id	sid	tid	token	lemma	pos
biomedich-899	1	1	biology	biology	NOUN
biomedich-899	1	2	,	,	PUNCT
biomedich-899	1	3	medicine	medicine	NOUN
biomedich-899	1	4	,	,	PUNCT
biomedich-899	1	5	&	&	CCONJ
biomedich-899	1	6	natural	natural	ADJ
biomedich-899	1	7	product	product	NOUN
biomedich-899	1	8	chemistry	chemistry	NOUN
biomedich-899	1	9	issn	issn	VERB
biomedich-899	1	10	2089	2089	NUM
biomedich-899	1	11	-	-	SYM
biomedich-899	1	12	6514	6514	NUM
biomedich-899	1	13	(	(	PUNCT
biomedich-899	1	14	paper	paper	NOUN
biomedich-899	1	15	)	)	PUNCT
biomedich-899	1	16	volume	volume	NOUN
biomedich-899	1	17	14	14	NUM
biomedich-899	1	18	,	,	PUNCT
biomedich-899	1	19	number	number	NOUN
biomedich-899	1	20	2	2	NUM
biomedich-899	1	21	,	,	PUNCT
biomedich-899	1	22	october	october	PROPN
biomedich-899	1	23	2025	2025	NUM
biomedich-899	1	24	|	|	ADV
biomedich-899	1	25	pages	page	NOUN
biomedich-899	1	26	:	:	PUNCT
biomedich-899	1	27	905	905	NUM
biomedich-899	1	28	-	-	SYM
biomedich-899	1	29	909	909	NUM
biomedich-899	1	30	|	|	ADV
biomedich-899	1	31	doi	doi	NOUN
biomedich-899	1	32	:	:	PUNCT
biomedich-899	1	33	10.14421	10.14421	NUM
biomedich-899	1	34	/	/	SYM
biomedich-899	1	35	biomedich.2025.142.905	biomedich.2025.142.905	VERB
biomedich-899	1	36	-	-	PUNCT
biomedich-899	1	37	909	909	NUM
biomedich-899	1	38	issn	issn	PROPN
biomedich-899	1	39	2540	2540	NUM
biomedich-899	1	40	-	-	SYM
biomedich-899	1	41	9328	9328	NUM
biomedich-899	1	42	(	(	PUNCT
biomedich-899	1	43	online	online	ADJ
biomedich-899	1	44	)	)	PUNCT
biomedich-899	1	45	synthesis	synthesis	NOUN
biomedich-899	1	46	,	,	PUNCT
biomedich-899	1	47	characterization	characterization	NOUN
biomedich-899	1	48	,	,	PUNCT
biomedich-899	1	49	and	and	CCONJ
biomedich-899	1	50	micellar	micellar	ADJ
biomedich-899	1	51	behavior	behavior	NOUN
biomedich-899	1	52	of	of	ADP
biomedich-899	1	53	amphiphilic	amphiphilic	ADJ
biomedich-899	1	54	chitosan	chitosan	NOUN
biomedich-899	1	55	bearing	bearing	NOUN
biomedich-899	1	56	sulfate	sulfate	NOUN
biomedich-899	1	57	and	and	CCONJ
biomedich-899	1	58	anisaldehyde	anisaldehyde	VERB
biomedich-899	1	59	imine	imine	ADJ
biomedich-899	1	60	groups	group	NOUN
biomedich-899	1	61	herayati1	herayati1	PROPN
biomedich-899	1	62	*	*	PROPN
biomedich-899	1	63	,	,	PUNCT
biomedich-899	1	64	deana	deana	PROPN
biomedich-899	1	65	wahyuningrum2	wahyuningrum2	PROPN
biomedich-899	1	66	,	,	PUNCT
biomedich-899	1	67	damar	damar	PROPN
biomedich-899	1	68	nurwahyu	nurwahyu	PROPN
biomedich-899	1	69	bima3	bima3	PROPN
biomedich-899	1	70	,	,	PUNCT
biomedich-899	1	71	indah	indah	PROPN
biomedich-899	1	72	puspita	puspita	PROPN
biomedich-899	1	73	sari1	sari1	PROPN
biomedich-899	2	1	1department	1department	NUM
biomedich-899	2	2	of	of	ADP
biomedich-899	2	3	cosmetic	cosmetic	ADJ
biomedich-899	2	4	engineering	engineering	NOUN
biomedich-899	2	5	,	,	PUNCT
biomedich-899	2	6	faculty	faculty	NOUN
biomedich-899	2	7	of	of	ADP
biomedich-899	2	8	industrial	industrial	ADJ
biomedich-899	2	9	technology	technology	NOUN
biomedich-899	2	10	,	,	PUNCT
biomedich-899	2	11	institut	institut	PROPN
biomedich-899	2	12	teknologi	teknologi	PROPN
biomedich-899	2	13	sumatera	sumatera	PROPN
biomedich-899	2	14	,	,	PUNCT
biomedich-899	3	1	jl	jl	PROPN
biomedich-899	3	2	.	.	PROPN
biomedich-899	3	3	terusan	terusan	PROPN
biomedich-899	3	4	ryacudu	ryacudu	NOUN
biomedich-899	3	5	,	,	PUNCT
biomedich-899	3	6	way	way	ADV
biomedich-899	3	7	huwi	huwi	ADJ
biomedich-899	3	8	,	,	PUNCT
biomedich-899	3	9	lampung	lampung	NOUN
biomedich-899	3	10	,	,	PUNCT
biomedich-899	3	11	35365	35365	NUM
biomedich-899	3	12	,	,	PUNCT
biomedich-899	3	13	indonesia	indonesia	PROPN
biomedich-899	3	14	.	.	PUNCT
biomedich-899	4	1	2organic	2organic	NUM
biomedich-899	4	2	chemistry	chemistry	NOUN
biomedich-899	4	3	research	research	NOUN
biomedich-899	4	4	group	group	NOUN
biomedich-899	4	5	,	,	PUNCT
biomedich-899	4	6	institut	institut	PROPN
biomedich-899	4	7	teknologi	teknologi	PROPN
biomedich-899	4	8	bandung	bandung	PROPN
biomedich-899	4	9	,	,	PUNCT
biomedich-899	4	10	jl	jl	PROPN
biomedich-899	4	11	.	.	PUNCT
biomedich-899	5	1	ganesha	ganesha	PROPN
biomedich-899	5	2	10	10	NUM
biomedich-899	5	3	,	,	PUNCT
biomedich-899	5	4	bandung	bandung	NOUN
biomedich-899	5	5	,	,	PUNCT
biomedich-899	5	6	40132	40132	NUM
biomedich-899	5	7	,	,	PUNCT
biomedich-899	5	8	indonesia	indonesia	PROPN
biomedich-899	5	9	.	.	PUNCT
biomedich-899	6	1	3department	3department	NUM
biomedich-899	6	2	of	of	ADP
biomedich-899	6	3	chemistry	chemistry	NOUN
biomedich-899	6	4	,	,	PUNCT
biomedich-899	6	5	diponegoro	diponegoro	PROPN
biomedich-899	6	6	university	university	PROPN
biomedich-899	6	7	,	,	PUNCT
biomedich-899	6	8	tembalang	tembalang	PROPN
biomedich-899	6	9	,	,	PUNCT
biomedich-899	6	10	semarang	semarang	PROPN
biomedich-899	6	11	,	,	PUNCT
biomedich-899	6	12	50275	50275	NUM
biomedich-899	6	13	,	,	PUNCT
biomedich-899	6	14	indonesia	indonesia	PROPN
biomedich-899	6	15	.	.	PUNCT
biomedich-899	7	1	corresponding	correspond	VERB
biomedich-899	7	2	author	author	NOUN
biomedich-899	7	3	*	*	PUNCT
biomedich-899	7	4	herayati@km.itera.ac.id	herayati@km.itera.ac.id	NOUN
biomedich-899	7	5	manuscript	manuscript	NOUN
biomedich-899	7	6	received	receive	VERB
biomedich-899	7	7	:	:	PUNCT
biomedich-899	7	8	05	05	NUM
biomedich-899	7	9	august	august	NOUN
biomedich-899	7	10	,	,	PUNCT
biomedich-899	7	11	2025	2025	NUM
biomedich-899	7	12	.	.	PUNCT
biomedich-899	8	1	revision	revision	NOUN
biomedich-899	8	2	accepted	accept	VERB
biomedich-899	8	3	:	:	PUNCT
biomedich-899	8	4	14	14	NUM
biomedich-899	8	5	october	october	PROPN
biomedich-899	8	6	,	,	PUNCT
biomedich-899	8	7	2025	2025	NUM
biomedich-899	8	8	.	.	PUNCT
biomedich-899	9	1	published	publish	VERB
biomedich-899	9	2	:	:	PUNCT
biomedich-899	9	3	24	24	NUM
biomedich-899	9	4	october	october	PROPN
biomedich-899	9	5	,	,	PUNCT
biomedich-899	9	6	2025	2025	NUM
biomedich-899	9	7	.	.	PUNCT
biomedich-899	10	1	abstract	abstract	ADJ
biomedich-899	10	2	amphiphilic	amphiphilic	ADJ
biomedich-899	10	3	chitosan	chitosan	NOUN
biomedich-899	10	4	derivatives	derivative	NOUN
biomedich-899	10	5	bearing	bear	VERB
biomedich-899	10	6	sulfate	sulfate	NOUN
biomedich-899	10	7	and	and	CCONJ
biomedich-899	10	8	anisaldehyde	anisaldehyde	NOUN
biomedich-899	10	9	imine	imine	NOUN
biomedich-899	10	10	(	(	PUNCT
biomedich-899	10	11	anisimine	anisimine	NOUN
biomedich-899	10	12	)	)	PUNCT
biomedich-899	10	13	groups	group	NOUN
biomedich-899	10	14	were	be	AUX
biomedich-899	10	15	successfully	successfully	ADV
biomedich-899	10	16	synthesized	synthesize	VERB
biomedich-899	10	17	and	and	CCONJ
biomedich-899	10	18	characterized	characterize	VERB
biomedich-899	10	19	for	for	ADP
biomedich-899	10	20	potential	potential	ADJ
biomedich-899	10	21	applications	application	NOUN
biomedich-899	10	22	as	as	ADP
biomedich-899	10	23	functional	functional	ADJ
biomedich-899	10	24	biomaterials	biomaterial	NOUN
biomedich-899	10	25	.	.	PUNCT
biomedich-899	11	1	the	the	DET
biomedich-899	11	2	synthesis	synthesis	NOUN
biomedich-899	11	3	involved	involve	VERB
biomedich-899	11	4	two	two	NUM
biomedich-899	11	5	key	key	ADJ
biomedich-899	11	6	steps	step	NOUN
biomedich-899	11	7	:	:	PUNCT
biomedich-899	11	8	(	(	PUNCT
biomedich-899	11	9	1	1	X
biomedich-899	11	10	)	)	PUNCT
biomedich-899	11	11	sulfation	sulfation	NOUN
biomedich-899	11	12	of	of	ADP
biomedich-899	11	13	chitosan	chitosan	NOUN
biomedich-899	11	14	using	use	VERB
biomedich-899	11	15	chlorosulfonic	chlorosulfonic	ADJ
biomedich-899	11	16	acid	acid	NOUN
biomedich-899	11	17	to	to	PART
biomedich-899	11	18	introduce	introduce	VERB
biomedich-899	11	19	o	o	ADJ
biomedich-899	11	20	-	-	ADJ
biomedich-899	11	21	sulfate	sulfate	ADJ
biomedich-899	11	22	groups	group	NOUN
biomedich-899	11	23	,	,	PUNCT
biomedich-899	11	24	and	and	CCONJ
biomedich-899	11	25	(	(	PUNCT
biomedich-899	11	26	2	2	X
biomedich-899	11	27	)	)	PUNCT
biomedich-899	11	28	schiff	schiff	NOUN
biomedich-899	11	29	base	base	NOUN
biomedich-899	11	30	formation	formation	NOUN
biomedich-899	11	31	via	via	ADP
biomedich-899	11	32	reaction	reaction	NOUN
biomedich-899	11	33	with	with	ADP
biomedich-899	11	34	p	p	NOUN
biomedich-899	11	35	-	-	PUNCT
biomedich-899	11	36	anisaldehyde	anisaldehyde	NOUN
biomedich-899	11	37	to	to	PART
biomedich-899	11	38	generate	generate	VERB
biomedich-899	11	39	n	n	CCONJ
biomedich-899	11	40	-	-	PUNCT
biomedich-899	11	41	anisimine	anisimine	NOUN
biomedich-899	11	42	functionalities	functionality	NOUN
biomedich-899	11	43	.	.	PUNCT
biomedich-899	12	1	structural	structural	ADJ
biomedich-899	12	2	modifications	modification	NOUN
biomedich-899	12	3	were	be	AUX
biomedich-899	12	4	confirmed	confirm	VERB
biomedich-899	12	5	by	by	ADP
biomedich-899	12	6	fourier	fourier	NOUN
biomedich-899	12	7	-	-	PUNCT
biomedich-899	12	8	transform	transform	NOUN
biomedich-899	12	9	infrared	infrared	NOUN
biomedich-899	12	10	(	(	PUNCT
biomedich-899	12	11	ftir	ftir	NOUN
biomedich-899	12	12	)	)	PUNCT
biomedich-899	12	13	spectroscopy	spectroscopy	NOUN
biomedich-899	12	14	,	,	PUNCT
biomedich-899	12	15	which	which	PRON
biomedich-899	12	16	showed	show	VERB
biomedich-899	12	17	characteristic	characteristic	ADJ
biomedich-899	12	18	absorption	absorption	NOUN
biomedich-899	12	19	bands	band	NOUN
biomedich-899	12	20	at	at	ADP
biomedich-899	12	21	~1250	~1250	NUM
biomedich-899	12	22	cm⁻¹	cm⁻¹	NOUN
biomedich-899	12	23	and	and	CCONJ
biomedich-899	12	24	~820	~820	NOUN
biomedich-899	12	25	cm⁻¹	cm⁻¹	NOUN
biomedich-899	12	26	corresponding	corresponding	NOUN
biomedich-899	12	27	to	to	ADP
biomedich-899	12	28	o	o	NOUN
biomedich-899	12	29	=	=	SYM
biomedich-899	12	30	s	s	NOUN
biomedich-899	12	31	=	=	NOUN
biomedich-899	12	32	o	o	NOUN
biomedich-899	12	33	stretching	stretching	NOUN
biomedich-899	12	34	of	of	ADP
biomedich-899	12	35	sulfate	sulfate	NOUN
biomedich-899	12	36	,	,	PUNCT
biomedich-899	12	37	and	and	CCONJ
biomedich-899	12	38	a	a	DET
biomedich-899	12	39	c	c	NOUN
biomedich-899	12	40	=	=	NOUN
biomedich-899	12	41	n	n	PRON
biomedich-899	12	42	stretch	stretch	VERB
biomedich-899	12	43	at	at	ADP
biomedich-899	12	44	~1640	~1640	NUM
biomedich-899	12	45	cm⁻¹	cm⁻¹	NOUN
biomedich-899	12	46	indicating	indicate	VERB
biomedich-899	12	47	imine	imine	ADJ
biomedich-899	12	48	formation	formation	NOUN
biomedich-899	12	49	.	.	PUNCT
biomedich-899	13	1	proton	proton	NOUN
biomedich-899	13	2	nuclear	nuclear	PROPN
biomedich-899	13	3	magnetic	magnetic	ADJ
biomedich-899	13	4	resonance	resonance	NOUN
biomedich-899	13	5	(	(	PUNCT
biomedich-899	13	6	1h	1h	NUM
biomedich-899	13	7	-	-	PUNCT
biomedich-899	13	8	nmr	nmr	NOUN
biomedich-899	13	9	)	)	PUNCT
biomedich-899	13	10	spectra	spectra	NOUN
biomedich-899	13	11	further	far	ADV
biomedich-899	13	12	verified	verify	VERB
biomedich-899	13	13	the	the	DET
biomedich-899	13	14	successful	successful	ADJ
biomedich-899	13	15	attachment	attachment	NOUN
biomedich-899	13	16	of	of	ADP
biomedich-899	13	17	aromatic	aromatic	ADJ
biomedich-899	13	18	protons	proton	NOUN
biomedich-899	13	19	from	from	ADP
biomedich-899	13	20	p	p	NOUN
biomedich-899	13	21	-	-	PUNCT
biomedich-899	13	22	anisaldehyde	anisaldehyde	NOUN
biomedich-899	13	23	and	and	CCONJ
biomedich-899	13	24	the	the	DET
biomedich-899	13	25	disappearance	disappearance	NOUN
biomedich-899	13	26	of	of	ADP
biomedich-899	13	27	primary	primary	ADJ
biomedich-899	13	28	amine	amine	ADJ
biomedich-899	13	29	peaks	peak	NOUN
biomedich-899	13	30	,	,	PUNCT
biomedich-899	13	31	confirming	confirm	VERB
biomedich-899	13	32	imination	imination	NOUN
biomedich-899	13	33	.	.	PUNCT
biomedich-899	14	1	the	the	DET
biomedich-899	14	2	amphiphilic	amphiphilic	ADJ
biomedich-899	14	3	behavior	behavior	NOUN
biomedich-899	14	4	and	and	CCONJ
biomedich-899	14	5	micelle	micelle	NOUN
biomedich-899	14	6	-	-	PUNCT
biomedich-899	14	7	forming	form	VERB
biomedich-899	14	8	ability	ability	NOUN
biomedich-899	14	9	of	of	ADP
biomedich-899	14	10	the	the	DET
biomedich-899	14	11	n	n	CCONJ
biomedich-899	14	12	-	-	PUNCT
biomedich-899	14	13	anisimine	anisimine	NOUN
biomedich-899	14	14	-	-	PUNCT
biomedich-899	14	15	o	o	NOUN
biomedich-899	14	16	-	-	ADJ
biomedich-899	14	17	sulfated	sulfated	ADJ
biomedich-899	14	18	(	(	PUNCT
biomedich-899	14	19	naos	naos	PROPN
biomedich-899	14	20	)	)	PUNCT
biomedich-899	14	21	chitosan	chitosan	PROPN
biomedich-899	14	22	were	be	AUX
biomedich-899	14	23	evaluated	evaluate	VERB
biomedich-899	14	24	using	use	VERB
biomedich-899	14	25	pyrene	pyrene	NOUN
biomedich-899	14	26	as	as	ADP
biomedich-899	14	27	a	a	DET
biomedich-899	14	28	hydrophobic	hydrophobic	NOUN
biomedich-899	14	29	fluorescent	fluorescent	NOUN
biomedich-899	14	30	probe	probe	NOUN
biomedich-899	14	31	for	for	ADP
biomedich-899	14	32	determining	determine	VERB
biomedich-899	14	33	the	the	DET
biomedich-899	14	34	critical	critical	ADJ
biomedich-899	14	35	micelle	micelle	NOUN
biomedich-899	14	36	concentration	concentration	NOUN
biomedich-899	14	37	(	(	PUNCT
biomedich-899	14	38	cmc	cmc	PROPN
biomedich-899	14	39	)	)	PUNCT
biomedich-899	14	40	,	,	PUNCT
biomedich-899	14	41	which	which	PRON
biomedich-899	14	42	was	be	AUX
biomedich-899	14	43	found	find	VERB
biomedich-899	14	44	to	to	PART
biomedich-899	14	45	be	be	AUX
biomedich-899	14	46	0.012	0.012	NUM
biomedich-899	14	47	mg	mg	NUM
biomedich-899	14	48	/	/	SYM
biomedich-899	14	49	ml	ml	NOUN
biomedich-899	14	50	.	.	PUNCT
biomedich-899	15	1	the	the	DET
biomedich-899	15	2	observed	observe	VERB
biomedich-899	15	3	low	low	ADJ
biomedich-899	15	4	cmc	cmc	NOUN
biomedich-899	15	5	value	value	NOUN
biomedich-899	15	6	indicates	indicate	VERB
biomedich-899	15	7	strong	strong	ADJ
biomedich-899	15	8	selfassembly	selfassembly	ADJ
biomedich-899	15	9	capability	capability	NOUN
biomedich-899	15	10	in	in	ADP
biomedich-899	15	11	aqueous	aqueous	ADJ
biomedich-899	15	12	media	medium	NOUN
biomedich-899	15	13	.	.	PUNCT
biomedich-899	16	1	these	these	DET
biomedich-899	16	2	results	result	NOUN
biomedich-899	16	3	suggest	suggest	VERB
biomedich-899	16	4	that	that	SCONJ
biomedich-899	16	5	naos	naos	PROPN
biomedich-899	16	6	chitosan	chitosan	PROPN
biomedich-899	16	7	possesses	possess	VERB
biomedich-899	16	8	promising	promise	VERB
biomedich-899	16	9	structural	structural	ADJ
biomedich-899	16	10	and	and	CCONJ
biomedich-899	16	11	surface	surface	NOUN
biomedich-899	16	12	-	-	PUNCT
biomedich-899	16	13	active	active	ADJ
biomedich-899	16	14	properties	property	NOUN
biomedich-899	16	15	suitable	suitable	ADJ
biomedich-899	16	16	for	for	ADP
biomedich-899	16	17	advanced	advanced	ADJ
biomedich-899	16	18	applications	application	NOUN
biomedich-899	16	19	in	in	ADP
biomedich-899	16	20	drug	drug	NOUN
biomedich-899	16	21	delivery	delivery	NOUN
biomedich-899	16	22	and	and	CCONJ
biomedich-899	16	23	cosmetic	cosmetic	NOUN
biomedich-899	16	24	formulations	formulation	NOUN
biomedich-899	16	25	.	.	PUNCT
biomedich-899	17	1	keywords	keyword	NOUN
biomedich-899	17	2	:	:	PUNCT
biomedich-899	17	3	amphiphilic	amphiphilic	ADJ
biomedich-899	17	4	polymers	polymer	NOUN
biomedich-899	17	5	;	;	PUNCT
biomedich-899	17	6	chitosan	chitosan	NOUN
biomedich-899	17	7	derivatives	derivative	NOUN
biomedich-899	17	8	;	;	PUNCT
biomedich-899	17	9	delivery	delivery	NOUN
biomedich-899	17	10	systems	system	NOUN
biomedich-899	17	11	;	;	PUNCT
biomedich-899	17	12	schiff	schiff	NOUN
biomedich-899	17	13	base	base	NOUN
biomedich-899	17	14	.	.	PUNCT
biomedich-899	18	1	introduction	introduction	NOUN
biomedich-899	18	2	chitosan	chitosan	NOUN
biomedich-899	18	3	,	,	PUNCT
biomedich-899	18	4	a	a	DET
biomedich-899	18	5	natural	natural	ADJ
biomedich-899	18	6	polysaccharide	polysaccharide	NOUN
biomedich-899	18	7	derived	derive	VERB
biomedich-899	18	8	from	from	ADP
biomedich-899	18	9	chitin	chitin	NOUN
biomedich-899	18	10	,	,	PUNCT
biomedich-899	18	11	has	have	AUX
biomedich-899	18	12	garnered	garner	VERB
biomedich-899	18	13	significant	significant	ADJ
biomedich-899	18	14	attention	attention	NOUN
biomedich-899	18	15	due	due	ADP
biomedich-899	18	16	to	to	ADP
biomedich-899	18	17	its	its	PRON
biomedich-899	18	18	biocompatibility	biocompatibility	NOUN
biomedich-899	18	19	,	,	PUNCT
biomedich-899	18	20	biodegradability	biodegradability	NOUN
biomedich-899	18	21	,	,	PUNCT
biomedich-899	18	22	and	and	CCONJ
biomedich-899	18	23	versatile	versatile	ADJ
biomedich-899	18	24	chemical	chemical	ADJ
biomedich-899	18	25	functionality	functionality	NOUN
biomedich-899	18	26	.	.	PUNCT
biomedich-899	19	1	its	its	PRON
biomedich-899	19	2	primary	primary	ADJ
biomedich-899	19	3	amino	amino	NOUN
biomedich-899	19	4	and	and	CCONJ
biomedich-899	19	5	hydroxyl	hydroxyl	NOUN
biomedich-899	19	6	groups	group	NOUN
biomedich-899	19	7	offer	offer	VERB
biomedich-899	19	8	extensive	extensive	ADJ
biomedich-899	19	9	opportunities	opportunity	NOUN
biomedich-899	19	10	for	for	ADP
biomedich-899	19	11	chemical	chemical	ADJ
biomedich-899	19	12	modifications	modification	NOUN
biomedich-899	19	13	,	,	PUNCT
biomedich-899	19	14	enabling	enable	VERB
biomedich-899	19	15	the	the	DET
biomedich-899	19	16	development	development	NOUN
biomedich-899	19	17	of	of	ADP
biomedich-899	19	18	tailored	tailor	VERB
biomedich-899	19	19	materials	material	NOUN
biomedich-899	19	20	for	for	ADP
biomedich-899	19	21	applications	application	NOUN
biomedich-899	19	22	in	in	ADP
biomedich-899	19	23	drug	drug	NOUN
biomedich-899	19	24	delivery	delivery	NOUN
biomedich-899	19	25	,	,	PUNCT
biomedich-899	19	26	cosmetics	cosmetic	NOUN
biomedich-899	19	27	,	,	PUNCT
biomedich-899	19	28	and	and	CCONJ
biomedich-899	19	29	tissue	tissue	NOUN
biomedich-899	19	30	engineering	engineering	NOUN
biomedich-899	19	31	.	.	PUNCT
biomedich-899	20	1	however	however	ADV
biomedich-899	20	2	,	,	PUNCT
biomedich-899	20	3	the	the	DET
biomedich-899	20	4	inherent	inherent	ADJ
biomedich-899	20	5	hydrophilicity	hydrophilicity	NOUN
biomedich-899	20	6	of	of	ADP
biomedich-899	20	7	chitosan	chitosan	NOUN
biomedich-899	20	8	often	often	ADV
biomedich-899	20	9	limits	limit	VERB
biomedich-899	20	10	its	its	PRON
biomedich-899	20	11	ability	ability	NOUN
biomedich-899	20	12	to	to	PART
biomedich-899	20	13	interact	interact	VERB
biomedich-899	20	14	effectively	effectively	ADV
biomedich-899	20	15	with	with	ADP
biomedich-899	20	16	hydrophobic	hydrophobic	NOUN
biomedich-899	20	17	compounds	compound	NOUN
biomedich-899	20	18	,	,	PUNCT
biomedich-899	20	19	thereby	thereby	ADV
biomedich-899	20	20	restricting	restrict	VERB
biomedich-899	20	21	its	its	PRON
biomedich-899	20	22	use	use	NOUN
biomedich-899	20	23	in	in	ADP
biomedich-899	20	24	systems	system	NOUN
biomedich-899	20	25	that	that	PRON
biomedich-899	20	26	require	require	VERB
biomedich-899	20	27	amphiphilic	amphiphilic	ADJ
biomedich-899	20	28	properties	property	NOUN
biomedich-899	20	29	.	.	PUNCT
biomedich-899	21	1	the	the	DET
biomedich-899	21	2	introduction	introduction	NOUN
biomedich-899	21	3	of	of	ADP
biomedich-899	21	4	amphiphilic	amphiphilic	ADJ
biomedich-899	21	5	functionalities	functionality	NOUN
biomedich-899	21	6	to	to	ADP
biomedich-899	21	7	chitosan	chitosan	NOUN
biomedich-899	21	8	has	have	AUX
biomedich-899	21	9	emerged	emerge	VERB
biomedich-899	21	10	as	as	ADP
biomedich-899	21	11	a	a	DET
biomedich-899	21	12	promising	promising	ADJ
biomedich-899	21	13	strategy	strategy	NOUN
biomedich-899	21	14	to	to	PART
biomedich-899	21	15	overcome	overcome	VERB
biomedich-899	21	16	these	these	DET
biomedich-899	21	17	limitations	limitation	NOUN
biomedich-899	21	18	.	.	PUNCT
biomedich-899	22	1	amphiphilic	amphiphilic	ADJ
biomedich-899	22	2	chitosan	chitosan	NOUN
biomedich-899	22	3	derivatives	derivative	NOUN
biomedich-899	22	4	,	,	PUNCT
biomedich-899	22	5	capable	capable	ADJ
biomedich-899	22	6	of	of	ADP
biomedich-899	22	7	forming	form	VERB
biomedich-899	22	8	self	self	NOUN
biomedich-899	22	9	-	-	PUNCT
biomedich-899	22	10	assembled	assemble	VERB
biomedich-899	22	11	structures	structure	NOUN
biomedich-899	22	12	such	such	ADJ
biomedich-899	22	13	as	as	ADP
biomedich-899	22	14	micelles	micelle	NOUN
biomedich-899	22	15	or	or	CCONJ
biomedich-899	22	16	nanoparticles	nanoparticle	NOUN
biomedich-899	22	17	,	,	PUNCT
biomedich-899	22	18	have	have	AUX
biomedich-899	22	19	been	be	AUX
biomedich-899	22	20	extensively	extensively	ADV
biomedich-899	22	21	investigated	investigate	VERB
biomedich-899	22	22	in	in	ADP
biomedich-899	22	23	recent	recent	ADJ
biomedich-899	22	24	years	year	NOUN
biomedich-899	22	25	.	.	PUNCT
biomedich-899	23	1	for	for	ADP
biomedich-899	23	2	instance	instance	NOUN
biomedich-899	23	3	,	,	PUNCT
biomedich-899	23	4	sharma	sharma	PROPN
biomedich-899	23	5	et	et	PROPN
biomedich-899	23	6	al	al	PROPN
biomedich-899	23	7	.	.	PROPN
biomedich-899	24	1	(	(	PUNCT
biomedich-899	24	2	2017	2017	NUM
biomedich-899	24	3	)	)	PUNCT
biomedich-899	24	4	synthesized	synthesize	VERB
biomedich-899	24	5	amphiphilic	amphiphilic	ADJ
biomedich-899	24	6	chitosan	chitosan	NOUN
biomedich-899	24	7	derivatives	derivative	NOUN
biomedich-899	24	8	by	by	ADP
biomedich-899	24	9	grafting	graft	VERB
biomedich-899	24	10	stearic	stearic	ADJ
biomedich-899	24	11	acid	acid	NOUN
biomedich-899	24	12	onto	onto	ADP
biomedich-899	24	13	the	the	DET
biomedich-899	24	14	chitosan	chitosan	ADJ
biomedich-899	24	15	backbone	backbone	NOUN
biomedich-899	24	16	,	,	PUNCT
biomedich-899	24	17	demonstrating	demonstrate	VERB
biomedich-899	24	18	their	their	PRON
biomedich-899	24	19	ability	ability	NOUN
biomedich-899	24	20	to	to	PART
biomedich-899	24	21	form	form	VERB
biomedich-899	24	22	nanomicelles	nanomicelle	NOUN
biomedich-899	24	23	to	to	PART
biomedich-899	24	24	deliver	deliver	VERB
biomedich-899	24	25	nonviral	nonviral	ADJ
biomedich-899	24	26	gene	gene	NOUN
biomedich-899	24	27	(	(	PUNCT
biomedich-899	24	28	sharma	sharma	PROPN
biomedich-899	24	29	&	&	CCONJ
biomedich-899	24	30	singh	singh	PROPN
biomedich-899	24	31	,	,	PUNCT
biomedich-899	24	32	2017	2017	NUM
biomedich-899	24	33	)	)	PUNCT
biomedich-899	24	34	.	.	PUNCT
biomedich-899	25	1	similarly	similarly	ADV
biomedich-899	25	2	,	,	PUNCT
biomedich-899	25	3	pol	pol	PROPN
biomedich-899	25	4	et	et	PROPN
biomedich-899	25	5	al	al	PROPN
biomedich-899	25	6	.	.	PROPN
biomedich-899	25	7	(	(	PUNCT
biomedich-899	25	8	2022	2022	NUM
biomedich-899	25	9	)	)	PUNCT
biomedich-899	25	10	reported	report	VERB
biomedich-899	25	11	the	the	DET
biomedich-899	25	12	preparation	preparation	NOUN
biomedich-899	25	13	of	of	ADP
biomedich-899	25	14	amphiphilic	amphiphilic	ADJ
biomedich-899	25	15	chitosan	chitosan	NOUN
biomedich-899	25	16	modified	modify	VERB
biomedich-899	25	17	with	with	ADP
biomedich-899	25	18	palmitoyl	palmitoyl	ADJ
biomedich-899	25	19	and	and	CCONJ
biomedich-899	25	20	quarternary	quarternary	ADJ
biomedich-899	25	21	ammonium	ammonium	NOUN
biomedich-899	25	22	moities	moitie	NOUN
biomedich-899	25	23	,	,	PUNCT
biomedich-899	25	24	demonstrating	demonstrate	VERB
biomedich-899	25	25	its	its	PRON
biomedich-899	25	26	ability	ability	NOUN
biomedich-899	25	27	to	to	PART
biomedich-899	25	28	encapsulate	encapsulate	VERB
biomedich-899	25	29	plasmid	plasmid	ADJ
biomedich-899	25	30	dna	dna	PROPN
biomedich-899	25	31	(	(	PUNCT
biomedich-899	25	32	pol	pol	NOUN
biomedich-899	25	33	et	et	PROPN
biomedich-899	25	34	al	al	PROPN
biomedich-899	25	35	.	.	PROPN
biomedich-899	25	36	,	,	PUNCT
biomedich-899	25	37	2022	2022	NUM
biomedich-899	25	38	)	)	PUNCT
biomedich-899	25	39	.	.	PUNCT
biomedich-899	26	1	in	in	ADP
biomedich-899	26	2	addition	addition	NOUN
biomedich-899	26	3	to	to	ADP
biomedich-899	26	4	hydrophobic	hydrophobic	NOUN
biomedich-899	26	5	modifications	modification	NOUN
biomedich-899	26	6	,	,	PUNCT
biomedich-899	26	7	the	the	DET
biomedich-899	26	8	introduction	introduction	NOUN
biomedich-899	26	9	of	of	ADP
biomedich-899	26	10	hydrophilic	hydrophilic	ADJ
biomedich-899	26	11	groups	group	NOUN
biomedich-899	26	12	such	such	ADJ
biomedich-899	26	13	as	as	ADP
biomedich-899	26	14	sulfate	sulfate	NOUN
biomedich-899	26	15	or	or	CCONJ
biomedich-899	26	16	carboxymethyl	carboxymethyl	NOUN
biomedich-899	26	17	functionalities	functionality	NOUN
biomedich-899	26	18	further	far	ADV
biomedich-899	26	19	enhances	enhance	VERB
biomedich-899	26	20	the	the	DET
biomedich-899	26	21	versatility	versatility	NOUN
biomedich-899	26	22	of	of	ADP
biomedich-899	26	23	chitosan	chitosan	NOUN
biomedich-899	26	24	.	.	PUNCT
biomedich-899	27	1	dimassi	dimassi	VERB
biomedich-899	27	2	et	et	PROPN
biomedich-899	27	3	al	al	PROPN
biomedich-899	27	4	.	.	PROPN
biomedich-899	28	1	(	(	PUNCT
biomedich-899	28	2	2018	2018	NUM
biomedich-899	28	3	)	)	PUNCT
biomedich-899	28	4	explored	explore	VERB
biomedich-899	28	5	sulfated	sulfate	VERB
biomedich-899	28	6	chitosan	chitosan	NOUN
biomedich-899	28	7	derivatives	derivative	NOUN
biomedich-899	28	8	and	and	CCONJ
biomedich-899	28	9	highlighted	highlight	VERB
biomedich-899	28	10	their	their	PRON
biomedich-899	28	11	improved	improved	ADJ
biomedich-899	28	12	biocompatibility	biocompatibility	NOUN
biomedich-899	28	13	and	and	CCONJ
biomedich-899	28	14	ionic	ionic	ADJ
biomedich-899	28	15	characteristics	characteristic	NOUN
biomedich-899	28	16	,	,	PUNCT
biomedich-899	28	17	making	make	VERB
biomedich-899	28	18	them	they	PRON
biomedich-899	28	19	suitable	suitable	ADJ
biomedich-899	28	20	for	for	ADP
biomedich-899	28	21	biomedical	biomedical	ADJ
biomedich-899	28	22	applications	application	NOUN
biomedich-899	28	23	(	(	PUNCT
biomedich-899	28	24	dimassi	dimassi	INTJ
biomedich-899	28	25	et	et	PROPN
biomedich-899	28	26	al	al	PROPN
biomedich-899	28	27	.	.	PROPN
biomedich-899	28	28	,	,	PUNCT
biomedich-899	28	29	2018	2018	NUM
biomedich-899	28	30	)	)	PUNCT
biomedich-899	28	31	.	.	PUNCT
biomedich-899	29	1	moreover	moreover	ADV
biomedich-899	29	2	,	,	PUNCT
biomedich-899	29	3	amphiphilic	amphiphilic	ADJ
biomedich-899	29	4	chitosan	chitosan	NOUN
biomedich-899	29	5	bearing	bear	VERB
biomedich-899	29	6	both	both	CCONJ
biomedich-899	29	7	hydrophobic	hydrophobic	NOUN
biomedich-899	29	8	and	and	CCONJ
biomedich-899	29	9	hydrophilic	hydrophilic	ADJ
biomedich-899	29	10	modifications	modification	NOUN
biomedich-899	29	11	has	have	AUX
biomedich-899	29	12	shown	show	VERB
biomedich-899	29	13	exceptional	exceptional	ADJ
biomedich-899	29	14	potential	potential	NOUN
biomedich-899	29	15	in	in	ADP
biomedich-899	29	16	forming	form	VERB
biomedich-899	29	17	stable	stable	ADJ
biomedich-899	29	18	emulsions	emulsion	NOUN
biomedich-899	29	19	and	and	CCONJ
biomedich-899	29	20	hydrogels	hydrogel	NOUN
biomedich-899	29	21	for	for	ADP
biomedich-899	29	22	cosmetic	cosmetic	ADJ
biomedich-899	29	23	and	and	CCONJ
biomedich-899	29	24	pharmaceutical	pharmaceutical	NOUN
biomedich-899	29	25	formulations	formulation	NOUN
biomedich-899	29	26	(	(	PUNCT
biomedich-899	29	27	lazaridou	lazaridou	NOUN
biomedich-899	29	28	et	et	PROPN
biomedich-899	29	29	al	al	PROPN
biomedich-899	29	30	.	.	PROPN
biomedich-899	29	31	,	,	PUNCT
biomedich-899	29	32	2025	2025	NUM
biomedich-899	29	33	)	)	PUNCT
biomedich-899	29	34	.	.	PUNCT
biomedich-899	30	1	among	among	ADP
biomedich-899	30	2	hydrophobic	hydrophobic	NOUN
biomedich-899	30	3	modifications	modification	NOUN
biomedich-899	30	4	,	,	PUNCT
biomedich-899	30	5	aromatic	aromatic	ADJ
biomedich-899	30	6	groups	group	NOUN
biomedich-899	30	7	such	such	ADJ
biomedich-899	30	8	as	as	ADP
biomedich-899	30	9	anisimine	anisimine	NOUN
biomedich-899	30	10	offer	offer	VERB
biomedich-899	30	11	unique	unique	ADJ
biomedich-899	30	12	advantages	advantage	NOUN
biomedich-899	30	13	due	due	ADP
biomedich-899	30	14	to	to	ADP
biomedich-899	30	15	their	their	PRON
biomedich-899	30	16	ability	ability	NOUN
biomedich-899	30	17	to	to	PART
biomedich-899	30	18	enhance	enhance	VERB
biomedich-899	30	19	the	the	DET
biomedich-899	30	20	interaction	interaction	NOUN
biomedich-899	30	21	of	of	ADP
biomedich-899	30	22	material	material	NOUN
biomedich-899	30	23	with	with	ADP
biomedich-899	30	24	hydrophobic	hydrophobic	NOUN
biomedich-899	30	25	drugs	drug	NOUN
biomedich-899	30	26	and	and	CCONJ
biomedich-899	30	27	aromatic	aromatic	ADJ
biomedich-899	30	28	compounds	compound	NOUN
biomedich-899	30	29	through	through	ADP
biomedich-899	30	30	π	π	PROPN
biomedich-899	30	31	-	-	PUNCT
biomedich-899	30	32	π	π	ADJ
biomedich-899	30	33	interactions	interaction	NOUN
biomedich-899	30	34	which	which	PRON
biomedich-899	30	35	is	be	AUX
biomedich-899	30	36	an	an	DET
biomedich-899	30	37	essential	essential	ADJ
biomedich-899	30	38	driving	driving	NOUN
biomedich-899	30	39	force	force	NOUN
biomedich-899	30	40	for	for	ADP
biomedich-899	30	41	selfassembly	selfassembly	ADV
biomedich-899	30	42	(	(	PUNCT
biomedich-899	30	43	gao	gao	PROPN
biomedich-899	30	44	et	et	PROPN
biomedich-899	30	45	al	al	PROPN
biomedich-899	30	46	.	.	PROPN
biomedich-899	30	47	,	,	PUNCT
biomedich-899	30	48	2023	2023	NUM
biomedich-899	30	49	)	)	PUNCT
biomedich-899	30	50	.	.	PUNCT
biomedich-899	31	1	sulfation	sulfation	NOUN
biomedich-899	31	2	,	,	PUNCT
biomedich-899	31	3	on	on	ADP
biomedich-899	31	4	the	the	DET
biomedich-899	31	5	other	other	ADJ
biomedich-899	31	6	hand	hand	NOUN
biomedich-899	31	7	,	,	PUNCT
biomedich-899	31	8	introduces	introduce	NOUN
biomedich-899	31	9	negatively	negatively	ADV
biomedich-899	31	10	charged	charge	VERB
biomedich-899	31	11	sulfate	sulfate	NOUN
biomedich-899	31	12	groups	group	NOUN
biomedich-899	31	13	that	that	SCONJ
biomedich-899	31	14	https://doi.org/10.14421/biomedich.2025.142.905-909	https://doi.org/10.14421/biomedich.2025.142.905-909	NOUN
biomedich-899	31	15	906	906	NUM
biomedich-899	31	16	biology	biology	NOUN
biomedich-899	31	17	,	,	PUNCT
biomedich-899	31	18	medicine	medicine	NOUN
biomedich-899	31	19	,	,	PUNCT
biomedich-899	31	20	&	&	CCONJ
biomedich-899	31	21	natural	natural	ADJ
biomedich-899	31	22	product	product	NOUN
biomedich-899	31	23	chemistry	chemistry	NOUN
biomedich-899	31	24	14	14	NUM
biomedich-899	31	25	(	(	PUNCT
biomedich-899	31	26	2	2	NUM
biomedich-899	31	27	)	)	PUNCT
biomedich-899	31	28	,	,	PUNCT
biomedich-899	31	29	2025	2025	NUM
biomedich-899	31	30	:	:	PUNCT
biomedich-899	31	31	905	905	NUM
biomedich-899	31	32	-	-	SYM
biomedich-899	31	33	909	909	NUM
biomedich-899	31	34	improve	improve	VERB
biomedich-899	31	35	water	water	NOUN
biomedich-899	31	36	solubility	solubility	NOUN
biomedich-899	31	37	and	and	CCONJ
biomedich-899	31	38	provide	provide	VERB
biomedich-899	31	39	ionic	ionic	ADJ
biomedich-899	31	40	functionality	functionality	NOUN
biomedich-899	31	41	.	.	PUNCT
biomedich-899	32	1	combining	combine	VERB
biomedich-899	32	2	these	these	DET
biomedich-899	32	3	modifications	modification	NOUN
biomedich-899	32	4	creates	create	VERB
biomedich-899	32	5	a	a	DET
biomedich-899	32	6	synergistic	synergistic	ADJ
biomedich-899	32	7	effect	effect	NOUN
biomedich-899	32	8	,	,	PUNCT
biomedich-899	32	9	enhancing	enhance	VERB
biomedich-899	32	10	the	the	DET
biomedich-899	32	11	amphiphilic	amphiphilic	ADJ
biomedich-899	32	12	nature	nature	NOUN
biomedich-899	32	13	of	of	ADP
biomedich-899	32	14	chitosan	chitosan	NOUN
biomedich-899	32	15	and	and	CCONJ
biomedich-899	32	16	broadening	broaden	VERB
biomedich-899	32	17	its	its	PRON
biomedich-899	32	18	application	application	NOUN
biomedich-899	32	19	potential	potential	NOUN
biomedich-899	32	20	.	.	PUNCT
biomedich-899	33	1	in	in	ADP
biomedich-899	33	2	this	this	DET
biomedich-899	33	3	study	study	NOUN
biomedich-899	33	4	,	,	PUNCT
biomedich-899	33	5	novel	novel	ADJ
biomedich-899	33	6	amphiphilic	amphiphilic	ADJ
biomedich-899	33	7	chitosan	chitosan	NOUN
biomedich-899	33	8	derivatives	derivative	NOUN
biomedich-899	33	9	functionalized	functionalize	VERB
biomedich-899	33	10	with	with	ADP
biomedich-899	33	11	anisimine	anisimine	NOUN
biomedich-899	33	12	and	and	CCONJ
biomedich-899	33	13	sulfate	sulfate	NOUN
biomedich-899	33	14	groups	group	NOUN
biomedich-899	33	15	were	be	AUX
biomedich-899	33	16	synthesized	synthesize	VERB
biomedich-899	33	17	and	and	CCONJ
biomedich-899	33	18	characterized	characterize	VERB
biomedich-899	33	19	.	.	PUNCT
biomedich-899	34	1	their	their	PRON
biomedich-899	34	2	structural	structural	ADJ
biomedich-899	34	3	features	feature	NOUN
biomedich-899	34	4	and	and	CCONJ
biomedich-899	34	5	amphiphilic	amphiphilic	ADJ
biomedich-899	34	6	properties	property	NOUN
biomedich-899	34	7	were	be	AUX
biomedich-899	34	8	thoroughly	thoroughly	ADV
biomedich-899	34	9	evaluated	evaluate	VERB
biomedich-899	34	10	.	.	PUNCT
biomedich-899	35	1	this	this	DET
biomedich-899	35	2	work	work	NOUN
biomedich-899	35	3	aims	aim	VERB
biomedich-899	35	4	to	to	PART
biomedich-899	35	5	elucidate	elucidate	VERB
biomedich-899	35	6	the	the	DET
biomedich-899	35	7	potential	potential	NOUN
biomedich-899	35	8	of	of	ADP
biomedich-899	35	9	such	such	ADJ
biomedich-899	35	10	dualfunctionalized	dualfunctionalized	ADJ
biomedich-899	35	11	chitosan	chitosan	ADJ
biomedich-899	35	12	derivatives	derivative	NOUN
biomedich-899	35	13	for	for	ADP
biomedich-899	35	14	advanced	advanced	ADJ
biomedich-899	35	15	applications	application	NOUN
biomedich-899	35	16	in	in	ADP
biomedich-899	35	17	drug	drug	NOUN
biomedich-899	35	18	or	or	CCONJ
biomedich-899	35	19	cosmetic	cosmetic	ADJ
biomedich-899	35	20	delivery	delivery	NOUN
biomedich-899	35	21	systems	system	NOUN
biomedich-899	35	22	.	.	PUNCT
biomedich-899	36	1	materials	material	NOUN
biomedich-899	36	2	and	and	CCONJ
biomedich-899	36	3	methods	method	NOUN
biomedich-899	36	4	materials	material	NOUN
biomedich-899	36	5	commercially	commercially	ADV
biomedich-899	36	6	available	available	ADJ
biomedich-899	36	7	chemicals	chemical	NOUN
biomedich-899	36	8	and	and	CCONJ
biomedich-899	36	9	solvents	solvent	NOUN
biomedich-899	36	10	from	from	ADP
biomedich-899	36	11	merck	merck	PROPN
biomedich-899	36	12	were	be	AUX
biomedich-899	36	13	utilized	utilize	VERB
biomedich-899	36	14	in	in	ADP
biomedich-899	36	15	this	this	DET
biomedich-899	36	16	research	research	NOUN
biomedich-899	36	17	for	for	ADP
biomedich-899	36	18	their	their	PRON
biomedich-899	36	19	specific	specific	ADJ
biomedich-899	36	20	roles	role	NOUN
biomedich-899	36	21	and	and	CCONJ
biomedich-899	36	22	high	high	ADJ
biomedich-899	36	23	purity	purity	NOUN
biomedich-899	36	24	.	.	PUNCT
biomedich-899	37	1	chitosan	chitosan	PROPN
biomedich-899	37	2	was	be	AUX
biomedich-899	37	3	derived	derive	VERB
biomedich-899	37	4	from	from	ADP
biomedich-899	37	5	shrimp	shrimp	NOUN
biomedich-899	37	6	shells	shell	NOUN
biomedich-899	37	7	(	(	PUNCT
biomedich-899	37	8	litopenaeus	litopenaeus	PROPN
biomedich-899	37	9	vannamei	vannamei	PROPN
biomedich-899	37	10	)	)	PUNCT
biomedich-899	37	11	.	.	PUNCT
biomedich-899	38	1	chlorosulfonic	chlorosulfonic	ADJ
biomedich-899	38	2	acid	acid	NOUN
biomedich-899	38	3	(	(	PUNCT
biomedich-899	38	4	hclso₃	hclso₃	PROPN
biomedich-899	38	5	,	,	PUNCT
biomedich-899	38	6	merck	merck	PROPN
biomedich-899	38	7	,	,	PUNCT
biomedich-899	38	8	germany	germany	PROPN
biomedich-899	38	9	)	)	PUNCT
biomedich-899	38	10	used	use	VERB
biomedich-899	38	11	as	as	ADP
biomedich-899	38	12	the	the	DET
biomedich-899	38	13	sulfonation	sulfonation	NOUN
biomedich-899	38	14	agent	agent	NOUN
biomedich-899	38	15	.	.	PUNCT
biomedich-899	39	1	anisaldehyde	anisaldehyde	NOUN
biomedich-899	39	2	(	(	PUNCT
biomedich-899	39	3	merck	merck	PROPN
biomedich-899	39	4	,	,	PUNCT
biomedich-899	39	5	germany	germany	PROPN
biomedich-899	39	6	)	)	PUNCT
biomedich-899	39	7	was	be	AUX
biomedich-899	39	8	utilized	utilize	VERB
biomedich-899	39	9	for	for	ADP
biomedich-899	39	10	synthesizing	synthesize	VERB
biomedich-899	39	11	amphiphilic	amphiphilic	ADJ
biomedich-899	39	12	chitosan	chitosan	NOUN
biomedich-899	39	13	derivatives	derivative	NOUN
biomedich-899	39	14	.	.	PUNCT
biomedich-899	40	1	additional	additional	ADJ
biomedich-899	40	2	materials	material	NOUN
biomedich-899	40	3	included	include	VERB
biomedich-899	40	4	ethanol	ethanol	NOUN
biomedich-899	40	5	(	(	PUNCT
biomedich-899	40	6	merck	merck	PROPN
biomedich-899	40	7	,	,	PUNCT
biomedich-899	40	8	germany	germany	PROPN
biomedich-899	40	9	)	)	PUNCT
biomedich-899	40	10	,	,	PUNCT
biomedich-899	40	11	glacial	glacial	ADJ
biomedich-899	40	12	acetic	acetic	ADJ
biomedich-899	40	13	acid	acid	NOUN
biomedich-899	40	14	(	(	PUNCT
biomedich-899	40	15	merck	merck	PROPN
biomedich-899	40	16	,	,	PUNCT
biomedich-899	40	17	germany	germany	PROPN
biomedich-899	40	18	)	)	PUNCT
biomedich-899	40	19	,	,	PUNCT
biomedich-899	40	20	deuterated	deuterate	VERB
biomedich-899	40	21	oxide	oxide	NOUN
biomedich-899	40	22	(	(	PUNCT
biomedich-899	40	23	merck	merck	PROPN
biomedich-899	40	24	,	,	PUNCT
biomedich-899	40	25	germany	germany	PROPN
biomedich-899	40	26	)	)	PUNCT
biomedich-899	40	27	,	,	PUNCT
biomedich-899	40	28	trifluoroacetic	trifluoroacetic	ADJ
biomedich-899	40	29	acid	acid	NOUN
biomedich-899	40	30	(	(	PUNCT
biomedich-899	40	31	acros	acros	PROPN
biomedich-899	40	32	organics	organic	NOUN
biomedich-899	40	33	,	,	PUNCT
biomedich-899	40	34	usa	usa	PROPN
biomedich-899	40	35	)	)	PUNCT
biomedich-899	40	36	,	,	PUNCT
biomedich-899	40	37	pyrene	pyrene	NOUN
biomedich-899	40	38	,	,	PUNCT
biomedich-899	40	39	dialysis	dialysis	NOUN
biomedich-899	40	40	membranes	membrane	NOUN
biomedich-899	40	41	with	with	ADP
biomedich-899	40	42	molecular	molecular	ADJ
biomedich-899	40	43	weight	weight	NOUN
biomedich-899	40	44	cutoff	cutoff	NOUN
biomedich-899	40	45	(	(	PUNCT
biomedich-899	40	46	mwco	mwco	NOUN
biomedich-899	40	47	)	)	PUNCT
biomedich-899	40	48	12,000–14,000	12,000–14,000	PROPN
biomedich-899	40	49	(	(	PUNCT
biomedich-899	40	50	sigma	sigma	PROPN
biomedich-899	40	51	-	-	PUNCT
biomedich-899	40	52	aldrich	aldrich	PROPN
biomedich-899	40	53	,	,	PUNCT
biomedich-899	40	54	usa	usa	PROPN
biomedich-899	40	55	)	)	PUNCT
biomedich-899	40	56	,	,	PUNCT
biomedich-899	40	57	and	and	CCONJ
biomedich-899	40	58	cellulose	cellulose	NOUN
biomedich-899	40	59	-	-	PUNCT
biomedich-899	40	60	acetate	acetate	NOUN
biomedich-899	40	61	membrane	membrane	NOUN
biomedich-899	40	62	filters	filter	NOUN
biomedich-899	40	63	(	(	PUNCT
biomedich-899	40	64	0.45	0.45	NUM
biomedich-899	40	65	μm	μm	NOUN
biomedich-899	40	66	,	,	PUNCT
biomedich-899	40	67	merck	merck	PROPN
biomedich-899	40	68	millipore	millipore	PROPN
biomedich-899	40	69	,	,	PUNCT
biomedich-899	40	70	ireland	ireland	PROPN
biomedich-899	40	71	)	)	PUNCT
biomedich-899	40	72	.	.	PUNCT
biomedich-899	41	1	these	these	PRON
biomedich-899	41	2	were	be	AUX
biomedich-899	41	3	used	use	VERB
biomedich-899	41	4	for	for	ADP
biomedich-899	41	5	critical	critical	ADJ
biomedich-899	41	6	micelle	micelle	NOUN
biomedich-899	41	7	concentration	concentration	NOUN
biomedich-899	41	8	determination	determination	NOUN
biomedich-899	41	9	.	.	PUNCT
biomedich-899	42	1	synthesis	synthesis	NOUN
biomedich-899	42	2	of	of	ADP
biomedich-899	42	3	chitosan	chitosan	ADJ
biomedich-899	42	4	chitosan	chitosan	NOUN
biomedich-899	42	5	was	be	AUX
biomedich-899	42	6	prepared	prepare	VERB
biomedich-899	42	7	from	from	ADP
biomedich-899	42	8	shrimp	shrimp	PROPN
biomedich-899	42	9	shell	shell	PROPN
biomedich-899	42	10	waste	waste	NOUN
biomedich-899	42	11	through	through	ADP
biomedich-899	42	12	a	a	DET
biomedich-899	42	13	multistep	multistep	ADJ
biomedich-899	42	14	chemical	chemical	NOUN
biomedich-899	42	15	process	process	NOUN
biomedich-899	42	16	involving	involve	VERB
biomedich-899	42	17	demineralization	demineralization	NOUN
biomedich-899	42	18	,	,	PUNCT
biomedich-899	42	19	deproteinization	deproteinization	NOUN
biomedich-899	42	20	,	,	PUNCT
biomedich-899	42	21	and	and	CCONJ
biomedich-899	42	22	deacetylation	deacetylation	NOUN
biomedich-899	42	23	,	,	PUNCT
biomedich-899	42	24	following	follow	VERB
biomedich-899	42	25	a	a	DET
biomedich-899	42	26	modified	modify	VERB
biomedich-899	42	27	procedure	procedure	NOUN
biomedich-899	42	28	based	base	VERB
biomedich-899	42	29	on	on	ADP
biomedich-899	42	30	zvezdova	zvezdova	PROPN
biomedich-899	42	31	(	(	PUNCT
biomedich-899	42	32	2010	2010	NUM
biomedich-899	42	33	)	)	PUNCT
biomedich-899	42	34	and	and	CCONJ
biomedich-899	42	35	suendo	suendo	PROPN
biomedich-899	42	36	et	et	PROPN
biomedich-899	42	37	al	al	PROPN
biomedich-899	42	38	.	.	PROPN
biomedich-899	43	1	(	(	PUNCT
biomedich-899	43	2	2010	2010	NUM
biomedich-899	43	3	)	)	PUNCT
biomedich-899	43	4	.	.	PUNCT
biomedich-899	44	1	initially	initially	ADV
biomedich-899	44	2	,	,	PUNCT
biomedich-899	44	3	shrimp	shrimp	NOUN
biomedich-899	44	4	shells	shell	NOUN
biomedich-899	44	5	were	be	AUX
biomedich-899	44	6	thoroughly	thoroughly	ADV
biomedich-899	44	7	cleaned	clean	VERB
biomedich-899	44	8	to	to	PART
biomedich-899	44	9	remove	remove	VERB
biomedich-899	44	10	residual	residual	ADJ
biomedich-899	44	11	organic	organic	ADJ
biomedich-899	44	12	matter	matter	NOUN
biomedich-899	44	13	,	,	PUNCT
biomedich-899	44	14	then	then	ADV
biomedich-899	44	15	washed	wash	VERB
biomedich-899	44	16	,	,	PUNCT
biomedich-899	44	17	dried	dry	VERB
biomedich-899	44	18	,	,	PUNCT
biomedich-899	44	19	and	and	CCONJ
biomedich-899	44	20	milled	mill	VERB
biomedich-899	44	21	into	into	ADP
biomedich-899	44	22	a	a	DET
biomedich-899	44	23	fine	fine	ADJ
biomedich-899	44	24	powder	powder	NOUN
biomedich-899	44	25	(	(	PUNCT
biomedich-899	44	26	particle	particle	NOUN
biomedich-899	44	27	size	size	NOUN
biomedich-899	44	28	~0.3–0.5	~0.3–0.5	NUM
biomedich-899	44	29	mm	mm	NOUN
biomedich-899	44	30	)	)	PUNCT
biomedich-899	44	31	(	(	PUNCT
biomedich-899	44	32	zvezdova	zvezdova	PROPN
biomedich-899	44	33	,	,	PUNCT
biomedich-899	44	34	2010	2010	NUM
biomedich-899	44	35	)	)	PUNCT
biomedich-899	44	36	(	(	PUNCT
biomedich-899	44	37	suendo	suendo	PROPN
biomedich-899	44	38	et	et	PROPN
biomedich-899	44	39	al	al	PROPN
biomedich-899	44	40	.	.	PROPN
biomedich-899	44	41	,	,	PUNCT
biomedich-899	44	42	2010	2010	NUM
biomedich-899	44	43	)	)	PUNCT
biomedich-899	44	44	.	.	PUNCT
biomedich-899	45	1	the	the	DET
biomedich-899	45	2	demineralization	demineralization	NOUN
biomedich-899	45	3	process	process	NOUN
biomedich-899	45	4	was	be	AUX
biomedich-899	45	5	conducted	conduct	VERB
biomedich-899	45	6	by	by	ADP
biomedich-899	45	7	soaking	soak	VERB
biomedich-899	45	8	the	the	DET
biomedich-899	45	9	powdered	powdered	ADJ
biomedich-899	45	10	shells	shell	NOUN
biomedich-899	45	11	in	in	ADP
biomedich-899	45	12	7	7	NUM
biomedich-899	45	13	%	%	NOUN
biomedich-899	45	14	hydrochloric	hydrochloric	ADJ
biomedich-899	45	15	acid	acid	NOUN
biomedich-899	45	16	(	(	PUNCT
biomedich-899	45	17	hcl	hcl	PROPN
biomedich-899	45	18	)	)	PUNCT
biomedich-899	45	19	at	at	ADP
biomedich-899	45	20	room	room	NOUN
biomedich-899	45	21	temperature	temperature	NOUN
biomedich-899	45	22	using	use	VERB
biomedich-899	45	23	a	a	DET
biomedich-899	45	24	solid	solid	ADJ
biomedich-899	45	25	-	-	PUNCT
biomedich-899	45	26	to	to	ADP
biomedich-899	45	27	-	-	PUNCT
biomedich-899	45	28	liquid	liquid	ADJ
biomedich-899	45	29	ratio	ratio	NOUN
biomedich-899	45	30	of	of	ADP
biomedich-899	45	31	1:10	1:10	NUM
biomedich-899	45	32	(	(	PUNCT
biomedich-899	45	33	w	w	NOUN
biomedich-899	45	34	/	/	SYM
biomedich-899	45	35	v	v	NOUN
biomedich-899	45	36	)	)	PUNCT
biomedich-899	45	37	for	for	ADP
biomedich-899	45	38	24	24	NUM
biomedich-899	45	39	hours	hour	NOUN
biomedich-899	45	40	to	to	PART
biomedich-899	45	41	dissolve	dissolve	VERB
biomedich-899	45	42	calcium	calcium	NOUN
biomedich-899	45	43	carbonate	carbonate	NOUN
biomedich-899	45	44	and	and	CCONJ
biomedich-899	45	45	other	other	ADJ
biomedich-899	45	46	mineral	mineral	NOUN
biomedich-899	45	47	components	component	NOUN
biomedich-899	45	48	.	.	PUNCT
biomedich-899	46	1	the	the	DET
biomedich-899	46	2	sample	sample	NOUN
biomedich-899	46	3	was	be	AUX
biomedich-899	46	4	then	then	ADV
biomedich-899	46	5	filtered	filter	VERB
biomedich-899	46	6	,	,	PUNCT
biomedich-899	46	7	washed	wash	VERB
biomedich-899	46	8	repeatedly	repeatedly	ADV
biomedich-899	46	9	with	with	ADP
biomedich-899	46	10	distilled	distil	VERB
biomedich-899	46	11	water	water	NOUN
biomedich-899	46	12	until	until	SCONJ
biomedich-899	46	13	neutral	neutral	ADJ
biomedich-899	46	14	ph	ph	NOUN
biomedich-899	46	15	was	be	AUX
biomedich-899	46	16	achieved	achieve	VERB
biomedich-899	46	17	,	,	PUNCT
biomedich-899	46	18	and	and	CCONJ
biomedich-899	46	19	subsequently	subsequently	ADV
biomedich-899	46	20	dried	dry	VERB
biomedich-899	46	21	.	.	PUNCT
biomedich-899	47	1	the	the	DET
biomedich-899	47	2	deproteinization	deproteinization	NOUN
biomedich-899	47	3	step	step	NOUN
biomedich-899	47	4	involved	involve	VERB
biomedich-899	47	5	treating	treat	VERB
biomedich-899	47	6	the	the	DET
biomedich-899	47	7	demineralized	demineralize	VERB
biomedich-899	47	8	residue	residue	NOUN
biomedich-899	47	9	with	with	ADP
biomedich-899	47	10	10	10	NUM
biomedich-899	47	11	%	%	NOUN
biomedich-899	47	12	sodium	sodium	NOUN
biomedich-899	47	13	hydroxide	hydroxide	NOUN
biomedich-899	47	14	(	(	PUNCT
biomedich-899	47	15	naoh	naoh	NOUN
biomedich-899	47	16	)	)	PUNCT
biomedich-899	47	17	at	at	ADP
biomedich-899	47	18	60	60	NUM
biomedich-899	47	19	 	 	SPACE
biomedich-899	47	20	°	°	PROPN
biomedich-899	47	21	c	c	NOUN
biomedich-899	47	22	for	for	ADP
biomedich-899	47	23	24	24	NUM
biomedich-899	47	24	hours	hour	NOUN
biomedich-899	47	25	to	to	PART
biomedich-899	47	26	remove	remove	VERB
biomedich-899	47	27	proteins	protein	NOUN
biomedich-899	47	28	.	.	PUNCT
biomedich-899	48	1	after	after	ADP
biomedich-899	48	2	thorough	thorough	ADJ
biomedich-899	48	3	washing	washing	NOUN
biomedich-899	48	4	and	and	CCONJ
biomedich-899	48	5	drying	drying	NOUN
biomedich-899	48	6	,	,	PUNCT
biomedich-899	48	7	the	the	DET
biomedich-899	48	8	resulting	result	VERB
biomedich-899	48	9	material	material	NOUN
biomedich-899	48	10	(	(	PUNCT
biomedich-899	48	11	chitin	chitin	NOUN
biomedich-899	48	12	)	)	PUNCT
biomedich-899	48	13	was	be	AUX
biomedich-899	48	14	subjected	subject	VERB
biomedich-899	48	15	to	to	ADP
biomedich-899	48	16	deacetylation	deacetylation	NOUN
biomedich-899	48	17	using	use	VERB
biomedich-899	48	18	50	50	NUM
biomedich-899	48	19	%	%	NOUN
biomedich-899	48	20	naoh	naoh	NOUN
biomedich-899	48	21	at	at	ADP
biomedich-899	48	22	60	60	NUM
biomedich-899	48	23	 	 	SPACE
biomedich-899	48	24	°	°	PROPN
biomedich-899	48	25	c	c	NOUN
biomedich-899	48	26	for	for	ADP
biomedich-899	48	27	8	8	NUM
biomedich-899	48	28	hours	hour	NOUN
biomedich-899	48	29	to	to	PART
biomedich-899	48	30	convert	convert	VERB
biomedich-899	48	31	it	it	PRON
biomedich-899	48	32	into	into	ADP
biomedich-899	48	33	chitosan	chitosan	NOUN
biomedich-899	48	34	.	.	PUNCT
biomedich-899	49	1	synthesis	synthesis	NOUN
biomedich-899	49	2	of	of	ADP
biomedich-899	49	3	chitosan	chitosan	ADJ
biomedich-899	49	4	preparation	preparation	NOUN
biomedich-899	49	5	of	of	ADP
biomedich-899	49	6	o	o	ADJ
biomedich-899	49	7	-	-	NOUN
biomedich-899	49	8	sulfate	sulfate	ADJ
biomedich-899	49	9	chitosan	chitosan	NOUN
biomedich-899	49	10	chitosan	chitosan	NOUN
biomedich-899	49	11	(	(	PUNCT
biomedich-899	49	12	1	1	NUM
biomedich-899	49	13	g	g	NOUN
biomedich-899	49	14	,	,	PUNCT
biomedich-899	49	15	degree	degree	NOUN
biomedich-899	49	16	of	of	ADP
biomedich-899	49	17	deacetylation	deacetylation	NOUN
biomedich-899	49	18	(	(	PUNCT
biomedich-899	49	19	dd	dd	NOUN
biomedich-899	49	20	)	)	PUNCT
biomedich-899	49	21	88.6	88.6	NUM
biomedich-899	49	22	%	%	NOUN
biomedich-899	49	23	,	,	PUNCT
biomedich-899	49	24	molecular	molecular	ADJ
biomedich-899	49	25	weight	weight	NOUN
biomedich-899	49	26	(	(	PUNCT
biomedich-899	49	27	mw	mw	PROPN
biomedich-899	49	28	)	)	PUNCT
biomedich-899	49	29	3300	3300	NUM
biomedich-899	49	30	kda	kda	NOUN
biomedich-899	49	31	was	be	AUX
biomedich-899	49	32	reacted	react	VERB
biomedich-899	49	33	with	with	ADP
biomedich-899	49	34	chlorosulfonic	chlorosulfonic	ADJ
biomedich-899	49	35	acid	acid	NOUN
biomedich-899	49	36	(	(	PUNCT
biomedich-899	49	37	4	4	NUM
biomedich-899	49	38	ml	ml	NOUN
biomedich-899	49	39	)	)	PUNCT
biomedich-899	49	40	in	in	ADP
biomedich-899	49	41	distilled	distil	VERB
biomedich-899	49	42	water	water	NOUN
biomedich-899	49	43	(	(	PUNCT
biomedich-899	49	44	30	30	NUM
biomedich-899	49	45	ml	ml	NOUN
biomedich-899	49	46	)	)	PUNCT
biomedich-899	49	47	at	at	ADP
biomedich-899	49	48	room	room	NOUN
biomedich-899	49	49	temperature	temperature	NOUN
biomedich-899	49	50	overnight	overnight	ADV
biomedich-899	49	51	.	.	PUNCT
biomedich-899	50	1	the	the	DET
biomedich-899	50	2	reaction	reaction	NOUN
biomedich-899	50	3	mixture	mixture	NOUN
biomedich-899	50	4	was	be	AUX
biomedich-899	50	5	neutralized	neutralize	VERB
biomedich-899	50	6	using	use	VERB
biomedich-899	50	7	a	a	DET
biomedich-899	50	8	20	20	NUM
biomedich-899	50	9	%	%	NOUN
biomedich-899	50	10	(	(	PUNCT
biomedich-899	50	11	w	w	NOUN
biomedich-899	50	12	/	/	SYM
biomedich-899	50	13	v	v	NOUN
biomedich-899	50	14	)	)	PUNCT
biomedich-899	50	15	naoh	naoh	NOUN
biomedich-899	50	16	solution	solution	NOUN
biomedich-899	50	17	to	to	PART
biomedich-899	50	18	achieve	achieve	VERB
biomedich-899	50	19	a	a	DET
biomedich-899	50	20	ph	ph	NOUN
biomedich-899	50	21	of	of	ADP
biomedich-899	50	22	7	7	NUM
biomedich-899	50	23	.	.	PUNCT
biomedich-899	51	1	the	the	DET
biomedich-899	51	2	neutralized	neutralize	VERB
biomedich-899	51	3	solution	solution	NOUN
biomedich-899	51	4	was	be	AUX
biomedich-899	51	5	dialyzed	dialyze	VERB
biomedich-899	51	6	against	against	ADP
biomedich-899	51	7	deionized	deionize	VERB
biomedich-899	51	8	water	water	NOUN
biomedich-899	51	9	using	use	VERB
biomedich-899	51	10	a	a	DET
biomedich-899	51	11	dialysis	dialysis	NOUN
biomedich-899	51	12	membrane	membrane	NOUN
biomedich-899	51	13	with	with	ADP
biomedich-899	51	14	a	a	DET
biomedich-899	51	15	molecular	molecular	ADJ
biomedich-899	51	16	weight	weight	NOUN
biomedich-899	51	17	cutoff	cutoff	NOUN
biomedich-899	51	18	(	(	PUNCT
biomedich-899	51	19	mwco	mwco	NOUN
biomedich-899	51	20	12,000–14,000	12,000–14,000	NUM
biomedich-899	51	21	)	)	PUNCT
biomedich-899	51	22	for	for	ADP
biomedich-899	51	23	two	two	NUM
biomedich-899	51	24	days	day	NOUN
biomedich-899	51	25	,	,	PUNCT
biomedich-899	51	26	followed	follow	VERB
biomedich-899	51	27	by	by	ADP
biomedich-899	51	28	lyophilization	lyophilization	NOUN
biomedich-899	51	29	an	an	DET
biomedich-899	51	30	additional	additional	ADJ
biomedich-899	51	31	two	two	NUM
biomedich-899	51	32	days	day	NOUN
biomedich-899	51	33	to	to	PART
biomedich-899	51	34	obtain	obtain	VERB
biomedich-899	51	35	a	a	DET
biomedich-899	51	36	yellow	yellow	ADJ
biomedich-899	51	37	powder	powder	NOUN
biomedich-899	51	38	.	.	PUNCT
biomedich-899	52	1	preparation	preparation	NOUN
biomedich-899	52	2	of	of	ADP
biomedich-899	52	3	n	n	X
biomedich-899	52	4	-	-	PUNCT
biomedich-899	52	5	anisimine	anisimine	NOUN
biomedich-899	52	6	-o	-o	ADJ
biomedich-899	52	7	-	-	PUNCT
biomedich-899	52	8	sulfate	sulfate	NOUN
biomedich-899	52	9	chitosan	chitosan	ADJ
biomedich-899	52	10	o	o	NOUN
biomedich-899	52	11	-	-	ADJ
biomedich-899	52	12	sulfate	sulfate	ADJ
biomedich-899	52	13	chitosan	chitosan	NOUN
biomedich-899	52	14	(	(	PUNCT
biomedich-899	52	15	0.5	0.5	NUM
biomedich-899	52	16	g	g	NOUN
biomedich-899	52	17	)	)	PUNCT
biomedich-899	52	18	was	be	AUX
biomedich-899	52	19	reacted	react	VERB
biomedich-899	52	20	with	with	ADP
biomedich-899	52	21	panisaldehyde	panisaldehyde	NOUN
biomedich-899	52	22	(	(	PUNCT
biomedich-899	52	23	30	30	NUM
biomedich-899	52	24	μl	μl	PRON
biomedich-899	52	25	)	)	PUNCT
biomedich-899	52	26	in	in	ADP
biomedich-899	52	27	dimethylformamide	dimethylformamide	NOUN
biomedich-899	52	28	(	(	PUNCT
biomedich-899	52	29	dmf	dmf	PROPN
biomedich-899	52	30	,	,	PUNCT
biomedich-899	52	31	1	1	NUM
biomedich-899	52	32	ml	ml	NOUN
biomedich-899	52	33	)	)	PUNCT
biomedich-899	52	34	at	at	ADP
biomedich-899	52	35	a	a	DET
biomedich-899	52	36	molar	molar	ADJ
biomedich-899	52	37	ratio	ratio	NOUN
biomedich-899	52	38	of	of	ADP
biomedich-899	52	39	1:1	1:1	NUM
biomedich-899	52	40	and	and	CCONJ
biomedich-899	52	41	1:3	1:3	NUM
biomedich-899	52	42	(	(	PUNCT
biomedich-899	52	43	o	o	NOUN
biomedich-899	52	44	-	-	NOUN
biomedich-899	52	45	sulfate	sulfate	ADJ
biomedich-899	52	46	chitosan	chitosan	NOUN
biomedich-899	52	47	:	:	PUNCT
biomedich-899	52	48	p	p	X
biomedich-899	52	49	-	-	PUNCT
biomedich-899	52	50	anisaldehyde	anisaldehyde	NOUN
biomedich-899	52	51	)	)	PUNCT
biomedich-899	52	52	.	.	PUNCT
biomedich-899	53	1	the	the	DET
biomedich-899	53	2	reaction	reaction	NOUN
biomedich-899	53	3	was	be	AUX
biomedich-899	53	4	carried	carry	VERB
biomedich-899	53	5	out	out	ADP
biomedich-899	53	6	at	at	ADP
biomedich-899	53	7	78	78	NUM
biomedich-899	53	8	℃	℃	PROPN
biomedich-899	53	9	for	for	ADP
biomedich-899	53	10	4	4	NUM
biomedich-899	53	11	hours	hour	NOUN
biomedich-899	53	12	.	.	PUNCT
biomedich-899	54	1	the	the	DET
biomedich-899	54	2	resulting	result	VERB
biomedich-899	54	3	heterogeneous	heterogeneous	ADJ
biomedich-899	54	4	mixture	mixture	NOUN
biomedich-899	54	5	was	be	AUX
biomedich-899	54	6	filtered	filter	VERB
biomedich-899	54	7	,	,	PUNCT
biomedich-899	54	8	and	and	CCONJ
biomedich-899	54	9	the	the	DET
biomedich-899	54	10	precipitate	precipitate	NOUN
biomedich-899	54	11	was	be	AUX
biomedich-899	54	12	washed	wash	VERB
biomedich-899	54	13	with	with	ADP
biomedich-899	54	14	methanol	methanol	NOUN
biomedich-899	54	15	.	.	PUNCT
biomedich-899	55	1	the	the	DET
biomedich-899	55	2	product	product	NOUN
biomedich-899	55	3	was	be	AUX
biomedich-899	55	4	dried	dry	VERB
biomedich-899	55	5	under	under	ADP
biomedich-899	55	6	vacuum	vacuum	NOUN
biomedich-899	55	7	at	at	ADP
biomedich-899	55	8	room	room	NOUN
biomedich-899	55	9	temperature	temperature	NOUN
biomedich-899	55	10	overnight	overnight	ADV
biomedich-899	55	11	to	to	PART
biomedich-899	55	12	yield	yield	VERB
biomedich-899	55	13	a	a	DET
biomedich-899	55	14	fine	fine	ADJ
biomedich-899	55	15	powder	powder	NOUN
biomedich-899	55	16	.	.	PUNCT
biomedich-899	56	1	structural	structural	ADJ
biomedich-899	56	2	characterization	characterization	NOUN
biomedich-899	56	3	the	the	DET
biomedich-899	56	4	chemical	chemical	NOUN
biomedich-899	56	5	structures	structure	NOUN
biomedich-899	56	6	of	of	ADP
biomedich-899	56	7	chitosan	chitosan	NOUN
biomedich-899	56	8	and	and	CCONJ
biomedich-899	56	9	its	its	PRON
biomedich-899	56	10	derivatives	derivative	NOUN
biomedich-899	56	11	were	be	AUX
biomedich-899	56	12	confirmed	confirm	VERB
biomedich-899	56	13	using	use	VERB
biomedich-899	56	14	the	the	DET
biomedich-899	56	15	following	following	ADJ
biomedich-899	56	16	methods	method	NOUN
biomedich-899	56	17	.	.	PUNCT
biomedich-899	57	1	the	the	DET
biomedich-899	57	2	chemical	chemical	ADJ
biomedich-899	57	3	structure	structure	NOUN
biomedich-899	57	4	of	of	ADP
biomedich-899	57	5	chitosan	chitosan	NOUN
biomedich-899	57	6	and	and	CCONJ
biomedich-899	57	7	chitosan	chitosan	NOUN
biomedich-899	57	8	derivatives	derivative	NOUN
biomedich-899	57	9	was	be	AUX
biomedich-899	57	10	confirmed	confirm	VERB
biomedich-899	57	11	with	with	ADP
biomedich-899	57	12	atr	atr	NOUN
biomedich-899	57	13	-	-	PUNCT
biomedich-899	57	14	ftir	ftir	PROPN
biomedich-899	57	15	,	,	PUNCT
biomedich-899	57	16	1h	1h	NUM
biomedich-899	57	17	-	-	PUNCT
biomedich-899	57	18	nmr	nmr	NOUN
biomedich-899	57	19	and	and	CCONJ
biomedich-899	57	20	13cnmr	13cnmr	NUM
biomedich-899	57	21	.	.	PUNCT
biomedich-899	58	1	atr	atr	PROPN
biomedich-899	58	2	-	-	PUNCT
biomedich-899	58	3	ftir	ftir	ADJ
biomedich-899	58	4	analysis	analysis	NOUN
biomedich-899	58	5	was	be	AUX
biomedich-899	58	6	performed	perform	VERB
biomedich-899	58	7	on	on	ADP
biomedich-899	58	8	a	a	DET
biomedich-899	58	9	nicolet	nicolet	PROPN
biomedich-899	58	10	6700	6700	NUM
biomedich-899	58	11	ftir	ftir	PROPN
biomedich-899	58	12	spectrometer	spectrometer	NOUN
biomedich-899	58	13	.	.	PUNCT
biomedich-899	59	1	1h	1h	NUM
biomedich-899	59	2	-	-	PUNCT
biomedich-899	59	3	nmr	nmr	NOUN
biomedich-899	59	4	and	and	CCONJ
biomedich-899	59	5	13c	13c	NOUN
biomedich-899	59	6	-	-	NOUN
biomedich-899	59	7	nmr	nmr	NOUN
biomedich-899	59	8	were	be	AUX
biomedich-899	59	9	performed	perform	VERB
biomedich-899	59	10	on	on	ADP
biomedich-899	59	11	a	a	DET
biomedich-899	59	12	bruker	bruker	NOUN
biomedich-899	59	13	400	400	NUM
biomedich-899	59	14	mhz	mhz	NOUN
biomedich-899	59	15	spectrometer	spectrometer	NOUN
biomedich-899	59	16	.	.	PUNCT
biomedich-899	60	1	chitosan	chitosan	PROPN
biomedich-899	60	2	,	,	PUNCT
biomedich-899	60	3	o	o	NOUN
biomedich-899	60	4	-	-	ADJ
biomedich-899	60	5	sulfate	sulfate	NOUN
biomedich-899	60	6	-	-	PUNCT
biomedich-899	60	7	chitosan	chitosan	NOUN
biomedich-899	60	8	,	,	PUNCT
biomedich-899	60	9	n	n	CCONJ
biomedich-899	60	10	-	-	PUNCT
biomedich-899	60	11	anisimine	anisimine	NOUN
biomedich-899	60	12	-	-	PUNCT
biomedich-899	60	13	o	o	NOUN
biomedich-899	60	14	-	-	NOUN
biomedich-899	60	15	sulfate	sulfate	NOUN
biomedich-899	60	16	-	-	PUNCT
biomedich-899	60	17	chitosan	chitosan	NOUN
biomedich-899	60	18	were	be	AUX
biomedich-899	60	19	dissolved	dissolve	VERB
biomedich-899	60	20	in	in	ADP
biomedich-899	60	21	the	the	DET
biomedich-899	60	22	mixed	mixed	ADJ
biomedich-899	60	23	solvent	solvent	NOUN
biomedich-899	60	24	of	of	ADP
biomedich-899	60	25	d2o	d2o	PROPN
biomedich-899	60	26	and	and	CCONJ
biomedich-899	60	27	cf3cooh	cf3cooh	PROPN
biomedich-899	60	28	.	.	PUNCT
biomedich-899	61	1	the	the	DET
biomedich-899	61	2	degree	degree	NOUN
biomedich-899	61	3	of	of	ADP
biomedich-899	61	4	substitution	substitution	NOUN
biomedich-899	61	5	(	(	PUNCT
biomedich-899	61	6	ds	ds	NOUN
biomedich-899	61	7	)	)	PUNCT
biomedich-899	61	8	for	for	ADP
biomedich-899	61	9	the	the	DET
biomedich-899	61	10	derivatives	derivative	NOUN
biomedich-899	61	11	was	be	AUX
biomedich-899	61	12	calculated	calculate	VERB
biomedich-899	61	13	using	use	VERB
biomedich-899	61	14	the	the	DET
biomedich-899	61	15	integration	integration	NOUN
biomedich-899	61	16	of	of	ADP
biomedich-899	61	17	nmr	nmr	NOUN
biomedich-899	61	18	peaks	peak	NOUN
biomedich-899	61	19	(	(	PUNCT
biomedich-899	61	20	jaidee	jaidee	PROPN
biomedich-899	61	21	et	et	PROPN
biomedich-899	61	22	al	al	PROPN
biomedich-899	61	23	.	.	PROPN
biomedich-899	61	24	,	,	PUNCT
biomedich-899	61	25	2012	2012	NUM
biomedich-899	61	26	):	):	PUNCT
biomedich-899	61	27	%	%	INTJ
biomedich-899	61	28	ds	ds	NOUN
biomedich-899	61	29	of	of	ADP
biomedich-899	61	30	anisaldehyde	anisaldehyde	NOUN
biomedich-899	62	1	=	=	SYM
biomedich-899	62	2	(	(	PUNCT
biomedich-899	62	3	∫	∫	PROPN
biomedich-899	62	4	𝐻7.0+𝐻7.78+𝐻9.63	𝐻7.0+𝐻7.78+𝐻9.63	PROPN
biomedich-899	62	5	)	)	PUNCT
biomedich-899	62	6	5	5	NUM
biomedich-899	62	7	∫	∫	NOUN
biomedich-899	62	8	𝐻3,05	𝐻3,05	VERB
biomedich-899	62	9	determination	determination	NOUN
biomedich-899	62	10	of	of	ADP
biomedich-899	62	11	critical	critical	ADJ
biomedich-899	62	12	micelle	micelle	NOUN
biomedich-899	62	13	concentration	concentration	NOUN
biomedich-899	62	14	the	the	DET
biomedich-899	62	15	cmc	cmc	NOUN
biomedich-899	62	16	of	of	ADP
biomedich-899	62	17	chitosan	chitosan	ADJ
biomedich-899	62	18	derivative	derivative	NOUN
biomedich-899	62	19	was	be	AUX
biomedich-899	62	20	determined	determine	VERB
biomedich-899	62	21	using	use	VERB
biomedich-899	62	22	pyrene	pyrene	NOUN
biomedich-899	62	23	as	as	ADP
biomedich-899	62	24	a	a	DET
biomedich-899	62	25	hydrophobic	hydrophobic	NOUN
biomedich-899	62	26	probe	probe	NOUN
biomedich-899	62	27	(	(	PUNCT
biomedich-899	62	28	aguiar	aguiar	NOUN
biomedich-899	62	29	et	et	PROPN
biomedich-899	62	30	al	al	PROPN
biomedich-899	62	31	.	.	PROPN
biomedich-899	62	32	,	,	PUNCT
biomedich-899	62	33	2003	2003	NUM
biomedich-899	62	34	)	)	PUNCT
biomedich-899	62	35	.	.	PUNCT
biomedich-899	63	1	a	a	DET
biomedich-899	63	2	solution	solution	NOUN
biomedich-899	63	3	of	of	ADP
biomedich-899	63	4	pyrene	pyrene	NOUN
biomedich-899	63	5	in	in	ADP
biomedich-899	63	6	acetone	acetone	NOUN
biomedich-899	63	7	(	(	PUNCT
biomedich-899	63	8	6	6	NUM
biomedich-899	63	9	×	×	NOUN
biomedich-899	63	10	10⁻⁵	10⁻⁵	NUM
biomedich-899	63	11	m	m	NOUN
biomedich-899	63	12	)	)	PUNCT
biomedich-899	63	13	was	be	AUX
biomedich-899	63	14	prepared	prepare	VERB
biomedich-899	63	15	,	,	PUNCT
biomedich-899	63	16	and	and	CCONJ
biomedich-899	63	17	10	10	NUM
biomedich-899	63	18	μl	μl	INTJ
biomedich-899	63	19	was	be	AUX
biomedich-899	63	20	added	add	VERB
biomedich-899	63	21	to	to	ADP
biomedich-899	63	22	eppendorf	eppendorf	PROPN
biomedich-899	63	23	tubes	tube	NOUN
biomedich-899	63	24	.	.	PUNCT
biomedich-899	64	1	the	the	DET
biomedich-899	64	2	acetone	acetone	NOUN
biomedich-899	64	3	was	be	AUX
biomedich-899	64	4	evaporated	evaporate	VERB
biomedich-899	64	5	before	before	ADP
biomedich-899	64	6	adding	add	VERB
biomedich-899	64	7	1	1	NUM
biomedich-899	64	8	ml	ml	NOUN
biomedich-899	64	9	of	of	ADP
biomedich-899	64	10	chitosan	chitosan	ADJ
biomedich-899	64	11	derivative	derivative	ADJ
biomedich-899	64	12	solutions	solution	NOUN
biomedich-899	64	13	(	(	PUNCT
biomedich-899	64	14	concentrations	concentration	NOUN
biomedich-899	64	15	ranging	range	VERB
biomedich-899	64	16	from	from	ADP
biomedich-899	64	17	0.01	0.01	NUM
biomedich-899	64	18	to	to	ADP
biomedich-899	64	19	0.6	0.6	NUM
biomedich-899	64	20	mg	mg	PROPN
biomedich-899	64	21	/	/	SYM
biomedich-899	64	22	ml	ml	NOUN
biomedich-899	64	23	)	)	PUNCT
biomedich-899	64	24	.	.	PUNCT
biomedich-899	65	1	the	the	DET
biomedich-899	65	2	solutions	solution	NOUN
biomedich-899	65	3	were	be	AUX
biomedich-899	65	4	sonicated	sonicate	VERB
biomedich-899	65	5	at	at	ADP
biomedich-899	65	6	room	room	NOUN
biomedich-899	65	7	temperature	temperature	NOUN
biomedich-899	65	8	for	for	ADP
biomedich-899	65	9	30	30	NUM
biomedich-899	65	10	minutes	minute	NOUN
biomedich-899	65	11	and	and	CCONJ
biomedich-899	65	12	equilibrated	equilibrate	VERB
biomedich-899	65	13	at	at	ADP
biomedich-899	65	14	65	65	NUM
biomedich-899	65	15	℃	℃	PROPN
biomedich-899	65	16	for	for	ADP
biomedich-899	65	17	3	3	NUM
biomedich-899	65	18	hours	hour	NOUN
biomedich-899	65	19	.	.	PUNCT
biomedich-899	66	1	fluorescence	fluorescence	PROPN
biomedich-899	66	2	emission	emission	NOUN
biomedich-899	66	3	spectra	spectra	NOUN
biomedich-899	66	4	(	(	PUNCT
biomedich-899	66	5	350–450	350–450	NUM
biomedich-899	66	6	nm	nm	NOUN
biomedich-899	66	7	)	)	PUNCT
biomedich-899	66	8	were	be	AUX
biomedich-899	66	9	recorded	record	VERB
biomedich-899	66	10	using	use	VERB
biomedich-899	66	11	an	an	DET
biomedich-899	66	12	excitation	excitation	NOUN
biomedich-899	66	13	wavelength	wavelength	NOUN
biomedich-899	66	14	of	of	ADP
biomedich-899	66	15	336	336	NUM
biomedich-899	66	16	nm	nm	NOUN
biomedich-899	66	17	on	on	ADP
biomedich-899	66	18	a	a	DET
biomedich-899	66	19	fluorescence	fluorescence	NOUN
biomedich-899	66	20	spectrophotometer	spectrophotometer	NOUN
biomedich-899	66	21	.	.	PUNCT
biomedich-899	67	1	both	both	DET
biomedich-899	67	2	excitation	excitation	NOUN
biomedich-899	67	3	and	and	CCONJ
biomedich-899	67	4	emission	emission	NOUN
biomedich-899	67	5	bandwidths	bandwidth	NOUN
biomedich-899	67	6	were	be	AUX
biomedich-899	67	7	set	set	VERB
biomedich-899	67	8	at	at	ADP
biomedich-899	67	9	5	5	NUM
biomedich-899	67	10	nm	nm	NOUN
biomedich-899	67	11	.	.	PUNCT
biomedich-899	68	1	the	the	DET
biomedich-899	68	2	cmc	cmc	NOUN
biomedich-899	68	3	values	value	NOUN
biomedich-899	68	4	were	be	AUX
biomedich-899	68	5	calculated	calculate	VERB
biomedich-899	68	6	based	base	VERB
biomedich-899	68	7	on	on	ADP
biomedich-899	68	8	the	the	DET
biomedich-899	68	9	pyrene	pyrene	PROPN
biomedich-899	68	10	emission	emission	NOUN
biomedich-899	68	11	spectra	spectra	PROPN
biomedich-899	68	12	.	.	PUNCT
biomedich-899	69	1	herayati	herayati	PROPN
biomedich-899	69	2	et	et	PROPN
biomedich-899	69	3	al	al	PROPN
biomedich-899	69	4	.	.	PROPN
biomedich-899	69	5	–	–	PUNCT
biomedich-899	69	6	synthesis	synthesis	NOUN
biomedich-899	69	7	,	,	PUNCT
biomedich-899	69	8	characterization	characterization	NOUN
biomedich-899	69	9	,	,	PUNCT
biomedich-899	69	10	and	and	CCONJ
biomedich-899	69	11	micellar	micellar	ADJ
biomedich-899	69	12	behavior	behavior	NOUN
biomedich-899	69	13	of	of	ADP
biomedich-899	69	14	…	…	PUNCT
biomedich-899	69	15	907	907	NUM
biomedich-899	69	16	results	result	NOUN
biomedich-899	69	17	and	and	CCONJ
biomedich-899	69	18	discussion	discussion	VERB
biomedich-899	69	19	the	the	DET
biomedich-899	69	20	result	result	NOUN
biomedich-899	69	21	of	of	ADP
biomedich-899	69	22	ir	ir	PROPN
biomedich-899	69	23	and	and	CCONJ
biomedich-899	69	24	1h	1h	NUM
biomedich-899	69	25	-	-	PUNCT
biomedich-899	69	26	nmr	nmr	NOUN
biomedich-899	69	27	analysis	analysis	NOUN
biomedich-899	69	28	4000	4000	NUM
biomedich-899	69	29	3500	3500	NUM
biomedich-899	69	30	3000	3000	NUM
biomedich-899	69	31	2500	2500	NUM
biomedich-899	69	32	2000	2000	NUM
biomedich-899	69	33	1500	1500	NUM
biomedich-899	69	34	1000	1000	NUM
biomedich-899	70	1	c	c	X
biomedich-899	70	2	=	=	NOUN
biomedich-899	70	3	c	c	NOUN
biomedich-899	70	4	aromatik	aromatik	NOUN
biomedich-899	70	5	(	(	PUNCT
biomedich-899	70	6	c	c	NOUN
biomedich-899	70	7	-	-	PUNCT
biomedich-899	70	8	oso	oso	NOUN
biomedich-899	70	9	3	3	NUM
biomedich-899	70	10	)	)	PUNCT
biomedich-899	70	11	o	o	NOUN
biomedich-899	70	12	-	-	PUNCT
biomedich-899	70	13	s	s	X
biomedich-899	70	14	(	(	PUNCT
biomedich-899	70	15	c	c	NOUN
biomedich-899	70	16	-	-	PUNCT
biomedich-899	70	17	oso	oso	NOUN
biomedich-899	70	18	3	3	NUM
biomedich-899	70	19	)	)	PUNCT
biomedich-899	70	20	c	c	NOUN
biomedich-899	70	21	-	-	PUNCT
biomedich-899	70	22	o	o	NOUN
biomedich-899	71	1	so	so	ADV
biomedich-899	71	2	2	2	NUM
biomedich-899	71	3	t	t	NOUN
biomedich-899	71	4	ra	ra	NOUN
biomedich-899	72	1	n	n	ADV
biomedich-899	72	2	sm	sm	VERB
biomedich-899	72	3	it	it	PRON
biomedich-899	72	4	an	an	DET
biomedich-899	72	5	ce	ce	PROPN
biomedich-899	72	6	(	(	PUNCT
biomedich-899	72	7	a.	a.	NOUN
biomedich-899	72	8	u	u	PROPN
biomedich-899	72	9	.	.	PUNCT
biomedich-899	72	10	)	)	PUNCT
biomedich-899	73	1	wavenumber	wavenumber	NOUN
biomedich-899	73	2	(	(	PUNCT
biomedich-899	73	3	cm	cm	NOUN
biomedich-899	73	4	-1	-1	PUNCT
biomedich-899	73	5	)	)	PUNCT
biomedich-899	74	1	c	c	X
biomedich-899	74	2	=	=	SYM
biomedich-899	74	3	n	n	DET
biomedich-899	74	4	a	a	PRON
biomedich-899	74	5	b	b	NOUN
biomedich-899	74	6	c	c	X
biomedich-899	74	7	figure	figure	NOUN
biomedich-899	74	8	1	1	NUM
biomedich-899	74	9	.	.	X
biomedich-899	74	10	ftir	ftir	PROPN
biomedich-899	74	11	and	and	CCONJ
biomedich-899	74	12	1h	1h	NUM
biomedich-899	74	13	-	-	PUNCT
biomedich-899	74	14	nmr	nmr	NOUN
biomedich-899	74	15	spectra	spectra	NOUN
biomedich-899	74	16	of	of	ADP
biomedich-899	74	17	chitosan	chitosan	NOUN
biomedich-899	74	18	(	(	PUNCT
biomedich-899	74	19	a	a	NOUN
biomedich-899	74	20	)	)	PUNCT
biomedich-899	74	21	,	,	PUNCT
biomedich-899	74	22	o	o	NOUN
biomedich-899	74	23	-	-	NOUN
biomedich-899	74	24	sulfate	sulfate	NOUN
biomedich-899	74	25	-	-	PUNCT
biomedich-899	74	26	chitosan	chitosan	NOUN
biomedich-899	74	27	(	(	PUNCT
biomedich-899	74	28	b	b	NOUN
biomedich-899	74	29	)	)	PUNCT
biomedich-899	74	30	and	and	CCONJ
biomedich-899	74	31	naos	naos	PROPN
biomedich-899	74	32	-	-	PUNCT
biomedich-899	74	33	chitosan	chitosan	PROPN
biomedich-899	74	34	(	(	PUNCT
biomedich-899	74	35	ds	ds	PRON
biomedich-899	74	36	96	96	NUM
biomedich-899	74	37	%	%	NOUN
biomedich-899	74	38	anisimine	anisimine	NOUN
biomedich-899	74	39	(	(	PUNCT
biomedich-899	74	40	c	c	NOUN
biomedich-899	74	41	)	)	PUNCT
biomedich-899	74	42	and	and	CCONJ
biomedich-899	74	43	ds	ds	PRON
biomedich-899	74	44	49	49	NUM
biomedich-899	74	45	%	%	NOUN
biomedich-899	74	46	anisimine	anisimine	NOUN
biomedich-899	74	47	(	(	PUNCT
biomedich-899	74	48	d	d	NOUN
biomedich-899	74	49	)	)	PUNCT
biomedich-899	74	50	)	)	PUNCT
biomedich-899	74	51	table	table	NOUN
biomedich-899	74	52	1	1	NUM
biomedich-899	74	53	.	.	NOUN
biomedich-899	74	54	degree	degree	NOUN
biomedich-899	74	55	of	of	ADP
biomedich-899	74	56	substitution	substitution	NOUN
biomedich-899	74	57	of	of	ADP
biomedich-899	74	58	amphiphilic	amphiphilic	ADJ
biomedich-899	74	59	chitosan	chitosan	NOUN
biomedich-899	74	60	derivatives	derivative	NOUN
biomedich-899	74	61	.	.	PUNCT
biomedich-899	75	1	mol	mol	ADP
biomedich-899	75	2	ratio	ratio	NOUN
biomedich-899	75	3	of	of	ADP
biomedich-899	75	4	cho	cho	NOUN
biomedich-899	75	5	:	:	PUNCT
biomedich-899	75	6	nh2	nh2	NOUN
biomedich-899	75	7	integration	integration	NOUN
biomedich-899	75	8	value	value	NOUN
biomedich-899	75	9	ds(%	ds(%	NOUN
biomedich-899	75	10	)	)	PUNCT
biomedich-899	76	1	h3.05	h3.05	PROPN
biomedich-899	76	2	h7.08	h7.08	PROPN
biomedich-899	76	3	h7.81	h7.81	PROPN
biomedich-899	76	4	h9.65	h9.65	ADP
biomedich-899	76	5	3	3	NUM
biomedich-899	76	6	:	:	SYM
biomedich-899	76	7	1	1	NUM
biomedich-899	76	8	2.49	2.49	NUM
biomedich-899	76	9	4.84	4.84	NUM
biomedich-899	76	10	4.95	4.95	NUM
biomedich-899	76	11	2.16	2.16	NUM
biomedich-899	76	12	96	96	NUM
biomedich-899	76	13	1	1	NUM
biomedich-899	76	14	:	:	SYM
biomedich-899	76	15	1	1	NUM
biomedich-899	76	16	2.22	2.22	NUM
biomedich-899	76	17	2.05	2.05	NUM
biomedich-899	76	18	2.28	2.28	NUM
biomedich-899	76	19	1.11	1.11	NUM
biomedich-899	76	20	49	49	NUM
biomedich-899	76	21	the	the	DET
biomedich-899	76	22	result	result	NOUN
biomedich-899	76	23	of	of	ADP
biomedich-899	76	24	micelar	micelar	ADJ
biomedich-899	76	25	behaviour	behaviour	NOUN
biomedich-899	76	26	-1,8	-1,8	PUNCT
biomedich-899	76	27	-1,6	-1,6	INTJ
biomedich-899	77	1	-1,4	-1,4	PROPN
biomedich-899	77	2	-1,2	-1,2	PROPN
biomedich-899	78	1	-1,0	-1,0	PROPN
biomedich-899	78	2	-0,8	-0,8	INTJ
biomedich-899	78	3	-0,6	-0,6	PROPN
biomedich-899	78	4	-0,4	-0,4	PUNCT
biomedich-899	78	5	-0,2	-0,2	PROPN
biomedich-899	78	6	0,0	0,0	NUM
biomedich-899	79	1	0,8	0,8	NUM
biomedich-899	79	2	1,0	1,0	NUM
biomedich-899	79	3	1,2	1,2	NUM
biomedich-899	79	4	1,4	1,4	NUM
biomedich-899	79	5	1,6	1,6	NUM
biomedich-899	79	6	i	i	NOUN
biomedich-899	79	7	3	3	NUM
biomedich-899	79	8	8	8	NUM
biomedich-899	79	9	4	4	NUM
biomedich-899	79	10	/i	/i	SYM
biomedich-899	79	11	3	3	NUM
biomedich-899	79	12	7	7	NUM
biomedich-899	79	13	2	2	NUM
biomedich-899	79	14	log	log	NOUN
biomedich-899	79	15	c	c	NOUN
biomedich-899	79	16	figure	figure	NOUN
biomedich-899	79	17	2	2	NUM
biomedich-899	79	18	.	.	PUNCT
biomedich-899	80	1	intensity	intensity	NOUN
biomedich-899	80	2	ratio	ratio	NOUN
biomedich-899	80	3	plots	plot	NOUN
biomedich-899	80	4	of	of	ADP
biomedich-899	80	5	i384	i384	PROPN
biomedich-899	80	6	/	/	SYM
biomedich-899	80	7	i372	i372	PROPN
biomedich-899	80	8	versus	versus	ADP
biomedich-899	80	9	log	log	NOUN
biomedich-899	80	10	c	c	PROPN
biomedich-899	80	11	for	for	ADP
biomedich-899	80	12	naoschitosan	naoschitosan	ADJ
biomedich-899	80	13	(	(	PUNCT
biomedich-899	80	14	96	96	NUM
biomedich-899	80	15	%	%	NOUN
biomedich-899	80	16	degree	degree	NOUN
biomedich-899	80	17	of	of	ADP
biomedich-899	80	18	substitution	substitution	NOUN
biomedich-899	80	19	)	)	PUNCT
biomedich-899	80	20	in	in	ADP
biomedich-899	80	21	water	water	NOUN
biomedich-899	80	22	discussion	discussion	NOUN
biomedich-899	80	23	the	the	DET
biomedich-899	80	24	synthesis	synthesis	NOUN
biomedich-899	80	25	of	of	ADP
biomedich-899	80	26	the	the	DET
biomedich-899	80	27	novel	novel	ADJ
biomedich-899	80	28	amphiphilic	amphiphilic	ADJ
biomedich-899	80	29	chitosan	chitosan	NOUN
biomedich-899	80	30	derivatives	derivative	NOUN
biomedich-899	80	31	bearing	bear	VERB
biomedich-899	80	32	sulfate	sulfate	NOUN
biomedich-899	80	33	and	and	CCONJ
biomedich-899	80	34	anisimine	anisimine	VERB
biomedich-899	80	35	functional	functional	ADJ
biomedich-899	80	36	groups	group	NOUN
biomedich-899	80	37	were	be	AUX
biomedich-899	80	38	achieved	achieve	VERB
biomedich-899	80	39	through	through	ADP
biomedich-899	80	40	a	a	DET
biomedich-899	80	41	stepwise	stepwise	ADJ
biomedich-899	80	42	reaction	reaction	NOUN
biomedich-899	80	43	pathway	pathway	NOUN
biomedich-899	80	44	,	,	PUNCT
biomedich-899	80	45	as	as	SCONJ
biomedich-899	80	46	depicted	depict	VERB
biomedich-899	80	47	in	in	ADP
biomedich-899	80	48	the	the	DET
biomedich-899	80	49	reaction	reaction	NOUN
biomedich-899	80	50	scheme	scheme	NOUN
biomedich-899	80	51	(	(	PUNCT
biomedich-899	80	52	figure	figure	NOUN
biomedich-899	80	53	3	3	NUM
biomedich-899	80	54	)	)	PUNCT
biomedich-899	80	55	.	.	PUNCT
biomedich-899	81	1	the	the	DET
biomedich-899	81	2	first	first	ADJ
biomedich-899	81	3	step	step	NOUN
biomedich-899	81	4	involved	involve	VERB
biomedich-899	81	5	the	the	DET
biomedich-899	81	6	sulfation	sulfation	NOUN
biomedich-899	81	7	of	of	ADP
biomedich-899	81	8	chitosan	chitosan	NOUN
biomedich-899	81	9	using	use	VERB
biomedich-899	81	10	chlorosulfonic	chlorosulfonic	ADJ
biomedich-899	81	11	acid	acid	NOUN
biomedich-899	81	12	,	,	PUNCT
biomedich-899	81	13	which	which	PRON
biomedich-899	81	14	selectively	selectively	ADV
biomedich-899	81	15	reacted	react	VERB
biomedich-899	81	16	with	with	ADP
biomedich-899	81	17	the	the	DET
biomedich-899	81	18	hydroxyl	hydroxyl	NOUN
biomedich-899	81	19	groups	group	NOUN
biomedich-899	81	20	of	of	ADP
biomedich-899	81	21	the	the	DET
biomedich-899	81	22	glucosamine	glucosamine	NOUN
biomedich-899	81	23	units	unit	NOUN
biomedich-899	81	24	in	in	ADP
biomedich-899	81	25	the	the	DET
biomedich-899	81	26	chitosan	chitosan	ADJ
biomedich-899	81	27	backbone	backbone	NOUN
biomedich-899	81	28	.	.	PUNCT
biomedich-899	82	1	the	the	DET
biomedich-899	82	2	introduction	introduction	NOUN
biomedich-899	82	3	of	of	ADP
biomedich-899	82	4	sulfate	sulfate	NOUN
biomedich-899	82	5	groups	group	NOUN
biomedich-899	82	6	(	(	PUNCT
biomedich-899	82	7	–	–	PUNCT
biomedich-899	82	8	oso₃⁻	oso₃⁻	NOUN
biomedich-899	82	9	)	)	PUNCT
biomedich-899	82	10	into	into	ADP
biomedich-899	82	11	the	the	DET
biomedich-899	82	12	polymer	polymer	NOUN
biomedich-899	82	13	structure	structure	NOUN
biomedich-899	82	14	significantly	significantly	ADV
biomedich-899	82	15	enhanced	enhance	VERB
biomedich-899	82	16	its	its	PRON
biomedich-899	82	17	hydrophilic	hydrophilic	ADJ
biomedich-899	82	18	properties	property	NOUN
biomedich-899	82	19	,	,	PUNCT
biomedich-899	82	20	making	make	VERB
biomedich-899	82	21	the	the	DET
biomedich-899	82	22	modified	modify	VERB
biomedich-899	82	23	chitosan	chitosan	NOUN
biomedich-899	82	24	more	more	ADV
biomedich-899	82	25	soluble	soluble	ADJ
biomedich-899	82	26	and	and	CCONJ
biomedich-899	82	27	reactive	reactive	ADJ
biomedich-899	82	28	in	in	ADP
biomedich-899	82	29	aqueous	aqueous	ADJ
biomedich-899	82	30	environments	environment	NOUN
biomedich-899	82	31	.	.	PUNCT
biomedich-899	83	1	the	the	DET
biomedich-899	83	2	presence	presence	NOUN
biomedich-899	83	3	of	of	ADP
biomedich-899	83	4	20	20	NUM
biomedich-899	83	5	%	%	NOUN
biomedich-899	83	6	sodium	sodium	NOUN
biomedich-899	83	7	hydroxide	hydroxide	NOUN
biomedich-899	83	8	(	(	PUNCT
biomedich-899	83	9	naoh	naoh	NOUN
biomedich-899	83	10	)	)	PUNCT
biomedich-899	83	11	played	play	VERB
biomedich-899	83	12	a	a	DET
biomedich-899	83	13	crucial	crucial	ADJ
biomedich-899	83	14	role	role	NOUN
biomedich-899	83	15	in	in	ADP
biomedich-899	83	16	this	this	DET
biomedich-899	83	17	step	step	NOUN
biomedich-899	83	18	,	,	PUNCT
biomedich-899	83	19	acting	act	VERB
biomedich-899	83	20	to	to	PART
biomedich-899	83	21	neutralize	neutralize	VERB
biomedich-899	83	22	the	the	DET
biomedich-899	83	23	reaction	reaction	NOUN
biomedich-899	83	24	mixture	mixture	NOUN
biomedich-899	83	25	and	and	CCONJ
biomedich-899	83	26	terminate	terminate	VERB
biomedich-899	83	27	the	the	DET
biomedich-899	83	28	sulfation	sulfation	NOUN
biomedich-899	83	29	process	process	NOUN
biomedich-899	83	30	.	.	PUNCT
biomedich-899	84	1	by	by	ADP
biomedich-899	84	2	reacting	react	VERB
biomedich-899	84	3	with	with	ADP
biomedich-899	84	4	excess	excess	ADJ
biomedich-899	84	5	chlorosulfonic	chlorosulfonic	ADJ
biomedich-899	84	6	acid	acid	NOUN
biomedich-899	84	7	,	,	PUNCT
biomedich-899	84	8	naoh	naoh	NOUN
biomedich-899	84	9	prevented	prevent	VERB
biomedich-899	84	10	over	over	ADP
biomedich-899	84	11	-	-	PUNCT
biomedich-899	84	12	sulfation	sulfation	NOUN
biomedich-899	84	13	and	and	CCONJ
biomedich-899	84	14	degradation	degradation	NOUN
biomedich-899	84	15	of	of	ADP
biomedich-899	84	16	the	the	DET
biomedich-899	84	17	chitosan	chitosan	ADJ
biomedich-899	84	18	backbone	backbone	NOUN
biomedich-899	84	19	(	(	PUNCT
biomedich-899	84	20	diab	diab	PROPN
biomedich-899	84	21	et	et	PROPN
biomedich-899	84	22	al	al	PROPN
biomedich-899	84	23	.	.	PROPN
biomedich-899	84	24	,	,	PUNCT
biomedich-899	84	25	2012	2012	NUM
biomedich-899	84	26	)	)	PUNCT
biomedich-899	84	27	,	,	PUNCT
biomedich-899	84	28	ensuring	ensure	VERB
biomedich-899	84	29	the	the	DET
biomedich-899	84	30	preservation	preservation	NOUN
biomedich-899	84	31	of	of	ADP
biomedich-899	84	32	the	the	DET
biomedich-899	84	33	polymer	polymer	NOUN
biomedich-899	84	34	's	's	PART
biomedich-899	84	35	structural	structural	ADJ
biomedich-899	84	36	integrity	integrity	NOUN
biomedich-899	84	37	.	.	PUNCT
biomedich-899	85	1	this	this	DET
biomedich-899	85	2	controlled	control	VERB
biomedich-899	85	3	reaction	reaction	NOUN
biomedich-899	85	4	allowed	allow	VERB
biomedich-899	85	5	the	the	DET
biomedich-899	85	6	incorporation	incorporation	NOUN
biomedich-899	85	7	of	of	ADP
biomedich-899	85	8	sulfate	sulfate	NOUN
biomedich-899	85	9	groups	group	NOUN
biomedich-899	85	10	while	while	SCONJ
biomedich-899	85	11	maintaining	maintain	VERB
biomedich-899	85	12	the	the	DET
biomedich-899	85	13	desirable	desirable	ADJ
biomedich-899	85	14	physical	physical	ADJ
biomedich-899	85	15	and	and	CCONJ
biomedich-899	85	16	chemical	chemical	NOUN
biomedich-899	85	17	characteristics	characteristic	NOUN
biomedich-899	85	18	of	of	ADP
biomedich-899	85	19	chitosan	chitosan	NOUN
biomedich-899	85	20	.	.	PUNCT
biomedich-899	86	1	this	this	DET
biomedich-899	86	2	sulfated	sulfate	VERB
biomedich-899	86	3	intermediate	intermediate	NOUN
biomedich-899	86	4	served	serve	VERB
biomedich-899	86	5	as	as	ADP
biomedich-899	86	6	a	a	DET
biomedich-899	86	7	critical	critical	ADJ
biomedich-899	86	8	precursor	precursor	NOUN
biomedich-899	86	9	for	for	ADP
biomedich-899	86	10	the	the	DET
biomedich-899	86	11	subsequent	subsequent	ADJ
biomedich-899	86	12	functionalization	functionalization	NOUN
biomedich-899	86	13	step	step	NOUN
biomedich-899	86	14	,	,	PUNCT
biomedich-899	86	15	providing	provide	VERB
biomedich-899	86	16	the	the	DET
biomedich-899	86	17	necessary	necessary	ADJ
biomedich-899	86	18	hydrophilic	hydrophilic	ADJ
biomedich-899	86	19	balance	balance	NOUN
biomedich-899	86	20	to	to	PART
biomedich-899	86	21	support	support	VERB
biomedich-899	86	22	amphiphilic	amphiphilic	ADJ
biomedich-899	86	23	behavior	behavior	NOUN
biomedich-899	86	24	after	after	ADP
biomedich-899	86	25	the	the	DET
biomedich-899	86	26	introduction	introduction	NOUN
biomedich-899	86	27	of	of	ADP
biomedich-899	86	28	hydrophobic	hydrophobic	NOUN
biomedich-899	86	29	groups	group	NOUN
biomedich-899	86	30	.	.	PUNCT
biomedich-899	87	1	in	in	ADP
biomedich-899	87	2	the	the	DET
biomedich-899	87	3	subsequent	subsequent	ADJ
biomedich-899	87	4	step	step	NOUN
biomedich-899	87	5	,	,	PUNCT
biomedich-899	87	6	the	the	DET
biomedich-899	87	7	sulfated	sulfated	ADJ
biomedich-899	87	8	chitosan	chitosan	NOUN
biomedich-899	87	9	was	be	AUX
biomedich-899	87	10	subjected	subject	VERB
biomedich-899	87	11	to	to	ADP
biomedich-899	87	12	schiff	schiff	VERB
biomedich-899	87	13	base	base	NOUN
biomedich-899	87	14	formation	formation	NOUN
biomedich-899	87	15	by	by	ADP
biomedich-899	87	16	reacting	react	VERB
biomedich-899	87	17	with	with	ADP
biomedich-899	87	18	panisaldehyde	panisaldehyde	NOUN
biomedich-899	87	19	in	in	ADP
biomedich-899	87	20	a	a	DET
biomedich-899	87	21	dimethylformamide	dimethylformamide	NOUN
biomedich-899	87	22	(	(	PUNCT
biomedich-899	87	23	dmf	dmf	PROPN
biomedich-899	87	24	)	)	PUNCT
biomedich-899	87	25	.	.	PUNCT
biomedich-899	88	1	this	this	DET
biomedich-899	88	2	reaction	reaction	NOUN
biomedich-899	88	3	facilitated	facilitate	VERB
biomedich-899	88	4	the	the	DET
biomedich-899	88	5	covalent	covalent	ADJ
biomedich-899	88	6	attachment	attachment	NOUN
biomedich-899	88	7	of	of	ADP
biomedich-899	88	8	the	the	DET
biomedich-899	88	9	aromatic	aromatic	ADJ
biomedich-899	88	10	imine	imine	NOUN
biomedich-899	88	11	group	group	NOUN
biomedich-899	88	12	via	via	ADP
biomedich-899	88	13	condensation	condensation	NOUN
biomedich-899	88	14	between	between	ADP
biomedich-899	88	15	the	the	DET
biomedich-899	88	16	primary	primary	ADJ
biomedich-899	88	17	amine	amine	ADJ
biomedich-899	88	18	groups	group	NOUN
biomedich-899	88	19	of	of	ADP
biomedich-899	88	20	chitosan	chitosan	NOUN
biomedich-899	88	21	and	and	CCONJ
biomedich-899	88	22	the	the	DET
biomedich-899	88	23	aldehyde	aldehyde	NOUN
biomedich-899	88	24	functionality	functionality	NOUN
biomedich-899	88	25	of	of	ADP
biomedich-899	88	26	p	p	PROPN
biomedich-899	88	27	-	-	PUNCT
biomedich-899	88	28	anisaldehyde	anisaldehyde	NOUN
biomedich-899	88	29	,	,	PUNCT
biomedich-899	88	30	yielding	yield	VERB
biomedich-899	88	31	the	the	DET
biomedich-899	88	32	desired	desire	VERB
biomedich-899	88	33	imine	imine	NOUN
biomedich-899	88	34	bond	bond	NOUN
biomedich-899	88	35	(	(	PUNCT
biomedich-899	88	36	c	c	NOUN
biomedich-899	88	37	=	=	SYM
biomedich-899	88	38	n	n	NUM
biomedich-899	88	39	)	)	PUNCT
biomedich-899	88	40	.	.	PUNCT
biomedich-899	89	1	the	the	DET
biomedich-899	89	2	aromatic	aromatic	ADJ
biomedich-899	89	3	group	group	NOUN
biomedich-899	89	4	from	from	ADP
biomedich-899	89	5	panisaldehyde	panisaldehyde	PROPN
biomedich-899	89	6	introduced	introduce	VERB
biomedich-899	89	7	hydrophobicity	hydrophobicity	NOUN
biomedich-899	89	8	,	,	PUNCT
biomedich-899	89	9	resulting	result	VERB
biomedich-899	89	10	in	in	ADP
biomedich-899	89	11	an	an	DET
biomedich-899	89	12	amphiphilic	amphiphilic	ADJ
biomedich-899	89	13	structure	structure	NOUN
biomedich-899	89	14	.	.	PUNCT
biomedich-899	90	1	908	908	NUM
biomedich-899	90	2	biology	biology	NOUN
biomedich-899	90	3	,	,	PUNCT
biomedich-899	90	4	medicine	medicine	NOUN
biomedich-899	90	5	,	,	PUNCT
biomedich-899	90	6	&	&	CCONJ
biomedich-899	90	7	natural	natural	ADJ
biomedich-899	90	8	product	product	NOUN
biomedich-899	90	9	chemistry	chemistry	NOUN
biomedich-899	90	10	14	14	NUM
biomedich-899	90	11	(	(	PUNCT
biomedich-899	90	12	2	2	NUM
biomedich-899	90	13	)	)	PUNCT
biomedich-899	90	14	,	,	PUNCT
biomedich-899	90	15	2025	2025	NUM
biomedich-899	90	16	:	:	PUNCT
biomedich-899	90	17	905	905	NUM
biomedich-899	90	18	-	-	SYM
biomedich-899	90	19	909	909	NUM
biomedich-899	90	20	figure	figure	NOUN
biomedich-899	90	21	3	3	NUM
biomedich-899	90	22	.	.	PUNCT
biomedich-899	90	23	reaction	reaction	NOUN
biomedich-899	90	24	scheme	scheme	NOUN
biomedich-899	90	25	of	of	ADP
biomedich-899	90	26	synthesis	synthesis	NOUN
biomedich-899	90	27	of	of	ADP
biomedich-899	90	28	naos	naos	PROPN
biomedich-899	90	29	-	-	PUNCT
biomedich-899	90	30	chitosan	chitosan	PROPN
biomedich-899	90	31	the	the	DET
biomedich-899	90	32	fourier	fourier	NOUN
biomedich-899	90	33	-	-	PUNCT
biomedich-899	90	34	transform	transform	NOUN
biomedich-899	90	35	infrared	infrared	NOUN
biomedich-899	90	36	(	(	PUNCT
biomedich-899	90	37	ftir	ftir	PROPN
biomedich-899	90	38	)	)	PUNCT
biomedich-899	90	39	spectra	spectra	NOUN
biomedich-899	90	40	(	(	PUNCT
biomedich-899	90	41	figure	figure	NOUN
biomedich-899	90	42	1	1	NUM
biomedich-899	90	43	)	)	PUNCT
biomedich-899	90	44	provide	provide	VERB
biomedich-899	90	45	critical	critical	ADJ
biomedich-899	90	46	evidence	evidence	NOUN
biomedich-899	90	47	supporting	support	VERB
biomedich-899	90	48	the	the	DET
biomedich-899	90	49	structural	structural	ADJ
biomedich-899	90	50	transformations	transformation	NOUN
biomedich-899	90	51	at	at	ADP
biomedich-899	90	52	each	each	DET
biomedich-899	90	53	step	step	NOUN
biomedich-899	90	54	of	of	ADP
biomedich-899	90	55	the	the	DET
biomedich-899	90	56	reaction	reaction	NOUN
biomedich-899	90	57	.	.	PUNCT
biomedich-899	91	1	the	the	DET
biomedich-899	91	2	characteristic	characteristic	ADJ
biomedich-899	91	3	absorption	absorption	NOUN
biomedich-899	91	4	bands	band	NOUN
biomedich-899	91	5	of	of	ADP
biomedich-899	91	6	chitosan	chitosan	NOUN
biomedich-899	91	7	were	be	AUX
biomedich-899	91	8	observed	observe	VERB
biomedich-899	91	9	at	at	ADP
biomedich-899	91	10	3400–3200	3400–3200	NUM
biomedich-899	91	11	cm⁻¹	cm⁻¹	NOUN
biomedich-899	91	12	,	,	PUNCT
biomedich-899	91	13	representing	represent	VERB
biomedich-899	91	14	o	o	NOUN
biomedich-899	91	15	–	–	PUNCT
biomedich-899	91	16	h	h	NOUN
biomedich-899	91	17	and	and	CCONJ
biomedich-899	91	18	n	n	CCONJ
biomedich-899	91	19	–	–	PUNCT
biomedich-899	91	20	h	h	NOUN
biomedich-899	91	21	stretching	stretch	VERB
biomedich-899	91	22	vibrations	vibration	NOUN
biomedich-899	91	23	,	,	PUNCT
biomedich-899	91	24	and	and	CCONJ
biomedich-899	91	25	at	at	ADP
biomedich-899	91	26	~1600	~1600	ADP
biomedich-899	91	27	cm⁻¹	cm⁻¹	NOUN
biomedich-899	91	28	,	,	PUNCT
biomedich-899	91	29	corresponding	correspond	VERB
biomedich-899	91	30	to	to	ADP
biomedich-899	91	31	n	n	CCONJ
biomedich-899	91	32	–	–	PUNCT
biomedich-899	91	33	h	h	NOUN
biomedich-899	91	34	bending	bend	VERB
biomedich-899	91	35	vibrations	vibration	NOUN
biomedich-899	91	36	.	.	PUNCT
biomedich-899	92	1	the	the	DET
biomedich-899	92	2	polysaccharide	polysaccharide	NOUN
biomedich-899	92	3	backbone	backbone	NOUN
biomedich-899	92	4	was	be	AUX
biomedich-899	92	5	further	far	ADV
biomedich-899	92	6	identified	identify	VERB
biomedich-899	92	7	through	through	ADP
biomedich-899	92	8	the	the	DET
biomedich-899	92	9	c	c	PROPN
biomedich-899	92	10	–	–	PUNCT
biomedich-899	92	11	o	o	NOUN
biomedich-899	92	12	stretching	stretch	VERB
biomedich-899	92	13	peaks	peak	NOUN
biomedich-899	92	14	at	at	ADP
biomedich-899	92	15	~1070	~1070	PUNCT
biomedich-899	92	16	and	and	CCONJ
biomedich-899	92	17	~1020	~1020	NUM
biomedich-899	92	18	cm⁻¹.	cm⁻¹.	VERB
biomedich-899	92	19	the	the	DET
biomedich-899	92	20	introduction	introduction	NOUN
biomedich-899	92	21	of	of	ADP
biomedich-899	92	22	sulfate	sulfate	NOUN
biomedich-899	92	23	groups	group	NOUN
biomedich-899	92	24	was	be	AUX
biomedich-899	92	25	confirmed	confirm	VERB
biomedich-899	92	26	by	by	ADP
biomedich-899	92	27	the	the	DET
biomedich-899	92	28	appearance	appearance	NOUN
biomedich-899	92	29	of	of	ADP
biomedich-899	92	30	new	new	ADJ
biomedich-899	92	31	absorption	absorption	NOUN
biomedich-899	92	32	bands	band	NOUN
biomedich-899	92	33	at	at	ADP
biomedich-899	92	34	~1250	~1250	NUM
biomedich-899	92	35	cm⁻¹	cm⁻¹	NOUN
biomedich-899	92	36	and	and	CCONJ
biomedich-899	92	37	~1025	~1025	PROPN
biomedich-899	92	38	cm⁻¹	cm⁻¹	PROPN
biomedich-899	92	39	,	,	PUNCT
biomedich-899	92	40	assigned	assign	VERB
biomedich-899	92	41	to	to	ADP
biomedich-899	92	42	s	s	NOUN
biomedich-899	92	43	=	=	NOUN
biomedich-899	92	44	o	o	NOUN
biomedich-899	92	45	and	and	CCONJ
biomedich-899	92	46	c	c	X
biomedich-899	92	47	–	–	PUNCT
biomedich-899	92	48	o	o	NOUN
biomedich-899	92	49	–	–	PUNCT
biomedich-899	92	50	s	s	VERB
biomedich-899	92	51	stretching	stretch	VERB
biomedich-899	92	52	vibrations	vibration	NOUN
biomedich-899	92	53	,	,	PUNCT
biomedich-899	92	54	respectively	respectively	ADV
biomedich-899	92	55	.	.	PUNCT
biomedich-899	93	1	the	the	DET
biomedich-899	93	2	reduced	reduced	ADJ
biomedich-899	93	3	intensity	intensity	NOUN
biomedich-899	93	4	of	of	ADP
biomedich-899	93	5	the	the	DET
biomedich-899	93	6	o	o	NOUN
biomedich-899	93	7	–	–	PUNCT
biomedich-899	93	8	h	h	NOUN
biomedich-899	93	9	stretching	stretch	VERB
biomedich-899	93	10	band	band	NOUN
biomedich-899	93	11	supports	support	VERB
biomedich-899	93	12	the	the	DET
biomedich-899	93	13	substitution	substitution	NOUN
biomedich-899	93	14	of	of	ADP
biomedich-899	93	15	hydroxyl	hydroxyl	NOUN
biomedich-899	93	16	groups	group	NOUN
biomedich-899	93	17	by	by	ADP
biomedich-899	93	18	sulfate	sulfate	NOUN
biomedich-899	93	19	groups	group	NOUN
biomedich-899	93	20	.	.	PUNCT
biomedich-899	94	1	the	the	DET
biomedich-899	94	2	imination	imination	NOUN
biomedich-899	94	3	step	step	NOUN
biomedich-899	94	4	was	be	AUX
biomedich-899	94	5	evidenced	evidence	VERB
biomedich-899	94	6	by	by	ADP
biomedich-899	94	7	the	the	DET
biomedich-899	94	8	emergence	emergence	NOUN
biomedich-899	94	9	of	of	ADP
biomedich-899	94	10	a	a	DET
biomedich-899	94	11	new	new	ADJ
biomedich-899	94	12	absorption	absorption	NOUN
biomedich-899	94	13	band	band	NOUN
biomedich-899	94	14	at	at	ADP
biomedich-899	94	15	~1650	~1650	ADP
biomedich-899	94	16	cm⁻¹	cm⁻¹	NOUN
biomedich-899	94	17	,	,	PUNCT
biomedich-899	94	18	attributed	attribute	VERB
biomedich-899	94	19	to	to	ADP
biomedich-899	94	20	the	the	DET
biomedich-899	94	21	c	c	NOUN
biomedich-899	94	22	=	=	NOUN
biomedich-899	94	23	n	n	NOUN
biomedich-899	94	24	stretching	stretch	VERB
biomedich-899	94	25	vibration	vibration	NOUN
biomedich-899	94	26	of	of	ADP
biomedich-899	94	27	the	the	DET
biomedich-899	94	28	imine	imine	ADJ
biomedich-899	94	29	bond	bond	NOUN
biomedich-899	94	30	.	.	PUNCT
biomedich-899	95	1	additionally	additionally	ADV
biomedich-899	95	2	,	,	PUNCT
biomedich-899	95	3	the	the	DET
biomedich-899	95	4	presence	presence	NOUN
biomedich-899	95	5	of	of	ADP
biomedich-899	95	6	an	an	DET
biomedich-899	95	7	aromatic	aromatic	ADJ
biomedich-899	95	8	c	c	NOUN
biomedich-899	95	9	=	=	X
biomedich-899	95	10	c	c	NOUN
biomedich-899	95	11	stretching	stretch	VERB
biomedich-899	95	12	band	band	NOUN
biomedich-899	95	13	at	at	ADP
biomedich-899	95	14	~1500	~1500	NUM
biomedich-899	95	15	cm⁻¹	cm⁻¹	NOUN
biomedich-899	95	16	confirms	confirm	VERB
biomedich-899	95	17	the	the	DET
biomedich-899	95	18	incorporation	incorporation	NOUN
biomedich-899	95	19	of	of	ADP
biomedich-899	95	20	the	the	DET
biomedich-899	95	21	aromatic	aromatic	ADJ
biomedich-899	95	22	p	p	NOUN
biomedich-899	95	23	-	-	PUNCT
biomedich-899	95	24	anisaldehyde	anisaldehyde	NOUN
biomedich-899	95	25	group	group	NOUN
biomedich-899	95	26	.	.	PUNCT
biomedich-899	96	1	importantly	importantly	ADV
biomedich-899	96	2	,	,	PUNCT
biomedich-899	96	3	the	the	DET
biomedich-899	96	4	sulfate	sulfate	NOUN
biomedich-899	96	5	-	-	PUNCT
biomedich-899	96	6	specific	specific	ADJ
biomedich-899	96	7	bands	band	NOUN
biomedich-899	96	8	at	at	ADP
biomedich-899	96	9	~1250	~1250	NUM
biomedich-899	96	10	cm⁻¹	cm⁻¹	NOUN
biomedich-899	96	11	and	and	CCONJ
biomedich-899	96	12	~1025	~1025	PROPN
biomedich-899	96	13	cm⁻¹	cm⁻¹	NOUN
biomedich-899	96	14	remain	remain	VERB
biomedich-899	96	15	visible	visible	ADJ
biomedich-899	96	16	,	,	PUNCT
biomedich-899	96	17	indicating	indicate	VERB
biomedich-899	96	18	the	the	DET
biomedich-899	96	19	preservation	preservation	NOUN
biomedich-899	96	20	of	of	ADP
biomedich-899	96	21	sulfation	sulfation	NOUN
biomedich-899	96	22	after	after	ADP
biomedich-899	96	23	schiff	schiff	NOUN
biomedich-899	96	24	base	base	NOUN
biomedich-899	96	25	formation	formation	NOUN
biomedich-899	96	26	.	.	PUNCT
biomedich-899	97	1	the	the	DET
biomedich-899	97	2	structural	structural	ADJ
biomedich-899	97	3	changes	change	NOUN
biomedich-899	97	4	were	be	AUX
biomedich-899	97	5	further	far	ADV
biomedich-899	97	6	validated	validate	VERB
biomedich-899	97	7	by	by	ADP
biomedich-899	97	8	¹h	¹h	ADJ
biomedich-899	97	9	nmr	nmr	NOUN
biomedich-899	97	10	spectroscopy	spectroscopy	NOUN
biomedich-899	97	11	,	,	PUNCT
biomedich-899	97	12	which	which	PRON
biomedich-899	97	13	provided	provide	VERB
biomedich-899	97	14	insight	insight	NOUN
biomedich-899	97	15	into	into	ADP
biomedich-899	97	16	the	the	DET
biomedich-899	97	17	chemical	chemical	NOUN
biomedich-899	97	18	environment	environment	NOUN
biomedich-899	97	19	of	of	ADP
biomedich-899	97	20	the	the	DET
biomedich-899	97	21	protons	proton	NOUN
biomedich-899	97	22	in	in	ADP
biomedich-899	97	23	the	the	DET
biomedich-899	97	24	chitosan	chitosan	ADJ
biomedich-899	97	25	derivative	derivative	NOUN
biomedich-899	97	26	.	.	PUNCT
biomedich-899	98	1	signals	signal	NOUN
biomedich-899	98	2	corresponding	correspond	VERB
biomedich-899	98	3	to	to	ADP
biomedich-899	98	4	the	the	DET
biomedich-899	98	5	glucosamine	glucosamine	NOUN
biomedich-899	98	6	ring	ring	NOUN
biomedich-899	98	7	protons	proton	NOUN
biomedich-899	98	8	were	be	AUX
biomedich-899	98	9	identified	identify	VERB
biomedich-899	98	10	,	,	PUNCT
biomedich-899	98	11	with	with	ADP
biomedich-899	98	12	h-1	h-1	NOUN
biomedich-899	98	13	appearing	appear	VERB
biomedich-899	98	14	at	at	ADP
biomedich-899	98	15	~5.0	~5.0	NOUN
biomedich-899	98	16	ppm	ppm	NOUN
biomedich-899	98	17	and	and	CCONJ
biomedich-899	98	18	the	the	DET
biomedich-899	98	19	other	other	ADJ
biomedich-899	98	20	protons	proton	NOUN
biomedich-899	98	21	(	(	PUNCT
biomedich-899	98	22	h-2	h-2	NOUN
biomedich-899	98	23	to	to	ADP
biomedich-899	98	24	h-6	h-6	VERB
biomedich-899	98	25	)	)	PUNCT
biomedich-899	98	26	resonating	resonate	VERB
biomedich-899	98	27	between	between	ADP
biomedich-899	98	28	3.0–4.0	3.0–4.0	NUM
biomedich-899	98	29	ppm	ppm	NOUN
biomedich-899	98	30	.	.	PUNCT
biomedich-899	99	1	the	the	DET
biomedich-899	99	2	sulfation	sulfation	NOUN
biomedich-899	99	3	step	step	NOUN
biomedich-899	99	4	induced	induce	VERB
biomedich-899	99	5	deshielding	deshielding	NOUN
biomedich-899	99	6	effects	effect	NOUN
biomedich-899	99	7	,	,	PUNCT
biomedich-899	99	8	resulting	result	VERB
biomedich-899	99	9	in	in	ADP
biomedich-899	99	10	the	the	DET
biomedich-899	99	11	appearance	appearance	NOUN
biomedich-899	99	12	of	of	ADP
biomedich-899	99	13	new	new	ADJ
biomedich-899	99	14	signals	signal	NOUN
biomedich-899	99	15	at	at	ADP
biomedich-899	99	16	~3.5	~3.5	NUM
biomedich-899	99	17	ppm	ppm	NOUN
biomedich-899	99	18	,	,	PUNCT
biomedich-899	99	19	corresponding	correspond	VERB
biomedich-899	99	20	to	to	ADP
biomedich-899	99	21	protons	proton	NOUN
biomedich-899	99	22	adjacent	adjacent	ADJ
biomedich-899	99	23	to	to	ADP
biomedich-899	99	24	the	the	DET
biomedich-899	99	25	introduced	introduce	VERB
biomedich-899	99	26	sulfate	sulfate	NOUN
biomedich-899	99	27	groups	group	NOUN
biomedich-899	99	28	.	.	PUNCT
biomedich-899	100	1	the	the	DET
biomedich-899	100	2	imine	imine	ADJ
biomedich-899	100	3	proton	proton	NOUN
biomedich-899	100	4	(	(	PUNCT
biomedich-899	100	5	c	c	NOUN
biomedich-899	100	6	=	=	SYM
biomedich-899	100	7	n	n	CCONJ
biomedich-899	100	8	–	–	PUNCT
biomedich-899	100	9	h	h	NOUN
biomedich-899	100	10	)	)	PUNCT
biomedich-899	100	11	was	be	AUX
biomedich-899	100	12	detected	detect	VERB
biomedich-899	100	13	as	as	ADP
biomedich-899	100	14	a	a	DET
biomedich-899	100	15	distinct	distinct	ADJ
biomedich-899	100	16	signal	signal	NOUN
biomedich-899	100	17	at	at	ADP
biomedich-899	100	18	~8.0–9.0	~8.0–9.0	NOUN
biomedich-899	100	19	ppm	ppm	ADJ
biomedich-899	100	20	,	,	PUNCT
biomedich-899	100	21	confirming	confirm	VERB
biomedich-899	100	22	the	the	DET
biomedich-899	100	23	formation	formation	NOUN
biomedich-899	100	24	of	of	ADP
biomedich-899	100	25	the	the	DET
biomedich-899	100	26	imine	imine	ADJ
biomedich-899	100	27	bond	bond	NOUN
biomedich-899	100	28	.	.	PUNCT
biomedich-899	101	1	the	the	DET
biomedich-899	101	2	aromatic	aromatic	ADJ
biomedich-899	101	3	protons	proton	NOUN
biomedich-899	101	4	of	of	ADP
biomedich-899	101	5	the	the	DET
biomedich-899	101	6	p	p	NOUN
biomedich-899	101	7	-	-	PUNCT
biomedich-899	101	8	anisaldehyde	anisaldehyde	NOUN
biomedich-899	101	9	group	group	NOUN
biomedich-899	101	10	were	be	AUX
biomedich-899	101	11	observed	observe	VERB
biomedich-899	101	12	as	as	ADP
biomedich-899	101	13	multiplets	multiplet	NOUN
biomedich-899	101	14	in	in	ADP
biomedich-899	101	15	the	the	DET
biomedich-899	101	16	region	region	NOUN
biomedich-899	101	17	of	of	ADP
biomedich-899	101	18	~6.5–7.5	~6.5–7.5	PROPN
biomedich-899	101	19	ppm	ppm	NOUN
biomedich-899	101	20	,	,	PUNCT
biomedich-899	101	21	consistent	consistent	ADJ
biomedich-899	101	22	with	with	ADP
biomedich-899	101	23	the	the	DET
biomedich-899	101	24	structure	structure	NOUN
biomedich-899	101	25	of	of	ADP
biomedich-899	101	26	the	the	DET
biomedich-899	101	27	attached	attached	ADJ
biomedich-899	101	28	aromatic	aromatic	ADJ
biomedich-899	101	29	group	group	NOUN
biomedich-899	101	30	.	.	PUNCT
biomedich-899	102	1	the	the	DET
biomedich-899	102	2	nmr	nmr	NOUN
biomedich-899	102	3	spectrum	spectrum	NOUN
biomedich-899	102	4	of	of	ADP
biomedich-899	102	5	the	the	DET
biomedich-899	102	6	final	final	ADJ
biomedich-899	102	7	product	product	NOUN
biomedich-899	102	8	showed	show	VERB
biomedich-899	102	9	overlapping	overlap	VERB
biomedich-899	102	10	signals	signal	NOUN
biomedich-899	102	11	from	from	ADP
biomedich-899	102	12	both	both	CCONJ
biomedich-899	102	13	the	the	DET
biomedich-899	102	14	sulfation	sulfation	NOUN
biomedich-899	102	15	and	and	CCONJ
biomedich-899	102	16	imination	imination	NOUN
biomedich-899	102	17	steps	step	NOUN
biomedich-899	102	18	.	.	PUNCT
biomedich-899	103	1	the	the	DET
biomedich-899	103	2	retention	retention	NOUN
biomedich-899	103	3	of	of	ADP
biomedich-899	103	4	sulfate	sulfate	NOUN
biomedich-899	103	5	-	-	PUNCT
biomedich-899	103	6	specific	specific	ADJ
biomedich-899	103	7	peaks	peak	NOUN
biomedich-899	103	8	and	and	CCONJ
biomedich-899	103	9	the	the	DET
biomedich-899	103	10	presence	presence	NOUN
biomedich-899	103	11	of	of	ADP
biomedich-899	103	12	the	the	DET
biomedich-899	103	13	aromatic	aromatic	ADJ
biomedich-899	103	14	imine	imine	NOUN
biomedich-899	103	15	signals	signal	NOUN
biomedich-899	103	16	confirm	confirm	VERB
biomedich-899	103	17	the	the	DET
biomedich-899	103	18	successful	successful	ADJ
biomedich-899	103	19	synthesis	synthesis	NOUN
biomedich-899	103	20	of	of	ADP
biomedich-899	103	21	the	the	DET
biomedich-899	103	22	amphiphilic	amphiphilic	ADJ
biomedich-899	103	23	chitosan	chitosan	NOUN
biomedich-899	103	24	derivative	derivative	NOUN
biomedich-899	103	25	.	.	PUNCT
biomedich-899	104	1	the	the	DET
biomedich-899	104	2	degree	degree	NOUN
biomedich-899	104	3	of	of	ADP
biomedich-899	104	4	substitution	substitution	NOUN
biomedich-899	104	5	(	(	PUNCT
biomedich-899	104	6	ds	ds	NOUN
biomedich-899	104	7	)	)	PUNCT
biomedich-899	104	8	of	of	ADP
biomedich-899	104	9	chitosan	chitosan	NOUN
biomedich-899	104	10	derivatives	derivative	NOUN
biomedich-899	104	11	was	be	AUX
biomedich-899	104	12	calculated	calculate	VERB
biomedich-899	104	13	using	use	VERB
biomedich-899	104	14	the	the	DET
biomedich-899	104	15	integration	integration	NOUN
biomedich-899	104	16	of	of	ADP
biomedich-899	104	17	nmr	nmr	NOUN
biomedich-899	104	18	peaks	peak	NOUN
biomedich-899	104	19	as	as	SCONJ
biomedich-899	104	20	shown	show	VERB
biomedich-899	104	21	in	in	ADP
biomedich-899	104	22	equation	equation	NOUN
biomedich-899	104	23	(	(	PUNCT
biomedich-899	104	24	1	1	NUM
biomedich-899	104	25	)	)	PUNCT
biomedich-899	104	26	.	.	PUNCT
biomedich-899	105	1	the	the	DET
biomedich-899	105	2	equation	equation	NOUN
biomedich-899	105	3	quantifies	quantify	VERB
biomedich-899	105	4	the	the	DET
biomedich-899	105	5	degree	degree	NOUN
biomedich-899	105	6	to	to	PART
biomedich-899	105	7	which	which	PRON
biomedich-899	105	8	anisaldehyde	anisaldehyde	NOUN
biomedich-899	105	9	groups	group	NOUN
biomedich-899	105	10	have	have	AUX
biomedich-899	105	11	been	be	AUX
biomedich-899	105	12	grafted	graft	VERB
biomedich-899	105	13	or	or	CCONJ
biomedich-899	105	14	chemically	chemically	ADV
biomedich-899	105	15	attached	attach	VERB
biomedich-899	105	16	to	to	ADP
biomedich-899	105	17	the	the	DET
biomedich-899	105	18	chitosan	chitosan	ADJ
biomedich-899	105	19	backbone	backbone	NOUN
biomedich-899	105	20	.	.	PUNCT
biomedich-899	106	1	the	the	DET
biomedich-899	106	2	numerator	numerator	NOUN
biomedich-899	106	3	sums	sum	VERB
biomedich-899	106	4	up	up	ADP
biomedich-899	106	5	the	the	DET
biomedich-899	106	6	integral	integral	ADJ
biomedich-899	106	7	values	value	NOUN
biomedich-899	106	8	of	of	ADP
biomedich-899	106	9	anisaldehyde	anisaldehyde	NOUN
biomedich-899	106	10	-	-	PUNCT
biomedich-899	106	11	specific	specific	ADJ
biomedich-899	106	12	protons	proton	NOUN
biomedich-899	106	13	,	,	PUNCT
biomedich-899	106	14	indicating	indicate	VERB
biomedich-899	106	15	the	the	DET
biomedich-899	106	16	amount	amount	NOUN
biomedich-899	106	17	of	of	ADP
biomedich-899	106	18	anisaldehyde	anisaldehyde	NOUN
biomedich-899	106	19	bound	bind	VERB
biomedich-899	106	20	to	to	ADP
biomedich-899	106	21	the	the	DET
biomedich-899	106	22	chitosan	chitosan	NOUN
biomedich-899	106	23	.	.	PUNCT
biomedich-899	107	1	the	the	DET
biomedich-899	107	2	denominator	denominator	NOUN
biomedich-899	107	3	normalizes	normalize	VERB
biomedich-899	107	4	this	this	DET
biomedich-899	107	5	value	value	NOUN
biomedich-899	107	6	based	base	VERB
biomedich-899	107	7	on	on	ADP
biomedich-899	107	8	the	the	DET
biomedich-899	107	9	reference	reference	NOUN
biomedich-899	107	10	signal	signal	NOUN
biomedich-899	107	11	of	of	ADP
biomedich-899	107	12	the	the	DET
biomedich-899	107	13	chitosan	chitosan	ADJ
biomedich-899	107	14	backbone	backbone	NOUN
biomedich-899	107	15	,	,	PUNCT
biomedich-899	107	16	ensuring	ensure	VERB
biomedich-899	107	17	that	that	SCONJ
biomedich-899	107	18	the	the	DET
biomedich-899	107	19	calculation	calculation	NOUN
biomedich-899	107	20	accounts	account	VERB
biomedich-899	107	21	for	for	ADP
biomedich-899	107	22	the	the	DET
biomedich-899	107	23	number	number	NOUN
biomedich-899	107	24	of	of	ADP
biomedich-899	107	25	available	available	ADJ
biomedich-899	107	26	reactive	reactive	ADJ
biomedich-899	107	27	sites	site	NOUN
biomedich-899	107	28	(	(	PUNCT
biomedich-899	107	29	proton	proton	NOUN
biomedich-899	107	30	equivalent	equivalent	NOUN
biomedich-899	107	31	)	)	PUNCT
biomedich-899	107	32	.	.	PUNCT
biomedich-899	108	1	the	the	DET
biomedich-899	108	2	table	table	NOUN
biomedich-899	108	3	shows	show	VERB
biomedich-899	108	4	the	the	DET
biomedich-899	108	5	degree	degree	NOUN
biomedich-899	108	6	of	of	ADP
biomedich-899	108	7	substitution	substitution	NOUN
biomedich-899	108	8	(	(	PUNCT
biomedich-899	108	9	ds	ds	ADJ
biomedich-899	108	10	)	)	PUNCT
biomedich-899	108	11	results	result	NOUN
biomedich-899	108	12	for	for	ADP
biomedich-899	108	13	a	a	DET
biomedich-899	108	14	chitosan	chitosan	ADJ
biomedich-899	108	15	derivative	derivative	NOUN
biomedich-899	108	16	substituted	substitute	VERB
biomedich-899	108	17	with	with	ADP
biomedich-899	108	18	anisaldehyde	anisaldehyde	NOUN
biomedich-899	108	19	.	.	PUNCT
biomedich-899	109	1	the	the	DET
biomedich-899	109	2	results	result	NOUN
biomedich-899	109	3	are	be	AUX
biomedich-899	109	4	presented	present	VERB
biomedich-899	109	5	for	for	ADP
biomedich-899	109	6	two	two	NUM
biomedich-899	109	7	different	different	ADJ
biomedich-899	109	8	molar	molar	ADJ
biomedich-899	109	9	ratios	ratio	NOUN
biomedich-899	109	10	of	of	ADP
biomedich-899	109	11	aldehyde	aldehyde	NOUN
biomedich-899	109	12	to	to	ADP
biomedich-899	109	13	amino	amino	ADJ
biomedich-899	109	14	groups	group	NOUN
biomedich-899	109	15	in	in	ADP
biomedich-899	109	16	chitosan	chitosan	NOUN
biomedich-899	109	17	.	.	PUNCT
biomedich-899	110	1	the	the	DET
biomedich-899	110	2	data	datum	NOUN
biomedich-899	110	3	clearly	clearly	ADV
biomedich-899	110	4	show	show	VERB
biomedich-899	110	5	that	that	SCONJ
biomedich-899	110	6	increasing	increase	VERB
biomedich-899	110	7	the	the	DET
biomedich-899	110	8	molar	molar	ADJ
biomedich-899	110	9	ratio	ratio	NOUN
biomedich-899	110	10	of	of	ADP
biomedich-899	110	11	anisaldehyde	anisaldehyde	NOUN
biomedich-899	110	12	to	to	ADP
biomedich-899	110	13	amino	amino	NOUN
biomedich-899	110	14	groups	group	NOUN
biomedich-899	110	15	enhances	enhance	VERB
biomedich-899	110	16	the	the	DET
biomedich-899	110	17	degree	degree	NOUN
biomedich-899	110	18	of	of	ADP
biomedich-899	110	19	substitution	substitution	NOUN
biomedich-899	110	20	,	,	PUNCT
biomedich-899	110	21	as	as	SCONJ
biomedich-899	110	22	evidenced	evidence	VERB
biomedich-899	110	23	by	by	ADP
biomedich-899	110	24	the	the	DET
biomedich-899	110	25	higher	high	ADJ
biomedich-899	110	26	ds	ds	ADJ
biomedich-899	110	27	value	value	NOUN
biomedich-899	110	28	for	for	ADP
biomedich-899	110	29	the	the	DET
biomedich-899	110	30	3:1	3:1	NUM
biomedich-899	110	31	ratio	ratio	NOUN
biomedich-899	110	32	compared	compare	VERB
biomedich-899	110	33	to	to	ADP
biomedich-899	110	34	the	the	DET
biomedich-899	110	35	1:1	1:1	NUM
biomedich-899	110	36	ratio	ratio	NOUN
biomedich-899	110	37	.	.	PUNCT
biomedich-899	111	1	this	this	PRON
biomedich-899	111	2	suggests	suggest	VERB
biomedich-899	111	3	that	that	SCONJ
biomedich-899	111	4	the	the	DET
biomedich-899	111	5	availability	availability	NOUN
biomedich-899	111	6	of	of	ADP
biomedich-899	111	7	anisaldehyde	anisaldehyde	NOUN
biomedich-899	111	8	molecules	molecule	NOUN
biomedich-899	111	9	relative	relative	ADJ
biomedich-899	111	10	to	to	ADP
biomedich-899	111	11	reactive	reactive	ADJ
biomedich-899	111	12	sites	site	NOUN
biomedich-899	111	13	on	on	ADP
biomedich-899	111	14	chitosan	chitosan	NOUN
biomedich-899	111	15	is	be	AUX
biomedich-899	111	16	a	a	DET
biomedich-899	111	17	critical	critical	ADJ
biomedich-899	111	18	factor	factor	NOUN
biomedich-899	111	19	in	in	ADP
biomedich-899	111	20	determining	determine	VERB
biomedich-899	111	21	the	the	DET
biomedich-899	111	22	extent	extent	NOUN
biomedich-899	111	23	of	of	ADP
biomedich-899	111	24	substitution	substitution	NOUN
biomedich-899	111	25	.	.	PUNCT
biomedich-899	112	1	the	the	DET
biomedich-899	112	2	ftir	ftir	PROPN
biomedich-899	112	3	and	and	CCONJ
biomedich-899	112	4	nmr	nmr	NOUN
biomedich-899	112	5	spectra	spectra	PROPN
biomedich-899	112	6	provide	provide	VERB
biomedich-899	112	7	conclusive	conclusive	ADJ
biomedich-899	112	8	evidence	evidence	NOUN
biomedich-899	112	9	of	of	ADP
biomedich-899	112	10	the	the	DET
biomedich-899	112	11	successful	successful	ADJ
biomedich-899	112	12	sequential	sequential	ADJ
biomedich-899	112	13	modification	modification	NOUN
biomedich-899	112	14	of	of	ADP
biomedich-899	112	15	chitosan	chitosan	NOUN
biomedich-899	112	16	.	.	PUNCT
biomedich-899	113	1	the	the	DET
biomedich-899	113	2	structural	structural	ADJ
biomedich-899	113	3	features	feature	NOUN
biomedich-899	113	4	introduced	introduce	VERB
biomedich-899	113	5	during	during	ADP
biomedich-899	113	6	sulfation	sulfation	NOUN
biomedich-899	113	7	and	and	CCONJ
biomedich-899	113	8	schiff	schiff	NOUN
biomedich-899	113	9	base	base	NOUN
biomedich-899	113	10	formation	formation	NOUN
biomedich-899	113	11	are	be	AUX
biomedich-899	113	12	clearly	clearly	ADV
biomedich-899	113	13	reflected	reflect	VERB
biomedich-899	113	14	in	in	ADP
biomedich-899	113	15	the	the	DET
biomedich-899	113	16	spectral	spectral	ADJ
biomedich-899	113	17	data	data	PROPN
biomedich-899	113	18	,	,	PUNCT
biomedich-899	113	19	supporting	support	VERB
biomedich-899	113	20	the	the	DET
biomedich-899	113	21	chemical	chemical	NOUN
biomedich-899	113	22	integrity	integrity	NOUN
biomedich-899	113	23	of	of	ADP
biomedich-899	113	24	the	the	DET
biomedich-899	113	25	final	final	ADJ
biomedich-899	113	26	product	product	NOUN
biomedich-899	113	27	.	.	PUNCT
biomedich-899	114	1	the	the	DET
biomedich-899	114	2	presence	presence	NOUN
biomedich-899	114	3	of	of	ADP
biomedich-899	114	4	both	both	DET
biomedich-899	114	5	hydrophilic	hydrophilic	ADJ
biomedich-899	114	6	sulfate	sulfate	NOUN
biomedich-899	114	7	and	and	CCONJ
biomedich-899	114	8	hydrophobic	hydrophobic	NOUN
biomedich-899	114	9	aromatic	aromatic	ADJ
biomedich-899	114	10	groups	group	NOUN
biomedich-899	114	11	substantiates	substantiate	VERB
biomedich-899	114	12	the	the	DET
biomedich-899	114	13	amphiphilic	amphiphilic	ADJ
biomedich-899	114	14	nature	nature	NOUN
biomedich-899	114	15	of	of	ADP
biomedich-899	114	16	the	the	DET
biomedich-899	114	17	synthesized	synthesize	VERB
biomedich-899	114	18	derivative	derivative	NOUN
biomedich-899	114	19	.	.	PUNCT
biomedich-899	115	1	the	the	DET
biomedich-899	115	2	amphiphilic	amphiphilic	ADJ
biomedich-899	115	3	behavior	behavior	NOUN
biomedich-899	115	4	of	of	ADP
biomedich-899	115	5	naos	naos	PROPN
biomedich-899	115	6	-	-	PUNCT
biomedich-899	115	7	chitosan	chitosan	PROPN
biomedich-899	115	8	was	be	AUX
biomedich-899	115	9	evaluated	evaluate	VERB
biomedich-899	115	10	by	by	ADP
biomedich-899	115	11	determining	determine	VERB
biomedich-899	115	12	its	its	PRON
biomedich-899	115	13	critical	critical	ADJ
biomedich-899	115	14	micelle	micelle	NOUN
biomedich-899	115	15	concentration	concentration	NOUN
biomedich-899	115	16	(	(	PUNCT
biomedich-899	115	17	cmc	cmc	NOUN
biomedich-899	115	18	)	)	PUNCT
biomedich-899	115	19	,	,	PUNCT
biomedich-899	115	20	as	as	SCONJ
biomedich-899	115	21	shown	show	VERB
biomedich-899	115	22	in	in	ADP
biomedich-899	115	23	figure	figure	NOUN
biomedich-899	115	24	2	2	NUM
biomedich-899	115	25	.	.	PUNCT
biomedich-899	116	1	the	the	DET
biomedich-899	116	2	cmc	cmc	NOUN
biomedich-899	116	3	is	be	AUX
biomedich-899	116	4	the	the	DET
biomedich-899	116	5	concentration	concentration	NOUN
biomedich-899	116	6	at	at	ADP
biomedich-899	116	7	which	which	PRON
biomedich-899	116	8	amphiphilic	amphiphilic	ADJ
biomedich-899	116	9	molecules	molecule	NOUN
biomedich-899	116	10	begin	begin	VERB
biomedich-899	116	11	to	to	PART
biomedich-899	116	12	self	self	NOUN
biomedich-899	116	13	-	-	PUNCT
biomedich-899	116	14	assemble	assemble	VERB
biomedich-899	116	15	into	into	ADP
biomedich-899	116	16	micelles	micelle	NOUN
biomedich-899	116	17	,	,	PUNCT
biomedich-899	116	18	a	a	DET
biomedich-899	116	19	key	key	ADJ
biomedich-899	116	20	property	property	NOUN
biomedich-899	116	21	for	for	ADP
biomedich-899	116	22	applications	application	NOUN
biomedich-899	116	23	in	in	ADP
biomedich-899	116	24	encapsulation	encapsulation	NOUN
biomedich-899	116	25	and	and	CCONJ
biomedich-899	116	26	delivery	delivery	NOUN
biomedich-899	116	27	systems	system	NOUN
biomedich-899	116	28	.	.	PUNCT
biomedich-899	117	1	the	the	DET
biomedich-899	117	2	graph	graph	NOUN
biomedich-899	117	3	for	for	ADP
biomedich-899	117	4	naos	naos	PROPN
biomedich-899	117	5	-	-	PUNCT
biomedich-899	117	6	chitosan	chitosan	PROPN
biomedich-899	117	7	shows	show	VERB
biomedich-899	117	8	a	a	DET
biomedich-899	117	9	gradual	gradual	ADJ
biomedich-899	117	10	increase	increase	NOUN
biomedich-899	117	11	in	in	ADP
biomedich-899	117	12	the	the	DET
biomedich-899	117	13	intensity	intensity	NOUN
biomedich-899	117	14	ratio	ratio	NOUN
biomedich-899	117	15	(	(	PUNCT
biomedich-899	117	16	i338	i338	PROPN
biomedich-899	117	17	/	/	SYM
biomedich-899	117	18	i372	i372	PROPN
biomedich-899	117	19	)	)	PUNCT
biomedich-899	117	20	as	as	ADP
biomedich-899	117	21	the	the	DET
biomedich-899	117	22	concentration	concentration	NOUN
biomedich-899	117	23	increases	increase	NOUN
biomedich-899	117	24	.	.	PUNCT
biomedich-899	118	1	the	the	DET
biomedich-899	118	2	intensity	intensity	NOUN
biomedich-899	118	3	ratio	ratio	NOUN
biomedich-899	118	4	remains	remain	VERB
biomedich-899	118	5	constant	constant	ADJ
biomedich-899	118	6	at	at	ADP
biomedich-899	118	7	approximately	approximately	ADV
biomedich-899	118	8	1.0	1.0	NUM
biomedich-899	118	9	.	.	PUNCT
biomedich-899	119	1	this	this	PRON
biomedich-899	119	2	suggests	suggest	VERB
biomedich-899	119	3	that	that	SCONJ
biomedich-899	119	4	naos	naos	PROPN
biomedich-899	119	5	-	-	PUNCT
biomedich-899	119	6	chitosan	chitosan	ADJ
biomedich-899	119	7	molecules	molecule	NOUN
biomedich-899	119	8	do	do	AUX
biomedich-899	119	9	not	not	PART
biomedich-899	119	10	aggregate	aggregate	VERB
biomedich-899	119	11	significantly	significantly	ADV
biomedich-899	119	12	in	in	ADP
biomedich-899	119	13	this	this	DET
biomedich-899	119	14	region	region	NOUN
biomedich-899	119	15	.	.	PUNCT
biomedich-899	120	1	the	the	DET
biomedich-899	120	2	ability	ability	NOUN
biomedich-899	120	3	of	of	ADP
biomedich-899	120	4	naos	naos	PROPN
biomedich-899	120	5	-	-	PUNCT
biomedich-899	120	6	chitosan	chitosan	PROPN
biomedich-899	120	7	to	to	PART
biomedich-899	120	8	exhibit	exhibit	VERB
biomedich-899	120	9	a	a	DET
biomedich-899	120	10	sharp	sharp	ADJ
biomedich-899	120	11	transition	transition	NOUN
biomedich-899	120	12	in	in	ADP
biomedich-899	120	13	intensity	intensity	NOUN
biomedich-899	120	14	ratio	ratio	NOUN
biomedich-899	120	15	confirms	confirm	VERB
biomedich-899	120	16	its	its	PRON
biomedich-899	120	17	amphiphilic	amphiphilic	ADJ
biomedich-899	120	18	nature	nature	NOUN
biomedich-899	120	19	.	.	PUNCT
biomedich-899	121	1	as	as	ADP
biomedich-899	121	2	concentration	concentration	NOUN
biomedich-899	121	3	increases	increase	NOUN
biomedich-899	121	4	,	,	PUNCT
biomedich-899	121	5	hydrophobic	hydrophobic	NOUN
biomedich-899	121	6	interactions	interaction	NOUN
biomedich-899	121	7	drive	drive	VERB
biomedich-899	121	8	the	the	DET
biomedich-899	121	9	formation	formation	NOUN
biomedich-899	121	10	of	of	ADP
biomedich-899	121	11	self	self	NOUN
biomedich-899	121	12	-	-	PUNCT
biomedich-899	121	13	assembled	assemble	VERB
biomedich-899	121	14	structures	structure	NOUN
biomedich-899	121	15	.	.	PUNCT
biomedich-899	122	1	this	this	DET
biomedich-899	122	2	trend	trend	NOUN
biomedich-899	122	3	indicates	indicate	VERB
biomedich-899	122	4	the	the	DET
biomedich-899	122	5	transition	transition	NOUN
biomedich-899	122	6	from	from	ADP
biomedich-899	122	7	individual	individual	ADJ
biomedich-899	122	8	amphiphilic	amphiphilic	ADJ
biomedich-899	122	9	molecules	molecule	NOUN
biomedich-899	122	10	to	to	PART
biomedich-899	122	11	micelle	micelle	NOUN
biomedich-899	122	12	formation	formation	NOUN
biomedich-899	122	13	.	.	PUNCT
biomedich-899	123	1	the	the	DET
biomedich-899	123	2	distinct	distinct	ADJ
biomedich-899	123	3	plateau	plateau	NOUN
biomedich-899	123	4	in	in	ADP
biomedich-899	123	5	intensity	intensity	NOUN
biomedich-899	123	6	ratio	ratio	PROPN
biomedich-899	123	7	herayati	herayati	PROPN
biomedich-899	123	8	et	et	PROPN
biomedich-899	123	9	al	al	PROPN
biomedich-899	123	10	.	.	PROPN
biomedich-899	123	11	–	–	PUNCT
biomedich-899	123	12	synthesis	synthesis	NOUN
biomedich-899	123	13	,	,	PUNCT
biomedich-899	123	14	characterization	characterization	NOUN
biomedich-899	123	15	,	,	PUNCT
biomedich-899	123	16	and	and	CCONJ
biomedich-899	123	17	micellar	micellar	ADJ
biomedich-899	123	18	behavior	behavior	NOUN
biomedich-899	123	19	of	of	ADP
biomedich-899	123	20	…	…	PUNCT
biomedich-899	123	21	909	909	NUM
biomedich-899	123	22	at	at	ADP
biomedich-899	123	23	higher	high	ADJ
biomedich-899	123	24	concentrations	concentration	NOUN
biomedich-899	123	25	suggests	suggest	VERB
biomedich-899	123	26	the	the	DET
biomedich-899	123	27	stability	stability	NOUN
biomedich-899	123	28	of	of	ADP
biomedich-899	123	29	these	these	DET
biomedich-899	123	30	self	self	NOUN
biomedich-899	123	31	-	-	PUNCT
biomedich-899	123	32	assembled	assemble	VERB
biomedich-899	123	33	structures	structure	NOUN
biomedich-899	123	34	,	,	PUNCT
biomedich-899	123	35	which	which	PRON
biomedich-899	123	36	is	be	AUX
biomedich-899	123	37	a	a	DET
biomedich-899	123	38	hallmark	hallmark	NOUN
biomedich-899	123	39	of	of	ADP
biomedich-899	123	40	amphiphilic	amphiphilic	ADJ
biomedich-899	123	41	compounds	compound	NOUN
biomedich-899	123	42	.	.	PUNCT
biomedich-899	124	1	the	the	DET
biomedich-899	124	2	critical	critical	ADJ
biomedich-899	124	3	micelle	micelle	NOUN
biomedich-899	124	4	concentration	concentration	NOUN
biomedich-899	124	5	(	(	PUNCT
biomedich-899	124	6	cmc	cmc	NOUN
biomedich-899	124	7	)	)	PUNCT
biomedich-899	124	8	of	of	ADP
biomedich-899	124	9	approximately	approximately	ADV
biomedich-899	124	10	0.1	0.1	NUM
biomedich-899	124	11	mg	mg	NUM
biomedich-899	124	12	/	/	SYM
biomedich-899	124	13	ml	ml	PROPN
biomedich-899	124	14	indicates	indicate	VERB
biomedich-899	124	15	promising	promising	ADJ
biomedich-899	124	16	potential	potential	NOUN
biomedich-899	124	17	for	for	ADP
biomedich-899	124	18	naos	naos	PROPN
biomedich-899	124	19	-	-	PUNCT
biomedich-899	124	20	chitosan	chitosan	PROPN
biomedich-899	124	21	as	as	ADP
biomedich-899	124	22	a	a	DET
biomedich-899	124	23	material	material	NOUN
biomedich-899	124	24	in	in	ADP
biomedich-899	124	25	cosmetic	cosmetic	ADJ
biomedich-899	124	26	or	or	CCONJ
biomedich-899	124	27	drug	drug	NOUN
biomedich-899	124	28	delivery	delivery	NOUN
biomedich-899	124	29	applications	application	NOUN
biomedich-899	124	30	.	.	PUNCT
biomedich-899	125	1	a	a	DET
biomedich-899	125	2	low	low	ADJ
biomedich-899	125	3	cmc	cmc	NOUN
biomedich-899	125	4	indicates	indicate	VERB
biomedich-899	125	5	that	that	SCONJ
biomedich-899	125	6	micelle	micelle	NOUN
biomedich-899	125	7	formation	formation	NOUN
biomedich-899	125	8	occurs	occur	VERB
biomedich-899	125	9	at	at	ADP
biomedich-899	125	10	a	a	DET
biomedich-899	125	11	relatively	relatively	ADV
biomedich-899	125	12	low	low	ADJ
biomedich-899	125	13	concentration	concentration	NOUN
biomedich-899	125	14	.	.	PUNCT
biomedich-899	126	1	the	the	DET
biomedich-899	126	2	amphiphilic	amphiphilic	ADJ
biomedich-899	126	3	behaviour	behaviour	NOUN
biomedich-899	126	4	of	of	ADP
biomedich-899	126	5	naos	naos	PROPN
biomedich-899	126	6	-	-	PUNCT
biomedich-899	126	7	chitosan	chitosan	PROPN
biomedich-899	126	8	(	(	PUNCT
biomedich-899	126	9	hydrophilic	hydrophilic	ADJ
biomedich-899	126	10	chitosan	chitosan	NOUN
biomedich-899	126	11	backbone	backbone	NOUN
biomedich-899	126	12	and	and	CCONJ
biomedich-899	126	13	hydrophobic	hydrophobic	NOUN
biomedich-899	126	14	anisaldehyde	anisaldehyde	NOUN
biomedich-899	126	15	modification	modification	NOUN
biomedich-899	126	16	)	)	PUNCT
biomedich-899	126	17	makes	make	VERB
biomedich-899	126	18	it	it	PRON
biomedich-899	126	19	ideal	ideal	ADJ
biomedich-899	126	20	for	for	ADP
biomedich-899	126	21	encapsulating	encapsulate	VERB
biomedich-899	126	22	hydrophobic	hydrophobic	NOUN
biomedich-899	126	23	active	active	ADJ
biomedich-899	126	24	ingredients	ingredient	NOUN
biomedich-899	126	25	(	(	PUNCT
biomedich-899	126	26	e.g.	e.g.	ADV
biomedich-899	126	27	,	,	PUNCT
biomedich-899	126	28	drugs	drug	NOUN
biomedich-899	126	29	,	,	PUNCT
biomedich-899	126	30	vitamins	vitamin	NOUN
biomedich-899	126	31	,	,	PUNCT
biomedich-899	126	32	essential	essential	ADJ
biomedich-899	126	33	oils	oil	NOUN
biomedich-899	126	34	)	)	PUNCT
biomedich-899	126	35	within	within	ADP
biomedich-899	126	36	micelles	micelle	NOUN
biomedich-899	126	37	.	.	PUNCT
biomedich-899	127	1	conclusions	conclusion	NOUN
biomedich-899	127	2	in	in	ADP
biomedich-899	127	3	this	this	DET
biomedich-899	127	4	study	study	NOUN
biomedich-899	127	5	,	,	PUNCT
biomedich-899	127	6	amphiphilic	amphiphilic	ADJ
biomedich-899	127	7	chitosan	chitosan	NOUN
biomedich-899	127	8	derivatives	derivative	NOUN
biomedich-899	127	9	bearing	bear	VERB
biomedich-899	127	10	sulfate	sulfate	NOUN
biomedich-899	127	11	and	and	CCONJ
biomedich-899	127	12	aromatic	aromatic	ADJ
biomedich-899	127	13	imine	imine	NOUN
biomedich-899	127	14	groups	group	NOUN
biomedich-899	127	15	were	be	AUX
biomedich-899	127	16	successfully	successfully	ADV
biomedich-899	127	17	synthesized	synthesize	VERB
biomedich-899	127	18	through	through	ADP
biomedich-899	127	19	a	a	DET
biomedich-899	127	20	two	two	NUM
biomedich-899	127	21	-	-	PUNCT
biomedich-899	127	22	step	step	NOUN
biomedich-899	127	23	functionalization	functionalization	NOUN
biomedich-899	127	24	process	process	NOUN
biomedich-899	127	25	.	.	PUNCT
biomedich-899	128	1	the	the	DET
biomedich-899	128	2	sulfation	sulfation	NOUN
biomedich-899	128	3	of	of	ADP
biomedich-899	128	4	chitosan	chitosan	NOUN
biomedich-899	128	5	and	and	CCONJ
biomedich-899	128	6	subsequent	subsequent	ADJ
biomedich-899	128	7	schiff	schiff	NOUN
biomedich-899	128	8	base	base	NOUN
biomedich-899	128	9	formation	formation	NOUN
biomedich-899	128	10	with	with	ADP
biomedich-899	128	11	p	p	NOUN
biomedich-899	128	12	-	-	PUNCT
biomedich-899	128	13	anisaldehyde	anisaldehyde	NOUN
biomedich-899	128	14	were	be	AUX
biomedich-899	128	15	confirmed	confirm	VERB
biomedich-899	128	16	by	by	ADP
biomedich-899	128	17	ftir	ftir	PROPN
biomedich-899	128	18	and	and	CCONJ
biomedich-899	128	19	1h	1h	NUM
biomedich-899	128	20	nmr	nmr	NOUN
biomedich-899	128	21	spectroscopy	spectroscopy	NOUN
biomedich-899	128	22	,	,	PUNCT
biomedich-899	128	23	which	which	PRON
biomedich-899	128	24	provided	provide	VERB
biomedich-899	128	25	clear	clear	ADJ
biomedich-899	128	26	evidence	evidence	NOUN
biomedich-899	128	27	of	of	ADP
biomedich-899	128	28	the	the	DET
biomedich-899	128	29	incorporation	incorporation	NOUN
biomedich-899	128	30	of	of	ADP
biomedich-899	128	31	sulfate	sulfate	NOUN
biomedich-899	128	32	and	and	CCONJ
biomedich-899	128	33	aromatic	aromatic	ADJ
biomedich-899	128	34	imine	imine	NOUN
biomedich-899	128	35	(	(	PUNCT
biomedich-899	128	36	c	c	NOUN
biomedich-899	128	37	=	=	SYM
biomedich-899	128	38	n	n	CCONJ
biomedich-899	128	39	)	)	PUNCT
biomedich-899	128	40	groups	group	NOUN
biomedich-899	128	41	.	.	PUNCT
biomedich-899	129	1	these	these	DET
biomedich-899	129	2	structural	structural	ADJ
biomedich-899	129	3	modifications	modification	NOUN
biomedich-899	129	4	enhanced	enhance	VERB
biomedich-899	129	5	the	the	DET
biomedich-899	129	6	amphiphilic	amphiphilic	ADJ
biomedich-899	129	7	nature	nature	NOUN
biomedich-899	129	8	of	of	ADP
biomedich-899	129	9	the	the	DET
biomedich-899	129	10	chitosan	chitosan	ADJ
biomedich-899	129	11	derivatives	derivative	NOUN
biomedich-899	129	12	.	.	PUNCT
biomedich-899	130	1	the	the	DET
biomedich-899	130	2	critical	critical	ADJ
biomedich-899	130	3	micelle	micelle	NOUN
biomedich-899	130	4	concentration	concentration	NOUN
biomedich-899	130	5	(	(	PUNCT
biomedich-899	130	6	cmc	cmc	NOUN
biomedich-899	130	7	)	)	PUNCT
biomedich-899	130	8	study	study	NOUN
biomedich-899	130	9	demonstrated	demonstrate	VERB
biomedich-899	130	10	that	that	SCONJ
biomedich-899	130	11	naos	naos	PROPN
biomedich-899	130	12	-	-	PUNCT
biomedich-899	130	13	chitosan	chitosan	PROPN
biomedich-899	130	14	forms	form	NOUN
biomedich-899	130	15	micelles	micelle	NOUN
biomedich-899	130	16	at	at	ADP
biomedich-899	130	17	low	low	ADJ
biomedich-899	130	18	concentrations	concentration	NOUN
biomedich-899	130	19	.	.	PUNCT
biomedich-899	131	1	this	this	DET
biomedich-899	131	2	micellar	micellar	ADJ
biomedich-899	131	3	behavior	behavior	NOUN
biomedich-899	131	4	highlights	highlight	VERB
biomedich-899	131	5	the	the	DET
biomedich-899	131	6	potential	potential	NOUN
biomedich-899	131	7	of	of	ADP
biomedich-899	131	8	the	the	DET
biomedich-899	131	9	synthesized	synthesize	VERB
biomedich-899	131	10	derivatives	derivative	NOUN
biomedich-899	131	11	for	for	ADP
biomedich-899	131	12	encapsulating	encapsulate	VERB
biomedich-899	131	13	hydrophobic	hydrophobic	NOUN
biomedich-899	131	14	molecules	molecule	NOUN
biomedich-899	131	15	,	,	PUNCT
biomedich-899	131	16	making	make	VERB
biomedich-899	131	17	them	they	PRON
biomedich-899	131	18	suitable	suitable	ADJ
biomedich-899	131	19	for	for	ADP
biomedich-899	131	20	applications	application	NOUN
biomedich-899	131	21	in	in	ADP
biomedich-899	131	22	drug	drug	NOUN
biomedich-899	131	23	or	or	CCONJ
biomedich-899	131	24	cosmetic	cosmetic	ADJ
biomedich-899	131	25	delivery	delivery	NOUN
biomedich-899	131	26	.	.	PUNCT
biomedich-899	132	1	acknowledgements	acknowledgement	NOUN
biomedich-899	132	2	:	:	PUNCT
biomedich-899	132	3	this	this	DET
biomedich-899	132	4	research	research	NOUN
biomedich-899	132	5	is	be	AUX
biomedich-899	132	6	supported	support	VERB
biomedich-899	132	7	by	by	ADP
biomedich-899	132	8	direktorat	direktorat	NOUN
biomedich-899	132	9	jendral	jendral	ADJ
biomedich-899	132	10	pendidikan	pendidikan	PROPN
biomedich-899	132	11	tinggi	tinggi	PROPN
biomedich-899	132	12	,	,	PUNCT
biomedich-899	132	13	riset	riset	PROPN
biomedich-899	132	14	,	,	PUNCT
biomedich-899	132	15	dan	dan	PROPN
biomedich-899	132	16	teknologi	teknologi	PROPN
biomedich-899	132	17	under	under	ADP
biomedich-899	132	18	research	research	NOUN
biomedich-899	132	19	grant	grant	NOUN
biomedich-899	132	20	:	:	PUNCT
biomedich-899	132	21	luaran	luaran	ADJ
biomedich-899	132	22	wajib	wajib	PROPN
biomedich-899	132	23	hibah	hibah	PROPN
biomedich-899	132	24	kemendiktisaintek	kemendiktisaintek	PROPN
biomedich-899	132	25	skema	skema	VERB
biomedich-899	132	26	penelitian	penelitian	PROPN
biomedich-899	132	27	dosen	dosen	PROPN
biomedich-899	132	28	pemula	pemula	PROPN
biomedich-899	132	29	(	(	PUNCT
biomedich-899	132	30	pdp	pdp	PROPN
biomedich-899	132	31	)	)	PUNCT
biomedich-899	132	32	tahun	tahun	PROPN
biomedich-899	132	33	2025	2025	NUM
biomedich-899	132	34	no	no	INTJ
biomedich-899	132	35	.	.	PUNCT
biomedich-899	133	1	kontrak	kontrak	PROPN
biomedich-899	133	2	1483bc	1483bc	PROPN
biomedich-899	133	3	/	/	SYM
biomedich-899	133	4	it9.2.1	it9.2.1	PROPN
biomedich-899	133	5	/	/	SYM
biomedich-899	133	6	pt.01.03/2025	pt.01.03/2025	NOUN
biomedich-899	133	7	.	.	PUNCT
biomedich-899	134	1	authors	author	NOUN
biomedich-899	134	2	’	'	PUNCT
biomedich-899	134	3	contributions	contribution	NOUN
biomedich-899	134	4	:	:	PUNCT
biomedich-899	134	5	herayati	herayati	PROPN
biomedich-899	134	6	&	&	CCONJ
biomedich-899	134	7	deana	deana	PROPN
biomedich-899	134	8	wahyuningrum	wahyuningrum	PROPN
biomedich-899	134	9	designed	design	VERB
biomedich-899	134	10	the	the	DET
biomedich-899	134	11	study	study	NOUN
biomedich-899	134	12	.	.	PUNCT
biomedich-899	135	1	herayati	herayati	NOUN
biomedich-899	135	2	carried	carry	VERB
biomedich-899	135	3	out	out	ADP
biomedich-899	135	4	the	the	DET
biomedich-899	135	5	laboratory	laboratory	NOUN
biomedich-899	135	6	work	work	NOUN
biomedich-899	135	7	.	.	PUNCT
biomedich-899	136	1	damar	damar	PROPN
biomedich-899	136	2	&	&	CCONJ
biomedich-899	136	3	indah	indah	PROPN
biomedich-899	136	4	analyzed	analyze	VERB
biomedich-899	136	5	the	the	DET
biomedich-899	136	6	data	datum	NOUN
biomedich-899	136	7	.	.	PUNCT
biomedich-899	137	1	herayati	herayati	PROPN
biomedich-899	137	2	wrote	write	VERB
biomedich-899	137	3	the	the	DET
biomedich-899	137	4	manuscript	manuscript	NOUN
biomedich-899	137	5	.	.	PUNCT
biomedich-899	138	1	all	all	DET
biomedich-899	138	2	authors	author	NOUN
biomedich-899	138	3	read	read	VERB
biomedich-899	138	4	and	and	CCONJ
biomedich-899	138	5	approved	approve	VERB
biomedich-899	138	6	the	the	DET
biomedich-899	138	7	final	final	ADJ
biomedich-899	138	8	version	version	NOUN
biomedich-899	138	9	of	of	ADP
biomedich-899	138	10	the	the	DET
biomedich-899	138	11	manuscript	manuscript	NOUN
biomedich-899	138	12	competing	compete	VERB
biomedich-899	138	13	interests	interest	NOUN
biomedich-899	138	14	:	:	PUNCT
biomedich-899	138	15	the	the	DET
biomedich-899	138	16	authors	author	NOUN
biomedich-899	138	17	declare	declare	VERB
biomedich-899	138	18	that	that	SCONJ
biomedich-899	138	19	there	there	PRON
biomedich-899	138	20	are	be	VERB
biomedich-899	138	21	no	no	DET
biomedich-899	138	22	competing	compete	VERB
biomedich-899	138	23	interests	interest	NOUN
biomedich-899	138	24	.	.	PUNCT
biomedich-899	139	1	references	reference	NOUN
biomedich-899	139	2	aguiar	aguiar	PROPN
biomedich-899	139	3	,	,	PUNCT
biomedich-899	139	4	j.	j.	PROPN
biomedich-899	139	5	,	,	PUNCT
biomedich-899	139	6	carpena	carpena	PROPN
biomedich-899	139	7	,	,	PUNCT
biomedich-899	139	8	p.	p.	PROPN
biomedich-899	139	9	,	,	PUNCT
biomedich-899	139	10	molina	molina	PROPN
biomedich-899	139	11	-	-	PUNCT
biomedich-899	139	12	bolı́var	bolı́var	PROPN
biomedich-899	139	13	,	,	PUNCT
biomedich-899	139	14	j.	j.	PROPN
biomedich-899	139	15	a.	a.	PROPN
biomedich-899	139	16	,	,	PUNCT
biomedich-899	139	17	&	&	CCONJ
biomedich-899	139	18	carnero	carnero	PROPN
biomedich-899	139	19	ruiz	ruiz	PROPN
biomedich-899	139	20	,	,	PUNCT
biomedich-899	139	21	c.	c.	PROPN
biomedich-899	139	22	(	(	PUNCT
biomedich-899	139	23	2003	2003	NUM
biomedich-899	139	24	)	)	PUNCT
biomedich-899	139	25	.	.	PUNCT
biomedich-899	140	1	on	on	ADP
biomedich-899	140	2	the	the	DET
biomedich-899	140	3	determination	determination	NOUN
biomedich-899	140	4	of	of	ADP
biomedich-899	140	5	the	the	DET
biomedich-899	140	6	critical	critical	ADJ
biomedich-899	140	7	micelle	micelle	NOUN
biomedich-899	140	8	concentration	concentration	NOUN
biomedich-899	140	9	by	by	ADP
biomedich-899	140	10	the	the	DET
biomedich-899	140	11	pyrene	pyrene	PROPN
biomedich-899	140	12	1:3	1:3	NUM
biomedich-899	140	13	ratio	ratio	NOUN
biomedich-899	140	14	method	method	NOUN
biomedich-899	140	15	.	.	PUNCT
biomedich-899	141	1	journal	journal	NOUN
biomedich-899	141	2	of	of	ADP
biomedich-899	141	3	colloid	colloid	NOUN
biomedich-899	141	4	and	and	CCONJ
biomedich-899	141	5	interface	interface	NOUN
biomedich-899	141	6	science	science	NOUN
biomedich-899	141	7	,	,	PUNCT
biomedich-899	141	8	258(1	258(1	NUM
biomedich-899	141	9	)	)	PUNCT
biomedich-899	141	10	,	,	PUNCT
biomedich-899	141	11	116–122	116–122	NUM
biomedich-899	141	12	.	.	PUNCT
biomedich-899	142	1	https://doi.org/10.1016/s0021-9797(02)00082-6	https://doi.org/10.1016/s0021-9797(02)00082-6	PROPN
biomedich-899	142	2	diab	diab	PROPN
biomedich-899	142	3	,	,	PUNCT
biomedich-899	142	4	m.	m.	NOUN
biomedich-899	142	5	a.	a.	PROPN
biomedich-899	142	6	,	,	PUNCT
biomedich-899	142	7	el	el	PROPN
biomedich-899	142	8	-	-	PUNCT
biomedich-899	142	9	sonbati	sonbati	PROPN
biomedich-899	142	10	,	,	PUNCT
biomedich-899	142	11	a.	a.	PROPN
biomedich-899	142	12	z.	z.	PROPN
biomedich-899	142	13	,	,	PUNCT
biomedich-899	142	14	al	al	PROPN
biomedich-899	142	15	-	-	PUNCT
biomedich-899	142	16	halawany	halawany	PROPN
biomedich-899	142	17	,	,	PUNCT
biomedich-899	142	18	m.	m.	NOUN
biomedich-899	142	19	m.	m.	NOUN
biomedich-899	142	20	,	,	PUNCT
biomedich-899	142	21	&	&	CCONJ
biomedich-899	142	22	bader	bader	PROPN
biomedich-899	142	23	,	,	PUNCT
biomedich-899	142	24	d.	d.	PROPN
biomedich-899	142	25	m.	m.	PROPN
biomedich-899	142	26	d.	d.	PROPN
biomedich-899	142	27	(	(	PUNCT
biomedich-899	142	28	2012	2012	NUM
biomedich-899	142	29	)	)	PUNCT
biomedich-899	142	30	.	.	PUNCT
biomedich-899	143	1	thermal	thermal	ADJ
biomedich-899	143	2	stability	stability	NOUN
biomedich-899	143	3	and	and	CCONJ
biomedich-899	143	4	degradation	degradation	NOUN
biomedich-899	143	5	of	of	ADP
biomedich-899	143	6	chitosan	chitosan	NOUN
biomedich-899	143	7	modified	modify	VERB
biomedich-899	143	8	by	by	ADP
biomedich-899	143	9	cinnamic	cinnamic	ADJ
biomedich-899	143	10	acid	acid	NOUN
biomedich-899	143	11	.	.	PUNCT
biomedich-899	144	1	open	open	ADJ
biomedich-899	144	2	journal	journal	NOUN
biomedich-899	144	3	of	of	ADP
biomedich-899	144	4	polymer	polymer	NOUN
biomedich-899	144	5	chemistry	chemistry	NOUN
biomedich-899	144	6	,	,	PUNCT
biomedich-899	144	7	02(01	02(01	NUM
biomedich-899	144	8	)	)	PUNCT
biomedich-899	144	9	,	,	PUNCT
biomedich-899	144	10	14–20	14–20	NUM
biomedich-899	144	11	.	.	PUNCT
biomedich-899	145	1	https://doi.org/10.4236/ojpchem.2012.21003	https://doi.org/10.4236/ojpchem.2012.21003	PROPN
biomedich-899	145	2	dimassi	dimassi	PROPN
biomedich-899	145	3	,	,	PUNCT
biomedich-899	145	4	s.	s.	PROPN
biomedich-899	145	5	,	,	PUNCT
biomedich-899	145	6	tabary	tabary	NOUN
biomedich-899	145	7	,	,	PUNCT
biomedich-899	145	8	n.	n.	NOUN
biomedich-899	145	9	,	,	PUNCT
biomedich-899	145	10	chai	chai	NOUN
biomedich-899	145	11	,	,	PUNCT
biomedich-899	145	12	f.	f.	PROPN
biomedich-899	145	13	,	,	PUNCT
biomedich-899	145	14	blanchemain	blanchemain	NOUN
biomedich-899	145	15	,	,	PUNCT
biomedich-899	145	16	n.	n.	NOUN
biomedich-899	145	17	,	,	PUNCT
biomedich-899	145	18	&	&	CCONJ
biomedich-899	145	19	martel	martel	PROPN
biomedich-899	145	20	,	,	PUNCT
biomedich-899	145	21	b.	b.	PROPN
biomedich-899	145	22	(	(	PUNCT
biomedich-899	145	23	2018	2018	NUM
biomedich-899	145	24	)	)	PUNCT
biomedich-899	145	25	.	.	PUNCT
biomedich-899	146	1	sulfonated	sulfonate	VERB
biomedich-899	146	2	and	and	CCONJ
biomedich-899	146	3	sulfated	sulfate	VERB
biomedich-899	146	4	chitosan	chitosan	NOUN
biomedich-899	146	5	derivatives	derivative	NOUN
biomedich-899	146	6	for	for	ADP
biomedich-899	146	7	biomedical	biomedical	ADJ
biomedich-899	146	8	applications	application	NOUN
biomedich-899	146	9	:	:	PUNCT
biomedich-899	146	10	a	a	DET
biomedich-899	146	11	review	review	NOUN
biomedich-899	146	12	.	.	PUNCT
biomedich-899	147	1	carbohydrate	carbohydrate	NOUN
biomedich-899	147	2	polymers	polymer	NOUN
biomedich-899	147	3	,	,	PUNCT
biomedich-899	147	4	202	202	NUM
biomedich-899	147	5	,	,	PUNCT
biomedich-899	147	6	382–396	382–396	NUM
biomedich-899	147	7	.	.	PUNCT
biomedich-899	148	1	https://doi.org/10.1016/j.carbpol.2018.09.011	https://doi.org/10.1016/j.carbpol.2018.09.011	NUM
biomedich-899	148	2	gao	gao	PROPN
biomedich-899	148	3	,	,	PUNCT
biomedich-899	148	4	y.	y.	PROPN
biomedich-899	148	5	,	,	PUNCT
biomedich-899	148	6	wang	wang	PROPN
biomedich-899	148	7	,	,	PUNCT
biomedich-899	148	8	l.	l.	PROPN
biomedich-899	148	9	,	,	PUNCT
biomedich-899	148	10	zhang	zhang	PROPN
biomedich-899	148	11	,	,	PUNCT
biomedich-899	148	12	x.	x.	PROPN
biomedich-899	148	13	,	,	PUNCT
biomedich-899	148	14	zhou	zhou	PROPN
biomedich-899	148	15	,	,	PUNCT
biomedich-899	148	16	z.	z.	PROPN
biomedich-899	148	17	,	,	PUNCT
biomedich-899	148	18	shen	shen	PROPN
biomedich-899	148	19	,	,	PUNCT
biomedich-899	148	20	x.	x.	PROPN
biomedich-899	148	21	,	,	PUNCT
biomedich-899	148	22	hu	hu	PROPN
biomedich-899	148	23	,	,	PUNCT
biomedich-899	148	24	h.	h.	PROPN
biomedich-899	148	25	,	,	PUNCT
biomedich-899	148	26	sun	sun	PROPN
biomedich-899	148	27	,	,	PUNCT
biomedich-899	148	28	r.	r.	PROPN
biomedich-899	148	29	,	,	PUNCT
biomedich-899	148	30	&	&	CCONJ
biomedich-899	148	31	tang	tang	PROPN
biomedich-899	148	32	,	,	PUNCT
biomedich-899	148	33	j.	j.	PROPN
biomedich-899	148	34	(	(	PUNCT
biomedich-899	148	35	2023	2023	NUM
biomedich-899	148	36	)	)	PUNCT
biomedich-899	148	37	.	.	PUNCT
biomedich-899	149	1	advances	advance	NOUN
biomedich-899	149	2	in	in	ADP
biomedich-899	149	3	self	self	NOUN
biomedich-899	149	4	-	-	PUNCT
biomedich-899	149	5	assembled	assemble	VERB
biomedich-899	149	6	peptides	peptide	NOUN
biomedich-899	149	7	as	as	ADP
biomedich-899	149	8	drug	drug	NOUN
biomedich-899	149	9	carriers	carrier	NOUN
biomedich-899	149	10	.	.	PUNCT
biomedich-899	150	1	pharmaceutics	pharmaceutic	NOUN
biomedich-899	150	2	,	,	PUNCT
biomedich-899	150	3	15(2	15(2	NUM
biomedich-899	150	4	)	)	PUNCT
biomedich-899	150	5	,	,	PUNCT
biomedich-899	150	6	482	482	NUM
biomedich-899	150	7	.	.	PUNCT
biomedich-899	150	8	https://doi.org/10.3390/pharmaceutics15020482	https://doi.org/10.3390/pharmaceutics15020482	PROPN
biomedich-899	150	9	jaidee	jaidee	PROPN
biomedich-899	150	10	,	,	PUNCT
biomedich-899	150	11	a.	a.	NOUN
biomedich-899	150	12	,	,	PUNCT
biomedich-899	150	13	rachtanapun	rachtanapun	NOUN
biomedich-899	150	14	,	,	PUNCT
biomedich-899	150	15	p.	p.	NOUN
biomedich-899	150	16	,	,	PUNCT
biomedich-899	150	17	&	&	CCONJ
biomedich-899	150	18	luangkamin	luangkamin	PROPN
biomedich-899	150	19	,	,	PUNCT
biomedich-899	150	20	s.	s.	PROPN
biomedich-899	150	21	(	(	PUNCT
biomedich-899	150	22	2012	2012	NUM
biomedich-899	150	23	)	)	PUNCT
biomedich-899	150	24	.	.	PUNCT
biomedich-899	151	1	&	&	CCONJ
biomedich-899	151	2	lt;sup>1</sup>h	lt;sup>1</sup>h	PROPN
biomedich-899	151	3	-	-	PUNCT
biomedich-899	151	4	nmr	nmr	NOUN
biomedich-899	151	5	analysis	analysis	NOUN
biomedich-899	151	6	of	of	ADP
biomedich-899	151	7	degree	degree	NOUN
biomedich-899	151	8	of	of	ADP
biomedich-899	151	9	substitution	substitution	NOUN
biomedich-899	151	10	in	in	ADP
biomedich-899	151	11	n	n	CCONJ
biomedich-899	151	12	,	,	PUNCT
biomedich-899	151	13	o	o	ADJ
biomedich-899	151	14	-	-	NOUN
biomedich-899	151	15	carboxymethyl	carboxymethyl	ADJ
biomedich-899	151	16	chitosans	chitosan	NOUN
biomedich-899	151	17	from	from	ADP
biomedich-899	151	18	various	various	ADJ
biomedich-899	151	19	chitosan	chitosan	NOUN
biomedich-899	151	20	sources	source	NOUN
biomedich-899	151	21	and	and	CCONJ
biomedich-899	151	22	types	type	NOUN
biomedich-899	151	23	.	.	PUNCT
biomedich-899	152	1	advanced	advanced	ADJ
biomedich-899	152	2	materials	material	NOUN
biomedich-899	152	3	research	research	NOUN
biomedich-899	152	4	,	,	PUNCT
biomedich-899	152	5	506	506	NUM
biomedich-899	152	6	,	,	PUNCT
biomedich-899	152	7	158–161	158–161	NUM
biomedich-899	152	8	.	.	PUNCT
biomedich-899	153	1	https://doi.org/10.4028/www.scientific.net/amr.506.158	https://doi.org/10.4028/www.scientific.net/amr.506.158	NOUN
biomedich-899	153	2	lazaridou	lazaridou	NOUN
biomedich-899	153	3	,	,	PUNCT
biomedich-899	153	4	m.	m.	NOUN
biomedich-899	153	5	,	,	PUNCT
biomedich-899	153	6	moroni	moroni	PROPN
biomedich-899	153	7	,	,	PUNCT
biomedich-899	153	8	s.	s.	PROPN
biomedich-899	153	9	,	,	PUNCT
biomedich-899	153	10	klonos	klonos	PROPN
biomedich-899	153	11	,	,	PUNCT
biomedich-899	153	12	p.	p.	NOUN
biomedich-899	153	13	,	,	PUNCT
biomedich-899	153	14	kyritsis	kyritsis	PROPN
biomedich-899	153	15	,	,	PUNCT
biomedich-899	153	16	a.	a.	NOUN
biomedich-899	153	17	,	,	PUNCT
biomedich-899	153	18	bikiaris	bikiaris	PROPN
biomedich-899	153	19	,	,	PUNCT
biomedich-899	153	20	d.	d.	PROPN
biomedich-899	153	21	n.	n.	PROPN
biomedich-899	153	22	,	,	PUNCT
biomedich-899	153	23	&	&	CCONJ
biomedich-899	153	24	lamprou	lamprou	PROPN
biomedich-899	153	25	,	,	PUNCT
biomedich-899	153	26	d.	d.	PROPN
biomedich-899	153	27	a.	a.	PROPN
biomedich-899	153	28	(	(	PUNCT
biomedich-899	153	29	2025	2025	NUM
biomedich-899	153	30	)	)	PUNCT
biomedich-899	153	31	.	.	PUNCT
biomedich-899	154	1	3d	3d	NUM
biomedich-899	154	2	-	-	PUNCT
biomedich-899	154	3	printed	print	VERB
biomedich-899	154	4	hydrogels	hydrogel	NOUN
biomedich-899	154	5	based	base	VERB
biomedich-899	154	6	on	on	ADP
biomedich-899	154	7	amphiphilic	amphiphilic	ADJ
biomedich-899	154	8	chitosan	chitosan	NOUN
biomedich-899	154	9	derivative	derivative	NOUN
biomedich-899	154	10	loaded	load	VERB
biomedich-899	154	11	with	with	ADP
biomedich-899	154	12	levofloxacin	levofloxacin	NOUN
biomedich-899	154	13	for	for	ADP
biomedich-899	154	14	wound	wound	ADJ
biomedich-899	154	15	healing	healing	NOUN
biomedich-899	154	16	applications	application	NOUN
biomedich-899	154	17	.	.	PUNCT
biomedich-899	155	1	international	international	ADJ
biomedich-899	155	2	journal	journal	NOUN
biomedich-899	155	3	of	of	ADP
biomedich-899	155	4	polymeric	polymeric	ADJ
biomedich-899	155	5	materials	material	NOUN
biomedich-899	155	6	and	and	CCONJ
biomedich-899	155	7	polymeric	polymeric	ADJ
biomedich-899	155	8	biomaterials	biomaterial	NOUN
biomedich-899	155	9	,	,	PUNCT
biomedich-899	155	10	74(2	74(2	NUM
biomedich-899	155	11	)	)	PUNCT
biomedich-899	155	12	,	,	PUNCT
biomedich-899	155	13	67	67	NUM
biomedich-899	155	14	–	–	SYM
biomedich-899	155	15	84	84	NUM
biomedich-899	155	16	.	.	PUNCT
biomedich-899	156	1	https://doi.org/10.1080/00914037.2024.2314610	https://doi.org/10.1080/00914037.2024.2314610	PROPN
biomedich-899	156	2	pol	pol	PROPN
biomedich-899	156	3	,	,	PUNCT
biomedich-899	156	4	t.	t.	PROPN
biomedich-899	156	5	,	,	PUNCT
biomedich-899	156	6	chonkaew	chonkaew	NOUN
biomedich-899	156	7	,	,	PUNCT
biomedich-899	156	8	w.	w.	PROPN
biomedich-899	156	9	,	,	PUNCT
biomedich-899	156	10	hocharoen	hocharoen	PROPN
biomedich-899	156	11	,	,	PUNCT
biomedich-899	156	12	l.	l.	PROPN
biomedich-899	156	13	,	,	PUNCT
biomedich-899	156	14	niamnont	niamnont	NOUN
biomedich-899	156	15	,	,	PUNCT
biomedich-899	156	16	n.	n.	NOUN
biomedich-899	156	17	,	,	PUNCT
biomedich-899	156	18	butkhot	butkhot	PROPN
biomedich-899	156	19	,	,	PUNCT
biomedich-899	156	20	n.	n.	NOUN
biomedich-899	156	21	,	,	PUNCT
biomedich-899	156	22	roshorm	roshorm	NOUN
biomedich-899	156	23	,	,	PUNCT
biomedich-899	156	24	y.	y.	PROPN
biomedich-899	156	25	m.	m.	PROPN
biomedich-899	156	26	,	,	PUNCT
biomedich-899	156	27	kiatkamjornwong	kiatkamjornwong	PROPN
biomedich-899	156	28	,	,	PUNCT
biomedich-899	156	29	s.	s.	PROPN
biomedich-899	156	30	,	,	PUNCT
biomedich-899	156	31	hoven	hoven	PROPN
biomedich-899	156	32	,	,	PUNCT
biomedich-899	156	33	v.	v.	PROPN
biomedich-899	156	34	p.	p.	PROPN
biomedich-899	156	35	,	,	PUNCT
biomedich-899	156	36	&	&	CCONJ
biomedich-899	156	37	pratumyot	pratumyot	PROPN
biomedich-899	156	38	,	,	PUNCT
biomedich-899	156	39	k.	k.	PROPN
biomedich-899	156	40	(	(	PUNCT
biomedich-899	156	41	2022	2022	NUM
biomedich-899	156	42	)	)	PUNCT
biomedich-899	156	43	.	.	PUNCT
biomedich-899	157	1	amphiphilic	amphiphilic	ADJ
biomedich-899	157	2	chitosan	chitosan	NOUN
biomedich-899	157	3	bearing	bear	VERB
biomedich-899	157	4	double	double	ADJ
biomedich-899	157	5	palmitoyl	palmitoyl	NOUN
biomedich-899	157	6	chains	chain	NOUN
biomedich-899	157	7	and	and	CCONJ
biomedich-899	157	8	quaternary	quaternary	ADJ
biomedich-899	157	9	ammonium	ammonium	NOUN
biomedich-899	157	10	moieties	moiety	NOUN
biomedich-899	157	11	as	as	ADP
biomedich-899	157	12	a	a	DET
biomedich-899	157	13	nanocarrier	nanocarrier	NOUN
biomedich-899	157	14	for	for	ADP
biomedich-899	157	15	plasmid	plasmid	ADJ
biomedich-899	157	16	dna	dna	NOUN
biomedich-899	157	17	.	.	PUNCT
biomedich-899	158	1	acs	acs	PROPN
biomedich-899	158	2	omega	omega	NOUN
biomedich-899	158	3	,	,	PUNCT
biomedich-899	158	4	7(12	7(12	NUM
biomedich-899	158	5	)	)	PUNCT
biomedich-899	158	6	,	,	PUNCT
biomedich-899	158	7	10056	10056	NUM
biomedich-899	158	8	–	–	PUNCT
biomedich-899	158	9	10068	10068	NUM
biomedich-899	158	10	.	.	PUNCT
biomedich-899	159	1	https://doi.org/10.1021/acsomega.1c06101	https://doi.org/10.1021/acsomega.1c06101	PROPN
biomedich-899	159	2	sharma	sharma	PROPN
biomedich-899	159	3	,	,	PUNCT
biomedich-899	159	4	d.	d.	PROPN
biomedich-899	159	5	,	,	PUNCT
biomedich-899	159	6	&	&	CCONJ
biomedich-899	159	7	singh	singh	PROPN
biomedich-899	159	8	,	,	PUNCT
biomedich-899	159	9	j.	j.	PROPN
biomedich-899	159	10	(	(	PUNCT
biomedich-899	159	11	2017	2017	NUM
biomedich-899	159	12	)	)	PUNCT
biomedich-899	159	13	.	.	PUNCT
biomedich-899	160	1	synthesis	synthesis	NOUN
biomedich-899	160	2	and	and	CCONJ
biomedich-899	160	3	characterization	characterization	NOUN
biomedich-899	160	4	of	of	ADP
biomedich-899	160	5	fatty	fatty	NOUN
biomedich-899	160	6	acid	acid	NOUN
biomedich-899	160	7	grafted	graft	VERB
biomedich-899	160	8	chitosan	chitosan	NOUN
biomedich-899	160	9	polymer	polymer	NOUN
biomedich-899	160	10	and	and	CCONJ
biomedich-899	160	11	their	their	PRON
biomedich-899	160	12	nanomicelles	nanomicelle	NOUN
biomedich-899	160	13	for	for	ADP
biomedich-899	160	14	nonviral	nonviral	ADJ
biomedich-899	160	15	gene	gene	NOUN
biomedich-899	160	16	delivery	delivery	NOUN
biomedich-899	160	17	applications	application	NOUN
biomedich-899	160	18	hhs	hhs	VERB
biomedich-899	160	19	public	public	ADJ
biomedich-899	160	20	access	access	NOUN
biomedich-899	160	21	.	.	PUNCT
biomedich-899	161	1	bioconjug	bioconjug	NOUN
biomedich-899	161	2	chem	chem	NOUN
biomedich-899	161	3	,	,	PUNCT
biomedich-899	161	4	28(11	28(11	NUM
biomedich-899	161	5	)	)	PUNCT
biomedich-899	161	6	,	,	PUNCT
biomedich-899	161	7	2772–2783	2772–2783	NUM
biomedich-899	161	8	.	.	PUNCT
biomedich-899	162	1	https://doi.org/10.1021/acs.bioconj-chem.7b00505	https://doi.org/10.1021/acs.bioconj-chem.7b00505	PROPN
biomedich-899	162	2	suendo	suendo	PROPN
biomedich-899	162	3	,	,	PUNCT
biomedich-899	162	4	v.	v.	PROPN
biomedich-899	162	5	,	,	PUNCT
biomedich-899	162	6	ahmad	ahmad	PROPN
biomedich-899	162	7	,	,	PUNCT
biomedich-899	162	8	l.	l.	PROPN
biomedich-899	162	9	o.	o.	PROPN
biomedich-899	162	10	,	,	PUNCT
biomedich-899	162	11	&	&	CCONJ
biomedich-899	162	12	valiyaveetiil	valiyaveetiil	PROPN
biomedich-899	162	13	,	,	PUNCT
biomedich-899	162	14	s.	s.	PROPN
biomedich-899	162	15	(	(	PUNCT
biomedich-899	162	16	2010	2010	NUM
biomedich-899	162	17	)	)	PUNCT
biomedich-899	162	18	.	.	PUNCT
biomedich-899	163	1	deasetilasi	deasetilasi	NOUN
biomedich-899	163	2	kitin	kitin	PROPN
biomedich-899	163	3	secara	secara	PROPN
biomedich-899	163	4	bertahap	bertahap	PROPN
biomedich-899	163	5	dan	dan	PROPN
biomedich-899	163	6	pengaruhnya	pengaruhnya	PROPN
biomedich-899	163	7	terhadap	terhadap	PROPN
biomedich-899	163	8	derajat	derajat	PROPN
biomedich-899	163	9	deasetilasi	deasetilasi	NOUN
biomedich-899	163	10	serta	serta	PROPN
biomedich-899	163	11	massa	massa	PROPN
biomedich-899	163	12	molekul	molekul	PROPN
biomedich-899	163	13	kitosan	kitosan	PROPN
biomedich-899	163	14	.	.	PUNCT
biomedich-899	164	1	jurnal	jurnal	PROPN
biomedich-899	164	2	kimia	kimia	PROPN
biomedich-899	164	3	indonesia	indonesia	PROPN
biomedich-899	164	4	,	,	PUNCT
biomedich-899	164	5	5(1	5(1	NUM
biomedich-899	164	6	)	)	PUNCT
biomedich-899	164	7	,	,	PUNCT
biomedich-899	164	8	17–21	17–21	NUM
biomedich-899	164	9	.	.	PUNCT
biomedich-899	165	1	zvezdova	zvezdova	PROPN
biomedich-899	165	2	,	,	PUNCT
biomedich-899	165	3	d.	d.	PROPN
biomedich-899	165	4	(	(	PUNCT
biomedich-899	165	5	2010	2010	NUM
biomedich-899	165	6	)	)	PUNCT
biomedich-899	165	7	.	.	PUNCT
biomedich-899	166	1	synthesis	synthesis	NOUN
biomedich-899	166	2	and	and	CCONJ
biomedich-899	166	3	characterization	characterization	NOUN
biomedich-899	166	4	of	of	ADP
biomedich-899	166	5	chitosan	chitosan	NOUN
biomedich-899	166	6	from	from	ADP
biomedich-899	166	7	marine	marine	ADJ
biomedich-899	166	8	sources	source	NOUN
biomedich-899	166	9	in	in	ADP
biomedich-899	166	10	black	black	ADJ
biomedich-899	166	11	sea	sea	PROPN
biomedich-899	166	12	.	.	PUNCT
biomedich-899	167	1	scientific	scientific	ADJ
biomedich-899	167	2	works	work	NOUN
biomedich-899	167	3	of	of	ADP
biomedich-899	167	4	the	the	DET
biomedich-899	167	5	rousse	rousse	PROPN
biomedich-899	167	6	university	university	PROPN
biomedich-899	167	7	by	by	ADP
biomedich-899	167	8	bulgaria	bulgaria	PROPN
biomedich-899	167	9	,	,	PUNCT
biomedich-899	167	10	49	49	NUM
biomedich-899	167	11	,	,	PUNCT
biomedich-899	167	12	65–69	65–69	NUM
biomedich-899	167	13	.	.	PUNCT
biomedich-899	168	1	this	this	DET
biomedich-899	168	2	page	page	NOUN
biomedich-899	168	3	intentionally	intentionally	ADV
biomedich-899	168	4	left	leave	VERB
biomedich-899	168	5	blank	blank	ADV