id	sid	tid	token	lemma	pos
biomedich-274	1	1	biology	biology	NOUN
biomedich-274	1	2	,	,	PUNCT
biomedich-274	1	3	medicine	medicine	NOUN
biomedich-274	1	4	,	,	PUNCT
biomedich-274	1	5	&	&	CCONJ
biomedich-274	1	6	natural	natural	ADJ
biomedich-274	1	7	product	product	NOUN
biomedich-274	1	8	chemistry	chemistry	NOUN
biomedich-274	1	9	issn	issn	VERB
biomedich-274	1	10	2089	2089	NUM
biomedich-274	1	11	-	-	SYM
biomedich-274	1	12	6514	6514	NUM
biomedich-274	1	13	(	(	PUNCT
biomedich-274	1	14	paper	paper	NOUN
biomedich-274	1	15	)	)	PUNCT
biomedich-274	1	16	volume	volume	NOUN
biomedich-274	1	17	12	12	NUM
biomedich-274	1	18	,	,	PUNCT
biomedich-274	1	19	number	number	NOUN
biomedich-274	1	20	1	1	NUM
biomedich-274	1	21	,	,	PUNCT
biomedich-274	1	22	april	april	PROPN
biomedich-274	1	23	2023	2023	NUM
biomedich-274	2	1	|	|	ADV
biomedich-274	2	2	pages	page	NOUN
biomedich-274	2	3	:	:	PUNCT
biomedich-274	2	4	97	97	NUM
biomedich-274	2	5	-	-	SYM
biomedich-274	2	6	108	108	NUM
biomedich-274	2	7	|	|	ADV
biomedich-274	2	8	doi	doi	NOUN
biomedich-274	2	9	:	:	PUNCT
biomedich-274	2	10	10.14421	10.14421	NUM
biomedich-274	2	11	/	/	SYM
biomedich-274	2	12	biomedich.2023.121.97	biomedich.2023.121.97	NOUN
biomedich-274	2	13	-	-	SYM
biomedich-274	2	14	108	108	NUM
biomedich-274	2	15	issn	issn	PROPN
biomedich-274	2	16	2540	2540	NUM
biomedich-274	2	17	-	-	SYM
biomedich-274	2	18	9328	9328	NUM
biomedich-274	2	19	(	(	PUNCT
biomedich-274	2	20	online	online	ADJ
biomedich-274	2	21	)	)	PUNCT
biomedich-274	2	22	potential	potential	ADJ
biomedich-274	2	23	inhibition	inhibition	NOUN
biomedich-274	2	24	of	of	ADP
biomedich-274	2	25	ace2	ace2	NOUN
biomedich-274	2	26	membrane	membrane	NOUN
biomedich-274	2	27	protein	protein	NOUN
biomedich-274	2	28	by	by	ADP
biomedich-274	2	29	flavone	flavone	NOUN
biomedich-274	2	30	glycosides	glycoside	NOUN
biomedich-274	2	31	for	for	ADP
biomedich-274	2	32	blocking	block	VERB
biomedich-274	2	33	entrance	entrance	NOUN
biomedich-274	2	34	of	of	ADP
biomedich-274	2	35	sarscov-2	sarscov-2	NUM
biomedich-274	2	36	into	into	ADP
biomedich-274	2	37	the	the	DET
biomedich-274	2	38	cells	cell	NOUN
biomedich-274	2	39	;	;	PUNCT
biomedich-274	2	40	a	a	DET
biomedich-274	2	41	computational	computational	ADJ
biomedich-274	2	42	study	study	NOUN
biomedich-274	2	43	ahsan	ahsan	PROPN
biomedich-274	2	44	ibrahim	ibrahim	PROPN
biomedich-274	3	1	*	*	PROPN
biomedich-274	3	2	,	,	PUNCT
biomedich-274	3	3	ehtisham	ehtisham	PROPN
biomedich-274	3	4	ul	ul	INTJ
biomedich-274	3	5	haq	haq	PROPN
biomedich-274	3	6	shifa	shifa	PROPN
biomedich-274	3	7	tameer	tameer	PROPN
biomedich-274	3	8	-	-	PUNCT
biomedich-274	3	9	e	e	NOUN
biomedich-274	3	10	-	-	PROPN
biomedich-274	3	11	millat	millat	ADJ
biomedich-274	3	12	university	university	NOUN
biomedich-274	3	13	,	,	PUNCT
biomedich-274	3	14	islamabad-44000	islamabad-44000	NOUN
biomedich-274	3	15	,	,	PUNCT
biomedich-274	3	16	tel	tel	PROPN
biomedich-274	3	17	.	.	PROPN
biomedich-274	3	18	+9251	+9251	NUM
biomedich-274	3	19	-	-	SYM
biomedich-274	3	20	8438061	8438061	NUM
biomedich-274	3	21	fax	fax	NOUN
biomedich-274	3	22	.	.	PROPN
biomedich-274	3	23	+9251	+9251	NUM
biomedich-274	3	24	-	-	PUNCT
biomedich-274	3	25	8438059	8438059	NUM
biomedich-274	3	26	,	,	PUNCT
biomedich-274	3	27	pakistan	pakistan	PROPN
biomedich-274	3	28	.	.	PUNCT
biomedich-274	4	1	corresponding	correspond	VERB
biomedich-274	4	2	author	author	NOUN
biomedich-274	4	3	*	*	PROPN
biomedich-274	4	4	ahsan.scps@stmu.edu.pk	ahsan.scps@stmu.edu.pk	PROPN
biomedich-274	4	5	manuscript	manuscript	NOUN
biomedich-274	4	6	received	receive	VERB
biomedich-274	4	7	:	:	PUNCT
biomedich-274	4	8	07	07	NUM
biomedich-274	4	9	october	october	PROPN
biomedich-274	4	10	,	,	PUNCT
biomedich-274	4	11	2022	2022	NUM
biomedich-274	4	12	.	.	PUNCT
biomedich-274	5	1	revision	revision	NOUN
biomedich-274	5	2	accepted	accept	VERB
biomedich-274	5	3	:	:	PUNCT
biomedich-274	5	4	07	07	NUM
biomedich-274	5	5	december	december	PROPN
biomedich-274	5	6	,	,	PUNCT
biomedich-274	5	7	2022	2022	NUM
biomedich-274	5	8	.	.	PUNCT
biomedich-274	6	1	published	publish	VERB
biomedich-274	6	2	:	:	PUNCT
biomedich-274	6	3	10	10	NUM
biomedich-274	6	4	january	january	PROPN
biomedich-274	6	5	,	,	PUNCT
biomedich-274	6	6	2023	2023	NUM
biomedich-274	6	7	.	.	PUNCT
biomedich-274	7	1	abstract	abstract	ADJ
biomedich-274	7	2	severe	severe	ADJ
biomedich-274	7	3	acute	acute	ADJ
biomedich-274	7	4	respiratory	respiratory	ADJ
biomedich-274	7	5	syndrome	syndrome	NOUN
biomedich-274	7	6	coronavirus	coronavirus	NOUN
biomedich-274	7	7	2	2	NUM
biomedich-274	7	8	(	(	PUNCT
biomedich-274	7	9	sarscov-2	sarscov-2	NUM
biomedich-274	7	10	)	)	PUNCT
biomedich-274	7	11	,	,	PUNCT
biomedich-274	7	12	since	since	SCONJ
biomedich-274	7	13	its	its	PRON
biomedich-274	7	14	emergence	emergence	NOUN
biomedich-274	7	15	in	in	ADP
biomedich-274	7	16	wuhan	wuhan	PROPN
biomedich-274	7	17	city	city	PROPN
biomedich-274	7	18	of	of	ADP
biomedich-274	7	19	china	china	PROPN
biomedich-274	7	20	in	in	ADP
biomedich-274	7	21	late	late	ADJ
biomedich-274	7	22	2019	2019	NUM
biomedich-274	7	23	,	,	PUNCT
biomedich-274	7	24	had	have	AUX
biomedich-274	7	25	been	be	AUX
biomedich-274	7	26	a	a	DET
biomedich-274	7	27	dilemma	dilemma	NOUN
biomedich-274	7	28	for	for	ADP
biomedich-274	7	29	the	the	DET
biomedich-274	7	30	global	global	ADJ
biomedich-274	7	31	healthcare	healthcare	PROPN
biomedich-274	7	32	system	system	NOUN
biomedich-274	7	33	.	.	PUNCT
biomedich-274	8	1	humongous	humongous	ADJ
biomedich-274	8	2	efforts	effort	NOUN
biomedich-274	8	3	have	have	AUX
biomedich-274	8	4	been	be	AUX
biomedich-274	8	5	put	put	VERB
biomedich-274	8	6	in	in	ADP
biomedich-274	8	7	ascertaining	ascertain	VERB
biomedich-274	8	8	the	the	DET
biomedich-274	8	9	effective	effective	ADJ
biomedich-274	8	10	treatments	treatment	NOUN
biomedich-274	8	11	for	for	ADP
biomedich-274	8	12	attenuation	attenuation	NOUN
biomedich-274	8	13	of	of	ADP
biomedich-274	8	14	the	the	DET
biomedich-274	8	15	spread	spread	NOUN
biomedich-274	8	16	of	of	ADP
biomedich-274	8	17	corona	corona	NOUN
biomedich-274	8	18	virus	virus	NOUN
biomedich-274	8	19	disease	disease	NOUN
biomedich-274	8	20	(	(	PUNCT
biomedich-274	8	21	covid-19	covid-19	PROPN
biomedich-274	8	22	)	)	PUNCT
biomedich-274	8	23	pandemic	pandemic	NOUN
biomedich-274	8	24	.	.	PUNCT
biomedich-274	9	1	the	the	DET
biomedich-274	9	2	aim	aim	NOUN
biomedich-274	9	3	of	of	ADP
biomedich-274	9	4	this	this	DET
biomedich-274	9	5	research	research	NOUN
biomedich-274	9	6	study	study	NOUN
biomedich-274	9	7	is	be	AUX
biomedich-274	9	8	to	to	PART
biomedich-274	9	9	probe	probe	VERB
biomedich-274	9	10	the	the	DET
biomedich-274	9	11	potential	potential	ADJ
biomedich-274	9	12	inhibition	inhibition	NOUN
biomedich-274	9	13	of	of	ADP
biomedich-274	9	14	angiotensin	angiotensin	NOUN
biomedich-274	9	15	converting	convert	VERB
biomedich-274	9	16	enzyme	enzyme	NOUN
biomedich-274	9	17	2	2	NUM
biomedich-274	9	18	(	(	PUNCT
biomedich-274	9	19	ace2	ace2	NOUN
biomedich-274	9	20	)	)	PUNCT
biomedich-274	9	21	membrane	membrane	NOUN
biomedich-274	9	22	protein	protein	NOUN
biomedich-274	9	23	by	by	ADP
biomedich-274	9	24	well	well	ADV
biomedich-274	9	25	-	-	PUNCT
biomedich-274	9	26	known	know	VERB
biomedich-274	9	27	flavone	flavone	NOUN
biomedich-274	9	28	glycosides	glycoside	NOUN
biomedich-274	9	29	,	,	PUNCT
biomedich-274	9	30	hence	hence	ADV
biomedich-274	9	31	preventing	prevent	VERB
biomedich-274	9	32	the	the	DET
biomedich-274	9	33	binding	binding	NOUN
biomedich-274	9	34	of	of	ADP
biomedich-274	9	35	spike	spike	ADJ
biomedich-274	9	36	proteins	protein	NOUN
biomedich-274	9	37	with	with	ADP
biomedich-274	9	38	ace2	ace2	NOUN
biomedich-274	9	39	and	and	CCONJ
biomedich-274	9	40	subsequent	subsequent	ADJ
biomedich-274	9	41	prevention	prevention	NOUN
biomedich-274	9	42	of	of	ADP
biomedich-274	9	43	entry	entry	NOUN
biomedich-274	9	44	of	of	ADP
biomedich-274	9	45	sarscov-2	sarscov-2	NUM
biomedich-274	9	46	inside	inside	ADP
biomedich-274	9	47	the	the	DET
biomedich-274	9	48	cells	cell	NOUN
biomedich-274	9	49	.	.	PUNCT
biomedich-274	10	1	the	the	DET
biomedich-274	10	2	molecular	molecular	ADJ
biomedich-274	10	3	docking	docking	NOUN
biomedich-274	10	4	analysis	analysis	NOUN
biomedich-274	10	5	,	,	PUNCT
biomedich-274	10	6	for	for	SCONJ
biomedich-274	10	7	total	total	ADJ
biomedich-274	10	8	ten	ten	NUM
biomedich-274	10	9	flavone	flavone	NOUN
biomedich-274	10	10	glycosides	glycoside	NOUN
biomedich-274	10	11	was	be	AUX
biomedich-274	10	12	carried	carry	VERB
biomedich-274	10	13	out	out	ADP
biomedich-274	10	14	,	,	PUNCT
biomedich-274	10	15	that	that	PRON
biomedich-274	10	16	laid	lay	VERB
biomedich-274	10	17	out	out	ADP
biomedich-274	10	18	propitious	propitious	ADJ
biomedich-274	10	19	results	result	NOUN
biomedich-274	10	20	in	in	ADP
biomedich-274	10	21	terms	term	NOUN
biomedich-274	10	22	of	of	ADP
biomedich-274	10	23	binding	bind	VERB
biomedich-274	10	24	energies	energy	NOUN
biomedich-274	10	25	towards	towards	ADP
biomedich-274	10	26	the	the	DET
biomedich-274	10	27	active	active	ADJ
biomedich-274	10	28	residues	residue	NOUN
biomedich-274	10	29	of	of	ADP
biomedich-274	10	30	ace2	ace2	NOUN
biomedich-274	10	31	protein	protein	NOUN
biomedich-274	10	32	with	with	ADP
biomedich-274	10	33	a	a	DET
biomedich-274	10	34	range	range	NOUN
biomedich-274	10	35	of	of	ADP
biomedich-274	10	36	-9.3	-9.3	PROPN
biomedich-274	10	37	to	to	PART
biomedich-274	10	38	-7.1	-7.1	PUNCT
biomedich-274	10	39	kcal	kcal	PROPN
biomedich-274	10	40	/	/	SYM
biomedich-274	10	41	mol	mol	PROPN
biomedich-274	10	42	.	.	PUNCT
biomedich-274	11	1	the	the	DET
biomedich-274	11	2	molecular	molecular	ADJ
biomedich-274	11	3	dynamics	dynamic	NOUN
biomedich-274	11	4	simulation	simulation	NOUN
biomedich-274	11	5	also	also	ADV
biomedich-274	11	6	yielded	yield	VERB
biomedich-274	11	7	promising	promising	ADJ
biomedich-274	11	8	outcomes	outcome	NOUN
biomedich-274	11	9	.	.	PUNCT
biomedich-274	12	1	the	the	DET
biomedich-274	12	2	in	in	ADP
biomedich-274	12	3	-	-	PUNCT
biomedich-274	12	4	silico	silico	NOUN
biomedich-274	12	5	toxicity	toxicity	NOUN
biomedich-274	12	6	analysis	analysis	NOUN
biomedich-274	12	7	of	of	ADP
biomedich-274	12	8	all	all	DET
biomedich-274	12	9	the	the	DET
biomedich-274	12	10	potential	potential	ADJ
biomedich-274	12	11	drug	drug	NOUN
biomedich-274	12	12	candidates	candidate	NOUN
biomedich-274	12	13	was	be	AUX
biomedich-274	12	14	carried	carry	VERB
biomedich-274	12	15	out	out	ADP
biomedich-274	12	16	that	that	PRON
biomedich-274	12	17	revealed	reveal	VERB
biomedich-274	12	18	that	that	SCONJ
biomedich-274	12	19	all	all	DET
biomedich-274	12	20	the	the	DET
biomedich-274	12	21	compounds	compound	NOUN
biomedich-274	12	22	were	be	AUX
biomedich-274	12	23	non	non	ADJ
biomedich-274	12	24	-	-	ADJ
biomedich-274	12	25	toxic	toxic	ADJ
biomedich-274	12	26	and	and	CCONJ
biomedich-274	12	27	safe	safe	ADJ
biomedich-274	12	28	.	.	PUNCT
biomedich-274	13	1	studies	study	NOUN
biomedich-274	13	2	may	may	AUX
biomedich-274	13	3	be	be	AUX
biomedich-274	13	4	required	require	VERB
biomedich-274	13	5	for	for	ADP
biomedich-274	13	6	optimum	optimum	ADJ
biomedich-274	13	7	formulation	formulation	NOUN
biomedich-274	13	8	development	development	NOUN
biomedich-274	13	9	using	use	VERB
biomedich-274	13	10	these	these	DET
biomedich-274	13	11	compounds	compound	NOUN
biomedich-274	13	12	as	as	ADP
biomedich-274	13	13	a	a	DET
biomedich-274	13	14	part	part	NOUN
biomedich-274	13	15	of	of	ADP
biomedich-274	13	16	drug	drug	NOUN
biomedich-274	13	17	discovery	discovery	NOUN
biomedich-274	13	18	and	and	CCONJ
biomedich-274	13	19	development	development	NOUN
biomedich-274	13	20	phenomenon	phenomenon	NOUN
biomedich-274	13	21	.	.	PUNCT
biomedich-274	14	1	this	this	DET
biomedich-274	14	2	study	study	NOUN
biomedich-274	14	3	may	may	AUX
biomedich-274	14	4	play	play	VERB
biomedich-274	14	5	a	a	DET
biomedich-274	14	6	vital	vital	ADJ
biomedich-274	14	7	part	part	NOUN
biomedich-274	14	8	in	in	ADP
biomedich-274	14	9	exploration	exploration	NOUN
biomedich-274	14	10	of	of	ADP
biomedich-274	14	11	natural	natural	ADJ
biomedich-274	14	12	compounds	compound	NOUN
biomedich-274	14	13	in	in	ADP
biomedich-274	14	14	pharmacotherapy	pharmacotherapy	NOUN
biomedich-274	14	15	of	of	ADP
biomedich-274	14	16	covid-19	covid-19	PROPN
biomedich-274	14	17	.	.	PUNCT
biomedich-274	15	1	keywords	keyword	NOUN
biomedich-274	15	2	:	:	PUNCT
biomedich-274	15	3	ace2	ace2	NOUN
biomedich-274	15	4	membrane	membrane	NOUN
biomedich-274	15	5	protein	protein	NOUN
biomedich-274	15	6	;	;	PUNCT
biomedich-274	15	7	covid-19	covid-19	PROPN
biomedich-274	15	8	;	;	PUNCT
biomedich-274	15	9	flavone	flavone	NOUN
biomedich-274	15	10	glycosides	glycoside	NOUN
biomedich-274	15	11	;	;	PUNCT
biomedich-274	15	12	molecular	molecular	ADJ
biomedich-274	15	13	docking	docking	NOUN
biomedich-274	15	14	analysis	analysis	NOUN
biomedich-274	15	15	;	;	PUNCT
biomedich-274	15	16	sarscov-2	sarscov-2	NUM
biomedich-274	15	17	;	;	PUNCT
biomedich-274	15	18	spike	spike	ADJ
biomedich-274	15	19	proteins	protein	NOUN
biomedich-274	15	20	.	.	PUNCT
biomedich-274	16	1	abbreviations	abbreviation	NOUN
biomedich-274	16	2	:	:	PUNCT
biomedich-274	16	3	sarscov-2	sarscov-2	NUM
biomedich-274	16	4	:	:	PUNCT
biomedich-274	16	5	severe	severe	ADJ
biomedich-274	16	6	acute	acute	ADJ
biomedich-274	16	7	respiratory	respiratory	ADJ
biomedich-274	16	8	syndrome	syndrome	NOUN
biomedich-274	16	9	coronavirus	coronavirus	NOUN
biomedich-274	16	10	2	2	NUM
biomedich-274	16	11	covid-19	covid-19	PROPN
biomedich-274	16	12	:	:	PUNCT
biomedich-274	16	13	corona	corona	NOUN
biomedich-274	16	14	virus	virus	NOUN
biomedich-274	16	15	disease	disease	NOUN
biomedich-274	16	16	ace2	ace2	PROPN
biomedich-274	16	17	:	:	PUNCT
biomedich-274	16	18	angiotensin	angiotensin	NOUN
biomedich-274	16	19	converting	convert	VERB
biomedich-274	16	20	enzyme	enzyme	NOUN
biomedich-274	16	21	2	2	NUM
biomedich-274	16	22	ssrna	ssrna	NOUN
biomedich-274	16	23	:	:	PUNCT
biomedich-274	16	24	single	single	ADJ
biomedich-274	16	25	stranded	strand	VERB
biomedich-274	16	26	ribonucleic	ribonucleic	ADJ
biomedich-274	16	27	acid	acid	NOUN
biomedich-274	16	28	prrar	prrar	NOUN
biomedich-274	16	29	:	:	PUNCT
biomedich-274	16	30	furin	furin	NOUN
biomedich-274	16	31	cleavage	cleavage	NOUN
biomedich-274	16	32	site	site	NOUN
biomedich-274	16	33	in	in	ADP
biomedich-274	16	34	spike	spike	ADJ
biomedich-274	16	35	protein	protein	NOUN
biomedich-274	16	36	tmprss2	tmprss2	NOUN
biomedich-274	16	37	:	:	PUNCT
biomedich-274	16	38	transmembrane	transmembrane	ADJ
biomedich-274	16	39	serine	serine	NOUN
biomedich-274	16	40	protease	protease	NOUN
biomedich-274	16	41	2	2	NUM
biomedich-274	16	42	s	s	NOUN
biomedich-274	16	43	protein	protein	NOUN
biomedich-274	16	44	:	:	PUNCT
biomedich-274	16	45	spike	spike	ADJ
biomedich-274	16	46	protein	protein	NOUN
biomedich-274	16	47	s	s	PART
biomedich-274	16	48	cleavage	cleavage	NOUN
biomedich-274	16	49	:	:	PUNCT
biomedich-274	16	50	spike	spike	ADJ
biomedich-274	16	51	cleavage	cleavage	NOUN
biomedich-274	16	52	rbd	rbd	NOUN
biomedich-274	16	53	:	:	PUNCT
biomedich-274	16	54	receptor	receptor	NOUN
biomedich-274	16	55	binding	bind	VERB
biomedich-274	16	56	domain	domain	NOUN
biomedich-274	16	57	pdb	pdb	NOUN
biomedich-274	16	58	:	:	PUNCT
biomedich-274	16	59	protein	protein	NOUN
biomedich-274	16	60	data	data	PROPN
biomedich-274	16	61	bank	bank	PROPN
biomedich-274	16	62	admet	admet	NOUN
biomedich-274	16	63	:	:	PUNCT
biomedich-274	16	64	absorption	absorption	NOUN
biomedich-274	16	65	,	,	PUNCT
biomedich-274	16	66	distribution	distribution	NOUN
biomedich-274	16	67	,	,	PUNCT
biomedich-274	16	68	metabolism	metabolism	NOUN
biomedich-274	16	69	,	,	PUNCT
biomedich-274	16	70	elimination	elimination	NOUN
biomedich-274	16	71	and	and	CCONJ
biomedich-274	16	72	toxicity	toxicity	NOUN
biomedich-274	16	73	profile	profile	NOUN
biomedich-274	16	74	introduction	introduction	NOUN
biomedich-274	16	75	the	the	DET
biomedich-274	16	76	severe	severe	ADJ
biomedich-274	16	77	acute	acute	ADJ
biomedich-274	16	78	respiratory	respiratory	ADJ
biomedich-274	16	79	syndrome	syndrome	NOUN
biomedich-274	16	80	coronavirus-2	coronavirus-2	NUM
biomedich-274	16	81	(	(	PUNCT
biomedich-274	16	82	sars	sar	NOUN
biomedich-274	16	83	-	-	PUNCT
biomedich-274	16	84	cov-2	cov-2	NOUN
biomedich-274	16	85	)	)	PUNCT
biomedich-274	16	86	emerged	emerge	VERB
biomedich-274	16	87	as	as	ADP
biomedich-274	16	88	the	the	DET
biomedich-274	16	89	most	most	ADV
biomedich-274	16	90	common	common	ADJ
biomedich-274	16	91	clinical	clinical	ADJ
biomedich-274	16	92	presentation	presentation	NOUN
biomedich-274	16	93	of	of	ADP
biomedich-274	16	94	severe	severe	ADJ
biomedich-274	16	95	covid-19	covid-19	PROPN
biomedich-274	16	96	(	(	PUNCT
biomedich-274	16	97	brosnahan	brosnahan	PROPN
biomedich-274	16	98	et	et	PROPN
biomedich-274	16	99	al	al	PROPN
biomedich-274	16	100	.	.	PROPN
biomedich-274	16	101	2020	2020	NUM
biomedich-274	16	102	)	)	PUNCT
biomedich-274	16	103	.	.	PUNCT
biomedich-274	17	1	coronavirus	coronavirus	NOUN
biomedich-274	17	2	disease	disease	NOUN
biomedich-274	17	3	started	start	VERB
biomedich-274	17	4	in	in	ADP
biomedich-274	17	5	wuhan	wuhan	PROPN
biomedich-274	17	6	,	,	PUNCT
biomedich-274	17	7	china	china	PROPN
biomedich-274	17	8	in	in	ADP
biomedich-274	17	9	late	late	ADJ
biomedich-274	17	10	2019	2019	NUM
biomedich-274	17	11	,	,	PUNCT
biomedich-274	17	12	spreading	spread	VERB
biomedich-274	17	13	worldwide	worldwide	ADV
biomedich-274	17	14	,	,	PUNCT
biomedich-274	17	15	affecting	affect	VERB
biomedich-274	17	16	612	612	NUM
biomedich-274	17	17	million	million	NUM
biomedich-274	17	18	people	people	NOUN
biomedich-274	17	19	and	and	CCONJ
biomedich-274	17	20	total	total	ADJ
biomedich-274	17	21	number	number	NOUN
biomedich-274	17	22	of	of	ADP
biomedich-274	17	23	deaths	death	NOUN
biomedich-274	17	24	exceeds	exceed	VERB
biomedich-274	17	25	6.53	6.53	NUM
biomedich-274	17	26	million	million	NUM
biomedich-274	17	27	as	as	ADP
biomedich-274	17	28	of	of	ADP
biomedich-274	17	29	september	september	PROPN
biomedich-274	17	30	2022	2022	NUM
biomedich-274	17	31	as	as	ADP
biomedich-274	17	32	per	per	ADP
biomedich-274	17	33	statistics	statistic	NOUN
biomedich-274	17	34	of	of	ADP
biomedich-274	17	35	world	world	PROPN
biomedich-274	17	36	health	health	NOUN
biomedich-274	17	37	organization	organization	NOUN
biomedich-274	17	38	(	(	PUNCT
biomedich-274	17	39	who	who	PRON
biomedich-274	17	40	)	)	PUNCT
biomedich-274	17	41	(	(	PUNCT
biomedich-274	17	42	“	"	PUNCT
biomedich-274	17	43	who	who	PRON
biomedich-274	17	44	coronavirus	coronavirus	NOUN
biomedich-274	17	45	(	(	PUNCT
biomedich-274	17	46	covid-19	covid-19	PROPN
biomedich-274	17	47	)	)	PUNCT
biomedich-274	17	48	dashboard	dashboard	NOUN
biomedich-274	17	49	|	|	ADV
biomedich-274	17	50	who	who	PRON
biomedich-274	17	51	coronavirus	coronavirus	NOUN
biomedich-274	17	52	(	(	PUNCT
biomedich-274	17	53	covid-19	covid-19	PROPN
biomedich-274	17	54	)	)	PUNCT
biomedich-274	17	55	dashboard	dashboard	NOUN
biomedich-274	17	56	with	with	ADP
biomedich-274	17	57	vaccination	vaccination	NOUN
biomedich-274	17	58	data	datum	NOUN
biomedich-274	17	59	”	"	PUNCT
biomedich-274	17	60	n.d	n.d	PROPN
biomedich-274	17	61	.	.	PROPN
biomedich-274	17	62	)	)	PUNCT
biomedich-274	17	63	.	.	PUNCT
biomedich-274	18	1	the	the	DET
biomedich-274	18	2	advent	advent	NOUN
biomedich-274	18	3	of	of	ADP
biomedich-274	18	4	covid-19	covid-19	PROPN
biomedich-274	18	5	created	create	VERB
biomedich-274	18	6	serious	serious	ADJ
biomedich-274	18	7	crisis	crisis	NOUN
biomedich-274	18	8	in	in	ADP
biomedich-274	18	9	health	health	NOUN
biomedich-274	18	10	sector	sector	NOUN
biomedich-274	18	11	,	,	PUNCT
biomedich-274	18	12	leaving	leave	VERB
biomedich-274	18	13	behind	behind	ADP
biomedich-274	18	14	huge	huge	ADJ
biomedich-274	18	15	gaps	gap	NOUN
biomedich-274	18	16	in	in	ADP
biomedich-274	18	17	the	the	DET
biomedich-274	18	18	field	field	NOUN
biomedich-274	18	19	of	of	ADP
biomedich-274	18	20	disease	disease	NOUN
biomedich-274	18	21	control	control	NOUN
biomedich-274	18	22	and	and	CCONJ
biomedich-274	18	23	prevention	prevention	NOUN
biomedich-274	18	24	,	,	PUNCT
biomedich-274	18	25	that	that	PRON
biomedich-274	18	26	could	could	AUX
biomedich-274	18	27	be	be	AUX
biomedich-274	18	28	bridged	bridge	VERB
biomedich-274	18	29	through	through	ADP
biomedich-274	18	30	new	new	ADJ
biomedich-274	18	31	research	research	NOUN
biomedich-274	18	32	and	and	CCONJ
biomedich-274	18	33	investigations	investigation	NOUN
biomedich-274	18	34	.	.	PUNCT
biomedich-274	19	1	the	the	DET
biomedich-274	19	2	genome	genome	NOUN
biomedich-274	19	3	of	of	ADP
biomedich-274	19	4	covid-19	covid-19	PROPN
biomedich-274	19	5	had	have	AUX
biomedich-274	19	6	been	be	AUX
biomedich-274	19	7	the	the	DET
biomedich-274	19	8	most	most	ADV
biomedich-274	19	9	noteworthy	noteworthy	ADJ
biomedich-274	19	10	in	in	ADP
biomedich-274	19	11	the	the	DET
biomedich-274	19	12	ongoing	ongoing	ADJ
biomedich-274	19	13	research	research	NOUN
biomedich-274	19	14	on	on	ADP
biomedich-274	19	15	sarscov-2	sarscov-2	NUM
biomedich-274	19	16	.	.	PUNCT
biomedich-274	20	1	it	it	PRON
biomedich-274	20	2	is	be	AUX
biomedich-274	20	3	a	a	DET
biomedich-274	20	4	positive	positive	ADJ
biomedich-274	20	5	sense	sense	NOUN
biomedich-274	20	6	single	single	ADV
biomedich-274	20	7	-	-	PUNCT
biomedich-274	20	8	stranded	strand	VERB
biomedich-274	20	9	rna	rna	NOUN
biomedich-274	20	10	(	(	PUNCT
biomedich-274	20	11	+	+	NOUN
biomedich-274	20	12	ssrna	ssrna	NOUN
biomedich-274	20	13	)	)	PUNCT
biomedich-274	20	14	and	and	CCONJ
biomedich-274	20	15	hence	hence	ADV
biomedich-274	20	16	tends	tend	VERB
biomedich-274	20	17	to	to	PART
biomedich-274	20	18	replicate	replicate	VERB
biomedich-274	20	19	in	in	ADP
biomedich-274	20	20	a	a	DET
biomedich-274	20	21	swift	swift	ADJ
biomedich-274	20	22	way	way	NOUN
biomedich-274	20	23	within	within	ADP
biomedich-274	20	24	the	the	DET
biomedich-274	20	25	host	host	NOUN
biomedich-274	20	26	cell	cell	NOUN
biomedich-274	20	27	.	.	PUNCT
biomedich-274	21	1	the	the	DET
biomedich-274	21	2	genetic	genetic	ADJ
biomedich-274	21	3	material	material	NOUN
biomedich-274	21	4	of	of	ADP
biomedich-274	21	5	the	the	DET
biomedich-274	21	6	virus	virus	NOUN
biomedich-274	21	7	encodes	encode	NOUN
biomedich-274	21	8	for	for	ADP
biomedich-274	21	9	many	many	ADJ
biomedich-274	21	10	nonstructural	nonstructural	ADJ
biomedich-274	21	11	proteins	protein	NOUN
biomedich-274	21	12	(	(	PUNCT
biomedich-274	21	13	nsps	nsps	NOUN
biomedich-274	21	14	)	)	PUNCT
biomedich-274	21	15	that	that	PRON
biomedich-274	21	16	implement	implement	VERB
biomedich-274	21	17	enormous	enormous	ADJ
biomedich-274	21	18	functions	function	NOUN
biomedich-274	21	19	for	for	ADP
biomedich-274	21	20	virus	virus	NOUN
biomedich-274	21	21	such	such	ADJ
biomedich-274	21	22	as	as	ADP
biomedich-274	21	23	taking	take	VERB
biomedich-274	21	24	the	the	DET
biomedich-274	21	25	control	control	NOUN
biomedich-274	21	26	the	the	DET
biomedich-274	21	27	host	host	NOUN
biomedich-274	21	28	biosynthetic	biosynthetic	ADJ
biomedich-274	21	29	machinery	machinery	NOUN
biomedich-274	21	30	,	,	PUNCT
biomedich-274	21	31	viral	viral	ADJ
biomedich-274	21	32	replication	replication	NOUN
biomedich-274	21	33	,	,	PUNCT
biomedich-274	21	34	viral	viral	ADJ
biomedich-274	21	35	protein	protein	NOUN
biomedich-274	21	36	processing	processing	NOUN
biomedich-274	21	37	etc	etc	X
biomedich-274	21	38	.	.	PUNCT
biomedich-274	22	1	the	the	DET
biomedich-274	22	2	function	function	NOUN
biomedich-274	22	3	of	of	ADP
biomedich-274	22	4	some	some	DET
biomedich-274	22	5	nsps	nsps	NOUN
biomedich-274	22	6	is	be	AUX
biomedich-274	22	7	still	still	ADV
biomedich-274	22	8	unknown	unknown	ADJ
biomedich-274	22	9	.	.	PUNCT
biomedich-274	23	1	the	the	DET
biomedich-274	23	2	structural	structural	ADJ
biomedich-274	23	3	genes	gene	NOUN
biomedich-274	23	4	of	of	ADP
biomedich-274	23	5	this	this	DET
biomedich-274	23	6	virus	virus	NOUN
biomedich-274	23	7	encode	encode	VERB
biomedich-274	23	8	for	for	ADP
biomedich-274	23	9	the	the	DET
biomedich-274	23	10	structural	structural	ADJ
biomedich-274	23	11	proteins	protein	NOUN
biomedich-274	23	12	,	,	PUNCT
biomedich-274	23	13	which	which	PRON
biomedich-274	23	14	include	include	VERB
biomedich-274	23	15	spike	spike	PROPN
biomedich-274	23	16	(	(	PUNCT
biomedich-274	23	17	s	s	NOUN
biomedich-274	23	18	)	)	PUNCT
biomedich-274	23	19	,	,	PUNCT
biomedich-274	23	20	membrane	membrane	NOUN
biomedich-274	23	21	(	(	PUNCT
biomedich-274	23	22	m	m	NOUN
biomedich-274	23	23	)	)	PUNCT
biomedich-274	23	24	,	,	PUNCT
biomedich-274	23	25	envelope	envelope	NOUN
biomedich-274	23	26	(	(	PUNCT
biomedich-274	23	27	e	e	NOUN
biomedich-274	23	28	)	)	PUNCT
biomedich-274	23	29	,	,	PUNCT
biomedich-274	23	30	and	and	CCONJ
biomedich-274	23	31	nucleocapsid	nucleocapsid	ADJ
biomedich-274	23	32	(	(	PUNCT
biomedich-274	23	33	n	n	CCONJ
biomedich-274	23	34	)	)	PUNCT
biomedich-274	23	35	proteins	protein	NOUN
biomedich-274	23	36	,	,	PUNCT
biomedich-274	23	37	having	have	VERB
biomedich-274	23	38	a	a	DET
biomedich-274	23	39	wide	wide	ADJ
biomedich-274	23	40	spectrum	spectrum	NOUN
biomedich-274	23	41	of	of	ADP
biomedich-274	23	42	functions	function	NOUN
biomedich-274	23	43	in	in	ADP
biomedich-274	23	44	https://doi.org/10.14421/biomedich.2023.121.97-108	https://doi.org/10.14421/biomedich.2023.121.97-108	ADP
biomedich-274	23	45	98	98	NUM
biomedich-274	23	46	biology	biology	NOUN
biomedich-274	23	47	,	,	PUNCT
biomedich-274	23	48	medicine	medicine	NOUN
biomedich-274	23	49	,	,	PUNCT
biomedich-274	23	50	&	&	CCONJ
biomedich-274	23	51	natural	natural	ADJ
biomedich-274	23	52	product	product	NOUN
biomedich-274	23	53	chemistry	chemistry	NOUN
biomedich-274	23	54	12	12	NUM
biomedich-274	23	55	(	(	PUNCT
biomedich-274	23	56	1	1	NUM
biomedich-274	23	57	)	)	PUNCT
biomedich-274	23	58	,	,	PUNCT
biomedich-274	23	59	2023	2023	NUM
biomedich-274	23	60	:	:	PUNCT
biomedich-274	23	61	97	97	NUM
biomedich-274	23	62	-	-	SYM
biomedich-274	23	63	108	108	NUM
biomedich-274	23	64	characterizing	characterize	VERB
biomedich-274	23	65	the	the	DET
biomedich-274	23	66	entry	entry	NOUN
biomedich-274	23	67	and	and	CCONJ
biomedich-274	23	68	pathogenicity	pathogenicity	NOUN
biomedich-274	23	69	of	of	ADP
biomedich-274	23	70	the	the	DET
biomedich-274	23	71	viral	viral	ADJ
biomedich-274	23	72	particle	particle	NOUN
biomedich-274	23	73	in	in	ADP
biomedich-274	23	74	the	the	DET
biomedich-274	23	75	host	host	NOUN
biomedich-274	23	76	cell	cell	NOUN
biomedich-274	23	77	.	.	PUNCT
biomedich-274	24	1	the	the	DET
biomedich-274	24	2	homotrimers	homotrimer	NOUN
biomedich-274	24	3	of	of	ADP
biomedich-274	24	4	s	s	NOUN
biomedich-274	24	5	proteins	protein	NOUN
biomedich-274	24	6	make	make	VERB
biomedich-274	24	7	up	up	ADP
biomedich-274	24	8	the	the	DET
biomedich-274	24	9	spikes	spike	NOUN
biomedich-274	24	10	on	on	ADP
biomedich-274	24	11	the	the	DET
biomedich-274	24	12	surface	surface	NOUN
biomedich-274	24	13	of	of	ADP
biomedich-274	24	14	viral	viral	ADJ
biomedich-274	24	15	particle	particle	NOUN
biomedich-274	24	16	and	and	CCONJ
biomedich-274	24	17	they	they	PRON
biomedich-274	24	18	are	be	AUX
biomedich-274	24	19	involved	involve	VERB
biomedich-274	24	20	in	in	ADP
biomedich-274	24	21	the	the	DET
biomedich-274	24	22	attachment	attachment	NOUN
biomedich-274	24	23	to	to	ADP
biomedich-274	24	24	the	the	DET
biomedich-274	24	25	host	host	NOUN
biomedich-274	24	26	cell	cell	NOUN
biomedich-274	24	27	receptors	receptor	NOUN
biomedich-274	24	28	.	.	PUNCT
biomedich-274	25	1	spike	spike	ADJ
biomedich-274	25	2	proteins	protein	NOUN
biomedich-274	25	3	hold	hold	VERB
biomedich-274	25	4	prime	prime	ADJ
biomedich-274	25	5	importance	importance	NOUN
biomedich-274	25	6	in	in	ADP
biomedich-274	25	7	relation	relation	NOUN
biomedich-274	25	8	to	to	ADP
biomedich-274	25	9	the	the	DET
biomedich-274	25	10	ace2	ace2	PROPN
biomedich-274	25	11	proteins	protein	NOUN
biomedich-274	25	12	to	to	PART
biomedich-274	25	13	which	which	PRON
biomedich-274	25	14	they	they	PRON
biomedich-274	25	15	bind	bind	VERB
biomedich-274	25	16	and	and	CCONJ
biomedich-274	25	17	provoke	provoke	VERB
biomedich-274	25	18	the	the	DET
biomedich-274	25	19	infective	infective	ADJ
biomedich-274	25	20	cascade	cascade	NOUN
biomedich-274	25	21	of	of	ADP
biomedich-274	25	22	covid-19	covid-19	PROPN
biomedich-274	25	23	(	(	PUNCT
biomedich-274	25	24	chen	chen	PROPN
biomedich-274	25	25	,	,	PUNCT
biomedich-274	25	26	liu	liu	PROPN
biomedich-274	25	27	,	,	PUNCT
biomedich-274	25	28	and	and	CCONJ
biomedich-274	25	29	guo	guo	PROPN
biomedich-274	25	30	2020	2020	NUM
biomedich-274	25	31	)	)	PUNCT
biomedich-274	25	32	.	.	PUNCT
biomedich-274	26	1	in	in	ADP
biomedich-274	26	2	host	host	NOUN
biomedich-274	26	3	cells	cell	NOUN
biomedich-274	26	4	,	,	PUNCT
biomedich-274	26	5	spike	spike	ADJ
biomedich-274	26	6	protein	protein	NOUN
biomedich-274	26	7	(	(	PUNCT
biomedich-274	26	8	s	s	NOUN
biomedich-274	26	9	protein	protein	NOUN
biomedich-274	26	10	)	)	PUNCT
biomedich-274	26	11	is	be	AUX
biomedich-274	26	12	cleaved	cleave	VERB
biomedich-274	26	13	at	at	ADP
biomedich-274	26	14	the	the	DET
biomedich-274	26	15	furin	furin	NOUN
biomedich-274	26	16	cleavage	cleavage	NOUN
biomedich-274	26	17	site	site	NOUN
biomedich-274	26	18	i.e.	i.e.	X
biomedich-274	26	19	prrar	prrar	NOUN
biomedich-274	26	20	motif	motif	NOUN
biomedich-274	26	21	by	by	ADP
biomedich-274	26	22	a	a	DET
biomedich-274	26	23	protease	protease	NOUN
biomedich-274	26	24	named	name	VERB
biomedich-274	26	25	furin	furin	NOUN
biomedich-274	26	26	into	into	ADP
biomedich-274	26	27	s1	s1	NOUN
biomedich-274	26	28	and	and	CCONJ
biomedich-274	26	29	s2	s2	NOUN
biomedich-274	26	30	to	to	PART
biomedich-274	26	31	form	form	VERB
biomedich-274	26	32	a	a	DET
biomedich-274	26	33	heterodimer	heterodimer	NOUN
biomedich-274	26	34	of	of	ADP
biomedich-274	26	35	s1	s1	PROPN
biomedich-274	26	36	/	/	SYM
biomedich-274	26	37	s2	s2	PROPN
biomedich-274	26	38	,	,	PUNCT
biomedich-274	26	39	which	which	PRON
biomedich-274	26	40	is	be	AUX
biomedich-274	26	41	finally	finally	ADV
biomedich-274	26	42	assembled	assemble	VERB
biomedich-274	26	43	in	in	ADP
biomedich-274	26	44	the	the	DET
biomedich-274	26	45	form	form	NOUN
biomedich-274	26	46	of	of	ADP
biomedich-274	26	47	the	the	DET
biomedich-274	26	48	trimeric	trimeric	ADJ
biomedich-274	26	49	spike	spike	ADJ
biomedich-274	26	50	protein	protein	NOUN
biomedich-274	26	51	complex	complex	NOUN
biomedich-274	26	52	.	.	PUNCT
biomedich-274	27	1	the	the	DET
biomedich-274	27	2	s2	s2	NOUN
biomedich-274	27	3	subunit	subunit	NOUN
biomedich-274	27	4	of	of	ADP
biomedich-274	27	5	this	this	DET
biomedich-274	27	6	complex	complex	NOUN
biomedich-274	27	7	is	be	AUX
biomedich-274	27	8	cleaved	cleave	VERB
biomedich-274	27	9	by	by	ADP
biomedich-274	27	10	host	host	NOUN
biomedich-274	27	11	proteases	protease	NOUN
biomedich-274	27	12	like	like	ADP
biomedich-274	27	13	transmembrane	transmembrane	ADJ
biomedich-274	27	14	protease	protease	NOUN
biomedich-274	27	15	serine	serine	NOUN
biomedich-274	27	16	2	2	NUM
biomedich-274	27	17	(	(	PUNCT
biomedich-274	27	18	tmprss2	tmprss2	ADV
biomedich-274	27	19	)	)	PUNCT
biomedich-274	27	20	to	to	PART
biomedich-274	27	21	uncover	uncover	VERB
biomedich-274	27	22	the	the	DET
biomedich-274	27	23	fusion	fusion	NOUN
biomedich-274	27	24	peptide	peptide	NOUN
biomedich-274	27	25	for	for	ADP
biomedich-274	27	26	membrane	membrane	NOUN
biomedich-274	27	27	fusion	fusion	NOUN
biomedich-274	27	28	of	of	ADP
biomedich-274	27	29	the	the	DET
biomedich-274	27	30	host	host	NOUN
biomedich-274	27	31	cell	cell	NOUN
biomedich-274	27	32	and	and	CCONJ
biomedich-274	27	33	virus	virus	NOUN
biomedich-274	27	34	(	(	PUNCT
biomedich-274	27	35	wu	wu	PROPN
biomedich-274	27	36	et	et	PROPN
biomedich-274	27	37	al	al	PROPN
biomedich-274	27	38	.	.	PROPN
biomedich-274	27	39	2022	2022	NUM
biomedich-274	27	40	)	)	PUNCT
biomedich-274	27	41	.	.	PUNCT
biomedich-274	28	1	s1	s1	NOUN
biomedich-274	28	2	is	be	AUX
biomedich-274	28	3	for	for	ADP
biomedich-274	28	4	binding	bind	VERB
biomedich-274	28	5	to	to	ADP
biomedich-274	28	6	the	the	DET
biomedich-274	28	7	host	host	NOUN
biomedich-274	28	8	cell	cell	NOUN
biomedich-274	28	9	receptor	receptor	NOUN
biomedich-274	28	10	angiotensin	angiotensin	NOUN
biomedich-274	28	11	-	-	PUNCT
biomedich-274	28	12	converting	convert	VERB
biomedich-274	28	13	enzyme	enzyme	NOUN
biomedich-274	28	14	2	2	NUM
biomedich-274	28	15	(	(	PUNCT
biomedich-274	28	16	ace2	ace2	PROPN
biomedich-274	28	17	)	)	PUNCT
biomedich-274	28	18	.	.	PUNCT
biomedich-274	29	1	it	it	PRON
biomedich-274	29	2	is	be	AUX
biomedich-274	29	3	v	v	ADV
biomedich-274	29	4	-	-	PUNCT
biomedich-274	29	5	shaped	shape	VERB
biomedich-274	29	6	and	and	CCONJ
biomedich-274	29	7	the	the	DET
biomedich-274	29	8	second	second	ADJ
biomedich-274	29	9	one	one	NOUN
biomedich-274	29	10	(	(	PUNCT
biomedich-274	29	11	s2	s2	NOUN
biomedich-274	29	12	subunit	subunit	NOUN
biomedich-274	29	13	)	)	PUNCT
biomedich-274	29	14	for	for	ADP
biomedich-274	29	15	fusion	fusion	NOUN
biomedich-274	29	16	of	of	ADP
biomedich-274	29	17	the	the	DET
biomedich-274	29	18	viral	viral	ADJ
biomedich-274	29	19	and	and	CCONJ
biomedich-274	29	20	host	host	NOUN
biomedich-274	29	21	cell	cell	NOUN
biomedich-274	29	22	membranes	membrane	NOUN
biomedich-274	29	23	(	(	PUNCT
biomedich-274	29	24	sternberg	sternberg	PROPN
biomedich-274	29	25	and	and	CCONJ
biomedich-274	29	26	naujokat	naujokat	NOUN
biomedich-274	29	27	2020	2020	NUM
biomedich-274	29	28	)	)	PUNCT
biomedich-274	29	29	.	.	PUNCT
biomedich-274	30	1	ace2	ace2	PROPN
biomedich-274	30	2	and	and	CCONJ
biomedich-274	30	3	tmprss2	tmprss2	PRON
biomedich-274	30	4	are	be	AUX
biomedich-274	30	5	abundantly	abundantly	ADV
biomedich-274	30	6	present	present	ADJ
biomedich-274	30	7	in	in	ADP
biomedich-274	30	8	the	the	DET
biomedich-274	30	9	airways	airway	NOUN
biomedich-274	30	10	,	,	PUNCT
biomedich-274	30	11	arteries	artery	NOUN
biomedich-274	30	12	,	,	PUNCT
biomedich-274	30	13	nasal	nasal	NOUN
biomedich-274	30	14	and	and	CCONJ
biomedich-274	30	15	oral	oral	ADJ
biomedich-274	30	16	mucosa	mucosa	NOUN
biomedich-274	30	17	,	,	PUNCT
biomedich-274	30	18	kidneys	kidney	NOUN
biomedich-274	30	19	,	,	PUNCT
biomedich-274	30	20	the	the	DET
biomedich-274	30	21	intestine	intestine	NOUN
biomedich-274	30	22	,	,	PUNCT
biomedich-274	30	23	most	most	ADV
biomedich-274	30	24	profusely	profusely	ADV
biomedich-274	30	25	expressed	express	VERB
biomedich-274	30	26	on	on	ADP
biomedich-274	30	27	epithelial	epithelial	ADJ
biomedich-274	30	28	cells	cell	NOUN
biomedich-274	30	29	of	of	ADP
biomedich-274	30	30	the	the	DET
biomedich-274	30	31	respiratory	respiratory	ADJ
biomedich-274	30	32	tract	tract	NOUN
biomedich-274	30	33	i.e.	i.e.	X
biomedich-274	30	34	type	type	NOUN
biomedich-274	30	35	ii	ii	PROPN
biomedich-274	30	36	pneumocytes	pneumocyte	NOUN
biomedich-274	30	37	that	that	PRON
biomedich-274	30	38	are	be	AUX
biomedich-274	30	39	the	the	DET
biomedich-274	30	40	cells	cell	NOUN
biomedich-274	30	41	responsible	responsible	ADJ
biomedich-274	30	42	for	for	ADP
biomedich-274	30	43	secreting	secrete	VERB
biomedich-274	30	44	surfactant	surfactant	NOUN
biomedich-274	30	45	to	to	PART
biomedich-274	30	46	lessen	lessen	VERB
biomedich-274	30	47	the	the	DET
biomedich-274	30	48	surface	surface	NOUN
biomedich-274	30	49	tension	tension	NOUN
biomedich-274	30	50	and	and	CCONJ
biomedich-274	30	51	prevent	prevent	VERB
biomedich-274	30	52	lung	lung	NOUN
biomedich-274	30	53	collapse	collapse	NOUN
biomedich-274	30	54	(	(	PUNCT
biomedich-274	30	55	sternberg	sternberg	PROPN
biomedich-274	30	56	and	and	CCONJ
biomedich-274	30	57	naujokat	naujokat	NOUN
biomedich-274	30	58	2020	2020	NUM
biomedich-274	30	59	;	;	PUNCT
biomedich-274	30	60	akkız	akkız	NOUN
biomedich-274	30	61	2022	2022	NUM
biomedich-274	30	62	)	)	PUNCT
biomedich-274	30	63	.	.	PUNCT
biomedich-274	31	1	receptor	receptor	NOUN
biomedich-274	31	2	-	-	PUNCT
biomedich-274	31	3	binding	bind	VERB
biomedich-274	31	4	domain	domain	NOUN
biomedich-274	31	5	(	(	PUNCT
biomedich-274	31	6	rbd	rbd	NOUN
biomedich-274	31	7	)	)	PUNCT
biomedich-274	31	8	contains	contain	VERB
biomedich-274	31	9	a	a	DET
biomedich-274	31	10	receptor	receptor	NOUN
biomedich-274	31	11	binding	bind	VERB
biomedich-274	31	12	motif	motif	NOUN
biomedich-274	31	13	,	,	PUNCT
biomedich-274	31	14	which	which	PRON
biomedich-274	31	15	is	be	AUX
biomedich-274	31	16	the	the	DET
biomedich-274	31	17	necessary	necessary	ADJ
biomedich-274	31	18	for	for	ADP
biomedich-274	31	19	spike	spike	ADJ
biomedich-274	31	20	protein	protein	NOUN
biomedich-274	31	21	(	(	PUNCT
biomedich-274	31	22	s1	s1	NOUN
biomedich-274	31	23	)	)	PUNCT
biomedich-274	31	24	that	that	PRON
biomedich-274	31	25	binds	bind	VERB
biomedich-274	31	26	to	to	ADP
biomedich-274	31	27	the	the	DET
biomedich-274	31	28	outer	outer	ADJ
biomedich-274	31	29	surface	surface	NOUN
biomedich-274	31	30	of	of	ADP
biomedich-274	31	31	ace2	ace2	PROPN
biomedich-274	31	32	protein	protein	NOUN
biomedich-274	31	33	.	.	PUNCT
biomedich-274	32	1	tmprss2	tmprss2	PROPN
biomedich-274	32	2	cleaves	cleave	VERB
biomedich-274	32	3	a	a	DET
biomedich-274	32	4	part	part	NOUN
biomedich-274	32	5	of	of	ADP
biomedich-274	32	6	spike	spike	ADJ
biomedich-274	32	7	proteins	protein	NOUN
biomedich-274	32	8	and	and	CCONJ
biomedich-274	32	9	promote	promote	VERB
biomedich-274	32	10	the	the	DET
biomedich-274	32	11	adhesion	adhesion	NOUN
biomedich-274	32	12	of	of	ADP
biomedich-274	32	13	sars	sar	NOUN
biomedich-274	32	14	-	-	PUNCT
biomedich-274	32	15	cov-2	cov-2	NOUN
biomedich-274	32	16	s	s	PART
biomedich-274	32	17	protein	protein	NOUN
biomedich-274	32	18	to	to	PART
biomedich-274	32	19	get	get	VERB
biomedich-274	32	20	fuse	fuse	NOUN
biomedich-274	32	21	with	with	ADP
biomedich-274	32	22	host	host	NOUN
biomedich-274	32	23	cell	cell	NOUN
biomedich-274	32	24	membrane	membrane	NOUN
biomedich-274	32	25	as	as	SCONJ
biomedich-274	32	26	the	the	DET
biomedich-274	32	27	extended	extended	ADJ
biomedich-274	32	28	spike	spike	NOUN
biomedich-274	32	29	fosters	foster	VERB
biomedich-274	32	30	the	the	DET
biomedich-274	32	31	fusion	fusion	NOUN
biomedich-274	32	32	of	of	ADP
biomedich-274	32	33	viral	viral	ADJ
biomedich-274	32	34	and	and	CCONJ
biomedich-274	32	35	host	host	NOUN
biomedich-274	32	36	cell	cell	NOUN
biomedich-274	32	37	membrane	membrane	NOUN
biomedich-274	32	38	.	.	PUNCT
biomedich-274	33	1	subsequently	subsequently	ADV
biomedich-274	33	2	,	,	PUNCT
biomedich-274	33	3	many	many	ADJ
biomedich-274	33	4	hydrophobic	hydrophobic	NOUN
biomedich-274	33	5	amino	amino	NOUN
biomedich-274	33	6	acids	acid	NOUN
biomedich-274	33	7	are	be	AUX
biomedich-274	33	8	also	also	ADV
biomedich-274	33	9	generated	generate	VERB
biomedich-274	33	10	that	that	PRON
biomedich-274	33	11	get	get	AUX
biomedich-274	33	12	concealed	conceal	VERB
biomedich-274	33	13	in	in	ADP
biomedich-274	33	14	nearby	nearby	ADJ
biomedich-274	33	15	cell	cell	NOUN
biomedich-274	33	16	membrane	membrane	NOUN
biomedich-274	33	17	.	.	PUNCT
biomedich-274	34	1	the	the	DET
biomedich-274	34	2	virus	virus	NOUN
biomedich-274	34	3	enters	enter	VERB
biomedich-274	34	4	into	into	ADP
biomedich-274	34	5	the	the	DET
biomedich-274	34	6	cell	cell	NOUN
biomedich-274	34	7	and	and	CCONJ
biomedich-274	34	8	have	have	VERB
biomedich-274	34	9	a	a	DET
biomedich-274	34	10	first	first	ADJ
biomedich-274	34	11	encounter	encounter	NOUN
biomedich-274	34	12	with	with	ADP
biomedich-274	34	13	host	host	NOUN
biomedich-274	34	14	cell	cell	NOUN
biomedich-274	34	15	biosynthetic	biosynthetic	ADJ
biomedich-274	34	16	machinery	machinery	NOUN
biomedich-274	34	17	for	for	ADP
biomedich-274	34	18	translation	translation	NOUN
biomedich-274	34	19	of	of	ADP
biomedich-274	34	20	viral	viral	ADJ
biomedich-274	34	21	genetic	genetic	ADJ
biomedich-274	34	22	material	material	NOUN
biomedich-274	34	23	into	into	ADP
biomedich-274	34	24	viral	viral	ADJ
biomedich-274	34	25	proteins	protein	NOUN
biomedich-274	34	26	leading	lead	VERB
biomedich-274	34	27	to	to	ADP
biomedich-274	34	28	prompt	prompt	ADJ
biomedich-274	34	29	replication	replication	NOUN
biomedich-274	34	30	.	.	PUNCT
biomedich-274	35	1	cells	cell	NOUN
biomedich-274	35	2	that	that	PRON
biomedich-274	35	3	overexpress	overexpress	NOUN
biomedich-274	35	4	ace2	ace2	NOUN
biomedich-274	35	5	and	and	CCONJ
biomedich-274	35	6	tmprss2	tmprss2	PRON
biomedich-274	35	7	are	be	AUX
biomedich-274	35	8	more	more	ADV
biomedich-274	35	9	susceptible	susceptible	ADJ
biomedich-274	35	10	to	to	ADP
biomedich-274	35	11	sarscov-2	sarscov-2	NUM
biomedich-274	35	12	entry	entry	NOUN
biomedich-274	35	13	(	(	PUNCT
biomedich-274	35	14	akkız	akkız	NOUN
biomedich-274	35	15	2022	2022	NUM
biomedich-274	35	16	;	;	PUNCT
biomedich-274	35	17	ahmad	ahmad	PROPN
biomedich-274	35	18	et	et	PROPN
biomedich-274	35	19	al	al	PROPN
biomedich-274	35	20	.	.	PROPN
biomedich-274	35	21	2021	2021	NUM
biomedich-274	35	22	)	)	PUNCT
biomedich-274	35	23	.	.	PUNCT
biomedich-274	36	1	ace2	ace2	PROPN
biomedich-274	36	2	is	be	AUX
biomedich-274	36	3	a	a	DET
biomedich-274	36	4	membrane	membrane	NOUN
biomedich-274	36	5	-	-	PUNCT
biomedich-274	36	6	bound	bind	VERB
biomedich-274	36	7	carboxydipeptidase	carboxydipeptidase	NOUN
biomedich-274	36	8	protein	protein	NOUN
biomedich-274	36	9	.	.	PUNCT
biomedich-274	37	1	ace2	ace2	PROPN
biomedich-274	37	2	degrades	degrade	VERB
biomedich-274	37	3	angiotensin	angiotensin	NOUN
biomedich-274	37	4	ii	ii	PROPN
biomedich-274	37	5	to	to	PART
biomedich-274	37	6	generate	generate	VERB
biomedich-274	37	7	angiotensin	angiotensin	NOUN
biomedich-274	37	8	1	1	NUM
biomedich-274	37	9	-	-	SYM
biomedich-274	37	10	7	7	NUM
biomedich-274	37	11	,	,	PUNCT
biomedich-274	37	12	which	which	DET
biomedich-274	37	13	downregulates	downregulate	NOUN
biomedich-274	37	14	regulates	regulate	VERB
biomedich-274	37	15	a	a	DET
biomedich-274	37	16	variety	variety	NOUN
biomedich-274	37	17	of	of	ADP
biomedich-274	37	18	angiotensin	angiotensin	PROPN
biomedich-274	37	19	ii	ii	PROPN
biomedich-274	37	20	actions	action	NOUN
biomedich-274	37	21	mediated	mediate	VERB
biomedich-274	37	22	by	by	ADP
biomedich-274	37	23	counteracting	counteract	VERB
biomedich-274	37	24	effects	effect	NOUN
biomedich-274	37	25	against	against	ADP
biomedich-274	37	26	the	the	DET
biomedich-274	37	27	excessively	excessively	ADV
biomedich-274	37	28	activated	activate	VERB
biomedich-274	37	29	ace	ace	NOUN
biomedich-274	37	30	/	/	SYM
biomedich-274	37	31	angiotensin	angiotensin	NOUN
biomedich-274	37	32	ii	ii	PROPN
biomedich-274	37	33	/	/	SYM
biomedich-274	37	34	at1r	at1r	PROPN
biomedich-274	37	35	axis	axis	NOUN
biomedich-274	37	36	,	,	PUNCT
biomedich-274	37	37	angiotensin	angiotensin	NOUN
biomedich-274	37	38	ii	ii	PROPN
biomedich-274	37	39	type	type	NOUN
biomedich-274	37	40	1	1	NUM
biomedich-274	37	41	receptor	receptor	NOUN
biomedich-274	37	42	,	,	PUNCT
biomedich-274	37	43	as	as	SCONJ
biomedich-274	37	44	seen	see	VERB
biomedich-274	37	45	in	in	ADP
biomedich-274	37	46	hypertension	hypertension	NOUN
biomedich-274	37	47	,	,	PUNCT
biomedich-274	37	48	cardiac	cardiac	ADJ
biomedich-274	37	49	hypertrophy	hypertrophy	NOUN
biomedich-274	37	50	,	,	PUNCT
biomedich-274	37	51	heart	heart	NOUN
biomedich-274	37	52	failure	failure	NOUN
biomedich-274	37	53	,	,	PUNCT
biomedich-274	37	54	and	and	CCONJ
biomedich-274	37	55	some	some	DET
biomedich-274	37	56	cardiovascular	cardiovascular	ADJ
biomedich-274	37	57	disorders	disorder	NOUN
biomedich-274	37	58	.	.	PUNCT
biomedich-274	38	1	on	on	ADP
biomedich-274	38	2	the	the	DET
biomedich-274	38	3	other	other	ADJ
biomedich-274	38	4	hand	hand	NOUN
biomedich-274	38	5	,	,	PUNCT
biomedich-274	38	6	human	human	ADJ
biomedich-274	38	7	ace2	ace2	PROPN
biomedich-274	38	8	is	be	AUX
biomedich-274	38	9	a	a	DET
biomedich-274	38	10	known	know	VERB
biomedich-274	38	11	receptor	receptor	NOUN
biomedich-274	38	12	by	by	ADP
biomedich-274	38	13	which	which	PRON
biomedich-274	38	14	sars	sar	NOUN
biomedich-274	38	15	-	-	PUNCT
biomedich-274	38	16	cov-2	cov-2	PART
biomedich-274	38	17	particle	particle	NOUN
biomedich-274	38	18	enters	enter	VERB
biomedich-274	38	19	host	host	NOUN
biomedich-274	38	20	cells	cell	NOUN
biomedich-274	38	21	,	,	PUNCT
biomedich-274	38	22	by	by	ADP
biomedich-274	38	23	mutual	mutual	ADJ
biomedich-274	38	24	binding	binding	NOUN
biomedich-274	38	25	of	of	ADP
biomedich-274	38	26	the	the	DET
biomedich-274	38	27	spike	spike	ADJ
biomedich-274	38	28	protein	protein	NOUN
biomedich-274	38	29	of	of	ADP
biomedich-274	38	30	sar	sar	NOUN
biomedich-274	38	31	-	-	PUNCT
biomedich-274	38	32	cov-2	cov-2	PART
biomedich-274	38	33	and	and	CCONJ
biomedich-274	38	34	ace2	ace2	NOUN
biomedich-274	38	35	membrane	membrane	NOUN
biomedich-274	38	36	protein	protein	NOUN
biomedich-274	38	37	.	.	PUNCT
biomedich-274	39	1	this	this	PRON
biomedich-274	39	2	makes	make	VERB
biomedich-274	39	3	it	it	PRON
biomedich-274	39	4	a	a	DET
biomedich-274	39	5	critical	critical	ADJ
biomedich-274	39	6	site	site	NOUN
biomedich-274	39	7	for	for	ADP
biomedich-274	39	8	stopping	stop	VERB
biomedich-274	39	9	the	the	DET
biomedich-274	39	10	sarscov-2	sarscov-2	NUM
biomedich-274	39	11	to	to	PART
biomedich-274	39	12	enter	enter	VERB
biomedich-274	39	13	the	the	DET
biomedich-274	39	14	cells	cell	NOUN
biomedich-274	39	15	using	use	VERB
biomedich-274	39	16	various	various	ADJ
biomedich-274	39	17	ligands	ligand	NOUN
biomedich-274	39	18	.	.	PUNCT
biomedich-274	40	1	so	so	ADV
biomedich-274	40	2	,	,	PUNCT
biomedich-274	40	3	it	it	PRON
biomedich-274	40	4	is	be	AUX
biomedich-274	40	5	pivotal	pivotal	ADJ
biomedich-274	40	6	to	to	PART
biomedich-274	40	7	inhibit	inhibit	VERB
biomedich-274	40	8	ace2	ace2	NOUN
biomedich-274	40	9	,	,	PUNCT
biomedich-274	40	10	prevent	prevent	VERB
biomedich-274	40	11	viral	viral	ADJ
biomedich-274	40	12	genetic	genetic	ADJ
biomedich-274	40	13	material	material	NOUN
biomedich-274	40	14	entry	entry	NOUN
biomedich-274	40	15	into	into	ADP
biomedich-274	40	16	the	the	DET
biomedich-274	40	17	cell	cell	NOUN
biomedich-274	40	18	(	(	PUNCT
biomedich-274	40	19	kai	kai	PROPN
biomedich-274	40	20	and	and	CCONJ
biomedich-274	40	21	kai	kai	PROPN
biomedich-274	40	22	2020	2020	NUM
biomedich-274	40	23	)	)	PUNCT
biomedich-274	40	24	.	.	PUNCT
biomedich-274	41	1	the	the	DET
biomedich-274	41	2	figure	figure	NOUN
biomedich-274	41	3	1	1	NUM
biomedich-274	41	4	summarizes	summarize	VERB
biomedich-274	41	5	the	the	DET
biomedich-274	41	6	mechanism	mechanism	NOUN
biomedich-274	41	7	of	of	ADP
biomedich-274	41	8	the	the	DET
biomedich-274	41	9	whole	whole	ADJ
biomedich-274	41	10	process	process	NOUN
biomedich-274	41	11	.	.	PUNCT
biomedich-274	42	1	flavonoids	flavonoid	NOUN
biomedich-274	42	2	are	be	AUX
biomedich-274	42	3	the	the	DET
biomedich-274	42	4	polyphenolic	polyphenolic	ADJ
biomedich-274	42	5	compounds	compound	NOUN
biomedich-274	42	6	,	,	PUNCT
biomedich-274	42	7	very	very	ADV
biomedich-274	42	8	popular	popular	ADJ
biomedich-274	42	9	for	for	ADP
biomedich-274	42	10	the	the	DET
biomedich-274	42	11	extensive	extensive	ADJ
biomedich-274	42	12	pharmacological	pharmacological	ADJ
biomedich-274	42	13	effects	effect	NOUN
biomedich-274	42	14	they	they	PRON
biomedich-274	42	15	provide	provide	VERB
biomedich-274	42	16	such	such	ADJ
biomedich-274	42	17	as	as	ADP
biomedich-274	42	18	anti	anti	ADJ
biomedich-274	42	19	-	-	NOUN
biomedich-274	42	20	cancer	cancer	ADJ
biomedich-274	42	21	,	,	PUNCT
biomedich-274	42	22	anti	anti	ADJ
biomedich-274	42	23	-	-	ADJ
biomedich-274	42	24	inflammatory	inflammatory	ADJ
biomedich-274	42	25	,	,	PUNCT
biomedich-274	42	26	antioxidant	antioxidant	ADJ
biomedich-274	42	27	etc	etc	X
biomedich-274	42	28	.	.	X
biomedich-274	43	1	(	(	PUNCT
biomedich-274	43	2	panche	panche	PROPN
biomedich-274	43	3	,	,	PUNCT
biomedich-274	43	4	diwan	diwan	PROPN
biomedich-274	43	5	,	,	PUNCT
biomedich-274	43	6	and	and	CCONJ
biomedich-274	43	7	chandra	chandra	PROPN
biomedich-274	43	8	2016	2016	NUM
biomedich-274	43	9	)	)	PUNCT
biomedich-274	43	10	.	.	PUNCT
biomedich-274	44	1	flavones	flavone	NOUN
biomedich-274	44	2	are	be	AUX
biomedich-274	44	3	one	one	NUM
biomedich-274	44	4	of	of	ADP
biomedich-274	44	5	the	the	DET
biomedich-274	44	6	subclasses	subclass	NOUN
biomedich-274	44	7	of	of	ADP
biomedich-274	44	8	flavonoids	flavonoid	NOUN
biomedich-274	44	9	.	.	PUNCT
biomedich-274	45	1	the	the	DET
biomedich-274	45	2	glycosidic	glycosidic	ADJ
biomedich-274	45	3	linkages	linkage	NOUN
biomedich-274	45	4	at	at	ADP
biomedich-274	45	5	positions	position	NOUN
biomedich-274	45	6	3	3	NUM
biomedich-274	45	7	or	or	CCONJ
biomedich-274	45	8	7	7	NUM
biomedich-274	45	9	of	of	ADP
biomedich-274	45	10	flavones	flavone	NOUN
biomedich-274	45	11	leads	lead	VERB
biomedich-274	45	12	to	to	ADP
biomedich-274	45	13	formation	formation	NOUN
biomedich-274	45	14	of	of	ADP
biomedich-274	45	15	flavone	flavone	NOUN
biomedich-274	45	16	glycosides	glycoside	NOUN
biomedich-274	45	17	(	(	PUNCT
biomedich-274	45	18	kumar	kumar	PROPN
biomedich-274	45	19	and	and	CCONJ
biomedich-274	45	20	pandey	pandey	PROPN
biomedich-274	45	21	2013	2013	NUM
biomedich-274	45	22	)	)	PUNCT
biomedich-274	45	23	.	.	PUNCT
biomedich-274	46	1	besides	besides	SCONJ
biomedich-274	46	2	various	various	ADJ
biomedich-274	46	3	therapeutic	therapeutic	ADJ
biomedich-274	46	4	effects	effect	NOUN
biomedich-274	46	5	such	such	ADJ
biomedich-274	46	6	as	as	ADP
biomedich-274	46	7	antimicrobial	antimicrobial	ADJ
biomedich-274	46	8	,	,	PUNCT
biomedich-274	46	9	antidiabetic	antidiabetic	ADJ
biomedich-274	46	10	,	,	PUNCT
biomedich-274	46	11	hepatoprotective	hepatoprotective	NOUN
biomedich-274	46	12	,	,	PUNCT
biomedich-274	46	13	antitumor	antitumor	PROPN
biomedich-274	46	14	and	and	CCONJ
biomedich-274	46	15	immunomodulatory	immunomodulatory	ADJ
biomedich-274	46	16	effects	effect	NOUN
biomedich-274	46	17	(	(	PUNCT
biomedich-274	46	18	xiao	xiao	PROPN
biomedich-274	46	19	et	et	PROPN
biomedich-274	46	20	al	al	PROPN
biomedich-274	46	21	.	.	PROPN
biomedich-274	46	22	2016	2016	NUM
biomedich-274	46	23	)	)	PUNCT
biomedich-274	46	24	,	,	PUNCT
biomedich-274	46	25	flavone	flavone	NOUN
biomedich-274	46	26	glycosides	glycoside	NOUN
biomedich-274	46	27	have	have	AUX
biomedich-274	46	28	also	also	ADV
biomedich-274	46	29	been	be	AUX
biomedich-274	46	30	studied	study	VERB
biomedich-274	46	31	and	and	CCONJ
biomedich-274	46	32	reported	report	VERB
biomedich-274	46	33	for	for	ADP
biomedich-274	46	34	having	have	VERB
biomedich-274	46	35	antiviral	antiviral	ADJ
biomedich-274	46	36	effects	effect	NOUN
biomedich-274	46	37	against	against	ADP
biomedich-274	46	38	herpes	herpe	NOUN
biomedich-274	46	39	simplex	simplex	NOUN
biomedich-274	46	40	virus	virus	NOUN
biomedich-274	46	41	(	(	PUNCT
biomedich-274	46	42	hsv	hsv	PROPN
biomedich-274	46	43	)	)	PUNCT
biomedich-274	46	44	1	1	NUM
biomedich-274	46	45	and	and	CCONJ
biomedich-274	46	46	2	2	NUM
biomedich-274	46	47	(	(	PUNCT
biomedich-274	46	48	yarmolinsky	yarmolinsky	ADV
biomedich-274	46	49	et	et	PROPN
biomedich-274	46	50	al	al	PROPN
biomedich-274	46	51	.	.	PROPN
biomedich-274	46	52	2012	2012	NUM
biomedich-274	46	53	)	)	PUNCT
biomedich-274	46	54	.	.	PUNCT
biomedich-274	47	1	keeping	keep	VERB
biomedich-274	47	2	in	in	ADP
biomedich-274	47	3	view	view	NOUN
biomedich-274	47	4	that	that	DET
biomedich-274	47	5	fact	fact	NOUN
biomedich-274	47	6	that	that	SCONJ
biomedich-274	47	7	ace2	ace2	PROPN
biomedich-274	47	8	is	be	AUX
biomedich-274	47	9	a	a	DET
biomedich-274	47	10	potential	potential	ADJ
biomedich-274	47	11	target	target	NOUN
biomedich-274	47	12	,	,	PUNCT
biomedich-274	47	13	this	this	DET
biomedich-274	47	14	study	study	NOUN
biomedich-274	47	15	is	be	AUX
biomedich-274	47	16	going	go	VERB
biomedich-274	47	17	to	to	PART
biomedich-274	47	18	use	use	VERB
biomedich-274	47	19	molecular	molecular	ADJ
biomedich-274	47	20	docking	docking	NOUN
biomedich-274	47	21	as	as	ADP
biomedich-274	47	22	a	a	DET
biomedich-274	47	23	tool	tool	NOUN
biomedich-274	47	24	to	to	PART
biomedich-274	47	25	inquire	inquire	VERB
biomedich-274	47	26	regarding	regard	VERB
biomedich-274	47	27	the	the	DET
biomedich-274	47	28	activity	activity	NOUN
biomedich-274	47	29	of	of	ADP
biomedich-274	47	30	flavone	flavone	NOUN
biomedich-274	47	31	glycosides	glycoside	NOUN
biomedich-274	47	32	for	for	ADP
biomedich-274	47	33	inhibiting	inhibit	VERB
biomedich-274	47	34	ace2	ace2	NOUN
biomedich-274	47	35	and	and	CCONJ
biomedich-274	47	36	blocking	block	VERB
biomedich-274	47	37	the	the	DET
biomedich-274	47	38	entry	entry	NOUN
biomedich-274	47	39	of	of	ADP
biomedich-274	47	40	sarscov-2	sarscov-2	NUM
biomedich-274	47	41	into	into	ADP
biomedich-274	47	42	the	the	DET
biomedich-274	47	43	cell	cell	NOUN
biomedich-274	47	44	and	and	CCONJ
biomedich-274	47	45	arresting	arrest	VERB
biomedich-274	47	46	the	the	DET
biomedich-274	47	47	viral	viral	ADJ
biomedich-274	47	48	replication	replication	NOUN
biomedich-274	47	49	process	process	NOUN
biomedich-274	47	50	.	.	PUNCT
biomedich-274	48	1	figure	figure	NOUN
biomedich-274	48	2	1	1	NUM
biomedich-274	48	3	.	.	PUNCT
biomedich-274	48	4	mechanism	mechanism	NOUN
biomedich-274	48	5	of	of	ADP
biomedich-274	48	6	entry	entry	NOUN
biomedich-274	48	7	of	of	ADP
biomedich-274	48	8	sarscov-2	sarscov-2	NUM
biomedich-274	48	9	into	into	ADP
biomedich-274	48	10	the	the	DET
biomedich-274	48	11	cells	cell	NOUN
biomedich-274	48	12	through	through	ADP
biomedich-274	48	13	ace2	ace2	NOUN
biomedich-274	48	14	membrane	membrane	NOUN
biomedich-274	48	15	protein	protein	NOUN
biomedich-274	48	16	materials	material	NOUN
biomedich-274	48	17	and	and	CCONJ
biomedich-274	48	18	methods	method	NOUN
biomedich-274	48	19	macromolecule	macromolecule	NOUN
biomedich-274	48	20	preparation	preparation	NOUN
biomedich-274	48	21	the	the	DET
biomedich-274	48	22	3d	3d	NUM
biomedich-274	48	23	structure	structure	NOUN
biomedich-274	48	24	of	of	ADP
biomedich-274	48	25	the	the	DET
biomedich-274	48	26	ace2	ace2	NOUN
biomedich-274	48	27	protein	protein	NOUN
biomedich-274	48	28	was	be	AUX
biomedich-274	48	29	retrieved	retrieve	VERB
biomedich-274	48	30	from	from	ADP
biomedich-274	48	31	rcsb	rcsb	ADJ
biomedich-274	48	32	-	-	PUNCT
biomedich-274	48	33	protein	protein	NOUN
biomedich-274	48	34	data	datum	NOUN
biomedich-274	48	35	bank	bank	NOUN
biomedich-274	48	36	database	database	NOUN
biomedich-274	48	37	in	in	ADP
biomedich-274	48	38	pdb	pdb	PROPN
biomedich-274	48	39	format	format	NOUN
biomedich-274	48	40	(	(	PUNCT
biomedich-274	48	41	pdb	pdb	PROPN
biomedich-274	48	42	i	i	PROPN
biomedich-274	48	43	d	d	PROPN
biomedich-274	48	44	:	:	PUNCT
biomedich-274	48	45	1r42	1r42	NUM
biomedich-274	48	46	)	)	PUNCT
biomedich-274	48	47	(	(	PUNCT
biomedich-274	48	48	towler	towler	NOUN
biomedich-274	48	49	et	et	PROPN
biomedich-274	48	50	al	al	PROPN
biomedich-274	48	51	.	.	PROPN
biomedich-274	48	52	2004a	2004a	NUM
biomedich-274	48	53	)	)	PUNCT
biomedich-274	48	54	.	.	PUNCT
biomedich-274	49	1	x	x	X
biomedich-274	49	2	-	-	PUNCT
biomedich-274	49	3	ray	ray	NOUN
biomedich-274	49	4	crystallography	crystallography	NOUN
biomedich-274	49	5	method	method	NOUN
biomedich-274	49	6	was	be	AUX
biomedich-274	49	7	used	use	VERB
biomedich-274	49	8	for	for	ADP
biomedich-274	49	9	the	the	DET
biomedich-274	49	10	determination	determination	NOUN
biomedich-274	49	11	of	of	ADP
biomedich-274	49	12	the	the	DET
biomedich-274	49	13	structure	structure	NOUN
biomedich-274	49	14	of	of	ADP
biomedich-274	49	15	the	the	DET
biomedich-274	49	16	macromolecule	macromolecule	NOUN
biomedich-274	49	17	.	.	PUNCT
biomedich-274	50	1	the	the	DET
biomedich-274	50	2	macromolecule	macromolecule	NOUN
biomedich-274	50	3	was	be	AUX
biomedich-274	50	4	prepared	prepare	VERB
biomedich-274	50	5	by	by	ADP
biomedich-274	50	6	removing	remove	VERB
biomedich-274	50	7	the	the	DET
biomedich-274	50	8	unwanted	unwanted	ADJ
biomedich-274	50	9	water	water	NOUN
biomedich-274	50	10	molecules	molecule	NOUN
biomedich-274	50	11	,	,	PUNCT
biomedich-274	50	12	heteroatoms	heteroatom	NOUN
biomedich-274	50	13	and	and	CCONJ
biomedich-274	50	14	ligands	ligand	NOUN
biomedich-274	50	15	from	from	ADP
biomedich-274	50	16	the	the	DET
biomedich-274	50	17	structure	structure	NOUN
biomedich-274	50	18	of	of	ADP
biomedich-274	50	19	protein	protein	NOUN
biomedich-274	50	20	on	on	ADP
biomedich-274	50	21	software	software	NOUN
biomedich-274	50	22	biovia	biovia	NOUN
biomedich-274	50	23	discovery	discovery	PROPN
biomedich-274	50	24	studio	studio	PROPN
biomedich-274	50	25	visualizer	visualizer	PROPN
biomedich-274	50	26	v17.2.0.16349	v17.2.0.16349	NOUN
biomedich-274	50	27	.	.	PUNCT
biomedich-274	51	1	the	the	DET
biomedich-274	51	2	cleaning	cleaning	NOUN
biomedich-274	51	3	of	of	ADP
biomedich-274	51	4	protein	protein	NOUN
biomedich-274	51	5	helps	help	VERB
biomedich-274	51	6	to	to	PART
biomedich-274	51	7	purely	purely	ADV
biomedich-274	51	8	observe	observe	VERB
biomedich-274	51	9	the	the	DET
biomedich-274	51	10	interaction	interaction	NOUN
biomedich-274	51	11	between	between	ADP
biomedich-274	51	12	ligand	ligand	NOUN
biomedich-274	51	13	and	and	CCONJ
biomedich-274	51	14	the	the	DET
biomedich-274	51	15	target	target	NOUN
biomedich-274	51	16	protein	protein	NOUN
biomedich-274	51	17	residues	residue	NOUN
biomedich-274	51	18	,	,	PUNCT
biomedich-274	51	19	without	without	ADP
biomedich-274	51	20	any	any	DET
biomedich-274	51	21	influence	influence	NOUN
biomedich-274	51	22	of	of	ADP
biomedich-274	51	23	these	these	DET
biomedich-274	51	24	unnecessary	unnecessary	ADJ
biomedich-274	51	25	entities	entity	NOUN
biomedich-274	51	26	.	.	PUNCT
biomedich-274	52	1	ligand	ligand	ADJ
biomedich-274	52	2	preparation	preparation	NOUN
biomedich-274	52	3	the	the	DET
biomedich-274	52	4	ligands	ligand	NOUN
biomedich-274	52	5	selected	select	VERB
biomedich-274	52	6	were	be	AUX
biomedich-274	52	7	the	the	DET
biomedich-274	52	8	flavone	flavone	NOUN
biomedich-274	52	9	glycosides	glycoside	NOUN
biomedich-274	52	10	and	and	CCONJ
biomedich-274	52	11	their	their	PRON
biomedich-274	52	12	structures	structure	NOUN
biomedich-274	52	13	were	be	AUX
biomedich-274	52	14	acquired	acquire	VERB
biomedich-274	52	15	from	from	ADP
biomedich-274	52	16	pubchem	pubchem	NOUN
biomedich-274	52	17	database	database	NOUN
biomedich-274	52	18	.	.	PUNCT
biomedich-274	53	1	ibrahim	ibrahim	PROPN
biomedich-274	53	2	&	&	CCONJ
biomedich-274	53	3	ul	ul	PROPN
biomedich-274	53	4	haq	haq	PROPN
biomedich-274	53	5	–	–	PUNCT
biomedich-274	53	6	flavone	flavone	NOUN
biomedich-274	53	7	glycosides	glycoside	NOUN
biomedich-274	53	8	attenuate	attenuate	VERB
biomedich-274	53	9	covid-19	covid-19	PROPN
biomedich-274	53	10	99	99	NUM
biomedich-274	53	11	perkinelmer	perkinelmer	NOUN
biomedich-274	53	12	chem	chem	NOUN
biomedich-274	53	13	3d	3d	NOUN
biomedich-274	53	14	16.0	16.0	NUM
biomedich-274	53	15	was	be	AUX
biomedich-274	53	16	used	use	VERB
biomedich-274	53	17	to	to	PART
biomedich-274	53	18	convert	convert	VERB
biomedich-274	53	19	the	the	DET
biomedich-274	53	20	3d	3d	NUM
biomedich-274	53	21	structure	structure	NOUN
biomedich-274	53	22	of	of	ADP
biomedich-274	53	23	the	the	DET
biomedich-274	53	24	ligands	ligand	NOUN
biomedich-274	53	25	into	into	ADP
biomedich-274	53	26	pdb	pdb	PROPN
biomedich-274	53	27	format	format	NOUN
biomedich-274	53	28	.	.	PUNCT
biomedich-274	54	1	luteolin	luteolin	PROPN
biomedich-274	54	2	3'glucoside	3'glucoside	NUM
biomedich-274	54	3	(	(	PUNCT
biomedich-274	54	4	l1	l1	PROPN
biomedich-274	54	5	)	)	PUNCT
biomedich-274	54	6	,	,	PUNCT
biomedich-274	54	7	isovitexin	isovitexin	NOUN
biomedich-274	54	8	(	(	PUNCT
biomedich-274	54	9	l2	l2	NOUN
biomedich-274	54	10	)	)	PUNCT
biomedich-274	54	11	,	,	PUNCT
biomedich-274	54	12	baicalin	baicalin	NOUN
biomedich-274	54	13	(	(	PUNCT
biomedich-274	54	14	l3	l3	PROPN
biomedich-274	54	15	)	)	PUNCT
biomedich-274	54	16	,	,	PUNCT
biomedich-274	54	17	scutellarin	scutellarin	NOUN
biomedich-274	54	18	(	(	PUNCT
biomedich-274	54	19	l4	l4	PROPN
biomedich-274	54	20	)	)	PUNCT
biomedich-274	54	21	,	,	PUNCT
biomedich-274	54	22	diosmin	diosmin	NOUN
biomedich-274	54	23	(	(	PUNCT
biomedich-274	54	24	l5	l5	PROPN
biomedich-274	54	25	)	)	PUNCT
biomedich-274	54	26	,	,	PUNCT
biomedich-274	54	27	apigenin	apigenin	VERB
biomedich-274	54	28	7	7	NUM
biomedich-274	54	29	-	-	PUNCT
biomedich-274	54	30	o	o	NOUN
biomedich-274	54	31	-	-	NOUN
biomedich-274	54	32	glucoside	glucoside	NOUN
biomedich-274	54	33	(	(	PUNCT
biomedich-274	54	34	l6	l6	PROPN
biomedich-274	54	35	)	)	PUNCT
biomedich-274	54	36	,	,	PUNCT
biomedich-274	54	37	isoorientin	isoorientin	ADJ
biomedich-274	54	38	(	(	PUNCT
biomedich-274	54	39	l7	l7	PROPN
biomedich-274	54	40	)	)	PUNCT
biomedich-274	54	41	,	,	PUNCT
biomedich-274	54	42	lonicerin	lonicerin	NOUN
biomedich-274	54	43	(	(	PUNCT
biomedich-274	54	44	l8	l8	PROPN
biomedich-274	54	45	)	)	PUNCT
biomedich-274	54	46	,	,	PUNCT
biomedich-274	54	47	tricin	tricin	VERB
biomedich-274	54	48	7	7	NUM
biomedich-274	54	49	-	-	PUNCT
biomedich-274	54	50	oglucouronide	oglucouronide	ADJ
biomedich-274	54	51	(	(	PUNCT
biomedich-274	54	52	l9	l9	PROPN
biomedich-274	54	53	)	)	PUNCT
biomedich-274	54	54	and	and	CCONJ
biomedich-274	54	55	swertisin	swertisin	PROPN
biomedich-274	54	56	(	(	PUNCT
biomedich-274	54	57	l10	l10	PROPN
biomedich-274	54	58	)	)	PUNCT
biomedich-274	54	59	were	be	AUX
biomedich-274	54	60	the	the	DET
biomedich-274	54	61	ligands	ligand	NOUN
biomedich-274	54	62	used	use	VERB
biomedich-274	54	63	for	for	ADP
biomedich-274	54	64	studying	study	VERB
biomedich-274	54	65	their	their	PRON
biomedich-274	54	66	potential	potential	NOUN
biomedich-274	54	67	for	for	ADP
biomedich-274	54	68	inhibition	inhibition	NOUN
biomedich-274	54	69	of	of	ADP
biomedich-274	54	70	ace2	ace2	NOUN
biomedich-274	54	71	protein	protein	NOUN
biomedich-274	54	72	receptor	receptor	NOUN
biomedich-274	54	73	for	for	ADP
biomedich-274	54	74	preventing	prevent	VERB
biomedich-274	54	75	the	the	DET
biomedich-274	54	76	entry	entry	NOUN
biomedich-274	54	77	of	of	ADP
biomedich-274	54	78	sars	sar	NOUN
biomedich-274	54	79	-	-	PUNCT
biomedich-274	54	80	cov2	cov2	PROPN
biomedich-274	54	81	into	into	ADP
biomedich-274	54	82	the	the	DET
biomedich-274	54	83	cells	cell	NOUN
biomedich-274	54	84	containing	contain	VERB
biomedich-274	54	85	ace2	ace2	PROPN
biomedich-274	54	86	membrane	membrane	NOUN
biomedich-274	54	87	protein	protein	NOUN
biomedich-274	54	88	,	,	PUNCT
biomedich-274	54	89	as	as	SCONJ
biomedich-274	54	90	shown	show	VERB
biomedich-274	54	91	in	in	ADP
biomedich-274	54	92	table	table	NOUN
biomedich-274	54	93	1	1	NUM
biomedich-274	54	94	.	.	PUNCT
biomedich-274	55	1	the	the	DET
biomedich-274	55	2	two	two	NUM
biomedich-274	55	3	-	-	PUNCT
biomedich-274	55	4	dimensional	dimensional	ADJ
biomedich-274	55	5	structures	structure	NOUN
biomedich-274	55	6	of	of	ADP
biomedich-274	55	7	the	the	DET
biomedich-274	55	8	ligands	ligand	NOUN
biomedich-274	55	9	l1	l1	PROPN
biomedich-274	55	10	to	to	ADP
biomedich-274	55	11	l10	l10	PROPN
biomedich-274	55	12	are	be	AUX
biomedich-274	55	13	shown	show	VERB
biomedich-274	55	14	in	in	ADP
biomedich-274	55	15	figure	figure	NOUN
biomedich-274	55	16	2	2	NUM
biomedich-274	55	17	.	.	PUNCT
biomedich-274	55	18	table	table	NOUN
biomedich-274	55	19	1	1	NUM
biomedich-274	55	20	.	.	PUNCT
biomedich-274	56	1	the	the	DET
biomedich-274	56	2	table	table	NOUN
biomedich-274	56	3	shows	show	VERB
biomedich-274	56	4	the	the	DET
biomedich-274	56	5	list	list	NOUN
biomedich-274	56	6	of	of	ADP
biomedich-274	56	7	flavone	flavone	NOUN
biomedich-274	56	8	glycoside	glycoside	NOUN
biomedich-274	56	9	ligands	ligand	NOUN
biomedich-274	56	10	(	(	PUNCT
biomedich-274	56	11	l1	l1	PROPN
biomedich-274	56	12	to	to	ADP
biomedich-274	56	13	l10	l10	PROPN
biomedich-274	56	14	)	)	PUNCT
biomedich-274	56	15	in	in	ADP
biomedich-274	56	16	this	this	DET
biomedich-274	56	17	study	study	NOUN
biomedich-274	56	18	,	,	PUNCT
biomedich-274	56	19	their	their	PRON
biomedich-274	56	20	chemical	chemical	NOUN
biomedich-274	56	21	structure	structure	NOUN
biomedich-274	56	22	,	,	PUNCT
biomedich-274	56	23	botanical	botanical	ADJ
biomedich-274	56	24	source	source	NOUN
biomedich-274	56	25	and	and	CCONJ
biomedich-274	56	26	iupac	iupac	NOUN
biomedich-274	56	27	names	name	NOUN
biomedich-274	56	28	.	.	PUNCT
biomedich-274	57	1	serial	serial	ADJ
biomedich-274	57	2	number	number	NOUN
biomedich-274	57	3	ligands	ligand	VERB
biomedich-274	57	4	pubchem	pubchem	NOUN
biomedich-274	57	5	i	i	PROPN
biomedich-274	57	6	d	d	PROPN
biomedich-274	57	7	structure	structure	PROPN
biomedich-274	57	8	botanical	botanical	PROPN
biomedich-274	57	9	source	source	PROPN
biomedich-274	57	10	literature	literature	PROPN
biomedich-274	57	11	source	source	NOUN
biomedich-274	57	12	l1	l1	PROPN
biomedich-274	57	13	luteolin	luteolin	PROPN
biomedich-274	58	1	3'glucoside	3'glucoside	NUM
biomedich-274	58	2	12309350	12309350	NUM
biomedich-274	58	3	podocarpus	podocarpus	PROPN
biomedich-274	58	4	nivalis	nivali	NOUN
biomedich-274	58	5	pubchem	pubchem	NOUN
biomedich-274	58	6	l2	l2	NOUN
biomedich-274	58	7	isovitexin	isovitexin	NOUN
biomedich-274	58	8	162350	162350	NUM
biomedich-274	58	9	carex	carex	PROPN
biomedich-274	58	10	fraseriana	fraseriana	PROPN
biomedich-274	58	11	pubchem	pubchem	PROPN
biomedich-274	58	12	l3	l3	PROPN
biomedich-274	58	13	baicalin	baicalin	PROPN
biomedich-274	58	14	64982	64982	NUM
biomedich-274	58	15	scutellaria	scutellaria	NOUN
biomedich-274	58	16	amoena	amoena	PROPN
biomedich-274	58	17	pubchem	pubchem	PROPN
biomedich-274	58	18	l4	l4	PROPN
biomedich-274	58	19	scutellarin	scutellarin	PROPN
biomedich-274	58	20	185617	185617	NUM
biomedich-274	58	21	scoparia	scoparia	PROPN
biomedich-274	58	22	dulcis	dulcis	PROPN
biomedich-274	58	23	pubchem	pubchem	PROPN
biomedich-274	58	24	l5	l5	PROPN
biomedich-274	58	25	diosmin	diosmin	PROPN
biomedich-274	58	26	5281613	5281613	NUM
biomedich-274	58	27	asyneuma	asyneuma	NOUN
biomedich-274	58	28	argutum	argutum	PROPN
biomedich-274	58	29	pubchem	pubchem	PROPN
biomedich-274	58	30	l6	l6	PROPN
biomedich-274	58	31	apigenin	apigenin	ADJ
biomedich-274	58	32	7o	7o	NUM
biomedich-274	58	33	-	-	PUNCT
biomedich-274	58	34	glucoside	glucoside	ADJ
biomedich-274	58	35	44257792	44257792	NUM
biomedich-274	58	36	lonicera	lonicera	NOUN
biomedich-274	58	37	japonica	japonica	PROPN
biomedich-274	58	38	pubchem	pubchem	NOUN
biomedich-274	58	39	100	100	NUM
biomedich-274	58	40	biology	biology	NOUN
biomedich-274	58	41	,	,	PUNCT
biomedich-274	58	42	medicine	medicine	NOUN
biomedich-274	58	43	,	,	PUNCT
biomedich-274	58	44	&	&	CCONJ
biomedich-274	58	45	natural	natural	ADJ
biomedich-274	58	46	product	product	NOUN
biomedich-274	58	47	chemistry	chemistry	NOUN
biomedich-274	58	48	12	12	NUM
biomedich-274	58	49	(	(	PUNCT
biomedich-274	58	50	1	1	NUM
biomedich-274	58	51	)	)	PUNCT
biomedich-274	58	52	,	,	PUNCT
biomedich-274	58	53	2023	2023	NUM
biomedich-274	58	54	:	:	PUNCT
biomedich-274	58	55	97	97	NUM
biomedich-274	58	56	-	-	SYM
biomedich-274	58	57	108	108	NUM
biomedich-274	58	58	serial	serial	ADJ
biomedich-274	58	59	number	number	NOUN
biomedich-274	58	60	ligands	ligand	VERB
biomedich-274	58	61	pubchem	pubchem	NOUN
biomedich-274	58	62	i	i	PROPN
biomedich-274	58	63	d	d	PROPN
biomedich-274	58	64	structure	structure	PROPN
biomedich-274	58	65	botanical	botanical	PROPN
biomedich-274	58	66	source	source	PROPN
biomedich-274	58	67	literature	literature	PROPN
biomedich-274	58	68	source	source	PROPN
biomedich-274	58	69	l7	l7	PROPN
biomedich-274	58	70	isoorientin	isoorientin	PROPN
biomedich-274	58	71	114776	114776	NUM
biomedich-274	58	72	carex	carex	PROPN
biomedich-274	58	73	fraseriana	fraseriana	PROPN
biomedich-274	58	74	pubchem	pubchem	PROPN
biomedich-274	58	75	l8	l8	PROPN
biomedich-274	58	76	lonicerin	lonicerin	PROPN
biomedich-274	58	77	5282152	5282152	NUM
biomedich-274	59	1	lonicera	lonicera	NOUN
biomedich-274	59	2	japonica	japonica	PROPN
biomedich-274	59	3	pubchem	pubchem	PROPN
biomedich-274	59	4	l9	l9	PROPN
biomedich-274	59	5	tricin	tricin	VERB
biomedich-274	59	6	7	7	NUM
biomedich-274	59	7	-	-	PUNCT
biomedich-274	59	8	oglucouronide	oglucouronide	ADJ
biomedich-274	59	9	101939793	101939793	NUM
biomedich-274	59	10	scutellaria	scutellaria	NOUN
biomedich-274	59	11	discolor	discolor	VERB
biomedich-274	59	12	pubchem	pubchem	NOUN
biomedich-274	59	13	l10	l10	PROPN
biomedich-274	59	14	swertisin	swertisin	VERB
biomedich-274	59	15	124034	124034	NUM
biomedich-274	59	16	gentiana	gentiana	PROPN
biomedich-274	59	17	orbicularis	orbicularis	PROPN
biomedich-274	59	18	pubchem	pubchem	PROPN
biomedich-274	59	19	ibrahim	ibrahim	PROPN
biomedich-274	59	20	&	&	CCONJ
biomedich-274	59	21	ul	ul	PROPN
biomedich-274	59	22	haq	haq	PROPN
biomedich-274	59	23	–	–	PUNCT
biomedich-274	59	24	flavone	flavone	NOUN
biomedich-274	59	25	glycosides	glycoside	NOUN
biomedich-274	59	26	attenuate	attenuate	VERB
biomedich-274	59	27	covid-19	covid-19	PROPN
biomedich-274	59	28	101	101	NUM
biomedich-274	59	29	figure	figure	NOUN
biomedich-274	59	30	2	2	NUM
biomedich-274	59	31	.	.	PUNCT
biomedich-274	60	1	the	the	DET
biomedich-274	60	2	figure	figure	NOUN
biomedich-274	60	3	shows	show	VERB
biomedich-274	60	4	the	the	DET
biomedich-274	60	5	chemical	chemical	NOUN
biomedich-274	60	6	structures	structure	NOUN
biomedich-274	60	7	of	of	ADP
biomedich-274	60	8	the	the	DET
biomedich-274	60	9	ligands	ligand	NOUN
biomedich-274	60	10	l1	l1	PROPN
biomedich-274	60	11	to	to	ADP
biomedich-274	60	12	l10	l10	PROPN
biomedich-274	60	13	,	,	PUNCT
biomedich-274	60	14	along	along	ADP
biomedich-274	60	15	with	with	ADP
biomedich-274	60	16	their	their	PRON
biomedich-274	60	17	iupac	iupac	NOUN
biomedich-274	60	18	names	name	NOUN
biomedich-274	60	19	obtained	obtain	VERB
biomedich-274	60	20	from	from	ADP
biomedich-274	60	21	pubchem	pubchem	NOUN
biomedich-274	60	22	.	.	PUNCT
biomedich-274	61	1	results	result	NOUN
biomedich-274	61	2	and	and	CCONJ
biomedich-274	61	3	discussion	discussion	NOUN
biomedich-274	61	4	molecular	molecular	ADJ
biomedich-274	61	5	docking	docking	NOUN
biomedich-274	61	6	analysis	analysis	NOUN
biomedich-274	61	7	&	&	CCONJ
biomedich-274	61	8	results	result	VERB
biomedich-274	61	9	a	a	DET
biomedich-274	61	10	molecular	molecular	ADJ
biomedich-274	61	11	docking	docking	NOUN
biomedich-274	61	12	technique	technique	NOUN
biomedich-274	61	13	has	have	AUX
biomedich-274	61	14	been	be	AUX
biomedich-274	61	15	very	very	ADV
biomedich-274	61	16	handy	handy	ADJ
biomedich-274	61	17	in	in	ADP
biomedich-274	61	18	drug	drug	NOUN
biomedich-274	61	19	discovery	discovery	NOUN
biomedich-274	61	20	by	by	ADP
biomedich-274	61	21	pinpointing	pinpoint	VERB
biomedich-274	61	22	the	the	DET
biomedich-274	61	23	drug	drug	NOUN
biomedich-274	61	24	leads	lead	VERB
biomedich-274	61	25	having	have	VERB
biomedich-274	61	26	auspicious	auspicious	ADJ
biomedich-274	61	27	therapeutic	therapeutic	ADJ
biomedich-274	61	28	activity	activity	NOUN
biomedich-274	61	29	(	(	PUNCT
biomedich-274	61	30	ferreira	ferreira	PROPN
biomedich-274	61	31	et	et	PROPN
biomedich-274	61	32	al	al	PROPN
biomedich-274	61	33	.	.	PROPN
biomedich-274	61	34	2015	2015	NUM
biomedich-274	61	35	)	)	PUNCT
biomedich-274	61	36	.	.	PUNCT
biomedich-274	62	1	the	the	DET
biomedich-274	62	2	molecular	molecular	ADJ
biomedich-274	62	3	docking	docking	NOUN
biomedich-274	62	4	was	be	AUX
biomedich-274	62	5	performed	perform	VERB
biomedich-274	62	6	using	use	VERB
biomedich-274	62	7	pyrx	pyrx	NOUN
biomedich-274	62	8	virtual	virtual	ADJ
biomedich-274	62	9	screening	screening	NOUN
biomedich-274	62	10	tool	tool	NOUN
biomedich-274	62	11	that	that	PRON
biomedich-274	62	12	is	be	AUX
biomedich-274	62	13	highly	highly	ADV
biomedich-274	62	14	reliable	reliable	ADJ
biomedich-274	62	15	as	as	SCONJ
biomedich-274	62	16	it	it	PRON
biomedich-274	62	17	works	work	VERB
biomedich-274	62	18	on	on	ADP
biomedich-274	62	19	the	the	DET
biomedich-274	62	20	configuration	configuration	NOUN
biomedich-274	62	21	of	of	ADP
biomedich-274	62	22	autodock	autodock	PROPN
biomedich-274	62	23	vina	vina	PROPN
biomedich-274	62	24	(	(	PUNCT
biomedich-274	62	25	ekins	ekin	NOUN
biomedich-274	62	26	,	,	PUNCT
biomedich-274	62	27	mestres	mestre	NOUN
biomedich-274	62	28	,	,	PUNCT
biomedich-274	62	29	and	and	CCONJ
biomedich-274	62	30	testa	testa	NOUN
biomedich-274	62	31	2007	2007	NUM
biomedich-274	62	32	)	)	PUNCT
biomedich-274	62	33	.	.	PUNCT
biomedich-274	63	1	for	for	ADP
biomedich-274	63	2	the	the	DET
biomedich-274	63	3	visualization	visualization	NOUN
biomedich-274	63	4	of	of	ADP
biomedich-274	63	5	protein	protein	NOUN
biomedich-274	63	6	-	-	PUNCT
biomedich-274	63	7	ligand	ligand	NOUN
biomedich-274	63	8	interactions	interaction	NOUN
biomedich-274	63	9	,	,	PUNCT
biomedich-274	63	10	biovia	biovia	PROPN
biomedich-274	63	11	discovery	discovery	PROPN
biomedich-274	63	12	studio	studio	PROPN
biomedich-274	63	13	visualizer	visualizer	NOUN
biomedich-274	63	14	software	software	NOUN
biomedich-274	63	15	v17.2.0.16349	v17.2.0.16349	ADV
biomedich-274	63	16	was	be	AUX
biomedich-274	63	17	utilized	utilize	VERB
biomedich-274	63	18	.	.	PUNCT
biomedich-274	64	1	it	it	PRON
biomedich-274	64	2	provided	provide	VERB
biomedich-274	64	3	distinct	distinct	ADJ
biomedich-274	64	4	display	display	NOUN
biomedich-274	64	5	of	of	ADP
biomedich-274	64	6	the	the	DET
biomedich-274	64	7	2d	2d	NOUN
biomedich-274	64	8	and	and	CCONJ
biomedich-274	64	9	3d	3d	NUM
biomedich-274	64	10	interactions	interaction	NOUN
biomedich-274	64	11	along	along	ADP
biomedich-274	64	12	with	with	ADP
biomedich-274	64	13	the	the	DET
biomedich-274	64	14	bond	bond	NOUN
biomedich-274	64	15	lengths	length	NOUN
biomedich-274	64	16	,	,	PUNCT
biomedich-274	64	17	aromatic	aromatic	NOUN
biomedich-274	64	18	,	,	PUNCT
biomedich-274	64	19	hydrophobic	hydrophobic	NOUN
biomedich-274	64	20	interactions	interaction	NOUN
biomedich-274	64	21	etc	etc	X
biomedich-274	64	22	.	.	X
biomedich-274	65	1	promising	promise	VERB
biomedich-274	65	2	results	result	NOUN
biomedich-274	65	3	were	be	AUX
biomedich-274	65	4	witnessed	witness	VERB
biomedich-274	65	5	after	after	ADP
biomedich-274	65	6	the	the	DET
biomedich-274	65	7	molecular	molecular	ADJ
biomedich-274	65	8	docking	docking	NOUN
biomedich-274	65	9	analysis	analysis	NOUN
biomedich-274	65	10	of	of	ADP
biomedich-274	65	11	human	human	ADJ
biomedich-274	65	12	ace2	ace2	NOUN
biomedich-274	65	13	protein	protein	NOUN
biomedich-274	65	14	receptor	receptor	NOUN
biomedich-274	65	15	with	with	ADP
biomedich-274	65	16	ligands	ligand	NOUN
biomedich-274	65	17	l1	l1	PROPN
biomedich-274	65	18	to	to	ADP
biomedich-274	65	19	l10	l10	PROPN
biomedich-274	65	20	,	,	PUNCT
biomedich-274	65	21	as	as	SCONJ
biomedich-274	65	22	shown	show	VERB
biomedich-274	65	23	in	in	ADP
biomedich-274	65	24	table	table	NOUN
biomedich-274	65	25	2	2	NUM
biomedich-274	65	26	.	.	NOUN
biomedich-274	65	27	102	102	NUM
biomedich-274	65	28	biology	biology	NOUN
biomedich-274	65	29	,	,	PUNCT
biomedich-274	65	30	medicine	medicine	NOUN
biomedich-274	65	31	,	,	PUNCT
biomedich-274	65	32	&	&	CCONJ
biomedich-274	65	33	natural	natural	ADJ
biomedich-274	65	34	product	product	NOUN
biomedich-274	65	35	chemistry	chemistry	NOUN
biomedich-274	65	36	12	12	NUM
biomedich-274	65	37	(	(	PUNCT
biomedich-274	65	38	1	1	NUM
biomedich-274	65	39	)	)	PUNCT
biomedich-274	65	40	,	,	PUNCT
biomedich-274	65	41	2023	2023	NUM
biomedich-274	65	42	:	:	PUNCT
biomedich-274	65	43	97	97	NUM
biomedich-274	65	44	-	-	SYM
biomedich-274	65	45	108	108	NUM
biomedich-274	65	46	table	table	NOUN
biomedich-274	65	47	2	2	NUM
biomedich-274	65	48	.	.	PUNCT
biomedich-274	66	1	the	the	DET
biomedich-274	66	2	table	table	NOUN
biomedich-274	66	3	shows	show	VERB
biomedich-274	66	4	the	the	DET
biomedich-274	66	5	findings	finding	NOUN
biomedich-274	66	6	of	of	ADP
biomedich-274	66	7	the	the	DET
biomedich-274	66	8	molecular	molecular	ADJ
biomedich-274	66	9	docking	docking	NOUN
biomedich-274	66	10	and	and	CCONJ
biomedich-274	66	11	scoring	scoring	NOUN
biomedich-274	66	12	analysis	analysis	NOUN
biomedich-274	66	13	performed	perform	VERB
biomedich-274	66	14	for	for	ADP
biomedich-274	66	15	ligands	ligand	NOUN
biomedich-274	66	16	,	,	PUNCT
biomedich-274	66	17	l1	l1	PROPN
biomedich-274	66	18	to	to	ADP
biomedich-274	66	19	l10	l10	PROPN
biomedich-274	66	20	.	.	PUNCT
biomedich-274	67	1	ligand	ligand	ADJ
biomedich-274	67	2	-	-	PUNCT
biomedich-274	67	3	protein	protein	NOUN
biomedich-274	67	4	interaction	interaction	NOUN
biomedich-274	67	5	binding	bind	VERB
biomedich-274	67	6	energy	energy	NOUN
biomedich-274	67	7	(	(	PUNCT
biomedich-274	67	8	kcal	kcal	NOUN
biomedich-274	67	9	/	/	SYM
biomedich-274	67	10	mol	mol	NOUN
biomedich-274	67	11	)	)	PUNCT
biomedich-274	67	12	bonding	bonding	NOUN
biomedich-274	67	13	residues	residue	NOUN
biomedich-274	67	14	type	type	NOUN
biomedich-274	67	15	of	of	ADP
biomedich-274	67	16	bond	bond	NOUN
biomedich-274	67	17	bond	bond	NOUN
biomedich-274	67	18	length	length	NOUN
biomedich-274	67	19	(	(	PUNCT
biomedich-274	67	20	å	å	NOUN
biomedich-274	67	21	)	)	PUNCT
biomedich-274	67	22	other	other	ADJ
biomedich-274	67	23	residues	residue	NOUN
biomedich-274	67	24	l1	l1	PROPN
biomedich-274	67	25	-7.5	-7.5	PRON
biomedich-274	67	26	his	his	PRON
biomedich-274	67	27	378	378	NUM
biomedich-274	67	28	pi	pi	NOUN
biomedich-274	67	29	-	-	PUNCT
biomedich-274	67	30	pi	pi	NOUN
biomedich-274	67	31	5.61	5.61	NUM
biomedich-274	67	32	ala	ala	NOUN
biomedich-274	67	33	348	348	NUM
biomedich-274	67	34	,	,	PUNCT
biomedich-274	67	35	asp	asp	PROPN
biomedich-274	67	36	350	350	NUM
biomedich-274	67	37	,	,	PUNCT
biomedich-274	67	38	tyr	tyr	PROPN
biomedich-274	67	39	385	385	NUM
biomedich-274	67	40	his	his	PRON
biomedich-274	67	41	401	401	NUM
biomedich-274	67	42	pi	pi	NOUN
biomedich-274	67	43	-	-	PUNCT
biomedich-274	67	44	pi	pi	NOUN
biomedich-274	67	45	4.43	4.43	NUM
biomedich-274	67	46	glu	glu	NOUN
biomedich-274	67	47	402	402	NUM
biomedich-274	67	48	pianion	pianion	NOUN
biomedich-274	67	49	3.49	3.49	NUM
biomedich-274	67	50	,	,	PUNCT
biomedich-274	67	51	3.75	3.75	NUM
biomedich-274	67	52	l2	l2	NOUN
biomedich-274	67	53	-7.1	-7.1	PUNCT
biomedich-274	67	54	his	his	PRON
biomedich-274	67	55	378	378	NUM
biomedich-274	67	56	pi	pi	NOUN
biomedich-274	67	57	-	-	PUNCT
biomedich-274	67	58	pi	pi	NOUN
biomedich-274	67	59	4.93	4.93	NUM
biomedich-274	67	60	asp	asp	NOUN
biomedich-274	67	61	382	382	NUM
biomedich-274	67	62	,	,	PUNCT
biomedich-274	67	63	asn	asn	VERB
biomedich-274	67	64	394	394	NUM
biomedich-274	67	65	his	his	PRON
biomedich-274	67	66	401	401	NUM
biomedich-274	67	67	pi	pi	NOUN
biomedich-274	67	68	-	-	PUNCT
biomedich-274	67	69	pi	pi	NOUN
biomedich-274	67	70	5.71	5.71	NUM
biomedich-274	67	71	glu	glu	NOUN
biomedich-274	67	72	402	402	NUM
biomedich-274	67	73	pianion	pianion	NOUN
biomedich-274	67	74	4.20	4.20	NUM
biomedich-274	67	75	l3	l3	NOUN
biomedich-274	67	76	-8.1	-8.1	PUNCT
biomedich-274	68	1	his	his	PRON
biomedich-274	68	2	401	401	NUM
biomedich-274	68	3	h	h	NOUN
biomedich-274	68	4	bond	bond	NOUN
biomedich-274	68	5	2.53	2.53	NUM
biomedich-274	68	6	ser	ser	NOUN
biomedich-274	68	7	44	44	NUM
biomedich-274	68	8	,	,	PUNCT
biomedich-274	68	9	asp	asp	PROPN
biomedich-274	68	10	350	350	NUM
biomedich-274	68	11	,	,	PUNCT
biomedich-274	68	12	asp	asp	PROPN
biomedich-274	68	13	382	382	NUM
biomedich-274	68	14	l4	l4	PROPN
biomedich-274	68	15	-8.2	-8.2	PROPN
biomedich-274	68	16	his	his	PRON
biomedich-274	68	17	401	401	NUM
biomedich-274	68	18	h	h	NOUN
biomedich-274	68	19	bond	bond	NOUN
biomedich-274	68	20	2.50	2.50	NUM
biomedich-274	68	21	ser	ser	NOUN
biomedich-274	68	22	44	44	NUM
biomedich-274	68	23	,	,	PUNCT
biomedich-274	68	24	trp	trp	PROPN
biomedich-274	68	25	349	349	NUM
biomedich-274	68	26	,	,	PUNCT
biomedich-274	68	27	asp	asp	NOUN
biomedich-274	68	28	350	350	NUM
biomedich-274	68	29	,	,	PUNCT
biomedich-274	68	30	asp	asp	NOUN
biomedich-274	68	31	382	382	NUM
biomedich-274	68	32	,	,	PUNCT
biomedich-274	68	33	tyr	tyr	PROPN
biomedich-274	68	34	385	385	NUM
biomedich-274	68	35	l5	l5	PROPN
biomedich-274	68	36	-9.3	-9.3	NOUN
biomedich-274	68	37	his	his	PRON
biomedich-274	68	38	378	378	NUM
biomedich-274	68	39	h	h	NOUN
biomedich-274	68	40	bond	bond	NOUN
biomedich-274	68	41	3.31	3.31	NUM
biomedich-274	68	42	phe	phe	NOUN
biomedich-274	68	43	40	40	NUM
biomedich-274	68	44	,	,	PUNCT
biomedich-274	68	45	asp	asp	PROPN
biomedich-274	68	46	350	350	NUM
biomedich-274	68	47	,	,	PUNCT
biomedich-274	68	48	asp	asp	NOUN
biomedich-274	68	49	382	382	NUM
biomedich-274	68	50	,	,	PUNCT
biomedich-274	68	51	asn	asn	VERB
biomedich-274	68	52	394	394	NUM
biomedich-274	68	53	his	his	PRON
biomedich-274	68	54	401	401	NUM
biomedich-274	68	55	pialkyl	pialkyl	NOUN
biomedich-274	68	56	5.12	5.12	NUM
biomedich-274	68	57	l6	l6	PROPN
biomedich-274	68	58	-7.9	-7.9	ADP
biomedich-274	68	59	his	his	PRON
biomedich-274	68	60	401	401	NUM
biomedich-274	68	61	pidonor	pidonor	NOUN
biomedich-274	68	62	h	h	PROPN
biomedich-274	68	63	bond	bond	NOUN
biomedich-274	68	64	2.58	2.58	NUM
biomedich-274	68	65	ser	ser	NOUN
biomedich-274	68	66	44	44	NUM
biomedich-274	68	67	,	,	PUNCT
biomedich-274	68	68	ala	ala	PROPN
biomedich-274	68	69	348	348	NUM
biomedich-274	68	70	,	,	PUNCT
biomedich-274	68	71	trp	trp	PROPN
biomedich-274	68	72	349	349	NUM
biomedich-274	68	73	,	,	PUNCT
biomedich-274	68	74	asp	asp	PROPN
biomedich-274	68	75	350	350	NUM
biomedich-274	68	76	glu	glu	NOUN
biomedich-274	68	77	402	402	NUM
biomedich-274	68	78	h	h	NOUN
biomedich-274	68	79	bond	bond	PROPN
biomedich-274	68	80	2.38	2.38	PROPN
biomedich-274	68	81	l7	l7	PROPN
biomedich-274	68	82	-7.4	-7.4	X
biomedich-274	68	83	his	his	PRON
biomedich-274	68	84	378	378	NUM
biomedich-274	68	85	pi	pi	NOUN
biomedich-274	68	86	-	-	PUNCT
biomedich-274	68	87	pi	pi	NOUN
biomedich-274	68	88	4.93	4.93	NUM
biomedich-274	68	89	ala	ala	NOUN
biomedich-274	68	90	348	348	NUM
biomedich-274	68	91	,	,	PUNCT
biomedich-274	68	92	glu	glu	NOUN
biomedich-274	68	93	375	375	NUM
biomedich-274	68	94	his	his	PRON
biomedich-274	68	95	401	401	NUM
biomedich-274	68	96	pi	pi	NOUN
biomedich-274	68	97	-	-	PUNCT
biomedich-274	68	98	pi	pi	NOUN
biomedich-274	68	99	5.72	5.72	NUM
biomedich-274	68	100	l8	l8	PROPN
biomedich-274	68	101	-8.4	-8.4	VERB
biomedich-274	68	102	his	his	PRON
biomedich-274	68	103	378	378	NUM
biomedich-274	68	104	pi	pi	NOUN
biomedich-274	68	105	-	-	PUNCT
biomedich-274	68	106	pi	pi	NOUN
biomedich-274	68	107	4.94	4.94	NUM
biomedich-274	68	108	ser	ser	NOUN
biomedich-274	68	109	44	44	NUM
biomedich-274	68	110	,	,	PUNCT
biomedich-274	68	111	ala	ala	PROPN
biomedich-274	68	112	348	348	NUM
biomedich-274	68	113	,	,	PUNCT
biomedich-274	68	114	trp	trp	PROPN
biomedich-274	68	115	349	349	NUM
biomedich-274	68	116	,	,	PUNCT
biomedich-274	68	117	tyr	tyr	PROPN
biomedich-274	68	118	385	385	NUM
biomedich-274	68	119	,	,	PUNCT
biomedich-274	68	120	tyr	tyr	PROPN
biomedich-274	68	121	515	515	NUM
biomedich-274	68	122	glu	glu	NOUN
biomedich-274	68	123	402	402	NUM
biomedich-274	68	124	pi	pi	NOUN
biomedich-274	68	125	-	-	PUNCT
biomedich-274	68	126	anion	anion	NOUN
biomedich-274	68	127	3.57	3.57	NUM
biomedich-274	68	128	l9	l9	PROPN
biomedich-274	68	129	-8.0	-8.0	PUNCT
biomedich-274	68	130	glu	glu	PROPN
biomedich-274	68	131	402	402	NUM
biomedich-274	68	132	h	h	NOUN
biomedich-274	68	133	bond	bond	NOUN
biomedich-274	68	134	2.11	2.11	NUM
biomedich-274	68	135	trp	trp	PROPN
biomedich-274	68	136	349	349	NUM
biomedich-274	68	137	,	,	PUNCT
biomedich-274	68	138	asp	asp	NOUN
biomedich-274	68	139	350	350	NUM
biomedich-274	68	140	,	,	PUNCT
biomedich-274	68	141	arg	arg	VERB
biomedich-274	68	142	514	514	NUM
biomedich-274	68	143	l10	l10	PROPN
biomedich-274	68	144	-7.3	-7.3	VERB
biomedich-274	69	1	his	his	PRON
biomedich-274	69	2	378	378	NUM
biomedich-274	69	3	h	h	NOUN
biomedich-274	69	4	bond	bond	NOUN
biomedich-274	69	5	,	,	PUNCT
biomedich-274	69	6	pi	pi	NOUN
biomedich-274	69	7	-	-	PUNCT
biomedich-274	69	8	pi	pi	NOUN
biomedich-274	69	9	3.11	3.11	NUM
biomedich-274	69	10	,	,	PUNCT
biomedich-274	69	11	4.95	4.95	NUM
biomedich-274	69	12	pro	pro	X
biomedich-274	69	13	346	346	NUM
biomedich-274	69	14	,	,	PUNCT
biomedich-274	69	15	asp	asp	NOUN
biomedich-274	69	16	382	382	NUM
biomedich-274	69	17	,	,	PUNCT
biomedich-274	69	18	arg	arg	VERB
biomedich-274	69	19	393	393	NUM
biomedich-274	69	20	his	his	PRON
biomedich-274	69	21	401	401	NUM
biomedich-274	69	22	h	h	NOUN
biomedich-274	69	23	bond	bond	NOUN
biomedich-274	69	24	,	,	PUNCT
biomedich-274	69	25	pi	pi	NOUN
biomedich-274	69	26	-	-	PUNCT
biomedich-274	69	27	pi	pi	NOUN
biomedich-274	69	28	2.53	2.53	NUM
biomedich-274	69	29	,	,	PUNCT
biomedich-274	69	30	5.77	5.77	NUM
biomedich-274	69	31	all	all	DET
biomedich-274	69	32	the	the	DET
biomedich-274	69	33	ligands	ligand	NOUN
biomedich-274	69	34	l1	l1	PROPN
biomedich-274	69	35	to	to	ADP
biomedich-274	69	36	l10	l10	PROPN
biomedich-274	69	37	,	,	PUNCT
biomedich-274	69	38	exhibited	exhibit	VERB
biomedich-274	69	39	their	their	PRON
biomedich-274	69	40	firm	firm	ADJ
biomedich-274	69	41	interactions	interaction	NOUN
biomedich-274	69	42	with	with	ADP
biomedich-274	69	43	the	the	DET
biomedich-274	69	44	binding	bind	VERB
biomedich-274	69	45	site	site	NOUN
biomedich-274	69	46	residues	residue	NOUN
biomedich-274	69	47	of	of	ADP
biomedich-274	69	48	human	human	ADJ
biomedich-274	69	49	ace2	ace2	NOUN
biomedich-274	69	50	protein	protein	NOUN
biomedich-274	69	51	receptor	receptor	NOUN
biomedich-274	69	52	i.e.	i.e.	X
biomedich-274	69	53	his	his	PRON
biomedich-274	69	54	378	378	NUM
biomedich-274	69	55	,	,	PUNCT
biomedich-274	69	56	his	his	PRON
biomedich-274	69	57	401	401	NUM
biomedich-274	69	58	and	and	CCONJ
biomedich-274	69	59	his	his	PRON
biomedich-274	69	60	402	402	NUM
biomedich-274	69	61	(	(	PUNCT
biomedich-274	69	62	towler	towler	NOUN
biomedich-274	69	63	et	et	PROPN
biomedich-274	69	64	al	al	PROPN
biomedich-274	69	65	.	.	PROPN
biomedich-274	69	66	2004b	2004b	NUM
biomedich-274	69	67	)	)	PUNCT
biomedich-274	69	68	,	,	PUNCT
biomedich-274	69	69	with	with	ADP
biomedich-274	69	70	a	a	DET
biomedich-274	69	71	binding	bind	VERB
biomedich-274	69	72	affinity	affinity	NOUN
biomedich-274	69	73	ranging	range	VERB
biomedich-274	69	74	from	from	ADP
biomedich-274	69	75	-9.3	-9.3	PROPN
biomedich-274	69	76	to	to	ADP
biomedich-274	69	77	-7.1	-7.1	PUNCT
biomedich-274	69	78	kcal	kcal	PROPN
biomedich-274	69	79	/	/	SYM
biomedich-274	69	80	mol	mol	PROPN
biomedich-274	69	81	.	.	PUNCT
biomedich-274	70	1	the	the	DET
biomedich-274	70	2	best	well	ADV
biomedich-274	70	3	binding	bind	VERB
biomedich-274	70	4	energy	energy	NOUN
biomedich-274	70	5	of	of	ADP
biomedich-274	70	6	9.3	9.3	NUM
biomedich-274	70	7	kcal	kcal	NOUN
biomedich-274	70	8	/	/	SYM
biomedich-274	70	9	mol	mol	PROPN
biomedich-274	70	10	was	be	AUX
biomedich-274	70	11	expressed	express	VERB
biomedich-274	70	12	by	by	ADP
biomedich-274	70	13	diosmin	diosmin	PROPN
biomedich-274	70	14	(	(	PUNCT
biomedich-274	70	15	l5	l5	PROPN
biomedich-274	70	16	)	)	PUNCT
biomedich-274	70	17	,	,	PUNCT
biomedich-274	70	18	while	while	SCONJ
biomedich-274	70	19	the	the	DET
biomedich-274	70	20	binding	bind	VERB
biomedich-274	70	21	energies	energy	NOUN
biomedich-274	70	22	exhibited	exhibit	VERB
biomedich-274	70	23	by	by	ADP
biomedich-274	70	24	other	other	ADJ
biomedich-274	70	25	compounds	compound	NOUN
biomedich-274	70	26	in	in	ADP
biomedich-274	70	27	this	this	DET
biomedich-274	70	28	study	study	NOUN
biomedich-274	70	29	were	be	AUX
biomedich-274	70	30	-8.4	-8.4	INTJ
biomedich-274	70	31	kcal	kcal	NOUN
biomedich-274	70	32	/	/	SYM
biomedich-274	70	33	mol	mol	NOUN
biomedich-274	70	34	for	for	ADP
biomedich-274	70	35	lonicerin	lonicerin	NOUN
biomedich-274	70	36	(	(	PUNCT
biomedich-274	70	37	l8	l8	PROPN
biomedich-274	70	38	)	)	PUNCT
biomedich-274	70	39	,	,	PUNCT
biomedich-274	70	40	-8.2	-8.2	PROPN
biomedich-274	70	41	kcal	kcal	PROPN
biomedich-274	70	42	/	/	SYM
biomedich-274	70	43	mol	mol	PROPN
biomedich-274	70	44	for	for	ADP
biomedich-274	70	45	scutellarin	scutellarin	NOUN
biomedich-274	70	46	(	(	PUNCT
biomedich-274	70	47	l4	l4	PROPN
biomedich-274	70	48	)	)	PUNCT
biomedich-274	70	49	,	,	PUNCT
biomedich-274	70	50	-8.1	-8.1	PROPN
biomedich-274	70	51	kcal	kcal	PROPN
biomedich-274	70	52	/	/	SYM
biomedich-274	70	53	mol	mol	NOUN
biomedich-274	70	54	for	for	ADP
biomedich-274	70	55	baicalin	baicalin	NOUN
biomedich-274	70	56	(	(	PUNCT
biomedich-274	70	57	l3	l3	PROPN
biomedich-274	70	58	)	)	PUNCT
biomedich-274	70	59	,	,	PUNCT
biomedich-274	70	60	-8.0	-8.0	PUNCT
biomedich-274	70	61	kcal	kcal	NOUN
biomedich-274	70	62	/	/	SYM
biomedich-274	70	63	mol	mol	NOUN
biomedich-274	70	64	for	for	ADP
biomedich-274	70	65	tricin	tricin	VERB
biomedich-274	70	66	7	7	NUM
biomedich-274	70	67	-	-	PUNCT
biomedich-274	70	68	o	o	NOUN
biomedich-274	70	69	-	-	NOUN
biomedich-274	70	70	glucouronide	glucouronide	ADJ
biomedich-274	70	71	(	(	PUNCT
biomedich-274	70	72	l9	l9	PROPN
biomedich-274	70	73	)	)	PUNCT
biomedich-274	70	74	,	,	PUNCT
biomedich-274	70	75	7.9	7.9	NUM
biomedich-274	70	76	kcal	kcal	NOUN
biomedich-274	70	77	/	/	SYM
biomedich-274	70	78	mol	mol	PROPN
biomedich-274	70	79	for	for	ADP
biomedich-274	70	80	apigenin	apigenin	ADJ
biomedich-274	70	81	7	7	NUM
biomedich-274	70	82	-	-	PUNCT
biomedich-274	70	83	o	o	NOUN
biomedich-274	70	84	-	-	NOUN
biomedich-274	70	85	glucoside	glucoside	NOUN
biomedich-274	70	86	(	(	PUNCT
biomedich-274	70	87	l6	l6	PROPN
biomedich-274	70	88	)	)	PUNCT
biomedich-274	70	89	,	,	PUNCT
biomedich-274	70	90	-7.5	-7.5	NOUN
biomedich-274	70	91	kcal	kcal	NOUN
biomedich-274	70	92	/	/	SYM
biomedich-274	70	93	mol	mol	PROPN
biomedich-274	70	94	for	for	ADP
biomedich-274	70	95	luteolin	luteolin	PROPN
biomedich-274	70	96	3'-glucoside	3'-glucoside	PROPN
biomedich-274	70	97	(	(	PUNCT
biomedich-274	70	98	l1	l1	PROPN
biomedich-274	70	99	)	)	PUNCT
biomedich-274	70	100	,	,	PUNCT
biomedich-274	70	101	-7.4	-7.4	PUNCT
biomedich-274	70	102	kcal	kcal	PROPN
biomedich-274	70	103	/	/	SYM
biomedich-274	70	104	mol	mol	NOUN
biomedich-274	70	105	for	for	ADP
biomedich-274	70	106	isoorientin	isoorientin	ADJ
biomedich-274	70	107	(	(	PUNCT
biomedich-274	70	108	l7	l7	PROPN
biomedich-274	70	109	)	)	PUNCT
biomedich-274	70	110	,	,	PUNCT
biomedich-274	70	111	-7.3	-7.3	ADV
biomedich-274	70	112	kcal	kcal	NOUN
biomedich-274	70	113	/	/	SYM
biomedich-274	70	114	mol	mol	PROPN
biomedich-274	70	115	for	for	ADP
biomedich-274	70	116	swertisin	swertisin	NOUN
biomedich-274	70	117	(	(	PUNCT
biomedich-274	70	118	l10	l10	PROPN
biomedich-274	70	119	)	)	PUNCT
biomedich-274	70	120	and	and	CCONJ
biomedich-274	70	121	-7.1	-7.1	PUNCT
biomedich-274	70	122	kcal	kcal	NOUN
biomedich-274	70	123	/	/	SYM
biomedich-274	70	124	mol	mol	NOUN
biomedich-274	70	125	for	for	ADP
biomedich-274	70	126	isovitexin	isovitexin	NOUN
biomedich-274	70	127	(	(	PUNCT
biomedich-274	70	128	l2	l2	NOUN
biomedich-274	70	129	)	)	PUNCT
biomedich-274	70	130	.	.	PUNCT
biomedich-274	71	1	all	all	DET
biomedich-274	71	2	the	the	DET
biomedich-274	71	3	ligands	ligand	NOUN
biomedich-274	71	4	showed	show	VERB
biomedich-274	71	5	absolute	absolute	ADJ
biomedich-274	71	6	interactions	interaction	NOUN
biomedich-274	71	7	with	with	ADP
biomedich-274	71	8	the	the	DET
biomedich-274	71	9	active	active	ADJ
biomedich-274	71	10	site	site	NOUN
biomedich-274	71	11	residues	residue	NOUN
biomedich-274	71	12	of	of	ADP
biomedich-274	71	13	human	human	ADJ
biomedich-274	71	14	ace2	ace2	NOUN
biomedich-274	71	15	enzyme	enzyme	NOUN
biomedich-274	71	16	.	.	PUNCT
biomedich-274	72	1	luteolin	luteolin	PROPN
biomedich-274	72	2	3'-glucoside	3'-glucoside	ADV
biomedich-274	72	3	(	(	PUNCT
biomedich-274	72	4	l1	l1	PROPN
biomedich-274	72	5	)	)	PUNCT
biomedich-274	72	6	and	and	CCONJ
biomedich-274	72	7	isovitexin	isovitexin	NOUN
biomedich-274	72	8	(	(	PUNCT
biomedich-274	72	9	l2	l2	NOUN
biomedich-274	72	10	)	)	PUNCT
biomedich-274	72	11	were	be	AUX
biomedich-274	72	12	bound	bind	VERB
biomedich-274	72	13	to	to	ADP
biomedich-274	72	14	his	his	PRON
biomedich-274	72	15	378	378	NUM
biomedich-274	72	16	,	,	PUNCT
biomedich-274	72	17	his	his	PRON
biomedich-274	72	18	401	401	NUM
biomedich-274	72	19	and	and	CCONJ
biomedich-274	72	20	glu	glu	NOUN
biomedich-274	72	21	402	402	NUM
biomedich-274	72	22	with	with	ADP
biomedich-274	72	23	considerable	considerable	ADJ
biomedich-274	72	24	binding	bind	VERB
biomedich-274	72	25	energies	energy	NOUN
biomedich-274	72	26	.	.	PUNCT
biomedich-274	73	1	ligands	ligand	NOUN
biomedich-274	73	2	,	,	PUNCT
biomedich-274	73	3	baicalin	baicalin	NOUN
biomedich-274	73	4	(	(	PUNCT
biomedich-274	73	5	l3	l3	PROPN
biomedich-274	73	6	)	)	PUNCT
biomedich-274	73	7	and	and	CCONJ
biomedich-274	73	8	scutellarin	scutellarin	NOUN
biomedich-274	73	9	(	(	PUNCT
biomedich-274	73	10	l4	l4	PROPN
biomedich-274	73	11	)	)	PUNCT
biomedich-274	73	12	manifested	manifest	VERB
biomedich-274	73	13	binding	bind	VERB
biomedich-274	73	14	with	with	ADP
biomedich-274	73	15	his	his	PRON
biomedich-274	73	16	401	401	NUM
biomedich-274	73	17	residues	residue	NOUN
biomedich-274	73	18	with	with	ADP
biomedich-274	73	19	shorter	short	ADJ
biomedich-274	73	20	bond	bond	NOUN
biomedich-274	73	21	lengths	length	NOUN
biomedich-274	73	22	.	.	PUNCT
biomedich-274	74	1	diosmin	diosmin	NOUN
biomedich-274	74	2	(	(	PUNCT
biomedich-274	74	3	l5	l5	PROPN
biomedich-274	74	4	)	)	PUNCT
biomedich-274	74	5	and	and	CCONJ
biomedich-274	74	6	apigenin	apigenin	VERB
biomedich-274	74	7	7	7	NUM
biomedich-274	74	8	-	-	PUNCT
biomedich-274	74	9	o	o	NOUN
biomedich-274	74	10	-	-	NOUN
biomedich-274	74	11	glucoside	glucoside	NOUN
biomedich-274	74	12	(	(	PUNCT
biomedich-274	74	13	l6	l6	PROPN
biomedich-274	74	14	)	)	PUNCT
biomedich-274	74	15	showed	show	VERB
biomedich-274	74	16	their	their	PRON
biomedich-274	74	17	interactions	interaction	NOUN
biomedich-274	74	18	with	with	ADP
biomedich-274	74	19	his	his	PRON
biomedich-274	74	20	378	378	NUM
biomedich-274	74	21	,	,	PUNCT
biomedich-274	74	22	his	his	PRON
biomedich-274	74	23	401	401	NUM
biomedich-274	74	24	and	and	CCONJ
biomedich-274	74	25	his	his	PRON
biomedich-274	74	26	401	401	NUM
biomedich-274	74	27	,	,	PUNCT
biomedich-274	74	28	glu	glu	NOUN
biomedich-274	74	29	402	402	NUM
biomedich-274	74	30	residues	residue	NOUN
biomedich-274	74	31	,	,	PUNCT
biomedich-274	74	32	respectively	respectively	ADV
biomedich-274	74	33	with	with	ADP
biomedich-274	74	34	reasonable	reasonable	ADJ
biomedich-274	74	35	bond	bond	NOUN
biomedich-274	74	36	lengths	length	NOUN
biomedich-274	74	37	.	.	PUNCT
biomedich-274	75	1	ligands	ligand	NOUN
biomedich-274	75	2	,	,	PUNCT
biomedich-274	75	3	isoorientin	isoorientin	ADJ
biomedich-274	75	4	(	(	PUNCT
biomedich-274	75	5	l7	l7	PROPN
biomedich-274	75	6	)	)	PUNCT
biomedich-274	75	7	,	,	PUNCT
biomedich-274	75	8	lonicerin	lonicerin	NOUN
biomedich-274	75	9	(	(	PUNCT
biomedich-274	75	10	l8	l8	PROPN
biomedich-274	75	11	)	)	PUNCT
biomedich-274	75	12	,	,	PUNCT
biomedich-274	75	13	tricin	tricin	VERB
biomedich-274	75	14	7	7	NUM
biomedich-274	75	15	-	-	PUNCT
biomedich-274	75	16	o	o	NOUN
biomedich-274	75	17	-	-	NOUN
biomedich-274	75	18	glucouronide	glucouronide	ADJ
biomedich-274	75	19	(	(	PUNCT
biomedich-274	75	20	l9	l9	PROPN
biomedich-274	75	21	)	)	PUNCT
biomedich-274	75	22	and	and	CCONJ
biomedich-274	75	23	swertisin	swertisin	PROPN
biomedich-274	75	24	(	(	PUNCT
biomedich-274	75	25	l10	l10	PROPN
biomedich-274	75	26	)	)	PUNCT
biomedich-274	75	27	,	,	PUNCT
biomedich-274	75	28	all	all	PRON
biomedich-274	75	29	demonstrated	demonstrate	VERB
biomedich-274	75	30	their	their	PRON
biomedich-274	75	31	robust	robust	ADJ
biomedich-274	75	32	binding	bind	VERB
biomedich-274	75	33	affinities	affinity	NOUN
biomedich-274	75	34	with	with	ADP
biomedich-274	75	35	active	active	ADJ
biomedich-274	75	36	residues	residue	NOUN
biomedich-274	75	37	his	his	PRON
biomedich-274	75	38	378	378	NUM
biomedich-274	75	39	,	,	PUNCT
biomedich-274	75	40	his	his	PRON
biomedich-274	75	41	401	401	NUM
biomedich-274	75	42	and	and	CCONJ
biomedich-274	75	43	glu	glu	NOUN
biomedich-274	75	44	402	402	NUM
biomedich-274	75	45	with	with	ADP
biomedich-274	75	46	substantial	substantial	ADJ
biomedich-274	75	47	bond	bond	NOUN
biomedich-274	75	48	lengths	length	NOUN
biomedich-274	75	49	,	,	PUNCT
biomedich-274	75	50	with	with	ADP
biomedich-274	75	51	pi	pi	NOUN
biomedich-274	75	52	-	-	PUNCT
biomedich-274	75	53	pi	pi	NOUN
biomedich-274	75	54	and	and	CCONJ
biomedich-274	75	55	hydrogen	hydrogen	NOUN
biomedich-274	75	56	bonds	bond	NOUN
biomedich-274	75	57	.	.	PUNCT
biomedich-274	76	1	strong	strong	ADJ
biomedich-274	76	2	interactions	interaction	NOUN
biomedich-274	76	3	and	and	CCONJ
biomedich-274	76	4	short	short	ADJ
biomedich-274	76	5	bond	bond	NOUN
biomedich-274	76	6	lengths	length	NOUN
biomedich-274	76	7	also	also	ADV
biomedich-274	76	8	appeared	appear	VERB
biomedich-274	76	9	with	with	ADP
biomedich-274	76	10	some	some	DET
biomedich-274	76	11	other	other	ADJ
biomedich-274	76	12	residues	residue	NOUN
biomedich-274	76	13	i.e.	i.e.	X
biomedich-274	76	14	ser	ser	NOUN
biomedich-274	76	15	44	44	NUM
biomedich-274	76	16	,	,	PUNCT
biomedich-274	76	17	ala	ala	PROPN
biomedich-274	76	18	248	248	NUM
biomedich-274	76	19	,	,	PUNCT
biomedich-274	76	20	trp	trp	PROPN
biomedich-274	76	21	349	349	NUM
biomedich-274	76	22	and	and	CCONJ
biomedich-274	76	23	asp	asp	PROPN
biomedich-274	76	24	350	350	NUM
biomedich-274	76	25	may	may	AUX
biomedich-274	76	26	also	also	ADV
biomedich-274	76	27	be	be	AUX
biomedich-274	76	28	the	the	DET
biomedich-274	76	29	active	active	ADJ
biomedich-274	76	30	residues	residue	NOUN
biomedich-274	76	31	of	of	ADP
biomedich-274	76	32	ace2	ace2	NOUN
biomedich-274	76	33	protein	protein	NOUN
biomedich-274	76	34	.	.	PUNCT
biomedich-274	77	1	the	the	DET
biomedich-274	77	2	interactions	interaction	NOUN
biomedich-274	77	3	of	of	ADP
biomedich-274	77	4	the	the	DET
biomedich-274	77	5	best	well	ADV
biomedich-274	77	6	docked	docked	ADJ
biomedich-274	77	7	ligand	ligand	ADJ
biomedich-274	77	8	diosmin	diosmin	NOUN
biomedich-274	77	9	(	(	PUNCT
biomedich-274	77	10	l5	l5	PROPN
biomedich-274	77	11	)	)	PUNCT
biomedich-274	77	12	are	be	AUX
biomedich-274	77	13	shown	show	VERB
biomedich-274	77	14	in	in	ADP
biomedich-274	77	15	figure	figure	NOUN
biomedich-274	77	16	3	3	NUM
biomedich-274	77	17	.	.	PUNCT
biomedich-274	78	1	while	while	SCONJ
biomedich-274	78	2	figure	figure	NOUN
biomedich-274	78	3	4	4	NUM
biomedich-274	78	4	demonstrates	demonstrate	VERB
biomedich-274	78	5	the	the	DET
biomedich-274	78	6	interactions	interaction	NOUN
biomedich-274	78	7	of	of	ADP
biomedich-274	78	8	top	top	ADJ
biomedich-274	78	9	three	three	NUM
biomedich-274	78	10	ligands	ligand	NOUN
biomedich-274	78	11	with	with	ADP
biomedich-274	78	12	highest	high	ADJ
biomedich-274	78	13	binding	bind	VERB
biomedich-274	78	14	energies	energy	NOUN
biomedich-274	78	15	(	(	PUNCT
biomedich-274	78	16	l5	l5	PROPN
biomedich-274	78	17	,	,	PUNCT
biomedich-274	78	18	l8	l8	PROPN
biomedich-274	78	19	and	and	CCONJ
biomedich-274	78	20	l4	l4	PROPN
biomedich-274	78	21	)	)	PUNCT
biomedich-274	78	22	with	with	ADP
biomedich-274	78	23	ace2	ace2	NOUN
biomedich-274	78	24	binding	bind	VERB
biomedich-274	78	25	site	site	NOUN
biomedich-274	78	26	.	.	PUNCT
biomedich-274	79	1	ibrahim	ibrahim	PROPN
biomedich-274	79	2	&	&	CCONJ
biomedich-274	79	3	ul	ul	PROPN
biomedich-274	79	4	haq	haq	PROPN
biomedich-274	79	5	–	–	PUNCT
biomedich-274	79	6	flavone	flavone	NOUN
biomedich-274	79	7	glycosides	glycoside	NOUN
biomedich-274	79	8	attenuate	attenuate	VERB
biomedich-274	79	9	covid-19	covid-19	PROPN
biomedich-274	79	10	103	103	NUM
biomedich-274	79	11	figure	figure	NOUN
biomedich-274	79	12	3	3	NUM
biomedich-274	79	13	.	.	PUNCT
biomedich-274	80	1	the	the	DET
biomedich-274	80	2	best	well	ADV
biomedich-274	80	3	docked	docked	ADJ
biomedich-274	80	4	ligand	ligand	NOUN
biomedich-274	80	5	,	,	PUNCT
biomedich-274	80	6	diosmin	diosmin	NOUN
biomedich-274	80	7	(	(	PUNCT
biomedich-274	80	8	l5	l5	PROPN
biomedich-274	80	9	)	)	PUNCT
biomedich-274	80	10	blocking	block	VERB
biomedich-274	80	11	the	the	DET
biomedich-274	80	12	binding	bind	VERB
biomedich-274	80	13	site	site	NOUN
biomedich-274	80	14	of	of	ADP
biomedich-274	80	15	ace2	ace2	PROPN
biomedich-274	80	16	(	(	PUNCT
biomedich-274	80	17	a	a	NOUN
biomedich-274	80	18	)	)	PUNCT
biomedich-274	80	19	and	and	CCONJ
biomedich-274	80	20	2d	2d	NUM
biomedich-274	80	21	diagram	diagram	NOUN
biomedich-274	80	22	of	of	ADP
biomedich-274	80	23	interactions	interaction	NOUN
biomedich-274	80	24	of	of	ADP
biomedich-274	80	25	l5	l5	PROPN
biomedich-274	80	26	with	with	ADP
biomedich-274	80	27	active	active	ADJ
biomedich-274	80	28	site	site	NOUN
biomedich-274	80	29	residues	residue	NOUN
biomedich-274	80	30	(	(	PUNCT
biomedich-274	80	31	b	b	NOUN
biomedich-274	80	32	)	)	PUNCT
biomedich-274	80	33	.	.	PUNCT
biomedich-274	81	1	figure	figure	VERB
biomedich-274	81	2	4	4	NUM
biomedich-274	81	3	.	.	X
biomedich-274	81	4	3d	3d	NUM
biomedich-274	81	5	and	and	CCONJ
biomedich-274	81	6	2d	2d	NUM
biomedich-274	81	7	interactions	interaction	NOUN
biomedich-274	81	8	of	of	ADP
biomedich-274	81	9	top	top	ADJ
biomedich-274	81	10	three	three	NUM
biomedich-274	81	11	ligands	ligand	NOUN
biomedich-274	81	12	with	with	ADP
biomedich-274	81	13	respect	respect	NOUN
biomedich-274	81	14	to	to	ADP
biomedich-274	81	15	binding	bind	VERB
biomedich-274	81	16	energies	energy	NOUN
biomedich-274	81	17	(	(	PUNCT
biomedich-274	81	18	l5	l5	PROPN
biomedich-274	81	19	,	,	PUNCT
biomedich-274	81	20	l8	l8	PROPN
biomedich-274	81	21	and	and	CCONJ
biomedich-274	81	22	l4	l4	PROPN
biomedich-274	81	23	)	)	PUNCT
biomedich-274	81	24	respectively	respectively	ADV
biomedich-274	81	25	,	,	PUNCT
biomedich-274	81	26	with	with	ADP
biomedich-274	81	27	the	the	DET
biomedich-274	81	28	active	active	ADJ
biomedich-274	81	29	site	site	NOUN
biomedich-274	81	30	residues	residue	NOUN
biomedich-274	81	31	of	of	ADP
biomedich-274	81	32	ace2	ace2	NOUN
biomedich-274	81	33	protein	protein	NOUN
biomedich-274	81	34	.	.	PUNCT
biomedich-274	82	1	104	104	NUM
biomedich-274	82	2	biology	biology	NOUN
biomedich-274	82	3	,	,	PUNCT
biomedich-274	82	4	medicine	medicine	NOUN
biomedich-274	82	5	,	,	PUNCT
biomedich-274	82	6	&	&	CCONJ
biomedich-274	82	7	natural	natural	ADJ
biomedich-274	82	8	product	product	NOUN
biomedich-274	82	9	chemistry	chemistry	NOUN
biomedich-274	82	10	12	12	NUM
biomedich-274	82	11	(	(	PUNCT
biomedich-274	82	12	1	1	NUM
biomedich-274	82	13	)	)	PUNCT
biomedich-274	82	14	,	,	PUNCT
biomedich-274	82	15	2023	2023	NUM
biomedich-274	82	16	:	:	PUNCT
biomedich-274	82	17	97	97	NUM
biomedich-274	82	18	-	-	SYM
biomedich-274	82	19	108	108	NUM
biomedich-274	82	20	admet	admet	NOUN
biomedich-274	82	21	analysis	analysis	NOUN
biomedich-274	82	22	admet	admet	NOUN
biomedich-274	82	23	profile	profile	NOUN
biomedich-274	82	24	of	of	ADP
biomedich-274	82	25	a	a	DET
biomedich-274	82	26	specific	specific	ADJ
biomedich-274	82	27	ligand	ligand	NOUN
biomedich-274	82	28	serves	serve	VERB
biomedich-274	82	29	as	as	ADP
biomedich-274	82	30	a	a	DET
biomedich-274	82	31	surrogate	surrogate	NOUN
biomedich-274	82	32	for	for	SCONJ
biomedich-274	82	33	its	its	PRON
biomedich-274	82	34	fate	fate	NOUN
biomedich-274	82	35	to	to	PART
biomedich-274	82	36	be	be	AUX
biomedich-274	82	37	considered	consider	VERB
biomedich-274	82	38	as	as	ADP
biomedich-274	82	39	a	a	DET
biomedich-274	82	40	potential	potential	ADJ
biomedich-274	82	41	drug	drug	NOUN
biomedich-274	82	42	candidate	candidate	NOUN
biomedich-274	82	43	.	.	PUNCT
biomedich-274	83	1	swiss	swiss	ADJ
biomedich-274	83	2	adme	adme	NOUN
biomedich-274	83	3	was	be	AUX
biomedich-274	83	4	employed	employ	VERB
biomedich-274	83	5	for	for	ADP
biomedich-274	83	6	analyzing	analyze	VERB
biomedich-274	83	7	the	the	DET
biomedich-274	83	8	adme	adme	NOUN
biomedich-274	83	9	profile	profile	NOUN
biomedich-274	83	10	of	of	ADP
biomedich-274	83	11	the	the	DET
biomedich-274	83	12	potential	potential	ADJ
biomedich-274	83	13	drug	drug	NOUN
biomedich-274	83	14	candidates	candidate	NOUN
biomedich-274	83	15	in	in	ADP
biomedich-274	83	16	this	this	DET
biomedich-274	83	17	study	study	NOUN
biomedich-274	83	18	(	(	PUNCT
biomedich-274	83	19	daina	daina	PROPN
biomedich-274	83	20	,	,	PUNCT
biomedich-274	83	21	michielin	michielin	PROPN
biomedich-274	83	22	,	,	PUNCT
biomedich-274	83	23	and	and	CCONJ
biomedich-274	83	24	zoete	zoete	NOUN
biomedich-274	83	25	2017	2017	NUM
biomedich-274	83	26	)	)	PUNCT
biomedich-274	83	27	.	.	PUNCT
biomedich-274	84	1	toxicity	toxicity	NOUN
biomedich-274	84	2	profile	profile	NOUN
biomedich-274	84	3	was	be	AUX
biomedich-274	84	4	established	establish	VERB
biomedich-274	84	5	through	through	ADP
biomedich-274	84	6	datawarrior	datawarrior	ADJ
biomedich-274	84	7	v5.5.0	v5.5.0	NOUN
biomedich-274	84	8	(	(	PUNCT
biomedich-274	84	9	sander	sander	PROPN
biomedich-274	84	10	et	et	PROPN
biomedich-274	84	11	al	al	PROPN
biomedich-274	84	12	.	.	PROPN
biomedich-274	84	13	2015	2015	NUM
biomedich-274	84	14	)	)	PUNCT
biomedich-274	84	15	.	.	PUNCT
biomedich-274	85	1	the	the	DET
biomedich-274	85	2	orisis	orisis	NOUN
biomedich-274	85	3	property	property	NOUN
biomedich-274	85	4	explorer	explorer	NOUN
biomedich-274	85	5	was	be	AUX
biomedich-274	85	6	used	use	VERB
biomedich-274	85	7	for	for	ADP
biomedich-274	85	8	the	the	DET
biomedich-274	85	9	prediction	prediction	NOUN
biomedich-274	85	10	of	of	ADP
biomedich-274	85	11	druglikeness	druglikeness	NOUN
biomedich-274	85	12	score	score	NOUN
biomedich-274	85	13	of	of	ADP
biomedich-274	85	14	all	all	DET
biomedich-274	85	15	potential	potential	ADJ
biomedich-274	85	16	drug	drug	NOUN
biomedich-274	85	17	candidates	candidate	NOUN
biomedich-274	85	18	.	.	PUNCT
biomedich-274	86	1	the	the	DET
biomedich-274	86	2	molecular	molecular	ADJ
biomedich-274	86	3	weights	weight	NOUN
biomedich-274	86	4	of	of	ADP
biomedich-274	86	5	ligands	ligand	NOUN
biomedich-274	86	6	from	from	ADP
biomedich-274	86	7	l1	l1	PROPN
biomedich-274	86	8	to	to	ADP
biomedich-274	86	9	l10	l10	PROPN
biomedich-274	86	10	are	be	AUX
biomedich-274	86	11	448.38	448.38	NUM
biomedich-274	86	12	,	,	PUNCT
biomedich-274	86	13	432.38	432.38	NUM
biomedich-274	86	14	,	,	PUNCT
biomedich-274	86	15	446.36	446.36	NUM
biomedich-274	86	16	,	,	PUNCT
biomedich-274	86	17	462.36	462.36	NUM
biomedich-274	86	18	,	,	PUNCT
biomedich-274	86	19	608.54	608.54	NUM
biomedich-274	86	20	,	,	PUNCT
biomedich-274	86	21	432.38	432.38	NUM
biomedich-274	86	22	,	,	PUNCT
biomedich-274	86	23	448.38	448.38	NUM
biomedich-274	86	24	,	,	PUNCT
biomedich-274	86	25	594.52	594.52	NUM
biomedich-274	86	26	,	,	PUNCT
biomedich-274	86	27	506.41	506.41	NUM
biomedich-274	86	28	and	and	CCONJ
biomedich-274	86	29	446.40	446.40	NUM
biomedich-274	86	30	grams	gram	NOUN
biomedich-274	86	31	per	per	ADP
biomedich-274	86	32	mole	mole	NOUN
biomedich-274	86	33	(	(	PUNCT
biomedich-274	86	34	g	g	NOUN
biomedich-274	86	35	/	/	SYM
biomedich-274	86	36	mol	mol	NOUN
biomedich-274	86	37	)	)	PUNCT
biomedich-274	86	38	,	,	PUNCT
biomedich-274	86	39	respectively	respectively	ADV
biomedich-274	86	40	.	.	PUNCT
biomedich-274	87	1	the	the	DET
biomedich-274	87	2	highest	high	ADJ
biomedich-274	87	3	score	score	NOUN
biomedich-274	87	4	for	for	ADP
biomedich-274	87	5	bioavailability	bioavailability	NOUN
biomedich-274	87	6	was	be	AUX
biomedich-274	87	7	expressed	express	VERB
biomedich-274	87	8	by	by	ADP
biomedich-274	87	9	l2	l2	NOUN
biomedich-274	87	10	and	and	CCONJ
biomedich-274	87	11	l10	l10	NOUN
biomedich-274	87	12	i.e.	i.e.	X
biomedich-274	87	13	0.55	0.55	NUM
biomedich-274	87	14	.	.	PUNCT
biomedich-274	88	1	while	while	SCONJ
biomedich-274	88	2	l1	l1	PROPN
biomedich-274	88	3	,	,	PUNCT
biomedich-274	88	4	l5	l5	PROPN
biomedich-274	88	5	,	,	PUNCT
biomedich-274	88	6	l7	l7	PROPN
biomedich-274	88	7	,	,	PUNCT
biomedich-274	88	8	l8	l8	PROPN
biomedich-274	88	9	conveyed	convey	VERB
biomedich-274	88	10	their	their	PRON
biomedich-274	88	11	bioavailability	bioavailability	NOUN
biomedich-274	88	12	score	score	NOUN
biomedich-274	88	13	as	as	SCONJ
biomedich-274	88	14	0.17	0.17	NUM
biomedich-274	88	15	and	and	CCONJ
biomedich-274	88	16	a	a	DET
biomedich-274	88	17	bioavailability	bioavailability	NOUN
biomedich-274	88	18	score	score	NOUN
biomedich-274	88	19	of	of	ADP
biomedich-274	88	20	0.11	0.11	NUM
biomedich-274	88	21	was	be	AUX
biomedich-274	88	22	predicted	predict	VERB
biomedich-274	88	23	for	for	ADP
biomedich-274	88	24	l3	l3	NOUN
biomedich-274	88	25	,	,	PUNCT
biomedich-274	88	26	l4	l4	PROPN
biomedich-274	88	27	and	and	CCONJ
biomedich-274	88	28	l9	l9	PROPN
biomedich-274	88	29	.	.	PUNCT
biomedich-274	89	1	a	a	DET
biomedich-274	89	2	further	far	ADV
biomedich-274	89	3	invitro	invitro	NOUN
biomedich-274	89	4	and	and	CCONJ
biomedich-274	89	5	in	in	ADP
biomedich-274	89	6	-	-	PUNCT
biomedich-274	89	7	vivo	vivo	NOUN
biomedich-274	89	8	studies	study	NOUN
biomedich-274	89	9	are	be	AUX
biomedich-274	89	10	recommended	recommend	VERB
biomedich-274	89	11	for	for	ADP
biomedich-274	89	12	improvement	improvement	NOUN
biomedich-274	89	13	and	and	CCONJ
biomedich-274	89	14	tailoring	tailoring	NOUN
biomedich-274	89	15	of	of	ADP
biomedich-274	89	16	the	the	DET
biomedich-274	89	17	pharmacokinetic	pharmacokinetic	ADJ
biomedich-274	89	18	profile	profile	NOUN
biomedich-274	89	19	of	of	ADP
biomedich-274	89	20	these	these	DET
biomedich-274	89	21	potential	potential	ADJ
biomedich-274	89	22	drug	drug	NOUN
biomedich-274	89	23	candidates	candidate	NOUN
biomedich-274	89	24	,	,	PUNCT
biomedich-274	89	25	so	so	SCONJ
biomedich-274	89	26	that	that	SCONJ
biomedich-274	89	27	these	these	PRON
biomedich-274	89	28	could	could	AUX
biomedich-274	89	29	be	be	AUX
biomedich-274	89	30	formulated	formulate	VERB
biomedich-274	89	31	in	in	ADP
biomedich-274	89	32	such	such	DET
biomedich-274	89	33	a	a	DET
biomedich-274	89	34	way	way	NOUN
biomedich-274	89	35	that	that	PRON
biomedich-274	89	36	they	they	PRON
biomedich-274	89	37	may	may	AUX
biomedich-274	89	38	act	act	VERB
biomedich-274	89	39	as	as	ADP
biomedich-274	89	40	potent	potent	ADJ
biomedich-274	89	41	inhibitors	inhibitor	NOUN
biomedich-274	89	42	of	of	ADP
biomedich-274	89	43	ace2	ace2	NOUN
biomedich-274	89	44	in	in	ADP
biomedich-274	89	45	attenuating	attenuate	VERB
biomedich-274	89	46	sars	sar	NOUN
biomedich-274	89	47	-	-	PUNCT
biomedich-274	89	48	cov-2	cov-2	NOUN
biomedich-274	89	49	.	.	PUNCT
biomedich-274	90	1	the	the	DET
biomedich-274	90	2	toxicity	toxicity	NOUN
biomedich-274	90	3	profile	profile	NOUN
biomedich-274	90	4	of	of	ADP
biomedich-274	90	5	these	these	DET
biomedich-274	90	6	ligands	ligand	NOUN
biomedich-274	90	7	,	,	PUNCT
biomedich-274	90	8	studied	study	VERB
biomedich-274	90	9	on	on	ADP
biomedich-274	90	10	datawarrior	datawarrior	ADJ
biomedich-274	90	11	v5.5.0	v5.5.0	NOUN
biomedich-274	90	12	,	,	PUNCT
biomedich-274	90	13	was	be	AUX
biomedich-274	90	14	unremarkable	unremarkable	ADJ
biomedich-274	90	15	for	for	ADP
biomedich-274	90	16	all	all	DET
biomedich-274	90	17	the	the	DET
biomedich-274	90	18	ligands	ligand	NOUN
biomedich-274	90	19	,	,	PUNCT
biomedich-274	90	20	l1	l1	PROPN
biomedich-274	90	21	to	to	ADP
biomedich-274	90	22	l10	l10	PROPN
biomedich-274	90	23	.	.	PUNCT
biomedich-274	91	1	the	the	DET
biomedich-274	91	2	admet	admet	PROPN
biomedich-274	91	3	profile	profile	NOUN
biomedich-274	91	4	of	of	ADP
biomedich-274	91	5	ligands	ligand	NOUN
biomedich-274	91	6	l1	l1	PROPN
biomedich-274	91	7	to	to	ADP
biomedich-274	91	8	l10	l10	PROPN
biomedich-274	91	9	is	be	AUX
biomedich-274	91	10	shown	show	VERB
biomedich-274	91	11	in	in	ADP
biomedich-274	91	12	table	table	NOUN
biomedich-274	91	13	3	3	NUM
biomedich-274	91	14	.	.	PUNCT
biomedich-274	92	1	the	the	DET
biomedich-274	92	2	bioavailability	bioavailability	NOUN
biomedich-274	92	3	radar	radar	NOUN
biomedich-274	92	4	of	of	ADP
biomedich-274	92	5	diosmin	diosmin	PROPN
biomedich-274	92	6	(	(	PUNCT
biomedich-274	92	7	l5	l5	PROPN
biomedich-274	92	8	)	)	PUNCT
biomedich-274	92	9	is	be	AUX
biomedich-274	92	10	provided	provide	VERB
biomedich-274	92	11	in	in	ADP
biomedich-274	92	12	the	the	DET
biomedich-274	92	13	figure	figure	NOUN
biomedich-274	92	14	5	5	NUM
biomedich-274	92	15	.	.	PUNCT
biomedich-274	92	16	figure	figure	NOUN
biomedich-274	92	17	5	5	NUM
biomedich-274	92	18	.	.	PUNCT
biomedich-274	93	1	bioavailability	bioavailability	NOUN
biomedich-274	93	2	radar	radar	NOUN
biomedich-274	93	3	of	of	ADP
biomedich-274	93	4	the	the	DET
biomedich-274	93	5	best	well	ADV
biomedich-274	93	6	docked	docked	ADJ
biomedich-274	93	7	ligand	ligand	NOUN
biomedich-274	93	8	,	,	PUNCT
biomedich-274	93	9	diosmin	diosmin	NOUN
biomedich-274	93	10	(	(	PUNCT
biomedich-274	93	11	l5	l5	PROPN
biomedich-274	93	12	)	)	PUNCT
biomedich-274	93	13	,	,	PUNCT
biomedich-274	93	14	obtained	obtain	VERB
biomedich-274	93	15	through	through	ADP
biomedich-274	93	16	swissadme	swissadme	NOUN
biomedich-274	93	17	.	.	PUNCT
biomedich-274	94	1	table	table	NOUN
biomedich-274	94	2	3	3	NUM
biomedich-274	94	3	.	.	PUNCT
biomedich-274	95	1	the	the	DET
biomedich-274	95	2	table	table	NOUN
biomedich-274	95	3	represents	represent	VERB
biomedich-274	95	4	the	the	DET
biomedich-274	95	5	in	in	ADP
biomedich-274	95	6	-	-	PUNCT
biomedich-274	95	7	silico	silico	NOUN
biomedich-274	95	8	profiling	profiling	NOUN
biomedich-274	95	9	of	of	ADP
biomedich-274	95	10	admet	admet	ADJ
biomedich-274	95	11	,	,	PUNCT
biomedich-274	95	12	physicochemical	physicochemical	ADJ
biomedich-274	95	13	properties	property	NOUN
biomedich-274	95	14	,	,	PUNCT
biomedich-274	95	15	druglikeness	druglikeness	NOUN
biomedich-274	95	16	and	and	CCONJ
biomedich-274	95	17	toxicity	toxicity	NOUN
biomedich-274	95	18	of	of	ADP
biomedich-274	95	19	the	the	DET
biomedich-274	95	20	ligands	ligand	NOUN
biomedich-274	95	21	(	(	PUNCT
biomedich-274	95	22	l1	l1	PROPN
biomedich-274	95	23	to	to	ADP
biomedich-274	95	24	l10	l10	PROPN
biomedich-274	95	25	)	)	PUNCT
biomedich-274	95	26	drug	drug	NOUN
biomedich-274	95	27	candidates	candidate	NOUN
biomedich-274	95	28	l1	l1	PROPN
biomedich-274	95	29	l2	l2	PROPN
biomedich-274	95	30	l3	l3	PROPN
biomedich-274	95	31	l4	l4	PROPN
biomedich-274	95	32	l5	l5	PROPN
biomedich-274	95	33	l6	l6	PROPN
biomedich-274	95	34	l7	l7	PROPN
biomedich-274	95	35	l8	l8	PROPN
biomedich-274	95	36	l9	l9	PROPN
biomedich-274	95	37	l10	l10	PROPN
biomedich-274	95	38	physicochemical	physicochemical	ADJ
biomedich-274	95	39	properties	property	NOUN
biomedich-274	96	1	mol.w	mol.w	PROPN
biomedich-274	96	2	(	(	PUNCT
biomedich-274	96	3	g	g	NOUN
biomedich-274	96	4	/	/	SYM
biomedich-274	96	5	mol	mol	NOUN
biomedich-274	96	6	)	)	PUNCT
biomedich-274	96	7	448.38	448.38	NUM
biomedich-274	96	8	432.38	432.38	NUM
biomedich-274	96	9	446.36	446.36	NUM
biomedich-274	96	10	462.36	462.36	NUM
biomedich-274	96	11	608.54	608.54	NUM
biomedich-274	96	12	432.38	432.38	NUM
biomedich-274	96	13	448.38	448.38	NUM
biomedich-274	96	14	594.52	594.52	NUM
biomedich-274	96	15	506.41	506.41	NUM
biomedich-274	96	16	446.40	446.40	NUM
biomedich-274	96	17	h	h	NOUN
biomedich-274	96	18	-	-	PUNCT
biomedich-274	96	19	acc	acc	PROPN
biomedich-274	96	20	11	11	NUM
biomedich-274	96	21	10	10	NUM
biomedich-274	96	22	11	11	NUM
biomedich-274	96	23	12	12	NUM
biomedich-274	96	24	15	15	NUM
biomedich-274	96	25	10	10	NUM
biomedich-274	96	26	11	11	NUM
biomedich-274	96	27	15	15	NUM
biomedich-274	96	28	13	13	NUM
biomedich-274	96	29	10	10	NUM
biomedich-274	96	30	h	h	NOUN
biomedich-274	96	31	-	-	PUNCT
biomedich-274	96	32	don	don	ADJ
biomedich-274	96	33	7	7	NUM
biomedich-274	96	34	7	7	NUM
biomedich-274	96	35	6	6	NUM
biomedich-274	96	36	7	7	NUM
biomedich-274	96	37	8	8	NUM
biomedich-274	96	38	6	6	NUM
biomedich-274	96	39	8	8	NUM
biomedich-274	96	40	9	9	NUM
biomedich-274	96	41	6	6	NUM
biomedich-274	96	42	6	6	NUM
biomedich-274	96	43	n.r.b	n.r.b	NOUN
biomedich-274	96	44	4	4	NUM
biomedich-274	96	45	3	3	NUM
biomedich-274	96	46	4	4	NUM
biomedich-274	96	47	4	4	NUM
biomedich-274	96	48	7	7	NUM
biomedich-274	96	49	4	4	NUM
biomedich-274	96	50	3	3	NUM
biomedich-274	96	51	6	6	NUM
biomedich-274	96	52	6	6	NUM
biomedich-274	96	53	4	4	NUM
biomedich-274	96	54	tpsa	tpsa	NOUN
biomedich-274	96	55	(	(	PUNCT
biomedich-274	96	56	å²	å²	PROPN
biomedich-274	96	57	)	)	PUNCT
biomedich-274	96	58	190.28	190.28	NUM
biomedich-274	96	59	181.05	181.05	NUM
biomedich-274	96	60	187.12	187.12	NUM
biomedich-274	96	61	207.35	207.35	NUM
biomedich-274	96	62	238.20	238.20	NUM
biomedich-274	96	63	170.05	170.05	NUM
biomedich-274	96	64	201.28	201.28	NUM
biomedich-274	96	65	249.20	249.20	NUM
biomedich-274	96	66	205.58	205.58	NUM
biomedich-274	96	67	170.05	170.05	NUM
biomedich-274	96	68	log	log	NOUN
biomedich-274	96	69	p	p	PROPN
biomedich-274	96	70	-0.06	-0.06	NUM
biomedich-274	96	71	0.05	0.05	NUM
biomedich-274	96	72	0.22	0.22	NUM
biomedich-274	96	73	-0.20	-0.20	NUM
biomedich-274	96	74	-0.44	-0.44	NUM
biomedich-274	96	75	0.55	0.55	NUM
biomedich-274	96	76	-0.24	-0.24	NUM
biomedich-274	96	77	-1.03	-1.03	NUM
biomedich-274	96	78	0.30	0.30	NUM
biomedich-274	96	79	0.35	0.35	NUM
biomedich-274	96	80	b.sc	b.sc	NOUN
biomedich-274	96	81	0.17	0.17	NUM
biomedich-274	96	82	0.55	0.55	NUM
biomedich-274	96	83	0.11	0.11	NUM
biomedich-274	96	84	0.11	0.11	NUM
biomedich-274	96	85	0.17	0.17	NUM
biomedich-274	96	86	0.55	0.55	NUM
biomedich-274	96	87	0.17	0.17	NUM
biomedich-274	96	88	0.17	0.17	NUM
biomedich-274	96	89	0.11	0.11	NUM
biomedich-274	96	90	0.55	0.55	NUM
biomedich-274	96	91	drug	drug	NOUN
biomedich-274	96	92	-	-	PUNCT
biomedich-274	96	93	likeliness	likeliness	NOUN
biomedich-274	96	94	d.l.s	d.l.s	NOUN
biomedich-274	96	95	-3.4	-3.4	NOUN
biomedich-274	96	96	-1.2	-1.2	NOUN
biomedich-274	96	97	0.8	0.8	NUM
biomedich-274	96	98	1.04	1.04	NUM
biomedich-274	96	99	3.85	3.85	NUM
biomedich-274	96	100	-2.3	-2.3	NOUN
biomedich-274	96	101	-0.7	-0.7	PROPN
biomedich-274	96	102	2.4	2.4	NUM
biomedich-274	96	103	2.0	2.0	NUM
biomedich-274	96	104	-1.1	-1.1	NOUN
biomedich-274	96	105	n.l.v	n.l.v	NOUN
biomedich-274	96	106	2	2	NUM
biomedich-274	96	107	1	1	NUM
biomedich-274	96	108	2	2	NUM
biomedich-274	96	109	2	2	NUM
biomedich-274	96	110	3	3	NUM
biomedich-274	96	111	1	1	NUM
biomedich-274	96	112	2	2	NUM
biomedich-274	96	113	3	3	NUM
biomedich-274	96	114	3	3	NUM
biomedich-274	96	115	1	1	NUM
biomedich-274	96	116	metabolism	metabolism	NOUN
biomedich-274	96	117	cyp	cyp	NOUN
biomedich-274	96	118	1a2	1a2	INTJ
biomedich-274	97	1	no	no	INTJ
biomedich-274	97	2	no	no	INTJ
biomedich-274	98	1	no	no	INTJ
biomedich-274	98	2	no	no	INTJ
biomedich-274	99	1	no	no	INTJ
biomedich-274	99	2	no	no	INTJ
biomedich-274	100	1	no	no	INTJ
biomedich-274	100	2	no	no	INTJ
biomedich-274	101	1	no	no	INTJ
biomedich-274	101	2	no	no	INTJ
biomedich-274	101	3	cyp	cyp	ADJ
biomedich-274	101	4	2c19	2c19	NOUN
biomedich-274	102	1	no	no	INTJ
biomedich-274	102	2	no	no	INTJ
biomedich-274	103	1	no	no	INTJ
biomedich-274	103	2	no	no	INTJ
biomedich-274	104	1	no	no	INTJ
biomedich-274	104	2	no	no	INTJ
biomedich-274	105	1	no	no	INTJ
biomedich-274	105	2	no	no	INTJ
biomedich-274	106	1	no	no	INTJ
biomedich-274	106	2	no	no	INTJ
biomedich-274	106	3	cyp	cyp	ADJ
biomedich-274	106	4	2c9	2c9	NUM
biomedich-274	107	1	no	no	INTJ
biomedich-274	107	2	no	no	INTJ
biomedich-274	107	3	no	no	INTJ
biomedich-274	107	4	no	no	INTJ
biomedich-274	107	5	no	no	INTJ
biomedich-274	107	6	no	no	INTJ
biomedich-274	107	7	no	no	INTJ
biomedich-274	107	8	no	no	INTJ
biomedich-274	107	9	no	no	INTJ
biomedich-274	107	10	no	no	INTJ
biomedich-274	107	11	cyp	cyp	ADJ
biomedich-274	107	12	2d6	2d6	NUM
biomedich-274	108	1	no	no	INTJ
biomedich-274	109	1	no	no	INTJ
biomedich-274	109	2	no	no	INTJ
biomedich-274	109	3	no	no	INTJ
biomedich-274	109	4	no	no	INTJ
biomedich-274	109	5	no	no	INTJ
biomedich-274	109	6	no	no	INTJ
biomedich-274	109	7	no	no	INTJ
biomedich-274	109	8	no	no	INTJ
biomedich-274	110	1	no	no	INTJ
biomedich-274	110	2	cyp	cyp	ADJ
biomedich-274	110	3	3a4	3a4	NUM
biomedich-274	110	4	no	no	INTJ
biomedich-274	111	1	no	no	INTJ
biomedich-274	111	2	no	no	INTJ
biomedich-274	111	3	no	no	INTJ
biomedich-274	111	4	no	no	INTJ
biomedich-274	111	5	no	no	INTJ
biomedich-274	111	6	no	no	INTJ
biomedich-274	111	7	no	no	INTJ
biomedich-274	111	8	no	no	INTJ
biomedich-274	112	1	no	no	DET
biomedich-274	112	2	p	p	NOUN
biomedich-274	112	3	-	-	PUNCT
biomedich-274	112	4	glycoprotein	glycoprotein	NOUN
biomedich-274	113	1	no	no	INTJ
biomedich-274	113	2	no	no	INTJ
biomedich-274	114	1	yes	yes	INTJ
biomedich-274	115	1	yes	yes	INTJ
biomedich-274	116	1	yes	yes	INTJ
biomedich-274	117	1	yes	yes	INTJ
biomedich-274	118	1	no	no	INTJ
biomedich-274	119	1	yes	yes	INTJ
biomedich-274	119	2	yes	yes	INTJ
biomedich-274	120	1	no	no	DET
biomedich-274	120	2	toxicity	toxicity	NOUN
biomedich-274	120	3	mutagenicity	mutagenicity	NOUN
biomedich-274	121	1	no	no	INTJ
biomedich-274	121	2	no	no	INTJ
biomedich-274	121	3	no	no	INTJ
biomedich-274	121	4	no	no	INTJ
biomedich-274	121	5	no	no	INTJ
biomedich-274	121	6	no	no	INTJ
biomedich-274	121	7	no	no	INTJ
biomedich-274	121	8	no	no	INTJ
biomedich-274	121	9	no	no	INTJ
biomedich-274	121	10	no	no	DET
biomedich-274	121	11	tumorgenicity	tumorgenicity	NOUN
biomedich-274	122	1	no	no	INTJ
biomedich-274	122	2	no	no	INTJ
biomedich-274	122	3	no	no	INTJ
biomedich-274	122	4	no	no	INTJ
biomedich-274	122	5	no	no	INTJ
biomedich-274	122	6	no	no	INTJ
biomedich-274	122	7	no	no	INTJ
biomedich-274	122	8	no	no	INTJ
biomedich-274	122	9	no	no	INTJ
biomedich-274	122	10	no	no	INTJ
biomedich-274	122	11	irritant	irritant	ADJ
biomedich-274	122	12	no	no	INTJ
biomedich-274	123	1	no	no	INTJ
biomedich-274	123	2	no	no	INTJ
biomedich-274	123	3	no	no	INTJ
biomedich-274	123	4	no	no	INTJ
biomedich-274	123	5	no	no	INTJ
biomedich-274	124	1	no	no	INTJ
biomedich-274	124	2	no	no	INTJ
biomedich-274	124	3	no	no	INTJ
biomedich-274	124	4	no	no	DET
biomedich-274	124	5	reproductive	reproductive	ADJ
biomedich-274	124	6	effects	effect	NOUN
biomedich-274	125	1	no	no	INTJ
biomedich-274	125	2	no	no	INTJ
biomedich-274	125	3	no	no	INTJ
biomedich-274	125	4	no	no	INTJ
biomedich-274	125	5	no	no	INTJ
biomedich-274	125	6	no	no	INTJ
biomedich-274	125	7	no	no	INTJ
biomedich-274	125	8	no	no	INTJ
biomedich-274	125	9	no	no	INTJ
biomedich-274	125	10	no	no	DET
biomedich-274	125	11	mol	mol	NOUN
biomedich-274	125	12	.	.	PUNCT
biomedich-274	126	1	w	w	PROPN
biomedich-274	126	2	(	(	PUNCT
biomedich-274	126	3	g	g	NOUN
biomedich-274	126	4	/	/	SYM
biomedich-274	126	5	mol	mol	NOUN
biomedich-274	126	6	)	)	PUNCT
biomedich-274	126	7	molecular	molecular	ADJ
biomedich-274	126	8	weight	weight	NOUN
biomedich-274	126	9	,	,	PUNCT
biomedich-274	126	10	h	h	NOUN
biomedich-274	126	11	-	-	PUNCT
biomedich-274	126	12	acc	acc	PROPN
biomedich-274	126	13	hydrogen	hydrogen	NOUN
biomedich-274	126	14	bond	bond	NOUN
biomedich-274	126	15	acceptors	acceptor	NOUN
biomedich-274	126	16	,	,	PUNCT
biomedich-274	126	17	h	h	NOUN
biomedich-274	126	18	-	-	PUNCT
biomedich-274	126	19	don	don	ADJ
biomedich-274	126	20	hydrogen	hydrogen	NOUN
biomedich-274	126	21	bond	bond	NOUN
biomedich-274	126	22	donors	donor	NOUN
biomedich-274	126	23	,	,	PUNCT
biomedich-274	126	24	n.r.b	n.r.b	ADJ
biomedich-274	126	25	number	number	NOUN
biomedich-274	126	26	of	of	ADP
biomedich-274	126	27	rotable	rotable	ADJ
biomedich-274	126	28	bonds	bond	NOUN
biomedich-274	126	29	,	,	PUNCT
biomedich-274	126	30	tpsa	tpsa	NOUN
biomedich-274	126	31	(	(	PUNCT
biomedich-274	126	32	å²	å²	PROPN
biomedich-274	126	33	)	)	PUNCT
biomedich-274	126	34	topological	topological	ADJ
biomedich-274	126	35	polar	polar	ADJ
biomedich-274	126	36	surface	surface	NOUN
biomedich-274	126	37	area	area	NOUN
biomedich-274	126	38	,	,	PUNCT
biomedich-274	126	39	log	log	VERB
biomedich-274	126	40	p	p	NOUN
biomedich-274	126	41	prediction	prediction	NOUN
biomedich-274	126	42	of	of	ADP
biomedich-274	126	43	octanol	octanol	NOUN
biomedich-274	126	44	/	/	SYM
biomedich-274	126	45	water	water	NOUN
biomedich-274	126	46	partition	partition	NOUN
biomedich-274	126	47	coefficient	coefficient	NOUN
biomedich-274	126	48	,	,	PUNCT
biomedich-274	126	49	b.sc	b.sc	PROPN
biomedich-274	126	50	bioavailability	bioavailability	NOUN
biomedich-274	126	51	score	score	NOUN
biomedich-274	126	52	,	,	PUNCT
biomedich-274	126	53	d.l.s	d.l.s	X
biomedich-274	126	54	druglikeness	druglikeness	NOUN
biomedich-274	126	55	score	score	NOUN
biomedich-274	126	56	,	,	PUNCT
biomedich-274	126	57	n.l.v	n.l.v	DET
biomedich-274	126	58	number	number	NOUN
biomedich-274	126	59	of	of	ADP
biomedich-274	126	60	lipinski	lipinski	PROPN
biomedich-274	126	61	’s	’s	PART
biomedich-274	126	62	rule	rule	NOUN
biomedich-274	126	63	violations	violation	NOUN
biomedich-274	126	64	,	,	PUNCT
biomedich-274	126	65	cyp	cyp	ADJ
biomedich-274	126	66	cytochrome	cytochrome	NOUN
biomedich-274	126	67	p-450	p-450	NOUN
biomedich-274	126	68	enzyme	enzyme	NOUN
biomedich-274	126	69	.	.	PUNCT
biomedich-274	127	1	ibrahim	ibrahim	PROPN
biomedich-274	127	2	&	&	CCONJ
biomedich-274	127	3	ul	ul	PROPN
biomedich-274	127	4	haq	haq	PROPN
biomedich-274	127	5	–	–	PUNCT
biomedich-274	127	6	flavone	flavone	NOUN
biomedich-274	127	7	glycosides	glycoside	NOUN
biomedich-274	127	8	attenuate	attenuate	VERB
biomedich-274	127	9	covid-19	covid-19	PROPN
biomedich-274	127	10	105	105	NUM
biomedich-274	127	11	molecular	molecular	ADJ
biomedich-274	127	12	dynamics	dynamic	NOUN
biomedich-274	127	13	simulation	simulation	NOUN
biomedich-274	127	14	the	the	DET
biomedich-274	127	15	molecular	molecular	ADJ
biomedich-274	127	16	dynamics	dynamic	NOUN
biomedich-274	127	17	simulation	simulation	NOUN
biomedich-274	127	18	is	be	AUX
biomedich-274	127	19	performed	perform	VERB
biomedich-274	127	20	to	to	PART
biomedich-274	127	21	assess	assess	VERB
biomedich-274	127	22	the	the	DET
biomedich-274	127	23	physical	physical	ADJ
biomedich-274	127	24	dynamics	dynamic	NOUN
biomedich-274	127	25	or	or	CCONJ
biomedich-274	127	26	motions	motion	NOUN
biomedich-274	127	27	of	of	ADP
biomedich-274	127	28	a	a	DET
biomedich-274	127	29	molecule	molecule	NOUN
biomedich-274	127	30	,	,	PUNCT
biomedich-274	127	31	virtually	virtually	ADV
biomedich-274	127	32	on	on	ADP
biomedich-274	127	33	a	a	DET
biomedich-274	127	34	computer	computer	NOUN
biomedich-274	127	35	which	which	PRON
biomedich-274	127	36	imparts	impart	VERB
biomedich-274	127	37	a	a	DET
biomedich-274	127	38	lot	lot	NOUN
biomedich-274	127	39	of	of	ADP
biomedich-274	127	40	details	detail	NOUN
biomedich-274	127	41	and	and	CCONJ
biomedich-274	127	42	facts	fact	NOUN
biomedich-274	127	43	about	about	ADP
biomedich-274	127	44	motions	motion	NOUN
biomedich-274	127	45	and	and	CCONJ
biomedich-274	127	46	gestures	gesture	NOUN
biomedich-274	127	47	of	of	ADP
biomedich-274	127	48	a	a	DET
biomedich-274	127	49	given	give	VERB
biomedich-274	127	50	docked	docked	ADJ
biomedich-274	127	51	macromolecule	macromolecule	NOUN
biomedich-274	127	52	complex	complex	NOUN
biomedich-274	127	53	.	.	PUNCT
biomedich-274	128	1	the	the	DET
biomedich-274	128	2	molecular	molecular	ADJ
biomedich-274	128	3	dynamics	dynamic	NOUN
biomedich-274	128	4	simulation	simulation	NOUN
biomedich-274	128	5	for	for	ADP
biomedich-274	128	6	the	the	DET
biomedich-274	128	7	top	top	ADJ
biomedich-274	128	8	docked	docked	ADJ
biomedich-274	128	9	complex	complex	NOUN
biomedich-274	128	10	of	of	ADP
biomedich-274	128	11	diosmin	diosmin	NOUN
biomedich-274	128	12	(	(	PUNCT
biomedich-274	128	13	l5	l5	PROPN
biomedich-274	128	14	)	)	PUNCT
biomedich-274	128	15	was	be	AUX
biomedich-274	128	16	conducted	conduct	VERB
biomedich-274	128	17	using	use	VERB
biomedich-274	128	18	imods	imod	NOUN
biomedich-274	128	19	server	server	NOUN
biomedich-274	128	20	(	(	PUNCT
biomedich-274	128	21	lopéz	lopéz	NOUN
biomedich-274	128	22	-	-	PUNCT
biomedich-274	128	23	blanco	blanco	PROPN
biomedich-274	128	24	,	,	PUNCT
biomedich-274	128	25	garzón	garzón	NOUN
biomedich-274	128	26	,	,	PUNCT
biomedich-274	128	27	and	and	CCONJ
biomedich-274	128	28	chacón	chacón	PROPN
biomedich-274	128	29	2011	2011	NUM
biomedich-274	128	30	)	)	PUNCT
biomedich-274	128	31	.	.	PUNCT
biomedich-274	129	1	the	the	DET
biomedich-274	129	2	molecular	molecular	ADJ
biomedich-274	129	3	dynamics	dynamic	NOUN
biomedich-274	129	4	simulation	simulation	NOUN
biomedich-274	129	5	was	be	AUX
biomedich-274	129	6	carried	carry	VERB
biomedich-274	129	7	upon	upon	SCONJ
biomedich-274	129	8	normal	normal	ADJ
biomedich-274	129	9	mode	mode	NOUN
biomedich-274	129	10	analysis	analysis	NOUN
biomedich-274	129	11	(	(	PUNCT
biomedich-274	129	12	nma	nma	PROPN
biomedich-274	129	13	)	)	PUNCT
biomedich-274	129	14	.	.	PUNCT
biomedich-274	130	1	the	the	DET
biomedich-274	130	2	results	result	NOUN
biomedich-274	130	3	for	for	ADP
biomedich-274	130	4	b	b	NOUN
biomedich-274	130	5	-	-	PUNCT
biomedich-274	130	6	factor	factor	NOUN
biomedich-274	130	7	or	or	CCONJ
biomedich-274	130	8	mobility	mobility	NOUN
biomedich-274	130	9	were	be	AUX
biomedich-274	130	10	imparted	impart	VERB
biomedich-274	130	11	.	.	PUNCT
biomedich-274	131	1	this	this	PRON
biomedich-274	131	2	is	be	AUX
biomedich-274	131	3	an	an	DET
biomedich-274	131	4	important	important	ADJ
biomedich-274	131	5	factor	factor	NOUN
biomedich-274	131	6	of	of	ADP
biomedich-274	131	7	the	the	DET
biomedich-274	131	8	protein	protein	NOUN
biomedich-274	131	9	crystallography	crystallography	NOUN
biomedich-274	131	10	,	,	PUNCT
biomedich-274	131	11	which	which	PRON
biomedich-274	131	12	specifies	specify	VERB
biomedich-274	131	13	the	the	DET
biomedich-274	131	14	residues	residue	NOUN
biomedich-274	131	15	with	with	ADP
biomedich-274	131	16	in	in	ADP
biomedich-274	131	17	the	the	DET
biomedich-274	131	18	complex	complex	NOUN
biomedich-274	131	19	that	that	PRON
biomedich-274	131	20	deform	deform	VERB
biomedich-274	131	21	themselves	themselves	PRON
biomedich-274	131	22	to	to	PART
biomedich-274	131	23	interact	interact	VERB
biomedich-274	131	24	with	with	ADP
biomedich-274	131	25	other	other	ADJ
biomedich-274	131	26	residues	residue	NOUN
biomedich-274	131	27	,	,	PUNCT
biomedich-274	131	28	exposing	expose	VERB
biomedich-274	131	29	the	the	DET
biomedich-274	131	30	flexibility	flexibility	NOUN
biomedich-274	131	31	of	of	ADP
biomedich-274	131	32	a	a	DET
biomedich-274	131	33	molecule	molecule	NOUN
biomedich-274	131	34	.	.	PUNCT
biomedich-274	132	1	the	the	DET
biomedich-274	132	2	arrow	arrow	NOUN
biomedich-274	132	3	field	field	NOUN
biomedich-274	132	4	around	around	ADP
biomedich-274	132	5	the	the	DET
biomedich-274	132	6	complex	complex	NOUN
biomedich-274	132	7	shows	show	VERB
biomedich-274	132	8	the	the	DET
biomedich-274	132	9	orientation	orientation	NOUN
biomedich-274	132	10	of	of	ADP
biomedich-274	132	11	our	our	PRON
biomedich-274	132	12	complexed	complexed	NOUN
biomedich-274	132	13	macromolecule	macromolecule	NOUN
biomedich-274	132	14	virtually	virtually	ADV
biomedich-274	132	15	,	,	PUNCT
biomedich-274	132	16	as	as	SCONJ
biomedich-274	132	17	shown	show	VERB
biomedich-274	132	18	in	in	ADP
biomedich-274	132	19	the	the	DET
biomedich-274	132	20	figure	figure	NOUN
biomedich-274	132	21	6	6	NUM
biomedich-274	132	22	.	.	PUNCT
biomedich-274	132	23	figure	figure	NOUN
biomedich-274	132	24	6	6	NUM
biomedich-274	132	25	.	.	PUNCT
biomedich-274	133	1	the	the	DET
biomedich-274	133	2	figure	figure	NOUN
biomedich-274	133	3	shows	show	VERB
biomedich-274	133	4	the	the	DET
biomedich-274	133	5	diagrammatic	diagrammatic	ADJ
biomedich-274	133	6	results	result	NOUN
biomedich-274	133	7	of	of	ADP
biomedich-274	133	8	the	the	DET
biomedich-274	133	9	molecular	molecular	ADJ
biomedich-274	133	10	dynamics	dynamic	NOUN
biomedich-274	133	11	simulation	simulation	NOUN
biomedich-274	133	12	done	do	VERB
biomedich-274	133	13	with	with	ADP
biomedich-274	133	14	the	the	DET
biomedich-274	133	15	best	well	ADV
biomedich-274	133	16	docked	docked	ADJ
biomedich-274	133	17	complex	complex	ADJ
biomedich-274	133	18	,	,	PUNCT
biomedich-274	133	19	diosmin	diosmin	NOUN
biomedich-274	133	20	(	(	PUNCT
biomedich-274	133	21	l5	l5	PROPN
biomedich-274	133	22	)	)	PUNCT
biomedich-274	133	23	with	with	ADP
biomedich-274	133	24	ace2	ace2	PROPN
biomedich-274	133	25	protein	protein	NOUN
biomedich-274	133	26	.	.	PUNCT
biomedich-274	134	1	image	image	NOUN
biomedich-274	134	2	(	(	PUNCT
biomedich-274	134	3	a	a	X
biomedich-274	134	4	)	)	PUNCT
biomedich-274	134	5	shows	show	VERB
biomedich-274	134	6	the	the	DET
biomedich-274	134	7	orientation	orientation	NOUN
biomedich-274	134	8	of	of	ADP
biomedich-274	134	9	the	the	DET
biomedich-274	134	10	docked	docked	ADJ
biomedich-274	134	11	complex	complex	NOUN
biomedich-274	134	12	with	with	ADP
biomedich-274	134	13	the	the	DET
biomedich-274	134	14	arrow	arrow	NOUN
biomedich-274	134	15	field	field	NOUN
biomedich-274	134	16	.	.	PUNCT
biomedich-274	135	1	image	image	NOUN
biomedich-274	135	2	(	(	PUNCT
biomedich-274	135	3	b	b	NOUN
biomedich-274	135	4	)	)	PUNCT
biomedich-274	135	5	shows	show	VERB
biomedich-274	135	6	the	the	DET
biomedich-274	135	7	deformability	deformability	NOUN
biomedich-274	135	8	graph	graph	NOUN
biomedich-274	135	9	and	and	CCONJ
biomedich-274	135	10	graphical	graphical	ADJ
biomedich-274	135	11	representation	representation	NOUN
biomedich-274	135	12	of	of	ADP
biomedich-274	135	13	the	the	DET
biomedich-274	135	14	b	b	NOUN
biomedich-274	135	15	-	-	PUNCT
biomedich-274	135	16	factor	factor	NOUN
biomedich-274	135	17	.	.	PUNCT
biomedich-274	136	1	eigenvalue	eigenvalue	PROPN
biomedich-274	136	2	was	be	AUX
biomedich-274	136	3	also	also	ADV
biomedich-274	136	4	yielded	yield	VERB
biomedich-274	136	5	through	through	ADP
biomedich-274	136	6	this	this	DET
biomedich-274	136	7	server	server	NOUN
biomedich-274	136	8	that	that	PRON
biomedich-274	136	9	denotes	denote	VERB
biomedich-274	136	10	the	the	DET
biomedich-274	136	11	energy	energy	NOUN
biomedich-274	136	12	required	require	VERB
biomedich-274	136	13	for	for	ADP
biomedich-274	136	14	deforming	deform	VERB
biomedich-274	136	15	a	a	DET
biomedich-274	136	16	residue	residue	NOUN
biomedich-274	136	17	in	in	ADP
biomedich-274	136	18	a	a	DET
biomedich-274	136	19	dynamic	dynamic	ADJ
biomedich-274	136	20	protein	protein	NOUN
biomedich-274	136	21	for	for	ADP
biomedich-274	136	22	interaction	interaction	NOUN
biomedich-274	136	23	with	with	ADP
biomedich-274	136	24	other	other	ADJ
biomedich-274	136	25	residues	residue	NOUN
biomedich-274	136	26	.	.	PUNCT
biomedich-274	137	1	the	the	DET
biomedich-274	137	2	less	less	ADJ
biomedich-274	137	3	is	be	AUX
biomedich-274	137	4	the	the	DET
biomedich-274	137	5	eigenvalue	eigenvalue	NOUN
biomedich-274	137	6	,	,	PUNCT
biomedich-274	137	7	the	the	DET
biomedich-274	137	8	more	more	ADV
biomedich-274	137	9	is	be	AUX
biomedich-274	137	10	the	the	DET
biomedich-274	137	11	ease	ease	NOUN
biomedich-274	137	12	for	for	ADP
biomedich-274	137	13	deformation	deformation	NOUN
biomedich-274	137	14	of	of	ADP
biomedich-274	137	15	the	the	DET
biomedich-274	137	16	residues	residue	NOUN
biomedich-274	137	17	.	.	PUNCT
biomedich-274	138	1	the	the	DET
biomedich-274	138	2	eigenvalue	eigenvalue	NOUN
biomedich-274	138	3	of	of	ADP
biomedich-274	138	4	the	the	DET
biomedich-274	138	5	studied	study	VERB
biomedich-274	138	6	complex	complex	NOUN
biomedich-274	138	7	was	be	AUX
biomedich-274	138	8	5.6245e-05	5.6245e-05	NUM
biomedich-274	138	9	.	.	PUNCT
biomedich-274	138	10	covariance	covariance	NOUN
biomedich-274	138	11	map	map	NOUN
biomedich-274	138	12	casts	cast	VERB
biomedich-274	138	13	a	a	DET
biomedich-274	138	14	scenario	scenario	NOUN
biomedich-274	138	15	of	of	ADP
biomedich-274	138	16	interactions	interaction	NOUN
biomedich-274	138	17	between	between	ADP
biomedich-274	138	18	the	the	DET
biomedich-274	138	19	residues	residue	NOUN
biomedich-274	138	20	of	of	ADP
biomedich-274	138	21	the	the	DET
biomedich-274	138	22	protein	protein	NOUN
biomedich-274	138	23	and	and	CCONJ
biomedich-274	138	24	ligand	ligand	VERB
biomedich-274	138	25	in	in	ADP
biomedich-274	138	26	the	the	DET
biomedich-274	138	27	complex	complex	NOUN
biomedich-274	138	28	while	while	SCONJ
biomedich-274	138	29	the	the	DET
biomedich-274	138	30	elastic	elastic	ADJ
biomedich-274	138	31	network	network	NOUN
biomedich-274	138	32	deliver	deliver	VERB
biomedich-274	138	33	a	a	DET
biomedich-274	138	34	complete	complete	ADJ
biomedich-274	138	35	picture	picture	NOUN
biomedich-274	138	36	of	of	ADP
biomedich-274	138	37	the	the	DET
biomedich-274	138	38	stiffness	stiffness	NOUN
biomedich-274	138	39	within	within	ADP
biomedich-274	138	40	the	the	DET
biomedich-274	138	41	target	target	NOUN
biomedich-274	138	42	molecule	molecule	NOUN
biomedich-274	138	43	,	,	PUNCT
biomedich-274	138	44	hence	hence	ADV
biomedich-274	138	45	giving	give	VERB
biomedich-274	138	46	an	an	DET
biomedich-274	138	47	estimate	estimate	NOUN
biomedich-274	138	48	of	of	ADP
biomedich-274	138	49	deforming	deform	VERB
biomedich-274	138	50	in	in	ADP
biomedich-274	138	51	the	the	DET
biomedich-274	138	52	residues	residue	NOUN
biomedich-274	138	53	of	of	ADP
biomedich-274	138	54	the	the	DET
biomedich-274	138	55	target	target	NOUN
biomedich-274	138	56	protein	protein	NOUN
biomedich-274	138	57	,	,	PUNCT
biomedich-274	138	58	as	as	SCONJ
biomedich-274	138	59	provided	provide	VERB
biomedich-274	138	60	in	in	ADP
biomedich-274	138	61	figure	figure	NOUN
biomedich-274	138	62	7	7	NUM
biomedich-274	138	63	.	.	PUNCT
biomedich-274	138	64	figure	figure	VERB
biomedich-274	138	65	7	7	NUM
biomedich-274	138	66	.	.	PUNCT
biomedich-274	138	67	image	image	NOUN
biomedich-274	138	68	(	(	PUNCT
biomedich-274	138	69	a	a	X
biomedich-274	138	70	)	)	PUNCT
biomedich-274	138	71	demonstrates	demonstrate	VERB
biomedich-274	138	72	the	the	DET
biomedich-274	138	73	covariance	covariance	NOUN
biomedich-274	138	74	graph	graph	NOUN
biomedich-274	138	75	of	of	ADP
biomedich-274	138	76	the	the	DET
biomedich-274	138	77	best	well	ADV
biomedich-274	138	78	docked	docked	ADJ
biomedich-274	138	79	complex	complex	ADJ
biomedich-274	138	80	diosmin	diosmin	NOUN
biomedich-274	138	81	(	(	PUNCT
biomedich-274	138	82	l5	l5	PROPN
biomedich-274	138	83	)	)	PUNCT
biomedich-274	138	84	and	and	CCONJ
biomedich-274	138	85	ace2	ace2	PROPN
biomedich-274	138	86	protein	protein	NOUN
biomedich-274	138	87	,	,	PUNCT
biomedich-274	138	88	image	image	NOUN
biomedich-274	138	89	(	(	PUNCT
biomedich-274	138	90	b	b	NOUN
biomedich-274	138	91	)	)	PUNCT
biomedich-274	138	92	represents	represent	VERB
biomedich-274	138	93	the	the	DET
biomedich-274	138	94	elastic	elastic	ADJ
biomedich-274	138	95	network	network	NOUN
biomedich-274	138	96	map	map	NOUN
biomedich-274	138	97	of	of	ADP
biomedich-274	138	98	the	the	DET
biomedich-274	138	99	docked	dock	VERB
biomedich-274	138	100	ligand	ligand	NOUN
biomedich-274	138	101	while	while	SCONJ
biomedich-274	138	102	image	image	NOUN
biomedich-274	138	103	(	(	PUNCT
biomedich-274	138	104	c	c	NOUN
biomedich-274	138	105	)	)	PUNCT
biomedich-274	138	106	represents	represent	VERB
biomedich-274	138	107	the	the	DET
biomedich-274	138	108	eigenvalue	eigenvalue	NOUN
biomedich-274	138	109	of	of	ADP
biomedich-274	138	110	the	the	DET
biomedich-274	138	111	docked	docked	ADJ
biomedich-274	138	112	ligand	ligand	NOUN
biomedich-274	138	113	.	.	PUNCT
biomedich-274	139	1	106	106	NUM
biomedich-274	139	2	biology	biology	NOUN
biomedich-274	139	3	,	,	PUNCT
biomedich-274	139	4	medicine	medicine	NOUN
biomedich-274	139	5	,	,	PUNCT
biomedich-274	139	6	&	&	CCONJ
biomedich-274	139	7	natural	natural	ADJ
biomedich-274	139	8	product	product	NOUN
biomedich-274	139	9	chemistry	chemistry	NOUN
biomedich-274	139	10	12	12	NUM
biomedich-274	139	11	(	(	PUNCT
biomedich-274	139	12	1	1	NUM
biomedich-274	139	13	)	)	PUNCT
biomedich-274	139	14	,	,	PUNCT
biomedich-274	139	15	2023	2023	NUM
biomedich-274	139	16	:	:	PUNCT
biomedich-274	139	17	97	97	NUM
biomedich-274	139	18	-	-	SYM
biomedich-274	139	19	108	108	NUM
biomedich-274	139	20	discussion	discussion	NOUN
biomedich-274	139	21	molecular	molecular	ADJ
biomedich-274	139	22	docking	docking	NOUN
biomedich-274	139	23	is	be	AUX
biomedich-274	139	24	a	a	DET
biomedich-274	139	25	worthwhile	worthwhile	ADJ
biomedich-274	139	26	tool	tool	NOUN
biomedich-274	139	27	in	in	ADP
biomedich-274	139	28	the	the	DET
biomedich-274	139	29	drug	drug	NOUN
biomedich-274	139	30	discovery	discovery	NOUN
biomedich-274	139	31	and	and	CCONJ
biomedich-274	139	32	repurposing	repurpose	VERB
biomedich-274	139	33	phenomenon	phenomenon	NOUN
biomedich-274	139	34	in	in	ADP
biomedich-274	139	35	the	the	DET
biomedich-274	139	36	arena	arena	NOUN
biomedich-274	139	37	of	of	ADP
biomedich-274	139	38	computer	computer	NOUN
biomedich-274	139	39	aided	aid	VERB
biomedich-274	139	40	drug	drug	NOUN
biomedich-274	139	41	designing	designing	NOUN
biomedich-274	139	42	(	(	PUNCT
biomedich-274	139	43	hughes	hughe	NOUN
biomedich-274	139	44	et	et	PROPN
biomedich-274	139	45	al	al	PROPN
biomedich-274	139	46	.	.	PROPN
biomedich-274	139	47	2011	2011	NUM
biomedich-274	139	48	)	)	PUNCT
biomedich-274	139	49	.	.	PUNCT
biomedich-274	140	1	the	the	DET
biomedich-274	140	2	interaction	interaction	NOUN
biomedich-274	140	3	of	of	ADP
biomedich-274	140	4	a	a	DET
biomedich-274	140	5	specific	specific	ADJ
biomedich-274	140	6	compound	compound	NOUN
biomedich-274	140	7	with	with	ADP
biomedich-274	140	8	a	a	DET
biomedich-274	140	9	specific	specific	ADJ
biomedich-274	140	10	target	target	NOUN
biomedich-274	140	11	molecule	molecule	NOUN
biomedich-274	140	12	is	be	AUX
biomedich-274	140	13	predicted	predict	VERB
biomedich-274	140	14	computationally	computationally	ADV
biomedich-274	140	15	,	,	PUNCT
biomedich-274	140	16	without	without	ADP
biomedich-274	140	17	utilizing	utilize	VERB
biomedich-274	140	18	the	the	DET
biomedich-274	140	19	wet	wet	ADJ
biomedich-274	140	20	lab	lab	NOUN
biomedich-274	140	21	(	(	PUNCT
biomedich-274	140	22	meng	meng	PROPN
biomedich-274	140	23	et	et	PROPN
biomedich-274	140	24	al	al	PROPN
biomedich-274	140	25	.	.	PROPN
biomedich-274	140	26	2011	2011	NUM
biomedich-274	140	27	)	)	PUNCT
biomedich-274	140	28	.	.	PUNCT
biomedich-274	141	1	in	in	ADP
biomedich-274	141	2	this	this	DET
biomedich-274	141	3	study	study	NOUN
biomedich-274	141	4	,	,	PUNCT
biomedich-274	141	5	molecular	molecular	ADJ
biomedich-274	141	6	docking	docking	NOUN
biomedich-274	141	7	was	be	AUX
biomedich-274	141	8	used	use	VERB
biomedich-274	141	9	to	to	PART
biomedich-274	141	10	recognize	recognize	VERB
biomedich-274	141	11	the	the	DET
biomedich-274	141	12	potential	potential	ADJ
biomedich-274	141	13	inhibition	inhibition	NOUN
biomedich-274	141	14	of	of	ADP
biomedich-274	141	15	ace2	ace2	NOUN
biomedich-274	141	16	enzyme	enzyme	NOUN
biomedich-274	141	17	by	by	ADP
biomedich-274	141	18	flavone	flavone	NOUN
biomedich-274	141	19	glycosides	glycoside	NOUN
biomedich-274	141	20	.	.	PUNCT
biomedich-274	142	1	in	in	ADP
biomedich-274	142	2	this	this	DET
biomedich-274	142	3	study	study	NOUN
biomedich-274	142	4	,	,	PUNCT
biomedich-274	142	5	it	it	PRON
biomedich-274	142	6	was	be	AUX
biomedich-274	142	7	observed	observe	VERB
biomedich-274	142	8	that	that	SCONJ
biomedich-274	142	9	flavone	flavone	NOUN
biomedich-274	142	10	glycosides	glycoside	NOUN
biomedich-274	142	11	had	have	VERB
biomedich-274	142	12	an	an	DET
biomedich-274	142	13	appreciable	appreciable	ADJ
biomedich-274	142	14	range	range	NOUN
biomedich-274	142	15	of	of	ADP
biomedich-274	142	16	binding	bind	VERB
biomedich-274	142	17	affinities	affinity	NOUN
biomedich-274	142	18	with	with	ADP
biomedich-274	142	19	the	the	DET
biomedich-274	142	20	active	active	ADJ
biomedich-274	142	21	site	site	NOUN
biomedich-274	142	22	residues	residue	NOUN
biomedich-274	142	23	of	of	ADP
biomedich-274	142	24	ace2	ace2	NOUN
biomedich-274	142	25	enzyme	enzyme	NOUN
biomedich-274	142	26	i.e.	i.e.	X
biomedich-274	142	27	-9.3	-9.3	NOUN
biomedich-274	142	28	to	to	PART
biomedich-274	142	29	-7.1	-7.1	PUNCT
biomedich-274	142	30	kcal	kcal	PROPN
biomedich-274	142	31	/	/	SYM
biomedich-274	142	32	mol	mol	PROPN
biomedich-274	142	33	.	.	PUNCT
biomedich-274	143	1	the	the	DET
biomedich-274	143	2	potential	potential	ADJ
biomedich-274	143	3	drug	drug	NOUN
biomedich-274	143	4	candidates	candidate	NOUN
biomedich-274	143	5	exhibited	exhibit	VERB
biomedich-274	143	6	their	their	PRON
biomedich-274	143	7	powerful	powerful	ADJ
biomedich-274	143	8	interactions	interaction	NOUN
biomedich-274	143	9	with	with	ADP
biomedich-274	143	10	the	the	DET
biomedich-274	143	11	active	active	ADJ
biomedich-274	143	12	residues	residue	NOUN
biomedich-274	143	13	of	of	ADP
biomedich-274	143	14	ace2	ace2	NOUN
biomedich-274	143	15	i.e.	i.e.	X
biomedich-274	143	16	his	his	PRON
biomedich-274	143	17	378	378	NUM
biomedich-274	143	18	,	,	PUNCT
biomedich-274	143	19	his	his	PRON
biomedich-274	143	20	401	401	NUM
biomedich-274	143	21	and	and	CCONJ
biomedich-274	143	22	glu	glu	NOUN
biomedich-274	143	23	402	402	NUM
biomedich-274	143	24	.	.	PUNCT
biomedich-274	144	1	luteolin	luteolin	PROPN
biomedich-274	144	2	3'-glucoside	3'-glucoside	ADV
biomedich-274	144	3	(	(	PUNCT
biomedich-274	144	4	l1	l1	PROPN
biomedich-274	144	5	)	)	PUNCT
biomedich-274	144	6	showed	show	VERB
biomedich-274	144	7	binding	binding	ADJ
biomedich-274	144	8	energy	energy	NOUN
biomedich-274	144	9	of	of	ADP
biomedich-274	144	10	-7.5	-7.5	ADJ
biomedich-274	144	11	kcal	kcal	PROPN
biomedich-274	144	12	/	/	SYM
biomedich-274	144	13	mol	mol	PROPN
biomedich-274	144	14	,	,	PUNCT
biomedich-274	144	15	that	that	PRON
biomedich-274	144	16	is	be	AUX
biomedich-274	144	17	highly	highly	ADV
biomedich-274	144	18	encouraging	encouraging	ADJ
biomedich-274	144	19	for	for	ADP
biomedich-274	144	20	inhibition	inhibition	NOUN
biomedich-274	144	21	of	of	ADP
biomedich-274	144	22	ace2	ace2	NOUN
biomedich-274	144	23	.	.	PUNCT
biomedich-274	145	1	luteolin	luteolin	PROPN
biomedich-274	145	2	3'glucoside	3'glucoside	NUM
biomedich-274	145	3	(	(	PUNCT
biomedich-274	145	4	l1	l1	PROPN
biomedich-274	145	5	)	)	PUNCT
biomedich-274	145	6	,	,	PUNCT
biomedich-274	145	7	isolated	isolate	VERB
biomedich-274	145	8	from	from	ADP
biomedich-274	145	9	podocarpus	podocarpus	ADJ
biomedich-274	145	10	nivalis	nivali	NOUN
biomedich-274	145	11	(	(	PUNCT
biomedich-274	145	12	“	"	PUNCT
biomedich-274	145	13	luteolin	luteolin	PROPN
biomedich-274	145	14	3’-glucoside	3’-glucoside	NUM
biomedich-274	145	15	|	|	ADV
biomedich-274	145	16	c21h20o11	c21h20o11	PROPN
biomedich-274	145	17	pubchem	pubchem	NOUN
biomedich-274	145	18	”	"	PUNCT
biomedich-274	145	19	n.d	n.d	PROPN
biomedich-274	145	20	.	.	PROPN
biomedich-274	145	21	)	)	PUNCT
biomedich-274	145	22	has	have	AUX
biomedich-274	145	23	also	also	ADV
biomedich-274	145	24	been	be	AUX
biomedich-274	145	25	identified	identify	VERB
biomedich-274	145	26	as	as	ADP
biomedich-274	145	27	hepatoprotective	hepatoprotective	ADJ
biomedich-274	145	28	and	and	CCONJ
biomedich-274	145	29	immunoregulatory	immunoregulatory	ADJ
biomedich-274	145	30	agent	agent	NOUN
biomedich-274	145	31	in	in	ADP
biomedich-274	145	32	some	some	DET
biomedich-274	145	33	studies	study	NOUN
biomedich-274	145	34	(	(	PUNCT
biomedich-274	145	35	park	park	NOUN
biomedich-274	145	36	and	and	CCONJ
biomedich-274	145	37	song	song	NOUN
biomedich-274	145	38	2019	2019	NUM
biomedich-274	145	39	)	)	PUNCT
biomedich-274	145	40	.	.	PUNCT
biomedich-274	146	1	isovitexin	isovitexin	NOUN
biomedich-274	146	2	(	(	PUNCT
biomedich-274	146	3	l2	l2	NOUN
biomedich-274	146	4	)	)	PUNCT
biomedich-274	146	5	,	,	PUNCT
biomedich-274	146	6	acquired	acquire	VERB
biomedich-274	146	7	from	from	ADP
biomedich-274	146	8	carex	carex	PROPN
biomedich-274	146	9	fraseriana	fraseriana	PROPN
biomedich-274	146	10	(	(	PUNCT
biomedich-274	146	11	“	"	PUNCT
biomedich-274	146	12	isovitexin	isovitexin	NOUN
biomedich-274	146	13	|	|	ADV
biomedich-274	146	14	c21h20o10	c21h20o10	VERB
biomedich-274	146	15	pubchem	pubchem	NOUN
biomedich-274	146	16	”	"	PUNCT
biomedich-274	146	17	n.d	n.d	PROPN
biomedich-274	146	18	.	.	PROPN
biomedich-274	146	19	)	)	PUNCT
biomedich-274	146	20	,	,	PUNCT
biomedich-274	146	21	also	also	ADV
biomedich-274	146	22	spotted	spot	VERB
biomedich-274	146	23	for	for	ADP
biomedich-274	146	24	its	its	PRON
biomedich-274	146	25	anti	anti	ADJ
biomedich-274	146	26	-	-	ADJ
biomedich-274	146	27	inflammatory	inflammatory	ADJ
biomedich-274	146	28	and	and	CCONJ
biomedich-274	146	29	antidiabetic	antidiabetic	ADJ
biomedich-274	146	30	potential	potential	NOUN
biomedich-274	146	31	(	(	PUNCT
biomedich-274	146	32	abdulai	abdulai	PROPN
biomedich-274	146	33	et	et	PROPN
biomedich-274	146	34	al	al	PROPN
biomedich-274	146	35	.	.	PROPN
biomedich-274	146	36	2021	2021	NUM
biomedich-274	146	37	)	)	PUNCT
biomedich-274	146	38	,	,	PUNCT
biomedich-274	146	39	has	have	AUX
biomedich-274	146	40	provided	provide	VERB
biomedich-274	146	41	very	very	ADV
biomedich-274	146	42	optimistic	optimistic	ADJ
biomedich-274	146	43	results	result	NOUN
biomedich-274	146	44	regarding	regard	VERB
biomedich-274	146	45	binding	bind	VERB
biomedich-274	146	46	and	and	CCONJ
biomedich-274	146	47	potential	potential	ADJ
biomedich-274	146	48	inhibition	inhibition	NOUN
biomedich-274	146	49	of	of	ADP
biomedich-274	146	50	ace2	ace2	NOUN
biomedich-274	146	51	.	.	PUNCT
biomedich-274	147	1	a	a	DET
biomedich-274	147	2	reasonable	reasonable	ADJ
biomedich-274	147	3	binding	bind	VERB
biomedich-274	147	4	energy	energy	NOUN
biomedich-274	147	5	of	of	ADP
biomedich-274	147	6	-7.1	-7.1	INTJ
biomedich-274	147	7	kcal	kcal	NOUN
biomedich-274	147	8	/	/	SYM
biomedich-274	147	9	mol	mol	NOUN
biomedich-274	147	10	and	and	CCONJ
biomedich-274	147	11	linkages	linkage	NOUN
biomedich-274	147	12	with	with	ADP
biomedich-274	147	13	active	active	ADJ
biomedich-274	147	14	residues	residue	NOUN
biomedich-274	147	15	can	can	AUX
biomedich-274	147	16	make	make	VERB
biomedich-274	147	17	a	a	DET
biomedich-274	147	18	considerable	considerable	ADJ
biomedich-274	147	19	molecule	molecule	NOUN
biomedich-274	147	20	having	have	VERB
biomedich-274	147	21	potential	potential	ADJ
biomedich-274	147	22	inhibitory	inhibitory	ADJ
biomedich-274	147	23	activity	activity	NOUN
biomedich-274	147	24	for	for	ADP
biomedich-274	147	25	ace2	ace2	NOUN
biomedich-274	147	26	.	.	PUNCT
biomedich-274	148	1	baicalin	baicalin	PROPN
biomedich-274	148	2	(	(	PUNCT
biomedich-274	148	3	l3	l3	PROPN
biomedich-274	148	4	)	)	PUNCT
biomedich-274	148	5	is	be	AUX
biomedich-274	148	6	a	a	DET
biomedich-274	148	7	flavone	flavone	NOUN
biomedich-274	148	8	glycoside	glycoside	NOUN
biomedich-274	148	9	derived	derive	VERB
biomedich-274	148	10	from	from	ADP
biomedich-274	148	11	scutellaria	scutellaria	NOUN
biomedich-274	148	12	amoena	amoena	NOUN
biomedich-274	148	13	(	(	PUNCT
biomedich-274	148	14	“	"	PUNCT
biomedich-274	148	15	baicalin	baicalin	NOUN
biomedich-274	148	16	|	|	ADV
biomedich-274	148	17	c21h18o11	c21h18o11	PROPN
biomedich-274	148	18	pubchem	pubchem	NOUN
biomedich-274	148	19	”	"	PUNCT
biomedich-274	148	20	n.d	n.d	PROPN
biomedich-274	148	21	.	.	PROPN
biomedich-274	148	22	)	)	PUNCT
biomedich-274	148	23	,	,	PUNCT
biomedich-274	148	24	has	have	VERB
biomedich-274	148	25	anti	anti	ADJ
biomedich-274	148	26	-	-	ADJ
biomedich-274	148	27	inflammatory	inflammatory	ADJ
biomedich-274	148	28	effects	effect	NOUN
biomedich-274	148	29	in	in	ADP
biomedich-274	148	30	cardiovascular	cardiovascular	ADJ
biomedich-274	148	31	,	,	PUNCT
biomedich-274	148	32	neurodegenerative	neurodegenerative	ADJ
biomedich-274	148	33	and	and	CCONJ
biomedich-274	148	34	infectious	infectious	ADJ
biomedich-274	148	35	ailments	ailment	NOUN
biomedich-274	148	36	(	(	PUNCT
biomedich-274	148	37	hu	hu	PROPN
biomedich-274	148	38	et	et	PROPN
biomedich-274	148	39	al	al	PROPN
biomedich-274	148	40	.	.	PROPN
biomedich-274	148	41	2022	2022	NUM
biomedich-274	148	42	)	)	PUNCT
biomedich-274	148	43	,	,	PUNCT
biomedich-274	148	44	while	while	SCONJ
biomedich-274	148	45	scutellarin	scutellarin	NOUN
biomedich-274	148	46	(	(	PUNCT
biomedich-274	148	47	l4	l4	PROPN
biomedich-274	148	48	)	)	PUNCT
biomedich-274	148	49	gained	gain	VERB
biomedich-274	148	50	from	from	ADP
biomedich-274	148	51	scoparia	scoparia	PROPN
biomedich-274	148	52	dulcis	dulcis	PROPN
biomedich-274	148	53	(	(	PUNCT
biomedich-274	148	54	“	"	PUNCT
biomedich-274	148	55	scutellarin	scutellarin	NOUN
biomedich-274	148	56	|	|	ADV
biomedich-274	148	57	c21h18o12	c21h18o12	PROPN
biomedich-274	148	58	pubchem	pubchem	NOUN
biomedich-274	148	59	”	"	PUNCT
biomedich-274	148	60	n.d	n.d	PROPN
biomedich-274	148	61	.	.	PROPN
biomedich-274	148	62	)	)	PUNCT
biomedich-274	148	63	,	,	PUNCT
biomedich-274	148	64	has	have	AUX
biomedich-274	148	65	been	be	AUX
biomedich-274	148	66	reported	report	VERB
biomedich-274	148	67	as	as	SCONJ
biomedich-274	148	68	to	to	PART
biomedich-274	148	69	be	be	AUX
biomedich-274	148	70	an	an	DET
biomedich-274	148	71	antioxidant	antioxidant	NOUN
biomedich-274	148	72	,	,	PUNCT
biomedich-274	148	73	antitumor	antitumor	PROPN
biomedich-274	148	74	,	,	PUNCT
biomedich-274	148	75	antiplatelet	antiplatelet	NOUN
biomedich-274	148	76	,	,	PUNCT
biomedich-274	148	77	cardioprotective	cardioprotective	ADJ
biomedich-274	148	78	and	and	CCONJ
biomedich-274	148	79	immunomodulatory	immunomodulatory	ADJ
biomedich-274	148	80	(	(	PUNCT
biomedich-274	148	81	wang	wang	PROPN
biomedich-274	148	82	and	and	CCONJ
biomedich-274	148	83	ma	ma	PROPN
biomedich-274	148	84	2018	2018	NUM
biomedich-274	148	85	)	)	PUNCT
biomedich-274	148	86	.	.	PUNCT
biomedich-274	149	1	both	both	PRON
biomedich-274	149	2	have	have	AUX
biomedich-274	149	3	showed	show	VERB
biomedich-274	149	4	an	an	DET
biomedich-274	149	5	excellent	excellent	ADJ
biomedich-274	149	6	affinity	affinity	NOUN
biomedich-274	149	7	for	for	ADP
biomedich-274	149	8	ace2	ace2	NOUN
biomedich-274	149	9	active	active	ADJ
biomedich-274	149	10	residue	residue	NOUN
biomedich-274	149	11	his	his	PRON
biomedich-274	149	12	401	401	NUM
biomedich-274	149	13	,	,	PUNCT
biomedich-274	149	14	with	with	ADP
biomedich-274	149	15	binding	bind	VERB
biomedich-274	149	16	energies	energy	NOUN
biomedich-274	149	17	-8.1	-8.1	ADP
biomedich-274	149	18	and	and	CCONJ
biomedich-274	149	19	8.2	8.2	NUM
biomedich-274	149	20	kcal	kcal	NOUN
biomedich-274	149	21	/	/	SYM
biomedich-274	149	22	mol	mol	NOUN
biomedich-274	149	23	with	with	ADP
biomedich-274	149	24	considerably	considerably	ADV
biomedich-274	149	25	shorter	short	ADJ
biomedich-274	149	26	bond	bond	NOUN
biomedich-274	149	27	lengths	length	NOUN
biomedich-274	149	28	of	of	ADP
biomedich-274	149	29	2.53	2.53	NUM
biomedich-274	149	30	and	and	CCONJ
biomedich-274	149	31	2.50	2.50	NUM
biomedich-274	149	32	angstrom	angstrom	NOUN
biomedich-274	149	33	,	,	PUNCT
biomedich-274	149	34	respectively	respectively	ADV
biomedich-274	149	35	.	.	PUNCT
biomedich-274	150	1	diosmin	diosmin	NOUN
biomedich-274	150	2	(	(	PUNCT
biomedich-274	150	3	l5	l5	PROPN
biomedich-274	150	4	)	)	PUNCT
biomedich-274	150	5	was	be	AUX
biomedich-274	150	6	the	the	DET
biomedich-274	150	7	potential	potential	ADJ
biomedich-274	150	8	drug	drug	NOUN
biomedich-274	150	9	candidate	candidate	NOUN
biomedich-274	150	10	that	that	PRON
biomedich-274	150	11	delivered	deliver	VERB
biomedich-274	150	12	the	the	DET
biomedich-274	150	13	most	most	ADV
biomedich-274	150	14	decent	decent	ADJ
biomedich-274	150	15	results	result	NOUN
biomedich-274	150	16	in	in	ADP
biomedich-274	150	17	terms	term	NOUN
biomedich-274	150	18	of	of	ADP
biomedich-274	150	19	binding	bind	VERB
biomedich-274	150	20	energy	energy	NOUN
biomedich-274	150	21	,	,	PUNCT
biomedich-274	150	22	that	that	PRON
biomedich-274	150	23	was	be	AUX
biomedich-274	150	24	-9.3	-9.3	NOUN
biomedich-274	150	25	kcal	kcal	X
biomedich-274	150	26	/	/	SYM
biomedich-274	150	27	mol	mol	PROPN
biomedich-274	150	28	and	and	CCONJ
biomedich-274	150	29	was	be	AUX
biomedich-274	150	30	bound	bind	VERB
biomedich-274	150	31	to	to	ADP
biomedich-274	150	32	his	his	PRON
biomedich-274	150	33	378	378	NUM
biomedich-274	150	34	and	and	CCONJ
biomedich-274	150	35	his	his	PRON
biomedich-274	150	36	401	401	NUM
biomedich-274	150	37	.	.	PUNCT
biomedich-274	151	1	it	it	PRON
biomedich-274	151	2	has	have	AUX
biomedich-274	151	3	been	be	AUX
biomedich-274	151	4	reported	report	VERB
biomedich-274	151	5	that	that	SCONJ
biomedich-274	151	6	diosmin	diosmin	NOUN
biomedich-274	151	7	(	(	PUNCT
biomedich-274	151	8	l5	l5	PROPN
biomedich-274	151	9	)	)	PUNCT
biomedich-274	151	10	,	,	PUNCT
biomedich-274	151	11	obtained	obtain	VERB
biomedich-274	151	12	from	from	ADP
biomedich-274	151	13	asyneuma	asyneuma	NOUN
biomedich-274	151	14	argutum	argutum	NOUN
biomedich-274	151	15	(	(	PUNCT
biomedich-274	151	16	“	"	PUNCT
biomedich-274	151	17	diosmin	diosmin	NOUN
biomedich-274	151	18	|	|	ADV
biomedich-274	151	19	c28h32o15	c28h32o15	PROPN
biomedich-274	151	20	pubchem	pubchem	NOUN
biomedich-274	151	21	”	"	PUNCT
biomedich-274	151	22	n.d	n.d	PROPN
biomedich-274	151	23	.	.	PROPN
biomedich-274	151	24	)	)	PUNCT
biomedich-274	151	25	,	,	PUNCT
biomedich-274	151	26	works	work	VERB
biomedich-274	151	27	as	as	ADP
biomedich-274	151	28	an	an	DET
biomedich-274	151	29	antioxidant	antioxidant	NOUN
biomedich-274	151	30	as	as	ADV
biomedich-274	151	31	well	well	ADV
biomedich-274	151	32	as	as	ADP
biomedich-274	151	33	relieves	relieve	VERB
biomedich-274	151	34	venous	venous	ADJ
biomedich-274	151	35	insufficiencies	insufficiency	NOUN
biomedich-274	151	36	(	(	PUNCT
biomedich-274	151	37	feldo	feldo	PROPN
biomedich-274	151	38	et	et	PROPN
biomedich-274	151	39	al	al	PROPN
biomedich-274	151	40	.	.	PROPN
biomedich-274	151	41	2018	2018	NUM
biomedich-274	151	42	)	)	PUNCT
biomedich-274	151	43	.	.	PUNCT
biomedich-274	152	1	some	some	DET
biomedich-274	152	2	studies	study	NOUN
biomedich-274	152	3	have	have	AUX
biomedich-274	152	4	revealed	reveal	VERB
biomedich-274	152	5	that	that	SCONJ
biomedich-274	152	6	apigenin	apigenin	ADJ
biomedich-274	152	7	7	7	NUM
biomedich-274	152	8	-	-	PUNCT
biomedich-274	152	9	o	o	NOUN
biomedich-274	152	10	-	-	NOUN
biomedich-274	152	11	glucoside	glucoside	NOUN
biomedich-274	152	12	(	(	PUNCT
biomedich-274	152	13	l6	l6	PROPN
biomedich-274	152	14	)	)	PUNCT
biomedich-274	152	15	from	from	ADP
biomedich-274	152	16	plant	plant	NOUN
biomedich-274	152	17	lonicera	lonicera	NOUN
biomedich-274	152	18	japonica	japonica	NOUN
biomedich-274	152	19	(	(	PUNCT
biomedich-274	152	20	“	"	PUNCT
biomedich-274	152	21	apigenin	apigenin	ADJ
biomedich-274	152	22	7	7	NUM
biomedich-274	152	23	-	-	PUNCT
biomedich-274	152	24	o	o	NOUN
biomedich-274	152	25	-	-	ADJ
biomedich-274	152	26	beta	beta	NOUN
biomedich-274	152	27	-	-	PUNCT
biomedich-274	152	28	dglucoside	dglucoside	NOUN
biomedich-274	152	29	|	|	ADV
biomedich-274	152	30	c21h20o10	c21h20o10	VERB
biomedich-274	152	31	pubchem	pubchem	NOUN
biomedich-274	152	32	”	"	PUNCT
biomedich-274	152	33	n.d	n.d	PROPN
biomedich-274	152	34	.	.	PROPN
biomedich-274	152	35	)	)	PUNCT
biomedich-274	152	36	,	,	PUNCT
biomedich-274	152	37	was	be	AUX
biomedich-274	152	38	found	find	VERB
biomedich-274	152	39	to	to	PART
biomedich-274	152	40	be	be	AUX
biomedich-274	152	41	antimicrobial	antimicrobial	ADJ
biomedich-274	152	42	and	and	CCONJ
biomedich-274	152	43	cytotoxic	cytotoxic	ADJ
biomedich-274	152	44	(	(	PUNCT
biomedich-274	152	45	nie	nie	PROPN
biomedich-274	152	46	et	et	PROPN
biomedich-274	152	47	al	al	PROPN
biomedich-274	152	48	.	.	PROPN
biomedich-274	152	49	2018	2018	NUM
biomedich-274	152	50	)	)	PUNCT
biomedich-274	152	51	and	and	CCONJ
biomedich-274	152	52	this	this	DET
biomedich-274	152	53	study	study	NOUN
biomedich-274	152	54	has	have	AUX
biomedich-274	152	55	detected	detect	VERB
biomedich-274	152	56	l6	l6	PROPN
biomedich-274	152	57	as	as	ADP
biomedich-274	152	58	a	a	DET
biomedich-274	152	59	potential	potential	ADJ
biomedich-274	152	60	inhibitor	inhibitor	NOUN
biomedich-274	152	61	of	of	ADP
biomedich-274	152	62	ace2	ace2	NOUN
biomedich-274	152	63	with	with	ADP
biomedich-274	152	64	a	a	DET
biomedich-274	152	65	binding	bind	VERB
biomedich-274	152	66	energy	energy	NOUN
biomedich-274	152	67	of	of	ADP
biomedich-274	152	68	-7.9	-7.9	ADJ
biomedich-274	152	69	kcal	kcal	NOUN
biomedich-274	152	70	/	/	SYM
biomedich-274	152	71	mol	mol	NOUN
biomedich-274	152	72	with	with	ADP
biomedich-274	152	73	active	active	ADJ
biomedich-274	152	74	residues	residue	NOUN
biomedich-274	152	75	and	and	CCONJ
biomedich-274	152	76	shorter	short	ADJ
biomedich-274	152	77	bond	bond	NOUN
biomedich-274	152	78	lengths	length	NOUN
biomedich-274	152	79	.	.	PUNCT
biomedich-274	153	1	isoorientin	isoorientin	ADJ
biomedich-274	153	2	(	(	PUNCT
biomedich-274	153	3	l7	l7	PROPN
biomedich-274	153	4	)	)	PUNCT
biomedich-274	153	5	,	,	PUNCT
biomedich-274	153	6	derived	derive	VERB
biomedich-274	153	7	from	from	ADP
biomedich-274	153	8	carex	carex	PROPN
biomedich-274	153	9	fraseriana	fraseriana	PROPN
biomedich-274	153	10	(	(	PUNCT
biomedich-274	153	11	“	"	PUNCT
biomedich-274	153	12	isoorientin	isoorientin	ADJ
biomedich-274	153	13	|	|	CCONJ
biomedich-274	153	14	c21h20o11	c21h20o11	PROPN
biomedich-274	153	15	pubchem	pubchem	NOUN
biomedich-274	153	16	”	"	PUNCT
biomedich-274	153	17	n.d	n.d	PROPN
biomedich-274	153	18	.	.	PROPN
biomedich-274	153	19	)	)	PUNCT
biomedich-274	153	20	,	,	PUNCT
biomedich-274	153	21	bound	bind	VERB
biomedich-274	153	22	to	to	ADP
biomedich-274	153	23	the	the	DET
biomedich-274	153	24	target	target	NOUN
biomedich-274	153	25	with	with	ADP
biomedich-274	153	26	energies	energy	NOUN
biomedich-274	153	27	of	of	ADP
biomedich-274	153	28	-7.4	-7.4	X
biomedich-274	153	29	kcal	kcal	PROPN
biomedich-274	153	30	/	/	SYM
biomedich-274	153	31	mol	mol	PROPN
biomedich-274	153	32	and	and	CCONJ
biomedich-274	153	33	showed	show	VERB
biomedich-274	153	34	potent	potent	ADJ
biomedich-274	153	35	affinity	affinity	NOUN
biomedich-274	153	36	for	for	ADP
biomedich-274	153	37	active	active	ADJ
biomedich-274	153	38	site	site	NOUN
biomedich-274	153	39	.	.	PUNCT
biomedich-274	154	1	a	a	DET
biomedich-274	154	2	study	study	NOUN
biomedich-274	154	3	has	have	AUX
biomedich-274	154	4	outlined	outline	VERB
biomedich-274	154	5	the	the	DET
biomedich-274	154	6	role	role	NOUN
biomedich-274	154	7	of	of	ADP
biomedich-274	154	8	isoorientin	isoorientin	ADJ
biomedich-274	154	9	(	(	PUNCT
biomedich-274	154	10	l7	l7	PROPN
biomedich-274	154	11	)	)	PUNCT
biomedich-274	154	12	in	in	ADP
biomedich-274	154	13	lowering	lower	VERB
biomedich-274	154	14	inflammatory	inflammatory	ADJ
biomedich-274	154	15	mediators	mediator	NOUN
biomedich-274	154	16	,	,	PUNCT
biomedich-274	154	17	relieving	relieve	VERB
biomedich-274	154	18	algesia	algesia	PROPN
biomedich-274	154	19	and	and	CCONJ
biomedich-274	154	20	combating	combat	VERB
biomedich-274	154	21	free	free	ADJ
biomedich-274	154	22	radicals	radical	NOUN
biomedich-274	154	23	as	as	ADV
biomedich-274	154	24	well	well	ADV
biomedich-274	154	25	(	(	PUNCT
biomedich-274	154	26	yuan	yuan	NOUN
biomedich-274	154	27	et	et	PROPN
biomedich-274	154	28	al	al	PROPN
biomedich-274	154	29	.	.	PROPN
biomedich-274	154	30	2016	2016	NUM
biomedich-274	154	31	)	)	PUNCT
biomedich-274	154	32	.	.	PUNCT
biomedich-274	155	1	lonicerin	lonicerin	NOUN
biomedich-274	155	2	(	(	PUNCT
biomedich-274	155	3	l8	l8	PROPN
biomedich-274	155	4	)	)	PUNCT
biomedich-274	155	5	,	,	PUNCT
biomedich-274	155	6	a	a	DET
biomedich-274	155	7	chemical	chemical	NOUN
biomedich-274	155	8	constituent	constituent	NOUN
biomedich-274	155	9	of	of	ADP
biomedich-274	155	10	lonicera	lonicera	NOUN
biomedich-274	155	11	japonica	japonica	PROPN
biomedich-274	155	12	(	(	PUNCT
biomedich-274	155	13	“	"	PUNCT
biomedich-274	155	14	lonicerin	lonicerin	NOUN
biomedich-274	155	15	|	|	ADV
biomedich-274	155	16	c27h30o15	c27h30o15	PROPN
biomedich-274	155	17	pubchem	pubchem	NOUN
biomedich-274	155	18	”	"	PUNCT
biomedich-274	155	19	n.d	n.d	PROPN
biomedich-274	155	20	.	.	PROPN
biomedich-274	155	21	)	)	PUNCT
biomedich-274	155	22	,	,	PUNCT
biomedich-274	155	23	has	have	AUX
biomedich-274	155	24	also	also	ADV
biomedich-274	155	25	been	be	AUX
biomedich-274	155	26	described	describe	VERB
biomedich-274	155	27	for	for	ADP
biomedich-274	155	28	its	its	PRON
biomedich-274	155	29	potent	potent	ADJ
biomedich-274	155	30	antipseudomonal	antipseudomonal	ADJ
biomedich-274	155	31	pharmacology	pharmacology	NOUN
biomedich-274	155	32	(	(	PUNCT
biomedich-274	155	33	xu	xu	INTJ
biomedich-274	155	34	et	et	PROPN
biomedich-274	155	35	al	al	PROPN
biomedich-274	155	36	.	.	PROPN
biomedich-274	155	37	2019	2019	NUM
biomedich-274	155	38	)	)	PUNCT
biomedich-274	155	39	.	.	PUNCT
biomedich-274	156	1	in	in	ADP
biomedich-274	156	2	this	this	DET
biomedich-274	156	3	study	study	NOUN
biomedich-274	156	4	,	,	PUNCT
biomedich-274	156	5	the	the	DET
biomedich-274	156	6	binding	bind	VERB
biomedich-274	156	7	energy	energy	NOUN
biomedich-274	156	8	of	of	ADP
biomedich-274	156	9	-8.4	-8.4	X
biomedich-274	156	10	kcal	kcal	NOUN
biomedich-274	156	11	/	/	SYM
biomedich-274	156	12	mol	mol	NOUN
biomedich-274	156	13	of	of	ADP
biomedich-274	156	14	lonicerin	lonicerin	NOUN
biomedich-274	156	15	(	(	PUNCT
biomedich-274	156	16	l8	l8	PROPN
biomedich-274	156	17	)	)	PUNCT
biomedich-274	156	18	and	and	CCONJ
biomedich-274	156	19	its	its	PRON
biomedich-274	156	20	connection	connection	NOUN
biomedich-274	156	21	with	with	ADP
biomedich-274	156	22	his	his	PRON
biomedich-274	156	23	378	378	NUM
biomedich-274	156	24	and	and	CCONJ
biomedich-274	156	25	glu	glu	VERB
biomedich-274	156	26	402	402	NUM
biomedich-274	156	27	tells	tell	VERB
biomedich-274	156	28	the	the	DET
biomedich-274	156	29	possible	possible	ADJ
biomedich-274	156	30	inhibitory	inhibitory	ADJ
biomedich-274	156	31	activity	activity	NOUN
biomedich-274	156	32	for	for	ADP
biomedich-274	156	33	ace2	ace2	NOUN
biomedich-274	156	34	.	.	PUNCT
biomedich-274	157	1	tricin	tricin	VERB
biomedich-274	157	2	7	7	NUM
biomedich-274	157	3	-	-	PUNCT
biomedich-274	157	4	o	o	NOUN
biomedich-274	157	5	-	-	NOUN
biomedich-274	157	6	glucouronide	glucouronide	ADJ
biomedich-274	157	7	(	(	PUNCT
biomedich-274	157	8	l9	l9	PROPN
biomedich-274	157	9	)	)	PUNCT
biomedich-274	157	10	,	,	PUNCT
biomedich-274	157	11	isolated	isolate	VERB
biomedich-274	157	12	from	from	ADP
biomedich-274	157	13	scutellaria	scutellaria	NOUN
biomedich-274	157	14	discolor	discolor	NOUN
biomedich-274	157	15	(	(	PUNCT
biomedich-274	157	16	“	"	PUNCT
biomedich-274	157	17	tricin	tricin	VERB
biomedich-274	157	18	7	7	NUM
biomedich-274	157	19	-	-	PUNCT
biomedich-274	157	20	o	o	NOUN
biomedich-274	157	21	-	-	ADJ
biomedich-274	157	22	glucuronide	glucuronide	ADJ
biomedich-274	157	23	|	|	CCONJ
biomedich-274	157	24	c23h22o13	c23h22o13	PROPN
biomedich-274	157	25	pubchem	pubchem	PROPN
biomedich-274	157	26	”	"	PUNCT
biomedich-274	157	27	n.d	n.d	PROPN
biomedich-274	157	28	.	.	PROPN
biomedich-274	157	29	)	)	PUNCT
biomedich-274	157	30	,	,	PUNCT
biomedich-274	157	31	is	be	AUX
biomedich-274	157	32	known	know	VERB
biomedich-274	157	33	for	for	ADP
biomedich-274	157	34	its	its	PRON
biomedich-274	157	35	inhibition	inhibition	NOUN
biomedich-274	157	36	for	for	ADP
biomedich-274	157	37	cervical	cervical	ADJ
biomedich-274	157	38	cancer	cancer	NOUN
biomedich-274	157	39	cell	cell	NOUN
biomedich-274	157	40	growth	growth	NOUN
biomedich-274	157	41	through	through	ADP
biomedich-274	157	42	upheld	upheld	NOUN
biomedich-274	157	43	expression	expression	NOUN
biomedich-274	157	44	of	of	ADP
biomedich-274	157	45	bax	bax	PROPN
biomedich-274	157	46	and	and	CCONJ
biomedich-274	157	47	caspases	caspases	PROPN
biomedich-274	157	48	(	(	PUNCT
biomedich-274	157	49	laishram	laishram	PROPN
biomedich-274	157	50	et	et	PROPN
biomedich-274	157	51	al	al	PROPN
biomedich-274	157	52	.	.	PROPN
biomedich-274	157	53	2015	2015	NUM
biomedich-274	157	54	)	)	PUNCT
biomedich-274	157	55	,	,	PUNCT
biomedich-274	157	56	seems	seem	VERB
biomedich-274	157	57	to	to	PART
biomedich-274	157	58	have	have	VERB
biomedich-274	157	59	a	a	DET
biomedich-274	157	60	significant	significant	ADJ
biomedich-274	157	61	potential	potential	NOUN
biomedich-274	157	62	to	to	PART
biomedich-274	157	63	bind	bind	VERB
biomedich-274	157	64	ace2	ace2	NOUN
biomedich-274	157	65	in	in	ADP
biomedich-274	157	66	human	human	NOUN
biomedich-274	157	67	,	,	PUNCT
biomedich-274	157	68	as	as	ADP
biomedich-274	157	69	per	per	ADP
biomedich-274	157	70	this	this	DET
biomedich-274	157	71	study	study	NOUN
biomedich-274	157	72	,	,	PUNCT
biomedich-274	157	73	with	with	ADP
biomedich-274	157	74	optimistic	optimistic	ADJ
biomedich-274	157	75	energy	energy	NOUN
biomedich-274	157	76	of	of	ADP
biomedich-274	157	77	-8.0	-8.0	INTJ
biomedich-274	157	78	kcal	kcal	PROPN
biomedich-274	157	79	/	/	SYM
biomedich-274	157	80	mol	mol	PROPN
biomedich-274	157	81	,	,	PUNCT
biomedich-274	157	82	with	with	ADP
biomedich-274	157	83	bond	bond	NOUN
biomedich-274	157	84	length	length	NOUN
biomedich-274	157	85	of	of	ADP
biomedich-274	157	86	2.11	2.11	NUM
biomedich-274	157	87	angstrom	angstrom	NOUN
biomedich-274	157	88	with	with	ADP
biomedich-274	157	89	glu	glu	PROPN
biomedich-274	157	90	401	401	NUM
biomedich-274	157	91	.	.	PUNCT
biomedich-274	158	1	swertisin	swertisin	PROPN
biomedich-274	158	2	(	(	PUNCT
biomedich-274	158	3	l10	l10	PROPN
biomedich-274	158	4	)	)	PUNCT
biomedich-274	158	5	,	,	PUNCT
biomedich-274	158	6	a	a	DET
biomedich-274	158	7	priniciple	priniciple	NOUN
biomedich-274	158	8	component	component	NOUN
biomedich-274	158	9	of	of	ADP
biomedich-274	158	10	gentiana	gentiana	PROPN
biomedich-274	158	11	orbicularis	orbicularis	PROPN
biomedich-274	158	12	(	(	PUNCT
biomedich-274	158	13	“	"	PUNCT
biomedich-274	158	14	swertisin	swertisin	VERB
biomedich-274	158	15	|	|	ADV
biomedich-274	158	16	c22h22o10	c22h22o10	NOUN
biomedich-274	158	17	pubchem	pubchem	NOUN
biomedich-274	158	18	”	"	PUNCT
biomedich-274	158	19	n.d	n.d	PROPN
biomedich-274	158	20	.	.	PROPN
biomedich-274	158	21	)	)	PUNCT
biomedich-274	158	22	,	,	PUNCT
biomedich-274	158	23	well	well	INTJ
biomedich-274	158	24	known	know	VERB
biomedich-274	158	25	for	for	ADP
biomedich-274	158	26	its	its	PRON
biomedich-274	158	27	antioxidant	antioxidant	ADJ
biomedich-274	158	28	and	and	CCONJ
biomedich-274	158	29	inflammation	inflammation	NOUN
biomedich-274	158	30	fighting	fight	VERB
biomedich-274	158	31	tendencies	tendency	NOUN
biomedich-274	158	32	(	(	PUNCT
biomedich-274	158	33	“	"	PUNCT
biomedich-274	158	34	swertisin	swertisin	NOUN
biomedich-274	158	35	(	(	PUNCT
biomedich-274	158	36	chebi:131838	chebi:131838	NOUN
biomedich-274	158	37	)	)	PUNCT
biomedich-274	158	38	”	"	PUNCT
biomedich-274	158	39	n.d	n.d	PROPN
biomedich-274	158	40	.	.	PROPN
biomedich-274	158	41	)	)	PUNCT
biomedich-274	158	42	,	,	PUNCT
biomedich-274	158	43	came	come	VERB
biomedich-274	158	44	up	up	ADP
biomedich-274	158	45	with	with	ADP
biomedich-274	158	46	a	a	DET
biomedich-274	158	47	binding	bind	VERB
biomedich-274	158	48	energy	energy	NOUN
biomedich-274	158	49	value	value	NOUN
biomedich-274	158	50	of	of	ADP
biomedich-274	158	51	-7.3	-7.3	PROPN
biomedich-274	158	52	kcal	kcal	NOUN
biomedich-274	158	53	/	/	SYM
biomedich-274	158	54	mol	mol	NOUN
biomedich-274	158	55	and	and	CCONJ
biomedich-274	158	56	interactions	interaction	NOUN
biomedich-274	158	57	with	with	ADP
biomedich-274	158	58	his	his	PRON
biomedich-274	158	59	378	378	NUM
biomedich-274	158	60	and	and	CCONJ
biomedich-274	158	61	his	his	PRON
biomedich-274	158	62	401	401	NUM
biomedich-274	158	63	.	.	PUNCT
biomedich-274	159	1	hence	hence	ADV
biomedich-274	159	2	,	,	PUNCT
biomedich-274	159	3	all	all	DET
biomedich-274	159	4	the	the	DET
biomedich-274	159	5	potential	potential	ADJ
biomedich-274	159	6	drug	drug	NOUN
biomedich-274	159	7	candidates	candidate	NOUN
biomedich-274	159	8	have	have	AUX
biomedich-274	159	9	furnished	furnish	VERB
biomedich-274	159	10	hopeful	hopeful	ADJ
biomedich-274	159	11	results	result	NOUN
biomedich-274	159	12	in	in	ADP
biomedich-274	159	13	terms	term	NOUN
biomedich-274	159	14	of	of	ADP
biomedich-274	159	15	potential	potential	ADJ
biomedich-274	159	16	inhibition	inhibition	NOUN
biomedich-274	159	17	of	of	ADP
biomedich-274	159	18	ace2	ace2	NOUN
biomedich-274	159	19	in	in	ADP
biomedich-274	159	20	human	human	NOUN
biomedich-274	159	21	that	that	PRON
biomedich-274	159	22	can	can	AUX
biomedich-274	159	23	be	be	AUX
biomedich-274	159	24	further	far	ADV
biomedich-274	159	25	studied	study	VERB
biomedich-274	159	26	and	and	CCONJ
biomedich-274	159	27	validated	validate	VERB
biomedich-274	159	28	through	through	ADP
biomedich-274	159	29	in	in	ADV
biomedich-274	159	30	-	-	PUNCT
biomedich-274	159	31	vitro	vitro	X
biomedich-274	159	32	and	and	CCONJ
biomedich-274	159	33	in	in	ADP
biomedich-274	159	34	-	-	PUNCT
biomedich-274	159	35	vivo	vivo	NOUN
biomedich-274	159	36	studies	study	NOUN
biomedich-274	159	37	.	.	PUNCT
biomedich-274	160	1	the	the	DET
biomedich-274	160	2	molecular	molecular	ADJ
biomedich-274	160	3	dynamics	dynamic	NOUN
biomedich-274	160	4	simulation	simulation	NOUN
biomedich-274	160	5	study	study	NOUN
biomedich-274	160	6	clues	clue	VERB
biomedich-274	160	7	that	that	SCONJ
biomedich-274	160	8	the	the	DET
biomedich-274	160	9	studied	studied	ADJ
biomedich-274	160	10	complex	complex	NOUN
biomedich-274	160	11	had	have	VERB
biomedich-274	160	12	a	a	DET
biomedich-274	160	13	substantial	substantial	ADJ
biomedich-274	160	14	degree	degree	NOUN
biomedich-274	160	15	of	of	ADP
biomedich-274	160	16	deformability	deformability	NOUN
biomedich-274	160	17	.	.	PUNCT
biomedich-274	161	1	the	the	DET
biomedich-274	161	2	low	low	ADJ
biomedich-274	161	3	eigenvalue	eigenvalue	NOUN
biomedich-274	161	4	,	,	PUNCT
biomedich-274	161	5	the	the	DET
biomedich-274	161	6	covariance	covariance	NOUN
biomedich-274	161	7	map	map	NOUN
biomedich-274	161	8	and	and	CCONJ
biomedich-274	161	9	the	the	DET
biomedich-274	161	10	elastic	elastic	ADJ
biomedich-274	161	11	network	network	NOUN
biomedich-274	161	12	of	of	ADP
biomedich-274	161	13	the	the	DET
biomedich-274	161	14	studied	study	VERB
biomedich-274	161	15	complex	complex	NOUN
biomedich-274	161	16	are	be	AUX
biomedich-274	161	17	the	the	DET
biomedich-274	161	18	evidences	evidence	NOUN
biomedich-274	161	19	of	of	ADP
biomedich-274	161	20	the	the	DET
biomedich-274	161	21	promising	promising	ADJ
biomedich-274	161	22	deformability	deformability	NOUN
biomedich-274	161	23	and	and	CCONJ
biomedich-274	161	24	admissible	admissible	ADJ
biomedich-274	161	25	dynamics	dynamic	NOUN
biomedich-274	161	26	of	of	ADP
biomedich-274	161	27	the	the	DET
biomedich-274	161	28	molecule	molecule	NOUN
biomedich-274	161	29	.	.	PUNCT
biomedich-274	162	1	conclusion	conclusion	NOUN
biomedich-274	162	2	in	in	ADP
biomedich-274	162	3	this	this	DET
biomedich-274	162	4	study	study	NOUN
biomedich-274	162	5	,	,	PUNCT
biomedich-274	162	6	it	it	PRON
biomedich-274	162	7	is	be	AUX
biomedich-274	162	8	concluded	conclude	VERB
biomedich-274	162	9	that	that	SCONJ
biomedich-274	162	10	the	the	DET
biomedich-274	162	11	ligands	ligand	NOUN
biomedich-274	162	12	l1l10	l1l10	NOUN
biomedich-274	162	13	have	have	AUX
biomedich-274	162	14	shown	show	VERB
biomedich-274	162	15	a	a	DET
biomedich-274	162	16	potent	potent	ADJ
biomedich-274	162	17	activity	activity	NOUN
biomedich-274	162	18	for	for	ADP
biomedich-274	162	19	ace2	ace2	NOUN
biomedich-274	162	20	protein	protein	NOUN
biomedich-274	162	21	receptor	receptor	NOUN
biomedich-274	162	22	for	for	ADP
biomedich-274	162	23	potentially	potentially	ADV
biomedich-274	162	24	averting	avert	VERB
biomedich-274	162	25	the	the	DET
biomedich-274	162	26	entry	entry	NOUN
biomedich-274	162	27	of	of	ADP
biomedich-274	162	28	sarscov-2	sarscov-2	NUM
biomedich-274	162	29	into	into	ADP
biomedich-274	162	30	the	the	DET
biomedich-274	162	31	cells	cell	NOUN
biomedich-274	162	32	.	.	PUNCT
biomedich-274	163	1	the	the	DET
biomedich-274	163	2	ligands	ligand	NOUN
biomedich-274	163	3	have	have	AUX
biomedich-274	163	4	manifested	manifest	VERB
biomedich-274	163	5	pertinent	pertinent	ADJ
biomedich-274	163	6	interactions	interaction	NOUN
biomedich-274	163	7	with	with	ADP
biomedich-274	163	8	ace2	ace2	NOUN
biomedich-274	163	9	active	active	ADJ
biomedich-274	163	10	residues	residue	NOUN
biomedich-274	163	11	,	,	PUNCT
biomedich-274	163	12	showing	show	VERB
biomedich-274	163	13	highly	highly	ADV
biomedich-274	163	14	encouraging	encouraging	ADJ
biomedich-274	163	15	binding	bind	VERB
biomedich-274	163	16	energies	energy	NOUN
biomedich-274	163	17	.	.	PUNCT
biomedich-274	164	1	the	the	DET
biomedich-274	164	2	molecular	molecular	ADJ
biomedich-274	164	3	dynamics	dynamic	NOUN
biomedich-274	164	4	simulation	simulation	NOUN
biomedich-274	164	5	studies	study	NOUN
biomedich-274	164	6	also	also	ADV
biomedich-274	164	7	provided	provide	VERB
biomedich-274	164	8	hopeful	hopeful	ADJ
biomedich-274	164	9	results	result	NOUN
biomedich-274	164	10	.	.	PUNCT
biomedich-274	165	1	however	however	ADV
biomedich-274	165	2	,	,	PUNCT
biomedich-274	165	3	in	in	ADV
biomedich-274	165	4	-	-	PUNCT
biomedich-274	165	5	vitro	vitro	X
biomedich-274	165	6	and	and	CCONJ
biomedich-274	165	7	in	in	ADP
biomedich-274	165	8	-	-	PUNCT
biomedich-274	165	9	vivo	vivo	NOUN
biomedich-274	165	10	studies	study	NOUN
biomedich-274	165	11	are	be	AUX
biomedich-274	165	12	required	require	VERB
biomedich-274	165	13	to	to	PART
biomedich-274	165	14	confirm	confirm	VERB
biomedich-274	165	15	these	these	DET
biomedich-274	165	16	findings	finding	NOUN
biomedich-274	165	17	.	.	PUNCT
biomedich-274	166	1	furthermore	furthermore	ADV
biomedich-274	166	2	,	,	PUNCT
biomedich-274	166	3	pharmaceutical	pharmaceutical	ADJ
biomedich-274	166	4	studies	study	NOUN
biomedich-274	166	5	are	be	AUX
biomedich-274	166	6	also	also	ADV
biomedich-274	166	7	recommended	recommend	VERB
biomedich-274	166	8	for	for	ADP
biomedich-274	166	9	these	these	DET
biomedich-274	166	10	compounds	compound	NOUN
biomedich-274	166	11	in	in	ADP
biomedich-274	166	12	formulating	formulate	VERB
biomedich-274	166	13	them	they	PRON
biomedich-274	166	14	as	as	ADP
biomedich-274	166	15	a	a	DET
biomedich-274	166	16	suitable	suitable	ADJ
biomedich-274	166	17	drug	drug	NOUN
biomedich-274	166	18	delivery	delivery	NOUN
biomedich-274	166	19	system	system	NOUN
biomedich-274	166	20	for	for	ADP
biomedich-274	166	21	maximal	maximal	ADJ
biomedich-274	166	22	therapeutic	therapeutic	ADJ
biomedich-274	166	23	efficacy	efficacy	NOUN
biomedich-274	166	24	.	.	PUNCT
biomedich-274	167	1	covid-19	covid-19	PROPN
biomedich-274	167	2	had	have	AUX
biomedich-274	167	3	been	be	AUX
biomedich-274	167	4	very	very	ADV
biomedich-274	167	5	grim	grim	ADJ
biomedich-274	167	6	challenge	challenge	NOUN
biomedich-274	167	7	for	for	ADP
biomedich-274	167	8	the	the	DET
biomedich-274	167	9	health	health	NOUN
biomedich-274	167	10	system	system	NOUN
biomedich-274	167	11	around	around	ADP
biomedich-274	167	12	the	the	DET
biomedich-274	167	13	globe	globe	NOUN
biomedich-274	167	14	.	.	PUNCT
biomedich-274	168	1	the	the	DET
biomedich-274	168	2	focus	focus	NOUN
biomedich-274	168	3	of	of	ADP
biomedich-274	168	4	the	the	DET
biomedich-274	168	5	ongoing	ongoing	ADJ
biomedich-274	168	6	research	research	NOUN
biomedich-274	168	7	in	in	ADP
biomedich-274	168	8	the	the	DET
biomedich-274	168	9	field	field	NOUN
biomedich-274	168	10	of	of	ADP
biomedich-274	168	11	drug	drug	NOUN
biomedich-274	168	12	discovery	discovery	NOUN
biomedich-274	168	13	revolves	revolve	VERB
biomedich-274	168	14	around	around	ADP
biomedich-274	168	15	the	the	DET
biomedich-274	168	16	drug	drug	NOUN
biomedich-274	168	17	development	development	NOUN
biomedich-274	168	18	for	for	ADP
biomedich-274	168	19	covid-19	covid-19	PROPN
biomedich-274	168	20	.	.	PUNCT
biomedich-274	169	1	many	many	ADJ
biomedich-274	169	2	concerns	concern	NOUN
biomedich-274	169	3	have	have	AUX
biomedich-274	169	4	developed	develop	VERB
biomedich-274	169	5	in	in	ADP
biomedich-274	169	6	terms	term	NOUN
biomedich-274	169	7	of	of	ADP
biomedich-274	169	8	efficacy	efficacy	NOUN
biomedich-274	169	9	as	as	ADV
biomedich-274	169	10	well	well	ADV
biomedich-274	169	11	as	as	ADP
biomedich-274	169	12	safety	safety	NOUN
biomedich-274	169	13	for	for	ADP
biomedich-274	169	14	many	many	ADJ
biomedich-274	169	15	drugs	drug	NOUN
biomedich-274	169	16	to	to	PART
biomedich-274	169	17	be	be	AUX
biomedich-274	169	18	used	use	VERB
biomedich-274	169	19	against	against	ADP
biomedich-274	169	20	this	this	DET
biomedich-274	169	21	virus	virus	NOUN
biomedich-274	169	22	.	.	PUNCT
biomedich-274	170	1	on	on	ADP
biomedich-274	170	2	ibrahim	ibrahim	PROPN
biomedich-274	170	3	&	&	CCONJ
biomedich-274	170	4	ul	ul	PROPN
biomedich-274	170	5	haq	haq	PROPN
biomedich-274	170	6	–	–	PUNCT
biomedich-274	170	7	flavone	flavone	NOUN
biomedich-274	170	8	glycosides	glycoside	NOUN
biomedich-274	170	9	attenuate	attenuate	VERB
biomedich-274	170	10	covid-19	covid-19	PROPN
biomedich-274	170	11	107	107	NUM
biomedich-274	170	12	the	the	DET
biomedich-274	170	13	basis	basis	NOUN
biomedich-274	170	14	of	of	ADP
biomedich-274	170	15	findings	finding	NOUN
biomedich-274	170	16	of	of	ADP
biomedich-274	170	17	this	this	DET
biomedich-274	170	18	study	study	NOUN
biomedich-274	170	19	,	,	PUNCT
biomedich-274	170	20	an	an	DET
biomedich-274	170	21	inference	inference	NOUN
biomedich-274	170	22	could	could	AUX
biomedich-274	170	23	be	be	AUX
biomedich-274	170	24	drawn	draw	VERB
biomedich-274	170	25	that	that	SCONJ
biomedich-274	170	26	these	these	DET
biomedich-274	170	27	flavone	flavone	NOUN
biomedich-274	170	28	glycosides	glycoside	NOUN
biomedich-274	170	29	could	could	AUX
biomedich-274	170	30	be	be	AUX
biomedich-274	170	31	utilized	utilize	VERB
biomedich-274	170	32	as	as	ADP
biomedich-274	170	33	potential	potential	ADJ
biomedich-274	170	34	drug	drug	NOUN
biomedich-274	170	35	molecules	molecule	NOUN
biomedich-274	170	36	for	for	ADP
biomedich-274	170	37	restricting	restrict	VERB
biomedich-274	170	38	the	the	DET
biomedich-274	170	39	entry	entry	NOUN
biomedich-274	170	40	of	of	ADP
biomedich-274	170	41	sarscov-2	sarscov-2	NUM
biomedich-274	170	42	entry	entry	NOUN
biomedich-274	170	43	into	into	ADP
biomedich-274	170	44	the	the	DET
biomedich-274	170	45	cells	cell	NOUN
biomedich-274	170	46	they	they	PRON
biomedich-274	170	47	infect	infect	VERB
biomedich-274	170	48	by	by	ADP
biomedich-274	170	49	blocking	block	VERB
biomedich-274	170	50	ace2	ace2	NOUN
biomedich-274	170	51	receptor	receptor	NOUN
biomedich-274	170	52	protein	protein	NOUN
biomedich-274	170	53	,	,	PUNCT
biomedich-274	170	54	especially	especially	ADV
biomedich-274	170	55	in	in	ADP
biomedich-274	170	56	lungs	lung	NOUN
biomedich-274	170	57	.	.	PUNCT
biomedich-274	171	1	this	this	DET
biomedich-274	171	2	study	study	NOUN
biomedich-274	171	3	will	will	AUX
biomedich-274	171	4	assist	assist	VERB
biomedich-274	171	5	the	the	DET
biomedich-274	171	6	researchers	researcher	NOUN
biomedich-274	171	7	for	for	ADP
biomedich-274	171	8	preclinical	preclinical	ADJ
biomedich-274	171	9	and	and	CCONJ
biomedich-274	171	10	clinical	clinical	ADJ
biomedich-274	171	11	investigation	investigation	NOUN
biomedich-274	171	12	of	of	ADP
biomedich-274	171	13	these	these	DET
biomedich-274	171	14	potential	potential	ADJ
biomedich-274	171	15	drug	drug	NOUN
biomedich-274	171	16	molecules	molecule	NOUN
biomedich-274	171	17	.	.	PUNCT
biomedich-274	172	1	acknowledgement	acknowledgement	NOUN
biomedich-274	172	2	:	:	PUNCT
biomedich-274	172	3	the	the	DET
biomedich-274	172	4	study	study	NOUN
biomedich-274	172	5	is	be	AUX
biomedich-274	172	6	carried	carry	VERB
biomedich-274	172	7	out	out	ADP
biomedich-274	172	8	entirely	entirely	ADV
biomedich-274	172	9	by	by	ADP
biomedich-274	172	10	the	the	DET
biomedich-274	172	11	authors	author	NOUN
biomedich-274	172	12	,	,	PUNCT
biomedich-274	172	13	so	so	SCONJ
biomedich-274	172	14	there	there	PRON
biomedich-274	172	15	is	be	VERB
biomedich-274	172	16	no	no	DET
biomedich-274	172	17	need	need	NOUN
biomedich-274	172	18	for	for	ADP
biomedich-274	172	19	acknowledgement	acknowledgement	NOUN
biomedich-274	172	20	.	.	PUNCT
biomedich-274	173	1	authors	author	NOUN
biomedich-274	173	2	’	'	PUNCT
biomedich-274	173	3	contributions	contribution	NOUN
biomedich-274	173	4	:	:	PUNCT
biomedich-274	173	5	example	example	NOUN
biomedich-274	173	6	:	:	PUNCT
biomedich-274	173	7	ahsan	ahsan	PROPN
biomedich-274	173	8	ibrahim	ibrahim	PROPN
biomedich-274	173	9	designed	design	VERB
biomedich-274	173	10	the	the	DET
biomedich-274	173	11	study	study	NOUN
biomedich-274	173	12	.	.	PUNCT
biomedich-274	174	1	ahsan	ahsan	PROPN
biomedich-274	174	2	ibrahim	ibrahim	PROPN
biomedich-274	174	3	carried	carry	VERB
biomedich-274	174	4	out	out	ADP
biomedich-274	174	5	the	the	DET
biomedich-274	174	6	computational	computational	ADJ
biomedich-274	174	7	work	work	NOUN
biomedich-274	174	8	.	.	PUNCT
biomedich-274	175	1	ahsan	ahsan	PROPN
biomedich-274	175	2	ibrahim	ibrahim	PROPN
biomedich-274	175	3	&	&	CCONJ
biomedich-274	175	4	ehtisham	ehtisham	PROPN
biomedich-274	175	5	ul	ul	PROPN
biomedich-274	175	6	haq	haq	PROPN
biomedich-274	175	7	wrote	write	VERB
biomedich-274	175	8	the	the	DET
biomedich-274	175	9	manuscript	manuscript	NOUN
biomedich-274	175	10	.	.	PUNCT
biomedich-274	176	1	all	all	DET
biomedich-274	176	2	authors	author	NOUN
biomedich-274	176	3	read	read	VERB
biomedich-274	176	4	and	and	CCONJ
biomedich-274	176	5	approved	approve	VERB
biomedich-274	176	6	the	the	DET
biomedich-274	176	7	final	final	ADJ
biomedich-274	176	8	version	version	NOUN
biomedich-274	176	9	of	of	ADP
biomedich-274	176	10	the	the	DET
biomedich-274	176	11	manuscript	manuscript	NOUN
biomedich-274	176	12	competing	compete	VERB
biomedich-274	176	13	interests	interest	NOUN
biomedich-274	176	14	:	:	PUNCT
biomedich-274	176	15	there	there	PRON
biomedich-274	176	16	exist	exist	VERB
biomedich-274	176	17	no	no	DET
biomedich-274	176	18	competing	compete	VERB
biomedich-274	176	19	interests	interest	NOUN
biomedich-274	176	20	.	.	PUNCT
biomedich-274	177	1	references	reference	NOUN
biomedich-274	177	2	abdulai	abdulai	PROPN
biomedich-274	177	3	,	,	PUNCT
biomedich-274	177	4	ibrahim	ibrahim	PROPN
biomedich-274	177	5	luru	luru	PROPN
biomedich-274	177	6	,	,	PUNCT
biomedich-274	177	7	samuel	samuel	PROPN
biomedich-274	177	8	kojo	kojo	PROPN
biomedich-274	177	9	kwofie	kwofie	PROPN
biomedich-274	177	10	,	,	PUNCT
biomedich-274	177	11	winfred	winfre	VERB
biomedich-274	177	12	seth	seth	PROPN
biomedich-274	177	13	gbewonyo	gbewonyo	PROPN
biomedich-274	177	14	,	,	PUNCT
biomedich-274	177	15	daniel	daniel	PROPN
biomedich-274	177	16	boison	boison	PROPN
biomedich-274	177	17	,	,	PUNCT
biomedich-274	177	18	joshua	joshua	PROPN
biomedich-274	177	19	buer	buer	PROPN
biomedich-274	177	20	puplampu	puplampu	PROPN
biomedich-274	177	21	,	,	PUNCT
biomedich-274	177	22	and	and	CCONJ
biomedich-274	177	23	michael	michael	PROPN
biomedich-274	177	24	buenor	buenor	PROPN
biomedich-274	177	25	adinortey	adinortey	PROPN
biomedich-274	177	26	.	.	PUNCT
biomedich-274	178	1	2021	2021	NUM
biomedich-274	178	2	.	.	PUNCT
biomedich-274	179	1	“	"	PUNCT
biomedich-274	179	2	multitargeted	multitargete	VERB
biomedich-274	179	3	effects	effect	NOUN
biomedich-274	179	4	of	of	ADP
biomedich-274	179	5	vitexin	vitexin	NOUN
biomedich-274	179	6	and	and	CCONJ
biomedich-274	179	7	isovitexin	isovitexin	NOUN
biomedich-274	179	8	on	on	ADP
biomedich-274	179	9	diabetes	diabetes	NOUN
biomedich-274	179	10	mellitus	mellitus	NOUN
biomedich-274	179	11	and	and	CCONJ
biomedich-274	179	12	its	its	PRON
biomedich-274	179	13	complications	complication	NOUN
biomedich-274	179	14	.	.	PUNCT
biomedich-274	179	15	”	"	PUNCT
biomedich-274	180	1	the	the	DET
biomedich-274	180	2	scientific	scientific	ADJ
biomedich-274	180	3	world	world	NOUN
biomedich-274	180	4	journal	journal	PROPN
biomedich-274	180	5	2021	2021	NUM
biomedich-274	180	6	.	.	PUNCT
biomedich-274	181	1	https://doi.org/10.1155/2021/6641128	https://doi.org/10.1155/2021/6641128	PROPN
biomedich-274	181	2	.	.	PUNCT
biomedich-274	182	1	ahmad	ahmad	PROPN
biomedich-274	182	2	,	,	PUNCT
biomedich-274	182	3	iqrar	iqrar	PROPN
biomedich-274	182	4	,	,	PUNCT
biomedich-274	182	5	rahul	rahul	PROPN
biomedich-274	182	6	pawara	pawara	NOUN
biomedich-274	182	7	,	,	PUNCT
biomedich-274	182	8	sanjay	sanjay	PROPN
biomedich-274	182	9	surana	surana	PROPN
biomedich-274	182	10	,	,	PUNCT
biomedich-274	182	11	and	and	CCONJ
biomedich-274	182	12	harun	harun	PROPN
biomedich-274	182	13	patel	patel	PROPN
biomedich-274	182	14	.	.	PUNCT
biomedich-274	182	15	2021	2021	NUM
biomedich-274	182	16	.	.	PUNCT
biomedich-274	183	1	“	"	PUNCT
biomedich-274	183	2	the	the	DET
biomedich-274	183	3	repurposed	repurpose	VERB
biomedich-274	183	4	ace2	ace2	NOUN
biomedich-274	183	5	inhibitors	inhibitor	NOUN
biomedich-274	183	6	:	:	PUNCT
biomedich-274	183	7	sars	sar	NOUN
biomedich-274	183	8	-	-	PUNCT
biomedich-274	183	9	cov-2	cov-2	PART
biomedich-274	183	10	entry	entry	NOUN
biomedich-274	183	11	blockers	blocker	NOUN
biomedich-274	183	12	of	of	ADP
biomedich-274	183	13	covid-19	covid-19	PROPN
biomedich-274	183	14	.	.	PUNCT
biomedich-274	183	15	”	"	PUNCT
biomedich-274	184	1	topics	topic	NOUN
biomedich-274	184	2	in	in	ADP
biomedich-274	184	3	current	current	ADJ
biomedich-274	184	4	chemistry	chemistry	NOUN
biomedich-274	184	5	(	(	PUNCT
biomedich-274	184	6	cham	cham	PROPN
biomedich-274	184	7	)	)	PUNCT
biomedich-274	184	8	379	379	NUM
biomedich-274	184	9	(	(	PUNCT
biomedich-274	184	10	6	6	NUM
biomedich-274	184	11	)	)	PUNCT
biomedich-274	184	12	.	.	PUNCT
biomedich-274	185	1	https://doi.org/10.1007/s41061-021-00353-7	https://doi.org/10.1007/s41061-021-00353-7	PROPN
biomedich-274	185	2	.	.	PUNCT
biomedich-274	186	1	akkız	akkız	PROPN
biomedich-274	186	2	,	,	PUNCT
biomedich-274	186	3	hikmet	hikmet	PROPN
biomedich-274	186	4	.	.	PUNCT
biomedich-274	186	5	2022	2022	NUM
biomedich-274	186	6	.	.	PUNCT
biomedich-274	187	1	“	"	PUNCT
biomedich-274	187	2	the	the	DET
biomedich-274	187	3	biological	biological	ADJ
biomedich-274	187	4	functions	function	NOUN
biomedich-274	187	5	and	and	CCONJ
biomedich-274	187	6	clinical	clinical	ADJ
biomedich-274	187	7	significance	significance	NOUN
biomedich-274	187	8	of	of	ADP
biomedich-274	187	9	sars	sar	NOUN
biomedich-274	187	10	-	-	PUNCT
biomedich-274	187	11	cov-2	cov-2	NOUN
biomedich-274	187	12	variants	variant	NOUN
biomedich-274	187	13	of	of	ADP
biomedich-274	187	14	corcern	corcern	NOUN
biomedich-274	187	15	.	.	PUNCT
biomedich-274	187	16	”	"	PUNCT
biomedich-274	187	17	frontiers	frontier	NOUN
biomedich-274	187	18	in	in	ADP
biomedich-274	187	19	medicine	medicine	NOUN
biomedich-274	187	20	9	9	NUM
biomedich-274	187	21	(	(	PUNCT
biomedich-274	187	22	may	may	PROPN
biomedich-274	187	23	)	)	PUNCT
biomedich-274	187	24	.	.	PUNCT
biomedich-274	188	1	https://doi.org/10.3389/fmed.2022.849217	https://doi.org/10.3389/fmed.2022.849217	PROPN
biomedich-274	188	2	.	.	PUNCT
biomedich-274	189	1	“	"	PUNCT
biomedich-274	189	2	apigenin	apigenin	ADJ
biomedich-274	189	3	7	7	NUM
biomedich-274	189	4	-	-	PUNCT
biomedich-274	189	5	o	o	NOUN
biomedich-274	189	6	-	-	ADJ
biomedich-274	189	7	beta	beta	NOUN
biomedich-274	189	8	-	-	PUNCT
biomedich-274	189	9	d	d	NOUN
biomedich-274	189	10	-	-	PUNCT
biomedich-274	189	11	glucoside	glucoside	NOUN
biomedich-274	189	12	|	|	NOUN
biomedich-274	189	13	c21h20o10	c21h20o10	VERB
biomedich-274	189	14	pubchem	pubchem	NOUN
biomedich-274	189	15	.	.	PUNCT
biomedich-274	189	16	”	"	PUNCT
biomedich-274	190	1	n.d	n.d	PROPN
biomedich-274	190	2	.	.	PROPN
biomedich-274	190	3	accessed	access	VERB
biomedich-274	190	4	september	september	PROPN
biomedich-274	190	5	13	13	NUM
biomedich-274	190	6	,	,	PUNCT
biomedich-274	190	7	2022	2022	NUM
biomedich-274	190	8	.	.	PUNCT
biomedich-274	191	1	https://pubchem.ncbi.nlm.nih.gov/compound/apigenin-7-obeta-d-glucoside	https://pubchem.ncbi.nlm.nih.gov/compound/apigenin-7-obeta-d-glucoside	NOUN
biomedich-274	191	2	.	.	PUNCT
biomedich-274	192	1	“	"	PUNCT
biomedich-274	192	2	baicalin	baicalin	NOUN
biomedich-274	192	3	|	|	ADV
biomedich-274	192	4	c21h18o11	c21h18o11	PROPN
biomedich-274	192	5	pubchem	pubchem	NOUN
biomedich-274	192	6	.	.	PUNCT
biomedich-274	192	7	”	"	PUNCT
biomedich-274	193	1	n.d	n.d	PROPN
biomedich-274	193	2	.	.	PROPN
biomedich-274	193	3	accessed	access	VERB
biomedich-274	193	4	september	september	PROPN
biomedich-274	193	5	13	13	NUM
biomedich-274	193	6	,	,	PUNCT
biomedich-274	193	7	2022	2022	NUM
biomedich-274	193	8	.	.	PUNCT
biomedich-274	194	1	https://pubchem.ncbi.nlm.nih.gov/compound/baicalin	https://pubchem.ncbi.nlm.nih.gov/compound/baicalin	PROPN
biomedich-274	194	2	.	.	PROPN
biomedich-274	194	3	brosnahan	brosnahan	PROPN
biomedich-274	194	4	,	,	PUNCT
biomedich-274	194	5	shari	shari	PROPN
biomedich-274	194	6	b.	b.	PROPN
biomedich-274	194	7	,	,	PUNCT
biomedich-274	194	8	annemijn	annemijn	PROPN
biomedich-274	194	9	h.	h.	PROPN
biomedich-274	194	10	jonkman	jonkman	PROPN
biomedich-274	194	11	,	,	PUNCT
biomedich-274	194	12	matthias	matthias	PROPN
biomedich-274	194	13	c.	c.	PROPN
biomedich-274	194	14	kugler	kugler	PROPN
biomedich-274	194	15	,	,	PUNCT
biomedich-274	194	16	john	john	PROPN
biomedich-274	194	17	s.	s.	PROPN
biomedich-274	194	18	munger	munger	PROPN
biomedich-274	194	19	,	,	PUNCT
biomedich-274	194	20	and	and	CCONJ
biomedich-274	194	21	david	david	PROPN
biomedich-274	194	22	a.	a.	PROPN
biomedich-274	194	23	kaufman	kaufman	PROPN
biomedich-274	194	24	.	.	PUNCT
biomedich-274	195	1	2020	2020	NUM
biomedich-274	195	2	.	.	PUNCT
biomedich-274	196	1	“	"	PUNCT
biomedich-274	196	2	covid-19	covid-19	PROPN
biomedich-274	196	3	and	and	CCONJ
biomedich-274	196	4	respiratory	respiratory	ADJ
biomedich-274	196	5	system	system	NOUN
biomedich-274	196	6	disorders	disorder	NOUN
biomedich-274	196	7	:	:	PUNCT
biomedich-274	196	8	current	current	ADJ
biomedich-274	196	9	knowledge	knowledge	NOUN
biomedich-274	196	10	,	,	PUNCT
biomedich-274	196	11	future	future	ADJ
biomedich-274	196	12	clinical	clinical	ADJ
biomedich-274	196	13	and	and	CCONJ
biomedich-274	196	14	translational	translational	ADJ
biomedich-274	196	15	research	research	NOUN
biomedich-274	196	16	questions	question	NOUN
biomedich-274	196	17	.	.	PUNCT
biomedich-274	196	18	”	"	PUNCT
biomedich-274	197	1	arteriosclerosis	arteriosclerosis	NOUN
biomedich-274	197	2	,	,	PUNCT
biomedich-274	197	3	thrombosis	thrombosis	NOUN
biomedich-274	197	4	,	,	PUNCT
biomedich-274	197	5	and	and	CCONJ
biomedich-274	197	6	vascular	vascular	ADJ
biomedich-274	197	7	biology	biology	NOUN
biomedich-274	197	8	40	40	NUM
biomedich-274	197	9	(	(	PUNCT
biomedich-274	197	10	11	11	NUM
biomedich-274	197	11	):	):	PUNCT
biomedich-274	197	12	2586–97	2586–97	NUM
biomedich-274	197	13	.	.	PUNCT
biomedich-274	198	1	https://doi.org/10.1161/atvbaha.120.314515	https://doi.org/10.1161/atvbaha.120.314515	NOUN
biomedich-274	198	2	.	.	PUNCT
biomedich-274	199	1	chen	chen	PROPN
biomedich-274	199	2	,	,	PUNCT
biomedich-274	199	3	yu	yu	PROPN
biomedich-274	199	4	,	,	PUNCT
biomedich-274	199	5	qianyun	qianyun	PROPN
biomedich-274	199	6	liu	liu	PROPN
biomedich-274	199	7	,	,	PUNCT
biomedich-274	199	8	and	and	CCONJ
biomedich-274	199	9	deyin	deyin	PROPN
biomedich-274	199	10	guo	guo	PROPN
biomedich-274	199	11	.	.	PUNCT
biomedich-274	199	12	2020	2020	NUM
biomedich-274	199	13	.	.	PUNCT
biomedich-274	200	1	“	"	PUNCT
biomedich-274	200	2	emerging	emerge	VERB
biomedich-274	200	3	coronaviruses	coronaviruse	NOUN
biomedich-274	200	4	:	:	PUNCT
biomedich-274	200	5	genome	genome	NOUN
biomedich-274	200	6	structure	structure	NOUN
biomedich-274	200	7	,	,	PUNCT
biomedich-274	200	8	replication	replication	NOUN
biomedich-274	200	9	,	,	PUNCT
biomedich-274	200	10	and	and	CCONJ
biomedich-274	200	11	pathogenesis	pathogenesis	NOUN
biomedich-274	200	12	.	.	PUNCT
biomedich-274	200	13	”	"	PUNCT
biomedich-274	201	1	journal	journal	NOUN
biomedich-274	201	2	of	of	ADP
biomedich-274	201	3	medical	medical	ADJ
biomedich-274	201	4	virology	virology	NOUN
biomedich-274	201	5	92	92	NUM
biomedich-274	201	6	(	(	PUNCT
biomedich-274	201	7	4	4	NUM
biomedich-274	201	8	):	):	PUNCT
biomedich-274	201	9	418–23	418–23	NUM
biomedich-274	201	10	.	.	PUNCT
biomedich-274	202	1	https://doi.org/10.1002/jmv.25681	https://doi.org/10.1002/jmv.25681	PROPN
biomedich-274	202	2	.	.	PUNCT
biomedich-274	203	1	daina	daina	PROPN
biomedich-274	203	2	,	,	PUNCT
biomedich-274	203	3	antoine	antoine	PROPN
biomedich-274	203	4	,	,	PUNCT
biomedich-274	203	5	olivier	olivier	PROPN
biomedich-274	203	6	michielin	michielin	PROPN
biomedich-274	203	7	,	,	PUNCT
biomedich-274	203	8	and	and	CCONJ
biomedich-274	203	9	vincent	vincent	PROPN
biomedich-274	203	10	zoete	zoete	PROPN
biomedich-274	203	11	.	.	PUNCT
biomedich-274	204	1	2017	2017	NUM
biomedich-274	204	2	.	.	PUNCT
biomedich-274	205	1	“	"	PUNCT
biomedich-274	205	2	swissadme	swissadme	NOUN
biomedich-274	205	3	:	:	PUNCT
biomedich-274	205	4	a	a	DET
biomedich-274	205	5	free	free	ADJ
biomedich-274	205	6	web	web	NOUN
biomedich-274	205	7	tool	tool	NOUN
biomedich-274	205	8	to	to	PART
biomedich-274	205	9	evaluate	evaluate	VERB
biomedich-274	205	10	pharmacokinetics	pharmacokinetic	NOUN
biomedich-274	205	11	,	,	PUNCT
biomedich-274	205	12	drug	drug	NOUN
biomedich-274	205	13	-	-	PUNCT
biomedich-274	205	14	likeness	likeness	NOUN
biomedich-274	205	15	and	and	CCONJ
biomedich-274	205	16	medicinal	medicinal	ADJ
biomedich-274	205	17	chemistry	chemistry	NOUN
biomedich-274	205	18	friendliness	friendliness	NOUN
biomedich-274	205	19	of	of	ADP
biomedich-274	205	20	small	small	ADJ
biomedich-274	205	21	molecules	molecule	NOUN
biomedich-274	205	22	.	.	PUNCT
biomedich-274	205	23	”	"	PUNCT
biomedich-274	206	1	scientific	scientific	ADJ
biomedich-274	206	2	reports	report	NOUN
biomedich-274	206	3	2017	2017	NUM
biomedich-274	206	4	7:1	7:1	NUM
biomedich-274	206	5	7	7	NUM
biomedich-274	206	6	(	(	PUNCT
biomedich-274	206	7	1	1	NUM
biomedich-274	206	8	):	):	PUNCT
biomedich-274	206	9	1–13	1–13	NOUN
biomedich-274	206	10	.	.	PUNCT
biomedich-274	207	1	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
biomedich-274	207	2	.	.	PUNCT
biomedich-274	208	1	“	"	PUNCT
biomedich-274	208	2	diosmin	diosmin	NOUN
biomedich-274	208	3	|	|	ADV
biomedich-274	208	4	c28h32o15	c28h32o15	PROPN
biomedich-274	208	5	pubchem	pubchem	NOUN
biomedich-274	208	6	.	.	PUNCT
biomedich-274	208	7	”	"	PUNCT
biomedich-274	209	1	n.d	n.d	PROPN
biomedich-274	209	2	.	.	PROPN
biomedich-274	209	3	accessed	access	VERB
biomedich-274	209	4	september	september	PROPN
biomedich-274	209	5	13	13	NUM
biomedich-274	209	6	,	,	PUNCT
biomedich-274	209	7	2022	2022	NUM
biomedich-274	209	8	.	.	PUNCT
biomedich-274	210	1	https://pubchem.ncbi.nlm.nih.gov/compound/diosmin	https://pubchem.ncbi.nlm.nih.gov/compound/diosmin	NOUN
biomedich-274	210	2	.	.	PROPN
biomedich-274	210	3	ekins	ekin	NOUN
biomedich-274	210	4	,	,	PUNCT
biomedich-274	210	5	s.	s.	PROPN
biomedich-274	210	6	,	,	PUNCT
biomedich-274	210	7	j.	j.	PROPN
biomedich-274	210	8	mestres	mestres	PROPN
biomedich-274	210	9	,	,	PUNCT
biomedich-274	210	10	and	and	CCONJ
biomedich-274	210	11	b.	b.	PROPN
biomedich-274	210	12	testa	testa	PROPN
biomedich-274	210	13	.	.	PUNCT
biomedich-274	210	14	2007	2007	NUM
biomedich-274	210	15	.	.	PUNCT
biomedich-274	211	1	“	"	PUNCT
biomedich-274	211	2	in	in	ADP
biomedich-274	211	3	silico	silico	NOUN
biomedich-274	211	4	pharmacology	pharmacology	NOUN
biomedich-274	211	5	for	for	ADP
biomedich-274	211	6	drug	drug	NOUN
biomedich-274	211	7	discovery	discovery	NOUN
biomedich-274	211	8	:	:	PUNCT
biomedich-274	211	9	methods	method	NOUN
biomedich-274	211	10	for	for	ADP
biomedich-274	211	11	virtual	virtual	ADJ
biomedich-274	211	12	ligand	ligand	NOUN
biomedich-274	211	13	screening	screening	NOUN
biomedich-274	211	14	and	and	CCONJ
biomedich-274	211	15	profiling	profiling	NOUN
biomedich-274	211	16	.	.	PUNCT
biomedich-274	211	17	”	"	PUNCT
biomedich-274	211	18	british	british	ADJ
biomedich-274	211	19	journal	journal	PROPN
biomedich-274	211	20	of	of	ADP
biomedich-274	211	21	pharmacology	pharmacology	NOUN
biomedich-274	211	22	152	152	NUM
biomedich-274	211	23	(	(	PUNCT
biomedich-274	211	24	1	1	NUM
biomedich-274	211	25	):	):	PUNCT
biomedich-274	211	26	9	9	NUM
biomedich-274	211	27	–	–	SYM
biomedich-274	211	28	20	20	NUM
biomedich-274	211	29	.	.	PUNCT
biomedich-274	212	1	https://doi.org/10.1038/sj.bjp.0707305	https://doi.org/10.1038/sj.bjp.0707305	NOUN
biomedich-274	212	2	.	.	PUNCT
biomedich-274	213	1	feldo	feldo	PROPN
biomedich-274	213	2	,	,	PUNCT
biomedich-274	213	3	marcin	marcin	PROPN
biomedich-274	213	4	,	,	PUNCT
biomedich-274	213	5	michał	michał	PROPN
biomedich-274	213	6	woźniak	woźniak	PROPN
biomedich-274	213	7	,	,	PUNCT
biomedich-274	213	8	magdalena	magdalena	PROPN
biomedich-274	213	9	wójciak	wójciak	PROPN
biomedich-274	213	10	-	-	PUNCT
biomedich-274	213	11	kosior	kosior	PROPN
biomedich-274	213	12	,	,	PUNCT
biomedich-274	213	13	ireneusz	ireneusz	PROPN
biomedich-274	213	14	sowa	sowa	PROPN
biomedich-274	213	15	,	,	PUNCT
biomedich-274	213	16	agata	agata	PROPN
biomedich-274	213	17	kot	kot	PROPN
biomedich-274	213	18	-	-	PUNCT
biomedich-274	213	19	waśik	waśik	PROPN
biomedich-274	213	20	,	,	PUNCT
biomedich-274	213	21	justyna	justyna	PROPN
biomedich-274	213	22	aszyk	aszyk	PROPN
biomedich-274	213	23	,	,	PUNCT
biomedich-274	213	24	jacek	jacek	PROPN
biomedich-274	213	25	bogucki	bogucki	PROPN
biomedich-274	213	26	,	,	PUNCT
biomedich-274	213	27	tomasz	tomasz	PROPN
biomedich-274	213	28	zubilewicz	zubilewicz	PROPN
biomedich-274	213	29	,	,	PUNCT
biomedich-274	213	30	and	and	CCONJ
biomedich-274	213	31	anna	anna	PROPN
biomedich-274	213	32	bogucka	bogucka	PROPN
biomedich-274	213	33	-	-	PUNCT
biomedich-274	213	34	kocka	kocka	NOUN
biomedich-274	213	35	.	.	PUNCT
biomedich-274	214	1	2018	2018	NUM
biomedich-274	214	2	.	.	PUNCT
biomedich-274	215	1	“	"	PUNCT
biomedich-274	215	2	influence	influence	NOUN
biomedich-274	215	3	of	of	ADP
biomedich-274	215	4	diosmin	diosmin	NOUN
biomedich-274	215	5	treatment	treatment	NOUN
biomedich-274	215	6	on	on	ADP
biomedich-274	215	7	the	the	DET
biomedich-274	215	8	level	level	NOUN
biomedich-274	215	9	of	of	ADP
biomedich-274	215	10	oxidative	oxidative	ADJ
biomedich-274	215	11	stress	stress	NOUN
biomedich-274	215	12	markers	marker	NOUN
biomedich-274	215	13	in	in	ADP
biomedich-274	215	14	patients	patient	NOUN
biomedich-274	215	15	with	with	ADP
biomedich-274	215	16	chronic	chronic	ADJ
biomedich-274	215	17	venous	venous	ADJ
biomedich-274	215	18	insufficiency	insufficiency	NOUN
biomedich-274	215	19	.	.	PUNCT
biomedich-274	215	20	”	"	PUNCT
biomedich-274	215	21	oxidative	oxidative	ADJ
biomedich-274	215	22	medicine	medicine	NOUN
biomedich-274	215	23	and	and	CCONJ
biomedich-274	215	24	cellular	cellular	ADJ
biomedich-274	215	25	longevity	longevity	NOUN
biomedich-274	215	26	2018	2018	NUM
biomedich-274	215	27	.	.	PUNCT
biomedich-274	216	1	https://doi.org/10.1155/2018/2561705	https://doi.org/10.1155/2018/2561705	NOUN
biomedich-274	216	2	.	.	PUNCT
biomedich-274	217	1	ferreira	ferreira	PROPN
biomedich-274	217	2	,	,	PUNCT
biomedich-274	217	3	leonardo	leonardo	PROPN
biomedich-274	217	4	g.	g.	PROPN
biomedich-274	217	5	,	,	PUNCT
biomedich-274	217	6	ricardo	ricardo	PROPN
biomedich-274	217	7	n.	n.	PROPN
biomedich-274	217	8	dos	dos	PROPN
biomedich-274	217	9	santos	santos	PROPN
biomedich-274	217	10	,	,	PUNCT
biomedich-274	217	11	glaucius	glaucius	PROPN
biomedich-274	217	12	oliva	oliva	NOUN
biomedich-274	217	13	,	,	PUNCT
biomedich-274	217	14	and	and	CCONJ
biomedich-274	217	15	adriano	adriano	PROPN
biomedich-274	217	16	d.	d.	PROPN
biomedich-274	217	17	andricopulo	andricopulo	PROPN
biomedich-274	217	18	.	.	PUNCT
biomedich-274	218	1	2015	2015	NUM
biomedich-274	218	2	.	.	PUNCT
biomedich-274	219	1	“	"	PUNCT
biomedich-274	219	2	molecular	molecular	ADJ
biomedich-274	219	3	docking	docking	NOUN
biomedich-274	219	4	and	and	CCONJ
biomedich-274	219	5	structure	structure	NOUN
biomedich-274	219	6	-	-	PUNCT
biomedich-274	219	7	based	base	VERB
biomedich-274	219	8	drug	drug	NOUN
biomedich-274	219	9	design	design	NOUN
biomedich-274	219	10	strategies	strategy	NOUN
biomedich-274	219	11	.	.	PUNCT
biomedich-274	219	12	”	"	PUNCT
biomedich-274	220	1	molecules	molecule	NOUN
biomedich-274	220	2	2015	2015	NUM
biomedich-274	220	3	,	,	PUNCT
biomedich-274	220	4	vol	vol	NOUN
biomedich-274	220	5	.	.	PROPN
biomedich-274	220	6	20	20	NUM
biomedich-274	220	7	,	,	PUNCT
biomedich-274	220	8	pages	page	NOUN
biomedich-274	220	9	13384	13384	NUM
biomedich-274	220	10	-	-	SYM
biomedich-274	220	11	13421	13421	NUM
biomedich-274	220	12	20	20	NUM
biomedich-274	220	13	(	(	PUNCT
biomedich-274	220	14	7	7	NUM
biomedich-274	220	15	):	):	PUNCT
biomedich-274	220	16	13384–421	13384–421	NOUN
biomedich-274	220	17	.	.	PUNCT
biomedich-274	221	1	https://doi.org/10.3390/molecules200713384	https://doi.org/10.3390/molecules200713384	PROPN
biomedich-274	221	2	.	.	PUNCT
biomedich-274	222	1	hughes	hughes	PROPN
biomedich-274	222	2	,	,	PUNCT
biomedich-274	222	3	j.	j.	PROPN
biomedich-274	222	4	p.	p.	PROPN
biomedich-274	222	5	,	,	PUNCT
biomedich-274	222	6	s.	s.	PROPN
biomedich-274	222	7	s.	s.	PROPN
biomedich-274	222	8	rees	rees	PROPN
biomedich-274	222	9	,	,	PUNCT
biomedich-274	222	10	s.	s.	PROPN
biomedich-274	222	11	b.	b.	PROPN
biomedich-274	222	12	kalindjian	kalindjian	PROPN
biomedich-274	222	13	,	,	PUNCT
biomedich-274	222	14	and	and	CCONJ
biomedich-274	222	15	k.	k.	PROPN
biomedich-274	222	16	l.	l.	PROPN
biomedich-274	222	17	philpott	philpott	PROPN
biomedich-274	222	18	.	.	PUNCT
biomedich-274	222	19	2011	2011	NUM
biomedich-274	222	20	.	.	PUNCT
biomedich-274	223	1	“	"	PUNCT
biomedich-274	223	2	principles	principle	NOUN
biomedich-274	223	3	of	of	ADP
biomedich-274	223	4	early	early	ADJ
biomedich-274	223	5	drug	drug	NOUN
biomedich-274	223	6	discovery	discovery	NOUN
biomedich-274	223	7	.	.	PUNCT
biomedich-274	223	8	”	"	PUNCT
biomedich-274	224	1	british	british	ADJ
biomedich-274	224	2	journal	journal	PROPN
biomedich-274	224	3	of	of	ADP
biomedich-274	224	4	pharmacology	pharmacology	NOUN
biomedich-274	224	5	162	162	NUM
biomedich-274	224	6	(	(	PUNCT
biomedich-274	224	7	6	6	NUM
biomedich-274	224	8	):	):	PUNCT
biomedich-274	224	9	1239	1239	NUM
biomedich-274	224	10	.	.	PUNCT
biomedich-274	225	1	https://doi.org/10.1111/j.1476-5381.2010.01127.x	https://doi.org/10.1111/j.1476-5381.2010.01127.x	PROPN
biomedich-274	225	2	.	.	PUNCT
biomedich-274	226	1	hu	hu	PROPN
biomedich-274	226	2	,	,	PUNCT
biomedich-274	226	3	zhihua	zhihua	PROPN
biomedich-274	226	4	,	,	PUNCT
biomedich-274	226	5	yurong	yurong	PROPN
biomedich-274	226	6	guan	guan	PROPN
biomedich-274	226	7	,	,	PUNCT
biomedich-274	226	8	wanying	wanye	VERB
biomedich-274	226	9	hu	hu	PROPN
biomedich-274	226	10	,	,	PUNCT
biomedich-274	226	11	zhiyong	zhiyong	NOUN
biomedich-274	226	12	xu	xu	PROPN
biomedich-274	226	13	,	,	PUNCT
biomedich-274	226	14	and	and	CCONJ
biomedich-274	226	15	muhammad	muhammad	PROPN
biomedich-274	226	16	ishfaq	ishfaq	NOUN
biomedich-274	226	17	.	.	PUNCT
biomedich-274	227	1	2022	2022	NUM
biomedich-274	227	2	.	.	PUNCT
biomedich-274	228	1	“	"	PUNCT
biomedich-274	228	2	an	an	DET
biomedich-274	228	3	overview	overview	NOUN
biomedich-274	228	4	of	of	ADP
biomedich-274	228	5	pharmacological	pharmacological	ADJ
biomedich-274	228	6	activities	activity	NOUN
biomedich-274	228	7	of	of	ADP
biomedich-274	228	8	baicalin	baicalin	NOUN
biomedich-274	228	9	and	and	CCONJ
biomedich-274	228	10	its	its	PRON
biomedich-274	228	11	aglycone	aglycone	NOUN
biomedich-274	228	12	baicalein	baicalein	NOUN
biomedich-274	228	13	:	:	PUNCT
biomedich-274	228	14	new	new	ADJ
biomedich-274	228	15	insights	insight	NOUN
biomedich-274	228	16	into	into	ADP
biomedich-274	228	17	molecular	molecular	ADJ
biomedich-274	228	18	mechanisms	mechanism	NOUN
biomedich-274	228	19	and	and	CCONJ
biomedich-274	228	20	signaling	signal	VERB
biomedich-274	228	21	pathways	pathway	NOUN
biomedich-274	228	22	.	.	PUNCT
biomedich-274	228	23	”	"	PUNCT
biomedich-274	229	1	iranian	iranian	ADJ
biomedich-274	229	2	journal	journal	PROPN
biomedich-274	229	3	of	of	ADP
biomedich-274	229	4	basic	basic	ADJ
biomedich-274	229	5	medical	medical	ADJ
biomedich-274	229	6	sciences	science	NOUN
biomedich-274	229	7	25	25	NUM
biomedich-274	229	8	(	(	PUNCT
biomedich-274	229	9	1	1	NUM
biomedich-274	229	10	):	):	PUNCT
biomedich-274	229	11	14	14	NUM
biomedich-274	229	12	.	.	PUNCT
biomedich-274	229	13	https://doi.org/10.22038/ijbms.2022.60380.13381	https://doi.org/10.22038/ijbms.2022.60380.13381	NUM
biomedich-274	229	14	.	.	PUNCT
biomedich-274	230	1	“	"	PUNCT
biomedich-274	230	2	isoorientin	isoorientin	ADJ
biomedich-274	230	3	|	|	NOUN
biomedich-274	230	4	c21h20o11	c21h20o11	PROPN
biomedich-274	230	5	pubchem	pubchem	NOUN
biomedich-274	230	6	.	.	PUNCT
biomedich-274	230	7	”	"	PUNCT
biomedich-274	231	1	n.d	n.d	PROPN
biomedich-274	231	2	.	.	PROPN
biomedich-274	231	3	accessed	access	VERB
biomedich-274	231	4	september	september	PROPN
biomedich-274	231	5	13	13	NUM
biomedich-274	231	6	,	,	PUNCT
biomedich-274	231	7	2022	2022	NUM
biomedich-274	231	8	.	.	PUNCT
biomedich-274	232	1	https://pubchem.ncbi.nlm.nih.gov/compound/isoorientin	https://pubchem.ncbi.nlm.nih.gov/compound/isoorientin	X
biomedich-274	232	2	.	.	PUNCT
biomedich-274	233	1	“	"	PUNCT
biomedich-274	233	2	isovitexin	isovitexin	NOUN
biomedich-274	233	3	|	|	ADV
biomedich-274	233	4	c21h20o10	c21h20o10	VERB
biomedich-274	233	5	pubchem	pubchem	NOUN
biomedich-274	233	6	.	.	PUNCT
biomedich-274	233	7	”	"	PUNCT
biomedich-274	234	1	n.d	n.d	PROPN
biomedich-274	234	2	.	.	PROPN
biomedich-274	234	3	accessed	access	VERB
biomedich-274	234	4	september	september	PROPN
biomedich-274	234	5	13	13	NUM
biomedich-274	234	6	,	,	PUNCT
biomedich-274	234	7	2022	2022	NUM
biomedich-274	234	8	.	.	PUNCT
biomedich-274	235	1	https://pubchem.ncbi.nlm.nih.gov/compound/isovitexin	https://pubchem.ncbi.nlm.nih.gov/compound/isovitexin	PROPN
biomedich-274	235	2	.	.	PUNCT
biomedich-274	236	1	kai	kai	PROPN
biomedich-274	236	2	,	,	PUNCT
biomedich-274	236	3	hisashi	hisashi	PROPN
biomedich-274	236	4	,	,	PUNCT
biomedich-274	236	5	and	and	CCONJ
biomedich-274	236	6	mamiko	mamiko	NOUN
biomedich-274	236	7	kai	kai	PROPN
biomedich-274	236	8	.	.	PROPN
biomedich-274	236	9	2020	2020	NUM
biomedich-274	236	10	.	.	PUNCT
biomedich-274	237	1	“	"	PUNCT
biomedich-274	237	2	interactions	interaction	NOUN
biomedich-274	237	3	of	of	ADP
biomedich-274	237	4	coronaviruses	coronaviruse	NOUN
biomedich-274	237	5	with	with	ADP
biomedich-274	237	6	ace2	ace2	PROPN
biomedich-274	237	7	,	,	PUNCT
biomedich-274	237	8	angiotensin	angiotensin	NOUN
biomedich-274	237	9	ii	ii	PROPN
biomedich-274	237	10	,	,	PUNCT
biomedich-274	237	11	and	and	CCONJ
biomedich-274	237	12	ras	ras	X
biomedich-274	237	13	inhibitors	inhibitor	NOUN
biomedich-274	237	14	—	—	PUNCT
biomedich-274	237	15	lessons	lesson	NOUN
biomedich-274	237	16	from	from	ADP
biomedich-274	237	17	available	available	ADJ
biomedich-274	237	18	evidence	evidence	NOUN
biomedich-274	237	19	and	and	CCONJ
biomedich-274	237	20	insights	insight	NOUN
biomedich-274	237	21	into	into	ADP
biomedich-274	237	22	covid-19	covid-19	PROPN
biomedich-274	237	23	.	.	PUNCT
biomedich-274	237	24	”	"	PUNCT
biomedich-274	237	25	hypertension	hypertension	NOUN
biomedich-274	237	26	research	research	NOUN
biomedich-274	237	27	2020	2020	NUM
biomedich-274	237	28	43:7	43:7	NUM
biomedich-274	237	29	43	43	NUM
biomedich-274	237	30	(	(	PUNCT
biomedich-274	237	31	7	7	NUM
biomedich-274	237	32	):	):	PUNCT
biomedich-274	237	33	648–54	648–54	NUM
biomedich-274	237	34	.	.	PUNCT
biomedich-274	238	1	https://doi.org/10.1038/s41440-020-0455-8	https://doi.org/10.1038/s41440-020-0455-8	NUM
biomedich-274	238	2	.	.	PUNCT
biomedich-274	239	1	kumar	kumar	PROPN
biomedich-274	239	2	,	,	PUNCT
biomedich-274	239	3	shashank	shashank	PROPN
biomedich-274	239	4	,	,	PUNCT
biomedich-274	239	5	and	and	CCONJ
biomedich-274	239	6	abhay	abhay	PROPN
biomedich-274	239	7	k.	k.	PROPN
biomedich-274	239	8	pandey	pandey	PROPN
biomedich-274	239	9	.	.	PROPN
biomedich-274	239	10	2013	2013	NUM
biomedich-274	239	11	.	.	PUNCT
biomedich-274	240	1	“	"	PUNCT
biomedich-274	240	2	chemistry	chemistry	NOUN
biomedich-274	240	3	and	and	CCONJ
biomedich-274	240	4	biological	biological	ADJ
biomedich-274	240	5	activities	activity	NOUN
biomedich-274	240	6	of	of	ADP
biomedich-274	240	7	flavonoids	flavonoid	NOUN
biomedich-274	240	8	:	:	PUNCT
biomedich-274	240	9	an	an	DET
biomedich-274	240	10	overview	overview	NOUN
biomedich-274	240	11	.	.	PUNCT
biomedich-274	240	12	”	"	PUNCT
biomedich-274	241	1	the	the	DET
biomedich-274	241	2	scientific	scientific	ADJ
biomedich-274	241	3	world	world	NOUN
biomedich-274	241	4	journal	journal	PROPN
biomedich-274	241	5	2013	2013	NUM
biomedich-274	241	6	.	.	PUNCT
biomedich-274	242	1	https://doi.org/10.1155/2013/162750	https://doi.org/10.1155/2013/162750	PROPN
biomedich-274	242	2	.	.	PUNCT
biomedich-274	243	1	laishram	laishram	PROPN
biomedich-274	243	2	,	,	PUNCT
biomedich-274	243	3	surbala	surbala	PROPN
biomedich-274	243	4	,	,	PUNCT
biomedich-274	243	5	dinesh	dinesh	PROPN
biomedich-274	243	6	singh	singh	PROPN
biomedich-274	243	7	moirangthem	moirangthem	PROPN
biomedich-274	243	8	,	,	PUNCT
biomedich-274	243	9	jagat	jagat	PROPN
biomedich-274	243	10	chandra	chandra	PROPN
biomedich-274	243	11	borah	borah	PROPN
biomedich-274	243	12	,	,	PUNCT
biomedich-274	243	13	bikas	bikas	PROPN
biomedich-274	243	14	chandra	chandra	PROPN
biomedich-274	243	15	pal	pal	PROPN
biomedich-274	243	16	,	,	PUNCT
biomedich-274	243	17	pankaj	pankaj	PROPN
biomedich-274	243	18	suman	suman	PROPN
biomedich-274	243	19	,	,	PUNCT
biomedich-274	243	20	satish	satish	PROPN
biomedich-274	243	21	kumar	kumar	PROPN
biomedich-274	243	22	gupta	gupta	PROPN
biomedich-274	243	23	,	,	PUNCT
biomedich-274	243	24	mohan	mohan	PROPN
biomedich-274	243	25	chandra	chandra	PROPN
biomedich-274	243	26	kalita	kalita	PROPN
biomedich-274	243	27	,	,	PUNCT
biomedich-274	243	28	and	and	CCONJ
biomedich-274	243	29	narayan	narayan	PROPN
biomedich-274	243	30	chandra	chandra	PROPN
biomedich-274	243	31	talukdar	talukdar	NOUN
biomedich-274	243	32	.	.	PUNCT
biomedich-274	244	1	2015	2015	NUM
biomedich-274	244	2	.	.	PUNCT
biomedich-274	245	1	“	"	PUNCT
biomedich-274	245	2	chrysin	chrysin	VERB
biomedich-274	245	3	rich	rich	ADJ
biomedich-274	245	4	scutellaria	scutellaria	NOUN
biomedich-274	245	5	discolor	discolor	NOUN
biomedich-274	245	6	colebr	colebr	NOUN
biomedich-274	245	7	.	.	PUNCT
biomedich-274	246	1	induces	induce	VERB
biomedich-274	246	2	cervical	cervical	ADJ
biomedich-274	246	3	cancer	cancer	NOUN
biomedich-274	246	4	cell	cell	NOUN
biomedich-274	246	5	death	death	NOUN
biomedich-274	246	6	via	via	ADP
biomedich-274	246	7	the	the	DET
biomedich-274	246	8	induction	induction	NOUN
biomedich-274	246	9	of	of	ADP
biomedich-274	246	10	cell	cell	NOUN
biomedich-274	246	11	cycle	cycle	NOUN
biomedich-274	246	12	arrest	arrest	NOUN
biomedich-274	246	13	and	and	CCONJ
biomedich-274	246	14	caspase	caspase	NOUN
biomedich-274	246	15	-	-	PUNCT
biomedich-274	246	16	dependent	dependent	ADJ
biomedich-274	246	17	apoptosis	apoptosis	NOUN
biomedich-274	246	18	.	.	PUNCT
biomedich-274	246	19	”	"	PUNCT
biomedich-274	247	1	life	life	NOUN
biomedich-274	247	2	sciences	science	NOUN
biomedich-274	247	3	143	143	NUM
biomedich-274	247	4	(	(	PUNCT
biomedich-274	247	5	december	december	PROPN
biomedich-274	247	6	):	):	PUNCT
biomedich-274	247	7	105–13	105–13	PROPN
biomedich-274	247	8	.	.	PUNCT
biomedich-274	248	1	https://doi.org/10.1016/j.lfs.2015.10.035	https://doi.org/10.1016/j.lfs.2015.10.035	PROPN
biomedich-274	248	2	.	.	PUNCT
biomedich-274	249	1	“	"	PUNCT
biomedich-274	249	2	lonicerin	lonicerin	NOUN
biomedich-274	249	3	|	|	ADV
biomedich-274	249	4	c27h30o15	c27h30o15	PROPN
biomedich-274	249	5	pubchem	pubchem	NOUN
biomedich-274	249	6	.	.	PUNCT
biomedich-274	249	7	”	"	PUNCT
biomedich-274	250	1	n.d	n.d	PROPN
biomedich-274	250	2	.	.	PROPN
biomedich-274	250	3	accessed	access	VERB
biomedich-274	250	4	september	september	PROPN
biomedich-274	250	5	13	13	NUM
biomedich-274	250	6	,	,	PUNCT
biomedich-274	250	7	2022	2022	NUM
biomedich-274	250	8	.	.	PUNCT
biomedich-274	251	1	https://pubchem.ncbi.nlm.nih.gov/compound/lonicerin	https://pubchem.ncbi.nlm.nih.gov/compound/lonicerin	PROPN
biomedich-274	251	2	.	.	PUNCT
biomedich-274	252	1	lopéz	lopéz	PROPN
biomedich-274	252	2	-	-	PUNCT
biomedich-274	252	3	blanco	blanco	PROPN
biomedich-274	252	4	,	,	PUNCT
biomedich-274	252	5	josé	josé	PROPN
biomedich-274	252	6	ramón	ramón	PROPN
biomedich-274	252	7	,	,	PUNCT
biomedich-274	252	8	josé	josé	PROPN
biomedich-274	252	9	ignacio	ignacio	PROPN
biomedich-274	252	10	garzón	garzón	PROPN
biomedich-274	252	11	,	,	PUNCT
biomedich-274	252	12	and	and	CCONJ
biomedich-274	252	13	pablo	pablo	PROPN
biomedich-274	252	14	chacón	chacón	PROPN
biomedich-274	252	15	.	.	PUNCT
biomedich-274	253	1	2011	2011	NUM
biomedich-274	253	2	.	.	PUNCT
biomedich-274	254	1	“	"	PUNCT
biomedich-274	254	2	imod	imod	X
biomedich-274	254	3	:	:	PUNCT
biomedich-274	254	4	multipurpose	multipurpose	NOUN
biomedich-274	254	5	normal	normal	ADJ
biomedich-274	254	6	mode	mode	NOUN
biomedich-274	254	7	analysis	analysis	NOUN
biomedich-274	254	8	in	in	ADP
biomedich-274	254	9	internal	internal	ADJ
biomedich-274	254	10	coordinates	coordinate	NOUN
biomedich-274	254	11	.	.	PUNCT
biomedich-274	254	12	”	"	PUNCT
biomedich-274	255	1	bioinformatics	bioinformatic	NOUN
biomedich-274	255	2	(	(	PUNCT
biomedich-274	255	3	oxford	oxford	PROPN
biomedich-274	255	4	,	,	PUNCT
biomedich-274	255	5	england	england	PROPN
biomedich-274	255	6	)	)	PUNCT
biomedich-274	255	7	27	27	NUM
biomedich-274	255	8	(	(	PUNCT
biomedich-274	255	9	20	20	NUM
biomedich-274	255	10	):	):	PUNCT
biomedich-274	255	11	2843–50	2843–50	NOUN
biomedich-274	255	12	.	.	PUNCT
biomedich-274	256	1	https://doi.org/10.1093/bioinformatics/btr497	https://doi.org/10.1093/bioinformatics/btr497	NOUN
biomedich-274	256	2	.	.	PUNCT
biomedich-274	257	1	“	"	PUNCT
biomedich-274	257	2	luteolin	luteolin	PROPN
biomedich-274	257	3	3’-glucoside	3’-glucoside	NUM
biomedich-274	257	4	|	|	ADV
biomedich-274	257	5	c21h20o11	c21h20o11	PROPN
biomedich-274	257	6	pubchem	pubchem	NOUN
biomedich-274	257	7	.	.	PUNCT
biomedich-274	257	8	”	"	PUNCT
biomedich-274	258	1	n.d	n.d	PROPN
biomedich-274	258	2	.	.	PROPN
biomedich-274	258	3	accessed	access	VERB
biomedich-274	258	4	september	september	PROPN
biomedich-274	258	5	13	13	NUM
biomedich-274	258	6	,	,	PUNCT
biomedich-274	258	7	2022	2022	NUM
biomedich-274	258	8	.	.	PUNCT
biomedich-274	259	1	108	108	NUM
biomedich-274	259	2	biology	biology	NOUN
biomedich-274	259	3	,	,	PUNCT
biomedich-274	259	4	medicine	medicine	NOUN
biomedich-274	259	5	,	,	PUNCT
biomedich-274	259	6	&	&	CCONJ
biomedich-274	259	7	natural	natural	ADJ
biomedich-274	259	8	product	product	NOUN
biomedich-274	259	9	chemistry	chemistry	NOUN
biomedich-274	259	10	12	12	NUM
biomedich-274	259	11	(	(	PUNCT
biomedich-274	259	12	1	1	NUM
biomedich-274	259	13	)	)	PUNCT
biomedich-274	259	14	,	,	PUNCT
biomedich-274	259	15	2023	2023	NUM
biomedich-274	259	16	:	:	PUNCT
biomedich-274	259	17	97	97	NUM
biomedich-274	259	18	-	-	SYM
biomedich-274	259	19	108	108	NUM
biomedich-274	259	20	https://pubchem.ncbi.nlm.nih.gov/compound/luteolin-3_glucoside	https://pubchem.ncbi.nlm.nih.gov/compound/luteolin-3_glucoside	NOUN
biomedich-274	259	21	.	.	PUNCT
biomedich-274	260	1	meng	meng	PROPN
biomedich-274	260	2	,	,	PUNCT
biomedich-274	260	3	xuan	xuan	PROPN
biomedich-274	260	4	-	-	PUNCT
biomedich-274	260	5	yu	yu	PROPN
biomedich-274	260	6	,	,	PUNCT
biomedich-274	260	7	hong	hong	PROPN
biomedich-274	260	8	-	-	PUNCT
biomedich-274	260	9	xing	xing	PROPN
biomedich-274	260	10	zhang	zhang	PROPN
biomedich-274	260	11	,	,	PUNCT
biomedich-274	260	12	mihaly	mihaly	NOUN
biomedich-274	260	13	mezei	mezei	NOUN
biomedich-274	260	14	,	,	PUNCT
biomedich-274	260	15	and	and	CCONJ
biomedich-274	260	16	meng	meng	PROPN
biomedich-274	260	17	cui	cui	PROPN
biomedich-274	260	18	.	.	PROPN
biomedich-274	260	19	2011	2011	NUM
biomedich-274	260	20	.	.	PUNCT
biomedich-274	261	1	“	"	PUNCT
biomedich-274	261	2	molecular	molecular	ADJ
biomedich-274	261	3	docking	docking	NOUN
biomedich-274	261	4	:	:	PUNCT
biomedich-274	261	5	a	a	DET
biomedich-274	261	6	powerful	powerful	ADJ
biomedich-274	261	7	approach	approach	NOUN
biomedich-274	261	8	for	for	ADP
biomedich-274	261	9	structure	structure	NOUN
biomedich-274	261	10	-	-	PUNCT
biomedich-274	261	11	based	base	VERB
biomedich-274	261	12	drug	drug	NOUN
biomedich-274	261	13	discovery	discovery	NOUN
biomedich-274	261	14	.	.	PUNCT
biomedich-274	261	15	”	"	PUNCT
biomedich-274	262	1	current	current	ADJ
biomedich-274	262	2	computer	computer	NOUN
biomedich-274	262	3	-	-	PUNCT
biomedich-274	262	4	aided	aid	VERB
biomedich-274	262	5	drug	drug	NOUN
biomedich-274	262	6	design	design	NOUN
biomedich-274	262	7	7	7	NUM
biomedich-274	262	8	(	(	PUNCT
biomedich-274	262	9	2	2	NUM
biomedich-274	262	10	):	):	PUNCT
biomedich-274	262	11	146	146	NUM
biomedich-274	262	12	.	.	PUNCT
biomedich-274	262	13	https://doi.org/10.2174/157340911795677602	https://doi.org/10.2174/157340911795677602	PROPN
biomedich-274	262	14	.	.	PUNCT
biomedich-274	262	15	nie	nie	PROPN
biomedich-274	262	16	,	,	PUNCT
biomedich-274	262	17	juan	juan	PROPN
biomedich-274	262	18	,	,	PUNCT
biomedich-274	262	19	hong	hong	PROPN
biomedich-274	262	20	-	-	PUNCT
biomedich-274	262	21	mei	mei	PROPN
biomedich-274	262	22	yang	yang	PROPN
biomedich-274	262	23	,	,	PUNCT
biomedich-274	262	24	chao	chao	PROPN
biomedich-274	262	25	-	-	PUNCT
biomedich-274	262	26	yue	yue	PROPN
biomedich-274	262	27	sun	sun	PROPN
biomedich-274	262	28	,	,	PUNCT
biomedich-274	262	29	yan	yan	PROPN
biomedich-274	262	30	-	-	PUNCT
biomedich-274	262	31	lu	lu	PROPN
biomedich-274	262	32	liu	liu	PROPN
biomedich-274	262	33	,	,	PUNCT
biomedich-274	262	34	jian	jian	PROPN
biomedich-274	262	35	-	-	PUNCT
biomedich-274	262	36	yi	yi	PROPN
biomedich-274	262	37	zhuo	zhuo	PROPN
biomedich-274	262	38	,	,	PUNCT
biomedich-274	262	39	zhen	zhen	PROPN
biomedich-274	262	40	-	-	PUNCT
biomedich-274	262	41	biao	biao	PROPN
biomedich-274	262	42	zhang	zhang	PROPN
biomedich-274	262	43	,	,	PUNCT
biomedich-274	262	44	xiao	xiao	PROPN
biomedich-274	262	45	-	-	PUNCT
biomedich-274	262	46	ping	ping	PROPN
biomedich-274	262	47	lai	lai	PROPN
biomedich-274	262	48	,	,	PUNCT
biomedich-274	262	49	zi	zi	PROPN
biomedich-274	262	50	-	-	PROPN
biomedich-274	262	51	ren	ren	PROPN
biomedich-274	262	52	su	su	PROPN
biomedich-274	262	53	,	,	PUNCT
biomedich-274	262	54	and	and	CCONJ
biomedich-274	262	55	yucui	yucui	PROPN
biomedich-274	262	56	li	li	PROPN
biomedich-274	262	57	.	.	PROPN
biomedich-274	262	58	2018	2018	NUM
biomedich-274	262	59	.	.	PUNCT
biomedich-274	263	1	“	"	PUNCT
biomedich-274	263	2	scutellarin	scutellarin	NOUN
biomedich-274	263	3	enhances	enhance	VERB
biomedich-274	263	4	antitumor	antitumor	NOUN
biomedich-274	263	5	effects	effect	NOUN
biomedich-274	263	6	and	and	CCONJ
biomedich-274	263	7	attenuates	attenuate	VERB
biomedich-274	263	8	the	the	DET
biomedich-274	263	9	toxicity	toxicity	NOUN
biomedich-274	263	10	of	of	ADP
biomedich-274	263	11	bleomycin	bleomycin	PROPN
biomedich-274	263	12	in	in	ADP
biomedich-274	263	13	h22	h22	PROPN
biomedich-274	263	14	ascites	ascite	NOUN
biomedich-274	263	15	tumorbearing	tumorbeare	VERB
biomedich-274	263	16	mice	mouse	NOUN
biomedich-274	263	17	.	.	PUNCT
biomedich-274	263	18	”	"	PUNCT
biomedich-274	263	19	frontiers	frontier	NOUN
biomedich-274	263	20	in	in	ADP
biomedich-274	263	21	pharmacology	pharmacology	NOUN
biomedich-274	263	22	9	9	NUM
biomedich-274	263	23	:	:	SYM
biomedich-274	263	24	615	615	NUM
biomedich-274	263	25	.	.	PUNCT
biomedich-274	264	1	https://doi.org/10.3389/fphar.2018.00615	https://doi.org/10.3389/fphar.2018.00615	PROPN
biomedich-274	264	2	.	.	PUNCT
biomedich-274	264	3	panche	panche	PROPN
biomedich-274	264	4	,	,	PUNCT
biomedich-274	264	5	a.	a.	NOUN
biomedich-274	264	6	n.	n.	PROPN
biomedich-274	264	7	,	,	PUNCT
biomedich-274	264	8	a.	a.	PROPN
biomedich-274	264	9	d.	d.	PROPN
biomedich-274	264	10	diwan	diwan	PROPN
biomedich-274	264	11	,	,	PUNCT
biomedich-274	264	12	and	and	CCONJ
biomedich-274	264	13	s.	s.	PROPN
biomedich-274	264	14	r.	r.	PROPN
biomedich-274	264	15	chandra	chandra	PROPN
biomedich-274	264	16	.	.	PROPN
biomedich-274	264	17	2016	2016	NUM
biomedich-274	264	18	.	.	PUNCT
biomedich-274	265	1	“	"	PUNCT
biomedich-274	265	2	flavonoids	flavonoid	NOUN
biomedich-274	265	3	:	:	PUNCT
biomedich-274	265	4	an	an	DET
biomedich-274	265	5	overview	overview	NOUN
biomedich-274	265	6	.	.	PUNCT
biomedich-274	265	7	”	"	PUNCT
biomedich-274	266	1	journal	journal	NOUN
biomedich-274	266	2	of	of	ADP
biomedich-274	266	3	nutritional	nutritional	ADJ
biomedich-274	266	4	science	science	NOUN
biomedich-274	266	5	5	5	NUM
biomedich-274	266	6	(	(	PUNCT
biomedich-274	266	7	january	january	PROPN
biomedich-274	266	8	):	):	PUNCT
biomedich-274	266	9	1–15	1–15	PROPN
biomedich-274	266	10	.	.	PUNCT
biomedich-274	267	1	https://doi.org/10.1017/jns.2016.41	https://doi.org/10.1017/jns.2016.41	NOUN
biomedich-274	267	2	.	.	PUNCT
biomedich-274	267	3	park	park	PROPN
biomedich-274	267	4	,	,	PUNCT
biomedich-274	267	5	chung	chung	PROPN
biomedich-274	267	6	mu	mu	PROPN
biomedich-274	267	7	,	,	PUNCT
biomedich-274	267	8	and	and	CCONJ
biomedich-274	267	9	young	young	ADJ
biomedich-274	267	10	sun	sun	NOUN
biomedich-274	267	11	song	song	NOUN
biomedich-274	267	12	.	.	PUNCT
biomedich-274	268	1	2019	2019	NUM
biomedich-274	268	2	.	.	PUNCT
biomedich-274	269	1	“	"	PUNCT
biomedich-274	269	2	luteolin	luteolin	PROPN
biomedich-274	269	3	and	and	CCONJ
biomedich-274	269	4	luteolin-7	luteolin-7	PROPN
biomedich-274	269	5	-	-	PUNCT
biomedich-274	269	6	o	o	NOUN
biomedich-274	269	7	-	-	ADJ
biomedich-274	269	8	glucoside	glucoside	NOUN
biomedich-274	269	9	protect	protect	NOUN
biomedich-274	269	10	against	against	ADP
biomedich-274	269	11	acute	acute	ADJ
biomedich-274	269	12	liver	liver	NOUN
biomedich-274	269	13	injury	injury	NOUN
biomedich-274	269	14	through	through	ADP
biomedich-274	269	15	regulation	regulation	NOUN
biomedich-274	269	16	of	of	ADP
biomedich-274	269	17	inflammatory	inflammatory	ADJ
biomedich-274	269	18	mediators	mediator	NOUN
biomedich-274	269	19	and	and	CCONJ
biomedich-274	269	20	antioxidative	antioxidative	ADJ
biomedich-274	269	21	enzymes	enzyme	NOUN
biomedich-274	269	22	in	in	ADP
biomedich-274	269	23	galn	galn	PROPN
biomedich-274	269	24	/	/	SYM
biomedich-274	269	25	lps	lps	PROPN
biomedich-274	269	26	-	-	PUNCT
biomedich-274	269	27	induced	induce	VERB
biomedich-274	269	28	hepatitic	hepatitic	ADJ
biomedich-274	269	29	icr	icr	PROPN
biomedich-274	269	30	mice	mice	NOUN
biomedich-274	269	31	.	.	PUNCT
biomedich-274	269	32	”	"	PUNCT
biomedich-274	269	33	nutrition	nutrition	NOUN
biomedich-274	269	34	research	research	NOUN
biomedich-274	269	35	and	and	CCONJ
biomedich-274	269	36	practice	practice	NOUN
biomedich-274	269	37	13	13	NUM
biomedich-274	269	38	(	(	PUNCT
biomedich-274	269	39	6	6	NUM
biomedich-274	269	40	):	):	PUNCT
biomedich-274	269	41	473	473	NUM
biomedich-274	269	42	.	.	PUNCT
biomedich-274	270	1	https://doi.org/10.4162/nrp.2019.13.6.473	https://doi.org/10.4162/nrp.2019.13.6.473	NOUN
biomedich-274	270	2	.	.	PUNCT
biomedich-274	271	1	sander	sander	PROPN
biomedich-274	271	2	,	,	PUNCT
biomedich-274	271	3	thomas	thomas	PROPN
biomedich-274	271	4	,	,	PUNCT
biomedich-274	271	5	joel	joel	PROPN
biomedich-274	271	6	freyss	freyss	PROPN
biomedich-274	271	7	,	,	PUNCT
biomedich-274	271	8	modest	modest	ADJ
biomedich-274	271	9	von	von	PROPN
biomedich-274	271	10	korff	korff	PROPN
biomedich-274	271	11	,	,	PUNCT
biomedich-274	271	12	and	and	CCONJ
biomedich-274	271	13	christian	christian	ADJ
biomedich-274	271	14	rufener	rufener	NOUN
biomedich-274	271	15	.	.	PUNCT
biomedich-274	272	1	2015	2015	NUM
biomedich-274	272	2	.	.	PUNCT
biomedich-274	273	1	“	"	PUNCT
biomedich-274	273	2	datawarrior	datawarrior	NOUN
biomedich-274	273	3	:	:	PUNCT
biomedich-274	273	4	an	an	DET
biomedich-274	273	5	open	open	ADJ
biomedich-274	273	6	-	-	PUNCT
biomedich-274	273	7	source	source	NOUN
biomedich-274	273	8	program	program	NOUN
biomedich-274	273	9	for	for	ADP
biomedich-274	273	10	chemistry	chemistry	NOUN
biomedich-274	273	11	aware	aware	ADJ
biomedich-274	273	12	data	data	NOUN
biomedich-274	273	13	visualization	visualization	NOUN
biomedich-274	273	14	and	and	CCONJ
biomedich-274	273	15	analysis	analysis	NOUN
biomedich-274	273	16	.	.	PUNCT
biomedich-274	273	17	”	"	PUNCT
biomedich-274	274	1	journal	journal	NOUN
biomedich-274	274	2	of	of	ADP
biomedich-274	274	3	chemical	chemical	ADJ
biomedich-274	274	4	information	information	NOUN
biomedich-274	274	5	and	and	CCONJ
biomedich-274	274	6	modeling	model	VERB
biomedich-274	274	7	55	55	NUM
biomedich-274	274	8	(	(	PUNCT
biomedich-274	274	9	2	2	NUM
biomedich-274	274	10	):	):	PUNCT
biomedich-274	274	11	460–73	460–73	X
biomedich-274	274	12	.	.	X
biomedich-274	274	13	https://doi.org/10.1021/ci500588j	https://doi.org/10.1021/ci500588j	NOUN
biomedich-274	274	14	.	.	PUNCT
biomedich-274	275	1	“	"	PUNCT
biomedich-274	275	2	scutellarin	scutellarin	VERB
biomedich-274	275	3	|	|	ADV
biomedich-274	275	4	c21h18o12	c21h18o12	VERB
biomedich-274	275	5	pubchem	pubchem	NOUN
biomedich-274	275	6	.	.	PUNCT
biomedich-274	275	7	”	"	PUNCT
biomedich-274	276	1	n.d	n.d	PROPN
biomedich-274	276	2	.	.	PROPN
biomedich-274	276	3	accessed	access	VERB
biomedich-274	276	4	september	september	PROPN
biomedich-274	276	5	13	13	NUM
biomedich-274	276	6	,	,	PUNCT
biomedich-274	276	7	2022	2022	NUM
biomedich-274	276	8	.	.	PUNCT
biomedich-274	277	1	https://pubchem.ncbi.nlm.nih.gov/compound/scutellarin	https://pubchem.ncbi.nlm.nih.gov/compound/scutellarin	PROPN
biomedich-274	277	2	.	.	PUNCT
biomedich-274	278	1	sternberg	sternberg	PROPN
biomedich-274	278	2	,	,	PUNCT
biomedich-274	278	3	ariane	ariane	PROPN
biomedich-274	278	4	,	,	PUNCT
biomedich-274	278	5	and	and	CCONJ
biomedich-274	278	6	cord	cord	NOUN
biomedich-274	278	7	naujokat	naujokat	NOUN
biomedich-274	278	8	.	.	PUNCT
biomedich-274	279	1	2020	2020	NUM
biomedich-274	279	2	.	.	PUNCT
biomedich-274	280	1	“	"	PUNCT
biomedich-274	280	2	structural	structural	ADJ
biomedich-274	280	3	features	feature	NOUN
biomedich-274	280	4	of	of	ADP
biomedich-274	280	5	coronavirus	coronavirus	NOUN
biomedich-274	280	6	sars	sar	NOUN
biomedich-274	280	7	-	-	PUNCT
biomedich-274	280	8	cov-2	cov-2	NOUN
biomedich-274	280	9	spike	spike	ADJ
biomedich-274	280	10	protein	protein	NOUN
biomedich-274	280	11	:	:	PUNCT
biomedich-274	280	12	targets	target	NOUN
biomedich-274	280	13	for	for	ADP
biomedich-274	280	14	vaccination	vaccination	NOUN
biomedich-274	280	15	.	.	PUNCT
biomedich-274	280	16	”	"	PUNCT
biomedich-274	281	1	life	life	NOUN
biomedich-274	281	2	sciences	science	NOUN
biomedich-274	281	3	257	257	NUM
biomedich-274	281	4	(	(	PUNCT
biomedich-274	281	5	september	september	PROPN
biomedich-274	281	6	):	):	PUNCT
biomedich-274	281	7	118056	118056	NUM
biomedich-274	281	8	.	.	PUNCT
biomedich-274	282	1	https://doi.org/10.1016/j.lfs.2020.118056	https://doi.org/10.1016/j.lfs.2020.118056	PROPN
biomedich-274	282	2	.	.	PUNCT
biomedich-274	283	1	“	"	PUNCT
biomedich-274	283	2	swertisin	swertisin	VERB
biomedich-274	283	3	|	|	ADV
biomedich-274	283	4	c22h22o10	c22h22o10	NOUN
biomedich-274	283	5	pubchem	pubchem	NOUN
biomedich-274	283	6	.	.	PUNCT
biomedich-274	283	7	”	"	PUNCT
biomedich-274	284	1	n.d	n.d	PROPN
biomedich-274	284	2	.	.	PROPN
biomedich-274	284	3	accessed	access	VERB
biomedich-274	284	4	september	september	PROPN
biomedich-274	284	5	13	13	NUM
biomedich-274	284	6	,	,	PUNCT
biomedich-274	284	7	2022	2022	NUM
biomedich-274	284	8	.	.	PUNCT
biomedich-274	285	1	https://pubchem.ncbi.nlm.nih.gov/compound/swertisin	https://pubchem.ncbi.nlm.nih.gov/compound/swertisin	PROPN
biomedich-274	285	2	.	.	PUNCT
biomedich-274	286	1	“	"	PUNCT
biomedich-274	286	2	swertisin	swertisin	VERB
biomedich-274	286	3	(	(	PUNCT
biomedich-274	286	4	chebi:131838	chebi:131838	NOUN
biomedich-274	286	5	)	)	PUNCT
biomedich-274	286	6	.	.	PUNCT
biomedich-274	286	7	”	"	PUNCT
biomedich-274	287	1	n.d	n.d	PROPN
biomedich-274	287	2	.	.	PROPN
biomedich-274	287	3	accessed	access	VERB
biomedich-274	287	4	september	september	PROPN
biomedich-274	287	5	15	15	NUM
biomedich-274	287	6	,	,	PUNCT
biomedich-274	287	7	2022	2022	NUM
biomedich-274	287	8	.	.	PUNCT
biomedich-274	288	1	https://www.ebi.ac.uk/chebi/chebiontology.do?chebiid=che	https://www.ebi.ac.uk/chebi/chebiontology.do?chebiid=che	PROPN
biomedich-274	288	2	bi:131838	bi:131838	PROPN
biomedich-274	288	3	.	.	PROPN
biomedich-274	288	4	towler	towler	PROPN
biomedich-274	288	5	,	,	PUNCT
biomedich-274	288	6	paul	paul	PROPN
biomedich-274	288	7	,	,	PUNCT
biomedich-274	288	8	bart	bart	PROPN
biomedich-274	288	9	staker	staker	PROPN
biomedich-274	288	10	,	,	PUNCT
biomedich-274	288	11	sridhar	sridhar	PROPN
biomedich-274	288	12	g.	g.	PROPN
biomedich-274	288	13	prasad	prasad	PROPN
biomedich-274	288	14	,	,	PUNCT
biomedich-274	288	15	saurabh	saurabh	PROPN
biomedich-274	288	16	menon	menon	PROPN
biomedich-274	288	17	,	,	PUNCT
biomedich-274	288	18	jin	jin	PROPN
biomedich-274	288	19	tang	tang	PROPN
biomedich-274	288	20	,	,	PUNCT
biomedich-274	288	21	thomas	thomas	PROPN
biomedich-274	288	22	parsons	parsons	PROPN
biomedich-274	288	23	,	,	PUNCT
biomedich-274	288	24	dominic	dominic	PROPN
biomedich-274	288	25	ryan	ryan	PROPN
biomedich-274	288	26	,	,	PUNCT
biomedich-274	288	27	et	et	PROPN
biomedich-274	288	28	al	al	PROPN
biomedich-274	288	29	.	.	PROPN
biomedich-274	288	30	2004a	2004a	NUM
biomedich-274	288	31	.	.	PUNCT
biomedich-274	289	1	“	"	PUNCT
biomedich-274	289	2	ace2	ace2	NOUN
biomedich-274	289	3	x	x	NOUN
biomedich-274	289	4	-	-	NOUN
biomedich-274	289	5	ray	ray	NOUN
biomedich-274	289	6	structures	structure	NOUN
biomedich-274	289	7	reveal	reveal	VERB
biomedich-274	289	8	a	a	DET
biomedich-274	289	9	large	large	ADJ
biomedich-274	289	10	hinge	hinge	NOUN
biomedich-274	289	11	-	-	PUNCT
biomedich-274	289	12	bending	bend	VERB
biomedich-274	289	13	motion	motion	NOUN
biomedich-274	289	14	important	important	ADJ
biomedich-274	289	15	for	for	ADP
biomedich-274	289	16	inhibitor	inhibitor	NOUN
biomedich-274	289	17	binding	bind	VERB
biomedich-274	289	18	and	and	CCONJ
biomedich-274	289	19	catalysis	catalysis	NOUN
biomedich-274	289	20	.	.	PUNCT
biomedich-274	289	21	”	"	PUNCT
biomedich-274	290	1	the	the	DET
biomedich-274	290	2	journal	journal	NOUN
biomedich-274	290	3	of	of	ADP
biomedich-274	290	4	biological	biological	ADJ
biomedich-274	290	5	chemistry	chemistry	NOUN
biomedich-274	290	6	279	279	NUM
biomedich-274	290	7	(	(	PUNCT
biomedich-274	290	8	17	17	NUM
biomedich-274	290	9	):	):	PUNCT
biomedich-274	290	10	17996–7	17996–7	PROPN
biomedich-274	290	11	.	.	PUNCT
biomedich-274	290	12	https://doi.org/10.1074/jbc.m311191200	https://doi.org/10.1074/jbc.m311191200	PROPN
biomedich-274	290	13	.	.	PUNCT
biomedich-274	291	1	_	_	PUNCT
biomedich-274	292	1	_	_	PUNCT
biomedich-274	293	1	_	_	PUNCT
biomedich-274	293	2	.	.	PUNCT
biomedich-274	294	1	2004b	2004b	NUM
biomedich-274	294	2	.	.	PUNCT
biomedich-274	295	1	“	"	PUNCT
biomedich-274	295	2	ace2	ace2	NOUN
biomedich-274	295	3	x	x	NOUN
biomedich-274	295	4	-	-	NOUN
biomedich-274	295	5	ray	ray	NOUN
biomedich-274	295	6	structures	structure	NOUN
biomedich-274	295	7	reveal	reveal	VERB
biomedich-274	295	8	a	a	DET
biomedich-274	295	9	large	large	ADJ
biomedich-274	295	10	hingebending	hingebende	VERB
biomedich-274	295	11	motion	motion	NOUN
biomedich-274	295	12	important	important	ADJ
biomedich-274	295	13	for	for	ADP
biomedich-274	295	14	inhibitor	inhibitor	NOUN
biomedich-274	295	15	binding	bind	VERB
biomedich-274	295	16	and	and	CCONJ
biomedich-274	295	17	catalysis	catalysis	NOUN
biomedich-274	295	18	.	.	PUNCT
biomedich-274	295	19	”	"	PUNCT
biomedich-274	296	1	the	the	DET
biomedich-274	296	2	journal	journal	NOUN
biomedich-274	296	3	of	of	ADP
biomedich-274	296	4	biological	biological	ADJ
biomedich-274	296	5	chemistry	chemistry	NOUN
biomedich-274	296	6	279	279	NUM
biomedich-274	296	7	(	(	PUNCT
biomedich-274	296	8	17	17	NUM
biomedich-274	296	9	):	):	PUNCT
biomedich-274	296	10	17996–7	17996–7	PROPN
biomedich-274	296	11	.	.	PUNCT
biomedich-274	296	12	https://doi.org/10.1074/jbc.m311191200	https://doi.org/10.1074/jbc.m311191200	PROPN
biomedich-274	296	13	.	.	PUNCT
biomedich-274	297	1	“	"	PUNCT
biomedich-274	297	2	tricin	tricin	VERB
biomedich-274	297	3	7	7	NUM
biomedich-274	297	4	-	-	PUNCT
biomedich-274	297	5	o	o	NOUN
biomedich-274	297	6	-	-	ADJ
biomedich-274	297	7	glucuronide	glucuronide	ADJ
biomedich-274	297	8	|	|	ADP
biomedich-274	297	9	c23h22o13	c23h22o13	PROPN
biomedich-274	297	10	pubchem	pubchem	NOUN
biomedich-274	297	11	.	.	PUNCT
biomedich-274	297	12	”	"	PUNCT
biomedich-274	298	1	n.d	n.d	PROPN
biomedich-274	298	2	.	.	PROPN
biomedich-274	298	3	accessed	access	VERB
biomedich-274	298	4	september	september	PROPN
biomedich-274	298	5	13	13	NUM
biomedich-274	298	6	,	,	PUNCT
biomedich-274	298	7	2022	2022	NUM
biomedich-274	298	8	.	.	PUNCT
biomedich-274	299	1	https://pubchem.ncbi.nlm.nih.gov/compound/tricin-7-oglucuronide	https://pubchem.ncbi.nlm.nih.gov/compound/tricin-7-oglucuronide	PROPN
biomedich-274	299	2	.	.	PUNCT
biomedich-274	300	1	wang	wang	PROPN
biomedich-274	300	2	,	,	PUNCT
biomedich-274	300	3	liping	liping	PROPN
biomedich-274	300	4	,	,	PUNCT
biomedich-274	300	5	and	and	CCONJ
biomedich-274	300	6	qiang	qiang	PROPN
biomedich-274	300	7	ma	ma	PROPN
biomedich-274	300	8	.	.	PROPN
biomedich-274	300	9	2018	2018	NUM
biomedich-274	300	10	.	.	PUNCT
biomedich-274	301	1	“	"	PUNCT
biomedich-274	301	2	clinical	clinical	ADJ
biomedich-274	301	3	benefits	benefit	NOUN
biomedich-274	301	4	and	and	CCONJ
biomedich-274	301	5	pharmacology	pharmacology	NOUN
biomedich-274	301	6	of	of	ADP
biomedich-274	301	7	scutellarin	scutellarin	NOUN
biomedich-274	301	8	:	:	PUNCT
biomedich-274	301	9	a	a	DET
biomedich-274	301	10	comprehensive	comprehensive	ADJ
biomedich-274	301	11	review	review	NOUN
biomedich-274	301	12	.	.	PUNCT
biomedich-274	301	13	”	"	PUNCT
biomedich-274	302	1	pharmacology	pharmacology	NOUN
biomedich-274	302	2	&	&	CCONJ
biomedich-274	302	3	therapeutics	therapeutic	NOUN
biomedich-274	302	4	190	190	NUM
biomedich-274	302	5	(	(	PUNCT
biomedich-274	302	6	october	october	PROPN
biomedich-274	302	7	):	):	PUNCT
biomedich-274	302	8	105–27	105–27	NUM
biomedich-274	302	9	.	.	PUNCT
biomedich-274	303	1	https://doi.org/10.1016/j.pharmthera.2018.05.006	https://doi.org/10.1016/j.pharmthera.2018.05.006	NOUN
biomedich-274	303	2	.	.	PUNCT
biomedich-274	304	1	“	"	PUNCT
biomedich-274	304	2	who	who	PRON
biomedich-274	304	3	coronavirus	coronavirus	VERB
biomedich-274	304	4	(	(	PUNCT
biomedich-274	304	5	covid-19	covid-19	PROPN
biomedich-274	304	6	)	)	PUNCT
biomedich-274	304	7	dashboard	dashboard	NOUN
biomedich-274	304	8	|	|	ADV
biomedich-274	304	9	who	who	PRON
biomedich-274	304	10	coronavirus	coronavirus	NOUN
biomedich-274	304	11	(	(	PUNCT
biomedich-274	304	12	covid-19	covid-19	PROPN
biomedich-274	304	13	)	)	PUNCT
biomedich-274	304	14	dashboard	dashboard	NOUN
biomedich-274	304	15	with	with	ADP
biomedich-274	304	16	vaccination	vaccination	NOUN
biomedich-274	304	17	data	datum	NOUN
biomedich-274	304	18	.	.	PUNCT
biomedich-274	304	19	”	"	PUNCT
biomedich-274	305	1	n.d	n.d	PROPN
biomedich-274	305	2	.	.	PROPN
biomedich-274	305	3	accessed	access	VERB
biomedich-274	305	4	september	september	PROPN
biomedich-274	305	5	21	21	NUM
biomedich-274	305	6	,	,	PUNCT
biomedich-274	305	7	2022	2022	NUM
biomedich-274	305	8	.	.	PUNCT
biomedich-274	306	1	https://covid19.who.int/.	https://covid19.who.int/.	ADJ
biomedich-274	306	2	wu	wu	PROPN
biomedich-274	306	3	,	,	PUNCT
biomedich-274	306	4	can	can	AUX
biomedich-274	306	5	rong	rong	PROPN
biomedich-274	306	6	,	,	PUNCT
biomedich-274	306	7	wan	wan	PROPN
biomedich-274	306	8	chao	chao	PROPN
biomedich-274	306	9	yin	yin	PROPN
biomedich-274	306	10	,	,	PUNCT
biomedich-274	306	11	yi	yi	PROPN
biomedich-274	306	12	jiang	jiang	PROPN
biomedich-274	306	13	,	,	PUNCT
biomedich-274	306	14	and	and	CCONJ
biomedich-274	306	15	h.	h.	PROPN
biomedich-274	306	16	eric	eric	PROPN
biomedich-274	306	17	xu	xu	PROPN
biomedich-274	306	18	.	.	PUNCT
biomedich-274	306	19	2022	2022	NUM
biomedich-274	306	20	.	.	PUNCT
biomedich-274	307	1	“	"	PUNCT
biomedich-274	307	2	structure	structure	NOUN
biomedich-274	307	3	genomics	genomic	NOUN
biomedich-274	307	4	of	of	ADP
biomedich-274	307	5	sars	sar	NOUN
biomedich-274	307	6	-	-	PUNCT
biomedich-274	307	7	cov-2	cov-2	NOUN
biomedich-274	307	8	and	and	CCONJ
biomedich-274	307	9	its	its	PRON
biomedich-274	307	10	omicron	omicron	PROPN
biomedich-274	307	11	variant	variant	NOUN
biomedich-274	307	12	:	:	PUNCT
biomedich-274	307	13	drug	drug	NOUN
biomedich-274	307	14	design	design	NOUN
biomedich-274	307	15	templates	template	NOUN
biomedich-274	307	16	for	for	ADP
biomedich-274	307	17	covid-19	covid-19	PROPN
biomedich-274	307	18	.	.	PUNCT
biomedich-274	307	19	”	"	PUNCT
biomedich-274	308	1	acta	acta	PROPN
biomedich-274	308	2	pharmacologica	pharmacologica	PROPN
biomedich-274	308	3	sinica	sinica	PROPN
biomedich-274	308	4	2022	2022	PROPN
biomedich-274	308	5	,	,	PUNCT
biomedich-274	308	6	january	january	PROPN
biomedich-274	308	7	,	,	PUNCT
biomedich-274	308	8	1–13	1–13	PROPN
biomedich-274	308	9	.	.	PUNCT
biomedich-274	309	1	https://doi.org/10.1038/s41401-021-00851-w	https://doi.org/10.1038/s41401-021-00851-w	PROPN
biomedich-274	309	2	.	.	PROPN
biomedich-274	310	1	xiao	xiao	PROPN
biomedich-274	310	2	,	,	PUNCT
biomedich-274	310	3	jianbo	jianbo	PROPN
biomedich-274	310	4	,	,	PUNCT
biomedich-274	310	5	esra	esra	PROPN
biomedich-274	310	6	capanoglu	capanoglu	PROPN
biomedich-274	310	7	,	,	PUNCT
biomedich-274	310	8	amir	amir	PROPN
biomedich-274	310	9	reza	reza	PROPN
biomedich-274	310	10	jassbi	jassbi	PROPN
biomedich-274	310	11	,	,	PUNCT
biomedich-274	310	12	and	and	CCONJ
biomedich-274	310	13	anca	anca	PROPN
biomedich-274	310	14	miron	miron	PROPN
biomedich-274	310	15	.	.	PUNCT
biomedich-274	311	1	2016	2016	NUM
biomedich-274	311	2	.	.	PUNCT
biomedich-274	312	1	“	"	PUNCT
biomedich-274	312	2	advance	advance	VERB
biomedich-274	312	3	on	on	ADP
biomedich-274	312	4	the	the	DET
biomedich-274	312	5	flavonoid	flavonoid	NOUN
biomedich-274	312	6	c	c	NOUN
biomedich-274	312	7	-	-	PUNCT
biomedich-274	312	8	glycosides	glycoside	NOUN
biomedich-274	312	9	and	and	CCONJ
biomedich-274	312	10	health	health	NOUN
biomedich-274	312	11	benefits	benefit	NOUN
biomedich-274	312	12	.	.	PUNCT
biomedich-274	312	13	”	"	PUNCT
biomedich-274	313	1	critical	critical	ADJ
biomedich-274	313	2	reviews	review	NOUN
biomedich-274	313	3	in	in	ADP
biomedich-274	313	4	food	food	NOUN
biomedich-274	313	5	science	science	NOUN
biomedich-274	313	6	and	and	CCONJ
biomedich-274	313	7	nutrition	nutrition	NOUN
biomedich-274	313	8	56	56	NUM
biomedich-274	313	9	suppl	suppl	ADJ
biomedich-274	313	10	1	1	NUM
biomedich-274	313	11	(	(	PUNCT
biomedich-274	313	12	july	july	PROPN
biomedich-274	313	13	):	):	PUNCT
biomedich-274	313	14	s29–45	s29–45	PROPN
biomedich-274	313	15	.	.	PUNCT
biomedich-274	314	1	https://doi.org/10.1080/10408398.2015.1067595	https://doi.org/10.1080/10408398.2015.1067595	PROPN
biomedich-274	314	2	.	.	PUNCT
biomedich-274	315	1	xu	xu	PROPN
biomedich-274	315	2	,	,	PUNCT
biomedich-274	315	3	zhongren	zhongren	PROPN
biomedich-274	315	4	,	,	PUNCT
biomedich-274	315	5	kun	kun	PROPN
biomedich-274	315	6	li	li	PROPN
biomedich-274	315	7	,	,	PUNCT
biomedich-274	315	8	taowen	taowen	NOUN
biomedich-274	315	9	pan	pan	PROPN
biomedich-274	315	10	,	,	PUNCT
biomedich-274	315	11	jing	jing	PROPN
biomedich-274	315	12	liu	liu	PROPN
biomedich-274	315	13	,	,	PUNCT
biomedich-274	315	14	bin	bin	PROPN
biomedich-274	315	15	li	li	PROPN
biomedich-274	315	16	,	,	PUNCT
biomedich-274	315	17	chuanxun	chuanxun	PROPN
biomedich-274	315	18	li	li	PROPN
biomedich-274	315	19	,	,	PUNCT
biomedich-274	315	20	shouyu	shouyu	PROPN
biomedich-274	315	21	wang	wang	PROPN
biomedich-274	315	22	,	,	PUNCT
biomedich-274	315	23	yunpeng	yunpeng	PROPN
biomedich-274	315	24	diao	diao	PROPN
biomedich-274	315	25	,	,	PUNCT
biomedich-274	315	26	and	and	CCONJ
biomedich-274	315	27	xinguang	xinguang	PROPN
biomedich-274	315	28	liu	liu	PROPN
biomedich-274	315	29	.	.	PROPN
biomedich-274	316	1	2019	2019	NUM
biomedich-274	316	2	.	.	PUNCT
biomedich-274	317	1	“	"	PUNCT
biomedich-274	317	2	lonicerin	lonicerin	NOUN
biomedich-274	317	3	,	,	PUNCT
biomedich-274	317	4	an	an	DET
biomedich-274	317	5	anti	anti	ADJ
biomedich-274	317	6	-	-	ADJ
biomedich-274	317	7	alge	alge	ADJ
biomedich-274	317	8	flavonoid	flavonoid	NOUN
biomedich-274	317	9	against	against	ADP
biomedich-274	317	10	pseudomonas	pseudomona	NOUN
biomedich-274	317	11	aeruginosa	aeruginosa	NOUN
biomedich-274	317	12	virulence	virulence	NOUN
biomedich-274	317	13	screened	screen	VERB
biomedich-274	317	14	from	from	ADP
biomedich-274	317	15	shuanghuanglian	shuanghuanglian	ADJ
biomedich-274	317	16	formula	formula	NOUN
biomedich-274	317	17	by	by	ADP
biomedich-274	317	18	molecule	molecule	NOUN
biomedich-274	317	19	docking	docking	NOUN
biomedich-274	317	20	based	base	VERB
biomedich-274	317	21	strategy	strategy	NOUN
biomedich-274	317	22	.	.	PUNCT
biomedich-274	317	23	”	"	PUNCT
biomedich-274	318	1	journal	journal	NOUN
biomedich-274	318	2	of	of	ADP
biomedich-274	318	3	ethnopharmacology	ethnopharmacology	NOUN
biomedich-274	318	4	239	239	NUM
biomedich-274	318	5	(	(	PUNCT
biomedich-274	318	6	july	july	PROPN
biomedich-274	318	7	):	):	PUNCT
biomedich-274	318	8	111909	111909	NUM
biomedich-274	318	9	.	.	PUNCT
biomedich-274	319	1	https://doi.org/10.1016/j.jep.2019.111909	https://doi.org/10.1016/j.jep.2019.111909	PROPN
biomedich-274	319	2	.	.	PUNCT
biomedich-274	320	1	yarmolinsky	yarmolinsky	PROPN
biomedich-274	320	2	,	,	PUNCT
biomedich-274	320	3	ludmila	ludmila	PROPN
biomedich-274	320	4	,	,	PUNCT
biomedich-274	320	5	mahmoud	mahmoud	PROPN
biomedich-274	320	6	huleihel	huleihel	PROPN
biomedich-274	320	7	,	,	PUNCT
biomedich-274	320	8	michele	michele	PROPN
biomedich-274	320	9	zaccai	zaccai	PROPN
biomedich-274	320	10	,	,	PUNCT
biomedich-274	320	11	and	and	CCONJ
biomedich-274	320	12	shimon	shimon	PROPN
biomedich-274	320	13	ben	ben	PROPN
biomedich-274	320	14	-	-	PUNCT
biomedich-274	320	15	shabat	shabat	PROPN
biomedich-274	320	16	.	.	PUNCT
biomedich-274	320	17	2012	2012	NUM
biomedich-274	320	18	.	.	PUNCT
biomedich-274	321	1	“	"	PUNCT
biomedich-274	321	2	potent	potent	ADJ
biomedich-274	321	3	antiviral	antiviral	ADJ
biomedich-274	321	4	flavone	flavone	NOUN
biomedich-274	321	5	glycosides	glycoside	NOUN
biomedich-274	321	6	from	from	ADP
biomedich-274	321	7	ficus	ficus	NOUN
biomedich-274	321	8	benjamina	benjamina	NOUN
biomedich-274	321	9	leaves	leave	NOUN
biomedich-274	321	10	.	.	PUNCT
biomedich-274	321	11	”	"	PUNCT
biomedich-274	322	1	fitoterapia	fitoterapia	PROPN
biomedich-274	322	2	83	83	NUM
biomedich-274	322	3	(	(	PUNCT
biomedich-274	322	4	2	2	NUM
biomedich-274	322	5	):	):	PUNCT
biomedich-274	322	6	362–67	362–67	NUM
biomedich-274	322	7	.	.	PUNCT
biomedich-274	323	1	https://doi.org/10.1016/j.fitote.2011.11.014	https://doi.org/10.1016/j.fitote.2011.11.014	NOUN
biomedich-274	323	2	.	.	PUNCT
biomedich-274	324	1	yuan	yuan	PROPN
biomedich-274	324	2	,	,	PUNCT
biomedich-274	324	3	li	li	PROPN
biomedich-274	324	4	,	,	PUNCT
biomedich-274	324	5	jing	jing	PROPN
biomedich-274	324	6	wang	wang	PROPN
biomedich-274	324	7	,	,	PUNCT
biomedich-274	324	8	wanqiang	wanqiang	PROPN
biomedich-274	324	9	wu	wu	PROPN
biomedich-274	324	10	,	,	PUNCT
biomedich-274	324	11	qian	qian	PROPN
biomedich-274	324	12	liu	liu	PROPN
biomedich-274	324	13	,	,	PUNCT
biomedich-274	324	14	and	and	CCONJ
biomedich-274	324	15	xuebo	xuebo	PROPN
biomedich-274	324	16	liu	liu	PROPN
biomedich-274	324	17	.	.	PROPN
biomedich-274	324	18	2016	2016	NUM
biomedich-274	324	19	.	.	PUNCT
biomedich-274	325	1	“	"	PUNCT
biomedich-274	325	2	effect	effect	NOUN
biomedich-274	325	3	of	of	ADP
biomedich-274	325	4	isoorientin	isoorientin	ADJ
biomedich-274	325	5	on	on	ADP
biomedich-274	325	6	intracellular	intracellular	ADJ
biomedich-274	325	7	antioxidant	antioxidant	ADJ
biomedich-274	325	8	defence	defence	NOUN
biomedich-274	325	9	mechanisms	mechanism	NOUN
biomedich-274	325	10	in	in	ADP
biomedich-274	325	11	hepatoma	hepatoma	NOUN
biomedich-274	325	12	and	and	CCONJ
biomedich-274	325	13	liver	liver	NOUN
biomedich-274	325	14	cell	cell	NOUN
biomedich-274	325	15	lines	line	NOUN
biomedich-274	325	16	.	.	PUNCT
biomedich-274	325	17	”	"	PUNCT
biomedich-274	326	1	biomedicine	biomedicine	NOUN
biomedich-274	326	2	&	&	CCONJ
biomedich-274	326	3	pharmacotherapy	pharmacotherapy	NOUN
biomedich-274	326	4	=	=	SYM
biomedich-274	326	5	biomedecine	biomedecine	NOUN
biomedich-274	326	6	&	&	CCONJ
biomedich-274	326	7	pharmacotherapie	pharmacotherapie	PROPN
biomedich-274	326	8	81	81	NUM
biomedich-274	326	9	(	(	PUNCT
biomedich-274	326	10	july	july	PROPN
biomedich-274	326	11	):	):	PUNCT
biomedich-274	326	12	356–62	356–62	NUM
biomedich-274	326	13	.	.	PUNCT
biomedich-274	326	14	https://doi.org/10.1016/j.biopha.2016.04.025	https://doi.org/10.1016/j.biopha.2016.04.025	NUM
biomedich-274	326	15	.	.	PUNCT