id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
brj-24797	Zhang, Aling; Ji, Jialiu; Wu, Jiani; Liu, Jin; Wu, Shuangjian	Suppression of NF κB p65 and STAT3 by Melicope pteleifolia Extract Mitigates Ovalbumin Driven Allergic Rhinitis in Mice	2025	17	.pdf	application/pdf	6862	334	46	9296 Suppression of NF-κB-p65 and STAT3 by Melicope pteleifolia Extract Mitigates Ovalbumin-Driven Allergic Rhinitis in Mice Aling Zhang,a,# Jialiu Ji,b,# Jiani Wu,c Jin Liu,c and Shuangjian Wu ,c,* Allergic rhinitis (AR) is an IgE-mediated inflammatory disorder of the nasal mucosa, characterized by epithelial barrier disruption, immune cell infiltration, and cytokine imbalance. DOI: 10.15376/biores.20.4.9296-9311 Keywords: Ovalbumin; Cytokine; Eosinophils; NF-κB-p65; IκBα Contact information: a: Department of Otolaryngology, The Second Affiliated Hospital of Xi 'an Jiaotong University, Xi'an Shaanxi, 710004, China; b: Department of Otolaryngology, Jiangwan Hospital Hongkou District Shanghai, Shanghai, 200434, China; c: Department of Otolaryngology, Hangzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Zhejiang Hangzhou, 310007, China; # co-first authors, contributed equally to this work; * Corresponding author: wushuanger2980@outlook.com INTRODUCTION Allergic rhinitis (AR) is an immunoglobulin E–mediated inflammation of the nasal mucosa triggered by innocuous airborne allergens—pollens, dust mites, animal dander, molds and cockroach proteins—leading to sneezing, rhinorrhea, congestion, and itching, often accompanied by ocular symptoms (Incorvaia et al. 2018).	cache/brj-24797.pdf	txt/brj-24797.txt