id	sid	tid	token	lemma	pos
biomedich-632	1	1	biology	biology	NOUN
biomedich-632	1	2	,	,	PUNCT
biomedich-632	1	3	medicine	medicine	NOUN
biomedich-632	1	4	,	,	PUNCT
biomedich-632	1	5	&	&	CCONJ
biomedich-632	1	6	natural	natural	ADJ
biomedich-632	1	7	product	product	NOUN
biomedich-632	1	8	chemistry	chemistry	NOUN
biomedich-632	1	9	issn	issn	VERB
biomedich-632	1	10	2089	2089	NUM
biomedich-632	1	11	-	-	SYM
biomedich-632	1	12	6514	6514	NUM
biomedich-632	1	13	(	(	PUNCT
biomedich-632	1	14	paper	paper	NOUN
biomedich-632	1	15	)	)	PUNCT
biomedich-632	1	16	volume	volume	NOUN
biomedich-632	1	17	14	14	NUM
biomedich-632	1	18	,	,	PUNCT
biomedich-632	1	19	number	number	NOUN
biomedich-632	1	20	1	1	NUM
biomedich-632	1	21	,	,	PUNCT
biomedich-632	1	22	april	april	PROPN
biomedich-632	1	23	2025	2025	NUM
biomedich-632	2	1	|	|	ADV
biomedich-632	2	2	pages	page	NOUN
biomedich-632	2	3	:	:	PUNCT
biomedich-632	2	4	43	43	NUM
biomedich-632	2	5	-	-	SYM
biomedich-632	2	6	50	50	NUM
biomedich-632	2	7	|	|	ADV
biomedich-632	2	8	doi	doi	NOUN
biomedich-632	2	9	:	:	PUNCT
biomedich-632	2	10	10.14421	10.14421	NUM
biomedich-632	2	11	/	/	SYM
biomedich-632	2	12	biomedich.2025.141.43	biomedich.2025.141.43	PROPN
biomedich-632	2	13	-	-	PUNCT
biomedich-632	2	14	50	50	NUM
biomedich-632	2	15	issn	issn	PROPN
biomedich-632	2	16	2540	2540	NUM
biomedich-632	2	17	-	-	SYM
biomedich-632	2	18	9328	9328	NUM
biomedich-632	2	19	(	(	PUNCT
biomedich-632	2	20	online	online	ADJ
biomedich-632	2	21	)	)	PUNCT
biomedich-632	2	22	correlation	correlation	NOUN
biomedich-632	2	23	of	of	ADP
biomedich-632	2	24	bmp2	bmp2	NOUN
biomedich-632	2	25	with	with	ADP
biomedich-632	2	26	degree	degree	NOUN
biomedich-632	2	27	of	of	ADP
biomedich-632	2	28	osteitisin	osteitisin	NOUN
biomedich-632	2	29	primary	primary	ADJ
biomedich-632	2	30	crs	crs	PROPN
biomedich-632	2	31	with	with	ADP
biomedich-632	2	32	and	and	CCONJ
biomedich-632	2	33	without	without	ADP
biomedich-632	2	34	nasal	nasal	ADJ
biomedich-632	2	35	polyps	polyp	NOUN
biomedich-632	2	36	edi	edi	PROPN
biomedich-632	2	37	handoko1	handoko1	PROPN
biomedich-632	2	38	,	,	PUNCT
biomedich-632	2	39	david	david	PROPN
biomedich-632	2	40	santoso2	santoso2	PROPN
biomedich-632	2	41	,	,	PUNCT
biomedich-632	2	42	iriana	iriana	PROPN
biomedich-632	2	43	maharani3	maharani3	PROPN
biomedich-632	2	44	,	,	PUNCT
biomedich-632	2	45	*	*	PROPN
biomedich-632	2	46	,	,	PUNCT
biomedich-632	2	47	yuyun	yuyun	PROPN
biomedich-632	2	48	yueniwati	yueniwati	PROPN
biomedich-632	2	49	p.w4	p.w4	PROPN
biomedich-632	2	50	,	,	PUNCT
biomedich-632	2	51	tanti	tanti	NOUN
biomedich-632	2	52	agustina5	agustina5	NOUN
biomedich-632	2	53	1,2,3department	1,2,3department	NUM
biomedich-632	2	54	of	of	ADP
biomedich-632	2	55	otorhinolaryngology	otorhinolaryngology	NOUN
biomedich-632	2	56	-	-	PUNCT
biomedich-632	2	57	head	head	NOUN
biomedich-632	2	58	and	and	CCONJ
biomedich-632	2	59	neck	neck	NOUN
biomedich-632	2	60	surgery	surgery	NOUN
biomedich-632	2	61	,	,	PUNCT
biomedich-632	2	62	faculty	faculty	NOUN
biomedich-632	2	63	of	of	ADP
biomedich-632	2	64	medicine	medicine	NOUN
biomedich-632	2	65	;	;	PUNCT
biomedich-632	2	66	4radiology	4radiology	PROPN
biomedich-632	2	67	department	department	NOUN
biomedich-632	2	68	,	,	PUNCT
biomedich-632	2	69	faculty	faculty	NOUN
biomedich-632	2	70	of	of	ADP
biomedich-632	2	71	medicine	medicine	NOUN
biomedich-632	2	72	,	,	PUNCT
biomedich-632	2	73	universitas	universita	NOUN
biomedich-632	2	74	brawijaya	brawijaya	NOUN
biomedich-632	2	75	/	/	SYM
biomedich-632	2	76	dr	dr	PROPN
biomedich-632	2	77	.	.	PROPN
biomedich-632	2	78	saiful	saiful	PROPN
biomedich-632	2	79	anwar	anwar	PROPN
biomedich-632	2	80	general	general	PROPN
biomedich-632	2	81	hospital	hospital	PROPN
biomedich-632	2	82	,	,	PUNCT
biomedich-632	2	83	malang	malang	PROPN
biomedich-632	2	84	,	,	PUNCT
biomedich-632	2	85	indonesia	indonesia	PROPN
biomedich-632	2	86	.	.	PUNCT
biomedich-632	3	1	5biology	5biology	NUM
biomedich-632	3	2	department	department	NOUN
biomedich-632	3	3	,	,	PUNCT
biomedich-632	3	4	faculty	faculty	NOUN
biomedich-632	3	5	of	of	ADP
biomedich-632	3	6	biology	biology	NOUN
biomedich-632	3	7	,	,	PUNCT
biomedich-632	3	8	universitas	universita	NOUN
biomedich-632	3	9	gadjah	gadjah	PROPN
biomedich-632	3	10	mada	mada	PROPN
biomedich-632	3	11	,	,	PUNCT
biomedich-632	3	12	sleman	sleman	NOUN
biomedich-632	3	13	,	,	PUNCT
biomedich-632	3	14	yogyakarta	yogyakarta	PROPN
biomedich-632	3	15	,	,	PUNCT
biomedich-632	3	16	indonesia	indonesia	PROPN
biomedich-632	3	17	.	.	PUNCT
biomedich-632	4	1	corresponding	correspond	VERB
biomedich-632	4	2	author	author	NOUN
biomedich-632	4	3	*	*	PROPN
biomedich-632	4	4	iriana_maharani@ub.ac.id	iriana_maharani@ub.ac.id	NOUN
biomedich-632	4	5	manuscript	manuscript	NOUN
biomedich-632	4	6	received	receive	VERB
biomedich-632	4	7	:	:	PUNCT
biomedich-632	4	8	07	07	NUM
biomedich-632	4	9	november	november	PROPN
biomedich-632	4	10	,	,	PUNCT
biomedich-632	4	11	2024	2024	NUM
biomedich-632	4	12	.	.	PUNCT
biomedich-632	5	1	revision	revision	NOUN
biomedich-632	5	2	accepted	accept	VERB
biomedich-632	5	3	:	:	PUNCT
biomedich-632	5	4	17	17	NUM
biomedich-632	5	5	february	february	NOUN
biomedich-632	5	6	,	,	PUNCT
biomedich-632	5	7	2025	2025	NUM
biomedich-632	5	8	.	.	PUNCT
biomedich-632	6	1	published	publish	VERB
biomedich-632	6	2	:	:	PUNCT
biomedich-632	6	3	28	28	NUM
biomedich-632	6	4	february	february	PROPN
biomedich-632	6	5	,	,	PUNCT
biomedich-632	6	6	2025	2025	NUM
biomedich-632	6	7	.	.	PUNCT
biomedich-632	7	1	abstract	abstract	ADJ
biomedich-632	7	2	chronic	chronic	ADJ
biomedich-632	7	3	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	7	4	(	(	PUNCT
biomedich-632	7	5	crs	crs	PROPN
biomedich-632	7	6	)	)	PUNCT
biomedich-632	7	7	is	be	AUX
biomedich-632	7	8	an	an	DET
biomedich-632	7	9	inflammation	inflammation	NOUN
biomedich-632	7	10	of	of	ADP
biomedich-632	7	11	the	the	DET
biomedich-632	7	12	nasal	nasal	ADJ
biomedich-632	7	13	mucosa	mucosa	PROPN
biomedich-632	7	14	and	and	CCONJ
biomedich-632	7	15	paranasal	paranasal	ADJ
biomedich-632	7	16	sinuses	sinus	NOUN
biomedich-632	7	17	,	,	PUNCT
biomedich-632	7	18	persisting	persist	VERB
biomedich-632	7	19	for	for	ADP
biomedich-632	7	20	over	over	ADP
biomedich-632	7	21	12	12	NUM
biomedich-632	7	22	weeks	week	NOUN
biomedich-632	7	23	.	.	PUNCT
biomedich-632	8	1	crs	crs	PROPN
biomedich-632	8	2	involves	involve	VERB
biomedich-632	8	3	a	a	DET
biomedich-632	8	4	remodeling	remodeling	NOUN
biomedich-632	8	5	process	process	NOUN
biomedich-632	8	6	and	and	CCONJ
biomedich-632	8	7	opacification	opacification	NOUN
biomedich-632	8	8	known	know	VERB
biomedich-632	8	9	as	as	ADP
biomedich-632	8	10	osteitis	osteitis	NOUN
biomedich-632	8	11	,	,	PUNCT
biomedich-632	8	12	resulting	result	VERB
biomedich-632	8	13	from	from	ADP
biomedich-632	8	14	type	type	NOUN
biomedich-632	8	15	2	2	NUM
biomedich-632	8	16	and	and	CCONJ
biomedich-632	8	17	non	non	ADJ
biomedich-632	8	18	-	-	ADJ
biomedich-632	8	19	type	type	ADJ
biomedich-632	8	20	two	two	NUM
biomedich-632	8	21	inflammation	inflammation	NOUN
biomedich-632	8	22	.	.	PUNCT
biomedich-632	9	1	osteitis	osteitis	NOUN
biomedich-632	9	2	severity	severity	NOUN
biomedich-632	9	3	is	be	AUX
biomedich-632	9	4	assessed	assess	VERB
biomedich-632	9	5	using	use	VERB
biomedich-632	9	6	ct	ct	PROPN
biomedich-632	9	7	scans	scan	NOUN
biomedich-632	9	8	and	and	CCONJ
biomedich-632	9	9	the	the	DET
biomedich-632	9	10	global	global	ADJ
biomedich-632	9	11	osteitis	osteitis	NOUN
biomedich-632	9	12	scoring	scoring	NOUN
biomedich-632	9	13	scale	scale	NOUN
biomedich-632	9	14	(	(	PUNCT
biomedich-632	9	15	goss	goss	PROPN
biomedich-632	9	16	)	)	PUNCT
biomedich-632	9	17	.	.	PUNCT
biomedich-632	10	1	bone	bone	NOUN
biomedich-632	10	2	morphogenetic	morphogenetic	ADJ
biomedich-632	10	3	protein-2	protein-2	PROPN
biomedich-632	10	4	(	(	PUNCT
biomedich-632	10	5	bmp-2	bmp-2	NOUN
biomedich-632	10	6	)	)	PUNCT
biomedich-632	10	7	is	be	AUX
biomedich-632	10	8	crucial	crucial	ADJ
biomedich-632	10	9	in	in	ADP
biomedich-632	10	10	osteogenesis	osteogenesis	NOUN
biomedich-632	10	11	and	and	CCONJ
biomedich-632	10	12	bone	bone	NOUN
biomedich-632	10	13	remodeling	remodeling	NOUN
biomedich-632	10	14	.	.	PUNCT
biomedich-632	11	1	however	however	ADV
biomedich-632	11	2	,	,	PUNCT
biomedich-632	11	3	no	no	DET
biomedich-632	11	4	research	research	NOUN
biomedich-632	11	5	has	have	AUX
biomedich-632	11	6	shown	show	VERB
biomedich-632	11	7	a	a	DET
biomedich-632	11	8	relationship	relationship	NOUN
biomedich-632	11	9	between	between	ADP
biomedich-632	11	10	bmp-2	bmp-2	NOUN
biomedich-632	11	11	concentration	concentration	NOUN
biomedich-632	11	12	and	and	CCONJ
biomedich-632	11	13	osteitis	osteitis	NOUN
biomedich-632	11	14	degree	degree	NOUN
biomedich-632	11	15	,	,	PUNCT
biomedich-632	11	16	as	as	SCONJ
biomedich-632	11	17	measured	measure	VERB
biomedich-632	11	18	by	by	ADP
biomedich-632	11	19	goss	goss	PROPN
biomedich-632	11	20	,	,	PUNCT
biomedich-632	11	21	in	in	ADP
biomedich-632	11	22	crs	crs	NOUN
biomedich-632	11	23	patients	patient	NOUN
biomedich-632	11	24	with	with	ADP
biomedich-632	11	25	or	or	CCONJ
biomedich-632	11	26	without	without	ADP
biomedich-632	11	27	nasal	nasal	ADJ
biomedich-632	11	28	polyps	polyp	NOUN
biomedich-632	11	29	.	.	PUNCT
biomedich-632	12	1	the	the	DET
biomedich-632	12	2	objective	objective	NOUN
biomedich-632	12	3	of	of	ADP
biomedich-632	12	4	this	this	DET
biomedich-632	12	5	study	study	NOUN
biomedich-632	12	6	is	be	AUX
biomedich-632	12	7	to	to	PART
biomedich-632	12	8	analyze	analyze	VERB
biomedich-632	12	9	the	the	DET
biomedich-632	12	10	relationship	relationship	NOUN
biomedich-632	12	11	between	between	ADP
biomedich-632	12	12	bmp-2	bmp-2	NUM
biomedich-632	12	13	concentration	concentration	NOUN
biomedich-632	12	14	and	and	CCONJ
biomedich-632	12	15	osteitis	osteitis	NOUN
biomedich-632	12	16	degree	degree	NOUN
biomedich-632	12	17	measure	measure	NOUN
biomedich-632	12	18	with	with	ADP
biomedich-632	12	19	goss	goss	PROPN
biomedich-632	12	20	in	in	ADP
biomedich-632	12	21	primary	primary	ADJ
biomedich-632	12	22	crs	crs	PROPN
biomedich-632	12	23	.	.	PUNCT
biomedich-632	13	1	a	a	DET
biomedich-632	13	2	cross	cross	ADJ
biomedich-632	13	3	-	-	ADJ
biomedich-632	13	4	sectional	sectional	ADJ
biomedich-632	13	5	analytic	analytic	ADJ
biomedich-632	13	6	observational	observational	ADJ
biomedich-632	13	7	study	study	NOUN
biomedich-632	13	8	was	be	AUX
biomedich-632	13	9	conducted	conduct	VERB
biomedich-632	13	10	using	use	VERB
biomedich-632	13	11	primary	primary	ADJ
biomedich-632	13	12	rsk	rsk	PROPN
biomedich-632	13	13	as	as	ADP
biomedich-632	13	14	the	the	DET
biomedich-632	13	15	study	study	NOUN
biomedich-632	13	16	population	population	NOUN
biomedich-632	13	17	.	.	PUNCT
biomedich-632	14	1	bmp-2	bmp-2	X
biomedich-632	14	2	concentration	concentration	NOUN
biomedich-632	14	3	,	,	PUNCT
biomedich-632	14	4	a	a	DET
biomedich-632	14	5	marker	marker	NOUN
biomedich-632	14	6	for	for	ADP
biomedich-632	14	7	bone	bone	NOUN
biomedich-632	14	8	remodeling	remodeling	NOUN
biomedich-632	14	9	,	,	PUNCT
biomedich-632	14	10	used	use	VERB
biomedich-632	14	11	elisa	elisa	NOUN
biomedich-632	14	12	.	.	PUNCT
biomedich-632	15	1	the	the	DET
biomedich-632	15	2	osteitis	osteitis	NOUN
biomedich-632	15	3	of	of	ADP
biomedich-632	15	4	the	the	DET
biomedich-632	15	5	paranasal	paranasal	ADJ
biomedich-632	15	6	sinus	sinus	NOUN
biomedich-632	15	7	walls	wall	NOUN
biomedich-632	15	8	was	be	AUX
biomedich-632	15	9	assessed	assess	VERB
biomedich-632	15	10	with	with	ADP
biomedich-632	15	11	a	a	DET
biomedich-632	15	12	ct	ct	NOUN
biomedich-632	15	13	scan	scan	NOUN
biomedich-632	15	14	and	and	CCONJ
biomedich-632	15	15	quantified	quantify	VERB
biomedich-632	15	16	using	use	VERB
biomedich-632	15	17	the	the	DET
biomedich-632	15	18	goss	goss	PROPN
biomedich-632	15	19	method	method	NOUN
biomedich-632	15	20	.	.	PUNCT
biomedich-632	16	1	the	the	DET
biomedich-632	16	2	study	study	NOUN
biomedich-632	16	3	included	include	VERB
biomedich-632	16	4	44	44	NUM
biomedich-632	16	5	patients	patient	NOUN
biomedich-632	16	6	,	,	PUNCT
biomedich-632	16	7	with	with	ADP
biomedich-632	16	8	8	8	NUM
biomedich-632	16	9	of	of	ADP
biomedich-632	16	10	them	they	PRON
biomedich-632	16	11	serving	serve	VERB
biomedich-632	16	12	as	as	ADP
biomedich-632	16	13	the	the	DET
biomedich-632	16	14	control	control	NOUN
biomedich-632	16	15	group	group	NOUN
biomedich-632	16	16	.	.	PUNCT
biomedich-632	17	1	it	it	PRON
biomedich-632	17	2	was	be	AUX
biomedich-632	17	3	found	find	VERB
biomedich-632	17	4	that	that	SCONJ
biomedich-632	17	5	bmp-2	bmp-2	ADJ
biomedich-632	17	6	concentration	concentration	NOUN
biomedich-632	17	7	(	(	PUNCT
biomedich-632	17	8	ng	ng	NOUN
biomedich-632	17	9	/	/	SYM
biomedich-632	17	10	ml	ml	PROPN
biomedich-632	17	11	)	)	PUNCT
biomedich-632	17	12	had	have	VERB
biomedich-632	17	13	a	a	DET
biomedich-632	17	14	linear	linear	ADJ
biomedich-632	17	15	relationship	relationship	NOUN
biomedich-632	17	16	with	with	ADP
biomedich-632	17	17	the	the	DET
biomedich-632	17	18	goss	goss	PROPN
biomedich-632	17	19	degree	degree	NOUN
biomedich-632	17	20	in	in	ADP
biomedich-632	17	21	patients	patient	NOUN
biomedich-632	17	22	with	with	ADP
biomedich-632	17	23	crs	crs	PROPN
biomedich-632	17	24	,	,	PUNCT
biomedich-632	17	25	showing	show	VERB
biomedich-632	17	26	a	a	DET
biomedich-632	17	27	correlation	correlation	NOUN
biomedich-632	17	28	of	of	ADP
biomedich-632	17	29	0.583	0.583	NUM
biomedich-632	17	30	(	(	PUNCT
biomedich-632	17	31	deviation	deviation	NOUN
biomedich-632	17	32	>	>	NOUN
biomedich-632	17	33	0.05	0.05	NUM
biomedich-632	17	34	)	)	PUNCT
biomedich-632	17	35	.	.	PUNCT
biomedich-632	18	1	further	further	ADJ
biomedich-632	18	2	analysis	analysis	NOUN
biomedich-632	18	3	revealed	reveal	VERB
biomedich-632	18	4	a	a	DET
biomedich-632	18	5	significant	significant	ADJ
biomedich-632	18	6	correlation	correlation	NOUN
biomedich-632	18	7	between	between	ADP
biomedich-632	18	8	bmp-2	bmp-2	NUM
biomedich-632	18	9	concentration	concentration	NOUN
biomedich-632	18	10	and	and	CCONJ
biomedich-632	18	11	goss	goss	PROPN
biomedich-632	18	12	,	,	PUNCT
biomedich-632	18	13	with	with	ADP
biomedich-632	18	14	a	a	DET
biomedich-632	18	15	coefficient	coefficient	NOUN
biomedich-632	18	16	of	of	ADP
biomedich-632	18	17	0.857	0.857	NUM
biomedich-632	18	18	(	(	PUNCT
biomedich-632	18	19	considered	consider	VERB
biomedich-632	18	20	very	very	ADV
biomedich-632	18	21	significant	significant	ADJ
biomedich-632	18	22	,	,	PUNCT
biomedich-632	18	23	in	in	ADP
biomedich-632	18	24	the	the	DET
biomedich-632	18	25	range	range	NOUN
biomedich-632	18	26	of	of	ADP
biomedich-632	18	27	0.76	0.76	NUM
biomedich-632	18	28	-	-	PUNCT
biomedich-632	18	29	0.99	0.99	NUM
biomedich-632	18	30	)	)	PUNCT
biomedich-632	18	31	.	.	PUNCT
biomedich-632	19	1	this	this	DET
biomedich-632	19	2	strong	strong	ADJ
biomedich-632	19	3	correlation	correlation	NOUN
biomedich-632	19	4	indicates	indicate	VERB
biomedich-632	19	5	that	that	SCONJ
biomedich-632	19	6	as	as	SCONJ
biomedich-632	19	7	bmp-2	bmp-2	ADJ
biomedich-632	19	8	concentration	concentration	NOUN
biomedich-632	19	9	strongly	strongly	ADV
biomedich-632	19	10	correlates	correlate	VERB
biomedich-632	19	11	with	with	ADP
biomedich-632	19	12	the	the	DET
biomedich-632	19	13	occurance	occurance	NOUN
biomedich-632	19	14	of	of	ADP
biomedich-632	19	15	osteitis	osteitis	PROPN
biomedich-632	19	16	,	,	PUNCT
biomedich-632	19	17	which	which	PRON
biomedich-632	19	18	were	be	AUX
biomedich-632	19	19	measured	measure	VERB
biomedich-632	19	20	by	by	ADP
biomedich-632	19	21	goss	goss	PROPN
biomedich-632	19	22	.	.	PUNCT
biomedich-632	20	1	bmp-2	bmp-2	NUM
biomedich-632	20	2	,	,	PUNCT
biomedich-632	20	3	as	as	ADP
biomedich-632	20	4	a	a	DET
biomedich-632	20	5	marker	marker	NOUN
biomedich-632	20	6	for	for	ADP
biomedich-632	20	7	osteitis	osteitis	NOUN
biomedich-632	20	8	in	in	ADP
biomedich-632	20	9	crs	crs	PROPN
biomedich-632	20	10	,	,	PUNCT
biomedich-632	20	11	shows	show	VERB
biomedich-632	20	12	a	a	DET
biomedich-632	20	13	significant	significant	ADJ
biomedich-632	20	14	and	and	CCONJ
biomedich-632	20	15	linear	linear	ADJ
biomedich-632	20	16	correlation	correlation	NOUN
biomedich-632	20	17	with	with	ADP
biomedich-632	20	18	the	the	DET
biomedich-632	20	19	severity	severity	NOUN
biomedich-632	20	20	degree	degree	NOUN
biomedich-632	20	21	of	of	ADP
biomedich-632	20	22	osteitis	osteitis	NOUN
biomedich-632	20	23	measured	measure	VERB
biomedich-632	20	24	by	by	ADP
biomedich-632	20	25	goss	goss	PROPN
biomedich-632	20	26	.	.	PUNCT
biomedich-632	21	1	keywords	keyword	NOUN
biomedich-632	21	2	:	:	PUNCT
biomedich-632	21	3	bmp-2	bmp-2	ADJ
biomedich-632	21	4	concentration	concentration	NOUN
biomedich-632	21	5	;	;	PUNCT
biomedich-632	21	6	chronic	chronic	ADJ
biomedich-632	21	7	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	21	8	;	;	PUNCT
biomedich-632	21	9	global	global	ADJ
biomedich-632	21	10	osteitis	osteitis	NOUN
biomedich-632	21	11	scoring	scoring	NOUN
biomedich-632	21	12	scale	scale	NOUN
biomedich-632	21	13	;	;	PUNCT
biomedich-632	21	14	osteitis	osteitis	NOUN
biomedich-632	21	15	.	.	PUNCT
biomedich-632	22	1	introduction	introduction	NOUN
biomedich-632	22	2	the	the	DET
biomedich-632	22	3	paranasal	paranasal	ADJ
biomedich-632	22	4	sinuses	sinus	NOUN
biomedich-632	22	5	are	be	AUX
biomedich-632	22	6	air	air	NOUN
biomedich-632	22	7	-	-	PUNCT
biomedich-632	22	8	filled	fill	VERB
biomedich-632	22	9	cavities	cavity	NOUN
biomedich-632	22	10	located	locate	VERB
biomedich-632	22	11	within	within	ADP
biomedich-632	22	12	certain	certain	ADJ
biomedich-632	22	13	bones	bone	NOUN
biomedich-632	22	14	of	of	ADP
biomedich-632	22	15	the	the	DET
biomedich-632	22	16	skull	skull	NOUN
biomedich-632	22	17	.	.	PUNCT
biomedich-632	23	1	each	each	DET
biomedich-632	23	2	side	side	NOUN
biomedich-632	23	3	of	of	ADP
biomedich-632	23	4	the	the	DET
biomedich-632	23	5	skull	skull	NOUN
biomedich-632	23	6	contains	contain	VERB
biomedich-632	23	7	four	four	NUM
biomedich-632	23	8	paranasal	paranasal	ADJ
biomedich-632	23	9	sinuses	sinus	NOUN
biomedich-632	23	10	:	:	PUNCT
biomedich-632	23	11	the	the	DET
biomedich-632	23	12	frontal	frontal	ADJ
biomedich-632	23	13	,	,	PUNCT
biomedich-632	23	14	maxillary	maxillary	NOUN
biomedich-632	23	15	,	,	PUNCT
biomedich-632	23	16	ethmoid	ethmoid	NOUN
biomedich-632	23	17	,	,	PUNCT
biomedich-632	23	18	and	and	CCONJ
biomedich-632	23	19	sphenoid	sphenoid	NOUN
biomedich-632	23	20	sinuses	sinus	NOUN
biomedich-632	23	21	.	.	PUNCT
biomedich-632	24	1	inflammation	inflammation	NOUN
biomedich-632	24	2	of	of	ADP
biomedich-632	24	3	the	the	DET
biomedich-632	24	4	nasal	nasal	ADJ
biomedich-632	24	5	mucosa	mucosa	PROPN
biomedich-632	24	6	and	and	CCONJ
biomedich-632	24	7	paranasal	paranasal	ADJ
biomedich-632	24	8	sinuses	sinus	NOUN
biomedich-632	24	9	is	be	AUX
biomedich-632	24	10	known	know	VERB
biomedich-632	24	11	as	as	ADP
biomedich-632	24	12	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	24	13	.	.	PUNCT
biomedich-632	25	1	when	when	SCONJ
biomedich-632	25	2	symptoms	symptom	NOUN
biomedich-632	25	3	persist	persist	VERB
biomedich-632	25	4	for	for	ADP
biomedich-632	25	5	more	more	ADJ
biomedich-632	25	6	than	than	ADP
biomedich-632	25	7	12	12	NUM
biomedich-632	25	8	weeks	week	NOUN
biomedich-632	25	9	without	without	ADP
biomedich-632	25	10	complete	complete	ADJ
biomedich-632	25	11	resolution	resolution	NOUN
biomedich-632	25	12	,	,	PUNCT
biomedich-632	25	13	the	the	DET
biomedich-632	25	14	condition	condition	NOUN
biomedich-632	25	15	is	be	AUX
biomedich-632	25	16	classified	classify	VERB
biomedich-632	25	17	as	as	ADP
biomedich-632	25	18	chronic	chronic	ADJ
biomedich-632	25	19	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	25	20	(	(	PUNCT
biomedich-632	25	21	crs	crs	PROPN
biomedich-632	25	22	)	)	PUNCT
biomedich-632	25	23	(	(	PUNCT
biomedich-632	25	24	dhingra	dhingra	NOUN
biomedich-632	25	25	,	,	PUNCT
biomedich-632	25	26	2021	2021	NUM
biomedich-632	25	27	;	;	PUNCT
biomedich-632	25	28	brandi	brandi	PROPN
biomedich-632	25	29	,	,	PUNCT
biomedich-632	25	30	2019	2019	NUM
biomedich-632	25	31	)	)	PUNCT
biomedich-632	25	32	.	.	PUNCT
biomedich-632	26	1	rhinosinusitis	rhinosinusitis	PROPN
biomedich-632	26	2	is	be	AUX
biomedich-632	26	3	a	a	DET
biomedich-632	26	4	significant	significant	ADJ
biomedich-632	26	5	health	health	NOUN
biomedich-632	26	6	issue	issue	NOUN
biomedich-632	26	7	worldwide	worldwide	ADV
biomedich-632	26	8	.	.	PUNCT
biomedich-632	27	1	in	in	ADP
biomedich-632	27	2	the	the	DET
biomedich-632	27	3	united	united	PROPN
biomedich-632	27	4	states	states	PROPN
biomedich-632	27	5	,	,	PUNCT
biomedich-632	27	6	crs	crs	PROPN
biomedich-632	27	7	is	be	AUX
biomedich-632	27	8	one	one	NUM
biomedich-632	27	9	of	of	ADP
biomedich-632	27	10	the	the	DET
biomedich-632	27	11	most	most	ADV
biomedich-632	27	12	common	common	ADJ
biomedich-632	27	13	reasons	reason	NOUN
biomedich-632	27	14	patients	patient	NOUN
biomedich-632	27	15	seek	seek	VERB
biomedich-632	27	16	medical	medical	ADJ
biomedich-632	27	17	attention	attention	NOUN
biomedich-632	27	18	.	.	PUNCT
biomedich-632	28	1	around	around	ADV
biomedich-632	28	2	0.5	0.5	NUM
biomedich-632	28	3	%	%	NOUN
biomedich-632	28	4	of	of	ADP
biomedich-632	28	5	acute	acute	ADJ
biomedich-632	28	6	respiratory	respiratory	ADJ
biomedich-632	28	7	infections	infection	NOUN
biomedich-632	28	8	(	(	PUNCT
biomedich-632	28	9	aris	aris	PROPN
biomedich-632	28	10	)	)	PUNCT
biomedich-632	28	11	caused	cause	VERB
biomedich-632	28	12	by	by	ADP
biomedich-632	28	13	viruses	virus	NOUN
biomedich-632	28	14	in	in	ADP
biomedich-632	28	15	the	the	DET
biomedich-632	28	16	u.s	u.s	PROPN
biomedich-632	28	17	.	.	PROPN
biomedich-632	28	18	progress	progress	NOUN
biomedich-632	28	19	to	to	ADP
biomedich-632	28	20	rhinosinusitis	rhinosinusitis	PROPN
biomedich-632	28	21	.	.	PUNCT
biomedich-632	29	1	crs	crs	PROPN
biomedich-632	29	2	impacts	impact	NOUN
biomedich-632	29	3	around	around	ADP
biomedich-632	29	4	31	31	NUM
biomedich-632	29	5	million	million	NUM
biomedich-632	29	6	individuals	individual	NOUN
biomedich-632	29	7	in	in	ADP
biomedich-632	29	8	the	the	DET
biomedich-632	29	9	united	united	PROPN
biomedich-632	29	10	states	states	PROPN
biomedich-632	29	11	,	,	PUNCT
biomedich-632	29	12	constituting	constitute	VERB
biomedich-632	29	13	about	about	ADV
biomedich-632	29	14	5	5	NUM
biomedich-632	29	15	%	%	NOUN
biomedich-632	29	16	to	to	PART
biomedich-632	29	17	12	12	NUM
biomedich-632	29	18	%	%	NOUN
biomedich-632	29	19	of	of	ADP
biomedich-632	29	20	the	the	DET
biomedich-632	29	21	population	population	NOUN
biomedich-632	29	22	,	,	PUNCT
biomedich-632	29	23	making	make	VERB
biomedich-632	29	24	it	it	PRON
biomedich-632	29	25	a	a	DET
biomedich-632	29	26	significant	significant	ADJ
biomedich-632	29	27	global	global	ADJ
biomedich-632	29	28	health	health	NOUN
biomedich-632	29	29	issue	issue	NOUN
biomedich-632	29	30	(	(	PUNCT
biomedich-632	29	31	amanda	amanda	PROPN
biomedich-632	29	32	s.	s.	PROPN
biomedich-632	29	33	battisti	battisti	PROPN
biomedich-632	29	34	et	et	PROPN
biomedich-632	29	35	al	al	PROPN
biomedich-632	29	36	.	.	PROPN
biomedich-632	29	37	,	,	PUNCT
biomedich-632	29	38	2020	2020	NUM
biomedich-632	29	39	;	;	PUNCT
biomedich-632	29	40	russell	russell	PROPN
biomedich-632	29	41	a.	a.	PROPN
biomedich-632	29	42	faust	faust	PROPN
biomedich-632	29	43	.	.	PUNCT
biomedich-632	30	1	2010	2010	NUM
biomedich-632	30	2	.	.	PUNCT
biomedich-632	31	1	according	accord	VERB
biomedich-632	31	2	to	to	ADP
biomedich-632	31	3	the	the	DET
biomedich-632	31	4	european	european	ADJ
biomedich-632	31	5	position	position	NOUN
biomedich-632	31	6	paper	paper	NOUN
biomedich-632	31	7	on	on	ADP
biomedich-632	31	8	rhinosinusitis	rhinosinusitis	PROPN
biomedich-632	31	9	and	and	CCONJ
biomedich-632	31	10	nasal	nasal	ADJ
biomedich-632	31	11	polyps	polyp	NOUN
biomedich-632	31	12	(	(	PUNCT
biomedich-632	31	13	epos	epos	PROPN
biomedich-632	31	14	)	)	PUNCT
biomedich-632	31	15	2012	2012	NUM
biomedich-632	31	16	,	,	PUNCT
biomedich-632	31	17	the	the	DET
biomedich-632	31	18	prevalence	prevalence	NOUN
biomedich-632	31	19	of	of	ADP
biomedich-632	31	20	crs	crs	PROPN
biomedich-632	31	21	varies	vary	VERB
biomedich-632	31	22	globally	globally	ADV
biomedich-632	31	23	:	:	PUNCT
biomedich-632	31	24	5.5	5.5	NUM
biomedich-632	31	25	%	%	NOUN
biomedich-632	31	26	in	in	ADP
biomedich-632	31	27	brazil	brazil	PROPN
biomedich-632	31	28	,	,	PUNCT
biomedich-632	31	29	8	8	NUM
biomedich-632	31	30	%	%	NOUN
biomedich-632	31	31	in	in	ADP
biomedich-632	31	32	china	china	PROPN
biomedich-632	31	33	,	,	PUNCT
biomedich-632	31	34	11	11	NUM
biomedich-632	31	35	%	%	NOUN
biomedich-632	31	36	in	in	ADP
biomedich-632	31	37	europe	europe	PROPN
biomedich-632	31	38	and	and	CCONJ
biomedich-632	31	39	korea	korea	PROPN
biomedich-632	31	40	,	,	PUNCT
biomedich-632	31	41	and	and	CCONJ
biomedich-632	31	42	12	12	NUM
biomedich-632	31	43	%	%	NOUN
biomedich-632	31	44	in	in	ADP
biomedich-632	31	45	the	the	DET
biomedich-632	31	46	u.s	u.s	PROPN
biomedich-632	31	47	(	(	PUNCT
biomedich-632	31	48	fokkens	fokkens	PROPN
biomedich-632	31	49	et	et	PROPN
biomedich-632	31	50	al	al	PROPN
biomedich-632	31	51	.	.	PROPN
biomedich-632	31	52	,	,	PUNCT
biomedich-632	31	53	2012	2012	NUM
biomedich-632	31	54	)	)	PUNCT
biomedich-632	31	55	.	.	PUNCT
biomedich-632	32	1	data	datum	NOUN
biomedich-632	32	2	from	from	ADP
biomedich-632	32	3	the	the	DET
biomedich-632	32	4	indonesian	indonesian	PROPN
biomedich-632	32	5	ministry	ministry	PROPN
biomedich-632	32	6	of	of	ADP
biomedich-632	32	7	health	health	PROPN
biomedich-632	32	8	(	(	PUNCT
biomedich-632	32	9	depkes	depke	NOUN
biomedich-632	32	10	ri	ri	PROPN
biomedich-632	32	11	)	)	PUNCT
biomedich-632	32	12	in	in	ADP
biomedich-632	32	13	2003	2003	NUM
biomedich-632	32	14	showed	show	VERB
biomedich-632	32	15	that	that	SCONJ
biomedich-632	32	16	nasal	nasal	NOUN
biomedich-632	32	17	and	and	CCONJ
biomedich-632	32	18	sinus	sinus	NOUN
biomedich-632	32	19	diseases	disease	NOUN
biomedich-632	32	20	ranked	rank	VERB
biomedich-632	32	21	25th	25th	NOUN
biomedich-632	32	22	among	among	ADP
biomedich-632	32	23	the	the	DET
biomedich-632	32	24	top	top	ADJ
biomedich-632	32	25	50	50	NUM
biomedich-632	32	26	diseases	disease	NOUN
biomedich-632	32	27	in	in	ADP
biomedich-632	32	28	indonesia	indonesia	PROPN
biomedich-632	32	29	,	,	PUNCT
biomedich-632	32	30	with	with	ADP
biomedich-632	32	31	102,817	102,817	NUM
biomedich-632	32	32	outpatient	outpatient	NOUN
biomedich-632	32	33	cases	case	NOUN
biomedich-632	32	34	.	.	PUNCT
biomedich-632	33	1	at	at	ADP
biomedich-632	33	2	dr	dr	PROPN
biomedich-632	33	3	.	.	PROPN
biomedich-632	33	4	saiful	saiful	PROPN
biomedich-632	33	5	anwar	anwar	PROPN
biomedich-632	33	6	hospital	hospital	PROPN
biomedich-632	33	7	,	,	PUNCT
biomedich-632	33	8	annual	annual	ADJ
biomedich-632	33	9	reports	report	NOUN
biomedich-632	33	10	from	from	ADP
biomedich-632	33	11	the	the	DET
biomedich-632	33	12	ent	ent	PROPN
biomedich-632	33	13	clinic	clinic	NOUN
biomedich-632	33	14	in	in	ADP
biomedich-632	33	15	2021	2021	NUM
biomedich-632	33	16	indicated	indicate	VERB
biomedich-632	33	17	that	that	SCONJ
biomedich-632	33	18	crs	crs	PROPN
biomedich-632	33	19	cases	case	NOUN
biomedich-632	33	20	accounted	account	VERB
biomedich-632	33	21	for	for	ADP
biomedich-632	33	22	29	29	NUM
biomedich-632	33	23	%	%	NOUN
biomedich-632	33	24	of	of	ADP
biomedich-632	33	25	all	all	DET
biomedich-632	33	26	rhinology	rhinology	NOUN
biomedich-632	33	27	patients	patient	NOUN
biomedich-632	33	28	.	.	PUNCT
biomedich-632	34	1	some	some	DET
biomedich-632	34	2	patients	patient	NOUN
biomedich-632	34	3	with	with	ADP
biomedich-632	34	4	crs	crs	PROPN
biomedich-632	34	5	also	also	ADV
biomedich-632	34	6	exhibit	exhibit	VERB
biomedich-632	34	7	inflammatory	inflammatory	ADJ
biomedich-632	34	8	hyperplasia	hyperplasia	NOUN
biomedich-632	34	9	in	in	ADP
biomedich-632	34	10	the	the	DET
biomedich-632	34	11	nasal	nasal	ADJ
biomedich-632	34	12	cavity	cavity	NOUN
biomedich-632	34	13	.	.	PUNCT
biomedich-632	35	1	research	research	NOUN
biomedich-632	35	2	in	in	ADP
biomedich-632	35	3	korea	korea	PROPN
biomedich-632	35	4	found	find	VERB
biomedich-632	35	5	that	that	SCONJ
biomedich-632	35	6	the	the	DET
biomedich-632	35	7	prevalence	prevalence	NOUN
biomedich-632	35	8	of	of	ADP
biomedich-632	35	9	crs	crs	PROPN
biomedich-632	35	10	with	with	ADP
biomedich-632	35	11	nasal	nasal	PROPN
biomedich-632	35	12	polyps	polyp	NOUN
biomedich-632	35	13	is	be	AUX
biomedich-632	35	14	2.7	2.7	NUM
biomedich-632	35	15	%	%	NOUN
biomedich-632	35	16	among	among	ADP
biomedich-632	35	17	adults	adult	NOUN
biomedich-632	35	18	,	,	PUNCT
biomedich-632	35	19	with	with	ADP
biomedich-632	35	20	an	an	DET
biomedich-632	35	21	incidence	incidence	NOUN
biomedich-632	35	22	of	of	ADP
biomedich-632	35	23	0.63%-0.83	0.63%-0.83	NOUN
biomedich-632	35	24	%	%	NOUN
biomedich-632	35	25	in	in	ADP
biomedich-632	35	26	the	the	DET
biomedich-632	35	27	general	general	ADJ
biomedich-632	35	28	population	population	NOUN
biomedich-632	35	29	(	(	PUNCT
biomedich-632	35	30	soepardi	soepardi	PROPN
biomedich-632	35	31	&	&	CCONJ
biomedich-632	35	32	iskandar	iskandar	PROPN
biomedich-632	35	33	,	,	PUNCT
biomedich-632	35	34	2001	2001	NUM
biomedich-632	35	35	)	)	PUNCT
biomedich-632	35	36	.	.	PUNCT
biomedich-632	36	1	epos	epos	PROPN
biomedich-632	36	2	2020	2020	NUM
biomedich-632	36	3	categorizes	categorize	VERB
biomedich-632	36	4	crs	crs	PROPN
biomedich-632	36	5	into	into	ADP
biomedich-632	36	6	primary	primary	ADJ
biomedich-632	36	7	and	and	CCONJ
biomedich-632	36	8	secondary	secondary	ADJ
biomedich-632	36	9	types	type	NOUN
biomedich-632	36	10	.	.	PUNCT
biomedich-632	37	1	primary	primary	ADJ
biomedich-632	37	2	crs	crs	PROPN
biomedich-632	37	3	is	be	AUX
biomedich-632	37	4	further	far	ADV
biomedich-632	37	5	divided	divide	VERB
biomedich-632	37	6	based	base	VERB
biomedich-632	37	7	on	on	ADP
biomedich-632	37	8	location	location	NOUN
biomedich-632	37	9	(	(	PUNCT
biomedich-632	37	10	unilateral	unilateral	ADJ
biomedich-632	37	11	or	or	CCONJ
biomedich-632	37	12	bilateral	bilateral	ADJ
biomedich-632	37	13	)	)	PUNCT
biomedich-632	37	14	and	and	CCONJ
biomedich-632	37	15	inflammation	inflammation	NOUN
biomedich-632	37	16	type	type	NOUN
biomedich-632	37	17	(	(	PUNCT
biomedich-632	37	18	type	type	NOUN
biomedich-632	37	19	2	2	NUM
biomedich-632	37	20	or	or	CCONJ
biomedich-632	37	21	non	non	ADJ
biomedich-632	37	22	-	-	ADJ
biomedich-632	37	23	type	type	ADJ
biomedich-632	37	24	2	2	NUM
biomedich-632	37	25	)	)	PUNCT
biomedich-632	37	26	(	(	PUNCT
biomedich-632	37	27	fokkens	fokken	NOUN
biomedich-632	37	28	et	et	PROPN
biomedich-632	37	29	al	al	PROPN
biomedich-632	37	30	.	.	PROPN
biomedich-632	37	31	,	,	PUNCT
biomedich-632	37	32	2020	2020	NUM
biomedich-632	37	33	)	)	PUNCT
biomedich-632	37	34	.	.	PUNCT
biomedich-632	38	1	crs	crs	PROPN
biomedich-632	38	2	involves	involve	VERB
biomedich-632	38	3	remodeling	remodeling	NOUN
biomedich-632	38	4	and	and	CCONJ
biomedich-632	38	5	thickening	thickening	NOUN
biomedich-632	38	6	of	of	ADP
biomedich-632	38	7	the	the	DET
biomedich-632	38	8	paranasal	paranasal	ADJ
biomedich-632	38	9	sinus	sinus	NOUN
biomedich-632	38	10	bones	bone	NOUN
biomedich-632	38	11	,	,	PUNCT
biomedich-632	38	12	a	a	DET
biomedich-632	38	13	condition	condition	NOUN
biomedich-632	38	14	known	know	VERB
biomedich-632	38	15	as	as	ADP
biomedich-632	38	16	osteitis	osteitis	NOUN
biomedich-632	38	17	.	.	PUNCT
biomedich-632	39	1	this	this	PRON
biomedich-632	39	2	occurs	occur	VERB
biomedich-632	39	3	due	due	ADJ
biomedich-632	39	4	to	to	ADP
biomedich-632	39	5	type	type	NOUN
biomedich-632	39	6	2	2	NUM
biomedich-632	39	7	and	and	CCONJ
biomedich-632	39	8	non	non	ADJ
biomedich-632	39	9	-	-	ADJ
biomedich-632	39	10	type	type	ADJ
biomedich-632	39	11	2	2	NUM
biomedich-632	39	12	inflammatory	inflammatory	ADJ
biomedich-632	39	13	reactions	reaction	NOUN
biomedich-632	39	14	in	in	ADP
biomedich-632	39	15	the	the	DET
biomedich-632	39	16	sinonasal	sinonasal	ADJ
biomedich-632	39	17	mucosa	mucosa	NOUN
biomedich-632	39	18	.	.	PUNCT
biomedich-632	40	1	osteitis	osteitis	NOUN
biomedich-632	40	2	features	feature	VERB
biomedich-632	40	3	bone	bone	NOUN
biomedich-632	40	4	inflammation	inflammation	NOUN
biomedich-632	40	5	,	,	PUNCT
biomedich-632	40	6	neo	neo	NOUN
biomedich-632	40	7	-	-	NOUN
biomedich-632	40	8	osteogenesis	osteogenesis	NOUN
biomedich-632	40	9	,	,	PUNCT
biomedich-632	40	10	and	and	CCONJ
biomedich-632	40	11	remodeling	remodeling	NOUN
biomedich-632	40	12	,	,	PUNCT
biomedich-632	40	13	involving	involve	VERB
biomedich-632	40	14	osteoclasts	osteoclast	NOUN
biomedich-632	40	15	in	in	ADP
biomedich-632	40	16	bone	bone	NOUN
biomedich-632	40	17	degradation	degradation	NOUN
biomedich-632	40	18	and	and	CCONJ
biomedich-632	40	19	osteoblasts	osteoblast	NOUN
biomedich-632	40	20	in	in	ADP
biomedich-632	40	21	bone	bone	NOUN
biomedich-632	40	22	replacement	replacement	NOUN
biomedich-632	40	23	.	.	PUNCT
biomedich-632	41	1	although	although	SCONJ
biomedich-632	41	2	the	the	DET
biomedich-632	41	3	exact	exact	ADJ
biomedich-632	41	4	mechanism	mechanism	NOUN
biomedich-632	41	5	of	of	ADP
biomedich-632	41	6	https://doi.org/10.14421/biomedich.2025.141.43-50	https://doi.org/10.14421/biomedich.2025.141.43-50	ADJ
biomedich-632	41	7	mailto:iriana_maharani@ub.ac.id	mailto:iriana_maharani@ub.ac.id	NOUN
biomedich-632	41	8	44	44	NUM
biomedich-632	41	9	biology	biology	NOUN
biomedich-632	41	10	,	,	PUNCT
biomedich-632	41	11	medicine	medicine	NOUN
biomedich-632	41	12	,	,	PUNCT
biomedich-632	41	13	&	&	CCONJ
biomedich-632	41	14	natural	natural	ADJ
biomedich-632	41	15	product	product	NOUN
biomedich-632	41	16	chemistry	chemistry	NOUN
biomedich-632	41	17	14	14	NUM
biomedich-632	41	18	(	(	PUNCT
biomedich-632	41	19	1	1	NUM
biomedich-632	41	20	)	)	PUNCT
biomedich-632	41	21	,	,	PUNCT
biomedich-632	41	22	2025	2025	NUM
biomedich-632	41	23	:	:	PUNCT
biomedich-632	41	24	43	43	NUM
biomedich-632	41	25	-	-	SYM
biomedich-632	41	26	50	50	NUM
biomedich-632	41	27	osteitis	osteitis	NOUN
biomedich-632	41	28	in	in	ADP
biomedich-632	41	29	crs	crs	PROPN
biomedich-632	41	30	is	be	AUX
biomedich-632	41	31	not	not	PART
biomedich-632	41	32	fully	fully	ADV
biomedich-632	41	33	understood	understand	VERB
biomedich-632	41	34	,	,	PUNCT
biomedich-632	41	35	persistent	persistent	ADJ
biomedich-632	41	36	mucosal	mucosal	NOUN
biomedich-632	41	37	inflammation	inflammation	NOUN
biomedich-632	41	38	is	be	AUX
biomedich-632	41	39	believed	believe	VERB
biomedich-632	41	40	to	to	PART
biomedich-632	41	41	cause	cause	VERB
biomedich-632	41	42	bone	bone	NOUN
biomedich-632	41	43	cell	cell	NOUN
biomedich-632	41	44	death	death	NOUN
biomedich-632	41	45	,	,	PUNCT
biomedich-632	41	46	leading	lead	VERB
biomedich-632	41	47	to	to	ADP
biomedich-632	41	48	neo	neo	NOUN
biomedich-632	41	49	-	-	NOUN
biomedich-632	41	50	osteogenesis	osteogenesis	NOUN
biomedich-632	41	51	and	and	CCONJ
biomedich-632	41	52	bone	bone	NOUN
biomedich-632	41	53	thickening	thickening	NOUN
biomedich-632	41	54	.	.	PUNCT
biomedich-632	42	1	chronic	chronic	ADJ
biomedich-632	42	2	inflammation	inflammation	NOUN
biomedich-632	42	3	,	,	PUNCT
biomedich-632	42	4	especially	especially	ADV
biomedich-632	42	5	type	type	NOUN
biomedich-632	42	6	2	2	NUM
biomedich-632	42	7	,	,	PUNCT
biomedich-632	42	8	is	be	AUX
biomedich-632	42	9	also	also	ADV
biomedich-632	42	10	linked	link	VERB
biomedich-632	42	11	to	to	ADP
biomedich-632	42	12	nasal	nasal	PROPN
biomedich-632	42	13	polyposis	polyposis	NOUN
biomedich-632	42	14	.	.	PUNCT
biomedich-632	43	1	bone	bone	NOUN
biomedich-632	43	2	thickening	thickening	NOUN
biomedich-632	43	3	in	in	ADP
biomedich-632	43	4	crs	crs	PROPN
biomedich-632	43	5	with	with	ADP
biomedich-632	43	6	osteitis	osteitis	NOUN
biomedich-632	43	7	is	be	AUX
biomedich-632	43	8	associated	associate	VERB
biomedich-632	43	9	with	with	ADP
biomedich-632	43	10	the	the	DET
biomedich-632	43	11	runt	runt	NOUN
biomedich-632	43	12	-	-	PUNCT
biomedich-632	43	13	related	relate	VERB
biomedich-632	43	14	transcription	transcription	NOUN
biomedich-632	43	15	factor	factor	NOUN
biomedich-632	43	16	2	2	NUM
biomedich-632	43	17	(	(	PUNCT
biomedich-632	43	18	runx2	runx2	NOUN
biomedich-632	43	19	)	)	PUNCT
biomedich-632	43	20	,	,	PUNCT
biomedich-632	43	21	crucial	crucial	ADJ
biomedich-632	43	22	for	for	ADP
biomedich-632	43	23	osteoblast	osteoblast	ADJ
biomedich-632	43	24	induction	induction	NOUN
biomedich-632	43	25	,	,	PUNCT
biomedich-632	43	26	proliferation	proliferation	NOUN
biomedich-632	43	27	,	,	PUNCT
biomedich-632	43	28	and	and	CCONJ
biomedich-632	43	29	maturation	maturation	NOUN
biomedich-632	43	30	(	(	PUNCT
biomedich-632	43	31	khalmuratova	khalmuratova	X
biomedich-632	43	32	et	et	PROPN
biomedich-632	43	33	al	al	PROPN
biomedich-632	43	34	.	.	PROPN
biomedich-632	43	35	,	,	PUNCT
biomedich-632	43	36	2019	2019	NUM
biomedich-632	43	37	)	)	PUNCT
biomedich-632	43	38	.	.	PUNCT
biomedich-632	44	1	crs	crs	NOUN
biomedich-632	44	2	patients	patient	NOUN
biomedich-632	44	3	with	with	ADP
biomedich-632	44	4	osteitis	osteitis	NOUN
biomedich-632	44	5	generally	generally	ADV
biomedich-632	44	6	have	have	VERB
biomedich-632	44	7	a	a	DET
biomedich-632	44	8	worse	bad	ADJ
biomedich-632	44	9	prognosis	prognosis	NOUN
biomedich-632	44	10	and	and	CCONJ
biomedich-632	44	11	a	a	DET
biomedich-632	44	12	higher	high	ADJ
biomedich-632	44	13	likelihood	likelihood	NOUN
biomedich-632	44	14	of	of	ADP
biomedich-632	44	15	postoperative	postoperative	ADJ
biomedich-632	44	16	recurrence	recurrence	NOUN
biomedich-632	44	17	compared	compare	VERB
biomedich-632	44	18	to	to	ADP
biomedich-632	44	19	those	those	PRON
biomedich-632	44	20	without	without	ADP
biomedich-632	44	21	osteitis	osteitis	NOUN
biomedich-632	44	22	(	(	PUNCT
biomedich-632	44	23	khalmuratova	khalmuratova	X
biomedich-632	44	24	et	et	PROPN
biomedich-632	44	25	al	al	PROPN
biomedich-632	44	26	.	.	PROPN
biomedich-632	44	27	,	,	PUNCT
biomedich-632	44	28	2019	2019	NUM
biomedich-632	44	29	)	)	PUNCT
biomedich-632	44	30	.	.	PUNCT
biomedich-632	45	1	the	the	DET
biomedich-632	45	2	degree	degree	NOUN
biomedich-632	45	3	of	of	ADP
biomedich-632	45	4	osteitis	osteitis	NOUN
biomedich-632	45	5	in	in	ADP
biomedich-632	45	6	crs	crs	PROPN
biomedich-632	45	7	can	can	AUX
biomedich-632	45	8	be	be	AUX
biomedich-632	45	9	assessed	assess	VERB
biomedich-632	45	10	through	through	ADP
biomedich-632	45	11	imaging	imaging	NOUN
biomedich-632	45	12	and	and	CCONJ
biomedich-632	45	13	histopathology	histopathology	NOUN
biomedich-632	45	14	.	.	PUNCT
biomedich-632	46	1	imaging	imaging	NOUN
biomedich-632	46	2	is	be	AUX
biomedich-632	46	3	more	more	ADV
biomedich-632	46	4	commonly	commonly	ADV
biomedich-632	46	5	used	use	VERB
biomedich-632	46	6	in	in	ADP
biomedich-632	46	7	clinical	clinical	ADJ
biomedich-632	46	8	settings	setting	NOUN
biomedich-632	46	9	due	due	ADP
biomedich-632	46	10	to	to	ADP
biomedich-632	46	11	its	its	PRON
biomedich-632	46	12	non	non	ADJ
biomedich-632	46	13	-	-	ADJ
biomedich-632	46	14	invasive	invasive	ADJ
biomedich-632	46	15	nature	nature	NOUN
biomedich-632	46	16	.	.	PUNCT
biomedich-632	47	1	computed	compute	VERB
biomedich-632	47	2	tomography	tomography	NOUN
biomedich-632	47	3	(	(	PUNCT
biomedich-632	47	4	ct	ct	NOUN
biomedich-632	47	5	)	)	PUNCT
biomedich-632	47	6	scans	scan	NOUN
biomedich-632	47	7	are	be	AUX
biomedich-632	47	8	frequently	frequently	ADV
biomedich-632	47	9	employed	employ	VERB
biomedich-632	47	10	to	to	PART
biomedich-632	47	11	evaluate	evaluate	VERB
biomedich-632	47	12	osteitis	osteitis	NOUN
biomedich-632	47	13	in	in	ADP
biomedich-632	47	14	crs	crs	PROPN
biomedich-632	47	15	(	(	PUNCT
biomedich-632	47	16	khalmuratova	khalmuratova	X
biomedich-632	47	17	et	et	PROPN
biomedich-632	47	18	al	al	PROPN
biomedich-632	47	19	.	.	PROPN
biomedich-632	47	20	,	,	PUNCT
biomedich-632	47	21	2019	2019	NUM
biomedich-632	47	22	)	)	PUNCT
biomedich-632	47	23	.	.	PUNCT
biomedich-632	48	1	ct	ct	PROPN
biomedich-632	48	2	scan	scan	PROPN
biomedich-632	48	3	results	result	NOUN
biomedich-632	48	4	are	be	AUX
biomedich-632	48	5	used	use	VERB
biomedich-632	48	6	to	to	ADP
biomedich-632	48	7	grade	grade	NOUN
biomedich-632	48	8	osteitis	osteitis	NOUN
biomedich-632	48	9	based	base	VERB
biomedich-632	48	10	on	on	ADP
biomedich-632	48	11	various	various	ADJ
biomedich-632	48	12	scoring	scoring	NOUN
biomedich-632	48	13	criteria	criterion	NOUN
biomedich-632	48	14	,	,	PUNCT
biomedich-632	48	15	including	include	VERB
biomedich-632	48	16	the	the	DET
biomedich-632	48	17	kennedy	kennedy	PROPN
biomedich-632	48	18	osteitis	osteitis	PROPN
biomedich-632	48	19	score	score	NOUN
biomedich-632	48	20	(	(	PUNCT
biomedich-632	48	21	kos	kos	PROPN
biomedich-632	48	22	)	)	PUNCT
biomedich-632	48	23	,	,	PUNCT
biomedich-632	48	24	global	global	ADJ
biomedich-632	48	25	osteitis	osteitis	NOUN
biomedich-632	48	26	scoring	scoring	NOUN
biomedich-632	48	27	scale	scale	NOUN
biomedich-632	48	28	(	(	PUNCT
biomedich-632	48	29	goss	goss	PROPN
biomedich-632	48	30	)	)	PUNCT
biomedich-632	48	31	,	,	PUNCT
biomedich-632	48	32	and	and	CCONJ
biomedich-632	48	33	modified	modify	VERB
biomedich-632	48	34	goss	goss	PROPN
biomedich-632	48	35	.	.	PUNCT
biomedich-632	49	1	goss	goss	PROPN
biomedich-632	49	2	is	be	AUX
biomedich-632	49	3	the	the	DET
biomedich-632	49	4	most	most	ADV
biomedich-632	49	5	commonly	commonly	ADV
biomedich-632	49	6	used	use	VERB
biomedich-632	49	7	as	as	SCONJ
biomedich-632	49	8	it	it	PRON
biomedich-632	49	9	provides	provide	VERB
biomedich-632	49	10	a	a	DET
biomedich-632	49	11	detailed	detailed	ADJ
biomedich-632	49	12	assessment	assessment	NOUN
biomedich-632	49	13	of	of	ADP
biomedich-632	49	14	the	the	DET
biomedich-632	49	15	involvement	involvement	NOUN
biomedich-632	49	16	and	and	CCONJ
biomedich-632	49	17	thickness	thickness	NOUN
biomedich-632	49	18	of	of	ADP
biomedich-632	49	19	the	the	DET
biomedich-632	49	20	walls	wall	NOUN
biomedich-632	49	21	of	of	ADP
biomedich-632	49	22	10	10	NUM
biomedich-632	49	23	sinuses	sinus	NOUN
biomedich-632	49	24	(	(	PUNCT
biomedich-632	49	25	leung	leung	PROPN
biomedich-632	49	26	et	et	PROPN
biomedich-632	49	27	al	al	PROPN
biomedich-632	49	28	.	.	PROPN
biomedich-632	49	29	,	,	PUNCT
biomedich-632	49	30	2016	2016	NUM
biomedich-632	49	31	)	)	PUNCT
biomedich-632	49	32	.	.	PUNCT
biomedich-632	50	1	bone	bone	NOUN
biomedich-632	50	2	morphogenetic	morphogenetic	ADJ
biomedich-632	50	3	protein	protein	NOUN
biomedich-632	50	4	2	2	NUM
biomedich-632	50	5	(	(	PUNCT
biomedich-632	50	6	bmp-2	bmp-2	NOUN
biomedich-632	50	7	)	)	PUNCT
biomedich-632	50	8	is	be	AUX
biomedich-632	50	9	a	a	DET
biomedich-632	50	10	multifunctional	multifunctional	ADJ
biomedich-632	50	11	growth	growth	NOUN
biomedich-632	50	12	factor	factor	NOUN
biomedich-632	50	13	in	in	ADP
biomedich-632	50	14	the	the	DET
biomedich-632	50	15	transforming	transform	VERB
biomedich-632	50	16	growth	growth	NOUN
biomedich-632	50	17	factor	factor	NOUN
biomedich-632	50	18	-	-	PUNCT
biomedich-632	50	19	beta	beta	NOUN
biomedich-632	50	20	(	(	PUNCT
biomedich-632	50	21	tgf	tgf	PROPN
biomedich-632	50	22	-	-	PUNCT
biomedich-632	50	23	β	β	NOUN
biomedich-632	50	24	)	)	PUNCT
biomedich-632	50	25	superfamily	superfamily	NOUN
biomedich-632	50	26	.	.	PUNCT
biomedich-632	51	1	bmp-2	bmp-2	PUNCT
biomedich-632	51	2	is	be	AUX
biomedich-632	51	3	vital	vital	ADJ
biomedich-632	51	4	for	for	ADP
biomedich-632	51	5	bone	bone	NOUN
biomedich-632	51	6	formation	formation	NOUN
biomedich-632	51	7	and	and	CCONJ
biomedich-632	51	8	remodeling	remodel	VERB
biomedich-632	51	9	through	through	ADP
biomedich-632	51	10	the	the	DET
biomedich-632	51	11	regulation	regulation	NOUN
biomedich-632	51	12	of	of	ADP
biomedich-632	51	13	osteoblasts	osteoblast	NOUN
biomedich-632	51	14	and	and	CCONJ
biomedich-632	51	15	osteoclasts	osteoclast	NOUN
biomedich-632	51	16	(	(	PUNCT
biomedich-632	51	17	kim	kim	PROPN
biomedich-632	51	18	et	et	PROPN
biomedich-632	51	19	al	al	PROPN
biomedich-632	51	20	.	.	PROPN
biomedich-632	51	21	,	,	PUNCT
biomedich-632	51	22	2021	2021	NUM
biomedich-632	51	23	)	)	PUNCT
biomedich-632	51	24	.	.	PUNCT
biomedich-632	52	1	it	it	PRON
biomedich-632	52	2	can	can	AUX
biomedich-632	52	3	also	also	ADV
biomedich-632	52	4	activate	activate	VERB
biomedich-632	52	5	runx2	runx2	NOUN
biomedich-632	52	6	via	via	ADP
biomedich-632	52	7	the	the	DET
biomedich-632	52	8	smad1	smad1	PROPN
biomedich-632	52	9	pathway	pathway	NOUN
biomedich-632	52	10	.	.	PUNCT
biomedich-632	53	1	when	when	SCONJ
biomedich-632	53	2	bmp-2	bmp-2	PUNCT
biomedich-632	53	3	docks	dock	NOUN
biomedich-632	53	4	with	with	ADP
biomedich-632	53	5	its	its	PRON
biomedich-632	53	6	receptor	receptor	NOUN
biomedich-632	53	7	,	,	PUNCT
biomedich-632	53	8	it	it	PRON
biomedich-632	53	9	phosphorylates	phosphorylate	VERB
biomedich-632	53	10	smad1	smad1	PROPN
biomedich-632	53	11	,	,	PUNCT
biomedich-632	53	12	which	which	PRON
biomedich-632	53	13	then	then	ADV
biomedich-632	53	14	activates	activate	VERB
biomedich-632	53	15	runx2	runx2	NOUN
biomedich-632	53	16	,	,	PUNCT
biomedich-632	53	17	playing	play	VERB
biomedich-632	53	18	a	a	DET
biomedich-632	53	19	crucial	crucial	ADJ
biomedich-632	53	20	role	role	NOUN
biomedich-632	53	21	in	in	ADP
biomedich-632	53	22	osteoblast	osteoblast	ADJ
biomedich-632	53	23	induction	induction	NOUN
biomedich-632	53	24	,	,	PUNCT
biomedich-632	53	25	proliferation	proliferation	NOUN
biomedich-632	53	26	,	,	PUNCT
biomedich-632	53	27	and	and	CCONJ
biomedich-632	53	28	maturation	maturation	NOUN
biomedich-632	53	29	(	(	PUNCT
biomedich-632	53	30	cho	cho	PROPN
biomedich-632	53	31	&	&	CCONJ
biomedich-632	53	32	kwun	kwun	PROPN
biomedich-632	53	33	,	,	PUNCT
biomedich-632	53	34	2018	2018	NUM
biomedich-632	53	35	)	)	PUNCT
biomedich-632	53	36	.	.	PUNCT
biomedich-632	54	1	currently	currently	ADV
biomedich-632	54	2	,	,	PUNCT
biomedich-632	54	3	no	no	DET
biomedich-632	54	4	studies	study	NOUN
biomedich-632	54	5	have	have	AUX
biomedich-632	54	6	directly	directly	ADV
biomedich-632	54	7	examined	examine	VERB
biomedich-632	54	8	the	the	DET
biomedich-632	54	9	relationship	relationship	NOUN
biomedich-632	54	10	between	between	ADP
biomedich-632	54	11	bmp-2	bmp-2	NOUN
biomedich-632	54	12	levels	level	NOUN
biomedich-632	54	13	and	and	CCONJ
biomedich-632	54	14	the	the	DET
biomedich-632	54	15	degree	degree	NOUN
biomedich-632	54	16	of	of	ADP
biomedich-632	54	17	osteitis	osteitis	NOUN
biomedich-632	54	18	measured	measure	VERB
biomedich-632	54	19	using	use	VERB
biomedich-632	54	20	goss	goss	PROPN
biomedich-632	54	21	in	in	ADP
biomedich-632	54	22	crs	crs	PROPN
biomedich-632	54	23	patients	patient	NOUN
biomedich-632	54	24	with	with	ADP
biomedich-632	54	25	and	and	CCONJ
biomedich-632	54	26	without	without	ADP
biomedich-632	54	27	nasal	nasal	PROPN
biomedich-632	54	28	polyps	polyp	NOUN
biomedich-632	54	29	.	.	PUNCT
biomedich-632	55	1	given	give	VERB
biomedich-632	55	2	the	the	DET
biomedich-632	55	3	relationship	relationship	NOUN
biomedich-632	55	4	between	between	ADP
biomedich-632	55	5	bmp-2	bmp-2	NUM
biomedich-632	55	6	and	and	CCONJ
biomedich-632	55	7	runx2	runx2	NOUN
biomedich-632	55	8	and	and	CCONJ
biomedich-632	55	9	the	the	DET
biomedich-632	55	10	role	role	NOUN
biomedich-632	55	11	of	of	ADP
biomedich-632	55	12	runx2	runx2	NOUN
biomedich-632	55	13	in	in	ADP
biomedich-632	55	14	osteitis	osteitis	PROPN
biomedich-632	55	15	in	in	ADP
biomedich-632	55	16	crs	crs	PROPN
biomedich-632	55	17	,	,	PUNCT
biomedich-632	55	18	this	this	DET
biomedich-632	55	19	study	study	NOUN
biomedich-632	55	20	aims	aim	VERB
biomedich-632	55	21	to	to	PART
biomedich-632	55	22	investigate	investigate	VERB
biomedich-632	55	23	the	the	DET
biomedich-632	55	24	correlation	correlation	NOUN
biomedich-632	55	25	between	between	ADP
biomedich-632	55	26	bmp-2	bmp-2	NUM
biomedich-632	55	27	levels	level	NOUN
biomedich-632	55	28	and	and	CCONJ
biomedich-632	55	29	the	the	DET
biomedich-632	55	30	degree	degree	NOUN
biomedich-632	55	31	of	of	ADP
biomedich-632	55	32	osteitis	osteitis	NOUN
biomedich-632	55	33	measured	measure	VERB
biomedich-632	55	34	using	use	VERB
biomedich-632	55	35	goss	goss	PROPN
biomedich-632	55	36	in	in	ADP
biomedich-632	55	37	crs	crs	PROPN
biomedich-632	55	38	patients	patient	NOUN
biomedich-632	55	39	with	with	ADP
biomedich-632	55	40	and	and	CCONJ
biomedich-632	55	41	without	without	ADP
biomedich-632	55	42	nasal	nasal	PROPN
biomedich-632	55	43	polyps	polyp	NOUN
biomedich-632	55	44	.	.	PUNCT
biomedich-632	56	1	understanding	understand	VERB
biomedich-632	56	2	the	the	DET
biomedich-632	56	3	relationship	relationship	NOUN
biomedich-632	56	4	between	between	ADP
biomedich-632	56	5	bmp-2	bmp-2	NOUN
biomedich-632	56	6	levels	level	NOUN
biomedich-632	56	7	and	and	CCONJ
biomedich-632	56	8	goss	goss	PROPN
biomedich-632	56	9	could	could	AUX
biomedich-632	56	10	lead	lead	VERB
biomedich-632	56	11	to	to	ADP
biomedich-632	56	12	the	the	DET
biomedich-632	56	13	development	development	NOUN
biomedich-632	56	14	of	of	ADP
biomedich-632	56	15	targeted	target	VERB
biomedich-632	56	16	therapies	therapy	NOUN
biomedich-632	56	17	for	for	ADP
biomedich-632	56	18	osteitis	osteitis	NOUN
biomedich-632	56	19	in	in	ADP
biomedich-632	56	20	chronic	chronic	ADJ
biomedich-632	56	21	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	56	22	.	.	PUNCT
biomedich-632	57	1	this	this	DET
biomedich-632	57	2	insight	insight	NOUN
biomedich-632	57	3	might	might	AUX
biomedich-632	57	4	also	also	ADV
biomedich-632	57	5	help	help	VERB
biomedich-632	57	6	prevent	prevent	VERB
biomedich-632	57	7	the	the	DET
biomedich-632	57	8	recurrence	recurrence	NOUN
biomedich-632	57	9	of	of	ADP
biomedich-632	57	10	chronic	chronic	ADJ
biomedich-632	57	11	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	57	12	after	after	ADP
biomedich-632	57	13	surgery	surgery	NOUN
biomedich-632	57	14	.	.	PUNCT
biomedich-632	58	1	patients	patient	NOUN
biomedich-632	58	2	and	and	CCONJ
biomedich-632	58	3	methods	method	NOUN
biomedich-632	58	4	this	this	DET
biomedich-632	58	5	cross	cross	ADJ
biomedich-632	58	6	-	-	ADJ
biomedich-632	58	7	sectional	sectional	ADJ
biomedich-632	58	8	study	study	NOUN
biomedich-632	58	9	was	be	AUX
biomedich-632	58	10	carried	carry	VERB
biomedich-632	58	11	out	out	ADP
biomedich-632	58	12	between	between	ADP
biomedich-632	58	13	may	may	PROPN
biomedich-632	58	14	1	1	NUM
biomedich-632	58	15	,	,	PUNCT
biomedich-632	58	16	2022	2022	NUM
biomedich-632	58	17	,	,	PUNCT
biomedich-632	58	18	and	and	CCONJ
biomedich-632	58	19	november	november	PROPN
biomedich-632	58	20	30	30	NUM
biomedich-632	58	21	,	,	PUNCT
biomedich-632	58	22	2022	2022	NUM
biomedich-632	58	23	,	,	PUNCT
biomedich-632	58	24	across	across	ADP
biomedich-632	58	25	various	various	ADJ
biomedich-632	58	26	departments	department	NOUN
biomedich-632	58	27	at	at	ADP
biomedich-632	58	28	dr	dr	PROPN
biomedich-632	58	29	.	.	PROPN
biomedich-632	58	30	saiful	saiful	PROPN
biomedich-632	58	31	anwar	anwar	PROPN
biomedich-632	58	32	general	general	PROPN
biomedich-632	58	33	hospital	hospital	PROPN
biomedich-632	58	34	,	,	PUNCT
biomedich-632	58	35	including	include	VERB
biomedich-632	58	36	the	the	DET
biomedich-632	58	37	local	local	ADJ
biomedich-632	58	38	and	and	CCONJ
biomedich-632	58	39	central	central	ADJ
biomedich-632	58	40	operating	operate	VERB
biomedich-632	58	41	rooms	room	NOUN
biomedich-632	58	42	of	of	ADP
biomedich-632	58	43	the	the	DET
biomedich-632	58	44	otorhinolaryngology	otorhinolaryngology	NOUN
biomedich-632	58	45	head	head	NOUN
biomedich-632	58	46	and	and	CCONJ
biomedich-632	58	47	neck	neck	NOUN
biomedich-632	58	48	surgery	surgery	NOUN
biomedich-632	58	49	department	department	NOUN
biomedich-632	58	50	,	,	PUNCT
biomedich-632	58	51	the	the	DET
biomedich-632	58	52	radiology	radiology	NOUN
biomedich-632	58	53	department	department	NOUN
biomedich-632	58	54	,	,	PUNCT
biomedich-632	58	55	and	and	CCONJ
biomedich-632	58	56	the	the	DET
biomedich-632	58	57	biomedical	biomedical	ADJ
biomedich-632	58	58	laboratory	laboratory	NOUN
biomedich-632	58	59	of	of	ADP
biomedich-632	58	60	the	the	DET
biomedich-632	58	61	faculty	faculty	NOUN
biomedich-632	58	62	of	of	ADP
biomedich-632	58	63	medicine	medicine	NOUN
biomedich-632	58	64	at	at	ADP
biomedich-632	58	65	universitas	universitas	PROPN
biomedich-632	58	66	brawijaya	brawijaya	PROPN
biomedich-632	58	67	,	,	PUNCT
biomedich-632	58	68	malang	malang	PROPN
biomedich-632	58	69	,	,	PUNCT
biomedich-632	58	70	indonesia	indonesia	PROPN
biomedich-632	58	71	.	.	PUNCT
biomedich-632	59	1	the	the	DET
biomedich-632	59	2	study	study	NOUN
biomedich-632	59	3	received	receive	VERB
biomedich-632	59	4	approval	approval	NOUN
biomedich-632	59	5	from	from	ADP
biomedich-632	59	6	the	the	DET
biomedich-632	59	7	medical	medical	ADJ
biomedich-632	59	8	ethics	ethic	NOUN
biomedich-632	59	9	committee	committee	PROPN
biomedich-632	59	10	of	of	ADP
biomedich-632	59	11	dr	dr	PROPN
biomedich-632	59	12	.	.	PROPN
biomedich-632	59	13	saiful	saiful	PROPN
biomedich-632	59	14	anwar	anwar	PROPN
biomedich-632	59	15	general	general	PROPN
biomedich-632	59	16	hospital	hospital	PROPN
biomedich-632	59	17	(	(	PUNCT
biomedich-632	59	18	no	no	INTJ
biomedich-632	59	19	.	.	PUNCT
biomedich-632	60	1	400/217	400/217	NOUN
biomedich-632	60	2	/	/	SYM
biomedich-632	60	3	k.3/102.7/2022	k.3/102.7/2022	NOUN
biomedich-632	60	4	)	)	PUNCT
biomedich-632	60	5	.	.	PUNCT
biomedich-632	61	1	the	the	DET
biomedich-632	61	2	study	study	NOUN
biomedich-632	61	3	population	population	NOUN
biomedich-632	61	4	consisted	consist	VERB
biomedich-632	61	5	of	of	ADP
biomedich-632	61	6	all	all	DET
biomedich-632	61	7	patients	patient	NOUN
biomedich-632	61	8	from	from	ADP
biomedich-632	61	9	the	the	DET
biomedich-632	61	10	rhinology	rhinology	NOUN
biomedich-632	61	11	division	division	NOUN
biomedich-632	61	12	who	who	PRON
biomedich-632	61	13	were	be	AUX
biomedich-632	61	14	admitted	admit	VERB
biomedich-632	61	15	to	to	ADP
biomedich-632	61	16	the	the	DET
biomedich-632	61	17	medical	medical	ADJ
biomedich-632	61	18	ward	ward	NOUN
biomedich-632	61	19	of	of	ADP
biomedich-632	61	20	dr	dr	PROPN
biomedich-632	61	21	.	.	PROPN
biomedich-632	61	22	saiful	saiful	PROPN
biomedich-632	61	23	anwar	anwar	PROPN
biomedich-632	61	24	general	general	PROPN
biomedich-632	61	25	hospital	hospital	PROPN
biomedich-632	61	26	during	during	ADP
biomedich-632	61	27	the	the	DET
biomedich-632	61	28	study	study	NOUN
biomedich-632	61	29	period	period	NOUN
biomedich-632	61	30	.	.	PUNCT
biomedich-632	62	1	the	the	DET
biomedich-632	62	2	inclusion	inclusion	NOUN
biomedich-632	62	3	criteria	criterion	NOUN
biomedich-632	62	4	for	for	ADP
biomedich-632	62	5	this	this	DET
biomedich-632	62	6	study	study	NOUN
biomedich-632	62	7	are	be	AUX
biomedich-632	62	8	adult	adult	NOUN
biomedich-632	62	9	crs	crs	NOUN
biomedich-632	62	10	patients	patient	NOUN
biomedich-632	62	11	over	over	ADP
biomedich-632	62	12	18	18	NUM
biomedich-632	62	13	years	year	NOUN
biomedich-632	62	14	old	old	ADJ
biomedich-632	62	15	according	accord	VERB
biomedich-632	62	16	to	to	ADP
biomedich-632	62	17	clinical	clinical	ADJ
biomedich-632	62	18	criteria	criterion	NOUN
biomedich-632	62	19	from	from	ADP
biomedich-632	62	20	the	the	DET
biomedich-632	62	21	european	european	PROPN
biomedich-632	62	22	position	position	NOUN
biomedich-632	62	23	paper	paper	NOUN
biomedich-632	62	24	on	on	ADP
biomedich-632	62	25	rhinosinusitis	rhinosinusitis	PROPN
biomedich-632	62	26	and	and	CCONJ
biomedich-632	62	27	nasal	nasal	ADJ
biomedich-632	62	28	polyps	polyp	NOUN
biomedich-632	62	29	(	(	PUNCT
biomedich-632	62	30	epos	epos	PROPN
biomedich-632	62	31	)	)	PUNCT
biomedich-632	62	32	2020	2020	NUM
biomedich-632	62	33	,	,	PUNCT
biomedich-632	62	34	crs	crs	NOUN
biomedich-632	62	35	patients	patient	NOUN
biomedich-632	62	36	who	who	PRON
biomedich-632	62	37	have	have	AUX
biomedich-632	62	38	never	never	ADV
biomedich-632	62	39	undergone	undergo	VERB
biomedich-632	62	40	functional	functional	ADJ
biomedich-632	62	41	endoscopic	endoscopic	ADJ
biomedich-632	62	42	sinus	sinus	NOUN
biomedich-632	62	43	surgery	surgery	NOUN
biomedich-632	62	44	(	(	PUNCT
biomedich-632	62	45	fess	fess	NOUN
biomedich-632	62	46	)	)	PUNCT
biomedich-632	62	47	before	before	ADV
biomedich-632	62	48	,	,	PUNCT
biomedich-632	62	49	and	and	CCONJ
biomedich-632	62	50	who	who	PRON
biomedich-632	62	51	have	have	AUX
biomedich-632	62	52	not	not	PART
biomedich-632	62	53	used	use	VERB
biomedich-632	62	54	corticosteroids	corticosteroid	NOUN
biomedich-632	62	55	or	or	CCONJ
biomedich-632	62	56	antibiotics	antibiotic	NOUN
biomedich-632	62	57	within	within	ADP
biomedich-632	62	58	4	4	NUM
biomedich-632	62	59	weeks	week	NOUN
biomedich-632	62	60	prior	prior	ADV
biomedich-632	62	61	to	to	ADP
biomedich-632	62	62	specimen	speciman	NOUN
biomedich-632	62	63	collection	collection	NOUN
biomedich-632	62	64	.	.	PUNCT
biomedich-632	63	1	control	control	NOUN
biomedich-632	63	2	patients	patient	NOUN
biomedich-632	63	3	over	over	ADP
biomedich-632	63	4	18	18	NUM
biomedich-632	63	5	years	year	NOUN
biomedich-632	63	6	old	old	ADJ
biomedich-632	63	7	diagnosed	diagnose	VERB
biomedich-632	63	8	with	with	ADP
biomedich-632	63	9	a	a	DET
biomedich-632	63	10	rhinology	rhinology	NOUN
biomedich-632	63	11	-	-	PUNCT
biomedich-632	63	12	related	relate	VERB
biomedich-632	63	13	condition	condition	NOUN
biomedich-632	63	14	other	other	ADJ
biomedich-632	63	15	than	than	ADP
biomedich-632	63	16	chronic	chronic	ADJ
biomedich-632	63	17	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	63	18	,	,	PUNCT
biomedich-632	63	19	with	with	ADP
biomedich-632	63	20	or	or	CCONJ
biomedich-632	63	21	without	without	ADP
biomedich-632	63	22	polyps	polyp	NOUN
biomedich-632	63	23	,	,	PUNCT
biomedich-632	63	24	who	who	PRON
biomedich-632	63	25	require	require	VERB
biomedich-632	63	26	surgical	surgical	ADJ
biomedich-632	63	27	intervention	intervention	NOUN
biomedich-632	63	28	.	.	PUNCT
biomedich-632	64	1	exclusion	exclusion	NOUN
biomedich-632	64	2	criteria	criterion	NOUN
biomedich-632	64	3	for	for	ADP
biomedich-632	64	4	this	this	DET
biomedich-632	64	5	study	study	NOUN
biomedich-632	64	6	are	be	AUX
biomedich-632	64	7	crs	crs	NOUN
biomedich-632	64	8	patients	patient	NOUN
biomedich-632	64	9	involving	involve	VERB
biomedich-632	64	10	only	only	ADV
biomedich-632	64	11	the	the	DET
biomedich-632	64	12	posterior	posterior	ADJ
biomedich-632	64	13	paranasal	paranasal	ADJ
biomedich-632	64	14	sinuses	sinus	NOUN
biomedich-632	64	15	,	,	PUNCT
biomedich-632	64	16	patients	patient	NOUN
biomedich-632	64	17	who	who	PRON
biomedich-632	64	18	do	do	AUX
biomedich-632	64	19	not	not	PART
biomedich-632	64	20	consent	consent	VERB
biomedich-632	64	21	to	to	PART
biomedich-632	64	22	participate	participate	VERB
biomedich-632	64	23	in	in	ADP
biomedich-632	64	24	the	the	DET
biomedich-632	64	25	study	study	NOUN
biomedich-632	64	26	,	,	PUNCT
biomedich-632	64	27	and	and	CCONJ
biomedich-632	64	28	control	control	NOUN
biomedich-632	64	29	patients	patient	NOUN
biomedich-632	64	30	under	under	ADP
biomedich-632	64	31	18	18	NUM
biomedich-632	64	32	years	year	NOUN
biomedich-632	64	33	old	old	ADJ
biomedich-632	64	34	,	,	PUNCT
biomedich-632	64	35	those	those	PRON
biomedich-632	64	36	with	with	ADP
biomedich-632	64	37	allergic	allergic	ADJ
biomedich-632	64	38	rhinitis	rhinitis	NOUN
biomedich-632	64	39	,	,	PUNCT
biomedich-632	64	40	or	or	CCONJ
biomedich-632	64	41	those	those	PRON
biomedich-632	64	42	who	who	PRON
biomedich-632	64	43	have	have	AUX
biomedich-632	64	44	used	use	VERB
biomedich-632	64	45	corticosteroids	corticosteroid	NOUN
biomedich-632	64	46	or	or	CCONJ
biomedich-632	64	47	antibiotics	antibiotic	NOUN
biomedich-632	64	48	within	within	ADP
biomedich-632	64	49	4	4	NUM
biomedich-632	64	50	weeks	week	NOUN
biomedich-632	64	51	before	before	ADP
biomedich-632	64	52	specimen	speciman	NOUN
biomedich-632	64	53	collection	collection	NOUN
biomedich-632	64	54	.	.	PUNCT
biomedich-632	65	1	age	age	NOUN
biomedich-632	65	2	,	,	PUNCT
biomedich-632	65	3	sex	sex	NOUN
biomedich-632	65	4	,	,	PUNCT
biomedich-632	65	5	main	main	ADJ
biomedich-632	65	6	symptoms	symptom	NOUN
biomedich-632	65	7	(	(	PUNCT
biomedich-632	65	8	nasal	nasal	ADJ
biomedich-632	65	9	blockage	blockage	NOUN
biomedich-632	65	10	/	/	SYM
biomedich-632	65	11	obstruction	obstruction	NOUN
biomedich-632	65	12	/	/	SYM
biomedich-632	65	13	congestion	congestion	NOUN
biomedich-632	65	14	,	,	PUNCT
biomedich-632	65	15	nasal	nasal	ADJ
biomedich-632	65	16	discharge	discharge	NOUN
biomedich-632	65	17	,	,	PUNCT
biomedich-632	65	18	facial	facial	ADJ
biomedich-632	65	19	pain	pain	NOUN
biomedich-632	65	20	/	/	SYM
biomedich-632	65	21	pressure	pressure	NOUN
biomedich-632	65	22	,	,	PUNCT
biomedich-632	65	23	reduction	reduction	NOUN
biomedich-632	65	24	/	/	SYM
biomedich-632	65	25	loss	loss	NOUN
biomedich-632	65	26	of	of	ADP
biomedich-632	65	27	smell	smell	NOUN
biomedich-632	65	28	,	,	PUNCT
biomedich-632	65	29	patient	patient	ADJ
biomedich-632	65	30	complaints	complaint	NOUN
biomedich-632	65	31	duration	duration	NOUN
biomedich-632	65	32	,	,	PUNCT
biomedich-632	65	33	biopsy	biopsy	NOUN
biomedich-632	65	34	of	of	ADP
biomedich-632	65	35	the	the	DET
biomedich-632	65	36	uncinate	uncinate	ADJ
biomedich-632	65	37	process	process	NOUN
biomedich-632	65	38	tissue	tissue	NOUN
biomedich-632	65	39	were	be	AUX
biomedich-632	65	40	obtained	obtain	VERB
biomedich-632	65	41	.	.	PUNCT
biomedich-632	66	1	the	the	DET
biomedich-632	66	2	uncinate	uncinate	ADJ
biomedich-632	66	3	process	process	NOUN
biomedich-632	66	4	tissues	tissue	NOUN
biomedich-632	66	5	were	be	AUX
biomedich-632	66	6	examined	examine	VERB
biomedich-632	66	7	using	use	VERB
biomedich-632	66	8	enzyme	enzyme	NOUN
biomedich-632	66	9	-	-	PUNCT
biomedich-632	66	10	linked	link	VERB
biomedich-632	66	11	immunosorbent	immunosorbent	NOUN
biomedich-632	66	12	assay	assay	PROPN
biomedich-632	66	13	(	(	PUNCT
biomedich-632	66	14	elisa	elisa	NOUN
biomedich-632	66	15	)	)	PUNCT
biomedich-632	66	16	according	accord	VERB
biomedich-632	66	17	to	to	ADP
biomedich-632	66	18	the	the	DET
biomedich-632	66	19	goss	goss	PROPN
biomedich-632	66	20	method	method	NOUN
biomedich-632	66	21	to	to	PART
biomedich-632	66	22	determine	determine	VERB
biomedich-632	66	23	the	the	DET
biomedich-632	66	24	bmp-2	bmp-2	NUM
biomedich-632	66	25	levels	level	NOUN
biomedich-632	66	26	.	.	PUNCT
biomedich-632	67	1	the	the	DET
biomedich-632	67	2	osteitis	osteitis	NOUN
biomedich-632	67	3	of	of	ADP
biomedich-632	67	4	the	the	DET
biomedich-632	67	5	paranasal	paranasal	ADJ
biomedich-632	67	6	sinus	sinus	NOUN
biomedich-632	67	7	walls	wall	NOUN
biomedich-632	67	8	was	be	AUX
biomedich-632	67	9	assessed	assess	VERB
biomedich-632	67	10	with	with	ADP
biomedich-632	67	11	a	a	DET
biomedich-632	67	12	ct	ct	NOUN
biomedich-632	67	13	scan	scan	NOUN
biomedich-632	67	14	and	and	CCONJ
biomedich-632	67	15	quantified	quantify	VERB
biomedich-632	67	16	using	use	VERB
biomedich-632	67	17	the	the	DET
biomedich-632	67	18	goss	goss	PROPN
biomedich-632	67	19	method	method	NOUN
biomedich-632	67	20	.	.	PUNCT
biomedich-632	68	1	ct	ct	PROPN
biomedich-632	68	2	scan	scan	NOUN
biomedich-632	68	3	of	of	ADP
biomedich-632	68	4	the	the	DET
biomedich-632	68	5	paranasal	paranasal	ADJ
biomedich-632	68	6	sinuses	sinus	NOUN
biomedich-632	68	7	was	be	AUX
biomedich-632	68	8	performed	perform	VERB
biomedich-632	68	9	without	without	ADP
biomedich-632	68	10	contrast	contrast	NOUN
biomedich-632	68	11	,	,	PUNCT
biomedich-632	68	12	using	use	VERB
biomedich-632	68	13	bone	bone	NOUN
biomedich-632	68	14	setting	setting	NOUN
biomedich-632	68	15	,	,	PUNCT
biomedich-632	68	16	with	with	ADP
biomedich-632	68	17	axial	axial	ADJ
biomedich-632	68	18	,	,	PUNCT
biomedich-632	68	19	coronal	coronal	NOUN
biomedich-632	68	20	,	,	PUNCT
biomedich-632	68	21	and	and	CCONJ
biomedich-632	68	22	parasagittal	parasagittal	ADJ
biomedich-632	68	23	slices	slice	NOUN
biomedich-632	68	24	,	,	PUNCT
biomedich-632	68	25	with	with	ADP
biomedich-632	68	26	a	a	DET
biomedich-632	68	27	thickness	thickness	NOUN
biomedich-632	68	28	of	of	ADP
biomedich-632	68	29	1	1	NUM
biomedich-632	68	30	-	-	SYM
biomedich-632	68	31	3	3	NUM
biomedich-632	68	32	mm	mm	NOUN
biomedich-632	68	33	per	per	ADP
biomedich-632	68	34	slice	slice	NOUN
biomedich-632	68	35	,	,	PUNCT
biomedich-632	68	36	each	each	DET
biomedich-632	68	37	component	component	NOUN
biomedich-632	68	38	and	and	CCONJ
biomedich-632	68	39	the	the	DET
biomedich-632	68	40	total	total	ADJ
biomedich-632	68	41	goss	goss	PROPN
biomedich-632	68	42	were	be	AUX
biomedich-632	68	43	calculated	calculate	VERB
biomedich-632	68	44	using	use	VERB
biomedich-632	68	45	the	the	DET
biomedich-632	68	46	horos	horo	NOUN
biomedich-632	68	47	3.3.6	3.3.6	NUM
biomedich-632	68	48	software	software	NOUN
biomedich-632	68	49	.	.	PUNCT
biomedich-632	69	1	data	datum	NOUN
biomedich-632	69	2	were	be	AUX
biomedich-632	69	3	analyzed	analyze	VERB
biomedich-632	69	4	using	use	VERB
biomedich-632	69	5	the	the	DET
biomedich-632	69	6	spearman	spearman	NOUN
biomedich-632	69	7	correlation	correlation	NOUN
biomedich-632	69	8	test	test	NOUN
biomedich-632	69	9	with	with	ADP
biomedich-632	69	10	a	a	DET
biomedich-632	69	11	95	95	NUM
biomedich-632	69	12	%	%	NOUN
biomedich-632	69	13	confidence	confidence	NOUN
biomedich-632	69	14	interval	interval	NOUN
biomedich-632	69	15	(	(	PUNCT
biomedich-632	69	16	ci	ci	NOUN
biomedich-632	69	17	)	)	PUNCT
biomedich-632	69	18	and	and	CCONJ
biomedich-632	69	19	an	an	DET
biomedich-632	69	20	alpha	alpha	ADJ
biomedich-632	69	21	level	level	NOUN
biomedich-632	69	22	(	(	PUNCT
biomedich-632	69	23	α	α	NOUN
biomedich-632	69	24	)	)	PUNCT
biomedich-632	69	25	of	of	ADP
biomedich-632	69	26	0.05	0.05	NUM
biomedich-632	69	27	.	.	PUNCT
biomedich-632	70	1	results	result	NOUN
biomedich-632	70	2	are	be	AUX
biomedich-632	70	3	considered	consider	VERB
biomedich-632	70	4	significant	significant	ADJ
biomedich-632	70	5	if	if	SCONJ
biomedich-632	70	6	p<0.05	p<0.05	PROPN
biomedich-632	70	7	.	.	PUNCT
biomedich-632	71	1	this	this	DET
biomedich-632	71	2	analysis	analysis	NOUN
biomedich-632	71	3	uses	use	VERB
biomedich-632	71	4	statistical	statistical	ADJ
biomedich-632	71	5	package	package	NOUN
biomedich-632	71	6	for	for	ADP
biomedich-632	71	7	the	the	DET
biomedich-632	71	8	social	social	ADJ
biomedich-632	71	9	sciences	sciences	PROPN
biomedich-632	71	10	(	(	PUNCT
biomedich-632	71	11	spss	spss	PROPN
biomedich-632	71	12	)	)	PUNCT
biomedich-632	71	13	25.0.0	25.0.0	ADJ
biomedich-632	71	14	for	for	ADP
biomedich-632	71	15	windows	windows	PROPN
biomedich-632	71	16	software	software	NOUN
biomedich-632	71	17	.	.	PUNCT
biomedich-632	72	1	results	result	NOUN
biomedich-632	72	2	and	and	CCONJ
biomedich-632	72	3	discussion	discussion	NOUN
biomedich-632	72	4	result	result	VERB
biomedich-632	72	5	a	a	DET
biomedich-632	72	6	total	total	NOUN
biomedich-632	72	7	of	of	ADP
biomedich-632	72	8	33	33	NUM
biomedich-632	72	9	patients	patient	NOUN
biomedich-632	72	10	with	with	ADP
biomedich-632	72	11	primary	primary	ADJ
biomedich-632	72	12	crs	crs	PROPN
biomedich-632	72	13	and	and	CCONJ
biomedich-632	72	14	eight	eight	NUM
biomedich-632	72	15	subjects	subject	NOUN
biomedich-632	72	16	as	as	SCONJ
biomedich-632	72	17	control	control	NOUN
biomedich-632	72	18	were	be	AUX
biomedich-632	72	19	included	include	VERB
biomedich-632	72	20	in	in	ADP
biomedich-632	72	21	this	this	DET
biomedich-632	72	22	study	study	NOUN
biomedich-632	72	23	,	,	PUNCT
biomedich-632	72	24	with	with	ADP
biomedich-632	72	25	the	the	DET
biomedich-632	72	26	age	age	NOUN
biomedich-632	72	27	ranging	range	VERB
biomedich-632	72	28	from	from	ADP
biomedich-632	72	29	18	18	NUM
biomedich-632	72	30	to	to	PART
biomedich-632	72	31	68	68	NUM
biomedich-632	72	32	years	year	NOUN
biomedich-632	72	33	old	old	ADJ
biomedich-632	72	34	and	and	CCONJ
biomedich-632	72	35	a	a	DET
biomedich-632	72	36	mean	mean	ADJ
biomedich-632	72	37	age	age	NOUN
biomedich-632	72	38	of	of	ADP
biomedich-632	72	39	38,36	38,36	NUM
biomedich-632	72	40	±	±	NUM
biomedich-632	72	41	15,272	15,272	NUM
biomedich-632	72	42	years	year	NOUN
biomedich-632	72	43	.	.	PUNCT
biomedich-632	73	1	there	there	PRON
biomedich-632	73	2	were	be	VERB
biomedich-632	73	3	12	12	NUM
biomedich-632	73	4	males	male	NOUN
biomedich-632	73	5	and	and	CCONJ
biomedich-632	73	6	21	21	NUM
biomedich-632	73	7	females	female	NOUN
biomedich-632	73	8	.	.	PUNCT
biomedich-632	74	1	the	the	DET
biomedich-632	74	2	main	main	ADJ
biomedich-632	74	3	symptoms	symptom	NOUN
biomedich-632	74	4	observed	observe	VERB
biomedich-632	74	5	among	among	ADP
biomedich-632	74	6	the	the	DET
biomedich-632	74	7	patients	patient	NOUN
biomedich-632	74	8	were	be	AUX
biomedich-632	74	9	nasal	nasal	ADJ
biomedich-632	74	10	blockage	blockage	NOUN
biomedich-632	74	11	,	,	PUNCT
biomedich-632	74	12	nasal	nasal	ADJ
biomedich-632	74	13	discharge	discharge	NOUN
biomedich-632	74	14	,	,	PUNCT
biomedich-632	74	15	headache	headache	NOUN
biomedich-632	74	16	,	,	PUNCT
biomedich-632	74	17	facial	facial	ADJ
biomedich-632	74	18	pain	pain	NOUN
biomedich-632	74	19	,	,	PUNCT
biomedich-632	74	20	periorbital	periorbital	ADJ
biomedich-632	74	21	edema	edema	NOUN
biomedich-632	74	22	,	,	PUNCT
biomedich-632	74	23	and	and	CCONJ
biomedich-632	74	24	anosmia	anosmia	NOUN
biomedich-632	74	25	at	at	ADP
biomedich-632	74	26	54.5	54.5	NUM
biomedich-632	74	27	%	%	NOUN
biomedich-632	74	28	,	,	PUNCT
biomedich-632	74	29	24.2	24.2	NUM
biomedich-632	74	30	%	%	NOUN
biomedich-632	74	31	,	,	PUNCT
biomedich-632	74	32	12.1	12.1	NUM
biomedich-632	74	33	%	%	NOUN
biomedich-632	74	34	,	,	PUNCT
biomedich-632	74	35	6.1	6.1	NUM
biomedich-632	74	36	%	%	NOUN
biomedich-632	74	37	,	,	PUNCT
biomedich-632	74	38	3	3	NUM
biomedich-632	74	39	%	%	NOUN
biomedich-632	74	40	,	,	PUNCT
biomedich-632	74	41	and	and	CCONJ
biomedich-632	74	42	0	0	NUM
biomedich-632	74	43	%	%	NOUN
biomedich-632	74	44	.	.	PUNCT
biomedich-632	75	1	the	the	DET
biomedich-632	75	2	complaints	complaint	NOUN
biomedich-632	75	3	ranged	range	VERB
biomedich-632	75	4	from	from	ADP
biomedich-632	75	5	12	12	NUM
biomedich-632	75	6	to	to	PART
biomedich-632	75	7	416	416	NUM
biomedich-632	75	8	weeks	week	NOUN
biomedich-632	75	9	,	,	PUNCT
biomedich-632	75	10	with	with	ADP
biomedich-632	75	11	a	a	DET
biomedich-632	75	12	mean	mean	ADJ
biomedich-632	75	13	duration	duration	NOUN
biomedich-632	75	14	of	of	ADP
biomedich-632	75	15	handoko	handoko	PROPN
biomedich-632	75	16	et	et	PROPN
biomedich-632	75	17	al	al	PROPN
biomedich-632	75	18	.	.	PROPN
biomedich-632	76	1	–	–	PUNCT
biomedich-632	76	2	correlation	correlation	NOUN
biomedich-632	76	3	of	of	ADP
biomedich-632	76	4	bmp2	bmp2	NOUN
biomedich-632	76	5	with	with	ADP
biomedich-632	76	6	degree	degree	NOUN
biomedich-632	76	7	of	of	ADP
biomedich-632	76	8	osteitisin	osteitisin	NOUN
biomedich-632	76	9	primary	primary	ADJ
biomedich-632	76	10	crs	crs	PROPN
biomedich-632	76	11	…	…	PUNCT
biomedich-632	76	12	45	45	NUM
biomedich-632	76	13	91.21	91.21	NUM
biomedich-632	76	14	±	±	NUM
biomedich-632	76	15	109.99	109.99	NUM
biomedich-632	76	16	weeks	week	NOUN
biomedich-632	76	17	.	.	PUNCT
biomedich-632	77	1	bilateral	bilateral	ADJ
biomedich-632	77	2	paranasal	paranasal	ADJ
biomedich-632	77	3	sinus	sinus	NOUN
biomedich-632	77	4	involvement	involvement	NOUN
biomedich-632	77	5	was	be	AUX
biomedich-632	77	6	observed	observe	VERB
biomedich-632	77	7	in	in	ADP
biomedich-632	77	8	22	22	NUM
biomedich-632	77	9	samples	sample	NOUN
biomedich-632	77	10	(	(	PUNCT
biomedich-632	77	11	66.67	66.67	NUM
biomedich-632	77	12	%	%	NOUN
biomedich-632	77	13	)	)	PUNCT
biomedich-632	77	14	,	,	PUNCT
biomedich-632	77	15	while	while	SCONJ
biomedich-632	77	16	unilateral	unilateral	ADJ
biomedich-632	77	17	involvement	involvement	NOUN
biomedich-632	77	18	was	be	AUX
biomedich-632	77	19	observed	observe	VERB
biomedich-632	77	20	in	in	ADP
biomedich-632	77	21	11	11	NUM
biomedich-632	77	22	samples	sample	NOUN
biomedich-632	77	23	(	(	PUNCT
biomedich-632	77	24	33.33	33.33	NUM
biomedich-632	77	25	%	%	NOUN
biomedich-632	77	26	)	)	PUNCT
biomedich-632	77	27	.	.	PUNCT
biomedich-632	78	1	crs	crs	PROPN
biomedich-632	78	2	without	without	ADP
biomedich-632	78	3	polyps	polyp	NOUN
biomedich-632	78	4	was	be	AUX
biomedich-632	78	5	more	more	ADV
biomedich-632	78	6	prevalent	prevalent	ADJ
biomedich-632	78	7	,	,	PUNCT
biomedich-632	78	8	occurring	occur	VERB
biomedich-632	78	9	in	in	ADP
biomedich-632	78	10	17	17	NUM
biomedich-632	78	11	samples	sample	NOUN
biomedich-632	78	12	(	(	PUNCT
biomedich-632	78	13	51.52	51.52	NUM
biomedich-632	78	14	%	%	NOUN
biomedich-632	78	15	)	)	PUNCT
biomedich-632	78	16	,	,	PUNCT
biomedich-632	78	17	compared	compare	VERB
biomedich-632	78	18	to	to	ADP
biomedich-632	78	19	crs	crs	PROPN
biomedich-632	78	20	with	with	ADP
biomedich-632	78	21	polyps	polyp	NOUN
biomedich-632	78	22	.	.	PUNCT
biomedich-632	79	1	the	the	DET
biomedich-632	79	2	higher	high	ADJ
biomedich-632	79	3	incidence	incidence	NOUN
biomedich-632	79	4	of	of	ADP
biomedich-632	79	5	crs	crs	PROPN
biomedich-632	79	6	in	in	ADP
biomedich-632	79	7	females	female	NOUN
biomedich-632	79	8	can	can	AUX
biomedich-632	79	9	be	be	AUX
biomedich-632	79	10	attributed	attribute	VERB
biomedich-632	79	11	to	to	ADP
biomedich-632	79	12	anatomical	anatomical	ADJ
biomedich-632	79	13	and	and	CCONJ
biomedich-632	79	14	hormonal	hormonal	ADJ
biomedich-632	79	15	differences	difference	NOUN
biomedich-632	79	16	.	.	PUNCT
biomedich-632	80	1	females	female	NOUN
biomedich-632	80	2	typically	typically	ADV
biomedich-632	80	3	have	have	VERB
biomedich-632	80	4	smaller	small	ADJ
biomedich-632	80	5	sinus	sinus	NOUN
biomedich-632	80	6	ostia	ostia	NOUN
biomedich-632	80	7	than	than	ADP
biomedich-632	80	8	males	male	NOUN
biomedich-632	80	9	,	,	PUNCT
biomedich-632	80	10	which	which	PRON
biomedich-632	80	11	may	may	AUX
biomedich-632	80	12	impair	impair	VERB
biomedich-632	80	13	sinus	sinus	NOUN
biomedich-632	80	14	drainage	drainage	NOUN
biomedich-632	80	15	and	and	CCONJ
biomedich-632	80	16	contribute	contribute	VERB
biomedich-632	80	17	to	to	ADP
biomedich-632	80	18	crs	crs	PROPN
biomedich-632	80	19	development	development	NOUN
biomedich-632	80	20	.	.	PUNCT
biomedich-632	81	1	smaller	small	ADJ
biomedich-632	81	2	ostia	ostia	NOUN
biomedich-632	81	3	increase	increase	VERB
biomedich-632	81	4	the	the	DET
biomedich-632	81	5	likelihood	likelihood	NOUN
biomedich-632	81	6	of	of	ADP
biomedich-632	81	7	obstruction	obstruction	NOUN
biomedich-632	81	8	and	and	CCONJ
biomedich-632	81	9	bacterial	bacterial	ADJ
biomedich-632	81	10	colonization	colonization	NOUN
biomedich-632	81	11	in	in	ADP
biomedich-632	81	12	the	the	DET
biomedich-632	81	13	paranasal	paranasal	ADJ
biomedich-632	81	14	sinuses	sinus	NOUN
biomedich-632	81	15	.	.	PUNCT
biomedich-632	82	1	additionally	additionally	ADV
biomedich-632	82	2	,	,	PUNCT
biomedich-632	82	3	females	female	NOUN
biomedich-632	82	4	have	have	VERB
biomedich-632	82	5	significantly	significantly	ADV
biomedich-632	82	6	higher	high	ADJ
biomedich-632	82	7	levels	level	NOUN
biomedich-632	82	8	of	of	ADP
biomedich-632	82	9	estrogen	estrogen	NOUN
biomedich-632	82	10	compared	compare	VERB
biomedich-632	82	11	to	to	ADP
biomedich-632	82	12	males	male	NOUN
biomedich-632	82	13	,	,	PUNCT
biomedich-632	82	14	which	which	PRON
biomedich-632	82	15	may	may	AUX
biomedich-632	82	16	further	far	ADV
biomedich-632	82	17	influence	influence	VERB
biomedich-632	82	18	the	the	DET
biomedich-632	82	19	prevalence	prevalence	NOUN
biomedich-632	82	20	and	and	CCONJ
biomedich-632	82	21	pathophysiology	pathophysiology	NOUN
biomedich-632	82	22	of	of	ADP
biomedich-632	82	23	crs	crs	PROPN
biomedich-632	82	24	.	.	PUNCT
biomedich-632	83	1	ct	ct	PROPN
biomedich-632	83	2	scan	scan	NOUN
biomedich-632	83	3	of	of	ADP
biomedich-632	83	4	the	the	DET
biomedich-632	83	5	paranasal	paranasal	ADJ
biomedich-632	83	6	sinuses	sinus	NOUN
biomedich-632	83	7	was	be	AUX
biomedich-632	83	8	performed	perform	VERB
biomedich-632	83	9	using	use	VERB
biomedich-632	83	10	a	a	DET
biomedich-632	83	11	bone	bone	NOUN
biomedich-632	83	12	setting	set	VERB
biomedich-632	83	13	view	view	NOUN
biomedich-632	83	14	,	,	PUNCT
biomedich-632	83	15	with	with	ADP
biomedich-632	83	16	axial	axial	ADJ
biomedich-632	83	17	,	,	PUNCT
biomedich-632	83	18	coronal	coronal	NOUN
biomedich-632	83	19	,	,	PUNCT
biomedich-632	83	20	and	and	CCONJ
biomedich-632	83	21	parasagittal	parasagittal	ADJ
biomedich-632	83	22	slices	slice	NOUN
biomedich-632	83	23	of	of	ADP
biomedich-632	83	24	1	1	NUM
biomedich-632	83	25	-	-	SYM
biomedich-632	83	26	3	3	NUM
biomedich-632	83	27	mm	mm	NOUN
biomedich-632	83	28	thickness	thickness	NOUN
biomedich-632	83	29	,	,	PUNCT
biomedich-632	83	30	without	without	ADP
biomedich-632	83	31	contrast	contrast	NOUN
biomedich-632	83	32	(	(	PUNCT
biomedich-632	83	33	figure	figure	NOUN
biomedich-632	83	34	1	1	NUM
biomedich-632	83	35	)	)	PUNCT
biomedich-632	83	36	.	.	PUNCT
biomedich-632	84	1	osteitis	osteitis	NOUN
biomedich-632	84	2	assessment	assessment	NOUN
biomedich-632	84	3	was	be	AUX
biomedich-632	84	4	conducted	conduct	VERB
biomedich-632	84	5	on	on	ADP
biomedich-632	84	6	10	10	NUM
biomedich-632	84	7	sinuses	sinus	NOUN
biomedich-632	84	8	:	:	PUNCT
biomedich-632	84	9	left	leave	VERB
biomedich-632	84	10	and	and	CCONJ
biomedich-632	84	11	right	right	ADJ
biomedich-632	84	12	maxillary	maxillary	NOUN
biomedich-632	84	13	,	,	PUNCT
biomedich-632	84	14	left	leave	VERB
biomedich-632	84	15	and	and	CCONJ
biomedich-632	84	16	right	right	ADJ
biomedich-632	84	17	anterior	anterior	ADJ
biomedich-632	84	18	ethmoid	ethmoid	NOUN
biomedich-632	84	19	,	,	PUNCT
biomedich-632	84	20	left	leave	VERB
biomedich-632	84	21	and	and	CCONJ
biomedich-632	84	22	right	right	ADJ
biomedich-632	84	23	posterior	posterior	ADJ
biomedich-632	84	24	ethmoid	ethmoid	NOUN
biomedich-632	84	25	,	,	PUNCT
biomedich-632	84	26	left	leave	VERB
biomedich-632	84	27	and	and	CCONJ
biomedich-632	84	28	right	right	ADJ
biomedich-632	84	29	sphenoid	sphenoid	NOUN
biomedich-632	84	30	,	,	PUNCT
biomedich-632	84	31	and	and	CCONJ
biomedich-632	84	32	left	leave	VERB
biomedich-632	84	33	and	and	CCONJ
biomedich-632	84	34	right	right	ADJ
biomedich-632	84	35	frontal	frontal	ADJ
biomedich-632	84	36	sinuses	sinus	NOUN
biomedich-632	84	37	,	,	PUNCT
biomedich-632	84	38	using	use	VERB
biomedich-632	84	39	the	the	DET
biomedich-632	84	40	global	global	ADJ
biomedich-632	84	41	osteitis	osteitis	NOUN
biomedich-632	84	42	scoring	scoring	NOUN
biomedich-632	84	43	scale	scale	NOUN
biomedich-632	84	44	(	(	PUNCT
biomedich-632	84	45	goss	goss	PROPN
biomedich-632	84	46	)	)	PUNCT
biomedich-632	84	47	on	on	ADP
biomedich-632	84	48	axial	axial	ADJ
biomedich-632	84	49	,	,	PUNCT
biomedich-632	84	50	coronal	coronal	NOUN
biomedich-632	84	51	,	,	PUNCT
biomedich-632	84	52	and	and	CCONJ
biomedich-632	84	53	parasagittal	parasagittal	ADJ
biomedich-632	84	54	slices	slice	NOUN
biomedich-632	84	55	.	.	PUNCT
biomedich-632	85	1	the	the	DET
biomedich-632	85	2	lowest	low	ADJ
biomedich-632	85	3	total	total	ADJ
biomedich-632	85	4	goss	goss	PROPN
biomedich-632	85	5	score	score	NOUN
biomedich-632	85	6	was	be	AUX
biomedich-632	85	7	0	0	NUM
biomedich-632	85	8	,	,	PUNCT
biomedich-632	85	9	and	and	CCONJ
biomedich-632	85	10	the	the	DET
biomedich-632	85	11	highest	high	ADJ
biomedich-632	85	12	total	total	ADJ
biomedich-632	85	13	score	score	NOUN
biomedich-632	85	14	was	be	AUX
biomedich-632	85	15	50	50	NUM
biomedich-632	85	16	.	.	PUNCT
biomedich-632	86	1	a	a	DET
biomedich-632	86	2	higher	high	ADJ
biomedich-632	86	3	goss	goss	PROPN
biomedich-632	86	4	score	score	NOUN
biomedich-632	86	5	indicates	indicate	VERB
biomedich-632	86	6	more	more	ADV
biomedich-632	86	7	severe	severe	ADJ
biomedich-632	86	8	osteitis	osteitis	NOUN
biomedich-632	86	9	.	.	PUNCT
biomedich-632	87	1	goss	goss	PROPN
biomedich-632	87	2	scores	score	NOUN
biomedich-632	87	3	were	be	AUX
biomedich-632	87	4	then	then	ADV
biomedich-632	87	5	categorized	categorize	VERB
biomedich-632	87	6	into	into	ADP
biomedich-632	87	7	four	four	NUM
biomedich-632	87	8	degrees	degree	NOUN
biomedich-632	87	9	:	:	PUNCT
biomedich-632	87	10	no	no	DET
biomedich-632	87	11	osteitis	osteitis	NOUN
biomedich-632	87	12	(	(	PUNCT
biomedich-632	87	13	goss	goss	PROPN
biomedich-632	87	14	score	score	VERB
biomedich-632	87	15	<	<	PROPN
biomedich-632	87	16	5	5	NUM
biomedich-632	87	17	)	)	PUNCT
biomedich-632	87	18	,	,	PUNCT
biomedich-632	87	19	mild	mild	ADJ
biomedich-632	87	20	osteitis	osteitis	NOUN
biomedich-632	87	21	(	(	PUNCT
biomedich-632	87	22	goss	goss	PROPN
biomedich-632	87	23	score	score	VERB
biomedich-632	87	24	5	5	NUM
biomedich-632	87	25	-	-	SYM
biomedich-632	87	26	20	20	NUM
biomedich-632	87	27	)	)	PUNCT
biomedich-632	87	28	,	,	PUNCT
biomedich-632	87	29	moderate	moderate	ADJ
biomedich-632	87	30	osteitis	osteitis	PROPN
biomedich-632	87	31	(	(	PUNCT
biomedich-632	87	32	goss	goss	PROPN
biomedich-632	87	33	score	score	VERB
biomedich-632	87	34	20	20	NUM
biomedich-632	87	35	-	-	SYM
biomedich-632	87	36	35	35	NUM
biomedich-632	87	37	)	)	PUNCT
biomedich-632	87	38	,	,	PUNCT
biomedich-632	87	39	and	and	CCONJ
biomedich-632	87	40	severe	severe	ADJ
biomedich-632	87	41	osteitis	osteitis	NOUN
biomedich-632	87	42	(	(	PUNCT
biomedich-632	87	43	goss	goss	PROPN
biomedich-632	87	44	score	score	PROPN
biomedich-632	87	45	>	>	PROPN
biomedich-632	87	46	35	35	NUM
biomedich-632	87	47	)	)	PUNCT
biomedich-632	87	48	.	.	PUNCT
biomedich-632	88	1	osteitis	osteitis	NOUN
biomedich-632	88	2	on	on	ADP
biomedich-632	88	3	ct	ct	PROPN
biomedich-632	88	4	scan	scan	PROPN
biomedich-632	88	5	was	be	AUX
biomedich-632	88	6	characterized	characterize	VERB
biomedich-632	88	7	by	by	ADP
biomedich-632	88	8	loss	loss	NOUN
biomedich-632	88	9	of	of	ADP
biomedich-632	88	10	bone	bone	NOUN
biomedich-632	88	11	definition	definition	NOUN
biomedich-632	88	12	,	,	PUNCT
biomedich-632	88	13	hyperostosis	hyperostosis	NOUN
biomedich-632	88	14	,	,	PUNCT
biomedich-632	88	15	new	new	ADJ
biomedich-632	88	16	bone	bone	NOUN
biomedich-632	88	17	formation	formation	NOUN
biomedich-632	88	18	,	,	PUNCT
biomedich-632	88	19	or	or	CCONJ
biomedich-632	88	20	signs	sign	NOUN
biomedich-632	88	21	of	of	ADP
biomedich-632	88	22	heterogeneity	heterogeneity	NOUN
biomedich-632	88	23	in	in	ADP
biomedich-632	88	24	the	the	DET
biomedich-632	88	25	walls	wall	NOUN
biomedich-632	88	26	of	of	ADP
biomedich-632	88	27	the	the	DET
biomedich-632	88	28	paranasal	paranasal	ADJ
biomedich-632	88	29	sinuses	sinus	NOUN
biomedich-632	88	30	.	.	PUNCT
biomedich-632	89	1	figure	figure	NOUN
biomedich-632	89	2	1	1	NUM
biomedich-632	89	3	.	.	PUNCT
biomedich-632	89	4	ct	ct	PROPN
biomedich-632	89	5	scan	scan	PROPN
biomedich-632	89	6	image	image	NOUN
biomedich-632	89	7	of	of	ADP
biomedich-632	89	8	osteitis	osteitis	NOUN
biomedich-632	89	9	in	in	ADP
biomedich-632	89	10	various	various	ADJ
biomedich-632	89	11	sections	section	NOUN
biomedich-632	89	12	.	.	PUNCT
biomedich-632	90	1	the	the	DET
biomedich-632	90	2	appearance	appearance	NOUN
biomedich-632	90	3	of	of	ADP
biomedich-632	90	4	osteitis	osteitis	NOUN
biomedich-632	90	5	(	(	PUNCT
biomedich-632	90	6	loss	loss	NOUN
biomedich-632	90	7	of	of	ADP
biomedich-632	90	8	bone	bone	NOUN
biomedich-632	90	9	definition	definition	NOUN
biomedich-632	90	10	,	,	PUNCT
biomedich-632	90	11	hyperostosis	hyperostosis	NOUN
biomedich-632	90	12	,	,	PUNCT
biomedich-632	90	13	new	new	ADJ
biomedich-632	90	14	bone	bone	NOUN
biomedich-632	90	15	formation	formation	NOUN
biomedich-632	90	16	,	,	PUNCT
biomedich-632	90	17	or	or	CCONJ
biomedich-632	90	18	signs	sign	NOUN
biomedich-632	90	19	of	of	ADP
biomedich-632	90	20	heterogeneity	heterogeneity	NOUN
biomedich-632	90	21	)	)	PUNCT
biomedich-632	90	22	on	on	ADP
biomedich-632	90	23	ct	ct	PROPN
biomedich-632	90	24	scan	scan	ADJ
biomedich-632	90	25	samples	sample	NOUN
biomedich-632	90	26	from	from	ADP
biomedich-632	90	27	crs	crs	PROPN
biomedich-632	90	28	patients	patient	NOUN
biomedich-632	90	29	with	with	ADP
biomedich-632	90	30	osteitis	osteitis	NOUN
biomedich-632	90	31	is	be	AUX
biomedich-632	90	32	indicated	indicate	VERB
biomedich-632	90	33	by	by	ADP
biomedich-632	90	34	white	white	ADJ
biomedich-632	90	35	arrows	arrow	NOUN
biomedich-632	90	36	.	.	PUNCT
biomedich-632	91	1	a	a	DET
biomedich-632	91	2	-	-	PUNCT
biomedich-632	91	3	b	b	NOUN
biomedich-632	91	4	axial	axial	ADJ
biomedich-632	91	5	sections	section	NOUN
biomedich-632	91	6	of	of	ADP
biomedich-632	91	7	the	the	DET
biomedich-632	91	8	maxillary	maxillary	NOUN
biomedich-632	91	9	sinus	sinus	NOUN
biomedich-632	91	10	:	:	PUNCT
biomedich-632	91	11	a	a	DET
biomedich-632	91	12	goss	goss	PROPN
biomedich-632	91	13	0/0	0/0	PROPN
biomedich-632	91	14	.	.	PUNCT
biomedich-632	92	1	b	b	PROPN
biomedich-632	92	2	goss	goss	PROPN
biomedich-632	92	3	5/5	5/5	NUM
biomedich-632	92	4	.	.	PUNCT
biomedich-632	93	1	c	c	X
biomedich-632	93	2	-	-	PUNCT
biomedich-632	93	3	d	d	PROPN
biomedich-632	93	4	coronal	coronal	ADJ
biomedich-632	93	5	sections	section	NOUN
biomedich-632	93	6	of	of	ADP
biomedich-632	93	7	the	the	DET
biomedich-632	93	8	maxillary	maxillary	NOUN
biomedich-632	93	9	sinus	sinus	NOUN
biomedich-632	93	10	.	.	PUNCT
biomedich-632	94	1	in	in	ADP
biomedich-632	94	2	evaluating	evaluate	VERB
biomedich-632	94	3	330	330	NUM
biomedich-632	94	4	paranasal	paranasal	ADJ
biomedich-632	94	5	sinuses	sinus	NOUN
biomedich-632	94	6	,	,	PUNCT
biomedich-632	94	7	osteitis	osteitis	NOUN
biomedich-632	94	8	was	be	AUX
biomedich-632	94	9	detected	detect	VERB
biomedich-632	94	10	in	in	ADP
biomedich-632	94	11	168	168	NUM
biomedich-632	94	12	cases	case	NOUN
biomedich-632	94	13	(	(	PUNCT
biomedich-632	94	14	50.9	50.9	NUM
biomedich-632	94	15	%	%	NOUN
biomedich-632	94	16	)	)	PUNCT
biomedich-632	94	17	.	.	PUNCT
biomedich-632	95	1	the	the	DET
biomedich-632	95	2	anterior	anterior	ADJ
biomedich-632	95	3	ethmoid	ethmoid	NOUN
biomedich-632	95	4	sinuses	sinus	NOUN
biomedich-632	95	5	were	be	AUX
biomedich-632	95	6	the	the	DET
biomedich-632	95	7	most	most	ADV
biomedich-632	95	8	frequently	frequently	ADV
biomedich-632	95	9	affected	affect	VERB
biomedich-632	95	10	,	,	PUNCT
biomedich-632	95	11	accounting	account	VERB
biomedich-632	95	12	for	for	ADP
biomedich-632	95	13	50	50	NUM
biomedich-632	95	14	cases	case	NOUN
biomedich-632	95	15	(	(	PUNCT
biomedich-632	95	16	29.8	29.8	NUM
biomedich-632	95	17	%	%	NOUN
biomedich-632	95	18	)	)	PUNCT
biomedich-632	95	19	,	,	PUNCT
biomedich-632	95	20	while	while	SCONJ
biomedich-632	95	21	the	the	DET
biomedich-632	95	22	frontal	frontal	ADJ
biomedich-632	95	23	sinuses	sinus	NOUN
biomedich-632	95	24	exhibited	exhibit	VERB
biomedich-632	95	25	the	the	DET
biomedich-632	95	26	lowest	low	ADJ
biomedich-632	95	27	incidence	incidence	NOUN
biomedich-632	95	28	,	,	PUNCT
biomedich-632	95	29	with	with	ADP
biomedich-632	95	30	17	17	NUM
biomedich-632	95	31	cases	case	NOUN
biomedich-632	95	32	(	(	PUNCT
biomedich-632	95	33	10.1	10.1	NUM
biomedich-632	95	34	%	%	NOUN
biomedich-632	95	35	)	)	PUNCT
biomedich-632	95	36	.	.	PUNCT
biomedich-632	96	1	the	the	DET
biomedich-632	96	2	efficacy	efficacy	NOUN
biomedich-632	96	3	of	of	ADP
biomedich-632	96	4	osteitis	osteitis	NOUN
biomedich-632	96	5	detection	detection	NOUN
biomedich-632	96	6	was	be	AUX
biomedich-632	96	7	influenced	influence	VERB
biomedich-632	96	8	by	by	ADP
biomedich-632	96	9	the	the	DET
biomedich-632	96	10	type	type	NOUN
biomedich-632	96	11	of	of	ADP
biomedich-632	96	12	ct	ct	NUM
biomedich-632	96	13	scan	scan	PROPN
biomedich-632	96	14	slice	slice	PROPN
biomedich-632	96	15	.	.	PUNCT
biomedich-632	97	1	axial	axial	ADJ
biomedich-632	97	2	slices	slice	NOUN
biomedich-632	97	3	proved	prove	VERB
biomedich-632	97	4	to	to	PART
biomedich-632	97	5	be	be	AUX
biomedich-632	97	6	the	the	DET
biomedich-632	97	7	most	most	ADV
biomedich-632	97	8	effective	effective	ADJ
biomedich-632	97	9	,	,	PUNCT
biomedich-632	97	10	identifying	identify	VERB
biomedich-632	97	11	osteitis	osteitis	NOUN
biomedich-632	97	12	in	in	ADP
biomedich-632	97	13	80	80	NUM
biomedich-632	97	14	%	%	NOUN
biomedich-632	97	15	of	of	ADP
biomedich-632	97	16	the	the	DET
biomedich-632	97	17	cases	case	NOUN
biomedich-632	97	18	involving	involve	VERB
biomedich-632	97	19	the	the	DET
biomedich-632	97	20	maxillary	maxillary	NOUN
biomedich-632	97	21	sinuses	sinus	NOUN
biomedich-632	97	22	,	,	PUNCT
biomedich-632	97	23	corresponding	correspond	VERB
biomedich-632	97	24	to	to	ADP
biomedich-632	97	25	36	36	NUM
biomedich-632	97	26	pairs	pair	NOUN
biomedich-632	97	27	.	.	PUNCT
biomedich-632	98	1	conversely	conversely	ADV
biomedich-632	98	2	,	,	PUNCT
biomedich-632	98	3	coronal	coronal	ADJ
biomedich-632	98	4	slices	slice	NOUN
biomedich-632	98	5	demonstrated	demonstrate	VERB
biomedich-632	98	6	lower	low	ADJ
biomedich-632	98	7	accuracy	accuracy	NOUN
biomedich-632	98	8	for	for	ADP
biomedich-632	98	9	osteitis	osteitis	NOUN
biomedich-632	98	10	detection	detection	NOUN
biomedich-632	98	11	in	in	ADP
biomedich-632	98	12	the	the	DET
biomedich-632	98	13	paranasal	paranasal	ADJ
biomedich-632	98	14	sinuses	sinus	NOUN
biomedich-632	98	15	,	,	PUNCT
biomedich-632	98	16	excep	excep	VERB
biomedich-632	98	17	the	the	DET
biomedich-632	98	18	sphenoid	sphenoid	NOUN
biomedich-632	98	19	sinuses	sinus	NOUN
biomedich-632	98	20	,	,	PUNCT
biomedich-632	98	21	where	where	SCONJ
biomedich-632	98	22	18	18	NUM
biomedich-632	98	23	cases	case	NOUN
biomedich-632	98	24	(	(	PUNCT
biomedich-632	98	25	10.7	10.7	NUM
biomedich-632	98	26	%	%	NOUN
biomedich-632	98	27	)	)	PUNCT
biomedich-632	98	28	were	be	AUX
biomedich-632	98	29	accurately	accurately	ADV
biomedich-632	98	30	detected	detect	VERB
biomedich-632	98	31	using	use	VERB
biomedich-632	98	32	coronal	coronal	ADJ
biomedich-632	98	33	slices	slice	NOUN
biomedich-632	98	34	(	(	PUNCT
biomedich-632	98	35	figure	figure	NOUN
biomedich-632	98	36	2	2	NUM
biomedich-632	98	37	)	)	PUNCT
biomedich-632	98	38	.	.	PUNCT
biomedich-632	99	1	b	b	X
biomedich-632	100	1	c	c	NOUN
biomedich-632	100	2	d	d	X
biomedich-632	100	3	a	a	DET
biomedich-632	100	4	46	46	NUM
biomedich-632	100	5	biology	biology	NOUN
biomedich-632	100	6	,	,	PUNCT
biomedich-632	100	7	medicine	medicine	NOUN
biomedich-632	100	8	,	,	PUNCT
biomedich-632	100	9	&	&	CCONJ
biomedich-632	100	10	natural	natural	ADJ
biomedich-632	100	11	product	product	NOUN
biomedich-632	100	12	chemistry	chemistry	NOUN
biomedich-632	100	13	14	14	NUM
biomedich-632	100	14	(	(	PUNCT
biomedich-632	100	15	1	1	NUM
biomedich-632	100	16	)	)	PUNCT
biomedich-632	100	17	,	,	PUNCT
biomedich-632	100	18	2025	2025	NUM
biomedich-632	100	19	:	:	PUNCT
biomedich-632	100	20	43	43	NUM
biomedich-632	100	21	-	-	SYM
biomedich-632	100	22	50	50	NUM
biomedich-632	100	23	36	36	NUM
biomedich-632	100	24	48	48	NUM
biomedich-632	100	25	32	32	NUM
biomedich-632	100	26	5	5	NUM
biomedich-632	100	27	8	8	NUM
biomedich-632	100	28	6	6	NUM
biomedich-632	100	29	2	2	NUM
biomedich-632	100	30	1	1	NUM
biomedich-632	100	31	18	18	NUM
biomedich-632	100	32	7	7	NUM
biomedich-632	100	33	3	3	NUM
biomedich-632	100	34	2	2	NUM
biomedich-632	100	35	0	0	NUM
biomedich-632	100	36	10	10	NUM
biomedich-632	100	37	20	20	NUM
biomedich-632	100	38	30	30	NUM
biomedich-632	100	39	40	40	NUM
biomedich-632	100	40	50	50	NUM
biomedich-632	100	41	60	60	NUM
biomedich-632	100	42	maksilaris	maksilaris	NOUN
biomedich-632	100	43	d	d	NOUN
biomedich-632	100	44	/	/	SYM
biomedich-632	100	45	s	s	PART
biomedich-632	100	46	ethmoidalis	ethmoidali	NOUN
biomedich-632	100	47	anterior	anterior	ADJ
biomedich-632	100	48	d	d	PROPN
biomedich-632	100	49	/	/	SYM
biomedich-632	100	50	s	s	X
biomedich-632	100	51	ethmoidalis	ethmoidali	NOUN
biomedich-632	100	52	posterior	posterior	ADJ
biomedich-632	100	53	d	d	PROPN
biomedich-632	100	54	/	/	SYM
biomedich-632	100	55	s	s	AUX
biomedich-632	100	56	sphenoidalis	sphenoidalis	X
biomedich-632	100	57	d	d	NOUN
biomedich-632	100	58	/	/	SYM
biomedich-632	100	59	s	s	NOUN
biomedich-632	100	60	frontalis	frontalis	NOUN
biomedich-632	100	61	d	d	PROPN
biomedich-632	100	62	/	/	SYM
biomedich-632	100	63	s	s	PART
biomedich-632	100	64	osteitis	osteitis	NOUN
biomedich-632	100	65	detected	detect	VERB
biomedich-632	100	66	on	on	ADP
biomedich-632	100	67	ct	ct	PROPN
biomedich-632	100	68	scan	scan	PROPN
biomedich-632	100	69	sections	section	NOUN
biomedich-632	100	70	(	(	PUNCT
biomedich-632	100	71	n=168	n=168	NOUN
biomedich-632	100	72	)	)	PUNCT
biomedich-632	100	73	aksial	aksial	ADJ
biomedich-632	100	74	koronal	koronal	ADJ
biomedich-632	100	75	parasagital	parasagital	ADJ
biomedich-632	100	76	figure	figure	NOUN
biomedich-632	100	77	2	2	NUM
biomedich-632	100	78	.	.	PUNCT
biomedich-632	101	1	distribution	distribution	NOUN
biomedich-632	101	2	of	of	ADP
biomedich-632	101	3	osteitis	osteitis	NOUN
biomedich-632	101	4	detected	detect	VERB
biomedich-632	101	5	in	in	ADP
biomedich-632	101	6	ct	ct	PROPN
biomedich-632	101	7	scan	scan	ADJ
biomedich-632	101	8	slices	slice	NOUN
biomedich-632	101	9	of	of	ADP
biomedich-632	101	10	crs	crs	NOUN
biomedich-632	101	11	patients	patient	NOUN
biomedich-632	101	12	.	.	PUNCT
biomedich-632	102	1	blue	blue	ADJ
biomedich-632	102	2	bars	bar	NOUN
biomedich-632	102	3	denote	denote	VERB
biomedich-632	102	4	the	the	DET
biomedich-632	102	5	prevalence	prevalence	NOUN
biomedich-632	102	6	of	of	ADP
biomedich-632	102	7	osteitis	osteitis	NOUN
biomedich-632	102	8	in	in	ADP
biomedich-632	102	9	the	the	DET
biomedich-632	102	10	paranasal	paranasal	ADJ
biomedich-632	102	11	sinuses	sinus	NOUN
biomedich-632	102	12	detected	detect	VERB
biomedich-632	102	13	on	on	ADP
biomedich-632	102	14	axial	axial	ADJ
biomedich-632	102	15	ct	ct	PROPN
biomedich-632	102	16	scan	scan	PROPN
biomedich-632	102	17	slices	slice	NOUN
biomedich-632	102	18	.	.	PUNCT
biomedich-632	103	1	orange	orange	PROPN
biomedich-632	103	2	bars	bar	NOUN
biomedich-632	103	3	represent	represent	VERB
biomedich-632	103	4	coronal	coronal	ADJ
biomedich-632	103	5	slices	slice	NOUN
biomedich-632	103	6	,	,	PUNCT
biomedich-632	103	7	while	while	SCONJ
biomedich-632	103	8	gray	gray	ADJ
biomedich-632	103	9	bars	bar	NOUN
biomedich-632	103	10	correspond	correspond	VERB
biomedich-632	103	11	to	to	ADP
biomedich-632	103	12	parasagittal	parasagittal	ADJ
biomedich-632	103	13	slices	slice	NOUN
biomedich-632	103	14	.	.	PUNCT
biomedich-632	104	1	figure	figure	NOUN
biomedich-632	104	2	3	3	NUM
biomedich-632	104	3	illustrates	illustrate	VERB
biomedich-632	104	4	the	the	DET
biomedich-632	104	5	distribution	distribution	NOUN
biomedich-632	104	6	of	of	ADP
biomedich-632	104	7	osteitis	osteitis	NOUN
biomedich-632	104	8	severity	severity	NOUN
biomedich-632	104	9	within	within	ADP
biomedich-632	104	10	the	the	DET
biomedich-632	104	11	rsk	rsk	PROPN
biomedich-632	104	12	sample	sample	NOUN
biomedich-632	104	13	,	,	PUNCT
biomedich-632	104	14	indicating	indicate	VERB
biomedich-632	104	15	a	a	DET
biomedich-632	104	16	predominance	predominance	NOUN
biomedich-632	104	17	of	of	ADP
biomedich-632	104	18	mild	mild	ADJ
biomedich-632	104	19	osteitis	osteitis	NOUN
biomedich-632	104	20	cases	case	NOUN
biomedich-632	104	21	(	(	PUNCT
biomedich-632	104	22	51.52	51.52	NUM
biomedich-632	104	23	%	%	NOUN
biomedich-632	104	24	)	)	PUNCT
biomedich-632	104	25	.	.	PUNCT
biomedich-632	105	1	among	among	ADP
biomedich-632	105	2	these	these	DET
biomedich-632	105	3	mild	mild	ADJ
biomedich-632	105	4	osteitis	osteitis	NOUN
biomedich-632	105	5	cases	case	NOUN
biomedich-632	105	6	,	,	PUNCT
biomedich-632	105	7	seven	seven	NUM
biomedich-632	105	8	patients	patient	NOUN
biomedich-632	105	9	had	have	VERB
biomedich-632	105	10	nasal	nasal	ADJ
biomedich-632	105	11	polyps	polyp	NOUN
biomedich-632	105	12	,	,	PUNCT
biomedich-632	105	13	while	while	SCONJ
biomedich-632	105	14	eight	eight	NUM
biomedich-632	105	15	patients	patient	NOUN
biomedich-632	105	16	did	do	VERB
biomedich-632	105	17	not	not	PART
biomedich-632	105	18	.	.	PUNCT
biomedich-632	106	1	for	for	ADP
biomedich-632	106	2	moderate	moderate	ADJ
biomedich-632	106	3	osteitis	osteitis	NOUN
biomedich-632	106	4	(	(	PUNCT
biomedich-632	106	5	30.30	30.30	NUM
biomedich-632	106	6	%	%	NOUN
biomedich-632	106	7	)	)	PUNCT
biomedich-632	106	8	,	,	PUNCT
biomedich-632	106	9	nine	nine	NUM
biomedich-632	106	10	patients	patient	NOUN
biomedich-632	106	11	were	be	AUX
biomedich-632	106	12	diagnosed	diagnose	VERB
biomedich-632	106	13	with	with	ADP
biomedich-632	106	14	nasal	nasal	ADJ
biomedich-632	106	15	polyps	polyp	NOUN
biomedich-632	106	16	,	,	PUNCT
biomedich-632	106	17	and	and	CCONJ
biomedich-632	106	18	two	two	NUM
biomedich-632	106	19	patients	patient	NOUN
biomedich-632	106	20	were	be	AUX
biomedich-632	106	21	without	without	ADP
biomedich-632	106	22	nasal	nasal	ADJ
biomedich-632	106	23	polyps	polyp	NOUN
biomedich-632	106	24	.	.	PUNCT
biomedich-632	107	1	in	in	ADP
biomedich-632	107	2	cases	case	NOUN
biomedich-632	107	3	of	of	ADP
biomedich-632	107	4	severe	severe	ADJ
biomedich-632	107	5	osteitis	osteitis	NOUN
biomedich-632	107	6	(	(	PUNCT
biomedich-632	107	7	3.03	3.03	NUM
biomedich-632	107	8	%	%	NOUN
biomedich-632	107	9	)	)	PUNCT
biomedich-632	107	10	,	,	PUNCT
biomedich-632	107	11	all	all	DET
biomedich-632	107	12	patients	patient	NOUN
biomedich-632	107	13	had	have	VERB
biomedich-632	107	14	nasal	nasal	ADJ
biomedich-632	107	15	polyps	polyp	NOUN
biomedich-632	107	16	.	.	PUNCT
biomedich-632	108	1	additionally	additionally	ADV
biomedich-632	108	2	,	,	PUNCT
biomedich-632	108	3	15.15	15.15	NUM
biomedich-632	108	4	%	%	NOUN
biomedich-632	108	5	of	of	ADP
biomedich-632	108	6	the	the	DET
biomedich-632	108	7	rsk	rsk	PROPN
biomedich-632	108	8	sample	sample	NOUN
biomedich-632	108	9	had	have	VERB
biomedich-632	108	10	no	no	DET
biomedich-632	108	11	osteitis	osteitis	NOUN
biomedich-632	108	12	.	.	PUNCT
biomedich-632	109	1	figure	figure	NOUN
biomedich-632	109	2	3	3	NUM
biomedich-632	109	3	.	.	PUNCT
biomedich-632	110	1	distribution	distribution	NOUN
biomedich-632	110	2	of	of	ADP
biomedich-632	110	3	osteitis	osteitis	NOUN
biomedich-632	110	4	severity	severity	NOUN
biomedich-632	110	5	in	in	ADP
biomedich-632	110	6	crs	crs	NOUN
biomedich-632	110	7	patients	patient	NOUN
biomedich-632	110	8	as	as	SCONJ
biomedich-632	110	9	measured	measure	VERB
biomedich-632	110	10	with	with	ADP
biomedich-632	110	11	goss	goss	PROPN
biomedich-632	110	12	.	.	PUNCT
biomedich-632	111	1	in	in	ADP
biomedich-632	111	2	this	this	DET
biomedich-632	111	3	study	study	NOUN
biomedich-632	111	4	,	,	PUNCT
biomedich-632	111	5	a	a	DET
biomedich-632	111	6	total	total	NOUN
biomedich-632	111	7	of	of	ADP
biomedich-632	111	8	17	17	NUM
biomedich-632	111	9	chronic	chronic	ADJ
biomedich-632	111	10	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	111	11	samples	sample	NOUN
biomedich-632	111	12	with	with	ADP
biomedich-632	111	13	polyps	polyp	NOUN
biomedich-632	111	14	and	and	CCONJ
biomedich-632	111	15	16	16	NUM
biomedich-632	111	16	samples	sample	NOUN
biomedich-632	111	17	without	without	ADP
biomedich-632	111	18	polyps	polyp	NOUN
biomedich-632	111	19	were	be	AUX
biomedich-632	111	20	analyzed	analyze	VERB
biomedich-632	111	21	.	.	PUNCT
biomedich-632	112	1	the	the	DET
biomedich-632	112	2	mean	mean	ADJ
biomedich-632	112	3	concentration	concentration	NOUN
biomedich-632	112	4	of	of	ADP
biomedich-632	112	5	bmp2	bmp2	NOUN
biomedich-632	112	6	in	in	ADP
biomedich-632	112	7	chronic	chronic	ADJ
biomedich-632	112	8	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	112	9	samples	sample	NOUN
biomedich-632	112	10	with	with	ADP
biomedich-632	112	11	polyps	polyp	NOUN
biomedich-632	112	12	was	be	AUX
biomedich-632	112	13	3.78	3.78	NUM
biomedich-632	112	14	,	,	PUNCT
biomedich-632	112	15	with	with	ADP
biomedich-632	112	16	a	a	DET
biomedich-632	112	17	standard	standard	ADJ
biomedich-632	112	18	deviation	deviation	NOUN
biomedich-632	112	19	of	of	ADP
biomedich-632	112	20	5.43	5.43	NUM
biomedich-632	112	21	.	.	PUNCT
biomedich-632	113	1	in	in	ADP
biomedich-632	113	2	contrast	contrast	NOUN
biomedich-632	113	3	,	,	PUNCT
biomedich-632	113	4	the	the	DET
biomedich-632	113	5	mean	mean	ADJ
biomedich-632	113	6	bmp2	bmp2	ADJ
biomedich-632	113	7	concentration	concentration	NOUN
biomedich-632	113	8	in	in	ADP
biomedich-632	113	9	samples	sample	NOUN
biomedich-632	113	10	without	without	ADP
biomedich-632	113	11	polyps	polyp	NOUN
biomedich-632	113	12	was	be	AUX
biomedich-632	113	13	1.30	1.30	NUM
biomedich-632	113	14	,	,	PUNCT
biomedich-632	113	15	with	with	ADP
biomedich-632	113	16	a	a	DET
biomedich-632	113	17	standard	standard	ADJ
biomedich-632	113	18	deviation	deviation	NOUN
biomedich-632	113	19	5.43	5.43	NUM
biomedich-632	113	20	(	(	PUNCT
biomedich-632	113	21	table	table	NOUN
biomedich-632	113	22	1	1	NUM
biomedich-632	113	23	)	)	PUNCT
biomedich-632	113	24	.	.	PUNCT
biomedich-632	114	1	this	this	PRON
biomedich-632	114	2	indicates	indicate	VERB
biomedich-632	114	3	that	that	SCONJ
biomedich-632	114	4	bmp2	bmp2	ADJ
biomedich-632	114	5	levels	level	NOUN
biomedich-632	114	6	are	be	AUX
biomedich-632	114	7	higher	high	ADJ
biomedich-632	114	8	in	in	ADP
biomedich-632	114	9	chronic	chronic	ADJ
biomedich-632	114	10	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	114	11	with	with	ADP
biomedich-632	114	12	polyps	polyp	NOUN
biomedich-632	114	13	than	than	ADP
biomedich-632	114	14	those	those	PRON
biomedich-632	114	15	without	without	ADP
biomedich-632	114	16	.	.	PUNCT
biomedich-632	115	1	comparison	comparison	NOUN
biomedich-632	115	2	analysis	analysis	NOUN
biomedich-632	115	3	using	use	VERB
biomedich-632	115	4	the	the	DET
biomedich-632	115	5	mann	mann	PROPN
biomedich-632	115	6	-	-	PUNCT
biomedich-632	115	7	whitney	whitney	PROPN
biomedich-632	115	8	test	test	NOUN
biomedich-632	115	9	,	,	PUNCT
biomedich-632	115	10	with	with	ADP
biomedich-632	115	11	significance	significance	NOUN
biomedich-632	115	12	set	set	VERB
biomedich-632	115	13	at	at	ADP
biomedich-632	115	14	p<0.05	p<0.05	NOUN
biomedich-632	115	15	,	,	PUNCT
biomedich-632	115	16	yielded	yield	VERB
biomedich-632	115	17	a	a	DET
biomedich-632	115	18	p	p	NOUN
biomedich-632	115	19	-	-	PUNCT
biomedich-632	115	20	value	value	NOUN
biomedich-632	115	21	of	of	ADP
biomedich-632	115	22	0.037	0.037	NUM
biomedich-632	115	23	for	for	ADP
biomedich-632	115	24	bmp2	bmp2	ADJ
biomedich-632	115	25	concentrations	concentration	NOUN
biomedich-632	115	26	between	between	ADP
biomedich-632	115	27	chronic	chronic	ADJ
biomedich-632	115	28	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	115	29	with	with	ADP
biomedich-632	115	30	and	and	CCONJ
biomedich-632	115	31	without	without	ADP
biomedich-632	115	32	polyps	polyp	NOUN
biomedich-632	115	33	.	.	PUNCT
biomedich-632	116	1	this	this	DET
biomedich-632	116	2	result	result	NOUN
biomedich-632	116	3	indicates	indicate	VERB
biomedich-632	116	4	a	a	DET
biomedich-632	116	5	significant	significant	ADJ
biomedich-632	116	6	difference	difference	NOUN
biomedich-632	116	7	,	,	PUNCT
biomedich-632	116	8	demonstrating	demonstrate	VERB
biomedich-632	116	9	an	an	DET
biomedich-632	116	10	0	0	NUM
biomedich-632	116	11	1	1	NUM
biomedich-632	116	12	2	2	NUM
biomedich-632	116	13	3	3	NUM
biomedich-632	116	14	4	4	NUM
biomedich-632	116	15	5	5	NUM
biomedich-632	116	16	6	6	NUM
biomedich-632	116	17	7	7	NUM
biomedich-632	116	18	8	8	NUM
biomedich-632	116	19	9	9	NUM
biomedich-632	116	20	10	10	NUM
biomedich-632	116	21	no	no	DET
biomedich-632	116	22	osteitis	osteitis	NOUN
biomedich-632	116	23	mild	mild	ADJ
biomedich-632	116	24	degree	degree	NOUN
biomedich-632	116	25	of	of	ADP
biomedich-632	116	26	osteitis	osteitis	NOUN
biomedich-632	116	27	moderate	moderate	ADJ
biomedich-632	116	28	degree	degree	NOUN
biomedich-632	116	29	of	of	ADP
biomedich-632	116	30	osteitis	osteitis	NOUN
biomedich-632	116	31	severe	severe	ADJ
biomedich-632	116	32	degree	degree	NOUN
biomedich-632	116	33	of	of	ADP
biomedich-632	116	34	osteitis	osteitis	NOUN
biomedich-632	116	35	osteitis	osteitis	PROPN
biomedich-632	116	36	severity	severity	NOUN
biomedich-632	116	37	and	and	CCONJ
biomedich-632	116	38	nasal	nasal	ADJ
biomedich-632	116	39	polyps	polyp	NOUN
biomedich-632	116	40	polyp	polyp	VERB
biomedich-632	116	41	non	non	ADJ
biomedich-632	116	42	-	-	ADJ
biomedich-632	116	43	polyp	polyp	ADJ
biomedich-632	116	44	handoko	handoko	NOUN
biomedich-632	116	45	et	et	PROPN
biomedich-632	116	46	al	al	PROPN
biomedich-632	116	47	.	.	PROPN
biomedich-632	116	48	–	–	PUNCT
biomedich-632	116	49	correlation	correlation	NOUN
biomedich-632	116	50	of	of	ADP
biomedich-632	116	51	bmp2	bmp2	NOUN
biomedich-632	116	52	with	with	ADP
biomedich-632	116	53	degree	degree	NOUN
biomedich-632	116	54	of	of	ADP
biomedich-632	116	55	osteitisin	osteitisin	NOUN
biomedich-632	116	56	primary	primary	ADJ
biomedich-632	116	57	crs	crs	PROPN
biomedich-632	116	58	…	…	PUNCT
biomedich-632	116	59	47	47	NUM
biomedich-632	116	60	association	association	NOUN
biomedich-632	116	61	between	between	ADP
biomedich-632	116	62	elevated	elevated	ADJ
biomedich-632	116	63	bmp2	bmp2	ADJ
biomedich-632	116	64	levels	level	NOUN
biomedich-632	116	65	and	and	CCONJ
biomedich-632	116	66	chronic	chronic	ADJ
biomedich-632	116	67	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	116	68	,	,	PUNCT
biomedich-632	116	69	whether	whether	SCONJ
biomedich-632	116	70	with	with	ADP
biomedich-632	116	71	or	or	CCONJ
biomedich-632	116	72	without	without	ADP
biomedich-632	116	73	polyps	polyp	NOUN
biomedich-632	116	74	.	.	PUNCT
biomedich-632	117	1	however	however	ADV
biomedich-632	117	2	,	,	PUNCT
biomedich-632	117	3	the	the	DET
biomedich-632	117	4	higher	high	ADJ
biomedich-632	117	5	mean	mean	ADJ
biomedich-632	117	6	bmp2	bmp2	ADJ
biomedich-632	117	7	concentration	concentration	NOUN
biomedich-632	117	8	in	in	ADP
biomedich-632	117	9	samples	sample	NOUN
biomedich-632	117	10	with	with	ADP
biomedich-632	117	11	polyps	polyp	NOUN
biomedich-632	117	12	suggests	suggest	VERB
biomedich-632	117	13	that	that	SCONJ
biomedich-632	117	14	this	this	DET
biomedich-632	117	15	significant	significant	ADJ
biomedich-632	117	16	value	value	NOUN
biomedich-632	117	17	reflects	reflect	VERB
biomedich-632	117	18	a	a	DET
biomedich-632	117	19	more	more	ADV
biomedich-632	117	20	pronounced	pronounced	ADJ
biomedich-632	117	21	increase	increase	NOUN
biomedich-632	117	22	in	in	ADP
biomedich-632	117	23	bmp2	bmp2	ADJ
biomedich-632	117	24	levels	level	NOUN
biomedich-632	117	25	in	in	ADP
biomedich-632	117	26	chronic	chronic	ADJ
biomedich-632	117	27	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	117	28	with	with	ADP
biomedich-632	117	29	polyps	polyp	NOUN
biomedich-632	117	30	compared	compare	VERB
biomedich-632	117	31	to	to	ADP
biomedich-632	117	32	those	those	PRON
biomedich-632	117	33	without	without	ADP
biomedich-632	117	34	.	.	PUNCT
biomedich-632	118	1	table	table	NOUN
biomedich-632	118	2	1	1	NUM
biomedich-632	118	3	.	.	PUNCT
biomedich-632	118	4	comparative	comparative	ADJ
biomedich-632	118	5	analysis	analysis	NOUN
biomedich-632	118	6	of	of	ADP
biomedich-632	118	7	bmp2	bmp2	ADJ
biomedich-632	118	8	levels	level	NOUN
biomedich-632	118	9	in	in	ADP
biomedich-632	118	10	crswnp	crswnp	PROPN
biomedich-632	118	11	and	and	CCONJ
biomedich-632	118	12	crssnp	crssnp	PROPN
biomedich-632	118	13	.	.	PUNCT
biomedich-632	119	1	bmp-2	bmp-2	PROPN
biomedich-632	119	2	levels	level	NOUN
biomedich-632	119	3	crswnp	crswnp	VERB
biomedich-632	119	4	/	/	SYM
biomedich-632	119	5	crssnp	crssnp	NOUN
biomedich-632	119	6	mean	mean	NOUN
biomedich-632	119	7	n	n	PRON
biomedich-632	119	8	std	std	PROPN
biomedich-632	119	9	.	.	PUNCT
biomedich-632	120	1	deviation	deviation	NOUN
biomedich-632	120	2	polyp	polyp	NOUN
biomedich-632	120	3	3.78890152	3.78890152	NUM
biomedich-632	120	4	17	17	NUM
biomedich-632	120	5	5.439027531	5.439027531	NUM
biomedich-632	120	6	non	non	ADJ
biomedich-632	120	7	polyp	polyp	NOUN
biomedich-632	120	8	1.30166566	1.30166566	NUM
biomedich-632	120	9	16	16	NUM
biomedich-632	120	10	3.658008024	3.658008024	NUM
biomedich-632	120	11	total	total	NOUN
biomedich-632	120	12	2.58296898	2.58296898	NUM
biomedich-632	120	13	33	33	NUM
biomedich-632	120	14	4.759970211	4.759970211	NUM
biomedich-632	120	15	thirty	thirty	NUM
biomedich-632	120	16	-	-	PUNCT
biomedich-632	120	17	three	three	NUM
biomedich-632	120	18	samples	sample	NOUN
biomedich-632	120	19	meeting	meet	VERB
biomedich-632	120	20	the	the	DET
biomedich-632	120	21	inclusion	inclusion	NOUN
biomedich-632	120	22	criteria	criterion	NOUN
biomedich-632	120	23	were	be	AUX
biomedich-632	120	24	assessed	assess	VERB
biomedich-632	120	25	for	for	ADP
biomedich-632	120	26	osteitis	osteitis	NOUN
biomedich-632	120	27	severity	severity	NOUN
biomedich-632	120	28	using	use	VERB
biomedich-632	120	29	the	the	DET
biomedich-632	120	30	global	global	ADJ
biomedich-632	120	31	osteitis	osteitis	NOUN
biomedich-632	120	32	scoring	scoring	NOUN
biomedich-632	120	33	scale	scale	NOUN
biomedich-632	120	34	(	(	PUNCT
biomedich-632	120	35	goss	goss	PROPN
biomedich-632	120	36	)	)	PUNCT
biomedich-632	120	37	.	.	PUNCT
biomedich-632	121	1	the	the	DET
biomedich-632	121	2	samples	sample	NOUN
biomedich-632	121	3	were	be	AUX
biomedich-632	121	4	divided	divide	VERB
biomedich-632	121	5	into	into	ADP
biomedich-632	121	6	two	two	NUM
biomedich-632	121	7	groups	group	NOUN
biomedich-632	121	8	based	base	VERB
biomedich-632	121	9	on	on	ADP
biomedich-632	121	10	the	the	DET
biomedich-632	121	11	presence	presence	NOUN
biomedich-632	121	12	of	of	ADP
biomedich-632	121	13	nasal	nasal	PROPN
biomedich-632	121	14	polyps	polyp	NOUN
biomedich-632	121	15	:	:	PUNCT
biomedich-632	121	16	17	17	NUM
biomedich-632	121	17	samples	sample	NOUN
biomedich-632	121	18	with	with	ADP
biomedich-632	121	19	chronic	chronic	ADJ
biomedich-632	121	20	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	121	21	with	with	ADP
biomedich-632	121	22	polyps	polyp	NOUN
biomedich-632	121	23	and	and	CCONJ
biomedich-632	121	24	16	16	NUM
biomedich-632	121	25	samples	sample	NOUN
biomedich-632	121	26	with	with	ADP
biomedich-632	121	27	chronic	chronic	ADJ
biomedich-632	121	28	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	121	29	without	without	ADP
biomedich-632	121	30	polyps	polyp	NOUN
biomedich-632	121	31	.	.	PUNCT
biomedich-632	122	1	the	the	DET
biomedich-632	122	2	mean	mean	PROPN
biomedich-632	122	3	goss	goss	PROPN
biomedich-632	122	4	score	score	NOUN
biomedich-632	122	5	for	for	ADP
biomedich-632	122	6	chronic	chronic	ADJ
biomedich-632	122	7	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	122	8	with	with	ADP
biomedich-632	122	9	polyps	polyp	NOUN
biomedich-632	122	10	was	be	AUX
biomedich-632	122	11	21.23	21.23	NUM
biomedich-632	122	12	,	,	PUNCT
biomedich-632	122	13	with	with	ADP
biomedich-632	122	14	a	a	DET
biomedich-632	122	15	standard	standard	ADJ
biomedich-632	122	16	deviation	deviation	NOUN
biomedich-632	122	17	9.46	9.46	NUM
biomedich-632	122	18	.	.	PUNCT
biomedich-632	123	1	in	in	ADP
biomedich-632	123	2	contrast	contrast	NOUN
biomedich-632	123	3	,	,	PUNCT
biomedich-632	123	4	the	the	DET
biomedich-632	123	5	mean	mean	PROPN
biomedich-632	123	6	goss	goss	PROPN
biomedich-632	123	7	score	score	NOUN
biomedich-632	123	8	for	for	ADP
biomedich-632	123	9	chronic	chronic	ADJ
biomedich-632	123	10	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	123	11	without	without	ADP
biomedich-632	123	12	polyps	polyp	NOUN
biomedich-632	123	13	was	be	AUX
biomedich-632	123	14	10.56	10.56	NUM
biomedich-632	123	15	,	,	PUNCT
biomedich-632	123	16	with	with	ADP
biomedich-632	123	17	a	a	DET
biomedich-632	123	18	standard	standard	ADJ
biomedich-632	123	19	deviation	deviation	NOUN
biomedich-632	123	20	7.75	7.75	NUM
biomedich-632	123	21	(	(	PUNCT
biomedich-632	123	22	table	table	NOUN
biomedich-632	123	23	2	2	NUM
biomedich-632	123	24	)	)	PUNCT
biomedich-632	123	25	.	.	PUNCT
biomedich-632	124	1	comparative	comparative	ADJ
biomedich-632	124	2	analysis	analysis	NOUN
biomedich-632	124	3	between	between	ADP
biomedich-632	124	4	chronic	chronic	ADJ
biomedich-632	124	5	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	124	6	with	with	ADP
biomedich-632	124	7	and	and	CCONJ
biomedich-632	124	8	without	without	ADP
biomedich-632	124	9	polyps	polyp	NOUN
biomedich-632	124	10	,	,	PUNCT
biomedich-632	124	11	based	base	VERB
biomedich-632	124	12	on	on	ADP
biomedich-632	124	13	goss	goss	PROPN
biomedich-632	124	14	scores	score	NOUN
biomedich-632	124	15	,	,	PUNCT
biomedich-632	124	16	revealed	reveal	VERB
biomedich-632	124	17	a	a	DET
biomedich-632	124	18	significant	significant	ADJ
biomedich-632	124	19	difference	difference	NOUN
biomedich-632	124	20	with	with	ADP
biomedich-632	124	21	a	a	DET
biomedich-632	124	22	p	p	NOUN
biomedich-632	124	23	-	-	PUNCT
biomedich-632	124	24	value	value	NOUN
biomedich-632	124	25	of	of	ADP
biomedich-632	124	26	0.002	0.002	NUM
biomedich-632	124	27	(	(	PUNCT
biomedich-632	124	28	p	p	X
biomedich-632	124	29	<	<	X
biomedich-632	124	30	0.05	0.05	NUM
biomedich-632	124	31	)	)	PUNCT
biomedich-632	124	32	.	.	PUNCT
biomedich-632	125	1	this	this	PRON
biomedich-632	125	2	indicates	indicate	VERB
biomedich-632	125	3	that	that	SCONJ
biomedich-632	125	4	the	the	DET
biomedich-632	125	5	presence	presence	NOUN
biomedich-632	125	6	of	of	ADP
biomedich-632	125	7	nasal	nasal	ADJ
biomedich-632	125	8	polyps	polyp	NOUN
biomedich-632	125	9	in	in	ADP
biomedich-632	125	10	chronic	chronic	ADJ
biomedich-632	125	11	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	125	12	is	be	AUX
biomedich-632	125	13	associated	associate	VERB
biomedich-632	125	14	with	with	ADP
biomedich-632	125	15	a	a	DET
biomedich-632	125	16	higher	high	ADJ
biomedich-632	125	17	goss	goss	PROPN
biomedich-632	125	18	score	score	NOUN
biomedich-632	125	19	compared	compare	VERB
biomedich-632	125	20	to	to	ADP
biomedich-632	125	21	cases	case	NOUN
biomedich-632	125	22	without	without	ADP
biomedich-632	125	23	polyps	polyp	NOUN
biomedich-632	125	24	.	.	PUNCT
biomedich-632	126	1	table	table	NOUN
biomedich-632	126	2	2	2	NUM
biomedich-632	126	3	.	.	PUNCT
biomedich-632	126	4	comparison	comparison	NOUN
biomedich-632	126	5	of	of	ADP
biomedich-632	126	6	goss	goss	PROPN
biomedich-632	126	7	scores	score	NOUN
biomedich-632	126	8	in	in	ADP
biomedich-632	126	9	crswnp	crswnp	PROPN
biomedich-632	126	10	and	and	CCONJ
biomedich-632	126	11	crssnp	crssnp	PROPN
biomedich-632	126	12	.	.	PUNCT
biomedich-632	127	1	goss	goss	PROPN
biomedich-632	127	2	crswnp	crswnp	PROPN
biomedich-632	127	3	/	/	SYM
biomedich-632	127	4	crssnp	crssnp	PROPN
biomedich-632	127	5	mean	mean	NOUN
biomedich-632	127	6	n	n	PRON
biomedich-632	127	7	std	std	PROPN
biomedich-632	127	8	.	.	PUNCT
biomedich-632	128	1	deviation	deviation	NOUN
biomedich-632	128	2	polyp	polyp	NOUN
biomedich-632	128	3	21.2353	21.2353	NUM
biomedich-632	128	4	17	17	NUM
biomedich-632	128	5	9.46394	9.46394	NUM
biomedich-632	128	6	non	non	ADJ
biomedich-632	128	7	polyp	polyp	NOUN
biomedich-632	128	8	10.5625	10.5625	NUM
biomedich-632	128	9	16	16	NUM
biomedich-632	128	10	7.75430	7.75430	NUM
biomedich-632	128	11	total	total	NOUN
biomedich-632	128	12	16.0606	16.0606	NUM
biomedich-632	128	13	33	33	NUM
biomedich-632	128	14	10.11478	10.11478	NUM
biomedich-632	128	15	disscussion	disscussion	NOUN
biomedich-632	128	16	a	a	DET
biomedich-632	128	17	total	total	NOUN
biomedich-632	128	18	of	of	ADP
biomedich-632	128	19	44	44	NUM
biomedich-632	128	20	patients	patient	NOUN
biomedich-632	128	21	with	with	ADP
biomedich-632	128	22	chronic	chronic	ADJ
biomedich-632	128	23	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	128	24	(	(	PUNCT
biomedich-632	128	25	crs	crs	PROPN
biomedich-632	128	26	)	)	PUNCT
biomedich-632	128	27	who	who	PRON
biomedich-632	128	28	presented	present	VERB
biomedich-632	128	29	at	at	ADP
biomedich-632	128	30	the	the	DET
biomedich-632	128	31	otolaryngology	otolaryngology	NOUN
biomedich-632	128	32	rhinology	rhinology	NOUN
biomedich-632	128	33	clinic	clinic	NOUN
biomedich-632	128	34	at	at	ADP
biomedich-632	128	35	rssa	rssa	PROPN
biomedich-632	128	36	were	be	AUX
biomedich-632	128	37	subjected	subject	VERB
biomedich-632	128	38	to	to	ADP
biomedich-632	128	39	anamnesis	anamnesis	NOUN
biomedich-632	128	40	and	and	CCONJ
biomedich-632	128	41	physical	physical	ADJ
biomedich-632	128	42	examination	examination	NOUN
biomedich-632	128	43	.	.	PUNCT
biomedich-632	129	1	among	among	ADP
biomedich-632	129	2	these	these	PRON
biomedich-632	129	3	,	,	PUNCT
biomedich-632	129	4	33	33	NUM
biomedich-632	129	5	patients	patient	NOUN
biomedich-632	129	6	met	meet	VERB
biomedich-632	129	7	the	the	DET
biomedich-632	129	8	inclusion	inclusion	NOUN
biomedich-632	129	9	and	and	CCONJ
biomedich-632	129	10	exclusion	exclusion	NOUN
biomedich-632	129	11	criteria	criterion	NOUN
biomedich-632	129	12	,	,	PUNCT
biomedich-632	129	13	and	and	CCONJ
biomedich-632	129	14	8	8	NUM
biomedich-632	129	15	patients	patient	NOUN
biomedich-632	129	16	were	be	AUX
biomedich-632	129	17	included	include	VERB
biomedich-632	129	18	as	as	ADP
biomedich-632	129	19	controls	control	NOUN
biomedich-632	129	20	.	.	PUNCT
biomedich-632	130	1	analysis	analysis	NOUN
biomedich-632	130	2	of	of	ADP
biomedich-632	130	3	the	the	DET
biomedich-632	130	4	sample	sample	NOUN
biomedich-632	130	5	's	's	PART
biomedich-632	130	6	gender	gender	NOUN
biomedich-632	130	7	distribution	distribution	NOUN
biomedich-632	130	8	revealed	reveal	VERB
biomedich-632	130	9	a	a	DET
biomedich-632	130	10	predominance	predominance	NOUN
biomedich-632	130	11	of	of	ADP
biomedich-632	130	12	females	female	NOUN
biomedich-632	130	13	,	,	PUNCT
biomedich-632	130	14	with	with	ADP
biomedich-632	130	15	21	21	NUM
biomedich-632	130	16	(	(	PUNCT
biomedich-632	130	17	63.6	63.6	NUM
biomedich-632	130	18	%	%	NOUN
biomedich-632	130	19	)	)	PUNCT
biomedich-632	130	20	female	female	ADJ
biomedich-632	130	21	patients	patient	NOUN
biomedich-632	130	22	and	and	CCONJ
biomedich-632	130	23	12	12	NUM
biomedich-632	130	24	(	(	PUNCT
biomedich-632	130	25	36.4	36.4	NUM
biomedich-632	130	26	%	%	NOUN
biomedich-632	130	27	)	)	PUNCT
biomedich-632	130	28	male	male	ADJ
biomedich-632	130	29	patients	patient	NOUN
biomedich-632	130	30	.	.	PUNCT
biomedich-632	131	1	this	this	DET
biomedich-632	131	2	finding	finding	NOUN
biomedich-632	131	3	aligns	align	VERB
biomedich-632	131	4	with	with	ADP
biomedich-632	131	5	prior	prior	ADJ
biomedich-632	131	6	research	research	NOUN
biomedich-632	131	7	,	,	PUNCT
biomedich-632	131	8	which	which	PRON
biomedich-632	131	9	also	also	ADV
biomedich-632	131	10	identified	identify	VERB
biomedich-632	131	11	a	a	DET
biomedich-632	131	12	predominance	predominance	NOUN
biomedich-632	131	13	of	of	ADP
biomedich-632	131	14	females	female	NOUN
biomedich-632	131	15	among	among	ADP
biomedich-632	131	16	crs	crs	PROPN
biomedich-632	131	17	patients	patient	NOUN
biomedich-632	131	18	,	,	PUNCT
biomedich-632	131	19	accounting	account	VERB
biomedich-632	131	20	for	for	ADP
biomedich-632	131	21	63	63	NUM
biomedich-632	131	22	%	%	NOUN
biomedich-632	131	23	of	of	ADP
biomedich-632	131	24	the	the	DET
biomedich-632	131	25	834	834	NUM
biomedich-632	131	26	samples	sample	NOUN
biomedich-632	131	27	examined	examine	VERB
biomedich-632	131	28	(	(	PUNCT
biomedich-632	131	29	de	de	X
biomedich-632	131	30	et	et	NOUN
biomedich-632	131	31	al	al	PROPN
biomedich-632	131	32	.	.	PROPN
biomedich-632	131	33	,	,	PUNCT
biomedich-632	131	34	2019	2019	NUM
biomedich-632	131	35	)	)	PUNCT
biomedich-632	131	36	.	.	PUNCT
biomedich-632	132	1	this	this	DET
biomedich-632	132	2	gender	gender	NOUN
biomedich-632	132	3	disparity	disparity	NOUN
biomedich-632	132	4	is	be	AUX
biomedich-632	132	5	corroborated	corroborate	VERB
biomedich-632	132	6	by	by	ADP
biomedich-632	132	7	data	datum	NOUN
biomedich-632	132	8	from	from	ADP
biomedich-632	132	9	the	the	DET
biomedich-632	132	10	national	national	PROPN
biomedich-632	132	11	health	health	PROPN
biomedich-632	132	12	interview	interview	NOUN
biomedich-632	132	13	survey	survey	NOUN
biomedich-632	132	14	(	(	PUNCT
biomedich-632	132	15	nhis	nhis	NOUN
biomedich-632	132	16	)	)	PUNCT
biomedich-632	132	17	in	in	ADP
biomedich-632	132	18	the	the	DET
biomedich-632	132	19	united	united	PROPN
biomedich-632	132	20	states	states	PROPN
biomedich-632	132	21	,	,	PUNCT
biomedich-632	132	22	which	which	PRON
biomedich-632	132	23	reported	report	VERB
biomedich-632	132	24	that	that	SCONJ
biomedich-632	132	25	63	63	NUM
biomedich-632	132	26	%	%	NOUN
biomedich-632	132	27	of	of	ADP
biomedich-632	132	28	crs	crs	PROPN
biomedich-632	132	29	patients	patient	NOUN
biomedich-632	132	30	were	be	AUX
biomedich-632	132	31	female	female	ADJ
biomedich-632	132	32	.	.	PUNCT
biomedich-632	133	1	similarly	similarly	ADV
biomedich-632	133	2	,	,	PUNCT
biomedich-632	133	3	a	a	DET
biomedich-632	133	4	2021	2021	NUM
biomedich-632	133	5	study	study	NOUN
biomedich-632	133	6	conducted	conduct	VERB
biomedich-632	133	7	in	in	ADP
biomedich-632	133	8	indonesia	indonesia	PROPN
biomedich-632	133	9	by	by	ADP
biomedich-632	133	10	poluan	poluan	PROPN
biomedich-632	133	11	and	and	CCONJ
biomedich-632	133	12	marlina	marlina	PROPN
biomedich-632	133	13	found	find	VERB
biomedich-632	133	14	that	that	SCONJ
biomedich-632	133	15	73.2	73.2	NUM
biomedich-632	133	16	%	%	NOUN
biomedich-632	133	17	of	of	ADP
biomedich-632	133	18	crs	crs	PROPN
biomedich-632	133	19	patients	patient	NOUN
biomedich-632	133	20	were	be	AUX
biomedich-632	133	21	female	female	ADJ
biomedich-632	133	22	,	,	PUNCT
biomedich-632	133	23	compared	compare	VERB
biomedich-632	133	24	to	to	ADP
biomedich-632	133	25	19	19	NUM
biomedich-632	133	26	%	%	NOUN
biomedich-632	133	27	male	male	ADJ
biomedich-632	133	28	patients	patient	NOUN
biomedich-632	133	29	.	.	PUNCT
biomedich-632	134	1	epidemiological	epidemiological	ADJ
biomedich-632	134	2	studies	study	NOUN
biomedich-632	134	3	further	far	ADV
biomedich-632	134	4	indicate	indicate	VERB
biomedich-632	134	5	that	that	SCONJ
biomedich-632	134	6	crs	crs	PROPN
biomedich-632	134	7	is	be	AUX
biomedich-632	134	8	nearly	nearly	ADV
biomedich-632	134	9	twice	twice	ADV
biomedich-632	134	10	as	as	ADV
biomedich-632	134	11	prevalent	prevalent	ADJ
biomedich-632	134	12	in	in	ADP
biomedich-632	134	13	females	female	NOUN
biomedich-632	134	14	as	as	ADP
biomedich-632	134	15	males	male	NOUN
biomedich-632	134	16	.	.	PUNCT
biomedich-632	135	1	the	the	DET
biomedich-632	135	2	higher	high	ADJ
biomedich-632	135	3	incidence	incidence	NOUN
biomedich-632	135	4	of	of	ADP
biomedich-632	135	5	crs	crs	PROPN
biomedich-632	135	6	in	in	ADP
biomedich-632	135	7	females	female	NOUN
biomedich-632	135	8	can	can	AUX
biomedich-632	135	9	be	be	AUX
biomedich-632	135	10	attributed	attribute	VERB
biomedich-632	135	11	to	to	ADP
biomedich-632	135	12	anatomical	anatomical	ADJ
biomedich-632	135	13	and	and	CCONJ
biomedich-632	135	14	hormonal	hormonal	ADJ
biomedich-632	135	15	differences	difference	NOUN
biomedich-632	135	16	.	.	PUNCT
biomedich-632	136	1	females	female	NOUN
biomedich-632	136	2	typically	typically	ADV
biomedich-632	136	3	have	have	VERB
biomedich-632	136	4	smaller	small	ADJ
biomedich-632	136	5	sinus	sinus	NOUN
biomedich-632	136	6	ostia	ostia	NOUN
biomedich-632	136	7	as	as	ADP
biomedich-632	136	8	males	male	NOUN
biomedich-632	136	9	,	,	PUNCT
biomedich-632	136	10	which	which	PRON
biomedich-632	136	11	may	may	AUX
biomedich-632	136	12	impair	impair	VERB
biomedich-632	136	13	sinus	sinus	NOUN
biomedich-632	136	14	drainage	drainage	NOUN
biomedich-632	136	15	and	and	CCONJ
biomedich-632	136	16	contribute	contribute	VERB
biomedich-632	136	17	to	to	ADP
biomedich-632	136	18	crs	crs	PROPN
biomedich-632	136	19	development	development	NOUN
biomedich-632	136	20	.	.	PUNCT
biomedich-632	137	1	smaller	small	ADJ
biomedich-632	137	2	ostia	ostia	NOUN
biomedich-632	137	3	increase	increase	VERB
biomedich-632	137	4	the	the	DET
biomedich-632	137	5	likelihood	likelihood	NOUN
biomedich-632	137	6	of	of	ADP
biomedich-632	137	7	obstruction	obstruction	NOUN
biomedich-632	137	8	and	and	CCONJ
biomedich-632	137	9	bacterial	bacterial	ADJ
biomedich-632	137	10	colonization	colonization	NOUN
biomedich-632	137	11	in	in	ADP
biomedich-632	137	12	the	the	DET
biomedich-632	137	13	paranasal	paranasal	ADJ
biomedich-632	137	14	sinuses	sinus	NOUN
biomedich-632	137	15	.	.	PUNCT
biomedich-632	138	1	additionally	additionally	ADV
biomedich-632	138	2	,	,	PUNCT
biomedich-632	138	3	females	female	NOUN
biomedich-632	138	4	have	have	VERB
biomedich-632	138	5	significantly	significantly	ADV
biomedich-632	138	6	higher	high	ADJ
biomedich-632	138	7	levels	level	NOUN
biomedich-632	138	8	of	of	ADP
biomedich-632	138	9	estrogen	estrogen	NOUN
biomedich-632	138	10	compared	compare	VERB
biomedich-632	138	11	to	to	ADP
biomedich-632	138	12	males	male	NOUN
biomedich-632	138	13	,	,	PUNCT
biomedich-632	138	14	which	which	PRON
biomedich-632	138	15	may	may	AUX
biomedich-632	138	16	further	far	ADV
biomedich-632	138	17	influence	influence	VERB
biomedich-632	138	18	the	the	DET
biomedich-632	138	19	prevalence	prevalence	NOUN
biomedich-632	138	20	and	and	CCONJ
biomedich-632	138	21	pathophysiology	pathophysiology	NOUN
biomedich-632	138	22	of	of	ADP
biomedich-632	138	23	crs	crs	PROPN
biomedich-632	138	24	(	(	PUNCT
biomedich-632	138	25	hulse	hulse	PROPN
biomedich-632	138	26	et	et	PROPN
biomedich-632	138	27	al	al	PROPN
biomedich-632	138	28	.	.	PROPN
biomedich-632	138	29	,	,	PUNCT
biomedich-632	138	30	2014	2014	NUM
biomedich-632	138	31	;	;	PUNCT
biomedich-632	138	32	ference	ference	NOUN
biomedich-632	138	33	et	et	NOUN
biomedich-632	138	34	al	al	PROPN
biomedich-632	138	35	.	.	PROPN
biomedich-632	138	36	,	,	PUNCT
biomedich-632	138	37	2015	2015	NUM
biomedich-632	138	38	)	)	PUNCT
biomedich-632	138	39	.	.	PUNCT
biomedich-632	139	1	the	the	DET
biomedich-632	139	2	sample	sample	NOUN
biomedich-632	139	3	population	population	NOUN
biomedich-632	139	4	's	's	PART
biomedich-632	139	5	age	age	NOUN
biomedich-632	139	6	range	range	NOUN
biomedich-632	139	7	varied	varied	ADJ
biomedich-632	139	8	from	from	ADP
biomedich-632	139	9	18	18	NUM
biomedich-632	139	10	to	to	PART
biomedich-632	139	11	68	68	NUM
biomedich-632	139	12	years	year	NOUN
biomedich-632	139	13	,	,	PUNCT
biomedich-632	139	14	with	with	ADP
biomedich-632	139	15	a	a	DET
biomedich-632	139	16	mean	mean	ADJ
biomedich-632	139	17	age	age	NOUN
biomedich-632	139	18	of	of	ADP
biomedich-632	139	19	38.36	38.36	NUM
biomedich-632	139	20	±	±	NUM
biomedich-632	139	21	15.27	15.27	NUM
biomedich-632	139	22	years	year	NOUN
biomedich-632	139	23	and	and	CCONJ
biomedich-632	139	24	a	a	DET
biomedich-632	139	25	median	median	ADJ
biomedich-632	139	26	age	age	NOUN
biomedich-632	139	27	of	of	ADP
biomedich-632	139	28	32	32	NUM
biomedich-632	139	29	years	year	NOUN
biomedich-632	139	30	.	.	PUNCT
biomedich-632	140	1	a	a	DET
biomedich-632	140	2	prior	prior	ADJ
biomedich-632	140	3	study	study	NOUN
biomedich-632	140	4	conducted	conduct	VERB
biomedich-632	140	5	in	in	ADP
biomedich-632	140	6	the	the	DET
biomedich-632	140	7	united	united	PROPN
biomedich-632	140	8	states	states	PROPN
biomedich-632	140	9	demonstrated	demonstrate	VERB
biomedich-632	140	10	an	an	DET
biomedich-632	140	11	increase	increase	NOUN
biomedich-632	140	12	in	in	ADP
biomedich-632	140	13	the	the	DET
biomedich-632	140	14	prevalence	prevalence	NOUN
biomedich-632	140	15	of	of	ADP
biomedich-632	140	16	chronic	chronic	ADJ
biomedich-632	140	17	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	140	18	(	(	PUNCT
biomedich-632	140	19	crs	crs	PROPN
biomedich-632	140	20	)	)	PUNCT
biomedich-632	140	21	with	with	ADP
biomedich-632	140	22	advancing	advance	VERB
biomedich-632	140	23	age	age	NOUN
biomedich-632	140	24	,	,	PUNCT
biomedich-632	140	25	showing	show	VERB
biomedich-632	140	26	a	a	DET
biomedich-632	140	27	2.7	2.7	NUM
biomedich-632	140	28	%	%	NOUN
biomedich-632	140	29	increase	increase	NOUN
biomedich-632	140	30	among	among	ADP
biomedich-632	140	31	individuals	individual	NOUN
biomedich-632	140	32	aged	age	VERB
biomedich-632	140	33	20–29	20–29	NUM
biomedich-632	140	34	years	year	NOUN
biomedich-632	140	35	and	and	CCONJ
biomedich-632	140	36	a	a	DET
biomedich-632	140	37	6.6	6.6	NUM
biomedich-632	140	38	%	%	NOUN
biomedich-632	140	39	increase	increase	NOUN
biomedich-632	140	40	among	among	ADP
biomedich-632	140	41	those	those	DET
biomedich-632	140	42	aged	age	VERB
biomedich-632	140	43	50–59	50–59	NUM
biomedich-632	140	44	years	year	NOUN
biomedich-632	140	45	.	.	PUNCT
biomedich-632	141	1	however	however	ADV
biomedich-632	141	2	,	,	PUNCT
biomedich-632	141	3	the	the	DET
biomedich-632	141	4	prevalence	prevalence	NOUN
biomedich-632	141	5	decreased	decrease	VERB
biomedich-632	141	6	by	by	ADP
biomedich-632	141	7	4.7	4.7	NUM
biomedich-632	141	8	%	%	NOUN
biomedich-632	141	9	after	after	ADP
biomedich-632	141	10	the	the	DET
biomedich-632	141	11	age	age	NOUN
biomedich-632	141	12	of	of	ADP
biomedich-632	141	13	60	60	NUM
biomedich-632	141	14	.	.	PUNCT
biomedich-632	142	1	data	datum	NOUN
biomedich-632	142	2	from	from	ADP
biomedich-632	142	3	dr	dr	PROPN
biomedich-632	142	4	.	.	PROPN
biomedich-632	142	5	m.	m.	PROPN
biomedich-632	142	6	djamil	djamil	PROPN
biomedich-632	142	7	general	general	PROPN
biomedich-632	142	8	hospital	hospital	PROPN
biomedich-632	142	9	in	in	ADP
biomedich-632	142	10	padang	padang	PROPN
biomedich-632	142	11	,	,	PUNCT
biomedich-632	142	12	collected	collect	VERB
biomedich-632	142	13	between	between	ADP
biomedich-632	142	14	january	january	PROPN
biomedich-632	142	15	1	1	NUM
biomedich-632	142	16	and	and	CCONJ
biomedich-632	142	17	december	december	PROPN
biomedich-632	142	18	31	31	NUM
biomedich-632	142	19	,	,	PUNCT
biomedich-632	142	20	2012	2012	NUM
biomedich-632	142	21	,	,	PUNCT
biomedich-632	142	22	indicated	indicate	VERB
biomedich-632	142	23	that	that	SCONJ
biomedich-632	142	24	crs	crs	PROPN
biomedich-632	142	25	was	be	AUX
biomedich-632	142	26	most	most	ADV
biomedich-632	142	27	prevalent	prevalent	ADJ
biomedich-632	142	28	among	among	ADP
biomedich-632	142	29	the	the	DET
biomedich-632	142	30	young	young	ADJ
biomedich-632	142	31	and	and	CCONJ
biomedich-632	142	32	adult	adult	NOUN
biomedich-632	142	33	age	age	NOUN
biomedich-632	142	34	groups	group	NOUN
biomedich-632	142	35	,	,	PUNCT
biomedich-632	142	36	accounting	account	VERB
biomedich-632	142	37	for	for	ADP
biomedich-632	142	38	61.90	61.90	NUM
biomedich-632	142	39	%	%	NOUN
biomedich-632	142	40	of	of	ADP
biomedich-632	142	41	cases	case	NOUN
biomedich-632	142	42	.	.	PUNCT
biomedich-632	143	1	similarly	similarly	ADV
biomedich-632	143	2	,	,	PUNCT
biomedich-632	143	3	research	research	NOUN
biomedich-632	143	4	by	by	ADP
biomedich-632	143	5	the	the	DET
biomedich-632	143	6	rhinology	rhinology	PROPN
biomedich-632	143	7	department	department	PROPN
biomedich-632	143	8	of	of	ADP
biomedich-632	143	9	ent	ent	PROPN
biomedich-632	143	10	-	-	PUNCT
biomedich-632	143	11	kl	kl	PROPN
biomedich-632	143	12	at	at	ADP
biomedich-632	143	13	fkui	fkui	NOUN
biomedich-632	143	14	rscm	rscm	NOUN
biomedich-632	143	15	reported	report	VERB
biomedich-632	143	16	the	the	DET
biomedich-632	143	17	highest	high	ADJ
biomedich-632	143	18	crs	crs	NOUN
biomedich-632	143	19	prevalence	prevalence	NOUN
biomedich-632	143	20	in	in	ADP
biomedich-632	143	21	adults	adult	NOUN
biomedich-632	143	22	aged	age	VERB
biomedich-632	143	23	18	18	NUM
biomedich-632	143	24	-	-	SYM
biomedich-632	143	25	75	75	NUM
biomedich-632	143	26	.	.	PUNCT
biomedich-632	144	1	the	the	DET
biomedich-632	144	2	elevated	elevated	ADJ
biomedich-632	144	3	incidence	incidence	NOUN
biomedich-632	144	4	of	of	ADP
biomedich-632	144	5	crs	crs	PROPN
biomedich-632	144	6	in	in	ADP
biomedich-632	144	7	adults	adult	NOUN
biomedich-632	144	8	is	be	AUX
biomedich-632	144	9	likely	likely	ADV
biomedich-632	144	10	related	relate	VERB
biomedich-632	144	11	to	to	ADP
biomedich-632	144	12	higher	high	ADJ
biomedich-632	144	13	levels	level	NOUN
biomedich-632	144	14	of	of	ADP
biomedich-632	144	15	social	social	ADJ
biomedich-632	144	16	activity	activity	NOUN
biomedich-632	144	17	outside	outside	ADP
biomedich-632	144	18	the	the	DET
biomedich-632	144	19	home	home	NOUN
biomedich-632	144	20	,	,	PUNCT
biomedich-632	144	21	which	which	PRON
biomedich-632	144	22	increases	increase	VERB
biomedich-632	144	23	exposure	exposure	NOUN
biomedich-632	144	24	to	to	ADP
biomedich-632	144	25	bacteria	bacteria	NOUN
biomedich-632	144	26	,	,	PUNCT
biomedich-632	144	27	viruses	virus	NOUN
biomedich-632	144	28	,	,	PUNCT
biomedich-632	144	29	and	and	CCONJ
biomedich-632	144	30	atmospheric	atmospheric	ADJ
biomedich-632	144	31	48	48	NUM
biomedich-632	144	32	biology	biology	NOUN
biomedich-632	144	33	,	,	PUNCT
biomedich-632	144	34	medicine	medicine	NOUN
biomedich-632	144	35	,	,	PUNCT
biomedich-632	144	36	&	&	CCONJ
biomedich-632	144	37	natural	natural	ADJ
biomedich-632	144	38	product	product	NOUN
biomedich-632	144	39	chemistry	chemistry	NOUN
biomedich-632	144	40	14	14	NUM
biomedich-632	144	41	(	(	PUNCT
biomedich-632	144	42	1	1	NUM
biomedich-632	144	43	)	)	PUNCT
biomedich-632	144	44	,	,	PUNCT
biomedich-632	144	45	2025	2025	NUM
biomedich-632	144	46	:	:	PUNCT
biomedich-632	144	47	43	43	NUM
biomedich-632	144	48	-	-	SYM
biomedich-632	144	49	50	50	NUM
biomedich-632	144	50	pollutants	pollutant	NOUN
biomedich-632	144	51	-	-	PUNCT
biomedich-632	144	52	environmental	environmental	ADJ
biomedich-632	144	53	factors	factor	NOUN
biomedich-632	144	54	that	that	PRON
biomedich-632	144	55	play	play	VERB
biomedich-632	144	56	a	a	DET
biomedich-632	144	57	significant	significant	ADJ
biomedich-632	144	58	role	role	NOUN
biomedich-632	144	59	in	in	ADP
biomedich-632	144	60	the	the	DET
biomedich-632	144	61	pathogenesis	pathogenesis	NOUN
biomedich-632	144	62	of	of	ADP
biomedich-632	144	63	crs	crs	PROPN
biomedich-632	144	64	(	(	PUNCT
biomedich-632	144	65	fokkens	fokken	NOUN
biomedich-632	144	66	et	et	PROPN
biomedich-632	144	67	al	al	PROPN
biomedich-632	144	68	.	.	PROPN
biomedich-632	144	69	,	,	PUNCT
biomedich-632	144	70	2012	2012	NUM
biomedich-632	144	71	)	)	PUNCT
biomedich-632	144	72	.	.	PUNCT
biomedich-632	145	1	in	in	ADP
biomedich-632	145	2	this	this	DET
biomedich-632	145	3	study	study	NOUN
biomedich-632	145	4	,	,	PUNCT
biomedich-632	145	5	a	a	DET
biomedich-632	145	6	correlation	correlation	NOUN
biomedich-632	145	7	coefficient	coefficient	NOUN
biomedich-632	145	8	of	of	ADP
biomedich-632	145	9	0.857	0.857	NUM
biomedich-632	145	10	was	be	AUX
biomedich-632	145	11	observed	observe	VERB
biomedich-632	145	12	,	,	PUNCT
biomedich-632	145	13	indicating	indicate	VERB
biomedich-632	145	14	a	a	DET
biomedich-632	145	15	very	very	ADV
biomedich-632	145	16	strong	strong	ADJ
biomedich-632	145	17	positive	positive	ADJ
biomedich-632	145	18	association	association	NOUN
biomedich-632	145	19	between	between	ADP
biomedich-632	145	20	bmp-2	bmp-2	NUM
biomedich-632	145	21	concentration	concentration	NOUN
biomedich-632	145	22	levels	level	NOUN
biomedich-632	145	23	and	and	CCONJ
biomedich-632	145	24	goss	goss	PROPN
biomedich-632	145	25	.	.	PUNCT
biomedich-632	146	1	this	this	DET
biomedich-632	146	2	positive	positive	ADJ
biomedich-632	146	3	coefficient	coefficient	NOUN
biomedich-632	146	4	suggests	suggest	VERB
biomedich-632	146	5	a	a	DET
biomedich-632	146	6	direct	direct	ADJ
biomedich-632	146	7	relationship	relationship	NOUN
biomedich-632	146	8	,	,	PUNCT
biomedich-632	146	9	where	where	SCONJ
biomedich-632	146	10	an	an	DET
biomedich-632	146	11	increase	increase	NOUN
biomedich-632	146	12	in	in	ADP
biomedich-632	146	13	bmp-2	bmp-2	DET
biomedich-632	146	14	concentration	concentration	NOUN
biomedich-632	146	15	is	be	AUX
biomedich-632	146	16	associated	associate	VERB
biomedich-632	146	17	with	with	ADP
biomedich-632	146	18	a	a	DET
biomedich-632	146	19	corresponding	corresponding	ADJ
biomedich-632	146	20	increase	increase	NOUN
biomedich-632	146	21	in	in	ADP
biomedich-632	146	22	goss	goss	PROPN
biomedich-632	146	23	levels	level	NOUN
biomedich-632	146	24	.	.	PUNCT
biomedich-632	147	1	this	this	DET
biomedich-632	147	2	finding	finding	NOUN
biomedich-632	147	3	aligns	align	VERB
biomedich-632	147	4	with	with	ADP
biomedich-632	147	5	earlier	early	ADJ
biomedich-632	147	6	research	research	NOUN
biomedich-632	147	7	by	by	ADP
biomedich-632	147	8	kim	kim	PROPN
biomedich-632	147	9	et	et	PROPN
biomedich-632	147	10	al	al	PROPN
biomedich-632	147	11	.	.	PROPN
biomedich-632	147	12	,	,	PUNCT
biomedich-632	147	13	which	which	PRON
biomedich-632	147	14	showed	show	VERB
biomedich-632	147	15	a	a	DET
biomedich-632	147	16	connection	connection	NOUN
biomedich-632	147	17	between	between	ADP
biomedich-632	147	18	bmp-2	bmp-2	NUM
biomedich-632	147	19	levels	level	NOUN
biomedich-632	147	20	and	and	CCONJ
biomedich-632	147	21	radiological	radiological	ADJ
biomedich-632	147	22	findings	finding	NOUN
biomedich-632	147	23	.	.	PUNCT
biomedich-632	148	1	in	in	ADP
biomedich-632	148	2	their	their	PRON
biomedich-632	148	3	study	study	NOUN
biomedich-632	148	4	,	,	PUNCT
biomedich-632	148	5	bmp-2	bmp-2	NUM
biomedich-632	148	6	levels	level	NOUN
biomedich-632	148	7	were	be	AUX
biomedich-632	148	8	measured	measure	VERB
biomedich-632	148	9	using	use	VERB
biomedich-632	148	10	immunohistochemical	immunohistochemical	ADJ
biomedich-632	148	11	staining	staining	NOUN
biomedich-632	148	12	,	,	PUNCT
biomedich-632	148	13	and	and	CCONJ
biomedich-632	148	14	the	the	DET
biomedich-632	148	15	results	result	NOUN
biomedich-632	148	16	demonstrated	demonstrate	VERB
biomedich-632	148	17	a	a	DET
biomedich-632	148	18	significant	significant	ADJ
biomedich-632	148	19	correlation	correlation	NOUN
biomedich-632	148	20	between	between	ADP
biomedich-632	148	21	bmp-2	bmp-2	NUM
biomedich-632	148	22	and	and	CCONJ
biomedich-632	148	23	goss	goss	PROPN
biomedich-632	148	24	values	value	NOUN
biomedich-632	148	25	(	(	PUNCT
biomedich-632	148	26	p	p	X
biomedich-632	148	27	=	=	NOUN
biomedich-632	148	28	0.003	0.003	NUM
biomedich-632	148	29	,	,	PUNCT
biomedich-632	148	30	r	r	NOUN
biomedich-632	148	31	=	=	PUNCT
biomedich-632	148	32	0.332	0.332	NUM
biomedich-632	148	33	)	)	PUNCT
biomedich-632	148	34	.	.	PUNCT
biomedich-632	149	1	because	because	SCONJ
biomedich-632	149	2	osteitis	osteitis	NOUN
biomedich-632	149	3	is	be	AUX
biomedich-632	149	4	frequently	frequently	ADV
biomedich-632	149	5	linked	link	VERB
biomedich-632	149	6	to	to	ADP
biomedich-632	149	7	the	the	DET
biomedich-632	149	8	persistence	persistence	NOUN
biomedich-632	149	9	of	of	ADP
biomedich-632	149	10	chronic	chronic	ADJ
biomedich-632	149	11	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	149	12	(	(	PUNCT
biomedich-632	149	13	crs	crs	PROPN
biomedich-632	149	14	)	)	PUNCT
biomedich-632	149	15	,	,	PUNCT
biomedich-632	149	16	the	the	DET
biomedich-632	149	17	study	study	NOUN
biomedich-632	149	18	also	also	ADV
biomedich-632	149	19	explored	explore	VERB
biomedich-632	149	20	this	this	DET
biomedich-632	149	21	aspect	aspect	NOUN
biomedich-632	149	22	and	and	CCONJ
biomedich-632	149	23	found	find	VERB
biomedich-632	149	24	that	that	SCONJ
biomedich-632	149	25	bmp-2	bmp-2	ADJ
biomedich-632	149	26	levels	level	NOUN
biomedich-632	149	27	were	be	AUX
biomedich-632	149	28	associated	associate	VERB
biomedich-632	149	29	with	with	ADP
biomedich-632	149	30	the	the	DET
biomedich-632	149	31	refractoriness	refractoriness	NOUN
biomedich-632	149	32	of	of	ADP
biomedich-632	149	33	the	the	DET
biomedich-632	149	34	disease	disease	NOUN
biomedich-632	149	35	(	(	PUNCT
biomedich-632	149	36	kim	kim	PROPN
biomedich-632	149	37	et	et	PROPN
biomedich-632	149	38	al	al	PROPN
biomedich-632	149	39	.	.	PROPN
biomedich-632	149	40	,	,	PUNCT
biomedich-632	149	41	2021	2021	NUM
biomedich-632	149	42	)	)	PUNCT
biomedich-632	149	43	.	.	PUNCT
biomedich-632	150	1	in	in	ADP
biomedich-632	150	2	this	this	DET
biomedich-632	150	3	study	study	NOUN
biomedich-632	150	4	,	,	PUNCT
biomedich-632	150	5	33	33	NUM
biomedich-632	150	6	samples	sample	NOUN
biomedich-632	150	7	that	that	PRON
biomedich-632	150	8	met	meet	VERB
biomedich-632	150	9	the	the	DET
biomedich-632	150	10	inclusion	inclusion	NOUN
biomedich-632	150	11	criteria	criterion	NOUN
biomedich-632	150	12	were	be	AUX
biomedich-632	150	13	assessed	assess	VERB
biomedich-632	150	14	for	for	ADP
biomedich-632	150	15	the	the	DET
biomedich-632	150	16	degree	degree	NOUN
biomedich-632	150	17	of	of	ADP
biomedich-632	150	18	osteitis	osteitis	NOUN
biomedich-632	150	19	using	use	VERB
biomedich-632	150	20	goss	goss	PROPN
biomedich-632	150	21	.	.	PUNCT
biomedich-632	151	1	the	the	DET
biomedich-632	151	2	samples	sample	NOUN
biomedich-632	151	3	were	be	AUX
biomedich-632	151	4	divided	divide	VERB
biomedich-632	151	5	into	into	ADP
biomedich-632	151	6	two	two	NUM
biomedich-632	151	7	groups	group	NOUN
biomedich-632	151	8	crswnp	crswnp	VERB
biomedich-632	151	9	and	and	CCONJ
biomedich-632	151	10	crssnp	crssnp	PROPN
biomedich-632	151	11	.	.	PUNCT
biomedich-632	152	1	of	of	ADP
biomedich-632	152	2	the	the	DET
biomedich-632	152	3	total	total	NOUN
biomedich-632	152	4	,	,	PUNCT
biomedich-632	152	5	17	17	NUM
biomedich-632	152	6	samples	sample	NOUN
biomedich-632	152	7	were	be	AUX
biomedich-632	152	8	classified	classify	VERB
biomedich-632	152	9	as	as	ADP
biomedich-632	152	10	crswnp	crswnp	VERB
biomedich-632	152	11	,	,	PUNCT
biomedich-632	152	12	and	and	CCONJ
biomedich-632	152	13	16	16	NUM
biomedich-632	152	14	were	be	AUX
biomedich-632	152	15	classified	classify	VERB
biomedich-632	152	16	as	as	ADP
biomedich-632	152	17	crssnp	crssnp	NOUN
biomedich-632	152	18	.	.	PUNCT
biomedich-632	153	1	a	a	DET
biomedich-632	153	2	comparative	comparative	ADJ
biomedich-632	153	3	analysis	analysis	NOUN
biomedich-632	153	4	was	be	AUX
biomedich-632	153	5	performed	perform	VERB
biomedich-632	153	6	to	to	PART
biomedich-632	153	7	evaluate	evaluate	VERB
biomedich-632	153	8	the	the	DET
biomedich-632	153	9	differences	difference	NOUN
biomedich-632	153	10	in	in	ADP
biomedich-632	153	11	goss	goss	PROPN
biomedich-632	153	12	scores	score	NOUN
biomedich-632	153	13	between	between	ADP
biomedich-632	153	14	the	the	DET
biomedich-632	153	15	two	two	NUM
biomedich-632	153	16	groups	group	NOUN
biomedich-632	153	17	,	,	PUNCT
biomedich-632	153	18	revealing	reveal	VERB
biomedich-632	153	19	a	a	DET
biomedich-632	153	20	statistically	statistically	ADV
biomedich-632	153	21	significant	significant	ADJ
biomedich-632	153	22	difference	difference	NOUN
biomedich-632	153	23	(	(	PUNCT
biomedich-632	153	24	p	p	NOUN
biomedich-632	153	25	=	=	NOUN
biomedich-632	153	26	0.002	0.002	NUM
biomedich-632	153	27	)	)	PUNCT
biomedich-632	153	28	.	.	PUNCT
biomedich-632	154	1	these	these	DET
biomedich-632	154	2	findings	finding	NOUN
biomedich-632	154	3	support	support	VERB
biomedich-632	154	4	the	the	DET
biomedich-632	154	5	hypothesis	hypothesis	NOUN
biomedich-632	154	6	that	that	PRON
biomedich-632	154	7	the	the	DET
biomedich-632	154	8	presence	presence	NOUN
biomedich-632	154	9	of	of	ADP
biomedich-632	154	10	nasal	nasal	ADJ
biomedich-632	154	11	polyps	polyp	NOUN
biomedich-632	154	12	in	in	ADP
biomedich-632	154	13	crs	crs	PROPN
biomedich-632	154	14	cases	case	NOUN
biomedich-632	154	15	is	be	AUX
biomedich-632	154	16	associated	associate	VERB
biomedich-632	154	17	with	with	ADP
biomedich-632	154	18	an	an	DET
biomedich-632	154	19	increased	increase	VERB
biomedich-632	154	20	severity	severity	NOUN
biomedich-632	154	21	of	of	ADP
biomedich-632	154	22	osteitis	osteitis	NOUN
biomedich-632	154	23	.	.	PUNCT
biomedich-632	155	1	this	this	PRON
biomedich-632	155	2	may	may	AUX
biomedich-632	155	3	be	be	AUX
biomedich-632	155	4	attributed	attribute	VERB
biomedich-632	155	5	to	to	ADP
biomedich-632	155	6	the	the	DET
biomedich-632	155	7	fact	fact	NOUN
biomedich-632	155	8	that	that	SCONJ
biomedich-632	155	9	both	both	DET
biomedich-632	155	10	osteitis	osteitis	NOUN
biomedich-632	155	11	and	and	CCONJ
biomedich-632	155	12	crswnp	crswnp	NOUN
biomedich-632	155	13	share	share	VERB
biomedich-632	155	14	a	a	DET
biomedich-632	155	15	similar	similar	ADJ
biomedich-632	155	16	inflammatory	inflammatory	ADJ
biomedich-632	155	17	profile	profile	NOUN
biomedich-632	155	18	,	,	PUNCT
biomedich-632	155	19	specifically	specifically	ADV
biomedich-632	155	20	type	type	NOUN
biomedich-632	155	21	2	2	NUM
biomedich-632	155	22	inflammation	inflammation	NOUN
biomedich-632	155	23	,	,	PUNCT
biomedich-632	155	24	characterized	characterize	VERB
biomedich-632	155	25	by	by	ADP
biomedich-632	155	26	a	a	DET
biomedich-632	155	27	predominance	predominance	NOUN
biomedich-632	155	28	of	of	ADP
biomedich-632	155	29	eosinophils	eosinophil	NOUN
biomedich-632	155	30	in	in	ADP
biomedich-632	155	31	the	the	DET
biomedich-632	155	32	chronic	chronic	ADJ
biomedich-632	155	33	inflammatory	inflammatory	ADJ
biomedich-632	155	34	process	process	NOUN
biomedich-632	155	35	.	.	PUNCT
biomedich-632	156	1	this	this	PRON
biomedich-632	156	2	suggests	suggest	VERB
biomedich-632	156	3	that	that	SCONJ
biomedich-632	156	4	when	when	SCONJ
biomedich-632	156	5	managing	manage	VERB
biomedich-632	156	6	patients	patient	NOUN
biomedich-632	156	7	with	with	ADP
biomedich-632	156	8	crs	crs	PROPN
biomedich-632	156	9	,	,	PUNCT
biomedich-632	156	10	careful	careful	ADJ
biomedich-632	156	11	attention	attention	NOUN
biomedich-632	156	12	should	should	AUX
biomedich-632	156	13	be	be	AUX
biomedich-632	156	14	paid	pay	VERB
biomedich-632	156	15	to	to	ADP
biomedich-632	156	16	the	the	DET
biomedich-632	156	17	presence	presence	NOUN
biomedich-632	156	18	of	of	ADP
biomedich-632	156	19	nasal	nasal	PROPN
biomedich-632	156	20	polyps	polyp	NOUN
biomedich-632	156	21	,	,	PUNCT
biomedich-632	156	22	as	as	SCONJ
biomedich-632	156	23	this	this	PRON
biomedich-632	156	24	can	can	AUX
biomedich-632	156	25	significantly	significantly	ADV
biomedich-632	156	26	impact	impact	VERB
biomedich-632	156	27	the	the	DET
biomedich-632	156	28	severity	severity	NOUN
biomedich-632	156	29	of	of	ADP
biomedich-632	156	30	osteitis	osteitis	NOUN
biomedich-632	156	31	and	and	CCONJ
biomedich-632	156	32	provide	provide	VERB
biomedich-632	156	33	insight	insight	NOUN
biomedich-632	156	34	into	into	ADP
biomedich-632	156	35	the	the	DET
biomedich-632	156	36	underlying	underlie	VERB
biomedich-632	156	37	inflammatory	inflammatory	ADJ
biomedich-632	156	38	burden	burden	NOUN
biomedich-632	156	39	.	.	PUNCT
biomedich-632	157	1	recognizing	recognize	VERB
biomedich-632	157	2	the	the	DET
biomedich-632	157	3	presence	presence	NOUN
biomedich-632	157	4	of	of	ADP
biomedich-632	157	5	nasal	nasal	ADJ
biomedich-632	157	6	polyps	polyp	NOUN
biomedich-632	157	7	in	in	ADP
biomedich-632	157	8	crs	crs	PROPN
biomedich-632	157	9	patients	patient	NOUN
biomedich-632	157	10	is	be	AUX
biomedich-632	157	11	crucial	crucial	ADJ
biomedich-632	157	12	in	in	ADP
biomedich-632	157	13	clinical	clinical	ADJ
biomedich-632	157	14	practice	practice	NOUN
biomedich-632	157	15	.	.	PUNCT
biomedich-632	158	1	this	this	DET
biomedich-632	158	2	awareness	awareness	NOUN
biomedich-632	158	3	not	not	PART
biomedich-632	158	4	only	only	ADV
biomedich-632	158	5	aids	aid	NOUN
biomedich-632	158	6	in	in	ADP
biomedich-632	158	7	accurately	accurately	ADV
biomedich-632	158	8	assessing	assess	VERB
biomedich-632	158	9	the	the	DET
biomedich-632	158	10	severity	severity	NOUN
biomedich-632	158	11	of	of	ADP
biomedich-632	158	12	osteitis	osteitis	NOUN
biomedich-632	158	13	using	use	VERB
biomedich-632	158	14	the	the	DET
biomedich-632	158	15	goss	goss	PROPN
biomedich-632	158	16	score	score	NOUN
biomedich-632	158	17	but	but	CCONJ
biomedich-632	158	18	also	also	ADV
biomedich-632	158	19	serves	serve	VERB
biomedich-632	158	20	as	as	ADP
biomedich-632	158	21	an	an	DET
biomedich-632	158	22	important	important	ADJ
biomedich-632	158	23	indicator	indicator	NOUN
biomedich-632	158	24	of	of	ADP
biomedich-632	158	25	the	the	DET
biomedich-632	158	26	patient	patient	NOUN
biomedich-632	158	27	's	's	PART
biomedich-632	158	28	overall	overall	ADJ
biomedich-632	158	29	inflammatory	inflammatory	ADJ
biomedich-632	158	30	status	status	NOUN
biomedich-632	158	31	.	.	PUNCT
biomedich-632	159	1	by	by	ADP
biomedich-632	159	2	considering	consider	VERB
biomedich-632	159	3	these	these	DET
biomedich-632	159	4	factors	factor	NOUN
biomedich-632	159	5	,	,	PUNCT
biomedich-632	159	6	clinicians	clinician	NOUN
biomedich-632	159	7	can	can	AUX
biomedich-632	159	8	better	well	ADV
biomedich-632	159	9	tailor	tailor	VERB
biomedich-632	159	10	their	their	PRON
biomedich-632	159	11	therapeutic	therapeutic	ADJ
biomedich-632	159	12	approaches	approach	NOUN
biomedich-632	159	13	to	to	PART
biomedich-632	159	14	address	address	VERB
biomedich-632	159	15	the	the	DET
biomedich-632	159	16	specific	specific	ADJ
biomedich-632	159	17	inflammatory	inflammatory	ADJ
biomedich-632	159	18	mechanisms	mechanism	NOUN
biomedich-632	159	19	at	at	ADP
biomedich-632	159	20	play	play	NOUN
biomedich-632	159	21	,	,	PUNCT
biomedich-632	159	22	potentially	potentially	ADV
biomedich-632	159	23	improving	improve	VERB
biomedich-632	159	24	patient	patient	ADJ
biomedich-632	159	25	outcomes	outcome	NOUN
biomedich-632	159	26	(	(	PUNCT
biomedich-632	159	27	mehta	mehta	PROPN
biomedich-632	159	28	et	et	PROPN
biomedich-632	159	29	al	al	PROPN
biomedich-632	159	30	.	.	PROPN
biomedich-632	159	31	,	,	PUNCT
biomedich-632	159	32	2008	2008	NUM
biomedich-632	159	33	)	)	PUNCT
biomedich-632	159	34	.	.	PUNCT
biomedich-632	160	1	the	the	DET
biomedich-632	160	2	relationship	relationship	NOUN
biomedich-632	160	3	between	between	ADP
biomedich-632	160	4	bmp-2	bmp-2	NUM
biomedich-632	160	5	and	and	CCONJ
biomedich-632	160	6	osteitis	osteitis	NOUN
biomedich-632	160	7	begins	begin	VERB
biomedich-632	160	8	with	with	ADP
biomedich-632	160	9	bmp-2	bmp-2	VERB
biomedich-632	160	10	binding	bind	VERB
biomedich-632	160	11	to	to	ADP
biomedich-632	160	12	its	its	PRON
biomedich-632	160	13	receptor	receptor	NOUN
biomedich-632	160	14	,	,	PUNCT
biomedich-632	160	15	bmpr-2	bmpr-2	NUM
biomedich-632	160	16	monomer	monomer	NOUN
biomedich-632	160	17	.	.	PUNCT
biomedich-632	161	1	this	this	DET
biomedich-632	161	2	binding	bind	VERB
biomedich-632	161	3	induces	induce	VERB
biomedich-632	161	4	the	the	DET
biomedich-632	161	5	dimerization	dimerization	NOUN
biomedich-632	161	6	of	of	ADP
biomedich-632	161	7	bmpr-2	bmpr-2	PROPN
biomedich-632	161	8	,	,	PUNCT
biomedich-632	161	9	which	which	PRON
biomedich-632	161	10	subsequently	subsequently	ADV
biomedich-632	161	11	recruits	recruit	VERB
biomedich-632	161	12	bmpr-1	bmpr-1	NUM
biomedich-632	161	13	to	to	PART
biomedich-632	161	14	transmit	transmit	VERB
biomedich-632	161	15	signals	signal	NOUN
biomedich-632	161	16	to	to	ADP
biomedich-632	161	17	molecules	molecule	NOUN
biomedich-632	161	18	that	that	PRON
biomedich-632	161	19	regulate	regulate	VERB
biomedich-632	161	20	intracellular	intracellular	ADJ
biomedich-632	161	21	signaling	signaling	NOUN
biomedich-632	161	22	.	.	PUNCT
biomedich-632	162	1	these	these	DET
biomedich-632	162	2	molecules	molecule	NOUN
biomedich-632	162	3	are	be	AUX
biomedich-632	162	4	smad	smad	ADJ
biomedich-632	162	5	1/5/8	1/5/8	NUM
biomedich-632	162	6	.	.	PUNCT
biomedich-632	163	1	the	the	DET
biomedich-632	163	2	bmp-2	bmp-2	NUM
biomedich-632	163	3	complex	complex	NOUN
biomedich-632	163	4	with	with	ADP
biomedich-632	163	5	bmpr-2	bmpr-2	NUM
biomedich-632	163	6	and	and	CCONJ
biomedich-632	163	7	bmpr-1	bmpr-1	NUM
biomedich-632	163	8	phosphorylates	phosphorylate	NOUN
biomedich-632	163	9	smad	smad	PROPN
biomedich-632	163	10	1/5/8	1/5/8	NUM
biomedich-632	163	11	.	.	PUNCT
biomedich-632	164	1	phosphorylated	phosphorylate	VERB
biomedich-632	164	2	smad	smad	PROPN
biomedich-632	164	3	1/5/8	1/5/8	NUM
biomedich-632	164	4	then	then	ADV
biomedich-632	164	5	binds	bind	VERB
biomedich-632	164	6	to	to	ADP
biomedich-632	164	7	smad-4	smad-4	PROPN
biomedich-632	164	8	.	.	PUNCT
biomedich-632	165	1	this	this	DET
biomedich-632	165	2	binding	bind	VERB
biomedich-632	165	3	causes	cause	VERB
biomedich-632	165	4	the	the	DET
biomedich-632	165	5	phosphorylated	phosphorylate	VERB
biomedich-632	165	6	smad	smad	NOUN
biomedich-632	165	7	1/5/8	1/5/8	NUM
biomedich-632	165	8	complex	complex	NOUN
biomedich-632	165	9	with	with	ADP
biomedich-632	165	10	smad-4	smad-4	PROPN
biomedich-632	165	11	to	to	PART
biomedich-632	165	12	enter	enter	VERB
biomedich-632	165	13	the	the	DET
biomedich-632	165	14	cell	cell	NOUN
biomedich-632	165	15	nucleus	nucleus	NOUN
biomedich-632	165	16	and	and	CCONJ
biomedich-632	165	17	activate	activate	VERB
biomedich-632	165	18	runx2	runx2	NOUN
biomedich-632	165	19	.	.	PUNCT
biomedich-632	166	1	the	the	DET
biomedich-632	166	2	activation	activation	NOUN
biomedich-632	166	3	of	of	ADP
biomedich-632	166	4	runx2	runx2	NOUN
biomedich-632	166	5	induces	induce	VERB
biomedich-632	166	6	osteocalcin	osteocalcin	PROPN
biomedich-632	166	7	(	(	PUNCT
biomedich-632	166	8	ocn	ocn	PROPN
biomedich-632	166	9	)	)	PUNCT
biomedich-632	166	10	,	,	PUNCT
biomedich-632	166	11	osteopontin	osteopontin	PROPN
biomedich-632	166	12	(	(	PUNCT
biomedich-632	166	13	opn	opn	PROPN
biomedich-632	166	14	)	)	PUNCT
biomedich-632	166	15	,	,	PUNCT
biomedich-632	166	16	alkaline	alkaline	NOUN
biomedich-632	166	17	phosphatase	phosphatase	NOUN
biomedich-632	166	18	(	(	PUNCT
biomedich-632	166	19	alp	alp	PROPN
biomedich-632	166	20	)	)	PUNCT
biomedich-632	166	21	,	,	PUNCT
biomedich-632	166	22	osteoprotegerin	osteoprotegerin	NOUN
biomedich-632	166	23	(	(	PUNCT
biomedich-632	166	24	opg	opg	PROPN
biomedich-632	166	25	)	)	PUNCT
biomedich-632	166	26	,	,	PUNCT
biomedich-632	166	27	matrix	matrix	NOUN
biomedich-632	166	28	metallopeptidase	metallopeptidase	NOUN
biomedich-632	166	29	13	13	NUM
biomedich-632	166	30	(	(	PUNCT
biomedich-632	166	31	mmp-13	mmp-13	NOUN
biomedich-632	166	32	)	)	PUNCT
biomedich-632	166	33	,	,	PUNCT
biomedich-632	166	34	and	and	CCONJ
biomedich-632	166	35	rankl	rankl	VERB
biomedich-632	166	36	,	,	PUNCT
biomedich-632	166	37	which	which	PRON
biomedich-632	166	38	are	be	AUX
biomedich-632	166	39	involved	involve	VERB
biomedich-632	166	40	in	in	ADP
biomedich-632	166	41	bone	bone	NOUN
biomedich-632	166	42	differentiation	differentiation	NOUN
biomedich-632	166	43	,	,	PUNCT
biomedich-632	166	44	formation	formation	NOUN
biomedich-632	166	45	,	,	PUNCT
biomedich-632	166	46	and	and	CCONJ
biomedich-632	166	47	turnover	turnover	NOUN
biomedich-632	166	48	.	.	PUNCT
biomedich-632	167	1	runx2	runx2	NOUN
biomedich-632	167	2	is	be	AUX
biomedich-632	167	3	also	also	ADV
biomedich-632	167	4	known	know	VERB
biomedich-632	167	5	to	to	PART
biomedich-632	167	6	induce	induce	VERB
biomedich-632	167	7	the	the	DET
biomedich-632	167	8	transcription	transcription	NOUN
biomedich-632	167	9	factor	factor	NOUN
biomedich-632	167	10	sp7	sp7	NOUN
biomedich-632	167	11	,	,	PUNCT
biomedich-632	167	12	or	or	CCONJ
biomedich-632	167	13	osterix	osterix	NOUN
biomedich-632	167	14	(	(	PUNCT
biomedich-632	167	15	sp7	sp7	NOUN
biomedich-632	167	16	/	/	SYM
biomedich-632	167	17	osx	osx	PROPN
biomedich-632	167	18	)	)	PUNCT
biomedich-632	167	19	,	,	PUNCT
biomedich-632	167	20	which	which	DET
biomedich-632	167	21	functions	function	NOUN
biomedich-632	167	22	by	by	ADP
biomedich-632	167	23	activating	activate	VERB
biomedich-632	167	24	ocn	ocn	PROPN
biomedich-632	167	25	,	,	PUNCT
biomedich-632	167	26	opn	opn	PROPN
biomedich-632	167	27	,	,	PUNCT
biomedich-632	167	28	bone	bone	NOUN
biomedich-632	167	29	sialoprotein	sialoprotein	NOUN
biomedich-632	167	30	,	,	PUNCT
biomedich-632	167	31	and	and	CCONJ
biomedich-632	167	32	type	type	NOUN
biomedich-632	167	33	1	1	NUM
biomedich-632	167	34	collagen	collagen	NOUN
biomedich-632	167	35	(	(	PUNCT
biomedich-632	167	36	col1	col1	PROPN
biomedich-632	167	37	)	)	PUNCT
biomedich-632	167	38	.	.	PUNCT
biomedich-632	168	1	these	these	DET
biomedich-632	168	2	four	four	NUM
biomedich-632	168	3	proteins	protein	NOUN
biomedich-632	168	4	play	play	VERB
biomedich-632	168	5	a	a	DET
biomedich-632	168	6	role	role	NOUN
biomedich-632	168	7	in	in	ADP
biomedich-632	168	8	bone	bone	NOUN
biomedich-632	168	9	formation	formation	NOUN
biomedich-632	168	10	.	.	PUNCT
biomedich-632	169	1	yes	yes	ADV
biomedich-632	169	2	-	-	PUNCT
biomedich-632	169	3	associated	associate	VERB
biomedich-632	169	4	protein	protein	NOUN
biomedich-632	169	5	(	(	PUNCT
biomedich-632	169	6	yap	yap	NOUN
biomedich-632	169	7	)	)	PUNCT
biomedich-632	169	8	and	and	CCONJ
biomedich-632	169	9	transcriptional	transcriptional	ADJ
biomedich-632	169	10	coactivator	coactivator	NOUN
biomedich-632	169	11	with	with	ADP
biomedich-632	169	12	pdz	pdz	NOUN
biomedich-632	169	13	-	-	PUNCT
biomedich-632	169	14	binding	bind	VERB
biomedich-632	169	15	motif	motif	NOUN
biomedich-632	169	16	(	(	PUNCT
biomedich-632	169	17	taz	taz	NOUN
biomedich-632	169	18	)	)	PUNCT
biomedich-632	169	19	are	be	AUX
biomedich-632	169	20	also	also	ADV
biomedich-632	169	21	induced	induce	VERB
biomedich-632	169	22	by	by	ADP
biomedich-632	169	23	the	the	DET
biomedich-632	169	24	phosphorylated	phosphorylate	VERB
biomedich-632	169	25	smad	smad	NOUN
biomedich-632	169	26	1/5/8	1/5/8	NUM
biomedich-632	169	27	complex	complex	NOUN
biomedich-632	169	28	with	with	ADP
biomedich-632	169	29	smad-4	smad-4	PROPN
biomedich-632	169	30	.	.	PUNCT
biomedich-632	170	1	yap	yap	PROPN
biomedich-632	170	2	/	/	SYM
biomedich-632	170	3	taz	taz	PROPN
biomedich-632	170	4	then	then	ADV
biomedich-632	170	5	enter	enter	VERB
biomedich-632	170	6	the	the	DET
biomedich-632	170	7	cell	cell	NOUN
biomedich-632	170	8	nucleus	nucleus	NOUN
biomedich-632	170	9	and	and	CCONJ
biomedich-632	170	10	bind	bind	VERB
biomedich-632	170	11	to	to	ADP
biomedich-632	170	12	transcriptional	transcriptional	ADJ
biomedich-632	170	13	enhancer	enhancer	NOUN
biomedich-632	170	14	activator	activator	NOUN
biomedich-632	170	15	domains	domain	NOUN
biomedich-632	170	16	(	(	PUNCT
biomedich-632	170	17	teads	tead	NOUN
biomedich-632	170	18	)	)	PUNCT
biomedich-632	170	19	,	,	PUNCT
biomedich-632	170	20	which	which	PRON
biomedich-632	170	21	leads	lead	VERB
biomedich-632	170	22	to	to	ADP
biomedich-632	170	23	the	the	DET
biomedich-632	170	24	activation	activation	NOUN
biomedich-632	170	25	of	of	ADP
biomedich-632	170	26	wnt	wnt	PROPN
biomedich-632	170	27	family	family	NOUN
biomedich-632	170	28	member	member	NOUN
biomedich-632	170	29	5a	5a	NUM
biomedich-632	170	30	and	and	CCONJ
biomedich-632	170	31	5b	5b	NUM
biomedich-632	170	32	(	(	PUNCT
biomedich-632	170	33	wnt5a	wnt5a	PROPN
biomedich-632	170	34	/	/	SYM
biomedich-632	170	35	b	b	NOUN
biomedich-632	170	36	)	)	PUNCT
biomedich-632	170	37	,	,	PUNCT
biomedich-632	170	38	dickkopf	dickkopf	VERB
biomedich-632	170	39	-	-	PUNCT
biomedich-632	170	40	related	relate	VERB
biomedich-632	170	41	protein	protein	NOUN
biomedich-632	170	42	1	1	NUM
biomedich-632	170	43	(	(	PUNCT
biomedich-632	170	44	dkk-1	dkk-1	NUM
biomedich-632	170	45	)	)	PUNCT
biomedich-632	170	46	,	,	PUNCT
biomedich-632	170	47	insulin	insulin	NOUN
biomedich-632	170	48	-	-	PUNCT
biomedich-632	170	49	like	like	ADJ
biomedich-632	170	50	growth	growth	NOUN
biomedich-632	170	51	factor	factor	NOUN
biomedich-632	170	52	binding	bind	VERB
biomedich-632	170	53	protein-4	protein-4	PROPN
biomedich-632	170	54	(	(	PUNCT
biomedich-632	170	55	igfbp-4	igfbp-4	NOUN
biomedich-632	170	56	)	)	PUNCT
biomedich-632	170	57	,	,	PUNCT
biomedich-632	170	58	and	and	CCONJ
biomedich-632	170	59	bmp-4	bmp-4	X
biomedich-632	170	60	.	.	PUNCT
biomedich-632	171	1	the	the	DET
biomedich-632	171	2	activation	activation	NOUN
biomedich-632	171	3	of	of	ADP
biomedich-632	171	4	these	these	DET
biomedich-632	171	5	proteins	protein	NOUN
biomedich-632	171	6	impacts	impact	VERB
biomedich-632	171	7	the	the	DET
biomedich-632	171	8	regulation	regulation	NOUN
biomedich-632	171	9	between	between	ADP
biomedich-632	171	10	osteogenesis	osteogenesis	NOUN
biomedich-632	171	11	and	and	CCONJ
biomedich-632	171	12	osteoclastogenesis	osteoclastogenesis	NOUN
biomedich-632	171	13	(	(	PUNCT
biomedich-632	171	14	cho	cho	PROPN
biomedich-632	171	15	&	&	CCONJ
biomedich-632	171	16	kwun	kwun	PROPN
biomedich-632	171	17	,	,	PUNCT
biomedich-632	171	18	2018	2018	NUM
biomedich-632	171	19	;	;	PUNCT
biomedich-632	171	20	paulini	paulini	PROPN
biomedich-632	171	21	et	et	PROPN
biomedich-632	171	22	al	al	PROPN
biomedich-632	171	23	.	.	PROPN
biomedich-632	171	24	,	,	PUNCT
biomedich-632	171	25	2021	2021	NUM
biomedich-632	171	26	)	)	PUNCT
biomedich-632	171	27	.	.	PUNCT
biomedich-632	172	1	the	the	DET
biomedich-632	172	2	relationship	relationship	NOUN
biomedich-632	172	3	between	between	ADP
biomedich-632	172	4	bmp-2	bmp-2	NUM
biomedich-632	172	5	and	and	CCONJ
biomedich-632	172	6	osteitis	osteitis	NOUN
biomedich-632	172	7	begins	begin	VERB
biomedich-632	172	8	with	with	ADP
biomedich-632	172	9	bmp-2	bmp-2	VERB
biomedich-632	172	10	binding	bind	VERB
biomedich-632	172	11	to	to	ADP
biomedich-632	172	12	its	its	PRON
biomedich-632	172	13	receptor	receptor	NOUN
biomedich-632	172	14	,	,	PUNCT
biomedich-632	172	15	the	the	DET
biomedich-632	172	16	bmpr-2	bmpr-2	NUM
biomedich-632	172	17	monomer	monomer	NOUN
biomedich-632	172	18	.	.	PUNCT
biomedich-632	173	1	this	this	DET
biomedich-632	173	2	binding	bind	VERB
biomedich-632	173	3	induces	induce	VERB
biomedich-632	173	4	the	the	DET
biomedich-632	173	5	dimerization	dimerization	NOUN
biomedich-632	173	6	of	of	ADP
biomedich-632	173	7	bmpr-2	bmpr-2	PROPN
biomedich-632	173	8	,	,	PUNCT
biomedich-632	173	9	which	which	PRON
biomedich-632	173	10	subsequently	subsequently	ADV
biomedich-632	173	11	recruits	recruit	VERB
biomedich-632	173	12	bmpr-1	bmpr-1	PROPN
biomedich-632	173	13	,	,	PUNCT
biomedich-632	173	14	a	a	DET
biomedich-632	173	15	receptor	receptor	NOUN
biomedich-632	173	16	that	that	PRON
biomedich-632	173	17	transmits	transmit	VERB
biomedich-632	173	18	signals	signal	NOUN
biomedich-632	173	19	to	to	AUX
biomedich-632	173	20	intracellular	intracellular	ADJ
biomedich-632	173	21	signaling	signal	VERB
biomedich-632	173	22	molecules	molecule	NOUN
biomedich-632	173	23	.	.	PUNCT
biomedich-632	174	1	these	these	DET
biomedich-632	174	2	molecules	molecule	NOUN
biomedich-632	174	3	include	include	VERB
biomedich-632	174	4	smad	smad	PROPN
biomedich-632	174	5	1/5/8	1/5/8	NUM
biomedich-632	174	6	.	.	PUNCT
biomedich-632	175	1	the	the	DET
biomedich-632	175	2	bmp-2	bmp-2	NUM
biomedich-632	175	3	complex	complex	NOUN
biomedich-632	175	4	with	with	ADP
biomedich-632	175	5	bmpr-2	bmpr-2	NUM
biomedich-632	175	6	and	and	CCONJ
biomedich-632	175	7	bmpr-1	bmpr-1	NUM
biomedich-632	175	8	phosphorylates	phosphorylate	NOUN
biomedich-632	175	9	smad	smad	PROPN
biomedich-632	175	10	1/5/8	1/5/8	NUM
biomedich-632	175	11	.	.	PUNCT
biomedich-632	176	1	phosphorylated	phosphorylate	VERB
biomedich-632	176	2	smad	smad	PROPN
biomedich-632	176	3	1/5/8	1/5/8	NUM
biomedich-632	176	4	then	then	ADV
biomedich-632	176	5	binds	bind	VERB
biomedich-632	176	6	to	to	ADP
biomedich-632	176	7	smad-4	smad-4	PROPN
biomedich-632	176	8	.	.	PUNCT
biomedich-632	177	1	this	this	DET
biomedich-632	177	2	binding	bind	VERB
biomedich-632	177	3	causes	cause	VERB
biomedich-632	177	4	the	the	DET
biomedich-632	177	5	phosphorylated	phosphorylate	VERB
biomedich-632	177	6	smad	smad	NOUN
biomedich-632	177	7	1/5/8	1/5/8	NUM
biomedich-632	177	8	complex	complex	NOUN
biomedich-632	177	9	with	with	ADP
biomedich-632	177	10	smad-4	smad-4	PROPN
biomedich-632	177	11	to	to	PART
biomedich-632	177	12	enter	enter	VERB
biomedich-632	177	13	the	the	DET
biomedich-632	177	14	cell	cell	NOUN
biomedich-632	177	15	nucleus	nucleus	NOUN
biomedich-632	177	16	,	,	PUNCT
biomedich-632	177	17	activating	activate	VERB
biomedich-632	177	18	runx2	runx2	NOUN
biomedich-632	177	19	.	.	PUNCT
biomedich-632	178	1	the	the	DET
biomedich-632	178	2	activation	activation	NOUN
biomedich-632	178	3	of	of	ADP
biomedich-632	178	4	runx2	runx2	NOUN
biomedich-632	178	5	induces	induce	VERB
biomedich-632	178	6	the	the	DET
biomedich-632	178	7	expression	expression	NOUN
biomedich-632	178	8	of	of	ADP
biomedich-632	178	9	osteocalcin	osteocalcin	PROPN
biomedich-632	178	10	(	(	PUNCT
biomedich-632	178	11	ocn	ocn	PROPN
biomedich-632	178	12	)	)	PUNCT
biomedich-632	178	13	,	,	PUNCT
biomedich-632	178	14	osteopontin	osteopontin	PROPN
biomedich-632	178	15	(	(	PUNCT
biomedich-632	178	16	opn	opn	PROPN
biomedich-632	178	17	)	)	PUNCT
biomedich-632	178	18	,	,	PUNCT
biomedich-632	178	19	alkaline	alkaline	NOUN
biomedich-632	178	20	phosphatase	phosphatase	NOUN
biomedich-632	178	21	(	(	PUNCT
biomedich-632	178	22	alp	alp	PROPN
biomedich-632	178	23	)	)	PUNCT
biomedich-632	178	24	,	,	PUNCT
biomedich-632	178	25	osteoprotegerin	osteoprotegerin	NOUN
biomedich-632	178	26	(	(	PUNCT
biomedich-632	178	27	opg	opg	PROPN
biomedich-632	178	28	)	)	PUNCT
biomedich-632	178	29	,	,	PUNCT
biomedich-632	178	30	matrix	matrix	NOUN
biomedich-632	178	31	metallopeptidase	metallopeptidase	NOUN
biomedich-632	178	32	13	13	NUM
biomedich-632	178	33	(	(	PUNCT
biomedich-632	178	34	mmp-13	mmp-13	NOUN
biomedich-632	178	35	)	)	PUNCT
biomedich-632	178	36	,	,	PUNCT
biomedich-632	178	37	and	and	CCONJ
biomedich-632	178	38	rankl	rankl	VERB
biomedich-632	178	39	,	,	PUNCT
biomedich-632	178	40	which	which	PRON
biomedich-632	178	41	are	be	AUX
biomedich-632	178	42	involved	involve	VERB
biomedich-632	178	43	in	in	ADP
biomedich-632	178	44	bone	bone	NOUN
biomedich-632	178	45	differentiation	differentiation	NOUN
biomedich-632	178	46	,	,	PUNCT
biomedich-632	178	47	formation	formation	NOUN
biomedich-632	178	48	,	,	PUNCT
biomedich-632	178	49	and	and	CCONJ
biomedich-632	178	50	turnover	turnover	NOUN
biomedich-632	178	51	.	.	PUNCT
biomedich-632	179	1	runx2	runx2	NOUN
biomedich-632	179	2	itself	itself	PRON
biomedich-632	179	3	can	can	AUX
biomedich-632	179	4	also	also	ADV
biomedich-632	179	5	induce	induce	VERB
biomedich-632	179	6	the	the	DET
biomedich-632	179	7	transcription	transcription	NOUN
biomedich-632	179	8	factor	factor	NOUN
biomedich-632	179	9	sp7	sp7	NOUN
biomedich-632	179	10	,	,	PUNCT
biomedich-632	179	11	also	also	ADV
biomedich-632	179	12	known	know	VERB
biomedich-632	179	13	as	as	ADP
biomedich-632	179	14	osterix	osterix	NOUN
biomedich-632	179	15	(	(	PUNCT
biomedich-632	179	16	sp7	sp7	NOUN
biomedich-632	179	17	/	/	SYM
biomedich-632	179	18	osx	osx	PROPN
biomedich-632	179	19	)	)	PUNCT
biomedich-632	179	20	,	,	PUNCT
biomedich-632	179	21	which	which	DET
biomedich-632	179	22	functions	function	NOUN
biomedich-632	179	23	by	by	ADP
biomedich-632	179	24	activating	activate	VERB
biomedich-632	179	25	ocn	ocn	PROPN
biomedich-632	179	26	,	,	PUNCT
biomedich-632	179	27	opn	opn	PROPN
biomedich-632	179	28	,	,	PUNCT
biomedich-632	179	29	bone	bone	NOUN
biomedich-632	179	30	sialoprotein	sialoprotein	NOUN
biomedich-632	179	31	,	,	PUNCT
biomedich-632	179	32	and	and	CCONJ
biomedich-632	179	33	type	type	NOUN
biomedich-632	179	34	i	i	PRON
biomedich-632	179	35	collagen	collagen	NOUN
biomedich-632	179	36	(	(	PUNCT
biomedich-632	179	37	col1	col1	PROPN
biomedich-632	179	38	)	)	PUNCT
biomedich-632	179	39	.	.	PUNCT
biomedich-632	180	1	these	these	DET
biomedich-632	180	2	four	four	NUM
biomedich-632	180	3	proteins	protein	NOUN
biomedich-632	180	4	play	play	VERB
biomedich-632	180	5	critical	critical	ADJ
biomedich-632	180	6	roles	role	NOUN
biomedich-632	180	7	in	in	ADP
biomedich-632	180	8	bone	bone	NOUN
biomedich-632	180	9	formation	formation	NOUN
biomedich-632	180	10	.	.	PUNCT
biomedich-632	181	1	yes	yes	ADV
biomedich-632	181	2	-	-	PUNCT
biomedich-632	181	3	associated	associate	VERB
biomedich-632	181	4	protein	protein	NOUN
biomedich-632	181	5	(	(	PUNCT
biomedich-632	181	6	yap	yap	NOUN
biomedich-632	181	7	)	)	PUNCT
biomedich-632	181	8	and	and	CCONJ
biomedich-632	181	9	transcriptional	transcriptional	ADJ
biomedich-632	181	10	co	co	NOUN
biomedich-632	181	11	-	-	NOUN
biomedich-632	181	12	activator	activator	NOUN
biomedich-632	181	13	with	with	ADP
biomedich-632	181	14	pdz	pdz	NOUN
biomedich-632	181	15	-	-	PUNCT
biomedich-632	181	16	binding	bind	VERB
biomedich-632	181	17	motif	motif	NOUN
biomedich-632	181	18	(	(	PUNCT
biomedich-632	181	19	taz	taz	NOUN
biomedich-632	181	20	)	)	PUNCT
biomedich-632	181	21	are	be	AUX
biomedich-632	181	22	also	also	ADV
biomedich-632	181	23	induced	induce	VERB
biomedich-632	181	24	by	by	ADP
biomedich-632	181	25	the	the	DET
biomedich-632	181	26	phosphorylated	phosphorylate	VERB
biomedich-632	181	27	smad	smad	NOUN
biomedich-632	181	28	1/5/8	1/5/8	NUM
biomedich-632	181	29	complex	complex	NOUN
biomedich-632	181	30	with	with	ADP
biomedich-632	181	31	smad-4	smad-4	PROPN
biomedich-632	181	32	.	.	PUNCT
biomedich-632	182	1	yap	yap	PROPN
biomedich-632	182	2	/	/	SYM
biomedich-632	182	3	taz	taz	PROPN
biomedich-632	182	4	then	then	ADV
biomedich-632	182	5	enter	enter	VERB
biomedich-632	182	6	the	the	DET
biomedich-632	182	7	cell	cell	NOUN
biomedich-632	182	8	nucleus	nucleus	NOUN
biomedich-632	182	9	and	and	CCONJ
biomedich-632	182	10	bind	bind	VERB
biomedich-632	182	11	to	to	ADP
biomedich-632	182	12	transcriptional	transcriptional	ADJ
biomedich-632	182	13	enhancer	enhancer	NOUN
biomedich-632	182	14	activator	activator	NOUN
biomedich-632	182	15	domains	domain	NOUN
biomedich-632	182	16	(	(	PUNCT
biomedich-632	182	17	teads	tead	NOUN
biomedich-632	182	18	)	)	PUNCT
biomedich-632	182	19	,	,	PUNCT
biomedich-632	182	20	leading	lead	VERB
biomedich-632	182	21	to	to	ADP
biomedich-632	182	22	the	the	DET
biomedich-632	182	23	activation	activation	NOUN
biomedich-632	182	24	of	of	ADP
biomedich-632	182	25	wnt	wnt	PROPN
biomedich-632	182	26	family	family	NOUN
biomedich-632	182	27	members	member	NOUN
biomedich-632	182	28	5a	5a	NUM
biomedich-632	182	29	and	and	CCONJ
biomedich-632	182	30	5b	5b	NUM
biomedich-632	182	31	(	(	PUNCT
biomedich-632	182	32	wnt5a	wnt5a	PROPN
biomedich-632	182	33	/	/	SYM
biomedich-632	182	34	b	b	NOUN
biomedich-632	182	35	)	)	PUNCT
biomedich-632	182	36	,	,	PUNCT
biomedich-632	182	37	dickkopfrelated	dickkopfrelate	VERB
biomedich-632	182	38	protein	protein	NOUN
biomedich-632	182	39	1	1	NUM
biomedich-632	182	40	(	(	PUNCT
biomedich-632	182	41	dkk-1	dkk-1	NUM
biomedich-632	182	42	)	)	PUNCT
biomedich-632	182	43	,	,	PUNCT
biomedich-632	182	44	insulin	insulin	NOUN
biomedich-632	182	45	-	-	PUNCT
biomedich-632	182	46	like	like	ADJ
biomedich-632	182	47	growth	growth	NOUN
biomedich-632	182	48	factorbinding	factorbinde	VERB
biomedich-632	182	49	protein	protein	NOUN
biomedich-632	182	50	4	4	NUM
biomedich-632	182	51	(	(	PUNCT
biomedich-632	182	52	igfbp-4	igfbp-4	NOUN
biomedich-632	182	53	)	)	PUNCT
biomedich-632	182	54	,	,	PUNCT
biomedich-632	182	55	and	and	CCONJ
biomedich-632	182	56	bmp-4	bmp-4	X
biomedich-632	182	57	.	.	PUNCT
biomedich-632	183	1	the	the	DET
biomedich-632	183	2	activation	activation	NOUN
biomedich-632	183	3	of	of	ADP
biomedich-632	183	4	these	these	DET
biomedich-632	183	5	four	four	NUM
biomedich-632	183	6	proteins	protein	NOUN
biomedich-632	183	7	has	have	VERB
biomedich-632	183	8	implications	implication	NOUN
biomedich-632	183	9	for	for	ADP
biomedich-632	183	10	the	the	DET
biomedich-632	183	11	regulation	regulation	NOUN
biomedich-632	183	12	of	of	ADP
biomedich-632	183	13	osteogenesis	osteogenesis	NOUN
biomedich-632	183	14	and	and	CCONJ
biomedich-632	183	15	osteoclastogenesis	osteoclastogenesis	NOUN
biomedich-632	183	16	(	(	PUNCT
biomedich-632	183	17	cho	cho	PROPN
biomedich-632	183	18	&	&	CCONJ
biomedich-632	183	19	kwun	kwun	PROPN
biomedich-632	183	20	,	,	PUNCT
biomedich-632	183	21	2018	2018	NUM
biomedich-632	183	22	;	;	PUNCT
biomedich-632	183	23	zhang	zhang	PROPN
biomedich-632	183	24	et	et	PROPN
biomedich-632	183	25	al	al	PROPN
biomedich-632	183	26	.	.	PROPN
biomedich-632	183	27	,	,	PUNCT
biomedich-632	183	28	2017	2017	NUM
biomedich-632	183	29	)	)	PUNCT
biomedich-632	183	30	.	.	PUNCT
biomedich-632	184	1	in	in	ADP
biomedich-632	184	2	addition	addition	NOUN
biomedich-632	184	3	to	to	ADP
biomedich-632	184	4	the	the	DET
biomedich-632	184	5	previously	previously	ADV
biomedich-632	184	6	mentioned	mention	VERB
biomedich-632	184	7	pathway	pathway	NOUN
biomedich-632	184	8	,	,	PUNCT
biomedich-632	184	9	osteitis	osteitis	NOUN
biomedich-632	184	10	in	in	ADP
biomedich-632	184	11	crs	crs	PROPN
biomedich-632	184	12	induced	induce	VERB
biomedich-632	184	13	by	by	ADP
biomedich-632	184	14	bmp-2	bmp-2	PRON
biomedich-632	184	15	can	can	AUX
biomedich-632	184	16	also	also	ADV
biomedich-632	184	17	be	be	AUX
biomedich-632	184	18	explained	explain	VERB
biomedich-632	184	19	through	through	ADP
biomedich-632	184	20	the	the	DET
biomedich-632	184	21	runx2	runx2	ADJ
biomedich-632	184	22	pathway	pathway	NOUN
biomedich-632	184	23	.	.	PUNCT
biomedich-632	185	1	runx2	runx2	NOUN
biomedich-632	185	2	is	be	AUX
biomedich-632	185	3	a	a	DET
biomedich-632	185	4	transcription	transcription	NOUN
biomedich-632	185	5	factor	factor	NOUN
biomedich-632	185	6	that	that	PRON
biomedich-632	185	7	plays	play	VERB
biomedich-632	185	8	a	a	DET
biomedich-632	185	9	crucial	crucial	ADJ
biomedich-632	185	10	role	role	NOUN
biomedich-632	185	11	in	in	ADP
biomedich-632	185	12	osteoblasts	osteoblast	NOUN
biomedich-632	185	13	’	'	PUNCT
biomedich-632	185	14	induction	induction	NOUN
biomedich-632	185	15	,	,	PUNCT
biomedich-632	185	16	proliferation	proliferation	NOUN
biomedich-632	185	17	,	,	PUNCT
biomedich-632	185	18	and	and	CCONJ
biomedich-632	185	19	maturation	maturation	NOUN
biomedich-632	185	20	.	.	PUNCT
biomedich-632	186	1	a	a	DET
biomedich-632	186	2	study	study	NOUN
biomedich-632	186	3	by	by	ADP
biomedich-632	186	4	khalmuratova	khalmuratova	PROPN
biomedich-632	186	5	et	et	PROPN
biomedich-632	186	6	al	al	PROPN
biomedich-632	186	7	.	.	PROPN
biomedich-632	186	8	demonstrated	demonstrate	VERB
biomedich-632	186	9	that	that	SCONJ
biomedich-632	186	10	the	the	DET
biomedich-632	186	11	expression	expression	NOUN
biomedich-632	186	12	of	of	ADP
biomedich-632	186	13	runx2	runx2	NOUN
biomedich-632	186	14	is	be	AUX
biomedich-632	186	15	handoko	handoko	PROPN
biomedich-632	186	16	et	et	PROPN
biomedich-632	186	17	al	al	PROPN
biomedich-632	186	18	.	.	PROPN
biomedich-632	186	19	–	–	PUNCT
biomedich-632	186	20	correlation	correlation	NOUN
biomedich-632	186	21	of	of	ADP
biomedich-632	186	22	bmp2	bmp2	NOUN
biomedich-632	186	23	with	with	ADP
biomedich-632	186	24	degree	degree	NOUN
biomedich-632	186	25	of	of	ADP
biomedich-632	186	26	osteitisin	osteitisin	NOUN
biomedich-632	186	27	primary	primary	ADJ
biomedich-632	186	28	crs	crs	PROPN
biomedich-632	186	29	…	…	PUNCT
biomedich-632	186	30	49	49	NUM
biomedich-632	186	31	elevated	elevate	VERB
biomedich-632	186	32	in	in	ADP
biomedich-632	186	33	osteoblasts	osteoblast	NOUN
biomedich-632	186	34	of	of	ADP
biomedich-632	186	35	crs	crs	NOUN
biomedich-632	186	36	patients	patient	NOUN
biomedich-632	186	37	with	with	ADP
biomedich-632	186	38	neoosteogenesis	neoosteogenesis	NOUN
biomedich-632	186	39	.	.	PUNCT
biomedich-632	187	1	moreover	moreover	ADV
biomedich-632	187	2	,	,	PUNCT
biomedich-632	187	3	runx2	runx2	NOUN
biomedich-632	187	4	can	can	AUX
biomedich-632	187	5	be	be	AUX
biomedich-632	187	6	induced	induce	VERB
biomedich-632	187	7	by	by	ADP
biomedich-632	187	8	nasal	nasal	ADJ
biomedich-632	187	9	tissue	tissue	NOUN
biomedich-632	187	10	extracts	extract	NOUN
biomedich-632	187	11	from	from	ADP
biomedich-632	187	12	crs	crs	NOUN
biomedich-632	187	13	patients	patient	NOUN
biomedich-632	187	14	exhibiting	exhibit	VERB
biomedich-632	187	15	neoosteogenesis	neoosteogenesis	NOUN
biomedich-632	187	16	.	.	PUNCT
biomedich-632	188	1	this	this	DET
biomedich-632	188	2	increased	increase	VERB
biomedich-632	188	3	expression	expression	NOUN
biomedich-632	188	4	of	of	ADP
biomedich-632	188	5	runx2	runx2	NOUN
biomedich-632	188	6	leads	lead	VERB
biomedich-632	188	7	to	to	ADP
biomedich-632	188	8	the	the	DET
biomedich-632	188	9	differentiation	differentiation	NOUN
biomedich-632	188	10	of	of	ADP
biomedich-632	188	11	osteoblasts	osteoblast	NOUN
biomedich-632	188	12	,	,	PUNCT
biomedich-632	188	13	promoting	promote	VERB
biomedich-632	188	14	neoosteogenesis	neoosteogenesis	NOUN
biomedich-632	188	15	,	,	PUNCT
biomedich-632	188	16	a	a	DET
biomedich-632	188	17	component	component	NOUN
biomedich-632	188	18	of	of	ADP
biomedich-632	188	19	osteitis	osteitis	NOUN
biomedich-632	188	20	in	in	ADP
biomedich-632	188	21	crs	crs	PROPN
biomedich-632	188	22	patients	patient	NOUN
biomedich-632	188	23	.	.	PUNCT
biomedich-632	189	1	the	the	DET
biomedich-632	189	2	expression	expression	NOUN
biomedich-632	189	3	of	of	ADP
biomedich-632	189	4	runx2	runx2	NOUN
biomedich-632	189	5	is	be	AUX
biomedich-632	189	6	also	also	ADV
biomedich-632	189	7	correlated	correlate	VERB
biomedich-632	189	8	with	with	ADP
biomedich-632	189	9	higher	high	ADJ
biomedich-632	189	10	global	global	ADJ
biomedich-632	189	11	osteitis	osteitis	NOUN
biomedich-632	189	12	scoring	scoring	NOUN
biomedich-632	189	13	scale	scale	NOUN
biomedich-632	189	14	(	(	PUNCT
biomedich-632	189	15	goss	goss	PROPN
biomedich-632	189	16	)	)	PUNCT
biomedich-632	189	17	scores	score	NOUN
biomedich-632	189	18	,	,	PUNCT
biomedich-632	189	19	which	which	PRON
biomedich-632	189	20	are	be	AUX
biomedich-632	189	21	used	use	VERB
biomedich-632	189	22	to	to	PART
biomedich-632	189	23	measure	measure	VERB
biomedich-632	189	24	the	the	DET
biomedich-632	189	25	extent	extent	NOUN
biomedich-632	189	26	of	of	ADP
biomedich-632	189	27	osteitis	osteitis	NOUN
biomedich-632	189	28	in	in	ADP
biomedich-632	189	29	crs	crs	PROPN
biomedich-632	189	30	(	(	PUNCT
biomedich-632	189	31	khalmuratova	khalmuratova	PROPN
biomedich-632	189	32	,	,	PUNCT
biomedich-632	189	33	2019	2019	NUM
biomedich-632	189	34	)	)	PUNCT
biomedich-632	189	35	.	.	PUNCT
biomedich-632	190	1	the	the	DET
biomedich-632	190	2	runx2	runx2	PROPN
biomedich-632	190	3	pathway	pathway	NOUN
biomedich-632	190	4	also	also	ADV
biomedich-632	190	5	promotes	promote	VERB
biomedich-632	190	6	the	the	DET
biomedich-632	190	7	expression	expression	NOUN
biomedich-632	190	8	of	of	ADP
biomedich-632	190	9	rankl	rankl	PROPN
biomedich-632	190	10	,	,	PUNCT
biomedich-632	190	11	a	a	DET
biomedich-632	190	12	protein	protein	NOUN
biomedich-632	190	13	involved	involve	VERB
biomedich-632	190	14	in	in	ADP
biomedich-632	190	15	bone	bone	NOUN
biomedich-632	190	16	formation	formation	NOUN
biomedich-632	190	17	,	,	PUNCT
biomedich-632	190	18	turnover	turnover	NOUN
biomedich-632	190	19	,	,	PUNCT
biomedich-632	190	20	and	and	CCONJ
biomedich-632	190	21	differentiation	differentiation	NOUN
biomedich-632	190	22	.	.	PUNCT
biomedich-632	191	1	rankl	rankl	PROPN
biomedich-632	191	2	,	,	PUNCT
biomedich-632	191	3	a	a	DET
biomedich-632	191	4	member	member	NOUN
biomedich-632	191	5	of	of	ADP
biomedich-632	191	6	the	the	DET
biomedich-632	191	7	tumor	tumor	NOUN
biomedich-632	191	8	necrosis	necrosis	NOUN
biomedich-632	191	9	factor	factor	NOUN
biomedich-632	191	10	(	(	PUNCT
biomedich-632	191	11	tnf	tnf	PROPN
biomedich-632	191	12	)	)	PUNCT
biomedich-632	191	13	family	family	NOUN
biomedich-632	191	14	,	,	PUNCT
biomedich-632	191	15	plays	play	VERB
biomedich-632	191	16	a	a	DET
biomedich-632	191	17	crucial	crucial	ADJ
biomedich-632	191	18	role	role	NOUN
biomedich-632	191	19	in	in	ADP
biomedich-632	191	20	the	the	DET
biomedich-632	191	21	differentiation	differentiation	NOUN
biomedich-632	191	22	,	,	PUNCT
biomedich-632	191	23	survival	survival	NOUN
biomedich-632	191	24	,	,	PUNCT
biomedich-632	191	25	and	and	CCONJ
biomedich-632	191	26	activity	activity	NOUN
biomedich-632	191	27	of	of	ADP
biomedich-632	191	28	osteoclasts	osteoclast	NOUN
biomedich-632	191	29	.	.	PUNCT
biomedich-632	192	1	rankl	rankl	PROPN
biomedich-632	192	2	binds	bind	VERB
biomedich-632	192	3	to	to	ADP
biomedich-632	192	4	its	its	PRON
biomedich-632	192	5	specific	specific	ADJ
biomedich-632	192	6	receptor	receptor	NOUN
biomedich-632	192	7	,	,	PUNCT
biomedich-632	192	8	rank	rank	NOUN
biomedich-632	192	9	,	,	PUNCT
biomedich-632	192	10	on	on	ADP
biomedich-632	192	11	osteoclast	osteoclast	ADJ
biomedich-632	192	12	progenitor	progenitor	NOUN
biomedich-632	192	13	cells	cell	NOUN
biomedich-632	192	14	,	,	PUNCT
biomedich-632	192	15	leading	lead	VERB
biomedich-632	192	16	to	to	ADP
biomedich-632	192	17	the	the	DET
biomedich-632	192	18	activation	activation	NOUN
biomedich-632	192	19	of	of	ADP
biomedich-632	192	20	osteoclasts	osteoclast	NOUN
biomedich-632	192	21	and	and	CCONJ
biomedich-632	192	22	subsequent	subsequent	ADJ
biomedich-632	192	23	bone	bone	NOUN
biomedich-632	192	24	resorption	resorption	NOUN
biomedich-632	192	25	.	.	PUNCT
biomedich-632	193	1	rankl	rankl	PROPN
biomedich-632	193	2	operates	operate	VERB
biomedich-632	193	3	in	in	ADP
biomedich-632	193	4	opposition	opposition	NOUN
biomedich-632	193	5	to	to	ADP
biomedich-632	193	6	osteoprotegerin	osteoprotegerin	NOUN
biomedich-632	193	7	(	(	PUNCT
biomedich-632	193	8	opg	opg	PROPN
biomedich-632	193	9	)	)	PUNCT
biomedich-632	193	10	,	,	PUNCT
biomedich-632	193	11	a	a	DET
biomedich-632	193	12	soluble	soluble	ADJ
biomedich-632	193	13	decoy	decoy	NOUN
biomedich-632	193	14	receptor	receptor	NOUN
biomedich-632	193	15	that	that	PRON
biomedich-632	193	16	binds	bind	VERB
biomedich-632	193	17	to	to	PART
biomedich-632	193	18	rank	rank	VERB
biomedich-632	193	19	.	.	PUNCT
biomedich-632	194	1	both	both	PRON
biomedich-632	194	2	rankl	rankl	VERB
biomedich-632	194	3	and	and	CCONJ
biomedich-632	194	4	opg	opg	PROPN
biomedich-632	194	5	are	be	AUX
biomedich-632	194	6	induced	induce	VERB
biomedich-632	194	7	by	by	ADP
biomedich-632	194	8	runx2	runx2	PROPN
biomedich-632	194	9	,	,	PUNCT
biomedich-632	194	10	which	which	PRON
biomedich-632	194	11	is	be	AUX
biomedich-632	194	12	activated	activate	VERB
biomedich-632	194	13	by	by	ADP
biomedich-632	194	14	bmp-2	bmp-2	PRON
biomedich-632	194	15	.	.	PUNCT
biomedich-632	195	1	mature	mature	ADJ
biomedich-632	195	2	osteoblasts	osteoblast	NOUN
biomedich-632	195	3	produce	produce	VERB
biomedich-632	195	4	opg	opg	NOUN
biomedich-632	195	5	,	,	PUNCT
biomedich-632	195	6	which	which	PRON
biomedich-632	195	7	competitively	competitively	ADV
biomedich-632	195	8	binds	bind	VERB
biomedich-632	195	9	to	to	PART
biomedich-632	195	10	rank	rank	VERB
biomedich-632	195	11	,	,	PUNCT
biomedich-632	195	12	thereby	thereby	ADV
biomedich-632	195	13	inhibiting	inhibit	VERB
biomedich-632	195	14	bone	bone	NOUN
biomedich-632	195	15	resorption	resorption	NOUN
biomedich-632	195	16	and	and	CCONJ
biomedich-632	195	17	allowing	allow	VERB
biomedich-632	195	18	bone	bone	NOUN
biomedich-632	195	19	remodeling	remodeling	NOUN
biomedich-632	195	20	to	to	PART
biomedich-632	195	21	occur	occur	VERB
biomedich-632	195	22	.	.	PUNCT
biomedich-632	196	1	rankl	rankl	VERB
biomedich-632	196	2	expression	expression	NOUN
biomedich-632	196	3	is	be	AUX
biomedich-632	196	4	elevated	elevate	VERB
biomedich-632	196	5	in	in	ADP
biomedich-632	196	6	patients	patient	NOUN
biomedich-632	196	7	with	with	ADP
biomedich-632	196	8	crs	crs	PROPN
biomedich-632	196	9	and	and	CCONJ
biomedich-632	196	10	is	be	AUX
biomedich-632	196	11	associated	associate	VERB
biomedich-632	196	12	with	with	ADP
biomedich-632	196	13	osteitis	osteitis	NOUN
biomedich-632	196	14	and	and	CCONJ
biomedich-632	196	15	disease	disease	NOUN
biomedich-632	196	16	severity	severity	NOUN
biomedich-632	196	17	(	(	PUNCT
biomedich-632	196	18	paulini	paulini	NOUN
biomedich-632	196	19	,	,	PUNCT
biomedich-632	196	20	2021	2021	NUM
biomedich-632	196	21	)	)	PUNCT
biomedich-632	196	22	.	.	PUNCT
biomedich-632	197	1	immunohistochemical	immunohistochemical	ADJ
biomedich-632	197	2	studies	study	NOUN
biomedich-632	197	3	have	have	AUX
biomedich-632	197	4	shown	show	VERB
biomedich-632	197	5	a	a	DET
biomedich-632	197	6	significantly	significantly	ADV
biomedich-632	197	7	higher	high	ADJ
biomedich-632	197	8	distribution	distribution	NOUN
biomedich-632	197	9	of	of	ADP
biomedich-632	197	10	ranklpositive	ranklpositive	ADJ
biomedich-632	197	11	cells	cell	NOUN
biomedich-632	197	12	in	in	ADP
biomedich-632	197	13	the	the	DET
biomedich-632	197	14	periosteum	periosteum	NOUN
biomedich-632	197	15	of	of	ADP
biomedich-632	197	16	crs	crs	PROPN
biomedich-632	197	17	tissues	tissue	NOUN
biomedich-632	197	18	compared	compare	VERB
biomedich-632	197	19	to	to	ADP
biomedich-632	197	20	controls	control	NOUN
biomedich-632	197	21	.	.	PUNCT
biomedich-632	198	1	additionally	additionally	ADV
biomedich-632	198	2	,	,	PUNCT
biomedich-632	198	3	rankl	rankl	VERB
biomedich-632	198	4	expression	expression	NOUN
biomedich-632	198	5	is	be	AUX
biomedich-632	198	6	higher	high	ADJ
biomedich-632	198	7	in	in	ADP
biomedich-632	198	8	patients	patient	NOUN
biomedich-632	198	9	with	with	ADP
biomedich-632	198	10	recurrent	recurrent	ADJ
biomedich-632	198	11	crs	crs	PROPN
biomedich-632	198	12	than	than	ADP
biomedich-632	198	13	in	in	ADP
biomedich-632	198	14	those	those	PRON
biomedich-632	198	15	with	with	ADP
biomedich-632	198	16	primary	primary	ADJ
biomedich-632	198	17	cases	case	NOUN
biomedich-632	198	18	.	.	PUNCT
biomedich-632	199	1	elevated	elevated	ADJ
biomedich-632	199	2	rankl	rankl	NOUN
biomedich-632	199	3	levels	level	NOUN
biomedich-632	199	4	contribute	contribute	VERB
biomedich-632	199	5	to	to	ADP
biomedich-632	199	6	the	the	DET
biomedich-632	199	7	development	development	NOUN
biomedich-632	199	8	of	of	ADP
biomedich-632	199	9	osteitis	osteitis	NOUN
biomedich-632	199	10	and	and	CCONJ
biomedich-632	199	11	may	may	AUX
biomedich-632	199	12	serve	serve	VERB
biomedich-632	199	13	as	as	ADP
biomedich-632	199	14	a	a	DET
biomedich-632	199	15	prognostic	prognostic	ADJ
biomedich-632	199	16	indicator	indicator	NOUN
biomedich-632	199	17	in	in	ADP
biomedich-632	199	18	crs	crs	PROPN
biomedich-632	199	19	.	.	PUNCT
biomedich-632	200	1	this	this	PRON
biomedich-632	200	2	suggests	suggest	VERB
biomedich-632	200	3	that	that	SCONJ
biomedich-632	200	4	the	the	DET
biomedich-632	200	5	bmp-2	bmp-2	NUM
biomedich-632	200	6	pathway	pathway	NOUN
biomedich-632	200	7	may	may	AUX
biomedich-632	200	8	play	play	VERB
biomedich-632	200	9	a	a	DET
biomedich-632	200	10	role	role	NOUN
biomedich-632	200	11	in	in	ADP
biomedich-632	200	12	inducing	induce	VERB
biomedich-632	200	13	osteitis	osteitis	NOUN
biomedich-632	200	14	in	in	ADP
biomedich-632	200	15	crs	crs	PROPN
biomedich-632	200	16	patients	patient	NOUN
biomedich-632	200	17	.	.	PUNCT
biomedich-632	201	1	however	however	ADV
biomedich-632	201	2	,	,	PUNCT
biomedich-632	201	3	the	the	DET
biomedich-632	201	4	relationship	relationship	NOUN
biomedich-632	201	5	between	between	ADP
biomedich-632	201	6	opg	opg	PROPN
biomedich-632	201	7	and	and	CCONJ
biomedich-632	201	8	osteitis	osteitis	NOUN
biomedich-632	201	9	in	in	ADP
biomedich-632	201	10	crs	crs	PROPN
biomedich-632	201	11	has	have	AUX
biomedich-632	201	12	not	not	PART
biomedich-632	201	13	yet	yet	ADV
biomedich-632	201	14	been	be	AUX
biomedich-632	201	15	well	well	ADV
biomedich-632	201	16	-	-	PUNCT
biomedich-632	201	17	defined	define	VERB
biomedich-632	201	18	(	(	PUNCT
biomedich-632	201	19	zhang	zhang	X
biomedich-632	201	20	et	et	PROPN
biomedich-632	201	21	al	al	PROPN
biomedich-632	201	22	.	.	PROPN
biomedich-632	201	23	,	,	PUNCT
biomedich-632	201	24	2017	2017	NUM
biomedich-632	201	25	;	;	PUNCT
biomedich-632	201	26	cawley	cawley	NOUN
biomedich-632	201	27	et	et	PROPN
biomedich-632	201	28	al	al	PROPN
biomedich-632	201	29	.	.	PROPN
biomedich-632	201	30	,	,	PUNCT
biomedich-632	201	31	2020	2020	NUM
biomedich-632	201	32	)	)	PUNCT
biomedich-632	201	33	.	.	PUNCT
biomedich-632	202	1	rankl	rankl	VERB
biomedich-632	202	2	expression	expression	NOUN
biomedich-632	202	3	is	be	AUX
biomedich-632	202	4	elevated	elevate	VERB
biomedich-632	202	5	in	in	ADP
biomedich-632	202	6	patients	patient	NOUN
biomedich-632	202	7	with	with	ADP
biomedich-632	202	8	chronic	chronic	ADJ
biomedich-632	202	9	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	202	10	(	(	PUNCT
biomedich-632	202	11	crs	crs	PROPN
biomedich-632	202	12	)	)	PUNCT
biomedich-632	202	13	and	and	CCONJ
biomedich-632	202	14	is	be	AUX
biomedich-632	202	15	associated	associate	VERB
biomedich-632	202	16	with	with	ADP
biomedich-632	202	17	osteitis	osteitis	NOUN
biomedich-632	202	18	and	and	CCONJ
biomedich-632	202	19	the	the	DET
biomedich-632	202	20	severity	severity	NOUN
biomedich-632	202	21	of	of	ADP
biomedich-632	202	22	the	the	DET
biomedich-632	202	23	disease	disease	NOUN
biomedich-632	202	24	.	.	PUNCT
biomedich-632	203	1	previous	previous	ADJ
biomedich-632	203	2	immunohistochemical	immunohistochemical	ADJ
biomedich-632	203	3	studies	study	NOUN
biomedich-632	203	4	have	have	AUX
biomedich-632	203	5	shown	show	VERB
biomedich-632	203	6	a	a	DET
biomedich-632	203	7	significantly	significantly	ADV
biomedich-632	203	8	higher	high	ADJ
biomedich-632	203	9	distribution	distribution	NOUN
biomedich-632	203	10	of	of	ADP
biomedich-632	203	11	rankl	rankl	NOUN
biomedich-632	203	12	-	-	PUNCT
biomedich-632	203	13	positive	positive	ADJ
biomedich-632	203	14	cells	cell	NOUN
biomedich-632	203	15	in	in	ADP
biomedich-632	203	16	the	the	DET
biomedich-632	203	17	periosteum	periosteum	NOUN
biomedich-632	203	18	of	of	ADP
biomedich-632	203	19	crs	crs	PROPN
biomedich-632	203	20	tissues	tissue	NOUN
biomedich-632	203	21	compared	compare	VERB
biomedich-632	203	22	to	to	ADP
biomedich-632	203	23	controls	control	NOUN
biomedich-632	203	24	.	.	PUNCT
biomedich-632	204	1	furthermore	furthermore	ADV
biomedich-632	204	2	,	,	PUNCT
biomedich-632	204	3	rankl	rankl	VERB
biomedich-632	204	4	expression	expression	NOUN
biomedich-632	204	5	is	be	AUX
biomedich-632	204	6	increased	increase	VERB
biomedich-632	204	7	in	in	ADP
biomedich-632	204	8	patients	patient	NOUN
biomedich-632	204	9	with	with	ADP
biomedich-632	204	10	recurrent	recurrent	ADJ
biomedich-632	204	11	crs	crs	PROPN
biomedich-632	204	12	compared	compare	VERB
biomedich-632	204	13	to	to	ADP
biomedich-632	204	14	those	those	PRON
biomedich-632	204	15	with	with	ADP
biomedich-632	204	16	primary	primary	ADJ
biomedich-632	204	17	crs	crs	PROPN
biomedich-632	204	18	.	.	PUNCT
biomedich-632	205	1	this	this	DET
biomedich-632	205	2	elevation	elevation	NOUN
biomedich-632	205	3	in	in	ADP
biomedich-632	205	4	rankl	rankl	NOUN
biomedich-632	205	5	contributes	contribute	VERB
biomedich-632	205	6	to	to	ADP
biomedich-632	205	7	the	the	DET
biomedich-632	205	8	incidence	incidence	NOUN
biomedich-632	205	9	of	of	ADP
biomedich-632	205	10	osteitis	osteitis	NOUN
biomedich-632	205	11	and	and	CCONJ
biomedich-632	205	12	could	could	AUX
biomedich-632	205	13	serve	serve	VERB
biomedich-632	205	14	as	as	ADP
biomedich-632	205	15	a	a	DET
biomedich-632	205	16	prognostic	prognostic	ADJ
biomedich-632	205	17	indicator	indicator	NOUN
biomedich-632	205	18	in	in	ADP
biomedich-632	205	19	crs	crs	PROPN
biomedich-632	205	20	.	.	PUNCT
biomedich-632	206	1	it	it	PRON
biomedich-632	206	2	is	be	AUX
biomedich-632	206	3	also	also	ADV
biomedich-632	206	4	suggested	suggest	VERB
biomedich-632	206	5	that	that	SCONJ
biomedich-632	206	6	rankl	rankl	NOUN
biomedich-632	206	7	may	may	AUX
biomedich-632	206	8	represent	represent	VERB
biomedich-632	206	9	one	one	NUM
biomedich-632	206	10	of	of	ADP
biomedich-632	206	11	the	the	DET
biomedich-632	206	12	pathways	pathway	NOUN
biomedich-632	206	13	bmp-2	bmp-2	NUM
biomedich-632	206	14	induces	induce	VERB
biomedich-632	206	15	osteitis	osteitis	NOUN
biomedich-632	206	16	in	in	ADP
biomedich-632	206	17	crs	crs	PROPN
biomedich-632	206	18	patients	patient	NOUN
biomedich-632	206	19	.	.	PUNCT
biomedich-632	207	1	however	however	ADV
biomedich-632	207	2	,	,	PUNCT
biomedich-632	207	3	there	there	PRON
biomedich-632	207	4	is	be	VERB
biomedich-632	207	5	currently	currently	ADV
biomedich-632	207	6	no	no	DET
biomedich-632	207	7	data	datum	NOUN
biomedich-632	207	8	on	on	ADP
biomedich-632	207	9	the	the	DET
biomedich-632	207	10	relationship	relationship	NOUN
biomedich-632	207	11	between	between	ADP
biomedich-632	207	12	osteoprotegerin	osteoprotegerin	NOUN
biomedich-632	207	13	(	(	PUNCT
biomedich-632	207	14	opg	opg	PROPN
biomedich-632	207	15	)	)	PUNCT
biomedich-632	207	16	and	and	CCONJ
biomedich-632	207	17	osteitis	osteitis	NOUN
biomedich-632	207	18	in	in	ADP
biomedich-632	207	19	crs	crs	PROPN
biomedich-632	207	20	(	(	PUNCT
biomedich-632	207	21	kong	kong	PROPN
biomedich-632	207	22	,	,	PUNCT
biomedich-632	207	23	2020	2020	NUM
biomedich-632	207	24	)	)	PUNCT
biomedich-632	207	25	.	.	PUNCT
biomedich-632	208	1	bmp-2	bmp-2	PUNCT
biomedich-632	208	2	is	be	AUX
biomedich-632	208	3	not	not	PART
biomedich-632	208	4	typically	typically	ADV
biomedich-632	208	5	produced	produce	VERB
biomedich-632	208	6	under	under	ADP
biomedich-632	208	7	normal	normal	ADJ
biomedich-632	208	8	conditions	condition	NOUN
biomedich-632	208	9	;	;	PUNCT
biomedich-632	208	10	its	its	PRON
biomedich-632	208	11	production	production	NOUN
biomedich-632	208	12	is	be	AUX
biomedich-632	208	13	primarily	primarily	ADV
biomedich-632	208	14	induced	induce	VERB
biomedich-632	208	15	during	during	ADP
biomedich-632	208	16	inflammation	inflammation	NOUN
biomedich-632	208	17	in	in	ADP
biomedich-632	208	18	crs	crs	PROPN
biomedich-632	208	19	.	.	PUNCT
biomedich-632	209	1	factors	factor	NOUN
biomedich-632	209	2	influencing	influence	VERB
biomedich-632	209	3	inflammation	inflammation	NOUN
biomedich-632	209	4	in	in	ADP
biomedich-632	209	5	crs	crs	PROPN
biomedich-632	209	6	include	include	VERB
biomedich-632	209	7	genetic	genetic	ADJ
biomedich-632	209	8	predisposition	predisposition	NOUN
biomedich-632	209	9	,	,	PUNCT
biomedich-632	209	10	microbial	microbial	ADJ
biomedich-632	209	11	presence	presence	NOUN
biomedich-632	209	12	,	,	PUNCT
biomedich-632	209	13	and	and	CCONJ
biomedich-632	209	14	environmental	environmental	ADJ
biomedich-632	209	15	conditions	condition	NOUN
biomedich-632	209	16	.	.	PUNCT
biomedich-632	210	1	following	follow	VERB
biomedich-632	210	2	sinonasal	sinonasal	ADJ
biomedich-632	210	3	mucosal	mucosal	NOUN
biomedich-632	210	4	inflammation	inflammation	NOUN
biomedich-632	210	5	,	,	PUNCT
biomedich-632	210	6	thymic	thymic	ADJ
biomedich-632	210	7	stromal	stromal	ADJ
biomedich-632	210	8	lymphopoietin	lymphopoietin	NOUN
biomedich-632	210	9	(	(	PUNCT
biomedich-632	210	10	tslp	tslp	ADJ
biomedich-632	210	11	)	)	PUNCT
biomedich-632	210	12	is	be	AUX
biomedich-632	210	13	induced	induce	VERB
biomedich-632	210	14	,	,	PUNCT
biomedich-632	210	15	activating	activate	VERB
biomedich-632	210	16	dendritic	dendritic	ADJ
biomedich-632	210	17	cells	cell	NOUN
biomedich-632	210	18	and	and	CCONJ
biomedich-632	210	19	subsequently	subsequently	ADV
biomedich-632	210	20	t	t	NOUN
biomedich-632	210	21	cells	cell	NOUN
biomedich-632	210	22	,	,	PUNCT
biomedich-632	210	23	leading	lead	VERB
biomedich-632	210	24	to	to	ADP
biomedich-632	210	25	a	a	DET
biomedich-632	210	26	t	t	NOUN
biomedich-632	210	27	-	-	PUNCT
biomedich-632	210	28	helper	helper	NOUN
biomedich-632	210	29	2	2	NUM
biomedich-632	210	30	(	(	PUNCT
biomedich-632	210	31	th2	th2	PROPN
biomedich-632	210	32	)	)	PUNCT
biomedich-632	210	33	immune	immune	ADJ
biomedich-632	210	34	response	response	NOUN
biomedich-632	210	35	.	.	PUNCT
biomedich-632	211	1	th2	th2	PROPN
biomedich-632	211	2	cells	cell	NOUN
biomedich-632	211	3	produce	produce	VERB
biomedich-632	211	4	interleukins	interleukin	NOUN
biomedich-632	211	5	such	such	ADJ
biomedich-632	211	6	as	as	ADP
biomedich-632	211	7	il-4	il-4	NOUN
biomedich-632	211	8	,	,	PUNCT
biomedich-632	211	9	il-13	il-13	ADV
biomedich-632	211	10	,	,	PUNCT
biomedich-632	211	11	and	and	CCONJ
biomedich-632	211	12	il-5	il-5	NOUN
biomedich-632	211	13	,	,	PUNCT
biomedich-632	211	14	resulting	result	VERB
biomedich-632	211	15	in	in	ADP
biomedich-632	211	16	the	the	DET
biomedich-632	211	17	recruitment	recruitment	NOUN
biomedich-632	211	18	of	of	ADP
biomedich-632	211	19	eosinophils	eosinophil	NOUN
biomedich-632	211	20	,	,	PUNCT
biomedich-632	211	21	neutrophils	neutrophil	NOUN
biomedich-632	211	22	,	,	PUNCT
biomedich-632	211	23	and	and	CCONJ
biomedich-632	211	24	macrophages	macrophage	NOUN
biomedich-632	211	25	.	.	PUNCT
biomedich-632	212	1	bmp-2	bmp-2	NUM
biomedich-632	212	2	production	production	NOUN
biomedich-632	212	3	is	be	AUX
biomedich-632	212	4	influenced	influence	VERB
biomedich-632	212	5	by	by	ADP
biomedich-632	212	6	inflammatory	inflammatory	ADJ
biomedich-632	212	7	cytokines	cytokine	NOUN
biomedich-632	212	8	that	that	PRON
biomedich-632	212	9	regulate	regulate	VERB
biomedich-632	212	10	smad6	smad6	NOUN
biomedich-632	212	11	signaling	signaling	NOUN
biomedich-632	212	12	,	,	PUNCT
biomedich-632	212	13	which	which	PRON
biomedich-632	212	14	in	in	ADP
biomedich-632	212	15	turn	turn	NOUN
biomedich-632	212	16	signals	signal	NOUN
biomedich-632	212	17	bmp-2	bmp-2	PRON
biomedich-632	212	18	,	,	PUNCT
biomedich-632	212	19	leading	lead	VERB
biomedich-632	212	20	to	to	ADP
biomedich-632	212	21	bone	bone	NOUN
biomedich-632	212	22	remodeling	remodeling	NOUN
biomedich-632	212	23	and	and	CCONJ
biomedich-632	212	24	osteitis.intrinsic	osteitis.intrinsic	ADJ
biomedich-632	212	25	mucosal	mucosal	NOUN
biomedich-632	212	26	inflammation	inflammation	NOUN
biomedich-632	212	27	causes	cause	VERB
biomedich-632	212	28	mucociliary	mucociliary	ADJ
biomedich-632	212	29	dysfunction	dysfunction	NOUN
biomedich-632	212	30	due	due	ADP
biomedich-632	212	31	to	to	ADP
biomedich-632	212	32	direct	direct	ADJ
biomedich-632	212	33	damage	damage	NOUN
biomedich-632	212	34	and	and	CCONJ
biomedich-632	212	35	changes	change	NOUN
biomedich-632	212	36	in	in	ADP
biomedich-632	212	37	mucus	mucus	NOUN
biomedich-632	212	38	production	production	NOUN
biomedich-632	212	39	.	.	PUNCT
biomedich-632	213	1	mucosal	mucosal	ADJ
biomedich-632	213	2	ulceration	ulceration	NOUN
biomedich-632	213	3	leads	lead	VERB
biomedich-632	213	4	to	to	ADP
biomedich-632	213	5	bacterial	bacterial	ADJ
biomedich-632	213	6	colonization	colonization	NOUN
biomedich-632	213	7	and	and	CCONJ
biomedich-632	213	8	infection	infection	NOUN
biomedich-632	213	9	,	,	PUNCT
biomedich-632	213	10	which	which	PRON
biomedich-632	213	11	further	far	ADV
biomedich-632	213	12	enhances	enhance	VERB
biomedich-632	213	13	the	the	DET
biomedich-632	213	14	inflammatory	inflammatory	ADJ
biomedich-632	213	15	response	response	NOUN
biomedich-632	213	16	and	and	CCONJ
biomedich-632	213	17	damages	damage	VERB
biomedich-632	213	18	cilia	cilia	NOUN
biomedich-632	213	19	function	function	NOUN
biomedich-632	213	20	.	.	PUNCT
biomedich-632	214	1	impaired	impaired	ADJ
biomedich-632	214	2	mucociliary	mucociliary	NOUN
biomedich-632	214	3	function	function	NOUN
biomedich-632	214	4	fails	fail	VERB
biomedich-632	214	5	to	to	PART
biomedich-632	214	6	protect	protect	VERB
biomedich-632	214	7	the	the	DET
biomedich-632	214	8	mucosa	mucosa	NOUN
biomedich-632	214	9	from	from	ADP
biomedich-632	214	10	bacterial	bacterial	ADJ
biomedich-632	214	11	colonization	colonization	NOUN
biomedich-632	214	12	,	,	PUNCT
biomedich-632	214	13	increasing	increase	VERB
biomedich-632	214	14	exposure	exposure	NOUN
biomedich-632	214	15	to	to	ADP
biomedich-632	214	16	eosinophilic	eosinophilic	ADJ
biomedich-632	214	17	mucus	mucus	NOUN
biomedich-632	214	18	(	(	PUNCT
biomedich-632	214	19	kim	kim	PROPN
biomedich-632	214	20	et	et	PROPN
biomedich-632	214	21	al	al	PROPN
biomedich-632	214	22	.	.	PROPN
biomedich-632	214	23	,	,	PUNCT
biomedich-632	214	24	2021	2021	NUM
biomedich-632	214	25	;	;	PUNCT
biomedich-632	214	26	ahern	ahern	PROPN
biomedich-632	214	27	&	&	CCONJ
biomedich-632	214	28	cervin	cervin	PROPN
biomedich-632	214	29	,	,	PUNCT
biomedich-632	214	30	2019	2019	NUM
biomedich-632	214	31	;	;	PUNCT
biomedich-632	214	32	bachert	bachert	PROPN
biomedich-632	214	33	&	&	CCONJ
biomedich-632	214	34	tomassen	tomassen	ADJ
biomedich-632	214	35	,	,	PUNCT
biomedich-632	214	36	2019	2019	NUM
biomedich-632	214	37	)	)	PUNCT
biomedich-632	214	38	.	.	PUNCT
biomedich-632	215	1	conclussion	conclussion	VERB
biomedich-632	215	2	the	the	DET
biomedich-632	215	3	degree	degree	NOUN
biomedich-632	215	4	of	of	ADP
biomedich-632	215	5	osteitis	osteitis	NOUN
biomedich-632	215	6	,	,	PUNCT
biomedich-632	215	7	as	as	SCONJ
biomedich-632	215	8	measured	measure	VERB
biomedich-632	215	9	by	by	ADP
biomedich-632	215	10	the	the	DET
biomedich-632	215	11	goss	goss	PROPN
biomedich-632	215	12	,	,	PUNCT
biomedich-632	215	13	is	be	AUX
biomedich-632	215	14	significantly	significantly	ADV
biomedich-632	215	15	higher	high	ADJ
biomedich-632	215	16	in	in	ADP
biomedich-632	215	17	chronic	chronic	ADJ
biomedich-632	215	18	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	215	19	with	with	ADP
biomedich-632	215	20	nasal	nasal	ADJ
biomedich-632	215	21	polyps	polyp	NOUN
biomedich-632	215	22	compared	compare	VERB
biomedich-632	215	23	to	to	ADP
biomedich-632	215	24	those	those	PRON
biomedich-632	215	25	without	without	ADP
biomedich-632	215	26	nasal	nasal	ADJ
biomedich-632	215	27	polyps	polyp	NOUN
biomedich-632	215	28	.	.	PUNCT
biomedich-632	216	1	the	the	DET
biomedich-632	216	2	significant	significant	ADJ
biomedich-632	216	3	increase	increase	NOUN
biomedich-632	216	4	in	in	ADP
biomedich-632	216	5	bmp-2	bmp-2	NUM
biomedich-632	216	6	levels	level	NOUN
biomedich-632	216	7	is	be	AUX
biomedich-632	216	8	strongly	strongly	ADV
biomedich-632	216	9	and	and	CCONJ
biomedich-632	216	10	positively	positively	ADV
biomedich-632	216	11	correlated	correlate	VERB
biomedich-632	216	12	with	with	ADP
biomedich-632	216	13	the	the	DET
biomedich-632	216	14	severity	severity	NOUN
biomedich-632	216	15	of	of	ADP
biomedich-632	216	16	osteitis	osteitis	NOUN
biomedich-632	216	17	,	,	PUNCT
biomedich-632	216	18	in	in	ADP
biomedich-632	216	19	patients	patient	NOUN
biomedich-632	216	20	with	with	ADP
biomedich-632	216	21	crs	crs	PROPN
biomedich-632	216	22	.	.	PUNCT
biomedich-632	217	1	acknowledgements	acknowledgement	NOUN
biomedich-632	217	2	:	:	PUNCT
biomedich-632	217	3	the	the	DET
biomedich-632	217	4	authors	author	NOUN
biomedich-632	217	5	would	would	AUX
biomedich-632	217	6	like	like	VERB
biomedich-632	217	7	to	to	PART
biomedich-632	217	8	express	express	VERB
biomedich-632	217	9	their	their	PRON
biomedich-632	217	10	sincere	sincere	ADJ
biomedich-632	217	11	gratitude	gratitude	NOUN
biomedich-632	217	12	to	to	ADP
biomedich-632	217	13	all	all	DET
biomedich-632	217	14	those	those	PRON
biomedich-632	217	15	who	who	PRON
biomedich-632	217	16	contributed	contribute	VERB
biomedich-632	217	17	to	to	ADP
biomedich-632	217	18	this	this	DET
biomedich-632	217	19	research	research	NOUN
biomedich-632	217	20	.	.	PUNCT
biomedich-632	218	1	authors	author	NOUN
biomedich-632	218	2	’	'	PUNCT
biomedich-632	218	3	contribution	contribution	NOUN
biomedich-632	218	4	:	:	PUNCT
biomedich-632	218	5	edi	edi	PROPN
biomedich-632	218	6	handoko	handoko	PROPN
biomedich-632	218	7	&	&	CCONJ
biomedich-632	218	8	david	david	PROPN
biomedich-632	218	9	santoso	santoso	PROPN
biomedich-632	218	10	conducted	conduct	VERB
biomedich-632	218	11	the	the	DET
biomedich-632	218	12	research	research	NOUN
biomedich-632	218	13	and	and	CCONJ
biomedich-632	218	14	collected	collect	VERB
biomedich-632	218	15	data	datum	NOUN
biomedich-632	218	16	.	.	PUNCT
biomedich-632	219	1	iriana	iriana	PROPN
biomedich-632	219	2	maharani	maharani	PROPN
biomedich-632	219	3	provided	provide	VERB
biomedich-632	219	4	oversight	oversight	NOUN
biomedich-632	219	5	of	of	ADP
biomedich-632	219	6	the	the	DET
biomedich-632	219	7	study	study	NOUN
biomedich-632	219	8	design	design	NOUN
biomedich-632	219	9	and	and	CCONJ
biomedich-632	219	10	implementation	implementation	NOUN
biomedich-632	219	11	.	.	PUNCT
biomedich-632	220	1	yuyun	yuyun	PROPN
biomedich-632	220	2	yueniwati	yueniwati	PROPN
biomedich-632	220	3	p.w	p.w	PROPN
biomedich-632	220	4	.	.	PROPN
biomedich-632	220	5	offered	offer	VERB
biomedich-632	220	6	additional	additional	ADJ
biomedich-632	220	7	guidance	guidance	NOUN
biomedich-632	220	8	and	and	CCONJ
biomedich-632	220	9	support	support	NOUN
biomedich-632	220	10	throughout	throughout	ADP
biomedich-632	220	11	the	the	DET
biomedich-632	220	12	research	research	NOUN
biomedich-632	220	13	process	process	NOUN
biomedich-632	220	14	.	.	PUNCT
biomedich-632	221	1	tanti	tanti	PROPN
biomedich-632	221	2	agustina	agustina	PROPN
biomedich-632	221	3	assisted	assist	VERB
biomedich-632	221	4	to	to	ADP
biomedich-632	221	5	drafting	draft	VERB
biomedich-632	221	6	and	and	CCONJ
biomedich-632	221	7	revising	revise	VERB
biomedich-632	221	8	the	the	DET
biomedich-632	221	9	manuscript	manuscript	NOUN
biomedich-632	221	10	.	.	PUNCT
biomedich-632	222	1	competing	compete	VERB
biomedich-632	222	2	interests	interest	NOUN
biomedich-632	222	3	:	:	PUNCT
biomedich-632	222	4	the	the	DET
biomedich-632	222	5	authors	author	NOUN
biomedich-632	222	6	declare	declare	VERB
biomedich-632	222	7	that	that	SCONJ
biomedich-632	222	8	there	there	PRON
biomedich-632	222	9	are	be	VERB
biomedich-632	222	10	no	no	DET
biomedich-632	222	11	competing	compete	VERB
biomedich-632	222	12	interests	interest	NOUN
biomedich-632	222	13	.	.	PUNCT
biomedich-632	223	1	references	reference	NOUN
biomedich-632	223	2	ahern	ahern	PROPN
biomedich-632	223	3	,	,	PUNCT
biomedich-632	223	4	s.	s.	PROPN
biomedich-632	223	5	,	,	PUNCT
biomedich-632	223	6	&	&	CCONJ
biomedich-632	223	7	cervin	cervin	PROPN
biomedich-632	223	8	,	,	PUNCT
biomedich-632	223	9	a.	a.	NOUN
biomedich-632	223	10	(	(	PUNCT
biomedich-632	223	11	2019	2019	NUM
biomedich-632	223	12	)	)	PUNCT
biomedich-632	223	13	.	.	PUNCT
biomedich-632	224	1	inflammation	inflammation	NOUN
biomedich-632	224	2	and	and	CCONJ
biomedich-632	224	3	endotyping	endotype	VERB
biomedich-632	224	4	in	in	ADP
biomedich-632	224	5	chronic	chronic	ADJ
biomedich-632	224	6	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	224	7	-	-	PUNCT
biomedich-632	224	8	a	a	DET
biomedich-632	224	9	paradigm	paradigm	NOUN
biomedich-632	224	10	shift	shift	NOUN
biomedich-632	224	11	.	.	PUNCT
biomedich-632	225	1	medicina	medicina	NOUN
biomedich-632	225	2	,	,	PUNCT
biomedich-632	225	3	55(4	55(4	PROPN
biomedich-632	225	4	)	)	PUNCT
biomedich-632	225	5	,	,	PUNCT
biomedich-632	225	6	95	95	NUM
biomedich-632	225	7	.	.	PUNCT
biomedich-632	226	1	amanda	amanda	PROPN
biomedich-632	226	2	s.	s.	PROPN
biomedich-632	226	3	battisti	battisti	PROPN
biomedich-632	226	4	,	,	PUNCT
biomedich-632	226	5	pranav	pranav	PROPN
biomedich-632	226	6	modi	modi	PROPN
biomedich-632	226	7	&	&	CCONJ
biomedich-632	226	8	jon	jon	PROPN
biomedich-632	226	9	pangia	pangia	PROPN
biomedich-632	226	10	.	.	PUNCT
biomedich-632	227	1	(	(	PUNCT
biomedich-632	227	2	2020	2020	NUM
biomedich-632	227	3	)	)	PUNCT
biomedich-632	227	4	.	.	PUNCT
biomedich-632	228	1	sinusitis	sinusitis	NOUN
biomedich-632	228	2	.	.	PUNCT
biomedich-632	229	1	statpearls	statpearls	PROPN
biomedich-632	229	2	.	.	PUNCT
biomedich-632	230	1	florida	florida	PROPN
biomedich-632	230	2	.	.	PUNCT
biomedich-632	231	1	bachert	bachert	PROPN
biomedich-632	231	2	,	,	PUNCT
biomedich-632	231	3	c.	c.	PROPN
biomedich-632	231	4	,	,	PUNCT
biomedich-632	231	5	&	&	CCONJ
biomedich-632	231	6	tomassen	tomassen	ADJ
biomedich-632	231	7	,	,	PUNCT
biomedich-632	231	8	p.	p.	NOUN
biomedich-632	231	9	(	(	PUNCT
biomedich-632	231	10	2019	2019	NUM
biomedich-632	231	11	)	)	PUNCT
biomedich-632	231	12	.	.	PUNCT
biomedich-632	232	1	endotype	endotype	NOUN
biomedich-632	232	2	-	-	PUNCT
biomedich-632	232	3	driven	drive	VERB
biomedich-632	232	4	approach	approach	NOUN
biomedich-632	232	5	for	for	ADP
biomedich-632	232	6	chronic	chronic	ADJ
biomedich-632	232	7	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	232	8	.	.	PUNCT
biomedich-632	233	1	in	in	ADP
biomedich-632	233	2	implementing	implement	VERB
biomedich-632	233	3	precision	precision	NOUN
biomedich-632	233	4	medicine	medicine	NOUN
biomedich-632	233	5	in	in	ADP
biomedich-632	233	6	best	good	ADJ
biomedich-632	233	7	practices	practice	NOUN
biomedich-632	233	8	of	of	ADP
biomedich-632	233	9	chronic	chronic	ADJ
biomedich-632	233	10	airway	airway	NOUN
biomedich-632	233	11	diseases	disease	NOUN
biomedich-632	233	12	(	(	PUNCT
biomedich-632	233	13	pp	pp	ADJ
biomedich-632	233	14	.	.	PUNCT
biomedich-632	234	1	51	51	NUM
biomedich-632	234	2	-	-	SYM
biomedich-632	234	3	57	57	NUM
biomedich-632	234	4	)	)	PUNCT
biomedich-632	234	5	.	.	PUNCT
biomedich-632	235	1	academic	academic	ADJ
biomedich-632	235	2	press	press	NOUN
biomedich-632	235	3	.	.	PUNCT
biomedich-632	236	1	cambrige	cambrige	NOUN
biomedich-632	236	2	.	.	PUNCT
biomedich-632	237	1	50	50	NUM
biomedich-632	237	2	biology	biology	NOUN
biomedich-632	237	3	,	,	PUNCT
biomedich-632	237	4	medicine	medicine	NOUN
biomedich-632	237	5	,	,	PUNCT
biomedich-632	237	6	&	&	CCONJ
biomedich-632	237	7	natural	natural	ADJ
biomedich-632	237	8	product	product	NOUN
biomedich-632	237	9	chemistry	chemistry	NOUN
biomedich-632	237	10	14	14	NUM
biomedich-632	237	11	(	(	PUNCT
biomedich-632	237	12	1	1	NUM
biomedich-632	237	13	)	)	PUNCT
biomedich-632	237	14	,	,	PUNCT
biomedich-632	237	15	2025	2025	NUM
biomedich-632	237	16	:	:	PUNCT
biomedich-632	237	17	43	43	NUM
biomedich-632	237	18	-	-	SYM
biomedich-632	237	19	50	50	NUM
biomedich-632	237	20	brandi	brandi	PROPN
biomedich-632	237	21	henson	henson	PROPN
biomedich-632	237	22	,	,	PUNCT
biomedich-632	237	23	taylor	taylor	PROPN
biomedich-632	237	24	m.	m.	PROPN
biomedich-632	237	25	drake	drake	PROPN
biomedich-632	237	26	&	&	CCONJ
biomedich-632	237	27	mary	mary	PROPN
biomedich-632	237	28	ann	ann	PROPN
biomedich-632	237	29	edens	edens	PROPN
biomedich-632	237	30	.	.	PUNCT
biomedich-632	238	1	(	(	PUNCT
biomedich-632	238	2	2019	2019	NUM
biomedich-632	238	3	)	)	PUNCT
biomedich-632	238	4	.	.	PUNCT
biomedich-632	239	1	anatomy	anatomy	NOUN
biomedich-632	239	2	,	,	PUNCT
biomedich-632	239	3	head	head	NOUN
biomedich-632	239	4	and	and	CCONJ
biomedich-632	239	5	neck	neck	NOUN
biomedich-632	239	6	,	,	PUNCT
biomedich-632	239	7	nose	nose	NOUN
biomedich-632	239	8	sinuses	sinus	NOUN
biomedich-632	239	9	.	.	PUNCT
biomedich-632	240	1	statpearls	statpearls	PROPN
biomedich-632	240	2	.	.	PUNCT
biomedich-632	241	1	florida	florida	PROPN
biomedich-632	241	2	.	.	PUNCT
biomedich-632	242	1	cawley	cawley	PROPN
biomedich-632	242	2	,	,	PUNCT
biomedich-632	242	3	k.	k.	PROPN
biomedich-632	242	4	m.	m.	PROPN
biomedich-632	242	5	,	,	PUNCT
biomedich-632	242	6	bustamante	bustamante	PROPN
biomedich-632	242	7	-	-	PUNCT
biomedich-632	242	8	gomez	gomez	PROPN
biomedich-632	242	9	,	,	PUNCT
biomedich-632	242	10	n.	n.	PROPN
biomedich-632	242	11	c.	c.	PROPN
biomedich-632	242	12	,	,	PUNCT
biomedich-632	242	13	guha	guha	PROPN
biomedich-632	242	14	,	,	PUNCT
biomedich-632	242	15	et	et	PROPN
biomedich-632	242	16	al	al	PROPN
biomedich-632	242	17	.	.	PROPN
biomedich-632	242	18	(	(	PUNCT
biomedich-632	242	19	2020	2020	NUM
biomedich-632	242	20	)	)	PUNCT
biomedich-632	242	21	.	.	PUNCT
biomedich-632	243	1	local	local	ADJ
biomedich-632	243	2	production	production	NOUN
biomedich-632	243	3	of	of	ADP
biomedich-632	243	4	osteoprotegerin	osteoprotegerin	NOUN
biomedich-632	243	5	by	by	ADP
biomedich-632	243	6	osteoblasts	osteoblast	NOUN
biomedich-632	243	7	suppresses	suppress	VERB
biomedich-632	243	8	bone	bone	NOUN
biomedich-632	243	9	resorption	resorption	NOUN
biomedich-632	243	10	.	.	PUNCT
biomedich-632	244	1	cell	cell	NOUN
biomedich-632	244	2	reports	report	NOUN
biomedich-632	244	3	,	,	PUNCT
biomedich-632	244	4	32(10	32(10	NUM
biomedich-632	244	5	)	)	PUNCT
biomedich-632	244	6	.	.	PUNCT
biomedich-632	245	1	cho	cho	PROPN
biomedich-632	245	2	,	,	PUNCT
biomedich-632	245	3	y.	y.	PROPN
biomedich-632	245	4	e.	e.	PROPN
biomedich-632	245	5	,	,	PUNCT
biomedich-632	245	6	&	&	CCONJ
biomedich-632	245	7	kwun	kwun	PROPN
biomedich-632	245	8	,	,	PUNCT
biomedich-632	245	9	i.	i.	PROPN
biomedich-632	245	10	s.	s.	PROPN
biomedich-632	245	11	(	(	PUNCT
biomedich-632	245	12	2018	2018	NUM
biomedich-632	245	13	)	)	PUNCT
biomedich-632	245	14	.	.	PUNCT
biomedich-632	246	1	zinc	zinc	NOUN
biomedich-632	246	2	upregulates	upregulate	VERB
biomedich-632	246	3	bone	bone	NOUN
biomedich-632	246	4	-	-	PUNCT
biomedich-632	246	5	specific	specific	ADJ
biomedich-632	246	6	transcription	transcription	NOUN
biomedich-632	246	7	factor	factor	NOUN
biomedich-632	246	8	runx2	runx2	NOUN
biomedich-632	246	9	expression	expression	NOUN
biomedich-632	246	10	via	via	ADP
biomedich-632	246	11	bmp-2	bmp-2	VERB
biomedich-632	246	12	signaling	signaling	ADJ
biomedich-632	246	13	and	and	CCONJ
biomedich-632	246	14	smad-1	smad-1	PROPN
biomedich-632	246	15	phosphorylation	phosphorylation	NOUN
biomedich-632	246	16	in	in	ADP
biomedich-632	246	17	osteoblasts	osteoblast	NOUN
biomedich-632	246	18	.	.	PUNCT
biomedich-632	247	1	journal	journal	NOUN
biomedich-632	247	2	of	of	ADP
biomedich-632	247	3	nutrition	nutrition	NOUN
biomedich-632	247	4	and	and	CCONJ
biomedich-632	247	5	health	health	NOUN
biomedich-632	247	6	,	,	PUNCT
biomedich-632	247	7	51(1	51(1	NUM
biomedich-632	247	8	)	)	PUNCT
biomedich-632	247	9	,	,	PUNCT
biomedich-632	247	10	23	23	NUM
biomedich-632	247	11	-	-	SYM
biomedich-632	247	12	30	30	NUM
biomedich-632	247	13	.	.	PUNCT
biomedich-632	248	1	cho	cho	PROPN
biomedich-632	248	2	,	,	PUNCT
biomedich-632	248	3	y.	y.	PROPN
biomedich-632	248	4	e.	e.	PROPN
biomedich-632	248	5	,	,	PUNCT
biomedich-632	248	6	&	&	CCONJ
biomedich-632	248	7	kwun	kwun	PROPN
biomedich-632	248	8	,	,	PUNCT
biomedich-632	248	9	i.	i.	PROPN
biomedich-632	248	10	s.	s.	PROPN
biomedich-632	248	11	(	(	PUNCT
biomedich-632	248	12	2018	2018	NUM
biomedich-632	248	13	)	)	PUNCT
biomedich-632	248	14	.	.	PUNCT
biomedich-632	249	1	zinc	zinc	NOUN
biomedich-632	249	2	upregulates	upregulate	VERB
biomedich-632	249	3	bone	bone	NOUN
biomedich-632	249	4	-	-	PUNCT
biomedich-632	249	5	specific	specific	ADJ
biomedich-632	249	6	transcription	transcription	NOUN
biomedich-632	249	7	factor	factor	NOUN
biomedich-632	249	8	runx2	runx2	NOUN
biomedich-632	249	9	expression	expression	NOUN
biomedich-632	249	10	via	via	ADP
biomedich-632	249	11	bmp-2	bmp-2	VERB
biomedich-632	249	12	signaling	signaling	ADJ
biomedich-632	249	13	and	and	CCONJ
biomedich-632	249	14	smad-1	smad-1	PROPN
biomedich-632	249	15	phosphorylation	phosphorylation	NOUN
biomedich-632	249	16	in	in	ADP
biomedich-632	249	17	osteoblasts	osteoblast	NOUN
biomedich-632	249	18	.	.	PUNCT
biomedich-632	250	1	journal	journal	NOUN
biomedich-632	250	2	of	of	ADP
biomedich-632	250	3	nutrition	nutrition	NOUN
biomedich-632	250	4	and	and	CCONJ
biomedich-632	250	5	health	health	NOUN
biomedich-632	250	6	,	,	PUNCT
biomedich-632	250	7	51(1	51(1	NUM
biomedich-632	250	8	)	)	PUNCT
biomedich-632	250	9	,	,	PUNCT
biomedich-632	250	10	23	23	NUM
biomedich-632	250	11	-	-	SYM
biomedich-632	250	12	30	30	NUM
biomedich-632	250	13	.	.	PUNCT
biomedich-632	251	1	de	de	X
biomedich-632	251	2	loos	loos	PROPN
biomedich-632	251	3	,	,	PUNCT
biomedich-632	251	4	d.	d.	PROPN
biomedich-632	251	5	d.	d.	PROPN
biomedich-632	251	6	,	,	PUNCT
biomedich-632	251	7	lourijsen	lourijsen	PROPN
biomedich-632	251	8	,	,	PUNCT
biomedich-632	251	9	e.	e.	PROPN
biomedich-632	251	10	s.	s.	PROPN
biomedich-632	251	11	,	,	PUNCT
biomedich-632	251	12	wildeman	wildeman	NOUN
biomedich-632	251	13	,	,	PUNCT
biomedich-632	251	14	m.	m.	NOUN
biomedich-632	251	15	a.	a.	PROPN
biomedich-632	251	16	,	,	PUNCT
biomedich-632	251	17	et	et	PROPN
biomedich-632	251	18	al	al	PROPN
biomedich-632	251	19	.	.	PROPN
biomedich-632	252	1	(	(	PUNCT
biomedich-632	252	2	2019	2019	NUM
biomedich-632	252	3	)	)	PUNCT
biomedich-632	252	4	.	.	PUNCT
biomedich-632	253	1	prevalence	prevalence	NOUN
biomedich-632	253	2	of	of	ADP
biomedich-632	253	3	chronic	chronic	ADJ
biomedich-632	253	4	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	253	5	in	in	ADP
biomedich-632	253	6	the	the	DET
biomedich-632	253	7	general	general	ADJ
biomedich-632	253	8	population	population	NOUN
biomedich-632	253	9	based	base	VERB
biomedich-632	253	10	on	on	ADP
biomedich-632	253	11	sinus	sinus	NOUN
biomedich-632	253	12	radiology	radiology	NOUN
biomedich-632	253	13	and	and	CCONJ
biomedich-632	253	14	symptomatology	symptomatology	NOUN
biomedich-632	253	15	.	.	PUNCT
biomedich-632	253	16	journal	journal	PROPN
biomedich-632	253	17	of	of	ADP
biomedich-632	253	18	allergy	allergy	PROPN
biomedich-632	253	19	and	and	CCONJ
biomedich-632	253	20	clinical	clinical	ADJ
biomedich-632	253	21	immunology	immunology	NOUN
biomedich-632	253	22	,	,	PUNCT
biomedich-632	253	23	143(3	143(3	NUM
biomedich-632	253	24	)	)	PUNCT
biomedich-632	253	25	,	,	PUNCT
biomedich-632	253	26	1207	1207	NUM
biomedich-632	253	27	-	-	SYM
biomedich-632	253	28	1214	1214	NUM
biomedich-632	253	29	.	.	PUNCT
biomedich-632	254	1	dhingra	dhingra	PROPN
biomedich-632	254	2	,	,	PUNCT
biomedich-632	254	3	p.l	p.l	PROPN
biomedich-632	254	4	.	.	PROPN
biomedich-632	254	5	&	&	CCONJ
biomedich-632	254	6	dhingra	dhingra	PROPN
biomedich-632	254	7	,	,	PUNCT
biomedich-632	254	8	s.	s.	PROPN
biomedich-632	254	9	(	(	PUNCT
biomedich-632	254	10	2021	2021	NUM
biomedich-632	254	11	)	)	PUNCT
biomedich-632	254	12	.	.	PUNCT
biomedich-632	255	1	diseases	disease	NOUN
biomedich-632	255	2	of	of	ADP
biomedich-632	255	3	ear	ear	NOUN
biomedich-632	255	4	,	,	PUNCT
biomedich-632	255	5	nose	nose	NOUN
biomedich-632	255	6	&	&	CCONJ
biomedich-632	255	7	throat	throat	NOUN
biomedich-632	255	8	and	and	CCONJ
biomedich-632	255	9	head	head	NOUN
biomedich-632	255	10	&	&	CCONJ
biomedich-632	255	11	neck	neck	PROPN
biomedich-632	255	12	surgery	surgery	NOUN
biomedich-632	255	13	-	-	PUNCT
biomedich-632	255	14	e	e	NOUN
biomedich-632	255	15	-	-	NOUN
biomedich-632	255	16	book	book	NOUN
biomedich-632	255	17	.	.	PUNCT
biomedich-632	256	1	elsevier	elsevier	PROPN
biomedich-632	256	2	health	health	PROPN
biomedich-632	256	3	sciences	sciences	PROPN
biomedich-632	256	4	.	.	PUNCT
biomedich-632	257	1	new	new	ADJ
biomedich-632	257	2	delhi	delhi	PROPN
biomedich-632	257	3	.	.	PUNCT
biomedich-632	258	1	ference	ference	PROPN
biomedich-632	258	2	,	,	PUNCT
biomedich-632	258	3	e.	e.	PROPN
biomedich-632	258	4	h.	h.	PROPN
biomedich-632	258	5	,	,	PUNCT
biomedich-632	258	6	tan	tan	PROPN
biomedich-632	258	7	,	,	PUNCT
biomedich-632	258	8	b.	b.	PROPN
biomedich-632	258	9	k.	k.	PROPN
biomedich-632	258	10	,	,	PUNCT
biomedich-632	258	11	hulse	hulse	PROPN
biomedich-632	258	12	,	,	PUNCT
biomedich-632	258	13	k.	k.	PROPN
biomedich-632	258	14	e.	e.	PROPN
biomedich-632	258	15	,	,	PUNCT
biomedich-632	258	16	et	et	PROPN
biomedich-632	258	17	al	al	PROPN
biomedich-632	258	18	.	.	PUNCT
biomedich-632	258	19	(	(	PUNCT
biomedich-632	258	20	2015	2015	NUM
biomedich-632	258	21	)	)	PUNCT
biomedich-632	258	22	.	.	PUNCT
biomedich-632	259	1	commentary	commentary	NOUN
biomedich-632	259	2	on	on	ADP
biomedich-632	259	3	gender	gender	NOUN
biomedich-632	259	4	differences	difference	NOUN
biomedich-632	259	5	in	in	ADP
biomedich-632	259	6	prevalence	prevalence	NOUN
biomedich-632	259	7	,	,	PUNCT
biomedich-632	259	8	treatment	treatment	NOUN
biomedich-632	259	9	,	,	PUNCT
biomedich-632	259	10	and	and	CCONJ
biomedich-632	259	11	quality	quality	NOUN
biomedich-632	259	12	of	of	ADP
biomedich-632	259	13	life	life	NOUN
biomedich-632	259	14	of	of	ADP
biomedich-632	259	15	patients	patient	NOUN
biomedich-632	259	16	with	with	ADP
biomedich-632	259	17	chronic	chronic	ADJ
biomedich-632	259	18	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	259	19	.	.	PUNCT
biomedich-632	260	1	allergy	allergy	PROPN
biomedich-632	260	2	&	&	CCONJ
biomedich-632	260	3	rhinology	rhinology	PROPN
biomedich-632	260	4	,	,	PUNCT
biomedich-632	260	5	6(2	6(2	NUM
biomedich-632	260	6	)	)	PUNCT
biomedich-632	260	7	,	,	PUNCT
biomedich-632	260	8	ar-2015	ar-2015	PROPN
biomedich-632	260	9	.	.	PUNCT
biomedich-632	261	1	fokkens	fokkens	PROPN
biomedich-632	261	2	,	,	PUNCT
biomedich-632	261	3	w.	w.	PROPN
biomedich-632	261	4	j.	j.	PROPN
biomedich-632	261	5	,	,	PUNCT
biomedich-632	261	6	lund	lund	PROPN
biomedich-632	261	7	,	,	PUNCT
biomedich-632	261	8	v.	v.	PROPN
biomedich-632	261	9	i.	i.	PROPN
biomedich-632	261	10	,	,	PUNCT
biomedich-632	261	11	mullol	mullol	PROPN
biomedich-632	261	12	,	,	PUNCT
biomedich-632	261	13	j.	j.	PROPN
biomedich-632	261	14	,	,	PUNCT
biomedich-632	261	15	et	et	PROPN
biomedich-632	261	16	al	al	PROPN
biomedich-632	261	17	.	.	PUNCT
biomedich-632	262	1	(	(	PUNCT
biomedich-632	262	2	2012	2012	NUM
biomedich-632	262	3	)	)	PUNCT
biomedich-632	262	4	.	.	PUNCT
biomedich-632	263	1	european	european	ADJ
biomedich-632	263	2	position	position	NOUN
biomedich-632	263	3	paper	paper	NOUN
biomedich-632	263	4	on	on	ADP
biomedich-632	263	5	rhinosinusitis	rhinosinusitis	PROPN
biomedich-632	263	6	and	and	CCONJ
biomedich-632	263	7	nasal	nasal	ADJ
biomedich-632	263	8	polyps	polyp	NOUN
biomedich-632	263	9	2012	2012	NUM
biomedich-632	263	10	.	.	PUNCT
biomedich-632	264	1	rhinology	rhinology	NOUN
biomedich-632	264	2	,	,	PUNCT
biomedich-632	264	3	50(suppl	50(suppl	NUM
biomedich-632	264	4	.	.	NOUN
biomedich-632	264	5	23	23	NUM
biomedich-632	264	6	)	)	PUNCT
biomedich-632	264	7	,	,	PUNCT
biomedich-632	264	8	1	1	NUM
biomedich-632	264	9	-	-	SYM
biomedich-632	264	10	298	298	NUM
biomedich-632	264	11	.	.	PUNCT
biomedich-632	265	1	fokkens	fokkens	PROPN
biomedich-632	265	2	,	,	PUNCT
biomedich-632	265	3	w.	w.	PROPN
biomedich-632	265	4	j.	j.	PROPN
biomedich-632	265	5	,	,	PUNCT
biomedich-632	265	6	lund	lund	PROPN
biomedich-632	265	7	,	,	PUNCT
biomedich-632	265	8	v.	v.	PROPN
biomedich-632	265	9	j.	j.	PROPN
biomedich-632	265	10	,	,	PUNCT
biomedich-632	265	11	hopkins	hopkins	PROPN
biomedich-632	265	12	,	,	PUNCT
biomedich-632	265	13	c.	c.	PROPN
biomedich-632	265	14	,	,	PUNCT
biomedich-632	265	15	et	et	PROPN
biomedich-632	265	16	al	al	PROPN
biomedich-632	265	17	.	.	PROPN
biomedich-632	265	18	(	(	PUNCT
biomedich-632	265	19	2020	2020	NUM
biomedich-632	265	20	)	)	PUNCT
biomedich-632	265	21	.	.	PUNCT
biomedich-632	266	1	european	european	ADJ
biomedich-632	266	2	position	position	NOUN
biomedich-632	266	3	paper	paper	NOUN
biomedich-632	266	4	on	on	ADP
biomedich-632	266	5	rhinosinusitis	rhinosinusitis	PROPN
biomedich-632	266	6	and	and	CCONJ
biomedich-632	266	7	nasal	nasal	ADJ
biomedich-632	266	8	polyps	polyp	NOUN
biomedich-632	266	9	2020	2020	NUM
biomedich-632	266	10	.	.	PUNCT
biomedich-632	267	1	hulse	hulse	PROPN
biomedich-632	267	2	,	,	PUNCT
biomedich-632	267	3	k.	k.	PROPN
biomedich-632	267	4	e.	e.	PROPN
biomedich-632	267	5	,	,	PUNCT
biomedich-632	267	6	stevens	stevens	PROPN
biomedich-632	267	7	,	,	PUNCT
biomedich-632	267	8	w.	w.	PROPN
biomedich-632	267	9	w.	w.	PROPN
biomedich-632	267	10	,	,	PUNCT
biomedich-632	267	11	tan	tan	PROPN
biomedich-632	267	12	,	,	PUNCT
biomedich-632	267	13	b.	b.	PROPN
biomedich-632	267	14	k.	k.	PROPN
biomedich-632	267	15	,	,	PUNCT
biomedich-632	267	16	et	et	PROPN
biomedich-632	267	17	al	al	PROPN
biomedich-632	267	18	.	.	PUNCT
biomedich-632	268	1	(	(	PUNCT
biomedich-632	268	2	2014	2014	NUM
biomedich-632	268	3	)	)	PUNCT
biomedich-632	268	4	.	.	PUNCT
biomedich-632	269	1	sexspecific	sexspecific	ADJ
biomedich-632	269	2	differences	difference	NOUN
biomedich-632	269	3	in	in	ADP
biomedich-632	269	4	disease	disease	NOUN
biomedich-632	269	5	severity	severity	NOUN
biomedich-632	269	6	in	in	ADP
biomedich-632	269	7	patients	patient	NOUN
biomedich-632	269	8	with	with	ADP
biomedich-632	269	9	chronic	chronic	ADJ
biomedich-632	269	10	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	269	11	with	with	ADP
biomedich-632	269	12	nasal	nasal	ADJ
biomedich-632	269	13	polyps	polyp	NOUN
biomedich-632	269	14	.	.	PUNCT
biomedich-632	270	1	journal	journal	PROPN
biomedich-632	270	2	of	of	ADP
biomedich-632	270	3	allergy	allergy	NOUN
biomedich-632	270	4	and	and	CCONJ
biomedich-632	270	5	clinical	clinical	ADJ
biomedich-632	270	6	immunology	immunology	NOUN
biomedich-632	270	7	,	,	PUNCT
biomedich-632	270	8	133(2	133(2	NUM
biomedich-632	270	9	)	)	PUNCT
biomedich-632	270	10	,	,	PUNCT
biomedich-632	270	11	ab169	ab169	PROPN
biomedich-632	270	12	.	.	PUNCT
biomedich-632	271	1	khalmuratova	khalmuratova	PROPN
biomedich-632	271	2	,	,	PUNCT
biomedich-632	271	3	r.	r.	PROPN
biomedich-632	271	4	,	,	PUNCT
biomedich-632	271	5	shin	shin	PROPN
biomedich-632	271	6	,	,	PUNCT
biomedich-632	271	7	h.	h.	PROPN
biomedich-632	271	8	w.	w.	PROPN
biomedich-632	271	9	,	,	PUNCT
biomedich-632	271	10	kim	kim	PROPN
biomedich-632	271	11	,	,	PUNCT
biomedich-632	271	12	d.	d.	PROPN
biomedich-632	271	13	w.	w.	PROPN
biomedich-632	271	14	,	,	PUNCT
biomedich-632	271	15	et	et	PROPN
biomedich-632	271	16	al	al	PROPN
biomedich-632	271	17	.	.	PROPN
biomedich-632	271	18	(	(	PUNCT
biomedich-632	271	19	2019	2019	NUM
biomedich-632	271	20	)	)	PUNCT
biomedich-632	271	21	.	.	PUNCT
biomedich-632	272	1	interleukin	interleukin	NOUN
biomedich-632	272	2	(	(	PUNCT
biomedich-632	272	3	il)-13	il)-13	PROPN
biomedich-632	272	4	and	and	CCONJ
biomedich-632	272	5	il-17a	il-17a	PROPN
biomedich-632	272	6	contribute	contribute	VERB
biomedich-632	272	7	to	to	ADP
biomedich-632	272	8	neo	neo	NOUN
biomedich-632	272	9	-	-	NOUN
biomedich-632	272	10	osteogenesis	osteogenesis	NOUN
biomedich-632	272	11	in	in	ADP
biomedich-632	272	12	chronic	chronic	ADJ
biomedich-632	272	13	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	272	14	by	by	ADP
biomedich-632	272	15	inducing	induce	VERB
biomedich-632	272	16	runx2	runx2	NOUN
biomedich-632	272	17	.	.	PUNCT
biomedich-632	273	1	ebiomedicine	ebiomedicine	PROPN
biomedich-632	273	2	,	,	PUNCT
biomedich-632	273	3	46	46	NUM
biomedich-632	273	4	,	,	PUNCT
biomedich-632	273	5	330	330	NUM
biomedich-632	273	6	-	-	SYM
biomedich-632	273	7	341	341	NUM
biomedich-632	273	8	.	.	PUNCT
biomedich-632	274	1	kim	kim	PROPN
biomedich-632	274	2	,	,	PUNCT
biomedich-632	274	3	j.	j.	PROPN
biomedich-632	274	4	y.	y.	PROPN
biomedich-632	274	5	,	,	PUNCT
biomedich-632	274	6	lim	lim	PROPN
biomedich-632	274	7	,	,	PUNCT
biomedich-632	274	8	s.	s.	PROPN
biomedich-632	274	9	,	,	PUNCT
biomedich-632	274	10	lim	lim	PROPN
biomedich-632	274	11	,	,	PUNCT
biomedich-632	274	12	h.	h.	PROPN
biomedich-632	274	13	s.	s.	PROPN
biomedich-632	274	14	,	,	PUNCT
biomedich-632	274	15	et	et	PROPN
biomedich-632	274	16	al	al	PROPN
biomedich-632	274	17	.	.	PUNCT
biomedich-632	274	18	(	(	PUNCT
biomedich-632	274	19	2021	2021	NUM
biomedich-632	274	20	)	)	PUNCT
biomedich-632	274	21	.	.	PUNCT
biomedich-632	275	1	bone	bone	PROPN
biomedich-632	275	2	morphogenetic	morphogenetic	ADJ
biomedich-632	275	3	protein-2	protein-2	PROPN
biomedich-632	275	4	as	as	ADP
biomedich-632	275	5	a	a	DET
biomedich-632	275	6	novel	novel	NOUN
biomedich-632	275	7	biomarker	biomarker	NOUN
biomedich-632	275	8	for	for	ADP
biomedich-632	275	9	refractory	refractory	NOUN
biomedich-632	275	10	chronic	chronic	NOUN
biomedich-632	275	11	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	275	12	with	with	ADP
biomedich-632	275	13	nasal	nasal	ADJ
biomedich-632	275	14	polyps	polyp	NOUN
biomedich-632	275	15	.	.	PUNCT
biomedich-632	276	1	journal	journal	PROPN
biomedich-632	276	2	of	of	ADP
biomedich-632	276	3	allergy	allergy	NOUN
biomedich-632	276	4	and	and	CCONJ
biomedich-632	276	5	clinical	clinical	ADJ
biomedich-632	276	6	immunology	immunology	NOUN
biomedich-632	276	7	,	,	PUNCT
biomedich-632	276	8	148(2	148(2	NUM
biomedich-632	276	9	)	)	PUNCT
biomedich-632	276	10	,	,	PUNCT
biomedich-632	276	11	461	461	NUM
biomedich-632	276	12	-	-	SYM
biomedich-632	276	13	472	472	NUM
biomedich-632	276	14	.	.	PUNCT
biomedich-632	277	1	kong	kong	PROPN
biomedich-632	277	2	,	,	PUNCT
biomedich-632	277	3	i.	i.	PROPN
biomedich-632	277	4	g.	g.	PROPN
biomedich-632	277	5	,	,	PUNCT
biomedich-632	277	6	kim	kim	PROPN
biomedich-632	277	7	,	,	PUNCT
biomedich-632	277	8	d.	d.	PROPN
biomedich-632	277	9	k.	k.	PROPN
biomedich-632	277	10	,	,	PUNCT
biomedich-632	277	11	eun	eun	PROPN
biomedich-632	277	12	,	,	PUNCT
biomedich-632	277	13	k.	k.	PROPN
biomedich-632	277	14	m.	m.	PROPN
biomedich-632	277	15	,	,	PUNCT
biomedich-632	277	16	et	et	PROPN
biomedich-632	277	17	al	al	PROPN
biomedich-632	277	18	.	.	PROPN
biomedich-632	277	19	(	(	PUNCT
biomedich-632	277	20	2020	2020	NUM
biomedich-632	277	21	)	)	PUNCT
biomedich-632	277	22	.	.	PUNCT
biomedich-632	278	1	receptor	receptor	NOUN
biomedich-632	278	2	activator	activator	NOUN
biomedich-632	278	3	of	of	ADP
biomedich-632	278	4	nuclear	nuclear	ADJ
biomedich-632	278	5	factor	factor	NOUN
biomedich-632	278	6	κb	κb	PROPN
biomedich-632	278	7	ligand	ligand	NOUN
biomedich-632	278	8	is	be	AUX
biomedich-632	278	9	a	a	DET
biomedich-632	278	10	biomarker	biomarker	NOUN
biomedich-632	278	11	for	for	ADP
biomedich-632	278	12	osteitis	osteitis	NOUN
biomedich-632	278	13	of	of	ADP
biomedich-632	278	14	chronic	chronic	ADJ
biomedich-632	278	15	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	278	16	.	.	PUNCT
biomedich-632	279	1	in	in	ADP
biomedich-632	279	2	international	international	ADJ
biomedich-632	279	3	forum	forum	PROPN
biomedich-632	279	4	of	of	ADP
biomedich-632	279	5	allergy	allergy	PROPN
biomedich-632	279	6	&	&	CCONJ
biomedich-632	279	7	rhinology	rhinology	PROPN
biomedich-632	279	8	,	,	PUNCT
biomedich-632	279	9	10(3	10(3	NUM
biomedich-632	279	10	)	)	PUNCT
biomedich-632	279	11	pp	pp	ADV
biomedich-632	279	12	.	.	PUNCT
biomedich-632	280	1	364	364	NUM
biomedich-632	280	2	-	-	SYM
biomedich-632	280	3	373	373	NUM
biomedich-632	280	4	.	.	PUNCT
biomedich-632	281	1	leung	leung	PROPN
biomedich-632	281	2	,	,	PUNCT
biomedich-632	281	3	n.	n.	PROPN
biomedich-632	281	4	,	,	PUNCT
biomedich-632	281	5	mawby	mawby	PROPN
biomedich-632	281	6	,	,	PUNCT
biomedich-632	281	7	t.	t.	PROPN
biomedich-632	281	8	a.	a.	PROPN
biomedich-632	281	9	r.	r.	PROPN
biomedich-632	281	10	,	,	PUNCT
biomedich-632	281	11	turner	turner	PROPN
biomedich-632	281	12	,	,	PUNCT
biomedich-632	281	13	h.	h.	PROPN
biomedich-632	281	14	,	,	PUNCT
biomedich-632	281	15	&	&	CCONJ
biomedich-632	281	16	qureishi	qureishi	PROPN
biomedich-632	281	17	,	,	PUNCT
biomedich-632	281	18	a.	a.	NOUN
biomedich-632	281	19	(	(	PUNCT
biomedich-632	281	20	2016	2016	NUM
biomedich-632	281	21	)	)	PUNCT
biomedich-632	281	22	.	.	PUNCT
biomedich-632	282	1	osteitis	osteitis	NOUN
biomedich-632	282	2	and	and	CCONJ
biomedich-632	282	3	chronic	chronic	ADJ
biomedich-632	282	4	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	282	5	:	:	PUNCT
biomedich-632	282	6	a	a	DET
biomedich-632	282	7	review	review	NOUN
biomedich-632	282	8	of	of	ADP
biomedich-632	282	9	the	the	DET
biomedich-632	282	10	current	current	ADJ
biomedich-632	282	11	literature	literature	NOUN
biomedich-632	282	12	.	.	PUNCT
biomedich-632	283	1	european	european	ADJ
biomedich-632	283	2	archives	archive	NOUN
biomedich-632	283	3	of	of	ADP
biomedich-632	283	4	oto	oto	NOUN
biomedich-632	283	5	-	-	PUNCT
biomedich-632	283	6	rhino	rhino	NOUN
biomedich-632	283	7	-	-	PUNCT
biomedich-632	283	8	laryngology	laryngology	NOUN
biomedich-632	283	9	,	,	PUNCT
biomedich-632	283	10	273	273	NUM
biomedich-632	283	11	,	,	PUNCT
biomedich-632	283	12	2917	2917	NUM
biomedich-632	283	13	-	-	SYM
biomedich-632	283	14	2923	2923	NUM
biomedich-632	283	15	.	.	PUNCT
biomedich-632	284	1	mehta	mehta	PROPN
biomedich-632	284	2	,	,	PUNCT
biomedich-632	284	3	v.	v.	PROPN
biomedich-632	284	4	,	,	PUNCT
biomedich-632	284	5	campeau	campeau	PROPN
biomedich-632	284	6	,	,	PUNCT
biomedich-632	284	7	n.	n.	PROPN
biomedich-632	284	8	g.	g.	PROPN
biomedich-632	284	9	,	,	PUNCT
biomedich-632	284	10	kita	kita	PROPN
biomedich-632	284	11	,	,	PUNCT
biomedich-632	284	12	h.	h.	PROPN
biomedich-632	284	13	,	,	PUNCT
biomedich-632	284	14	et	et	PROPN
biomedich-632	284	15	al	al	PROPN
biomedich-632	284	16	.	.	PUNCT
biomedich-632	284	17	(	(	PUNCT
biomedich-632	284	18	2008	2008	NUM
biomedich-632	284	19	)	)	PUNCT
biomedich-632	284	20	.	.	PUNCT
biomedich-632	285	1	blood	blood	NOUN
biomedich-632	285	2	and	and	CCONJ
biomedich-632	285	3	sputum	sputum	NOUN
biomedich-632	285	4	eosinophil	eosinophil	ADJ
biomedich-632	285	5	levels	level	NOUN
biomedich-632	285	6	in	in	ADP
biomedich-632	285	7	asthma	asthma	NOUN
biomedich-632	285	8	and	and	CCONJ
biomedich-632	285	9	their	their	PRON
biomedich-632	285	10	relationship	relationship	NOUN
biomedich-632	285	11	to	to	ADP
biomedich-632	285	12	sinus	sinus	NOUN
biomedich-632	285	13	computed	compute	VERB
biomedich-632	285	14	tomographic	tomographic	ADJ
biomedich-632	285	15	findings	finding	NOUN
biomedich-632	285	16	.	.	PUNCT
biomedich-632	286	1	in	in	ADP
biomedich-632	286	2	mayo	mayo	PROPN
biomedich-632	286	3	clinic	clinic	PROPN
biomedich-632	286	4	proceedings	proceeding	NOUN
biomedich-632	286	5	,	,	PUNCT
biomedich-632	286	6	83(6	83(6	NOUN
biomedich-632	286	7	)	)	PUNCT
biomedich-632	286	8	pp	pp	ADV
biomedich-632	286	9	.	.	PUNCT
biomedich-632	287	1	671	671	NUM
biomedich-632	287	2	-	-	SYM
biomedich-632	287	3	678	678	NUM
biomedich-632	287	4	)	)	PUNCT
biomedich-632	287	5	.	.	PUNCT
biomedich-632	288	1	elsevier	elsevier	PROPN
biomedich-632	288	2	.	.	PUNCT
biomedich-632	289	1	paulini	paulini	PROPN
biomedich-632	289	2	,	,	PUNCT
biomedich-632	289	3	m.	m.	NOUN
biomedich-632	289	4	,	,	PUNCT
biomedich-632	289	5	camal	camal	NOUN
biomedich-632	289	6	ruggieri	ruggieri	NOUN
biomedich-632	289	7	,	,	PUNCT
biomedich-632	289	8	i.	i.	PROPN
biomedich-632	289	9	n.	n.	PROPN
biomedich-632	289	10	,	,	PUNCT
biomedich-632	289	11	ramallo	ramallo	PROPN
biomedich-632	289	12	,	,	PUNCT
biomedich-632	289	13	m.	m.	NOUN
biomedich-632	289	14	,	,	PUNCT
biomedich-632	289	15	et	et	PROPN
biomedich-632	289	16	al	al	PROPN
biomedich-632	289	17	.	.	PROPN
biomedich-632	289	18	(	(	PUNCT
biomedich-632	289	19	2021	2021	NUM
biomedich-632	289	20	)	)	PUNCT
biomedich-632	289	21	.	.	PUNCT
biomedich-632	290	1	recombinant	recombinant	ADJ
biomedich-632	290	2	proteins	protein	NOUN
biomedich-632	290	3	-	-	PUNCT
biomedich-632	290	4	based	base	VERB
biomedich-632	290	5	strategies	strategy	NOUN
biomedich-632	290	6	in	in	ADP
biomedich-632	290	7	bone	bone	NOUN
biomedich-632	290	8	tissue	tissue	NOUN
biomedich-632	290	9	engineering	engineering	NOUN
biomedich-632	290	10	.	.	PUNCT
biomedich-632	291	1	biomolecules	biomolecule	NOUN
biomedich-632	291	2	,	,	PUNCT
biomedich-632	291	3	12(1	12(1	NUM
biomedich-632	291	4	)	)	PUNCT
biomedich-632	291	5	,	,	PUNCT
biomedich-632	291	6	3	3	X
biomedich-632	291	7	.	.	PUNCT
biomedich-632	291	8	russell	russell	PROPN
biomedich-632	291	9	a.	a.	PROPN
biomedich-632	291	10	faust	faust	PROPN
biomedich-632	291	11	.	.	PUNCT
biomedich-632	292	1	(	(	PUNCT
biomedich-632	292	2	2010	2010	NUM
biomedich-632	292	3	)	)	PUNCT
biomedich-632	292	4	.	.	PUNCT
biomedich-632	293	1	development	development	NOUN
biomedich-632	293	2	of	of	ADP
biomedich-632	293	3	the	the	DET
biomedich-632	293	4	paranasal	paranasal	ADJ
biomedich-632	293	5	sinuses	sinus	NOUN
biomedich-632	293	6	in	in	ADP
biomedich-632	293	7	children	child	NOUN
biomedich-632	293	8	.	.	PUNCT
biomedich-632	294	1	in	in	ADP
biomedich-632	294	2	:	:	PUNCT
biomedich-632	294	3	ask	ask	VERB
biomedich-632	294	4	the	the	DET
biomedich-632	294	5	boogor	boogor	ADJ
biomedich-632	294	6	doctor	doctor	NOUN
biomedich-632	294	7	.	.	PUNCT
biomedich-632	295	1	snidvongs	snidvong	NOUN
biomedich-632	295	2	,	,	PUNCT
biomedich-632	295	3	k.	k.	PROPN
biomedich-632	295	4	,	,	PUNCT
biomedich-632	295	5	sacks	sacks	PROPN
biomedich-632	295	6	,	,	PUNCT
biomedich-632	295	7	r.	r.	PROPN
biomedich-632	295	8	,	,	PUNCT
biomedich-632	295	9	&	&	CCONJ
biomedich-632	295	10	harvey	harvey	PROPN
biomedich-632	295	11	,	,	PUNCT
biomedich-632	295	12	r.	r.	PROPN
biomedich-632	295	13	j.	j.	PROPN
biomedich-632	295	14	(	(	PUNCT
biomedich-632	295	15	2019	2019	NUM
biomedich-632	295	16	)	)	PUNCT
biomedich-632	295	17	.	.	PUNCT
biomedich-632	296	1	osteitis	osteitis	NOUN
biomedich-632	296	2	in	in	ADP
biomedich-632	296	3	chronic	chronic	ADJ
biomedich-632	296	4	rhinosinusitis	rhinosinusitis	NOUN
biomedich-632	296	5	.	.	PUNCT
biomedich-632	297	1	current	current	ADJ
biomedich-632	297	2	allergy	allergy	NOUN
biomedich-632	297	3	and	and	CCONJ
biomedich-632	297	4	asthma	asthma	NOUN
biomedich-632	297	5	reports	report	NOUN
biomedich-632	297	6	,	,	PUNCT
biomedich-632	297	7	19	19	NUM
biomedich-632	297	8	,	,	PUNCT
biomedich-632	297	9	1	1	NUM
biomedich-632	297	10	-	-	SYM
biomedich-632	297	11	10	10	NUM
biomedich-632	297	12	.	.	PUNCT
biomedich-632	298	1	soepardi	soepardi	PROPN
biomedich-632	298	2	,	,	PUNCT
biomedich-632	298	3	e.	e.	PROPN
biomedich-632	298	4	a.	a.	PROPN
biomedich-632	298	5	,	,	PUNCT
biomedich-632	298	6	&	&	CCONJ
biomedich-632	298	7	iskandar	iskandar	PROPN
biomedich-632	298	8	,	,	PUNCT
biomedich-632	298	9	n.	n.	PROPN
biomedich-632	298	10	(	(	PUNCT
biomedich-632	298	11	2001	2001	NUM
biomedich-632	298	12	)	)	PUNCT
biomedich-632	298	13	.	.	PUNCT
biomedich-632	299	1	buku	buku	PROPN
biomedich-632	299	2	ajar	ajar	PROPN
biomedich-632	299	3	ilmu	ilmu	PROPN
biomedich-632	299	4	kesehatan	kesehatan	PROPN
biomedich-632	299	5	:	:	PUNCT
biomedich-632	299	6	telinga	telinga	PROPN
biomedich-632	299	7	,	,	PUNCT
biomedich-632	299	8	hidung	hidung	PROPN
biomedich-632	299	9	,	,	PUNCT
biomedich-632	299	10	tenggorok	tenggorok	PROPN
biomedich-632	299	11	,	,	PUNCT
biomedich-632	299	12	kepala	kepala	PROPN
biomedich-632	299	13	leher	leher	PROPN
biomedich-632	299	14	.	.	PUNCT
biomedich-632	300	1	balai	balai	PROPN
biomedich-632	300	2	penerbit	penerbit	PROPN
biomedich-632	300	3	fkui	fkui	PROPN
biomedich-632	300	4	.	.	PUNCT
biomedich-632	301	1	jakarta	jakarta	PROPN
biomedich-632	301	2	.	.	PUNCT
biomedich-632	302	1	zhang	zhang	PROPN
biomedich-632	302	2	,	,	PUNCT
biomedich-632	302	3	y.	y.	PROPN
biomedich-632	302	4	,	,	PUNCT
biomedich-632	302	5	shen	shen	PROPN
biomedich-632	302	6	,	,	PUNCT
biomedich-632	302	7	l.	l.	PROPN
biomedich-632	302	8	,	,	PUNCT
biomedich-632	302	9	mao	mao	PROPN
biomedich-632	302	10	,	,	PUNCT
biomedich-632	302	11	z.	z.	PROPN
biomedich-632	302	12	,	,	PUNCT
biomedich-632	302	13	et	et	PROPN
biomedich-632	302	14	al	al	PROPN
biomedich-632	302	15	.	.	PUNCT
biomedich-632	302	16	(	(	PUNCT
biomedich-632	302	17	2017	2017	NUM
biomedich-632	302	18	)	)	PUNCT
biomedich-632	302	19	.	.	PUNCT
biomedich-632	303	1	icariin	icariin	NOUN
biomedich-632	303	2	enhances	enhance	VERB
biomedich-632	303	3	bone	bone	NOUN
biomedich-632	303	4	repair	repair	NOUN
biomedich-632	303	5	in	in	ADP
biomedich-632	303	6	rabbits	rabbit	NOUN
biomedich-632	303	7	with	with	ADP
biomedich-632	303	8	bone	bone	NOUN
biomedich-632	303	9	infection	infection	NOUN
biomedich-632	303	10	during	during	ADP
biomedich-632	303	11	post	post	ADJ
biomedich-632	303	12	-	-	ADJ
biomedich-632	303	13	infection	infection	ADJ
biomedich-632	303	14	treatment	treatment	NOUN
biomedich-632	303	15	and	and	CCONJ
biomedich-632	303	16	prevents	prevent	VERB
biomedich-632	303	17	inhibition	inhibition	NOUN
biomedich-632	303	18	of	of	ADP
biomedich-632	303	19	osteoblasts	osteoblast	NOUN
biomedich-632	303	20	by	by	ADP
biomedich-632	303	21	vancomycin	vancomycin	PROPN
biomedich-632	303	22	.	.	PUNCT
biomedich-632	304	1	frontiers	frontier	NOUN
biomedich-632	304	2	in	in	ADP
biomedich-632	304	3	pharmacology	pharmacology	NOUN
biomedich-632	304	4	,	,	PUNCT
biomedich-632	304	5	8	8	NUM
biomedich-632	304	6	,	,	PUNCT
biomedich-632	304	7	784	784	NUM
biomedich-632	304	8	.	.	PUNCT