id	sid	tid	token	lemma	pos
biomedich-739	1	1	biology	biology	NOUN
biomedich-739	1	2	,	,	PUNCT
biomedich-739	1	3	medicine	medicine	NOUN
biomedich-739	1	4	,	,	PUNCT
biomedich-739	1	5	&	&	CCONJ
biomedich-739	1	6	natural	natural	ADJ
biomedich-739	1	7	product	product	NOUN
biomedich-739	1	8	chemistry	chemistry	NOUN
biomedich-739	1	9	issn	issn	VERB
biomedich-739	1	10	2089	2089	NUM
biomedich-739	1	11	-	-	SYM
biomedich-739	1	12	6514	6514	NUM
biomedich-739	1	13	(	(	PUNCT
biomedich-739	1	14	paper	paper	NOUN
biomedich-739	1	15	)	)	PUNCT
biomedich-739	1	16	volume	volume	NOUN
biomedich-739	1	17	14	14	NUM
biomedich-739	1	18	,	,	PUNCT
biomedich-739	1	19	number	number	NOUN
biomedich-739	1	20	1	1	NUM
biomedich-739	1	21	,	,	PUNCT
biomedich-739	1	22	april	april	PROPN
biomedich-739	1	23	2025	2025	NUM
biomedich-739	1	24	|	|	ADV
biomedich-739	1	25	pages	page	NOUN
biomedich-739	1	26	:	:	PUNCT
biomedich-739	1	27	357	357	NUM
biomedich-739	1	28	-	-	SYM
biomedich-739	1	29	361	361	NUM
biomedich-739	1	30	|	|	ADV
biomedich-739	1	31	doi	doi	NOUN
biomedich-739	1	32	:	:	PUNCT
biomedich-739	1	33	10.14421	10.14421	NUM
biomedich-739	1	34	/	/	SYM
biomedich-739	1	35	biomedich.2025.141.357	biomedich.2025.141.357	NOUN
biomedich-739	1	36	-	-	PUNCT
biomedich-739	1	37	361	361	NUM
biomedich-739	1	38	issn	issn	PROPN
biomedich-739	1	39	2540	2540	NUM
biomedich-739	1	40	-	-	SYM
biomedich-739	1	41	9328	9328	NUM
biomedich-739	1	42	(	(	PUNCT
biomedich-739	1	43	online	online	ADJ
biomedich-739	1	44	)	)	PUNCT
biomedich-739	1	45	potential	potential	ADJ
biomedich-739	1	46	effect	effect	NOUN
biomedich-739	1	47	of	of	ADP
biomedich-739	1	48	orthosiphon	orthosiphon	ADJ
biomedich-739	1	49	aristatus	aristatus	NOUN
biomedich-739	1	50	leaf	leaf	NOUN
biomedich-739	1	51	extract	extract	NOUN
biomedich-739	1	52	in	in	ADP
biomedich-739	1	53	improving	improve	VERB
biomedich-739	1	54	collagen	collagen	NOUN
biomedich-739	1	55	1	1	NUM
biomedich-739	1	56	alpha	alpha	NOUN
biomedich-739	1	57	1	1	NUM
biomedich-739	1	58	expression	expression	NOUN
biomedich-739	1	59	in	in	ADP
biomedich-739	1	60	hyperglycemia	hyperglycemia	NOUN
biomedich-739	1	61	-	-	PUNCT
biomedich-739	1	62	induced	induce	VERB
biomedich-739	1	63	rats	rat	NOUN
biomedich-739	1	64	riandini	riandini	NOUN
biomedich-739	1	65	aisyah1	aisyah1	PROPN
biomedich-739	1	66	,	,	PUNCT
biomedich-739	1	67	*	*	PROPN
biomedich-739	1	68	,	,	PUNCT
biomedich-739	1	69	erika	erika	PROPN
biomedich-739	1	70	diana	diana	PROPN
biomedich-739	1	71	risanti1	risanti1	PROPN
biomedich-739	1	72	,	,	PUNCT
biomedich-739	1	73	safari	safari	ADJ
biomedich-739	1	74	wahyu	wahyu	NOUN
biomedich-739	1	75	jatmiko1	jatmiko1	PROPN
biomedich-739	1	76	,	,	PUNCT
biomedich-739	1	77	fatin	fatin	NOUN
biomedich-739	1	78	asfarina2	asfarina2	PROPN
biomedich-739	2	1	1biomedical	1biomedical	NUM
biomedich-739	2	2	department	department	NOUN
biomedich-739	2	3	,	,	PUNCT
biomedich-739	2	4	faculty	faculty	NOUN
biomedich-739	2	5	of	of	ADP
biomedich-739	2	6	medicine	medicine	NOUN
biomedich-739	2	7	,	,	PUNCT
biomedich-739	2	8	universitas	universita	NOUN
biomedich-739	2	9	muhammadiyah	muhammadiyah	ADP
biomedich-739	2	10	surakarta	surakarta	PROPN
biomedich-739	2	11	jl	jl	PROPN
biomedich-739	2	12	.	.	PUNCT
biomedich-739	3	1	a	a	DET
biomedich-739	3	2	yani	yani	ADJ
biomedich-739	3	3	,	,	PUNCT
biomedich-739	3	4	pabelan	pabelan	ADJ
biomedich-739	3	5	,	,	PUNCT
biomedich-739	3	6	kartasura	kartasura	ADJ
biomedich-739	3	7	,	,	PUNCT
biomedich-739	3	8	sukoharjo	sukoharjo	PROPN
biomedich-739	3	9	,	,	PUNCT
biomedich-739	3	10	jawa	jawa	PROPN
biomedich-739	3	11	tengah	tengah	PROPN
biomedich-739	3	12	57169	57169	NUM
biomedich-739	3	13	,	,	PUNCT
biomedich-739	3	14	tel	tel	PROPN
biomedich-739	3	15	.	.	PUNCT
biomedich-739	3	16	+62	+62	PROPN
biomedich-739	3	17	-	-	PUNCT
biomedich-739	3	18	271	271	NUM
biomedich-739	3	19	-	-	SYM
biomedich-739	3	20	717417	717417	NUM
biomedich-739	3	21	,	,	PUNCT
biomedich-739	3	22	fax	fax	NOUN
biomedich-739	3	23	.	.	PROPN
biomedich-739	4	1	+62	+62	PROPN
biomedich-739	4	2	-	-	PUNCT
biomedich-739	4	3	271	271	NUM
biomedich-739	4	4	-	-	SYM
biomedich-739	4	5	715448	715448	NUM
biomedich-739	4	6	,	,	PUNCT
biomedich-739	4	7	indonesia	indonesia	PROPN
biomedich-739	4	8	.	.	PUNCT
biomedich-739	5	1	2integrated	2integrated	NUM
biomedich-739	5	2	research	research	NOUN
biomedich-739	5	3	laboratory	laboratory	NOUN
biomedich-739	5	4	,	,	PUNCT
biomedich-739	5	5	faculty	faculty	NOUN
biomedich-739	5	6	of	of	ADP
biomedich-739	5	7	medicine	medicine	NOUN
biomedich-739	5	8	,	,	PUNCT
biomedich-739	5	9	nursing	nursing	NOUN
biomedich-739	5	10	,	,	PUNCT
biomedich-739	5	11	and	and	CCONJ
biomedich-739	5	12	public	public	ADJ
biomedich-739	5	13	health	health	NOUN
biomedich-739	5	14	,	,	PUNCT
biomedich-739	5	15	universitas	universita	NOUN
biomedich-739	5	16	gadjah	gadjah	PROPN
biomedich-739	5	17	mada	mada	PROPN
biomedich-739	5	18	jl	jl	PROPN
biomedich-739	5	19	.	.	PROPN
biomedich-739	6	1	farmako	farmako	PROPN
biomedich-739	6	2	sekip	sekip	ADJ
biomedich-739	6	3	utara	utara	NOUN
biomedich-739	6	4	,	,	PUNCT
biomedich-739	6	5	yogyakarta	yogyakarta	PROPN
biomedich-739	6	6	55281	55281	NUM
biomedich-739	6	7	,	,	PUNCT
biomedich-739	6	8	tel	tel	PROPN
biomedich-739	6	9	.	.	PUNCT
biomedich-739	7	1	+62	+62	PROPN
biomedich-739	7	2	-	-	PUNCT
biomedich-739	7	3	274	274	NUM
biomedich-739	7	4	-	-	PUNCT
biomedich-739	7	5	560300	560300	NUM
biomedich-739	7	6	,	,	PUNCT
biomedich-739	7	7	fax	fax	NOUN
biomedich-739	7	8	.	.	PROPN
biomedich-739	8	1	+62	+62	PROPN
biomedich-739	8	2	-	-	PUNCT
biomedich-739	8	3	274	274	NUM
biomedich-739	8	4	-	-	PUNCT
biomedich-739	8	5	581876	581876	NUM
biomedich-739	8	6	,	,	PUNCT
biomedich-739	8	7	indonesia	indonesia	PROPN
biomedich-739	8	8	.	.	PUNCT
biomedich-739	9	1	corresponding	correspond	VERB
biomedich-739	9	2	author	author	NOUN
biomedich-739	9	3	*	*	PUNCT
biomedich-739	9	4	riandini.aisyah@ums.ac.id	riandini.aisyah@ums.ac.id	NOUN
biomedich-739	9	5	manuscript	manuscript	NOUN
biomedich-739	9	6	received	receive	VERB
biomedich-739	9	7	:	:	PUNCT
biomedich-739	9	8	11	11	NUM
biomedich-739	9	9	march	march	NOUN
biomedich-739	9	10	,	,	PUNCT
biomedich-739	9	11	2025	2025	NUM
biomedich-739	9	12	.	.	PUNCT
biomedich-739	10	1	revision	revision	NOUN
biomedich-739	10	2	accepted	accept	VERB
biomedich-739	10	3	:	:	PUNCT
biomedich-739	10	4	20	20	NUM
biomedich-739	10	5	may	may	NOUN
biomedich-739	10	6	,	,	PUNCT
biomedich-739	10	7	2025	2025	NUM
biomedich-739	10	8	.	.	PUNCT
biomedich-739	11	1	published	publish	VERB
biomedich-739	11	2	:	:	PUNCT
biomedich-739	11	3	04	04	NUM
biomedich-739	11	4	july	july	PROPN
biomedich-739	11	5	,	,	PUNCT
biomedich-739	11	6	2025	2025	NUM
biomedich-739	11	7	.	.	PUNCT
biomedich-739	12	1	abstract	abstract	ADJ
biomedich-739	12	2	diabetes	diabetes	NOUN
biomedich-739	12	3	mellitus	mellitus	NOUN
biomedich-739	12	4	involves	involve	VERB
biomedich-739	12	5	many	many	ADJ
biomedich-739	12	6	mechanisms	mechanism	NOUN
biomedich-739	12	7	.	.	PUNCT
biomedich-739	13	1	the	the	DET
biomedich-739	13	2	collagen	collagen	NOUN
biomedich-739	13	3	metabolism	metabolism	NOUN
biomedich-739	13	4	pathway	pathway	NOUN
biomedich-739	13	5	with	with	ADP
biomedich-739	13	6	very	very	ADV
biomedich-739	13	7	complex	complex	ADJ
biomedich-739	13	8	interactions	interaction	NOUN
biomedich-739	13	9	and	and	CCONJ
biomedich-739	13	10	its	its	PRON
biomedich-739	13	11	regulation	regulation	NOUN
biomedich-739	13	12	can	can	AUX
biomedich-739	13	13	contribute	contribute	VERB
biomedich-739	13	14	to	to	ADP
biomedich-739	13	15	the	the	DET
biomedich-739	13	16	development	development	NOUN
biomedich-739	13	17	of	of	ADP
biomedich-739	13	18	diabetes	diabetes	NOUN
biomedich-739	13	19	complications	complication	NOUN
biomedich-739	13	20	.	.	PUNCT
biomedich-739	14	1	the	the	DET
biomedich-739	14	2	collagen	collagen	NOUN
biomedich-739	14	3	1	1	NUM
biomedich-739	14	4	alpha	alpha	NOUN
biomedich-739	14	5	1	1	NUM
biomedich-739	14	6	(	(	PUNCT
biomedich-739	14	7	col1a1	col1a1	NOUN
biomedich-739	14	8	)	)	PUNCT
biomedich-739	14	9	plays	play	VERB
biomedich-739	14	10	an	an	DET
biomedich-739	14	11	important	important	ADJ
biomedich-739	14	12	role	role	NOUN
biomedich-739	14	13	in	in	ADP
biomedich-739	14	14	the	the	DET
biomedich-739	14	15	diabetes	diabetes	NOUN
biomedich-739	14	16	melitus	melitus	NOUN
biomedich-739	14	17	pathway	pathway	NOUN
biomedich-739	14	18	in	in	ADP
biomedich-739	14	19	adipose	adipose	ADJ
biomedich-739	14	20	tissue	tissue	NOUN
biomedich-739	14	21	by	by	ADP
biomedich-739	14	22	regulating	regulate	VERB
biomedich-739	14	23	adipocyte	adipocyte	NOUN
biomedich-739	14	24	function	function	NOUN
biomedich-739	14	25	,	,	PUNCT
biomedich-739	14	26	insulin	insulin	NOUN
biomedich-739	14	27	resistance	resistance	NOUN
biomedich-739	14	28	,	,	PUNCT
biomedich-739	14	29	and	and	CCONJ
biomedich-739	14	30	glucose	glucose	NOUN
biomedich-739	14	31	metabolism	metabolism	NOUN
biomedich-739	14	32	and	and	CCONJ
biomedich-739	14	33	is	be	AUX
biomedich-739	14	34	identified	identify	VERB
biomedich-739	14	35	as	as	ADP
biomedich-739	14	36	a	a	DET
biomedich-739	14	37	potential	potential	ADJ
biomedich-739	14	38	therapeutic	therapeutic	ADJ
biomedich-739	14	39	target	target	NOUN
biomedich-739	14	40	for	for	ADP
biomedich-739	14	41	type	type	NOUN
biomedich-739	14	42	2	2	NUM
biomedich-739	14	43	diabetes	diabetes	NOUN
biomedich-739	14	44	.	.	PUNCT
biomedich-739	15	1	the	the	DET
biomedich-739	15	2	cat	cat	NOUN
biomedich-739	15	3	's	's	PART
biomedich-739	15	4	whisker	whisker	NOUN
biomedich-739	15	5	plant	plant	NOUN
biomedich-739	15	6	(	(	PUNCT
biomedich-739	15	7	ortosiphon	ortosiphon	ADJ
biomedich-739	15	8	aristatus	aristatus	NOUN
biomedich-739	15	9	)	)	PUNCT
biomedich-739	15	10	pharmacologically	pharmacologically	ADV
biomedich-739	15	11	has	have	VERB
biomedich-739	15	12	hypoglycemic	hypoglycemic	ADJ
biomedich-739	15	13	activity	activity	NOUN
biomedich-739	15	14	and	and	CCONJ
biomedich-739	15	15	increases	increase	VERB
biomedich-739	15	16	insulin	insulin	NOUN
biomedich-739	15	17	expression	expression	NOUN
biomedich-739	15	18	.	.	PUNCT
biomedich-739	16	1	this	this	DET
biomedich-739	16	2	study	study	NOUN
biomedich-739	16	3	aimed	aim	VERB
biomedich-739	16	4	to	to	PART
biomedich-739	16	5	observe	observe	VERB
biomedich-739	16	6	the	the	DET
biomedich-739	16	7	potential	potential	NOUN
biomedich-739	16	8	of	of	ADP
biomedich-739	16	9	cat	cat	NOUN
biomedich-739	16	10	whisker	whisker	NOUN
biomedich-739	16	11	leaf	leaf	NOUN
biomedich-739	16	12	extract	extract	NOUN
biomedich-739	16	13	(	(	PUNCT
biomedich-739	16	14	ortosiphon	ortosiphon	ADJ
biomedich-739	16	15	aristatus	aristatus	NOUN
biomedich-739	16	16	)	)	PUNCT
biomedich-739	16	17	in	in	ADP
biomedich-739	16	18	increasing	increase	VERB
biomedich-739	16	19	the	the	DET
biomedich-739	16	20	col1a1	col1a1	NOUN
biomedich-739	16	21	expression	expression	NOUN
biomedich-739	16	22	and	and	CCONJ
biomedich-739	16	23	is	be	AUX
biomedich-739	16	24	protective	protective	ADJ
biomedich-739	16	25	against	against	ADP
biomedich-739	16	26	increased	increase	VERB
biomedich-739	16	27	blood	blood	NOUN
biomedich-739	16	28	sugar	sugar	NOUN
biomedich-739	16	29	levels	level	NOUN
biomedich-739	16	30	in	in	ADP
biomedich-739	16	31	hyperglycemia	hyperglycemia	NOUN
biomedich-739	16	32	-	-	PUNCT
biomedich-739	16	33	induced	induce	VERB
biomedich-739	16	34	rattus	rattus	NOUN
biomedich-739	16	35	norvegicus	norvegicus	PROPN
biomedich-739	16	36	.	.	PUNCT
biomedich-739	17	1	the	the	DET
biomedich-739	17	2	experimental	experimental	ADJ
biomedich-739	17	3	design	design	NOUN
biomedich-739	17	4	with	with	ADP
biomedich-739	17	5	pretest	pret	ADJ
biomedich-739	17	6	and	and	CCONJ
biomedich-739	17	7	posttest	posttest	ADV
biomedich-739	17	8	controlled	control	VERB
biomedich-739	17	9	group	group	NOUN
biomedich-739	17	10	design	design	NOUN
biomedich-739	17	11	was	be	AUX
biomedich-739	17	12	carried	carry	VERB
biomedich-739	17	13	out	out	ADP
biomedich-739	17	14	by	by	ADP
biomedich-739	17	15	dividing	divide	VERB
biomedich-739	17	16	18	18	NUM
biomedich-739	17	17	test	test	NOUN
biomedich-739	17	18	animals	animal	NOUN
biomedich-739	17	19	into	into	ADP
biomedich-739	17	20	six	six	NUM
biomedich-739	17	21	groups	group	NOUN
biomedich-739	17	22	:	:	PUNCT
biomedich-739	17	23	non	non	ADJ
biomedich-739	17	24	-	-	ADJ
biomedich-739	17	25	diabetic	diabetic	ADJ
biomedich-739	17	26	negative	negative	ADJ
biomedich-739	17	27	control	control	NOUN
biomedich-739	17	28	,	,	PUNCT
biomedich-739	17	29	diabetic	diabetic	ADJ
biomedich-739	17	30	negative	negative	ADJ
biomedich-739	17	31	control	control	NOUN
biomedich-739	17	32	,	,	PUNCT
biomedich-739	17	33	positive	positive	ADJ
biomedich-739	17	34	control	control	NOUN
biomedich-739	17	35	(	(	PUNCT
biomedich-739	17	36	metformin	metformin	NOUN
biomedich-739	17	37	)	)	PUNCT
biomedich-739	17	38	,	,	PUNCT
biomedich-739	17	39	cat	cat	NOUN
biomedich-739	17	40	whisker	whisker	NOUN
biomedich-739	17	41	leaf	leaf	NOUN
biomedich-739	17	42	extract	extract	NOUN
biomedich-739	17	43	doses	dose	NOUN
biomedich-739	17	44	of	of	ADP
biomedich-739	17	45	100	100	NUM
biomedich-739	17	46	,	,	PUNCT
biomedich-739	17	47	200	200	NUM
biomedich-739	17	48	,	,	PUNCT
biomedich-739	17	49	and	and	CCONJ
biomedich-739	17	50	400	400	NUM
biomedich-739	17	51	mg	mg	PROPN
biomedich-739	17	52	/	/	SYM
biomedich-739	17	53	kgbw	kgbw	PROPN
biomedich-739	17	54	.	.	PUNCT
biomedich-739	18	1	induction	induction	NOUN
biomedich-739	18	2	of	of	ADP
biomedich-739	18	3	hyperglycemia	hyperglycemia	NOUN
biomedich-739	18	4	with	with	ADP
biomedich-739	18	5	streptozotocin	streptozotocin	PROPN
biomedich-739	18	6	65	65	NUM
biomedich-739	18	7	mg	mg	PROPN
biomedich-739	18	8	/	/	SYM
biomedich-739	18	9	kgbw	kgbw	NOUN
biomedich-739	18	10	and	and	CCONJ
biomedich-739	18	11	nicotinamide	nicotinamide	NOUN
biomedich-739	18	12	230	230	NUM
biomedich-739	18	13	mg	mg	PROPN
biomedich-739	18	14	/	/	SYM
biomedich-739	18	15	kgbw	kgbw	ADJ
biomedich-739	18	16	peritoneal	peritoneal	ADJ
biomedich-739	18	17	injection	injection	NOUN
biomedich-739	18	18	.	.	PUNCT
biomedich-739	19	1	the	the	DET
biomedich-739	19	2	extract	extract	NOUN
biomedich-739	19	3	treatment	treatment	NOUN
biomedich-739	19	4	was	be	AUX
biomedich-739	19	5	given	give	VERB
biomedich-739	19	6	for	for	ADP
biomedich-739	19	7	14	14	NUM
biomedich-739	19	8	days	day	NOUN
biomedich-739	19	9	.	.	PUNCT
biomedich-739	20	1	blood	blood	NOUN
biomedich-739	20	2	sugar	sugar	NOUN
biomedich-739	20	3	level	level	NOUN
biomedich-739	20	4	measurements	measurement	NOUN
biomedich-739	20	5	were	be	AUX
biomedich-739	20	6	carried	carry	VERB
biomedich-739	20	7	out	out	ADP
biomedich-739	20	8	at	at	ADP
biomedich-739	20	9	the	the	DET
biomedich-739	20	10	treatment	treatment	NOUN
biomedich-739	20	11	’s	’s	PART
biomedich-739	20	12	beginning	beginning	NOUN
biomedich-739	20	13	and	and	CCONJ
biomedich-739	20	14	end	end	NOUN
biomedich-739	20	15	.	.	PUNCT
biomedich-739	21	1	adipose	adipose	ADJ
biomedich-739	21	2	tissue	tissue	NOUN
biomedich-739	21	3	was	be	AUX
biomedich-739	21	4	taken	take	VERB
biomedich-739	21	5	to	to	PART
biomedich-739	21	6	examine	examine	VERB
biomedich-739	21	7	col1a1	col1a1	NOUN
biomedich-739	21	8	expression	expression	NOUN
biomedich-739	21	9	by	by	ADP
biomedich-739	21	10	real	real	ADJ
biomedich-739	21	11	time	time	NOUN
biomedich-739	21	12	pcr	pcr	NOUN
biomedich-739	21	13	technique	technique	NOUN
biomedich-739	21	14	by	by	ADP
biomedich-739	21	15	calculating	calculate	VERB
biomedich-739	21	16	the	the	DET
biomedich-739	21	17	ratio	ratio	NOUN
biomedich-739	21	18	of	of	ADP
biomedich-739	21	19	the	the	DET
biomedich-739	21	20	cycle	cycle	NOUN
biomedich-739	21	21	of	of	ADP
biomedich-739	21	22	tresh	tresh	NOUN
biomedich-739	21	23	-	-	PUNCT
biomedich-739	21	24	hold	hold	NOUN
biomedich-739	21	25	col1a1	col1a1	NOUN
biomedich-739	21	26	to	to	ADP
biomedich-739	21	27	the	the	DET
biomedich-739	21	28	internal	internal	ADJ
biomedich-739	21	29	gene	gene	NOUN
biomedich-739	21	30	β	β	NOUN
biomedich-739	21	31	-	-	NOUN
biomedich-739	21	32	actin	actin	NOUN
biomedich-739	21	33	.	.	PUNCT
biomedich-739	22	1	the	the	DET
biomedich-739	22	2	results	result	NOUN
biomedich-739	22	3	of	of	ADP
biomedich-739	22	4	kruskall	kruskall	PROPN
biomedich-739	22	5	wallis	wallis	PROPN
biomedich-739	22	6	test	test	NOUN
biomedich-739	22	7	showed	show	VERB
biomedich-739	22	8	no	no	DET
biomedich-739	22	9	significant	significant	ADJ
biomedich-739	22	10	difference	difference	NOUN
biomedich-739	22	11	in	in	ADP
biomedich-739	22	12	col1a1	col1a1	NOUN
biomedich-739	22	13	expression	expression	NOUN
biomedich-739	22	14	between	between	ADP
biomedich-739	22	15	groups	group	NOUN
biomedich-739	22	16	and	and	CCONJ
biomedich-739	22	17	the	the	DET
biomedich-739	22	18	spearman	spearman	NOUN
biomedich-739	22	19	correlation	correlation	NOUN
biomedich-739	22	20	test	test	NOUN
biomedich-739	22	21	showed	show	VERB
biomedich-739	22	22	no	no	DET
biomedich-739	22	23	relationship	relationship	NOUN
biomedich-739	22	24	between	between	ADP
biomedich-739	22	25	blood	blood	NOUN
biomedich-739	22	26	sugar	sugar	NOUN
biomedich-739	22	27	levels	level	NOUN
biomedich-739	22	28	and	and	CCONJ
biomedich-739	22	29	col1a1	col1a1	NOUN
biomedich-739	22	30	expression	expression	NOUN
biomedich-739	22	31	(	(	PUNCT
biomedich-739	22	32	p>0.05	p>0.05	PROPN
biomedich-739	22	33	)	)	PUNCT
biomedich-739	22	34	.	.	PUNCT
biomedich-739	23	1	there	there	PRON
biomedich-739	23	2	was	be	VERB
biomedich-739	23	3	a	a	DET
biomedich-739	23	4	decrease	decrease	NOUN
biomedich-739	23	5	in	in	ADP
biomedich-739	23	6	blood	blood	NOUN
biomedich-739	23	7	sugar	sugar	NOUN
biomedich-739	23	8	levels	level	NOUN
biomedich-739	23	9	before	before	ADP
biomedich-739	23	10	and	and	CCONJ
biomedich-739	23	11	after	after	ADP
biomedich-739	23	12	treatment	treatment	NOUN
biomedich-739	23	13	for	for	ADP
biomedich-739	23	14	all	all	DET
biomedich-739	23	15	treatment	treatment	NOUN
biomedich-739	23	16	groups	group	NOUN
biomedich-739	23	17	.	.	PUNCT
biomedich-739	24	1	keywords	keyword	NOUN
biomedich-739	24	2	:	:	PUNCT
biomedich-739	24	3	diabetes	diabetes	NOUN
biomedich-739	24	4	melitus	melitus	NOUN
biomedich-739	24	5	;	;	PUNCT
biomedich-739	24	6	col1a1	col1a1	NOUN
biomedich-739	24	7	expression	expression	NOUN
biomedich-739	24	8	;	;	PUNCT
biomedich-739	24	9	orthosiphon	orthosiphon	ADJ
biomedich-739	24	10	aristatus	aristatus	NOUN
biomedich-739	24	11	;	;	PUNCT
biomedich-739	24	12	real	real	ADJ
biomedich-739	24	13	time	time	NOUN
biomedich-739	24	14	pcr	pcr	PROPN
biomedich-739	24	15	.	.	PUNCT
biomedich-739	24	16	abbreviations	abbreviation	NOUN
biomedich-739	24	17	:	:	PUNCT
biomedich-739	24	18	col1a1	col1a1	NOUN
biomedich-739	24	19	=	=	SYM
biomedich-739	24	20	collagen	collagen	NOUN
biomedich-739	24	21	1	1	NUM
biomedich-739	24	22	alpha	alpha	NOUN
biomedich-739	24	23	1	1	NUM
biomedich-739	24	24	,	,	PUNCT
biomedich-739	24	25	pcr	pcr	NOUN
biomedich-739	24	26	=	=	SYM
biomedich-739	24	27	polymerase	polymerase	NOUN
biomedich-739	24	28	chain	chain	NOUN
biomedich-739	24	29	reaction	reaction	NOUN
biomedich-739	24	30	introduction	introduction	NOUN
biomedich-739	24	31	globally	globally	ADV
biomedich-739	24	32	,	,	PUNCT
biomedich-739	24	33	deaths	death	NOUN
biomedich-739	24	34	due	due	ADJ
biomedich-739	24	35	to	to	ADP
biomedich-739	24	36	diabetes	diabetes	NOUN
biomedich-739	24	37	are	be	AUX
biomedich-739	24	38	projected	project	VERB
biomedich-739	24	39	to	to	PART
biomedich-739	24	40	increase	increase	VERB
biomedich-739	24	41	to	to	ADP
biomedich-739	24	42	1.59	1.59	NUM
biomedich-739	24	43	million	million	NUM
biomedich-739	24	44	and	and	CCONJ
biomedich-739	24	45	79.3	79.3	NUM
biomedich-739	24	46	million	million	NUM
biomedich-739	24	47	daly	daly	NOUN
biomedich-739	24	48	(	(	PUNCT
biomedich-739	24	49	disability	disability	NOUN
biomedich-739	24	50	adjusted	adjust	VERB
biomedich-739	24	51	life	life	NOUN
biomedich-739	24	52	years	year	NOUN
biomedich-739	24	53	)	)	PUNCT
biomedich-739	24	54	by	by	ADP
biomedich-739	24	55	20251	20251	NUM
biomedich-739	24	56	,	,	PUNCT
biomedich-739	24	57	and	and	CCONJ
biomedich-739	24	58	increase	increase	VERB
biomedich-739	24	59	to	to	ADP
biomedich-739	24	60	7,079	7,079	NUM
biomedich-739	24	61	people	people	NOUN
biomedich-739	24	62	per	per	ADP
biomedich-739	24	63	100,000	100,000	NUM
biomedich-739	24	64	by	by	ADP
biomedich-739	24	65	2030	2030	NUM
biomedich-739	24	66	with	with	ADP
biomedich-739	24	67	the	the	DET
biomedich-739	24	68	burden	burden	NOUN
biomedich-739	24	69	of	of	ADP
biomedich-739	24	70	diabetes	diabetes	NOUN
biomedich-739	24	71	varying	vary	VERB
biomedich-739	24	72	between	between	ADP
biomedich-739	24	73	regions	region	NOUN
biomedich-739	24	74	.	.	PUNCT
biomedich-739	25	1	in	in	ADP
biomedich-739	25	2	indonesia	indonesia	PROPN
biomedich-739	25	3	,	,	PUNCT
biomedich-739	25	4	the	the	DET
biomedich-739	25	5	prevalence	prevalence	NOUN
biomedich-739	25	6	of	of	ADP
biomedich-739	25	7	diabetes	diabetes	NOUN
biomedich-739	25	8	mellitus	mellitus	NOUN
biomedich-739	25	9	is	be	AUX
biomedich-739	25	10	expected	expect	VERB
biomedich-739	25	11	to	to	PART
biomedich-739	25	12	increase	increase	VERB
biomedich-739	25	13	significantly	significantly	ADV
biomedich-739	25	14	in	in	ADP
biomedich-739	25	15	the	the	DET
biomedich-739	25	16	coming	come	VERB
biomedich-739	25	17	decades	decade	NOUN
biomedich-739	25	18	from	from	ADP
biomedich-739	25	19	9.19	9.19	NUM
biomedich-739	25	20	%	%	NOUN
biomedich-739	25	21	in	in	ADP
biomedich-739	25	22	2020	2020	NUM
biomedich-739	25	23	(	(	PUNCT
biomedich-739	25	24	18.69	18.69	NUM
biomedich-739	25	25	million	million	NUM
biomedich-739	25	26	cases	case	NOUN
biomedich-739	25	27	)	)	PUNCT
biomedich-739	25	28	to	to	ADP
biomedich-739	25	29	16.09	16.09	NUM
biomedich-739	25	30	%	%	NOUN
biomedich-739	25	31	in	in	ADP
biomedich-739	25	32	2045	2045	NUM
biomedich-739	25	33	(	(	PUNCT
biomedich-739	25	34	40.7	40.7	NUM
biomedich-739	25	35	million	million	NUM
biomedich-739	25	36	cases	case	NOUN
biomedich-739	25	37	)	)	PUNCT
biomedich-739	25	38	,	,	PUNCT
biomedich-739	25	39	increasing	increase	VERB
biomedich-739	25	40	by	by	ADP
biomedich-739	25	41	75.1	75.1	NUM
biomedich-739	25	42	%	%	NOUN
biomedich-739	25	43	over	over	ADP
biomedich-739	25	44	25	25	NUM
biomedich-739	25	45	years	year	NOUN
biomedich-739	25	46	,	,	PUNCT
biomedich-739	25	47	or	or	CCONJ
biomedich-739	25	48	an	an	DET
biomedich-739	25	49	average	average	NOUN
biomedich-739	25	50	of	of	ADP
biomedich-739	25	51	3	3	NUM
biomedich-739	25	52	%	%	NOUN
biomedich-739	25	53	per	per	ADP
biomedich-739	25	54	year	year	NOUN
biomedich-739	25	55	(	(	PUNCT
biomedich-739	25	56	wahidin	wahidin	VERB
biomedich-739	25	57	et	et	PROPN
biomedich-739	25	58	al	al	PROPN
biomedich-739	25	59	.	.	PROPN
biomedich-739	25	60	,	,	PUNCT
biomedich-739	25	61	2024	2024	NUM
biomedich-739	25	62	)	)	PUNCT
biomedich-739	25	63	.	.	PUNCT
biomedich-739	26	1	the	the	DET
biomedich-739	26	2	prevalence	prevalence	NOUN
biomedich-739	26	3	of	of	ADP
biomedich-739	26	4	type	type	NOUN
biomedich-739	26	5	2	2	NUM
biomedich-739	26	6	diabetes	diabetes	NOUN
biomedich-739	26	7	follows	follow	VERB
biomedich-739	26	8	a	a	DET
biomedich-739	26	9	pattern	pattern	NOUN
biomedich-739	26	10	that	that	PRON
biomedich-739	26	11	corresponds	correspond	VERB
biomedich-739	26	12	to	to	ADP
biomedich-739	26	13	socioeconomic	socioeconomic	ADJ
biomedich-739	26	14	development	development	NOUN
biomedich-739	26	15	,	,	PUNCT
biomedich-739	26	16	with	with	ADP
biomedich-739	26	17	developed	develop	VERB
biomedich-739	26	18	regions	region	NOUN
biomedich-739	26	19	showing	show	VERB
biomedich-739	26	20	higher	high	ADJ
biomedich-739	26	21	prevalence	prevalence	NOUN
biomedich-739	26	22	rates	rate	NOUN
biomedich-739	26	23	(	(	PUNCT
biomedich-739	26	24	khan	khan	PROPN
biomedich-739	26	25	et	et	PROPN
biomedich-739	26	26	al	al	PROPN
biomedich-739	26	27	.	.	PROPN
biomedich-739	26	28	,	,	PUNCT
biomedich-739	26	29	2019	2019	NUM
biomedich-739	26	30	)	)	PUNCT
biomedich-739	26	31	.	.	PUNCT
biomedich-739	27	1	diabetes	diabetes	NOUN
biomedich-739	27	2	mellitus	mellitus	NOUN
biomedich-739	27	3	is	be	AUX
biomedich-739	27	4	a	a	DET
biomedich-739	27	5	metabolic	metabolic	NOUN
biomedich-739	27	6	disease	disease	NOUN
biomedich-739	27	7	characterized	characterize	VERB
biomedich-739	27	8	by	by	ADP
biomedich-739	27	9	disturbances	disturbance	NOUN
biomedich-739	27	10	in	in	ADP
biomedich-739	27	11	insulin	insulin	NOUN
biomedich-739	27	12	secretion	secretion	NOUN
biomedich-739	27	13	,	,	PUNCT
biomedich-739	27	14	insulin	insulin	NOUN
biomedich-739	27	15	activity	activity	NOUN
biomedich-739	27	16	,	,	PUNCT
biomedich-739	27	17	or	or	CCONJ
biomedich-739	27	18	both	both	PRON
biomedich-739	27	19	.	.	PUNCT
biomedich-739	28	1	insulin	insulin	NOUN
biomedich-739	28	2	resistance	resistance	NOUN
biomedich-739	28	3	(	(	PUNCT
biomedich-739	28	4	ri	ri	NOUN
biomedich-739	28	5	)	)	PUNCT
biomedich-739	28	6	in	in	ADP
biomedich-739	28	7	type	type	NOUN
biomedich-739	28	8	2	2	NUM
biomedich-739	28	9	diabetes	diabetes	NOUN
biomedich-739	28	10	mellitus	mellitus	NOUN
biomedich-739	28	11	(	(	PUNCT
biomedich-739	28	12	t2d	t2d	NOUN
biomedich-739	28	13	)	)	PUNCT
biomedich-739	28	14	is	be	AUX
biomedich-739	28	15	accompanied	accompany	VERB
biomedich-739	28	16	by	by	ADP
biomedich-739	28	17	dysfunction	dysfunction	NOUN
biomedich-739	28	18	of	of	ADP
biomedich-739	28	19	glycolipid	glycolipid	ADJ
biomedich-739	28	20	metabolism	metabolism	NOUN
biomedich-739	28	21	and	and	CCONJ
biomedich-739	28	22	protein	protein	NOUN
biomedich-739	28	23	biosynthesis	biosynthesis	NOUN
biomedich-739	28	24	.	.	PUNCT
biomedich-739	29	1	over	over	ADP
biomedich-739	29	2	the	the	DET
biomedich-739	29	3	past	past	ADJ
biomedich-739	29	4	few	few	ADJ
biomedich-739	29	5	decades	decade	NOUN
biomedich-739	29	6	,	,	PUNCT
biomedich-739	29	7	despite	despite	SCONJ
biomedich-739	29	8	great	great	ADJ
biomedich-739	29	9	advances	advance	NOUN
biomedich-739	29	10	in	in	ADP
biomedich-739	29	11	diabetes	diabetes	NOUN
biomedich-739	29	12	-	-	PUNCT
biomedich-739	29	13	related	relate	VERB
biomedich-739	29	14	research	research	NOUN
biomedich-739	29	15	,	,	PUNCT
biomedich-739	29	16	the	the	DET
biomedich-739	29	17	discovery	discovery	NOUN
biomedich-739	29	18	of	of	ADP
biomedich-739	29	19	specific	specific	ADJ
biomedich-739	29	20	molecular	molecular	ADJ
biomedich-739	29	21	targets	target	NOUN
biomedich-739	29	22	has	have	AUX
biomedich-739	29	23	not	not	PART
biomedich-739	29	24	been	be	AUX
biomedich-739	29	25	enough	enough	ADJ
biomedich-739	29	26	.	.	PUNCT
biomedich-739	30	1	in	in	ADP
biomedich-739	30	2	addition	addition	NOUN
biomedich-739	30	3	,	,	PUNCT
biomedich-739	30	4	there	there	PRON
biomedich-739	30	5	is	be	VERB
biomedich-739	30	6	drug	drug	NOUN
biomedich-739	30	7	resistance	resistance	NOUN
biomedich-739	30	8	and	and	CCONJ
biomedich-739	30	9	side	side	NOUN
biomedich-739	30	10	effects	effect	NOUN
biomedich-739	30	11	related	relate	VERB
biomedich-739	30	12	to	to	ADP
biomedich-739	30	13	the	the	DET
biomedich-739	30	14	use	use	NOUN
biomedich-739	30	15	of	of	ADP
biomedich-739	30	16	anti	anti	ADJ
biomedich-739	30	17	-	-	ADJ
biomedich-739	30	18	diabetic	diabetic	ADJ
biomedich-739	30	19	drugs	drug	NOUN
biomedich-739	30	20	that	that	PRON
biomedich-739	30	21	can	can	AUX
biomedich-739	30	22	reduce	reduce	VERB
biomedich-739	30	23	the	the	DET
biomedich-739	30	24	inhibition	inhibition	NOUN
biomedich-739	30	25	of	of	ADP
biomedich-739	30	26	insulin	insulin	NOUN
biomedich-739	30	27	resistance	resistance	NOUN
biomedich-739	30	28	.	.	PUNCT
biomedich-739	31	1	risk	risk	NOUN
biomedich-739	31	2	factors	factor	NOUN
biomedich-739	31	3	for	for	ADP
biomedich-739	31	4	developing	develop	VERB
biomedich-739	31	5	type	type	NOUN
biomedich-739	31	6	2	2	NUM
biomedich-739	31	7	diabetes	diabetes	NOUN
biomedich-739	31	8	mellitus	mellitus	NOUN
biomedich-739	31	9	are	be	AUX
biomedich-739	31	10	obesity	obesity	NOUN
biomedich-739	31	11	and	and	CCONJ
biomedich-739	31	12	insulin	insulin	NOUN
biomedich-739	31	13	resistance	resistance	NOUN
biomedich-739	31	14	(	(	PUNCT
biomedich-739	31	15	lin	lin	PROPN
biomedich-739	31	16	et	et	PROPN
biomedich-739	31	17	al	al	PROPN
biomedich-739	31	18	.	.	PROPN
biomedich-739	31	19	,	,	PUNCT
biomedich-739	31	20	2021	2021	NUM
biomedich-739	31	21	)	)	PUNCT
biomedich-739	31	22	.	.	PUNCT
biomedich-739	32	1	the	the	DET
biomedich-739	32	2	main	main	ADJ
biomedich-739	32	3	characteristic	characteristic	NOUN
biomedich-739	32	4	of	of	ADP
biomedich-739	32	5	obesity	obesity	NOUN
biomedich-739	32	6	and	and	CCONJ
biomedich-739	32	7	insulin	insulin	NOUN
biomedich-739	32	8	resistance	resistance	NOUN
biomedich-739	32	9	is	be	AUX
biomedich-739	32	10	the	the	DET
biomedich-739	32	11	occurrence	occurrence	NOUN
biomedich-739	32	12	of	of	ADP
biomedich-739	32	13	extracellular	extracellular	ADJ
biomedich-739	32	14	matrix	matrix	NOUN
biomedich-739	32	15	(	(	PUNCT
biomedich-739	32	16	ecm	ecm	PROPN
biomedich-739	32	17	)	)	PUNCT
biomedich-739	32	18	remodeling	remodeling	NOUN
biomedich-739	32	19	abnormalities	abnormality	NOUN
biomedich-739	32	20	in	in	ADP
biomedich-739	32	21	muscle	muscle	NOUN
biomedich-739	32	22	,	,	PUNCT
biomedich-739	32	23	liver	liver	NOUN
biomedich-739	32	24	,	,	PUNCT
biomedich-739	32	25	and	and	CCONJ
biomedich-739	32	26	adipose	adipose	ADJ
biomedich-739	32	27	tissue	tissue	NOUN
biomedich-739	32	28	.	.	PUNCT
biomedich-739	33	1	there	there	PRON
biomedich-739	33	2	is	be	VERB
biomedich-739	33	3	a	a	DET
biomedich-739	33	4	growing	grow	VERB
biomedich-739	33	5	body	body	NOUN
biomedich-739	33	6	of	of	ADP
biomedich-739	33	7	evidence	evidence	NOUN
biomedich-739	33	8	suggesting	suggest	VERB
biomedich-739	33	9	a	a	DET
biomedich-739	33	10	link	link	NOUN
biomedich-739	33	11	between	between	ADP
biomedich-739	33	12	ecm	ecm	NOUN
biomedich-739	33	13	and	and	CCONJ
biomedich-739	33	14	insulin	insulin	NOUN
biomedich-739	33	15	resistance	resistance	NOUN
biomedich-739	33	16	.	.	PUNCT
biomedich-739	34	1	although	although	SCONJ
biomedich-739	34	2	ecm	ecm	NOUN
biomedich-739	34	3	remodeling	remodeling	NOUN
biomedich-739	34	4	is	be	AUX
biomedich-739	34	5	increasingly	increasingly	ADV
biomedich-739	34	6	important	important	ADJ
biomedich-739	34	7	in	in	ADP
biomedich-739	34	8	insulin	insulin	NOUN
biomedich-739	34	9	resistance	resistance	NOUN
biomedich-739	34	10	,	,	PUNCT
biomedich-739	34	11	effective	effective	ADJ
biomedich-739	34	12	ecm	ecm	NOUN
biomedich-739	34	13	targets	target	NOUN
biomedich-739	34	14	remain	remain	VERB
biomedich-739	34	15	undefined	undefined	ADJ
biomedich-739	34	16	.	.	PUNCT
biomedich-739	35	1	collagen	collagen	NOUN
biomedich-739	35	2	is	be	AUX
biomedich-739	35	3	the	the	DET
biomedich-739	35	4	most	most	ADV
biomedich-739	35	5	abundant	abundant	ADJ
biomedich-739	35	6	component	component	NOUN
biomedich-739	35	7	of	of	ADP
biomedich-739	35	8	ecm	ecm	NOUN
biomedich-739	35	9	,	,	PUNCT
biomedich-739	35	10	consisting	consist	VERB
biomedich-739	35	11	of	of	ADP
biomedich-739	35	12	three	three	NUM
biomedich-739	35	13	α	α	PRON
biomedich-739	35	14	helical	helical	ADJ
biomedich-739	35	15	chains	chain	NOUN
biomedich-739	35	16	made	make	VERB
biomedich-739	35	17	of	of	ADP
biomedich-739	35	18	a	a	DET
biomedich-739	35	19	series	series	NOUN
biomedich-739	35	20	of	of	ADP
biomedich-739	35	21	repeating	repeat	VERB
biomedich-739	35	22	amino	amino	ADJ
biomedich-739	35	23	acids	acid	NOUN
biomedich-739	35	24	glycine	glycine	NOUN
biomedich-739	35	25	-	-	PUNCT
biomedich-739	35	26	x	x	NOUN
biomedich-739	35	27	-	-	PUNCT
biomedich-739	35	28	y.	y.	VERB
biomedich-739	35	29	an	an	DET
biomedich-739	35	30	increase	increase	NOUN
biomedich-739	35	31	in	in	ADP
biomedich-739	35	32	collagen	collagen	NOUN
biomedich-739	35	33	protein	protein	NOUN
biomedich-739	35	34	in	in	ADP
biomedich-739	35	35	insulin	insulin	NOUN
biomedich-739	35	36	-	-	PUNCT
biomedich-739	35	37	resistant	resistant	ADJ
biomedich-739	35	38	cells	cell	NOUN
biomedich-739	35	39	is	be	AUX
biomedich-739	35	40	associated	associate	VERB
biomedich-739	35	41	https://doi.org/10.14421/biomedich.2025.141.357-361	https://doi.org/10.14421/biomedich.2025.141.357-361	PROPN
biomedich-739	35	42	358	358	NUM
biomedich-739	35	43	biology	biology	NOUN
biomedich-739	35	44	,	,	PUNCT
biomedich-739	35	45	medicine	medicine	NOUN
biomedich-739	35	46	,	,	PUNCT
biomedich-739	35	47	&	&	CCONJ
biomedich-739	35	48	natural	natural	ADJ
biomedich-739	35	49	product	product	NOUN
biomedich-739	35	50	chemistry	chemistry	NOUN
biomedich-739	35	51	14	14	NUM
biomedich-739	35	52	(	(	PUNCT
biomedich-739	35	53	1	1	NUM
biomedich-739	35	54	)	)	PUNCT
biomedich-739	35	55	,	,	PUNCT
biomedich-739	35	56	2025	2025	NUM
biomedich-739	35	57	:	:	PUNCT
biomedich-739	35	58	357	357	NUM
biomedich-739	35	59	-	-	SYM
biomedich-739	35	60	361	361	NUM
biomedich-739	35	61	with	with	ADP
biomedich-739	35	62	increased	increase	VERB
biomedich-739	35	63	mrna	mrna	PROPN
biomedich-739	35	64	levels	level	NOUN
biomedich-739	35	65	.	.	PUNCT
biomedich-739	36	1	increased	increase	VERB
biomedich-739	36	2	expression	expression	NOUN
biomedich-739	36	3	of	of	ADP
biomedich-739	36	4	some	some	PRON
biomedich-739	36	5	of	of	ADP
biomedich-739	36	6	the	the	DET
biomedich-739	36	7	genes	gene	NOUN
biomedich-739	36	8	that	that	PRON
biomedich-739	36	9	make	make	VERB
biomedich-739	36	10	up	up	ADP
biomedich-739	36	11	collagen	collagen	NOUN
biomedich-739	36	12	proteins	protein	NOUN
biomedich-739	36	13	is	be	AUX
biomedich-739	36	14	associated	associate	VERB
biomedich-739	36	15	with	with	ADP
biomedich-739	36	16	a	a	DET
biomedich-739	36	17	high	high	ADJ
biomedich-739	36	18	-	-	PUNCT
biomedich-739	36	19	fat	fat	NOUN
biomedich-739	36	20	diet	diet	NOUN
biomedich-739	36	21	.	.	PUNCT
biomedich-739	37	1	the	the	DET
biomedich-739	37	2	increase	increase	NOUN
biomedich-739	37	3	in	in	ADP
biomedich-739	37	4	col24α1	col24α1	PROPN
biomedich-739	37	5	mrna	mrna	PROPN
biomedich-739	37	6	in	in	ADP
biomedich-739	37	7	the	the	DET
biomedich-739	37	8	adipose	adipose	ADJ
biomedich-739	37	9	tissue	tissue	NOUN
biomedich-739	37	10	of	of	ADP
biomedich-739	37	11	obese	obese	ADJ
biomedich-739	37	12	white	white	ADJ
biomedich-739	37	13	mice	mouse	NOUN
biomedich-739	37	14	was	be	AUX
biomedich-739	37	15	consistent	consistent	ADJ
biomedich-739	37	16	with	with	ADP
biomedich-739	37	17	the	the	DET
biomedich-739	37	18	increase	increase	NOUN
biomedich-739	37	19	in	in	ADP
biomedich-739	37	20	other	other	ADJ
biomedich-739	37	21	previously	previously	ADV
biomedich-739	37	22	reported	report	VERB
biomedich-739	37	23	collagen	collagen	NOUN
biomedich-739	37	24	isoform	isoform	NOUN
biomedich-739	37	25	mrnas	mrna	NOUN
biomedich-739	37	26	including	include	VERB
biomedich-739	37	27	col5α2	col5α2	PROPN
biomedich-739	37	28	,	,	PUNCT
biomedich-739	37	29	col6α2	col6α2	NOUN
biomedich-739	37	30	,	,	PUNCT
biomedich-739	37	31	col6α3	col6α3	ADJ
biomedich-739	37	32	and	and	CCONJ
biomedich-739	37	33	col18α1	col18α1	PROPN
biomedich-739	37	34	.	.	PUNCT
biomedich-739	38	1	studies	study	NOUN
biomedich-739	38	2	on	on	ADP
biomedich-739	38	3	the	the	DET
biomedich-739	38	4	role	role	NOUN
biomedich-739	38	5	of	of	ADP
biomedich-739	38	6	specific	specific	ADJ
biomedich-739	38	7	ecm	ecm	NOUN
biomedich-739	38	8	components	component	NOUN
biomedich-739	38	9	in	in	ADP
biomedich-739	38	10	insulin	insulin	NOUN
biomedich-739	38	11	resistance	resistance	NOUN
biomedich-739	38	12	are	be	AUX
biomedich-739	38	13	important	important	ADJ
biomedich-739	38	14	but	but	CCONJ
biomedich-739	38	15	incomplete	incomplete	ADJ
biomedich-739	38	16	(	(	PUNCT
biomedich-739	38	17	weng	weng	PROPN
biomedich-739	38	18	et	et	PROPN
biomedich-739	38	19	al	al	PROPN
biomedich-739	38	20	.	.	PROPN
biomedich-739	38	21	,	,	PUNCT
biomedich-739	38	22	2020	2020	NUM
biomedich-739	38	23	)	)	PUNCT
biomedich-739	38	24	.	.	PUNCT
biomedich-739	39	1	col1a1	col1a1	NOUN
biomedich-739	39	2	is	be	AUX
biomedich-739	39	3	the	the	DET
biomedich-739	39	4	most	most	ADV
biomedich-739	39	5	significant	significant	ADJ
biomedich-739	39	6	gene	gene	NOUN
biomedich-739	39	7	in	in	ADP
biomedich-739	39	8	the	the	DET
biomedich-739	39	9	extracellular	extracellular	ADJ
biomedich-739	39	10	matrix	matrix	NOUN
biomedich-739	39	11	receptor	receptor	NOUN
biomedich-739	39	12	interaction	interaction	NOUN
biomedich-739	39	13	pathway	pathway	NOUN
biomedich-739	39	14	and	and	CCONJ
biomedich-739	39	15	is	be	AUX
biomedich-739	39	16	associated	associate	VERB
biomedich-739	39	17	with	with	ADP
biomedich-739	39	18	hypoglycemic	hypoglycemic	ADJ
biomedich-739	39	19	activity	activity	NOUN
biomedich-739	39	20	for	for	ADP
biomedich-739	39	21	the	the	DET
biomedich-739	39	22	first	first	ADJ
biomedich-739	39	23	time	time	NOUN
biomedich-739	39	24	.	.	PUNCT
biomedich-739	40	1	thus	thus	ADV
biomedich-739	40	2	,	,	PUNCT
biomedich-739	40	3	col1a1	col1a1	NOUN
biomedich-739	40	4	is	be	AUX
biomedich-739	40	5	a	a	DET
biomedich-739	40	6	potential	potential	ADJ
biomedich-739	40	7	new	new	ADJ
biomedich-739	40	8	therapeutic	therapeutic	ADJ
biomedich-739	40	9	target	target	NOUN
biomedich-739	40	10	for	for	ADP
biomedich-739	40	11	reducing	reduce	VERB
biomedich-739	40	12	t2d	t2d	PUNCT
biomedich-739	40	13	(	(	PUNCT
biomedich-739	40	14	lin	lin	PROPN
biomedich-739	40	15	et	et	PROPN
biomedich-739	40	16	al	al	PROPN
biomedich-739	40	17	.	.	PROPN
biomedich-739	40	18	,	,	PUNCT
biomedich-739	40	19	2021	2021	NUM
biomedich-739	40	20	)	)	PUNCT
biomedich-739	40	21	.	.	PUNCT
biomedich-739	41	1	rapid	rapid	ADJ
biomedich-739	41	2	advances	advance	NOUN
biomedich-739	41	3	in	in	ADP
biomedich-739	41	4	proteomics	proteomic	NOUN
biomedich-739	41	5	are	be	AUX
biomedich-739	41	6	critical	critical	ADJ
biomedich-739	41	7	to	to	ADP
biomedich-739	41	8	uncovering	uncover	VERB
biomedich-739	41	9	the	the	DET
biomedich-739	41	10	mechanisms	mechanism	NOUN
biomedich-739	41	11	underlying	underlying	ADJ
biomedich-739	41	12	t2d	t2d	NOUN
biomedich-739	41	13	and	and	CCONJ
biomedich-739	41	14	identifying	identify	VERB
biomedich-739	41	15	mechanism	mechanism	NOUN
biomedich-739	41	16	-	-	PUNCT
biomedich-739	41	17	based	base	VERB
biomedich-739	41	18	biomarkers	biomarker	NOUN
biomedich-739	41	19	.	.	PUNCT
biomedich-739	42	1	tissue	tissue	NOUN
biomedich-739	42	2	analysis	analysis	NOUN
biomedich-739	42	3	correlated	correlate	VERB
biomedich-739	42	4	glycometabolic	glycometabolic	NOUN
biomedich-739	42	5	parameters	parameter	NOUN
biomedich-739	42	6	and	and	CCONJ
biomedich-739	42	7	dep	dep	PROPN
biomedich-739	42	8	(	(	PUNCT
biomedich-739	42	9	differentially	differentially	ADV
biomedich-739	42	10	expressed	express	VERB
biomedich-739	42	11	protein	protein	NOUN
biomedich-739	42	12	)	)	PUNCT
biomedich-739	42	13	.	.	PUNCT
biomedich-739	43	1	the	the	DET
biomedich-739	43	2	gene	gene	NOUN
biomedich-739	43	3	’s	’s	PART
biomedich-739	43	4	expression	expression	NOUN
biomedich-739	43	5	level	level	NOUN
biomedich-739	43	6	in	in	ADP
biomedich-739	43	7	the	the	DET
biomedich-739	43	8	primary	primary	ADJ
biomedich-739	43	9	metabolic	metabolic	NOUN
biomedich-739	43	10	pathway	pathway	NOUN
biomedich-739	43	11	is	be	AUX
biomedich-739	43	12	necessary	necessary	ADJ
biomedich-739	43	13	to	to	PART
biomedich-739	43	14	identify	identify	VERB
biomedich-739	43	15	biomarker	biomarker	NOUN
biomedich-739	43	16	candidates	candidate	NOUN
biomedich-739	43	17	.	.	PUNCT
biomedich-739	44	1	collagen	collagen	NOUN
biomedich-739	44	2	proteins	protein	NOUN
biomedich-739	44	3	interact	interact	VERB
biomedich-739	44	4	with	with	ADP
biomedich-739	44	5	each	each	DET
biomedich-739	44	6	other	other	ADJ
biomedich-739	44	7	so	so	ADV
biomedich-739	44	8	further	further	ADJ
biomedich-739	44	9	observation	observation	NOUN
biomedich-739	44	10	of	of	ADP
biomedich-739	44	11	collagenencoding	collagenencoding	NOUN
biomedich-739	44	12	genes	gene	NOUN
biomedich-739	44	13	is	be	AUX
biomedich-739	44	14	needed	need	VERB
biomedich-739	44	15	so	so	SCONJ
biomedich-739	44	16	that	that	SCONJ
biomedich-739	44	17	a	a	DET
biomedich-739	44	18	molecular	molecular	ADJ
biomedich-739	44	19	network	network	NOUN
biomedich-739	44	20	analysis	analysis	NOUN
biomedich-739	44	21	related	relate	VERB
biomedich-739	44	22	to	to	ADP
biomedich-739	44	23	insulin	insulin	NOUN
biomedich-739	44	24	resistance	resistance	NOUN
biomedich-739	44	25	is	be	AUX
biomedich-739	44	26	obtained	obtain	VERB
biomedich-739	44	27	(	(	PUNCT
biomedich-739	44	28	lin	lin	PROPN
biomedich-739	44	29	et	et	PROPN
biomedich-739	44	30	al	al	PROPN
biomedich-739	44	31	.	.	PROPN
biomedich-739	44	32	,	,	PUNCT
biomedich-739	44	33	2021	2021	NUM
biomedich-739	44	34	;	;	PUNCT
biomedich-739	44	35	weng	weng	PROPN
biomedich-739	44	36	et	et	PROPN
biomedich-739	44	37	al	al	PROPN
biomedich-739	44	38	.	.	PROPN
biomedich-739	44	39	,	,	PUNCT
biomedich-739	44	40	2020	2020	NUM
biomedich-739	44	41	)	)	PUNCT
biomedich-739	44	42	.	.	PUNCT
biomedich-739	45	1	diabetes	diabetes	NOUN
biomedich-739	45	2	mellitus	mellitus	NOUN
biomedich-739	45	3	as	as	ADP
biomedich-739	45	4	a	a	DET
biomedich-739	45	5	chronic	chronic	ADJ
biomedich-739	45	6	illness	illness	NOUN
biomedich-739	45	7	with	with	ADP
biomedich-739	45	8	considerable	considerable	ADJ
biomedich-739	45	9	worldwide	worldwide	ADJ
biomedich-739	45	10	repercussions	repercussion	NOUN
biomedich-739	45	11	,	,	PUNCT
biomedich-739	45	12	necessitates	necessitate	VERB
biomedich-739	45	13	appropriate	appropriate	ADJ
biomedich-739	45	14	management	management	NOUN
biomedich-739	45	15	to	to	PART
biomedich-739	45	16	avert	avert	VERB
biomedich-739	45	17	fatal	fatal	ADJ
biomedich-739	45	18	outcome	outcome	NOUN
biomedich-739	45	19	.	.	PUNCT
biomedich-739	46	1	natural	natural	ADJ
biomedich-739	46	2	pharmaceuticals	pharmaceutical	NOUN
biomedich-739	46	3	are	be	AUX
biomedich-739	46	4	becoming	become	VERB
biomedich-739	46	5	increasingly	increasingly	ADV
biomedich-739	46	6	popular	popular	ADJ
biomedich-739	46	7	due	due	ADP
biomedich-739	46	8	to	to	ADP
biomedich-739	46	9	their	their	PRON
biomedich-739	46	10	perceived	perceive	VERB
biomedich-739	46	11	safety	safety	NOUN
biomedich-739	46	12	compared	compare	VERB
biomedich-739	46	13	to	to	ADP
biomedich-739	46	14	synthetic	synthetic	ADJ
biomedich-739	46	15	drugs	drug	NOUN
biomedich-739	46	16	,	,	PUNCT
biomedich-739	46	17	despite	despite	SCONJ
biomedich-739	46	18	potentially	potentially	ADV
biomedich-739	46	19	poorer	poor	ADJ
biomedich-739	46	20	efficacy	efficacy	NOUN
biomedich-739	46	21	(	(	PUNCT
biomedich-739	46	22	septiana	septiana	PROPN
biomedich-739	46	23	et	et	PROPN
biomedich-739	46	24	al	al	PROPN
biomedich-739	46	25	.	.	PROPN
biomedich-739	46	26	,	,	PUNCT
biomedich-739	46	27	2021	2021	NUM
biomedich-739	46	28	)	)	PUNCT
biomedich-739	46	29	.	.	PUNCT
biomedich-739	47	1	two	two	NUM
biomedich-739	47	2	hundred	hundred	NUM
biomedich-739	47	3	twenty	twenty	NUM
biomedich-739	47	4	-	-	PUNCT
biomedich-739	47	5	nine	nine	NUM
biomedich-739	47	6	medicinal	medicinal	ADJ
biomedich-739	47	7	plants	plant	NOUN
biomedich-739	47	8	in	in	ADP
biomedich-739	47	9	indonesia	indonesia	PROPN
biomedich-739	47	10	have	have	AUX
biomedich-739	47	11	been	be	AUX
biomedich-739	47	12	identified	identify	VERB
biomedich-739	47	13	as	as	ADP
biomedich-739	47	14	beneficial	beneficial	ADJ
biomedich-739	47	15	for	for	ADP
biomedich-739	47	16	reducing	reduce	VERB
biomedich-739	47	17	blood	blood	NOUN
biomedich-739	47	18	glucose	glucose	NOUN
biomedich-739	47	19	levels	level	NOUN
biomedich-739	47	20	.	.	PUNCT
biomedich-739	48	1	the	the	DET
biomedich-739	48	2	asteraceae	asteraceae	PROPN
biomedich-739	48	3	family	family	PROPN
biomedich-739	48	4	and	and	CCONJ
biomedich-739	48	5	orthosiphon	orthosiphon	ADJ
biomedich-739	48	6	aristatus	aristatus	NOUN
biomedich-739	48	7	species	specie	NOUN
biomedich-739	48	8	were	be	AUX
biomedich-739	48	9	the	the	DET
biomedich-739	48	10	most	most	ADV
biomedich-739	48	11	predominant	predominant	ADJ
biomedich-739	48	12	.	.	PUNCT
biomedich-739	49	1	it	it	PRON
biomedich-739	49	2	underscored	underscore	VERB
biomedich-739	49	3	the	the	DET
biomedich-739	49	4	necessity	necessity	NOUN
biomedich-739	49	5	confirming	confirm	VERB
biomedich-739	49	6	pharmacological	pharmacological	ADJ
biomedich-739	49	7	activity	activity	NOUN
biomedich-739	49	8	at	at	ADP
biomedich-739	49	9	the	the	DET
biomedich-739	49	10	molecular	molecular	ADJ
biomedich-739	49	11	level	level	NOUN
biomedich-739	49	12	(	(	PUNCT
biomedich-739	49	13	arifah	arifah	X
biomedich-739	49	14	et	et	PROPN
biomedich-739	49	15	al	al	PROPN
biomedich-739	49	16	.	.	PROPN
biomedich-739	49	17	,	,	PUNCT
biomedich-739	49	18	2022	2022	NUM
biomedich-739	49	19	)	)	PUNCT
biomedich-739	49	20	.	.	PUNCT
biomedich-739	50	1	the	the	DET
biomedich-739	50	2	leaves	leave	NOUN
biomedich-739	50	3	of	of	ADP
biomedich-739	50	4	the	the	DET
biomedich-739	50	5	cat	cat	NOUN
biomedich-739	50	6	's	's	PART
biomedich-739	50	7	whisker	whisker	NOUN
biomedich-739	50	8	plant	plant	NOUN
biomedich-739	50	9	(	(	PUNCT
biomedich-739	50	10	ortosiphon	ortosiphon	ADJ
biomedich-739	50	11	aristatus	aristatus	NOUN
biomedich-739	50	12	)	)	PUNCT
biomedich-739	50	13	contain	contain	VERB
biomedich-739	50	14	various	various	ADJ
biomedich-739	50	15	active	active	ADJ
biomedich-739	50	16	substances	substance	NOUN
biomedich-739	50	17	(	(	PUNCT
biomedich-739	50	18	nurcholis	nurcholi	NOUN
biomedich-739	50	19	et	et	NOUN
biomedich-739	50	20	al	al	PROPN
biomedich-739	50	21	.	.	PROPN
biomedich-739	50	22	,	,	PUNCT
biomedich-739	50	23	2022	2022	NUM
biomedich-739	50	24	)	)	PUNCT
biomedich-739	50	25	.	.	PUNCT
biomedich-739	51	1	the	the	DET
biomedich-739	51	2	methanol	methanol	NOUN
biomedich-739	51	3	and	and	CCONJ
biomedich-739	51	4	ethanol	ethanol	NOUN
biomedich-739	51	5	extracts	extract	NOUN
biomedich-739	51	6	of	of	ADP
biomedich-739	51	7	ortosiphon	ortosiphon	ADJ
biomedich-739	51	8	aristatus	aristatus	NOUN
biomedich-739	51	9	exhibited	exhibit	VERB
biomedich-739	51	10	remarkable	remarkable	ADJ
biomedich-739	51	11	αglucosidase	αglucosidase	NOUN
biomedich-739	51	12	inhibitory	inhibitory	ADJ
biomedich-739	51	13	activity	activity	NOUN
biomedich-739	51	14	,	,	PUNCT
biomedich-739	51	15	enhancing	enhance	VERB
biomedich-739	51	16	the	the	DET
biomedich-739	51	17	recognition	recognition	NOUN
biomedich-739	51	18	of	of	ADP
biomedich-739	51	19	the	the	DET
biomedich-739	51	20	bioactive	bioactive	ADJ
biomedich-739	51	21	substances	substance	NOUN
biomedich-739	51	22	in	in	ADP
biomedich-739	51	23	ortosiphon	ortosiphon	ADJ
biomedich-739	51	24	aristatus	aristatus	NOUN
biomedich-739	51	25	for	for	ADP
biomedich-739	51	26	diabetes	diabetes	NOUN
biomedich-739	51	27	management	management	NOUN
biomedich-739	51	28	(	(	PUNCT
biomedich-739	51	29	maulana	maulana	PROPN
biomedich-739	51	30	et	et	PROPN
biomedich-739	51	31	al	al	PROPN
biomedich-739	51	32	.	.	PROPN
biomedich-739	51	33	,	,	PUNCT
biomedich-739	51	34	2022	2022	NUM
biomedich-739	51	35	)	)	PUNCT
biomedich-739	51	36	.	.	PUNCT
biomedich-739	52	1	ortosiphon	ortosiphon	ADJ
biomedich-739	52	2	aristatus	aristatus	NOUN
biomedich-739	52	3	extracts	extract	NOUN
biomedich-739	52	4	showed	show	VERB
biomedich-739	52	5	considerable	considerable	ADJ
biomedich-739	52	6	hypoglycemics	hypoglycemic	NOUN
biomedich-739	52	7	efficacy	efficacy	NOUN
biomedich-739	52	8	compared	compare	VERB
biomedich-739	52	9	to	to	ADP
biomedich-739	52	10	the	the	DET
biomedich-739	52	11	diabetes	diabetes	NOUN
biomedich-739	52	12	control	control	NOUN
biomedich-739	52	13	group	group	NOUN
biomedich-739	52	14	,	,	PUNCT
biomedich-739	52	15	less	less	ADJ
biomedich-739	52	16	toxicity	toxicity	NOUN
biomedich-739	52	17	,	,	PUNCT
biomedich-739	52	18	suggesting	suggest	VERB
biomedich-739	52	19	promise	promise	NOUN
biomedich-739	52	20	for	for	ADP
biomedich-739	52	21	herbal	herbal	ADJ
biomedich-739	52	22	treatment	treatment	NOUN
biomedich-739	52	23	(	(	PUNCT
biomedich-739	52	24	thinn	thinn	NOUN
biomedich-739	52	25	et	et	NOUN
biomedich-739	52	26	al	al	PROPN
biomedich-739	52	27	.	.	PROPN
biomedich-739	52	28	,	,	PUNCT
biomedich-739	52	29	2018	2018	NUM
biomedich-739	52	30	)	)	PUNCT
biomedich-739	52	31	.	.	PUNCT
biomedich-739	53	1	the	the	DET
biomedich-739	53	2	content	content	NOUN
biomedich-739	53	3	of	of	ADP
biomedich-739	53	4	flavonoids	flavonoid	NOUN
biomedich-739	53	5	plays	play	VERB
biomedich-739	53	6	a	a	DET
biomedich-739	53	7	role	role	NOUN
biomedich-739	53	8	in	in	ADP
biomedich-739	53	9	lowering	lower	VERB
biomedich-739	53	10	blood	blood	NOUN
biomedich-739	53	11	sugar	sugar	NOUN
biomedich-739	53	12	levels	level	NOUN
biomedich-739	53	13	and	and	CCONJ
biomedich-739	53	14	modulating	modulate	VERB
biomedich-739	53	15	oxidative	oxidative	ADJ
biomedich-739	53	16	stress	stress	NOUN
biomedich-739	53	17	in	in	ADP
biomedich-739	53	18	the	the	DET
biomedich-739	53	19	body	body	NOUN
biomedich-739	53	20	by	by	ADP
biomedich-739	53	21	neutralizing	neutralize	VERB
biomedich-739	53	22	the	the	DET
biomedich-739	53	23	effects	effect	NOUN
biomedich-739	53	24	of	of	ADP
biomedich-739	53	25	nitrogen	nitrogen	NOUN
biomedich-739	53	26	and	and	CCONJ
biomedich-739	53	27	oxygen	oxygen	NOUN
biomedich-739	53	28	species	specie	NOUN
biomedich-739	53	29	.	.	PUNCT
biomedich-739	54	1	flavonoids	flavonoid	NOUN
biomedich-739	54	2	help	help	VERB
biomedich-739	54	3	regulate	regulate	VERB
biomedich-739	54	4	carbohydrate	carbohydrate	ADJ
biomedich-739	54	5	digestion	digestion	NOUN
biomedich-739	54	6	,	,	PUNCT
biomedich-739	54	7	insulin	insulin	NOUN
biomedich-739	54	8	signaling	signaling	NOUN
biomedich-739	54	9	,	,	PUNCT
biomedich-739	54	10	insulin	insulin	NOUN
biomedich-739	54	11	secretion	secretion	NOUN
biomedich-739	54	12	,	,	PUNCT
biomedich-739	54	13	glucose	glucose	NOUN
biomedich-739	54	14	absorption	absorption	NOUN
biomedich-739	54	15	,	,	PUNCT
biomedich-739	54	16	and	and	CCONJ
biomedich-739	54	17	adipose	adipose	NOUN
biomedich-739	54	18	.	.	PUNCT
biomedich-739	55	1	flavonoids	flavonoid	NOUN
biomedich-739	55	2	target	target	VERB
biomedich-739	55	3	many	many	ADJ
biomedich-739	55	4	molecules	molecule	NOUN
biomedich-739	55	5	involved	involve	VERB
biomedich-739	55	6	in	in	ADP
biomedich-739	55	7	regulating	regulate	VERB
biomedich-739	55	8	several	several	ADJ
biomedich-739	55	9	pathways	pathway	NOUN
biomedich-739	55	10	,	,	PUNCT
biomedich-739	55	11	such	such	ADJ
biomedich-739	55	12	as	as	ADP
biomedich-739	55	13	increasing	increase	VERB
biomedich-739	55	14	ß	ß	DET
biomedich-739	55	15	cell	cell	NOUN
biomedich-739	55	16	proliferation	proliferation	NOUN
biomedich-739	55	17	,	,	PUNCT
biomedich-739	55	18	increasing	increase	VERB
biomedich-739	55	19	insulin	insulin	NOUN
biomedich-739	55	20	secretion	secretion	NOUN
biomedich-739	55	21	,	,	PUNCT
biomedich-739	55	22	reducing	reduce	VERB
biomedich-739	55	23	apoptosis	apoptosis	NOUN
biomedich-739	55	24	,	,	PUNCT
biomedich-739	55	25	and	and	CCONJ
biomedich-739	55	26	improving	improve	VERB
biomedich-739	55	27	hyperglycemia	hyperglycemia	NOUN
biomedich-739	55	28	by	by	ADP
biomedich-739	55	29	regulating	regulate	VERB
biomedich-739	55	30	glucose	glucose	NOUN
biomedich-739	55	31	metabolism	metabolism	NOUN
biomedich-739	55	32	in	in	ADP
biomedich-739	55	33	the	the	DET
biomedich-739	55	34	liver	liver	NOUN
biomedich-739	55	35	(	(	PUNCT
biomedich-739	55	36	ojo	ojo	NOUN
biomedich-739	55	37	et	et	PROPN
biomedich-739	55	38	al	al	PROPN
biomedich-739	55	39	.	.	PROPN
biomedich-739	55	40	,	,	PUNCT
biomedich-739	55	41	2023	2023	NUM
biomedich-739	55	42	)	)	PUNCT
biomedich-739	55	43	.	.	PUNCT
biomedich-739	56	1	this	this	DET
biomedich-739	56	2	study	study	NOUN
biomedich-739	56	3	aimed	aim	VERB
biomedich-739	56	4	to	to	PART
biomedich-739	56	5	observe	observe	VERB
biomedich-739	56	6	the	the	DET
biomedich-739	56	7	potential	potential	NOUN
biomedich-739	56	8	of	of	ADP
biomedich-739	56	9	cat	cat	NOUN
biomedich-739	56	10	whisker	whisker	NOUN
biomedich-739	56	11	leaf	leaf	NOUN
biomedich-739	56	12	extract	extract	NOUN
biomedich-739	56	13	(	(	PUNCT
biomedich-739	56	14	ortosiphon	ortosiphon	ADJ
biomedich-739	56	15	aristatus	aristatus	NOUN
biomedich-739	56	16	)	)	PUNCT
biomedich-739	56	17	in	in	ADP
biomedich-739	56	18	increasing	increase	VERB
biomedich-739	56	19	the	the	DET
biomedich-739	56	20	expression	expression	NOUN
biomedich-739	56	21	of	of	ADP
biomedich-739	56	22	the	the	DET
biomedich-739	56	23	col1a1	col1a1	NOUN
biomedich-739	56	24	gene	gene	NOUN
biomedich-739	56	25	.	.	PUNCT
biomedich-739	57	1	observation	observation	NOUN
biomedich-739	57	2	of	of	ADP
biomedich-739	57	3	the	the	DET
biomedich-739	57	4	expression	expression	NOUN
biomedich-739	57	5	of	of	ADP
biomedich-739	57	6	the	the	DET
biomedich-739	57	7	mrna	mrna	PROPN
biomedich-739	57	8	gene	gene	PROPN
biomedich-739	57	9	col1a1	col1a1	PROPN
biomedich-739	57	10	as	as	ADP
biomedich-739	57	11	a	a	DET
biomedich-739	57	12	gene	gene	NOUN
biomedich-739	57	13	encoding	encode	VERB
biomedich-739	57	14	one	one	NUM
biomedich-739	57	15	of	of	ADP
biomedich-739	57	16	the	the	DET
biomedich-739	57	17	collagen	collagen	NOUN
biomedich-739	57	18	proteins	protein	NOUN
biomedich-739	57	19	from	from	ADP
biomedich-739	57	20	adipose	adipose	PRON
biomedich-739	57	21	tissue	tissue	NOUN
biomedich-739	57	22	is	be	AUX
biomedich-739	57	23	important	important	ADJ
biomedich-739	57	24	because	because	SCONJ
biomedich-739	57	25	the	the	DET
biomedich-739	57	26	col1a1	col1a1	NOUN
biomedich-739	57	27	gene	gene	NOUN
biomedich-739	57	28	is	be	AUX
biomedich-739	57	29	involved	involve	VERB
biomedich-739	57	30	in	in	ADP
biomedich-739	57	31	the	the	DET
biomedich-739	57	32	mechanism	mechanism	NOUN
biomedich-739	57	33	of	of	ADP
biomedich-739	57	34	insulin	insulin	NOUN
biomedich-739	57	35	resistance	resistance	NOUN
biomedich-739	57	36	with	with	ADP
biomedich-739	57	37	obesity	obesity	NOUN
biomedich-739	57	38	risk	risk	NOUN
biomedich-739	57	39	factors	factor	NOUN
biomedich-739	57	40	.	.	PUNCT
biomedich-739	58	1	there	there	PRON
biomedich-739	58	2	is	be	VERB
biomedich-739	58	3	a	a	DET
biomedich-739	58	4	contradiction	contradiction	NOUN
biomedich-739	58	5	between	between	ADP
biomedich-739	58	6	the	the	DET
biomedich-739	58	7	results	result	NOUN
biomedich-739	58	8	of	of	ADP
biomedich-739	58	9	the	the	DET
biomedich-739	58	10	col1a1	col1a1	NOUN
biomedich-739	58	11	gene	gene	NOUN
biomedich-739	58	12	research	research	NOUN
biomedich-739	58	13	with	with	ADP
biomedich-739	58	14	the	the	DET
biomedich-739	58	15	protective	protective	ADJ
biomedich-739	58	16	properties	property	NOUN
biomedich-739	58	17	of	of	ADP
biomedich-739	58	18	col1a1	col1a1	NOUN
biomedich-739	58	19	gene	gene	NOUN
biomedich-739	58	20	expression	expression	NOUN
biomedich-739	58	21	against	against	ADP
biomedich-739	58	22	increased	increase	VERB
biomedich-739	58	23	blood	blood	NOUN
biomedich-739	58	24	sugar	sugar	NOUN
biomedich-739	58	25	and	and	CCONJ
biomedich-739	58	26	vice	vice	NOUN
biomedich-739	58	27	versa	versa	ADV
biomedich-739	58	28	.	.	PUNCT
biomedich-739	59	1	materials	material	NOUN
biomedich-739	59	2	and	and	CCONJ
biomedich-739	59	3	methods	method	NOUN
biomedich-739	59	4	study	study	NOUN
biomedich-739	59	5	area	area	NOUN
biomedich-739	59	6	extracts	extract	NOUN
biomedich-739	59	7	preparation	preparation	NOUN
biomedich-739	59	8	,	,	PUNCT
biomedich-739	59	9	test	test	NOUN
biomedich-739	59	10	animals	animal	NOUN
biomedich-739	59	11	treatment	treatment	NOUN
biomedich-739	59	12	,	,	PUNCT
biomedich-739	59	13	blood	blood	NOUN
biomedich-739	59	14	sugar	sugar	NOUN
biomedich-739	59	15	levels	level	NOUN
biomedich-739	59	16	measurement	measurement	NOUN
biomedich-739	59	17	,	,	PUNCT
biomedich-739	59	18	and	and	CCONJ
biomedich-739	59	19	adipose	adipose	PRON
biomedich-739	59	20	tissue	tissue	NOUN
biomedich-739	59	21	collection	collection	NOUN
biomedich-739	59	22	were	be	AUX
biomedich-739	59	23	conducted	conduct	VERB
biomedich-739	59	24	at	at	ADP
biomedich-739	59	25	the	the	DET
biomedich-739	59	26	pharmacology	pharmacology	NOUN
biomedich-739	59	27	laboratory	laboratory	NOUN
biomedich-739	59	28	of	of	ADP
biomedich-739	59	29	the	the	DET
biomedich-739	59	30	faculty	faculty	NOUN
biomedich-739	59	31	of	of	ADP
biomedich-739	59	32	medicine	medicine	NOUN
biomedich-739	59	33	,	,	PUNCT
biomedich-739	59	34	university	university	NOUN
biomedich-739	59	35	of	of	ADP
biomedich-739	59	36	muhamamdiyah	muhamamdiyah	NOUN
biomedich-739	59	37	surakarta	surakarta	NOUN
biomedich-739	59	38	.	.	PUNCT
biomedich-739	60	1	measurement	measurement	NOUN
biomedich-739	60	2	of	of	ADP
biomedich-739	60	3	col1a1	col1a1	NOUN
biomedich-739	60	4	expression	expression	NOUN
biomedich-739	60	5	used	use	VERB
biomedich-739	60	6	the	the	DET
biomedich-739	60	7	real	real	ADJ
biomedich-739	60	8	-	-	PUNCT
biomedich-739	60	9	time	time	NOUN
biomedich-739	60	10	pcr	pcr	NOUN
biomedich-739	60	11	technique	technique	NOUN
biomedich-739	60	12	at	at	ADP
biomedich-739	60	13	the	the	DET
biomedich-739	60	14	integrated	integrate	VERB
biomedich-739	60	15	research	research	NOUN
biomedich-739	60	16	laboratory	laboratory	NOUN
biomedich-739	60	17	of	of	ADP
biomedich-739	60	18	the	the	DET
biomedich-739	60	19	faculty	faculty	NOUN
biomedich-739	60	20	of	of	ADP
biomedich-739	60	21	medicine	medicine	NOUN
biomedich-739	60	22	,	,	PUNCT
biomedich-739	60	23	public	public	ADJ
biomedich-739	60	24	health	health	NOUN
biomedich-739	60	25	,	,	PUNCT
biomedich-739	60	26	and	and	CCONJ
biomedich-739	60	27	nursing	nursing	NOUN
biomedich-739	60	28	,	,	PUNCT
biomedich-739	60	29	universitas	universita	NOUN
biomedich-739	60	30	gadjah	gadjah	PROPN
biomedich-739	60	31	mada	mada	PROPN
biomedich-739	60	32	,	,	PUNCT
biomedich-739	60	33	yogyakarta	yogyakarta	PROPN
biomedich-739	60	34	.	.	PUNCT
biomedich-739	61	1	procedures	procedure	NOUN
biomedich-739	61	2	extract	extract	VERB
biomedich-739	61	3	preparation	preparation	NOUN
biomedich-739	61	4	the	the	DET
biomedich-739	61	5	symplisia	symplisia	PROPN
biomedich-739	61	6	of	of	ADP
biomedich-739	61	7	cat	cat	NOUN
biomedich-739	61	8	whisker	whisker	NOUN
biomedich-739	61	9	leaves	leave	NOUN
biomedich-739	61	10	(	(	PUNCT
biomedich-739	61	11	ortosiphon	ortosiphon	ADJ
biomedich-739	61	12	aristatus	aristatus	NOUN
biomedich-739	61	13	)	)	PUNCT
biomedich-739	61	14	was	be	AUX
biomedich-739	61	15	obtained	obtain	VERB
biomedich-739	61	16	from	from	ADP
biomedich-739	61	17	b2p2toot	b2p2toot	NUM
biomedich-739	61	18	(	(	PUNCT
biomedich-739	61	19	center	center	NOUN
biomedich-739	61	20	for	for	ADP
biomedich-739	61	21	research	research	NOUN
biomedich-739	61	22	and	and	CCONJ
biomedich-739	61	23	development	development	NOUN
biomedich-739	61	24	of	of	ADP
biomedich-739	61	25	medicinal	medicinal	ADJ
biomedich-739	61	26	plants	plant	NOUN
biomedich-739	61	27	and	and	CCONJ
biomedich-739	61	28	traditional	traditional	ADJ
biomedich-739	61	29	medicine	medicine	NOUN
biomedich-739	61	30	)	)	PUNCT
biomedich-739	61	31	tawangmangu	tawangmangu	NOUN
biomedich-739	61	32	,	,	PUNCT
biomedich-739	61	33	karanganyar	karanganyar	PROPN
biomedich-739	61	34	,	,	PUNCT
biomedich-739	61	35	central	central	ADJ
biomedich-739	61	36	java	java	NOUN
biomedich-739	61	37	and	and	CCONJ
biomedich-739	61	38	the	the	DET
biomedich-739	61	39	determination	determination	NOUN
biomedich-739	61	40	was	be	AUX
biomedich-739	61	41	obtained	obtain	VERB
biomedich-739	61	42	from	from	ADP
biomedich-739	61	43	the	the	DET
biomedich-739	61	44	tawangmangu	tawangmangu	PROPN
biomedich-739	61	45	health	health	NOUN
biomedich-739	61	46	service	service	NOUN
biomedich-739	61	47	upf	upf	PROPN
biomedich-739	61	48	laboratory	laboratory	NOUN
biomedich-739	61	49	.	.	PUNCT
biomedich-739	62	1	symplisia	symplisia	PROPN
biomedich-739	62	2	is	be	AUX
biomedich-739	62	3	then	then	ADV
biomedich-739	62	4	put	put	VERB
biomedich-739	62	5	into	into	ADP
biomedich-739	62	6	a	a	DET
biomedich-739	62	7	maceration	maceration	NOUN
biomedich-739	62	8	pot	pot	NOUN
biomedich-739	62	9	then	then	ADV
biomedich-739	62	10	soaked	soak	VERB
biomedich-739	62	11	using	use	VERB
biomedich-739	62	12	70	70	NUM
biomedich-739	62	13	%	%	NOUN
biomedich-739	62	14	ethanol	ethanol	NOUN
biomedich-739	62	15	,	,	PUNCT
biomedich-739	62	16	stirred	stir	VERB
biomedich-739	62	17	for	for	ADP
biomedich-739	62	18	1	1	NUM
biomedich-739	62	19	hour	hour	NOUN
biomedich-739	62	20	per	per	ADP
biomedich-739	62	21	day	day	NOUN
biomedich-739	62	22	for	for	ADP
biomedich-739	62	23	5	5	NUM
biomedich-739	62	24	days	day	NOUN
biomedich-739	62	25	.	.	PUNCT
biomedich-739	63	1	the	the	DET
biomedich-739	63	2	results	result	NOUN
biomedich-739	63	3	of	of	ADP
biomedich-739	63	4	the	the	DET
biomedich-739	63	5	soak	soak	NOUN
biomedich-739	63	6	are	be	AUX
biomedich-739	63	7	filtered	filter	VERB
biomedich-739	63	8	with	with	ADP
biomedich-739	63	9	a	a	DET
biomedich-739	63	10	filter	filter	NOUN
biomedich-739	63	11	cloth	cloth	NOUN
biomedich-739	63	12	.	.	PUNCT
biomedich-739	64	1	then	then	ADV
biomedich-739	64	2	it	it	PRON
biomedich-739	64	3	is	be	AUX
biomedich-739	64	4	evaporated	evaporate	VERB
biomedich-739	64	5	with	with	ADP
biomedich-739	64	6	an	an	DET
biomedich-739	64	7	evaporator	evaporator	NOUN
biomedich-739	64	8	to	to	PART
biomedich-739	64	9	produce	produce	VERB
biomedich-739	64	10	a	a	DET
biomedich-739	64	11	viscous	viscous	ADJ
biomedich-739	64	12	extract	extract	NOUN
biomedich-739	64	13	.	.	PUNCT
biomedich-739	65	1	the	the	DET
biomedich-739	65	2	next	next	ADJ
biomedich-739	65	3	step	step	NOUN
biomedich-739	65	4	is	be	AUX
biomedich-739	65	5	the	the	DET
biomedich-739	65	6	calculation	calculation	NOUN
biomedich-739	65	7	of	of	ADP
biomedich-739	65	8	the	the	DET
biomedich-739	65	9	dosage	dosage	NOUN
biomedich-739	65	10	and	and	CCONJ
biomedich-739	65	11	the	the	DET
biomedich-739	65	12	manufacture	manufacture	NOUN
biomedich-739	65	13	of	of	ADP
biomedich-739	65	14	the	the	DET
biomedich-739	65	15	stock	stock	NOUN
biomedich-739	65	16	solution	solution	NOUN
biomedich-739	65	17	.	.	PUNCT
biomedich-739	66	1	animal	animal	NOUN
biomedich-739	66	2	preparation	preparation	NOUN
biomedich-739	66	3	and	and	CCONJ
biomedich-739	66	4	diabetes	diabetes	NOUN
biomedich-739	66	5	induction	induction	NOUN
biomedich-739	66	6	the	the	DET
biomedich-739	66	7	experimental	experimental	ADJ
biomedich-739	66	8	animal	animal	NOUN
biomedich-739	66	9	was	be	AUX
biomedich-739	66	10	a	a	DET
biomedich-739	66	11	male	male	ADJ
biomedich-739	66	12	rattus	rattus	NOUN
biomedich-739	66	13	norvegicus	norvegicus	NOUN
biomedich-739	66	14	of	of	ADP
biomedich-739	66	15	the	the	DET
biomedich-739	66	16	wistar	wistar	PROPN
biomedich-739	66	17	strain	strain	NOUN
biomedich-739	66	18	obtained	obtain	VERB
biomedich-739	66	19	from	from	ADP
biomedich-739	66	20	the	the	DET
biomedich-739	66	21	pharmacology	pharmacology	NOUN
biomedich-739	66	22	laboratory	laboratory	NOUN
biomedich-739	66	23	,	,	PUNCT
biomedich-739	66	24	faculty	faculty	NOUN
biomedich-739	66	25	of	of	ADP
biomedich-739	66	26	medicine	medicine	NOUN
biomedich-739	66	27	,	,	PUNCT
biomedich-739	66	28	universitas	universita	NOUN
biomedich-739	66	29	muhammadiyah	muhammadiyah	ADP
biomedich-739	66	30	surakarta	surakarta	NOUN
biomedich-739	66	31	.	.	PUNCT
biomedich-739	67	1	the	the	DET
biomedich-739	67	2	inclusion	inclusion	NOUN
biomedich-739	67	3	criteria	criterion	NOUN
biomedich-739	67	4	were	be	AUX
biomedich-739	67	5	healthy	healthy	ADJ
biomedich-739	67	6	rats	rat	NOUN
biomedich-739	67	7	(	(	PUNCT
biomedich-739	67	8	normal	normal	ADJ
biomedich-739	67	9	activity	activity	NOUN
biomedich-739	67	10	)	)	PUNCT
biomedich-739	67	11	,	,	PUNCT
biomedich-739	67	12	body	body	NOUN
biomedich-739	67	13	weight	weight	NOUN
biomedich-739	67	14	150	150	NUM
biomedich-739	67	15	-	-	SYM
biomedich-739	67	16	200	200	NUM
biomedich-739	67	17	grams	gram	NOUN
biomedich-739	67	18	,	,	PUNCT
biomedich-739	67	19	2	2	NUM
biomedich-739	67	20	-	-	SYM
biomedich-739	67	21	3	3	NUM
biomedich-739	67	22	months	month	NOUN
biomedich-739	67	23	old	old	ADJ
biomedich-739	67	24	.	.	PUNCT
biomedich-739	68	1	the	the	DET
biomedich-739	68	2	mice	mouse	NOUN
biomedich-739	68	3	were	be	AUX
biomedich-739	68	4	fasted	fast	VERB
biomedich-739	68	5	for	for	ADP
biomedich-739	68	6	8	8	NUM
biomedich-739	68	7	hours	hour	NOUN
biomedich-739	68	8	then	then	ADV
biomedich-739	68	9	divided	divide	VERB
biomedich-739	68	10	into	into	ADP
biomedich-739	68	11	6	6	NUM
biomedich-739	68	12	groups	group	NOUN
biomedich-739	68	13	(	(	PUNCT
biomedich-739	68	14	g	g	NOUN
biomedich-739	68	15	)	)	PUNCT
biomedich-739	68	16	randomly	randomly	ADV
biomedich-739	68	17	and	and	CCONJ
biomedich-739	68	18	blood	blood	NOUN
biomedich-739	68	19	sugar	sugar	NOUN
biomedich-739	68	20	measurements	measurement	NOUN
biomedich-739	68	21	were	be	AUX
biomedich-739	68	22	taken	take	VERB
biomedich-739	68	23	(	(	PUNCT
biomedich-739	68	24	g1	g1	NOUN
biomedich-739	68	25	:	:	PUNCT
biomedich-739	68	26	non	non	ADJ
biomedich-739	68	27	diabetic	diabetic	ADJ
biomedich-739	68	28	negative	negative	ADJ
biomedich-739	68	29	control	control	NOUN
biomedich-739	68	30	,	,	PUNCT
biomedich-739	68	31	g2	g2	PROPN
biomedich-739	68	32	:	:	PUNCT
biomedich-739	68	33	diabetic	diabetic	ADJ
biomedich-739	68	34	negative	negative	ADJ
biomedich-739	68	35	control	control	NOUN
biomedich-739	68	36	,	,	PUNCT
biomedich-739	68	37	g3	g3	PROPN
biomedich-739	68	38	:	:	PUNCT
biomedich-739	68	39	metformin	metformin	NOUN
biomedich-739	68	40	,	,	PUNCT
biomedich-739	68	41	g4	g4	NOUN
biomedich-739	68	42	:	:	PUNCT
biomedich-739	68	43	ortosiphon	ortosiphon	ADJ
biomedich-739	68	44	aristatus	aristatus	NOUN
biomedich-739	68	45	(	(	PUNCT
biomedich-739	68	46	cat	cat	NOUN
biomedich-739	68	47	whisker	whisker	NOUN
biomedich-739	68	48	)	)	PUNCT
biomedich-739	68	49	extract	extract	NOUN
biomedich-739	68	50	dose	dose	VERB
biomedich-739	68	51	100mg	100mg	PROPN
biomedich-739	68	52	/	/	SYM
biomedich-739	68	53	kgbw	kgbw	PROPN
biomedich-739	68	54	,	,	PUNCT
biomedich-739	68	55	g5	g5	PROPN
biomedich-739	68	56	:	:	PUNCT
biomedich-739	68	57	ortosiphon	ortosiphon	ADJ
biomedich-739	68	58	aristatus	aristatus	PROPN
biomedich-739	68	59	extract	extract	NOUN
biomedich-739	68	60	dose	dose	VERB
biomedich-739	68	61	200mg	200mg	PROPN
biomedich-739	68	62	/	/	SYM
biomedich-739	68	63	kgbw	kgbw	PROPN
biomedich-739	68	64	,	,	PUNCT
biomedich-739	68	65	and	and	CCONJ
biomedich-739	68	66	ortosiphon	ortosiphon	ADJ
biomedich-739	68	67	aristatus	aristatus	NOUN
biomedich-739	68	68	extract	extract	NOUN
biomedich-739	68	69	dose	dose	VERB
biomedich-739	68	70	400mg	400mg	PROPN
biomedich-739	68	71	/	/	SYM
biomedich-739	68	72	kgbw	kgbw	PROPN
biomedich-739	68	73	.	.	PUNCT
biomedich-739	69	1	rats	rat	NOUN
biomedich-739	69	2	in	in	ADP
biomedich-739	69	3	the	the	DET
biomedich-739	69	4	g2	g2	PROPN
biomedich-739	69	5	-	-	PUNCT
biomedich-739	69	6	g6	g6	ADJ
biomedich-739	69	7	group	group	NOUN
biomedich-739	69	8	were	be	AUX
biomedich-739	69	9	induced	induce	VERB
biomedich-739	69	10	by	by	ADP
biomedich-739	69	11	hyperglycemic	hyperglycemic	ADJ
biomedich-739	69	12	agent	agent	NOUN
biomedich-739	69	13	using	use	VERB
biomedich-739	69	14	nicotinamide	nicotinamide	NOUN
biomedich-739	69	15	(	(	PUNCT
biomedich-739	69	16	nta	nta	PROPN
biomedich-739	69	17	)	)	PUNCT
biomedich-739	69	18	injection	injection	NOUN
biomedich-739	69	19	230	230	NUM
biomedich-739	69	20	mg	mg	PROPN
biomedich-739	69	21	/	/	SYM
biomedich-739	69	22	kgbb	kgbb	NOUN
biomedich-739	69	23	as	as	ADP
biomedich-739	69	24	pancreatic	pancreatic	ADJ
biomedich-739	69	25	protector	protector	NOUN
biomedich-739	69	26	and	and	CCONJ
biomedich-739	69	27	streptozotocin	streptozotocin	PROPN
biomedich-739	69	28	(	(	PUNCT
biomedich-739	69	29	stz	stz	NOUN
biomedich-739	69	30	)	)	PUNCT
biomedich-739	69	31	65	65	NUM
biomedich-739	69	32	mg	mg	NUM
biomedich-739	69	33	/	/	SYM
biomedich-739	69	34	kgbb	kgbb	NOUN
biomedich-739	69	35	intraperitonially	intraperitonially	ADV
biomedich-739	69	36	and	and	CCONJ
biomedich-739	69	37	were	be	AUX
biomedich-739	69	38	given	give	VERB
biomedich-739	69	39	standard	standard	ADJ
biomedich-739	69	40	feed	feed	NOUN
biomedich-739	69	41	and	and	CCONJ
biomedich-739	69	42	drinking	drinking	NOUN
biomedich-739	69	43	water	water	NOUN
biomedich-739	69	44	every	every	DET
biomedich-739	69	45	day	day	NOUN
biomedich-739	69	46	.	.	PUNCT
biomedich-739	70	1	aisyah	aisyah	PROPN
biomedich-739	70	2	et	et	PROPN
biomedich-739	70	3	al	al	PROPN
biomedich-739	70	4	.	.	PROPN
biomedich-739	70	5	–	–	PUNCT
biomedich-739	70	6	effect	effect	NOUN
biomedich-739	70	7	of	of	ADP
biomedich-739	70	8	ortosiphon	ortosiphon	ADJ
biomedich-739	70	9	aristatus	aristatus	NOUN
biomedich-739	70	10	on	on	ADP
biomedich-739	70	11	improving	improve	VERB
biomedich-739	70	12	col1a1	col1a1	NOUN
biomedich-739	70	13	expression	expression	NOUN
biomedich-739	70	14	359	359	NUM
biomedich-739	70	15	blood	blood	NOUN
biomedich-739	70	16	sugar	sugar	NOUN
biomedich-739	70	17	levels	level	NOUN
biomedich-739	70	18	measurement	measurement	VERB
biomedich-739	70	19	blood	blood	NOUN
biomedich-739	70	20	sugar	sugar	NOUN
biomedich-739	70	21	level	level	NOUN
biomedich-739	70	22	measurements	measurement	NOUN
biomedich-739	70	23	were	be	AUX
biomedich-739	70	24	carried	carry	VERB
biomedich-739	70	25	out	out	ADP
biomedich-739	70	26	on	on	ADP
biomedich-739	70	27	day	day	NOUN
biomedich-739	70	28	0	0	NUM
biomedich-739	70	29	,	,	PUNCT
biomedich-739	70	30	day	day	NOUN
biomedich-739	70	31	4	4	NUM
biomedich-739	70	32	after	after	ADP
biomedich-739	70	33	stz	stz	NOUN
biomedich-739	70	34	and	and	CCONJ
biomedich-739	70	35	nta	nta	NOUN
biomedich-739	70	36	induction	induction	NOUN
biomedich-739	70	37	,	,	PUNCT
biomedich-739	70	38	and	and	CCONJ
biomedich-739	70	39	day	day	NOUN
biomedich-739	70	40	14	14	NUM
biomedich-739	70	41	.	.	PUNCT
biomedich-739	71	1	rats	rat	NOUN
biomedich-739	71	2	whose	whose	DET
biomedich-739	71	3	sugar	sugar	NOUN
biomedich-739	71	4	levels	level	NOUN
biomedich-739	71	5	had	have	AUX
biomedich-739	71	6	increased	increase	VERB
biomedich-739	71	7	in	in	ADP
biomedich-739	71	8	the	the	DET
biomedich-739	71	9	g2	g2	PROPN
biomedich-739	71	10	-	-	PUNCT
biomedich-739	71	11	g6	g6	ADJ
biomedich-739	71	12	group	group	NOUN
biomedich-739	71	13	were	be	AUX
biomedich-739	71	14	given	give	VERB
biomedich-739	71	15	cat	cat	NOUN
biomedich-739	71	16	whisker	whisker	NOUN
biomedich-739	71	17	leaf	leaf	NOUN
biomedich-739	71	18	extract	extract	NOUN
biomedich-739	71	19	treatment	treatment	NOUN
biomedich-739	71	20	for	for	ADP
biomedich-739	71	21	14	14	NUM
biomedich-739	71	22	days	day	NOUN
biomedich-739	71	23	orally	orally	ADV
biomedich-739	71	24	.	.	PUNCT
biomedich-739	72	1	following	follow	VERB
biomedich-739	72	2	a	a	DET
biomedich-739	72	3	14	14	NUM
biomedich-739	72	4	-	-	PUNCT
biomedich-739	72	5	day	day	NOUN
biomedich-739	72	6	period	period	NOUN
biomedich-739	72	7	,	,	PUNCT
biomedich-739	72	8	blood	blood	NOUN
biomedich-739	72	9	glucose	glucose	NOUN
biomedich-739	72	10	levels	level	NOUN
biomedich-739	72	11	were	be	AUX
biomedich-739	72	12	evaluated	evaluate	VERB
biomedich-739	72	13	,	,	PUNCT
biomedich-739	72	14	and	and	CCONJ
biomedich-739	72	15	the	the	DET
biomedich-739	72	16	procedure	procedure	NOUN
biomedich-739	72	17	was	be	AUX
biomedich-739	72	18	completed	complete	VERB
biomedich-739	72	19	for	for	ADP
biomedich-739	72	20	the	the	DET
biomedich-739	72	21	collection	collection	NOUN
biomedich-739	72	22	of	of	ADP
biomedich-739	72	23	adipose	adipose	ADJ
biomedich-739	72	24	tissue	tissue	NOUN
biomedich-739	72	25	.	.	PUNCT
biomedich-739	73	1	measurement	measurement	NOUN
biomedich-739	73	2	of	of	ADP
biomedich-739	73	3	col1a1	col1a1	NOUN
biomedich-739	73	4	expression	expression	NOUN
biomedich-739	73	5	approximately	approximately	ADV
biomedich-739	73	6	30	30	NUM
biomedich-739	73	7	mg	mg	NOUN
biomedich-739	73	8	of	of	ADP
biomedich-739	73	9	rat	rat	NOUN
biomedich-739	73	10	adipose	adipose	ADJ
biomedich-739	73	11	tissue	tissue	NOUN
biomedich-739	73	12	was	be	AUX
biomedich-739	73	13	inserted	insert	VERB
biomedich-739	73	14	into	into	ADP
biomedich-739	73	15	an	an	DET
biomedich-739	73	16	rna	rna	NOUN
biomedich-739	73	17	stabilizing	stabilizing	NOUN
biomedich-739	73	18	solution	solution	NOUN
biomedich-739	73	19	for	for	ADP
biomedich-739	73	20	rna	rna	NOUN
biomedich-739	73	21	extraction	extraction	NOUN
biomedich-739	73	22	using	use	VERB
biomedich-739	73	23	phenol	phenol	ADJ
biomedich-739	73	24	chloroform	chloroform	NOUN
biomedich-739	73	25	and	and	CCONJ
biomedich-739	73	26	cdna	cdna	PROPN
biomedich-739	73	27	synthesis	synthesis	NOUN
biomedich-739	73	28	according	accord	VERB
biomedich-739	73	29	to	to	ADP
biomedich-739	73	30	the	the	DET
biomedich-739	73	31	protocol	protocol	NOUN
biomedich-739	73	32	smobio	smobio	PROPN
biomedich-739	73	33	excel	excel	PROPN
biomedich-739	73	34	rt	rt	PROPN
biomedich-739	73	35	kit	kit	PROPN
biomedich-739	73	36	ii	ii	PROPN
biomedich-739	73	37	rp1400	rp1400	PROPN
biomedich-739	73	38	.	.	PUNCT
biomedich-739	74	1	col1a1	col1a1	NOUN
biomedich-739	74	2	gene	gene	NOUN
biomedich-739	74	3	expression	expression	NOUN
biomedich-739	74	4	was	be	AUX
biomedich-739	74	5	measured	measure	VERB
biomedich-739	74	6	using	use	VERB
biomedich-739	74	7	real	real	ADJ
biomedich-739	74	8	-	-	PUNCT
biomedich-739	74	9	time	time	NOUN
biomedich-739	74	10	pcr	pcr	NOUN
biomedich-739	74	11	according	accord	VERB
biomedich-739	74	12	to	to	ADP
biomedich-739	74	13	the	the	DET
biomedich-739	74	14	protocol	protocol	NOUN
biomedich-739	74	15	of	of	ADP
biomedich-739	74	16	the	the	DET
biomedich-739	74	17	sensifast	sensifast	PROPN
biomedich-739	74	18	bioline	bioline	PROPN
biomedich-739	74	19	sybr	sybr	PROPN
biomedich-739	74	20	green	green	PROPN
biomedich-739	74	21	kit	kit	NOUN
biomedich-739	74	22	with	with	ADP
biomedich-739	74	23	a	a	DET
biomedich-739	74	24	specific	specific	ADJ
biomedich-739	74	25	primer	primer	NOUN
biomedich-739	74	26	.	.	PUNCT
biomedich-739	75	1	housekeeping	housekeep	VERB
biomedich-739	75	2	gene	gene	NOUN
biomedich-739	75	3	β	β	NOUN
biomedich-739	75	4	-	-	NOUN
biomedich-739	75	5	actin	actin	NOUN
biomedich-739	75	6	was	be	AUX
biomedich-739	75	7	used	use	VERB
biomedich-739	75	8	as	as	ADP
biomedich-739	75	9	an	an	DET
biomedich-739	75	10	internal	internal	ADJ
biomedich-739	75	11	control	control	NOUN
biomedich-739	75	12	.	.	PUNCT
biomedich-739	76	1	col1a1	col1a1	NOUN
biomedich-739	76	2	expression	expression	NOUN
biomedich-739	76	3	was	be	AUX
biomedich-739	76	4	determined	determine	VERB
biomedich-739	76	5	by	by	ADP
biomedich-739	76	6	measuring	measure	VERB
biomedich-739	76	7	the	the	DET
biomedich-739	76	8	cycle	cycle	NOUN
biomedich-739	76	9	of	of	ADP
biomedich-739	76	10	tresh	tresh	NOUN
biomedich-739	76	11	-	-	PUNCT
biomedich-739	76	12	hold	hold	NOUN
biomedich-739	76	13	(	(	PUNCT
biomedich-739	76	14	ct	ct	NOUN
biomedich-739	76	15	)	)	PUNCT
biomedich-739	76	16	ratio	ratio	NOUN
biomedich-739	76	17	of	of	ADP
biomedich-739	76	18	the	the	DET
biomedich-739	76	19	col1a1	col1a1	NOUN
biomedich-739	76	20	gene	gene	NOUN
biomedich-739	76	21	to	to	ADP
biomedich-739	76	22	the	the	DET
biomedich-739	76	23	internal	internal	ADJ
biomedich-739	76	24	gene	gene	NOUN
biomedich-739	76	25	β	β	NOUN
biomedich-739	76	26	-	-	NOUN
biomedich-739	76	27	actin	actin	NOUN
biomedich-739	76	28	.	.	PUNCT
biomedich-739	76	29	table	table	NOUN
biomedich-739	76	30	1	1	NUM
biomedich-739	76	31	.	.	PUNCT
biomedich-739	76	32	primer	primer	NOUN
biomedich-739	76	33	base	base	NOUN
biomedich-739	76	34	sequence	sequence	NOUN
biomedich-739	76	35	of	of	ADP
biomedich-739	76	36	col1a1	col1a1	NOUN
biomedich-739	76	37	and	and	CCONJ
biomedich-739	76	38	β	β	NOUN
biomedich-739	76	39	-	-	ADJ
biomedich-739	76	40	actin	actin	NOUN
biomedich-739	76	41	genes	gene	NOUN
biomedich-739	76	42	.	.	PUNCT
biomedich-739	77	1	forward	forward	ADJ
biomedich-739	77	2	primer	primer	NOUN
biomedich-739	77	3	reverse	reverse	NOUN
biomedich-739	77	4	primer	primer	NOUN
biomedich-739	77	5	col1a1	col1a1	PROPN
biomedich-739	77	6	tggcaagaacggagatga	tggcaagaacggagatga	PROPN
biomedich-739	77	7	agctgttccaggcaatcc	agctgttccaggcaatcc	ADJ
biomedich-739	77	8	β	β	NOUN
biomedich-739	77	9	-	-	PUNCT
biomedich-739	77	10	actin	actin	ADJ
biomedich-739	77	11	ctatcggcaatgagcggttcc	ctatcggcaatgagcggttcc	PROPN
biomedich-739	77	12	tgtgttggcatagaggtctttacg	tgtgttggcatagaggtctttacg	PROPN
biomedich-739	77	13	data	datum	NOUN
biomedich-739	77	14	analysis	analysis	NOUN
biomedich-739	77	15	the	the	DET
biomedich-739	77	16	data	datum	NOUN
biomedich-739	77	17	on	on	ADP
biomedich-739	77	18	blood	blood	NOUN
biomedich-739	77	19	sugar	sugar	NOUN
biomedich-739	77	20	levels	level	NOUN
biomedich-739	77	21	and	and	CCONJ
biomedich-739	77	22	col1a1	col1a1	NOUN
biomedich-739	77	23	expression	expression	NOUN
biomedich-739	77	24	obtained	obtain	VERB
biomedich-739	77	25	were	be	AUX
biomedich-739	77	26	statistically	statistically	ADV
biomedich-739	77	27	processed	process	VERB
biomedich-739	77	28	by	by	ADP
biomedich-739	77	29	the	the	DET
biomedich-739	77	30	kruskall	kruskall	PROPN
biomedich-739	77	31	wallis	wallis	PROPN
biomedich-739	77	32	non	non	ADJ
biomedich-739	77	33	-	-	ADJ
biomedich-739	77	34	paramteric	paramteric	ADJ
biomedich-739	77	35	test	test	NOUN
biomedich-739	77	36	and	and	CCONJ
biomedich-739	77	37	the	the	DET
biomedich-739	77	38	spearman	spearman	NOUN
biomedich-739	77	39	's	's	PART
biomedich-739	77	40	rho	rho	ADJ
biomedich-739	77	41	correlation	correlation	NOUN
biomedich-739	77	42	test	test	NOUN
biomedich-739	77	43	.	.	PUNCT
biomedich-739	78	1	results	result	NOUN
biomedich-739	78	2	and	and	CCONJ
biomedich-739	78	3	discussion	discussion	NOUN
biomedich-739	78	4	based	base	VERB
biomedich-739	78	5	on	on	ADP
biomedich-739	78	6	blood	blood	NOUN
biomedich-739	78	7	sugar	sugar	NOUN
biomedich-739	78	8	level	level	NOUN
biomedich-739	78	9	data	datum	NOUN
biomedich-739	78	10	,	,	PUNCT
biomedich-739	78	11	there	there	PRON
biomedich-739	78	12	was	be	VERB
biomedich-739	78	13	an	an	DET
biomedich-739	78	14	increase	increase	NOUN
biomedich-739	78	15	in	in	ADP
biomedich-739	78	16	blood	blood	NOUN
biomedich-739	78	17	sugar	sugar	NOUN
biomedich-739	78	18	levels	level	NOUN
biomedich-739	78	19	after	after	ADP
biomedich-739	78	20	induction	induction	NOUN
biomedich-739	78	21	of	of	ADP
biomedich-739	78	22	streptozotocin	streptozotocin	PROPN
biomedich-739	78	23	and	and	CCONJ
biomedich-739	78	24	nicotinamide	nicotinamide	NOUN
biomedich-739	78	25	in	in	ADP
biomedich-739	78	26	all	all	DET
biomedich-739	78	27	groups	group	NOUN
biomedich-739	78	28	(	(	PUNCT
biomedich-739	78	29	pre	pre	ADJ
biomedich-739	78	30	-	-	NOUN
biomedich-739	78	31	test	test	NOUN
biomedich-739	78	32	)	)	PUNCT
biomedich-739	78	33	and	and	CCONJ
biomedich-739	78	34	there	there	PRON
biomedich-739	78	35	was	be	VERB
biomedich-739	78	36	a	a	DET
biomedich-739	78	37	decrease	decrease	NOUN
biomedich-739	78	38	in	in	ADP
biomedich-739	78	39	blood	blood	NOUN
biomedich-739	78	40	sugar	sugar	NOUN
biomedich-739	78	41	levels	level	NOUN
biomedich-739	78	42	after	after	ADP
biomedich-739	78	43	administration	administration	NOUN
biomedich-739	78	44	of	of	ADP
biomedich-739	78	45	ortosiphon	ortosiphon	ADJ
biomedich-739	78	46	aristatus	aristatus	PROPN
biomedich-739	78	47	leaf	leaf	NOUN
biomedich-739	78	48	extract	extract	NOUN
biomedich-739	78	49	(	(	PUNCT
biomedich-739	78	50	post	post	NOUN
biomedich-739	78	51	-	-	NOUN
biomedich-739	78	52	test	test	NOUN
biomedich-739	78	53	)	)	PUNCT
biomedich-739	78	54	.	.	PUNCT
biomedich-739	79	1	because	because	SCONJ
biomedich-739	79	2	the	the	DET
biomedich-739	79	3	pretest	pret	ADJ
biomedich-739	79	4	data	data	NOUN
biomedich-739	79	5	is	be	AUX
biomedich-739	79	6	not	not	PART
biomedich-739	79	7	homogeneous	homogeneous	ADJ
biomedich-739	79	8	,	,	PUNCT
biomedich-739	79	9	the	the	DET
biomedich-739	79	10	data	datum	NOUN
biomedich-739	79	11	on	on	ADP
biomedich-739	79	12	the	the	DET
biomedich-739	79	13	difference	difference	NOUN
biomedich-739	79	14	in	in	ADP
biomedich-739	79	15	blood	blood	NOUN
biomedich-739	79	16	sugar	sugar	NOUN
biomedich-739	79	17	levels	level	NOUN
biomedich-739	79	18	of	of	ADP
biomedich-739	79	19	the	the	DET
biomedich-739	79	20	pretest	pretest	NOUN
biomedich-739	79	21	and	and	CCONJ
biomedich-739	79	22	the	the	DET
biomedich-739	79	23	postest	post	ADJ
biomedich-739	79	24	is	be	AUX
biomedich-739	79	25	used	use	VERB
biomedich-739	79	26	for	for	ADP
biomedich-739	79	27	analysis	analysis	NOUN
biomedich-739	79	28	as	as	SCONJ
biomedich-739	79	29	presented	present	VERB
biomedich-739	79	30	in	in	ADP
biomedich-739	79	31	table	table	NOUN
biomedich-739	79	32	1	1	NUM
biomedich-739	79	33	.	.	PUNCT
biomedich-739	80	1	as	as	ADP
biomedich-739	80	2	for	for	ADP
biomedich-739	80	3	the	the	DET
biomedich-739	80	4	col1a1	col1a1	NOUN
biomedich-739	80	5	expression	expression	NOUN
biomedich-739	80	6	data	datum	NOUN
biomedich-739	80	7	,	,	PUNCT
biomedich-739	80	8	there	there	PRON
biomedich-739	80	9	was	be	VERB
biomedich-739	80	10	no	no	DET
biomedich-739	80	11	difference	difference	NOUN
biomedich-739	80	12	in	in	ADP
biomedich-739	80	13	expression	expression	NOUN
biomedich-739	80	14	between	between	ADP
biomedich-739	80	15	groups	group	NOUN
biomedich-739	80	16	with	with	ADP
biomedich-739	80	17	a	a	DET
biomedich-739	80	18	value	value	NOUN
biomedich-739	80	19	of	of	ADP
biomedich-739	80	20	p>0.05	p>0.05	PROPN
biomedich-739	80	21	.	.	PUNCT
biomedich-739	81	1	table	table	NOUN
biomedich-739	81	2	2	2	NUM
biomedich-739	81	3	.	.	X
biomedich-739	81	4	result	result	NOUN
biomedich-739	81	5	of	of	ADP
biomedich-739	81	6	blood	blood	NOUN
biomedich-739	81	7	glucose	glucose	NOUN
biomedich-739	81	8	and	and	CCONJ
biomedich-739	81	9	col1a1	col1a1	NOUN
biomedich-739	81	10	expression	expression	NOUN
biomedich-739	81	11	measurement	measurement	NOUN
biomedich-739	81	12	.	.	PUNCT
biomedich-739	82	1	parameters	parameter	NOUN
biomedich-739	82	2	control	control	VERB
biomedich-739	82	3	(	(	PUNCT
biomedich-739	82	4	-	-	PUNCT
biomedich-739	82	5	)	)	PUNCT
biomedich-739	82	6	non	non	ADJ
biomedich-739	82	7	diabetic	diabetic	ADJ
biomedich-739	82	8	control	control	NOUN
biomedich-739	82	9	(	(	PUNCT
biomedich-739	82	10	)	)	PUNCT
biomedich-739	82	11	diabetic	diabetic	ADJ
biomedich-739	82	12	control	control	NOUN
biomedich-739	82	13	(	(	PUNCT
biomedich-739	82	14	+	+	NOUN
biomedich-739	82	15	)	)	PUNCT
biomedich-739	82	16	group	group	NOUN
biomedich-739	82	17	1	1	NUM
biomedich-739	82	18	(	(	PUNCT
biomedich-739	82	19	100mg	100mg	PROPN
biomedich-739	82	20	/	/	SYM
biomedich-739	82	21	kgbw	kgbw	PROPN
biomedich-739	82	22	)	)	PUNCT
biomedich-739	82	23	group	group	NOUN
biomedich-739	82	24	2	2	NUM
biomedich-739	82	25	(	(	PUNCT
biomedich-739	82	26	200mg	200mg	PROPN
biomedich-739	82	27	/	/	SYM
biomedich-739	82	28	kgbw	kgbw	PROPN
biomedich-739	82	29	)	)	PUNCT
biomedich-739	82	30	group	group	NOUN
biomedich-739	82	31	3	3	NUM
biomedich-739	82	32	(	(	PUNCT
biomedich-739	82	33	400mg	400mg	PROPN
biomedich-739	82	34	/	/	SYM
biomedich-739	82	35	kgbw	kgbw	NOUN
biomedich-739	82	36	)	)	PUNCT
biomedich-739	82	37	p	p	NOUN
biomedich-739	82	38	value	value	NOUN
biomedich-739	82	39	blood	blood	NOUN
biomedich-739	82	40	glucose	glucose	NOUN
biomedich-739	82	41	preposttest	prepostt	ADJ
biomedich-739	82	42	difference	difference	NOUN
biomedich-739	82	43	21±19.13	21±19.13	NUM
biomedich-739	82	44	15.33±	15.33±	NUM
biomedich-739	82	45	9.81	9.81	NUM
biomedich-739	82	46	33.67±5.91	33.67±5.91	NUM
biomedich-739	82	47	48.33±	48.33±	NUM
biomedich-739	82	48	20.37	20.37	NUM
biomedich-739	82	49	35.67±	35.67±	NUM
biomedich-739	82	50	12.81	12.81	NUM
biomedich-739	82	51	34±	34±	PROPN
biomedich-739	82	52	30.41	30.41	NUM
biomedich-739	82	53	>	>	PUNCT
biomedich-739	82	54	0.05	0.05	NUM
biomedich-739	82	55	*	*	VERB
biomedich-739	82	56	col1a1	col1a1	NOUN
biomedich-739	82	57	expression	expression	NOUN
biomedich-739	82	58	posttest	postt	ADJ
biomedich-739	82	59	0,2±0,1	0,2±0,1	NUM
biomedich-739	82	60	1,7±0,2	1,7±0,2	NUM
biomedich-739	82	61	0,9±1,3	0,9±1,3	NUM
biomedich-739	83	1	1,3±1,9	1,3±1,9	NUM
biomedich-739	83	2	0,3±0,5	0,3±0,5	NUM
biomedich-739	84	1	1,7±2,9	1,7±2,9	NUM
biomedich-739	84	2	>	>	PUNCT
biomedich-739	84	3	0.05	0.05	NUM
biomedich-739	84	4	*	*	NOUN
biomedich-739	84	5	blood	blood	NOUN
biomedich-739	84	6	glucose	glucose	NOUN
biomedich-739	84	7	&	&	CCONJ
biomedich-739	84	8	col1a1	col1a1	NOUN
biomedich-739	84	9	expression	expression	NOUN
biomedich-739	84	10	>	>	PUNCT
biomedich-739	84	11	0.05	0.05	NUM
biomedich-739	84	12	*	*	NOUN
biomedich-739	84	13	*	*	PUNCT
biomedich-739	85	1	*	*	PUNCT
biomedich-739	85	2	:	:	PUNCT
biomedich-739	85	3	kruskal	kruskal	PROPN
biomedich-739	85	4	wallis	wallis	PROPN
biomedich-739	85	5	test	test	NOUN
biomedich-739	85	6	*	*	PUNCT
biomedich-739	86	1	*	*	PUNCT
biomedich-739	86	2	:	:	PUNCT
biomedich-739	86	3	spearman	spearman	NOUN
biomedich-739	86	4	’s	’s	PART
biomedich-739	86	5	rho	rho	ADJ
biomedich-739	86	6	test	test	NOUN
biomedich-739	86	7	discussion	discussion	NOUN
biomedich-739	86	8	this	this	DET
biomedich-739	86	9	study	study	NOUN
biomedich-739	86	10	showed	show	VERB
biomedich-739	86	11	that	that	SCONJ
biomedich-739	86	12	the	the	DET
biomedich-739	86	13	administration	administration	NOUN
biomedich-739	86	14	of	of	ADP
biomedich-739	86	15	streptozotocin	streptozotocin	PROPN
biomedich-739	86	16	at	at	ADP
biomedich-739	86	17	65	65	NUM
biomedich-739	86	18	mg	mg	PROPN
biomedich-739	86	19	/	/	SYM
biomedich-739	86	20	kg	kg	PROPN
biomedich-739	86	21	body	body	NOUN
biomedich-739	86	22	weight	weight	NOUN
biomedich-739	86	23	and	and	CCONJ
biomedich-739	86	24	nta	nta	NOUN
biomedich-739	86	25	at	at	ADP
biomedich-739	86	26	230	230	NUM
biomedich-739	86	27	mg	mg	PROPN
biomedich-739	86	28	/	/	SYM
biomedich-739	86	29	kg	kg	PROPN
biomedich-739	86	30	body	body	NOUN
biomedich-739	86	31	weight	weight	NOUN
biomedich-739	86	32	effectively	effectively	ADV
biomedich-739	86	33	elevated	elevate	VERB
biomedich-739	86	34	blood	blood	NOUN
biomedich-739	86	35	glucose	glucose	NOUN
biomedich-739	86	36	levels	level	NOUN
biomedich-739	86	37	by	by	ADP
biomedich-739	86	38	the	the	DET
biomedich-739	86	39	19th	19th	ADJ
biomedich-739	86	40	day	day	NOUN
biomedich-739	86	41	post	post	ADJ
biomedich-739	86	42	-	-	NOUN
biomedich-739	86	43	induction	induction	NOUN
biomedich-739	86	44	,	,	PUNCT
biomedich-739	86	45	aligning	align	VERB
biomedich-739	86	46	with	with	ADP
biomedich-739	86	47	the	the	DET
biomedich-739	86	48	mechanisms	mechanism	NOUN
biomedich-739	86	49	associated	associate	VERB
biomedich-739	86	50	with	with	ADP
biomedich-739	86	51	type	type	NOUN
biomedich-739	86	52	2	2	NUM
biomedich-739	86	53	diabetes	diabetes	NOUN
biomedich-739	86	54	(	(	PUNCT
biomedich-739	86	55	t2d	t2d	NOUN
biomedich-739	86	56	)	)	PUNCT
biomedich-739	86	57	.	.	PUNCT
biomedich-739	87	1	on	on	ADP
biomedich-739	87	2	the	the	DET
biomedich-739	87	3	19th	19th	ADJ
biomedich-739	87	4	day	day	NOUN
biomedich-739	87	5	,	,	PUNCT
biomedich-739	87	6	fasting	fast	VERB
biomedich-739	87	7	blood	blood	NOUN
biomedich-739	87	8	glucose	glucose	NOUN
biomedich-739	87	9	levels	level	NOUN
biomedich-739	87	10	were	be	AUX
biomedich-739	87	11	assessed	assess	VERB
biomedich-739	87	12	,	,	PUNCT
biomedich-739	87	13	revealing	reveal	VERB
biomedich-739	87	14	an	an	DET
biomedich-739	87	15	elevation	elevation	NOUN
biomedich-739	87	16	relative	relative	ADJ
biomedich-739	87	17	to	to	ADP
biomedich-739	87	18	the	the	DET
biomedich-739	87	19	baseline	baseline	NOUN
biomedich-739	87	20	;	;	PUNCT
biomedich-739	87	21	this	this	PRON
biomedich-739	87	22	indicates	indicate	VERB
biomedich-739	87	23	successful	successful	ADJ
biomedich-739	87	24	induction	induction	NOUN
biomedich-739	87	25	of	of	ADP
biomedich-739	87	26	hyperglycemia	hyperglycemia	NOUN
biomedich-739	87	27	in	in	ADP
biomedich-739	87	28	t2d	t2d	NUM
biomedich-739	87	29	.	.	PUNCT
biomedich-739	88	1	the	the	DET
biomedich-739	88	2	pathogenesis	pathogenesis	NOUN
biomedich-739	88	3	of	of	ADP
biomedich-739	88	4	t2d	t2d	NOUN
biomedich-739	88	5	involves	involve	VERB
biomedich-739	88	6	several	several	ADJ
biomedich-739	88	7	factors	factor	NOUN
biomedich-739	88	8	,	,	PUNCT
biomedich-739	88	9	including	include	VERB
biomedich-739	88	10	impaired	impaired	ADJ
biomedich-739	88	11	insulin	insulin	NOUN
biomedich-739	88	12	secretion	secretion	NOUN
biomedich-739	88	13	by	by	ADP
biomedich-739	88	14	pancreatic	pancreatic	ADJ
biomedich-739	88	15	ß	ß	NOUN
biomedich-739	88	16	cells	cell	NOUN
biomedich-739	88	17	and	and	CCONJ
biomedich-739	88	18	insulin	insulin	NOUN
biomedich-739	88	19	resistance	resistance	NOUN
biomedich-739	88	20	in	in	ADP
biomedich-739	88	21	peripheral	peripheral	ADJ
biomedich-739	88	22	tissues	tissue	NOUN
biomedich-739	88	23	.	.	PUNCT
biomedich-739	89	1	this	this	DET
biomedich-739	89	2	condition	condition	NOUN
biomedich-739	89	3	leads	lead	VERB
biomedich-739	89	4	to	to	ADP
biomedich-739	89	5	a	a	DET
biomedich-739	89	6	heterogeneous	heterogeneous	ADJ
biomedich-739	89	7	condition	condition	NOUN
biomedich-739	89	8	characterized	characterize	VERB
biomedich-739	89	9	by	by	ADP
biomedich-739	89	10	β	β	X
biomedich-739	89	11	cell	cell	NOUN
biomedich-739	89	12	failure	failure	NOUN
biomedich-739	89	13	,	,	PUNCT
biomedich-739	89	14	ultimately	ultimately	ADV
biomedich-739	89	15	resulting	result	VERB
biomedich-739	89	16	in	in	ADP
biomedich-739	89	17	t2d	t2d	PROPN
biomedich-739	89	18	.	.	PUNCT
biomedich-739	90	1	streptozotocin	streptozotocin	PROPN
biomedich-739	90	2	has	have	VERB
biomedich-739	90	3	toxic	toxic	ADJ
biomedich-739	90	4	properties	property	NOUN
biomedich-739	90	5	because	because	SCONJ
biomedich-739	90	6	of	of	ADP
biomedich-739	90	7	its	its	PRON
biomedich-739	90	8	potential	potential	NOUN
biomedich-739	90	9	to	to	PART
biomedich-739	90	10	damage	damage	NOUN
biomedich-739	90	11	cells	cell	NOUN
biomedich-739	90	12	β	β	VERB
biomedich-739	90	13	the	the	DET
biomedich-739	90	14	pancreas	pancrea	NOUN
biomedich-739	90	15	and	and	CCONJ
biomedich-739	90	16	impact	impact	VERB
biomedich-739	90	17	the	the	DET
biomedich-739	90	18	expression	expression	NOUN
biomedich-739	90	19	of	of	ADP
biomedich-739	90	20	the	the	DET
biomedich-739	90	21	glut-2	glut-2	PROPN
biomedich-739	90	22	protein	protein	NOUN
biomedich-739	90	23	which	which	PRON
biomedich-739	90	24	causes	cause	VERB
biomedich-739	90	25	increased	increase	VERB
biomedich-739	90	26	blood	blood	NOUN
biomedich-739	90	27	glucose	glucose	NOUN
biomedich-739	90	28	levels	level	NOUN
biomedich-739	90	29	in	in	ADP
biomedich-739	90	30	test	test	NOUN
biomedich-739	90	31	animals	animal	NOUN
biomedich-739	90	32	.	.	PUNCT
biomedich-739	91	1	stz	stz	NOUN
biomedich-739	91	2	works	work	VERB
biomedich-739	91	3	by	by	ADP
biomedich-739	91	4	forming	form	VERB
biomedich-739	91	5	free	free	ADJ
biomedich-739	91	6	radicals	radical	NOUN
biomedich-739	91	7	that	that	PRON
biomedich-739	91	8	damage	damage	VERB
biomedich-739	91	9	pancreatic	pancreatic	ADJ
biomedich-739	91	10	beta	beta	NOUN
biomedich-739	91	11	cells	cell	NOUN
biomedich-739	91	12	resulting	result	VERB
biomedich-739	91	13	in	in	ADP
biomedich-739	91	14	hyperglycemia	hyperglycemia	NOUN
biomedich-739	91	15	and	and	CCONJ
biomedich-739	91	16	hypoinsulinemia	hypoinsulinemia	NOUN
biomedich-739	91	17	(	(	PUNCT
biomedich-739	91	18	munjiati	munjiati	PROPN
biomedich-739	91	19	et	et	PROPN
biomedich-739	91	20	al	al	PROPN
biomedich-739	91	21	.	.	PROPN
biomedich-739	91	22	,	,	PUNCT
biomedich-739	91	23	2021	2021	NUM
biomedich-739	91	24	)	)	PUNCT
biomedich-739	91	25	.	.	PUNCT
biomedich-739	92	1	nicotinamide	nicotinamide	NOUN
biomedich-739	92	2	(	(	PUNCT
biomedich-739	92	3	nta	nta	PROPN
biomedich-739	92	4	)	)	PUNCT
biomedich-739	92	5	effectively	effectively	ADV
biomedich-739	92	6	protects	protect	VERB
biomedich-739	92	7	β	β	NOUN
biomedich-739	92	8	cells	cell	NOUN
biomedich-739	92	9	against	against	ADP
biomedich-739	92	10	stz	stz	NOUN
biomedich-739	92	11	cytotoxicity	cytotoxicity	NOUN
biomedich-739	92	12	,	,	PUNCT
biomedich-739	92	13	nta	nta	PROPN
biomedich-739	92	14	attenuates	attenuate	NOUN
biomedich-739	92	15	diabetes	diabetes	NOUN
biomedich-739	92	16	complications	complication	NOUN
biomedich-739	92	17	caused	cause	VERB
biomedich-739	92	18	by	by	ADP
biomedich-739	92	19	streptozotocin	streptozotocin	NOUN
biomedich-739	92	20	and	and	CCONJ
biomedich-739	92	21	increases	increase	VERB
biomedich-739	92	22	360	360	NUM
biomedich-739	92	23	biology	biology	NOUN
biomedich-739	92	24	,	,	PUNCT
biomedich-739	92	25	medicine	medicine	NOUN
biomedich-739	92	26	,	,	PUNCT
biomedich-739	92	27	&	&	CCONJ
biomedich-739	92	28	natural	natural	ADJ
biomedich-739	92	29	product	product	NOUN
biomedich-739	92	30	chemistry	chemistry	NOUN
biomedich-739	92	31	14	14	NUM
biomedich-739	92	32	(	(	PUNCT
biomedich-739	92	33	1	1	NUM
biomedich-739	92	34	)	)	PUNCT
biomedich-739	92	35	,	,	PUNCT
biomedich-739	92	36	2025	2025	NUM
biomedich-739	92	37	:	:	PUNCT
biomedich-739	92	38	357	357	NUM
biomedich-739	92	39	-	-	SYM
biomedich-739	92	40	361	361	NUM
biomedich-739	92	41	survival	survival	NOUN
biomedich-739	92	42	rates	rate	NOUN
biomedich-739	92	43	in	in	ADP
biomedich-739	92	44	mice	mouse	NOUN
biomedich-739	92	45	.	.	PUNCT
biomedich-739	93	1	protection	protection	NOUN
biomedich-739	93	2	from	from	ADP
biomedich-739	93	3	try	try	NOUN
biomedich-739	93	4	animals	animal	NOUN
biomedich-739	93	5	depends	depend	VERB
biomedich-739	93	6	on	on	ADP
biomedich-739	93	7	decreasing	decrease	VERB
biomedich-739	93	8	the	the	DET
biomedich-739	93	9	damage	damage	NOUN
biomedich-739	93	10	and	and	CCONJ
biomedich-739	93	11	methylation	methylation	NOUN
biomedich-739	93	12	of	of	ADP
biomedich-739	93	13	deoxyribonucleic	deoxyribonucleic	ADJ
biomedich-739	93	14	acid	acid	NOUN
biomedich-739	93	15	(	(	PUNCT
biomedich-739	93	16	dna	dna	PROPN
biomedich-739	93	17	)	)	PUNCT
biomedich-739	93	18	in	in	ADP
biomedich-739	93	19	the	the	DET
biomedich-739	93	20	pancreatic	pancreatic	ADJ
biomedich-739	93	21	islets	islet	NOUN
biomedich-739	93	22	,	,	PUNCT
biomedich-739	93	23	increased	increase	VERB
biomedich-739	93	24	insulin	insulin	NOUN
biomedich-739	93	25	secretion	secretion	NOUN
biomedich-739	93	26	,	,	PUNCT
biomedich-739	93	27	nerve	nerve	NOUN
biomedich-739	93	28	protection	protection	NOUN
biomedich-739	93	29	function	function	NOUN
biomedich-739	93	30	and	and	CCONJ
biomedich-739	93	31	.	.	PUNCT
biomedich-739	94	1	nicotinamide	nicotinamide	NOUN
biomedich-739	94	2	(	(	PUNCT
biomedich-739	94	3	pyridine-3	pyridine-3	NOUN
biomedich-739	94	4	-	-	PUNCT
biomedich-739	94	5	carbosamide	carbosamide	NOUN
biomedich-739	94	6	)	)	PUNCT
biomedich-739	94	7	is	be	AUX
biomedich-739	94	8	an	an	DET
biomedich-739	94	9	amide	amide	NOUN
biomedich-739	94	10	form	form	NOUN
biomedich-739	94	11	of	of	ADP
biomedich-739	94	12	vitamin	vitamin	NOUN
biomedich-739	94	13	b3	b3	NOUN
biomedich-739	94	14	or	or	CCONJ
biomedich-739	94	15	niacin	niacin	NOUN
biomedich-739	94	16	.	.	PUNCT
biomedich-739	95	1	nicotinamide	nicotinamide	NOUN
biomedich-739	95	2	is	be	AUX
biomedich-739	95	3	a	a	DET
biomedich-739	95	4	percussor	percussor	NOUN
biomedich-739	95	5	of	of	ADP
biomedich-739	95	6	nicotinamide	nicotinamide	NOUN
biomedich-739	95	7	adenine	adenine	ADJ
biomedich-739	95	8	dinucleotide	dinucleotide	NOUN
biomedich-739	95	9	(	(	PUNCT
biomedich-739	95	10	nad	nad	NOUN
biomedich-739	95	11	)	)	PUNCT
biomedich-739	95	12	and	and	CCONJ
biomedich-739	95	13	nicotinamide	nicotinamide	NOUN
biomedich-739	95	14	adenine	adenine	ADJ
biomedich-739	95	15	dinucleotide	dinucleotide	NOUN
biomedich-739	95	16	phosphate	phosphate	NOUN
biomedich-739	95	17	(	(	PUNCT
biomedich-739	95	18	nadp	nadp	PROPN
biomedich-739	95	19	)	)	PUNCT
biomedich-739	95	20	which	which	PRON
biomedich-739	95	21	can	can	AUX
biomedich-739	95	22	protect	protect	VERB
biomedich-739	95	23	pancreatic	pancreatic	ADJ
biomedich-739	95	24	β	β	NOUN
biomedich-739	95	25	cells	cell	NOUN
biomedich-739	95	26	from	from	ADP
biomedich-739	95	27	various	various	ADJ
biomedich-739	95	28	toxic	toxic	ADJ
biomedich-739	95	29	substances	substance	NOUN
biomedich-739	95	30	.	.	PUNCT
biomedich-739	96	1	on	on	ADP
biomedich-739	96	2	the	the	DET
biomedich-739	96	3	other	other	ADJ
biomedich-739	96	4	hand	hand	NOUN
biomedich-739	96	5	,	,	PUNCT
biomedich-739	96	6	nicotinamide	nicotinamide	NOUN
biomedich-739	96	7	protects	protect	VERB
biomedich-739	96	8	cells	cell	NOUN
biomedich-739	96	9	β	β	VERB
biomedich-739	96	10	the	the	DET
biomedich-739	96	11	pancreas	pancreas	NOUN
biomedich-739	96	12	from	from	ADP
biomedich-739	96	13	dna	dna	PROPN
biomedich-739	96	14	damage	damage	NOUN
biomedich-739	96	15	,	,	PUNCT
biomedich-739	96	16	therefore	therefore	ADV
biomedich-739	96	17	nicotinamide	nicotinamide	NOUN
biomedich-739	96	18	can	can	AUX
biomedich-739	96	19	cope	cope	VERB
biomedich-739	96	20	with	with	ADP
biomedich-739	96	21	stzinduced	stzinduce	VERB
biomedich-739	96	22	diabetes	diabetes	NOUN
biomedich-739	96	23	,	,	PUNCT
biomedich-739	96	24	increased	increased	ADJ
biomedich-739	96	25	hyperglycemia	hyperglycemia	NOUN
biomedich-739	96	26	and	and	CCONJ
biomedich-739	96	27	weight	weight	NOUN
biomedich-739	96	28	loss	loss	NOUN
biomedich-739	96	29	(	(	PUNCT
biomedich-739	96	30	cruz	cruz	PROPN
biomedich-739	96	31	et	et	PROPN
biomedich-739	96	32	al	al	PROPN
biomedich-739	96	33	.	.	PROPN
biomedich-739	96	34	,	,	PUNCT
biomedich-739	96	35	2019	2019	NUM
biomedich-739	96	36	)	)	PUNCT
biomedich-739	96	37	.	.	PUNCT
biomedich-739	97	1	the	the	DET
biomedich-739	97	2	differential	differential	ADJ
biomedich-739	97	3	test	test	NOUN
biomedich-739	97	4	findings	finding	NOUN
biomedich-739	97	5	across	across	ADP
biomedich-739	97	6	groups	group	NOUN
biomedich-739	97	7	indicated	indicate	VERB
biomedich-739	97	8	no	no	DET
biomedich-739	97	9	significant	significant	ADJ
biomedich-739	97	10	differences	difference	NOUN
biomedich-739	97	11	,	,	PUNCT
biomedich-739	97	12	despite	despite	SCONJ
biomedich-739	97	13	a	a	DET
biomedich-739	97	14	reduction	reduction	NOUN
biomedich-739	97	15	in	in	ADP
biomedich-739	97	16	blood	blood	NOUN
biomedich-739	97	17	glucose	glucose	NOUN
biomedich-739	97	18	levels	level	NOUN
biomedich-739	97	19	following	follow	VERB
biomedich-739	97	20	the	the	DET
biomedich-739	97	21	administration	administration	NOUN
biomedich-739	97	22	of	of	ADP
biomedich-739	97	23	orthosiphon	orthosiphon	ADJ
biomedich-739	97	24	aristatus	aristatus	NOUN
biomedich-739	97	25	leaf	leaf	NOUN
biomedich-739	97	26	extract	extract	NOUN
biomedich-739	97	27	.	.	PUNCT
biomedich-739	98	1	the	the	DET
biomedich-739	98	2	extract	extract	NOUN
biomedich-739	98	3	's	's	PART
biomedich-739	98	4	mechanism	mechanism	NOUN
biomedich-739	98	5	of	of	ADP
biomedich-739	98	6	action	action	NOUN
biomedich-739	98	7	is	be	AUX
biomedich-739	98	8	intricate	intricate	ADJ
biomedich-739	98	9	and	and	CCONJ
biomedich-739	98	10	not	not	PART
biomedich-739	98	11	yet	yet	ADV
biomedich-739	98	12	completely	completely	ADV
biomedich-739	98	13	comprehended	comprehend	VERB
biomedich-739	98	14	.	.	PUNCT
biomedich-739	99	1	stz	stz	NOUN
biomedich-739	99	2	possesses	possess	VERB
biomedich-739	99	3	the	the	DET
biomedich-739	99	4	capability	capability	NOUN
biomedich-739	99	5	to	to	PART
biomedich-739	99	6	limit	limit	VERB
biomedich-739	99	7	dna	dna	PROPN
biomedich-739	99	8	synthesis	synthesis	NOUN
biomedich-739	99	9	,	,	PUNCT
biomedich-739	99	10	induce	induce	VERB
biomedich-739	99	11	cellular	cellular	ADJ
biomedich-739	99	12	apoptosis	apoptosis	NOUN
biomedich-739	99	13	,	,	PUNCT
biomedich-739	99	14	and	and	CCONJ
biomedich-739	99	15	hinder	hinder	VERB
biomedich-739	99	16	cellular	cellular	ADJ
biomedich-739	99	17	regeneration	regeneration	NOUN
biomedich-739	99	18	(	(	PUNCT
biomedich-739	99	19	harijanto	harijanto	NOUN
biomedich-739	99	20	&	&	CCONJ
biomedich-739	99	21	dewajanti	dewajanti	PROPN
biomedich-739	99	22	,	,	PUNCT
biomedich-739	99	23	2017	2017	NUM
biomedich-739	99	24	)	)	PUNCT
biomedich-739	99	25	.	.	PUNCT
biomedich-739	100	1	the	the	DET
biomedich-739	100	2	use	use	NOUN
biomedich-739	100	3	of	of	ADP
biomedich-739	100	4	nicotinamide	nicotinamide	NOUN
biomedich-739	100	5	(	(	PUNCT
biomedich-739	100	6	nta	nta	PROPN
biomedich-739	100	7	)	)	PUNCT
biomedich-739	100	8	is	be	AUX
biomedich-739	100	9	aimed	aim	VERB
biomedich-739	100	10	at	at	ADP
biomedich-739	100	11	protecting	protect	VERB
biomedich-739	100	12	against	against	ADP
biomedich-739	100	13	pancreatic	pancreatic	ADJ
biomedich-739	100	14	damage	damage	NOUN
biomedich-739	100	15	,	,	PUNCT
biomedich-739	100	16	preventing	prevent	VERB
biomedich-739	100	17	it	it	PRON
biomedich-739	100	18	from	from	ADP
biomedich-739	100	19	becoming	become	VERB
biomedich-739	100	20	acute	acute	ADJ
biomedich-739	100	21	.	.	PUNCT
biomedich-739	101	1	nicotinamide	nicotinamide	NOUN
biomedich-739	101	2	(	(	PUNCT
biomedich-739	101	3	nta	nta	PROPN
biomedich-739	101	4	)	)	PUNCT
biomedich-739	101	5	effectively	effectively	ADV
biomedich-739	101	6	protects	protect	VERB
biomedich-739	101	7	β	β	NOUN
biomedich-739	101	8	cells	cell	NOUN
biomedich-739	101	9	against	against	ADP
biomedich-739	101	10	stz	stz	NOUN
biomedich-739	101	11	cytotoxicity	cytotoxicity	NOUN
biomedich-739	101	12	,	,	PUNCT
biomedich-739	101	13	nta	nta	PROPN
biomedich-739	101	14	attenuates	attenuate	NOUN
biomedich-739	101	15	diabetes	diabetes	NOUN
biomedich-739	101	16	complications	complication	NOUN
biomedich-739	101	17	caused	cause	VERB
biomedich-739	101	18	by	by	ADP
biomedich-739	101	19	streptozotocin	streptozotocin	NOUN
biomedich-739	101	20	and	and	CCONJ
biomedich-739	101	21	increases	increase	VERB
biomedich-739	101	22	survival	survival	NOUN
biomedich-739	101	23	rates	rate	NOUN
biomedich-739	101	24	in	in	ADP
biomedich-739	101	25	mice	mouse	NOUN
biomedich-739	101	26	.	.	PUNCT
biomedich-739	102	1	protection	protection	NOUN
biomedich-739	102	2	from	from	ADP
biomedich-739	102	3	try	try	NOUN
biomedich-739	102	4	animals	animal	NOUN
biomedich-739	102	5	depends	depend	VERB
biomedich-739	102	6	on	on	ADP
biomedich-739	102	7	decreasing	decrease	VERB
biomedich-739	102	8	the	the	DET
biomedich-739	102	9	damage	damage	NOUN
biomedich-739	102	10	and	and	CCONJ
biomedich-739	102	11	methylation	methylation	NOUN
biomedich-739	102	12	of	of	ADP
biomedich-739	102	13	deoxyribonucleic	deoxyribonucleic	ADJ
biomedich-739	102	14	acid	acid	NOUN
biomedich-739	102	15	(	(	PUNCT
biomedich-739	102	16	dna	dna	PROPN
biomedich-739	102	17	)	)	PUNCT
biomedich-739	102	18	in	in	ADP
biomedich-739	102	19	the	the	DET
biomedich-739	102	20	pancreatic	pancreatic	ADJ
biomedich-739	102	21	islets	islet	NOUN
biomedich-739	102	22	,	,	PUNCT
biomedich-739	102	23	increased	increase	VERB
biomedich-739	102	24	insulin	insulin	NOUN
biomedich-739	102	25	secretion	secretion	NOUN
biomedich-739	102	26	,	,	PUNCT
biomedich-739	102	27	nerve	nerve	NOUN
biomedich-739	102	28	protection	protection	NOUN
biomedich-739	102	29	function	function	NOUN
biomedich-739	102	30	and	and	CCONJ
biomedich-739	102	31	.	.	PUNCT
biomedich-739	103	1	nicotinamide	nicotinamide	NOUN
biomedich-739	103	2	(	(	PUNCT
biomedich-739	103	3	pyridine-3	pyridine-3	NOUN
biomedich-739	103	4	-	-	PUNCT
biomedich-739	103	5	carbosamide	carbosamide	NOUN
biomedich-739	103	6	)	)	PUNCT
biomedich-739	103	7	is	be	AUX
biomedich-739	103	8	an	an	DET
biomedich-739	103	9	amide	amide	NOUN
biomedich-739	103	10	form	form	NOUN
biomedich-739	103	11	of	of	ADP
biomedich-739	103	12	vitamin	vitamin	NOUN
biomedich-739	103	13	b3	b3	NOUN
biomedich-739	103	14	or	or	CCONJ
biomedich-739	103	15	niacin	niacin	NOUN
biomedich-739	103	16	.	.	PUNCT
biomedich-739	104	1	nicotinamide	nicotinamide	NOUN
biomedich-739	104	2	is	be	AUX
biomedich-739	104	3	a	a	DET
biomedich-739	104	4	percussor	percussor	NOUN
biomedich-739	104	5	of	of	ADP
biomedich-739	104	6	nicotinamide	nicotinamide	NOUN
biomedich-739	104	7	adenine	adenine	ADJ
biomedich-739	104	8	dinucleotide	dinucleotide	NOUN
biomedich-739	104	9	(	(	PUNCT
biomedich-739	104	10	nad	nad	NOUN
biomedich-739	104	11	)	)	PUNCT
biomedich-739	104	12	and	and	CCONJ
biomedich-739	104	13	nicotinamide	nicotinamide	NOUN
biomedich-739	104	14	adenine	adenine	ADJ
biomedich-739	104	15	dinucleotide	dinucleotide	NOUN
biomedich-739	104	16	phosphate	phosphate	NOUN
biomedich-739	104	17	(	(	PUNCT
biomedich-739	104	18	nadp	nadp	PROPN
biomedich-739	104	19	)	)	PUNCT
biomedich-739	104	20	which	which	PRON
biomedich-739	104	21	can	can	AUX
biomedich-739	104	22	protect	protect	VERB
biomedich-739	104	23	pancreatic	pancreatic	ADJ
biomedich-739	104	24	β	β	NOUN
biomedich-739	104	25	cells	cell	NOUN
biomedich-739	104	26	from	from	ADP
biomedich-739	104	27	various	various	ADJ
biomedich-739	104	28	toxic	toxic	ADJ
biomedich-739	104	29	substances	substance	NOUN
biomedich-739	104	30	(	(	PUNCT
biomedich-739	104	31	cruz	cruz	NOUN
biomedich-739	104	32	et	et	PROPN
biomedich-739	104	33	al	al	PROPN
biomedich-739	104	34	.	.	PROPN
biomedich-739	104	35	,	,	PUNCT
biomedich-739	104	36	2019	2019	NUM
biomedich-739	104	37	)	)	PUNCT
biomedich-739	104	38	.	.	PUNCT
biomedich-739	105	1	this	this	DET
biomedich-739	105	2	study	study	NOUN
biomedich-739	105	3	observed	observe	VERB
biomedich-739	105	4	the	the	DET
biomedich-739	105	5	expression	expression	NOUN
biomedich-739	105	6	of	of	ADP
biomedich-739	105	7	col1a1	col1a1	NOUN
biomedich-739	105	8	quantitatively	quantitatively	ADV
biomedich-739	105	9	using	use	VERB
biomedich-739	105	10	the	the	DET
biomedich-739	105	11	analysis	analysis	NOUN
biomedich-739	105	12	of	of	ADP
biomedich-739	105	13	the	the	DET
biomedich-739	105	14	cycle	cycle	NOUN
biomedich-739	105	15	of	of	ADP
biomedich-739	105	16	tresh	tresh	NOUN
biomedich-739	105	17	hold	hold	NOUN
biomedich-739	105	18	(	(	PUNCT
biomedich-739	105	19	ct	ct	NOUN
biomedich-739	105	20	)	)	PUNCT
biomedich-739	105	21	value	value	NOUN
biomedich-739	105	22	of	of	ADP
biomedich-739	105	23	the	the	DET
biomedich-739	105	24	col1a1	col1a1	NOUN
biomedich-739	105	25	gene	gene	NOUN
biomedich-739	105	26	mrna	mrna	PROPN
biomedich-739	105	27	to	to	ADP
biomedich-739	105	28	the	the	DET
biomedich-739	105	29	ct	ct	NOUN
biomedich-739	105	30	of	of	ADP
biomedich-739	105	31	the	the	DET
biomedich-739	105	32	internal	internal	ADJ
biomedich-739	105	33	gene	gene	NOUN
biomedich-739	105	34	β	β	NOUN
biomedich-739	105	35	-	-	NOUN
biomedich-739	105	36	actin	actin	NOUN
biomedich-739	105	37	.	.	PUNCT
biomedich-739	106	1	the	the	DET
biomedich-739	106	2	results	result	NOUN
biomedich-739	106	3	of	of	ADP
biomedich-739	106	4	the	the	DET
biomedich-739	106	5	col1a1	col1a1	NOUN
biomedich-739	106	6	gene	gene	NOUN
biomedich-739	106	7	expression	expression	NOUN
biomedich-739	106	8	difference	difference	NOUN
biomedich-739	106	9	test	test	NOUN
biomedich-739	106	10	with	with	ADP
biomedich-739	106	11	the	the	DET
biomedich-739	106	12	kruskal	kruskal	PROPN
biomedich-739	106	13	wallis	wallis	PROPN
biomedich-739	106	14	test	test	NOUN
biomedich-739	106	15	showed	show	VERB
biomedich-739	106	16	no	no	DET
biomedich-739	106	17	significant	significant	ADJ
biomedich-739	106	18	difference	difference	NOUN
biomedich-739	106	19	in	in	ADP
biomedich-739	106	20	gene	gene	NOUN
biomedich-739	106	21	expression	expression	NOUN
biomedich-739	106	22	levels	level	NOUN
biomedich-739	106	23	between	between	ADP
biomedich-739	106	24	groups	group	NOUN
biomedich-739	106	25	,	,	PUNCT
biomedich-739	106	26	the	the	DET
biomedich-739	106	27	same	same	ADJ
biomedich-739	106	28	results	result	NOUN
biomedich-739	106	29	were	be	AUX
biomedich-739	106	30	shown	show	VERB
biomedich-739	106	31	by	by	ADP
biomedich-739	106	32	the	the	DET
biomedich-739	106	33	correlation	correlation	NOUN
biomedich-739	106	34	test	test	NOUN
biomedich-739	106	35	between	between	ADP
biomedich-739	106	36	blood	blood	NOUN
biomedich-739	106	37	sugar	sugar	NOUN
biomedich-739	106	38	levels	level	NOUN
biomedich-739	106	39	and	and	CCONJ
biomedich-739	106	40	gene	gene	NOUN
biomedich-739	106	41	expression	expression	NOUN
biomedich-739	106	42	with	with	ADP
biomedich-739	106	43	the	the	DET
biomedich-739	106	44	spearman	spearman	NOUN
biomedich-739	106	45	's	's	PART
biomedich-739	106	46	rho	rho	ADJ
biomedich-739	106	47	test	test	NOUN
biomedich-739	106	48	with	with	ADP
biomedich-739	106	49	a	a	DET
biomedich-739	106	50	value	value	NOUN
biomedich-739	106	51	of	of	ADP
biomedich-739	106	52	p>0.05	p>0.05	PROPN
biomedich-739	106	53	(	(	PUNCT
biomedich-739	106	54	table	table	NOUN
biomedich-739	106	55	2	2	NUM
biomedich-739	106	56	)	)	PUNCT
biomedich-739	106	57	.	.	PUNCT
biomedich-739	107	1	this	this	PRON
biomedich-739	107	2	is	be	AUX
biomedich-739	107	3	possible	possible	ADJ
biomedich-739	107	4	because	because	SCONJ
biomedich-739	107	5	the	the	DET
biomedich-739	107	6	expression	expression	NOUN
biomedich-739	107	7	process	process	NOUN
biomedich-739	107	8	of	of	ADP
biomedich-739	107	9	the	the	DET
biomedich-739	107	10	col1a1	col1a1	NOUN
biomedich-739	107	11	gene	gene	NOUN
biomedich-739	107	12	(	(	PUNCT
biomedich-739	107	13	col1a1	col1a1	NOUN
biomedich-739	107	14	protein	protein	NOUN
biomedich-739	107	15	synthesis	synthesis	NOUN
biomedich-739	107	16	)	)	PUNCT
biomedich-739	107	17	is	be	AUX
biomedich-739	107	18	influenced	influence	VERB
biomedich-739	107	19	by	by	ADP
biomedich-739	107	20	various	various	ADJ
biomedich-739	107	21	factors	factor	NOUN
biomedich-739	107	22	both	both	CCONJ
biomedich-739	107	23	intracellular	intracellular	ADJ
biomedich-739	107	24	and	and	CCONJ
biomedich-739	107	25	extracellular	extracellular	ADJ
biomedich-739	107	26	,	,	PUNCT
biomedich-739	107	27	both	both	CCONJ
biomedich-739	107	28	at	at	ADP
biomedich-739	107	29	the	the	DET
biomedich-739	107	30	transcription	transcription	NOUN
biomedich-739	107	31	,	,	PUNCT
biomedich-739	107	32	post	post	NOUN
biomedich-739	107	33	-	-	NOUN
biomedich-739	107	34	transcription	transcription	NOUN
biomedich-739	107	35	,	,	PUNCT
biomedich-739	107	36	and	and	CCONJ
biomedich-739	107	37	post	post	ADJ
biomedich-739	107	38	-	-	ADJ
biomedich-739	107	39	translational	translational	ADJ
biomedich-739	107	40	levels	level	NOUN
biomedich-739	107	41	.	.	PUNCT
biomedich-739	108	1	the	the	DET
biomedich-739	108	2	col1a1	col1a1	NOUN
biomedich-739	108	3	protein	protein	NOUN
biomedich-739	108	4	is	be	AUX
biomedich-739	108	5	a	a	DET
biomedich-739	108	6	protein	protein	NOUN
biomedich-739	108	7	that	that	PRON
biomedich-739	108	8	plays	play	VERB
biomedich-739	108	9	a	a	DET
biomedich-739	108	10	role	role	NOUN
biomedich-739	108	11	in	in	ADP
biomedich-739	108	12	the	the	DET
biomedich-739	108	13	interaction	interaction	NOUN
biomedich-739	108	14	of	of	ADP
biomedich-739	108	15	the	the	DET
biomedich-739	108	16	extracellular	extracellular	ADJ
biomedich-739	108	17	matrix	matrix	NOUN
biomedich-739	108	18	(	(	PUNCT
biomedich-739	108	19	ecm	ecm	PROPN
biomedich-739	108	20	)	)	PUNCT
biomedich-739	108	21	,	,	PUNCT
biomedich-739	108	22	the	the	DET
biomedich-739	108	23	link	link	NOUN
biomedich-739	108	24	between	between	ADP
biomedich-739	108	25	the	the	DET
biomedich-739	108	26	col1a1	col1a1	NOUN
biomedich-739	108	27	protein	protein	NOUN
biomedich-739	108	28	and	and	CCONJ
biomedich-739	108	29	diabetes	diabetes	NOUN
biomedich-739	108	30	mellitus	mellitus	NOUN
biomedich-739	108	31	occurs	occur	VERB
biomedich-739	108	32	through	through	ADP
biomedich-739	108	33	the	the	DET
biomedich-739	108	34	ecmreceptor	ecmreceptor	NOUN
biomedich-739	108	35	interaction	interaction	NOUN
biomedich-739	108	36	pathway	pathway	NOUN
biomedich-739	108	37	(	(	PUNCT
biomedich-739	108	38	lin	lin	PROPN
biomedich-739	108	39	et	et	PROPN
biomedich-739	108	40	al	al	PROPN
biomedich-739	108	41	.	.	PROPN
biomedich-739	108	42	,	,	PUNCT
biomedich-739	108	43	2021	2021	NUM
biomedich-739	108	44	)	)	PUNCT
biomedich-739	108	45	.	.	PUNCT
biomedich-739	109	1	the	the	DET
biomedich-739	109	2	results	result	NOUN
biomedich-739	109	3	of	of	ADP
biomedich-739	109	4	meaningless	meaningless	ADJ
biomedich-739	109	5	expression	expression	NOUN
biomedich-739	109	6	of	of	ADP
biomedich-739	109	7	col1a1	col1a1	NOUN
biomedich-739	109	8	genes	gene	NOUN
biomedich-739	109	9	between	between	ADP
biomedich-739	109	10	groups	group	NOUN
biomedich-739	109	11	can	can	AUX
biomedich-739	109	12	be	be	AUX
biomedich-739	109	13	influenced	influence	VERB
biomedich-739	109	14	by	by	ADP
biomedich-739	109	15	several	several	ADJ
biomedich-739	109	16	aspects	aspect	NOUN
biomedich-739	109	17	:	:	PUNCT
biomedich-739	109	18	(	(	PUNCT
biomedich-739	109	19	1	1	X
biomedich-739	109	20	)	)	PUNCT
biomedich-739	109	21	the	the	DET
biomedich-739	109	22	synthesis	synthesis	NOUN
biomedich-739	109	23	and	and	CCONJ
biomedich-739	109	24	processing	processing	NOUN
biomedich-739	109	25	of	of	ADP
biomedich-739	109	26	cola1	cola1	PROPN
biomedich-739	109	27	is	be	AUX
biomedich-739	109	28	a	a	DET
biomedich-739	109	29	complex	complex	ADJ
biomedich-739	109	30	process	process	NOUN
biomedich-739	109	31	involving	involve	VERB
biomedich-739	109	32	intracellular	intracellular	ADJ
biomedich-739	109	33	modifications	modification	NOUN
biomedich-739	109	34	such	such	ADJ
biomedich-739	109	35	as	as	ADP
biomedich-739	109	36	hydroxylation	hydroxylation	NOUN
biomedich-739	109	37	of	of	ADP
biomedich-739	109	38	proline	proline	NOUN
biomedich-739	109	39	,	,	PUNCT
biomedich-739	109	40	lysine	lysine	NOUN
biomedich-739	109	41	,	,	PUNCT
biomedich-739	109	42	and	and	CCONJ
biomedich-739	109	43	glycosylation	glycosylation	NOUN
biomedich-739	109	44	,	,	PUNCT
biomedich-739	109	45	which	which	PRON
biomedich-739	109	46	are	be	AUX
biomedich-739	109	47	important	important	ADJ
biomedich-739	109	48	for	for	ADP
biomedich-739	109	49	the	the	DET
biomedich-739	109	50	stability	stability	NOUN
biomedich-739	109	51	of	of	ADP
biomedich-739	109	52	collagen	collagen	NOUN
biomedich-739	109	53	structure	structure	NOUN
biomedich-739	109	54	.	.	PUNCT
biomedich-739	110	1	once	once	ADV
biomedich-739	110	2	secreted	secrete	VERB
biomedich-739	110	3	,	,	PUNCT
biomedich-739	110	4	procollagen	procollagen	NOUN
biomedich-739	110	5	undergoes	undergo	VERB
biomedich-739	110	6	proteolytic	proteolytic	ADJ
biomedich-739	110	7	breakdown	breakdown	NOUN
biomedich-739	110	8	and	and	CCONJ
biomedich-739	110	9	the	the	DET
biomedich-739	110	10	formation	formation	NOUN
biomedich-739	110	11	of	of	ADP
biomedich-739	110	12	cross	cross	NOUN
biomedich-739	110	13	-	-	NOUN
biomedich-739	110	14	links	link	NOUN
biomedich-739	110	15	in	in	ADP
biomedich-739	110	16	the	the	DET
biomedich-739	110	17	extracellular	extracellular	ADJ
biomedich-739	110	18	matrix	matrix	NOUN
biomedich-739	110	19	,	,	PUNCT
biomedich-739	110	20	which	which	PRON
biomedich-739	110	21	results	result	VERB
biomedich-739	110	22	in	in	ADP
biomedich-739	110	23	mature	mature	ADJ
biomedich-739	110	24	collagen	collagen	NOUN
biomedich-739	110	25	fibrils	fibril	NOUN
biomedich-739	110	26	.	.	PUNCT
biomedich-739	111	1	this	this	DET
biomedich-739	111	2	process	process	NOUN
biomedich-739	111	3	is	be	AUX
biomedich-739	111	4	controlled	control	VERB
biomedich-739	111	5	by	by	ADP
biomedich-739	111	6	various	various	ADJ
biomedich-739	111	7	regulatory	regulatory	ADJ
biomedich-739	111	8	mechanisms	mechanism	NOUN
biomedich-739	111	9	,	,	PUNCT
biomedich-739	111	10	including	include	VERB
biomedich-739	111	11	epigenetics	epigenetic	NOUN
biomedich-739	111	12	(	(	PUNCT
biomedich-739	111	13	dna	dna	NOUN
biomedich-739	111	14	methylation	methylation	NOUN
biomedich-739	111	15	,	,	PUNCT
biomedich-739	111	16	histone	histone	NOUN
biomedich-739	111	17	modification	modification	NOUN
biomedich-739	111	18	)	)	PUNCT
biomedich-739	111	19	,	,	PUNCT
biomedich-739	111	20	transcription	transcription	NOUN
biomedich-739	111	21	(	(	PUNCT
biomedich-739	111	22	activation	activation	NOUN
biomedich-739	111	23	by	by	ADP
biomedich-739	111	24	transcription	transcription	NOUN
biomedich-739	111	25	factors	factor	NOUN
biomedich-739	111	26	such	such	ADJ
biomedich-739	111	27	as	as	ADP
biomedich-739	111	28	sp1	sp1	NOUN
biomedich-739	111	29	,	,	PUNCT
biomedich-739	111	30	ap-1	ap-1	ADV
biomedich-739	111	31	,	,	PUNCT
biomedich-739	111	32	and	and	CCONJ
biomedich-739	111	33	runx2	runx2	NOUN
biomedich-739	111	34	)	)	PUNCT
biomedich-739	111	35	,	,	PUNCT
biomedich-739	111	36	post	post	ADJ
biomedich-739	111	37	-	-	NOUN
biomedich-739	111	38	transcription	transcription	NOUN
biomedich-739	111	39	(	(	PUNCT
biomedich-739	111	40	regulation	regulation	NOUN
biomedich-739	111	41	by	by	ADP
biomedich-739	111	42	mirnas	mirna	NOUN
biomedich-739	111	43	such	such	ADJ
biomedich-739	111	44	as	as	ADP
biomedich-739	111	45	mir29	mir29	NOUN
biomedich-739	111	46	)	)	PUNCT
biomedich-739	111	47	,	,	PUNCT
biomedich-739	111	48	as	as	ADV
biomedich-739	111	49	well	well	ADV
biomedich-739	111	50	as	as	ADP
biomedich-739	111	51	post	post	ADJ
biomedich-739	111	52	-	-	ADJ
biomedich-739	111	53	translational	translational	ADJ
biomedich-739	111	54	modification	modification	NOUN
biomedich-739	111	55	(	(	PUNCT
biomedich-739	111	56	hydroxylation	hydroxylation	NOUN
biomedich-739	111	57	,	,	PUNCT
biomedich-739	111	58	glycosylation	glycosylation	NOUN
biomedich-739	111	59	,	,	PUNCT
biomedich-739	111	60	and	and	CCONJ
biomedich-739	111	61	proteolytic	proteolytic	ADJ
biomedich-739	111	62	breakdown	breakdown	NOUN
biomedich-739	111	63	)	)	PUNCT
biomedich-739	111	64	,	,	PUNCT
biomedich-739	111	65	which	which	PRON
biomedich-739	111	66	overall	overall	ADJ
biomedich-739	111	67	determine	determine	VERB
biomedich-739	111	68	the	the	DET
biomedich-739	111	69	final	final	ADJ
biomedich-739	111	70	structure	structure	NOUN
biomedich-739	111	71	and	and	CCONJ
biomedich-739	111	72	function	function	NOUN
biomedich-739	111	73	of	of	ADP
biomedich-739	111	74	collagen	collagen	NOUN
biomedich-739	111	75	in	in	ADP
biomedich-739	111	76	tissues	tissue	NOUN
biomedich-739	111	77	,	,	PUNCT
biomedich-739	111	78	(	(	PUNCT
biomedich-739	111	79	2	2	X
biomedich-739	111	80	)	)	PUNCT
biomedich-739	111	81	epigenetic	epigenetic	ADJ
biomedich-739	111	82	regulation	regulation	NOUN
biomedich-739	111	83	of	of	ADP
biomedich-739	111	84	col1a1	col1a1	NOUN
biomedich-739	111	85	occurs	occur	VERB
biomedich-739	111	86	in	in	ADP
biomedich-739	111	87	some	some	DET
biomedich-739	111	88	diseases	disease	NOUN
biomedich-739	111	89	,	,	PUNCT
biomedich-739	111	90	especially	especially	ADV
biomedich-739	111	91	found	find	VERB
biomedich-739	111	92	at	at	ADP
biomedich-739	111	93	the	the	DET
biomedich-739	111	94	transcription	transcription	NOUN
biomedich-739	111	95	level	level	NOUN
biomedich-739	111	96	which	which	PRON
biomedich-739	111	97	states	state	VERB
biomedich-739	111	98	that	that	SCONJ
biomedich-739	111	99	the	the	DET
biomedich-739	111	100	tgfβ	tgfβ	ADJ
biomedich-739	111	101	pathway	pathway	NOUN
biomedich-739	111	102	plays	play	VERB
biomedich-739	111	103	an	an	DET
biomedich-739	111	104	important	important	ADJ
biomedich-739	111	105	role	role	NOUN
biomedich-739	111	106	,	,	PUNCT
biomedich-739	111	107	especially	especially	ADV
biomedich-739	111	108	through	through	ADP
biomedich-739	111	109	the	the	DET
biomedich-739	111	110	regulation	regulation	NOUN
biomedich-739	111	111	of	of	ADP
biomedich-739	111	112	the	the	DET
biomedich-739	111	113	smad	smad	PROPN
biomedich-739	111	114	transcription	transcription	NOUN
biomedich-739	111	115	factor	factor	NOUN
biomedich-739	111	116	which	which	PRON
biomedich-739	111	117	interacts	interact	VERB
biomedich-739	111	118	directly	directly	ADV
biomedich-739	111	119	with	with	ADP
biomedich-739	111	120	col1a1	col1a1	NOUN
biomedich-739	111	121	.	.	PUNCT
biomedich-739	112	1	other	other	ADJ
biomedich-739	112	2	factors	factor	NOUN
biomedich-739	112	3	known	know	VERB
biomedich-739	112	4	to	to	PART
biomedich-739	112	5	play	play	VERB
biomedich-739	112	6	a	a	DET
biomedich-739	112	7	role	role	NOUN
biomedich-739	112	8	in	in	ADP
biomedich-739	112	9	the	the	DET
biomedich-739	112	10	transcription	transcription	NOUN
biomedich-739	112	11	process	process	NOUN
biomedich-739	112	12	of	of	ADP
biomedich-739	112	13	col1a1	col1a1	NOUN
biomedich-739	112	14	are	be	AUX
biomedich-739	112	15	nf	nf	ADJ
biomedich-739	112	16	-	-	PUNCT
biomedich-739	112	17	κb	κb	NOUN
biomedich-739	112	18	,	,	PUNCT
biomedich-739	112	19	ap2	ap2	PROPN
biomedich-739	112	20	,	,	PUNCT
biomedich-739	112	21	and	and	CCONJ
biomedich-739	112	22	nr4a1	nr4a1	PROPN
biomedich-739	112	23	.	.	PUNCT
biomedich-739	113	1	meanwhile	meanwhile	ADV
biomedich-739	113	2	,	,	PUNCT
biomedich-739	113	3	the	the	DET
biomedich-739	113	4	involvement	involvement	NOUN
biomedich-739	113	5	of	of	ADP
biomedich-739	113	6	other	other	ADJ
biomedich-739	113	7	transcription	transcription	NOUN
biomedich-739	113	8	factors	factor	NOUN
biomedich-739	113	9	such	such	ADJ
biomedich-739	113	10	as	as	ADP
biomedich-739	113	11	notch2	notch2	NOUN
biomedich-739	113	12	,	,	PUNCT
biomedich-739	113	13	c	c	NOUN
biomedich-739	113	14	-	-	PUNCT
biomedich-739	113	15	myb	myb	NOUN
biomedich-739	113	16	,	,	PUNCT
biomedich-739	113	17	hif1α	hif1α	PROPN
biomedich-739	113	18	,	,	PUNCT
biomedich-739	113	19	βcatenin	βcatenin	INTJ
biomedich-739	113	20	,	,	PUNCT
biomedich-739	113	21	zeb1	zeb1	PROPN
biomedich-739	113	22	,	,	PUNCT
biomedich-739	113	23	and	and	CCONJ
biomedich-739	113	24	yap	yap	NOUN
biomedich-739	113	25	is	be	AUX
biomedich-739	113	26	still	still	ADV
biomedich-739	113	27	indirect	indirect	ADJ
biomedich-739	113	28	,	,	PUNCT
biomedich-739	113	29	and	and	CCONJ
biomedich-739	113	30	further	further	ADJ
biomedich-739	113	31	research	research	NOUN
biomedich-739	113	32	is	be	AUX
biomedich-739	113	33	needed	need	VERB
biomedich-739	113	34	to	to	PART
biomedich-739	113	35	ascertain	ascertain	VERB
biomedich-739	113	36	whether	whether	SCONJ
biomedich-739	113	37	these	these	DET
biomedich-739	113	38	factors	factor	NOUN
biomedich-739	113	39	specifically	specifically	ADV
biomedich-739	113	40	target	target	VERB
biomedich-739	113	41	col1a1	col1a1	NOUN
biomedich-739	113	42	,	,	PUNCT
biomedich-739	113	43	(	(	PUNCT
biomedich-739	113	44	3	3	X
biomedich-739	113	45	)	)	PUNCT
biomedich-739	113	46	there	there	PRON
biomedich-739	113	47	is	be	VERB
biomedich-739	113	48	col1a1	col1a1	NOUN
biomedich-739	113	49	regulation	regulation	NOUN
biomedich-739	113	50	at	at	ADP
biomedich-739	113	51	the	the	DET
biomedich-739	113	52	post	post	ADJ
biomedich-739	113	53	-	-	ADJ
biomedich-739	113	54	transcription	transcription	NOUN
biomedich-739	113	55	level	level	NOUN
biomedich-739	113	56	,	,	PUNCT
biomedich-739	113	57	namely	namely	ADV
biomedich-739	113	58	the	the	DET
biomedich-739	113	59	regulation	regulation	NOUN
biomedich-739	113	60	of	of	ADP
biomedich-739	113	61	col1a1	col1a1	NOUN
biomedich-739	113	62	mrna	mrna	NOUN
biomedich-739	113	63	by	by	ADP
biomedich-739	113	64	the	the	DET
biomedich-739	113	65	tent5a	tent5a	PROPN
biomedich-739	113	66	gene	gene	NOUN
biomedich-739	113	67	and	and	CCONJ
biomedich-739	113	68	a	a	DET
biomedich-739	113	69	number	number	NOUN
biomedich-739	113	70	of	of	ADP
biomedich-739	113	71	mirnas	mirna	NOUN
biomedich-739	113	72	(	(	PUNCT
biomedich-739	113	73	mir-98	mir-98	NUM
biomedich-739	113	74	,	,	PUNCT
biomedich-739	113	75	mir-126	mir-126	NOUN
biomedich-739	113	76	-	-	PUNCT
biomedich-739	113	77	5p	5p	NUM
biomedich-739	113	78	,	,	PUNCT
biomedich-739	113	79	mir-2185p	mir-2185p	NUM
biomedich-739	113	80	,	,	PUNCT
biomedich-739	113	81	mir-328	mir-328	NOUN
biomedich-739	113	82	-	-	PUNCT
biomedich-739	113	83	3p	3p	NUM
biomedich-739	113	84	,	,	PUNCT
biomedich-739	113	85	mir-338	mir-338	NOUN
biomedich-739	113	86	-	-	PUNCT
biomedich-739	113	87	3p	3p	NUM
biomedich-739	113	88	and	and	CCONJ
biomedich-739	113	89	mir-29b-3p	mir-29b-3p	PROPN
biomedich-739	113	90	)	)	PUNCT
biomedich-739	113	91	,	,	PUNCT
biomedich-739	113	92	(	(	PUNCT
biomedich-739	113	93	4	4	X
biomedich-739	113	94	)	)	PUNCT
biomedich-739	113	95	changes	change	NOUN
biomedich-739	113	96	in	in	ADP
biomedich-739	113	97	post	post	ADJ
biomedich-739	113	98	-	-	ADJ
biomedich-739	113	99	translational	translational	ADJ
biomedich-739	113	100	modification	modification	NOUN
biomedich-739	113	101	of	of	ADP
biomedich-739	113	102	type	type	NOUN
biomedich-739	113	103	i	i	PRON
biomedich-739	113	104	collagen	collagen	NOUN
biomedich-739	113	105	or	or	CCONJ
biomedich-739	113	106	the	the	DET
biomedich-739	113	107	occurrence	occurrence	NOUN
biomedich-739	113	108	of	of	ADP
biomedich-739	113	109	mutations	mutation	NOUN
biomedich-739	113	110	that	that	PRON
biomedich-739	113	111	alter	alter	VERB
biomedich-739	113	112	the	the	DET
biomedich-739	113	113	procollagen	procollagen	NOUN
biomedich-739	113	114	proteolytic	proteolytic	ADJ
biomedich-739	113	115	cleavage	cleavage	NOUN
biomedich-739	113	116	point	point	NOUN
biomedich-739	113	117	,	,	PUNCT
biomedich-739	113	118	and	and	CCONJ
biomedich-739	113	119	(	(	PUNCT
biomedich-739	113	120	5	5	X
biomedich-739	113	121	)	)	PUNCT
biomedich-739	113	122	there	there	PRON
biomedich-739	113	123	is	be	VERB
biomedich-739	113	124	an	an	DET
biomedich-739	113	125	influence	influence	NOUN
biomedich-739	113	126	of	of	ADP
biomedich-739	113	127	several	several	ADJ
biomedich-739	113	128	proteins	protein	NOUN
biomedich-739	113	129	such	such	ADJ
biomedich-739	113	130	as	as	ADP
biomedich-739	113	131	mmp-2	mmp-2	NUM
biomedich-739	113	132	and	and	CCONJ
biomedich-739	113	133	tryptase	tryptase	NOUN
biomedich-739	113	134	-	-	PUNCT
biomedich-739	113	135	β	β	NOUN
biomedich-739	113	136	that	that	PRON
biomedich-739	113	137	have	have	VERB
biomedich-739	113	138	implications	implication	NOUN
biomedich-739	113	139	for	for	ADP
biomedich-739	113	140	the	the	DET
biomedich-739	113	141	regulation	regulation	NOUN
biomedich-739	113	142	of	of	ADP
biomedich-739	113	143	cola1(i	cola1(i	NOUN
biomedich-739	113	144	)	)	PUNCT
biomedich-739	113	145	gene	gene	NOUN
biomedich-739	113	146	expression	expression	NOUN
biomedich-739	113	147	reported	report	VERB
biomedich-739	113	148	to	to	PART
biomedich-739	113	149	be	be	AUX
biomedich-739	113	150	associated	associate	VERB
biomedich-739	113	151	with	with	ADP
biomedich-739	113	152	various	various	ADJ
biomedich-739	113	153	diseases	disease	NOUN
biomedich-739	113	154	(	(	PUNCT
biomedich-739	113	155	devos	devos	PROPN
biomedich-739	113	156	et	et	PROPN
biomedich-739	113	157	al	al	PROPN
biomedich-739	113	158	.	.	PROPN
biomedich-739	113	159	,	,	PUNCT
biomedich-739	113	160	2023	2023	NUM
biomedich-739	113	161	)	)	PUNCT
biomedich-739	113	162	.	.	PUNCT
biomedich-739	114	1	further	further	ADJ
biomedich-739	114	2	research	research	NOUN
biomedich-739	114	3	is	be	AUX
biomedich-739	114	4	needed	need	VERB
biomedich-739	114	5	to	to	PART
biomedich-739	114	6	understand	understand	VERB
biomedich-739	114	7	the	the	DET
biomedich-739	114	8	effect	effect	NOUN
biomedich-739	114	9	of	of	ADP
biomedich-739	114	10	ortosiphon	ortosiphon	ADJ
biomedich-739	114	11	aristatus	aristatus	NOUN
biomedich-739	114	12	on	on	ADP
biomedich-739	114	13	overall	overall	ADJ
biomedich-739	114	14	glucose	glucose	NOUN
biomedich-739	114	15	metabolism	metabolism	NOUN
biomedich-739	114	16	.	.	PUNCT
biomedich-739	115	1	several	several	ADJ
biomedich-739	115	2	studies	study	NOUN
biomedich-739	115	3	have	have	AUX
biomedich-739	115	4	shown	show	VERB
biomedich-739	115	5	the	the	DET
biomedich-739	115	6	potential	potential	NOUN
biomedich-739	115	7	of	of	ADP
biomedich-739	115	8	ortosiphon	ortosiphon	ADJ
biomedich-739	115	9	aristatus	aristatus	NOUN
biomedich-739	115	10	in	in	ADP
biomedich-739	115	11	lowering	lower	VERB
biomedich-739	115	12	blood	blood	NOUN
biomedich-739	115	13	glucose	glucose	NOUN
biomedich-739	115	14	levels	level	NOUN
biomedich-739	115	15	,	,	PUNCT
biomedich-739	115	16	but	but	CCONJ
biomedich-739	115	17	the	the	DET
biomedich-739	115	18	exact	exact	ADJ
biomedich-739	115	19	mechanism	mechanism	NOUN
biomedich-739	115	20	is	be	AUX
biomedich-739	115	21	still	still	ADV
biomedich-739	115	22	unclear	unclear	ADJ
biomedich-739	115	23	.	.	PUNCT
biomedich-739	116	1	the	the	DET
biomedich-739	116	2	results	result	NOUN
biomedich-739	116	3	of	of	ADP
biomedich-739	116	4	the	the	DET
biomedich-739	116	5	statistical	statistical	ADJ
biomedich-739	116	6	test	test	NOUN
biomedich-739	116	7	that	that	PRON
biomedich-739	116	8	did	do	AUX
biomedich-739	116	9	not	not	PART
biomedich-739	116	10	differ	differ	VERB
biomedich-739	116	11	significantly	significantly	ADV
biomedich-739	116	12	also	also	ADV
biomedich-739	116	13	assumed	assume	VERB
biomedich-739	116	14	that	that	SCONJ
biomedich-739	116	15	the	the	DET
biomedich-739	116	16	development	development	NOUN
biomedich-739	116	17	of	of	ADP
biomedich-739	116	18	diabetes	diabetes	NOUN
biomedich-739	116	19	mellitus	mellitus	NOUN
biomedich-739	116	20	was	be	AUX
biomedich-739	116	21	not	not	PART
biomedich-739	116	22	entirely	entirely	ADV
biomedich-739	116	23	in	in	ADP
biomedich-739	116	24	the	the	DET
biomedich-739	116	25	chronic	chronic	ADJ
biomedich-739	116	26	phase	phase	NOUN
biomedich-739	116	27	,	,	PUNCT
biomedich-739	116	28	related	relate	VERB
biomedich-739	116	29	to	to	ADP
biomedich-739	116	30	the	the	DET
biomedich-739	116	31	complex	complex	ADJ
biomedich-739	116	32	and	and	CCONJ
biomedich-739	116	33	long	long	ADJ
biomedich-739	116	34	-	-	PUNCT
biomedich-739	116	35	term	term	NOUN
biomedich-739	116	36	pathomechanism	pathomechanism	NOUN
biomedich-739	116	37	of	of	ADP
biomedich-739	116	38	diabetes	diabetes	NOUN
biomedich-739	116	39	mellitus	mellitus	NOUN
biomedich-739	116	40	.	.	PUNCT
biomedich-739	117	1	conclusions	conclusion	NOUN
biomedich-739	117	2	administration	administration	PROPN
biomedich-739	117	3	of	of	ADP
biomedich-739	117	4	cat	cat	NOUN
biomedich-739	117	5	whisker	whisker	NOUN
biomedich-739	117	6	leaf	leaf	NOUN
biomedich-739	117	7	extract	extract	NOUN
biomedich-739	117	8	(	(	PUNCT
biomedich-739	117	9	ortosiphon	ortosiphon	ADJ
biomedich-739	117	10	aristatus	aristatus	NOUN
biomedich-739	117	11	)	)	PUNCT
biomedich-739	117	12	for	for	ADP
biomedich-739	117	13	14	14	NUM
biomedich-739	117	14	days	day	NOUN
biomedich-739	117	15	was	be	AUX
biomedich-739	117	16	not	not	PART
biomedich-739	117	17	significant	significant	ADJ
biomedich-739	117	18	in	in	ADP
biomedich-739	117	19	increasing	increase	VERB
biomedich-739	117	20	the	the	DET
biomedich-739	117	21	col1a1	col1a1	NOUN
biomedich-739	117	22	expression	expression	NOUN
biomedich-739	117	23	of	of	ADP
biomedich-739	117	24	hyperglycemia	hyperglycemia	NOUN
biomedich-739	117	25	-	-	PUNCT
biomedich-739	117	26	induced	induce	VERB
biomedich-739	117	27	rats	rat	NOUN
biomedich-739	117	28	.	.	PUNCT
biomedich-739	118	1	regarding	regard	VERB
biomedich-739	118	2	the	the	DET
biomedich-739	118	3	expression	expression	NOUN
biomedich-739	118	4	of	of	ADP
biomedich-739	118	5	col1a1	col1a1	NOUN
biomedich-739	118	6	,	,	PUNCT
biomedich-739	118	7	more	more	ADV
biomedich-739	118	8	comprehensive	comprehensive	ADJ
biomedich-739	118	9	research	research	NOUN
biomedich-739	118	10	is	be	AUX
biomedich-739	118	11	needed	need	VERB
biomedich-739	118	12	on	on	ADP
biomedich-739	118	13	the	the	DET
biomedich-739	118	14	molecular	molecular	ADJ
biomedich-739	118	15	processes	process	NOUN
biomedich-739	118	16	involved	involve	VERB
biomedich-739	118	17	in	in	ADP
biomedich-739	118	18	the	the	DET
biomedich-739	118	19	synthesis	synthesis	NOUN
biomedich-739	118	20	of	of	ADP
biomedich-739	118	21	col1a1	col1a1	NOUN
biomedich-739	118	22	,	,	PUNCT
biomedich-739	118	23	by	by	ADP
biomedich-739	118	24	integrating	integrate	VERB
biomedich-739	118	25	various	various	ADJ
biomedich-739	118	26	factors	factor	NOUN
biomedich-739	118	27	aisyah	aisyah	INTJ
biomedich-739	118	28	et	et	PROPN
biomedich-739	118	29	al	al	PROPN
biomedich-739	118	30	.	.	PROPN
biomedich-739	118	31	–	–	PUNCT
biomedich-739	118	32	effect	effect	NOUN
biomedich-739	118	33	of	of	ADP
biomedich-739	118	34	ortosiphon	ortosiphon	ADJ
biomedich-739	118	35	aristatus	aristatus	NOUN
biomedich-739	118	36	on	on	ADP
biomedich-739	118	37	improving	improve	VERB
biomedich-739	118	38	col1a1	col1a1	NOUN
biomedich-739	118	39	expression	expression	NOUN
biomedich-739	118	40	361	361	NUM
biomedich-739	118	41	that	that	PRON
biomedich-739	118	42	are	be	AUX
biomedich-739	118	43	currently	currently	ADV
biomedich-739	118	44	still	still	ADV
biomedich-739	118	45	being	be	AUX
biomedich-739	118	46	carried	carry	VERB
biomedich-739	118	47	out	out	ADP
biomedich-739	118	48	separately	separately	ADV
biomedich-739	118	49	to	to	PART
biomedich-739	118	50	clarify	clarify	VERB
biomedich-739	118	51	the	the	DET
biomedich-739	118	52	potential	potential	NOUN
biomedich-739	118	53	of	of	ADP
biomedich-739	118	54	col1a1	col1a1	NOUN
biomedich-739	118	55	-	-	PUNCT
biomedich-739	118	56	based	base	VERB
biomedich-739	118	57	therapies	therapy	NOUN
biomedich-739	118	58	based	base	VERB
biomedich-739	118	59	on	on	ADP
biomedich-739	118	60	a	a	DET
biomedich-739	118	61	thorough	thorough	ADJ
biomedich-739	118	62	understanding	understanding	NOUN
biomedich-739	118	63	of	of	ADP
biomedich-739	118	64	col1a1	col1a1	NOUN
biomedich-739	118	65	and	and	CCONJ
biomedich-739	118	66	colα1	colα1	PROPN
biomedich-739	118	67	(	(	PUNCT
biomedich-739	118	68	i	i	NOUN
biomedich-739	118	69	)	)	PUNCT
biomedich-739	118	70	regulation	regulation	NOUN
biomedich-739	118	71	.	.	PUNCT
biomedich-739	119	1	acknowledgements	acknowledgement	NOUN
biomedich-739	119	2	:	:	PUNCT
biomedich-739	119	3	authors	author	NOUN
biomedich-739	119	4	would	would	AUX
biomedich-739	119	5	like	like	VERB
biomedich-739	119	6	to	to	PART
biomedich-739	119	7	thank	thank	VERB
biomedich-739	119	8	the	the	DET
biomedich-739	119	9	faculty	faculty	NOUN
biomedich-739	119	10	of	of	ADP
biomedich-739	119	11	medicine	medicine	NOUN
biomedich-739	119	12	,	,	PUNCT
biomedich-739	119	13	universitas	universita	NOUN
biomedich-739	119	14	muhammadiyah	muhammadiyah	ADP
biomedich-739	119	15	surakarta	surakarta	NOUN
biomedich-739	119	16	for	for	ADP
biomedich-739	119	17	the	the	DET
biomedich-739	119	18	support	support	NOUN
biomedich-739	119	19	in	in	ADP
biomedich-739	119	20	implementing	implement	VERB
biomedich-739	119	21	this	this	DET
biomedich-739	119	22	research	research	NOUN
biomedich-739	119	23	and	and	CCONJ
biomedich-739	119	24	to	to	ADP
biomedich-739	119	25	the	the	DET
biomedich-739	119	26	the	the	DET
biomedich-739	119	27	association	association	NOUN
biomedich-739	119	28	of	of	ADP
biomedich-739	119	29	medical	medical	ADJ
biomedich-739	119	30	and	and	CCONJ
biomedich-739	119	31	health	health	NOUN
biomedich-739	119	32	colleges	college	NOUN
biomedich-739	119	33	of	of	ADP
biomedich-739	119	34	muhammadiyah	muhammadiyah	NOUN
biomedich-739	119	35	for	for	ADP
biomedich-739	119	36	the	the	DET
biomedich-739	119	37	financial	financial	ADJ
biomedich-739	119	38	support	support	NOUN
biomedich-739	119	39	.	.	PUNCT
biomedich-739	120	1	authors	author	NOUN
biomedich-739	120	2	’	'	PUNCT
biomedich-739	120	3	contributions	contribution	NOUN
biomedich-739	120	4	:	:	PUNCT
biomedich-739	120	5	riandini	riandini	PROPN
biomedich-739	120	6	aisyah	aisyah	PROPN
biomedich-739	120	7	&	&	CCONJ
biomedich-739	120	8	safari	safari	PROPN
biomedich-739	120	9	wahyu	wahyu	PROPN
biomedich-739	120	10	jatmiko	jatmiko	NOUN
biomedich-739	120	11	designed	design	VERB
biomedich-739	120	12	the	the	DET
biomedich-739	120	13	study	study	NOUN
biomedich-739	120	14	and	and	CCONJ
biomedich-739	120	15	analyzed	analyze	VERB
biomedich-739	120	16	the	the	DET
biomedich-739	120	17	data	datum	NOUN
biomedich-739	120	18	,	,	PUNCT
biomedich-739	120	19	as	as	ADV
biomedich-739	120	20	well	well	ADV
biomedich-739	120	21	as	as	ADP
biomedich-739	120	22	wrote	write	VERB
biomedich-739	120	23	the	the	DET
biomedich-739	120	24	manuscript	manuscript	NOUN
biomedich-739	120	25	.	.	PUNCT
biomedich-739	121	1	erika	erika	PROPN
biomedich-739	121	2	diana	diana	PROPN
biomedich-739	121	3	risanti	risanti	PROPN
biomedich-739	121	4	conceptualized	conceptualize	VERB
biomedich-739	121	5	research	research	NOUN
biomedich-739	121	6	methodologies	methodology	NOUN
biomedich-739	121	7	.	.	PUNCT
biomedich-739	122	1	fatin	fatin	PROPN
biomedich-739	122	2	asfarina	asfarina	PROPN
biomedich-739	122	3	carried	carry	VERB
biomedich-739	122	4	out	out	ADP
biomedich-739	122	5	the	the	DET
biomedich-739	122	6	laboratory	laboratory	NOUN
biomedich-739	122	7	work	work	NOUN
biomedich-739	122	8	under	under	ADP
biomedich-739	122	9	supervision	supervision	NOUN
biomedich-739	122	10	.	.	PUNCT
biomedich-739	123	1	all	all	DET
biomedich-739	123	2	authors	author	NOUN
biomedich-739	123	3	read	read	VERB
biomedich-739	123	4	and	and	CCONJ
biomedich-739	123	5	approved	approve	VERB
biomedich-739	123	6	the	the	DET
biomedich-739	123	7	final	final	ADJ
biomedich-739	123	8	version	version	NOUN
biomedich-739	123	9	of	of	ADP
biomedich-739	123	10	the	the	DET
biomedich-739	123	11	manuscript	manuscript	NOUN
biomedich-739	123	12	.	.	PUNCT
biomedich-739	124	1	competing	compete	VERB
biomedich-739	124	2	interests	interest	NOUN
biomedich-739	124	3	:	:	PUNCT
biomedich-739	124	4	the	the	DET
biomedich-739	124	5	authors	author	NOUN
biomedich-739	124	6	declare	declare	VERB
biomedich-739	124	7	that	that	SCONJ
biomedich-739	124	8	there	there	PRON
biomedich-739	124	9	are	be	VERB
biomedich-739	124	10	no	no	DET
biomedich-739	124	11	competing	compete	VERB
biomedich-739	124	12	interests	interest	NOUN
biomedich-739	124	13	.	.	PUNCT
biomedich-739	125	1	funding	funding	NOUN
biomedich-739	125	2	:	:	PUNCT
biomedich-739	125	3	this	this	DET
biomedich-739	125	4	research	research	NOUN
biomedich-739	125	5	was	be	AUX
biomedich-739	125	6	funded	fund	VERB
biomedich-739	125	7	by	by	ADP
biomedich-739	125	8	the	the	DET
biomedich-739	125	9	association	association	NOUN
biomedich-739	125	10	of	of	ADP
biomedich-739	125	11	medical	medical	ADJ
biomedich-739	125	12	and	and	CCONJ
biomedich-739	125	13	health	health	NOUN
biomedich-739	125	14	colleges	college	NOUN
biomedich-739	125	15	of	of	ADP
biomedich-739	125	16	muhammadiyah	muhammadiyah	NOUN
biomedich-739	125	17	research	research	NOUN
biomedich-739	125	18	grant	grant	NOUN
biomedich-739	125	19	no	no	NOUN
biomedich-739	125	20	.	.	NOUN
biomedich-739	125	21	4602	4602	NUM
biomedich-739	125	22	/	/	SYM
biomedich-739	125	23	d.2	d.2	NOUN
biomedich-739	125	24	-	-	ADJ
biomedich-739	125	25	vii	vii	ADJ
biomedich-739	125	26	/	/	SYM
biomedich-739	125	27	fk	fk	INTJ
biomedich-739	125	28	/	/	SYM
biomedich-739	125	29	ix/2024	ix/2024	PROPN
biomedich-739	125	30	.	.	PROPN
biomedich-739	125	31	references	reference	NOUN
biomedich-739	125	32	arifah	arifah	PROPN
biomedich-739	125	33	,	,	PUNCT
biomedich-739	125	34	f.	f.	PROPN
biomedich-739	125	35	h.	h.	PROPN
biomedich-739	125	36	,	,	PUNCT
biomedich-739	125	37	nugroho	nugroho	PROPN
biomedich-739	125	38	,	,	PUNCT
biomedich-739	125	39	a.	a.	PROPN
biomedich-739	125	40	e.	e.	PROPN
biomedich-739	125	41	,	,	PUNCT
biomedich-739	125	42	rohman	rohman	PROPN
biomedich-739	125	43	,	,	PUNCT
biomedich-739	125	44	a.	a.	PROPN
biomedich-739	125	45	,	,	PUNCT
biomedich-739	125	46	&	&	CCONJ
biomedich-739	125	47	sujarwo	sujarwo	PROPN
biomedich-739	125	48	,	,	PUNCT
biomedich-739	125	49	w.	w.	PROPN
biomedich-739	125	50	(	(	PUNCT
biomedich-739	125	51	2022	2022	NUM
biomedich-739	125	52	)	)	PUNCT
biomedich-739	125	53	.	.	PUNCT
biomedich-739	126	1	a	a	DET
biomedich-739	126	2	review	review	NOUN
biomedich-739	126	3	of	of	ADP
biomedich-739	126	4	medicinal	medicinal	ADJ
biomedich-739	126	5	plants	plant	NOUN
biomedich-739	126	6	for	for	ADP
biomedich-739	126	7	the	the	DET
biomedich-739	126	8	treatment	treatment	NOUN
biomedich-739	126	9	of	of	ADP
biomedich-739	126	10	diabetes	diabetes	NOUN
biomedich-739	126	11	mellitus	mellitus	NOUN
biomedich-739	126	12	:	:	PUNCT
biomedich-739	126	13	the	the	DET
biomedich-739	126	14	case	case	NOUN
biomedich-739	126	15	of	of	ADP
biomedich-739	126	16	indonesia	indonesia	PROPN
biomedich-739	126	17	.	.	PUNCT
biomedich-739	127	1	south	south	ADJ
biomedich-739	127	2	african	african	ADJ
biomedich-739	127	3	journal	journal	NOUN
biomedich-739	127	4	of	of	ADP
biomedich-739	127	5	botany	botany	NOUN
biomedich-739	127	6	,	,	PUNCT
biomedich-739	127	7	149	149	NUM
biomedich-739	127	8	,	,	PUNCT
biomedich-739	127	9	537–558	537–558	NUM
biomedich-739	127	10	.	.	PUNCT
biomedich-739	128	1	https://doi.org/10.1016/j.sajb.2022.06.042	https://doi.org/10.1016/j.sajb.2022.06.042	PROPN
biomedich-739	128	2	cruz	cruz	PROPN
biomedich-739	128	3	,	,	PUNCT
biomedich-739	128	4	b.	b.	PROPN
biomedich-739	128	5	,	,	PUNCT
biomedich-739	128	6	flores	flores	PROPN
biomedich-739	128	7	,	,	PUNCT
biomedich-739	128	8	r.	r.	PROPN
biomedich-739	128	9	j.	j.	PROPN
biomedich-739	128	10	,	,	PUNCT
biomedich-739	128	11	uribe	uribe	PROPN
biomedich-739	128	12	,	,	PUNCT
biomedich-739	128	13	k.	k.	PROPN
biomedich-739	129	1	p.	p.	PROPN
biomedich-739	129	2	,	,	PUNCT
biomedich-739	129	3	espinoza	espinoza	PROPN
biomedich-739	129	4	,	,	PUNCT
biomedich-739	129	5	e.	e.	PROPN
biomedich-739	129	6	j.	j.	PROPN
biomedich-739	129	7	,	,	PUNCT
biomedich-739	129	8	spencer	spencer	PROPN
biomedich-739	129	9	,	,	PUNCT
biomedich-739	129	10	c.	c.	PROPN
biomedich-739	129	11	t.	t.	PROPN
biomedich-739	129	12	,	,	PUNCT
biomedich-739	129	13	serafine	serafine	NOUN
biomedich-739	129	14	,	,	PUNCT
biomedich-739	129	15	k.	k.	PROPN
biomedich-739	129	16	m.	m.	PROPN
biomedich-739	129	17	,	,	PUNCT
biomedich-739	129	18	nazarian	nazarian	PROPN
biomedich-739	129	19	,	,	PUNCT
biomedich-739	129	20	a.	a.	PROPN
biomedich-739	129	21	,	,	PUNCT
biomedich-739	129	22	&	&	CCONJ
biomedich-739	129	23	o’dell	o’dell	PROPN
biomedich-739	129	24	,	,	PUNCT
biomedich-739	129	25	l.	l.	PROPN
biomedich-739	129	26	e.	e.	PROPN
biomedich-739	129	27	(	(	PUNCT
biomedich-739	129	28	2019	2019	NUM
biomedich-739	129	29	)	)	PUNCT
biomedich-739	129	30	.	.	PUNCT
biomedich-739	130	1	insulin	insulin	NOUN
biomedich-739	130	2	modulates	modulate	VERB
biomedich-739	130	3	the	the	DET
biomedich-739	130	4	strong	strong	ADJ
biomedich-739	130	5	reinforcing	reinforcing	ADJ
biomedich-739	130	6	effects	effect	NOUN
biomedich-739	130	7	of	of	ADP
biomedich-739	130	8	nicotine	nicotine	NOUN
biomedich-739	130	9	and	and	CCONJ
biomedich-739	130	10	changes	change	NOUN
biomedich-739	130	11	in	in	ADP
biomedich-739	130	12	insulin	insulin	NOUN
biomedich-739	130	13	biomarkers	biomarker	NOUN
biomedich-739	130	14	in	in	ADP
biomedich-739	130	15	a	a	DET
biomedich-739	130	16	rodent	rodent	ADJ
biomedich-739	130	17	model	model	NOUN
biomedich-739	130	18	of	of	ADP
biomedich-739	130	19	diabetes	diabetes	NOUN
biomedich-739	130	20	.	.	PUNCT
biomedich-739	131	1	neuropsychopharmacology	neuropsychopharmacology	NOUN
biomedich-739	131	2	,	,	PUNCT
biomedich-739	131	3	44(6	44(6	PROPN
biomedich-739	131	4	)	)	PUNCT
biomedich-739	131	5	,	,	PUNCT
biomedich-739	131	6	1141–1151	1141–1151	NUM
biomedich-739	131	7	.	.	PUNCT
biomedich-739	131	8	https://doi.org/10.1038/s41386-018-0306-3	https://doi.org/10.1038/s41386-018-0306-3	NUM
biomedich-739	131	9	devos	devos	PROPN
biomedich-739	131	10	,	,	PUNCT
biomedich-739	131	11	h.	h.	PROPN
biomedich-739	131	12	,	,	PUNCT
biomedich-739	131	13	zoidakis	zoidakis	PROPN
biomedich-739	131	14	,	,	PUNCT
biomedich-739	131	15	j.	j.	PROPN
biomedich-739	131	16	,	,	PUNCT
biomedich-739	131	17	roubelakis	roubelaki	NOUN
biomedich-739	131	18	,	,	PUNCT
biomedich-739	131	19	m.	m.	NOUN
biomedich-739	131	20	g.	g.	PROPN
biomedich-739	131	21	,	,	PUNCT
biomedich-739	131	22	latosinska	latosinska	PROPN
biomedich-739	131	23	,	,	PUNCT
biomedich-739	131	24	a.	a.	NOUN
biomedich-739	131	25	,	,	PUNCT
biomedich-739	131	26	&	&	CCONJ
biomedich-739	131	27	vlahou	vlahou	PROPN
biomedich-739	131	28	,	,	PUNCT
biomedich-739	131	29	a.	a.	NOUN
biomedich-739	131	30	(	(	PUNCT
biomedich-739	131	31	2023	2023	NUM
biomedich-739	131	32	)	)	PUNCT
biomedich-739	131	33	.	.	PUNCT
biomedich-739	132	1	reviewing	review	VERB
biomedich-739	132	2	the	the	DET
biomedich-739	132	3	regulators	regulator	NOUN
biomedich-739	132	4	of	of	ADP
biomedich-739	132	5	col1a1	col1a1	PROPN
biomedich-739	132	6	.	.	PUNCT
biomedich-739	133	1	international	international	ADJ
biomedich-739	133	2	journal	journal	NOUN
biomedich-739	133	3	of	of	ADP
biomedich-739	133	4	molecular	molecular	ADJ
biomedich-739	133	5	sciences	science	NOUN
biomedich-739	133	6	,	,	PUNCT
biomedich-739	133	7	24(12	24(12	NUM
biomedich-739	133	8	)	)	PUNCT
biomedich-739	133	9	,	,	PUNCT
biomedich-739	133	10	10004	10004	NUM
biomedich-739	133	11	.	.	PUNCT
biomedich-739	134	1	https://doi.org/10.3390/ijms241210004	https://doi.org/10.3390/ijms241210004	PROPN
biomedich-739	134	2	harijanto	harijanto	PROPN
biomedich-739	134	3	,	,	PUNCT
biomedich-739	134	4	e.	e.	PROPN
biomedich-739	134	5	a.	a.	PROPN
biomedich-739	134	6	,	,	PUNCT
biomedich-739	134	7	&	&	CCONJ
biomedich-739	134	8	dewajanti	dewajanti	PROPN
biomedich-739	134	9	,	,	PUNCT
biomedich-739	134	10	a.	a.	NOUN
biomedich-739	134	11	m.	m.	NOUN
biomedich-739	134	12	(	(	PUNCT
biomedich-739	134	13	2017	2017	NUM
biomedich-739	134	14	)	)	PUNCT
biomedich-739	134	15	.	.	PUNCT
biomedich-739	135	1	optimalisasi	optimalisasi	PROPN
biomedich-739	135	2	pemberian	pemberian	PROPN
biomedich-739	135	3	streptozotocin	streptozotocin	PROPN
biomedich-739	135	4	beberapa	beberapa	PROPN
biomedich-739	135	5	dosis	dosis	PROPN
biomedich-739	135	6	terhadap	terhadap	PROPN
biomedich-739	135	7	peningkatan	peningkatan	PROPN
biomedich-739	135	8	kadar	kadar	PROPN
biomedich-739	135	9	gula	gula	PROPN
biomedich-739	135	10	darah	darah	PROPN
biomedich-739	135	11	tikus	tikus	PROPN
biomedich-739	135	12	sprague	sprague	PROPN
biomedich-739	135	13	dawley	dawley	PROPN
biomedich-739	135	14	.	.	PUNCT
biomedich-739	136	1	j.	j.	PROPN
biomedich-739	136	2	kedokt	kedokt	PROPN
biomedich-739	136	3	meditek	meditek	PROPN
biomedich-739	136	4	,	,	PUNCT
biomedich-739	136	5	23(63	23(63	PROPN
biomedich-739	136	6	)	)	PUNCT
biomedich-739	136	7	,	,	PUNCT
biomedich-739	136	8	12	12	NUM
biomedich-739	136	9	-	-	SYM
biomedich-739	136	10	18	18	NUM
biomedich-739	136	11	.	.	PUNCT
biomedich-739	137	1	https://doi.org/10.36452/jkdoktmeditek.v23i63.1559	https://doi.org/10.36452/jkdoktmeditek.v23i63.1559	PROPN
biomedich-739	137	2	khan	khan	PROPN
biomedich-739	137	3	,	,	PUNCT
biomedich-739	137	4	m.	m.	PROPN
biomedich-739	137	5	a.	a.	PROPN
biomedich-739	137	6	b.	b.	PROPN
biomedich-739	137	7	,	,	PUNCT
biomedich-739	137	8	hashim	hashim	PROPN
biomedich-739	137	9	,	,	PUNCT
biomedich-739	137	10	m.	m.	PROPN
biomedich-739	137	11	j.	j.	PROPN
biomedich-739	137	12	,	,	PUNCT
biomedich-739	137	13	king	king	PROPN
biomedich-739	137	14	,	,	PUNCT
biomedich-739	137	15	j.	j.	PROPN
biomedich-739	137	16	k.	k.	PROPN
biomedich-739	137	17	,	,	PUNCT
biomedich-739	137	18	govender	govender	PROPN
biomedich-739	137	19	,	,	PUNCT
biomedich-739	137	20	r.	r.	PROPN
biomedich-739	137	21	d.	d.	PROPN
biomedich-739	137	22	,	,	PUNCT
biomedich-739	137	23	mustafa	mustafa	PROPN
biomedich-739	137	24	,	,	PUNCT
biomedich-739	137	25	h.	h.	PROPN
biomedich-739	137	26	,	,	PUNCT
biomedich-739	137	27	&	&	CCONJ
biomedich-739	137	28	al	al	PROPN
biomedich-739	137	29	kaabi	kaabi	PROPN
biomedich-739	137	30	,	,	PUNCT
biomedich-739	137	31	j.	j.	PROPN
biomedich-739	137	32	(	(	PUNCT
biomedich-739	137	33	2019	2019	NUM
biomedich-739	137	34	)	)	PUNCT
biomedich-739	137	35	.	.	PUNCT
biomedich-739	138	1	epidemiology	epidemiology	NOUN
biomedich-739	138	2	of	of	ADP
biomedich-739	138	3	type	type	NOUN
biomedich-739	138	4	2	2	NUM
biomedich-739	138	5	diabetes	diabetes	NOUN
biomedich-739	138	6	–	–	PUNCT
biomedich-739	138	7	global	global	ADJ
biomedich-739	138	8	burden	burden	NOUN
biomedich-739	138	9	of	of	ADP
biomedich-739	138	10	disease	disease	NOUN
biomedich-739	138	11	and	and	CCONJ
biomedich-739	138	12	forecasted	forecast	VERB
biomedich-739	138	13	trends	trend	NOUN
biomedich-739	138	14	:	:	PUNCT
biomedich-739	138	15	journal	journal	NOUN
biomedich-739	138	16	of	of	ADP
biomedich-739	138	17	epidemiology	epidemiology	NOUN
biomedich-739	138	18	and	and	CCONJ
biomedich-739	138	19	global	global	ADJ
biomedich-739	138	20	health	health	NOUN
biomedich-739	138	21	,	,	PUNCT
biomedich-739	138	22	10(1	10(1	NUM
biomedich-739	138	23	)	)	PUNCT
biomedich-739	138	24	,	,	PUNCT
biomedich-739	138	25	107	107	NUM
biomedich-739	138	26	.	.	PUNCT
biomedich-739	139	1	https://doi.org/10.2991/jegh.k.191028.001	https://doi.org/10.2991/jegh.k.191028.001	PROPN
biomedich-739	139	2	lin	lin	PROPN
biomedich-739	139	3	,	,	PUNCT
biomedich-739	139	4	g.	g.	PROPN
biomedich-739	139	5	,	,	PUNCT
biomedich-739	139	6	wan	wan	PROPN
biomedich-739	139	7	,	,	PUNCT
biomedich-739	139	8	x.	x.	PROPN
biomedich-739	139	9	,	,	PUNCT
biomedich-739	139	10	liu	liu	PROPN
biomedich-739	139	11	,	,	PUNCT
biomedich-739	139	12	d.	d.	PROPN
biomedich-739	139	13	,	,	PUNCT
biomedich-739	139	14	wen	wen	PROPN
biomedich-739	139	15	,	,	PUNCT
biomedich-739	139	16	y.	y.	PROPN
biomedich-739	139	17	,	,	PUNCT
biomedich-739	139	18	yang	yang	PROPN
biomedich-739	139	19	,	,	PUNCT
biomedich-739	139	20	c.	c.	PROPN
biomedich-739	139	21	,	,	PUNCT
biomedich-739	139	22	&	&	CCONJ
biomedich-739	139	23	zhao	zhao	PROPN
biomedich-739	139	24	,	,	PUNCT
biomedich-739	139	25	c.	c.	PROPN
biomedich-739	139	26	(	(	PUNCT
biomedich-739	139	27	2021	2021	NUM
biomedich-739	139	28	)	)	PUNCT
biomedich-739	139	29	.	.	PUNCT
biomedich-739	140	1	col1a1	col1a1	NOUN
biomedich-739	140	2	as	as	ADP
biomedich-739	140	3	a	a	DET
biomedich-739	140	4	potential	potential	ADJ
biomedich-739	140	5	new	new	ADJ
biomedich-739	140	6	biomarker	biomarker	NOUN
biomedich-739	140	7	and	and	CCONJ
biomedich-739	140	8	therapeutic	therapeutic	ADJ
biomedich-739	140	9	target	target	NOUN
biomedich-739	140	10	for	for	ADP
biomedich-739	140	11	type	type	NOUN
biomedich-739	140	12	2	2	NUM
biomedich-739	140	13	diabetes	diabetes	NOUN
biomedich-739	140	14	.	.	PUNCT
biomedich-739	141	1	pharmacological	pharmacological	ADJ
biomedich-739	141	2	research	research	NOUN
biomedich-739	141	3	,	,	PUNCT
biomedich-739	141	4	165	165	NUM
biomedich-739	141	5	,	,	PUNCT
biomedich-739	141	6	105436	105436	NUM
biomedich-739	141	7	.	.	PUNCT
biomedich-739	142	1	https://doi.org/10.1016/j.phrs.2021.105436	https://doi.org/10.1016/j.phrs.2021.105436	PROPN
biomedich-739	142	2	maulana	maulana	PROPN
biomedich-739	142	3	,	,	PUNCT
biomedich-739	142	4	f.	f.	PROPN
biomedich-739	142	5	,	,	PUNCT
biomedich-739	142	6	muhammad	muhammad	PROPN
biomedich-739	142	7	,	,	PUNCT
biomedich-739	142	8	a.	a.	NOUN
biomedich-739	142	9	a.	a.	PROPN
biomedich-739	142	10	,	,	PUNCT
biomedich-739	142	11	umar	umar	PROPN
biomedich-739	142	12	,	,	PUNCT
biomedich-739	142	13	a.	a.	PROPN
biomedich-739	142	14	,	,	PUNCT
biomedich-739	142	15	mahendra	mahendra	PROPN
biomedich-739	142	16	,	,	PUNCT
biomedich-739	142	17	f.	f.	PROPN
biomedich-739	142	18	r.	r.	PROPN
biomedich-739	142	19	,	,	PUNCT
biomedich-739	142	20	musthofa	musthofa	PROPN
biomedich-739	142	21	,	,	PUNCT
biomedich-739	142	22	m.	m.	NOUN
biomedich-739	142	23	,	,	PUNCT
biomedich-739	142	24	&	&	CCONJ
biomedich-739	142	25	nurcholis	nurcholis	PROPN
biomedich-739	142	26	,	,	PUNCT
biomedich-739	142	27	w.	w.	NOUN
biomedich-739	142	28	(	(	PUNCT
biomedich-739	142	29	2022	2022	NUM
biomedich-739	142	30	)	)	PUNCT
biomedich-739	142	31	.	.	PUNCT
biomedich-739	143	1	profiling	profile	VERB
biomedich-739	143	2	metabolites	metabolite	NOUN
biomedich-739	143	3	through	through	ADP
biomedich-739	143	4	chemometric	chemometric	ADJ
biomedich-739	143	5	analysis	analysis	NOUN
biomedich-739	143	6	in	in	ADP
biomedich-739	143	7	orthosiphon	orthosiphon	ADJ
biomedich-739	143	8	aristatus	aristatus	NOUN
biomedich-739	143	9	extracts	extract	NOUN
biomedich-739	143	10	as	as	ADP
biomedich-739	143	11	α	α	NOUN
biomedich-739	143	12	-	-	ADJ
biomedich-739	143	13	glucosidase	glucosidase	ADJ
biomedich-739	143	14	inhibitory	inhibitory	ADJ
biomedich-739	143	15	activity	activity	NOUN
biomedich-739	143	16	and	and	CCONJ
biomedich-739	143	17	in	in	ADP
biomedich-739	143	18	silico	silico	NOUN
biomedich-739	143	19	molecular	molecular	ADJ
biomedich-739	143	20	docking	docking	NOUN
biomedich-739	143	21	.	.	PUNCT
biomedich-739	144	1	indonesian	indonesian	ADJ
biomedich-739	144	2	journal	journal	PROPN
biomedich-739	144	3	of	of	ADP
biomedich-739	144	4	chemistry	chemistry	NOUN
biomedich-739	144	5	,	,	PUNCT
biomedich-739	144	6	22(1	22(1	NUM
biomedich-739	144	7	)	)	PUNCT
biomedich-739	144	8	,	,	PUNCT
biomedich-739	144	9	501	501	NUM
biomedich-739	144	10	.	.	PUNCT
biomedich-739	145	1	https://doi.org/10.22146/ijc.71334	https://doi.org/10.22146/ijc.71334	PROPN
biomedich-739	145	2	munjiati	munjiati	PROPN
biomedich-739	145	3	,	,	PUNCT
biomedich-739	145	4	n.	n.	PROPN
biomedich-739	145	5	e.	e.	PROPN
biomedich-739	145	6	(	(	PUNCT
biomedich-739	145	7	2021	2021	NUM
biomedich-739	145	8	)	)	PUNCT
biomedich-739	145	9	.	.	PUNCT
biomedich-739	146	1	pengaruh	pengaruh	PROPN
biomedich-739	146	2	pemberian	pemberian	PROPN
biomedich-739	146	3	streptozotocin	streptozotocin	PROPN
biomedich-739	146	4	dosis	dosis	PROPN
biomedich-739	146	5	tunggal	tunggal	PROPN
biomedich-739	146	6	terhadap	terhadap	PROPN
biomedich-739	146	7	kadar	kadar	PROPN
biomedich-739	146	8	glukosa	glukosa	PROPN
biomedich-739	146	9	tikus	tikus	PROPN
biomedich-739	146	10	wistar	wistar	PROPN
biomedich-739	146	11	(	(	PUNCT
biomedich-739	146	12	rattus	rattus	PROPN
biomedich-739	146	13	norvegicus	norvegicus	PROPN
biomedich-739	146	14	)	)	PUNCT
biomedich-739	146	15	.	.	PUNCT
biomedich-739	147	1	meditory	meditory	NOUN
biomedich-739	147	2	 	 	SPACE
biomedich-739	147	3	:	:	PUNCT
biomedich-739	147	4	the	the	DET
biomedich-739	147	5	journal	journal	NOUN
biomedich-739	147	6	of	of	ADP
biomedich-739	147	7	medical	medical	ADJ
biomedich-739	147	8	laboratory	laboratory	NOUN
biomedich-739	147	9	,	,	PUNCT
biomedich-739	147	10	9(1	9(1	NUM
biomedich-739	147	11	)	)	PUNCT
biomedich-739	147	12	,	,	PUNCT
biomedich-739	147	13	62–67	62–67	NUM
biomedich-739	147	14	.	.	PUNCT
biomedich-739	148	1	https://doi.org/10.33992/m.v9i1.1330	https://doi.org/10.33992/m.v9i1.1330	PROPN
biomedich-739	148	2	ojo	ojo	NOUN
biomedich-739	148	3	,	,	PUNCT
biomedich-739	148	4	o.	o.	NOUN
biomedich-739	148	5	a.	a.	PROPN
biomedich-739	148	6	,	,	PUNCT
biomedich-739	148	7	ibrahim	ibrahim	PROPN
biomedich-739	148	8	,	,	PUNCT
biomedich-739	148	9	h.	h.	PROPN
biomedich-739	148	10	s.	s.	PROPN
biomedich-739	148	11	,	,	PUNCT
biomedich-739	148	12	rotimi	rotimi	PROPN
biomedich-739	148	13	,	,	PUNCT
biomedich-739	148	14	d.	d.	PROPN
biomedich-739	148	15	e.	e.	PROPN
biomedich-739	148	16	,	,	PUNCT
biomedich-739	148	17	ogunlakin	ogunlakin	PROPN
biomedich-739	148	18	,	,	PUNCT
biomedich-739	148	19	a.	a.	PROPN
biomedich-739	148	20	d.	d.	PROPN
biomedich-739	148	21	,	,	PUNCT
biomedich-739	148	22	&	&	CCONJ
biomedich-739	148	23	ojo	ojo	NOUN
biomedich-739	148	24	,	,	PUNCT
biomedich-739	148	25	a.	a.	PROPN
biomedich-739	148	26	b.	b.	PROPN
biomedich-739	148	27	(	(	PUNCT
biomedich-739	148	28	2023	2023	NUM
biomedich-739	148	29	)	)	PUNCT
biomedich-739	148	30	.	.	PUNCT
biomedich-739	149	1	diabetes	diabetes	NOUN
biomedich-739	149	2	mellitus	mellitus	NOUN
biomedich-739	149	3	:	:	PUNCT
biomedich-739	149	4	from	from	ADP
biomedich-739	149	5	molecular	molecular	ADJ
biomedich-739	149	6	mechanism	mechanism	NOUN
biomedich-739	149	7	to	to	ADP
biomedich-739	149	8	pathophysiology	pathophysiology	NOUN
biomedich-739	149	9	and	and	CCONJ
biomedich-739	149	10	pharmacology	pharmacology	NOUN
biomedich-739	149	11	.	.	PUNCT
biomedich-739	150	1	medicine	medicine	NOUN
biomedich-739	150	2	in	in	ADP
biomedich-739	150	3	novel	novel	ADJ
biomedich-739	150	4	technology	technology	NOUN
biomedich-739	150	5	and	and	CCONJ
biomedich-739	150	6	devices	device	NOUN
biomedich-739	150	7	,	,	PUNCT
biomedich-739	150	8	19	19	NUM
biomedich-739	150	9	,	,	PUNCT
biomedich-739	150	10	100247	100247	NUM
biomedich-739	150	11	.	.	PUNCT
biomedich-739	151	1	https://doi.org/10.1016/j.medntd.2023.100247	https://doi.org/10.1016/j.medntd.2023.100247	PROPN
biomedich-739	151	2	septiana	septiana	PROPN
biomedich-739	151	3	,	,	PUNCT
biomedich-739	151	4	e.	e.	PROPN
biomedich-739	151	5	,	,	PUNCT
biomedich-739	151	6	rizka	rizka	PROPN
biomedich-739	151	7	,	,	PUNCT
biomedich-739	151	8	n.	n.	NOUN
biomedich-739	151	9	m.	m.	NOUN
biomedich-739	151	10	,	,	PUNCT
biomedich-739	151	11	yadi	yadi	NOUN
biomedich-739	151	12	,	,	PUNCT
biomedich-739	151	13	y.	y.	PROPN
biomedich-739	151	14	,	,	PUNCT
biomedich-739	151	15	&	&	CCONJ
biomedich-739	151	16	simanjuntak	simanjuntak	PROPN
biomedich-739	151	17	,	,	PUNCT
biomedich-739	151	18	p.	p.	NOUN
biomedich-739	151	19	(	(	PUNCT
biomedich-739	151	20	2021	2021	NUM
biomedich-739	151	21	)	)	PUNCT
biomedich-739	151	22	.	.	PUNCT
biomedich-739	152	1	antidiabetic	antidiabetic	ADJ
biomedich-739	152	2	activity	activity	NOUN
biomedich-739	152	3	of	of	ADP
biomedich-739	152	4	extract	extract	NOUN
biomedich-739	152	5	combination	combination	NOUN
biomedich-739	152	6	of	of	ADP
biomedich-739	152	7	orthosiphon	orthosiphon	ADJ
biomedich-739	152	8	aristatus	aristatus	NOUN
biomedich-739	152	9	and	and	CCONJ
biomedich-739	152	10	oryza	oryza	PROPN
biomedich-739	152	11	sativa	sativa	PROPN
biomedich-739	152	12	l.	l.	PROPN
biomedich-739	152	13	var	var	PROPN
biomedich-739	152	14	glutinosa	glutinosa	PROPN
biomedich-739	152	15	.	.	PUNCT
biomedich-739	153	1	borneo	borneo	PROPN
biomedich-739	153	2	journal	journal	PROPN
biomedich-739	153	3	of	of	ADP
biomedich-739	153	4	pharmacy	pharmacy	NOUN
biomedich-739	153	5	,	,	PUNCT
biomedich-739	153	6	4(3	4(3	NUM
biomedich-739	153	7	)	)	PUNCT
biomedich-739	153	8	,	,	PUNCT
biomedich-739	153	9	202–209	202–209	NUM
biomedich-739	153	10	.	.	PUNCT
biomedich-739	154	1	https://doi.org/10.33084/bjop.v4i3.2154	https://doi.org/10.33084/bjop.v4i3.2154	VERB
biomedich-739	154	2	thinn	thinn	PROPN
biomedich-739	154	3	,	,	PUNCT
biomedich-739	154	4	n.	n.	PROPN
biomedich-739	154	5	w.	w.	PROPN
biomedich-739	154	6	,	,	PUNCT
biomedich-739	154	7	oo	oo	INTJ
biomedich-739	154	8	,	,	PUNCT
biomedich-739	154	9	z.	z.	PROPN
biomedich-739	154	10	k.	k.	PROPN
biomedich-739	154	11	,	,	PUNCT
biomedich-739	154	12	&	&	CCONJ
biomedich-739	154	13	maw	maw	PROPN
biomedich-739	154	14	,	,	PUNCT
biomedich-739	154	15	s.	s.	PROPN
biomedich-739	154	16	s.	s.	PROPN
biomedich-739	154	17	(	(	PUNCT
biomedich-739	154	18	2018	2018	NUM
biomedich-739	154	19	)	)	PUNCT
biomedich-739	154	20	.	.	PUNCT
biomedich-739	155	1	investigation	investigation	NOUN
biomedich-739	155	2	of	of	ADP
biomedich-739	155	3	hypoglycaemic	hypoglycaemic	ADJ
biomedich-739	155	4	activity	activity	NOUN
biomedich-739	155	5	of	of	ADP
biomedich-739	155	6	some	some	DET
biomedich-739	155	7	myanmar	myanmar	PROPN
biomedich-739	155	8	medicinal	medicinal	ADJ
biomedich-739	155	9	plants	plant	NOUN
biomedich-739	155	10	.	.	PUNCT
biomedich-739	156	1	international	international	ADJ
biomedich-739	156	2	journal	journal	PROPN
biomedich-739	156	3	of	of	ADP
biomedich-739	156	4	technical	technical	PROPN
biomedich-739	156	5	research	research	PROPN
biomedich-739	156	6	&	&	CCONJ
biomedich-739	156	7	science	science	PROPN
biomedich-739	156	8	,	,	PUNCT
biomedich-739	156	9	3(03	3(03	NUM
biomedich-739	156	10	)	)	PUNCT
biomedich-739	156	11	,	,	PUNCT
biomedich-739	156	12	104–108	104–108	NUM
biomedich-739	156	13	.	.	PUNCT
biomedich-739	157	1	https://doi.org/10.30780/ijtrs.v3.i3.2018.011	https://doi.org/10.30780/ijtrs.v3.i3.2018.011	X
biomedich-739	157	2	wahidin	wahidin	ADJ
biomedich-739	157	3	,	,	PUNCT
biomedich-739	157	4	m.	m.	NOUN
biomedich-739	157	5	,	,	PUNCT
biomedich-739	157	6	achadi	achadi	PROPN
biomedich-739	157	7	,	,	PUNCT
biomedich-739	157	8	a.	a.	NOUN
biomedich-739	157	9	,	,	PUNCT
biomedich-739	157	10	besral	besral	NOUN
biomedich-739	157	11	,	,	PUNCT
biomedich-739	157	12	b.	b.	PROPN
biomedich-739	157	13	,	,	PUNCT
biomedich-739	157	14	kosen	kosen	PROPN
biomedich-739	157	15	,	,	PUNCT
biomedich-739	157	16	s.	s.	PROPN
biomedich-739	157	17	,	,	PUNCT
biomedich-739	157	18	nadjib	nadjib	NOUN
biomedich-739	157	19	,	,	PUNCT
biomedich-739	157	20	m.	m.	NOUN
biomedich-739	157	21	,	,	PUNCT
biomedich-739	157	22	nurwahyuni	nurwahyuni	PROPN
biomedich-739	157	23	,	,	PUNCT
biomedich-739	157	24	a.	a.	NOUN
biomedich-739	157	25	,	,	PUNCT
biomedich-739	157	26	ronoatmodjo	ronoatmodjo	PROPN
biomedich-739	157	27	,	,	PUNCT
biomedich-739	157	28	s.	s.	PROPN
biomedich-739	157	29	,	,	PUNCT
biomedich-739	157	30	rahajeng	rahajeng	PROPN
biomedich-739	157	31	,	,	PUNCT
biomedich-739	157	32	e.	e.	PROPN
biomedich-739	157	33	,	,	PUNCT
biomedich-739	157	34	pane	pane	PROPN
biomedich-739	157	35	,	,	PUNCT
biomedich-739	157	36	m.	m.	NOUN
biomedich-739	157	37	,	,	PUNCT
biomedich-739	157	38	&	&	CCONJ
biomedich-739	157	39	kusuma	kusuma	PROPN
biomedich-739	157	40	,	,	PUNCT
biomedich-739	157	41	d.	d.	PROPN
biomedich-739	157	42	(	(	PUNCT
biomedich-739	157	43	2024	2024	NUM
biomedich-739	157	44	)	)	PUNCT
biomedich-739	157	45	.	.	PUNCT
biomedich-739	158	1	projection	projection	NOUN
biomedich-739	158	2	of	of	ADP
biomedich-739	158	3	diabetes	diabetes	NOUN
biomedich-739	158	4	morbidity	morbidity	NOUN
biomedich-739	158	5	and	and	CCONJ
biomedich-739	158	6	mortality	mortality	NOUN
biomedich-739	158	7	till	till	SCONJ
biomedich-739	158	8	2045	2045	NUM
biomedich-739	158	9	in	in	ADP
biomedich-739	158	10	indonesia	indonesia	PROPN
biomedich-739	158	11	based	base	VERB
biomedich-739	158	12	on	on	ADP
biomedich-739	158	13	risk	risk	NOUN
biomedich-739	158	14	factors	factor	NOUN
biomedich-739	158	15	and	and	CCONJ
biomedich-739	158	16	ncd	ncd	PROPN
biomedich-739	158	17	prevention	prevention	PROPN
biomedich-739	158	18	and	and	CCONJ
biomedich-739	158	19	control	control	NOUN
biomedich-739	158	20	programs	program	NOUN
biomedich-739	158	21	.	.	PUNCT
biomedich-739	159	1	scientific	scientific	ADJ
biomedich-739	159	2	reports	report	NOUN
biomedich-739	159	3	,	,	PUNCT
biomedich-739	159	4	14(1	14(1	NUM
biomedich-739	159	5	)	)	PUNCT
biomedich-739	159	6	,	,	PUNCT
biomedich-739	159	7	5424	5424	NUM
biomedich-739	159	8	.	.	PUNCT
biomedich-739	160	1	https://doi.org/10.1038/s41598-024-54563-2	https://doi.org/10.1038/s41598-024-54563-2	PROPN
biomedich-739	160	2	waras	waras	AUX
biomedich-739	160	3	nurcholis	nurcholi	NOUN
biomedich-739	160	4	,	,	PUNCT
biomedich-739	160	5	fachrur	fachrur	PROPN
biomedich-739	160	6	rizal	rizal	PROPN
biomedich-739	160	7	mahendra	mahendra	PROPN
biomedich-739	160	8	,	,	PUNCT
biomedich-739	160	9	milanda	milanda	PROPN
biomedich-739	160	10	fiorella	fiorella	PROPN
biomedich-739	160	11	gultom	gultom	PROPN
biomedich-739	160	12	,	,	PUNCT
biomedich-739	160	13	safira	safira	NOUN
biomedich-739	160	14	khoirunnisa	khoirunnisa	NOUN
biomedich-739	160	15	,	,	PUNCT
biomedich-739	160	16	mayang	mayang	PROPN
biomedich-739	160	17	anggita	anggita	PROPN
biomedich-739	160	18	cahya	cahya	PROPN
biomedich-739	160	19	kurnia	kurnia	PROPN
biomedich-739	160	20	,	,	PUNCT
biomedich-739	160	21	&	&	CCONJ
biomedich-739	160	22	hamdan	hamdan	PROPN
biomedich-739	160	23	hafizh	hafizh	PROPN
biomedich-739	160	24	harahap	harahap	PROPN
biomedich-739	160	25	.	.	PUNCT
biomedich-739	161	1	(	(	PUNCT
biomedich-739	161	2	2022	2022	NUM
biomedich-739	161	3	)	)	PUNCT
biomedich-739	161	4	.	.	PUNCT
biomedich-739	162	1	phytochemical	phytochemical	ADJ
biomedich-739	162	2	,	,	PUNCT
biomedich-739	162	3	antioxidant	antioxidant	ADJ
biomedich-739	162	4	and	and	CCONJ
biomedich-739	162	5	antibacterial	antibacterial	ADJ
biomedich-739	162	6	screening	screening	NOUN
biomedich-739	162	7	of	of	ADP
biomedich-739	162	8	orthosiphon	orthosiphon	PROPN
biomedich-739	162	9	stamineus	stamineus	PROPN
biomedich-739	162	10	leaf	leaf	NOUN
biomedich-739	162	11	extract	extract	VERB
biomedich-739	162	12	two	two	NUM
biomedich-739	162	13	phenotypes	phenotype	NOUN
biomedich-739	162	14	.	.	PUNCT
biomedich-739	163	1	jurnal	jurnal	PROPN
biomedich-739	163	2	jamu	jamu	PROPN
biomedich-739	163	3	indonesia	indonesia	PROPN
biomedich-739	163	4	,	,	PUNCT
biomedich-739	163	5	7(3	7(3	NUM
biomedich-739	163	6	)	)	PUNCT
biomedich-739	163	7	,	,	PUNCT
biomedich-739	163	8	121–129	121–129	NUM
biomedich-739	163	9	.	.	PUNCT
biomedich-739	164	1	https://doi.org/10.29244/jji.v7i3.280	https://doi.org/10.29244/jji.v7i3.280	PROPN
biomedich-739	164	2	weng	weng	PROPN
biomedich-739	164	3	,	,	PUNCT
biomedich-739	164	4	x.	x.	PROPN
biomedich-739	164	5	,	,	PUNCT
biomedich-739	164	6	lin	lin	PROPN
biomedich-739	164	7	,	,	PUNCT
biomedich-739	164	8	d.	d.	PROPN
biomedich-739	164	9	,	,	PUNCT
biomedich-739	164	10	huang	huang	PROPN
biomedich-739	164	11	,	,	PUNCT
biomedich-739	164	12	j.	j.	PROPN
biomedich-739	164	13	t.	t.	PROPN
biomedich-739	164	14	j.	j.	PROPN
biomedich-739	164	15	,	,	PUNCT
biomedich-739	164	16	stimson	stimson	PROPN
biomedich-739	164	17	,	,	PUNCT
biomedich-739	164	18	r.	r.	PROPN
biomedich-739	164	19	h.	h.	PROPN
biomedich-739	164	20	,	,	PUNCT
biomedich-739	164	21	wasserman	wasserman	PROPN
biomedich-739	164	22	,	,	PUNCT
biomedich-739	164	23	d.	d.	PROPN
biomedich-739	164	24	h.	h.	PROPN
biomedich-739	164	25	,	,	PUNCT
biomedich-739	164	26	&	&	CCONJ
biomedich-739	164	27	kang	kang	PROPN
biomedich-739	164	28	,	,	PUNCT
biomedich-739	164	29	l.	l.	PROPN
biomedich-739	164	30	(	(	PUNCT
biomedich-739	164	31	2020	2020	NUM
biomedich-739	164	32	)	)	PUNCT
biomedich-739	164	33	.	.	PUNCT
biomedich-739	165	1	collagen	collagen	NOUN
biomedich-739	165	2	24	24	NUM
biomedich-739	165	3	α1	α1	PROPN
biomedich-739	165	4	is	be	AUX
biomedich-739	165	5	increased	increase	VERB
biomedich-739	165	6	in	in	ADP
biomedich-739	165	7	insulinresistant	insulinresistant	NOUN
biomedich-739	165	8	skeletal	skeletal	ADJ
biomedich-739	165	9	muscle	muscle	NOUN
biomedich-739	165	10	and	and	CCONJ
biomedich-739	165	11	adipose	adipose	ADJ
biomedich-739	165	12	tissue	tissue	NOUN
biomedich-739	165	13	.	.	PUNCT
biomedich-739	166	1	international	international	ADJ
biomedich-739	166	2	journal	journal	NOUN
biomedich-739	166	3	of	of	ADP
biomedich-739	166	4	molecular	molecular	ADJ
biomedich-739	166	5	sciences	science	NOUN
biomedich-739	166	6	,	,	PUNCT
biomedich-739	166	7	21(16	21(16	NOUN
biomedich-739	166	8	)	)	PUNCT
biomedich-739	166	9	,	,	PUNCT
biomedich-739	166	10	5738	5738	NUM
biomedich-739	166	11	.	.	PUNCT
biomedich-739	167	1	https://doi.org/10.3390/ijms21165738	https://doi.org/10.3390/ijms21165738	NOUN
biomedich-739	167	2	this	this	DET
biomedich-739	167	3	page	page	NOUN
biomedich-739	167	4	intentionally	intentionally	ADV
biomedich-739	167	5	left	leave	VERB
biomedich-739	167	6	blank	blank	ADV