id	sid	tid	token	lemma	pos
biomedich-730	1	1	biology	biology	NOUN
biomedich-730	1	2	,	,	PUNCT
biomedich-730	1	3	medicine	medicine	NOUN
biomedich-730	1	4	,	,	PUNCT
biomedich-730	1	5	&	&	CCONJ
biomedich-730	1	6	natural	natural	ADJ
biomedich-730	1	7	product	product	NOUN
biomedich-730	1	8	chemistry	chemistry	NOUN
biomedich-730	1	9	issn	issn	VERB
biomedich-730	1	10	2089	2089	NUM
biomedich-730	1	11	-	-	SYM
biomedich-730	1	12	6514	6514	NUM
biomedich-730	1	13	(	(	PUNCT
biomedich-730	1	14	paper	paper	NOUN
biomedich-730	1	15	)	)	PUNCT
biomedich-730	1	16	volume	volume	NOUN
biomedich-730	1	17	14	14	NUM
biomedich-730	1	18	,	,	PUNCT
biomedich-730	1	19	number	number	NOUN
biomedich-730	1	20	1	1	NUM
biomedich-730	1	21	,	,	PUNCT
biomedich-730	1	22	april	april	PROPN
biomedich-730	1	23	2025	2025	NUM
biomedich-730	1	24	|	|	ADV
biomedich-730	1	25	pages	page	NOUN
biomedich-730	1	26	:	:	PUNCT
biomedich-730	1	27	275	275	NUM
biomedich-730	1	28	-	-	SYM
biomedich-730	1	29	282	282	NUM
biomedich-730	1	30	|	|	ADV
biomedich-730	1	31	doi	doi	NOUN
biomedich-730	1	32	:	:	PUNCT
biomedich-730	1	33	10.14421	10.14421	NUM
biomedich-730	1	34	/	/	SYM
biomedich-730	1	35	biomedich.2025.141.275	biomedich.2025.141.275	VERB
biomedich-730	1	36	-	-	PUNCT
biomedich-730	1	37	282	282	NUM
biomedich-730	1	38	issn	issn	PROPN
biomedich-730	1	39	2540	2540	NUM
biomedich-730	1	40	-	-	SYM
biomedich-730	1	41	9328	9328	NUM
biomedich-730	1	42	(	(	PUNCT
biomedich-730	1	43	online	online	ADV
biomedich-730	1	44	)	)	PUNCT
biomedich-730	1	45	in	in	ADP
biomedich-730	1	46	silico	silico	NOUN
biomedich-730	1	47	analysis	analysis	NOUN
biomedich-730	1	48	of	of	ADP
biomedich-730	1	49	ocimum	ocimum	ADJ
biomedich-730	1	50	basilicum	basilicum	NOUN
biomedich-730	1	51	flavonoids	flavonoid	NOUN
biomedich-730	1	52	as	as	ADP
biomedich-730	1	53	natural	natural	ADJ
biomedich-730	1	54	antihypertensive	antihypertensive	ADJ
biomedich-730	1	55	agent	agent	NOUN
biomedich-730	1	56	on	on	ADP
biomedich-730	1	57	angiotensin	angiotensin	PROPN
biomedich-730	1	58	ii	ii	PROPN
biomedich-730	1	59	type-1	type-1	PROPN
biomedich-730	1	60	receptor	receptor	NOUN
biomedich-730	1	61	(	(	PUNCT
biomedich-730	1	62	at1r	at1r	ADV
biomedich-730	1	63	)	)	PUNCT
biomedich-730	1	64	amir	amir	PROPN
biomedich-730	1	65	thalib1	thalib1	PROPN
biomedich-730	1	66	,	,	PUNCT
biomedich-730	1	67	*	*	PROPN
biomedich-730	1	68	,	,	PUNCT
biomedich-730	1	69	irma	irma	PROPN
biomedich-730	1	70	putri	putri	PROPN
biomedich-730	1	71	damayanti2	damayanti2	PUNCT
biomedich-730	2	1	1department	1department	NUM
biomedich-730	2	2	of	of	ADP
biomedich-730	2	3	medicine	medicine	NOUN
biomedich-730	2	4	;	;	PUNCT
biomedich-730	3	1	2department	2department	NUM
biomedich-730	3	2	of	of	ADP
biomedich-730	3	3	herbal	herbal	ADJ
biomedich-730	3	4	medicine	medicine	NOUN
biomedich-730	3	5	,	,	PUNCT
biomedich-730	3	6	faculty	faculty	NOUN
biomedich-730	3	7	of	of	ADP
biomedich-730	3	8	medicine	medicine	NOUN
biomedich-730	3	9	;	;	PUNCT
biomedich-730	3	10	university	university	NOUN
biomedich-730	3	11	of	of	ADP
biomedich-730	3	12	muhammadiyah	muhammadiyah	NOUN
biomedich-730	3	13	purwokerto	purwokerto	NOUN
biomedich-730	3	14	,	,	PUNCT
biomedich-730	3	15	jl	jl	PROPN
biomedich-730	3	16	.	.	PUNCT
biomedich-730	4	1	kh	kh	PROPN
biomedich-730	4	2	.	.	PUNCT
biomedich-730	5	1	ahmad	ahmad	PROPN
biomedich-730	5	2	dahlan	dahlan	PROPN
biomedich-730	5	3	,	,	PUNCT
biomedich-730	5	4	purwokerto	purwokerto	NOUN
biomedich-730	5	5	53182	53182	NUM
biomedich-730	5	6	,	,	PUNCT
biomedich-730	5	7	tel	tel	PROPN
biomedich-730	5	8	.	.	PUNCT
biomedich-730	6	1	+62	+62	PROPN
biomedich-730	6	2	-	-	PUNCT
biomedich-730	6	3	856	856	NUM
biomedich-730	6	4	-	-	PUNCT
biomedich-730	6	5	2988	2988	NUM
biomedich-730	6	6	-	-	SYM
biomedich-730	6	7	092	092	NUM
biomedich-730	6	8	,	,	PUNCT
biomedich-730	6	9	indonesia	indonesia	PROPN
biomedich-730	6	10	.	.	PUNCT
biomedich-730	7	1	corresponding	correspond	VERB
biomedich-730	7	2	author	author	NOUN
biomedich-730	7	3	*	*	PUNCT
biomedich-730	7	4	amirthalib18@gmail.com	amirthalib18@gmail.com	X
biomedich-730	7	5	manuscript	manuscript	NOUN
biomedich-730	7	6	received	receive	VERB
biomedich-730	7	7	:	:	PUNCT
biomedich-730	7	8	28	28	NUM
biomedich-730	7	9	february	february	PROPN
biomedich-730	7	10	,	,	PUNCT
biomedich-730	7	11	2025	2025	NUM
biomedich-730	7	12	.	.	PUNCT
biomedich-730	8	1	revision	revision	NOUN
biomedich-730	8	2	accepted	accept	VERB
biomedich-730	8	3	:	:	PUNCT
biomedich-730	8	4	20	20	NUM
biomedich-730	8	5	may	may	NOUN
biomedich-730	8	6	,	,	PUNCT
biomedich-730	8	7	2025	2025	NUM
biomedich-730	8	8	.	.	PUNCT
biomedich-730	9	1	published	publish	VERB
biomedich-730	9	2	:	:	PUNCT
biomedich-730	9	3	24	24	NUM
biomedich-730	9	4	june	june	PROPN
biomedich-730	9	5	,	,	PUNCT
biomedich-730	9	6	2025	2025	NUM
biomedich-730	9	7	.	.	PUNCT
biomedich-730	10	1	abstract	abstract	ADV
biomedich-730	10	2	despite	despite	SCONJ
biomedich-730	10	3	the	the	DET
biomedich-730	10	4	efficacy	efficacy	NOUN
biomedich-730	10	5	of	of	ADP
biomedich-730	10	6	antihypertensive	antihypertensive	ADJ
biomedich-730	10	7	medications	medication	NOUN
biomedich-730	10	8	like	like	ADP
biomedich-730	10	9	arbs	arb	NOUN
biomedich-730	10	10	,	,	PUNCT
biomedich-730	10	11	their	their	PRON
biomedich-730	10	12	adverse	adverse	ADJ
biomedich-730	10	13	effects	effect	NOUN
biomedich-730	10	14	frequently	frequently	ADV
biomedich-730	10	15	result	result	VERB
biomedich-730	10	16	in	in	ADP
biomedich-730	10	17	suboptimal	suboptimal	ADJ
biomedich-730	10	18	adherence	adherence	NOUN
biomedich-730	10	19	.	.	PUNCT
biomedich-730	11	1	this	this	DET
biomedich-730	11	2	study	study	NOUN
biomedich-730	11	3	investigates	investigate	VERB
biomedich-730	11	4	the	the	DET
biomedich-730	11	5	efficacy	efficacy	NOUN
biomedich-730	11	6	of	of	ADP
biomedich-730	11	7	flavonoids	flavonoid	NOUN
biomedich-730	11	8	obtained	obtain	VERB
biomedich-730	11	9	from	from	ADP
biomedich-730	11	10	herbal	herbal	ADJ
biomedich-730	11	11	sources	source	NOUN
biomedich-730	11	12	as	as	ADP
biomedich-730	11	13	natural	natural	ADJ
biomedich-730	11	14	substitutes	substitute	NOUN
biomedich-730	11	15	for	for	ADP
biomedich-730	11	16	traditional	traditional	ADJ
biomedich-730	11	17	antihypertensive	antihypertensive	ADJ
biomedich-730	11	18	therapies	therapy	NOUN
biomedich-730	11	19	.	.	PUNCT
biomedich-730	12	1	this	this	DET
biomedich-730	12	2	study	study	NOUN
biomedich-730	12	3	employed	employ	VERB
biomedich-730	12	4	in	in	ADP
biomedich-730	12	5	silico	silico	NOUN
biomedich-730	12	6	molecular	molecular	ADJ
biomedich-730	12	7	docking	docking	NOUN
biomedich-730	12	8	to	to	PART
biomedich-730	12	9	examine	examine	VERB
biomedich-730	12	10	the	the	DET
biomedich-730	12	11	binding	bind	VERB
biomedich-730	12	12	affinity	affinity	NOUN
biomedich-730	12	13	of	of	ADP
biomedich-730	12	14	flavonoids	flavonoid	NOUN
biomedich-730	12	15	to	to	ADP
biomedich-730	12	16	the	the	DET
biomedich-730	12	17	angiotensin	angiotensin	NOUN
biomedich-730	12	18	ii	ii	PROPN
biomedich-730	12	19	type-1	type-1	PROPN
biomedich-730	12	20	receptor	receptor	NOUN
biomedich-730	12	21	(	(	PUNCT
biomedich-730	12	22	at1r	at1r	ADV
biomedich-730	12	23	)	)	PUNCT
biomedich-730	12	24	in	in	ADP
biomedich-730	12	25	comparison	comparison	NOUN
biomedich-730	12	26	to	to	ADP
biomedich-730	12	27	standard	standard	ADJ
biomedich-730	12	28	angiotensin	angiotensin	NOUN
biomedich-730	12	29	receptor	receptor	NOUN
biomedich-730	12	30	blockers	blocker	NOUN
biomedich-730	12	31	(	(	PUNCT
biomedich-730	12	32	arbs	arb	NOUN
biomedich-730	12	33	)	)	PUNCT
biomedich-730	12	34	,	,	PUNCT
biomedich-730	12	35	namely	namely	ADV
biomedich-730	12	36	eprosartan	eprosartan	ADJ
biomedich-730	12	37	,	,	PUNCT
biomedich-730	12	38	azilsartan	azilsartan	ADJ
biomedich-730	12	39	,	,	PUNCT
biomedich-730	12	40	irbesartan	irbesartan	PROPN
biomedich-730	12	41	,	,	PUNCT
biomedich-730	12	42	telmisartan	telmisartan	PROPN
biomedich-730	12	43	,	,	PUNCT
biomedich-730	12	44	valsartan	valsartan	PROPN
biomedich-730	12	45	,	,	PUNCT
biomedich-730	12	46	losartan	losartan	PROPN
biomedich-730	12	47	,	,	PUNCT
biomedich-730	12	48	olmesartan	olmesartan	PROPN
biomedich-730	12	49	,	,	PUNCT
biomedich-730	12	50	and	and	CCONJ
biomedich-730	12	51	candesartan	candesartan	PROPN
biomedich-730	12	52	.	.	PUNCT
biomedich-730	13	1	docking	dock	VERB
biomedich-730	13	2	analysis	analysis	NOUN
biomedich-730	13	3	indicated	indicate	VERB
biomedich-730	13	4	that	that	SCONJ
biomedich-730	13	5	the	the	DET
biomedich-730	13	6	flavonoids	flavonoid	NOUN
biomedich-730	13	7	exhibited	exhibit	VERB
biomedich-730	13	8	a	a	DET
biomedich-730	13	9	favorable	favorable	ADJ
biomedich-730	13	10	binding	bind	VERB
biomedich-730	13	11	affinity	affinity	NOUN
biomedich-730	13	12	of	of	ADP
biomedich-730	13	13	-8.8	-8.8	PROPN
biomedich-730	13	14	kcal	kcal	PROPN
biomedich-730	13	15	/	/	SYM
biomedich-730	13	16	mol	mol	NOUN
biomedich-730	13	17	for	for	ADP
biomedich-730	13	18	at1r	at1r	PROPN
biomedich-730	13	19	.	.	PUNCT
biomedich-730	14	1	moreover	moreover	ADV
biomedich-730	14	2	,	,	PUNCT
biomedich-730	14	3	adme	adme	NOUN
biomedich-730	14	4	and	and	CCONJ
biomedich-730	14	5	toxicity	toxicity	NOUN
biomedich-730	14	6	assessments	assessment	NOUN
biomedich-730	14	7	indicated	indicate	VERB
biomedich-730	14	8	that	that	SCONJ
biomedich-730	14	9	flavonoids	flavonoid	NOUN
biomedich-730	14	10	exhibit	exhibit	VERB
biomedich-730	14	11	advantageous	advantageous	ADJ
biomedich-730	14	12	pharmacokinetics	pharmacokinetic	NOUN
biomedich-730	14	13	and	and	CCONJ
biomedich-730	14	14	minimal	minimal	ADJ
biomedich-730	14	15	toxicity	toxicity	NOUN
biomedich-730	14	16	,	,	PUNCT
biomedich-730	14	17	with	with	ADP
biomedich-730	14	18	no	no	DET
biomedich-730	14	19	significant	significant	ADJ
biomedich-730	14	20	adverse	adverse	ADJ
biomedich-730	14	21	interactions	interaction	NOUN
biomedich-730	14	22	anticipated	anticipate	VERB
biomedich-730	14	23	with	with	ADP
biomedich-730	14	24	primary	primary	ADJ
biomedich-730	14	25	metabolic	metabolic	NOUN
biomedich-730	14	26	enzymes	enzyme	NOUN
biomedich-730	14	27	.	.	PUNCT
biomedich-730	15	1	the	the	DET
biomedich-730	15	2	structural	structural	ADJ
biomedich-730	15	3	validation	validation	NOUN
biomedich-730	15	4	,	,	PUNCT
biomedich-730	15	5	encompassing	encompass	VERB
biomedich-730	15	6	ramachandran	ramachandran	NOUN
biomedich-730	15	7	plots	plot	NOUN
biomedich-730	15	8	and	and	CCONJ
biomedich-730	15	9	errat	errat	NOUN
biomedich-730	15	10	analysis	analysis	NOUN
biomedich-730	15	11	,	,	PUNCT
biomedich-730	15	12	affirmed	affirm	VERB
biomedich-730	15	13	the	the	DET
biomedich-730	15	14	reliability	reliability	NOUN
biomedich-730	15	15	of	of	ADP
biomedich-730	15	16	the	the	DET
biomedich-730	15	17	modeled	model	VERB
biomedich-730	15	18	at1r	at1r	PROPN
biomedich-730	15	19	protein	protein	NOUN
biomedich-730	15	20	,	,	PUNCT
biomedich-730	15	21	achieving	achieve	VERB
biomedich-730	15	22	a	a	DET
biomedich-730	15	23	quality	quality	NOUN
biomedich-730	15	24	score	score	NOUN
biomedich-730	15	25	of	of	ADP
biomedich-730	15	26	97.13	97.13	NUM
biomedich-730	15	27	%	%	NOUN
biomedich-730	15	28	.	.	PUNCT
biomedich-730	16	1	this	this	DET
biomedich-730	16	2	study	study	NOUN
biomedich-730	16	3	concludes	conclude	VERB
biomedich-730	16	4	that	that	SCONJ
biomedich-730	16	5	flavonoids	flavonoid	NOUN
biomedich-730	16	6	derived	derive	VERB
biomedich-730	16	7	from	from	ADP
biomedich-730	16	8	ocimum	ocimum	PROPN
biomedich-730	16	9	basilicum	basilicum	PROPN
biomedich-730	16	10	exhibit	exhibit	VERB
biomedich-730	16	11	significant	significant	ADJ
biomedich-730	16	12	potential	potential	NOUN
biomedich-730	16	13	as	as	ADP
biomedich-730	16	14	natural	natural	ADJ
biomedich-730	16	15	antihypertensive	antihypertensive	ADJ
biomedich-730	16	16	agents	agent	NOUN
biomedich-730	16	17	.	.	PUNCT
biomedich-730	17	1	these	these	DET
biomedich-730	17	2	findings	finding	NOUN
biomedich-730	17	3	may	may	AUX
biomedich-730	17	4	facilitate	facilitate	VERB
biomedich-730	17	5	the	the	DET
biomedich-730	17	6	development	development	NOUN
biomedich-730	17	7	of	of	ADP
biomedich-730	17	8	plant	plant	NOUN
biomedich-730	17	9	-	-	PUNCT
biomedich-730	17	10	based	base	VERB
biomedich-730	17	11	therapies	therapy	NOUN
biomedich-730	17	12	with	with	ADP
biomedich-730	17	13	minimal	minimal	ADJ
biomedich-730	17	14	adverse	adverse	ADJ
biomedich-730	17	15	effects	effect	NOUN
biomedich-730	17	16	,	,	PUNCT
biomedich-730	17	17	enhance	enhance	VERB
biomedich-730	17	18	treatment	treatment	NOUN
biomedich-730	17	19	adherence	adherence	NOUN
biomedich-730	17	20	,	,	PUNCT
biomedich-730	17	21	and	and	CCONJ
biomedich-730	17	22	improve	improve	VERB
biomedich-730	17	23	the	the	DET
biomedich-730	17	24	pharmacological	pharmacological	ADJ
biomedich-730	17	25	options	option	NOUN
biomedich-730	17	26	for	for	ADP
biomedich-730	17	27	managing	manage	VERB
biomedich-730	17	28	hypertension	hypertension	NOUN
biomedich-730	17	29	.	.	PUNCT
biomedich-730	18	1	keywords	keyword	NOUN
biomedich-730	18	2	:	:	PUNCT
biomedich-730	18	3	adme	adme	NOUN
biomedich-730	18	4	;	;	PUNCT
biomedich-730	18	5	angiotensin	angiotensin	NOUN
biomedich-730	18	6	ii	ii	PROPN
biomedich-730	18	7	receptor	receptor	NOUN
biomedich-730	18	8	;	;	PUNCT
biomedich-730	18	9	flavonoids	flavonoid	NOUN
biomedich-730	18	10	;	;	PUNCT
biomedich-730	18	11	molecular	molecular	ADJ
biomedich-730	18	12	docking	docking	NOUN
biomedich-730	18	13	;	;	PUNCT
biomedich-730	18	14	ocimum	ocimum	ADJ
biomedich-730	18	15	basilicum	basilicum	PROPN
biomedich-730	18	16	.	.	PUNCT
biomedich-730	19	1	abbreviations	abbreviation	NOUN
biomedich-730	19	2	:	:	PUNCT
biomedich-730	19	3	arbs	arb	NOUN
biomedich-730	19	4	:	:	PUNCT
biomedich-730	19	5	angiotensin	angiotensin	NOUN
biomedich-730	19	6	receptor	receptor	NOUN
biomedich-730	19	7	blockers	blocker	NOUN
biomedich-730	19	8	;	;	PUNCT
biomedich-730	19	9	ace	ace	NOUN
biomedich-730	19	10	:	:	PUNCT
biomedich-730	19	11	angiotensin	angiotensin	NOUN
biomedich-730	19	12	-	-	PUNCT
biomedich-730	19	13	converting	convert	VERB
biomedich-730	19	14	enzyme	enzyme	NOUN
biomedich-730	19	15	;	;	PUNCT
biomedich-730	19	16	at1r	at1r	ADV
biomedich-730	19	17	:	:	PUNCT
biomedich-730	19	18	angiotensin	angiotensin	PROPN
biomedich-730	19	19	ii	ii	PROPN
biomedich-730	19	20	type-1	type-1	NUM
biomedich-730	19	21	receptor	receptor	NOUN
biomedich-730	19	22	;	;	PUNCT
biomedich-730	19	23	adme	adme	NOUN
biomedich-730	19	24	:	:	PUNCT
biomedich-730	19	25	absorption	absorption	NOUN
biomedich-730	19	26	,	,	PUNCT
biomedich-730	19	27	distribution	distribution	NOUN
biomedich-730	19	28	,	,	PUNCT
biomedich-730	19	29	metabolism	metabolism	NOUN
biomedich-730	19	30	,	,	PUNCT
biomedich-730	19	31	and	and	CCONJ
biomedich-730	19	32	excretion	excretion	NOUN
biomedich-730	19	33	;	;	PUNCT
biomedich-730	19	34	vdss	vdss	ADV
biomedich-730	19	35	:	:	PUNCT
biomedich-730	19	36	volume	volume	NOUN
biomedich-730	19	37	of	of	ADP
biomedich-730	19	38	steady	steady	ADJ
biomedich-730	19	39	-	-	PUNCT
biomedich-730	19	40	state	state	NOUN
biomedich-730	19	41	distribution	distribution	NOUN
biomedich-730	19	42	.	.	PUNCT
biomedich-730	20	1	introduction	introduction	NOUN
biomedich-730	20	2	hypertension	hypertension	NOUN
biomedich-730	20	3	is	be	AUX
biomedich-730	20	4	a	a	DET
biomedich-730	20	5	multifactorial	multifactorial	ADJ
biomedich-730	20	6	condition	condition	NOUN
biomedich-730	20	7	and	and	CCONJ
biomedich-730	20	8	is	be	AUX
biomedich-730	20	9	an	an	DET
biomedich-730	20	10	important	important	ADJ
biomedich-730	20	11	risk	risk	NOUN
biomedich-730	20	12	factor	factor	NOUN
biomedich-730	20	13	for	for	ADP
biomedich-730	20	14	stroke	stroke	NOUN
biomedich-730	20	15	and	and	CCONJ
biomedich-730	20	16	cardiovascular	cardiovascular	ADJ
biomedich-730	20	17	disease	disease	NOUN
biomedich-730	20	18	(	(	PUNCT
biomedich-730	20	19	raddaoui	raddaoui	ADP
biomedich-730	20	20	et	et	PROPN
biomedich-730	20	21	al	al	PROPN
biomedich-730	20	22	.	.	PROPN
biomedich-730	20	23	,	,	PUNCT
biomedich-730	20	24	2024	2024	NUM
biomedich-730	20	25	)	)	PUNCT
biomedich-730	20	26	.	.	PUNCT
biomedich-730	21	1	approximately	approximately	ADV
biomedich-730	21	2	33	33	NUM
biomedich-730	21	3	%	%	NOUN
biomedich-730	21	4	of	of	ADP
biomedich-730	21	5	the	the	DET
biomedich-730	21	6	global	global	ADJ
biomedich-730	21	7	population	population	NOUN
biomedich-730	21	8	of	of	ADP
biomedich-730	21	9	8	8	NUM
biomedich-730	21	10	billion	billion	NUM
biomedich-730	21	11	individuals	individual	NOUN
biomedich-730	21	12	suffers	suffer	VERB
biomedich-730	21	13	from	from	ADP
biomedich-730	21	14	hypertension	hypertension	NOUN
biomedich-730	21	15	.	.	PUNCT
biomedich-730	22	1	lifestyle	lifestyle	PROPN
biomedich-730	22	2	modifications	modification	NOUN
biomedich-730	22	3	are	be	AUX
biomedich-730	22	4	essential	essential	ADJ
biomedich-730	22	5	for	for	ADP
biomedich-730	22	6	the	the	DET
biomedich-730	22	7	prevention	prevention	NOUN
biomedich-730	22	8	and	and	CCONJ
biomedich-730	22	9	management	management	NOUN
biomedich-730	22	10	of	of	ADP
biomedich-730	22	11	hypertension	hypertension	NOUN
biomedich-730	22	12	,	,	PUNCT
biomedich-730	22	13	and	and	CCONJ
biomedich-730	22	14	both	both	CCONJ
biomedich-730	22	15	governmental	governmental	ADJ
biomedich-730	22	16	and	and	CCONJ
biomedich-730	22	17	industrial	industrial	ADJ
biomedich-730	22	18	support	support	NOUN
biomedich-730	22	19	are	be	AUX
biomedich-730	22	20	crucial	crucial	ADJ
biomedich-730	22	21	for	for	ADP
biomedich-730	22	22	the	the	DET
biomedich-730	22	23	endorsement	endorsement	NOUN
biomedich-730	22	24	and	and	CCONJ
biomedich-730	22	25	implementation	implementation	NOUN
biomedich-730	22	26	of	of	ADP
biomedich-730	22	27	these	these	DET
biomedich-730	22	28	modifications	modification	NOUN
biomedich-730	22	29	(	(	PUNCT
biomedich-730	22	30	charchar	charchar	PROPN
biomedich-730	22	31	et	et	PROPN
biomedich-730	22	32	al	al	PROPN
biomedich-730	22	33	.	.	PROPN
biomedich-730	22	34	,	,	PUNCT
biomedich-730	22	35	2024	2024	NUM
biomedich-730	22	36	)	)	PUNCT
biomedich-730	22	37	.	.	PUNCT
biomedich-730	23	1	angiotensin	angiotensin	PROPN
biomedich-730	23	2	ii	ii	PROPN
biomedich-730	23	3	type-1	type-1	PROPN
biomedich-730	23	4	receptor	receptor	NOUN
biomedich-730	23	5	blockers	blocker	NOUN
biomedich-730	23	6	(	(	PUNCT
biomedich-730	23	7	arbs	arb	NOUN
biomedich-730	23	8	)	)	PUNCT
biomedich-730	23	9	are	be	AUX
biomedich-730	23	10	extensively	extensively	ADV
biomedich-730	23	11	prescribed	prescribe	VERB
biomedich-730	23	12	medications	medication	NOUN
biomedich-730	23	13	for	for	ADP
biomedich-730	23	14	managing	manage	VERB
biomedich-730	23	15	arterial	arterial	ADJ
biomedich-730	23	16	hypertension	hypertension	NOUN
biomedich-730	23	17	,	,	PUNCT
biomedich-730	23	18	heart	heart	NOUN
biomedich-730	23	19	failure	failure	NOUN
biomedich-730	23	20	,	,	PUNCT
biomedich-730	23	21	and	and	CCONJ
biomedich-730	23	22	chronic	chronic	ADJ
biomedich-730	23	23	kidney	kidney	NOUN
biomedich-730	23	24	disease	disease	NOUN
biomedich-730	23	25	(	(	PUNCT
biomedich-730	23	26	de	de	X
biomedich-730	23	27	vries	vries	PROPN
biomedich-730	23	28	,	,	PUNCT
biomedich-730	23	29	2020	2020	NUM
biomedich-730	23	30	)	)	PUNCT
biomedich-730	23	31	.	.	PUNCT
biomedich-730	24	1	nonetheless	nonetheless	ADV
biomedich-730	24	2	,	,	PUNCT
biomedich-730	24	3	antihypertensive	antihypertensive	ADJ
biomedich-730	24	4	medications	medication	NOUN
biomedich-730	24	5	continue	continue	VERB
biomedich-730	24	6	to	to	PART
biomedich-730	24	7	exhibit	exhibit	VERB
biomedich-730	24	8	numerous	numerous	ADJ
biomedich-730	24	9	side	side	NOUN
biomedich-730	24	10	effects	effect	NOUN
biomedich-730	24	11	,	,	PUNCT
biomedich-730	24	12	necessitating	necessitate	VERB
biomedich-730	24	13	the	the	DET
biomedich-730	24	14	substitution	substitution	NOUN
biomedich-730	24	15	of	of	ADP
biomedich-730	24	16	these	these	DET
biomedich-730	24	17	drugs	drug	NOUN
biomedich-730	24	18	with	with	ADP
biomedich-730	24	19	alternatives	alternative	NOUN
biomedich-730	24	20	that	that	PRON
biomedich-730	24	21	possess	possess	VERB
biomedich-730	24	22	minimal	minimal	ADJ
biomedich-730	24	23	adverse	adverse	ADJ
biomedich-730	24	24	effects	effect	NOUN
biomedich-730	24	25	.	.	PUNCT
biomedich-730	25	1	previous	previous	ADJ
biomedich-730	25	2	research	research	NOUN
biomedich-730	25	3	by	by	ADP
biomedich-730	25	4	ruijun	ruijun	PROPN
biomedich-730	25	5	chen	chen	PROPN
biomedich-730	25	6	et	et	PROPN
biomedich-730	25	7	al	al	PROPN
biomedich-730	25	8	(	(	PUNCT
biomedich-730	25	9	2021	2021	NUM
biomedich-730	25	10	)	)	PUNCT
biomedich-730	25	11	examining	examine	VERB
biomedich-730	25	12	the	the	DET
biomedich-730	25	13	side	side	NOUN
biomedich-730	25	14	effects	effect	NOUN
biomedich-730	25	15	of	of	ADP
biomedich-730	25	16	anti	anti	ADJ
biomedich-730	25	17	-	-	ADJ
biomedich-730	25	18	hypertensive	hypertensive	ADJ
biomedich-730	25	19	medications	medication	NOUN
biomedich-730	25	20	,	,	PUNCT
biomedich-730	25	21	particularly	particularly	ADV
biomedich-730	25	22	ace	ace	VERB
biomedich-730	25	23	inhibitors	inhibitor	NOUN
biomedich-730	25	24	and	and	CCONJ
biomedich-730	25	25	arbs	arb	NOUN
biomedich-730	25	26	,	,	PUNCT
biomedich-730	25	27	indicates	indicate	VERB
biomedich-730	25	28	that	that	SCONJ
biomedich-730	25	29	there	there	PRON
biomedich-730	25	30	is	be	VERB
biomedich-730	25	31	no	no	DET
biomedich-730	25	32	significant	significant	ADJ
biomedich-730	25	33	difference	difference	NOUN
biomedich-730	25	34	between	between	ADP
biomedich-730	25	35	these	these	DET
biomedich-730	25	36	two	two	NUM
biomedich-730	25	37	classes	class	NOUN
biomedich-730	25	38	regarding	regard	VERB
biomedich-730	25	39	the	the	DET
biomedich-730	25	40	risk	risk	NOUN
biomedich-730	25	41	of	of	ADP
biomedich-730	25	42	acute	acute	ADJ
biomedich-730	25	43	myocardial	myocardial	ADJ
biomedich-730	25	44	infarction	infarction	NOUN
biomedich-730	25	45	,	,	PUNCT
biomedich-730	25	46	heart	heart	NOUN
biomedich-730	25	47	failure	failure	NOUN
biomedich-730	25	48	,	,	PUNCT
biomedich-730	25	49	stroke	stroke	NOUN
biomedich-730	25	50	,	,	PUNCT
biomedich-730	25	51	or	or	CCONJ
biomedich-730	25	52	composite	composite	ADJ
biomedich-730	25	53	cardiovascular	cardiovascular	ADJ
biomedich-730	25	54	events	event	NOUN
biomedich-730	25	55	(	(	PUNCT
biomedich-730	25	56	chen	chen	PROPN
biomedich-730	25	57	et	et	PROPN
biomedich-730	25	58	al	al	PROPN
biomedich-730	25	59	.	.	PROPN
biomedich-730	25	60	,	,	PUNCT
biomedich-730	25	61	2021	2021	NUM
biomedich-730	25	62	)	)	PUNCT
biomedich-730	25	63	.	.	PUNCT
biomedich-730	26	1	medicinal	medicinal	ADJ
biomedich-730	26	2	herbs	herb	NOUN
biomedich-730	26	3	remain	remain	VERB
biomedich-730	26	4	a	a	DET
biomedich-730	26	5	viable	viable	ADJ
biomedich-730	26	6	alternative	alternative	ADJ
biomedich-730	26	7	treatment	treatment	NOUN
biomedich-730	26	8	for	for	ADP
biomedich-730	26	9	various	various	ADJ
biomedich-730	26	10	diseases	disease	NOUN
biomedich-730	26	11	,	,	PUNCT
biomedich-730	26	12	including	include	VERB
biomedich-730	26	13	cardiovascular	cardiovascular	ADJ
biomedich-730	26	14	diseases	disease	NOUN
biomedich-730	26	15	(	(	PUNCT
biomedich-730	26	16	cvds	cvds	PROPN
biomedich-730	26	17	)	)	PUNCT
biomedich-730	26	18	.	.	PUNCT
biomedich-730	27	1	there	there	PRON
biomedich-730	27	2	is	be	VERB
biomedich-730	27	3	an	an	DET
biomedich-730	27	4	unparalleled	unparalleled	ADJ
biomedich-730	27	5	impetus	impetus	NOUN
biomedich-730	27	6	for	for	ADP
biomedich-730	27	7	the	the	DET
biomedich-730	27	8	utilization	utilization	NOUN
biomedich-730	27	9	of	of	ADP
biomedich-730	27	10	herbal	herbal	ADJ
biomedich-730	27	11	preparations	preparation	NOUN
biomedich-730	27	12	in	in	ADP
biomedich-730	27	13	contemporary	contemporary	ADJ
biomedich-730	27	14	medicinal	medicinal	ADJ
biomedich-730	27	15	systems	system	NOUN
biomedich-730	27	16	,	,	PUNCT
biomedich-730	27	17	this	this	DET
biomedich-730	27	18	initiative	initiative	NOUN
biomedich-730	27	19	is	be	AUX
biomedich-730	27	20	driven	drive	VERB
biomedich-730	27	21	by	by	ADP
biomedich-730	27	22	multiple	multiple	ADJ
biomedich-730	27	23	factors	factor	NOUN
biomedich-730	27	24	,	,	PUNCT
biomedich-730	27	25	foremost	foremost	ADV
biomedich-730	27	26	among	among	ADP
biomedich-730	27	27	them	they	PRON
biomedich-730	27	28	being	be	AUX
biomedich-730	27	29	their	their	PRON
biomedich-730	27	30	cost	cost	NOUN
biomedich-730	27	31	therapeutic	therapeutic	ADJ
biomedich-730	27	32	potential	potential	ADJ
biomedich-730	27	33	relative	relative	NOUN
biomedich-730	27	34	to	to	ADP
biomedich-730	27	35	conventional	conventional	ADJ
biomedich-730	27	36	modern	modern	ADJ
biomedich-730	27	37	treatments	treatment	NOUN
biomedich-730	27	38	and	and	CCONJ
biomedich-730	27	39	the	the	DET
biomedich-730	27	40	general	general	ADJ
biomedich-730	27	41	understanding	understanding	NOUN
biomedich-730	27	42	of	of	ADP
biomedich-730	27	43	their	their	PRON
biomedich-730	27	44	safety	safety	NOUN
biomedich-730	27	45	(	(	PUNCT
biomedich-730	27	46	shaito	shaito	NOUN
biomedich-730	27	47	et	et	PROPN
biomedich-730	27	48	al	al	PROPN
biomedich-730	27	49	.	.	PROPN
biomedich-730	27	50	,	,	PUNCT
biomedich-730	27	51	2020	2020	NUM
biomedich-730	27	52	)	)	PUNCT
biomedich-730	27	53	.	.	PUNCT
biomedich-730	28	1	the	the	DET
biomedich-730	28	2	side	side	NOUN
biomedich-730	28	3	effects	effect	NOUN
biomedich-730	28	4	associated	associate	VERB
biomedich-730	28	5	with	with	ADP
biomedich-730	28	6	antihypertensive	antihypertensive	ADJ
biomedich-730	28	7	medications	medication	NOUN
biomedich-730	28	8	,	,	PUNCT
biomedich-730	28	9	including	include	VERB
biomedich-730	28	10	fatigue	fatigue	NOUN
biomedich-730	28	11	,	,	PUNCT
biomedich-730	28	12	myalgia	myalgia	NOUN
biomedich-730	28	13	,	,	PUNCT
biomedich-730	28	14	and	and	CCONJ
biomedich-730	28	15	insomnia	insomnia	NOUN
biomedich-730	28	16	,	,	PUNCT
biomedich-730	28	17	frequently	frequently	ADV
biomedich-730	28	18	serve	serve	VERB
biomedich-730	28	19	as	as	ADP
biomedich-730	28	20	a	a	DET
biomedich-730	28	21	substantial	substantial	ADJ
biomedich-730	28	22	predictor	predictor	NOUN
biomedich-730	28	23	of	of	ADP
biomedich-730	28	24	inadequate	inadequate	ADJ
biomedich-730	28	25	adherence	adherence	NOUN
biomedich-730	28	26	to	to	ADP
biomedich-730	28	27	treatment	treatment	NOUN
biomedich-730	28	28	(	(	PUNCT
biomedich-730	28	29	mitkova	mitkova	NOUN
biomedich-730	28	30	et	et	NOUN
biomedich-730	28	31	al	al	PROPN
biomedich-730	28	32	.	.	PROPN
biomedich-730	28	33	,	,	PUNCT
biomedich-730	28	34	2024	2024	NUM
biomedich-730	28	35	)	)	PUNCT
biomedich-730	28	36	.	.	PUNCT
biomedich-730	29	1	consequently	consequently	ADV
biomedich-730	29	2	,	,	PUNCT
biomedich-730	29	3	alternative	alternative	ADJ
biomedich-730	29	4	medicine	medicine	NOUN
biomedich-730	29	5	,	,	PUNCT
biomedich-730	29	6	specifically	specifically	ADV
biomedich-730	29	7	herbs	herb	NOUN
biomedich-730	29	8	,	,	PUNCT
biomedich-730	29	9	is	be	AUX
biomedich-730	29	10	regarded	regard	VERB
biomedich-730	29	11	as	as	ADP
biomedich-730	29	12	a	a	DET
biomedich-730	29	13	traditional	traditional	ADJ
biomedich-730	29	14	treatment	treatment	NOUN
biomedich-730	29	15	that	that	PRON
biomedich-730	29	16	may	may	AUX
biomedich-730	29	17	support	support	VERB
biomedich-730	29	18	or	or	CCONJ
biomedich-730	29	19	replace	replace	VERB
biomedich-730	29	20	conventional	conventional	ADJ
biomedich-730	29	21	medicine	medicine	NOUN
biomedich-730	29	22	.	.	PUNCT
biomedich-730	30	1	flavonoids	flavonoid	NOUN
biomedich-730	30	2	are	be	AUX
biomedich-730	30	3	small	small	ADJ
biomedich-730	30	4	molecular	molecular	ADJ
biomedich-730	30	5	secondary	secondary	ADJ
biomedich-730	30	6	metabolites	metabolite	NOUN
biomedich-730	30	7	produced	produce	VERB
biomedich-730	30	8	by	by	ADP
biomedich-730	30	9	plants	plant	NOUN
biomedich-730	30	10	that	that	PRON
biomedich-730	30	11	exhibit	exhibit	VERB
biomedich-730	30	12	diverse	diverse	ADJ
biomedich-730	30	13	biological	biological	ADJ
biomedich-730	30	14	activities	activity	NOUN
biomedich-730	30	15	(	(	PUNCT
biomedich-730	30	16	mierziak	mierziak	PROPN
biomedich-730	30	17	et	et	PROPN
biomedich-730	30	18	al	al	PROPN
biomedich-730	30	19	.	.	PROPN
biomedich-730	30	20	,	,	PUNCT
biomedich-730	30	21	2014	2014	NUM
biomedich-730	30	22	)	)	PUNCT
biomedich-730	30	23	.	.	PUNCT
biomedich-730	31	1	flavonoids	flavonoid	NOUN
biomedich-730	32	1	https://doi.org/10.14421/biomedich.2025.141.275-282	https://doi.org/10.14421/biomedich.2025.141.275-282	SYM
biomedich-730	32	2	276	276	NUM
biomedich-730	32	3	biology	biology	NOUN
biomedich-730	32	4	,	,	PUNCT
biomedich-730	32	5	medicine	medicine	NOUN
biomedich-730	32	6	,	,	PUNCT
biomedich-730	32	7	&	&	CCONJ
biomedich-730	32	8	natural	natural	ADJ
biomedich-730	32	9	product	product	NOUN
biomedich-730	32	10	chemistry	chemistry	NOUN
biomedich-730	32	11	14	14	NUM
biomedich-730	32	12	(	(	PUNCT
biomedich-730	32	13	1	1	NUM
biomedich-730	32	14	)	)	PUNCT
biomedich-730	32	15	,	,	PUNCT
biomedich-730	32	16	2025	2025	NUM
biomedich-730	32	17	:	:	PUNCT
biomedich-730	32	18	275	275	NUM
biomedich-730	32	19	-	-	SYM
biomedich-730	32	20	282	282	NUM
biomedich-730	32	21	are	be	AUX
biomedich-730	32	22	prevalent	prevalent	ADJ
biomedich-730	32	23	in	in	ADP
biomedich-730	32	24	numerous	numerous	ADJ
biomedich-730	32	25	plant	plant	NOUN
biomedich-730	32	26	species	specie	NOUN
biomedich-730	32	27	(	(	PUNCT
biomedich-730	32	28	ysrafil	ysrafil	PROPN
biomedich-730	32	29	et	et	PROPN
biomedich-730	32	30	al	al	PROPN
biomedich-730	32	31	.	.	PROPN
biomedich-730	32	32	,	,	PUNCT
biomedich-730	32	33	2023	2023	NUM
biomedich-730	32	34	)	)	PUNCT
biomedich-730	32	35	.	.	PUNCT
biomedich-730	33	1	flavonoids	flavonoid	NOUN
biomedich-730	33	2	are	be	AUX
biomedich-730	33	3	a	a	DET
biomedich-730	33	4	prevalent	prevalent	ADJ
biomedich-730	33	5	and	and	CCONJ
biomedich-730	33	6	extensive	extensive	ADJ
biomedich-730	33	7	category	category	NOUN
biomedich-730	33	8	of	of	ADP
biomedich-730	33	9	plant	plant	NOUN
biomedich-730	33	10	secondary	secondary	ADJ
biomedich-730	33	11	metabolites	metabolite	NOUN
biomedich-730	33	12	characterized	characterize	VERB
biomedich-730	33	13	by	by	ADP
biomedich-730	33	14	hydroxylated	hydroxylated	ADJ
biomedich-730	33	15	phenyl	phenyl	NOUN
biomedich-730	33	16	rings	ring	NOUN
biomedich-730	33	17	,	,	PUNCT
biomedich-730	33	18	encompassing	encompass	VERB
biomedich-730	33	19	flavones	flavone	NOUN
biomedich-730	33	20	,	,	PUNCT
biomedich-730	33	21	catechins	catechin	NOUN
biomedich-730	33	22	,	,	PUNCT
biomedich-730	33	23	and	and	CCONJ
biomedich-730	33	24	anthocyanins	anthocyanin	NOUN
biomedich-730	33	25	.	.	PUNCT
biomedich-730	34	1	a	a	DET
biomedich-730	34	2	diverse	diverse	ADJ
biomedich-730	34	3	array	array	NOUN
biomedich-730	34	4	of	of	ADP
biomedich-730	34	5	hydroxylation	hydroxylation	NOUN
biomedich-730	34	6	,	,	PUNCT
biomedich-730	34	7	methoxylation	methoxylation	NOUN
biomedich-730	34	8	,	,	PUNCT
biomedich-730	34	9	glycosylation	glycosylation	NOUN
biomedich-730	34	10	,	,	PUNCT
biomedich-730	34	11	and	and	CCONJ
biomedich-730	34	12	oligomerization	oligomerization	NOUN
biomedich-730	34	13	patterns	pattern	NOUN
biomedich-730	34	14	has	have	AUX
biomedich-730	34	15	been	be	AUX
biomedich-730	34	16	documented	document	VERB
biomedich-730	34	17	for	for	ADP
biomedich-730	34	18	this	this	DET
biomedich-730	34	19	class	class	NOUN
biomedich-730	34	20	of	of	ADP
biomedich-730	34	21	compounds	compound	NOUN
biomedich-730	34	22	,	,	PUNCT
biomedich-730	34	23	with	with	ADP
biomedich-730	34	24	thousands	thousand	NOUN
biomedich-730	34	25	of	of	ADP
biomedich-730	34	26	distinct	distinct	ADJ
biomedich-730	34	27	polyphenol	polyphenol	NOUN
biomedich-730	34	28	structures	structure	NOUN
biomedich-730	34	29	reported	report	VERB
biomedich-730	34	30	in	in	ADP
biomedich-730	34	31	the	the	DET
biomedich-730	34	32	literature	literature	NOUN
biomedich-730	34	33	.	.	PUNCT
biomedich-730	35	1	polyphenols	polyphenol	NOUN
biomedich-730	35	2	captivate	captivate	VERB
biomedich-730	35	3	the	the	DET
biomedich-730	35	4	scientific	scientific	ADJ
biomedich-730	35	5	community	community	NOUN
biomedich-730	35	6	owing	owe	VERB
biomedich-730	35	7	to	to	ADP
biomedich-730	35	8	their	their	PRON
biomedich-730	35	9	diverse	diverse	ADJ
biomedich-730	35	10	biological	biological	ADJ
biomedich-730	35	11	activities	activity	NOUN
biomedich-730	35	12	,	,	PUNCT
biomedich-730	35	13	including	include	VERB
biomedich-730	35	14	advantages	advantage	NOUN
biomedich-730	35	15	for	for	ADP
biomedich-730	35	16	cardiovascular	cardiovascular	ADJ
biomedich-730	35	17	health	health	NOUN
biomedich-730	35	18	(	(	PUNCT
biomedich-730	35	19	joyner	joyner	NOUN
biomedich-730	35	20	,	,	PUNCT
biomedich-730	35	21	2021	2021	NUM
biomedich-730	35	22	)	)	PUNCT
biomedich-730	35	23	.	.	PUNCT
biomedich-730	36	1	hypertension	hypertension	NOUN
biomedich-730	36	2	induces	induce	VERB
biomedich-730	36	3	oxidative	oxidative	ADJ
biomedich-730	36	4	stress	stress	NOUN
biomedich-730	36	5	,	,	PUNCT
biomedich-730	36	6	resulting	result	VERB
biomedich-730	36	7	in	in	ADP
biomedich-730	36	8	vasoconstriction	vasoconstriction	NOUN
biomedich-730	36	9	(	(	PUNCT
biomedich-730	36	10	matsubara	matsubara	NOUN
biomedich-730	36	11	,	,	PUNCT
biomedich-730	36	12	1998	1998	NUM
biomedich-730	36	13	)	)	PUNCT
biomedich-730	36	14	.	.	PUNCT
biomedich-730	37	1	flavonoids	flavonoid	NOUN
biomedich-730	37	2	can	can	AUX
biomedich-730	37	3	induce	induce	VERB
biomedich-730	37	4	vasodilation	vasodilation	NOUN
biomedich-730	37	5	by	by	ADP
biomedich-730	37	6	enhancing	enhance	VERB
biomedich-730	37	7	nitric	nitric	ADJ
biomedich-730	37	8	oxide	oxide	NOUN
biomedich-730	37	9	(	(	PUNCT
biomedich-730	37	10	no	no	NOUN
biomedich-730	37	11	)	)	PUNCT
biomedich-730	37	12	activity	activity	NOUN
biomedich-730	37	13	in	in	ADP
biomedich-730	37	14	endothelial	endothelial	ADJ
biomedich-730	37	15	cells	cell	NOUN
biomedich-730	37	16	.	.	PUNCT
biomedich-730	38	1	these	these	DET
biomedich-730	38	2	flavonoids	flavonoid	NOUN
biomedich-730	38	3	may	may	AUX
biomedich-730	38	4	inhibit	inhibit	VERB
biomedich-730	38	5	at1r	at1r	ADV
biomedich-730	38	6	;	;	PUNCT
biomedich-730	38	7	however	however	ADV
biomedich-730	38	8	,	,	PUNCT
biomedich-730	38	9	their	their	PRON
biomedich-730	38	10	precise	precise	ADJ
biomedich-730	38	11	affinity	affinity	NOUN
biomedich-730	38	12	and	and	CCONJ
biomedich-730	38	13	interaction	interaction	NOUN
biomedich-730	38	14	with	with	ADP
biomedich-730	38	15	at1r	at1r	PROPN
biomedich-730	38	16	remain	remain	VERB
biomedich-730	38	17	undetermined	undetermined	ADJ
biomedich-730	38	18	.	.	PUNCT
biomedich-730	39	1	at1r	at1r	PROPN
biomedich-730	39	2	is	be	AUX
biomedich-730	39	3	located	locate	VERB
biomedich-730	39	4	in	in	ADP
biomedich-730	39	5	the	the	DET
biomedich-730	39	6	heart	heart	NOUN
biomedich-730	39	7	,	,	PUNCT
biomedich-730	39	8	brain	brain	NOUN
biomedich-730	39	9	,	,	PUNCT
biomedich-730	39	10	adrenal	adrenal	ADJ
biomedich-730	39	11	glands	gland	NOUN
biomedich-730	39	12	,	,	PUNCT
biomedich-730	39	13	kidneys	kidney	NOUN
biomedich-730	39	14	,	,	PUNCT
biomedich-730	39	15	and	and	CCONJ
biomedich-730	39	16	liver	liver	NOUN
biomedich-730	39	17	(	(	PUNCT
biomedich-730	39	18	kumar	kumar	PROPN
biomedich-730	39	19	&	&	CCONJ
biomedich-730	39	20	pandey	pandey	PROPN
biomedich-730	39	21	,	,	PUNCT
biomedich-730	39	22	2013	2013	NUM
biomedich-730	39	23	)	)	PUNCT
biomedich-730	39	24	.	.	PUNCT
biomedich-730	40	1	at1r	at1r	PROPN
biomedich-730	40	2	comprises	comprise	VERB
biomedich-730	40	3	359	359	NUM
biomedich-730	40	4	amino	amino	ADJ
biomedich-730	40	5	acids	acid	NOUN
biomedich-730	40	6	and	and	CCONJ
biomedich-730	40	7	has	have	VERB
biomedich-730	40	8	a	a	DET
biomedich-730	40	9	molecular	molecular	ADJ
biomedich-730	40	10	weight	weight	NOUN
biomedich-730	40	11	of	of	ADP
biomedich-730	40	12	4	4	NUM
biomedich-730	40	13	kda	kda	NOUN
biomedich-730	40	14	.	.	PUNCT
biomedich-730	41	1	the	the	DET
biomedich-730	41	2	amino	amino	NOUN
biomedich-730	41	3	acid	acid	NOUN
biomedich-730	41	4	residues	residue	NOUN
biomedich-730	41	5	arg167	arg167	PROPN
biomedich-730	41	6	and	and	CCONJ
biomedich-730	41	7	tyr35	tyr35	PROPN
biomedich-730	41	8	are	be	AUX
biomedich-730	41	9	involved	involve	VERB
biomedich-730	41	10	in	in	ADP
biomedich-730	41	11	the	the	DET
biomedich-730	41	12	interaction	interaction	NOUN
biomedich-730	41	13	between	between	ADP
biomedich-730	41	14	arb	arb	NOUN
biomedich-730	41	15	drugs	drug	NOUN
biomedich-730	41	16	and	and	CCONJ
biomedich-730	41	17	at1r	at1r	PROPN
biomedich-730	41	18	(	(	PUNCT
biomedich-730	41	19	miura	miura	PROPN
biomedich-730	41	20	,	,	PUNCT
biomedich-730	41	21	2011	2011	NUM
biomedich-730	41	22	)	)	PUNCT
biomedich-730	41	23	.	.	PUNCT
biomedich-730	42	1	evaluating	evaluate	VERB
biomedich-730	42	2	the	the	DET
biomedich-730	42	3	efficacy	efficacy	NOUN
biomedich-730	42	4	of	of	ADP
biomedich-730	42	5	flavonoids	flavonoid	NOUN
biomedich-730	42	6	as	as	ADP
biomedich-730	42	7	substitutes	substitute	NOUN
biomedich-730	42	8	for	for	ADP
biomedich-730	42	9	ace	ace	ADJ
biomedich-730	42	10	inhibitors	inhibitor	NOUN
biomedich-730	42	11	(	(	PUNCT
biomedich-730	42	12	acei	acei	NOUN
biomedich-730	42	13	)	)	PUNCT
biomedich-730	42	14	and	and	CCONJ
biomedich-730	42	15	angiotensin	angiotensin	NOUN
biomedich-730	42	16	receptor	receptor	NOUN
biomedich-730	42	17	blockers	blocker	NOUN
biomedich-730	42	18	(	(	PUNCT
biomedich-730	42	19	arb	arb	NOUN
biomedich-730	42	20	)	)	PUNCT
biomedich-730	42	21	using	use	VERB
biomedich-730	42	22	in	in	ADP
biomedich-730	42	23	silico	silico	NOUN
biomedich-730	42	24	molecular	molecular	ADJ
biomedich-730	42	25	docking	docking	NOUN
biomedich-730	42	26	with	with	ADP
biomedich-730	42	27	the	the	DET
biomedich-730	42	28	angiotensin	angiotensin	NOUN
biomedich-730	42	29	ii	ii	PROPN
biomedich-730	42	30	type	type	NOUN
biomedich-730	42	31	1	1	NUM
biomedich-730	42	32	receptor	receptor	NOUN
biomedich-730	42	33	(	(	PUNCT
biomedich-730	42	34	at1r	at1r	NOUN
biomedich-730	42	35	)	)	PUNCT
biomedich-730	42	36	target	target	NOUN
biomedich-730	42	37	protein	protein	NOUN
biomedich-730	42	38	.	.	PUNCT
biomedich-730	43	1	this	this	DET
biomedich-730	43	2	study	study	NOUN
biomedich-730	43	3	attempts	attempt	VERB
biomedich-730	43	4	to	to	PART
biomedich-730	43	5	analyze	analyze	VERB
biomedich-730	43	6	the	the	DET
biomedich-730	43	7	interaction	interaction	NOUN
biomedich-730	43	8	and	and	CCONJ
biomedich-730	43	9	binding	bind	VERB
biomedich-730	43	10	affinity	affinity	NOUN
biomedich-730	43	11	of	of	ADP
biomedich-730	43	12	flavonoids	flavonoid	NOUN
biomedich-730	43	13	to	to	ADP
biomedich-730	43	14	at1r	at1r	PROPN
biomedich-730	43	15	in	in	ADP
biomedich-730	43	16	comparison	comparison	NOUN
biomedich-730	43	17	to	to	ADP
biomedich-730	43	18	conventional	conventional	ADJ
biomedich-730	43	19	ace	ace	NOUN
biomedich-730	43	20	inhibitors	inhibitor	NOUN
biomedich-730	43	21	and	and	CCONJ
biomedich-730	43	22	angiotensin	angiotensin	NOUN
biomedich-730	43	23	receptor	receptor	NOUN
biomedich-730	43	24	blockers	blocker	NOUN
biomedich-730	43	25	,	,	PUNCT
biomedich-730	43	26	as	as	ADP
biomedich-730	43	27	a	a	DET
biomedich-730	43	28	foundation	foundation	NOUN
biomedich-730	43	29	for	for	ADP
biomedich-730	43	30	the	the	DET
biomedich-730	43	31	development	development	NOUN
biomedich-730	43	32	of	of	ADP
biomedich-730	43	33	antihypertensive	antihypertensive	ADJ
biomedich-730	43	34	therapies	therapy	NOUN
biomedich-730	43	35	based	base	VERB
biomedich-730	43	36	on	on	ADP
biomedich-730	43	37	natural	natural	ADJ
biomedich-730	43	38	compounds	compound	NOUN
biomedich-730	43	39	.	.	PUNCT
biomedich-730	44	1	materials	material	NOUN
biomedich-730	44	2	and	and	CCONJ
biomedich-730	44	3	methods	method	NOUN
biomedich-730	44	4	study	study	NOUN
biomedich-730	44	5	area	area	NOUN
biomedich-730	44	6	for	for	ADP
biomedich-730	44	7	molecular	molecular	ADJ
biomedich-730	44	8	docking	docking	NOUN
biomedich-730	44	9	process	process	NOUN
biomedich-730	44	10	,	,	PUNCT
biomedich-730	44	11	this	this	DET
biomedich-730	44	12	study	study	NOUN
biomedich-730	44	13	used	use	VERB
biomedich-730	44	14	a	a	DET
biomedich-730	44	15	computer	computer	NOUN
biomedich-730	44	16	with	with	ADP
biomedich-730	44	17	specifications	specification	NOUN
biomedich-730	44	18	intel(r	intel(r	NOUN
biomedich-730	44	19	)	)	PUNCT
biomedich-730	44	20	celeron(r	celeron(r	NOUN
biomedich-730	44	21	)	)	PUNCT
biomedich-730	44	22	n4020	n4020	PRON
biomedich-730	44	23	cpu	cpu	VERB
biomedich-730	44	24	@	@	ADP
biomedich-730	44	25	1.10ghz	1.10ghz	NUM
biomedich-730	44	26	,	,	PUNCT
biomedich-730	44	27	1101	1101	NUM
biomedich-730	44	28	mhz	mhz	NOUN
biomedich-730	44	29	,	,	PUNCT
biomedich-730	44	30	2	2	NUM
biomedich-730	44	31	core(s	core(s	NOUN
biomedich-730	44	32	)	)	PUNCT
biomedich-730	44	33	,	,	PUNCT
biomedich-730	44	34	2	2	NUM
biomedich-730	44	35	logical	logical	ADJ
biomedich-730	44	36	processor(s	processor(s	NOUN
biomedich-730	44	37	)	)	PUNCT
biomedich-730	44	38	,	,	PUNCT
biomedich-730	44	39	4	4	NUM
biomedich-730	44	40	gb	gb	NOUN
biomedich-730	44	41	ram	ram	NOUN
biomedich-730	44	42	,	,	PUNCT
biomedich-730	44	43	and	and	CCONJ
biomedich-730	44	44	operating	operating	NOUN
biomedich-730	44	45	system	system	NOUN
biomedich-730	44	46	:	:	PUNCT
biomedich-730	44	47	microsoft	microsoft	PROPN
biomedich-730	44	48	windows	window	VERB
biomedich-730	44	49	11	11	NUM
biomedich-730	44	50	home	home	NOUN
biomedich-730	44	51	single	single	ADJ
biomedich-730	44	52	language	language	NOUN
biomedich-730	44	53	(	(	PUNCT
biomedich-730	44	54	10.0.22631	10.0.22631	PROPN
biomedich-730	44	55	build	build	VERB
biomedich-730	44	56	22631	22631	NUM
biomedich-730	44	57	)	)	PUNCT
biomedich-730	44	58	bios	bio	NOUN
biomedich-730	44	59	:	:	PUNCT
biomedich-730	44	60	dvcn17ww	dvcn17ww	VERB
biomedich-730	44	61	procedures	procedure	NOUN
biomedich-730	44	62	preparation	preparation	NOUN
biomedich-730	44	63	and	and	CCONJ
biomedich-730	44	64	ligands	ligand	NOUN
biomedich-730	44	65	the	the	DET
biomedich-730	44	66	test	test	NOUN
biomedich-730	44	67	compounds	compound	NOUN
biomedich-730	44	68	used	use	VERB
biomedich-730	44	69	are	be	AUX
biomedich-730	44	70	bioactive	bioactive	ADJ
biomedich-730	44	71	compounds	compound	NOUN
biomedich-730	44	72	sourced	source	VERB
biomedich-730	44	73	from	from	ADP
biomedich-730	44	74	the	the	DET
biomedich-730	44	75	majority	majority	NOUN
biomedich-730	44	76	of	of	ADP
biomedich-730	44	77	plants	plant	NOUN
biomedich-730	44	78	that	that	PRON
biomedich-730	44	79	grow	grow	VERB
biomedich-730	44	80	in	in	ADP
biomedich-730	44	81	indonesia	indonesia	PROPN
biomedich-730	44	82	,	,	PUNCT
biomedich-730	44	83	malaysia	malaysia	PROPN
biomedich-730	44	84	,	,	PUNCT
biomedich-730	44	85	thailand	thailand	PROPN
biomedich-730	44	86	and	and	CCONJ
biomedich-730	44	87	other	other	ADJ
biomedich-730	44	88	asian	asian	ADJ
biomedich-730	44	89	countries	country	NOUN
biomedich-730	44	90	,	,	PUNCT
biomedich-730	44	91	namely	namely	ADV
biomedich-730	44	92	flavonoids	flavonoid	NOUN
biomedich-730	44	93	(	(	PUNCT
biomedich-730	44	94	de	de	X
biomedich-730	44	95	vries	vries	PROPN
biomedich-730	44	96	,	,	PUNCT
biomedich-730	44	97	2020	2020	NUM
biomedich-730	44	98	)	)	PUNCT
biomedich-730	44	99	.	.	PUNCT
biomedich-730	45	1	numerous	numerous	ADJ
biomedich-730	45	2	angiotensin	angiotensin	NOUN
biomedich-730	45	3	receptor	receptor	NOUN
biomedich-730	45	4	blockers	blocker	NOUN
biomedich-730	45	5	(	(	PUNCT
biomedich-730	45	6	arb	arb	NOUN
biomedich-730	45	7	)	)	PUNCT
biomedich-730	45	8	medications	medication	NOUN
biomedich-730	45	9	were	be	AUX
biomedich-730	45	10	utilized	utilize	VERB
biomedich-730	45	11	to	to	PART
biomedich-730	45	12	evaluate	evaluate	VERB
biomedich-730	45	13	and	and	CCONJ
biomedich-730	45	14	compare	compare	VERB
biomedich-730	45	15	their	their	PRON
biomedich-730	45	16	binding	bind	VERB
biomedich-730	45	17	affinity	affinity	NOUN
biomedich-730	45	18	to	to	ADP
biomedich-730	45	19	flavonoids	flavonoid	NOUN
biomedich-730	45	20	(	(	PUNCT
biomedich-730	45	21	hermida	hermida	PROPN
biomedich-730	45	22	et	et	PROPN
biomedich-730	45	23	al	al	PROPN
biomedich-730	45	24	.	.	PROPN
biomedich-730	45	25	,	,	PUNCT
biomedich-730	45	26	2011	2011	NUM
biomedich-730	45	27	)	)	PUNCT
biomedich-730	45	28	.	.	PUNCT
biomedich-730	46	1	utilizing	utilize	VERB
biomedich-730	46	2	their	their	PRON
biomedich-730	46	3	canonical	canonical	ADJ
biomedich-730	46	4	smiles	smile	NOUN
biomedich-730	46	5	as	as	SCONJ
biomedich-730	46	6	the	the	DET
biomedich-730	46	7	input	input	NOUN
biomedich-730	46	8	and	and	CCONJ
biomedich-730	46	9	the	the	DET
biomedich-730	46	10	two	two	NUM
biomedich-730	46	11	-	-	PUNCT
biomedich-730	46	12	dimensional	dimensional	ADJ
biomedich-730	46	13	and	and	CCONJ
biomedich-730	46	14	three	three	NUM
biomedich-730	46	15	-	-	PUNCT
biomedich-730	46	16	dimensional	dimensional	ADJ
biomedich-730	46	17	structures	structure	NOUN
biomedich-730	46	18	of	of	ADP
biomedich-730	46	19	the	the	DET
biomedich-730	46	20	chosen	choose	VERB
biomedich-730	46	21	ligands	ligand	NOUN
biomedich-730	46	22	and	and	CCONJ
biomedich-730	46	23	protein	protein	NOUN
biomedich-730	46	24	were	be	AUX
biomedich-730	46	25	obtained	obtain	VERB
biomedich-730	46	26	from	from	ADP
biomedich-730	46	27	pubchem	pubchem	NOUN
biomedich-730	46	28	(	(	PUNCT
biomedich-730	46	29	https://pubchem.ncbi.nlm.nih.gov/	https://pubchem.ncbi.nlm.nih.gov/	PROPN
biomedich-730	46	30	)	)	PUNCT
biomedich-730	46	31	in	in	ADP
biomedich-730	46	32	sdf	sdf	PROPN
biomedich-730	46	33	format	format	NOUN
biomedich-730	46	34	(	(	PUNCT
biomedich-730	46	35	sri	sri	PROPN
biomedich-730	46	36	prakash	prakash	PROPN
biomedich-730	46	37	et	et	PROPN
biomedich-730	46	38	al	al	PROPN
biomedich-730	46	39	.	.	PROPN
biomedich-730	46	40	,	,	PUNCT
biomedich-730	46	41	2023	2023	NUM
biomedich-730	46	42	)	)	PUNCT
biomedich-730	46	43	.	.	PUNCT
biomedich-730	47	1	comprehending	comprehend	VERB
biomedich-730	47	2	the	the	DET
biomedich-730	47	3	molecular	molecular	ADJ
biomedich-730	47	4	mechanisms	mechanism	NOUN
biomedich-730	47	5	that	that	PRON
biomedich-730	47	6	regulate	regulate	VERB
biomedich-730	47	7	bioactivity	bioactivity	NOUN
biomedich-730	47	8	and	and	CCONJ
biomedich-730	47	9	forecasting	forecast	VERB
biomedich-730	47	10	potential	potential	ADJ
biomedich-730	47	11	side	side	NOUN
biomedich-730	47	12	effects	effect	NOUN
biomedich-730	47	13	or	or	CCONJ
biomedich-730	47	14	cross	cross	NOUN
biomedich-730	47	15	-	-	ADJ
biomedich-730	47	16	reactivity	reactivity	NOUN
biomedich-730	47	17	necessitates	necessitate	VERB
biomedich-730	47	18	the	the	DET
biomedich-730	47	19	identification	identification	NOUN
biomedich-730	47	20	of	of	ADP
biomedich-730	47	21	phytochemical	phytochemical	ADJ
biomedich-730	47	22	targets	target	NOUN
biomedich-730	47	23	.	.	PUNCT
biomedich-730	48	1	swiss	swiss	ADJ
biomedich-730	48	2	target	target	NOUN
biomedich-730	48	3	prediction(http://www.swisstargetprediction.ch/	prediction(http://www.swisstargetprediction.ch/	NOUN
biomedich-730	48	4	)	)	PUNCT
biomedich-730	48	5	analyzes	analyze	VERB
biomedich-730	48	6	ligand	ligand	NOUN
biomedich-730	48	7	configurations	configuration	NOUN
biomedich-730	48	8	against	against	ADP
biomedich-730	48	9	known	know	VERB
biomedich-730	48	10	drugs	drug	NOUN
biomedich-730	48	11	to	to	PART
biomedich-730	48	12	identify	identify	VERB
biomedich-730	48	13	protein	protein	NOUN
biomedich-730	48	14	targets	target	NOUN
biomedich-730	48	15	.	.	PUNCT
biomedich-730	49	1	the	the	DET
biomedich-730	49	2	assessed	assess	VERB
biomedich-730	49	3	phytochemicals	phytochemical	NOUN
biomedich-730	49	4	'	'	PART
biomedich-730	49	5	targets	target	NOUN
biomedich-730	49	6	related	relate	VERB
biomedich-730	49	7	to	to	ADP
biomedich-730	49	8	a	a	DET
biomedich-730	49	9	specific	specific	ADJ
biomedich-730	49	10	drug	drug	NOUN
biomedich-730	49	11	are	be	AUX
biomedich-730	49	12	identified	identify	VERB
biomedich-730	49	13	via	via	ADP
biomedich-730	49	14	swiss	swiss	ADJ
biomedich-730	49	15	target	target	NOUN
biomedich-730	49	16	prediction	prediction	NOUN
biomedich-730	49	17	(	(	PUNCT
biomedich-730	49	18	gfeller	gfeller	NOUN
biomedich-730	49	19	et	et	PROPN
biomedich-730	49	20	al	al	PROPN
biomedich-730	49	21	.	.	PROPN
biomedich-730	49	22	,	,	PUNCT
biomedich-730	49	23	2014	2014	NUM
biomedich-730	49	24	)	)	PUNCT
biomedich-730	49	25	.	.	PUNCT
biomedich-730	50	1	among	among	ADP
biomedich-730	50	2	various	various	ADJ
biomedich-730	50	3	candidate	candidate	NOUN
biomedich-730	50	4	proteins	protein	NOUN
biomedich-730	50	5	that	that	PRON
biomedich-730	50	6	interact	interact	VERB
biomedich-730	50	7	with	with	ADP
biomedich-730	50	8	flavonoids	flavonoid	NOUN
biomedich-730	50	9	,	,	PUNCT
biomedich-730	50	10	we	we	PRON
biomedich-730	50	11	selected	select	VERB
biomedich-730	50	12	the	the	DET
biomedich-730	50	13	type-1	type-1	PROPN
biomedich-730	50	14	angiotensin	angiotensin	NOUN
biomedich-730	50	15	ii	ii	PROPN
biomedich-730	50	16	receptor	receptor	NOUN
biomedich-730	50	17	(	(	PUNCT
biomedich-730	50	18	at1r	at1r	NOUN
biomedich-730	50	19	)	)	PUNCT
biomedich-730	50	20	as	as	SCONJ
biomedich-730	50	21	the	the	DET
biomedich-730	50	22	target	target	NOUN
biomedich-730	50	23	to	to	PART
biomedich-730	50	24	evaluate	evaluate	VERB
biomedich-730	50	25	its	its	PRON
biomedich-730	50	26	binding	bind	VERB
biomedich-730	50	27	affinity	affinity	NOUN
biomedich-730	50	28	and	and	CCONJ
biomedich-730	50	29	to	to	PART
biomedich-730	50	30	compare	compare	VERB
biomedich-730	50	31	it	it	PRON
biomedich-730	50	32	with	with	ADP
biomedich-730	50	33	the	the	DET
biomedich-730	50	34	binding	bind	VERB
biomedich-730	50	35	affinities	affinity	NOUN
biomedich-730	50	36	of	of	ADP
biomedich-730	50	37	ace	ace	NOUN
biomedich-730	50	38	and	and	CCONJ
biomedich-730	50	39	arb	arb	PROPN
biomedich-730	50	40	.	.	PROPN
biomedich-730	50	41	target	target	NOUN
biomedich-730	50	42	selection	selection	NOUN
biomedich-730	50	43	and	and	CCONJ
biomedich-730	50	44	validation	validation	NOUN
biomedich-730	50	45	at1r	at1r	PROPN
biomedich-730	50	46	was	be	AUX
biomedich-730	50	47	selected	select	VERB
biomedich-730	50	48	as	as	ADP
biomedich-730	50	49	the	the	DET
biomedich-730	50	50	protein	protein	NOUN
biomedich-730	50	51	of	of	ADP
biomedich-730	50	52	interest	interest	NOUN
biomedich-730	50	53	for	for	ADP
biomedich-730	50	54	the	the	DET
biomedich-730	50	55	study	study	NOUN
biomedich-730	50	56	.	.	PUNCT
biomedich-730	51	1	the	the	PRON
biomedich-730	51	2	swiss	swiss	ADJ
biomedich-730	51	3	-	-	PUNCT
biomedich-730	51	4	model	model	NOUN
biomedich-730	51	5	(	(	PUNCT
biomedich-730	51	6	https://swissmodel.expasy.org/	https://swissmodel.expasy.org/	NOUN
biomedich-730	51	7	)	)	PUNCT
biomedich-730	51	8	was	be	AUX
biomedich-730	51	9	utilized	utilize	VERB
biomedich-730	51	10	to	to	PART
biomedich-730	51	11	predict	predict	VERB
biomedich-730	51	12	the	the	DET
biomedich-730	51	13	three	three	NUM
biomedich-730	51	14	-	-	PUNCT
biomedich-730	51	15	dimensional	dimensional	ADJ
biomedich-730	51	16	structure	structure	NOUN
biomedich-730	51	17	of	of	ADP
biomedich-730	51	18	the	the	DET
biomedich-730	51	19	at1r	at1r	PROPN
biomedich-730	51	20	protein	protein	NOUN
biomedich-730	51	21	(	(	PUNCT
biomedich-730	51	22	ali	ali	PROPN
biomedich-730	51	23	et	et	PROPN
biomedich-730	51	24	al	al	PROPN
biomedich-730	51	25	.	.	PROPN
biomedich-730	51	26	,	,	PUNCT
biomedich-730	51	27	2024	2024	NUM
biomedich-730	51	28	)	)	PUNCT
biomedich-730	51	29	.	.	PUNCT
biomedich-730	52	1	subsequently	subsequently	ADV
biomedich-730	52	2	conducted	conduct	VERB
biomedich-730	52	3	protein	protein	NOUN
biomedich-730	52	4	validation	validation	NOUN
biomedich-730	52	5	utilizing	utilize	VERB
biomedich-730	52	6	procheck	procheck	NOUN
biomedich-730	52	7	and	and	CCONJ
biomedich-730	52	8	errat	errat	NOUN
biomedich-730	52	9	using	use	VERB
biomedich-730	52	10	saves	save	NOUN
biomedich-730	52	11	(	(	PUNCT
biomedich-730	52	12	https://saves.mbi.ucla.edu/	https://saves.mbi.ucla.edu/	NOUN
biomedich-730	52	13	)	)	PUNCT
biomedich-730	52	14	(	(	PUNCT
biomedich-730	52	15	deka	deka	NOUN
biomedich-730	52	16	et	et	PROPN
biomedich-730	52	17	al	al	PROPN
biomedich-730	52	18	.	.	PROPN
biomedich-730	52	19	,	,	PUNCT
biomedich-730	52	20	2015	2015	NUM
biomedich-730	52	21	;	;	PUNCT
biomedich-730	52	22	mariana	mariana	PROPN
biomedich-730	52	23	et	et	PROPN
biomedich-730	52	24	al	al	PROPN
biomedich-730	52	25	.	.	PROPN
biomedich-730	52	26	,	,	PUNCT
biomedich-730	52	27	2023	2023	NUM
biomedich-730	52	28	)	)	PUNCT
biomedich-730	52	29	.	.	PUNCT
biomedich-730	53	1	pymol	pymol	PROPN
biomedich-730	53	2	(	(	PUNCT
biomedich-730	53	3	https://pymol.org/2/	https://pymol.org/2/	PROPN
biomedich-730	53	4	)	)	PUNCT
biomedich-730	53	5	is	be	AUX
biomedich-730	53	6	used	use	VERB
biomedich-730	53	7	for	for	ADP
biomedich-730	53	8	three	three	NUM
biomedich-730	53	9	-	-	PUNCT
biomedich-730	53	10	dimensional	dimensional	ADJ
biomedich-730	53	11	visualization	visualization	NOUN
biomedich-730	53	12	of	of	ADP
biomedich-730	53	13	proteins	protein	NOUN
biomedich-730	53	14	and	and	CCONJ
biomedich-730	53	15	the	the	DET
biomedich-730	53	16	receptor	receptor	NOUN
biomedich-730	53	17	was	be	AUX
biomedich-730	53	18	modified	modify	VERB
biomedich-730	53	19	by	by	ADP
biomedich-730	53	20	the	the	DET
biomedich-730	53	21	removal	removal	NOUN
biomedich-730	53	22	of	of	ADP
biomedich-730	53	23	water	water	NOUN
biomedich-730	53	24	(	(	PUNCT
biomedich-730	53	25	putra	putra	PROPN
biomedich-730	53	26	et	et	PROPN
biomedich-730	53	27	al	al	PROPN
biomedich-730	53	28	.	.	PROPN
biomedich-730	53	29	,	,	PUNCT
biomedich-730	53	30	2024	2024	NUM
biomedich-730	53	31	)	)	PUNCT
biomedich-730	53	32	.	.	PUNCT
biomedich-730	54	1	docking	dock	VERB
biomedich-730	54	2	molecules	molecule	NOUN
biomedich-730	54	3	docking	docking	NOUN
biomedich-730	54	4	study	study	NOUN
biomedich-730	54	5	was	be	AUX
biomedich-730	54	6	conducted	conduct	VERB
biomedich-730	54	7	using	use	VERB
biomedich-730	54	8	autodock	autodock	ADJ
biomedich-730	54	9	vina	vina	NOUN
biomedich-730	54	10	in	in	ADP
biomedich-730	54	11	pyrx	pyrx	NOUN
biomedich-730	54	12	software	software	NOUN
biomedich-730	54	13	(	(	PUNCT
biomedich-730	54	14	https://pyrx.sourceforge.io/	https://pyrx.sourceforge.io/	PROPN
biomedich-730	54	15	)	)	PUNCT
biomedich-730	54	16	,	,	PUNCT
biomedich-730	54	17	throughout	throughout	ADP
biomedich-730	54	18	the	the	DET
biomedich-730	54	19	docking	docking	NOUN
biomedich-730	54	20	phase	phase	NOUN
biomedich-730	54	21	,	,	PUNCT
biomedich-730	54	22	the	the	DET
biomedich-730	54	23	ligands	ligand	NOUN
biomedich-730	54	24	were	be	AUX
biomedich-730	54	25	regarded	regard	VERB
biomedich-730	54	26	as	as	ADP
biomedich-730	54	27	flexible	flexible	ADJ
biomedich-730	54	28	(	(	PUNCT
biomedich-730	54	29	prasanth	prasanth	NOUN
biomedich-730	54	30	et	et	PROPN
biomedich-730	54	31	al	al	PROPN
biomedich-730	54	32	.	.	PROPN
biomedich-730	54	33	,	,	PUNCT
biomedich-730	54	34	2021	2021	NUM
biomedich-730	54	35	)	)	PUNCT
biomedich-730	54	36	.	.	PUNCT
biomedich-730	55	1	the	the	DET
biomedich-730	55	2	molecular	molecular	ADJ
biomedich-730	55	3	docking	docking	NOUN
biomedich-730	55	4	results	result	NOUN
biomedich-730	55	5	of	of	ADP
biomedich-730	55	6	the	the	DET
biomedich-730	55	7	protein	protein	NOUN
biomedich-730	55	8	-	-	PUNCT
biomedich-730	55	9	ligand	ligand	NOUN
biomedich-730	55	10	interaction	interaction	NOUN
biomedich-730	55	11	were	be	AUX
biomedich-730	55	12	analyzed	analyze	VERB
biomedich-730	55	13	using	use	VERB
biomedich-730	55	14	the	the	DET
biomedich-730	55	15	pymol	pymol	NOUN
biomedich-730	55	16	software	software	NOUN
biomedich-730	55	17	(	(	PUNCT
biomedich-730	55	18	uma	uma	PROPN
biomedich-730	55	19	maheswari	maheswari	PROPN
biomedich-730	55	20	&	&	CCONJ
biomedich-730	55	21	sankar	sankar	PROPN
biomedich-730	55	22	,	,	PUNCT
biomedich-730	55	23	2024	2024	NUM
biomedich-730	55	24	)	)	PUNCT
biomedich-730	55	25	.	.	PUNCT
biomedich-730	56	1	data	datum	NOUN
biomedich-730	56	2	analysis	analysis	NOUN
biomedich-730	56	3	drug	drug	NOUN
biomedich-730	56	4	development	development	NOUN
biomedich-730	56	5	entails	entail	VERB
biomedich-730	56	6	the	the	DET
biomedich-730	56	7	evaluation	evaluation	NOUN
biomedich-730	56	8	of	of	ADP
biomedich-730	56	9	absorption	absorption	NOUN
biomedich-730	56	10	,	,	PUNCT
biomedich-730	56	11	distribution	distribution	NOUN
biomedich-730	56	12	,	,	PUNCT
biomedich-730	56	13	metabolism	metabolism	NOUN
biomedich-730	56	14	,	,	PUNCT
biomedich-730	56	15	and	and	CCONJ
biomedich-730	56	16	excretion	excretion	NOUN
biomedich-730	56	17	(	(	PUNCT
biomedich-730	56	18	adme	adme	NOUN
biomedich-730	56	19	)	)	PUNCT
biomedich-730	56	20	at	at	ADP
biomedich-730	56	21	progressively	progressively	ADV
biomedich-730	56	22	earlier	early	ADJ
biomedich-730	56	23	stages	stage	NOUN
biomedich-730	56	24	of	of	ADP
biomedich-730	56	25	the	the	DET
biomedich-730	56	26	discovery	discovery	NOUN
biomedich-730	56	27	process	process	NOUN
biomedich-730	56	28	,	,	PUNCT
biomedich-730	56	29	when	when	SCONJ
biomedich-730	56	30	numerous	numerous	ADJ
biomedich-730	56	31	compounds	compound	NOUN
biomedich-730	56	32	are	be	AUX
biomedich-730	56	33	under	under	ADP
biomedich-730	56	34	consideration	consideration	NOUN
biomedich-730	56	35	but	but	CCONJ
biomedich-730	56	36	access	access	NOUN
biomedich-730	56	37	to	to	ADP
biomedich-730	56	38	physical	physical	ADJ
biomedich-730	56	39	samples	sample	NOUN
biomedich-730	56	40	is	be	AUX
biomedich-730	56	41	restricted	restrict	VERB
biomedich-730	56	42	.	.	PUNCT
biomedich-730	57	1	a	a	DET
biomedich-730	57	2	potent	potent	ADJ
biomedich-730	57	3	molecule	molecule	NOUN
biomedich-730	57	4	must	must	AUX
biomedich-730	57	5	arrive	arrive	VERB
biomedich-730	57	6	at	at	ADP
biomedich-730	57	7	its	its	PRON
biomedich-730	57	8	target	target	NOUN
biomedich-730	57	9	.	.	PUNCT
biomedich-730	58	1	achieve	achieve	VERB
biomedich-730	58	2	adequate	adequate	ADJ
biomedich-730	58	3	concentration	concentration	NOUN
biomedich-730	58	4	within	within	ADP
biomedich-730	58	5	the	the	DET
biomedich-730	58	6	body	body	NOUN
biomedich-730	58	7	and	and	CCONJ
biomedich-730	58	8	maintain	maintain	VERB
biomedich-730	58	9	a	a	DET
biomedich-730	58	10	bioactive	bioactive	ADJ
biomedich-730	58	11	state	state	NOUN
biomedich-730	58	12	for	for	ADP
biomedich-730	58	13	an	an	DET
biomedich-730	58	14	extended	extended	ADJ
biomedich-730	58	15	duration	duration	NOUN
biomedich-730	58	16	for	for	SCONJ
biomedich-730	58	17	the	the	DET
biomedich-730	58	18	expected	expect	VERB
biomedich-730	58	19	biological	biological	ADJ
biomedich-730	58	20	event	event	NOUN
biomedich-730	58	21	to	to	PART
biomedich-730	58	22	transpire	transpire	VERB
biomedich-730	58	23	to	to	PART
biomedich-730	58	24	be	be	AUX
biomedich-730	58	25	efficacious	efficacious	ADJ
biomedich-730	58	26	as	as	ADP
biomedich-730	58	27	a	a	DET
biomedich-730	58	28	pharmaceutical	pharmaceutical	ADJ
biomedich-730	58	29	agent	agent	NOUN
biomedich-730	58	30	.	.	PUNCT
biomedich-730	59	1	for	for	ADP
biomedich-730	59	2	this	this	DET
biomedich-730	59	3	purpose	purpose	NOUN
biomedich-730	59	4	,	,	PUNCT
biomedich-730	59	5	adme	adme	VERB
biomedich-730	59	6	analysis	analysis	NOUN
biomedich-730	59	7	for	for	ADP
biomedich-730	59	8	flavonoids	flavonoid	NOUN
biomedich-730	59	9	is	be	AUX
biomedich-730	59	10	delineated	delineate	VERB
biomedich-730	59	11	by	by	ADP
biomedich-730	59	12	the	the	DET
biomedich-730	59	13	swissadme	swissadme	PROPN
biomedich-730	59	14	online	online	PROPN
biomedich-730	59	15	platform	platform	NOUN
biomedich-730	59	16	(	(	PUNCT
biomedich-730	59	17	http://www.swissadme.ch	http://www.swissadme.ch	NOUN
biomedich-730	59	18	)	)	PUNCT
biomedich-730	59	19	(	(	PUNCT
biomedich-730	59	20	daina	daina	PROPN
biomedich-730	59	21	et	et	PROPN
biomedich-730	59	22	al	al	PROPN
biomedich-730	59	23	.	.	PROPN
biomedich-730	59	24	,	,	PUNCT
biomedich-730	59	25	2017	2017	NUM
biomedich-730	59	26	;	;	PUNCT
biomedich-730	59	27	ismail	ismail	PROPN
biomedich-730	59	28	et	et	PROPN
biomedich-730	59	29	al	al	PROPN
biomedich-730	59	30	.	.	PROPN
biomedich-730	59	31	,	,	PUNCT
biomedich-730	59	32	2023	2023	NUM
biomedich-730	59	33	)	)	PUNCT
biomedich-730	59	34	.	.	PUNCT
biomedich-730	60	1	next	next	ADV
biomedich-730	60	2	to	to	ADP
biomedich-730	60	3	docking	docking	NOUN
biomedich-730	60	4	,	,	PUNCT
biomedich-730	60	5	the	the	DET
biomedich-730	60	6	next	next	ADJ
biomedich-730	60	7	process	process	NOUN
biomedich-730	60	8	involves	involve	VERB
biomedich-730	60	9	predicting	predict	VERB
biomedich-730	60	10	the	the	DET
biomedich-730	60	11	toxicity	toxicity	NOUN
biomedich-730	60	12	status	status	NOUN
biomedich-730	60	13	of	of	ADP
biomedich-730	60	14	the	the	DET
biomedich-730	60	15	natural	natural	ADJ
biomedich-730	60	16	ligands	ligand	NOUN
biomedich-730	60	17	(	(	PUNCT
biomedich-730	60	18	flavonoids	flavonoid	NOUN
biomedich-730	60	19	)	)	PUNCT
biomedich-730	60	20	utilizing	utilize	VERB
biomedich-730	60	21	the	the	DET
biomedich-730	60	22	'	'	PUNCT
biomedich-730	60	23	protox	protox	NOUN
biomedich-730	60	24	-	-	PUNCT
biomedich-730	60	25	iii	iii	NOUN
biomedich-730	60	26	'	'	PART
biomedich-730	60	27	web	web	NOUN
biomedich-730	60	28	server	server	NOUN
biomedich-730	60	29	(	(	PUNCT
biomedich-730	60	30	https://tox.charite.de/protox3/	https://tox.charite.de/protox3/	PROPN
biomedich-730	60	31	)	)	PUNCT
biomedich-730	60	32	(	(	PUNCT
biomedich-730	60	33	tithi	tithi	ADV
biomedich-730	60	34	et	et	PROPN
biomedich-730	60	35	al	al	PROPN
biomedich-730	60	36	.	.	PROPN
biomedich-730	60	37	,	,	PUNCT
biomedich-730	60	38	2023	2023	NUM
biomedich-730	60	39	)	)	PUNCT
biomedich-730	60	40	.	.	PUNCT
biomedich-730	61	1	results	result	NOUN
biomedich-730	61	2	and	and	CCONJ
biomedich-730	61	3	discussion	discussion	NOUN
biomedich-730	61	4	ligands	ligand	NOUN
biomedich-730	61	5	and	and	CCONJ
biomedich-730	61	6	protein	protein	NOUN
biomedich-730	61	7	identification	identification	NOUN
biomedich-730	61	8	the	the	DET
biomedich-730	61	9	docking	docking	NOUN
biomedich-730	61	10	process	process	NOUN
biomedich-730	61	11	commences	commence	VERB
biomedich-730	61	12	with	with	ADP
biomedich-730	61	13	the	the	DET
biomedich-730	61	14	compilation	compilation	NOUN
biomedich-730	61	15	of	of	ADP
biomedich-730	61	16	a	a	DET
biomedich-730	61	17	database	database	NOUN
biomedich-730	61	18	of	of	ADP
biomedich-730	61	19	herbal	herbal	ADJ
biomedich-730	61	20	compounds	compound	NOUN
biomedich-730	61	21	from	from	ADP
biomedich-730	61	22	ocimum	ocimum	PROPN
biomedich-730	61	23	basilicum	basilicum	PROPN
biomedich-730	61	24	,	,	PUNCT
biomedich-730	61	25	thalib	thalib	PROPN
biomedich-730	61	26	&	&	CCONJ
biomedich-730	61	27	damayanti	damayanti	PROPN
biomedich-730	61	28	–	–	PUNCT
biomedich-730	61	29	in	in	ADP
biomedich-730	61	30	silico	silico	NOUN
biomedich-730	61	31	analysis	analysis	NOUN
biomedich-730	61	32	of	of	ADP
biomedich-730	61	33	ocimum	ocimum	ADJ
biomedich-730	61	34	basilicum	basilicum	NOUN
biomedich-730	61	35	flavonoids	flavonoid	NOUN
biomedich-730	61	36	as	as	ADP
biomedich-730	61	37	…	…	PUNCT
biomedich-730	61	38	277	277	NUM
biomedich-730	61	39	identifying	identify	VERB
biomedich-730	61	40	one	one	NUM
biomedich-730	61	41	active	active	ADJ
biomedich-730	61	42	compound	compound	NOUN
biomedich-730	61	43	from	from	ADP
biomedich-730	61	44	the	the	DET
biomedich-730	61	45	ocimum	ocimum	PROPN
biomedich-730	61	46	basilicum	basilicum	PROPN
biomedich-730	61	47	family	family	NOUN
biomedich-730	61	48	that	that	PRON
biomedich-730	61	49	exhibits	exhibit	VERB
biomedich-730	61	50	anti	anti	ADJ
biomedich-730	61	51	-	-	ADJ
biomedich-730	61	52	hypertensive	hypertensive	ADJ
biomedich-730	61	53	properties	property	NOUN
biomedich-730	61	54	associated	associate	VERB
biomedich-730	61	55	with	with	ADP
biomedich-730	61	56	the	the	DET
biomedich-730	61	57	type-1	type-1	PROPN
biomedich-730	61	58	angiotensin	angiotensin	NOUN
biomedich-730	61	59	ii	ii	PROPN
biomedich-730	61	60	receptor	receptor	NOUN
biomedich-730	61	61	,	,	PUNCT
biomedich-730	61	62	specifically	specifically	ADV
biomedich-730	61	63	flavonoids	flavonoid	NOUN
biomedich-730	61	64	.	.	PUNCT
biomedich-730	62	1	additionally	additionally	ADV
biomedich-730	62	2	,	,	PUNCT
biomedich-730	62	3	the	the	DET
biomedich-730	62	4	ligand	ligand	ADJ
biomedich-730	62	5	structure	structure	NOUN
biomedich-730	62	6	is	be	AUX
biomedich-730	62	7	generated	generate	VERB
biomedich-730	62	8	utilizing	utilize	VERB
biomedich-730	62	9	pubchem	pubchem	NOUN
biomedich-730	62	10	in	in	ADP
biomedich-730	62	11	sdf	sdf	PROPN
biomedich-730	62	12	format	format	NOUN
biomedich-730	62	13	.	.	PUNCT
biomedich-730	63	1	the	the	DET
biomedich-730	63	2	macromolecules	macromolecule	NOUN
biomedich-730	63	3	utilized	utilize	VERB
biomedich-730	63	4	in	in	ADP
biomedich-730	63	5	this	this	DET
biomedich-730	63	6	study	study	NOUN
biomedich-730	63	7	are	be	AUX
biomedich-730	63	8	type-1	type-1	NUM
biomedich-730	63	9	angiotensin	angiotensin	NOUN
biomedich-730	63	10	ii	ii	PROPN
biomedich-730	63	11	receptor	receptor	NOUN
biomedich-730	63	12	.	.	PUNCT
biomedich-730	64	1	this	this	DET
biomedich-730	64	2	study	study	NOUN
biomedich-730	64	3	pertains	pertain	VERB
biomedich-730	64	4	to	to	ADP
biomedich-730	64	5	the	the	DET
biomedich-730	64	6	type-1	type-1	PROPN
biomedich-730	64	7	angiotensin	angiotensin	NOUN
biomedich-730	64	8	ii	ii	PROPN
biomedich-730	64	9	receptor	receptor	NOUN
biomedich-730	64	10	downloaded	download	VERB
biomedich-730	64	11	from	from	ADP
biomedich-730	64	12	the	the	DET
biomedich-730	64	13	protein	protein	NOUN
biomedich-730	64	14	data	data	PROPN
biomedich-730	64	15	bank	bank	PROPN
biomedich-730	64	16	(	(	PUNCT
biomedich-730	64	17	pdb	pdb	PROPN
biomedich-730	64	18	)	)	PUNCT
biomedich-730	64	19	.	.	PUNCT
biomedich-730	65	1	receptors	receptor	NOUN
biomedich-730	65	2	generally	generally	ADV
biomedich-730	65	3	comprise	comprise	VERB
biomedich-730	65	4	water	water	NOUN
biomedich-730	65	5	molecules	molecule	NOUN
biomedich-730	65	6	and	and	CCONJ
biomedich-730	65	7	residues	residue	NOUN
biomedich-730	65	8	.	.	PUNCT
biomedich-730	66	1	consequently	consequently	ADV
biomedich-730	66	2	,	,	PUNCT
biomedich-730	66	3	water	water	NOUN
biomedich-730	66	4	molecules	molecule	NOUN
biomedich-730	66	5	and	and	CCONJ
biomedich-730	66	6	residues	residue	NOUN
biomedich-730	66	7	must	must	AUX
biomedich-730	66	8	be	be	AUX
biomedich-730	66	9	eliminated	eliminate	VERB
biomedich-730	66	10	,	,	PUNCT
biomedich-730	66	11	require	require	VERB
biomedich-730	66	12	preparation	preparation	NOUN
biomedich-730	66	13	with	with	ADP
biomedich-730	66	14	pymol	pymol	PROPN
biomedich-730	66	15	software	software	NOUN
biomedich-730	66	16	to	to	PART
biomedich-730	66	17	avoid	avoid	VERB
biomedich-730	66	18	disruption	disruption	NOUN
biomedich-730	66	19	during	during	ADP
biomedich-730	66	20	the	the	DET
biomedich-730	66	21	docking	docking	NOUN
biomedich-730	66	22	procedure	procedure	NOUN
biomedich-730	66	23	.	.	PUNCT
biomedich-730	67	1	this	this	DET
biomedich-730	67	2	study	study	NOUN
biomedich-730	67	3	employs	employ	VERB
biomedich-730	67	4	comparative	comparative	ADJ
biomedich-730	67	5	analysis	analysis	NOUN
biomedich-730	67	6	of	of	ADP
biomedich-730	67	7	arb	arb	NOUN
biomedich-730	67	8	class	class	NOUN
biomedich-730	67	9	drugs	drug	NOUN
biomedich-730	67	10	,	,	PUNCT
biomedich-730	67	11	specifically	specifically	ADV
biomedich-730	67	12	eprosartan	eprosartan	ADJ
biomedich-730	67	13	,	,	PUNCT
biomedich-730	67	14	azilsartan	azilsartan	ADJ
biomedich-730	67	15	,	,	PUNCT
biomedich-730	67	16	irbesartan	irbesartan	PROPN
biomedich-730	67	17	,	,	PUNCT
biomedich-730	67	18	telmisartan	telmisartan	PROPN
biomedich-730	67	19	,	,	PUNCT
biomedich-730	67	20	valsartan	valsartan	PROPN
biomedich-730	67	21	,	,	PUNCT
biomedich-730	67	22	losartan	losartan	PROPN
biomedich-730	67	23	,	,	PUNCT
biomedich-730	67	24	olmesartan	olmesartan	PROPN
biomedich-730	67	25	,	,	PUNCT
biomedich-730	67	26	and	and	CCONJ
biomedich-730	67	27	candesartan	candesartan	VERB
biomedich-730	67	28	as	as	ADP
biomedich-730	67	29	ligands	ligand	NOUN
biomedich-730	67	30	,	,	PUNCT
biomedich-730	67	31	which	which	PRON
biomedich-730	67	32	will	will	AUX
biomedich-730	67	33	be	be	AUX
biomedich-730	67	34	evaluated	evaluate	VERB
biomedich-730	67	35	against	against	ADP
biomedich-730	67	36	flavonoids	flavonoid	NOUN
biomedich-730	67	37	to	to	PART
biomedich-730	67	38	assess	assess	VERB
biomedich-730	67	39	their	their	PRON
biomedich-730	67	40	binding	bind	VERB
biomedich-730	67	41	affinity	affinity	NOUN
biomedich-730	67	42	to	to	ADP
biomedich-730	67	43	the	the	DET
biomedich-730	67	44	type-1	type-1	PROPN
biomedich-730	67	45	angiotensin	angiotensin	NOUN
biomedich-730	67	46	ii	ii	PROPN
biomedich-730	67	47	receptor	receptor	NOUN
biomedich-730	67	48	(	(	PUNCT
biomedich-730	67	49	figure	figure	NOUN
biomedich-730	67	50	1	1	NUM
biomedich-730	67	51	.	.	PUNCT
biomedich-730	67	52	)	)	PUNCT
biomedich-730	67	53	.	.	PUNCT
biomedich-730	68	1	figure	figure	NOUN
biomedich-730	68	2	1	1	NUM
biomedich-730	68	3	.	.	PUNCT
biomedich-730	68	4	visualization	visualization	NOUN
biomedich-730	68	5	of	of	ADP
biomedich-730	68	6	ligands	ligand	NOUN
biomedich-730	68	7	.	.	PUNCT
biomedich-730	69	1	(	(	PUNCT
biomedich-730	69	2	a	a	X
biomedich-730	69	3	)	)	PUNCT
biomedich-730	69	4	eprosartan	eprosartan	PROPN
biomedich-730	69	5	;	;	PUNCT
biomedich-730	69	6	(	(	PUNCT
biomedich-730	69	7	b	b	X
biomedich-730	69	8	)	)	PUNCT
biomedich-730	69	9	candesartan	candesartan	NOUN
biomedich-730	69	10	;	;	PUNCT
biomedich-730	69	11	(	(	PUNCT
biomedich-730	69	12	c	c	X
biomedich-730	69	13	)	)	PUNCT
biomedich-730	69	14	azilsartan	azilsartan	NOUN
biomedich-730	69	15	;	;	PUNCT
biomedich-730	69	16	(	(	PUNCT
biomedich-730	69	17	d	d	X
biomedich-730	69	18	)	)	PUNCT
biomedich-730	69	19	losartan	losartan	ADJ
biomedich-730	69	20	;	;	PUNCT
biomedich-730	69	21	(	(	PUNCT
biomedich-730	69	22	e	e	X
biomedich-730	69	23	)	)	PUNCT
biomedich-730	69	24	olmesartan	olmesartan	PROPN
biomedich-730	69	25	;	;	PUNCT
biomedich-730	69	26	(	(	PUNCT
biomedich-730	69	27	f	f	X
biomedich-730	69	28	)	)	PUNCT
biomedich-730	69	29	telmisartan	telmisartan	NOUN
biomedich-730	69	30	;	;	PUNCT
biomedich-730	69	31	(	(	PUNCT
biomedich-730	69	32	g	g	NOUN
biomedich-730	69	33	)	)	PUNCT
biomedich-730	69	34	valsartan	valsartan	PROPN
biomedich-730	69	35	;	;	PUNCT
biomedich-730	69	36	(	(	PUNCT
biomedich-730	69	37	h	h	NOUN
biomedich-730	69	38	)	)	PUNCT
biomedich-730	69	39	irbesartan	irbesartan	PROPN
biomedich-730	69	40	;	;	PUNCT
biomedich-730	69	41	(	(	PUNCT
biomedich-730	69	42	i	i	NOUN
biomedich-730	69	43	)	)	PUNCT
biomedich-730	69	44	natural	natural	ADJ
biomedich-730	69	45	ligand	ligand	ADJ
biomedich-730	69	46	flavonoids	flavonoid	NOUN
biomedich-730	69	47	.	.	PUNCT
biomedich-730	70	1	structure	structure	NOUN
biomedich-730	70	2	validation	validation	NOUN
biomedich-730	70	3	of	of	ADP
biomedich-730	70	4	modeled	model	VERB
biomedich-730	70	5	proteins	protein	NOUN
biomedich-730	70	6	validation	validation	NOUN
biomedich-730	70	7	is	be	AUX
biomedich-730	70	8	employed	employ	VERB
biomedich-730	70	9	to	to	PART
biomedich-730	70	10	verify	verify	VERB
biomedich-730	70	11	the	the	DET
biomedich-730	70	12	reliability	reliability	NOUN
biomedich-730	70	13	of	of	ADP
biomedich-730	70	14	the	the	DET
biomedich-730	70	15	protein	protein	NOUN
biomedich-730	70	16	structure	structure	NOUN
biomedich-730	70	17	for	for	ADP
biomedich-730	70	18	docking	docking	NOUN
biomedich-730	70	19	.	.	PUNCT
biomedich-730	71	1	the	the	DET
biomedich-730	71	2	protein	protein	NOUN
biomedich-730	71	3	structure	structure	NOUN
biomedich-730	71	4	validation	validation	NOUN
biomedich-730	71	5	was	be	AUX
biomedich-730	71	6	conducted	conduct	VERB
biomedich-730	71	7	utilizing	utilize	VERB
biomedich-730	71	8	the	the	DET
biomedich-730	71	9	procheck	procheck	NOUN
biomedich-730	71	10	ramachandran	ramachandran	PROPN
biomedich-730	71	11	plot	plot	PROPN
biomedich-730	71	12	and	and	CCONJ
biomedich-730	71	13	errat	errat	NOUN
biomedich-730	71	14	(	(	PUNCT
biomedich-730	71	15	hamid	hamid	PROPN
biomedich-730	71	16	et	et	PROPN
biomedich-730	71	17	al	al	PROPN
biomedich-730	71	18	.	.	PROPN
biomedich-730	71	19	,	,	PUNCT
biomedich-730	71	20	2021	2021	NUM
biomedich-730	71	21	)	)	PUNCT
biomedich-730	71	22	.	.	PUNCT
biomedich-730	72	1	errat	errat	PROPN
biomedich-730	72	2	errat	errat	NOUN
biomedich-730	72	3	assesses	assess	VERB
biomedich-730	72	4	the	the	DET
biomedich-730	72	5	model	model	NOUN
biomedich-730	72	6	using	use	VERB
biomedich-730	72	7	statistics	statistic	NOUN
biomedich-730	72	8	to	to	PART
biomedich-730	72	9	evaluate	evaluate	VERB
biomedich-730	72	10	unbound	unbound	NOUN
biomedich-730	72	11	interaction	interaction	NOUN
biomedich-730	72	12	relationships	relationship	NOUN
biomedich-730	72	13	among	among	ADP
biomedich-730	72	14	various	various	ADJ
biomedich-730	72	15	atom	atom	NOUN
biomedich-730	72	16	types	type	NOUN
biomedich-730	72	17	,	,	PUNCT
biomedich-730	72	18	where	where	SCONJ
biomedich-730	72	19	elevated	elevated	ADJ
biomedich-730	72	20	scores	score	NOUN
biomedich-730	72	21	signify	signify	VERB
biomedich-730	72	22	superior	superior	ADJ
biomedich-730	72	23	quality	quality	NOUN
biomedich-730	72	24	.	.	PUNCT
biomedich-730	73	1	errat	errat	PROPN
biomedich-730	73	2	also	also	ADV
biomedich-730	73	3	delivers	deliver	VERB
biomedich-730	73	4	results	result	NOUN
biomedich-730	73	5	with	with	ADP
biomedich-730	73	6	overall	overall	ADJ
biomedich-730	73	7	significance	significance	NOUN
biomedich-730	73	8	and	and	CCONJ
biomedich-730	73	9	quality	quality	NOUN
biomedich-730	73	10	,	,	PUNCT
biomedich-730	73	11	with	with	ADP
biomedich-730	73	12	a	a	DET
biomedich-730	73	13	widely	widely	ADV
biomedich-730	73	14	accepted	accept	VERB
biomedich-730	73	15	score	score	NOUN
biomedich-730	73	16	exceeding	exceed	VERB
biomedich-730	73	17	50	50	NUM
biomedich-730	73	18	,	,	PUNCT
biomedich-730	73	19	indicating	indicate	VERB
biomedich-730	73	20	a	a	DET
biomedich-730	73	21	stable	stable	ADJ
biomedich-730	73	22	protein	protein	NOUN
biomedich-730	73	23	(	(	PUNCT
biomedich-730	73	24	sumitha	sumitha	NOUN
biomedich-730	73	25	et	et	PROPN
biomedich-730	73	26	al	al	PROPN
biomedich-730	73	27	.	.	PROPN
biomedich-730	73	28	,	,	PUNCT
biomedich-730	73	29	2020	2020	NUM
biomedich-730	73	30	)	)	PUNCT
biomedich-730	73	31	.	.	PUNCT
biomedich-730	74	1	the	the	DET
biomedich-730	74	2	errat	errat	NOUN
biomedich-730	74	3	analysis	analysis	NOUN
biomedich-730	74	4	results	result	NOUN
biomedich-730	74	5	(	(	PUNCT
biomedich-730	74	6	figure	figure	NOUN
biomedich-730	74	7	2	2	NUM
biomedich-730	74	8	)	)	PUNCT
biomedich-730	74	9	indicated	indicate	VERB
biomedich-730	74	10	that	that	SCONJ
biomedich-730	74	11	the	the	DET
biomedich-730	74	12	quality	quality	NOUN
biomedich-730	74	13	factor	factor	NOUN
biomedich-730	74	14	values	value	NOUN
biomedich-730	74	15	were	be	AUX
biomedich-730	74	16	97.134	97.134	NUM
biomedich-730	74	17	%	%	NOUN
biomedich-730	74	18	for	for	ADP
biomedich-730	74	19	the	the	DET
biomedich-730	74	20	angiotensin	angiotensin	PROPN
biomedich-730	74	21	ii	ii	PROPN
biomedich-730	74	22	type-1	type-1	PROPN
biomedich-730	74	23	receptor	receptor	NOUN
biomedich-730	74	24	(	(	PUNCT
biomedich-730	74	25	at1r	at1r	NOUN
biomedich-730	74	26	)	)	PUNCT
biomedich-730	74	27	.	.	PUNCT
biomedich-730	75	1	the	the	DET
biomedich-730	75	2	outcome	outcome	NOUN
biomedich-730	75	3	of	of	ADP
biomedich-730	75	4	this	this	DET
biomedich-730	75	5	computation	computation	NOUN
biomedich-730	75	6	indicates	indicate	VERB
biomedich-730	75	7	that	that	SCONJ
biomedich-730	75	8	the	the	DET
biomedich-730	75	9	protein	protein	NOUN
biomedich-730	75	10	structure	structure	NOUN
biomedich-730	75	11	of	of	ADP
biomedich-730	75	12	the	the	DET
biomedich-730	75	13	angiotensin	angiotensin	NOUN
biomedich-730	75	14	ii	ii	PROPN
biomedich-730	75	15	type-1	type-1	PROPN
biomedich-730	75	16	receptor	receptor	NOUN
biomedich-730	75	17	(	(	PUNCT
biomedich-730	75	18	at1r	at1r	PROPN
biomedich-730	75	19	)	)	PUNCT
biomedich-730	75	20	,	,	PUNCT
biomedich-730	75	21	characterized	characterize	VERB
biomedich-730	75	22	by	by	ADP
biomedich-730	75	23	high	high	ADJ
biomedich-730	75	24	quality	quality	NOUN
biomedich-730	75	25	and	and	CCONJ
biomedich-730	75	26	high	high	ADJ
biomedich-730	75	27	resolution	resolution	NOUN
biomedich-730	75	28	.	.	PUNCT
biomedich-730	76	1	figure	figure	NOUN
biomedich-730	76	2	2	2	NUM
biomedich-730	76	3	.	.	PUNCT
biomedich-730	76	4	structure	structure	NOUN
biomedich-730	76	5	validation	validation	NOUN
biomedich-730	76	6	result	result	NOUN
biomedich-730	76	7	of	of	ADP
biomedich-730	76	8	the	the	DET
biomedich-730	76	9	errat	errat	NOUN
biomedich-730	76	10	tool	tool	NOUN
biomedich-730	76	11	.	.	PUNCT
biomedich-730	77	1	ramachandran	ramachandran	PROPN
biomedich-730	77	2	plots	plot	NOUN
biomedich-730	77	3	procheck	procheck	NOUN
biomedich-730	77	4	inspection	inspection	NOUN
biomedich-730	77	5	by	by	ADP
biomedich-730	77	6	ramachandran	ramachandran	NOUN
biomedich-730	77	7	plots	plot	NOUN
biomedich-730	77	8	(	(	PUNCT
biomedich-730	77	9	figure	figure	NOUN
biomedich-730	77	10	3	3	NUM
biomedich-730	77	11	.	.	PUNCT
biomedich-730	77	12	)	)	PUNCT
biomedich-730	77	13	focuses	focus	VERB
biomedich-730	77	14	on	on	ADP
biomedich-730	77	15	specific	specific	ADJ
biomedich-730	77	16	geometries	geometry	NOUN
biomedich-730	77	17	and	and	CCONJ
biomedich-730	77	18	allows	allow	VERB
biomedich-730	77	19	the	the	DET
biomedich-730	77	20	overall	overall	ADJ
biomedich-730	77	21	structure	structure	NOUN
biomedich-730	77	22	to	to	PART
biomedich-730	77	23	be	be	AUX
biomedich-730	77	24	evaluated	evaluate	VERB
biomedich-730	77	25	.	.	PUNCT
biomedich-730	78	1	the	the	DET
biomedich-730	78	2	ramachandran	ramachandran	PROPN
biomedich-730	78	3	plot	plot	NOUN
biomedich-730	78	4	illustrates	illustrate	VERB
biomedich-730	78	5	the	the	DET
biomedich-730	78	6	distribution	distribution	NOUN
biomedich-730	78	7	of	of	ADP
biomedich-730	78	8	the	the	DET
biomedich-730	78	9	torsional	torsional	NOUN
biomedich-730	78	10	angles	angle	VERB
biomedich-730	78	11	φ	φ	PROPN
biomedich-730	78	12	(	(	PUNCT
biomedich-730	78	13	phi	phi	NOUN
biomedich-730	78	14	)	)	PUNCT
biomedich-730	78	15	and	and	CCONJ
biomedich-730	78	16	ψ	ψ	X
biomedich-730	78	17	(	(	PUNCT
biomedich-730	78	18	psi	psi	NOUN
biomedich-730	78	19	)	)	PUNCT
biomedich-730	78	20	of	of	ADP
biomedich-730	78	21	the	the	DET
biomedich-730	78	22	protein	protein	NOUN
biomedich-730	78	23	's	's	PART
biomedich-730	78	24	main	main	ADJ
biomedich-730	78	25	chain	chain	NOUN
biomedich-730	78	26	.	.	PUNCT
biomedich-730	79	1	to	to	PART
biomedich-730	79	2	see	see	VERB
biomedich-730	79	3	if	if	SCONJ
biomedich-730	79	4	the	the	DET
biomedich-730	79	5	278	278	NUM
biomedich-730	79	6	biology	biology	NOUN
biomedich-730	79	7	,	,	PUNCT
biomedich-730	79	8	medicine	medicine	NOUN
biomedich-730	79	9	,	,	PUNCT
biomedich-730	79	10	&	&	CCONJ
biomedich-730	79	11	natural	natural	ADJ
biomedich-730	79	12	product	product	NOUN
biomedich-730	79	13	chemistry	chemistry	NOUN
biomedich-730	79	14	14	14	NUM
biomedich-730	79	15	(	(	PUNCT
biomedich-730	79	16	1	1	NUM
biomedich-730	79	17	)	)	PUNCT
biomedich-730	79	18	,	,	PUNCT
biomedich-730	79	19	2025	2025	NUM
biomedich-730	79	20	:	:	PUNCT
biomedich-730	79	21	275	275	NUM
biomedich-730	79	22	-	-	SYM
biomedich-730	79	23	282	282	NUM
biomedich-730	79	24	ramachandran	ramachandran	PROPN
biomedich-730	79	25	plot	plot	NOUN
biomedich-730	79	26	is	be	AUX
biomedich-730	79	27	good	good	ADJ
biomedich-730	79	28	for	for	ADP
biomedich-730	79	29	protein	protein	NOUN
biomedich-730	79	30	structure	structure	NOUN
biomedich-730	79	31	analysis	analysis	NOUN
biomedich-730	79	32	,	,	PUNCT
biomedich-730	79	33	it	it	PRON
biomedich-730	79	34	can	can	AUX
biomedich-730	79	35	be	be	AUX
biomedich-730	79	36	checked	check	VERB
biomedich-730	79	37	by	by	ADP
biomedich-730	79	38	plotting	plot	VERB
biomedich-730	79	39	non	non	ADJ
biomedich-730	79	40	-	-	ADJ
biomedich-730	79	41	glycine	glycine	ADJ
biomedich-730	79	42	residues	residue	NOUN
biomedich-730	79	43	in	in	ADP
biomedich-730	79	44	disallowed	disallow	VERB
biomedich-730	79	45	regions	region	NOUN
biomedich-730	79	46	less	less	ADJ
biomedich-730	79	47	than	than	ADP
biomedich-730	79	48	0.8	0.8	NUM
biomedich-730	79	49	%	%	NOUN
biomedich-730	79	50	(	(	PUNCT
biomedich-730	79	51	gunasekaran	gunasekaran	NOUN
biomedich-730	79	52	et	et	NOUN
biomedich-730	79	53	al	al	PROPN
biomedich-730	79	54	.	.	PROPN
biomedich-730	79	55	,	,	PUNCT
biomedich-730	79	56	1996	1996	NUM
biomedich-730	79	57	)	)	PUNCT
biomedich-730	79	58	.	.	PUNCT
biomedich-730	80	1	figure	figure	VERB
biomedich-730	80	2	3	3	NUM
biomedich-730	80	3	.	.	PUNCT
biomedich-730	81	1	the	the	DET
biomedich-730	81	2	ramachandran	ramachandran	PROPN
biomedich-730	81	3	procheck	procheck	PROPN
biomedich-730	81	4	determined	determine	VERB
biomedich-730	81	5	the	the	DET
biomedich-730	81	6	plot	plot	NOUN
biomedich-730	81	7	.	.	PUNCT
biomedich-730	82	1	red	red	PROPN
biomedich-730	82	2	represents	represent	VERB
biomedich-730	82	3	a	a	DET
biomedich-730	82	4	preferred	preferred	ADJ
biomedich-730	82	5	region	region	NOUN
biomedich-730	82	6	,	,	PUNCT
biomedich-730	82	7	yellow	yellow	ADJ
biomedich-730	82	8	indicates	indicate	VERB
biomedich-730	82	9	an	an	DET
biomedich-730	82	10	authorized	authorized	ADJ
biomedich-730	82	11	region	region	NOUN
biomedich-730	82	12	,	,	PUNCT
biomedich-730	82	13	bright	bright	ADJ
biomedich-730	82	14	yellow	yellow	NOUN
biomedich-730	82	15	suggests	suggest	VERB
biomedich-730	82	16	an	an	DET
biomedich-730	82	17	amino	amino	NOUN
biomedich-730	82	18	acid	acid	NOUN
biomedich-730	82	19	region	region	NOUN
biomedich-730	82	20	that	that	PRON
biomedich-730	82	21	is	be	AUX
biomedich-730	82	22	liberally	liberally	ADV
biomedich-730	82	23	allowed	allow	VERB
biomedich-730	82	24	,	,	PUNCT
biomedich-730	82	25	and	and	CCONJ
biomedich-730	82	26	white	white	ADJ
biomedich-730	82	27	indicates	indicate	VERB
biomedich-730	82	28	a	a	DET
biomedich-730	82	29	banned	ban	VERB
biomedich-730	82	30	region	region	NOUN
biomedich-730	82	31	.	.	PUNCT
biomedich-730	83	1	the	the	DET
biomedich-730	83	2	results	result	NOUN
biomedich-730	83	3	show	show	VERB
biomedich-730	83	4	that	that	SCONJ
biomedich-730	83	5	87.5	87.5	NUM
biomedich-730	83	6	%	%	NOUN
biomedich-730	83	7	of	of	ADP
biomedich-730	83	8	the	the	DET
biomedich-730	83	9	residues	residue	NOUN
biomedich-730	83	10	are	be	AUX
biomedich-730	83	11	in	in	ADP
biomedich-730	83	12	the	the	DET
biomedich-730	83	13	most	most	ADV
biomedich-730	83	14	favorable	favorable	ADJ
biomedich-730	83	15	region	region	NOUN
biomedich-730	83	16	,	,	PUNCT
biomedich-730	83	17	which	which	PRON
biomedich-730	83	18	indicates	indicate	VERB
biomedich-730	83	19	adequate	adequate	ADJ
biomedich-730	83	20	structural	structural	ADJ
biomedich-730	83	21	stability	stability	NOUN
biomedich-730	83	22	.	.	PUNCT
biomedich-730	84	1	8.5	8.5	NUM
biomedich-730	84	2	%	%	NOUN
biomedich-730	84	3	of	of	ADP
biomedich-730	84	4	the	the	DET
biomedich-730	84	5	residues	residue	NOUN
biomedich-730	84	6	were	be	AUX
biomedich-730	84	7	in	in	ADP
biomedich-730	84	8	the	the	DET
biomedich-730	84	9	additional	additional	ADJ
biomedich-730	84	10	allowed	allow	VERB
biomedich-730	84	11	region	region	NOUN
biomedich-730	84	12	,	,	PUNCT
biomedich-730	84	13	and	and	CCONJ
biomedich-730	84	14	3.4	3.4	NUM
biomedich-730	84	15	%	%	NOUN
biomedich-730	84	16	were	be	AUX
biomedich-730	84	17	in	in	ADP
biomedich-730	84	18	the	the	DET
biomedich-730	84	19	general	general	ADJ
biomedich-730	84	20	allowed	allow	VERB
biomedich-730	84	21	region	region	NOUN
biomedich-730	84	22	.	.	PUNCT
biomedich-730	85	1	0.6	0.6	NUM
biomedich-730	85	2	%	%	NOUN
biomedich-730	85	3	of	of	ADP
biomedich-730	85	4	the	the	DET
biomedich-730	85	5	residuals	residual	NOUN
biomedich-730	85	6	were	be	AUX
biomedich-730	85	7	in	in	ADP
biomedich-730	85	8	the	the	DET
biomedich-730	85	9	nonallowed	nonallowe	VERB
biomedich-730	85	10	region	region	NOUN
biomedich-730	85	11	,	,	PUNCT
biomedich-730	85	12	indicating	indicate	VERB
biomedich-730	85	13	potential	potential	ADJ
biomedich-730	85	14	local	local	ADJ
biomedich-730	85	15	instability	instability	NOUN
biomedich-730	85	16	or	or	CCONJ
biomedich-730	85	17	possible	possible	ADJ
biomedich-730	85	18	modeling	modeling	NOUN
biomedich-730	85	19	errors	error	NOUN
biomedich-730	85	20	.	.	PUNCT
biomedich-730	86	1	overall	overall	ADV
biomedich-730	86	2	,	,	PUNCT
biomedich-730	86	3	the	the	DET
biomedich-730	86	4	structure	structure	NOUN
biomedich-730	86	5	is	be	AUX
biomedich-730	86	6	close	close	ADJ
biomedich-730	86	7	to	to	ADP
biomedich-730	86	8	the	the	DET
biomedich-730	86	9	criteria	criterion	NOUN
biomedich-730	86	10	of	of	ADP
biomedich-730	86	11	a	a	DET
biomedich-730	86	12	high	high	ADJ
biomedich-730	86	13	-	-	PUNCT
biomedich-730	86	14	quality	quality	NOUN
biomedich-730	86	15	model	model	NOUN
biomedich-730	86	16	,	,	PUNCT
biomedich-730	86	17	although	although	SCONJ
biomedich-730	86	18	further	further	ADJ
biomedich-730	86	19	refinements	refinement	NOUN
biomedich-730	86	20	may	may	AUX
biomedich-730	86	21	be	be	AUX
biomedich-730	86	22	needed	need	VERB
biomedich-730	86	23	to	to	PART
biomedich-730	86	24	improve	improve	VERB
biomedich-730	86	25	its	its	PRON
biomedich-730	86	26	validity	validity	NOUN
biomedich-730	86	27	.	.	PUNCT
biomedich-730	87	1	molecular	molecular	ADJ
biomedich-730	87	2	docking	docking	NOUN
biomedich-730	87	3	docking	docking	NOUN
biomedich-730	87	4	was	be	AUX
biomedich-730	87	5	conducted	conduct	VERB
biomedich-730	87	6	on	on	ADP
biomedich-730	87	7	one	one	NUM
biomedich-730	87	8	active	active	ADJ
biomedich-730	87	9	compound	compound	NOUN
biomedich-730	87	10	of	of	ADP
biomedich-730	87	11	ocimum	ocimum	ADJ
biomedich-730	87	12	basilicum	basilicum	NOUN
biomedich-730	87	13	with	with	ADP
biomedich-730	87	14	the	the	DET
biomedich-730	87	15	at1r	at1r	PROPN
biomedich-730	87	16	receptor	receptor	NOUN
biomedich-730	87	17	,	,	PUNCT
biomedich-730	87	18	utilizing	utilize	VERB
biomedich-730	87	19	eprosartan	eprosartan	PROPN
biomedich-730	87	20	,	,	PUNCT
biomedich-730	87	21	azilsartan	azilsartan	ADJ
biomedich-730	87	22	,	,	PUNCT
biomedich-730	87	23	irbesartan	irbesartan	PROPN
biomedich-730	87	24	,	,	PUNCT
biomedich-730	87	25	telmisartan	telmisartan	PROPN
biomedich-730	87	26	,	,	PUNCT
biomedich-730	87	27	valsartan	valsartan	PROPN
biomedich-730	87	28	,	,	PUNCT
biomedich-730	87	29	losartan	losartan	PROPN
biomedich-730	87	30	,	,	PUNCT
biomedich-730	87	31	olmesartan	olmesartan	PROPN
biomedich-730	87	32	,	,	PUNCT
biomedich-730	87	33	and	and	CCONJ
biomedich-730	87	34	candesartan	candesartan	PROPN
biomedich-730	87	35	ligands	ligand	NOUN
biomedich-730	87	36	for	for	ADP
biomedich-730	87	37	comparison	comparison	NOUN
biomedich-730	87	38	.	.	PUNCT
biomedich-730	88	1	docking	docking	NOUN
biomedich-730	88	2	is	be	AUX
biomedich-730	88	3	performed	perform	VERB
biomedich-730	88	4	using	use	VERB
biomedich-730	88	5	the	the	DET
biomedich-730	88	6	pyrx	pyrx	NOUN
biomedich-730	88	7	,	,	PUNCT
biomedich-730	88	8	autodock	autodock	NOUN
biomedich-730	88	9	,	,	PUNCT
biomedich-730	88	10	and	and	CCONJ
biomedich-730	88	11	vina	vina	PROPN
biomedich-730	88	12	software	software	PROPN
biomedich-730	88	13	,	,	PUNCT
biomedich-730	88	14	followed	follow	VERB
biomedich-730	88	15	by	by	ADP
biomedich-730	88	16	the	the	DET
biomedich-730	88	17	configuration	configuration	NOUN
biomedich-730	88	18	of	of	ADP
biomedich-730	88	19	the	the	DET
biomedich-730	88	20	grid	grid	NOUN
biomedich-730	88	21	box	box	NOUN
biomedich-730	88	22	.	.	PUNCT
biomedich-730	89	1	the	the	DET
biomedich-730	89	2	binding	bind	VERB
biomedich-730	89	3	affinity	affinity	NOUN
biomedich-730	89	4	served	serve	VERB
biomedich-730	89	5	as	as	ADP
biomedich-730	89	6	the	the	DET
biomedich-730	89	7	primary	primary	ADJ
biomedich-730	89	8	criterion	criterion	NOUN
biomedich-730	89	9	for	for	ADP
biomedich-730	89	10	assessing	assess	VERB
biomedich-730	89	11	the	the	DET
biomedich-730	89	12	quality	quality	NOUN
biomedich-730	89	13	of	of	ADP
biomedich-730	89	14	the	the	DET
biomedich-730	89	15	molecular	molecular	ADJ
biomedich-730	89	16	docking	docking	NOUN
biomedich-730	89	17	outcomes	outcome	NOUN
biomedich-730	89	18	(	(	PUNCT
biomedich-730	89	19	agu	agu	NOUN
biomedich-730	89	20	et	et	PROPN
biomedich-730	89	21	al	al	PROPN
biomedich-730	89	22	.	.	PROPN
biomedich-730	89	23	,	,	PUNCT
biomedich-730	89	24	2023	2023	NUM
biomedich-730	89	25	)	)	PUNCT
biomedich-730	89	26	.	.	PUNCT
biomedich-730	90	1	the	the	DET
biomedich-730	90	2	results	result	NOUN
biomedich-730	90	3	indicated	indicate	VERB
biomedich-730	90	4	that	that	SCONJ
biomedich-730	90	5	the	the	DET
biomedich-730	90	6	natural	natural	ADJ
biomedich-730	90	7	ligands	ligand	NOUN
biomedich-730	90	8	of	of	ADP
biomedich-730	90	9	flavonoids	flavonoid	NOUN
biomedich-730	90	10	indicate	indicate	VERB
biomedich-730	90	11	spontaneous	spontaneous	ADJ
biomedich-730	90	12	binding	binding	NOUN
biomedich-730	90	13	to	to	ADP
biomedich-730	90	14	the	the	DET
biomedich-730	90	15	type-1	type-1	PROPN
biomedich-730	90	16	angiotensin	angiotensin	NOUN
biomedich-730	90	17	ii	ii	PROPN
biomedich-730	90	18	receptor	receptor	NOUN
biomedich-730	90	19	,	,	PUNCT
biomedich-730	90	20	showing	show	VERB
biomedich-730	90	21	a	a	DET
biomedich-730	90	22	binding	bind	VERB
biomedich-730	90	23	affinity	affinity	NOUN
biomedich-730	90	24	of	of	ADP
biomedich-730	90	25	-8.8	-8.8	PROPN
biomedich-730	90	26	kcal	kcal	PROPN
biomedich-730	90	27	/	/	SYM
biomedich-730	90	28	mol	mol	PROPN
biomedich-730	90	29	.	.	PUNCT
biomedich-730	91	1	in	in	ADP
biomedich-730	91	2	comparison	comparison	NOUN
biomedich-730	91	3	,	,	PUNCT
biomedich-730	91	4	the	the	DET
biomedich-730	91	5	binding	bind	VERB
biomedich-730	91	6	affinities	affinity	NOUN
biomedich-730	91	7	of	of	ADP
biomedich-730	91	8	the	the	DET
biomedich-730	91	9	following	follow	VERB
biomedich-730	91	10	agents	agent	NOUN
biomedich-730	91	11	are	be	AUX
biomedich-730	91	12	as	as	SCONJ
biomedich-730	91	13	follows	follow	VERB
biomedich-730	91	14	:	:	PUNCT
biomedich-730	92	1	valsartan	valsartan	PROPN
biomedich-730	92	2	-6.8	-6.8	PROPN
biomedich-730	92	3	kcal	kcal	PROPN
biomedich-730	92	4	/	/	SYM
biomedich-730	92	5	mol	mol	PROPN
biomedich-730	92	6	,	,	PUNCT
biomedich-730	92	7	eprosartan	eprosartan	PROPN
biomedich-730	92	8	-8.2	-8.2	PROPN
biomedich-730	92	9	kcal	kcal	PROPN
biomedich-730	92	10	/	/	SYM
biomedich-730	92	11	mol	mol	PROPN
biomedich-730	92	12	,	,	PUNCT
biomedich-730	92	13	losartan	losartan	ADJ
biomedich-730	92	14	-8.5	-8.5	INTJ
biomedich-730	92	15	kcal	kcal	PROPN
biomedich-730	92	16	/	/	SYM
biomedich-730	92	17	mol	mol	PROPN
biomedich-730	92	18	,	,	PUNCT
biomedich-730	92	19	olmesartan	olmesartan	PROPN
biomedich-730	92	20	-9.5	-9.5	PROPN
biomedich-730	92	21	kcal	kcal	PROPN
biomedich-730	92	22	/	/	SYM
biomedich-730	92	23	mol	mol	PROPN
biomedich-730	92	24	,	,	PUNCT
biomedich-730	92	25	irbesartan	irbesartan	PROPN
biomedich-730	92	26	-9.9	-9.9	PUNCT
biomedich-730	92	27	kcal	kcal	PROPN
biomedich-730	92	28	/	/	SYM
biomedich-730	92	29	mol	mol	PROPN
biomedich-730	92	30	,	,	PUNCT
biomedich-730	92	31	candesartan	candesartan	PROPN
biomedich-730	92	32	-10.2	-10.2	PROPN
biomedich-730	92	33	kcal	kcal	PROPN
biomedich-730	92	34	/	/	SYM
biomedich-730	92	35	mol	mol	PROPN
biomedich-730	92	36	,	,	PUNCT
biomedich-730	92	37	azilsartan	azilsartan	PROPN
biomedich-730	92	38	-10.4	-10.4	NUM
biomedich-730	92	39	kcal	kcal	PROPN
biomedich-730	92	40	/	/	SYM
biomedich-730	92	41	mol	mol	PROPN
biomedich-730	92	42	,	,	PUNCT
biomedich-730	92	43	and	and	CCONJ
biomedich-730	92	44	telmisartan	telmisartan	PROPN
biomedich-730	92	45	-11.2	-11.2	PROPN
biomedich-730	92	46	kcal	kcal	PROPN
biomedich-730	92	47	/	/	SYM
biomedich-730	92	48	mol	mol	PROPN
biomedich-730	92	49	(	(	PUNCT
biomedich-730	92	50	table	table	NOUN
biomedich-730	92	51	1	1	NUM
biomedich-730	92	52	)	)	PUNCT
biomedich-730	92	53	.	.	PUNCT
biomedich-730	93	1	molecular	molecular	ADJ
biomedich-730	93	2	docking	docking	NOUN
biomedich-730	93	3	results	result	NOUN
biomedich-730	93	4	indicate	indicate	VERB
biomedich-730	93	5	that	that	SCONJ
biomedich-730	93	6	ocimum	ocimum	PROPN
biomedich-730	93	7	basilicum	basilicum	PROPN
biomedich-730	93	8	possesses	possess	VERB
biomedich-730	93	9	the	the	DET
biomedich-730	93	10	potential	potential	NOUN
biomedich-730	93	11	to	to	PART
biomedich-730	93	12	treat	treat	VERB
biomedich-730	93	13	hypertension	hypertension	NOUN
biomedich-730	93	14	.	.	PUNCT
biomedich-730	94	1	table	table	NOUN
biomedich-730	94	2	1	1	NUM
biomedich-730	94	3	.	.	PUNCT
biomedich-730	94	4	result	result	NOUN
biomedich-730	94	5	of	of	ADP
biomedich-730	94	6	molecular	molecular	ADJ
biomedich-730	94	7	docking	docking	NOUN
biomedich-730	94	8	simulation	simulation	NOUN
biomedich-730	94	9	of	of	ADP
biomedich-730	94	10	ligands	ligand	NOUN
biomedich-730	94	11	against	against	ADP
biomedich-730	94	12	at1r	at1r	PROPN
biomedich-730	94	13	.	.	PUNCT
biomedich-730	95	1	ligands	ligand	NOUN
biomedich-730	95	2	cid	cid	VERB
biomedich-730	95	3	molecular	molecular	ADJ
biomedich-730	95	4	formula	formula	NOUN
biomedich-730	95	5	molecular	molecular	ADJ
biomedich-730	95	6	weight	weight	NOUN
biomedich-730	95	7	(	(	PUNCT
biomedich-730	95	8	g	g	NOUN
biomedich-730	95	9	/	/	SYM
biomedich-730	95	10	mol	mol	NOUN
biomedich-730	95	11	)	)	PUNCT
biomedich-730	95	12	binding	bind	VERB
biomedich-730	95	13	affinity	affinity	NOUN
biomedich-730	95	14	(	(	PUNCT
biomedich-730	95	15	kcal	kcal	NOUN
biomedich-730	95	16	/	/	SYM
biomedich-730	95	17	mol	mol	NOUN
biomedich-730	95	18	)	)	PUNCT
biomedich-730	95	19	flavonoids	flavonoid	NOUN
biomedich-730	95	20	5281616	5281616	NUM
biomedich-730	95	21	c15h10o5	c15h10o5	PROPN
biomedich-730	95	22	270.24	270.24	NUM
biomedich-730	95	23	-8.8	-8.8	ADV
biomedich-730	95	24	valsartan	valsartan	PROPN
biomedich-730	95	25	60846	60846	NUM
biomedich-730	95	26	c24h29n5o3	c24h29n5o3	PROPN
biomedich-730	95	27	435.5	435.5	NUM
biomedich-730	95	28	-6.8	-6.8	PROPN
biomedich-730	95	29	eprosartan	eprosartan	PROPN
biomedich-730	95	30	5281037	5281037	NUM
biomedich-730	95	31	c23h24n2o4s	c23h24n2o4s	PROPN
biomedich-730	96	1	424.5	424.5	NUM
biomedich-730	96	2	-8.2	-8.2	PROPN
biomedich-730	96	3	losartan	losartan	ADJ
biomedich-730	96	4	3961	3961	NUM
biomedich-730	96	5	c24h26n6o3	c24h26n6o3	PROPN
biomedich-730	96	6	446.5	446.5	NUM
biomedich-730	96	7	-9.5	-9.5	NOUN
biomedich-730	96	8	olmesartan	olmesartan	PROPN
biomedich-730	96	9	158781	158781	NUM
biomedich-730	96	10	c24h26n6o3	c24h26n6o3	PROPN
biomedich-730	96	11	446.5	446.5	NUM
biomedich-730	96	12	-9.5	-9.5	NOUN
biomedich-730	96	13	irbesartan	irbesartan	PROPN
biomedich-730	96	14	3749	3749	NUM
biomedich-730	96	15	c25h28n6o	c25h28n6o	NOUN
biomedich-730	96	16	428.5	428.5	NUM
biomedich-730	96	17	-9.9	-9.9	PUNCT
biomedich-730	96	18	candesartan	candesartan	PROPN
biomedich-730	96	19	2541	2541	NUM
biomedich-730	96	20	c24h20n6o3	c24h20n6o3	PROPN
biomedich-730	97	1	440.5	440.5	NUM
biomedich-730	97	2	-10.2	-10.2	PROPN
biomedich-730	97	3	azilsartan	azilsartan	ADJ
biomedich-730	97	4	135415867	135415867	NUM
biomedich-730	97	5	c25h20n4o5	c25h20n4o5	PROPN
biomedich-730	97	6	456.4	456.4	NUM
biomedich-730	97	7	-10.4	-10.4	NUM
biomedich-730	97	8	telmisartan	telmisartan	PROPN
biomedich-730	97	9	65999	65999	NUM
biomedich-730	97	10	c33h30n4o2	c33h30n4o2	PROPN
biomedich-730	97	11	514.6	514.6	NUM
biomedich-730	97	12	-11.2	-11.2	PUNCT
biomedich-730	97	13	post	post	ADJ
biomedich-730	97	14	-	-	ADJ
biomedich-730	97	15	docking	docking	ADJ
biomedich-730	97	16	analysis	analysis	NOUN
biomedich-730	98	1	the	the	DET
biomedich-730	98	2	molecular	molecular	ADJ
biomedich-730	98	3	docking	docking	NOUN
biomedich-730	98	4	results	result	NOUN
biomedich-730	98	5	generated	generate	VERB
biomedich-730	98	6	by	by	ADP
biomedich-730	98	7	pyrx	pyrx	NOUN
biomedich-730	98	8	software	software	NOUN
biomedich-730	98	9	will	will	AUX
biomedich-730	98	10	be	be	AUX
biomedich-730	98	11	subsequently	subsequently	ADV
biomedich-730	98	12	visualized	visualize	VERB
biomedich-730	98	13	with	with	ADP
biomedich-730	98	14	pymol	pymol	PROPN
biomedich-730	98	15	to	to	PART
biomedich-730	98	16	assess	assess	VERB
biomedich-730	98	17	the	the	DET
biomedich-730	98	18	ligand	ligand	NOUN
biomedich-730	98	19	's	's	PART
biomedich-730	98	20	positioning	positioning	NOUN
biomedich-730	98	21	within	within	ADP
biomedich-730	98	22	the	the	DET
biomedich-730	98	23	receptor	receptor	NOUN
biomedich-730	98	24	's	's	PART
biomedich-730	98	25	active	active	ADJ
biomedich-730	98	26	site	site	NOUN
biomedich-730	98	27	.	.	PUNCT
biomedich-730	99	1	this	this	DET
biomedich-730	99	2	visualization	visualization	NOUN
biomedich-730	99	3	attempts	attempt	VERB
biomedich-730	99	4	to	to	PART
biomedich-730	99	5	identify	identify	VERB
biomedich-730	99	6	significant	significant	ADJ
biomedich-730	99	7	interactions	interaction	NOUN
biomedich-730	99	8	between	between	ADP
biomedich-730	99	9	the	the	DET
biomedich-730	99	10	ligand	ligand	ADJ
biomedich-730	99	11	and	and	CCONJ
biomedich-730	99	12	essential	essential	ADJ
biomedich-730	99	13	residues	residue	NOUN
biomedich-730	99	14	on	on	ADP
biomedich-730	99	15	the	the	DET
biomedich-730	99	16	receptor	receptor	NOUN
biomedich-730	99	17	.	.	PUNCT
biomedich-730	100	1	furthermore	furthermore	ADV
biomedich-730	100	2	,	,	PUNCT
biomedich-730	100	3	an	an	DET
biomedich-730	100	4	analysis	analysis	NOUN
biomedich-730	100	5	of	of	ADP
biomedich-730	100	6	particular	particular	ADJ
biomedich-730	100	7	interactions	interaction	NOUN
biomedich-730	100	8	,	,	PUNCT
biomedich-730	100	9	including	include	VERB
biomedich-730	100	10	hydrogen	hydrogen	NOUN
biomedich-730	100	11	bonds	bond	NOUN
biomedich-730	100	12	,	,	PUNCT
biomedich-730	100	13	hydrophobic	hydrophobic	NOUN
biomedich-730	100	14	interactions	interaction	NOUN
biomedich-730	100	15	,	,	PUNCT
biomedich-730	100	16	and	and	CCONJ
biomedich-730	100	17	various	various	ADJ
biomedich-730	100	18	bond	bond	NOUN
biomedich-730	100	19	types	type	NOUN
biomedich-730	100	20	,	,	PUNCT
biomedich-730	100	21	will	will	AUX
biomedich-730	100	22	be	be	AUX
biomedich-730	100	23	conducted	conduct	VERB
biomedich-730	100	24	utilizing	utilize	VERB
biomedich-730	100	25	the	the	DET
biomedich-730	100	26	proteinplus	proteinplus	ADJ
biomedich-730	100	27	website	website	NOUN
biomedich-730	100	28	,	,	PUNCT
biomedich-730	100	29	which	which	PRON
biomedich-730	100	30	offers	offer	VERB
biomedich-730	100	31	comprehensive	comprehensive	ADJ
biomedich-730	100	32	information	information	NOUN
biomedich-730	100	33	on	on	ADP
biomedich-730	100	34	residues	residue	NOUN
biomedich-730	100	35	involved	involve	VERB
biomedich-730	100	36	in	in	ADP
biomedich-730	100	37	ligand	ligand	NOUN
biomedich-730	100	38	-	-	PUNCT
biomedich-730	100	39	receptor	receptor	NOUN
biomedich-730	100	40	interactions	interaction	NOUN
biomedich-730	100	41	.	.	PUNCT
biomedich-730	101	1	according	accord	VERB
biomedich-730	101	2	to	to	ADP
biomedich-730	101	3	the	the	DET
biomedich-730	101	4	photos	photo	NOUN
biomedich-730	101	5	provided	provide	VERB
biomedich-730	101	6	above	above	ADV
biomedich-730	101	7	,	,	PUNCT
biomedich-730	101	8	the	the	DET
biomedich-730	101	9	interactions	interaction	NOUN
biomedich-730	101	10	depicted	depict	VERB
biomedich-730	101	11	in	in	ADP
biomedich-730	101	12	each	each	DET
biomedich-730	101	13	image	image	NOUN
biomedich-730	101	14	are	be	AUX
biomedich-730	101	15	as	as	SCONJ
biomedich-730	101	16	follows	follow	VERB
biomedich-730	101	17	:	:	PUNCT
biomedich-730	101	18	figure	figure	VERB
biomedich-730	101	19	a	a	PRON
biomedich-730	101	20	illustrates	illustrate	VERB
biomedich-730	101	21	hydrogen	hydrogen	NOUN
biomedich-730	101	22	bonds	bond	NOUN
biomedich-730	101	23	between	between	ADP
biomedich-730	101	24	tyr	tyr	PROPN
biomedich-730	101	25	(	(	PUNCT
biomedich-730	101	26	hydroxyl	hydroxyl	NOUN
biomedich-730	101	27	)	)	PUNCT
biomedich-730	101	28	and	and	CCONJ
biomedich-730	101	29	arg	arg	NOUN
biomedich-730	101	30	residues	residue	NOUN
biomedich-730	101	31	,	,	PUNCT
biomedich-730	101	32	alongside	alongside	ADP
biomedich-730	101	33	π	π	PROPN
biomedich-730	101	34	-	-	PUNCT
biomedich-730	101	35	π	π	PROPN
biomedich-730	101	36	interactions	interaction	NOUN
biomedich-730	101	37	involving	involve	VERB
biomedich-730	101	38	the	the	DET
biomedich-730	101	39	aromatic	aromatic	ADJ
biomedich-730	101	40	rings	ring	NOUN
biomedich-730	101	41	of	of	ADP
biomedich-730	101	42	trp	trp	PROPN
biomedich-730	101	43	and	and	CCONJ
biomedich-730	101	44	tyr	tyr	PROPN
biomedich-730	101	45	residues	residue	NOUN
biomedich-730	101	46	.	.	PUNCT
biomedich-730	102	1	figure	figure	NOUN
biomedich-730	102	2	b	b	PROPN
biomedich-730	102	3	illustrates	illustrate	VERB
biomedich-730	102	4	hydrogen	hydrogen	NOUN
biomedich-730	102	5	connections	connection	NOUN
biomedich-730	102	6	between	between	ADP
biomedich-730	102	7	the	the	DET
biomedich-730	102	8	ligand	ligand	NOUN
biomedich-730	102	9	and	and	CCONJ
biomedich-730	102	10	arginine	arginine	NOUN
biomedich-730	102	11	residues	residue	NOUN
biomedich-730	102	12	,	,	PUNCT
biomedich-730	102	13	and	and	CCONJ
biomedich-730	102	14	hydrophobic	hydrophobic	NOUN
biomedich-730	102	15	interactions	interaction	NOUN
biomedich-730	102	16	between	between	ADP
biomedich-730	102	17	the	the	DET
biomedich-730	102	18	ligand	ligand	NOUN
biomedich-730	102	19	's	's	PART
biomedich-730	102	20	aromatic	aromatic	ADJ
biomedich-730	102	21	ring	ring	NOUN
biomedich-730	102	22	and	and	CCONJ
biomedich-730	102	23	aromatic	aromatic	ADJ
biomedich-730	102	24	residues	residue	NOUN
biomedich-730	102	25	.	.	PUNCT
biomedich-730	103	1	figure	figure	NOUN
biomedich-730	103	2	c	c	PROPN
biomedich-730	103	3	illustrates	illustrate	VERB
biomedich-730	103	4	a	a	DET
biomedich-730	103	5	hydrogen	hydrogen	NOUN
biomedich-730	103	6	bond	bond	NOUN
biomedich-730	103	7	with	with	ADP
biomedich-730	103	8	the	the	DET
biomedich-730	103	9	tyr	tyr	PROPN
biomedich-730	103	10	residue	residue	NOUN
biomedich-730	103	11	and	and	CCONJ
biomedich-730	103	12	a	a	DET
biomedich-730	103	13	π	π	PROPN
biomedich-730	103	14	-	-	PUNCT
biomedich-730	103	15	π	π	ADJ
biomedich-730	103	16	contact	contact	NOUN
biomedich-730	103	17	between	between	ADP
biomedich-730	103	18	the	the	DET
biomedich-730	103	19	aromatic	aromatic	ADJ
biomedich-730	103	20	ring	ring	NOUN
biomedich-730	103	21	of	of	ADP
biomedich-730	103	22	the	the	DET
biomedich-730	103	23	residue	residue	NOUN
biomedich-730	103	24	and	and	CCONJ
biomedich-730	103	25	the	the	DET
biomedich-730	103	26	ligand	ligand	NOUN
biomedich-730	103	27	.	.	PUNCT
biomedich-730	104	1	figure	figure	NOUN
biomedich-730	104	2	d	d	PROPN
biomedich-730	104	3	illustrates	illustrate	VERB
biomedich-730	104	4	hydrogen	hydrogen	NOUN
biomedich-730	104	5	bonds	bond	NOUN
biomedich-730	104	6	with	with	ADP
biomedich-730	104	7	tyr	tyr	PROPN
biomedich-730	104	8	and	and	CCONJ
biomedich-730	104	9	val	val	NOUN
biomedich-730	104	10	residues	residue	NOUN
biomedich-730	104	11	,	,	PUNCT
biomedich-730	104	12	along	along	ADP
biomedich-730	104	13	with	with	ADP
biomedich-730	104	14	π	π	PROPN
biomedich-730	104	15	-	-	PUNCT
biomedich-730	104	16	π	π	ADJ
biomedich-730	104	17	interactions	interaction	NOUN
biomedich-730	104	18	involving	involve	VERB
biomedich-730	104	19	trp	trp	PROPN
biomedich-730	104	20	residues	residue	NOUN
biomedich-730	104	21	.	.	PUNCT
biomedich-730	105	1	figure	figure	NOUN
biomedich-730	105	2	e	e	PROPN
biomedich-730	105	3	illustrates	illustrate	VERB
biomedich-730	105	4	the	the	DET
biomedich-730	105	5	interaction	interaction	NOUN
biomedich-730	105	6	comprising	comprise	VERB
biomedich-730	105	7	hydrogen	hydrogen	NOUN
biomedich-730	105	8	bonds	bond	NOUN
biomedich-730	105	9	with	with	ADP
biomedich-730	105	10	ser	ser	NOUN
biomedich-730	105	11	and	and	CCONJ
biomedich-730	105	12	phe	phe	NOUN
biomedich-730	105	13	residues	residue	NOUN
biomedich-730	105	14	,	,	PUNCT
biomedich-730	105	15	as	as	ADV
biomedich-730	105	16	well	well	ADV
biomedich-730	105	17	as	as	ADP
biomedich-730	105	18	thalib	thalib	PROPN
biomedich-730	105	19	&	&	CCONJ
biomedich-730	105	20	damayanti	damayanti	PROPN
biomedich-730	105	21	–	–	PUNCT
biomedich-730	105	22	in	in	ADP
biomedich-730	105	23	silico	silico	NOUN
biomedich-730	105	24	analysis	analysis	NOUN
biomedich-730	105	25	of	of	ADP
biomedich-730	105	26	ocimum	ocimum	ADJ
biomedich-730	105	27	basilicum	basilicum	NOUN
biomedich-730	105	28	flavonoids	flavonoid	NOUN
biomedich-730	105	29	as	as	ADP
biomedich-730	105	30	…	…	PUNCT
biomedich-730	105	31	279	279	NUM
biomedich-730	105	32	hydrophobic	hydrophobic	NOUN
biomedich-730	105	33	interactions	interaction	NOUN
biomedich-730	105	34	between	between	ADP
biomedich-730	105	35	the	the	DET
biomedich-730	105	36	ligand	ligand	ADJ
biomedich-730	105	37	and	and	CCONJ
biomedich-730	105	38	aromatic	aromatic	ADJ
biomedich-730	105	39	residues	residue	NOUN
biomedich-730	105	40	.	.	PUNCT
biomedich-730	106	1	image	image	NOUN
biomedich-730	106	2	f	f	PROPN
biomedich-730	106	3	depicts	depict	VERB
biomedich-730	106	4	hydrogen	hydrogen	NOUN
biomedich-730	106	5	bonding	bonding	NOUN
biomedich-730	106	6	with	with	ADP
biomedich-730	106	7	the	the	DET
biomedich-730	106	8	tyrosine	tyrosine	NOUN
biomedich-730	106	9	residue	residue	NOUN
biomedich-730	106	10	and	and	CCONJ
biomedich-730	106	11	hydrophobic	hydrophobic	NOUN
biomedich-730	106	12	contact	contact	NOUN
biomedich-730	106	13	with	with	ADP
biomedich-730	106	14	the	the	DET
biomedich-730	106	15	residue	residue	NOUN
biomedich-730	106	16	's	's	PART
biomedich-730	106	17	aromatic	aromatic	ADJ
biomedich-730	106	18	ring	ring	NOUN
biomedich-730	106	19	.	.	PUNCT
biomedich-730	107	1	figure	figure	NOUN
biomedich-730	107	2	g	g	PROPN
biomedich-730	107	3	illustrates	illustrate	VERB
biomedich-730	107	4	hydrogen	hydrogen	NOUN
biomedich-730	107	5	bonding	bonding	NOUN
biomedich-730	107	6	with	with	ADP
biomedich-730	107	7	thr	thr	PROPN
biomedich-730	107	8	and	and	CCONJ
biomedich-730	107	9	tyr	tyr	PROPN
biomedich-730	107	10	residues	residue	NOUN
biomedich-730	107	11	,	,	PUNCT
biomedich-730	107	12	together	together	ADV
biomedich-730	107	13	with	with	ADP
biomedich-730	107	14	π	π	PROPN
biomedich-730	107	15	-	-	PUNCT
biomedich-730	107	16	π	π	ADJ
biomedich-730	107	17	interactions	interaction	NOUN
biomedich-730	107	18	involving	involve	VERB
biomedich-730	107	19	aromatic	aromatic	ADJ
biomedich-730	107	20	residues	residue	NOUN
biomedich-730	107	21	.	.	PUNCT
biomedich-730	108	1	in	in	ADP
biomedich-730	108	2	figure	figure	NOUN
biomedich-730	108	3	h	h	NOUN
biomedich-730	108	4	,	,	PUNCT
biomedich-730	108	5	interactions	interaction	NOUN
biomedich-730	108	6	comprise	comprise	VERB
biomedich-730	108	7	hydrogen	hydrogen	NOUN
biomedich-730	108	8	bonds	bond	NOUN
biomedich-730	108	9	with	with	ADP
biomedich-730	108	10	aspartate	aspartate	NOUN
biomedich-730	108	11	residues	residue	NOUN
biomedich-730	108	12	and	and	CCONJ
biomedich-730	108	13	π	π	NOUN
biomedich-730	108	14	-	-	PUNCT
biomedich-730	108	15	π	π	ADJ
biomedich-730	108	16	interactions	interaction	NOUN
biomedich-730	108	17	between	between	ADP
biomedich-730	108	18	the	the	DET
biomedich-730	108	19	ligand	ligand	ADJ
biomedich-730	108	20	and	and	CCONJ
biomedich-730	108	21	aromatic	aromatic	ADJ
biomedich-730	108	22	residues	residue	NOUN
biomedich-730	108	23	.	.	PUNCT
biomedich-730	109	1	ultimately	ultimately	ADV
biomedich-730	109	2	,	,	PUNCT
biomedich-730	109	3	in	in	ADP
biomedich-730	109	4	figure	figure	NOUN
biomedich-730	109	5	i	i	PRON
biomedich-730	109	6	,	,	PUNCT
biomedich-730	109	7	hydrogen	hydrogen	NOUN
biomedich-730	109	8	bonds	bond	NOUN
biomedich-730	109	9	are	be	AUX
biomedich-730	109	10	formed	form	VERB
biomedich-730	109	11	with	with	ADP
biomedich-730	109	12	tyr	tyr	PROPN
biomedich-730	109	13	residues	residue	NOUN
biomedich-730	109	14	,	,	PUNCT
biomedich-730	109	15	and	and	CCONJ
biomedich-730	109	16	hydrophobic	hydrophobic	NOUN
biomedich-730	109	17	interactions	interaction	NOUN
biomedich-730	109	18	occur	occur	VERB
biomedich-730	109	19	between	between	ADP
biomedich-730	109	20	the	the	DET
biomedich-730	109	21	ligand	ligand	ADJ
biomedich-730	109	22	and	and	CCONJ
biomedich-730	109	23	aromatic	aromatic	ADJ
biomedich-730	109	24	residues	residue	NOUN
biomedich-730	109	25	.	.	PUNCT
biomedich-730	110	1	the	the	DET
biomedich-730	110	2	interplay	interplay	NOUN
biomedich-730	110	3	of	of	ADP
biomedich-730	110	4	these	these	DET
biomedich-730	110	5	interactions	interaction	NOUN
biomedich-730	110	6	demonstrates	demonstrate	VERB
biomedich-730	110	7	how	how	SCONJ
biomedich-730	110	8	hydrogen	hydrogen	NOUN
biomedich-730	110	9	bonds	bond	NOUN
biomedich-730	110	10	,	,	PUNCT
biomedich-730	110	11	π	π	PROPN
biomedich-730	110	12	-	-	PUNCT
biomedich-730	110	13	π	π	NOUN
biomedich-730	110	14	interactions	interaction	NOUN
biomedich-730	110	15	,	,	PUNCT
biomedich-730	110	16	and	and	CCONJ
biomedich-730	110	17	hydrophobic	hydrophobic	NOUN
biomedich-730	110	18	interactions	interaction	NOUN
biomedich-730	110	19	influence	influence	VERB
biomedich-730	110	20	the	the	DET
biomedich-730	110	21	ligand	ligand	NOUN
biomedich-730	110	22	's	's	PART
biomedich-730	110	23	stability	stability	NOUN
biomedich-730	110	24	with	with	ADP
biomedich-730	110	25	respect	respect	NOUN
biomedich-730	110	26	to	to	ADP
biomedich-730	110	27	the	the	DET
biomedich-730	110	28	protein	protein	NOUN
biomedich-730	110	29	in	in	ADP
biomedich-730	110	30	each	each	DET
biomedich-730	110	31	figure	figure	NOUN
biomedich-730	110	32	(	(	PUNCT
biomedich-730	110	33	figure	figure	NOUN
biomedich-730	110	34	4	4	NUM
biomedich-730	110	35	.	.	PUNCT
biomedich-730	110	36	)	)	PUNCT
biomedich-730	110	37	.	.	PUNCT
biomedich-730	111	1	figure	figure	VERB
biomedich-730	111	2	4	4	NUM
biomedich-730	111	3	.	.	PUNCT
biomedich-730	112	1	the	the	DET
biomedich-730	112	2	ramachandran	ramachandran	PROPN
biomedich-730	112	3	procheck	procheck	PROPN
biomedich-730	112	4	determined	determine	VERB
biomedich-730	112	5	the	the	DET
biomedich-730	112	6	plot	plot	NOUN
biomedich-730	112	7	.	.	PUNCT
biomedich-730	113	1	red	red	PROPN
biomedich-730	113	2	represents	represent	VERB
biomedich-730	113	3	a	a	DET
biomedich-730	113	4	preferred	preferred	ADJ
biomedich-730	113	5	region	region	NOUN
biomedich-730	113	6	,	,	PUNCT
biomedich-730	113	7	yellow	yellow	ADJ
biomedich-730	113	8	indicates	indicate	VERB
biomedich-730	113	9	an	an	DET
biomedich-730	113	10	authorized	authorized	ADJ
biomedich-730	113	11	region	region	NOUN
biomedich-730	113	12	,	,	PUNCT
biomedich-730	113	13	bright	bright	ADJ
biomedich-730	113	14	yellow	yellow	NOUN
biomedich-730	113	15	suggests	suggest	VERB
biomedich-730	113	16	an	an	DET
biomedich-730	113	17	amino	amino	NOUN
biomedich-730	113	18	acid	acid	NOUN
biomedich-730	113	19	region	region	NOUN
biomedich-730	113	20	that	that	PRON
biomedich-730	113	21	is	be	AUX
biomedich-730	113	22	liberally	liberally	ADV
biomedich-730	113	23	allowed	allow	VERB
biomedich-730	113	24	,	,	PUNCT
biomedich-730	113	25	and	and	CCONJ
biomedich-730	113	26	white	white	ADJ
biomedich-730	113	27	indicates	indicate	VERB
biomedich-730	113	28	a	a	DET
biomedich-730	113	29	banned	ban	VERB
biomedich-730	113	30	region	region	NOUN
biomedich-730	113	31	.	.	PUNCT
biomedich-730	114	1	in	in	ADP
biomedich-730	114	2	silico	silico	NOUN
biomedich-730	114	3	drug	drug	NOUN
biomedich-730	114	4	-	-	PUNCT
biomedich-730	114	5	likeness	likeness	NOUN
biomedich-730	114	6	and	and	CCONJ
biomedich-730	114	7	toxicity	toxicity	NOUN
biomedich-730	114	8	predictions	prediction	NOUN
biomedich-730	114	9	subsequent	subsequent	ADJ
biomedich-730	114	10	to	to	ADP
biomedich-730	114	11	molecular	molecular	ADJ
biomedich-730	114	12	docking	docking	NOUN
biomedich-730	114	13	analyses	analysis	NOUN
biomedich-730	114	14	,	,	PUNCT
biomedich-730	114	15	the	the	DET
biomedich-730	114	16	absorption	absorption	NOUN
biomedich-730	114	17	,	,	PUNCT
biomedich-730	114	18	distribution	distribution	NOUN
biomedich-730	114	19	,	,	PUNCT
biomedich-730	114	20	metabolism	metabolism	NOUN
biomedich-730	114	21	,	,	PUNCT
biomedich-730	114	22	elimination	elimination	NOUN
biomedich-730	114	23	,	,	PUNCT
biomedich-730	114	24	and	and	CCONJ
biomedich-730	114	25	toxicity	toxicity	NOUN
biomedich-730	114	26	(	(	PUNCT
biomedich-730	114	27	admet	admet	PROPN
biomedich-730	114	28	)	)	PUNCT
biomedich-730	114	29	of	of	ADP
biomedich-730	114	30	flavonoids	flavonoid	NOUN
biomedich-730	114	31	natural	natural	ADJ
biomedich-730	114	32	compound	compound	NOUN
biomedich-730	114	33	ligands	ligand	NOUN
biomedich-730	114	34	were	be	AUX
biomedich-730	114	35	evaluated	evaluate	VERB
biomedich-730	114	36	using	use	VERB
biomedich-730	114	37	the	the	DET
biomedich-730	114	38	swissadme	swissadme	NOUN
biomedich-730	114	39	(	(	PUNCT
biomedich-730	114	40	http://www.swissadme.ch/	http://www.swissadme.ch/	X
biomedich-730	114	41	)	)	PUNCT
biomedich-730	114	42	and	and	CCONJ
biomedich-730	114	43	protox-3.0	protox-3.0	ADV
biomedich-730	114	44	(	(	PUNCT
biomedich-730	114	45	https://tox.charite.de/protox3/	https://tox.charite.de/protox3/	PROPN
biomedich-730	114	46	)	)	PUNCT
biomedich-730	114	47	platforms	platform	NOUN
biomedich-730	114	48	to	to	PART
biomedich-730	114	49	forecast	forecast	VERB
biomedich-730	114	50	their	their	PRON
biomedich-730	114	51	significant	significant	ADJ
biomedich-730	114	52	pharmacokinetic	pharmacokinetic	ADJ
biomedich-730	114	53	characteristics	characteristic	NOUN
biomedich-730	114	54	.	.	PUNCT
biomedich-730	115	1	admet	admet	PROPN
biomedich-730	115	2	properties	property	NOUN
biomedich-730	115	3	encompass	encompass	VERB
biomedich-730	115	4	absorption	absorption	NOUN
biomedich-730	115	5	metrics	metric	NOUN
biomedich-730	115	6	such	such	ADJ
biomedich-730	115	7	as	as	ADP
biomedich-730	115	8	caco-2	caco-2	NUM
biomedich-730	115	9	permeability	permeability	NOUN
biomedich-730	115	10	,	,	PUNCT
biomedich-730	115	11	aqueous	aqueous	ADJ
biomedich-730	115	12	solubility	solubility	NOUN
biomedich-730	115	13	,	,	PUNCT
biomedich-730	115	14	human	human	ADJ
biomedich-730	115	15	intestinal	intestinal	ADJ
biomedich-730	115	16	absorption	absorption	NOUN
biomedich-730	115	17	,	,	PUNCT
biomedich-730	115	18	p	p	NOUN
biomedich-730	115	19	-	-	PUNCT
biomedich-730	115	20	glycoprotein	glycoprotein	NOUN
biomedich-730	115	21	substrates	substrate	NOUN
biomedich-730	115	22	,	,	PUNCT
biomedich-730	115	23	pglycoprotein	pglycoprotein	ADJ
biomedich-730	115	24	inhibitors	inhibitor	NOUN
biomedich-730	115	25	i	i	PRON
biomedich-730	115	26	and	and	CCONJ
biomedich-730	115	27	ii	ii	NOUN
biomedich-730	115	28	,	,	PUNCT
biomedich-730	115	29	and	and	CCONJ
biomedich-730	115	30	dermal	dermal	ADJ
biomedich-730	115	31	permeability	permeability	NOUN
biomedich-730	115	32	;	;	PUNCT
biomedich-730	115	33	distribution	distribution	NOUN
biomedich-730	115	34	factors	factor	NOUN
biomedich-730	115	35	including	include	VERB
biomedich-730	115	36	volume	volume	NOUN
biomedich-730	115	37	of	of	ADP
biomedich-730	115	38	steady	steady	ADJ
biomedich-730	115	39	-	-	PUNCT
biomedich-730	115	40	state	state	NOUN
biomedich-730	115	41	distribution	distribution	NOUN
biomedich-730	115	42	(	(	PUNCT
biomedich-730	115	43	vdss	vdss	ADJ
biomedich-730	115	44	)	)	PUNCT
biomedich-730	115	45	,	,	PUNCT
biomedich-730	115	46	unbound	unbound	NOUN
biomedich-730	115	47	fraction	fraction	NOUN
biomedich-730	115	48	,	,	PUNCT
biomedich-730	115	49	blood	blood	NOUN
biomedich-730	115	50	-	-	PUNCT
biomedich-730	115	51	brain	brain	NOUN
biomedich-730	115	52	barrier	barrier	NOUN
biomedich-730	115	53	(	(	PUNCT
biomedich-730	115	54	bbb	bbb	NOUN
biomedich-730	115	55	)	)	PUNCT
biomedich-730	115	56	permeability	permeability	NOUN
biomedich-730	115	57	,	,	PUNCT
biomedich-730	115	58	and	and	CCONJ
biomedich-730	115	59	central	central	ADJ
biomedich-730	115	60	nervous	nervous	ADJ
biomedich-730	115	61	system	system	NOUN
biomedich-730	115	62	(	(	PUNCT
biomedich-730	115	63	cns	cns	NOUN
biomedich-730	115	64	)	)	PUNCT
biomedich-730	115	65	permeability	permeability	NOUN
biomedich-730	115	66	;	;	PUNCT
biomedich-730	115	67	metabolic	metabolic	NOUN
biomedich-730	115	68	considerations	consideration	NOUN
biomedich-730	115	69	like	like	ADP
biomedich-730	115	70	cytochrome	cytochrome	NOUN
biomedich-730	115	71	p450	p450	NUM
biomedich-730	115	72	inhibition	inhibition	NOUN
biomedich-730	115	73	and	and	CCONJ
biomedich-730	115	74	cyp2d6	cyp2d6	NOUN
biomedich-730	115	75	/	/	SYM
biomedich-730	115	76	cyp3a4	cyp3a4	NOUN
biomedich-730	115	77	substrate	substrate	NOUN
biomedich-730	115	78	status	status	NOUN
biomedich-730	115	79	;	;	PUNCT
biomedich-730	115	80	excretion	excretion	NOUN
biomedich-730	115	81	parameters	parameter	NOUN
biomedich-730	115	82	such	such	ADJ
biomedich-730	115	83	as	as	ADP
biomedich-730	115	84	renal	renal	ADJ
biomedich-730	115	85	oct2	oct2	NOUN
biomedich-730	115	86	substrate	substrate	NOUN
biomedich-730	115	87	and	and	CCONJ
biomedich-730	115	88	total	total	ADJ
biomedich-730	115	89	drug	drug	NOUN
biomedich-730	115	90	clearance	clearance	NOUN
biomedich-730	115	91	;	;	PUNCT
biomedich-730	115	92	and	and	CCONJ
biomedich-730	115	93	toxicity	toxicity	NOUN
biomedich-730	115	94	assessments	assessment	NOUN
biomedich-730	115	95	including	include	VERB
biomedich-730	115	96	rat	rat	NOUN
biomedich-730	115	97	ld50	ld50	PROPN
biomedich-730	115	98	,	,	PUNCT
biomedich-730	115	99	ames	ames	PROPN
biomedich-730	115	100	test	test	NOUN
biomedich-730	115	101	results	result	NOUN
biomedich-730	115	102	,	,	PUNCT
biomedich-730	115	103	t.	t.	NOUN
biomedich-730	115	104	pyriformis	pyriformis	NOUN
biomedich-730	115	105	toxicity	toxicity	NOUN
biomedich-730	115	106	,	,	PUNCT
biomedich-730	115	107	small	small	ADJ
biomedich-730	115	108	fish	fish	NOUN
biomedich-730	115	109	toxicity	toxicity	NOUN
biomedich-730	115	110	,	,	PUNCT
biomedich-730	115	111	maximum	maximum	ADJ
biomedich-730	115	112	tolerated	tolerate	VERB
biomedich-730	115	113	dose	dose	NOUN
biomedich-730	115	114	,	,	PUNCT
biomedich-730	115	115	chronic	chronic	ADJ
biomedich-730	115	116	oral	oral	ADJ
biomedich-730	115	117	toxicity	toxicity	NOUN
biomedich-730	115	118	in	in	ADP
biomedich-730	115	119	rats	rat	NOUN
biomedich-730	115	120	,	,	PUNCT
biomedich-730	115	121	hepatotoxicity	hepatotoxicity	NOUN
biomedich-730	115	122	,	,	PUNCT
biomedich-730	115	123	skin	skin	NOUN
biomedich-730	115	124	sensitization	sensitization	NOUN
biomedich-730	115	125	,	,	PUNCT
biomedich-730	115	126	and	and	CCONJ
biomedich-730	115	127	herg	herg	PROPN
biomedich-730	115	128	inhibitors	inhibitor	NOUN
biomedich-730	115	129	i	i	PRON
biomedich-730	115	130	and	and	CCONJ
biomedich-730	115	131	ii	ii	PROPN
biomedich-730	115	132	.	.	PROPN
biomedich-730	115	133	drug	drug	PROPN
biomedich-730	115	134	similarity	similarity	NOUN
biomedich-730	115	135	characteristics	characteristic	NOUN
biomedich-730	115	136	were	be	AUX
biomedich-730	115	137	forecasted	forecast	VERB
biomedich-730	115	138	by	by	ADP
biomedich-730	115	139	submitting	submit	VERB
biomedich-730	115	140	the	the	DET
biomedich-730	115	141	structures	structure	NOUN
biomedich-730	115	142	of	of	ADP
biomedich-730	115	143	chosen	choose	VERB
biomedich-730	115	144	phytochemicals	phytochemical	NOUN
biomedich-730	115	145	in	in	ADP
biomedich-730	115	146	smiles	smile	NOUN
biomedich-730	115	147	format	format	NOUN
biomedich-730	115	148	(	(	PUNCT
biomedich-730	115	149	vardhan	vardhan	PROPN
biomedich-730	115	150	et	et	PROPN
biomedich-730	115	151	al	al	PROPN
biomedich-730	115	152	.	.	PROPN
biomedich-730	115	153	,	,	PUNCT
biomedich-730	115	154	2020	2020	NUM
biomedich-730	115	155	)	)	PUNCT
biomedich-730	115	156	.	.	PUNCT
biomedich-730	116	1	the	the	DET
biomedich-730	116	2	adme	adme	NOUN
biomedich-730	116	3	analysis	analysis	NOUN
biomedich-730	116	4	(	(	PUNCT
biomedich-730	116	5	figure	figure	NOUN
biomedich-730	116	6	5	5	NUM
biomedich-730	116	7	.	.	PUNCT
biomedich-730	116	8	)	)	PUNCT
biomedich-730	117	1	findings	finding	NOUN
biomedich-730	117	2	for	for	ADP
biomedich-730	117	3	the	the	DET
biomedich-730	117	4	compound	compound	NOUN
biomedich-730	117	5	,	,	PUNCT
biomedich-730	117	6	which	which	PRON
biomedich-730	117	7	has	have	VERB
biomedich-730	117	8	a	a	DET
biomedich-730	117	9	molecular	molecular	ADJ
biomedich-730	117	10	formula	formula	NOUN
biomedich-730	117	11	of	of	ADP
biomedich-730	117	12	c15h10o5	c15h10o5	PROPN
biomedich-730	117	13	and	and	CCONJ
biomedich-730	117	14	a	a	DET
biomedich-730	117	15	molecular	molecular	ADJ
biomedich-730	117	16	weight	weight	NOUN
biomedich-730	117	17	of	of	ADP
biomedich-730	117	18	270.24	270.24	NUM
biomedich-730	117	19	g	g	NOUN
biomedich-730	117	20	/	/	SYM
biomedich-730	117	21	mol	mol	NOUN
biomedich-730	117	22	,	,	PUNCT
biomedich-730	117	23	indicate	indicate	VERB
biomedich-730	117	24	that	that	SCONJ
biomedich-730	117	25	its	its	PRON
biomedich-730	117	26	physicochemical	physicochemical	ADJ
biomedich-730	117	27	properties	property	NOUN
biomedich-730	117	28	make	make	VERB
biomedich-730	117	29	it	it	PRON
biomedich-730	117	30	suitable	suitable	ADJ
biomedich-730	117	31	for	for	ADP
biomedich-730	117	32	further	further	ADJ
biomedich-730	117	33	development	development	NOUN
biomedich-730	117	34	as	as	ADP
biomedich-730	117	35	a	a	DET
biomedich-730	117	36	drug	drug	NOUN
biomedich-730	117	37	candidate	candidate	NOUN
biomedich-730	117	38	.	.	PUNCT
biomedich-730	118	1	the	the	DET
biomedich-730	118	2	heavy	heavy	ADJ
biomedich-730	118	3	atom	atom	NOUN
biomedich-730	118	4	count	count	NOUN
biomedich-730	118	5	of	of	ADP
biomedich-730	118	6	20	20	NUM
biomedich-730	118	7	and	and	CCONJ
biomedich-730	118	8	tpsa	tpsa	NOUN
biomedich-730	118	9	of	of	ADP
biomedich-730	118	10	90.90	90.90	NUM
biomedich-730	118	11	å²	å²	PROPN
biomedich-730	118	12	show	show	VERB
biomedich-730	118	13	that	that	SCONJ
biomedich-730	118	14	the	the	DET
biomedich-730	118	15	molecular	molecular	ADJ
biomedich-730	118	16	structure	structure	NOUN
biomedich-730	118	17	is	be	AUX
biomedich-730	118	18	stable	stable	ADJ
biomedich-730	118	19	and	and	CCONJ
biomedich-730	118	20	has	have	VERB
biomedich-730	118	21	good	good	ADJ
biomedich-730	118	22	membrane	membrane	NOUN
biomedich-730	118	23	penetration	penetration	NOUN
biomedich-730	118	24	ability	ability	NOUN
biomedich-730	118	25	.	.	PUNCT
biomedich-730	119	1	the	the	DET
biomedich-730	119	2	compound	compound	NOUN
biomedich-730	119	3	's	's	PART
biomedich-730	119	4	logp	logp	NOUN
biomedich-730	119	5	falls	fall	VERB
biomedich-730	119	6	between	between	ADP
biomedich-730	119	7	2.08	2.08	NUM
biomedich-730	119	8	and	and	CCONJ
biomedich-730	119	9	2.58	2.58	NUM
biomedich-730	119	10	,	,	PUNCT
biomedich-730	119	11	indicating	indicate	VERB
biomedich-730	119	12	an	an	DET
biomedich-730	119	13	equilibrium	equilibrium	NOUN
biomedich-730	119	14	between	between	ADP
biomedich-730	119	15	water	water	NOUN
biomedich-730	119	16	and	and	CCONJ
biomedich-730	119	17	lipid	lipid	NOUN
biomedich-730	119	18	solubility	solubility	NOUN
biomedich-730	119	19	that	that	PRON
biomedich-730	119	20	is	be	AUX
biomedich-730	119	21	crucial	crucial	ADJ
biomedich-730	119	22	for	for	ADP
biomedich-730	119	23	pharmacokinetics	pharmacokinetic	NOUN
biomedich-730	119	24	.	.	PUNCT
biomedich-730	120	1	the	the	DET
biomedich-730	120	2	compound	compound	NOUN
biomedich-730	120	3	has	have	VERB
biomedich-730	120	4	moderate	moderate	ADJ
biomedich-730	120	5	solubility	solubility	NOUN
biomedich-730	120	6	in	in	ADP
biomedich-730	120	7	water	water	NOUN
biomedich-730	120	8	based	base	VERB
biomedich-730	120	9	on	on	ADP
biomedich-730	120	10	different	different	ADJ
biomedich-730	120	11	techniques	technique	NOUN
biomedich-730	120	12	,	,	PUNCT
biomedich-730	120	13	such	such	ADJ
biomedich-730	120	14	as	as	ADP
biomedich-730	120	15	log	log	PROPN
biomedich-730	120	16	s	s	NOUN
biomedich-730	120	17	esol	esol	NOUN
biomedich-730	120	18	:	:	PUNCT
biomedich-730	120	19	-3.46	-3.46	X
biomedich-730	120	20	.	.	PUNCT
biomedich-730	121	1	regarding	regard	VERB
biomedich-730	121	2	pharmacokinetics	pharmacokinetic	NOUN
biomedich-730	121	3	,	,	PUNCT
biomedich-730	121	4	the	the	DET
biomedich-730	121	5	substance	substance	NOUN
biomedich-730	121	6	is	be	AUX
biomedich-730	121	7	easily	easily	ADV
biomedich-730	121	8	absorbed	absorb	VERB
biomedich-730	121	9	in	in	ADP
biomedich-730	121	10	the	the	DET
biomedich-730	121	11	gastrointestinal	gastrointestinal	ADJ
biomedich-730	121	12	tract	tract	NOUN
biomedich-730	121	13	,	,	PUNCT
biomedich-730	121	14	yet	yet	ADV
biomedich-730	121	15	can	can	AUX
biomedich-730	121	16	not	not	PART
biomedich-730	121	17	pass	pass	VERB
biomedich-730	121	18	through	through	ADP
biomedich-730	121	19	the	the	DET
biomedich-730	121	20	blood	blood	NOUN
biomedich-730	121	21	-	-	PUNCT
biomedich-730	121	22	brain	brain	NOUN
biomedich-730	121	23	barrier	barrier	NOUN
biomedich-730	121	24	,	,	PUNCT
biomedich-730	121	25	therefore	therefore	ADV
biomedich-730	121	26	the	the	DET
biomedich-730	121	27	chances	chance	NOUN
biomedich-730	121	28	of	of	ADP
biomedich-730	121	29	negative	negative	ADJ
biomedich-730	121	30	impacts	impact	NOUN
biomedich-730	121	31	on	on	ADP
biomedich-730	121	32	the	the	DET
biomedich-730	121	33	central	central	ADJ
biomedich-730	121	34	nervous	nervous	ADJ
biomedich-730	121	35	system	system	NOUN
biomedich-730	121	36	are	be	AUX
biomedich-730	121	37	expected	expect	VERB
biomedich-730	121	38	to	to	PART
biomedich-730	121	39	be	be	AUX
biomedich-730	121	40	minimal	minimal	ADJ
biomedich-730	121	41	.	.	PUNCT
biomedich-730	122	1	nevertheless	nevertheless	ADV
biomedich-730	122	2	,	,	PUNCT
biomedich-730	122	3	the	the	DET
biomedich-730	122	4	compound	compound	NOUN
biomedich-730	122	5	may	may	AUX
biomedich-730	122	6	block	block	VERB
biomedich-730	122	7	cyp1a2	cyp1a2	PROPN
biomedich-730	122	8	,	,	PUNCT
biomedich-730	122	9	cyp2d6	cyp2d6	NOUN
biomedich-730	122	10	,	,	PUNCT
biomedich-730	122	11	and	and	CCONJ
biomedich-730	122	12	cyp3a4	cyp3a4	PROPN
biomedich-730	122	13	enzymes	enzyme	NOUN
biomedich-730	122	14	,	,	PUNCT
biomedich-730	122	15	thus	thus	ADV
biomedich-730	122	16	requiring	require	VERB
biomedich-730	122	17	increased	increase	VERB
biomedich-730	122	18	focus	focus	NOUN
biomedich-730	122	19	on	on	ADP
biomedich-730	122	20	potential	potential	ADJ
biomedich-730	122	21	interactions	interaction	NOUN
biomedich-730	122	22	with	with	ADP
biomedich-730	122	23	other	other	ADJ
biomedich-730	122	24	medications	medication	NOUN
biomedich-730	122	25	processed	process	VERB
biomedich-730	122	26	through	through	ADP
biomedich-730	122	27	this	this	DET
biomedich-730	122	28	pathway	pathway	NOUN
biomedich-730	122	29	.	.	PUNCT
biomedich-730	123	1	the	the	DET
biomedich-730	123	2	skin	skin	NOUN
biomedich-730	123	3	permeability	permeability	NOUN
biomedich-730	123	4	is	be	AUX
biomedich-730	123	5	poor	poor	ADJ
biomedich-730	123	6	,	,	PUNCT
biomedich-730	123	7	indicated	indicate	VERB
biomedich-730	123	8	by	by	ADP
biomedich-730	123	9	a	a	DET
biomedich-730	123	10	log	log	NOUN
biomedich-730	123	11	kp	kp	PROPN
biomedich-730	123	12	value	value	NOUN
biomedich-730	123	13	of	of	ADP
biomedich-730	123	14	-6.35	-6.35	ADJ
biomedich-730	123	15	cm	cm	NOUN
biomedich-730	123	16	/	/	SYM
biomedich-730	123	17	s.	s.	PROPN
biomedich-730	123	18	280	280	NUM
biomedich-730	123	19	biology	biology	NOUN
biomedich-730	123	20	,	,	PUNCT
biomedich-730	123	21	medicine	medicine	NOUN
biomedich-730	123	22	,	,	PUNCT
biomedich-730	123	23	&	&	CCONJ
biomedich-730	123	24	natural	natural	ADJ
biomedich-730	123	25	product	product	NOUN
biomedich-730	123	26	chemistry	chemistry	NOUN
biomedich-730	123	27	14	14	NUM
biomedich-730	123	28	(	(	PUNCT
biomedich-730	123	29	1	1	NUM
biomedich-730	123	30	)	)	PUNCT
biomedich-730	123	31	,	,	PUNCT
biomedich-730	123	32	2025	2025	NUM
biomedich-730	123	33	:	:	PUNCT
biomedich-730	123	34	275	275	NUM
biomedich-730	123	35	-	-	SYM
biomedich-730	123	36	282	282	NUM
biomedich-730	123	37	assessment	assessment	NOUN
biomedich-730	123	38	of	of	ADP
biomedich-730	123	39	drug	drug	NOUN
biomedich-730	123	40	likeness	likeness	NOUN
biomedich-730	123	41	indicated	indicate	VERB
biomedich-730	123	42	that	that	SCONJ
biomedich-730	123	43	this	this	DET
biomedich-730	123	44	compound	compound	NOUN
biomedich-730	123	45	adhered	adhere	VERB
biomedich-730	123	46	to	to	ADP
biomedich-730	123	47	key	key	ADJ
biomedich-730	123	48	guidelines	guideline	NOUN
biomedich-730	123	49	such	such	ADJ
biomedich-730	123	50	as	as	ADP
biomedich-730	123	51	lipinski	lipinski	PROPN
biomedich-730	123	52	,	,	PUNCT
biomedich-730	123	53	ghose	ghose	PROPN
biomedich-730	123	54	,	,	PUNCT
biomedich-730	123	55	veber	veber	PROPN
biomedich-730	123	56	,	,	PUNCT
biomedich-730	123	57	egan	egan	PROPN
biomedich-730	123	58	,	,	PUNCT
biomedich-730	123	59	and	and	CCONJ
biomedich-730	123	60	muegge	muegge	ADV
biomedich-730	123	61	without	without	ADP
biomedich-730	123	62	any	any	DET
biomedich-730	123	63	breaches	breach	NOUN
biomedich-730	123	64	,	,	PUNCT
biomedich-730	123	65	with	with	ADP
biomedich-730	123	66	a	a	DET
biomedich-730	123	67	bioavailability	bioavailability	NOUN
biomedich-730	123	68	score	score	NOUN
biomedich-730	123	69	of	of	ADP
biomedich-730	123	70	0.55	0.55	NUM
biomedich-730	123	71	.	.	PUNCT
biomedich-730	124	1	in	in	ADP
biomedich-730	124	2	terms	term	NOUN
biomedich-730	124	3	of	of	ADP
biomedich-730	124	4	medicinal	medicinal	ADJ
biomedich-730	124	5	chemistry	chemistry	NOUN
biomedich-730	124	6	,	,	PUNCT
biomedich-730	124	7	this	this	DET
biomedich-730	124	8	compound	compound	NOUN
biomedich-730	124	9	exhibits	exhibit	VERB
biomedich-730	124	10	no	no	DET
biomedich-730	124	11	pains	pain	NOUN
biomedich-730	124	12	alerts	alert	NOUN
biomedich-730	124	13	or	or	CCONJ
biomedich-730	124	14	lead	lead	VERB
biomedich-730	124	15	likeness	likeness	NOUN
biomedich-730	124	16	,	,	PUNCT
biomedich-730	124	17	indicating	indicate	VERB
biomedich-730	124	18	high	high	ADJ
biomedich-730	124	19	promise	promise	NOUN
biomedich-730	124	20	as	as	ADP
biomedich-730	124	21	a	a	DET
biomedich-730	124	22	potential	potential	ADJ
biomedich-730	124	23	lead	lead	NOUN
biomedich-730	124	24	in	in	ADP
biomedich-730	124	25	drug	drug	NOUN
biomedich-730	124	26	development	development	NOUN
biomedich-730	124	27	with	with	ADP
biomedich-730	124	28	minimal	minimal	ADJ
biomedich-730	124	29	risk	risk	NOUN
biomedich-730	124	30	of	of	ADP
biomedich-730	124	31	false	false	ADJ
biomedich-730	124	32	positives	positive	NOUN
biomedich-730	124	33	in	in	ADP
biomedich-730	124	34	biological	biological	ADJ
biomedich-730	124	35	assays	assay	NOUN
biomedich-730	124	36	.	.	PUNCT
biomedich-730	125	1	the	the	DET
biomedich-730	125	2	compound	compound	NOUN
biomedich-730	125	3	's	's	PART
biomedich-730	125	4	polarity	polarity	NOUN
biomedich-730	125	5	profile	profile	NOUN
biomedich-730	125	6	,	,	PUNCT
biomedich-730	125	7	lipophilicity	lipophilicity	NOUN
biomedich-730	125	8	,	,	PUNCT
biomedich-730	125	9	and	and	CCONJ
biomedich-730	125	10	flexibility	flexibility	NOUN
biomedich-730	125	11	are	be	AUX
biomedich-730	125	12	within	within	ADP
biomedich-730	125	13	accepted	accept	VERB
biomedich-730	125	14	ranges	range	NOUN
biomedich-730	125	15	for	for	ADP
biomedich-730	125	16	promoting	promote	VERB
biomedich-730	125	17	biological	biological	ADJ
biomedich-730	125	18	activity	activity	NOUN
biomedich-730	125	19	.	.	PUNCT
biomedich-730	126	1	in	in	ADP
biomedich-730	126	2	general	general	ADJ
biomedich-730	126	3	,	,	PUNCT
biomedich-730	126	4	the	the	DET
biomedich-730	126	5	compound	compound	NOUN
biomedich-730	126	6	deserves	deserve	VERB
biomedich-730	126	7	more	more	ADJ
biomedich-730	126	8	research	research	NOUN
biomedich-730	126	9	with	with	ADP
biomedich-730	126	10	a	a	DET
biomedich-730	126	11	focus	focus	NOUN
biomedich-730	126	12	on	on	ADP
biomedich-730	126	13	its	its	PRON
biomedich-730	126	14	metabolic	metabolic	NOUN
biomedich-730	126	15	interactions	interaction	NOUN
biomedich-730	126	16	.	.	PUNCT
biomedich-730	127	1	the	the	DET
biomedich-730	127	2	study	study	NOUN
biomedich-730	127	3	's	's	PART
biomedich-730	127	4	analysis	analysis	NOUN
biomedich-730	127	5	of	of	ADP
biomedich-730	127	6	toxicity	toxicity	NOUN
biomedich-730	127	7	resulted	result	VERB
biomedich-730	127	8	in	in	ADP
biomedich-730	127	9	an	an	DET
biomedich-730	127	10	ld50	ld50	PROPN
biomedich-730	127	11	value	value	NOUN
biomedich-730	127	12	of	of	ADP
biomedich-730	127	13	3919	3919	NUM
biomedich-730	127	14	mg	mg	PROPN
biomedich-730	127	15	/	/	SYM
biomedich-730	127	16	kg	kg	PROPN
biomedich-730	127	17	(	(	PUNCT
biomedich-730	127	18	figure	figure	NOUN
biomedich-730	127	19	5	5	NUM
biomedich-730	127	20	.	.	PUNCT
biomedich-730	127	21	)	)	PUNCT
biomedich-730	127	22	.	.	PUNCT
biomedich-730	128	1	this	this	DET
biomedich-730	128	2	value	value	NOUN
biomedich-730	128	3	shows	show	VERB
biomedich-730	128	4	that	that	SCONJ
biomedich-730	128	5	the	the	DET
biomedich-730	128	6	oral	oral	ADJ
biomedich-730	128	7	dose	dose	NOUN
biomedich-730	128	8	is	be	AUX
biomedich-730	128	9	lethal	lethal	ADJ
biomedich-730	128	10	for	for	ADP
biomedich-730	128	11	half	half	NOUN
biomedich-730	128	12	of	of	ADP
biomedich-730	128	13	the	the	DET
biomedich-730	128	14	test	test	NOUN
biomedich-730	128	15	animal	animal	NOUN
biomedich-730	128	16	population	population	NOUN
biomedich-730	128	17	.	.	PUNCT
biomedich-730	129	1	the	the	DET
biomedich-730	129	2	low	low	ADJ
biomedich-730	129	3	toxicity	toxicity	NOUN
biomedich-730	129	4	classification	classification	NOUN
biomedich-730	129	5	is	be	AUX
biomedich-730	129	6	based	base	VERB
biomedich-730	129	7	on	on	ADP
biomedich-730	129	8	the	the	DET
biomedich-730	129	9	relationship	relationship	NOUN
biomedich-730	129	10	between	between	ADP
biomedich-730	129	11	the	the	DET
biomedich-730	129	12	ld50	ld50	PROPN
biomedich-730	129	13	value	value	NOUN
biomedich-730	129	14	and	and	CCONJ
biomedich-730	129	15	the	the	DET
biomedich-730	129	16	level	level	NOUN
biomedich-730	129	17	of	of	ADP
biomedich-730	129	18	toxicity	toxicity	NOUN
biomedich-730	129	19	risk	risk	NOUN
biomedich-730	129	20	.	.	PUNCT
biomedich-730	130	1	the	the	DET
biomedich-730	130	2	findings	finding	NOUN
biomedich-730	130	3	of	of	ADP
biomedich-730	130	4	this	this	DET
biomedich-730	130	5	study	study	NOUN
biomedich-730	130	6	indicated	indicate	VERB
biomedich-730	130	7	a	a	DET
biomedich-730	130	8	toxicity	toxicity	NOUN
biomedich-730	130	9	class	class	NOUN
biomedich-730	130	10	of	of	ADP
biomedich-730	130	11	5	5	NUM
biomedich-730	130	12	.	.	PUNCT
biomedich-730	130	13	based	base	VERB
biomedich-730	130	14	on	on	ADP
biomedich-730	130	15	this	this	DET
biomedich-730	130	16	categorization	categorization	NOUN
biomedich-730	130	17	of	of	ADP
biomedich-730	130	18	toxicity	toxicity	NOUN
biomedich-730	130	19	,	,	PUNCT
biomedich-730	130	20	substances	substance	NOUN
biomedich-730	130	21	in	in	ADP
biomedich-730	130	22	class	class	NOUN
biomedich-730	130	23	5	5	NUM
biomedich-730	130	24	have	have	VERB
biomedich-730	130	25	very	very	ADV
biomedich-730	130	26	low	low	ADJ
biomedich-730	130	27	toxicity	toxicity	NOUN
biomedich-730	130	28	and	and	CCONJ
biomedich-730	130	29	present	present	ADJ
biomedich-730	130	30	little	little	ADJ
biomedich-730	130	31	danger	danger	NOUN
biomedich-730	130	32	when	when	SCONJ
biomedich-730	130	33	used	use	VERB
biomedich-730	130	34	as	as	ADP
biomedich-730	130	35	directed	direct	VERB
biomedich-730	130	36	.	.	PUNCT
biomedich-730	131	1	figure	figure	NOUN
biomedich-730	131	2	5	5	NUM
biomedich-730	131	3	.	.	PUNCT
biomedich-730	132	1	admet	admet	PROPN
biomedich-730	132	2	analysis	analysis	NOUN
biomedich-730	132	3	of	of	ADP
biomedich-730	132	4	flavonoid	flavonoid	NOUN
biomedich-730	132	5	drugs	drug	NOUN
biomedich-730	132	6	demonstrating	demonstrate	VERB
biomedich-730	132	7	profiles	profile	NOUN
biomedich-730	132	8	of	of	ADP
biomedich-730	132	9	absorption	absorption	NOUN
biomedich-730	132	10	,	,	PUNCT
biomedich-730	132	11	distribution	distribution	NOUN
biomedich-730	132	12	,	,	PUNCT
biomedich-730	132	13	metabolism	metabolism	NOUN
biomedich-730	132	14	,	,	PUNCT
biomedich-730	132	15	excretion	excretion	NOUN
biomedich-730	132	16	,	,	PUNCT
biomedich-730	132	17	and	and	CCONJ
biomedich-730	132	18	toxicity	toxicity	NOUN
biomedich-730	132	19	.	.	PUNCT
biomedich-730	133	1	this	this	DET
biomedich-730	133	2	data	data	NOUN
biomedich-730	133	3	is	be	AUX
biomedich-730	133	4	utilized	utilize	VERB
biomedich-730	133	5	to	to	PART
biomedich-730	133	6	assess	assess	VERB
biomedich-730	133	7	the	the	DET
biomedich-730	133	8	pharmacokinetic	pharmacokinetic	ADJ
biomedich-730	133	9	potential	potential	NOUN
biomedich-730	133	10	and	and	CCONJ
biomedich-730	133	11	safety	safety	NOUN
biomedich-730	133	12	of	of	ADP
biomedich-730	133	13	substances	substance	NOUN
biomedich-730	133	14	in	in	ADP
biomedich-730	133	15	medication	medication	NOUN
biomedich-730	133	16	development	development	NOUN
biomedich-730	133	17	.	.	PUNCT
biomedich-730	134	1	conclusions	conclusion	NOUN
biomedich-730	134	2	this	this	DET
biomedich-730	134	3	study	study	NOUN
biomedich-730	134	4	highlights	highlight	VERB
biomedich-730	134	5	the	the	DET
biomedich-730	134	6	potential	potential	NOUN
biomedich-730	134	7	of	of	ADP
biomedich-730	134	8	flavonoids	flavonoid	NOUN
biomedich-730	134	9	as	as	ADP
biomedich-730	134	10	natural	natural	ADJ
biomedich-730	134	11	alternatives	alternative	NOUN
biomedich-730	134	12	for	for	ADP
biomedich-730	134	13	antihypertensive	antihypertensive	ADJ
biomedich-730	134	14	therapy	therapy	NOUN
biomedich-730	134	15	,	,	PUNCT
biomedich-730	134	16	focusing	focus	VERB
biomedich-730	134	17	on	on	ADP
biomedich-730	134	18	their	their	PRON
biomedich-730	134	19	interaction	interaction	NOUN
biomedich-730	134	20	with	with	ADP
biomedich-730	134	21	the	the	DET
biomedich-730	134	22	angiotensin	angiotensin	PROPN
biomedich-730	134	23	ii	ii	PROPN
biomedich-730	134	24	type1	type1	PROPN
biomedich-730	134	25	receptor	receptor	NOUN
biomedich-730	134	26	(	(	PUNCT
biomedich-730	134	27	at1r	at1r	NOUN
biomedich-730	134	28	)	)	PUNCT
biomedich-730	134	29	through	through	ADP
biomedich-730	134	30	in	in	ADP
biomedich-730	134	31	silico	silico	NOUN
biomedich-730	134	32	molecular	molecular	ADJ
biomedich-730	134	33	docking	docking	NOUN
biomedich-730	134	34	.	.	PUNCT
biomedich-730	135	1	the	the	DET
biomedich-730	135	2	findings	finding	NOUN
biomedich-730	135	3	suggest	suggest	VERB
biomedich-730	135	4	that	that	SCONJ
biomedich-730	135	5	flavonoids	flavonoid	NOUN
biomedich-730	135	6	,	,	PUNCT
biomedich-730	135	7	derived	derive	VERB
biomedich-730	135	8	from	from	ADP
biomedich-730	135	9	ocimum	ocimum	PROPN
biomedich-730	135	10	basilicum	basilicum	NOUN
biomedich-730	135	11	,	,	PUNCT
biomedich-730	135	12	exhibit	exhibit	VERB
biomedich-730	135	13	significant	significant	ADJ
biomedich-730	135	14	binding	bind	VERB
biomedich-730	135	15	affinity	affinity	NOUN
biomedich-730	135	16	to	to	ADP
biomedich-730	135	17	at1r	at1r	ADV
biomedich-730	135	18	,	,	PUNCT
biomedich-730	135	19	supporting	support	VERB
biomedich-730	135	20	their	their	PRON
biomedich-730	135	21	role	role	NOUN
biomedich-730	135	22	in	in	ADP
biomedich-730	135	23	reducing	reduce	VERB
biomedich-730	135	24	blood	blood	NOUN
biomedich-730	135	25	pressure	pressure	NOUN
biomedich-730	135	26	.	.	PUNCT
biomedich-730	136	1	structural	structural	ADJ
biomedich-730	136	2	validation	validation	NOUN
biomedich-730	136	3	of	of	ADP
biomedich-730	136	4	the	the	DET
biomedich-730	136	5	at1r	at1r	PROPN
biomedich-730	136	6	protein	protein	NOUN
biomedich-730	136	7	strengthens	strengthen	VERB
biomedich-730	136	8	the	the	DET
biomedich-730	136	9	reliability	reliability	NOUN
biomedich-730	136	10	of	of	ADP
biomedich-730	136	11	the	the	DET
biomedich-730	136	12	results	result	NOUN
biomedich-730	136	13	.	.	PUNCT
biomedich-730	137	1	this	this	DET
biomedich-730	137	2	study	study	NOUN
biomedich-730	137	3	provides	provide	VERB
biomedich-730	137	4	a	a	DET
biomedich-730	137	5	basis	basis	NOUN
biomedich-730	137	6	for	for	ADP
biomedich-730	137	7	developing	develop	VERB
biomedich-730	137	8	plant	plant	NOUN
biomedich-730	137	9	-	-	PUNCT
biomedich-730	137	10	based	base	VERB
biomedich-730	137	11	antihypertensive	antihypertensive	ADJ
biomedich-730	137	12	agents	agent	NOUN
biomedich-730	137	13	,	,	PUNCT
biomedich-730	137	14	encouraging	encourage	VERB
biomedich-730	137	15	further	further	ADJ
biomedich-730	137	16	experimental	experimental	ADJ
biomedich-730	137	17	studies	study	NOUN
biomedich-730	137	18	and	and	CCONJ
biomedich-730	137	19	clinical	clinical	ADJ
biomedich-730	137	20	trials	trial	NOUN
biomedich-730	137	21	to	to	PART
biomedich-730	137	22	confirm	confirm	VERB
biomedich-730	137	23	the	the	DET
biomedich-730	137	24	efficacy	efficacy	NOUN
biomedich-730	137	25	and	and	CCONJ
biomedich-730	137	26	safety	safety	NOUN
biomedich-730	137	27	of	of	ADP
biomedich-730	137	28	flavonoidsbased	flavonoidsbase	VERB
biomedich-730	137	29	therapies	therapy	NOUN
biomedich-730	137	30	.	.	PUNCT
biomedich-730	138	1	these	these	DET
biomedich-730	138	2	insights	insight	NOUN
biomedich-730	138	3	can	can	AUX
biomedich-730	138	4	contribute	contribute	VERB
biomedich-730	138	5	significantly	significantly	ADV
biomedich-730	138	6	to	to	ADP
biomedich-730	138	7	advancing	advance	VERB
biomedich-730	138	8	personalized	personalized	ADJ
biomedich-730	138	9	and	and	CCONJ
biomedich-730	138	10	sustainable	sustainable	ADJ
biomedich-730	138	11	healthcare	healthcare	NOUN
biomedich-730	138	12	solutions	solution	NOUN
biomedich-730	138	13	.	.	PUNCT
biomedich-730	139	1	acknowledgements	acknowledgement	NOUN
biomedich-730	139	2	:	:	PUNCT
biomedich-730	139	3	the	the	DET
biomedich-730	139	4	author	author	NOUN
biomedich-730	139	5	thanks	thank	NOUN
biomedich-730	139	6	to	to	ADP
biomedich-730	139	7	university	university	PROPN
biomedich-730	139	8	of	of	ADP
biomedich-730	139	9	muhammadiyah	muhammadiyah	NOUN
biomedich-730	139	10	purwokerto	purwokerto	NOUN
biomedich-730	139	11	for	for	ADP
biomedich-730	139	12	the	the	DET
biomedich-730	139	13	time	time	NOUN
biomedich-730	139	14	given	give	VERB
biomedich-730	139	15	to	to	PART
biomedich-730	139	16	conduct	conduct	VERB
biomedich-730	139	17	research	research	NOUN
biomedich-730	139	18	as	as	ADV
biomedich-730	139	19	well	well	ADV
biomedich-730	139	20	as	as	ADP
biomedich-730	139	21	the	the	DET
biomedich-730	139	22	provision	provision	NOUN
biomedich-730	139	23	of	of	ADP
biomedich-730	139	24	computers	computer	NOUN
biomedich-730	139	25	for	for	ADP
biomedich-730	139	26	docking	dock	VERB
biomedich-730	139	27	with	with	ADP
biomedich-730	139	28	the	the	DET
biomedich-730	139	29	required	require	VERB
biomedich-730	139	30	specifications	specification	NOUN
biomedich-730	139	31	.	.	PUNCT
biomedich-730	140	1	thalib	thalib	PROPN
biomedich-730	140	2	&	&	CCONJ
biomedich-730	140	3	damayanti	damayanti	PROPN
biomedich-730	140	4	–	–	PUNCT
biomedich-730	140	5	in	in	ADP
biomedich-730	140	6	silico	silico	NOUN
biomedich-730	140	7	analysis	analysis	NOUN
biomedich-730	140	8	of	of	ADP
biomedich-730	140	9	ocimum	ocimum	ADJ
biomedich-730	140	10	basilicum	basilicum	NOUN
biomedich-730	140	11	flavonoids	flavonoid	NOUN
biomedich-730	140	12	as	as	ADP
biomedich-730	140	13	…	…	PUNCT
biomedich-730	140	14	281	281	NUM
biomedich-730	140	15	authors	author	NOUN
biomedich-730	140	16	’	’	PART
biomedich-730	140	17	contributions	contribution	NOUN
biomedich-730	140	18	:	:	PUNCT
biomedich-730	140	19	irma	irma	PROPN
biomedich-730	140	20	putri	putri	PROPN
biomedich-730	140	21	damayanti	damayanti	PROPN
biomedich-730	140	22	designed	design	VERB
biomedich-730	140	23	the	the	DET
biomedich-730	140	24	study	study	NOUN
biomedich-730	140	25	,	,	PUNCT
biomedich-730	140	26	provided	provide	VERB
biomedich-730	140	27	input	input	NOUN
biomedich-730	140	28	and	and	CCONJ
biomedich-730	140	29	supervised	supervise	VERB
biomedich-730	140	30	the	the	DET
biomedich-730	140	31	docking	docking	NOUN
biomedich-730	140	32	.	.	PUNCT
biomedich-730	141	1	amir	amir	PROPN
biomedich-730	141	2	carried	carry	VERB
biomedich-730	141	3	out	out	ADP
biomedich-730	141	4	the	the	DET
biomedich-730	141	5	docking	docking	NOUN
biomedich-730	141	6	work	work	NOUN
biomedich-730	141	7	,	,	PUNCT
biomedich-730	141	8	analyzed	analyze	VERB
biomedich-730	141	9	the	the	DET
biomedich-730	141	10	data	datum	NOUN
biomedich-730	141	11	and	and	CCONJ
biomedich-730	141	12	wrote	write	VERB
biomedich-730	141	13	the	the	DET
biomedich-730	141	14	manuscript	manuscript	NOUN
biomedich-730	141	15	.	.	PUNCT
biomedich-730	142	1	all	all	DET
biomedich-730	142	2	authors	author	NOUN
biomedich-730	142	3	read	read	VERB
biomedich-730	142	4	and	and	CCONJ
biomedich-730	142	5	approved	approve	VERB
biomedich-730	142	6	the	the	DET
biomedich-730	142	7	final	final	ADJ
biomedich-730	142	8	version	version	NOUN
biomedich-730	142	9	of	of	ADP
biomedich-730	142	10	the	the	DET
biomedich-730	142	11	manuscript	manuscript	NOUN
biomedich-730	142	12	competing	compete	VERB
biomedich-730	142	13	interests	interest	NOUN
biomedich-730	142	14	:	:	PUNCT
biomedich-730	142	15	the	the	DET
biomedich-730	142	16	authors	author	NOUN
biomedich-730	142	17	declare	declare	VERB
biomedich-730	142	18	that	that	SCONJ
biomedich-730	142	19	there	there	PRON
biomedich-730	142	20	are	be	VERB
biomedich-730	142	21	no	no	DET
biomedich-730	142	22	competing	compete	VERB
biomedich-730	142	23	interests	interest	NOUN
biomedich-730	142	24	.	.	PUNCT
biomedich-730	143	1	funding	funding	NOUN
biomedich-730	143	2	:	:	PUNCT
biomedich-730	143	3	the	the	DET
biomedich-730	143	4	authors	author	NOUN
biomedich-730	143	5	declare	declare	VERB
biomedich-730	143	6	no	no	DET
biomedich-730	143	7	funding	funding	NOUN
biomedich-730	143	8	in	in	ADP
biomedich-730	143	9	this	this	DET
biomedich-730	143	10	research	research	NOUN
biomedich-730	143	11	.	.	PUNCT
biomedich-730	144	1	references	reference	NOUN
biomedich-730	144	2	agu	agu	NOUN
biomedich-730	144	3	,	,	PUNCT
biomedich-730	144	4	p.	p.	PROPN
biomedich-730	144	5	c.	c.	PROPN
biomedich-730	144	6	,	,	PUNCT
biomedich-730	144	7	afiukwa	afiukwa	PROPN
biomedich-730	144	8	,	,	PUNCT
biomedich-730	144	9	c.	c.	PROPN
biomedich-730	144	10	a.	a.	PROPN
biomedich-730	144	11	,	,	PUNCT
biomedich-730	144	12	orji	orji	PROPN
biomedich-730	144	13	,	,	PUNCT
biomedich-730	144	14	o.	o.	PROPN
biomedich-730	144	15	u.	u.	PROPN
biomedich-730	144	16	,	,	PUNCT
biomedich-730	144	17	ezeh	ezeh	PROPN
biomedich-730	144	18	,	,	PUNCT
biomedich-730	144	19	e.	e.	PROPN
biomedich-730	144	20	m.	m.	PROPN
biomedich-730	144	21	,	,	PUNCT
biomedich-730	144	22	ofoke	ofoke	PROPN
biomedich-730	144	23	,	,	PUNCT
biomedich-730	144	24	i.	i.	PROPN
biomedich-730	144	25	h.	h.	PROPN
biomedich-730	144	26	,	,	PUNCT
biomedich-730	144	27	ogbu	ogbu	ADV
biomedich-730	144	28	,	,	PUNCT
biomedich-730	144	29	c.	c.	PROPN
biomedich-730	144	30	o.	o.	PROPN
biomedich-730	144	31	,	,	PUNCT
biomedich-730	144	32	ugwuja	ugwuja	PROPN
biomedich-730	144	33	,	,	PUNCT
biomedich-730	144	34	e.	e.	PROPN
biomedich-730	144	35	i.	i.	PROPN
biomedich-730	144	36	,	,	PUNCT
biomedich-730	144	37	&	&	CCONJ
biomedich-730	144	38	aja	aja	PROPN
biomedich-730	144	39	,	,	PUNCT
biomedich-730	144	40	p.	p.	NOUN
biomedich-730	144	41	m.	m.	NOUN
biomedich-730	144	42	(	(	PUNCT
biomedich-730	144	43	2023	2023	NUM
biomedich-730	144	44	)	)	PUNCT
biomedich-730	144	45	.	.	PUNCT
biomedich-730	145	1	molecular	molecular	ADJ
biomedich-730	145	2	docking	docking	NOUN
biomedich-730	145	3	as	as	ADP
biomedich-730	145	4	a	a	DET
biomedich-730	145	5	tool	tool	NOUN
biomedich-730	145	6	for	for	ADP
biomedich-730	145	7	the	the	DET
biomedich-730	145	8	discovery	discovery	NOUN
biomedich-730	145	9	of	of	ADP
biomedich-730	145	10	molecular	molecular	ADJ
biomedich-730	145	11	targets	target	NOUN
biomedich-730	145	12	of	of	ADP
biomedich-730	145	13	nutraceuticals	nutraceutical	NOUN
biomedich-730	145	14	in	in	ADP
biomedich-730	145	15	diseases	disease	NOUN
biomedich-730	145	16	management	management	NOUN
biomedich-730	145	17	.	.	PUNCT
biomedich-730	146	1	scientific	scientific	ADJ
biomedich-730	146	2	reports	report	NOUN
biomedich-730	146	3	,	,	PUNCT
biomedich-730	146	4	13(1	13(1	NUM
biomedich-730	146	5	)	)	PUNCT
biomedich-730	146	6	,	,	PUNCT
biomedich-730	146	7	13398	13398	NUM
biomedich-730	146	8	.	.	PUNCT
biomedich-730	147	1	https://doi.org/10.1038/s41598-023-40160-2	https://doi.org/10.1038/s41598-023-40160-2	PROPN
biomedich-730	147	2	ali	ali	PROPN
biomedich-730	147	3	,	,	PUNCT
biomedich-730	147	4	s.	s.	PROPN
biomedich-730	147	5	,	,	PUNCT
biomedich-730	147	6	ali	ali	PROPN
biomedich-730	147	7	,	,	PUNCT
biomedich-730	147	8	u.	u.	PROPN
biomedich-730	147	9	,	,	PUNCT
biomedich-730	147	10	safi	safi	PROPN
biomedich-730	147	11	,	,	PUNCT
biomedich-730	147	12	k.	k.	PROPN
biomedich-730	147	13	,	,	PUNCT
biomedich-730	147	14	naz	naz	PROPN
biomedich-730	147	15	,	,	PUNCT
biomedich-730	147	16	f.	f.	PROPN
biomedich-730	147	17	,	,	PUNCT
biomedich-730	147	18	jan	jan	PROPN
biomedich-730	147	19	,	,	PUNCT
biomedich-730	147	20	m.	m.	NOUN
biomedich-730	147	21	i.	i.	PROPN
biomedich-730	147	22	,	,	PUNCT
biomedich-730	147	23	iqbal	iqbal	PROPN
biomedich-730	147	24	,	,	PUNCT
biomedich-730	147	25	z.	z.	PROPN
biomedich-730	147	26	,	,	PUNCT
biomedich-730	147	27	ali	ali	PROPN
biomedich-730	147	28	,	,	PUNCT
biomedich-730	147	29	t.	t.	PROPN
biomedich-730	147	30	,	,	PUNCT
biomedich-730	147	31	ullah	ullah	PROPN
biomedich-730	147	32	,	,	PUNCT
biomedich-730	147	33	r.	r.	PROPN
biomedich-730	147	34	,	,	PUNCT
biomedich-730	147	35	&	&	CCONJ
biomedich-730	147	36	bari	bari	NOUN
biomedich-730	147	37	,	,	PUNCT
biomedich-730	147	38	a.	a.	NOUN
biomedich-730	147	39	(	(	PUNCT
biomedich-730	147	40	2024	2024	NUM
biomedich-730	147	41	)	)	PUNCT
biomedich-730	147	42	.	.	PUNCT
biomedich-730	148	1	in	in	ADP
biomedich-730	148	2	silico	silico	NOUN
biomedich-730	148	3	homology	homology	NOUN
biomedich-730	148	4	modeling	modeling	NOUN
biomedich-730	148	5	of	of	ADP
biomedich-730	148	6	dengue	dengue	PROPN
biomedich-730	148	7	virus	virus	PROPN
biomedich-730	148	8	non	non	ADJ
biomedich-730	148	9	-	-	ADJ
biomedich-730	148	10	structural	structural	ADJ
biomedich-730	148	11	4b	4b	PROPN
biomedich-730	148	12	(	(	PUNCT
biomedich-730	148	13	ns4b	ns4b	NOUN
biomedich-730	148	14	)	)	PUNCT
biomedich-730	148	15	protein	protein	NOUN
biomedich-730	148	16	and	and	CCONJ
biomedich-730	148	17	its	its	PRON
biomedich-730	148	18	molecular	molecular	ADJ
biomedich-730	148	19	docking	docking	NOUN
biomedich-730	148	20	studies	study	NOUN
biomedich-730	148	21	using	use	VERB
biomedich-730	148	22	triterpenoids	triterpenoids	PROPN
biomedich-730	148	23	.	.	PUNCT
biomedich-730	149	1	bmc	bmc	ADJ
biomedich-730	149	2	infectious	infectious	ADJ
biomedich-730	149	3	diseases	disease	NOUN
biomedich-730	149	4	,	,	PUNCT
biomedich-730	149	5	24(1	24(1	NUM
biomedich-730	149	6	)	)	PUNCT
biomedich-730	149	7	,	,	PUNCT
biomedich-730	149	8	688	688	NUM
biomedich-730	149	9	.	.	PUNCT
biomedich-730	150	1	https://doi.org/10.1186/s12879-02409578-5	https://doi.org/10.1186/s12879-02409578-5	PROPN
biomedich-730	150	2	charchar	charchar	PROPN
biomedich-730	150	3	,	,	PUNCT
biomedich-730	150	4	f.	f.	PROPN
biomedich-730	150	5	j.	j.	PROPN
biomedich-730	150	6	,	,	PUNCT
biomedich-730	150	7	prestes	preste	NOUN
biomedich-730	150	8	,	,	PUNCT
biomedich-730	150	9	p.	p.	PROPN
biomedich-730	150	10	r.	r.	PROPN
biomedich-730	150	11	,	,	PUNCT
biomedich-730	150	12	mills	mill	NOUN
biomedich-730	150	13	,	,	PUNCT
biomedich-730	150	14	c.	c.	PROPN
biomedich-730	150	15	,	,	PUNCT
biomedich-730	150	16	ching	ching	PROPN
biomedich-730	150	17	,	,	PUNCT
biomedich-730	150	18	s.	s.	PROPN
biomedich-730	150	19	m.	m.	PROPN
biomedich-730	150	20	,	,	PUNCT
biomedich-730	150	21	neupane	neupane	PROPN
biomedich-730	150	22	,	,	PUNCT
biomedich-730	150	23	d.	d.	PROPN
biomedich-730	150	24	,	,	PUNCT
biomedich-730	150	25	marques	marques	PROPN
biomedich-730	150	26	,	,	PUNCT
biomedich-730	150	27	f.	f.	PROPN
biomedich-730	150	28	z.	z.	PROPN
biomedich-730	150	29	,	,	PUNCT
biomedich-730	150	30	sharman	sharman	PROPN
biomedich-730	150	31	,	,	PUNCT
biomedich-730	150	32	j.	j.	PROPN
biomedich-730	150	33	e.	e.	PROPN
biomedich-730	150	34	,	,	PUNCT
biomedich-730	150	35	vogt	vogt	PROPN
biomedich-730	150	36	,	,	PUNCT
biomedich-730	150	37	l.	l.	PROPN
biomedich-730	150	38	,	,	PUNCT
biomedich-730	150	39	burrell	burrell	PROPN
biomedich-730	150	40	,	,	PUNCT
biomedich-730	150	41	l.	l.	PROPN
biomedich-730	150	42	m.	m.	PROPN
biomedich-730	150	43	,	,	PUNCT
biomedich-730	150	44	korostovtseva	korostovtseva	PROPN
biomedich-730	150	45	,	,	PUNCT
biomedich-730	150	46	l.	l.	PROPN
biomedich-730	150	47	,	,	PUNCT
biomedich-730	150	48	zec	zec	PROPN
biomedich-730	150	49	,	,	PUNCT
biomedich-730	150	50	m.	m.	NOUN
biomedich-730	150	51	,	,	PUNCT
biomedich-730	150	52	patil	patil	PROPN
biomedich-730	150	53	,	,	PUNCT
biomedich-730	150	54	m.	m.	NOUN
biomedich-730	150	55	,	,	PUNCT
biomedich-730	150	56	schultz	schultz	PROPN
biomedich-730	150	57	,	,	PUNCT
biomedich-730	150	58	m.	m.	NOUN
biomedich-730	150	59	g.	g.	PROPN
biomedich-730	150	60	,	,	PUNCT
biomedich-730	150	61	wallen	wallen	PROPN
biomedich-730	150	62	,	,	PUNCT
biomedich-730	150	63	m.	m.	NOUN
biomedich-730	150	64	p.	p.	PROPN
biomedich-730	150	65	,	,	PUNCT
biomedich-730	150	66	renna	renna	PROPN
biomedich-730	150	67	,	,	PUNCT
biomedich-730	150	68	n.	n.	PROPN
biomedich-730	150	69	f.	f.	PROPN
biomedich-730	150	70	,	,	PUNCT
biomedich-730	150	71	islam	islam	PROPN
biomedich-730	150	72	,	,	PUNCT
biomedich-730	150	73	s.	s.	PROPN
biomedich-730	150	74	m.	m.	PROPN
biomedich-730	150	75	s.	s.	PROPN
biomedich-730	150	76	,	,	PUNCT
biomedich-730	150	77	hiremath	hiremath	PROPN
biomedich-730	150	78	,	,	PUNCT
biomedich-730	150	79	s.	s.	PROPN
biomedich-730	150	80	,	,	PUNCT
biomedich-730	150	81	gyeltshen	gyeltshen	NOUN
biomedich-730	150	82	,	,	PUNCT
biomedich-730	150	83	t.	t.	PROPN
biomedich-730	150	84	,	,	PUNCT
biomedich-730	150	85	chia	chia	PROPN
biomedich-730	150	86	,	,	PUNCT
biomedich-730	150	87	y.	y.	PROPN
biomedich-730	150	88	c.	c.	PROPN
biomedich-730	150	89	,	,	PUNCT
biomedich-730	150	90	gupta	gupta	PROPN
biomedich-730	150	91	,	,	PUNCT
biomedich-730	150	92	a.	a.	NOUN
biomedich-730	150	93	,	,	PUNCT
biomedich-730	150	94	…	…	PUNCT
biomedich-730	150	95	tomaszewski	tomaszewski	ADJ
biomedich-730	150	96	,	,	PUNCT
biomedich-730	150	97	m.	m.	NOUN
biomedich-730	150	98	(	(	PUNCT
biomedich-730	150	99	2024	2024	NUM
biomedich-730	150	100	)	)	PUNCT
biomedich-730	150	101	.	.	PUNCT
biomedich-730	151	1	lifestyle	lifestyle	PROPN
biomedich-730	151	2	management	management	NOUN
biomedich-730	151	3	of	of	ADP
biomedich-730	151	4	hypertension	hypertension	NOUN
biomedich-730	151	5	:	:	PUNCT
biomedich-730	151	6	international	international	ADJ
biomedich-730	151	7	society	society	NOUN
biomedich-730	151	8	of	of	ADP
biomedich-730	151	9	hypertension	hypertension	NOUN
biomedich-730	151	10	position	position	NOUN
biomedich-730	151	11	paper	paper	NOUN
biomedich-730	151	12	endorsed	endorse	VERB
biomedich-730	151	13	by	by	ADP
biomedich-730	151	14	the	the	DET
biomedich-730	151	15	world	world	NOUN
biomedich-730	151	16	hypertension	hypertension	PROPN
biomedich-730	151	17	league	league	PROPN
biomedich-730	151	18	and	and	CCONJ
biomedich-730	151	19	european	european	ADJ
biomedich-730	151	20	society	society	NOUN
biomedich-730	151	21	of	of	ADP
biomedich-730	151	22	hypertension	hypertension	NOUN
biomedich-730	151	23	.	.	PUNCT
biomedich-730	152	1	journal	journal	NOUN
biomedich-730	152	2	of	of	ADP
biomedich-730	152	3	hypertension	hypertension	NOUN
biomedich-730	152	4	,	,	PUNCT
biomedich-730	152	5	42(1	42(1	NOUN
biomedich-730	152	6	)	)	PUNCT
biomedich-730	152	7	,	,	PUNCT
biomedich-730	152	8	23–49	23–49	NUM
biomedich-730	152	9	.	.	PUNCT
biomedich-730	153	1	https://doi.org/10.1097/hjh.0000000000003563	https://doi.org/10.1097/hjh.0000000000003563	PROPN
biomedich-730	153	2	chen	chen	PROPN
biomedich-730	153	3	,	,	PUNCT
biomedich-730	153	4	r.	r.	PROPN
biomedich-730	153	5	,	,	PUNCT
biomedich-730	153	6	suchard	suchard	NOUN
biomedich-730	153	7	,	,	PUNCT
biomedich-730	153	8	m.	m.	NOUN
biomedich-730	153	9	a.	a.	PROPN
biomedich-730	153	10	,	,	PUNCT
biomedich-730	153	11	krumholz	krumholz	PROPN
biomedich-730	153	12	,	,	PUNCT
biomedich-730	153	13	h.	h.	PROPN
biomedich-730	153	14	m.	m.	PROPN
biomedich-730	153	15	,	,	PUNCT
biomedich-730	153	16	schuemie	schuemie	NOUN
biomedich-730	153	17	,	,	PUNCT
biomedich-730	153	18	m.	m.	NOUN
biomedich-730	153	19	j.	j.	PROPN
biomedich-730	153	20	,	,	PUNCT
biomedich-730	153	21	shea	shea	PROPN
biomedich-730	153	22	,	,	PUNCT
biomedich-730	153	23	s.	s.	PROPN
biomedich-730	153	24	,	,	PUNCT
biomedich-730	153	25	duke	duke	PROPN
biomedich-730	153	26	,	,	PUNCT
biomedich-730	153	27	j.	j.	PROPN
biomedich-730	153	28	,	,	PUNCT
biomedich-730	153	29	pratt	pratt	PROPN
biomedich-730	153	30	,	,	PUNCT
biomedich-730	153	31	n.	n.	PROPN
biomedich-730	153	32	,	,	PUNCT
biomedich-730	153	33	reich	reich	PROPN
biomedich-730	153	34	,	,	PUNCT
biomedich-730	153	35	c.	c.	PROPN
biomedich-730	153	36	g.	g.	PROPN
biomedich-730	153	37	,	,	PUNCT
biomedich-730	153	38	madigan	madigan	PROPN
biomedich-730	153	39	,	,	PUNCT
biomedich-730	153	40	d.	d.	PROPN
biomedich-730	153	41	,	,	PUNCT
biomedich-730	153	42	you	you	PRON
biomedich-730	153	43	,	,	PUNCT
biomedich-730	153	44	s.	s.	PROPN
biomedich-730	153	45	c.	c.	PROPN
biomedich-730	153	46	,	,	PUNCT
biomedich-730	153	47	ryan	ryan	PROPN
biomedich-730	153	48	,	,	PUNCT
biomedich-730	153	49	p.	p.	PROPN
biomedich-730	153	50	b.	b.	PROPN
biomedich-730	153	51	,	,	PUNCT
biomedich-730	153	52	&	&	CCONJ
biomedich-730	153	53	hripcsak	hripcsak	PROPN
biomedich-730	153	54	,	,	PUNCT
biomedich-730	153	55	g.	g.	PROPN
biomedich-730	153	56	(	(	PUNCT
biomedich-730	153	57	2021	2021	NUM
biomedich-730	153	58	)	)	PUNCT
biomedich-730	153	59	.	.	PUNCT
biomedich-730	154	1	comparative	comparative	ADJ
biomedich-730	154	2	firstline	firstline	PROPN
biomedich-730	154	3	effectiveness	effectiveness	NOUN
biomedich-730	154	4	and	and	CCONJ
biomedich-730	154	5	safety	safety	NOUN
biomedich-730	154	6	of	of	ADP
biomedich-730	154	7	ace	ace	NOUN
biomedich-730	154	8	(	(	PUNCT
biomedich-730	154	9	angiotensinconverting	angiotensinconverte	VERB
biomedich-730	154	10	enzyme	enzyme	NOUN
biomedich-730	154	11	)	)	PUNCT
biomedich-730	154	12	inhibitors	inhibitor	NOUN
biomedich-730	154	13	and	and	CCONJ
biomedich-730	154	14	angiotensin	angiotensin	NOUN
biomedich-730	154	15	receptor	receptor	NOUN
biomedich-730	154	16	blockers	blocker	NOUN
biomedich-730	154	17	:	:	PUNCT
biomedich-730	154	18	a	a	DET
biomedich-730	154	19	multinational	multinational	ADJ
biomedich-730	154	20	cohort	cohort	NOUN
biomedich-730	154	21	study	study	NOUN
biomedich-730	154	22	.	.	PUNCT
biomedich-730	155	1	hypertension	hypertension	NOUN
biomedich-730	155	2	(	(	PUNCT
biomedich-730	155	3	dallas	dallas	PROPN
biomedich-730	155	4	,	,	PUNCT
biomedich-730	155	5	tex	tex	PROPN
biomedich-730	155	6	.	.	PROPN
biomedich-730	155	7	:	:	PUNCT
biomedich-730	155	8	1979	1979	NUM
biomedich-730	155	9	)	)	PUNCT
biomedich-730	155	10	,	,	PUNCT
biomedich-730	155	11	78(3	78(3	NUM
biomedich-730	155	12	)	)	PUNCT
biomedich-730	155	13	,	,	PUNCT
biomedich-730	155	14	591–603	591–603	NUM
biomedich-730	155	15	.	.	PUNCT
biomedich-730	156	1	https://doi.org/10.1161/hypertensionaha.120.16667	https://doi.org/10.1161/hypertensionaha.120.16667	PROPN
biomedich-730	156	2	daina	daina	PROPN
biomedich-730	156	3	,	,	PUNCT
biomedich-730	156	4	a.	a.	PROPN
biomedich-730	156	5	,	,	PUNCT
biomedich-730	156	6	michielin	michielin	PROPN
biomedich-730	156	7	,	,	PUNCT
biomedich-730	156	8	o.	o.	PROPN
biomedich-730	156	9	,	,	PUNCT
biomedich-730	156	10	&	&	CCONJ
biomedich-730	156	11	zoete	zoete	PROPN
biomedich-730	156	12	,	,	PUNCT
biomedich-730	156	13	v.	v.	PROPN
biomedich-730	156	14	(	(	PUNCT
biomedich-730	156	15	2017	2017	NUM
biomedich-730	156	16	)	)	PUNCT
biomedich-730	156	17	.	.	PUNCT
biomedich-730	157	1	swissadme	swissadme	NOUN
biomedich-730	157	2	:	:	PUNCT
biomedich-730	157	3	a	a	DET
biomedich-730	157	4	free	free	ADJ
biomedich-730	157	5	web	web	NOUN
biomedich-730	157	6	tool	tool	NOUN
biomedich-730	157	7	to	to	PART
biomedich-730	157	8	evaluate	evaluate	VERB
biomedich-730	157	9	pharmacokinetics	pharmacokinetic	NOUN
biomedich-730	157	10	,	,	PUNCT
biomedich-730	157	11	drug	drug	NOUN
biomedich-730	157	12	-	-	PUNCT
biomedich-730	157	13	likeness	likeness	NOUN
biomedich-730	157	14	and	and	CCONJ
biomedich-730	157	15	medicinal	medicinal	ADJ
biomedich-730	157	16	chemistry	chemistry	NOUN
biomedich-730	157	17	friendliness	friendliness	NOUN
biomedich-730	157	18	of	of	ADP
biomedich-730	157	19	small	small	ADJ
biomedich-730	157	20	molecules	molecule	NOUN
biomedich-730	157	21	.	.	PUNCT
biomedich-730	158	1	scientific	scientific	ADJ
biomedich-730	158	2	reports	report	NOUN
biomedich-730	158	3	,	,	PUNCT
biomedich-730	158	4	7	7	NUM
biomedich-730	158	5	,	,	PUNCT
biomedich-730	158	6	42717	42717	NUM
biomedich-730	158	7	.	.	PUNCT
biomedich-730	159	1	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
biomedich-730	159	2	de	de	PROPN
biomedich-730	159	3	vries	vries	PROPN
biomedich-730	159	4	a.	a.	PROPN
biomedich-730	159	5	a.	a.	PROPN
biomedich-730	159	6	f.	f.	PROPN
biomedich-730	159	7	(	(	PUNCT
biomedich-730	159	8	2020	2020	NUM
biomedich-730	159	9	)	)	PUNCT
biomedich-730	159	10	.	.	PUNCT
biomedich-730	160	1	renin	renin	ADJ
biomedich-730	160	2	-	-	PUNCT
biomedich-730	160	3	angiotensin	angiotensin	NOUN
biomedich-730	160	4	system	system	NOUN
biomedich-730	160	5	inhibition	inhibition	NOUN
biomedich-730	160	6	in	in	ADP
biomedich-730	160	7	covid-19	covid-19	PROPN
biomedich-730	160	8	patients	patient	NOUN
biomedich-730	160	9	.	.	PUNCT
biomedich-730	161	1	netherlands	netherlands	PROPN
biomedich-730	161	2	heart	heart	PROPN
biomedich-730	161	3	journal	journal	PROPN
biomedich-730	161	4	:	:	PUNCT
biomedich-730	161	5	monthly	monthly	ADJ
biomedich-730	161	6	journal	journal	NOUN
biomedich-730	161	7	of	of	ADP
biomedich-730	161	8	the	the	DET
biomedich-730	161	9	netherlands	netherlands	PROPN
biomedich-730	161	10	society	society	PROPN
biomedich-730	161	11	of	of	ADP
biomedich-730	161	12	cardiology	cardiology	NOUN
biomedich-730	161	13	and	and	CCONJ
biomedich-730	161	14	the	the	DET
biomedich-730	161	15	netherlands	netherlands	PROPN
biomedich-730	161	16	heart	heart	PROPN
biomedich-730	161	17	foundation	foundation	PROPN
biomedich-730	161	18	,	,	PUNCT
biomedich-730	161	19	28(7	28(7	NUM
biomedich-730	161	20	-	-	SYM
biomedich-730	161	21	8)	8)	NUM
biomedich-730	161	22	,	,	PUNCT
biomedich-730	161	23	396–405	396–405	NUM
biomedich-730	161	24	.	.	PUNCT
biomedich-730	162	1	https://doi.org/10.1007/s12471-020-01439-5	https://doi.org/10.1007/s12471-020-01439-5	NUM
biomedich-730	162	2	deka	deka	PROPN
biomedich-730	162	3	,	,	PUNCT
biomedich-730	162	4	h.	h.	PROPN
biomedich-730	162	5	,	,	PUNCT
biomedich-730	162	6	sarmah	sarmah	PROPN
biomedich-730	162	7	,	,	PUNCT
biomedich-730	162	8	r.	r.	PROPN
biomedich-730	162	9	,	,	PUNCT
biomedich-730	162	10	sharma	sharma	PROPN
biomedich-730	162	11	,	,	PUNCT
biomedich-730	162	12	a.	a.	PROPN
biomedich-730	162	13	,	,	PUNCT
biomedich-730	162	14	&	&	CCONJ
biomedich-730	162	15	biswas	biswas	PROPN
biomedich-730	162	16	,	,	PUNCT
biomedich-730	162	17	s.	s.	PROPN
biomedich-730	162	18	(	(	PUNCT
biomedich-730	162	19	2015	2015	NUM
biomedich-730	162	20	)	)	PUNCT
biomedich-730	162	21	.	.	PUNCT
biomedich-730	163	1	modelling	modelling	NOUN
biomedich-730	163	2	and	and	CCONJ
biomedich-730	163	3	characterization	characterization	NOUN
biomedich-730	163	4	of	of	ADP
biomedich-730	163	5	glial	glial	ADJ
biomedich-730	163	6	fibrillary	fibrillary	ADJ
biomedich-730	163	7	acidic	acidic	ADJ
biomedich-730	163	8	protein	protein	NOUN
biomedich-730	163	9	.	.	PUNCT
biomedich-730	164	1	bioinformation	bioinformation	NOUN
biomedich-730	164	2	,	,	PUNCT
biomedich-730	164	3	11(8	11(8	PROPN
biomedich-730	164	4	)	)	PUNCT
biomedich-730	164	5	,	,	PUNCT
biomedich-730	164	6	393–400	393–400	NUM
biomedich-730	164	7	.	.	PUNCT
biomedich-730	165	1	https://doi.org/10.6026/97320630011393	https://doi.org/10.6026/97320630011393	NOUN
biomedich-730	165	2	gfeller	gfeller	NOUN
biomedich-730	165	3	,	,	PUNCT
biomedich-730	165	4	d.	d.	PROPN
biomedich-730	165	5	,	,	PUNCT
biomedich-730	165	6	grosdidier	grosdidier	NOUN
biomedich-730	165	7	,	,	PUNCT
biomedich-730	165	8	a.	a.	NOUN
biomedich-730	165	9	,	,	PUNCT
biomedich-730	165	10	wirth	wirth	PROPN
biomedich-730	165	11	,	,	PUNCT
biomedich-730	165	12	m.	m.	NOUN
biomedich-730	165	13	,	,	PUNCT
biomedich-730	165	14	daina	daina	PROPN
biomedich-730	165	15	,	,	PUNCT
biomedich-730	165	16	a.	a.	PROPN
biomedich-730	165	17	,	,	PUNCT
biomedich-730	165	18	michielin	michielin	PROPN
biomedich-730	165	19	,	,	PUNCT
biomedich-730	165	20	o.	o.	PROPN
biomedich-730	165	21	,	,	PUNCT
biomedich-730	165	22	&	&	CCONJ
biomedich-730	165	23	zoete	zoete	PROPN
biomedich-730	165	24	,	,	PUNCT
biomedich-730	165	25	v.	v.	PROPN
biomedich-730	165	26	(	(	PUNCT
biomedich-730	165	27	2014	2014	NUM
biomedich-730	165	28	)	)	PUNCT
biomedich-730	165	29	.	.	PUNCT
biomedich-730	166	1	swisstargetprediction	swisstargetprediction	NOUN
biomedich-730	166	2	:	:	PUNCT
biomedich-730	166	3	a	a	DET
biomedich-730	166	4	web	web	NOUN
biomedich-730	166	5	server	server	NOUN
biomedich-730	166	6	for	for	ADP
biomedich-730	166	7	target	target	NOUN
biomedich-730	166	8	prediction	prediction	NOUN
biomedich-730	166	9	of	of	ADP
biomedich-730	166	10	bioactive	bioactive	ADJ
biomedich-730	166	11	small	small	ADJ
biomedich-730	166	12	molecules	molecule	NOUN
biomedich-730	166	13	.	.	PUNCT
biomedich-730	167	1	nucleic	nucleic	ADJ
biomedich-730	167	2	acids	acid	NOUN
biomedich-730	167	3	research	research	NOUN
biomedich-730	167	4	,	,	PUNCT
biomedich-730	167	5	42(web	42(web	NOUN
biomedich-730	167	6	server	server	NOUN
biomedich-730	167	7	issue	issue	NOUN
biomedich-730	167	8	)	)	PUNCT
biomedich-730	167	9	,	,	PUNCT
biomedich-730	167	10	w32	w32	NOUN
biomedich-730	167	11	–	–	PUNCT
biomedich-730	167	12	w38	w38	ADJ
biomedich-730	167	13	.	.	PUNCT
biomedich-730	168	1	https://doi.org/10.1093/nar/gku293	https://doi.org/10.1093/nar/gku293	NOUN
biomedich-730	168	2	gunasekaran	gunasekaran	NOUN
biomedich-730	168	3	,	,	PUNCT
biomedich-730	168	4	k.	k.	PROPN
biomedich-730	168	5	,	,	PUNCT
biomedich-730	168	6	ramakrishnan	ramakrishnan	PROPN
biomedich-730	168	7	,	,	PUNCT
biomedich-730	168	8	c.	c.	PROPN
biomedich-730	168	9	,	,	PUNCT
biomedich-730	168	10	&	&	CCONJ
biomedich-730	168	11	balaram	balaram	PROPN
biomedich-730	168	12	,	,	PUNCT
biomedich-730	168	13	p.	p.	NOUN
biomedich-730	168	14	(	(	PUNCT
biomedich-730	168	15	1996	1996	NUM
biomedich-730	168	16	)	)	PUNCT
biomedich-730	168	17	.	.	PUNCT
biomedich-730	169	1	disallowed	disallow	VERB
biomedich-730	169	2	ramachandran	ramachandran	NOUN
biomedich-730	169	3	conformations	conformation	NOUN
biomedich-730	169	4	of	of	ADP
biomedich-730	169	5	amino	amino	NOUN
biomedich-730	169	6	acid	acid	NOUN
biomedich-730	169	7	residues	residue	NOUN
biomedich-730	169	8	in	in	ADP
biomedich-730	169	9	protein	protein	NOUN
biomedich-730	169	10	structures	structure	NOUN
biomedich-730	169	11	.	.	PUNCT
biomedich-730	170	1	journal	journal	NOUN
biomedich-730	170	2	of	of	ADP
biomedich-730	170	3	molecular	molecular	ADJ
biomedich-730	170	4	biology	biology	NOUN
biomedich-730	170	5	,	,	PUNCT
biomedich-730	170	6	264(1	264(1	NUM
biomedich-730	170	7	)	)	PUNCT
biomedich-730	170	8	,	,	PUNCT
biomedich-730	170	9	191–198	191–198	NUM
biomedich-730	170	10	.	.	PUNCT
biomedich-730	171	1	https://doi.org/10.1006/jmbi.1996.0633	https://doi.org/10.1006/jmbi.1996.0633	PROPN
biomedich-730	171	2	hamid	hamid	PROPN
biomedich-730	171	3	,	,	PUNCT
biomedich-730	171	4	m.	m.	NOUN
biomedich-730	171	5	,	,	PUNCT
biomedich-730	171	6	habib	habib	PROPN
biomedich-730	171	7	,	,	PUNCT
biomedich-730	171	8	u.	u.	PROPN
biomedich-730	171	9	,	,	PUNCT
biomedich-730	171	10	batool	batool	NOUN
biomedich-730	171	11	,	,	PUNCT
biomedich-730	171	12	j.	j.	PROPN
biomedich-730	171	13	,	,	PUNCT
biomedich-730	171	14	qaisar	qaisar	PROPN
biomedich-730	171	15	,	,	PUNCT
biomedich-730	171	16	a.	a.	PROPN
biomedich-730	171	17	,	,	PUNCT
biomedich-730	171	18	&	&	CCONJ
biomedich-730	171	19	zafar	zafar	PROPN
biomedich-730	171	20	,	,	PUNCT
biomedich-730	171	21	r.	r.	PROPN
biomedich-730	171	22	(	(	PUNCT
biomedich-730	171	23	2021	2021	NUM
biomedich-730	171	24	)	)	PUNCT
biomedich-730	171	25	.	.	PUNCT
biomedich-730	172	1	identification	identification	NOUN
biomedich-730	172	2	and	and	CCONJ
biomedich-730	172	3	computational	computational	ADJ
biomedich-730	172	4	analysis	analysis	NOUN
biomedich-730	172	5	of	of	ADP
biomedich-730	172	6	3d	3d	NOUN
biomedich-730	172	7	-	-	PUNCT
biomedich-730	172	8	structure	structure	NOUN
biomedich-730	172	9	of	of	ADP
biomedich-730	172	10	mocs1	mocs1	PROPN
biomedich-730	172	11	.	.	PUNCT
biomedich-730	173	1	research	research	NOUN
biomedich-730	173	2	square	square	PROPN
biomedich-730	173	3	.	.	PUNCT
biomedich-730	174	1	https://doi.org/10.21203/rs.3.rs473901/v1	https://doi.org/10.21203/rs.3.rs473901/v1	PROPN
biomedich-730	174	2	hermida	hermida	PROPN
biomedich-730	174	3	,	,	PUNCT
biomedich-730	174	4	r.	r.	PROPN
biomedich-730	174	5	c.	c.	PROPN
biomedich-730	174	6	,	,	PUNCT
biomedich-730	174	7	ayala	ayala	PROPN
biomedich-730	174	8	,	,	PUNCT
biomedich-730	174	9	d.	d.	PROPN
biomedich-730	174	10	e.	e.	PROPN
biomedich-730	174	11	,	,	PUNCT
biomedich-730	174	12	fernández	fernández	PROPN
biomedich-730	174	13	,	,	PUNCT
biomedich-730	174	14	j.	j.	PROPN
biomedich-730	174	15	r.	r.	PROPN
biomedich-730	174	16	,	,	PUNCT
biomedich-730	174	17	portaluppi	portaluppi	PROPN
biomedich-730	174	18	,	,	PUNCT
biomedich-730	174	19	f.	f.	PROPN
biomedich-730	174	20	,	,	PUNCT
biomedich-730	174	21	fabbian	fabbian	NOUN
biomedich-730	174	22	,	,	PUNCT
biomedich-730	174	23	f.	f.	PROPN
biomedich-730	174	24	,	,	PUNCT
biomedich-730	174	25	&	&	CCONJ
biomedich-730	174	26	smolensky	smolensky	PROPN
biomedich-730	174	27	,	,	PUNCT
biomedich-730	174	28	m.	m.	NOUN
biomedich-730	174	29	h.	h.	PROPN
biomedich-730	174	30	(	(	PUNCT
biomedich-730	174	31	2011	2011	NUM
biomedich-730	174	32	)	)	PUNCT
biomedich-730	174	33	.	.	PUNCT
biomedich-730	175	1	circadian	circadian	ADJ
biomedich-730	175	2	rhythms	rhythm	NOUN
biomedich-730	175	3	in	in	ADP
biomedich-730	175	4	blood	blood	NOUN
biomedich-730	175	5	pressure	pressure	NOUN
biomedich-730	175	6	regulation	regulation	NOUN
biomedich-730	175	7	and	and	CCONJ
biomedich-730	175	8	optimization	optimization	NOUN
biomedich-730	175	9	of	of	ADP
biomedich-730	175	10	hypertension	hypertension	NOUN
biomedich-730	175	11	treatment	treatment	NOUN
biomedich-730	175	12	with	with	ADP
biomedich-730	175	13	ace	ace	NOUN
biomedich-730	175	14	inhibitor	inhibitor	NOUN
biomedich-730	175	15	and	and	CCONJ
biomedich-730	175	16	arb	arb	NOUN
biomedich-730	175	17	medications	medication	NOUN
biomedich-730	175	18	.	.	PUNCT
biomedich-730	176	1	american	american	ADJ
biomedich-730	176	2	journal	journal	PROPN
biomedich-730	176	3	of	of	ADP
biomedich-730	176	4	hypertension	hypertension	NOUN
biomedich-730	176	5	,	,	PUNCT
biomedich-730	176	6	24(4	24(4	NOUN
biomedich-730	176	7	)	)	PUNCT
biomedich-730	176	8	,	,	PUNCT
biomedich-730	176	9	383–391	383–391	NUM
biomedich-730	176	10	.	.	PUNCT
biomedich-730	176	11	https://doi.org/10.1038/ajh.2010.217	https://doi.org/10.1038/ajh.2010.217	NOUN
biomedich-730	176	12	ismail	ismail	PROPN
biomedich-730	176	13	,	,	PUNCT
biomedich-730	176	14	h.	h.	PROPN
biomedich-730	176	15	,	,	PUNCT
biomedich-730	176	16	khalid	khalid	PROPN
biomedich-730	176	17	,	,	PUNCT
biomedich-730	176	18	d.	d.	PROPN
biomedich-730	176	19	,	,	PUNCT
biomedich-730	176	20	waseem	waseem	PROPN
biomedich-730	176	21	,	,	PUNCT
biomedich-730	176	22	d.	d.	PROPN
biomedich-730	176	23	,	,	PUNCT
biomedich-730	176	24	ijaz	ijaz	PROPN
biomedich-730	176	25	,	,	PUNCT
biomedich-730	176	26	m.	m.	NOUN
biomedich-730	176	27	u.	u.	PROPN
biomedich-730	176	28	,	,	PUNCT
biomedich-730	176	29	dilshad	dilshad	PROPN
biomedich-730	176	30	,	,	PUNCT
biomedich-730	176	31	e.	e.	PROPN
biomedich-730	176	32	,	,	PUNCT
biomedich-730	176	33	haq	haq	PROPN
biomedich-730	176	34	,	,	PUNCT
biomedich-730	176	35	i.	i.	PROPN
biomedich-730	176	36	u.	u.	PROPN
biomedich-730	176	37	,	,	PUNCT
biomedich-730	176	38	bhatti	bhatti	PROPN
biomedich-730	176	39	,	,	PUNCT
biomedich-730	176	40	m.	m.	NOUN
biomedich-730	176	41	z.	z.	PROPN
biomedich-730	176	42	,	,	PUNCT
biomedich-730	176	43	anwaar	anwaar	NOUN
biomedich-730	176	44	,	,	PUNCT
biomedich-730	176	45	s.	s.	PROPN
biomedich-730	176	46	,	,	PUNCT
biomedich-730	176	47	ahmed	ahmed	PROPN
biomedich-730	176	48	,	,	PUNCT
biomedich-730	176	49	m.	m.	NOUN
biomedich-730	176	50	,	,	PUNCT
biomedich-730	176	51	&	&	CCONJ
biomedich-730	176	52	saleem	saleem	PROPN
biomedich-730	176	53	,	,	PUNCT
biomedich-730	176	54	s.	s.	PROPN
biomedich-730	176	55	(	(	PUNCT
biomedich-730	176	56	2023	2023	NUM
biomedich-730	176	57	)	)	PUNCT
biomedich-730	176	58	.	.	PUNCT
biomedich-730	177	1	bioassays	bioassays	PROPN
biomedich-730	177	2	guided	guide	VERB
biomedich-730	177	3	isolation	isolation	NOUN
biomedich-730	177	4	of	of	ADP
biomedich-730	177	5	berberine	berberine	NOUN
biomedich-730	177	6	from	from	ADP
biomedich-730	177	7	berberis	berberis	PROPN
biomedich-730	177	8	lycium	lycium	NOUN
biomedich-730	177	9	and	and	CCONJ
biomedich-730	177	10	its	its	PRON
biomedich-730	177	11	neuroprotective	neuroprotective	ADJ
biomedich-730	177	12	role	role	NOUN
biomedich-730	177	13	in	in	ADP
biomedich-730	177	14	aluminium	aluminium	NOUN
biomedich-730	177	15	chloride	chloride	NOUN
biomedich-730	177	16	induced	induce	VERB
biomedich-730	177	17	rat	rat	NOUN
biomedich-730	177	18	model	model	NOUN
biomedich-730	177	19	of	of	ADP
biomedich-730	177	20	alzheimer	alzheimer	PROPN
biomedich-730	177	21	's	's	PART
biomedich-730	177	22	disease	disease	NOUN
biomedich-730	177	23	combined	combine	VERB
biomedich-730	177	24	with	with	ADP
biomedich-730	177	25	insilico	insilico	NOUN
biomedich-730	177	26	molecular	molecular	ADJ
biomedich-730	177	27	docking	docking	NOUN
biomedich-730	177	28	.	.	PUNCT
biomedich-730	178	1	plos	plos	PROPN
biomedich-730	178	2	one	one	NUM
biomedich-730	178	3	,	,	PUNCT
biomedich-730	178	4	18(11	18(11	NUM
biomedich-730	178	5	)	)	PUNCT
biomedich-730	178	6	,	,	PUNCT
biomedich-730	178	7	e0286349	e0286349	PROPN
biomedich-730	178	8	.	.	PUNCT
biomedich-730	179	1	https://doi.org/10.1371/journal.pone.0286349	https://doi.org/10.1371/journal.pone.0286349	PROPN
biomedich-730	179	2	joyner	joyner	PROPN
biomedich-730	179	3	p.	p.	PROPN
biomedich-730	179	4	m.	m.	NOUN
biomedich-730	179	5	(	(	PUNCT
biomedich-730	179	6	2021	2021	NUM
biomedich-730	179	7	)	)	PUNCT
biomedich-730	179	8	.	.	PUNCT
biomedich-730	180	1	protein	protein	NOUN
biomedich-730	180	2	adducts	adduct	NOUN
biomedich-730	180	3	and	and	CCONJ
biomedich-730	180	4	protein	protein	NOUN
biomedich-730	180	5	oxidation	oxidation	NOUN
biomedich-730	180	6	as	as	ADP
biomedich-730	180	7	molecular	molecular	ADJ
biomedich-730	180	8	mechanisms	mechanism	NOUN
biomedich-730	180	9	of	of	ADP
biomedich-730	180	10	flavonoid	flavonoid	PROPN
biomedich-730	180	11	bioactivity	bioactivity	NOUN
biomedich-730	180	12	.	.	PUNCT
biomedich-730	181	1	molecules	molecule	NOUN
biomedich-730	181	2	(	(	PUNCT
biomedich-730	181	3	basel	basel	PROPN
biomedich-730	181	4	,	,	PUNCT
biomedich-730	181	5	switzerland	switzerland	PROPN
biomedich-730	181	6	)	)	PUNCT
biomedich-730	181	7	,	,	PUNCT
biomedich-730	181	8	26(16	26(16	NUM
biomedich-730	181	9	)	)	PUNCT
biomedich-730	181	10	,	,	PUNCT
biomedich-730	181	11	5102	5102	NUM
biomedich-730	181	12	.	.	PUNCT
biomedich-730	182	1	https://doi.org/10.3390/molecules26165102	https://doi.org/10.3390/molecules26165102	PROPN
biomedich-730	182	2	kumar	kumar	PROPN
biomedich-730	182	3	,	,	PUNCT
biomedich-730	182	4	s.	s.	PROPN
biomedich-730	182	5	,	,	PUNCT
biomedich-730	182	6	&	&	CCONJ
biomedich-730	182	7	pandey	pandey	PROPN
biomedich-730	182	8	,	,	PUNCT
biomedich-730	182	9	a.	a.	PROPN
biomedich-730	182	10	k.	k.	PROPN
biomedich-730	182	11	(	(	PUNCT
biomedich-730	182	12	2013	2013	NUM
biomedich-730	182	13	)	)	PUNCT
biomedich-730	182	14	.	.	PUNCT
biomedich-730	183	1	chemistry	chemistry	NOUN
biomedich-730	183	2	and	and	CCONJ
biomedich-730	183	3	biological	biological	ADJ
biomedich-730	183	4	activities	activity	NOUN
biomedich-730	183	5	of	of	ADP
biomedich-730	183	6	flavonoids	flavonoid	NOUN
biomedich-730	183	7	:	:	PUNCT
biomedich-730	183	8	an	an	DET
biomedich-730	183	9	overview	overview	NOUN
biomedich-730	183	10	.	.	PUNCT
biomedich-730	184	1	thescientificworldjournal	thescientificworldjournal	ADJ
biomedich-730	184	2	,	,	PUNCT
biomedich-730	184	3	2013	2013	NUM
biomedich-730	184	4	,	,	PUNCT
biomedich-730	184	5	162750	162750	NUM
biomedich-730	184	6	.	.	PUNCT
biomedich-730	185	1	https://doi.org/10.1155/2013/162750	https://doi.org/10.1155/2013/162750	PROPN
biomedich-730	185	2	mariana	mariana	PROPN
biomedich-730	185	3	,	,	PUNCT
biomedich-730	185	4	m.	m.	NOUN
biomedich-730	185	5	,	,	PUNCT
biomedich-730	185	6	abbas	abbas	PROPN
biomedich-730	185	7	,	,	PUNCT
biomedich-730	185	8	s.	s.	PROPN
biomedich-730	185	9	,	,	PUNCT
biomedich-730	185	10	salamiah	salamiah	PROPN
biomedich-730	185	11	,	,	PUNCT
biomedich-730	185	12	s.	s.	PROPN
biomedich-730	185	13	,	,	PUNCT
biomedich-730	185	14	soedijo	soedijo	PROPN
biomedich-730	185	15	,	,	PUNCT
biomedich-730	185	16	s.	s.	PROPN
biomedich-730	185	17	,	,	PUNCT
biomedich-730	185	18	marsuni	marsuni	PROPN
biomedich-730	185	19	,	,	PUNCT
biomedich-730	185	20	y.	y.	PROPN
biomedich-730	185	21	,	,	PUNCT
biomedich-730	185	22	sepe	sepe	PROPN
biomedich-730	185	23	,	,	PUNCT
biomedich-730	185	24	m.	m.	NOUN
biomedich-730	185	25	,	,	PUNCT
biomedich-730	185	26	et	et	PROPN
biomedich-730	185	27	al	al	PROPN
biomedich-730	185	28	.	.	PROPN
biomedich-730	185	29	(	(	PUNCT
biomedich-730	185	30	2023	2023	NUM
biomedich-730	185	31	)	)	PUNCT
biomedich-730	185	32	.	.	PUNCT
biomedich-730	186	1	in	in	ADP
biomedich-730	186	2	silico	silico	NOUN
biomedich-730	186	3	analysis	analysis	NOUN
biomedich-730	186	4	of	of	ADP
biomedich-730	186	5	aspergillus	aspergillus	ADJ
biomedich-730	186	6	flavus	flavus	NOUN
biomedich-730	186	7	fungal	fungal	ADJ
biomedich-730	186	8	proteins	protein	NOUN
biomedich-730	186	9	:	:	PUNCT
biomedich-730	186	10	structural	structural	ADJ
biomedich-730	186	11	and	and	CCONJ
biomedich-730	186	12	functional	functional	ADJ
biomedich-730	186	13	insights	insight	NOUN
biomedich-730	186	14	using	use	VERB
biomedich-730	186	15	its	its	PRON
biomedich-730	186	16	primers	primer	NOUN
biomedich-730	186	17	.	.	PUNCT
biomedich-730	187	1	pakistan	pakistan	PROPN
biomedich-730	187	2	journal	journal	PROPN
biomedich-730	187	3	of	of	ADP
biomedich-730	187	4	phytopathology	phytopathology	NOUN
biomedich-730	187	5	.	.	PUNCT
biomedich-730	188	1	35(02):397	35(02):397	NUM
biomedich-730	188	2	-	-	SYM
biomedich-730	188	3	498	498	NUM
biomedich-730	188	4	.	.	PUNCT
biomedich-730	189	1	https://doi.org/10.33866/phytopathol.035.02.1037	https://doi.org/10.33866/phytopathol.035.02.1037	PROPN
biomedich-730	189	2	matsubara	matsubara	PROPN
biomedich-730	189	3	h.	h.	PROPN
biomedich-730	189	4	(	(	PUNCT
biomedich-730	189	5	1998	1998	NUM
biomedich-730	189	6	)	)	PUNCT
biomedich-730	189	7	.	.	PUNCT
biomedich-730	190	1	pathophysiological	pathophysiological	ADJ
biomedich-730	190	2	role	role	NOUN
biomedich-730	190	3	of	of	ADP
biomedich-730	190	4	angiotensin	angiotensin	PROPN
biomedich-730	190	5	ii	ii	PROPN
biomedich-730	190	6	type	type	NOUN
biomedich-730	190	7	2	2	NUM
biomedich-730	190	8	receptor	receptor	NOUN
biomedich-730	190	9	in	in	ADP
biomedich-730	190	10	cardiovascular	cardiovascular	ADJ
biomedich-730	190	11	and	and	CCONJ
biomedich-730	190	12	renal	renal	ADJ
biomedich-730	190	13	diseases	disease	NOUN
biomedich-730	190	14	.	.	PUNCT
biomedich-730	191	1	circulation	circulation	NOUN
biomedich-730	191	2	research	research	NOUN
biomedich-730	191	3	,	,	PUNCT
biomedich-730	191	4	83(12	83(12	NUM
biomedich-730	191	5	)	)	PUNCT
biomedich-730	191	6	,	,	PUNCT
biomedich-730	191	7	1182–1191	1182–1191	NUM
biomedich-730	191	8	.	.	PUNCT
biomedich-730	192	1	https://doi.org/10.1161/01.res.83.12.1182	https://doi.org/10.1161/01.res.83.12.1182	PROPN
biomedich-730	192	2	mierziak	mierziak	PROPN
biomedich-730	192	3	,	,	PUNCT
biomedich-730	192	4	j.	j.	PROPN
biomedich-730	192	5	,	,	PUNCT
biomedich-730	192	6	kostyn	kostyn	PROPN
biomedich-730	192	7	,	,	PUNCT
biomedich-730	192	8	k.	k.	PROPN
biomedich-730	192	9	,	,	PUNCT
biomedich-730	192	10	&	&	CCONJ
biomedich-730	192	11	kulma	kulma	PROPN
biomedich-730	192	12	,	,	PUNCT
biomedich-730	192	13	a.	a.	NOUN
biomedich-730	192	14	(	(	PUNCT
biomedich-730	192	15	2014	2014	NUM
biomedich-730	192	16	)	)	PUNCT
biomedich-730	192	17	.	.	PUNCT
biomedich-730	193	1	flavonoids	flavonoid	NOUN
biomedich-730	193	2	as	as	ADP
biomedich-730	193	3	important	important	ADJ
biomedich-730	193	4	molecules	molecule	NOUN
biomedich-730	193	5	of	of	ADP
biomedich-730	193	6	plant	plant	NOUN
biomedich-730	193	7	interactions	interaction	NOUN
biomedich-730	193	8	with	with	ADP
biomedich-730	193	9	the	the	DET
biomedich-730	193	10	environment	environment	NOUN
biomedich-730	193	11	.	.	PUNCT
biomedich-730	194	1	molecules	molecule	NOUN
biomedich-730	194	2	(	(	PUNCT
biomedich-730	194	3	basel	basel	PROPN
biomedich-730	194	4	,	,	PUNCT
biomedich-730	194	5	switzerland	switzerland	PROPN
biomedich-730	194	6	)	)	PUNCT
biomedich-730	194	7	,	,	PUNCT
biomedich-730	194	8	19(10	19(10	NUM
biomedich-730	194	9	)	)	PUNCT
biomedich-730	194	10	,	,	PUNCT
biomedich-730	194	11	16240	16240	NUM
biomedich-730	194	12	–	–	PUNCT
biomedich-730	194	13	16265	16265	NUM
biomedich-730	194	14	.	.	PUNCT
biomedich-730	195	1	https://doi.org/10.3390/molecules191016240	https://doi.org/10.3390/molecules191016240	PROPN
biomedich-730	195	2	miura	miura	PROPN
biomedich-730	195	3	,	,	PUNCT
biomedich-730	195	4	s.	s.	PROPN
biomedich-730	195	5	,	,	PUNCT
biomedich-730	195	6	karnik	karnik	PROPN
biomedich-730	195	7	,	,	PUNCT
biomedich-730	195	8	s.	s.	PROPN
biomedich-730	195	9	s.	s.	PROPN
biomedich-730	195	10	,	,	PUNCT
biomedich-730	195	11	&	&	CCONJ
biomedich-730	195	12	saku	saku	PROPN
biomedich-730	195	13	,	,	PUNCT
biomedich-730	195	14	k.	k.	PROPN
biomedich-730	195	15	(	(	PUNCT
biomedich-730	195	16	2011	2011	NUM
biomedich-730	195	17	)	)	PUNCT
biomedich-730	195	18	.	.	PUNCT
biomedich-730	196	1	review	review	NOUN
biomedich-730	196	2	:	:	PUNCT
biomedich-730	196	3	angiotensin	angiotensin	PROPN
biomedich-730	196	4	ii	ii	PROPN
biomedich-730	196	5	type	type	NOUN
biomedich-730	196	6	1	1	NUM
biomedich-730	196	7	receptor	receptor	NOUN
biomedich-730	196	8	blockers	blocker	NOUN
biomedich-730	196	9	:	:	PUNCT
biomedich-730	196	10	class	class	NOUN
biomedich-730	196	11	effects	effect	NOUN
biomedich-730	196	12	versus	versus	ADP
biomedich-730	196	13	molecular	molecular	ADJ
biomedich-730	196	14	effects	effect	NOUN
biomedich-730	196	15	.	.	PUNCT
biomedich-730	197	1	journal	journal	NOUN
biomedich-730	197	2	of	of	ADP
biomedich-730	197	3	the	the	DET
biomedich-730	197	4	renin	renin	ADJ
biomedich-730	197	5	-	-	PUNCT
biomedich-730	197	6	angiotensin	angiotensin	NOUN
biomedich-730	197	7	-	-	PUNCT
biomedich-730	197	8	aldosterone	aldosterone	NOUN
biomedich-730	197	9	system	system	NOUN
biomedich-730	197	10	:	:	PUNCT
biomedich-730	197	11	jraas	jraas	ADJ
biomedich-730	197	12	,	,	PUNCT
biomedich-730	197	13	12(1	12(1	NUM
biomedich-730	197	14	)	)	PUNCT
biomedich-730	197	15	,	,	PUNCT
biomedich-730	197	16	1–7	1–7	X
biomedich-730	197	17	.	.	PUNCT
biomedich-730	198	1	https://doi.org/10.1177/1470320310370852	https://doi.org/10.1177/1470320310370852	PRON
biomedich-730	198	2	mitkova	mitkova	NOUN
biomedich-730	198	3	,	,	PUNCT
biomedich-730	198	4	z.	z.	PROPN
biomedich-730	198	5	,	,	PUNCT
biomedich-730	198	6	dimova	dimova	PROPN
biomedich-730	198	7	,	,	PUNCT
biomedich-730	198	8	a.	a.	NOUN
biomedich-730	198	9	,	,	PUNCT
biomedich-730	198	10	petrova	petrova	PROPN
biomedich-730	198	11	,	,	PUNCT
biomedich-730	198	12	g.	g.	PROPN
biomedich-730	198	13	,	,	PUNCT
biomedich-730	198	14	&	&	CCONJ
biomedich-730	198	15	dimitrova	dimitrova	PROPN
biomedich-730	198	16	,	,	PUNCT
biomedich-730	198	17	m.	m.	NOUN
biomedich-730	198	18	(	(	PUNCT
biomedich-730	198	19	2024	2024	NUM
biomedich-730	198	20	)	)	PUNCT
biomedich-730	198	21	.	.	PUNCT
biomedich-730	199	1	adverse	adverse	ADJ
biomedich-730	199	2	drug	drug	NOUN
biomedich-730	199	3	reactions	reaction	NOUN
biomedich-730	199	4	of	of	ADP
biomedich-730	199	5	cardiovascular	cardiovascular	ADJ
biomedich-730	199	6	classes	class	NOUN
biomedich-730	199	7	of	of	ADP
biomedich-730	199	8	medicines	medicine	NOUN
biomedich-730	199	9	-	-	PUNCT
biomedich-730	199	10	data	datum	NOUN
biomedich-730	199	11	for	for	ADP
biomedich-730	199	12	bulgarian	bulgarian	ADJ
biomedich-730	199	13	population	population	NOUN
biomedich-730	199	14	.	.	PUNCT
biomedich-730	200	1	biomedicines	biomedicine	NOUN
biomedich-730	200	2	,	,	PUNCT
biomedich-730	200	3	12(10	12(10	NUM
biomedich-730	200	4	)	)	PUNCT
biomedich-730	200	5	,	,	PUNCT
biomedich-730	200	6	2163	2163	NUM
biomedich-730	200	7	.	.	PUNCT
biomedich-730	201	1	https://doi.org/10.3390/biomedicines12102163	https://doi.org/10.3390/biomedicines12102163	NOUN
biomedich-730	201	2	raddaoui	raddaoui	ADJ
biomedich-730	201	3	,	,	PUNCT
biomedich-730	201	4	y.	y.	PROPN
biomedich-730	201	5	,	,	PUNCT
biomedich-730	201	6	ben	ben	PROPN
biomedich-730	201	7	amara	amara	PROPN
biomedich-730	201	8	,	,	PUNCT
biomedich-730	201	9	a.	a.	NOUN
biomedich-730	201	10	,	,	PUNCT
biomedich-730	201	11	noamen	noaman	NOUN
biomedich-730	201	12	,	,	PUNCT
biomedich-730	201	13	a.	a.	NOUN
biomedich-730	201	14	,	,	PUNCT
biomedich-730	201	15	antit	antit	PROPN
biomedich-730	201	16	,	,	PUNCT
biomedich-730	201	17	s.	s.	PROPN
biomedich-730	201	18	,	,	PUNCT
biomedich-730	201	19	hajri	hajri	ADJ
biomedich-730	201	20	,	,	PUNCT
biomedich-730	201	21	y.	y.	PROPN
biomedich-730	201	22	,	,	PUNCT
biomedich-730	201	23	habli	habli	NOUN
biomedich-730	201	24	,	,	PUNCT
biomedich-730	201	25	j.	j.	PROPN
biomedich-730	201	26	,	,	PUNCT
biomedich-730	201	27	ibn	ibn	PROPN
biomedich-730	201	28	hadj	hadj	PROPN
biomedich-730	201	29	amor	amor	PROPN
biomedich-730	201	30	,	,	PUNCT
biomedich-730	201	31	h.	h.	PROPN
biomedich-730	201	32	,	,	PUNCT
biomedich-730	201	33	ben	ben	PROPN
biomedich-730	201	34	youssef	youssef	PROPN
biomedich-730	201	35	,	,	PUNCT
biomedich-730	201	36	y.	y.	PROPN
biomedich-730	201	37	,	,	PUNCT
biomedich-730	201	38	zakhama	zakhama	PROPN
biomedich-730	201	39	,	,	PUNCT
biomedich-730	201	40	l.	l.	PROPN
biomedich-730	201	41	,	,	PUNCT
biomedich-730	201	42	&	&	CCONJ
biomedich-730	201	43	fehri	fehri	PROPN
biomedich-730	201	44	,	,	PUNCT
biomedich-730	201	45	w.	w.	PROPN
biomedich-730	201	46	(	(	PUNCT
biomedich-730	201	47	2024	2024	NUM
biomedich-730	201	48	)	)	PUNCT
biomedich-730	201	49	.	.	PUNCT
biomedich-730	202	1	role	role	NOUN
biomedich-730	202	2	of	of	ADP
biomedich-730	202	3	depression	depression	NOUN
biomedich-730	202	4	in	in	ADP
biomedich-730	202	5	blood	blood	NOUN
biomedich-730	202	6	pressure	pressure	NOUN
biomedich-730	202	7	control	control	NOUN
biomedich-730	202	8	.	.	PUNCT
biomedich-730	203	1	a	a	DET
biomedich-730	203	2	cross	cross	ADJ
biomedich-730	203	3	-	-	ADJ
biomedich-730	203	4	sectional	sectional	ADJ
biomedich-730	203	5	multicentric	multicentric	ADJ
biomedich-730	203	6	study	study	NOUN
biomedich-730	203	7	.	.	PUNCT
biomedich-730	204	1	la	la	PROPN
biomedich-730	204	2	tunisie	tunisie	PROPN
biomedich-730	204	3	medicale	medicale	PROPN
biomedich-730	204	4	,	,	PUNCT
biomedich-730	204	5	102(1	102(1	NUM
biomedich-730	204	6	)	)	PUNCT
biomedich-730	204	7	,	,	PUNCT
biomedich-730	204	8	7–12	7–12	PROPN
biomedich-730	204	9	.	.	PUNCT
biomedich-730	205	1	https://doi.org/10.62438/tunismed.v102i1.4723	https://doi.org/10.62438/tunismed.v102i1.4723	PROPN
biomedich-730	205	2	prasanth	prasanth	NOUN
biomedich-730	205	3	,	,	PUNCT
biomedich-730	205	4	d.	d.	PROPN
biomedich-730	205	5	s.	s.	PROPN
biomedich-730	205	6	n.	n.	PROPN
biomedich-730	205	7	b.	b.	PROPN
biomedich-730	205	8	k.	k.	PROPN
biomedich-730	205	9	,	,	PUNCT
biomedich-730	205	10	murahari	murahari	PROPN
biomedich-730	205	11	,	,	PUNCT
biomedich-730	205	12	m.	m.	NOUN
biomedich-730	205	13	,	,	PUNCT
biomedich-730	205	14	chandramohan	chandramohan	PROPN
biomedich-730	205	15	,	,	PUNCT
biomedich-730	205	16	v.	v.	NOUN
biomedich-730	205	17	,	,	PUNCT
biomedich-730	205	18	panda	panda	NOUN
biomedich-730	205	19	,	,	PUNCT
biomedich-730	205	20	s.	s.	PROPN
biomedich-730	205	21	p.	p.	PROPN
biomedich-730	205	22	,	,	PUNCT
biomedich-730	205	23	atmakuri	atmakuri	PROPN
biomedich-730	205	24	,	,	PUNCT
biomedich-730	205	25	l.	l.	PROPN
biomedich-730	205	26	r.	r.	PROPN
biomedich-730	205	27	,	,	PUNCT
biomedich-730	205	28	&	&	CCONJ
biomedich-730	205	29	guntupalli	guntupalli	PROPN
biomedich-730	205	30	,	,	PUNCT
biomedich-730	205	31	c.	c.	NOUN
biomedich-730	205	32	(	(	PUNCT
biomedich-730	205	33	2021	2021	NUM
biomedich-730	205	34	)	)	PUNCT
biomedich-730	205	35	.	.	PUNCT
biomedich-730	206	1	in	in	ADP
biomedich-730	206	2	silico	silico	NOUN
biomedich-730	206	3	identification	identification	NOUN
biomedich-730	206	4	of	of	ADP
biomedich-730	206	5	potential	potential	ADJ
biomedich-730	206	6	inhibitors	inhibitor	NOUN
biomedich-730	206	7	from	from	ADP
biomedich-730	206	8	cinnamon	cinnamon	NOUN
biomedich-730	206	9	against	against	ADP
biomedich-730	206	10	main	main	ADJ
biomedich-730	206	11	protease	protease	NOUN
biomedich-730	206	12	and	and	CCONJ
biomedich-730	206	13	spike	spike	ADJ
biomedich-730	206	14	glycoprotein	glycoprotein	NOUN
biomedich-730	206	15	of	of	ADP
biomedich-730	206	16	sars	sars	PROPN
biomedich-730	206	17	cov-2	cov-2	PART
biomedich-730	206	18	.	.	PROPN
biomedich-730	206	19	journal	journal	PROPN
biomedich-730	206	20	of	of	ADP
biomedich-730	206	21	biomolecular	biomolecular	ADJ
biomedich-730	206	22	structure	structure	NOUN
biomedich-730	206	23	&	&	CCONJ
biomedich-730	206	24	dynamics	dynamic	NOUN
biomedich-730	206	25	,	,	PUNCT
biomedich-730	206	26	39(13	39(13	NUM
biomedich-730	206	27	)	)	PUNCT
biomedich-730	206	28	,	,	PUNCT
biomedich-730	206	29	4618	4618	NUM
biomedich-730	206	30	–	–	PUNCT
biomedich-730	206	31	4632	4632	NUM
biomedich-730	206	32	.	.	PUNCT
biomedich-730	207	1	https://doi.org/10.1080/07391102.2020.1779129	https://doi.org/10.1080/07391102.2020.1779129	PROPN
biomedich-730	207	2	https://doi.org/10.1038/s41598-023-40160-2	https://doi.org/10.1038/s41598-023-40160-2	PROPN
biomedich-730	208	1	https://doi.org/10.1186/s12879-024-09578-5	https://doi.org/10.1186/s12879-024-09578-5	NUM
biomedich-730	208	2	https://doi.org/10.1186/s12879-024-09578-5	https://doi.org/10.1186/s12879-024-09578-5	NUM
biomedich-730	209	1	https://doi.org/10.1097/hjh.0000000000003563	https://doi.org/10.1097/hjh.0000000000003563	PROPN
biomedich-730	209	2	https://doi.org/10.1161/hypertensionaha.120.16667	https://doi.org/10.1161/hypertensionaha.120.16667	PROPN
biomedich-730	209	3	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
biomedich-730	209	4	https://doi.org/10.1007/s12471-020-01439-5	https://doi.org/10.1007/s12471-020-01439-5	PROPN
biomedich-730	209	5	https://doi.org/10.6026/97320630011393	https://doi.org/10.6026/97320630011393	PROPN
biomedich-730	209	6	https://doi.org/10.1093/nar/gku293	https://doi.org/10.1093/nar/gku293	PROPN
biomedich-730	209	7	https://doi.org/10.1006/jmbi.1996.0633	https://doi.org/10.1006/jmbi.1996.0633	PROPN
biomedich-730	209	8	https://doi.org/10.21203/rs.3.rs-473901/v1	https://doi.org/10.21203/rs.3.rs-473901/v1	NOUN
biomedich-730	209	9	https://doi.org/10.21203/rs.3.rs-473901/v1	https://doi.org/10.21203/rs.3.rs-473901/v1	ADP
biomedich-730	209	10	https://doi.org/10.1038/ajh.2010.217	https://doi.org/10.1038/ajh.2010.217	NOUN
biomedich-730	210	1	https://doi.org/10.1371/journal.pone.0286349	https://doi.org/10.1371/journal.pone.0286349	PROPN
biomedich-730	210	2	https://doi.org/10.3390/molecules26165102	https://doi.org/10.3390/molecules26165102	PROPN
biomedich-730	210	3	https://doi.org/10.1155/2013/162750	https://doi.org/10.1155/2013/162750	PROPN
biomedich-730	210	4	https://doi.org/10.33866/phytopathol.035.02.1037	https://doi.org/10.33866/phytopathol.035.02.1037	PROPN
biomedich-730	210	5	https://doi.org/10.1161/01.res.83.12.1182	https://doi.org/10.1161/01.res.83.12.1182	PROPN
biomedich-730	210	6	https://doi.org/10.3390/molecules191016240	https://doi.org/10.3390/molecules191016240	PROPN
biomedich-730	210	7	https://doi.org/10.1177/1470320310370852	https://doi.org/10.1177/1470320310370852	X
biomedich-730	210	8	https://doi.org/10.3390/biomedicines12102163	https://doi.org/10.3390/biomedicines12102163	NOUN
biomedich-730	210	9	https://doi.org/10.62438/tunismed.v102i1.4723	https://doi.org/10.62438/tunismed.v102i1.4723	PROPN
biomedich-730	210	10	https://doi.org/10.1080/07391102.2020.1779129	https://doi.org/10.1080/07391102.2020.1779129	PROPN
biomedich-730	210	11	282	282	NUM
biomedich-730	210	12	biology	biology	NOUN
biomedich-730	210	13	,	,	PUNCT
biomedich-730	210	14	medicine	medicine	NOUN
biomedich-730	210	15	,	,	PUNCT
biomedich-730	210	16	&	&	CCONJ
biomedich-730	210	17	natural	natural	ADJ
biomedich-730	210	18	product	product	NOUN
biomedich-730	210	19	chemistry	chemistry	NOUN
biomedich-730	210	20	14	14	NUM
biomedich-730	210	21	(	(	PUNCT
biomedich-730	210	22	1	1	NUM
biomedich-730	210	23	)	)	PUNCT
biomedich-730	210	24	,	,	PUNCT
biomedich-730	210	25	2025	2025	NUM
biomedich-730	210	26	:	:	PUNCT
biomedich-730	210	27	275	275	NUM
biomedich-730	210	28	-	-	SYM
biomedich-730	210	29	282	282	NUM
biomedich-730	210	30	putra	putra	PROPN
biomedich-730	210	31	,	,	PUNCT
biomedich-730	210	32	w.	w.	PROPN
biomedich-730	210	33	e.	e.	PROPN
biomedich-730	210	34	,	,	PUNCT
biomedich-730	210	35	sustiprijatno	sustiprijatno	PROPN
biomedich-730	210	36	,	,	PUNCT
biomedich-730	210	37	arief	arief	NOUN
biomedich-730	210	38	,	,	PUNCT
biomedich-730	210	39	h.	h.	PROPN
biomedich-730	210	40	,	,	PUNCT
biomedich-730	210	41	widiastuti	widiastuti	PROPN
biomedich-730	210	42	,	,	PUNCT
biomedich-730	210	43	d.	d.	PROPN
biomedich-730	210	44	,	,	PUNCT
biomedich-730	210	45	heikal	heikal	NOUN
biomedich-730	210	46	,	,	PUNCT
biomedich-730	210	47	m.	m.	PROPN
biomedich-730	210	48	f.	f.	PROPN
biomedich-730	210	49	(	(	PUNCT
biomedich-730	210	50	2024	2024	NUM
biomedich-730	210	51	)	)	PUNCT
biomedich-730	210	52	.	.	PUNCT
biomedich-730	211	1	computational	computational	ADJ
biomedich-730	211	2	screening	screening	NOUN
biomedich-730	211	3	of	of	ADP
biomedich-730	211	4	rheum	rheum	NOUN
biomedich-730	211	5	palmatum	palmatum	NOUN
biomedich-730	211	6	phytochemicals	phytochemical	NOUN
biomedich-730	211	7	as	as	ADP
biomedich-730	211	8	potential	potential	ADJ
biomedich-730	211	9	antidiabetes	antidiabete	VERB
biomedich-730	211	10	agent	agent	NOUN
biomedich-730	211	11	via	via	ADP
biomedich-730	211	12	sodiumglucose	sodiumglucose	NOUN
biomedich-730	211	13	transport	transport	NOUN
biomedich-730	211	14	protein	protein	NOUN
biomedich-730	211	15	2	2	NUM
biomedich-730	211	16	inhibition	inhibition	NOUN
biomedich-730	211	17	.	.	PUNCT
biomedich-730	212	1	science	science	PROPN
biomedich-730	212	2	&	&	CCONJ
biomedich-730	212	3	technology	technology	PROPN
biomedich-730	212	4	asia	asia	PROPN
biomedich-730	212	5	.	.	PUNCT
biomedich-730	213	1	29(03):256	29(03):256	PROPN
biomedich-730	213	2	-	-	SYM
biomedich-730	213	3	268	268	NUM
biomedich-730	213	4	.	.	PUNCT
biomedich-730	214	1	shaito	shaito	NOUN
biomedich-730	214	2	,	,	PUNCT
biomedich-730	214	3	a.	a.	PROPN
biomedich-730	214	4	,	,	PUNCT
biomedich-730	214	5	thuan	thuan	PROPN
biomedich-730	214	6	,	,	PUNCT
biomedich-730	214	7	d.	d.	PROPN
biomedich-730	214	8	t.	t.	PROPN
biomedich-730	214	9	b.	b.	PROPN
biomedich-730	214	10	,	,	PUNCT
biomedich-730	214	11	phu	phu	PROPN
biomedich-730	214	12	,	,	PUNCT
biomedich-730	214	13	h.	h.	PROPN
biomedich-730	214	14	t.	t.	PROPN
biomedich-730	214	15	,	,	PUNCT
biomedich-730	214	16	nguyen	nguyen	NOUN
biomedich-730	214	17	,	,	PUNCT
biomedich-730	214	18	t.	t.	PROPN
biomedich-730	214	19	h.	h.	PROPN
biomedich-730	214	20	d.	d.	PROPN
biomedich-730	214	21	,	,	PUNCT
biomedich-730	214	22	hasan	hasan	PROPN
biomedich-730	214	23	,	,	PUNCT
biomedich-730	214	24	h.	h.	PROPN
biomedich-730	214	25	,	,	PUNCT
biomedich-730	214	26	halabi	halabi	INTJ
biomedich-730	214	27	,	,	PUNCT
biomedich-730	214	28	s.	s.	PROPN
biomedich-730	214	29	,	,	PUNCT
biomedich-730	214	30	abdelhady	abdelhady	ADJ
biomedich-730	214	31	,	,	PUNCT
biomedich-730	214	32	s.	s.	PROPN
biomedich-730	214	33	,	,	PUNCT
biomedich-730	214	34	nasrallah	nasrallah	PROPN
biomedich-730	214	35	,	,	PUNCT
biomedich-730	214	36	g.	g.	PROPN
biomedich-730	214	37	k.	k.	PROPN
biomedich-730	214	38	,	,	PUNCT
biomedich-730	214	39	eid	eid	PROPN
biomedich-730	214	40	,	,	PUNCT
biomedich-730	214	41	a.	a.	PROPN
biomedich-730	214	42	h.	h.	PROPN
biomedich-730	214	43	,	,	PUNCT
biomedich-730	214	44	&	&	CCONJ
biomedich-730	214	45	pintus	pintus	PROPN
biomedich-730	214	46	,	,	PUNCT
biomedich-730	214	47	g.	g.	PROPN
biomedich-730	214	48	(	(	PUNCT
biomedich-730	214	49	2020	2020	NUM
biomedich-730	214	50	)	)	PUNCT
biomedich-730	214	51	.	.	PUNCT
biomedich-730	215	1	herbal	herbal	ADJ
biomedich-730	215	2	medicine	medicine	NOUN
biomedich-730	215	3	for	for	ADP
biomedich-730	215	4	cardiovascular	cardiovascular	ADJ
biomedich-730	215	5	diseases	disease	NOUN
biomedich-730	215	6	:	:	PUNCT
biomedich-730	215	7	efficacy	efficacy	NOUN
biomedich-730	215	8	,	,	PUNCT
biomedich-730	215	9	mechanisms	mechanism	NOUN
biomedich-730	215	10	,	,	PUNCT
biomedich-730	215	11	and	and	CCONJ
biomedich-730	215	12	safety	safety	NOUN
biomedich-730	215	13	.	.	PUNCT
biomedich-730	216	1	frontiers	frontier	NOUN
biomedich-730	216	2	in	in	ADP
biomedich-730	216	3	pharmacology	pharmacology	NOUN
biomedich-730	216	4	,	,	PUNCT
biomedich-730	216	5	11	11	NUM
biomedich-730	216	6	,	,	PUNCT
biomedich-730	216	7	422	422	NUM
biomedich-730	216	8	.	.	PUNCT
biomedich-730	217	1	https://doi.org/10.3389/fphar.2020.00422	https://doi.org/10.3389/fphar.2020.00422	PROPN
biomedich-730	217	2	sri	sri	PROPN
biomedich-730	217	3	prakash	prakash	PROPN
biomedich-730	217	4	,	,	PUNCT
biomedich-730	217	5	s.	s.	PROPN
biomedich-730	217	6	r.	r.	PROPN
biomedich-730	217	7	,	,	PUNCT
biomedich-730	217	8	kamalnath	kamalnath	PROPN
biomedich-730	217	9	,	,	PUNCT
biomedich-730	217	10	s.	s.	PROPN
biomedich-730	217	11	m.	m.	PROPN
biomedich-730	217	12	,	,	PUNCT
biomedich-730	217	13	antonisamy	antonisamy	PROPN
biomedich-730	217	14	,	,	PUNCT
biomedich-730	217	15	a.	a.	PROPN
biomedich-730	217	16	j.	j.	PROPN
biomedich-730	217	17	,	,	PUNCT
biomedich-730	217	18	marimuthu	marimuthu	PROPN
biomedich-730	217	19	,	,	PUNCT
biomedich-730	217	20	s.	s.	PROPN
biomedich-730	217	21	,	,	PUNCT
biomedich-730	217	22	&	&	CCONJ
biomedich-730	217	23	malayandi	malayandi	PROPN
biomedich-730	217	24	,	,	PUNCT
biomedich-730	217	25	s.	s.	PROPN
biomedich-730	217	26	(	(	PUNCT
biomedich-730	217	27	2023	2023	NUM
biomedich-730	217	28	)	)	PUNCT
biomedich-730	217	29	.	.	PUNCT
biomedich-730	218	1	in	in	ADP
biomedich-730	218	2	silico	silico	NOUN
biomedich-730	218	3	molecular	molecular	ADJ
biomedich-730	218	4	docking	docking	NOUN
biomedich-730	218	5	of	of	ADP
biomedich-730	218	6	phytochemicals	phytochemical	NOUN
biomedich-730	218	7	for	for	ADP
biomedich-730	218	8	type	type	NOUN
biomedich-730	218	9	2	2	NUM
biomedich-730	218	10	diabetes	diabetes	NOUN
biomedich-730	218	11	mellitus	mellitus	NOUN
biomedich-730	218	12	therapy	therapy	NOUN
biomedich-730	218	13	:	:	PUNCT
biomedich-730	218	14	a	a	DET
biomedich-730	218	15	network	network	NOUN
biomedich-730	218	16	pharmacology	pharmacology	NOUN
biomedich-730	218	17	approach	approach	NOUN
biomedich-730	218	18	.	.	PUNCT
biomedich-730	219	1	international	international	ADJ
biomedich-730	219	2	journal	journal	NOUN
biomedich-730	219	3	of	of	ADP
biomedich-730	219	4	molecular	molecular	ADJ
biomedich-730	219	5	and	and	CCONJ
biomedich-730	219	6	cellular	cellular	ADJ
biomedich-730	219	7	medicine	medicine	NOUN
biomedich-730	219	8	,	,	PUNCT
biomedich-730	219	9	12(4	12(4	NUM
biomedich-730	219	10	)	)	PUNCT
biomedich-730	219	11	,	,	PUNCT
biomedich-730	219	12	372–387	372–387	NUM
biomedich-730	219	13	.	.	PUNCT
biomedich-730	220	1	https://doi.org/10.22088/ijmcm.bums.12.4.372	https://doi.org/10.22088/ijmcm.bums.12.4.372	PROPN
biomedich-730	220	2	sumitha	sumitha	PROPN
biomedich-730	220	3	,	,	PUNCT
biomedich-730	220	4	a.	a.	NOUN
biomedich-730	220	5	,	,	PUNCT
biomedich-730	220	6	devi	devi	PROPN
biomedich-730	220	7	,	,	PUNCT
biomedich-730	220	8	p.	p.	PROPN
biomedich-730	220	9	b.	b.	PROPN
biomedich-730	220	10	,	,	PUNCT
biomedich-730	220	11	hari	hari	PROPN
biomedich-730	220	12	,	,	PUNCT
biomedich-730	220	13	s.	s.	PROPN
biomedich-730	220	14	,	,	PUNCT
biomedich-730	220	15	&	&	CCONJ
biomedich-730	220	16	dhanasekaran	dhanasekaran	PROPN
biomedich-730	220	17	,	,	PUNCT
biomedich-730	220	18	r.	r.	PROPN
biomedich-730	220	19	(	(	PUNCT
biomedich-730	220	20	2020	2020	NUM
biomedich-730	220	21	)	)	PUNCT
biomedich-730	220	22	.	.	PUNCT
biomedich-730	221	1	covid-19	covid-19	PROPN
biomedich-730	221	2	—	—	PUNCT
biomedich-730	221	3	in	in	ADP
biomedich-730	221	4	silico	silico	NOUN
biomedich-730	221	5	structure	structure	NOUN
biomedich-730	221	6	prediction	prediction	NOUN
biomedich-730	221	7	and	and	CCONJ
biomedich-730	221	8	molecular	molecular	ADJ
biomedich-730	221	9	docking	docking	NOUN
biomedich-730	221	10	studies	study	NOUN
biomedich-730	221	11	with	with	ADP
biomedich-730	221	12	doxycycline	doxycycline	NOUN
biomedich-730	221	13	and	and	CCONJ
biomedich-730	221	14	quinine	quinine	NOUN
biomedich-730	221	15	.	.	PUNCT
biomedich-730	222	1	biomedicine	biomedicine	NOUN
biomedich-730	222	2	and	and	CCONJ
biomedich-730	222	3	pharmacology	pharmacology	NOUN
biomedich-730	222	4	journal	journal	NOUN
biomedich-730	222	5	,	,	PUNCT
biomedich-730	222	6	13(3	13(3	NUM
biomedich-730	222	7	)	)	PUNCT
biomedich-730	222	8	.	.	PUNCT
biomedich-730	223	1	https://dx.doi.org/10.13005/bpj/1986	https://dx.doi.org/10.13005/bpj/1986	PROPN
biomedich-730	223	2	tithi	tithi	PROPN
biomedich-730	223	3	,	,	PUNCT
biomedich-730	223	4	t.	t.	PROPN
biomedich-730	223	5	i.	i.	PROPN
biomedich-730	223	6	,	,	PUNCT
biomedich-730	223	7	tahsin	tahsin	PROPN
biomedich-730	223	8	,	,	PUNCT
biomedich-730	223	9	m.	m.	PROPN
biomedich-730	223	10	r.	r.	PROPN
biomedich-730	223	11	,	,	PUNCT
biomedich-730	223	12	anjum	anjum	PROPN
biomedich-730	223	13	,	,	PUNCT
biomedich-730	223	14	j.	j.	PROPN
biomedich-730	223	15	,	,	PUNCT
biomedich-730	223	16	zaman	zaman	PROPN
biomedich-730	223	17	,	,	PUNCT
biomedich-730	223	18	t.	t.	PROPN
biomedich-730	223	19	s.	s.	PROPN
biomedich-730	223	20	,	,	PUNCT
biomedich-730	223	21	aktar	aktar	PROPN
biomedich-730	223	22	,	,	PUNCT
biomedich-730	223	23	f.	f.	PROPN
biomedich-730	223	24	,	,	PUNCT
biomedich-730	223	25	bahar	bahar	PROPN
biomedich-730	223	26	,	,	PUNCT
biomedich-730	223	27	n.	n.	PROPN
biomedich-730	223	28	b.	b.	PROPN
biomedich-730	223	29	,	,	PUNCT
biomedich-730	223	30	tasnim	tasnim	NOUN
biomedich-730	223	31	,	,	PUNCT
biomedich-730	223	32	s.	s.	PROPN
biomedich-730	223	33	,	,	PUNCT
biomedich-730	223	34	sultana	sultana	PROPN
biomedich-730	223	35	,	,	PUNCT
biomedich-730	223	36	a.	a.	PROPN
biomedich-730	223	37	,	,	PUNCT
biomedich-730	223	38	jahan	jahan	PROPN
biomedich-730	223	39	,	,	PUNCT
biomedich-730	223	40	i.	i.	PROPN
biomedich-730	223	41	,	,	PUNCT
biomedich-730	223	42	afrin	afrin	PROPN
biomedich-730	223	43	,	,	PUNCT
biomedich-730	223	44	s.	s.	PROPN
biomedich-730	223	45	s.	s.	PROPN
biomedich-730	223	46	,	,	PUNCT
biomedich-730	223	47	akter	akter	NOUN
biomedich-730	223	48	,	,	PUNCT
biomedich-730	223	49	t.	t.	PROPN
biomedich-730	223	50	,	,	PUNCT
biomedich-730	223	51	sen	sen	PROPN
biomedich-730	223	52	,	,	PUNCT
biomedich-730	223	53	p.	p.	NOUN
biomedich-730	223	54	,	,	PUNCT
biomedich-730	223	55	koly	koly	PROPN
biomedich-730	223	56	,	,	PUNCT
biomedich-730	223	57	f.	f.	PROPN
biomedich-730	223	58	j.	j.	PROPN
biomedich-730	223	59	,	,	PUNCT
biomedich-730	223	60	reza	reza	PROPN
biomedich-730	223	61	,	,	PUNCT
biomedich-730	223	62	m.	m.	NOUN
biomedich-730	223	63	s.	s.	PROPN
biomedich-730	223	64	,	,	PUNCT
biomedich-730	223	65	chowdhury	chowdhury	PROPN
biomedich-730	223	66	,	,	PUNCT
biomedich-730	223	67	j.	j.	PROPN
biomedich-730	223	68	a.	a.	PROPN
biomedich-730	223	69	,	,	PUNCT
biomedich-730	223	70	kabir	kabir	PROPN
biomedich-730	223	71	,	,	PUNCT
biomedich-730	223	72	s.	s.	PROPN
biomedich-730	223	73	,	,	PUNCT
biomedich-730	223	74	chowdhury	chowdhury	PROPN
biomedich-730	223	75	,	,	PUNCT
biomedich-730	223	76	a.	a.	NOUN
biomedich-730	223	77	a.	a.	PROPN
biomedich-730	223	78	,	,	PUNCT
biomedich-730	223	79	&	&	CCONJ
biomedich-730	223	80	amran	amran	PROPN
biomedich-730	223	81	,	,	PUNCT
biomedich-730	223	82	m.	m.	NOUN
biomedich-730	223	83	s.	s.	PROPN
biomedich-730	223	84	(	(	PUNCT
biomedich-730	223	85	2023	2023	NUM
biomedich-730	223	86	)	)	PUNCT
biomedich-730	223	87	.	.	PUNCT
biomedich-730	224	1	an	an	DET
biomedich-730	224	2	in	in	ADP
biomedich-730	224	3	vivo	vivo	NOUN
biomedich-730	224	4	and	and	CCONJ
biomedich-730	224	5	in	in	ADP
biomedich-730	224	6	silico	silico	NOUN
biomedich-730	224	7	evaluation	evaluation	NOUN
biomedich-730	224	8	of	of	ADP
biomedich-730	224	9	the	the	DET
biomedich-730	224	10	hepatoprotective	hepatoprotective	ADJ
biomedich-730	224	11	potential	potential	NOUN
biomedich-730	224	12	of	of	ADP
biomedich-730	224	13	gynura	gynura	NOUN
biomedich-730	224	14	procumbens	procumben	NOUN
biomedich-730	224	15	:	:	PUNCT
biomedich-730	224	16	a	a	DET
biomedich-730	224	17	promising	promising	ADJ
biomedich-730	224	18	agent	agent	NOUN
biomedich-730	224	19	for	for	ADP
biomedich-730	224	20	combating	combat	VERB
biomedich-730	224	21	hepatotoxicity	hepatotoxicity	NOUN
biomedich-730	224	22	.	.	PUNCT
biomedich-730	225	1	plos	plos	PROPN
biomedich-730	225	2	one	one	NUM
biomedich-730	225	3	,	,	PUNCT
biomedich-730	225	4	18(9	18(9	NOUN
biomedich-730	225	5	)	)	PUNCT
biomedich-730	225	6	,	,	PUNCT
biomedich-730	225	7	e0291125	e0291125	PROPN
biomedich-730	225	8	.	.	PUNCT
biomedich-730	226	1	https://doi.org/10.1371/journal.pone.0291125	https://doi.org/10.1371/journal.pone.0291125	PROPN
biomedich-730	226	2	uma	uma	PROPN
biomedich-730	226	3	maheswari	maheswari	PROPN
biomedich-730	226	4	,	,	PUNCT
biomedich-730	226	5	k.	k.	PROPN
biomedich-730	226	6	,	,	PUNCT
biomedich-730	226	7	&	&	CCONJ
biomedich-730	226	8	sankar	sankar	PROPN
biomedich-730	226	9	,	,	PUNCT
biomedich-730	226	10	s.	s.	PROPN
biomedich-730	226	11	(	(	PUNCT
biomedich-730	226	12	2024	2024	NUM
biomedich-730	226	13	)	)	PUNCT
biomedich-730	226	14	.	.	PUNCT
biomedich-730	227	1	in	in	ADP
biomedich-730	227	2	silico	silico	NOUN
biomedich-730	227	3	molecular	molecular	ADJ
biomedich-730	227	4	docking	docking	NOUN
biomedich-730	227	5	of	of	ADP
biomedich-730	227	6	phytochemicals	phytochemical	NOUN
biomedich-730	227	7	of	of	ADP
biomedich-730	227	8	murraya	murraya	NOUN
biomedich-730	227	9	koenigii	koenigii	NOUN
biomedich-730	227	10	against	against	ADP
biomedich-730	227	11	streptococcus	streptococcus	NOUN
biomedich-730	227	12	mutans	mutan	NOUN
biomedich-730	227	13	.	.	PUNCT
biomedich-730	228	1	cureus	cureus	NOUN
biomedich-730	228	2	,	,	PUNCT
biomedich-730	228	3	16(2	16(2	NUM
biomedich-730	228	4	)	)	PUNCT
biomedich-730	228	5	,	,	PUNCT
biomedich-730	228	6	e53679	e53679	PROPN
biomedich-730	228	7	.	.	PUNCT
biomedich-730	228	8	https://doi.org/10.7759/cureus.53679	https://doi.org/10.7759/cureus.53679	PROPN
biomedich-730	228	9	vardhan	vardhan	PROPN
biomedich-730	228	10	,	,	PUNCT
biomedich-730	228	11	s.	s.	PROPN
biomedich-730	228	12	,	,	PUNCT
biomedich-730	228	13	&	&	CCONJ
biomedich-730	228	14	sahoo	sahoo	PROPN
biomedich-730	228	15	,	,	PUNCT
biomedich-730	228	16	s.	s.	PROPN
biomedich-730	228	17	k.	k.	PROPN
biomedich-730	228	18	(	(	PUNCT
biomedich-730	228	19	2020	2020	NUM
biomedich-730	228	20	)	)	PUNCT
biomedich-730	228	21	.	.	PUNCT
biomedich-730	229	1	in	in	ADP
biomedich-730	229	2	silico	silico	NOUN
biomedich-730	229	3	admet	admet	NOUN
biomedich-730	229	4	and	and	CCONJ
biomedich-730	229	5	molecular	molecular	ADJ
biomedich-730	229	6	docking	docking	NOUN
biomedich-730	229	7	study	study	NOUN
biomedich-730	229	8	on	on	ADP
biomedich-730	229	9	searching	search	VERB
biomedich-730	229	10	potential	potential	ADJ
biomedich-730	229	11	inhibitors	inhibitor	NOUN
biomedich-730	229	12	from	from	ADP
biomedich-730	229	13	limonoids	limonoid	NOUN
biomedich-730	229	14	and	and	CCONJ
biomedich-730	229	15	triterpenoids	triterpenoid	NOUN
biomedich-730	229	16	for	for	ADP
biomedich-730	229	17	covid-19	covid-19	PROPN
biomedich-730	229	18	.	.	PUNCT
biomedich-730	229	19	computers	computer	NOUN
biomedich-730	229	20	in	in	ADP
biomedich-730	229	21	biology	biology	NOUN
biomedich-730	229	22	and	and	CCONJ
biomedich-730	229	23	medicine	medicine	NOUN
biomedich-730	229	24	,	,	PUNCT
biomedich-730	229	25	124	124	NUM
biomedich-730	229	26	,	,	PUNCT
biomedich-730	229	27	103936	103936	NUM
biomedich-730	229	28	.	.	PUNCT
biomedich-730	230	1	https://doi.org/10.1016/j.compbiomed.2020.103936	https://doi.org/10.1016/j.compbiomed.2020.103936	PROPN
biomedich-730	230	2	ysrafil	ysrafil	PROPN
biomedich-730	230	3	,	,	PUNCT
biomedich-730	230	4	y.	y.	PROPN
biomedich-730	230	5	,	,	PUNCT
biomedich-730	230	6	sapiun	sapiun	PROPN
biomedich-730	230	7	,	,	PUNCT
biomedich-730	230	8	z.	z.	PROPN
biomedich-730	230	9	,	,	PUNCT
biomedich-730	230	10	slamet	slamet	PROPN
biomedich-730	230	11	,	,	PUNCT
biomedich-730	230	12	n.	n.	PROPN
biomedich-730	230	13	s.	s.	PROPN
biomedich-730	230	14	,	,	PUNCT
biomedich-730	230	15	mohamad	mohamad	PROPN
biomedich-730	230	16	,	,	PUNCT
biomedich-730	230	17	f.	f.	PROPN
biomedich-730	230	18	,	,	PUNCT
biomedich-730	230	19	hartati	hartati	PROPN
biomedich-730	230	20	,	,	PUNCT
biomedich-730	230	21	h.	h.	PROPN
biomedich-730	230	22	,	,	PUNCT
biomedich-730	230	23	damiti	damiti	PROPN
biomedich-730	230	24	,	,	PUNCT
biomedich-730	230	25	s.	s.	PROPN
biomedich-730	230	26	a.	a.	PROPN
biomedich-730	230	27	,	,	PUNCT
biomedich-730	230	28	alexandra	alexandra	PROPN
biomedich-730	230	29	,	,	PUNCT
biomedich-730	230	30	f.	f.	PROPN
biomedich-730	230	31	d.	d.	PROPN
biomedich-730	230	32	,	,	PUNCT
biomedich-730	230	33	rahman	rahman	PROPN
biomedich-730	230	34	,	,	PUNCT
biomedich-730	230	35	s.	s.	PROPN
biomedich-730	230	36	,	,	PUNCT
biomedich-730	230	37	masyeni	masyeni	PROPN
biomedich-730	230	38	,	,	PUNCT
biomedich-730	230	39	s.	s.	PROPN
biomedich-730	230	40	,	,	PUNCT
biomedich-730	230	41	harapan	harapan	PROPN
biomedich-730	230	42	,	,	PUNCT
biomedich-730	230	43	h.	h.	PROPN
biomedich-730	230	44	,	,	PUNCT
biomedich-730	230	45	mamada	mamada	PROPN
biomedich-730	230	46	,	,	PUNCT
biomedich-730	230	47	s.	s.	PROPN
biomedich-730	230	48	s.	s.	PROPN
biomedich-730	230	49	,	,	PUNCT
biomedich-730	230	50	bin	bin	PROPN
biomedich-730	230	51	emran	emran	NOUN
biomedich-730	230	52	,	,	PUNCT
biomedich-730	230	53	t.	t.	PROPN
biomedich-730	230	54	,	,	PUNCT
biomedich-730	230	55	&	&	CCONJ
biomedich-730	230	56	nainu	nainu	PROPN
biomedich-730	230	57	,	,	PUNCT
biomedich-730	230	58	f.	f.	PROPN
biomedich-730	230	59	(	(	PUNCT
biomedich-730	230	60	2023	2023	NUM
biomedich-730	230	61	)	)	PUNCT
biomedich-730	230	62	.	.	PUNCT
biomedich-730	231	1	anti	anti	ADJ
biomedich-730	231	2	-	-	ADJ
biomedich-730	231	3	inflammatory	inflammatory	ADJ
biomedich-730	231	4	activities	activity	NOUN
biomedich-730	231	5	of	of	ADP
biomedich-730	231	6	flavonoid	flavonoid	NOUN
biomedich-730	231	7	derivates	derivate	NOUN
biomedich-730	231	8	.	.	PUNCT
biomedich-730	232	1	admet	admet	PROPN
biomedich-730	232	2	&	&	CCONJ
biomedich-730	232	3	dmpk	dmpk	PROPN
biomedich-730	232	4	,	,	PUNCT
biomedich-730	232	5	11(3	11(3	NUM
biomedich-730	232	6	)	)	PUNCT
biomedich-730	232	7	,	,	PUNCT
biomedich-730	232	8	331–359	331–359	NUM
biomedich-730	232	9	.	.	PUNCT
biomedich-730	233	1	https://doi.org/10.5599/admet.1918	https://doi.org/10.5599/admet.1918	NOUN
biomedich-730	233	2	https://doi.org/10.3389/fphar.2020.00422	https://doi.org/10.3389/fphar.2020.00422	PRON
biomedich-730	233	3	https://doi.org/10.22088/ijmcm.bums.12.4.372	https://doi.org/10.22088/ijmcm.bums.12.4.372	VERB
biomedich-730	233	4	https://dx.doi.org/10.13005/bpj/1986	https://dx.doi.org/10.13005/bpj/1986	PROPN
biomedich-730	233	5	https://doi.org/10.1371/journal.pone.0291125	https://doi.org/10.1371/journal.pone.0291125	PROPN
biomedich-730	233	6	https://doi.org/10.7759/cureus.53679	https://doi.org/10.7759/cureus.53679	PROPN
biomedich-730	233	7	https://doi.org/10.1016/j.compbiomed.2020.103936	https://doi.org/10.1016/j.compbiomed.2020.103936	PROPN
biomedich-730	233	8	https://doi.org/10.5599/admet.1918	https://doi.org/10.5599/admet.1918	NOUN