id	sid	tid	token	lemma	pos
biomedich-939	1	1	biology	biology	NOUN
biomedich-939	1	2	,	,	PUNCT
biomedich-939	1	3	medicine	medicine	NOUN
biomedich-939	1	4	,	,	PUNCT
biomedich-939	1	5	&	&	CCONJ
biomedich-939	1	6	natural	natural	ADJ
biomedich-939	1	7	product	product	NOUN
biomedich-939	1	8	chemistry	chemistry	NOUN
biomedich-939	1	9	issn	issn	VERB
biomedich-939	1	10	2089	2089	NUM
biomedich-939	1	11	-	-	SYM
biomedich-939	1	12	6514	6514	NUM
biomedich-939	1	13	(	(	PUNCT
biomedich-939	1	14	paper	paper	NOUN
biomedich-939	1	15	)	)	PUNCT
biomedich-939	1	16	volume	volume	NOUN
biomedich-939	1	17	14	14	NUM
biomedich-939	1	18	,	,	PUNCT
biomedich-939	1	19	number	number	NOUN
biomedich-939	1	20	2	2	NUM
biomedich-939	1	21	,	,	PUNCT
biomedich-939	1	22	october	october	PROPN
biomedich-939	1	23	2025	2025	NUM
biomedich-939	1	24	|	|	ADV
biomedich-939	1	25	pages	page	NOUN
biomedich-939	1	26	:	:	PUNCT
biomedich-939	1	27	843	843	NUM
biomedich-939	1	28	-	-	SYM
biomedich-939	1	29	856	856	NUM
biomedich-939	1	30	|	|	ADV
biomedich-939	1	31	doi	doi	NOUN
biomedich-939	1	32	:	:	PUNCT
biomedich-939	1	33	10.14421	10.14421	NUM
biomedich-939	1	34	/	/	SYM
biomedich-939	1	35	biomedich.2025.142.843	biomedich.2025.142.843	NOUN
biomedich-939	1	36	-	-	PUNCT
biomedich-939	1	37	856	856	NUM
biomedich-939	1	38	issn	issn	PROPN
biomedich-939	1	39	2540	2540	NUM
biomedich-939	1	40	-	-	SYM
biomedich-939	1	41	9328	9328	NUM
biomedich-939	1	42	(	(	PUNCT
biomedich-939	1	43	online	online	ADJ
biomedich-939	1	44	)	)	PUNCT
biomedich-939	1	45	dft	dft	PROPN
biomedich-939	1	46	study	study	NOUN
biomedich-939	1	47	and	and	CCONJ
biomedich-939	1	48	admet	admet	PROPN
biomedich-939	1	49	investigation	investigation	NOUN
biomedich-939	1	50	of	of	ADP
biomedich-939	1	51	bioactive	bioactive	ADJ
biomedich-939	1	52	2	2	NUM
biomedich-939	1	53	-	-	PUNCT
biomedich-939	1	54	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	1	55	oluwafemi	oluwafemi	NOUN
biomedich-939	1	56	s.	s.	PROPN
biomedich-939	1	57	aina1,2	aina1,2	PROPN
biomedich-939	1	58	*	*	PROPN
biomedich-939	1	59	,	,	PUNCT
biomedich-939	1	60	mujeeb	mujeeb	NOUN
biomedich-939	1	61	o.	o.	PROPN
biomedich-939	1	62	rofiu1	rofiu1	PROPN
biomedich-939	1	63	,	,	PUNCT
biomedich-939	1	64	luqman	luqman	PROPN
biomedich-939	1	65	a.	a.	PROPN
biomedich-939	1	66	adams1	adams1	PROPN
biomedich-939	1	67	,	,	PUNCT
biomedich-939	1	68	oluwole	oluwole	PROPN
biomedich-939	1	69	b.	b.	PROPN
biomedich-939	1	70	familoni1	familoni1	PROPN
biomedich-939	2	1	1department	1department	NUM
biomedich-939	2	2	of	of	ADP
biomedich-939	2	3	chemistry	chemistry	NOUN
biomedich-939	2	4	,	,	PUNCT
biomedich-939	2	5	university	university	NOUN
biomedich-939	2	6	of	of	ADP
biomedich-939	2	7	lagos	lago	NOUN
biomedich-939	2	8	,	,	PUNCT
biomedich-939	2	9	lagos	lago	NOUN
biomedich-939	2	10	,	,	PUNCT
biomedich-939	2	11	nigeria	nigeria	PROPN
biomedich-939	2	12	.	.	PUNCT
biomedich-939	3	1	2department	2department	NUM
biomedich-939	3	2	of	of	ADP
biomedich-939	3	3	biological	biological	ADJ
biomedich-939	3	4	sciences	science	NOUN
biomedich-939	3	5	,	,	PUNCT
biomedich-939	3	6	trinity	trinity	NOUN
biomedich-939	3	7	university	university	PROPN
biomedich-939	3	8	,	,	PUNCT
biomedich-939	3	9	lagos	lagos	PROPN
biomedich-939	3	10	,	,	PUNCT
biomedich-939	3	11	nigeria	nigeria	PROPN
biomedich-939	3	12	.	.	PUNCT
biomedich-939	4	1	corresponding	correspond	VERB
biomedich-939	4	2	author	author	NOUN
biomedich-939	4	3	*	*	PROPN
biomedich-939	4	4	oluwafemiaina100@gmail.com	oluwafemiaina100@gmail.com	X
biomedich-939	4	5	manuscript	manuscript	NOUN
biomedich-939	4	6	received	receive	VERB
biomedich-939	4	7	:	:	PUNCT
biomedich-939	4	8	26	26	NUM
biomedich-939	4	9	august	august	PROPN
biomedich-939	4	10	,	,	PUNCT
biomedich-939	4	11	2025	2025	NUM
biomedich-939	4	12	.	.	PUNCT
biomedich-939	5	1	revision	revision	NOUN
biomedich-939	5	2	accepted	accept	VERB
biomedich-939	5	3	:	:	PUNCT
biomedich-939	5	4	14	14	NUM
biomedich-939	5	5	october	october	PROPN
biomedich-939	5	6	,	,	PUNCT
biomedich-939	5	7	2025	2025	NUM
biomedich-939	5	8	.	.	PUNCT
biomedich-939	6	1	published	publish	VERB
biomedich-939	6	2	:	:	PUNCT
biomedich-939	6	3	20	20	NUM
biomedich-939	6	4	october	october	PROPN
biomedich-939	6	5	,	,	PUNCT
biomedich-939	6	6	2025	2025	NUM
biomedich-939	6	7	.	.	PUNCT
biomedich-939	7	1	abstract	abstract	ADJ
biomedich-939	7	2	pharmacologically	pharmacologically	ADV
biomedich-939	7	3	active	active	ADJ
biomedich-939	7	4	quinoline	quinoline	NOUN
biomedich-939	7	5	compounds	compound	NOUN
biomedich-939	7	6	show	show	VERB
biomedich-939	7	7	interesting	interesting	ADJ
biomedich-939	7	8	functionalities	functionality	NOUN
biomedich-939	7	9	.	.	PUNCT
biomedich-939	8	1	however	however	ADV
biomedich-939	8	2	,	,	PUNCT
biomedich-939	8	3	there	there	PRON
biomedich-939	8	4	is	be	VERB
biomedich-939	8	5	still	still	ADV
biomedich-939	8	6	a	a	DET
biomedich-939	8	7	dearth	dearth	NOUN
biomedich-939	8	8	of	of	ADP
biomedich-939	8	9	information	information	NOUN
biomedich-939	8	10	on	on	ADP
biomedich-939	8	11	the	the	DET
biomedich-939	8	12	potential	potential	ADJ
biomedich-939	8	13	wide	wide	ADJ
biomedich-939	8	14	applications	application	NOUN
biomedich-939	8	15	of	of	ADP
biomedich-939	8	16	the	the	DET
biomedich-939	8	17	quinoline	quinoline	NOUN
biomedich-939	8	18	scaffolds	scaffold	NOUN
biomedich-939	8	19	especially	especially	ADV
biomedich-939	8	20	when	when	SCONJ
biomedich-939	8	21	the	the	DET
biomedich-939	8	22	substituents	substituent	NOUN
biomedich-939	8	23	on	on	ADP
biomedich-939	8	24	the	the	DET
biomedich-939	8	25	rings	ring	NOUN
biomedich-939	8	26	or	or	CCONJ
biomedich-939	8	27	functionalities	functionality	NOUN
biomedich-939	8	28	are	be	AUX
biomedich-939	8	29	modified	modify	VERB
biomedich-939	8	30	.	.	PUNCT
biomedich-939	9	1	in	in	ADP
biomedich-939	9	2	this	this	DET
biomedich-939	9	3	study	study	NOUN
biomedich-939	9	4	2	2	NUM
biomedich-939	9	5	-	-	PUNCT
biomedich-939	9	6	phenoxyquinoline-3	phenoxyquinoline-3	NOUN
biomedich-939	9	7	-	-	PUNCT
biomedich-939	9	8	carbaldehyde	carbaldehyde	NOUN
biomedich-939	9	9	derivatives	derivative	NOUN
biomedich-939	9	10	were	be	AUX
biomedich-939	9	11	synthesized	synthesize	VERB
biomedich-939	9	12	and	and	CCONJ
biomedich-939	9	13	investigated	investigate	VERB
biomedich-939	9	14	using	use	VERB
biomedich-939	9	15	dft	dft	PROPN
biomedich-939	9	16	to	to	PART
biomedich-939	9	17	determine	determine	VERB
biomedich-939	9	18	the	the	DET
biomedich-939	9	19	molecular	molecular	ADJ
biomedich-939	9	20	parameters	parameter	NOUN
biomedich-939	9	21	,	,	PUNCT
biomedich-939	9	22	electronic	electronic	ADJ
biomedich-939	9	23	and	and	CCONJ
biomedich-939	9	24	chemical	chemical	NOUN
biomedich-939	9	25	reactivity	reactivity	NOUN
biomedich-939	9	26	descriptors	descriptor	NOUN
biomedich-939	9	27	including	include	VERB
biomedich-939	9	28	their	their	PRON
biomedich-939	9	29	possible	possible	ADJ
biomedich-939	9	30	application	application	NOUN
biomedich-939	9	31	as	as	ADP
biomedich-939	9	32	drug	drug	NOUN
biomedich-939	9	33	candidates	candidate	NOUN
biomedich-939	9	34	.	.	PUNCT
biomedich-939	10	1	geometry	geometry	NOUN
biomedich-939	10	2	optimisations	optimisation	NOUN
biomedich-939	10	3	were	be	AUX
biomedich-939	10	4	carried	carry	VERB
biomedich-939	10	5	out	out	ADP
biomedich-939	10	6	using	use	VERB
biomedich-939	10	7	becke	becke	NOUN
biomedich-939	10	8	three	three	NUM
biomedich-939	10	9	-	-	PUNCT
biomedich-939	10	10	parameter	parameter	NOUN
biomedich-939	10	11	hybrid	hybrid	ADJ
biomedich-939	10	12	functional	functional	ADJ
biomedich-939	10	13	combined	combine	VERB
biomedich-939	10	14	with	with	ADP
biomedich-939	10	15	lee	lee	PROPN
biomedich-939	10	16	-	-	PUNCT
biomedich-939	10	17	yang	yang	PROPN
biomedich-939	10	18	-	-	PUNCT
biomedich-939	10	19	parr	parr	NOUN
biomedich-939	10	20	correlation	correlation	NOUN
biomedich-939	10	21	functionals	functional	NOUN
biomedich-939	10	22	and	and	CCONJ
biomedich-939	10	23	augmented	augment	VERB
biomedich-939	10	24	basis	basis	NOUN
biomedich-939	10	25	set	set	VERB
biomedich-939	10	26	with	with	ADP
biomedich-939	10	27	added	add	VERB
biomedich-939	10	28	sets	set	NOUN
biomedich-939	10	29	of	of	ADP
biomedich-939	10	30	diffuse	diffuse	ADJ
biomedich-939	10	31	sand	sand	NOUN
biomedich-939	10	32	p	p	NOUN
biomedich-939	10	33	-	-	PUNCT
biomedich-939	10	34	functions	function	NOUN
biomedich-939	10	35	:	:	PUNCT
biomedich-939	10	36	bl3yp	bl3yp	NUM
biomedich-939	10	37	/6	/6	PROPN
biomedich-939	10	38	-	-	PUNCT
biomedich-939	10	39	311++g(d	311++g(d	PROPN
biomedich-939	10	40	,	,	PUNCT
biomedich-939	10	41	p	p	NOUN
biomedich-939	10	42	)	)	PUNCT
biomedich-939	10	43	.	.	PUNCT
biomedich-939	11	1	drug	drug	NOUN
biomedich-939	11	2	-	-	PUNCT
biomedich-939	11	3	likeness	likeness	NOUN
biomedich-939	11	4	scores	score	NOUN
biomedich-939	11	5	and	and	CCONJ
biomedich-939	11	6	bioactivity	bioactivity	NOUN
biomedich-939	11	7	prediction	prediction	NOUN
biomedich-939	11	8	were	be	AUX
biomedich-939	11	9	carried	carry	VERB
biomedich-939	11	10	out	out	ADP
biomedich-939	11	11	using	use	VERB
biomedich-939	11	12	the	the	DET
biomedich-939	11	13	webserver	webserver	PROPN
biomedich-939	11	14	programs	program	NOUN
biomedich-939	11	15	admet	admet	PROPN
biomedich-939	11	16	sar	sar	PROPN
biomedich-939	11	17	2	2	PROPN
biomedich-939	11	18	.	.	PUNCT
biomedich-939	12	1	our	our	PRON
biomedich-939	12	2	results	result	NOUN
biomedich-939	12	3	showed	show	VERB
biomedich-939	12	4	slightly	slightly	ADV
biomedich-939	12	5	lower	low	ADJ
biomedich-939	12	6	energy	energy	NOUN
biomedich-939	12	7	values	value	NOUN
biomedich-939	12	8	in	in	ADP
biomedich-939	12	9	water	water	NOUN
biomedich-939	12	10	than	than	ADP
biomedich-939	12	11	in	in	ADP
biomedich-939	12	12	ethanol	ethanol	NOUN
biomedich-939	12	13	depicting	depict	VERB
biomedich-939	12	14	high	high	ADJ
biomedich-939	12	15	reactiveness	reactiveness	NOUN
biomedich-939	12	16	of	of	ADP
biomedich-939	12	17	the	the	DET
biomedich-939	12	18	2	2	NUM
biomedich-939	12	19	-	-	PUNCT
biomedich-939	12	20	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	12	21	in	in	ADP
biomedich-939	12	22	water	water	NOUN
biomedich-939	12	23	especially	especially	ADV
biomedich-939	12	24	compounds	compound	VERB
biomedich-939	12	25	with	with	ADP
biomedich-939	12	26	fluoroand	fluoroand	NOUN
biomedich-939	12	27	methoxy	methoxy	NOUN
biomedich-939	12	28	substituted	substitute	VERB
biomedich-939	12	29	having	have	VERB
biomedich-939	12	30	the	the	DET
biomedich-939	12	31	lowest	low	ADJ
biomedich-939	12	32	egap	egap	NOUN
biomedich-939	12	33	of	of	ADP
biomedich-939	12	34	3.79	3.79	NUM
biomedich-939	12	35	ev	ev	NOUN
biomedich-939	12	36	and	and	CCONJ
biomedich-939	12	37	3.381	3.381	NUM
biomedich-939	12	38	ev	ev	NOUN
biomedich-939	12	39	respectively	respectively	ADV
biomedich-939	12	40	.	.	PUNCT
biomedich-939	13	1	the	the	DET
biomedich-939	13	2	methoxy	methoxy	ADJ
biomedich-939	13	3	substitution	substitution	NOUN
biomedich-939	13	4	confers	confer	NOUN
biomedich-939	13	5	higher	high	ADJ
biomedich-939	13	6	susceptibility	susceptibility	NOUN
biomedich-939	13	7	to	to	PART
biomedich-939	13	8	electron	electron	NOUN
biomedich-939	13	9	transfer	transfer	NOUN
biomedich-939	13	10	and	and	CCONJ
biomedich-939	13	11	chemical	chemical	NOUN
biomedich-939	13	12	reactive	reactive	NOUN
biomedich-939	13	13	in	in	ADP
biomedich-939	13	14	aqeous	aqeous	ADJ
biomedich-939	13	15	medium	medium	NOUN
biomedich-939	13	16	.	.	PUNCT
biomedich-939	14	1	the	the	DET
biomedich-939	14	2	ionization	ionization	NOUN
biomedich-939	14	3	potential	potential	ADJ
biomedich-939	14	4	energies	energy	NOUN
biomedich-939	14	5	were	be	AUX
biomedich-939	14	6	lower	low	ADJ
biomedich-939	14	7	in	in	ADP
biomedich-939	14	8	water	water	NOUN
biomedich-939	14	9	and	and	CCONJ
biomedich-939	14	10	ethanol	ethanol	NOUN
biomedich-939	14	11	when	when	SCONJ
biomedich-939	14	12	compared	compare	VERB
biomedich-939	14	13	to	to	ADP
biomedich-939	14	14	the	the	DET
biomedich-939	14	15	other	other	ADJ
biomedich-939	14	16	gas	gas	NOUN
biomedich-939	14	17	states	state	NOUN
biomedich-939	14	18	calculated	calculate	VERB
biomedich-939	14	19	values	value	NOUN
biomedich-939	14	20	.	.	PUNCT
biomedich-939	15	1	the	the	DET
biomedich-939	15	2	mep	mep	PROPN
biomedich-939	15	3	surfaces	surface	NOUN
biomedich-939	15	4	of	of	ADP
biomedich-939	15	5	all	all	DET
biomedich-939	15	6	the	the	DET
biomedich-939	15	7	compounds	compound	NOUN
biomedich-939	15	8	investigated	investigate	VERB
biomedich-939	15	9	reveals	reveal	VERB
biomedich-939	15	10	the	the	DET
biomedich-939	15	11	ether	ether	ADJ
biomedich-939	15	12	oxygen	oxygen	NOUN
biomedich-939	15	13	atoms	atom	NOUN
biomedich-939	15	14	and	and	CCONJ
biomedich-939	15	15	carbonyl	carbonyl	NOUN
biomedich-939	15	16	groups	group	NOUN
biomedich-939	15	17	as	as	ADP
biomedich-939	15	18	necessities	necessity	NOUN
biomedich-939	15	19	for	for	ADP
biomedich-939	15	20	effective	effective	ADJ
biomedich-939	15	21	antioxidant	antioxidant	ADJ
biomedich-939	15	22	properties	property	NOUN
biomedich-939	15	23	.	.	PUNCT
biomedich-939	16	1	it	it	PRON
biomedich-939	16	2	is	be	AUX
biomedich-939	16	3	noteworthy	noteworthy	ADJ
biomedich-939	16	4	that	that	SCONJ
biomedich-939	16	5	five	five	NUM
biomedich-939	16	6	of	of	ADP
biomedich-939	16	7	the	the	DET
biomedich-939	16	8	compounds	compound	NOUN
biomedich-939	16	9	investigated	investigate	VERB
biomedich-939	16	10	have	have	VERB
biomedich-939	16	11	high	high	ADJ
biomedich-939	16	12	activity	activity	NOUN
biomedich-939	16	13	values	value	NOUN
biomedich-939	16	14	above	above	ADP
biomedich-939	16	15	3.0	3.0	NUM
biomedich-939	16	16	octanol	octanol	NOUN
biomedich-939	16	17	–	–	PUNCT
biomedich-939	16	18	water	water	NOUN
biomedich-939	16	19	partition	partition	NOUN
biomedich-939	16	20	coefficient	coefficient	NOUN
biomedich-939	16	21	value	value	NOUN
biomedich-939	16	22	indicating	indicate	VERB
biomedich-939	16	23	an	an	DET
biomedich-939	16	24	excellent	excellent	ADJ
biomedich-939	16	25	inhibitory	inhibitory	ADJ
biomedich-939	16	26	activity	activity	NOUN
biomedich-939	16	27	and	and	CCONJ
biomedich-939	16	28	strong	strong	ADJ
biomedich-939	16	29	chemical	chemical	NOUN
biomedich-939	16	30	reactivity	reactivity	NOUN
biomedich-939	16	31	.	.	PUNCT
biomedich-939	17	1	good	good	ADJ
biomedich-939	17	2	oral	oral	ADJ
biomedich-939	17	3	bioavailability	bioavailability	NOUN
biomedich-939	17	4	was	be	AUX
biomedich-939	17	5	shown	show	VERB
biomedich-939	17	6	by	by	ADP
biomedich-939	17	7	the	the	DET
biomedich-939	17	8	compounds	compound	NOUN
biomedich-939	17	9	depicting	depict	VERB
biomedich-939	17	10	their	their	PRON
biomedich-939	17	11	excellent	excellent	ADJ
biomedich-939	17	12	activity	activity	NOUN
biomedich-939	17	13	as	as	ADP
biomedich-939	17	14	kinase	kinase	NOUN
biomedich-939	17	15	inhibitors	inhibitor	NOUN
biomedich-939	17	16	,	,	PUNCT
biomedich-939	17	17	nuclear	nuclear	ADJ
biomedich-939	17	18	receptor	receptor	NOUN
biomedich-939	17	19	compounds	compound	NOUN
biomedich-939	17	20	and	and	CCONJ
biomedich-939	17	21	enzyme	enzyme	NOUN
biomedich-939	17	22	inhibitors	inhibitor	NOUN
biomedich-939	17	23	.	.	PUNCT
biomedich-939	18	1	it	it	PRON
biomedich-939	18	2	is	be	AUX
biomedich-939	18	3	noteworthy	noteworthy	ADJ
biomedich-939	18	4	that	that	SCONJ
biomedich-939	18	5	cytochromes	cytochrome	VERB
biomedich-939	18	6	cyp2c19	cyp2c19	PROPN
biomedich-939	18	7	,	,	PUNCT
biomedich-939	18	8	cyp2c29	cyp2c29	PROPN
biomedich-939	18	9	,	,	PUNCT
biomedich-939	18	10	cyp2d6	cyp2d6	NOUN
biomedich-939	18	11	and	and	CCONJ
biomedich-939	18	12	cyp3a4	cyp3a4	NOUN
biomedich-939	18	13	are	be	AUX
biomedich-939	18	14	not	not	PART
biomedich-939	18	15	inhibited	inhibit	VERB
biomedich-939	18	16	and	and	CCONJ
biomedich-939	18	17	therefore	therefore	ADV
biomedich-939	18	18	do	do	AUX
biomedich-939	18	19	not	not	PART
biomedich-939	18	20	pose	pose	VERB
biomedich-939	18	21	potential	potential	ADJ
biomedich-939	18	22	adverse	adverse	ADJ
biomedich-939	18	23	drug	drug	NOUN
biomedich-939	18	24	reactions	reaction	NOUN
biomedich-939	18	25	or	or	CCONJ
biomedich-939	18	26	toxicity	toxicity	NOUN
biomedich-939	18	27	.	.	PUNCT
biomedich-939	19	1	interestingly	interestingly	ADV
biomedich-939	19	2	,	,	PUNCT
biomedich-939	19	3	only	only	ADV
biomedich-939	19	4	one	one	NUM
biomedich-939	19	5	compound	compound	NOUN
biomedich-939	19	6	showed	show	VERB
biomedich-939	19	7	one	one	NUM
biomedich-939	19	8	violation	violation	NOUN
biomedich-939	19	9	.	.	PUNCT
biomedich-939	20	1	consequently	consequently	ADV
biomedich-939	20	2	,	,	PUNCT
biomedich-939	20	3	such	such	ADJ
biomedich-939	20	4	scaffolds	scaffold	NOUN
biomedich-939	20	5	are	be	AUX
biomedich-939	20	6	potential	potential	ADJ
biomedich-939	20	7	drug	drug	NOUN
biomedich-939	20	8	candidates	candidate	NOUN
biomedich-939	20	9	.	.	PUNCT
biomedich-939	21	1	keywords	keyword	NOUN
biomedich-939	21	2	:	:	PUNCT
biomedich-939	21	3	2	2	NUM
biomedich-939	21	4	-	-	PUNCT
biomedich-939	21	5	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	21	6	;	;	PUNCT
biomedich-939	21	7	drug	drug	NOUN
biomedich-939	21	8	-	-	PUNCT
biomedich-939	21	9	likeness	likeness	NOUN
biomedich-939	21	10	;	;	PUNCT
biomedich-939	21	11	cytochrome	cytochrome	ADJ
biomedich-939	21	12	substrate	substrate	NOUN
biomedich-939	21	13	;	;	PUNCT
biomedich-939	21	14	structural	structural	ADJ
biomedich-939	21	15	activity	activity	NOUN
biomedich-939	21	16	relationship	relationship	NOUN
biomedich-939	21	17	.	.	PUNCT
biomedich-939	22	1	introduction	introduction	NOUN
biomedich-939	22	2	quinoline	quinoline	NOUN
biomedich-939	22	3	an	an	DET
biomedich-939	22	4	aromatic	aromatic	ADJ
biomedich-939	22	5	organic	organic	ADJ
biomedich-939	22	6	compound	compound	NOUN
biomedich-939	22	7	is	be	AUX
biomedich-939	22	8	prevalent	prevalent	ADJ
biomedich-939	22	9	in	in	ADP
biomedich-939	22	10	various	various	ADJ
biomedich-939	22	11	pharmacologically	pharmacologically	ADV
biomedich-939	22	12	active	active	ADJ
biomedich-939	22	13	synthetic	synthetic	ADJ
biomedich-939	22	14	and	and	CCONJ
biomedich-939	22	15	natural	natural	ADJ
biomedich-939	22	16	compounds	compound	NOUN
biomedich-939	22	17	.	.	PUNCT
biomedich-939	23	1	it	it	PRON
biomedich-939	23	2	is	be	AUX
biomedich-939	23	3	characterized	characterize	VERB
biomedich-939	23	4	by	by	ADP
biomedich-939	23	5	a	a	DET
biomedich-939	23	6	double	double	ADJ
biomedich-939	23	7	-	-	PUNCT
biomedich-939	23	8	ring	ring	NOUN
biomedich-939	23	9	structure	structure	NOUN
biomedich-939	23	10	containing	contain	VERB
biomedich-939	23	11	a	a	DET
biomedich-939	23	12	benzene	benzene	NOUN
biomedich-939	23	13	ring	ring	NOUN
biomedich-939	23	14	fused	fuse	VERB
biomedich-939	23	15	to	to	ADP
biomedich-939	23	16	pyridine	pyridine	NOUN
biomedich-939	23	17	at	at	ADP
biomedich-939	23	18	two	two	NUM
biomedich-939	23	19	adjacent	adjacent	ADJ
biomedich-939	23	20	carbon	carbon	NOUN
biomedich-939	23	21	atoms	atom	NOUN
biomedich-939	23	22	(	(	PUNCT
biomedich-939	23	23	jain	jain	PROPN
biomedich-939	23	24	et	et	PROPN
biomedich-939	23	25	al	al	PROPN
biomedich-939	23	26	.	.	PROPN
biomedich-939	23	27	,	,	PUNCT
biomedich-939	23	28	2016	2016	NUM
biomedich-939	23	29	)	)	PUNCT
biomedich-939	23	30	and	and	CCONJ
biomedich-939	23	31	have	have	AUX
biomedich-939	23	32	been	be	AUX
biomedich-939	23	33	found	find	VERB
biomedich-939	23	34	highly	highly	ADV
biomedich-939	23	35	useful	useful	ADJ
biomedich-939	23	36	as	as	ADP
biomedich-939	23	37	antimalarial	antimalarial	ADJ
biomedich-939	23	38	,	,	PUNCT
biomedich-939	23	39	anticancer	anticancer	NOUN
biomedich-939	23	40	,	,	PUNCT
biomedich-939	23	41	antiinflammatory	antiinflammatory	NOUN
biomedich-939	23	42	agents	agent	NOUN
biomedich-939	23	43	,	,	PUNCT
biomedich-939	23	44	etc	etc	X
biomedich-939	23	45	.	.	X
biomedich-939	24	1	(	(	PUNCT
biomedich-939	24	2	dib	dib	NOUN
biomedich-939	24	3	et	et	NOUN
biomedich-939	24	4	al	al	PROPN
biomedich-939	24	5	.	.	PROPN
biomedich-939	24	6	,	,	PUNCT
biomedich-939	24	7	2021	2021	NUM
biomedich-939	24	8	)	)	PUNCT
biomedich-939	24	9	leading	lead	VERB
biomedich-939	24	10	to	to	ADP
biomedich-939	24	11	its	its	PRON
biomedich-939	24	12	attraction	attraction	NOUN
biomedich-939	24	13	of	of	ADP
biomedich-939	24	14	great	great	ADJ
biomedich-939	24	15	interest	interest	NOUN
biomedich-939	24	16	in	in	ADP
biomedich-939	24	17	the	the	DET
biomedich-939	24	18	scientific	scientific	ADJ
biomedich-939	24	19	community	community	NOUN
biomedich-939	24	20	.	.	PUNCT
biomedich-939	25	1	researchers	researcher	NOUN
biomedich-939	25	2	have	have	AUX
biomedich-939	25	3	synthesized	synthesize	VERB
biomedich-939	25	4	hybrid	hybrid	ADJ
biomedich-939	25	5	quinoline	quinoline	NOUN
biomedich-939	25	6	scaffolds	scaffold	NOUN
biomedich-939	25	7	using	use	VERB
biomedich-939	25	8	different	different	ADJ
biomedich-939	25	9	procedures	procedure	NOUN
biomedich-939	25	10	(	(	PUNCT
biomedich-939	25	11	figure	figure	NOUN
biomedich-939	25	12	1a	1a	NOUN
biomedich-939	25	13	)	)	PUNCT
biomedich-939	25	14	.	.	PUNCT
biomedich-939	26	1	conventional	conventional	ADJ
biomedich-939	26	2	chemotherapy	chemotherapy	NOUN
biomedich-939	26	3	kills	kill	VERB
biomedich-939	26	4	most	most	ADJ
biomedich-939	26	5	tumour	tumour	ADJ
biomedich-939	26	6	cells	cell	NOUN
biomedich-939	26	7	and	and	CCONJ
biomedich-939	26	8	it	it	PRON
biomedich-939	26	9	is	be	AUX
biomedich-939	26	10	believed	believe	VERB
biomedich-939	26	11	that	that	SCONJ
biomedich-939	26	12	cells	cell	NOUN
biomedich-939	26	13	left	leave	VERB
biomedich-939	26	14	behind	behind	ADV
biomedich-939	26	15	might	might	AUX
biomedich-939	26	16	recur	recur	VERB
biomedich-939	26	17	thereby	thereby	ADV
biomedich-939	26	18	becoming	become	VERB
biomedich-939	26	19	stem	stem	NOUN
biomedich-939	26	20	cells	cell	NOUN
biomedich-939	26	21	which	which	PRON
biomedich-939	26	22	are	be	AUX
biomedich-939	26	23	likely	likely	ADJ
biomedich-939	26	24	to	to	PART
biomedich-939	26	25	share	share	VERB
biomedich-939	26	26	similar	similar	ADJ
biomedich-939	26	27	properties	property	NOUN
biomedich-939	26	28	of	of	ADP
biomedich-939	26	29	parent	parent	NOUN
biomedich-939	26	30	cells	cell	NOUN
biomedich-939	26	31	,	,	PUNCT
biomedich-939	26	32	such	such	ADJ
biomedich-939	26	33	as	as	ADP
biomedich-939	26	34	resistance	resistance	NOUN
biomedich-939	26	35	to	to	ADP
biomedich-939	26	36	drugs	drug	NOUN
biomedich-939	26	37	and	and	CCONJ
biomedich-939	26	38	toxicity	toxicity	NOUN
biomedich-939	26	39	via	via	ADP
biomedich-939	26	40	atp	atp	NOUN
biomedich-939	26	41	-	-	PUNCT
biomedich-939	26	42	binding	bind	VERB
biomedich-939	26	43	cassette	cassette	NOUN
biomedich-939	26	44	(	(	PUNCT
biomedich-939	26	45	abc	abc	PROPN
biomedich-939	26	46	)	)	PUNCT
biomedich-939	26	47	transporter	transporter	NOUN
biomedich-939	26	48	expressions	expression	NOUN
biomedich-939	26	49	(	(	PUNCT
biomedich-939	26	50	suzuki	suzuki	X
biomedich-939	26	51	et	et	PROPN
biomedich-939	26	52	al	al	PROPN
biomedich-939	26	53	.	.	PROPN
biomedich-939	26	54	,	,	PUNCT
biomedich-939	26	55	1997	1997	NUM
biomedich-939	26	56	)	)	PUNCT
biomedich-939	26	57	.	.	PUNCT
biomedich-939	27	1	a	a	DET
biomedich-939	27	2	series	series	NOUN
biomedich-939	27	3	of	of	ADP
biomedich-939	27	4	quinoline	quinoline	NOUN
biomedich-939	27	5	derivatives	derivative	NOUN
biomedich-939	27	6	has	have	AUX
biomedich-939	27	7	been	be	AUX
biomedich-939	27	8	reported	report	VERB
biomedich-939	27	9	to	to	PART
biomedich-939	27	10	show	show	VERB
biomedich-939	27	11	mdrreversing	mdrreversing	NOUN
biomedich-939	27	12	activities	activity	NOUN
biomedich-939	27	13	in	in	ADP
biomedich-939	27	14	k562	k562	PROPN
biomedich-939	27	15	cancer	cancer	NOUN
biomedich-939	27	16	cells	cell	NOUN
biomedich-939	27	17	that	that	PRON
biomedich-939	27	18	are	be	AUX
biomedich-939	27	19	resistant	resistant	ADJ
biomedich-939	27	20	to	to	ADP
biomedich-939	27	21	doxorubicin	doxorubicin	PROPN
biomedich-939	27	22	(	(	PUNCT
biomedich-939	27	23	an	an	DET
biomedich-939	27	24	anthracycline	anthracycline	NOUN
biomedich-939	27	25	multi	multi	ADJ
biomedich-939	27	26	-	-	ADJ
biomedich-939	27	27	cancer	cancer	ADJ
biomedich-939	27	28	therapy	therapy	NOUN
biomedich-939	27	29	)	)	PUNCT
biomedich-939	27	30	which	which	PRON
biomedich-939	27	31	has	have	AUX
biomedich-939	27	32	been	be	AUX
biomedich-939	27	33	identified	identify	VERB
biomedich-939	27	34	as	as	ADP
biomedich-939	27	35	a	a	DET
biomedich-939	27	36	novel	novel	NOUN
biomedich-939	27	37	,	,	PUNCT
biomedich-939	27	38	orally	orally	ADV
biomedich-939	27	39	active	active	ADJ
biomedich-939	27	40	,	,	PUNCT
biomedich-939	27	41	quinoline	quinoline	NOUN
biomedich-939	27	42	-	-	PUNCT
biomedich-939	27	43	derivative	derivative	ADJ
biomedich-939	27	44	inhibitor	inhibitor	NOUN
biomedich-939	27	45	of	of	ADP
biomedich-939	27	46	abcb1	abcb1	NOUN
biomedich-939	28	1	⁄	⁄	PROPN
biomedich-939	28	2	p	p	NOUN
biomedich-939	28	3	-	-	PUNCT
biomedich-939	28	4	gp	gp	NOUN
biomedich-939	28	5	(	(	PUNCT
biomedich-939	28	6	kouznetsov	kouznetsov	PROPN
biomedich-939	28	7	et	et	PROPN
biomedich-939	28	8	al	al	PROPN
biomedich-939	28	9	.	.	PROPN
biomedich-939	28	10	,	,	PUNCT
biomedich-939	28	11	2016	2016	NUM
biomedich-939	28	12	)	)	PUNCT
biomedich-939	28	13	.	.	PUNCT
biomedich-939	29	1	drugs	drug	NOUN
biomedich-939	29	2	and	and	CCONJ
biomedich-939	29	3	candidates	candidate	NOUN
biomedich-939	29	4	such	such	ADJ
biomedich-939	29	5	as	as	ADP
biomedich-939	29	6	lenvatinib	lenvatinib	NOUN
biomedich-939	29	7	,	,	PUNCT
biomedich-939	29	8	cabozantinib	cabozantinib	NOUN
biomedich-939	29	9	and	and	CCONJ
biomedich-939	29	10	dofequidar	dofequidar	NOUN
biomedich-939	29	11	are	be	AUX
biomedich-939	29	12	anticancer	anticancer	NOUN
biomedich-939	29	13	drugs	drug	NOUN
biomedich-939	29	14	based	base	VERB
biomedich-939	29	15	on	on	ADP
biomedich-939	29	16	the	the	DET
biomedich-939	29	17	c-4	c-4	NOUN
biomedich-939	29	18	and	and	CCONJ
biomedich-939	29	19	c-5	c-5	NOUN
biomedich-939	29	20	substituted	substitute	VERB
biomedich-939	29	21	aryloxyquinoline	aryloxyquinoline	NOUN
biomedich-939	29	22	and	and	CCONJ
biomedich-939	29	23	alkoxyquinoline	alkoxyquinoline	NOUN
biomedich-939	29	24	derivatives	derivative	NOUN
biomedich-939	29	25	respectively	respectively	ADV
biomedich-939	29	26	have	have	AUX
biomedich-939	29	27	also	also	ADV
biomedich-939	29	28	been	be	AUX
biomedich-939	29	29	found	find	VERB
biomedich-939	29	30	to	to	PART
biomedich-939	29	31	contain	contain	VERB
biomedich-939	29	32	high	high	ADJ
biomedich-939	29	33	efficacies	efficacy	NOUN
biomedich-939	29	34	as	as	SCONJ
biomedich-939	29	35	shown	show	VERB
biomedich-939	29	36	in	in	ADP
biomedich-939	29	37	figure	figure	NOUN
biomedich-939	29	38	1b	1b	NUM
biomedich-939	29	39	(	(	PUNCT
biomedich-939	29	40	suzuki	suzuki	PROPN
biomedich-939	29	41	et	et	PROPN
biomedich-939	29	42	al	al	PROPN
biomedich-939	29	43	.	.	PROPN
biomedich-939	29	44	,	,	PUNCT
biomedich-939	29	45	1997	1997	NUM
biomedich-939	29	46	;	;	PUNCT
biomedich-939	29	47	katayama	katayama	PROPN
biomedich-939	29	48	et	et	PROPN
biomedich-939	29	49	al	al	PROPN
biomedich-939	29	50	.	.	PROPN
biomedich-939	29	51	,	,	PUNCT
biomedich-939	29	52	2009	2009	NUM
biomedich-939	29	53	)	)	PUNCT
biomedich-939	29	54	.	.	PUNCT
biomedich-939	30	1	https://doi.org/10.14421/biomedich.2025.142.843-856	https://doi.org/10.14421/biomedich.2025.142.843-856	X
biomedich-939	30	2	844	844	NUM
biomedich-939	30	3	biology	biology	NOUN
biomedich-939	30	4	,	,	PUNCT
biomedich-939	30	5	medicine	medicine	NOUN
biomedich-939	30	6	,	,	PUNCT
biomedich-939	30	7	&	&	CCONJ
biomedich-939	30	8	natural	natural	ADJ
biomedich-939	30	9	product	product	NOUN
biomedich-939	30	10	chemistry	chemistry	NOUN
biomedich-939	30	11	14	14	NUM
biomedich-939	30	12	(	(	PUNCT
biomedich-939	30	13	2	2	NUM
biomedich-939	30	14	)	)	PUNCT
biomedich-939	30	15	,	,	PUNCT
biomedich-939	30	16	2025	2025	NUM
biomedich-939	30	17	:	:	PUNCT
biomedich-939	30	18	843	843	NUM
biomedich-939	30	19	-	-	SYM
biomedich-939	30	20	856	856	NUM
biomedich-939	30	21	figure	figure	NOUN
biomedich-939	30	22	1a	1a	NOUN
biomedich-939	30	23	.	.	PUNCT
biomedich-939	31	1	some	some	DET
biomedich-939	31	2	applications	application	NOUN
biomedich-939	31	3	of	of	ADP
biomedich-939	31	4	2	2	NUM
biomedich-939	31	5	-	-	PUNCT
biomedich-939	31	6	phenoxyquinoline	phenoxyquinoline	NOUN
biomedich-939	31	7	derivatives	derivative	NOUN
biomedich-939	31	8	.	.	PUNCT
biomedich-939	32	1	figure	figure	VERB
biomedich-939	32	2	1b	1b	NUM
biomedich-939	32	3	.	.	PUNCT
biomedich-939	33	1	anticancer	anticancer	NOUN
biomedich-939	33	2	drugs	drug	NOUN
biomedich-939	33	3	with	with	ADP
biomedich-939	33	4	the	the	DET
biomedich-939	33	5	alkyl	alkyl	PROPN
biomedich-939	33	6	/	/	SYM
biomedich-939	33	7	aryloxyquinoline	aryloxyquinoline	NOUN
biomedich-939	33	8	moiety	moiety	NOUN
biomedich-939	33	9	.	.	PUNCT
biomedich-939	34	1	methodology	methodology	PROPN
biomedich-939	34	2	different	different	ADJ
biomedich-939	34	3	novel	novel	ADJ
biomedich-939	34	4	methods	method	NOUN
biomedich-939	34	5	have	have	AUX
biomedich-939	34	6	resulted	result	VERB
biomedich-939	34	7	to	to	ADP
biomedich-939	34	8	synthesis	synthesis	NOUN
biomedich-939	34	9	of	of	ADP
biomedich-939	34	10	this	this	DET
biomedich-939	34	11	bioactive	bioactive	ADJ
biomedich-939	34	12	moiety	moiety	NOUN
biomedich-939	34	13	for	for	ADP
biomedich-939	34	14	more	more	ADJ
biomedich-939	34	15	than	than	ADP
biomedich-939	34	16	five	five	NUM
biomedich-939	34	17	decades	decade	NOUN
biomedich-939	34	18	and	and	CCONJ
biomedich-939	34	19	these	these	DET
biomedich-939	34	20	methodologies	methodology	NOUN
biomedich-939	34	21	have	have	AUX
biomedich-939	34	22	all	all	PRON
biomedich-939	34	23	been	be	AUX
biomedich-939	34	24	modified	modify	VERB
biomedich-939	34	25	with	with	ADP
biomedich-939	34	26	eco	eco	NOUN
biomedich-939	34	27	-	-	PUNCT
biomedich-939	34	28	friendly	friendly	ADJ
biomedich-939	34	29	transition	transition	NOUN
biomedich-939	34	30	metal	metal	NOUN
biomedich-939	34	31	mediated	mediate	VERB
biomedich-939	34	32	,	,	PUNCT
biomedich-939	34	33	traditional	traditional	ADJ
biomedich-939	34	34	methods	method	NOUN
biomedich-939	34	35	,	,	PUNCT
biomedich-939	34	36	microwave	microwave	NOUN
biomedich-939	34	37	or	or	CCONJ
biomedich-939	34	38	ultrasonic	ultrasonic	ADJ
biomedich-939	34	39	irradiation	irradiation	NOUN
biomedich-939	34	40	,	,	PUNCT
biomedich-939	34	41	oxidation	oxidation	NOUN
biomedich-939	34	42	of	of	ADP
biomedich-939	34	43	the	the	DET
biomedich-939	34	44	corresponding	correspond	VERB
biomedich-939	34	45	alcohols	alcohol	NOUN
biomedich-939	34	46	or	or	CCONJ
biomedich-939	34	47	greener	green	ADJ
biomedich-939	34	48	protocols	protocol	NOUN
biomedich-939	34	49	(	(	PUNCT
biomedich-939	34	50	sharma	sharma	PROPN
biomedich-939	34	51	et	et	PROPN
biomedich-939	34	52	al	al	PROPN
biomedich-939	34	53	.	.	PROPN
biomedich-939	34	54	,	,	PUNCT
biomedich-939	34	55	2018	2018	NUM
biomedich-939	34	56	;	;	PUNCT
biomedich-939	34	57	ramírez	ramírez	NOUN
biomedich-939	34	58	et	et	PROPN
biomedich-939	34	59	al	al	PROPN
biomedich-939	34	60	.	.	PROPN
biomedich-939	34	61	,	,	PUNCT
biomedich-939	34	62	2022	2022	NUM
biomedich-939	34	63	)	)	PUNCT
biomedich-939	34	64	.	.	PUNCT
biomedich-939	35	1	amongst	amongst	ADP
biomedich-939	35	2	the	the	DET
biomedich-939	35	3	contemporary	contemporary	ADJ
biomedich-939	35	4	methodologies	methodology	NOUN
biomedich-939	35	5	are	be	AUX
biomedich-939	35	6	the	the	DET
biomedich-939	35	7	conventional	conventional	ADJ
biomedich-939	35	8	methods	method	NOUN
biomedich-939	35	9	such	such	ADJ
biomedich-939	35	10	as	as	ADP
biomedich-939	35	11	condensation	condensation	NOUN
biomedich-939	35	12	of	of	ADP
biomedich-939	35	13	amines	amine	NOUN
biomedich-939	35	14	and	and	CCONJ
biomedich-939	35	15	carbonyl	carbonyl	NOUN
biomedich-939	35	16	compounds	compound	NOUN
biomedich-939	35	17	with	with	ADP
biomedich-939	35	18	numerous	numerous	ADJ
biomedich-939	35	19	substrate	substrate	NOUN
biomedich-939	35	20	scope	scope	NOUN
biomedich-939	35	21	(	(	PUNCT
biomedich-939	35	22	kouznetsov	kouznetsov	PROPN
biomedich-939	35	23	et	et	PROPN
biomedich-939	35	24	al	al	PROPN
biomedich-939	35	25	.	.	PROPN
biomedich-939	35	26	,	,	PUNCT
biomedich-939	35	27	2005	2005	NUM
biomedich-939	35	28	;	;	PUNCT
biomedich-939	35	29	iwai	iwai	PROPN
biomedich-939	35	30	&	&	CCONJ
biomedich-939	35	31	sawamura	sawamura	PROPN
biomedich-939	35	32	,	,	PUNCT
biomedich-939	35	33	2015	2015	NUM
biomedich-939	35	34	)	)	PUNCT
biomedich-939	35	35	.	.	PUNCT
biomedich-939	36	1	synthesis	synthesis	NOUN
biomedich-939	36	2	of	of	ADP
biomedich-939	36	3	precursors	precursor	NOUN
biomedich-939	36	4	and	and	CCONJ
biomedich-939	36	5	target	target	NOUN
biomedich-939	36	6	compounds	compound	NOUN
biomedich-939	36	7	vilsmeier	vilsmeier	PROPN
biomedich-939	36	8	-	-	PUNCT
biomedich-939	36	9	haack	haack	PROPN
biomedich-939	36	10	reaction	reaction	NOUN
biomedich-939	36	11	of	of	ADP
biomedich-939	36	12	acetanilides	acetanilide	NOUN
biomedich-939	36	13	,	,	PUNCT
biomedich-939	36	14	one	one	NUM
biomedich-939	36	15	of	of	ADP
biomedich-939	36	16	the	the	DET
biomedich-939	36	17	practically	practically	ADV
biomedich-939	36	18	important	important	ADJ
biomedich-939	36	19	routes	route	NOUN
biomedich-939	36	20	to	to	ADP
biomedich-939	36	21	synthesis	synthesis	NOUN
biomedich-939	36	22	of	of	ADP
biomedich-939	36	23	2chloroquinoline-3	2chloroquinoline-3	NUM
biomedich-939	36	24	-	-	PUNCT
biomedich-939	36	25	carbaldehydes	carbaldehyde	NOUN
biomedich-939	36	26	,	,	PUNCT
biomedich-939	36	27	involves	involve	VERB
biomedich-939	36	28	the	the	DET
biomedich-939	36	29	processes	process	NOUN
biomedich-939	36	30	of	of	ADP
biomedich-939	36	31	chlorination	chlorination	NOUN
biomedich-939	36	32	,	,	PUNCT
biomedich-939	36	33	formylation	formylation	NOUN
biomedich-939	36	34	and	and	CCONJ
biomedich-939	36	35	cyclization	cyclization	NOUN
biomedich-939	36	36	of	of	ADP
biomedich-939	36	37	acetanilides	acetanilide	NOUN
biomedich-939	36	38	by	by	ADP
biomedich-939	36	39	the	the	DET
biomedich-939	36	40	action	action	NOUN
biomedich-939	36	41	of	of	ADP
biomedich-939	36	42	the	the	DET
biomedich-939	36	43	vilsmeier	vilsmeier	NOUN
biomedich-939	36	44	́s	́s	PROPN
biomedich-939	36	45	reagent	reagent	NOUN
biomedich-939	36	46	(	(	PUNCT
biomedich-939	36	47	dmf	dmf	PROPN
biomedich-939	36	48	/	/	SYM
biomedich-939	36	49	pocl3	pocl3	PROPN
biomedich-939	36	50	)	)	PUNCT
biomedich-939	36	51	to	to	PART
biomedich-939	36	52	afford	afford	VERB
biomedich-939	36	53	2	2	NUM
biomedich-939	36	54	-	-	PUNCT
biomedich-939	36	55	chloroquinoline-3carbaldehydes	chloroquinoline-3carbaldehyde	NOUN
biomedich-939	36	56	as	as	SCONJ
biomedich-939	36	57	shown	show	VERB
biomedich-939	36	58	in	in	ADP
biomedich-939	36	59	scheme	scheme	NOUN
biomedich-939	36	60	1	1	NUM
biomedich-939	36	61	(	(	PUNCT
biomedich-939	36	62	meth	meth	NOUN
biomedich-939	36	63	-	-	PUNCT
biomedich-939	36	64	cohn	cohn	PROPN
biomedich-939	36	65	et	et	PROPN
biomedich-939	36	66	al	al	PROPN
biomedich-939	36	67	.	.	PROPN
biomedich-939	36	68	,	,	PUNCT
biomedich-939	36	69	1981	1981	NUM
biomedich-939	36	70	)	)	PUNCT
biomedich-939	36	71	.	.	PUNCT
biomedich-939	37	1	the	the	DET
biomedich-939	37	2	adducts	adduct	NOUN
biomedich-939	37	3	obtained	obtain	VERB
biomedich-939	37	4	from	from	ADP
biomedich-939	37	5	vismeier	vismei	ADJ
biomedich-939	37	6	reaction	reaction	NOUN
biomedich-939	37	7	could	could	AUX
biomedich-939	37	8	undergo	undergo	VERB
biomedich-939	37	9	substitution	substitution	NOUN
biomedich-939	37	10	reaction	reaction	NOUN
biomedich-939	37	11	at	at	ADP
biomedich-939	37	12	positions	position	NOUN
biomedich-939	37	13	2	2	NUM
biomedich-939	37	14	and	and	CCONJ
biomedich-939	37	15	3	3	NUM
biomedich-939	37	16	where	where	SCONJ
biomedich-939	37	17	the	the	DET
biomedich-939	37	18	active	active	ADJ
biomedich-939	37	19	chloro	chloro	NOUN
biomedich-939	37	20	and	and	CCONJ
biomedich-939	37	21	the	the	DET
biomedich-939	37	22	aldehyde	aldehyde	NOUN
biomedich-939	37	23	groups	group	NOUN
biomedich-939	37	24	could	could	AUX
biomedich-939	37	25	lead	lead	VERB
biomedich-939	37	26	to	to	ADP
biomedich-939	37	27	numerous	numerous	ADJ
biomedich-939	37	28	functionalization	functionalization	NOUN
biomedich-939	37	29	under	under	ADP
biomedich-939	37	30	appropriate	appropriate	ADJ
biomedich-939	37	31	reagents	reagent	NOUN
biomedich-939	37	32	(	(	PUNCT
biomedich-939	37	33	abdel	abdel	PROPN
biomedich-939	37	34	-	-	PUNCT
biomedich-939	37	35	wahab	wahab	PROPN
biomedich-939	37	36	&	&	CCONJ
biomedich-939	37	37	khidre	khidre	PROPN
biomedich-939	37	38	,	,	PUNCT
biomedich-939	37	39	2013	2013	NUM
biomedich-939	37	40	)	)	PUNCT
biomedich-939	37	41	.	.	PUNCT
biomedich-939	38	1	scheme	scheme	NOUN
biomedich-939	38	2	1	1	NUM
biomedich-939	38	3	.	.	PUNCT
biomedich-939	38	4	synthesis	synthesis	NOUN
biomedich-939	38	5	of	of	ADP
biomedich-939	38	6	2	2	NUM
biomedich-939	38	7	-	-	PUNCT
biomedich-939	38	8	chloroquinoline-3	chloroquinoline-3	NUM
biomedich-939	38	9	-	-	PUNCT
biomedich-939	38	10	carbaldehyde	carbaldehyde	NOUN
biomedich-939	38	11	and	and	CCONJ
biomedich-939	38	12	its	its	PRON
biomedich-939	38	13	phenoxylated	phenoxylated	ADJ
biomedich-939	38	14	adducts	adduct	NOUN
biomedich-939	38	15	as	as	ADP
biomedich-939	38	16	precursors	precursor	NOUN
biomedich-939	38	17	(	(	PUNCT
biomedich-939	38	18	cf	cf	NOUN
biomedich-939	38	19	:	:	PUNCT
biomedich-939	38	20	bakthadoss	bakthadoss	PROPN
biomedich-939	38	21	&	&	CCONJ
biomedich-939	38	22	aina	aina	PROPN
biomedich-939	38	23	et	et	PROPN
biomedich-939	38	24	al	al	PROPN
biomedich-939	38	25	,	,	PUNCT
biomedich-939	38	26	2024	2024	NUM
biomedich-939	38	27	)	)	PUNCT
biomedich-939	38	28	.	.	PUNCT
biomedich-939	39	1	aina	aina	PROPN
biomedich-939	39	2	et	et	PROPN
biomedich-939	39	3	al	al	PROPN
biomedich-939	39	4	.	.	PROPN
biomedich-939	39	5	–	–	PUNCT
biomedich-939	39	6	dft	dft	PROPN
biomedich-939	39	7	study	study	NOUN
biomedich-939	39	8	and	and	CCONJ
biomedich-939	39	9	admet	admet	PROPN
biomedich-939	39	10	investigation	investigation	NOUN
biomedich-939	39	11	of	of	ADP
biomedich-939	39	12	bioactive	bioactive	ADJ
biomedich-939	39	13	2	2	NUM
biomedich-939	39	14	-	-	PUNCT
biomedich-939	39	15	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	39	16	845	845	NUM
biomedich-939	39	17	scheme	scheme	NOUN
biomedich-939	39	18	2	2	NUM
biomedich-939	39	19	.	.	PUNCT
biomedich-939	39	20	synthesis	synthesis	NOUN
biomedich-939	39	21	of	of	ADP
biomedich-939	39	22	acetoxylated	acetoxylated	ADJ
biomedich-939	39	23	and	and	CCONJ
biomedich-939	39	24	benzoylated	benzoylate	VERB
biomedich-939	39	25	2	2	NUM
biomedich-939	39	26	-	-	PUNCT
biomedich-939	39	27	phenoxychloroquinoline-3	phenoxychloroquinoline-3	NUM
biomedich-939	39	28	-	-	PUNCT
biomedich-939	39	29	carbaldehydes	carbaldehyde	NOUN
biomedich-939	39	30	via	via	ADP
biomedich-939	39	31	nitrogen	nitrogen	NOUN
biomedich-939	39	32	-	-	PUNCT
biomedich-939	39	33	directed	direct	VERB
biomedich-939	39	34	palladium	palladium	NOUN
biomedich-939	39	35	-	-	PUNCT
biomedich-939	39	36	catalysed	catalyse	VERB
biomedich-939	39	37	sp2	sp2	NOUN
biomedich-939	39	38	c	c	NOUN
biomedich-939	39	39	-	-	PUNCT
biomedich-939	39	40	h	h	NOUN
biomedich-939	39	41	activation	activation	NOUN
biomedich-939	39	42	strategy	strategy	NOUN
biomedich-939	39	43	(	(	PUNCT
biomedich-939	39	44	cf	cf	NOUN
biomedich-939	39	45	:	:	PUNCT
biomedich-939	39	46	bakthadoss	bakthadoss	PROPN
biomedich-939	39	47	&	&	CCONJ
biomedich-939	39	48	aina	aina	PROPN
biomedich-939	39	49	et	et	PROPN
biomedich-939	39	50	al	al	PROPN
biomedich-939	39	51	,	,	PUNCT
biomedich-939	39	52	2024	2024	NUM
biomedich-939	39	53	)	)	PUNCT
biomedich-939	39	54	.	.	PUNCT
biomedich-939	40	1	interest	interest	NOUN
biomedich-939	40	2	in	in	ADP
biomedich-939	40	3	the	the	DET
biomedich-939	40	4	use	use	NOUN
biomedich-939	40	5	of	of	ADP
biomedich-939	40	6	these	these	DET
biomedich-939	40	7	bioactive	bioactive	ADJ
biomedich-939	40	8	organic	organic	ADJ
biomedich-939	40	9	molecules	molecule	NOUN
biomedich-939	40	10	possessing	possess	VERB
biomedich-939	40	11	high	high	ADJ
biomedich-939	40	12	degree	degree	NOUN
biomedich-939	40	13	of	of	ADP
biomedich-939	40	14	delocalization	delocalization	NOUN
biomedich-939	40	15	has	have	AUX
biomedich-939	40	16	increased	increase	VERB
biomedich-939	40	17	in	in	ADP
biomedich-939	40	18	the	the	DET
biomedich-939	40	19	recent	recent	ADJ
biomedich-939	40	20	time	time	NOUN
biomedich-939	40	21	due	due	ADP
biomedich-939	40	22	to	to	ADP
biomedich-939	40	23	presence	presence	NOUN
biomedich-939	40	24	of	of	ADP
biomedich-939	40	25	weak	weak	ADJ
biomedich-939	40	26	van	van	PROPN
biomedich-939	40	27	der	der	PROPN
biomedich-939	40	28	waal	waal	PROPN
biomedich-939	40	29	’s	’s	PART
biomedich-939	40	30	and	and	CCONJ
biomedich-939	40	31	hydrogen	hydrogen	NOUN
biomedich-939	40	32	bonds	bond	NOUN
biomedich-939	40	33	resulting	result	VERB
biomedich-939	40	34	to	to	ADP
biomedich-939	40	35	better	well	ADJ
biomedich-939	40	36	enzyme	enzyme	NOUN
biomedich-939	40	37	-	-	PUNCT
biomedich-939	40	38	compound	compound	NOUN
biomedich-939	40	39	interactions	interaction	NOUN
biomedich-939	40	40	(	(	PUNCT
biomedich-939	40	41	kumar	kumar	PROPN
biomedich-939	40	42	et	et	PROPN
biomedich-939	40	43	al	al	PROPN
biomedich-939	40	44	.	.	PROPN
biomedich-939	40	45	,	,	PUNCT
biomedich-939	40	46	2017	2017	NUM
biomedich-939	40	47	)	)	PUNCT
biomedich-939	40	48	.	.	PUNCT
biomedich-939	41	1	to	to	ADP
biomedich-939	41	2	this	this	DET
biomedich-939	41	3	end	end	NOUN
biomedich-939	41	4	,	,	PUNCT
biomedich-939	41	5	our	our	PRON
biomedich-939	41	6	study	study	NOUN
biomedich-939	41	7	therefore	therefore	ADV
biomedich-939	41	8	presents	present	VERB
biomedich-939	41	9	density	density	NOUN
biomedich-939	41	10	function	function	NOUN
biomedich-939	41	11	theory	theory	NOUN
biomedich-939	41	12	(	(	PUNCT
biomedich-939	41	13	dft	dft	PROPN
biomedich-939	41	14	)	)	PUNCT
biomedich-939	41	15	with	with	ADP
biomedich-939	41	16	detailed	detailed	ADJ
biomedich-939	41	17	chemical	chemical	NOUN
biomedich-939	41	18	reactivities	reactivity	NOUN
biomedich-939	41	19	of	of	ADP
biomedich-939	41	20	eight	eight	NUM
biomedich-939	41	21	(	(	PUNCT
biomedich-939	41	22	8)	8)	NUM
biomedich-939	41	23	2	2	NUM
biomedich-939	41	24	-	-	PUNCT
biomedich-939	41	25	phenoxyquinoline	phenoxyquinoline	NOUN
biomedich-939	41	26	derivatives	derivative	NOUN
biomedich-939	41	27	shown	show	VERB
biomedich-939	41	28	in	in	ADP
biomedich-939	41	29	figure	figure	NOUN
biomedich-939	41	30	2	2	NUM
biomedich-939	41	31	synthesized	synthesize	VERB
biomedich-939	41	32	using	use	VERB
biomedich-939	41	33	the	the	DET
biomedich-939	41	34	methods	method	NOUN
biomedich-939	41	35	presented	present	VERB
biomedich-939	41	36	in	in	ADP
biomedich-939	41	37	scheme	scheme	NOUN
biomedich-939	41	38	2	2	NUM
biomedich-939	41	39	to	to	PART
biomedich-939	41	40	investigate	investigate	VERB
biomedich-939	41	41	their	their	PRON
biomedich-939	41	42	possible	possible	ADJ
biomedich-939	41	43	application	application	NOUN
biomedich-939	41	44	as	as	ADP
biomedich-939	41	45	drug	drug	NOUN
biomedich-939	41	46	candidates	candidate	NOUN
biomedich-939	41	47	with	with	ADP
biomedich-939	41	48	emphasis	emphasis	NOUN
biomedich-939	41	49	on	on	ADP
biomedich-939	41	50	their	their	PRON
biomedich-939	41	51	toxicity	toxicity	NOUN
biomedich-939	41	52	.	.	PUNCT
biomedich-939	42	1	quantum	quantum	ADJ
biomedich-939	42	2	mechanical	mechanical	ADJ
biomedich-939	42	3	calculations	calculation	NOUN
biomedich-939	42	4	were	be	AUX
biomedich-939	42	5	also	also	ADV
biomedich-939	42	6	performed	perform	VERB
biomedich-939	42	7	to	to	PART
biomedich-939	42	8	examine	examine	VERB
biomedich-939	42	9	their	their	PRON
biomedich-939	42	10	molecular	molecular	ADJ
biomedich-939	42	11	structures	structure	NOUN
biomedich-939	42	12	,	,	PUNCT
biomedich-939	42	13	parameters	parameter	NOUN
biomedich-939	42	14	,	,	PUNCT
biomedich-939	42	15	molecular	molecular	ADJ
biomedich-939	42	16	electronic	electronic	ADJ
biomedich-939	42	17	and	and	CCONJ
biomedich-939	42	18	chemical	chemical	NOUN
biomedich-939	42	19	reactivity	reactivity	NOUN
biomedich-939	42	20	descriptors	descriptor	NOUN
biomedich-939	42	21	.	.	PUNCT
biomedich-939	43	1	computational	computational	ADJ
biomedich-939	43	2	methodology	methodology	NOUN
biomedich-939	43	3	the	the	DET
biomedich-939	43	4	coordinates	coordinate	NOUN
biomedich-939	43	5	of	of	ADP
biomedich-939	43	6	the	the	DET
biomedich-939	43	7	structures	structure	NOUN
biomedich-939	43	8	of	of	ADP
biomedich-939	43	9	synthesised	synthesise	VERB
biomedich-939	43	10	compounds	compound	NOUN
biomedich-939	43	11	were	be	AUX
biomedich-939	43	12	generated	generate	VERB
biomedich-939	43	13	from	from	ADP
biomedich-939	43	14	avogadro	avogadro	PROPN
biomedich-939	43	15	14.0	14.0	NUM
biomedich-939	43	16	while	while	SCONJ
biomedich-939	43	17	molecular	molecular	ADJ
biomedich-939	43	18	optimization	optimization	NOUN
biomedich-939	43	19	calculations	calculation	NOUN
biomedich-939	43	20	were	be	AUX
biomedich-939	43	21	done	do	VERB
biomedich-939	43	22	using	use	VERB
biomedich-939	43	23	the	the	DET
biomedich-939	43	24	orca	orca	NOUN
biomedich-939	43	25	4.2.1	4.2.1	NUM
biomedich-939	43	26	quantum	quantum	ADJ
biomedich-939	43	27	chemical	chemical	NOUN
biomedich-939	43	28	software	software	NOUN
biomedich-939	43	29	.	.	PUNCT
biomedich-939	44	1	(	(	PUNCT
biomedich-939	44	2	neese	neese	PROPN
biomedich-939	44	3	,	,	PUNCT
biomedich-939	44	4	2017	2017	NUM
biomedich-939	44	5	)	)	PUNCT
biomedich-939	44	6	.	.	PUNCT
biomedich-939	45	1	the	the	DET
biomedich-939	45	2	geometry	geometry	NOUN
biomedich-939	45	3	optimisation	optimisation	NOUN
biomedich-939	45	4	was	be	AUX
biomedich-939	45	5	carried	carry	VERB
biomedich-939	45	6	out	out	ADP
biomedich-939	45	7	using	use	VERB
biomedich-939	45	8	the	the	DET
biomedich-939	45	9	becke	becke	NOUN
biomedich-939	45	10	three	three	NUM
biomedich-939	45	11	-	-	PUNCT
biomedich-939	45	12	parameter	parameter	NOUN
biomedich-939	45	13	hybrid	hybrid	ADJ
biomedich-939	45	14	functional	functional	ADJ
biomedich-939	45	15	combined	combine	VERB
biomedich-939	45	16	with	with	ADP
biomedich-939	45	17	leeyang	leeyang	NOUN
biomedich-939	45	18	-	-	PUNCT
biomedich-939	45	19	parr	parr	NOUN
biomedich-939	45	20	correlation	correlation	NOUN
biomedich-939	45	21	functionals	functional	NOUN
biomedich-939	45	22	and	and	CCONJ
biomedich-939	45	23	augmented	augment	VERB
biomedich-939	45	24	basis	basis	NOUN
biomedich-939	45	25	set	set	VERB
biomedich-939	45	26	with	with	ADP
biomedich-939	45	27	added	add	VERB
biomedich-939	45	28	sets	set	NOUN
biomedich-939	45	29	of	of	ADP
biomedich-939	45	30	diffuse	diffuse	ADJ
biomedich-939	45	31	sand	sand	NOUN
biomedich-939	45	32	p	p	NOUN
biomedich-939	45	33	-	-	PUNCT
biomedich-939	45	34	functions	function	NOUN
biomedich-939	45	35	:	:	PUNCT
biomedich-939	45	36	bl3yp	bl3yp	NUM
biomedich-939	45	37	/6	/6	PROPN
biomedich-939	45	38	-	-	PUNCT
biomedich-939	45	39	311++g(d	311++g(d	PROPN
biomedich-939	45	40	,	,	PUNCT
biomedich-939	45	41	p	p	NOUN
biomedich-939	45	42	)	)	PUNCT
biomedich-939	45	43	(	(	PUNCT
biomedich-939	45	44	ennaba	ennaba	NOUN
biomedich-939	45	45	,	,	PUNCT
biomedich-939	45	46	2017	2017	NUM
biomedich-939	45	47	;	;	PUNCT
biomedich-939	45	48	kodikara	kodikara	NOUN
biomedich-939	45	49	et	et	PROPN
biomedich-939	45	50	al	al	PROPN
biomedich-939	45	51	.	.	PROPN
biomedich-939	45	52	,	,	PUNCT
biomedich-939	45	53	2018	2018	NUM
biomedich-939	45	54	;	;	PUNCT
biomedich-939	45	55	al	al	PROPN
biomedich-939	45	56	hasanat	hasanat	PROPN
biomedich-939	45	57	,	,	PUNCT
biomedich-939	45	58	2017	2017	NUM
biomedich-939	45	59	)	)	PUNCT
biomedich-939	45	60	.	.	PUNCT
biomedich-939	46	1	the	the	DET
biomedich-939	46	2	choice	choice	NOUN
biomedich-939	46	3	of	of	ADP
biomedich-939	46	4	selected	select	VERB
biomedich-939	46	5	functional	functional	ADJ
biomedich-939	46	6	and	and	CCONJ
biomedich-939	46	7	the	the	DET
biomedich-939	46	8	basis	basis	NOUN
biomedich-939	46	9	set	set	NOUN
biomedich-939	46	10	were	be	AUX
biomedich-939	46	11	based	base	VERB
biomedich-939	46	12	on	on	ADP
biomedich-939	46	13	its	its	PRON
biomedich-939	46	14	reliability	reliability	NOUN
biomedich-939	46	15	in	in	ADP
biomedich-939	46	16	published	publish	VERB
biomedich-939	46	17	reports	report	NOUN
biomedich-939	46	18	(	(	PUNCT
biomedich-939	46	19	haroon	haroon	PROPN
biomedich-939	46	20	et	et	PROPN
biomedich-939	46	21	al	al	PROPN
biomedich-939	46	22	.	.	PROPN
biomedich-939	46	23	,	,	PUNCT
biomedich-939	46	24	2019	2019	NUM
biomedich-939	46	25	)	)	PUNCT
biomedich-939	46	26	.	.	PUNCT
biomedich-939	47	1	a	a	DET
biomedich-939	47	2	single	single	ADJ
biomedich-939	47	3	-	-	PUNCT
biomedich-939	47	4	point	point	NOUN
biomedich-939	47	5	gasphase	gasphase	NOUN
biomedich-939	47	6	,	,	PUNCT
biomedich-939	47	7	waterphase	waterphase	NOUN
biomedich-939	47	8	and	and	CCONJ
biomedich-939	47	9	ethanol	ethanol	NOUN
biomedich-939	47	10	-	-	PUNCT
biomedich-939	47	11	phase	phase	NOUN
biomedich-939	47	12	optimizations	optimization	NOUN
biomedich-939	47	13	were	be	AUX
biomedich-939	47	14	carried	carry	VERB
biomedich-939	47	15	out	out	ADP
biomedich-939	47	16	using	use	VERB
biomedich-939	47	17	time	time	NOUN
biomedich-939	47	18	-	-	PUNCT
biomedich-939	47	19	dependent	dependent	ADJ
biomedich-939	47	20	density	density	NOUN
biomedich-939	47	21	functional	functional	ADJ
biomedich-939	47	22	theory	theory	NOUN
biomedich-939	47	23	(	(	PUNCT
biomedich-939	47	24	tddft	tddft	NOUN
biomedich-939	47	25	)	)	PUNCT
biomedich-939	47	26	13	13	NUM
biomedich-939	47	27	keyword	keyword	NOUN
biomedich-939	47	28	and	and	CCONJ
biomedich-939	47	29	solving	solve	VERB
biomedich-939	47	30	for	for	ADP
biomedich-939	47	31	50	50	NUM
biomedich-939	47	32	excited	excited	ADJ
biomedich-939	47	33	states	state	NOUN
biomedich-939	47	34	.	.	PUNCT
biomedich-939	48	1	all	all	DET
biomedich-939	48	2	calculations	calculation	NOUN
biomedich-939	48	3	in	in	ADP
biomedich-939	48	4	solvent	solvent	NOUN
biomedich-939	48	5	was	be	AUX
biomedich-939	48	6	performed	perform	VERB
biomedich-939	48	7	using	use	VERB
biomedich-939	48	8	the	the	DET
biomedich-939	48	9	cpcm	cpcm	ADJ
biomedich-939	48	10	keyword	keyword	NOUN
biomedich-939	48	11	together	together	ADV
biomedich-939	48	12	with	with	ADP
biomedich-939	48	13	the	the	DET
biomedich-939	48	14	smd	smd	NOUN
biomedich-939	48	15	solvent	solvent	NOUN
biomedich-939	48	16	model	model	NOUN
biomedich-939	48	17	(	(	PUNCT
biomedich-939	48	18	fleming	fleme	VERB
biomedich-939	48	19	et	et	PROPN
biomedich-939	48	20	al	al	PROPN
biomedich-939	48	21	.	.	PROPN
biomedich-939	48	22	,	,	PUNCT
biomedich-939	48	23	2011	2011	NUM
biomedich-939	48	24	;	;	PUNCT
biomedich-939	48	25	ho	ho	PROPN
biomedich-939	48	26	&	&	CCONJ
biomedich-939	48	27	ertem	ertem	PROPN
biomedich-939	48	28	,	,	PUNCT
biomedich-939	48	29	2016	2016	NUM
biomedich-939	48	30	)	)	PUNCT
biomedich-939	48	31	.	.	PUNCT
biomedich-939	49	1	drug	drug	NOUN
biomedich-939	49	2	-	-	PUNCT
biomedich-939	49	3	likeness	likeness	NOUN
biomedich-939	49	4	scores	score	NOUN
biomedich-939	49	5	and	and	CCONJ
biomedich-939	49	6	bioactivity	bioactivity	NOUN
biomedich-939	49	7	prediction	prediction	NOUN
biomedich-939	49	8	were	be	AUX
biomedich-939	49	9	carried	carry	VERB
biomedich-939	49	10	out	out	ADP
biomedich-939	49	11	using	use	VERB
biomedich-939	49	12	the	the	DET
biomedich-939	49	13	webserver	webserver	NOUN
biomedich-939	49	14	programs	program	NOUN
biomedich-939	49	15	such	such	ADJ
biomedich-939	49	16	as	as	ADP
biomedich-939	49	17	admet	admet	PROPN
biomedich-939	49	18	sar	sar	PROPN
biomedich-939	49	19	2	2	PROPN
biomedich-939	49	20	(	(	PUNCT
biomedich-939	49	21	available	available	ADJ
biomedich-939	49	22	at	at	ADP
biomedich-939	49	23	http://lmmd.ecust.edu.cn/admetsar2	http://lmmd.ecust.edu.cn/admetsar2	NOUN
biomedich-939	49	24	)	)	PUNCT
biomedich-939	49	25	and	and	CCONJ
biomedich-939	49	26	molinspiration	molinspiration	NOUN
biomedich-939	49	27	-cheminformatics	-cheminformatic	NOUN
biomedich-939	49	28	(	(	PUNCT
biomedich-939	49	29	available	available	ADJ
biomedich-939	49	30	at	at	ADP
biomedich-939	49	31	https://www.molinspiration.com/cgi-bin/properties	https://www.molinspiration.com/cgi-bin/propertie	NOUN
biomedich-939	49	32	)	)	PUNCT
biomedich-939	49	33	(	(	PUNCT
biomedich-939	49	34	voiculescu	voiculescu	NOUN
biomedich-939	49	35	et	et	PROPN
biomedich-939	49	36	al	al	PROPN
biomedich-939	49	37	.	.	PROPN
biomedich-939	49	38	,	,	PUNCT
biomedich-939	49	39	2022	2022	NUM
biomedich-939	49	40	)	)	PUNCT
biomedich-939	49	41	.	.	PUNCT
biomedich-939	50	1	result	result	NOUN
biomedich-939	50	2	and	and	CCONJ
biomedich-939	50	3	discussion	discussion	NOUN
biomedich-939	50	4	chemical	chemical	NOUN
biomedich-939	50	5	reactivity	reactivity	NOUN
biomedich-939	50	6	descriptors	descriptor	NOUN
biomedich-939	50	7	dft	dft	NOUN
biomedich-939	50	8	tools	tool	NOUN
biomedich-939	50	9	used	use	VERB
biomedich-939	50	10	in	in	ADP
biomedich-939	50	11	this	this	DET
biomedich-939	50	12	study	study	NOUN
biomedich-939	50	13	give	give	VERB
biomedich-939	50	14	a	a	DET
biomedich-939	50	15	concise	concise	ADJ
biomedich-939	50	16	structurechemical	structurechemical	ADJ
biomedich-939	50	17	reactivity	reactivity	NOUN
biomedich-939	50	18	report	report	NOUN
biomedich-939	50	19	of	of	ADP
biomedich-939	50	20	2	2	NUM
biomedich-939	50	21	-	-	PUNCT
biomedich-939	50	22	phenoxyquinoline-3carbaldehyde	phenoxyquinoline-3carbaldehyde	NOUN
biomedich-939	50	23	derivatives	derivative	NOUN
biomedich-939	50	24	(	(	PUNCT
biomedich-939	50	25	figure	figure	NOUN
biomedich-939	50	26	2	2	NUM
biomedich-939	50	27	)	)	PUNCT
biomedich-939	50	28	to	to	PART
biomedich-939	50	29	provide	provide	VERB
biomedich-939	50	30	an	an	DET
biomedich-939	50	31	understanding	understanding	NOUN
biomedich-939	50	32	of	of	ADP
biomedich-939	50	33	the	the	DET
biomedich-939	50	34	chemical	chemical	NOUN
biomedich-939	50	35	reactivity	reactivity	NOUN
biomedich-939	50	36	properties	property	NOUN
biomedich-939	50	37	whose	whose	DET
biomedich-939	50	38	descriptors	descriptor	NOUN
biomedich-939	50	39	are	be	AUX
biomedich-939	50	40	presented	present	VERB
biomedich-939	50	41	in	in	ADP
biomedich-939	50	42	table	table	NOUN
biomedich-939	50	43	1	1	NUM
biomedich-939	50	44	.	.	PUNCT
biomedich-939	50	45	frontier	frontier	NOUN
biomedich-939	50	46	molecular	molecular	ADJ
biomedich-939	50	47	orbitals	orbital	NOUN
biomedich-939	50	48	(	(	PUNCT
biomedich-939	50	49	fmos	fmos	PROPN
biomedich-939	50	50	)	)	PUNCT
biomedich-939	50	51	energies	energy	NOUN
biomedich-939	50	52	were	be	AUX
biomedich-939	50	53	used	use	VERB
biomedich-939	50	54	to	to	PART
biomedich-939	50	55	calculate	calculate	VERB
biomedich-939	50	56	these	these	DET
biomedich-939	50	57	chemical	chemical	ADJ
biomedich-939	50	58	reactivity	reactivity	NOUN
biomedich-939	50	59	descriptors	descriptor	NOUN
biomedich-939	50	60	obtained	obtain	VERB
biomedich-939	50	61	from	from	ADP
biomedich-939	50	62	conceptual	conceptual	ADJ
biomedich-939	50	63	dft	dft	PROPN
biomedich-939	50	64	.	.	PUNCT
biomedich-939	51	1	the	the	DET
biomedich-939	51	2	energy	energy	NOUN
biomedich-939	51	3	gap	gap	NOUN
biomedich-939	51	4	,	,	PUNCT
biomedich-939	51	5	egap	egap	PROPN
biomedich-939	51	6	is	be	AUX
biomedich-939	51	7	defined	define	VERB
biomedich-939	51	8	as	as	ADP
biomedich-939	51	9	the	the	DET
biomedich-939	51	10	energy	energy	NOUN
biomedich-939	51	11	difference	difference	NOUN
biomedich-939	51	12	between	between	ADP
biomedich-939	51	13	el	el	PROPN
biomedich-939	51	14	(	(	PUNCT
biomedich-939	51	15	the	the	DET
biomedich-939	51	16	lowest	lowest	ADV
biomedich-939	51	17	unoccupied	unoccupied	ADJ
biomedich-939	51	18	molecular	molecular	ADJ
biomedich-939	51	19	orbital	orbital	ADJ
biomedich-939	51	20	,	,	PUNCT
biomedich-939	51	21	lumo	lumo	NOUN
biomedich-939	51	22	)	)	PUNCT
biomedich-939	51	23	and	and	CCONJ
biomedich-939	51	24	eh	eh	INTJ
biomedich-939	51	25	(	(	PUNCT
biomedich-939	51	26	energy	energy	NOUN
biomedich-939	51	27	of	of	ADP
biomedich-939	51	28	the	the	DET
biomedich-939	51	29	highest	high	ADJ
biomedich-939	51	30	occupied	occupy	VERB
biomedich-939	51	31	molecular	molecular	ADJ
biomedich-939	51	32	orbital	orbital	ADJ
biomedich-939	51	33	,	,	PUNCT
biomedich-939	51	34	homo	homo	NOUN
biomedich-939	51	35	)	)	PUNCT
biomedich-939	51	36	which	which	PRON
biomedich-939	51	37	determines	determine	VERB
biomedich-939	51	38	the	the	DET
biomedich-939	51	39	chemical	chemical	NOUN
biomedich-939	51	40	reactivity	reactivity	NOUN
biomedich-939	51	41	and	and	CCONJ
biomedich-939	51	42	kinetic	kinetic	ADJ
biomedich-939	51	43	stability	stability	NOUN
biomedich-939	51	44	of	of	ADP
biomedich-939	51	45	the	the	DET
biomedich-939	51	46	organic	organic	ADJ
biomedich-939	51	47	molecule	molecule	NOUN
biomedich-939	51	48	.	.	PUNCT
biomedich-939	52	1	the	the	PRON
biomedich-939	52	2	lower	low	ADJ
biomedich-939	52	3	the	the	DET
biomedich-939	52	4	energy	energy	NOUN
biomedich-939	52	5	gap	gap	NOUN
biomedich-939	52	6	,	,	PUNCT
biomedich-939	52	7	the	the	DET
biomedich-939	52	8	more	more	ADV
biomedich-939	52	9	reactive	reactive	ADJ
biomedich-939	52	10	a	a	DET
biomedich-939	52	11	molecule	molecule	NOUN
biomedich-939	52	12	is	be	AUX
biomedich-939	52	13	,	,	PUNCT
biomedich-939	52	14	indicating	indicate	VERB
biomedich-939	52	15	the	the	DET
biomedich-939	52	16	compound	compound	NOUN
biomedich-939	52	17	is	be	AUX
biomedich-939	52	18	more	more	ADV
biomedich-939	52	19	susceptible	susceptible	ADJ
biomedich-939	52	20	to	to	ADP
biomedich-939	52	21	reacting	react	VERB
biomedich-939	52	22	with	with	ADP
biomedich-939	52	23	proteins	protein	NOUN
biomedich-939	52	24	or	or	CCONJ
biomedich-939	52	25	enzymes	enzyme	NOUN
biomedich-939	52	26	(	(	PUNCT
biomedich-939	52	27	miar	miar	NOUN
biomedich-939	52	28	et	et	PROPN
biomedich-939	52	29	al	al	PROPN
biomedich-939	52	30	.	.	PROPN
biomedich-939	52	31	,	,	PUNCT
biomedich-939	52	32	2021	2021	NUM
biomedich-939	52	33	)	)	PUNCT
biomedich-939	52	34	.	.	PUNCT
biomedich-939	53	1	the	the	DET
biomedich-939	53	2	results	result	NOUN
biomedich-939	53	3	of	of	ADP
biomedich-939	53	4	the	the	DET
biomedich-939	53	5	energy	energy	NOUN
biomedich-939	53	6	gaps	gap	NOUN
biomedich-939	53	7	(	(	PUNCT
biomedich-939	53	8	table	table	NOUN
biomedich-939	53	9	1	1	NUM
biomedich-939	53	10	and	and	CCONJ
biomedich-939	53	11	figure	figure	VERB
biomedich-939	53	12	3	3	NUM
biomedich-939	53	13	)	)	PUNCT
biomedich-939	53	14	showed	show	VERB
biomedich-939	53	15	slightly	slightly	ADV
biomedich-939	53	16	lower	low	ADJ
biomedich-939	53	17	energy	energy	NOUN
biomedich-939	53	18	values	value	NOUN
biomedich-939	53	19	in	in	ADP
biomedich-939	53	20	water	water	NOUN
biomedich-939	53	21	than	than	ADP
biomedich-939	53	22	in	in	ADP
biomedich-939	53	23	ethanol	ethanol	NOUN
biomedich-939	53	24	.	.	PUNCT
biomedich-939	54	1	since	since	SCONJ
biomedich-939	54	2	,	,	PUNCT
biomedich-939	54	3	the	the	DET
biomedich-939	54	4	preferred	preferred	ADJ
biomedich-939	54	5	medium	medium	NOUN
biomedich-939	54	6	of	of	ADP
biomedich-939	54	7	drug	drug	NOUN
biomedich-939	54	8	delivery	delivery	NOUN
biomedich-939	54	9	is	be	AUX
biomedich-939	54	10	water	water	NOUN
biomedich-939	54	11	,	,	PUNCT
biomedich-939	54	12	this	this	PRON
biomedich-939	54	13	depicts	depict	VERB
biomedich-939	54	14	the	the	DET
biomedich-939	54	15	highest	high	ADJ
biomedich-939	54	16	reactiveness	reactiveness	NOUN
biomedich-939	54	17	of	of	ADP
biomedich-939	54	18	the	the	DET
biomedich-939	54	19	2	2	NUM
biomedich-939	54	20	846	846	NUM
biomedich-939	54	21	biology	biology	NOUN
biomedich-939	54	22	,	,	PUNCT
biomedich-939	54	23	medicine	medicine	NOUN
biomedich-939	54	24	,	,	PUNCT
biomedich-939	54	25	&	&	CCONJ
biomedich-939	54	26	natural	natural	ADJ
biomedich-939	54	27	product	product	NOUN
biomedich-939	54	28	chemistry	chemistry	NOUN
biomedich-939	54	29	14	14	NUM
biomedich-939	54	30	(	(	PUNCT
biomedich-939	54	31	2	2	NUM
biomedich-939	54	32	)	)	PUNCT
biomedich-939	54	33	,	,	PUNCT
biomedich-939	54	34	2025	2025	NUM
biomedich-939	54	35	:	:	PUNCT
biomedich-939	54	36	843	843	NUM
biomedich-939	54	37	-	-	SYM
biomedich-939	54	38	856	856	NUM
biomedich-939	54	39	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	54	40	in	in	ADP
biomedich-939	54	41	water	water	NOUN
biomedich-939	54	42	,	,	PUNCT
biomedich-939	54	43	with	with	ADP
biomedich-939	54	44	7	7	NUM
biomedich-939	54	45	and	and	CCONJ
biomedich-939	54	46	3	3	NUM
biomedich-939	54	47	having	have	VERB
biomedich-939	54	48	the	the	DET
biomedich-939	54	49	lowest	low	ADJ
biomedich-939	54	50	egap	egap	NOUN
biomedich-939	54	51	of	of	ADP
biomedich-939	54	52	3.381	3.381	NUM
biomedich-939	54	53	ev	ev	NOUN
biomedich-939	54	54	and	and	CCONJ
biomedich-939	54	55	3.79	3.79	NUM
biomedich-939	54	56	ev	ev	NUM
biomedich-939	54	57	respectively	respectively	ADV
biomedich-939	54	58	.	.	PUNCT
biomedich-939	55	1	the	the	DET
biomedich-939	55	2	concentration	concentration	NOUN
biomedich-939	55	3	of	of	ADP
biomedich-939	55	4	the	the	DET
biomedich-939	55	5	molecules	molecule	NOUN
biomedich-939	55	6	is	be	AUX
biomedich-939	55	7	proportionately	proportionately	ADV
biomedich-939	55	8	the	the	DET
biomedich-939	55	9	inverse	inverse	NOUN
biomedich-939	55	10	of	of	ADP
biomedich-939	55	11	the	the	DET
biomedich-939	55	12	energy	energy	NOUN
biomedich-939	55	13	gap	gap	NOUN
biomedich-939	55	14	.	.	PUNCT
biomedich-939	56	1	that	that	PRON
biomedich-939	56	2	is	be	AUX
biomedich-939	56	3	,	,	PUNCT
biomedich-939	56	4	the	the	PRON
biomedich-939	56	5	lower	low	ADJ
biomedich-939	56	6	the	the	DET
biomedich-939	56	7	energy	energy	NOUN
biomedich-939	56	8	gap	gap	NOUN
biomedich-939	56	9	the	the	PRON
biomedich-939	56	10	higher	high	ADJ
biomedich-939	56	11	the	the	DET
biomedich-939	56	12	concentration	concentration	NOUN
biomedich-939	56	13	of	of	ADP
biomedich-939	56	14	the	the	DET
biomedich-939	56	15	molecule	molecule	NOUN
biomedich-939	56	16	in	in	ADP
biomedich-939	56	17	water	water	NOUN
biomedich-939	56	18	solution	solution	NOUN
biomedich-939	56	19	and	and	CCONJ
biomedich-939	56	20	therefore	therefore	ADV
biomedich-939	56	21	it	it	PRON
biomedich-939	56	22	shows	show	VERB
biomedich-939	56	23	a	a	DET
biomedich-939	56	24	greater	great	ADJ
biomedich-939	56	25	activity	activity	NOUN
biomedich-939	56	26	of	of	ADP
biomedich-939	56	27	the	the	DET
biomedich-939	56	28	2phenoxyquinolines	2phenoxyquinolines	PROPN
biomedich-939	56	29	in	in	ADP
biomedich-939	56	30	aqueous	aqueous	ADJ
biomedich-939	56	31	medium	medium	NOUN
biomedich-939	56	32	.	.	PUNCT
biomedich-939	57	1	the	the	DET
biomedich-939	57	2	difference	difference	NOUN
biomedich-939	57	3	in	in	ADP
biomedich-939	57	4	the	the	DET
biomedich-939	57	5	energy	energy	NOUN
biomedich-939	57	6	gap	gap	NOUN
biomedich-939	57	7	may	may	AUX
biomedich-939	57	8	be	be	AUX
biomedich-939	57	9	mostly	mostly	ADV
biomedich-939	57	10	attributed	attribute	VERB
biomedich-939	57	11	to	to	ADP
biomedich-939	57	12	the	the	DET
biomedich-939	57	13	differences	difference	NOUN
biomedich-939	57	14	in	in	ADP
biomedich-939	57	15	their	their	PRON
biomedich-939	57	16	functional	functional	ADJ
biomedich-939	57	17	groups	group	NOUN
biomedich-939	57	18	(	(	PUNCT
biomedich-939	57	19	table	table	NOUN
biomedich-939	57	20	s1	s1	NOUN
biomedich-939	57	21	)	)	PUNCT
biomedich-939	57	22	.	.	PUNCT
biomedich-939	58	1	this	this	DET
biomedich-939	58	2	difference	difference	NOUN
biomedich-939	58	3	can	can	AUX
biomedich-939	58	4	be	be	AUX
biomedich-939	58	5	attributed	attribute	VERB
biomedich-939	58	6	to	to	ADP
biomedich-939	58	7	the	the	DET
biomedich-939	58	8	acetoxyl	acetoxyl	PROPN
biomedich-939	58	9	and	and	CCONJ
biomedich-939	58	10	benzoyl	benzoyl	ADJ
biomedich-939	58	11	substituents	substituent	NOUN
biomedich-939	58	12	at	at	ADP
biomedich-939	58	13	para	para	NOUN
biomedich-939	58	14	position	position	NOUN
biomedich-939	58	15	of	of	ADP
biomedich-939	58	16	the	the	DET
biomedich-939	58	17	phenoxy	phenoxy	PROPN
biomedich-939	58	18	group	group	NOUN
biomedich-939	58	19	.	.	PUNCT
biomedich-939	59	1	in	in	ADP
biomedich-939	59	2	compounds	compound	NOUN
biomedich-939	59	3	3	3	NUM
biomedich-939	59	4	,	,	PUNCT
biomedich-939	59	5	7	7	NUM
biomedich-939	59	6	and	and	CCONJ
biomedich-939	59	7	8	8	NUM
biomedich-939	59	8	,	,	PUNCT
biomedich-939	59	9	the	the	DET
biomedich-939	59	10	main	main	ADJ
biomedich-939	59	11	chromone	chromone	NOUN
biomedich-939	59	12	skeleton	skeleton	NOUN
biomedich-939	59	13	(	(	PUNCT
biomedich-939	59	14	quinoline	quinoline	NOUN
biomedich-939	59	15	)	)	PUNCT
biomedich-939	59	16	has	have	VERB
biomedich-939	59	17	both	both	PRON
biomedich-939	59	18	electron	electron	NOUN
biomedich-939	59	19	withdrawing	withdrawing	NOUN
biomedich-939	59	20	and	and	CCONJ
biomedich-939	59	21	electron	electron	NOUN
biomedich-939	59	22	donating	donate	VERB
biomedich-939	59	23	substituents	substituent	NOUN
biomedich-939	59	24	attached	attach	VERB
biomedich-939	59	25	to	to	ADP
biomedich-939	59	26	it	it	PRON
biomedich-939	59	27	.	.	PUNCT
biomedich-939	60	1	these	these	DET
biomedich-939	60	2	substituents	substituent	NOUN
biomedich-939	60	3	may	may	AUX
biomedich-939	60	4	increase	increase	VERB
biomedich-939	60	5	or	or	CCONJ
biomedich-939	60	6	decrease	decrease	VERB
biomedich-939	60	7	the	the	DET
biomedich-939	60	8	electron	electron	NOUN
biomedich-939	60	9	density	density	NOUN
biomedich-939	60	10	in	in	ADP
biomedich-939	60	11	the	the	DET
biomedich-939	60	12	quinoline	quinoline	NOUN
biomedich-939	60	13	ring	ring	NOUN
biomedich-939	60	14	thereby	thereby	ADV
biomedich-939	60	15	activating	activate	VERB
biomedich-939	60	16	or	or	CCONJ
biomedich-939	60	17	deactivating	deactivate	VERB
biomedich-939	60	18	the	the	DET
biomedich-939	60	19	ring	ring	NOUN
biomedich-939	60	20	.	.	PUNCT
biomedich-939	61	1	the	the	DET
biomedich-939	61	2	lower	low	ADJ
biomedich-939	61	3	energy	energy	NOUN
biomedich-939	61	4	gap	gap	NOUN
biomedich-939	61	5	for	for	ADP
biomedich-939	61	6	3	3	NUM
biomedich-939	61	7	and	and	CCONJ
biomedich-939	61	8	8	8	NUM
biomedich-939	61	9	may	may	AUX
biomedich-939	61	10	be	be	AUX
biomedich-939	61	11	attributed	attribute	VERB
biomedich-939	61	12	to	to	ADP
biomedich-939	61	13	f	f	PROPN
biomedich-939	61	14	which	which	PRON
biomedich-939	61	15	shows	show	VERB
biomedich-939	61	16	a	a	DET
biomedich-939	61	17	negative	negative	ADJ
biomedich-939	61	18	inductive	inductive	ADJ
biomedich-939	61	19	effect	effect	NOUN
biomedich-939	61	20	due	due	ADP
biomedich-939	61	21	to	to	ADP
biomedich-939	61	22	its	its	PRON
biomedich-939	61	23	high	high	ADJ
biomedich-939	61	24	electronegativity	electronegativity	NOUN
biomedich-939	61	25	and	and	CCONJ
biomedich-939	61	26	withdraws	withdraw	VERB
biomedich-939	61	27	the	the	DET
biomedich-939	61	28	electron	electron	NOUN
biomedich-939	61	29	density	density	NOUN
biomedich-939	61	30	from	from	ADP
biomedich-939	61	31	the	the	DET
biomedich-939	61	32	quinoline	quinoline	NOUN
biomedich-939	61	33	ring	ring	NOUN
biomedich-939	61	34	,	,	PUNCT
biomedich-939	61	35	so	so	SCONJ
biomedich-939	61	36	it	it	PRON
biomedich-939	61	37	deactivating	deactivate	VERB
biomedich-939	61	38	the	the	DET
biomedich-939	61	39	group	group	NOUN
biomedich-939	61	40	.	.	PUNCT
biomedich-939	62	1	the	the	DET
biomedich-939	62	2	more	more	ADV
biomedich-939	62	3	electrophilic	electrophilic	ADJ
biomedich-939	62	4	benzyl	benzyl	NOUN
biomedich-939	62	5	group	group	NOUN
biomedich-939	62	6	in	in	ADP
biomedich-939	62	7	the	the	DET
biomedich-939	62	8	chromone	chromone	NOUN
biomedich-939	62	9	backbone	backbone	NOUN
biomedich-939	62	10	allows	allow	VERB
biomedich-939	62	11	electronic	electronic	ADJ
biomedich-939	62	12	interactions	interaction	NOUN
biomedich-939	62	13	that	that	PRON
biomedich-939	62	14	are	be	AUX
biomedich-939	62	15	pivotal	pivotal	ADJ
biomedich-939	62	16	to	to	ADP
biomedich-939	62	17	the	the	DET
biomedich-939	62	18	quinoline	quinoline	NOUN
biomedich-939	62	19	reactivity	reactivity	NOUN
biomedich-939	62	20	.	.	PUNCT
biomedich-939	63	1	also	also	ADV
biomedich-939	63	2	,	,	PUNCT
biomedich-939	63	3	the	the	DET
biomedich-939	63	4	methoxyl	methoxyl	NOUN
biomedich-939	63	5	groups	group	NOUN
biomedich-939	63	6	on	on	ADP
biomedich-939	63	7	the	the	DET
biomedich-939	63	8	chromone	chromone	NOUN
biomedich-939	63	9	structure	structure	NOUN
biomedich-939	63	10	of	of	ADP
biomedich-939	63	11	compound	compound	NOUN
biomedich-939	63	12	7	7	NUM
biomedich-939	63	13	which	which	PRON
biomedich-939	63	14	has	have	VERB
biomedich-939	63	15	the	the	DET
biomedich-939	63	16	lowest	low	ADJ
biomedich-939	63	17	energy	energy	NOUN
biomedich-939	63	18	gap	gap	NOUN
biomedich-939	63	19	(	(	PUNCT
biomedich-939	63	20	3.381	3.381	NUM
biomedich-939	63	21	ev	ev	NOUN
biomedich-939	63	22	)	)	PUNCT
biomedich-939	63	23	activate	activate	VERB
biomedich-939	63	24	the	the	DET
biomedich-939	63	25	benzene	benzene	NOUN
biomedich-939	63	26	ring	ring	NOUN
biomedich-939	63	27	towards	towards	ADP
biomedich-939	63	28	electrophilic	electrophilic	ADJ
biomedich-939	63	29	substitution	substitution	NOUN
biomedich-939	63	30	and	and	CCONJ
biomedich-939	63	31	this	this	PRON
biomedich-939	63	32	is	be	AUX
biomedich-939	63	33	also	also	ADV
biomedich-939	63	34	favourable	favourable	ADJ
biomedich-939	63	35	for	for	ADP
biomedich-939	63	36	the	the	DET
biomedich-939	63	37	radical	radical	ADJ
biomedich-939	63	38	scavenging	scavenging	ADJ
biomedich-939	63	39	activity	activity	NOUN
biomedich-939	63	40	of	of	ADP
biomedich-939	63	41	the	the	DET
biomedich-939	63	42	quinoline	quinoline	NOUN
biomedich-939	63	43	ring	ring	NOUN
biomedich-939	63	44	.	.	PUNCT
biomedich-939	64	1	the	the	DET
biomedich-939	64	2	feasibility	feasibility	NOUN
biomedich-939	64	3	of	of	ADP
biomedich-939	64	4	a	a	DET
biomedich-939	64	5	molecular	molecular	ADJ
biomedich-939	64	6	system	system	NOUN
biomedich-939	64	7	to	to	PART
biomedich-939	64	8	exchange	exchange	VERB
biomedich-939	64	9	electron	electron	NOUN
biomedich-939	64	10	density	density	NOUN
biomedich-939	64	11	or	or	CCONJ
biomedich-939	64	12	an	an	DET
biomedich-939	64	13	electron	electron	NOUN
biomedich-939	64	14	escaping	escape	VERB
biomedich-939	64	15	from	from	ADP
biomedich-939	64	16	such	such	ADJ
biomedich-939	64	17	system	system	NOUN
biomedich-939	64	18	to	to	ADP
biomedich-939	64	19	the	the	DET
biomedich-939	64	20	surrounding	surround	VERB
biomedich-939	64	21	environment	environment	NOUN
biomedich-939	64	22	at	at	ADP
biomedich-939	64	23	the	the	DET
biomedich-939	64	24	ground	ground	NOUN
biomedich-939	64	25	state	state	NOUN
biomedich-939	64	26	can	can	AUX
biomedich-939	64	27	be	be	AUX
biomedich-939	64	28	expressed	express	VERB
biomedich-939	64	29	as	as	ADP
biomedich-939	64	30	the	the	DET
biomedich-939	64	31	energy	energy	NOUN
biomedich-939	64	32	changes	change	NOUN
biomedich-939	64	33	of	of	ADP
biomedich-939	64	34	the	the	DET
biomedich-939	64	35	molecular	molecular	ADJ
biomedich-939	64	36	system	system	NOUN
biomedich-939	64	37	with	with	ADP
biomedich-939	64	38	respect	respect	NOUN
biomedich-939	64	39	to	to	ADP
biomedich-939	64	40	the	the	DET
biomedich-939	64	41	number	number	NOUN
biomedich-939	64	42	of	of	ADP
biomedich-939	64	43	electrons	electron	NOUN
biomedich-939	64	44	at	at	ADP
biomedich-939	64	45	a	a	DET
biomedich-939	64	46	fixed	fix	VERB
biomedich-939	64	47	external	external	ADJ
biomedich-939	64	48	potential	potential	NOUN
biomedich-939	64	49	,	,	PUNCT
biomedich-939	64	50	µ	µ	X
biomedich-939	64	51	(	(	PUNCT
biomedich-939	64	52	domingo	domingo	PROPN
biomedich-939	64	53	et	et	PROPN
biomedich-939	64	54	al	al	PROPN
biomedich-939	64	55	.	.	PROPN
biomedich-939	64	56	,	,	PUNCT
biomedich-939	64	57	2016	2016	NUM
biomedich-939	64	58	)	)	PUNCT
biomedich-939	64	59	.	.	PUNCT
biomedich-939	65	1	figure	figure	NOUN
biomedich-939	65	2	2	2	NUM
biomedich-939	65	3	.	.	PUNCT
biomedich-939	65	4	structures	structure	NOUN
biomedich-939	65	5	of	of	ADP
biomedich-939	65	6	synthesized	synthesize	VERB
biomedich-939	65	7	phenoxyquinoline	phenoxyquinoline	NOUN
biomedich-939	65	8	compounds	compound	NOUN
biomedich-939	65	9	investigated	investigate	VERB
biomedich-939	65	10	.	.	PUNCT
biomedich-939	66	1	the	the	DET
biomedich-939	66	2	calculated	calculate	VERB
biomedich-939	66	3	electronic	electronic	ADJ
biomedich-939	66	4	chemical	chemical	NOUN
biomedich-939	66	5	potential	potential	NOUN
biomedich-939	66	6	of	of	ADP
biomedich-939	66	7	the	the	DET
biomedich-939	66	8	molecules	molecule	NOUN
biomedich-939	66	9	shows	show	VERB
biomedich-939	66	10	no	no	DET
biomedich-939	66	11	significant	significant	ADJ
biomedich-939	66	12	difference	difference	NOUN
biomedich-939	66	13	for	for	ADP
biomedich-939	66	14	the	the	DET
biomedich-939	66	15	2phenoxyuinolines	2phenoxyuinolines	PROPN
biomedich-939	66	16	.	.	PUNCT
biomedich-939	67	1	in	in	ADP
biomedich-939	67	2	water	water	NOUN
biomedich-939	67	3	,	,	PUNCT
biomedich-939	67	4	the	the	DET
biomedich-939	67	5	chemical	chemical	ADJ
biomedich-939	67	6	potential	potential	ADJ
biomedich-939	67	7	values	value	NOUN
biomedich-939	67	8	range	range	VERB
biomedich-939	67	9	from	from	ADP
biomedich-939	67	10	-4.688	-4.688	PUNCT
biomedich-939	67	11	ev	ev	X
biomedich-939	67	12	(	(	PUNCT
biomedich-939	67	13	8)	8)	NUM
biomedich-939	67	14	to	to	ADP
biomedich-939	67	15	-4.301	-4.301	NUM
biomedich-939	67	16	ev	ev	X
biomedich-939	67	17	(	(	PUNCT
biomedich-939	67	18	7	7	NUM
biomedich-939	67	19	)	)	PUNCT
biomedich-939	67	20	while	while	SCONJ
biomedich-939	67	21	in	in	ADP
biomedich-939	67	22	ethanol	ethanol	NOUN
biomedich-939	67	23	,	,	PUNCT
biomedich-939	67	24	it	it	PRON
biomedich-939	67	25	ranges	range	VERB
biomedich-939	67	26	from	from	ADP
biomedich-939	67	27	-4.681ev	-4.681ev	PROPN
biomedich-939	67	28	(	(	PUNCT
biomedich-939	67	29	8)	8)	NUM
biomedich-939	67	30	to	to	ADP
biomedich-939	67	31	-4.294	-4.294	PRON
biomedich-939	67	32	ev	ev	X
biomedich-939	67	33	(	(	PUNCT
biomedich-939	67	34	7	7	NUM
biomedich-939	67	35	)	)	PUNCT
biomedich-939	67	36	with	with	ADP
biomedich-939	67	37	both	both	DET
biomedich-939	67	38	media	medium	NOUN
biomedich-939	67	39	having	have	VERB
biomedich-939	67	40	the	the	DET
biomedich-939	67	41	ascending	ascend	VERB
biomedich-939	67	42	and	and	CCONJ
biomedich-939	67	43	descending	descend	VERB
biomedich-939	67	44	order	order	NOUN
biomedich-939	67	45	of	of	ADP
biomedich-939	67	46	7	7	NUM
biomedich-939	67	47	,	,	PUNCT
biomedich-939	67	48	3	3	NUM
biomedich-939	67	49	,	,	PUNCT
biomedich-939	67	50	5	5	NUM
biomedich-939	67	51	,	,	PUNCT
biomedich-939	67	52	8	8	NUM
biomedich-939	67	53	,	,	PUNCT
biomedich-939	67	54	1	1	NUM
biomedich-939	67	55	,	,	PUNCT
biomedich-939	67	56	2	2	NUM
biomedich-939	67	57	,	,	PUNCT
biomedich-939	67	58	6	6	NUM
biomedich-939	67	59	and	and	CCONJ
biomedich-939	67	60	4	4	NUM
biomedich-939	67	61	hardness	hardness	ADJ
biomedich-939	67	62	and	and	CCONJ
biomedich-939	67	63	softness	softness	NOUN
biomedich-939	67	64	,	,	PUNCT
biomedich-939	67	65	η	η	PROPN
biomedich-939	67	66	and	and	CCONJ
biomedich-939	67	67	s	s	PROPN
biomedich-939	67	68	respectively	respectively	ADV
biomedich-939	67	69	define	define	VERB
biomedich-939	67	70	the	the	DET
biomedich-939	67	71	extent	extent	NOUN
biomedich-939	67	72	of	of	ADP
biomedich-939	67	73	resistance	resistance	NOUN
biomedich-939	67	74	and	and	CCONJ
biomedich-939	67	75	susceptibility	susceptibility	NOUN
biomedich-939	67	76	to	to	PART
biomedich-939	67	77	polarization	polarization	NOUN
biomedich-939	67	78	or	or	CCONJ
biomedich-939	67	79	transfer	transfer	NOUN
biomedich-939	67	80	of	of	ADP
biomedich-939	67	81	electron	electron	NOUN
biomedich-939	67	82	cloud	cloud	NOUN
biomedich-939	67	83	of	of	ADP
biomedich-939	67	84	atoms	atom	NOUN
biomedich-939	67	85	,	,	PUNCT
biomedich-939	67	86	ions	ion	NOUN
biomedich-939	67	87	or	or	CCONJ
biomedich-939	67	88	molecules	molecule	NOUN
biomedich-939	67	89	in	in	ADP
biomedich-939	67	90	response	response	NOUN
biomedich-939	67	91	to	to	ADP
biomedich-939	67	92	a	a	DET
biomedich-939	67	93	chemical	chemical	NOUN
biomedich-939	67	94	process	process	NOUN
biomedich-939	67	95	(	(	PUNCT
biomedich-939	67	96	islam	islam	PROPN
biomedich-939	67	97	&	&	CCONJ
biomedich-939	67	98	ghosh	ghosh	PROPN
biomedich-939	67	99	,	,	PUNCT
biomedich-939	67	100	2011	2011	NUM
biomedich-939	67	101	)	)	PUNCT
biomedich-939	67	102	.	.	PUNCT
biomedich-939	68	1	these	these	DET
biomedich-939	68	2	periodic	periodic	ADJ
biomedich-939	68	3	properties	property	NOUN
biomedich-939	68	4	calculated	calculate	VERB
biomedich-939	68	5	as	as	ADP
biomedich-939	68	6	global	global	ADJ
biomedich-939	68	7	softness	softness	NOUN
biomedich-939	68	8	,	,	PUNCT
biomedich-939	68	9	s	s	VERB
biomedich-939	68	10	are	be	AUX
biomedich-939	68	11	the	the	DET
biomedich-939	68	12	inverse	inverse	NOUN
biomedich-939	68	13	of	of	ADP
biomedich-939	68	14	global	global	ADJ
biomedich-939	68	15	hardness	hardness	NOUN
biomedich-939	68	16	,	,	PUNCT
biomedich-939	68	17	η	η	PROPN
biomedich-939	68	18	.	.	PROPN
biomedich-939	68	19	compound	compound	NOUN
biomedich-939	68	20	7	7	NUM
biomedich-939	68	21	shows	show	VERB
biomedich-939	68	22	the	the	DET
biomedich-939	68	23	most	most	ADV
biomedich-939	68	24	minor	minor	ADJ
biomedich-939	68	25	resistance	resistance	NOUN
biomedich-939	68	26	or	or	CCONJ
biomedich-939	68	27	highest	high	ADJ
biomedich-939	68	28	susceptibility	susceptibility	NOUN
biomedich-939	68	29	to	to	PART
biomedich-939	68	30	charge	charge	VERB
biomedich-939	68	31	or	or	CCONJ
biomedich-939	68	32	electron	electron	NOUN
biomedich-939	68	33	transfer	transfer	NOUN
biomedich-939	68	34	with	with	ADP
biomedich-939	68	35	η	η	PROPN
biomedich-939	68	36	and	and	CCONJ
biomedich-939	68	37	s	s	PROPN
biomedich-939	68	38	values	value	NOUN
biomedich-939	68	39	(	(	PUNCT
biomedich-939	68	40	1.691	1.691	NUM
biomedich-939	68	41	ev	ev	NOUN
biomedich-939	68	42	and	and	CCONJ
biomedich-939	68	43	0.592	0.592	NUM
biomedich-939	68	44	ev	ev	NOUN
biomedich-939	68	45	)	)	PUNCT
biomedich-939	68	46	in	in	ADP
biomedich-939	68	47	water	water	NOUN
biomedich-939	68	48	respectively	respectively	ADV
biomedich-939	68	49	.	.	PUNCT
biomedich-939	69	1	conversely	conversely	ADV
biomedich-939	69	2	,	,	PUNCT
biomedich-939	69	3	compound	compound	NOUN
biomedich-939	69	4	4	4	NUM
biomedich-939	69	5	has	have	VERB
biomedich-939	69	6	η	η	NOUN
biomedich-939	69	7	value	value	NOUN
biomedich-939	69	8	of	of	ADP
biomedich-939	69	9	2.106	2.106	NUM
biomedich-939	69	10	ev	ev	NOUN
biomedich-939	69	11	and	and	CCONJ
biomedich-939	69	12	s	s	NOUN
biomedich-939	69	13	value	value	NOUN
biomedich-939	69	14	of	of	ADP
biomedich-939	69	15	0.475	0.475	NUM
biomedich-939	69	16	ev	ev	NOUN
biomedich-939	69	17	in	in	ADP
biomedich-939	69	18	aqueous	aqueous	ADJ
biomedich-939	69	19	medium	medium	NOUN
biomedich-939	69	20	.	.	PUNCT
biomedich-939	70	1	therefore	therefore	ADV
biomedich-939	70	2	,	,	PUNCT
biomedich-939	70	3	of	of	ADP
biomedich-939	70	4	all	all	DET
biomedich-939	70	5	the	the	DET
biomedich-939	70	6	2	2	NUM
biomedich-939	70	7	-	-	PUNCT
biomedich-939	70	8	phenoxyuinolines	phenoxyuinoline	NOUN
biomedich-939	70	9	compounds	compound	NOUN
biomedich-939	70	10	,	,	PUNCT
biomedich-939	70	11	7	7	NUM
biomedich-939	70	12	is	be	AUX
biomedich-939	70	13	the	the	DET
biomedich-939	70	14	most	most	ADV
biomedich-939	70	15	susceptible	susceptible	ADJ
biomedich-939	70	16	to	to	ADP
biomedich-939	70	17	electron	electron	NOUN
biomedich-939	70	18	transfer	transfer	NOUN
biomedich-939	70	19	and	and	CCONJ
biomedich-939	70	20	the	the	DET
biomedich-939	70	21	most	most	ADV
biomedich-939	70	22	chemically	chemically	ADV
biomedich-939	70	23	reactive	reactive	ADJ
biomedich-939	70	24	in	in	ADP
biomedich-939	70	25	aqeous	aqeous	ADJ
biomedich-939	70	26	medium	medium	NOUN
biomedich-939	70	27	while	while	SCONJ
biomedich-939	70	28	compound	compound	NOUN
biomedich-939	70	29	4	4	NUM
biomedich-939	70	30	poses	pose	VERB
biomedich-939	70	31	the	the	DET
biomedich-939	70	32	highest	high	ADJ
biomedich-939	70	33	resistance	resistance	NOUN
biomedich-939	70	34	to	to	ADP
biomedich-939	70	35	the	the	DET
biomedich-939	70	36	transfer	transfer	NOUN
biomedich-939	70	37	of	of	ADP
biomedich-939	70	38	electron	electron	NOUN
biomedich-939	70	39	density	density	NOUN
biomedich-939	70	40	in	in	ADP
biomedich-939	70	41	the	the	DET
biomedich-939	70	42	medium	medium	NOUN
biomedich-939	70	43	and	and	CCONJ
biomedich-939	70	44	hence	hence	ADV
biomedich-939	70	45	,	,	PUNCT
biomedich-939	70	46	the	the	DET
biomedich-939	70	47	least	least	ADJ
biomedich-939	70	48	reactive	reactive	ADJ
biomedich-939	70	49	.	.	PUNCT
biomedich-939	71	1	electronegativity	electronegativity	NOUN
biomedich-939	71	2	,	,	PUNCT
biomedich-939	71	3	χ	χ	X
biomedich-939	71	4	,	,	PUNCT
biomedich-939	71	5	represents	represent	VERB
biomedich-939	71	6	electron	electron	NOUN
biomedich-939	71	7	attraction	attraction	NOUN
biomedich-939	71	8	power	power	NOUN
biomedich-939	71	9	of	of	ADP
biomedich-939	71	10	an	an	DET
biomedich-939	71	11	atom	atom	NOUN
biomedich-939	71	12	in	in	ADP
biomedich-939	71	13	a	a	DET
biomedich-939	71	14	molecule	molecule	NOUN
biomedich-939	71	15	towards	towards	ADP
biomedich-939	71	16	itself	itself	PRON
biomedich-939	71	17	or	or	CCONJ
biomedich-939	71	18	a	a	DET
biomedich-939	71	19	measure	measure	NOUN
biomedich-939	71	20	of	of	ADP
biomedich-939	71	21	molecular	molecular	ADJ
biomedich-939	71	22	electron	electron	NOUN
biomedich-939	71	23	distribution.23	distribution.23	PRON
biomedich-939	71	24	the	the	DET
biomedich-939	71	25	highly	highly	ADV
biomedich-939	71	26	probable	probable	ADJ
biomedich-939	71	27	electron	electron	NOUN
biomedich-939	71	28	acceptability	acceptability	NOUN
biomedich-939	71	29	of	of	ADP
biomedich-939	71	30	these	these	DET
biomedich-939	71	31	molecules	molecule	NOUN
biomedich-939	71	32	was	be	AUX
biomedich-939	71	33	indicated	indicate	VERB
biomedich-939	71	34	by	by	ADP
biomedich-939	71	35	high	high	ADJ
biomedich-939	71	36	electronegativity	electronegativity	NOUN
biomedich-939	71	37	values	value	NOUN
biomedich-939	71	38	.	.	PUNCT
biomedich-939	72	1	compounds	compound	NOUN
biomedich-939	72	2	8	8	NUM
biomedich-939	72	3	and	and	CCONJ
biomedich-939	72	4	6	6	NUM
biomedich-939	72	5	had	have	VERB
biomedich-939	72	6	the	the	DET
biomedich-939	72	7	highest	high	ADJ
biomedich-939	72	8	χ	χ	NOUN
biomedich-939	72	9	value	value	NOUN
biomedich-939	72	10	(	(	PUNCT
biomedich-939	72	11	4.688	4.688	NUM
biomedich-939	72	12	ev	ev	X
biomedich-939	72	13	and	and	CCONJ
biomedich-939	72	14	4.681	4.681	NUM
biomedich-939	72	15	ev	ev	NOUN
biomedich-939	72	16	)	)	PUNCT
biomedich-939	72	17	in	in	ADP
biomedich-939	72	18	aqueous	aqueous	ADJ
biomedich-939	72	19	medium	medium	NOUN
biomedich-939	72	20	while	while	SCONJ
biomedich-939	72	21	7	7	NUM
biomedich-939	72	22	had	have	VERB
biomedich-939	72	23	the	the	DET
biomedich-939	72	24	lowest	low	ADJ
biomedich-939	72	25	(	(	PUNCT
biomedich-939	72	26	4.301	4.301	NUM
biomedich-939	72	27	ev	ev	NOUN
biomedich-939	72	28	)	)	PUNCT
biomedich-939	72	29	.	.	PUNCT
biomedich-939	73	1	a	a	DET
biomedich-939	73	2	possible	possible	ADJ
biomedich-939	73	3	explanation	explanation	NOUN
biomedich-939	73	4	for	for	ADP
biomedich-939	73	5	high	high	ADJ
biomedich-939	73	6	electronegativity	electronegativity	NOUN
biomedich-939	73	7	for	for	ADP
biomedich-939	73	8	compound	compound	NOUN
biomedich-939	73	9	8	8	NUM
biomedich-939	73	10	and	and	CCONJ
biomedich-939	73	11	6	6	NUM
biomedich-939	73	12	is	be	AUX
biomedich-939	73	13	the	the	DET
biomedich-939	73	14	presence	presence	NOUN
biomedich-939	73	15	of	of	ADP
biomedich-939	73	16	fluoro	fluoro	NOUN
biomedich-939	73	17	group	group	NOUN
biomedich-939	73	18	(	(	PUNCT
biomedich-939	73	19	a	a	DET
biomedich-939	73	20	deactivating	deactivating	ADJ
biomedich-939	73	21	group	group	NOUN
biomedich-939	73	22	)	)	PUNCT
biomedich-939	73	23	with	with	ADP
biomedich-939	73	24	high	high	ADJ
biomedich-939	73	25	inductive	inductive	ADJ
biomedich-939	73	26	effect	effect	NOUN
biomedich-939	73	27	.	.	PUNCT
biomedich-939	74	1	compound	compound	NOUN
biomedich-939	74	2	7	7	NUM
biomedich-939	74	3	,	,	PUNCT
biomedich-939	74	4	on	on	ADP
biomedich-939	74	5	the	the	DET
biomedich-939	74	6	other	other	ADJ
biomedich-939	74	7	hand	hand	NOUN
biomedich-939	74	8	has	have	VERB
biomedich-939	74	9	an	an	DET
biomedich-939	74	10	activating	activating	ADJ
biomedich-939	74	11	group	group	NOUN
biomedich-939	74	12	that	that	PRON
biomedich-939	74	13	is	be	AUX
biomedich-939	74	14	mostly	mostly	ADV
biomedich-939	74	15	resonance	resonance	NOUN
biomedich-939	74	16	donors	donor	NOUN
biomedich-939	74	17	(	(	PUNCT
biomedich-939	74	18	+	+	NOUN
biomedich-939	74	19	m	m	NOUN
biomedich-939	74	20	)	)	PUNCT
biomedich-939	74	21	,	,	PUNCT
biomedich-939	74	22	that	that	ADV
biomedich-939	74	23	is	is	ADV
biomedich-939	74	24	,	,	PUNCT
biomedich-939	74	25	aina	aina	PROPN
biomedich-939	74	26	et	et	PROPN
biomedich-939	74	27	al	al	PROPN
biomedich-939	74	28	.	.	PROPN
biomedich-939	75	1	–	–	PUNCT
biomedich-939	75	2	dft	dft	PROPN
biomedich-939	75	3	study	study	NOUN
biomedich-939	75	4	and	and	CCONJ
biomedich-939	75	5	admet	admet	PROPN
biomedich-939	75	6	investigation	investigation	NOUN
biomedich-939	75	7	of	of	ADP
biomedich-939	75	8	bioactive	bioactive	ADJ
biomedich-939	75	9	2	2	NUM
biomedich-939	75	10	-	-	PUNCT
biomedich-939	75	11	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	75	12	847	847	NUM
biomedich-939	75	13	methoxyl	methoxyl	NOUN
biomedich-939	75	14	group	group	NOUN
biomedich-939	75	15	.	.	PUNCT
biomedich-939	76	1	although	although	SCONJ
biomedich-939	76	2	it	it	PRON
biomedich-939	76	3	also	also	ADV
biomedich-939	76	4	inductively	inductively	ADV
biomedich-939	76	5	withdraws	withdraw	VERB
biomedich-939	76	6	(	(	PUNCT
biomedich-939	76	7	–	–	PUNCT
biomedich-939	76	8	i	i	NOUN
biomedich-939	76	9	)	)	PUNCT
biomedich-939	76	10	electrons	electron	NOUN
biomedich-939	76	11	,	,	PUNCT
biomedich-939	76	12	which	which	PRON
biomedich-939	76	13	is	be	AUX
biomedich-939	76	14	a	a	DET
biomedich-939	76	15	deactivating	deactivate	VERB
biomedich-939	76	16	effect	effect	NOUN
biomedich-939	76	17	,	,	PUNCT
biomedich-939	76	18	the	the	DET
biomedich-939	76	19	resonance	resonance	NOUN
biomedich-939	76	20	(	(	PUNCT
biomedich-939	76	21	or	or	CCONJ
biomedich-939	76	22	mesomeric	mesomeric	NOUN
biomedich-939	76	23	)	)	PUNCT
biomedich-939	76	24	effect	effect	NOUN
biomedich-939	76	25	is	be	AUX
biomedich-939	76	26	stronger	strong	ADJ
biomedich-939	76	27	,	,	PUNCT
biomedich-939	76	28	hence	hence	ADV
biomedich-939	76	29	an	an	DET
biomedich-939	76	30	even	even	ADV
biomedich-939	76	31	electron	electron	NOUN
biomedich-939	76	32	distribution	distribution	NOUN
biomedich-939	76	33	which	which	PRON
biomedich-939	76	34	accounts	account	VERB
biomedich-939	76	35	for	for	ADP
biomedich-939	76	36	the	the	DET
biomedich-939	76	37	reduced	reduced	ADJ
biomedich-939	76	38	electronegativity	electronegativity	NOUN
biomedich-939	76	39	.	.	PUNCT
biomedich-939	77	1	the	the	DET
biomedich-939	77	2	information	information	NOUN
biomedich-939	77	3	about	about	ADP
biomedich-939	77	4	the	the	DET
biomedich-939	77	5	physico	physico	NOUN
biomedich-939	77	6	-	-	PUNCT
biomedich-939	77	7	chemical	chemical	NOUN
biomedich-939	77	8	properties	property	NOUN
biomedich-939	77	9	and	and	CCONJ
biomedich-939	77	10	chemical	chemical	NOUN
biomedich-939	77	11	reactivity	reactivity	NOUN
biomedich-939	77	12	phenomena	phenomenon	NOUN
biomedich-939	77	13	of	of	ADP
biomedich-939	77	14	a	a	DET
biomedich-939	77	15	molecule	molecule	NOUN
biomedich-939	77	16	can	can	AUX
biomedich-939	77	17	also	also	ADV
biomedich-939	77	18	be	be	AUX
biomedich-939	77	19	revealed	reveal	VERB
biomedich-939	77	20	by	by	ADP
biomedich-939	77	21	a	a	DET
biomedich-939	77	22	measure	measure	NOUN
biomedich-939	77	23	of	of	ADP
biomedich-939	77	24	the	the	DET
biomedich-939	77	25	stabilization	stabilization	NOUN
biomedich-939	77	26	energy	energy	NOUN
biomedich-939	77	27	of	of	ADP
biomedich-939	77	28	the	the	DET
biomedich-939	77	29	molecule	molecule	NOUN
biomedich-939	77	30	when	when	SCONJ
biomedich-939	77	31	it	it	PRON
biomedich-939	77	32	accepts	accept	VERB
biomedich-939	77	33	an	an	DET
biomedich-939	77	34	arbitrary	arbitrary	ADJ
biomedich-939	77	35	number	number	NOUN
biomedich-939	77	36	of	of	ADP
biomedich-939	77	37	electrons	electron	NOUN
biomedich-939	77	38	approaching	approach	VERB
biomedich-939	77	39	from	from	ADP
biomedich-939	77	40	the	the	DET
biomedich-939	77	41	surroundings	surrounding	NOUN
biomedich-939	77	42	.	.	PUNCT
biomedich-939	78	1	this	this	DET
biomedich-939	78	2	concept	concept	NOUN
biomedich-939	78	3	is	be	AUX
biomedich-939	78	4	termed	term	VERB
biomedich-939	78	5	electrophilicity	electrophilicity	NOUN
biomedich-939	78	6	index	index	NOUN
biomedich-939	78	7	(	(	PUNCT
biomedich-939	78	8	ω	ω	NOUN
biomedich-939	78	9	)	)	PUNCT
biomedich-939	78	10	(	(	PUNCT
biomedich-939	78	11	tandon	tandon	PROPN
biomedich-939	78	12	et	et	PROPN
biomedich-939	78	13	al	al	PROPN
biomedich-939	78	14	.	.	PROPN
biomedich-939	78	15	,	,	PUNCT
biomedich-939	78	16	2020	2020	NUM
biomedich-939	78	17	)	)	PUNCT
biomedich-939	78	18	.	.	PUNCT
biomedich-939	79	1	this	this	DET
biomedich-939	79	2	approach	approach	NOUN
biomedich-939	79	3	can	can	AUX
biomedich-939	79	4	be	be	AUX
biomedich-939	79	5	explained	explain	VERB
biomedich-939	79	6	in	in	ADP
biomedich-939	79	7	two	two	NUM
biomedich-939	79	8	ways	way	NOUN
biomedich-939	79	9	;	;	PUNCT
biomedich-939	79	10	the	the	DET
biomedich-939	79	11	global	global	ADJ
biomedich-939	79	12	electro	electro	NOUN
biomedich-939	79	13	-	-	PUNCT
biomedich-939	79	14	accepting	accept	VERB
biomedich-939	79	15	power	power	NOUN
biomedich-939	79	16	ω+	ω+	NOUN
biomedich-939	79	17	and	and	CCONJ
biomedich-939	79	18	electro	electro	NOUN
biomedich-939	79	19	-	-	PUNCT
biomedich-939	79	20	donating	donate	VERB
biomedich-939	79	21	power	power	NOUN
biomedich-939	79	22	ω−.	ω−.	PROPN
biomedich-939	79	23	the	the	DET
biomedich-939	79	24	electrondonating	electrondonating	NOUN
biomedich-939	79	25	power	power	NOUN
biomedich-939	79	26	is	be	AUX
biomedich-939	79	27	a	a	DET
biomedich-939	79	28	measure	measure	NOUN
biomedich-939	79	29	of	of	ADP
biomedich-939	79	30	the	the	DET
biomedich-939	79	31	nucleophilicity	nucleophilicity	NOUN
biomedich-939	79	32	of	of	ADP
biomedich-939	79	33	the	the	DET
biomedich-939	79	34	system	system	NOUN
biomedich-939	79	35	and	and	CCONJ
biomedich-939	79	36	it	it	PRON
biomedich-939	79	37	involves	involve	VERB
biomedich-939	79	38	the	the	DET
biomedich-939	79	39	destabilizing	destabilizing	ADJ
biomedich-939	79	40	change	change	NOUN
biomedich-939	79	41	in	in	ADP
biomedich-939	79	42	energy	energy	NOUN
biomedich-939	79	43	required	require	VERB
biomedich-939	79	44	by	by	ADP
biomedich-939	79	45	a	a	DET
biomedich-939	79	46	system	system	NOUN
biomedich-939	79	47	to	to	PART
biomedich-939	79	48	attain	attain	VERB
biomedich-939	79	49	zero	zero	NUM
biomedich-939	79	50	chemical	chemical	NOUN
biomedich-939	79	51	potential	potential	NOUN
biomedich-939	79	52	with	with	ADP
biomedich-939	79	53	accompanied	accompany	VERB
biomedich-939	79	54	a	a	DET
biomedich-939	79	55	decrease	decrease	NOUN
biomedich-939	79	56	in	in	ADP
biomedich-939	79	57	the	the	DET
biomedich-939	79	58	number	number	NOUN
biomedich-939	79	59	of	of	ADP
biomedich-939	79	60	electrons	electron	NOUN
biomedich-939	79	61	of	of	ADP
biomedich-939	79	62	the	the	DET
biomedich-939	79	63	system	system	NOUN
biomedich-939	79	64	.	.	PUNCT
biomedich-939	80	1	on	on	ADP
biomedich-939	80	2	the	the	DET
biomedich-939	80	3	other	other	ADJ
biomedich-939	80	4	hand	hand	NOUN
biomedich-939	80	5	,	,	PUNCT
biomedich-939	80	6	the	the	DET
biomedich-939	80	7	electronaccepting	electronaccepte	VERB
biomedich-939	80	8	power	power	NOUN
biomedich-939	80	9	ω+	ω+	NUM
biomedich-939	80	10	of	of	ADP
biomedich-939	80	11	a	a	DET
biomedich-939	80	12	molecular	molecular	ADJ
biomedich-939	80	13	system	system	NOUN
biomedich-939	80	14	,	,	PUNCT
biomedich-939	80	15	can	can	AUX
biomedich-939	80	16	be	be	AUX
biomedich-939	80	17	defined	define	VERB
biomedich-939	80	18	base	base	NOUN
biomedich-939	80	19	on	on	ADP
biomedich-939	80	20	the	the	DET
biomedich-939	80	21	stabilizing	stabilize	VERB
biomedich-939	80	22	energy	energy	NOUN
biomedich-939	80	23	change	change	NOUN
biomedich-939	80	24	of	of	ADP
biomedich-939	80	25	such	such	ADJ
biomedich-939	80	26	system	system	NOUN
biomedich-939	80	27	when	when	SCONJ
biomedich-939	80	28	it	it	PRON
biomedich-939	80	29	is	be	AUX
biomedich-939	80	30	saturated	saturate	VERB
biomedich-939	80	31	with	with	ADP
biomedich-939	80	32	maximum	maximum	ADJ
biomedich-939	80	33	number	number	NOUN
biomedich-939	80	34	of	of	ADP
biomedich-939	80	35	electrons	electron	NOUN
biomedich-939	80	36	(	(	PUNCT
biomedich-939	80	37	gazquez	gazquez	NOUN
biomedich-939	80	38	et	et	PROPN
biomedich-939	80	39	al	al	PROPN
biomedich-939	80	40	.	.	PROPN
biomedich-939	80	41	,	,	PUNCT
biomedich-939	80	42	2014	2014	NUM
biomedich-939	80	43	)	)	PUNCT
biomedich-939	80	44	.	.	PUNCT
biomedich-939	81	1	the	the	DET
biomedich-939	81	2	net	net	ADJ
biomedich-939	81	3	electrophilicty	electrophilicty	ADV
biomedich-939	81	4	δω±	δω±	NOUN
biomedich-939	81	5	,	,	PUNCT
biomedich-939	81	6	describes	describe	NOUN
biomedich-939	81	7	of	of	ADP
biomedich-939	81	8	intermolecular	intermolecular	ADJ
biomedich-939	81	9	reactivity	reactivity	NOUN
biomedich-939	81	10	(	(	PUNCT
biomedich-939	81	11	frau	frau	ADJ
biomedich-939	81	12	&	&	CCONJ
biomedich-939	81	13	glossman	glossman	NOUN
biomedich-939	81	14	-	-	PUNCT
biomedich-939	81	15	mitnik	mitnik	NOUN
biomedich-939	81	16	,	,	PUNCT
biomedich-939	81	17	2017	2017	NUM
biomedich-939	81	18	)	)	PUNCT
biomedich-939	81	19	.	.	PUNCT
biomedich-939	82	1	the	the	DET
biomedich-939	82	2	results	result	NOUN
biomedich-939	82	3	from	from	ADP
biomedich-939	82	4	the	the	DET
biomedich-939	82	5	calculations	calculation	NOUN
biomedich-939	82	6	show	show	VERB
biomedich-939	82	7	that	that	SCONJ
biomedich-939	82	8	the	the	DET
biomedich-939	82	9	2phenoxyuinolines	2phenoxyuinolines	PROPN
biomedich-939	82	10	have	have	VERB
biomedich-939	82	11	an	an	DET
biomedich-939	82	12	average	average	ADJ
biomedich-939	82	13	approximate	approximate	ADJ
biomedich-939	82	14	electron	electron	NOUN
biomedich-939	82	15	donating	donating	NOUN
biomedich-939	82	16	power	power	NOUN
biomedich-939	82	17	,	,	PUNCT
biomedich-939	82	18	ω−	ω−	ADP
biomedich-939	82	19	of	of	ADP
biomedich-939	82	20	9	9	NUM
biomedich-939	82	21	ev	ev	NOUN
biomedich-939	82	22	.	.	PUNCT
biomedich-939	83	1	this	this	DET
biomedich-939	83	2	approximate	approximate	ADJ
biomedich-939	83	3	destabilizing	destabilizing	ADJ
biomedich-939	83	4	energy	energy	NOUN
biomedich-939	83	5	is	be	AUX
biomedich-939	83	6	higher	high	ADJ
biomedich-939	83	7	than	than	ADP
biomedich-939	83	8	the	the	DET
biomedich-939	83	9	average	average	ADJ
biomedich-939	83	10	approximate	approximate	ADJ
biomedich-939	83	11	electron	electron	NOUN
biomedich-939	83	12	accepting	accept	VERB
biomedich-939	83	13	power	power	NOUN
biomedich-939	83	14	,	,	PUNCT
biomedich-939	83	15	ω+	ω+	NOUN
biomedich-939	83	16	of	of	ADP
biomedich-939	83	17	about	about	ADV
biomedich-939	83	18	6	6	NUM
biomedich-939	83	19	ev	ev	VERB
biomedich-939	83	20	except	except	SCONJ
biomedich-939	83	21	for	for	ADP
biomedich-939	83	22	compound	compound	NOUN
biomedich-939	83	23	4	4	NUM
biomedich-939	83	24	which	which	PRON
biomedich-939	83	25	shows	show	VERB
biomedich-939	83	26	a	a	DET
biomedich-939	83	27	very	very	ADV
biomedich-939	83	28	lower	low	ADJ
biomedich-939	83	29	electrophilic	electrophilic	ADJ
biomedich-939	83	30	index	index	NOUN
biomedich-939	83	31	or	or	CCONJ
biomedich-939	83	32	stabilizing	stabilize	VERB
biomedich-939	83	33	energy	energy	NOUN
biomedich-939	83	34	change	change	NOUN
biomedich-939	83	35	accompanying	accompany	VERB
biomedich-939	83	36	electron	electron	NOUN
biomedich-939	83	37	gain	gain	NOUN
biomedich-939	83	38	with	with	ADP
biomedich-939	83	39	ω+	ω+	NUM
biomedich-939	83	40	value	value	NOUN
biomedich-939	83	41	of	of	ADP
biomedich-939	83	42	approximately	approximately	ADV
biomedich-939	83	43	1	1	NUM
biomedich-939	83	44	ev	ev	NOUN
biomedich-939	83	45	.	.	PUNCT
biomedich-939	84	1	this	this	PRON
biomedich-939	84	2	suggests	suggest	VERB
biomedich-939	84	3	that	that	SCONJ
biomedich-939	84	4	the	the	DET
biomedich-939	84	5	2phenoxyuinolines	2phenoxyuinoline	NOUN
biomedich-939	84	6	are	be	AUX
biomedich-939	84	7	strongly	strongly	ADV
biomedich-939	84	8	nucleophilic	nucleophilic	ADJ
biomedich-939	84	9	and	and	CCONJ
biomedich-939	84	10	electrophilic	electrophilic	ADJ
biomedich-939	84	11	but	but	CCONJ
biomedich-939	84	12	more	more	ADV
biomedich-939	84	13	nucleophilic	nucleophilic	ADJ
biomedich-939	84	14	in	in	ADP
biomedich-939	84	15	reactivity	reactivity	NOUN
biomedich-939	84	16	than	than	ADP
biomedich-939	84	17	being	be	AUX
biomedich-939	84	18	electrophilic	electrophilic	ADJ
biomedich-939	84	19	.	.	PUNCT
biomedich-939	85	1	the	the	DET
biomedich-939	85	2	ionization	ionization	NOUN
biomedich-939	85	3	potential	potential	NOUN
biomedich-939	85	4	,	,	PUNCT
biomedich-939	85	5	i	i	PRON
biomedich-939	85	6	and	and	CCONJ
biomedich-939	85	7	electron	electron	NOUN
biomedich-939	85	8	affinity	affinity	NOUN
biomedich-939	85	9	values	value	NOUN
biomedich-939	85	10	also	also	ADV
biomedich-939	85	11	show	show	VERB
biomedich-939	85	12	the	the	DET
biomedich-939	85	13	relative	relative	ADJ
biomedich-939	85	14	tendencies	tendency	NOUN
biomedich-939	85	15	of	of	ADP
biomedich-939	85	16	an	an	DET
biomedich-939	85	17	atoms	atom	NOUN
biomedich-939	85	18	or	or	CCONJ
biomedich-939	85	19	molecule	molecule	NOUN
biomedich-939	85	20	to	to	PART
biomedich-939	85	21	gain	gain	VERB
biomedich-939	85	22	or	or	CCONJ
biomedich-939	85	23	lose	lose	VERB
biomedich-939	85	24	electrons	electron	NOUN
biomedich-939	85	25	in	in	ADP
biomedich-939	85	26	reaction	reaction	NOUN
biomedich-939	85	27	and	and	CCONJ
biomedich-939	85	28	useful	useful	ADJ
biomedich-939	85	29	in	in	ADP
biomedich-939	85	30	the	the	DET
biomedich-939	85	31	calculation	calculation	NOUN
biomedich-939	85	32	of	of	ADP
biomedich-939	85	33	heats	heat	NOUN
biomedich-939	85	34	of	of	ADP
biomedich-939	85	35	various	various	ADJ
biomedich-939	85	36	reactions	reaction	NOUN
biomedich-939	85	37	and	and	CCONJ
biomedich-939	85	38	physical	physical	ADJ
biomedich-939	85	39	changes	change	NOUN
biomedich-939	85	40	(	(	PUNCT
biomedich-939	85	41	smalo	smalo	NOUN
biomedich-939	85	42	et	et	PROPN
biomedich-939	85	43	al	al	PROPN
biomedich-939	85	44	.	.	PROPN
biomedich-939	85	45	,	,	PUNCT
biomedich-939	85	46	2010	2010	NUM
biomedich-939	85	47	)	)	PUNCT
biomedich-939	85	48	.	.	PUNCT
biomedich-939	86	1	reactivity	reactivity	NOUN
biomedich-939	86	2	is	be	AUX
biomedich-939	86	3	inversely	inversely	ADV
biomedich-939	86	4	proportional	proportional	ADJ
biomedich-939	86	5	to	to	ADP
biomedich-939	86	6	ionization	ionization	NOUN
biomedich-939	86	7	potential	potential	NOUN
biomedich-939	86	8	so	so	ADV
biomedich-939	86	9	lower	low	ADJ
biomedich-939	86	10	ionization	ionization	NOUN
biomedich-939	86	11	potential	potential	NOUN
biomedich-939	86	12	would	would	AUX
biomedich-939	86	13	depicts	depict	VERB
biomedich-939	86	14	a	a	DET
biomedich-939	86	15	higher	high	ADJ
biomedich-939	86	16	the	the	DET
biomedich-939	86	17	chemical	chemical	NOUN
biomedich-939	86	18	reactivity	reactivity	NOUN
biomedich-939	86	19	.	.	PUNCT
biomedich-939	87	1	table	table	NOUN
biomedich-939	87	2	1	1	NUM
biomedich-939	87	3	.	.	PUNCT
biomedich-939	88	1	chemical	chemical	ADJ
biomedich-939	88	2	reactivity	reactivity	NOUN
biomedich-939	88	3	descriptors	descriptor	NOUN
biomedich-939	88	4	for	for	ADP
biomedich-939	88	5	the	the	DET
biomedich-939	88	6	synthesised	synthesise	VERB
biomedich-939	88	7	2	2	NUM
biomedich-939	88	8	-	-	PUNCT
biomedich-939	88	9	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	88	10	.	.	PUNCT
biomedich-939	89	1	cpd	cpd	PROPN
biomedich-939	89	2	medium	medium	PROPN
biomedich-939	89	3	el	el	PROPN
biomedich-939	89	4	(	(	PUNCT
biomedich-939	89	5	ev	ev	PROPN
biomedich-939	89	6	)	)	PUNCT
biomedich-939	89	7	eh	eh	INTJ
biomedich-939	89	8	(	(	PUNCT
biomedich-939	89	9	ev	ev	INTJ
biomedich-939	89	10	)	)	PUNCT
biomedich-939	89	11	egap	egap	NOUN
biomedich-939	89	12	(	(	PUNCT
biomedich-939	89	13	ev	ev	PROPN
biomedich-939	89	14	)	)	PUNCT
biomedich-939	89	15	η	η	PROPN
biomedich-939	89	16	s	s	PROPN
biomedich-939	89	17	µ	µ	PROPN
biomedich-939	89	18	ꭓ	ꭓ	PROPN
biomedich-939	89	19	ω	ω	PRON
biomedich-939	89	20	ω¯	ω¯	NUM
biomedich-939	89	21	ω⁺	ω⁺	PROPN
biomedich-939	89	22	∆ω±	∆ω±	PROPN
biomedich-939	89	23	µd	µd	ADP
biomedich-939	89	24	i	i	NOUN
biomedich-939	89	25	1	1	NUM
biomedich-939	89	26	gas	gas	NOUN
biomedich-939	89	27	-2.597	-2.597	NOUN
biomedich-939	89	28	-6.713	-6.713	PUNCT
biomedich-939	89	29	4.116	4.116	NUM
biomedich-939	89	30	2.058	2.058	NUM
biomedich-939	89	31	0.486	0.486	NUM
biomedich-939	89	32	-4.655	-4.655	NOUN
biomedich-939	89	33	4.655	4.655	NUM
biomedich-939	89	34	1.316	1.316	NUM
biomedich-939	89	35	9.345	9.345	NUM
biomedich-939	89	36	6.389	6.389	NUM
biomedich-939	89	37	15.734	15.734	NUM
biomedich-939	89	38	2.597	2.597	NUM
biomedich-939	89	39	6.713	6.713	NUM
biomedich-939	89	40	water	water	NOUN
biomedich-939	89	41	-2.591	-2.591	PUNCT
biomedich-939	89	42	-6.625	-6.625	NUM
biomedich-939	90	1	4.034	4.034	NUM
biomedich-939	90	2	2.017	2.017	NUM
biomedich-939	90	3	0.496	0.496	NUM
biomedich-939	90	4	-4.608	-4.608	NOUN
biomedich-939	90	5	4.608	4.608	NUM
biomedich-939	90	6	1.316	1.316	NUM
biomedich-939	90	7	9.257	9.257	NUM
biomedich-939	90	8	6.424	6.424	NUM
biomedich-939	90	9	15.680	15.680	NUM
biomedich-939	90	10	2.591	2.591	NUM
biomedich-939	90	11	6.625	6.625	NUM
biomedich-939	90	12	ethanol	ethanol	NOUN
biomedich-939	90	13	-2.565	-2.565	NOUN
biomedich-939	90	14	-6.614	-6.614	PUNCT
biomedich-939	90	15	4.049	4.049	NUM
biomedich-939	90	16	2.025	2.025	NUM
biomedich-939	90	17	0.494	0.494	NUM
biomedich-939	90	18	-4.590	-4.590	NUM
biomedich-939	90	19	4.590	4.590	NUM
biomedich-939	90	20	1.301	1.301	NUM
biomedich-939	90	21	9.215	9.215	NUM
biomedich-939	90	22	6.321	6.321	NUM
biomedich-939	90	23	15.536	15.536	NUM
biomedich-939	90	24	2.565	2.565	NUM
biomedich-939	90	25	6.614	6.614	NUM
biomedich-939	90	26	2	2	NUM
biomedich-939	90	27	gas	gas	NOUN
biomedich-939	90	28	-2.584	-2.584	X
biomedich-939	90	29	-6.769	-6.769	NOUN
biomedich-939	91	1	4.185	4.185	NUM
biomedich-939	91	2	2.093	2.093	NUM
biomedich-939	91	3	0.478	0.478	NUM
biomedich-939	91	4	-4.677	-4.677	NUM
biomedich-939	91	5	4.677	4.677	NUM
biomedich-939	91	6	1.306	1.306	NUM
biomedich-939	91	7	9.382	9.382	NUM
biomedich-939	91	8	6.298	6.298	NUM
biomedich-939	91	9	15.680	15.680	NUM
biomedich-939	91	10	2.584	2.584	NUM
biomedich-939	91	11	6.769	6.769	NUM
biomedich-939	91	12	water	water	NOUN
biomedich-939	91	13	-2.599	-2.599	PUNCT
biomedich-939	91	14	-6.659	-6.659	NOUN
biomedich-939	91	15	4.060	4.060	NUM
biomedich-939	91	16	2.030	2.030	NUM
biomedich-939	91	17	0.493	0.493	NUM
biomedich-939	91	18	-4.629	-4.629	PUNCT
biomedich-939	91	19	4.629	4.629	NUM
biomedich-939	91	20	1.319	1.319	NUM
biomedich-939	91	21	9.298	9.298	NUM
biomedich-939	91	22	6.434	6.434	NUM
biomedich-939	91	23	15.732	15.732	NUM
biomedich-939	91	24	2.599	2.599	NUM
biomedich-939	91	25	6.659	6.659	NUM
biomedich-939	91	26	ethanol	ethanol	NOUN
biomedich-939	91	27	-2.573	-2.573	PUNCT
biomedich-939	91	28	-6.651	-6.651	NOUN
biomedich-939	91	29	4.078	4.078	NUM
biomedich-939	91	30	2.039	2.039	NUM
biomedich-939	91	31	0.490	0.490	NUM
biomedich-939	91	32	-4.612	-4.612	NOUN
biomedich-939	91	33	4.612	4.612	NUM
biomedich-939	91	34	1.304	1.304	NUM
biomedich-939	91	35	9.259	9.259	NUM
biomedich-939	91	36	6.330	6.330	NUM
biomedich-939	91	37	15.589	15.589	NUM
biomedich-939	91	38	2.573	2.573	NUM
biomedich-939	91	39	6.651	6.651	NUM
biomedich-939	91	40	3	3	NUM
biomedich-939	91	41	gas	gas	NOUN
biomedich-939	91	42	-2.750	-2.750	NOUN
biomedich-939	91	43	-6.678	-6.678	ADP
biomedich-939	91	44	3.928	3.928	NUM
biomedich-939	91	45	1.964	1.964	NUM
biomedich-939	91	46	0.509	0.509	NUM
biomedich-939	91	47	-4.714	-4.714	NUM
biomedich-939	91	48	4.714	4.714	NUM
biomedich-939	91	49	1.414	1.414	NUM
biomedich-939	91	50	9.507	9.507	NUM
biomedich-939	91	51	7.092	7.092	NUM
biomedich-939	91	52	16.598	16.598	NUM
biomedich-939	91	53	2.750	2.750	NUM
biomedich-939	91	54	6.678	6.678	NUM
biomedich-939	91	55	water	water	NOUN
biomedich-939	91	56	-2.670	-2.670	PRON
biomedich-939	91	57	-6.577	-6.577	PUNCT
biomedich-939	91	58	3.907	3.907	NUM
biomedich-939	91	59	1.954	1.954	NUM
biomedich-939	91	60	0.512	0.512	NUM
biomedich-939	91	61	-4.624	-4.624	NUM
biomedich-939	91	62	4.624	4.624	NUM
biomedich-939	91	63	1.368	1.368	NUM
biomedich-939	91	64	9.313	9.313	NUM
biomedich-939	91	65	6.808	6.808	NUM
biomedich-939	91	66	16.120	16.120	NUM
biomedich-939	91	67	2.670	2.670	NUM
biomedich-939	91	68	6.577	6.577	NUM
biomedich-939	91	69	ethanol	ethanol	NOUN
biomedich-939	91	70	-2.649	-2.649	NOUN
biomedich-939	91	71	-6.554	-6.554	PUNCT
biomedich-939	91	72	3.905	3.905	NUM
biomedich-939	91	73	1.953	1.953	NUM
biomedich-939	91	74	0.512	0.512	NUM
biomedich-939	91	75	-4.602	-4.602	NUM
biomedich-939	91	76	4.602	4.602	NUM
biomedich-939	91	77	1.356	1.356	NUM
biomedich-939	91	78	9.265	9.265	NUM
biomedich-939	91	79	6.731	6.731	NUM
biomedich-939	91	80	15.996	15.996	NUM
biomedich-939	91	81	2.649	2.649	NUM
biomedich-939	91	82	6.554	6.554	NUM
biomedich-939	91	83	4	4	NUM
biomedich-939	91	84	gas	gas	NOUN
biomedich-939	91	85	-2.536	-2.536	NOUN
biomedich-939	91	86	-6.076	-6.076	VERB
biomedich-939	91	87	3.54	3.54	NUM
biomedich-939	91	88	1.77	1.77	NUM
biomedich-939	91	89	0.565	0.565	NUM
biomedich-939	91	90	-4.306	-4.306	ADP
biomedich-939	91	91	4.306	4.306	NUM
biomedich-939	91	92	1.309	1.309	NUM
biomedich-939	91	93	8.695	8.695	NUM
biomedich-939	91	94	6.612	6.612	NUM
biomedich-939	91	95	15.306	15.306	NUM
biomedich-939	91	96	2.536	2.536	NUM
biomedich-939	91	97	6.076	6.076	NUM
biomedich-939	91	98	water	water	NOUN
biomedich-939	91	99	-2.416	-2.416	PUNCT
biomedich-939	91	100	-6.628	-6.628	PUNCT
biomedich-939	92	1	4.212	4.212	NUM
biomedich-939	92	2	2.106	2.106	NUM
biomedich-939	92	3	0.475	0.475	NUM
biomedich-939	92	4	-4.522	-4.522	NUM
biomedich-939	92	5	4.522	4.522	NUM
biomedich-939	92	6	1.214	1.214	NUM
biomedich-939	92	7	9.055	9.055	NUM
biomedich-939	92	8	5.714	5.714	NUM
biomedich-939	92	9	14.770	14.770	NUM
biomedich-939	92	10	2.416	2.416	NUM
biomedich-939	92	11	6.628	6.628	NUM
biomedich-939	92	12	ethanol	ethanol	NOUN
biomedich-939	92	13	-2.388	-2.388	PUNCT
biomedich-939	92	14	-6.599	-6.599	PUNCT
biomedich-939	92	15	4.211	4.211	NUM
biomedich-939	92	16	2.1055	2.1055	NUM
biomedich-939	92	17	0.475	0.475	NUM
biomedich-939	92	18	-4.494	-4.494	NUM
biomedich-939	92	19	4.494	4.494	NUM
biomedich-939	92	20	1.199	1.199	NUM
biomedich-939	92	21	8.996	8.996	NUM
biomedich-939	92	22	5.623	5.623	NUM
biomedich-939	92	23	14.619	14.619	NUM
biomedich-939	92	24	2.388	2.388	NUM
biomedich-939	92	25	6.599	6.599	NUM
biomedich-939	92	26	5	5	NUM
biomedich-939	92	27	gas	gas	NOUN
biomedich-939	92	28	-2.373	-2.373	ADP
biomedich-939	92	29	-6.499	-6.499	PROPN
biomedich-939	92	30	4.126	4.126	NUM
biomedich-939	92	31	2.063	2.063	NUM
biomedich-939	92	32	0.485	0.485	NUM
biomedich-939	92	33	-4.436	-4.436	NUM
biomedich-939	92	34	4.436	4.436	NUM
biomedich-939	92	35	1.192	1.192	NUM
biomedich-939	92	36	8.884	8.884	NUM
biomedich-939	92	37	5.618	5.618	NUM
biomedich-939	92	38	14.502	14.502	NUM
biomedich-939	92	39	2.373	2.373	NUM
biomedich-939	92	40	6.499	6.499	NUM
biomedich-939	92	41	water	water	NOUN
biomedich-939	92	42	-2.564	-2.564	NUM
biomedich-939	92	43	-6.514	-6.514	NOUN
biomedich-939	92	44	3.950	3.950	NUM
biomedich-939	92	45	1.975	1.975	NUM
biomedich-939	92	46	0.506	0.506	NUM
biomedich-939	92	47	-4.539	-4.539	PROPN
biomedich-939	92	48	4.539	4.539	NUM
biomedich-939	92	49	1.304	1.304	NUM
biomedich-939	92	50	9.122	9.122	NUM
biomedich-939	92	51	6.386	6.386	NUM
biomedich-939	92	52	15.508	15.508	NUM
biomedich-939	92	53	2.564	2.564	NUM
biomedich-939	92	54	6.514	6.514	NUM
biomedich-939	92	55	ethanol	ethanol	NOUN
biomedich-939	92	56	-2.528	-2.528	NOUN
biomedich-939	92	57	-6.496	-6.496	PUNCT
biomedich-939	92	58	3.968	3.968	NUM
biomedich-939	92	59	1.984	1.984	NUM
biomedich-939	92	60	0.504	0.504	NUM
biomedich-939	92	61	-4.512	-4.512	NUM
biomedich-939	92	62	4.512	4.512	NUM
biomedich-939	92	63	1.283	1.283	NUM
biomedich-939	92	64	9.061	9.061	NUM
biomedich-939	92	65	6.245	6.245	NUM
biomedich-939	92	66	15.306	15.306	NUM
biomedich-939	92	67	2.528	2.528	NUM
biomedich-939	92	68	6.496	6.496	NUM
biomedich-939	92	69	6	6	NUM
biomedich-939	92	70	gas	gas	NOUN
biomedich-939	92	71	-2.633	-2.633	PUNCT
biomedich-939	92	72	-6.801	-6.801	PUNCT
biomedich-939	92	73	4.168	4.168	NUM
biomedich-939	92	74	2.084	2.084	NUM
biomedich-939	92	75	0.480	0.480	NUM
biomedich-939	92	76	-4.717	-4.717	PUNCT
biomedich-939	92	77	4.717	4.717	NUM
biomedich-939	92	78	1.335	1.335	NUM
biomedich-939	92	79	9.470	9.470	NUM
biomedich-939	92	80	6.481	6.481	NUM
biomedich-939	92	81	15.951	15.951	NUM
biomedich-939	92	82	2.633	2.633	NUM
biomedich-939	92	83	6.801	6.801	NUM
biomedich-939	92	84	water	water	NOUN
biomedich-939	92	85	-2.642	-2.642	VERB
biomedich-939	92	86	-6.72	-6.72	PRON
biomedich-939	92	87	4.078	4.078	NUM
biomedich-939	92	88	2.039	2.039	NUM
biomedich-939	92	89	0.490	0.490	NUM
biomedich-939	92	90	-4.681	-4.681	NUM
biomedich-939	92	91	4.681	4.681	NUM
biomedich-939	92	92	1.343291	1.343291	NUM
biomedich-939	92	93	9.406582	9.406582	NUM
biomedich-939	92	94	6.575077	6.575077	NUM
biomedich-939	92	95	15.98166	15.98166	NUM
biomedich-939	92	96	2.642	2.642	NUM
biomedich-939	92	97	6.72	6.72	NUM
biomedich-939	92	98	ethanol	ethanol	NOUN
biomedich-939	92	99	-2.615	-2.615	NOUN
biomedich-939	92	100	-6.712	-6.712	NOUN
biomedich-939	92	101	4.097	4.097	NUM
biomedich-939	92	102	2.049	2.049	NUM
biomedich-939	92	103	0.488	0.488	NUM
biomedich-939	92	104	-4.664	-4.664	PUNCT
biomedich-939	92	105	4.664	4.664	NUM
biomedich-939	92	106	1.327	1.327	NUM
biomedich-939	92	107	9.366	9.366	NUM
biomedich-939	92	108	6.465	6.465	NUM
biomedich-939	92	109	15.831	15.831	NUM
biomedich-939	92	110	2.615	2.615	NUM
biomedich-939	92	111	6.712	6.712	NUM
biomedich-939	92	112	7	7	NUM
biomedich-939	92	113	gas	gas	NOUN
biomedich-939	92	114	-2.694	-2.694	NOUN
biomedich-939	92	115	-6.140	-6.140	NOUN
biomedich-939	92	116	3.446	3.446	NUM
biomedich-939	92	117	1.723	1.723	NUM
biomedich-939	92	118	0.580	0.580	NUM
biomedich-939	92	119	-4.417	-4.417	PUNCT
biomedich-939	92	120	4.417	4.417	NUM
biomedich-939	92	121	1.415	1.415	NUM
biomedich-939	92	122	8.971	8.971	NUM
biomedich-939	92	123	7.337	7.337	NUM
biomedich-939	92	124	16.308	16.308	NUM
biomedich-939	92	125	2.694	2.694	NUM
biomedich-939	92	126	6.140	6.140	NUM
biomedich-939	92	127	water	water	NOUN
biomedich-939	92	128	-2.610	-2.610	PUNCT
biomedich-939	92	129	-5.991	-5.991	PUNCT
biomedich-939	92	130	3.381	3.381	NUM
biomedich-939	92	131	1.691	1.691	NUM
biomedich-939	92	132	0.592	0.592	NUM
biomedich-939	92	133	-4.301	-4.301	NUM
biomedich-939	92	134	4.301	4.301	NUM
biomedich-939	92	135	1.368	1.368	NUM
biomedich-939	92	136	8.726	8.726	NUM
biomedich-939	92	137	7.062	7.062	NUM
biomedich-939	92	138	15.788	15.788	NUM
biomedich-939	92	139	2.610	2.610	NUM
biomedich-939	92	140	5.991	5.991	NUM
biomedich-939	92	141	ethanol	ethanol	NOUN
biomedich-939	92	142	-2.599	-2.599	PUNCT
biomedich-939	92	143	-5.988	-5.988	NUM
biomedich-939	92	144	3.389	3.389	NUM
biomedich-939	92	145	1.695	1.695	NUM
biomedich-939	92	146	0.590	0.590	NUM
biomedich-939	92	147	-4.294	-4.294	PUNCT
biomedich-939	92	148	4.294	4.294	NUM
biomedich-939	92	149	1.360	1.360	NUM
biomedich-939	92	150	8.708	8.708	NUM
biomedich-939	92	151	7.009	7.009	NUM
biomedich-939	92	152	15.717	15.717	NUM
biomedich-939	92	153	2.599	2.599	NUM
biomedich-939	92	154	5.988	5.988	NUM
biomedich-939	92	155	8	8	NUM
biomedich-939	92	156	gas	gas	NOUN
biomedich-939	92	157	-2.771	-2.771	NOUN
biomedich-939	92	158	-6.810	-6.810	PUNCT
biomedich-939	92	159	4.039	4.039	NUM
biomedich-939	92	160	2.020	2.020	NUM
biomedich-939	92	161	0.495	0.495	NUM
biomedich-939	92	162	-4.791	-4.791	NUM
biomedich-939	92	163	4.791	4.791	NUM
biomedich-939	92	164	1.420	1.420	NUM
biomedich-939	92	165	9.651	9.651	NUM
biomedich-939	92	166	7.078	7.078	NUM
biomedich-939	92	167	16.729	16.729	NUM
biomedich-939	92	168	2.771	2.771	NUM
biomedich-939	92	169	6.810	6.810	NUM
biomedich-939	92	170	water	water	NOUN
biomedich-939	92	171	-2.696	-2.696	PUNCT
biomedich-939	92	172	-6.680	-6.680	PROPN
biomedich-939	92	173	3.984	3.984	NUM
biomedich-939	92	174	1.992	1.992	NUM
biomedich-939	92	175	0.502	0.502	NUM
biomedich-939	92	176	-4.688	-4.688	NUM
biomedich-939	92	177	4.688	4.688	NUM
biomedich-939	92	178	1.379	1.379	NUM
biomedich-939	92	179	9.438	9.438	NUM
biomedich-939	92	180	6.843	6.843	NUM
biomedich-939	92	181	16.281	16.281	NUM
biomedich-939	92	182	2.696	2.696	NUM
biomedich-939	92	183	6.680	6.680	NUM
biomedich-939	92	184	ethanol	ethanol	NOUN
biomedich-939	92	185	-2.676	-2.676	PUNCT
biomedich-939	92	186	-6.686	-6.686	PUNCT
biomedich-939	92	187	4.010	4.010	NUM
biomedich-939	92	188	2.005	2.005	NUM
biomedich-939	92	189	0.499	0.499	NUM
biomedich-939	92	190	-4.681	-4.681	PUNCT
biomedich-939	92	191	4.681	4.681	NUM
biomedich-939	92	192	1.366	1.366	NUM
biomedich-939	92	193	9.418	9.418	NUM
biomedich-939	92	194	6.749	6.749	NUM
biomedich-939	92	195	16.167	16.167	NUM
biomedich-939	92	196	2.676	2.676	NUM
biomedich-939	92	197	6.686	6.686	NUM
biomedich-939	92	198	a	a	DET
biomedich-939	92	199	units	unit	NOUN
biomedich-939	92	200	for	for	ADP
biomedich-939	92	201	the	the	DET
biomedich-939	92	202	chemical	chemical	NOUN
biomedich-939	92	203	reactivity	reactivity	NOUN
biomedich-939	92	204	descriptors	descriptor	NOUN
biomedich-939	92	205	are	be	AUX
biomedich-939	92	206	in	in	ADP
biomedich-939	92	207	electron	electron	NOUN
biomedich-939	92	208	volts	volt	NOUN
biomedich-939	92	209	(	(	PUNCT
biomedich-939	92	210	ev	ev	PROPN
biomedich-939	92	211	)	)	PUNCT
biomedich-939	92	212	el	el	PROPN
biomedich-939	92	213	:	:	PUNCT
biomedich-939	92	214	lumo	lumo	NOUN
biomedich-939	92	215	energy	energy	NOUN
biomedich-939	92	216	,	,	PUNCT
biomedich-939	92	217	eh	eh	INTJ
biomedich-939	92	218	:	:	PUNCT
biomedich-939	92	219	homo	homo	NOUN
biomedich-939	92	220	energy	energy	NOUN
biomedich-939	92	221	,	,	PUNCT
biomedich-939	92	222	egap	egap	NOUN
biomedich-939	92	223	:	:	PUNCT
biomedich-939	92	224	homo	homo	ADJ
biomedich-939	92	225	-	-	PUNCT
biomedich-939	92	226	lumo	lumo	NOUN
biomedich-939	92	227	energy	energy	NOUN
biomedich-939	92	228	gap	gap	NOUN
biomedich-939	92	229	,	,	PUNCT
biomedich-939	92	230	η	η	NOUN
biomedich-939	92	231	:	:	PUNCT
biomedich-939	92	232	chemical	chemical	ADJ
biomedich-939	92	233	hardness	hardness	NOUN
biomedich-939	92	234	,	,	PUNCT
biomedich-939	92	235	s	s	PART
biomedich-939	92	236	:	:	PUNCT
biomedich-939	92	237	chemical	chemical	NOUN
biomedich-939	92	238	softness	softness	NOUN
biomedich-939	92	239	,	,	PUNCT
biomedich-939	92	240	μ	μ	NOUN
biomedich-939	92	241	:	:	PUNCT
biomedich-939	92	242	chemical	chemical	NOUN
biomedich-939	92	243	potential	potential	NOUN
biomedich-939	92	244	,	,	PUNCT
biomedich-939	92	245	χ	χ	X
biomedich-939	92	246	:	:	PUNCT
biomedich-939	92	247	electronegativity	electronegativity	NOUN
biomedich-939	92	248	,	,	PUNCT
biomedich-939	92	249	ω	ω	NUM
biomedich-939	92	250	:	:	PUNCT
biomedich-939	92	251	electrophilicity	electrophilicity	NOUN
biomedich-939	92	252	index	index	NOUN
biomedich-939	92	253	,	,	PUNCT
biomedich-939	92	254	ω-	ω-	NUM
biomedich-939	92	255	:	:	PUNCT
biomedich-939	92	256	electron	electron	NOUN
biomedich-939	92	257	donating	donating	NOUN
biomedich-939	92	258	power	power	NOUN
biomedich-939	92	259	,	,	PUNCT
biomedich-939	92	260	ω+	ω+	NOUN
biomedich-939	92	261	:	:	PUNCT
biomedich-939	92	262	electron	electron	NOUN
biomedich-939	92	263	accepting	accept	VERB
biomedich-939	92	264	power	power	NOUN
biomedich-939	92	265	,	,	PUNCT
biomedich-939	92	266	δω±	δω±	NOUN
biomedich-939	92	267	:	:	PUNCT
biomedich-939	92	268	net	net	ADJ
biomedich-939	92	269	electrophilicity	electrophilicity	NOUN
biomedich-939	92	270	,	,	PUNCT
biomedich-939	92	271	μd	μd	ADP
biomedich-939	92	272	:	:	PUNCT
biomedich-939	92	273	dipole	dipole	NOUN
biomedich-939	92	274	moment	moment	NOUN
biomedich-939	92	275	,	,	PUNCT
biomedich-939	92	276	i	i	PRON
biomedich-939	92	277	:	:	PUNCT
biomedich-939	92	278	ionization	ionization	NOUN
biomedich-939	92	279	potential	potential	NOUN
biomedich-939	92	280	,	,	PUNCT
biomedich-939	92	281	g	g	NOUN
biomedich-939	92	282	:	:	PUNCT
biomedich-939	92	283	gas	gas	NOUN
biomedich-939	92	284	phase	phase	NOUN
biomedich-939	92	285	,	,	PUNCT
biomedich-939	92	286	w	w	NOUN
biomedich-939	92	287	:	:	PUNCT
biomedich-939	92	288	water	water	NOUN
biomedich-939	92	289	and	and	CCONJ
biomedich-939	92	290	eth	eth	NOUN
biomedich-939	92	291	:	:	PUNCT
biomedich-939	92	292	ethanol	ethanol	NOUN
biomedich-939	92	293	.	.	PUNCT
biomedich-939	93	1	in	in	ADP
biomedich-939	93	2	water	water	NOUN
biomedich-939	93	3	and	and	CCONJ
biomedich-939	93	4	ethanol	ethanol	NOUN
biomedich-939	93	5	,	,	PUNCT
biomedich-939	93	6	the	the	DET
biomedich-939	93	7	ionization	ionization	NOUN
biomedich-939	93	8	potential	potential	ADJ
biomedich-939	93	9	energies	energy	NOUN
biomedich-939	93	10	were	be	AUX
biomedich-939	93	11	lower	low	ADJ
biomedich-939	93	12	when	when	SCONJ
biomedich-939	93	13	compared	compare	VERB
biomedich-939	93	14	to	to	ADP
biomedich-939	93	15	the	the	DET
biomedich-939	93	16	other	other	ADJ
biomedich-939	93	17	gas	gas	NOUN
biomedich-939	93	18	states	state	NOUN
biomedich-939	93	19	calculated	calculate	VERB
biomedich-939	93	20	values	value	NOUN
biomedich-939	93	21	.	.	PUNCT
biomedich-939	94	1	this	this	PRON
biomedich-939	94	2	emphasizes	emphasize	VERB
biomedich-939	94	3	the	the	DET
biomedich-939	94	4	fact	fact	NOUN
biomedich-939	94	5	that	that	SCONJ
biomedich-939	94	6	the	the	DET
biomedich-939	94	7	chemical	chemical	NOUN
biomedich-939	94	8	reactivity	reactivity	NOUN
biomedich-939	94	9	of	of	ADP
biomedich-939	94	10	the	the	DET
biomedich-939	94	11	2	2	NUM
biomedich-939	94	12	-	-	PUNCT
biomedich-939	94	13	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	94	14	is	be	AUX
biomedich-939	94	15	well	well	ADV
biomedich-939	94	16	improved	improve	VERB
biomedich-939	94	17	in	in	ADP
biomedich-939	94	18	water	water	NOUN
biomedich-939	94	19	and	and	CCONJ
biomedich-939	94	20	ethanol	ethanol	NOUN
biomedich-939	94	21	media	medium	NOUN
biomedich-939	94	22	.	.	PUNCT
biomedich-939	95	1	since	since	SCONJ
biomedich-939	95	2	,	,	PUNCT
biomedich-939	95	3	the	the	DET
biomedich-939	95	4	desired	desire	VERB
biomedich-939	95	5	medium	medium	NOUN
biomedich-939	95	6	(	(	PUNCT
biomedich-939	95	7	water	water	NOUN
biomedich-939	95	8	)	)	PUNCT
biomedich-939	95	9	gives	give	VERB
biomedich-939	95	10	favourable	favourable	ADJ
biomedich-939	95	11	intermolecular	intermolecular	ADJ
biomedich-939	95	12	interactions	interaction	NOUN
biomedich-939	95	13	via	via	ADP
biomedich-939	95	14	hydrogen	hydrogen	NOUN
biomedich-939	95	15	bonding	bonding	NOUN
biomedich-939	95	16	,	,	PUNCT
biomedich-939	95	17	therefore	therefore	ADV
biomedich-939	95	18	,	,	PUNCT
biomedich-939	95	19	it	it	PRON
biomedich-939	95	20	reflects	reflect	VERB
biomedich-939	95	21	in	in	ADP
biomedich-939	95	22	lower	low	ADJ
biomedich-939	95	23	ionization	ionization	NOUN
biomedich-939	95	24	potential	potential	NOUN
biomedich-939	95	25	.	.	PUNCT
biomedich-939	96	1	compound	compound	NOUN
biomedich-939	96	2	7	7	NUM
biomedich-939	96	3	has	have	VERB
biomedich-939	96	4	the	the	DET
biomedich-939	96	5	lowest	low	ADJ
biomedich-939	96	6	i	i	PRON
biomedich-939	96	7	value	value	NOUN
biomedich-939	96	8	(	(	PUNCT
biomedich-939	96	9	5.991	5.991	NUM
biomedich-939	96	10	ev	ev	NOUN
biomedich-939	96	11	)	)	PUNCT
biomedich-939	96	12	in	in	ADP
biomedich-939	96	13	water	water	NOUN
biomedich-939	96	14	compared	compare	VERB
biomedich-939	96	15	to	to	ADP
biomedich-939	96	16	other	other	ADJ
biomedich-939	96	17	2phenoxyquinolines	2phenoxyquinolines	PROPN
biomedich-939	96	18	.	.	PROPN
biomedich-939	96	19	848	848	NUM
biomedich-939	96	20	biology	biology	NOUN
biomedich-939	96	21	,	,	PUNCT
biomedich-939	96	22	medicine	medicine	NOUN
biomedich-939	96	23	,	,	PUNCT
biomedich-939	96	24	&	&	CCONJ
biomedich-939	96	25	natural	natural	ADJ
biomedich-939	96	26	product	product	NOUN
biomedich-939	96	27	chemistry	chemistry	NOUN
biomedich-939	96	28	14	14	NUM
biomedich-939	96	29	(	(	PUNCT
biomedich-939	96	30	2	2	NUM
biomedich-939	96	31	)	)	PUNCT
biomedich-939	96	32	,	,	PUNCT
biomedich-939	96	33	2025	2025	NUM
biomedich-939	96	34	:	:	PUNCT
biomedich-939	96	35	843	843	NUM
biomedich-939	96	36	-	-	SYM
biomedich-939	96	37	856	856	NUM
biomedich-939	96	38	figure	figure	NOUN
biomedich-939	96	39	3	3	NUM
biomedich-939	96	40	.	.	NOUN
biomedich-939	96	41	comparison	comparison	NOUN
biomedich-939	96	42	of	of	ADP
biomedich-939	96	43	the	the	DET
biomedich-939	96	44	energy	energy	NOUN
biomedich-939	96	45	gaps	gap	NOUN
biomedich-939	96	46	in	in	ADP
biomedich-939	96	47	gas	gas	NOUN
biomedich-939	96	48	-	-	PUNCT
biomedich-939	96	49	phase	phase	NOUN
biomedich-939	96	50	,	,	PUNCT
biomedich-939	96	51	water	water	NOUN
biomedich-939	96	52	and	and	CCONJ
biomedich-939	96	53	ethanol	ethanol	NOUN
biomedich-939	96	54	.	.	PUNCT
biomedich-939	97	1	atomic	atomic	ADJ
biomedich-939	97	2	charge	charge	NOUN
biomedich-939	97	3	and	and	CCONJ
biomedich-939	97	4	electrostatic	electrostatic	ADJ
biomedich-939	97	5	potential	potential	ADJ
biomedich-939	97	6	molecular	molecular	ADJ
biomedich-939	97	7	electrical	electrical	ADJ
biomedich-939	97	8	charge	charge	NOUN
biomedich-939	97	9	is	be	AUX
biomedich-939	97	10	the	the	DET
biomedich-939	97	11	driving	drive	VERB
biomedich-939	97	12	force	force	NOUN
biomedich-939	97	13	of	of	ADP
biomedich-939	97	14	electrostatic	electrostatic	ADJ
biomedich-939	97	15	interactions	interaction	NOUN
biomedich-939	97	16	characterized	characterize	VERB
biomedich-939	97	17	by	by	ADP
biomedich-939	97	18	electron	electron	NOUN
biomedich-939	97	19	density	density	NOUN
biomedich-939	97	20	playing	play	VERB
biomedich-939	97	21	an	an	DET
biomedich-939	97	22	important	important	ADJ
biomedich-939	97	23	role	role	NOUN
biomedich-939	97	24	in	in	ADP
biomedich-939	97	25	chemical	chemical	ADJ
biomedich-939	97	26	reactions	reaction	NOUN
biomedich-939	97	27	and	and	CCONJ
biomedich-939	97	28	physicochemical	physicochemical	ADJ
biomedich-939	97	29	properties	property	NOUN
biomedich-939	97	30	(	(	PUNCT
biomedich-939	97	31	wang	wang	PROPN
biomedich-939	97	32	&	&	CCONJ
biomedich-939	97	33	truhlar	truhlar	PROPN
biomedich-939	97	34	,	,	PUNCT
biomedich-939	97	35	2014	2014	NUM
biomedich-939	97	36	)	)	PUNCT
biomedich-939	97	37	.	.	PUNCT
biomedich-939	98	1	descriptors	descriptor	NOUN
biomedich-939	98	2	that	that	PRON
biomedich-939	98	3	are	be	AUX
biomedich-939	98	4	charge	charge	NOUN
biomedich-939	98	5	based	base	VERB
biomedich-939	98	6	are	be	AUX
biomedich-939	98	7	often	often	ADV
biomedich-939	98	8	employed	employ	VERB
biomedich-939	98	9	as	as	ADP
biomedich-939	98	10	chemical	chemical	NOUN
biomedich-939	98	11	reactivity	reactivity	NOUN
biomedich-939	98	12	indices	index	NOUN
biomedich-939	98	13	or	or	CCONJ
biomedich-939	98	14	as	as	ADP
biomedich-939	98	15	a	a	DET
biomedich-939	98	16	measure	measure	NOUN
biomedich-939	98	17	of	of	ADP
biomedich-939	98	18	weak	weak	ADJ
biomedich-939	98	19	intermolecular	intermolecular	ADJ
biomedich-939	98	20	interactions	interaction	NOUN
biomedich-939	98	21	.	.	PUNCT
biomedich-939	99	1	the	the	DET
biomedich-939	99	2	partial	partial	ADJ
biomedich-939	99	3	charge	charge	NOUN
biomedich-939	99	4	or	or	CCONJ
biomedich-939	99	5	electron	electron	NOUN
biomedich-939	99	6	density	density	NOUN
biomedich-939	99	7	distribution	distribution	NOUN
biomedich-939	99	8	in	in	ADP
biomedich-939	99	9	a	a	DET
biomedich-939	99	10	molecule	molecule	NOUN
biomedich-939	99	11	is	be	AUX
biomedich-939	99	12	factor	factor	NOUN
biomedich-939	99	13	to	to	ADP
biomedich-939	99	14	determination	determination	NOUN
biomedich-939	99	15	of	of	ADP
biomedich-939	99	16	its	its	PRON
biomedich-939	99	17	reactivity	reactivity	NOUN
biomedich-939	99	18	description	description	NOUN
biomedich-939	99	19	.	.	PUNCT
biomedich-939	100	1	the	the	DET
biomedich-939	100	2	mulliken	mulliken	PROPN
biomedich-939	100	3	atomic	atomic	ADJ
biomedich-939	100	4	charges	charge	NOUN
biomedich-939	100	5	mac	mac	PROPN
biomedich-939	100	6	,	,	PUNCT
biomedich-939	100	7	may	may	AUX
biomedich-939	100	8	be	be	AUX
biomedich-939	100	9	linked	link	VERB
biomedich-939	100	10	to	to	ADP
biomedich-939	100	11	other	other	ADJ
biomedich-939	100	12	chemical	chemical	ADJ
biomedich-939	100	13	parameters	parameter	NOUN
biomedich-939	100	14	such	such	ADJ
biomedich-939	100	15	as	as	ADP
biomedich-939	100	16	dipole	dipole	NOUN
biomedich-939	100	17	moment	moment	NOUN
biomedich-939	100	18	,	,	PUNCT
biomedich-939	100	19	electric	electric	ADJ
biomedich-939	100	20	potentials	potential	NOUN
biomedich-939	100	21	,	,	PUNCT
biomedich-939	100	22	chemical	chemical	NOUN
biomedich-939	100	23	shifts	shift	NOUN
biomedich-939	100	24	,	,	PUNCT
biomedich-939	100	25	electronic	electronic	ADJ
biomedich-939	100	26	structure	structure	NOUN
biomedich-939	100	27	,	,	PUNCT
biomedich-939	100	28	molecular	molecular	ADJ
biomedich-939	100	29	polarizability	polarizability	NOUN
biomedich-939	100	30	and	and	CCONJ
biomedich-939	100	31	others	other	NOUN
biomedich-939	100	32	(	(	PUNCT
biomedich-939	100	33	sumrra	sumrra	VERB
biomedich-939	100	34	et	et	PROPN
biomedich-939	100	35	al	al	PROPN
biomedich-939	100	36	.	.	PROPN
biomedich-939	100	37	,	,	PUNCT
biomedich-939	100	38	2021	2021	NUM
biomedich-939	100	39	)	)	PUNCT
biomedich-939	100	40	.	.	PUNCT
biomedich-939	101	1	a	a	DET
biomedich-939	101	2	uniform	uniform	ADJ
biomedich-939	101	3	distribution	distribution	NOUN
biomedich-939	101	4	of	of	ADP
biomedich-939	101	5	charge	charge	NOUN
biomedich-939	101	6	was	be	AUX
biomedich-939	101	7	found	find	VERB
biomedich-939	101	8	for	for	ADP
biomedich-939	101	9	all	all	DET
biomedich-939	101	10	molecules	molecule	NOUN
biomedich-939	101	11	.	.	PUNCT
biomedich-939	102	1	for	for	ADP
biomedich-939	102	2	3	3	NUM
biomedich-939	102	3	,	,	PUNCT
biomedich-939	102	4	5	5	NUM
biomedich-939	102	5	,	,	PUNCT
biomedich-939	102	6	and	and	CCONJ
biomedich-939	102	7	7	7	NUM
biomedich-939	102	8	,	,	PUNCT
biomedich-939	102	9	which	which	PRON
biomedich-939	102	10	had	have	VERB
biomedich-939	102	11	the	the	DET
biomedich-939	102	12	lowest	low	ADJ
biomedich-939	102	13	energy	energy	NOUN
biomedich-939	102	14	gap	gap	NOUN
biomedich-939	102	15	in	in	ADP
biomedich-939	102	16	aqeous	aqeous	ADJ
biomedich-939	102	17	medium	medium	NOUN
biomedich-939	102	18	and	and	CCONJ
biomedich-939	102	19	were	be	AUX
biomedich-939	102	20	the	the	DET
biomedich-939	102	21	most	most	ADV
biomedich-939	102	22	reactive	reactive	ADJ
biomedich-939	102	23	,	,	PUNCT
biomedich-939	102	24	they	they	PRON
biomedich-939	102	25	had	have	VERB
biomedich-939	102	26	the	the	DET
biomedich-939	102	27	highest	high	ADJ
biomedich-939	102	28	negatively	negatively	ADV
biomedich-939	102	29	charged	charge	VERB
biomedich-939	102	30	atom	atom	NOUN
biomedich-939	102	31	(	(	PUNCT
biomedich-939	102	32	-2.518	-2.518	PROPN
biomedich-939	102	33	a.u	a.u	PROPN
biomedich-939	102	34	,	,	PUNCT
biomedich-939	102	35	−2.609	−2.609	PROPN
biomedich-939	102	36	a.u	a.u	PROPN
biomedich-939	102	37	.	.	PROPN
biomedich-939	102	38	and	and	CCONJ
biomedich-939	102	39	2.021	2.021	NUM
biomedich-939	102	40	a.u	a.u	PROPN
biomedich-939	102	41	.	.	PROPN
biomedich-939	102	42	)	)	PUNCT
biomedich-939	102	43	which	which	PRON
biomedich-939	102	44	is	be	AUX
biomedich-939	102	45	the	the	DET
biomedich-939	102	46	carbon	carbon	NOUN
biomedich-939	102	47	atom	atom	NOUN
biomedich-939	102	48	of	of	ADP
biomedich-939	102	49	the	the	DET
biomedich-939	102	50	imine	imine	NOUN
biomedich-939	102	51	group	group	NOUN
biomedich-939	102	52	at	at	ADP
biomedich-939	102	53	c9	c9	PROPN
biomedich-939	102	54	and	and	CCONJ
biomedich-939	102	55	c14	c14	NOUN
biomedich-939	102	56	positions	position	NOUN
biomedich-939	102	57	attached	attach	VERB
biomedich-939	102	58	to	to	ADP
biomedich-939	102	59	pyridine	pyridine	ADJ
biomedich-939	102	60	nitrogen	nitrogen	NOUN
biomedich-939	102	61	,	,	PUNCT
biomedich-939	102	62	respectively	respectively	ADV
biomedich-939	102	63	(	(	PUNCT
biomedich-939	102	64	figure	figure	NOUN
biomedich-939	102	65	2	2	NUM
biomedich-939	102	66	)	)	PUNCT
biomedich-939	102	67	.	.	PUNCT
biomedich-939	103	1	this	this	DET
biomedich-939	103	2	charge	charge	NOUN
biomedich-939	103	3	is	be	AUX
biomedich-939	103	4	significant	significant	ADJ
biomedich-939	103	5	for	for	ADP
biomedich-939	103	6	the	the	DET
biomedich-939	103	7	bioactivity	bioactivity	NOUN
biomedich-939	103	8	of	of	ADP
biomedich-939	103	9	the	the	DET
biomedich-939	103	10	molecules	molecule	NOUN
biomedich-939	103	11	due	due	ADP
biomedich-939	103	12	to	to	ADP
biomedich-939	103	13	the	the	DET
biomedich-939	103	14	role	role	NOUN
biomedich-939	103	15	the	the	DET
biomedich-939	103	16	f	f	PROPN
biomedich-939	103	17	,	,	PUNCT
biomedich-939	103	18	–	–	PUNCT
biomedich-939	103	19	och3	och3	ADJ
biomedich-939	103	20	groups	group	NOUN
biomedich-939	103	21	play	play	VERB
biomedich-939	103	22	in	in	ADP
biomedich-939	103	23	scavenging	scavenge	VERB
biomedich-939	103	24	radicals	radical	NOUN
biomedich-939	103	25	.	.	PUNCT
biomedich-939	104	1	molecular	molecular	ADJ
biomedich-939	104	2	electrostatic	electrostatic	ADJ
biomedich-939	104	3	potential	potential	ADJ
biomedich-939	104	4	surface	surface	NOUN
biomedich-939	104	5	molecular	molecular	ADJ
biomedich-939	104	6	electrostatic	electrostatic	ADJ
biomedich-939	104	7	potential	potential	NOUN
biomedich-939	104	8	(	(	PUNCT
biomedich-939	104	9	mep	mep	PROPN
biomedich-939	104	10	)	)	PUNCT
biomedich-939	104	11	surfaces	surface	NOUN
biomedich-939	104	12	enhance	enhance	VERB
biomedich-939	104	13	determination	determination	NOUN
biomedich-939	104	14	of	of	ADP
biomedich-939	104	15	the	the	DET
biomedich-939	104	16	reactivity	reactivity	NOUN
biomedich-939	104	17	of	of	ADP
biomedich-939	104	18	chemical	chemical	ADJ
biomedich-939	104	19	compounds	compound	NOUN
biomedich-939	104	20	and	and	CCONJ
biomedich-939	104	21	it	it	PRON
biomedich-939	104	22	is	be	AUX
biomedich-939	104	23	related	relate	VERB
biomedich-939	104	24	to	to	PART
biomedich-939	104	25	electron	electron	VERB
biomedich-939	104	26	density	density	NOUN
biomedich-939	104	27	and	and	CCONJ
biomedich-939	104	28	is	be	AUX
biomedich-939	104	29	a	a	DET
biomedich-939	104	30	useful	useful	ADJ
biomedich-939	104	31	chemical	chemical	NOUN
biomedich-939	104	32	descriptor	descriptor	NOUN
biomedich-939	104	33	that	that	PRON
biomedich-939	104	34	gives	give	VERB
biomedich-939	104	35	information	information	NOUN
biomedich-939	104	36	about	about	ADP
biomedich-939	104	37	sites	site	NOUN
biomedich-939	104	38	of	of	ADP
biomedich-939	104	39	nucleophilic	nucleophilic	ADJ
biomedich-939	104	40	attacks	attack	NOUN
biomedich-939	104	41	,	,	PUNCT
biomedich-939	104	42	electrophilic	electrophilic	ADJ
biomedich-939	104	43	attacks	attack	NOUN
biomedich-939	104	44	and	and	CCONJ
biomedich-939	104	45	hydrogen	hydrogen	NOUN
biomedich-939	104	46	bonding	bonding	NOUN
biomedich-939	104	47	interactions	interaction	NOUN
biomedich-939	104	48	(	(	PUNCT
biomedich-939	104	49	demircioglu	demircioglu	PROPN
biomedich-939	104	50	et	et	NOUN
biomedich-939	104	51	al	al	PROPN
biomedich-939	104	52	.	.	PROPN
biomedich-939	104	53	,	,	PUNCT
biomedich-939	104	54	2019	2019	NUM
biomedich-939	104	55	)	)	PUNCT
biomedich-939	104	56	.	.	PUNCT
biomedich-939	105	1	the	the	DET
biomedich-939	105	2	blue	blue	ADJ
biomedich-939	105	3	region	region	NOUN
biomedich-939	105	4	indicates	indicate	VERB
biomedich-939	105	5	the	the	DET
biomedich-939	105	6	positive	positive	ADJ
biomedich-939	105	7	potential	potential	NOUN
biomedich-939	105	8	of	of	ADP
biomedich-939	105	9	the	the	DET
biomedich-939	105	10	molecule	molecule	NOUN
biomedich-939	105	11	as	as	ADP
biomedich-939	105	12	the	the	DET
biomedich-939	105	13	area	area	NOUN
biomedich-939	105	14	where	where	SCONJ
biomedich-939	105	15	there	there	PRON
biomedich-939	105	16	is	be	VERB
biomedich-939	105	17	proton	proton	NOUN
biomedich-939	105	18	repulsion	repulsion	NOUN
biomedich-939	105	19	(	(	PUNCT
biomedich-939	105	20	that	that	PRON
biomedich-939	105	21	is	be	AUX
biomedich-939	105	22	electrophilic	electrophilic	ADJ
biomedich-939	105	23	attack	attack	NOUN
biomedich-939	105	24	)	)	PUNCT
biomedich-939	105	25	while	while	SCONJ
biomedich-939	105	26	the	the	DET
biomedich-939	105	27	red	red	ADJ
biomedich-939	105	28	region	region	NOUN
biomedich-939	105	29	has	have	VERB
biomedich-939	105	30	negative	negative	ADJ
biomedich-939	105	31	potential	potential	NOUN
biomedich-939	105	32	and	and	CCONJ
biomedich-939	105	33	represents	represent	VERB
biomedich-939	105	34	proton	proton	NOUN
biomedich-939	105	35	attraction	attraction	NOUN
biomedich-939	105	36	(	(	PUNCT
biomedich-939	105	37	nucleophilic	nucleophilic	ADJ
biomedich-939	105	38	attack	attack	NOUN
biomedich-939	105	39	)	)	PUNCT
biomedich-939	105	40	(	(	PUNCT
biomedich-939	105	41	sheikhi	sheikhi	VERB
biomedich-939	105	42	et	et	PROPN
biomedich-939	105	43	al	al	PROPN
biomedich-939	105	44	.	.	PROPN
biomedich-939	105	45	,	,	PUNCT
biomedich-939	105	46	2016	2016	NUM
biomedich-939	105	47	)	)	PUNCT
biomedich-939	105	48	.	.	PUNCT
biomedich-939	106	1	compound	compound	NOUN
biomedich-939	106	2	3	3	NUM
biomedich-939	106	3	compound	compound	NOUN
biomedich-939	106	4	5	5	NUM
biomedich-939	106	5	compound	compound	NOUN
biomedich-939	106	6	7	7	NUM
biomedich-939	106	7	figure	figure	NOUN
biomedich-939	106	8	4	4	NUM
biomedich-939	106	9	.	.	NOUN
biomedich-939	106	10	representative	representative	ADJ
biomedich-939	106	11	optimised	optimise	VERB
biomedich-939	106	12	structures	structure	NOUN
biomedich-939	106	13	of	of	ADP
biomedich-939	106	14	synthesized	synthesize	VERB
biomedich-939	106	15	2	2	NUM
biomedich-939	106	16	-	-	PUNCT
biomedich-939	106	17	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	106	18	.	.	PUNCT
biomedich-939	107	1	compound	compound	NOUN
biomedich-939	107	2	3	3	NUM
biomedich-939	107	3	compound	compound	NOUN
biomedich-939	107	4	5	5	NUM
biomedich-939	107	5	compound	compound	NOUN
biomedich-939	107	6	7	7	NUM
biomedich-939	107	7	figure	figure	NOUN
biomedich-939	107	8	5	5	NUM
biomedich-939	107	9	.	.	PUNCT
biomedich-939	107	10	representative	representative	ADJ
biomedich-939	107	11	atomic	atomic	ADJ
biomedich-939	107	12	charge	charge	NOUN
biomedich-939	107	13	distribution	distribution	NOUN
biomedich-939	107	14	in	in	ADP
biomedich-939	107	15	synthesized	synthesize	VERB
biomedich-939	107	16	2	2	NUM
biomedich-939	107	17	-	-	PUNCT
biomedich-939	107	18	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	107	19	.	.	PUNCT
biomedich-939	108	1	0	0	NUM
biomedich-939	108	2	1	1	NUM
biomedich-939	108	3	2	2	NUM
biomedich-939	108	4	3	3	NUM
biomedich-939	108	5	4	4	NUM
biomedich-939	108	6	5	5	NUM
biomedich-939	108	7	1	1	NUM
biomedich-939	108	8	2	2	NUM
biomedich-939	108	9	3	3	NUM
biomedich-939	108	10	4	4	NUM
biomedich-939	108	11	5	5	NUM
biomedich-939	108	12	6	6	NUM
biomedich-939	108	13	7	7	NUM
biomedich-939	108	14	8	8	NUM
biomedich-939	108	15	eg	eg	NOUN
biomedich-939	108	16	ap	ap	PROPN
biomedich-939	108	17	(	(	PUNCT
biomedich-939	108	18	ev	ev	INTJ
biomedich-939	108	19	)	)	PUNCT
biomedich-939	108	20	gas	gas	NOUN
biomedich-939	108	21	water	water	NOUN
biomedich-939	108	22	ethanol	ethanol	NOUN
biomedich-939	108	23	aina	aina	PROPN
biomedich-939	108	24	et	et	PROPN
biomedich-939	108	25	al	al	PROPN
biomedich-939	108	26	.	.	PROPN
biomedich-939	109	1	–	–	PUNCT
biomedich-939	110	1	dft	dft	PROPN
biomedich-939	110	2	study	study	NOUN
biomedich-939	110	3	and	and	CCONJ
biomedich-939	110	4	admet	admet	PROPN
biomedich-939	110	5	investigation	investigation	NOUN
biomedich-939	110	6	of	of	ADP
biomedich-939	110	7	bioactive	bioactive	ADJ
biomedich-939	110	8	2	2	NUM
biomedich-939	110	9	-	-	PUNCT
biomedich-939	110	10	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	110	11	849	849	NUM
biomedich-939	110	12	all	all	DET
biomedich-939	110	13	the	the	DET
biomedich-939	110	14	2	2	NUM
biomedich-939	110	15	-	-	PUNCT
biomedich-939	110	16	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	110	17	simulated	simulate	VERB
biomedich-939	110	18	in	in	ADP
biomedich-939	110	19	this	this	DET
biomedich-939	110	20	study	study	NOUN
biomedich-939	110	21	have	have	VERB
biomedich-939	110	22	mep	mep	PROPN
biomedich-939	110	23	surfaces	surface	NOUN
biomedich-939	110	24	with	with	ADP
biomedich-939	110	25	an	an	DET
biomedich-939	110	26	overall	overall	ADJ
biomedich-939	110	27	region	region	NOUN
biomedich-939	110	28	of	of	ADP
biomedich-939	110	29	positive	positive	ADJ
biomedich-939	110	30	potential	potential	NOUN
biomedich-939	110	31	around	around	ADP
biomedich-939	110	32	protons	proton	NOUN
biomedich-939	110	33	of	of	ADP
biomedich-939	110	34	the	the	DET
biomedich-939	110	35	c8	c8	PROPN
biomedich-939	110	36	,	,	PUNCT
biomedich-939	110	37	c10	c10	VERB
biomedich-939	110	38	,	,	PUNCT
biomedich-939	110	39	and	and	CCONJ
biomedich-939	110	40	c6	c6	PROPN
biomedich-939	110	41	while	while	SCONJ
biomedich-939	110	42	areas	area	NOUN
biomedich-939	110	43	of	of	ADP
biomedich-939	110	44	negative	negative	ADJ
biomedich-939	110	45	potential	potential	NOUN
biomedich-939	110	46	are	be	AUX
biomedich-939	110	47	around	around	ADP
biomedich-939	110	48	delocalized	delocalize	VERB
biomedich-939	110	49	pielectrons	pielectron	NOUN
biomedich-939	110	50	,	,	PUNCT
biomedich-939	110	51	the	the	DET
biomedich-939	110	52	ether	ether	ADJ
biomedich-939	110	53	oxygen	oxygen	NOUN
biomedich-939	110	54	atoms	atom	NOUN
biomedich-939	110	55	and	and	CCONJ
biomedich-939	110	56	that	that	PRON
biomedich-939	110	57	of	of	ADP
biomedich-939	110	58	the	the	DET
biomedich-939	110	59	carbonyl	carbonyl	NOUN
biomedich-939	110	60	groups	group	NOUN
biomedich-939	110	61	which	which	PRON
biomedich-939	110	62	verifies	verify	VERB
biomedich-939	110	63	the	the	DET
biomedich-939	110	64	necessity	necessity	NOUN
biomedich-939	110	65	of	of	ADP
biomedich-939	110	66	the	the	DET
biomedich-939	110	67	ether	ether	NOUN
biomedich-939	110	68	and	and	CCONJ
biomedich-939	110	69	carbonyl	carbonyl	NOUN
biomedich-939	110	70	groups	group	NOUN
biomedich-939	110	71	for	for	ADP
biomedich-939	110	72	effective	effective	ADJ
biomedich-939	110	73	antioxidant	antioxidant	ADJ
biomedich-939	110	74	properties	property	NOUN
biomedich-939	110	75	of	of	ADP
biomedich-939	110	76	the	the	DET
biomedich-939	110	77	quinolines	quinoline	NOUN
biomedich-939	110	78	.	.	PUNCT
biomedich-939	111	1	the	the	DET
biomedich-939	111	2	carbonyl	carbonyl	NOUN
biomedich-939	111	3	of	of	ADP
biomedich-939	111	4	the	the	DET
biomedich-939	111	5	aldehyde	aldehyde	NOUN
biomedich-939	111	6	and	and	CCONJ
biomedich-939	111	7	acetate	acetate	NOUN
biomedich-939	111	8	groups	group	NOUN
biomedich-939	111	9	of	of	ADP
biomedich-939	111	10	the	the	DET
biomedich-939	111	11	2	2	NUM
biomedich-939	111	12	-	-	PUNCT
biomedich-939	111	13	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	111	14	contributes	contribute	VERB
biomedich-939	111	15	effectively	effectively	ADV
biomedich-939	111	16	to	to	ADP
biomedich-939	111	17	the	the	DET
biomedich-939	111	18	reactive	reactive	ADJ
biomedich-939	111	19	oxygen	oxygen	NOUN
biomedich-939	111	20	and	and	CCONJ
biomedich-939	111	21	hydrogen	hydrogen	NOUN
biomedich-939	111	22	species	specie	NOUN
biomedich-939	111	23	’	'	PUNCT
biomedich-939	111	24	scavenging	scavenge	VERB
biomedich-939	111	25	abilities	ability	NOUN
biomedich-939	111	26	of	of	ADP
biomedich-939	111	27	the	the	DET
biomedich-939	111	28	compounds	compound	NOUN
biomedich-939	111	29	as	as	SCONJ
biomedich-939	111	30	they	they	PRON
biomedich-939	111	31	offer	offer	VERB
biomedich-939	111	32	stability	stability	NOUN
biomedich-939	111	33	.	.	PUNCT
biomedich-939	112	1	it	it	PRON
biomedich-939	112	2	is	be	AUX
biomedich-939	112	3	a	a	DET
biomedich-939	112	4	known	known	ADJ
biomedich-939	112	5	phenomenon	phenomenon	NOUN
biomedich-939	112	6	that	that	SCONJ
biomedich-939	112	7	the	the	DET
biomedich-939	112	8	regions	region	NOUN
biomedich-939	112	9	of	of	ADP
biomedich-939	112	10	negative	negative	ADJ
biomedich-939	112	11	potential	potential	NOUN
biomedich-939	112	12	in	in	ADP
biomedich-939	112	13	the	the	DET
biomedich-939	112	14	2	2	NUM
biomedich-939	112	15	-	-	PUNCT
biomedich-939	112	16	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	112	17	compounds	compound	NOUN
biomedich-939	112	18	will	will	AUX
biomedich-939	112	19	have	have	AUX
biomedich-939	112	20	an	an	DET
biomedich-939	112	21	affinity	affinity	NOUN
biomedich-939	112	22	for	for	ADP
biomedich-939	112	23	the	the	DET
biomedich-939	112	24	positively	positively	ADV
biomedich-939	112	25	charged	charge	VERB
biomedich-939	112	26	side	side	NOUN
biomedich-939	112	27	groups	group	NOUN
biomedich-939	112	28	of	of	ADP
biomedich-939	112	29	amino	amino	ADJ
biomedich-939	112	30	acids	acid	NOUN
biomedich-939	112	31	(	(	PUNCT
biomedich-939	112	32	arginine	arginine	NOUN
biomedich-939	112	33	,	,	PUNCT
biomedich-939	112	34	histidine	histidine	NOUN
biomedich-939	112	35	and	and	CCONJ
biomedich-939	112	36	lysine	lysine	NOUN
biomedich-939	112	37	)	)	PUNCT
biomedich-939	112	38	and	and	CCONJ
biomedich-939	112	39	regions	region	NOUN
biomedich-939	112	40	of	of	ADP
biomedich-939	112	41	positive	positive	ADJ
biomedich-939	112	42	potential	potential	NOUN
biomedich-939	112	43	of	of	ADP
biomedich-939	112	44	the	the	PRON
biomedich-939	112	45	will	will	AUX
biomedich-939	112	46	bind	bind	VERB
biomedich-939	112	47	to	to	ADP
biomedich-939	112	48	the	the	DET
biomedich-939	112	49	negatively	negatively	ADV
biomedich-939	112	50	charged	charge	VERB
biomedich-939	112	51	side	side	NOUN
biomedich-939	112	52	groups	group	NOUN
biomedich-939	112	53	of	of	ADP
biomedich-939	112	54	amino	amino	ADJ
biomedich-939	112	55	acids	acid	NOUN
biomedich-939	112	56	such	such	ADJ
biomedich-939	112	57	as	as	ADP
biomedich-939	112	58	glutamic	glutamic	ADJ
biomedich-939	112	59	acid	acid	NOUN
biomedich-939	112	60	and	and	CCONJ
biomedich-939	112	61	aspartic	aspartic	ADJ
biomedich-939	112	62	acid	acid	NOUN
biomedich-939	112	63	(	(	PUNCT
biomedich-939	112	64	shinde	shinde	NOUN
biomedich-939	112	65	,	,	PUNCT
biomedich-939	112	66	2021	2021	NUM
biomedich-939	112	67	)	)	PUNCT
biomedich-939	112	68	.	.	PUNCT
biomedich-939	113	1	uv	uv	NOUN
biomedich-939	113	2	–	–	PUNCT
biomedich-939	113	3	vis	vis	X
biomedich-939	113	4	spectroscopy	spectroscopy	NOUN
biomedich-939	113	5	uv	uv	NOUN
biomedich-939	113	6	–	–	NOUN
biomedich-939	113	7	visible	visible	ADJ
biomedich-939	113	8	spectroscopy	spectroscopy	NOUN
biomedich-939	113	9	has	have	AUX
biomedich-939	113	10	emerged	emerge	VERB
biomedich-939	113	11	as	as	ADP
biomedich-939	113	12	the	the	DET
biomedich-939	113	13	most	most	ADV
biomedich-939	113	14	favoured	favour	VERB
biomedich-939	113	15	technique	technique	NOUN
biomedich-939	113	16	to	to	PART
biomedich-939	113	17	evaluate	evaluate	VERB
biomedich-939	113	18	conjugated	conjugate	VERB
biomedich-939	113	19	organic	organic	ADJ
biomedich-939	113	20	compounds	compound	NOUN
biomedich-939	113	21	such	such	ADJ
biomedich-939	113	22	as	as	ADP
biomedich-939	113	23	quinoline	quinoline	NOUN
biomedich-939	113	24	and	and	CCONJ
biomedich-939	113	25	its	its	PRON
biomedich-939	113	26	derivatives	derivative	NOUN
biomedich-939	113	27	as	as	ADP
biomedich-939	113	28	the	the	DET
biomedich-939	113	29	ring	ring	NOUN
biomedich-939	113	30	in	in	ADP
biomedich-939	113	31	these	these	DET
biomedich-939	113	32	bioactive	bioactive	ADJ
biomedich-939	113	33	molecules	molecule	NOUN
biomedich-939	113	34	have	have	VERB
biomedich-939	113	35	the	the	DET
biomedich-939	113	36	ability	ability	NOUN
biomedich-939	113	37	to	to	PART
biomedich-939	113	38	absorb	absorb	VERB
biomedich-939	113	39	uv	uv	NOUN
biomedich-939	113	40	light	light	NOUN
biomedich-939	113	41	.	.	PUNCT
biomedich-939	114	1	few	few	ADJ
biomedich-939	114	2	coloured	coloured	ADJ
biomedich-939	114	3	derivatives	derivative	NOUN
biomedich-939	114	4	also	also	ADV
biomedich-939	114	5	absorb	absorb	VERB
biomedich-939	114	6	in	in	ADP
biomedich-939	114	7	the	the	DET
biomedich-939	114	8	visible	visible	ADJ
biomedich-939	114	9	region	region	NOUN
biomedich-939	114	10	thus	thus	ADV
biomedich-939	114	11	enabling	enable	VERB
biomedich-939	114	12	uv	uv	NOUN
biomedich-939	114	13	–	–	NOUN
biomedich-939	114	14	visible	visible	ADJ
biomedich-939	114	15	spectroscopy	spectroscopy	NOUN
biomedich-939	114	16	one	one	NUM
biomedich-939	114	17	of	of	ADP
biomedich-939	114	18	the	the	DET
biomedich-939	114	19	appropriate	appropriate	ADJ
biomedich-939	114	20	techniques	technique	NOUN
biomedich-939	114	21	their	their	PRON
biomedich-939	114	22	bioactivity	bioactivity	NOUN
biomedich-939	114	23	(	(	PUNCT
biomedich-939	114	24	ramešová	ramešová	PROPN
biomedich-939	114	25	et	et	PROPN
biomedich-939	114	26	al	al	PROPN
biomedich-939	114	27	.	.	PROPN
biomedich-939	114	28	,	,	PUNCT
biomedich-939	114	29	2012	2012	NUM
biomedich-939	114	30	)	)	PUNCT
biomedich-939	114	31	.	.	PUNCT
biomedich-939	115	1	total	total	ADJ
biomedich-939	115	2	antioxidant	antioxidant	ADJ
biomedich-939	115	3	activity	activity	NOUN
biomedich-939	115	4	is	be	AUX
biomedich-939	115	5	measured	measure	VERB
biomedich-939	115	6	by	by	ADP
biomedich-939	115	7	taking	take	VERB
biomedich-939	115	8	absorbance	absorbance	NOUN
biomedich-939	115	9	against	against	ADP
biomedich-939	115	10	water	water	NOUN
biomedich-939	115	11	to	to	PART
biomedich-939	115	12	calculate	calculate	VERB
biomedich-939	115	13	the	the	DET
biomedich-939	115	14	percentage	percentage	NOUN
biomedich-939	115	15	of	of	ADP
biomedich-939	115	16	inhibition	inhibition	NOUN
biomedich-939	115	17	.	.	PUNCT
biomedich-939	116	1	the	the	DET
biomedich-939	116	2	presence	presence	NOUN
biomedich-939	116	3	of	of	ADP
biomedich-939	116	4	the	the	DET
biomedich-939	116	5	carbonyl	carbonyl	NOUN
biomedich-939	116	6	groups	group	NOUN
biomedich-939	116	7	of	of	ADP
biomedich-939	116	8	the	the	DET
biomedich-939	116	9	2	2	NUM
biomedich-939	116	10	-	-	PUNCT
biomedich-939	116	11	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	116	12	also	also	ADV
biomedich-939	116	13	contributes	contribute	VERB
biomedich-939	116	14	to	to	ADP
biomedich-939	116	15	an	an	DET
biomedich-939	116	16	increase	increase	NOUN
biomedich-939	116	17	in	in	ADP
biomedich-939	116	18	the	the	DET
biomedich-939	116	19	absorbance	absorbance	NOUN
biomedich-939	116	20	.	.	PUNCT
biomedich-939	117	1	absorption	absorption	NOUN
biomedich-939	117	2	peak	peak	NOUN
biomedich-939	117	3	is	be	AUX
biomedich-939	117	4	associated	associate	VERB
biomedich-939	117	5	with	with	ADP
biomedich-939	117	6	an	an	DET
biomedich-939	117	7	electron	electron	NOUN
biomedich-939	117	8	transition	transition	NOUN
biomedich-939	117	9	from	from	ADP
biomedich-939	117	10	the	the	DET
biomedich-939	117	11	ground	ground	NOUN
biomedich-939	117	12	state	state	NOUN
biomedich-939	117	13	to	to	ADP
biomedich-939	117	14	its	its	PRON
biomedich-939	117	15	excited	excited	ADJ
biomedich-939	117	16	state	state	NOUN
biomedich-939	117	17	with	with	ADP
biomedich-939	117	18	corresponding	correspond	VERB
biomedich-939	117	19	excitation	excitation	NOUN
biomedich-939	117	20	energy	energy	NOUN
biomedich-939	117	21	and	and	CCONJ
biomedich-939	117	22	single	single	ADJ
biomedich-939	117	23	-	-	PUNCT
biomedich-939	117	24	point	point	NOUN
biomedich-939	117	25	(	(	PUNCT
biomedich-939	117	26	sp	sp	NOUN
biomedich-939	117	27	)	)	PUNCT
biomedich-939	117	28	energy	energy	NOUN
biomedich-939	117	29	calculation	calculation	NOUN
biomedich-939	117	30	provides	provide	VERB
biomedich-939	117	31	the	the	DET
biomedich-939	117	32	homo	homo	NOUN
biomedich-939	117	33	and	and	CCONJ
biomedich-939	117	34	lumo	lumo	NOUN
biomedich-939	117	35	energies	energy	NOUN
biomedich-939	117	36	as	as	SCONJ
biomedich-939	117	37	shown	show	VERB
biomedich-939	117	38	in	in	ADP
biomedich-939	117	39	table	table	NOUN
biomedich-939	117	40	1	1	NUM
biomedich-939	117	41	.	.	PUNCT
biomedich-939	118	1	it	it	PRON
biomedich-939	118	2	has	have	AUX
biomedich-939	118	3	been	be	AUX
biomedich-939	118	4	reported	report	VERB
biomedich-939	118	5	that	that	SCONJ
biomedich-939	118	6	ethanol	ethanol	NOUN
biomedich-939	118	7	and	and	CCONJ
biomedich-939	118	8	water	water	NOUN
biomedich-939	118	9	or	or	CCONJ
biomedich-939	118	10	a	a	DET
biomedich-939	118	11	mixture	mixture	NOUN
biomedich-939	118	12	of	of	ADP
biomedich-939	118	13	these	these	DET
biomedich-939	118	14	solvents	solvent	NOUN
biomedich-939	118	15	are	be	AUX
biomedich-939	118	16	suitable	suitable	ADJ
biomedich-939	118	17	since	since	SCONJ
biomedich-939	118	18	the	the	DET
biomedich-939	118	19	oxygen	oxygen	NOUN
biomedich-939	118	20	of	of	ADP
biomedich-939	118	21	the	the	DET
biomedich-939	118	22	carbonyl	carbonyl	NOUN
biomedich-939	118	23	groups	group	NOUN
biomedich-939	118	24	easily	easily	ADV
biomedich-939	118	25	bond	bond	VERB
biomedich-939	118	26	with	with	ADP
biomedich-939	118	27	the	the	DET
biomedich-939	118	28	hydrogen	hydrogen	NOUN
biomedich-939	118	29	of	of	ADP
biomedich-939	118	30	the	the	DET
biomedich-939	118	31	water	water	NOUN
biomedich-939	118	32	molecules	molecule	NOUN
biomedich-939	118	33	hence	hence	ADV
biomedich-939	118	34	their	their	PRON
biomedich-939	118	35	solubility	solubility	NOUN
biomedich-939	118	36	in	in	ADP
biomedich-939	118	37	the	the	DET
biomedich-939	118	38	solvents	solvent	NOUN
biomedich-939	118	39	are	be	AUX
biomedich-939	118	40	expected	expect	VERB
biomedich-939	118	41	(	(	PUNCT
biomedich-939	118	42	blume	blume	PROPN
biomedich-939	118	43	et	et	PROPN
biomedich-939	118	44	al	al	PROPN
biomedich-939	118	45	.	.	PROPN
biomedich-939	118	46	,	,	PUNCT
biomedich-939	118	47	1988	1988	NUM
biomedich-939	118	48	)	)	PUNCT
biomedich-939	118	49	.	.	PUNCT
biomedich-939	119	1	we	we	PRON
biomedich-939	119	2	chose	choose	VERB
biomedich-939	119	3	water	water	NOUN
biomedich-939	119	4	as	as	ADP
biomedich-939	119	5	the	the	DET
biomedich-939	119	6	solvent	solvent	NOUN
biomedich-939	119	7	for	for	ADP
biomedich-939	119	8	the	the	DET
biomedich-939	119	9	uv	uv	NOUN
biomedich-939	119	10	–	–	PUNCT
biomedich-939	119	11	vis	vis	X
biomedich-939	119	12	calculation	calculation	NOUN
biomedich-939	119	13	since	since	SCONJ
biomedich-939	119	14	this	this	PRON
biomedich-939	119	15	is	be	AUX
biomedich-939	119	16	preferred	prefer	VERB
biomedich-939	119	17	medium	medium	NOUN
biomedich-939	119	18	for	for	ADP
biomedich-939	119	19	drug	drug	NOUN
biomedich-939	119	20	delivery	delivery	NOUN
biomedich-939	119	21	.	.	PUNCT
biomedich-939	120	1	the	the	DET
biomedich-939	120	2	maximum	maximum	ADJ
biomedich-939	120	3	absorption	absorption	NOUN
biomedich-939	120	4	wavelength	wavelength	NOUN
biomedich-939	120	5	(	(	PUNCT
biomedich-939	120	6	λmax	λmax	NOUN
biomedich-939	120	7	)	)	PUNCT
biomedich-939	120	8	of	of	ADP
biomedich-939	120	9	the	the	DET
biomedich-939	120	10	2	2	NUM
biomedich-939	120	11	-	-	PUNCT
biomedich-939	120	12	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	120	13	in	in	ADP
biomedich-939	120	14	water	water	NOUN
biomedich-939	120	15	and	and	CCONJ
biomedich-939	120	16	the	the	DET
biomedich-939	120	17	excitation	excitation	NOUN
biomedich-939	120	18	energies	energy	NOUN
biomedich-939	120	19	show	show	VERB
biomedich-939	120	20	that	that	SCONJ
biomedich-939	120	21	maximum	maximum	ADJ
biomedich-939	120	22	wavelength	wavelength	NOUN
biomedich-939	120	23	of	of	ADP
biomedich-939	120	24	absorption	absorption	NOUN
biomedich-939	120	25	is	be	AUX
biomedich-939	120	26	inversely	inversely	ADV
biomedich-939	120	27	proportional	proportional	ADJ
biomedich-939	120	28	to	to	ADP
biomedich-939	120	29	the	the	DET
biomedich-939	120	30	excitation	excitation	NOUN
biomedich-939	120	31	energy	energy	NOUN
biomedich-939	120	32	as	as	SCONJ
biomedich-939	120	33	shown	show	VERB
biomedich-939	120	34	in	in	ADP
biomedich-939	120	35	table	table	NOUN
biomedich-939	120	36	2	2	NUM
biomedich-939	120	37	,	,	PUNCT
biomedich-939	120	38	figure	figure	VERB
biomedich-939	120	39	8	8	NUM
biomedich-939	120	40	.	.	PUNCT
biomedich-939	120	41	table	table	NOUN
biomedich-939	121	1	2	2	NUM
biomedich-939	121	2	.	.	PUNCT
biomedich-939	121	3	uv	uv	NOUN
biomedich-939	121	4	–	–	PUNCT
biomedich-939	121	5	visible	visible	ADJ
biomedich-939	121	6	spectroscopy	spectroscopy	NOUN
biomedich-939	121	7	.	.	PUNCT
biomedich-939	122	1	compound	compound	NOUN
biomedich-939	122	2	orbitals	orbital	NOUN
biomedich-939	122	3	extinction	extinction	PROPN
biomedich-939	122	4	coeff	coeff	PROPN
biomedich-939	122	5	oscil	oscil	PROPN
biomedich-939	122	6	strength	strength	PROPN
biomedich-939	122	7	1st	1st	ADJ
biomedich-939	122	8	excitation	excitation	NOUN
biomedich-939	122	9	e	e	X
biomedich-939	122	10	(	(	PUNCT
biomedich-939	122	11	ev	ev	INTJ
biomedich-939	122	12	)	)	PUNCT
biomedich-939	122	13	absorption	absorption	NOUN
biomedich-939	122	14	1	1	NUM
biomedich-939	122	15	79	79	NUM
biomedich-939	122	16	-80	-80	PUNCT
biomedich-939	122	17	0.548	0.548	NUM
biomedich-939	122	18	0.741	0.741	NUM
biomedich-939	122	19	3.3711	3.3711	NUM
biomedich-939	122	20	367.8	367.8	NUM
biomedich-939	122	21	2	2	NUM
biomedich-939	122	22	87	87	NUM
biomedich-939	122	23	88	88	NUM
biomedich-939	122	24	0.729	0.729	NUM
biomedich-939	122	25	0.854	0.854	NUM
biomedich-939	122	26	3.159	3.159	NUM
biomedich-939	122	27	392.5	392.5	NUM
biomedich-939	122	28	3	3	NUM
biomedich-939	122	29	91	91	NUM
biomedich-939	122	30	92	92	NUM
biomedich-939	122	31	0.89	0.89	NUM
biomedich-939	122	32	0.943	0.943	NUM
biomedich-939	122	33	2.865	2.865	NUM
biomedich-939	122	34	432.8	432.8	NUM
biomedich-939	122	35	4	4	NUM
biomedich-939	122	36	83	83	NUM
biomedich-939	122	37	84	84	NUM
biomedich-939	122	38	0.223	0.223	NUM
biomedich-939	122	39	0.472	0.472	NUM
biomedich-939	122	40	3.368	3.368	NUM
biomedich-939	122	41	368.2	368.2	NUM
biomedich-939	122	42	5	5	NUM
biomedich-939	122	43	95	95	NUM
biomedich-939	122	44	96	96	NUM
biomedich-939	122	45	0.791	0.791	NUM
biomedich-939	122	46	0.889	0.889	NUM
biomedich-939	122	47	3.186	3.186	NUM
biomedich-939	122	48	389.2	389.2	NUM
biomedich-939	122	49	6	6	NUM
biomedich-939	122	50	94	94	NUM
biomedich-939	122	51	-	-	SYM
biomedich-939	122	52	95	95	NUM
biomedich-939	122	53	0.059	0.059	NUM
biomedich-939	122	54	0.243	0.243	NUM
biomedich-939	122	55	3.375	3.375	NUM
biomedich-939	122	56	367.4	367.4	NUM
biomedich-939	122	57	7	7	NUM
biomedich-939	122	58	106	106	NUM
biomedich-939	122	59	-	-	SYM
biomedich-939	122	60	107	107	NUM
biomedich-939	122	61	0.94	0.94	NUM
biomedich-939	122	62	0.969	0.969	NUM
biomedich-939	122	63	2.785	2.785	NUM
biomedich-939	122	64	445.2	445.2	NUM
biomedich-939	122	65	8	8	NUM
biomedich-939	122	66	102	102	NUM
biomedich-939	122	67	103	103	NUM
biomedich-939	122	68	0.317	0.317	NUM
biomedich-939	122	69	0.563	0.563	NUM
biomedich-939	122	70	3.287	3.287	NUM
biomedich-939	122	71	377.2	377.2	NUM
biomedich-939	122	72	compound	compound	NOUN
biomedich-939	122	73	3	3	NUM
biomedich-939	122	74	compound	compound	NOUN
biomedich-939	122	75	5	5	NUM
biomedich-939	122	76	compound	compound	NOUN
biomedich-939	122	77	7	7	NUM
biomedich-939	122	78	figure	figure	NOUN
biomedich-939	122	79	6	6	NUM
biomedich-939	122	80	.	.	PUNCT
biomedich-939	122	81	representative	representative	ADJ
biomedich-939	122	82	homo	homo	NOUN
biomedich-939	122	83	-	-	PUNCT
biomedich-939	122	84	lumo	lumo	NOUN
biomedich-939	122	85	of	of	ADP
biomedich-939	122	86	synthesized	synthesize	VERB
biomedich-939	122	87	2	2	NUM
biomedich-939	122	88	-	-	PUNCT
biomedich-939	122	89	phenoxyquinoline-3	phenoxyquinoline-3	NOUN
biomedich-939	122	90	-	-	PUNCT
biomedich-939	122	91	carbaldehydes	carbaldehyde	NOUN
biomedich-939	122	92	.	.	PUNCT
biomedich-939	123	1	850	850	NUM
biomedich-939	123	2	biology	biology	NOUN
biomedich-939	123	3	,	,	PUNCT
biomedich-939	123	4	medicine	medicine	NOUN
biomedich-939	123	5	,	,	PUNCT
biomedich-939	123	6	&	&	CCONJ
biomedich-939	123	7	natural	natural	ADJ
biomedich-939	123	8	product	product	NOUN
biomedich-939	123	9	chemistry	chemistry	NOUN
biomedich-939	123	10	14	14	NUM
biomedich-939	123	11	(	(	PUNCT
biomedich-939	123	12	2	2	NUM
biomedich-939	123	13	)	)	PUNCT
biomedich-939	123	14	,	,	PUNCT
biomedich-939	123	15	2025	2025	NUM
biomedich-939	123	16	:	:	PUNCT
biomedich-939	123	17	843	843	NUM
biomedich-939	123	18	-	-	SYM
biomedich-939	123	19	856	856	NUM
biomedich-939	123	20	compound	compound	NOUN
biomedich-939	123	21	3	3	NUM
biomedich-939	123	22	compound	compound	NOUN
biomedich-939	123	23	5	5	NUM
biomedich-939	123	24	compound	compound	NOUN
biomedich-939	123	25	7	7	NUM
biomedich-939	123	26	figure	figure	NOUN
biomedich-939	123	27	7	7	NUM
biomedich-939	123	28	.	.	PUNCT
biomedich-939	123	29	representative	representative	ADJ
biomedich-939	123	30	molecular	molecular	ADJ
biomedich-939	123	31	electrostatic	electrostatic	ADJ
biomedich-939	123	32	potential	potential	NOUN
biomedich-939	123	33	(	(	PUNCT
biomedich-939	123	34	mep	mep	PROPN
biomedich-939	123	35	)	)	PUNCT
biomedich-939	123	36	surface	surface	NOUN
biomedich-939	123	37	of	of	ADP
biomedich-939	123	38	synthesized	synthesize	VERB
biomedich-939	123	39	2	2	NUM
biomedich-939	123	40	-	-	PUNCT
biomedich-939	123	41	phenoxyquinoline-3	phenoxyquinoline-3	NOUN
biomedich-939	123	42	-	-	PUNCT
biomedich-939	123	43	carbaldehydes	carbaldehyde	NOUN
biomedich-939	123	44	.	.	PUNCT
biomedich-939	124	1	figure	figure	VERB
biomedich-939	124	2	8	8	NUM
biomedich-939	124	3	.	.	PUNCT
biomedich-939	124	4	relationship	relationship	NOUN
biomedich-939	124	5	between	between	ADP
biomedich-939	124	6	excitation	excitation	NOUN
biomedich-939	124	7	energy	energy	NOUN
biomedich-939	124	8	and	and	CCONJ
biomedich-939	124	9	maximum	maximum	ADJ
biomedich-939	124	10	absorption	absorption	NOUN
biomedich-939	124	11	wavelength	wavelength	NOUN
biomedich-939	124	12	.	.	PUNCT
biomedich-939	125	1	considering	consider	VERB
biomedich-939	125	2	the	the	DET
biomedich-939	125	3	fact	fact	NOUN
biomedich-939	125	4	that	that	SCONJ
biomedich-939	125	5	the	the	DET
biomedich-939	125	6	promotion	promotion	NOUN
biomedich-939	125	7	of	of	ADP
biomedich-939	125	8	an	an	DET
biomedich-939	125	9	electron	electron	NOUN
biomedich-939	125	10	from	from	ADP
biomedich-939	125	11	the	the	DET
biomedich-939	125	12	ground	ground	NOUN
biomedich-939	125	13	state	state	NOUN
biomedich-939	125	14	to	to	ADP
biomedich-939	125	15	the	the	DET
biomedich-939	125	16	excited	excited	ADJ
biomedich-939	125	17	state	state	NOUN
biomedich-939	125	18	at	at	ADP
biomedich-939	125	19	longer	long	ADJ
biomedich-939	125	20	wavelengths	wavelength	NOUN
biomedich-939	125	21	require	require	VERB
biomedich-939	125	22	low	low	ADJ
biomedich-939	125	23	energy	energy	NOUN
biomedich-939	125	24	,	,	PUNCT
biomedich-939	125	25	it	it	PRON
biomedich-939	125	26	is	be	AUX
biomedich-939	125	27	hence	hence	ADV
biomedich-939	125	28	apparent	apparent	ADJ
biomedich-939	125	29	the	the	DET
biomedich-939	125	30	compound	compound	NOUN
biomedich-939	125	31	7	7	NUM
biomedich-939	125	32	with	with	ADP
biomedich-939	125	33	the	the	DET
biomedich-939	125	34	lowest	low	ADJ
biomedich-939	125	35	excitation	excitation	NOUN
biomedich-939	125	36	energy	energy	NOUN
biomedich-939	125	37	and	and	CCONJ
biomedich-939	125	38	the	the	DET
biomedich-939	125	39	highest	high	ADJ
biomedich-939	125	40	wavelength	wavelength	NOUN
biomedich-939	125	41	,	,	PUNCT
biomedich-939	125	42	implies	imply	VERB
biomedich-939	125	43	most	most	ADJ
biomedich-939	125	44	activity	activity	NOUN
biomedich-939	125	45	while	while	SCONJ
biomedich-939	125	46	6	6	NUM
biomedich-939	125	47	with	with	ADP
biomedich-939	125	48	highest	high	ADJ
biomedich-939	125	49	excitation	excitation	NOUN
biomedich-939	125	50	energies	energy	NOUN
biomedich-939	125	51	has	have	VERB
biomedich-939	125	52	lowest	low	ADJ
biomedich-939	125	53	activity	activity	NOUN
biomedich-939	125	54	.	.	PUNCT
biomedich-939	126	1	from	from	ADP
biomedich-939	126	2	the	the	DET
biomedich-939	126	3	time	time	NOUN
biomedich-939	126	4	-	-	PUNCT
biomedich-939	126	5	dependent	dependent	ADJ
biomedich-939	126	6	density	density	NOUN
biomedich-939	126	7	functional	functional	ADJ
biomedich-939	126	8	theory	theory	NOUN
biomedich-939	126	9	(	(	PUNCT
biomedich-939	126	10	td	td	NOUN
biomedich-939	126	11	-	-	PUNCT
biomedich-939	126	12	dft	dft	NOUN
biomedich-939	126	13	)	)	PUNCT
biomedich-939	126	14	calculations	calculation	NOUN
biomedich-939	126	15	,	,	PUNCT
biomedich-939	126	16	electronic	electronic	ADJ
biomedich-939	126	17	transitions	transition	NOUN
biomedich-939	126	18	information	information	NOUN
biomedich-939	126	19	including	include	VERB
biomedich-939	126	20	which	which	DET
biomedich-939	126	21	transition	transition	NOUN
biomedich-939	126	22	orbital	orbital	NOUN
biomedich-939	126	23	was	be	AUX
biomedich-939	126	24	involved	involve	VERB
biomedich-939	126	25	,	,	PUNCT
biomedich-939	126	26	oscillator	oscillator	NOUN
biomedich-939	126	27	strength	strength	NOUN
biomedich-939	126	28	,	,	PUNCT
biomedich-939	126	29	extinction	extinction	NOUN
biomedich-939	126	30	coefficient	coefficient	NOUN
biomedich-939	126	31	,	,	PUNCT
biomedich-939	126	32	excitation	excitation	NOUN
biomedich-939	126	33	state	state	NOUN
biomedich-939	126	34	energies	energy	NOUN
biomedich-939	126	35	and	and	CCONJ
biomedich-939	126	36	the	the	DET
biomedich-939	126	37	electronic	electronic	ADJ
biomedich-939	126	38	states	state	NOUN
biomedich-939	126	39	of	of	ADP
biomedich-939	126	40	the	the	DET
biomedich-939	126	41	transitions	transition	NOUN
biomedich-939	126	42	support	support	VERB
biomedich-939	126	43	the	the	DET
biomedich-939	126	44	bioactivity	bioactivity	NOUN
biomedich-939	126	45	of	of	ADP
biomedich-939	126	46	compound	compound	NOUN
biomedich-939	126	47	7	7	NUM
biomedich-939	126	48	.	.	PUNCT
biomedich-939	126	49	molar	molar	ADJ
biomedich-939	126	50	extinction	extinction	NOUN
biomedich-939	126	51	coefficient	coefficient	NOUN
biomedich-939	126	52	,	,	PUNCT
biomedich-939	126	53	also	also	ADV
biomedich-939	126	54	known	know	VERB
biomedich-939	126	55	as	as	ADP
biomedich-939	126	56	molar	molar	ADJ
biomedich-939	126	57	absorptivity	absorptivity	NOUN
biomedich-939	126	58	,	,	PUNCT
biomedich-939	126	59	is	be	AUX
biomedich-939	126	60	an	an	DET
biomedich-939	126	61	intrinsic	intrinsic	ADJ
biomedich-939	126	62	property	property	NOUN
biomedich-939	126	63	of	of	ADP
biomedich-939	126	64	the	the	DET
biomedich-939	126	65	molecule	molecule	NOUN
biomedich-939	126	66	which	which	PRON
biomedich-939	126	67	is	be	AUX
biomedich-939	126	68	dependent	dependent	ADJ
biomedich-939	126	69	on	on	ADP
biomedich-939	126	70	the	the	DET
biomedich-939	126	71	atomic	atomic	NOUN
biomedich-939	126	72	,	,	PUNCT
biomedich-939	126	73	chemical	chemical	NOUN
biomedich-939	126	74	,	,	PUNCT
biomedich-939	126	75	and	and	CCONJ
biomedich-939	126	76	structural	structural	ADJ
biomedich-939	126	77	composition	composition	NOUN
biomedich-939	126	78	.	.	PUNCT
biomedich-939	127	1	it	it	PRON
biomedich-939	127	2	determines	determine	VERB
biomedich-939	127	3	how	how	SCONJ
biomedich-939	127	4	strongly	strongly	ADV
biomedich-939	127	5	a	a	DET
biomedich-939	127	6	species	species	NOUN
biomedich-939	127	7	absorbs	absorb	VERB
biomedich-939	127	8	or	or	CCONJ
biomedich-939	127	9	reflects	reflect	VERB
biomedich-939	127	10	radiation	radiation	NOUN
biomedich-939	127	11	or	or	CCONJ
biomedich-939	127	12	light	light	NOUN
biomedich-939	127	13	at	at	ADP
biomedich-939	127	14	a	a	DET
biomedich-939	127	15	particular	particular	ADJ
biomedich-939	127	16	wavelength	wavelength	NOUN
biomedich-939	127	17	(	(	PUNCT
biomedich-939	127	18	ozdemir	ozdemir	PROPN
biomedich-939	127	19	&	&	CCONJ
biomedich-939	127	20	sadoglu	sadoglu	PROPN
biomedich-939	127	21	,	,	PUNCT
biomedich-939	127	22	2018	2018	NUM
biomedich-939	127	23	)	)	PUNCT
biomedich-939	127	24	.	.	PUNCT
biomedich-939	128	1	compounds	compound	VERB
biomedich-939	128	2	3	3	NUM
biomedich-939	128	3	,	,	PUNCT
biomedich-939	128	4	5	5	NUM
biomedich-939	128	5	and	and	CCONJ
biomedich-939	128	6	7	7	NUM
biomedich-939	128	7	have	have	VERB
biomedich-939	128	8	high	high	ADJ
biomedich-939	128	9	molar	molar	ADJ
biomedich-939	128	10	absorptivity	absorptivity	NOUN
biomedich-939	128	11	(	(	PUNCT
biomedich-939	128	12	>	>	X
biomedich-939	128	13	0.5	0.5	NUM
biomedich-939	128	14	ev	ev	NOUN
biomedich-939	128	15	)	)	PUNCT
biomedich-939	128	16	,	,	PUNCT
biomedich-939	128	17	hence	hence	ADV
biomedich-939	128	18	,	,	PUNCT
biomedich-939	128	19	they	they	PRON
biomedich-939	128	20	strongly	strongly	ADV
biomedich-939	128	21	attenuate	attenuate	VERB
biomedich-939	128	22	light	light	NOUN
biomedich-939	128	23	while	while	SCONJ
biomedich-939	128	24	4	4	NUM
biomedich-939	128	25	and	and	CCONJ
biomedich-939	128	26	6	6	NUM
biomedich-939	128	27	have	have	VERB
biomedich-939	128	28	extinction	extinction	NOUN
biomedich-939	128	29	coefficient	coefficient	NOUN
biomedich-939	128	30	less	less	ADJ
biomedich-939	128	31	than	than	ADP
biomedich-939	128	32	0.5	0.5	NUM
biomedich-939	128	33	.	.	PUNCT
biomedich-939	129	1	oscillator	oscillator	NOUN
biomedich-939	129	2	strength	strength	NOUN
biomedich-939	129	3	is	be	AUX
biomedich-939	129	4	a	a	DET
biomedich-939	129	5	dimensionless	dimensionless	NOUN
biomedich-939	129	6	quantity	quantity	NOUN
biomedich-939	129	7	that	that	PRON
biomedich-939	129	8	expresses	express	VERB
biomedich-939	129	9	the	the	DET
biomedich-939	129	10	probability	probability	NOUN
biomedich-939	129	11	of	of	ADP
biomedich-939	129	12	absorption	absorption	NOUN
biomedich-939	129	13	or	or	CCONJ
biomedich-939	129	14	emission	emission	NOUN
biomedich-939	129	15	transitions	transition	NOUN
biomedich-939	129	16	between	between	ADP
biomedich-939	129	17	energy	energy	NOUN
biomedich-939	129	18	levels	level	NOUN
biomedich-939	129	19	of	of	ADP
biomedich-939	129	20	an	an	DET
biomedich-939	129	21	atom	atom	NOUN
biomedich-939	129	22	or	or	CCONJ
biomedich-939	129	23	molecule	molecule	NOUN
biomedich-939	129	24	,	,	PUNCT
biomedich-939	129	25	that	that	ADV
biomedich-939	129	26	is	is	ADV
biomedich-939	129	27	,	,	PUNCT
biomedich-939	129	28	a	a	DET
biomedich-939	129	29	measure	measure	NOUN
biomedich-939	129	30	of	of	ADP
biomedich-939	129	31	excitation	excitation	NOUN
biomedich-939	129	32	probability	probability	NOUN
biomedich-939	129	33	(	(	PUNCT
biomedich-939	129	34	nizar	nizar	PROPN
biomedich-939	129	35	et	et	PROPN
biomedich-939	129	36	al	al	PROPN
biomedich-939	129	37	.	.	PROPN
biomedich-939	129	38	,	,	PUNCT
biomedich-939	129	39	2021	2021	NUM
biomedich-939	129	40	)	)	PUNCT
biomedich-939	129	41	.	.	PUNCT
biomedich-939	130	1	the	the	DET
biomedich-939	130	2	high	high	ADJ
biomedich-939	130	3	oscillator	oscillator	NOUN
biomedich-939	130	4	strengths	strength	NOUN
biomedich-939	130	5	which	which	PRON
biomedich-939	130	6	indicate	indicate	VERB
biomedich-939	130	7	the	the	DET
biomedich-939	130	8	high	high	ADJ
biomedich-939	130	9	probability	probability	NOUN
biomedich-939	130	10	of	of	ADP
biomedich-939	130	11	excitation	excitation	NOUN
biomedich-939	130	12	gave	give	VERB
biomedich-939	130	13	the	the	DET
biomedich-939	130	14	strongest	strong	ADJ
biomedich-939	130	15	transitions	transition	NOUN
biomedich-939	130	16	(	(	PUNCT
biomedich-939	130	17	which	which	PRON
biomedich-939	130	18	are	be	AUX
biomedich-939	130	19	presented	present	VERB
biomedich-939	130	20	in	in	ADP
biomedich-939	130	21	table	table	NOUN
biomedich-939	130	22	1	1	NUM
biomedich-939	130	23	)	)	PUNCT
biomedich-939	130	24	compared	compare	VERB
biomedich-939	130	25	to	to	ADP
biomedich-939	130	26	other	other	ADJ
biomedich-939	130	27	transitions	transition	NOUN
biomedich-939	130	28	.	.	PUNCT
biomedich-939	131	1	molecular	molecular	ADJ
biomedich-939	131	2	and	and	CCONJ
biomedich-939	131	3	physicochemical	physicochemical	ADJ
biomedich-939	131	4	properties	property	NOUN
biomedich-939	131	5	adsorption	adsorption	NOUN
biomedich-939	131	6	,	,	PUNCT
biomedich-939	131	7	distribution	distribution	NOUN
biomedich-939	131	8	,	,	PUNCT
biomedich-939	131	9	metabolism	metabolism	NOUN
biomedich-939	131	10	and	and	CCONJ
biomedich-939	131	11	excretion	excretion	NOUN
biomedich-939	131	12	(	(	PUNCT
biomedich-939	131	13	adme	adme	NOUN
biomedich-939	131	14	)	)	PUNCT
biomedich-939	131	15	protocols	protocol	NOUN
biomedich-939	131	16	play	play	VERB
biomedich-939	131	17	crucial	crucial	ADJ
biomedich-939	131	18	roles	role	NOUN
biomedich-939	131	19	in	in	ADP
biomedich-939	131	20	the	the	DET
biomedich-939	131	21	development	development	NOUN
biomedich-939	131	22	of	of	ADP
biomedich-939	131	23	new	new	ADJ
biomedich-939	131	24	drug	drug	NOUN
biomedich-939	131	25	molecules	molecule	NOUN
biomedich-939	131	26	as	as	SCONJ
biomedich-939	131	27	they	they	PRON
biomedich-939	131	28	outline	outline	VERB
biomedich-939	131	29	the	the	DET
biomedich-939	131	30	dose	dose	NOUN
biomedich-939	131	31	amounts	amount	NOUN
biomedich-939	131	32	,	,	PUNCT
biomedich-939	131	33	intervals	interval	NOUN
biomedich-939	131	34	and	and	CCONJ
biomedich-939	131	35	overall	overall	ADJ
biomedich-939	131	36	safety	safety	NOUN
biomedich-939	131	37	of	of	ADP
biomedich-939	131	38	oral	oral	ADJ
biomedich-939	131	39	drug	drug	NOUN
biomedich-939	131	40	administration	administration	NOUN
biomedich-939	131	41	(	(	PUNCT
biomedich-939	131	42	mcginnity	mcginnity	NOUN
biomedich-939	131	43	et	et	PROPN
biomedich-939	131	44	al	al	PROPN
biomedich-939	131	45	.	.	PROPN
biomedich-939	131	46	,	,	PUNCT
biomedich-939	131	47	2007	2007	NUM
biomedich-939	131	48	)	)	PUNCT
biomedich-939	131	49	making	make	VERB
biomedich-939	131	50	the	the	DET
biomedich-939	131	51	determination	determination	NOUN
biomedich-939	131	52	of	of	ADP
biomedich-939	131	53	physicochemical	physicochemical	ADJ
biomedich-939	131	54	properties	property	NOUN
biomedich-939	131	55	feasible	feasible	ADJ
biomedich-939	131	56	(	(	PUNCT
biomedich-939	131	57	nithiyanantham	nithiyanantham	NOUN
biomedich-939	131	58	et	et	PROPN
biomedich-939	131	59	al	al	PROPN
biomedich-939	131	60	.	.	PROPN
biomedich-939	131	61	,	,	PUNCT
biomedich-939	131	62	2015	2015	NUM
biomedich-939	131	63	)	)	PUNCT
biomedich-939	131	64	thus	thus	ADV
biomedich-939	131	65	providing	provide	VERB
biomedich-939	131	66	desirable	desirable	ADJ
biomedich-939	131	67	balance	balance	NOUN
biomedich-939	131	68	of	of	ADP
biomedich-939	131	69	physicochemical	physicochemical	ADJ
biomedich-939	131	70	properties	property	NOUN
biomedich-939	131	71	for	for	ADP
biomedich-939	131	72	safe	safe	ADJ
biomedich-939	131	73	drug	drug	NOUN
biomedich-939	131	74	administration	administration	NOUN
biomedich-939	131	75	(	(	PUNCT
biomedich-939	131	76	belaidi	belaidi	VERB
biomedich-939	131	77	et	et	NOUN
biomedich-939	131	78	al	al	PROPN
biomedich-939	131	79	.	.	PROPN
biomedich-939	131	80	,	,	PUNCT
biomedich-939	131	81	2016	2016	NUM
biomedich-939	131	82	)	)	PUNCT
biomedich-939	131	83	.	.	PUNCT
biomedich-939	132	1	the	the	DET
biomedich-939	132	2	logarithm	logarithm	NOUN
biomedich-939	132	3	of	of	ADP
biomedich-939	132	4	octanol	octanol	NOUN
biomedich-939	132	5	–	–	PUNCT
biomedich-939	132	6	water	water	NOUN
biomedich-939	132	7	partition	partition	NOUN
biomedich-939	132	8	coefficient	coefficient	NOUN
biomedich-939	132	9	(	(	PUNCT
biomedich-939	132	10	log	log	NOUN
biomedich-939	132	11	pow	pow	NOUN
biomedich-939	132	12	)	)	PUNCT
biomedich-939	132	13	is	be	AUX
biomedich-939	132	14	a	a	DET
biomedich-939	132	15	broadly	broadly	ADV
biomedich-939	132	16	acknowledged	acknowledge	VERB
biomedich-939	132	17	measure	measure	NOUN
biomedich-939	132	18	of	of	ADP
biomedich-939	132	19	lipophilicity	lipophilicity	NOUN
biomedich-939	132	20	and	and	CCONJ
biomedich-939	132	21	is	be	AUX
biomedich-939	132	22	determined	determine	VERB
biomedich-939	132	23	for	for	ADP
biomedich-939	132	24	numerous	numerous	ADJ
biomedich-939	132	25	compounds	compound	NOUN
biomedich-939	132	26	(	(	PUNCT
biomedich-939	132	27	poole	poole	NOUN
biomedich-939	132	28	&	&	CCONJ
biomedich-939	132	29	poole	poole	PROPN
biomedich-939	132	30	,	,	PUNCT
biomedich-939	132	31	2003	2003	NUM
biomedich-939	132	32	)	)	PUNCT
biomedich-939	132	33	.	.	PUNCT
biomedich-939	133	1	pow	pow	PROPN
biomedich-939	133	2	is	be	AUX
biomedich-939	133	3	the	the	DET
biomedich-939	133	4	concentration	concentration	NOUN
biomedich-939	133	5	ratio	ratio	NOUN
biomedich-939	133	6	of	of	ADP
biomedich-939	133	7	the	the	DET
biomedich-939	133	8	compound	compound	NOUN
biomedich-939	133	9	distributed	distribute	VERB
biomedich-939	133	10	between	between	ADP
biomedich-939	133	11	n	n	NOUN
biomedich-939	133	12	-	-	PUNCT
biomedich-939	133	13	octanol	octanol	NOUN
biomedich-939	133	14	and	and	CCONJ
biomedich-939	133	15	water	water	NOUN
biomedich-939	133	16	.	.	PUNCT
biomedich-939	134	1	(	(	PUNCT
biomedich-939	134	2	ribeiro	ribeiro	PROPN
biomedich-939	134	3	et	et	PROPN
biomedich-939	134	4	al	al	PROPN
biomedich-939	134	5	.	.	PROPN
biomedich-939	134	6	,	,	PUNCT
biomedich-939	134	7	2011	2011	NUM
biomedich-939	134	8	;	;	PUNCT
biomedich-939	134	9	jalan	jalan	PROPN
biomedich-939	134	10	et	et	PROPN
biomedich-939	134	11	al	al	PROPN
biomedich-939	134	12	.	.	PROPN
biomedich-939	134	13	,	,	PUNCT
biomedich-939	134	14	2010	2010	NUM
biomedich-939	134	15	)	)	PUNCT
biomedich-939	134	16	.	.	PUNCT
biomedich-939	135	1	the	the	DET
biomedich-939	135	2	partition	partition	NOUN
biomedich-939	135	3	coefficient	coefficient	NOUN
biomedich-939	135	4	is	be	AUX
biomedich-939	135	5	an	an	DET
biomedich-939	135	6	exceedingly	exceedingly	ADV
biomedich-939	135	7	important	important	ADJ
biomedich-939	135	8	physicochemical	physicochemical	ADJ
biomedich-939	135	9	parameter	parameter	NOUN
biomedich-939	135	10	in	in	ADP
biomedich-939	135	11	medicinal	medicinal	ADJ
biomedich-939	135	12	chemistry	chemistry	NOUN
biomedich-939	135	13	,	,	PUNCT
biomedich-939	135	14	beneficial	beneficial	ADJ
biomedich-939	135	15	in	in	ADP
biomedich-939	135	16	pharmacology	pharmacology	NOUN
biomedich-939	135	17	and	and	CCONJ
biomedich-939	135	18	toxicology	toxicology	NOUN
biomedich-939	135	19	,	,	PUNCT
biomedich-939	135	20	as	as	SCONJ
biomedich-939	135	21	long	long	ADV
biomedich-939	135	22	-	-	PUNCT
biomedich-939	135	23	established	establish	VERB
biomedich-939	135	24	by	by	ADP
biomedich-939	135	25	a	a	DET
biomedich-939	135	26	large	large	ADJ
biomedich-939	135	27	numeral	numeral	ADJ
biomedich-939	135	28	of	of	ADP
biomedich-939	135	29	literature	literature	NOUN
biomedich-939	135	30	data	datum	NOUN
biomedich-939	135	31	(	(	PUNCT
biomedich-939	135	32	balaz	balaz	ADJ
biomedich-939	135	33	,	,	PUNCT
biomedich-939	135	34	2009	2009	NUM
biomedich-939	135	35	;	;	PUNCT
biomedich-939	135	36	sangster	sangster	NOUN
biomedich-939	135	37	,	,	PUNCT
biomedich-939	135	38	1997	1997	NUM
biomedich-939	135	39	)	)	PUNCT
biomedich-939	135	40	.	.	PUNCT
biomedich-939	136	1	7	7	NUM
biomedich-939	136	2	2	2	NUM
biomedich-939	136	3	3	3	NUM
biomedich-939	136	4	4	4	NUM
biomedich-939	136	5	5	5	NUM
biomedich-939	136	6	6	6	NUM
biomedich-939	136	7	1	1	NUM
biomedich-939	136	8	8	8	NUM
biomedich-939	136	9	2,8	2,8	NUM
biomedich-939	136	10	3	3	NUM
biomedich-939	136	11	3,2	3,2	NUM
biomedich-939	136	12	3,4	3,4	NUM
biomedich-939	136	13	3,6	3,6	NUM
biomedich-939	136	14	3,8	3,8	NUM
biomedich-939	136	15	4	4	NUM
biomedich-939	136	16	315	315	NUM
biomedich-939	136	17	335	335	NUM
biomedich-939	136	18	355	355	NUM
biomedich-939	136	19	375	375	NUM
biomedich-939	136	20	395	395	NUM
biomedich-939	136	21	415	415	NUM
biomedich-939	136	22	435	435	NUM
biomedich-939	136	23	ex	ex	X
biomedich-939	136	24	ci	ci	NOUN
biomedich-939	136	25	ta	ta	X
biomedich-939	136	26	ti	ti	PROPN
biomedich-939	136	27	o	o	PROPN
biomedich-939	136	28	n	n	ADP
biomedich-939	136	29	e	e	NOUN
biomedich-939	136	30	n	n	CCONJ
biomedich-939	136	31	er	er	INTJ
biomedich-939	136	32	gy	gy	PROPN
biomedich-939	136	33	absorption	absorption	NOUN
biomedich-939	136	34	aina	aina	PROPN
biomedich-939	136	35	et	et	PROPN
biomedich-939	136	36	al	al	PROPN
biomedich-939	136	37	.	.	PROPN
biomedich-939	136	38	–	–	PUNCT
biomedich-939	136	39	dft	dft	PROPN
biomedich-939	136	40	study	study	NOUN
biomedich-939	136	41	and	and	CCONJ
biomedich-939	136	42	admet	admet	PROPN
biomedich-939	136	43	investigation	investigation	NOUN
biomedich-939	136	44	of	of	ADP
biomedich-939	136	45	bioactive	bioactive	ADJ
biomedich-939	136	46	2	2	NUM
biomedich-939	136	47	-	-	PUNCT
biomedich-939	136	48	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	136	49	851	851	NUM
biomedich-939	136	50	table	table	NOUN
biomedich-939	136	51	3	3	NUM
biomedich-939	136	52	.	.	PUNCT
biomedich-939	136	53	physicochemical	physicochemical	ADJ
biomedich-939	136	54	parameters	parameter	NOUN
biomedich-939	136	55	for	for	ADP
biomedich-939	136	56	2	2	NUM
biomedich-939	136	57	-	-	PUNCT
biomedich-939	136	58	phenoxyquinoline-3	phenoxyquinoline-3	NOUN
biomedich-939	136	59	-	-	PUNCT
biomedich-939	136	60	carbaldehydes	carbaldehyde	NOUN
biomedich-939	136	61	.	.	PUNCT
biomedich-939	137	1	cp	cp	PROPN
biomedich-939	137	2	milog	milog	VERB
biomedich-939	137	3	a	a	DET
biomedich-939	137	4	tpsa	tpsa	NOUN
biomedich-939	137	5	b	b	PROPN
biomedich-939	137	6	natoms	natom	NOUN
biomedich-939	137	7	c	c	NOUN
biomedich-939	137	8	mw	mw	VERB
biomedich-939	137	9	d	d	VERB
biomedich-939	137	10	non	non	ADJ
biomedich-939	137	11	e	e	PROPN
biomedich-939	137	12	nohnh	nohnh	NOUN
biomedich-939	137	13	f	f	PROPN
biomedich-939	137	14	nviolat	nviolat	PROPN
biomedich-939	137	15	g	g	PROPN
biomedich-939	137	16	nrotb	nrotb	PROPN
biomedich-939	138	1	h	h	NOUN
biomedich-939	138	2	vol	vol	NOUN
biomedich-939	138	3	i	i	NOUN
biomedich-939	138	4	1	1	NUM
biomedich-939	138	5	3.06	3.06	NUM
biomedich-939	138	6	65.5	65.5	NUM
biomedich-939	138	7	23	23	NUM
biomedich-939	138	8	307.31	307.31	NUM
biomedich-939	138	9	5	5	NUM
biomedich-939	138	10	0	0	NUM
biomedich-939	138	11	0	0	NUM
biomedich-939	138	12	5	5	NUM
biomedich-939	138	13	267.79	267.79	NUM
biomedich-939	138	14	2	2	NUM
biomedich-939	138	15	3.46	3.46	NUM
biomedich-939	138	16	65.5	65.5	NUM
biomedich-939	138	17	24	24	NUM
biomedich-939	138	18	321.33	321.33	NUM
biomedich-939	138	19	5	5	NUM
biomedich-939	138	20	0	0	NUM
biomedich-939	138	21	0	0	NUM
biomedich-939	138	22	5	5	NUM
biomedich-939	138	23	284.35	284.35	NUM
biomedich-939	138	24	3	3	NUM
biomedich-939	138	25	2.65	2.65	NUM
biomedich-939	138	26	65.5	65.5	NUM
biomedich-939	138	27	25	25	NUM
biomedich-939	138	28	339.32	339.32	NUM
biomedich-939	138	29	5	5	NUM
biomedich-939	138	30	0	0	NUM
biomedich-939	138	31	0	0	NUM
biomedich-939	138	32	5	5	NUM
biomedich-939	138	33	289.28	289.28	NUM
biomedich-939	138	34	4	4	NUM
biomedich-939	138	35	3.49	3.49	NUM
biomedich-939	138	36	65.5	65.5	NUM
biomedich-939	138	37	24	24	NUM
biomedich-939	138	38	321.33	321.33	NUM
biomedich-939	138	39	5	5	NUM
biomedich-939	138	40	0	0	NUM
biomedich-939	138	41	0	0	NUM
biomedich-939	138	42	5	5	NUM
biomedich-939	138	43	284.35	284.35	NUM
biomedich-939	138	44	5	5	NUM
biomedich-939	138	45	5.59	5.59	NUM
biomedich-939	138	46	56.27	56.27	NUM
biomedich-939	138	47	28	28	NUM
biomedich-939	138	48	367.4	367.4	NUM
biomedich-939	138	49	4	4	NUM
biomedich-939	138	50	0	0	NUM
biomedich-939	138	51	1	1	NUM
biomedich-939	138	52	5	5	NUM
biomedich-939	138	53	330.21	330.21	NUM
biomedich-939	138	54	6	6	NUM
biomedich-939	138	55	2.37	2.37	NUM
biomedich-939	138	56	91.81	91.81	NUM
biomedich-939	138	57	27	27	NUM
biomedich-939	138	58	365.34	365.34	NUM
biomedich-939	138	59	7	7	NUM
biomedich-939	138	60	0	0	NUM
biomedich-939	138	61	0	0	NUM
biomedich-939	138	62	7	7	NUM
biomedich-939	138	63	312.31	312.31	NUM
biomedich-939	138	64	7	7	NUM
biomedich-939	138	65	3.8	3.8	NUM
biomedich-939	138	66	101.04	101.04	NUM
biomedich-939	138	67	30	30	NUM
biomedich-939	138	68	409.39	409.39	NUM
biomedich-939	138	69	8	8	NUM
biomedich-939	138	70	0	0	NUM
biomedich-939	138	71	0	0	NUM
biomedich-939	138	72	8	8	NUM
biomedich-939	138	73	354.42	354.42	NUM
biomedich-939	138	74	8	8	NUM
biomedich-939	138	75	1.94	1.94	NUM
biomedich-939	138	76	91.81	91.81	NUM
biomedich-939	138	77	29	29	NUM
biomedich-939	138	78	397.36	397.36	NUM
biomedich-939	138	79	7	7	NUM
biomedich-939	138	80	0	0	NUM
biomedich-939	138	81	0	0	NUM
biomedich-939	138	82	7	7	NUM
biomedich-939	138	83	333.81	333.81	NUM
biomedich-939	138	84	a.	a.	NOUN
biomedich-939	138	85	octanol	octanol	NOUN
biomedich-939	138	86	–	–	PUNCT
biomedich-939	138	87	water	water	NOUN
biomedich-939	138	88	partition	partition	NOUN
biomedich-939	138	89	coefficient	coefficient	NOUN
biomedich-939	138	90	as	as	SCONJ
biomedich-939	138	91	reported	report	VERB
biomedich-939	138	92	in	in	ADP
biomedich-939	138	93	molinspiration	molinspiration	NOUN
biomedich-939	138	94	.	.	PUNCT
biomedich-939	139	1	b.	b.	PROPN
biomedich-939	139	2	total	total	ADJ
biomedich-939	139	3	polar	polar	PROPN
biomedich-939	139	4	surface	surface	NOUN
biomedich-939	139	5	area	area	NOUN
biomedich-939	139	6	in	in	ADP
biomedich-939	139	7	å2	å2	PROPN
biomedich-939	139	8	.	.	PUNCT
biomedich-939	140	1	c.	c.	PROPN
biomedich-939	140	2	total	total	ADJ
biomedich-939	140	3	number	number	NOUN
biomedich-939	140	4	of	of	ADP
biomedich-939	140	5	atoms	atom	NOUN
biomedich-939	140	6	.	.	PUNCT
biomedich-939	141	1	d.	d.	PROPN
biomedich-939	141	2	molecular	molecular	ADJ
biomedich-939	141	3	weight	weight	NOUN
biomedich-939	141	4	in	in	ADP
biomedich-939	141	5	g	g	PROPN
biomedich-939	141	6	mol—1	mol—1	PROPN
biomedich-939	141	7	.	.	PUNCT
biomedich-939	142	1	e.	e.	PROPN
biomedich-939	142	2	number	number	PROPN
biomedich-939	142	3	of	of	ADP
biomedich-939	142	4	hydrogen	hydrogen	NOUN
biomedich-939	142	5	bond	bond	NOUN
biomedich-939	142	6	acceptors	acceptor	NOUN
biomedich-939	142	7	.	.	PUNCT
biomedich-939	143	1	f.	f.	PROPN
biomedich-939	143	2	number	number	NOUN
biomedich-939	143	3	of	of	ADP
biomedich-939	143	4	hydrogen	hydrogen	NOUN
biomedich-939	143	5	bond	bond	NOUN
biomedich-939	143	6	donors	donor	NOUN
biomedich-939	143	7	.	.	PUNCT
biomedich-939	144	1	g.	g.	NOUN
biomedich-939	144	2	number	number	NOUN
biomedich-939	144	3	of	of	ADP
biomedich-939	144	4	violations	violation	NOUN
biomedich-939	144	5	to	to	ADP
biomedich-939	144	6	lipinski	lipinski	PROPN
biomedich-939	144	7	’s	’s	PART
biomedich-939	144	8	rule	rule	NOUN
biomedich-939	144	9	of	of	ADP
biomedich-939	144	10	5	5	NUM
biomedich-939	144	11	.	.	PUNCT
biomedich-939	144	12	h.	h.	NOUN
biomedich-939	144	13	number	number	NOUN
biomedich-939	144	14	of	of	ADP
biomedich-939	144	15	rotatable	rotatable	ADJ
biomedich-939	144	16	bonds	bond	NOUN
biomedich-939	144	17	.	.	PUNCT
biomedich-939	145	1	i.	i.	PROPN
biomedich-939	145	2	volume	volume	NOUN
biomedich-939	145	3	in	in	ADP
biomedich-939	145	4	å3	å3	PROPN
biomedich-939	145	5	.	.	PUNCT
biomedich-939	146	1	active	active	ADJ
biomedich-939	146	2	organic	organic	ADJ
biomedich-939	146	3	compounds	compound	NOUN
biomedich-939	146	4	have	have	AUX
biomedich-939	146	5	log	log	VERB
biomedich-939	146	6	p	p	NOUN
biomedich-939	146	7	value	value	NOUN
biomedich-939	146	8	of	of	ADP
biomedich-939	146	9	1.6	1.6	NUM
biomedich-939	146	10	upward	upward	ADV
biomedich-939	146	11	(	(	PUNCT
biomedich-939	146	12	buddensiek	buddensiek	NOUN
biomedich-939	146	13	et	et	PROPN
biomedich-939	146	14	al	al	PROPN
biomedich-939	146	15	.	.	PROPN
biomedich-939	146	16	,	,	PUNCT
biomedich-939	146	17	2021	2021	NUM
biomedich-939	146	18	)	)	PUNCT
biomedich-939	146	19	implying	imply	VERB
biomedich-939	146	20	a	a	DET
biomedich-939	146	21	reduced	reduce	VERB
biomedich-939	146	22	inhibitory	inhibitory	ADJ
biomedich-939	146	23	activity	activity	NOUN
biomedich-939	146	24	at	at	ADP
biomedich-939	146	25	values	value	NOUN
biomedich-939	146	26	below	below	ADV
biomedich-939	146	27	.	.	PUNCT
biomedich-939	147	1	it	it	PRON
biomedich-939	147	2	is	be	AUX
biomedich-939	147	3	noteworthy	noteworthy	ADJ
biomedich-939	147	4	to	to	PART
biomedich-939	147	5	see	see	VERB
biomedich-939	147	6	compounds	compound	NOUN
biomedich-939	147	7	1	1	NUM
biomedich-939	147	8	,	,	PUNCT
biomedich-939	147	9	2	2	NUM
biomedich-939	147	10	,	,	PUNCT
biomedich-939	147	11	4	4	NUM
biomedich-939	147	12	,	,	PUNCT
biomedich-939	147	13	and	and	CCONJ
biomedich-939	147	14	7	7	NUM
biomedich-939	147	15	have	have	VERB
biomedich-939	147	16	high	high	ADJ
biomedich-939	147	17	activity	activity	NOUN
biomedich-939	147	18	values	value	NOUN
biomedich-939	147	19	above	above	ADP
biomedich-939	147	20	3.0	3.0	NUM
biomedich-939	147	21	while	while	SCONJ
biomedich-939	147	22	compound	compound	NOUN
biomedich-939	147	23	5	5	NUM
biomedich-939	147	24	is	be	AUX
biomedich-939	147	25	well	well	ADV
biomedich-939	147	26	above	above	ADP
biomedich-939	147	27	5.0	5.0	NUM
biomedich-939	147	28	octanol	octanol	NOUN
biomedich-939	147	29	–	–	PUNCT
biomedich-939	147	30	water	water	NOUN
biomedich-939	147	31	partition	partition	NOUN
biomedich-939	147	32	coefficient	coefficient	NOUN
biomedich-939	147	33	value	value	NOUN
biomedich-939	147	34	indicating	indicate	VERB
biomedich-939	147	35	an	an	DET
biomedich-939	147	36	excellent	excellent	ADJ
biomedich-939	147	37	inhibitory	inhibitory	ADJ
biomedich-939	147	38	activity	activity	NOUN
biomedich-939	147	39	coupled	couple	VERB
biomedich-939	147	40	with	with	ADP
biomedich-939	147	41	strong	strong	ADJ
biomedich-939	147	42	chemical	chemical	NOUN
biomedich-939	147	43	reactivity	reactivity	NOUN
biomedich-939	147	44	.	.	PUNCT
biomedich-939	148	1	in	in	ADP
biomedich-939	148	2	the	the	DET
biomedich-939	148	3	work	work	NOUN
biomedich-939	148	4	of	of	ADP
biomedich-939	148	5	vlahovic	vlahovic	NOUN
biomedich-939	148	6	et	et	PROPN
biomedich-939	148	7	al	al	PROPN
biomedich-939	148	8	.	.	PROPN
biomedich-939	149	1	(	(	PUNCT
biomedich-939	149	2	2017	2017	NUM
biomedich-939	149	3	)	)	PUNCT
biomedich-939	149	4	,	,	PUNCT
biomedich-939	149	5	hydrophobic	hydrophobic	NOUN
biomedich-939	149	6	substances	substance	NOUN
biomedich-939	149	7	were	be	AUX
biomedich-939	149	8	reported	report	VERB
biomedich-939	149	9	to	to	PART
biomedich-939	149	10	have	have	VERB
biomedich-939	149	11	a	a	DET
biomedich-939	149	12	high	high	ADJ
biomedich-939	149	13	octanol	octanol	NOUN
biomedich-939	149	14	–	–	PUNCT
biomedich-939	149	15	water	water	NOUN
biomedich-939	149	16	partition	partition	NOUN
biomedich-939	149	17	coefficient	coefficient	NOUN
biomedich-939	149	18	distributed	distribute	VERB
biomedich-939	149	19	primarily	primarily	ADV
biomedich-939	149	20	in	in	ADP
biomedich-939	149	21	the	the	DET
biomedich-939	149	22	lipid	lipid	ADJ
biomedich-939	149	23	bilayers	bilayer	NOUN
biomedich-939	149	24	of	of	ADP
biomedich-939	149	25	cells	cell	NOUN
biomedich-939	149	26	while	while	SCONJ
biomedich-939	149	27	hydrophilic	hydrophilic	ADJ
biomedich-939	149	28	substances	substance	NOUN
biomedich-939	149	29	on	on	ADP
biomedich-939	149	30	the	the	DET
biomedich-939	149	31	other	other	ADJ
biomedich-939	149	32	hand	hand	NOUN
biomedich-939	149	33	have	have	VERB
biomedich-939	149	34	a	a	DET
biomedich-939	149	35	low	low	ADJ
biomedich-939	149	36	octanol	octanol	NOUN
biomedich-939	149	37	–	–	PUNCT
biomedich-939	149	38	water	water	NOUN
biomedich-939	149	39	partition	partition	NOUN
biomedich-939	149	40	coefficient	coefficient	NOUN
biomedich-939	149	41	and	and	CCONJ
biomedich-939	149	42	are	be	AUX
biomedich-939	149	43	distributed	distribute	VERB
biomedich-939	149	44	in	in	ADP
biomedich-939	149	45	blood	blood	NOUN
biomedich-939	149	46	plasma	plasma	NOUN
biomedich-939	149	47	.	.	PUNCT
biomedich-939	150	1	they	they	PRON
biomedich-939	150	2	also	also	ADV
biomedich-939	150	3	showed	show	VERB
biomedich-939	150	4	the	the	DET
biomedich-939	150	5	linear	linear	ADJ
biomedich-939	150	6	relationship	relationship	NOUN
biomedich-939	150	7	of	of	ADP
biomedich-939	150	8	the	the	DET
biomedich-939	150	9	octanol	octanol	NOUN
biomedich-939	150	10	–	–	PUNCT
biomedich-939	150	11	water	water	NOUN
biomedich-939	150	12	partition	partition	NOUN
biomedich-939	150	13	coefficient	coefficient	NOUN
biomedich-939	150	14	with	with	ADP
biomedich-939	150	15	log	log	PROPN
biomedich-939	150	16	p	p	NOUN
biomedich-939	150	17	which	which	PRON
biomedich-939	150	18	explains	explain	VERB
biomedich-939	150	19	the	the	DET
biomedich-939	150	20	high	high	ADJ
biomedich-939	150	21	milogp	milogp	NOUN
biomedich-939	150	22	values	value	NOUN
biomedich-939	150	23	obtained	obtain	VERB
biomedich-939	150	24	for	for	ADP
biomedich-939	150	25	compound	compound	NOUN
biomedich-939	150	26	5	5	NUM
biomedich-939	150	27	with	with	ADP
biomedich-939	150	28	a	a	DET
biomedich-939	150	29	value	value	NOUN
biomedich-939	150	30	of	of	ADP
biomedich-939	150	31	5.59	5.59	NUM
biomedich-939	150	32	as	as	SCONJ
biomedich-939	150	33	shown	show	VERB
biomedich-939	150	34	in	in	ADP
biomedich-939	150	35	table	table	NOUN
biomedich-939	150	36	3	3	NUM
biomedich-939	150	37	.	.	PUNCT
biomedich-939	151	1	this	this	PRON
biomedich-939	151	2	shows	show	VERB
biomedich-939	151	3	the	the	DET
biomedich-939	151	4	synthesised	synthesise	VERB
biomedich-939	151	5	2phenoxyquinolines	2phenoxyquinolines	PROPN
biomedich-939	151	6	to	to	PART
biomedich-939	151	7	be	be	AUX
biomedich-939	151	8	hydrophobic	hydrophobic	NOUN
biomedich-939	151	9	hence	hence	ADV
biomedich-939	151	10	would	would	AUX
biomedich-939	151	11	easily	easily	ADV
biomedich-939	151	12	distribute	distribute	VERB
biomedich-939	151	13	in	in	ADP
biomedich-939	151	14	the	the	DET
biomedich-939	151	15	lipid	lipid	NOUN
biomedich-939	151	16	bilayers	bilayer	NOUN
biomedich-939	151	17	.	.	PUNCT
biomedich-939	152	1	compound	compound	NOUN
biomedich-939	152	2	8	8	NUM
biomedich-939	152	3	with	with	ADP
biomedich-939	152	4	the	the	DET
biomedich-939	152	5	least	least	ADJ
biomedich-939	152	6	value	value	NOUN
biomedich-939	152	7	milogp	milogp	NOUN
biomedich-939	152	8	value	value	NOUN
biomedich-939	152	9	of	of	ADP
biomedich-939	152	10	1.94	1.94	NUM
biomedich-939	152	11	is	be	AUX
biomedich-939	152	12	more	more	ADV
biomedich-939	152	13	hydrophilic	hydrophilic	ADJ
biomedich-939	152	14	than	than	ADP
biomedich-939	152	15	others	other	NOUN
biomedich-939	152	16	and	and	CCONJ
biomedich-939	152	17	will	will	AUX
biomedich-939	152	18	be	be	AUX
biomedich-939	152	19	more	more	ADV
biomedich-939	152	20	readily	readily	ADV
biomedich-939	152	21	distributed	distribute	VERB
biomedich-939	152	22	in	in	ADP
biomedich-939	152	23	blood	blood	NOUN
biomedich-939	152	24	plasma	plasma	NOUN
biomedich-939	152	25	.	.	PUNCT
biomedich-939	153	1	drug	drug	NOUN
biomedich-939	153	2	likeness	likeness	NOUN
biomedich-939	153	3	and	and	CCONJ
biomedich-939	153	4	bioactivity	bioactivity	NOUN
biomedich-939	153	5	score	score	NOUN
biomedich-939	153	6	medicinal	medicinal	ADJ
biomedich-939	153	7	chemists	chemist	NOUN
biomedich-939	153	8	use	use	VERB
biomedich-939	153	9	drug	drug	NOUN
biomedich-939	153	10	-	-	PUNCT
biomedich-939	153	11	likeness	likeness	NOUN
biomedich-939	153	12	as	as	ADP
biomedich-939	153	13	the	the	DET
biomedich-939	153	14	essential	essential	ADJ
biomedich-939	153	15	guide	guide	NOUN
biomedich-939	153	16	via	via	ADP
biomedich-939	153	17	hit	hit	NOUN
biomedich-939	153	18	-	-	PUNCT
biomedich-939	153	19	to	to	ADP
biomedich-939	153	20	-	-	PUNCT
biomedich-939	153	21	lead	lead	VERB
biomedich-939	153	22	optimization	optimization	NOUN
biomedich-939	153	23	for	for	ADP
biomedich-939	153	24	drug	drug	NOUN
biomedich-939	153	25	discovery	discovery	NOUN
biomedich-939	153	26	(	(	PUNCT
biomedich-939	153	27	sagaama	sagaama	NOUN
biomedich-939	153	28	&	&	CCONJ
biomedich-939	153	29	issaoui	issaoui	NOUN
biomedich-939	153	30	,	,	PUNCT
biomedich-939	153	31	2020	2020	NUM
biomedich-939	153	32	,	,	PUNCT
biomedich-939	153	33	maldonado	maldonado	PROPN
biomedich-939	153	34	et	et	PROPN
biomedich-939	153	35	al	al	PROPN
biomedich-939	153	36	.	.	PROPN
biomedich-939	153	37	,	,	PUNCT
biomedich-939	153	38	2021	2021	NUM
biomedich-939	153	39	)	)	PUNCT
biomedich-939	153	40	.	.	PUNCT
biomedich-939	154	1	pharmacokinetic	pharmacokinetic	ADJ
biomedich-939	154	2	properties	property	NOUN
biomedich-939	154	3	detailed	detail	VERB
biomedich-939	154	4	in	in	ADP
biomedich-939	154	5	adme	adme	NOUN
biomedich-939	154	6	parameters	parameter	NOUN
biomedich-939	154	7	are	be	AUX
biomedich-939	154	8	also	also	ADV
biomedich-939	154	9	strongly	strongly	ADV
biomedich-939	154	10	affected	affect	VERB
biomedich-939	154	11	by	by	ADP
biomedich-939	154	12	physicochemical	physicochemical	ADJ
biomedich-939	154	13	properties	property	NOUN
biomedich-939	154	14	(	(	PUNCT
biomedich-939	154	15	kumar	kumar	PROPN
biomedich-939	154	16	et	et	PROPN
biomedich-939	154	17	al	al	PROPN
biomedich-939	154	18	.	.	PROPN
biomedich-939	154	19	,	,	PUNCT
biomedich-939	154	20	2017	2017	NUM
biomedich-939	154	21	;	;	PUNCT
biomedich-939	154	22	zheng	zheng	PROPN
biomedich-939	154	23	et	et	PROPN
biomedich-939	154	24	al	al	PROPN
biomedich-939	154	25	.	.	PROPN
biomedich-939	154	26	,	,	PUNCT
biomedich-939	154	27	2013	2013	NUM
biomedich-939	154	28	)	)	PUNCT
biomedich-939	154	29	.	.	PUNCT
biomedich-939	155	1	since	since	SCONJ
biomedich-939	155	2	drug	drug	NOUN
biomedich-939	155	3	-	-	PUNCT
biomedich-939	155	4	like	like	ADJ
biomedich-939	155	5	molecules	molecule	NOUN
biomedich-939	155	6	must	must	AUX
biomedich-939	155	7	be	be	AUX
biomedich-939	155	8	soluble	soluble	ADJ
biomedich-939	155	9	in	in	ADP
biomedich-939	155	10	water	water	NOUN
biomedich-939	155	11	as	as	ADV
biomedich-939	155	12	well	well	ADV
biomedich-939	155	13	as	as	ADP
biomedich-939	155	14	fat	fat	ADJ
biomedich-939	155	15	,	,	PUNCT
biomedich-939	155	16	it	it	PRON
biomedich-939	155	17	is	be	AUX
biomedich-939	155	18	therefore	therefore	ADV
biomedich-939	155	19	necessary	necessary	ADJ
biomedich-939	155	20	that	that	SCONJ
biomedich-939	155	21	an	an	DET
biomedich-939	155	22	orally	orally	ADV
biomedich-939	155	23	administered	administer	VERB
biomedich-939	155	24	drug	drug	NOUN
biomedich-939	155	25	passes	pass	VERB
biomedich-939	155	26	through	through	ADP
biomedich-939	155	27	the	the	DET
biomedich-939	155	28	intestinal	intestinal	ADJ
biomedich-939	155	29	lining	lining	NOUN
biomedich-939	155	30	into	into	ADP
biomedich-939	155	31	the	the	DET
biomedich-939	155	32	bloodstream	bloodstream	NOUN
biomedich-939	155	33	and	and	CCONJ
biomedich-939	155	34	is	be	AUX
biomedich-939	155	35	carried	carry	VERB
biomedich-939	155	36	to	to	ADP
biomedich-939	155	37	the	the	DET
biomedich-939	155	38	target	target	NOUN
biomedich-939	155	39	immediately	immediately	ADV
biomedich-939	155	40	after	after	ADP
biomedich-939	155	41	ingestion	ingestion	NOUN
biomedich-939	155	42	,	,	PUNCT
biomedich-939	155	43	penetrating	penetrate	VERB
biomedich-939	155	44	the	the	DET
biomedich-939	155	45	lipid	lipid	NOUN
biomedich-939	155	46	-	-	PUNCT
biomedich-939	155	47	based	base	VERB
biomedich-939	155	48	cell	cell	NOUN
biomedich-939	155	49	membrane	membrane	NOUN
biomedich-939	155	50	to	to	PART
biomedich-939	155	51	get	get	VERB
biomedich-939	155	52	into	into	ADP
biomedich-939	155	53	the	the	DET
biomedich-939	155	54	target	target	NOUN
biomedich-939	155	55	cell	cell	NOUN
biomedich-939	155	56	(	(	PUNCT
biomedich-939	155	57	kumar	kumar	PROPN
biomedich-939	155	58	et	et	PROPN
biomedich-939	155	59	al	al	PROPN
biomedich-939	155	60	.	.	PROPN
biomedich-939	155	61	,	,	PUNCT
biomedich-939	155	62	2017	2017	NUM
biomedich-939	155	63	)	)	PUNCT
biomedich-939	155	64	.	.	PUNCT
biomedich-939	156	1	increased	increase	VERB
biomedich-939	156	2	hydrogen	hydrogen	NOUN
biomedich-939	156	3	bonds	bond	NOUN
biomedich-939	156	4	leads	lead	VERB
biomedich-939	156	5	to	to	ADP
biomedich-939	156	6	increased	increase	VERB
biomedich-939	156	7	aqueous	aqueous	ADJ
biomedich-939	156	8	solubility	solubility	NOUN
biomedich-939	156	9	making	make	VERB
biomedich-939	156	10	the	the	DET
biomedich-939	156	11	molecule	molecule	NOUN
biomedich-939	156	12	less	less	ADV
biomedich-939	156	13	hydrophobic	hydrophobic	NOUN
biomedich-939	156	14	since	since	SCONJ
biomedich-939	156	15	it	it	PRON
biomedich-939	156	16	enables	enable	VERB
biomedich-939	156	17	the	the	DET
biomedich-939	156	18	molecule	molecule	NOUN
biomedich-939	156	19	to	to	PART
biomedich-939	156	20	permeate	permeate	VERB
biomedich-939	156	21	into	into	ADP
biomedich-939	156	22	and	and	CCONJ
biomedich-939	156	23	through	through	ADP
biomedich-939	156	24	the	the	DET
biomedich-939	156	25	lipid	lipid	ADJ
biomedich-939	156	26	bilayer	bilayer	NOUN
biomedich-939	156	27	membrane	membrane	NOUN
biomedich-939	156	28	(	(	PUNCT
biomedich-939	156	29	di	di	X
biomedich-939	156	30	&	&	CCONJ
biomedich-939	156	31	kerns	kerns	PROPN
biomedich-939	156	32	,	,	PUNCT
biomedich-939	156	33	2015	2015	NUM
biomedich-939	156	34	)	)	PUNCT
biomedich-939	156	35	.	.	PUNCT
biomedich-939	157	1	as	as	SCONJ
biomedich-939	157	2	reported	report	VERB
biomedich-939	157	3	by	by	ADP
biomedich-939	157	4	veber	veber	PROPN
biomedich-939	157	5	and	and	CCONJ
biomedich-939	157	6	co	co	NOUN
biomedich-939	157	7	-	-	NOUN
biomedich-939	157	8	workers	worker	NOUN
biomedich-939	157	9	,	,	PUNCT
biomedich-939	157	10	drug	drug	NOUN
biomedich-939	157	11	candidates	candidate	NOUN
biomedich-939	157	12	will	will	AUX
biomedich-939	157	13	have	have	VERB
biomedich-939	157	14	a	a	DET
biomedich-939	157	15	high	high	ADJ
biomedich-939	157	16	probability	probability	NOUN
biomedich-939	157	17	of	of	ADP
biomedich-939	157	18	good	good	ADJ
biomedich-939	157	19	oral	oral	ADJ
biomedich-939	157	20	bioavailability	bioavailability	NOUN
biomedich-939	157	21	if	if	SCONJ
biomedich-939	157	22	they	they	PRON
biomedich-939	157	23	meet	meet	VERB
biomedich-939	157	24	criteria	criterion	NOUN
biomedich-939	157	25	such	such	ADJ
biomedich-939	157	26	as	as	ADP
biomedich-939	157	27	:	:	PUNCT
biomedich-939	157	28	total	total	ADJ
biomedich-939	157	29	polar	polar	ADJ
biomedich-939	157	30	surface	surface	NOUN
biomedich-939	157	31	area	area	NOUN
biomedich-939	157	32	(	(	PUNCT
biomedich-939	157	33	tpsa	tpsa	NOUN
biomedich-939	157	34	)	)	PUNCT
biomedich-939	157	35	≤	≤	NUM
biomedich-939	157	36	140	140	NUM
biomedich-939	157	37	å2	å2	NOUN
biomedich-939	157	38	and	and	CCONJ
biomedich-939	157	39	if	if	SCONJ
biomedich-939	157	40	the	the	DET
biomedich-939	157	41	number	number	NOUN
biomedich-939	157	42	of	of	ADP
biomedich-939	157	43	rotatable	rotatable	ADJ
biomedich-939	157	44	bonds	bond	NOUN
biomedich-939	157	45	(	(	PUNCT
biomedich-939	157	46	nrotb	nrotb	NOUN
biomedich-939	157	47	)	)	PUNCT
biomedich-939	157	48	≤	≤	NOUN
biomedich-939	157	49	10	10	NUM
biomedich-939	157	50	(	(	PUNCT
biomedich-939	157	51	veber	veber	PROPN
biomedich-939	157	52	et	et	PROPN
biomedich-939	157	53	al	al	PROPN
biomedich-939	157	54	.	.	PROPN
biomedich-939	157	55	,	,	PUNCT
biomedich-939	157	56	2002	2002	NUM
biomedich-939	157	57	)	)	PUNCT
biomedich-939	157	58	.	.	PUNCT
biomedich-939	158	1	amazingly	amazingly	ADV
biomedich-939	158	2	,	,	PUNCT
biomedich-939	158	3	all	all	DET
biomedich-939	158	4	2phenoxyquinolinequinoline-3	2phenoxyquinolinequinoline-3	NUM
biomedich-939	158	5	-	-	PUNCT
biomedich-939	158	6	carbaldehydes	carbaldehyde	NOUN
biomedich-939	158	7	investigated	investigate	VERB
biomedich-939	158	8	in	in	ADP
biomedich-939	158	9	this	this	DET
biomedich-939	158	10	study	study	NOUN
biomedich-939	158	11	fulfil	fulfil	NOUN
biomedich-939	158	12	all	all	DET
biomedich-939	158	13	these	these	DET
biomedich-939	158	14	criteria	criterion	NOUN
biomedich-939	158	15	.	.	PUNCT
biomedich-939	159	1	while	while	SCONJ
biomedich-939	159	2	the	the	DET
biomedich-939	159	3	monoacetoxylated	monoacetoxylated	ADJ
biomedich-939	159	4	1	1	NUM
biomedich-939	159	5	-	-	SYM
biomedich-939	159	6	4	4	NUM
biomedich-939	159	7	and	and	CCONJ
biomedich-939	159	8	benzoylated	benzoylate	VERB
biomedich-939	159	9	5	5	NUM
biomedich-939	159	10	2phenoxyquinolines	2phenoxyquinolines	PROPN
biomedich-939	159	11	have	have	VERB
biomedich-939	159	12	excellent	excellent	ADJ
biomedich-939	159	13	total	total	ADJ
biomedich-939	159	14	polar	polar	ADJ
biomedich-939	159	15	surface	surface	NOUN
biomedich-939	159	16	area	area	NOUN
biomedich-939	159	17	(	(	PUNCT
biomedich-939	159	18	65	65	NUM
biomedich-939	159	19	-	-	SYM
biomedich-939	159	20	74	74	NUM
biomedich-939	159	21	a2	a2	PROPN
biomedich-939	159	22	)	)	PUNCT
biomedich-939	159	23	,	,	PUNCT
biomedich-939	159	24	the	the	DET
biomedich-939	159	25	di	di	NOUN
biomedich-939	159	26	-	-	ADJ
biomedich-939	159	27	acetoxylated	acetoxylate	VERB
biomedich-939	159	28	groups	group	NOUN
biomedich-939	159	29	have	have	VERB
biomedich-939	159	30	much	much	ADV
biomedich-939	159	31	higher	high	ADJ
biomedich-939	159	32	values	value	NOUN
biomedich-939	159	33	ranging	range	VERB
biomedich-939	159	34	from	from	ADP
biomedich-939	159	35	91	91	NUM
biomedich-939	159	36	-	-	PUNCT
biomedich-939	159	37	101	101	NUM
biomedich-939	159	38	a2	a2	PROPN
biomedich-939	159	39	)	)	PUNCT
biomedich-939	159	40	as	as	SCONJ
biomedich-939	159	41	shown	show	VERB
biomedich-939	159	42	in	in	ADP
biomedich-939	159	43	table	table	NOUN
biomedich-939	159	44	3	3	NUM
biomedich-939	159	45	.	.	PUNCT
biomedich-939	159	46	figure	figure	NOUN
biomedich-939	159	47	9	9	NUM
biomedich-939	159	48	.	.	PUNCT
biomedich-939	159	49	relationship	relationship	NOUN
biomedich-939	159	50	between	between	ADP
biomedich-939	159	51	volume	volume	NOUN
biomedich-939	159	52	and	and	CCONJ
biomedich-939	159	53	molecular	molecular	ADJ
biomedich-939	159	54	weight	weight	NOUN
biomedich-939	159	55	of	of	ADP
biomedich-939	159	56	synthesised	synthesise	VERB
biomedich-939	159	57	2	2	NUM
biomedich-939	159	58	-	-	PUNCT
biomedich-939	159	59	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	159	60	.	.	PUNCT
biomedich-939	160	1	1	1	NUM
biomedich-939	160	2	2	2	NUM
biomedich-939	160	3	3	3	NUM
biomedich-939	160	4	4	4	NUM
biomedich-939	160	5	5	5	NUM
biomedich-939	160	6	6	6	NUM
biomedich-939	160	7	7	7	NUM
biomedich-939	160	8	8	8	NUM
biomedich-939	160	9	260	260	NUM
biomedich-939	160	10	270	270	NUM
biomedich-939	160	11	280	280	NUM
biomedich-939	160	12	290	290	NUM
biomedich-939	160	13	300	300	NUM
biomedich-939	160	14	310	310	NUM
biomedich-939	160	15	320	320	NUM
biomedich-939	160	16	330	330	NUM
biomedich-939	160	17	340	340	NUM
biomedich-939	160	18	350	350	NUM
biomedich-939	160	19	360	360	NUM
biomedich-939	160	20	307,31	307,31	NUM
biomedich-939	160	21	321,33	321,33	NUM
biomedich-939	160	22	339,32	339,32	NUM
biomedich-939	160	23	321,33	321,33	NUM
biomedich-939	160	24	367,4	367,4	PROPN
biomedich-939	160	25	365,34	365,34	NUM
biomedich-939	160	26	409,39	409,39	NOUN
biomedich-939	160	27	397,36	397,36	NUM
biomedich-939	160	28	v	v	ADP
biomedich-939	160	29	o	o	X
biomedich-939	160	30	lu	lu	NOUN
biomedich-939	160	31	m	m	VERB
biomedich-939	160	32	e	e	NOUN
biomedich-939	160	33	molecular	molecular	ADJ
biomedich-939	160	34	weight	weight	NOUN
biomedich-939	160	35	,	,	PUNCT
biomedich-939	160	36	mw	mw	X
biomedich-939	160	37	(	(	PUNCT
biomedich-939	160	38	g	g	NOUN
biomedich-939	160	39	/	/	SYM
biomedich-939	160	40	mol	mol	NOUN
biomedich-939	160	41	)	)	PUNCT
biomedich-939	160	42	y	y	PROPN
biomedich-939	160	43	=	=	PUNCT
biomedich-939	160	44	0.7901x	0.7901x	PROPN
biomedich-939	161	1	+	+	NUM
biomedich-939	161	2	27.684	27.684	NUM
biomedich-939	161	3	r2	r2	NOUN
biomedich-939	161	4	=	=	NOUN
biomedich-939	161	5	0.9527	0.9527	NUM
biomedich-939	161	6	852	852	NUM
biomedich-939	161	7	biology	biology	NOUN
biomedich-939	161	8	,	,	PUNCT
biomedich-939	161	9	medicine	medicine	NOUN
biomedich-939	161	10	,	,	PUNCT
biomedich-939	161	11	&	&	CCONJ
biomedich-939	161	12	natural	natural	ADJ
biomedich-939	161	13	product	product	NOUN
biomedich-939	161	14	chemistry	chemistry	NOUN
biomedich-939	161	15	14	14	NUM
biomedich-939	161	16	(	(	PUNCT
biomedich-939	161	17	2	2	NUM
biomedich-939	161	18	)	)	PUNCT
biomedich-939	161	19	,	,	PUNCT
biomedich-939	161	20	2025	2025	NUM
biomedich-939	161	21	:	:	PUNCT
biomedich-939	161	22	843	843	NUM
biomedich-939	161	23	-	-	SYM
biomedich-939	161	24	856	856	NUM
biomedich-939	161	25	it	it	PRON
biomedich-939	161	26	is	be	AUX
biomedich-939	161	27	noteworthy	noteworthy	ADJ
biomedich-939	161	28	to	to	PART
biomedich-939	161	29	express	express	VERB
biomedich-939	161	30	the	the	DET
biomedich-939	161	31	super	super	ADJ
biomedich-939	161	32	permeability	permeability	NOUN
biomedich-939	161	33	of	of	ADP
biomedich-939	161	34	compound	compound	NOUN
biomedich-939	161	35	5	5	NUM
biomedich-939	161	36	(	(	PUNCT
biomedich-939	161	37	with	with	ADP
biomedich-939	161	38	a	a	DET
biomedich-939	161	39	tpsa	tpsa	NOUN
biomedich-939	161	40	value	value	NOUN
biomedich-939	161	41	of	of	ADP
biomedich-939	161	42	56.27	56.27	NUM
biomedich-939	161	43	a2	a2	NOUN
biomedich-939	161	44	)	)	PUNCT
biomedich-939	161	45	in	in	ADP
biomedich-939	161	46	lipid	lipid	ADJ
biomedich-939	161	47	membranes	membrane	NOUN
biomedich-939	161	48	.	.	PUNCT
biomedich-939	162	1	the	the	DET
biomedich-939	162	2	lipinski	lipinski	PROPN
biomedich-939	162	3	’s	’s	PART
biomedich-939	162	4	rule	rule	NOUN
biomedich-939	162	5	of	of	ADP
biomedich-939	162	6	5	5	NUM
biomedich-939	162	7	states	state	NOUN
biomedich-939	162	8	that	that	SCONJ
biomedich-939	162	9	for	for	SCONJ
biomedich-939	162	10	a	a	DET
biomedich-939	162	11	drug	drug	NOUN
biomedich-939	162	12	molecule	molecule	NOUN
biomedich-939	162	13	to	to	PART
biomedich-939	162	14	be	be	AUX
biomedich-939	162	15	orally	orally	ADV
biomedich-939	162	16	active	active	ADJ
biomedich-939	162	17	it	it	PRON
biomedich-939	162	18	should	should	AUX
biomedich-939	162	19	obey	obey	VERB
biomedich-939	162	20	important	important	ADJ
biomedich-939	162	21	rules	rule	NOUN
biomedich-939	162	22	such	such	ADJ
biomedich-939	162	23	as	as	ADP
biomedich-939	162	24	number	number	NOUN
biomedich-939	162	25	of	of	ADP
biomedich-939	162	26	hydrogen	hydrogen	NOUN
biomedich-939	162	27	bond	bond	NOUN
biomedich-939	162	28	donors	donor	NOUN
biomedich-939	162	29	(	(	PUNCT
biomedich-939	162	30	nohnh	nohnh	NOUN
biomedich-939	162	31	)	)	PUNCT
biomedich-939	162	32	≤5	≤5	PROPN
biomedich-939	162	33	,	,	PUNCT
biomedich-939	162	34	number	number	NOUN
biomedich-939	162	35	of	of	ADP
biomedich-939	162	36	hydrogen	hydrogen	NOUN
biomedich-939	162	37	bond	bond	NOUN
biomedich-939	162	38	acceptors	acceptor	NOUN
biomedich-939	162	39	(	(	PUNCT
biomedich-939	162	40	non	non	ADJ
biomedich-939	162	41	)	)	PUNCT
biomedich-939	162	42	≤	≤	ADV
biomedich-939	162	43	10	10	NUM
biomedich-939	162	44	,	,	PUNCT
biomedich-939	162	45	molecular	molecular	ADJ
biomedich-939	162	46	weight	weight	NOUN
biomedich-939	162	47	(	(	PUNCT
biomedich-939	162	48	mw	mw	NOUN
biomedich-939	162	49	)	)	PUNCT
biomedich-939	162	50	≤	≤	NOUN
biomedich-939	162	51	500	500	NUM
biomedich-939	162	52	,	,	PUNCT
biomedich-939	162	53	partition	partition	NOUN
biomedich-939	162	54	coefficient	coefficient	NOUN
biomedich-939	162	55	(	(	PUNCT
biomedich-939	162	56	milogp	milogp	NOUN
biomedich-939	162	57	)	)	PUNCT
biomedich-939	162	58	≤	≤	NOUN
biomedich-939	162	59	5	5	NUM
biomedich-939	162	60	and	and	CCONJ
biomedich-939	162	61	number	number	NOUN
biomedich-939	162	62	of	of	ADP
biomedich-939	162	63	violations	violation	NOUN
biomedich-939	162	64	(	(	PUNCT
biomedich-939	162	65	nviolations	nviolation	NOUN
biomedich-939	162	66	)	)	PUNCT
biomedich-939	162	67	≤	≤	NUM
biomedich-939	162	68	2	2	NUM
biomedich-939	162	69	(	(	PUNCT
biomedich-939	162	70	maurya	maurya	PROPN
biomedich-939	162	71	et	et	PROPN
biomedich-939	162	72	al	al	PROPN
biomedich-939	162	73	.	.	PROPN
biomedich-939	162	74	,	,	PUNCT
biomedich-939	162	75	2020	2020	NUM
biomedich-939	162	76	)	)	PUNCT
biomedich-939	162	77	.	.	PUNCT
biomedich-939	163	1	interestingly	interestingly	ADV
biomedich-939	163	2	,	,	PUNCT
biomedich-939	163	3	all	all	DET
biomedich-939	163	4	the	the	DET
biomedich-939	163	5	2phenoxyquinoline-3	2phenoxyquinoline-3	NUM
biomedich-939	163	6	-	-	PUNCT
biomedich-939	163	7	carbaldehydes	carbaldehyde	NOUN
biomedich-939	163	8	comply	comply	VERB
biomedich-939	163	9	with	with	ADP
biomedich-939	163	10	the	the	DET
biomedich-939	163	11	lipinski	lipinski	PROPN
biomedich-939	163	12	rule	rule	NOUN
biomedich-939	163	13	of	of	ADP
biomedich-939	163	14	5	5	NUM
biomedich-939	163	15	(	(	PUNCT
biomedich-939	163	16	table	table	NOUN
biomedich-939	163	17	3	3	NUM
biomedich-939	163	18	)	)	PUNCT
biomedich-939	163	19	,	,	PUNCT
biomedich-939	163	20	testifying	testify	VERB
biomedich-939	163	21	to	to	ADP
biomedich-939	163	22	their	their	PRON
biomedich-939	163	23	oral	oral	ADJ
biomedich-939	163	24	bioavailabilities	bioavailabilitie	NOUN
biomedich-939	163	25	as	as	ADP
biomedich-939	163	26	potential	potential	ADJ
biomedich-939	163	27	drug	drug	NOUN
biomedich-939	163	28	molecules	molecule	NOUN
biomedich-939	163	29	.	.	PUNCT
biomedich-939	164	1	in	in	ADP
biomedich-939	164	2	compliance	compliance	NOUN
biomedich-939	164	3	,	,	PUNCT
biomedich-939	164	4	the	the	DET
biomedich-939	164	5	molecular	molecular	ADJ
biomedich-939	164	6	weight	weight	NOUN
biomedich-939	164	7	of	of	ADP
biomedich-939	164	8	the	the	DET
biomedich-939	164	9	compounds	compound	NOUN
biomedich-939	164	10	is	be	AUX
biomedich-939	164	11	directly	directly	ADV
biomedich-939	164	12	proportional	proportional	ADJ
biomedich-939	164	13	to	to	ADP
biomedich-939	164	14	the	the	DET
biomedich-939	164	15	volume	volume	NOUN
biomedich-939	164	16	of	of	ADP
biomedich-939	164	17	the	the	DET
biomedich-939	164	18	compounds	compound	NOUN
biomedich-939	164	19	(	(	PUNCT
biomedich-939	164	20	table	table	NOUN
biomedich-939	164	21	3	3	NUM
biomedich-939	164	22	,	,	PUNCT
biomedich-939	164	23	fig	fig	NOUN
biomedich-939	164	24	.	.	PUNCT
biomedich-939	165	1	9	9	NUM
biomedich-939	165	2	)	)	PUNCT
biomedich-939	165	3	which	which	PRON
biomedich-939	165	4	confirms	confirm	VERB
biomedich-939	165	5	their	their	PRON
biomedich-939	165	6	correlation	correlation	NOUN
biomedich-939	165	7	with	with	ADP
biomedich-939	165	8	the	the	DET
biomedich-939	165	9	pearson	pearson	PROPN
biomedich-939	165	10	correlation	correlation	NOUN
biomedich-939	165	11	co	co	ADJ
biomedich-939	165	12	-	-	ADJ
biomedich-939	165	13	efficient	efficient	ADJ
biomedich-939	165	14	(	(	PUNCT
biomedich-939	165	15	r	r	NOUN
biomedich-939	165	16	)	)	PUNCT
biomedich-939	165	17	of	of	ADP
biomedich-939	165	18	0.97	0.97	NUM
biomedich-939	165	19	and	and	CCONJ
biomedich-939	165	20	r2	r2	NOUN
biomedich-939	165	21	value	value	NOUN
biomedich-939	165	22	of	of	ADP
biomedich-939	165	23	0.94	0.94	NUM
biomedich-939	165	24	which	which	PRON
biomedich-939	165	25	states	state	VERB
biomedich-939	165	26	that	that	SCONJ
biomedich-939	165	27	for	for	ADP
biomedich-939	165	28	an	an	DET
biomedich-939	165	29	average	average	ADJ
biomedich-939	165	30	organic	organic	ADJ
biomedich-939	165	31	molecule	molecule	NOUN
biomedich-939	165	32	,	,	PUNCT
biomedich-939	165	33	if	if	SCONJ
biomedich-939	165	34	the	the	DET
biomedich-939	165	35	bioactivity	bioactivity	NOUN
biomedich-939	165	36	score	score	NOUN
biomedich-939	165	37	is	be	AUX
biomedich-939	165	38	more	more	ADJ
biomedich-939	165	39	than	than	ADP
biomedich-939	165	40	0	0	NUM
biomedich-939	165	41	then	then	ADV
biomedich-939	165	42	it	it	PRON
biomedich-939	165	43	is	be	AUX
biomedich-939	165	44	active	active	ADJ
biomedich-939	165	45	,	,	PUNCT
biomedich-939	165	46	a	a	DET
biomedich-939	165	47	score	score	NOUN
biomedich-939	165	48	ranging	range	VERB
biomedich-939	165	49	from	from	ADP
biomedich-939	165	50	-0.50	-0.50	NUM
biomedich-939	165	51	to	to	ADP
biomedich-939	165	52	0.0	0.0	NUM
biomedich-939	165	53	indicates	indicate	VERB
biomedich-939	165	54	moderately	moderately	ADV
biomedich-939	165	55	active	active	ADJ
biomedich-939	165	56	and	and	CCONJ
biomedich-939	165	57	a	a	DET
biomedich-939	165	58	score	score	NOUN
biomedich-939	165	59	of	of	ADP
biomedich-939	165	60	less	less	ADJ
biomedich-939	165	61	than	than	ADP
biomedich-939	165	62	-0.50	-0.50	PROPN
biomedich-939	165	63	denotes	denotes	PROPN
biomedich-939	165	64	inactivity	inactivity	NOUN
biomedich-939	165	65	(	(	PUNCT
biomedich-939	165	66	figure	figure	NOUN
biomedich-939	165	67	10	10	NUM
biomedich-939	165	68	)	)	PUNCT
biomedich-939	165	69	(	(	PUNCT
biomedich-939	165	70	alodeani	alodeani	PROPN
biomedich-939	165	71	et	et	PROPN
biomedich-939	165	72	al	al	PROPN
biomedich-939	165	73	.	.	PROPN
biomedich-939	165	74	,	,	PUNCT
biomedich-939	165	75	2015	2015	NUM
biomedich-939	165	76	;	;	PUNCT
biomedich-939	165	77	akintemi	akintemi	PROPN
biomedich-939	165	78	et	et	PROPN
biomedich-939	165	79	al	al	PROPN
biomedich-939	165	80	.	.	PROPN
biomedich-939	165	81	,	,	PUNCT
biomedich-939	165	82	2022	2022	NUM
biomedich-939	165	83	)	)	PUNCT
biomedich-939	165	84	.	.	PUNCT
biomedich-939	166	1	to	to	PART
biomedich-939	166	2	further	far	ADV
biomedich-939	166	3	confirm	confirm	VERB
biomedich-939	166	4	the	the	DET
biomedich-939	166	5	correlation	correlation	NOUN
biomedich-939	166	6	by	by	ADP
biomedich-939	166	7	the	the	DET
biomedich-939	166	8	pearson	pearson	PROPN
biomedich-939	166	9	correlation	correlation	NOUN
biomedich-939	166	10	coefficient	coefficient	NOUN
biomedich-939	166	11	,	,	PUNCT
biomedich-939	166	12	the	the	DET
biomedich-939	166	13	bioavailability	bioavailability	NOUN
biomedich-939	166	14	of	of	ADP
biomedich-939	166	15	the	the	DET
biomedich-939	166	16	investigated	investigate	VERB
biomedich-939	166	17	compounds	compound	NOUN
biomedich-939	166	18	as	as	ADP
biomedich-939	166	19	inhibitors/	inhibitors/	NUM
biomedich-939	166	20	substrates	substrate	NOUN
biomedich-939	166	21	were	be	AUX
biomedich-939	166	22	carried	carry	VERB
biomedich-939	166	23	out	out	ADP
biomedich-939	166	24	using	use	VERB
biomedich-939	166	25	profile	profile	NOUN
biomedich-939	166	26	depicting	depict	VERB
biomedich-939	166	27	bioactivity	bioactivity	NOUN
biomedich-939	166	28	score	score	NOUN
biomedich-939	166	29	as	as	SCONJ
biomedich-939	166	30	presented	present	VERB
biomedich-939	166	31	in	in	ADP
biomedich-939	166	32	figure	figure	NOUN
biomedich-939	166	33	10	10	NUM
biomedich-939	166	34	.	.	PUNCT
biomedich-939	167	1	it	it	PRON
biomedich-939	167	2	is	be	AUX
biomedich-939	167	3	obvious	obvious	ADJ
biomedich-939	167	4	that	that	SCONJ
biomedich-939	167	5	compound	compound	NOUN
biomedich-939	167	6	5	5	NUM
biomedich-939	167	7	exhibit	exhibit	VERB
biomedich-939	167	8	excellent	excellent	ADJ
biomedich-939	167	9	activity	activity	NOUN
biomedich-939	167	10	as	as	ADP
biomedich-939	167	11	kinase	kinase	NOUN
biomedich-939	167	12	inhibitors	inhibitor	NOUN
biomedich-939	167	13	,	,	PUNCT
biomedich-939	167	14	nuclear	nuclear	ADJ
biomedich-939	167	15	receptor	receptor	NOUN
biomedich-939	167	16	compounds	compound	NOUN
biomedich-939	167	17	and	and	CCONJ
biomedich-939	167	18	enzyme	enzyme	NOUN
biomedich-939	167	19	inhibitors	inhibitor	NOUN
biomedich-939	167	20	while	while	SCONJ
biomedich-939	167	21	3	3	NUM
biomedich-939	167	22	shows	show	VERB
biomedich-939	167	23	good	good	ADJ
biomedich-939	167	24	activity	activity	NOUN
biomedich-939	167	25	as	as	ADP
biomedich-939	167	26	enzyme	enzyme	NOUN
biomedich-939	167	27	inhibitor	inhibitor	NOUN
biomedich-939	167	28	and	and	CCONJ
biomedich-939	167	29	nuclear	nuclear	ADJ
biomedich-939	167	30	receptor	receptor	NOUN
biomedich-939	167	31	compound	compound	NOUN
biomedich-939	167	32	.	.	PUNCT
biomedich-939	168	1	compounds	compound	VERB
biomedich-939	168	2	3	3	NUM
biomedich-939	168	3	and	and	CCONJ
biomedich-939	168	4	4	4	NUM
biomedich-939	168	5	exhibit	exhibit	VERB
biomedich-939	168	6	much	much	ADV
biomedich-939	168	7	lower	low	ADJ
biomedich-939	168	8	protease	protease	NOUN
biomedich-939	168	9	inhibitory	inhibitory	ADJ
biomedich-939	168	10	properties	property	NOUN
biomedich-939	168	11	like	like	ADP
biomedich-939	168	12	2	2	NUM
biomedich-939	168	13	with	with	ADP
biomedich-939	168	14	moderate	moderate	ADJ
biomedich-939	168	15	kinase	kinase	PROPN
biomedich-939	168	16	inhibitory	inhibitory	ADJ
biomedich-939	168	17	properties	property	NOUN
biomedich-939	168	18	.	.	PUNCT
biomedich-939	169	1	as	as	SCONJ
biomedich-939	169	2	shown	show	VERB
biomedich-939	169	3	in	in	ADP
biomedich-939	169	4	figure	figure	NOUN
biomedich-939	169	5	10	10	NUM
biomedich-939	169	6	,	,	PUNCT
biomedich-939	169	7	all	all	DET
biomedich-939	169	8	the	the	DET
biomedich-939	169	9	compounds	compound	NOUN
biomedich-939	169	10	exhibit	exhibit	VERB
biomedich-939	169	11	good	good	ADJ
biomedich-939	169	12	to	to	ADP
biomedich-939	169	13	moderate	moderate	ADJ
biomedich-939	169	14	activity	activity	NOUN
biomedich-939	169	15	as	as	ADP
biomedich-939	169	16	enzyme	enzyme	NOUN
biomedich-939	169	17	inhibitors	inhibitor	NOUN
biomedich-939	169	18	(	(	PUNCT
biomedich-939	169	19	ei	ei	NOUN
biomedich-939	169	20	)	)	PUNCT
biomedich-939	169	21	,	,	PUNCT
biomedich-939	169	22	g	g	NOUN
biomedich-939	169	23	-	-	PUNCT
biomedich-939	169	24	protein	protein	NOUN
biomedich-939	169	25	-	-	PUNCT
biomedich-939	169	26	coupled	couple	VERB
biomedich-939	169	27	receptors	receptor	NOUN
biomedich-939	169	28	(	(	PUNCT
biomedich-939	169	29	gpcr	gpcr	ADJ
biomedich-939	169	30	)	)	PUNCT
biomedich-939	169	31	,	,	PUNCT
biomedich-939	169	32	ion	ion	NOUN
biomedich-939	169	33	channel	channel	NOUN
biomedich-939	169	34	modulators	modulator	NOUN
biomedich-939	169	35	(	(	PUNCT
biomedich-939	169	36	icm	icm	NOUN
biomedich-939	169	37	)	)	PUNCT
biomedich-939	169	38	,	,	PUNCT
biomedich-939	169	39	nuclear	nuclear	ADJ
biomedich-939	169	40	receptor	receptor	NOUN
biomedich-939	169	41	compounds	compound	NOUN
biomedich-939	169	42	(	(	PUNCT
biomedich-939	169	43	nrl	nrl	NOUN
biomedich-939	169	44	)	)	PUNCT
biomedich-939	169	45	and	and	CCONJ
biomedich-939	169	46	kinase	kinase	VERB
biomedich-939	169	47	inhibitors	inhibitor	NOUN
biomedich-939	169	48	(	(	PUNCT
biomedich-939	169	49	ki	ki	PROPN
biomedich-939	169	50	)	)	PUNCT
biomedich-939	169	51	.	.	PUNCT
biomedich-939	170	1	it	it	PRON
biomedich-939	170	2	is	be	AUX
biomedich-939	170	3	observed	observe	VERB
biomedich-939	170	4	that	that	SCONJ
biomedich-939	170	5	all	all	DET
biomedich-939	170	6	the	the	DET
biomedich-939	170	7	compounds	compound	NOUN
biomedich-939	170	8	only	only	ADV
biomedich-939	170	9	exhibit	exhibit	VERB
biomedich-939	170	10	moderate	moderate	ADJ
biomedich-939	170	11	activity	activity	NOUN
biomedich-939	170	12	as	as	ADP
biomedich-939	170	13	protease	protease	NOUN
biomedich-939	170	14	inhibitors	inhibitor	NOUN
biomedich-939	170	15	(	(	PUNCT
biomedich-939	170	16	pi	pi	NOUN
biomedich-939	170	17	)	)	PUNCT
biomedich-939	170	18	.	.	PUNCT
biomedich-939	171	1	figure	figure	NOUN
biomedich-939	171	2	10	10	NUM
biomedich-939	171	3	.	.	PUNCT
biomedich-939	172	1	profile	profile	NOUN
biomedich-939	172	2	depicting	depict	VERB
biomedich-939	172	3	bioactivity	bioactivity	NOUN
biomedich-939	172	4	score	score	NOUN
biomedich-939	172	5	of	of	ADP
biomedich-939	172	6	compounds	compound	NOUN
biomedich-939	172	7	1	1	NUM
biomedich-939	172	8	-	-	SYM
biomedich-939	172	9	8	8	NUM
biomedich-939	172	10	.	.	PUNCT
biomedich-939	173	1	admet	admet	PROPN
biomedich-939	173	2	/	/	SYM
biomedich-939	173	3	sar	sar	PROPN
biomedich-939	173	4	investigation	investigation	NOUN
biomedich-939	173	5	of	of	ADP
biomedich-939	173	6	2	2	NUM
biomedich-939	173	7	-	-	PUNCT
biomedich-939	173	8	phenoxyquinoline	phenoxyquinoline	NOUN
biomedich-939	173	9	derivatives	derivative	NOUN
biomedich-939	173	10	absorption	absorption	NOUN
biomedich-939	173	11	,	,	PUNCT
biomedich-939	173	12	distribution	distribution	NOUN
biomedich-939	173	13	,	,	PUNCT
biomedich-939	173	14	metabolism	metabolism	NOUN
biomedich-939	173	15	,	,	PUNCT
biomedich-939	173	16	excretion	excretion	NOUN
biomedich-939	173	17	(	(	PUNCT
biomedich-939	173	18	admet	admet	PROPN
biomedich-939	173	19	)	)	PUNCT
biomedich-939	173	20	was	be	AUX
biomedich-939	173	21	analysed	analyse	VERB
biomedich-939	173	22	based	base	VERB
biomedich-939	173	23	on	on	ADP
biomedich-939	173	24	data	datum	NOUN
biomedich-939	173	25	generated	generate	VERB
biomedich-939	173	26	from	from	ADP
biomedich-939	173	27	adme	adme	NOUN
biomedich-939	173	28	sar	sar	PROPN
biomedich-939	173	29	2	2	NUM
biomedich-939	173	30	web	web	NOUN
biomedich-939	173	31	server	server	NOUN
biomedich-939	173	32	.	.	PUNCT
biomedich-939	174	1	the	the	DET
biomedich-939	174	2	values	value	NOUN
biomedich-939	174	3	obtained	obtain	VERB
biomedich-939	174	4	are	be	AUX
biomedich-939	174	5	from	from	ADP
biomedich-939	174	6	latest	late	ADJ
biomedich-939	174	7	drug	drug	NOUN
biomedich-939	174	8	-	-	PUNCT
biomedich-939	174	9	likeness	likeness	NOUN
biomedich-939	174	10	capability	capability	NOUN
biomedich-939	174	11	tools	tool	NOUN
biomedich-939	174	12	in	in	ADP
biomedich-939	174	13	drug	drug	NOUN
biomedich-939	174	14	discovery	discovery	NOUN
biomedich-939	174	15	.	.	PUNCT
biomedich-939	175	1	most	most	ADJ
biomedich-939	175	2	of	of	ADP
biomedich-939	175	3	the	the	DET
biomedich-939	175	4	parameters	parameter	NOUN
biomedich-939	175	5	correlate	correlate	VERB
biomedich-939	175	6	positively	positively	ADV
biomedich-939	175	7	and	and	CCONJ
biomedich-939	175	8	are	be	AUX
biomedich-939	175	9	presented	present	VERB
biomedich-939	175	10	in	in	ADP
biomedich-939	175	11	table	table	NOUN
biomedich-939	175	12	5	5	NUM
biomedich-939	175	13	thus	thus	ADV
biomedich-939	175	14	confirming	confirm	VERB
biomedich-939	175	15	their	their	PRON
biomedich-939	175	16	profile	profile	NOUN
biomedich-939	175	17	depicting	depict	VERB
biomedich-939	175	18	bioactivity	bioactivity	NOUN
biomedich-939	175	19	score	score	NOUN
biomedich-939	175	20	in	in	ADP
biomedich-939	175	21	figure	figure	NOUN
biomedich-939	175	22	10	10	NUM
biomedich-939	175	23	.	.	PUNCT
biomedich-939	176	1	it	it	PRON
biomedich-939	176	2	is	be	AUX
biomedich-939	176	3	noteworthy	noteworthy	ADJ
biomedich-939	176	4	that	that	SCONJ
biomedich-939	176	5	cytochromes	cytochrome	VERB
biomedich-939	176	6	cyp2c19	cyp2c19	PROPN
biomedich-939	176	7	,	,	PUNCT
biomedich-939	176	8	cyp2c29	cyp2c29	PROPN
biomedich-939	176	9	,	,	PUNCT
biomedich-939	176	10	cyp2d6	cyp2d6	NOUN
biomedich-939	176	11	,	,	PUNCT
biomedich-939	176	12	and	and	CCONJ
biomedich-939	176	13	cyp3a4	cyp3a4	PROPN
biomedich-939	176	14	which	which	PRON
biomedich-939	176	15	are	be	AUX
biomedich-939	176	16	significant	significant	ADJ
biomedich-939	176	17	enzymes	enzyme	NOUN
biomedich-939	176	18	responsible	responsible	ADJ
biomedich-939	176	19	for	for	ADP
biomedich-939	176	20	metabolizing	metabolize	VERB
biomedich-939	176	21	commonly	commonly	ADV
biomedich-939	176	22	used	use	VERB
biomedich-939	176	23	drugs	drug	NOUN
biomedich-939	176	24	,	,	PUNCT
biomedich-939	176	25	are	be	AUX
biomedich-939	176	26	not	not	PART
biomedich-939	176	27	inhibited	inhibit	VERB
biomedich-939	176	28	,	,	PUNCT
biomedich-939	176	29	hence	hence	ADV
biomedich-939	176	30	no	no	DET
biomedich-939	176	31	effect	effect	NOUN
biomedich-939	176	32	on	on	ADP
biomedich-939	176	33	plasma	plasma	NOUN
biomedich-939	176	34	levels	level	NOUN
biomedich-939	176	35	in	in	ADP
biomedich-939	176	36	vivo	vivo	NOUN
biomedich-939	176	37	which	which	PRON
biomedich-939	176	38	can	can	AUX
biomedich-939	176	39	potentially	potentially	ADV
biomedich-939	176	40	lead	lead	VERB
biomedich-939	176	41	to	to	ADP
biomedich-939	176	42	adverse	adverse	ADJ
biomedich-939	176	43	drug	drug	NOUN
biomedich-939	176	44	reactions	reaction	NOUN
biomedich-939	176	45	or	or	CCONJ
biomedich-939	176	46	toxicity	toxicity	NOUN
biomedich-939	176	47	while	while	SCONJ
biomedich-939	176	48	cytochromes	cytochrome	NOUN
biomedich-939	176	49	cyp2c9	cyp2c9	NOUN
biomedich-939	176	50	and	and	CCONJ
biomedich-939	176	51	cyp2d6	cyp2d6	NOUN
biomedich-939	176	52	act	act	NOUN
biomedich-939	176	53	as	as	ADP
biomedich-939	176	54	substrates	substrate	NOUN
biomedich-939	176	55	which	which	PRON
biomedich-939	176	56	metabolise	metabolise	VERB
biomedich-939	176	57	pharmacologically	pharmacologically	ADV
biomedich-939	176	58	inactive	inactive	ADJ
biomedich-939	176	59	drugs	drug	NOUN
biomedich-939	176	60	to	to	ADP
biomedich-939	176	61	active	active	ADJ
biomedich-939	176	62	form	form	NOUN
biomedich-939	176	63	for	for	ADP
biomedich-939	176	64	easy	easy	ADJ
biomedich-939	176	65	clearance	clearance	NOUN
biomedich-939	176	66	from	from	ADP
biomedich-939	176	67	the	the	DET
biomedich-939	176	68	body	body	NOUN
biomedich-939	176	69	the	the	DET
biomedich-939	176	70	ames	ames	PROPN
biomedich-939	176	71	test	test	NOUN
biomedich-939	176	72	is	be	AUX
biomedich-939	176	73	a	a	DET
biomedich-939	176	74	biological	biological	ADJ
biomedich-939	176	75	assay	assay	NOUN
biomedich-939	176	76	to	to	PART
biomedich-939	176	77	assess	assess	VERB
biomedich-939	176	78	the	the	DET
biomedich-939	176	79	mutagenic	mutagenic	ADJ
biomedich-939	176	80	potential	potential	NOUN
biomedich-939	176	81	of	of	ADP
biomedich-939	176	82	chemical	chemical	ADJ
biomedich-939	176	83	compounds	compound	NOUN
biomedich-939	176	84	utilizing	utilize	VERB
biomedich-939	176	85	bacteria	bacteria	NOUN
biomedich-939	176	86	to	to	PART
biomedich-939	176	87	test	test	VERB
biomedich-939	176	88	whether	whether	SCONJ
biomedich-939	176	89	a	a	DET
biomedich-939	176	90	given	give	VERB
biomedich-939	176	91	chemical	chemical	NOUN
biomedich-939	176	92	can	can	AUX
biomedich-939	176	93	cause	cause	VERB
biomedich-939	176	94	mutations	mutation	NOUN
biomedich-939	176	95	in	in	ADP
biomedich-939	176	96	the	the	DET
biomedich-939	176	97	dna	dna	NOUN
biomedich-939	176	98	of	of	ADP
biomedich-939	176	99	the	the	DET
biomedich-939	176	100	test	test	NOUN
biomedich-939	176	101	organism	organism	NOUN
biomedich-939	176	102	.	.	PUNCT
biomedich-939	177	1	a	a	DET
biomedich-939	177	2	negative	negative	ADJ
biomedich-939	177	3	test	test	NOUN
biomedich-939	177	4	indicates	indicate	VERB
biomedich-939	177	5	that	that	SCONJ
biomedich-939	177	6	the	the	DET
biomedich-939	177	7	chemical	chemical	NOUN
biomedich-939	177	8	is	be	AUX
biomedich-939	177	9	non	non	ADJ
biomedich-939	177	10	-	-	ADJ
biomedich-939	177	11	mutagenic	mutagenic	ADJ
biomedich-939	177	12	and	and	CCONJ
biomedich-939	177	13	therefore	therefore	ADV
biomedich-939	177	14	is	be	AUX
biomedich-939	177	15	not	not	PART
biomedich-939	177	16	a	a	DET
biomedich-939	177	17	carcinogen	carcinogen	NOUN
biomedich-939	177	18	,	,	PUNCT
biomedich-939	177	19	because	because	SCONJ
biomedich-939	177	20	cancer	cancer	NOUN
biomedich-939	177	21	is	be	AUX
biomedich-939	177	22	often	often	ADV
biomedich-939	177	23	linked	link	VERB
biomedich-939	177	24	to	to	ADP
biomedich-939	177	25	mutation	mutation	NOUN
biomedich-939	177	26	(	(	PUNCT
biomedich-939	177	27	czeczot	czeczot	NOUN
biomedich-939	177	28	et	et	PROPN
biomedich-939	177	29	al	al	PROPN
biomedich-939	177	30	.	.	PROPN
biomedich-939	177	31	,	,	PUNCT
biomedich-939	177	32	1990	1990	NUM
biomedich-939	177	33	)	)	PUNCT
biomedich-939	177	34	.	.	PUNCT
biomedich-939	178	1	suffice	suffice	VERB
biomedich-939	178	2	to	to	PART
biomedich-939	178	3	say	say	VERB
biomedich-939	178	4	that	that	SCONJ
biomedich-939	178	5	compounds	compound	VERB
biomedich-939	178	6	7	7	NUM
biomedich-939	178	7	and	and	CCONJ
biomedich-939	178	8	8	8	NUM
biomedich-939	178	9	gave	give	VERB
biomedich-939	178	10	negative	negative	ADJ
biomedich-939	178	11	ames	ame	NOUN
biomedich-939	178	12	test	test	NOUN
biomedich-939	178	13	results	result	NOUN
biomedich-939	178	14	probably	probably	ADV
biomedich-939	178	15	due	due	ADJ
biomedich-939	178	16	to	to	ADP
biomedich-939	178	17	the	the	DET
biomedich-939	178	18	presence	presence	NOUN
biomedich-939	178	19	of	of	ADP
biomedich-939	178	20	the	the	DET
biomedich-939	178	21	fluorine	fluorine	NOUN
biomedich-939	178	22	and	and	CCONJ
biomedich-939	178	23	methoxy	methoxy	ADJ
biomedich-939	178	24	oxygen	oxygen	NOUN
biomedich-939	178	25	atoms	atom	NOUN
biomedich-939	178	26	at	at	ADP
biomedich-939	178	27	position	position	NOUN
biomedich-939	178	28	6	6	NUM
biomedich-939	178	29	of	of	ADP
biomedich-939	178	30	the	the	DET
biomedich-939	178	31	quinoline	quinoline	NOUN
biomedich-939	178	32	ring	ring	NOUN
biomedich-939	178	33	which	which	PRON
biomedich-939	178	34	withdraws	withdraw	VERB
biomedich-939	178	35	electrons	electron	NOUN
biomedich-939	178	36	from	from	ADP
biomedich-939	178	37	the	the	DET
biomedich-939	178	38	ring	ring	NOUN
biomedich-939	178	39	via	via	ADP
biomedich-939	178	40	inductive	inductive	ADJ
biomedich-939	178	41	effects	effect	NOUN
biomedich-939	178	42	.	.	PUNCT
biomedich-939	179	1	although	although	SCONJ
biomedich-939	179	2	the	the	DET
biomedich-939	179	3	methoxy	methoxy	ADJ
biomedich-939	179	4	group	group	NOUN
biomedich-939	179	5	is	be	AUX
biomedich-939	179	6	electron	electron	NOUN
biomedich-939	179	7	-	-	PUNCT
biomedich-939	179	8	donating	donating	NOUN
biomedich-939	179	9	by	by	ADP
biomedich-939	179	10	resonant	resonant	ADJ
biomedich-939	179	11	effect	effect	NOUN
biomedich-939	179	12	,	,	PUNCT
biomedich-939	179	13	that	that	PRON
biomedich-939	179	14	does	do	AUX
biomedich-939	179	15	not	not	PART
biomedich-939	179	16	apply	apply	VERB
biomedich-939	179	17	here	here	ADV
biomedich-939	179	18	.	.	PUNCT
biomedich-939	180	1	compounds	compound	VERB
biomedich-939	180	2	1	1	NUM
biomedich-939	180	3	with	with	ADP
biomedich-939	180	4	fewest	few	ADJ
biomedich-939	180	5	substituents	substituent	NOUN
biomedich-939	180	6	shows	show	VERB
biomedich-939	180	7	negative	negative	ADJ
biomedich-939	180	8	androgen	androgen	NOUN
biomedich-939	180	9	receptor	receptor	NOUN
biomedich-939	180	10	binding	bind	VERB
biomedich-939	180	11	,	,	PUNCT
biomedich-939	180	12	situation	situation	NOUN
biomedich-939	180	13	where	where	SCONJ
biomedich-939	180	14	a	a	DET
biomedich-939	180	15	type	type	NOUN
biomedich-939	180	16	of	of	ADP
biomedich-939	180	17	nuclear	nuclear	ADJ
biomedich-939	180	18	receptor	receptor	NOUN
biomedich-939	180	19	activated	activate	VERB
biomedich-939	180	20	by	by	ADP
biomedich-939	180	21	binding	bind	VERB
biomedich-939	180	22	to	to	ADP
biomedich-939	180	23	any	any	PRON
biomedich-939	180	24	of	of	ADP
biomedich-939	180	25	the	the	DET
biomedich-939	180	26	androgenic	androgenic	ADJ
biomedich-939	180	27	hormones	hormone	NOUN
biomedich-939	180	28	,	,	PUNCT
biomedich-939	180	29	including	include	VERB
biomedich-939	180	30	testosterone	testosterone	NOUN
biomedich-939	180	31	and	and	CCONJ
biomedich-939	180	32	dihydrotestosterone	dihydrotestosterone	NOUN
biomedich-939	180	33	in	in	ADP
biomedich-939	180	34	the	the	DET
biomedich-939	180	35	cytoplasm	cytoplasm	NOUN
biomedich-939	180	36	and	and	CCONJ
biomedich-939	180	37	is	be	AUX
biomedich-939	180	38	translocated	translocate	VERB
biomedich-939	180	39	into	into	ADP
biomedich-939	180	40	the	the	DET
biomedich-939	180	41	nucleus	nucleus	NOUN
biomedich-939	180	42	-0,4	-0,4	PROPN
biomedich-939	180	43	-0,3	-0,3	PUNCT
biomedich-939	181	1	-0,2	-0,2	INTJ
biomedich-939	182	1	-0,1	-0,1	NOUN
biomedich-939	182	2	0	0	NUM
biomedich-939	182	3	0,1	0,1	NUM
biomedich-939	182	4	0,2	0,2	NUM
biomedich-939	182	5	0,3	0,3	NUM
biomedich-939	182	6	1	1	NUM
biomedich-939	182	7	2	2	NUM
biomedich-939	182	8	3	3	NUM
biomedich-939	182	9	4	4	NUM
biomedich-939	182	10	5	5	NUM
biomedich-939	182	11	6	6	NUM
biomedich-939	182	12	7	7	NUM
biomedich-939	182	13	8	8	NUM
biomedich-939	182	14	gpcr	gpcr	ADJ
biomedich-939	182	15	icm	icm	NOUN
biomedich-939	182	16	ki	ki	PROPN
biomedich-939	182	17	nrl	nrl	PROPN
biomedich-939	182	18	pi	pi	PROPN
biomedich-939	182	19	ei	ei	PROPN
biomedich-939	182	20	aina	aina	PROPN
biomedich-939	182	21	et	et	PROPN
biomedich-939	182	22	al	al	PROPN
biomedich-939	182	23	.	.	PROPN
biomedich-939	183	1	–	–	PUNCT
biomedich-939	183	2	dft	dft	PROPN
biomedich-939	183	3	study	study	NOUN
biomedich-939	183	4	and	and	CCONJ
biomedich-939	183	5	admet	admet	PROPN
biomedich-939	183	6	investigation	investigation	NOUN
biomedich-939	183	7	of	of	ADP
biomedich-939	183	8	bioactive	bioactive	ADJ
biomedich-939	183	9	2	2	NUM
biomedich-939	183	10	-	-	PUNCT
biomedich-939	183	11	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	183	12	853	853	NUM
biomedich-939	183	13	thereby	thereby	ADV
biomedich-939	183	14	increasing	increase	VERB
biomedich-939	183	15	interfacial	interfacial	ADJ
biomedich-939	183	16	stability	stability	NOUN
biomedich-939	183	17	when	when	SCONJ
biomedich-939	183	18	compared	compare	VERB
biomedich-939	183	19	with	with	ADP
biomedich-939	183	20	the	the	DET
biomedich-939	183	21	other	other	ADJ
biomedich-939	183	22	steroid	steroid	NOUN
biomedich-939	183	23	receptors	receptor	NOUN
biomedich-939	183	24	(	(	PUNCT
biomedich-939	183	25	shaffer	shaffer	NOUN
biomedich-939	183	26	et	et	PROPN
biomedich-939	183	27	al	al	PROPN
biomedich-939	183	28	.	.	PROPN
biomedich-939	183	29	,	,	PUNCT
biomedich-939	183	30	2004	2004	NUM
biomedich-939	183	31	)	)	PUNCT
biomedich-939	183	32	.	.	PUNCT
biomedich-939	184	1	caco-2	caco-2	NUM
biomedich-939	184	2	is	be	AUX
biomedich-939	184	3	an	an	DET
biomedich-939	184	4	immortalized	immortalize	VERB
biomedich-939	184	5	cells	cell	NOUN
biomedich-939	184	6	line	line	NOUN
biomedich-939	184	7	of	of	ADP
biomedich-939	184	8	human	human	ADJ
biomedich-939	184	9	colorectal	colorectal	ADJ
biomedich-939	184	10	adenocarcinoma	adenocarcinoma	NOUN
biomedich-939	184	11	cell	cell	NOUN
biomedich-939	184	12	primarily	primarily	ADV
biomedich-939	184	13	used	use	VERB
biomedich-939	184	14	as	as	ADP
biomedich-939	184	15	a	a	DET
biomedich-939	184	16	model	model	NOUN
biomedich-939	184	17	for	for	ADP
biomedich-939	184	18	the	the	DET
biomedich-939	184	19	measurement	measurement	NOUN
biomedich-939	184	20	of	of	ADP
biomedich-939	184	21	the	the	DET
biomedich-939	184	22	intestinal	intestinal	ADJ
biomedich-939	184	23	epithelial	epithelial	ADJ
biomedich-939	184	24	barrier	barrier	NOUN
biomedich-939	184	25	functions	function	NOUN
biomedich-939	184	26	(	(	PUNCT
biomedich-939	184	27	lea	lea	PROPN
biomedich-939	184	28	,	,	PUNCT
biomedich-939	184	29	2015	2015	NUM
biomedich-939	184	30	)	)	PUNCT
biomedich-939	184	31	.	.	PUNCT
biomedich-939	185	1	this	this	PRON
biomedich-939	185	2	returns	return	VERB
biomedich-939	185	3	negative	negative	ADJ
biomedich-939	185	4	values	value	NOUN
biomedich-939	185	5	for	for	ADP
biomedich-939	185	6	compounds	compound	NOUN
biomedich-939	185	7	1	1	NUM
biomedich-939	185	8	and	and	CCONJ
biomedich-939	185	9	6	6	NUM
biomedich-939	185	10	.	.	PUNCT
biomedich-939	186	1	this	this	PRON
biomedich-939	186	2	could	could	AUX
biomedich-939	186	3	be	be	AUX
biomedich-939	186	4	attributed	attribute	VERB
biomedich-939	186	5	to	to	ADP
biomedich-939	186	6	the	the	DET
biomedich-939	186	7	fact	fact	NOUN
biomedich-939	186	8	that	that	SCONJ
biomedich-939	186	9	,	,	PUNCT
biomedich-939	186	10	despite	despite	SCONJ
biomedich-939	186	11	being	be	AUX
biomedich-939	186	12	monoand	monoand	NOUN
biomedich-939	186	13	di	di	NOUN
biomedich-939	186	14	-	-	ADJ
biomedich-939	186	15	acetoxylated	acetoxylated	ADJ
biomedich-939	186	16	,	,	PUNCT
biomedich-939	186	17	they	they	PRON
biomedich-939	186	18	are	be	AUX
biomedich-939	186	19	devoid	devoid	ADJ
biomedich-939	186	20	of	of	ADP
biomedich-939	186	21	any	any	DET
biomedich-939	186	22	other	other	ADJ
biomedich-939	186	23	substituted	substitute	VERB
biomedich-939	186	24	elements	element	NOUN
biomedich-939	186	25	.	.	PUNCT
biomedich-939	187	1	the	the	DET
biomedich-939	187	2	only	only	ADJ
biomedich-939	187	3	benzoylated	benzoylate	VERB
biomedich-939	187	4	compound	compound	NOUN
biomedich-939	187	5	5	5	NUM
biomedich-939	187	6	surprisingly	surprisingly	ADV
biomedich-939	187	7	gave	give	VERB
biomedich-939	187	8	negative	negative	ADJ
biomedich-939	187	9	cyp14	cyp14	NOUN
biomedich-939	187	10	substrate	substrate	NOUN
biomedich-939	187	11	value	value	NOUN
biomedich-939	187	12	.	.	PUNCT
biomedich-939	188	1	this	this	DET
biomedich-939	188	2	cytochrome	cytochrome	NOUN
biomedich-939	188	3	is	be	AUX
biomedich-939	188	4	an	an	DET
biomedich-939	188	5	hmg	hmg	NOUN
biomedich-939	188	6	-	-	PUNCT
biomedich-939	188	7	coa	coa	NOUN
biomedich-939	188	8	reductase	reductase	NOUN
biomedich-939	188	9	,	,	PUNCT
biomedich-939	188	10	a	a	DET
biomedich-939	188	11	factor	factor	NOUN
biomedich-939	188	12	in	in	ADP
biomedich-939	188	13	the	the	DET
biomedich-939	188	14	treatment	treatment	NOUN
biomedich-939	188	15	of	of	ADP
biomedich-939	188	16	hiv	hiv	PROPN
biomedich-939	188	17	infection	infection	NOUN
biomedich-939	188	18	by	by	ADP
biomedich-939	188	19	lowering	lower	VERB
biomedich-939	188	20	ldl	ldl	NOUN
biomedich-939	188	21	cholesterol	cholesterol	NOUN
biomedich-939	188	22	and	and	CCONJ
biomedich-939	188	23	reducing	reduce	VERB
biomedich-939	188	24	the	the	DET
biomedich-939	188	25	risk	risk	NOUN
biomedich-939	188	26	of	of	ADP
biomedich-939	188	27	cardiovascular	cardiovascular	ADJ
biomedich-939	188	28	disease	disease	NOUN
biomedich-939	188	29	such	such	ADJ
biomedich-939	188	30	as	as	ADP
biomedich-939	188	31	myocardial	myocardial	ADJ
biomedich-939	188	32	infarction	infarction	NOUN
biomedich-939	188	33	and	and	CCONJ
biomedich-939	188	34	stroke	stroke	NOUN
biomedich-939	188	35	.	.	PUNCT
biomedich-939	189	1	cyp	cyp	ADJ
biomedich-939	189	2	substrates	substrate	NOUN
biomedich-939	189	3	are	be	AUX
biomedich-939	189	4	drugs	drug	NOUN
biomedich-939	189	5	usually	usually	ADV
biomedich-939	189	6	metabolized	metabolize	VERB
biomedich-939	189	7	by	by	ADP
biomedich-939	189	8	cytochrome	cytochrome	ADJ
biomedich-939	189	9	enzymes	enzyme	NOUN
biomedich-939	189	10	which	which	PRON
biomedich-939	189	11	require	require	VERB
biomedich-939	189	12	metabolism	metabolism	NOUN
biomedich-939	189	13	into	into	ADP
biomedich-939	189	14	an	an	DET
biomedich-939	189	15	inactive	inactive	ADJ
biomedich-939	189	16	form	form	NOUN
biomedich-939	189	17	for	for	ADP
biomedich-939	189	18	clearance	clearance	NOUN
biomedich-939	189	19	from	from	ADP
biomedich-939	189	20	the	the	DET
biomedich-939	189	21	body	body	NOUN
biomedich-939	189	22	(	(	PUNCT
biomedich-939	189	23	galetin	galetin	PROPN
biomedich-939	189	24	et	et	PROPN
biomedich-939	189	25	al	al	PROPN
biomedich-939	189	26	.	.	PROPN
biomedich-939	189	27	,	,	PUNCT
biomedich-939	189	28	2005	2005	NUM
biomedich-939	189	29	)	)	PUNCT
biomedich-939	189	30	.	.	PUNCT
biomedich-939	190	1	it	it	PRON
biomedich-939	190	2	is	be	AUX
biomedich-939	190	3	obvious	obvious	ADJ
biomedich-939	190	4	that	that	SCONJ
biomedich-939	190	5	the	the	DET
biomedich-939	190	6	an	an	DET
biomedich-939	190	7	extra	extra	ADJ
biomedich-939	190	8	aromatic	aromatic	ADJ
biomedich-939	190	9	ring	ring	NOUN
biomedich-939	190	10	of	of	ADP
biomedich-939	190	11	compound	compound	NOUN
biomedich-939	190	12	5	5	NUM
biomedich-939	190	13	contributed	contribute	VERB
biomedich-939	190	14	to	to	ADP
biomedich-939	190	15	this	this	DET
biomedich-939	190	16	effect	effect	NOUN
biomedich-939	190	17	.	.	PUNCT
biomedich-939	191	1	ppar	ppar	NOUN
biomedich-939	191	2	gamma	gamma	NOUN
biomedich-939	191	3	is	be	AUX
biomedich-939	191	4	a	a	DET
biomedich-939	191	5	gene	gene	NOUN
biomedich-939	191	6	that	that	PRON
biomedich-939	191	7	encodes	encode	VERB
biomedich-939	191	8	a	a	DET
biomedich-939	191	9	member	member	NOUN
biomedich-939	191	10	of	of	ADP
biomedich-939	191	11	the	the	DET
biomedich-939	191	12	peroxisome	peroxisome	PROPN
biomedich-939	191	13	proliferator	proliferator	NOUN
biomedich-939	191	14	-	-	PUNCT
biomedich-939	191	15	activated	activate	VERB
biomedich-939	191	16	receptor	receptor	NOUN
biomedich-939	191	17	(	(	PUNCT
biomedich-939	191	18	ppar	ppar	NOUN
biomedich-939	191	19	)	)	PUNCT
biomedich-939	191	20	subfamily	subfamily	ADV
biomedich-939	191	21	of	of	ADP
biomedich-939	191	22	nuclear	nuclear	ADJ
biomedich-939	191	23	receptors	receptor	NOUN
biomedich-939	191	24	which	which	PRON
biomedich-939	191	25	form	form	VERB
biomedich-939	191	26	heterodimers	heterodimer	NOUN
biomedich-939	191	27	with	with	ADP
biomedich-939	191	28	retinoid	retinoid	NOUN
biomedich-939	191	29	x	x	X
biomedich-939	191	30	receptors	receptor	NOUN
biomedich-939	191	31	(	(	PUNCT
biomedich-939	191	32	rxrs	rxrs	NOUN
biomedich-939	191	33	)	)	PUNCT
biomedich-939	191	34	to	to	PART
biomedich-939	191	35	regulate	regulate	VERB
biomedich-939	191	36	transcription	transcription	NOUN
biomedich-939	191	37	of	of	ADP
biomedich-939	191	38	various	various	ADJ
biomedich-939	191	39	genes	gene	NOUN
biomedich-939	191	40	.	.	PUNCT
biomedich-939	192	1	activation	activation	NOUN
biomedich-939	192	2	of	of	ADP
biomedich-939	192	3	this	this	DET
biomedich-939	192	4	adipocyte	adipocyte	ADJ
biomedich-939	192	5	predominant	predominant	ADJ
biomedich-939	192	6	transcription	transcription	NOUN
biomedich-939	192	7	factor	factor	NOUN
biomedich-939	192	8	regulates	regulate	VERB
biomedich-939	192	9	glucose	glucose	NOUN
biomedich-939	192	10	and	and	CCONJ
biomedich-939	192	11	lipid	lipid	NOUN
biomedich-939	192	12	homeostasis	homeostasis	NOUN
biomedich-939	192	13	playing	play	VERB
biomedich-939	192	14	significant	significant	ADJ
biomedich-939	192	15	role	role	NOUN
biomedich-939	192	16	in	in	ADP
biomedich-939	192	17	the	the	DET
biomedich-939	192	18	regulation	regulation	NOUN
biomedich-939	192	19	of	of	ADP
biomedich-939	192	20	gene	gene	NOUN
biomedich-939	192	21	expression	expression	NOUN
biomedich-939	192	22	of	of	ADP
biomedich-939	192	23	multiple	multiple	ADJ
biomedich-939	192	24	diseases	disease	NOUN
biomedich-939	192	25	including	include	VERB
biomedich-939	192	26	obesity	obesity	NOUN
biomedich-939	192	27	,	,	PUNCT
biomedich-939	192	28	diabetes	diabetes	NOUN
biomedich-939	192	29	and	and	CCONJ
biomedich-939	192	30	cancer	cancer	NOUN
biomedich-939	192	31	and	and	CCONJ
biomedich-939	192	32	highlights	highlight	NOUN
biomedich-939	192	33	the	the	DET
biomedich-939	192	34	gene	gene	NOUN
biomedich-939	192	35	isolation	isolation	NOUN
biomedich-939	192	36	transformation	transformation	NOUN
biomedich-939	192	37	role	role	NOUN
biomedich-939	192	38	(	(	PUNCT
biomedich-939	192	39	janani	janani	PROPN
biomedich-939	192	40	&	&	CCONJ
biomedich-939	192	41	kumari	kumari	PROPN
biomedich-939	192	42	,	,	PUNCT
biomedich-939	192	43	2015	2015	NUM
biomedich-939	192	44	)	)	PUNCT
biomedich-939	192	45	.	.	PUNCT
biomedich-939	193	1	compound	compound	NOUN
biomedich-939	193	2	2	2	NUM
biomedich-939	193	3	has	have	VERB
biomedich-939	193	4	extra	extra	ADJ
biomedich-939	193	5	methyl	methyl	NOUN
biomedich-939	193	6	groups	group	NOUN
biomedich-939	193	7	on	on	ADP
biomedich-939	193	8	position	position	NOUN
biomedich-939	193	9	6	6	NUM
biomedich-939	193	10	of	of	ADP
biomedich-939	193	11	the	the	DET
biomedich-939	193	12	2	2	NUM
biomedich-939	193	13	-	-	PUNCT
biomedich-939	193	14	phenoxy	phenoxy	NOUN
biomedich-939	193	15	ring	ring	NOUN
biomedich-939	193	16	and	and	CCONJ
biomedich-939	193	17	on	on	ADP
biomedich-939	193	18	the	the	DET
biomedich-939	193	19	ester	ester	NOUN
biomedich-939	193	20	group	group	NOUN
biomedich-939	193	21	of	of	ADP
biomedich-939	193	22	the	the	DET
biomedich-939	193	23	3methylacetate	3methylacetate	NUM
biomedich-939	193	24	of	of	ADP
biomedich-939	193	25	the	the	DET
biomedich-939	193	26	quinoline	quinoline	NOUN
biomedich-939	193	27	ring	ring	NOUN
biomedich-939	193	28	.	.	PUNCT
biomedich-939	194	1	these	these	DET
biomedich-939	194	2	special	special	ADJ
biomedich-939	194	3	positions	position	NOUN
biomedich-939	194	4	of	of	ADP
biomedich-939	194	5	the	the	DET
biomedich-939	194	6	methyl	methyl	NOUN
biomedich-939	194	7	group	group	NOUN
biomedich-939	194	8	could	could	AUX
biomedich-939	194	9	be	be	AUX
biomedich-939	194	10	reason	reason	NOUN
biomedich-939	194	11	for	for	ADP
biomedich-939	194	12	the	the	DET
biomedich-939	194	13	negative	negative	ADJ
biomedich-939	194	14	values	value	NOUN
biomedich-939	194	15	of	of	ADP
biomedich-939	194	16	the	the	DET
biomedich-939	194	17	compounds	compound	NOUN
biomedich-939	194	18	.	.	PUNCT
biomedich-939	195	1	the	the	DET
biomedich-939	195	2	highest	high	ADJ
biomedich-939	195	3	plasma	plasma	NOUN
biomedich-939	195	4	protein	protein	NOUN
biomedich-939	195	5	binding	bind	VERB
biomedich-939	195	6	value	value	NOUN
biomedich-939	195	7	was	be	AUX
biomedich-939	195	8	exhibited	exhibit	VERB
biomedich-939	195	9	by	by	ADP
biomedich-939	195	10	only	only	ADV
biomedich-939	195	11	benzoylated	benzoylate	VERB
biomedich-939	195	12	compound	compound	NOUN
biomedich-939	195	13	5	5	NUM
biomedich-939	195	14	.	.	PUNCT
biomedich-939	196	1	the	the	DET
biomedich-939	196	2	presence	presence	NOUN
biomedich-939	196	3	of	of	ADP
biomedich-939	196	4	extra	extra	ADJ
biomedich-939	196	5	resonance	resonance	NOUN
biomedich-939	196	6	stabilization	stabilization	NOUN
biomedich-939	196	7	could	could	AUX
biomedich-939	196	8	have	have	AUX
biomedich-939	196	9	contributed	contribute	VERB
biomedich-939	196	10	to	to	ADP
biomedich-939	196	11	this	this	DET
biomedich-939	196	12	higher	high	ADJ
biomedich-939	196	13	value	value	NOUN
biomedich-939	196	14	.	.	PUNCT
biomedich-939	197	1	plasma	plasma	NOUN
biomedich-939	197	2	protein	protein	NOUN
biomedich-939	197	3	binding	bind	VERB
biomedich-939	197	4	refers	refer	VERB
biomedich-939	197	5	to	to	ADP
biomedich-939	197	6	the	the	DET
biomedich-939	197	7	degree	degree	NOUN
biomedich-939	197	8	to	to	PART
biomedich-939	197	9	which	which	PRON
biomedich-939	197	10	medications	medication	NOUN
biomedich-939	197	11	attach	attach	VERB
biomedich-939	197	12	to	to	ADP
biomedich-939	197	13	proteins	protein	NOUN
biomedich-939	197	14	within	within	ADP
biomedich-939	197	15	the	the	DET
biomedich-939	197	16	blood	blood	NOUN
biomedich-939	197	17	measuring	measure	VERB
biomedich-939	197	18	drug	drug	NOUN
biomedich-939	197	19	's	's	PART
biomedich-939	197	20	efficiency	efficiency	NOUN
biomedich-939	197	21	as	as	SCONJ
biomedich-939	197	22	it	it	PRON
biomedich-939	197	23	helps	help	VERB
biomedich-939	197	24	determine	determine	VERB
biomedich-939	197	25	the	the	DET
biomedich-939	197	26	degree	degree	NOUN
biomedich-939	197	27	to	to	PART
biomedich-939	197	28	which	which	PRON
biomedich-939	197	29	it	it	PRON
biomedich-939	197	30	binds	bind	VERB
biomedich-939	197	31	.	.	PUNCT
biomedich-939	198	1	the	the	DET
biomedich-939	198	2	less	less	ADV
biomedich-939	198	3	bound	bind	VERB
biomedich-939	198	4	a	a	DET
biomedich-939	198	5	drug	drug	NOUN
biomedich-939	198	6	is	be	AUX
biomedich-939	198	7	,	,	PUNCT
biomedich-939	198	8	the	the	PRON
biomedich-939	198	9	more	more	ADV
biomedich-939	198	10	efficiently	efficiently	ADV
biomedich-939	198	11	it	it	PRON
biomedich-939	198	12	can	can	AUX
biomedich-939	198	13	traverse	traverse	VERB
biomedich-939	198	14	or	or	CCONJ
biomedich-939	198	15	diffuse	diffuse	VERB
biomedich-939	198	16	through	through	ADP
biomedich-939	198	17	cell	cell	NOUN
biomedich-939	198	18	membranes	membrane	NOUN
biomedich-939	198	19	.	.	PUNCT
biomedich-939	199	1	plasma	plasma	NOUN
biomedich-939	199	2	proteins	protein	NOUN
biomedich-939	199	3	,	,	PUNCT
biomedich-939	199	4	by	by	ADP
biomedich-939	199	5	virtue	virtue	NOUN
biomedich-939	199	6	of	of	ADP
biomedich-939	199	7	their	their	PRON
biomedich-939	199	8	high	high	ADJ
biomedich-939	199	9	concentration	concentration	NOUN
biomedich-939	199	10	,	,	PUNCT
biomedich-939	199	11	control	control	VERB
biomedich-939	199	12	the	the	DET
biomedich-939	199	13	free	free	ADJ
biomedich-939	199	14	drug	drug	NOUN
biomedich-939	199	15	concentration	concentration	NOUN
biomedich-939	199	16	in	in	ADP
biomedich-939	199	17	plasma	plasma	NOUN
biomedich-939	199	18	and	and	CCONJ
biomedich-939	199	19	in	in	ADP
biomedich-939	199	20	compartments	compartment	NOUN
biomedich-939	199	21	in	in	ADP
biomedich-939	199	22	equilibrium	equilibrium	NOUN
biomedich-939	199	23	with	with	ADP
biomedich-939	199	24	plasma	plasma	NOUN
biomedich-939	199	25	,	,	PUNCT
biomedich-939	199	26	effectively	effectively	ADV
biomedich-939	199	27	attenuating	attenuate	VERB
biomedich-939	199	28	drug	drug	NOUN
biomedich-939	199	29	potency	potency	NOUN
biomedich-939	199	30	in	in	ADP
biomedich-939	199	31	vivo	vivo	NOUN
biomedich-939	199	32	(	(	PUNCT
biomedich-939	199	33	trainor	trainor	NOUN
biomedich-939	199	34	,	,	PUNCT
biomedich-939	199	35	2007	2007	NUM
biomedich-939	199	36	)	)	PUNCT
biomedich-939	199	37	.	.	PUNCT
biomedich-939	200	1	compound	compound	NOUN
biomedich-939	200	2	5	5	NUM
biomedich-939	200	3	has	have	VERB
biomedich-939	200	4	the	the	DET
biomedich-939	200	5	highest	high	ADJ
biomedich-939	200	6	tetrahymena	tetrahymena	ADJ
biomedich-939	200	7	pyriformis	pyriformis	NOUN
biomedich-939	200	8	value	value	NOUN
biomedich-939	200	9	of	of	ADP
biomedich-939	200	10	1.92	1.92	NUM
biomedich-939	200	11	.	.	PUNCT
biomedich-939	201	1	tetrahymena	tetrahymena	NOUN
biomedich-939	201	2	species	specie	NOUN
biomedich-939	201	3	found	find	VERB
biomedich-939	201	4	in	in	ADP
biomedich-939	201	5	the	the	DET
biomedich-939	201	6	original	original	ADJ
biomedich-939	201	7	t.	t.	NOUN
biomedich-939	201	8	pyriformis	pyriformis	PROPN
biomedich-939	201	9	group	group	PROPN
biomedich-939	201	10	provide	provide	VERB
biomedich-939	201	11	an	an	DET
biomedich-939	201	12	invaluable	invaluable	ADJ
biomedich-939	201	13	resource	resource	NOUN
biomedich-939	201	14	for	for	ADP
biomedich-939	201	15	comparative	comparative	ADJ
biomedich-939	201	16	genomic	genomic	NOUN
biomedich-939	201	17	analyses	analysis	NOUN
biomedich-939	201	18	,	,	PUNCT
biomedich-939	201	19	as	as	SCONJ
biomedich-939	201	20	evolutionary	evolutionary	ADJ
biomedich-939	201	21	dna	dna	PROPN
biomedich-939	201	22	sequence	sequence	NOUN
biomedich-939	201	23	conservation	conservation	NOUN
biomedich-939	201	24	is	be	AUX
biomedich-939	201	25	a	a	DET
biomedich-939	201	26	valuable	valuable	ADJ
biomedich-939	201	27	predictor	predictor	NOUN
biomedich-939	201	28	of	of	ADP
biomedich-939	201	29	biological	biological	ADJ
biomedich-939	201	30	function	function	NOUN
biomedich-939	201	31	under	under	ADP
biomedich-939	201	32	natural	natural	ADJ
biomedich-939	201	33	selection	selection	NOUN
biomedich-939	201	34	(	(	PUNCT
biomedich-939	201	35	sauvant	sauvant	PROPN
biomedich-939	201	36	et	et	PROPN
biomedich-939	201	37	al	al	PROPN
biomedich-939	201	38	.	.	PROPN
biomedich-939	201	39	,	,	PUNCT
biomedich-939	201	40	1999	1999	NUM
biomedich-939	201	41	)	)	PUNCT
biomedich-939	201	42	.	.	PUNCT
biomedich-939	202	1	thyroid	thyroid	NOUN
biomedich-939	202	2	hormone	hormone	NOUN
biomedich-939	202	3	receptors	receptor	NOUN
biomedich-939	202	4	regulate	regulate	VERB
biomedich-939	202	5	gene	gene	NOUN
biomedich-939	202	6	expression	expression	NOUN
biomedich-939	202	7	by	by	ADP
biomedich-939	202	8	binding	bind	VERB
biomedich-939	202	9	to	to	ADP
biomedich-939	202	10	hormone	hormone	NOUN
biomedich-939	202	11	response	response	NOUN
biomedich-939	202	12	elements	element	NOUN
biomedich-939	202	13	(	(	PUNCT
biomedich-939	202	14	hres	hre	NOUN
biomedich-939	202	15	)	)	PUNCT
biomedich-939	202	16	in	in	ADP
biomedich-939	202	17	dna	dna	NOUN
biomedich-939	202	18	as	as	ADP
biomedich-939	202	19	monomers	monomer	NOUN
biomedich-939	202	20	,	,	PUNCT
biomedich-939	202	21	heterodimers	heterodimer	NOUN
biomedich-939	202	22	with	with	ADP
biomedich-939	202	23	other	other	ADJ
biomedich-939	202	24	nuclear	nuclear	ADJ
biomedich-939	202	25	receptors	receptor	NOUN
biomedich-939	202	26	,	,	PUNCT
biomedich-939	202	27	or	or	CCONJ
biomedich-939	202	28	homodimers	homodimer	NOUN
biomedich-939	202	29	.	.	PUNCT
biomedich-939	203	1	dimerizing	dimerize	VERB
biomedich-939	203	2	with	with	ADP
biomedich-939	203	3	different	different	ADJ
biomedich-939	203	4	nuclear	nuclear	ADJ
biomedich-939	203	5	receptors	receptor	NOUN
biomedich-939	203	6	leads	lead	VERB
biomedich-939	203	7	to	to	ADP
biomedich-939	203	8	the	the	DET
biomedich-939	203	9	regulation	regulation	NOUN
biomedich-939	203	10	of	of	ADP
biomedich-939	203	11	different	different	ADJ
biomedich-939	203	12	genes	gene	NOUN
biomedich-939	203	13	.	.	PUNCT
biomedich-939	204	1	they	they	PRON
biomedich-939	204	2	are	be	AUX
biomedich-939	204	3	essential	essential	ADJ
biomedich-939	204	4	for	for	ADP
biomedich-939	204	5	normal	normal	ADJ
biomedich-939	204	6	development	development	NOUN
biomedich-939	204	7	,	,	PUNCT
biomedich-939	204	8	differentiation	differentiation	NOUN
biomedich-939	204	9	and	and	CCONJ
biomedich-939	204	10	metabolic	metabolic	NOUN
biomedich-939	204	11	balance	balance	NOUN
biomedich-939	204	12	(	(	PUNCT
biomedich-939	204	13	zhang	zhang	PROPN
biomedich-939	204	14	&	&	CCONJ
biomedich-939	204	15	lazar	lazar	PROPN
biomedich-939	204	16	,	,	PUNCT
biomedich-939	204	17	2000	2000	NUM
biomedich-939	204	18	)	)	PUNCT
biomedich-939	204	19	.	.	PUNCT
biomedich-939	205	1	compound	compound	VERB
biomedich-939	205	2	5	5	NUM
biomedich-939	205	3	with	with	ADP
biomedich-939	205	4	the	the	DET
biomedich-939	205	5	most	most	ADJ
biomedich-939	205	6	pi	pi	NOUN
biomedich-939	205	7	-	-	PUNCT
biomedich-939	205	8	electrons	electron	NOUN
biomedich-939	205	9	possessed	possess	VERB
biomedich-939	205	10	in	in	ADP
biomedich-939	205	11	its	its	PRON
biomedich-939	205	12	four	four	NUM
biomedich-939	205	13	aromatic	aromatic	ADJ
biomedich-939	205	14	rings	ring	NOUN
biomedich-939	205	15	in	in	ADP
biomedich-939	205	16	addition	addition	NOUN
biomedich-939	205	17	to	to	ADP
biomedich-939	205	18	the	the	DET
biomedich-939	205	19	two	two	NUM
biomedich-939	205	20	carbonyl	carbonyl	NOUN
biomedich-939	205	21	functions	function	NOUN
biomedich-939	205	22	bind	bind	VERB
biomedich-939	205	23	with	with	ADP
biomedich-939	205	24	thyroid	thyroid	NOUN
biomedich-939	205	25	receptors	receptor	NOUN
biomedich-939	205	26	.	.	PUNCT
biomedich-939	206	1	drug	drug	NOUN
biomedich-939	206	2	oral	oral	ADJ
biomedich-939	206	3	bioavailability	bioavailability	NOUN
biomedich-939	206	4	is	be	AUX
biomedich-939	206	5	the	the	DET
biomedich-939	206	6	fractional	fractional	ADJ
biomedich-939	206	7	extent	extent	NOUN
biomedich-939	206	8	of	of	ADP
biomedich-939	206	9	the	the	DET
biomedich-939	206	10	drug	drug	NOUN
biomedich-939	206	11	dosage	dosage	NOUN
biomedich-939	206	12	that	that	PRON
biomedich-939	206	13	finally	finally	ADV
biomedich-939	206	14	reaches	reach	VERB
biomedich-939	206	15	the	the	DET
biomedich-939	206	16	therapeutic	therapeutic	ADJ
biomedich-939	206	17	site	site	NOUN
biomedich-939	206	18	of	of	ADP
biomedich-939	206	19	action	action	NOUN
biomedich-939	206	20	.	.	PUNCT
biomedich-939	207	1	the	the	DET
biomedich-939	207	2	most	most	ADV
biomedich-939	207	3	relevant	relevant	ADJ
biomedich-939	207	4	measure	measure	NOUN
biomedich-939	207	5	of	of	ADP
biomedich-939	207	6	lipophilicity	lipophilicity	NOUN
biomedich-939	207	7	with	with	ADP
biomedich-939	207	8	regard	regard	NOUN
biomedich-939	207	9	to	to	ADP
biomedich-939	207	10	oral	oral	ADJ
biomedich-939	207	11	absorption	absorption	NOUN
biomedich-939	207	12	by	by	ADP
biomedich-939	207	13	passive	passive	ADJ
biomedich-939	207	14	diffusion	diffusion	NOUN
biomedich-939	207	15	is	be	AUX
biomedich-939	207	16	probably	probably	ADV
biomedich-939	207	17	the	the	DET
biomedich-939	207	18	distribution	distribution	NOUN
biomedich-939	207	19	coefficient	coefficient	NOUN
biomedich-939	207	20	(	(	PUNCT
biomedich-939	207	21	log	log	NOUN
biomedich-939	207	22	d	d	NOUN
biomedich-939	207	23	)	)	PUNCT
biomedich-939	207	24	at	at	ADP
biomedich-939	207	25	ph	ph	PROPN
biomedich-939	207	26	6.5	6.5	NUM
biomedich-939	207	27	,	,	PUNCT
biomedich-939	207	28	which	which	PRON
biomedich-939	207	29	is	be	AUX
biomedich-939	207	30	the	the	DET
biomedich-939	207	31	ph	ph	NOUN
biomedich-939	207	32	of	of	ADP
biomedich-939	207	33	the	the	DET
biomedich-939	207	34	small	small	ADJ
biomedich-939	207	35	intestine	intestine	NOUN
biomedich-939	207	36	,	,	PUNCT
biomedich-939	207	37	where	where	SCONJ
biomedich-939	207	38	absorption	absorption	NOUN
biomedich-939	207	39	mostly	mostly	ADV
biomedich-939	207	40	takes	take	VERB
biomedich-939	207	41	place	place	NOUN
biomedich-939	207	42	(	(	PUNCT
biomedich-939	207	43	yoshida	yoshida	PROPN
biomedich-939	207	44	&	&	CCONJ
biomedich-939	207	45	topliss	topliss	PROPN
biomedich-939	207	46	,	,	PUNCT
biomedich-939	207	47	2000	2000	NUM
biomedich-939	207	48	)	)	PUNCT
biomedich-939	207	49	(	(	PUNCT
biomedich-939	207	50	yoshida	yoshida	PROPN
biomedich-939	207	51	&	&	CCONJ
biomedich-939	207	52	topliss	topliss	PROPN
biomedich-939	207	53	,	,	PUNCT
biomedich-939	207	54	2000	2000	NUM
biomedich-939	207	55	)	)	PUNCT
biomedich-939	207	56	.	.	PUNCT
biomedich-939	208	1	only	only	ADV
biomedich-939	208	2	compound	compound	NOUN
biomedich-939	208	3	5	5	NUM
biomedich-939	208	4	show	show	VERB
biomedich-939	208	5	positive	positive	ADJ
biomedich-939	208	6	results	result	NOUN
biomedich-939	208	7	for	for	ADP
biomedich-939	208	8	human	human	ADJ
biomedich-939	208	9	oral	oral	ADJ
biomedich-939	208	10	bioavailability	bioavailability	NOUN
biomedich-939	208	11	,	,	PUNCT
biomedich-939	208	12	hence	hence	ADV
biomedich-939	208	13	is	be	AUX
biomedich-939	208	14	predicted	predict	VERB
biomedich-939	208	15	to	to	PART
biomedich-939	208	16	reach	reach	VERB
biomedich-939	208	17	the	the	DET
biomedich-939	208	18	site	site	NOUN
biomedich-939	208	19	of	of	ADP
biomedich-939	208	20	action	action	NOUN
biomedich-939	208	21	before	before	ADP
biomedich-939	208	22	being	be	AUX
biomedich-939	208	23	eliminated	eliminate	VERB
biomedich-939	208	24	compared	compare	VERB
biomedich-939	208	25	to	to	ADP
biomedich-939	208	26	others	other	NOUN
biomedich-939	208	27	.	.	PUNCT
biomedich-939	209	1	mitochondrial	mitochondrial	ADJ
biomedich-939	209	2	toxicity	toxicity	NOUN
biomedich-939	209	3	is	be	AUX
biomedich-939	209	4	a	a	DET
biomedich-939	209	5	condition	condition	NOUN
biomedich-939	209	6	in	in	ADP
biomedich-939	209	7	which	which	PRON
biomedich-939	209	8	the	the	DET
biomedich-939	209	9	mitochondria	mitochondria	NOUN
biomedich-939	209	10	of	of	ADP
biomedich-939	209	11	a	a	DET
biomedich-939	209	12	body	body	NOUN
biomedich-939	209	13	's	's	PART
biomedich-939	209	14	cells	cell	NOUN
biomedich-939	209	15	become	become	VERB
biomedich-939	209	16	damaged	damage	VERB
biomedich-939	209	17	or	or	CCONJ
biomedich-939	209	18	decline	decline	VERB
biomedich-939	209	19	significantly	significantly	ADV
biomedich-939	209	20	in	in	ADP
biomedich-939	209	21	number	number	NOUN
biomedich-939	209	22	;	;	PUNCT
biomedich-939	209	23	it	it	PRON
biomedich-939	209	24	occurs	occur	VERB
biomedich-939	209	25	as	as	ADP
biomedich-939	209	26	a	a	DET
biomedich-939	209	27	side	side	ADJ
biomedich-939	209	28	effect	effect	NOUN
biomedich-939	209	29	of	of	ADP
biomedich-939	209	30	certain	certain	ADJ
biomedich-939	209	31	antiretroviral	antiretroviral	ADJ
biomedich-939	209	32	drugs	drug	NOUN
biomedich-939	209	33	used	use	VERB
biomedich-939	209	34	to	to	PART
biomedich-939	209	35	treat	treat	VERB
biomedich-939	209	36	human	human	ADJ
biomedich-939	209	37	immunodeficiency	immunodeficiency	NOUN
biomedich-939	209	38	virus	virus	NOUN
biomedich-939	209	39	(	(	PUNCT
biomedich-939	209	40	hiv	hiv	PROPN
biomedich-939	209	41	)	)	PUNCT
biomedich-939	209	42	.	.	PUNCT
biomedich-939	210	1	rapid	rapid	ADJ
biomedich-939	210	2	increase	increase	NOUN
biomedich-939	210	3	in	in	ADP
biomedich-939	210	4	reported	report	VERB
biomedich-939	210	5	toxic	toxic	ADJ
biomedich-939	210	6	effects	effect	NOUN
biomedich-939	210	7	of	of	ADP
biomedich-939	210	8	drugs	drug	NOUN
biomedich-939	210	9	and	and	CCONJ
biomedich-939	210	10	pollutants	pollutant	NOUN
biomedich-939	210	11	on	on	ADP
biomedich-939	210	12	mitochondria	mitochondria	NOUN
biomedich-939	210	13	have	have	AUX
biomedich-939	210	14	been	be	AUX
biomedich-939	210	15	documented	document	VERB
biomedich-939	210	16	detailing	detail	VERB
biomedich-939	210	17	many	many	ADJ
biomedich-939	210	18	genetic	genetic	ADJ
biomedich-939	210	19	differences	difference	NOUN
biomedich-939	210	20	leading	lead	VERB
biomedich-939	210	21	to	to	ADP
biomedich-939	210	22	mitochondrial	mitochondrial	ADJ
biomedich-939	210	23	diseases	disease	NOUN
biomedich-939	210	24	caused	cause	VERB
biomedich-939	210	25	by	by	ADP
biomedich-939	210	26	factors	factor	NOUN
biomedich-939	210	27	such	such	ADJ
biomedich-939	210	28	as	as	ADP
biomedich-939	210	29	as	as	ADP
biomedich-939	210	30	diet	diet	NOUN
biomedich-939	210	31	,	,	PUNCT
biomedich-939	210	32	exercise	exercise	NOUN
biomedich-939	210	33	,	,	PUNCT
biomedich-939	210	34	age	age	NOUN
biomedich-939	210	35	,	,	PUNCT
biomedich-939	210	36	and	and	CCONJ
biomedich-939	210	37	nonchemical	nonchemical	ADJ
biomedich-939	210	38	stressors	stressor	NOUN
biomedich-939	210	39	(	(	PUNCT
biomedich-939	210	40	meyer	meyer	PROPN
biomedich-939	210	41	et	et	PROPN
biomedich-939	210	42	al	al	PROPN
biomedich-939	210	43	.	.	PROPN
biomedich-939	210	44	,	,	PUNCT
biomedich-939	210	45	2018	2018	NUM
biomedich-939	210	46	)	)	PUNCT
biomedich-939	210	47	.	.	PUNCT
biomedich-939	211	1	only	only	ADV
biomedich-939	211	2	compound	compound	VERB
biomedich-939	211	3	7	7	NUM
biomedich-939	211	4	shows	show	VERB
biomedich-939	211	5	mitochondrial	mitochondrial	ADJ
biomedich-939	211	6	toxicity	toxicity	NOUN
biomedich-939	211	7	from	from	ADP
biomedich-939	211	8	this	this	DET
biomedich-939	211	9	investigation	investigation	NOUN
biomedich-939	211	10	which	which	PRON
biomedich-939	211	11	could	could	AUX
biomedich-939	211	12	be	be	AUX
biomedich-939	211	13	attributed	attribute	VERB
biomedich-939	211	14	to	to	ADP
biomedich-939	211	15	the	the	DET
biomedich-939	211	16	presence	presence	NOUN
biomedich-939	211	17	of	of	ADP
biomedich-939	211	18	the	the	DET
biomedich-939	211	19	methoxy	methoxy	ADJ
biomedich-939	211	20	group	group	NOUN
biomedich-939	211	21	at	at	ADP
biomedich-939	211	22	position	position	NOUN
biomedich-939	211	23	6	6	NUM
biomedich-939	211	24	.	.	PUNCT
biomedich-939	211	25	table	table	NOUN
biomedich-939	211	26	4	4	NUM
biomedich-939	211	27	:	:	PUNCT
biomedich-939	211	28	toxicity	toxicity	NOUN
biomedich-939	211	29	targets	target	NOUN
biomedich-939	211	30	of	of	ADP
biomedich-939	211	31	compounds	compound	NOUN
biomedich-939	211	32	1	1	NUM
biomedich-939	211	33	–	–	PUNCT
biomedich-939	211	34	8	8	NUM
biomedich-939	211	35	.	.	PUNCT
biomedich-939	211	36	targets	target	NOUN
biomedich-939	211	37	compounds	compound	VERB
biomedich-939	211	38	1	1	NUM
biomedich-939	211	39	2	2	NUM
biomedich-939	211	40	3	3	NUM
biomedich-939	211	41	4	4	NUM
biomedich-939	211	42	5	5	NUM
biomedich-939	211	43	6	6	NUM
biomedich-939	211	44	7	7	NUM
biomedich-939	211	45	8	8	NUM
biomedich-939	211	46	hepatotoxicity	hepatotoxicity	NOUN
biomedich-939	211	47	inactive	inactive	ADJ
biomedich-939	211	48	inactive	inactive	ADJ
biomedich-939	211	49	active	active	ADJ
biomedich-939	211	50	inactive	inactive	ADJ
biomedich-939	211	51	inactive	inactive	ADJ
biomedich-939	211	52	inactive	inactive	ADJ
biomedich-939	211	53	inactive	inactive	ADJ
biomedich-939	211	54	active	active	ADJ
biomedich-939	211	55	carcinogenicity	carcinogenicity	NOUN
biomedich-939	211	56	active	active	ADJ
biomedich-939	211	57	inactive	inactive	ADJ
biomedich-939	211	58	inactive	inactive	ADJ
biomedich-939	211	59	inactive	inactive	ADJ
biomedich-939	211	60	active	active	ADJ
biomedich-939	211	61	inactive	inactive	ADJ
biomedich-939	211	62	inactive	inactive	ADJ
biomedich-939	211	63	inactive	inactive	ADJ
biomedich-939	211	64	cytotoxicity	cytotoxicity	NOUN
biomedich-939	211	65	inactive	inactive	ADJ
biomedich-939	211	66	inactive	inactive	ADJ
biomedich-939	211	67	inactive	inactive	ADJ
biomedich-939	211	68	inactive	inactive	ADJ
biomedich-939	211	69	inactive	inactive	ADJ
biomedich-939	211	70	inactive	inactive	ADJ
biomedich-939	211	71	inactive	inactive	ADJ
biomedich-939	211	72	inactive	inactive	ADJ
biomedich-939	211	73	the	the	DET
biomedich-939	211	74	respiratory	respiratory	ADJ
biomedich-939	211	75	system	system	NOUN
biomedich-939	211	76	is	be	AUX
biomedich-939	211	77	a	a	DET
biomedich-939	211	78	target	target	NOUN
biomedich-939	211	79	of	of	ADP
biomedich-939	211	80	toxic	toxic	ADJ
biomedich-939	211	81	effects	effect	NOUN
biomedich-939	211	82	and	and	CCONJ
biomedich-939	211	83	a	a	DET
biomedich-939	211	84	major	major	ADJ
biomedich-939	211	85	route	route	NOUN
biomedich-939	211	86	of	of	ADP
biomedich-939	211	87	absorption	absorption	NOUN
biomedich-939	211	88	of	of	ADP
biomedich-939	211	89	inhaled	inhaled	ADJ
biomedich-939	211	90	gases	gas	NOUN
biomedich-939	211	91	and	and	CCONJ
biomedich-939	211	92	atmospheric	atmospheric	ADJ
biomedich-939	211	93	particles	particle	NOUN
biomedich-939	211	94	.	.	PUNCT
biomedich-939	212	1	lung	lung	NOUN
biomedich-939	212	2	toxicosis	toxicosis	NOUN
biomedich-939	212	3	depends	depend	VERB
biomedich-939	212	4	on	on	ADP
biomedich-939	212	5	the	the	DET
biomedich-939	212	6	dose	dose	NOUN
biomedich-939	212	7	of	of	ADP
biomedich-939	212	8	toxicant	toxicant	PROPN
biomedich-939	212	9	delivered	deliver	VERB
biomedich-939	212	10	to	to	ADP
biomedich-939	212	11	lung	lung	NOUN
biomedich-939	212	12	tissues	tissue	NOUN
biomedich-939	212	13	and	and	CCONJ
biomedich-939	212	14	toxicants	toxicant	NOUN
biomedich-939	212	15	’	'	PUNCT
biomedich-939	212	16	acute	acute	ADJ
biomedich-939	212	17	and	and	CCONJ
biomedich-939	212	18	chronic	chronic	ADJ
biomedich-939	212	19	effects	effect	NOUN
biomedich-939	212	20	.	.	PUNCT
biomedich-939	213	1	effects	effect	NOUN
biomedich-939	213	2	can	can	AUX
biomedich-939	213	3	be	be	AUX
biomedich-939	213	4	described	describe	VERB
biomedich-939	213	5	in	in	ADP
biomedich-939	213	6	terms	term	NOUN
biomedich-939	213	7	of	of	ADP
biomedich-939	213	8	tissue	tissue	NOUN
biomedich-939	213	9	damage	damage	NOUN
biomedich-939	213	10	and	and	CCONJ
biomedich-939	213	11	lesions	lesion	NOUN
biomedich-939	213	12	and	and	CCONJ
biomedich-939	213	13	in	in	ADP
biomedich-939	213	14	terms	term	NOUN
biomedich-939	213	15	of	of	ADP
biomedich-939	213	16	deficits	deficit	NOUN
biomedich-939	213	17	in	in	ADP
biomedich-939	213	18	respiratory	respiratory	ADJ
biomedich-939	213	19	system	system	NOUN
biomedich-939	213	20	function	function	NOUN
biomedich-939	213	21	.	.	PUNCT
biomedich-939	214	1	cellular	cellular	ADJ
biomedich-939	214	2	responses	response	NOUN
biomedich-939	214	3	to	to	ADP
biomedich-939	214	4	toxicants	toxicant	NOUN
biomedich-939	214	5	lead	lead	VERB
biomedich-939	214	6	to	to	ADP
biomedich-939	214	7	acute	acute	ADJ
biomedich-939	214	8	effects	effect	NOUN
biomedich-939	214	9	such	such	ADJ
biomedich-939	214	10	as	as	ADP
biomedich-939	214	11	inflammation	inflammation	NOUN
biomedich-939	214	12	or	or	CCONJ
biomedich-939	214	13	chronic	chronic	ADJ
biomedich-939	214	14	effects	effect	NOUN
biomedich-939	214	15	including	include	VERB
biomedich-939	214	16	fibrosis	fibrosis	NOUN
biomedich-939	214	17	,	,	PUNCT
biomedich-939	214	18	emphysema	emphysema	ADJ
biomedich-939	214	19	,	,	PUNCT
biomedich-939	214	20	and	and	CCONJ
biomedich-939	214	21	cancer	cancer	NOUN
biomedich-939	214	22	(	(	PUNCT
biomedich-939	214	23	van	van	PROPN
biomedich-939	214	24	der	der	NOUN
biomedich-939	214	25	merwe	merwe	PROPN
biomedich-939	214	26	,	,	PUNCT
biomedich-939	214	27	2018	2018	NUM
biomedich-939	214	28	)	)	PUNCT
biomedich-939	214	29	.	.	PUNCT
biomedich-939	215	1	it	it	PRON
biomedich-939	215	2	is	be	AUX
biomedich-939	215	3	noteworthy	noteworthy	ADJ
biomedich-939	215	4	that	that	SCONJ
biomedich-939	215	5	all	all	DET
biomedich-939	215	6	854	854	NUM
biomedich-939	215	7	biology	biology	NOUN
biomedich-939	215	8	,	,	PUNCT
biomedich-939	215	9	medicine	medicine	NOUN
biomedich-939	215	10	,	,	PUNCT
biomedich-939	215	11	&	&	CCONJ
biomedich-939	215	12	natural	natural	ADJ
biomedich-939	215	13	product	product	NOUN
biomedich-939	215	14	chemistry	chemistry	NOUN
biomedich-939	215	15	14	14	NUM
biomedich-939	215	16	(	(	PUNCT
biomedich-939	215	17	2	2	NUM
biomedich-939	215	18	)	)	PUNCT
biomedich-939	215	19	,	,	PUNCT
biomedich-939	215	20	2025	2025	NUM
biomedich-939	215	21	:	:	PUNCT
biomedich-939	215	22	843	843	NUM
biomedich-939	215	23	-	-	SYM
biomedich-939	215	24	856	856	NUM
biomedich-939	215	25	the	the	DET
biomedich-939	215	26	compounds	compound	NOUN
biomedich-939	215	27	are	be	AUX
biomedich-939	215	28	inactive	inactive	ADJ
biomedich-939	215	29	cytotoxic	cytotoxic	NOUN
biomedich-939	215	30	as	as	SCONJ
biomedich-939	215	31	shown	show	VERB
biomedich-939	215	32	in	in	ADP
biomedich-939	215	33	table	table	NOUN
biomedich-939	215	34	4	4	NUM
biomedich-939	215	35	.	.	PUNCT
biomedich-939	215	36	while	while	SCONJ
biomedich-939	215	37	compounds	compound	NOUN
biomedich-939	215	38	3	3	NUM
biomedich-939	215	39	and	and	CCONJ
biomedich-939	215	40	8	8	NUM
biomedich-939	215	41	exhibit	exhibit	NOUN
biomedich-939	215	42	slight	slight	ADJ
biomedich-939	215	43	hepatoxicity	hepatoxicity	NOUN
biomedich-939	215	44	,	,	PUNCT
biomedich-939	215	45	compounds	compound	VERB
biomedich-939	215	46	1	1	NUM
biomedich-939	215	47	,	,	PUNCT
biomedich-939	215	48	2	2	NUM
biomedich-939	215	49	,	,	PUNCT
biomedich-939	215	50	4	4	NUM
biomedich-939	215	51	,	,	PUNCT
biomedich-939	215	52	5	5	NUM
biomedich-939	215	53	,	,	PUNCT
biomedich-939	215	54	6	6	NUM
biomedich-939	215	55	and	and	CCONJ
biomedich-939	215	56	7	7	NUM
biomedich-939	215	57	are	be	AUX
biomedich-939	215	58	completely	completely	ADV
biomedich-939	215	59	nonhepatoxic	nonhepatoxic	ADJ
biomedich-939	215	60	.	.	PUNCT
biomedich-939	216	1	compounds	compound	NOUN
biomedich-939	216	2	1	1	NUM
biomedich-939	216	3	and	and	CCONJ
biomedich-939	216	4	5	5	NUM
biomedich-939	216	5	also	also	ADV
biomedich-939	216	6	exhibit	exhibit	VERB
biomedich-939	216	7	minimum	minimum	ADJ
biomedich-939	216	8	carcinogenic	carcinogenic	ADJ
biomedich-939	216	9	toxicity	toxicity	NOUN
biomedich-939	216	10	while	while	SCONJ
biomedich-939	216	11	the	the	DET
biomedich-939	216	12	rest	rest	NOUN
biomedich-939	216	13	are	be	AUX
biomedich-939	216	14	non	non	ADJ
biomedich-939	216	15	-	-	ADJ
biomedich-939	216	16	carcinogens	carcinogens	ADJ
biomedich-939	216	17	.	.	PUNCT
biomedich-939	217	1	to	to	ADP
biomedich-939	217	2	this	this	DET
biomedich-939	217	3	end	end	NOUN
biomedich-939	217	4	,	,	PUNCT
biomedich-939	217	5	compounds	compound	VERB
biomedich-939	217	6	2	2	NUM
biomedich-939	217	7	,	,	PUNCT
biomedich-939	217	8	4	4	NUM
biomedich-939	217	9	,	,	PUNCT
biomedich-939	217	10	6	6	NUM
biomedich-939	217	11	,	,	PUNCT
biomedich-939	217	12	and	and	CCONJ
biomedich-939	217	13	7	7	NUM
biomedich-939	217	14	are	be	AUX
biomedich-939	217	15	potential	potential	ADJ
biomedich-939	217	16	drug	drug	NOUN
biomedich-939	217	17	candidates	candidate	NOUN
biomedich-939	217	18	as	as	ADP
biomedich-939	217	19	antitumor	antitumor	PROPN
biomedich-939	217	20	agents	agent	NOUN
biomedich-939	217	21	,	,	PUNCT
biomedich-939	217	22	amidst	amidst	ADP
biomedich-939	217	23	various	various	ADJ
biomedich-939	217	24	other	other	ADJ
biomedich-939	217	25	pharmacological	pharmacological	ADJ
biomedich-939	217	26	applications	application	NOUN
biomedich-939	217	27	.	.	PUNCT
biomedich-939	218	1	conclusion	conclusion	NOUN
biomedich-939	218	2	bioactive	bioactive	VERB
biomedich-939	218	3	quinoline	quinoline	NOUN
biomedich-939	218	4	compounds	compound	NOUN
biomedich-939	218	5	have	have	AUX
biomedich-939	218	6	shown	show	VERB
biomedich-939	218	7	consistent	consistent	ADJ
biomedich-939	218	8	applications	application	NOUN
biomedich-939	218	9	in	in	ADP
biomedich-939	218	10	drug	drug	NOUN
biomedich-939	218	11	design	design	NOUN
biomedich-939	218	12	.	.	PUNCT
biomedich-939	219	1	from	from	ADP
biomedich-939	219	2	the	the	DET
biomedich-939	219	3	dft	dft	PROPN
biomedich-939	219	4	study	study	NOUN
biomedich-939	219	5	,	,	PUNCT
biomedich-939	219	6	calculated	calculate	VERB
biomedich-939	219	7	reactivity	reactivity	NOUN
biomedich-939	219	8	descriptors	descriptor	NOUN
biomedich-939	219	9	,	,	PUNCT
biomedich-939	219	10	mep	mep	PROPN
biomedich-939	219	11	,	,	PUNCT
biomedich-939	219	12	mac	mac	PROPN
biomedich-939	219	13	and	and	CCONJ
biomedich-939	219	14	optical	optical	ADJ
biomedich-939	219	15	properties	property	NOUN
biomedich-939	219	16	support	support	VERB
biomedich-939	219	17	the	the	DET
biomedich-939	219	18	bioactivity	bioactivity	NOUN
biomedich-939	219	19	of	of	ADP
biomedich-939	219	20	compounds	compound	NOUN
biomedich-939	219	21	as	as	SCONJ
biomedich-939	219	22	revealed	reveal	VERB
biomedich-939	219	23	in	in	ADP
biomedich-939	219	24	their	their	PRON
biomedich-939	219	25	lower	low	ADJ
biomedich-939	219	26	energy	energy	NOUN
biomedich-939	219	27	values	value	NOUN
biomedich-939	219	28	in	in	ADP
biomedich-939	219	29	water	water	NOUN
biomedich-939	219	30	relative	relative	ADJ
biomedich-939	219	31	to	to	ADP
biomedich-939	219	32	ethanol	ethanol	NOUN
biomedich-939	219	33	and	and	CCONJ
biomedich-939	219	34	gas	gas	NOUN
biomedich-939	219	35	.	.	PUNCT
biomedich-939	220	1	admet	admet	PROPN
biomedich-939	220	2	investigation	investigation	NOUN
biomedich-939	220	3	revealed	reveal	VERB
biomedich-939	220	4	the	the	DET
biomedich-939	220	5	extent	extent	NOUN
biomedich-939	220	6	of	of	ADP
biomedich-939	220	7	compliance	compliance	NOUN
biomedich-939	220	8	of	of	ADP
biomedich-939	220	9	the	the	DET
biomedich-939	220	10	compounds	compound	NOUN
biomedich-939	220	11	as	as	ADP
biomedich-939	220	12	potential	potential	ADJ
biomedich-939	220	13	candidates	candidate	NOUN
biomedich-939	220	14	based	base	VERB
biomedich-939	220	15	on	on	ADP
biomedich-939	220	16	drug	drug	NOUN
biomedich-939	220	17	-	-	PUNCT
biomedich-939	220	18	likeness	likeness	NOUN
biomedich-939	220	19	parameters	parameter	NOUN
biomedich-939	220	20	,	,	PUNCT
biomedich-939	220	21	leadlikeness	leadlikeness	ADJ
biomedich-939	220	22	,	,	PUNCT
biomedich-939	220	23	cytochrome	cytochrome	NOUN
biomedich-939	220	24	inhibition	inhibition	NOUN
biomedich-939	220	25	,	,	PUNCT
biomedich-939	220	26	bioavailability	bioavailability	NOUN
biomedich-939	220	27	and	and	CCONJ
biomedich-939	220	28	other	other	ADJ
biomedich-939	220	29	physicochemical	physicochemical	ADJ
biomedich-939	220	30	properties	property	NOUN
biomedich-939	220	31	.	.	PUNCT
biomedich-939	221	1	the	the	DET
biomedich-939	221	2	desired	desire	VERB
biomedich-939	221	3	medium	medium	NOUN
biomedich-939	221	4	(	(	PUNCT
biomedich-939	221	5	water	water	NOUN
biomedich-939	221	6	)	)	PUNCT
biomedich-939	221	7	gives	give	VERB
biomedich-939	221	8	favourable	favourable	ADJ
biomedich-939	221	9	intermolecular	intermolecular	ADJ
biomedich-939	221	10	interactions	interaction	NOUN
biomedich-939	221	11	via	via	ADP
biomedich-939	221	12	hydrogen	hydrogen	NOUN
biomedich-939	221	13	bonding	bonding	NOUN
biomedich-939	221	14	as	as	SCONJ
biomedich-939	221	15	reflected	reflect	VERB
biomedich-939	221	16	in	in	ADP
biomedich-939	221	17	their	their	PRON
biomedich-939	221	18	lower	low	ADJ
biomedich-939	221	19	ionization	ionization	NOUN
biomedich-939	221	20	potential	potential	NOUN
biomedich-939	221	21	especially	especially	ADV
biomedich-939	221	22	for	for	ADP
biomedich-939	221	23	the	the	DET
biomedich-939	221	24	6	6	NUM
biomedich-939	221	25	-	-	PUNCT
biomedich-939	221	26	methoxy	methoxy	ADJ
biomedich-939	221	27	substituted	substitute	VERB
biomedich-939	221	28	functionality	functionality	NOUN
biomedich-939	221	29	with	with	ADP
biomedich-939	221	30	lowest	low	ADJ
biomedich-939	221	31	ionization	ionization	NOUN
biomedich-939	221	32	potential	potential	ADJ
biomedich-939	221	33	value	value	NOUN
biomedich-939	221	34	of	of	ADP
biomedich-939	221	35	5.991	5.991	NUM
biomedich-939	221	36	ev	ev	NOUN
biomedich-939	221	37	.	.	PUNCT
biomedich-939	222	1	generally	generally	ADV
biomedich-939	222	2	,	,	PUNCT
biomedich-939	222	3	uniform	uniform	ADJ
biomedich-939	222	4	distribution	distribution	NOUN
biomedich-939	222	5	of	of	ADP
biomedich-939	222	6	charge	charge	NOUN
biomedich-939	222	7	was	be	AUX
biomedich-939	222	8	found	find	VERB
biomedich-939	222	9	for	for	ADP
biomedich-939	222	10	all	all	DET
biomedich-939	222	11	compounds	compound	NOUN
biomedich-939	222	12	especially	especially	ADV
biomedich-939	222	13	the	the	DET
biomedich-939	222	14	6	6	NUM
biomedich-939	222	15	-	-	PUNCT
biomedich-939	222	16	fluoro	fluoro	NOUN
biomedich-939	222	17	,	,	PUNCT
biomedich-939	222	18	benzoylated	benzoylate	VERB
biomedich-939	222	19	and	and	CCONJ
biomedich-939	222	20	6	6	NUM
biomedich-939	222	21	-	-	PUNCT
biomedich-939	222	22	methoxy	methoxy	ADJ
biomedich-939	222	23	substituted	substitute	VERB
biomedich-939	222	24	groups	group	NOUN
biomedich-939	222	25	which	which	PRON
biomedich-939	222	26	had	have	VERB
biomedich-939	222	27	lower	low	ADJ
biomedich-939	222	28	energy	energy	NOUN
biomedich-939	222	29	gaps	gap	NOUN
biomedich-939	222	30	in	in	ADP
biomedich-939	222	31	aqeous	aqeous	ADJ
biomedich-939	222	32	medium	medium	NOUN
biomedich-939	222	33	and	and	CCONJ
biomedich-939	222	34	were	be	AUX
biomedich-939	222	35	the	the	DET
biomedich-939	222	36	most	most	ADV
biomedich-939	222	37	reactive	reactive	ADJ
biomedich-939	222	38	with	with	ADP
biomedich-939	222	39	respective	respective	ADJ
biomedich-939	222	40	negative	negative	ADJ
biomedich-939	222	41	values	value	NOUN
biomedich-939	222	42	of	of	ADP
biomedich-939	222	43	-2.518	-2.518	PROPN
biomedich-939	222	44	a.u	a.u	PROPN
biomedich-939	222	45	,	,	PUNCT
biomedich-939	222	46	−2.609	−2.609	PROPN
biomedich-939	222	47	a.u	a.u	PROPN
biomedich-939	222	48	.	.	PROPN
biomedich-939	222	49	and	and	CCONJ
biomedich-939	222	50	-2.021	-2.021	PROPN
biomedich-939	222	51	a.u	a.u	PROPN
biomedich-939	222	52	.	.	PROPN
biomedich-939	223	1	this	this	DET
biomedich-939	223	2	charge	charge	NOUN
biomedich-939	223	3	is	be	AUX
biomedich-939	223	4	significant	significant	ADJ
biomedich-939	223	5	for	for	ADP
biomedich-939	223	6	the	the	DET
biomedich-939	223	7	bioactivity	bioactivity	NOUN
biomedich-939	223	8	of	of	ADP
biomedich-939	223	9	the	the	DET
biomedich-939	223	10	molecules	molecule	NOUN
biomedich-939	223	11	for	for	ADP
biomedich-939	223	12	their	their	PRON
biomedich-939	223	13	role	role	NOUN
biomedich-939	223	14	as	as	ADP
biomedich-939	223	15	radical	radical	ADJ
biomedich-939	223	16	scavengers	scavenger	NOUN
biomedich-939	223	17	.	.	PUNCT
biomedich-939	224	1	from	from	ADP
biomedich-939	224	2	mep	mep	PROPN
biomedich-939	224	3	and	and	CCONJ
biomedich-939	224	4	mac	mac	PROPN
biomedich-939	224	5	studies	study	NOUN
biomedich-939	224	6	,	,	PUNCT
biomedich-939	224	7	regions	region	NOUN
biomedich-939	224	8	of	of	ADP
biomedich-939	224	9	negative	negative	ADJ
biomedich-939	224	10	potentials	potential	NOUN
biomedich-939	224	11	in	in	ADP
biomedich-939	224	12	the	the	DET
biomedich-939	224	13	2	2	NUM
biomedich-939	224	14	-	-	PUNCT
biomedich-939	224	15	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	224	16	with	with	ADP
biomedich-939	224	17	high	high	ADJ
biomedich-939	224	18	affinity	affinity	NOUN
biomedich-939	224	19	for	for	ADP
biomedich-939	224	20	the	the	DET
biomedich-939	224	21	positively	positively	ADV
biomedich-939	224	22	charged	charge	VERB
biomedich-939	224	23	side	side	NOUN
biomedich-939	224	24	groups	group	NOUN
biomedich-939	224	25	of	of	ADP
biomedich-939	224	26	amino	amino	ADJ
biomedich-939	224	27	acids	acid	NOUN
biomedich-939	224	28	provide	provide	VERB
biomedich-939	224	29	enablement	enablement	NOUN
biomedich-939	224	30	for	for	ADP
biomedich-939	224	31	good	good	ADJ
biomedich-939	224	32	binding	bind	VERB
biomedich-939	224	33	interaction	interaction	NOUN
biomedich-939	224	34	.	.	PUNCT
biomedich-939	225	1	additionally	additionally	ADV
biomedich-939	225	2	,	,	PUNCT
biomedich-939	225	3	pearson	pearson	PROPN
biomedich-939	225	4	correlation	correlation	NOUN
biomedich-939	225	5	co	co	NOUN
biomedich-939	225	6	-	-	ADJ
biomedich-939	225	7	efficient	efficient	ADJ
biomedich-939	225	8	(	(	PUNCT
biomedich-939	225	9	r	r	NOUN
biomedich-939	225	10	)	)	PUNCT
biomedich-939	225	11	of	of	ADP
biomedich-939	225	12	0.97	0.97	NUM
biomedich-939	225	13	and	and	CCONJ
biomedich-939	225	14	r2	r2	NOUN
biomedich-939	225	15	value	value	NOUN
biomedich-939	225	16	of	of	ADP
biomedich-939	225	17	0.94	0.94	NUM
biomedich-939	225	18	shows	show	VERB
biomedich-939	225	19	the	the	DET
biomedich-939	225	20	average	average	ADJ
biomedich-939	225	21	bioactivity	bioactivity	NOUN
biomedich-939	225	22	score	score	NOUN
biomedich-939	225	23	of	of	ADP
biomedich-939	225	24	all	all	DET
biomedich-939	225	25	the	the	DET
biomedich-939	225	26	compounds	compound	NOUN
biomedich-939	225	27	to	to	PART
biomedich-939	225	28	be	be	AUX
biomedich-939	225	29	more	more	ADJ
biomedich-939	225	30	than	than	ADP
biomedich-939	225	31	0	0	NUM
biomedich-939	225	32	,	,	PUNCT
biomedich-939	225	33	therefore	therefore	ADV
biomedich-939	225	34	are	be	AUX
biomedich-939	225	35	active	active	ADJ
biomedich-939	225	36	drug	drug	NOUN
biomedich-939	225	37	candidates	candidate	NOUN
biomedich-939	225	38	.	.	PUNCT
biomedich-939	226	1	the	the	DET
biomedich-939	226	2	results	result	NOUN
biomedich-939	226	3	presented	present	VERB
biomedich-939	226	4	here	here	ADV
biomedich-939	226	5	can	can	AUX
biomedich-939	226	6	be	be	AUX
biomedich-939	226	7	used	use	VERB
biomedich-939	226	8	to	to	PART
biomedich-939	226	9	further	far	ADV
biomedich-939	226	10	evaluate	evaluate	VERB
biomedich-939	226	11	these	these	DET
biomedich-939	226	12	bioactive	bioactive	ADJ
biomedich-939	226	13	compounds	compound	NOUN
biomedich-939	226	14	in	in	ADP
biomedich-939	226	15	molecular	molecular	ADJ
biomedich-939	226	16	docking	docking	NOUN
biomedich-939	226	17	studies	study	NOUN
biomedich-939	226	18	against	against	ADP
biomedich-939	226	19	infections	infection	NOUN
biomedich-939	226	20	and	and	CCONJ
biomedich-939	226	21	diseases	disease	NOUN
biomedich-939	226	22	.	.	PUNCT
biomedich-939	227	1	acknowledgement	acknowledgement	NOUN
biomedich-939	227	2	:	:	PUNCT
biomedich-939	228	1	we	we	PRON
biomedich-939	228	2	appreciate	appreciate	VERB
biomedich-939	228	3	prof	prof	NOUN
biomedich-939	228	4	.	.	PUNCT
biomedich-939	229	1	o.	o.	PROPN
biomedich-939	229	2	b.	b.	PROPN
biomedich-939	229	3	familoni	familoni	PROPN
biomedich-939	229	4	and	and	CCONJ
biomedich-939	229	5	prof	prof	PROPN
biomedich-939	229	6	.	.	PUNCT
biomedich-939	230	1	l.	l.	PROPN
biomedich-939	230	2	a.	a.	PROPN
biomedich-939	230	3	adams	adams	PROPN
biomedich-939	230	4	of	of	ADP
biomedich-939	230	5	the	the	DET
biomedich-939	230	6	chemistry	chemistry	NOUN
biomedich-939	230	7	department	department	NOUN
biomedich-939	230	8	of	of	ADP
biomedich-939	230	9	the	the	DET
biomedich-939	230	10	university	university	PROPN
biomedich-939	230	11	of	of	ADP
biomedich-939	230	12	lagos	lagos	PROPN
biomedich-939	230	13	’s	’s	PART
biomedich-939	230	14	financial	financial	ADJ
biomedich-939	230	15	support	support	NOUN
biomedich-939	230	16	.	.	PUNCT
biomedich-939	231	1	competing	compete	VERB
biomedich-939	231	2	interests	interest	NOUN
biomedich-939	231	3	:	:	PUNCT
biomedich-939	231	4	the	the	DET
biomedich-939	231	5	authors	author	NOUN
biomedich-939	231	6	declare	declare	VERB
biomedich-939	231	7	that	that	SCONJ
biomedich-939	231	8	there	there	PRON
biomedich-939	231	9	are	be	VERB
biomedich-939	231	10	no	no	DET
biomedich-939	231	11	competing	compete	VERB
biomedich-939	231	12	interests	interest	NOUN
biomedich-939	231	13	.	.	PUNCT
biomedich-939	232	1	references	reference	NOUN
biomedich-939	232	2	abdel	abdel	PROPN
biomedich-939	232	3	-	-	PUNCT
biomedich-939	232	4	wahab	wahab	PROPN
biomedich-939	232	5	,	,	PUNCT
biomedich-939	232	6	b.	b.	PROPN
biomedich-939	232	7	f.	f.	PROPN
biomedich-939	232	8	,	,	PUNCT
biomedich-939	232	9	&	&	CCONJ
biomedich-939	232	10	khidre	khidre	PROPN
biomedich-939	232	11	,	,	PUNCT
biomedich-939	232	12	r.	r.	PROPN
biomedich-939	232	13	e.	e.	PROPN
biomedich-939	232	14	(	(	PUNCT
biomedich-939	232	15	2013	2013	NUM
biomedich-939	232	16	)	)	PUNCT
biomedich-939	232	17	.	.	PUNCT
biomedich-939	233	1	2	2	NUM
biomedich-939	233	2	-	-	PUNCT
biomedich-939	233	3	chloroquinoline-3carbaldehyde	chloroquinoline-3carbaldehyde	NUM
biomedich-939	233	4	ii	ii	NOUN
biomedich-939	233	5	:	:	PUNCT
biomedich-939	233	6	synthesis	synthesis	NOUN
biomedich-939	233	7	,	,	PUNCT
biomedich-939	233	8	reactions	reaction	NOUN
biomedich-939	233	9	,	,	PUNCT
biomedich-939	233	10	and	and	CCONJ
biomedich-939	233	11	applications	application	NOUN
biomedich-939	233	12	.	.	PUNCT
biomedich-939	234	1	journal	journal	NOUN
biomedich-939	234	2	of	of	ADP
biomedich-939	234	3	chemistry	chemistry	NOUN
biomedich-939	234	4	,	,	PUNCT
biomedich-939	234	5	2013	2013	NUM
biomedich-939	234	6	,	,	PUNCT
biomedich-939	234	7	1	1	NUM
biomedich-939	234	8	-	-	SYM
biomedich-939	234	9	13	13	NUM
biomedich-939	234	10	.	.	PUNCT
biomedich-939	235	1	akintemi	akintemi	PROPN
biomedich-939	235	2	,	,	PUNCT
biomedich-939	235	3	e.	e.	PROPN
biomedich-939	235	4	o.	o.	PROPN
biomedich-939	235	5	,	,	PUNCT
biomedich-939	235	6	govender	govender	NOUN
biomedich-939	235	7	,	,	PUNCT
biomedich-939	235	8	k.	k.	PROPN
biomedich-939	235	9	k.	k.	PROPN
biomedich-939	235	10	,	,	PUNCT
biomedich-939	235	11	&	&	CCONJ
biomedich-939	235	12	singh	singh	PROPN
biomedich-939	235	13	,	,	PUNCT
biomedich-939	235	14	t.	t.	PROPN
biomedich-939	235	15	(	(	PUNCT
biomedich-939	235	16	2022	2022	NUM
biomedich-939	235	17	)	)	PUNCT
biomedich-939	235	18	.	.	PUNCT
biomedich-939	236	1	a	a	DET
biomedich-939	236	2	dft	dft	PROPN
biomedich-939	236	3	study	study	NOUN
biomedich-939	236	4	of	of	ADP
biomedich-939	236	5	the	the	DET
biomedich-939	236	6	chemical	chemical	NOUN
biomedich-939	236	7	reactivity	reactivity	NOUN
biomedich-939	236	8	properties	property	NOUN
biomedich-939	236	9	,	,	PUNCT
biomedich-939	236	10	spectroscopy	spectroscopy	NOUN
biomedich-939	236	11	and	and	CCONJ
biomedich-939	236	12	bioactivity	bioactivity	NOUN
biomedich-939	236	13	scores	score	NOUN
biomedich-939	236	14	of	of	ADP
biomedich-939	236	15	bioactive	bioactive	ADJ
biomedich-939	236	16	flavonols	flavonol	NOUN
biomedich-939	236	17	.	.	PUNCT
biomedich-939	237	1	computational	computational	ADJ
biomedich-939	237	2	and	and	CCONJ
biomedich-939	237	3	theoretical	theoretical	ADJ
biomedich-939	237	4	chemistry	chemistry	NOUN
biomedich-939	237	5	,	,	PUNCT
biomedich-939	237	6	1210	1210	NUM
biomedich-939	237	7	,	,	PUNCT
biomedich-939	237	8	113658	113658	NUM
biomedich-939	237	9	.	.	PUNCT
biomedich-939	238	1	a.	a.	PROPN
biomedich-939	238	2	kumar	kumar	PROPN
biomedich-939	238	3	,	,	PUNCT
biomedich-939	238	4	a.	a.	PROPN
biomedich-939	238	5	k.	k.	PROPN
biomedich-939	238	6	srivastava	srivastava	PROPN
biomedich-939	238	7	,	,	PUNCT
biomedich-939	238	8	r.	r.	PROPN
biomedich-939	238	9	kumar	kumar	PROPN
biomedich-939	238	10	,	,	PUNCT
biomedich-939	238	11	g.	g.	PROPN
biomedich-939	238	12	brahmachari	brahmachari	PROPN
biomedich-939	238	13	,	,	PUNCT
biomedich-939	238	14	n.	n.	NOUN
biomedich-939	238	15	misra	misra	PROPN
biomedich-939	238	16	,	,	PUNCT
biomedich-939	238	17	nonlinear	nonlinear	ADJ
biomedich-939	238	18	optical	optical	ADJ
biomedich-939	238	19	property	property	NOUN
biomedich-939	238	20	of	of	ADP
biomedich-939	238	21	6’-amino-5	6’-amino-5	PROPN
biomedich-939	238	22	-	-	PUNCT
biomedich-939	238	23	fluoro-2	fluoro-2	VERB
biomedich-939	238	24	-	-	PUNCT
biomedich-939	238	25	oxo-3’propyl-2’h	oxo-3’propyl-2’h	NOUN
biomedich-939	238	26	-	-	PUNCT
biomedich-939	238	27	spiro[indoline-3,4’-pyrano	spiro[indoline-3,4’-pyrano	PROPN
biomedich-939	238	28	[	[	X
biomedich-939	238	29	2,3	2,3	NUM
biomedich-939	238	30	-	-	ADJ
biomedich-939	238	31	c]pyrazole]-5’carbonitrilea	c]pyrazole]-5’carbonitrilea	ADJ
biomedich-939	238	32	theoretical	theoretical	ADJ
biomedich-939	238	33	approach	approach	NOUN
biomedich-939	238	34	,	,	PUNCT
biomedich-939	238	35	organic	organic	ADJ
biomedich-939	238	36	and	and	CCONJ
biomedich-939	238	37	medicinal	medicinal	ADJ
biomedich-939	238	38	chem	chem	NOUN
biomedich-939	238	39	,	,	PUNCT
biomedich-939	238	40	3(4	3(4	NUM
biomedich-939	238	41	)	)	PUNCT
biomedich-939	238	42	(	(	PUNCT
biomedich-939	238	43	2017	2017	NUM
biomedich-939	238	44	)	)	PUNCT
biomedich-939	238	45	,	,	PUNCT
biomedich-939	238	46	555617	555617	NUM
biomedich-939	238	47	.	.	PUNCT
biomedich-939	239	1	al	al	PROPN
biomedich-939	239	2	-	-	PUNCT
biomedich-939	239	3	hasanat	hasanat	PROPN
biomedich-939	239	4	,	,	PUNCT
biomedich-939	239	5	s.	s.	PROPN
biomedich-939	239	6	j.	j.	PROPN
biomedich-939	239	7	(	(	PUNCT
biomedich-939	239	8	2017	2017	NUM
biomedich-939	239	9	)	)	PUNCT
biomedich-939	239	10	.	.	PUNCT
biomedich-939	240	1	theoretical	theoretical	ADJ
biomedich-939	240	2	study	study	NOUN
biomedich-939	240	3	of	of	ADP
biomedich-939	240	4	2	2	NUM
biomedich-939	240	5	-	-	PUNCT
biomedich-939	240	6	amino-2oxazolin4	amino-2oxazolin4	NOUN
biomedich-939	240	7	-	-	PUNCT
biomedich-939	240	8	one	one	NUM
biomedich-939	240	9	and	and	CCONJ
biomedich-939	240	10	its	its	PRON
biomedich-939	240	11	derivatives	derivative	NOUN
biomedich-939	240	12	in	in	ADP
biomedich-939	240	13	gas	gas	NOUN
biomedich-939	240	14	phase	phase	NOUN
biomedich-939	240	15	and	and	CCONJ
biomedich-939	240	16	in	in	ADP
biomedich-939	240	17	solution	solution	NOUN
biomedich-939	240	18	(	(	PUNCT
biomedich-939	240	19	doctoral	doctoral	ADJ
biomedich-939	240	20	dissertation	dissertation	NOUN
biomedich-939	240	21	)	)	PUNCT
biomedich-939	240	22	.	.	PUNCT
biomedich-939	241	1	alodeani	alodeani	PROPN
biomedich-939	241	2	,	,	PUNCT
biomedich-939	241	3	e.	e.	PROPN
biomedich-939	241	4	a.	a.	PROPN
biomedich-939	241	5	,	,	PUNCT
biomedich-939	241	6	arshad	arshad	ADJ
biomedich-939	241	7	,	,	PUNCT
biomedich-939	241	8	m.	m.	NOUN
biomedich-939	241	9	,	,	PUNCT
biomedich-939	241	10	&	&	CCONJ
biomedich-939	241	11	izhari	izhari	PROPN
biomedich-939	241	12	,	,	PUNCT
biomedich-939	241	13	m.	m.	NOUN
biomedich-939	241	14	a.	a.	NOUN
biomedich-939	241	15	(	(	PUNCT
biomedich-939	241	16	2015	2015	NUM
biomedich-939	241	17	)	)	PUNCT
biomedich-939	241	18	.	.	PUNCT
biomedich-939	242	1	antiuropathogenic	antiuropathogenic	ADJ
biomedich-939	242	2	activity	activity	NOUN
biomedich-939	242	3	,	,	PUNCT
biomedich-939	242	4	drug	drug	NOUN
biomedich-939	242	5	likeness	likeness	NOUN
biomedich-939	242	6	,	,	PUNCT
biomedich-939	242	7	physicochemical	physicochemical	ADJ
biomedich-939	242	8	and	and	CCONJ
biomedich-939	242	9	molecular	molecular	ADJ
biomedich-939	242	10	docking	docking	NOUN
biomedich-939	242	11	assessment	assessment	NOUN
biomedich-939	242	12	of	of	ADP
biomedich-939	242	13	(	(	PUNCT
biomedich-939	242	14	e-)-n′	e-)-n′	VERB
biomedich-939	242	15	(	(	PUNCT
biomedich-939	242	16	substitutedbenzylidene)-2-(quinolin-8	substitutedbenzylidene)-2-(quinolin-8	ADV
biomedich-939	242	17	-	-	PUNCT
biomedich-939	242	18	yloxy	yloxy	ADJ
biomedich-939	242	19	)	)	PUNCT
biomedich-939	242	20	acetohydrazide	acetohydrazide	ADV
biomedich-939	242	21	.	.	PUNCT
biomedich-939	243	1	asian	asian	PROPN
biomedich-939	243	2	pacific	pacific	PROPN
biomedich-939	243	3	journal	journal	PROPN
biomedich-939	243	4	of	of	ADP
biomedich-939	243	5	tropical	tropical	ADJ
biomedich-939	243	6	biomedicine	biomedicine	NOUN
biomedich-939	243	7	,	,	PUNCT
biomedich-939	243	8	5	5	NUM
biomedich-939	243	9	,	,	PUNCT
biomedich-939	243	10	676–683	676–683	NUM
biomedich-939	243	11	.	.	PUNCT
biomedich-939	244	1	bakthadoss	bakthadoss	NOUN
biomedich-939	244	2	,	,	PUNCT
biomedich-939	244	3	m.	m.	NOUN
biomedich-939	244	4	,	,	PUNCT
biomedich-939	244	5	aina	aina	PROPN
biomedich-939	244	6	,	,	PUNCT
biomedich-939	244	7	o.	o.	PROPN
biomedich-939	244	8	s.	s.	PROPN
biomedich-939	244	9	,	,	PUNCT
biomedich-939	244	10	reddy	reddy	PROPN
biomedich-939	244	11	,	,	PUNCT
biomedich-939	244	12	t.	t.	PROPN
biomedich-939	244	13	t.	t.	PROPN
biomedich-939	244	14	,	,	PUNCT
biomedich-939	244	15	izunobi	izunobi	PROPN
biomedich-939	244	16	,	,	PUNCT
biomedich-939	244	17	j.	j.	PROPN
biomedich-939	244	18	u.	u.	PROPN
biomedich-939	244	19	,	,	PUNCT
biomedich-939	244	20	&	&	CCONJ
biomedich-939	244	21	familoni	familoni	PROPN
biomedich-939	244	22	,	,	PUNCT
biomedich-939	244	23	o.	o.	PROPN
biomedich-939	244	24	b.	b.	PROPN
biomedich-939	244	25	(	(	PUNCT
biomedich-939	244	26	2024	2024	NUM
biomedich-939	244	27	)	)	PUNCT
biomedich-939	244	28	.	.	PUNCT
biomedich-939	245	1	monoand	monoand	NOUN
biomedich-939	245	2	diortho	diortho	NOUN
biomedich-939	245	3	-	-	PUNCT
biomedich-939	245	4	c	c	PROPN
biomedich-939	245	5	–	–	PUNCT
biomedich-939	245	6	h	h	NOUN
biomedich-939	245	7	acetoxylation	acetoxylation	NOUN
biomedich-939	245	8	of	of	ADP
biomedich-939	245	9	2	2	NUM
biomedich-939	245	10	-	-	PUNCT
biomedich-939	245	11	aryloxyquinoline-3	aryloxyquinoline-3	NUM
biomedich-939	245	12	-	-	PUNCT
biomedich-939	245	13	carbaldehydes	carbaldehyde	NOUN
biomedich-939	245	14	.	.	PUNCT
biomedich-939	246	1	rsc	rsc	PROPN
biomedich-939	246	2	advances	advance	NOUN
biomedich-939	246	3	,	,	PUNCT
biomedich-939	246	4	14(19	14(19	NUM
biomedich-939	246	5	)	)	PUNCT
biomedich-939	246	6	,	,	PUNCT
biomedich-939	246	7	13306	13306	NUM
biomedich-939	246	8	-	-	SYM
biomedich-939	246	9	13310	13310	NUM
biomedich-939	246	10	.	.	PUNCT
biomedich-939	247	1	balaz	balaz	PROPN
biomedich-939	247	2	,	,	PUNCT
biomedich-939	247	3	s.	s.	PROPN
biomedich-939	247	4	(	(	PUNCT
biomedich-939	247	5	2009	2009	NUM
biomedich-939	247	6	)	)	PUNCT
biomedich-939	247	7	.	.	PUNCT
biomedich-939	248	1	modeling	model	VERB
biomedich-939	248	2	kinetics	kinetic	NOUN
biomedich-939	248	3	of	of	ADP
biomedich-939	248	4	subcellular	subcellular	ADJ
biomedich-939	248	5	disposition	disposition	NOUN
biomedich-939	248	6	of	of	ADP
biomedich-939	248	7	chemicals	chemical	NOUN
biomedich-939	248	8	.	.	PUNCT
biomedich-939	249	1	chemical	chemical	NOUN
biomedich-939	249	2	reviews	review	NOUN
biomedich-939	249	3	,	,	PUNCT
biomedich-939	249	4	109	109	NUM
biomedich-939	249	5	,	,	PUNCT
biomedich-939	249	6	1793–1899	1793–1899	NUM
biomedich-939	249	7	.	.	PUNCT
biomedich-939	250	1	belaidi	belaidi	PROPN
biomedich-939	250	2	,	,	PUNCT
biomedich-939	250	3	s.	s.	PROPN
biomedich-939	250	4	,	,	PUNCT
biomedich-939	250	5	belaidi	belaidi	PROPN
biomedich-939	250	6	,	,	PUNCT
biomedich-939	250	7	h.	h.	NOUN
biomedich-939	250	8	,	,	PUNCT
biomedich-939	250	9	kerassa	kerassa	PROPN
biomedich-939	250	10	,	,	PUNCT
biomedich-939	250	11	a.	a.	NOUN
biomedich-939	250	12	,	,	PUNCT
biomedich-939	250	13	saoula	saoula	NOUN
biomedich-939	250	14	,	,	PUNCT
biomedich-939	250	15	m.	m.	NOUN
biomedich-939	250	16	,	,	PUNCT
biomedich-939	250	17	&	&	CCONJ
biomedich-939	250	18	bouzidi	bouzidi	PROPN
biomedich-939	250	19	,	,	PUNCT
biomedich-939	250	20	d.	d.	PROPN
biomedich-939	250	21	(	(	PUNCT
biomedich-939	250	22	2016	2016	NUM
biomedich-939	250	23	)	)	PUNCT
biomedich-939	250	24	.	.	PUNCT
biomedich-939	251	1	predictive	predictive	ADJ
biomedich-939	251	2	qualitative	qualitative	ADJ
biomedich-939	251	3	structure	structure	NOUN
biomedich-939	251	4	-	-	PUNCT
biomedich-939	251	5	property	property	NOUN
biomedich-939	251	6	/	/	SYM
biomedich-939	251	7	activity	activity	NOUN
biomedich-939	251	8	relationships	relationship	NOUN
biomedich-939	251	9	for	for	ADP
biomedich-939	251	10	drug	drug	NOUN
biomedich-939	251	11	design	design	NOUN
biomedich-939	251	12	in	in	ADP
biomedich-939	251	13	some	some	PRON
biomedich-939	251	14	of	of	ADP
biomedich-939	251	15	antimycobacterial	antimycobacterial	ADJ
biomedich-939	251	16	pyrrole	pyrrole	ADJ
biomedich-939	251	17	derivatives	derivative	NOUN
biomedich-939	251	18	.	.	PUNCT
biomedich-939	252	1	quantum	quantum	ADJ
biomedich-939	252	2	matter	matter	NOUN
biomedich-939	252	3	,	,	PUNCT
biomedich-939	252	4	5	5	NUM
biomedich-939	252	5	,	,	PUNCT
biomedich-939	252	6	798–805	798–805	NUM
biomedich-939	252	7	.	.	PUNCT
biomedich-939	253	1	blume	blume	PROPN
biomedich-939	253	2	,	,	PUNCT
biomedich-939	253	3	a.	a.	NOUN
biomedich-939	253	4	,	,	PUNCT
biomedich-939	253	5	hübner	hübner	NOUN
biomedich-939	253	6	,	,	PUNCT
biomedich-939	253	7	w.	w.	PROPN
biomedich-939	253	8	,	,	PUNCT
biomedich-939	253	9	&	&	CCONJ
biomedich-939	253	10	messner	messner	PROPN
biomedich-939	253	11	,	,	PUNCT
biomedich-939	253	12	g.	g.	PROPN
biomedich-939	253	13	(	(	PUNCT
biomedich-939	253	14	1988	1988	NUM
biomedich-939	253	15	)	)	PUNCT
biomedich-939	253	16	.	.	PUNCT
biomedich-939	254	1	fourier	fourier	PROPN
biomedich-939	254	2	transform	transform	VERB
biomedich-939	254	3	infrared	infrared	ADJ
biomedich-939	254	4	spectroscopy	spectroscopy	NOUN
biomedich-939	254	5	of	of	ADP
biomedich-939	254	6	o	o	NOUN
biomedich-939	254	7	labeled	label	VERB
biomedich-939	254	8	phospholipids	phospholipid	NOUN
biomedich-939	254	9	hydrogen	hydrogen	NOUN
biomedich-939	254	10	bonding	bonding	NOUN
biomedich-939	254	11	to	to	ADP
biomedich-939	254	12	carbonyl	carbonyl	NOUN
biomedich-939	254	13	groups	group	NOUN
biomedich-939	254	14	.	.	PUNCT
biomedich-939	255	1	biochemistry	biochemistry	NOUN
biomedich-939	255	2	,	,	PUNCT
biomedich-939	255	3	27(21	27(21	NUM
biomedich-939	255	4	)	)	PUNCT
biomedich-939	255	5	,	,	PUNCT
biomedich-939	255	6	8239	8239	NUM
biomedich-939	255	7	-	-	SYM
biomedich-939	255	8	8249	8249	NUM
biomedich-939	255	9	.	.	PUNCT
biomedich-939	256	1	buddensiek	buddensiek	PROPN
biomedich-939	256	2	,	,	PUNCT
biomedich-939	256	3	d.	d.	PROPN
biomedich-939	256	4	,	,	PUNCT
biomedich-939	256	5	mlostoń	mlostoń	PROPN
biomedich-939	256	6	,	,	PUNCT
biomedich-939	256	7	g.	g.	PROPN
biomedich-939	256	8	,	,	PUNCT
biomedich-939	256	9	matczak	matczak	NOUN
biomedich-939	256	10	,	,	PUNCT
biomedich-939	256	11	p.	p.	PROPN
biomedich-939	256	12	,	,	PUNCT
biomedich-939	256	13	&	&	CCONJ
biomedich-939	256	14	voss	voss	PROPN
biomedich-939	256	15	,	,	PUNCT
biomedich-939	256	16	j.	j.	PROPN
biomedich-939	256	17	(	(	PUNCT
biomedich-939	256	18	2021	2021	NUM
biomedich-939	256	19	)	)	PUNCT
biomedich-939	256	20	.	.	PUNCT
biomedich-939	257	1	a	a	DET
biomedich-939	257	2	dft	dft	PROPN
biomedich-939	257	3	study	study	NOUN
biomedich-939	257	4	on	on	ADP
biomedich-939	257	5	the	the	DET
biomedich-939	257	6	mechanism	mechanism	NOUN
biomedich-939	257	7	of	of	ADP
biomedich-939	257	8	the	the	DET
biomedich-939	257	9	formation	formation	NOUN
biomedich-939	257	10	of	of	ADP
biomedich-939	257	11	1	1	NUM
biomedich-939	257	12	,	,	PUNCT
biomedich-939	257	13	4	4	NUM
biomedich-939	257	14	,	,	PUNCT
biomedich-939	257	15	2	2	NUM
biomedich-939	257	16	,	,	PUNCT
biomedich-939	257	17	3‐dithiadiazinanes	3‐dithiadiazinane	NOUN
biomedich-939	257	18	by	by	ADP
biomedich-939	257	19	head‐to‐head	head‐to‐head	PROPN
biomedich-939	257	20	[	[	X
biomedich-939	257	21	3	3	NUM
biomedich-939	257	22	+	+	NOUN
biomedich-939	257	23	3	3	NUM
biomedich-939	257	24	]	]	SYM
biomedich-939	257	25	cyclodimerization	cyclodimerization	NOUN
biomedich-939	257	26	of	of	ADP
biomedich-939	257	27	thiocarbonyl	thiocarbonyl	PROPN
biomedich-939	257	28	s‐imides	s‐imides	PROPN
biomedich-939	257	29	.	.	PUNCT
biomedich-939	257	30	journal	journal	PROPN
biomedich-939	257	31	of	of	ADP
biomedich-939	257	32	physical	physical	ADJ
biomedich-939	257	33	organic	organic	ADJ
biomedich-939	257	34	chemistry	chemistry	NOUN
biomedich-939	257	35	,	,	PUNCT
biomedich-939	257	36	34(4	34(4	NUM
biomedich-939	257	37	)	)	PUNCT
biomedich-939	257	38	,	,	PUNCT
biomedich-939	257	39	e4170	e4170	PROPN
biomedich-939	257	40	.	.	PUNCT
biomedich-939	258	1	gazquez	gazquez	PROPN
biomedich-939	258	2	,	,	PUNCT
biomedich-939	258	3	j.	j.	PROPN
biomedich-939	258	4	l.	l.	PROPN
biomedich-939	258	5	,	,	PUNCT
biomedich-939	258	6	vela	vela	PROPN
biomedich-939	258	7	,	,	PUNCT
biomedich-939	258	8	a.	a.	NOUN
biomedich-939	258	9	,	,	PUNCT
biomedich-939	258	10	guégan	guégan	NOUN
biomedich-939	258	11	,	,	PUNCT
biomedich-939	258	12	f.	f.	PROPN
biomedich-939	258	13	,	,	PUNCT
biomedich-939	258	14	&	&	CCONJ
biomedich-939	258	15	chermette	chermette	PROPN
biomedich-939	258	16	,	,	PUNCT
biomedich-939	258	17	h.	h.	PROPN
biomedich-939	258	18	(	(	PUNCT
biomedich-939	258	19	2014	2014	NUM
biomedich-939	258	20	)	)	PUNCT
biomedich-939	258	21	.	.	PUNCT
biomedich-939	259	1	revisiting	revisit	VERB
biomedich-939	259	2	electroaccepting	electroaccepte	VERB
biomedich-939	259	3	and	and	CCONJ
biomedich-939	259	4	electrodonating	electrodonate	VERB
biomedich-939	259	5	powers	power	NOUN
biomedich-939	259	6	:	:	PUNCT
biomedich-939	259	7	proposals	proposal	NOUN
biomedich-939	259	8	for	for	ADP
biomedich-939	259	9	local	local	ADJ
biomedich-939	259	10	electrophilicity	electrophilicity	NOUN
biomedich-939	259	11	and	and	CCONJ
biomedich-939	259	12	local	local	ADJ
biomedich-939	259	13	nucleophilicity	nucleophilicity	NOUN
biomedich-939	259	14	descriptors	descriptor	NOUN
biomedich-939	259	15	.	.	PUNCT
biomedich-939	260	1	physical	physical	ADJ
biomedich-939	260	2	chemistry	chemistry	NOUN
biomedich-939	260	3	chemical	chemical	PROPN
biomedich-939	260	4	physics	physics	PROPN
biomedich-939	260	5	,	,	PUNCT
biomedich-939	260	6	16(48	16(48	NUM
biomedich-939	260	7	)	)	PUNCT
biomedich-939	260	8	,	,	PUNCT
biomedich-939	260	9	26832–26842	26832–26842	NUM
biomedich-939	260	10	.	.	PUNCT
biomedich-939	260	11	czeczot	czeczot	PROPN
biomedich-939	260	12	,	,	PUNCT
biomedich-939	260	13	h.	h.	PROPN
biomedich-939	260	14	,	,	PUNCT
biomedich-939	260	15	tudek	tudek	PROPN
biomedich-939	260	16	,	,	PUNCT
biomedich-939	260	17	b.	b.	PROPN
biomedich-939	260	18	,	,	PUNCT
biomedich-939	260	19	kusztelak	kusztelak	PROPN
biomedich-939	260	20	,	,	PUNCT
biomedich-939	260	21	j.	j.	PROPN
biomedich-939	260	22	,	,	PUNCT
biomedich-939	260	23	szymczyk	szymczyk	PROPN
biomedich-939	260	24	,	,	PUNCT
biomedich-939	260	25	t.	t.	PROPN
biomedich-939	260	26	,	,	PUNCT
biomedich-939	260	27	dobrowolska	dobrowolska	PROPN
biomedich-939	260	28	,	,	PUNCT
biomedich-939	260	29	b.	b.	PROPN
biomedich-939	260	30	,	,	PUNCT
biomedich-939	260	31	glinkowska	glinkowska	PROPN
biomedich-939	260	32	,	,	PUNCT
biomedich-939	260	33	g.	g.	PROPN
biomedich-939	260	34	,	,	PUNCT
biomedich-939	260	35	&	&	CCONJ
biomedich-939	260	36	strzelecka	strzelecka	PROPN
biomedich-939	260	37	,	,	PUNCT
biomedich-939	260	38	h.	h.	PROPN
biomedich-939	260	39	(	(	PUNCT
biomedich-939	260	40	1990	1990	NUM
biomedich-939	260	41	)	)	PUNCT
biomedich-939	260	42	.	.	PUNCT
biomedich-939	261	1	isolation	isolation	NOUN
biomedich-939	261	2	and	and	CCONJ
biomedich-939	261	3	studies	study	NOUN
biomedich-939	261	4	of	of	ADP
biomedich-939	261	5	the	the	DET
biomedich-939	261	6	mutagenic	mutagenic	ADJ
biomedich-939	261	7	activity	activity	NOUN
biomedich-939	261	8	in	in	ADP
biomedich-939	261	9	the	the	DET
biomedich-939	261	10	ames	ames	PROPN
biomedich-939	261	11	test	test	NOUN
biomedich-939	261	12	of	of	ADP
biomedich-939	261	13	flavonoids	flavonoid	NOUN
biomedich-939	261	14	naturally	naturally	ADV
biomedich-939	261	15	occurring	occur	VERB
biomedich-939	261	16	in	in	ADP
biomedich-939	261	17	medical	medical	ADJ
biomedich-939	261	18	herbs	herb	NOUN
biomedich-939	261	19	.	.	PUNCT
biomedich-939	262	1	mutation	mutation	NOUN
biomedich-939	262	2	research	research	NOUN
biomedich-939	262	3	/	/	SYM
biomedich-939	262	4	genetic	genetic	ADJ
biomedich-939	262	5	toxicology	toxicology	NOUN
biomedich-939	262	6	,	,	PUNCT
biomedich-939	262	7	240(3	240(3	NUM
biomedich-939	262	8	)	)	PUNCT
biomedich-939	262	9	,	,	PUNCT
biomedich-939	262	10	209	209	NUM
biomedich-939	262	11	-	-	SYM
biomedich-939	262	12	216	216	NUM
biomedich-939	262	13	.	.	PUNCT
biomedich-939	263	1	demircioğlu	demircioğlu	PROPN
biomedich-939	263	2	,	,	PUNCT
biomedich-939	263	3	z.	z.	PROPN
biomedich-939	263	4	,	,	PUNCT
biomedich-939	263	5	kaştaş	kaştaş	PROPN
biomedich-939	263	6	,	,	PUNCT
biomedich-939	263	7	g.	g.	PROPN
biomedich-939	263	8	,	,	PUNCT
biomedich-939	263	9	kaştaş	kaştaş	NOUN
biomedich-939	263	10	,	,	PUNCT
biomedich-939	263	11	ç	ç	X
biomedich-939	263	12	.	.	PUNCT
biomedich-939	263	13	a.	a.	PROPN
biomedich-939	263	14	,	,	PUNCT
biomedich-939	263	15	&	&	CCONJ
biomedich-939	263	16	frank	frank	PROPN
biomedich-939	263	17	,	,	PUNCT
biomedich-939	263	18	r.	r.	PROPN
biomedich-939	263	19	(	(	PUNCT
biomedich-939	263	20	2019	2019	NUM
biomedich-939	263	21	)	)	PUNCT
biomedich-939	263	22	.	.	PUNCT
biomedich-939	264	1	spectroscopic	spectroscopic	NOUN
biomedich-939	264	2	,	,	PUNCT
biomedich-939	264	3	xrd	xrd	PROPN
biomedich-939	264	4	,	,	PUNCT
biomedich-939	264	5	hirshfeld	hirshfeld	PROPN
biomedich-939	264	6	surface	surface	PROPN
biomedich-939	264	7	and	and	CCONJ
biomedich-939	264	8	dft	dft	PROPN
biomedich-939	264	9	approach	approach	NOUN
biomedich-939	264	10	(	(	PUNCT
biomedich-939	264	11	chemical	chemical	NOUN
biomedich-939	264	12	activity	activity	NOUN
biomedich-939	264	13	,	,	PUNCT
biomedich-939	264	14	ect	ect	X
biomedich-939	264	15	,	,	PUNCT
biomedich-939	264	16	nbo	nbo	INTJ
biomedich-939	264	17	,	,	PUNCT
biomedich-939	264	18	ffa	ffa	PROPN
biomedich-939	264	19	,	,	PUNCT
biomedich-939	264	20	nlo	nlo	PROPN
biomedich-939	264	21	,	,	PUNCT
biomedich-939	264	22	mep	mep	PROPN
biomedich-939	264	23	,	,	PUNCT
biomedich-939	264	24	npa	npa	PROPN
biomedich-939	264	25	&	&	CCONJ
biomedich-939	264	26	mpa	mpa	PROPN
biomedich-939	264	27	)	)	PUNCT
biomedich-939	264	28	of	of	ADP
biomedich-939	264	29	(	(	PUNCT
biomedich-939	264	30	e)-4	e)-4	NOUN
biomedich-939	264	31	-	-	PUNCT
biomedich-939	264	32	bromo-2-[(4	bromo-2-[(4	NOUN
biomedich-939	264	33	-	-	PUNCT
biomedich-939	264	34	bromophenylimino	bromophenylimino	NOUN
biomedich-939	264	35	)	)	PUNCT
biomedich-939	264	36	methyl]-6ethoxyphenol	methyl]-6ethoxyphenol	PROPN
biomedich-939	264	37	.	.	PROPN
biomedich-939	264	38	journal	journal	NOUN
biomedich-939	264	39	of	of	ADP
biomedich-939	264	40	molecular	molecular	ADJ
biomedich-939	264	41	structure	structure	NOUN
biomedich-939	264	42	,	,	PUNCT
biomedich-939	264	43	1191	1191	NUM
biomedich-939	264	44	,	,	PUNCT
biomedich-939	264	45	129	129	NUM
biomedich-939	264	46	-	-	SYM
biomedich-939	264	47	137	137	NUM
biomedich-939	264	48	.	.	PUNCT
biomedich-939	265	1	di	di	PROPN
biomedich-939	265	2	,	,	PUNCT
biomedich-939	265	3	l.	l.	PROPN
biomedich-939	265	4	,	,	PUNCT
biomedich-939	265	5	&	&	CCONJ
biomedich-939	265	6	kerns	kerns	PROPN
biomedich-939	265	7	,	,	PUNCT
biomedich-939	265	8	e.	e.	PROPN
biomedich-939	265	9	h.	h.	PROPN
biomedich-939	265	10	(	(	PUNCT
biomedich-939	265	11	2015	2015	NUM
biomedich-939	265	12	)	)	PUNCT
biomedich-939	265	13	.	.	PUNCT
biomedich-939	266	1	drug	drug	NOUN
biomedich-939	266	2	-	-	PUNCT
biomedich-939	266	3	like	like	ADJ
biomedich-939	266	4	properties	property	NOUN
biomedich-939	266	5	:	:	PUNCT
biomedich-939	266	6	concepts	concept	NOUN
biomedich-939	266	7	,	,	PUNCT
biomedich-939	266	8	structure	structure	NOUN
biomedich-939	266	9	design	design	NOUN
biomedich-939	266	10	and	and	CCONJ
biomedich-939	266	11	methods	method	NOUN
biomedich-939	266	12	from	from	ADP
biomedich-939	266	13	adme	adme	NOUN
biomedich-939	266	14	to	to	ADP
biomedich-939	266	15	toxicity	toxicity	NOUN
biomedich-939	266	16	optimization	optimization	NOUN
biomedich-939	266	17	.	.	PUNCT
biomedich-939	267	1	academic	academic	ADJ
biomedich-939	267	2	press	press	PROPN
biomedich-939	267	3	,	,	PUNCT
biomedich-939	267	4	usa	usa	PROPN
biomedich-939	267	5	.	.	PROPN
biomedich-939	267	6	dib	dib	PROPN
biomedich-939	267	7	,	,	PUNCT
biomedich-939	267	8	m.	m.	NOUN
biomedich-939	267	9	,	,	PUNCT
biomedich-939	267	10	ouchetto	ouchetto	ADJ
biomedich-939	267	11	,	,	PUNCT
biomedich-939	267	12	h.	h.	PROPN
biomedich-939	267	13	,	,	PUNCT
biomedich-939	267	14	ouchetto	ouchetto	ADJ
biomedich-939	267	15	,	,	PUNCT
biomedich-939	267	16	k.	k.	PROPN
biomedich-939	267	17	,	,	PUNCT
biomedich-939	267	18	hafid	hafid	ADJ
biomedich-939	267	19	,	,	PUNCT
biomedich-939	267	20	a.	a.	NOUN
biomedich-939	267	21	,	,	PUNCT
biomedich-939	267	22	&	&	CCONJ
biomedich-939	267	23	khouili	khouili	NOUN
biomedich-939	267	24	,	,	PUNCT
biomedich-939	267	25	m.	m.	NOUN
biomedich-939	267	26	(	(	PUNCT
biomedich-939	267	27	2021	2021	NUM
biomedich-939	267	28	)	)	PUNCT
biomedich-939	267	29	.	.	PUNCT
biomedich-939	268	1	recent	recent	ADJ
biomedich-939	268	2	developments	development	NOUN
biomedich-939	268	3	of	of	ADP
biomedich-939	268	4	quinoline	quinoline	NOUN
biomedich-939	268	5	derivatives	derivative	NOUN
biomedich-939	268	6	and	and	CCONJ
biomedich-939	268	7	their	their	PRON
biomedich-939	268	8	potential	potential	ADJ
biomedich-939	268	9	biological	biological	ADJ
biomedich-939	268	10	activities	activity	NOUN
biomedich-939	268	11	.	.	PUNCT
biomedich-939	269	1	current	current	ADJ
biomedich-939	269	2	organic	organic	ADJ
biomedich-939	269	3	synthesis	synthesis	NOUN
biomedich-939	269	4	,	,	PUNCT
biomedich-939	269	5	18(3	18(3	NUM
biomedich-939	269	6	)	)	PUNCT
biomedich-939	269	7	,	,	PUNCT
biomedich-939	269	8	248	248	NUM
biomedich-939	269	9	-	-	SYM
biomedich-939	269	10	269	269	NUM
biomedich-939	269	11	.	.	PUNCT
biomedich-939	269	12	domingo	domingo	PROPN
biomedich-939	269	13	,	,	PUNCT
biomedich-939	269	14	l.	l.	PROPN
biomedich-939	269	15	r.	r.	PROPN
biomedich-939	269	16	,	,	PUNCT
biomedich-939	269	17	ríos	ríos	PROPN
biomedich-939	269	18	-	-	PUNCT
biomedich-939	269	19	gutiérrez	gutiérrez	NOUN
biomedich-939	269	20	,	,	PUNCT
biomedich-939	269	21	m.	m.	NOUN
biomedich-939	269	22	,	,	PUNCT
biomedich-939	269	23	&	&	CCONJ
biomedich-939	269	24	pérez	pérez	NOUN
biomedich-939	269	25	,	,	PUNCT
biomedich-939	269	26	p.	p.	NOUN
biomedich-939	269	27	(	(	PUNCT
biomedich-939	269	28	2016	2016	NUM
biomedich-939	269	29	)	)	PUNCT
biomedich-939	269	30	.	.	PUNCT
biomedich-939	270	1	applications	application	NOUN
biomedich-939	270	2	of	of	ADP
biomedich-939	270	3	the	the	DET
biomedich-939	270	4	conceptual	conceptual	ADJ
biomedich-939	270	5	density	density	NOUN
biomedich-939	270	6	functional	functional	ADJ
biomedich-939	270	7	theory	theory	NOUN
biomedich-939	270	8	indices	indice	VERB
biomedich-939	270	9	to	to	ADP
biomedich-939	270	10	organic	organic	ADJ
biomedich-939	270	11	chemistry	chemistry	NOUN
biomedich-939	270	12	reactivity	reactivity	NOUN
biomedich-939	270	13	.	.	PUNCT
biomedich-939	271	1	molecules	molecule	NOUN
biomedich-939	271	2	,	,	PUNCT
biomedich-939	271	3	21(6	21(6	NUM
biomedich-939	271	4	)	)	PUNCT
biomedich-939	271	5	,	,	PUNCT
biomedich-939	271	6	748	748	X
biomedich-939	271	7	.	.	PUNCT
biomedich-939	271	8	ennaba	ennaba	NOUN
biomedich-939	271	9	,	,	PUNCT
biomedich-939	271	10	a.	a.	NOUN
biomedich-939	271	11	m.	m.	PROPN
biomedich-939	271	12	a.	a.	PROPN
biomedich-939	271	13	s.	s.	PROPN
biomedich-939	271	14	(	(	PUNCT
biomedich-939	271	15	2017	2017	NUM
biomedich-939	271	16	)	)	PUNCT
biomedich-939	271	17	.	.	PUNCT
biomedich-939	272	1	theoretical	theoretical	ADJ
biomedich-939	272	2	study	study	NOUN
biomedich-939	272	3	of	of	ADP
biomedich-939	272	4	thiazole	thiazole	NOUN
biomedich-939	272	5	and	and	CCONJ
biomedich-939	272	6	some	some	PRON
biomedich-939	272	7	of	of	ADP
biomedich-939	272	8	its	its	PRON
biomedich-939	272	9	derivatives	derivative	NOUN
biomedich-939	272	10	in	in	ADP
biomedich-939	272	11	gas	gas	NOUN
biomedich-939	272	12	phase	phase	NOUN
biomedich-939	272	13	(	(	PUNCT
biomedich-939	272	14	doctoral	doctoral	ADJ
biomedich-939	272	15	dissertation	dissertation	NOUN
biomedich-939	272	16	)	)	PUNCT
biomedich-939	272	17	.	.	PUNCT
biomedich-939	273	1	aina	aina	PROPN
biomedich-939	273	2	et	et	PROPN
biomedich-939	273	3	al	al	PROPN
biomedich-939	273	4	.	.	PROPN
biomedich-939	273	5	–	–	PUNCT
biomedich-939	273	6	dft	dft	PROPN
biomedich-939	273	7	study	study	NOUN
biomedich-939	273	8	and	and	CCONJ
biomedich-939	273	9	admet	admet	PROPN
biomedich-939	273	10	investigation	investigation	NOUN
biomedich-939	273	11	of	of	ADP
biomedich-939	273	12	bioactive	bioactive	ADJ
biomedich-939	273	13	2	2	NUM
biomedich-939	273	14	-	-	PUNCT
biomedich-939	273	15	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	273	16	855	855	NUM
biomedich-939	273	17	fleming	fleming	NOUN
biomedich-939	273	18	,	,	PUNCT
biomedich-939	273	19	s.	s.	PROPN
biomedich-939	273	20	,	,	PUNCT
biomedich-939	273	21	mills	mill	NOUN
biomedich-939	273	22	,	,	PUNCT
biomedich-939	273	23	a.	a.	NOUN
biomedich-939	273	24	,	,	PUNCT
biomedich-939	273	25	&	&	CCONJ
biomedich-939	273	26	tuttle	tuttle	PROPN
biomedich-939	273	27	,	,	PUNCT
biomedich-939	273	28	t.	t.	PROPN
biomedich-939	273	29	(	(	PUNCT
biomedich-939	273	30	2011	2011	NUM
biomedich-939	273	31	)	)	PUNCT
biomedich-939	273	32	.	.	PUNCT
biomedich-939	274	1	predicting	predict	VERB
biomedich-939	274	2	the	the	DET
biomedich-939	274	3	uv	uv	NOUN
biomedich-939	274	4	–	–	PUNCT
biomedich-939	274	5	vis	vis	X
biomedich-939	274	6	spectra	spectra	NOUN
biomedich-939	274	7	of	of	ADP
biomedich-939	274	8	oxazine	oxazine	PROPN
biomedich-939	274	9	dyes	dye	NOUN
biomedich-939	274	10	.	.	PUNCT
biomedich-939	275	1	beilstein	beilstein	PROPN
biomedich-939	275	2	journal	journal	PROPN
biomedich-939	275	3	of	of	ADP
biomedich-939	275	4	organic	organic	ADJ
biomedich-939	275	5	chemistry	chemistry	NOUN
biomedich-939	275	6	,	,	PUNCT
biomedich-939	275	7	7(1	7(1	NUM
biomedich-939	275	8	)	)	PUNCT
biomedich-939	275	9	,	,	PUNCT
biomedich-939	275	10	432	432	NUM
biomedich-939	275	11	-	-	SYM
biomedich-939	275	12	441	441	NUM
biomedich-939	275	13	.	.	PUNCT
biomedich-939	276	1	frau	frau	PROPN
biomedich-939	276	2	,	,	PUNCT
biomedich-939	276	3	j.	j.	PROPN
biomedich-939	276	4	,	,	PUNCT
biomedich-939	276	5	&	&	CCONJ
biomedich-939	276	6	glossman	glossman	NOUN
biomedich-939	276	7	-	-	PUNCT
biomedich-939	276	8	mitnik	mitnik	NOUN
biomedich-939	276	9	,	,	PUNCT
biomedich-939	276	10	d.	d.	PROPN
biomedich-939	276	11	(	(	PUNCT
biomedich-939	276	12	2017	2017	NUM
biomedich-939	276	13	)	)	PUNCT
biomedich-939	276	14	.	.	PUNCT
biomedich-939	277	1	conceptual	conceptual	ADJ
biomedich-939	277	2	dft	dft	PROPN
biomedich-939	277	3	descriptors	descriptor	NOUN
biomedich-939	277	4	of	of	ADP
biomedich-939	277	5	amino	amino	ADJ
biomedich-939	277	6	acids	acid	NOUN
biomedich-939	277	7	with	with	ADP
biomedich-939	277	8	potential	potential	ADJ
biomedich-939	277	9	corrosion	corrosion	NOUN
biomedich-939	277	10	inhibition	inhibition	NOUN
biomedich-939	277	11	properties	property	NOUN
biomedich-939	277	12	calculated	calculate	VERB
biomedich-939	277	13	with	with	ADP
biomedich-939	277	14	the	the	DET
biomedich-939	277	15	latest	late	ADJ
biomedich-939	277	16	minnesota	minnesota	PROPN
biomedich-939	277	17	density	density	NOUN
biomedich-939	277	18	functionals	functional	NOUN
biomedich-939	277	19	.	.	PUNCT
biomedich-939	278	1	frontiers	frontier	NOUN
biomedich-939	278	2	in	in	ADP
biomedich-939	278	3	chemistry	chemistry	NOUN
biomedich-939	278	4	,	,	PUNCT
biomedich-939	278	5	5	5	NUM
biomedich-939	278	6	,	,	PUNCT
biomedich-939	278	7	16	16	NUM
biomedich-939	278	8	.	.	PUNCT
biomedich-939	278	9	galetin	galetin	PROPN
biomedich-939	278	10	,	,	PUNCT
biomedich-939	278	11	a.	a.	NOUN
biomedich-939	278	12	,	,	PUNCT
biomedich-939	278	13	ito	ito	PROPN
biomedich-939	278	14	,	,	PUNCT
biomedich-939	278	15	k.	k.	PROPN
biomedich-939	278	16	,	,	PUNCT
biomedich-939	278	17	hallifax	hallifax	PROPN
biomedich-939	278	18	,	,	PUNCT
biomedich-939	278	19	d.	d.	PROPN
biomedich-939	278	20	,	,	PUNCT
biomedich-939	278	21	&	&	CCONJ
biomedich-939	278	22	houston	houston	PROPN
biomedich-939	278	23	,	,	PUNCT
biomedich-939	278	24	j.	j.	PROPN
biomedich-939	278	25	b.	b.	PROPN
biomedich-939	278	26	(	(	PUNCT
biomedich-939	278	27	2005	2005	NUM
biomedich-939	278	28	)	)	PUNCT
biomedich-939	278	29	.	.	PUNCT
biomedich-939	279	1	cyp14	cyp14	NOUN
biomedich-939	279	2	substrate	substrate	NOUN
biomedich-939	279	3	selection	selection	NOUN
biomedich-939	279	4	and	and	CCONJ
biomedich-939	279	5	substitution	substitution	NOUN
biomedich-939	279	6	in	in	ADP
biomedich-939	279	7	the	the	DET
biomedich-939	279	8	prediction	prediction	NOUN
biomedich-939	279	9	of	of	ADP
biomedich-939	279	10	potential	potential	ADJ
biomedich-939	279	11	drug	drug	NOUN
biomedich-939	279	12	-	-	PUNCT
biomedich-939	279	13	drug	drug	NOUN
biomedich-939	279	14	interactions	interaction	NOUN
biomedich-939	279	15	.	.	PUNCT
biomedich-939	280	1	journal	journal	NOUN
biomedich-939	280	2	of	of	ADP
biomedich-939	280	3	pharmacology	pharmacology	NOUN
biomedich-939	280	4	and	and	CCONJ
biomedich-939	280	5	experimental	experimental	ADJ
biomedich-939	280	6	therapeutics	therapeutic	NOUN
biomedich-939	280	7	,	,	PUNCT
biomedich-939	280	8	314(1	314(1	NUM
biomedich-939	280	9	)	)	PUNCT
biomedich-939	280	10	,	,	PUNCT
biomedich-939	280	11	180	180	NUM
biomedich-939	280	12	-	-	SYM
biomedich-939	280	13	190	190	NUM
biomedich-939	280	14	.	.	PUNCT
biomedich-939	281	1	haroon	haroon	PROPN
biomedich-939	281	2	,	,	PUNCT
biomedich-939	281	3	m.	m.	NOUN
biomedich-939	281	4	,	,	PUNCT
biomedich-939	281	5	khalid	khalid	PROPN
biomedich-939	281	6	,	,	PUNCT
biomedich-939	281	7	m.	m.	NOUN
biomedich-939	281	8	,	,	PUNCT
biomedich-939	281	9	akhtar	akhtar	NOUN
biomedich-939	281	10	,	,	PUNCT
biomedich-939	281	11	t.	t.	PROPN
biomedich-939	281	12	,	,	PUNCT
biomedich-939	281	13	tahir	tahir	PROPN
biomedich-939	281	14	,	,	PUNCT
biomedich-939	281	15	m.	m.	NOUN
biomedich-939	281	16	n.	n.	PROPN
biomedich-939	281	17	,	,	PUNCT
biomedich-939	281	18	khan	khan	PROPN
biomedich-939	281	19	,	,	PUNCT
biomedich-939	281	20	m.	m.	NOUN
biomedich-939	281	21	u.	u.	PROPN
biomedich-939	281	22	,	,	PUNCT
biomedich-939	281	23	saleem	saleem	PROPN
biomedich-939	281	24	,	,	PUNCT
biomedich-939	281	25	m.	m.	NOUN
biomedich-939	281	26	,	,	PUNCT
biomedich-939	281	27	&	&	CCONJ
biomedich-939	281	28	jawaria	jawaria	PROPN
biomedich-939	281	29	,	,	PUNCT
biomedich-939	281	30	r.	r.	PROPN
biomedich-939	281	31	(	(	PUNCT
biomedich-939	281	32	2019	2019	NUM
biomedich-939	281	33	)	)	PUNCT
biomedich-939	281	34	.	.	PUNCT
biomedich-939	282	1	synthesis	synthesis	NOUN
biomedich-939	282	2	,	,	PUNCT
biomedich-939	282	3	spectroscopic	spectroscopic	NOUN
biomedich-939	282	4	,	,	PUNCT
biomedich-939	282	5	sc	sc	PROPN
biomedich-939	282	6	-	-	PUNCT
biomedich-939	282	7	xrd	xrd	PROPN
biomedich-939	282	8	characterizations	characterization	NOUN
biomedich-939	282	9	and	and	CCONJ
biomedich-939	282	10	dft	dft	PROPN
biomedich-939	282	11	based	base	VERB
biomedich-939	282	12	studies	study	NOUN
biomedich-939	282	13	of	of	ADP
biomedich-939	282	14	ethyl-2(substituted-(2	ethyl-2(substituted-(2	ADJ
biomedich-939	282	15	-	-	PUNCT
biomedich-939	282	16	benzylidenehydrazinyl))thiazole-4	benzylidenehydrazinyl))thiazole-4	NOUN
biomedich-939	282	17	-	-	PUNCT
biomedich-939	282	18	carboxylate	carboxylate	NOUN
biomedich-939	282	19	derivatives	derivative	NOUN
biomedich-939	282	20	.	.	PUNCT
biomedich-939	283	1	journal	journal	NOUN
biomedich-939	283	2	of	of	ADP
biomedich-939	283	3	molecular	molecular	ADJ
biomedich-939	283	4	structure	structure	NOUN
biomedich-939	283	5	,	,	PUNCT
biomedich-939	283	6	1187	1187	NUM
biomedich-939	283	7	,	,	PUNCT
biomedich-939	283	8	164	164	NUM
biomedich-939	283	9	-	-	SYM
biomedich-939	283	10	171	171	NUM
biomedich-939	283	11	.	.	PUNCT
biomedich-939	284	1	ho	ho	PROPN
biomedich-939	284	2	,	,	PUNCT
biomedich-939	284	3	j.	j.	PROPN
biomedich-939	284	4	,	,	PUNCT
biomedich-939	284	5	&	&	CCONJ
biomedich-939	284	6	ertem	ertem	PROPN
biomedich-939	284	7	,	,	PUNCT
biomedich-939	284	8	m.	m.	NOUN
biomedich-939	284	9	z.	z.	PROPN
biomedich-939	284	10	(	(	PUNCT
biomedich-939	284	11	2016	2016	NUM
biomedich-939	284	12	)	)	PUNCT
biomedich-939	284	13	.	.	PUNCT
biomedich-939	285	1	calculating	calculate	VERB
biomedich-939	285	2	free	free	ADJ
biomedich-939	285	3	energy	energy	NOUN
biomedich-939	285	4	changes	change	NOUN
biomedich-939	285	5	in	in	ADP
biomedich-939	285	6	continuum	continuum	ADJ
biomedich-939	285	7	solvation	solvation	NOUN
biomedich-939	285	8	models	model	NOUN
biomedich-939	285	9	.	.	PUNCT
biomedich-939	286	1	the	the	DET
biomedich-939	286	2	journal	journal	NOUN
biomedich-939	286	3	of	of	ADP
biomedich-939	286	4	physical	physical	ADJ
biomedich-939	286	5	chemistry	chemistry	NOUN
biomedich-939	286	6	b	b	NOUN
biomedich-939	286	7	,	,	PUNCT
biomedich-939	286	8	120(7	120(7	NUM
biomedich-939	286	9	)	)	PUNCT
biomedich-939	286	10	,	,	PUNCT
biomedich-939	286	11	1319	1319	NUM
biomedich-939	286	12	-	-	SYM
biomedich-939	286	13	1329	1329	NUM
biomedich-939	286	14	.	.	PUNCT
biomedich-939	287	1	islam	islam	PROPN
biomedich-939	287	2	,	,	PUNCT
biomedich-939	287	3	n.	n.	PROPN
biomedich-939	287	4	,	,	PUNCT
biomedich-939	287	5	&	&	CCONJ
biomedich-939	287	6	ghosh	ghosh	PROPN
biomedich-939	287	7	,	,	PUNCT
biomedich-939	287	8	d.	d.	PROPN
biomedich-939	287	9	c.	c.	PROPN
biomedich-939	287	10	(	(	PUNCT
biomedich-939	287	11	2011	2011	NUM
biomedich-939	287	12	)	)	PUNCT
biomedich-939	287	13	.	.	PUNCT
biomedich-939	288	1	the	the	DET
biomedich-939	288	2	electronegativity	electronegativity	NOUN
biomedich-939	288	3	and	and	CCONJ
biomedich-939	288	4	the	the	DET
biomedich-939	288	5	global	global	ADJ
biomedich-939	288	6	hardness	hardness	NOUN
biomedich-939	288	7	are	be	AUX
biomedich-939	288	8	periodic	periodic	ADJ
biomedich-939	288	9	properties	property	NOUN
biomedich-939	288	10	of	of	ADP
biomedich-939	288	11	atoms	atom	NOUN
biomedich-939	288	12	.	.	PUNCT
biomedich-939	289	1	journal	journal	NOUN
biomedich-939	289	2	of	of	ADP
biomedich-939	289	3	quantum	quantum	ADJ
biomedich-939	289	4	information	information	NOUN
biomedich-939	289	5	science	science	NOUN
biomedich-939	289	6	,	,	PUNCT
biomedich-939	289	7	1(3	1(3	NUM
biomedich-939	289	8	)	)	PUNCT
biomedich-939	289	9	,	,	PUNCT
biomedich-939	289	10	135	135	NUM
biomedich-939	289	11	.	.	X
biomedich-939	290	1	iwai	iwai	PROPN
biomedich-939	290	2	,	,	PUNCT
biomedich-939	290	3	t.	t.	PROPN
biomedich-939	290	4	,	,	PUNCT
biomedich-939	290	5	&	&	CCONJ
biomedich-939	290	6	sawamura	sawamura	PROPN
biomedich-939	290	7	,	,	PUNCT
biomedich-939	290	8	m.	m.	NOUN
biomedich-939	290	9	(	(	PUNCT
biomedich-939	290	10	2015	2015	NUM
biomedich-939	290	11	)	)	PUNCT
biomedich-939	290	12	.	.	PUNCT
biomedich-939	291	1	transition	transition	NOUN
biomedich-939	291	2	-	-	PUNCT
biomedich-939	291	3	metal	metal	NOUN
biomedich-939	291	4	-	-	PUNCT
biomedich-939	291	5	catalyzed	catalyze	VERB
biomedich-939	291	6	siteselective	siteselective	NOUN
biomedich-939	291	7	c	c	NOUN
biomedich-939	291	8	–	–	PUNCT
biomedich-939	291	9	h	h	NOUN
biomedich-939	291	10	functionalization	functionalization	NOUN
biomedich-939	291	11	of	of	ADP
biomedich-939	291	12	quinolines	quinoline	NOUN
biomedich-939	291	13	beyond	beyond	ADP
biomedich-939	291	14	c2	c2	PROPN
biomedich-939	291	15	selectivity	selectivity	NOUN
biomedich-939	291	16	.	.	PUNCT
biomedich-939	292	1	acs	acs	PROPN
biomedich-939	292	2	catalysis	catalysis	NOUN
biomedich-939	292	3	,	,	PUNCT
biomedich-939	292	4	5(9	5(9	NUM
biomedich-939	292	5	)	)	PUNCT
biomedich-939	292	6	,	,	PUNCT
biomedich-939	292	7	5031	5031	NUM
biomedich-939	292	8	-	-	SYM
biomedich-939	292	9	5040	5040	NUM
biomedich-939	292	10	.	.	PUNCT
biomedich-939	293	1	jain	jain	PROPN
biomedich-939	293	2	,	,	PUNCT
biomedich-939	293	3	s.	s.	PROPN
biomedich-939	293	4	v.	v.	PROPN
biomedich-939	293	5	,	,	PUNCT
biomedich-939	293	6	chandra	chandra	PROPN
biomedich-939	293	7	,	,	PUNCT
biomedich-939	293	8	p.	p.	PROPN
biomedich-939	293	9	,	,	PUNCT
biomedich-939	293	10	kumar	kumar	PROPN
biomedich-939	293	11	j.	j.	PROPN
biomedich-939	293	12	,	,	PUNCT
biomedich-939	293	13	pathak	pathak	PROPN
biomedich-939	293	14	,	,	PUNCT
biomedich-939	293	15	k.	k.	PROPN
biomedich-939	293	16	d.	d.	PROPN
biomedich-939	293	17	,	,	PUNCT
biomedich-939	293	18	pathak	pathak	PROPN
biomedich-939	293	19	,	,	PUNCT
biomedich-939	293	20	&	&	CCONJ
biomedich-939	293	21	a.	a.	PROPN
biomedich-939	293	22	v.	v.	PROPN
biomedich-939	293	23	(	(	PUNCT
biomedich-939	293	24	2016	2016	NUM
biomedich-939	293	25	)	)	PUNCT
biomedich-939	293	26	.	.	PUNCT
biomedich-939	294	1	comprehensive	comprehensive	ADJ
biomedich-939	294	2	review	review	NOUN
biomedich-939	294	3	on	on	ADP
biomedich-939	294	4	current	current	ADJ
biomedich-939	294	5	developments	development	NOUN
biomedich-939	294	6	of	of	ADP
biomedich-939	294	7	quinoline	quinoline	NOUN
biomedich-939	294	8	-	-	PUNCT
biomedich-939	294	9	based	base	VERB
biomedich-939	294	10	anticancer	anticancer	NOUN
biomedich-939	294	11	agents	agent	NOUN
biomedich-939	294	12	,	,	PUNCT
biomedich-939	294	13	arabian	arabian	ADJ
biomedich-939	294	14	journal	journal	NOUN
biomedich-939	294	15	of	of	ADP
biomedich-939	294	16	chemistry	chemistry	NOUN
biomedich-939	294	17	.	.	PUNCT
biomedich-939	295	1	jalan	jalan	PROPN
biomedich-939	295	2	,	,	PUNCT
biomedich-939	295	3	a.	a.	PROPN
biomedich-939	295	4	,	,	PUNCT
biomedich-939	295	5	ashcraft	ashcraft	PROPN
biomedich-939	295	6	,	,	PUNCT
biomedich-939	295	7	r.	r.	PROPN
biomedich-939	295	8	w.	w.	PROPN
biomedich-939	295	9	,	,	PUNCT
biomedich-939	295	10	west	west	PROPN
biomedich-939	295	11	,	,	PUNCT
biomedich-939	295	12	r.	r.	PROPN
biomedich-939	295	13	h.	h.	PROPN
biomedich-939	295	14	,	,	PUNCT
biomedich-939	295	15	&	&	CCONJ
biomedich-939	295	16	green	green	PROPN
biomedich-939	295	17	,	,	PUNCT
biomedich-939	295	18	w.	w.	PROPN
biomedich-939	295	19	h.	h.	PROPN
biomedich-939	295	20	(	(	PUNCT
biomedich-939	295	21	2010	2010	NUM
biomedich-939	295	22	)	)	PUNCT
biomedich-939	295	23	.	.	PUNCT
biomedich-939	296	1	predicting	predict	VERB
biomedich-939	296	2	solvation	solvation	NOUN
biomedich-939	296	3	energies	energy	NOUN
biomedich-939	296	4	for	for	ADP
biomedich-939	296	5	kinetic	kinetic	ADJ
biomedich-939	296	6	modelling	modelling	NOUN
biomedich-939	296	7	.	.	PUNCT
biomedich-939	297	1	annual	annual	ADJ
biomedich-939	297	2	reports	report	NOUN
biomedich-939	297	3	section	section	NOUN
biomedich-939	297	4	c	c	PROPN
biomedich-939	297	5	(	(	PUNCT
biomedich-939	297	6	physical	physical	ADJ
biomedich-939	297	7	chemistry	chemistry	NOUN
biomedich-939	297	8	)	)	PUNCT
biomedich-939	297	9	,	,	PUNCT
biomedich-939	297	10	106	106	NUM
biomedich-939	297	11	,	,	PUNCT
biomedich-939	297	12	211–258	211–258	NUM
biomedich-939	297	13	.	.	PUNCT
biomedich-939	298	1	janani	janani	PROPN
biomedich-939	298	2	,	,	PUNCT
biomedich-939	298	3	c.	c.	PROPN
biomedich-939	298	4	,	,	PUNCT
biomedich-939	298	5	&	&	CCONJ
biomedich-939	298	6	kumari	kumari	PROPN
biomedich-939	298	7	,	,	PUNCT
biomedich-939	298	8	b.	b.	PROPN
biomedich-939	298	9	r.	r.	PROPN
biomedich-939	298	10	(	(	PUNCT
biomedich-939	298	11	2015	2015	NUM
biomedich-939	298	12	)	)	PUNCT
biomedich-939	298	13	.	.	PUNCT
biomedich-939	299	1	ppar	ppar	NOUN
biomedich-939	299	2	gamma	gamma	PROPN
biomedich-939	299	3	gene	gene	NOUN
biomedich-939	299	4	–	–	PUNCT
biomedich-939	299	5	a	a	DET
biomedich-939	299	6	review	review	NOUN
biomedich-939	299	7	.	.	PUNCT
biomedich-939	300	1	diabetes	diabetes	NOUN
biomedich-939	300	2	&	&	CCONJ
biomedich-939	300	3	metabolic	metabolic	PROPN
biomedich-939	300	4	syndrome	syndrome	PROPN
biomedich-939	300	5	:	:	PUNCT
biomedich-939	300	6	clinical	clinical	ADJ
biomedich-939	300	7	research	research	NOUN
biomedich-939	300	8	&	&	CCONJ
biomedich-939	300	9	reviews	review	NOUN
biomedich-939	300	10	,	,	PUNCT
biomedich-939	300	11	9(1	9(1	NUM
biomedich-939	300	12	)	)	PUNCT
biomedich-939	300	13	,	,	PUNCT
biomedich-939	300	14	46	46	NUM
biomedich-939	300	15	-	-	SYM
biomedich-939	300	16	50	50	NUM
biomedich-939	300	17	.	.	PUNCT
biomedich-939	301	1	katayama	katayama	PROPN
biomedich-939	301	2	,	,	PUNCT
biomedich-939	301	3	r.	r.	PROPN
biomedich-939	301	4	,	,	PUNCT
biomedich-939	301	5	koike	koike	PROPN
biomedich-939	301	6	,	,	PUNCT
biomedich-939	301	7	s.	s.	PROPN
biomedich-939	301	8	,	,	PUNCT
biomedich-939	301	9	sato	sato	PROPN
biomedich-939	301	10	,	,	PUNCT
biomedich-939	301	11	s.	s.	PROPN
biomedich-939	301	12	,	,	PUNCT
biomedich-939	301	13	sugimoto	sugimoto	PROPN
biomedich-939	301	14	,	,	PUNCT
biomedich-939	301	15	y.	y.	PROPN
biomedich-939	301	16	,	,	PUNCT
biomedich-939	301	17	tsuruo	tsuruo	ADJ
biomedich-939	301	18	,	,	PUNCT
biomedich-939	301	19	t.	t.	PROPN
biomedich-939	301	20	,	,	PUNCT
biomedich-939	301	21	&	&	CCONJ
biomedich-939	301	22	fujita	fujita	PROPN
biomedich-939	301	23	,	,	PUNCT
biomedich-939	301	24	n.	n.	PROPN
biomedich-939	301	25	(	(	PUNCT
biomedich-939	301	26	2009	2009	NUM
biomedich-939	301	27	)	)	PUNCT
biomedich-939	301	28	.	.	PUNCT
biomedich-939	302	1	dofequidar	dofequidar	NOUN
biomedich-939	302	2	fumarate	fumarate	NOUN
biomedich-939	302	3	sensitizes	sensitize	VERB
biomedich-939	302	4	cancer	cancer	NOUN
biomedich-939	302	5	stem‐like	stem‐like	PROPN
biomedich-939	302	6	side	side	ADJ
biomedich-939	302	7	population	population	NOUN
biomedich-939	302	8	cells	cell	NOUN
biomedich-939	302	9	to	to	ADP
biomedich-939	302	10	chemotherapeutic	chemotherapeutic	ADJ
biomedich-939	302	11	drugs	drug	NOUN
biomedich-939	302	12	by	by	ADP
biomedich-939	302	13	inhibiting	inhibit	VERB
biomedich-939	302	14	abcg2	abcg2	NOUN
biomedich-939	302	15	/	/	SYM
biomedich-939	302	16	bcrp‐mediated	bcrp‐mediate	VERB
biomedich-939	302	17	drug	drug	NOUN
biomedich-939	302	18	export	export	NOUN
biomedich-939	302	19	.	.	PUNCT
biomedich-939	303	1	cancer	cancer	NOUN
biomedich-939	303	2	science	science	NOUN
biomedich-939	303	3	,	,	PUNCT
biomedich-939	303	4	100(11	100(11	NUM
biomedich-939	303	5	)	)	PUNCT
biomedich-939	303	6	,	,	PUNCT
biomedich-939	303	7	2060	2060	NUM
biomedich-939	303	8	-	-	SYM
biomedich-939	303	9	2068	2068	NUM
biomedich-939	303	10	.	.	PUNCT
biomedich-939	304	1	kodikara	kodikara	NOUN
biomedich-939	304	2	,	,	PUNCT
biomedich-939	304	3	m.	m.	NOUN
biomedich-939	304	4	s.	s.	PROPN
biomedich-939	304	5	,	,	PUNCT
biomedich-939	304	6	stranger	stranger	NOUN
biomedich-939	304	7	,	,	PUNCT
biomedich-939	304	8	r.	r.	PROPN
biomedich-939	304	9	,	,	PUNCT
biomedich-939	304	10	&	&	CCONJ
biomedich-939	304	11	humphrey	humphrey	PROPN
biomedich-939	304	12	,	,	PUNCT
biomedich-939	304	13	m.	m.	NOUN
biomedich-939	304	14	g.	g.	PROPN
biomedich-939	304	15	(	(	PUNCT
biomedich-939	304	16	2018	2018	NUM
biomedich-939	304	17	)	)	PUNCT
biomedich-939	304	18	.	.	PUNCT
biomedich-939	305	1	long‐range	long‐range	PROPN
biomedich-939	305	2	corrected	correct	VERB
biomedich-939	305	3	dft	dft	PROPN
biomedich-939	305	4	calculations	calculation	NOUN
biomedich-939	305	5	of	of	ADP
biomedich-939	305	6	first	first	ADJ
biomedich-939	305	7	hyperpolarizabilities	hyperpolarizabilitie	NOUN
biomedich-939	305	8	and	and	CCONJ
biomedich-939	305	9	excitation	excitation	NOUN
biomedich-939	305	10	energies	energy	NOUN
biomedich-939	305	11	of	of	ADP
biomedich-939	305	12	metal	metal	NOUN
biomedich-939	305	13	alkynyl	alkynyl	NOUN
biomedich-939	305	14	complexes	complex	NOUN
biomedich-939	305	15	.	.	PUNCT
biomedich-939	306	1	chemphyschem	chemphyschem	NOUN
biomedich-939	306	2	,	,	PUNCT
biomedich-939	306	3	19(12	19(12	NUM
biomedich-939	306	4	)	)	PUNCT
biomedich-939	306	5	,	,	PUNCT
biomedich-939	306	6	1537	1537	NUM
biomedich-939	306	7	-	-	SYM
biomedich-939	306	8	1546	1546	NUM
biomedich-939	306	9	.	.	PUNCT
biomedich-939	307	1	kouznetsov	kouznetsov	PROPN
biomedich-939	307	2	,	,	PUNCT
biomedich-939	307	3	v.	v.	ADP
biomedich-939	307	4	v.	v.	ADP
biomedich-939	307	5	,	,	PUNCT
biomedich-939	307	6	méndez	méndez	PROPN
biomedich-939	307	7	,	,	PUNCT
biomedich-939	307	8	l.	l.	PROPN
biomedich-939	307	9	y.	y.	PROPN
biomedich-939	307	10	v.	v.	PROPN
biomedich-939	307	11	,	,	PUNCT
biomedich-939	307	12	&	&	CCONJ
biomedich-939	307	13	gómez	gómez	NOUN
biomedich-939	307	14	,	,	PUNCT
biomedich-939	307	15	c.	c.	PROPN
biomedich-939	307	16	m.	m.	PROPN
biomedich-939	307	17	m.	m.	NOUN
biomedich-939	307	18	(	(	PUNCT
biomedich-939	307	19	2005	2005	NUM
biomedich-939	307	20	)	)	PUNCT
biomedich-939	307	21	.	.	PUNCT
biomedich-939	308	1	recent	recent	ADJ
biomedich-939	308	2	progress	progress	NOUN
biomedich-939	308	3	in	in	ADP
biomedich-939	308	4	the	the	DET
biomedich-939	308	5	synthesis	synthesis	NOUN
biomedich-939	308	6	of	of	ADP
biomedich-939	308	7	quinolines	quinoline	NOUN
biomedich-939	308	8	.	.	PUNCT
biomedich-939	309	1	current	current	ADJ
biomedich-939	309	2	organic	organic	ADJ
biomedich-939	309	3	chemistry	chemistry	NOUN
biomedich-939	309	4	,	,	PUNCT
biomedich-939	309	5	9(2	9(2	NUM
biomedich-939	309	6	)	)	PUNCT
biomedich-939	309	7	,	,	PUNCT
biomedich-939	309	8	141	141	NUM
biomedich-939	309	9	-	-	SYM
biomedich-939	309	10	161	161	NUM
biomedich-939	309	11	.	.	PUNCT
biomedich-939	310	1	kouznetsov	kouznetsov	PROPN
biomedich-939	310	2	,	,	PUNCT
biomedich-939	310	3	v.	v.	PROPN
biomedich-939	310	4	v.	v.	ADP
biomedich-939	310	5	,	,	PUNCT
biomedich-939	310	6	sojo	sojo	PROPN
biomedich-939	310	7	,	,	PUNCT
biomedich-939	310	8	f.	f.	PROPN
biomedich-939	310	9	,	,	PUNCT
biomedich-939	310	10	rojas	rojas	PROPN
biomedich-939	310	11	-	-	PUNCT
biomedich-939	310	12	ruiz	ruiz	NOUN
biomedich-939	310	13	,	,	PUNCT
biomedich-939	310	14	f.	f.	PROPN
biomedich-939	310	15	a.	a.	PROPN
biomedich-939	310	16	,	,	PUNCT
biomedich-939	310	17	merchan	merchan	PROPN
biomedich-939	310	18	-	-	PUNCT
biomedich-939	310	19	arenas	arenas	PROPN
biomedich-939	310	20	,	,	PUNCT
biomedich-939	310	21	d.	d.	PROPN
biomedich-939	310	22	r.	r.	PROPN
biomedich-939	310	23	,	,	PUNCT
biomedich-939	310	24	&	&	CCONJ
biomedich-939	310	25	arvelo	arvelo	PROPN
biomedich-939	310	26	,	,	PUNCT
biomedich-939	310	27	f.	f.	PROPN
biomedich-939	310	28	(	(	PUNCT
biomedich-939	310	29	2016	2016	NUM
biomedich-939	310	30	)	)	PUNCT
biomedich-939	310	31	.	.	PUNCT
biomedich-939	311	1	synthesis	synthesis	NOUN
biomedich-939	311	2	and	and	CCONJ
biomedich-939	311	3	cytotoxic	cytotoxic	ADJ
biomedich-939	311	4	evaluation	evaluation	NOUN
biomedich-939	311	5	of	of	ADP
biomedich-939	311	6	7	7	NUM
biomedich-939	311	7	-	-	PUNCT
biomedich-939	311	8	chloro-4	chloro-4	NOUN
biomedich-939	311	9	-	-	PUNCT
biomedich-939	311	10	phenoxyquinolines	phenoxyquinoline	NOUN
biomedich-939	311	11	with	with	ADP
biomedich-939	311	12	formyl	formyl	NOUN
biomedich-939	311	13	,	,	PUNCT
biomedich-939	311	14	oxime	oxime	NOUN
biomedich-939	311	15	and	and	CCONJ
biomedich-939	311	16	thiosemicarbazone	thiosemicarbazone	NOUN
biomedich-939	311	17	scaffolds	scaffold	NOUN
biomedich-939	311	18	.	.	PUNCT
biomedich-939	312	1	medicinal	medicinal	ADJ
biomedich-939	312	2	chemistry	chemistry	NOUN
biomedich-939	312	3	research	research	NOUN
biomedich-939	312	4	,	,	PUNCT
biomedich-939	312	5	25(11	25(11	NUM
biomedich-939	312	6	)	)	PUNCT
biomedich-939	312	7	,	,	PUNCT
biomedich-939	312	8	2718	2718	NUM
biomedich-939	312	9	-	-	SYM
biomedich-939	312	10	2727	2727	NUM
biomedich-939	312	11	.	.	PUNCT
biomedich-939	313	1	lea	lea	PROPN
biomedich-939	313	2	,	,	PUNCT
biomedich-939	313	3	t.	t.	PROPN
biomedich-939	313	4	(	(	PUNCT
biomedich-939	313	5	2015	2015	NUM
biomedich-939	313	6	)	)	PUNCT
biomedich-939	313	7	.	.	PUNCT
biomedich-939	314	1	caco-2	caco-2	NUM
biomedich-939	314	2	cell	cell	NOUN
biomedich-939	314	3	line	line	NOUN
biomedich-939	314	4	.	.	PUNCT
biomedich-939	315	1	in	in	ADP
biomedich-939	315	2	the	the	DET
biomedich-939	315	3	impact	impact	NOUN
biomedich-939	315	4	of	of	ADP
biomedich-939	315	5	food	food	NOUN
biomedich-939	315	6	bioactives	bioactive	VERB
biomedich-939	315	7	on	on	ADP
biomedich-939	315	8	health	health	NOUN
biomedich-939	315	9	(	(	PUNCT
biomedich-939	315	10	pp	pp	ADJ
biomedich-939	315	11	.	.	PUNCT
biomedich-939	316	1	103	103	NUM
biomedich-939	316	2	-	-	SYM
biomedich-939	316	3	111	111	NUM
biomedich-939	316	4	)	)	PUNCT
biomedich-939	316	5	.	.	PUNCT
biomedich-939	317	1	maldonado	maldonado	PROPN
biomedich-939	317	2	,	,	PUNCT
biomedich-939	317	3	a.	a.	NOUN
biomedich-939	317	4	m.	m.	NOUN
biomedich-939	317	5	,	,	PUNCT
biomedich-939	317	6	hagiwara	hagiwara	PROPN
biomedich-939	317	7	,	,	PUNCT
biomedich-939	317	8	s.	s.	PROPN
biomedich-939	317	9	,	,	PUNCT
biomedich-939	317	10	choi	choi	NOUN
biomedich-939	317	11	,	,	PUNCT
biomedich-939	317	12	t.	t.	PROPN
biomedich-939	317	13	h.	h.	PROPN
biomedich-939	317	14	,	,	PUNCT
biomedich-939	317	15	eckert	eckert	PROPN
biomedich-939	317	16	,	,	PUNCT
biomedich-939	317	17	f.	f.	PROPN
biomedich-939	317	18	,	,	PUNCT
biomedich-939	317	19	schwarz	schwarz	PROPN
biomedich-939	317	20	,	,	PUNCT
biomedich-939	317	21	k.	k.	PROPN
biomedich-939	317	22	,	,	PUNCT
biomedich-939	317	23	sundararaman	sundararaman	PROPN
biomedich-939	317	24	,	,	PUNCT
biomedich-939	317	25	r.	r.	PROPN
biomedich-939	317	26	,	,	PUNCT
biomedich-939	317	27	...	...	PUNCT
biomedich-939	317	28	&	&	CCONJ
biomedich-939	317	29	keith	keith	PROPN
biomedich-939	317	30	,	,	PUNCT
biomedich-939	317	31	j.	j.	PROPN
biomedich-939	317	32	a.	a.	PROPN
biomedich-939	317	33	(	(	PUNCT
biomedich-939	317	34	2021	2021	NUM
biomedich-939	317	35	)	)	PUNCT
biomedich-939	317	36	.	.	PUNCT
biomedich-939	318	1	quantifying	quantify	VERB
biomedich-939	318	2	uncertainties	uncertainty	NOUN
biomedich-939	318	3	in	in	ADP
biomedich-939	318	4	solvation	solvation	NOUN
biomedich-939	318	5	procedures	procedure	NOUN
biomedich-939	318	6	for	for	ADP
biomedich-939	318	7	modeling	model	VERB
biomedich-939	318	8	aqueous	aqueous	ADJ
biomedich-939	318	9	phase	phase	NOUN
biomedich-939	318	10	reaction	reaction	NOUN
biomedich-939	318	11	mechanisms	mechanism	NOUN
biomedich-939	318	12	.	.	PUNCT
biomedich-939	319	1	the	the	DET
biomedich-939	319	2	journal	journal	NOUN
biomedich-939	319	3	of	of	ADP
biomedich-939	319	4	physical	physical	ADJ
biomedich-939	319	5	chemistry	chemistry	NOUN
biomedich-939	319	6	a	a	PRON
biomedich-939	319	7	,	,	PUNCT
biomedich-939	319	8	125(1	125(1	NUM
biomedich-939	319	9	)	)	PUNCT
biomedich-939	319	10	,	,	PUNCT
biomedich-939	319	11	154	154	NUM
biomedich-939	319	12	-	-	SYM
biomedich-939	319	13	164	164	NUM
biomedich-939	319	14	.	.	PUNCT
biomedich-939	320	1	maurya	maurya	PROPN
biomedich-939	320	2	,	,	PUNCT
biomedich-939	320	3	v.	v.	PROPN
biomedich-939	320	4	k.	k.	PROPN
biomedich-939	320	5	,	,	PUNCT
biomedich-939	320	6	kumar	kumar	PROPN
biomedich-939	320	7	,	,	PUNCT
biomedich-939	320	8	s.	s.	PROPN
biomedich-939	320	9	,	,	PUNCT
biomedich-939	320	10	prasad	prasad	PROPN
biomedich-939	320	11	,	,	PUNCT
biomedich-939	320	12	a.	a.	PROPN
biomedich-939	320	13	k.	k.	PROPN
biomedich-939	320	14	,	,	PUNCT
biomedich-939	320	15	bhatt	bhatt	PROPN
biomedich-939	320	16	,	,	PUNCT
biomedich-939	320	17	m.	m.	PROPN
biomedich-939	320	18	l.	l.	PROPN
biomedich-939	320	19	,	,	PUNCT
biomedich-939	320	20	&	&	CCONJ
biomedich-939	320	21	saxena	saxena	PROPN
biomedich-939	320	22	,	,	PUNCT
biomedich-939	320	23	s.	s.	PROPN
biomedich-939	320	24	k.	k.	PROPN
biomedich-939	320	25	(	(	PUNCT
biomedich-939	320	26	2020	2020	NUM
biomedich-939	320	27	)	)	PUNCT
biomedich-939	320	28	.	.	PUNCT
biomedich-939	321	1	structure	structure	NOUN
biomedich-939	321	2	-	-	PUNCT
biomedich-939	321	3	based	base	VERB
biomedich-939	321	4	drug	drug	NOUN
biomedich-939	321	5	designing	design	VERB
biomedich-939	321	6	for	for	ADP
biomedich-939	321	7	potential	potential	ADJ
biomedich-939	321	8	antiviral	antiviral	ADJ
biomedich-939	321	9	activity	activity	NOUN
biomedich-939	321	10	of	of	ADP
biomedich-939	321	11	selected	select	VERB
biomedich-939	321	12	natural	natural	ADJ
biomedich-939	321	13	products	product	NOUN
biomedich-939	321	14	from	from	ADP
biomedich-939	321	15	ayurveda	ayurveda	NOUN
biomedich-939	321	16	against	against	ADP
biomedich-939	321	17	sars	sar	NOUN
biomedich-939	321	18	-	-	PUNCT
biomedich-939	321	19	cov-2	cov-2	NOUN
biomedich-939	321	20	spike	spike	ADJ
biomedich-939	321	21	glycoprotein	glycoprotein	NOUN
biomedich-939	321	22	and	and	CCONJ
biomedich-939	321	23	its	its	PRON
biomedich-939	321	24	cellular	cellular	ADJ
biomedich-939	321	25	receptor	receptor	NOUN
biomedich-939	321	26	.	.	PUNCT
biomedich-939	322	1	virusdisease	virusdisease	NOUN
biomedich-939	322	2	,	,	PUNCT
biomedich-939	322	3	31	31	NUM
biomedich-939	322	4	,	,	PUNCT
biomedich-939	322	5	179–193	179–193	NUM
biomedich-939	322	6	.	.	PUNCT
biomedich-939	323	1	mcginnity	mcginnity	NOUN
biomedich-939	323	2	,	,	PUNCT
biomedich-939	323	3	d.	d.	PROPN
biomedich-939	323	4	f.	f.	PROPN
biomedich-939	323	5	,	,	PUNCT
biomedich-939	323	6	collington	collington	PROPN
biomedich-939	323	7	,	,	PUNCT
biomedich-939	323	8	j.	j.	PROPN
biomedich-939	323	9	,	,	PUNCT
biomedich-939	323	10	austin	austin	PROPN
biomedich-939	323	11	,	,	PUNCT
biomedich-939	323	12	r.	r.	PROPN
biomedich-939	323	13	p.	p.	PROPN
biomedich-939	323	14	,	,	PUNCT
biomedich-939	323	15	&	&	CCONJ
biomedich-939	323	16	riley	riley	PROPN
biomedich-939	323	17	,	,	PUNCT
biomedich-939	323	18	r.	r.	PROPN
biomedich-939	323	19	j.	j.	PROPN
biomedich-939	323	20	(	(	PUNCT
biomedich-939	323	21	2007	2007	NUM
biomedich-939	323	22	)	)	PUNCT
biomedich-939	323	23	.	.	PUNCT
biomedich-939	324	1	evaluation	evaluation	NOUN
biomedich-939	324	2	of	of	ADP
biomedich-939	324	3	human	human	ADJ
biomedich-939	324	4	pharmacokinetics	pharmacokinetic	NOUN
biomedich-939	324	5	,	,	PUNCT
biomedich-939	324	6	therapeutic	therapeutic	ADJ
biomedich-939	324	7	dose	dose	NOUN
biomedich-939	324	8	and	and	CCONJ
biomedich-939	324	9	exposure	exposure	NOUN
biomedich-939	324	10	predictions	prediction	NOUN
biomedich-939	324	11	using	use	VERB
biomedich-939	324	12	marketed	market	VERB
biomedich-939	324	13	oral	oral	ADJ
biomedich-939	324	14	drugs	drug	NOUN
biomedich-939	324	15	.	.	PUNCT
biomedich-939	325	1	current	current	ADJ
biomedich-939	325	2	drug	drug	NOUN
biomedich-939	325	3	metabolism	metabolism	NOUN
biomedich-939	325	4	,	,	PUNCT
biomedich-939	325	5	8	8	NUM
biomedich-939	325	6	,	,	PUNCT
biomedich-939	325	7	463–479	463–479	NUM
biomedich-939	325	8	.	.	PUNCT
biomedich-939	326	1	meth	meth	NOUN
biomedich-939	326	2	-	-	PUNCT
biomedich-939	326	3	cohn	cohn	PROPN
biomedich-939	326	4	,	,	PUNCT
biomedich-939	326	5	o.	o.	PROPN
biomedich-939	326	6	,	,	PUNCT
biomedich-939	326	7	narine	narine	PROPN
biomedich-939	326	8	,	,	PUNCT
biomedich-939	326	9	b.	b.	PROPN
biomedich-939	326	10	,	,	PUNCT
biomedich-939	326	11	&	&	CCONJ
biomedich-939	326	12	tarnowski	tarnowski	PROPN
biomedich-939	326	13	,	,	PUNCT
biomedich-939	326	14	b.	b.	PROPN
biomedich-939	326	15	(	(	PUNCT
biomedich-939	326	16	1981	1981	NUM
biomedich-939	326	17	)	)	PUNCT
biomedich-939	326	18	.	.	PUNCT
biomedich-939	327	1	a	a	DET
biomedich-939	327	2	versatile	versatile	ADJ
biomedich-939	327	3	new	new	ADJ
biomedich-939	327	4	synthesis	synthesis	NOUN
biomedich-939	327	5	of	of	ADP
biomedich-939	327	6	quinolines	quinoline	NOUN
biomedich-939	327	7	and	and	CCONJ
biomedich-939	327	8	related	relate	VERB
biomedich-939	327	9	fused	fuse	VERB
biomedich-939	327	10	pyridines	pyridine	NOUN
biomedich-939	327	11	,	,	PUNCT
biomedich-939	327	12	part	part	NOUN
biomedich-939	327	13	5	5	NUM
biomedich-939	327	14	.	.	PUNCT
biomedich-939	328	1	the	the	DET
biomedich-939	328	2	synthesis	synthesis	NOUN
biomedich-939	328	3	of	of	ADP
biomedich-939	328	4	2	2	NUM
biomedich-939	328	5	-	-	PUNCT
biomedich-939	328	6	chloroquinoline-3	chloroquinoline-3	NUM
biomedich-939	328	7	-	-	PUNCT
biomedich-939	328	8	carbaldehydes	carbaldehyde	NOUN
biomedich-939	328	9	.	.	PUNCT
biomedich-939	329	1	journal	journal	NOUN
biomedich-939	329	2	of	of	ADP
biomedich-939	329	3	the	the	DET
biomedich-939	329	4	chemical	chemical	NOUN
biomedich-939	329	5	society	society	NOUN
biomedich-939	329	6	,	,	PUNCT
biomedich-939	329	7	perkin	perkin	PROPN
biomedich-939	329	8	transactions	transaction	NOUN
biomedich-939	329	9	1	1	NUM
biomedich-939	329	10	,	,	PUNCT
biomedich-939	329	11	1520	1520	NUM
biomedich-939	329	12	-	-	SYM
biomedich-939	329	13	1530	1530	NUM
biomedich-939	329	14	.	.	PUNCT
biomedich-939	330	1	meyer	meyer	PROPN
biomedich-939	330	2	,	,	PUNCT
biomedich-939	330	3	j.	j.	PROPN
biomedich-939	330	4	n.	n.	PROPN
biomedich-939	330	5	,	,	PUNCT
biomedich-939	330	6	hartman	hartman	PROPN
biomedich-939	330	7	,	,	PUNCT
biomedich-939	330	8	j.	j.	PROPN
biomedich-939	330	9	h.	h.	PROPN
biomedich-939	330	10	,	,	PUNCT
biomedich-939	330	11	&	&	CCONJ
biomedich-939	330	12	mello	mello	PROPN
biomedich-939	330	13	,	,	PUNCT
biomedich-939	330	14	d.	d.	PROPN
biomedich-939	330	15	f.	f.	PROPN
biomedich-939	330	16	(	(	PUNCT
biomedich-939	330	17	2018	2018	NUM
biomedich-939	330	18	)	)	PUNCT
biomedich-939	330	19	.	.	PUNCT
biomedich-939	331	1	mitochondrial	mitochondrial	ADJ
biomedich-939	331	2	toxicity	toxicity	NOUN
biomedich-939	331	3	.	.	PUNCT
biomedich-939	332	1	toxicological	toxicological	ADJ
biomedich-939	332	2	sciences	science	NOUN
biomedich-939	332	3	,	,	PUNCT
biomedich-939	332	4	162(1	162(1	NUM
biomedich-939	332	5	)	)	PUNCT
biomedich-939	332	6	,	,	PUNCT
biomedich-939	332	7	15	15	NUM
biomedich-939	332	8	-	-	SYM
biomedich-939	332	9	23	23	NUM
biomedich-939	332	10	.	.	PUNCT
biomedich-939	333	1	miar	miar	NOUN
biomedich-939	333	2	,	,	PUNCT
biomedich-939	333	3	m.	m.	NOUN
biomedich-939	333	4	,	,	PUNCT
biomedich-939	333	5	shiroudi	shiroudi	ADJ
biomedich-939	333	6	,	,	PUNCT
biomedich-939	333	7	a.	a.	NOUN
biomedich-939	333	8	,	,	PUNCT
biomedich-939	333	9	pourshamsian	pourshamsian	NOUN
biomedich-939	333	10	,	,	PUNCT
biomedich-939	333	11	k.	k.	PROPN
biomedich-939	333	12	,	,	PUNCT
biomedich-939	333	13	oliaey	oliaey	PROPN
biomedich-939	333	14	,	,	PUNCT
biomedich-939	333	15	a.	a.	PROPN
biomedich-939	333	16	r.	r.	PROPN
biomedich-939	333	17	,	,	PUNCT
biomedich-939	333	18	&	&	CCONJ
biomedich-939	333	19	hatamjafari	hatamjafari	PROPN
biomedich-939	333	20	,	,	PUNCT
biomedich-939	333	21	f.	f.	PROPN
biomedich-939	333	22	(	(	PUNCT
biomedich-939	333	23	2021	2021	NUM
biomedich-939	333	24	)	)	PUNCT
biomedich-939	333	25	.	.	PUNCT
biomedich-939	334	1	theoretical	theoretical	ADJ
biomedich-939	334	2	investigations	investigation	NOUN
biomedich-939	334	3	on	on	ADP
biomedich-939	334	4	the	the	DET
biomedich-939	334	5	homo	homo	NOUN
biomedich-939	334	6	–	–	PUNCT
biomedich-939	334	7	lumo	lumo	NOUN
biomedich-939	334	8	gap	gap	NOUN
biomedich-939	334	9	and	and	CCONJ
biomedich-939	334	10	global	global	ADJ
biomedich-939	334	11	reactivity	reactivity	NOUN
biomedich-939	334	12	descriptor	descriptor	NOUN
biomedich-939	334	13	studies	study	NOUN
biomedich-939	334	14	,	,	PUNCT
biomedich-939	334	15	natural	natural	ADJ
biomedich-939	334	16	bond	bond	NOUN
biomedich-939	334	17	orbital	orbital	NOUN
biomedich-939	334	18	,	,	PUNCT
biomedich-939	334	19	and	and	CCONJ
biomedich-939	334	20	nucleus	nucleus	NOUN
biomedich-939	334	21	-	-	PUNCT
biomedich-939	334	22	independent	independent	ADJ
biomedich-939	334	23	chemical	chemical	ADJ
biomedich-939	334	24	shifts	shift	NOUN
biomedich-939	334	25	analyses	analyse	VERB
biomedich-939	334	26	of	of	ADP
biomedich-939	334	27	3	3	NUM
biomedich-939	334	28	-	-	PUNCT
biomedich-939	334	29	phenylbenzo	phenylbenzo	NOUN
biomedich-939	334	30	[	[	X
biomedich-939	334	31	d	d	X
biomedich-939	334	32	]	]	X
biomedich-939	334	33	thiazole-2	thiazole-2	NUM
biomedich-939	334	34	(	(	PUNCT
biomedich-939	334	35	3	3	NUM
biomedich-939	334	36	h)-imine	h)-imine	NOUN
biomedich-939	334	37	and	and	CCONJ
biomedich-939	334	38	its	its	PRON
biomedich-939	334	39	para	para	NOUN
biomedich-939	334	40	-	-	PUNCT
biomedich-939	334	41	substituted	substitute	VERB
biomedich-939	334	42	derivatives	derivative	NOUN
biomedich-939	334	43	:	:	PUNCT
biomedich-939	334	44	solvent	solvent	ADJ
biomedich-939	334	45	and	and	CCONJ
biomedich-939	334	46	substituent	substituent	NOUN
biomedich-939	334	47	effects	effect	NOUN
biomedich-939	334	48	.	.	PUNCT
biomedich-939	335	1	journal	journal	PROPN
biomedich-939	335	2	of	of	ADP
biomedich-939	335	3	chemical	chemical	PROPN
biomedich-939	335	4	research	research	NOUN
biomedich-939	335	5	,	,	PUNCT
biomedich-939	335	6	45(1	45(1	NOUN
biomedich-939	335	7	-	-	PUNCT
biomedich-939	335	8	2	2	NUM
biomedich-939	335	9	)	)	PUNCT
biomedich-939	335	10	,	,	PUNCT
biomedich-939	335	11	147	147	NUM
biomedich-939	335	12	-	-	SYM
biomedich-939	335	13	158	158	NUM
biomedich-939	335	14	.	.	PUNCT
biomedich-939	336	1	neese	neese	PROPN
biomedich-939	336	2	,	,	PUNCT
biomedich-939	336	3	f.	f.	PROPN
biomedich-939	336	4	(	(	PUNCT
biomedich-939	336	5	2017	2017	NUM
biomedich-939	336	6	)	)	PUNCT
biomedich-939	336	7	.	.	PUNCT
biomedich-939	337	1	software	software	NOUN
biomedich-939	337	2	update	update	NOUN
biomedich-939	337	3	:	:	PUNCT
biomedich-939	337	4	the	the	DET
biomedich-939	337	5	orca	orca	NOUN
biomedich-939	337	6	program	program	NOUN
biomedich-939	337	7	system	system	NOUN
biomedich-939	337	8	,	,	PUNCT
biomedich-939	337	9	version	version	NOUN
biomedich-939	337	10	4.0	4.0	NUM
biomedich-939	337	11	.	.	PUNCT
biomedich-939	338	1	wiley	wiley	PROPN
biomedich-939	338	2	interdisciplinary	interdisciplinary	ADJ
biomedich-939	338	3	reviews	review	NOUN
biomedich-939	338	4	-	-	PUNCT
biomedich-939	338	5	computational	computational	ADJ
biomedich-939	338	6	molecular	molecular	ADJ
biomedich-939	338	7	science	science	NOUN
biomedich-939	338	8	,	,	PUNCT
biomedich-939	338	9	8(1	8(1	NOUN
biomedich-939	338	10	)	)	PUNCT
biomedich-939	338	11	,	,	PUNCT
biomedich-939	338	12	73	73	NUM
biomedich-939	338	13	-	-	SYM
biomedich-939	338	14	78	78	NUM
biomedich-939	338	15	.	.	PUNCT
biomedich-939	339	1	nithiyanantham	nithiyanantham	PROPN
biomedich-939	339	2	,	,	PUNCT
biomedich-939	339	3	s.	s.	PROPN
biomedich-939	339	4	,	,	PUNCT
biomedich-939	339	5	palaniappan	palaniappan	PROPN
biomedich-939	339	6	,	,	PUNCT
biomedich-939	339	7	l.	l.	PROPN
biomedich-939	339	8	,	,	PUNCT
biomedich-939	339	9	&	&	CCONJ
biomedich-939	339	10	lenin	lenin	PROPN
biomedich-939	339	11	,	,	PUNCT
biomedich-939	339	12	m.	m.	NOUN
biomedich-939	339	13	(	(	PUNCT
biomedich-939	339	14	2015	2015	NUM
biomedich-939	339	15	)	)	PUNCT
biomedich-939	339	16	.	.	PUNCT
biomedich-939	340	1	physicochemical	physicochemical	ADJ
biomedich-939	340	2	and	and	CCONJ
biomedich-939	340	3	bio	bio	ADJ
biomedich-939	340	4	-	-	ADJ
biomedich-939	340	5	chemical	chemical	ADJ
biomedich-939	340	6	nature	nature	NOUN
biomedich-939	340	7	of	of	ADP
biomedich-939	340	8	pectin	pectin	NOUN
biomedich-939	340	9	with	with	ADP
biomedich-939	340	10	amylase	amylase	NOUN
biomedich-939	340	11	s.	s.	PROPN
biomedich-939	340	12	journal	journal	PROPN
biomedich-939	340	13	of	of	ADP
biomedich-939	340	14	bionanoscience	bionanoscience	NOUN
biomedich-939	340	15	,	,	PUNCT
biomedich-939	340	16	9	9	NUM
biomedich-939	340	17	,	,	PUNCT
biomedich-939	340	18	359–362	359–362	NUM
biomedich-939	340	19	.	.	PUNCT
biomedich-939	341	1	nizar	nizar	PROPN
biomedich-939	341	2	,	,	PUNCT
biomedich-939	341	3	n.	n.	PROPN
biomedich-939	341	4	s.	s.	PROPN
biomedich-939	341	5	,	,	PUNCT
biomedich-939	341	6	sujith	sujith	PROPN
biomedich-939	341	7	,	,	PUNCT
biomedich-939	341	8	m.	m.	NOUN
biomedich-939	341	9	,	,	PUNCT
biomedich-939	341	10	swathi	swathi	PROPN
biomedich-939	341	11	,	,	PUNCT
biomedich-939	341	12	k.	k.	PROPN
biomedich-939	341	13	,	,	PUNCT
biomedich-939	341	14	sissa	sissa	PROPN
biomedich-939	341	15	,	,	PUNCT
biomedich-939	341	16	c.	c.	PROPN
biomedich-939	341	17	,	,	PUNCT
biomedich-939	341	18	painelli	painelli	PROPN
biomedich-939	341	19	,	,	PUNCT
biomedich-939	341	20	a.	a.	PROPN
biomedich-939	341	21	,	,	PUNCT
biomedich-939	341	22	&	&	CCONJ
biomedich-939	341	23	thomas	thomas	PROPN
biomedich-939	341	24	,	,	PUNCT
biomedich-939	341	25	k.	k.	PROPN
biomedich-939	341	26	g.	g.	PROPN
biomedich-939	341	27	(	(	PUNCT
biomedich-939	341	28	2021	2021	NUM
biomedich-939	341	29	)	)	PUNCT
biomedich-939	341	30	.	.	PUNCT
biomedich-939	342	1	emergent	emergent	VERB
biomedich-939	342	2	chiroptical	chiroptical	ADJ
biomedich-939	342	3	properties	property	NOUN
biomedich-939	342	4	in	in	ADP
biomedich-939	342	5	supramolecular	supramolecular	ADJ
biomedich-939	342	6	and	and	CCONJ
biomedich-939	342	7	plasmonic	plasmonic	ADJ
biomedich-939	342	8	assemblies	assembly	NOUN
biomedich-939	342	9	.	.	PUNCT
biomedich-939	343	1	chemical	chemical	ADJ
biomedich-939	343	2	society	society	NOUN
biomedich-939	343	3	reviews	review	NOUN
biomedich-939	343	4	,	,	PUNCT
biomedich-939	343	5	50(20	50(20	NUM
biomedich-939	343	6	)	)	PUNCT
biomedich-939	343	7	,	,	PUNCT
biomedich-939	343	8	11208	11208	NUM
biomedich-939	343	9	-	-	SYM
biomedich-939	343	10	11226	11226	NUM
biomedich-939	343	11	.	.	PUNCT
biomedich-939	344	1	kumar	kumar	PROPN
biomedich-939	344	2	,	,	PUNCT
biomedich-939	344	3	n.	n.	PROPN
biomedich-939	344	4	,	,	PUNCT
biomedich-939	344	5	mishra	mishra	PROPN
biomedich-939	344	6	,	,	PUNCT
biomedich-939	344	7	s.	s.	PROPN
biomedich-939	344	8	s.	s.	PROPN
biomedich-939	344	9	,	,	PUNCT
biomedich-939	344	10	sharma	sharma	PROPN
biomedich-939	344	11	,	,	PUNCT
biomedich-939	344	12	c.	c.	PROPN
biomedich-939	344	13	s.	s.	PROPN
biomedich-939	344	14	,	,	PUNCT
biomedich-939	344	15	singh	singh	PROPN
biomedich-939	344	16	,	,	PUNCT
biomedich-939	344	17	h.	h.	PROPN
biomedich-939	344	18	p.	p.	PROPN
biomedich-939	344	19	,	,	PUNCT
biomedich-939	344	20	&	&	CCONJ
biomedich-939	344	21	singh	singh	PROPN
biomedich-939	344	22	,	,	PUNCT
biomedich-939	344	23	h.	h.	PROPN
biomedich-939	344	24	(	(	PUNCT
biomedich-939	344	25	2017	2017	NUM
biomedich-939	344	26	)	)	PUNCT
biomedich-939	344	27	.	.	PUNCT
biomedich-939	345	1	in	in	ADP
biomedich-939	345	2	silico	silico	NOUN
biomedich-939	345	3	pharmacokinetic	pharmacokinetic	NOUN
biomedich-939	345	4	,	,	PUNCT
biomedich-939	345	5	bioactivity	bioactivity	NOUN
biomedich-939	345	6	and	and	CCONJ
biomedich-939	345	7	toxicity	toxicity	NOUN
biomedich-939	345	8	evaluation	evaluation	NOUN
biomedich-939	345	9	of	of	ADP
biomedich-939	345	10	some	some	DET
biomedich-939	345	11	selected	select	VERB
biomedich-939	345	12	anti	anti	ADJ
biomedich-939	345	13	-	-	ADJ
biomedich-939	345	14	ulcer	ulcer	ADJ
biomedich-939	345	15	agents	agent	NOUN
biomedich-939	345	16	.	.	PUNCT
biomedich-939	346	1	international	international	ADJ
biomedich-939	346	2	journal	journal	PROPN
biomedich-939	346	3	of	of	ADP
biomedich-939	346	4	pharmaceutical	pharmaceutical	PROPN
biomedich-939	346	5	sciences	sciences	PROPN
biomedich-939	346	6	review	review	NOUN
biomedich-939	346	7	and	and	CCONJ
biomedich-939	346	8	research	research	NOUN
biomedich-939	346	9	,	,	PUNCT
biomedich-939	346	10	9(2	9(2	NUM
biomedich-939	346	11	)	)	PUNCT
biomedich-939	346	12	,	,	PUNCT
biomedich-939	346	13	68	68	NUM
biomedich-939	346	14	-	-	SYM
biomedich-939	346	15	71	71	NUM
biomedich-939	346	16	.	.	PUNCT
biomedich-939	347	1	ozdemir	ozdemir	PROPN
biomedich-939	347	2	,	,	PUNCT
biomedich-939	347	3	l.	l.	PROPN
biomedich-939	347	4	,	,	PUNCT
biomedich-939	347	5	&	&	CCONJ
biomedich-939	347	6	sadoglu	sadoglu	PROPN
biomedich-939	347	7	,	,	PUNCT
biomedich-939	347	8	m.	m.	NOUN
biomedich-939	347	9	s.	s.	PROPN
biomedich-939	347	10	(	(	PUNCT
biomedich-939	347	11	2018	2018	NUM
biomedich-939	347	12	)	)	PUNCT
biomedich-939	347	13	.	.	PUNCT
biomedich-939	348	1	m1	m1	PROPN
biomedich-939	348	2	and	and	CCONJ
biomedich-939	348	3	e2	e2	PROPN
biomedich-939	348	4	transitions	transition	NOUN
biomedich-939	348	5	in	in	ADP
biomedich-939	348	6	the	the	DET
biomedich-939	348	7	ground	ground	NOUN
biomedich-939	348	8	-	-	PUNCT
biomedich-939	348	9	state	state	NOUN
biomedich-939	348	10	levels	level	NOUN
biomedich-939	348	11	of	of	ADP
biomedich-939	348	12	neutral	neutral	ADJ
biomedich-939	348	13	tin	tin	NOUN
biomedich-939	348	14	.	.	PUNCT
biomedich-939	349	1	poole	poole	PROPN
biomedich-939	349	2	,	,	PUNCT
biomedich-939	349	3	s.	s.	PROPN
biomedich-939	349	4	k.	k.	PROPN
biomedich-939	349	5	,	,	PUNCT
biomedich-939	349	6	&	&	CCONJ
biomedich-939	349	7	poole	poole	PROPN
biomedich-939	349	8	,	,	PUNCT
biomedich-939	349	9	c.	c.	PROPN
biomedich-939	349	10	f.	f.	PROPN
biomedich-939	349	11	(	(	PUNCT
biomedich-939	349	12	2003	2003	NUM
biomedich-939	349	13	)	)	PUNCT
biomedich-939	349	14	.	.	PUNCT
biomedich-939	350	1	separation	separation	NOUN
biomedich-939	350	2	methods	method	NOUN
biomedich-939	350	3	for	for	ADP
biomedich-939	350	4	estimating	estimate	VERB
biomedich-939	350	5	octanol	octanol	NOUN
biomedich-939	350	6	–	–	PUNCT
biomedich-939	350	7	water	water	NOUN
biomedich-939	350	8	partition	partition	NOUN
biomedich-939	350	9	coefficients	coefficient	NOUN
biomedich-939	350	10	.	.	PUNCT
biomedich-939	351	1	journal	journal	NOUN
biomedich-939	351	2	of	of	ADP
biomedich-939	351	3	chromatography	chromatography	PROPN
biomedich-939	351	4	b	b	PROPN
biomedich-939	351	5	,	,	PUNCT
biomedich-939	351	6	797	797	NUM
biomedich-939	351	7	,	,	PUNCT
biomedich-939	351	8	3–19	3–19	NOUN
biomedich-939	351	9	.	.	PUNCT
biomedich-939	352	1	ramírez	ramírez	PROPN
biomedich-939	352	2	,	,	PUNCT
biomedich-939	352	3	h.	h.	PROPN
biomedich-939	352	4	,	,	PUNCT
biomedich-939	352	5	fernandez	fernandez	PROPN
biomedich-939	352	6	-	-	PUNCT
biomedich-939	352	7	moreira	moreira	PROPN
biomedich-939	352	8	,	,	PUNCT
biomedich-939	352	9	e.	e.	PROPN
biomedich-939	352	10	,	,	PUNCT
biomedich-939	352	11	rodrigues	rodrigues	PROPN
biomedich-939	352	12	,	,	PUNCT
biomedich-939	352	13	j.	j.	PROPN
biomedich-939	352	14	r.	r.	PROPN
biomedich-939	352	15	,	,	PUNCT
biomedich-939	352	16	mijares	mijares	PROPN
biomedich-939	352	17	,	,	PUNCT
biomedich-939	352	18	m.	m.	PROPN
biomedich-939	352	19	r.	r.	PROPN
biomedich-939	352	20	,	,	PUNCT
biomedich-939	352	21	ángel	ángel	PROPN
biomedich-939	352	22	,	,	PUNCT
biomedich-939	352	23	j.	j.	PROPN
biomedich-939	352	24	e.	e.	PROPN
biomedich-939	352	25	,	,	PUNCT
biomedich-939	352	26	&	&	CCONJ
biomedich-939	352	27	charris	charris	PROPN
biomedich-939	352	28	,	,	PUNCT
biomedich-939	352	29	j.	j.	PROPN
biomedich-939	352	30	e.	e.	PROPN
biomedich-939	352	31	(	(	PUNCT
biomedich-939	352	32	2022	2022	NUM
biomedich-939	352	33	)	)	PUNCT
biomedich-939	352	34	.	.	PUNCT
biomedich-939	353	1	synthesis	synthesis	NOUN
biomedich-939	353	2	and	and	CCONJ
biomedich-939	353	3	in	in	ADP
biomedich-939	353	4	silico	silico	NOUN
biomedich-939	353	5	adme	adme	NOUN
biomedich-939	353	6	/	/	SYM
biomedich-939	353	7	tox	tox	NOUN
biomedich-939	353	8	profiling	profiling	NOUN
biomedich-939	353	9	studies	study	NOUN
biomedich-939	353	10	of	of	ADP
biomedich-939	353	11	heterocyclic	heterocyclic	ADJ
biomedich-939	353	12	hybrids	hybrid	NOUN
biomedich-939	353	13	based	base	VERB
biomedich-939	353	14	on	on	ADP
biomedich-939	353	15	chloroquine	chloroquine	NOUN
biomedich-939	353	16	scaffolds	scaffold	NOUN
biomedich-939	353	17	with	with	ADP
biomedich-939	353	18	potential	potential	ADJ
biomedich-939	353	19	antimalarial	antimalarial	ADJ
biomedich-939	353	20	activity	activity	NOUN
biomedich-939	353	21	.	.	PUNCT
biomedich-939	354	1	parasitology	parasitology	NOUN
biomedich-939	354	2	research	research	NOUN
biomedich-939	354	3	,	,	PUNCT
biomedich-939	354	4	121(1	121(1	NUM
biomedich-939	354	5	)	)	PUNCT
biomedich-939	354	6	,	,	PUNCT
biomedich-939	354	7	441	441	NUM
biomedich-939	354	8	-	-	SYM
biomedich-939	354	9	451	451	NUM
biomedich-939	354	10	.	.	PUNCT
biomedich-939	355	1	ramešová	ramešová	PROPN
biomedich-939	355	2	,	,	PUNCT
biomedich-939	355	3	š	š	PROPN
biomedich-939	355	4	.	.	PROPN
biomedich-939	355	5	,	,	PUNCT
biomedich-939	355	6	sokolová	sokolová	PROPN
biomedich-939	355	7	,	,	PUNCT
biomedich-939	355	8	r.	r.	PROPN
biomedich-939	355	9	,	,	PUNCT
biomedich-939	355	10	degano	degano	PROPN
biomedich-939	355	11	,	,	PUNCT
biomedich-939	355	12	i.	i.	NOUN
biomedich-939	355	13	,	,	PUNCT
biomedich-939	355	14	bulíčková	bulíčková	PROPN
biomedich-939	355	15	,	,	PUNCT
biomedich-939	355	16	j.	j.	PROPN
biomedich-939	355	17	,	,	PUNCT
biomedich-939	355	18	žabka	žabka	PROPN
biomedich-939	355	19	,	,	PUNCT
biomedich-939	355	20	j.	j.	PROPN
biomedich-939	355	21	,	,	PUNCT
biomedich-939	355	22	&	&	CCONJ
biomedich-939	355	23	gál	gál	PROPN
biomedich-939	355	24	,	,	PUNCT
biomedich-939	355	25	m.	m.	NOUN
biomedich-939	355	26	(	(	PUNCT
biomedich-939	355	27	2012	2012	NUM
biomedich-939	355	28	)	)	PUNCT
biomedich-939	355	29	.	.	PUNCT
biomedich-939	356	1	on	on	ADP
biomedich-939	356	2	the	the	DET
biomedich-939	356	3	stability	stability	NOUN
biomedich-939	356	4	of	of	ADP
biomedich-939	356	5	the	the	DET
biomedich-939	356	6	bioactive	bioactive	ADJ
biomedich-939	356	7	flavonoids	flavonoid	NOUN
biomedich-939	356	8	quercetin	quercetin	NOUN
biomedich-939	356	9	and	and	CCONJ
biomedich-939	356	10	luteolin	luteolin	PROPN
biomedich-939	356	11	under	under	ADP
biomedich-939	356	12	oxygen	oxygen	NOUN
biomedich-939	356	13	-	-	PUNCT
biomedich-939	356	14	free	free	ADJ
biomedich-939	356	15	conditions	condition	NOUN
biomedich-939	356	16	.	.	PUNCT
biomedich-939	357	1	analytical	analytical	ADJ
biomedich-939	357	2	and	and	CCONJ
biomedich-939	357	3	bioanalytical	bioanalytical	ADJ
biomedich-939	357	4	chemistry	chemistry	NOUN
biomedich-939	357	5	,	,	PUNCT
biomedich-939	357	6	402(2	402(2	NUM
biomedich-939	357	7	)	)	PUNCT
biomedich-939	357	8	,	,	PUNCT
biomedich-939	357	9	975	975	NUM
biomedich-939	357	10	-	-	SYM
biomedich-939	357	11	982	982	NUM
biomedich-939	357	12	.	.	PUNCT
biomedich-939	358	1	ribeiro	ribeiro	PROPN
biomedich-939	358	2	,	,	PUNCT
biomedich-939	358	3	r.	r.	PROPN
biomedich-939	358	4	f.	f.	PROPN
biomedich-939	358	5	,	,	PUNCT
biomedich-939	358	6	marenich	marenich	PROPN
biomedich-939	358	7	,	,	PUNCT
biomedich-939	358	8	a.	a.	PROPN
biomedich-939	358	9	v.	v.	PROPN
biomedich-939	358	10	,	,	PUNCT
biomedich-939	358	11	cramer	cramer	PROPN
biomedich-939	358	12	,	,	PUNCT
biomedich-939	358	13	c.	c.	PROPN
biomedich-939	358	14	j.	j.	PROPN
biomedich-939	358	15	,	,	PUNCT
biomedich-939	358	16	&	&	CCONJ
biomedich-939	358	17	truhlar	truhlar	PROPN
biomedich-939	358	18	,	,	PUNCT
biomedich-939	358	19	d.	d.	PROPN
biomedich-939	358	20	g.	g.	PROPN
biomedich-939	358	21	(	(	PUNCT
biomedich-939	358	22	2011	2011	NUM
biomedich-939	358	23	)	)	PUNCT
biomedich-939	358	24	.	.	PUNCT
biomedich-939	359	1	the	the	DET
biomedich-939	359	2	solvation	solvation	NOUN
biomedich-939	359	3	,	,	PUNCT
biomedich-939	359	4	partitioning	partitioning	NOUN
biomedich-939	359	5	,	,	PUNCT
biomedich-939	359	6	hydrogen	hydrogen	NOUN
biomedich-939	359	7	bonding	bonding	NOUN
biomedich-939	359	8	,	,	PUNCT
biomedich-939	359	9	and	and	CCONJ
biomedich-939	359	10	dimerization	dimerization	NOUN
biomedich-939	359	11	of	of	ADP
biomedich-939	359	12	nucleotide	nucleotide	ADJ
biomedich-939	359	13	bases	basis	NOUN
biomedich-939	359	14	:	:	PUNCT
biomedich-939	359	15	a	a	DET
biomedich-939	359	16	multifaceted	multifaceted	ADJ
biomedich-939	359	17	challenge	challenge	NOUN
biomedich-939	359	18	for	for	ADP
biomedich-939	359	19	quantum	quantum	ADJ
biomedich-939	359	20	chemistry	chemistry	NOUN
biomedich-939	359	21	.	.	PUNCT
biomedich-939	360	1	physical	physical	ADJ
biomedich-939	360	2	chemistry	chemistry	NOUN
biomedich-939	360	3	chemical	chemical	PROPN
biomedich-939	360	4	physics	physics	PROPN
biomedich-939	360	5	,	,	PUNCT
biomedich-939	360	6	13	13	NUM
biomedich-939	360	7	,	,	PUNCT
biomedich-939	360	8	10908–10922	10908–10922	NUM
biomedich-939	360	9	.	.	PUNCT
biomedich-939	361	1	sagaama	sagaama	PROPN
biomedich-939	361	2	,	,	PUNCT
biomedich-939	361	3	a.	a.	NOUN
biomedich-939	361	4	,	,	PUNCT
biomedich-939	361	5	&	&	CCONJ
biomedich-939	361	6	issaoui	issaoui	NOUN
biomedich-939	361	7	,	,	PUNCT
biomedich-939	361	8	n.	n.	NOUN
biomedich-939	361	9	(	(	PUNCT
biomedich-939	361	10	2020	2020	NUM
biomedich-939	361	11	)	)	PUNCT
biomedich-939	361	12	.	.	PUNCT
biomedich-939	362	1	design	design	NOUN
biomedich-939	362	2	,	,	PUNCT
biomedich-939	362	3	molecular	molecular	ADJ
biomedich-939	362	4	docking	docking	NOUN
biomedich-939	362	5	analysis	analysis	NOUN
biomedich-939	362	6	of	of	ADP
biomedich-939	362	7	an	an	DET
biomedich-939	362	8	anti	anti	ADJ
biomedich-939	362	9	-	-	ADJ
biomedich-939	362	10	inflammatory	inflammatory	ADJ
biomedich-939	362	11	drug	drug	NOUN
biomedich-939	362	12	,	,	PUNCT
biomedich-939	362	13	computational	computational	ADJ
biomedich-939	362	14	analysis	analysis	NOUN
biomedich-939	362	15	and	and	CCONJ
biomedich-939	362	16	intermolecular	intermolecular	ADJ
biomedich-939	362	17	interactions	interaction	NOUN
biomedich-939	362	18	energy	energy	NOUN
biomedich-939	362	19	studies	study	NOUN
biomedich-939	362	20	of	of	ADP
biomedich-939	362	21	1benzothiophene-2	1benzothiophene-2	NUM
biomedich-939	362	22	-	-	PUNCT
biomedich-939	362	23	carboxylic	carboxylic	ADJ
biomedich-939	362	24	acid	acid	NOUN
biomedich-939	362	25	.	.	PUNCT
biomedich-939	363	1	computational	computational	ADJ
biomedich-939	363	2	biology	biology	NOUN
biomedich-939	363	3	and	and	CCONJ
biomedich-939	363	4	chemistry	chemistry	NOUN
biomedich-939	363	5	,	,	PUNCT
biomedich-939	363	6	88	88	NUM
biomedich-939	363	7	,	,	PUNCT
biomedich-939	363	8	107348	107348	NUM
biomedich-939	363	9	.	.	PUNCT
biomedich-939	364	1	sangster	sangster	PROPN
biomedich-939	364	2	,	,	PUNCT
biomedich-939	364	3	j.	j.	PROPN
biomedich-939	364	4	m.	m.	PROPN
biomedich-939	364	5	(	(	PUNCT
biomedich-939	364	6	1997	1997	NUM
biomedich-939	364	7	)	)	PUNCT
biomedich-939	364	8	.	.	PUNCT
biomedich-939	365	1	octanol	octanol	NOUN
biomedich-939	365	2	-	-	PUNCT
biomedich-939	365	3	water	water	NOUN
biomedich-939	365	4	partition	partition	NOUN
biomedich-939	365	5	coefficients	coefficient	NOUN
biomedich-939	365	6	:	:	PUNCT
biomedich-939	365	7	fundamentals	fundamental	NOUN
biomedich-939	365	8	and	and	CCONJ
biomedich-939	365	9	physical	physical	ADJ
biomedich-939	365	10	chemistry	chemistry	NOUN
biomedich-939	365	11	(	(	PUNCT
biomedich-939	365	12	vol	vol	NOUN
biomedich-939	365	13	.	.	NOUN
biomedich-939	365	14	1	1	NUM
biomedich-939	365	15	)	)	PUNCT
biomedich-939	365	16	.	.	PUNCT
biomedich-939	366	1	john	john	PROPN
biomedich-939	366	2	wiley	wiley	PROPN
biomedich-939	366	3	&	&	CCONJ
biomedich-939	366	4	sons	son	NOUN
biomedich-939	366	5	.	.	PUNCT
biomedich-939	367	1	856	856	NUM
biomedich-939	367	2	biology	biology	NOUN
biomedich-939	367	3	,	,	PUNCT
biomedich-939	367	4	medicine	medicine	NOUN
biomedich-939	367	5	,	,	PUNCT
biomedich-939	367	6	&	&	CCONJ
biomedich-939	367	7	natural	natural	ADJ
biomedich-939	367	8	product	product	NOUN
biomedich-939	367	9	chemistry	chemistry	NOUN
biomedich-939	367	10	14	14	NUM
biomedich-939	367	11	(	(	PUNCT
biomedich-939	367	12	2	2	NUM
biomedich-939	367	13	)	)	PUNCT
biomedich-939	367	14	,	,	PUNCT
biomedich-939	367	15	2025	2025	NUM
biomedich-939	367	16	:	:	PUNCT
biomedich-939	367	17	843	843	NUM
biomedich-939	367	18	-	-	SYM
biomedich-939	367	19	856	856	NUM
biomedich-939	367	20	sauvant	sauvant	NOUN
biomedich-939	367	21	,	,	PUNCT
biomedich-939	367	22	n.	n.	PROPN
biomedich-939	367	23	p.	p.	PROPN
biomedich-939	367	24	,	,	PUNCT
biomedich-939	367	25	pepin	pepin	PROPN
biomedich-939	367	26	,	,	PUNCT
biomedich-939	367	27	d.	d.	PROPN
biomedich-939	367	28	,	,	PUNCT
biomedich-939	367	29	&	&	CCONJ
biomedich-939	367	30	piccinni	piccinni	PROPN
biomedich-939	367	31	,	,	PUNCT
biomedich-939	367	32	e.	e.	PROPN
biomedich-939	367	33	(	(	PUNCT
biomedich-939	367	34	1999	1999	NUM
biomedich-939	367	35	)	)	PUNCT
biomedich-939	367	36	.	.	PUNCT
biomedich-939	368	1	tetrahymena	tetrahymena	NOUN
biomedich-939	368	2	pyriformis	pyriformis	PROPN
biomedich-939	368	3	:	:	PUNCT
biomedich-939	368	4	a	a	DET
biomedich-939	368	5	tool	tool	NOUN
biomedich-939	368	6	for	for	ADP
biomedich-939	368	7	toxicological	toxicological	ADJ
biomedich-939	368	8	studies	study	NOUN
biomedich-939	368	9	.	.	PUNCT
biomedich-939	369	1	a	a	DET
biomedich-939	369	2	review	review	NOUN
biomedich-939	369	3	.	.	PUNCT
biomedich-939	370	1	chemosphere	chemosphere	PROPN
biomedich-939	370	2	,	,	PUNCT
biomedich-939	370	3	38(7	38(7	NUM
biomedich-939	370	4	)	)	PUNCT
biomedich-939	370	5	,	,	PUNCT
biomedich-939	370	6	1631	1631	NUM
biomedich-939	370	7	-	-	SYM
biomedich-939	370	8	1669	1669	NUM
biomedich-939	370	9	.	.	PUNCT
biomedich-939	371	1	shaffer	shaffer	NOUN
biomedich-939	371	2	,	,	PUNCT
biomedich-939	371	3	p.	p.	PROPN
biomedich-939	371	4	l.	l.	PROPN
biomedich-939	371	5	,	,	PUNCT
biomedich-939	371	6	jivan	jivan	PROPN
biomedich-939	371	7	,	,	PUNCT
biomedich-939	371	8	a.	a.	NOUN
biomedich-939	371	9	,	,	PUNCT
biomedich-939	371	10	dollins	dollin	NOUN
biomedich-939	371	11	,	,	PUNCT
biomedich-939	371	12	d.	d.	PROPN
biomedich-939	371	13	e.	e.	PROPN
biomedich-939	371	14	,	,	PUNCT
biomedich-939	371	15	claessens	claessen	NOUN
biomedich-939	371	16	,	,	PUNCT
biomedich-939	371	17	f.	f.	PROPN
biomedich-939	371	18	,	,	PUNCT
biomedich-939	371	19	&	&	CCONJ
biomedich-939	371	20	gewirth	gewirth	PROPN
biomedich-939	371	21	,	,	PUNCT
biomedich-939	371	22	d.	d.	PROPN
biomedich-939	371	23	t.	t.	PROPN
biomedich-939	371	24	(	(	PUNCT
biomedich-939	371	25	2004	2004	NUM
biomedich-939	371	26	)	)	PUNCT
biomedich-939	371	27	.	.	PUNCT
biomedich-939	372	1	structural	structural	ADJ
biomedich-939	372	2	basis	basis	NOUN
biomedich-939	372	3	of	of	ADP
biomedich-939	372	4	androgen	androgen	NOUN
biomedich-939	372	5	receptor	receptor	NOUN
biomedich-939	372	6	binding	bind	VERB
biomedich-939	372	7	to	to	ADP
biomedich-939	372	8	selective	selective	ADJ
biomedich-939	372	9	androgen	androgen	NOUN
biomedich-939	372	10	response	response	NOUN
biomedich-939	372	11	elements	element	NOUN
biomedich-939	372	12	.	.	PUNCT
biomedich-939	373	1	proceedings	proceeding	NOUN
biomedich-939	373	2	of	of	ADP
biomedich-939	373	3	the	the	DET
biomedich-939	373	4	national	national	PROPN
biomedich-939	373	5	academy	academy	PROPN
biomedich-939	373	6	of	of	ADP
biomedich-939	373	7	sciences	sciences	PROPN
biomedich-939	373	8	,	,	PUNCT
biomedich-939	373	9	101(14	101(14	NUM
biomedich-939	373	10	)	)	PUNCT
biomedich-939	373	11	,	,	PUNCT
biomedich-939	373	12	4758	4758	NUM
biomedich-939	373	13	-	-	SYM
biomedich-939	373	14	4763	4763	NUM
biomedich-939	373	15	.	.	PUNCT
biomedich-939	374	1	sharma	sharma	PROPN
biomedich-939	374	2	,	,	PUNCT
biomedich-939	374	3	r.	r.	PROPN
biomedich-939	374	4	,	,	PUNCT
biomedich-939	374	5	kour	kour	NOUN
biomedich-939	374	6	,	,	PUNCT
biomedich-939	374	7	p.	p.	PROPN
biomedich-939	374	8	,	,	PUNCT
biomedich-939	374	9	&	&	CCONJ
biomedich-939	374	10	kumar	kumar	PROPN
biomedich-939	374	11	,	,	PUNCT
biomedich-939	374	12	a.	a.	NOUN
biomedich-939	374	13	(	(	PUNCT
biomedich-939	374	14	2018	2018	NUM
biomedich-939	374	15	)	)	PUNCT
biomedich-939	374	16	.	.	PUNCT
biomedich-939	375	1	a	a	DET
biomedich-939	375	2	review	review	NOUN
biomedich-939	375	3	on	on	ADP
biomedich-939	375	4	transitionmetal	transitionmetal	ADJ
biomedich-939	375	5	mediated	mediate	VERB
biomedich-939	375	6	synthesis	synthesis	NOUN
biomedich-939	375	7	of	of	ADP
biomedich-939	375	8	quinolines	quinoline	NOUN
biomedich-939	375	9	.	.	PUNCT
biomedich-939	376	1	journal	journal	PROPN
biomedich-939	376	2	of	of	ADP
biomedich-939	376	3	chemical	chemical	PROPN
biomedich-939	376	4	sciences	sciences	PROPN
biomedich-939	376	5	,	,	PUNCT
biomedich-939	376	6	130(6	130(6	NUM
biomedich-939	376	7	)	)	PUNCT
biomedich-939	376	8	,	,	PUNCT
biomedich-939	376	9	1	1	NUM
biomedich-939	376	10	-	-	SYM
biomedich-939	376	11	25	25	NUM
biomedich-939	376	12	.	.	PUNCT
biomedich-939	377	1	sheikhi	sheikhi	PROPN
biomedich-939	377	2	,	,	PUNCT
biomedich-939	377	3	m.	m.	NOUN
biomedich-939	377	4	,	,	PUNCT
biomedich-939	377	5	balali	balali	PROPN
biomedich-939	377	6	,	,	PUNCT
biomedich-939	377	7	e.	e.	PROPN
biomedich-939	377	8	,	,	PUNCT
biomedich-939	377	9	&	&	CCONJ
biomedich-939	377	10	lari	lari	PROPN
biomedich-939	377	11	,	,	PUNCT
biomedich-939	377	12	h.	h.	PROPN
biomedich-939	377	13	(	(	PUNCT
biomedich-939	377	14	2016	2016	NUM
biomedich-939	377	15	)	)	PUNCT
biomedich-939	377	16	.	.	PUNCT
biomedich-939	378	1	theoretical	theoretical	ADJ
biomedich-939	378	2	investigations	investigation	NOUN
biomedich-939	378	3	on	on	ADP
biomedich-939	378	4	molecular	molecular	ADJ
biomedich-939	378	5	structure	structure	NOUN
biomedich-939	378	6	,	,	PUNCT
biomedich-939	378	7	nbo	nbo	INTJ
biomedich-939	378	8	,	,	PUNCT
biomedich-939	378	9	homo	homo	NOUN
biomedich-939	378	10	-	-	PUNCT
biomedich-939	378	11	lumo	lumo	NOUN
biomedich-939	378	12	and	and	CCONJ
biomedich-939	378	13	mep	mep	PROPN
biomedich-939	378	14	analysis	analysis	NOUN
biomedich-939	378	15	of	of	ADP
biomedich-939	378	16	two	two	NUM
biomedich-939	378	17	crystal	crystal	NOUN
biomedich-939	378	18	structures	structure	NOUN
biomedich-939	378	19	of	of	ADP
biomedich-939	378	20	n-(2	n-(2	NOUN
biomedich-939	378	21	-	-	PUNCT
biomedich-939	378	22	benzoylphenyl)oxalyl	benzoylphenyl)oxalyl	PROPN
biomedich-939	378	23	:	:	PUNCT
biomedich-939	378	24	a	a	DET
biomedich-939	378	25	dft	dft	PROPN
biomedich-939	378	26	study	study	NOUN
biomedich-939	378	27	.	.	PUNCT
biomedich-939	379	1	journal	journal	PROPN
biomedich-939	379	2	of	of	ADP
biomedich-939	379	3	physical	physical	PROPN
biomedich-939	379	4	&	&	CCONJ
biomedich-939	379	5	theoretical	theoretical	ADJ
biomedich-939	379	6	chemistry	chemistry	NOUN
biomedich-939	379	7	,	,	PUNCT
biomedich-939	379	8	13(2	13(2	PROPN
biomedich-939	379	9	)	)	PUNCT
biomedich-939	379	10	,	,	PUNCT
biomedich-939	379	11	155	155	NUM
biomedich-939	379	12	-	-	SYM
biomedich-939	379	13	169	169	NUM
biomedich-939	379	14	.	.	PUNCT
biomedich-939	380	1	shinde	shinde	PROPN
biomedich-939	380	2	,	,	PUNCT
biomedich-939	380	3	r.	r.	PROPN
biomedich-939	380	4	s.	s.	PROPN
biomedich-939	380	5	(	(	PUNCT
biomedich-939	380	6	2021	2021	NUM
biomedich-939	380	7	)	)	PUNCT
biomedich-939	380	8	.	.	PUNCT
biomedich-939	381	1	synthesis	synthesis	NOUN
biomedich-939	381	2	,	,	PUNCT
biomedich-939	381	3	characterization	characterization	NOUN
biomedich-939	381	4	and	and	CCONJ
biomedich-939	381	5	theoretical	theoretical	ADJ
biomedich-939	381	6	insights	insight	NOUN
biomedich-939	381	7	into	into	ADP
biomedich-939	381	8	molecular	molecular	ADJ
biomedich-939	381	9	properties	property	NOUN
biomedich-939	381	10	of	of	ADP
biomedich-939	381	11	2-(4	2-(4	PROPN
biomedich-939	381	12	-	-	PUNCT
biomedich-939	381	13	fluorophenyl)-4hchromen-4	fluorophenyl)-4hchromen-4	PROPN
biomedich-939	381	14	-	-	PUNCT
biomedich-939	381	15	one	one	NUM
biomedich-939	381	16	.	.	PUNCT
biomedich-939	382	1	journal	journal	NOUN
biomedich-939	382	2	of	of	ADP
biomedich-939	382	3	advanced	advanced	ADJ
biomedich-939	382	4	chemical	chemical	NOUN
biomedich-939	382	5	sciences	science	NOUN
biomedich-939	382	6	,	,	PUNCT
biomedich-939	382	7	721724	721724	NUM
biomedich-939	382	8	.	.	PUNCT
biomedich-939	383	1	smalø	smalø	ADJ
biomedich-939	383	2	,	,	PUNCT
biomedich-939	383	3	h.	h.	PROPN
biomedich-939	383	4	s.	s.	PROPN
biomedich-939	383	5	,	,	PUNCT
biomedich-939	383	6	astrand	astrand	PROPN
biomedich-939	383	7	,	,	PUNCT
biomedich-939	383	8	p.	p.	PROPN
biomedich-939	383	9	o.	o.	PROPN
biomedich-939	383	10	,	,	PUNCT
biomedich-939	383	11	&	&	CCONJ
biomedich-939	383	12	ingebrigtsen	ingebrigtsen	PROPN
biomedich-939	383	13	,	,	PUNCT
biomedich-939	383	14	s.	s.	PROPN
biomedich-939	383	15	(	(	PUNCT
biomedich-939	383	16	2010	2010	NUM
biomedich-939	383	17	)	)	PUNCT
biomedich-939	383	18	.	.	PUNCT
biomedich-939	384	1	calculation	calculation	NOUN
biomedich-939	384	2	of	of	ADP
biomedich-939	384	3	ionization	ionization	NOUN
biomedich-939	384	4	potentials	potential	NOUN
biomedich-939	384	5	and	and	CCONJ
biomedich-939	384	6	electron	electron	NOUN
biomedich-939	384	7	affinities	affinity	NOUN
biomedich-939	384	8	for	for	ADP
biomedich-939	384	9	molecules	molecule	NOUN
biomedich-939	384	10	relevant	relevant	ADJ
biomedich-939	384	11	for	for	ADP
biomedich-939	384	12	streamer	streamer	NOUN
biomedich-939	384	13	initiation	initiation	NOUN
biomedich-939	384	14	and	and	CCONJ
biomedich-939	384	15	propagation	propagation	NOUN
biomedich-939	384	16	.	.	PUNCT
biomedich-939	385	1	ieee	ieee	NOUN
biomedich-939	385	2	transactions	transaction	NOUN
biomedich-939	385	3	on	on	ADP
biomedich-939	385	4	dielectrics	dielectric	NOUN
biomedich-939	385	5	and	and	CCONJ
biomedich-939	385	6	electrical	electrical	ADJ
biomedich-939	385	7	insulation	insulation	NOUN
biomedich-939	385	8	,	,	PUNCT
biomedich-939	385	9	17(3	17(3	NUM
biomedich-939	385	10	)	)	PUNCT
biomedich-939	385	11	,	,	PUNCT
biomedich-939	385	12	733	733	NUM
biomedich-939	385	13	-	-	SYM
biomedich-939	385	14	741	741	NUM
biomedich-939	385	15	.	.	PUNCT
biomedich-939	386	1	sumrra	sumrra	PROPN
biomedich-939	386	2	,	,	PUNCT
biomedich-939	386	3	s.	s.	PROPN
biomedich-939	386	4	h.	h.	PROPN
biomedich-939	386	5	,	,	PUNCT
biomedich-939	386	6	zafar	zafar	PROPN
biomedich-939	386	7	,	,	PUNCT
biomedich-939	386	8	w.	w.	PROPN
biomedich-939	386	9	,	,	PUNCT
biomedich-939	386	10	asghar	asghar	PROPN
biomedich-939	386	11	,	,	PUNCT
biomedich-939	386	12	m.	m.	PROPN
biomedich-939	386	13	l.	l.	PROPN
biomedich-939	386	14	,	,	PUNCT
biomedich-939	386	15	mushtaq	mushtaq	PROPN
biomedich-939	386	16	,	,	PUNCT
biomedich-939	386	17	f.	f.	PROPN
biomedich-939	386	18	,	,	PUNCT
biomedich-939	386	19	raza	raza	PROPN
biomedich-939	386	20	,	,	PUNCT
biomedich-939	386	21	m.	m.	NOUN
biomedich-939	386	22	a.	a.	PROPN
biomedich-939	386	23	,	,	PUNCT
biomedich-939	386	24	nazar	nazar	PROPN
biomedich-939	386	25	,	,	PUNCT
biomedich-939	386	26	m.	m.	NOUN
biomedich-939	386	27	f.	f.	PROPN
biomedich-939	386	28	,	,	PUNCT
biomedich-939	386	29	...	...	PUNCT
biomedich-939	386	30	&	&	CCONJ
biomedich-939	386	31	mumtaz	mumtaz	PROPN
biomedich-939	386	32	,	,	PUNCT
biomedich-939	386	33	s.	s.	PROPN
biomedich-939	386	34	(	(	PUNCT
biomedich-939	386	35	2021	2021	NUM
biomedich-939	386	36	)	)	PUNCT
biomedich-939	386	37	.	.	PUNCT
biomedich-939	387	1	computational	computational	ADJ
biomedich-939	387	2	investigation	investigation	NOUN
biomedich-939	387	3	of	of	ADP
biomedich-939	387	4	molecular	molecular	ADJ
biomedich-939	387	5	structures	structure	NOUN
biomedich-939	387	6	,	,	PUNCT
biomedich-939	387	7	spectroscopic	spectroscopic	ADJ
biomedich-939	387	8	properties	property	NOUN
biomedich-939	387	9	,	,	PUNCT
biomedich-939	387	10	cholinesterase	cholinesterase	NOUN
biomedich-939	387	11	inhibition	inhibition	NOUN
biomedich-939	387	12	and	and	CCONJ
biomedich-939	387	13	antibacterial	antibacterial	ADJ
biomedich-939	387	14	activities	activity	NOUN
biomedich-939	387	15	of	of	ADP
biomedich-939	387	16	triazole	triazole	ADJ
biomedich-939	387	17	schiff	schiff	NOUN
biomedich-939	387	18	bases	basis	NOUN
biomedich-939	387	19	endowed	endow	VERB
biomedich-939	387	20	metal	metal	NOUN
biomedich-939	387	21	chelates	chelate	NOUN
biomedich-939	387	22	.	.	PUNCT
biomedich-939	388	1	journal	journal	NOUN
biomedich-939	388	2	of	of	ADP
biomedich-939	388	3	molecular	molecular	ADJ
biomedich-939	388	4	structure	structure	NOUN
biomedich-939	388	5	,	,	PUNCT
biomedich-939	388	6	1238	1238	NUM
biomedich-939	388	7	,	,	PUNCT
biomedich-939	388	8	130382	130382	NUM
biomedich-939	388	9	.	.	PUNCT
biomedich-939	389	1	suzuki	suzuki	PROPN
biomedich-939	389	2	,	,	PUNCT
biomedich-939	389	3	t.	t.	PROPN
biomedich-939	389	4	,	,	PUNCT
biomedich-939	389	5	fukazawa	fukazawa	PROPN
biomedich-939	389	6	,	,	PUNCT
biomedich-939	389	7	n.	n.	NOUN
biomedich-939	389	8	,	,	PUNCT
biomedich-939	389	9	san	san	PROPN
biomedich-939	389	10	-	-	PUNCT
biomedich-939	389	11	nohe	nohe	NOUN
biomedich-939	389	12	,	,	PUNCT
biomedich-939	389	13	k.	k.	PROPN
biomedich-939	389	14	,	,	PUNCT
biomedich-939	389	15	sato	sato	PROPN
biomedich-939	389	16	,	,	PUNCT
biomedich-939	389	17	w.	w.	PROPN
biomedich-939	389	18	,	,	PUNCT
biomedich-939	389	19	yano	yano	PROPN
biomedich-939	389	20	,	,	PUNCT
biomedich-939	389	21	o.	o.	PROPN
biomedich-939	389	22	,	,	PUNCT
biomedich-939	389	23	&	&	CCONJ
biomedich-939	389	24	tsuruo	tsuruo	ADJ
biomedich-939	389	25	,	,	PUNCT
biomedich-939	389	26	t.	t.	PROPN
biomedich-939	389	27	(	(	PUNCT
biomedich-939	389	28	1997	1997	NUM
biomedich-939	389	29	)	)	PUNCT
biomedich-939	389	30	.	.	PUNCT
biomedich-939	390	1	structure−	structure−	ADJ
biomedich-939	390	2	activity	activity	NOUN
biomedich-939	390	3	relationship	relationship	NOUN
biomedich-939	390	4	of	of	ADP
biomedich-939	390	5	newly	newly	ADV
biomedich-939	390	6	synthesized	synthesize	VERB
biomedich-939	390	7	quinoline	quinoline	NOUN
biomedich-939	390	8	derivatives	derivative	NOUN
biomedich-939	390	9	for	for	ADP
biomedich-939	390	10	reversal	reversal	NOUN
biomedich-939	390	11	of	of	ADP
biomedich-939	390	12	multidrug	multidrug	NOUN
biomedich-939	390	13	resistance	resistance	NOUN
biomedich-939	390	14	in	in	ADP
biomedich-939	390	15	cancer	cancer	NOUN
biomedich-939	390	16	.	.	PUNCT
biomedich-939	391	1	journal	journal	PROPN
biomedich-939	391	2	of	of	ADP
biomedich-939	391	3	medicinal	medicinal	ADJ
biomedich-939	391	4	chemistry	chemistry	NOUN
biomedich-939	391	5	,	,	PUNCT
biomedich-939	391	6	40(13	40(13	NOUN
biomedich-939	391	7	)	)	PUNCT
biomedich-939	391	8	,	,	PUNCT
biomedich-939	391	9	2047	2047	NUM
biomedich-939	391	10	-	-	SYM
biomedich-939	391	11	2052	2052	NUM
biomedich-939	391	12	.	.	PUNCT
biomedich-939	392	1	tandon	tandon	PROPN
biomedich-939	392	2	,	,	PUNCT
biomedich-939	392	3	h.	h.	PROPN
biomedich-939	392	4	,	,	PUNCT
biomedich-939	392	5	chakraborty	chakraborty	PROPN
biomedich-939	392	6	,	,	PUNCT
biomedich-939	392	7	t.	t.	PROPN
biomedich-939	392	8	,	,	PUNCT
biomedich-939	392	9	&	&	CCONJ
biomedich-939	392	10	suhag	suhag	PROPN
biomedich-939	392	11	,	,	PUNCT
biomedich-939	392	12	v.	v.	PROPN
biomedich-939	392	13	(	(	PUNCT
biomedich-939	392	14	2020	2020	NUM
biomedich-939	392	15	)	)	PUNCT
biomedich-939	392	16	.	.	PUNCT
biomedich-939	393	1	a	a	DET
biomedich-939	393	2	fundamental	fundamental	ADJ
biomedich-939	393	3	approach	approach	NOUN
biomedich-939	393	4	to	to	PART
biomedich-939	393	5	compute	compute	VERB
biomedich-939	393	6	atomic	atomic	ADJ
biomedich-939	393	7	electrophilicity	electrophilicity	NOUN
biomedich-939	393	8	index	index	NOUN
biomedich-939	393	9	.	.	PUNCT
biomedich-939	394	1	journal	journal	PROPN
biomedich-939	394	2	of	of	ADP
biomedich-939	394	3	mathematical	mathematical	ADJ
biomedich-939	394	4	chemistry	chemistry	NOUN
biomedich-939	394	5	,	,	PUNCT
biomedich-939	394	6	58(9	58(9	NOUN
biomedich-939	394	7	)	)	PUNCT
biomedich-939	394	8	,	,	PUNCT
biomedich-939	394	9	2188	2188	NUM
biomedich-939	394	10	-	-	SYM
biomedich-939	394	11	2196	2196	NUM
biomedich-939	394	12	.	.	PUNCT
biomedich-939	395	1	trainor	trainor	PROPN
biomedich-939	395	2	,	,	PUNCT
biomedich-939	395	3	g.	g.	PROPN
biomedich-939	395	4	l.	l.	PROPN
biomedich-939	395	5	(	(	PUNCT
biomedich-939	395	6	2007	2007	NUM
biomedich-939	395	7	)	)	PUNCT
biomedich-939	395	8	.	.	PUNCT
biomedich-939	396	1	the	the	DET
biomedich-939	396	2	importance	importance	NOUN
biomedich-939	396	3	of	of	ADP
biomedich-939	396	4	plasma	plasma	NOUN
biomedich-939	396	5	protein	protein	NOUN
biomedich-939	396	6	binding	bind	VERB
biomedich-939	396	7	in	in	ADP
biomedich-939	396	8	drug	drug	NOUN
biomedich-939	396	9	discovery	discovery	NOUN
biomedich-939	396	10	.	.	PUNCT
biomedich-939	397	1	expert	expert	ADJ
biomedich-939	397	2	opinion	opinion	NOUN
biomedich-939	397	3	on	on	ADP
biomedich-939	397	4	drug	drug	NOUN
biomedich-939	397	5	discovery	discovery	NOUN
biomedich-939	397	6	,	,	PUNCT
biomedich-939	397	7	2(1	2(1	NUM
biomedich-939	397	8	)	)	PUNCT
biomedich-939	397	9	,	,	PUNCT
biomedich-939	397	10	5164	5164	NUM
biomedich-939	397	11	.	.	PUNCT
biomedich-939	398	1	van	van	PROPN
biomedich-939	398	2	der	der	PROPN
biomedich-939	398	3	merwe	merwe	PROPN
biomedich-939	398	4	,	,	PUNCT
biomedich-939	398	5	d.	d.	PROPN
biomedich-939	398	6	(	(	PUNCT
biomedich-939	398	7	2018	2018	NUM
biomedich-939	398	8	)	)	PUNCT
biomedich-939	398	9	.	.	PUNCT
biomedich-939	399	1	respiratory	respiratory	ADJ
biomedich-939	399	2	toxicity	toxicity	NOUN
biomedich-939	399	3	.	.	PUNCT
biomedich-939	400	1	in	in	ADP
biomedich-939	400	2	veterinary	veterinary	ADJ
biomedich-939	400	3	toxicology	toxicology	NOUN
biomedich-939	400	4	(	(	PUNCT
biomedich-939	400	5	pp	pp	ADJ
biomedich-939	400	6	.	.	PUNCT
biomedich-939	401	1	215	215	NUM
biomedich-939	401	2	-	-	SYM
biomedich-939	401	3	226	226	NUM
biomedich-939	401	4	)	)	PUNCT
biomedich-939	401	5	.	.	PUNCT
biomedich-939	402	1	academic	academic	ADJ
biomedich-939	402	2	press	press	NOUN
biomedich-939	402	3	.	.	PUNCT
biomedich-939	403	1	veber	veber	PROPN
biomedich-939	403	2	,	,	PUNCT
biomedich-939	403	3	d.	d.	PROPN
biomedich-939	403	4	f.	f.	PROPN
biomedich-939	403	5	,	,	PUNCT
biomedich-939	403	6	johnson	johnson	PROPN
biomedich-939	403	7	,	,	PUNCT
biomedich-939	403	8	s.	s.	PROPN
biomedich-939	403	9	r.	r.	PROPN
biomedich-939	403	10	,	,	PUNCT
biomedich-939	403	11	cheng	cheng	PROPN
biomedich-939	403	12	,	,	PUNCT
biomedich-939	403	13	h.	h.	PROPN
biomedich-939	403	14	y.	y.	PROPN
biomedich-939	403	15	,	,	PUNCT
biomedich-939	403	16	smith	smith	PROPN
biomedich-939	403	17	,	,	PUNCT
biomedich-939	403	18	b.	b.	PROPN
biomedich-939	403	19	r.	r.	PROPN
biomedich-939	403	20	,	,	PUNCT
biomedich-939	403	21	ward	ward	PROPN
biomedich-939	403	22	,	,	PUNCT
biomedich-939	403	23	k.	k.	PROPN
biomedich-939	403	24	w.	w.	PROPN
biomedich-939	403	25	,	,	PUNCT
biomedich-939	403	26	&	&	CCONJ
biomedich-939	403	27	kopple	kopple	PROPN
biomedich-939	403	28	,	,	PUNCT
biomedich-939	403	29	k.	k.	PROPN
biomedich-939	403	30	d.	d.	PROPN
biomedich-939	403	31	(	(	PUNCT
biomedich-939	403	32	2002	2002	NUM
biomedich-939	403	33	)	)	PUNCT
biomedich-939	403	34	.	.	PUNCT
biomedich-939	404	1	molecular	molecular	ADJ
biomedich-939	404	2	properties	property	NOUN
biomedich-939	404	3	that	that	PRON
biomedich-939	404	4	influence	influence	VERB
biomedich-939	404	5	the	the	DET
biomedich-939	404	6	oral	oral	ADJ
biomedich-939	404	7	bioavailability	bioavailability	NOUN
biomedich-939	404	8	of	of	ADP
biomedich-939	404	9	drug	drug	NOUN
biomedich-939	404	10	candidates	candidate	NOUN
biomedich-939	404	11	.	.	PUNCT
biomedich-939	405	1	journal	journal	NOUN
biomedich-939	405	2	of	of	ADP
biomedich-939	405	3	medicinal	medicinal	ADJ
biomedich-939	405	4	chemistry	chemistry	NOUN
biomedich-939	405	5	,	,	PUNCT
biomedich-939	405	6	45(12	45(12	NUM
biomedich-939	405	7	)	)	PUNCT
biomedich-939	405	8	,	,	PUNCT
biomedich-939	405	9	2615–2623	2615–2623	NUM
biomedich-939	405	10	.	.	PUNCT
biomedich-939	406	1	vlahovi´c	vlahovi´c	PROPN
biomedich-939	406	2	,	,	PUNCT
biomedich-939	406	3	f.	f.	PROPN
biomedich-939	406	4	,	,	PUNCT
biomedich-939	406	5	ivahovi´c	ivahovi´c	PROPN
biomedich-939	406	6	,	,	PUNCT
biomedich-939	406	7	s.	s.	PROPN
biomedich-939	406	8	,	,	PUNCT
biomedich-939	406	9	zlatar	zlatar	NOUN
biomedich-939	406	10	,	,	PUNCT
biomedich-939	406	11	m.	m.	NOUN
biomedich-939	406	12	,	,	PUNCT
biomedich-939	406	13	&	&	CCONJ
biomedich-939	406	14	gruden	gruden	PROPN
biomedich-939	406	15	,	,	PUNCT
biomedich-939	406	16	m.	m.	NOUN
biomedich-939	406	17	(	(	PUNCT
biomedich-939	406	18	2017	2017	NUM
biomedich-939	406	19	)	)	PUNCT
biomedich-939	406	20	.	.	PUNCT
biomedich-939	407	1	density	density	NOUN
biomedich-939	407	2	functional	functional	ADJ
biomedich-939	407	3	theory	theory	NOUN
biomedich-939	407	4	calculation	calculation	NOUN
biomedich-939	407	5	of	of	ADP
biomedich-939	407	6	lipophilicity	lipophilicity	NOUN
biomedich-939	407	7	for	for	ADP
biomedich-939	407	8	organophosphate	organophosphate	NOUN
biomedich-939	407	9	type	type	NOUN
biomedich-939	407	10	pesticides	pesticide	NOUN
biomedich-939	407	11	.	.	PUNCT
biomedich-939	408	1	journal	journal	NOUN
biomedich-939	408	2	of	of	ADP
biomedich-939	408	3	the	the	DET
biomedich-939	408	4	serbian	serbian	ADJ
biomedich-939	408	5	chemical	chemical	NOUN
biomedich-939	408	6	society	society	NOUN
biomedich-939	408	7	,	,	PUNCT
biomedich-939	408	8	82	82	NUM
biomedich-939	408	9	,	,	PUNCT
biomedich-939	408	10	1369–1378	1369–1378	NUM
biomedich-939	408	11	.	.	PUNCT
biomedich-939	409	1	voiculescu	voiculescu	PROPN
biomedich-939	409	2	,	,	PUNCT
biomedich-939	409	3	d.	d.	PROPN
biomedich-939	409	4	i.	i.	PROPN
biomedich-939	409	5	,	,	PUNCT
biomedich-939	409	6	roman	roman	PROPN
biomedich-939	409	7	,	,	PUNCT
biomedich-939	409	8	d.	d.	PROPN
biomedich-939	409	9	l.	l.	PROPN
biomedich-939	409	10	,	,	PUNCT
biomedich-939	409	11	ostafe	ostafe	NOUN
biomedich-939	409	12	,	,	PUNCT
biomedich-939	409	13	v.	v.	ADJ
biomedich-939	409	14	,	,	PUNCT
biomedich-939	409	15	&	&	CCONJ
biomedich-939	409	16	isvoran	isvoran	NOUN
biomedich-939	409	17	,	,	PUNCT
biomedich-939	409	18	a.	a.	NOUN
biomedich-939	409	19	(	(	PUNCT
biomedich-939	409	20	2022	2022	NUM
biomedich-939	409	21	)	)	PUNCT
biomedich-939	409	22	.	.	PUNCT
biomedich-939	410	1	a	a	DET
biomedich-939	410	2	cheminformatics	cheminformatics	PROPN
biomedich-939	410	3	study	study	NOUN
biomedich-939	410	4	regarding	regard	VERB
biomedich-939	410	5	the	the	DET
biomedich-939	410	6	human	human	ADJ
biomedich-939	410	7	health	health	NOUN
biomedich-939	410	8	risks	risk	NOUN
biomedich-939	410	9	assessment	assessment	NOUN
biomedich-939	410	10	of	of	ADP
biomedich-939	410	11	the	the	DET
biomedich-939	410	12	stereoisomers	stereoisomer	NOUN
biomedich-939	410	13	of	of	ADP
biomedich-939	410	14	difenoconazole	difenoconazole	NOUN
biomedich-939	410	15	.	.	PUNCT
biomedich-939	411	1	molecules	molecule	NOUN
biomedich-939	411	2	,	,	PUNCT
biomedich-939	411	3	27(15	27(15	NUM
biomedich-939	411	4	)	)	PUNCT
biomedich-939	411	5	,	,	PUNCT
biomedich-939	411	6	4682	4682	NUM
biomedich-939	411	7	.	.	PUNCT
biomedich-939	412	1	wang	wang	PROPN
biomedich-939	412	2	,	,	PUNCT
biomedich-939	412	3	b.	b.	PROPN
biomedich-939	412	4	,	,	PUNCT
biomedich-939	412	5	&	&	CCONJ
biomedich-939	412	6	truhlar	truhlar	PROPN
biomedich-939	412	7	,	,	PUNCT
biomedich-939	412	8	d.	d.	PROPN
biomedich-939	412	9	g.	g.	PROPN
biomedich-939	412	10	(	(	PUNCT
biomedich-939	412	11	2014	2014	NUM
biomedich-939	412	12	)	)	PUNCT
biomedich-939	412	13	.	.	PUNCT
biomedich-939	412	14	screened	screen	VERB
biomedich-939	412	15	electrostatic	electrostatic	ADJ
biomedich-939	412	16	interactions	interaction	NOUN
biomedich-939	412	17	in	in	ADP
biomedich-939	412	18	molecular	molecular	ADJ
biomedich-939	412	19	mechanics	mechanic	NOUN
biomedich-939	412	20	.	.	PUNCT
biomedich-939	413	1	journal	journal	PROPN
biomedich-939	413	2	of	of	ADP
biomedich-939	413	3	chemical	chemical	PROPN
biomedich-939	413	4	theory	theory	NOUN
biomedich-939	413	5	and	and	CCONJ
biomedich-939	413	6	computation	computation	NOUN
biomedich-939	413	7	,	,	PUNCT
biomedich-939	413	8	10(10	10(10	NUM
biomedich-939	413	9	)	)	PUNCT
biomedich-939	413	10	,	,	PUNCT
biomedich-939	413	11	4480	4480	NUM
biomedich-939	413	12	-	-	SYM
biomedich-939	413	13	4487	4487	NUM
biomedich-939	413	14	.	.	PUNCT
biomedich-939	414	1	yoshida	yoshida	PROPN
biomedich-939	414	2	,	,	PUNCT
biomedich-939	414	3	f.	f.	PROPN
biomedich-939	414	4	,	,	PUNCT
biomedich-939	414	5	&	&	CCONJ
biomedich-939	414	6	topliss	topliss	PROPN
biomedich-939	414	7	,	,	PUNCT
biomedich-939	414	8	j.	j.	PROPN
biomedich-939	414	9	g.	g.	PROPN
biomedich-939	414	10	(	(	PUNCT
biomedich-939	414	11	2000	2000	NUM
biomedich-939	414	12	)	)	PUNCT
biomedich-939	414	13	.	.	PUNCT
biomedich-939	415	1	qsar	qsar	PROPN
biomedich-939	415	2	model	model	NOUN
biomedich-939	415	3	for	for	ADP
biomedich-939	415	4	drug	drug	NOUN
biomedich-939	415	5	human	human	ADJ
biomedich-939	415	6	oral	oral	ADJ
biomedich-939	415	7	bioavailability	bioavailability	NOUN
biomedich-939	415	8	.	.	PUNCT
biomedich-939	416	1	journal	journal	PROPN
biomedich-939	416	2	of	of	ADP
biomedich-939	416	3	medicinal	medicinal	ADJ
biomedich-939	416	4	chemistry	chemistry	NOUN
biomedich-939	416	5	,	,	PUNCT
biomedich-939	416	6	43(13	43(13	PROPN
biomedich-939	416	7	)	)	PUNCT
biomedich-939	416	8	,	,	PUNCT
biomedich-939	416	9	2575	2575	NUM
biomedich-939	416	10	-	-	SYM
biomedich-939	416	11	2585	2585	NUM
biomedich-939	416	12	.	.	PUNCT
biomedich-939	417	1	zhang	zhang	PROPN
biomedich-939	417	2	,	,	PUNCT
biomedich-939	417	3	j.	j.	PROPN
biomedich-939	417	4	,	,	PUNCT
biomedich-939	417	5	&	&	CCONJ
biomedich-939	417	6	lazar	lazar	PROPN
biomedich-939	417	7	,	,	PUNCT
biomedich-939	417	8	m.	m.	NOUN
biomedich-939	417	9	a.	a.	NOUN
biomedich-939	417	10	(	(	PUNCT
biomedich-939	417	11	2000	2000	NUM
biomedich-939	417	12	)	)	PUNCT
biomedich-939	417	13	.	.	PUNCT
biomedich-939	418	1	the	the	DET
biomedich-939	418	2	mechanism	mechanism	NOUN
biomedich-939	418	3	of	of	ADP
biomedich-939	418	4	action	action	NOUN
biomedich-939	418	5	of	of	ADP
biomedich-939	418	6	thyroid	thyroid	NOUN
biomedich-939	418	7	hormones	hormone	NOUN
biomedich-939	418	8	.	.	PUNCT
biomedich-939	419	1	annual	annual	ADJ
biomedich-939	419	2	review	review	NOUN
biomedich-939	419	3	of	of	ADP
biomedich-939	419	4	physiology	physiology	NOUN
biomedich-939	419	5	,	,	PUNCT
biomedich-939	419	6	62	62	NUM
biomedich-939	419	7	.	.	PUNCT
biomedich-939	420	1	zheng	zheng	PROPN
biomedich-939	420	2	,	,	PUNCT
biomedich-939	420	3	h.	h.	PROPN
biomedich-939	420	4	,	,	PUNCT
biomedich-939	420	5	jie	jie	PROPN
biomedich-939	420	6	,	,	PUNCT
biomedich-939	420	7	j.	j.	PROPN
biomedich-939	420	8	,	,	PUNCT
biomedich-939	420	9	&	&	CCONJ
biomedich-939	420	10	zheng	zheng	PROPN
biomedich-939	420	11	,	,	PUNCT
biomedich-939	420	12	y.	y.	PROPN
biomedich-939	420	13	(	(	PUNCT
biomedich-939	420	14	2013	2013	NUM
biomedich-939	420	15	)	)	PUNCT
biomedich-939	420	16	.	.	PUNCT
biomedich-939	421	1	multi	multi	ADJ
biomedich-939	421	2	-	-	ADJ
biomedich-939	421	3	swarm	swarm	ADJ
biomedich-939	421	4	chaotic	chaotic	ADJ
biomedich-939	421	5	particle	particle	NOUN
biomedich-939	421	6	swarm	swarm	NOUN
biomedich-939	421	7	optimization	optimization	NOUN
biomedich-939	421	8	for	for	ADP
biomedich-939	421	9	protein	protein	NOUN
biomedich-939	421	10	folding	folding	NOUN
biomedich-939	421	11	.	.	PUNCT
biomedich-939	422	1	journal	journal	NOUN
biomedich-939	422	2	of	of	ADP
biomedich-939	422	3	bionanoscience	bionanoscience	NOUN
biomedich-939	422	4	,	,	PUNCT
biomedich-939	422	5	7	7	NUM
biomedich-939	422	6	,	,	PUNCT
biomedich-939	422	7	643–648	643–648	NUM
biomedich-939	422	8	.	.	PUNCT