id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-031416-ytbs95wi	Sabzpoushan, S. H.	A System Biology-Based Approach for Designing Combination Therapy in Cancer Precision Medicine	2020-08-26		.txt	text/plain	9622	370	45	The recognition that cancer cells need their microenvironment to efficiently display their phenotype has opened the door to hypothesize and implement new therapeutic strategies. The trastuzumab moiety of this ADC binds to HER2 on tumor cell surfaces; upon internalization, the DM1 moiety is released and binds to tubulin, thereby disrupting microtubule assembly/disassembly dynamics and inhibiting cell division and the proliferation of cancer cells that overexpress HER2.	cache/cord-031416-ytbs95wi.txt	txt/cord-031416-ytbs95wi.txt
