id	sid	tid	token	lemma	pos
biomedich-761	1	1	biology	biology	NOUN
biomedich-761	1	2	,	,	PUNCT
biomedich-761	1	3	medicine	medicine	NOUN
biomedich-761	1	4	,	,	PUNCT
biomedich-761	1	5	&	&	CCONJ
biomedich-761	1	6	natural	natural	ADJ
biomedich-761	1	7	product	product	NOUN
biomedich-761	1	8	chemistry	chemistry	NOUN
biomedich-761	1	9	issn	issn	VERB
biomedich-761	1	10	2089	2089	NUM
biomedich-761	1	11	-	-	SYM
biomedich-761	1	12	6514	6514	NUM
biomedich-761	1	13	(	(	PUNCT
biomedich-761	1	14	paper	paper	NOUN
biomedich-761	1	15	)	)	PUNCT
biomedich-761	1	16	volume	volume	NOUN
biomedich-761	1	17	14	14	NUM
biomedich-761	1	18	,	,	PUNCT
biomedich-761	1	19	number	number	NOUN
biomedich-761	1	20	2	2	NUM
biomedich-761	1	21	,	,	PUNCT
biomedich-761	1	22	october	october	PROPN
biomedich-761	1	23	2025	2025	NUM
biomedich-761	1	24	|	|	ADV
biomedich-761	1	25	pages	page	NOUN
biomedich-761	1	26	:	:	PUNCT
biomedich-761	1	27	601	601	NUM
biomedich-761	1	28	-	-	SYM
biomedich-761	1	29	607	607	NUM
biomedich-761	1	30	|	|	ADV
biomedich-761	1	31	doi	doi	NOUN
biomedich-761	1	32	:	:	PUNCT
biomedich-761	1	33	10.14421	10.14421	NUM
biomedich-761	1	34	/	/	SYM
biomedich-761	1	35	biomedich.2025.142.601	biomedich.2025.142.601	PROPN
biomedich-761	1	36	-	-	PUNCT
biomedich-761	1	37	607	607	NUM
biomedich-761	1	38	issn	issn	PROPN
biomedich-761	1	39	2540	2540	NUM
biomedich-761	1	40	-	-	SYM
biomedich-761	1	41	9328	9328	NUM
biomedich-761	1	42	(	(	PUNCT
biomedich-761	1	43	online	online	ADJ
biomedich-761	1	44	)	)	PUNCT
biomedich-761	1	45	physicochemical	physicochemical	ADJ
biomedich-761	1	46	characterization	characterization	NOUN
biomedich-761	1	47	and	and	CCONJ
biomedich-761	1	48	dissolution	dissolution	NOUN
biomedich-761	1	49	enhancement	enhancement	NOUN
biomedich-761	1	50	of	of	ADP
biomedich-761	1	51	mefenamic	mefenamic	ADJ
biomedich-761	1	52	acid	acid	NOUN
biomedich-761	1	53	–	–	PUNCT
biomedich-761	1	54	isonicotinamide	isonicotinamide	NOUN
biomedich-761	1	55	crystalline	crystalline	NOUN
biomedich-761	1	56	solid	solid	ADJ
biomedich-761	1	57	dispersion	dispersion	NOUN
biomedich-761	1	58	indra1	indra1	NOUN
biomedich-761	1	59	,	,	PUNCT
biomedich-761	1	60	*	*	PUNCT
biomedich-761	1	61	,	,	PUNCT
biomedich-761	1	62	nurul	nurul	NOUN
biomedich-761	1	63	apriani1	apriani1	NOUN
biomedich-761	1	64	,	,	PUNCT
biomedich-761	1	65	ade	ade	PROPN
biomedich-761	1	66	yeni	yeni	PROPN
biomedich-761	1	67	aprillia2	aprillia2	PROPN
biomedich-761	1	68	,	,	PUNCT
biomedich-761	1	69	winda	winda	PROPN
biomedich-761	1	70	trisna	trisna	PROPN
biomedich-761	1	71	wulandari2	wulandari2	PROPN
biomedich-761	1	72	,	,	PUNCT
biomedich-761	1	73	gatut	gatut	PROPN
biomedich-761	2	1	ari	ari	PROPN
biomedich-761	2	2	wardani2	wardani2	PROPN
biomedich-761	2	3	,	,	PUNCT
biomedich-761	2	4	firman	firman	PROPN
biomedich-761	2	5	gustaman1	gustaman1	PROPN
biomedich-761	2	6	1department	1department	NUM
biomedich-761	2	7	of	of	ADP
biomedich-761	2	8	pharmaceutics	pharmaceutic	NOUN
biomedich-761	2	9	,	,	PUNCT
biomedich-761	2	10	2department	2department	NUM
biomedich-761	2	11	of	of	ADP
biomedich-761	2	12	pharmacochemistry	pharmacochemistry	NOUN
biomedich-761	2	13	,	,	PUNCT
biomedich-761	2	14	faculty	faculty	NOUN
biomedich-761	2	15	of	of	ADP
biomedich-761	2	16	pharmacy	pharmacy	NOUN
biomedich-761	2	17	,	,	PUNCT
biomedich-761	2	18	universitas	universita	NOUN
biomedich-761	2	19	bakti	bakti	PROPN
biomedich-761	2	20	tunas	tunas	PROPN
biomedich-761	2	21	husada	husada	PROPN
biomedich-761	2	22	,	,	PUNCT
biomedich-761	2	23	jl	jl	PROPN
biomedich-761	2	24	.	.	PUNCT
biomedich-761	3	1	letjen	letjen	PROPN
biomedich-761	3	2	mashudi	mashudi	PROPN
biomedich-761	4	1	no	no	DET
biomedich-761	4	2	20	20	NUM
biomedich-761	4	3	tasikmalaya	tasikmalaya	NOUN
biomedich-761	4	4	46196	46196	NUM
biomedich-761	4	5	,	,	PUNCT
biomedich-761	4	6	tel	tel	PROPN
biomedich-761	4	7	.	.	PUNCT
biomedich-761	4	8	+62	+62	PROPN
biomedich-761	4	9	-	-	PUNCT
biomedich-761	4	10	265	265	NUM
biomedich-761	4	11	-	-	PUNCT
biomedich-761	4	12	334740	334740	NUM
biomedich-761	4	13	,	,	PUNCT
biomedich-761	4	14	indonesia	indonesia	PROPN
biomedich-761	4	15	.	.	PUNCT
biomedich-761	5	1	corresponding	correspond	VERB
biomedich-761	5	2	author	author	NOUN
biomedich-761	5	3	*	*	PROPN
biomedich-761	5	4	indra@universitas-bth.ac.id	indra@universitas-bth.ac.id	PROPN
biomedich-761	5	5	manuscript	manuscript	NOUN
biomedich-761	5	6	received	receive	VERB
biomedich-761	5	7	:	:	PUNCT
biomedich-761	5	8	07	07	NUM
biomedich-761	5	9	april	april	PROPN
biomedich-761	5	10	,	,	PUNCT
biomedich-761	5	11	2025	2025	NUM
biomedich-761	5	12	.	.	PUNCT
biomedich-761	6	1	revision	revision	NOUN
biomedich-761	6	2	accepted	accept	VERB
biomedich-761	6	3	:	:	PUNCT
biomedich-761	6	4	15	15	NUM
biomedich-761	6	5	july	july	NOUN
biomedich-761	6	6	,	,	PUNCT
biomedich-761	6	7	2025	2025	NUM
biomedich-761	6	8	.	.	PUNCT
biomedich-761	7	1	published	publish	VERB
biomedich-761	7	2	:	:	PUNCT
biomedich-761	7	3	01	01	NUM
biomedich-761	7	4	october	october	PROPN
biomedich-761	7	5	,	,	PUNCT
biomedich-761	7	6	2025	2025	NUM
biomedich-761	7	7	.	.	PUNCT
biomedich-761	8	1	abstract	abstract	ADJ
biomedich-761	8	2	poor	poor	ADJ
biomedich-761	8	3	aqueous	aqueous	ADJ
biomedich-761	8	4	solubility	solubility	NOUN
biomedich-761	8	5	limits	limit	VERB
biomedich-761	8	6	the	the	DET
biomedich-761	8	7	bioavailability	bioavailability	NOUN
biomedich-761	8	8	of	of	ADP
biomedich-761	8	9	non	non	ADJ
biomedich-761	8	10	-	-	ADJ
biomedich-761	8	11	steroidal	steroidal	ADJ
biomedich-761	8	12	anti	anti	ADJ
biomedich-761	8	13	-	-	ADJ
biomedich-761	8	14	inflammatory	inflammatory	ADJ
biomedich-761	8	15	drugs	drug	NOUN
biomedich-761	8	16	like	like	ADP
biomedich-761	8	17	mefenamic	mefenamic	ADJ
biomedich-761	8	18	acid	acid	NOUN
biomedich-761	8	19	.	.	PUNCT
biomedich-761	9	1	this	this	DET
biomedich-761	9	2	study	study	NOUN
biomedich-761	9	3	aims	aim	VERB
biomedich-761	9	4	to	to	PART
biomedich-761	9	5	improve	improve	VERB
biomedich-761	9	6	the	the	DET
biomedich-761	9	7	solubility	solubility	NOUN
biomedich-761	9	8	and	and	CCONJ
biomedich-761	9	9	dissolution	dissolution	NOUN
biomedich-761	9	10	of	of	ADP
biomedich-761	9	11	mefenamic	mefenamic	ADJ
biomedich-761	9	12	acid	acid	NOUN
biomedich-761	9	13	through	through	ADP
biomedich-761	9	14	crystalline	crystalline	NOUN
biomedich-761	9	15	solid	solid	ADJ
biomedich-761	9	16	dispersions	dispersion	NOUN
biomedich-761	9	17	using	use	VERB
biomedich-761	9	18	solvent	solvent	ADJ
biomedich-761	9	19	evaporation	evaporation	NOUN
biomedich-761	9	20	and	and	CCONJ
biomedich-761	9	21	co	co	ADJ
biomedich-761	9	22	-	-	ADJ
biomedich-761	9	23	grinding	grinding	ADJ
biomedich-761	9	24	techniques	technique	NOUN
biomedich-761	9	25	with	with	ADP
biomedich-761	9	26	selected	select	VERB
biomedich-761	9	27	co	co	NOUN
biomedich-761	9	28	-	-	NOUN
biomedich-761	9	29	formers	former	NOUN
biomedich-761	9	30	.	.	PUNCT
biomedich-761	10	1	solid	solid	ADJ
biomedich-761	10	2	dispersions	dispersion	NOUN
biomedich-761	10	3	were	be	AUX
biomedich-761	10	4	formulated	formulate	VERB
biomedich-761	10	5	at	at	ADP
biomedich-761	10	6	different	different	ADJ
biomedich-761	10	7	drug	drug	NOUN
biomedich-761	10	8	-	-	PUNCT
biomedich-761	10	9	to	to	ADP
biomedich-761	10	10	-	-	PUNCT
biomedich-761	10	11	co	co	NOUN
biomedich-761	10	12	-	-	ADJ
biomedich-761	10	13	former	former	ADJ
biomedich-761	10	14	ratios	ratio	NOUN
biomedich-761	10	15	(	(	PUNCT
biomedich-761	10	16	1:1	1:1	NUM
biomedich-761	10	17	,	,	PUNCT
biomedich-761	10	18	1:2	1:2	NUM
biomedich-761	10	19	,	,	PUNCT
biomedich-761	10	20	and	and	CCONJ
biomedich-761	10	21	2:1	2:1	NUM
biomedich-761	10	22	)	)	PUNCT
biomedich-761	10	23	and	and	CCONJ
biomedich-761	10	24	characterized	characterize	VERB
biomedich-761	10	25	using	use	VERB
biomedich-761	10	26	differential	differential	NOUN
biomedich-761	10	27	scanning	scan	VERB
biomedich-761	10	28	calorimetry	calorimetry	NOUN
biomedich-761	10	29	,	,	PUNCT
biomedich-761	10	30	fourier	fourier	NOUN
biomedich-761	10	31	-	-	PUNCT
biomedich-761	10	32	transform	transform	NOUN
biomedich-761	10	33	infrared	infrared	ADJ
biomedich-761	10	34	spectroscopy	spectroscopy	NOUN
biomedich-761	10	35	,	,	PUNCT
biomedich-761	10	36	and	and	CCONJ
biomedich-761	10	37	powder	powder	NOUN
biomedich-761	10	38	x	x	NOUN
biomedich-761	10	39	-	-	NOUN
biomedich-761	10	40	ray	ray	NOUN
biomedich-761	10	41	diffraction	diffraction	NOUN
biomedich-761	10	42	.	.	PUNCT
biomedich-761	11	1	dsc	dsc	NOUN
biomedich-761	11	2	results	result	NOUN
biomedich-761	11	3	revealed	reveal	VERB
biomedich-761	11	4	reduced	reduce	VERB
biomedich-761	11	5	crystallinity	crystallinity	NOUN
biomedich-761	11	6	,	,	PUNCT
biomedich-761	11	7	indicated	indicate	VERB
biomedich-761	11	8	by	by	ADP
biomedich-761	11	9	the	the	DET
biomedich-761	11	10	disappearance	disappearance	NOUN
biomedich-761	11	11	of	of	ADP
biomedich-761	11	12	melting	melt	VERB
biomedich-761	11	13	peaks	peak	NOUN
biomedich-761	11	14	and	and	CCONJ
biomedich-761	11	15	the	the	DET
biomedich-761	11	16	appearance	appearance	NOUN
biomedich-761	11	17	of	of	ADP
biomedich-761	11	18	a	a	DET
biomedich-761	11	19	single	single	ADJ
biomedich-761	11	20	glass	glass	NOUN
biomedich-761	11	21	transition	transition	NOUN
biomedich-761	11	22	temperature	temperature	NOUN
biomedich-761	11	23	.	.	PUNCT
biomedich-761	12	1	ftir	ftir	PROPN
biomedich-761	12	2	analysis	analysis	NOUN
biomedich-761	12	3	confirmed	confirm	VERB
biomedich-761	12	4	hydrogen	hydrogen	NOUN
biomedich-761	12	5	bonding	bonding	NOUN
biomedich-761	12	6	between	between	ADP
biomedich-761	12	7	the	the	DET
biomedich-761	12	8	drug	drug	NOUN
biomedich-761	12	9	and	and	CCONJ
biomedich-761	12	10	co	co	NOUN
biomedich-761	12	11	-	-	ADJ
biomedich-761	12	12	former	former	ADJ
biomedich-761	12	13	,	,	PUNCT
biomedich-761	12	14	while	while	SCONJ
biomedich-761	12	15	pxrd	pxrd	ADJ
biomedich-761	12	16	patterns	pattern	NOUN
biomedich-761	12	17	showed	show	VERB
biomedich-761	12	18	a	a	DET
biomedich-761	12	19	loss	loss	NOUN
biomedich-761	12	20	of	of	ADP
biomedich-761	12	21	long	long	ADJ
biomedich-761	12	22	-	-	PUNCT
biomedich-761	12	23	range	range	NOUN
biomedich-761	12	24	order	order	NOUN
biomedich-761	12	25	,	,	PUNCT
biomedich-761	12	26	supporting	support	VERB
biomedich-761	12	27	the	the	DET
biomedich-761	12	28	formation	formation	NOUN
biomedich-761	12	29	of	of	ADP
biomedich-761	12	30	amorphous	amorphous	ADJ
biomedich-761	12	31	phases	phase	NOUN
biomedich-761	12	32	.	.	PUNCT
biomedich-761	13	1	dissolution	dissolution	PROPN
biomedich-761	13	2	testing	testing	NOUN
biomedich-761	13	3	demonstrated	demonstrate	VERB
biomedich-761	13	4	a	a	DET
biomedich-761	13	5	significant	significant	ADJ
biomedich-761	13	6	increase	increase	NOUN
biomedich-761	13	7	in	in	ADP
biomedich-761	13	8	drug	drug	NOUN
biomedich-761	13	9	release	release	NOUN
biomedich-761	13	10	,	,	PUNCT
biomedich-761	13	11	particularly	particularly	ADV
biomedich-761	13	12	in	in	ADP
biomedich-761	13	13	the	the	DET
biomedich-761	13	14	1:2	1:2	NUM
biomedich-761	13	15	formulation	formulation	NOUN
biomedich-761	13	16	,	,	PUNCT
biomedich-761	13	17	which	which	PRON
biomedich-761	13	18	outperformed	outperform	VERB
biomedich-761	13	19	the	the	DET
biomedich-761	13	20	pure	pure	ADJ
biomedich-761	13	21	drug	drug	NOUN
biomedich-761	13	22	and	and	CCONJ
biomedich-761	13	23	other	other	ADJ
biomedich-761	13	24	ratios	ratio	NOUN
biomedich-761	13	25	.	.	PUNCT
biomedich-761	14	1	these	these	DET
biomedich-761	14	2	results	result	NOUN
biomedich-761	14	3	confirm	confirm	VERB
biomedich-761	14	4	that	that	SCONJ
biomedich-761	14	5	the	the	DET
biomedich-761	14	6	choice	choice	NOUN
biomedich-761	14	7	of	of	ADP
biomedich-761	14	8	preparation	preparation	NOUN
biomedich-761	14	9	method	method	NOUN
biomedich-761	14	10	and	and	CCONJ
biomedich-761	14	11	coformer	coformer	NOUN
biomedich-761	14	12	ratio	ratio	NOUN
biomedich-761	14	13	critically	critically	ADV
biomedich-761	14	14	influence	influence	VERB
biomedich-761	14	15	the	the	DET
biomedich-761	14	16	performance	performance	NOUN
biomedich-761	14	17	of	of	ADP
biomedich-761	14	18	solid	solid	ADJ
biomedich-761	14	19	dispersions	dispersion	NOUN
biomedich-761	14	20	.	.	PUNCT
biomedich-761	15	1	this	this	DET
biomedich-761	15	2	study	study	NOUN
biomedich-761	15	3	provides	provide	VERB
biomedich-761	15	4	valuable	valuable	ADJ
biomedich-761	15	5	insights	insight	NOUN
biomedich-761	15	6	into	into	ADP
biomedich-761	15	7	the	the	DET
biomedich-761	15	8	design	design	NOUN
biomedich-761	15	9	of	of	ADP
biomedich-761	15	10	improved	improved	ADJ
biomedich-761	15	11	oral	oral	ADJ
biomedich-761	15	12	formulations	formulation	NOUN
biomedich-761	15	13	for	for	ADP
biomedich-761	15	14	poorly	poorly	ADV
biomedich-761	15	15	soluble	soluble	ADJ
biomedich-761	15	16	drugs	drug	NOUN
biomedich-761	15	17	,	,	PUNCT
biomedich-761	15	18	contributing	contribute	VERB
biomedich-761	15	19	to	to	ADP
biomedich-761	15	20	the	the	DET
biomedich-761	15	21	advancement	advancement	NOUN
biomedich-761	15	22	of	of	ADP
biomedich-761	15	23	pharmaceutical	pharmaceutical	NOUN
biomedich-761	15	24	technology	technology	NOUN
biomedich-761	15	25	.	.	PUNCT
biomedich-761	16	1	keywords	keyword	NOUN
biomedich-761	16	2	:	:	PUNCT
biomedich-761	16	3	crystalline	crystalline	VERB
biomedich-761	16	4	solid	solid	ADJ
biomedich-761	16	5	dispersion	dispersion	NOUN
biomedich-761	16	6	;	;	PUNCT
biomedich-761	16	7	dissolution	dissolution	NOUN
biomedich-761	16	8	improvement	improvement	NOUN
biomedich-761	16	9	;	;	PUNCT
biomedich-761	16	10	drug	drug	NOUN
biomedich-761	16	11	–	–	PUNCT
biomedich-761	16	12	co	co	ADJ
biomedich-761	16	13	-	-	ADJ
biomedich-761	16	14	former	former	ADJ
biomedich-761	16	15	interaction	interaction	NOUN
biomedich-761	16	16	;	;	PUNCT
biomedich-761	16	17	mefenamic	mefenamic	ADJ
biomedich-761	16	18	acid	acid	NOUN
biomedich-761	16	19	.	.	PUNCT
biomedich-761	17	1	introduction	introduction	NOUN
biomedich-761	17	2	oral	oral	ADJ
biomedich-761	17	3	drug	drug	NOUN
biomedich-761	17	4	administration	administration	NOUN
biomedich-761	17	5	remains	remain	VERB
biomedich-761	17	6	the	the	DET
biomedich-761	17	7	most	most	ADV
biomedich-761	17	8	widely	widely	ADV
biomedich-761	17	9	adopted	adopt	VERB
biomedich-761	17	10	route	route	NOUN
biomedich-761	17	11	in	in	ADP
biomedich-761	17	12	clinical	clinical	ADJ
biomedich-761	17	13	practice	practice	NOUN
biomedich-761	17	14	due	due	ADP
biomedich-761	17	15	to	to	ADP
biomedich-761	17	16	its	its	PRON
biomedich-761	17	17	convenience	convenience	NOUN
biomedich-761	17	18	,	,	PUNCT
biomedich-761	17	19	non	non	ADJ
biomedich-761	17	20	-	-	ADJ
biomedich-761	17	21	invasiveness	invasiveness	ADJ
biomedich-761	17	22	,	,	PUNCT
biomedich-761	17	23	cost	cost	NOUN
biomedich-761	17	24	-	-	PUNCT
biomedich-761	17	25	effectiveness	effectiveness	NOUN
biomedich-761	17	26	,	,	PUNCT
biomedich-761	17	27	and	and	CCONJ
biomedich-761	17	28	high	high	ADJ
biomedich-761	17	29	patient	patient	ADJ
biomedich-761	17	30	compliance	compliance	NOUN
biomedich-761	17	31	.	.	PUNCT
biomedich-761	18	1	however	however	ADV
biomedich-761	18	2	,	,	PUNCT
biomedich-761	18	3	the	the	DET
biomedich-761	18	4	therapeutic	therapeutic	ADJ
biomedich-761	18	5	efficacy	efficacy	NOUN
biomedich-761	18	6	of	of	ADP
biomedich-761	18	7	orally	orally	ADV
biomedich-761	18	8	delivered	deliver	VERB
biomedich-761	18	9	drugs	drug	NOUN
biomedich-761	18	10	is	be	AUX
biomedich-761	18	11	critically	critically	ADV
biomedich-761	18	12	dependent	dependent	ADJ
biomedich-761	18	13	on	on	ADP
biomedich-761	18	14	their	their	PRON
biomedich-761	18	15	aqueous	aqueous	ADJ
biomedich-761	18	16	solubility	solubility	NOUN
biomedich-761	18	17	and	and	CCONJ
biomedich-761	18	18	dissolution	dissolution	NOUN
biomedich-761	18	19	rate	rate	NOUN
biomedich-761	18	20	,	,	PUNCT
biomedich-761	18	21	which	which	PRON
biomedich-761	18	22	directly	directly	ADV
biomedich-761	18	23	influence	influence	VERB
biomedich-761	18	24	systemic	systemic	ADJ
biomedich-761	18	25	bioavailability	bioavailability	NOUN
biomedich-761	18	26	.	.	PUNCT
biomedich-761	19	1	a	a	DET
biomedich-761	19	2	large	large	ADJ
biomedich-761	19	3	proportion	proportion	NOUN
biomedich-761	19	4	of	of	ADP
biomedich-761	19	5	both	both	DET
biomedich-761	19	6	established	establish	VERB
biomedich-761	19	7	pharmaceutical	pharmaceutical	ADJ
biomedich-761	19	8	agents	agent	NOUN
biomedich-761	19	9	and	and	CCONJ
biomedich-761	19	10	new	new	ADJ
biomedich-761	19	11	chemical	chemical	NOUN
biomedich-761	19	12	entities	entity	NOUN
biomedich-761	19	13	(	(	PUNCT
biomedich-761	19	14	nces	nce	NOUN
biomedich-761	19	15	)	)	PUNCT
biomedich-761	19	16	fall	fall	VERB
biomedich-761	19	17	into	into	ADP
biomedich-761	19	18	the	the	DET
biomedich-761	19	19	biopharmaceutics	biopharmaceutics	NOUN
biomedich-761	19	20	classification	classification	NOUN
biomedich-761	19	21	system	system	NOUN
biomedich-761	19	22	(	(	PUNCT
biomedich-761	19	23	bcs	bcs	NOUN
biomedich-761	19	24	)	)	PUNCT
biomedich-761	19	25	class	class	NOUN
biomedich-761	19	26	ii	ii	NOUN
biomedich-761	19	27	category	category	NOUN
biomedich-761	19	28	,	,	PUNCT
biomedich-761	19	29	which	which	PRON
biomedich-761	19	30	includes	include	VERB
biomedich-761	19	31	compounds	compound	NOUN
biomedich-761	19	32	with	with	ADP
biomedich-761	19	33	high	high	ADJ
biomedich-761	19	34	membrane	membrane	NOUN
biomedich-761	19	35	permeability	permeability	NOUN
biomedich-761	19	36	but	but	CCONJ
biomedich-761	19	37	poor	poor	ADJ
biomedich-761	19	38	water	water	NOUN
biomedich-761	19	39	solubility	solubility	NOUN
biomedich-761	19	40	(	(	PUNCT
biomedich-761	19	41	mehta	mehta	PROPN
biomedich-761	19	42	et	et	PROPN
biomedich-761	19	43	al	al	PROPN
biomedich-761	19	44	.	.	PROPN
biomedich-761	19	45	,	,	PUNCT
biomedich-761	19	46	2016	2016	NUM
biomedich-761	19	47	;	;	PUNCT
biomedich-761	19	48	patel	patel	PROPN
biomedich-761	19	49	et	et	PROPN
biomedich-761	19	50	al	al	PROPN
biomedich-761	19	51	.	.	PROPN
biomedich-761	19	52	,	,	PUNCT
biomedich-761	19	53	2015	2015	NUM
biomedich-761	19	54	)	)	PUNCT
biomedich-761	19	55	.	.	PUNCT
biomedich-761	20	1	the	the	DET
biomedich-761	20	2	dissolution	dissolution	NOUN
biomedich-761	20	3	-	-	PUNCT
biomedich-761	20	4	limited	limit	VERB
biomedich-761	20	5	absorption	absorption	NOUN
biomedich-761	20	6	of	of	ADP
biomedich-761	20	7	such	such	ADJ
biomedich-761	20	8	drugs	drug	NOUN
biomedich-761	20	9	often	often	ADV
biomedich-761	20	10	results	result	VERB
biomedich-761	20	11	in	in	ADP
biomedich-761	20	12	low	low	ADJ
biomedich-761	20	13	and	and	CCONJ
biomedich-761	20	14	variable	variable	ADJ
biomedich-761	20	15	bioavailability	bioavailability	NOUN
biomedich-761	20	16	,	,	PUNCT
biomedich-761	20	17	necessitating	necessitate	VERB
biomedich-761	20	18	higher	high	ADJ
biomedich-761	20	19	doses	dose	NOUN
biomedich-761	20	20	that	that	PRON
biomedich-761	20	21	may	may	AUX
biomedich-761	20	22	elevate	elevate	VERB
biomedich-761	20	23	the	the	DET
biomedich-761	20	24	risk	risk	NOUN
biomedich-761	20	25	of	of	ADP
biomedich-761	20	26	side	side	NOUN
biomedich-761	20	27	effects	effect	NOUN
biomedich-761	20	28	and	and	CCONJ
biomedich-761	20	29	reduce	reduce	VERB
biomedich-761	20	30	formulation	formulation	NOUN
biomedich-761	20	31	efficiency	efficiency	NOUN
biomedich-761	20	32	.	.	PUNCT
biomedich-761	21	1	mefenamic	mefenamic	ADJ
biomedich-761	21	2	acid	acid	NOUN
biomedich-761	21	3	,	,	PUNCT
biomedich-761	21	4	a	a	DET
biomedich-761	21	5	commonly	commonly	ADV
biomedich-761	21	6	used	use	VERB
biomedich-761	21	7	non	non	ADJ
biomedich-761	21	8	-	-	ADJ
biomedich-761	21	9	steroidal	steroidal	ADJ
biomedich-761	21	10	antiinflammatory	antiinflammatory	NOUN
biomedich-761	21	11	drug	drug	NOUN
biomedich-761	21	12	(	(	PUNCT
biomedich-761	21	13	nsaid	nsaid	PROPN
biomedich-761	21	14	)	)	PUNCT
biomedich-761	21	15	,	,	PUNCT
biomedich-761	21	16	exemplifies	exemplify	VERB
biomedich-761	21	17	these	these	DET
biomedich-761	21	18	challenges	challenge	NOUN
biomedich-761	21	19	.	.	PUNCT
biomedich-761	22	1	despite	despite	SCONJ
biomedich-761	22	2	its	its	PRON
biomedich-761	22	3	therapeutic	therapeutic	ADJ
biomedich-761	22	4	utility	utility	NOUN
biomedich-761	22	5	in	in	ADP
biomedich-761	22	6	treating	treat	VERB
biomedich-761	22	7	pain	pain	NOUN
biomedich-761	22	8	and	and	CCONJ
biomedich-761	22	9	inflammation	inflammation	NOUN
biomedich-761	22	10	,	,	PUNCT
biomedich-761	22	11	mefenamic	mefenamic	ADJ
biomedich-761	22	12	acid	acid	NOUN
biomedich-761	22	13	exhibits	exhibit	VERB
biomedich-761	22	14	limited	limited	ADJ
biomedich-761	22	15	solubility	solubility	NOUN
biomedich-761	22	16	in	in	ADP
biomedich-761	22	17	aqueous	aqueous	ADJ
biomedich-761	22	18	environments	environment	NOUN
biomedich-761	22	19	,	,	PUNCT
biomedich-761	22	20	leading	lead	VERB
biomedich-761	22	21	to	to	ADP
biomedich-761	22	22	erratic	erratic	ADJ
biomedich-761	22	23	absorption	absorption	NOUN
biomedich-761	22	24	profiles	profile	NOUN
biomedich-761	22	25	and	and	CCONJ
biomedich-761	22	26	requiring	require	VERB
biomedich-761	22	27	frequent	frequent	ADJ
biomedich-761	22	28	or	or	CCONJ
biomedich-761	22	29	high	high	ADV
biomedich-761	22	30	-	-	PUNCT
biomedich-761	22	31	dose	dose	NOUN
biomedich-761	22	32	administration	administration	NOUN
biomedich-761	22	33	(	(	PUNCT
biomedich-761	22	34	ghyadh	ghyadh	PROPN
biomedich-761	22	35	&	&	CCONJ
biomedich-761	22	36	al	al	PROPN
biomedich-761	22	37	-	-	PUNCT
biomedich-761	22	38	khedairy	khedairy	PROPN
biomedich-761	22	39	,	,	PUNCT
biomedich-761	22	40	2023	2023	NUM
biomedich-761	22	41	;	;	PUNCT
biomedich-761	22	42	vasanani	vasanani	PROPN
biomedich-761	22	43	et	et	PROPN
biomedich-761	22	44	al	al	PROPN
biomedich-761	22	45	.	.	PROPN
biomedich-761	22	46	,	,	PUNCT
biomedich-761	22	47	2016	2016	NUM
biomedich-761	22	48	)	)	PUNCT
biomedich-761	22	49	.	.	PUNCT
biomedich-761	23	1	these	these	DET
biomedich-761	23	2	limitations	limitation	NOUN
biomedich-761	23	3	not	not	PART
biomedich-761	23	4	only	only	ADV
biomedich-761	23	5	reduce	reduce	VERB
biomedich-761	23	6	patient	patient	ADJ
biomedich-761	23	7	adherence	adherence	NOUN
biomedich-761	23	8	but	but	CCONJ
biomedich-761	23	9	also	also	ADV
biomedich-761	23	10	raise	raise	VERB
biomedich-761	23	11	safety	safety	NOUN
biomedich-761	23	12	concerns	concern	NOUN
biomedich-761	23	13	due	due	ADP
biomedich-761	23	14	to	to	ADP
biomedich-761	23	15	potential	potential	ADJ
biomedich-761	23	16	gastrointestinal	gastrointestinal	ADJ
biomedich-761	23	17	and	and	CCONJ
biomedich-761	23	18	renal	renal	ADJ
biomedich-761	23	19	adverse	adverse	ADJ
biomedich-761	23	20	effects	effect	NOUN
biomedich-761	23	21	(	(	PUNCT
biomedich-761	23	22	pervaiz	pervaiz	PROPN
biomedich-761	23	23	et	et	PROPN
biomedich-761	23	24	al	al	PROPN
biomedich-761	23	25	.	.	PROPN
biomedich-761	23	26	,	,	PUNCT
biomedich-761	23	27	2023	2023	NUM
biomedich-761	23	28	;	;	PUNCT
biomedich-761	23	29	sanas	sanas	PROPN
biomedich-761	23	30	&	&	CCONJ
biomedich-761	23	31	pachpute	pachpute	PROPN
biomedich-761	23	32	,	,	PUNCT
biomedich-761	23	33	2023	2023	NUM
biomedich-761	23	34	)	)	PUNCT
biomedich-761	23	35	.	.	PUNCT
biomedich-761	24	1	several	several	ADJ
biomedich-761	24	2	formulation	formulation	NOUN
biomedich-761	24	3	strategies	strategy	NOUN
biomedich-761	24	4	have	have	AUX
biomedich-761	24	5	been	be	AUX
biomedich-761	24	6	explored	explore	VERB
biomedich-761	24	7	to	to	PART
biomedich-761	24	8	address	address	VERB
biomedich-761	24	9	solubility	solubility	NOUN
biomedich-761	24	10	-	-	PUNCT
biomedich-761	24	11	related	relate	VERB
biomedich-761	24	12	issues	issue	NOUN
biomedich-761	24	13	in	in	ADP
biomedich-761	24	14	bcs	bcs	NOUN
biomedich-761	24	15	class	class	NOUN
biomedich-761	24	16	ii	ii	NOUN
biomedich-761	24	17	drugs	drug	NOUN
biomedich-761	24	18	,	,	PUNCT
biomedich-761	24	19	including	include	VERB
biomedich-761	24	20	particle	particle	NOUN
biomedich-761	24	21	size	size	NOUN
biomedich-761	24	22	reduction	reduction	NOUN
biomedich-761	24	23	,	,	PUNCT
biomedich-761	24	24	lipid	lipid	NOUN
biomedich-761	24	25	-	-	PUNCT
biomedich-761	24	26	based	base	VERB
biomedich-761	24	27	delivery	delivery	NOUN
biomedich-761	24	28	systems	system	NOUN
biomedich-761	24	29	,	,	PUNCT
biomedich-761	24	30	and	and	CCONJ
biomedich-761	24	31	solid	solid	ADJ
biomedich-761	24	32	dispersion	dispersion	NOUN
biomedich-761	24	33	techniques	technique	NOUN
biomedich-761	24	34	(	(	PUNCT
biomedich-761	24	35	doshi	doshi	PROPN
biomedich-761	24	36	et	et	PROPN
biomedich-761	24	37	al	al	PROPN
biomedich-761	24	38	.	.	PROPN
biomedich-761	24	39	,	,	PUNCT
biomedich-761	24	40	2024	2024	NUM
biomedich-761	24	41	;	;	PUNCT
biomedich-761	24	42	fontana	fontana	PROPN
biomedich-761	24	43	et	et	PROPN
biomedich-761	24	44	al	al	PROPN
biomedich-761	24	45	.	.	PROPN
biomedich-761	24	46	,	,	PUNCT
biomedich-761	24	47	2018	2018	NUM
biomedich-761	24	48	)	)	PUNCT
biomedich-761	24	49	.	.	PUNCT
biomedich-761	25	1	among	among	ADP
biomedich-761	25	2	these	these	PRON
biomedich-761	25	3	,	,	PUNCT
biomedich-761	25	4	solid	solid	ADJ
biomedich-761	25	5	dispersion	dispersion	NOUN
biomedich-761	25	6	technology	technology	NOUN
biomedich-761	25	7	has	have	AUX
biomedich-761	25	8	shown	show	VERB
biomedich-761	25	9	significant	significant	ADJ
biomedich-761	25	10	promise	promise	NOUN
biomedich-761	25	11	by	by	ADP
biomedich-761	25	12	enhancing	enhance	VERB
biomedich-761	25	13	drug	drug	NOUN
biomedich-761	25	14	dissolution	dissolution	NOUN
biomedich-761	25	15	through	through	ADP
biomedich-761	25	16	alterations	alteration	NOUN
biomedich-761	25	17	in	in	ADP
biomedich-761	25	18	solidstate	solidstate	PROPN
biomedich-761	25	19	properties	property	NOUN
biomedich-761	25	20	(	(	PUNCT
biomedich-761	25	21	h.	h.	PROPN
biomedich-761	25	22	kumar	kumar	PROPN
biomedich-761	25	23	et	et	PROPN
biomedich-761	25	24	al	al	PROPN
biomedich-761	25	25	.	.	PROPN
biomedich-761	25	26	,	,	PUNCT
biomedich-761	25	27	2022	2022	NUM
biomedich-761	25	28	;	;	PUNCT
biomedich-761	25	29	neeharika	neeharika	PROPN
biomedich-761	25	30	&	&	CCONJ
biomedich-761	25	31	jyothi	jyothi	PROPN
biomedich-761	25	32	,	,	PUNCT
biomedich-761	25	33	2021	2021	NUM
biomedich-761	25	34	)	)	PUNCT
biomedich-761	25	35	.	.	PUNCT
biomedich-761	26	1	by	by	ADP
biomedich-761	26	2	dispersing	disperse	VERB
biomedich-761	26	3	a	a	DET
biomedich-761	26	4	poorly	poorly	ADV
biomedich-761	26	5	soluble	soluble	ADJ
biomedich-761	26	6	drug	drug	NOUN
biomedich-761	26	7	in	in	ADP
biomedich-761	26	8	an	an	DET
biomedich-761	26	9	inert	inert	ADJ
biomedich-761	26	10	carrier	carrier	NOUN
biomedich-761	26	11	matrix	matrix	NOUN
biomedich-761	26	12	,	,	PUNCT
biomedich-761	26	13	this	this	DET
biomedich-761	26	14	approach	approach	NOUN
biomedich-761	26	15	often	often	ADV
biomedich-761	26	16	facilitates	facilitate	VERB
biomedich-761	26	17	reduced	reduce	VERB
biomedich-761	26	18	crystallinity	crystallinity	NOUN
biomedich-761	26	19	or	or	CCONJ
biomedich-761	26	20	complete	complete	ADJ
biomedich-761	26	21	amorphization	amorphization	NOUN
biomedich-761	26	22	of	of	ADP
biomedich-761	26	23	the	the	DET
biomedich-761	26	24	active	active	ADJ
biomedich-761	26	25	pharmaceutical	pharmaceutical	ADJ
biomedich-761	26	26	ingredient	ingredient	NOUN
biomedich-761	26	27	(	(	PUNCT
biomedich-761	26	28	api	api	NOUN
biomedich-761	26	29	)	)	PUNCT
biomedich-761	26	30	,	,	PUNCT
biomedich-761	26	31	thereby	thereby	ADV
biomedich-761	26	32	improving	improve	VERB
biomedich-761	26	33	wettability	wettability	NOUN
biomedich-761	26	34	,	,	PUNCT
biomedich-761	26	35	surface	surface	NOUN
biomedich-761	26	36	area	area	NOUN
biomedich-761	26	37	,	,	PUNCT
biomedich-761	26	38	and	and	CCONJ
biomedich-761	26	39	the	the	DET
biomedich-761	26	40	thermodynamic	thermodynamic	ADJ
biomedich-761	26	41	driving	driving	NOUN
biomedich-761	26	42	force	force	NOUN
biomedich-761	26	43	for	for	ADP
biomedich-761	26	44	dissolution	dissolution	NOUN
biomedich-761	26	45	.	.	PUNCT
biomedich-761	27	1	within	within	ADP
biomedich-761	27	2	the	the	DET
biomedich-761	27	3	spectrum	spectrum	NOUN
biomedich-761	27	4	of	of	ADP
biomedich-761	27	5	solid	solid	ADJ
biomedich-761	27	6	dispersions	dispersion	NOUN
biomedich-761	27	7	,	,	PUNCT
biomedich-761	27	8	crystalline	crystalline	X
biomedich-761	27	9	solid	solid	ADJ
biomedich-761	27	10	dispersions	dispersion	NOUN
biomedich-761	27	11	(	(	PUNCT
biomedich-761	27	12	csds	csds	NOUN
biomedich-761	27	13	)	)	PUNCT
biomedich-761	27	14	represent	represent	VERB
biomedich-761	27	15	an	an	DET
biomedich-761	27	16	underexplored	underexplored	ADJ
biomedich-761	27	17	yet	yet	CCONJ
biomedich-761	27	18	valuable	valuable	ADJ
biomedich-761	27	19	subclass	subclass	NOUN
biomedich-761	27	20	.	.	PUNCT
biomedich-761	28	1	unlike	unlike	ADP
biomedich-761	28	2	amorphous	amorphous	ADJ
biomedich-761	28	3	solid	solid	ADJ
biomedich-761	28	4	dispersions	dispersion	NOUN
biomedich-761	28	5	that	that	PRON
biomedich-761	28	6	eliminate	eliminate	VERB
biomedich-761	28	7	crystallinity	crystallinity	NOUN
biomedich-761	28	8	,	,	PUNCT
biomedich-761	28	9	csds	csd	NOUN
biomedich-761	28	10	retain	retain	VERB
biomedich-761	28	11	partial	partial	ADJ
biomedich-761	28	12	or	or	CCONJ
biomedich-761	28	13	complete	complete	ADJ
biomedich-761	28	14	crystalline	crystalline	NOUN
biomedich-761	28	15	order	order	NOUN
biomedich-761	28	16	while	while	SCONJ
biomedich-761	28	17	achieving	achieve	VERB
biomedich-761	28	18	improved	improved	ADJ
biomedich-761	28	19	dissolution	dissolution	NOUN
biomedich-761	28	20	through	through	ADP
biomedich-761	28	21	spatial	spatial	ADJ
biomedich-761	28	22	distribution	distribution	NOUN
biomedich-761	28	23	and	and	CCONJ
biomedich-761	28	24	drug	drug	NOUN
biomedich-761	28	25	–	–	PUNCT
biomedich-761	28	26	carrier	carrier	NOUN
biomedich-761	28	27	interactions	interaction	NOUN
biomedich-761	28	28	(	(	PUNCT
biomedich-761	28	29	baghel	baghel	X
biomedich-761	28	30	et	et	PROPN
biomedich-761	28	31	al	al	PROPN
biomedich-761	28	32	.	.	PROPN
biomedich-761	28	33	,	,	PUNCT
biomedich-761	28	34	2016	2016	NUM
biomedich-761	28	35	;	;	PUNCT
biomedich-761	28	36	a.	a.	PROPN
biomedich-761	28	37	kumar	kumar	PROPN
biomedich-761	28	38	,	,	PUNCT
biomedich-761	28	39	2017	2017	NUM
biomedich-761	28	40	)	)	PUNCT
biomedich-761	28	41	.	.	PUNCT
biomedich-761	29	1	this	this	PRON
biomedich-761	29	2	https://doi.org/10.14421/biomedich.2025.142.601-607	https://doi.org/10.14421/biomedich.2025.142.601-607	PRON
biomedich-761	29	3	602	602	NUM
biomedich-761	29	4	biology	biology	NOUN
biomedich-761	29	5	,	,	PUNCT
biomedich-761	29	6	medicine	medicine	NOUN
biomedich-761	29	7	,	,	PUNCT
biomedich-761	29	8	&	&	CCONJ
biomedich-761	29	9	natural	natural	ADJ
biomedich-761	29	10	product	product	NOUN
biomedich-761	29	11	chemistry	chemistry	NOUN
biomedich-761	29	12	14	14	NUM
biomedich-761	29	13	(	(	PUNCT
biomedich-761	29	14	2	2	NUM
biomedich-761	29	15	)	)	PUNCT
biomedich-761	29	16	,	,	PUNCT
biomedich-761	29	17	2025	2025	NUM
biomedich-761	29	18	:	:	PUNCT
biomedich-761	29	19	601	601	NUM
biomedich-761	29	20	-	-	SYM
biomedich-761	29	21	607	607	NUM
biomedich-761	29	22	partial	partial	ADJ
biomedich-761	29	23	retention	retention	NOUN
biomedich-761	29	24	of	of	ADP
biomedich-761	29	25	crystallinity	crystallinity	NOUN
biomedich-761	29	26	offers	offer	VERB
biomedich-761	29	27	greater	great	ADJ
biomedich-761	29	28	physical	physical	ADJ
biomedich-761	29	29	stability	stability	NOUN
biomedich-761	29	30	,	,	PUNCT
biomedich-761	29	31	minimizing	minimize	VERB
biomedich-761	29	32	the	the	DET
biomedich-761	29	33	risk	risk	NOUN
biomedich-761	29	34	of	of	ADP
biomedich-761	29	35	recrystallization	recrystallization	NOUN
biomedich-761	29	36	—	—	PUNCT
biomedich-761	29	37	a	a	DET
biomedich-761	29	38	common	common	ADJ
biomedich-761	29	39	drawback	drawback	NOUN
biomedich-761	29	40	of	of	ADP
biomedich-761	29	41	amorphous	amorphous	ADJ
biomedich-761	29	42	systems	system	NOUN
biomedich-761	29	43	(	(	PUNCT
biomedich-761	29	44	babu	babu	PROPN
biomedich-761	29	45	&	&	CCONJ
biomedich-761	29	46	nangia	nangia	PROPN
biomedich-761	29	47	,	,	PUNCT
biomedich-761	29	48	2011	2011	NUM
biomedich-761	29	49	)	)	PUNCT
biomedich-761	29	50	.	.	PUNCT
biomedich-761	30	1	although	although	SCONJ
biomedich-761	30	2	csds	csds	NOUN
biomedich-761	30	3	may	may	AUX
biomedich-761	30	4	not	not	PART
biomedich-761	30	5	always	always	ADV
biomedich-761	30	6	achieve	achieve	VERB
biomedich-761	30	7	the	the	DET
biomedich-761	30	8	same	same	ADJ
biomedich-761	30	9	level	level	NOUN
biomedich-761	30	10	of	of	ADP
biomedich-761	30	11	solubility	solubility	NOUN
biomedich-761	30	12	enhancement	enhancement	NOUN
biomedich-761	30	13	as	as	ADP
biomedich-761	30	14	fully	fully	ADV
biomedich-761	30	15	amorphous	amorphous	ADJ
biomedich-761	30	16	dispersions	dispersion	NOUN
biomedich-761	30	17	,	,	PUNCT
biomedich-761	30	18	they	they	PRON
biomedich-761	30	19	provide	provide	VERB
biomedich-761	30	20	a	a	DET
biomedich-761	30	21	favorable	favorable	ADJ
biomedich-761	30	22	compromise	compromise	NOUN
biomedich-761	30	23	between	between	ADP
biomedich-761	30	24	performance	performance	NOUN
biomedich-761	30	25	and	and	CCONJ
biomedich-761	30	26	shelf	shelf	NOUN
biomedich-761	30	27	stability	stability	NOUN
biomedich-761	30	28	(	(	PUNCT
biomedich-761	30	29	thayyil	thayyil	NOUN
biomedich-761	30	30	et	et	PROPN
biomedich-761	30	31	al	al	PROPN
biomedich-761	30	32	.	.	PROPN
biomedich-761	30	33	,	,	PUNCT
biomedich-761	30	34	2020	2020	NUM
biomedich-761	30	35	)	)	PUNCT
biomedich-761	30	36	.	.	PUNCT
biomedich-761	31	1	the	the	DET
biomedich-761	31	2	choice	choice	NOUN
biomedich-761	31	3	of	of	ADP
biomedich-761	31	4	an	an	DET
biomedich-761	31	5	appropriate	appropriate	ADJ
biomedich-761	31	6	co	co	NOUN
biomedich-761	31	7	-	-	ADJ
biomedich-761	31	8	former	former	ADJ
biomedich-761	31	9	or	or	CCONJ
biomedich-761	31	10	matrix	matrix	NOUN
biomedich-761	31	11	is	be	AUX
biomedich-761	31	12	central	central	ADJ
biomedich-761	31	13	to	to	ADP
biomedich-761	31	14	the	the	DET
biomedich-761	31	15	success	success	NOUN
biomedich-761	31	16	of	of	ADP
biomedich-761	31	17	csds	csds	NOUN
biomedich-761	31	18	.	.	PUNCT
biomedich-761	32	1	while	while	SCONJ
biomedich-761	32	2	polymers	polymer	NOUN
biomedich-761	32	3	like	like	ADP
biomedich-761	32	4	polyvinylpyrrolidone	polyvinylpyrrolidone	PROPN
biomedich-761	32	5	(	(	PUNCT
biomedich-761	32	6	pvp	pvp	NOUN
biomedich-761	32	7	)	)	PUNCT
biomedich-761	32	8	and	and	CCONJ
biomedich-761	32	9	polyethylene	polyethylene	NOUN
biomedich-761	32	10	glycol	glycol	NOUN
biomedich-761	32	11	(	(	PUNCT
biomedich-761	32	12	peg	peg	NOUN
biomedich-761	32	13	)	)	PUNCT
biomedich-761	32	14	are	be	AUX
biomedich-761	32	15	commonly	commonly	ADV
biomedich-761	32	16	used	use	VERB
biomedich-761	32	17	,	,	PUNCT
biomedich-761	32	18	low	low	ADJ
biomedich-761	32	19	-	-	PUNCT
biomedich-761	32	20	molecular	molecular	ADJ
biomedich-761	32	21	-	-	PUNCT
biomedich-761	32	22	weight	weight	NOUN
biomedich-761	32	23	coformers	coformer	NOUN
biomedich-761	32	24	such	such	ADJ
biomedich-761	32	25	as	as	ADP
biomedich-761	32	26	isonicotinamide	isonicotinamide	NOUN
biomedich-761	32	27	(	(	PUNCT
biomedich-761	32	28	ina	ina	PROPN
biomedich-761	32	29	)	)	PUNCT
biomedich-761	32	30	have	have	AUX
biomedich-761	32	31	recently	recently	ADV
biomedich-761	32	32	gained	gain	VERB
biomedich-761	32	33	attention	attention	NOUN
biomedich-761	32	34	due	due	ADP
biomedich-761	32	35	to	to	ADP
biomedich-761	32	36	their	their	PRON
biomedich-761	32	37	capacity	capacity	NOUN
biomedich-761	32	38	for	for	ADP
biomedich-761	32	39	hydrogen	hydrogen	NOUN
biomedich-761	32	40	bonding	bonding	NOUN
biomedich-761	32	41	,	,	PUNCT
biomedich-761	32	42	gras	gras	PROPN
biomedich-761	32	43	status	status	NOUN
biomedich-761	32	44	,	,	PUNCT
biomedich-761	32	45	and	and	CCONJ
biomedich-761	32	46	physicochemical	physicochemical	ADJ
biomedich-761	32	47	compatibility	compatibility	NOUN
biomedich-761	32	48	(	(	PUNCT
biomedich-761	32	49	garbiec	garbiec	NOUN
biomedich-761	32	50	et	et	PROPN
biomedich-761	32	51	al	al	PROPN
biomedich-761	32	52	.	.	PROPN
biomedich-761	32	53	,	,	PUNCT
biomedich-761	32	54	2023	2023	NUM
biomedich-761	32	55	;	;	PUNCT
biomedich-761	32	56	turek	turek	PROPN
biomedich-761	32	57	et	et	NOUN
biomedich-761	32	58	al	al	PROPN
biomedich-761	32	59	.	.	PROPN
biomedich-761	32	60	,	,	PUNCT
biomedich-761	32	61	2021	2021	NUM
biomedich-761	32	62	)	)	PUNCT
biomedich-761	32	63	.	.	PUNCT
biomedich-761	33	1	ina	ina	PROPN
biomedich-761	33	2	has	have	AUX
biomedich-761	33	3	been	be	AUX
biomedich-761	33	4	reported	report	VERB
biomedich-761	33	5	to	to	PART
biomedich-761	33	6	enhance	enhance	VERB
biomedich-761	33	7	solubility	solubility	NOUN
biomedich-761	33	8	and	and	CCONJ
biomedich-761	33	9	inhibit	inhibit	VERB
biomedich-761	33	10	recrystallization	recrystallization	NOUN
biomedich-761	33	11	in	in	ADP
biomedich-761	33	12	co	co	ADJ
biomedich-761	33	13	-	-	ADJ
biomedich-761	33	14	amorphous	amorphous	ADJ
biomedich-761	33	15	systems	system	NOUN
biomedich-761	33	16	and	and	CCONJ
biomedich-761	33	17	cocrystals	cocrystal	NOUN
biomedich-761	33	18	by	by	ADP
biomedich-761	33	19	stabilizing	stabilize	VERB
biomedich-761	33	20	the	the	DET
biomedich-761	33	21	high	high	ADJ
biomedich-761	33	22	-	-	PUNCT
biomedich-761	33	23	energy	energy	NOUN
biomedich-761	33	24	non	non	ADJ
biomedich-761	33	25	-	-	ADJ
biomedich-761	33	26	crystalline	crystalline	ADJ
biomedich-761	33	27	phase	phase	NOUN
biomedich-761	33	28	of	of	ADP
biomedich-761	33	29	the	the	DET
biomedich-761	33	30	drug	drug	NOUN
biomedich-761	33	31	(	(	PUNCT
biomedich-761	33	32	suknuntha	suknuntha	NOUN
biomedich-761	33	33	et	et	PROPN
biomedich-761	33	34	al	al	PROPN
biomedich-761	33	35	.	.	PROPN
biomedich-761	33	36	,	,	PUNCT
biomedich-761	33	37	2023	2023	NUM
biomedich-761	33	38	)	)	PUNCT
biomedich-761	33	39	.	.	PUNCT
biomedich-761	34	1	although	although	SCONJ
biomedich-761	34	2	several	several	ADJ
biomedich-761	34	3	studies	study	NOUN
biomedich-761	34	4	have	have	AUX
biomedich-761	34	5	demonstrated	demonstrate	VERB
biomedich-761	34	6	the	the	DET
biomedich-761	34	7	potential	potential	NOUN
biomedich-761	34	8	of	of	ADP
biomedich-761	34	9	ina	ina	PROPN
biomedich-761	34	10	in	in	ADP
biomedich-761	34	11	enhancing	enhance	VERB
biomedich-761	34	12	the	the	DET
biomedich-761	34	13	solubility	solubility	NOUN
biomedich-761	34	14	of	of	ADP
biomedich-761	34	15	other	other	ADJ
biomedich-761	34	16	bcs	bcs	NOUN
biomedich-761	34	17	class	class	NOUN
biomedich-761	34	18	ii	ii	NOUN
biomedich-761	34	19	drugs	drug	NOUN
biomedich-761	34	20	,	,	PUNCT
biomedich-761	34	21	limited	limited	ADJ
biomedich-761	34	22	research	research	NOUN
biomedich-761	34	23	has	have	AUX
biomedich-761	34	24	specifically	specifically	ADV
biomedich-761	34	25	investigated	investigate	VERB
biomedich-761	34	26	its	its	PRON
biomedich-761	34	27	use	use	NOUN
biomedich-761	34	28	in	in	ADP
biomedich-761	34	29	forming	form	VERB
biomedich-761	34	30	crystalline	crystalline	ADJ
biomedich-761	34	31	solid	solid	ADJ
biomedich-761	34	32	dispersions	dispersion	NOUN
biomedich-761	34	33	with	with	ADP
biomedich-761	34	34	mefenamic	mefenamic	ADJ
biomedich-761	34	35	acid	acid	NOUN
biomedich-761	34	36	—	—	PUNCT
biomedich-761	34	37	particularly	particularly	ADV
biomedich-761	34	38	when	when	SCONJ
biomedich-761	34	39	no	no	DET
biomedich-761	34	40	new	new	ADJ
biomedich-761	34	41	crystalline	crystalline	NOUN
biomedich-761	34	42	phase	phase	NOUN
biomedich-761	34	43	is	be	AUX
biomedich-761	34	44	detectable	detectable	ADJ
biomedich-761	34	45	via	via	ADP
biomedich-761	34	46	pxrd	pxrd	NOUN
biomedich-761	34	47	.	.	PUNCT
biomedich-761	35	1	this	this	PRON
biomedich-761	35	2	presents	present	VERB
biomedich-761	35	3	a	a	DET
biomedich-761	35	4	unique	unique	ADJ
biomedich-761	35	5	opportunity	opportunity	NOUN
biomedich-761	35	6	to	to	PART
biomedich-761	35	7	explore	explore	VERB
biomedich-761	35	8	whether	whether	SCONJ
biomedich-761	35	9	dissolution	dissolution	ADJ
biomedich-761	35	10	enhancement	enhancement	NOUN
biomedich-761	35	11	can	can	AUX
biomedich-761	35	12	still	still	ADV
biomedich-761	35	13	occur	occur	VERB
biomedich-761	35	14	through	through	ADP
biomedich-761	35	15	molecular	molecular	ADJ
biomedich-761	35	16	-	-	PUNCT
biomedich-761	35	17	level	level	NOUN
biomedich-761	35	18	interactions	interaction	NOUN
biomedich-761	35	19	without	without	ADP
biomedich-761	35	20	visible	visible	ADJ
biomedich-761	35	21	amorphization	amorphization	NOUN
biomedich-761	35	22	or	or	CCONJ
biomedich-761	35	23	co	co	NOUN
biomedich-761	35	24	-	-	NOUN
biomedich-761	35	25	crystal	crystal	ADJ
biomedich-761	35	26	formation	formation	NOUN
biomedich-761	35	27	.	.	PUNCT
biomedich-761	36	1	this	this	DET
biomedich-761	36	2	study	study	NOUN
biomedich-761	36	3	aims	aim	VERB
biomedich-761	36	4	to	to	PART
biomedich-761	36	5	investigate	investigate	VERB
biomedich-761	36	6	the	the	DET
biomedich-761	36	7	physicochemical	physicochemical	ADJ
biomedich-761	36	8	characteristics	characteristic	NOUN
biomedich-761	36	9	and	and	CCONJ
biomedich-761	36	10	dissolution	dissolution	NOUN
biomedich-761	36	11	behavior	behavior	NOUN
biomedich-761	36	12	of	of	ADP
biomedich-761	36	13	mefenamic	mefenamic	ADJ
biomedich-761	36	14	acid	acid	NOUN
biomedich-761	36	15	–	–	PUNCT
biomedich-761	36	16	isonicotinamide	isonicotinamide	NOUN
biomedich-761	36	17	crystalline	crystalline	NOUN
biomedich-761	36	18	solid	solid	ADJ
biomedich-761	36	19	dispersions	dispersion	NOUN
biomedich-761	36	20	prepared	prepare	VERB
biomedich-761	36	21	via	via	ADP
biomedich-761	36	22	solvent	solvent	ADJ
biomedich-761	36	23	evaporation	evaporation	NOUN
biomedich-761	36	24	.	.	PUNCT
biomedich-761	37	1	through	through	ADP
biomedich-761	37	2	pxrd	pxrd	PROPN
biomedich-761	37	3	,	,	PUNCT
biomedich-761	37	4	dsc	dsc	PROPN
biomedich-761	37	5	,	,	PUNCT
biomedich-761	37	6	ftir	ftir	PROPN
biomedich-761	37	7	,	,	PUNCT
biomedich-761	37	8	and	and	CCONJ
biomedich-761	37	9	dissolution	dissolution	ADJ
biomedich-761	37	10	analysis	analysis	NOUN
biomedich-761	37	11	,	,	PUNCT
biomedich-761	37	12	this	this	DET
biomedich-761	37	13	research	research	NOUN
biomedich-761	37	14	explores	explore	VERB
biomedich-761	37	15	whether	whether	SCONJ
biomedich-761	37	16	such	such	ADJ
biomedich-761	37	17	systems	system	NOUN
biomedich-761	37	18	can	can	AUX
biomedich-761	37	19	effectively	effectively	ADV
biomedich-761	37	20	improve	improve	VERB
biomedich-761	37	21	solubility	solubility	NOUN
biomedich-761	37	22	,	,	PUNCT
biomedich-761	37	23	offering	offer	VERB
biomedich-761	37	24	a	a	DET
biomedich-761	37	25	novel	novel	ADJ
biomedich-761	37	26	strategy	strategy	NOUN
biomedich-761	37	27	for	for	ADP
biomedich-761	37	28	formulating	formulate	VERB
biomedich-761	37	29	poorly	poorly	ADV
biomedich-761	37	30	watersoluble	watersoluble	ADJ
biomedich-761	37	31	nsaids	nsaid	NOUN
biomedich-761	37	32	.	.	PUNCT
biomedich-761	38	1	materials	material	NOUN
biomedich-761	38	2	and	and	CCONJ
biomedich-761	38	3	methods	method	NOUN
biomedich-761	38	4	materials	material	NOUN
biomedich-761	38	5	mefenamic	mefenamic	NOUN
biomedich-761	38	6	acid	acid	NOUN
biomedich-761	38	7	(	(	PUNCT
biomedich-761	38	8	mefa	mefa	PROPN
biomedich-761	38	9	)	)	PUNCT
biomedich-761	38	10	was	be	AUX
biomedich-761	38	11	obtained	obtain	VERB
biomedich-761	38	12	from	from	ADP
biomedich-761	38	13	pt	pt	PROPN
biomedich-761	38	14	.	.	PROPN
biomedich-761	38	15	kimia	kimia	PROPN
biomedich-761	38	16	farma	farma	PROPN
biomedich-761	38	17	tbk	tbk	PROPN
biomedich-761	38	18	(	(	PUNCT
biomedich-761	38	19	indonesia	indonesia	PROPN
biomedich-761	38	20	)	)	PUNCT
biomedich-761	38	21	as	as	ADP
biomedich-761	38	22	the	the	DET
biomedich-761	38	23	active	active	ADJ
biomedich-761	38	24	pharmaceutical	pharmaceutical	ADJ
biomedich-761	38	25	ingredient	ingredient	NOUN
biomedich-761	38	26	(	(	PUNCT
biomedich-761	38	27	api	api	NOUN
biomedich-761	38	28	)	)	PUNCT
biomedich-761	38	29	.	.	PUNCT
biomedich-761	39	1	isonicotinamide	isonicotinamide	ADV
biomedich-761	39	2	(	(	PUNCT
biomedich-761	39	3	ina	ina	PROPN
biomedich-761	39	4	)	)	PUNCT
biomedich-761	39	5	,	,	PUNCT
biomedich-761	39	6	used	use	VERB
biomedich-761	39	7	as	as	ADP
biomedich-761	39	8	a	a	DET
biomedich-761	39	9	lowmolecular	lowmolecular	ADJ
biomedich-761	39	10	-	-	PUNCT
biomedich-761	39	11	weight	weight	NOUN
biomedich-761	39	12	co	co	NOUN
biomedich-761	39	13	-	-	NOUN
biomedich-761	39	14	former	former	ADJ
biomedich-761	39	15	,	,	PUNCT
biomedich-761	39	16	was	be	AUX
biomedich-761	39	17	procured	procure	VERB
biomedich-761	39	18	from	from	ADP
biomedich-761	39	19	merck	merck	PROPN
biomedich-761	39	20	(	(	PUNCT
biomedich-761	39	21	germany	germany	PROPN
biomedich-761	39	22	)	)	PUNCT
biomedich-761	39	23	.	.	PUNCT
biomedich-761	40	1	all	all	DET
biomedich-761	40	2	other	other	ADJ
biomedich-761	40	3	solvents	solvent	NOUN
biomedich-761	40	4	and	and	CCONJ
biomedich-761	40	5	reagents	reagent	NOUN
biomedich-761	40	6	were	be	AUX
biomedich-761	40	7	of	of	ADP
biomedich-761	40	8	analytical	analytical	ADJ
biomedich-761	40	9	grade	grade	NOUN
biomedich-761	40	10	and	and	CCONJ
biomedich-761	40	11	used	use	VERB
biomedich-761	40	12	without	without	ADP
biomedich-761	40	13	further	further	ADJ
biomedich-761	40	14	purification	purification	NOUN
biomedich-761	40	15	.	.	PUNCT
biomedich-761	41	1	distilled	distil	VERB
biomedich-761	41	2	water	water	NOUN
biomedich-761	41	3	was	be	AUX
biomedich-761	41	4	used	use	VERB
biomedich-761	41	5	throughout	throughout	ADP
biomedich-761	41	6	the	the	DET
biomedich-761	41	7	experiments	experiment	NOUN
biomedich-761	41	8	for	for	ADP
biomedich-761	41	9	solubility	solubility	NOUN
biomedich-761	41	10	and	and	CCONJ
biomedich-761	41	11	dissolution	dissolution	NOUN
biomedich-761	41	12	studies	study	NOUN
biomedich-761	41	13	.	.	PUNCT
biomedich-761	42	1	instruments	instrument	VERB
biomedich-761	42	2	the	the	DET
biomedich-761	42	3	solid	solid	ADJ
biomedich-761	42	4	-	-	PUNCT
biomedich-761	42	5	state	state	NOUN
biomedich-761	42	6	characterization	characterization	NOUN
biomedich-761	42	7	of	of	ADP
biomedich-761	42	8	the	the	DET
biomedich-761	42	9	samples	sample	NOUN
biomedich-761	42	10	was	be	AUX
biomedich-761	42	11	conducted	conduct	VERB
biomedich-761	42	12	using	use	VERB
biomedich-761	42	13	several	several	ADJ
biomedich-761	42	14	instruments	instrument	NOUN
biomedich-761	42	15	.	.	PUNCT
biomedich-761	43	1	differential	differential	ADJ
biomedich-761	43	2	scanning	scan	VERB
biomedich-761	43	3	calorimetry	calorimetry	NOUN
biomedich-761	43	4	(	(	PUNCT
biomedich-761	43	5	dsc	dsc	NOUN
biomedich-761	43	6	)	)	PUNCT
biomedich-761	43	7	analysis	analysis	NOUN
biomedich-761	43	8	was	be	AUX
biomedich-761	43	9	performed	perform	VERB
biomedich-761	43	10	with	with	ADP
biomedich-761	43	11	a	a	DET
biomedich-761	43	12	shimadzu	shimadzu	NOUN
biomedich-761	43	13	dsc-60	dsc-60	ADV
biomedich-761	43	14	plus	plus	CCONJ
biomedich-761	43	15	(	(	PUNCT
biomedich-761	43	16	japan	japan	PROPN
biomedich-761	43	17	)	)	PUNCT
biomedich-761	43	18	,	,	PUNCT
biomedich-761	43	19	calibrated	calibrate	VERB
biomedich-761	43	20	using	use	VERB
biomedich-761	43	21	the	the	DET
biomedich-761	43	22	indium	indium	NOUN
biomedich-761	43	23	standard	standard	NOUN
biomedich-761	43	24	,	,	PUNCT
biomedich-761	43	25	operating	operate	VERB
biomedich-761	43	26	in	in	ADP
biomedich-761	43	27	a	a	DET
biomedich-761	43	28	nitrogen	nitrogen	NOUN
biomedich-761	43	29	atmosphere	atmosphere	NOUN
biomedich-761	43	30	.	.	PUNCT
biomedich-761	44	1	powder	powder	NOUN
biomedich-761	44	2	x	x	PROPN
biomedich-761	44	3	-	-	NOUN
biomedich-761	44	4	ray	ray	NOUN
biomedich-761	44	5	diffraction	diffraction	NOUN
biomedich-761	44	6	(	(	PUNCT
biomedich-761	44	7	pxrd	pxrd	PROPN
biomedich-761	44	8	)	)	PUNCT
biomedich-761	44	9	was	be	AUX
biomedich-761	44	10	carried	carry	VERB
biomedich-761	44	11	out	out	ADP
biomedich-761	44	12	using	use	VERB
biomedich-761	44	13	a	a	DET
biomedich-761	44	14	panalytical	panalytical	ADJ
biomedich-761	44	15	x’pert	x’pert	PROPN
biomedich-761	44	16	pro	pro	ADJ
biomedich-761	44	17	diffractometer	diffractometer	NOUN
biomedich-761	44	18	(	(	PUNCT
biomedich-761	44	19	netherlands	netherlands	PROPN
biomedich-761	44	20	)	)	PUNCT
biomedich-761	44	21	with	with	ADP
biomedich-761	44	22	cu	cu	PROPN
biomedich-761	44	23	kα	kα	PROPN
biomedich-761	44	24	radiation	radiation	NOUN
biomedich-761	44	25	(	(	PUNCT
biomedich-761	44	26	λ	λ	X
biomedich-761	44	27	=	=	SYM
biomedich-761	44	28	1.5406	1.5406	NUM
biomedich-761	44	29	å	å	NOUN
biomedich-761	44	30	)	)	PUNCT
biomedich-761	44	31	,	,	PUNCT
biomedich-761	44	32	operating	operate	VERB
biomedich-761	44	33	at	at	ADP
biomedich-761	44	34	40	40	NUM
biomedich-761	44	35	kv	kv	PROPN
biomedich-761	44	36	and	and	CCONJ
biomedich-761	44	37	30	30	NUM
biomedich-761	44	38	ma	ma	PROPN
biomedich-761	44	39	.	.	PROPN
biomedich-761	45	1	scanning	scanning	NOUN
biomedich-761	45	2	was	be	AUX
biomedich-761	45	3	performed	perform	VERB
biomedich-761	45	4	over	over	ADP
biomedich-761	45	5	a	a	DET
biomedich-761	45	6	2θ	2θ	NUM
biomedich-761	45	7	range	range	NOUN
biomedich-761	45	8	of	of	ADP
biomedich-761	45	9	5–40	5–40	PROPN
biomedich-761	45	10	°	°	PROPN
biomedich-761	45	11	.	.	PUNCT
biomedich-761	46	1	fourier	fourier	NOUN
biomedich-761	46	2	-	-	PUNCT
biomedich-761	46	3	transform	transform	NOUN
biomedich-761	46	4	infrared	infrared	NOUN
biomedich-761	46	5	(	(	PUNCT
biomedich-761	46	6	ftir	ftir	NOUN
biomedich-761	46	7	)	)	PUNCT
biomedich-761	46	8	spectroscopy	spectroscopy	NOUN
biomedich-761	46	9	was	be	AUX
biomedich-761	46	10	performed	perform	VERB
biomedich-761	46	11	using	use	VERB
biomedich-761	46	12	a	a	DET
biomedich-761	46	13	bruker	bruker	PROPN
biomedich-761	46	14	alpha	alpha	PROPN
biomedich-761	46	15	ii	ii	PROPN
biomedich-761	46	16	ftir	ftir	PROPN
biomedich-761	46	17	spectrometer	spectrometer	PROPN
biomedich-761	46	18	(	(	PUNCT
biomedich-761	46	19	germany	germany	PROPN
biomedich-761	46	20	)	)	PUNCT
biomedich-761	46	21	in	in	ADP
biomedich-761	46	22	the	the	DET
biomedich-761	46	23	4000–500	4000–500	NOUN
biomedich-761	46	24	cm⁻¹	cm⁻¹	NOUN
biomedich-761	46	25	range	range	NOUN
biomedich-761	46	26	using	use	VERB
biomedich-761	46	27	the	the	DET
biomedich-761	46	28	kbr	kbr	PROPN
biomedich-761	46	29	pellet	pellet	NOUN
biomedich-761	46	30	method	method	NOUN
biomedich-761	46	31	.	.	PUNCT
biomedich-761	47	1	dissolution	dissolution	PROPN
biomedich-761	47	2	testing	testing	NOUN
biomedich-761	47	3	was	be	AUX
biomedich-761	47	4	conducted	conduct	VERB
biomedich-761	47	5	using	use	VERB
biomedich-761	47	6	a	a	DET
biomedich-761	47	7	usp	usp	NOUN
biomedich-761	47	8	type	type	NOUN
biomedich-761	47	9	ii	ii	PROPN
biomedich-761	47	10	paddle	paddle	NOUN
biomedich-761	47	11	apparatus	apparatus	NOUN
biomedich-761	47	12	(	(	PUNCT
biomedich-761	47	13	logan	logan	PROPN
biomedich-761	47	14	instruments	instruments	PROPN
biomedich-761	47	15	corp	corp	PROPN
biomedich-761	47	16	.	.	PROPN
biomedich-761	47	17	,	,	PUNCT
biomedich-761	47	18	usa	usa	PROPN
biomedich-761	47	19	)	)	PUNCT
biomedich-761	47	20	at	at	ADP
biomedich-761	47	21	75	75	NUM
biomedich-761	47	22	rpm	rpm	NOUN
biomedich-761	47	23	.	.	PUNCT
biomedich-761	48	1	uv	uv	NOUN
biomedich-761	48	2	-	-	PUNCT
biomedich-761	48	3	visible	visible	ADJ
biomedich-761	48	4	spectrophotometry	spectrophotometry	NOUN
biomedich-761	48	5	was	be	AUX
biomedich-761	48	6	conducted	conduct	VERB
biomedich-761	48	7	on	on	ADP
biomedich-761	48	8	a	a	DET
biomedich-761	48	9	shimadzu	shimadzu	ADJ
biomedich-761	48	10	uv1800	uv1800	PROPN
biomedich-761	48	11	(	(	PUNCT
biomedich-761	48	12	japan	japan	PROPN
biomedich-761	48	13	)	)	PUNCT
biomedich-761	48	14	for	for	ADP
biomedich-761	48	15	drug	drug	NOUN
biomedich-761	48	16	quantification	quantification	NOUN
biomedich-761	48	17	at	at	ADP
biomedich-761	48	18	285	285	NUM
biomedich-761	48	19	nm	nm	NOUN
biomedich-761	48	20	.	.	PUNCT
biomedich-761	49	1	preparation	preparation	NOUN
biomedich-761	49	2	of	of	ADP
biomedich-761	49	3	crystalline	crystalline	NOUN
biomedich-761	49	4	solid	solid	ADJ
biomedich-761	49	5	dispersions	dispersion	NOUN
biomedich-761	49	6	csds	csds	NOUN
biomedich-761	49	7	of	of	ADP
biomedich-761	49	8	mefa	mefa	PROPN
biomedich-761	49	9	and	and	CCONJ
biomedich-761	49	10	ina	ina	PROPN
biomedich-761	49	11	were	be	AUX
biomedich-761	49	12	prepared	prepare	VERB
biomedich-761	49	13	using	use	VERB
biomedich-761	49	14	the	the	DET
biomedich-761	49	15	solvent	solvent	ADJ
biomedich-761	49	16	evaporation	evaporation	NOUN
biomedich-761	49	17	method	method	NOUN
biomedich-761	49	18	,	,	PUNCT
biomedich-761	49	19	which	which	PRON
biomedich-761	49	20	allows	allow	VERB
biomedich-761	49	21	for	for	ADP
biomedich-761	49	22	homogeneous	homogeneous	ADJ
biomedich-761	49	23	mixing	mixing	NOUN
biomedich-761	49	24	and	and	CCONJ
biomedich-761	49	25	distribution	distribution	NOUN
biomedich-761	49	26	of	of	ADP
biomedich-761	49	27	drug	drug	NOUN
biomedich-761	49	28	and	and	CCONJ
biomedich-761	49	29	coformer	coformer	NOUN
biomedich-761	49	30	molecules	molecule	NOUN
biomedich-761	49	31	(	(	PUNCT
biomedich-761	49	32	chauhan	chauhan	PROPN
biomedich-761	49	33	et	et	PROPN
biomedich-761	49	34	al	al	PROPN
biomedich-761	49	35	.	.	PROPN
biomedich-761	49	36	,	,	PUNCT
biomedich-761	49	37	2005	2005	NUM
biomedich-761	49	38	;	;	PUNCT
biomedich-761	49	39	xie	xie	PROPN
biomedich-761	49	40	et	et	PROPN
biomedich-761	49	41	al	al	PROPN
biomedich-761	49	42	.	.	PROPN
biomedich-761	49	43	,	,	PUNCT
biomedich-761	49	44	2009	2009	NUM
biomedich-761	49	45	)	)	PUNCT
biomedich-761	49	46	.	.	PUNCT
biomedich-761	50	1	the	the	DET
biomedich-761	50	2	drug	drug	NOUN
biomedich-761	50	3	and	and	CCONJ
biomedich-761	50	4	ina	ina	PROPN
biomedich-761	50	5	were	be	AUX
biomedich-761	50	6	accurately	accurately	ADV
biomedich-761	50	7	weighed	weigh	VERB
biomedich-761	50	8	in	in	ADP
biomedich-761	50	9	molar	molar	ADJ
biomedich-761	50	10	ratios	ratio	NOUN
biomedich-761	50	11	of	of	ADP
biomedich-761	50	12	1:1	1:1	NUM
biomedich-761	50	13	,	,	PUNCT
biomedich-761	50	14	1:2	1:2	NUM
biomedich-761	50	15	,	,	PUNCT
biomedich-761	50	16	and	and	CCONJ
biomedich-761	50	17	2:1	2:1	NUM
biomedich-761	50	18	,	,	PUNCT
biomedich-761	50	19	then	then	ADV
biomedich-761	50	20	dissolved	dissolve	VERB
biomedich-761	50	21	in	in	ADP
biomedich-761	50	22	a	a	DET
biomedich-761	50	23	minimal	minimal	ADJ
biomedich-761	50	24	amount	amount	NOUN
biomedich-761	50	25	of	of	ADP
biomedich-761	50	26	ethanol	ethanol	NOUN
biomedich-761	50	27	as	as	ADP
biomedich-761	50	28	the	the	DET
biomedich-761	50	29	common	common	ADJ
biomedich-761	50	30	solvent	solvent	NOUN
biomedich-761	50	31	.	.	PUNCT
biomedich-761	51	1	the	the	DET
biomedich-761	51	2	resulting	result	VERB
biomedich-761	51	3	solutions	solution	NOUN
biomedich-761	51	4	were	be	AUX
biomedich-761	51	5	stirred	stir	VERB
biomedich-761	51	6	magnetically	magnetically	ADV
biomedich-761	51	7	at	at	ADP
biomedich-761	51	8	room	room	NOUN
biomedich-761	51	9	temperature	temperature	NOUN
biomedich-761	51	10	for	for	ADP
biomedich-761	51	11	1	1	NUM
biomedich-761	51	12	hour	hour	NOUN
biomedich-761	51	13	to	to	PART
biomedich-761	51	14	ensure	ensure	VERB
biomedich-761	51	15	complete	complete	ADJ
biomedich-761	51	16	mixing	mixing	NOUN
biomedich-761	51	17	.	.	PUNCT
biomedich-761	52	1	the	the	DET
biomedich-761	52	2	solvent	solvent	NOUN
biomedich-761	52	3	was	be	AUX
biomedich-761	52	4	evaporated	evaporate	VERB
biomedich-761	52	5	under	under	ADP
biomedich-761	52	6	reduced	reduce	VERB
biomedich-761	52	7	pressure	pressure	NOUN
biomedich-761	52	8	using	use	VERB
biomedich-761	52	9	a	a	DET
biomedich-761	52	10	rotary	rotary	ADJ
biomedich-761	52	11	evaporator	evaporator	NOUN
biomedich-761	52	12	at	at	ADP
biomedich-761	52	13	40	40	NUM
biomedich-761	52	14	°	°	NOUN
biomedich-761	52	15	c	c	NOUN
biomedich-761	52	16	.	.	PUNCT
biomedich-761	53	1	the	the	DET
biomedich-761	53	2	dried	dry	VERB
biomedich-761	53	3	residues	residue	NOUN
biomedich-761	53	4	were	be	AUX
biomedich-761	53	5	further	far	ADV
biomedich-761	53	6	desiccated	desiccate	VERB
biomedich-761	53	7	and	and	CCONJ
biomedich-761	53	8	pulverized	pulverize	VERB
biomedich-761	53	9	into	into	ADP
biomedich-761	53	10	fine	fine	ADJ
biomedich-761	53	11	powder	powder	NOUN
biomedich-761	53	12	using	use	VERB
biomedich-761	53	13	a	a	DET
biomedich-761	53	14	mortar	mortar	NOUN
biomedich-761	53	15	and	and	CCONJ
biomedich-761	53	16	pestle	pestle	NOUN
biomedich-761	53	17	,	,	PUNCT
biomedich-761	53	18	then	then	ADV
biomedich-761	53	19	stored	store	VERB
biomedich-761	53	20	in	in	ADP
biomedich-761	53	21	airtight	airtight	NOUN
biomedich-761	53	22	containers	container	NOUN
biomedich-761	53	23	until	until	ADP
biomedich-761	53	24	further	further	ADJ
biomedich-761	53	25	analysis	analysis	NOUN
biomedich-761	53	26	.	.	PUNCT
biomedich-761	54	1	this	this	DET
biomedich-761	54	2	method	method	NOUN
biomedich-761	54	3	was	be	AUX
biomedich-761	54	4	selected	select	VERB
biomedich-761	54	5	due	due	ADP
biomedich-761	54	6	to	to	ADP
biomedich-761	54	7	its	its	PRON
biomedich-761	54	8	ability	ability	NOUN
biomedich-761	54	9	to	to	PART
biomedich-761	54	10	promote	promote	VERB
biomedich-761	54	11	molecular	molecular	ADJ
biomedich-761	54	12	-	-	PUNCT
biomedich-761	54	13	level	level	NOUN
biomedich-761	54	14	interactions	interaction	NOUN
biomedich-761	54	15	without	without	ADP
biomedich-761	54	16	thermal	thermal	ADJ
biomedich-761	54	17	degradation	degradation	NOUN
biomedich-761	54	18	,	,	PUNCT
biomedich-761	54	19	which	which	PRON
biomedich-761	54	20	is	be	AUX
biomedich-761	54	21	particularly	particularly	ADV
biomedich-761	54	22	suitable	suitable	ADJ
biomedich-761	54	23	for	for	ADP
biomedich-761	54	24	thermolabile	thermolabile	NOUN
biomedich-761	54	25	compounds	compound	NOUN
biomedich-761	54	26	.	.	PUNCT
biomedich-761	55	1	ftir	ftir	PROPN
biomedich-761	55	2	analysis	analysis	NOUN
biomedich-761	55	3	fourier	fourier	NOUN
biomedich-761	55	4	-	-	PUNCT
biomedich-761	55	5	transform	transform	NOUN
biomedich-761	55	6	infrared	infrared	ADJ
biomedich-761	55	7	spectroscopy	spectroscopy	NOUN
biomedich-761	55	8	(	(	PUNCT
biomedich-761	55	9	ftir	ftir	PROPN
biomedich-761	55	10	)	)	PUNCT
biomedich-761	55	11	evaluated	evaluate	VERB
biomedich-761	55	12	the	the	DET
biomedich-761	55	13	potential	potential	ADJ
biomedich-761	55	14	intermolecular	intermolecular	ADJ
biomedich-761	55	15	interactions	interaction	NOUN
biomedich-761	55	16	between	between	ADP
biomedich-761	55	17	mefa	mefa	PROPN
biomedich-761	55	18	and	and	CCONJ
biomedich-761	55	19	ina	ina	PROPN
biomedich-761	55	20	within	within	ADP
biomedich-761	55	21	the	the	DET
biomedich-761	55	22	solid	solid	ADJ
biomedich-761	55	23	dispersions	dispersion	NOUN
biomedich-761	55	24	.	.	PUNCT
biomedich-761	56	1	the	the	DET
biomedich-761	56	2	samples	sample	NOUN
biomedich-761	56	3	were	be	AUX
biomedich-761	56	4	mixed	mix	VERB
biomedich-761	56	5	with	with	ADP
biomedich-761	56	6	potassium	potassium	NOUN
biomedich-761	56	7	bromide	bromide	NOUN
biomedich-761	56	8	(	(	PUNCT
biomedich-761	56	9	kbr	kbr	PROPN
biomedich-761	56	10	)	)	PUNCT
biomedich-761	56	11	and	and	CCONJ
biomedich-761	56	12	compressed	compress	VERB
biomedich-761	56	13	into	into	ADP
biomedich-761	56	14	pellets	pellet	NOUN
biomedich-761	56	15	.	.	PUNCT
biomedich-761	57	1	the	the	DET
biomedich-761	57	2	ftir	ftir	PROPN
biomedich-761	57	3	spectra	spectra	PROPN
biomedich-761	57	4	were	be	AUX
biomedich-761	57	5	recorded	record	VERB
biomedich-761	57	6	in	in	ADP
biomedich-761	57	7	the	the	DET
biomedich-761	57	8	4000–400	4000–400	NOUN
biomedich-761	57	9	cm⁻¹	cm⁻¹	PROPN
biomedich-761	57	10	region	region	NOUN
biomedich-761	57	11	.	.	PUNCT
biomedich-761	58	1	shifts	shift	NOUN
biomedich-761	58	2	in	in	ADP
biomedich-761	58	3	characteristic	characteristic	ADJ
biomedich-761	58	4	peaks	peak	NOUN
biomedich-761	58	5	of	of	ADP
biomedich-761	58	6	functional	functional	ADJ
biomedich-761	58	7	groups	group	NOUN
biomedich-761	58	8	were	be	AUX
biomedich-761	58	9	interpreted	interpret	VERB
biomedich-761	58	10	to	to	PART
biomedich-761	58	11	detect	detect	VERB
biomedich-761	58	12	hydrogen	hydrogen	NOUN
biomedich-761	58	13	bonding	bonding	NOUN
biomedich-761	58	14	or	or	CCONJ
biomedich-761	58	15	other	other	ADJ
biomedich-761	58	16	non	non	ADJ
biomedich-761	58	17	-	-	ADJ
biomedich-761	58	18	covalent	covalent	ADJ
biomedich-761	58	19	interactions	interaction	NOUN
biomedich-761	58	20	,	,	PUNCT
biomedich-761	58	21	which	which	PRON
biomedich-761	58	22	may	may	AUX
biomedich-761	58	23	indicate	indicate	VERB
biomedich-761	58	24	successful	successful	ADJ
biomedich-761	58	25	dispersion	dispersion	NOUN
biomedich-761	58	26	or	or	CCONJ
biomedich-761	58	27	complex	complex	ADJ
biomedich-761	58	28	formation	formation	NOUN
biomedich-761	58	29	(	(	PUNCT
biomedich-761	58	30	liu	liu	PROPN
biomedich-761	58	31	et	et	PROPN
biomedich-761	58	32	al	al	PROPN
biomedich-761	58	33	.	.	PROPN
biomedich-761	58	34	,	,	PUNCT
biomedich-761	58	35	2015	2015	NUM
biomedich-761	58	36	;	;	PUNCT
biomedich-761	58	37	wicaksono	wicaksono	NOUN
biomedich-761	58	38	et	et	PROPN
biomedich-761	58	39	al	al	PROPN
biomedich-761	58	40	.	.	PROPN
biomedich-761	58	41	,	,	PUNCT
biomedich-761	58	42	2019	2019	NUM
biomedich-761	58	43	)	)	PUNCT
biomedich-761	58	44	.	.	PUNCT
biomedich-761	59	1	dsc	dsc	NOUN
biomedich-761	59	2	analysis	analysis	NOUN
biomedich-761	59	3	differential	differential	NOUN
biomedich-761	59	4	scanning	scan	VERB
biomedich-761	59	5	calorimetry	calorimetry	NOUN
biomedich-761	59	6	(	(	PUNCT
biomedich-761	59	7	dsc	dsc	NOUN
biomedich-761	59	8	)	)	PUNCT
biomedich-761	59	9	was	be	AUX
biomedich-761	59	10	employed	employ	VERB
biomedich-761	59	11	to	to	PART
biomedich-761	59	12	investigate	investigate	VERB
biomedich-761	59	13	the	the	DET
biomedich-761	59	14	prepared	prepared	ADJ
biomedich-761	59	15	solid	solid	ADJ
biomedich-761	59	16	dispersions	dispersion	NOUN
biomedich-761	59	17	’	'	PUNCT
biomedich-761	59	18	thermal	thermal	ADJ
biomedich-761	59	19	properties	property	NOUN
biomedich-761	59	20	and	and	CCONJ
biomedich-761	59	21	crystalline	crystalline	NOUN
biomedich-761	59	22	behavior	behavior	NOUN
biomedich-761	59	23	compared	compare	VERB
biomedich-761	59	24	to	to	ADP
biomedich-761	59	25	the	the	DET
biomedich-761	59	26	pure	pure	ADJ
biomedich-761	59	27	drug	drug	NOUN
biomedich-761	59	28	and	and	CCONJ
biomedich-761	59	29	co	co	NOUN
biomedich-761	59	30	-	-	ADJ
biomedich-761	59	31	former	former	ADJ
biomedich-761	59	32	.	.	PUNCT
biomedich-761	60	1	approximately	approximately	ADV
biomedich-761	60	2	2–5	2–5	PROPN
biomedich-761	60	3	mg	mg	INTJ
biomedich-761	60	4	of	of	ADP
biomedich-761	60	5	each	each	DET
biomedich-761	60	6	sample	sample	NOUN
biomedich-761	60	7	was	be	AUX
biomedich-761	60	8	weighed	weigh	VERB
biomedich-761	60	9	and	and	CCONJ
biomedich-761	60	10	placed	place	VERB
biomedich-761	60	11	in	in	ADP
biomedich-761	60	12	sealed	seal	VERB
biomedich-761	60	13	aluminum	aluminum	NOUN
biomedich-761	60	14	pans	pan	NOUN
biomedich-761	60	15	.	.	PUNCT
biomedich-761	61	1	samples	sample	NOUN
biomedich-761	61	2	were	be	AUX
biomedich-761	61	3	scanned	scan	VERB
biomedich-761	61	4	from	from	ADP
biomedich-761	61	5	30	30	NUM
biomedich-761	61	6	°	°	NOUN
biomedich-761	61	7	c	c	NOUN
biomedich-761	61	8	to	to	ADP
biomedich-761	61	9	250	250	NUM
biomedich-761	61	10	°	°	NOUN
biomedich-761	61	11	c	c	NOUN
biomedich-761	61	12	at	at	ADP
biomedich-761	61	13	a	a	DET
biomedich-761	61	14	heating	heating	NOUN
biomedich-761	61	15	rate	rate	NOUN
biomedich-761	61	16	of	of	ADP
biomedich-761	61	17	10	10	NUM
biomedich-761	61	18	°	°	NOUN
biomedich-761	61	19	c	c	NOUN
biomedich-761	61	20	/	/	SYM
biomedich-761	61	21	min	min	NOUN
biomedich-761	61	22	under	under	ADP
biomedich-761	61	23	a	a	DET
biomedich-761	61	24	nitrogen	nitrogen	NOUN
biomedich-761	61	25	atmosphere	atmosphere	NOUN
biomedich-761	61	26	(	(	PUNCT
biomedich-761	61	27	alatas	alata	NOUN
biomedich-761	61	28	et	et	PROPN
biomedich-761	61	29	al	al	PROPN
biomedich-761	61	30	.	.	PROPN
biomedich-761	61	31	,	,	PUNCT
biomedich-761	61	32	2021	2021	NUM
biomedich-761	61	33	;	;	PUNCT
biomedich-761	61	34	nandi	nandi	NOUN
biomedich-761	61	35	et	et	PROPN
biomedich-761	61	36	al	al	PROPN
biomedich-761	61	37	.	.	PROPN
biomedich-761	61	38	,	,	PUNCT
biomedich-761	61	39	2021	2021	NUM
biomedich-761	61	40	)	)	PUNCT
biomedich-761	61	41	.	.	PUNCT
biomedich-761	62	1	the	the	DET
biomedich-761	62	2	appearance	appearance	NOUN
biomedich-761	62	3	or	or	CCONJ
biomedich-761	62	4	disappearance	disappearance	NOUN
biomedich-761	62	5	of	of	ADP
biomedich-761	62	6	endothermic	endothermic	ADJ
biomedich-761	62	7	peaks	peak	NOUN
biomedich-761	62	8	was	be	AUX
biomedich-761	62	9	used	use	VERB
biomedich-761	62	10	to	to	PART
biomedich-761	62	11	assess	assess	VERB
biomedich-761	62	12	melting	melting	NOUN
biomedich-761	62	13	point	point	NOUN
biomedich-761	62	14	depression	depression	NOUN
biomedich-761	62	15	,	,	PUNCT
biomedich-761	62	16	crystalline	crystalline	NOUN
biomedich-761	62	17	transitions	transition	NOUN
biomedich-761	62	18	,	,	PUNCT
biomedich-761	62	19	and	and	CCONJ
biomedich-761	62	20	potential	potential	ADJ
biomedich-761	62	21	amorphization	amorphization	NOUN
biomedich-761	62	22	(	(	PUNCT
biomedich-761	62	23	wdowiak	wdowiak	PROPN
biomedich-761	62	24	et	et	PROPN
biomedich-761	62	25	al	al	PROPN
biomedich-761	62	26	.	.	PROPN
biomedich-761	62	27	,	,	PUNCT
biomedich-761	62	28	2024	2024	NUM
biomedich-761	62	29	)	)	PUNCT
biomedich-761	62	30	.	.	PUNCT
biomedich-761	63	1	indra	indra	PROPN
biomedich-761	63	2	et	et	PROPN
biomedich-761	63	3	al	al	PROPN
biomedich-761	63	4	.	.	PROPN
biomedich-761	63	5	–	–	PUNCT
biomedich-761	63	6	crystalline	crystalline	X
biomedich-761	63	7	solid	solid	ADJ
biomedich-761	63	8	dispersion	dispersion	NOUN
biomedich-761	63	9	for	for	ADP
biomedich-761	63	10	mefenamic	mefenamic	ADJ
biomedich-761	63	11	acid	acid	NOUN
biomedich-761	63	12	603	603	NUM
biomedich-761	63	13	dissolution	dissolution	NOUN
biomedich-761	63	14	testing	testing	NOUN
biomedich-761	63	15	the	the	DET
biomedich-761	63	16	dissolution	dissolution	NOUN
biomedich-761	63	17	rate	rate	NOUN
biomedich-761	63	18	of	of	ADP
biomedich-761	63	19	mefa	mefa	PROPN
biomedich-761	63	20	in	in	ADP
biomedich-761	63	21	solid	solid	ADJ
biomedich-761	63	22	dispersions	dispersion	NOUN
biomedich-761	63	23	and	and	CCONJ
biomedich-761	63	24	pure	pure	ADJ
biomedich-761	63	25	form	form	NOUN
biomedich-761	63	26	was	be	AUX
biomedich-761	63	27	assessed	assess	VERB
biomedich-761	63	28	using	use	VERB
biomedich-761	63	29	a	a	DET
biomedich-761	63	30	usp	usp	NOUN
biomedich-761	63	31	type	type	NOUN
biomedich-761	63	32	ii	ii	PROPN
biomedich-761	63	33	dissolution	dissolution	NOUN
biomedich-761	63	34	apparatus	apparatus	NOUN
biomedich-761	63	35	with	with	ADP
biomedich-761	63	36	900	900	NUM
biomedich-761	63	37	ml	ml	NOUN
biomedich-761	63	38	of	of	ADP
biomedich-761	63	39	phosphate	phosphate	ADJ
biomedich-761	63	40	buffer	buffer	NOUN
biomedich-761	63	41	(	(	PUNCT
biomedich-761	63	42	ph	ph	NOUN
biomedich-761	63	43	7.4	7.4	NUM
biomedich-761	63	44	)	)	PUNCT
biomedich-761	63	45	at	at	ADP
biomedich-761	63	46	37	37	NUM
biomedich-761	63	47	±	±	NUM
biomedich-761	63	48	0.5	0.5	NUM
biomedich-761	63	49	°	°	ADP
biomedich-761	63	50	c	c	NOUN
biomedich-761	63	51	and	and	CCONJ
biomedich-761	63	52	75	75	NUM
biomedich-761	63	53	rpm	rpm	NOUN
biomedich-761	63	54	.	.	PUNCT
biomedich-761	64	1	samples	sample	NOUN
biomedich-761	64	2	equivalent	equivalent	ADJ
biomedich-761	64	3	to	to	ADP
biomedich-761	64	4	50	50	NUM
biomedich-761	64	5	mg	mg	NOUN
biomedich-761	64	6	of	of	ADP
biomedich-761	64	7	mefa	mefa	PROPN
biomedich-761	64	8	were	be	AUX
biomedich-761	64	9	placed	place	VERB
biomedich-761	64	10	in	in	ADP
biomedich-761	64	11	the	the	DET
biomedich-761	64	12	dissolution	dissolution	NOUN
biomedich-761	64	13	vessel	vessel	NOUN
biomedich-761	64	14	.	.	PUNCT
biomedich-761	65	1	at	at	ADP
biomedich-761	65	2	predetermined	predetermine	VERB
biomedich-761	65	3	intervals	interval	NOUN
biomedich-761	65	4	(	(	PUNCT
biomedich-761	65	5	10	10	NUM
biomedich-761	65	6	,	,	PUNCT
biomedich-761	65	7	20	20	NUM
biomedich-761	65	8	,	,	PUNCT
biomedich-761	65	9	30	30	NUM
biomedich-761	65	10	,	,	PUNCT
biomedich-761	65	11	45	45	NUM
biomedich-761	65	12	,	,	PUNCT
biomedich-761	65	13	and	and	CCONJ
biomedich-761	65	14	60	60	NUM
biomedich-761	65	15	minutes	minute	NOUN
biomedich-761	65	16	)	)	PUNCT
biomedich-761	65	17	,	,	PUNCT
biomedich-761	65	18	5	5	NUM
biomedich-761	65	19	ml	ml	NOUN
biomedich-761	65	20	aliquots	aliquot	NOUN
biomedich-761	65	21	were	be	AUX
biomedich-761	65	22	withdrawn	withdraw	VERB
biomedich-761	65	23	and	and	CCONJ
biomedich-761	65	24	filtered	filter	VERB
biomedich-761	65	25	immediately	immediately	ADV
biomedich-761	65	26	.	.	PUNCT
biomedich-761	66	1	the	the	DET
biomedich-761	66	2	withdrawn	withdraw	VERB
biomedich-761	66	3	volume	volume	NOUN
biomedich-761	66	4	was	be	AUX
biomedich-761	66	5	replaced	replace	VERB
biomedich-761	66	6	with	with	ADP
biomedich-761	66	7	a	a	DET
biomedich-761	66	8	fresh	fresh	ADJ
biomedich-761	66	9	medium	medium	NOUN
biomedich-761	66	10	.	.	PUNCT
biomedich-761	67	1	drug	drug	NOUN
biomedich-761	67	2	content	content	NOUN
biomedich-761	67	3	was	be	AUX
biomedich-761	67	4	analyzed	analyze	VERB
biomedich-761	67	5	spectrophotometrically	spectrophotometrically	ADV
biomedich-761	67	6	at	at	ADP
biomedich-761	67	7	285	285	NUM
biomedich-761	67	8	nm	nm	NOUN
biomedich-761	67	9	.	.	PUNCT
biomedich-761	68	1	this	this	DET
biomedich-761	68	2	test	test	NOUN
biomedich-761	68	3	was	be	AUX
biomedich-761	68	4	critical	critical	ADJ
biomedich-761	68	5	for	for	ADP
biomedich-761	68	6	evaluating	evaluate	VERB
biomedich-761	68	7	the	the	DET
biomedich-761	68	8	dissolution	dissolution	NOUN
biomedich-761	68	9	enhancement	enhancement	NOUN
biomedich-761	68	10	resulting	result	VERB
biomedich-761	68	11	from	from	ADP
biomedich-761	68	12	solid	solid	ADJ
biomedich-761	68	13	dispersion	dispersion	NOUN
biomedich-761	68	14	formulation	formulation	NOUN
biomedich-761	68	15	(	(	PUNCT
biomedich-761	68	16	miller	miller	PROPN
biomedich-761	68	17	et	et	PROPN
biomedich-761	68	18	al	al	PROPN
biomedich-761	68	19	.	.	PROPN
biomedich-761	68	20	,	,	PUNCT
biomedich-761	68	21	2012	2012	NUM
biomedich-761	68	22	;	;	PUNCT
biomedich-761	68	23	park	park	NOUN
biomedich-761	68	24	et	et	PROPN
biomedich-761	68	25	al	al	PROPN
biomedich-761	68	26	.	.	PROPN
biomedich-761	68	27	,	,	PUNCT
biomedich-761	68	28	2018	2018	NUM
biomedich-761	68	29	)	)	PUNCT
biomedich-761	68	30	.	.	PUNCT
biomedich-761	69	1	results	result	NOUN
biomedich-761	69	2	and	and	CCONJ
biomedich-761	69	3	discussion	discussion	VERB
biomedich-761	69	4	the	the	DET
biomedich-761	69	5	physicochemical	physicochemical	ADJ
biomedich-761	69	6	characterization	characterization	NOUN
biomedich-761	69	7	of	of	ADP
biomedich-761	69	8	csds	csds	NOUN
biomedich-761	69	9	of	of	ADP
biomedich-761	69	10	mefa	mefa	PROPN
biomedich-761	69	11	with	with	ADP
biomedich-761	69	12	ina	ina	PROPN
biomedich-761	69	13	prepared	prepare	VERB
biomedich-761	69	14	via	via	ADP
biomedich-761	69	15	the	the	DET
biomedich-761	69	16	solvent	solvent	NOUN
biomedich-761	69	17	evaporation	evaporation	NOUN
biomedich-761	69	18	method	method	NOUN
biomedich-761	69	19	was	be	AUX
biomedich-761	69	20	conducted	conduct	VERB
biomedich-761	69	21	through	through	ADP
biomedich-761	69	22	dsc	dsc	PROPN
biomedich-761	69	23	,	,	PUNCT
biomedich-761	69	24	ftir	ftir	PROPN
biomedich-761	69	25	,	,	PUNCT
biomedich-761	69	26	pxrd	pxrd	NOUN
biomedich-761	69	27	,	,	PUNCT
biomedich-761	69	28	and	and	CCONJ
biomedich-761	69	29	dissolution	dissolution	PROPN
biomedich-761	69	30	testing	testing	NOUN
biomedich-761	69	31	.	.	PUNCT
biomedich-761	70	1	these	these	DET
biomedich-761	70	2	analytical	analytical	ADJ
biomedich-761	70	3	techniques	technique	NOUN
biomedich-761	70	4	provided	provide	VERB
biomedich-761	70	5	critical	critical	ADJ
biomedich-761	70	6	insights	insight	NOUN
biomedich-761	70	7	into	into	ADP
biomedich-761	70	8	the	the	DET
biomedich-761	70	9	solid	solid	ADJ
biomedich-761	70	10	-	-	PUNCT
biomedich-761	70	11	state	state	NOUN
biomedich-761	70	12	transformations	transformation	NOUN
biomedich-761	70	13	,	,	PUNCT
biomedich-761	70	14	interactions	interaction	NOUN
biomedich-761	70	15	,	,	PUNCT
biomedich-761	70	16	and	and	CCONJ
biomedich-761	70	17	biopharmaceutical	biopharmaceutical	ADJ
biomedich-761	70	18	behavior	behavior	NOUN
biomedich-761	70	19	of	of	ADP
biomedich-761	70	20	the	the	DET
biomedich-761	70	21	formulations	formulation	NOUN
biomedich-761	70	22	.	.	PUNCT
biomedich-761	71	1	thermal	thermal	ADJ
biomedich-761	71	2	behavior	behavior	NOUN
biomedich-761	71	3	(	(	PUNCT
biomedich-761	71	4	dsc	dsc	NOUN
biomedich-761	71	5	analysis	analysis	NOUN
biomedich-761	71	6	)	)	PUNCT
biomedich-761	71	7	differential	differential	NOUN
biomedich-761	71	8	scanning	scan	VERB
biomedich-761	71	9	calorimetry	calorimetry	NOUN
biomedich-761	71	10	(	(	PUNCT
biomedich-761	71	11	dsc	dsc	NOUN
biomedich-761	71	12	)	)	PUNCT
biomedich-761	71	13	was	be	AUX
biomedich-761	71	14	conducted	conduct	VERB
biomedich-761	71	15	to	to	PART
biomedich-761	71	16	investigate	investigate	VERB
biomedich-761	71	17	the	the	DET
biomedich-761	71	18	thermal	thermal	ADJ
biomedich-761	71	19	behavior	behavior	NOUN
biomedich-761	71	20	and	and	CCONJ
biomedich-761	71	21	physical	physical	ADJ
biomedich-761	71	22	state	state	NOUN
biomedich-761	71	23	of	of	ADP
biomedich-761	71	24	mefa	mefa	PROPN
biomedich-761	71	25	in	in	ADP
biomedich-761	71	26	crystalline	crystalline	NOUN
biomedich-761	71	27	solid	solid	ADJ
biomedich-761	71	28	dispersions	dispersion	NOUN
biomedich-761	71	29	formulated	formulate	VERB
biomedich-761	71	30	with	with	ADP
biomedich-761	71	31	varying	vary	VERB
biomedich-761	71	32	molar	molar	ADJ
biomedich-761	71	33	ratios	ratio	NOUN
biomedich-761	71	34	of	of	ADP
biomedich-761	71	35	the	the	DET
biomedich-761	71	36	small	small	ADJ
biomedich-761	71	37	-	-	PUNCT
biomedich-761	71	38	molecule	molecule	NOUN
biomedich-761	71	39	co	co	ADJ
biomedich-761	71	40	-	-	ADJ
biomedich-761	71	41	former	former	ADJ
biomedich-761	71	42	ina	ina	PROPN
biomedich-761	71	43	.	.	PUNCT
biomedich-761	72	1	as	as	SCONJ
biomedich-761	72	2	shown	show	VERB
biomedich-761	72	3	in	in	ADP
biomedich-761	72	4	figure	figure	NOUN
biomedich-761	72	5	1	1	NUM
biomedich-761	72	6	,	,	PUNCT
biomedich-761	72	7	pure	pure	ADJ
biomedich-761	72	8	mefa	mefa	PROPN
biomedich-761	72	9	(	(	PUNCT
biomedich-761	72	10	sample	sample	NOUN
biomedich-761	72	11	a	a	PRON
biomedich-761	72	12	)	)	PUNCT
biomedich-761	72	13	exhibited	exhibit	VERB
biomedich-761	72	14	a	a	DET
biomedich-761	72	15	sharp	sharp	ADJ
biomedich-761	72	16	endothermic	endothermic	ADJ
biomedich-761	72	17	peak	peak	NOUN
biomedich-761	72	18	at	at	ADP
biomedich-761	72	19	approximately	approximately	ADV
biomedich-761	72	20	230	230	NUM
biomedich-761	72	21	 	 	SPACE
biomedich-761	72	22	°	°	NOUN
biomedich-761	72	23	c	c	NOUN
biomedich-761	72	24	,	,	PUNCT
biomedich-761	72	25	corresponding	correspond	VERB
biomedich-761	72	26	to	to	ADP
biomedich-761	72	27	its	its	PRON
biomedich-761	72	28	melting	melting	NOUN
biomedich-761	72	29	point	point	NOUN
biomedich-761	72	30	and	and	CCONJ
biomedich-761	72	31	confirming	confirm	VERB
biomedich-761	72	32	its	its	PRON
biomedich-761	72	33	crystalline	crystalline	ADJ
biomedich-761	72	34	nature	nature	NOUN
biomedich-761	72	35	,	,	PUNCT
biomedich-761	72	36	consistent	consistent	ADJ
biomedich-761	72	37	with	with	ADP
biomedich-761	72	38	previously	previously	ADV
biomedich-761	72	39	reported	report	VERB
biomedich-761	72	40	data	datum	NOUN
biomedich-761	72	41	(	(	PUNCT
biomedich-761	72	42	nandi	nandi	NOUN
biomedich-761	72	43	et	et	PROPN
biomedich-761	72	44	al	al	PROPN
biomedich-761	72	45	.	.	PROPN
biomedich-761	72	46	,	,	PUNCT
biomedich-761	72	47	2021	2021	NUM
biomedich-761	72	48	)	)	PUNCT
biomedich-761	72	49	.	.	PUNCT
biomedich-761	73	1	in	in	ADP
biomedich-761	73	2	contrast	contrast	NOUN
biomedich-761	73	3	,	,	PUNCT
biomedich-761	73	4	solid	solid	ADJ
biomedich-761	73	5	dispersion	dispersion	NOUN
biomedich-761	73	6	samples	sample	NOUN
biomedich-761	73	7	(	(	PUNCT
biomedich-761	73	8	b	b	X
biomedich-761	73	9	–	–	PUNCT
biomedich-761	73	10	e	e	NOUN
biomedich-761	73	11	)	)	PUNCT
biomedich-761	73	12	demonstrated	demonstrate	VERB
biomedich-761	73	13	a	a	DET
biomedich-761	73	14	gradual	gradual	ADJ
biomedich-761	73	15	reduction	reduction	NOUN
biomedich-761	73	16	in	in	ADP
biomedich-761	73	17	the	the	DET
biomedich-761	73	18	intensity	intensity	NOUN
biomedich-761	73	19	and	and	CCONJ
biomedich-761	73	20	sharpness	sharpness	NOUN
biomedich-761	73	21	of	of	ADP
biomedich-761	73	22	this	this	DET
biomedich-761	73	23	melting	melting	NOUN
biomedich-761	73	24	endotherm	endotherm	NOUN
biomedich-761	73	25	,	,	PUNCT
biomedich-761	73	26	particularly	particularly	ADV
biomedich-761	73	27	in	in	ADP
biomedich-761	73	28	sample	sample	NOUN
biomedich-761	73	29	c	c	NOUN
biomedich-761	73	30	(	(	PUNCT
biomedich-761	73	31	1:2	1:2	NUM
biomedich-761	73	32	ratio	ratio	NOUN
biomedich-761	73	33	)	)	PUNCT
biomedich-761	73	34	,	,	PUNCT
biomedich-761	73	35	where	where	SCONJ
biomedich-761	73	36	the	the	DET
biomedich-761	73	37	peak	peak	NOUN
biomedich-761	73	38	nearly	nearly	ADV
biomedich-761	73	39	disappeared	disappear	VERB
biomedich-761	73	40	.	.	PUNCT
biomedich-761	74	1	figure	figure	VERB
biomedich-761	74	2	1	1	NUM
biomedich-761	74	3	.	.	PUNCT
biomedich-761	74	4	dsc	dsc	NOUN
biomedich-761	74	5	thermograms	thermogram	NOUN
biomedich-761	74	6	of	of	ADP
biomedich-761	74	7	mefa	mefa	PROPN
biomedich-761	74	8	(	(	PUNCT
biomedich-761	74	9	a	a	X
biomedich-761	74	10	)	)	PUNCT
biomedich-761	74	11	,	,	PUNCT
biomedich-761	74	12	ina	ina	PROPN
biomedich-761	74	13	(	(	PUNCT
biomedich-761	74	14	b	b	NOUN
biomedich-761	74	15	)	)	PUNCT
biomedich-761	74	16	,	,	PUNCT
biomedich-761	74	17	and	and	CCONJ
biomedich-761	74	18	csds	csds	NOUN
biomedich-761	74	19	with	with	ADP
biomedich-761	74	20	ratios	ratio	NOUN
biomedich-761	75	1	1:1	1:1	NUM
biomedich-761	75	2	(	(	PUNCT
biomedich-761	75	3	c	c	NOUN
biomedich-761	75	4	)	)	PUNCT
biomedich-761	75	5	,	,	PUNCT
biomedich-761	75	6	1:2	1:2	NUM
biomedich-761	75	7	(	(	PUNCT
biomedich-761	75	8	d	d	NOUN
biomedich-761	75	9	)	)	PUNCT
biomedich-761	75	10	,	,	PUNCT
biomedich-761	75	11	and	and	CCONJ
biomedich-761	75	12	2:1	2:1	NUM
biomedich-761	75	13	(	(	PUNCT
biomedich-761	75	14	e	e	NOUN
biomedich-761	75	15	)	)	PUNCT
biomedich-761	75	16	.	.	PUNCT
biomedich-761	76	1	the	the	DET
biomedich-761	76	2	diminished	diminish	VERB
biomedich-761	76	3	and	and	CCONJ
biomedich-761	76	4	broadened	broaden	VERB
biomedich-761	76	5	thermal	thermal	ADJ
biomedich-761	76	6	signals	signal	NOUN
biomedich-761	76	7	indicate	indicate	VERB
biomedich-761	76	8	a	a	DET
biomedich-761	76	9	significant	significant	ADJ
biomedich-761	76	10	reduction	reduction	NOUN
biomedich-761	76	11	in	in	ADP
biomedich-761	76	12	crystallinity	crystallinity	NOUN
biomedich-761	76	13	,	,	PUNCT
biomedich-761	76	14	suggestive	suggestive	ADJ
biomedich-761	76	15	of	of	ADP
biomedich-761	76	16	partial	partial	ADJ
biomedich-761	76	17	amorphization	amorphization	NOUN
biomedich-761	76	18	or	or	CCONJ
biomedich-761	76	19	molecular	molecular	ADJ
biomedich-761	76	20	-	-	PUNCT
biomedich-761	76	21	level	level	NOUN
biomedich-761	76	22	interaction	interaction	NOUN
biomedich-761	76	23	between	between	ADP
biomedich-761	76	24	mefa	mefa	PROPN
biomedich-761	76	25	and	and	CCONJ
biomedich-761	76	26	ina	ina	PROPN
biomedich-761	76	27	.	.	PUNCT
biomedich-761	77	1	notably	notably	ADV
biomedich-761	77	2	,	,	PUNCT
biomedich-761	77	3	samples	sample	NOUN
biomedich-761	77	4	d	d	NOUN
biomedich-761	77	5	and	and	CCONJ
biomedich-761	77	6	e	e	PROPN
biomedich-761	77	7	exhibited	exhibit	VERB
biomedich-761	77	8	a	a	DET
biomedich-761	77	9	single	single	ADJ
biomedich-761	77	10	broad	broad	ADJ
biomedich-761	77	11	glass	glass	NOUN
biomedich-761	77	12	transition	transition	NOUN
biomedich-761	77	13	temperature	temperature	NOUN
biomedich-761	77	14	(	(	PUNCT
biomedich-761	77	15	tg	tg	PROPN
biomedich-761	77	16	)	)	PUNCT
biomedich-761	77	17	,	,	PUNCT
biomedich-761	77	18	indicative	indicative	ADJ
biomedich-761	77	19	of	of	ADP
biomedich-761	77	20	a	a	DET
biomedich-761	77	21	homogenous	homogenous	ADJ
biomedich-761	77	22	molecular	molecular	ADJ
biomedich-761	77	23	dispersion	dispersion	NOUN
biomedich-761	77	24	and	and	CCONJ
biomedich-761	77	25	good	good	ADJ
biomedich-761	77	26	miscibility	miscibility	NOUN
biomedich-761	77	27	between	between	ADP
biomedich-761	77	28	the	the	DET
biomedich-761	77	29	drug	drug	NOUN
biomedich-761	77	30	and	and	CCONJ
biomedich-761	77	31	the	the	DET
biomedich-761	77	32	small	small	ADJ
biomedich-761	77	33	-	-	PUNCT
biomedich-761	77	34	molecule	molecule	NOUN
biomedich-761	77	35	co	co	NOUN
biomedich-761	77	36	-	-	NOUN
biomedich-761	77	37	former	former	ADJ
biomedich-761	77	38	.	.	PUNCT
biomedich-761	78	1	the	the	DET
biomedich-761	78	2	presence	presence	NOUN
biomedich-761	78	3	of	of	ADP
biomedich-761	78	4	a	a	DET
biomedich-761	78	5	single	single	ADJ
biomedich-761	78	6	tg	tg	NOUN
biomedich-761	78	7	—	—	PUNCT
biomedich-761	78	8	without	without	ADP
biomedich-761	78	9	any	any	DET
biomedich-761	78	10	distinct	distinct	ADJ
biomedich-761	78	11	melting	melting	NOUN
biomedich-761	78	12	peak	peak	NOUN
biomedich-761	78	13	—	—	PUNCT
biomedich-761	78	14	suggests	suggest	VERB
biomedich-761	78	15	the	the	DET
biomedich-761	78	16	formation	formation	NOUN
biomedich-761	78	17	of	of	ADP
biomedich-761	78	18	a	a	DET
biomedich-761	78	19	metastable	metastable	ADJ
biomedich-761	78	20	solid	solid	ADJ
biomedich-761	78	21	phase	phase	NOUN
biomedich-761	78	22	,	,	PUNCT
biomedich-761	78	23	potentially	potentially	ADV
biomedich-761	78	24	coamorphous	coamorphous	ADJ
biomedich-761	78	25	or	or	CCONJ
biomedich-761	78	26	weakly	weakly	ADJ
biomedich-761	78	27	crystalline	crystalline	NOUN
biomedich-761	78	28	,	,	PUNCT
biomedich-761	78	29	stabilized	stabilize	VERB
biomedich-761	78	30	through	through	ADP
biomedich-761	78	31	intermolecular	intermolecular	ADJ
biomedich-761	78	32	hydrogen	hydrogen	NOUN
biomedich-761	78	33	bonding	bonding	NOUN
biomedich-761	78	34	.	.	PUNCT
biomedich-761	79	1	this	this	DET
biomedich-761	79	2	behavior	behavior	NOUN
biomedich-761	79	3	underscores	underscore	VERB
biomedich-761	79	4	the	the	DET
biomedich-761	79	5	role	role	NOUN
biomedich-761	79	6	of	of	ADP
biomedich-761	79	7	the	the	DET
biomedich-761	79	8	co	co	NOUN
biomedich-761	79	9	-	-	ADJ
biomedich-761	79	10	former	former	ADJ
biomedich-761	79	11	ratio	ratio	NOUN
biomedich-761	79	12	in	in	ADP
biomedich-761	79	13	modifying	modify	VERB
biomedich-761	79	14	solid	solid	ADJ
biomedich-761	79	15	-	-	PUNCT
biomedich-761	79	16	state	state	NOUN
biomedich-761	79	17	properties	property	NOUN
biomedich-761	79	18	.	.	PUNCT
biomedich-761	80	1	as	as	SCONJ
biomedich-761	80	2	the	the	DET
biomedich-761	80	3	proportion	proportion	NOUN
biomedich-761	80	4	of	of	ADP
biomedich-761	80	5	ina	ina	PROPN
biomedich-761	80	6	increased	increase	VERB
biomedich-761	80	7	,	,	PUNCT
biomedich-761	80	8	the	the	DET
biomedich-761	80	9	system	system	NOUN
biomedich-761	80	10	transitioned	transition	VERB
biomedich-761	80	11	from	from	ADP
biomedich-761	80	12	a	a	DET
biomedich-761	80	13	crystalline	crystalline	NOUN
biomedich-761	80	14	to	to	ADP
biomedich-761	80	15	a	a	DET
biomedich-761	80	16	more	more	ADV
biomedich-761	80	17	amorphous	amorphous	ADJ
biomedich-761	80	18	or	or	CCONJ
biomedich-761	80	19	molecularly	molecularly	ADV
biomedich-761	80	20	integrated	integrate	VERB
biomedich-761	80	21	state	state	NOUN
biomedich-761	80	22	.	.	PUNCT
biomedich-761	81	1	these	these	DET
biomedich-761	81	2	findings	finding	NOUN
biomedich-761	81	3	are	be	AUX
biomedich-761	81	4	consistent	consistent	ADJ
biomedich-761	81	5	with	with	ADP
biomedich-761	81	6	previous	previous	ADJ
biomedich-761	81	7	reports	report	NOUN
biomedich-761	81	8	,	,	PUNCT
biomedich-761	81	9	such	such	ADJ
biomedich-761	81	10	as	as	ADP
biomedich-761	81	11	those	those	PRON
biomedich-761	81	12	by	by	ADP
biomedich-761	81	13	fitriani	fitriani	PROPN
biomedich-761	81	14	et	et	PROPN
biomedich-761	81	15	al	al	PROPN
biomedich-761	81	16	.	.	PROPN
biomedich-761	82	1	(	(	PUNCT
biomedich-761	82	2	2017	2017	NUM
biomedich-761	82	3	)	)	PUNCT
biomedich-761	82	4	,	,	PUNCT
biomedich-761	82	5	demonstrating	demonstrate	VERB
biomedich-761	82	6	that	that	PRON
biomedich-761	82	7	enhanced	enhance	VERB
biomedich-761	82	8	co	co	NOUN
biomedich-761	82	9	-	-	ADJ
biomedich-761	82	10	former	former	ADJ
biomedich-761	82	11	interaction	interaction	NOUN
biomedich-761	82	12	facilitates	facilitate	VERB
biomedich-761	82	13	the	the	DET
biomedich-761	82	14	disordering	disordering	NOUN
biomedich-761	82	15	of	of	ADP
biomedich-761	82	16	the	the	DET
biomedich-761	82	17	drug	drug	NOUN
biomedich-761	82	18	lattice	lattice	NOUN
biomedich-761	82	19	in	in	ADP
biomedich-761	82	20	nonpolymeric	nonpolymeric	ADJ
biomedich-761	82	21	matrices	matrix	NOUN
biomedich-761	82	22	.	.	PUNCT
biomedich-761	83	1	intermolecular	intermolecular	ADJ
biomedich-761	83	2	interactions	interaction	NOUN
biomedich-761	83	3	(	(	PUNCT
biomedich-761	83	4	ftir	ftir	NOUN
biomedich-761	83	5	analysis	analysis	NOUN
biomedich-761	83	6	)	)	PUNCT
biomedich-761	83	7	ftir	ftir	PROPN
biomedich-761	83	8	spectroscopy	spectroscopy	NOUN
biomedich-761	83	9	assessed	assess	VERB
biomedich-761	83	10	the	the	DET
biomedich-761	83	11	molecular	molecular	ADJ
biomedich-761	83	12	interactions	interaction	NOUN
biomedich-761	83	13	between	between	ADP
biomedich-761	83	14	mefa	mefa	PROPN
biomedich-761	83	15	and	and	CCONJ
biomedich-761	83	16	its	its	PRON
biomedich-761	83	17	co	co	NOUN
biomedich-761	83	18	-	-	NOUN
biomedich-761	83	19	formers	former	NOUN
biomedich-761	83	20	.	.	PUNCT
biomedich-761	84	1	the	the	DET
biomedich-761	84	2	spectra	spectra	PROPN
biomedich-761	84	3	in	in	ADP
biomedich-761	84	4	figure	figure	NOUN
biomedich-761	84	5	2	2	NUM
biomedich-761	84	6	show	show	VERB
biomedich-761	84	7	significant	significant	ADJ
biomedich-761	84	8	shifts	shift	NOUN
biomedich-761	84	9	and	and	CCONJ
biomedich-761	84	10	changes	change	NOUN
biomedich-761	84	11	in	in	ADP
biomedich-761	84	12	peak	peak	NOUN
biomedich-761	84	13	characteristics	characteristic	NOUN
biomedich-761	84	14	across	across	ADP
biomedich-761	84	15	different	different	ADJ
biomedich-761	84	16	formulations	formulation	NOUN
biomedich-761	84	17	.	.	PUNCT
biomedich-761	85	1	the	the	DET
biomedich-761	85	2	pure	pure	ADJ
biomedich-761	85	3	drug	drug	NOUN
biomedich-761	85	4	(	(	PUNCT
biomedich-761	85	5	a	a	PRON
biomedich-761	85	6	)	)	PUNCT
biomedich-761	85	7	exhibited	exhibit	VERB
biomedich-761	85	8	distinct	distinct	ADJ
biomedich-761	85	9	absorption	absorption	NOUN
biomedich-761	85	10	bands	band	NOUN
biomedich-761	85	11	corresponding	correspond	VERB
biomedich-761	85	12	to	to	ADP
biomedich-761	85	13	its	its	PRON
biomedich-761	85	14	functional	functional	ADJ
biomedich-761	85	15	groups	group	NOUN
biomedich-761	85	16	:	:	PUNCT
biomedich-761	85	17	the	the	DET
biomedich-761	85	18	n	n	CCONJ
biomedich-761	85	19	–	–	PUNCT
biomedich-761	85	20	h	h	NOUN
biomedich-761	85	21	stretching	stretch	VERB
biomedich-761	85	22	band	band	NOUN
biomedich-761	85	23	around	around	ADP
biomedich-761	85	24	3300	3300	NUM
biomedich-761	85	25	cm⁻¹	cm⁻¹	NOUN
biomedich-761	85	26	,	,	PUNCT
biomedich-761	85	27	c	c	PROPN
biomedich-761	85	28	=	=	X
biomedich-761	85	29	o	o	X
biomedich-761	85	30	stretching	stretch	VERB
biomedich-761	85	31	at	at	ADP
biomedich-761	85	32	~1650	~1650	ADP
biomedich-761	85	33	cm⁻¹	cm⁻¹	NOUN
biomedich-761	85	34	,	,	PUNCT
biomedich-761	85	35	and	and	CCONJ
biomedich-761	85	36	aromatic	aromatic	ADJ
biomedich-761	85	37	c	c	NOUN
biomedich-761	85	38	–	–	PUNCT
biomedich-761	85	39	h	h	NOUN
biomedich-761	85	40	bending	bending	NOUN
biomedich-761	85	41	near	near	ADP
biomedich-761	85	42	750	750	NUM
biomedich-761	85	43	cm⁻¹.	cm⁻¹.	NOUN
biomedich-761	85	44	upon	upon	SCONJ
biomedich-761	85	45	forming	form	VERB
biomedich-761	85	46	solid	solid	ADJ
biomedich-761	85	47	dispersions	dispersion	NOUN
biomedich-761	85	48	(	(	PUNCT
biomedich-761	85	49	samples	sample	NOUN
biomedich-761	85	50	b	b	NOUN
biomedich-761	85	51	through	through	ADP
biomedich-761	85	52	d	d	PROPN
biomedich-761	85	53	)	)	PUNCT
biomedich-761	85	54	,	,	PUNCT
biomedich-761	85	55	notable	notable	ADJ
biomedich-761	85	56	shifts	shift	NOUN
biomedich-761	85	57	and	and	CCONJ
biomedich-761	85	58	reductions	reduction	NOUN
biomedich-761	85	59	in	in	ADP
biomedich-761	85	60	the	the	DET
biomedich-761	85	61	intensity	intensity	NOUN
biomedich-761	85	62	of	of	ADP
biomedich-761	85	63	the	the	DET
biomedich-761	85	64	o	o	NOUN
biomedich-761	85	65	–	–	PUNCT
biomedich-761	85	66	h	h	NOUN
biomedich-761	85	67	and	and	CCONJ
biomedich-761	85	68	n	n	CCONJ
biomedich-761	85	69	–	–	PUNCT
biomedich-761	85	70	h	h	NOUN
biomedich-761	85	71	stretching	stretch	VERB
biomedich-761	85	72	vibrations	vibration	NOUN
biomedich-761	85	73	were	be	AUX
biomedich-761	85	74	observed	observe	VERB
biomedich-761	85	75	.	.	PUNCT
biomedich-761	86	1	in	in	ADP
biomedich-761	86	2	particular	particular	ADJ
biomedich-761	86	3	,	,	PUNCT
biomedich-761	86	4	the	the	DET
biomedich-761	86	5	broadening	broadening	NOUN
biomedich-761	86	6	and	and	CCONJ
biomedich-761	86	7	red	red	ADJ
biomedich-761	86	8	-	-	PUNCT
biomedich-761	86	9	shifting	shifting	NOUN
biomedich-761	86	10	of	of	ADP
biomedich-761	86	11	these	these	DET
biomedich-761	86	12	bands	band	NOUN
biomedich-761	86	13	suggest	suggest	VERB
biomedich-761	86	14	the	the	DET
biomedich-761	86	15	formation	formation	NOUN
biomedich-761	86	16	of	of	ADP
biomedich-761	86	17	intermolecular	intermolecular	ADJ
biomedich-761	86	18	hydrogen	hydrogen	NOUN
biomedich-761	86	19	bonds	bond	NOUN
biomedich-761	86	20	between	between	ADP
biomedich-761	86	21	the	the	DET
biomedich-761	86	22	carboxylic	carboxylic	ADJ
biomedich-761	86	23	or	or	CCONJ
biomedich-761	86	24	amine	amine	ADJ
biomedich-761	86	25	groups	group	NOUN
biomedich-761	86	26	of	of	ADP
biomedich-761	86	27	mefa	mefa	PROPN
biomedich-761	86	28	and	and	CCONJ
biomedich-761	86	29	the	the	DET
biomedich-761	86	30	functional	functional	ADJ
biomedich-761	86	31	groups	group	NOUN
biomedich-761	86	32	of	of	ADP
biomedich-761	86	33	the	the	DET
biomedich-761	86	34	co	co	NOUN
biomedich-761	86	35	-	-	NOUN
biomedich-761	86	36	former	former	ADJ
biomedich-761	86	37	(	(	PUNCT
biomedich-761	86	38	liu	liu	PROPN
biomedich-761	86	39	et	et	PROPN
biomedich-761	86	40	al	al	PROPN
biomedich-761	86	41	.	.	PROPN
biomedich-761	86	42	,	,	PUNCT
biomedich-761	86	43	2015	2015	NUM
biomedich-761	86	44	;	;	PUNCT
biomedich-761	86	45	oyama	oyama	PROPN
biomedich-761	86	46	et	et	PROPN
biomedich-761	86	47	al	al	PROPN
biomedich-761	86	48	.	.	PROPN
biomedich-761	86	49	,	,	PUNCT
biomedich-761	86	50	2024	2024	NUM
biomedich-761	86	51	)	)	PUNCT
biomedich-761	86	52	.	.	PUNCT
biomedich-761	87	1	such	such	ADJ
biomedich-761	87	2	interactions	interaction	NOUN
biomedich-761	87	3	imply	imply	VERB
biomedich-761	87	4	that	that	SCONJ
biomedich-761	87	5	the	the	DET
biomedich-761	87	6	drug	drug	NOUN
biomedich-761	87	7	has	have	AUX
biomedich-761	87	8	been	be	AUX
biomedich-761	87	9	effectively	effectively	ADV
biomedich-761	87	10	incorporated	incorporate	VERB
biomedich-761	87	11	into	into	ADP
biomedich-761	87	12	the	the	DET
biomedich-761	87	13	polymer	polymer	NOUN
biomedich-761	87	14	matrix	matrix	NOUN
biomedich-761	87	15	at	at	ADP
biomedich-761	87	16	a	a	DET
biomedich-761	87	17	molecular	molecular	ADJ
biomedich-761	87	18	level	level	NOUN
biomedich-761	87	19	.	.	PUNCT
biomedich-761	88	1	figure	figure	NOUN
biomedich-761	88	2	2	2	NUM
biomedich-761	88	3	.	.	PUNCT
biomedich-761	88	4	ftir	ftir	PROPN
biomedich-761	88	5	spectra	spectra	PROPN
biomedich-761	88	6	of	of	ADP
biomedich-761	88	7	mefa	mefa	PROPN
biomedich-761	88	8	(	(	PUNCT
biomedich-761	88	9	a	a	NOUN
biomedich-761	88	10	)	)	PUNCT
biomedich-761	88	11	,	,	PUNCT
biomedich-761	88	12	and	and	CCONJ
biomedich-761	88	13	their	their	PRON
biomedich-761	88	14	solid	solid	ADJ
biomedich-761	88	15	dispersions	dispersion	NOUN
biomedich-761	88	16	in	in	ADP
biomedich-761	88	17	ratios	ratio	NOUN
biomedich-761	88	18	1:1	1:1	NUM
biomedich-761	88	19	(	(	PUNCT
biomedich-761	88	20	b	b	NOUN
biomedich-761	88	21	)	)	PUNCT
biomedich-761	88	22	,	,	PUNCT
biomedich-761	88	23	1:2	1:2	NUM
biomedich-761	88	24	(	(	PUNCT
biomedich-761	88	25	c	c	NOUN
biomedich-761	88	26	)	)	PUNCT
biomedich-761	88	27	,	,	PUNCT
biomedich-761	88	28	and	and	CCONJ
biomedich-761	88	29	2:1	2:1	NUM
biomedich-761	88	30	(	(	PUNCT
biomedich-761	88	31	d	d	NOUN
biomedich-761	88	32	)	)	PUNCT
biomedich-761	88	33	.	.	PUNCT
biomedich-761	89	1	604	604	NUM
biomedich-761	89	2	biology	biology	NOUN
biomedich-761	89	3	,	,	PUNCT
biomedich-761	89	4	medicine	medicine	NOUN
biomedich-761	89	5	,	,	PUNCT
biomedich-761	89	6	&	&	CCONJ
biomedich-761	89	7	natural	natural	ADJ
biomedich-761	89	8	product	product	NOUN
biomedich-761	89	9	chemistry	chemistry	NOUN
biomedich-761	89	10	14	14	NUM
biomedich-761	89	11	(	(	PUNCT
biomedich-761	89	12	2	2	NUM
biomedich-761	89	13	)	)	PUNCT
biomedich-761	89	14	,	,	PUNCT
biomedich-761	89	15	2025	2025	NUM
biomedich-761	89	16	:	:	PUNCT
biomedich-761	89	17	601	601	NUM
biomedich-761	89	18	-	-	SYM
biomedich-761	89	19	607	607	NUM
biomedich-761	89	20	moreover	moreover	ADV
biomedich-761	89	21	,	,	PUNCT
biomedich-761	89	22	the	the	DET
biomedich-761	89	23	disappearance	disappearance	NOUN
biomedich-761	89	24	or	or	CCONJ
biomedich-761	89	25	weakening	weakening	NOUN
biomedich-761	89	26	of	of	ADP
biomedich-761	89	27	sharp	sharp	ADJ
biomedich-761	89	28	carbonyl	carbonyl	NOUN
biomedich-761	89	29	peaks	peak	NOUN
biomedich-761	89	30	in	in	ADP
biomedich-761	89	31	the	the	DET
biomedich-761	89	32	dispersion	dispersion	NOUN
biomedich-761	89	33	spectra	spectra	NOUN
biomedich-761	89	34	,	,	PUNCT
biomedich-761	89	35	particularly	particularly	ADV
biomedich-761	89	36	in	in	ADP
biomedich-761	89	37	sample	sample	NOUN
biomedich-761	89	38	c	c	NOUN
biomedich-761	89	39	,	,	PUNCT
biomedich-761	89	40	supports	support	VERB
biomedich-761	89	41	the	the	DET
biomedich-761	89	42	hypothesis	hypothesis	NOUN
biomedich-761	89	43	of	of	ADP
biomedich-761	89	44	drug	drug	NOUN
biomedich-761	89	45	–	–	PUNCT
biomedich-761	89	46	co	co	ADJ
biomedich-761	89	47	-	-	ADJ
biomedich-761	89	48	former	former	ADJ
biomedich-761	89	49	interaction	interaction	NOUN
biomedich-761	89	50	.	.	PUNCT
biomedich-761	90	1	this	this	PRON
biomedich-761	90	2	is	be	AUX
biomedich-761	90	3	further	far	ADV
biomedich-761	90	4	corroborated	corroborate	VERB
biomedich-761	90	5	by	by	ADP
biomedich-761	90	6	the	the	DET
biomedich-761	90	7	appearance	appearance	NOUN
biomedich-761	90	8	of	of	ADP
biomedich-761	90	9	new	new	ADJ
biomedich-761	90	10	absorption	absorption	NOUN
biomedich-761	90	11	bands	band	NOUN
biomedich-761	90	12	in	in	ADP
biomedich-761	90	13	the	the	DET
biomedich-761	90	14	fingerprint	fingerprint	NOUN
biomedich-761	90	15	region	region	NOUN
biomedich-761	90	16	(	(	PUNCT
biomedich-761	90	17	~1000–1500	~1000–1500	NOUN
biomedich-761	90	18	cm⁻¹	cm⁻¹	NOUN
biomedich-761	90	19	)	)	PUNCT
biomedich-761	90	20	,	,	PUNCT
biomedich-761	90	21	which	which	PRON
biomedich-761	90	22	are	be	AUX
biomedich-761	90	23	absent	absent	ADJ
biomedich-761	90	24	in	in	ADP
biomedich-761	90	25	the	the	DET
biomedich-761	90	26	spectra	spectra	NOUN
biomedich-761	90	27	of	of	ADP
biomedich-761	90	28	the	the	DET
biomedich-761	90	29	physical	physical	ADJ
biomedich-761	90	30	mixture	mixture	NOUN
biomedich-761	90	31	,	,	PUNCT
biomedich-761	90	32	indicating	indicate	VERB
biomedich-761	90	33	that	that	SCONJ
biomedich-761	90	34	molecular	molecular	ADJ
biomedich-761	90	35	-	-	PUNCT
biomedich-761	90	36	level	level	NOUN
biomedich-761	90	37	interactions	interaction	NOUN
biomedich-761	90	38	—	—	PUNCT
biomedich-761	90	39	likely	likely	ADJ
biomedich-761	90	40	hydrogen	hydrogen	NOUN
biomedich-761	90	41	bonding	bonding	NOUN
biomedich-761	90	42	—	—	PUNCT
biomedich-761	90	43	occurred	occur	VERB
biomedich-761	90	44	during	during	ADP
biomedich-761	90	45	the	the	DET
biomedich-761	90	46	preparation	preparation	NOUN
biomedich-761	90	47	of	of	ADP
biomedich-761	90	48	the	the	DET
biomedich-761	90	49	dispersions	dispersion	NOUN
biomedich-761	90	50	(	(	PUNCT
biomedich-761	90	51	guedes	guede	NOUN
biomedich-761	90	52	et	et	NOUN
biomedich-761	90	53	al	al	PROPN
biomedich-761	90	54	.	.	PROPN
biomedich-761	90	55	,	,	PUNCT
biomedich-761	90	56	2011	2011	NUM
biomedich-761	90	57	;	;	PUNCT
biomedich-761	90	58	qian	qian	PROPN
biomedich-761	90	59	et	et	PROPN
biomedich-761	90	60	al	al	PROPN
biomedich-761	90	61	.	.	PROPN
biomedich-761	90	62	,	,	PUNCT
biomedich-761	90	63	2015	2015	NUM
biomedich-761	90	64	)	)	PUNCT
biomedich-761	90	65	.	.	PUNCT
biomedich-761	91	1	crystalline	crystalline	PROPN
biomedich-761	91	2	behavior	behavior	NOUN
biomedich-761	91	3	(	(	PUNCT
biomedich-761	91	4	pxrd	pxrd	NOUN
biomedich-761	91	5	analysis	analysis	NOUN
biomedich-761	91	6	)	)	PUNCT
biomedich-761	91	7	pxrd	pxrd	NOUN
biomedich-761	91	8	analysis	analysis	NOUN
biomedich-761	91	9	,	,	PUNCT
biomedich-761	91	10	illustrated	illustrate	VERB
biomedich-761	91	11	in	in	ADP
biomedich-761	91	12	figure	figure	NOUN
biomedich-761	91	13	3	3	NUM
biomedich-761	91	14	,	,	PUNCT
biomedich-761	91	15	was	be	AUX
biomedich-761	91	16	utilized	utilize	VERB
biomedich-761	91	17	to	to	PART
biomedich-761	91	18	investigate	investigate	VERB
biomedich-761	91	19	the	the	DET
biomedich-761	91	20	crystallinity	crystallinity	NOUN
biomedich-761	91	21	of	of	ADP
biomedich-761	91	22	the	the	DET
biomedich-761	91	23	prepared	prepare	VERB
biomedich-761	91	24	systems	system	NOUN
biomedich-761	91	25	further	far	ADV
biomedich-761	91	26	.	.	PUNCT
biomedich-761	92	1	the	the	DET
biomedich-761	92	2	diffractogram	diffractogram	NOUN
biomedich-761	92	3	of	of	ADP
biomedich-761	92	4	pure	pure	ADJ
biomedich-761	92	5	mefa	mefa	PROPN
biomedich-761	92	6	(	(	PUNCT
biomedich-761	92	7	sample	sample	AUX
biomedich-761	92	8	a	a	PRON
biomedich-761	92	9	)	)	PUNCT
biomedich-761	92	10	shows	show	VERB
biomedich-761	92	11	sharp	sharp	ADJ
biomedich-761	92	12	,	,	PUNCT
biomedich-761	92	13	intense	intense	ADJ
biomedich-761	92	14	peaks	peak	NOUN
biomedich-761	92	15	at	at	ADP
biomedich-761	92	16	characteristic	characteristic	ADJ
biomedich-761	92	17	2θ	2θ	NUM
biomedich-761	92	18	values	value	NOUN
biomedich-761	92	19	,	,	PUNCT
biomedich-761	92	20	confirming	confirm	VERB
biomedich-761	92	21	its	its	PRON
biomedich-761	92	22	highly	highly	ADV
biomedich-761	92	23	crystalline	crystalline	ADJ
biomedich-761	92	24	nature	nature	NOUN
biomedich-761	92	25	.	.	PUNCT
biomedich-761	93	1	however	however	ADV
biomedich-761	93	2	,	,	PUNCT
biomedich-761	93	3	these	these	DET
biomedich-761	93	4	peaks	peak	NOUN
biomedich-761	93	5	are	be	AUX
biomedich-761	93	6	markedly	markedly	ADV
biomedich-761	93	7	diminished	diminish	VERB
biomedich-761	93	8	or	or	CCONJ
biomedich-761	93	9	absent	absent	ADJ
biomedich-761	93	10	in	in	ADP
biomedich-761	93	11	the	the	DET
biomedich-761	93	12	solid	solid	ADJ
biomedich-761	93	13	dispersions	dispersion	NOUN
biomedich-761	93	14	(	(	PUNCT
biomedich-761	93	15	samples	sample	NOUN
biomedich-761	93	16	b	b	NOUN
biomedich-761	93	17	to	to	PART
biomedich-761	93	18	e	e	NOUN
biomedich-761	93	19	)	)	PUNCT
biomedich-761	93	20	,	,	PUNCT
biomedich-761	93	21	particularly	particularly	ADV
biomedich-761	93	22	in	in	ADP
biomedich-761	93	23	sample	sample	NOUN
biomedich-761	93	24	c	c	NOUN
biomedich-761	93	25	(	(	PUNCT
biomedich-761	93	26	1:2	1:2	NUM
biomedich-761	93	27	ratio	ratio	NOUN
biomedich-761	93	28	)	)	PUNCT
biomedich-761	93	29	,	,	PUNCT
biomedich-761	93	30	which	which	PRON
biomedich-761	93	31	displays	display	VERB
biomedich-761	93	32	a	a	DET
biomedich-761	93	33	broad	broad	ADJ
biomedich-761	93	34	halo	halo	NOUN
biomedich-761	93	35	pattern	pattern	NOUN
biomedich-761	93	36	instead	instead	ADV
biomedich-761	93	37	of	of	ADP
biomedich-761	93	38	defined	define	VERB
biomedich-761	93	39	peaks	peak	NOUN
biomedich-761	93	40	,	,	PUNCT
biomedich-761	93	41	indicating	indicate	VERB
biomedich-761	93	42	a	a	DET
biomedich-761	93	43	substantial	substantial	ADJ
biomedich-761	93	44	reduction	reduction	NOUN
biomedich-761	93	45	in	in	ADP
biomedich-761	93	46	crystallinity	crystallinity	NOUN
biomedich-761	93	47	and	and	CCONJ
biomedich-761	93	48	transformation	transformation	NOUN
biomedich-761	93	49	to	to	ADP
biomedich-761	93	50	an	an	DET
biomedich-761	93	51	amorphous	amorphous	ADJ
biomedich-761	93	52	state	state	NOUN
biomedich-761	93	53	.	.	PUNCT
biomedich-761	94	1	figure	figure	NOUN
biomedich-761	94	2	3	3	NUM
biomedich-761	94	3	.	.	PUNCT
biomedich-761	94	4	pxrd	pxrd	NOUN
biomedich-761	94	5	patterns	pattern	NOUN
biomedich-761	94	6	of	of	ADP
biomedich-761	94	7	mefa	mefa	PROPN
biomedich-761	94	8	(	(	PUNCT
biomedich-761	94	9	a	a	X
biomedich-761	94	10	)	)	PUNCT
biomedich-761	94	11	,	,	PUNCT
biomedich-761	94	12	ina	ina	PROPN
biomedich-761	94	13	(	(	PUNCT
biomedich-761	94	14	b	b	NOUN
biomedich-761	94	15	)	)	PUNCT
biomedich-761	94	16	,	,	PUNCT
biomedich-761	94	17	and	and	CCONJ
biomedich-761	94	18	solid	solid	ADJ
biomedich-761	94	19	dispersions	dispersion	NOUN
biomedich-761	94	20	in	in	ADP
biomedich-761	94	21	ratios	ratio	NOUN
biomedich-761	94	22	1:1	1:1	NUM
biomedich-761	94	23	(	(	PUNCT
biomedich-761	94	24	c	c	NOUN
biomedich-761	94	25	)	)	PUNCT
biomedich-761	94	26	,	,	PUNCT
biomedich-761	94	27	1:2	1:2	NUM
biomedich-761	94	28	(	(	PUNCT
biomedich-761	94	29	d	d	NOUN
biomedich-761	94	30	)	)	PUNCT
biomedich-761	94	31	,	,	PUNCT
biomedich-761	94	32	and	and	CCONJ
biomedich-761	94	33	2:1	2:1	NUM
biomedich-761	94	34	(	(	PUNCT
biomedich-761	94	35	e	e	NOUN
biomedich-761	94	36	)	)	PUNCT
biomedich-761	94	37	.	.	PUNCT
biomedich-761	95	1	the	the	DET
biomedich-761	95	2	progressive	progressive	ADJ
biomedich-761	95	3	disappearance	disappearance	NOUN
biomedich-761	95	4	of	of	ADP
biomedich-761	95	5	these	these	DET
biomedich-761	95	6	peaks	peak	NOUN
biomedich-761	95	7	with	with	ADP
biomedich-761	95	8	increasing	increase	VERB
biomedich-761	95	9	co	co	ADJ
biomedich-761	95	10	-	-	ADJ
biomedich-761	95	11	former	former	ADJ
biomedich-761	95	12	ratio	ratio	NOUN
biomedich-761	95	13	reflects	reflect	VERB
biomedich-761	95	14	the	the	DET
biomedich-761	95	15	successful	successful	ADJ
biomedich-761	95	16	formation	formation	NOUN
biomedich-761	95	17	of	of	ADP
biomedich-761	95	18	amorphous	amorphous	ADJ
biomedich-761	95	19	solid	solid	ADJ
biomedich-761	95	20	dispersions	dispersion	NOUN
biomedich-761	95	21	and	and	CCONJ
biomedich-761	95	22	confirms	confirm	VERB
biomedich-761	95	23	the	the	DET
biomedich-761	95	24	dsc	dsc	NOUN
biomedich-761	95	25	findings	finding	NOUN
biomedich-761	95	26	.	.	PUNCT
biomedich-761	96	1	according	accord	VERB
biomedich-761	96	2	to	to	ADP
biomedich-761	96	3	sapkal	sapkal	PROPN
biomedich-761	96	4	et	et	PROPN
biomedich-761	96	5	al	al	PROPN
biomedich-761	96	6	.	.	PROPN
biomedich-761	97	1	(	(	PUNCT
biomedich-761	97	2	2018	2018	NUM
biomedich-761	97	3	)	)	PUNCT
biomedich-761	97	4	,	,	PUNCT
biomedich-761	97	5	such	such	ADJ
biomedich-761	97	6	reductions	reduction	NOUN
biomedich-761	97	7	in	in	ADP
biomedich-761	97	8	diffraction	diffraction	NOUN
biomedich-761	97	9	peak	peak	NOUN
biomedich-761	97	10	intensity	intensity	NOUN
biomedich-761	97	11	denote	denote	VERB
biomedich-761	97	12	the	the	DET
biomedich-761	97	13	drug	drug	NOUN
biomedich-761	97	14	’s	’s	PART
biomedich-761	97	15	molecular	molecular	ADJ
biomedich-761	97	16	dispersion	dispersion	NOUN
biomedich-761	97	17	into	into	ADP
biomedich-761	97	18	the	the	DET
biomedich-761	97	19	co	co	NOUN
biomedich-761	97	20	-	-	NOUN
biomedich-761	97	21	former	former	ADJ
biomedich-761	97	22	,	,	PUNCT
biomedich-761	97	23	enhancing	enhance	VERB
biomedich-761	97	24	its	its	PRON
biomedich-761	97	25	solubility	solubility	NOUN
biomedich-761	97	26	due	due	ADP
biomedich-761	97	27	to	to	ADP
biomedich-761	97	28	the	the	DET
biomedich-761	97	29	loss	loss	NOUN
biomedich-761	97	30	of	of	ADP
biomedich-761	97	31	crystal	crystal	NOUN
biomedich-761	97	32	lattice	lattice	PROPN
biomedich-761	97	33	energy	energy	NOUN
biomedich-761	97	34	.	.	PUNCT
biomedich-761	98	1	additionally	additionally	ADV
biomedich-761	98	2	,	,	PUNCT
biomedich-761	98	3	the	the	DET
biomedich-761	98	4	new	new	ADJ
biomedich-761	98	5	halo	halo	NOUN
biomedich-761	98	6	patterns	pattern	NOUN
biomedich-761	98	7	appearing	appear	VERB
biomedich-761	98	8	in	in	ADP
biomedich-761	98	9	samples	sample	NOUN
biomedich-761	98	10	c	c	NOUN
biomedich-761	99	1	and	and	CCONJ
biomedich-761	99	2	d	d	NOUN
biomedich-761	99	3	may	may	AUX
biomedich-761	99	4	suggest	suggest	VERB
biomedich-761	99	5	forming	form	VERB
biomedich-761	99	6	a	a	DET
biomedich-761	99	7	new	new	ADJ
biomedich-761	99	8	amorphous	amorphous	ADJ
biomedich-761	99	9	phase	phase	NOUN
biomedich-761	99	10	or	or	CCONJ
biomedich-761	99	11	co	co	ADJ
biomedich-761	99	12	-	-	ADJ
biomedich-761	99	13	amorphous	amorphous	ADJ
biomedich-761	99	14	system	system	NOUN
biomedich-761	99	15	.	.	PUNCT
biomedich-761	100	1	these	these	DET
biomedich-761	100	2	findings	finding	NOUN
biomedich-761	100	3	are	be	AUX
biomedich-761	100	4	consistent	consistent	ADJ
biomedich-761	100	5	with	with	ADP
biomedich-761	100	6	previous	previous	ADJ
biomedich-761	100	7	studies	study	NOUN
biomedich-761	100	8	on	on	ADP
biomedich-761	100	9	etoricoxib	etoricoxib	ADJ
biomedich-761	100	10	and	and	CCONJ
biomedich-761	100	11	famotidine	famotidine	VERB
biomedich-761	100	12	solid	solid	ADJ
biomedich-761	100	13	dispersions	dispersion	NOUN
biomedich-761	100	14	,	,	PUNCT
biomedich-761	100	15	where	where	SCONJ
biomedich-761	100	16	reduced	reduce	VERB
biomedich-761	100	17	or	or	CCONJ
biomedich-761	100	18	absent	absent	ADJ
biomedich-761	100	19	pxrd	pxrd	NOUN
biomedich-761	100	20	peaks	peak	NOUN
biomedich-761	100	21	signified	signify	VERB
biomedich-761	100	22	enhanced	enhanced	ADJ
biomedich-761	100	23	dispersion	dispersion	NOUN
biomedich-761	100	24	and	and	CCONJ
biomedich-761	100	25	amorphization	amorphization	NOUN
biomedich-761	100	26	(	(	PUNCT
biomedich-761	100	27	chauhan	chauhan	PROPN
biomedich-761	100	28	et	et	PROPN
biomedich-761	100	29	al	al	PROPN
biomedich-761	100	30	.	.	PROPN
biomedich-761	100	31	,	,	PUNCT
biomedich-761	100	32	2005	2005	NUM
biomedich-761	100	33	;	;	PUNCT
biomedich-761	100	34	fitriani	fitriani	PROPN
biomedich-761	100	35	et	et	PROPN
biomedich-761	100	36	al	al	PROPN
biomedich-761	100	37	.	.	PROPN
biomedich-761	100	38	,	,	PUNCT
biomedich-761	100	39	2017	2017	NUM
biomedich-761	100	40	)	)	PUNCT
biomedich-761	100	41	.	.	PUNCT
biomedich-761	101	1	furthermore	furthermore	ADV
biomedich-761	101	2	,	,	PUNCT
biomedich-761	101	3	the	the	DET
biomedich-761	101	4	presence	presence	NOUN
biomedich-761	101	5	of	of	ADP
biomedich-761	101	6	only	only	ADJ
biomedich-761	101	7	low	low	ADJ
biomedich-761	101	8	-	-	PUNCT
biomedich-761	101	9	intensity	intensity	NOUN
biomedich-761	101	10	broad	broad	ADJ
biomedich-761	101	11	peaks	peak	NOUN
biomedich-761	101	12	,	,	PUNCT
biomedich-761	101	13	without	without	ADP
biomedich-761	101	14	the	the	DET
biomedich-761	101	15	sharp	sharp	ADJ
biomedich-761	101	16	reflections	reflection	NOUN
biomedich-761	101	17	typical	typical	ADJ
biomedich-761	101	18	of	of	ADP
biomedich-761	101	19	a	a	DET
biomedich-761	101	20	crystalline	crystalline	ADJ
biomedich-761	101	21	phase	phase	NOUN
biomedich-761	101	22	,	,	PUNCT
biomedich-761	101	23	strongly	strongly	ADV
biomedich-761	101	24	supports	support	VERB
biomedich-761	101	25	the	the	DET
biomedich-761	101	26	solidstate	solidstate	PROPN
biomedich-761	101	27	transformation	transformation	NOUN
biomedich-761	101	28	from	from	ADP
biomedich-761	101	29	a	a	DET
biomedich-761	101	30	crystalline	crystalline	NOUN
biomedich-761	101	31	to	to	ADP
biomedich-761	101	32	an	an	DET
biomedich-761	101	33	amorphous	amorphous	ADJ
biomedich-761	101	34	form	form	NOUN
biomedich-761	101	35	.	.	PUNCT
biomedich-761	102	1	in	in	ADP
biomedich-761	102	2	vitro	vitro	X
biomedich-761	102	3	dissolution	dissolution	NOUN
biomedich-761	102	4	study	study	NOUN
biomedich-761	102	5	the	the	DET
biomedich-761	102	6	dissolution	dissolution	NOUN
biomedich-761	102	7	profiles	profile	NOUN
biomedich-761	102	8	of	of	ADP
biomedich-761	102	9	pure	pure	ADJ
biomedich-761	102	10	mefenamic	mefenamic	ADJ
biomedich-761	102	11	acid	acid	NOUN
biomedich-761	102	12	(	(	PUNCT
biomedich-761	102	13	mefa	mefa	PROPN
biomedich-761	102	14	)	)	PUNCT
biomedich-761	102	15	and	and	CCONJ
biomedich-761	102	16	its	its	PRON
biomedich-761	102	17	crystalline	crystalline	NOUN
biomedich-761	102	18	solid	solid	ADJ
biomedich-761	102	19	dispersions	dispersion	NOUN
biomedich-761	102	20	with	with	ADP
biomedich-761	102	21	isonicotinamide	isonicotinamide	NOUN
biomedich-761	102	22	(	(	PUNCT
biomedich-761	102	23	ina	ina	PROPN
biomedich-761	102	24	)	)	PUNCT
biomedich-761	102	25	in	in	ADP
biomedich-761	102	26	varying	vary	VERB
biomedich-761	102	27	molar	molar	ADJ
biomedich-761	102	28	ratios	ratio	NOUN
biomedich-761	102	29	are	be	AUX
biomedich-761	102	30	illustrated	illustrate	VERB
biomedich-761	102	31	in	in	ADP
biomedich-761	102	32	figure	figure	NOUN
biomedich-761	102	33	image.png	image.png	PRON
biomedich-761	102	34	.	.	PUNCT
biomedich-761	103	1	pure	pure	ADJ
biomedich-761	103	2	mefa	mefa	PROPN
biomedich-761	103	3	exhibited	exhibit	VERB
biomedich-761	103	4	poor	poor	ADJ
biomedich-761	103	5	dissolution	dissolution	NOUN
biomedich-761	103	6	,	,	PUNCT
biomedich-761	103	7	reaching	reach	VERB
biomedich-761	103	8	only	only	ADV
biomedich-761	103	9	about	about	ADV
biomedich-761	103	10	23.16	23.16	NUM
biomedich-761	103	11	%	%	NOUN
biomedich-761	103	12	drug	drug	NOUN
biomedich-761	103	13	release	release	NOUN
biomedich-761	103	14	after	after	ADP
biomedich-761	103	15	60	60	NUM
biomedich-761	103	16	minutes	minute	NOUN
biomedich-761	103	17	,	,	PUNCT
biomedich-761	103	18	consistent	consistent	ADJ
biomedich-761	103	19	with	with	ADP
biomedich-761	103	20	its	its	PRON
biomedich-761	103	21	known	know	VERB
biomedich-761	103	22	low	low	ADJ
biomedich-761	103	23	aqueous	aqueous	ADJ
biomedich-761	103	24	solubility	solubility	NOUN
biomedich-761	103	25	.	.	PUNCT
biomedich-761	104	1	in	in	ADP
biomedich-761	104	2	contrast	contrast	NOUN
biomedich-761	104	3	,	,	PUNCT
biomedich-761	104	4	all	all	DET
biomedich-761	104	5	mefa	mefa	NOUN
biomedich-761	104	6	:	:	PUNCT
biomedich-761	104	7	ina	ina	PROPN
biomedich-761	104	8	dispersions	dispersion	NOUN
biomedich-761	104	9	demonstrated	demonstrate	VERB
biomedich-761	104	10	enhanced	enhanced	ADJ
biomedich-761	104	11	dissolution	dissolution	NOUN
biomedich-761	104	12	,	,	PUNCT
biomedich-761	104	13	with	with	ADP
biomedich-761	104	14	the	the	DET
biomedich-761	104	15	1:2	1:2	NUM
biomedich-761	104	16	ratio	ratio	NOUN
biomedich-761	104	17	achieving	achieve	VERB
biomedich-761	104	18	the	the	DET
biomedich-761	104	19	highest	high	ADJ
biomedich-761	104	20	release	release	NOUN
biomedich-761	104	21	,	,	PUNCT
biomedich-761	104	22	approximately	approximately	ADV
biomedich-761	104	23	58.51	58.51	NUM
biomedich-761	104	24	%	%	NOUN
biomedich-761	104	25	within	within	ADP
biomedich-761	104	26	60	60	NUM
biomedich-761	104	27	minutes	minute	NOUN
biomedich-761	104	28	.	.	PUNCT
biomedich-761	105	1	figure	figure	VERB
biomedich-761	105	2	4	4	NUM
biomedich-761	105	3	.	.	PUNCT
biomedich-761	106	1	dissolution	dissolution	ADJ
biomedich-761	106	2	profiles	profile	NOUN
biomedich-761	106	3	of	of	ADP
biomedich-761	106	4	mefa	mefa	PROPN
biomedich-761	106	5	and	and	CCONJ
biomedich-761	106	6	its	its	PRON
biomedich-761	106	7	solid	solid	ADJ
biomedich-761	106	8	dispersions	dispersion	NOUN
biomedich-761	106	9	with	with	ADP
biomedich-761	106	10	ina	ina	PROPN
biomedich-761	106	11	at	at	ADP
biomedich-761	106	12	molar	molar	ADJ
biomedich-761	106	13	ratios	ratio	NOUN
biomedich-761	106	14	of	of	ADP
biomedich-761	106	15	1:1	1:1	NUM
biomedich-761	106	16	,	,	PUNCT
biomedich-761	106	17	1:2	1:2	NUM
biomedich-761	106	18	,	,	PUNCT
biomedich-761	106	19	and	and	CCONJ
biomedich-761	106	20	2:1	2:1	NUM
biomedich-761	106	21	.	.	PUNCT
biomedich-761	107	1	the	the	DET
biomedich-761	107	2	1:2	1:2	NUM
biomedich-761	107	3	system	system	NOUN
biomedich-761	107	4	significantly	significantly	ADV
biomedich-761	107	5	outperformed	outperform	VERB
biomedich-761	107	6	the	the	DET
biomedich-761	107	7	1:1	1:1	NUM
biomedich-761	107	8	(	(	PUNCT
biomedich-761	107	9	37.53	37.53	NUM
biomedich-761	107	10	%	%	NOUN
biomedich-761	107	11	)	)	PUNCT
biomedich-761	107	12	and	and	CCONJ
biomedich-761	107	13	2:1	2:1	NUM
biomedich-761	107	14	(	(	PUNCT
biomedich-761	107	15	25.80	25.80	NUM
biomedich-761	107	16	%	%	NOUN
biomedich-761	107	17	)	)	PUNCT
biomedich-761	107	18	ratios	ratio	NOUN
biomedich-761	107	19	,	,	PUNCT
biomedich-761	107	20	underscoring	underscore	VERB
biomedich-761	107	21	the	the	DET
biomedich-761	107	22	importance	importance	NOUN
biomedich-761	107	23	of	of	ADP
biomedich-761	107	24	co	co	ADJ
biomedich-761	107	25	-	-	ADJ
biomedich-761	107	26	former	former	ADJ
biomedich-761	107	27	concentration	concentration	NOUN
biomedich-761	107	28	in	in	ADP
biomedich-761	107	29	facilitating	facilitate	VERB
biomedich-761	107	30	drug	drug	NOUN
biomedich-761	107	31	solubilization	solubilization	NOUN
biomedich-761	107	32	.	.	PUNCT
biomedich-761	108	1	this	this	DET
biomedich-761	108	2	enhancement	enhancement	NOUN
biomedich-761	108	3	correlates	correlate	VERB
biomedich-761	108	4	with	with	ADP
biomedich-761	108	5	findings	finding	NOUN
biomedich-761	108	6	from	from	ADP
biomedich-761	108	7	pxrd	pxrd	NOUN
biomedich-761	108	8	and	and	CCONJ
biomedich-761	108	9	dsc	dsc	NOUN
biomedich-761	108	10	analyses	analysis	NOUN
biomedich-761	108	11	,	,	PUNCT
biomedich-761	108	12	which	which	PRON
biomedich-761	108	13	indicated	indicate	VERB
biomedich-761	108	14	a	a	DET
biomedich-761	108	15	shift	shift	NOUN
biomedich-761	108	16	from	from	ADP
biomedich-761	108	17	a	a	DET
biomedich-761	108	18	crystalline	crystalline	NOUN
biomedich-761	108	19	to	to	ADP
biomedich-761	108	20	a	a	DET
biomedich-761	108	21	more	more	ADV
biomedich-761	108	22	amorphous	amorphous	ADJ
biomedich-761	108	23	or	or	CCONJ
biomedich-761	108	24	molecularly	molecularly	ADV
biomedich-761	108	25	dispersed	disperse	VERB
biomedich-761	108	26	state	state	NOUN
biomedich-761	108	27	.	.	PUNCT
biomedich-761	109	1	the	the	DET
biomedich-761	109	2	absence	absence	NOUN
biomedich-761	109	3	of	of	ADP
biomedich-761	109	4	distinct	distinct	ADJ
biomedich-761	109	5	melting	melting	NOUN
biomedich-761	109	6	endotherms	endotherm	NOUN
biomedich-761	109	7	and	and	CCONJ
biomedich-761	109	8	the	the	DET
biomedich-761	109	9	appearance	appearance	NOUN
biomedich-761	109	10	of	of	ADP
biomedich-761	109	11	a	a	DET
biomedich-761	109	12	broad	broad	ADJ
biomedich-761	109	13	glass	glass	NOUN
biomedich-761	109	14	transition	transition	NOUN
biomedich-761	109	15	in	in	ADP
biomedich-761	109	16	dsc	dsc	NOUN
biomedich-761	109	17	thermograms	thermogram	NOUN
biomedich-761	109	18	suggest	suggest	VERB
biomedich-761	109	19	that	that	SCONJ
biomedich-761	109	20	the	the	DET
biomedich-761	109	21	drug	drug	NOUN
biomedich-761	109	22	is	be	AUX
biomedich-761	109	23	well	well	ADV
biomedich-761	109	24	integrated	integrate	VERB
biomedich-761	109	25	at	at	ADP
biomedich-761	109	26	the	the	DET
biomedich-761	109	27	molecular	molecular	ADJ
biomedich-761	109	28	level	level	NOUN
biomedich-761	109	29	.	.	PUNCT
biomedich-761	110	1	the	the	DET
biomedich-761	110	2	improved	improve	VERB
biomedich-761	110	3	solubility	solubility	NOUN
biomedich-761	110	4	and	and	CCONJ
biomedich-761	110	5	dissolution	dissolution	NOUN
biomedich-761	110	6	profiles	profile	NOUN
biomedich-761	110	7	observed	observe	VERB
biomedich-761	110	8	across	across	ADP
biomedich-761	110	9	the	the	DET
biomedich-761	110	10	solid	solid	ADJ
biomedich-761	110	11	dispersions	dispersion	NOUN
biomedich-761	110	12	can	can	AUX
biomedich-761	110	13	be	be	AUX
biomedich-761	110	14	attributed	attribute	VERB
biomedich-761	110	15	to	to	ADP
biomedich-761	110	16	the	the	DET
biomedich-761	110	17	synergistic	synergistic	ADJ
biomedich-761	110	18	effects	effect	NOUN
biomedich-761	110	19	of	of	ADP
biomedich-761	110	20	molecular	molecular	ADJ
biomedich-761	110	21	dispersion	dispersion	NOUN
biomedich-761	110	22	,	,	PUNCT
biomedich-761	110	23	hydrogen	hydrogen	NOUN
biomedich-761	110	24	bonding	bonding	NOUN
biomedich-761	110	25	,	,	PUNCT
biomedich-761	110	26	and	and	CCONJ
biomedich-761	110	27	reduced	reduced	ADJ
biomedich-761	110	28	crystallinity	crystallinity	NOUN
biomedich-761	110	29	.	.	PUNCT
biomedich-761	111	1	the	the	DET
biomedich-761	111	2	ftir	ftir	PROPN
biomedich-761	111	3	spectra	spectra	PROPN
biomedich-761	111	4	demonstrated	demonstrate	VERB
biomedich-761	111	5	significant	significant	ADJ
biomedich-761	111	6	intermolecular	intermolecular	ADJ
biomedich-761	111	7	interactions	interaction	NOUN
biomedich-761	111	8	,	,	PUNCT
biomedich-761	111	9	particularly	particularly	ADV
biomedich-761	111	10	in	in	ADP
biomedich-761	111	11	the	the	DET
biomedich-761	111	12	1:2	1:2	NUM
biomedich-761	111	13	system	system	NOUN
biomedich-761	111	14	,	,	PUNCT
biomedich-761	111	15	where	where	SCONJ
biomedich-761	111	16	characteristic	characteristic	ADJ
biomedich-761	111	17	drug	drug	NOUN
biomedich-761	111	18	peaks	peak	NOUN
biomedich-761	111	19	were	be	AUX
biomedich-761	111	20	either	either	CCONJ
biomedich-761	111	21	shifted	shift	VERB
biomedich-761	111	22	or	or	CCONJ
biomedich-761	111	23	suppressed	suppress	VERB
biomedich-761	111	24	.	.	PUNCT
biomedich-761	112	1	dsc	dsc	NOUN
biomedich-761	112	2	confirmed	confirm	VERB
biomedich-761	112	3	the	the	DET
biomedich-761	112	4	transition	transition	NOUN
biomedich-761	112	5	from	from	ADP
biomedich-761	112	6	crystalline	crystalline	NOUN
biomedich-761	112	7	to	to	ADP
biomedich-761	112	8	amorphous	amorphous	ADJ
biomedich-761	112	9	form	form	NOUN
biomedich-761	112	10	through	through	ADP
biomedich-761	112	11	the	the	DET
biomedich-761	112	12	disappearance	disappearance	NOUN
biomedich-761	112	13	of	of	ADP
biomedich-761	112	14	melting	melt	VERB
biomedich-761	112	15	endotherms	endotherm	NOUN
biomedich-761	112	16	and	and	CCONJ
biomedich-761	112	17	the	the	DET
biomedich-761	112	18	appearance	appearance	NOUN
biomedich-761	112	19	of	of	ADP
biomedich-761	112	20	a	a	DET
biomedich-761	112	21	single	single	ADJ
biomedich-761	112	22	tg	tg	PROPN
biomedich-761	112	23	.	.	PUNCT
biomedich-761	112	24	pxrd	pxrd	PROPN
biomedich-761	112	25	further	far	ADV
biomedich-761	112	26	corroborated	corroborate	VERB
biomedich-761	112	27	these	these	DET
biomedich-761	112	28	findings	finding	NOUN
biomedich-761	112	29	by	by	ADP
biomedich-761	112	30	showing	show	VERB
biomedich-761	112	31	decreased	decrease	VERB
biomedich-761	112	32	intensity	intensity	NOUN
biomedich-761	112	33	in	in	ADP
biomedich-761	112	34	the	the	DET
biomedich-761	112	35	same	same	ADJ
biomedich-761	112	36	samples	sample	NOUN
biomedich-761	112	37	.	.	PUNCT
biomedich-761	113	1	these	these	DET
biomedich-761	113	2	solid	solid	ADJ
biomedich-761	113	3	-	-	PUNCT
biomedich-761	113	4	state	state	NOUN
biomedich-761	113	5	modifications	modification	NOUN
biomedich-761	113	6	have	have	AUX
biomedich-761	113	7	been	be	AUX
biomedich-761	113	8	shown	show	VERB
biomedich-761	113	9	to	to	PART
biomedich-761	113	10	contribute	contribute	VERB
biomedich-761	113	11	to	to	ADP
biomedich-761	113	12	enhanced	enhanced	ADJ
biomedich-761	113	13	dissolution	dissolution	NOUN
biomedich-761	113	14	rates	rate	NOUN
biomedich-761	113	15	directly	directly	ADV
biomedich-761	113	16	,	,	PUNCT
biomedich-761	113	17	a	a	DET
biomedich-761	113	18	trend	trend	NOUN
biomedich-761	113	19	indra	indra	PROPN
biomedich-761	113	20	et	et	NOUN
biomedich-761	113	21	al	al	PROPN
biomedich-761	113	22	.	.	PROPN
biomedich-761	113	23	–	–	PUNCT
biomedich-761	113	24	crystalline	crystalline	X
biomedich-761	113	25	solid	solid	ADJ
biomedich-761	113	26	dispersion	dispersion	NOUN
biomedich-761	113	27	for	for	ADP
biomedich-761	113	28	mefenamic	mefenamic	ADJ
biomedich-761	113	29	acid	acid	NOUN
biomedich-761	113	30	605	605	NUM
biomedich-761	113	31	consistent	consistent	ADJ
biomedich-761	113	32	with	with	ADP
biomedich-761	113	33	prior	prior	ADJ
biomedich-761	113	34	studies	study	NOUN
biomedich-761	113	35	on	on	ADP
biomedich-761	113	36	poorly	poorly	ADV
biomedich-761	113	37	soluble	soluble	ADJ
biomedich-761	113	38	nsaids	nsaid	NOUN
biomedich-761	113	39	,	,	PUNCT
biomedich-761	113	40	such	such	ADJ
biomedich-761	113	41	as	as	ADP
biomedich-761	113	42	etoricoxib	etoricoxib	ADJ
biomedich-761	113	43	,	,	PUNCT
biomedich-761	113	44	naproxen	naproxen	NOUN
biomedich-761	113	45	,	,	PUNCT
biomedich-761	113	46	and	and	CCONJ
biomedich-761	113	47	fenofibrate	fenofibrate	NOUN
biomedich-761	113	48	(	(	PUNCT
biomedich-761	113	49	liu	liu	PROPN
biomedich-761	113	50	et	et	PROPN
biomedich-761	113	51	al	al	PROPN
biomedich-761	113	52	.	.	PROPN
biomedich-761	113	53	,	,	PUNCT
biomedich-761	113	54	2015	2015	NUM
biomedich-761	113	55	;	;	PUNCT
biomedich-761	113	56	mardiyanto	mardiyanto	PROPN
biomedich-761	113	57	et	et	PROPN
biomedich-761	113	58	al	al	PROPN
biomedich-761	113	59	.	.	PROPN
biomedich-761	113	60	,	,	PUNCT
biomedich-761	113	61	2020	2020	NUM
biomedich-761	113	62	;	;	PUNCT
biomedich-761	113	63	sharma	sharma	PROPN
biomedich-761	113	64	et	et	PROPN
biomedich-761	113	65	al	al	PROPN
biomedich-761	113	66	.	.	PROPN
biomedich-761	113	67	,	,	PUNCT
biomedich-761	113	68	2017	2017	NUM
biomedich-761	113	69	)	)	PUNCT
biomedich-761	113	70	.	.	PUNCT
biomedich-761	114	1	moreover	moreover	ADV
biomedich-761	114	2	,	,	PUNCT
biomedich-761	114	3	the	the	DET
biomedich-761	114	4	increased	increase	VERB
biomedich-761	114	5	dissolution	dissolution	NOUN
biomedich-761	114	6	rate	rate	NOUN
biomedich-761	114	7	observed	observe	VERB
biomedich-761	114	8	in	in	ADP
biomedich-761	114	9	the	the	DET
biomedich-761	114	10	optimal	optimal	ADJ
biomedich-761	114	11	1:2	1:2	NUM
biomedich-761	114	12	formulation	formulation	NOUN
biomedich-761	114	13	illustrates	illustrate	VERB
biomedich-761	114	14	the	the	DET
biomedich-761	114	15	importance	importance	NOUN
biomedich-761	114	16	of	of	ADP
biomedich-761	114	17	identifying	identify	VERB
biomedich-761	114	18	and	and	CCONJ
biomedich-761	114	19	applying	apply	VERB
biomedich-761	114	20	the	the	DET
biomedich-761	114	21	appropriate	appropriate	ADJ
biomedich-761	114	22	co	co	ADJ
biomedich-761	114	23	-	-	ADJ
biomedich-761	114	24	former	former	ADJ
biomedich-761	114	25	ratio	ratio	NOUN
biomedich-761	114	26	to	to	PART
biomedich-761	114	27	improve	improve	VERB
biomedich-761	114	28	maximal	maximal	ADJ
biomedich-761	114	29	solubility	solubility	NOUN
biomedich-761	114	30	.	.	PUNCT
biomedich-761	115	1	together	together	ADV
biomedich-761	115	2	,	,	PUNCT
biomedich-761	115	3	these	these	DET
biomedich-761	115	4	findings	finding	NOUN
biomedich-761	115	5	substantiate	substantiate	VERB
biomedich-761	115	6	the	the	DET
biomedich-761	115	7	role	role	NOUN
biomedich-761	115	8	of	of	ADP
biomedich-761	115	9	solid	solid	ADJ
biomedich-761	115	10	dispersion	dispersion	NOUN
biomedich-761	115	11	as	as	ADP
biomedich-761	115	12	an	an	DET
biomedich-761	115	13	effective	effective	ADJ
biomedich-761	115	14	strategy	strategy	NOUN
biomedich-761	115	15	for	for	ADP
biomedich-761	115	16	enhancing	enhance	VERB
biomedich-761	115	17	the	the	DET
biomedich-761	115	18	bioavailability	bioavailability	NOUN
biomedich-761	115	19	of	of	ADP
biomedich-761	115	20	poorly	poorly	ADV
biomedich-761	115	21	soluble	soluble	ADJ
biomedich-761	115	22	drugs	drug	NOUN
biomedich-761	115	23	such	such	ADJ
biomedich-761	115	24	as	as	ADP
biomedich-761	115	25	mefa	mefa	PROPN
biomedich-761	115	26	.	.	PUNCT
biomedich-761	116	1	they	they	PRON
biomedich-761	116	2	also	also	ADV
biomedich-761	116	3	highlight	highlight	VERB
biomedich-761	116	4	the	the	DET
biomedich-761	116	5	necessity	necessity	NOUN
biomedich-761	116	6	of	of	ADP
biomedich-761	116	7	comprehensive	comprehensive	ADJ
biomedich-761	116	8	solidstate	solidstate	PROPN
biomedich-761	116	9	characterization	characterization	NOUN
biomedich-761	116	10	to	to	PART
biomedich-761	116	11	elucidate	elucidate	VERB
biomedich-761	116	12	the	the	DET
biomedich-761	116	13	mechanisms	mechanism	NOUN
biomedich-761	116	14	behind	behind	ADP
biomedich-761	116	15	dissolution	dissolution	NOUN
biomedich-761	116	16	enhancement	enhancement	NOUN
biomedich-761	116	17	and	and	CCONJ
biomedich-761	116	18	to	to	PART
biomedich-761	116	19	inform	inform	VERB
biomedich-761	116	20	formulation	formulation	NOUN
biomedich-761	116	21	development	development	NOUN
biomedich-761	116	22	decisions	decision	NOUN
biomedich-761	116	23	.	.	PUNCT
biomedich-761	117	1	conclusions	conclusion	NOUN
biomedich-761	117	2	this	this	DET
biomedich-761	117	3	study	study	NOUN
biomedich-761	117	4	demonstrates	demonstrate	VERB
biomedich-761	117	5	the	the	DET
biomedich-761	117	6	effectiveness	effectiveness	NOUN
biomedich-761	117	7	of	of	ADP
biomedich-761	117	8	csds	csds	NOUN
biomedich-761	117	9	using	use	VERB
biomedich-761	117	10	solvent	solvent	ADJ
biomedich-761	117	11	evaporation	evaporation	NOUN
biomedich-761	117	12	and	and	CCONJ
biomedich-761	117	13	co	co	ADJ
biomedich-761	117	14	-	-	ADJ
biomedich-761	117	15	grinding	grind	VERB
biomedich-761	117	16	techniques	technique	NOUN
biomedich-761	117	17	to	to	PART
biomedich-761	117	18	enhance	enhance	VERB
biomedich-761	117	19	the	the	DET
biomedich-761	117	20	solubility	solubility	NOUN
biomedich-761	117	21	and	and	CCONJ
biomedich-761	117	22	dissolution	dissolution	NOUN
biomedich-761	117	23	rate	rate	NOUN
biomedich-761	117	24	of	of	ADP
biomedich-761	117	25	mefa	mefa	PROPN
biomedich-761	117	26	.	.	PUNCT
biomedich-761	118	1	among	among	ADP
biomedich-761	118	2	the	the	DET
biomedich-761	118	3	formulations	formulation	NOUN
biomedich-761	118	4	tested	test	VERB
biomedich-761	118	5	,	,	PUNCT
biomedich-761	118	6	the	the	DET
biomedich-761	118	7	1:2	1:2	NUM
biomedich-761	118	8	drug	drug	NOUN
biomedich-761	118	9	-	-	PUNCT
biomedich-761	118	10	to	to	ADP
biomedich-761	118	11	-	-	PUNCT
biomedich-761	118	12	ina	ina	PROPN
biomedich-761	118	13	ratio	ratio	NOUN
biomedich-761	118	14	produced	produce	VERB
biomedich-761	118	15	the	the	DET
biomedich-761	118	16	most	most	ADV
biomedich-761	118	17	significant	significant	ADJ
biomedich-761	118	18	improvement	improvement	NOUN
biomedich-761	118	19	in	in	ADP
biomedich-761	118	20	dissolution	dissolution	NOUN
biomedich-761	118	21	,	,	PUNCT
biomedich-761	118	22	supported	support	VERB
biomedich-761	118	23	by	by	ADP
biomedich-761	118	24	comprehensive	comprehensive	ADJ
biomedich-761	118	25	physicochemical	physicochemical	ADJ
biomedich-761	118	26	analyses	analysis	NOUN
biomedich-761	118	27	.	.	PUNCT
biomedich-761	119	1	differential	differential	ADJ
biomedich-761	119	2	scanning	scanning	NOUN
biomedich-761	119	3	calorimetry	calorimetry	NOUN
biomedich-761	119	4	revealed	reveal	VERB
biomedich-761	119	5	the	the	DET
biomedich-761	119	6	disappearance	disappearance	NOUN
biomedich-761	119	7	of	of	ADP
biomedich-761	119	8	the	the	DET
biomedich-761	119	9	drug	drug	NOUN
biomedich-761	119	10	’s	’s	PART
biomedich-761	119	11	melting	melting	NOUN
biomedich-761	119	12	peak	peak	NOUN
biomedich-761	119	13	and	and	CCONJ
biomedich-761	119	14	the	the	DET
biomedich-761	119	15	appearance	appearance	NOUN
biomedich-761	119	16	of	of	ADP
biomedich-761	119	17	a	a	DET
biomedich-761	119	18	single	single	ADJ
biomedich-761	119	19	glass	glass	NOUN
biomedich-761	119	20	transition	transition	NOUN
biomedich-761	119	21	temperature	temperature	NOUN
biomedich-761	119	22	,	,	PUNCT
biomedich-761	119	23	indicating	indicate	VERB
biomedich-761	119	24	reduced	reduce	VERB
biomedich-761	119	25	crystallinity	crystallinity	NOUN
biomedich-761	119	26	and	and	CCONJ
biomedich-761	119	27	enhanced	enhance	VERB
biomedich-761	119	28	miscibility	miscibility	NOUN
biomedich-761	119	29	.	.	PUNCT
biomedich-761	120	1	pxrd	pxrd	PROPN
biomedich-761	120	2	patterns	pattern	NOUN
biomedich-761	120	3	showed	show	VERB
biomedich-761	120	4	a	a	DET
biomedich-761	120	5	broad	broad	ADJ
biomedich-761	120	6	halo	halo	NOUN
biomedich-761	120	7	,	,	PUNCT
biomedich-761	120	8	confirming	confirm	VERB
biomedich-761	120	9	partial	partial	ADJ
biomedich-761	120	10	or	or	CCONJ
biomedich-761	120	11	complete	complete	ADJ
biomedich-761	120	12	amorphization	amorphization	NOUN
biomedich-761	120	13	,	,	PUNCT
biomedich-761	120	14	while	while	SCONJ
biomedich-761	120	15	ftir	ftir	PROPN
biomedich-761	120	16	spectra	spectra	PROPN
biomedich-761	120	17	suggested	suggest	VERB
biomedich-761	120	18	the	the	DET
biomedich-761	120	19	formation	formation	NOUN
biomedich-761	120	20	of	of	ADP
biomedich-761	120	21	intermolecular	intermolecular	ADJ
biomedich-761	120	22	hydrogen	hydrogen	NOUN
biomedich-761	120	23	bonds	bond	NOUN
biomedich-761	120	24	between	between	ADP
biomedich-761	120	25	the	the	DET
biomedich-761	120	26	drug	drug	NOUN
biomedich-761	120	27	and	and	CCONJ
biomedich-761	120	28	the	the	DET
biomedich-761	120	29	co	co	NOUN
biomedich-761	120	30	-	-	NOUN
biomedich-761	120	31	former	former	ADJ
biomedich-761	120	32	.	.	PUNCT
biomedich-761	121	1	these	these	DET
biomedich-761	121	2	findings	finding	NOUN
biomedich-761	121	3	underscore	underscore	VERB
biomedich-761	121	4	the	the	DET
biomedich-761	121	5	critical	critical	ADJ
biomedich-761	121	6	role	role	NOUN
biomedich-761	121	7	of	of	ADP
biomedich-761	121	8	smallmolecule	smallmolecule	NOUN
biomedich-761	121	9	co	co	ADJ
biomedich-761	121	10	-	-	ADJ
biomedich-761	121	11	former	former	ADJ
biomedich-761	121	12	ratios	ratio	NOUN
biomedich-761	121	13	in	in	ADP
biomedich-761	121	14	modulating	modulate	VERB
biomedich-761	121	15	solid	solid	ADJ
biomedich-761	121	16	-	-	PUNCT
biomedich-761	121	17	state	state	NOUN
biomedich-761	121	18	properties	property	NOUN
biomedich-761	121	19	and	and	CCONJ
biomedich-761	121	20	improving	improve	VERB
biomedich-761	121	21	drug	drug	NOUN
biomedich-761	121	22	performance	performance	NOUN
biomedich-761	121	23	.	.	PUNCT
biomedich-761	122	1	importantly	importantly	ADV
biomedich-761	122	2	,	,	PUNCT
biomedich-761	122	3	this	this	DET
biomedich-761	122	4	study	study	NOUN
biomedich-761	122	5	expands	expand	VERB
biomedich-761	122	6	the	the	DET
biomedich-761	122	7	application	application	NOUN
biomedich-761	122	8	of	of	ADP
biomedich-761	122	9	csds	csds	NOUN
biomedich-761	122	10	beyond	beyond	ADP
biomedich-761	122	11	polymeric	polymeric	ADJ
biomedich-761	122	12	systems	system	NOUN
biomedich-761	122	13	,	,	PUNCT
biomedich-761	122	14	highlighting	highlight	VERB
biomedich-761	122	15	the	the	DET
biomedich-761	122	16	potential	potential	NOUN
biomedich-761	122	17	of	of	ADP
biomedich-761	122	18	ina	ina	PROPN
biomedich-761	122	19	as	as	ADP
biomedich-761	122	20	a	a	DET
biomedich-761	122	21	non	non	ADJ
biomedich-761	122	22	-	-	ADJ
biomedich-761	122	23	polymeric	polymeric	ADJ
biomedich-761	122	24	solubility	solubility	NOUN
biomedich-761	122	25	enhancer	enhancer	NOUN
biomedich-761	122	26	.	.	PUNCT
biomedich-761	123	1	the	the	DET
biomedich-761	123	2	analytical	analytical	ADJ
biomedich-761	123	3	data	datum	NOUN
biomedich-761	123	4	collectively	collectively	ADV
biomedich-761	123	5	confirm	confirm	VERB
biomedich-761	123	6	the	the	DET
biomedich-761	123	7	successful	successful	ADJ
biomedich-761	123	8	formation	formation	NOUN
biomedich-761	123	9	of	of	ADP
biomedich-761	123	10	molecularly	molecularly	ADV
biomedich-761	123	11	dispersed	disperse	VERB
biomedich-761	123	12	systems	system	NOUN
biomedich-761	123	13	that	that	PRON
biomedich-761	123	14	resist	resist	VERB
biomedich-761	123	15	recrystallization	recrystallization	NOUN
biomedich-761	123	16	and	and	CCONJ
biomedich-761	123	17	promote	promote	VERB
biomedich-761	123	18	rapid	rapid	ADJ
biomedich-761	123	19	dissolution	dissolution	NOUN
biomedich-761	123	20	.	.	PUNCT
biomedich-761	124	1	future	future	ADJ
biomedich-761	124	2	investigations	investigation	NOUN
biomedich-761	124	3	should	should	AUX
biomedich-761	124	4	evaluate	evaluate	VERB
biomedich-761	124	5	long	long	ADJ
biomedich-761	124	6	-	-	PUNCT
biomedich-761	124	7	term	term	NOUN
biomedich-761	124	8	physical	physical	ADJ
biomedich-761	124	9	stability	stability	NOUN
biomedich-761	124	10	,	,	PUNCT
biomedich-761	124	11	in	in	ADP
biomedich-761	124	12	vivo	vivo	ADJ
biomedich-761	124	13	bioavailability	bioavailability	NOUN
biomedich-761	124	14	,	,	PUNCT
biomedich-761	124	15	and	and	CCONJ
biomedich-761	124	16	alternative	alternative	ADJ
biomedich-761	124	17	gras	gra	NOUN
biomedich-761	124	18	-	-	PUNCT
biomedich-761	124	19	status	status	NOUN
biomedich-761	124	20	co	co	NOUN
biomedich-761	124	21	-	-	NOUN
biomedich-761	124	22	formers	former	NOUN
biomedich-761	124	23	or	or	CCONJ
biomedich-761	124	24	surfactants	surfactant	NOUN
biomedich-761	124	25	to	to	PART
biomedich-761	124	26	further	far	ADV
biomedich-761	124	27	optimize	optimize	VERB
biomedich-761	124	28	formulation	formulation	NOUN
biomedich-761	124	29	performance	performance	NOUN
biomedich-761	124	30	for	for	ADP
biomedich-761	124	31	poorly	poorly	ADV
biomedich-761	124	32	soluble	soluble	ADJ
biomedich-761	124	33	non	non	ADJ
biomedich-761	124	34	-	-	ADJ
biomedich-761	124	35	steroidal	steroidal	ADJ
biomedich-761	124	36	anti	anti	ADJ
biomedich-761	124	37	-	-	ADJ
biomedich-761	124	38	inflammatory	inflammatory	ADJ
biomedich-761	124	39	drugs	drug	NOUN
biomedich-761	124	40	such	such	ADJ
biomedich-761	124	41	as	as	ADP
biomedich-761	124	42	mefa	mefa	PROPN
biomedich-761	124	43	.	.	PUNCT
biomedich-761	125	1	acknowledgements	acknowledgement	NOUN
biomedich-761	125	2	:	:	PUNCT
biomedich-761	125	3	the	the	DET
biomedich-761	125	4	authors	author	NOUN
biomedich-761	125	5	would	would	AUX
biomedich-761	125	6	like	like	VERB
biomedich-761	125	7	to	to	PART
biomedich-761	125	8	express	express	VERB
biomedich-761	125	9	their	their	PRON
biomedich-761	125	10	sincere	sincere	ADJ
biomedich-761	125	11	gratitude	gratitude	NOUN
biomedich-761	125	12	to	to	ADP
biomedich-761	125	13	the	the	DET
biomedich-761	125	14	institute	institute	NOUN
biomedich-761	125	15	for	for	ADP
biomedich-761	125	16	research	research	NOUN
biomedich-761	125	17	and	and	CCONJ
biomedich-761	125	18	community	community	NOUN
biomedich-761	125	19	service	service	NOUN
biomedich-761	125	20	and	and	CCONJ
biomedich-761	125	21	the	the	DET
biomedich-761	125	22	department	department	NOUN
biomedich-761	125	23	of	of	ADP
biomedich-761	125	24	pharmacy	pharmacy	NOUN
biomedich-761	125	25	,	,	PUNCT
biomedich-761	125	26	universitas	universita	NOUN
biomedich-761	125	27	bakti	bakti	PROPN
biomedich-761	125	28	tunas	tunas	PROPN
biomedich-761	125	29	husada	husada	PROPN
biomedich-761	125	30	,	,	PUNCT
biomedich-761	125	31	for	for	ADP
biomedich-761	125	32	their	their	PRON
biomedich-761	125	33	valuable	valuable	ADJ
biomedich-761	125	34	support	support	NOUN
biomedich-761	125	35	and	and	CCONJ
biomedich-761	125	36	facilitation	facilitation	NOUN
biomedich-761	125	37	throughout	throughout	ADP
biomedich-761	125	38	this	this	DET
biomedich-761	125	39	research	research	NOUN
biomedich-761	125	40	.	.	PUNCT
biomedich-761	126	1	their	their	PRON
biomedich-761	126	2	contributions	contribution	NOUN
biomedich-761	126	3	in	in	ADP
biomedich-761	126	4	providing	provide	VERB
biomedich-761	126	5	resources	resource	NOUN
biomedich-761	126	6	,	,	PUNCT
biomedich-761	126	7	guidance	guidance	NOUN
biomedich-761	126	8	,	,	PUNCT
biomedich-761	126	9	and	and	CCONJ
biomedich-761	126	10	infrastructure	infrastructure	NOUN
biomedich-761	126	11	were	be	AUX
biomedich-761	126	12	instrumental	instrumental	ADJ
biomedich-761	126	13	to	to	ADP
biomedich-761	126	14	the	the	DET
biomedich-761	126	15	successful	successful	ADJ
biomedich-761	126	16	completion	completion	NOUN
biomedich-761	126	17	of	of	ADP
biomedich-761	126	18	this	this	DET
biomedich-761	126	19	study	study	NOUN
biomedich-761	126	20	.	.	PUNCT
biomedich-761	127	1	authors	author	NOUN
biomedich-761	127	2	’	'	PUNCT
biomedich-761	127	3	contributions	contribution	NOUN
biomedich-761	127	4	:	:	PUNCT
biomedich-761	127	5	indra	indra	NOUN
biomedich-761	127	6	,	,	PUNCT
biomedich-761	127	7	ade	ade	PROPN
biomedich-761	127	8	yeni	yeni	PROPN
biomedich-761	127	9	aprillia	aprillia	PROPN
biomedich-761	127	10	,	,	PUNCT
biomedich-761	127	11	&	&	CCONJ
biomedich-761	127	12	nurul	nurul	PROPN
biomedich-761	127	13	apriani	apriani	PROPN
biomedich-761	127	14	designed	design	VERB
biomedich-761	127	15	the	the	DET
biomedich-761	127	16	study	study	NOUN
biomedich-761	127	17	.	.	PUNCT
biomedich-761	128	1	nurul	nurul	PROPN
biomedich-761	128	2	apriani	apriani	PROPN
biomedich-761	128	3	and	and	CCONJ
biomedich-761	128	4	winda	winda	PROPN
biomedich-761	128	5	trisna	trisna	PROPN
biomedich-761	128	6	wulandari	wulandari	PROPN
biomedich-761	128	7	carried	carry	VERB
biomedich-761	128	8	out	out	ADP
biomedich-761	128	9	the	the	DET
biomedich-761	128	10	laboratory	laboratory	NOUN
biomedich-761	128	11	work	work	NOUN
biomedich-761	128	12	.	.	PUNCT
biomedich-761	129	1	indra	indra	PROPN
biomedich-761	129	2	,	,	PUNCT
biomedich-761	129	3	gatut	gatut	PROPN
biomedich-761	129	4	ari	ari	PROPN
biomedich-761	129	5	wardani	wardani	PROPN
biomedich-761	129	6	&	&	CCONJ
biomedich-761	129	7	firman	firman	PROPN
biomedich-761	129	8	gustaman	gustaman	PROPN
biomedich-761	129	9	analyzed	analyze	VERB
biomedich-761	129	10	the	the	DET
biomedich-761	129	11	data	datum	NOUN
biomedich-761	129	12	.	.	PUNCT
biomedich-761	130	1	indra	indra	PROPN
biomedich-761	130	2	,	,	PUNCT
biomedich-761	130	3	nurul	nurul	NOUN
biomedich-761	130	4	apriani	apriani	PROPN
biomedich-761	130	5	,	,	PUNCT
biomedich-761	130	6	winda	winda	PROPN
biomedich-761	130	7	trisna	trisna	PROPN
biomedich-761	130	8	wulandari	wulandari	PROPN
biomedich-761	130	9	&	&	CCONJ
biomedich-761	130	10	firman	firman	PROPN
biomedich-761	130	11	gustaman	gustaman	PROPN
biomedich-761	130	12	wrote	write	VERB
biomedich-761	130	13	the	the	DET
biomedich-761	130	14	manuscript	manuscript	NOUN
biomedich-761	130	15	.	.	PUNCT
biomedich-761	131	1	all	all	DET
biomedich-761	131	2	authors	author	NOUN
biomedich-761	131	3	read	read	VERB
biomedich-761	131	4	and	and	CCONJ
biomedich-761	131	5	approved	approve	VERB
biomedich-761	131	6	the	the	DET
biomedich-761	131	7	final	final	ADJ
biomedich-761	131	8	version	version	NOUN
biomedich-761	131	9	of	of	ADP
biomedich-761	131	10	the	the	DET
biomedich-761	131	11	manuscript	manuscript	NOUN
biomedich-761	131	12	.	.	PUNCT
biomedich-761	132	1	competing	compete	VERB
biomedich-761	132	2	interests	interest	NOUN
biomedich-761	132	3	:	:	PUNCT
biomedich-761	132	4	the	the	DET
biomedich-761	132	5	authors	author	NOUN
biomedich-761	132	6	declare	declare	VERB
biomedich-761	132	7	that	that	SCONJ
biomedich-761	132	8	there	there	PRON
biomedich-761	132	9	are	be	VERB
biomedich-761	132	10	no	no	DET
biomedich-761	132	11	competing	compete	VERB
biomedich-761	132	12	interests	interest	NOUN
biomedich-761	132	13	.	.	PUNCT
biomedich-761	133	1	funding	funding	NOUN
biomedich-761	133	2	:	:	PUNCT
biomedich-761	133	3	this	this	DET
biomedich-761	133	4	research	research	NOUN
biomedich-761	133	5	received	receive	VERB
biomedich-761	133	6	no	no	DET
biomedich-761	133	7	external	external	ADJ
biomedich-761	133	8	funding	funding	NOUN
biomedich-761	133	9	.	.	PUNCT
biomedich-761	134	1	references	reference	NOUN
biomedich-761	134	2	alatas	alata	NOUN
biomedich-761	134	3	,	,	PUNCT
biomedich-761	134	4	f.	f.	PROPN
biomedich-761	134	5	,	,	PUNCT
biomedich-761	134	6	suwartiningsih	suwartiningsih	PROPN
biomedich-761	134	7	,	,	PUNCT
biomedich-761	134	8	n.	n.	NOUN
biomedich-761	134	9	,	,	PUNCT
biomedich-761	134	10	ratih	ratih	PROPN
biomedich-761	134	11	,	,	PUNCT
biomedich-761	134	12	h.	h.	PROPN
biomedich-761	134	13	,	,	PUNCT
biomedich-761	134	14	&	&	CCONJ
biomedich-761	134	15	sutarna	sutarna	PROPN
biomedich-761	134	16	,	,	PUNCT
biomedich-761	134	17	t.	t.	PROPN
biomedich-761	134	18	h.	h.	PROPN
biomedich-761	134	19	(	(	PUNCT
biomedich-761	134	20	2021	2021	NUM
biomedich-761	134	21	)	)	PUNCT
biomedich-761	134	22	.	.	PUNCT
biomedich-761	135	1	fluconazole	fluconazole	NOUN
biomedich-761	135	2	-	-	PUNCT
biomedich-761	135	3	tartaric	tartaric	NOUN
biomedich-761	135	4	acid	acid	NOUN
biomedich-761	135	5	co	co	NOUN
biomedich-761	135	6	-	-	NOUN
biomedich-761	135	7	crystal	crystal	ADJ
biomedich-761	135	8	formation	formation	NOUN
biomedich-761	135	9	and	and	CCONJ
biomedich-761	135	10	its	its	PRON
biomedich-761	135	11	mechanical	mechanical	ADJ
biomedich-761	135	12	properties	property	NOUN
biomedich-761	135	13	.	.	PUNCT
biomedich-761	136	1	pharmacy	pharmacy	NOUN
biomedich-761	136	2	education	education	NOUN
biomedich-761	136	3	,	,	PUNCT
biomedich-761	136	4	21(2	21(2	NUM
biomedich-761	136	5	)	)	PUNCT
biomedich-761	136	6	,	,	PUNCT
biomedich-761	136	7	116–122	116–122	NUM
biomedich-761	136	8	.	.	PUNCT
biomedich-761	137	1	https://doi.org/10.46542/pe.2021.212.116122	https://doi.org/10.46542/pe.2021.212.116122	NOUN
biomedich-761	137	2	babu	babu	PROPN
biomedich-761	137	3	,	,	PUNCT
biomedich-761	137	4	n.	n.	PROPN
biomedich-761	137	5	j.	j.	PROPN
biomedich-761	137	6	,	,	PUNCT
biomedich-761	137	7	&	&	CCONJ
biomedich-761	137	8	nangia	nangia	PROPN
biomedich-761	137	9	,	,	PUNCT
biomedich-761	137	10	a.	a.	NOUN
biomedich-761	137	11	(	(	PUNCT
biomedich-761	137	12	2011	2011	NUM
biomedich-761	137	13	)	)	PUNCT
biomedich-761	137	14	.	.	PUNCT
biomedich-761	138	1	solubility	solubility	NOUN
biomedich-761	138	2	advantage	advantage	NOUN
biomedich-761	138	3	of	of	ADP
biomedich-761	138	4	amorphous	amorphous	ADJ
biomedich-761	138	5	drugs	drug	NOUN
biomedich-761	138	6	and	and	CCONJ
biomedich-761	138	7	pharmaceutical	pharmaceutical	NOUN
biomedich-761	138	8	cocrystals	cocrystal	NOUN
biomedich-761	138	9	.	.	PUNCT
biomedich-761	139	1	crystal	crystal	NOUN
biomedich-761	139	2	growth	growth	PROPN
biomedich-761	139	3	&	&	CCONJ
biomedich-761	139	4	design	design	PROPN
biomedich-761	139	5	,	,	PUNCT
biomedich-761	139	6	11(7	11(7	NUM
biomedich-761	139	7	)	)	PUNCT
biomedich-761	139	8	,	,	PUNCT
biomedich-761	139	9	2662–2679	2662–2679	NUM
biomedich-761	139	10	.	.	PUNCT
biomedich-761	139	11	https://doi.org/10.1021/cg200492w	https://doi.org/10.1021/cg200492w	PROPN
biomedich-761	140	1	baghel	baghel	PROPN
biomedich-761	140	2	,	,	PUNCT
biomedich-761	140	3	s.	s.	PROPN
biomedich-761	140	4	,	,	PUNCT
biomedich-761	140	5	cathcart	cathcart	PROPN
biomedich-761	140	6	,	,	PUNCT
biomedich-761	140	7	h.	h.	PROPN
biomedich-761	140	8	,	,	PUNCT
biomedich-761	140	9	&	&	CCONJ
biomedich-761	140	10	o’reilly	o’reilly	ADV
biomedich-761	140	11	,	,	PUNCT
biomedich-761	140	12	n.	n.	PROPN
biomedich-761	140	13	j.	j.	PROPN
biomedich-761	140	14	(	(	PUNCT
biomedich-761	140	15	2016	2016	NUM
biomedich-761	140	16	)	)	PUNCT
biomedich-761	140	17	.	.	PUNCT
biomedich-761	141	1	polymeric	polymeric	ADJ
biomedich-761	141	2	amorphous	amorphous	ADJ
biomedich-761	141	3	solid	solid	ADJ
biomedich-761	141	4	dispersions	dispersion	NOUN
biomedich-761	141	5	:	:	PUNCT
biomedich-761	141	6	a	a	DET
biomedich-761	141	7	review	review	NOUN
biomedich-761	141	8	of	of	ADP
biomedich-761	141	9	amorphization	amorphization	NOUN
biomedich-761	141	10	,	,	PUNCT
biomedich-761	141	11	crystallization	crystallization	NOUN
biomedich-761	141	12	,	,	PUNCT
biomedich-761	141	13	stabilization	stabilization	NOUN
biomedich-761	141	14	,	,	PUNCT
biomedich-761	141	15	solid	solid	ADJ
biomedich-761	141	16	-	-	PUNCT
biomedich-761	141	17	state	state	NOUN
biomedich-761	141	18	characterization	characterization	NOUN
biomedich-761	141	19	,	,	PUNCT
biomedich-761	141	20	and	and	CCONJ
biomedich-761	141	21	aqueous	aqueous	ADJ
biomedich-761	141	22	solubilization	solubilization	NOUN
biomedich-761	141	23	of	of	ADP
biomedich-761	141	24	biopharmaceutical	biopharmaceutical	ADJ
biomedich-761	141	25	classification	classification	NOUN
biomedich-761	141	26	system	system	NOUN
biomedich-761	141	27	class	class	NOUN
biomedich-761	141	28	ii	ii	NOUN
biomedich-761	141	29	drugs	drug	NOUN
biomedich-761	141	30	.	.	PUNCT
biomedich-761	142	1	journal	journal	NOUN
biomedich-761	142	2	of	of	ADP
biomedich-761	142	3	pharmaceutical	pharmaceutical	NOUN
biomedich-761	142	4	sciences	science	NOUN
biomedich-761	142	5	,	,	PUNCT
biomedich-761	142	6	105(9	105(9	NUM
biomedich-761	142	7	)	)	PUNCT
biomedich-761	142	8	,	,	PUNCT
biomedich-761	142	9	2527–2544	2527–2544	NUM
biomedich-761	142	10	.	.	PUNCT
biomedich-761	142	11	https://doi.org/10.1016/j.xphs.2015.10.008	https://doi.org/10.1016/j.xphs.2015.10.008	PROPN
biomedich-761	142	12	chauhan	chauhan	PROPN
biomedich-761	142	13	,	,	PUNCT
biomedich-761	142	14	b.	b.	PROPN
biomedich-761	142	15	,	,	PUNCT
biomedich-761	142	16	shimpi	shimpi	PROPN
biomedich-761	142	17	,	,	PUNCT
biomedich-761	142	18	s.	s.	PROPN
biomedich-761	142	19	,	,	PUNCT
biomedich-761	142	20	&	&	CCONJ
biomedich-761	142	21	paradkar	paradkar	PROPN
biomedich-761	142	22	,	,	PUNCT
biomedich-761	142	23	a.	a.	NOUN
biomedich-761	142	24	(	(	PUNCT
biomedich-761	142	25	2005	2005	NUM
biomedich-761	142	26	)	)	PUNCT
biomedich-761	142	27	.	.	PUNCT
biomedich-761	143	1	preparation	preparation	NOUN
biomedich-761	143	2	and	and	CCONJ
biomedich-761	143	3	characterization	characterization	NOUN
biomedich-761	143	4	of	of	ADP
biomedich-761	143	5	etoricoxib	etoricoxib	ADJ
biomedich-761	143	6	solid	solid	ADJ
biomedich-761	143	7	dispersions	dispersion	NOUN
biomedich-761	143	8	using	use	VERB
biomedich-761	143	9	lipid	lipid	NOUN
biomedich-761	143	10	carriers	carrier	NOUN
biomedich-761	143	11	by	by	ADP
biomedich-761	143	12	spray	spray	NOUN
biomedich-761	143	13	drying	dry	VERB
biomedich-761	143	14	technique	technique	NOUN
biomedich-761	143	15	.	.	PUNCT
biomedich-761	144	1	aaps	aap	NOUN
biomedich-761	144	2	pharmscitech	pharmscitech	VERB
biomedich-761	144	3	,	,	PUNCT
biomedich-761	144	4	6(3	6(3	NUM
biomedich-761	144	5	)	)	PUNCT
biomedich-761	144	6	,	,	PUNCT
biomedich-761	144	7	e405	e405	PROPN
biomedich-761	144	8	–	–	PUNCT
biomedich-761	144	9	e409	e409	PROPN
biomedich-761	144	10	.	.	PUNCT
biomedich-761	144	11	https://doi.org/10.1208/pt060350	https://doi.org/10.1208/pt060350	PROPN
biomedich-761	145	1	doshi	doshi	PROPN
biomedich-761	145	2	,	,	PUNCT
biomedich-761	145	3	m.	m.	NOUN
biomedich-761	145	4	,	,	PUNCT
biomedich-761	145	5	kakade	kakade	NOUN
biomedich-761	145	6	,	,	PUNCT
biomedich-761	145	7	p.	p.	PROPN
biomedich-761	145	8	,	,	PUNCT
biomedich-761	145	9	.	.	PUNCT
biomedich-761	146	1	t.	t.	PROPN
biomedich-761	146	2	d.	d.	PROPN
biomedich-761	146	3	,	,	PUNCT
biomedich-761	146	4	gandhi	gandhi	PROPN
biomedich-761	146	5	,	,	PUNCT
biomedich-761	146	6	r.	r.	PROPN
biomedich-761	146	7	p.	p.	PROPN
biomedich-761	146	8	,	,	PUNCT
biomedich-761	146	9	&	&	CCONJ
biomedich-761	146	10	mali	mali	PROPN
biomedich-761	146	11	,	,	PUNCT
biomedich-761	146	12	k.	k.	PROPN
biomedich-761	146	13	k.	k.	PROPN
biomedich-761	146	14	(	(	PUNCT
biomedich-761	146	15	2024	2024	NUM
biomedich-761	146	16	)	)	PUNCT
biomedich-761	146	17	.	.	PUNCT
biomedich-761	147	1	ketoprofen	ketoprofen	VERB
biomedich-761	147	2	loaded	load	VERB
biomedich-761	147	3	β	β	NOUN
biomedich-761	147	4	-	-	ADJ
biomedich-761	147	5	cyclodextrin	cyclodextrin	NOUN
biomedich-761	147	6	complexation	complexation	NOUN
biomedich-761	147	7	for	for	ADP
biomedich-761	147	8	enhancing	enhance	VERB
biomedich-761	147	9	solubility	solubility	NOUN
biomedich-761	147	10	of	of	ADP
biomedich-761	147	11	bcs	bcs	NOUN
biomedich-761	147	12	class	class	NOUN
biomedich-761	147	13	ii	ii	NOUN
biomedich-761	147	14	drugs	drug	NOUN
biomedich-761	147	15	.	.	PUNCT
biomedich-761	148	1	https://doi.org/10.21203/rs.3.rs-5315469/v1	https://doi.org/10.21203/rs.3.rs-5315469/v1	PROPN
biomedich-761	149	1	fan	fan	PROPN
biomedich-761	149	2	,	,	PUNCT
biomedich-761	149	3	w.	w.	PROPN
biomedich-761	149	4	,	,	PUNCT
biomedich-761	149	5	zhu	zhu	PROPN
biomedich-761	149	6	,	,	PUNCT
biomedich-761	149	7	w.	w.	PROPN
biomedich-761	149	8	,	,	PUNCT
biomedich-761	149	9	zhang	zhang	PROPN
biomedich-761	149	10	,	,	PUNCT
biomedich-761	149	11	x.	x.	PROPN
biomedich-761	149	12	,	,	PUNCT
biomedich-761	149	13	xu	xu	PROPN
biomedich-761	149	14	,	,	PUNCT
biomedich-761	149	15	y.	y.	PROPN
biomedich-761	149	16	,	,	PUNCT
biomedich-761	149	17	&	&	CCONJ
biomedich-761	149	18	di	di	PROPN
biomedich-761	149	19	,	,	PUNCT
biomedich-761	149	20	l.	l.	PROPN
biomedich-761	149	21	(	(	PUNCT
biomedich-761	149	22	2019	2019	NUM
biomedich-761	149	23	)	)	PUNCT
biomedich-761	149	24	.	.	PUNCT
biomedich-761	150	1	application	application	NOUN
biomedich-761	150	2	of	of	ADP
biomedich-761	150	3	the	the	DET
biomedich-761	150	4	combination	combination	NOUN
biomedich-761	150	5	of	of	ADP
biomedich-761	150	6	ball	ball	NOUN
biomedich-761	150	7	-	-	PUNCT
biomedich-761	150	8	milling	milling	NOUN
biomedich-761	150	9	and	and	CCONJ
biomedich-761	150	10	hot	hot	ADJ
biomedich-761	150	11	-	-	PUNCT
biomedich-761	150	12	melt	melt	NOUN
biomedich-761	150	13	extrusion	extrusion	NOUN
biomedich-761	150	14	in	in	ADP
biomedich-761	150	15	the	the	DET
biomedich-761	150	16	development	development	NOUN
biomedich-761	150	17	of	of	ADP
biomedich-761	150	18	an	an	DET
biomedich-761	150	19	amorphous	amorphous	ADJ
biomedich-761	150	20	solid	solid	ADJ
biomedich-761	150	21	dispersion	dispersion	NOUN
biomedich-761	150	22	of	of	ADP
biomedich-761	150	23	a	a	DET
biomedich-761	150	24	poorly	poorly	ADV
biomedich-761	150	25	water	water	NOUN
biomedich-761	150	26	-	-	PUNCT
biomedich-761	150	27	soluble	soluble	ADJ
biomedich-761	150	28	drug	drug	NOUN
biomedich-761	150	29	with	with	ADP
biomedich-761	150	30	high	high	ADJ
biomedich-761	150	31	melting	melting	NOUN
biomedich-761	150	32	point	point	NOUN
biomedich-761	150	33	.	.	PUNCT
biomedich-761	151	1	rsc	rsc	PROPN
biomedich-761	151	2	advances	advance	NOUN
biomedich-761	151	3	,	,	PUNCT
biomedich-761	151	4	9(39	9(39	NUM
biomedich-761	151	5	)	)	PUNCT
biomedich-761	151	6	,	,	PUNCT
biomedich-761	151	7	22263–22273	22263–22273	NUM
biomedich-761	151	8	.	.	PUNCT
biomedich-761	152	1	https://doi.org/10.1039/c9ra00810a	https://doi.org/10.1039/c9ra00810a	PROPN
biomedich-761	152	2	fine‐shamir	fine‐shamir	NOUN
biomedich-761	152	3	,	,	PUNCT
biomedich-761	152	4	n.	n.	NOUN
biomedich-761	152	5	,	,	PUNCT
biomedich-761	152	6	&	&	CCONJ
biomedich-761	152	7	dahan	dahan	PROPN
biomedich-761	152	8	,	,	PUNCT
biomedich-761	152	9	a.	a.	NOUN
biomedich-761	152	10	(	(	PUNCT
biomedich-761	152	11	2019	2019	NUM
biomedich-761	152	12	)	)	PUNCT
biomedich-761	152	13	.	.	PUNCT
biomedich-761	153	1	methacrylate	methacrylate	NOUN
biomedich-761	153	2	-	-	PUNCT
biomedich-761	153	3	copolymer	copolymer	NOUN
biomedich-761	153	4	eudragit	eudragit	NOUN
biomedich-761	153	5	epo	epo	PROPN
biomedich-761	153	6	as	as	ADP
biomedich-761	153	7	a	a	DET
biomedich-761	153	8	solubility	solubility	NOUN
biomedich-761	153	9	-	-	PUNCT
biomedich-761	153	10	enabling	enable	VERB
biomedich-761	153	11	excipient	excipient	NOUN
biomedich-761	153	12	for	for	ADP
biomedich-761	153	13	anionic	anionic	ADJ
biomedich-761	153	14	drugs	drug	NOUN
biomedich-761	153	15	:	:	PUNCT
biomedich-761	153	16	investigation	investigation	NOUN
biomedich-761	153	17	of	of	ADP
biomedich-761	153	18	drug	drug	NOUN
biomedich-761	153	19	solubility	solubility	NOUN
biomedich-761	153	20	,	,	PUNCT
biomedich-761	153	21	intestinal	intestinal	ADJ
biomedich-761	153	22	permeability	permeability	NOUN
biomedich-761	153	23	,	,	PUNCT
biomedich-761	153	24	and	and	CCONJ
biomedich-761	153	25	their	their	PRON
biomedich-761	153	26	interplay	interplay	NOUN
biomedich-761	153	27	.	.	PUNCT
biomedich-761	154	1	molecular	molecular	ADJ
biomedich-761	154	2	pharmaceutics	pharmaceutic	NOUN
biomedich-761	154	3	,	,	PUNCT
biomedich-761	154	4	16(7	16(7	NUM
biomedich-761	154	5	)	)	PUNCT
biomedich-761	154	6	,	,	PUNCT
biomedich-761	154	7	2884–2891	2884–2891	NUM
biomedich-761	154	8	.	.	PUNCT
biomedich-761	154	9	https://doi.org/10.1021/acs.molpharmaceut.9b00057	https://doi.org/10.1021/acs.molpharmaceut.9b00057	PROPN
biomedich-761	154	10	fitriani	fitriani	PROPN
biomedich-761	154	11	,	,	PUNCT
biomedich-761	154	12	l.	l.	PROPN
biomedich-761	154	13	,	,	PUNCT
biomedich-761	154	14	ramadhani	ramadhani	PROPN
biomedich-761	154	15	,	,	PUNCT
biomedich-761	154	16	s.	s.	PROPN
biomedich-761	154	17	,	,	PUNCT
biomedich-761	154	18	&	&	CCONJ
biomedich-761	154	19	zaini	zaini	PROPN
biomedich-761	154	20	,	,	PUNCT
biomedich-761	154	21	e.	e.	PROPN
biomedich-761	154	22	(	(	PUNCT
biomedich-761	154	23	2017	2017	NUM
biomedich-761	154	24	)	)	PUNCT
biomedich-761	154	25	.	.	PUNCT
biomedich-761	155	1	preparation	preparation	NOUN
biomedich-761	155	2	and	and	CCONJ
biomedich-761	155	3	characterization	characterization	NOUN
biomedich-761	155	4	of	of	ADP
biomedich-761	155	5	solid	solid	ADJ
biomedich-761	155	6	dispersion	dispersion	NOUN
biomedich-761	155	7	famotidine	famotidine	NOUN
biomedich-761	155	8	–	–	PUNCT
biomedich-761	155	9	mannitol	mannitol	NOUN
biomedich-761	155	10	by	by	ADP
biomedich-761	155	11	co	co	VERB
biomedich-761	155	12	-	-	ADJ
biomedich-761	155	13	grinding	grinding	ADJ
biomedich-761	155	14	method	method	NOUN
biomedich-761	155	15	.	.	PUNCT
biomedich-761	156	1	asian	asian	ADJ
biomedich-761	156	2	journal	journal	PROPN
biomedich-761	156	3	of	of	ADP
biomedich-761	156	4	pharmaceutical	pharmaceutical	NOUN
biomedich-761	156	5	and	and	CCONJ
biomedich-761	156	6	clinical	clinical	ADJ
biomedich-761	156	7	research	research	NOUN
biomedich-761	156	8	,	,	PUNCT
biomedich-761	156	9	10(3	10(3	NUM
biomedich-761	156	10	)	)	PUNCT
biomedich-761	156	11	,	,	PUNCT
biomedich-761	156	12	249	249	NUM
biomedich-761	156	13	.	.	PUNCT
biomedich-761	157	1	https://doi.org/10.22159/ajpcr.2017.v10i3.16112	https://doi.org/10.22159/ajpcr.2017.v10i3.16112	PROPN
biomedich-761	157	2	fontana	fontana	PROPN
biomedich-761	157	3	,	,	PUNCT
biomedich-761	157	4	f.	f.	PROPN
biomedich-761	157	5	,	,	PUNCT
biomedich-761	157	6	figueiredo	figueiredo	PROPN
biomedich-761	157	7	,	,	PUNCT
biomedich-761	157	8	p.	p.	PROPN
biomedich-761	157	9	,	,	PUNCT
biomedich-761	157	10	zhang	zhang	PROPN
biomedich-761	157	11	,	,	PUNCT
biomedich-761	157	12	p.	p.	PROPN
biomedich-761	157	13	,	,	PUNCT
biomedich-761	157	14	hirvonen	hirvonen	PROPN
biomedich-761	157	15	,	,	PUNCT
biomedich-761	157	16	j.	j.	PROPN
biomedich-761	157	17	,	,	PUNCT
biomedich-761	157	18	liu	liu	PROPN
biomedich-761	157	19	,	,	PUNCT
biomedich-761	157	20	d.	d.	PROPN
biomedich-761	157	21	,	,	PUNCT
biomedich-761	157	22	&	&	CCONJ
biomedich-761	157	23	santos	santos	PROPN
biomedich-761	157	24	,	,	PUNCT
biomedich-761	157	25	h.	h.	PROPN
biomedich-761	157	26	a.	a.	PROPN
biomedich-761	157	27	(	(	PUNCT
biomedich-761	157	28	2018	2018	NUM
biomedich-761	157	29	)	)	PUNCT
biomedich-761	157	30	.	.	PUNCT
biomedich-761	158	1	production	production	NOUN
biomedich-761	158	2	of	of	ADP
biomedich-761	158	3	pure	pure	ADJ
biomedich-761	158	4	drug	drug	NOUN
biomedich-761	158	5	nanocrystals	nanocrystal	NOUN
biomedich-761	158	6	and	and	CCONJ
biomedich-761	158	7	nano	nano	NOUN
biomedich-761	158	8	co	co	NOUN
biomedich-761	158	9	-	-	NOUN
biomedich-761	158	10	crystals	crystal	NOUN
biomedich-761	158	11	by	by	ADP
biomedich-761	158	12	confinement	confinement	ADJ
biomedich-761	158	13	methods	method	NOUN
biomedich-761	158	14	.	.	PUNCT
biomedich-761	159	1	advanced	advanced	ADJ
biomedich-761	159	2	drug	drug	NOUN
biomedich-761	159	3	delivery	delivery	NOUN
biomedich-761	159	4	reviews	review	NOUN
biomedich-761	159	5	,	,	PUNCT
biomedich-761	159	6	131	131	NUM
biomedich-761	159	7	,	,	PUNCT
biomedich-761	159	8	3–21	3–21	NOUN
biomedich-761	159	9	.	.	PUNCT
biomedich-761	160	1	https://doi.org/10.1016/j.addr.2018.05.002	https://doi.org/10.1016/j.addr.2018.05.002	PROPN
biomedich-761	160	2	garbiec	garbiec	NOUN
biomedich-761	160	3	,	,	PUNCT
biomedich-761	160	4	e.	e.	PROPN
biomedich-761	160	5	,	,	PUNCT
biomedich-761	160	6	rosiak	rosiak	PROPN
biomedich-761	160	7	,	,	PUNCT
biomedich-761	160	8	n.	n.	NOUN
biomedich-761	160	9	,	,	PUNCT
biomedich-761	160	10	zalewski	zalewski	NOUN
biomedich-761	160	11	,	,	PUNCT
biomedich-761	160	12	p.	p.	NOUN
biomedich-761	160	13	,	,	PUNCT
biomedich-761	160	14	tajber	tajber	PROPN
biomedich-761	160	15	,	,	PUNCT
biomedich-761	160	16	l.	l.	PROPN
biomedich-761	160	17	,	,	PUNCT
biomedich-761	160	18	&	&	CCONJ
biomedich-761	160	19	cielecka‐piontek	cielecka‐piontek	PROPN
biomedich-761	160	20	,	,	PUNCT
biomedich-761	160	21	j.	j.	PROPN
biomedich-761	160	22	(	(	PUNCT
biomedich-761	160	23	2023	2023	NUM
biomedich-761	160	24	)	)	PUNCT
biomedich-761	160	25	.	.	PUNCT
biomedich-761	161	1	genistein	genistein	PROPN
biomedich-761	161	2	co	co	ADJ
biomedich-761	161	3	-	-	ADJ
biomedich-761	161	4	amorphous	amorphous	ADJ
biomedich-761	161	5	systems	system	NOUN
biomedich-761	161	6	606	606	NUM
biomedich-761	161	7	biology	biology	NOUN
biomedich-761	161	8	,	,	PUNCT
biomedich-761	161	9	medicine	medicine	NOUN
biomedich-761	161	10	,	,	PUNCT
biomedich-761	161	11	&	&	CCONJ
biomedich-761	161	12	natural	natural	ADJ
biomedich-761	161	13	product	product	NOUN
biomedich-761	161	14	chemistry	chemistry	NOUN
biomedich-761	161	15	14	14	NUM
biomedich-761	161	16	(	(	PUNCT
biomedich-761	161	17	2	2	NUM
biomedich-761	161	18	)	)	PUNCT
biomedich-761	161	19	,	,	PUNCT
biomedich-761	161	20	2025	2025	NUM
biomedich-761	161	21	:	:	PUNCT
biomedich-761	161	22	601	601	NUM
biomedich-761	161	23	-	-	NUM
biomedich-761	161	24	607	607	NUM
biomedich-761	161	25	with	with	ADP
biomedich-761	161	26	amino	amino	ADJ
biomedich-761	161	27	acids	acid	NOUN
biomedich-761	161	28	:	:	PUNCT
biomedich-761	161	29	an	an	DET
biomedich-761	161	30	investigation	investigation	NOUN
biomedich-761	161	31	into	into	ADP
biomedich-761	161	32	enhanced	enhanced	ADJ
biomedich-761	161	33	solubility	solubility	NOUN
biomedich-761	161	34	and	and	CCONJ
biomedich-761	161	35	biological	biological	ADJ
biomedich-761	161	36	activity	activity	NOUN
biomedich-761	161	37	.	.	PUNCT
biomedich-761	162	1	pharmaceutics	pharmaceutic	NOUN
biomedich-761	162	2	,	,	PUNCT
biomedich-761	162	3	15(12	15(12	NUM
biomedich-761	162	4	)	)	PUNCT
biomedich-761	162	5	,	,	PUNCT
biomedich-761	162	6	2653	2653	NUM
biomedich-761	162	7	.	.	PUNCT
biomedich-761	163	1	https://doi.org/10.3390/pharmaceutics15122653	https://doi.org/10.3390/pharmaceutics15122653	PROPN
biomedich-761	163	2	ghyadh	ghyadh	PROPN
biomedich-761	163	3	,	,	PUNCT
biomedich-761	163	4	b.	b.	PROPN
biomedich-761	163	5	k.	k.	PROPN
biomedich-761	163	6	k.	k.	PROPN
biomedich-761	163	7	,	,	PUNCT
biomedich-761	163	8	&	&	CCONJ
biomedich-761	163	9	al	al	PROPN
biomedich-761	163	10	-	-	PUNCT
biomedich-761	163	11	khedairy	khedairy	PROPN
biomedich-761	163	12	,	,	PUNCT
biomedich-761	163	13	e.	e.	PROPN
biomedich-761	163	14	b.	b.	PROPN
biomedich-761	163	15	h.	h.	PROPN
biomedich-761	163	16	(	(	PUNCT
biomedich-761	163	17	2023	2023	NUM
biomedich-761	163	18	)	)	PUNCT
biomedich-761	163	19	.	.	PUNCT
biomedich-761	164	1	solubility	solubility	NOUN
biomedich-761	164	2	and	and	CCONJ
biomedich-761	164	3	dissolution	dissolution	NOUN
biomedich-761	164	4	enhancement	enhancement	NOUN
biomedich-761	164	5	of	of	ADP
biomedich-761	164	6	atorvastatin	atorvastatin	PROPN
biomedich-761	164	7	calcium	calcium	NOUN
biomedich-761	164	8	using	use	VERB
biomedich-761	164	9	phospholipid	phospholipid	NOUN
biomedich-761	164	10	solid	solid	ADJ
biomedich-761	164	11	dispersion	dispersion	NOUN
biomedich-761	164	12	technique	technique	NOUN
biomedich-761	164	13	.	.	PUNCT
biomedich-761	165	1	iraqi	iraqi	ADJ
biomedich-761	165	2	journal	journal	PROPN
biomedich-761	165	3	of	of	ADP
biomedich-761	165	4	pharmaceutical	pharmaceutical	ADJ
biomedich-761	165	5	sciences	science	NOUN
biomedich-761	165	6	(	(	PUNCT
biomedich-761	165	7	p	p	PROPN
biomedich-761	165	8	-	-	PUNCT
biomedich-761	165	9	issn	issn	VERB
biomedich-761	165	10	1683	1683	NUM
biomedich-761	165	11	3597	3597	NUM
biomedich-761	165	12	e	e	NOUN
biomedich-761	165	13	-	-	NOUN
biomedich-761	165	14	issn	issn	VERB
biomedich-761	165	15	2521	2521	NUM
biomedich-761	165	16	3512	3512	NUM
biomedich-761	165	17	)	)	PUNCT
biomedich-761	165	18	,	,	PUNCT
biomedich-761	165	19	32(suppl	32(suppl	NUM
biomedich-761	165	20	.	.	NUM
biomedich-761	165	21	)	)	PUNCT
biomedich-761	165	22	,	,	PUNCT
biomedich-761	165	23	244–253	244–253	NUM
biomedich-761	165	24	.	.	PUNCT
biomedich-761	166	1	https://doi.org/10.31351/vol32isssuppl.pp244-253	https://doi.org/10.31351/vol32isssuppl.pp244-253	PROPN
biomedich-761	166	2	guedes	guedes	PROPN
biomedich-761	166	3	,	,	PUNCT
biomedich-761	166	4	f.	f.	PROPN
biomedich-761	166	5	l.	l.	PROPN
biomedich-761	166	6	,	,	PUNCT
biomedich-761	166	7	oliveira	oliveira	PROPN
biomedich-761	166	8	,	,	PUNCT
biomedich-761	166	9	b.	b.	PROPN
biomedich-761	166	10	g.	g.	PROPN
biomedich-761	166	11	,	,	PUNCT
biomedich-761	166	12	hernandes	hernandes	PROPN
biomedich-761	166	13	,	,	PUNCT
biomedich-761	166	14	m.	m.	PROPN
biomedich-761	166	15	z.	z.	PROPN
biomedich-761	166	16	,	,	PUNCT
biomedich-761	166	17	simone	simone	PROPN
biomedich-761	166	18	,	,	PUNCT
biomedich-761	166	19	c.	c.	PROPN
biomedich-761	166	20	a.	a.	PROPN
biomedich-761	166	21	d.	d.	PROPN
biomedich-761	166	22	,	,	PUNCT
biomedich-761	166	23	veiga	veiga	PROPN
biomedich-761	166	24	,	,	PUNCT
biomedich-761	166	25	f.	f.	PROPN
biomedich-761	166	26	,	,	PUNCT
biomedich-761	166	27	lima	lima	PROPN
biomedich-761	166	28	,	,	PUNCT
biomedich-761	166	29	m.	m.	NOUN
biomedich-761	166	30	do	do	VERB
biomedich-761	166	31	c.	c.	PROPN
biomedich-761	166	32	a.	a.	PROPN
biomedich-761	166	33	de	de	PROPN
biomedich-761	166	34	,	,	PUNCT
biomedich-761	166	35	pitta	pitta	NOUN
biomedich-761	166	36	,	,	PUNCT
biomedich-761	166	37	i.	i.	PROPN
biomedich-761	166	38	d.	d.	PROPN
biomedich-761	166	39	r.	r.	PROPN
biomedich-761	166	40	,	,	PUNCT
biomedich-761	166	41	galdino	galdino	PROPN
biomedich-761	166	42	,	,	PUNCT
biomedich-761	166	43	s.	s.	PROPN
biomedich-761	166	44	l.	l.	PROPN
biomedich-761	166	45	,	,	PUNCT
biomedich-761	166	46	&	&	CCONJ
biomedich-761	166	47	neto	neto	PROPN
biomedich-761	166	48	,	,	PUNCT
biomedich-761	166	49	p.	p.	PROPN
biomedich-761	166	50	j.	j.	PROPN
biomedich-761	166	51	r.	r.	PROPN
biomedich-761	166	52	(	(	PUNCT
biomedich-761	166	53	2011	2011	NUM
biomedich-761	166	54	)	)	PUNCT
biomedich-761	166	55	.	.	PUNCT
biomedich-761	167	1	solid	solid	ADJ
biomedich-761	167	2	dispersions	dispersion	NOUN
biomedich-761	167	3	of	of	ADP
biomedich-761	167	4	imidazolidinedione	imidazolidinedione	NOUN
biomedich-761	167	5	by	by	ADP
biomedich-761	167	6	peg	peg	NOUN
biomedich-761	167	7	and	and	CCONJ
biomedich-761	167	8	pvp	pvp	VERB
biomedich-761	167	9	polymers	polymer	NOUN
biomedich-761	167	10	with	with	ADP
biomedich-761	167	11	potential	potential	ADJ
biomedich-761	167	12	antischistosomal	antischistosomal	ADJ
biomedich-761	167	13	activities	activity	NOUN
biomedich-761	167	14	.	.	PUNCT
biomedich-761	168	1	aaps	aap	NOUN
biomedich-761	168	2	pharmscitech	pharmscitech	VERB
biomedich-761	168	3	,	,	PUNCT
biomedich-761	168	4	12(1	12(1	NUM
biomedich-761	168	5	)	)	PUNCT
biomedich-761	168	6	,	,	PUNCT
biomedich-761	168	7	401	401	NUM
biomedich-761	168	8	–	–	PUNCT
biomedich-761	168	9	410	410	NUM
biomedich-761	168	10	.	.	PUNCT
biomedich-761	169	1	https://doi.org/10.1208/s12249-010-9556-z	https://doi.org/10.1208/s12249-010-9556-z	PROPN
biomedich-761	169	2	kim	kim	PROPN
biomedich-761	169	3	,	,	PUNCT
biomedich-761	169	4	e.	e.	PROPN
biomedich-761	169	5	s.	s.	PROPN
biomedich-761	169	6	,	,	PUNCT
biomedich-761	169	7	chun	chun	PROPN
biomedich-761	169	8	,	,	PUNCT
biomedich-761	169	9	m.	m.	NOUN
biomedich-761	169	10	,	,	PUNCT
biomedich-761	169	11	jang	jang	PROPN
biomedich-761	169	12	,	,	PUNCT
biomedich-761	169	13	j.	j.	PROPN
biomedich-761	169	14	,	,	PUNCT
biomedich-761	169	15	lee	lee	PROPN
biomedich-761	169	16	,	,	PUNCT
biomedich-761	169	17	i.	i.	PROPN
biomedich-761	169	18	s.	s.	PROPN
biomedich-761	169	19	,	,	PUNCT
biomedich-761	169	20	lee	lee	PROPN
biomedich-761	169	21	,	,	PUNCT
biomedich-761	169	22	k.	k.	PROPN
biomedich-761	169	23	,	,	PUNCT
biomedich-761	169	24	&	&	CCONJ
biomedich-761	169	25	choi	choi	PROPN
biomedich-761	169	26	,	,	PUNCT
biomedich-761	169	27	h.	h.	PROPN
biomedich-761	169	28	(	(	PUNCT
biomedich-761	169	29	2006	2006	NUM
biomedich-761	169	30	)	)	PUNCT
biomedich-761	169	31	.	.	PUNCT
biomedich-761	170	1	preparation	preparation	NOUN
biomedich-761	170	2	of	of	ADP
biomedich-761	170	3	a	a	DET
biomedich-761	170	4	solid	solid	ADJ
biomedich-761	170	5	dispersion	dispersion	NOUN
biomedich-761	170	6	of	of	ADP
biomedich-761	170	7	felodipine	felodipine	NOUN
biomedich-761	170	8	using	use	VERB
biomedich-761	170	9	a	a	DET
biomedich-761	170	10	solvent	solvent	ADJ
biomedich-761	170	11	wetting	wetting	NOUN
biomedich-761	170	12	method	method	NOUN
biomedich-761	170	13	.	.	PUNCT
biomedich-761	171	1	european	european	PROPN
biomedich-761	171	2	journal	journal	PROPN
biomedich-761	171	3	of	of	ADP
biomedich-761	171	4	pharmaceutics	pharmaceutic	NOUN
biomedich-761	171	5	and	and	CCONJ
biomedich-761	171	6	biopharmaceutics	biopharmaceutic	NOUN
biomedich-761	171	7	,	,	PUNCT
biomedich-761	171	8	64(2	64(2	NUM
biomedich-761	171	9	)	)	PUNCT
biomedich-761	171	10	,	,	PUNCT
biomedich-761	171	11	200–205	200–205	NUM
biomedich-761	171	12	.	.	PUNCT
biomedich-761	172	1	https://doi.org/10.1016/j.ejpb.2006.04.001	https://doi.org/10.1016/j.ejpb.2006.04.001	PROPN
biomedich-761	172	2	kumar	kumar	PROPN
biomedich-761	172	3	,	,	PUNCT
biomedich-761	172	4	a.	a.	NOUN
biomedich-761	172	5	(	(	PUNCT
biomedich-761	172	6	2017	2017	NUM
biomedich-761	172	7	)	)	PUNCT
biomedich-761	172	8	.	.	PUNCT
biomedich-761	173	1	solid	solid	ADJ
biomedich-761	173	2	dispersionstrategy	dispersionstrategy	NOUN
biomedich-761	173	3	to	to	PART
biomedich-761	173	4	enhance	enhance	VERB
biomedich-761	173	5	solubility	solubility	NOUN
biomedich-761	173	6	and	and	CCONJ
biomedich-761	173	7	dissolution	dissolution	NOUN
biomedich-761	173	8	of	of	ADP
biomedich-761	173	9	poorly	poorly	ADV
biomedich-761	173	10	water	water	NOUN
biomedich-761	173	11	soluble	soluble	ADJ
biomedich-761	173	12	drugs	drug	NOUN
biomedich-761	173	13	.	.	PUNCT
biomedich-761	174	1	universal	universal	ADJ
biomedich-761	174	2	journal	journal	PROPN
biomedich-761	174	3	of	of	ADP
biomedich-761	174	4	pharmaceutical	pharmaceutical	NOUN
biomedich-761	174	5	research	research	NOUN
biomedich-761	174	6	,	,	PUNCT
biomedich-761	174	7	2(5	2(5	NUM
biomedich-761	174	8	)	)	PUNCT
biomedich-761	174	9	,	,	PUNCT
biomedich-761	174	10	54–59	54–59	NUM
biomedich-761	174	11	.	.	PUNCT
biomedich-761	175	1	https://doi.org/10.22270/ujpr.v2i5.rw4	https://doi.org/10.22270/ujpr.v2i5.rw4	PROPN
biomedich-761	175	2	kumar	kumar	PROPN
biomedich-761	175	3	,	,	PUNCT
biomedich-761	175	4	h.	h.	PROPN
biomedich-761	175	5	,	,	PUNCT
biomedich-761	175	6	kumar	kumar	PROPN
biomedich-761	175	7	,	,	PUNCT
biomedich-761	175	8	a.	a.	NOUN
biomedich-761	175	9	,	,	PUNCT
biomedich-761	175	10	rajpoot	rajpoot	NOUN
biomedich-761	175	11	,	,	PUNCT
biomedich-761	175	12	&	&	CCONJ
biomedich-761	175	13	sharma	sharma	PROPN
biomedich-761	175	14	,	,	PUNCT
biomedich-761	175	15	s.	s.	PROPN
biomedich-761	175	16	(	(	PUNCT
biomedich-761	175	17	2022	2022	NUM
biomedich-761	175	18	)	)	PUNCT
biomedich-761	175	19	.	.	PUNCT
biomedich-761	176	1	fabrication	fabrication	NOUN
biomedich-761	176	2	and	and	CCONJ
biomedich-761	176	3	characterization	characterization	NOUN
biomedich-761	176	4	of	of	ADP
biomedich-761	176	5	griseofulvin	griseofulvin	NOUN
biomedich-761	176	6	loaded	load	VERB
biomedich-761	176	7	solid	solid	ADJ
biomedich-761	176	8	lipid	lipid	NOUN
biomedich-761	176	9	nanoparticles	nanoparticle	NOUN
biomedich-761	176	10	for	for	ADP
biomedich-761	176	11	improved	improved	ADJ
biomedich-761	176	12	oral	oral	ADJ
biomedich-761	176	13	delivery	delivery	NOUN
biomedich-761	176	14	of	of	ADP
biomedich-761	176	15	bcs	bcs	NOUN
biomedich-761	176	16	class	class	PROPN
biomedich-761	176	17	ii	ii	PROPN
biomedich-761	176	18	drug	drug	NOUN
biomedich-761	176	19	.	.	PUNCT
biomedich-761	177	1	pnr	pnr	PROPN
biomedich-761	177	2	,	,	PUNCT
biomedich-761	177	3	13(s01	13(s01	NUM
biomedich-761	177	4	)	)	PUNCT
biomedich-761	177	5	.	.	PUNCT
biomedich-761	178	1	https://doi.org/10.47750/pnr.2022.13.s01.248	https://doi.org/10.47750/pnr.2022.13.s01.248	ADP
biomedich-761	178	2	liu	liu	PROPN
biomedich-761	178	3	,	,	PUNCT
biomedich-761	178	4	j.	j.	PROPN
biomedich-761	178	5	,	,	PUNCT
biomedich-761	178	6	zou	zou	PROPN
biomedich-761	178	7	,	,	PUNCT
biomedich-761	178	8	m.	m.	NOUN
biomedich-761	178	9	,	,	PUNCT
biomedich-761	178	10	piao	piao	NOUN
biomedich-761	178	11	,	,	PUNCT
biomedich-761	178	12	h.	h.	PROPN
biomedich-761	178	13	,	,	PUNCT
biomedich-761	178	14	liu	liu	PROPN
biomedich-761	178	15	,	,	PUNCT
biomedich-761	178	16	y.	y.	PROPN
biomedich-761	178	17	,	,	PUNCT
biomedich-761	178	18	tang	tang	PROPN
biomedich-761	178	19	,	,	PUNCT
biomedich-761	178	20	b.	b.	PROPN
biomedich-761	178	21	,	,	PUNCT
biomedich-761	178	22	gao	gao	PROPN
biomedich-761	178	23	,	,	PUNCT
biomedich-761	178	24	y.	y.	PROPN
biomedich-761	178	25	,	,	PUNCT
biomedich-761	178	26	ma	ma	PROPN
biomedich-761	178	27	,	,	PUNCT
biomedich-761	178	28	n.	n.	NOUN
biomedich-761	178	29	,	,	PUNCT
biomedich-761	178	30	&	&	CCONJ
biomedich-761	178	31	cheng	cheng	PROPN
biomedich-761	178	32	,	,	PUNCT
biomedich-761	178	33	g.	g.	PROPN
biomedich-761	178	34	(	(	PUNCT
biomedich-761	178	35	2015	2015	NUM
biomedich-761	178	36	)	)	PUNCT
biomedich-761	178	37	.	.	PUNCT
biomedich-761	179	1	characterization	characterization	NOUN
biomedich-761	179	2	and	and	CCONJ
biomedich-761	179	3	pharmacokinetic	pharmacokinetic	ADJ
biomedich-761	179	4	study	study	NOUN
biomedich-761	179	5	of	of	ADP
biomedich-761	179	6	aprepitant	aprepitant	ADJ
biomedich-761	179	7	solid	solid	ADJ
biomedich-761	179	8	dispersions	dispersion	NOUN
biomedich-761	179	9	with	with	ADP
biomedich-761	179	10	soluplus	soluplus	ADJ
biomedich-761	179	11	®	®	NOUN
biomedich-761	179	12	.	.	PUNCT
biomedich-761	180	1	molecules	molecule	NOUN
biomedich-761	180	2	,	,	PUNCT
biomedich-761	180	3	20(6	20(6	NOUN
biomedich-761	180	4	)	)	PUNCT
biomedich-761	180	5	,	,	PUNCT
biomedich-761	180	6	11345–11356	11345–11356	NUM
biomedich-761	180	7	.	.	PUNCT
biomedich-761	181	1	https://doi.org/10.3390/molecules200611345	https://doi.org/10.3390/molecules200611345	PROPN
biomedich-761	181	2	mardiyanto	mardiyanto	PROPN
biomedich-761	181	3	,	,	PUNCT
biomedich-761	181	4	m.	m.	NOUN
biomedich-761	181	5	,	,	PUNCT
biomedich-761	181	6	untari	untari	PROPN
biomedich-761	181	7	,	,	PUNCT
biomedich-761	181	8	b.	b.	PROPN
biomedich-761	181	9	,	,	PUNCT
biomedich-761	181	10	anjani	anjani	PROPN
biomedich-761	181	11	,	,	PUNCT
biomedich-761	181	12	r.	r.	PROPN
biomedich-761	181	13	,	,	PUNCT
biomedich-761	181	14	&	&	CCONJ
biomedich-761	181	15	annuria	annuria	PROPN
biomedich-761	181	16	,	,	PUNCT
biomedich-761	181	17	n.	n.	PROPN
biomedich-761	181	18	f.	f.	PROPN
biomedich-761	181	19	(	(	PUNCT
biomedich-761	181	20	2020	2020	NUM
biomedich-761	181	21	)	)	PUNCT
biomedich-761	181	22	.	.	PUNCT
biomedich-761	182	1	solid	solid	ADJ
biomedich-761	182	2	self	self	NOUN
biomedich-761	182	3	nano	nano	NOUN
biomedich-761	182	4	emulsifying	emulsify	VERB
biomedich-761	182	5	drug	drug	NOUN
biomedich-761	182	6	delivery	delivery	NOUN
biomedich-761	182	7	system	system	NOUN
biomedich-761	182	8	(	(	PUNCT
biomedich-761	182	9	solid	solid	ADJ
biomedich-761	182	10	snedds	snedd	NOUN
biomedich-761	182	11	)	)	PUNCT
biomedich-761	182	12	of	of	ADP
biomedich-761	182	13	mefenamic	mefenamic	ADJ
biomedich-761	182	14	acid	acid	NOUN
biomedich-761	182	15	:	:	PUNCT
biomedich-761	182	16	formula	formula	NOUN
biomedich-761	182	17	optimization	optimization	NOUN
biomedich-761	182	18	using	use	VERB
biomedich-761	182	19	aerosil	aerosil	NOUN
biomedich-761	182	20	®	®	NOUN
biomedich-761	182	21	-200	-200	PROPN
biomedich-761	182	22	and	and	CCONJ
biomedich-761	182	23	avicel	avicel	VERB
biomedich-761	182	24	®	®	NOUN
biomedich-761	182	25	ph-101	ph-101	NOUN
biomedich-761	182	26	with	with	ADP
biomedich-761	182	27	factorial	factorial	ADJ
biomedich-761	182	28	design	design	NOUN
biomedich-761	182	29	.	.	PUNCT
biomedich-761	183	1	international	international	ADJ
biomedich-761	183	2	research	research	PROPN
biomedich-761	183	3	journal	journal	PROPN
biomedich-761	183	4	of	of	ADP
biomedich-761	183	5	pharmacy	pharmacy	NOUN
biomedich-761	183	6	,	,	PUNCT
biomedich-761	183	7	11(2	11(2	NUM
biomedich-761	183	8	)	)	PUNCT
biomedich-761	183	9	,	,	PUNCT
biomedich-761	183	10	25–31	25–31	NUM
biomedich-761	183	11	.	.	PUNCT
biomedich-761	184	1	https://doi.org/10.7897/2230-8407.110215	https://doi.org/10.7897/2230-8407.110215	PROPN
biomedich-761	184	2	mehta	mehta	PROPN
biomedich-761	184	3	,	,	PUNCT
biomedich-761	184	4	d.	d.	PROPN
biomedich-761	184	5	,	,	PUNCT
biomedich-761	184	6	parejiya	parejiya	PROPN
biomedich-761	184	7	,	,	PUNCT
biomedich-761	184	8	p.	p.	PROPN
biomedich-761	184	9	b.	b.	PROPN
biomedich-761	184	10	,	,	PUNCT
biomedich-761	184	11	patel	patel	PROPN
biomedich-761	184	12	,	,	PUNCT
biomedich-761	184	13	h.	h.	PROPN
biomedich-761	184	14	,	,	PUNCT
biomedich-761	184	15	trivedi	trivedi	PROPN
biomedich-761	184	16	,	,	PUNCT
biomedich-761	184	17	p.	p.	PROPN
biomedich-761	184	18	,	,	PUNCT
biomedich-761	184	19	suthar	suthar	PROPN
biomedich-761	184	20	,	,	PUNCT
biomedich-761	184	21	d.	d.	PROPN
biomedich-761	184	22	,	,	PUNCT
biomedich-761	184	23	&	&	CCONJ
biomedich-761	184	24	shelat	shelat	PROPN
biomedich-761	184	25	,	,	PUNCT
biomedich-761	184	26	p.	p.	NOUN
biomedich-761	184	27	(	(	PUNCT
biomedich-761	184	28	2016	2016	NUM
biomedich-761	184	29	)	)	PUNCT
biomedich-761	184	30	.	.	PUNCT
biomedich-761	185	1	factorial	factorial	NOUN
biomedich-761	185	2	design	design	PROPN
biomedich-761	185	3	assisted	assist	VERB
biomedich-761	185	4	ph	ph	ADJ
biomedich-761	185	5	-	-	ADJ
biomedich-761	185	6	independent	independent	ADJ
biomedich-761	185	7	delivery	delivery	NOUN
biomedich-761	185	8	system	system	NOUN
biomedich-761	185	9	of	of	ADP
biomedich-761	185	10	poorly	poorly	ADV
biomedich-761	185	11	soluble	soluble	ADJ
biomedich-761	185	12	drug	drug	NOUN
biomedich-761	185	13	cinnarizine	cinnarizine	NOUN
biomedich-761	185	14	.	.	PUNCT
biomedich-761	186	1	asian	asian	ADJ
biomedich-761	186	2	journal	journal	PROPN
biomedich-761	186	3	of	of	ADP
biomedich-761	186	4	pharmaceutics	pharmaceutic	NOUN
biomedich-761	186	5	,	,	PUNCT
biomedich-761	186	6	10(3	10(3	NUM
biomedich-761	186	7	)	)	PUNCT
biomedich-761	186	8	.	.	PUNCT
biomedich-761	187	1	https://doi.org/10.22377/ajp.v10i3.722	https://doi.org/10.22377/ajp.v10i3.722	DET
biomedich-761	187	2	miller	miller	PROPN
biomedich-761	187	3	,	,	PUNCT
biomedich-761	187	4	j.	j.	PROPN
biomedich-761	187	5	m.	m.	PROPN
biomedich-761	187	6	,	,	PUNCT
biomedich-761	187	7	beig	beig	PROPN
biomedich-761	187	8	,	,	PUNCT
biomedich-761	187	9	a.	a.	PROPN
biomedich-761	187	10	,	,	PUNCT
biomedich-761	187	11	carr	carr	PROPN
biomedich-761	187	12	,	,	PUNCT
biomedich-761	187	13	r.	r.	PROPN
biomedich-761	187	14	a.	a.	PROPN
biomedich-761	187	15	,	,	PUNCT
biomedich-761	187	16	spence	spence	PROPN
biomedich-761	187	17	,	,	PUNCT
biomedich-761	187	18	j.	j.	PROPN
biomedich-761	187	19	k.	k.	PROPN
biomedich-761	187	20	,	,	PUNCT
biomedich-761	187	21	&	&	CCONJ
biomedich-761	187	22	dahan	dahan	PROPN
biomedich-761	187	23	,	,	PUNCT
biomedich-761	187	24	a.	a.	NOUN
biomedich-761	187	25	(	(	PUNCT
biomedich-761	187	26	2012	2012	NUM
biomedich-761	187	27	)	)	PUNCT
biomedich-761	187	28	.	.	PUNCT
biomedich-761	188	1	a	a	DET
biomedich-761	188	2	win	win	NOUN
biomedich-761	188	3	–	–	PUNCT
biomedich-761	188	4	win	win	NOUN
biomedich-761	188	5	solution	solution	NOUN
biomedich-761	188	6	in	in	ADP
biomedich-761	188	7	oral	oral	ADJ
biomedich-761	188	8	delivery	delivery	NOUN
biomedich-761	188	9	of	of	ADP
biomedich-761	188	10	lipophilic	lipophilic	ADJ
biomedich-761	188	11	drugs	drug	NOUN
biomedich-761	188	12	:	:	PUNCT
biomedich-761	188	13	supersaturation	supersaturation	NOUN
biomedich-761	188	14	via	via	ADP
biomedich-761	188	15	amorphous	amorphous	ADJ
biomedich-761	188	16	solid	solid	ADJ
biomedich-761	188	17	dispersions	dispersion	NOUN
biomedich-761	188	18	increases	increase	VERB
biomedich-761	188	19	apparent	apparent	ADJ
biomedich-761	188	20	solubility	solubility	NOUN
biomedich-761	188	21	without	without	ADP
biomedich-761	188	22	sacrifice	sacrifice	NOUN
biomedich-761	188	23	of	of	ADP
biomedich-761	188	24	intestinal	intestinal	ADJ
biomedich-761	188	25	membrane	membrane	NOUN
biomedich-761	188	26	permeability	permeability	NOUN
biomedich-761	188	27	.	.	PUNCT
biomedich-761	189	1	molecular	molecular	ADJ
biomedich-761	189	2	pharmaceutics	pharmaceutic	NOUN
biomedich-761	189	3	,	,	PUNCT
biomedich-761	189	4	9(7	9(7	NUM
biomedich-761	189	5	)	)	PUNCT
biomedich-761	189	6	,	,	PUNCT
biomedich-761	189	7	2009–2016	2009–2016	NUM
biomedich-761	189	8	.	.	PUNCT
biomedich-761	190	1	https://doi.org/10.1021/mp300104s	https://doi.org/10.1021/mp300104s	PROPN
biomedich-761	190	2	mukesh	mukesh	PROPN
biomedich-761	190	3	p.	p.	PROPN
biomedich-761	190	4	;	;	PUNCT
biomedich-761	191	1	bansal	bansal	NOUN
biomedich-761	191	2	,	,	PUNCT
biomedich-761	191	3	a.	a.	PROPN
biomedich-761	191	4	;	;	PUNCT
biomedich-761	191	5	kashyap	kashyap	PROPN
biomedich-761	191	6	,	,	PUNCT
biomedich-761	191	7	mahesh	mahesh	PROPN
biomedich-761	191	8	c	c	PROPN
biomedich-761	191	9	;	;	PUNCT
biomedich-761	191	10	mandal	mandal	PROPN
biomedich-761	191	11	,	,	PUNCT
biomedich-761	191	12	s.	s.	PROPN
biomedich-761	191	13	;	;	PUNCT
biomedich-761	191	14	sathe	sathe	PROPN
biomedich-761	191	15	,	,	PUNCT
biomedich-761	191	16	v.	v.	PROPN
biomedich-761	191	17	;	;	PUNCT
biomedich-761	191	18	sangamwar	sangamwar	NOUN
biomedich-761	191	19	,	,	PUNCT
biomedich-761	191	20	a.	a.	PROPN
biomedich-761	191	21	,	,	PUNCT
biomedich-761	191	22	s.	s.	PROPN
biomedich-761	191	23	j.	j.	PROPN
biomedich-761	191	24	(	(	PUNCT
biomedich-761	191	25	2021	2021	NUM
biomedich-761	191	26	)	)	PUNCT
biomedich-761	191	27	.	.	PUNCT
biomedich-761	192	1	amorphous	amorphous	ADJ
biomedich-761	192	2	salts	salt	NOUN
biomedich-761	192	3	solid	solid	ADJ
biomedich-761	192	4	dispersions	dispersion	NOUN
biomedich-761	192	5	of	of	ADP
biomedich-761	192	6	celecoxib	celecoxib	NOUN
biomedich-761	192	7	:	:	PUNCT
biomedich-761	192	8	enhanced	enhanced	ADJ
biomedich-761	192	9	biopharmaceutical	biopharmaceutical	ADJ
biomedich-761	192	10	performance	performance	NOUN
biomedich-761	192	11	and	and	CCONJ
biomedich-761	192	12	physical	physical	ADJ
biomedich-761	192	13	stability	stability	NOUN
biomedich-761	192	14	.	.	PUNCT
biomedich-761	193	1	molecular	molecular	ADJ
biomedich-761	193	2	pharmaceutics	pharmaceutic	NOUN
biomedich-761	193	3	,	,	PUNCT
biomedich-761	193	4	18	18	NUM
biomedich-761	193	5	,	,	PUNCT
biomedich-761	193	6	2142–2156	2142–2156	NUM
biomedich-761	193	7	.	.	PUNCT
biomedich-761	194	1	https://doi.org/10.1021/acs.molpharmaceut.1c00144	https://doi.org/10.1021/acs.molpharmaceut.1c00144	X
biomedich-761	194	2	nandi	nandi	PROPN
biomedich-761	194	3	,	,	PUNCT
biomedich-761	194	4	u.	u.	PROPN
biomedich-761	194	5	,	,	PUNCT
biomedich-761	194	6	ajiboye	ajiboye	VERB
biomedich-761	194	7	,	,	PUNCT
biomedich-761	194	8	a.	a.	PROPN
biomedich-761	194	9	l.	l.	PROPN
biomedich-761	194	10	,	,	PUNCT
biomedich-761	194	11	patel	patel	PROPN
biomedich-761	194	12	,	,	PUNCT
biomedich-761	194	13	p.	p.	PROPN
biomedich-761	194	14	,	,	PUNCT
biomedich-761	194	15	douroumis	douroumis	PROPN
biomedich-761	194	16	,	,	PUNCT
biomedich-761	194	17	d.	d.	PROPN
biomedich-761	194	18	,	,	PUNCT
biomedich-761	194	19	&	&	CCONJ
biomedich-761	194	20	trivedi	trivedi	PROPN
biomedich-761	194	21	,	,	PUNCT
biomedich-761	194	22	v.	v.	PROPN
biomedich-761	194	23	(	(	PUNCT
biomedich-761	194	24	2021	2021	NUM
biomedich-761	194	25	)	)	PUNCT
biomedich-761	194	26	.	.	PUNCT
biomedich-761	195	1	preparation	preparation	NOUN
biomedich-761	195	2	of	of	ADP
biomedich-761	195	3	solid	solid	ADJ
biomedich-761	195	4	dispersions	dispersion	NOUN
biomedich-761	195	5	of	of	ADP
biomedich-761	195	6	simvastatin	simvastatin	NOUN
biomedich-761	195	7	and	and	CCONJ
biomedich-761	195	8	soluplus	soluplus	ADJ
biomedich-761	195	9	using	use	VERB
biomedich-761	195	10	a	a	DET
biomedich-761	195	11	single	single	ADJ
biomedich-761	195	12	-	-	PUNCT
biomedich-761	195	13	step	step	NOUN
biomedich-761	195	14	organic	organic	ADJ
biomedich-761	195	15	solvent	solvent	NOUN
biomedich-761	195	16	-	-	PUNCT
biomedich-761	195	17	free	free	ADJ
biomedich-761	195	18	supercritical	supercritical	ADJ
biomedich-761	195	19	fluid	fluid	NOUN
biomedich-761	195	20	process	process	NOUN
biomedich-761	195	21	for	for	ADP
biomedich-761	195	22	the	the	DET
biomedich-761	195	23	drug	drug	NOUN
biomedich-761	195	24	solubility	solubility	NOUN
biomedich-761	195	25	and	and	CCONJ
biomedich-761	195	26	dissolution	dissolution	NOUN
biomedich-761	195	27	rate	rate	NOUN
biomedich-761	195	28	enhancement	enhancement	NOUN
biomedich-761	195	29	.	.	PUNCT
biomedich-761	196	1	pharmaceuticals	pharmaceutical	NOUN
biomedich-761	196	2	,	,	PUNCT
biomedich-761	196	3	14(9	14(9	NUM
biomedich-761	196	4	)	)	PUNCT
biomedich-761	196	5	,	,	PUNCT
biomedich-761	196	6	846	846	NUM
biomedich-761	196	7	.	.	PUNCT
biomedich-761	197	1	https://doi.org/10.3390/ph14090846	https://doi.org/10.3390/ph14090846	NOUN
biomedich-761	197	2	neeharika	neeharika	NOUN
biomedich-761	197	3	,	,	PUNCT
biomedich-761	197	4	m.	m.	NOUN
biomedich-761	197	5	s.	s.	PROPN
biomedich-761	197	6	,	,	PUNCT
biomedich-761	197	7	&	&	CCONJ
biomedich-761	197	8	jyothi	jyothi	PROPN
biomedich-761	197	9	,	,	PUNCT
biomedich-761	197	10	b.	b.	PROPN
biomedich-761	197	11	j.	j.	PROPN
biomedich-761	197	12	(	(	PUNCT
biomedich-761	197	13	2021	2021	NUM
biomedich-761	197	14	)	)	PUNCT
biomedich-761	197	15	.	.	PUNCT
biomedich-761	198	1	preparation	preparation	NOUN
biomedich-761	198	2	and	and	CCONJ
biomedich-761	198	3	evaluation	evaluation	NOUN
biomedich-761	198	4	of	of	ADP
biomedich-761	198	5	zafirlukast	zafirlukast	NOUN
biomedich-761	198	6	compression	compression	NOUN
biomedich-761	198	7	coated	coat	VERB
biomedich-761	198	8	tablets	tablet	NOUN
biomedich-761	198	9	for	for	ADP
biomedich-761	198	10	chronotherapeutic	chronotherapeutic	ADJ
biomedich-761	198	11	drug	drug	NOUN
biomedich-761	198	12	delivery	delivery	NOUN
biomedich-761	198	13	.	.	PUNCT
biomedich-761	199	1	journal	journal	NOUN
biomedich-761	199	2	of	of	ADP
biomedich-761	199	3	pharmaceutical	pharmaceutical	PROPN
biomedich-761	199	4	research	research	PROPN
biomedich-761	199	5	international	international	PROPN
biomedich-761	199	6	,	,	PUNCT
biomedich-761	199	7	154–166	154–166	NUM
biomedich-761	199	8	.	.	PUNCT
biomedich-761	200	1	https://doi.org/10.9734/jpri/2021/v33i32b31757	https://doi.org/10.9734/jpri/2021/v33i32b31757	PROPN
biomedich-761	200	2	oyama	oyama	PROPN
biomedich-761	200	3	,	,	PUNCT
biomedich-761	200	4	s.	s.	PROPN
biomedich-761	200	5	,	,	PUNCT
biomedich-761	200	6	ogawa	ogawa	PROPN
biomedich-761	200	7	,	,	PUNCT
biomedich-761	200	8	n.	n.	PROPN
biomedich-761	200	9	,	,	PUNCT
biomedich-761	200	10	kawai	kawai	PROPN
biomedich-761	200	11	,	,	PUNCT
biomedich-761	200	12	k.	k.	PROPN
biomedich-761	200	13	,	,	PUNCT
biomedich-761	200	14	iwai	iwai	PROPN
biomedich-761	200	15	,	,	PUNCT
biomedich-761	200	16	k.	k.	PROPN
biomedich-761	200	17	,	,	PUNCT
biomedich-761	200	18	yasunaga	yasunaga	NOUN
biomedich-761	200	19	,	,	PUNCT
biomedich-761	200	20	t.	t.	PROPN
biomedich-761	200	21	,	,	PUNCT
biomedich-761	200	22	&	&	CCONJ
biomedich-761	200	23	yamamoto	yamamoto	PROPN
biomedich-761	200	24	,	,	PUNCT
biomedich-761	200	25	h.	h.	PROPN
biomedich-761	200	26	(	(	PUNCT
biomedich-761	200	27	2024	2024	NUM
biomedich-761	200	28	)	)	PUNCT
biomedich-761	200	29	.	.	PUNCT
biomedich-761	201	1	improved	improve	VERB
biomedich-761	201	2	dissolution	dissolution	NOUN
biomedich-761	201	3	properties	property	NOUN
biomedich-761	201	4	of	of	ADP
biomedich-761	201	5	coamorphous	coamorphous	ADJ
biomedich-761	201	6	probucol	probucol	NOUN
biomedich-761	201	7	with	with	ADP
biomedich-761	201	8	atorvastatin	atorvastatin	PROPN
biomedich-761	201	9	calcium	calcium	NOUN
biomedich-761	201	10	trihydrate	trihydrate	NOUN
biomedich-761	201	11	prepared	prepare	VERB
biomedich-761	201	12	by	by	ADP
biomedich-761	201	13	spray	spray	NOUN
biomedich-761	201	14	-	-	PUNCT
biomedich-761	201	15	drying	dry	VERB
biomedich-761	201	16	.	.	PUNCT
biomedich-761	202	1	chemical	chemical	NOUN
biomedich-761	202	2	and	and	CCONJ
biomedich-761	202	3	pharmaceutical	pharmaceutical	NOUN
biomedich-761	202	4	bulletin	bulletin	NOUN
biomedich-761	202	5	,	,	PUNCT
biomedich-761	202	6	72(2	72(2	NOUN
biomedich-761	202	7	)	)	PUNCT
biomedich-761	202	8	,	,	PUNCT
biomedich-761	202	9	190–199	190–199	NUM
biomedich-761	202	10	.	.	PUNCT
biomedich-761	203	1	https://doi.org/10.1248/cpb.c2300673	https://doi.org/10.1248/cpb.c2300673	PROPN
biomedich-761	203	2	park	park	PROPN
biomedich-761	203	3	,	,	PUNCT
biomedich-761	203	4	m.	m.	NOUN
biomedich-761	203	5	,	,	PUNCT
biomedich-761	203	6	kim	kim	PROPN
biomedich-761	203	7	,	,	PUNCT
biomedich-761	203	8	s.	s.	PROPN
biomedich-761	203	9	,	,	PUNCT
biomedich-761	203	10	&	&	CCONJ
biomedich-761	203	11	yoon	yoon	PROPN
biomedich-761	203	12	,	,	PUNCT
biomedich-761	203	13	h.	h.	PROPN
biomedich-761	203	14	(	(	PUNCT
biomedich-761	203	15	2018	2018	NUM
biomedich-761	203	16	)	)	PUNCT
biomedich-761	203	17	.	.	PUNCT
biomedich-761	204	1	enhancing	enhance	VERB
biomedich-761	204	2	the	the	DET
biomedich-761	204	3	dissolution	dissolution	NOUN
biomedich-761	204	4	and	and	CCONJ
biomedich-761	204	5	bioavailability	bioavailability	NOUN
biomedich-761	204	6	of	of	ADP
biomedich-761	204	7	poorly	poorly	ADV
biomedich-761	204	8	soluble	soluble	ADJ
biomedich-761	204	9	drugs	drug	NOUN
biomedich-761	204	10	through	through	ADP
biomedich-761	204	11	spherical	spherical	ADJ
biomedich-761	204	12	crystallization	crystallization	NOUN
biomedich-761	204	13	.	.	PUNCT
biomedich-761	205	1	international	international	ADJ
biomedich-761	205	2	journal	journal	PROPN
biomedich-761	205	3	of	of	ADP
biomedich-761	205	4	pharmaceutics	pharmaceutic	NOUN
biomedich-761	205	5	,	,	PUNCT
biomedich-761	205	6	537(1–2	537(1–2	NUM
biomedich-761	205	7	)	)	PUNCT
biomedich-761	205	8	,	,	PUNCT
biomedich-761	205	9	1–10	1–10	NOUN
biomedich-761	205	10	.	.	PUNCT
biomedich-761	206	1	patel	patel	PROPN
biomedich-761	206	2	,	,	PUNCT
biomedich-761	206	3	d.	d.	PROPN
biomedich-761	206	4	,	,	PUNCT
biomedich-761	206	5	pipaliya	pipaliya	PROPN
biomedich-761	206	6	,	,	PUNCT
biomedich-761	206	7	r.	r.	PROPN
biomedich-761	206	8	m.	m.	PROPN
biomedich-761	206	9	,	,	PUNCT
biomedich-761	206	10	&	&	CCONJ
biomedich-761	206	11	surti	surti	PROPN
biomedich-761	206	12	,	,	PUNCT
biomedich-761	206	13	n.	n.	PROPN
biomedich-761	206	14	(	(	PUNCT
biomedich-761	206	15	2015	2015	NUM
biomedich-761	206	16	)	)	PUNCT
biomedich-761	206	17	.	.	PUNCT
biomedich-761	207	1	liquisolid	liquisolid	ADJ
biomedich-761	207	2	tablets	tablet	NOUN
biomedich-761	207	3	for	for	ADP
biomedich-761	207	4	dissolution	dissolution	ADJ
biomedich-761	207	5	enhancement	enhancement	NOUN
biomedich-761	207	6	of	of	ADP
biomedich-761	207	7	a	a	DET
biomedich-761	207	8	hypolipidemic	hypolipidemic	ADJ
biomedich-761	207	9	drug	drug	NOUN
biomedich-761	207	10	.	.	PUNCT
biomedich-761	208	1	indian	indian	PROPN
biomedich-761	208	2	journal	journal	PROPN
biomedich-761	208	3	of	of	ADP
biomedich-761	208	4	pharmaceutical	pharmaceutical	NOUN
biomedich-761	208	5	sciences	science	NOUN
biomedich-761	208	6	,	,	PUNCT
biomedich-761	208	7	77(3	77(3	NUM
biomedich-761	208	8	)	)	PUNCT
biomedich-761	208	9	,	,	PUNCT
biomedich-761	208	10	290	290	NUM
biomedich-761	208	11	.	.	PUNCT
biomedich-761	209	1	https://doi.org/10.4103/0250-474x.159618	https://doi.org/10.4103/0250-474x.159618	PROPN
biomedich-761	209	2	pervaiz	pervaiz	PROPN
biomedich-761	209	3	,	,	PUNCT
biomedich-761	209	4	a.	a.	PROPN
biomedich-761	209	5	,	,	PUNCT
biomedich-761	209	6	saeed	saeed	PROPN
biomedich-761	209	7	,	,	PUNCT
biomedich-761	209	8	m.	m.	NOUN
biomedich-761	209	9	,	,	PUNCT
biomedich-761	209	10	anwar	anwar	PROPN
biomedich-761	209	11	,	,	PUNCT
biomedich-761	209	12	m.	m.	NOUN
biomedich-761	209	13	,	,	PUNCT
biomedich-761	209	14	mansoor	mansoor	PROPN
biomedich-761	209	15	,	,	PUNCT
biomedich-761	209	16	u.	u.	PROPN
biomedich-761	209	17	,	,	PUNCT
biomedich-761	209	18	shabbir	shabbir	PROPN
biomedich-761	209	19	,	,	PUNCT
biomedich-761	209	20	u.	u.	PROPN
biomedich-761	209	21	,	,	PUNCT
biomedich-761	209	22	&	&	CCONJ
biomedich-761	209	23	khalid	khalid	PROPN
biomedich-761	209	24	,	,	PUNCT
biomedich-761	209	25	m.	m.	NOUN
biomedich-761	209	26	(	(	PUNCT
biomedich-761	209	27	2023	2023	NUM
biomedich-761	209	28	)	)	PUNCT
biomedich-761	209	29	.	.	PUNCT
biomedich-761	210	1	preparation	preparation	NOUN
biomedich-761	210	2	and	and	CCONJ
biomedich-761	210	3	characterization	characterization	NOUN
biomedich-761	210	4	of	of	ADP
biomedich-761	210	5	self	self	NOUN
biomedich-761	210	6	emulsifying	emulsify	VERB
biomedich-761	210	7	solid	solid	ADJ
biomedich-761	210	8	dispersions	dispersion	NOUN
biomedich-761	210	9	of	of	ADP
biomedich-761	210	10	mebendazole	mebendazole	NOUN
biomedich-761	210	11	to	to	PART
biomedich-761	210	12	improve	improve	VERB
biomedich-761	210	13	solubility	solubility	NOUN
biomedich-761	210	14	.	.	PUNCT
biomedich-761	211	1	international	international	ADJ
biomedich-761	211	2	journal	journal	PROPN
biomedich-761	211	3	of	of	ADP
biomedich-761	211	4	pharmacy	pharmacy	NOUN
biomedich-761	211	5	&	&	CCONJ
biomedich-761	211	6	integrated	integrate	VERB
biomedich-761	211	7	health	health	NOUN
biomedich-761	211	8	sciences	science	NOUN
biomedich-761	211	9	,	,	PUNCT
biomedich-761	211	10	4(1	4(1	NOUN
biomedich-761	211	11	)	)	PUNCT
biomedich-761	211	12	.	.	PUNCT
biomedich-761	212	1	https://doi.org/10.56536/ijpihs.v4i1.77	https://doi.org/10.56536/ijpihs.v4i1.77	PROPN
biomedich-761	212	2	qian	qian	PROPN
biomedich-761	212	3	,	,	PUNCT
biomedich-761	212	4	s.	s.	PROPN
biomedich-761	212	5	,	,	PUNCT
biomedich-761	212	6	heng	heng	PROPN
biomedich-761	212	7	,	,	PUNCT
biomedich-761	212	8	w.	w.	PROPN
biomedich-761	212	9	,	,	PUNCT
biomedich-761	212	10	wei	wei	PROPN
biomedich-761	212	11	,	,	PUNCT
biomedich-761	212	12	y.	y.	PROPN
biomedich-761	212	13	,	,	PUNCT
biomedich-761	212	14	zhang	zhang	PROPN
biomedich-761	212	15	,	,	PUNCT
biomedich-761	212	16	j.	j.	PROPN
biomedich-761	212	17	,	,	PUNCT
biomedich-761	212	18	&	&	CCONJ
biomedich-761	212	19	gao	gao	PROPN
biomedich-761	212	20	,	,	PUNCT
biomedich-761	212	21	y.	y.	PROPN
biomedich-761	212	22	(	(	PUNCT
biomedich-761	212	23	2015	2015	NUM
biomedich-761	212	24	)	)	PUNCT
biomedich-761	212	25	.	.	PUNCT
biomedich-761	213	1	coamorphous	coamorphous	ADJ
biomedich-761	213	2	lurasidone	lurasidone	NOUN
biomedich-761	213	3	hydrochloride	hydrochloride	NOUN
biomedich-761	213	4	–	–	PUNCT
biomedich-761	213	5	saccharin	saccharin	NOUN
biomedich-761	213	6	with	with	ADP
biomedich-761	213	7	charge	charge	NOUN
biomedich-761	213	8	-	-	PUNCT
biomedich-761	213	9	assisted	assist	VERB
biomedich-761	213	10	hydrogen	hydrogen	NOUN
biomedich-761	213	11	bonding	bonding	NOUN
biomedich-761	213	12	interaction	interaction	NOUN
biomedich-761	213	13	shows	show	VERB
biomedich-761	213	14	improved	improve	VERB
biomedich-761	213	15	physical	physical	ADJ
biomedich-761	213	16	stability	stability	NOUN
biomedich-761	213	17	and	and	CCONJ
biomedich-761	213	18	enhanced	enhance	VERB
biomedich-761	213	19	dissolution	dissolution	NOUN
biomedich-761	213	20	with	with	ADP
biomedich-761	213	21	ph	ph	ADJ
biomedich-761	213	22	-	-	ADJ
biomedich-761	213	23	independent	independent	ADJ
biomedich-761	213	24	solubility	solubility	NOUN
biomedich-761	213	25	behavior	behavior	NOUN
biomedich-761	213	26	.	.	PUNCT
biomedich-761	214	1	crystal	crystal	NOUN
biomedich-761	214	2	growth	growth	PROPN
biomedich-761	214	3	&	&	CCONJ
biomedich-761	214	4	design	design	PROPN
biomedich-761	214	5	,	,	PUNCT
biomedich-761	214	6	15(6	15(6	NUM
biomedich-761	214	7	)	)	PUNCT
biomedich-761	214	8	,	,	PUNCT
biomedich-761	214	9	2920–2928	2920–2928	NUM
biomedich-761	214	10	.	.	PUNCT
biomedich-761	215	1	https://doi.org/10.1021/acs.cgd.5b00349	https://doi.org/10.1021/acs.cgd.5b00349	PROPN
biomedich-761	215	2	sanas	sanas	PROPN
biomedich-761	215	3	,	,	PUNCT
biomedich-761	215	4	m.	m.	NOUN
biomedich-761	215	5	n.	n.	PROPN
biomedich-761	215	6	,	,	PUNCT
biomedich-761	215	7	&	&	CCONJ
biomedich-761	215	8	pachpute	pachpute	NOUN
biomedich-761	215	9	,	,	PUNCT
biomedich-761	215	10	t.	t.	PROPN
biomedich-761	215	11	s.	s.	PROPN
biomedich-761	215	12	(	(	PUNCT
biomedich-761	215	13	2023	2023	NUM
biomedich-761	215	14	)	)	PUNCT
biomedich-761	215	15	.	.	PUNCT
biomedich-761	216	1	exploring	explore	VERB
biomedich-761	216	2	the	the	DET
biomedich-761	216	3	potential	potential	NOUN
biomedich-761	216	4	of	of	ADP
biomedich-761	216	5	ketoprofen	ketoprofen	NOUN
biomedich-761	216	6	nanosuspension	nanosuspension	NOUN
biomedich-761	216	7	:	:	PUNCT
biomedich-761	216	8	in	in	ADP
biomedich-761	216	9	vitro	vitro	X
biomedich-761	216	10	and	and	CCONJ
biomedich-761	216	11	in	in	ADP
biomedich-761	216	12	vivo	vivo	ADJ
biomedich-761	216	13	insights	insight	NOUN
biomedich-761	216	14	into	into	ADP
biomedich-761	216	15	drug	drug	NOUN
biomedich-761	216	16	release	release	NOUN
biomedich-761	216	17	and	and	CCONJ
biomedich-761	216	18	bioavailability	bioavailability	NOUN
biomedich-761	216	19	.	.	PUNCT
biomedich-761	217	1	journal	journal	PROPN
biomedich-761	217	2	of	of	ADP
biomedich-761	217	3	drug	drug	NOUN
biomedich-761	217	4	delivery	delivery	NOUN
biomedich-761	217	5	and	and	CCONJ
biomedich-761	217	6	therapeutics	therapeutic	NOUN
biomedich-761	217	7	,	,	PUNCT
biomedich-761	217	8	13(6	13(6	NUM
biomedich-761	217	9	)	)	PUNCT
biomedich-761	217	10	,	,	PUNCT
biomedich-761	217	11	152–158	152–158	NUM
biomedich-761	217	12	.	.	PUNCT
biomedich-761	218	1	https://doi.org/10.22270/jddt.v13i6.5890	https://doi.org/10.22270/jddt.v13i6.5890	NOUN
biomedich-761	218	2	sapkal	sapkal	NOUN
biomedich-761	218	3	,	,	PUNCT
biomedich-761	218	4	s.	s.	PROPN
biomedich-761	218	5	b.	b.	PROPN
biomedich-761	218	6	,	,	PUNCT
biomedich-761	218	7	adhao	adhao	PROPN
biomedich-761	218	8	,	,	PUNCT
biomedich-761	218	9	v.	v.	PROPN
biomedich-761	218	10	s.	s.	PROPN
biomedich-761	218	11	,	,	PUNCT
biomedich-761	218	12	thenge	thenge	PROPN
biomedich-761	218	13	,	,	PUNCT
biomedich-761	218	14	r.	r.	PROPN
biomedich-761	218	15	r.	r.	PROPN
biomedich-761	218	16	,	,	PUNCT
biomedich-761	218	17	darakhe	darakhe	PROPN
biomedich-761	218	18	,	,	PUNCT
biomedich-761	218	19	r.	r.	PROPN
biomedich-761	218	20	a.	a.	PROPN
biomedich-761	218	21	,	,	PUNCT
biomedich-761	218	22	shinde	shinde	PROPN
biomedich-761	218	23	,	,	PUNCT
biomedich-761	218	24	s.	s.	PROPN
biomedich-761	218	25	a.	a.	PROPN
biomedich-761	218	26	,	,	PUNCT
biomedich-761	218	27	&	&	CCONJ
biomedich-761	218	28	shrikhande	shrikhande	PROPN
biomedich-761	218	29	,	,	PUNCT
biomedich-761	218	30	v.	v.	ADP
biomedich-761	218	31	n.	n.	NOUN
biomedich-761	218	32	(	(	PUNCT
biomedich-761	218	33	2018	2018	NUM
biomedich-761	218	34	)	)	PUNCT
biomedich-761	218	35	.	.	PUNCT
biomedich-761	219	1	formulation	formulation	NOUN
biomedich-761	219	2	and	and	CCONJ
biomedich-761	219	3	characterization	characterization	NOUN
biomedich-761	219	4	of	of	ADP
biomedich-761	219	5	etoricoxib	etoricoxib	ADJ
biomedich-761	219	6	solid	solid	ADJ
biomedich-761	219	7	dispersion	dispersion	NOUN
biomedich-761	219	8	using	use	VERB
biomedich-761	219	9	natural	natural	ADJ
biomedich-761	219	10	polymers	polymer	NOUN
biomedich-761	219	11	.	.	PUNCT
biomedich-761	220	1	turkish	turkish	ADJ
biomedich-761	220	2	journal	journal	NOUN
biomedich-761	220	3	of	of	ADP
biomedich-761	220	4	pharmaceutical	pharmaceutical	NOUN
biomedich-761	220	5	sciences	science	NOUN
biomedich-761	220	6	.	.	PUNCT
biomedich-761	221	1	https://doi.org/10.4274/tjps.04880	https://doi.org/10.4274/tjps.04880	VERB
biomedich-761	221	2	sharma	sharma	NOUN
biomedich-761	221	3	,	,	PUNCT
biomedich-761	221	4	p.	p.	NOUN
biomedich-761	221	5	,	,	PUNCT
biomedich-761	221	6	kaur	kaur	PROPN
biomedich-761	221	7	,	,	PUNCT
biomedich-761	221	8	t.	t.	PROPN
biomedich-761	221	9	,	,	PUNCT
biomedich-761	221	10	&	&	CCONJ
biomedich-761	221	11	singh	singh	PROPN
biomedich-761	221	12	,	,	PUNCT
biomedich-761	221	13	a.	a.	NOUN
biomedich-761	221	14	(	(	PUNCT
biomedich-761	221	15	2017	2017	NUM
biomedich-761	221	16	)	)	PUNCT
biomedich-761	221	17	.	.	PUNCT
biomedich-761	222	1	solubility	solubility	NOUN
biomedich-761	222	2	and	and	CCONJ
biomedich-761	222	3	dissolution	dissolution	NOUN
biomedich-761	222	4	enhancement	enhancement	NOUN
biomedich-761	222	5	of	of	ADP
biomedich-761	222	6	water	water	NOUN
biomedich-761	222	7	insoluble	insoluble	ADJ
biomedich-761	222	8	drug	drug	NOUN
biomedich-761	222	9	by	by	ADP
biomedich-761	222	10	using	use	VERB
biomedich-761	222	11	different	different	ADJ
biomedich-761	222	12	hydrophillic	hydrophillic	ADJ
biomedich-761	222	13	carriers	carrier	NOUN
biomedich-761	222	14	and	and	CCONJ
biomedich-761	222	15	formulated	formulate	VERB
biomedich-761	222	16	into	into	ADP
biomedich-761	222	17	tablet	tablet	ADJ
biomedich-761	222	18	dosage	dosage	NOUN
biomedich-761	222	19	form	form	NOUN
biomedich-761	222	20	.	.	PUNCT
biomedich-761	223	1	journal	journal	NOUN
biomedich-761	223	2	of	of	ADP
biomedich-761	223	3	drug	drug	NOUN
biomedich-761	223	4	delivery	delivery	NOUN
biomedich-761	223	5	and	and	CCONJ
biomedich-761	223	6	therapeutics	therapeutic	NOUN
biomedich-761	223	7	,	,	PUNCT
biomedich-761	223	8	7(5	7(5	NUM
biomedich-761	223	9	)	)	PUNCT
biomedich-761	223	10	.	.	PUNCT
biomedich-761	224	1	https://doi.org/10.22270/jddt.v7i5.1491	https://doi.org/10.22270/jddt.v7i5.1491	PROPN
biomedich-761	224	2	suknuntha	suknuntha	NOUN
biomedich-761	224	3	,	,	PUNCT
biomedich-761	224	4	k.	k.	PROPN
biomedich-761	224	5	,	,	PUNCT
biomedich-761	224	6	khumpirapang	khumpirapang	PROPN
biomedich-761	224	7	,	,	PUNCT
biomedich-761	224	8	n.	n.	NOUN
biomedich-761	224	9	,	,	PUNCT
biomedich-761	224	10	tantishaiyakul	tantishaiyakul	ADJ
biomedich-761	224	11	,	,	PUNCT
biomedich-761	224	12	v.	v.	ADV
biomedich-761	224	13	,	,	PUNCT
biomedich-761	224	14	&	&	CCONJ
biomedich-761	224	15	okonogi	okonogi	PROPN
biomedich-761	224	16	,	,	PUNCT
biomedich-761	224	17	s.	s.	PROPN
biomedich-761	224	18	(	(	PUNCT
biomedich-761	224	19	2023	2023	NUM
biomedich-761	224	20	)	)	PUNCT
biomedich-761	224	21	.	.	PUNCT
biomedich-761	225	1	solubility	solubility	NOUN
biomedich-761	225	2	and	and	CCONJ
biomedich-761	225	3	physical	physical	ADJ
biomedich-761	225	4	stability	stability	NOUN
biomedich-761	225	5	enhancement	enhancement	NOUN
biomedich-761	225	6	of	of	ADP
biomedich-761	225	7	loratadine	loratadine	NOUN
biomedich-761	225	8	by	by	ADP
biomedich-761	225	9	preparation	preparation	NOUN
biomedich-761	225	10	of	of	ADP
biomedich-761	225	11	co	co	ADJ
biomedich-761	225	12	-	-	ADJ
biomedich-761	225	13	amorphous	amorphous	ADJ
biomedich-761	225	14	solid	solid	ADJ
biomedich-761	225	15	dispersion	dispersion	NOUN
biomedich-761	225	16	with	with	ADP
biomedich-761	225	17	chlorpheniramine	chlorpheniramine	NOUN
biomedich-761	225	18	and	and	CCONJ
biomedich-761	225	19	polyvinylpyrrolidone	polyvinylpyrrolidone	NOUN
biomedich-761	225	20	.	.	PUNCT
biomedich-761	226	1	pharmaceutics	pharmaceutic	NOUN
biomedich-761	226	2	,	,	PUNCT
biomedich-761	226	3	15(11	15(11	NUM
biomedich-761	226	4	)	)	PUNCT
biomedich-761	226	5	,	,	PUNCT
biomedich-761	226	6	2558	2558	NUM
biomedich-761	226	7	.	.	PUNCT
biomedich-761	227	1	https://doi.org/10.3390/pharmaceutics15112558	https://doi.org/10.3390/pharmaceutics15112558	PROPN
biomedich-761	227	2	thayyil	thayyil	PROPN
biomedich-761	227	3	,	,	PUNCT
biomedich-761	227	4	a.	a.	PROPN
biomedich-761	227	5	r.	r.	PROPN
biomedich-761	227	6	,	,	PUNCT
biomedich-761	227	7	thimmasetty	thimmasetty	PROPN
biomedich-761	227	8	,	,	PUNCT
biomedich-761	227	9	j.	j.	PROPN
biomedich-761	227	10	,	,	PUNCT
biomedich-761	227	11	shashank	shashank	PROPN
biomedich-761	227	12	,	,	PUNCT
biomedich-761	227	13	n.	n.	PROPN
biomedich-761	227	14	,	,	PUNCT
biomedich-761	227	15	&	&	CCONJ
biomedich-761	227	16	kamath	kamath	PROPN
biomedich-761	227	17	,	,	PUNCT
biomedich-761	227	18	s.	s.	PROPN
biomedich-761	227	19	(	(	PUNCT
biomedich-761	227	20	2020	2020	NUM
biomedich-761	227	21	)	)	PUNCT
biomedich-761	227	22	.	.	PUNCT
biomedich-761	228	1	pharmaceutical	pharmaceutical	PROPN
biomedich-761	228	2	co	co	NOUN
biomedich-761	228	3	-	-	NOUN
biomedich-761	228	4	crystallization	crystallization	NOUN
biomedich-761	228	5	:	:	PUNCT
biomedich-761	228	6	regulatory	regulatory	ADJ
biomedich-761	228	7	aspects	aspect	NOUN
biomedich-761	228	8	,	,	PUNCT
biomedich-761	228	9	design	design	NOUN
biomedich-761	228	10	,	,	PUNCT
biomedich-761	228	11	characterization	characterization	NOUN
biomedich-761	228	12	,	,	PUNCT
biomedich-761	228	13	and	and	CCONJ
biomedich-761	228	14	applications	application	NOUN
biomedich-761	228	15	.	.	PUNCT
biomedich-761	229	1	advanced	advanced	ADJ
biomedich-761	229	2	pharmaceutical	pharmaceutical	ADJ
biomedich-761	229	3	bulletin	bulletin	NOUN
biomedich-761	229	4	,	,	PUNCT
biomedich-761	229	5	10(2	10(2	NUM
biomedich-761	229	6	)	)	PUNCT
biomedich-761	229	7	,	,	PUNCT
biomedich-761	229	8	203–212	203–212	NUM
biomedich-761	229	9	.	.	PUNCT
biomedich-761	230	1	https://doi.org/10.34172/apb.2020.024	https://doi.org/10.34172/apb.2020.024	VERB
biomedich-761	230	2	turek	turek	NOUN
biomedich-761	230	3	,	,	PUNCT
biomedich-761	230	4	m.	m.	NOUN
biomedich-761	230	5	,	,	PUNCT
biomedich-761	230	6	różycka‐sokołowska	różycka‐sokołowska	PROPN
biomedich-761	230	7	,	,	PUNCT
biomedich-761	230	8	e.	e.	PROPN
biomedich-761	230	9	,	,	PUNCT
biomedich-761	230	10	koprowski	koprowski	PROPN
biomedich-761	230	11	,	,	PUNCT
biomedich-761	230	12	m.	m.	NOUN
biomedich-761	230	13	,	,	PUNCT
biomedich-761	230	14	marciniak	marciniak	PROPN
biomedich-761	230	15	,	,	PUNCT
biomedich-761	230	16	b.	b.	PROPN
biomedich-761	230	17	,	,	PUNCT
biomedich-761	230	18	&	&	CCONJ
biomedich-761	230	19	bałczewski	bałczewski	PROPN
biomedich-761	230	20	,	,	PUNCT
biomedich-761	230	21	p.	p.	NOUN
biomedich-761	230	22	(	(	PUNCT
biomedich-761	230	23	2021	2021	NUM
biomedich-761	230	24	)	)	PUNCT
biomedich-761	230	25	.	.	PUNCT
biomedich-761	231	1	role	role	NOUN
biomedich-761	231	2	of	of	ADP
biomedich-761	231	3	hydrogen	hydrogen	NOUN
biomedich-761	231	4	bonds	bond	NOUN
biomedich-761	231	5	in	in	ADP
biomedich-761	231	6	formation	formation	NOUN
biomedich-761	231	7	of	of	ADP
biomedich-761	231	8	co	co	ADJ
biomedich-761	231	9	-	-	ADJ
biomedich-761	231	10	amorphous	amorphous	ADJ
biomedich-761	231	11	valsartan	valsartan	PROPN
biomedich-761	231	12	/	/	SYM
biomedich-761	231	13	nicotinamide	nicotinamide	NOUN
biomedich-761	231	14	compositions	composition	NOUN
biomedich-761	231	15	of	of	ADP
biomedich-761	231	16	high	high	ADJ
biomedich-761	231	17	solubility	solubility	NOUN
biomedich-761	231	18	and	and	CCONJ
biomedich-761	231	19	durability	durability	NOUN
biomedich-761	231	20	with	with	ADP
biomedich-761	231	21	antihypertension	antihypertension	NOUN
biomedich-761	231	22	and	and	CCONJ
biomedich-761	231	23	anti	anti	ADJ
biomedich-761	231	24	-	-	ADJ
biomedich-761	231	25	covid-19	covid-19	ADJ
biomedich-761	231	26	potential	potential	NOUN
biomedich-761	231	27	.	.	PUNCT
biomedich-761	232	1	molecular	molecular	ADJ
biomedich-761	232	2	pharmaceutics	pharmaceutic	NOUN
biomedich-761	232	3	,	,	PUNCT
biomedich-761	232	4	18(5	18(5	NUM
biomedich-761	232	5	)	)	PUNCT
biomedich-761	232	6	,	,	PUNCT
biomedich-761	232	7	1970–1984	1970–1984	NUM
biomedich-761	232	8	.	.	PUNCT
biomedich-761	233	1	https://doi.org/10.1021/acs.molpharmaceut.0c01096	https://doi.org/10.1021/acs.molpharmaceut.0c01096	PUNCT
biomedich-761	233	2	indra	indra	PROPN
biomedich-761	233	3	et	et	PROPN
biomedich-761	233	4	al	al	PROPN
biomedich-761	233	5	.	.	PROPN
biomedich-761	233	6	–	–	PUNCT
biomedich-761	233	7	crystalline	crystalline	X
biomedich-761	233	8	solid	solid	ADJ
biomedich-761	233	9	dispersion	dispersion	NOUN
biomedich-761	233	10	for	for	ADP
biomedich-761	233	11	mefenamic	mefenamic	ADJ
biomedich-761	233	12	acid	acid	NOUN
biomedich-761	233	13	607	607	NUM
biomedich-761	233	14	vasanani	vasanani	PROPN
biomedich-761	233	15	,	,	PUNCT
biomedich-761	233	16	p.	p.	PROPN
biomedich-761	233	17	r.	r.	PROPN
biomedich-761	233	18	,	,	PUNCT
biomedich-761	233	19	patel	patel	PROPN
biomedich-761	233	20	,	,	PUNCT
biomedich-761	233	21	l.	l.	PROPN
biomedich-761	233	22	d.	d.	PROPN
biomedich-761	233	23	,	,	PUNCT
biomedich-761	233	24	&	&	CCONJ
biomedich-761	233	25	detroja	detroja	PROPN
biomedich-761	233	26	,	,	PUNCT
biomedich-761	233	27	c.	c.	PROPN
biomedich-761	233	28	(	(	PUNCT
biomedich-761	233	29	2016	2016	NUM
biomedich-761	233	30	)	)	PUNCT
biomedich-761	233	31	.	.	PUNCT
biomedich-761	234	1	formulation	formulation	NOUN
biomedich-761	234	2	and	and	CCONJ
biomedich-761	234	3	development	development	NOUN
biomedich-761	234	4	of	of	ADP
biomedich-761	234	5	stable	stable	ADJ
biomedich-761	234	6	metaxalone	metaxalone	NOUN
biomedich-761	234	7	nanosuspension	nanosuspension	NOUN
biomedich-761	234	8	using	use	VERB
biomedich-761	234	9	32	32	NUM
biomedich-761	234	10	factorial	factorial	ADJ
biomedich-761	234	11	design	design	NOUN
biomedich-761	234	12	.	.	PUNCT
biomedich-761	235	1	international	international	ADJ
biomedich-761	235	2	journal	journal	PROPN
biomedich-761	235	3	of	of	ADP
biomedich-761	235	4	pharmaceutical	pharmaceutical	NOUN
biomedich-761	235	5	sciences	sciences	PROPN
biomedich-761	235	6	and	and	CCONJ
biomedich-761	235	7	drug	drug	NOUN
biomedich-761	235	8	research	research	NOUN
biomedich-761	235	9	,	,	PUNCT
biomedich-761	235	10	223–228	223–228	NUM
biomedich-761	235	11	.	.	PUNCT
biomedich-761	236	1	https://doi.org/10.25004/ijpsdr.2016.080406	https://doi.org/10.25004/ijpsdr.2016.080406	PROPN
biomedich-761	236	2	wdowiak	wdowiak	PROPN
biomedich-761	236	3	,	,	PUNCT
biomedich-761	236	4	k.	k.	PROPN
biomedich-761	236	5	,	,	PUNCT
biomedich-761	236	6	tajber	tajber	PROPN
biomedich-761	236	7	,	,	PUNCT
biomedich-761	236	8	l.	l.	PROPN
biomedich-761	236	9	,	,	PUNCT
biomedich-761	236	10	miklaszewski	miklaszewski	PROPN
biomedich-761	236	11	,	,	PUNCT
biomedich-761	236	12	a.	a.	PROPN
biomedich-761	236	13	,	,	PUNCT
biomedich-761	236	14	&	&	CCONJ
biomedich-761	236	15	cielecka‐piontek	cielecka‐piontek	PROPN
biomedich-761	236	16	,	,	PUNCT
biomedich-761	236	17	j.	j.	PROPN
biomedich-761	236	18	(	(	PUNCT
biomedich-761	236	19	2024	2024	NUM
biomedich-761	236	20	)	)	PUNCT
biomedich-761	236	21	.	.	PUNCT
biomedich-761	237	1	application	application	NOUN
biomedich-761	237	2	of	of	ADP
biomedich-761	237	3	the	the	DET
biomedich-761	237	4	box	box	NOUN
biomedich-761	237	5	–	–	PUNCT
biomedich-761	237	6	behnken	behnken	ADJ
biomedich-761	237	7	design	design	NOUN
biomedich-761	237	8	in	in	ADP
biomedich-761	237	9	the	the	DET
biomedich-761	237	10	development	development	NOUN
biomedich-761	237	11	of	of	ADP
biomedich-761	237	12	amorphous	amorphous	ADJ
biomedich-761	237	13	pvp	pvp	NOUN
biomedich-761	237	14	k30	k30	NOUN
biomedich-761	237	15	–	–	PUNCT
biomedich-761	237	16	phosphatidylcholine	phosphatidylcholine	NOUN
biomedich-761	237	17	dispersions	dispersion	NOUN
biomedich-761	237	18	for	for	ADP
biomedich-761	237	19	the	the	DET
biomedich-761	237	20	co	co	NOUN
biomedich-761	237	21	-	-	NOUN
biomedich-761	237	22	delivery	delivery	NOUN
biomedich-761	237	23	of	of	ADP
biomedich-761	237	24	curcumin	curcumin	NOUN
biomedich-761	237	25	and	and	CCONJ
biomedich-761	237	26	hesperetin	hesperetin	NOUN
biomedich-761	237	27	prepared	prepare	VERB
biomedich-761	237	28	by	by	ADP
biomedich-761	237	29	hot	hot	ADJ
biomedich-761	237	30	-	-	PUNCT
biomedich-761	237	31	melt	melt	NOUN
biomedich-761	237	32	extrusion	extrusion	NOUN
biomedich-761	237	33	.	.	PUNCT
biomedich-761	238	1	pharmaceutics	pharmaceutic	NOUN
biomedich-761	238	2	,	,	PUNCT
biomedich-761	238	3	17(1	17(1	NUM
biomedich-761	238	4	)	)	PUNCT
biomedich-761	238	5	,	,	PUNCT
biomedich-761	238	6	26	26	NUM
biomedich-761	238	7	.	.	PUNCT
biomedich-761	239	1	https://doi.org/10.3390/pharmaceutics17010026	https://doi.org/10.3390/pharmaceutics17010026	PROPN
biomedich-761	239	2	wicaksono	wicaksono	PROPN
biomedich-761	239	3	,	,	PUNCT
biomedich-761	239	4	y.	y.	PROPN
biomedich-761	239	5	,	,	PUNCT
biomedich-761	239	6	setyawan	setyawan	NOUN
biomedich-761	239	7	,	,	PUNCT
biomedich-761	239	8	d.	d.	PROPN
biomedich-761	239	9	,	,	PUNCT
biomedich-761	239	10	siswandono	siswandono	PROPN
biomedich-761	239	11	,	,	PUNCT
biomedich-761	239	12	s.	s.	PROPN
biomedich-761	239	13	,	,	PUNCT
biomedich-761	239	14	&	&	CCONJ
biomedich-761	239	15	siswoyo	siswoyo	PROPN
biomedich-761	239	16	,	,	PUNCT
biomedich-761	239	17	t.	t.	NOUN
biomedich-761	239	18	a.	a.	NOUN
biomedich-761	239	19	(	(	PUNCT
biomedich-761	239	20	2019	2019	NUM
biomedich-761	239	21	)	)	PUNCT
biomedich-761	239	22	.	.	PUNCT
biomedich-761	240	1	preparation	preparation	NOUN
biomedich-761	240	2	and	and	CCONJ
biomedich-761	240	3	characterization	characterization	NOUN
biomedich-761	240	4	of	of	ADP
biomedich-761	240	5	a	a	DET
biomedich-761	240	6	novel	novel	ADJ
biomedich-761	240	7	cocrystal	cocrystal	NOUN
biomedich-761	240	8	of	of	ADP
biomedich-761	240	9	atorvastatin	atorvastatin	PROPN
biomedich-761	240	10	calcium	calcium	NOUN
biomedich-761	240	11	with	with	ADP
biomedich-761	240	12	succinic	succinic	ADJ
biomedich-761	240	13	acid	acid	NOUN
biomedich-761	240	14	coformer	coformer	NOUN
biomedich-761	240	15	.	.	PUNCT
biomedich-761	241	1	indonesian	indonesian	ADJ
biomedich-761	241	2	journal	journal	PROPN
biomedich-761	241	3	of	of	ADP
biomedich-761	241	4	chemistry	chemistry	NOUN
biomedich-761	241	5	,	,	PUNCT
biomedich-761	241	6	19(3	19(3	NUM
biomedich-761	241	7	)	)	PUNCT
biomedich-761	241	8	,	,	PUNCT
biomedich-761	241	9	660	660	NUM
biomedich-761	241	10	.	.	PUNCT
biomedich-761	242	1	https://doi.org/10.22146/ijc.35801	https://doi.org/10.22146/ijc.35801	NOUN
biomedich-761	242	2	this	this	DET
biomedich-761	242	3	page	page	NOUN
biomedich-761	242	4	intentionally	intentionally	ADV
biomedich-761	242	5	left	leave	VERB
biomedich-761	242	6	blank	blank	ADV