	occurrence	occurrence	NOUN
biomedich-176	48	12	,	,	PUNCT
biomedich-176	48	13	risk	risk	NOUN
biomedich-176	48	14	factors	factor	NOUN
biomedich-176	48	15	,	,	PUNCT
biomedich-176	48	16	baseline	baseline	ADJ
biomedich-176	48	17	prognosis	prognosis	NOUN
biomedich-176	48	18	,	,	PUNCT
biomedich-176	48	19	age	age	NOUN
biomedich-176	48	20	at	at	ADP
biomedich-176	48	21	diagnosis	diagnosis	NOUN
biomedich-176	48	22	,	,	PUNCT
biomedich-176	48	23	and	and	CCONJ
biomedich-176	48	24	response	response	NOUN
biomedich-176	48	25	to	to	ADP
biomedich-176	48	26	treatment	treatment	NOUN
biomedich-176	48	27	.	.	PUNCT
biomedich-176	49	1	because	because	SCONJ
biomedich-176	49	2	of	of	ADP
biomedich-176	49	3	its	its	PRON
biomedich-176	49	4	high	high	ADJ
biomedich-176	49	5	frequency	frequency	NOUN
biomedich-176	49	6	,	,	PUNCT
biomedich-176	49	7	lack	lack	NOUN
biomedich-176	49	8	of	of	ADP
biomedich-176	49	9	successful	successful	ADJ
biomedich-176	49	10	targeted	target	VERB
biomedich-176	49	11	therapies	therapy	NOUN
biomedich-176	49	12	,	,	PUNCT
biomedich-176	49	13	weak	weak	ADJ
biomedich-176	49	14	baseline	baseline	NOUN
biomedich-176	49	15	prognosis	prognosis	NOUN
biomedich-176	49	16	,	,	PUNCT
biomedich-176	49	17	and	and	CCONJ
biomedich-176	49	18	propensity	propensity	NOUN
biomedich-176	49	19	to	to	PART
biomedich-176	49	20	impact	impact	VERB
biomedich-176	49	21	younger	young	ADJ
biomedich-176	49	22	women	woman	NOUN
biomedich-176	49	23	,	,	PUNCT
biomedich-176	49	24	the	the	DET
biomedich-176	49	25	basal	basal	NOUN
biomedich-176	49	26	-	-	PUNCT
biomedich-176	49	27	like	like	ADJ
biomedich-176	49	28	subtype	subtype	NOUN
biomedich-176	49	29	is	be	AUX
biomedich-176	49	30	of	of	ADP
biomedich-176	49	31	particular	particular	ADJ
biomedich-176	49	32	clinical	clinical	ADJ
biomedich-176	49	33	concern	concern	NOUN
biomedich-176	49	34	(	(	PUNCT
biomedich-176	49	35	prat	prat	NOUN
biomedich-176	49	36	et	et	PROPN
biomedich-176	49	37	al	al	PROPN
biomedich-176	49	38	.	.	PROPN
biomedich-176	49	39	,	,	PUNCT
biomedich-176	49	40	2013	2013	NUM
biomedich-176	49	41	)	)	PUNCT
biomedich-176	49	42	.	.	PUNCT
biomedich-176	50	1	a	a	DET
biomedich-176	50	2	promising	promising	ADJ
biomedich-176	50	3	new	new	ADJ
biomedich-176	50	4	diagnostic	diagnostic	ADJ
biomedich-176	50	5	area	area	NOUN
biomedich-176	50	6	for	for	ADP
biomedich-176	50	7	estimating	estimate	VERB
biomedich-176	50	8	the	the	DET
biomedich-176	50	9	risk	risk	NOUN
biomedich-176	50	10	for	for	ADP
biomedich-176	50	11	metastatic	metastatic	ADJ
biomedich-176	50	12	relapse	relapse	NOUN
biomedich-176	50	13	and	and	CCONJ
biomedich-176	50	14	metastatic	metastatic	ADJ
biomedich-176	50	15	progression	progression	NOUN
biomedich-176	50	16	in	in	ADP
biomedich-176	50	17	cancer	cancer	NOUN
biomedich-176	50	18	patients	patient	NOUN
biomedich-176	50	19	is	be	AUX
biomedich-176	50	20	the	the	DET
biomedich-176	50	21	circulating	circulate	VERB
biomedich-176	50	22	tumor	tumor	NOUN
biomedich-176	50	23	cell	cell	NOUN
biomedich-176	50	24	(	(	PUNCT
biomedich-176	50	25	ctc	ctc	NOUN
biomedich-176	50	26	)	)	PUNCT
biomedich-176	50	27	study	study	NOUN
biomedich-176	50	28	(	(	PUNCT
biomedich-176	50	29	lianidou	lianidou	NOUN
biomedich-176	50	30	et	et	PROPN
biomedich-176	50	31	al	al	PROPN
biomedich-176	50	32	.	.	PROPN
biomedich-176	50	33	,	,	PUNCT
biomedich-176	50	34	2011	2011	NUM
biomedich-176	50	35	)	)	PUNCT
biomedich-176	50	36	.	.	PUNCT
biomedich-176	51	1	rna	rna	NOUN
biomedich-176	51	2	sequencing	sequencing	NOUN
biomedich-176	51	3	found	find	VERB
biomedich-176	51	4	that	that	SCONJ
biomedich-176	51	5	pdx	pdx	PROPN
biomedich-176	51	6	cells	cell	NOUN
biomedich-176	51	7	developed	develop	VERB
biomedich-176	51	8	in	in	ADP
biomedich-176	51	9	the	the	DET
biomedich-176	51	10	mammary	mammary	ADJ
biomedich-176	51	11	gland	gland	NOUN
biomedich-176	51	12	were	be	AUX
biomedich-176	51	13	identical	identical	ADJ
biomedich-176	51	14	to	to	ADP
biomedich-176	51	15	those	those	PRON
biomedich-176	51	16	studied	study	VERB
biomedich-176	51	17	in	in	ADP
biomedich-176	51	18	culture	culture	NOUN
biomedich-176	51	19	for	for	ADP
biomedich-176	51	20	global	global	ADJ
biomedich-176	51	21	gene	gene	NOUN
biomedich-176	51	22	expression	expression	NOUN
biomedich-176	51	23	.	.	PUNCT
biomedich-176	52	1	carboplatin	carboplatin	PROPN
biomedich-176	52	2	was	be	AUX
biomedich-176	52	3	cytotoxic	cytotoxic	ADJ
biomedich-176	52	4	to	to	PART
biomedich-176	52	5	whim30	whim30	VERB
biomedich-176	52	6	but	but	CCONJ
biomedich-176	52	7	not	not	PART
biomedich-176	52	8	whim2	whim2	VERB
biomedich-176	52	9	in	in	ADP
biomedich-176	52	10	vitro	vitro	X
biomedich-176	52	11	,	,	PUNCT
biomedich-176	52	12	while	while	SCONJ
biomedich-176	52	13	both	both	DET
biomedich-176	52	14	lines	line	NOUN
biomedich-176	52	15	were	be	AUX
biomedich-176	52	16	cytotoxic	cytotoxic	ADJ
biomedich-176	52	17	to	to	PART
biomedich-176	52	18	bortezomib	bortezomib	VERB
biomedich-176	52	19	,	,	PUNCT
biomedich-176	52	20	dacarbazine	dacarbazine	NOUN
biomedich-176	52	21	,	,	PUNCT
biomedich-176	52	22	and	and	CCONJ
biomedich-176	52	23	cyclophosphamide	cyclophosphamide	NOUN
biomedich-176	52	24	.	.	PUNCT
biomedich-176	53	1	however	however	ADV
biomedich-176	53	2	,	,	PUNCT
biomedich-176	53	3	these	these	DET
biomedich-176	53	4	drugs	drug	NOUN
biomedich-176	53	5	have	have	AUX
biomedich-176	53	6	proven	prove	VERB
biomedich-176	53	7	unsuccessful	unsuccessful	ADJ
biomedich-176	53	8	in	in	ADP
biomedich-176	53	9	treating	treat	VERB
biomedich-176	53	10	in	in	ADP
biomedich-176	53	11	vivo	vivo	NOUN
biomedich-176	53	12	both	both	CCONJ
biomedich-176	53	13	primary	primary	ADJ
biomedich-176	53	14	and	and	CCONJ
biomedich-176	53	15	metastatic	metastatic	ADJ
biomedich-176	53	16	whim2	whim2	NOUN
biomedich-176	54	1	tumours	tumours	X
biomedich-176	54	2	.	.	PUNCT
biomedich-176	55	1	on	on	ADP
biomedich-176	55	2	the	the	DET
biomedich-176	55	3	other	other	ADJ
biomedich-176	55	4	hand	hand	NOUN
biomedich-176	55	5	,	,	PUNCT
biomedich-176	55	6	carboplatin	carboplatin	NOUN
biomedich-176	55	7	and	and	CCONJ
biomedich-176	55	8	cyclophosphamide	cyclophosphamide	NOUN
biomedich-176	55	9	have	have	AUX
biomedich-176	55	10	successfully	successfully	ADV
biomedich-176	55	11	treated	treat	VERB
biomedich-176	55	12	whim30	whim30	NOUN
biomedich-176	55	13	mammary	mammary	ADJ
biomedich-176	55	14	tumours	tumour	NOUN
biomedich-176	55	15	and	and	CCONJ
biomedich-176	55	16	reduced	reduced	ADJ
biomedich-176	55	17	brain	brain	NOUN
biomedich-176	55	18	,	,	PUNCT
biomedich-176	55	19	liver	liver	NOUN
biomedich-176	55	20	,	,	PUNCT
biomedich-176	55	21	and	and	CCONJ
biomedich-176	55	22	lung	lung	NOUN
biomedich-176	55	23	metastatic	metastatic	ADJ
biomedich-176	55	24	burden	burden	NOUN
biomedich-176	55	25	(	(	PUNCT
biomedich-176	55	26	turner	turner	PROPN
biomedich-176	55	27	et	et	PROPN
biomedich-176	55	28	al	al	PROPN
biomedich-176	55	29	.	.	PROPN
biomedich-176	55	30	,	,	PUNCT
biomedich-176	55	31	2018	2018	NUM
biomedich-176	55	32	)	)	PUNCT
biomedich-176	55	33	.	.	PUNCT
biomedich-176	56	1	the	the	DET
biomedich-176	56	2	metastatic	metastatic	ADJ
biomedich-176	56	3	cascade	cascade	NOUN
biomedich-176	56	4	is	be	AUX
biomedich-176	56	5	a	a	DET
biomedich-176	56	6	series	series	NOUN
biomedich-176	56	7	of	of	ADP
biomedich-176	56	8	biological	biological	ADJ
biomedich-176	56	9	processes	process	NOUN
biomedich-176	56	10	that	that	PRON
biomedich-176	56	11	cause	cause	VERB
biomedich-176	56	12	tumour	tumour	NOUN
biomedich-176	56	13	cells	cell	NOUN
biomedich-176	56	14	to	to	PART
biomedich-176	56	15	migrate	migrate	VERB
biomedich-176	56	16	from	from	ADP
biomedich-176	56	17	the	the	DET
biomedich-176	56	18	primary	primary	ADJ
biomedich-176	56	19	site	site	NOUN
biomedich-176	56	20	to	to	ADP
biomedich-176	56	21	a	a	DET
biomedich-176	56	22	distant	distant	ADJ
biomedich-176	56	23	location	location	NOUN
biomedich-176	56	24	and	and	CCONJ
biomedich-176	56	25	create	create	VERB
biomedich-176	56	26	new	new	ADJ
biomedich-176	56	27	cancer	cancer	NOUN
biomedich-176	56	28	growth	growth	NOUN
biomedich-176	56	29	.	.	PUNCT
biomedich-176	57	1	circular	circular	ADJ
biomedich-176	57	2	tumour	tumour	NOUN
biomedich-176	57	3	cells	cell	NOUN
biomedich-176	57	4	(	(	PUNCT
biomedich-176	57	5	ctcs	ctcs	NOUN
biomedich-176	57	6	)	)	PUNCT
biomedich-176	57	7	play	play	VERB
biomedich-176	57	8	a	a	DET
biomedich-176	57	9	crucial	crucial	ADJ
biomedich-176	57	10	role	role	NOUN
biomedich-176	57	11	in	in	ADP
biomedich-176	57	12	tumour	tumour	ADJ
biomedich-176	57	13	propagation	propagation	NOUN
biomedich-176	57	14	.	.	PUNCT
biomedich-176	58	1	the	the	DET
biomedich-176	58	2	role	role	NOUN
biomedich-176	58	3	of	of	ADP
biomedich-176	58	4	ctcs	ctcs	NOUN
biomedich-176	58	5	in	in	ADP
biomedich-176	58	6	treatment	treatment	NOUN
biomedich-176	58	7	failure	failure	NOUN
biomedich-176	58	8	and	and	CCONJ
biomedich-176	58	9	disease	disease	NOUN
biomedich-176	58	10	progression	progression	NOUN
biomedich-176	58	11	can	can	AUX
biomedich-176	58	12	be	be	AUX
biomedich-176	58	13	explained	explain	VERB
biomedich-176	58	14	by	by	ADP
biomedich-176	58	15	their	their	PRON
biomedich-176	58	16	association	association	NOUN
biomedich-176	58	17	with	with	ADP
biomedich-176	58	18	biological	biological	ADJ
biomedich-176	58	19	processes	process	NOUN
biomedich-176	58	20	,	,	PUNCT
biomedich-176	58	21	including	include	VERB
biomedich-176	58	22	epithelial	epithelial	ADJ
biomedich-176	58	23	-	-	PUNCT
biomedich-176	58	24	tomesenchymal	tomesenchymal	ADJ
biomedich-176	58	25	transformation	transformation	NOUN
biomedich-176	58	26	and	and	CCONJ
biomedich-176	58	27	self	self	NOUN
biomedich-176	58	28	-	-	PUNCT
biomedich-176	58	29	seeding	seeding	NOUN
biomedich-176	58	30	,	,	PUNCT
biomedich-176	58	31	defined	define	VERB
biomedich-176	58	32	as	as	ADP
biomedich-176	58	33	primary	primary	ADJ
biomedich-176	58	34	infiltration	infiltration	NOUN
biomedich-176	58	35	of	of	ADP
biomedich-176	58	36	the	the	DET
biomedich-176	58	37	tumour	tumour	NOUN
biomedich-176	58	38	or	or	CCONJ
biomedich-176	58	39	metastasis	metastasis	NOUN
biomedich-176	58	40	formed	form	VERB
biomedich-176	58	41	by	by	ADP
biomedich-176	58	42	more	more	ADV
biomedich-176	58	43	aggressive	aggressive	ADJ
biomedich-176	58	44	ctcs	ctcs	NOUN
biomedich-176	58	45	.	.	PUNCT
biomedich-176	59	1	ctcs	ctcs	PROPN
biomedich-176	59	2	are	be	AUX
biomedich-176	59	3	a	a	DET
biomedich-176	59	4	rare	rare	ADJ
biomedich-176	59	5	and	and	CCONJ
biomedich-176	59	6	heterogeneous	heterogeneous	ADJ
biomedich-176	59	7	population	population	NOUN
biomedich-176	59	8	of	of	ADP
biomedich-176	59	9	cells	cell	NOUN
biomedich-176	59	10	of	of	ADP
biomedich-176	59	11	proven	prove	VERB
biomedich-176	59	12	prognostic	prognostic	ADJ
biomedich-176	59	13	and	and	CCONJ
biomedich-176	59	14	predictive	predictive	ADJ
biomedich-176	59	15	value	value	NOUN
biomedich-176	59	16	in	in	ADP
biomedich-176	59	17	some	some	DET
biomedich-176	59	18	clinical	clinical	ADJ
biomedich-176	59	19	contexts	contexts	NOUN
biomedich-176	59	20	(	(	PUNCT
biomedich-176	59	21	mego	mego	NOUN
biomedich-176	59	22	et	et	PROPN
biomedich-176	59	23	al	al	PROPN
biomedich-176	59	24	.	.	PROPN
biomedich-176	59	25	,	,	PUNCT
biomedich-176	59	26	2010	2010	NUM
biomedich-176	59	27	)	)	PUNCT
biomedich-176	59	28	.	.	PUNCT
biomedich-176	60	1	in	in	ADP
biomedich-176	60	2	addition	addition	NOUN
biomedich-176	60	3	to	to	ADP
biomedich-176	60	4	the	the	DET
biomedich-176	60	5	typical	typical	ADJ
biomedich-176	60	6	hormone	hormone	NOUN
biomedich-176	60	7	receptor	receptor	NOUN
biomedich-176	60	8	-	-	PUNCT
biomedich-176	60	9	positive	positive	ADJ
biomedich-176	60	10	and	and	CCONJ
biomedich-176	60	11	hormone	hormone	NOUN
biomedich-176	60	12	receptor	receptor	NOUN
biomedich-176	60	13	-	-	PUNCT
biomedich-176	60	14	negative	negative	ADJ
biomedich-176	60	15	forms	form	NOUN
biomedich-176	60	16	,	,	PUNCT
biomedich-176	60	17	studies	study	NOUN
biomedich-176	60	18	of	of	ADP
biomedich-176	60	19	breast	breast	NOUN
biomedich-176	60	20	cancers	cancer	NOUN
biomedich-176	60	21	using	use	VERB
biomedich-176	60	22	gene	gene	NOUN
biomedich-176	60	23	expression	expression	NOUN
biomedich-176	60	24	profiling	profiling	NOUN
biomedich-176	60	25	have	have	AUX
biomedich-176	60	26	identified	identify	VERB
biomedich-176	60	27	many	many	ADJ
biomedich-176	60	28	major	major	ADJ
biomedich-176	60	29	breast	breast	NOUN
biomedich-176	60	30	cancer	cancer	NOUN
biomedich-176	60	31	subtypes	subtype	NOUN
biomedich-176	60	32	.	.	PUNCT
biomedich-176	61	1	the	the	DET
biomedich-176	61	2	luminal	luminal	ADJ
biomedich-176	61	3	a	a	PRON
biomedich-176	61	4	and	and	CCONJ
biomedich-176	61	5	luminal	luminal	ADJ
biomedich-176	61	6	b	b	PROPN
biomedich-176	61	7	classes	class	NOUN
biomedich-176	61	8	are	be	AUX
biomedich-176	61	9	the	the	DET
biomedich-176	61	10	most	most	ADV
biomedich-176	61	11	reproducibly	reproducibly	ADV
biomedich-176	61	12	defined	define	VERB
biomedich-176	61	13	molecular	molecular	ADJ
biomedich-176	61	14	subtypes	subtype	NOUN
biomedich-176	61	15	among	among	ADP
biomedich-176	61	16	the	the	DET
biomedich-176	61	17	hormone	hormone	NOUN
biomedich-176	61	18	receptorpositive	receptorpositive	ADJ
biomedich-176	61	19	cancers	cancer	NOUN
biomedich-176	61	20	.	.	PUNCT
biomedich-176	62	1	the	the	DET
biomedich-176	62	2	major	major	ADJ
biomedich-176	62	3	molecular	molecular	ADJ
biomedich-176	62	4	subtypes	subtype	NOUN
biomedich-176	62	5	identified	identify	VERB
biomedich-176	62	6	in	in	ADP
biomedich-176	62	7	hormone	hormone	NOUN
biomedich-176	62	8	-	-	PUNCT
biomedich-176	62	9	receptor	receptor	NOUN
biomedich-176	62	10	-	-	PUNCT
biomedich-176	62	11	negative	negative	ADJ
biomedich-176	62	12	breast	breast	NOUN
biomedich-176	62	13	cancers	cancer	NOUN
biomedich-176	62	14	are	be	AUX
biomedich-176	62	15	the	the	DET
biomedich-176	62	16	her2	her2	PROPN
biomedich-176	62	17	and	and	CCONJ
biomedich-176	62	18	basal	basal	NOUN
biomedich-176	62	19	-	-	PUNCT
biomedich-176	62	20	like	like	ADJ
biomedich-176	62	21	classes	class	NOUN
biomedich-176	62	22	.	.	PUNCT
biomedich-176	63	1	some	some	DET
biomedich-176	63	2	studies	study	NOUN
biomedich-176	63	3	have	have	AUX
biomedich-176	63	4	also	also	ADV
biomedich-176	63	5	described	describe	VERB
biomedich-176	63	6	other	other	ADJ
biomedich-176	63	7	molecular	molecular	ADJ
biomedich-176	63	8	subtypes	subtype	NOUN
biomedich-176	63	9	,	,	PUNCT
biomedich-176	63	10	such	such	ADJ
biomedich-176	63	11	as	as	ADP
biomedich-176	63	12	luminal	luminal	ADJ
biomedich-176	63	13	c	c	NOUN
biomedich-176	63	14	and	and	CCONJ
biomedich-176	63	15	regular	regular	ADJ
biomedich-176	63	16	breast	breast	NOUN
biomedich-176	63	17	-	-	PUNCT
biomedich-176	63	18	like	like	ADJ
biomedich-176	63	19	classes	class	NOUN
biomedich-176	63	20	.	.	PUNCT
biomedich-176	64	1	still	still	ADV
biomedich-176	64	2	,	,	PUNCT
biomedich-176	64	3	they	they	PRON
biomedich-176	64	4	are	be	AUX
biomedich-176	64	5	less	less	ADV
biomedich-176	64	6	well	well	ADV
biomedich-176	64	7	characterized	characterized	ADJ
biomedich-176	64	8	than	than	ADP
biomedich-176	64	9	luminal	luminal	ADJ
biomedich-176	64	10	a	a	DET
biomedich-176	64	11	,	,	PUNCT
biomedich-176	64	12	luminal	luminal	ADJ
biomedich-176	64	13	b	b	NOUN
biomedich-176	64	14	,	,	PUNCT
biomedich-176	64	15	her2	her2	PROPN
biomedich-176	64	16	,	,	PUNCT
biomedich-176	64	17	and	and	CCONJ
biomedich-176	64	18	basal	basal	ADJ
biomedich-176	64	19	types	type	NOUN
biomedich-176	64	20	(	(	PUNCT
biomedich-176	64	21	schnitt	schnitt	NOUN
biomedich-176	64	22	2010	2010	NUM
biomedich-176	64	23	)	)	PUNCT
biomedich-176	64	24	.	.	PUNCT
biomedich-176	65	1	several	several	ADJ
biomedich-176	65	2	molecular	molecular	ADJ
biomedich-176	65	3	-	-	PUNCT
biomedich-176	65	4	targeted	target	VERB
biomedich-176	65	5	therapies	therapy	NOUN
biomedich-176	65	6	for	for	ADP
biomedich-176	65	7	breast	breast	NOUN
biomedich-176	65	8	cancer	cancer	NOUN
biomedich-176	65	9	have	have	AUX
biomedich-176	65	10	been	be	AUX
biomedich-176	65	11	tested	test	VERB
biomedich-176	65	12	since	since	SCONJ
biomedich-176	65	13	the	the	DET
biomedich-176	65	14	application	application	NOUN
biomedich-176	65	15	of	of	ADP
biomedich-176	65	16	endocrine	endocrine	NOUN
biomedich-176	65	17	therapy	therapy	NOUN
biomedich-176	65	18	for	for	ADP
biomedich-176	65	19	estrogen	estrogen	NOUN
biomedich-176	65	20	receptor	receptor	NOUN
biomedich-176	65	21	(	(	PUNCT
biomedich-176	65	22	e.r.)-positive	e.r.)-positive	ADJ
biomedich-176	65	23	tumour	tumour	NOUN
biomedich-176	65	24	types1	types1	PROPN
biomedich-176	65	25	.	.	PUNCT
biomedich-176	66	1	an	an	DET
biomedich-176	66	2	example	example	NOUN
biomedich-176	66	3	of	of	ADP
biomedich-176	66	4	effective	effective	ADJ
biomedich-176	66	5	gene	gene	NOUN
biomedich-176	66	6	-	-	PUNCT
biomedich-176	66	7	targeted	target	VERB
biomedich-176	66	8	therapy	therapy	NOUN
biomedich-176	66	9	is	be	AUX
biomedich-176	66	10	genome	genome	NOUN
biomedich-176	66	11	alteration	alteration	NOUN
biomedich-176	66	12	-	-	PUNCT
biomedich-176	66	13	matched	match	VERB
biomedich-176	66	14	treatment	treatment	NOUN
biomedich-176	66	15	of	of	ADP
biomedich-176	66	16	breast	breast	NOUN
biomedich-176	66	17	cancer	cancer	NOUN
biomedich-176	66	18	to	to	PART
biomedich-176	66	19	target	target	VERB
biomedich-176	66	20	amplification	amplification	NOUN
biomedich-176	66	21	of	of	ADP
biomedich-176	66	22	human	human	ADJ
biomedich-176	66	23	epidermal	epidermal	ADJ
biomedich-176	66	24	growth	growth	NOUN
biomedich-176	66	25	factor	factor	NOUN
biomedich-176	66	26	receptor	receptor	NOUN
biomedich-176	66	27	2	2	NUM
biomedich-176	66	28	genes	gene	NOUN
biomedich-176	66	29	(	(	PUNCT
biomedich-176	66	30	erbb2	erbb2	X
biomedich-176	66	31	receptor	receptor	NOUN
biomedich-176	66	32	tyrosine	tyrosine	PROPN
biomedich-176	66	33	kinase	kinase	PROPN
biomedich-176	66	34	,	,	PUNCT
biomedich-176	66	35	erbb2	erbb2	PROPN
biomedich-176	66	36	also	also	ADV
biomedich-176	66	37	referred	refer	VERB
biomedich-176	66	38	to	to	ADP
biomedich-176	66	39	as	as	ADP
biomedich-176	66	40	her2	her2	PROPN
biomedich-176	66	41	)	)	PUNCT
biomedich-176	66	42	.	.	PUNCT
biomedich-176	67	1	gene	gene	NOUN
biomedich-176	67	2	expression	expression	NOUN
biomedich-176	67	3	-	-	PUNCT
biomedich-176	67	4	based	base	VERB
biomedich-176	67	5	molecular	molecular	ADJ
biomedich-176	67	6	subtyping	subtyping	NOUN
biomedich-176	67	7	has	have	AUX
biomedich-176	67	8	also	also	ADV
biomedich-176	67	9	been	be	AUX
biomedich-176	67	10	broadly	broadly	ADV
biomedich-176	67	11	applied	apply	VERB
biomedich-176	67	12	to	to	ADP
biomedich-176	67	13	breast	breast	NOUN
biomedich-176	67	14	cancer	cancer	NOUN
biomedich-176	67	15	to	to	PART
biomedich-176	67	16	aid	aid	VERB
biomedich-176	67	17	treatment	treatment	NOUN
biomedich-176	67	18	decisions	decision	NOUN
biomedich-176	67	19	(	(	PUNCT
biomedich-176	67	20	chung	chung	PROPN
biomedich-176	67	21	et	et	PROPN
biomedich-176	67	22	al	al	PROPN
biomedich-176	67	23	.	.	PROPN
biomedich-176	67	24	,	,	PUNCT
biomedich-176	67	25	2017	2017	NUM
biomedich-176	67	26	)	)	PUNCT
biomedich-176	67	27	.	.	PUNCT
biomedich-176	68	1	there	there	PRON
biomedich-176	68	2	are	be	VERB
biomedich-176	68	3	many	many	ADJ
biomedich-176	68	4	cellular	cellular	ADJ
biomedich-176	68	5	functions	function	NOUN
biomedich-176	68	6	for	for	ADP
biomedich-176	68	7	brca1	brca1	PROPN
biomedich-176	68	8	.	.	PROPN
biomedich-176	68	9	dna	dna	PROPN
biomedich-176	68	10	repair	repair	PROPN
biomedich-176	68	11	,	,	PUNCT
biomedich-176	68	12	cellcycle	cellcycle	NOUN
biomedich-176	68	13	regulation	regulation	NOUN
biomedich-176	68	14	,	,	PUNCT
biomedich-176	68	15	transcriptional	transcriptional	ADJ
biomedich-176	68	16	regulation	regulation	NOUN
biomedich-176	68	17	,	,	PUNCT
biomedich-176	68	18	and	and	CCONJ
biomedich-176	68	19	chromatin	chromatin	NOUN
biomedich-176	68	20	remodelling	remodelling	NOUN
biomedich-176	68	21	have	have	AUX
biomedich-176	68	22	been	be	AUX
biomedich-176	68	23	implicated	implicate	VERB
biomedich-176	68	24	.	.	PUNCT
biomedich-176	69	1	on	on	ADP
biomedich-176	69	2	the	the	DET
biomedich-176	69	3	contrary	contrary	NOUN
biomedich-176	69	4	,	,	PUNCT
biomedich-176	69	5	functions	function	NOUN
biomedich-176	69	6	assigned	assign	VERB
biomedich-176	69	7	to	to	ADP
biomedich-176	69	8	brca2	brca2	PROPN
biomedich-176	69	9	were	be	AUX
biomedich-176	69	10	specifically	specifically	ADV
biomedich-176	69	11	limited	limit	VERB
biomedich-176	69	12	to	to	ADP
biomedich-176	69	13	dna	dna	NOUN
biomedich-176	69	14	recombination	recombination	NOUN
biomedich-176	69	15	and	and	CCONJ
biomedich-176	69	16	repair	repair	NOUN
biomedich-176	69	17	processes	process	NOUN
biomedich-176	69	18	.	.	PUNCT
biomedich-176	70	1	in	in	ADP
biomedich-176	70	2	the	the	DET
biomedich-176	70	3	regulation	regulation	NOUN
biomedich-176	70	4	of	of	ADP
biomedich-176	70	5	rad51	rad51	ADJ
biomedich-176	70	6	activity	activity	NOUN
biomedich-176	70	7	,	,	PUNCT
biomedich-176	70	8	brca2	brca2	NOUN
biomedich-176	70	9	smail	smail	NOUN
biomedich-176	70	10	–	–	PUNCT
biomedich-176	70	11	the	the	DET
biomedich-176	70	12	roles	role	NOUN
biomedich-176	70	13	of	of	ADP
biomedich-176	70	14	the	the	DET
biomedich-176	70	15	fluorescent	fluorescent	NOUN
biomedich-176	70	16	in	in	ADP
biomedich-176	70	17	situ	situ	ADJ
biomedich-176	70	18	hybridization	hybridization	NOUN
biomedich-176	70	19	(	(	PUNCT
biomedich-176	70	20	fish	fish	NOUN
biomedich-176	70	21	)	)	PUNCT
biomedich-176	70	22	and	and	CCONJ
biomedich-176	70	23	…	…	PUNCT
biomedich-176	70	24	47	47	NUM
biomedich-176	70	25	has	have	VERB
biomedich-176	70	26	a	a	DET
biomedich-176	70	27	role	role	NOUN
biomedich-176	70	28	.	.	PUNCT
biomedich-176	71	1	rad51	rad51	PROPN
biomedich-176	71	2	is	be	AUX
biomedich-176	71	3	a	a	DET
biomedich-176	71	4	highly	highly	ADV
biomedich-176	71	5	conserved	conserve	VERB
biomedich-176	71	6	dna	dna	NOUN
biomedich-176	71	7	recombinase	recombinase	NOUN
biomedich-176	71	8	involved	involve	VERB
biomedich-176	71	9	in	in	ADP
biomedich-176	71	10	double	double	ADJ
biomedich-176	71	11	-	-	PUNCT
biomedich-176	71	12	strand	strand	NOUN
biomedich-176	71	13	break	break	NOUN
biomedich-176	71	14	repair	repair	NOUN
biomedich-176	71	15	and	and	CCONJ
biomedich-176	71	16	replication	replication	NOUN
biomedich-176	71	17	fork	fork	NOUN
biomedich-176	71	18	arrest	arrest	NOUN
biomedich-176	71	19	(	(	PUNCT
biomedich-176	71	20	da	da	NOUN
biomedich-176	71	21	and	and	CCONJ
biomedich-176	71	22	lakhani	lakhani	NOUN
biomedich-176	71	23	,	,	PUNCT
biomedich-176	71	24	2010	2010	NUM
biomedich-176	71	25	)	)	PUNCT
biomedich-176	71	26	.	.	PUNCT
biomedich-176	72	1	chromosomal	chromosomal	ADJ
biomedich-176	72	2	abnormality	abnormality	NOUN
biomedich-176	72	3	in	in	ADP
biomedich-176	72	4	breast	breast	NOUN
biomedich-176	72	5	cancer	cancer	NOUN
biomedich-176	72	6	the	the	DET
biomedich-176	72	7	most	most	ADV
biomedich-176	72	8	common	common	ADJ
biomedich-176	72	9	cytogenetic	cytogenetic	ADJ
biomedich-176	72	10	anomalies	anomaly	NOUN
biomedich-176	72	11	observed	observe	VERB
biomedich-176	72	12	in	in	ADP
biomedich-176	72	13	human	human	ADJ
biomedich-176	72	14	breast	breast	NOUN
biomedich-176	72	15	carcinoma	carcinoma	NOUN
biomedich-176	72	16	are	be	AUX
biomedich-176	72	17	modifications	modification	NOUN
biomedich-176	72	18	to	to	ADP
biomedich-176	72	19	the	the	DET
biomedich-176	72	20	long	long	ADJ
biomedich-176	72	21	arm	arm	NOUN
biomedich-176	72	22	of	of	ADP
biomedich-176	72	23	chromosome	chromosome	NOUN
biomedich-176	72	24	1	1	NUM
biomedich-176	72	25	(	(	PUNCT
biomedich-176	72	26	bièche	bièche	NOUN
biomedich-176	72	27	and	and	CCONJ
biomedich-176	72	28	lidereau	lidereau	NOUN
biomedich-176	72	29	,	,	PUNCT
biomedich-176	72	30	1995	1995	NUM
biomedich-176	72	31	)	)	PUNCT
biomedich-176	72	32	.	.	PUNCT
biomedich-176	73	1	for	for	ADP
biomedich-176	73	2	four	four	NUM
biomedich-176	73	3	ductal	ductal	ADJ
biomedich-176	73	4	breast	breast	NOUN
biomedich-176	73	5	carcinomas	carcinoma	NOUN
biomedich-176	73	6	,	,	PUNCT
biomedich-176	73	7	the	the	DET
biomedich-176	73	8	cytogenetic	cytogenetic	ADJ
biomedich-176	73	9	analysis	analysis	NOUN
biomedich-176	73	10	showed	show	VERB
biomedich-176	73	11	a	a	DET
biomedich-176	73	12	net	net	ADJ
biomedich-176	73	13	benefit	benefit	NOUN
biomedich-176	73	14	of	of	ADP
biomedich-176	73	15	1	1	NUM
biomedich-176	73	16	q	q	NOUN
biomedich-176	73	17	in	in	ADP
biomedich-176	73	18	all	all	DET
biomedich-176	73	19	tumours	tumour	NOUN
biomedich-176	73	20	.	.	PUNCT
biomedich-176	74	1	the	the	DET
biomedich-176	74	2	only	only	ADJ
biomedich-176	74	3	improvement	improvement	NOUN
biomedich-176	74	4	in	in	ADP
biomedich-176	74	5	the	the	DET
biomedich-176	74	6	first	first	ADJ
biomedich-176	74	7	tumour	tumour	NOUN
biomedich-176	74	8	was	be	AUX
biomedich-176	74	9	that	that	SCONJ
biomedich-176	74	10	one	one	NUM
biomedich-176	74	11	chromosome	chromosome	NOUN
biomedich-176	74	12	16	16	NUM
biomedich-176	74	13	was	be	AUX
biomedich-176	74	14	replaced	replace	VERB
biomedich-176	74	15	by	by	ADP
biomedich-176	74	16	a	a	DET
biomedich-176	74	17	chromosome	chromosome	NOUN
biomedich-176	74	18	derivative	derivative	NOUN
biomedich-176	74	19	consisting	consisting	NOUN
biomedich-176	74	20	of	of	ADP
biomedich-176	74	21	16p	16p	NOUN
biomedich-176	74	22	and	and	CCONJ
biomedich-176	74	23	1q	1q	NUM
biomedich-176	74	24	(	(	PUNCT
biomedich-176	74	25	pandis	pandis	X
biomedich-176	74	26	et	et	PROPN
biomedich-176	74	27	al	al	PROPN
biomedich-176	74	28	.	.	PROPN
biomedich-176	74	29	,	,	PUNCT
biomedich-176	74	30	1992	1992	NUM
biomedich-176	74	31	)	)	PUNCT
biomedich-176	74	32	.	.	PUNCT
biomedich-176	75	1	active	active	ADJ
biomedich-176	75	2	x	x	PUNCT
biomedich-176	75	3	chromosome	chromosome	NOUN
biomedich-176	75	4	duplication	duplication	NOUN
biomedich-176	75	5	and	and	CCONJ
biomedich-176	75	6	xi	xi	ADP
biomedich-176	75	7	loss	loss	NOUN
biomedich-176	75	8	characterized	characterize	VERB
biomedich-176	75	9	almost	almost	ADV
biomedich-176	75	10	half	half	NOUN
biomedich-176	75	11	of	of	ADP
biomedich-176	75	12	the	the	DET
biomedich-176	75	13	cases	case	NOUN
biomedich-176	75	14	of	of	ADP
biomedich-176	75	15	sporadic	sporadic	ADJ
biomedich-176	75	16	basallike	basallike	ADJ
biomedich-176	75	17	cancers	cancer	NOUN
biomedich-176	75	18	studied	study	VERB
biomedich-176	75	19	(	(	PUNCT
biomedich-176	75	20	richardson	richardson	PROPN
biomedich-176	75	21	et	et	PROPN
biomedich-176	75	22	al	al	PROPN
biomedich-176	75	23	.	.	PROPN
biomedich-176	75	24	,	,	PUNCT
biomedich-176	75	25	2006	2006	NUM
biomedich-176	75	26	)	)	PUNCT
biomedich-176	75	27	.	.	PUNCT
biomedich-176	76	1	grade	grade	NOUN
biomedich-176	76	2	i	i	PROPN
biomedich-176	76	3	and	and	CCONJ
biomedich-176	76	4	tubular	tubular	ADJ
biomedich-176	76	5	breast	breast	NOUN
biomedich-176	76	6	carcinomas	carcinoma	NOUN
biomedich-176	76	7	have	have	VERB
biomedich-176	76	8	a	a	DET
biomedich-176	76	9	limited	limited	ADJ
biomedich-176	76	10	number	number	NOUN
biomedich-176	76	11	of	of	ADP
biomedich-176	76	12	genomic	genomic	ADJ
biomedich-176	76	13	alterations	alteration	NOUN
biomedich-176	76	14	with	with	ADP
biomedich-176	76	15	extremely	extremely	ADV
biomedich-176	76	16	recurring	recur	VERB
biomedich-176	76	17	16q	16q	NOUN
biomedich-176	76	18	losses	loss	NOUN
biomedich-176	76	19	,	,	PUNCT
biomedich-176	76	20	while	while	SCONJ
biomedich-176	76	21	grade	grade	NOUN
biomedich-176	76	22	iii	iii	NUM
biomedich-176	76	23	breast	breast	NOUN
biomedich-176	76	24	carcinomas	carcinoma	NOUN
biomedich-176	76	25	also	also	ADV
biomedich-176	76	26	have	have	VERB
biomedich-176	76	27	complex	complex	ADJ
biomedich-176	76	28	genotypes	genotype	NOUN
biomedich-176	76	29	with	with	ADP
biomedich-176	76	30	11q	11q	NOUN
biomedich-176	76	31	,	,	PUNCT
biomedich-176	76	32	14q	14q	NUM
biomedich-176	76	33	,	,	PUNCT
biomedich-176	76	34	8p	8p	NUM
biomedich-176	76	35	,	,	PUNCT
biomedich-176	76	36	13q	13q	NUM
biomedich-176	76	37	loss	loss	NOUN
biomedich-176	76	38	;	;	PUNCT
biomedich-176	76	39	17q	17q	NUM
biomedich-176	76	40	,	,	PUNCT
biomedich-176	76	41	8q	8q	NUM
biomedich-176	76	42	,	,	PUNCT
biomedich-176	76	43	5p	5p	NUM
biomedich-176	76	44	gain	gain	NOUN
biomedich-176	76	45	;	;	PUNCT
biomedich-176	76	46	and	and	CCONJ
biomedich-176	76	47	high	high	ADJ
biomedich-176	76	48	-	-	PUNCT
biomedich-176	76	49	level	level	NOUN
biomedich-176	76	50	gains	gain	NOUN
biomedich-176	76	51	(	(	PUNCT
biomedich-176	76	52	amplification	amplification	NOUN
biomedich-176	76	53	)	)	PUNCT
biomedich-176	76	54	on	on	ADP
biomedich-176	76	55	17q12	17q12	NUM
biomedich-176	76	56	,	,	PUNCT
biomedich-176	76	57	17q2224	17q2224	NUM
biomedich-176	76	58	,	,	PUNCT
biomedich-176	76	59	6q22	6q22	NUM
biomedich-176	76	60	,	,	PUNCT
biomedich-176	76	61	8q22	8q22	NUM
biomedich-176	76	62	,	,	PUNCT
biomedich-176	76	63	11q13	11q13	NUM
biomedich-176	76	64	,	,	PUNCT
biomedich-176	76	65	and	and	CCONJ
biomedich-176	76	66	20q13	20q13	NUM
biomedich-176	76	67	(	(	PUNCT
biomedich-176	76	68	simpson	simpson	PROPN
biomedich-176	76	69	et	et	PROPN
biomedich-176	76	70	al	al	PROPN
biomedich-176	76	71	.	.	PROPN
biomedich-176	76	72	,2005	,2005	PUNCT
biomedich-176	76	73	)	)	PUNCT
biomedich-176	76	74	.	.	PUNCT
biomedich-176	77	1	amplification	amplification	NOUN
biomedich-176	77	2	of	of	ADP
biomedich-176	77	3	chromosome	chromosome	NOUN
biomedich-176	77	4	band	band	NOUN
biomedich-176	77	5	11q13	11q13	NUM
biomedich-176	77	6	protooncogenes	protooncogene	NOUN
biomedich-176	77	7	(	(	PUNCT
biomedich-176	77	8	myc	myc	PROPN
biomedich-176	77	9	,	,	PUNCT
biomedich-176	77	10	erbb2	erbb2	PROPN
biomedich-176	77	11	)	)	PUNCT
biomedich-176	77	12	and	and	CCONJ
biomedich-176	77	13	dna	dna	PROPN
biomedich-176	77	14	;	;	PUNCT
biomedich-176	77	15	tp53	tp53	PROPN
biomedich-176	77	16	mutation	mutation	NOUN
biomedich-176	77	17	;	;	PUNCT
biomedich-176	77	18	and	and	CCONJ
biomedich-176	77	19	loss	loss	NOUN
biomedich-176	77	20	of	of	ADP
biomedich-176	77	21	heterozygosity	heterozygosity	NOUN
biomedich-176	77	22	of	of	ADP
biomedich-176	77	23	chromosome	chromosome	NOUN
biomedich-176	77	24	and	and	CCONJ
biomedich-176	77	25	chromosome	chromosome	VERB
biomedich-176	77	26	arms	arm	NOUN
biomedich-176	77	27	1	1	NUM
biomedich-176	77	28	,	,	PUNCT
biomedich-176	77	29	3p	3p	NUM
biomedich-176	77	30	,	,	PUNCT
biomedich-176	77	31	6q	6q	NUM
biomedich-176	77	32	,	,	PUNCT
biomedich-176	77	33	7q	7q	NOUN
biomedich-176	77	34	,	,	PUNCT
biomedich-176	77	35	8p	8p	NUM
biomedich-176	77	36	,	,	PUNCT
biomedich-176	77	37	11	11	NUM
biomedich-176	77	38	,	,	PUNCT
biomedich-176	77	39	13q,16q	13q,16q	NUM
biomedich-176	77	40	,	,	PUNCT
biomedich-176	77	41	17	17	NUM
biomedich-176	77	42	,	,	PUNCT
biomedich-176	77	43	18q	18q	NUM
biomedich-176	77	44	,	,	PUNCT
biomedich-176	77	45	and	and	CCONJ
biomedich-176	77	46	22q	22q	NOUN
biomedich-176	77	47	are	be	AUX
biomedich-176	77	48	the	the	DET
biomedich-176	77	49	main	main	ADJ
biomedich-176	77	50	forms	form	NOUN
biomedich-176	77	51	of	of	ADP
biomedich-176	77	52	genetic	genetic	ADJ
biomedich-176	77	53	defects	defect	NOUN
biomedich-176	77	54	commonly	commonly	ADV
biomedich-176	77	55	found	find	VERB
biomedich-176	77	56	in	in	ADP
biomedich-176	77	57	breast	breast	NOUN
biomedich-176	77	58	tumours	tumour	NOUN
biomedich-176	77	59	(	(	PUNCT
biomedich-176	77	60	bièche	bièche	NOUN
biomedich-176	77	61	et	et	PROPN
biomedich-176	77	62	al	al	PROPN
biomedich-176	77	63	.	.	PROPN
biomedich-176	77	64	,1995	,1995	PUNCT
biomedich-176	77	65	)	)	PUNCT
biomedich-176	77	66	.	.	PUNCT
biomedich-176	78	1	in	in	ADP
biomedich-176	78	2	breast	breast	NOUN
biomedich-176	78	3	cancer	cancer	NOUN
biomedich-176	78	4	,	,	PUNCT
biomedich-176	78	5	abnormalities	abnormality	NOUN
biomedich-176	78	6	of	of	ADP
biomedich-176	78	7	chromosome	chromosome	NOUN
biomedich-176	78	8	17	17	NUM
biomedich-176	78	9	,	,	PUNCT
biomedich-176	78	10	recognized	recognize	VERB
biomedich-176	78	11	over	over	ADP
biomedich-176	78	12	two	two	NUM
biomedich-176	78	13	decades	decade	NOUN
biomedich-176	78	14	ago	ago	ADV
biomedich-176	78	15	to	to	PART
biomedich-176	78	16	be	be	AUX
biomedich-176	78	17	important	important	ADJ
biomedich-176	78	18	in	in	ADP
biomedich-176	78	19	tumorigenesis	tumorigenesis	NOUN
biomedich-176	78	20	,	,	PUNCT
biomedich-176	78	21	frequently	frequently	ADV
biomedich-176	78	22	occur	occur	VERB
biomedich-176	78	23	.	.	PUNCT
biomedich-176	79	1	changes	change	NOUN
biomedich-176	79	2	in	in	ADP
biomedich-176	79	3	unique	unique	ADJ
biomedich-176	79	4	chromosome	chromosome	NOUN
biomedich-176	79	5	17	17	NUM
biomedich-176	79	6	loci	locus	NOUN
biomedich-176	79	7	,	,	PUNCT
biomedich-176	79	8	including	include	VERB
biomedich-176	79	9	amplification	amplification	NOUN
biomedich-176	79	10	of	of	ADP
biomedich-176	79	11	erbb2	erbb2	PROPN
biomedich-176	79	12	,	,	PUNCT
biomedich-176	79	13	loss	loss	NOUN
biomedich-176	79	14	of	of	ADP
biomedich-176	79	15	p53	p53	NOUN
biomedich-176	79	16	,	,	PUNCT
biomedich-176	79	17	loss	loss	NOUN
biomedich-176	79	18	of	of	ADP
biomedich-176	79	19	brca1	brca1	PROPN
biomedich-176	79	20	,	,	PUNCT
biomedich-176	79	21	and	and	CCONJ
biomedich-176	79	22	amplification	amplification	NOUN
biomedich-176	79	23	or	or	CCONJ
biomedich-176	79	24	deletion	deletion	NOUN
biomedich-176	79	25	of	of	ADP
biomedich-176	79	26	top2a	top2a	PROPN
biomedich-176	79	27	,	,	PUNCT
biomedich-176	79	28	are	be	AUX
biomedich-176	79	29	considered	consider	VERB
biomedich-176	79	30	to	to	PART
biomedich-176	79	31	play	play	VERB
biomedich-176	79	32	an	an	DET
biomedich-176	79	33	important	important	ADJ
biomedich-176	79	34	role	role	NOUN
biomedich-176	79	35	in	in	ADP
biomedich-176	79	36	breast	breast	NOUN
biomedich-176	79	37	cancer	cancer	NOUN
biomedich-176	79	38	pathophysiology	pathophysiology	NOUN
biomedich-176	79	39	(	(	PUNCT
biomedich-176	79	40	reinholz	reinholz	PROPN
biomedich-176	79	41	et	et	PROPN
biomedich-176	79	42	al	al	PROPN
biomedich-176	79	43	.	.	PROPN
biomedich-176	79	44	,	,	PUNCT
biomedich-176	79	45	2009	2009	NUM
biomedich-176	79	46	)	)	PUNCT
biomedich-176	79	47	.	.	PUNCT
biomedich-176	80	1	a	a	DET
biomedich-176	80	2	single	single	ADJ
biomedich-176	80	3	amplicon	amplicon	NOUN
biomedich-176	80	4	spanning	span	VERB
biomedich-176	80	5	several	several	ADJ
biomedich-176	80	6	megabases	megabase	NOUN
biomedich-176	80	7	was	be	AUX
biomedich-176	80	8	originally	originally	ADV
biomedich-176	80	9	thought	think	VERB
biomedich-176	80	10	to	to	PART
biomedich-176	80	11	include	include	VERB
biomedich-176	80	12	11q13	11q13	NUM
biomedich-176	80	13	amplification	amplification	NOUN
biomedich-176	80	14	.	.	PUNCT
biomedich-176	81	1	still	still	ADV
biomedich-176	81	2	,	,	PUNCT
biomedich-176	81	3	more	more	ADV
biomedich-176	81	4	recent	recent	ADJ
biomedich-176	81	5	data	datum	NOUN
biomedich-176	81	6	identified	identify	VERB
biomedich-176	81	7	four	four	NUM
biomedich-176	81	8	core	core	NOUN
biomedich-176	81	9	regions	region	NOUN
biomedich-176	81	10	within	within	ADP
biomedich-176	81	11	11q13	11q13	NUM
biomedich-176	81	12	that	that	PRON
biomedich-176	81	13	can	can	AUX
biomedich-176	81	14	be	be	AUX
biomedich-176	81	15	amplified	amplify	VERB
biomedich-176	81	16	separately	separately	ADV
biomedich-176	81	17	or	or	CCONJ
biomedich-176	81	18	separately	separately	ADV
biomedich-176	81	19	together	together	ADV
biomedich-176	81	20	in	in	ADP
biomedich-176	81	21	various	various	ADJ
biomedich-176	81	22	combinations	combination	NOUN
biomedich-176	81	23	(	(	PUNCT
biomedich-176	81	24	ormandy	ormandy	ADJ
biomedich-176	81	25	,	,	PUNCT
biomedich-176	81	26	2003	2003	NUM
biomedich-176	81	27	)	)	PUNCT
biomedich-176	81	28	.	.	PUNCT
biomedich-176	82	1	chromosomal	chromosomal	ADJ
biomedich-176	82	2	alterations	alteration	NOUN
biomedich-176	82	3	can	can	AUX
biomedich-176	82	4	be	be	AUX
biomedich-176	82	5	tested	test	VERB
biomedich-176	82	6	using	use	VERB
biomedich-176	82	7	gbanding	gbande	VERB
biomedich-176	82	8	karyotype	karyotype	NOUN
biomedich-176	82	9	and	and	CCONJ
biomedich-176	82	10	multicolour	multicolour	ADJ
biomedich-176	82	11	fluorescence	fluorescence	NOUN
biomedich-176	82	12	in	in	ADP
biomedich-176	82	13	situ	situ	ADJ
biomedich-176	82	14	hybridization	hybridization	NOUN
biomedich-176	82	15	(	(	PUNCT
biomedich-176	82	16	m	m	NOUN
biomedich-176	82	17	-	-	NOUN
biomedich-176	82	18	fish	fish	NOUN
biomedich-176	82	19	)	)	PUNCT
biomedich-176	82	20	on	on	ADP
biomedich-176	82	21	metaphases	metaphase	NOUN
biomedich-176	82	22	(	(	PUNCT
biomedich-176	82	23	rondón	rondón	X
biomedich-176	82	24	et	et	PROPN
biomedich-176	82	25	al	al	PROPN
biomedich-176	82	26	.	.	PROPN
biomedich-176	82	27	,2014	,2014	PROPN
biomedich-176	82	28	)	)	PUNCT
biomedich-176	82	29	.	.	PUNCT
biomedich-176	83	1	fluorescence	fluorescence	NOUN
biomedich-176	83	2	in	in	ADP
biomedich-176	83	3	situ	situ	ADJ
biomedich-176	83	4	hybridization	hybridization	NOUN
biomedich-176	83	5	(	(	PUNCT
biomedich-176	83	6	fish	fish	NOUN
biomedich-176	83	7	)	)	PUNCT
biomedich-176	83	8	allows	allow	VERB
biomedich-176	83	9	the	the	DET
biomedich-176	83	10	number	number	NOUN
biomedich-176	83	11	of	of	ADP
biomedich-176	83	12	the	the	DET
biomedich-176	83	13	gene	gene	NOUN
biomedich-176	83	14	or	or	CCONJ
biomedich-176	83	15	chromosome	chromosome	NOUN
biomedich-176	83	16	copies	copy	NOUN
biomedich-176	83	17	in	in	ADP
biomedich-176	83	18	archival	archival	NOUN
biomedich-176	83	19	tissues	tissue	NOUN
biomedich-176	83	20	to	to	PART
biomedich-176	83	21	be	be	AUX
biomedich-176	83	22	measured	measure	VERB
biomedich-176	83	23	in	in	ADP
biomedich-176	83	24	situ	situ	NOUN
biomedich-176	83	25	and	and	CCONJ
biomedich-176	83	26	linked	link	VERB
biomedich-176	83	27	to	to	ADP
biomedich-176	83	28	morphology	morphology	NOUN
biomedich-176	83	29	and	and	CCONJ
biomedich-176	83	30	clinical	clinical	ADJ
biomedich-176	83	31	outcome	outcome	NOUN
biomedich-176	83	32	(	(	PUNCT
biomedich-176	83	33	watters	watter	NOUN
biomedich-176	83	34	et	et	PROPN
biomedich-176	83	35	al	al	PROPN
biomedich-176	83	36	.	.	PROPN
biomedich-176	83	37	,	,	PUNCT
biomedich-176	83	38	2003	2003	NUM
biomedich-176	83	39	)	)	PUNCT
biomedich-176	83	40	.	.	PUNCT
biomedich-176	84	1	for	for	ADP
biomedich-176	84	2	example	example	NOUN
biomedich-176	84	3	,	,	PUNCT
biomedich-176	84	4	cytokinetic	cytokinetic	ADJ
biomedich-176	84	5	defects	defect	NOUN
biomedich-176	84	6	are	be	AUX
biomedich-176	84	7	characterized	characterize	VERB
biomedich-176	84	8	by	by	ADP
biomedich-176	84	9	chromosomal	chromosomal	ADJ
biomedich-176	84	10	instability	instability	NOUN
biomedich-176	84	11	in	in	ADP
biomedich-176	84	12	an	an	DET
biomedich-176	84	13	inherited	inherit	VERB
biomedich-176	84	14	cancer	cancer	NOUN
biomedich-176	84	15	syndrome	syndrome	NOUN
biomedich-176	84	16	and	and	CCONJ
biomedich-176	84	17	may	may	AUX
biomedich-176	84	18	help	help	VERB
biomedich-176	84	19	explain	explain	VERB
biomedich-176	84	20	why	why	SCONJ
biomedich-176	84	21	brca2	brca2	NOUN
biomedich-176	84	22	-	-	PUNCT
biomedich-176	84	23	deficient	deficient	ADJ
biomedich-176	84	24	tumours	tumour	NOUN
biomedich-176	84	25	are	be	AUX
biomedich-176	84	26	also	also	ADV
biomedich-176	84	27	aneuploidy	aneuploidy	ADJ
biomedich-176	84	28	-	-	PUNCT
biomedich-176	84	29	deficient	deficient	ADJ
biomedich-176	84	30	(	(	PUNCT
biomedich-176	84	31	daniels	daniels	PROPN
biomedich-176	84	32	et	et	PROPN
biomedich-176	84	33	al	al	PROPN
biomedich-176	84	34	.	.	PROPN
biomedich-176	84	35	,	,	PUNCT
biomedich-176	84	36	2004	2004	NUM
biomedich-176	84	37	)	)	PUNCT
biomedich-176	84	38	.	.	PUNCT
biomedich-176	85	1	the	the	DET
biomedich-176	85	2	innovation	innovation	NOUN
biomedich-176	85	3	is	be	AUX
biomedich-176	85	4	known	know	VERB
biomedich-176	85	5	as	as	ADP
biomedich-176	85	6	comparative	comparative	ADJ
biomedich-176	85	7	genomic	genomic	NOUN
biomedich-176	85	8	hybridization	hybridization	NOUN
biomedich-176	85	9	(	(	PUNCT
biomedich-176	85	10	cgh	cgh	PROPN
biomedich-176	85	11	)	)	PUNCT
biomedich-176	85	12	,	,	PUNCT
biomedich-176	85	13	sets	set	VERB
biomedich-176	85	14	out	out	ADP
biomedich-176	85	15	methods	method	NOUN
biomedich-176	85	16	for	for	ADP
biomedich-176	85	17	evaluating	evaluate	VERB
biomedich-176	85	18	the	the	DET
biomedich-176	85	19	relative	relative	ADJ
biomedich-176	85	20	number	number	NOUN
biomedich-176	85	21	of	of	ADP
biomedich-176	85	22	copies	copy	NOUN
biomedich-176	85	23	of	of	ADP
biomedich-176	85	24	nucleic	nucleic	ADJ
biomedich-176	85	25	acid	acid	NOUN
biomedich-176	85	26	sequences	sequence	NOUN
biomedich-176	85	27	in	in	ADP
biomedich-176	85	28	or	or	CCONJ
biomedich-176	85	29	in	in	ADP
biomedich-176	85	30	parts	part	NOUN
biomedich-176	85	31	of	of	ADP
biomedich-176	85	32	one	one	NUM
biomedich-176	85	33	or	or	CCONJ
biomedich-176	85	34	more	more	ADJ
biomedich-176	85	35	subject	subject	ADJ
biomedich-176	85	36	genomes	genome	NOUN
biomedich-176	85	37	(	(	PUNCT
biomedich-176	85	38	e.g.	e.g.	ADV
biomedich-176	85	39	a	a	DET
biomedich-176	85	40	tumour	tumour	NOUN
biomedich-176	85	41	cell	cell	NOUN
biomedich-176	85	42	)	)	PUNCT
biomedich-176	85	43	as	as	ADP
biomedich-176	85	44	a	a	DET
biomedich-176	85	45	function	function	NOUN
biomedich-176	85	46	of	of	ADP
biomedich-176	85	47	the	the	DET
biomedich-176	85	48	position	position	NOUN
biomedich-176	85	49	of	of	ADP
biomedich-176	85	50	certain	certain	ADJ
biomedich-176	85	51	sequences	sequence	NOUN
biomedich-176	85	52	in	in	ADP
biomedich-176	85	53	the	the	DET
biomedich-176	85	54	reference	reference	NOUN
biomedich-176	85	55	genome	genome	NOUN
biomedich-176	85	56	(	(	PUNCT
biomedich-176	85	57	e.g.	e.g.	ADV
biomedich-176	85	58	a	a	DET
biomedich-176	85	59	regular	regular	ADJ
biomedich-176	85	60	human	human	ADJ
biomedich-176	85	61	genome	genome	NOUN
biomedich-176	85	62	)	)	PUNCT
biomedich-176	85	63	(	(	PUNCT
biomedich-176	85	64	pinkel	pinkel	NOUN
biomedich-176	85	65	et	et	PROPN
biomedich-176	85	66	al	al	PROPN
biomedich-176	85	67	.	.	PROPN
biomedich-176	85	68	,	,	PUNCT
biomedich-176	85	69	2011	2011	NUM
biomedich-176	85	70	)	)	PUNCT
biomedich-176	85	71	.	.	PUNCT
biomedich-176	86	1	initial	initial	ADJ
biomedich-176	86	2	cgh	cgh	PROPN
biomedich-176	86	3	array	array	VERB
biomedich-176	86	4	applications	application	NOUN
biomedich-176	86	5	for	for	ADP
biomedich-176	86	6	breast	breast	NOUN
biomedich-176	86	7	cancer	cancer	NOUN
biomedich-176	86	8	analysis	analysis	NOUN
biomedich-176	86	9	and	and	CCONJ
biomedich-176	86	10	the	the	DET
biomedich-176	86	11	mechanisms	mechanism	NOUN
biomedich-176	86	12	by	by	ADP
biomedich-176	86	13	which	which	PRON
biomedich-176	86	14	various	various	ADJ
biomedich-176	86	15	types	type	NOUN
biomedich-176	86	16	of	of	ADP
biomedich-176	86	17	copy	copy	NOUN
biomedich-176	86	18	number	number	NOUN
biomedich-176	86	19	changes	change	NOUN
biomedich-176	86	20	can	can	AUX
biomedich-176	86	21	occur	occur	VERB
biomedich-176	86	22	have	have	AUX
biomedich-176	86	23	been	be	AUX
biomedich-176	86	24	described	describe	VERB
biomedich-176	86	25	(	(	PUNCT
biomedich-176	86	26	albertson	albertson	NOUN
biomedich-176	86	27	2003	2003	NUM
biomedich-176	86	28	)	)	PUNCT
biomedich-176	86	29	.	.	PUNCT
biomedich-176	87	1	how	how	SCONJ
biomedich-176	87	2	does	do	AUX
biomedich-176	87	3	fluorescence	fluorescence	NOUN
biomedich-176	87	4	in	in	ADP
biomedich-176	87	5	situ	situ	ADJ
biomedich-176	87	6	hybridization	hybridization	NOUN
biomedich-176	87	7	works	work	NOUN
biomedich-176	87	8	?	?	PUNCT
biomedich-176	88	1	fluorescence	fluorescence	NOUN
biomedich-176	88	2	in	in	ADP
biomedich-176	88	3	situ	situ	ADJ
biomedich-176	88	4	hybridization	hybridization	NOUN
biomedich-176	88	5	by	by	ADP
biomedich-176	88	6	a	a	DET
biomedich-176	88	7	fluorescently	fluorescently	ADV
biomedich-176	88	8	labelled	label	VERB
biomedich-176	88	9	probe	probe	NOUN
biomedich-176	88	10	detects	detect	NOUN
biomedich-176	88	11	nucleic	nucleic	ADJ
biomedich-176	88	12	acid	acid	NOUN
biomedich-176	88	13	sequences	sequence	NOUN
biomedich-176	88	14	that	that	PRON
biomedich-176	88	15	precisely	precisely	ADV
biomedich-176	88	16	hybridize	hybridize	ADJ
biomedich-176	88	17	within	within	ADP
biomedich-176	88	18	the	the	DET
biomedich-176	88	19	intact	intact	ADJ
biomedich-176	88	20	cell	cell	NOUN
biomedich-176	88	21	to	to	ADP
biomedich-176	88	22	its	its	PRON
biomedich-176	88	23	complementary	complementary	ADJ
biomedich-176	88	24	target	target	NOUN
biomedich-176	88	25	sequence	sequence	NOUN
biomedich-176	88	26	(	(	PUNCT
biomedich-176	88	27	moter	moter	NOUN
biomedich-176	88	28	and	and	CCONJ
biomedich-176	88	29	göbel	göbel	NOUN
biomedich-176	88	30	,	,	PUNCT
biomedich-176	88	31	2000	2000	NUM
biomedich-176	88	32	)	)	PUNCT
biomedich-176	88	33	.	.	PUNCT
biomedich-176	89	1	fluorescence	fluorescence	NOUN
biomedich-176	89	2	in	in	ADP
biomedich-176	89	3	situ	situ	ADJ
biomedich-176	89	4	hybridization	hybridization	NOUN
biomedich-176	89	5	has	have	AUX
biomedich-176	89	6	been	be	AUX
biomedich-176	89	7	used	use	VERB
biomedich-176	89	8	in	in	ADP
biomedich-176	89	9	interphase	interphase	ADJ
biomedich-176	89	10	nuclei	nucleus	NOUN
biomedich-176	89	11	to	to	ADP
biomedich-176	89	12	image	image	NOUN
biomedich-176	89	13	complex	complex	ADJ
biomedich-176	89	14	genomic	genomic	ADJ
biomedich-176	89	15	dna	dna	NOUN
biomedich-176	89	16	sequences	sequence	NOUN
biomedich-176	89	17	.	.	PUNCT
biomedich-176	90	1	unreplicated	unreplicate	VERB
biomedich-176	90	2	dna	dna	PROPN
biomedich-176	90	3	parts	part	NOUN
biomedich-176	90	4	give	give	VERB
biomedich-176	90	5	singlet	singlet	ADJ
biomedich-176	90	6	hybridization	hybridization	NOUN
biomedich-176	90	7	signals	signal	NOUN
biomedich-176	90	8	in	in	ADP
biomedich-176	90	9	normal	normal	ADJ
biomedich-176	90	10	diploid	diploid	ADJ
biomedich-176	90	11	cells	cell	NOUN
biomedich-176	90	12	,	,	PUNCT
biomedich-176	90	13	whereas	whereas	SCONJ
biomedich-176	90	14	replicated	replicate	VERB
biomedich-176	90	15	loci	locus	NOUN
biomedich-176	90	16	are	be	AUX
biomedich-176	90	17	characterized	characterize	VERB
biomedich-176	90	18	by	by	ADP
biomedich-176	90	19	doublets	doublet	NOUN
biomedich-176	90	20	(	(	PUNCT
biomedich-176	90	21	selig	selig	PROPN
biomedich-176	90	22	et	et	PROPN
biomedich-176	90	23	al	al	PROPN
biomedich-176	90	24	.	.	PROPN
biomedich-176	90	25	,	,	PUNCT
biomedich-176	90	26	1992	1992	NUM
biomedich-176	90	27	)	)	PUNCT
biomedich-176	90	28	.	.	PUNCT
biomedich-176	91	1	fish	fish	NOUN
biomedich-176	91	2	on	on	ADP
biomedich-176	91	3	3d	3d	NUM
biomedich-176	91	4	preserved	preserve	VERB
biomedich-176	91	5	nuclei	nucleus	NOUN
biomedich-176	91	6	,	,	PUNCT
biomedich-176	91	7	compared	compare	VERB
biomedich-176	91	8	to	to	PART
biomedich-176	91	9	fish	fish	VERB
biomedich-176	91	10	on	on	ADP
biomedich-176	91	11	metaphase	metaphase	ADJ
biomedich-176	91	12	chromosomes	chromosome	NOUN
biomedich-176	91	13	and	and	CCONJ
biomedich-176	91	14	traditional	traditional	ADJ
biomedich-176	91	15	interphase	interphase	NOUN
biomedich-176	91	16	cytogenetics	cytogenetic	NOUN
biomedich-176	91	17	,	,	PUNCT
biomedich-176	91	18	needs	need	VERB
biomedich-176	91	19	special	special	ADJ
biomedich-176	91	20	requirements	requirement	NOUN
biomedich-176	91	21	concerning	concern	VERB
biomedich-176	91	22	the	the	DET
biomedich-176	91	23	consistency	consistency	NOUN
biomedich-176	91	24	of	of	ADP
biomedich-176	91	25	the	the	DET
biomedich-176	91	26	probe	probe	NOUN
biomedich-176	91	27	,	,	PUNCT
biomedich-176	91	28	fixation	fixation	NOUN
biomedich-176	91	29	,	,	PUNCT
biomedich-176	91	30	and	and	CCONJ
biomedich-176	91	31	pretreatment	pretreatment	NOUN
biomedich-176	91	32	steps	step	NOUN
biomedich-176	91	33	of	of	ADP
biomedich-176	91	34	the	the	DET
biomedich-176	91	35	cells	cell	NOUN
biomedich-176	91	36	to	to	PART
biomedich-176	91	37	achieve	achieve	VERB
biomedich-176	91	38	the	the	DET
biomedich-176	91	39	two	two	NUM
biomedich-176	91	40	objectives	objective	NOUN
biomedich-176	91	41	,	,	PUNCT
biomedich-176	91	42	namely	namely	ADV
biomedich-176	91	43	the	the	DET
biomedich-176	91	44	best	good	ADJ
biomedich-176	91	45	possible	possible	ADJ
biomedich-176	91	46	preservation	preservation	NOUN
biomedich-176	91	47	of	of	ADP
biomedich-176	91	48	the	the	DET
biomedich-176	91	49	nuclear	nuclear	ADJ
biomedich-176	91	50	structure	structure	NOUN
biomedich-176	91	51	and	and	CCONJ
biomedich-176	91	52	at	at	ADP
biomedich-176	91	53	the	the	DET
biomedich-176	91	54	same	same	ADJ
biomedich-176	91	55	time	time	NOUN
biomedich-176	91	56	,	,	PUNCT
biomedich-176	91	57	the	the	DET
biomedich-176	91	58	efficient	efficient	ADJ
biomedich-176	91	59	accessibility	accessibility	NOUN
biomedich-176	91	60	of	of	ADP
biomedich-176	91	61	the	the	DET
biomedich-176	91	62	probe	probe	NOUN
biomedich-176	91	63	(	(	PUNCT
biomedich-176	91	64	cremer	cremer	PROPN
biomedich-176	91	65	et	et	PROPN
biomedich-176	91	66	al	al	PROPN
biomedich-176	91	67	.	.	PROPN
biomedich-176	91	68	,2012	,2012	PROPN
biomedich-176	91	69	)	)	PUNCT
biomedich-176	91	70	.	.	PUNCT
biomedich-176	92	1	the	the	DET
biomedich-176	92	2	concepts	concept	NOUN
biomedich-176	92	3	of	of	ADP
biomedich-176	92	4	in	in	ADP
biomedich-176	92	5	situ	situ	ADJ
biomedich-176	92	6	hybridizations	hybridization	NOUN
biomedich-176	92	7	of	of	ADP
biomedich-176	92	8	fluorescence	fluorescence	NOUN
biomedich-176	92	9	are	be	AUX
biomedich-176	92	10	as	as	SCONJ
biomedich-176	92	11	follows	follow	VERB
biomedich-176	92	12	:	:	PUNCT
biomedich-176	92	13	(	(	PUNCT
biomedich-176	92	14	a	a	X
biomedich-176	92	15	)	)	PUNCT
biomedich-176	92	16	dna	dna	NOUN
biomedich-176	92	17	probe	probe	NOUN
biomedich-176	92	18	and	and	CCONJ
biomedich-176	92	19	a	a	DET
biomedich-176	92	20	target	target	NOUN
biomedich-176	92	21	sequence	sequence	NOUN
biomedich-176	92	22	are	be	AUX
biomedich-176	92	23	the	the	DET
biomedich-176	92	24	basic	basic	ADJ
biomedich-176	92	25	elements	element	NOUN
biomedich-176	92	26	.	.	PUNCT
biomedich-176	93	1	(	(	PUNCT
biomedich-176	93	2	b	b	X
biomedich-176	93	3	)	)	PUNCT
biomedich-176	93	4	before	before	ADP
biomedich-176	93	5	hybridization	hybridization	NOUN
biomedich-176	93	6	,	,	PUNCT
biomedich-176	93	7	the	the	DET
biomedich-176	93	8	dna	dna	PROPN
biomedich-176	93	9	probe	probe	NOUN
biomedich-176	93	10	is	be	AUX
biomedich-176	93	11	indirectly	indirectly	ADV
biomedich-176	93	12	marked	mark	VERB
biomedich-176	93	13	with	with	ADP
biomedich-176	93	14	a	a	DET
biomedich-176	93	15	hapten	hapten	VERB
biomedich-176	93	16	,	,	PUNCT
biomedich-176	93	17	specifically	specifically	ADV
biomedich-176	93	18	marked	mark	VERB
biomedich-176	93	19	with	with	ADP
biomedich-176	93	20	hapten	hapten	VERB
biomedich-176	93	21	by	by	ADP
biomedich-176	93	22	adding	add	VERB
biomedich-176	93	23	a	a	DET
biomedich-176	93	24	fluorophore	fluorophore	NOUN
biomedich-176	93	25	probe	probe	NOUN
biomedich-176	93	26	(	(	PUNCT
biomedich-176	93	27	right	right	ADJ
biomedich-176	93	28	panel	panel	NOUN
biomedich-176	93	29	)	)	PUNCT
biomedich-176	93	30	.	.	PUNCT
biomedich-176	94	1	(	(	PUNCT
biomedich-176	94	2	c	c	X
biomedich-176	94	3	)	)	PUNCT
biomedich-176	94	4	the	the	DET
biomedich-176	94	5	labelled	label	VERB
biomedich-176	94	6	probe	probe	NOUN
biomedich-176	94	7	and	and	CCONJ
biomedich-176	94	8	the	the	DET
biomedich-176	94	9	target	target	NOUN
biomedich-176	94	10	dna	dna	NOUN
biomedich-176	94	11	are	be	AUX
biomedich-176	94	12	denatured	denature	VERB
biomedich-176	94	13	to	to	PART
biomedich-176	94	14	yield	yield	VERB
biomedich-176	94	15	single	single	ADJ
biomedich-176	94	16	-	-	PUNCT
biomedich-176	94	17	stranded	strand	VERB
biomedich-176	94	18	dna	dna	NOUN
biomedich-176	94	19	.	.	PUNCT
biomedich-176	95	1	(	(	PUNCT
biomedich-176	95	2	d	d	X
biomedich-176	95	3	)	)	PUNCT
biomedich-176	95	4	then	then	ADV
biomedich-176	95	5	they	they	PRON
biomedich-176	95	6	are	be	AUX
biomedich-176	95	7	combined	combine	VERB
biomedich-176	95	8	,	,	PUNCT
biomedich-176	95	9	which	which	PRON
biomedich-176	95	10	allows	allow	VERB
biomedich-176	95	11	complementary	complementary	ADJ
biomedich-176	95	12	dna	dna	PROPN
biomedich-176	95	13	sequences	sequence	NOUN
biomedich-176	95	14	to	to	PART
biomedich-176	95	15	be	be	AUX
biomedich-176	95	16	annealed	anneal	VERB
biomedich-176	95	17	.	.	PUNCT
biomedich-176	96	1	(	(	PUNCT
biomedich-176	96	2	e	e	X
biomedich-176	96	3	)	)	PUNCT
biomedich-176	96	4	if	if	SCONJ
biomedich-176	96	5	the	the	DET
biomedich-176	96	6	probe	probe	NOUN
biomedich-176	96	7	has	have	AUX
biomedich-176	96	8	been	be	AUX
biomedich-176	96	9	indirectly	indirectly	ADV
biomedich-176	96	10	labelled	label	VERB
biomedich-176	96	11	,	,	PUNCT
biomedich-176	96	12	the	the	DET
biomedich-176	96	13	visualization	visualization	NOUN
biomedich-176	96	14	of	of	ADP
biomedich-176	96	15	the	the	DET
biomedich-176	96	16	non	non	ADJ
biomedich-176	96	17	-	-	ADJ
biomedich-176	96	18	fluorescent	fluorescent	ADJ
biomedich-176	96	19	hapten	hapten	NOUN
biomedich-176	96	20	using	use	VERB
biomedich-176	96	21	an	an	DET
biomedich-176	96	22	enzymatic	enzymatic	ADJ
biomedich-176	96	23	or	or	CCONJ
biomedich-176	96	24	immunological	immunological	ADJ
biomedich-176	96	25	detection	detection	NOUN
biomedich-176	96	26	system	system	NOUN
biomedich-176	96	27	involves	involve	VERB
biomedich-176	96	28	an	an	DET
biomedich-176	96	29	additional	additional	ADJ
biomedich-176	96	30	step	step	NOUN
biomedich-176	96	31	.	.	PUNCT
biomedich-176	97	1	finally	finally	ADV
biomedich-176	97	2	,	,	PUNCT
biomedich-176	97	3	fluorescence	fluorescence	NOUN
biomedich-176	97	4	microscopy	microscopy	NOUN
biomedich-176	97	5	tests	test	VERB
biomedich-176	97	6	the	the	DET
biomedich-176	97	7	signals	signal	NOUN
biomedich-176	97	8	.	.	PUNCT
biomedich-176	98	1	speicher	speicher	NOUN
biomedich-176	98	2	and	and	CCONJ
biomedich-176	98	3	carte	carte	NOUN
biomedich-176	98	4	adapted	adapt	VERB
biomedich-176	98	5	from	from	ADP
biomedich-176	98	6	(	(	PUNCT
biomedich-176	98	7	speicher	speicher	PROPN
biomedich-176	98	8	et	et	PROPN
biomedich-176	98	9	al	al	PROPN
biomedich-176	98	10	.	.	PROPN
biomedich-176	98	11	,2005	,2005	PUNCT
biomedich-176	98	12	and	and	CCONJ
biomedich-176	98	13	bishop	bishop	PROPN
biomedich-176	98	14	,	,	PUNCT
biomedich-176	98	15	2010	2010	NUM
biomedich-176	98	16	)	)	PUNCT
biomedich-176	98	17	.	.	PUNCT
biomedich-176	99	1	hapten	hapten	VERB
biomedich-176	99	2	binding	bind	VERB
biomedich-176	99	3	is	be	AUX
biomedich-176	99	4	visualized	visualize	VERB
biomedich-176	99	5	using	use	VERB
biomedich-176	99	6	a	a	DET
biomedich-176	99	7	subsequently	subsequently	ADV
biomedich-176	99	8	applied	apply	VERB
biomedich-176	99	9	fluorochromeconjugated	fluorochromeconjugated	ADJ
biomedich-176	99	10	antibody	antibody	NOUN
biomedich-176	99	11	(	(	PUNCT
biomedich-176	99	12	waminal	waminal	ADJ
biomedich-176	99	13	et	et	PROPN
biomedich-176	99	14	al	al	PROPN
biomedich-176	99	15	.	.	PROPN
biomedich-176	99	16	,2018	,2018	PROPN
biomedich-176	99	17	)	)	PUNCT
biomedich-176	99	18	.	.	PUNCT
biomedich-176	100	1	the	the	DET
biomedich-176	100	2	choice	choice	NOUN
biomedich-176	100	3	of	of	ADP
biomedich-176	100	4	the	the	DET
biomedich-176	100	5	probe	probe	NOUN
biomedich-176	100	6	is	be	AUX
biomedich-176	100	7	one	one	NUM
biomedich-176	100	8	of	of	ADP
biomedich-176	100	9	the	the	DET
biomedich-176	100	10	most	most	ADV
biomedich-176	100	11	significant	significant	ADJ
biomedich-176	100	12	factors	factor	NOUN
biomedich-176	100	13	in	in	ADP
biomedich-176	100	14	fish	fish	NOUN
biomedich-176	100	15	research	research	NOUN
biomedich-176	100	16	.	.	PUNCT
biomedich-176	101	1	it	it	PRON
biomedich-176	101	2	is	be	AUX
biomedich-176	101	3	possible	possible	ADJ
biomedich-176	101	4	to	to	PART
biomedich-176	101	5	use	use	VERB
biomedich-176	101	6	a	a	DET
biomedich-176	101	7	large	large	ADJ
biomedich-176	101	8	variety	variety	NOUN
biomedich-176	101	9	of	of	ADP
biomedich-176	101	10	probes	probe	NOUN
biomedich-176	101	11	,	,	PUNCT
biomedich-176	101	12	from	from	ADP
biomedich-176	101	13	whole	whole	ADJ
biomedich-176	101	14	genomes	genome	NOUN
biomedich-176	101	15	to	to	ADP
biomedich-176	101	16	tiny	tiny	ADJ
biomedich-176	101	17	cloned	cloned	ADJ
biomedich-176	101	18	probes	probe	NOUN
biomedich-176	101	19	(	(	PUNCT
biomedich-176	101	20	1–10	1–10	PROPN
biomedich-176	101	21	kb	kb	PROPN
biomedich-176	101	22	)	)	PUNCT
biomedich-176	101	23	.	.	PUNCT
biomedich-176	102	1	there	there	PRON
biomedich-176	102	2	are	be	VERB
biomedich-176	102	3	three	three	NUM
biomedich-176	102	4	types	type	NOUN
biomedich-176	102	5	of	of	ADP
biomedich-176	102	6	probes	probe	NOUN
biomedich-176	102	7	in	in	ADP
biomedich-176	102	8	general	general	ADJ
biomedich-176	102	9	,	,	PUNCT
biomedich-176	102	10	each	each	PRON
biomedich-176	102	11	with	with	ADP
biomedich-176	102	12	several	several	ADJ
biomedich-176	102	13	applications	application	NOUN
biomedich-176	102	14	:	:	PUNCT
biomedich-176	102	15	fullchromosome	fullchromosome	VERB
biomedich-176	102	16	painting	painting	NOUN
biomedich-176	102	17	probes	probe	NOUN
biomedich-176	102	18	,	,	PUNCT
biomedich-176	102	19	repetitive	repetitive	ADJ
biomedich-176	102	20	sequence	sequence	NOUN
biomedich-176	102	21	probes	probe	NOUN
biomedich-176	102	22	,	,	PUNCT
biomedich-176	102	23	and	and	CCONJ
biomedich-176	102	24	locus	locus	NOUN
biomedich-176	102	25	-	-	PUNCT
biomedich-176	102	26	specific	specific	ADJ
biomedich-176	102	27	probes	probe	NOUN
biomedich-176	102	28	(	(	PUNCT
biomedich-176	102	29	bishop	bishop	NOUN
biomedich-176	102	30	,	,	PUNCT
biomedich-176	102	31	2010	2010	NUM
biomedich-176	102	32	)	)	PUNCT
biomedich-176	102	33	.	.	PUNCT
biomedich-176	103	1	wellprepared	wellprepare	VERB
biomedich-176	103	2	chromosome	chromosome	NOUN
biomedich-176	103	3	distribution	distribution	NOUN
biomedich-176	103	4	and	and	CCONJ
biomedich-176	103	5	an	an	DET
biomedich-176	103	6	effectively	effectively	ADV
biomedich-176	103	7	labeled	label	VERB
biomedich-176	103	8	probe	probe	NOUN
biomedich-176	103	9	are	be	AUX
biomedich-176	103	10	prerequisites	prerequisite	NOUN
biomedich-176	103	11	for	for	ADP
biomedich-176	103	12	a	a	DET
biomedich-176	103	13	good	good	ADJ
biomedich-176	103	14	fish	fish	NOUN
biomedich-176	103	15	experiment	experiment	NOUN
biomedich-176	103	16	.	.	PUNCT
biomedich-176	104	1	nick	nick	NOUN
biomedich-176	104	2	-	-	PUNCT
biomedich-176	104	3	translation	translation	NOUN
biomedich-176	104	4	,	,	PUNCT
biomedich-176	104	5	random	random	ADJ
biomedich-176	104	6	priming	priming	NOUN
biomedich-176	104	7	,	,	PUNCT
biomedich-176	104	8	and	and	CCONJ
biomedich-176	104	9	pcr	pcr	NOUN
biomedich-176	104	10	provide	provide	VERB
biomedich-176	104	11	multiple	multiple	ADJ
biomedich-176	104	12	enzymatic	enzymatic	ADJ
biomedich-176	104	13	methods	method	NOUN
biomedich-176	104	14	for	for	ADP
biomedich-176	104	15	labelling	label	VERB
biomedich-176	104	16	probes	probe	NOUN
biomedich-176	104	17	.	.	PUNCT
biomedich-176	105	1	the	the	DET
biomedich-176	105	2	most	most	ADV
biomedich-176	105	3	common	common	ADJ
biomedich-176	105	4	use	use	NOUN
biomedich-176	105	5	of	of	ADP
biomedich-176	105	6	nick	nick	NOUN
biomedich-176	105	7	-	-	PUNCT
biomedich-176	105	8	translation	translation	NOUN
biomedich-176	105	9	is	be	AUX
biomedich-176	105	10	48	48	NUM
biomedich-176	105	11	biology	biology	NOUN
biomedich-176	105	12	,	,	PUNCT
biomedich-176	105	13	medicine	medicine	NOUN
biomedich-176	105	14	,	,	PUNCT
biomedich-176	105	15	&	&	CCONJ
biomedich-176	105	16	natural	natural	ADJ
biomedich-176	105	17	product	product	NOUN
biomedich-176	105	18	chemistry	chemistry	NOUN
biomedich-176	105	19	11	11	NUM
biomedich-176	105	20	(	(	PUNCT
biomedich-176	105	21	1	1	NUM
biomedich-176	105	22	)	)	PUNCT
biomedich-176	105	23	,	,	PUNCT
biomedich-176	105	24	2022	2022	NUM
biomedich-176	105	25	:	:	PUNCT
biomedich-176	105	26	45	45	NUM
biomedich-176	105	27	-	-	SYM
biomedich-176	105	28	54	54	NUM
biomedich-176	105	29	(	(	PUNCT
biomedich-176	105	30	gozzetti	gozzetti	NOUN
biomedich-176	105	31	and	and	CCONJ
biomedich-176	105	32	le	le	X
biomedich-176	105	33	,	,	PUNCT
biomedich-176	105	34	2000	2000	NUM
biomedich-176	105	35	)	)	PUNCT
biomedich-176	105	36	.	.	PUNCT
biomedich-176	106	1	in	in	ADP
biomedich-176	106	2	conducting	conduct	VERB
biomedich-176	106	3	efficient	efficient	ADJ
biomedich-176	106	4	3d	3d	NUM
biomedich-176	106	5	fish	fish	NOUN
biomedich-176	106	6	experiments	experiment	NOUN
biomedich-176	106	7	,	,	PUNCT
biomedich-176	106	8	there	there	PRON
biomedich-176	106	9	are	be	VERB
biomedich-176	106	10	two	two	NUM
biomedich-176	106	11	major	major	ADJ
biomedich-176	106	12	considerations	consideration	NOUN
biomedich-176	106	13	.	.	PUNCT
biomedich-176	107	1	to	to	PART
biomedich-176	107	2	maintain	maintain	VERB
biomedich-176	107	3	nuclear	nuclear	ADJ
biomedich-176	107	4	morphology	morphology	NOUN
biomedich-176	107	5	as	as	ADV
biomedich-176	107	6	much	much	ADV
biomedich-176	107	7	as	as	ADP
biomedich-176	107	8	possible	possible	ADJ
biomedich-176	107	9	while	while	SCONJ
biomedich-176	107	10	keeping	keep	VERB
biomedich-176	107	11	dna	dna	NOUN
biomedich-176	107	12	sufficiently	sufficiently	ADV
biomedich-176	107	13	accessible	accessible	ADJ
biomedich-176	107	14	for	for	ADP
biomedich-176	107	15	probe	probe	NOUN
biomedich-176	107	16	hybridization	hybridization	NOUN
biomedich-176	107	17	,	,	PUNCT
biomedich-176	107	18	the	the	DET
biomedich-176	107	19	option	option	NOUN
biomedich-176	107	20	of	of	ADP
biomedich-176	107	21	cellular	cellular	ADJ
biomedich-176	107	22	treatments	treatment	NOUN
biomedich-176	107	23	,	,	PUNCT
biomedich-176	107	24	including	include	VERB
biomedich-176	107	25	fixation	fixation	NOUN
biomedich-176	107	26	,	,	PUNCT
biomedich-176	107	27	pre	pre	ADJ
biomedich-176	107	28	-	-	ADJ
biomedich-176	107	29	and	and	CCONJ
biomedich-176	107	30	post	post	ADJ
biomedich-176	107	31	-	-	ADJ
biomedich-176	107	32	hybridization	hybridization	ADJ
biomedich-176	107	33	steps	step	NOUN
biomedich-176	107	34	(	(	PUNCT
biomedich-176	107	35	bolland	bolland	PROPN
biomedich-176	107	36	et	et	PROPN
biomedich-176	107	37	al	al	PROPN
biomedich-176	107	38	.	.	PROPN
biomedich-176	107	39	,	,	PUNCT
biomedich-176	107	40	2013	2013	NUM
biomedich-176	107	41	)	)	PUNCT
biomedich-176	107	42	.	.	PUNCT
biomedich-176	108	1	figure	figure	NOUN
biomedich-176	108	2	1	1	NUM
biomedich-176	108	3	.	.	PUNCT
biomedich-176	109	1	the	the	DET
biomedich-176	109	2	fish	fish	NOUN
biomedich-176	109	3	spot	spot	NOUN
biomedich-176	109	4	detection	detection	NOUN
biomedich-176	109	5	algorithm	algorithm	NOUN
biomedich-176	109	6	(	(	PUNCT
biomedich-176	109	7	les	les	X
biomedich-176	109	8	et	et	PROPN
biomedich-176	109	9	al	al	PROPN
biomedich-176	109	10	.	.	PROPN
biomedich-176	109	11	,	,	PUNCT
biomedich-176	109	12	2014	2014	NUM
biomedich-176	109	13	)	)	PUNCT
biomedich-176	109	14	.	.	PUNCT
biomedich-176	110	1	figure	figure	NOUN
biomedich-176	110	2	2	2	NUM
biomedich-176	110	3	.	.	PUNCT
biomedich-176	111	1	fluorescence	fluorescence	NOUN
biomedich-176	111	2	in	in	ADP
biomedich-176	111	3	situ	situ	ADJ
biomedich-176	111	4	hybridization	hybridization	NOUN
biomedich-176	111	5	(	(	PUNCT
biomedich-176	111	6	fish	fish	NOUN
biomedich-176	111	7	)	)	PUNCT
biomedich-176	111	8	applications	application	NOUN
biomedich-176	111	9	in	in	ADP
biomedich-176	111	10	genetic	genetic	ADJ
biomedich-176	111	11	diagnostics	diagnostic	NOUN
biomedich-176	111	12	on	on	ADP
biomedich-176	111	13	ffpe	ffpe	ADJ
biomedich-176	111	14	content	content	NOUN
biomedich-176	111	15	in	in	ADP
biomedich-176	111	16	solid	solid	ADJ
biomedich-176	111	17	tumours	tumour	NOUN
biomedich-176	111	18	:	:	PUNCT
biomedich-176	111	19	a-1p/19q	a-1p/19q	NOUN
biomedich-176	111	20	probe	probe	NOUN
biomedich-176	111	21	:	:	PUNCT
biomedich-176	111	22	a1	a1	NOUN
biomedich-176	111	23	deletion	deletion	NOUN
biomedich-176	111	24	of	of	ADP
biomedich-176	111	25	1p32	1p32	NUM
biomedich-176	111	26	locus	locus	NOUN
biomedich-176	111	27	,	,	PUNCT
biomedich-176	111	28	a-2	a-2	ADJ
biomedich-176	111	29	natural	natural	ADJ
biomedich-176	111	30	signal	signal	NOUN
biomedich-176	111	31	pattern	pattern	NOUN
biomedich-176	111	32	(	(	PUNCT
biomedich-176	111	33	cell	cell	NOUN
biomedich-176	111	34	on	on	ADP
biomedich-176	111	35	the	the	DET
biomedich-176	111	36	left	left	NOUN
biomedich-176	111	37	)	)	PUNCT
biomedich-176	111	38	and	and	CCONJ
biomedich-176	111	39	19q13	19q13	NUM
biomedich-176	111	40	locus	locus	NOUN
biomedich-176	111	41	deletion	deletion	NOUN
biomedich-176	111	42	(	(	PUNCT
biomedich-176	111	43	cell	cell	NOUN
biomedich-176	111	44	on	on	ADP
biomedich-176	111	45	the	the	DET
biomedich-176	111	46	right	right	NOUN
biomedich-176	111	47	)	)	PUNCT
biomedich-176	111	48	,	,	PUNCT
biomedich-176	111	49	a-3	a-3	PROPN
biomedich-176	111	50	normal	normal	ADJ
biomedich-176	111	51	signal	signal	NOUN
biomedich-176	111	52	pattern	pattern	NOUN
biomedich-176	111	53	(	(	PUNCT
biomedich-176	111	54	abbott	abbott	PROPN
biomedich-176	111	55	molecular	molecular	PROPN
biomedich-176	111	56	)	)	PUNCT
biomedich-176	111	57	,	,	PUNCT
biomedich-176	111	58	b	b	X
biomedich-176	111	59	-	-	PUNCT
biomedich-176	111	60	dual	dual	ADJ
biomedich-176	111	61	fusion	fusion	NOUN
biomedich-176	111	62	probe	probe	NOUN
biomedich-176	111	63	:	:	PUNCT
biomedich-176	111	64	col1a1	col1a1	NOUN
biomedich-176	111	65	and	and	CCONJ
biomedich-176	111	66	pdgfb	pdgfb	ADJ
biomedich-176	111	67	loci	loci	NOUN
biomedich-176	111	68	fusion	fusion	NOUN
biomedich-176	111	69	and	and	CCONJ
biomedich-176	111	70	normal	normal	ADJ
biomedich-176	111	71	signal	signal	NOUN
biomedich-176	111	72	pattern	pattern	NOUN
biomedich-176	111	73	(	(	PUNCT
biomedich-176	111	74	zytovision	zytovision	NOUN
biomedich-176	111	75	)	)	PUNCT
biomedich-176	111	76	,	,	PUNCT
biomedich-176	111	77	c	c	X
biomedich-176	111	78	-	-	PUNCT
biomedich-176	111	79	break	break	VERB
biomedich-176	111	80	apart	apart	ADJ
biomedich-176	111	81	probe	probe	NOUN
biomedich-176	111	82	:	:	PUNCT
biomedich-176	111	83	c-1	c-1	NOUN
biomedich-176	111	84	alk	alk	PROPN
biomedich-176	111	85	gene	gene	NOUN
biomedich-176	111	86	rearrangement	rearrangement	NOUN
biomedich-176	111	87	,	,	PUNCT
biomedich-176	111	88	c-2	c-2	NOUN
biomedich-176	111	89	normal	normal	ADJ
biomedich-176	111	90	signal	signal	NOUN
biomedich-176	111	91	pattern	pattern	NOUN
biomedich-176	111	92	(	(	PUNCT
biomedich-176	111	93	abbott	abbott	PROPN
biomedich-176	111	94	molecular	molecular	PROPN
biomedich-176	111	95	)	)	PUNCT
biomedich-176	111	96	,	,	PUNCT
biomedich-176	111	97	d	d	X
biomedich-176	111	98	-	-	PUNCT
biomedich-176	111	99	break	break	ADJ
biomedich-176	111	100	apart	apart	ADJ
biomedich-176	111	101	probe	probe	NOUN
biomedich-176	111	102	:	:	PUNCT
biomedich-176	111	103	ewsr1	ewsr1	X
biomedich-176	112	1	locus	locus	ADJ
biomedich-176	112	2	rearrangement	rearrangement	NOUN
biomedich-176	112	3	(	(	PUNCT
biomedich-176	112	4	abbott	abbott	PROPN
biomedich-176	112	5	molecular	molecular	PROPN
biomedich-176	112	6	)	)	PUNCT
biomedich-176	112	7	,	,	PUNCT
biomedich-176	112	8	f	f	X
biomedich-176	112	9	-	-	PUNCT
biomedich-176	112	10	break	break	VERB
biomedich-176	112	11	apart	apart	ADJ
biomedich-176	112	12	probe	probe	NOUN
biomedich-176	112	13	:	:	PUNCT
biomedich-176	112	14	f-1	f-1	NOUN
biomedich-176	112	15	rearrangement	rearrangement	NOUN
biomedich-176	112	16	(	(	PUNCT
biomedich-176	112	17	empire	empire	NOUN
biomedich-176	112	18	genomics	genomic	NOUN
biomedich-176	112	19	)	)	PUNCT
biomedich-176	112	20	,	,	PUNCT
biomedich-176	112	21	g	g	NOUN
biomedich-176	112	22	-	-	PUNCT
biomedich-176	112	23	locus	locus	ADJ
biomedich-176	112	24	specific	specific	ADJ
biomedich-176	112	25	probe	probe	NOUN
biomedich-176	112	26	:	:	PUNCT
biomedich-176	112	27	g-1	g-1	PROPN
biomedich-176	112	28	her2	her2	VERB
biomedich-176	112	29	locus	locus	ADJ
biomedich-176	112	30	amplification	amplification	NOUN
biomedich-176	112	31	,	,	PUNCT
biomedich-176	112	32	g-2	g-2	ADJ
biomedich-176	112	33	normal	normal	ADJ
biomedich-176	112	34	signal	signal	NOUN
biomedich-176	112	35	pattern	pattern	NOUN
biomedich-176	112	36	(	(	PUNCT
biomedich-176	112	37	abbott	abbott	PROPN
biomedich-176	112	38	molecular	molecular	PROPN
biomedich-176	112	39	)	)	PUNCT
biomedich-176	112	40	,	,	PUNCT
biomedich-176	112	41	e	e	X
biomedich-176	112	42	-	-	NOUN
biomedich-176	112	43	break	break	ADJ
biomedich-176	112	44	apart	apart	ADJ
biomedich-176	112	45	probe	probe	NOUN
biomedich-176	112	46	:	:	PUNCT
biomedich-176	112	47	normal	normal	ADJ
biomedich-176	112	48	ss18	ss18	PROPN
biomedich-176	112	49	locus	locus	NOUN
biomedich-176	112	50	signal	signal	NOUN
biomedich-176	112	51	pattern	pattern	NOUN
biomedich-176	112	52	,	,	PUNCT
biomedich-176	112	53	green	green	ADJ
biomedich-176	112	54	colour	colour	NOUN
biomedich-176	112	55	—	—	PUNCT
biomedich-176	112	56	pdgfb	pdgfb	ADJ
biomedich-176	112	57	gene	gene	NOUN
biomedich-176	112	58	locus	locus	NOUN
biomedich-176	112	59	,	,	PUNCT
biomedich-176	112	60	yellow	yellow	ADJ
biomedich-176	112	61	colour	colour	NOUN
biomedich-176	112	62	—	—	PUNCT
biomedich-176	112	63	the	the	DET
biomedich-176	112	64	fusion	fusion	NOUN
biomedich-176	112	65	of	of	ADP
biomedich-176	112	66	col1a1pdgfb	col1a1pdgfb	PROPN
biomedich-176	112	67	and	and	CCONJ
biomedich-176	112	68	pdgfb	pdgfb	ADJ
biomedich-176	112	69	-	-	PUNCT
biomedich-176	112	70	col1a1	col1a1	NOUN
biomedich-176	112	71	(	(	PUNCT
biomedich-176	112	72	chrzanowska	chrzanowska	VERB
biomedich-176	112	73	et	et	PROPN
biomedich-176	112	74	al	al	PROPN
biomedich-176	112	75	.	.	PROPN
biomedich-176	112	76	,2020	,2020	PROPN
biomedich-176	112	77	)	)	PUNCT
biomedich-176	112	78	.	.	PUNCT
biomedich-176	113	1	figure	figure	VERB
biomedich-176	113	2	3	3	NUM
biomedich-176	113	3	.	.	PUNCT
biomedich-176	113	4	detection	detection	NOUN
biomedich-176	113	5	of	of	ADP
biomedich-176	113	6	di	di	NOUN
biomedich-176	113	7	-	-	ADJ
biomedich-176	113	8	centric	centric	ADJ
biomedich-176	113	9	,	,	PUNCT
biomedich-176	113	10	tri	tri	ADJ
biomedich-176	113	11	-	-	ADJ
biomedich-176	113	12	centric	centric	ADJ
biomedich-176	113	13	,	,	PUNCT
biomedich-176	113	14	and	and	CCONJ
biomedich-176	113	15	tetra	tetra	NOUN
biomedich-176	113	16	-	-	PUNCT
biomedich-176	113	17	centric	centric	ADJ
biomedich-176	113	18	ring	ring	NOUN
biomedich-176	113	19	chromosome	chromosome	NOUN
biomedich-176	113	20	18	18	NUM
biomedich-176	113	21	using	use	VERB
biomedich-176	113	22	a	a	DET
biomedich-176	113	23	centromeric	centromeric	ADJ
biomedich-176	113	24	probe	probe	NOUN
biomedich-176	113	25	d18z2	d18z2	PROPN
biomedich-176	113	26	for	for	ADP
biomedich-176	113	27	chromosome	chromosome	NOUN
biomedich-176	113	28	18	18	NUM
biomedich-176	113	29	.	.	PUNCT
biomedich-176	114	1	the	the	DET
biomedich-176	114	2	left	left	ADJ
biomedich-176	114	3	panel	panel	NOUN
biomedich-176	114	4	shows	show	VERB
biomedich-176	114	5	regular	regular	ADJ
biomedich-176	114	6	chromosome	chromosome	NOUN
biomedich-176	114	7	18	18	NUM
biomedich-176	114	8	,	,	PUNCT
biomedich-176	114	9	the	the	DET
biomedich-176	114	10	top	top	ADJ
biomedich-176	114	11	dicentric	dicentric	ADJ
biomedich-176	114	12	ring	ring	NOUN
biomedich-176	114	13	18	18	NUM
biomedich-176	114	14	and	and	CCONJ
biomedich-176	114	15	the	the	DET
biomedich-176	114	16	bottom	bottom	ADJ
biomedich-176	114	17	tetracentric	tetracentric	NOUN
biomedich-176	114	18	ring	ring	NOUN
biomedich-176	114	19	18	18	NUM
biomedich-176	114	20	.	.	PUNCT
biomedich-176	115	1	the	the	DET
biomedich-176	115	2	right	right	ADJ
biomedich-176	115	3	panel	panel	NOUN
biomedich-176	115	4	shows	show	VERB
biomedich-176	115	5	dicentric	dicentric	ADJ
biomedich-176	115	6	ring	ring	NOUN
biomedich-176	115	7	18	18	NUM
biomedich-176	115	8	and	and	CCONJ
biomedich-176	115	9	fish	fish	NOUN
biomedich-176	115	10	insets	inset	NOUN
biomedich-176	115	11	pericentric	pericentric	ADJ
biomedich-176	115	12	/	/	SYM
biomedich-176	115	13	tetracentric	tetracentric	NOUN
biomedich-176	115	14	ring	ring	NOUN
biomedich-176	115	15	18	18	NUM
biomedich-176	115	16	.	.	PUNCT
biomedich-176	116	1	(	(	PUNCT
biomedich-176	116	2	b	b	X
biomedich-176	116	3	)	)	PUNCT
biomedich-176	116	4	identification	identification	NOUN
biomedich-176	116	5	of	of	ADP
biomedich-176	116	6	a	a	DET
biomedich-176	116	7	2q32/16p13.3	2q32/16p13.3	NUM
biomedich-176	116	8	translocation	translocation	NOUN
biomedich-176	116	9	derivative	derivative	NOUN
biomedich-176	116	10	of	of	ADP
biomedich-176	116	11	chromosome	chromosome	NOUN
biomedich-176	116	12	16	16	NUM
biomedich-176	116	13	by	by	ADP
biomedich-176	116	14	complete	complete	ADJ
biomedich-176	116	15	chromosome	chromosome	NOUN
biomedich-176	116	16	painting	painting	NOUN
biomedich-176	116	17	probes	probe	NOUN
biomedich-176	116	18	for	for	ADP
biomedich-176	116	19	chromosome	chromosome	NOUN
biomedich-176	116	20	2	2	NUM
biomedich-176	116	21	(	(	PUNCT
biomedich-176	116	22	wcp2	wcp2	PROPN
biomedich-176	116	23	)	)	PUNCT
biomedich-176	116	24	and	and	CCONJ
biomedich-176	116	25	16	16	NUM
biomedich-176	116	26	(	(	PUNCT
biomedich-176	116	27	wcp2	wcp2	PROPN
biomedich-176	116	28	)	)	PUNCT
biomedich-176	116	29	(	(	PUNCT
biomedich-176	116	30	wcp16	wcp16	NOUN
biomedich-176	116	31	)	)	PUNCT
biomedich-176	116	32	.	.	PUNCT
biomedich-176	117	1	(	(	PUNCT
biomedich-176	117	2	c	c	X
biomedich-176	117	3	)	)	PUNCT
biomedich-176	117	4	identification	identification	NOUN
biomedich-176	117	5	by	by	ADP
biomedich-176	117	6	dual	dual	ADJ
biomedich-176	117	7	-	-	PUNCT
biomedich-176	117	8	colour	colour	NOUN
biomedich-176	117	9	double	double	ADJ
biomedich-176	117	10	fusion	fusion	NOUN
biomedich-176	117	11	probes	probe	NOUN
biomedich-176	117	12	of	of	ADP
biomedich-176	117	13	abl1	abl1	PROPN
biomedich-176	117	14	/	/	SYM
biomedich-176	117	15	bcr	bcr	PROPN
biomedich-176	117	16	gene	gene	NOUN
biomedich-176	117	17	fusions	fusion	NOUN
biomedich-176	117	18	in	in	ADP
biomedich-176	117	19	interphase	interphase	ADJ
biomedich-176	117	20	and	and	CCONJ
biomedich-176	117	21	metaphase	metaphase	NOUN
biomedich-176	117	22	cells	cell	NOUN
biomedich-176	117	23	(	(	PUNCT
biomedich-176	117	24	thin	thin	ADJ
biomedich-176	117	25	arrows	arrow	NOUN
biomedich-176	117	26	point	point	VERB
biomedich-176	117	27	to	to	ADP
biomedich-176	117	28	the	the	DET
biomedich-176	117	29	normal	normal	ADJ
biomedich-176	117	30	signal	signal	NOUN
biomedich-176	117	31	and	and	CCONJ
biomedich-176	118	1	thick	thick	ADJ
biomedich-176	118	2	arrows	arrow	NOUN
biomedich-176	118	3	point	point	VERB
biomedich-176	118	4	to	to	ADP
biomedich-176	118	5	the	the	DET
biomedich-176	118	6	abnormal	abnormal	ADJ
biomedich-176	118	7	fusion	fusion	NOUN
biomedich-176	118	8	signals	signal	NOUN
biomedich-176	118	9	)	)	PUNCT
biomedich-176	118	10	.	.	PUNCT
biomedich-176	119	1	(	(	PUNCT
biomedich-176	119	2	d	d	X
biomedich-176	119	3	)	)	PUNCT
biomedich-176	119	4	diagnostic	diagnostic	ADJ
biomedich-176	119	5	use	use	NOUN
biomedich-176	119	6	of	of	ADP
biomedich-176	119	7	the	the	DET
biomedich-176	119	8	etv6	etv6	NOUN
biomedich-176	119	9	and	and	CCONJ
biomedich-176	119	10	runx1	runx1	NOUN
biomedich-176	119	11	probes	probe	NOUN
biomedich-176	119	12	for	for	ADP
biomedich-176	119	13	the	the	DET
biomedich-176	119	14	identification	identification	NOUN
biomedich-176	119	15	of	of	ADP
biomedich-176	119	16	two	two	NUM
biomedich-176	119	17	cryptic	cryptic	ADJ
biomedich-176	119	18	t(12;21	t(12;21	NOUN
biomedich-176	119	19	)	)	PUNCT
biomedich-176	119	20	(	(	PUNCT
biomedich-176	119	21	p13;q22	p13;q22	ADJ
biomedich-176	119	22	)	)	PUNCT
biomedich-176	119	23	fusion	fusion	NOUN
biomedich-176	119	24	signals	signal	NOUN
biomedich-176	119	25	,	,	PUNCT
biomedich-176	119	26	loss	loss	NOUN
biomedich-176	119	27	of	of	ADP
biomedich-176	119	28	etv6	etv6	PROPN
biomedich-176	119	29	signal	signal	NOUN
biomedich-176	119	30	and	and	CCONJ
biomedich-176	119	31	gain	gain	NOUN
biomedich-176	119	32	of	of	ADP
biomedich-176	119	33	three	three	NUM
biomedich-176	119	34	additional	additional	ADJ
biomedich-176	119	35	runx1	runx1	NOUN
biomedich-176	119	36	signals	signal	NOUN
biomedich-176	119	37	(	(	PUNCT
biomedich-176	119	38	thin	thin	ADJ
biomedich-176	119	39	arrows	arrow	NOUN
biomedich-176	119	40	point	point	VERB
biomedich-176	119	41	to	to	ADP
biomedich-176	119	42	the	the	DET
biomedich-176	119	43	fusion	fusion	NOUN
biomedich-176	119	44	signals	signal	NOUN
biomedich-176	119	45	and	and	CCONJ
biomedich-176	119	46	thick	thick	ADJ
biomedich-176	119	47	arrows	arrow	NOUN
biomedich-176	119	48	to	to	ADP
biomedich-176	119	49	extra	extra	ADJ
biomedich-176	119	50	runx1	runx1	NOUN
biomedich-176	119	51	signals	signal	NOUN
biomedich-176	119	52	)	)	PUNCT
biomedich-176	119	53	.	.	PUNCT
biomedich-176	120	1	all	all	DET
biomedich-176	120	2	images	image	NOUN
biomedich-176	120	3	are	be	AUX
biomedich-176	120	4	from	from	ADP
biomedich-176	120	5	yale	yale	PROPN
biomedich-176	120	6	clinical	clinical	PROPN
biomedich-176	120	7	cytogenetics	cytogenetic	NOUN
biomedich-176	120	8	laboratory	laboratory	NOUN
biomedich-176	120	9	(	(	PUNCT
biomedich-176	120	10	cui	cui	VERB
biomedich-176	120	11	et	et	PROPN
biomedich-176	120	12	al	al	PROPN
biomedich-176	120	13	.	.	PROPN
biomedich-176	120	14	,2016	,2016	PUNCT
biomedich-176	120	15	)	)	PUNCT
biomedich-176	120	16	.	.	PUNCT
biomedich-176	121	1	smail	smail	NOUN
biomedich-176	121	2	–	–	PUNCT
biomedich-176	121	3	the	the	DET
biomedich-176	121	4	roles	role	NOUN
biomedich-176	121	5	of	of	ADP
biomedich-176	121	6	the	the	DET
biomedich-176	121	7	fluorescent	fluorescent	NOUN
biomedich-176	121	8	in	in	ADP
biomedich-176	121	9	situ	situ	ADJ
biomedich-176	121	10	hybridization	hybridization	NOUN
biomedich-176	121	11	(	(	PUNCT
biomedich-176	121	12	fish	fish	NOUN
biomedich-176	121	13	)	)	PUNCT
biomedich-176	121	14	and	and	CCONJ
biomedich-176	121	15	…	…	PUNCT
biomedich-176	121	16	49	49	NUM
biomedich-176	121	17	figure	figure	NOUN
biomedich-176	121	18	4	4	NUM
biomedich-176	121	19	.	.	PUNCT
biomedich-176	122	1	using	use	VERB
biomedich-176	122	2	whole	whole	ADJ
biomedich-176	122	3	-	-	PUNCT
biomedich-176	122	4	chromosome	chromosome	NOUN
biomedich-176	122	5	-	-	PUNCT
biomedich-176	122	6	painting	paint	VERB
biomedich-176	122	7	probes	probe	NOUN
biomedich-176	122	8	,	,	PUNCT
biomedich-176	122	9	fluorescence	fluorescence	NOUN
biomedich-176	122	10	in	in	ADP
biomedich-176	122	11	situ	situ	ADJ
biomedich-176	122	12	hybridization	hybridization	NOUN
biomedich-176	122	13	(	(	PUNCT
biomedich-176	122	14	fish	fish	NOUN
biomedich-176	122	15	)	)	PUNCT
biomedich-176	122	16	.	.	PUNCT
biomedich-176	123	1	to	to	PART
biomedich-176	123	2	rule	rule	VERB
biomedich-176	123	3	out	out	ADP
biomedich-176	123	4	the	the	DET
biomedich-176	123	5	presence	presence	NOUN
biomedich-176	123	6	of	of	ADP
biomedich-176	123	7	an	an	DET
biomedich-176	123	8	additional	additional	ADJ
biomedich-176	123	9	copy	copy	NOUN
biomedich-176	123	10	of	of	ADP
biomedich-176	123	11	chromosome	chromosome	NOUN
biomedich-176	123	12	19	19	NUM
biomedich-176	123	13	(	(	PUNCT
biomedich-176	123	14	i.e.	i.e.	X
biomedich-176	123	15	trisomy	trisomy	NOUN
biomedich-176	123	16	19	19	NUM
biomedich-176	123	17	)	)	PUNCT
biomedich-176	123	18	in	in	ADP
biomedich-176	123	19	this	this	DET
biomedich-176	123	20	metaphase	metaphase	NOUN
biomedich-176	123	21	distribution	distribution	NOUN
biomedich-176	123	22	,	,	PUNCT
biomedich-176	123	23	derived	derive	VERB
biomedich-176	123	24	from	from	ADP
biomedich-176	123	25	a	a	DET
biomedich-176	123	26	glial	glial	ADJ
biomedich-176	123	27	cell	cell	NOUN
biomedich-176	123	28	taken	take	VERB
biomedich-176	123	29	from	from	ADP
biomedich-176	123	30	a	a	DET
biomedich-176	123	31	mouse	mouse	NOUN
biomedich-176	123	32	's	's	PART
biomedich-176	123	33	brain	brain	NOUN
biomedich-176	123	34	,	,	PUNCT
biomedich-176	123	35	chromosome	chromosome	NOUN
biomedich-176	123	36	painting	painting	NOUN
biomedich-176	123	37	probes	probe	NOUN
biomedich-176	123	38	were	be	AUX
biomedich-176	123	39	used	use	VERB
biomedich-176	123	40	.	.	PUNCT
biomedich-176	124	1	chromosome	chromosome	NOUN
biomedich-176	124	2	19	19	NUM
biomedich-176	124	3	is	be	AUX
biomedich-176	124	4	green	green	ADJ
biomedich-176	124	5	in	in	ADP
biomedich-176	124	6	colour	colour	NOUN
biomedich-176	124	7	(	(	PUNCT
biomedich-176	124	8	mcneil	mcneil	PROPN
biomedich-176	124	9	and	and	CCONJ
biomedich-176	124	10	ried	rie	VERB
biomedich-176	124	11	2000	2000	NUM
biomedich-176	124	12	)	)	PUNCT
biomedich-176	124	13	.	.	PUNCT
biomedich-176	125	1	important	important	ADJ
biomedich-176	125	2	comparative	comparative	ADJ
biomedich-176	125	3	genomic	genomic	NOUN
biomedich-176	125	4	hybridization	hybridization	NOUN
biomedich-176	125	5	in	in	ADP
biomedich-176	125	6	early	early	ADJ
biomedich-176	125	7	detection	detection	NOUN
biomedich-176	125	8	of	of	ADP
biomedich-176	125	9	breast	breast	NOUN
biomedich-176	125	10	cancer	cancer	NOUN
biomedich-176	125	11	comparative	comparative	ADJ
biomedich-176	125	12	genomic	genomic	NOUN
biomedich-176	125	13	hybridization	hybridization	NOUN
biomedich-176	125	14	(	(	PUNCT
biomedich-176	125	15	cgh	cgh	PROPN
biomedich-176	125	16	)	)	PUNCT
biomedich-176	125	17	has	have	AUX
biomedich-176	125	18	emerged	emerge	VERB
biomedich-176	125	19	to	to	PART
biomedich-176	125	20	promote	promote	VERB
biomedich-176	125	21	the	the	DET
biomedich-176	125	22	aggregation	aggregation	NOUN
biomedich-176	125	23	of	of	ADP
biomedich-176	125	24	high	high	ADJ
biomedich-176	125	25	-	-	PUNCT
biomedich-176	125	26	resolution	resolution	NOUN
biomedich-176	125	27	data	datum	NOUN
biomedich-176	125	28	of	of	ADP
biomedich-176	125	29	cancer	cancer	NOUN
biomedich-176	125	30	-	-	PUNCT
biomedich-176	125	31	associated	associate	VERB
biomedich-176	125	32	genomic	genomic	NOUN
biomedich-176	125	33	imbalances	imbalance	NOUN
biomedich-176	125	34	as	as	ADP
biomedich-176	125	35	a	a	DET
biomedich-176	125	36	highthroughput	highthroughput	ADJ
biomedich-176	125	37	genomic	genomic	ADJ
biomedich-176	125	38	technology	technology	NOUN
biomedich-176	125	39	.	.	PUNCT
biomedich-176	126	1	high	high	ADJ
biomedich-176	126	2	-	-	PUNCT
biomedich-176	126	3	resolution	resolution	NOUN
biomedich-176	126	4	genomic	genomic	ADJ
biomedich-176	126	5	microarray	microarray	NOUN
biomedich-176	126	6	cgh	cgh	PROPN
biomedich-176	126	7	(	(	PUNCT
biomedich-176	126	8	li	li	PROPN
biomedich-176	126	9	et	et	PROPN
biomedich-176	126	10	al	al	PROPN
biomedich-176	126	11	.	.	PROPN
biomedich-176	126	12	,	,	PUNCT
biomedich-176	126	13	2020	2020	NUM
biomedich-176	126	14	)	)	PUNCT
biomedich-176	126	15	.	.	PUNCT
biomedich-176	127	1	the	the	DET
biomedich-176	127	2	rapidly	rapidly	ADV
biomedich-176	127	3	growing	grow	VERB
biomedich-176	127	4	cgh	cgh	PROPN
biomedich-176	127	5	publication	publication	NOUN
biomedich-176	127	6	database	database	NOUN
biomedich-176	127	7	already	already	ADV
biomedich-176	127	8	contains	contain	VERB
biomedich-176	127	9	around	around	ADP
biomedich-176	127	10	1500	1500	NUM
biomedich-176	127	11	tumours	tumour	NOUN
biomedich-176	127	12	and	and	CCONJ
biomedich-176	127	13	is	be	AUX
biomedich-176	127	14	beginning	begin	VERB
biomedich-176	127	15	to	to	PART
biomedich-176	127	16	reveal	reveal	VERB
biomedich-176	127	17	genetic	genetic	ADJ
biomedich-176	127	18	anomalies	anomaly	NOUN
biomedich-176	127	19	characteristic	characteristic	ADJ
biomedich-176	127	20	of	of	ADP
biomedich-176	127	21	certain	certain	ADJ
biomedich-176	127	22	forms	form	NOUN
biomedich-176	127	23	of	of	ADP
biomedich-176	127	24	tumour	tumour	NOUN
biomedich-176	127	25	or	or	CCONJ
biomedich-176	127	26	stages	stage	NOUN
biomedich-176	127	27	of	of	ADP
biomedich-176	127	28	tumour	tumour	NOUN
biomedich-176	127	29	progression	progression	NOUN
biomedich-176	127	30	(	(	PUNCT
biomedich-176	127	31	forozan	forozan	PROPN
biomedich-176	127	32	et	et	PROPN
biomedich-176	127	33	al	al	PROPN
biomedich-176	127	34	.	.	PROPN
biomedich-176	127	35	,1997	,1997	PUNCT
biomedich-176	127	36	)	)	PUNCT
biomedich-176	127	37	.	.	PUNCT
biomedich-176	128	1	comparative	comparative	ADJ
biomedich-176	128	2	genomic	genomic	NOUN
biomedich-176	128	3	hybridization	hybridization	NOUN
biomedich-176	128	4	has	have	AUX
biomedich-176	128	5	created	create	VERB
biomedich-176	128	6	dna	dna	PROPN
biomedich-176	128	7	copy	copy	VERB
biomedich-176	128	8	number	number	NOUN
biomedich-176	128	9	profiles	profile	NOUN
biomedich-176	128	10	for	for	ADP
biomedich-176	128	11	most	most	ADJ
biomedich-176	128	12	of	of	ADP
biomedich-176	128	13	the	the	DET
biomedich-176	128	14	publicly	publicly	ADV
biomedich-176	128	15	available	available	ADJ
biomedich-176	128	16	breast	breast	NOUN
biomedich-176	128	17	cancer	cancer	NOUN
biomedich-176	128	18	cell	cell	NOUN
biomedich-176	128	19	lines	line	NOUN
biomedich-176	128	20	(	(	PUNCT
biomedich-176	128	21	forozan	forozan	PROPN
biomedich-176	128	22	et	et	PROPN
biomedich-176	128	23	al	al	PROPN
biomedich-176	128	24	.	.	PROPN
biomedich-176	128	25	,	,	PUNCT
biomedich-176	128	26	2000	2000	NUM
biomedich-176	128	27	)	)	PUNCT
biomedich-176	128	28	.	.	PUNCT
biomedich-176	129	1	highresolution	highresolution	NOUN
biomedich-176	129	2	cgh	cgh	PROPN
biomedich-176	129	3	analysis	analysis	NOUN
biomedich-176	129	4	of	of	ADP
biomedich-176	129	5	breast	breast	NOUN
biomedich-176	129	6	cancer	cancer	NOUN
biomedich-176	129	7	shows	show	VERB
biomedich-176	129	8	nonrandom	nonrandom	NOUN
biomedich-176	129	9	associations	association	NOUN
biomedich-176	129	10	between	between	ADP
biomedich-176	129	11	particular	particular	ADJ
biomedich-176	129	12	amplicons	amplicon	NOUN
biomedich-176	129	13	in	in	ADP
biomedich-176	129	14	many	many	ADJ
biomedich-176	129	15	regions	region	NOUN
biomedich-176	129	16	where	where	SCONJ
biomedich-176	129	17	dna	dna	PROPN
biomedich-176	129	18	copy	copy	VERB
biomedich-176	129	19	number	number	NOUN
biomedich-176	129	20	is	be	AUX
biomedich-176	129	21	frequently	frequently	ADV
biomedich-176	129	22	obtained	obtain	VERB
biomedich-176	129	23	or	or	CCONJ
biomedich-176	129	24	lost	lose	VERB
biomedich-176	129	25	.	.	PUNCT
biomedich-176	130	1	that	that	DET
biomedich-176	130	2	specific	specific	ADJ
biomedich-176	130	3	genetic	genetic	ADJ
biomedich-176	130	4	modification	modification	NOUN
biomedich-176	130	5	is	be	AUX
biomedich-176	130	6	preserved	preserve	VERB
biomedich-176	130	7	in	in	ADP
biomedich-176	130	8	breast	breast	NOUN
biomedich-176	130	9	cancer	cancer	NOUN
biomedich-176	130	10	cell	cell	NOUN
biomedich-176	130	11	lines	line	NOUN
biomedich-176	130	12	despite	despite	SCONJ
biomedich-176	130	13	repeated	repeat	VERB
biomedich-176	130	14	passage	passage	NOUN
biomedich-176	130	15	through	through	ADP
biomedich-176	130	16	tissue	tissue	NOUN
biomedich-176	130	17	culture	culture	NOUN
biomedich-176	130	18	(	(	PUNCT
biomedich-176	130	19	climent	climent	PROPN
biomedich-176	130	20	et	et	PROPN
biomedich-176	130	21	al	al	PROPN
biomedich-176	130	22	.	.	PROPN
biomedich-176	130	23	,	,	PUNCT
biomedich-176	130	24	2007	2007	NUM
biomedich-176	130	25	)	)	PUNCT
biomedich-176	130	26	.	.	PUNCT
biomedich-176	131	1	recent	recent	ADJ
biomedich-176	131	2	results	result	NOUN
biomedich-176	131	3	released	release	VERB
biomedich-176	131	4	and	and	CCONJ
biomedich-176	131	5	discussed	discuss	VERB
biomedich-176	131	6	at	at	ADP
biomedich-176	131	7	scientific	scientific	ADJ
biomedich-176	131	8	meetings	meeting	NOUN
biomedich-176	131	9	have	have	AUX
biomedich-176	131	10	suggested	suggest	VERB
biomedich-176	131	11	higher	high	ADJ
biomedich-176	131	12	rates	rate	NOUN
biomedich-176	131	13	of	of	ADP
biomedich-176	131	14	implantation	implantation	NOUN
biomedich-176	131	15	and	and	CCONJ
biomedich-176	131	16	pregnancy	pregnancy	NOUN
biomedich-176	131	17	after	after	ADP
biomedich-176	131	18	microarray	microarray	NOUN
biomedich-176	131	19	testing	testing	NOUN
biomedich-176	131	20	,	,	PUNCT
biomedich-176	131	21	resulting	result	VERB
biomedich-176	131	22	in	in	ADP
biomedich-176	131	23	changes	change	NOUN
biomedich-176	131	24	expected	expect	VERB
biomedich-176	131	25	for	for	ADP
biomedich-176	131	26	quite	quite	DET
biomedich-176	131	27	some	some	DET
biomedich-176	131	28	time	time	NOUN
biomedich-176	131	29	.	.	PUNCT
biomedich-176	132	1	by	by	ADP
biomedich-176	132	2	using	use	VERB
biomedich-176	132	3	markers	marker	NOUN
biomedich-176	132	4	spanning	span	VERB
biomedich-176	132	5	much	much	ADJ
biomedich-176	132	6	of	of	ADP
biomedich-176	132	7	the	the	DET
biomedich-176	132	8	genome	genome	NOUN
biomedich-176	132	9	,	,	PUNCT
biomedich-176	132	10	it	it	PRON
biomedich-176	132	11	is	be	AUX
biomedich-176	132	12	not	not	PART
biomedich-176	132	13	only	only	ADV
biomedich-176	132	14	possible	possible	ADJ
biomedich-176	132	15	to	to	PART
biomedich-176	132	16	detect	detect	VERB
biomedich-176	132	17	aneuploidy	aneuploidy	NOUN
biomedich-176	132	18	in	in	ADP
biomedich-176	132	19	single	single	ADJ
biomedich-176	132	20	cells	cell	NOUN
biomedich-176	132	21	but	but	CCONJ
biomedich-176	132	22	also	also	ADV
biomedich-176	132	23	translocations	translocation	NOUN
biomedich-176	132	24	.	.	PUNCT
biomedich-176	133	1	the	the	DET
biomedich-176	133	2	validation	validation	NOUN
biomedich-176	133	3	results	result	NOUN
biomedich-176	133	4	indicate	indicate	VERB
biomedich-176	133	5	that	that	SCONJ
biomedich-176	133	6	the	the	DET
biomedich-176	133	7	cgh	cgh	PROPN
biomedich-176	133	8	array	array	NOUN
biomedich-176	133	9	in	in	ADP
biomedich-176	133	10	single	single	ADJ
biomedich-176	133	11	cells	cell	NOUN
biomedich-176	133	12	has	have	VERB
biomedich-176	133	13	a	a	DET
biomedich-176	133	14	resolution	resolution	NOUN
biomedich-176	133	15	of	of	ADP
biomedich-176	133	16	6	6	NUM
biomedich-176	133	17	mb	mb	NOUN
biomedich-176	133	18	.	.	PUNCT
biomedich-176	134	1	therefore	therefore	ADV
biomedich-176	134	2	,	,	PUNCT
biomedich-176	134	3	most	most	ADJ
biomedich-176	134	4	translocations	translocation	NOUN
biomedich-176	134	5	can	can	AUX
biomedich-176	134	6	be	be	AUX
biomedich-176	134	7	tested	test	VERB
biomedich-176	134	8	as	as	SCONJ
biomedich-176	134	9	this	this	PRON
biomedich-176	134	10	is	be	AUX
biomedich-176	134	11	also	also	ADV
biomedich-176	134	12	the	the	DET
biomedich-176	134	13	limit	limit	NOUN
biomedich-176	134	14	of	of	ADP
biomedich-176	134	15	karyotyping	karyotyping	NOUN
biomedich-176	134	16	.	.	PUNCT
biomedich-176	135	1	translocations	translocation	NOUN
biomedich-176	135	2	of	of	ADP
biomedich-176	135	3	smaller	small	ADJ
biomedich-176	135	4	exchanged	exchange	VERB
biomedich-176	135	5	fragments	fragment	NOUN
biomedich-176	135	6	may	may	AUX
biomedich-176	135	7	also	also	ADV
biomedich-176	135	8	classify	classify	VERB
biomedich-176	135	9	the	the	DET
biomedich-176	135	10	translocation	translocation	NOUN
biomedich-176	135	11	,	,	PUNCT
biomedich-176	135	12	as	as	SCONJ
biomedich-176	135	13	three	three	NUM
biomedich-176	135	14	out	out	ADP
biomedich-176	135	15	of	of	ADP
biomedich-176	135	16	the	the	DET
biomedich-176	135	17	four	four	NUM
biomedich-176	135	18	fragments	fragment	NOUN
biomedich-176	135	19	are	be	AUX
biomedich-176	135	20	above	above	ADP
biomedich-176	135	21	6	6	NUM
biomedich-176	135	22	mbb	mbb	PROPN
biomedich-176	135	23	fragment	fragment	NOUN
biomedich-176	135	24	(	(	PUNCT
biomedich-176	135	25	(	(	PUNCT
biomedich-176	135	26	munné	munné	NOUN
biomedich-176	135	27	,	,	PUNCT
biomedich-176	135	28	2012	2012	NUM
biomedich-176	135	29	)	)	PUNCT
biomedich-176	135	30	.	.	PUNCT
biomedich-176	136	1	over	over	ADP
biomedich-176	136	2	the	the	DET
biomedich-176	136	3	past	past	ADJ
biomedich-176	136	4	decade	decade	NOUN
biomedich-176	136	5	,	,	PUNCT
biomedich-176	136	6	genomic	genomic	ADJ
biomedich-176	136	7	microarray	microarray	NOUN
biomedich-176	136	8	technology	technology	NOUN
biomedich-176	136	9	has	have	AUX
biomedich-176	136	10	greatly	greatly	ADV
biomedich-176	136	11	matured	mature	VERB
biomedich-176	136	12	.	.	PUNCT
biomedich-176	137	1	the	the	DET
biomedich-176	137	2	technique	technique	NOUN
biomedich-176	137	3	offers	offer	VERB
biomedich-176	137	4	a	a	DET
biomedich-176	137	5	locus	locus	NOUN
biomedich-176	137	6	-	-	PUNCT
biomedich-176	137	7	by	by	ADP
biomedich-176	137	8	-	-	PUNCT
biomedich-176	137	9	locus	locus	ADJ
biomedich-176	137	10	measure	measure	NOUN
biomedich-176	137	11	of	of	ADP
biomedich-176	137	12	the	the	DET
biomedich-176	137	13	variance	variance	NOUN
biomedich-176	137	14	of	of	ADP
biomedich-176	137	15	dna	dna	PROPN
biomedich-176	137	16	copy	copy	NOUN
biomedich-176	137	17	-	-	PUNCT
biomedich-176	137	18	number	number	NOUN
biomedich-176	137	19	(	(	PUNCT
biomedich-176	137	20	cnv	cnv	NOUN
biomedich-176	137	21	)	)	PUNCT
biomedich-176	137	22	and	and	CCONJ
biomedich-176	137	23	represents	represent	VERB
biomedich-176	137	24	another	another	DET
biomedich-176	137	25	way	way	NOUN
biomedich-176	137	26	to	to	PART
biomedich-176	137	27	improve	improve	VERB
biomedich-176	137	28	mapping	mapping	NOUN
biomedich-176	137	29	resolution	resolution	NOUN
biomedich-176	137	30	.	.	PUNCT
biomedich-176	138	1	postnatal	postnatal	ADJ
biomedich-176	138	2	chromosomal	chromosomal	ADJ
biomedich-176	138	3	array	array	NOUN
biomedich-176	138	4	techniques	technique	NOUN
biomedich-176	138	5	have	have	VERB
biomedich-176	138	6	far	far	ADV
biomedich-176	138	7	higher	high	ADJ
biomedich-176	138	8	diagnostic	diagnostic	ADJ
biomedich-176	138	9	results	result	NOUN
biomedich-176	138	10	(	(	PUNCT
biomedich-176	138	11	15	15	NUM
biomedich-176	138	12	-	-	SYM
biomedich-176	138	13	20	20	NUM
biomedich-176	138	14	per	per	ADP
biomedich-176	138	15	cent	cent	NOUN
biomedich-176	138	16	)	)	PUNCT
biomedich-176	138	17	than	than	ADP
biomedich-176	138	18	g	g	NOUN
biomedich-176	138	19	-	-	PUNCT
biomedich-176	138	20	banded	band	VERB
biomedich-176	138	21	karyotyping	karyotyping	NOUN
biomedich-176	138	22	does	do	VERB
biomedich-176	138	23	for	for	ADP
biomedich-176	138	24	genetic	genetic	ADJ
biomedich-176	138	25	testing	testing	NOUN
biomedich-176	138	26	of	of	ADP
biomedich-176	138	27	people	people	NOUN
biomedich-176	138	28	with	with	ADP
biomedich-176	138	29	unexplained	unexplained	ADJ
biomedich-176	138	30	developmental	developmental	ADJ
biomedich-176	138	31	delay	delay	NOUN
biomedich-176	138	32	,	,	PUNCT
biomedich-176	138	33	intellectual	intellectual	ADJ
biomedich-176	138	34	impairment	impairment	NOUN
biomedich-176	138	35	,	,	PUNCT
biomedich-176	138	36	autism	autism	NOUN
biomedich-176	138	37	,	,	PUNCT
biomedich-176	138	38	or	or	CCONJ
biomedich-176	138	39	other	other	ADJ
biomedich-176	138	40	congenital	congenital	ADJ
biomedich-176	138	41	abnormalities	abnormality	NOUN
biomedich-176	138	42	,	,	PUNCT
biomedich-176	138	43	as	as	ADP
biomedich-176	138	44	the	the	DET
biomedich-176	138	45	first	first	ADJ
biomedich-176	138	46	-	-	PUNCT
biomedich-176	138	47	tier	tier	NOUN
biomedich-176	138	48	cytogenetic	cytogenetic	ADJ
biomedich-176	138	49	diagnostic	diagnostic	ADJ
biomedich-176	138	50	test	test	NOUN
biomedich-176	138	51	for	for	ADP
biomedich-176	138	52	people	people	NOUN
biomedich-176	138	53	with	with	ADP
biomedich-176	138	54	these	these	DET
biomedich-176	138	55	diseases	disease	NOUN
biomedich-176	138	56	,	,	PUNCT
biomedich-176	138	57	the	the	DET
biomedich-176	138	58	international	international	ADJ
biomedich-176	138	59	standards	standard	NOUN
biomedich-176	138	60	for	for	ADP
biomedich-176	138	61	cytogenomic	cytogenomic	ADJ
biomedich-176	138	62	array	array	PROPN
biomedich-176	138	63	consortium	consortium	NOUN
biomedich-176	138	64	recommends	recommend	VERB
biomedich-176	138	65	it	it	PRON
biomedich-176	138	66	(	(	PUNCT
biomedich-176	138	67	lee	lee	PROPN
biomedich-176	138	68	et	et	PROPN
biomedich-176	138	69	al	al	PROPN
biomedich-176	138	70	.	.	PROPN
biomedich-176	138	71	,2012	,2012	PROPN
biomedich-176	138	72	)	)	PUNCT
biomedich-176	138	73	.	.	PUNCT
biomedich-176	139	1	the	the	DET
biomedich-176	139	2	genotyping	genotyping	NOUN
biomedich-176	139	3	of	of	ADP
biomedich-176	139	4	metastatic	metastatic	ADJ
biomedich-176	139	5	samples	sample	NOUN
biomedich-176	139	6	,	,	PUNCT
biomedich-176	139	7	primarily	primarily	ADV
biomedich-176	139	8	focused	focus	VERB
biomedich-176	139	9	on	on	ADP
biomedich-176	139	10	array	array	NOUN
biomedich-176	139	11	-	-	PUNCT
biomedich-176	139	12	based	base	VERB
biomedich-176	139	13	comparative	comparative	ADJ
biomedich-176	139	14	genomic	genomic	NOUN
biomedich-176	139	15	hybridization	hybridization	NOUN
biomedich-176	139	16	(	(	PUNCT
biomedich-176	139	17	acgh	acgh	NOUN
biomedich-176	139	18	)	)	PUNCT
biomedich-176	139	19	and	and	CCONJ
biomedich-176	139	20	next	next	ADJ
biomedich-176	139	21	-	-	PUNCT
biomedich-176	139	22	generation	generation	NOUN
biomedich-176	139	23	sequencing	sequencing	NOUN
biomedich-176	139	24	,	,	PUNCT
biomedich-176	139	25	is	be	AUX
biomedich-176	139	26	the	the	DET
biomedich-176	139	27	growth	growth	NOUN
biomedich-176	139	28	of	of	ADP
biomedich-176	139	29	targeted	target	VERB
biomedich-176	139	30	therapies	therapy	NOUN
biomedich-176	139	31	and	and	CCONJ
biomedich-176	139	32	the	the	DET
biomedich-176	139	33	emergence	emergence	NOUN
biomedich-176	139	34	of	of	ADP
biomedich-176	139	35	personalized	personalized	ADJ
biomedich-176	139	36	medicine	medicine	NOUN
biomedich-176	139	37	(	(	PUNCT
biomedich-176	139	38	ngs	ng	NOUN
biomedich-176	139	39	)	)	PUNCT
biomedich-176	139	40	,	,	PUNCT
biomedich-176	139	41	another	another	DET
biomedich-176	139	42	solution	solution	NOUN
biomedich-176	139	43	to	to	ADP
biomedich-176	139	44	resolving	resolve	VERB
biomedich-176	139	45	acgh	acgh	NOUN
biomedich-176	139	46	's	's	PART
biomedich-176	139	47	drawbacks	drawback	NOUN
biomedich-176	139	48	,	,	PUNCT
biomedich-176	139	49	such	such	ADJ
biomedich-176	139	50	as	as	ADP
biomedich-176	139	51	the	the	DET
biomedich-176	139	52	repeat	repeat	NOUN
biomedich-176	139	53	-	-	PUNCT
biomedich-176	139	54	rich	rich	ADJ
biomedich-176	139	55	regions	region	NOUN
biomedich-176	139	56	,	,	PUNCT
biomedich-176	139	57	is	be	AUX
biomedich-176	139	58	next	next	ADJ
biomedich-176	139	59	-	-	PUNCT
biomedich-176	139	60	generation	generation	NOUN
biomedich-176	139	61	sequencing	sequencing	NOUN
biomedich-176	139	62	.	.	PUNCT
biomedich-176	140	1	the	the	DET
biomedich-176	140	2	genomic	genomic	ADJ
biomedich-176	140	3	analysis	analysis	NOUN
biomedich-176	140	4	should	should	AUX
biomedich-176	140	5	be	be	AUX
biomedich-176	140	6	paired	pair	VERB
biomedich-176	140	7	with	with	ADP
biomedich-176	140	8	expression	expression	NOUN
biomedich-176	140	9	analysis	analysis	NOUN
biomedich-176	140	10	to	to	PART
biomedich-176	140	11	elucidate	elucidate	VERB
biomedich-176	140	12	individual	individual	ADJ
biomedich-176	140	13	genes	gene	NOUN
biomedich-176	140	14	related	relate	VERB
biomedich-176	140	15	to	to	ADP
biomedich-176	140	16	breast	breast	NOUN
biomedich-176	140	17	cancer	cancer	NOUN
biomedich-176	140	18	development	development	NOUN
biomedich-176	140	19	and	and	CCONJ
biomedich-176	140	20	progression	progression	NOUN
biomedich-176	140	21	.	.	PUNCT
biomedich-176	141	1	identification	identification	NOUN
biomedich-176	141	2	of	of	ADP
biomedich-176	141	3	new	new	ADJ
biomedich-176	141	4	molecular	molecular	ADJ
biomedich-176	141	5	targets	target	NOUN
biomedich-176	141	6	for	for	ADP
biomedich-176	141	7	breast	breast	NOUN
biomedich-176	141	8	cancer	cancer	NOUN
biomedich-176	141	9	eradication	eradication	NOUN
biomedich-176	141	10	will	will	AUX
biomedich-176	141	11	contribute	contribute	VERB
biomedich-176	141	12	to	to	ADP
biomedich-176	141	13	the	the	DET
biomedich-176	141	14	elucidation	elucidation	NOUN
biomedich-176	141	15	of	of	ADP
biomedich-176	141	16	the	the	DET
biomedich-176	141	17	functions	function	NOUN
biomedich-176	141	18	of	of	ADP
biomedich-176	141	19	the	the	DET
biomedich-176	141	20	affected	affected	ADJ
biomedich-176	141	21	genes	gene	NOUN
biomedich-176	141	22	(	(	PUNCT
biomedich-176	141	23	ueno	ueno	PROPN
biomedich-176	141	24	et	et	PROPN
biomedich-176	141	25	al	al	PROPN
biomedich-176	141	26	.	.	PROPN
biomedich-176	141	27	,	,	PUNCT
biomedich-176	141	28	2012	2012	NUM
biomedich-176	141	29	)	)	PUNCT
biomedich-176	141	30	.	.	PUNCT
biomedich-176	142	1	figure	figure	NOUN
biomedich-176	142	2	5	5	NUM
biomedich-176	142	3	.	.	PUNCT
biomedich-176	143	1	the	the	DET
biomedich-176	143	2	photomicrograph	photomicrograph	NOUN
biomedich-176	143	3	of	of	ADP
biomedich-176	143	4	fluorescence	fluorescence	NOUN
biomedich-176	143	5	shows	show	VERB
biomedich-176	143	6	the	the	DET
biomedich-176	143	7	effects	effect	NOUN
biomedich-176	143	8	of	of	ADP
biomedich-176	143	9	comparative	comparative	ADJ
biomedich-176	143	10	genome	genome	NOUN
biomedich-176	143	11	hybridization	hybridization	NOUN
biomedich-176	143	12	of	of	ADP
biomedich-176	143	13	invasive	invasive	ADJ
biomedich-176	143	14	ductal	ductal	ADJ
biomedich-176	143	15	carcinoma	carcinoma	NOUN
biomedich-176	143	16	tissue	tissue	NOUN
biomedich-176	143	17	.	.	PUNCT
biomedich-176	144	1	(	(	PUNCT
biomedich-176	144	2	a	a	X
biomedich-176	144	3	)	)	PUNCT
biomedich-176	144	4	tumour	tumour	NOUN
biomedich-176	144	5	tissue	tissue	NOUN
biomedich-176	144	6	extracted	extract	VERB
biomedich-176	144	7	dna	dna	NOUN
biomedich-176	144	8	was	be	AUX
biomedich-176	144	9	labelled	label	VERB
biomedich-176	144	10	green	green	ADJ
biomedich-176	144	11	,	,	PUNCT
biomedich-176	144	12	and	and	CCONJ
biomedich-176	144	13	(	(	PUNCT
biomedich-176	144	14	b	b	NOUN
biomedich-176	144	15	)	)	PUNCT
biomedich-176	144	16	natural	natural	ADJ
biomedich-176	144	17	reference	reference	NOUN
biomedich-176	144	18	dna	dna	NOUN
biomedich-176	144	19	was	be	AUX
biomedich-176	144	20	labelled	label	VERB
biomedich-176	144	21	red	red	ADJ
biomedich-176	144	22	.	.	PUNCT
biomedich-176	145	1	(	(	PUNCT
biomedich-176	145	2	c	c	X
biomedich-176	145	3	)	)	PUNCT
biomedich-176	145	4	the	the	DET
biomedich-176	145	5	chromosome	chromosome	NOUN
biomedich-176	145	6	of	of	ADP
biomedich-176	145	7	the	the	DET
biomedich-176	145	8	regular	regular	ADJ
biomedich-176	145	9	metaphase	metaphase	NOUN
biomedich-176	145	10	was	be	AUX
biomedich-176	145	11	counterstained	counterstaine	VERB
biomedich-176	145	12	blue	blue	ADJ
biomedich-176	145	13	with	with	ADP
biomedich-176	145	14	dapi	dapi	PROPN
biomedich-176	145	15	.	.	PUNCT
biomedich-176	146	1	(	(	PUNCT
biomedich-176	146	2	d	d	X
biomedich-176	146	3	)	)	PUNCT
biomedich-176	146	4	tumour	tumour	NOUN
biomedich-176	146	5	and	and	CCONJ
biomedich-176	146	6	normal	normal	ADJ
biomedich-176	146	7	dna	dna	NOUN
biomedich-176	146	8	have	have	AUX
biomedich-176	146	9	been	be	AUX
biomedich-176	146	10	hybridized	hybridize	VERB
biomedich-176	146	11	to	to	ADP
biomedich-176	146	12	the	the	DET
biomedich-176	146	13	normal	normal	ADJ
biomedich-176	146	14	chromosome	chromosome	NOUN
biomedich-176	146	15	of	of	ADP
biomedich-176	146	16	the	the	DET
biomedich-176	146	17	metaphase	metaphase	NOUN
biomedich-176	146	18	.	.	PUNCT
biomedich-176	147	1	there	there	PRON
biomedich-176	147	2	is	be	VERB
biomedich-176	147	3	a	a	DET
biomedich-176	147	4	50	50	NUM
biomedich-176	147	5	biology	biology	NOUN
biomedich-176	147	6	,	,	PUNCT
biomedich-176	147	7	medicine	medicine	NOUN
biomedich-176	147	8	,	,	PUNCT
biomedich-176	147	9	&	&	CCONJ
biomedich-176	147	10	natural	natural	ADJ
biomedich-176	147	11	product	product	NOUN
biomedich-176	147	12	chemistry	chemistry	NOUN
biomedich-176	147	13	11	11	NUM
biomedich-176	147	14	(	(	PUNCT
biomedich-176	147	15	1	1	NUM
biomedich-176	147	16	)	)	PUNCT
biomedich-176	147	17	,	,	PUNCT
biomedich-176	147	18	2022	2022	NUM
biomedich-176	147	19	:	:	PUNCT
biomedich-176	147	20	45	45	NUM
biomedich-176	147	21	-	-	SYM
biomedich-176	147	22	54	54	NUM
biomedich-176	147	23	predominantly	predominantly	ADV
biomedich-176	147	24	green	green	ADJ
biomedich-176	147	25	colour	colour	NOUN
biomedich-176	147	26	in	in	ADP
biomedich-176	147	27	chromosomal	chromosomal	ADJ
biomedich-176	147	28	regions	region	NOUN
biomedich-176	147	29	,	,	PUNCT
biomedich-176	147	30	which	which	PRON
biomedich-176	147	31	were	be	AUX
biomedich-176	147	32	overrepresented	overrepresente	VERB
biomedich-176	147	33	in	in	ADP
biomedich-176	147	34	the	the	DET
biomedich-176	147	35	tumour	tumour	NOUN
biomedich-176	147	36	,	,	PUNCT
biomedich-176	147	37	while	while	SCONJ
biomedich-176	147	38	regions	region	NOUN
biomedich-176	147	39	with	with	ADP
biomedich-176	147	40	deletions	deletion	NOUN
biomedich-176	147	41	in	in	ADP
biomedich-176	147	42	the	the	DET
biomedich-176	147	43	tumour	tumour	NOUN
biomedich-176	147	44	show	show	NOUN
biomedich-176	147	45	a	a	DET
biomedich-176	147	46	predominantly	predominantly	ADV
biomedich-176	147	47	red	red	ADJ
biomedich-176	147	48	colour	colour	NOUN
biomedich-176	147	49	.	.	PUNCT
biomedich-176	148	1	the	the	DET
biomedich-176	148	2	overlap	overlap	NOUN
biomedich-176	148	3	reflects	reflect	VERB
biomedich-176	148	4	the	the	DET
biomedich-176	148	5	ratio	ratio	NOUN
biomedich-176	148	6	of	of	ADP
biomedich-176	148	7	changes	change	NOUN
biomedich-176	148	8	in	in	ADP
biomedich-176	148	9	the	the	DET
biomedich-176	148	10	copy	copy	NOUN
biomedich-176	148	11	number	number	NOUN
biomedich-176	148	12	between	between	ADP
biomedich-176	148	13	the	the	DET
biomedich-176	148	14	tumour	tumour	NOUN
biomedich-176	148	15	and	and	CCONJ
biomedich-176	148	16	the	the	DET
biomedich-176	148	17	dna	dna	PROPN
biomedich-176	148	18	control	control	NOUN
biomedich-176	148	19	(	(	PUNCT
biomedich-176	148	20	zhang	zhang	PROPN
biomedich-176	148	21	et	et	PROPN
biomedich-176	148	22	al	al	PROPN
biomedich-176	148	23	.	.	PROPN
biomedich-176	148	24	,	,	PUNCT
biomedich-176	148	25	2015	2015	NUM
biomedich-176	148	26	)	)	PUNCT
biomedich-176	148	27	.	.	PUNCT
biomedich-176	149	1	comparative	comparative	ADJ
biomedich-176	149	2	classical	classical	ADJ
biomedich-176	149	3	cytogenetic	cytogenetic	ADJ
biomedich-176	149	4	tools	tool	NOUN
biomedich-176	149	5	with	with	ADP
biomedich-176	149	6	fluorescence	fluorescence	NOUN
biomedich-176	149	7	in	in	ADP
biomedich-176	149	8	situ	situ	ADJ
biomedich-176	149	9	hybridization	hybridization	NOUN
biomedich-176	149	10	hybridization	hybridization	NOUN
biomedich-176	149	11	of	of	ADP
biomedich-176	149	12	fluorescence	fluorescence	NOUN
biomedich-176	149	13	in	in	ADP
biomedich-176	149	14	situ	situ	NOUN
biomedich-176	149	15	(	(	PUNCT
biomedich-176	149	16	fish	fish	NOUN
biomedich-176	149	17	)	)	PUNCT
biomedich-176	149	18	enables	enable	VERB
biomedich-176	149	19	cytogenetic	cytogenetic	ADJ
biomedich-176	149	20	analyses	analysis	NOUN
biomedich-176	149	21	of	of	ADP
biomedich-176	149	22	primary	primary	ADJ
biomedich-176	149	23	tumours	tumour	NOUN
biomedich-176	149	24	without	without	ADP
biomedich-176	149	25	culture	culture	NOUN
biomedich-176	149	26	(	(	PUNCT
biomedich-176	149	27	thompson	thompson	NOUN
biomedich-176	149	28	and	and	CCONJ
biomedich-176	149	29	gray	gray	ADJ
biomedich-176	149	30	1993	1993	NUM
biomedich-176	149	31	)	)	PUNCT
biomedich-176	149	32	.	.	PUNCT
biomedich-176	150	1	in	in	ADP
biomedich-176	150	2	the	the	DET
biomedich-176	150	3	identification	identification	NOUN
biomedich-176	150	4	and	and	CCONJ
biomedich-176	150	5	evaluation	evaluation	NOUN
biomedich-176	150	6	of	of	ADP
biomedich-176	150	7	human	human	ADJ
biomedich-176	150	8	malignancies	malignancy	NOUN
biomedich-176	150	9	,	,	PUNCT
biomedich-176	150	10	one	one	NUM
biomedich-176	150	11	of	of	ADP
biomedich-176	150	12	the	the	DET
biomedich-176	150	13	greatest	great	ADJ
biomedich-176	150	14	impacts	impact	NOUN
biomedich-176	150	15	has	have	AUX
biomedich-176	150	16	been	be	AUX
biomedich-176	150	17	in	in	ADP
biomedich-176	150	18	the	the	DET
biomedich-176	150	19	non	non	ADJ
biomedich-176	150	20	-	-	ADJ
biomedich-176	150	21	dividing	dividing	ADJ
biomedich-176	150	22	interphase	interphase	NOUN
biomedich-176	150	23	nucleus	nucleus	NOUN
biomedich-176	150	24	,	,	PUNCT
biomedich-176	150	25	chromosome	chromosome	NOUN
biomedich-176	150	26	translocations	translocation	NOUN
biomedich-176	150	27	,	,	PUNCT
biomedich-176	150	28	deletions	deletion	NOUN
biomedich-176	150	29	,	,	PUNCT
biomedich-176	150	30	amplification	amplification	NOUN
biomedich-176	150	31	of	of	ADP
biomedich-176	150	32	particular	particular	ADJ
biomedich-176	150	33	genes	gene	NOUN
biomedich-176	150	34	,	,	PUNCT
biomedich-176	150	35	and	and	CCONJ
biomedich-176	150	36	chromosome	chromosome	NOUN
biomedich-176	150	37	number	number	NOUN
biomedich-176	150	38	changes	change	NOUN
biomedich-176	150	39	identified	identify	VERB
biomedich-176	150	40	using	use	VERB
biomedich-176	150	41	probes	probe	NOUN
biomedich-176	150	42	ranging	range	VERB
biomedich-176	150	43	from	from	ADP
biomedich-176	150	44	whole	whole	ADJ
biomedich-176	150	45	chromosome	chromosome	NOUN
biomedich-176	150	46	'	'	PUNCT
biomedich-176	150	47	paints	paint	NOUN
biomedich-176	150	48	'	'	PUNCT
biomedich-176	150	49	to	to	ADP
biomedich-176	150	50	individual	individual	ADJ
biomedich-176	150	51	gene	gene	NOUN
biomedich-176	150	52	-	-	PUNCT
biomedich-176	150	53	specific	specific	ADJ
biomedich-176	150	54	probes	probe	NOUN
biomedich-176	150	55	.	.	PUNCT
biomedich-176	151	1	progress	progress	NOUN
biomedich-176	151	2	in	in	ADP
biomedich-176	151	3	fish	fish	NOUN
biomedich-176	151	4	technology	technology	NOUN
biomedich-176	151	5	has	have	AUX
biomedich-176	151	6	also	also	ADV
biomedich-176	151	7	benefited	benefit	VERB
biomedich-176	151	8	from	from	ADP
biomedich-176	151	9	gene	gene	NOUN
biomedich-176	151	10	mapping	mapping	NOUN
biomedich-176	151	11	(	(	PUNCT
biomedich-176	151	12	price	price	NOUN
biomedich-176	151	13	1993	1993	NUM
biomedich-176	151	14	)	)	PUNCT
biomedich-176	151	15	.	.	PUNCT
biomedich-176	152	1	in	in	ADP
biomedich-176	152	2	comparison	comparison	NOUN
biomedich-176	152	3	to	to	ADP
biomedich-176	152	4	the	the	DET
biomedich-176	152	5	methods	method	NOUN
biomedich-176	152	6	mentioned	mention	VERB
biomedich-176	152	7	previously	previously	ADV
biomedich-176	152	8	separate	separate	ADJ
biomedich-176	152	9	denaturation	denaturation	NOUN
biomedich-176	152	10	or	or	CCONJ
biomedich-176	152	11	proteinase	proteinase	NOUN
biomedich-176	152	12	k	k	PROPN
biomedich-176	152	13	digestion	digestion	NOUN
biomedich-176	152	14	changes	change	NOUN
biomedich-176	152	15	are	be	AUX
biomedich-176	152	16	not	not	PART
biomedich-176	152	17	needed	need	VERB
biomedich-176	152	18	for	for	ADP
biomedich-176	152	19	each	each	DET
biomedich-176	152	20	sample	sample	NOUN
biomedich-176	152	21	.	.	PUNCT
biomedich-176	153	1	this	this	DET
biomedich-176	153	2	technique	technique	NOUN
biomedich-176	153	3	allows	allow	VERB
biomedich-176	153	4	retrospective	retrospective	ADJ
biomedich-176	153	5	studies	study	NOUN
biomedich-176	153	6	of	of	ADP
biomedich-176	153	7	large	large	ADJ
biomedich-176	153	8	series	series	NOUN
biomedich-176	153	9	of	of	ADP
biomedich-176	153	10	tumors	tumor	NOUN
biomedich-176	153	11	and	and	CCONJ
biomedich-176	153	12	is	be	AUX
biomedich-176	153	13	also	also	ADV
biomedich-176	153	14	useful	useful	ADJ
biomedich-176	153	15	for	for	ADP
biomedich-176	153	16	the	the	DET
biomedich-176	153	17	routine	routine	ADJ
biomedich-176	153	18	diagnostic	diagnostic	ADJ
biomedich-176	153	19	use	use	NOUN
biomedich-176	153	20	of	of	ADP
biomedich-176	153	21	formalin	formalin	NOUN
biomedich-176	153	22	-	-	PUNCT
biomedich-176	153	23	fixed	fix	VERB
biomedich-176	153	24	material	material	NOUN
biomedich-176	153	25	to	to	PART
biomedich-176	153	26	apply	apply	VERB
biomedich-176	153	27	fish	fish	NOUN
biomedich-176	153	28	(	(	PUNCT
biomedich-176	153	29	hyytinen	hyytinen	NOUN
biomedich-176	153	30	et	et	PROPN
biomedich-176	153	31	al	al	PROPN
biomedich-176	153	32	.	.	PROPN
biomedich-176	153	33	,	,	PUNCT
biomedich-176	153	34	1994	1994	NUM
biomedich-176	153	35	)	)	PUNCT
biomedich-176	153	36	.	.	PUNCT
biomedich-176	154	1	the	the	DET
biomedich-176	154	2	fish	fish	NOUN
biomedich-176	154	3	technique	technique	NOUN
biomedich-176	154	4	also	also	ADV
biomedich-176	154	5	helped	help	VERB
biomedich-176	154	6	us	we	PRON
biomedich-176	154	7	determine	determine	VERB
biomedich-176	154	8	the	the	DET
biomedich-176	154	9	degree	degree	NOUN
biomedich-176	154	10	of	of	ADP
biomedich-176	154	11	amplification	amplification	NOUN
biomedich-176	154	12	and	and	CCONJ
biomedich-176	154	13	the	the	DET
biomedich-176	154	14	size	size	NOUN
biomedich-176	154	15	of	of	ADP
biomedich-176	154	16	the	the	DET
biomedich-176	154	17	intrachromosomal	intrachromosomal	ADJ
biomedich-176	154	18	amplified	amplify	VERB
biomedich-176	154	19	regions	region	NOUN
biomedich-176	154	20	at	at	ADP
biomedich-176	154	21	metaphase	metaphase	NOUN
biomedich-176	154	22	and	and	CCONJ
biomedich-176	154	23	interphase	interphase	NOUN
biomedich-176	154	24	(	(	PUNCT
biomedich-176	154	25	bar	bar	NOUN
biomedich-176	154	26	et	et	NOUN
biomedich-176	154	27	al	al	PROPN
biomedich-176	154	28	.	.	PROPN
biomedich-176	154	29	,	,	PUNCT
biomedich-176	154	30	1992	1992	NUM
biomedich-176	154	31	)	)	PUNCT
biomedich-176	154	32	.	.	PUNCT
biomedich-176	155	1	fluorescence	fluorescence	NOUN
biomedich-176	155	2	in	in	ADP
biomedich-176	155	3	situ	situ	ADJ
biomedich-176	155	4	hybridization	hybridization	NOUN
biomedich-176	155	5	(	(	PUNCT
biomedich-176	155	6	fish	fish	NOUN
biomedich-176	155	7	)	)	PUNCT
biomedich-176	155	8	is	be	AUX
biomedich-176	155	9	used	use	VERB
biomedich-176	155	10	in	in	ADP
biomedich-176	155	11	genetic	genetic	ADJ
biomedich-176	155	12	toxicology	toxicology	NOUN
biomedich-176	155	13	for	for	ADP
biomedich-176	155	14	the	the	DET
biomedich-176	155	15	study	study	NOUN
biomedich-176	155	16	of	of	ADP
biomedich-176	155	17	chromosome	chromosome	NOUN
biomedich-176	155	18	damage	damage	NOUN
biomedich-176	155	19	with	with	ADP
biomedich-176	155	20	improved	improved	ADJ
biomedich-176	155	21	efficiency	efficiency	NOUN
biomedich-176	155	22	and	and	CCONJ
biomedich-176	155	23	precision	precision	NOUN
biomedich-176	155	24	to	to	PART
biomedich-176	155	25	distinguish	distinguish	VERB
biomedich-176	155	26	certain	certain	ADJ
biomedich-176	155	27	forms	form	NOUN
biomedich-176	155	28	of	of	ADP
biomedich-176	155	29	chromosome	chromosome	NOUN
biomedich-176	155	30	aberrations	aberration	NOUN
biomedich-176	155	31	,	,	PUNCT
biomedich-176	155	32	in	in	ADP
biomedich-176	155	33	addition	addition	NOUN
biomedich-176	155	34	to	to	ADP
biomedich-176	155	35	classical	classical	ADJ
biomedich-176	155	36	cytogenetic	cytogenetic	ADJ
biomedich-176	155	37	methods	method	NOUN
biomedich-176	155	38	for	for	ADP
biomedich-176	155	39	scoring	score	VERB
biomedich-176	155	40	chromosomal	chromosomal	ADJ
biomedich-176	155	41	aberrations	aberration	NOUN
biomedich-176	155	42	(	(	PUNCT
biomedich-176	155	43	hovhannisyan	hovhannisyan	NOUN
biomedich-176	155	44	,	,	PUNCT
biomedich-176	155	45	2010	2010	NUM
biomedich-176	155	46	)	)	PUNCT
biomedich-176	155	47	.	.	PUNCT
biomedich-176	156	1	the	the	DET
biomedich-176	156	2	study	study	NOUN
biomedich-176	156	3	shows	show	VERB
biomedich-176	156	4	the	the	DET
biomedich-176	156	5	utility	utility	NOUN
biomedich-176	156	6	of	of	ADP
biomedich-176	156	7	a	a	DET
biomedich-176	156	8	combination	combination	NOUN
biomedich-176	156	9	of	of	ADP
biomedich-176	156	10	classical	classical	ADJ
biomedich-176	156	11	karyotyping	karyotyping	NOUN
biomedich-176	156	12	and	and	CCONJ
biomedich-176	156	13	fish	fish	NOUN
biomedich-176	156	14	to	to	PART
biomedich-176	156	15	determine	determine	VERB
biomedich-176	156	16	the	the	DET
biomedich-176	156	17	chromosome	chromosome	NOUN
biomedich-176	156	18	origin	origin	NOUN
biomedich-176	156	19	of	of	ADP
biomedich-176	156	20	doubleminute	doubleminute	NOUN
biomedich-176	156	21	chromosome	chromosome	NOUN
biomedich-176	156	22	amplified	amplify	VERB
biomedich-176	156	23	dna	dna	PROPN
biomedich-176	156	24	sequences	sequence	NOUN
biomedich-176	156	25	in	in	ADP
biomedich-176	156	26	cancer	cancer	NOUN
biomedich-176	156	27	cells	cell	NOUN
biomedich-176	156	28	(	(	PUNCT
biomedich-176	156	29	giollan	giollan	VERB
biomedich-176	156	30	et	et	PROPN
biomedich-176	156	31	al	al	PROPN
biomedich-176	156	32	.	.	PROPN
biomedich-176	156	33	,1996	,1996	PROPN
biomedich-176	156	34	)	)	PUNCT
biomedich-176	156	35	.	.	PUNCT
biomedich-176	157	1	fish	fish	NOUN
biomedich-176	157	2	identified	identify	VERB
biomedich-176	157	3	cells	cell	NOUN
biomedich-176	157	4	with	with	ADP
biomedich-176	157	5	clonal	clonal	ADJ
biomedich-176	157	6	chromosomal	chromosomal	ADJ
biomedich-176	157	7	defects	defect	NOUN
biomedich-176	157	8	with	with	ADP
biomedich-176	157	9	rates	rate	NOUN
biomedich-176	157	10	of	of	ADP
biomedich-176	157	11	aneuploidy	aneuploidy	ADJ
biomedich-176	157	12	ranging	range	VERB
biomedich-176	157	13	from	from	ADP
biomedich-176	157	14	6	6	NUM
biomedich-176	157	15	%	%	NOUN
biomedich-176	157	16	to	to	ADP
biomedich-176	157	17	92	92	NUM
biomedich-176	157	18	%	%	NOUN
biomedich-176	157	19	(	(	PUNCT
biomedich-176	157	20	median	median	NOUN
biomedich-176	157	21	59	59	NUM
biomedich-176	157	22	%	%	NOUN
biomedich-176	157	23	)	)	PUNCT
biomedich-176	157	24	.	.	PUNCT
biomedich-176	158	1	in	in	ADP
biomedich-176	158	2	addition	addition	NOUN
biomedich-176	158	3	,	,	PUNCT
biomedich-176	158	4	there	there	PRON
biomedich-176	158	5	was	be	VERB
biomedich-176	158	6	a	a	DET
biomedich-176	158	7	gain	gain	NOUN
biomedich-176	158	8	of	of	ADP
biomedich-176	158	9	centromeric	centromeric	ADJ
biomedich-176	158	10	signals	signal	NOUN
biomedich-176	158	11	for	for	ADP
biomedich-176	158	12	chromosome	chromosome	NOUN
biomedich-176	158	13	11	11	NUM
biomedich-176	158	14	,	,	PUNCT
biomedich-176	158	15	most	most	ADV
biomedich-176	158	16	likely	likely	ADV
biomedich-176	158	17	corresponding	correspond	VERB
biomedich-176	158	18	to	to	ADP
biomedich-176	158	19	hyperdiploid	hyperdiploid	VERB
biomedich-176	158	20	;	;	PUNCT
biomedich-176	158	21	aberrations	aberration	NOUN
biomedich-176	158	22	of	of	ADP
biomedich-176	158	23	chromosome	chromosome	NOUN
biomedich-176	158	24	17	17	NUM
biomedich-176	158	25	in	in	ADP
biomedich-176	158	26	specimens	specimen	NOUN
biomedich-176	158	27	from	from	ADP
biomedich-176	158	28	26	26	NUM
biomedich-176	158	29	patients	patient	NOUN
biomedich-176	158	30	(	(	PUNCT
biomedich-176	158	31	87	87	NUM
biomedich-176	158	32	%	%	NOUN
biomedich-176	158	33	)	)	PUNCT
biomedich-176	158	34	were	be	AUX
biomedich-176	158	35	hyperploid	hyperploid	VERB
biomedich-176	158	36	as	as	ADV
biomedich-176	158	37	well	well	ADV
biomedich-176	158	38	;	;	PUNCT
biomedich-176	158	39	however	however	ADV
biomedich-176	158	40	,	,	PUNCT
biomedich-176	158	41	four	four	NUM
biomedich-176	158	42	cases	case	NOUN
biomedich-176	158	43	(	(	PUNCT
biomedich-176	158	44	13	13	NUM
biomedich-176	158	45	%	%	NOUN
biomedich-176	158	46	)	)	PUNCT
biomedich-176	158	47	showed	show	VERB
biomedich-176	158	48	loss	loss	NOUN
biomedich-176	158	49	of	of	ADP
biomedich-176	158	50	chromosome	chromosome	NOUN
biomedich-176	158	51	17	17	NUM
biomedich-176	158	52	centromeres	centromere	NOUN
biomedich-176	158	53	(	(	PUNCT
biomedich-176	158	54	fiegl	fiegl	NOUN
biomedich-176	158	55	et	et	PROPN
biomedich-176	158	56	al	al	PROPN
biomedich-176	158	57	.	.	PROPN
biomedich-176	158	58	,	,	PUNCT
biomedich-176	158	59	1995	1995	NUM
biomedich-176	158	60	)	)	PUNCT
biomedich-176	158	61	.	.	PUNCT
biomedich-176	159	1	modern	modern	ADJ
biomedich-176	159	2	high	high	ADJ
biomedich-176	159	3	-	-	PUNCT
biomedich-176	159	4	throughput	throughput	NOUN
biomedich-176	159	5	techniques	technique	NOUN
biomedich-176	159	6	affect	affect	VERB
biomedich-176	159	7	research	research	NOUN
biomedich-176	159	8	to	to	PART
biomedich-176	159	9	classify	classify	VERB
biomedich-176	159	10	new	new	ADJ
biomedich-176	159	11	genomic	genomic	ADJ
biomedich-176	159	12	regions	region	NOUN
biomedich-176	159	13	associated	associate	VERB
biomedich-176	159	14	with	with	ADP
biomedich-176	159	15	tumours	tumours	PROPN
biomedich-176	159	16	(	(	PUNCT
biomedich-176	159	17	liehr	liehr	NOUN
biomedich-176	159	18	et	et	PROPN
biomedich-176	159	19	al	al	PROPN
biomedich-176	159	20	.	.	PROPN
biomedich-176	159	21	,	,	PUNCT
biomedich-176	159	22	2015	2015	NUM
biomedich-176	159	23	)	)	PUNCT
biomedich-176	159	24	.	.	PUNCT
biomedich-176	160	1	in	in	ADP
biomedich-176	160	2	correlating	correlate	VERB
biomedich-176	160	3	karyotype	karyotype	NOUN
biomedich-176	160	4	abnormalities	abnormality	NOUN
biomedich-176	160	5	with	with	ADP
biomedich-176	160	6	diagnosis	diagnosis	NOUN
biomedich-176	160	7	,	,	PUNCT
biomedich-176	160	8	prognosis	prognosis	NOUN
biomedich-176	160	9	,	,	PUNCT
biomedich-176	160	10	and	and	CCONJ
biomedich-176	160	11	response	response	NOUN
biomedich-176	160	12	to	to	ADP
biomedich-176	160	13	therapy	therapy	NOUN
biomedich-176	160	14	in	in	ADP
biomedich-176	160	15	haematological	haematological	ADJ
biomedich-176	160	16	neoplasias	neoplasia	NOUN
biomedich-176	160	17	,	,	PUNCT
biomedich-176	160	18	classical	classical	ADJ
biomedich-176	160	19	cytogenetics	cytogenetic	NOUN
biomedich-176	160	20	described	describe	VERB
biomedich-176	160	21	by	by	ADP
biomedich-176	160	22	chromosomal	chromosomal	ADJ
biomedich-176	160	23	banding	banding	NOUN
biomedich-176	160	24	techniques	technique	NOUN
biomedich-176	160	25	has	have	AUX
biomedich-176	160	26	been	be	AUX
biomedich-176	160	27	effective	effective	ADJ
biomedich-176	160	28	.	.	PUNCT
biomedich-176	161	1	such	such	ADJ
biomedich-176	161	2	approaches	approach	NOUN
biomedich-176	161	3	,	,	PUNCT
biomedich-176	161	4	however	however	ADV
biomedich-176	161	5	,	,	PUNCT
biomedich-176	161	6	require	require	VERB
biomedich-176	161	7	a	a	DET
biomedich-176	161	8	high	high	ADJ
biomedich-176	161	9	cell	cell	NOUN
biomedich-176	161	10	division	division	NOUN
biomedich-176	161	11	rate	rate	NOUN
biomedich-176	161	12	and	and	CCONJ
biomedich-176	161	13	good	good	ADJ
biomedich-176	161	14	chromosomal	chromosomal	ADJ
biomedich-176	161	15	morphology	morphology	NOUN
biomedich-176	161	16	,	,	PUNCT
biomedich-176	161	17	which	which	PRON
biomedich-176	161	18	pose	pose	VERB
biomedich-176	161	19	challenges	challenge	NOUN
biomedich-176	161	20	for	for	ADP
biomedich-176	161	21	cytogeneticists	cytogeneticist	NOUN
biomedich-176	161	22	,	,	PUNCT
biomedich-176	161	23	and	and	CCONJ
biomedich-176	161	24	a	a	DET
biomedich-176	161	25	long	long	ADJ
biomedich-176	161	26	period	period	NOUN
biomedich-176	161	27	of	of	ADP
biomedich-176	161	28	testing	testing	NOUN
biomedich-176	161	29	and	and	CCONJ
biomedich-176	161	30	study	study	NOUN
biomedich-176	161	31	,	,	PUNCT
biomedich-176	161	32	which	which	PRON
biomedich-176	161	33	is	be	AUX
biomedich-176	161	34	typically	typically	ADV
biomedich-176	161	35	a	a	DET
biomedich-176	161	36	challenge	challenge	NOUN
biomedich-176	161	37	for	for	ADP
biomedich-176	161	38	doctors	doctor	NOUN
biomedich-176	161	39	(	(	PUNCT
biomedich-176	161	40	varella	varella	NOUN
biomedich-176	161	41	,	,	PUNCT
biomedich-176	161	42	2003	2003	NUM
biomedich-176	161	43	)	)	PUNCT
biomedich-176	161	44	.	.	PUNCT
biomedich-176	162	1	also	also	ADV
biomedich-176	162	2	,	,	PUNCT
biomedich-176	162	3	fish	fish	NOUN
biomedich-176	162	4	is	be	AUX
biomedich-176	162	5	considered	consider	VERB
biomedich-176	162	6	safer	safe	ADJ
biomedich-176	162	7	and	and	CCONJ
biomedich-176	162	8	has	have	VERB
biomedich-176	162	9	the	the	DET
biomedich-176	162	10	added	add	VERB
biomedich-176	162	11	benefit	benefit	NOUN
biomedich-176	162	12	of	of	ADP
biomedich-176	162	13	using	use	VERB
biomedich-176	162	14	several	several	ADJ
biomedich-176	162	15	fluorochromes	fluorochrome	NOUN
biomedich-176	162	16	to	to	PART
biomedich-176	162	17	differentiate	differentiate	VERB
biomedich-176	162	18	between	between	ADP
biomedich-176	162	19	different	different	ADJ
biomedich-176	162	20	targets	target	NOUN
biomedich-176	162	21	simultaneously	simultaneously	ADV
biomedich-176	162	22	(	(	PUNCT
biomedich-176	162	23	bartlett	bartlett	PROPN
biomedich-176	162	24	,	,	PUNCT
biomedich-176	162	25	2004	2004	NUM
biomedich-176	162	26	)	)	PUNCT
biomedich-176	162	27	.	.	PUNCT
biomedich-176	163	1	these	these	DET
biomedich-176	163	2	approaches	approach	NOUN
biomedich-176	163	3	range	range	VERB
biomedich-176	163	4	from	from	ADP
biomedich-176	163	5	dna	dna	PROPN
biomedich-176	163	6	fluorescence	fluorescence	NOUN
biomedich-176	163	7	in	in	ADP
biomedich-176	163	8	situ	situ	ADJ
biomedich-176	163	9	hybridization	hybridization	NOUN
biomedich-176	163	10	(	(	PUNCT
biomedich-176	163	11	fish)based	fish)base	VERB
biomedich-176	163	12	kilobase	kilobase	NOUN
biomedich-176	163	13	-	-	PUNCT
biomedich-176	163	14	level	level	NOUN
biomedich-176	163	15	resolution	resolution	NOUN
biomedich-176	163	16	imaging	imaging	NOUN
biomedich-176	163	17	approaches	approach	NOUN
biomedich-176	163	18	of	of	ADP
biomedich-176	163	19	individual	individual	ADJ
biomedich-176	163	20	cells	cell	NOUN
biomedich-176	163	21	to	to	ADP
biomedich-176	163	22	genome	genome	NOUN
biomedich-176	163	23	-	-	PUNCT
biomedich-176	163	24	wide	wide	ADJ
biomedich-176	163	25	sequencing	sequence	VERB
biomedich-176	163	26	strategies	strategy	NOUN
biomedich-176	163	27	that	that	PRON
biomedich-176	163	28	collect	collect	VERB
biomedich-176	163	29	nucleotide	nucleotide	NOUN
biomedich-176	163	30	-	-	PUNCT
biomedich-176	163	31	level	level	NOUN
biomedich-176	163	32	data	datum	NOUN
biomedich-176	163	33	from	from	ADP
biomedich-176	163	34	different	different	ADJ
biomedich-176	163	35	sample	sample	NOUN
biomedich-176	163	36	types	type	NOUN
biomedich-176	163	37	.	.	PUNCT
biomedich-176	164	1	in	in	ADP
biomedich-176	164	2	conjunction	conjunction	NOUN
biomedich-176	164	3	with	with	ADP
biomedich-176	164	4	the	the	DET
biomedich-176	164	5	combinatorial	combinatorial	ADJ
biomedich-176	164	6	use	use	NOUN
biomedich-176	164	7	of	of	ADP
biomedich-176	164	8	multiple	multiple	ADJ
biomedich-176	164	9	approaches	approach	NOUN
biomedich-176	164	10	,	,	PUNCT
biomedich-176	164	11	technical	technical	ADJ
biomedich-176	164	12	developments	development	NOUN
biomedich-176	164	13	have	have	AUX
biomedich-176	164	14	led	lead	VERB
biomedich-176	164	15	to	to	ADP
biomedich-176	164	16	new	new	ADJ
biomedich-176	164	17	rearrangement	rearrangement	ADJ
biomedich-176	164	18	groups	group	NOUN
biomedich-176	164	19	and	and	CCONJ
biomedich-176	164	20	mechanistic	mechanistic	ADJ
biomedich-176	164	21	insights	insight	NOUN
biomedich-176	164	22	into	into	ADP
biomedich-176	164	23	processes	process	NOUN
biomedich-176	164	24	that	that	PRON
biomedich-176	164	25	drive	drive	VERB
biomedich-176	164	26	structural	structural	ADJ
biomedich-176	164	27	changes	change	NOUN
biomedich-176	164	28	in	in	ADP
biomedich-176	164	29	the	the	DET
biomedich-176	164	30	human	human	ADJ
biomedich-176	164	31	genome	genome	NOUN
biomedich-176	164	32	(	(	PUNCT
biomedich-176	164	33	hu	hu	NOUN
biomedich-176	164	34	and	and	CCONJ
biomedich-176	164	35	ly	ly	ADP
biomedich-176	164	36	2020	2020	NUM
biomedich-176	164	37	)	)	PUNCT
biomedich-176	164	38	.	.	PUNCT
biomedich-176	165	1	fish	fish	NOUN
biomedich-176	165	2	and	and	CCONJ
biomedich-176	165	3	traditional	traditional	ADJ
biomedich-176	165	4	cytogenetic	cytogenetic	ADJ
biomedich-176	165	5	experiments	experiment	NOUN
biomedich-176	165	6	often	often	ADV
biomedich-176	165	7	offer	offer	VERB
biomedich-176	165	8	a	a	DET
biomedich-176	165	9	false	false	ADJ
biomedich-176	165	10	negative	negative	ADJ
biomedich-176	165	11	outcome	outcome	NOUN
biomedich-176	165	12	(	(	PUNCT
biomedich-176	165	13	alayed	alaye	VERB
biomedich-176	165	14	et	et	PROPN
biomedich-176	165	15	al	al	PROPN
biomedich-176	165	16	.	.	PROPN
biomedich-176	165	17	,	,	PUNCT
biomedich-176	165	18	2013	2013	NUM
biomedich-176	165	19	)	)	PUNCT
biomedich-176	165	20	.	.	PUNCT
biomedich-176	166	1	figure	figure	VERB
biomedich-176	166	2	6	6	NUM
biomedich-176	166	3	.	.	PUNCT
biomedich-176	167	1	schematic	schematic	ADJ
biomedich-176	167	2	diagram	diagram	NOUN
biomedich-176	167	3	of	of	ADP
biomedich-176	167	4	karyotyping	karyotyping	NOUN
biomedich-176	167	5	(	(	PUNCT
biomedich-176	167	6	qaisar	qaisar	PROPN
biomedich-176	167	7	and	and	CCONJ
biomedich-176	167	8	bhat	bhat	PROPN
biomedich-176	167	9	,	,	PUNCT
biomedich-176	167	10	2017	2017	NUM
biomedich-176	167	11	)	)	PUNCT
biomedich-176	167	12	.	.	PUNCT
biomedich-176	168	1	smail	smail	NOUN
biomedich-176	168	2	–	–	PUNCT
biomedich-176	168	3	the	the	DET
biomedich-176	168	4	roles	role	NOUN
biomedich-176	168	5	of	of	ADP
biomedich-176	168	6	the	the	DET
biomedich-176	168	7	fluorescent	fluorescent	NOUN
biomedich-176	168	8	in	in	ADP
biomedich-176	168	9	situ	situ	ADJ
biomedich-176	168	10	hybridization	hybridization	NOUN
biomedich-176	168	11	(	(	PUNCT
biomedich-176	168	12	fish	fish	NOUN
biomedich-176	168	13	)	)	PUNCT
biomedich-176	168	14	and	and	CCONJ
biomedich-176	168	15	…	…	PUNCT
biomedich-176	168	16	51	51	NUM
biomedich-176	168	17	figure	figure	NOUN
biomedich-176	168	18	7	7	NUM
biomedich-176	168	19	.	.	PUNCT
biomedich-176	169	1	the	the	DET
biomedich-176	169	2	concepts	concept	NOUN
biomedich-176	169	3	of	of	ADP
biomedich-176	169	4	in	in	ADP
biomedich-176	169	5	situ	situ	ADJ
biomedich-176	169	6	hybridization	hybridization	NOUN
biomedich-176	169	7	of	of	ADP
biomedich-176	169	8	fluorescence	fluorescence	NOUN
biomedich-176	169	9	.	.	PUNCT
biomedich-176	170	1	(	(	PUNCT
biomedich-176	170	2	a	a	X
biomedich-176	170	3	)	)	PUNCT
biomedich-176	170	4	a	a	DET
biomedich-176	170	5	dna	dna	NOUN
biomedich-176	170	6	probe	probe	NOUN
biomedich-176	170	7	and	and	CCONJ
biomedich-176	170	8	a	a	DET
biomedich-176	170	9	target	target	NOUN
biomedich-176	170	10	sequence	sequence	NOUN
biomedich-176	170	11	are	be	AUX
biomedich-176	170	12	the	the	DET
biomedich-176	170	13	basic	basic	ADJ
biomedich-176	170	14	elements	element	NOUN
biomedich-176	170	15	.	.	PUNCT
biomedich-176	171	1	(	(	PUNCT
biomedich-176	171	2	b	b	X
biomedich-176	171	3	)	)	PUNCT
biomedich-176	171	4	before	before	ADP
biomedich-176	171	5	hybridization	hybridization	NOUN
biomedich-176	171	6	,	,	PUNCT
biomedich-176	171	7	the	the	DET
biomedich-176	171	8	dna	dna	PROPN
biomedich-176	171	9	probe	probe	NOUN
biomedich-176	171	10	is	be	AUX
biomedich-176	171	11	indirectly	indirectly	ADV
biomedich-176	171	12	marked	mark	VERB
biomedich-176	171	13	with	with	ADP
biomedich-176	171	14	hapten	hapten	VERB
biomedich-176	171	15	(	(	PUNCT
biomedich-176	171	16	left	leave	VERB
biomedich-176	171	17	panel	panel	NOUN
biomedich-176	171	18	)	)	PUNCT
biomedich-176	171	19	or	or	CCONJ
biomedich-176	171	20	specifically	specifically	ADV
biomedich-176	171	21	marked	mark	VERB
biomedich-176	171	22	with	with	ADP
biomedich-176	171	23	hapten	hapten	NOUN
biomedich-176	171	24	(	(	PUNCT
biomedich-176	171	25	left	leave	VERB
biomedich-176	171	26	panel	panel	NOUN
biomedich-176	171	27	)	)	PUNCT
biomedich-176	171	28	by	by	ADP
biomedich-176	171	29	adding	add	VERB
biomedich-176	171	30	a	a	DET
biomedich-176	171	31	fluorophore	fluorophore	NOUN
biomedich-176	171	32	probe	probe	NOUN
biomedich-176	171	33	(	(	PUNCT
biomedich-176	171	34	right	right	ADJ
biomedich-176	171	35	panel	panel	NOUN
biomedich-176	171	36	)	)	PUNCT
biomedich-176	171	37	.	.	PUNCT
biomedich-176	172	1	(	(	PUNCT
biomedich-176	172	2	c	c	X
biomedich-176	172	3	)	)	PUNCT
biomedich-176	172	4	the	the	DET
biomedich-176	172	5	labelled	label	VERB
biomedich-176	172	6	probe	probe	NOUN
biomedich-176	172	7	and	and	CCONJ
biomedich-176	172	8	the	the	DET
biomedich-176	172	9	target	target	NOUN
biomedich-176	172	10	dna	dna	NOUN
biomedich-176	172	11	are	be	AUX
biomedich-176	172	12	denatured	denature	VERB
biomedich-176	172	13	to	to	PART
biomedich-176	172	14	yield	yield	VERB
biomedich-176	172	15	single	single	ADJ
biomedich-176	172	16	-	-	PUNCT
biomedich-176	172	17	stranded	strand	VERB
biomedich-176	172	18	dna	dna	NOUN
biomedich-176	172	19	.	.	PUNCT
biomedich-176	173	1	(	(	PUNCT
biomedich-176	173	2	d	d	X
biomedich-176	173	3	)	)	PUNCT
biomedich-176	173	4	they	they	PRON
biomedich-176	173	5	are	be	AUX
biomedich-176	173	6	then	then	ADV
biomedich-176	173	7	mixed	mix	VERB
biomedich-176	173	8	,	,	PUNCT
biomedich-176	173	9	which	which	PRON
biomedich-176	173	10	enables	enable	VERB
biomedich-176	173	11	complementary	complementary	ADJ
biomedich-176	173	12	dna	dna	PROPN
biomedich-176	173	13	sequences	sequence	NOUN
biomedich-176	173	14	to	to	PART
biomedich-176	173	15	be	be	AUX
biomedich-176	173	16	annealed	anneal	VERB
biomedich-176	173	17	.	.	PUNCT
biomedich-176	174	1	(	(	PUNCT
biomedich-176	174	2	e	e	X
biomedich-176	174	3	)	)	PUNCT
biomedich-176	174	4	if	if	SCONJ
biomedich-176	174	5	the	the	DET
biomedich-176	174	6	probe	probe	NOUN
biomedich-176	174	7	has	have	AUX
biomedich-176	174	8	been	be	AUX
biomedich-176	174	9	indirectly	indirectly	ADV
biomedich-176	174	10	labelled	label	VERB
biomedich-176	174	11	,	,	PUNCT
biomedich-176	174	12	the	the	DET
biomedich-176	174	13	visualization	visualization	NOUN
biomedich-176	174	14	of	of	ADP
biomedich-176	174	15	the	the	DET
biomedich-176	174	16	non	non	ADJ
biomedich-176	174	17	-	-	ADJ
biomedich-176	174	18	fluorescent	fluorescent	ADJ
biomedich-176	174	19	hapten	hapten	NOUN
biomedich-176	174	20	using	use	VERB
biomedich-176	174	21	an	an	DET
biomedich-176	174	22	enzymatic	enzymatic	ADJ
biomedich-176	174	23	or	or	CCONJ
biomedich-176	174	24	immunological	immunological	ADJ
biomedich-176	174	25	detection	detection	NOUN
biomedich-176	174	26	system	system	NOUN
biomedich-176	174	27	involves	involve	VERB
biomedich-176	174	28	an	an	DET
biomedich-176	174	29	additional	additional	ADJ
biomedich-176	174	30	step	step	NOUN
biomedich-176	174	31	.	.	PUNCT
biomedich-176	175	1	finally	finally	ADV
biomedich-176	175	2	,	,	PUNCT
biomedich-176	175	3	fluorescence	fluorescence	NOUN
biomedich-176	175	4	microscopy	microscopy	NOUN
biomedich-176	175	5	tests	test	VERB
biomedich-176	175	6	the	the	DET
biomedich-176	175	7	signals	signal	NOUN
biomedich-176	175	8	(	(	PUNCT
biomedich-176	175	9	shakoori	shakoori	NOUN
biomedich-176	175	10	,	,	PUNCT
biomedich-176	175	11	2017	2017	NUM
biomedich-176	175	12	)	)	PUNCT
biomedich-176	175	13	.	.	PUNCT
biomedich-176	176	1	limitation	limitation	NOUN
biomedich-176	176	2	of	of	ADP
biomedich-176	176	3	the	the	DET
biomedich-176	176	4	fluorescence	fluorescence	NOUN
biomedich-176	176	5	in	in	ADP
biomedich-176	176	6	situ	situ	ADJ
biomedich-176	176	7	hybridization	hybridization	NOUN
biomedich-176	176	8	while	while	SCONJ
biomedich-176	176	9	direct	direct	ADJ
biomedich-176	176	10	preparations	preparation	NOUN
biomedich-176	176	11	may	may	AUX
biomedich-176	176	12	be	be	AUX
biomedich-176	176	13	carried	carry	VERB
biomedich-176	176	14	out	out	ADP
biomedich-176	176	15	,	,	PUNCT
biomedich-176	176	16	cell	cell	NOUN
biomedich-176	176	17	culture	culture	NOUN
biomedich-176	176	18	is	be	AUX
biomedich-176	176	19	usually	usually	ADV
biomedich-176	176	20	needed	need	VERB
biomedich-176	176	21	(	(	PUNCT
biomedich-176	176	22	1	1	NUM
biomedich-176	176	23	-	-	SYM
biomedich-176	176	24	10	10	NUM
biomedich-176	176	25	days	day	NOUN
biomedich-176	176	26	)	)	PUNCT
biomedich-176	176	27	,	,	PUNCT
biomedich-176	176	28	complex	complex	ADJ
biomedich-176	176	29	karyotypes	karyotype	NOUN
biomedich-176	176	30	with	with	ADP
biomedich-176	176	31	suboptimal	suboptimal	ADJ
biomedich-176	176	32	morphology	morphology	NOUN
biomedich-176	176	33	may	may	AUX
biomedich-176	176	34	be	be	AUX
biomedich-176	176	35	encountered	encounter	VERB
biomedich-176	176	36	,	,	PUNCT
biomedich-176	176	37	submicroscopic	submicroscopic	ADJ
biomedich-176	176	38	or	or	CCONJ
biomedich-176	176	39	cryptic	cryptic	ADJ
biomedich-176	176	40	rearrangements	rearrangement	NOUN
biomedich-176	176	41	can	can	AUX
biomedich-176	176	42	result	result	VERB
biomedich-176	176	43	in	in	ADP
biomedich-176	176	44	a	a	DET
biomedich-176	176	45	false	false	ADJ
biomedich-176	176	46	-	-	PUNCT
biomedich-176	176	47	negative	negative	ADJ
biomedich-176	176	48	result	result	NOUN
biomedich-176	176	49	,	,	PUNCT
biomedich-176	176	50	normal	normal	ADJ
biomedich-176	176	51	karyotypes	karyotype	NOUN
biomedich-176	176	52	may	may	AUX
biomedich-176	176	53	be	be	AUX
biomedich-176	176	54	observed	observe	VERB
biomedich-176	176	55	after	after	ADP
biomedich-176	176	56	therapy	therapy	NOUN
biomedich-176	176	57	-	-	PUNCT
biomedich-176	176	58	induced	induce	VERB
biomedich-176	176	59	tumour	tumour	NOUN
biomedich-176	176	60	necrosis	necrosis	NOUN
biomedich-176	176	61	or	or	CCONJ
biomedich-176	176	62	overgrowth	overgrowth	NOUN
biomedich-176	176	63	of	of	ADP
biomedich-176	176	64	normal	normal	ADJ
biomedich-176	176	65	stromal	stromal	ADJ
biomedich-176	176	66	cell	cell	NOUN
biomedich-176	176	67	support	support	NOUN
biomedich-176	176	68	low	low	ADJ
biomedich-176	176	69	cell	cell	NOUN
biomedich-176	176	70	density	density	NOUN
biomedich-176	176	71	and	and	CCONJ
biomedich-176	176	72	the	the	DET
biomedich-176	176	73	release	release	NOUN
biomedich-176	176	74	of	of	ADP
biomedich-176	176	75	cells	cell	NOUN
biomedich-176	176	76	from	from	ADP
biomedich-176	176	77	the	the	DET
biomedich-176	176	78	bone	bone	NOUN
biomedich-176	176	79	matrix	matrix	NOUN
biomedich-176	176	80	are	be	AUX
biomedich-176	176	81	also	also	ADV
biomedich-176	176	82	issues	issue	NOUN
biomedich-176	176	83	with	with	ADP
biomedich-176	176	84	bone	bone	NOUN
biomedich-176	176	85	tumours	tumour	NOUN
biomedich-176	176	86	(	(	PUNCT
biomedich-176	176	87	bridge	bridge	NOUN
biomedich-176	176	88	,	,	PUNCT
biomedich-176	176	89	2008	2008	NUM
biomedich-176	176	90	)	)	PUNCT
biomedich-176	176	91	.	.	PUNCT
biomedich-176	177	1	there	there	PRON
biomedich-176	177	2	is	be	VERB
biomedich-176	177	3	still	still	ADV
biomedich-176	177	4	a	a	DET
biomedich-176	177	5	lack	lack	NOUN
biomedich-176	177	6	of	of	ADP
biomedich-176	177	7	a	a	DET
biomedich-176	177	8	mechanistic	mechanistic	ADJ
biomedich-176	177	9	approach	approach	NOUN
biomedich-176	177	10	to	to	ADP
biomedich-176	177	11	the	the	DET
biomedich-176	177	12	whole	whole	ADJ
biomedich-176	177	13	fish	fish	NOUN
biomedich-176	177	14	system	system	NOUN
biomedich-176	177	15	,	,	PUNCT
biomedich-176	177	16	and	and	CCONJ
biomedich-176	177	17	the	the	DET
biomedich-176	177	18	key	key	ADJ
biomedich-176	177	19	limiting	limiting	NOUN
biomedich-176	177	20	steps	step	NOUN
biomedich-176	177	21	for	for	ADP
biomedich-176	177	22	hybridization	hybridization	NOUN
biomedich-176	177	23	remain	remain	VERB
biomedich-176	177	24	uncertain	uncertain	ADJ
biomedich-176	177	25	(	(	PUNCT
biomedich-176	177	26	lima	lima	NOUN
biomedich-176	177	27	et	et	PROPN
biomedich-176	177	28	al	al	PROPN
biomedich-176	177	29	.	.	PROPN
biomedich-176	177	30	,	,	PUNCT
biomedich-176	177	31	2020	2020	NUM
biomedich-176	177	32	)	)	PUNCT
biomedich-176	177	33	.	.	PUNCT
biomedich-176	178	1	the	the	DET
biomedich-176	178	2	rate	rate	NOUN
biomedich-176	178	3	-	-	PUNCT
biomedich-176	178	4	limiting	limit	VERB
biomedich-176	178	5	phase	phase	NOUN
biomedich-176	178	6	was	be	AUX
biomedich-176	178	7	still	still	ADV
biomedich-176	178	8	the	the	DET
biomedich-176	178	9	slow	slow	ADJ
biomedich-176	178	10	reaction	reaction	NOUN
biomedich-176	178	11	rate	rate	NOUN
biomedich-176	178	12	of	of	ADP
biomedich-176	178	13	the	the	DET
biomedich-176	178	14	reagents	reagent	NOUN
biomedich-176	178	15	used	use	VERB
biomedich-176	178	16	in	in	ADP
biomedich-176	178	17	the	the	DET
biomedich-176	178	18	probe	probe	NOUN
biomedich-176	178	19	solution	solution	NOUN
biomedich-176	178	20	.	.	PUNCT
biomedich-176	179	1	in	in	ADP
biomedich-176	179	2	particular	particular	ADJ
biomedich-176	179	3	,	,	PUNCT
biomedich-176	179	4	hybridization	hybridization	NOUN
biomedich-176	179	5	was	be	AUX
biomedich-176	179	6	slowed	slow	VERB
biomedich-176	179	7	by	by	ADP
biomedich-176	179	8	using	use	VERB
biomedich-176	179	9	formamide	formamide	ADV
biomedich-176	179	10	,	,	PUNCT
biomedich-176	179	11	which	which	PRON
biomedich-176	179	12	acts	act	VERB
biomedich-176	179	13	as	as	ADP
biomedich-176	179	14	a	a	DET
biomedich-176	179	15	doublehelix	doublehelix	ADJ
biomedich-176	179	16	destabilizing	destabilizing	ADJ
biomedich-176	179	17	agent	agent	NOUN
biomedich-176	179	18	(	(	PUNCT
biomedich-176	179	19	nguyen	nguyen	NOUN
biomedich-176	179	20	et	et	PROPN
biomedich-176	179	21	al	al	PROPN
biomedich-176	179	22	.	.	PROPN
biomedich-176	179	23	,	,	PUNCT
biomedich-176	179	24	2018	2018	NUM
biomedich-176	179	25	)	)	PUNCT
biomedich-176	179	26	.	.	PUNCT
biomedich-176	180	1	however	however	ADV
biomedich-176	180	2	,	,	PUNCT
biomedich-176	180	3	a	a	DET
biomedich-176	180	4	fluorescence	fluorescence	NOUN
biomedich-176	180	5	microscope	microscope	NOUN
biomedich-176	180	6	is	be	AUX
biomedich-176	180	7	required	require	VERB
biomedich-176	180	8	for	for	ADP
biomedich-176	180	9	fish	fish	NOUN
biomedich-176	180	10	,	,	PUNCT
biomedich-176	180	11	and	and	CCONJ
biomedich-176	180	12	the	the	DET
biomedich-176	180	13	signals	signal	NOUN
biomedich-176	180	14	are	be	AUX
biomedich-176	180	15	labile	labile	ADJ
biomedich-176	180	16	and	and	CCONJ
biomedich-176	180	17	easily	easily	ADV
biomedich-176	180	18	fade	fade	VERB
biomedich-176	180	19	over	over	ADP
biomedich-176	180	20	time	time	NOUN
biomedich-176	180	21	(	(	PUNCT
biomedich-176	180	22	kim	kim	PROPN
biomedich-176	180	23	et	et	PROPN
biomedich-176	180	24	al	al	PROPN
biomedich-176	180	25	.	.	PROPN
biomedich-176	180	26	,	,	PUNCT
biomedich-176	180	27	2011	2011	NUM
biomedich-176	180	28	)	)	PUNCT
biomedich-176	180	29	.	.	PUNCT
biomedich-176	181	1	in	in	ADP
biomedich-176	181	2	recent	recent	ADJ
biomedich-176	181	3	years	year	NOUN
biomedich-176	181	4	,	,	PUNCT
biomedich-176	181	5	the	the	DET
biomedich-176	181	6	combination	combination	NOUN
biomedich-176	181	7	of	of	ADP
biomedich-176	181	8	microfluidic	microfluidic	ADJ
biomedich-176	181	9	techniques	technique	NOUN
biomedich-176	181	10	and	and	CCONJ
biomedich-176	181	11	fish	fish	NOUN
biomedich-176	181	12	have	have	AUX
biomedich-176	181	13	tackled	tackle	VERB
biomedich-176	181	14	weaknesses	weakness	NOUN
biomedich-176	181	15	in	in	ADP
biomedich-176	181	16	the	the	DET
biomedich-176	181	17	consumption	consumption	NOUN
biomedich-176	181	18	of	of	ADP
biomedich-176	181	19	probes	probe	NOUN
biomedich-176	181	20	and	and	CCONJ
biomedich-176	181	21	hybridization	hybridization	NOUN
biomedich-176	181	22	times	time	NOUN
biomedich-176	181	23	,	,	PUNCT
biomedich-176	181	24	making	make	VERB
biomedich-176	181	25	the	the	DET
biomedich-176	181	26	experimental	experimental	ADJ
biomedich-176	181	27	process	process	NOUN
biomedich-176	181	28	more	more	ADV
biomedich-176	181	29	sustainable	sustainable	ADJ
biomedich-176	181	30	and	and	CCONJ
biomedich-176	181	31	adaptable	adaptable	ADJ
biomedich-176	181	32	to	to	ADP
biomedich-176	181	33	high	high	ADJ
biomedich-176	181	34	-	-	PUNCT
biomedich-176	181	35	throughput	throughput	NOUN
biomedich-176	181	36	innovations	innovation	NOUN
biomedich-176	181	37	(	(	PUNCT
biomedich-176	181	38	huber	huber	PROPN
biomedich-176	181	39	et	et	PROPN
biomedich-176	181	40	al	al	PROPN
biomedich-176	181	41	.	.	PROPN
biomedich-176	181	42	,	,	PUNCT
biomedich-176	181	43	2018	2018	NUM
biomedich-176	181	44	)	)	PUNCT
biomedich-176	181	45	.	.	PUNCT
biomedich-176	182	1	as	as	SCONJ
biomedich-176	182	2	cytogenetic	cytogenetic	ADJ
biomedich-176	182	3	defects	defect	NOUN
biomedich-176	182	4	have	have	AUX
biomedich-176	182	5	been	be	AUX
biomedich-176	182	6	found	find	VERB
biomedich-176	182	7	in	in	ADP
biomedich-176	182	8	samples	sample	NOUN
biomedich-176	182	9	that	that	PRON
biomedich-176	182	10	appear	appear	VERB
biomedich-176	182	11	normal	normal	ADJ
biomedich-176	182	12	by	by	ADP
biomedich-176	182	13	morphological	morphological	ADJ
biomedich-176	182	14	and	and	CCONJ
biomedich-176	182	15	conventional	conventional	ADJ
biomedich-176	182	16	cytogenetic	cytogenetic	ADJ
biomedich-176	182	17	examination	examination	NOUN
biomedich-176	182	18	,	,	PUNCT
biomedich-176	182	19	the	the	DET
biomedich-176	182	20	fish	fish	NOUN
biomedich-176	182	21	analysis	analysis	NOUN
biomedich-176	182	22	provides	provide	VERB
biomedich-176	182	23	enhanced	enhanced	ADJ
biomedich-176	182	24	sensitivity	sensitivity	NOUN
biomedich-176	182	25	in	in	ADP
biomedich-176	182	26	many	many	ADJ
biomedich-176	182	27	cases	case	NOUN
biomedich-176	182	28	.	.	PUNCT
biomedich-176	183	1	the	the	DET
biomedich-176	183	2	combination	combination	NOUN
biomedich-176	183	3	of	of	ADP
biomedich-176	183	4	cytogenetic	cytogenetic	ADJ
biomedich-176	183	5	,	,	PUNCT
biomedich-176	183	6	fish	fish	NOUN
biomedich-176	183	7	and	and	CCONJ
biomedich-176	183	8	molecular	molecular	ADJ
biomedich-176	183	9	studies	study	NOUN
biomedich-176	183	10	offers	offer	VERB
biomedich-176	183	11	a	a	DET
biomedich-176	183	12	powerful	powerful	ADJ
biomedich-176	183	13	method	method	NOUN
biomedich-176	183	14	for	for	ADP
biomedich-176	183	15	diagnosing	diagnosing	NOUN
biomedich-176	183	16	and	and	CCONJ
biomedich-176	183	17	sub	sub	NOUN
biomedich-176	183	18	classifying	classify	VERB
biomedich-176	183	19	malignant	malignant	ADJ
biomedich-176	183	20	diseases	disease	NOUN
biomedich-176	183	21	into	into	ADP
biomedich-176	183	22	clinically	clinically	ADV
biomedich-176	183	23	and	and	CCONJ
biomedich-176	183	24	biologically	biologically	ADV
biomedich-176	183	25	important	important	ADJ
biomedich-176	183	26	subgroups	subgroup	NOUN
biomedich-176	183	27	,	,	PUNCT
biomedich-176	183	28	selecting	select	VERB
biomedich-176	183	29	effective	effective	ADJ
biomedich-176	183	30	therapies	therapy	NOUN
biomedich-176	183	31	,	,	PUNCT
biomedich-176	183	32	and	and	CCONJ
biomedich-176	183	33	monitoring	monitor	VERB
biomedich-176	183	34	the	the	DET
biomedich-176	183	35	effectiveness	effectiveness	NOUN
biomedich-176	183	36	of	of	ADP
biomedich-176	183	37	therapeutic	therapeutic	ADJ
biomedich-176	183	38	regimens	regimen	NOUN
biomedich-176	183	39	(	(	PUNCT
biomedich-176	183	40	gozzetti	gozzetti	NOUN
biomedich-176	183	41	and	and	CCONJ
biomedich-176	183	42	le	le	X
biomedich-176	183	43	,	,	PUNCT
biomedich-176	183	44	2000	2000	NUM
biomedich-176	183	45	)	)	PUNCT
biomedich-176	183	46	.	.	PUNCT
biomedich-176	184	1	it	it	PRON
biomedich-176	184	2	is	be	AUX
biomedich-176	184	3	also	also	ADV
biomedich-176	184	4	recommended	recommend	VERB
biomedich-176	184	5	that	that	SCONJ
biomedich-176	184	6	fish	fish	NOUN
biomedich-176	184	7	and	and	CCONJ
biomedich-176	184	8	cgh	cgh	PROPN
biomedich-176	184	9	findings	finding	NOUN
biomedich-176	184	10	be	be	AUX
biomedich-176	184	11	re	re	VERB
biomedich-176	184	12	-	-	VERB
biomedich-176	184	13	evaluated	evaluate	VERB
biomedich-176	184	14	by	by	ADP
biomedich-176	184	15	one	one	NUM
biomedich-176	184	16	another	another	DET
biomedich-176	184	17	52	52	NUM
biomedich-176	184	18	biology	biology	NOUN
biomedich-176	184	19	,	,	PUNCT
biomedich-176	184	20	medicine	medicine	NOUN
biomedich-176	184	21	,	,	PUNCT
biomedich-176	184	22	&	&	CCONJ
biomedich-176	184	23	natural	natural	ADJ
biomedich-176	184	24	product	product	NOUN
biomedich-176	184	25	chemistry	chemistry	NOUN
biomedich-176	184	26	11	11	NUM
biomedich-176	184	27	(	(	PUNCT
biomedich-176	184	28	1	1	NUM
biomedich-176	184	29	)	)	PUNCT
biomedich-176	184	30	,	,	PUNCT
biomedich-176	184	31	2022	2022	NUM
biomedich-176	184	32	:	:	PUNCT
biomedich-176	184	33	45	45	NUM
biomedich-176	184	34	-	-	SYM
biomedich-176	184	35	54	54	NUM
biomedich-176	184	36	to	to	PART
biomedich-176	184	37	resolve	resolve	VERB
biomedich-176	184	38	these	these	DET
biomedich-176	184	39	technological	technological	ADJ
biomedich-176	184	40	artefacts	artefact	NOUN
biomedich-176	184	41	.	.	PUNCT
biomedich-176	185	1	however	however	ADV
biomedich-176	185	2	,	,	PUNCT
biomedich-176	185	3	cgh	cgh	PROPN
biomedich-176	185	4	is	be	AUX
biomedich-176	185	5	of	of	ADP
biomedich-176	185	6	potential	potential	ADJ
biomedich-176	185	7	benefit	benefit	NOUN
biomedich-176	185	8	in	in	ADP
biomedich-176	185	9	characterizing	characterize	VERB
biomedich-176	185	10	chromosomal	chromosomal	ADJ
biomedich-176	185	11	alterations	alteration	NOUN
biomedich-176	185	12	and	and	CCONJ
biomedich-176	185	13	could	could	AUX
biomedich-176	185	14	help	help	VERB
biomedich-176	185	15	produce	produce	VERB
biomedich-176	185	16	tumour	tumour	NOUN
biomedich-176	185	17	-	-	PUNCT
biomedich-176	185	18	specific	specific	ADJ
biomedich-176	185	19	sets	set	NOUN
biomedich-176	185	20	of	of	ADP
biomedich-176	185	21	fish	fish	NOUN
biomedich-176	185	22	probes	probe	NOUN
biomedich-176	185	23	within	within	ADP
biomedich-176	185	24	a	a	DET
biomedich-176	185	25	few	few	ADJ
biomedich-176	185	26	days	day	NOUN
biomedich-176	185	27	to	to	PART
biomedich-176	185	28	obtain	obtain	VERB
biomedich-176	185	29	genetic	genetic	ADJ
biomedich-176	185	30	information	information	NOUN
biomedich-176	185	31	of	of	ADP
biomedich-176	185	32	prognostic	prognostic	ADJ
biomedich-176	185	33	value	value	NOUN
biomedich-176	185	34	(	(	PUNCT
biomedich-176	185	35	jacobsen	jacobsen	PROPN
biomedich-176	185	36	et	et	PROPN
biomedich-176	185	37	al	al	PROPN
biomedich-176	185	38	.	.	PROPN
biomedich-176	185	39	,	,	PUNCT
biomedich-176	185	40	2000	2000	NUM
biomedich-176	185	41	)	)	PUNCT
biomedich-176	185	42	.	.	PUNCT
biomedich-176	186	1	conclusions	conclusion	NOUN
biomedich-176	186	2	from	from	ADP
biomedich-176	186	3	this	this	DET
biomedich-176	186	4	review	review	NOUN
biomedich-176	186	5	article	article	NOUN
biomedich-176	186	6	conducted	conduct	VERB
biomedich-176	186	7	the	the	DET
biomedich-176	186	8	following	follow	VERB
biomedich-176	186	9	points	point	NOUN
biomedich-176	186	10	as	as	SCONJ
biomedich-176	186	11	follows	follow	VERB
biomedich-176	186	12	:	:	PUNCT
biomedich-176	186	13	1	1	X
biomedich-176	186	14	.	.	X
biomedich-176	186	15	fluorescence	fluorescence	NOUN
biomedich-176	186	16	in	in	ADP
biomedich-176	186	17	situ	situ	ADJ
biomedich-176	186	18	hybridization	hybridization	NOUN
biomedich-176	186	19	(	(	PUNCT
biomedich-176	186	20	fish	fish	NOUN
biomedich-176	186	21	)	)	PUNCT
biomedich-176	186	22	more	more	ADV
biomedich-176	186	23	accurate	accurate	ADJ
biomedich-176	186	24	than	than	ADP
biomedich-176	186	25	classical	classical	ADJ
biomedich-176	186	26	cytogenetic	cytogenetic	NOUN
biomedich-176	186	27	such	such	ADJ
biomedich-176	186	28	as	as	ADP
biomedich-176	186	29	karyotyping	karyotype	VERB
biomedich-176	186	30	2	2	NUM
biomedich-176	186	31	.	.	PUNCT
biomedich-176	186	32	comparative	comparative	ADJ
biomedich-176	186	33	genomic	genomic	NOUN
biomedich-176	186	34	hybridization	hybridization	NOUN
biomedich-176	186	35	(	(	PUNCT
biomedich-176	186	36	cgh	cgh	PROPN
biomedich-176	186	37	)	)	PUNCT
biomedich-176	186	38	is	be	AUX
biomedich-176	186	39	very	very	ADV
biomedich-176	186	40	important	important	ADJ
biomedich-176	186	41	for	for	ADP
biomedich-176	186	42	the	the	DET
biomedich-176	186	43	create	create	NOUN
biomedich-176	186	44	a	a	DET
biomedich-176	186	45	wide	wide	ADJ
biomedich-176	186	46	range	range	NOUN
biomedich-176	186	47	of	of	ADP
biomedich-176	186	48	chromosomal	chromosomal	ADJ
biomedich-176	186	49	profile	profile	NOUN
biomedich-176	186	50	3	3	X
biomedich-176	186	51	.	.	PUNCT
biomedich-176	187	1	both	both	DET
biomedich-176	187	2	fluorescence	fluorescence	NOUN
biomedich-176	187	3	in	in	ADP
biomedich-176	187	4	situ	situ	ADJ
biomedich-176	187	5	hybridization	hybridization	NOUN
biomedich-176	187	6	(	(	PUNCT
biomedich-176	187	7	fish	fish	NOUN
biomedich-176	187	8	)	)	PUNCT
biomedich-176	187	9	and	and	CCONJ
biomedich-176	187	10	comparative	comparative	ADJ
biomedich-176	187	11	genomic	genomic	NOUN
biomedich-176	187	12	hybridization	hybridization	NOUN
biomedich-176	187	13	(	(	PUNCT
biomedich-176	187	14	cgh	cgh	PROPN
biomedich-176	187	15	)	)	PUNCT
biomedich-176	187	16	have	have	VERB
biomedich-176	187	17	many	many	ADJ
biomedich-176	187	18	limitations	limitation	NOUN
biomedich-176	187	19	and	and	CCONJ
biomedich-176	187	20	disadvantages	disadvantage	NOUN
biomedich-176	187	21	4	4	NUM
biomedich-176	188	1	.	.	PUNCT
biomedich-176	188	2	probes	probe	NOUN
biomedich-176	188	3	is	be	AUX
biomedich-176	188	4	the	the	DET
biomedich-176	188	5	key	key	ADJ
biomedich-176	188	6	success	success	NOUN
biomedich-176	188	7	for	for	ADP
biomedich-176	188	8	both	both	DET
biomedich-176	188	9	fluorescence	fluorescence	NOUN
biomedich-176	188	10	in	in	ADP
biomedich-176	188	11	situ	situ	ADJ
biomedich-176	188	12	hybridization	hybridization	NOUN
biomedich-176	188	13	(	(	PUNCT
biomedich-176	188	14	fish	fish	NOUN
biomedich-176	188	15	)	)	PUNCT
biomedich-176	188	16	and	and	CCONJ
biomedich-176	188	17	comparative	comparative	ADJ
biomedich-176	188	18	genomic	genomic	NOUN
biomedich-176	188	19	hybridization	hybridization	NOUN
biomedich-176	188	20	(	(	PUNCT
biomedich-176	188	21	cgh	cgh	PROPN
biomedich-176	188	22	)	)	PUNCT
biomedich-176	188	23	conflict	conflict	NOUN
biomedich-176	188	24	of	of	ADP
biomedich-176	188	25	interest	interest	NOUN
biomedich-176	188	26	:	:	PUNCT
biomedich-176	188	27	the	the	DET
biomedich-176	188	28	author	author	NOUN
biomedich-176	188	29	declares	declare	VERB
biomedich-176	188	30	no	no	DET
biomedich-176	188	31	conflicts	conflict	NOUN
biomedich-176	188	32	of	of	ADP
biomedich-176	188	33	interest	interest	NOUN
biomedich-176	188	34	.	.	PUNCT
biomedich-176	189	1	references	reference	NOUN
biomedich-176	189	2	alayed	alaye	VERB
biomedich-176	189	3	,	,	PUNCT
biomedich-176	189	4	k.	k.	PROPN
biomedich-176	189	5	,	,	PUNCT
biomedich-176	189	6	medeiros	medeiros	PROPN
biomedich-176	189	7	,	,	PUNCT
biomedich-176	189	8	l.	l.	PROPN
biomedich-176	189	9	j.	j.	PROPN
biomedich-176	189	10	,	,	PUNCT
biomedich-176	189	11	schultz	schultz	PROPN
biomedich-176	189	12	,	,	PUNCT
biomedich-176	189	13	r.	r.	PROPN
biomedich-176	189	14	a.	a.	PROPN
biomedich-176	189	15	,	,	PUNCT
biomedich-176	189	16	cortes	corte	NOUN
biomedich-176	189	17	,	,	PUNCT
biomedich-176	189	18	j.	j.	PROPN
biomedich-176	189	19	,	,	PUNCT
biomedich-176	189	20	lu	lu	PROPN
biomedich-176	189	21	,	,	PUNCT
biomedich-176	189	22	g.	g.	PROPN
biomedich-176	189	23	,	,	PUNCT
biomedich-176	189	24	bueso	bueso	NOUN
biomedich-176	189	25	-	-	PUNCT
biomedich-176	189	26	ramos	ramos	PROPN
biomedich-176	189	27	,	,	PUNCT
biomedich-176	189	28	c.	c.	PROPN
biomedich-176	189	29	e.	e.	PROPN
biomedich-176	189	30	,	,	PUNCT
biomedich-176	189	31	&	&	CCONJ
biomedich-176	189	32	konoplev	konoplev	PROPN
biomedich-176	189	33	,	,	PUNCT
biomedich-176	189	34	s.	s.	PROPN
biomedich-176	189	35	(	(	PUNCT
biomedich-176	189	36	2013	2013	NUM
biomedich-176	189	37	)	)	PUNCT
biomedich-176	189	38	.	.	PUNCT
biomedich-176	190	1	value	value	NOUN
biomedich-176	190	2	of	of	ADP
biomedich-176	190	3	oligonucleotide	oligonucleotide	NOUN
biomedich-176	190	4	-	-	PUNCT
biomedich-176	190	5	based	base	VERB
biomedich-176	190	6	array	array	NOUN
biomedich-176	190	7	comparative	comparative	ADJ
biomedich-176	190	8	genomic	genomic	NOUN
biomedich-176	190	9	hybridization	hybridization	NOUN
biomedich-176	190	10	for	for	ADP
biomedich-176	190	11	diagnosis	diagnosis	NOUN
biomedich-176	190	12	of	of	ADP
biomedich-176	190	13	acute	acute	ADJ
biomedich-176	190	14	promyelocytic	promyelocytic	ADJ
biomedich-176	190	15	leukemia	leukemia	NOUN
biomedich-176	190	16	in	in	ADP
biomedich-176	190	17	a	a	DET
biomedich-176	190	18	patient	patient	NOUN
biomedich-176	190	19	negative	negative	NOUN
biomedich-176	190	20	for	for	ADP
biomedich-176	190	21	t	t	PROPN
biomedich-176	190	22	(	(	PUNCT
biomedich-176	190	23	15	15	NUM
biomedich-176	190	24	;	;	PUNCT
biomedich-176	190	25	17	17	NUM
biomedich-176	190	26	)	)	PUNCT
biomedich-176	190	27	(	(	PUNCT
biomedich-176	190	28	q24	q24	NOUN
biomedich-176	190	29	.	.	PROPN
biomedich-176	191	1	1	1	NUM
biomedich-176	191	2	;	;	PUNCT
biomedich-176	191	3	q21	q21	ADJ
biomedich-176	191	4	.	.	PUNCT
biomedich-176	192	1	2)/promyelocytic	2)/promyelocytic	ADJ
biomedich-176	192	2	leukemia	leukemia	NOUN
biomedich-176	192	3	-	-	PUNCT
biomedich-176	192	4	retinoic	retinoic	NOUN
biomedich-176	192	5	acid	acid	NOUN
biomedich-176	192	6	receptor	receptor	NOUN
biomedich-176	192	7	,	,	PUNCT
biomedich-176	192	8	alpha	alpha	NOUN
biomedich-176	192	9	by	by	ADP
biomedich-176	192	10	conventional	conventional	ADJ
biomedich-176	192	11	cytogenetics	cytogenetic	NOUN
biomedich-176	192	12	and	and	CCONJ
biomedich-176	192	13	fluorescence	fluorescence	NOUN
biomedich-176	192	14	in	in	ADP
biomedich-176	192	15	situ	situ	ADJ
biomedich-176	192	16	hybridization	hybridization	NOUN
biomedich-176	192	17	.	.	PUNCT
biomedich-176	193	1	clinical	clinical	ADJ
biomedich-176	193	2	lymphoma	lymphoma	NOUN
biomedich-176	193	3	,	,	PUNCT
biomedich-176	193	4	myeloma	myeloma	NOUN
biomedich-176	193	5	and	and	CCONJ
biomedich-176	193	6	leukemia	leukemia	NOUN
biomedich-176	193	7	,	,	PUNCT
biomedich-176	193	8	13(4	13(4	NUM
biomedich-176	193	9	)	)	PUNCT
biomedich-176	193	10	,	,	PUNCT
biomedich-176	193	11	507	507	NUM
biomedich-176	193	12	-	-	SYM
biomedich-176	193	13	510	510	NUM
biomedich-176	193	14	.	.	PUNCT
biomedich-176	193	15	albertson	albertson	PROPN
biomedich-176	193	16	,	,	PUNCT
biomedich-176	193	17	d.	d.	PROPN
biomedich-176	193	18	g.	g.	PROPN
biomedich-176	193	19	(	(	PUNCT
biomedich-176	193	20	2003	2003	NUM
biomedich-176	193	21	)	)	PUNCT
biomedich-176	193	22	.	.	PUNCT
biomedich-176	194	1	profiling	profile	VERB
biomedich-176	194	2	breast	breast	NOUN
biomedich-176	194	3	cancer	cancer	NOUN
biomedich-176	194	4	by	by	ADP
biomedich-176	194	5	array	array	NOUN
biomedich-176	194	6	cgh	cgh	PROPN
biomedich-176	194	7	.	.	PUNCT
biomedich-176	194	8	breast	breast	NOUN
biomedich-176	194	9	cancer	cancer	NOUN
biomedich-176	194	10	research	research	NOUN
biomedich-176	194	11	and	and	CCONJ
biomedich-176	194	12	treatment	treatment	NOUN
biomedich-176	194	13	,	,	PUNCT
biomedich-176	194	14	78(3	78(3	NOUN
biomedich-176	194	15	)	)	PUNCT
biomedich-176	194	16	,	,	PUNCT
biomedich-176	194	17	289	289	NUM
biomedich-176	194	18	-	-	SYM
biomedich-176	194	19	298	298	NUM
biomedich-176	194	20	.	.	PUNCT
biomedich-176	195	1	bar‐am	bar‐am	PROPN
biomedich-176	195	2	,	,	PUNCT
biomedich-176	195	3	i.	i.	PROPN
biomedich-176	195	4	,	,	PUNCT
biomedich-176	195	5	mor	mor	PROPN
biomedich-176	195	6	,	,	PUNCT
biomedich-176	195	7	o.	o.	PROPN
biomedich-176	195	8	,	,	PUNCT
biomedich-176	195	9	shiloh	shiloh	PROPN
biomedich-176	195	10	,	,	PUNCT
biomedich-176	195	11	y.	y.	PROPN
biomedich-176	195	12	,	,	PUNCT
biomedich-176	195	13	avivi	avivi	PROPN
biomedich-176	195	14	,	,	PUNCT
biomedich-176	195	15	l.	l.	PROPN
biomedich-176	195	16	,	,	PUNCT
biomedich-176	195	17	&	&	CCONJ
biomedich-176	195	18	yeger	yeger	NOUN
biomedich-176	195	19	,	,	PUNCT
biomedich-176	195	20	h.	h.	PROPN
biomedich-176	195	21	(	(	PUNCT
biomedich-176	195	22	1992	1992	NUM
biomedich-176	195	23	)	)	PUNCT
biomedich-176	195	24	.	.	PUNCT
biomedich-176	196	1	detection	detection	NOUN
biomedich-176	196	2	of	of	ADP
biomedich-176	196	3	amplified	amplify	VERB
biomedich-176	196	4	dna	dna	PROPN
biomedich-176	196	5	sequences	sequence	NOUN
biomedich-176	196	6	in	in	ADP
biomedich-176	196	7	human	human	ADJ
biomedich-176	196	8	tumor	tumor	NOUN
biomedich-176	196	9	cell	cell	NOUN
biomedich-176	196	10	lines	line	NOUN
biomedich-176	196	11	by	by	ADP
biomedich-176	196	12	fluorescence	fluorescence	NOUN
biomedich-176	196	13	in	in	ADP
biomedich-176	196	14	situ	situ	ADJ
biomedich-176	196	15	hybridization	hybridization	NOUN
biomedich-176	196	16	.	.	PUNCT
biomedich-176	197	1	genes	gene	NOUN
biomedich-176	197	2	,	,	PUNCT
biomedich-176	197	3	chromosomes	chromosome	NOUN
biomedich-176	197	4	and	and	CCONJ
biomedich-176	197	5	cancer	cancer	NOUN
biomedich-176	197	6	,	,	PUNCT
biomedich-176	197	7	4(4	4(4	NUM
biomedich-176	197	8	)	)	PUNCT
biomedich-176	197	9	,	,	PUNCT
biomedich-176	197	10	314	314	NUM
biomedich-176	197	11	-	-	SYM
biomedich-176	197	12	320	320	NUM
biomedich-176	197	13	.	.	PUNCT
biomedich-176	198	1	bartlett	bartlett	PROPN
biomedich-176	198	2	,	,	PUNCT
biomedich-176	198	3	j.	j.	PROPN
biomedich-176	198	4	m.	m.	PROPN
biomedich-176	198	5	(	(	PUNCT
biomedich-176	198	6	2004	2004	NUM
biomedich-176	198	7	)	)	PUNCT
biomedich-176	198	8	.	.	PUNCT
biomedich-176	199	1	fluorescence	fluorescence	NOUN
biomedich-176	199	2	in	in	ADP
biomedich-176	199	3	situ	situ	ADJ
biomedich-176	199	4	hybridization	hybridization	NOUN
biomedich-176	199	5	,	,	PUNCT
biomedich-176	199	6	in	in	ADP
biomedich-176	199	7	molecular	molecular	ADJ
biomedich-176	199	8	diagnosis	diagnosis	NOUN
biomedich-176	199	9	of	of	ADP
biomedich-176	199	10	cancer	cancer	NOUN
biomedich-176	199	11	.	.	PUNCT
biomedich-176	200	1	bièche	bièche	PROPN
biomedich-176	200	2	,	,	PUNCT
biomedich-176	200	3	i.	i.	PROPN
biomedich-176	200	4	,	,	PUNCT
biomedich-176	200	5	&	&	CCONJ
biomedich-176	200	6	lidereau	lidereau	PROPN
biomedich-176	200	7	,	,	PUNCT
biomedich-176	200	8	r.	r.	PROPN
biomedich-176	200	9	(	(	PUNCT
biomedich-176	200	10	1995	1995	NUM
biomedich-176	200	11	)	)	PUNCT
biomedich-176	200	12	.	.	PUNCT
biomedich-176	201	1	genetic	genetic	ADJ
biomedich-176	201	2	alterations	alteration	NOUN
biomedich-176	201	3	in	in	ADP
biomedich-176	201	4	breast	breast	NOUN
biomedich-176	201	5	cancer	cancer	NOUN
biomedich-176	201	6	.	.	PUNCT
biomedich-176	202	1	genes	gene	NOUN
biomedich-176	202	2	,	,	PUNCT
biomedich-176	202	3	chromosomes	chromosome	NOUN
biomedich-176	202	4	and	and	CCONJ
biomedich-176	202	5	cancer	cancer	NOUN
biomedich-176	202	6	,	,	PUNCT
biomedich-176	202	7	14(4	14(4	NUM
biomedich-176	202	8	)	)	PUNCT
biomedich-176	202	9	,	,	PUNCT
biomedich-176	202	10	227	227	NUM
biomedich-176	202	11	-	-	SYM
biomedich-176	202	12	251	251	NUM
biomedich-176	202	13	.	.	PUNCT
biomedich-176	203	1	bièche	bièche	PROPN
biomedich-176	203	2	,	,	PUNCT
biomedich-176	203	3	i.	i.	PROPN
biomedich-176	203	4	,	,	PUNCT
biomedich-176	203	5	champème	champème	PROPN
biomedich-176	203	6	,	,	PUNCT
biomedich-176	203	7	m.	m.	PROPN
biomedich-176	203	8	h.	h.	PROPN
biomedich-176	203	9	,	,	PUNCT
biomedich-176	203	10	&	&	CCONJ
biomedich-176	203	11	lidereau	lidereau	PROPN
biomedich-176	203	12	,	,	PUNCT
biomedich-176	203	13	r.	r.	PROPN
biomedich-176	203	14	(	(	PUNCT
biomedich-176	203	15	1995	1995	NUM
biomedich-176	203	16	)	)	PUNCT
biomedich-176	203	17	.	.	PUNCT
biomedich-176	204	1	loss	loss	NOUN
biomedich-176	204	2	and	and	CCONJ
biomedich-176	204	3	gain	gain	NOUN
biomedich-176	204	4	of	of	ADP
biomedich-176	204	5	distinct	distinct	ADJ
biomedich-176	204	6	regions	region	NOUN
biomedich-176	204	7	of	of	ADP
biomedich-176	204	8	chromosome	chromosome	NOUN
biomedich-176	204	9	1q	1q	NUM
biomedich-176	204	10	in	in	ADP
biomedich-176	204	11	primary	primary	ADJ
biomedich-176	204	12	breast	breast	NOUN
biomedich-176	204	13	cancer	cancer	NOUN
biomedich-176	204	14	.	.	PUNCT
biomedich-176	205	1	clinical	clinical	ADJ
biomedich-176	205	2	cancer	cancer	NOUN
biomedich-176	205	3	research	research	NOUN
biomedich-176	205	4	,	,	PUNCT
biomedich-176	205	5	1(1	1(1	NUM
biomedich-176	205	6	)	)	PUNCT
biomedich-176	205	7	,	,	PUNCT
biomedich-176	205	8	123	123	NUM
biomedich-176	205	9	-	-	SYM
biomedich-176	205	10	127	127	NUM
biomedich-176	205	11	.	.	PUNCT
biomedich-176	206	1	bishop	bishop	PROPN
biomedich-176	206	2	,	,	PUNCT
biomedich-176	206	3	r.	r.	PROPN
biomedich-176	206	4	(	(	PUNCT
biomedich-176	206	5	2010	2010	NUM
biomedich-176	206	6	)	)	PUNCT
biomedich-176	206	7	.	.	PUNCT
biomedich-176	207	1	applications	application	NOUN
biomedich-176	207	2	of	of	ADP
biomedich-176	207	3	fluorescence	fluorescence	NOUN
biomedich-176	207	4	in	in	ADP
biomedich-176	207	5	situ	situ	ADJ
biomedich-176	207	6	hybridization	hybridization	NOUN
biomedich-176	207	7	(	(	PUNCT
biomedich-176	207	8	fish	fish	NOUN
biomedich-176	207	9	)	)	PUNCT
biomedich-176	207	10	in	in	ADP
biomedich-176	207	11	detecting	detect	VERB
biomedich-176	207	12	genetic	genetic	ADJ
biomedich-176	207	13	aberrations	aberration	NOUN
biomedich-176	207	14	of	of	ADP
biomedich-176	207	15	medical	medical	ADJ
biomedich-176	207	16	significance	significance	NOUN
biomedich-176	207	17	.	.	PUNCT
biomedich-176	208	1	bioscience	bioscience	NOUN
biomedich-176	208	2	horizons	horizon	NOUN
biomedich-176	208	3	,	,	PUNCT
biomedich-176	208	4	3(1	3(1	NUM
biomedich-176	208	5	)	)	PUNCT
biomedich-176	208	6	,	,	PUNCT
biomedich-176	208	7	85	85	NUM
biomedich-176	208	8	-	-	SYM
biomedich-176	208	9	95	95	NUM
biomedich-176	208	10	.	.	PUNCT
biomedich-176	209	1	bolland	bolland	PROPN
biomedich-176	209	2	,	,	PUNCT
biomedich-176	209	3	d.	d.	PROPN
biomedich-176	209	4	j.	j.	PROPN
biomedich-176	209	5	,	,	PUNCT
biomedich-176	209	6	king	king	PROPN
biomedich-176	209	7	,	,	PUNCT
biomedich-176	209	8	m.	m.	PROPN
biomedich-176	209	9	r.	r.	PROPN
biomedich-176	209	10	,	,	PUNCT
biomedich-176	209	11	reik	reik	PROPN
biomedich-176	209	12	,	,	PUNCT
biomedich-176	209	13	w.	w.	PROPN
biomedich-176	209	14	,	,	PUNCT
biomedich-176	209	15	corcoran	corcoran	NOUN
biomedich-176	209	16	,	,	PUNCT
biomedich-176	209	17	a.	a.	PROPN
biomedich-176	209	18	e.	e.	PROPN
biomedich-176	209	19	,	,	PUNCT
biomedich-176	209	20	&	&	CCONJ
biomedich-176	209	21	krueger	krueger	PROPN
biomedich-176	209	22	,	,	PUNCT
biomedich-176	209	23	c.	c.	PROPN
biomedich-176	209	24	(	(	PUNCT
biomedich-176	209	25	2013	2013	NUM
biomedich-176	209	26	)	)	PUNCT
biomedich-176	209	27	.	.	PUNCT
biomedich-176	210	1	robust	robust	ADJ
biomedich-176	210	2	3d	3d	NUM
biomedich-176	210	3	dna	dna	NOUN
biomedich-176	210	4	fish	fish	NOUN
biomedich-176	210	5	using	use	VERB
biomedich-176	210	6	directly	directly	ADV
biomedich-176	210	7	labeled	label	VERB
biomedich-176	210	8	probes	probe	NOUN
biomedich-176	210	9	.	.	PUNCT
biomedich-176	211	1	jove	jove	PROPN
biomedich-176	211	2	(	(	PUNCT
biomedich-176	211	3	journal	journal	NOUN
biomedich-176	211	4	of	of	ADP
biomedich-176	211	5	visualized	visualized	ADJ
biomedich-176	211	6	experiments	experiment	NOUN
biomedich-176	211	7	)	)	PUNCT
biomedich-176	211	8	,	,	PUNCT
biomedich-176	211	9	(	(	PUNCT
biomedich-176	211	10	78	78	NUM
biomedich-176	211	11	)	)	PUNCT
biomedich-176	211	12	,	,	PUNCT
biomedich-176	211	13	e50587	e50587	PROPN
biomedich-176	211	14	.	.	PUNCT
biomedich-176	211	15	bridge	bridge	PROPN
biomedich-176	211	16	,	,	PUNCT
biomedich-176	211	17	j.	j.	PROPN
biomedich-176	211	18	a.	a.	PROPN
biomedich-176	211	19	(	(	PUNCT
biomedich-176	211	20	2008	2008	NUM
biomedich-176	211	21	)	)	PUNCT
biomedich-176	211	22	.	.	PUNCT
biomedich-176	212	1	advantages	advantage	NOUN
biomedich-176	212	2	and	and	CCONJ
biomedich-176	212	3	limitations	limitation	NOUN
biomedich-176	212	4	of	of	ADP
biomedich-176	212	5	cytogenetic	cytogenetic	ADJ
biomedich-176	212	6	,	,	PUNCT
biomedich-176	212	7	molecular	molecular	ADJ
biomedich-176	212	8	cytogenetic	cytogenetic	ADJ
biomedich-176	212	9	,	,	PUNCT
biomedich-176	212	10	and	and	CCONJ
biomedich-176	212	11	molecular	molecular	ADJ
biomedich-176	212	12	diagnostic	diagnostic	ADJ
biomedich-176	212	13	testing	testing	NOUN
biomedich-176	212	14	in	in	ADP
biomedich-176	212	15	mesenchymal	mesenchymal	ADJ
biomedich-176	212	16	neoplasms	neoplasm	NOUN
biomedich-176	212	17	.	.	PUNCT
biomedich-176	213	1	journal	journal	PROPN
biomedich-176	213	2	of	of	ADP
biomedich-176	213	3	orthopaedic	orthopaedic	ADJ
biomedich-176	213	4	science	science	NOUN
biomedich-176	213	5	,	,	PUNCT
biomedich-176	213	6	13(3	13(3	NUM
biomedich-176	213	7	)	)	PUNCT
biomedich-176	213	8	,	,	PUNCT
biomedich-176	213	9	273	273	NUM
biomedich-176	213	10	.	.	PUNCT
biomedich-176	213	11	brown	brown	PROPN
biomedich-176	213	12	,	,	PUNCT
biomedich-176	213	13	l.	l.	PROPN
biomedich-176	213	14	a.	a.	PROPN
biomedich-176	213	15	,	,	PUNCT
biomedich-176	213	16	&	&	CCONJ
biomedich-176	213	17	huntsman	huntsman	PROPN
biomedich-176	213	18	,	,	PUNCT
biomedich-176	213	19	d.	d.	PROPN
biomedich-176	213	20	(	(	PUNCT
biomedich-176	213	21	2007	2007	NUM
biomedich-176	213	22	)	)	PUNCT
biomedich-176	213	23	.	.	PUNCT
biomedich-176	214	1	fluorescent	fluorescent	NOUN
biomedich-176	214	2	in	in	ADP
biomedich-176	214	3	situ	situ	ADJ
biomedich-176	214	4	hybridization	hybridization	NOUN
biomedich-176	214	5	on	on	ADP
biomedich-176	214	6	tissue	tissue	NOUN
biomedich-176	214	7	microarrays	microarray	NOUN
biomedich-176	214	8	:	:	PUNCT
biomedich-176	214	9	challenges	challenge	NOUN
biomedich-176	214	10	and	and	CCONJ
biomedich-176	214	11	solutions	solution	NOUN
biomedich-176	214	12	.	.	PUNCT
biomedich-176	215	1	journal	journal	NOUN
biomedich-176	215	2	of	of	ADP
biomedich-176	215	3	molecular	molecular	ADJ
biomedich-176	215	4	histology	histology	NOUN
biomedich-176	215	5	,	,	PUNCT
biomedich-176	215	6	38(2	38(2	NOUN
biomedich-176	215	7	)	)	PUNCT
biomedich-176	215	8	,	,	PUNCT
biomedich-176	215	9	151	151	NUM
biomedich-176	215	10	-	-	SYM
biomedich-176	215	11	157	157	NUM
biomedich-176	215	12	.	.	PUNCT
biomedich-176	216	1	chrzanowska	chrzanowska	PROPN
biomedich-176	216	2	,	,	PUNCT
biomedich-176	216	3	n.	n.	NOUN
biomedich-176	216	4	m.	m.	NOUN
biomedich-176	216	5	,	,	PUNCT
biomedich-176	216	6	kowalewski	kowalewski	PROPN
biomedich-176	216	7	,	,	PUNCT
biomedich-176	216	8	j.	j.	PROPN
biomedich-176	216	9	,	,	PUNCT
biomedich-176	216	10	&	&	CCONJ
biomedich-176	216	11	lewandowska	lewandowska	PROPN
biomedich-176	216	12	,	,	PUNCT
biomedich-176	216	13	m.	m.	NOUN
biomedich-176	216	14	a.	a.	NOUN
biomedich-176	216	15	(	(	PUNCT
biomedich-176	216	16	2020	2020	NUM
biomedich-176	216	17	)	)	PUNCT
biomedich-176	216	18	.	.	PUNCT
biomedich-176	217	1	use	use	NOUN
biomedich-176	217	2	of	of	ADP
biomedich-176	217	3	fluorescence	fluorescence	NOUN
biomedich-176	217	4	in	in	ADP
biomedich-176	217	5	situ	situ	ADJ
biomedich-176	217	6	hybridization	hybridization	NOUN
biomedich-176	217	7	(	(	PUNCT
biomedich-176	217	8	fish	fish	NOUN
biomedich-176	217	9	)	)	PUNCT
biomedich-176	217	10	in	in	ADP
biomedich-176	217	11	diagnosis	diagnosis	NOUN
biomedich-176	217	12	and	and	CCONJ
biomedich-176	217	13	tailored	tailor	VERB
biomedich-176	217	14	therapies	therapy	NOUN
biomedich-176	217	15	in	in	ADP
biomedich-176	217	16	solid	solid	ADJ
biomedich-176	217	17	tumors	tumor	NOUN
biomedich-176	217	18	.	.	PUNCT
biomedich-176	218	1	molecules	molecule	NOUN
biomedich-176	218	2	,	,	PUNCT
biomedich-176	218	3	25(8	25(8	NUM
biomedich-176	218	4	)	)	PUNCT
biomedich-176	218	5	,	,	PUNCT
biomedich-176	218	6	1864	1864	NUM
biomedich-176	218	7	.	.	PUNCT
biomedich-176	219	1	chung	chung	PROPN
biomedich-176	219	2	,	,	PUNCT
biomedich-176	219	3	w.	w.	PROPN
biomedich-176	219	4	,	,	PUNCT
biomedich-176	219	5	eum	eum	PROPN
biomedich-176	219	6	,	,	PUNCT
biomedich-176	219	7	h.	h.	PROPN
biomedich-176	219	8	h.	h.	PROPN
biomedich-176	219	9	,	,	PUNCT
biomedich-176	219	10	lee	lee	PROPN
biomedich-176	219	11	,	,	PUNCT
biomedich-176	219	12	h.	h.	PROPN
biomedich-176	219	13	o.	o.	PROPN
biomedich-176	219	14	,	,	PUNCT
biomedich-176	219	15	lee	lee	PROPN
biomedich-176	219	16	,	,	PUNCT
biomedich-176	219	17	k.	k.	PROPN
biomedich-176	219	18	m.	m.	PROPN
biomedich-176	219	19	,	,	PUNCT
biomedich-176	219	20	lee	lee	PROPN
biomedich-176	219	21	,	,	PUNCT
biomedich-176	219	22	h.	h.	PROPN
biomedich-176	219	23	b.	b.	PROPN
biomedich-176	219	24	,	,	PUNCT
biomedich-176	219	25	kim	kim	PROPN
biomedich-176	219	26	,	,	PUNCT
biomedich-176	219	27	k.	k.	PROPN
biomedich-176	219	28	t.	t.	PROPN
biomedich-176	219	29	,	,	PUNCT
biomedich-176	219	30	...	...	PUNCT
biomedich-176	219	31	&	&	CCONJ
biomedich-176	219	32	kan	kan	PROPN
biomedich-176	219	33	,	,	PUNCT
biomedich-176	219	34	z.	z.	PROPN
biomedich-176	219	35	(	(	PUNCT
biomedich-176	219	36	2017	2017	NUM
biomedich-176	219	37	)	)	PUNCT
biomedich-176	219	38	.	.	PUNCT
biomedich-176	220	1	single	single	ADJ
biomedich-176	220	2	-	-	PUNCT
biomedich-176	220	3	cell	cell	NOUN
biomedich-176	220	4	rna	rna	NOUN
biomedich-176	220	5	-	-	PUNCT
biomedich-176	220	6	seq	seq	NOUN
biomedich-176	220	7	enables	enable	VERB
biomedich-176	220	8	comprehensive	comprehensive	ADJ
biomedich-176	220	9	tumour	tumour	ADJ
biomedich-176	220	10	and	and	CCONJ
biomedich-176	220	11	immune	immune	ADJ
biomedich-176	220	12	cell	cell	NOUN
biomedich-176	220	13	profiling	profiling	NOUN
biomedich-176	220	14	in	in	ADP
biomedich-176	220	15	primary	primary	ADJ
biomedich-176	220	16	breast	breast	NOUN
biomedich-176	220	17	cancer	cancer	NOUN
biomedich-176	220	18	.	.	PUNCT
biomedich-176	221	1	nature	nature	NOUN
biomedich-176	221	2	communications	communication	NOUN
biomedich-176	221	3	,	,	PUNCT
biomedich-176	221	4	8(1	8(1	NOUN
biomedich-176	221	5	)	)	PUNCT
biomedich-176	221	6	,	,	PUNCT
biomedich-176	221	7	1	1	NUM
biomedich-176	221	8	-	-	SYM
biomedich-176	221	9	12	12	NUM
biomedich-176	221	10	.	.	PUNCT
biomedich-176	222	1	climent	climent	PROPN
biomedich-176	222	2	,	,	PUNCT
biomedich-176	222	3	j.	j.	PROPN
biomedich-176	222	4	,	,	PUNCT
biomedich-176	222	5	garcia	garcia	PROPN
biomedich-176	222	6	,	,	PUNCT
biomedich-176	222	7	j.	j.	PROPN
biomedich-176	222	8	l.	l.	PROPN
biomedich-176	222	9	,	,	PUNCT
biomedich-176	222	10	mao	mao	PROPN
biomedich-176	222	11	,	,	PUNCT
biomedich-176	222	12	j.	j.	PROPN
biomedich-176	222	13	h.	h.	PROPN
biomedich-176	222	14	,	,	PUNCT
biomedich-176	222	15	arsuaga	arsuaga	PROPN
biomedich-176	222	16	,	,	PUNCT
biomedich-176	222	17	j.	j.	PROPN
biomedich-176	222	18	,	,	PUNCT
biomedich-176	222	19	&	&	CCONJ
biomedich-176	222	20	perezlosada	perezlosada	PROPN
biomedich-176	222	21	,	,	PUNCT
biomedich-176	222	22	j.	j.	PROPN
biomedich-176	222	23	(	(	PUNCT
biomedich-176	222	24	2007	2007	NUM
biomedich-176	222	25	)	)	PUNCT
biomedich-176	222	26	.	.	PUNCT
biomedich-176	223	1	characterization	characterization	NOUN
biomedich-176	223	2	of	of	ADP
biomedich-176	223	3	breast	breast	NOUN
biomedich-176	223	4	cancer	cancer	NOUN
biomedich-176	223	5	by	by	ADP
biomedich-176	223	6	array	array	NOUN
biomedich-176	223	7	comparative	comparative	ADJ
biomedich-176	223	8	genomic	genomic	NOUN
biomedich-176	223	9	hybridization	hybridization	NOUN
biomedich-176	223	10	.	.	PUNCT
biomedich-176	224	1	biochemistry	biochemistry	NOUN
biomedich-176	224	2	and	and	CCONJ
biomedich-176	224	3	cell	cell	NOUN
biomedich-176	224	4	biology	biology	NOUN
biomedich-176	224	5	,	,	PUNCT
biomedich-176	224	6	85(4	85(4	NUM
biomedich-176	224	7	)	)	PUNCT
biomedich-176	224	8	,	,	PUNCT
biomedich-176	224	9	497	497	NUM
biomedich-176	224	10	-	-	SYM
biomedich-176	224	11	508	508	NUM
biomedich-176	224	12	.	.	PUNCT
biomedich-176	225	1	cremer	cremer	NOUN
biomedich-176	225	2	,	,	PUNCT
biomedich-176	225	3	m.	m.	NOUN
biomedich-176	225	4	,	,	PUNCT
biomedich-176	225	5	grasser	grasser	PROPN
biomedich-176	225	6	,	,	PUNCT
biomedich-176	225	7	f.	f.	PROPN
biomedich-176	225	8	,	,	PUNCT
biomedich-176	225	9	lanctôt	lanctôt	PROPN
biomedich-176	225	10	,	,	PUNCT
biomedich-176	225	11	c.	c.	PROPN
biomedich-176	225	12	,	,	PUNCT
biomedich-176	225	13	müller	müller	PROPN
biomedich-176	225	14	,	,	PUNCT
biomedich-176	225	15	s.	s.	PROPN
biomedich-176	225	16	,	,	PUNCT
biomedich-176	225	17	neusser	neusser	NOUN
biomedich-176	225	18	,	,	PUNCT
biomedich-176	225	19	m.	m.	NOUN
biomedich-176	225	20	,	,	PUNCT
biomedich-176	225	21	zinner	zinner	NOUN
biomedich-176	225	22	,	,	PUNCT
biomedich-176	225	23	r.	r.	PROPN
biomedich-176	225	24	,	,	PUNCT
biomedich-176	225	25	...	...	PUNCT
biomedich-176	225	26	&	&	CCONJ
biomedich-176	225	27	cremer	cremer	PROPN
biomedich-176	225	28	,	,	PUNCT
biomedich-176	225	29	t.	t.	PROPN
biomedich-176	225	30	(	(	PUNCT
biomedich-176	225	31	2012	2012	NUM
biomedich-176	225	32	)	)	PUNCT
biomedich-176	225	33	.	.	PUNCT
biomedich-176	226	1	multicolor	multicolor	NOUN
biomedich-176	226	2	3d	3d	PROPN
biomedich-176	226	3	fluorescence	fluorescence	NOUN
biomedich-176	226	4	in	in	ADP
biomedich-176	226	5	situ	situ	ADJ
biomedich-176	226	6	hybridization	hybridization	NOUN
biomedich-176	226	7	for	for	ADP
biomedich-176	226	8	imaging	imaging	NOUN
biomedich-176	226	9	interphase	interphase	NOUN
biomedich-176	226	10	chromosomes	chromosome	NOUN
biomedich-176	226	11	.	.	PUNCT
biomedich-176	227	1	in	in	ADP
biomedich-176	227	2	the	the	DET
biomedich-176	227	3	nucleus	nucleus	NOUN
biomedich-176	227	4	(	(	PUNCT
biomedich-176	227	5	pp	pp	ADJ
biomedich-176	227	6	.	.	PUNCT
biomedich-176	228	1	205	205	NUM
biomedich-176	228	2	-	-	SYM
biomedich-176	228	3	239	239	NUM
biomedich-176	228	4	)	)	PUNCT
biomedich-176	228	5	.	.	PUNCT
biomedich-176	229	1	humana	humana	PROPN
biomedich-176	229	2	press	press	PROPN
biomedich-176	229	3	,	,	PUNCT
biomedich-176	229	4	totowa	totowa	PROPN
biomedich-176	229	5	,	,	PUNCT
biomedich-176	229	6	nj	nj	PROPN
biomedich-176	229	7	.	.	PROPN
biomedich-176	229	8	cui	cui	PROPN
biomedich-176	229	9	,	,	PUNCT
biomedich-176	229	10	c.	c.	PROPN
biomedich-176	229	11	,	,	PUNCT
biomedich-176	229	12	shu	shu	PROPN
biomedich-176	229	13	,	,	PUNCT
biomedich-176	229	14	w.	w.	PROPN
biomedich-176	229	15	,	,	PUNCT
biomedich-176	229	16	&	&	CCONJ
biomedich-176	229	17	li	li	PROPN
biomedich-176	229	18	,	,	PUNCT
biomedich-176	229	19	p.	p.	NOUN
biomedich-176	229	20	(	(	PUNCT
biomedich-176	229	21	2016	2016	NUM
biomedich-176	229	22	)	)	PUNCT
biomedich-176	229	23	.	.	PUNCT
biomedich-176	230	1	fluorescence	fluorescence	NOUN
biomedich-176	230	2	in	in	ADP
biomedich-176	230	3	situ	situ	ADJ
biomedich-176	230	4	hybridization	hybridization	NOUN
biomedich-176	230	5	:	:	PUNCT
biomedich-176	230	6	cell	cell	NOUN
biomedich-176	230	7	-	-	PUNCT
biomedich-176	230	8	based	base	VERB
biomedich-176	230	9	genetic	genetic	ADJ
biomedich-176	230	10	diagnostic	diagnostic	ADJ
biomedich-176	230	11	and	and	CCONJ
biomedich-176	230	12	research	research	NOUN
biomedich-176	230	13	applications	application	NOUN
biomedich-176	230	14	.	.	PUNCT
biomedich-176	231	1	frontiers	frontier	NOUN
biomedich-176	231	2	in	in	ADP
biomedich-176	231	3	cell	cell	NOUN
biomedich-176	231	4	and	and	CCONJ
biomedich-176	231	5	developmental	developmental	ADJ
biomedich-176	231	6	biology	biology	NOUN
biomedich-176	231	7	,	,	PUNCT
biomedich-176	231	8	4	4	NUM
biomedich-176	231	9	,	,	PUNCT
biomedich-176	231	10	89	89	NUM
biomedich-176	231	11	.	.	PUNCT
biomedich-176	231	12	da	da	PROPN
biomedich-176	231	13	silva	silva	PROPN
biomedich-176	231	14	,	,	PUNCT
biomedich-176	231	15	l.	l.	PROPN
biomedich-176	231	16	,	,	PUNCT
biomedich-176	231	17	&	&	CCONJ
biomedich-176	231	18	lakhani	lakhani	PROPN
biomedich-176	231	19	,	,	PUNCT
biomedich-176	231	20	s.	s.	PROPN
biomedich-176	231	21	r.	r.	PROPN
biomedich-176	231	22	(	(	PUNCT
biomedich-176	231	23	2010	2010	NUM
biomedich-176	231	24	)	)	PUNCT
biomedich-176	231	25	.	.	PUNCT
biomedich-176	232	1	pathology	pathology	NOUN
biomedich-176	232	2	of	of	ADP
biomedich-176	232	3	hereditary	hereditary	ADJ
biomedich-176	232	4	breast	breast	NOUN
biomedich-176	232	5	cancer	cancer	NOUN
biomedich-176	232	6	.	.	PUNCT
biomedich-176	233	1	modern	modern	ADJ
biomedich-176	233	2	pathology	pathology	NOUN
biomedich-176	233	3	,	,	PUNCT
biomedich-176	233	4	23(2	23(2	NUM
biomedich-176	233	5	)	)	PUNCT
biomedich-176	233	6	,	,	PUNCT
biomedich-176	233	7	s46	s46	NOUN
biomedich-176	233	8	-	-	PUNCT
biomedich-176	233	9	s51	s51	NOUN
biomedich-176	233	10	.	.	PUNCT
biomedich-176	234	1	daniels	daniels	PROPN
biomedich-176	234	2	,	,	PUNCT
biomedich-176	234	3	m.	m.	PROPN
biomedich-176	234	4	j.	j.	PROPN
biomedich-176	234	5	,	,	PUNCT
biomedich-176	234	6	wang	wang	PROPN
biomedich-176	234	7	,	,	PUNCT
biomedich-176	234	8	y.	y.	PROPN
biomedich-176	234	9	,	,	PUNCT
biomedich-176	234	10	lee	lee	PROPN
biomedich-176	234	11	,	,	PUNCT
biomedich-176	234	12	m.	m.	NOUN
biomedich-176	234	13	,	,	PUNCT
biomedich-176	234	14	&	&	CCONJ
biomedich-176	234	15	venkitaraman	venkitaraman	NOUN
biomedich-176	234	16	,	,	PUNCT
biomedich-176	234	17	a.	a.	PROPN
biomedich-176	234	18	r.	r.	PROPN
biomedich-176	234	19	(	(	PUNCT
biomedich-176	234	20	2004	2004	NUM
biomedich-176	234	21	)	)	PUNCT
biomedich-176	234	22	.	.	PUNCT
biomedich-176	235	1	abnormal	abnormal	ADJ
biomedich-176	235	2	cytokinesis	cytokinesis	NOUN
biomedich-176	235	3	in	in	ADP
biomedich-176	235	4	cells	cell	NOUN
biomedich-176	235	5	deficient	deficient	ADJ
biomedich-176	235	6	in	in	ADP
biomedich-176	235	7	the	the	DET
biomedich-176	235	8	breast	breast	NOUN
biomedich-176	235	9	cancer	cancer	NOUN
biomedich-176	235	10	susceptibility	susceptibility	NOUN
biomedich-176	235	11	protein	protein	NOUN
biomedich-176	235	12	brca2	brca2	PROPN
biomedich-176	235	13	.	.	PUNCT
biomedich-176	236	1	science	science	NOUN
biomedich-176	236	2	,	,	PUNCT
biomedich-176	236	3	306(5697	306(5697	NUM
biomedich-176	236	4	)	)	PUNCT
biomedich-176	236	5	,	,	PUNCT
biomedich-176	236	6	876	876	NUM
biomedich-176	236	7	-	-	SYM
biomedich-176	236	8	879	879	NUM
biomedich-176	236	9	.	.	PUNCT
biomedich-176	237	1	das	das	PROPN
biomedich-176	237	2	,	,	PUNCT
biomedich-176	237	3	k.	k.	PROPN
biomedich-176	237	4	,	,	PUNCT
biomedich-176	237	5	&	&	CCONJ
biomedich-176	237	6	tan	tan	PROPN
biomedich-176	237	7	,	,	PUNCT
biomedich-176	237	8	p.	p.	NOUN
biomedich-176	237	9	(	(	PUNCT
biomedich-176	237	10	2013	2013	NUM
biomedich-176	237	11	)	)	PUNCT
biomedich-176	237	12	.	.	PUNCT
biomedich-176	238	1	molecular	molecular	ADJ
biomedich-176	238	2	cytogenetics	cytogenetic	NOUN
biomedich-176	238	3	:	:	PUNCT
biomedich-176	238	4	recent	recent	ADJ
biomedich-176	238	5	developments	development	NOUN
biomedich-176	238	6	and	and	CCONJ
biomedich-176	238	7	applications	application	NOUN
biomedich-176	238	8	in	in	ADP
biomedich-176	238	9	cancer	cancer	NOUN
biomedich-176	238	10	.	.	PUNCT
biomedich-176	239	1	clinical	clinical	ADJ
biomedich-176	239	2	genetics	genetic	NOUN
biomedich-176	239	3	,	,	PUNCT
biomedich-176	239	4	84(4	84(4	NUM
biomedich-176	239	5	)	)	PUNCT
biomedich-176	239	6	,	,	PUNCT
biomedich-176	239	7	315	315	NUM
biomedich-176	239	8	-	-	SYM
biomedich-176	239	9	325	325	NUM
biomedich-176	239	10	.	.	PUNCT
biomedich-176	239	11	de	de	X
biomedich-176	239	12	ruijter	ruijter	NOUN
biomedich-176	239	13	,	,	PUNCT
biomedich-176	239	14	t.	t.	PROPN
biomedich-176	239	15	c.	c.	PROPN
biomedich-176	239	16	,	,	PUNCT
biomedich-176	239	17	veeck	veeck	PROPN
biomedich-176	239	18	,	,	PUNCT
biomedich-176	239	19	j.	j.	PROPN
biomedich-176	239	20	,	,	PUNCT
biomedich-176	239	21	de	de	PROPN
biomedich-176	239	22	hoon	hoon	PROPN
biomedich-176	239	23	,	,	PUNCT
biomedich-176	239	24	j.	j.	PROPN
biomedich-176	239	25	p.	p.	PROPN
biomedich-176	239	26	,	,	PUNCT
biomedich-176	239	27	van	van	PROPN
biomedich-176	239	28	engeland	engeland	PROPN
biomedich-176	239	29	,	,	PUNCT
biomedich-176	239	30	m.	m.	NOUN
biomedich-176	239	31	,	,	PUNCT
biomedich-176	239	32	&	&	CCONJ
biomedich-176	239	33	tjan	tjan	PROPN
biomedich-176	239	34	-	-	PROPN
biomedich-176	239	35	heijnen	heijnen	NOUN
biomedich-176	239	36	,	,	PUNCT
biomedich-176	239	37	v.	v.	PROPN
biomedich-176	239	38	c.	c.	PROPN
biomedich-176	239	39	(	(	PUNCT
biomedich-176	239	40	2011	2011	NUM
biomedich-176	239	41	)	)	PUNCT
biomedich-176	239	42	.	.	PUNCT
biomedich-176	240	1	characteristics	characteristic	NOUN
biomedich-176	240	2	of	of	ADP
biomedich-176	240	3	triple	triple	ADJ
biomedich-176	240	4	-	-	PUNCT
biomedich-176	240	5	negative	negative	ADJ
biomedich-176	240	6	breast	breast	NOUN
biomedich-176	240	7	cancer	cancer	NOUN
biomedich-176	240	8	.	.	PUNCT
biomedich-176	241	1	journal	journal	PROPN
biomedich-176	241	2	of	of	ADP
biomedich-176	241	3	cancer	cancer	NOUN
biomedich-176	241	4	research	research	NOUN
biomedich-176	241	5	and	and	CCONJ
biomedich-176	241	6	clinical	clinical	ADJ
biomedich-176	241	7	oncology	oncology	NOUN
biomedich-176	241	8	,	,	PUNCT
biomedich-176	241	9	137(2	137(2	NUM
biomedich-176	241	10	)	)	PUNCT
biomedich-176	241	11	,	,	PUNCT
biomedich-176	241	12	183	183	NUM
biomedich-176	241	13	-	-	SYM
biomedich-176	241	14	192	192	NUM
biomedich-176	241	15	.	.	PUNCT
biomedich-176	242	1	fiegl	fiegl	ADJ
biomedich-176	242	2	,	,	PUNCT
biomedich-176	242	3	m.	m.	NOUN
biomedich-176	242	4	,	,	PUNCT
biomedich-176	242	5	tueni	tueni	PROPN
biomedich-176	242	6	,	,	PUNCT
biomedich-176	242	7	c.	c.	PROPN
biomedich-176	242	8	,	,	PUNCT
biomedich-176	242	9	schenk	schenk	PROPN
biomedich-176	242	10	,	,	PUNCT
biomedich-176	242	11	t.	t.	PROPN
biomedich-176	242	12	,	,	PUNCT
biomedich-176	242	13	jakesz	jakesz	PROPN
biomedich-176	242	14	,	,	PUNCT
biomedich-176	242	15	r.	r.	PROPN
biomedich-176	242	16	,	,	PUNCT
biomedich-176	242	17	gnant	gnant	PROPN
biomedich-176	242	18	,	,	PUNCT
biomedich-176	242	19	m.	m.	NOUN
biomedich-176	242	20	,	,	PUNCT
biomedich-176	242	21	reiner	reiner	NOUN
biomedich-176	242	22	,	,	PUNCT
biomedich-176	242	23	a.	a.	NOUN
biomedich-176	242	24	,	,	PUNCT
biomedich-176	242	25	...	...	PUNCT
biomedich-176	242	26	&	&	CCONJ
biomedich-176	242	27	drach	drach	PROPN
biomedich-176	242	28	,	,	PUNCT
biomedich-176	242	29	j.	j.	PROPN
biomedich-176	242	30	(	(	PUNCT
biomedich-176	242	31	1995	1995	NUM
biomedich-176	242	32	)	)	PUNCT
biomedich-176	242	33	.	.	PUNCT
biomedich-176	243	1	interphase	interphase	NOUN
biomedich-176	243	2	cytogenetics	cytogenetic	NOUN
biomedich-176	243	3	reveals	reveal	VERB
biomedich-176	243	4	a	a	DET
biomedich-176	243	5	high	high	ADJ
biomedich-176	243	6	incidence	incidence	NOUN
biomedich-176	243	7	of	of	ADP
biomedich-176	243	8	aneuploidy	aneuploidy	ADJ
biomedich-176	243	9	and	and	CCONJ
biomedich-176	243	10	intra	intra	ADJ
biomedich-176	243	11	-	-	ADJ
biomedich-176	243	12	tumour	tumour	ADJ
biomedich-176	243	13	heterogeneity	heterogeneity	NOUN
biomedich-176	243	14	in	in	ADP
biomedich-176	243	15	breast	breast	NOUN
biomedich-176	243	16	cancer	cancer	NOUN
biomedich-176	243	17	.	.	PUNCT
biomedich-176	244	1	british	british	ADJ
biomedich-176	244	2	journal	journal	PROPN
biomedich-176	244	3	of	of	ADP
biomedich-176	244	4	cancer	cancer	NOUN
biomedich-176	244	5	,	,	PUNCT
biomedich-176	244	6	72(1	72(1	NOUN
biomedich-176	244	7	)	)	PUNCT
biomedich-176	244	8	,	,	PUNCT
biomedich-176	244	9	51	51	NUM
biomedich-176	244	10	-	-	SYM
biomedich-176	244	11	55	55	NUM
biomedich-176	244	12	.	.	PUNCT
biomedich-176	245	1	forozan	forozan	PROPN
biomedich-176	245	2	,	,	PUNCT
biomedich-176	245	3	f.	f.	PROPN
biomedich-176	245	4	,	,	PUNCT
biomedich-176	245	5	karhu	karhu	PROPN
biomedich-176	245	6	,	,	PUNCT
biomedich-176	245	7	r.	r.	PROPN
biomedich-176	245	8	,	,	PUNCT
biomedich-176	245	9	kononen	kononen	PROPN
biomedich-176	245	10	,	,	PUNCT
biomedich-176	245	11	j.	j.	PROPN
biomedich-176	245	12	,	,	PUNCT
biomedich-176	245	13	kallioniemi	kallioniemi	PROPN
biomedich-176	245	14	,	,	PUNCT
biomedich-176	245	15	a.	a.	PROPN
biomedich-176	245	16	,	,	PUNCT
biomedich-176	245	17	&	&	CCONJ
biomedich-176	245	18	kallioniemi	kallioniemi	PROPN
biomedich-176	245	19	,	,	PUNCT
biomedich-176	245	20	o.	o.	PROPN
biomedich-176	245	21	p.	p.	NOUN
biomedich-176	245	22	(	(	PUNCT
biomedich-176	245	23	1997	1997	NUM
biomedich-176	245	24	)	)	PUNCT
biomedich-176	245	25	.	.	PUNCT
biomedich-176	246	1	genome	genome	NOUN
biomedich-176	246	2	screening	screening	NOUN
biomedich-176	246	3	by	by	ADP
biomedich-176	246	4	comparative	comparative	ADJ
biomedich-176	246	5	genomic	genomic	ADJ
biomedich-176	246	6	hybridization	hybridization	NOUN
biomedich-176	246	7	.	.	PUNCT
biomedich-176	247	1	trends	trend	NOUN
biomedich-176	247	2	in	in	ADP
biomedich-176	247	3	genetics	genetic	NOUN
biomedich-176	247	4	,	,	PUNCT
biomedich-176	247	5	13(10	13(10	NUM
biomedich-176	247	6	)	)	PUNCT
biomedich-176	247	7	,	,	PUNCT
biomedich-176	247	8	405	405	NUM
biomedich-176	247	9	-	-	SYM
biomedich-176	247	10	409	409	NUM
biomedich-176	247	11	.	.	PUNCT
biomedich-176	248	1	forozan	forozan	PROPN
biomedich-176	248	2	,	,	PUNCT
biomedich-176	248	3	f.	f.	PROPN
biomedich-176	248	4	,	,	PUNCT
biomedich-176	248	5	mahlamäki	mahlamäki	PROPN
biomedich-176	248	6	,	,	PUNCT
biomedich-176	248	7	e.	e.	PROPN
biomedich-176	248	8	h.	h.	PROPN
biomedich-176	248	9	,	,	PUNCT
biomedich-176	248	10	monni	monni	PROPN
biomedich-176	248	11	,	,	PUNCT
biomedich-176	248	12	o.	o.	PROPN
biomedich-176	248	13	,	,	PUNCT
biomedich-176	248	14	chen	chen	PROPN
biomedich-176	248	15	,	,	PUNCT
biomedich-176	248	16	y.	y.	PROPN
biomedich-176	248	17	,	,	PUNCT
biomedich-176	248	18	veldman	veldman	PROPN
biomedich-176	248	19	,	,	PUNCT
biomedich-176	248	20	r.	r.	PROPN
biomedich-176	248	21	,	,	PUNCT
biomedich-176	248	22	jiang	jiang	PROPN
biomedich-176	248	23	,	,	PUNCT
biomedich-176	248	24	y.	y.	PROPN
biomedich-176	248	25	,	,	PUNCT
biomedich-176	248	26	...	...	PUNCT
biomedich-176	248	27	&	&	CCONJ
biomedich-176	248	28	kallioniemi	kallioniemi	PROPN
biomedich-176	248	29	,	,	PUNCT
biomedich-176	248	30	o.	o.	PROPN
biomedich-176	248	31	p.	p.	NOUN
biomedich-176	248	32	(	(	PUNCT
biomedich-176	248	33	2000	2000	NUM
biomedich-176	248	34	)	)	PUNCT
biomedich-176	248	35	.	.	PUNCT
biomedich-176	249	1	comparative	comparative	ADJ
biomedich-176	249	2	genomic	genomic	ADJ
biomedich-176	249	3	hybridization	hybridization	NOUN
biomedich-176	249	4	analysis	analysis	NOUN
biomedich-176	249	5	of	of	ADP
biomedich-176	249	6	38	38	NUM
biomedich-176	249	7	breast	breast	NOUN
biomedich-176	249	8	cancer	cancer	NOUN
biomedich-176	249	9	cell	cell	NOUN
biomedich-176	249	10	lines	line	NOUN
biomedich-176	249	11	:	:	PUNCT
biomedich-176	249	12	a	a	DET
biomedich-176	249	13	basis	basis	NOUN
biomedich-176	249	14	for	for	ADP
biomedich-176	249	15	interpreting	interpret	VERB
biomedich-176	249	16	complementary	complementary	ADJ
biomedich-176	249	17	dna	dna	PROPN
biomedich-176	249	18	microarray	microarray	PROPN
biomedich-176	249	19	data	datum	NOUN
biomedich-176	249	20	.	.	PUNCT
biomedich-176	250	1	cancer	cancer	NOUN
biomedich-176	250	2	research	research	NOUN
biomedich-176	250	3	,	,	PUNCT
biomedich-176	250	4	60(16	60(16	NOUN
biomedich-176	250	5	)	)	PUNCT
biomedich-176	250	6	,	,	PUNCT
biomedich-176	250	7	4519	4519	NUM
biomedich-176	250	8	-	-	SYM
biomedich-176	250	9	4525	4525	NUM
biomedich-176	250	10	.	.	PUNCT
biomedich-176	251	1	giollant	giollant	PROPN
biomedich-176	251	2	,	,	PUNCT
biomedich-176	251	3	m.	m.	NOUN
biomedich-176	251	4	,	,	PUNCT
biomedich-176	251	5	bertrand	bertrand	PROPN
biomedich-176	251	6	,	,	PUNCT
biomedich-176	251	7	s.	s.	PROPN
biomedich-176	251	8	,	,	PUNCT
biomedich-176	251	9	verrelle	verrelle	NOUN
biomedich-176	251	10	,	,	PUNCT
biomedich-176	251	11	p.	p.	NOUN
biomedich-176	251	12	,	,	PUNCT
biomedich-176	251	13	tchirkov	tchirkov	PROPN
biomedich-176	251	14	,	,	PUNCT
biomedich-176	251	15	a.	a.	PROPN
biomedich-176	251	16	,	,	PUNCT
biomedich-176	251	17	du	du	PROPN
biomedich-176	251	18	manoir	manoir	PROPN
biomedich-176	251	19	,	,	PUNCT
biomedich-176	251	20	s.	s.	PROPN
biomedich-176	251	21	,	,	PUNCT
biomedich-176	251	22	ried	rie	VERB
biomedich-176	251	23	,	,	PUNCT
biomedich-176	251	24	t.	t.	PROPN
biomedich-176	251	25	,	,	PUNCT
biomedich-176	251	26	...	...	PUNCT
biomedich-176	251	27	&	&	CCONJ
biomedich-176	251	28	tchirkov	tchirkov	PROPN
biomedich-176	251	29	,	,	PUNCT
biomedich-176	251	30	a.	a.	NOUN
biomedich-176	251	31	(	(	PUNCT
biomedich-176	251	32	1996	1996	NUM
biomedich-176	251	33	)	)	PUNCT
biomedich-176	251	34	.	.	PUNCT
biomedich-176	252	1	characterization	characterization	NOUN
biomedich-176	252	2	of	of	ADP
biomedich-176	252	3	double	double	ADJ
biomedich-176	252	4	minute	minute	NOUN
biomedich-176	252	5	chromosomes	chromosome	NOUN
biomedich-176	252	6	'	'	PART
biomedich-176	252	7	dna	dna	PROPN
biomedich-176	252	8	content	content	NOUN
biomedich-176	252	9	in	in	ADP
biomedich-176	252	10	a	a	DET
biomedich-176	252	11	human	human	ADJ
biomedich-176	252	12	high	high	ADJ
biomedich-176	252	13	grade	grade	NOUN
biomedich-176	252	14	astrocytoma	astrocytoma	NOUN
biomedich-176	252	15	cell	cell	NOUN
biomedich-176	252	16	line	line	NOUN
biomedich-176	252	17	by	by	ADP
biomedich-176	252	18	using	use	VERB
biomedich-176	252	19	comparative	comparative	ADJ
biomedich-176	252	20	genomic	genomic	NOUN
biomedich-176	252	21	hybridization	hybridization	NOUN
biomedich-176	252	22	and	and	CCONJ
biomedich-176	252	23	fluorescence	fluorescence	NOUN
biomedich-176	252	24	in	in	ADP
biomedich-176	252	25	situ	situ	ADJ
biomedich-176	252	26	hybridization	hybridization	NOUN
biomedich-176	252	27	.	.	PUNCT
biomedich-176	253	1	human	human	ADJ
biomedich-176	253	2	genetics	genetic	NOUN
biomedich-176	253	3	,	,	PUNCT
biomedich-176	253	4	98(3	98(3	PROPN
biomedich-176	253	5	)	)	PUNCT
biomedich-176	253	6	,	,	PUNCT
biomedich-176	253	7	265	265	NUM
biomedich-176	253	8	-	-	SYM
biomedich-176	253	9	270	270	NUM
biomedich-176	253	10	.	.	PUNCT
biomedich-176	254	1	gozzetti	gozzetti	NOUN
biomedich-176	254	2	,	,	PUNCT
biomedich-176	254	3	a.	a.	NOUN
biomedich-176	254	4	,	,	PUNCT
biomedich-176	254	5	&	&	CCONJ
biomedich-176	254	6	le	le	X
biomedich-176	254	7	beau	beau	PROPN
biomedich-176	254	8	,	,	PUNCT
biomedich-176	254	9	m.	m.	NOUN
biomedich-176	254	10	m.	m.	NOUN
biomedich-176	254	11	(	(	PUNCT
biomedich-176	254	12	2000	2000	NUM
biomedich-176	254	13	,	,	PUNCT
biomedich-176	254	14	october	october	PROPN
biomedich-176	254	15	)	)	PUNCT
biomedich-176	254	16	.	.	PUNCT
biomedich-176	255	1	fluorescence	fluorescence	NOUN
biomedich-176	255	2	in	in	ADP
biomedich-176	255	3	situ	situ	ADJ
biomedich-176	255	4	hybridization	hybridization	NOUN
biomedich-176	255	5	:	:	PUNCT
biomedich-176	255	6	uses	use	NOUN
biomedich-176	255	7	and	and	CCONJ
biomedich-176	255	8	limitations	limitation	NOUN
biomedich-176	255	9	.	.	PUNCT
biomedich-176	256	1	in	in	ADP
biomedich-176	256	2	seminars	seminar	NOUN
biomedich-176	256	3	in	in	ADP
biomedich-176	256	4	hematology	hematology	NOUN
biomedich-176	256	5	(	(	PUNCT
biomedich-176	256	6	vol	vol	NOUN
biomedich-176	256	7	.	.	PROPN
biomedich-176	256	8	37	37	NUM
biomedich-176	256	9	,	,	PUNCT
biomedich-176	256	10	no	no	INTJ
biomedich-176	256	11	.	.	NOUN
biomedich-176	256	12	4	4	NUM
biomedich-176	256	13	,	,	PUNCT
biomedich-176	256	14	pp	pp	ADJ
biomedich-176	256	15	.	.	PUNCT
biomedich-176	256	16	320	320	NUM
biomedich-176	256	17	-	-	SYM
biomedich-176	256	18	333	333	NUM
biomedich-176	256	19	)	)	PUNCT
biomedich-176	256	20	.	.	PUNCT
biomedich-176	257	1	wb	wb	PROPN
biomedich-176	257	2	saunders	saunders	PROPN
biomedich-176	257	3	.	.	PUNCT
biomedich-176	258	1	smail	smail	NOUN
biomedich-176	258	2	–	–	PUNCT
biomedich-176	258	3	the	the	DET
biomedich-176	258	4	roles	role	NOUN
biomedich-176	258	5	of	of	ADP
biomedich-176	258	6	the	the	DET
biomedich-176	258	7	fluorescent	fluorescent	NOUN
biomedich-176	258	8	in	in	ADP
biomedich-176	258	9	situ	situ	ADJ
biomedich-176	258	10	hybridization	hybridization	NOUN
biomedich-176	258	11	(	(	PUNCT
biomedich-176	258	12	fish	fish	NOUN
biomedich-176	258	13	)	)	PUNCT
biomedich-176	258	14	and	and	CCONJ
biomedich-176	258	15	…	…	PUNCT
biomedich-176	258	16	53	53	NUM
biomedich-176	258	17	gozzetti	gozzetti	NOUN
biomedich-176	258	18	,	,	PUNCT
biomedich-176	258	19	a.	a.	NOUN
biomedich-176	258	20	,	,	PUNCT
biomedich-176	258	21	&	&	CCONJ
biomedich-176	258	22	le	le	X
biomedich-176	258	23	beau	beau	PROPN
biomedich-176	258	24	,	,	PUNCT
biomedich-176	258	25	m.	m.	NOUN
biomedich-176	258	26	m.	m.	NOUN
biomedich-176	258	27	(	(	PUNCT
biomedich-176	258	28	2000	2000	NUM
biomedich-176	258	29	,	,	PUNCT
biomedich-176	258	30	october	october	PROPN
biomedich-176	258	31	)	)	PUNCT
biomedich-176	258	32	.	.	PUNCT
biomedich-176	259	1	fluorescence	fluorescence	NOUN
biomedich-176	259	2	in	in	ADP
biomedich-176	259	3	situ	situ	ADJ
biomedich-176	259	4	hybridization	hybridization	NOUN
biomedich-176	259	5	:	:	PUNCT
biomedich-176	259	6	uses	use	NOUN
biomedich-176	259	7	and	and	CCONJ
biomedich-176	259	8	limitations	limitation	NOUN
biomedich-176	259	9	.	.	PUNCT
biomedich-176	260	1	in	in	ADP
biomedich-176	260	2	seminars	seminar	NOUN
biomedich-176	260	3	in	in	ADP
biomedich-176	260	4	hematology	hematology	NOUN
biomedich-176	260	5	(	(	PUNCT
biomedich-176	260	6	vol	vol	NOUN
biomedich-176	260	7	.	.	PROPN
biomedich-176	260	8	37	37	NUM
biomedich-176	260	9	,	,	PUNCT
biomedich-176	260	10	no	no	INTJ
biomedich-176	260	11	.	.	NOUN
biomedich-176	260	12	4	4	NUM
biomedich-176	260	13	,	,	PUNCT
biomedich-176	260	14	pp	pp	ADJ
biomedich-176	260	15	.	.	PUNCT
biomedich-176	260	16	320	320	NUM
biomedich-176	260	17	-	-	SYM
biomedich-176	260	18	333	333	NUM
biomedich-176	260	19	)	)	PUNCT
biomedich-176	260	20	.	.	PUNCT
biomedich-176	261	1	wb	wb	PROPN
biomedich-176	261	2	saunders	saunders	PROPN
biomedich-176	261	3	.	.	PUNCT
biomedich-176	262	1	hovhannisyan	hovhannisyan	PROPN
biomedich-176	262	2	,	,	PUNCT
biomedich-176	262	3	g.	g.	PROPN
biomedich-176	262	4	g.	g.	PROPN
biomedich-176	262	5	(	(	PUNCT
biomedich-176	262	6	2010	2010	NUM
biomedich-176	262	7	)	)	PUNCT
biomedich-176	262	8	.	.	PUNCT
biomedich-176	263	1	fluorescence	fluorescence	NOUN
biomedich-176	263	2	in	in	ADP
biomedich-176	263	3	situ	situ	ADJ
biomedich-176	263	4	hybridization	hybridization	NOUN
biomedich-176	263	5	in	in	ADP
biomedich-176	263	6	combination	combination	NOUN
biomedich-176	263	7	with	with	ADP
biomedich-176	263	8	the	the	DET
biomedich-176	263	9	comet	comet	NOUN
biomedich-176	263	10	assay	assay	VERB
biomedich-176	263	11	and	and	CCONJ
biomedich-176	263	12	micronucleus	micronucleus	PROPN
biomedich-176	263	13	test	test	NOUN
biomedich-176	263	14	in	in	ADP
biomedich-176	263	15	genetic	genetic	ADJ
biomedich-176	263	16	toxicology	toxicology	NOUN
biomedich-176	263	17	.	.	PUNCT
biomedich-176	264	1	molecular	molecular	ADJ
biomedich-176	264	2	cytogenetics	cytogenetic	NOUN
biomedich-176	264	3	,	,	PUNCT
biomedich-176	264	4	3(1	3(1	NUM
biomedich-176	264	5	)	)	PUNCT
biomedich-176	264	6	,	,	PUNCT
biomedich-176	264	7	17	17	NUM
biomedich-176	264	8	.	.	PUNCT
biomedich-176	265	1	howlader	howlader	PROPN
biomedich-176	265	2	,	,	PUNCT
biomedich-176	265	3	n.	n.	NOUN
biomedich-176	265	4	,	,	PUNCT
biomedich-176	265	5	altekruse	altekruse	PROPN
biomedich-176	265	6	,	,	PUNCT
biomedich-176	265	7	s.	s.	PROPN
biomedich-176	265	8	f.	f.	PROPN
biomedich-176	265	9	,	,	PUNCT
biomedich-176	265	10	li	li	PROPN
biomedich-176	265	11	,	,	PUNCT
biomedich-176	265	12	c.	c.	PROPN
biomedich-176	265	13	i.	i.	PROPN
biomedich-176	265	14	,	,	PUNCT
biomedich-176	265	15	chen	chen	PROPN
biomedich-176	265	16	,	,	PUNCT
biomedich-176	265	17	v.	v.	PROPN
biomedich-176	265	18	w.	w.	PROPN
biomedich-176	265	19	,	,	PUNCT
biomedich-176	265	20	clarke	clarke	PROPN
biomedich-176	265	21	,	,	PUNCT
biomedich-176	265	22	c.	c.	PROPN
biomedich-176	265	23	a.	a.	PROPN
biomedich-176	265	24	,	,	PUNCT
biomedich-176	265	25	ries	rie	NOUN
biomedich-176	265	26	,	,	PUNCT
biomedich-176	265	27	l.	l.	PROPN
biomedich-176	265	28	a.	a.	PROPN
biomedich-176	265	29	,	,	PUNCT
biomedich-176	265	30	&	&	CCONJ
biomedich-176	265	31	cronin	cronin	PROPN
biomedich-176	265	32	,	,	PUNCT
biomedich-176	265	33	k.	k.	PROPN
biomedich-176	265	34	a.	a.	PROPN
biomedich-176	266	1	(	(	PUNCT
biomedich-176	266	2	2014	2014	NUM
biomedich-176	266	3	)	)	PUNCT
biomedich-176	266	4	.	.	PUNCT
biomedich-176	267	1	us	we	PRON
biomedich-176	267	2	incidence	incidence	NOUN
biomedich-176	267	3	of	of	ADP
biomedich-176	267	4	breast	breast	NOUN
biomedich-176	267	5	cancer	cancer	NOUN
biomedich-176	267	6	subtypes	subtype	NOUN
biomedich-176	267	7	defined	define	VERB
biomedich-176	267	8	by	by	ADP
biomedich-176	267	9	joint	joint	ADJ
biomedich-176	267	10	hormone	hormone	NOUN
biomedich-176	267	11	receptor	receptor	NOUN
biomedich-176	267	12	and	and	CCONJ
biomedich-176	267	13	her2	her2	PROPN
biomedich-176	267	14	status	status	NOUN
biomedich-176	267	15	.	.	PUNCT
biomedich-176	268	1	jnci	jnci	PROPN
biomedich-176	268	2	:	:	PUNCT
biomedich-176	268	3	journal	journal	NOUN
biomedich-176	268	4	of	of	ADP
biomedich-176	268	5	the	the	DET
biomedich-176	268	6	national	national	PROPN
biomedich-176	268	7	cancer	cancer	PROPN
biomedich-176	268	8	institute	institute	PROPN
biomedich-176	268	9	,	,	PUNCT
biomedich-176	268	10	106(5	106(5	NUM
biomedich-176	268	11	)	)	PUNCT
biomedich-176	268	12	.	.	PUNCT
biomedich-176	269	1	hu	hu	PROPN
biomedich-176	269	2	,	,	PUNCT
biomedich-176	269	3	q.	q.	PROPN
biomedich-176	269	4	,	,	PUNCT
biomedich-176	269	5	maurais	maurais	PROPN
biomedich-176	269	6	,	,	PUNCT
biomedich-176	269	7	e.	e.	PROPN
biomedich-176	269	8	g.	g.	PROPN
biomedich-176	269	9	,	,	PUNCT
biomedich-176	269	10	&	&	CCONJ
biomedich-176	269	11	ly	ly	PROPN
biomedich-176	269	12	,	,	PUNCT
biomedich-176	269	13	p.	p.	NOUN
biomedich-176	269	14	(	(	PUNCT
biomedich-176	269	15	2020	2020	NUM
biomedich-176	269	16	)	)	PUNCT
biomedich-176	269	17	.	.	PUNCT
biomedich-176	270	1	cellular	cellular	ADJ
biomedich-176	270	2	and	and	CCONJ
biomedich-176	270	3	genomic	genomic	NOUN
biomedich-176	270	4	approaches	approach	NOUN
biomedich-176	270	5	for	for	ADP
biomedich-176	270	6	exploring	explore	VERB
biomedich-176	270	7	structural	structural	ADJ
biomedich-176	270	8	chromosomal	chromosomal	ADJ
biomedich-176	270	9	rearrangements	rearrangement	NOUN
biomedich-176	270	10	.	.	PUNCT
biomedich-176	271	1	chromosome	chromosome	NOUN
biomedich-176	271	2	research	research	NOUN
biomedich-176	271	3	,	,	PUNCT
biomedich-176	271	4	1	1	NUM
biomedich-176	271	5	-	-	SYM
biomedich-176	271	6	12	12	NUM
biomedich-176	271	7	.	.	PUNCT
biomedich-176	272	1	huber	huber	PROPN
biomedich-176	272	2	,	,	PUNCT
biomedich-176	272	3	d.	d.	PROPN
biomedich-176	272	4	,	,	PUNCT
biomedich-176	272	5	von	von	PROPN
biomedich-176	272	6	voithenberg	voithenberg	PROPN
biomedich-176	272	7	,	,	PUNCT
biomedich-176	272	8	l.	l.	PROPN
biomedich-176	272	9	v.	v.	PROPN
biomedich-176	272	10	,	,	PUNCT
biomedich-176	272	11	&	&	CCONJ
biomedich-176	272	12	kaigala	kaigala	PROPN
biomedich-176	272	13	,	,	PUNCT
biomedich-176	272	14	g.	g.	PROPN
biomedich-176	272	15	v.	v.	PROPN
biomedich-176	272	16	(	(	PUNCT
biomedich-176	272	17	2018	2018	NUM
biomedich-176	272	18	)	)	PUNCT
biomedich-176	272	19	.	.	PUNCT
biomedich-176	273	1	fluorescence	fluorescence	NOUN
biomedich-176	273	2	in	in	ADP
biomedich-176	273	3	situ	situ	ADJ
biomedich-176	273	4	hybridization	hybridization	NOUN
biomedich-176	273	5	(	(	PUNCT
biomedich-176	273	6	fish	fish	NOUN
biomedich-176	273	7	):	):	PUNCT
biomedich-176	273	8	history	history	NOUN
biomedich-176	273	9	,	,	PUNCT
biomedich-176	273	10	limitations	limitation	NOUN
biomedich-176	273	11	and	and	CCONJ
biomedich-176	273	12	what	what	PRON
biomedich-176	273	13	to	to	PART
biomedich-176	273	14	expect	expect	VERB
biomedich-176	273	15	from	from	ADP
biomedich-176	273	16	micro	micro	ADJ
biomedich-176	273	17	-	-	NOUN
biomedich-176	273	18	scale	scale	ADJ
biomedich-176	273	19	fish	fish	NOUN
biomedich-176	273	20	?	?	PUNCT
biomedich-176	273	21	.	.	PUNCT
biomedich-176	274	1	micro	micro	PROPN
biomedich-176	274	2	and	and	CCONJ
biomedich-176	274	3	nano	nano	PROPN
biomedich-176	274	4	engineering	engineering	NOUN
biomedich-176	274	5	,	,	PUNCT
biomedich-176	274	6	1	1	NUM
biomedich-176	274	7	,	,	PUNCT
biomedich-176	274	8	15	15	NUM
biomedich-176	274	9	-	-	SYM
biomedich-176	274	10	24	24	NUM
biomedich-176	274	11	.	.	PUNCT
biomedich-176	275	1	hyytinen	hyytinen	PROPN
biomedich-176	275	2	,	,	PUNCT
biomedich-176	275	3	e.	e.	PROPN
biomedich-176	275	4	,	,	PUNCT
biomedich-176	275	5	visakorpi	visakorpi	NOUN
biomedich-176	275	6	,	,	PUNCT
biomedich-176	275	7	t.	t.	PROPN
biomedich-176	275	8	,	,	PUNCT
biomedich-176	275	9	kallioniemi	kallioniemi	PROPN
biomedich-176	275	10	,	,	PUNCT
biomedich-176	275	11	a.	a.	PROPN
biomedich-176	275	12	,	,	PUNCT
biomedich-176	275	13	kallioniemi	kallioniemi	PROPN
biomedich-176	275	14	,	,	PUNCT
biomedich-176	275	15	o.	o.	PROPN
biomedich-176	275	16	p.	p.	PROPN
biomedich-176	275	17	,	,	PUNCT
biomedich-176	275	18	&	&	CCONJ
biomedich-176	275	19	isola	isola	PROPN
biomedich-176	275	20	,	,	PUNCT
biomedich-176	275	21	j.	j.	PROPN
biomedich-176	275	22	j.	j.	PROPN
biomedich-176	275	23	(	(	PUNCT
biomedich-176	275	24	1994	1994	NUM
biomedich-176	275	25	)	)	PUNCT
biomedich-176	275	26	.	.	PUNCT
biomedich-176	276	1	improved	improve	VERB
biomedich-176	276	2	technique	technique	NOUN
biomedich-176	276	3	for	for	ADP
biomedich-176	276	4	analysis	analysis	NOUN
biomedich-176	276	5	of	of	ADP
biomedich-176	276	6	formalin‐fixed	formalin‐fixed	ADJ
biomedich-176	276	7	,	,	PUNCT
biomedich-176	276	8	paraffin‐embedded	paraffin‐embedded	ADJ
biomedich-176	276	9	tumors	tumor	NOUN
biomedich-176	276	10	by	by	ADP
biomedich-176	276	11	fluorescence	fluorescence	NOUN
biomedich-176	276	12	in	in	ADP
biomedich-176	276	13	situ	situ	ADJ
biomedich-176	276	14	hybridization	hybridization	NOUN
biomedich-176	276	15	.	.	PUNCT
biomedich-176	277	1	cytometry	cytometry	NOUN
biomedich-176	277	2	:	:	PUNCT
biomedich-176	277	3	the	the	DET
biomedich-176	277	4	journal	journal	NOUN
biomedich-176	277	5	of	of	ADP
biomedich-176	277	6	the	the	DET
biomedich-176	277	7	international	international	ADJ
biomedich-176	277	8	society	society	NOUN
biomedich-176	277	9	for	for	ADP
biomedich-176	277	10	analytical	analytical	ADJ
biomedich-176	277	11	cytology	cytology	NOUN
biomedich-176	277	12	,	,	PUNCT
biomedich-176	277	13	16(2	16(2	NUM
biomedich-176	277	14	)	)	PUNCT
biomedich-176	277	15	,	,	PUNCT
biomedich-176	277	16	93	93	NUM
biomedich-176	277	17	-	-	SYM
biomedich-176	277	18	99	99	NUM
biomedich-176	277	19	.	.	PUNCT
biomedich-176	278	1	jacobsen	jacobsen	PROPN
biomedich-176	278	2	,	,	PUNCT
biomedich-176	278	3	a.	a.	PROPN
biomedich-176	278	4	,	,	PUNCT
biomedich-176	278	5	arnold	arnold	PROPN
biomedich-176	278	6	,	,	PUNCT
biomedich-176	278	7	n.	n.	PROPN
biomedich-176	278	8	,	,	PUNCT
biomedich-176	278	9	weimer	weimer	PROPN
biomedich-176	278	10	,	,	PUNCT
biomedich-176	278	11	j.	j.	PROPN
biomedich-176	278	12	,	,	PUNCT
biomedich-176	278	13	&	&	CCONJ
biomedich-176	278	14	kiechle	kiechle	PROPN
biomedich-176	278	15	,	,	PUNCT
biomedich-176	278	16	m.	m.	NOUN
biomedich-176	278	17	(	(	PUNCT
biomedich-176	278	18	2000	2000	NUM
biomedich-176	278	19	)	)	PUNCT
biomedich-176	278	20	.	.	PUNCT
biomedich-176	279	1	comparison	comparison	NOUN
biomedich-176	279	2	of	of	ADP
biomedich-176	279	3	comparative	comparative	ADJ
biomedich-176	279	4	genomic	genomic	NOUN
biomedich-176	279	5	hybridization	hybridization	NOUN
biomedich-176	279	6	and	and	CCONJ
biomedich-176	279	7	interphase	interphase	ADJ
biomedich-176	279	8	fluorescence	fluorescence	NOUN
biomedich-176	279	9	in	in	ADP
biomedich-176	279	10	situ	situ	ADJ
biomedich-176	279	11	hybridization	hybridization	NOUN
biomedich-176	279	12	in	in	ADP
biomedich-176	279	13	ovarian	ovarian	ADJ
biomedich-176	279	14	carcinomas	carcinoma	NOUN
biomedich-176	279	15	:	:	PUNCT
biomedich-176	279	16	possibilities	possibility	NOUN
biomedich-176	279	17	and	and	CCONJ
biomedich-176	279	18	limitations	limitation	NOUN
biomedich-176	279	19	of	of	ADP
biomedich-176	279	20	both	both	DET
biomedich-176	279	21	techniques	technique	NOUN
biomedich-176	279	22	.	.	PUNCT
biomedich-176	280	1	cancer	cancer	NOUN
biomedich-176	280	2	genetics	genetic	NOUN
biomedich-176	280	3	and	and	CCONJ
biomedich-176	280	4	cytogenetics	cytogenetic	NOUN
biomedich-176	280	5	,	,	PUNCT
biomedich-176	280	6	122(1	122(1	NUM
biomedich-176	280	7	)	)	PUNCT
biomedich-176	280	8	,	,	PUNCT
biomedich-176	280	9	7	7	NUM
biomedich-176	280	10	-	-	SYM
biomedich-176	280	11	12	12	NUM
biomedich-176	280	12	.	.	PUNCT
biomedich-176	281	1	karimi	karimi	PROPN
biomedich-176	281	2	-	-	PUNCT
biomedich-176	281	3	nejhad	nejhad	PROPN
biomedich-176	281	4	,	,	PUNCT
biomedich-176	281	5	r.	r.	PROPN
biomedich-176	281	6	,	,	PUNCT
biomedich-176	281	7	&	&	CCONJ
biomedich-176	281	8	ghanadan	ghanadan	PROPN
biomedich-176	281	9	,	,	PUNCT
biomedich-176	281	10	a.	a.	NOUN
biomedich-176	281	11	(	(	PUNCT
biomedich-176	281	12	2020	2020	NUM
biomedich-176	281	13	)	)	PUNCT
biomedich-176	281	14	.	.	PUNCT
biomedich-176	282	1	fluorescent	fluorescent	NOUN
biomedich-176	282	2	in	in	ADP
biomedich-176	282	3	situ	situ	ADJ
biomedich-176	282	4	hybridization	hybridization	NOUN
biomedich-176	282	5	:	:	PUNCT
biomedich-176	282	6	methods	method	NOUN
biomedich-176	282	7	and	and	CCONJ
biomedich-176	282	8	application	application	NOUN
biomedich-176	282	9	in	in	ADP
biomedich-176	282	10	cancer	cancer	NOUN
biomedich-176	282	11	diagnosis	diagnosis	NOUN
biomedich-176	282	12	.	.	PUNCT
biomedich-176	283	1	in	in	ADP
biomedich-176	283	2	cancer	cancer	NOUN
biomedich-176	283	3	immunology	immunology	NOUN
biomedich-176	283	4	(	(	PUNCT
biomedich-176	283	5	pp	pp	ADJ
biomedich-176	283	6	.	.	PUNCT
biomedich-176	284	1	711	711	NUM
biomedich-176	284	2	-	-	SYM
biomedich-176	284	3	728	728	NUM
biomedich-176	284	4	)	)	PUNCT
biomedich-176	284	5	.	.	PUNCT
biomedich-176	285	1	springer	springer	NOUN
biomedich-176	285	2	,	,	PUNCT
biomedich-176	285	3	cham	cham	PROPN
biomedich-176	285	4	.	.	PUNCT
biomedich-176	286	1	key	key	ADJ
biomedich-176	286	2	,	,	PUNCT
biomedich-176	286	3	t.	t.	PROPN
biomedich-176	286	4	j.	j.	PROPN
biomedich-176	286	5	,	,	PUNCT
biomedich-176	286	6	verkasalo	verkasalo	PROPN
biomedich-176	286	7	,	,	PUNCT
biomedich-176	286	8	p.	p.	PROPN
biomedich-176	286	9	k.	k.	PROPN
biomedich-176	286	10	,	,	PUNCT
biomedich-176	286	11	&	&	CCONJ
biomedich-176	286	12	banks	banks	PROPN
biomedich-176	286	13	,	,	PUNCT
biomedich-176	286	14	e.	e.	PROPN
biomedich-176	286	15	(	(	PUNCT
biomedich-176	286	16	2001	2001	NUM
biomedich-176	286	17	)	)	PUNCT
biomedich-176	286	18	.	.	PUNCT
biomedich-176	287	1	epidemiology	epidemiology	NOUN
biomedich-176	287	2	of	of	ADP
biomedich-176	287	3	breast	breast	NOUN
biomedich-176	287	4	cancer	cancer	NOUN
biomedich-176	287	5	.	.	PUNCT
biomedich-176	288	1	the	the	DET
biomedich-176	288	2	lancet	lancet	PROPN
biomedich-176	288	3	oncology	oncology	NOUN
biomedich-176	288	4	,	,	PUNCT
biomedich-176	288	5	2(3	2(3	NUM
biomedich-176	288	6	)	)	PUNCT
biomedich-176	288	7	,	,	PUNCT
biomedich-176	288	8	133	133	NUM
biomedich-176	288	9	-	-	SYM
biomedich-176	288	10	140	140	NUM
biomedich-176	288	11	.	.	PUNCT
biomedich-176	289	1	kim	kim	PROPN
biomedich-176	289	2	,	,	PUNCT
biomedich-176	289	3	h.	h.	PROPN
biomedich-176	289	4	,	,	PUNCT
biomedich-176	289	5	yoo	yoo	PROPN
biomedich-176	289	6	,	,	PUNCT
biomedich-176	289	7	s.	s.	PROPN
biomedich-176	289	8	b.	b.	PROPN
biomedich-176	289	9	,	,	PUNCT
biomedich-176	289	10	choe	choe	PROPN
biomedich-176	289	11	,	,	PUNCT
biomedich-176	289	12	j.	j.	PROPN
biomedich-176	289	13	y.	y.	PROPN
biomedich-176	289	14	,	,	PUNCT
biomedich-176	289	15	paik	paik	PROPN
biomedich-176	289	16	,	,	PUNCT
biomedich-176	289	17	j.	j.	PROPN
biomedich-176	289	18	h.	h.	PROPN
biomedich-176	289	19	,	,	PUNCT
biomedich-176	289	20	xu	xu	PROPN
biomedich-176	289	21	,	,	PUNCT
biomedich-176	289	22	x.	x.	NOUN
biomedich-176	289	23	,	,	PUNCT
biomedich-176	289	24	nitta	nitta	PROPN
biomedich-176	289	25	,	,	PUNCT
biomedich-176	289	26	h.	h.	PROPN
biomedich-176	289	27	,	,	PUNCT
biomedich-176	289	28	...	...	PUNCT
biomedich-176	289	29	&	&	CCONJ
biomedich-176	289	30	chung	chung	PROPN
biomedich-176	289	31	,	,	PUNCT
biomedich-176	289	32	j.	j.	PROPN
biomedich-176	289	33	h.	h.	PROPN
biomedich-176	289	34	(	(	PUNCT
biomedich-176	289	35	2011	2011	NUM
biomedich-176	289	36	)	)	PUNCT
biomedich-176	289	37	.	.	PUNCT
biomedich-176	290	1	detection	detection	NOUN
biomedich-176	290	2	of	of	ADP
biomedich-176	290	3	alk	alk	NOUN
biomedich-176	290	4	gene	gene	NOUN
biomedich-176	290	5	rearrangement	rearrangement	NOUN
biomedich-176	290	6	in	in	ADP
biomedich-176	290	7	non	non	ADJ
biomedich-176	290	8	-	-	ADJ
biomedich-176	290	9	small	small	ADJ
biomedich-176	290	10	cell	cell	NOUN
biomedich-176	290	11	lung	lung	NOUN
biomedich-176	290	12	cancer	cancer	NOUN
biomedich-176	290	13	:	:	PUNCT
biomedich-176	290	14	a	a	DET
biomedich-176	290	15	comparison	comparison	NOUN
biomedich-176	290	16	of	of	ADP
biomedich-176	290	17	fluorescence	fluorescence	NOUN
biomedich-176	290	18	in	in	ADP
biomedich-176	290	19	situ	situ	ADJ
biomedich-176	290	20	hybridization	hybridization	NOUN
biomedich-176	290	21	and	and	CCONJ
biomedich-176	290	22	chromogenic	chromogenic	ADJ
biomedich-176	290	23	in	in	ADP
biomedich-176	290	24	situ	situ	ADJ
biomedich-176	290	25	hybridization	hybridization	NOUN
biomedich-176	290	26	with	with	ADP
biomedich-176	290	27	correlation	correlation	NOUN
biomedich-176	290	28	of	of	ADP
biomedich-176	290	29	alk	alk	NOUN
biomedich-176	290	30	protein	protein	NOUN
biomedich-176	290	31	expression	expression	NOUN
biomedich-176	290	32	.	.	PUNCT
biomedich-176	291	1	journal	journal	NOUN
biomedich-176	291	2	of	of	ADP
biomedich-176	291	3	thoracic	thoracic	NOUN
biomedich-176	291	4	oncology	oncology	NOUN
biomedich-176	291	5	,	,	PUNCT
biomedich-176	291	6	6(8	6(8	NUM
biomedich-176	291	7	)	)	PUNCT
biomedich-176	291	8	,	,	PUNCT
biomedich-176	291	9	1359	1359	NUM
biomedich-176	291	10	-	-	SYM
biomedich-176	291	11	1366	1366	NUM
biomedich-176	291	12	.	.	PUNCT
biomedich-176	292	1	lee	lee	PROPN
biomedich-176	292	2	,	,	PUNCT
biomedich-176	292	3	c.	c.	PROPN
biomedich-176	292	4	n.	n.	PROPN
biomedich-176	292	5	,	,	PUNCT
biomedich-176	292	6	lin	lin	PROPN
biomedich-176	292	7	,	,	PUNCT
biomedich-176	292	8	s.	s.	PROPN
biomedich-176	292	9	y.	y.	PROPN
biomedich-176	292	10	,	,	PUNCT
biomedich-176	292	11	lin	lin	PROPN
biomedich-176	292	12	,	,	PUNCT
biomedich-176	292	13	c.	c.	PROPN
biomedich-176	292	14	h.	h.	PROPN
biomedich-176	292	15	,	,	PUNCT
biomedich-176	292	16	shih	shih	PROPN
biomedich-176	292	17	,	,	PUNCT
biomedich-176	292	18	j.	j.	PROPN
biomedich-176	292	19	c.	c.	PROPN
biomedich-176	292	20	,	,	PUNCT
biomedich-176	292	21	lin	lin	PROPN
biomedich-176	292	22	,	,	PUNCT
biomedich-176	292	23	t.	t.	PROPN
biomedich-176	292	24	h.	h.	PROPN
biomedich-176	292	25	,	,	PUNCT
biomedich-176	292	26	&	&	CCONJ
biomedich-176	292	27	su	su	PROPN
biomedich-176	292	28	,	,	PUNCT
biomedich-176	292	29	y.	y.	PROPN
biomedich-176	292	30	n.	n.	PROPN
biomedich-176	292	31	(	(	PUNCT
biomedich-176	292	32	2012	2012	NUM
biomedich-176	292	33	)	)	PUNCT
biomedich-176	292	34	.	.	PUNCT
biomedich-176	293	1	clinical	clinical	ADJ
biomedich-176	293	2	utility	utility	NOUN
biomedich-176	293	3	of	of	ADP
biomedich-176	293	4	array	array	NOUN
biomedich-176	293	5	comparative	comparative	ADJ
biomedich-176	293	6	genomic	genomic	NOUN
biomedich-176	293	7	hybridization	hybridization	NOUN
biomedich-176	293	8	for	for	ADP
biomedich-176	293	9	prenatal	prenatal	ADJ
biomedich-176	293	10	diagnosis	diagnosis	NOUN
biomedich-176	293	11	:	:	PUNCT
biomedich-176	293	12	a	a	DET
biomedich-176	293	13	cohort	cohort	NOUN
biomedich-176	293	14	study	study	NOUN
biomedich-176	293	15	of	of	ADP
biomedich-176	293	16	3171	3171	NUM
biomedich-176	293	17	pregnancies	pregnancy	NOUN
biomedich-176	293	18	.	.	PUNCT
biomedich-176	294	1	bjog	bjog	NOUN
biomedich-176	294	2	:	:	PUNCT
biomedich-176	294	3	an	an	DET
biomedich-176	294	4	international	international	ADJ
biomedich-176	294	5	journal	journal	NOUN
biomedich-176	294	6	of	of	ADP
biomedich-176	294	7	obstetrics	obstetric	NOUN
biomedich-176	294	8	&	&	CCONJ
biomedich-176	294	9	gynaecology	gynaecology	NOUN
biomedich-176	294	10	,	,	PUNCT
biomedich-176	294	11	119(5	119(5	NUM
biomedich-176	294	12	)	)	PUNCT
biomedich-176	294	13	,	,	PUNCT
biomedich-176	294	14	614	614	NUM
biomedich-176	294	15	-	-	SYM
biomedich-176	294	16	625	625	NUM
biomedich-176	294	17	.	.	PUNCT
biomedich-176	295	1	les	le	NOUN
biomedich-176	295	2	,	,	PUNCT
biomedich-176	295	3	t.	t.	PROPN
biomedich-176	295	4	,	,	PUNCT
biomedich-176	295	5	markiewicz	markiewicz	NOUN
biomedich-176	295	6	,	,	PUNCT
biomedich-176	295	7	t.	t.	PROPN
biomedich-176	295	8	,	,	PUNCT
biomedich-176	295	9	osowski	osowski	PROPN
biomedich-176	295	10	,	,	PUNCT
biomedich-176	295	11	s.	s.	PROPN
biomedich-176	295	12	,	,	PUNCT
biomedich-176	295	13	cichowicz	cichowicz	NOUN
biomedich-176	295	14	,	,	PUNCT
biomedich-176	295	15	m.	m.	NOUN
biomedich-176	295	16	,	,	PUNCT
biomedich-176	295	17	&	&	CCONJ
biomedich-176	295	18	kozlowski	kozlowski	PROPN
biomedich-176	295	19	,	,	PUNCT
biomedich-176	295	20	w.	w.	PROPN
biomedich-176	295	21	(	(	PUNCT
biomedich-176	295	22	2014	2014	NUM
biomedich-176	295	23	,	,	PUNCT
biomedich-176	295	24	june	june	PROPN
biomedich-176	295	25	)	)	PUNCT
biomedich-176	295	26	.	.	PUNCT
biomedich-176	296	1	automatic	automatic	ADJ
biomedich-176	296	2	evaluation	evaluation	NOUN
biomedich-176	296	3	system	system	NOUN
biomedich-176	296	4	of	of	ADP
biomedich-176	296	5	fish	fish	NOUN
biomedich-176	296	6	images	image	NOUN
biomedich-176	296	7	in	in	ADP
biomedich-176	296	8	breast	breast	NOUN
biomedich-176	296	9	cancer	cancer	NOUN
biomedich-176	296	10	.	.	PUNCT
biomedich-176	297	1	in	in	ADP
biomedich-176	297	2	international	international	ADJ
biomedich-176	297	3	conference	conference	NOUN
biomedich-176	297	4	on	on	ADP
biomedich-176	297	5	image	image	NOUN
biomedich-176	297	6	and	and	CCONJ
biomedich-176	297	7	signal	signal	NOUN
biomedich-176	297	8	processing	processing	NOUN
biomedich-176	297	9	(	(	PUNCT
biomedich-176	297	10	pp	pp	ADJ
biomedich-176	297	11	.	.	PUNCT
biomedich-176	298	1	332	332	NUM
biomedich-176	298	2	-	-	SYM
biomedich-176	298	3	339	339	NUM
biomedich-176	298	4	)	)	PUNCT
biomedich-176	298	5	.	.	PUNCT
biomedich-176	299	1	springer	springer	NOUN
biomedich-176	299	2	,	,	PUNCT
biomedich-176	299	3	cham	cham	PROPN
biomedich-176	299	4	.	.	PUNCT
biomedich-176	300	1	li	li	PROPN
biomedich-176	300	2	,	,	PUNCT
biomedich-176	300	3	d.	d.	PROPN
biomedich-176	300	4	,	,	PUNCT
biomedich-176	300	5	wang	wang	PROPN
biomedich-176	300	6	,	,	PUNCT
biomedich-176	300	7	x.	x.	PROPN
biomedich-176	300	8	,	,	PUNCT
biomedich-176	300	9	lu	lu	PROPN
biomedich-176	300	10	,	,	PUNCT
biomedich-176	300	11	s.	s.	PROPN
biomedich-176	300	12	,	,	PUNCT
biomedich-176	300	13	wang	wang	PROPN
biomedich-176	300	14	,	,	PUNCT
biomedich-176	300	15	p.	p.	PROPN
biomedich-176	300	16	,	,	PUNCT
biomedich-176	300	17	wang	wang	PROPN
biomedich-176	300	18	,	,	PUNCT
biomedich-176	300	19	x.	x.	PROPN
biomedich-176	300	20	,	,	PUNCT
biomedich-176	300	21	yin	yin	PROPN
biomedich-176	300	22	,	,	PUNCT
biomedich-176	300	23	w.	w.	PROPN
biomedich-176	300	24	,	,	PUNCT
biomedich-176	300	25	...	...	PUNCT
biomedich-176	300	26	&	&	CCONJ
biomedich-176	300	27	li	li	PROPN
biomedich-176	300	28	,	,	PUNCT
biomedich-176	300	29	s.	s.	PROPN
biomedich-176	300	30	(	(	PUNCT
biomedich-176	300	31	2020	2020	NUM
biomedich-176	300	32	)	)	PUNCT
biomedich-176	300	33	.	.	PUNCT
biomedich-176	301	1	integrated	integrate	VERB
biomedich-176	301	2	analysis	analysis	NOUN
biomedich-176	301	3	revealing	reveal	VERB
biomedich-176	301	4	genome	genome	NOUN
biomedich-176	301	5	-	-	PUNCT
biomedich-176	301	6	wide	wide	ADJ
biomedich-176	301	7	chromosomal	chromosomal	ADJ
biomedich-176	301	8	copy	copy	NOUN
biomedich-176	301	9	number	number	NOUN
biomedich-176	301	10	variation	variation	NOUN
biomedich-176	301	11	in	in	ADP
biomedich-176	301	12	supraglottic	supraglottic	ADJ
biomedich-176	301	13	laryngeal	laryngeal	ADJ
biomedich-176	301	14	squamous	squamous	ADJ
biomedich-176	301	15	cell	cell	NOUN
biomedich-176	301	16	carcinoma	carcinoma	NOUN
biomedich-176	301	17	.	.	PUNCT
biomedich-176	302	1	oncology	oncology	NOUN
biomedich-176	302	2	letters	letter	NOUN
biomedich-176	302	3	,	,	PUNCT
biomedich-176	302	4	20(2	20(2	NUM
biomedich-176	302	5	)	)	PUNCT
biomedich-176	302	6	,	,	PUNCT
biomedich-176	302	7	12011212	12011212	NUM
biomedich-176	302	8	.	.	PUNCT
biomedich-176	303	1	lianidou	lianidou	NOUN
biomedich-176	303	2	,	,	PUNCT
biomedich-176	303	3	e.	e.	PROPN
biomedich-176	303	4	s.	s.	PROPN
biomedich-176	303	5	,	,	PUNCT
biomedich-176	303	6	&	&	CCONJ
biomedich-176	303	7	markou	markou	PROPN
biomedich-176	303	8	,	,	PUNCT
biomedich-176	303	9	a.	a.	NOUN
biomedich-176	303	10	(	(	PUNCT
biomedich-176	303	11	2011	2011	NUM
biomedich-176	303	12	)	)	PUNCT
biomedich-176	303	13	.	.	PUNCT
biomedich-176	304	1	circulating	circulate	VERB
biomedich-176	304	2	tumor	tumor	NOUN
biomedich-176	304	3	cells	cell	NOUN
biomedich-176	304	4	in	in	ADP
biomedich-176	304	5	breast	breast	NOUN
biomedich-176	304	6	cancer	cancer	NOUN
biomedich-176	304	7	:	:	PUNCT
biomedich-176	304	8	detection	detection	NOUN
biomedich-176	304	9	systems	system	NOUN
biomedich-176	304	10	,	,	PUNCT
biomedich-176	304	11	molecular	molecular	ADJ
biomedich-176	304	12	characterization	characterization	NOUN
biomedich-176	304	13	,	,	PUNCT
biomedich-176	304	14	and	and	CCONJ
biomedich-176	304	15	future	future	ADJ
biomedich-176	304	16	challenges	challenge	NOUN
biomedich-176	304	17	.	.	PUNCT
biomedich-176	305	1	clinical	clinical	ADJ
biomedich-176	305	2	chemistry	chemistry	NOUN
biomedich-176	305	3	,	,	PUNCT
biomedich-176	305	4	57(9	57(9	NOUN
biomedich-176	305	5	)	)	PUNCT
biomedich-176	305	6	,	,	PUNCT
biomedich-176	305	7	1242	1242	NUM
biomedich-176	305	8	-	-	SYM
biomedich-176	305	9	1255	1255	NUM
biomedich-176	305	10	.	.	PUNCT
biomedich-176	306	1	liehr	liehr	NOUN
biomedich-176	306	2	,	,	PUNCT
biomedich-176	306	3	t.	t.	PROPN
biomedich-176	306	4	,	,	PUNCT
biomedich-176	306	5	othman	othman	PROPN
biomedich-176	306	6	,	,	PUNCT
biomedich-176	306	7	m.	m.	NOUN
biomedich-176	306	8	a.	a.	PROPN
biomedich-176	306	9	,	,	PUNCT
biomedich-176	306	10	rittscher	rittscher	NOUN
biomedich-176	306	11	,	,	PUNCT
biomedich-176	306	12	k.	k.	PROPN
biomedich-176	306	13	,	,	PUNCT
biomedich-176	306	14	&	&	CCONJ
biomedich-176	306	15	alhourani	alhourani	PROPN
biomedich-176	306	16	,	,	PUNCT
biomedich-176	306	17	e.	e.	PROPN
biomedich-176	306	18	(	(	PUNCT
biomedich-176	306	19	2015	2015	NUM
biomedich-176	306	20	)	)	PUNCT
biomedich-176	306	21	.	.	PUNCT
biomedich-176	307	1	the	the	DET
biomedich-176	307	2	current	current	ADJ
biomedich-176	307	3	state	state	NOUN
biomedich-176	307	4	of	of	ADP
biomedich-176	307	5	molecular	molecular	ADJ
biomedich-176	307	6	cytogenetics	cytogenetic	NOUN
biomedich-176	307	7	in	in	ADP
biomedich-176	307	8	cancer	cancer	NOUN
biomedich-176	307	9	diagnosis	diagnosis	NOUN
biomedich-176	307	10	.	.	PUNCT
biomedich-176	308	1	expert	expert	NOUN
biomedich-176	308	2	review	review	NOUN
biomedich-176	308	3	of	of	ADP
biomedich-176	308	4	molecular	molecular	ADJ
biomedich-176	308	5	diagnostics	diagnostic	NOUN
biomedich-176	308	6	,	,	PUNCT
biomedich-176	308	7	15(4	15(4	NUM
biomedich-176	308	8	)	)	PUNCT
biomedich-176	308	9	,	,	PUNCT
biomedich-176	308	10	517526	517526	NUM
biomedich-176	308	11	.	.	PUNCT
biomedich-176	309	1	lima	lima	PROPN
biomedich-176	309	2	,	,	PUNCT
biomedich-176	309	3	j.	j.	PROPN
biomedich-176	309	4	f.	f.	PROPN
biomedich-176	309	5	,	,	PUNCT
biomedich-176	309	6	maia	maia	PROPN
biomedich-176	309	7	,	,	PUNCT
biomedich-176	309	8	p.	p.	PROPN
biomedich-176	309	9	,	,	PUNCT
biomedich-176	309	10	t.	t.	PROPN
biomedich-176	309	11	magalhães	magalhães	PROPN
biomedich-176	309	12	,	,	PUNCT
biomedich-176	309	13	b.	b.	PROPN
biomedich-176	309	14	,	,	PUNCT
biomedich-176	309	15	cerqueira	cerqueira	PROPN
biomedich-176	309	16	,	,	PUNCT
biomedich-176	309	17	l.	l.	PROPN
biomedich-176	309	18	,	,	PUNCT
biomedich-176	309	19	&	&	CCONJ
biomedich-176	309	20	azevedo	azevedo	PROPN
biomedich-176	309	21	,	,	PUNCT
biomedich-176	309	22	n.	n.	PROPN
biomedich-176	309	23	f.	f.	PROPN
biomedich-176	309	24	(	(	PUNCT
biomedich-176	309	25	2020	2020	NUM
biomedich-176	309	26	)	)	PUNCT
biomedich-176	309	27	.	.	PUNCT
biomedich-176	310	1	a	a	DET
biomedich-176	310	2	comprehensive	comprehensive	ADJ
biomedich-176	310	3	model	model	NOUN
biomedich-176	310	4	for	for	ADP
biomedich-176	310	5	the	the	DET
biomedich-176	310	6	diffusion	diffusion	NOUN
biomedich-176	310	7	and	and	CCONJ
biomedich-176	310	8	hybridization	hybridization	NOUN
biomedich-176	310	9	processes	process	NOUN
biomedich-176	310	10	of	of	ADP
biomedich-176	310	11	nucleic	nucleic	ADJ
biomedich-176	310	12	acid	acid	NOUN
biomedich-176	310	13	probes	probe	NOUN
biomedich-176	310	14	in	in	ADP
biomedich-176	310	15	fluorescence	fluorescence	NOUN
biomedich-176	310	16	in	in	ADP
biomedich-176	310	17	situ	situ	ADJ
biomedich-176	310	18	hybridization	hybridization	NOUN
biomedich-176	310	19	.	.	PUNCT
biomedich-176	311	1	biotechnology	biotechnology	NOUN
biomedich-176	311	2	and	and	CCONJ
biomedich-176	311	3	bioengineering	bioengineering	NOUN
biomedich-176	311	4	,	,	PUNCT
biomedich-176	311	5	117(10	117(10	NUM
biomedich-176	311	6	)	)	PUNCT
biomedich-176	311	7	,	,	PUNCT
biomedich-176	311	8	3212	3212	NUM
biomedich-176	311	9	-	-	SYM
biomedich-176	311	10	3223	3223	NUM
biomedich-176	311	11	.	.	PUNCT
biomedich-176	312	1	mcneil	mcneil	PROPN
biomedich-176	312	2	,	,	PUNCT
biomedich-176	312	3	n.	n.	PROPN
biomedich-176	312	4	,	,	PUNCT
biomedich-176	312	5	&	&	CCONJ
biomedich-176	312	6	ried	rie	VERB
biomedich-176	312	7	,	,	PUNCT
biomedich-176	312	8	t.	t.	PROPN
biomedich-176	312	9	(	(	PUNCT
biomedich-176	312	10	2000	2000	NUM
biomedich-176	312	11	)	)	PUNCT
biomedich-176	312	12	.	.	PUNCT
biomedich-176	313	1	novel	novel	ADJ
biomedich-176	313	2	molecular	molecular	ADJ
biomedich-176	313	3	cytogenetic	cytogenetic	ADJ
biomedich-176	313	4	techniques	technique	NOUN
biomedich-176	313	5	for	for	ADP
biomedich-176	313	6	identifying	identify	VERB
biomedich-176	313	7	complex	complex	ADJ
biomedich-176	313	8	chromosomal	chromosomal	ADJ
biomedich-176	313	9	rearrangements	rearrangement	NOUN
biomedich-176	313	10	:	:	PUNCT
biomedich-176	313	11	technology	technology	NOUN
biomedich-176	313	12	and	and	CCONJ
biomedich-176	313	13	applications	application	NOUN
biomedich-176	313	14	in	in	ADP
biomedich-176	313	15	molecular	molecular	ADJ
biomedich-176	313	16	medicine	medicine	NOUN
biomedich-176	313	17	.	.	PUNCT
biomedich-176	314	1	expert	expert	ADJ
biomedich-176	314	2	reviews	review	NOUN
biomedich-176	314	3	in	in	ADP
biomedich-176	314	4	molecular	molecular	ADJ
biomedich-176	314	5	medicine	medicine	NOUN
biomedich-176	314	6	,	,	PUNCT
biomedich-176	314	7	2000	2000	NUM
biomedich-176	314	8	,	,	PUNCT
biomedich-176	314	9	1–14	1–14	PROPN
biomedich-176	314	10	.	.	PUNCT
biomedich-176	314	11	mego	mego	PROPN
biomedich-176	314	12	,	,	PUNCT
biomedich-176	314	13	m.	m.	NOUN
biomedich-176	314	14	,	,	PUNCT
biomedich-176	314	15	mani	mani	PROPN
biomedich-176	314	16	,	,	PUNCT
biomedich-176	314	17	s.	s.	PROPN
biomedich-176	314	18	a.	a.	PROPN
biomedich-176	314	19	,	,	PUNCT
biomedich-176	314	20	&	&	CCONJ
biomedich-176	314	21	cristofanilli	cristofanilli	PROPN
biomedich-176	314	22	,	,	PUNCT
biomedich-176	314	23	m.	m.	NOUN
biomedich-176	314	24	(	(	PUNCT
biomedich-176	314	25	2010	2010	NUM
biomedich-176	314	26	)	)	PUNCT
biomedich-176	314	27	.	.	PUNCT
biomedich-176	315	1	molecular	molecular	ADJ
biomedich-176	315	2	mechanisms	mechanism	NOUN
biomedich-176	315	3	of	of	ADP
biomedich-176	315	4	metastasis	metastasis	NOUN
biomedich-176	315	5	in	in	ADP
biomedich-176	315	6	breast	breast	NOUN
biomedich-176	315	7	cancer	cancer	NOUN
biomedich-176	315	8	—	—	PUNCT
biomedich-176	315	9	clinical	clinical	ADJ
biomedich-176	315	10	applications	application	NOUN
biomedich-176	315	11	.	.	PUNCT
biomedich-176	316	1	nature	nature	NOUN
biomedich-176	316	2	reviews	review	VERB
biomedich-176	316	3	clinical	clinical	ADJ
biomedich-176	316	4	oncology	oncology	NOUN
biomedich-176	316	5	,	,	PUNCT
biomedich-176	316	6	7(12	7(12	NUM
biomedich-176	316	7	)	)	PUNCT
biomedich-176	316	8	,	,	PUNCT
biomedich-176	316	9	693701	693701	NUM
biomedich-176	316	10	.	.	PUNCT
biomedich-176	317	1	moter	moter	PROPN
biomedich-176	317	2	,	,	PUNCT
biomedich-176	317	3	a.	a.	PROPN
biomedich-176	317	4	,	,	PUNCT
biomedich-176	317	5	&	&	CCONJ
biomedich-176	317	6	göbel	göbel	PROPN
biomedich-176	317	7	,	,	PUNCT
biomedich-176	317	8	u.	u.	PROPN
biomedich-176	317	9	b.	b.	PROPN
biomedich-176	317	10	(	(	PUNCT
biomedich-176	317	11	2000	2000	NUM
biomedich-176	317	12	)	)	PUNCT
biomedich-176	317	13	.	.	PUNCT
biomedich-176	318	1	fluorescence	fluorescence	NOUN
biomedich-176	318	2	in	in	ADP
biomedich-176	318	3	situ	situ	ADJ
biomedich-176	318	4	hybridization	hybridization	NOUN
biomedich-176	318	5	(	(	PUNCT
biomedich-176	318	6	fish	fish	NOUN
biomedich-176	318	7	)	)	PUNCT
biomedich-176	318	8	for	for	ADP
biomedich-176	318	9	direct	direct	ADJ
biomedich-176	318	10	visualization	visualization	NOUN
biomedich-176	318	11	of	of	ADP
biomedich-176	318	12	microorganisms	microorganism	NOUN
biomedich-176	318	13	.	.	PUNCT
biomedich-176	319	1	munné	munné	NOUN
biomedich-176	319	2	,	,	PUNCT
biomedich-176	319	3	s.	s.	PROPN
biomedich-176	319	4	(	(	PUNCT
biomedich-176	319	5	2012	2012	NUM
biomedich-176	319	6	)	)	PUNCT
biomedich-176	319	7	.	.	PUNCT
biomedich-176	320	1	preimplantation	preimplantation	NOUN
biomedich-176	320	2	genetic	genetic	ADJ
biomedich-176	320	3	diagnosis	diagnosis	NOUN
biomedich-176	320	4	for	for	ADP
biomedich-176	320	5	aneuploidy	aneuploidy	ADJ
biomedich-176	320	6	and	and	CCONJ
biomedich-176	320	7	translocations	translocation	NOUN
biomedich-176	320	8	using	use	VERB
biomedich-176	320	9	array	array	NOUN
biomedich-176	320	10	comparative	comparative	ADJ
biomedich-176	320	11	genomic	genomic	NOUN
biomedich-176	320	12	hybridization	hybridization	NOUN
biomedich-176	320	13	.	.	PUNCT
biomedich-176	321	1	current	current	ADJ
biomedich-176	321	2	genomics	genomic	NOUN
biomedich-176	321	3	,	,	PUNCT
biomedich-176	321	4	13(6	13(6	PROPN
biomedich-176	321	5	)	)	PUNCT
biomedich-176	321	6	,	,	PUNCT
biomedich-176	321	7	463	463	NUM
biomedich-176	321	8	-	-	SYM
biomedich-176	321	9	470	470	NUM
biomedich-176	321	10	.	.	PUNCT
biomedich-176	322	1	nguyen	nguyen	PROPN
biomedich-176	322	2	,	,	PUNCT
biomedich-176	322	3	h.	h.	PROPN
biomedich-176	322	4	t.	t.	PROPN
biomedich-176	322	5	,	,	PUNCT
biomedich-176	322	6	dupont	dupont	PROPN
biomedich-176	322	7	,	,	PUNCT
biomedich-176	322	8	l.	l.	PROPN
biomedich-176	322	9	n.	n.	PROPN
biomedich-176	322	10	,	,	PUNCT
biomedich-176	322	11	cuttaz	cuttaz	PROPN
biomedich-176	322	12	,	,	PUNCT
biomedich-176	322	13	e.	e.	PROPN
biomedich-176	322	14	a.	a.	PROPN
biomedich-176	322	15	,	,	PUNCT
biomedich-176	322	16	jean	jean	PROPN
biomedich-176	322	17	,	,	PUNCT
biomedich-176	322	18	a.	a.	NOUN
biomedich-176	322	19	m.	m.	NOUN
biomedich-176	322	20	,	,	PUNCT
biomedich-176	322	21	trouillon	trouillon	PROPN
biomedich-176	322	22	,	,	PUNCT
biomedich-176	322	23	r.	r.	PROPN
biomedich-176	322	24	,	,	PUNCT
biomedich-176	322	25	&	&	CCONJ
biomedich-176	322	26	gijs	gijs	PROPN
biomedich-176	322	27	,	,	PUNCT
biomedich-176	322	28	m.	m.	NOUN
biomedich-176	322	29	a.	a.	NOUN
biomedich-176	322	30	(	(	PUNCT
biomedich-176	322	31	2018	2018	NUM
biomedich-176	322	32	)	)	PUNCT
biomedich-176	322	33	.	.	PUNCT
biomedich-176	323	1	breast	breast	NOUN
biomedich-176	323	2	cancer	cancer	NOUN
biomedich-176	323	3	her2	her2	VERB
biomedich-176	323	4	analysis	analysis	NOUN
biomedich-176	323	5	by	by	ADP
biomedich-176	323	6	extra	extra	ADJ
biomedich-176	323	7	-	-	ADJ
biomedich-176	323	8	short	short	ADJ
biomedich-176	323	9	incubation	incubation	NOUN
biomedich-176	323	10	microfluidics	microfluidic	NOUN
biomedich-176	323	11	-	-	PUNCT
biomedich-176	323	12	assisted	assist	VERB
biomedich-176	323	13	fluorescence	fluorescence	NOUN
biomedich-176	323	14	in	in	ADP
biomedich-176	323	15	situ	situ	ADJ
biomedich-176	323	16	hybridization	hybridization	NOUN
biomedich-176	323	17	(	(	PUNCT
biomedich-176	323	18	esima	esima	PROPN
biomedich-176	323	19	fish	fish	PROPN
biomedich-176	323	20	)	)	PUNCT
biomedich-176	323	21	.	.	PUNCT
biomedich-176	324	1	microelectronic	microelectronic	ADJ
biomedich-176	324	2	engineering	engineering	NOUN
biomedich-176	324	3	,	,	PUNCT
biomedich-176	324	4	189	189	NUM
biomedich-176	324	5	,	,	PUNCT
biomedich-176	324	6	33	33	NUM
biomedich-176	324	7	-	-	SYM
biomedich-176	324	8	38	38	NUM
biomedich-176	324	9	.	.	PUNCT
biomedich-176	325	1	ormandy	ormandy	PROPN
biomedich-176	325	2	,	,	PUNCT
biomedich-176	325	3	c.	c.	PROPN
biomedich-176	325	4	j.	j.	PROPN
biomedich-176	325	5	,	,	PUNCT
biomedich-176	325	6	musgrove	musgrove	PROPN
biomedich-176	325	7	,	,	PUNCT
biomedich-176	325	8	e.	e.	PROPN
biomedich-176	325	9	a.	a.	PROPN
biomedich-176	325	10	,	,	PUNCT
biomedich-176	325	11	hui	hui	PROPN
biomedich-176	325	12	,	,	PUNCT
biomedich-176	325	13	r.	r.	PROPN
biomedich-176	325	14	,	,	PUNCT
biomedich-176	325	15	daly	daly	PROPN
biomedich-176	325	16	,	,	PUNCT
biomedich-176	325	17	r.	r.	PROPN
biomedich-176	325	18	j.	j.	PROPN
biomedich-176	325	19	,	,	PUNCT
biomedich-176	325	20	&	&	CCONJ
biomedich-176	325	21	sutherland	sutherland	PROPN
biomedich-176	325	22	,	,	PUNCT
biomedich-176	325	23	r.	r.	PROPN
biomedich-176	325	24	l.	l.	PROPN
biomedich-176	325	25	(	(	PUNCT
biomedich-176	325	26	2003	2003	NUM
biomedich-176	325	27	)	)	PUNCT
biomedich-176	325	28	.	.	PUNCT
biomedich-176	326	1	cyclin	cyclin	NOUN
biomedich-176	326	2	d1	d1	PROPN
biomedich-176	326	3	,	,	PUNCT
biomedich-176	326	4	ems1	ems1	NOUN
biomedich-176	326	5	and	and	CCONJ
biomedich-176	326	6	11q13	11q13	NUM
biomedich-176	326	7	amplification	amplification	NOUN
biomedich-176	326	8	in	in	ADP
biomedich-176	326	9	breast	breast	NOUN
biomedich-176	326	10	cancer	cancer	NOUN
biomedich-176	326	11	.	.	PUNCT
biomedich-176	327	1	breast	breast	NOUN
biomedich-176	327	2	cancer	cancer	NOUN
biomedich-176	327	3	research	research	NOUN
biomedich-176	327	4	and	and	CCONJ
biomedich-176	327	5	treatment	treatment	NOUN
biomedich-176	327	6	,	,	PUNCT
biomedich-176	327	7	78(3	78(3	NOUN
biomedich-176	327	8	)	)	PUNCT
biomedich-176	327	9	,	,	PUNCT
biomedich-176	327	10	323	323	NUM
biomedich-176	327	11	-	-	SYM
biomedich-176	327	12	335	335	NUM
biomedich-176	327	13	.	.	PUNCT
biomedich-176	328	1	pandis	pandi	NOUN
biomedich-176	328	2	,	,	PUNCT
biomedich-176	328	3	n.	n.	PROPN
biomedich-176	328	4	,	,	PUNCT
biomedich-176	328	5	heim	heim	PROPN
biomedich-176	328	6	,	,	PUNCT
biomedich-176	328	7	s.	s.	PROPN
biomedich-176	328	8	,	,	PUNCT
biomedich-176	328	9	bardi	bardi	PROPN
biomedich-176	328	10	,	,	PUNCT
biomedich-176	328	11	g.	g.	PROPN
biomedich-176	328	12	,	,	PUNCT
biomedich-176	328	13	idvall	idvall	PROPN
biomedich-176	328	14	,	,	PUNCT
biomedich-176	328	15	i.	i.	NOUN
biomedich-176	328	16	,	,	PUNCT
biomedich-176	328	17	mandahl	mandahl	NOUN
biomedich-176	328	18	,	,	PUNCT
biomedich-176	328	19	n.	n.	NOUN
biomedich-176	328	20	,	,	PUNCT
biomedich-176	328	21	&	&	CCONJ
biomedich-176	328	22	mitelman	mitelman	PROPN
biomedich-176	328	23	,	,	PUNCT
biomedich-176	328	24	f.	f.	PROPN
biomedich-176	328	25	(	(	PUNCT
biomedich-176	328	26	1992	1992	NUM
biomedich-176	328	27	)	)	PUNCT
biomedich-176	328	28	.	.	PUNCT
biomedich-176	329	1	whole‐arm	whole‐arm	PROPN
biomedich-176	329	2	t	t	PROPN
biomedich-176	329	3	(	(	PUNCT
biomedich-176	329	4	1	1	NUM
biomedich-176	329	5	;	;	PUNCT
biomedich-176	329	6	16	16	NUM
biomedich-176	329	7	)	)	PUNCT
biomedich-176	329	8	and	and	CCONJ
biomedich-176	329	9	i	i	PRON
biomedich-176	329	10	(	(	PUNCT
biomedich-176	329	11	1q	1q	NUM
biomedich-176	329	12	)	)	PUNCT
biomedich-176	329	13	as	as	SCONJ
biomedich-176	329	14	sole	sole	ADJ
biomedich-176	329	15	anomalies	anomaly	NOUN
biomedich-176	329	16	identify	identify	VERB
biomedich-176	329	17	gain	gain	NOUN
biomedich-176	329	18	of	of	ADP
biomedich-176	329	19	1	1	NUM
biomedich-176	329	20	q	q	NOUN
biomedich-176	329	21	as	as	ADP
biomedich-176	329	22	a	a	DET
biomedich-176	329	23	primary	primary	ADJ
biomedich-176	329	24	chromosomal	chromosomal	ADJ
biomedich-176	329	25	abnormality	abnormality	NOUN
biomedich-176	329	26	in	in	ADP
biomedich-176	329	27	breast	breast	NOUN
biomedich-176	329	28	cancer	cancer	NOUN
biomedich-176	329	29	.	.	PUNCT
biomedich-176	330	1	genes	gene	NOUN
biomedich-176	330	2	,	,	PUNCT
biomedich-176	330	3	chromosomes	chromosome	NOUN
biomedich-176	330	4	and	and	CCONJ
biomedich-176	330	5	cancer	cancer	NOUN
biomedich-176	330	6	,	,	PUNCT
biomedich-176	330	7	5(3	5(3	NUM
biomedich-176	330	8	)	)	PUNCT
biomedich-176	330	9	,	,	PUNCT
biomedich-176	330	10	235	235	NUM
biomedich-176	330	11	-	-	SYM
biomedich-176	330	12	238	238	NUM
biomedich-176	330	13	.	.	PUNCT
biomedich-176	330	14	pinkel	pinkel	PROPN
biomedich-176	330	15	,	,	PUNCT
biomedich-176	330	16	d.	d.	PROPN
biomedich-176	330	17	,	,	PUNCT
biomedich-176	330	18	gray	gray	ADJ
biomedich-176	330	19	,	,	PUNCT
biomedich-176	330	20	j.	j.	PROPN
biomedich-176	330	21	w.	w.	PROPN
biomedich-176	330	22	,	,	PUNCT
biomedich-176	330	23	kallioniemi	kallioniemi	PROPN
biomedich-176	330	24	,	,	PUNCT
biomedich-176	330	25	a.	a.	PROPN
biomedich-176	330	26	,	,	PUNCT
biomedich-176	330	27	kallioniemi	kallioniemi	PROPN
biomedich-176	330	28	,	,	PUNCT
biomedich-176	330	29	o.	o.	PROPN
biomedich-176	330	30	p.	p.	PROPN
biomedich-176	330	31	,	,	PUNCT
biomedich-176	330	32	waldman	waldman	PROPN
biomedich-176	330	33	,	,	PUNCT
biomedich-176	330	34	f.	f.	PROPN
biomedich-176	330	35	,	,	PUNCT
biomedich-176	330	36	&	&	CCONJ
biomedich-176	330	37	sakamoto	sakamoto	PROPN
biomedich-176	330	38	,	,	PUNCT
biomedich-176	330	39	m.	m.	NOUN
biomedich-176	330	40	(	(	PUNCT
biomedich-176	330	41	2011	2011	NUM
biomedich-176	330	42	)	)	PUNCT
biomedich-176	330	43	.	.	PUNCT
biomedich-176	331	1	u.s	u.s	PROPN
biomedich-176	331	2	.	.	PROPN
biomedich-176	331	3	patent	patent	NOUN
biomedich-176	331	4	no	no	PROPN
biomedich-176	331	5	.	.	PUNCT
biomedich-176	332	1	8,021,837	8,021,837	NUM
biomedich-176	332	2	.	.	PUNCT
biomedich-176	333	1	washington	washington	PROPN
biomedich-176	333	2	,	,	PUNCT
biomedich-176	333	3	dc	dc	PROPN
biomedich-176	333	4	:	:	PUNCT
biomedich-176	333	5	u.s	u.s	PROPN
biomedich-176	333	6	.	.	PROPN
biomedich-176	333	7	patent	patent	NOUN
biomedich-176	333	8	and	and	CCONJ
biomedich-176	333	9	trademark	trademark	NOUN
biomedich-176	333	10	office	office	NOUN
biomedich-176	333	11	.	.	PUNCT
biomedich-176	334	1	prat	prat	PROPN
biomedich-176	334	2	,	,	PUNCT
biomedich-176	334	3	a.	a.	NOUN
biomedich-176	334	4	,	,	PUNCT
biomedich-176	334	5	&	&	CCONJ
biomedich-176	334	6	perou	perou	PROPN
biomedich-176	334	7	,	,	PUNCT
biomedich-176	334	8	c.	c.	PROPN
biomedich-176	334	9	m.	m.	NOUN
biomedich-176	334	10	(	(	PUNCT
biomedich-176	334	11	2011	2011	NUM
biomedich-176	334	12	)	)	PUNCT
biomedich-176	334	13	.	.	PUNCT
biomedich-176	335	1	deconstructing	deconstruct	VERB
biomedich-176	335	2	the	the	DET
biomedich-176	335	3	molecular	molecular	ADJ
biomedich-176	335	4	portraits	portrait	NOUN
biomedich-176	335	5	of	of	ADP
biomedich-176	335	6	breast	breast	NOUN
biomedich-176	335	7	cancer	cancer	NOUN
biomedich-176	335	8	.	.	PUNCT
biomedich-176	336	1	molecular	molecular	ADJ
biomedich-176	336	2	oncology	oncology	NOUN
biomedich-176	336	3	,	,	PUNCT
biomedich-176	336	4	5(1	5(1	NUM
biomedich-176	336	5	)	)	PUNCT
biomedich-176	336	6	,	,	PUNCT
biomedich-176	336	7	5	5	NUM
biomedich-176	336	8	-	-	SYM
biomedich-176	336	9	23	23	NUM
biomedich-176	336	10	.	.	PUNCT
biomedich-176	337	1	prat	prat	PROPN
biomedich-176	337	2	,	,	PUNCT
biomedich-176	337	3	a.	a.	PROPN
biomedich-176	337	4	,	,	PUNCT
biomedich-176	337	5	adamo	adamo	PROPN
biomedich-176	337	6	,	,	PUNCT
biomedich-176	337	7	b.	b.	PROPN
biomedich-176	337	8	,	,	PUNCT
biomedich-176	337	9	cheang	cheang	PROPN
biomedich-176	337	10	,	,	PUNCT
biomedich-176	337	11	m.	m.	PROPN
biomedich-176	337	12	c.	c.	PROPN
biomedich-176	337	13	,	,	PUNCT
biomedich-176	337	14	anders	ander	NOUN
biomedich-176	337	15	,	,	PUNCT
biomedich-176	337	16	c.	c.	PROPN
biomedich-176	337	17	k.	k.	PROPN
biomedich-176	337	18	,	,	PUNCT
biomedich-176	337	19	carey	carey	PROPN
biomedich-176	337	20	,	,	PUNCT
biomedich-176	337	21	l.	l.	PROPN
biomedich-176	337	22	a.	a.	PROPN
biomedich-176	337	23	,	,	PUNCT
biomedich-176	337	24	&	&	CCONJ
biomedich-176	337	25	perou	perou	PROPN
biomedich-176	337	26	,	,	PUNCT
biomedich-176	337	27	c.	c.	PROPN
biomedich-176	337	28	m.	m.	NOUN
biomedich-176	337	29	(	(	PUNCT
biomedich-176	337	30	2013	2013	NUM
biomedich-176	337	31	)	)	PUNCT
biomedich-176	337	32	.	.	PUNCT
biomedich-176	338	1	molecular	molecular	ADJ
biomedich-176	338	2	characterization	characterization	NOUN
biomedich-176	338	3	of	of	ADP
biomedich-176	338	4	basallike	basallike	ADP
biomedich-176	338	5	and	and	CCONJ
biomedich-176	338	6	non	non	ADJ
biomedich-176	338	7	-	-	ADJ
biomedich-176	338	8	basal	basal	ADJ
biomedich-176	338	9	-	-	PUNCT
biomedich-176	338	10	like	like	ADJ
biomedich-176	338	11	triple	triple	ADJ
biomedich-176	338	12	-	-	PUNCT
biomedich-176	338	13	negative	negative	ADJ
biomedich-176	338	14	breast	breast	NOUN
biomedich-176	338	15	cancer	cancer	NOUN
biomedich-176	338	16	.	.	PUNCT
biomedich-176	339	1	the	the	DET
biomedich-176	339	2	oncologist	oncologist	NOUN
biomedich-176	339	3	,	,	PUNCT
biomedich-176	339	4	18(2	18(2	NUM
biomedich-176	339	5	)	)	PUNCT
biomedich-176	339	6	,	,	PUNCT
biomedich-176	339	7	123	123	NUM
biomedich-176	339	8	.	.	PUNCT
biomedich-176	339	9	prat	prat	PROPN
biomedich-176	339	10	,	,	PUNCT
biomedich-176	339	11	a.	a.	PROPN
biomedich-176	339	12	,	,	PUNCT
biomedich-176	339	13	parker	parker	PROPN
biomedich-176	339	14	,	,	PUNCT
biomedich-176	339	15	j.	j.	PROPN
biomedich-176	339	16	s.	s.	PROPN
biomedich-176	339	17	,	,	PUNCT
biomedich-176	339	18	karginova	karginova	PROPN
biomedich-176	339	19	,	,	PUNCT
biomedich-176	339	20	o.	o.	PROPN
biomedich-176	339	21	,	,	PUNCT
biomedich-176	339	22	fan	fan	PROPN
biomedich-176	339	23	,	,	PUNCT
biomedich-176	339	24	c.	c.	PROPN
biomedich-176	339	25	,	,	PUNCT
biomedich-176	339	26	livasy	livasy	PROPN
biomedich-176	339	27	,	,	PUNCT
biomedich-176	339	28	c.	c.	PROPN
biomedich-176	339	29	,	,	PUNCT
biomedich-176	339	30	herschkowitz	herschkowitz	PROPN
biomedich-176	339	31	,	,	PUNCT
biomedich-176	339	32	j.	j.	PROPN
biomedich-176	339	33	i.	i.	PROPN
biomedich-176	339	34	,	,	PUNCT
biomedich-176	339	35	...	...	PUNCT
biomedich-176	339	36	&	&	CCONJ
biomedich-176	339	37	perou	perou	PROPN
biomedich-176	339	38	,	,	PUNCT
biomedich-176	339	39	c.	c.	PROPN
biomedich-176	339	40	m.	m.	NOUN
biomedich-176	339	41	(	(	PUNCT
biomedich-176	339	42	2010	2010	NUM
biomedich-176	339	43	)	)	PUNCT
biomedich-176	339	44	.	.	PUNCT
biomedich-176	340	1	phenotypic	phenotypic	ADJ
biomedich-176	340	2	and	and	CCONJ
biomedich-176	340	3	molecular	molecular	ADJ
biomedich-176	340	4	characterization	characterization	NOUN
biomedich-176	340	5	of	of	ADP
biomedich-176	340	6	the	the	DET
biomedich-176	340	7	claudin	claudin	VERB
biomedich-176	340	8	-	-	PUNCT
biomedich-176	340	9	low	low	ADJ
biomedich-176	340	10	intrinsic	intrinsic	ADJ
biomedich-176	340	11	subtype	subtype	NOUN
biomedich-176	340	12	of	of	ADP
biomedich-176	340	13	breast	breast	NOUN
biomedich-176	340	14	cancer	cancer	NOUN
biomedich-176	340	15	.	.	PUNCT
biomedich-176	341	1	breast	breast	NOUN
biomedich-176	341	2	cancer	cancer	NOUN
biomedich-176	341	3	research	research	NOUN
biomedich-176	341	4	,	,	PUNCT
biomedich-176	341	5	12(5	12(5	NUM
biomedich-176	341	6	)	)	PUNCT
biomedich-176	341	7	,	,	PUNCT
biomedich-176	341	8	r68	r68	NOUN
biomedich-176	341	9	.	.	PUNCT
biomedich-176	342	1	price	price	NOUN
biomedich-176	342	2	,	,	PUNCT
biomedich-176	342	3	c.	c.	PROPN
biomedich-176	342	4	m.	m.	NOUN
biomedich-176	342	5	(	(	PUNCT
biomedich-176	342	6	1993	1993	NUM
biomedich-176	342	7	)	)	PUNCT
biomedich-176	342	8	.	.	PUNCT
biomedich-176	343	1	fluorescence	fluorescence	NOUN
biomedich-176	343	2	in	in	ADP
biomedich-176	343	3	situ	situ	ADJ
biomedich-176	343	4	hybridization	hybridization	NOUN
biomedich-176	343	5	.	.	PUNCT
biomedich-176	344	1	blood	blood	NOUN
biomedich-176	344	2	reviews	review	NOUN
biomedich-176	344	3	,	,	PUNCT
biomedich-176	344	4	7(2	7(2	NUM
biomedich-176	344	5	)	)	PUNCT
biomedich-176	344	6	,	,	PUNCT
biomedich-176	344	7	127	127	NUM
biomedich-176	344	8	-	-	SYM
biomedich-176	344	9	134	134	NUM
biomedich-176	344	10	.	.	PUNCT
biomedich-176	345	1	przybytkowski	przybytkowski	PROPN
biomedich-176	345	2	,	,	PUNCT
biomedich-176	345	3	e.	e.	PROPN
biomedich-176	345	4	,	,	PUNCT
biomedich-176	345	5	lenkiewicz	lenkiewicz	PROPN
biomedich-176	345	6	,	,	PUNCT
biomedich-176	345	7	e.	e.	PROPN
biomedich-176	345	8	,	,	PUNCT
biomedich-176	345	9	barrett	barrett	PROPN
biomedich-176	345	10	,	,	PUNCT
biomedich-176	345	11	m.	m.	PROPN
biomedich-176	345	12	t.	t.	PROPN
biomedich-176	345	13	,	,	PUNCT
biomedich-176	345	14	klein	klein	PROPN
biomedich-176	345	15	,	,	PUNCT
biomedich-176	345	16	k.	k.	PROPN
biomedich-176	345	17	,	,	PUNCT
biomedich-176	345	18	nabavi	nabavi	PROPN
biomedich-176	345	19	,	,	PUNCT
biomedich-176	345	20	s.	s.	PROPN
biomedich-176	345	21	,	,	PUNCT
biomedich-176	345	22	greenwood	greenwood	PROPN
biomedich-176	345	23	,	,	PUNCT
biomedich-176	345	24	c.	c.	PROPN
biomedich-176	345	25	m.	m.	PROPN
biomedich-176	345	26	,	,	PUNCT
biomedich-176	345	27	&	&	CCONJ
biomedich-176	345	28	basik	basik	PROPN
biomedich-176	345	29	,	,	PUNCT
biomedich-176	345	30	m.	m.	NOUN
biomedich-176	345	31	(	(	PUNCT
biomedich-176	345	32	2014	2014	NUM
biomedich-176	345	33	)	)	PUNCT
biomedich-176	345	34	.	.	PUNCT
biomedich-176	346	1	chromosome	chromosome	NOUN
biomedich-176	346	2	-	-	PUNCT
biomedich-176	346	3	breakage	breakage	NOUN
biomedich-176	346	4	genomic	genomic	NOUN
biomedich-176	346	5	instability	instability	NOUN
biomedich-176	346	6	and	and	CCONJ
biomedich-176	346	7	chromothripsis	chromothripsis	NOUN
biomedich-176	346	8	in	in	ADP
biomedich-176	346	9	breast	breast	NOUN
biomedich-176	346	10	cancer	cancer	NOUN
biomedich-176	346	11	.	.	PUNCT
biomedich-176	347	1	bmc	bmc	ADJ
biomedich-176	347	2	genomics	genomic	NOUN
biomedich-176	347	3	,	,	PUNCT
biomedich-176	347	4	15(1	15(1	NUM
biomedich-176	347	5	)	)	PUNCT
biomedich-176	347	6	,	,	PUNCT
biomedich-176	347	7	579	579	NUM
biomedich-176	347	8	.	.	PUNCT
biomedich-176	348	1	qaisar	qaisar	PROPN
biomedich-176	348	2	,	,	PUNCT
biomedich-176	348	3	u.	u.	PROPN
biomedich-176	348	4	,	,	PUNCT
biomedich-176	348	5	tayyeb	tayyeb	PROPN
biomedich-176	348	6	,	,	PUNCT
biomedich-176	348	7	a.	a.	NOUN
biomedich-176	348	8	,	,	PUNCT
biomedich-176	348	9	&	&	CCONJ
biomedich-176	348	10	bhat	bhat	PROPN
biomedich-176	348	11	,	,	PUNCT
biomedich-176	348	12	t.	t.	NOUN
biomedich-176	348	13	a.	a.	NOUN
biomedich-176	348	14	(	(	PUNCT
biomedich-176	348	15	2017	2017	NUM
biomedich-176	348	16	)	)	PUNCT
biomedich-176	348	17	.	.	PUNCT
biomedich-176	349	1	techniques	technique	NOUN
biomedich-176	349	2	of	of	ADP
biomedich-176	349	3	chromosomal	chromosomal	ADJ
biomedich-176	349	4	studies	study	NOUN
biomedich-176	349	5	.	.	PUNCT
biomedich-176	350	1	in	in	ADP
biomedich-176	350	2	chromosome	chromosome	NOUN
biomedich-176	350	3	structure	structure	NOUN
biomedich-176	350	4	and	and	CCONJ
biomedich-176	350	5	aberrations	aberration	NOUN
biomedich-176	350	6	(	(	PUNCT
biomedich-176	350	7	pp	pp	ADJ
biomedich-176	350	8	.	.	PUNCT
biomedich-176	350	9	307	307	NUM
biomedich-176	350	10	-	-	SYM
biomedich-176	350	11	330	330	NUM
biomedich-176	350	12	)	)	PUNCT
biomedich-176	350	13	.	.	PUNCT
biomedich-176	351	1	springer	springer	NOUN
biomedich-176	351	2	,	,	PUNCT
biomedich-176	351	3	new	new	PROPN
biomedich-176	351	4	delhi	delhi	PROPN
biomedich-176	351	5	.	.	PUNCT
biomedich-176	352	1	reinholz	reinholz	PROPN
biomedich-176	352	2	,	,	PUNCT
biomedich-176	352	3	m.	m.	NOUN
biomedich-176	352	4	m.	m.	NOUN
biomedich-176	352	5	,	,	PUNCT
biomedich-176	352	6	bruzek	bruzek	NOUN
biomedich-176	352	7	,	,	PUNCT
biomedich-176	352	8	a.	a.	NOUN
biomedich-176	352	9	k.	k.	PROPN
biomedich-176	352	10	,	,	PUNCT
biomedich-176	352	11	visscher	visscher	PROPN
biomedich-176	352	12	,	,	PUNCT
biomedich-176	352	13	d.	d.	PROPN
biomedich-176	352	14	w.	w.	PROPN
biomedich-176	352	15	,	,	PUNCT
biomedich-176	352	16	lingle	lingle	PROPN
biomedich-176	352	17	,	,	PUNCT
biomedich-176	352	18	w.	w.	PROPN
biomedich-176	352	19	l.	l.	PROPN
biomedich-176	352	20	,	,	PUNCT
biomedich-176	352	21	schroeder	schroeder	PROPN
biomedich-176	352	22	,	,	PUNCT
biomedich-176	352	23	m.	m.	PROPN
biomedich-176	352	24	j.	j.	PROPN
biomedich-176	352	25	,	,	PUNCT
biomedich-176	352	26	perez	perez	PROPN
biomedich-176	352	27	,	,	PUNCT
biomedich-176	352	28	e.	e.	PROPN
biomedich-176	352	29	a.	a.	PROPN
biomedich-176	352	30	,	,	PUNCT
biomedich-176	352	31	&	&	CCONJ
biomedich-176	352	32	jenkins	jenkins	PROPN
biomedich-176	352	33	,	,	PUNCT
biomedich-176	352	34	r.	r.	PROPN
biomedich-176	352	35	b.	b.	PROPN
biomedich-176	352	36	(	(	PUNCT
biomedich-176	352	37	2009	2009	NUM
biomedich-176	352	38	)	)	PUNCT
biomedich-176	352	39	.	.	PUNCT
biomedich-176	353	1	breast	breast	NOUN
biomedich-176	353	2	cancer	cancer	NOUN
biomedich-176	353	3	and	and	CCONJ
biomedich-176	353	4	aneusomy	aneusomy	NOUN
biomedich-176	353	5	17	17	NUM
biomedich-176	353	6	:	:	PUNCT
biomedich-176	353	7	implications	implication	NOUN
biomedich-176	353	8	for	for	ADP
biomedich-176	353	9	carcinogenesis	carcinogenesis	NOUN
biomedich-176	353	10	and	and	CCONJ
biomedich-176	353	11	therapeutic	therapeutic	ADJ
biomedich-176	353	12	response	response	NOUN
biomedich-176	353	13	.	.	PUNCT
biomedich-176	354	1	the	the	DET
biomedich-176	354	2	lancet	lancet	PROPN
biomedich-176	354	3	oncology	oncology	NOUN
biomedich-176	354	4	,	,	PUNCT
biomedich-176	354	5	10(3	10(3	NUM
biomedich-176	354	6	)	)	PUNCT
biomedich-176	354	7	,	,	PUNCT
biomedich-176	354	8	267	267	NUM
biomedich-176	354	9	-	-	SYM
biomedich-176	354	10	277	277	NUM
biomedich-176	354	11	.	.	PUNCT
biomedich-176	355	1	reis	reis	NOUN
biomedich-176	355	2	-	-	PUNCT
biomedich-176	355	3	filho	filho	PROPN
biomedich-176	355	4	,	,	PUNCT
biomedich-176	355	5	j.	j.	PROPN
biomedich-176	355	6	s.	s.	PROPN
biomedich-176	355	7	,	,	PUNCT
biomedich-176	355	8	simpson	simpson	PROPN
biomedich-176	355	9	,	,	PUNCT
biomedich-176	355	10	p.	p.	PROPN
biomedich-176	355	11	t.	t.	PROPN
biomedich-176	355	12	,	,	PUNCT
biomedich-176	355	13	gale	gale	NOUN
biomedich-176	355	14	,	,	PUNCT
biomedich-176	355	15	t.	t.	PROPN
biomedich-176	355	16	,	,	PUNCT
biomedich-176	355	17	&	&	CCONJ
biomedich-176	355	18	lakhani	lakhani	PROPN
biomedich-176	355	19	,	,	PUNCT
biomedich-176	355	20	s.	s.	PROPN
biomedich-176	355	21	r.	r.	PROPN
biomedich-176	355	22	(	(	PUNCT
biomedich-176	355	23	2005	2005	NUM
biomedich-176	355	24	)	)	PUNCT
biomedich-176	355	25	.	.	PUNCT
biomedich-176	356	1	the	the	DET
biomedich-176	356	2	molecular	molecular	ADJ
biomedich-176	356	3	genetics	genetic	NOUN
biomedich-176	356	4	of	of	ADP
biomedich-176	356	5	breast	breast	NOUN
biomedich-176	356	6	cancer	cancer	NOUN
biomedich-176	356	7	:	:	PUNCT
biomedich-176	356	8	the	the	DET
biomedich-176	356	9	contribution	contribution	NOUN
biomedich-176	356	10	of	of	ADP
biomedich-176	356	11	comparative	comparative	ADJ
biomedich-176	356	12	genomic	genomic	NOUN
biomedich-176	356	13	hybridization	hybridization	NOUN
biomedich-176	356	14	.	.	PUNCT
biomedich-176	357	1	pathology	pathology	NOUN
biomedich-176	357	2	-	-	PUNCT
biomedich-176	357	3	research	research	NOUN
biomedich-176	357	4	and	and	CCONJ
biomedich-176	357	5	practice	practice	NOUN
biomedich-176	357	6	,	,	PUNCT
biomedich-176	357	7	201(11	201(11	NUM
biomedich-176	357	8	)	)	PUNCT
biomedich-176	357	9	,	,	PUNCT
biomedich-176	357	10	713	713	NUM
biomedich-176	357	11	-	-	SYM
biomedich-176	357	12	725	725	NUM
biomedich-176	357	13	.	.	PUNCT
biomedich-176	358	1	54	54	NUM
biomedich-176	358	2	biology	biology	NOUN
biomedich-176	358	3	,	,	PUNCT
biomedich-176	358	4	medicine	medicine	NOUN
biomedich-176	358	5	,	,	PUNCT
biomedich-176	358	6	&	&	CCONJ
biomedich-176	358	7	natural	natural	ADJ
biomedich-176	358	8	product	product	NOUN
biomedich-176	358	9	chemistry	chemistry	NOUN
biomedich-176	358	10	11	11	NUM
biomedich-176	358	11	(	(	PUNCT
biomedich-176	358	12	1	1	NUM
biomedich-176	358	13	)	)	PUNCT
biomedich-176	358	14	,	,	PUNCT
biomedich-176	358	15	2022	2022	NUM
biomedich-176	358	16	:	:	PUNCT
biomedich-176	358	17	45	45	NUM
biomedich-176	358	18	-	-	SYM
biomedich-176	358	19	54	54	NUM
biomedich-176	358	20	ribeiro	ribeiro	PROPN
biomedich-176	358	21	,	,	PUNCT
biomedich-176	358	22	i.	i.	PROPN
biomedich-176	358	23	p.	p.	PROPN
biomedich-176	358	24	,	,	PUNCT
biomedich-176	358	25	melo	melo	PROPN
biomedich-176	358	26	,	,	PUNCT
biomedich-176	358	27	j.	j.	PROPN
biomedich-176	358	28	b.	b.	PROPN
biomedich-176	358	29	,	,	PUNCT
biomedich-176	358	30	&	&	CCONJ
biomedich-176	358	31	carreira	carreira	PROPN
biomedich-176	358	32	,	,	PUNCT
biomedich-176	358	33	i.	i.	PROPN
biomedich-176	358	34	m.	m.	PROPN
biomedich-176	358	35	(	(	PUNCT
biomedich-176	358	36	2019	2019	NUM
biomedich-176	358	37	)	)	PUNCT
biomedich-176	358	38	.	.	PUNCT
biomedich-176	359	1	cytogenetics	cytogenetic	NOUN
biomedich-176	359	2	and	and	CCONJ
biomedich-176	359	3	cytogenomics	cytogenomic	NOUN
biomedich-176	359	4	evaluation	evaluation	NOUN
biomedich-176	359	5	in	in	ADP
biomedich-176	359	6	cancer	cancer	NOUN
biomedich-176	359	7	.	.	PUNCT
biomedich-176	360	1	international	international	ADJ
biomedich-176	360	2	journal	journal	NOUN
biomedich-176	360	3	of	of	ADP
biomedich-176	360	4	molecular	molecular	ADJ
biomedich-176	360	5	sciences	science	NOUN
biomedich-176	360	6	,	,	PUNCT
biomedich-176	360	7	20(19	20(19	NUM
biomedich-176	360	8	)	)	PUNCT
biomedich-176	360	9	,	,	PUNCT
biomedich-176	360	10	4711	4711	NUM
biomedich-176	360	11	.	.	PUNCT
biomedich-176	361	1	richardson	richardson	PROPN
biomedich-176	361	2	,	,	PUNCT
biomedich-176	361	3	a.	a.	PROPN
biomedich-176	361	4	l.	l.	PROPN
biomedich-176	361	5	,	,	PUNCT
biomedich-176	361	6	wang	wang	PROPN
biomedich-176	361	7	,	,	PUNCT
biomedich-176	361	8	z.	z.	PROPN
biomedich-176	361	9	c.	c.	PROPN
biomedich-176	361	10	,	,	PUNCT
biomedich-176	361	11	de	de	PROPN
biomedich-176	361	12	nicolo	nicolo	PROPN
biomedich-176	361	13	,	,	PUNCT
biomedich-176	361	14	a.	a.	PROPN
biomedich-176	361	15	,	,	PUNCT
biomedich-176	361	16	lu	lu	PROPN
biomedich-176	361	17	,	,	PUNCT
biomedich-176	361	18	x.	x.	NOUN
biomedich-176	361	19	,	,	PUNCT
biomedich-176	361	20	brown	brown	PROPN
biomedich-176	361	21	,	,	PUNCT
biomedich-176	361	22	m.	m.	NOUN
biomedich-176	361	23	,	,	PUNCT
biomedich-176	361	24	miron	miron	PROPN
biomedich-176	361	25	,	,	PUNCT
biomedich-176	361	26	a.	a.	PROPN
biomedich-176	361	27	,	,	PUNCT
biomedich-176	361	28	...	...	PUNCT
biomedich-176	361	29	&	&	CCONJ
biomedich-176	361	30	ganesan	ganesan	PROPN
biomedich-176	361	31	,	,	PUNCT
biomedich-176	361	32	s.	s.	PROPN
biomedich-176	361	33	(	(	PUNCT
biomedich-176	361	34	2006	2006	NUM
biomedich-176	361	35	)	)	PUNCT
biomedich-176	361	36	.	.	PUNCT
biomedich-176	362	1	x	x	X
biomedich-176	362	2	chromosomal	chromosomal	ADJ
biomedich-176	362	3	abnormalities	abnormality	NOUN
biomedich-176	362	4	in	in	ADP
biomedich-176	362	5	basal	basal	NOUN
biomedich-176	362	6	-	-	PUNCT
biomedich-176	362	7	like	like	ADJ
biomedich-176	362	8	human	human	ADJ
biomedich-176	362	9	breast	breast	NOUN
biomedich-176	362	10	cancer	cancer	NOUN
biomedich-176	362	11	.	.	PUNCT
biomedich-176	363	1	cancer	cancer	NOUN
biomedich-176	363	2	cell	cell	NOUN
biomedich-176	363	3	,	,	PUNCT
biomedich-176	363	4	9(2	9(2	NUM
biomedich-176	363	5	)	)	PUNCT
biomedich-176	363	6	,	,	PUNCT
biomedich-176	363	7	121	121	NUM
biomedich-176	363	8	-	-	SYM
biomedich-176	363	9	132	132	NUM
biomedich-176	363	10	.	.	PUNCT
biomedich-176	364	1	rondón	rondón	NOUN
biomedich-176	364	2	-	-	PUNCT
biomedich-176	364	3	lagos	lago	NOUN
biomedich-176	364	4	,	,	PUNCT
biomedich-176	364	5	m.	m.	NOUN
biomedich-176	364	6	,	,	PUNCT
biomedich-176	364	7	di	di	NOUN
biomedich-176	364	8	cantogno	cantogno	PROPN
biomedich-176	364	9	,	,	PUNCT
biomedich-176	364	10	l.	l.	PROPN
biomedich-176	364	11	v.	v.	PROPN
biomedich-176	364	12	,	,	PUNCT
biomedich-176	364	13	marchiò	marchiò	ADJ
biomedich-176	364	14	,	,	PUNCT
biomedich-176	364	15	c.	c.	PROPN
biomedich-176	364	16	,	,	PUNCT
biomedich-176	364	17	rangel	rangel	PROPN
biomedich-176	364	18	,	,	PUNCT
biomedich-176	364	19	n.	n.	NOUN
biomedich-176	364	20	,	,	PUNCT
biomedich-176	364	21	payan	payan	NOUN
biomedich-176	364	22	-	-	PUNCT
biomedich-176	364	23	gomez	gomez	PROPN
biomedich-176	364	24	,	,	PUNCT
biomedich-176	364	25	c.	c.	PROPN
biomedich-176	364	26	,	,	PUNCT
biomedich-176	364	27	gugliotta	gugliotta	NOUN
biomedich-176	364	28	,	,	PUNCT
biomedich-176	364	29	p.	p.	PROPN
biomedich-176	364	30	,	,	PUNCT
biomedich-176	364	31	...	...	PUNCT
biomedich-176	364	32	&	&	CCONJ
biomedich-176	364	33	sapino	sapino	PROPN
biomedich-176	364	34	,	,	PUNCT
biomedich-176	364	35	a.	a.	NOUN
biomedich-176	364	36	(	(	PUNCT
biomedich-176	364	37	2014	2014	NUM
biomedich-176	364	38	)	)	PUNCT
biomedich-176	364	39	.	.	PUNCT
biomedich-176	365	1	differences	difference	NOUN
biomedich-176	365	2	and	and	CCONJ
biomedich-176	365	3	homologies	homology	NOUN
biomedich-176	365	4	of	of	ADP
biomedich-176	365	5	chromosomal	chromosomal	ADJ
biomedich-176	365	6	alterations	alteration	NOUN
biomedich-176	365	7	within	within	ADP
biomedich-176	365	8	and	and	CCONJ
biomedich-176	365	9	between	between	ADP
biomedich-176	365	10	breast	breast	NOUN
biomedich-176	365	11	cancer	cancer	NOUN
biomedich-176	365	12	cell	cell	NOUN
biomedich-176	365	13	lines	line	NOUN
biomedich-176	365	14	:	:	PUNCT
biomedich-176	365	15	a	a	DET
biomedich-176	365	16	clustering	clustering	ADJ
biomedich-176	365	17	analysis	analysis	NOUN
biomedich-176	365	18	.	.	PUNCT
biomedich-176	366	1	molecular	molecular	ADJ
biomedich-176	366	2	cytogenetics	cytogenetic	NOUN
biomedich-176	366	3	,	,	PUNCT
biomedich-176	366	4	7(1	7(1	NUM
biomedich-176	366	5	)	)	PUNCT
biomedich-176	366	6	,	,	PUNCT
biomedich-176	366	7	8	8	NUM
biomedich-176	366	8	.	.	PUNCT
biomedich-176	366	9	schnitt	schnitt	NOUN
biomedich-176	366	10	,	,	PUNCT
biomedich-176	366	11	s.	s.	PROPN
biomedich-176	366	12	j.	j.	PROPN
biomedich-176	366	13	(	(	PUNCT
biomedich-176	366	14	2010	2010	NUM
biomedich-176	366	15	)	)	PUNCT
biomedich-176	366	16	.	.	PUNCT
biomedich-176	367	1	classification	classification	NOUN
biomedich-176	367	2	and	and	CCONJ
biomedich-176	367	3	prognosis	prognosis	NOUN
biomedich-176	367	4	of	of	ADP
biomedich-176	367	5	invasive	invasive	ADJ
biomedich-176	367	6	breast	breast	NOUN
biomedich-176	367	7	cancer	cancer	NOUN
biomedich-176	367	8	:	:	PUNCT
biomedich-176	367	9	from	from	ADP
biomedich-176	367	10	morphology	morphology	NOUN
biomedich-176	367	11	to	to	ADP
biomedich-176	367	12	molecular	molecular	ADJ
biomedich-176	367	13	taxonomy	taxonomy	NOUN
biomedich-176	367	14	.	.	PUNCT
biomedich-176	368	1	modern	modern	ADJ
biomedich-176	368	2	pathology	pathology	NOUN
biomedich-176	368	3	,	,	PUNCT
biomedich-176	368	4	23(2	23(2	NUM
biomedich-176	368	5	)	)	PUNCT
biomedich-176	368	6	,	,	PUNCT
biomedich-176	368	7	s60	s60	NOUN
biomedich-176	368	8	-	-	PUNCT
biomedich-176	368	9	s64	s64	PROPN
biomedich-176	368	10	.	.	PUNCT
biomedich-176	369	1	selig	selig	PROPN
biomedich-176	369	2	,	,	PUNCT
biomedich-176	369	3	s.	s.	PROPN
biomedich-176	369	4	,	,	PUNCT
biomedich-176	369	5	okumura	okumura	PROPN
biomedich-176	369	6	,	,	PUNCT
biomedich-176	369	7	k.	k.	PROPN
biomedich-176	369	8	,	,	PUNCT
biomedich-176	369	9	ward	ward	PROPN
biomedich-176	369	10	,	,	PUNCT
biomedich-176	369	11	d.	d.	PROPN
biomedich-176	369	12	c.	c.	PROPN
biomedich-176	369	13	,	,	PUNCT
biomedich-176	369	14	&	&	CCONJ
biomedich-176	369	15	cedar	cedar	PROPN
biomedich-176	369	16	,	,	PUNCT
biomedich-176	369	17	h.	h.	PROPN
biomedich-176	369	18	(	(	PUNCT
biomedich-176	369	19	1992	1992	NUM
biomedich-176	369	20	)	)	PUNCT
biomedich-176	369	21	.	.	PUNCT
biomedich-176	370	1	delineation	delineation	NOUN
biomedich-176	370	2	of	of	ADP
biomedich-176	370	3	dna	dna	PROPN
biomedich-176	370	4	replication	replication	NOUN
biomedich-176	370	5	time	time	NOUN
biomedich-176	370	6	zones	zone	NOUN
biomedich-176	370	7	by	by	ADP
biomedich-176	370	8	fluorescence	fluorescence	NOUN
biomedich-176	370	9	in	in	ADP
biomedich-176	370	10	situ	situ	ADJ
biomedich-176	370	11	hybridization	hybridization	NOUN
biomedich-176	370	12	.	.	PUNCT
biomedich-176	371	1	the	the	DET
biomedich-176	371	2	embo	embo	PROPN
biomedich-176	371	3	journal	journal	NOUN
biomedich-176	371	4	,	,	PUNCT
biomedich-176	371	5	11(3	11(3	NUM
biomedich-176	371	6	)	)	PUNCT
biomedich-176	371	7	,	,	PUNCT
biomedich-176	371	8	1217	1217	NUM
biomedich-176	371	9	-	-	SYM
biomedich-176	371	10	1225	1225	NUM
biomedich-176	371	11	.	.	PUNCT
biomedich-176	372	1	shakoori	shakoori	PROPN
biomedich-176	372	2	,	,	PUNCT
biomedich-176	372	3	a.	a.	PROPN
biomedich-176	372	4	r.	r.	PROPN
biomedich-176	372	5	(	(	PUNCT
biomedich-176	372	6	2017	2017	NUM
biomedich-176	372	7	)	)	PUNCT
biomedich-176	372	8	.	.	PUNCT
biomedich-176	373	1	fluorescence	fluorescence	NOUN
biomedich-176	373	2	in	in	ADP
biomedich-176	373	3	situ	situ	ADJ
biomedich-176	373	4	hybridization	hybridization	NOUN
biomedich-176	373	5	(	(	PUNCT
biomedich-176	373	6	fish	fish	NOUN
biomedich-176	373	7	)	)	PUNCT
biomedich-176	373	8	and	and	CCONJ
biomedich-176	373	9	its	its	PRON
biomedich-176	373	10	applications	application	NOUN
biomedich-176	373	11	.	.	PUNCT
biomedich-176	374	1	in	in	ADP
biomedich-176	374	2	chromosome	chromosome	NOUN
biomedich-176	374	3	structure	structure	NOUN
biomedich-176	374	4	and	and	CCONJ
biomedich-176	374	5	aberrations	aberration	NOUN
biomedich-176	374	6	(	(	PUNCT
biomedich-176	374	7	pp	pp	ADJ
biomedich-176	374	8	.	.	PUNCT
biomedich-176	375	1	343	343	NUM
biomedich-176	375	2	-	-	SYM
biomedich-176	375	3	367	367	NUM
biomedich-176	375	4	)	)	PUNCT
biomedich-176	375	5	.	.	PUNCT
biomedich-176	376	1	springer	springer	NOUN
biomedich-176	376	2	,	,	PUNCT
biomedich-176	376	3	new	new	PROPN
biomedich-176	376	4	delhi	delhi	PROPN
biomedich-176	376	5	.	.	PUNCT
biomedich-176	377	1	simpson	simpson	PROPN
biomedich-176	377	2	,	,	PUNCT
biomedich-176	377	3	p.	p.	PROPN
biomedich-176	377	4	t.	t.	PROPN
biomedich-176	377	5	,	,	PUNCT
biomedich-176	377	6	reis‐filho	reis‐filho	PROPN
biomedich-176	377	7	,	,	PUNCT
biomedich-176	377	8	j.	j.	PROPN
biomedich-176	377	9	s.	s.	PROPN
biomedich-176	377	10	,	,	PUNCT
biomedich-176	377	11	gale	gale	NOUN
biomedich-176	377	12	,	,	PUNCT
biomedich-176	377	13	t.	t.	PROPN
biomedich-176	377	14	,	,	PUNCT
biomedich-176	377	15	&	&	CCONJ
biomedich-176	377	16	lakhani	lakhani	PROPN
biomedich-176	377	17	,	,	PUNCT
biomedich-176	377	18	s.	s.	PROPN
biomedich-176	377	19	r.	r.	PROPN
biomedich-176	377	20	(	(	PUNCT
biomedich-176	377	21	2005	2005	NUM
biomedich-176	377	22	)	)	PUNCT
biomedich-176	377	23	.	.	PUNCT
biomedich-176	378	1	molecular	molecular	ADJ
biomedich-176	378	2	evolution	evolution	NOUN
biomedich-176	378	3	of	of	ADP
biomedich-176	378	4	breast	breast	NOUN
biomedich-176	378	5	cancer	cancer	NOUN
biomedich-176	378	6	.	.	PUNCT
biomedich-176	379	1	the	the	DET
biomedich-176	379	2	journal	journal	PROPN
biomedich-176	379	3	of	of	ADP
biomedich-176	379	4	pathology	pathology	PROPN
biomedich-176	379	5	:	:	PUNCT
biomedich-176	379	6	a	a	DET
biomedich-176	379	7	journal	journal	NOUN
biomedich-176	379	8	of	of	ADP
biomedich-176	379	9	the	the	DET
biomedich-176	379	10	pathological	pathological	ADJ
biomedich-176	379	11	society	society	NOUN
biomedich-176	379	12	of	of	ADP
biomedich-176	379	13	great	great	ADJ
biomedich-176	379	14	britain	britain	PROPN
biomedich-176	379	15	and	and	CCONJ
biomedich-176	379	16	ireland	ireland	PROPN
biomedich-176	379	17	,	,	PUNCT
biomedich-176	379	18	205(2	205(2	NUM
biomedich-176	379	19	)	)	PUNCT
biomedich-176	379	20	,	,	PUNCT
biomedich-176	379	21	248	248	NUM
biomedich-176	379	22	-	-	SYM
biomedich-176	379	23	254	254	NUM
biomedich-176	379	24	.	.	PUNCT
biomedich-176	380	1	smail	smail	NOUN
biomedich-176	380	2	,	,	PUNCT
biomedich-176	380	3	h.	h.	PROPN
biomedich-176	380	4	o.	o.	PROPN
biomedich-176	380	5	(	(	PUNCT
biomedich-176	380	6	2020	2020	NUM
biomedich-176	380	7	)	)	PUNCT
biomedich-176	380	8	.	.	PUNCT
biomedich-176	381	1	dermatoglyphics	dermatoglyphic	NOUN
biomedich-176	381	2	in	in	ADP
biomedich-176	381	3	common	common	ADJ
biomedich-176	381	4	:	:	PUNCT
biomedich-176	381	5	genetic	genetic	ADJ
biomedich-176	381	6	disorders	disorder	NOUN
biomedich-176	381	7	and	and	CCONJ
biomedich-176	381	8	cancers	cancer	NOUN
biomedich-176	381	9	.	.	PUNCT
biomedich-176	382	1	micromedicine	micromedicine	NOUN
biomedich-176	382	2	,	,	PUNCT
biomedich-176	382	3	8(2	8(2	NUM
biomedich-176	382	4	)	)	PUNCT
biomedich-176	382	5	,	,	PUNCT
biomedich-176	382	6	55	55	NUM
biomedich-176	382	7	-	-	SYM
biomedich-176	382	8	62	62	NUM
biomedich-176	382	9	.	.	PUNCT
biomedich-176	383	1	smail	smail	NOUN
biomedich-176	383	2	,	,	PUNCT
biomedich-176	383	3	h.o	h.o	PROPN
biomedich-176	383	4	.	.	PROPN
biomedich-176	383	5	,	,	PUNCT
biomedich-176	383	6	2016	2016	NUM
biomedich-176	383	7	.	.	PUNCT
biomedich-176	384	1	qualitative	qualitative	ADJ
biomedich-176	384	2	and	and	CCONJ
biomedich-176	384	3	quantitative	quantitative	ADJ
biomedich-176	384	4	identification	identification	NOUN
biomedich-176	384	5	of	of	ADP
biomedich-176	384	6	dna	dna	PROPN
biomedich-176	384	7	methylation	methylation	NOUN
biomedich-176	384	8	changes	change	NOUN
biomedich-176	384	9	in	in	ADP
biomedich-176	384	10	blood	blood	NOUN
biomedich-176	384	11	of	of	ADP
biomedich-176	384	12	the	the	DET
biomedich-176	384	13	breast	breast	NOUN
biomedich-176	384	14	cancer	cancer	NOUN
biomedich-176	384	15	patients	patient	NOUN
biomedich-176	384	16	(	(	PUNCT
biomedich-176	384	17	msc	msc	PROPN
biomedich-176	384	18	thesis	thesis	PROPN
biomedich-176	384	19	,	,	PUNCT
biomedich-176	384	20	university	university	NOUN
biomedich-176	384	21	of	of	ADP
biomedich-176	384	22	sulaimani	sulaimani	NOUN
biomedich-176	384	23	)	)	PUNCT
biomedich-176	384	24	.	.	PUNCT
biomedich-176	385	1	speicher	speicher	NOUN
biomedich-176	385	2	,	,	PUNCT
biomedich-176	385	3	m.	m.	PROPN
biomedich-176	385	4	r.	r.	PROPN
biomedich-176	385	5	,	,	PUNCT
biomedich-176	385	6	&	&	CCONJ
biomedich-176	385	7	carter	carter	PROPN
biomedich-176	385	8	,	,	PUNCT
biomedich-176	385	9	n.	n.	PROPN
biomedich-176	385	10	p.	p.	PROPN
biomedich-176	386	1	(	(	PUNCT
biomedich-176	386	2	2005	2005	NUM
biomedich-176	386	3	)	)	PUNCT
biomedich-176	386	4	.	.	PUNCT
biomedich-176	387	1	the	the	DET
biomedich-176	387	2	new	new	ADJ
biomedich-176	387	3	cytogenetics	cytogenetic	NOUN
biomedich-176	387	4	:	:	PUNCT
biomedich-176	387	5	blurring	blur	VERB
biomedich-176	387	6	the	the	DET
biomedich-176	387	7	boundaries	boundary	NOUN
biomedich-176	387	8	with	with	ADP
biomedich-176	387	9	molecular	molecular	ADJ
biomedich-176	387	10	biology	biology	NOUN
biomedich-176	387	11	.	.	PUNCT
biomedich-176	388	1	nature	nature	NOUN
biomedich-176	388	2	reviews	review	VERB
biomedich-176	388	3	genetics	genetic	NOUN
biomedich-176	388	4	,	,	PUNCT
biomedich-176	388	5	6(10	6(10	NUM
biomedich-176	388	6	)	)	PUNCT
biomedich-176	388	7	,	,	PUNCT
biomedich-176	388	8	782	782	NUM
biomedich-176	388	9	-	-	SYM
biomedich-176	388	10	792	792	NUM
biomedich-176	388	11	.	.	PUNCT
biomedich-176	389	1	thompson	thompson	PROPN
biomedich-176	389	2	,	,	PUNCT
biomedich-176	389	3	c.	c.	PROPN
biomedich-176	389	4	t.	t.	PROPN
biomedich-176	389	5	,	,	PUNCT
biomedich-176	389	6	&	&	CCONJ
biomedich-176	389	7	gray	gray	PROPN
biomedich-176	389	8	,	,	PUNCT
biomedich-176	389	9	j.	j.	PROPN
biomedich-176	389	10	w.	w.	PROPN
biomedich-176	389	11	(	(	PUNCT
biomedich-176	389	12	1993	1993	NUM
biomedich-176	389	13	)	)	PUNCT
biomedich-176	389	14	.	.	PUNCT
biomedich-176	390	1	cytogenetic	cytogenetic	ADJ
biomedich-176	390	2	profiling	profiling	NOUN
biomedich-176	390	3	using	use	VERB
biomedich-176	390	4	fluorescence	fluorescence	NOUN
biomedich-176	390	5	in	in	ADP
biomedich-176	390	6	situ	situ	ADJ
biomedich-176	390	7	hybridization	hybridization	NOUN
biomedich-176	390	8	(	(	PUNCT
biomedich-176	390	9	fish	fish	NOUN
biomedich-176	390	10	)	)	PUNCT
biomedich-176	390	11	and	and	CCONJ
biomedich-176	390	12	comparative	comparative	ADJ
biomedich-176	390	13	genomic	genomic	NOUN
biomedich-176	390	14	hybridization	hybridization	NOUN
biomedich-176	390	15	(	(	PUNCT
biomedich-176	390	16	cgh	cgh	PROPN
biomedich-176	390	17	)	)	PUNCT
biomedich-176	390	18	.	.	PUNCT
biomedich-176	391	1	journal	journal	NOUN
biomedich-176	391	2	of	of	ADP
biomedich-176	391	3	cellular	cellular	ADJ
biomedich-176	391	4	biochemistry	biochemistry	NOUN
biomedich-176	391	5	,	,	PUNCT
biomedich-176	391	6	53(s17	53(s17	NUM
biomedich-176	391	7	g	g	NOUN
biomedich-176	391	8	)	)	PUNCT
biomedich-176	391	9	,	,	PUNCT
biomedich-176	391	10	139	139	NUM
biomedich-176	391	11	-	-	SYM
biomedich-176	391	12	143	143	NUM
biomedich-176	391	13	.	.	PUNCT
biomedich-176	392	1	turner	turner	PROPN
biomedich-176	392	2	,	,	PUNCT
biomedich-176	392	3	t.	t.	PROPN
biomedich-176	392	4	h.	h.	PROPN
biomedich-176	392	5	,	,	PUNCT
biomedich-176	392	6	alzubi	alzubi	PROPN
biomedich-176	392	7	,	,	PUNCT
biomedich-176	392	8	m.	m.	NOUN
biomedich-176	392	9	a.	a.	NOUN
biomedich-176	392	10	,	,	PUNCT
biomedich-176	392	11	sohal	sohal	NOUN
biomedich-176	392	12	,	,	PUNCT
biomedich-176	392	13	s.	s.	PROPN
biomedich-176	392	14	s.	s.	PROPN
biomedich-176	392	15	,	,	PUNCT
biomedich-176	392	16	olex	olex	ADJ
biomedich-176	392	17	,	,	PUNCT
biomedich-176	392	18	a.	a.	PROPN
biomedich-176	392	19	l.	l.	PROPN
biomedich-176	392	20	,	,	PUNCT
biomedich-176	392	21	dozmorov	dozmorov	PROPN
biomedich-176	392	22	,	,	PUNCT
biomedich-176	392	23	m.	m.	NOUN
biomedich-176	392	24	g.	g.	PROPN
biomedich-176	392	25	,	,	PUNCT
biomedich-176	392	26	&	&	CCONJ
biomedich-176	392	27	harrell	harrell	PROPN
biomedich-176	392	28	,	,	PUNCT
biomedich-176	392	29	j.	j.	PROPN
biomedich-176	392	30	c.	c.	PROPN
biomedich-176	392	31	(	(	PUNCT
biomedich-176	392	32	2018	2018	NUM
biomedich-176	392	33	)	)	PUNCT
biomedich-176	392	34	.	.	PUNCT
biomedich-176	393	1	characterizing	characterize	VERB
biomedich-176	393	2	the	the	DET
biomedich-176	393	3	efficacy	efficacy	NOUN
biomedich-176	393	4	of	of	ADP
biomedich-176	393	5	cancer	cancer	NOUN
biomedich-176	393	6	therapeutics	therapeutic	NOUN
biomedich-176	393	7	in	in	ADP
biomedich-176	393	8	patient	patient	NOUN
biomedich-176	393	9	-	-	PUNCT
biomedich-176	393	10	derived	derive	VERB
biomedich-176	393	11	xenograft	xenograft	NOUN
biomedich-176	393	12	models	model	NOUN
biomedich-176	393	13	of	of	ADP
biomedich-176	393	14	metastatic	metastatic	ADJ
biomedich-176	393	15	breast	breast	NOUN
biomedich-176	393	16	cancer	cancer	NOUN
biomedich-176	393	17	.	.	PUNCT
biomedich-176	394	1	breast	breast	NOUN
biomedich-176	394	2	cancer	cancer	NOUN
biomedich-176	394	3	research	research	NOUN
biomedich-176	394	4	and	and	CCONJ
biomedich-176	394	5	treatment	treatment	NOUN
biomedich-176	394	6	,	,	PUNCT
biomedich-176	394	7	170(2	170(2	NUM
biomedich-176	394	8	)	)	PUNCT
biomedich-176	394	9	,	,	PUNCT
biomedich-176	394	10	221	221	NUM
biomedich-176	394	11	-	-	SYM
biomedich-176	394	12	234	234	NUM
biomedich-176	394	13	.	.	PUNCT
biomedich-176	395	1	ueno	ueno	PROPN
biomedich-176	395	2	,	,	PUNCT
biomedich-176	395	3	t.	t.	PROPN
biomedich-176	395	4	,	,	PUNCT
biomedich-176	395	5	emi	emi	PROPN
biomedich-176	395	6	,	,	PUNCT
biomedich-176	395	7	m.	m.	NOUN
biomedich-176	395	8	,	,	PUNCT
biomedich-176	395	9	sato	sato	PROPN
biomedich-176	395	10	,	,	PUNCT
biomedich-176	395	11	h.	h.	PROPN
biomedich-176	395	12	,	,	PUNCT
biomedich-176	395	13	ito	ito	PROPN
biomedich-176	395	14	,	,	PUNCT
biomedich-176	395	15	n.	n.	NOUN
biomedich-176	395	16	,	,	PUNCT
biomedich-176	395	17	muta	muta	PROPN
biomedich-176	395	18	,	,	PUNCT
biomedich-176	395	19	m.	m.	NOUN
biomedich-176	395	20	,	,	PUNCT
biomedich-176	395	21	kuroi	kuroi	PROPN
biomedich-176	395	22	,	,	PUNCT
biomedich-176	395	23	k.	k.	PROPN
biomedich-176	395	24	,	,	PUNCT
biomedich-176	395	25	&	&	CCONJ
biomedich-176	395	26	toi	toi	PROPN
biomedich-176	395	27	,	,	PUNCT
biomedich-176	395	28	m.	m.	NOUN
biomedich-176	395	29	(	(	PUNCT
biomedich-176	395	30	2012	2012	NUM
biomedich-176	395	31	)	)	PUNCT
biomedich-176	395	32	.	.	PUNCT
biomedich-176	396	1	genome	genome	NOUN
biomedich-176	396	2	-	-	PUNCT
biomedich-176	396	3	wide	wide	ADJ
biomedich-176	396	4	copy	copy	NOUN
biomedich-176	396	5	number	number	NOUN
biomedich-176	396	6	analysis	analysis	NOUN
biomedich-176	396	7	in	in	ADP
biomedich-176	396	8	primary	primary	ADJ
biomedich-176	396	9	breast	breast	NOUN
biomedich-176	396	10	cancer	cancer	NOUN
biomedich-176	396	11	.	.	PUNCT
biomedich-176	397	1	expert	expert	ADJ
biomedich-176	397	2	opinion	opinion	NOUN
biomedich-176	397	3	on	on	ADP
biomedich-176	397	4	therapeutic	therapeutic	ADJ
biomedich-176	397	5	targets	target	NOUN
biomedich-176	397	6	,	,	PUNCT
biomedich-176	397	7	16(sup1	16(sup1	NUM
biomedich-176	397	8	)	)	PUNCT
biomedich-176	397	9	,	,	PUNCT
biomedich-176	397	10	s31	s31	NOUN
biomedich-176	397	11	-	-	PUNCT
biomedich-176	397	12	s35	s35	NOUN
biomedich-176	397	13	.	.	PUNCT
biomedich-176	398	1	varella‐garcia	varella‐garcia	PROPN
biomedich-176	398	2	,	,	PUNCT
biomedich-176	398	3	m.	m.	NOUN
biomedich-176	398	4	(	(	PUNCT
biomedich-176	398	5	2003	2003	NUM
biomedich-176	398	6	)	)	PUNCT
biomedich-176	398	7	.	.	PUNCT
biomedich-176	399	1	molecular	molecular	ADJ
biomedich-176	399	2	cytogenetics	cytogenetic	NOUN
biomedich-176	399	3	in	in	ADP
biomedich-176	399	4	solid	solid	ADJ
biomedich-176	399	5	tumors	tumor	NOUN
biomedich-176	399	6	:	:	PUNCT
biomedich-176	399	7	laboratorial	laboratorial	ADJ
biomedich-176	399	8	tool	tool	NOUN
biomedich-176	399	9	for	for	ADP
biomedich-176	399	10	diagnosis	diagnosis	NOUN
biomedich-176	399	11	,	,	PUNCT
biomedich-176	399	12	prognosis	prognosis	NOUN
biomedich-176	399	13	,	,	PUNCT
biomedich-176	399	14	and	and	CCONJ
biomedich-176	399	15	therapy	therapy	NOUN
biomedich-176	399	16	.	.	PUNCT
biomedich-176	400	1	the	the	DET
biomedich-176	400	2	oncologist	oncologist	NOUN
biomedich-176	400	3	,	,	PUNCT
biomedich-176	400	4	8(1	8(1	NOUN
biomedich-176	400	5	)	)	PUNCT
biomedich-176	400	6	,	,	PUNCT
biomedich-176	400	7	45	45	NUM
biomedich-176	400	8	-	-	SYM
biomedich-176	400	9	58	58	NUM
biomedich-176	400	10	.	.	PUNCT
biomedich-176	401	1	waminal	waminal	ADJ
biomedich-176	401	2	,	,	PUNCT
biomedich-176	401	3	n.	n.	PROPN
biomedich-176	401	4	e.	e.	PROPN
biomedich-176	401	5	,	,	PUNCT
biomedich-176	401	6	pellerin	pellerin	PROPN
biomedich-176	401	7	,	,	PUNCT
biomedich-176	401	8	r.	r.	PROPN
biomedich-176	401	9	j.	j.	PROPN
biomedich-176	401	10	,	,	PUNCT
biomedich-176	401	11	kim	kim	PROPN
biomedich-176	401	12	,	,	PUNCT
biomedich-176	401	13	n.	n.	PROPN
biomedich-176	401	14	s.	s.	PROPN
biomedich-176	401	15	,	,	PUNCT
biomedich-176	401	16	jayakodi	jayakodi	PROPN
biomedich-176	401	17	,	,	PUNCT
biomedich-176	401	18	m.	m.	NOUN
biomedich-176	401	19	,	,	PUNCT
biomedich-176	401	20	park	park	NOUN
biomedich-176	401	21	,	,	PUNCT
biomedich-176	401	22	j.	j.	PROPN
biomedich-176	401	23	y.	y.	PROPN
biomedich-176	401	24	,	,	PUNCT
biomedich-176	401	25	yang	yang	PROPN
biomedich-176	401	26	,	,	PUNCT
biomedich-176	401	27	t.	t.	PROPN
biomedich-176	401	28	j.	j.	PROPN
biomedich-176	401	29	,	,	PUNCT
biomedich-176	401	30	&	&	CCONJ
biomedich-176	401	31	kim	kim	PROPN
biomedich-176	401	32	,	,	PUNCT
biomedich-176	401	33	h.	h.	PROPN
biomedich-176	401	34	h.	h.	PROPN
biomedich-176	401	35	(	(	PUNCT
biomedich-176	401	36	2018	2018	NUM
biomedich-176	401	37	)	)	PUNCT
biomedich-176	401	38	.	.	PUNCT
biomedich-176	402	1	rapid	rapid	ADJ
biomedich-176	402	2	and	and	CCONJ
biomedich-176	402	3	efficient	efficient	ADJ
biomedich-176	402	4	fish	fish	NOUN
biomedich-176	402	5	using	use	VERB
biomedich-176	402	6	pre	pre	ADJ
biomedich-176	402	7	-	-	ADJ
biomedich-176	402	8	labeled	label	VERB
biomedich-176	402	9	oligomer	oligomer	ADJ
biomedich-176	402	10	probes	probe	NOUN
biomedich-176	402	11	.	.	PUNCT
biomedich-176	403	1	scientific	scientific	ADJ
biomedich-176	403	2	reports	report	NOUN
biomedich-176	403	3	,	,	PUNCT
biomedich-176	403	4	8(1	8(1	NOUN
biomedich-176	403	5	)	)	PUNCT
biomedich-176	403	6	,	,	PUNCT
biomedich-176	403	7	1	1	NUM
biomedich-176	403	8	-	-	SYM
biomedich-176	403	9	10	10	NUM
biomedich-176	403	10	.	.	PUNCT
biomedich-176	404	1	watters	watter	NOUN
biomedich-176	404	2	,	,	PUNCT
biomedich-176	404	3	a.	a.	PROPN
biomedich-176	404	4	d.	d.	PROPN
biomedich-176	404	5	,	,	PUNCT
biomedich-176	404	6	going	go	VERB
biomedich-176	404	7	,	,	PUNCT
biomedich-176	404	8	j.	j.	PROPN
biomedich-176	404	9	j.	j.	PROPN
biomedich-176	404	10	,	,	PUNCT
biomedich-176	404	11	cooke	cooke	PROPN
biomedich-176	404	12	,	,	PUNCT
biomedich-176	404	13	t.	t.	PROPN
biomedich-176	404	14	g.	g.	PROPN
biomedich-176	404	15	,	,	PUNCT
biomedich-176	404	16	&	&	CCONJ
biomedich-176	404	17	bartlett	bartlett	PROPN
biomedich-176	404	18	,	,	PUNCT
biomedich-176	404	19	j.	j.	PROPN
biomedich-176	404	20	m.	m.	PROPN
biomedich-176	404	21	s.	s.	PROPN
biomedich-176	404	22	(	(	PUNCT
biomedich-176	404	23	2003	2003	NUM
biomedich-176	404	24	)	)	PUNCT
biomedich-176	404	25	.	.	PUNCT
biomedich-176	405	1	chromosome	chromosome	NOUN
biomedich-176	405	2	17	17	NUM
biomedich-176	405	3	aneusomy	aneusomy	NOUN
biomedich-176	405	4	is	be	AUX
biomedich-176	405	5	associated	associate	VERB
biomedich-176	405	6	with	with	ADP
biomedich-176	405	7	poor	poor	ADJ
biomedich-176	405	8	prognostic	prognostic	ADJ
biomedich-176	405	9	factors	factor	NOUN
biomedich-176	405	10	in	in	ADP
biomedich-176	405	11	invasive	invasive	ADJ
biomedich-176	405	12	breast	breast	NOUN
biomedich-176	405	13	carcinoma	carcinoma	NOUN
biomedich-176	405	14	.	.	PUNCT
biomedich-176	406	1	breast	breast	NOUN
biomedich-176	406	2	cancer	cancer	NOUN
biomedich-176	406	3	research	research	NOUN
biomedich-176	406	4	and	and	CCONJ
biomedich-176	406	5	treatment	treatment	NOUN
biomedich-176	406	6	,	,	PUNCT
biomedich-176	406	7	77(2	77(2	NOUN
biomedich-176	406	8	)	)	PUNCT
biomedich-176	406	9	,	,	PUNCT
biomedich-176	406	10	109	109	NUM
biomedich-176	406	11	-	-	SYM
biomedich-176	406	12	114	114	NUM
biomedich-176	406	13	.	.	PUNCT
biomedich-176	407	1	weigelt	weigelt	PROPN
biomedich-176	407	2	,	,	PUNCT
biomedich-176	407	3	b.	b.	PROPN
biomedich-176	407	4	,	,	PUNCT
biomedich-176	407	5	mackay	mackay	PROPN
biomedich-176	407	6	,	,	PUNCT
biomedich-176	407	7	a.	a.	PROPN
biomedich-176	407	8	,	,	PUNCT
biomedich-176	407	9	a'hern	a'hern	PROPN
biomedich-176	407	10	,	,	PUNCT
biomedich-176	407	11	r.	r.	PROPN
biomedich-176	407	12	,	,	PUNCT
biomedich-176	407	13	natrajan	natrajan	PROPN
biomedich-176	407	14	,	,	PUNCT
biomedich-176	407	15	r.	r.	PROPN
biomedich-176	407	16	,	,	PUNCT
biomedich-176	407	17	tan	tan	PROPN
biomedich-176	407	18	,	,	PUNCT
biomedich-176	407	19	d.	d.	PROPN
biomedich-176	407	20	s.	s.	PROPN
biomedich-176	407	21	,	,	PUNCT
biomedich-176	407	22	dowsett	dowsett	NOUN
biomedich-176	407	23	,	,	PUNCT
biomedich-176	407	24	m.	m.	NOUN
biomedich-176	407	25	,	,	PUNCT
biomedich-176	407	26	...	...	PUNCT
biomedich-176	407	27	&	&	CCONJ
biomedich-176	407	28	reis	reis	NOUN
biomedich-176	407	29	-	-	PUNCT
biomedich-176	407	30	filho	filho	PROPN
biomedich-176	407	31	,	,	PUNCT
biomedich-176	407	32	j.	j.	PROPN
biomedich-176	407	33	s.	s.	PROPN
biomedich-176	407	34	(	(	PUNCT
biomedich-176	407	35	2010	2010	NUM
biomedich-176	407	36	)	)	PUNCT
biomedich-176	407	37	.	.	PUNCT
biomedich-176	408	1	breast	breast	NOUN
biomedich-176	408	2	cancer	cancer	NOUN
biomedich-176	408	3	molecular	molecular	ADJ
biomedich-176	408	4	profiling	profiling	NOUN
biomedich-176	408	5	with	with	ADP
biomedich-176	408	6	single	single	ADJ
biomedich-176	408	7	sample	sample	NOUN
biomedich-176	408	8	predictors	predictor	NOUN
biomedich-176	408	9	:	:	PUNCT
biomedich-176	408	10	a	a	DET
biomedich-176	408	11	retrospective	retrospective	ADJ
biomedich-176	408	12	analysis	analysis	NOUN
biomedich-176	408	13	.	.	PUNCT
biomedich-176	409	1	the	the	DET
biomedich-176	409	2	lancet	lancet	PROPN
biomedich-176	409	3	oncology	oncology	NOUN
biomedich-176	409	4	,	,	PUNCT
biomedich-176	409	5	11(4	11(4	NUM
biomedich-176	409	6	)	)	PUNCT
biomedich-176	409	7	,	,	PUNCT
biomedich-176	409	8	339	339	NUM
biomedich-176	409	9	-	-	SYM
biomedich-176	409	10	349	349	NUM
biomedich-176	409	11	.	.	PUNCT
biomedich-176	410	1	zhang	zhang	PROPN
biomedich-176	410	2	,	,	PUNCT
biomedich-176	410	3	j.	j.	PROPN
biomedich-176	410	4	,	,	PUNCT
biomedich-176	410	5	zhang	zhang	PROPN
biomedich-176	410	6	,	,	PUNCT
biomedich-176	410	7	h.	h.	PROPN
biomedich-176	410	8	,	,	PUNCT
biomedich-176	410	9	xu	xu	PROPN
biomedich-176	410	10	,	,	PUNCT
biomedich-176	410	11	x.	x.	PROPN
biomedich-176	410	12	,	,	PUNCT
biomedich-176	410	13	wang	wang	PROPN
biomedich-176	410	14	,	,	PUNCT
biomedich-176	410	15	m.	m.	NOUN
biomedich-176	410	16	,	,	PUNCT
biomedich-176	410	17	&	&	CCONJ
biomedich-176	410	18	yu	yu	PROPN
biomedich-176	410	19	,	,	PUNCT
biomedich-176	410	20	z.	z.	PROPN
biomedich-176	410	21	(	(	PUNCT
biomedich-176	410	22	2015	2015	NUM
biomedich-176	410	23	)	)	PUNCT
biomedich-176	410	24	.	.	PUNCT
biomedich-176	411	1	comparative	comparative	ADJ
biomedich-176	411	2	genomic	genomic	ADJ
biomedich-176	411	3	hybridization	hybridization	NOUN
biomedich-176	411	4	analysis	analysis	NOUN
biomedich-176	411	5	of	of	ADP
biomedich-176	411	6	invasive	invasive	ADJ
biomedich-176	411	7	ductal	ductal	ADJ
biomedich-176	411	8	breast	breast	NOUN
biomedich-176	411	9	carcinomas	carcinoma	NOUN
biomedich-176	411	10	in	in	ADP
biomedich-176	411	11	the	the	DET
biomedich-176	411	12	chinese	chinese	ADJ
biomedich-176	411	13	population	population	NOUN
biomedich-176	411	14	.	.	PUNCT
biomedich-176	412	1	oncology	oncology	NOUN
biomedich-176	412	2	letters	letter	NOUN
biomedich-176	412	3	,	,	PUNCT
biomedich-176	412	4	10(4	10(4	NUM
biomedich-176	412	5	)	)	PUNCT
biomedich-176	412	6	,	,	PUNCT
biomedich-176	412	7	2100	2100	NUM
biomedich-176	412	8	-	-	SYM
biomedich-176	412	9	2106	2106	NUM
biomedich-176	412	10	.	.	PUNCT