id	sid	tid	token	lemma	pos
biomedich-691	1	1	biology	biology	NOUN
biomedich-691	1	2	,	,	PUNCT
biomedich-691	1	3	medicine	medicine	NOUN
biomedich-691	1	4	,	,	PUNCT
biomedich-691	1	5	&	&	CCONJ
biomedich-691	1	6	natural	natural	ADJ
biomedich-691	1	7	product	product	NOUN
biomedich-691	1	8	chemistry	chemistry	NOUN
biomedich-691	1	9	issn	issn	VERB
biomedich-691	1	10	2089	2089	NUM
biomedich-691	1	11	-	-	SYM
biomedich-691	1	12	6514	6514	NUM
biomedich-691	1	13	(	(	PUNCT
biomedich-691	1	14	paper	paper	NOUN
biomedich-691	1	15	)	)	PUNCT
biomedich-691	1	16	volume	volume	NOUN
biomedich-691	1	17	14	14	NUM
biomedich-691	1	18	,	,	PUNCT
biomedich-691	1	19	number	number	NOUN
biomedich-691	1	20	1	1	NUM
biomedich-691	1	21	,	,	PUNCT
biomedich-691	1	22	april	april	PROPN
biomedich-691	1	23	2025	2025	NUM
biomedich-691	1	24	|	|	ADV
biomedich-691	1	25	pages	page	NOUN
biomedich-691	1	26	:	:	PUNCT
biomedich-691	1	27	199	199	NUM
biomedich-691	1	28	-	-	SYM
biomedich-691	1	29	204	204	NUM
biomedich-691	1	30	|	|	ADV
biomedich-691	1	31	doi	doi	NOUN
biomedich-691	1	32	:	:	PUNCT
biomedich-691	1	33	10.14421	10.14421	NUM
biomedich-691	1	34	/	/	SYM
biomedich-691	1	35	biomedich.2025.141.199	biomedich.2025.141.199	NOUN
biomedich-691	1	36	-	-	PUNCT
biomedich-691	1	37	204	204	NUM
biomedich-691	1	38	issn	issn	PROPN
biomedich-691	1	39	2540	2540	NUM
biomedich-691	1	40	-	-	SYM
biomedich-691	1	41	9328	9328	NUM
biomedich-691	1	42	(	(	PUNCT
biomedich-691	1	43	online	online	ADJ
biomedich-691	1	44	)	)	PUNCT
biomedich-691	1	45	prediction	prediction	NOUN
biomedich-691	1	46	of	of	ADP
biomedich-691	1	47	artocarpus	artocarpus	PROPN
biomedich-691	1	48	altilis	altili	VERB
biomedich-691	1	49	potential	potential	ADJ
biomedich-691	1	50	as	as	ADP
biomedich-691	1	51	an	an	DET
biomedich-691	1	52	anti	anti	ADJ
biomedich-691	1	53	breast	breast	NOUN
biomedich-691	1	54	cancer	cancer	NOUN
biomedich-691	1	55	by	by	ADP
biomedich-691	1	56	inhibiting	inhibit	VERB
biomedich-691	1	57	egfr	egfr	NOUN
biomedich-691	1	58	:	:	PUNCT
biomedich-691	1	59	a	a	DET
biomedich-691	1	60	molecular	molecular	ADJ
biomedich-691	1	61	docking	docking	NOUN
biomedich-691	1	62	study	study	NOUN
biomedich-691	1	63	muhammad	muhammad	PROPN
biomedich-691	1	64	farid	farid	PROPN
biomedich-691	1	65	*	*	PROPN
biomedich-691	1	66	,	,	PUNCT
biomedich-691	1	67	ardestya	ardestya	ADJ
biomedich-691	1	68	rastrani	rastrani	NOUN
biomedich-691	1	69	,	,	PUNCT
biomedich-691	1	70	adinda	adinda	PROPN
biomedich-691	1	71	aulia	aulia	PROPN
biomedich-691	1	72	rahma	rahma	PROPN
biomedich-691	1	73	,	,	PUNCT
biomedich-691	1	74	widya	widya	PROPN
biomedich-691	1	75	aryana	aryana	PROPN
biomedich-691	1	76	ramadhania	ramadhania	PROPN
biomedich-691	1	77	department	department	PROPN
biomedich-691	1	78	of	of	ADP
biomedich-691	1	79	medicine	medicine	NOUN
biomedich-691	1	80	,	,	PUNCT
biomedich-691	1	81	faculty	faculty	NOUN
biomedich-691	1	82	of	of	ADP
biomedich-691	1	83	medicine	medicine	NOUN
biomedich-691	1	84	,	,	PUNCT
biomedich-691	1	85	ahmad	ahmad	PROPN
biomedich-691	1	86	dahlan	dahlan	PROPN
biomedich-691	1	87	university	university	PROPN
biomedich-691	1	88	,	,	PUNCT
biomedich-691	1	89	yogyakarta	yogyakarta	PROPN
biomedich-691	1	90	,	,	PUNCT
biomedich-691	1	91	indonesia	indonesia	PROPN
biomedich-691	1	92	jl	jl	PROPN
biomedich-691	1	93	.	.	PUNCT
biomedich-691	2	1	universitas	universitas	PROPN
biomedich-691	2	2	ahmad	ahmad	PROPN
biomedich-691	2	3	dahlan	dahlan	PROPN
biomedich-691	2	4	kampus	kampus	PROPN
biomedich-691	2	5	4	4	NUM
biomedich-691	2	6	,	,	PUNCT
biomedich-691	2	7	kragilan	kragilan	ADJ
biomedich-691	2	8	,	,	PUNCT
biomedich-691	2	9	tamanan	tamanan	ADJ
biomedich-691	2	10	,	,	PUNCT
biomedich-691	2	11	kec	kec	PROPN
biomedich-691	2	12	.	.	PUNCT
biomedich-691	2	13	banguntapan	banguntapan	PROPN
biomedich-691	2	14	,	,	PUNCT
biomedich-691	2	15	kabupaten	kabupaten	PROPN
biomedich-691	2	16	bantul	bantul	PROPN
biomedich-691	2	17	,	,	PUNCT
biomedich-691	2	18	daerah	daerah	PROPN
biomedich-691	2	19	istimewa	istimewa	PROPN
biomedich-691	2	20	yogyakarta	yogyakarta	PROPN
biomedich-691	2	21	55191	55191	NUM
biomedich-691	2	22	,	,	PUNCT
biomedich-691	2	23	indonesia	indonesia	PROPN
biomedich-691	2	24	.	.	PUNCT
biomedich-691	3	1	corresponding	correspond	VERB
biomedich-691	3	2	author	author	PROPN
biomedich-691	3	3	*	*	PROPN
biomedich-691	3	4	muhammad2100034023@webmail.uad.ac.id	muhammad2100034023@webmail.uad.ac.id	PROPN
biomedich-691	3	5	manuscript	manuscript	NOUN
biomedich-691	3	6	received	receive	VERB
biomedich-691	3	7	:	:	PUNCT
biomedich-691	3	8	18	18	NUM
biomedich-691	3	9	january	january	PROPN
biomedich-691	3	10	,	,	PUNCT
biomedich-691	3	11	2025	2025	NUM
biomedich-691	3	12	.	.	PUNCT
biomedich-691	4	1	revision	revision	NOUN
biomedich-691	4	2	accepted	accept	VERB
biomedich-691	4	3	:	:	PUNCT
biomedich-691	4	4	15	15	NUM
biomedich-691	4	5	may	may	NOUN
biomedich-691	4	6	,	,	PUNCT
biomedich-691	4	7	2025	2025	NUM
biomedich-691	4	8	.	.	PUNCT
biomedich-691	5	1	published	publish	VERB
biomedich-691	5	2	:	:	PUNCT
biomedich-691	5	3	13	13	NUM
biomedich-691	5	4	june	june	PROPN
biomedich-691	5	5	,	,	PUNCT
biomedich-691	5	6	2025	2025	NUM
biomedich-691	5	7	.	.	PUNCT
biomedich-691	6	1	abstract	abstract	ADJ
biomedich-691	6	2	epidermal	epidermal	ADJ
biomedich-691	6	3	growth	growth	NOUN
biomedich-691	6	4	factor	factor	NOUN
biomedich-691	6	5	receptor	receptor	NOUN
biomedich-691	6	6	(	(	PUNCT
biomedich-691	6	7	egfr	egfr	X
biomedich-691	6	8	)	)	PUNCT
biomedich-691	6	9	is	be	AUX
biomedich-691	6	10	an	an	DET
biomedich-691	6	11	important	important	ADJ
biomedich-691	6	12	target	target	NOUN
biomedich-691	6	13	in	in	ADP
biomedich-691	6	14	breast	breast	NOUN
biomedich-691	6	15	cancer	cancer	NOUN
biomedich-691	6	16	therapy	therapy	NOUN
biomedich-691	6	17	,	,	PUNCT
biomedich-691	6	18	given	give	VERB
biomedich-691	6	19	its	its	PRON
biomedich-691	6	20	role	role	NOUN
biomedich-691	6	21	in	in	ADP
biomedich-691	6	22	tumor	tumor	NOUN
biomedich-691	6	23	cell	cell	NOUN
biomedich-691	6	24	proliferation	proliferation	NOUN
biomedich-691	6	25	,	,	PUNCT
biomedich-691	6	26	motility	motility	NOUN
biomedich-691	6	27	,	,	PUNCT
biomedich-691	6	28	and	and	CCONJ
biomedich-691	6	29	invasion	invasion	NOUN
biomedich-691	6	30	through	through	ADP
biomedich-691	6	31	critical	critical	ADJ
biomedich-691	6	32	signaling	signal	VERB
biomedich-691	6	33	pathways	pathway	NOUN
biomedich-691	6	34	such	such	ADJ
biomedich-691	6	35	as	as	ADP
biomedich-691	6	36	ras	ras	NOUN
biomedich-691	6	37	-	-	NOUN
biomedich-691	6	38	mapk	mapk	NOUN
biomedich-691	6	39	and	and	CCONJ
biomedich-691	6	40	pi3k	pi3k	PROPN
biomedich-691	6	41	/	/	SYM
biomedich-691	6	42	akt	akt	PROPN
biomedich-691	6	43	.	.	PUNCT
biomedich-691	7	1	this	this	DET
biomedich-691	7	2	study	study	NOUN
biomedich-691	7	3	explored	explore	VERB
biomedich-691	7	4	the	the	DET
biomedich-691	7	5	potential	potential	NOUN
biomedich-691	7	6	of	of	ADP
biomedich-691	7	7	artocarpus	artocarpus	PROPN
biomedich-691	7	8	altilis	altilis	PROPN
biomedich-691	7	9	(	(	PUNCT
biomedich-691	7	10	aa	aa	NOUN
biomedich-691	7	11	)	)	PUNCT
biomedich-691	7	12	active	active	ADJ
biomedich-691	7	13	compounds	compound	NOUN
biomedich-691	7	14	,	,	PUNCT
biomedich-691	7	15	which	which	PRON
biomedich-691	7	16	are	be	AUX
biomedich-691	7	17	rich	rich	ADJ
biomedich-691	7	18	in	in	ADP
biomedich-691	7	19	flavonoids	flavonoid	NOUN
biomedich-691	7	20	,	,	PUNCT
biomedich-691	7	21	as	as	ADP
biomedich-691	7	22	an	an	DET
biomedich-691	7	23	alternative	alternative	NOUN
biomedich-691	7	24	to	to	ADP
biomedich-691	7	25	chemotherapy	chemotherapy	NOUN
biomedich-691	7	26	.	.	PUNCT
biomedich-691	8	1	the	the	DET
biomedich-691	8	2	molecular	molecular	ADJ
biomedich-691	8	3	docking	docking	NOUN
biomedich-691	8	4	method	method	NOUN
biomedich-691	8	5	was	be	AUX
biomedich-691	8	6	used	use	VERB
biomedich-691	8	7	to	to	PART
biomedich-691	8	8	predict	predict	VERB
biomedich-691	8	9	the	the	DET
biomedich-691	8	10	interaction	interaction	NOUN
biomedich-691	8	11	between	between	ADP
biomedich-691	8	12	aa	aa	PROPN
biomedich-691	8	13	compounds	compound	NOUN
biomedich-691	8	14	and	and	CCONJ
biomedich-691	8	15	egfr	egfr	ADJ
biomedich-691	8	16	protein	protein	NOUN
biomedich-691	8	17	(	(	PUNCT
biomedich-691	8	18	pdb	pdb	PROPN
biomedich-691	8	19	i	i	PROPN
biomedich-691	8	20	d	d	PROPN
biomedich-691	8	21	:	:	PUNCT
biomedich-691	8	22	2j6	2j6	NUM
biomedich-691	8	23	m	m	NOUN
biomedich-691	8	24	)	)	PUNCT
biomedich-691	8	25	.	.	PUNCT
biomedich-691	9	1	docking	dock	VERB
biomedich-691	9	2	validation	validation	NOUN
biomedich-691	9	3	showed	show	VERB
biomedich-691	9	4	an	an	DET
biomedich-691	9	5	rmsd	rmsd	ADJ
biomedich-691	9	6	value	value	NOUN
biomedich-691	9	7	of	of	ADP
biomedich-691	9	8	0.854	0.854	NUM
biomedich-691	9	9	å	å	NOUN
biomedich-691	9	10	,	,	PUNCT
biomedich-691	9	11	indicating	indicate	VERB
biomedich-691	9	12	high	high	ADJ
biomedich-691	9	13	accuracy	accuracy	NOUN
biomedich-691	9	14	.	.	PUNCT
biomedich-691	10	1	ellagic	ellagic	ADJ
biomedich-691	10	2	acid	acid	PROPN
biomedich-691	10	3	showed	show	VERB
biomedich-691	10	4	the	the	DET
biomedich-691	10	5	best	good	ADJ
biomedich-691	10	6	binding	bind	VERB
biomedich-691	10	7	affinity	affinity	NOUN
biomedich-691	10	8	(	(	PUNCT
biomedich-691	10	9	-8.4	-8.4	X
biomedich-691	10	10	kcal	kcal	NOUN
biomedich-691	10	11	/	/	SYM
biomedich-691	10	12	mol	mol	NOUN
biomedich-691	10	13	)	)	PUNCT
biomedich-691	10	14	,	,	PUNCT
biomedich-691	10	15	followed	follow	VERB
biomedich-691	10	16	by	by	ADP
biomedich-691	10	17	quercetin	quercetin	NOUN
biomedich-691	10	18	(	(	PUNCT
biomedich-691	10	19	7.3	7.3	NUM
biomedich-691	10	20	kcal	kcal	NOUN
biomedich-691	10	21	/	/	SYM
biomedich-691	10	22	mol	mol	NOUN
biomedich-691	10	23	)	)	PUNCT
biomedich-691	10	24	,	,	PUNCT
biomedich-691	10	25	catechin	catechin	NOUN
biomedich-691	10	26	,	,	PUNCT
biomedich-691	10	27	and	and	CCONJ
biomedich-691	10	28	epicatechin	epicatechin	PROPN
biomedich-691	10	29	(	(	PUNCT
biomedich-691	10	30	-7.2	-7.2	PROPN
biomedich-691	10	31	kcal	kcal	PROPN
biomedich-691	10	32	/	/	SYM
biomedich-691	10	33	mol	mol	NOUN
biomedich-691	10	34	)	)	PUNCT
biomedich-691	10	35	.	.	PUNCT
biomedich-691	11	1	residue	residue	NOUN
biomedich-691	11	2	analysis	analysis	NOUN
biomedich-691	11	3	revealed	reveal	VERB
biomedich-691	11	4	that	that	SCONJ
biomedich-691	11	5	met793	met793	NOUN
biomedich-691	11	6	plays	play	VERB
biomedich-691	11	7	a	a	DET
biomedich-691	11	8	key	key	ADJ
biomedich-691	11	9	role	role	NOUN
biomedich-691	11	10	in	in	ADP
biomedich-691	11	11	the	the	DET
biomedich-691	11	12	stability	stability	NOUN
biomedich-691	11	13	of	of	ADP
biomedich-691	11	14	the	the	DET
biomedich-691	11	15	interaction	interaction	NOUN
biomedich-691	11	16	.	.	PUNCT
biomedich-691	12	1	interaction	interaction	NOUN
biomedich-691	12	2	visualization	visualization	NOUN
biomedich-691	12	3	and	and	CCONJ
biomedich-691	12	4	admet	admet	NOUN
biomedich-691	12	5	prediction	prediction	NOUN
biomedich-691	12	6	showed	show	VERB
biomedich-691	12	7	that	that	SCONJ
biomedich-691	12	8	most	most	ADJ
biomedich-691	12	9	of	of	ADP
biomedich-691	12	10	the	the	DET
biomedich-691	12	11	compounds	compound	NOUN
biomedich-691	12	12	fulfilled	fulfil	VERB
biomedich-691	12	13	lipinski	lipinski	PROPN
biomedich-691	12	14	's	's	PART
biomedich-691	12	15	rule	rule	NOUN
biomedich-691	12	16	of	of	ADP
biomedich-691	12	17	five	five	NUM
biomedich-691	12	18	,	,	PUNCT
biomedich-691	12	19	with	with	ADP
biomedich-691	12	20	no	no	DET
biomedich-691	12	21	risk	risk	NOUN
biomedich-691	12	22	of	of	ADP
biomedich-691	12	23	hepatotoxicity	hepatotoxicity	NOUN
biomedich-691	12	24	or	or	CCONJ
biomedich-691	12	25	mutagenesis	mutagenesis	NOUN
biomedich-691	12	26	.	.	PUNCT
biomedich-691	13	1	potential	potential	ADJ
biomedich-691	13	2	compounds	compound	NOUN
biomedich-691	13	3	such	such	ADJ
biomedich-691	13	4	as	as	ADP
biomedich-691	13	5	quercetin	quercetin	NOUN
biomedich-691	13	6	and	and	CCONJ
biomedich-691	13	7	epicatechin	epicatechin	NOUN
biomedich-691	13	8	showed	show	VERB
biomedich-691	13	9	comparable	comparable	ADJ
biomedich-691	13	10	performance	performance	NOUN
biomedich-691	13	11	to	to	ADP
biomedich-691	13	12	doxorubicin	doxorubicin	PROPN
biomedich-691	13	13	,	,	PUNCT
biomedich-691	13	14	but	but	CCONJ
biomedich-691	13	15	with	with	ADP
biomedich-691	13	16	lower	low	ADJ
biomedich-691	13	17	potential	potential	ADJ
biomedich-691	13	18	side	side	NOUN
biomedich-691	13	19	effects	effect	NOUN
biomedich-691	13	20	.	.	PUNCT
biomedich-691	14	1	these	these	DET
biomedich-691	14	2	results	result	NOUN
biomedich-691	14	3	strengthen	strengthen	VERB
biomedich-691	14	4	the	the	DET
biomedich-691	14	5	role	role	NOUN
biomedich-691	14	6	of	of	ADP
biomedich-691	14	7	natural	natural	ADJ
biomedich-691	14	8	compounds	compound	NOUN
biomedich-691	14	9	as	as	ADP
biomedich-691	14	10	candidates	candidate	NOUN
biomedich-691	14	11	for	for	ADP
biomedich-691	14	12	egfr	egfr	ADV
biomedich-691	14	13	-	-	PUNCT
biomedich-691	14	14	targeted	target	VERB
biomedich-691	14	15	cancer	cancer	NOUN
biomedich-691	14	16	therapy	therapy	NOUN
biomedich-691	14	17	,	,	PUNCT
biomedich-691	14	18	providing	provide	VERB
biomedich-691	14	19	a	a	DET
biomedich-691	14	20	basis	basis	NOUN
biomedich-691	14	21	for	for	ADP
biomedich-691	14	22	the	the	DET
biomedich-691	14	23	development	development	NOUN
biomedich-691	14	24	of	of	ADP
biomedich-691	14	25	safer	safe	ADJ
biomedich-691	14	26	and	and	CCONJ
biomedich-691	14	27	more	more	ADV
biomedich-691	14	28	effective	effective	ADJ
biomedich-691	14	29	anticancer	anticancer	NOUN
biomedich-691	14	30	drugs	drug	NOUN
biomedich-691	14	31	.	.	PUNCT
biomedich-691	15	1	keywords	keyword	NOUN
biomedich-691	15	2	:	:	PUNCT
biomedich-691	15	3	breast	breast	NOUN
biomedich-691	15	4	cancer	cancer	NOUN
biomedich-691	15	5	;	;	PUNCT
biomedich-691	15	6	egfr	egfr	X
biomedich-691	15	7	;	;	PUNCT
biomedich-691	15	8	artocarpus	artocarpus	PROPN
biomedich-691	15	9	altilis	altilis	PROPN
biomedich-691	15	10	;	;	PUNCT
biomedich-691	15	11	molecular	molecular	ADJ
biomedich-691	15	12	docking	docking	NOUN
biomedich-691	15	13	.	.	PUNCT
biomedich-691	16	1	introduction	introduction	NOUN
biomedich-691	16	2	breast	breast	NOUN
biomedich-691	16	3	cancer	cancer	NOUN
biomedich-691	16	4	is	be	AUX
biomedich-691	16	5	a	a	DET
biomedich-691	16	6	global	global	ADJ
biomedich-691	16	7	problem	problem	NOUN
biomedich-691	16	8	to	to	ADP
biomedich-691	16	9	this	this	DET
biomedich-691	16	10	day	day	NOUN
biomedich-691	16	11	,	,	PUNCT
biomedich-691	16	12	data	datum	NOUN
biomedich-691	16	13	shows	show	VERB
biomedich-691	16	14	that	that	SCONJ
biomedich-691	16	15	this	this	DET
biomedich-691	16	16	disease	disease	NOUN
biomedich-691	16	17	was	be	AUX
biomedich-691	16	18	experienced	experience	VERB
biomedich-691	16	19	by	by	ADP
biomedich-691	16	20	11.7	11.7	NUM
biomedich-691	16	21	%	%	NOUN
biomedich-691	16	22	of	of	ADP
biomedich-691	16	23	the	the	DET
biomedich-691	16	24	world	world	NOUN
biomedich-691	16	25	's	's	PART
biomedich-691	16	26	population	population	NOUN
biomedich-691	16	27	in	in	ADP
biomedich-691	16	28	2020	2020	NUM
biomedich-691	16	29	.	.	PUNCT
biomedich-691	17	1	(	(	PUNCT
biomedich-691	17	2	sung	sing	VERB
biomedich-691	17	3	et	et	PROPN
biomedich-691	17	4	al	al	PROPN
biomedich-691	17	5	.	.	PROPN
biomedich-691	17	6	,	,	PUNCT
biomedich-691	17	7	2021)the	2021)the	DET
biomedich-691	17	8	development	development	NOUN
biomedich-691	17	9	of	of	ADP
biomedich-691	17	10	breast	breast	NOUN
biomedich-691	17	11	cancer	cancer	NOUN
biomedich-691	17	12	through	through	ADP
biomedich-691	17	13	several	several	ADJ
biomedich-691	17	14	pathways	pathway	NOUN
biomedich-691	17	15	,	,	PUNCT
biomedich-691	17	16	one	one	NUM
biomedich-691	17	17	of	of	ADP
biomedich-691	17	18	which	which	PRON
biomedich-691	17	19	is	be	AUX
biomedich-691	17	20	the	the	DET
biomedich-691	17	21	epidermal	epidermal	ADJ
biomedich-691	17	22	growth	growth	NOUN
biomedich-691	17	23	factor	factor	NOUN
biomedich-691	17	24	receptor	receptor	NOUN
biomedich-691	17	25	(	(	PUNCT
biomedich-691	17	26	egfr	egfr	X
biomedich-691	17	27	)	)	PUNCT
biomedich-691	17	28	which	which	PRON
biomedich-691	17	29	is	be	AUX
biomedich-691	17	30	stimulated	stimulate	VERB
biomedich-691	17	31	by	by	ADP
biomedich-691	17	32	epidermal	epidermal	ADJ
biomedich-691	17	33	growth	growth	NOUN
biomedich-691	17	34	factor	factor	NOUN
biomedich-691	17	35	(	(	PUNCT
biomedich-691	17	36	wilson	wilson	PROPN
biomedich-691	17	37	et	et	PROPN
biomedich-691	17	38	al	al	PROPN
biomedich-691	17	39	.	.	PROPN
biomedich-691	17	40	,	,	PUNCT
biomedich-691	17	41	2009	2009	NUM
biomedich-691	17	42	)	)	PUNCT
biomedich-691	17	43	.	.	PUNCT
biomedich-691	18	1	treatment	treatment	NOUN
biomedich-691	18	2	for	for	ADP
biomedich-691	18	3	breast	breast	NOUN
biomedich-691	18	4	cancer	cancer	NOUN
biomedich-691	18	5	involves	involve	VERB
biomedich-691	18	6	multidisciplinary	multidisciplinary	ADJ
biomedich-691	18	7	science	science	NOUN
biomedich-691	18	8	including	include	VERB
biomedich-691	18	9	surgery	surgery	NOUN
biomedich-691	18	10	,	,	PUNCT
biomedich-691	18	11	radiotherapy	radiotherapy	NOUN
biomedich-691	18	12	,	,	PUNCT
biomedich-691	18	13	neoadjuvant	neoadjuvant	ADJ
biomedich-691	18	14	and	and	CCONJ
biomedich-691	18	15	adjuvant	adjuvant	ADJ
biomedich-691	18	16	(	(	PUNCT
biomedich-691	18	17	di	di	NOUN
biomedich-691	18	18	nardo	nardo	PROPN
biomedich-691	18	19	et	et	PROPN
biomedich-691	18	20	al	al	PROPN
biomedich-691	18	21	.	.	PROPN
biomedich-691	18	22	,	,	PUNCT
biomedich-691	18	23	2022	2022	NUM
biomedich-691	18	24	)	)	PUNCT
biomedich-691	18	25	.	.	PUNCT
biomedich-691	19	1	treatment	treatment	NOUN
biomedich-691	19	2	with	with	ADP
biomedich-691	19	3	chemotherapy	chemotherapy	NOUN
biomedich-691	19	4	is	be	AUX
biomedich-691	19	5	the	the	DET
biomedich-691	19	6	main	main	ADJ
biomedich-691	19	7	choice	choice	NOUN
biomedich-691	19	8	that	that	PRON
biomedich-691	19	9	is	be	AUX
biomedich-691	19	10	still	still	ADV
biomedich-691	19	11	often	often	ADV
biomedich-691	19	12	used	use	VERB
biomedich-691	19	13	today	today	NOUN
biomedich-691	19	14	.	.	PUNCT
biomedich-691	20	1	however	however	ADV
biomedich-691	20	2	,	,	PUNCT
biomedich-691	20	3	the	the	DET
biomedich-691	20	4	long	long	ADJ
biomedich-691	20	5	-	-	PUNCT
biomedich-691	20	6	term	term	NOUN
biomedich-691	20	7	side	side	NOUN
biomedich-691	20	8	effects	effect	NOUN
biomedich-691	20	9	that	that	PRON
biomedich-691	20	10	arise	arise	VERB
biomedich-691	20	11	can	can	AUX
biomedich-691	20	12	include	include	VERB
biomedich-691	20	13	fatigue	fatigue	NOUN
biomedich-691	20	14	,	,	PUNCT
biomedich-691	20	15	insomnia	insomnia	NOUN
biomedich-691	20	16	,	,	PUNCT
biomedich-691	20	17	peripheral	peripheral	ADJ
biomedich-691	20	18	neuropathy	neuropathy	ADJ
biomedich-691	20	19	,	,	PUNCT
biomedich-691	20	20	cognitive	cognitive	ADJ
biomedich-691	20	21	impairment	impairment	NOUN
biomedich-691	20	22	,	,	PUNCT
biomedich-691	20	23	cardiotoxicity	cardiotoxicity	NOUN
biomedich-691	20	24	to	to	ADP
biomedich-691	20	25	triggering	trigger	VERB
biomedich-691	20	26	the	the	DET
biomedich-691	20	27	emergence	emergence	NOUN
biomedich-691	20	28	of	of	ADP
biomedich-691	20	29	other	other	ADJ
biomedich-691	20	30	malignancies	malignancy	NOUN
biomedich-691	20	31	(	(	PUNCT
biomedich-691	20	32	goedendorp	goedendorp	PROPN
biomedich-691	20	33	et	et	PROPN
biomedich-691	20	34	al	al	PROPN
biomedich-691	20	35	.	.	PROPN
biomedich-691	20	36	,	,	PUNCT
biomedich-691	20	37	2012	2012	NUM
biomedich-691	20	38	;	;	PUNCT
biomedich-691	20	39	zamorano	zamorano	PROPN
biomedich-691	20	40	et	et	PROPN
biomedich-691	20	41	al	al	PROPN
biomedich-691	20	42	.	.	PROPN
biomedich-691	20	43	,	,	PUNCT
biomedich-691	20	44	2016	2016	NUM
biomedich-691	20	45	)	)	PUNCT
biomedich-691	20	46	.	.	PUNCT
biomedich-691	21	1	breadfruit	breadfruit	PROPN
biomedich-691	21	2	(	(	PUNCT
biomedich-691	21	3	arthocarpus	arthocarpus	PROPN
biomedich-691	21	4	altilis	altilis	PROPN
biomedich-691	21	5	)	)	PUNCT
biomedich-691	21	6	belongs	belong	VERB
biomedich-691	21	7	to	to	ADP
biomedich-691	21	8	the	the	DET
biomedich-691	21	9	moraceae	moraceae	PROPN
biomedich-691	21	10	family	family	NOUN
biomedich-691	21	11	which	which	PRON
biomedich-691	21	12	is	be	AUX
biomedich-691	21	13	widely	widely	ADV
biomedich-691	21	14	used	use	VERB
biomedich-691	21	15	by	by	ADP
biomedich-691	21	16	the	the	DET
biomedich-691	21	17	community	community	NOUN
biomedich-691	21	18	as	as	ADP
biomedich-691	21	19	a	a	DET
biomedich-691	21	20	traditional	traditional	ADJ
biomedich-691	21	21	medicine	medicine	NOUN
biomedich-691	21	22	(	(	PUNCT
biomedich-691	21	23	ganeson	ganeson	NOUN
biomedich-691	21	24	et	et	PROPN
biomedich-691	21	25	al	al	PROPN
biomedich-691	21	26	.	.	PROPN
biomedich-691	21	27	,	,	PUNCT
biomedich-691	21	28	2018	2018	NUM
biomedich-691	21	29	)	)	PUNCT
biomedich-691	21	30	.	.	PUNCT
biomedich-691	22	1	the	the	DET
biomedich-691	22	2	largest	large	ADJ
biomedich-691	22	3	content	content	NOUN
biomedich-691	22	4	of	of	ADP
biomedich-691	22	5	aa	aa	PROPN
biomedich-691	22	6	is	be	AUX
biomedich-691	22	7	flavonoids	flavonoid	NOUN
biomedich-691	22	8	,	,	PUNCT
biomedich-691	22	9	flavonoids	flavonoid	NOUN
biomedich-691	22	10	have	have	VERB
biomedich-691	22	11	strong	strong	ADJ
biomedich-691	22	12	anticancer	anticancer	NOUN
biomedich-691	22	13	properties	property	NOUN
biomedich-691	22	14	that	that	PRON
biomedich-691	22	15	function	function	VERB
biomedich-691	22	16	as	as	ADP
biomedich-691	22	17	antioxidants	antioxidant	NOUN
biomedich-691	22	18	in	in	ADP
biomedich-691	22	19	normal	normal	ADJ
biomedich-691	22	20	cells	cell	NOUN
biomedich-691	22	21	and	and	CCONJ
biomedich-691	22	22	as	as	SCONJ
biomedich-691	22	23	pro	pro	ADJ
biomedich-691	22	24	-	-	NOUN
biomedich-691	22	25	oxidants	oxidant	NOUN
biomedich-691	22	26	in	in	ADP
biomedich-691	22	27	cancer	cancer	NOUN
biomedich-691	22	28	cells	cell	NOUN
biomedich-691	22	29	that	that	PRON
biomedich-691	22	30	trigger	trigger	NOUN
biomedich-691	22	31	oxidative	oxidative	ADJ
biomedich-691	22	32	stress	stress	NOUN
biomedich-691	22	33	and	and	CCONJ
biomedich-691	22	34	induce	induce	VERB
biomedich-691	22	35	apoptosis	apoptosis	NOUN
biomedich-691	22	36	,	,	PUNCT
biomedich-691	22	37	mainly	mainly	ADV
biomedich-691	22	38	due	due	ADP
biomedich-691	22	39	to	to	ADP
biomedich-691	22	40	the	the	DET
biomedich-691	22	41	content	content	NOUN
biomedich-691	22	42	of	of	ADP
biomedich-691	22	43	artocarpin	artocarpin	NOUN
biomedich-691	22	44	(	(	PUNCT
biomedich-691	22	45	jantapaso	jantapaso	PROPN
biomedich-691	22	46	&	&	CCONJ
biomedich-691	22	47	mittraparparthorn	mittraparparthorn	ADJ
biomedich-691	22	48	,	,	PUNCT
biomedich-691	22	49	2022	2022	NUM
biomedich-691	22	50	)	)	PUNCT
biomedich-691	22	51	.	.	PUNCT
biomedich-691	23	1	flavonoids	flavonoid	NOUN
biomedich-691	23	2	show	show	VERB
biomedich-691	23	3	anti	anti	ADJ
biomedich-691	23	4	-	-	ADJ
biomedich-691	23	5	metastatic	metastatic	ADJ
biomedich-691	23	6	effects	effect	NOUN
biomedich-691	23	7	by	by	ADP
biomedich-691	23	8	inhibiting	inhibit	VERB
biomedich-691	23	9	migration	migration	NOUN
biomedich-691	23	10	,	,	PUNCT
biomedich-691	23	11	invasion	invasion	NOUN
biomedich-691	23	12	of	of	ADP
biomedich-691	23	13	cancer	cancer	NOUN
biomedich-691	23	14	cells	cell	NOUN
biomedich-691	23	15	,	,	PUNCT
biomedich-691	23	16	and	and	CCONJ
biomedich-691	23	17	angiogenesis	angiogenesis	NOUN
biomedich-691	23	18	through	through	ADP
biomedich-691	23	19	modulation	modulation	NOUN
biomedich-691	23	20	of	of	ADP
biomedich-691	23	21	important	important	ADJ
biomedich-691	23	22	signaling	signal	VERB
biomedich-691	23	23	pathways	pathway	NOUN
biomedich-691	23	24	such	such	ADJ
biomedich-691	23	25	as	as	ADP
biomedich-691	23	26	nf	nf	NOUN
biomedich-691	23	27	-	-	PUNCT
biomedich-691	23	28	κb	κb	NOUN
biomedich-691	23	29	,	,	PUNCT
biomedich-691	23	30	ap-1	ap-1	ADV
biomedich-691	23	31	,	,	PUNCT
biomedich-691	23	32	p53	p53	NOUN
biomedich-691	23	33	,	,	PUNCT
biomedich-691	23	34	and	and	CCONJ
biomedich-691	23	35	pi3k	pi3k	PROPN
biomedich-691	23	36	/	/	SYM
biomedich-691	23	37	akt	akt	PROPN
biomedich-691	23	38	(	(	PUNCT
biomedich-691	23	39	aswathy	aswathy	ADJ
biomedich-691	23	40	et	et	PROPN
biomedich-691	23	41	al	al	PROPN
biomedich-691	23	42	.	.	PROPN
biomedich-691	23	43	,	,	PUNCT
biomedich-691	23	44	2024	2024	NUM
biomedich-691	23	45	)	)	PUNCT
biomedich-691	23	46	.	.	PUNCT
biomedich-691	24	1	flavonoids	flavonoid	NOUN
biomedich-691	24	2	in	in	ADP
biomedich-691	24	3	aa	aa	NOUN
biomedich-691	24	4	can	can	AUX
biomedich-691	24	5	affect	affect	VERB
biomedich-691	24	6	epigenetic	epigenetic	ADJ
biomedich-691	24	7	mechanisms	mechanism	NOUN
biomedich-691	24	8	,	,	PUNCT
biomedich-691	24	9	such	such	ADJ
biomedich-691	24	10	as	as	ADP
biomedich-691	24	11	dna	dna	PROPN
biomedich-691	24	12	methylation	methylation	NOUN
biomedich-691	24	13	and	and	CCONJ
biomedich-691	24	14	histone	histone	NOUN
biomedich-691	24	15	modifications	modification	NOUN
biomedich-691	24	16	,	,	PUNCT
biomedich-691	24	17	making	make	VERB
biomedich-691	24	18	them	they	PRON
biomedich-691	24	19	important	important	ADJ
biomedich-691	24	20	candidates	candidate	NOUN
biomedich-691	24	21	for	for	ADP
biomedich-691	24	22	cancer	cancer	NOUN
biomedich-691	24	23	prevention	prevention	NOUN
biomedich-691	24	24	and	and	CCONJ
biomedich-691	24	25	therapy	therapy	NOUN
biomedich-691	24	26	(	(	PUNCT
biomedich-691	24	27	sitarek	sitarek	NOUN
biomedich-691	24	28	et	et	PROPN
biomedich-691	24	29	al	al	PROPN
biomedich-691	24	30	.	.	PROPN
biomedich-691	24	31	,	,	PUNCT
biomedich-691	24	32	2024	2024	NUM
biomedich-691	24	33	)	)	PUNCT
biomedich-691	24	34	.	.	PUNCT
biomedich-691	25	1	molecular	molecular	ADJ
biomedich-691	25	2	docking	docking	NOUN
biomedich-691	25	3	is	be	AUX
biomedich-691	25	4	a	a	DET
biomedich-691	25	5	method	method	NOUN
biomedich-691	25	6	to	to	PART
biomedich-691	25	7	predict	predict	VERB
biomedich-691	25	8	how	how	SCONJ
biomedich-691	25	9	ligands	ligand	NOUN
biomedich-691	25	10	interact	interact	VERB
biomedich-691	25	11	with	with	ADP
biomedich-691	25	12	receptor	receptor	NOUN
biomedich-691	25	13	proteins	protein	NOUN
biomedich-691	25	14	,	,	PUNCT
biomedich-691	25	15	as	as	ADV
biomedich-691	25	16	well	well	ADV
biomedich-691	25	17	as	as	ADP
biomedich-691	25	18	assess	assess	VERB
biomedich-691	25	19	their	their	PRON
biomedich-691	25	20	binding	bind	VERB
biomedich-691	25	21	affinity	affinity	NOUN
biomedich-691	25	22	and	and	CCONJ
biomedich-691	25	23	determine	determine	VERB
biomedich-691	25	24	the	the	DET
biomedich-691	25	25	optimal	optimal	ADJ
biomedich-691	25	26	conformation	conformation	NOUN
biomedich-691	25	27	and	and	CCONJ
biomedich-691	25	28	orientation	orientation	NOUN
biomedich-691	25	29	of	of	ADP
biomedich-691	25	30	the	the	DET
biomedich-691	25	31	ligand	ligand	NOUN
biomedich-691	25	32	when	when	SCONJ
biomedich-691	25	33	interacting	interact	VERB
biomedich-691	25	34	with	with	ADP
biomedich-691	25	35	the	the	DET
biomedich-691	25	36	target	target	NOUN
biomedich-691	25	37	protein	protein	NOUN
biomedich-691	25	38	(	(	PUNCT
biomedich-691	25	39	meng	meng	PROPN
biomedich-691	25	40	et	et	PROPN
biomedich-691	25	41	al	al	PROPN
biomedich-691	25	42	.	.	PROPN
biomedich-691	25	43	,	,	PUNCT
biomedich-691	25	44	2011	2011	NUM
biomedich-691	25	45	)	)	PUNCT
biomedich-691	25	46	.	.	PUNCT
biomedich-691	26	1	molecular	molecular	ADJ
biomedich-691	26	2	docking	docking	NOUN
biomedich-691	26	3	works	work	VERB
biomedich-691	26	4	at	at	ADP
biomedich-691	26	5	the	the	DET
biomedich-691	26	6	atomic	atomic	ADJ
biomedich-691	26	7	level	level	NOUN
biomedich-691	26	8	to	to	PART
biomedich-691	26	9	understand	understand	VERB
biomedich-691	26	10	the	the	DET
biomedich-691	26	11	interaction	interaction	NOUN
biomedich-691	26	12	process	process	NOUN
biomedich-691	26	13	of	of	ADP
biomedich-691	26	14	small	small	ADJ
biomedich-691	26	15	molecules	molecule	NOUN
biomedich-691	26	16	at	at	ADP
biomedich-691	26	17	the	the	DET
biomedich-691	26	18	target	target	NOUN
biomedich-691	26	19	protein	protein	NOUN
biomedich-691	26	20	binding	bind	VERB
biomedich-691	26	21	site	site	NOUN
biomedich-691	26	22	.	.	PUNCT
biomedich-691	27	1	(	(	PUNCT
biomedich-691	27	2	agu	agu	NOUN
biomedich-691	27	3	et	et	PROPN
biomedich-691	27	4	al	al	PROPN
biomedich-691	27	5	.	.	PROPN
biomedich-691	27	6	,	,	PUNCT
biomedich-691	27	7	2023	2023	NUM
biomedich-691	27	8	)	)	PUNCT
biomedich-691	27	9	.	.	PUNCT
biomedich-691	28	1	the	the	DET
biomedich-691	28	2	docking	docking	NOUN
biomedich-691	28	3	process	process	NOUN
biomedich-691	28	4	often	often	ADV
biomedich-691	28	5	uses	use	VERB
biomedich-691	28	6	molecular	molecular	ADJ
biomedich-691	28	7	mechanics	mechanic	NOUN
biomedich-691	28	8	to	to	PART
biomedich-691	28	9	quickly	quickly	ADV
biomedich-691	28	10	evaluate	evaluate	VERB
biomedich-691	28	11	ligand	ligand	NOUN
biomedich-691	28	12	conformation	conformation	NOUN
biomedich-691	28	13	,	,	PUNCT
biomedich-691	28	14	match	match	VERB
biomedich-691	28	15	the	the	DET
biomedich-691	28	16	3d	3d	NUM
biomedich-691	28	17	shape	shape	NOUN
biomedich-691	28	18	of	of	ADP
biomedich-691	28	19	the	the	DET
biomedich-691	28	20	ligand	ligand	NOUN
biomedich-691	28	21	with	with	ADP
biomedich-691	28	22	the	the	DET
biomedich-691	28	23	target	target	NOUN
biomedich-691	28	24	,	,	PUNCT
biomedich-691	28	25	or	or	CCONJ
biomedich-691	28	26	use	use	VERB
biomedich-691	28	27	hybrid	hybrid	ADJ
biomedich-691	28	28	methods	method	NOUN
biomedich-691	28	29	to	to	PART
biomedich-691	28	30	obtain	obtain	VERB
biomedich-691	28	31	more	more	ADV
biomedich-691	28	32	accurate	accurate	ADJ
biomedich-691	28	33	predictions	prediction	NOUN
biomedich-691	28	34	(	(	PUNCT
biomedich-691	28	35	soleymani	soleymani	PROPN
biomedich-691	28	36	et	et	PROPN
biomedich-691	28	37	al	al	PROPN
biomedich-691	28	38	.	.	PROPN
biomedich-691	28	39	,	,	PUNCT
biomedich-691	28	40	2022	2022	NUM
biomedich-691	28	41	)	)	PUNCT
biomedich-691	28	42	.	.	PUNCT
biomedich-691	29	1	this	this	DET
biomedich-691	29	2	study	study	NOUN
biomedich-691	29	3	aims	aim	VERB
biomedich-691	29	4	to	to	PART
biomedich-691	29	5	predict	predict	VERB
biomedich-691	29	6	the	the	DET
biomedich-691	29	7	potential	potential	NOUN
biomedich-691	29	8	of	of	ADP
biomedich-691	29	9	aa	aa	NOUN
biomedich-691	29	10	as	as	ADP
biomedich-691	29	11	an	an	DET
biomedich-691	29	12	anti	anti	ADJ
biomedich-691	29	13	-	-	ADJ
biomedich-691	29	14	breast	breast	ADJ
biomedich-691	29	15	cancer	cancer	NOUN
biomedich-691	29	16	through	through	ADP
biomedich-691	29	17	the	the	DET
biomedich-691	29	18	egfr	egfr	ADJ
biomedich-691	29	19	receptor	receptor	NOUN
biomedich-691	29	20	through	through	ADP
biomedich-691	29	21	molecular	molecular	ADJ
biomedich-691	29	22	docking	docking	NOUN
biomedich-691	29	23	studies	study	NOUN
biomedich-691	29	24	.	.	PUNCT
biomedich-691	30	1	https://doi.org/10.14421/biomedich.2025.141.199-204	https://doi.org/10.14421/biomedich.2025.141.199-204	PRON
biomedich-691	30	2	mailto:muhammad2100034023@webmail.uad.ac.id	mailto:muhammad2100034023@webmail.uad.ac.id	NOUN
biomedich-691	31	1	200	200	NUM
biomedich-691	31	2	biology	biology	NOUN
biomedich-691	31	3	,	,	PUNCT
biomedich-691	31	4	medicine	medicine	NOUN
biomedich-691	31	5	,	,	PUNCT
biomedich-691	31	6	&	&	CCONJ
biomedich-691	31	7	natural	natural	ADJ
biomedich-691	31	8	product	product	NOUN
biomedich-691	31	9	chemistry	chemistry	NOUN
biomedich-691	31	10	14	14	NUM
biomedich-691	31	11	(	(	PUNCT
biomedich-691	31	12	1	1	NUM
biomedich-691	31	13	)	)	PUNCT
biomedich-691	31	14	,	,	PUNCT
biomedich-691	31	15	2025	2025	NUM
biomedich-691	31	16	:	:	PUNCT
biomedich-691	31	17	199	199	NUM
biomedich-691	31	18	-	-	SYM
biomedich-691	31	19	204	204	NUM
biomedich-691	31	20	materials	material	NOUN
biomedich-691	31	21	and	and	CCONJ
biomedich-691	31	22	methods	method	NOUN
biomedich-691	31	23	preparation	preparation	NOUN
biomedich-691	31	24	of	of	ADP
biomedich-691	31	25	test	test	NOUN
biomedich-691	31	26	receptors	receptor	NOUN
biomedich-691	31	27	and	and	CCONJ
biomedich-691	31	28	ligands	ligand	NOUN
biomedich-691	31	29	this	this	DET
biomedich-691	31	30	study	study	NOUN
biomedich-691	31	31	used	use	VERB
biomedich-691	31	32	the	the	DET
biomedich-691	31	33	egfr	egfr	ADJ
biomedich-691	31	34	protein	protein	NOUN
biomedich-691	31	35	with	with	ADP
biomedich-691	31	36	pdb	pdb	PROPN
biomedich-691	31	37	i	i	PROPN
biomedich-691	31	38	d	d	PROPN
biomedich-691	31	39	:	:	PUNCT
biomedich-691	31	40	2j6	2j6	NUM
biomedich-691	31	41	m	m	AUX
biomedich-691	31	42	obtained	obtain	VERB
biomedich-691	31	43	through	through	ADP
biomedich-691	31	44	https://www.rcsb.org/.	https://www.rcsb.org/.	VERB
biomedich-691	31	45	this	this	DET
biomedich-691	31	46	protein	protein	NOUN
biomedich-691	31	47	has	have	AUX
biomedich-691	31	48	been	be	AUX
biomedich-691	31	49	used	use	VERB
biomedich-691	31	50	previously	previously	ADV
biomedich-691	31	51	in	in	ADP
biomedich-691	31	52	studies	study	NOUN
biomedich-691	31	53	that	that	PRON
biomedich-691	31	54	have	have	VERB
biomedich-691	31	55	the	the	DET
biomedich-691	31	56	potential	potential	NOUN
biomedich-691	31	57	for	for	ADP
biomedich-691	31	58	interaction	interaction	NOUN
biomedich-691	31	59	with	with	ADP
biomedich-691	31	60	breast	breast	NOUN
biomedich-691	31	61	cancer	cancer	NOUN
biomedich-691	31	62	(	(	PUNCT
biomedich-691	31	63	acharya	acharya	PROPN
biomedich-691	31	64	et	et	PROPN
biomedich-691	31	65	al	al	PROPN
biomedich-691	31	66	.	.	PROPN
biomedich-691	31	67	,	,	PUNCT
biomedich-691	31	68	2019	2019	NUM
biomedich-691	31	69	)	)	PUNCT
biomedich-691	31	70	.	.	PUNCT
biomedich-691	32	1	the	the	DET
biomedich-691	32	2	protein	protein	NOUN
biomedich-691	32	3	repair	repair	NOUN
biomedich-691	32	4	process	process	NOUN
biomedich-691	32	5	is	be	AUX
biomedich-691	32	6	carried	carry	VERB
biomedich-691	32	7	out	out	ADP
biomedich-691	32	8	to	to	PART
biomedich-691	32	9	separate	separate	VERB
biomedich-691	32	10	the	the	DET
biomedich-691	32	11	protein	protein	NOUN
biomedich-691	32	12	chain	chain	NOUN
biomedich-691	32	13	from	from	ADP
biomedich-691	32	14	other	other	ADJ
biomedich-691	32	15	molecules	molecule	NOUN
biomedich-691	32	16	such	such	ADJ
biomedich-691	32	17	as	as	ADP
biomedich-691	32	18	natural	natural	ADJ
biomedich-691	32	19	ligands	ligand	NOUN
biomedich-691	32	20	,	,	PUNCT
biomedich-691	32	21	water	water	NOUN
biomedich-691	32	22	,	,	PUNCT
biomedich-691	32	23	and	and	CCONJ
biomedich-691	32	24	cofactors	cofactor	NOUN
biomedich-691	32	25	(	(	PUNCT
biomedich-691	32	26	syahputra	syahputra	PROPN
biomedich-691	32	27	et	et	PROPN
biomedich-691	32	28	al	al	PROPN
biomedich-691	32	29	.	.	PROPN
biomedich-691	32	30	,	,	PUNCT
biomedich-691	32	31	2022	2022	NUM
biomedich-691	32	32	)	)	PUNCT
biomedich-691	32	33	.	.	PUNCT
biomedich-691	33	1	this	this	DET
biomedich-691	33	2	process	process	NOUN
biomedich-691	33	3	uses	use	VERB
biomedich-691	33	4	pymol	pymol	PROPN
biomedich-691	33	5	software	software	NOUN
biomedich-691	33	6	to	to	PART
biomedich-691	33	7	find	find	VERB
biomedich-691	33	8	a	a	DET
biomedich-691	33	9	more	more	ADV
biomedich-691	33	10	specific	specific	ADJ
biomedich-691	33	11	sequence	sequence	NOUN
biomedich-691	33	12	.	.	PUNCT
biomedich-691	34	1	the	the	DET
biomedich-691	34	2	active	active	ADJ
biomedich-691	34	3	compound	compound	NOUN
biomedich-691	34	4	artocarpus	artocarpus	PROPN
biomedich-691	34	5	altilis	altili	NOUN
biomedich-691	34	6	became	become	VERB
biomedich-691	34	7	the	the	DET
biomedich-691	34	8	test	test	NOUN
biomedich-691	34	9	ligand	ligand	NOUN
biomedich-691	34	10	in	in	ADP
biomedich-691	34	11	this	this	DET
biomedich-691	34	12	study	study	NOUN
biomedich-691	34	13	,	,	PUNCT
biomedich-691	34	14	the	the	DET
biomedich-691	34	15	structure	structure	NOUN
biomedich-691	34	16	of	of	ADP
biomedich-691	34	17	each	each	DET
biomedich-691	34	18	compound	compound	NOUN
biomedich-691	34	19	was	be	AUX
biomedich-691	34	20	obtained	obtain	VERB
biomedich-691	34	21	through	through	ADP
biomedich-691	34	22	https://pubchem.ncbi.nlm.nih.gov/.	https://pubchem.ncbi.nlm.nih.gov/.	PROPN
biomedich-691	34	23	the	the	DET
biomedich-691	34	24	active	active	ADJ
biomedich-691	34	25	compounds	compound	NOUN
biomedich-691	34	26	used	use	VERB
biomedich-691	34	27	are	be	AUX
biomedich-691	34	28	:	:	PUNCT
biomedich-691	34	29	caffeic	caffeic	ADJ
biomedich-691	34	30	acid	acid	PROPN
biomedich-691	34	31	(	(	PUNCT
biomedich-691	34	32	689043	689043	NUM
biomedich-691	34	33	)	)	PUNCT
biomedich-691	34	34	,	,	PUNCT
biomedich-691	34	35	chlorogenic	chlorogenic	NOUN
biomedich-691	34	36	acid	acid	NOUN
biomedich-691	34	37	(	(	PUNCT
biomedich-691	34	38	1794427	1794427	NUM
biomedich-691	34	39	)	)	PUNCT
biomedich-691	34	40	,	,	PUNCT
biomedich-691	34	41	coumaric	coumaric	ADJ
biomedich-691	34	42	acid	acid	NOUN
biomedich-691	34	43	(	(	PUNCT
biomedich-691	34	44	637542	637542	NUM
biomedich-691	34	45	)	)	PUNCT
biomedich-691	34	46	,	,	PUNCT
biomedich-691	34	47	ferulic	ferulic	ADJ
biomedich-691	34	48	acid	acid	NOUN
biomedich-691	34	49	(	(	PUNCT
biomedich-691	34	50	445858	445858	NUM
biomedich-691	34	51	)	)	PUNCT
biomedich-691	34	52	,	,	PUNCT
biomedich-691	34	53	hyperoside	hyperoside	INTJ
biomedich-691	34	54	(	(	PUNCT
biomedich-691	34	55	5281643	5281643	NUM
biomedich-691	34	56	)	)	PUNCT
biomedich-691	34	57	,	,	PUNCT
biomedich-691	34	58	quercetin	quercetin	NOUN
biomedich-691	34	59	(	(	PUNCT
biomedich-691	34	60	5280343	5280343	NUM
biomedich-691	34	61	)	)	PUNCT
biomedich-691	34	62	,	,	PUNCT
biomedich-691	34	63	ellagic	ellagic	ADJ
biomedich-691	34	64	acid	acid	NOUN
biomedich-691	34	65	(	(	PUNCT
biomedich-691	34	66	5281855	5281855	NUM
biomedich-691	34	67	)	)	PUNCT
biomedich-691	34	68	,	,	PUNCT
biomedich-691	34	69	gallic	gallic	NOUN
biomedich-691	34	70	acid	acid	NOUN
biomedich-691	34	71	(	(	PUNCT
biomedich-691	34	72	370	370	NUM
biomedich-691	34	73	)	)	PUNCT
biomedich-691	34	74	,	,	PUNCT
biomedich-691	34	75	catechin	catechin	NOUN
biomedich-691	34	76	(	(	PUNCT
biomedich-691	34	77	9064	9064	NUM
biomedich-691	34	78	)	)	PUNCT
biomedich-691	34	79	,	,	PUNCT
biomedich-691	34	80	epicatechin	epicatechin	NOUN
biomedich-691	34	81	(	(	PUNCT
biomedich-691	34	82	72276	72276	NUM
biomedich-691	34	83	)	)	PUNCT
biomedich-691	34	84	,	,	PUNCT
biomedich-691	34	85	limonene	limonene	NOUN
biomedich-691	34	86	(	(	PUNCT
biomedich-691	34	87	22311	22311	NUM
biomedich-691	34	88	)	)	PUNCT
biomedich-691	34	89	,	,	PUNCT
biomedich-691	34	90	γ	γ	NOUN
biomedich-691	34	91	-	-	PUNCT
biomedich-691	34	92	terpinene	terpinene	NOUN
biomedich-691	34	93	(	(	PUNCT
biomedich-691	34	94	481107192	481107192	NUM
biomedich-691	34	95	)	)	PUNCT
biomedich-691	34	96	,	,	PUNCT
biomedich-691	34	97	terpinolene	terpinolene	NOUN
biomedich-691	34	98	(	(	PUNCT
biomedich-691	34	99	11463	11463	NUM
biomedich-691	34	100	)	)	PUNCT
biomedich-691	34	101	,	,	PUNCT
biomedich-691	34	102	and	and	CCONJ
biomedich-691	34	103	doxorubin	doxorubin	PROPN
biomedich-691	34	104	(	(	PUNCT
biomedich-691	34	105	31703	31703	NUM
biomedich-691	34	106	)	)	PUNCT
biomedich-691	34	107	as	as	ADP
biomedich-691	34	108	standard	standard	ADJ
biomedich-691	34	109	drugs	drug	NOUN
biomedich-691	34	110	.	.	PUNCT
biomedich-691	35	1	molecular	molecular	ADJ
biomedich-691	35	2	docking	docking	NOUN
biomedich-691	35	3	simulation	simulation	NOUN
biomedich-691	35	4	the	the	DET
biomedich-691	35	5	docking	docking	NOUN
biomedich-691	35	6	method	method	NOUN
biomedich-691	35	7	must	must	AUX
biomedich-691	35	8	be	be	AUX
biomedich-691	35	9	validated	validate	VERB
biomedich-691	35	10	using	use	VERB
biomedich-691	35	11	several	several	ADJ
biomedich-691	35	12	methods	method	NOUN
biomedich-691	35	13	,	,	PUNCT
biomedich-691	35	14	one	one	NUM
biomedich-691	35	15	of	of	ADP
biomedich-691	35	16	which	which	PRON
biomedich-691	35	17	is	be	AUX
biomedich-691	35	18	the	the	DET
biomedich-691	35	19	redocking	redocking	NOUN
biomedich-691	35	20	process	process	NOUN
biomedich-691	35	21	(	(	PUNCT
biomedich-691	35	22	dallakyan	dallakyan	PROPN
biomedich-691	35	23	&	&	CCONJ
biomedich-691	35	24	olson	olson	PROPN
biomedich-691	35	25	,	,	PUNCT
biomedich-691	35	26	2015	2015	NUM
biomedich-691	35	27	)	)	PUNCT
biomedich-691	35	28	.	.	PUNCT
biomedich-691	36	1	this	this	DET
biomedich-691	36	2	redocking	redocking	NOUN
biomedich-691	36	3	process	process	NOUN
biomedich-691	36	4	has	have	VERB
biomedich-691	36	5	parameters	parameter	NOUN
biomedich-691	36	6	that	that	PRON
biomedich-691	36	7	will	will	AUX
biomedich-691	36	8	show	show	VERB
biomedich-691	36	9	the	the	DET
biomedich-691	36	10	ligand	ligand	ADJ
biomedich-691	36	11	deviation	deviation	NOUN
biomedich-691	36	12	that	that	PRON
biomedich-691	36	13	occurs	occur	VERB
biomedich-691	36	14	during	during	ADP
biomedich-691	36	15	the	the	DET
biomedich-691	36	16	docking	docking	NOUN
biomedich-691	36	17	process	process	NOUN
biomedich-691	36	18	.	.	PUNCT
biomedich-691	37	1	the	the	DET
biomedich-691	37	2	validity	validity	NOUN
biomedich-691	37	3	parameter	parameter	NOUN
biomedich-691	37	4	of	of	ADP
biomedich-691	37	5	the	the	DET
biomedich-691	37	6	method	method	NOUN
biomedich-691	37	7	is	be	AUX
biomedich-691	37	8	the	the	DET
biomedich-691	37	9	root	root	NOUN
biomedich-691	37	10	mean	mean	ADJ
biomedich-691	37	11	square	square	ADJ
biomedich-691	37	12	deviation	deviation	NOUN
biomedich-691	37	13	(	(	PUNCT
biomedich-691	37	14	rmsd	rmsd	NOUN
biomedich-691	37	15	)	)	PUNCT
biomedich-691	37	16	with	with	ADP
biomedich-691	37	17	a	a	DET
biomedich-691	37	18	maximum	maximum	ADJ
biomedich-691	37	19	value	value	NOUN
biomedich-691	37	20	of	of	ADP
biomedich-691	37	21	less	less	ADJ
biomedich-691	37	22	than	than	ADP
biomedich-691	37	23	2	2	NUM
biomedich-691	37	24	å	å	PROPN
biomedich-691	37	25	,	,	PUNCT
biomedich-691	37	26	the	the	PRON
biomedich-691	37	27	lower	low	ADJ
biomedich-691	37	28	the	the	DET
biomedich-691	37	29	value	value	NOUN
biomedich-691	37	30	,	,	PUNCT
biomedich-691	37	31	the	the	DET
biomedich-691	37	32	better	well	ADJ
biomedich-691	37	33	.	.	PUNCT
biomedich-691	38	1	this	this	DET
biomedich-691	38	2	process	process	NOUN
biomedich-691	38	3	is	be	AUX
biomedich-691	38	4	needed	need	VERB
biomedich-691	38	5	to	to	PART
biomedich-691	38	6	determine	determine	VERB
biomedich-691	38	7	the	the	DET
biomedich-691	38	8	location	location	NOUN
biomedich-691	38	9	and	and	CCONJ
biomedich-691	38	10	size	size	NOUN
biomedich-691	38	11	of	of	ADP
biomedich-691	38	12	the	the	DET
biomedich-691	38	13	grid	grid	PROPN
biomedich-691	38	14	box	box	PROPN
biomedich-691	38	15	(	(	PUNCT
biomedich-691	38	16	x	x	PROPN
biomedich-691	38	17	,	,	PUNCT
biomedich-691	38	18	y	y	PROPN
biomedich-691	38	19	,	,	PUNCT
biomedich-691	38	20	z	z	NOUN
biomedich-691	38	21	)	)	PUNCT
biomedich-691	38	22	of	of	ADP
biomedich-691	38	23	the	the	DET
biomedich-691	38	24	native	native	ADJ
biomedich-691	38	25	ligand	ligand	NOUN
biomedich-691	38	26	,	,	PUNCT
biomedich-691	38	27	as	as	ADP
biomedich-691	38	28	a	a	DET
biomedich-691	38	29	reference	reference	NOUN
biomedich-691	38	30	in	in	ADP
biomedich-691	38	31	specific	specific	ADJ
biomedich-691	38	32	docking	docking	NOUN
biomedich-691	38	33	(	(	PUNCT
biomedich-691	38	34	dai	dai	PROPN
biomedich-691	38	35	et	et	PROPN
biomedich-691	38	36	al	al	PROPN
biomedich-691	38	37	.	.	PROPN
biomedich-691	38	38	,	,	PUNCT
biomedich-691	38	39	2018	2018	NUM
biomedich-691	38	40	)	)	PUNCT
biomedich-691	38	41	.	.	PUNCT
biomedich-691	39	1	the	the	DET
biomedich-691	39	2	redocking	redocking	NOUN
biomedich-691	39	3	process	process	NOUN
biomedich-691	39	4	uses	use	VERB
biomedich-691	39	5	the	the	DET
biomedich-691	39	6	vina	vina	NOUN
biomedich-691	39	7	tool	tool	NOUN
biomedich-691	39	8	as	as	ADP
biomedich-691	39	9	a	a	DET
biomedich-691	39	10	docking	docking	NOUN
biomedich-691	39	11	process	process	NOUN
biomedich-691	39	12	runner	runner	NOUN
biomedich-691	39	13	in	in	ADP
biomedich-691	39	14	the	the	DET
biomedich-691	39	15	pyrx	pyrx	NOUN
biomedich-691	39	16	application	application	NOUN
biomedich-691	39	17	.	.	PUNCT
biomedich-691	40	1	the	the	DET
biomedich-691	40	2	open	open	ADJ
biomedich-691	40	3	babel	babel	NOUN
biomedich-691	40	4	tool	tool	NOUN
biomedich-691	40	5	in	in	ADP
biomedich-691	40	6	pyrx	pyrx	NOUN
biomedich-691	40	7	is	be	AUX
biomedich-691	40	8	used	use	VERB
biomedich-691	40	9	as	as	ADP
biomedich-691	40	10	a	a	DET
biomedich-691	40	11	converter	converter	NOUN
biomedich-691	40	12	of	of	ADP
biomedich-691	40	13	ligand	ligand	NOUN
biomedich-691	40	14	and	and	CCONJ
biomedich-691	40	15	receptor	receptor	NOUN
biomedich-691	40	16	files	file	NOUN
biomedich-691	40	17	to	to	PART
biomedich-691	40	18	pdbqt	pdbqt	VERB
biomedich-691	40	19	.	.	PUNCT
biomedich-691	41	1	this	this	DET
biomedich-691	41	2	tool	tool	NOUN
biomedich-691	41	3	is	be	AUX
biomedich-691	41	4	also	also	ADV
biomedich-691	41	5	used	use	VERB
biomedich-691	41	6	to	to	PART
biomedich-691	41	7	minimize	minimize	VERB
biomedich-691	41	8	the	the	DET
biomedich-691	41	9	energy	energy	NOUN
biomedich-691	41	10	of	of	ADP
biomedich-691	41	11	each	each	DET
biomedich-691	41	12	compound	compound	NOUN
biomedich-691	41	13	in	in	ADP
biomedich-691	41	14	order	order	NOUN
biomedich-691	41	15	to	to	PART
biomedich-691	41	16	obtain	obtain	VERB
biomedich-691	41	17	the	the	DET
biomedich-691	41	18	lowest	low	ADJ
biomedich-691	41	19	energy	energy	NOUN
biomedich-691	41	20	of	of	ADP
biomedich-691	41	21	the	the	DET
biomedich-691	41	22	compound	compound	NOUN
biomedich-691	41	23	during	during	ADP
biomedich-691	41	24	the	the	DET
biomedich-691	41	25	docking	docking	NOUN
biomedich-691	41	26	process	process	NOUN
biomedich-691	41	27	.	.	PUNCT
biomedich-691	42	1	the	the	DET
biomedich-691	42	2	docking	docking	NOUN
biomedich-691	42	3	simulation	simulation	NOUN
biomedich-691	42	4	process	process	NOUN
biomedich-691	42	5	uses	use	VERB
biomedich-691	42	6	the	the	DET
biomedich-691	42	7	same	same	ADJ
biomedich-691	42	8	method	method	NOUN
biomedich-691	42	9	by	by	ADP
biomedich-691	42	10	adjusting	adjust	VERB
biomedich-691	42	11	the	the	DET
biomedich-691	42	12	location	location	NOUN
biomedich-691	42	13	and	and	CCONJ
biomedich-691	42	14	size	size	NOUN
biomedich-691	42	15	of	of	ADP
biomedich-691	42	16	the	the	DET
biomedich-691	42	17	native	native	ADJ
biomedich-691	42	18	ligand	ligand	PROPN
biomedich-691	42	19	grid	grid	PROPN
biomedich-691	42	20	box	box	PROPN
biomedich-691	42	21	.	.	PUNCT
biomedich-691	43	1	evaluation	evaluation	NOUN
biomedich-691	43	2	of	of	ADP
biomedich-691	43	3	the	the	DET
biomedich-691	43	4	docking	docking	NOUN
biomedich-691	43	5	results	result	NOUN
biomedich-691	43	6	in	in	ADP
biomedich-691	43	7	the	the	DET
biomedich-691	43	8	form	form	NOUN
biomedich-691	43	9	of	of	ADP
biomedich-691	43	10	binding	bind	VERB
biomedich-691	43	11	affinity	affinity	NOUN
biomedich-691	43	12	formed	form	VERB
biomedich-691	43	13	during	during	ADP
biomedich-691	43	14	the	the	DET
biomedich-691	43	15	docking	docking	NOUN
biomedich-691	43	16	simulation	simulation	NOUN
biomedich-691	43	17	process	process	NOUN
biomedich-691	43	18	.	.	PUNCT
biomedich-691	44	1	low	low	ADJ
biomedich-691	44	2	binding	bind	VERB
biomedich-691	44	3	affinity	affinity	NOUN
biomedich-691	44	4	indicates	indicate	VERB
biomedich-691	44	5	good	good	ADJ
biomedich-691	44	6	interaction	interaction	NOUN
biomedich-691	44	7	ability	ability	NOUN
biomedich-691	44	8	of	of	ADP
biomedich-691	44	9	the	the	DET
biomedich-691	44	10	ligand	ligand	NOUN
biomedich-691	44	11	with	with	ADP
biomedich-691	44	12	the	the	DET
biomedich-691	44	13	protein	protein	NOUN
biomedich-691	44	14	(	(	PUNCT
biomedich-691	44	15	hassan	hassan	PROPN
biomedich-691	44	16	et	et	PROPN
biomedich-691	44	17	al	al	PROPN
biomedich-691	44	18	.	.	PROPN
biomedich-691	44	19	,	,	PUNCT
biomedich-691	44	20	2020	2020	NUM
biomedich-691	44	21	)	)	PUNCT
biomedich-691	44	22	.	.	PUNCT
biomedich-691	45	1	visualization	visualization	NOUN
biomedich-691	45	2	of	of	ADP
biomedich-691	45	3	results	result	NOUN
biomedich-691	45	4	the	the	DET
biomedich-691	45	5	results	result	NOUN
biomedich-691	45	6	of	of	ADP
biomedich-691	45	7	the	the	DET
biomedich-691	45	8	redocking	redocking	NOUN
biomedich-691	45	9	process	process	NOUN
biomedich-691	45	10	were	be	AUX
biomedich-691	45	11	calculated	calculate	VERB
biomedich-691	45	12	using	use	VERB
biomedich-691	45	13	rmsd	rmsd	NOUN
biomedich-691	45	14	and	and	CCONJ
biomedich-691	45	15	visualized	visualize	VERB
biomedich-691	45	16	the	the	DET
biomedich-691	45	17	overlap	overlap	NOUN
biomedich-691	45	18	between	between	ADP
biomedich-691	45	19	the	the	DET
biomedich-691	45	20	ligand	ligand	NOUN
biomedich-691	45	21	before	before	ADV
biomedich-691	45	22	and	and	CCONJ
biomedich-691	45	23	after	after	ADP
biomedich-691	45	24	the	the	DET
biomedich-691	45	25	docking	docking	NOUN
biomedich-691	45	26	process	process	NOUN
biomedich-691	45	27	using	use	VERB
biomedich-691	45	28	pymol	pymol	PROPN
biomedich-691	45	29	software	software	NOUN
biomedich-691	45	30	and	and	CCONJ
biomedich-691	45	31	biovia	biovia	NOUN
biomedich-691	45	32	discovery	discovery	PROPN
biomedich-691	45	33	studio	studio	PROPN
biomedich-691	45	34	2021	2021	NUM
biomedich-691	45	35	.	.	PUNCT
biomedich-691	46	1	(	(	PUNCT
biomedich-691	46	2	lestariningrum	lestariningrum	NOUN
biomedich-691	46	3	et	et	PROPN
biomedich-691	46	4	al	al	PROPN
biomedich-691	46	5	.	.	PROPN
biomedich-691	46	6	,	,	PUNCT
biomedich-691	46	7	2024)visualization	2024)visualization	NOUN
biomedich-691	46	8	of	of	ADP
biomedich-691	46	9	the	the	DET
biomedich-691	46	10	docking	docking	NOUN
biomedich-691	46	11	results	result	NOUN
biomedich-691	46	12	was	be	AUX
biomedich-691	46	13	used	use	VERB
biomedich-691	46	14	as	as	ADP
biomedich-691	46	15	an	an	DET
biomedich-691	46	16	analysis	analysis	NOUN
biomedich-691	46	17	of	of	ADP
biomedich-691	46	18	the	the	DET
biomedich-691	46	19	interaction	interaction	NOUN
biomedich-691	46	20	of	of	ADP
biomedich-691	46	21	amino	amino	NOUN
biomedich-691	46	22	acid	acid	NOUN
biomedich-691	46	23	residues	residue	NOUN
biomedich-691	46	24	formed	form	VERB
biomedich-691	46	25	between	between	ADP
biomedich-691	46	26	the	the	DET
biomedich-691	46	27	ligand	ligand	NOUN
biomedich-691	46	28	and	and	CCONJ
biomedich-691	46	29	the	the	DET
biomedich-691	46	30	receptor	receptor	NOUN
biomedich-691	46	31	.	.	PUNCT
biomedich-691	47	1	visualization	visualization	NOUN
biomedich-691	47	2	of	of	ADP
biomedich-691	47	3	amino	amino	NOUN
biomedich-691	47	4	acid	acid	NOUN
biomedich-691	47	5	interactions	interaction	NOUN
biomedich-691	47	6	using	use	VERB
biomedich-691	47	7	the	the	DET
biomedich-691	47	8	ligplus	ligplus	ADJ
biomedich-691	47	9	application	application	NOUN
biomedich-691	47	10	which	which	PRON
biomedich-691	47	11	shows	show	VERB
biomedich-691	47	12	the	the	DET
biomedich-691	47	13	hydrogen	hydrogen	NOUN
biomedich-691	47	14	and	and	CCONJ
biomedich-691	47	15	non	non	ADJ
biomedich-691	47	16	-	-	ADJ
biomedich-691	47	17	hydrogen	hydrogen	ADJ
biomedich-691	47	18	bonds	bond	NOUN
biomedich-691	47	19	formed	form	VERB
biomedich-691	47	20	(	(	PUNCT
biomedich-691	47	21	afladhanti	afladhanti	X
biomedich-691	47	22	et	et	PROPN
biomedich-691	47	23	al	al	PROPN
biomedich-691	47	24	.	.	PROPN
biomedich-691	47	25	,	,	PUNCT
biomedich-691	47	26	2023	2023	NUM
biomedich-691	47	27	)	)	PUNCT
biomedich-691	47	28	.	.	PUNCT
biomedich-691	48	1	prediction	prediction	NOUN
biomedich-691	48	2	of	of	ADP
biomedich-691	48	3	pharmacokinetics	pharmacokinetic	NOUN
biomedich-691	48	4	,	,	PUNCT
biomedich-691	48	5	toxicity	toxicity	NOUN
biomedich-691	48	6	and	and	CCONJ
biomedich-691	48	7	physicochemistry	physicochemistry	NOUN
biomedich-691	48	8	of	of	ADP
biomedich-691	48	9	test	test	NOUN
biomedich-691	48	10	compounds	compound	VERB
biomedich-691	48	11	pharmacokinetic	pharmacokinetic	ADJ
biomedich-691	48	12	and	and	CCONJ
biomedich-691	48	13	toxicity	toxicity	NOUN
biomedich-691	48	14	predictions	prediction	NOUN
biomedich-691	48	15	use	use	VERB
biomedich-691	48	16	admet	admet	NOUN
biomedich-691	48	17	parameters	parameter	NOUN
biomedich-691	48	18	that	that	PRON
biomedich-691	48	19	can	can	AUX
biomedich-691	48	20	be	be	AUX
biomedich-691	48	21	accessed	access	VERB
biomedich-691	48	22	through	through	ADP
biomedich-691	48	23	https://biosig.lab.uq.edu.au/pkcsm/prediction	https://biosig.lab.uq.edu.au/pkcsm/prediction	NOUN
biomedich-691	48	24	.	.	PUNCT
biomedich-691	49	1	this	this	DET
biomedich-691	49	2	prediction	prediction	NOUN
biomedich-691	49	3	requires	require	VERB
biomedich-691	49	4	canonical	canonical	ADJ
biomedich-691	49	5	smiles	smile	NOUN
biomedich-691	49	6	for	for	ADP
biomedich-691	49	7	each	each	DET
biomedich-691	49	8	compound	compound	NOUN
biomedich-691	49	9	as	as	SCONJ
biomedich-691	49	10	an	an	DET
biomedich-691	49	11	analysis	analysis	NOUN
biomedich-691	49	12	format	format	NOUN
biomedich-691	49	13	obtained	obtain	VERB
biomedich-691	49	14	through	through	ADP
biomedich-691	49	15	https://pubchem.ncbi.nlm.nih.gov/.	https://pubchem.ncbi.nlm.nih.gov/.	ADJ
biomedich-691	49	16	physicochemical	physicochemical	ADJ
biomedich-691	49	17	predictions	prediction	NOUN
biomedich-691	49	18	can	can	AUX
biomedich-691	49	19	be	be	AUX
biomedich-691	49	20	accessed	access	VERB
biomedich-691	49	21	through	through	ADP
biomedich-691	49	22	http://www.swissadme.ch/index.php	http://www.swissadme.ch/index.php	INTJ
biomedich-691	49	23	by	by	ADP
biomedich-691	49	24	ensuring	ensure	VERB
biomedich-691	49	25	canonical	canonical	ADJ
biomedich-691	49	26	smiles	smile	NOUN
biomedich-691	49	27	for	for	ADP
biomedich-691	49	28	each	each	DET
biomedich-691	49	29	compound	compound	NOUN
biomedich-691	49	30	.	.	PUNCT
biomedich-691	50	1	the	the	DET
biomedich-691	50	2	parameters	parameter	NOUN
biomedich-691	50	3	used	use	VERB
biomedich-691	50	4	in	in	ADP
biomedich-691	50	5	physicochemical	physicochemical	ADJ
biomedich-691	50	6	predictions	prediction	NOUN
biomedich-691	50	7	are	be	AUX
biomedich-691	50	8	lipinski	lipinski	PROPN
biomedich-691	50	9	rules	rule	NOUN
biomedich-691	50	10	which	which	PRON
biomedich-691	50	11	are	be	AUX
biomedich-691	50	12	common	common	ADJ
biomedich-691	50	13	parameters	parameter	NOUN
biomedich-691	50	14	used	use	VERB
biomedich-691	50	15	in	in	ADP
biomedich-691	50	16	the	the	DET
biomedich-691	50	17	development	development	NOUN
biomedich-691	50	18	of	of	ADP
biomedich-691	50	19	a	a	DET
biomedich-691	50	20	new	new	ADJ
biomedich-691	50	21	oral	oral	ADJ
biomedich-691	50	22	drug	drug	NOUN
biomedich-691	50	23	(	(	PUNCT
biomedich-691	50	24	dong	dong	NOUN
biomedich-691	50	25	et	et	PROPN
biomedich-691	50	26	al	al	PROPN
biomedich-691	50	27	.	.	PROPN
biomedich-691	50	28	,	,	PUNCT
biomedich-691	50	29	2018	2018	NUM
biomedich-691	50	30	)	)	PUNCT
biomedich-691	50	31	.	.	PUNCT
biomedich-691	51	1	results	result	NOUN
biomedich-691	51	2	and	and	CCONJ
biomedich-691	51	3	discussion	discussion	NOUN
biomedich-691	51	4	docking	dock	VERB
biomedich-691	51	5	analysis	analysis	NOUN
biomedich-691	51	6	the	the	DET
biomedich-691	51	7	validation	validation	NOUN
biomedich-691	51	8	results	result	NOUN
biomedich-691	51	9	of	of	ADP
biomedich-691	51	10	the	the	DET
biomedich-691	51	11	docking	docking	NOUN
biomedich-691	51	12	method	method	NOUN
biomedich-691	51	13	using	use	VERB
biomedich-691	51	14	pyrx	pyrx	NOUN
biomedich-691	51	15	showed	show	VERB
biomedich-691	51	16	that	that	SCONJ
biomedich-691	51	17	the	the	DET
biomedich-691	51	18	root	root	NOUN
biomedich-691	51	19	mean	mean	VERB
biomedich-691	51	20	square	square	ADJ
biomedich-691	51	21	deviation	deviation	NOUN
biomedich-691	51	22	(	(	PUNCT
biomedich-691	51	23	rmsd	rmsd	NOUN
biomedich-691	51	24	)	)	PUNCT
biomedich-691	51	25	value	value	NOUN
biomedich-691	51	26	reached	reach	VERB
biomedich-691	51	27	0.854	0.854	NUM
biomedich-691	51	28	å	å	NOUN
biomedich-691	51	29	,	,	PUNCT
biomedich-691	51	30	indicating	indicate	VERB
biomedich-691	51	31	the	the	DET
biomedich-691	51	32	high	high	ADJ
biomedich-691	51	33	accuracy	accuracy	NOUN
biomedich-691	51	34	of	of	ADP
biomedich-691	51	35	the	the	DET
biomedich-691	51	36	docking	docking	NOUN
biomedich-691	51	37	model	model	NOUN
biomedich-691	51	38	used	use	VERB
biomedich-691	51	39	(	(	PUNCT
biomedich-691	51	40	dallakyan	dallakyan	PROPN
biomedich-691	51	41	&	&	CCONJ
biomedich-691	51	42	olson	olson	PROPN
biomedich-691	51	43	,	,	PUNCT
biomedich-691	51	44	2015	2015	NUM
biomedich-691	51	45	)	)	PUNCT
biomedich-691	51	46	.	.	PUNCT
biomedich-691	52	1	the	the	DET
biomedich-691	52	2	validation	validation	NOUN
biomedich-691	52	3	results	result	NOUN
biomedich-691	52	4	of	of	ADP
biomedich-691	52	5	the	the	DET
biomedich-691	52	6	docking	docking	NOUN
biomedich-691	52	7	method	method	NOUN
biomedich-691	52	8	using	use	VERB
biomedich-691	52	9	pyrx	pyrx	NOUN
biomedich-691	52	10	showed	show	VERB
biomedich-691	52	11	that	that	SCONJ
biomedich-691	52	12	the	the	DET
biomedich-691	52	13	root	root	NOUN
biomedich-691	52	14	mean	mean	VERB
biomedich-691	52	15	square	square	ADJ
biomedich-691	52	16	deviation	deviation	NOUN
biomedich-691	52	17	(	(	PUNCT
biomedich-691	52	18	rmsd	rmsd	NOUN
biomedich-691	52	19	)	)	PUNCT
biomedich-691	52	20	value	value	NOUN
biomedich-691	52	21	reached	reach	VERB
biomedich-691	52	22	0.854	0.854	NUM
biomedich-691	52	23	å	å	PROPN
biomedich-691	52	24	,	,	PUNCT
biomedich-691	52	25	which	which	PRON
biomedich-691	52	26	is	be	AUX
biomedich-691	52	27	far	far	ADV
biomedich-691	52	28	below	below	ADP
biomedich-691	52	29	the	the	DET
biomedich-691	52	30	maximum	maximum	ADJ
biomedich-691	52	31	limit	limit	NOUN
biomedich-691	52	32	of	of	ADP
biomedich-691	52	33	less	less	ADJ
biomedich-691	52	34	than	than	ADP
biomedich-691	52	35	2	2	NUM
biomedich-691	52	36	å	å	NOUN
biomedich-691	52	37	,	,	PUNCT
biomedich-691	52	38	indicating	indicate	VERB
biomedich-691	52	39	the	the	DET
biomedich-691	52	40	high	high	ADJ
biomedich-691	52	41	accuracy	accuracy	NOUN
biomedich-691	52	42	of	of	ADP
biomedich-691	52	43	the	the	DET
biomedich-691	52	44	resulting	result	VERB
biomedich-691	52	45	docking	docking	NOUN
biomedich-691	52	46	model	model	NOUN
biomedich-691	52	47	.	.	PUNCT
biomedich-691	53	1	this	this	DET
biomedich-691	53	2	process	process	NOUN
biomedich-691	53	3	is	be	AUX
biomedich-691	53	4	important	important	ADJ
biomedich-691	53	5	to	to	PART
biomedich-691	53	6	determine	determine	VERB
biomedich-691	53	7	the	the	DET
biomedich-691	53	8	position	position	NOUN
biomedich-691	53	9	and	and	CCONJ
biomedich-691	53	10	size	size	NOUN
biomedich-691	53	11	of	of	ADP
biomedich-691	53	12	the	the	DET
biomedich-691	53	13	grid	grid	PROPN
biomedich-691	53	14	box	box	PROPN
biomedich-691	53	15	(	(	PUNCT
biomedich-691	53	16	x	x	PROPN
biomedich-691	53	17	,	,	PUNCT
biomedich-691	53	18	y	y	PROPN
biomedich-691	53	19	,	,	PUNCT
biomedich-691	53	20	z	z	NOUN
biomedich-691	53	21	)	)	PUNCT
biomedich-691	53	22	of	of	ADP
biomedich-691	53	23	the	the	DET
biomedich-691	53	24	original	original	ADJ
biomedich-691	53	25	ligand	ligand	NOUN
biomedich-691	53	26	as	as	ADP
biomedich-691	53	27	a	a	DET
biomedich-691	53	28	reference	reference	NOUN
biomedich-691	53	29	for	for	ADP
biomedich-691	53	30	specific	specific	ADJ
biomedich-691	53	31	docking	docking	NOUN
biomedich-691	53	32	to	to	ADP
biomedich-691	53	33	the	the	DET
biomedich-691	53	34	target	target	NOUN
biomedich-691	53	35	protein	protein	NOUN
biomedich-691	53	36	.	.	PUNCT
biomedich-691	54	1	this	this	DET
biomedich-691	54	2	analysis	analysis	NOUN
biomedich-691	54	3	shows	show	VERB
biomedich-691	54	4	that	that	SCONJ
biomedich-691	54	5	the	the	DET
biomedich-691	54	6	ligand	ligand	ADJ
biomedich-691	54	7	structure	structure	NOUN
biomedich-691	54	8	has	have	AUX
biomedich-691	54	9	been	be	AUX
biomedich-691	54	10	well	well	ADV
biomedich-691	54	11	integrated	integrate	VERB
biomedich-691	54	12	into	into	ADP
biomedich-691	54	13	the	the	DET
biomedich-691	54	14	active	active	ADJ
biomedich-691	54	15	site	site	NOUN
biomedich-691	54	16	of	of	ADP
biomedich-691	54	17	the	the	DET
biomedich-691	54	18	target	target	NOUN
biomedich-691	54	19	protein	protein	NOUN
biomedich-691	54	20	,	,	PUNCT
biomedich-691	54	21	with	with	ADP
biomedich-691	54	22	the	the	DET
biomedich-691	54	23	center	center	ADJ
biomedich-691	54	24	position	position	NOUN
biomedich-691	54	25	of	of	ADP
biomedich-691	54	26	the	the	DET
biomedich-691	54	27	grid	grid	NOUN
biomedich-691	54	28	box	box	PROPN
biomedich-691	54	29	at	at	ADP
biomedich-691	54	30	coordinates	coordinate	NOUN
biomedich-691	54	31	x	x	PUNCT
biomedich-691	54	32	=	=	SYM
biomedich-691	54	33	-52.555	-52.555	PROPN
biomedich-691	54	34	,	,	PUNCT
biomedich-691	54	35	y	y	PROPN
biomedich-691	54	36	=	=	NOUN
biomedich-691	54	37	0.208	0.208	NUM
biomedich-691	54	38	,	,	PUNCT
biomedich-691	54	39	and	and	CCONJ
biomedich-691	54	40	z	z	NOUN
biomedich-691	54	41	=	=	SYM
biomedich-691	54	42	-19.899	-19.899	NOUN
biomedich-691	54	43	,	,	PUNCT
biomedich-691	54	44	and	and	CCONJ
biomedich-691	54	45	the	the	DET
biomedich-691	54	46	grid	grid	NOUN
biomedich-691	54	47	box	box	NOUN
biomedich-691	54	48	sizes	size	NOUN
biomedich-691	54	49	are	be	AUX
biomedich-691	54	50	x	x	X
biomedich-691	54	51	=	=	SYM
biomedich-691	54	52	13.673	13.673	NUM
biomedich-691	54	53	,	,	PUNCT
biomedich-691	54	54	y	y	PROPN
biomedich-691	54	55	=	=	SYM
biomedich-691	54	56	11.664	11.664	NUM
biomedich-691	54	57	,	,	PUNCT
biomedich-691	54	58	and	and	CCONJ
biomedich-691	54	59	z	z	NOUN
biomedich-691	54	60	=	=	SYM
biomedich-691	54	61	21.900	21.900	NUM
biomedich-691	54	62	,	,	PUNCT
biomedich-691	54	63	respectively	respectively	ADV
biomedich-691	54	64	.	.	PUNCT
biomedich-691	55	1	this	this	DET
biomedich-691	55	2	information	information	NOUN
biomedich-691	55	3	is	be	AUX
biomedich-691	55	4	very	very	ADV
biomedich-691	55	5	important	important	ADJ
biomedich-691	55	6	to	to	PART
biomedich-691	55	7	continue	continue	VERB
biomedich-691	55	8	the	the	DET
biomedich-691	55	9	specific	specific	ADJ
biomedich-691	55	10	docking	docking	NOUN
biomedich-691	55	11	steps	step	NOUN
biomedich-691	55	12	,	,	PUNCT
biomedich-691	55	13	ensuring	ensure	VERB
biomedich-691	55	14	that	that	SCONJ
biomedich-691	55	15	the	the	DET
biomedich-691	55	16	simulation	simulation	NOUN
biomedich-691	55	17	is	be	AUX
biomedich-691	55	18	carried	carry	VERB
biomedich-691	55	19	out	out	ADP
biomedich-691	55	20	in	in	ADP
biomedich-691	55	21	the	the	DET
biomedich-691	55	22	right	right	ADJ
biomedich-691	55	23	area	area	NOUN
biomedich-691	55	24	.	.	PUNCT
biomedich-691	56	1	in	in	ADP
biomedich-691	56	2	addition	addition	NOUN
biomedich-691	56	3	,	,	PUNCT
biomedich-691	56	4	molecular	molecular	ADJ
biomedich-691	56	5	docking	docking	NOUN
biomedich-691	56	6	analysis	analysis	NOUN
biomedich-691	56	7	revealed	reveal	VERB
biomedich-691	56	8	that	that	SCONJ
biomedich-691	56	9	the	the	DET
biomedich-691	56	10	active	active	ADJ
biomedich-691	56	11	compounds	compound	NOUN
biomedich-691	56	12	from	from	ADP
biomedich-691	56	13	artocarpus	artocarpus	PROPN
biomedich-691	56	14	altilis	altili	NOUN
biomedich-691	56	15	have	have	VERB
biomedich-691	56	16	good	good	ADJ
biomedich-691	56	17	affinity	affinity	NOUN
biomedich-691	56	18	values	value	NOUN
biomedich-691	56	19	for	for	ADP
biomedich-691	56	20	the	the	DET
biomedich-691	56	21	target	target	NOUN
biomedich-691	56	22	protein	protein	NOUN
biomedich-691	56	23	,	,	PUNCT
biomedich-691	56	24	as	as	SCONJ
biomedich-691	56	25	listed	list	VERB
biomedich-691	56	26	in	in	ADP
biomedich-691	56	27	table	table	NOUN
biomedich-691	56	28	1	1	NUM
biomedich-691	56	29	of	of	ADP
biomedich-691	56	30	the	the	DET
biomedich-691	56	31	analysis	analysis	NOUN
biomedich-691	56	32	results	result	NOUN
biomedich-691	56	33	.	.	PUNCT
biomedich-691	57	1	the	the	DET
biomedich-691	57	2	results	result	NOUN
biomedich-691	57	3	of	of	ADP
biomedich-691	57	4	the	the	DET
biomedich-691	57	5	molecular	molecular	ADJ
biomedich-691	57	6	docking	docking	NOUN
biomedich-691	57	7	analysis	analysis	NOUN
biomedich-691	57	8	showed	show	VERB
biomedich-691	57	9	that	that	SCONJ
biomedich-691	57	10	ellagic	ellagic	ADJ
biomedich-691	57	11	acid	acid	NOUN
biomedich-691	57	12	was	be	AUX
biomedich-691	57	13	the	the	DET
biomedich-691	57	14	ligand	ligand	NOUN
biomedich-691	57	15	with	with	ADP
biomedich-691	57	16	the	the	DET
biomedich-691	57	17	highest	high	ADJ
biomedich-691	57	18	affinity	affinity	NOUN
biomedich-691	57	19	for	for	ADP
biomedich-691	57	20	the	the	DET
biomedich-691	57	21	target	target	NOUN
biomedich-691	57	22	protein	protein	NOUN
biomedich-691	57	23	,	,	PUNCT
biomedich-691	57	24	with	with	ADP
biomedich-691	57	25	a	a	DET
biomedich-691	57	26	δg	δg	ADJ
biomedich-691	57	27	value	value	NOUN
biomedich-691	57	28	of	of	ADP
biomedich-691	57	29	-8.4	-8.4	X
biomedich-691	57	30	kcal	kcal	NOUN
biomedich-691	57	31	/	/	SYM
biomedich-691	57	32	mol	mol	PROPN
biomedich-691	57	33	.	.	PUNCT
biomedich-691	58	1	this	this	DET
biomedich-691	58	2	finding	finding	NOUN
biomedich-691	58	3	confirms	confirm	VERB
biomedich-691	58	4	the	the	DET
biomedich-691	58	5	potential	potential	NOUN
biomedich-691	58	6	of	of	ADP
biomedich-691	58	7	caffeic	caffeic	VERB
biomedich-691	58	8	acid	acid	NOUN
biomedich-691	58	9	as	as	ADP
biomedich-691	58	10	a	a	DET
biomedich-691	58	11	potent	potent	ADJ
biomedich-691	58	12	therapeutic	therapeutic	ADJ
biomedich-691	58	13	agent	agent	NOUN
biomedich-691	58	14	,	,	PUNCT
biomedich-691	58	15	capable	capable	ADJ
biomedich-691	58	16	of	of	ADP
biomedich-691	58	17	interacting	interact	VERB
biomedich-691	58	18	effectively	effectively	ADV
biomedich-691	58	19	with	with	ADP
biomedich-691	58	20	the	the	DET
biomedich-691	58	21	target	target	NOUN
biomedich-691	58	22	protein	protein	NOUN
biomedich-691	58	23	.	.	PUNCT
biomedich-691	59	1	quercetin	quercetin	NOUN
biomedich-691	59	2	showed	show	VERB
biomedich-691	59	3	good	good	ADJ
biomedich-691	59	4	interaction	interaction	NOUN
biomedich-691	59	5	,	,	PUNCT
biomedich-691	59	6	after	after	ADP
biomedich-691	59	7	that	that	PRON
biomedich-691	59	8	of	of	ADP
biomedich-691	59	9	ellagic	ellagic	ADJ
biomedich-691	59	10	acid	acid	NOUN
biomedich-691	59	11	with	with	ADP
biomedich-691	59	12	a	a	DET
biomedich-691	59	13	δg	δg	NOUN
biomedich-691	59	14	value	value	NOUN
biomedich-691	59	15	of	of	ADP
biomedich-691	59	16	-7.3	-7.3	PROPN
biomedich-691	59	17	kcal	kcal	PROPN
biomedich-691	59	18	/	/	SYM
biomedich-691	59	19	mol	mol	PROPN
biomedich-691	59	20	.	.	PUNCT
biomedich-691	60	1	this	this	DET
biomedich-691	60	2	potential	potential	NOUN
biomedich-691	60	3	is	be	AUX
biomedich-691	60	4	reinforced	reinforce	VERB
biomedich-691	60	5	by	by	ADP
biomedich-691	60	6	the	the	DET
biomedich-691	60	7	low	low	ADJ
biomedich-691	60	8	δg	δg	NOUN
biomedich-691	60	9	value	value	NOUN
biomedich-691	60	10	,	,	PUNCT
biomedich-691	60	11	indicating	indicate	VERB
biomedich-691	60	12	that	that	SCONJ
biomedich-691	60	13	caffeic	caffeic	VERB
biomedich-691	60	14	acid	acid	NOUN
biomedich-691	60	15	and	and	CCONJ
biomedich-691	60	16	quercetin	quercetin	NOUN
biomedich-691	60	17	can	can	AUX
biomedich-691	60	18	significantly	significantly	ADV
biomedich-691	60	19	inhibit	inhibit	VERB
biomedich-691	60	20	egfr	egfr	ADJ
biomedich-691	60	21	protein	protein	NOUN
biomedich-691	60	22	activity	activity	NOUN
biomedich-691	60	23	,	,	PUNCT
biomedich-691	60	24	making	make	VERB
biomedich-691	60	25	them	they	PRON
biomedich-691	60	26	attractive	attractive	ADJ
biomedich-691	60	27	candidates	candidate	NOUN
biomedich-691	60	28	in	in	ADP
biomedich-691	60	29	the	the	DET
biomedich-691	60	30	development	development	NOUN
biomedich-691	60	31	of	of	ADP
biomedich-691	60	32	new	new	ADJ
biomedich-691	60	33	drugs	drug	NOUN
biomedich-691	60	34	.	.	PUNCT
biomedich-691	61	1	this	this	PRON
biomedich-691	61	2	indicates	indicate	VERB
biomedich-691	61	3	that	that	SCONJ
biomedich-691	61	4	although	although	SCONJ
biomedich-691	61	5	their	their	PRON
biomedich-691	61	6	affinity	affinity	NOUN
biomedich-691	61	7	is	be	AUX
biomedich-691	61	8	lower	low	ADJ
biomedich-691	61	9	than	than	ADP
biomedich-691	61	10	ellagic	ellagic	ADJ
biomedich-691	61	11	acid	acid	NOUN
biomedich-691	61	12	,	,	PUNCT
biomedich-691	61	13	both	both	PRON
biomedich-691	61	14	still	still	ADV
biomedich-691	61	15	have	have	VERB
biomedich-691	61	16	potential	potential	NOUN
biomedich-691	61	17	as	as	ADP
biomedich-691	61	18	alternatives	alternative	NOUN
biomedich-691	61	19	in	in	ADP
biomedich-691	61	20	the	the	DET
biomedich-691	61	21	treatment	treatment	NOUN
biomedich-691	61	22	of	of	ADP
biomedich-691	61	23	this	this	DET
biomedich-691	61	24	protein	protein	NOUN
biomedich-691	61	25	.	.	PUNCT
biomedich-691	62	1	https://www.rcsb.org/	https://www.rcsb.org/	VERB
biomedich-691	62	2	https://pubchem.ncbi.nlm.nih.gov/	https://pubchem.ncbi.nlm.nih.gov/	PROPN
biomedich-691	62	3	https://biosig.lab.uq.edu.au/pkcsm/prediction	https://biosig.lab.uq.edu.au/pkcsm/prediction	PROPN
biomedich-691	62	4	https://pubchem.ncbi.nlm.nih.gov/	https://pubchem.ncbi.nlm.nih.gov/	PROPN
biomedich-691	63	1	http://www.swissadme.ch/index.php	http://www.swissadme.ch/index.php	INTJ
biomedich-691	63	2	farid	farid	PROPN
biomedich-691	63	3	et	et	PROPN
biomedich-691	63	4	al	al	PROPN
biomedich-691	63	5	.	.	PROPN
biomedich-691	63	6	–	–	PUNCT
biomedich-691	64	1	prediction	prediction	NOUN
biomedich-691	64	2	of	of	ADP
biomedich-691	64	3	artocarpus	artocarpus	PROPN
biomedich-691	64	4	altilis	altili	VERB
biomedich-691	64	5	potential	potential	ADJ
biomedich-691	64	6	as	as	ADP
biomedich-691	64	7	an	an	DET
biomedich-691	64	8	anti	anti	ADJ
biomedich-691	64	9	breast	breast	NOUN
biomedich-691	64	10	cancer	cancer	NOUN
biomedich-691	64	11	…	…	PUNCT
biomedich-691	64	12	201	201	NUM
biomedich-691	64	13	for	for	ADP
biomedich-691	64	14	comparison	comparison	NOUN
biomedich-691	64	15	,	,	PUNCT
biomedich-691	64	16	doxorubicin	doxorubicin	PROPN
biomedich-691	64	17	,	,	PUNCT
biomedich-691	64	18	which	which	PRON
biomedich-691	64	19	has	have	VERB
biomedich-691	64	20	a	a	DET
biomedich-691	64	21	δg	δg	ADJ
biomedich-691	64	22	value	value	NOUN
biomedich-691	64	23	of	of	ADP
biomedich-691	64	24	6.6	6.6	NUM
biomedich-691	64	25	kcal	kcal	NOUN
biomedich-691	64	26	/	/	SYM
biomedich-691	64	27	mol	mol	PROPN
biomedich-691	64	28	,	,	PUNCT
biomedich-691	64	29	serves	serve	VERB
biomedich-691	64	30	as	as	ADP
biomedich-691	64	31	a	a	DET
biomedich-691	64	32	control	control	NOUN
biomedich-691	64	33	in	in	ADP
biomedich-691	64	34	this	this	DET
biomedich-691	64	35	analysis	analysis	NOUN
biomedich-691	64	36	.	.	PUNCT
biomedich-691	65	1	table	table	NOUN
biomedich-691	65	2	1	1	NUM
biomedich-691	65	3	.	.	PUNCT
biomedich-691	66	1	docking	dock	VERB
biomedich-691	66	2	analysis	analysis	NOUN
biomedich-691	66	3	results	result	NOUN
biomedich-691	66	4	.	.	PUNCT
biomedich-691	67	1	compound	compound	NOUN
biomedich-691	67	2	binding	bind	VERB
biomedich-691	67	3	affinity	affinity	NOUN
biomedich-691	67	4	native	native	ADJ
biomedich-691	67	5	ligand	ligand	NOUN
biomedich-691	67	6	-9.5	-9.5	NOUN
biomedich-691	67	7	caffeic	caffeic	VERB
biomedich-691	67	8	acid	acid	NOUN
biomedich-691	67	9	-5.6	-5.6	ADJ
biomedich-691	67	10	chlorogenic	chlorogenic	ADJ
biomedich-691	67	11	acid	acid	NOUN
biomedich-691	67	12	-6.7	-6.7	ADP
biomedich-691	67	13	coumaric	coumaric	ADJ
biomedich-691	67	14	acid	acid	PROPN
biomedich-691	67	15	-5.4	-5.4	PROPN
biomedich-691	67	16	ferulic	ferulic	ADJ
biomedich-691	67	17	acid	acid	NOUN
biomedich-691	67	18	-5.5	-5.5	PUNCT
biomedich-691	67	19	hyperoside	hyperoside	NOUN
biomedich-691	67	20	-6.7	-6.7	ADP
biomedich-691	67	21	quercetin	quercetin	NOUN
biomedich-691	67	22	-7.3	-7.3	PUNCT
biomedich-691	67	23	ellagic	ellagic	ADJ
biomedich-691	67	24	acid	acid	NOUN
biomedich-691	67	25	-8.4	-8.4	NOUN
biomedich-691	67	26	gallic	gallic	NOUN
biomedich-691	67	27	acid	acid	NOUN
biomedich-691	67	28	-5	-5	PUNCT
biomedich-691	68	1	catechin	catechin	PROPN
biomedich-691	68	2	-7.2	-7.2	PROPN
biomedich-691	68	3	epicatechin	epicatechin	NOUN
biomedich-691	68	4	-7.2	-7.2	PUNCT
biomedich-691	68	5	limonene	limonene	NOUN
biomedich-691	68	6	-5	-5	PUNCT
biomedich-691	68	7	γ	γ	NOUN
biomedich-691	68	8	-	-	PUNCT
biomedich-691	68	9	terpinene	terpinene	NOUN
biomedich-691	68	10	-5.1	-5.1	ADJ
biomedich-691	68	11	terpinolene	terpinolene	NOUN
biomedich-691	68	12	-5.2	-5.2	PUNCT
biomedich-691	68	13	doxorubin	doxorubin	ADJ
biomedich-691	68	14	-6.6	-6.6	NOUN
biomedich-691	68	15	visualization	visualization	NOUN
biomedich-691	68	16	of	of	ADP
biomedich-691	68	17	the	the	DET
biomedich-691	68	18	interaction	interaction	NOUN
biomedich-691	68	19	of	of	ADP
biomedich-691	68	20	amino	amino	NOUN
biomedich-691	68	21	acid	acid	NOUN
biomedich-691	68	22	residues	residue	NOUN
biomedich-691	68	23	of	of	ADP
biomedich-691	68	24	natural	natural	ADJ
biomedich-691	68	25	ligands	ligand	NOUN
biomedich-691	68	26	(	(	PUNCT
biomedich-691	68	27	a	a	NOUN
biomedich-691	68	28	)	)	PUNCT
biomedich-691	68	29	,	,	PUNCT
biomedich-691	68	30	doxorubicin	doxorubicin	PROPN
biomedich-691	68	31	(	(	PUNCT
biomedich-691	68	32	b	b	NOUN
biomedich-691	68	33	)	)	PUNCT
biomedich-691	68	34	,	,	PUNCT
biomedich-691	68	35	ellagic	ellagic	ADJ
biomedich-691	68	36	acid	acid	NOUN
biomedich-691	68	37	(	(	PUNCT
biomedich-691	68	38	c	c	NOUN
biomedich-691	68	39	)	)	PUNCT
biomedich-691	68	40	,	,	PUNCT
biomedich-691	68	41	and	and	CCONJ
biomedich-691	68	42	quercetin	quercetin	NOUN
biomedich-691	68	43	(	(	PUNCT
biomedich-691	68	44	d	d	NOUN
biomedich-691	68	45	)	)	PUNCT
biomedich-691	68	46	with	with	ADP
biomedich-691	68	47	egfr	egfr	ADJ
biomedich-691	68	48	protein	protein	NOUN
biomedich-691	68	49	is	be	AUX
biomedich-691	68	50	shown	show	VERB
biomedich-691	68	51	in	in	ADP
biomedich-691	68	52	figure	figure	NOUN
biomedich-691	68	53	1	1	NUM
biomedich-691	68	54	.	.	PUNCT
biomedich-691	69	1	the	the	DET
biomedich-691	69	2	results	result	NOUN
biomedich-691	69	3	of	of	ADP
biomedich-691	69	4	molecular	molecular	ADJ
biomedich-691	69	5	docking	docking	NOUN
biomedich-691	69	6	analysis	analysis	NOUN
biomedich-691	69	7	indicate	indicate	VERB
biomedich-691	69	8	that	that	SCONJ
biomedich-691	69	9	the	the	DET
biomedich-691	69	10	amino	amino	NOUN
biomedich-691	69	11	acid	acid	NOUN
biomedich-691	69	12	residue	residue	NOUN
biomedich-691	69	13	met793	met793	NOUN
biomedich-691	69	14	plays	play	VERB
biomedich-691	69	15	an	an	DET
biomedich-691	69	16	important	important	ADJ
biomedich-691	69	17	role	role	NOUN
biomedich-691	69	18	in	in	ADP
biomedich-691	69	19	the	the	DET
biomedich-691	69	20	formation	formation	NOUN
biomedich-691	69	21	of	of	ADP
biomedich-691	69	22	hydrophobic	hydrophobic	NOUN
biomedich-691	69	23	bonds	bond	NOUN
biomedich-691	69	24	,	,	PUNCT
biomedich-691	69	25	which	which	PRON
biomedich-691	69	26	shows	show	VERB
biomedich-691	69	27	a	a	DET
biomedich-691	69	28	significant	significant	ADJ
biomedich-691	69	29	contribution	contribution	NOUN
biomedich-691	69	30	to	to	ADP
biomedich-691	69	31	the	the	DET
biomedich-691	69	32	stability	stability	NOUN
biomedich-691	69	33	of	of	ADP
biomedich-691	69	34	the	the	DET
biomedich-691	69	35	interaction	interaction	NOUN
biomedich-691	69	36	between	between	ADP
biomedich-691	69	37	the	the	DET
biomedich-691	69	38	ligand	ligand	NOUN
biomedich-691	69	39	and	and	CCONJ
biomedich-691	69	40	the	the	DET
biomedich-691	69	41	target	target	NOUN
biomedich-691	69	42	protein	protein	NOUN
biomedich-691	69	43	.	.	PUNCT
biomedich-691	70	1	these	these	DET
biomedich-691	70	2	findings	finding	NOUN
biomedich-691	70	3	strengthen	strengthen	VERB
biomedich-691	70	4	the	the	DET
biomedich-691	70	5	understanding	understanding	NOUN
biomedich-691	70	6	of	of	ADP
biomedich-691	70	7	the	the	DET
biomedich-691	70	8	mechanism	mechanism	NOUN
biomedich-691	70	9	of	of	ADP
biomedich-691	70	10	ligand	ligand	ADJ
biomedich-691	70	11	interaction	interaction	NOUN
biomedich-691	70	12	with	with	ADP
biomedich-691	70	13	egfr	egfr	NOUN
biomedich-691	70	14	,	,	PUNCT
biomedich-691	70	15	as	as	ADV
biomedich-691	70	16	well	well	ADV
biomedich-691	70	17	as	as	ADP
biomedich-691	70	18	the	the	DET
biomedich-691	70	19	potential	potential	NOUN
biomedich-691	70	20	of	of	ADP
biomedich-691	70	21	natural	natural	ADJ
biomedich-691	70	22	compounds	compound	NOUN
biomedich-691	70	23	in	in	ADP
biomedich-691	70	24	the	the	DET
biomedich-691	70	25	development	development	NOUN
biomedich-691	70	26	of	of	ADP
biomedich-691	70	27	targeted	target	VERB
biomedich-691	70	28	therapies	therapy	NOUN
biomedich-691	70	29	.	.	PUNCT
biomedich-691	71	1	analysis	analysis	NOUN
biomedich-691	71	2	of	of	ADP
biomedich-691	71	3	the	the	DET
biomedich-691	71	4	interaction	interaction	NOUN
biomedich-691	71	5	of	of	ADP
biomedich-691	71	6	amino	amino	NOUN
biomedich-691	71	7	acid	acid	NOUN
biomedich-691	71	8	residues	residue	NOUN
biomedich-691	71	9	formed	form	VERB
biomedich-691	71	10	from	from	ADP
biomedich-691	71	11	the	the	DET
biomedich-691	71	12	native	native	ADJ
biomedich-691	71	13	ligand	ligand	NOUN
biomedich-691	71	14	in	in	ADP
biomedich-691	71	15	figure	figure	NOUN
biomedich-691	71	16	a	a	DET
biomedich-691	71	17	shows	show	NOUN
biomedich-691	71	18	the	the	DET
biomedich-691	71	19	presence	presence	NOUN
biomedich-691	71	20	of	of	ADP
biomedich-691	71	21	hydrogen	hydrogen	NOUN
biomedich-691	71	22	bonds	bond	NOUN
biomedich-691	71	23	between	between	ADP
biomedich-691	71	24	met793	met793	NOUN
biomedich-691	71	25	and	and	CCONJ
biomedich-691	71	26	an	an	DET
biomedich-691	71	27	interaction	interaction	NOUN
biomedich-691	71	28	distance	distance	NOUN
biomedich-691	71	29	of	of	ADP
biomedich-691	71	30	3.20	3.20	NUM
biomedich-691	71	31	å	å	NOUN
biomedich-691	71	32	.	.	PUNCT
biomedich-691	72	1	in	in	ADP
biomedich-691	72	2	addition	addition	NOUN
biomedich-691	72	3	,	,	PUNCT
biomedich-691	72	4	there	there	PRON
biomedich-691	72	5	are	be	VERB
biomedich-691	72	6	five	five	NUM
biomedich-691	72	7	dominant	dominant	ADJ
biomedich-691	72	8	non	non	ADJ
biomedich-691	72	9	-	-	ADJ
biomedich-691	72	10	hydrogen	hydrogen	ADJ
biomedich-691	72	11	bonds	bond	NOUN
biomedich-691	72	12	involving	involve	VERB
biomedich-691	72	13	amino	amino	NOUN
biomedich-691	72	14	acid	acid	NOUN
biomedich-691	72	15	residues	residue	NOUN
biomedich-691	72	16	ala743	ala743	PROPN
biomedich-691	72	17	,	,	PUNCT
biomedich-691	72	18	pro794	pro794	PROPN
biomedich-691	72	19	,	,	PUNCT
biomedich-691	72	20	leu781	leu781	PROPN
biomedich-691	72	21	,	,	PUNCT
biomedich-691	72	22	gly796	gly796	PROPN
biomedich-691	72	23	,	,	PUNCT
biomedich-691	72	24	and	and	CCONJ
biomedich-691	72	25	leu844	leu844	PROPN
biomedich-691	72	26	.	.	PUNCT
biomedich-691	73	1	the	the	DET
biomedich-691	73	2	existence	existence	NOUN
biomedich-691	73	3	of	of	ADP
biomedich-691	73	4	these	these	DET
biomedich-691	73	5	bonds	bond	NOUN
biomedich-691	73	6	indicates	indicate	VERB
biomedich-691	73	7	that	that	SCONJ
biomedich-691	73	8	met793	met793	NOUN
biomedich-691	73	9	plays	play	VERB
biomedich-691	73	10	a	a	DET
biomedich-691	73	11	key	key	ADJ
biomedich-691	73	12	role	role	NOUN
biomedich-691	73	13	in	in	ADP
biomedich-691	73	14	the	the	DET
biomedich-691	73	15	stability	stability	NOUN
biomedich-691	73	16	of	of	ADP
biomedich-691	73	17	ligand	ligand	ADJ
biomedich-691	73	18	interactions	interaction	NOUN
biomedich-691	73	19	with	with	ADP
biomedich-691	73	20	egfr	egfr	ADJ
biomedich-691	73	21	proteins	protein	NOUN
biomedich-691	73	22	,	,	PUNCT
biomedich-691	73	23	as	as	ADV
biomedich-691	73	24	well	well	ADV
biomedich-691	73	25	as	as	ADP
biomedich-691	73	26	contributing	contribute	VERB
biomedich-691	73	27	to	to	ADP
biomedich-691	73	28	the	the	DET
biomedich-691	73	29	efficiency	efficiency	NOUN
biomedich-691	73	30	of	of	ADP
biomedich-691	73	31	ligand	ligand	ADJ
biomedich-691	73	32	binding	bind	VERB
biomedich-691	73	33	(	(	PUNCT
biomedich-691	73	34	radwan	radwan	PROPN
biomedich-691	73	35	et	et	PROPN
biomedich-691	73	36	al	al	PROPN
biomedich-691	73	37	.	.	PROPN
biomedich-691	73	38	,	,	PUNCT
biomedich-691	73	39	2024	2024	NUM
biomedich-691	73	40	)	)	PUNCT
biomedich-691	73	41	.	.	PUNCT
biomedich-691	74	1	doxorubicin	doxorubicin	PROPN
biomedich-691	74	2	,	,	PUNCT
biomedich-691	74	3	as	as	ADP
biomedich-691	74	4	a	a	DET
biomedich-691	74	5	control	control	NOUN
biomedich-691	74	6	drug	drug	NOUN
biomedich-691	74	7	in	in	ADP
biomedich-691	74	8	this	this	DET
biomedich-691	74	9	study	study	NOUN
biomedich-691	74	10	,	,	PUNCT
biomedich-691	74	11	showed	show	VERB
biomedich-691	74	12	that	that	SCONJ
biomedich-691	74	13	the	the	DET
biomedich-691	74	14	amino	amino	NOUN
biomedich-691	74	15	acid	acid	NOUN
biomedich-691	74	16	residue	residue	NOUN
biomedich-691	74	17	pro794	pro794	PROPN
biomedich-691	74	18	also	also	ADV
biomedich-691	74	19	formed	form	VERB
biomedich-691	74	20	hydrogen	hydrogen	NOUN
biomedich-691	74	21	bonds	bond	NOUN
biomedich-691	74	22	with	with	ADP
biomedich-691	74	23	egfr	egfr	NOUN
biomedich-691	74	24	.	.	PUNCT
biomedich-691	75	1	in	in	ADP
biomedich-691	75	2	addition	addition	NOUN
biomedich-691	75	3	,	,	PUNCT
biomedich-691	75	4	there	there	PRON
biomedich-691	75	5	are	be	VERB
biomedich-691	75	6	seven	seven	NUM
biomedich-691	75	7	dominant	dominant	ADJ
biomedich-691	75	8	non	non	ADJ
biomedich-691	75	9	-	-	ADJ
biomedich-691	75	10	hydrogen	hydrogen	ADJ
biomedich-691	75	11	bonds	bond	NOUN
biomedich-691	75	12	involving	involve	VERB
biomedich-691	75	13	residues	residue	NOUN
biomedich-691	75	14	ala743	ala743	PROPN
biomedich-691	75	15	,	,	PUNCT
biomedich-691	75	16	met793	met793	PROPN
biomedich-691	75	17	,	,	PUNCT
biomedich-691	75	18	leu781	leu781	PROPN
biomedich-691	75	19	,	,	PUNCT
biomedich-691	75	20	gly796	gly796	PROPN
biomedich-691	75	21	,	,	PUNCT
biomedich-691	75	22	asp855	asp855	PROPN
biomedich-691	75	23	,	,	PUNCT
biomedich-691	75	24	leu792	leu792	NOUN
biomedich-691	75	25	,	,	PUNCT
biomedich-691	75	26	and	and	CCONJ
biomedich-691	75	27	leu844	leu844	PROPN
biomedich-691	75	28	.	.	PUNCT
biomedich-691	76	1	this	this	PRON
biomedich-691	76	2	indicates	indicate	VERB
biomedich-691	76	3	that	that	SCONJ
biomedich-691	76	4	doxorubicin	doxorubicin	PROPN
biomedich-691	76	5	is	be	AUX
biomedich-691	76	6	able	able	ADJ
biomedich-691	76	7	to	to	PART
biomedich-691	76	8	interact	interact	VERB
biomedich-691	76	9	in	in	ADP
biomedich-691	76	10	a	a	DET
biomedich-691	76	11	complex	complex	NOUN
biomedich-691	76	12	with	with	ADP
biomedich-691	76	13	the	the	DET
biomedich-691	76	14	active	active	ADJ
biomedich-691	76	15	site	site	NOUN
biomedich-691	76	16	of	of	ADP
biomedich-691	76	17	egfr	egfr	NOUN
biomedich-691	76	18	,	,	PUNCT
biomedich-691	76	19	which	which	PRON
biomedich-691	76	20	has	have	VERB
biomedich-691	76	21	the	the	DET
biomedich-691	76	22	potential	potential	NOUN
biomedich-691	76	23	to	to	PART
biomedich-691	76	24	increase	increase	VERB
biomedich-691	76	25	its	its	PRON
biomedich-691	76	26	effectiveness	effectiveness	NOUN
biomedich-691	76	27	as	as	ADP
biomedich-691	76	28	a	a	DET
biomedich-691	76	29	therapeutic	therapeutic	ADJ
biomedich-691	76	30	agent	agent	NOUN
biomedich-691	76	31	(	(	PUNCT
biomedich-691	76	32	ibrahim	ibrahim	PROPN
biomedich-691	76	33	et	et	PROPN
biomedich-691	76	34	al	al	PROPN
biomedich-691	76	35	.	.	PROPN
biomedich-691	76	36	,	,	PUNCT
biomedich-691	76	37	2020	2020	NUM
biomedich-691	76	38	)	)	PUNCT
biomedich-691	76	39	.	.	PUNCT
biomedich-691	77	1	ellagic	ellagic	PROPN
biomedich-691	77	2	acid	acid	NOUN
biomedich-691	77	3	,	,	PUNCT
biomedich-691	77	4	which	which	PRON
biomedich-691	77	5	has	have	VERB
biomedich-691	77	6	the	the	DET
biomedich-691	77	7	lowest	low	ADJ
biomedich-691	77	8	binding	bind	VERB
biomedich-691	77	9	energy	energy	NOUN
biomedich-691	77	10	value	value	NOUN
biomedich-691	77	11	,	,	PUNCT
biomedich-691	77	12	shows	show	VERB
biomedich-691	77	13	three	three	NUM
biomedich-691	77	14	hydrogen	hydrogen	NOUN
biomedich-691	77	15	bonds	bond	NOUN
biomedich-691	77	16	with	with	ADP
biomedich-691	77	17	met793	met793	PROPN
biomedich-691	77	18	,	,	PUNCT
biomedich-691	77	19	met793	met793	NOUN
biomedich-691	77	20	,	,	PUNCT
biomedich-691	77	21	and	and	CCONJ
biomedich-691	77	22	lys745	lys745	ADV
biomedich-691	77	23	as	as	ADP
biomedich-691	77	24	non	non	ADJ
biomedich-691	77	25	-	-	ADJ
biomedich-691	77	26	dominant	dominant	ADJ
biomedich-691	77	27	bonds	bond	NOUN
biomedich-691	77	28	.	.	PUNCT
biomedich-691	78	1	in	in	ADP
biomedich-691	78	2	addition	addition	NOUN
biomedich-691	78	3	,	,	PUNCT
biomedich-691	78	4	four	four	NUM
biomedich-691	78	5	non	non	ADJ
biomedich-691	78	6	-	-	ADJ
biomedich-691	78	7	hydrogen	hydrogen	ADJ
biomedich-691	78	8	bonds	bond	NOUN
biomedich-691	78	9	were	be	AUX
biomedich-691	78	10	found	find	VERB
biomedich-691	78	11	involving	involve	VERB
biomedich-691	78	12	residues	residue	NOUN
biomedich-691	78	13	ala743	ala743	PROPN
biomedich-691	78	14	,	,	PUNCT
biomedich-691	78	15	asp855	asp855	PROPN
biomedich-691	78	16	,	,	PUNCT
biomedich-691	78	17	leu792	leu792	NOUN
biomedich-691	78	18	,	,	PUNCT
biomedich-691	78	19	and	and	CCONJ
biomedich-691	78	20	leu844	leu844	PROPN
biomedich-691	78	21	.	.	PUNCT
biomedich-691	79	1	this	this	PRON
biomedich-691	79	2	shows	show	VERB
biomedich-691	79	3	that	that	SCONJ
biomedich-691	79	4	although	although	SCONJ
biomedich-691	79	5	ellagic	ellagic	ADJ
biomedich-691	79	6	acid	acid	NOUN
biomedich-691	79	7	has	have	VERB
biomedich-691	79	8	a	a	DET
biomedich-691	79	9	low	low	ADJ
biomedich-691	79	10	binding	bind	VERB
biomedich-691	79	11	energy	energy	NOUN
biomedich-691	79	12	,	,	PUNCT
biomedich-691	79	13	the	the	DET
biomedich-691	79	14	interactions	interaction	NOUN
biomedich-691	79	15	formed	form	VERB
biomedich-691	79	16	are	be	AUX
biomedich-691	79	17	still	still	ADV
biomedich-691	79	18	quite	quite	ADV
biomedich-691	79	19	significant	significant	ADJ
biomedich-691	79	20	and	and	CCONJ
biomedich-691	79	21	can	can	AUX
biomedich-691	79	22	contribute	contribute	VERB
biomedich-691	79	23	to	to	ADP
biomedich-691	79	24	the	the	DET
biomedich-691	79	25	anticancer	anticancer	NOUN
biomedich-691	79	26	potential	potential	NOUN
biomedich-691	79	27	of	of	ADP
biomedich-691	79	28	this	this	DET
biomedich-691	79	29	compound	compound	NOUN
biomedich-691	79	30	.	.	PUNCT
biomedich-691	80	1	quercetin	quercetin	NOUN
biomedich-691	80	2	forms	form	NOUN
biomedich-691	80	3	three	three	NUM
biomedich-691	80	4	hydrogen	hydrogen	NOUN
biomedich-691	80	5	amino	amino	NOUN
biomedich-691	80	6	acid	acid	NOUN
biomedich-691	80	7	residue	residue	NOUN
biomedich-691	80	8	interactions	interaction	NOUN
biomedich-691	80	9	,	,	PUNCT
biomedich-691	80	10	namely	namely	ADV
biomedich-691	80	11	with	with	ADP
biomedich-691	80	12	asp855	asp855	PROPN
biomedich-691	80	13	,	,	PUNCT
biomedich-691	80	14	met793	met793	PROPN
biomedich-691	80	15	,	,	PUNCT
biomedich-691	80	16	and	and	CCONJ
biomedich-691	80	17	pro794	pro794	PROPN
biomedich-691	80	18	.	.	PUNCT
biomedich-691	81	1	this	this	DET
biomedich-691	81	2	interaction	interaction	NOUN
biomedich-691	81	3	shows	show	VERB
biomedich-691	81	4	that	that	SCONJ
biomedich-691	81	5	quercetin	quercetin	NOUN
biomedich-691	81	6	also	also	ADV
biomedich-691	81	7	has	have	VERB
biomedich-691	81	8	the	the	DET
biomedich-691	81	9	potential	potential	NOUN
biomedich-691	81	10	to	to	PART
biomedich-691	81	11	bind	bind	VERB
biomedich-691	81	12	the	the	DET
biomedich-691	81	13	egfr	egfr	ADJ
biomedich-691	81	14	protein	protein	NOUN
biomedich-691	81	15	efficiently	efficiently	ADV
biomedich-691	81	16	,	,	PUNCT
biomedich-691	81	17	similar	similar	ADJ
biomedich-691	81	18	to	to	ADP
biomedich-691	81	19	other	other	ADJ
biomedich-691	81	20	compounds	compound	NOUN
biomedich-691	81	21	.	.	PUNCT
biomedich-691	82	1	the	the	DET
biomedich-691	82	2	combination	combination	NOUN
biomedich-691	82	3	of	of	ADP
biomedich-691	82	4	various	various	ADJ
biomedich-691	82	5	amino	amino	NOUN
biomedich-691	82	6	acid	acid	NOUN
biomedich-691	82	7	residue	residue	NOUN
biomedich-691	82	8	interactions	interaction	NOUN
biomedich-691	82	9	in	in	ADP
biomedich-691	82	10	the	the	DET
biomedich-691	82	11	test	test	NOUN
biomedich-691	82	12	ligand	ligand	NOUN
biomedich-691	82	13	shows	show	VERB
biomedich-691	82	14	the	the	DET
biomedich-691	82	15	complexity	complexity	NOUN
biomedich-691	82	16	and	and	CCONJ
biomedich-691	82	17	strength	strength	NOUN
biomedich-691	82	18	of	of	ADP
biomedich-691	82	19	the	the	DET
biomedich-691	82	20	interaction	interaction	NOUN
biomedich-691	82	21	similar	similar	ADJ
biomedich-691	82	22	to	to	ADP
biomedich-691	82	23	the	the	DET
biomedich-691	82	24	control	control	NOUN
biomedich-691	82	25	drug	drug	NOUN
biomedich-691	82	26	,	,	PUNCT
biomedich-691	82	27	so	so	SCONJ
biomedich-691	82	28	that	that	SCONJ
biomedich-691	82	29	in	in	ADP
biomedich-691	82	30	the	the	DET
biomedich-691	82	31	future	future	NOUN
biomedich-691	82	32	it	it	PRON
biomedich-691	82	33	can	can	AUX
biomedich-691	82	34	be	be	AUX
biomedich-691	82	35	further	far	ADV
biomedich-691	82	36	explored	explore	VERB
biomedich-691	82	37	for	for	ADP
biomedich-691	82	38	the	the	DET
biomedich-691	82	39	development	development	NOUN
biomedich-691	82	40	of	of	ADP
biomedich-691	82	41	natural	natural	ADJ
biomedich-691	82	42	compound	compound	NOUN
biomedich-691	82	43	-	-	PUNCT
biomedich-691	82	44	based	base	VERB
biomedich-691	82	45	therapies	therapy	NOUN
biomedich-691	82	46	that	that	PRON
biomedich-691	82	47	are	be	AUX
biomedich-691	82	48	more	more	ADV
biomedich-691	82	49	effective	effective	ADJ
biomedich-691	82	50	and	and	CCONJ
biomedich-691	82	51	have	have	VERB
biomedich-691	82	52	minimal	minimal	ADJ
biomedich-691	82	53	risk	risk	NOUN
biomedich-691	82	54	of	of	ADP
biomedich-691	82	55	toxicity	toxicity	NOUN
biomedich-691	82	56	(	(	PUNCT
biomedich-691	82	57	amelia	amelia	PROPN
biomedich-691	82	58	et	et	PROPN
biomedich-691	82	59	al	al	PROPN
biomedich-691	82	60	.	.	PROPN
biomedich-691	82	61	,	,	PUNCT
biomedich-691	82	62	2022	2022	NUM
biomedich-691	82	63	)	)	PUNCT
biomedich-691	82	64	.	.	PUNCT
biomedich-691	83	1	admet	admet	PROPN
biomedich-691	83	2	analysis	analysis	NOUN
biomedich-691	83	3	all	all	DET
biomedich-691	83	4	compounds	compound	NOUN
biomedich-691	83	5	have	have	VERB
biomedich-691	83	6	molecular	molecular	ADJ
biomedich-691	83	7	weights	weight	NOUN
biomedich-691	83	8	below	below	ADP
biomedich-691	83	9	500	500	NUM
biomedich-691	83	10	.	.	PUNCT
biomedich-691	84	1	log	log	VERB
biomedich-691	84	2	p	p	NOUN
biomedich-691	84	3	(	(	PUNCT
biomedich-691	84	4	<	<	X
biomedich-691	84	5	5	5	NUM
biomedich-691	84	6	)	)	PUNCT
biomedich-691	84	7	all	all	DET
biomedich-691	84	8	compounds	compound	NOUN
biomedich-691	84	9	meet	meet	VERB
biomedich-691	84	10	the	the	DET
biomedich-691	84	11	log	log	NOUN
biomedich-691	84	12	p	p	NOUN
biomedich-691	84	13	criteria	criterion	NOUN
biomedich-691	84	14	,	,	PUNCT
biomedich-691	84	15	indicating	indicate	VERB
biomedich-691	84	16	adequate	adequate	ADJ
biomedich-691	84	17	lipophilicity	lipophilicity	NOUN
biomedich-691	84	18	(	(	PUNCT
biomedich-691	84	19	table	table	NOUN
biomedich-691	84	20	2	2	NUM
biomedich-691	84	21	)	)	PUNCT
biomedich-691	84	22	.	.	PUNCT
biomedich-691	85	1	hydrogen	hydrogen	NOUN
biomedich-691	85	2	bond	bond	NOUN
biomedich-691	85	3	donors	donor	NOUN
biomedich-691	85	4	(	(	PUNCT
biomedich-691	85	5	hbd	hbd	VERB
biomedich-691	85	6	<	<	X
biomedich-691	85	7	5	5	NUM
biomedich-691	85	8	)	)	PUNCT
biomedich-691	85	9	the	the	DET
biomedich-691	85	10	majority	majority	NOUN
biomedich-691	85	11	of	of	ADP
biomedich-691	85	12	compounds	compound	NOUN
biomedich-691	85	13	meet	meet	VERB
biomedich-691	85	14	the	the	DET
biomedich-691	85	15	hbd	hbd	NOUN
biomedich-691	85	16	criteria	criterion	NOUN
biomedich-691	85	17	.	.	PUNCT
biomedich-691	86	1	compounds	compound	NOUN
biomedich-691	86	2	that	that	PRON
biomedich-691	86	3	exceed	exceed	VERB
biomedich-691	86	4	the	the	DET
biomedich-691	86	5	threshold	threshold	NOUN
biomedich-691	86	6	are	be	AUX
biomedich-691	86	7	chlorogenic	chlorogenic	ADJ
biomedich-691	86	8	acid	acid	NOUN
biomedich-691	86	9	(	(	PUNCT
biomedich-691	86	10	6	6	NUM
biomedich-691	86	11	hbd	hbd	NOUN
biomedich-691	86	12	)	)	PUNCT
biomedich-691	86	13	and	and	CCONJ
biomedich-691	86	14	hyperoside	hyperoside	NOUN
biomedich-691	86	15	(	(	PUNCT
biomedich-691	86	16	8	8	NUM
biomedich-691	86	17	hbd	hbd	NOUN
biomedich-691	86	18	)	)	PUNCT
biomedich-691	86	19	,	,	PUNCT
biomedich-691	86	20	which	which	PRON
biomedich-691	86	21	can	can	AUX
biomedich-691	86	22	affect	affect	VERB
biomedich-691	86	23	membrane	membrane	NOUN
biomedich-691	86	24	permeability	permeability	NOUN
biomedich-691	86	25	.	.	PUNCT
biomedich-691	87	1	hydrogen	hydrogen	NOUN
biomedich-691	87	2	bond	bond	NOUN
biomedich-691	87	3	acceptors	acceptor	NOUN
biomedich-691	87	4	(	(	PUNCT
biomedich-691	87	5	hba	hba	X
biomedich-691	87	6	<	<	X
biomedich-691	87	7	10	10	NUM
biomedich-691	87	8	)	)	PUNCT
biomedich-691	87	9	all	all	DET
biomedich-691	87	10	compounds	compound	NOUN
biomedich-691	87	11	meet	meet	VERB
biomedich-691	87	12	the	the	DET
biomedich-691	87	13	hba	hba	NOUN
biomedich-691	87	14	criteria	criterion	NOUN
biomedich-691	87	15	except	except	SCONJ
biomedich-691	87	16	hyperoside	hyperoside	NOUN
biomedich-691	87	17	,	,	PUNCT
biomedich-691	87	18	which	which	PRON
biomedich-691	87	19	has	have	VERB
biomedich-691	87	20	an	an	DET
biomedich-691	87	21	hba	hba	NOUN
biomedich-691	87	22	value	value	NOUN
biomedich-691	87	23	of	of	ADP
biomedich-691	87	24	12	12	NUM
biomedich-691	87	25	,	,	PUNCT
biomedich-691	87	26	above	above	ADP
biomedich-691	87	27	the	the	DET
biomedich-691	87	28	threshold	threshold	NOUN
biomedich-691	87	29	.	.	PUNCT
biomedich-691	88	1	not	not	PART
biomedich-691	88	2	all	all	DET
biomedich-691	88	3	compounds	compound	NOUN
biomedich-691	88	4	show	show	VERB
biomedich-691	88	5	hepatotoxic	hepatotoxic	NOUN
biomedich-691	88	6	properties	property	NOUN
biomedich-691	88	7	and	and	CCONJ
biomedich-691	88	8	therefore	therefore	ADV
biomedich-691	88	9	do	do	AUX
biomedich-691	88	10	not	not	PART
biomedich-691	88	11	pose	pose	VERB
biomedich-691	88	12	a	a	DET
biomedich-691	88	13	risk	risk	NOUN
biomedich-691	88	14	for	for	ADP
biomedich-691	88	15	clinical	clinical	ADJ
biomedich-691	88	16	application	application	NOUN
biomedich-691	88	17	.	.	PUNCT
biomedich-691	89	1	all	all	DET
biomedich-691	89	2	compounds	compound	NOUN
biomedich-691	89	3	have	have	VERB
biomedich-691	89	4	no	no	DET
biomedich-691	89	5	mutagenic	mutagenic	ADJ
biomedich-691	89	6	potential	potential	NOUN
biomedich-691	89	7	based	base	VERB
biomedich-691	89	8	on	on	ADP
biomedich-691	89	9	the	the	DET
biomedich-691	89	10	ames	ames	PROPN
biomedich-691	89	11	test	test	NOUN
biomedich-691	89	12	(	(	PUNCT
biomedich-691	89	13	guan	guan	PROPN
biomedich-691	89	14	et	et	PROPN
biomedich-691	89	15	al	al	PROPN
biomedich-691	89	16	.	.	PROPN
biomedich-691	89	17	,	,	PUNCT
biomedich-691	89	18	2018	2018	NUM
biomedich-691	89	19	)	)	PUNCT
biomedich-691	89	20	.	.	PUNCT
biomedich-691	90	1	202	202	NUM
biomedich-691	90	2	biology	biology	NOUN
biomedich-691	90	3	,	,	PUNCT
biomedich-691	90	4	medicine	medicine	NOUN
biomedich-691	90	5	,	,	PUNCT
biomedich-691	90	6	&	&	CCONJ
biomedich-691	90	7	natural	natural	ADJ
biomedich-691	90	8	product	product	NOUN
biomedich-691	90	9	chemistry	chemistry	NOUN
biomedich-691	90	10	14	14	NUM
biomedich-691	90	11	(	(	PUNCT
biomedich-691	90	12	1	1	NUM
biomedich-691	90	13	)	)	PUNCT
biomedich-691	90	14	,	,	PUNCT
biomedich-691	90	15	2025	2025	NUM
biomedich-691	90	16	:	:	PUNCT
biomedich-691	90	17	199	199	NUM
biomedich-691	90	18	-	-	SYM
biomedich-691	90	19	204	204	NUM
biomedich-691	90	20	figure	figure	NOUN
biomedich-691	90	21	1	1	NUM
biomedich-691	90	22	.	.	PUNCT
biomedich-691	90	23	visualization	visualization	NOUN
biomedich-691	90	24	of	of	ADP
biomedich-691	90	25	amino	amino	NOUN
biomedich-691	90	26	acid	acid	NOUN
biomedich-691	90	27	interactions	interaction	NOUN
biomedich-691	90	28	between	between	ADP
biomedich-691	90	29	proteins	protein	NOUN
biomedich-691	90	30	and	and	CCONJ
biomedich-691	90	31	ligands	ligand	NOUN
biomedich-691	90	32	(	(	PUNCT
biomedich-691	90	33	a.	a.	NOUN
biomedich-691	90	34	native	native	PROPN
biomedich-691	90	35	ligand	ligand	PROPN
biomedich-691	90	36	,	,	PUNCT
biomedich-691	90	37	b.	b.	PROPN
biomedich-691	90	38	doxorubicin	doxorubicin	PROPN
biomedich-691	90	39	,	,	PUNCT
biomedich-691	90	40	c.	c.	PROPN
biomedich-691	90	41	ellagic	ellagic	PROPN
biomedich-691	90	42	acid	acid	PROPN
biomedich-691	90	43	,	,	PUNCT
biomedich-691	90	44	d.	d.	NOUN
biomedich-691	90	45	quercetin	quercetin	NOUN
biomedich-691	90	46	)	)	PUNCT
biomedich-691	90	47	.	.	PUNCT
biomedich-691	91	1	table	table	NOUN
biomedich-691	91	2	2	2	NUM
biomedich-691	91	3	.	.	PUNCT
biomedich-691	91	4	physicochemical	physicochemical	ADJ
biomedich-691	91	5	analysis	analysis	NOUN
biomedich-691	91	6	and	and	CCONJ
biomedich-691	91	7	toxicity	toxicity	NOUN
biomedich-691	91	8	.	.	PUNCT
biomedich-691	92	1	compound	compound	NOUN
biomedich-691	92	2	mw	mw	PROPN
biomedich-691	92	3	(	(	PUNCT
biomedich-691	92	4	<	<	NOUN
biomedich-691	92	5	500	500	NUM
biomedich-691	92	6	)	)	PUNCT
biomedich-691	92	7	log	log	NOUN
biomedich-691	92	8	p	p	NOUN
biomedich-691	92	9	(	(	PUNCT
biomedich-691	92	10	<	<	NOUN
biomedich-691	92	11	5	5	NUM
biomedich-691	92	12	)	)	PUNCT
biomedich-691	92	13	hbd	hbd	NOUN
biomedich-691	92	14	(	(	PUNCT
biomedich-691	92	15	<	<	NOUN
biomedich-691	92	16	5	5	NUM
biomedich-691	92	17	)	)	PUNCT
biomedich-691	92	18	hba	hba	NOUN
biomedich-691	92	19	(	(	PUNCT
biomedich-691	92	20	<	<	NOUN
biomedich-691	92	21	10	10	NUM
biomedich-691	92	22	)	)	PUNCT
biomedich-691	92	23	hepatotoxicity	hepatotoxicity	NOUN
biomedich-691	92	24	ames	ame	NOUN
biomedich-691	92	25	mutagenesis	mutagenesis	NOUN
biomedich-691	92	26	caffeic	caffeic	VERB
biomedich-691	92	27	acid	acid	PROPN
biomedich-691	92	28	180.16	180.16	NUM
biomedich-691	92	29	1.09	1.09	NUM
biomedich-691	92	30	3	3	NUM
biomedich-691	92	31	4	4	NUM
biomedich-691	92	32	no	no	PRON
biomedich-691	92	33	no	no	DET
biomedich-691	92	34	chlorogenic	chlorogenic	ADJ
biomedich-691	92	35	acid	acid	NOUN
biomedich-691	92	36	354.31	354.31	NUM
biomedich-691	92	37	0.75	0.75	NUM
biomedich-691	92	38	6	6	NUM
biomedich-691	92	39	9	9	NUM
biomedich-691	92	40	no	no	DET
biomedich-691	92	41	no	no	DET
biomedich-691	92	42	coumaric	coumaric	ADJ
biomedich-691	92	43	acid	acid	NOUN
biomedich-691	92	44	164.16	164.16	NUM
biomedich-691	92	45	1.38	1.38	NUM
biomedich-691	92	46	2	2	NUM
biomedich-691	92	47	3	3	NUM
biomedich-691	92	48	no	no	DET
biomedich-691	92	49	no	no	DET
biomedich-691	92	50	ferulic	ferulic	ADJ
biomedich-691	92	51	acid	acid	NOUN
biomedich-691	92	52	194.18	194.18	NUM
biomedich-691	92	53	1.39	1.39	NUM
biomedich-691	92	54	2	2	NUM
biomedich-691	92	55	4	4	NUM
biomedich-691	92	56	no	no	INTJ
biomedich-691	92	57	no	no	DET
biomedich-691	92	58	hyperoside	hyperoside	NOUN
biomedich-691	92	59	464.38	464.38	NUM
biomedich-691	92	60	0.54	0.54	NUM
biomedich-691	92	61	8	8	NUM
biomedich-691	92	62	12	12	NUM
biomedich-691	92	63	no	no	INTJ
biomedich-691	92	64	no	no	DET
biomedich-691	92	65	quercetin	quercetin	NOUN
biomedich-691	92	66	302.24	302.24	NUM
biomedich-691	92	67	1.99	1.99	NUM
biomedich-691	92	68	5	5	NUM
biomedich-691	92	69	7	7	NUM
biomedich-691	92	70	no	no	INTJ
biomedich-691	92	71	no	no	DET
biomedich-691	92	72	ellagic	ellagic	ADJ
biomedich-691	92	73	acid	acid	NOUN
biomedich-691	92	74	302.19	302.19	NUM
biomedich-691	92	75	1.31	1.31	NUM
biomedich-691	92	76	4	4	NUM
biomedich-691	92	77	8	8	NUM
biomedich-691	92	78	no	no	PRON
biomedich-691	92	79	no	no	DET
biomedich-691	92	80	gallic	gallic	NOUN
biomedich-691	92	81	acid	acid	NOUN
biomedich-691	92	82	170.12	170.12	NUM
biomedich-691	92	83	0.50	0.50	NUM
biomedich-691	92	84	4	4	NUM
biomedich-691	92	85	5	5	NUM
biomedich-691	92	86	no	no	INTJ
biomedich-691	93	1	no	no	DET
biomedich-691	93	2	catechin	catechin	NOUN
biomedich-691	93	3	290.27	290.27	NUM
biomedich-691	93	4	1.22	1.22	NUM
biomedich-691	93	5	5	5	NUM
biomedich-691	93	6	6	6	NUM
biomedich-691	93	7	no	no	INTJ
biomedich-691	93	8	no	no	DET
biomedich-691	93	9	epicatechin	epicatechin	NOUN
biomedich-691	93	10	290.27	290.27	NUM
biomedich-691	93	11	1.22	1.22	NUM
biomedich-691	93	12	5	5	NUM
biomedich-691	93	13	6	6	NUM
biomedich-691	93	14	no	no	INTJ
biomedich-691	93	15	no	no	DET
biomedich-691	93	16	limonene	limonene	NOUN
biomedich-691	93	17	136.23	136.23	NUM
biomedich-691	93	18	3.31	3.31	NUM
biomedich-691	93	19	0	0	NUM
biomedich-691	93	20	0	0	NUM
biomedich-691	94	1	no	no	DET
biomedich-691	94	2	no	no	DET
biomedich-691	94	3	γ	γ	NOUN
biomedich-691	94	4	-	-	PUNCT
biomedich-691	94	5	terpinene	terpinene	NOUN
biomedich-691	94	6	136.23	136.23	NUM
biomedich-691	94	7	3.31	3.31	NUM
biomedich-691	94	8	0	0	NUM
biomedich-691	94	9	0	0	NUM
biomedich-691	95	1	no	no	DET
biomedich-691	95	2	no	no	DET
biomedich-691	95	3	terpinolene	terpinolene	NOUN
biomedich-691	95	4	136.23	136.23	NUM
biomedich-691	95	5	3.45	3.45	NUM
biomedich-691	95	6	0	0	NUM
biomedich-691	95	7	0	0	NUM
biomedich-691	96	1	no	no	INTJ
biomedich-691	96	2	no	no	INTJ
biomedich-691	96	3	farid	farid	NOUN
biomedich-691	96	4	et	et	PROPN
biomedich-691	96	5	al	al	PROPN
biomedich-691	96	6	.	.	PROPN
biomedich-691	96	7	–	–	PUNCT
biomedich-691	96	8	prediction	prediction	NOUN
biomedich-691	96	9	of	of	ADP
biomedich-691	96	10	artocarpus	artocarpus	PROPN
biomedich-691	96	11	altilis	altili	VERB
biomedich-691	96	12	potential	potential	ADJ
biomedich-691	96	13	as	as	ADP
biomedich-691	96	14	an	an	DET
biomedich-691	96	15	anti	anti	ADJ
biomedich-691	96	16	breast	breast	NOUN
biomedich-691	96	17	cancer	cancer	NOUN
biomedich-691	96	18	…	…	PUNCT
biomedich-691	96	19	203	203	NUM
biomedich-691	96	20	conclusion	conclusion	NOUN
biomedich-691	96	21	ellagic	ellagic	PROPN
biomedich-691	96	22	acid	acid	NOUN
biomedich-691	96	23	has	have	VERB
biomedich-691	96	24	the	the	DET
biomedich-691	96	25	highest	high	ADJ
biomedich-691	96	26	binding	bind	VERB
biomedich-691	96	27	affinity	affinity	NOUN
biomedich-691	96	28	(	(	PUNCT
biomedich-691	96	29	-8.4	-8.4	X
biomedich-691	96	30	kcal	kcal	NOUN
biomedich-691	96	31	/	/	SYM
biomedich-691	96	32	mol	mol	NOUN
biomedich-691	96	33	)	)	PUNCT
biomedich-691	96	34	,	,	PUNCT
biomedich-691	96	35	followed	follow	VERB
biomedich-691	96	36	by	by	ADP
biomedich-691	96	37	quercetin	quercetin	NOUN
biomedich-691	96	38	(	(	PUNCT
biomedich-691	96	39	-7.3	-7.3	ADV
biomedich-691	96	40	kcal	kcal	PROPN
biomedich-691	96	41	/	/	SYM
biomedich-691	96	42	mol	mol	NOUN
biomedich-691	96	43	)	)	PUNCT
biomedich-691	96	44	,	,	PUNCT
biomedich-691	96	45	catechin	catechin	NOUN
biomedich-691	96	46	,	,	PUNCT
biomedich-691	96	47	and	and	CCONJ
biomedich-691	96	48	epicatechin	epicatechin	PROPN
biomedich-691	96	49	(	(	PUNCT
biomedich-691	96	50	-7.2	-7.2	PROPN
biomedich-691	96	51	kcal	kcal	PROPN
biomedich-691	96	52	/	/	SYM
biomedich-691	96	53	mol	mol	NOUN
biomedich-691	96	54	)	)	PUNCT
biomedich-691	96	55	.	.	PUNCT
biomedich-691	97	1	interaction	interaction	NOUN
biomedich-691	97	2	of	of	ADP
biomedich-691	97	3	amino	amino	NOUN
biomedich-691	97	4	acid	acid	NOUN
biomedich-691	97	5	residues	residue	NOUN
biomedich-691	97	6	,	,	PUNCT
biomedich-691	97	7	such	such	ADJ
biomedich-691	97	8	as	as	ADP
biomedich-691	97	9	met793	met793	NOUN
biomedich-691	97	10	,	,	PUNCT
biomedich-691	97	11	provides	provide	VERB
biomedich-691	97	12	stability	stability	NOUN
biomedich-691	97	13	in	in	ADP
biomedich-691	97	14	ligand	ligand	ADJ
biomedich-691	97	15	binding	binding	NOUN
biomedich-691	97	16	.	.	PUNCT
biomedich-691	98	1	pharmacokinetically	pharmacokinetically	ADV
biomedich-691	98	2	,	,	PUNCT
biomedich-691	98	3	compounds	compound	VERB
biomedich-691	98	4	such	such	ADJ
biomedich-691	98	5	as	as	ADP
biomedich-691	98	6	ellagic	ellagic	ADJ
biomedich-691	98	7	acid	acid	NOUN
biomedich-691	98	8	and	and	CCONJ
biomedich-691	98	9	quercetin	quercetin	NOUN
biomedich-691	98	10	show	show	NOUN
biomedich-691	98	11	good	good	ADJ
biomedich-691	98	12	profiles	profile	NOUN
biomedich-691	98	13	according	accord	VERB
biomedich-691	98	14	to	to	ADP
biomedich-691	98	15	lipinski	lipinski	PROPN
biomedich-691	98	16	's	's	PART
biomedich-691	98	17	rule	rule	NOUN
biomedich-691	98	18	,	,	PUNCT
biomedich-691	98	19	with	with	ADP
biomedich-691	98	20	no	no	DET
biomedich-691	98	21	indication	indication	NOUN
biomedich-691	98	22	of	of	ADP
biomedich-691	98	23	hepatotoxicity	hepatotoxicity	NOUN
biomedich-691	98	24	or	or	CCONJ
biomedich-691	98	25	mutagenesis	mutagenesis	NOUN
biomedich-691	98	26	.	.	PUNCT
biomedich-691	99	1	acknowledgement	acknowledgement	NOUN
biomedich-691	99	2	:	:	PUNCT
biomedich-691	99	3	the	the	DET
biomedich-691	99	4	authors	author	NOUN
biomedich-691	99	5	declare	declare	VERB
biomedich-691	99	6	that	that	SCONJ
biomedich-691	99	7	there	there	PRON
biomedich-691	99	8	is	be	VERB
biomedich-691	99	9	no	no	DET
biomedich-691	99	10	conflict	conflict	NOUN
biomedich-691	99	11	of	of	ADP
biomedich-691	99	12	interest	interest	NOUN
biomedich-691	99	13	in	in	ADP
biomedich-691	99	14	this	this	DET
biomedich-691	99	15	research	research	NOUN
biomedich-691	99	16	and	and	CCONJ
biomedich-691	99	17	this	this	DET
biomedich-691	99	18	research	research	NOUN
biomedich-691	99	19	did	do	AUX
biomedich-691	99	20	not	not	PART
biomedich-691	99	21	receive	receive	VERB
biomedich-691	99	22	funding	funding	NOUN
biomedich-691	99	23	from	from	ADP
biomedich-691	99	24	any	any	DET
biomedich-691	99	25	source	source	NOUN
biomedich-691	99	26	.	.	PUNCT
biomedich-691	100	1	all	all	DET
biomedich-691	100	2	relevant	relevant	ADJ
biomedich-691	100	3	information	information	NOUN
biomedich-691	100	4	has	have	AUX
biomedich-691	100	5	been	be	AUX
biomedich-691	100	6	provided	provide	VERB
biomedich-691	100	7	in	in	ADP
biomedich-691	100	8	this	this	DET
biomedich-691	100	9	article	article	NOUN
biomedich-691	100	10	.	.	PUNCT
biomedich-691	101	1	competing	compete	VERB
biomedich-691	101	2	interests	interest	NOUN
biomedich-691	101	3	:	:	PUNCT
biomedich-691	101	4	the	the	DET
biomedich-691	101	5	authors	author	NOUN
biomedich-691	101	6	declare	declare	VERB
biomedich-691	101	7	that	that	SCONJ
biomedich-691	101	8	there	there	PRON
biomedich-691	101	9	are	be	VERB
biomedich-691	101	10	no	no	DET
biomedich-691	101	11	competing	compete	VERB
biomedich-691	101	12	interests	interest	NOUN
biomedich-691	101	13	.	.	PUNCT
biomedich-691	102	1	references	reference	NOUN
biomedich-691	102	2	acharya	acharya	PROPN
biomedich-691	102	3	,	,	PUNCT
biomedich-691	102	4	r.	r.	PROPN
biomedich-691	102	5	,	,	PUNCT
biomedich-691	102	6	chacko	chacko	NOUN
biomedich-691	102	7	,	,	PUNCT
biomedich-691	102	8	s.	s.	PROPN
biomedich-691	102	9	,	,	PUNCT
biomedich-691	102	10	bose	bose	PROPN
biomedich-691	102	11	,	,	PUNCT
biomedich-691	102	12	p.	p.	NOUN
biomedich-691	102	13	,	,	PUNCT
biomedich-691	102	14	lapenna	lapenna	NOUN
biomedich-691	102	15	,	,	PUNCT
biomedich-691	102	16	a.	a.	NOUN
biomedich-691	102	17	,	,	PUNCT
biomedich-691	102	18	&	&	CCONJ
biomedich-691	102	19	pattanayak	pattanayak	PROPN
biomedich-691	102	20	,	,	PUNCT
biomedich-691	102	21	s.	s.	PROPN
biomedich-691	102	22	p.	p.	PROPN
biomedich-691	102	23	(	(	PUNCT
biomedich-691	102	24	2019	2019	NUM
biomedich-691	102	25	)	)	PUNCT
biomedich-691	102	26	.	.	PUNCT
biomedich-691	103	1	structure	structure	NOUN
biomedich-691	103	2	based	base	VERB
biomedich-691	103	3	multitargeted	multitargete	VERB
biomedich-691	103	4	molecular	molecular	ADJ
biomedich-691	103	5	docking	docking	NOUN
biomedich-691	103	6	analysis	analysis	NOUN
biomedich-691	103	7	of	of	ADP
biomedich-691	103	8	selected	select	VERB
biomedich-691	103	9	furanocoumarins	furanocoumarin	NOUN
biomedich-691	103	10	against	against	ADP
biomedich-691	103	11	breast	breast	NOUN
biomedich-691	103	12	cancer	cancer	NOUN
biomedich-691	103	13	.	.	PUNCT
biomedich-691	104	1	scientific	scientific	ADJ
biomedich-691	104	2	reports	report	NOUN
biomedich-691	104	3	,	,	PUNCT
biomedich-691	104	4	9(1	9(1	NUM
biomedich-691	104	5	)	)	PUNCT
biomedich-691	104	6	.	.	PUNCT
biomedich-691	105	1	https://doi.org/10.1038/s41598-01952162-0	https://doi.org/10.1038/s41598-01952162-0	PROPN
biomedich-691	105	2	afladhanti	afladhanti	PROPN
biomedich-691	105	3	,	,	PUNCT
biomedich-691	105	4	m.	m.	PROPN
biomedich-691	105	5	p.	p.	PROPN
biomedich-691	105	6	,	,	PUNCT
biomedich-691	105	7	ali	ali	PROPN
biomedich-691	105	8	hamzah	hamzah	PROPN
biomedich-691	105	9	,	,	PUNCT
biomedich-691	105	10	h.	h.	PROPN
biomedich-691	105	11	,	,	PUNCT
biomedich-691	105	12	romadhan	romadhan	PROPN
biomedich-691	105	13	,	,	PUNCT
biomedich-691	105	14	m.	m.	NOUN
biomedich-691	105	15	d.	d.	PROPN
biomedich-691	105	16	,	,	PUNCT
biomedich-691	105	17	putri	putri	PROPN
biomedich-691	105	18	,	,	PUNCT
biomedich-691	105	19	s.	s.	PROPN
biomedich-691	105	20	n.	n.	PROPN
biomedich-691	105	21	,	,	PUNCT
biomedich-691	105	22	&	&	CCONJ
biomedich-691	105	23	angelica	angelica	PROPN
biomedich-691	105	24	,	,	PUNCT
biomedich-691	105	25	e.	e.	PROPN
biomedich-691	105	26	c.	c.	PROPN
biomedich-691	105	27	(	(	PUNCT
biomedich-691	105	28	2023	2023	NUM
biomedich-691	105	29	)	)	PUNCT
biomedich-691	105	30	.	.	PUNCT
biomedich-691	106	1	etlingera	etlingera	PROPN
biomedich-691	106	2	elatior	elatior	PROPN
biomedich-691	106	3	compounds	compound	NOUN
biomedich-691	106	4	as	as	ADP
biomedich-691	106	5	anticancer	anticancer	NOUN
biomedich-691	106	6	agents	agent	NOUN
biomedich-691	106	7	of	of	ADP
biomedich-691	106	8	breast	breast	NOUN
biomedich-691	106	9	cancer	cancer	NOUN
biomedich-691	106	10	through	through	ADP
biomedich-691	106	11	inhibition	inhibition	NOUN
biomedich-691	106	12	of	of	ADP
biomedich-691	106	13	progesterone	progesterone	NOUN
biomedich-691	106	14	receptor	receptor	NOUN
biomedich-691	106	15	:	:	PUNCT
biomedich-691	106	16	an	an	PRON
biomedich-691	106	17	in	in	ADP
biomedich-691	106	18	silico	silico	NOUN
biomedich-691	106	19	study	study	NOUN
biomedich-691	106	20	.	.	PUNCT
biomedich-691	107	1	indonesian	indonesian	ADJ
biomedich-691	107	2	journal	journal	PROPN
biomedich-691	107	3	of	of	ADP
biomedich-691	107	4	cancer	cancer	NOUN
biomedich-691	107	5	chemoprevention	chemoprevention	PROPN
biomedich-691	107	6	,	,	PUNCT
biomedich-691	107	7	14(2	14(2	NUM
biomedich-691	107	8	)	)	PUNCT
biomedich-691	107	9	,	,	PUNCT
biomedich-691	107	10	94–104	94–104	PROPN
biomedich-691	107	11	.	.	PUNCT
biomedich-691	108	1	http://www.swissadme.ch/	http://www.swissadme.ch/	VERB
biomedich-691	108	2	agu	agu	NOUN
biomedich-691	108	3	,	,	PUNCT
biomedich-691	108	4	p.	p.	PROPN
biomedich-691	108	5	c.	c.	PROPN
biomedich-691	108	6	,	,	PUNCT
biomedich-691	108	7	afiukwa	afiukwa	PROPN
biomedich-691	108	8	,	,	PUNCT
biomedich-691	108	9	c.	c.	PROPN
biomedich-691	108	10	a.	a.	PROPN
biomedich-691	108	11	,	,	PUNCT
biomedich-691	108	12	orji	orji	PROPN
biomedich-691	108	13	,	,	PUNCT
biomedich-691	108	14	o.	o.	PROPN
biomedich-691	108	15	u.	u.	PROPN
biomedich-691	108	16	,	,	PUNCT
biomedich-691	108	17	ezeh	ezeh	PROPN
biomedich-691	108	18	,	,	PUNCT
biomedich-691	108	19	e.	e.	PROPN
biomedich-691	108	20	m.	m.	PROPN
biomedich-691	108	21	,	,	PUNCT
biomedich-691	108	22	ofoke	ofoke	PROPN
biomedich-691	108	23	,	,	PUNCT
biomedich-691	108	24	i.	i.	PROPN
biomedich-691	108	25	h.	h.	PROPN
biomedich-691	108	26	,	,	PUNCT
biomedich-691	108	27	ogbu	ogbu	ADV
biomedich-691	108	28	,	,	PUNCT
biomedich-691	108	29	c.	c.	PROPN
biomedich-691	108	30	o.	o.	PROPN
biomedich-691	108	31	,	,	PUNCT
biomedich-691	108	32	ugwuja	ugwuja	PROPN
biomedich-691	108	33	,	,	PUNCT
biomedich-691	108	34	e.	e.	PROPN
biomedich-691	108	35	i.	i.	PROPN
biomedich-691	108	36	,	,	PUNCT
biomedich-691	108	37	&	&	CCONJ
biomedich-691	108	38	aja	aja	PROPN
biomedich-691	108	39	,	,	PUNCT
biomedich-691	108	40	p.	p.	NOUN
biomedich-691	108	41	m.	m.	NOUN
biomedich-691	108	42	(	(	PUNCT
biomedich-691	108	43	2023	2023	NUM
biomedich-691	108	44	)	)	PUNCT
biomedich-691	108	45	.	.	PUNCT
biomedich-691	109	1	molecular	molecular	ADJ
biomedich-691	109	2	docking	docking	NOUN
biomedich-691	109	3	as	as	ADP
biomedich-691	109	4	a	a	DET
biomedich-691	109	5	tool	tool	NOUN
biomedich-691	109	6	for	for	ADP
biomedich-691	109	7	the	the	DET
biomedich-691	109	8	discovery	discovery	NOUN
biomedich-691	109	9	of	of	ADP
biomedich-691	109	10	molecular	molecular	ADJ
biomedich-691	109	11	targets	target	NOUN
biomedich-691	109	12	of	of	ADP
biomedich-691	109	13	nutraceuticals	nutraceutical	NOUN
biomedich-691	109	14	in	in	ADP
biomedich-691	109	15	diseases	disease	NOUN
biomedich-691	109	16	management	management	NOUN
biomedich-691	109	17	.	.	PUNCT
biomedich-691	110	1	scientific	scientific	ADJ
biomedich-691	110	2	reports	report	NOUN
biomedich-691	110	3	,	,	PUNCT
biomedich-691	110	4	13(1	13(1	NUM
biomedich-691	110	5	)	)	PUNCT
biomedich-691	110	6	.	.	PUNCT
biomedich-691	111	1	https://doi.org/10.1038/s41598-023-40160-2	https://doi.org/10.1038/s41598-023-40160-2	PROPN
biomedich-691	112	1	amelia	amelia	PROPN
biomedich-691	112	2	,	,	PUNCT
biomedich-691	112	3	t.	t.	PROPN
biomedich-691	112	4	,	,	PUNCT
biomedich-691	112	5	kartasasmita	kartasasmita	PROPN
biomedich-691	112	6	,	,	PUNCT
biomedich-691	112	7	r.	r.	PROPN
biomedich-691	112	8	e.	e.	PROPN
biomedich-691	112	9	,	,	PUNCT
biomedich-691	112	10	ohwada	ohwada	PROPN
biomedich-691	112	11	,	,	PUNCT
biomedich-691	112	12	t.	t.	PROPN
biomedich-691	112	13	,	,	PUNCT
biomedich-691	112	14	&	&	CCONJ
biomedich-691	112	15	tjahjono	tjahjono	PROPN
biomedich-691	112	16	,	,	PUNCT
biomedich-691	112	17	d.	d.	PROPN
biomedich-691	112	18	h.	h.	PROPN
biomedich-691	112	19	(	(	PUNCT
biomedich-691	112	20	2022	2022	NUM
biomedich-691	112	21	)	)	PUNCT
biomedich-691	112	22	.	.	PUNCT
biomedich-691	113	1	structural	structural	ADJ
biomedich-691	113	2	insight	insight	NOUN
biomedich-691	113	3	and	and	CCONJ
biomedich-691	113	4	development	development	NOUN
biomedich-691	113	5	of	of	ADP
biomedich-691	113	6	egfr	egfr	ADJ
biomedich-691	113	7	tyrosine	tyrosine	PROPN
biomedich-691	113	8	kinase	kinase	PROPN
biomedich-691	113	9	inhibitors	inhibitor	NOUN
biomedich-691	113	10	.	.	PUNCT
biomedich-691	114	1	in	in	ADP
biomedich-691	114	2	molecules	molecule	NOUN
biomedich-691	114	3	(	(	PUNCT
biomedich-691	114	4	vol	vol	NOUN
biomedich-691	114	5	.	.	NOUN
biomedich-691	114	6	27	27	NUM
biomedich-691	114	7	,	,	PUNCT
biomedich-691	114	8	issue	issue	NOUN
biomedich-691	114	9	3	3	NUM
biomedich-691	114	10	)	)	PUNCT
biomedich-691	114	11	.	.	PUNCT
biomedich-691	115	1	mdpi	mdpi	PROPN
biomedich-691	115	2	.	.	PUNCT
biomedich-691	115	3	https://doi.org/10.3390/molecules27030819	https://doi.org/10.3390/molecules27030819	NOUN
biomedich-691	115	4	aswathy	aswathy	ADJ
biomedich-691	115	5	,	,	PUNCT
biomedich-691	115	6	m.	m.	NOUN
biomedich-691	115	7	,	,	PUNCT
biomedich-691	115	8	parama	parama	PROPN
biomedich-691	115	9	,	,	PUNCT
biomedich-691	115	10	d.	d.	PROPN
biomedich-691	115	11	,	,	PUNCT
biomedich-691	115	12	hegde	hegde	PROPN
biomedich-691	115	13	,	,	PUNCT
biomedich-691	115	14	m.	m.	NOUN
biomedich-691	115	15	,	,	PUNCT
biomedich-691	115	16	dr	dr	PROPN
biomedich-691	115	17	,	,	PUNCT
biomedich-691	115	18	s.	s.	PROPN
biomedich-691	115	19	,	,	PUNCT
biomedich-691	115	20	lankalapalli	lankalapalli	PROPN
biomedich-691	115	21	,	,	PUNCT
biomedich-691	115	22	r.	r.	PROPN
biomedich-691	115	23	s.	s.	PROPN
biomedich-691	115	24	,	,	PUNCT
biomedich-691	115	25	radhakrishnan	radhakrishnan	PROPN
biomedich-691	115	26	,	,	PUNCT
biomedich-691	115	27	k.	k.	PROPN
biomedich-691	116	1	v.	v.	PROPN
biomedich-691	116	2	,	,	PUNCT
biomedich-691	116	3	&	&	CCONJ
biomedich-691	116	4	kunnumakkara	kunnumakkara	PROPN
biomedich-691	116	5	,	,	PUNCT
biomedich-691	116	6	a.	a.	PROPN
biomedich-691	116	7	b.	b.	PROPN
biomedich-691	116	8	(	(	PUNCT
biomedich-691	116	9	2024	2024	NUM
biomedich-691	116	10	)	)	PUNCT
biomedich-691	116	11	.	.	PUNCT
biomedich-691	117	1	natural	natural	ADJ
biomedich-691	117	2	prenylflavones	prenylflavone	NOUN
biomedich-691	117	3	from	from	ADP
biomedich-691	117	4	the	the	DET
biomedich-691	117	5	stem	stem	NOUN
biomedich-691	117	6	bark	bark	NOUN
biomedich-691	117	7	of	of	ADP
biomedich-691	117	8	artocarpus	artocarpus	PROPN
biomedich-691	117	9	altilis	altilis	PROPN
biomedich-691	117	10	:	:	PUNCT
biomedich-691	117	11	promising	promise	VERB
biomedich-691	117	12	anticancer	anticancer	NOUN
biomedich-691	117	13	agents	agent	NOUN
biomedich-691	117	14	for	for	ADP
biomedich-691	117	15	oral	oral	ADJ
biomedich-691	117	16	squamous	squamous	ADJ
biomedich-691	117	17	cell	cell	NOUN
biomedich-691	117	18	carcinoma	carcinoma	NOUN
biomedich-691	117	19	targeting	target	VERB
biomedich-691	117	20	the	the	DET
biomedich-691	117	21	akt	akt	PROPN
biomedich-691	117	22	/	/	SYM
biomedich-691	117	23	mtor	mtor	PROPN
biomedich-691	117	24	/	/	SYM
biomedich-691	117	25	stat-3	stat-3	NUM
biomedich-691	117	26	signaling	signal	VERB
biomedich-691	117	27	pathway	pathway	NOUN
biomedich-691	117	28	.	.	PUNCT
biomedich-691	118	1	acs	acs	PROPN
biomedich-691	118	2	omega	omega	NOUN
biomedich-691	118	3	,	,	PUNCT
biomedich-691	118	4	9(23	9(23	NOUN
biomedich-691	118	5	)	)	PUNCT
biomedich-691	118	6	,	,	PUNCT
biomedich-691	118	7	24252–24267	24252–24267	NUM
biomedich-691	118	8	.	.	PUNCT
biomedich-691	119	1	https://doi.org/10.1021/acsomega.3c08376	https://doi.org/10.1021/acsomega.3c08376	PROPN
biomedich-691	119	2	dai	dai	PROPN
biomedich-691	119	3	,	,	PUNCT
biomedich-691	119	4	w.	w.	PROPN
biomedich-691	119	5	,	,	PUNCT
biomedich-691	119	6	chen	chen	PROPN
biomedich-691	119	7	,	,	PUNCT
biomedich-691	119	8	h.	h.	PROPN
biomedich-691	119	9	y.	y.	PROPN
biomedich-691	119	10	,	,	PUNCT
biomedich-691	119	11	&	&	CCONJ
biomedich-691	119	12	chen	chen	PROPN
biomedich-691	119	13	,	,	PUNCT
biomedich-691	119	14	c.	c.	PROPN
biomedich-691	119	15	y.	y.	PROPN
biomedich-691	119	16	c.	c.	PROPN
biomedich-691	119	17	(	(	PUNCT
biomedich-691	119	18	2018	2018	NUM
biomedich-691	119	19	)	)	PUNCT
biomedich-691	119	20	.	.	PUNCT
biomedich-691	120	1	a	a	DET
biomedich-691	120	2	network	network	NOUN
biomedich-691	120	3	pharmacology	pharmacology	NOUN
biomedich-691	120	4	-	-	PUNCT
biomedich-691	120	5	based	base	VERB
biomedich-691	120	6	approach	approach	NOUN
biomedich-691	120	7	to	to	PART
biomedich-691	120	8	investigate	investigate	VERB
biomedich-691	120	9	the	the	DET
biomedich-691	120	10	novel	novel	ADJ
biomedich-691	120	11	tcm	tcm	PROPN
biomedich-691	120	12	formula	formula	NOUN
biomedich-691	120	13	against	against	ADP
biomedich-691	120	14	huntington	huntington	PROPN
biomedich-691	120	15	’s	’s	PART
biomedich-691	120	16	disease	disease	NOUN
biomedich-691	120	17	and	and	CCONJ
biomedich-691	120	18	validated	validate	VERB
biomedich-691	120	19	by	by	ADP
biomedich-691	120	20	support	support	NOUN
biomedich-691	120	21	vector	vector	NOUN
biomedich-691	120	22	machine	machine	NOUN
biomedich-691	120	23	model	model	NOUN
biomedich-691	120	24	.	.	PUNCT
biomedich-691	121	1	evidence	evidence	NOUN
biomedich-691	121	2	-	-	PUNCT
biomedich-691	121	3	based	base	VERB
biomedich-691	121	4	complementary	complementary	ADJ
biomedich-691	121	5	and	and	CCONJ
biomedich-691	121	6	alternative	alternative	ADJ
biomedich-691	121	7	medicine	medicine	NOUN
biomedich-691	121	8	,	,	PUNCT
biomedich-691	121	9	2018	2018	NUM
biomedich-691	121	10	.	.	PUNCT
biomedich-691	122	1	https://doi.org/10.1155/2018/6020197	https://doi.org/10.1155/2018/6020197	PROPN
biomedich-691	122	2	dallakyan	dallakyan	PROPN
biomedich-691	122	3	,	,	PUNCT
biomedich-691	122	4	s.	s.	PROPN
biomedich-691	122	5	,	,	PUNCT
biomedich-691	122	6	&	&	CCONJ
biomedich-691	122	7	olson	olson	PROPN
biomedich-691	122	8	,	,	PUNCT
biomedich-691	122	9	a.	a.	PROPN
biomedich-691	122	10	j.	j.	PROPN
biomedich-691	122	11	(	(	PUNCT
biomedich-691	122	12	2015	2015	NUM
biomedich-691	122	13	)	)	PUNCT
biomedich-691	122	14	.	.	PUNCT
biomedich-691	123	1	small	small	ADJ
biomedich-691	123	2	-	-	PUNCT
biomedich-691	123	3	molecule	molecule	NOUN
biomedich-691	123	4	library	library	NOUN
biomedich-691	123	5	screening	screening	NOUN
biomedich-691	123	6	by	by	ADP
biomedich-691	123	7	docking	dock	VERB
biomedich-691	123	8	with	with	ADP
biomedich-691	123	9	pyrx	pyrx	NOUN
biomedich-691	123	10	.	.	PUNCT
biomedich-691	124	1	methods	method	NOUN
biomedich-691	124	2	in	in	ADP
biomedich-691	124	3	molecular	molecular	ADJ
biomedich-691	124	4	biology	biology	NOUN
biomedich-691	124	5	,	,	PUNCT
biomedich-691	124	6	1263	1263	NUM
biomedich-691	124	7	,	,	PUNCT
biomedich-691	124	8	243–250	243–250	NUM
biomedich-691	124	9	.	.	PUNCT
biomedich-691	125	1	https://doi.org/10.1007/978-1-49392269-7_19	https://doi.org/10.1007/978-1-49392269-7_19	PROPN
biomedich-691	125	2	di	di	PROPN
biomedich-691	125	3	nardo	nardo	PROPN
biomedich-691	125	4	,	,	PUNCT
biomedich-691	125	5	p.	p.	PROPN
biomedich-691	125	6	,	,	PUNCT
biomedich-691	125	7	lisanti	lisanti	PROPN
biomedich-691	125	8	,	,	PUNCT
biomedich-691	125	9	c.	c.	PROPN
biomedich-691	125	10	,	,	PUNCT
biomedich-691	125	11	garutti	garutti	PROPN
biomedich-691	125	12	,	,	PUNCT
biomedich-691	125	13	m.	m.	NOUN
biomedich-691	125	14	,	,	PUNCT
biomedich-691	125	15	buriolla	buriolla	NOUN
biomedich-691	125	16	,	,	PUNCT
biomedich-691	125	17	s.	s.	PROPN
biomedich-691	125	18	,	,	PUNCT
biomedich-691	125	19	alberti	alberti	PROPN
biomedich-691	125	20	,	,	PUNCT
biomedich-691	125	21	m.	m.	NOUN
biomedich-691	125	22	,	,	PUNCT
biomedich-691	125	23	mazzeo	mazzeo	NOUN
biomedich-691	125	24	,	,	PUNCT
biomedich-691	125	25	r.	r.	PROPN
biomedich-691	125	26	,	,	PUNCT
biomedich-691	125	27	&	&	CCONJ
biomedich-691	125	28	puglisi	puglisi	VERB
biomedich-691	125	29	,	,	PUNCT
biomedich-691	125	30	f.	f.	PROPN
biomedich-691	125	31	(	(	PUNCT
biomedich-691	125	32	2022	2022	NUM
biomedich-691	125	33	)	)	PUNCT
biomedich-691	125	34	.	.	PUNCT
biomedich-691	126	1	chemotherapy	chemotherapy	NOUN
biomedich-691	126	2	in	in	ADP
biomedich-691	126	3	patients	patient	NOUN
biomedich-691	126	4	with	with	ADP
biomedich-691	126	5	early	early	ADJ
biomedich-691	126	6	breast	breast	NOUN
biomedich-691	126	7	cancer	cancer	NOUN
biomedich-691	126	8	:	:	PUNCT
biomedich-691	126	9	clinical	clinical	ADJ
biomedich-691	126	10	overview	overview	NOUN
biomedich-691	126	11	and	and	CCONJ
biomedich-691	126	12	management	management	NOUN
biomedich-691	126	13	of	of	ADP
biomedich-691	126	14	long	long	ADJ
biomedich-691	126	15	-	-	PUNCT
biomedich-691	126	16	term	term	NOUN
biomedich-691	126	17	side	side	NOUN
biomedich-691	126	18	effects	effect	NOUN
biomedich-691	126	19	.	.	PUNCT
biomedich-691	127	1	in	in	ADP
biomedich-691	127	2	expert	expert	ADJ
biomedich-691	127	3	opinion	opinion	NOUN
biomedich-691	127	4	on	on	ADP
biomedich-691	127	5	drug	drug	NOUN
biomedich-691	127	6	safety	safety	NOUN
biomedich-691	127	7	(	(	PUNCT
biomedich-691	127	8	vol	vol	NOUN
biomedich-691	127	9	.	.	PROPN
biomedich-691	127	10	21	21	NUM
biomedich-691	127	11	,	,	PUNCT
biomedich-691	127	12	issue	issue	NOUN
biomedich-691	127	13	11	11	NUM
biomedich-691	127	14	,	,	PUNCT
biomedich-691	127	15	pp	pp	ADJ
biomedich-691	127	16	.	.	PUNCT
biomedich-691	127	17	1341–1355	1341–1355	NUM
biomedich-691	127	18	)	)	PUNCT
biomedich-691	127	19	.	.	PUNCT
biomedich-691	128	1	taylor	taylor	PROPN
biomedich-691	128	2	and	and	CCONJ
biomedich-691	128	3	francis	francis	PROPN
biomedich-691	128	4	ltd	ltd	PROPN
biomedich-691	128	5	.	.	PROPN
biomedich-691	128	6	https://doi.org/10.1080/14740338.2022.2151584	https://doi.org/10.1080/14740338.2022.2151584	PROPN
biomedich-691	128	7	dong	dong	PROPN
biomedich-691	128	8	,	,	PUNCT
biomedich-691	128	9	j.	j.	PROPN
biomedich-691	128	10	,	,	PUNCT
biomedich-691	128	11	wang	wang	PROPN
biomedich-691	128	12	,	,	PUNCT
biomedich-691	128	13	n.	n.	PROPN
biomedich-691	128	14	n.	n.	PROPN
biomedich-691	128	15	,	,	PUNCT
biomedich-691	128	16	yao	yao	PROPN
biomedich-691	128	17	,	,	PUNCT
biomedich-691	128	18	z.	z.	PROPN
biomedich-691	128	19	j.	j.	PROPN
biomedich-691	128	20	,	,	PUNCT
biomedich-691	128	21	zhang	zhang	PROPN
biomedich-691	128	22	,	,	PUNCT
biomedich-691	128	23	l.	l.	PROPN
biomedich-691	128	24	,	,	PUNCT
biomedich-691	128	25	cheng	cheng	PROPN
biomedich-691	128	26	,	,	PUNCT
biomedich-691	128	27	y.	y.	PROPN
biomedich-691	128	28	,	,	PUNCT
biomedich-691	128	29	ouyang	ouyang	PROPN
biomedich-691	128	30	,	,	PUNCT
biomedich-691	128	31	d.	d.	PROPN
biomedich-691	128	32	,	,	PUNCT
biomedich-691	128	33	lu	lu	PROPN
biomedich-691	128	34	,	,	PUNCT
biomedich-691	128	35	a.	a.	NOUN
biomedich-691	128	36	p.	p.	PROPN
biomedich-691	128	37	,	,	PUNCT
biomedich-691	128	38	&	&	CCONJ
biomedich-691	128	39	cao	cao	PROPN
biomedich-691	128	40	,	,	PUNCT
biomedich-691	128	41	d.	d.	PROPN
biomedich-691	128	42	s.	s.	PROPN
biomedich-691	128	43	(	(	PUNCT
biomedich-691	128	44	2018	2018	NUM
biomedich-691	128	45	)	)	PUNCT
biomedich-691	128	46	.	.	PUNCT
biomedich-691	129	1	admetlab	admetlab	NOUN
biomedich-691	129	2	:	:	PUNCT
biomedich-691	129	3	a	a	DET
biomedich-691	129	4	platform	platform	NOUN
biomedich-691	129	5	for	for	ADP
biomedich-691	129	6	systematic	systematic	ADJ
biomedich-691	129	7	admet	admet	NOUN
biomedich-691	129	8	evaluation	evaluation	NOUN
biomedich-691	129	9	based	base	VERB
biomedich-691	129	10	on	on	ADP
biomedich-691	129	11	a	a	DET
biomedich-691	129	12	comprehensively	comprehensively	ADV
biomedich-691	129	13	collected	collect	VERB
biomedich-691	129	14	admet	admet	PROPN
biomedich-691	129	15	database	database	PROPN
biomedich-691	129	16	.	.	PUNCT
biomedich-691	130	1	journal	journal	PROPN
biomedich-691	130	2	of	of	ADP
biomedich-691	130	3	cheminformatics	cheminformatic	NOUN
biomedich-691	130	4	,	,	PUNCT
biomedich-691	130	5	10(1	10(1	NUM
biomedich-691	130	6	)	)	PUNCT
biomedich-691	130	7	.	.	PUNCT
biomedich-691	131	1	https://doi.org/10.1186/s13321-018-0283-x	https://doi.org/10.1186/s13321-018-0283-x	PROPN
biomedich-691	131	2	ganeson	ganeson	NOUN
biomedich-691	131	3	,	,	PUNCT
biomedich-691	131	4	s.	s.	PROPN
biomedich-691	131	5	,	,	PUNCT
biomedich-691	131	6	jamil	jamil	PROPN
biomedich-691	131	7	,	,	PUNCT
biomedich-691	131	8	m.	m.	PROPN
biomedich-691	131	9	m.	m.	PROPN
biomedich-691	131	10	a.	a.	PROPN
biomedich-691	131	11	,	,	PUNCT
biomedich-691	131	12	adon	adon	PROPN
biomedich-691	131	13	,	,	PUNCT
biomedich-691	131	14	m.	m.	NOUN
biomedich-691	131	15	n.	n.	PROPN
biomedich-691	131	16	,	,	PUNCT
biomedich-691	131	17	wahab	wahab	PROPN
biomedich-691	131	18	,	,	PUNCT
biomedich-691	131	19	r.	r.	PROPN
biomedich-691	131	20	a.	a.	PROPN
biomedich-691	131	21	,	,	PUNCT
biomedich-691	131	22	&	&	CCONJ
biomedich-691	131	23	ahmad	ahmad	PROPN
biomedich-691	131	24	,	,	PUNCT
biomedich-691	131	25	m.	m.	NOUN
biomedich-691	131	26	s.	s.	PROPN
biomedich-691	131	27	(	(	PUNCT
biomedich-691	131	28	2018	2018	NUM
biomedich-691	131	29	)	)	PUNCT
biomedich-691	131	30	.	.	PUNCT
biomedich-691	132	1	artocarpus	artocarpus	PROPN
biomedich-691	132	2	altilis	altilis	PROPN
biomedich-691	132	3	compound	compound	PROPN
biomedich-691	132	4	based	base	VERB
biomedich-691	132	5	study	study	NOUN
biomedich-691	132	6	for	for	ADP
biomedich-691	132	7	anti	anti	ADJ
biomedich-691	132	8	-	-	ADJ
biomedich-691	132	9	cancer	cancer	ADJ
biomedich-691	132	10	proliferation	proliferation	NOUN
biomedich-691	132	11	on	on	ADP
biomedich-691	132	12	hela	hela	ADJ
biomedich-691	132	13	cell	cell	NOUN
biomedich-691	132	14	via	via	ADP
biomedich-691	132	15	electroporation	electroporation	NOUN
biomedich-691	132	16	method	method	NOUN
biomedich-691	132	17	.	.	PUNCT
biomedich-691	133	1	journal	journal	NOUN
biomedich-691	133	2	of	of	ADP
biomedich-691	133	3	fundamental	fundamental	ADJ
biomedich-691	133	4	and	and	CCONJ
biomedich-691	133	5	applied	applied	ADJ
biomedich-691	133	6	sciences	science	NOUN
biomedich-691	133	7	,	,	PUNCT
biomedich-691	133	8	9(4s	9(4s	NUM
biomedich-691	133	9	)	)	PUNCT
biomedich-691	133	10	,	,	PUNCT
biomedich-691	133	11	310	310	NUM
biomedich-691	133	12	.	.	PUNCT
biomedich-691	134	1	https://doi.org/10.4314/jfas.v9i4s.18	https://doi.org/10.4314/jfas.v9i4s.18	PROPN
biomedich-691	134	2	goedendorp	goedendorp	PROPN
biomedich-691	134	3	,	,	PUNCT
biomedich-691	134	4	m.	m.	NOUN
biomedich-691	134	5	m.	m.	NOUN
biomedich-691	134	6	,	,	PUNCT
biomedich-691	134	7	andrykowski	andrykowski	PROPN
biomedich-691	134	8	,	,	PUNCT
biomedich-691	134	9	m.	m.	NOUN
biomedich-691	134	10	a.	a.	PROPN
biomedich-691	134	11	,	,	PUNCT
biomedich-691	134	12	donovan	donovan	PROPN
biomedich-691	134	13	,	,	PUNCT
biomedich-691	134	14	k.	k.	PROPN
biomedich-691	134	15	a.	a.	PROPN
biomedich-691	134	16	,	,	PUNCT
biomedich-691	134	17	jim	jim	PROPN
biomedich-691	134	18	,	,	PUNCT
biomedich-691	134	19	h.	h.	PROPN
biomedich-691	134	20	s.	s.	PROPN
biomedich-691	134	21	,	,	PUNCT
biomedich-691	134	22	phillips	phillips	PROPN
biomedich-691	134	23	,	,	PUNCT
biomedich-691	134	24	k.	k.	PROPN
biomedich-691	134	25	m.	m.	PROPN
biomedich-691	134	26	,	,	PUNCT
biomedich-691	134	27	small	small	ADJ
biomedich-691	134	28	,	,	PUNCT
biomedich-691	134	29	b.	b.	PROPN
biomedich-691	134	30	j.	j.	PROPN
biomedich-691	134	31	,	,	PUNCT
biomedich-691	134	32	laronga	laronga	PROPN
biomedich-691	134	33	,	,	PUNCT
biomedich-691	134	34	c.	c.	PROPN
biomedich-691	134	35	,	,	PUNCT
biomedich-691	134	36	&	&	CCONJ
biomedich-691	134	37	jacobsen	jacobsen	PROPN
biomedich-691	134	38	,	,	PUNCT
biomedich-691	134	39	p.	p.	PROPN
biomedich-691	134	40	b.	b.	PROPN
biomedich-691	135	1	(	(	PUNCT
biomedich-691	135	2	2012	2012	NUM
biomedich-691	135	3	)	)	PUNCT
biomedich-691	135	4	.	.	PUNCT
biomedich-691	136	1	prolonged	prolong	VERB
biomedich-691	136	2	impact	impact	NOUN
biomedich-691	136	3	of	of	ADP
biomedich-691	136	4	chemotherapy	chemotherapy	NOUN
biomedich-691	136	5	on	on	ADP
biomedich-691	136	6	fatigue	fatigue	NOUN
biomedich-691	136	7	in	in	ADP
biomedich-691	136	8	breast	breast	NOUN
biomedich-691	136	9	cancer	cancer	NOUN
biomedich-691	136	10	survivors	survivor	NOUN
biomedich-691	136	11	:	:	PUNCT
biomedich-691	136	12	a	a	DET
biomedich-691	136	13	longitudinal	longitudinal	ADJ
biomedich-691	136	14	comparison	comparison	NOUN
biomedich-691	136	15	with	with	ADP
biomedich-691	136	16	radiotherapy	radiotherapy	NOUN
biomedich-691	136	17	-	-	PUNCT
biomedich-691	136	18	treated	treat	VERB
biomedich-691	136	19	breast	breast	NOUN
biomedich-691	136	20	cancer	cancer	NOUN
biomedich-691	136	21	survivors	survivor	NOUN
biomedich-691	136	22	and	and	CCONJ
biomedich-691	136	23	noncancer	noncancer	NOUN
biomedich-691	136	24	controls	control	NOUN
biomedich-691	136	25	.	.	PUNCT
biomedich-691	137	1	cancer	cancer	NOUN
biomedich-691	137	2	,	,	PUNCT
biomedich-691	137	3	118(15	118(15	NUM
biomedich-691	137	4	)	)	PUNCT
biomedich-691	137	5	,	,	PUNCT
biomedich-691	137	6	3833–3841	3833–3841	NUM
biomedich-691	137	7	.	.	PUNCT
biomedich-691	138	1	https://doi.org/10.1002/cncr.26226	https://doi.org/10.1002/cncr.26226	PROPN
biomedich-691	138	2	guan	guan	PROPN
biomedich-691	138	3	,	,	PUNCT
biomedich-691	138	4	l.	l.	PROPN
biomedich-691	138	5	,	,	PUNCT
biomedich-691	138	6	yang	yang	PROPN
biomedich-691	138	7	,	,	PUNCT
biomedich-691	138	8	h.	h.	PROPN
biomedich-691	138	9	,	,	PUNCT
biomedich-691	138	10	cai	cai	PROPN
biomedich-691	138	11	,	,	PUNCT
biomedich-691	138	12	y.	y.	PROPN
biomedich-691	138	13	,	,	PUNCT
biomedich-691	138	14	sun	sun	PROPN
biomedich-691	138	15	,	,	PUNCT
biomedich-691	138	16	l.	l.	PROPN
biomedich-691	138	17	,	,	PUNCT
biomedich-691	138	18	di	di	PROPN
biomedich-691	138	19	,	,	PUNCT
biomedich-691	138	20	p.	p.	PROPN
biomedich-691	138	21	,	,	PUNCT
biomedich-691	138	22	li	li	PROPN
biomedich-691	138	23	,	,	PUNCT
biomedich-691	138	24	w.	w.	PROPN
biomedich-691	138	25	,	,	PUNCT
biomedich-691	138	26	&	&	CCONJ
biomedich-691	138	27	liu	liu	PROPN
biomedich-691	138	28	,	,	PUNCT
biomedich-691	138	29	g.	g.	PROPN
biomedich-691	138	30	(	(	PUNCT
biomedich-691	138	31	2018	2018	NUM
biomedich-691	138	32	)	)	PUNCT
biomedich-691	138	33	.	.	PUNCT
biomedich-691	139	1	admet	admet	NOUN
biomedich-691	139	2	-	-	PUNCT
biomedich-691	139	3	score	score	NOUN
biomedich-691	139	4	–	–	PUNCT
biomedich-691	139	5	a	a	DET
biomedich-691	139	6	comprehensive	comprehensive	ADJ
biomedich-691	139	7	scoring	scoring	NOUN
biomedich-691	139	8	function	function	NOUN
biomedich-691	139	9	for	for	ADP
biomedich-691	139	10	evaluation	evaluation	NOUN
biomedich-691	139	11	of	of	ADP
biomedich-691	139	12	chemical	chemical	ADJ
biomedich-691	139	13	drug	drug	NOUN
biomedich-691	139	14	-	-	PUNCT
biomedich-691	139	15	likeness	likeness	NOUN
biomedich-691	139	16	.	.	PUNCT
biomedich-691	140	1	medchemcomm	medchemcomm	NOUN
biomedich-691	140	2	.	.	PUNCT
biomedich-691	141	1	hassan	hassan	PROPN
biomedich-691	141	2	,	,	PUNCT
biomedich-691	141	3	a.	a.	NOUN
biomedich-691	141	4	m.	m.	NOUN
biomedich-691	141	5	,	,	PUNCT
biomedich-691	141	6	dhumad	dhumad	PROPN
biomedich-691	141	7	,	,	PUNCT
biomedich-691	141	8	a.	a.	NOUN
biomedich-691	141	9	m.	m.	NOUN
biomedich-691	141	10	,	,	PUNCT
biomedich-691	141	11	al	al	PROPN
biomedich-691	141	12	-	-	PUNCT
biomedich-691	141	13	asadi	asadi	PROPN
biomedich-691	141	14	,	,	PUNCT
biomedich-691	141	15	r.	r.	PROPN
biomedich-691	141	16	,	,	PUNCT
biomedich-691	141	17	&	&	CCONJ
biomedich-691	141	18	jassem	jassem	PROPN
biomedich-691	141	19	,	,	PUNCT
biomedich-691	141	20	a.	a.	NOUN
biomedich-691	141	21	m.	m.	NOUN
biomedich-691	141	22	(	(	PUNCT
biomedich-691	141	23	2020	2020	NUM
biomedich-691	141	24	)	)	PUNCT
biomedich-691	141	25	.	.	PUNCT
biomedich-691	142	1	synthesis	synthesis	NOUN
biomedich-691	142	2	and	and	CCONJ
biomedich-691	142	3	molecular	molecular	ADJ
biomedich-691	142	4	docking	docking	NOUN
biomedich-691	142	5	of	of	ADP
biomedich-691	142	6	some	some	DET
biomedich-691	142	7	amic	amic	ADJ
biomedich-691	142	8	acid	acid	NOUN
biomedich-691	142	9	targeting	target	VERB
biomedich-691	142	10	breast	breast	NOUN
biomedich-691	142	11	cancer	cancer	NOUN
biomedich-691	142	12	.	.	PUNCT
biomedich-691	143	1	iop	iop	PROPN
biomedich-691	143	2	conference	conference	PROPN
biomedich-691	143	3	series	series	PROPN
biomedich-691	143	4	:	:	PUNCT
biomedich-691	143	5	materials	material	NOUN
biomedich-691	143	6	science	science	NOUN
biomedich-691	143	7	and	and	CCONJ
biomedich-691	143	8	engineering	engineering	NOUN
biomedich-691	143	9	,	,	PUNCT
biomedich-691	143	10	928(5	928(5	NUM
biomedich-691	143	11	)	)	PUNCT
biomedich-691	143	12	.	.	PUNCT
biomedich-691	144	1	https://doi.org/10.1088/1757-899x/928/5/052022	https://doi.org/10.1088/1757-899x/928/5/052022	PROPN
biomedich-691	144	2	ibrahim	ibrahim	PROPN
biomedich-691	144	3	,	,	PUNCT
biomedich-691	144	4	m.	m.	NOUN
biomedich-691	144	5	t.	t.	PROPN
biomedich-691	144	6	,	,	PUNCT
biomedich-691	144	7	uzairu	uzairu	PROPN
biomedich-691	144	8	,	,	PUNCT
biomedich-691	144	9	a.	a.	NOUN
biomedich-691	144	10	,	,	PUNCT
biomedich-691	144	11	shallangwa	shallangwa	PROPN
biomedich-691	144	12	,	,	PUNCT
biomedich-691	144	13	g.	g.	PROPN
biomedich-691	144	14	a.	a.	PROPN
biomedich-691	144	15	,	,	PUNCT
biomedich-691	144	16	&	&	CCONJ
biomedich-691	144	17	uba	uba	PROPN
biomedich-691	144	18	,	,	PUNCT
biomedich-691	144	19	s.	s.	PROPN
biomedich-691	144	20	(	(	PUNCT
biomedich-691	144	21	2020	2020	NUM
biomedich-691	144	22	)	)	PUNCT
biomedich-691	144	23	.	.	PUNCT
biomedich-691	145	1	structure	structure	NOUN
biomedich-691	145	2	-	-	PUNCT
biomedich-691	145	3	based	base	VERB
biomedich-691	145	4	design	design	NOUN
biomedich-691	145	5	of	of	ADP
biomedich-691	145	6	some	some	DET
biomedich-691	145	7	quinazoline	quinazoline	ADJ
biomedich-691	145	8	derivatives	derivative	NOUN
biomedich-691	145	9	as	as	ADP
biomedich-691	145	10	epidermal	epidermal	ADJ
biomedich-691	145	11	growth	growth	NOUN
biomedich-691	145	12	factor	factor	NOUN
biomedich-691	145	13	receptor	receptor	NOUN
biomedich-691	145	14	inhibitors	inhibitor	NOUN
biomedich-691	145	15	.	.	PUNCT
biomedich-691	146	1	egyptian	egyptian	ADJ
biomedich-691	146	2	journal	journal	PROPN
biomedich-691	146	3	of	of	ADP
biomedich-691	146	4	medical	medical	ADJ
biomedich-691	146	5	human	human	ADJ
biomedich-691	146	6	genetics	genetic	NOUN
biomedich-691	146	7	,	,	PUNCT
biomedich-691	146	8	21(1	21(1	NUM
biomedich-691	146	9	)	)	PUNCT
biomedich-691	146	10	.	.	PUNCT
biomedich-691	147	1	https://doi.org/10.1186/s43042-020-00107-y	https://doi.org/10.1186/s43042-020-00107-y	NOUN
biomedich-691	147	2	jantapaso	jantapaso	PROPN
biomedich-691	147	3	,	,	PUNCT
biomedich-691	147	4	h.	h.	PROPN
biomedich-691	147	5	,	,	PUNCT
biomedich-691	147	6	&	&	CCONJ
biomedich-691	147	7	mittraparp	mittraparp	PROPN
biomedich-691	147	8	-	-	PUNCT
biomedich-691	147	9	arthorn	arthorn	ADJ
biomedich-691	147	10	,	,	PUNCT
biomedich-691	147	11	p.	p.	NOUN
biomedich-691	147	12	(	(	PUNCT
biomedich-691	147	13	2022	2022	NUM
biomedich-691	147	14	)	)	PUNCT
biomedich-691	147	15	.	.	PUNCT
biomedich-691	148	1	phytochemical	phytochemical	ADJ
biomedich-691	148	2	composition	composition	NOUN
biomedich-691	148	3	and	and	CCONJ
biomedich-691	148	4	bioactivities	bioactivitie	NOUN
biomedich-691	148	5	of	of	ADP
biomedich-691	148	6	aqueous	aqueous	ADJ
biomedich-691	148	7	extract	extract	NOUN
biomedich-691	148	8	of	of	ADP
biomedich-691	148	9	rambutan	rambutan	PROPN
biomedich-691	148	10	(	(	PUNCT
biomedich-691	148	11	nephelium	nephelium	NOUN
biomedich-691	148	12	lappaceum	lappaceum	PROPN
biomedich-691	148	13	l.	l.	PROPN
biomedich-691	148	14	cv	cv	PROPN
biomedich-691	148	15	.	.	PROPN
biomedich-691	148	16	rong	rong	PROPN
biomedich-691	148	17	rian	rian	PROPN
biomedich-691	148	18	)	)	PUNCT
biomedich-691	148	19	peel	peel	NOUN
biomedich-691	148	20	.	.	PUNCT
biomedich-691	149	1	antioxidants	antioxidant	NOUN
biomedich-691	149	2	,	,	PUNCT
biomedich-691	149	3	11(5	11(5	NUM
biomedich-691	149	4	)	)	PUNCT
biomedich-691	149	5	.	.	PUNCT
biomedich-691	150	1	https://doi.org/10.3390/antiox11050956	https://doi.org/10.3390/antiox11050956	PROPN
biomedich-691	150	2	lestariningrum	lestariningrum	PROPN
biomedich-691	150	3	,	,	PUNCT
biomedich-691	150	4	w.	w.	PROPN
biomedich-691	150	5	t.	t.	PROPN
biomedich-691	150	6	,	,	PUNCT
biomedich-691	150	7	kintoko	kintoko	PROPN
biomedich-691	150	8	,	,	PUNCT
biomedich-691	150	9	k.	k.	PROPN
biomedich-691	150	10	,	,	PUNCT
biomedich-691	150	11	&	&	CCONJ
biomedich-691	150	12	farid	farid	PROPN
biomedich-691	150	13	,	,	PUNCT
biomedich-691	150	14	m.	m.	NOUN
biomedich-691	150	15	(	(	PUNCT
biomedich-691	150	16	2024	2024	NUM
biomedich-691	150	17	)	)	PUNCT
biomedich-691	150	18	.	.	PUNCT
biomedich-691	151	1	integrated	integrate	VERB
biomedich-691	151	2	ethnomedicine	ethnomedicine	NOUN
biomedich-691	151	3	study	study	NOUN
biomedich-691	151	4	in	in	ADP
biomedich-691	151	5	silico	silico	NOUN
biomedich-691	151	6	of	of	ADP
biomedich-691	151	7	medicinal	medicinal	ADJ
biomedich-691	151	8	plants	plant	NOUN
biomedich-691	151	9	for	for	ADP
biomedich-691	151	10	hypertension	hypertension	NOUN
biomedich-691	151	11	.	.	PUNCT
biomedich-691	152	1	journal	journal	PROPN
biomedich-691	152	2	la	la	PROPN
biomedich-691	152	3	lifesci	lifesci	PROPN
biomedich-691	152	4	,	,	PUNCT
biomedich-691	152	5	5(5	5(5	NUM
biomedich-691	152	6	)	)	PUNCT
biomedich-691	152	7	,	,	PUNCT
biomedich-691	152	8	483–501	483–501	NUM
biomedich-691	152	9	.	.	PUNCT
biomedich-691	153	1	https://doi.org/10.37899/journallalifesci.v5i5.1656	https://doi.org/10.37899/journallalifesci.v5i5.1656	PROPN
biomedich-691	153	2	meng	meng	PROPN
biomedich-691	153	3	,	,	PUNCT
biomedich-691	153	4	x.-y	x.-y	PROPN
biomedich-691	153	5	.	.	PROPN
biomedich-691	153	6	,	,	PUNCT
biomedich-691	153	7	zhang	zhang	PROPN
biomedich-691	153	8	,	,	PUNCT
biomedich-691	153	9	h.-x	h.-x	NOUN
biomedich-691	153	10	.	.	PROPN
biomedich-691	153	11	,	,	PUNCT
biomedich-691	153	12	mezei	mezei	NOUN
biomedich-691	153	13	,	,	PUNCT
biomedich-691	153	14	m.	m.	NOUN
biomedich-691	153	15	,	,	PUNCT
biomedich-691	153	16	&	&	CCONJ
biomedich-691	153	17	cui	cui	PROPN
biomedich-691	153	18	,	,	PUNCT
biomedich-691	153	19	m.	m.	NOUN
biomedich-691	153	20	(	(	PUNCT
biomedich-691	153	21	2011	2011	NUM
biomedich-691	153	22	)	)	PUNCT
biomedich-691	153	23	.	.	PUNCT
biomedich-691	154	1	molecular	molecular	ADJ
biomedich-691	154	2	docking	docking	NOUN
biomedich-691	154	3	:	:	PUNCT
biomedich-691	154	4	a	a	DET
biomedich-691	154	5	powerful	powerful	ADJ
biomedich-691	154	6	approach	approach	NOUN
biomedich-691	154	7	for	for	ADP
biomedich-691	154	8	structure	structure	NOUN
biomedich-691	154	9	-	-	PUNCT
biomedich-691	154	10	based	base	VERB
biomedich-691	154	11	drug	drug	NOUN
biomedich-691	154	12	discovery	discovery	NOUN
biomedich-691	154	13	.	.	PUNCT
biomedich-691	155	1	in	in	ADP
biomedich-691	155	2	current	current	ADJ
biomedich-691	155	3	computer	computer	NOUN
biomedich-691	155	4	-	-	PUNCT
biomedich-691	155	5	aided	aid	VERB
biomedich-691	155	6	drug	drug	NOUN
biomedich-691	155	7	design	design	NOUN
biomedich-691	155	8	(	(	PUNCT
biomedich-691	155	9	vol	vol	NOUN
biomedich-691	155	10	.	.	NOUN
biomedich-691	155	11	7	7	NUM
biomedich-691	155	12	)	)	PUNCT
biomedich-691	155	13	.	.	PUNCT
biomedich-691	156	1	radwan	radwan	PROPN
biomedich-691	156	2	,	,	PUNCT
biomedich-691	156	3	a.	a.	NOUN
biomedich-691	156	4	a.	a.	PROPN
biomedich-691	156	5	,	,	PUNCT
biomedich-691	156	6	alanazi	alanazi	PROPN
biomedich-691	156	7	,	,	PUNCT
biomedich-691	156	8	f.	f.	PROPN
biomedich-691	156	9	,	,	PUNCT
biomedich-691	156	10	&	&	CCONJ
biomedich-691	156	11	al	al	PROPN
biomedich-691	156	12	-	-	PUNCT
biomedich-691	156	13	dhfyan	dhfyan	PROPN
biomedich-691	156	14	,	,	PUNCT
biomedich-691	156	15	a.	a.	NOUN
biomedich-691	156	16	(	(	PUNCT
biomedich-691	156	17	2024	2024	NUM
biomedich-691	156	18	)	)	PUNCT
biomedich-691	156	19	.	.	PUNCT
biomedich-691	157	1	bioinformatics	bioinformatics	NOUN
biomedich-691	157	2	-	-	PUNCT
biomedich-691	157	3	driven	drive	VERB
biomedich-691	157	4	discovery	discovery	NOUN
biomedich-691	157	5	of	of	ADP
biomedich-691	157	6	novel	novel	ADJ
biomedich-691	157	7	egfr	egfr	NOUN
biomedich-691	157	8	kinase	kinase	PROPN
biomedich-691	157	9	inhibitors	inhibitor	NOUN
biomedich-691	157	10	as	as	ADP
biomedich-691	157	11	anti	anti	ADJ
biomedich-691	157	12	-	-	ADJ
biomedich-691	157	13	cancer	cancer	ADJ
biomedich-691	157	14	therapeutics	therapeutic	NOUN
biomedich-691	157	15	:	:	PUNCT
biomedich-691	157	16	in	in	ADP
biomedich-691	157	17	silico	silico	NOUN
biomedich-691	157	18	screening	screening	NOUN
biomedich-691	157	19	and	and	CCONJ
biomedich-691	157	20	in	in	ADP
biomedich-691	157	21	vitro	vitro	X
biomedich-691	157	22	evaluation	evaluation	NOUN
biomedich-691	157	23	.	.	PUNCT
biomedich-691	158	1	plos	plos	PROPN
biomedich-691	158	2	one	one	NUM
biomedich-691	158	3	,	,	PUNCT
biomedich-691	158	4	19(4	19(4	PROPN
biomedich-691	158	5	april	april	PROPN
biomedich-691	158	6	)	)	PUNCT
biomedich-691	158	7	.	.	PUNCT
biomedich-691	159	1	https://doi.org/10.1371/journal.pone.0298326	https://doi.org/10.1371/journal.pone.0298326	NOUN
biomedich-691	159	2	sitarek	sitarek	NOUN
biomedich-691	159	3	,	,	PUNCT
biomedich-691	159	4	p.	p.	NOUN
biomedich-691	159	5	,	,	PUNCT
biomedich-691	159	6	merecz	merecz	PROPN
biomedich-691	159	7	-	-	PUNCT
biomedich-691	159	8	sadowska	sadowska	PROPN
biomedich-691	159	9	,	,	PUNCT
biomedich-691	159	10	a.	a.	NOUN
biomedich-691	159	11	,	,	PUNCT
biomedich-691	159	12	sikora	sikora	PROPN
biomedich-691	159	13	,	,	PUNCT
biomedich-691	159	14	j.	j.	PROPN
biomedich-691	159	15	,	,	PUNCT
biomedich-691	159	16	dudzic	dudzic	PROPN
biomedich-691	159	17	,	,	PUNCT
biomedich-691	159	18	m.	m.	NOUN
biomedich-691	159	19	,	,	PUNCT
biomedich-691	159	20	wiertekpłoszaj	wiertekpłoszaj	PROPN
biomedich-691	159	21	,	,	PUNCT
biomedich-691	159	22	n.	n.	PROPN
biomedich-691	159	23	,	,	PUNCT
biomedich-691	159	24	picot	picot	PROPN
biomedich-691	159	25	,	,	PUNCT
biomedich-691	159	26	l.	l.	PROPN
biomedich-691	159	27	,	,	PUNCT
biomedich-691	159	28	śliwiński	śliwiński	PROPN
biomedich-691	159	29	,	,	PUNCT
biomedich-691	159	30	t.	t.	PROPN
biomedich-691	159	31	,	,	PUNCT
biomedich-691	159	32	&	&	CCONJ
biomedich-691	159	33	kowalczyk	kowalczyk	VERB
biomedich-691	159	34	,	,	PUNCT
biomedich-691	159	35	t.	t.	PROPN
biomedich-691	159	36	(	(	PUNCT
biomedich-691	159	37	2024	2024	NUM
biomedich-691	159	38	)	)	PUNCT
biomedich-691	159	39	.	.	PUNCT
biomedich-691	160	1	flavonoids	flavonoid	NOUN
biomedich-691	160	2	and	and	CCONJ
biomedich-691	160	3	their	their	PRON
biomedich-691	160	4	derivatives	derivative	NOUN
biomedich-691	160	5	as	as	ADP
biomedich-691	160	6	dna	dna	PROPN
biomedich-691	160	7	topoisomerase	topoisomerase	VERB
biomedich-691	160	8	inhibitors	inhibitor	NOUN
biomedich-691	160	9	with	with	ADP
biomedich-691	160	10	anti	anti	ADJ
biomedich-691	160	11	-	-	ADJ
biomedich-691	160	12	cancer	cancer	ADJ
biomedich-691	160	13	activity	activity	NOUN
biomedich-691	160	14	in	in	ADP
biomedich-691	160	15	various	various	ADJ
biomedich-691	160	16	cell	cell	NOUN
biomedich-691	160	17	models	model	NOUN
biomedich-691	160	18	:	:	PUNCT
biomedich-691	160	19	exploring	explore	VERB
biomedich-691	160	20	a	a	DET
biomedich-691	160	21	novel	novel	ADJ
biomedich-691	160	22	mode	mode	NOUN
biomedich-691	160	23	of	of	ADP
biomedich-691	160	24	action	action	NOUN
biomedich-691	160	25	.	.	PUNCT
biomedich-691	161	1	in	in	ADP
biomedich-691	161	2	pharmacological	pharmacological	ADJ
biomedich-691	161	3	research	research	NOUN
biomedich-691	161	4	(	(	PUNCT
biomedich-691	161	5	vol	vol	NOUN
biomedich-691	161	6	.	.	NOUN
biomedich-691	161	7	209	209	NUM
biomedich-691	161	8	)	)	PUNCT
biomedich-691	161	9	.	.	PUNCT
biomedich-691	162	1	academic	academic	ADJ
biomedich-691	162	2	press	press	NOUN
biomedich-691	162	3	.	.	PUNCT
biomedich-691	163	1	https://doi.org/10.1016/j.phrs.2024.107457	https://doi.org/10.1016/j.phrs.2024.107457	PROPN
biomedich-691	163	2	soleymani	soleymani	PROPN
biomedich-691	163	3	,	,	PUNCT
biomedich-691	163	4	f.	f.	PROPN
biomedich-691	163	5	,	,	PUNCT
biomedich-691	163	6	paquet	paquet	PROPN
biomedich-691	163	7	,	,	PUNCT
biomedich-691	163	8	e.	e.	PROPN
biomedich-691	163	9	,	,	PUNCT
biomedich-691	163	10	viktor	viktor	PROPN
biomedich-691	163	11	,	,	PUNCT
biomedich-691	163	12	h.	h.	PROPN
biomedich-691	163	13	,	,	PUNCT
biomedich-691	163	14	michalowski	michalowski	PROPN
biomedich-691	163	15	,	,	PUNCT
biomedich-691	163	16	w.	w.	PROPN
biomedich-691	163	17	,	,	PUNCT
biomedich-691	163	18	&	&	CCONJ
biomedich-691	163	19	spinello	spinello	PROPN
biomedich-691	163	20	,	,	PUNCT
biomedich-691	163	21	d.	d.	PROPN
biomedich-691	163	22	(	(	PUNCT
biomedich-691	163	23	2022	2022	NUM
biomedich-691	163	24	)	)	PUNCT
biomedich-691	163	25	.	.	PUNCT
biomedich-691	164	1	protein	protein	NOUN
biomedich-691	164	2	–	–	PUNCT
biomedich-691	164	3	protein	protein	NOUN
biomedich-691	164	4	interaction	interaction	NOUN
biomedich-691	164	5	prediction	prediction	NOUN
biomedich-691	164	6	with	with	ADP
biomedich-691	164	7	deep	deep	ADJ
biomedich-691	164	8	learning	learning	NOUN
biomedich-691	164	9	:	:	PUNCT
biomedich-691	164	10	a	a	DET
biomedich-691	164	11	comprehensive	comprehensive	ADJ
biomedich-691	164	12	review	review	NOUN
biomedich-691	164	13	.	.	PUNCT
biomedich-691	165	1	in	in	ADP
biomedich-691	165	2	computational	computational	ADJ
biomedich-691	165	3	and	and	CCONJ
biomedich-691	165	4	structural	structural	ADJ
biomedich-691	165	5	biotechnology	biotechnology	NOUN
biomedich-691	165	6	journal	journal	NOUN
biomedich-691	165	7	(	(	PUNCT
biomedich-691	165	8	vol	vol	NOUN
biomedich-691	165	9	.	.	PROPN
biomedich-691	165	10	20	20	NUM
biomedich-691	165	11	,	,	PUNCT
biomedich-691	165	12	pp	pp	ADJ
biomedich-691	165	13	.	.	PUNCT
biomedich-691	165	14	5316–5341	5316–5341	NUM
biomedich-691	165	15	)	)	PUNCT
biomedich-691	165	16	.	.	PUNCT
biomedich-691	166	1	elsevier	elsevier	PROPN
biomedich-691	166	2	b.v	b.v	PROPN
biomedich-691	166	3	.	.	PROPN
biomedich-691	167	1	https://doi.org/10.1016/j.csbj.2022.08.070	https://doi.org/10.1016/j.csbj.2022.08.070	PROPN
biomedich-691	167	2	204	204	NUM
biomedich-691	167	3	biology	biology	NOUN
biomedich-691	167	4	,	,	PUNCT
biomedich-691	167	5	medicine	medicine	NOUN
biomedich-691	167	6	,	,	PUNCT
biomedich-691	167	7	&	&	CCONJ
biomedich-691	167	8	natural	natural	ADJ
biomedich-691	167	9	product	product	NOUN
biomedich-691	167	10	chemistry	chemistry	NOUN
biomedich-691	167	11	14	14	NUM
biomedich-691	167	12	(	(	PUNCT
biomedich-691	167	13	1	1	NUM
biomedich-691	167	14	)	)	PUNCT
biomedich-691	167	15	,	,	PUNCT
biomedich-691	167	16	2025	2025	NUM
biomedich-691	167	17	:	:	PUNCT
biomedich-691	167	18	199	199	NUM
biomedich-691	167	19	-	-	SYM
biomedich-691	167	20	204	204	NUM
biomedich-691	167	21	sung	sung	NOUN
biomedich-691	167	22	,	,	PUNCT
biomedich-691	167	23	h.	h.	PROPN
biomedich-691	167	24	,	,	PUNCT
biomedich-691	167	25	ferlay	ferlay	PROPN
biomedich-691	167	26	,	,	PUNCT
biomedich-691	167	27	j.	j.	PROPN
biomedich-691	167	28	,	,	PUNCT
biomedich-691	167	29	siegel	siegel	PROPN
biomedich-691	167	30	,	,	PUNCT
biomedich-691	167	31	r.	r.	PROPN
biomedich-691	167	32	l.	l.	PROPN
biomedich-691	167	33	,	,	PUNCT
biomedich-691	167	34	laversanne	laversanne	PROPN
biomedich-691	167	35	,	,	PUNCT
biomedich-691	167	36	m.	m.	NOUN
biomedich-691	167	37	,	,	PUNCT
biomedich-691	167	38	soerjomataram	soerjomataram	PROPN
biomedich-691	167	39	,	,	PUNCT
biomedich-691	167	40	i.	i.	NOUN
biomedich-691	167	41	,	,	PUNCT
biomedich-691	167	42	jemal	jemal	PROPN
biomedich-691	167	43	,	,	PUNCT
biomedich-691	167	44	a.	a.	NOUN
biomedich-691	167	45	,	,	PUNCT
biomedich-691	167	46	&	&	CCONJ
biomedich-691	167	47	bray	bray	PROPN
biomedich-691	167	48	,	,	PUNCT
biomedich-691	167	49	f.	f.	PROPN
biomedich-691	167	50	(	(	PUNCT
biomedich-691	167	51	2021	2021	NUM
biomedich-691	167	52	)	)	PUNCT
biomedich-691	167	53	.	.	PUNCT
biomedich-691	168	1	global	global	ADJ
biomedich-691	168	2	cancer	cancer	NOUN
biomedich-691	168	3	statistics	statistic	NOUN
biomedich-691	168	4	2020	2020	NUM
biomedich-691	168	5	:	:	PUNCT
biomedich-691	168	6	globocan	globocan	PROPN
biomedich-691	168	7	estimates	estimate	NOUN
biomedich-691	168	8	of	of	ADP
biomedich-691	168	9	incidence	incidence	NOUN
biomedich-691	168	10	and	and	CCONJ
biomedich-691	168	11	mortality	mortality	NOUN
biomedich-691	168	12	worldwide	worldwide	ADV
biomedich-691	168	13	for	for	ADP
biomedich-691	168	14	36	36	NUM
biomedich-691	168	15	cancers	cancer	NOUN
biomedich-691	168	16	in	in	ADP
biomedich-691	168	17	185	185	NUM
biomedich-691	168	18	countries	country	NOUN
biomedich-691	168	19	.	.	PUNCT
biomedich-691	169	1	ca	can	AUX
biomedich-691	169	2	:	:	PUNCT
biomedich-691	169	3	a	a	DET
biomedich-691	169	4	cancer	cancer	NOUN
biomedich-691	169	5	journal	journal	NOUN
biomedich-691	169	6	for	for	ADP
biomedich-691	169	7	clinicians	clinician	NOUN
biomedich-691	169	8	,	,	PUNCT
biomedich-691	169	9	71(3	71(3	NUM
biomedich-691	169	10	)	)	PUNCT
biomedich-691	169	11	,	,	PUNCT
biomedich-691	169	12	209–249	209–249	NUM
biomedich-691	169	13	.	.	PUNCT
biomedich-691	170	1	https://doi.org/10.3322/caac.21660	https://doi.org/10.3322/caac.21660	X
biomedich-691	170	2	syahputra	syahputra	PROPN
biomedich-691	170	3	,	,	PUNCT
biomedich-691	170	4	r.	r.	PROPN
biomedich-691	170	5	,	,	PUNCT
biomedich-691	170	6	utami	utami	NOUN
biomedich-691	170	7	,	,	PUNCT
biomedich-691	170	8	d.	d.	PROPN
biomedich-691	170	9	,	,	PUNCT
biomedich-691	170	10	&	&	CCONJ
biomedich-691	170	11	widyaningsih	widyaningsih	PROPN
biomedich-691	170	12	,	,	PUNCT
biomedich-691	170	13	w.	w.	PROPN
biomedich-691	170	14	(	(	PUNCT
biomedich-691	170	15	2022	2022	NUM
biomedich-691	170	16	)	)	PUNCT
biomedich-691	170	17	.	.	PUNCT
biomedich-691	171	1	studi	studi	PROPN
biomedich-691	171	2	docking	docking	NOUN
biomedich-691	171	3	molekuler	molekuler	NOUN
biomedich-691	171	4	aktivitas	aktivita	VERB
biomedich-691	171	5	penghambatan	penghambatan	PROPN
biomedich-691	171	6	enzim	enzim	PROPN
biomedich-691	171	7	tirosinase	tirosinase	PROPN
biomedich-691	171	8	ubi	ubi	PRON
biomedich-691	171	9	jalar	jalar	ADV
biomedich-691	171	10	(	(	PUNCT
biomedich-691	171	11	ipomoea	ipomoea	PROPN
biomedich-691	171	12	batatas	batatas	PROPN
biomedich-691	171	13	l.	l.	PROPN
biomedich-691	171	14	lam	lam	PROPN
biomedich-691	171	15	)	)	PUNCT
biomedich-691	171	16	.	.	PUNCT
biomedich-691	172	1	pharmacon	pharmacon	NOUN
biomedich-691	172	2	:	:	PUNCT
biomedich-691	172	3	jurnalfarmasi	jurnalfarmasi	PROPN
biomedich-691	172	4	indonesia	indonesia	PROPN
biomedich-691	172	5	,	,	PUNCT
biomedich-691	172	6	19(1	19(1	NUM
biomedich-691	172	7	)	)	PUNCT
biomedich-691	172	8	.	.	PUNCT
biomedich-691	173	1	http://pubchem.ncbi.n	http://pubchem.ncbi.n	PROPN
biomedich-691	173	2	wilson	wilson	PROPN
biomedich-691	173	3	,	,	PUNCT
biomedich-691	173	4	k.	k.	PROPN
biomedich-691	173	5	j.	j.	PROPN
biomedich-691	173	6	,	,	PUNCT
biomedich-691	173	7	gilmore	gilmore	PROPN
biomedich-691	173	8	,	,	PUNCT
biomedich-691	173	9	j.	j.	PROPN
biomedich-691	173	10	l.	l.	PROPN
biomedich-691	173	11	,	,	PUNCT
biomedich-691	173	12	foley	foley	PROPN
biomedich-691	173	13	,	,	PUNCT
biomedich-691	173	14	j.	j.	PROPN
biomedich-691	173	15	,	,	PUNCT
biomedich-691	173	16	lemmon	lemmon	PROPN
biomedich-691	173	17	,	,	PUNCT
biomedich-691	173	18	m.	m.	NOUN
biomedich-691	173	19	a.	a.	PROPN
biomedich-691	173	20	,	,	PUNCT
biomedich-691	173	21	&	&	CCONJ
biomedich-691	173	22	riese	riese	PROPN
biomedich-691	173	23	,	,	PUNCT
biomedich-691	173	24	d.	d.	PROPN
biomedich-691	173	25	j.	j.	PROPN
biomedich-691	173	26	(	(	PUNCT
biomedich-691	173	27	2009	2009	NUM
biomedich-691	173	28	)	)	PUNCT
biomedich-691	173	29	.	.	PUNCT
biomedich-691	174	1	functional	functional	ADJ
biomedich-691	174	2	selectivity	selectivity	NOUN
biomedich-691	174	3	of	of	ADP
biomedich-691	174	4	egf	egf	PROPN
biomedich-691	174	5	family	family	NOUN
biomedich-691	174	6	peptide	peptide	NOUN
biomedich-691	174	7	growth	growth	NOUN
biomedich-691	174	8	factors	factor	NOUN
biomedich-691	174	9	:	:	PUNCT
biomedich-691	174	10	implications	implication	NOUN
biomedich-691	174	11	for	for	ADP
biomedich-691	174	12	cancer	cancer	NOUN
biomedich-691	174	13	.	.	PUNCT
biomedich-691	175	1	in	in	ADP
biomedich-691	175	2	pharmacology	pharmacology	NOUN
biomedich-691	175	3	and	and	CCONJ
biomedich-691	175	4	therapeutics	therapeutic	NOUN
biomedich-691	175	5	(	(	PUNCT
biomedich-691	175	6	vol	vol	NOUN
biomedich-691	175	7	.	.	PROPN
biomedich-691	175	8	122	122	NUM
biomedich-691	175	9	,	,	PUNCT
biomedich-691	175	10	issue	issue	NOUN
biomedich-691	175	11	1	1	NUM
biomedich-691	175	12	,	,	PUNCT
biomedich-691	175	13	pp	pp	ADJ
biomedich-691	175	14	.	.	PUNCT
biomedich-691	175	15	1–8	1–8	X
biomedich-691	175	16	)	)	PUNCT
biomedich-691	175	17	.	.	PUNCT
biomedich-691	176	1	https://doi.org/10.1016/j.pharmthera.2008.11.008	https://doi.org/10.1016/j.pharmthera.2008.11.008	PROPN
biomedich-691	176	2	zamorano	zamorano	PROPN
biomedich-691	176	3	,	,	PUNCT
biomedich-691	176	4	j.	j.	PROPN
biomedich-691	176	5	l.	l.	PROPN
biomedich-691	176	6	,	,	PUNCT
biomedich-691	176	7	lancellotti	lancellotti	PROPN
biomedich-691	176	8	,	,	PUNCT
biomedich-691	176	9	p.	p.	NOUN
biomedich-691	176	10	,	,	PUNCT
biomedich-691	176	11	rodriguez	rodriguez	PROPN
biomedich-691	176	12	muñoz	muñoz	PROPN
biomedich-691	176	13	,	,	PUNCT
biomedich-691	176	14	d.	d.	PROPN
biomedich-691	176	15	,	,	PUNCT
biomedich-691	176	16	aboyans	aboyan	NOUN
biomedich-691	176	17	,	,	PUNCT
biomedich-691	176	18	v.	v.	ADV
biomedich-691	176	19	,	,	PUNCT
biomedich-691	176	20	asteggiano	asteggiano	PROPN
biomedich-691	176	21	,	,	PUNCT
biomedich-691	176	22	r.	r.	PROPN
biomedich-691	176	23	,	,	PUNCT
biomedich-691	176	24	galderisi	galderisi	VERB
biomedich-691	176	25	,	,	PUNCT
biomedich-691	176	26	m.	m.	NOUN
biomedich-691	176	27	,	,	PUNCT
biomedich-691	176	28	habib	habib	PROPN
biomedich-691	176	29	,	,	PUNCT
biomedich-691	176	30	g.	g.	PROPN
biomedich-691	176	31	,	,	PUNCT
biomedich-691	176	32	lenihan	lenihan	PROPN
biomedich-691	176	33	,	,	PUNCT
biomedich-691	176	34	d.	d.	PROPN
biomedich-691	176	35	j.	j.	PROPN
biomedich-691	176	36	,	,	PUNCT
biomedich-691	176	37	lip	lip	NOUN
biomedich-691	176	38	,	,	PUNCT
biomedich-691	176	39	g.	g.	PROPN
biomedich-691	176	40	y.	y.	PROPN
biomedich-691	176	41	h.	h.	PROPN
biomedich-691	176	42	,	,	PUNCT
biomedich-691	176	43	lyon	lyon	PROPN
biomedich-691	176	44	,	,	PUNCT
biomedich-691	176	45	a.	a.	PROPN
biomedich-691	176	46	r.	r.	PROPN
biomedich-691	176	47	,	,	PUNCT
biomedich-691	176	48	lopez	lopez	PROPN
biomedich-691	176	49	fernandez	fernandez	PROPN
biomedich-691	176	50	,	,	PUNCT
biomedich-691	176	51	t.	t.	PROPN
biomedich-691	176	52	,	,	PUNCT
biomedich-691	176	53	mohty	mohty	INTJ
biomedich-691	176	54	,	,	PUNCT
biomedich-691	176	55	d.	d.	PROPN
biomedich-691	176	56	,	,	PUNCT
biomedich-691	176	57	piepoli	piepoli	PROPN
biomedich-691	176	58	,	,	PUNCT
biomedich-691	176	59	m.	m.	NOUN
biomedich-691	176	60	f.	f.	PROPN
biomedich-691	176	61	,	,	PUNCT
biomedich-691	176	62	tamargo	tamargo	PROPN
biomedich-691	176	63	,	,	PUNCT
biomedich-691	176	64	j.	j.	PROPN
biomedich-691	176	65	,	,	PUNCT
biomedich-691	176	66	torbicki	torbicki	PROPN
biomedich-691	176	67	,	,	PUNCT
biomedich-691	176	68	a.	a.	NOUN
biomedich-691	176	69	,	,	PUNCT
biomedich-691	176	70	suter	suter	NOUN
biomedich-691	176	71	,	,	PUNCT
biomedich-691	176	72	t.	t.	NOUN
biomedich-691	176	73	m.	m.	NOUN
biomedich-691	176	74	,	,	PUNCT
biomedich-691	176	75	achenbach	achenbach	PROPN
biomedich-691	176	76	,	,	PUNCT
biomedich-691	176	77	s.	s.	PROPN
biomedich-691	176	78	,	,	PUNCT
biomedich-691	176	79	agewall	agewall	PROPN
biomedich-691	176	80	,	,	PUNCT
biomedich-691	176	81	s.	s.	PROPN
biomedich-691	176	82	,	,	PUNCT
biomedich-691	176	83	badimon	badimon	PROPN
biomedich-691	176	84	,	,	PUNCT
biomedich-691	176	85	l.	l.	PROPN
biomedich-691	176	86	,	,	PUNCT
biomedich-691	176	87	…	…	PUNCT
biomedich-691	176	88	szmit	szmit	NOUN
biomedich-691	176	89	,	,	PUNCT
biomedich-691	176	90	s.	s.	PROPN
biomedich-691	176	91	(	(	PUNCT
biomedich-691	176	92	2016	2016	NUM
biomedich-691	176	93	)	)	PUNCT
biomedich-691	176	94	.	.	PUNCT
biomedich-691	177	1	2016	2016	NUM
biomedich-691	177	2	esc	esc	NOUN
biomedich-691	177	3	position	position	NOUN
biomedich-691	177	4	paper	paper	NOUN
biomedich-691	177	5	on	on	ADP
biomedich-691	177	6	cancer	cancer	NOUN
biomedich-691	177	7	treatments	treatment	NOUN
biomedich-691	177	8	and	and	CCONJ
biomedich-691	177	9	cardiovascular	cardiovascular	ADJ
biomedich-691	177	10	toxicity	toxicity	NOUN
biomedich-691	177	11	developed	develop	VERB
biomedich-691	177	12	under	under	ADP
biomedich-691	177	13	the	the	DET
biomedich-691	177	14	auspices	auspex	NOUN
biomedich-691	177	15	of	of	ADP
biomedich-691	177	16	the	the	DET
biomedich-691	177	17	esc	esc	NOUN
biomedich-691	177	18	committee	committee	PROPN
biomedich-691	177	19	for	for	ADP
biomedich-691	177	20	practice	practice	NOUN
biomedich-691	177	21	guidelines	guideline	NOUN
biomedich-691	177	22	.	.	PUNCT
biomedich-691	178	1	in	in	ADP
biomedich-691	178	2	european	european	ADJ
biomedich-691	178	3	heart	heart	PROPN
biomedich-691	178	4	journal	journal	PROPN
biomedich-691	178	5	(	(	PUNCT
biomedich-691	178	6	vol	vol	NOUN
biomedich-691	178	7	.	.	PUNCT
biomedich-691	178	8	37	37	NUM
biomedich-691	178	9	,	,	PUNCT
biomedich-691	178	10	issue	issue	NOUN
biomedich-691	178	11	36	36	NUM
biomedich-691	178	12	,	,	PUNCT
biomedich-691	178	13	pp	pp	ADJ
biomedich-691	178	14	.	.	PUNCT
biomedich-691	178	15	2768–2801	2768–2801	NUM
biomedich-691	178	16	)	)	PUNCT
biomedich-691	178	17	.	.	PUNCT
biomedich-691	179	1	oxford	oxford	PROPN
biomedich-691	179	2	university	university	PROPN
biomedich-691	179	3	press	press	NOUN
biomedich-691	179	4	.	.	PUNCT
biomedich-691	180	1	https://doi.org/10.1093/eurheartj/ehw211	https://doi.org/10.1093/eurheartj/ehw211	PRON