id	sid	tid	token	lemma	pos
brj-23874	1	1	peer	peer	NOUN
brj-23874	1	2	-	-	PUNCT
brj-23874	1	3	review	review	NOUN
brj-23874	1	4	article	article	NOUN
brj-23874	1	5	peer	peer	NOUN
brj-23874	1	6	-	-	PUNCT
brj-23874	1	7	reviewed	review	VERB
brj-23874	1	8	article	article	NOUN
brj-23874	1	9	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	1	10	zhu	zhu	PROPN
brj-23874	1	11	et	et	PROPN
brj-23874	1	12	al	al	PROPN
brj-23874	1	13	.	.	PROPN
brj-23874	2	1	(	(	PUNCT
brj-23874	2	2	2026	2026	NUM
brj-23874	2	3	)	)	PUNCT
brj-23874	2	4	.	.	PUNCT
brj-23874	3	1	“	"	PUNCT
brj-23874	3	2	pain	pain	NOUN
brj-23874	3	3	control	control	NOUN
brj-23874	3	4	with	with	ADP
brj-23874	3	5	seed	seed	NOUN
brj-23874	3	6	extract	extract	NOUN
brj-23874	3	7	,	,	PUNCT
brj-23874	3	8	”	"	PUNCT
brj-23874	3	9	bioresources	bioresource	NOUN
brj-23874	3	10	21(1	21(1	NUM
brj-23874	3	11	)	)	PUNCT
brj-23874	3	12	,	,	PUNCT
brj-23874	3	13	116	116	NUM
brj-23874	3	14	-	-	SYM
brj-23874	3	15	127	127	NUM
brj-23874	3	16	.	.	PUNCT
brj-23874	4	1	115	115	NUM
brj-23874	4	2	preparation	preparation	NOUN
brj-23874	4	3	of	of	ADP
brj-23874	4	4	citrullus	citrullus	PROPN
brj-23874	4	5	colocynthis	colocynthis	NOUN
brj-23874	4	6	seed	seed	NOUN
brj-23874	4	7	extract	extract	NOUN
brj-23874	4	8	and	and	CCONJ
brj-23874	4	9	assessment	assessment	NOUN
brj-23874	4	10	of	of	ADP
brj-23874	4	11	cyto	cyto	NOUN
brj-23874	4	12	-	-	PUNCT
brj-23874	4	13	toxicity	toxicity	NOUN
brj-23874	4	14	,	,	PUNCT
brj-23874	4	15	anti	anti	ADJ
brj-23874	4	16	-	-	ADJ
brj-23874	4	17	microbial	microbial	ADJ
brj-23874	4	18	,	,	PUNCT
brj-23874	4	19	anti	anti	ADJ
brj-23874	4	20	-	-	ADJ
brj-23874	4	21	inflammatory	inflammatory	ADJ
brj-23874	4	22	,	,	PUNCT
brj-23874	4	23	and	and	CCONJ
brj-23874	4	24	analgesic	analgesic	ADJ
brj-23874	4	25	activities	activity	NOUN
brj-23874	4	26	zihan	zihan	PROPN
brj-23874	4	27	zhu	zhu	PROPN
brj-23874	4	28	,	,	PUNCT
brj-23874	4	29	a	a	DET
brj-23874	4	30	jie	jie	PROPN
brj-23874	4	31	zhang	zhang	PROPN
brj-23874	4	32	,	,	PUNCT
brj-23874	4	33	b	b	PROPN
brj-23874	4	34	,	,	PUNCT
brj-23874	4	35	*	*	PUNCT
brj-23874	4	36	and	and	CCONJ
brj-23874	4	37	huan	huan	PROPN
brj-23874	4	38	meng	meng	PROPN
brj-23874	4	39	c	c	PROPN
brj-23874	4	40	,	,	PUNCT
brj-23874	4	41	*	*	PUNCT
brj-23874	4	42	*	*	PUNCT
brj-23874	4	43	corresponding	correspond	VERB
brj-23874	4	44	authors	author	NOUN
brj-23874	4	45	:	:	PUNCT
brj-23874	4	46	15526771260@163.com	15526771260@163.com	NUM
brj-23874	4	47	;	;	PUNCT
brj-23874	4	48	jiezhangj99@hotmail.com	jiezhangj99@hotmail.com	PROPN
brj-23874	4	49	doi	doi	NOUN
brj-23874	4	50	:	:	PUNCT
brj-23874	4	51	10.15376	10.15376	NUM
brj-23874	4	52	/	/	SYM
brj-23874	4	53	biores.21.1.116	biores.21.1.116	ADP
brj-23874	4	54	-	-	PUNCT
brj-23874	4	55	127	127	NUM
brj-23874	4	56	graphical	graphical	ADJ
brj-23874	4	57	abstract	abstract	ADJ
brj-23874	4	58	peer	peer	NOUN
brj-23874	4	59	-	-	PUNCT
brj-23874	4	60	reviewed	review	VERB
brj-23874	4	61	article	article	NOUN
brj-23874	4	62	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	4	63	zhu	zhu	PROPN
brj-23874	4	64	et	et	PROPN
brj-23874	4	65	al	al	PROPN
brj-23874	4	66	.	.	PROPN
brj-23874	5	1	(	(	PUNCT
brj-23874	5	2	2026	2026	NUM
brj-23874	5	3	)	)	PUNCT
brj-23874	5	4	.	.	PUNCT
brj-23874	6	1	“	"	PUNCT
brj-23874	6	2	pain	pain	NOUN
brj-23874	6	3	control	control	NOUN
brj-23874	6	4	with	with	ADP
brj-23874	6	5	seed	seed	NOUN
brj-23874	6	6	extract	extract	NOUN
brj-23874	6	7	,	,	PUNCT
brj-23874	6	8	”	"	PUNCT
brj-23874	6	9	bioresources	bioresource	NOUN
brj-23874	6	10	21(1	21(1	NUM
brj-23874	6	11	)	)	PUNCT
brj-23874	6	12	,	,	PUNCT
brj-23874	6	13	116	116	NUM
brj-23874	6	14	-	-	SYM
brj-23874	6	15	127	127	NUM
brj-23874	6	16	.	.	PUNCT
brj-23874	7	1	116	116	NUM
brj-23874	7	2	preparation	preparation	NOUN
brj-23874	7	3	of	of	ADP
brj-23874	7	4	citrullus	citrullus	PROPN
brj-23874	7	5	colocynthis	colocynthis	NOUN
brj-23874	7	6	seed	seed	NOUN
brj-23874	7	7	extract	extract	NOUN
brj-23874	7	8	and	and	CCONJ
brj-23874	7	9	assessment	assessment	NOUN
brj-23874	7	10	of	of	ADP
brj-23874	7	11	cyto	cyto	NOUN
brj-23874	7	12	-	-	PUNCT
brj-23874	7	13	toxicity	toxicity	NOUN
brj-23874	7	14	,	,	PUNCT
brj-23874	7	15	anti	anti	ADJ
brj-23874	7	16	-	-	ADJ
brj-23874	7	17	microbial	microbial	ADJ
brj-23874	7	18	,	,	PUNCT
brj-23874	7	19	anti	anti	ADJ
brj-23874	7	20	-	-	ADJ
brj-23874	7	21	inflammatory	inflammatory	ADJ
brj-23874	7	22	,	,	PUNCT
brj-23874	7	23	and	and	CCONJ
brj-23874	7	24	analgesic	analgesic	ADJ
brj-23874	7	25	activities	activity	NOUN
brj-23874	7	26	zihan	zihan	PROPN
brj-23874	7	27	zhu	zhu	PROPN
brj-23874	7	28	,	,	PUNCT
brj-23874	7	29	a	a	DET
brj-23874	7	30	jie	jie	PROPN
brj-23874	7	31	zhang	zhang	PROPN
brj-23874	7	32	,	,	PUNCT
brj-23874	7	33	b	b	PROPN
brj-23874	7	34	,	,	PUNCT
brj-23874	7	35	*	*	PUNCT
brj-23874	7	36	and	and	CCONJ
brj-23874	7	37	huan	huan	PROPN
brj-23874	7	38	meng	meng	PROPN
brj-23874	7	39	c	c	PROPN
brj-23874	7	40	,	,	PUNCT
brj-23874	7	41	*	*	PUNCT
brj-23874	7	42	one	one	NUM
brj-23874	7	43	of	of	ADP
brj-23874	7	44	the	the	DET
brj-23874	7	45	most	most	ADV
brj-23874	7	46	common	common	ADJ
brj-23874	7	47	health	health	NOUN
brj-23874	7	48	issues	issue	NOUN
brj-23874	7	49	that	that	PRON
brj-23874	7	50	affect	affect	VERB
brj-23874	7	51	individuals	individual	NOUN
brj-23874	7	52	is	be	AUX
brj-23874	7	53	pain	pain	NOUN
brj-23874	7	54	,	,	PUNCT
brj-23874	7	55	which	which	PRON
brj-23874	7	56	can	can	AUX
brj-23874	7	57	manifest	manifest	VERB
brj-23874	7	58	in	in	ADP
brj-23874	7	59	a	a	DET
brj-23874	7	60	variety	variety	NOUN
brj-23874	7	61	of	of	ADP
brj-23874	7	62	ways	way	NOUN
brj-23874	7	63	.	.	PUNCT
brj-23874	8	1	opioids	opioid	NOUN
brj-23874	8	2	and	and	CCONJ
brj-23874	8	3	nonsteroidal	nonsteroidal	NOUN
brj-23874	8	4	antiinflammatory	antiinflammatory	NOUN
brj-23874	8	5	medications	medication	NOUN
brj-23874	8	6	(	(	PUNCT
brj-23874	8	7	nsaids	nsaid	NOUN
brj-23874	8	8	)	)	PUNCT
brj-23874	8	9	are	be	AUX
brj-23874	8	10	frequently	frequently	ADV
brj-23874	8	11	prescribed	prescribe	VERB
brj-23874	8	12	for	for	ADP
brj-23874	8	13	pain	pain	NOUN
brj-23874	8	14	relief	relief	NOUN
brj-23874	8	15	;	;	PUNCT
brj-23874	8	16	however	however	ADV
brj-23874	8	17	,	,	PUNCT
brj-23874	8	18	their	their	PRON
brj-23874	8	19	prolonged	prolong	VERB
brj-23874	8	20	use	use	NOUN
brj-23874	8	21	can	can	AUX
brj-23874	8	22	result	result	VERB
brj-23874	8	23	in	in	ADP
brj-23874	8	24	substantial	substantial	ADJ
brj-23874	8	25	adverse	adverse	ADJ
brj-23874	8	26	effects	effect	NOUN
brj-23874	8	27	on	on	ADP
brj-23874	8	28	various	various	ADJ
brj-23874	8	29	bodily	bodily	ADJ
brj-23874	8	30	systems	system	NOUN
brj-23874	8	31	.	.	PUNCT
brj-23874	9	1	as	as	ADP
brj-23874	9	2	a	a	DET
brj-23874	9	3	result	result	NOUN
brj-23874	9	4	,	,	PUNCT
brj-23874	9	5	it	it	PRON
brj-23874	9	6	is	be	AUX
brj-23874	9	7	important	important	ADJ
brj-23874	9	8	to	to	PART
brj-23874	9	9	identify	identify	VERB
brj-23874	9	10	alternative	alternative	ADJ
brj-23874	9	11	medications	medication	NOUN
brj-23874	9	12	that	that	PRON
brj-23874	9	13	are	be	AUX
brj-23874	9	14	both	both	CCONJ
brj-23874	9	15	more	more	ADV
brj-23874	9	16	effective	effective	ADJ
brj-23874	9	17	and	and	CCONJ
brj-23874	9	18	secure	secure	ADJ
brj-23874	9	19	.	.	PUNCT
brj-23874	10	1	the	the	DET
brj-23874	10	2	health	health	NOUN
brj-23874	10	3	benefits	benefit	NOUN
brj-23874	10	4	of	of	ADP
brj-23874	10	5	citrullus	citrullus	PROPN
brj-23874	10	6	colocynthis	colocynthis	PROPN
brj-23874	10	7	herb	herb	NOUN
brj-23874	10	8	,	,	PUNCT
brj-23874	10	9	rich	rich	ADJ
brj-23874	10	10	in	in	ADP
brj-23874	10	11	beneficial	beneficial	ADJ
brj-23874	10	12	elements	element	NOUN
brj-23874	10	13	,	,	PUNCT
brj-23874	10	14	are	be	AUX
brj-23874	10	15	well	well	ADV
brj-23874	10	16	documented	document	VERB
brj-23874	10	17	.	.	PUNCT
brj-23874	11	1	the	the	DET
brj-23874	11	2	effects	effect	NOUN
brj-23874	11	3	of	of	ADP
brj-23874	11	4	an	an	DET
brj-23874	11	5	aqueous	aqueous	ADJ
brj-23874	11	6	seed	seed	NOUN
brj-23874	11	7	extract	extract	NOUN
brj-23874	11	8	of	of	ADP
brj-23874	11	9	c.	c.	PROPN
brj-23874	11	10	colocynthis	colocynthis	PROPN
brj-23874	11	11	were	be	AUX
brj-23874	11	12	examined	examine	VERB
brj-23874	11	13	in	in	ADP
brj-23874	11	14	this	this	DET
brj-23874	11	15	study	study	NOUN
brj-23874	11	16	.	.	PUNCT
brj-23874	12	1	the	the	DET
brj-23874	12	2	b16f10	b16f10	ADJ
brj-23874	12	3	melanoma	melanoma	NOUN
brj-23874	12	4	cell	cell	NOUN
brj-23874	12	5	line	line	NOUN
brj-23874	12	6	was	be	AUX
brj-23874	12	7	employed	employ	VERB
brj-23874	12	8	to	to	PART
brj-23874	12	9	evaluate	evaluate	VERB
brj-23874	12	10	the	the	DET
brj-23874	12	11	extract	extract	NOUN
brj-23874	12	12	’s	’s	PART
brj-23874	12	13	cytotoxicity	cytotoxicity	NOUN
brj-23874	12	14	.	.	PUNCT
brj-23874	13	1	the	the	DET
brj-23874	13	2	authors	author	NOUN
brj-23874	13	3	implemented	implement	VERB
brj-23874	13	4	antimicrobial	antimicrobial	ADJ
brj-23874	13	5	investigations	investigation	NOUN
brj-23874	13	6	employing	employ	VERB
brj-23874	13	7	four	four	NUM
brj-23874	13	8	bacterial	bacterial	ADJ
brj-23874	13	9	strains	strain	NOUN
brj-23874	13	10	.	.	PUNCT
brj-23874	14	1	the	the	DET
brj-23874	14	2	anti	anti	ADJ
brj-23874	14	3	-	-	ADJ
brj-23874	14	4	inflammatory	inflammatory	ADJ
brj-23874	14	5	and	and	CCONJ
brj-23874	14	6	analgesic	analgesic	ADJ
brj-23874	14	7	activities	activity	NOUN
brj-23874	14	8	were	be	AUX
brj-23874	14	9	assessed	assess	VERB
brj-23874	14	10	using	use	VERB
brj-23874	14	11	swiss	swiss	ADJ
brj-23874	14	12	albino	albino	NOUN
brj-23874	14	13	mice	mouse	NOUN
brj-23874	14	14	and	and	CCONJ
brj-23874	14	15	wistar	wistar	PROPN
brj-23874	14	16	albino	albino	NOUN
brj-23874	14	17	rats	rat	NOUN
brj-23874	14	18	,	,	PUNCT
brj-23874	14	19	respectively	respectively	ADV
brj-23874	14	20	.	.	PUNCT
brj-23874	15	1	the	the	DET
brj-23874	15	2	cytotoxicity	cytotoxicity	NOUN
brj-23874	15	3	analysis	analysis	NOUN
brj-23874	15	4	demonstrated	demonstrate	VERB
brj-23874	15	5	that	that	SCONJ
brj-23874	15	6	the	the	DET
brj-23874	15	7	c.	c.	PROPN
brj-23874	15	8	colocynthis	colocynthis	PROPN
brj-23874	15	9	extract	extract	NOUN
brj-23874	15	10	did	do	AUX
brj-23874	15	11	not	not	PART
brj-23874	15	12	manifest	manifest	VERB
brj-23874	15	13	any	any	DET
brj-23874	15	14	significant	significant	ADJ
brj-23874	15	15	cytotoxic	cytotoxic	ADJ
brj-23874	15	16	effects	effect	NOUN
brj-23874	15	17	on	on	ADP
brj-23874	15	18	the	the	DET
brj-23874	15	19	b16f10	b16f10	ADJ
brj-23874	15	20	melanoma	melanoma	NOUN
brj-23874	15	21	cell	cell	NOUN
brj-23874	15	22	line	line	NOUN
brj-23874	15	23	.	.	PUNCT
brj-23874	16	1	the	the	DET
brj-23874	16	2	extract	extract	NOUN
brj-23874	16	3	exhibited	exhibit	VERB
brj-23874	16	4	efficacious	efficacious	ADJ
brj-23874	16	5	activity	activity	NOUN
brj-23874	16	6	against	against	ADP
brj-23874	16	7	the	the	DET
brj-23874	16	8	gram	gram	NOUN
brj-23874	16	9	-	-	PUNCT
brj-23874	16	10	positive	positive	ADJ
brj-23874	16	11	bacteria	bacteria	NOUN
brj-23874	16	12	that	that	PRON
brj-23874	16	13	were	be	AUX
brj-23874	16	14	the	the	DET
brj-23874	16	15	subject	subject	NOUN
brj-23874	16	16	of	of	ADP
brj-23874	16	17	antimicrobial	antimicrobial	ADJ
brj-23874	16	18	investigations	investigation	NOUN
brj-23874	16	19	.	.	PUNCT
brj-23874	17	1	pain	pain	NOUN
brj-23874	17	2	inhibition	inhibition	NOUN
brj-23874	17	3	effects	effect	NOUN
brj-23874	17	4	exceeded	exceed	VERB
brj-23874	17	5	70	70	NUM
brj-23874	17	6	%	%	NOUN
brj-23874	17	7	,	,	PUNCT
brj-23874	17	8	with	with	ADP
brj-23874	17	9	the	the	DET
brj-23874	17	10	analgesic	analgesic	ADJ
brj-23874	17	11	activity	activity	NOUN
brj-23874	17	12	.	.	PUNCT
brj-23874	18	1	consequently	consequently	ADV
brj-23874	18	2	,	,	PUNCT
brj-23874	18	3	the	the	DET
brj-23874	18	4	c.	c.	PROPN
brj-23874	18	5	colocynthis	colocynthis	PROPN
brj-23874	18	6	extract	extract	VERB
brj-23874	18	7	exhibits	exhibit	VERB
brj-23874	18	8	potential	potential	NOUN
brj-23874	18	9	as	as	ADP
brj-23874	18	10	an	an	DET
brj-23874	18	11	analgesic	analgesic	ADJ
brj-23874	18	12	and	and	CCONJ
brj-23874	18	13	antimicrobial	antimicrobial	ADJ
brj-23874	18	14	agent	agent	NOUN
brj-23874	18	15	,	,	PUNCT
brj-23874	18	16	necessitating	necessitate	VERB
brj-23874	18	17	additional	additional	ADJ
brj-23874	18	18	research	research	NOUN
brj-23874	18	19	and	and	CCONJ
brj-23874	18	20	development	development	NOUN
brj-23874	18	21	work	work	NOUN
brj-23874	18	22	.	.	PUNCT
brj-23874	19	1	doi	doi	NOUN
brj-23874	19	2	:	:	PUNCT
brj-23874	19	3	10.15376	10.15376	NUM
brj-23874	19	4	/	/	SYM
brj-23874	19	5	biores.21.1.116	biores.21.1.116	NOUN
brj-23874	19	6	-	-	SYM
brj-23874	19	7	127	127	NUM
brj-23874	19	8	keywords	keyword	NOUN
brj-23874	19	9	:	:	PUNCT
brj-23874	19	10	citrullus	citrullus	PROPN
brj-23874	19	11	colocynthis	colocynthis	NOUN
brj-23874	19	12	;	;	PUNCT
brj-23874	19	13	cytotoxicity	cytotoxicity	NOUN
brj-23874	19	14	;	;	PUNCT
brj-23874	19	15	anti	anti	ADJ
brj-23874	19	16	-	-	ADJ
brj-23874	19	17	microbial	microbial	ADJ
brj-23874	19	18	;	;	PUNCT
brj-23874	19	19	analgesic	analgesic	ADJ
brj-23874	19	20	;	;	PUNCT
brj-23874	19	21	anti	anti	ADJ
brj-23874	19	22	-	-	ADJ
brj-23874	19	23	inflammatory	inflammatory	ADJ
brj-23874	19	24	contact	contact	NOUN
brj-23874	19	25	information	information	NOUN
brj-23874	19	26	a	a	DET
brj-23874	19	27	:	:	PUNCT
brj-23874	19	28	pharmaceutical	pharmaceutical	ADJ
brj-23874	19	29	sciences	science	NOUN
brj-23874	19	30	,	,	PUNCT
brj-23874	19	31	xi’an	xi’an	PROPN
brj-23874	19	32	jiaotong	jiaotong	PROPN
brj-23874	19	33	-	-	PUNCT
brj-23874	19	34	liverpool	liverpool	PROPN
brj-23874	19	35	university	university	NOUN
brj-23874	19	36	;	;	PUNCT
brj-23874	19	37	b	b	X
brj-23874	19	38	:	:	PUNCT
brj-23874	19	39	department	department	NOUN
brj-23874	19	40	of	of	ADP
brj-23874	19	41	anesthesiology	anesthesiology	NOUN
brj-23874	19	42	,	,	PUNCT
brj-23874	19	43	shanghai	shanghai	PROPN
brj-23874	19	44	huashan	huashan	PROPN
brj-23874	19	45	hospital	hospital	PROPN
brj-23874	19	46	fudan	fudan	PROPN
brj-23874	19	47	university	university	PROPN
brj-23874	19	48	baoshan	baoshan	PROPN
brj-23874	19	49	clinic	clinic	PROPN
brj-23874	19	50	;	;	PUNCT
brj-23874	19	51	c	c	X
brj-23874	19	52	:	:	PUNCT
brj-23874	19	53	department	department	NOUN
brj-23874	19	54	of	of	ADP
brj-23874	19	55	ophthalmology	ophthalmology	NOUN
brj-23874	19	56	,	,	PUNCT
brj-23874	19	57	yanbian	yanbian	ADJ
brj-23874	19	58	hospital	hospital	NOUN
brj-23874	19	59	;	;	PUNCT
brj-23874	19	60	*	*	PUNCT
brj-23874	19	61	corresponding	correspond	VERB
brj-23874	19	62	authors	author	NOUN
brj-23874	19	63	:	:	PUNCT
brj-23874	19	64	jiezhangj99@hotmail.com	jiezhangj99@hotmail.com	X
brj-23874	19	65	;	;	PUNCT
brj-23874	19	66	15526771260@163.com	15526771260@163.com	NUM
brj-23874	19	67	introduction	introduction	NOUN
brj-23874	19	68	the	the	DET
brj-23874	19	69	most	most	ADV
brj-23874	19	70	common	common	ADJ
brj-23874	19	71	human	human	ADJ
brj-23874	19	72	condition	condition	NOUN
brj-23874	19	73	known	know	VERB
brj-23874	19	74	to	to	ADP
brj-23874	19	75	science	science	NOUN
brj-23874	19	76	is	be	AUX
brj-23874	19	77	pain	pain	NOUN
brj-23874	19	78	in	in	ADP
brj-23874	19	79	all	all	DET
brj-23874	19	80	its	its	PRON
brj-23874	19	81	forms	form	NOUN
brj-23874	19	82	.	.	PUNCT
brj-23874	20	1	one	one	NUM
brj-23874	20	2	in	in	ADP
brj-23874	20	3	five	five	NUM
brj-23874	20	4	individuals	individual	NOUN
brj-23874	20	5	globally	globally	ADV
brj-23874	20	6	experiences	experience	VERB
brj-23874	20	7	chronic	chronic	ADJ
brj-23874	20	8	pain	pain	NOUN
brj-23874	20	9	,	,	PUNCT
brj-23874	20	10	one	one	NUM
brj-23874	20	11	in	in	ADP
brj-23874	20	12	ten	ten	NUM
brj-23874	20	13	adults	adult	NOUN
brj-23874	20	14	receives	receive	VERB
brj-23874	20	15	a	a	DET
brj-23874	20	16	diagnosis	diagnosis	NOUN
brj-23874	20	17	each	each	DET
brj-23874	20	18	year	year	NOUN
brj-23874	20	19	according	accord	VERB
brj-23874	20	20	to	to	ADP
brj-23874	20	21	the	the	DET
brj-23874	20	22	international	international	ADJ
brj-23874	20	23	association	association	NOUN
brj-23874	20	24	for	for	ADP
brj-23874	20	25	the	the	DET
brj-23874	20	26	study	study	NOUN
brj-23874	20	27	of	of	ADP
brj-23874	20	28	pain	pain	NOUN
brj-23874	20	29	(	(	PUNCT
brj-23874	20	30	iasp	iasp	NOUN
brj-23874	20	31	2012	2012	NUM
brj-23874	20	32	)	)	PUNCT
brj-23874	20	33	,	,	PUNCT
brj-23874	20	34	and	and	CCONJ
brj-23874	20	35	roughly	roughly	ADV
brj-23874	20	36	one	one	NUM
brj-23874	20	37	in	in	ADP
brj-23874	20	38	nine	nine	NUM
brj-23874	20	39	young	young	ADJ
brj-23874	20	40	adults	adult	NOUN
brj-23874	20	41	deal	deal	VERB
brj-23874	20	42	with	with	ADP
brj-23874	20	43	chronic	chronic	ADJ
brj-23874	20	44	pain	pain	NOUN
brj-23874	20	45	(	(	PUNCT
brj-23874	20	46	murray	murray	PROPN
brj-23874	20	47	et	et	PROPN
brj-23874	20	48	al	al	PROPN
brj-23874	20	49	.	.	PROPN
brj-23874	20	50	2022	2022	NUM
brj-23874	20	51	)	)	PUNCT
brj-23874	20	52	.	.	PUNCT
brj-23874	21	1	depending	depend	VERB
brj-23874	21	2	on	on	ADP
brj-23874	21	3	the	the	DET
brj-23874	21	4	nature	nature	NOUN
brj-23874	21	5	of	of	ADP
brj-23874	21	6	pain	pain	NOUN
brj-23874	21	7	and	and	CCONJ
brj-23874	21	8	the	the	DET
brj-23874	21	9	variety	variety	NOUN
brj-23874	21	10	of	of	ADP
brj-23874	21	11	research	research	NOUN
brj-23874	21	12	done	do	VERB
brj-23874	21	13	,	,	PUNCT
brj-23874	21	14	children	child	NOUN
brj-23874	21	15	experience	experience	VERB
brj-23874	21	16	pain	pain	NOUN
brj-23874	21	17	anywhere	anywhere	ADV
brj-23874	21	18	from	from	ADP
brj-23874	21	19	11	11	NUM
brj-23874	21	20	%	%	NOUN
brj-23874	21	21	to	to	ADP
brj-23874	21	22	38	38	NUM
brj-23874	21	23	%	%	NOUN
brj-23874	21	24	of	of	ADP
brj-23874	21	25	the	the	DET
brj-23874	21	26	time	time	NOUN
brj-23874	21	27	(	(	PUNCT
brj-23874	21	28	sakurai	sakurai	NOUN
brj-23874	21	29	et	et	NOUN
brj-23874	21	30	al	al	PROPN
brj-23874	21	31	2015	2015	NUM
brj-23874	21	32	)	)	PUNCT
brj-23874	21	33	.	.	PUNCT
brj-23874	22	1	this	this	DET
brj-23874	22	2	information	information	NOUN
brj-23874	22	3	emphasizes	emphasize	VERB
brj-23874	22	4	how	how	SCONJ
brj-23874	22	5	important	important	ADJ
brj-23874	22	6	pain	pain	NOUN
brj-23874	22	7	is	be	AUX
brj-23874	22	8	as	as	ADP
brj-23874	22	9	a	a	DET
brj-23874	22	10	major	major	ADJ
brj-23874	22	11	health	health	NOUN
brj-23874	22	12	concern	concern	NOUN
brj-23874	22	13	worldwide	worldwide	ADV
brj-23874	22	14	.	.	PUNCT
brj-23874	23	1	one	one	NUM
brj-23874	23	2	of	of	ADP
brj-23874	23	3	the	the	DET
brj-23874	23	4	main	main	ADJ
brj-23874	23	5	signs	sign	NOUN
brj-23874	23	6	of	of	ADP
brj-23874	23	7	inflammation	inflammation	NOUN
brj-23874	23	8	is	be	AUX
brj-23874	23	9	pain	pain	NOUN
brj-23874	23	10	,	,	PUNCT
brj-23874	23	11	which	which	PRON
brj-23874	23	12	also	also	ADV
brj-23874	23	13	manifests	manifest	VERB
brj-23874	23	14	as	as	ADP
brj-23874	23	15	redness	redness	NOUN
brj-23874	23	16	,	,	PUNCT
brj-23874	23	17	warmth	warmth	NOUN
brj-23874	23	18	,	,	PUNCT
brj-23874	23	19	swelling	swelling	NOUN
brj-23874	23	20	,	,	PUNCT
brj-23874	23	21	and	and	CCONJ
brj-23874	23	22	decreased	decrease	VERB
brj-23874	23	23	function	function	NOUN
brj-23874	23	24	,	,	PUNCT
brj-23874	23	25	all	all	PRON
brj-23874	23	26	of	of	ADP
brj-23874	23	27	which	which	PRON
brj-23874	23	28	together	together	ADV
brj-23874	23	29	define	define	VERB
brj-23874	23	30	a	a	DET
brj-23874	23	31	typical	typical	ADJ
brj-23874	23	32	inflammatory	inflammatory	ADJ
brj-23874	23	33	response	response	NOUN
brj-23874	23	34	.	.	PUNCT
brj-23874	24	1	though	though	SCONJ
brj-23874	24	2	inflammation	inflammation	NOUN
brj-23874	24	3	is	be	AUX
brj-23874	24	4	essential	essential	ADJ
brj-23874	24	5	to	to	ADP
brj-23874	24	6	the	the	DET
brj-23874	24	7	body	body	NOUN
brj-23874	24	8	’s	’s	PART
brj-23874	24	9	natural	natural	ADJ
brj-23874	24	10	equilibrium	equilibrium	NOUN
brj-23874	24	11	processes	process	NOUN
brj-23874	24	12	,	,	PUNCT
brj-23874	24	13	its	its	PRON
brj-23874	24	14	effects	effect	NOUN
brj-23874	24	15	can	can	AUX
brj-23874	24	16	occasionally	occasionally	ADV
brj-23874	24	17	go	go	VERB
brj-23874	24	18	well	well	ADV
brj-23874	24	19	beyond	beyond	ADP
brj-23874	24	20	preserving	preserve	VERB
brj-23874	24	21	equilibrium	equilibrium	NOUN
brj-23874	24	22	,	,	PUNCT
brj-23874	24	23	as	as	SCONJ
brj-23874	24	24	it	it	PRON
brj-23874	24	25	can	can	AUX
brj-23874	24	26	peer	peer	NOUN
brj-23874	24	27	-	-	PUNCT
brj-23874	24	28	reviewed	review	VERB
brj-23874	24	29	article	article	NOUN
brj-23874	24	30	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	24	31	zhu	zhu	PROPN
brj-23874	24	32	et	et	PROPN
brj-23874	24	33	al	al	PROPN
brj-23874	24	34	.	.	PROPN
brj-23874	25	1	(	(	PUNCT
brj-23874	25	2	2026	2026	NUM
brj-23874	25	3	)	)	PUNCT
brj-23874	25	4	.	.	PUNCT
brj-23874	26	1	“	"	PUNCT
brj-23874	26	2	pain	pain	NOUN
brj-23874	26	3	control	control	NOUN
brj-23874	26	4	with	with	ADP
brj-23874	26	5	seed	seed	NOUN
brj-23874	26	6	extract	extract	NOUN
brj-23874	26	7	,	,	PUNCT
brj-23874	26	8	”	"	PUNCT
brj-23874	26	9	bioresources	bioresource	NOUN
brj-23874	26	10	21(1	21(1	NUM
brj-23874	26	11	)	)	PUNCT
brj-23874	26	12	,	,	PUNCT
brj-23874	26	13	116	116	NUM
brj-23874	26	14	-	-	SYM
brj-23874	26	15	127	127	NUM
brj-23874	26	16	.	.	PUNCT
brj-23874	27	1	117	117	NUM
brj-23874	27	2	lower	low	ADJ
brj-23874	27	3	pain	pain	NOUN
brj-23874	27	4	thresholds	threshold	NOUN
brj-23874	27	5	and	and	CCONJ
brj-23874	27	6	increase	increase	VERB
brj-23874	27	7	sensitivity	sensitivity	NOUN
brj-23874	27	8	to	to	ADP
brj-23874	27	9	pain	pain	NOUN
brj-23874	27	10	(	(	PUNCT
brj-23874	27	11	clinkard	clinkard	NOUN
brj-23874	27	12	et	et	PROPN
brj-23874	27	13	al	al	PROPN
brj-23874	27	14	2024	2024	NUM
brj-23874	27	15	;	;	PUNCT
brj-23874	27	16	zhang	zhang	PROPN
brj-23874	27	17	et	et	PROPN
brj-23874	27	18	al	al	PROPN
brj-23874	27	19	2023	2023	NUM
brj-23874	27	20	)	)	PUNCT
brj-23874	27	21	.	.	PUNCT
brj-23874	28	1	medications	medication	NOUN
brj-23874	28	2	,	,	PUNCT
brj-23874	28	3	such	such	ADJ
brj-23874	28	4	as	as	ADP
brj-23874	28	5	opioid	opioid	ADJ
brj-23874	28	6	pain	pain	NOUN
brj-23874	28	7	relievers	reliever	NOUN
brj-23874	28	8	and	and	CCONJ
brj-23874	28	9	non	non	ADJ
brj-23874	28	10	-	-	ADJ
brj-23874	28	11	steroidal	steroidal	ADJ
brj-23874	28	12	anti	anti	ADJ
brj-23874	28	13	-	-	ADJ
brj-23874	28	14	inflammatory	inflammatory	ADJ
brj-23874	28	15	medications	medication	NOUN
brj-23874	28	16	(	(	PUNCT
brj-23874	28	17	nsaids	nsaid	NOUN
brj-23874	28	18	)	)	PUNCT
brj-23874	28	19	,	,	PUNCT
brj-23874	28	20	are	be	AUX
brj-23874	28	21	frequently	frequently	ADV
brj-23874	28	22	used	use	VERB
brj-23874	28	23	to	to	PART
brj-23874	28	24	treat	treat	VERB
brj-23874	28	25	pain	pain	NOUN
brj-23874	28	26	.	.	PUNCT
brj-23874	29	1	although	although	SCONJ
brj-23874	29	2	these	these	DET
brj-23874	29	3	drugs	drug	NOUN
brj-23874	29	4	greatly	greatly	ADV
brj-23874	29	5	help	help	VERB
brj-23874	29	6	with	with	ADP
brj-23874	29	7	the	the	DET
brj-23874	29	8	management	management	NOUN
brj-23874	29	9	of	of	ADP
brj-23874	29	10	pain	pain	NOUN
brj-23874	29	11	,	,	PUNCT
brj-23874	29	12	some	some	DET
brj-23874	29	13	people	people	NOUN
brj-23874	29	14	may	may	AUX
brj-23874	29	15	experience	experience	VERB
brj-23874	29	16	severe	severe	ADJ
brj-23874	29	17	negative	negative	ADJ
brj-23874	29	18	effects	effect	NOUN
brj-23874	29	19	from	from	ADP
brj-23874	29	20	them	they	PRON
brj-23874	29	21	.	.	PUNCT
brj-23874	30	1	high	high	ADJ
brj-23874	30	2	blood	blood	NOUN
brj-23874	30	3	sugar	sugar	NOUN
brj-23874	30	4	,	,	PUNCT
brj-23874	30	5	gastrointestinal	gastrointestinal	ADJ
brj-23874	30	6	tract	tract	NOUN
brj-23874	30	7	irritation	irritation	NOUN
brj-23874	30	8	,	,	PUNCT
brj-23874	30	9	heart	heart	NOUN
brj-23874	30	10	problems	problem	NOUN
brj-23874	30	11	,	,	PUNCT
brj-23874	30	12	liver	liver	NOUN
brj-23874	30	13	toxicity	toxicity	NOUN
brj-23874	30	14	,	,	PUNCT
brj-23874	30	15	and	and	CCONJ
brj-23874	30	16	elevated	elevated	ADJ
brj-23874	30	17	toxicity	toxicity	NOUN
brj-23874	30	18	risks	risk	NOUN
brj-23874	30	19	,	,	PUNCT
brj-23874	30	20	especially	especially	ADV
brj-23874	30	21	in	in	ADP
brj-23874	30	22	older	old	ADJ
brj-23874	30	23	persons	person	NOUN
brj-23874	30	24	,	,	PUNCT
brj-23874	30	25	are	be	AUX
brj-23874	30	26	common	common	ADJ
brj-23874	30	27	adverse	adverse	ADJ
brj-23874	30	28	responses	response	NOUN
brj-23874	30	29	(	(	PUNCT
brj-23874	30	30	schofield	schofield	PROPN
brj-23874	30	31	et	et	PROPN
brj-23874	30	32	al	al	PROPN
brj-23874	30	33	2019	2019	NUM
brj-23874	30	34	)	)	PUNCT
brj-23874	30	35	.	.	PUNCT
brj-23874	31	1	despite	despite	SCONJ
brj-23874	31	2	extensive	extensive	ADJ
brj-23874	31	3	research	research	NOUN
brj-23874	31	4	on	on	ADP
brj-23874	31	5	conventional	conventional	ADJ
brj-23874	31	6	pain	pain	NOUN
brj-23874	31	7	management	management	NOUN
brj-23874	31	8	strategies	strategy	NOUN
brj-23874	31	9	,	,	PUNCT
brj-23874	31	10	such	such	ADJ
brj-23874	31	11	as	as	ADP
brj-23874	31	12	the	the	DET
brj-23874	31	13	use	use	NOUN
brj-23874	31	14	of	of	ADP
brj-23874	31	15	nsaids	nsaid	NOUN
brj-23874	31	16	and	and	CCONJ
brj-23874	31	17	opioids	opioid	NOUN
brj-23874	31	18	,	,	PUNCT
brj-23874	31	19	significant	significant	ADJ
brj-23874	31	20	challenges	challenge	NOUN
brj-23874	31	21	persist	persist	VERB
brj-23874	31	22	,	,	PUNCT
brj-23874	31	23	including	include	VERB
brj-23874	31	24	adverse	adverse	ADJ
brj-23874	31	25	side	side	NOUN
brj-23874	31	26	effects	effect	NOUN
brj-23874	31	27	,	,	PUNCT
brj-23874	31	28	risks	risk	NOUN
brj-23874	31	29	of	of	ADP
brj-23874	31	30	dependency	dependency	NOUN
brj-23874	31	31	,	,	PUNCT
brj-23874	31	32	and	and	CCONJ
brj-23874	31	33	limited	limited	ADJ
brj-23874	31	34	efficacy	efficacy	NOUN
brj-23874	31	35	in	in	ADP
brj-23874	31	36	certain	certain	ADJ
brj-23874	31	37	populations	population	NOUN
brj-23874	31	38	.	.	PUNCT
brj-23874	32	1	(	(	PUNCT
brj-23874	32	2	bennett	bennett	PROPN
brj-23874	32	3	et	et	PROPN
brj-23874	32	4	al	al	PROPN
brj-23874	32	5	2024	2024	NUM
brj-23874	32	6	)	)	PUNCT
brj-23874	32	7	.	.	PUNCT
brj-23874	33	1	exploring	explore	VERB
brj-23874	33	2	natural	natural	ADJ
brj-23874	33	3	substitutes	substitute	NOUN
brj-23874	33	4	has	have	AUX
brj-23874	33	5	therefore	therefore	ADV
brj-23874	33	6	proved	prove	VERB
brj-23874	33	7	to	to	PART
brj-23874	33	8	be	be	AUX
brj-23874	33	9	a	a	DET
brj-23874	33	10	wise	wise	ADJ
brj-23874	33	11	course	course	NOUN
brj-23874	33	12	of	of	ADP
brj-23874	33	13	action	action	NOUN
brj-23874	33	14	.	.	PUNCT
brj-23874	34	1	furthermore	furthermore	ADV
brj-23874	34	2	,	,	PUNCT
brj-23874	34	3	while	while	SCONJ
brj-23874	34	4	natural	natural	ADJ
brj-23874	34	5	substitutes	substitute	NOUN
brj-23874	34	6	such	such	ADJ
brj-23874	34	7	as	as	ADP
brj-23874	34	8	citrullus	citrullus	PROPN
brj-23874	34	9	colocynthis	colocynthis	NOUN
brj-23874	34	10	have	have	AUX
brj-23874	34	11	demonstrated	demonstrate	VERB
brj-23874	34	12	promising	promise	VERB
brj-23874	34	13	pharmacological	pharmacological	ADJ
brj-23874	34	14	properties	property	NOUN
brj-23874	34	15	,	,	PUNCT
brj-23874	34	16	including	include	VERB
brj-23874	34	17	analgesic	analgesic	ADJ
brj-23874	34	18	,	,	PUNCT
brj-23874	34	19	anti	anti	ADJ
brj-23874	34	20	-	-	ADJ
brj-23874	34	21	inflammatory	inflammatory	ADJ
brj-23874	34	22	,	,	PUNCT
brj-23874	34	23	and	and	CCONJ
brj-23874	34	24	antioxidant	antioxidant	ADJ
brj-23874	34	25	effects	effect	NOUN
brj-23874	34	26	,	,	PUNCT
brj-23874	34	27	comprehensive	comprehensive	ADJ
brj-23874	34	28	evaluations	evaluation	NOUN
brj-23874	34	29	of	of	ADP
brj-23874	34	30	its	its	PRON
brj-23874	34	31	bioactive	bioactive	ADJ
brj-23874	34	32	components	component	NOUN
brj-23874	34	33	in	in	ADP
brj-23874	34	34	advanced	advanced	ADJ
brj-23874	34	35	experimental	experimental	ADJ
brj-23874	34	36	models	model	NOUN
brj-23874	34	37	remain	remain	VERB
brj-23874	34	38	incomplete	incomplete	ADJ
brj-23874	34	39	(	(	PUNCT
brj-23874	34	40	rao	rao	NOUN
brj-23874	34	41	and	and	CCONJ
brj-23874	34	42	poonia	poonia	PROPN
brj-23874	34	43	2023	2023	NUM
brj-23874	34	44	)	)	PUNCT
brj-23874	34	45	.	.	PUNCT
brj-23874	35	1	it	it	PRON
brj-23874	35	2	is	be	AUX
brj-23874	35	3	a	a	DET
brj-23874	35	4	desert	desert	NOUN
brj-23874	35	5	plant	plant	NOUN
brj-23874	35	6	that	that	PRON
brj-23874	35	7	has	have	VERB
brj-23874	35	8	great	great	ADJ
brj-23874	35	9	therapeutic	therapeutic	ADJ
brj-23874	35	10	potential	potential	NOUN
brj-23874	35	11	due	due	ADP
brj-23874	35	12	to	to	ADP
brj-23874	35	13	its	its	PRON
brj-23874	35	14	abundance	abundance	NOUN
brj-23874	35	15	of	of	ADP
brj-23874	35	16	bioactive	bioactive	ADJ
brj-23874	35	17	components	component	NOUN
brj-23874	35	18	,	,	PUNCT
brj-23874	35	19	including	include	VERB
brj-23874	35	20	glycosides	glycoside	NOUN
brj-23874	35	21	,	,	PUNCT
brj-23874	35	22	fatty	fatty	NOUN
brj-23874	35	23	acids	acid	NOUN
brj-23874	35	24	,	,	PUNCT
brj-23874	35	25	alkaloids	alkaloid	NOUN
brj-23874	35	26	,	,	PUNCT
brj-23874	35	27	flavonoids	flavonoid	NOUN
brj-23874	35	28	(	(	PUNCT
brj-23874	35	29	kim	kim	PROPN
brj-23874	35	30	et	et	PROPN
brj-23874	35	31	al	al	PROPN
brj-23874	35	32	2022	2022	NUM
brj-23874	35	33	)	)	PUNCT
brj-23874	35	34	,	,	PUNCT
brj-23874	35	35	and	and	CCONJ
brj-23874	35	36	essential	essential	ADJ
brj-23874	35	37	oils	oil	NOUN
brj-23874	35	38	.	.	PUNCT
brj-23874	36	1	it	it	PRON
brj-23874	36	2	is	be	AUX
brj-23874	36	3	well	well	ADV
brj-23874	36	4	known	know	VERB
brj-23874	36	5	that	that	SCONJ
brj-23874	36	6	this	this	DET
brj-23874	36	7	plant	plant	NOUN
brj-23874	36	8	strengthens	strengthen	VERB
brj-23874	36	9	immunity	immunity	NOUN
brj-23874	36	10	.	.	PUNCT
brj-23874	37	1	the	the	DET
brj-23874	37	2	pulp	pulp	NOUN
brj-23874	37	3	of	of	ADP
brj-23874	37	4	c.	c.	PROPN
brj-23874	37	5	colocynthis	colocynthis	PROPN
brj-23874	37	6	fruit	fruit	NOUN
brj-23874	37	7	has	have	AUX
brj-23874	37	8	long	long	ADV
brj-23874	37	9	been	be	AUX
brj-23874	37	10	used	use	VERB
brj-23874	37	11	to	to	PART
brj-23874	37	12	treat	treat	VERB
brj-23874	37	13	digestive	digestive	ADJ
brj-23874	37	14	disorders	disorder	NOUN
brj-23874	37	15	,	,	PUNCT
brj-23874	37	16	such	such	ADJ
brj-23874	37	17	as	as	ADP
brj-23874	37	18	dyspepsia	dyspepsia	NOUN
brj-23874	37	19	,	,	PUNCT
brj-23874	37	20	and	and	CCONJ
brj-23874	37	21	parasite	parasite	NOUN
brj-23874	37	22	infections	infection	NOUN
brj-23874	37	23	.	.	PUNCT
brj-23874	38	1	the	the	DET
brj-23874	38	2	seed	seed	NOUN
brj-23874	38	3	powder	powder	NOUN
brj-23874	38	4	of	of	ADP
brj-23874	38	5	c.	c.	PROPN
brj-23874	38	6	colocynthis	colocynthis	PROPN
brj-23874	38	7	is	be	AUX
brj-23874	38	8	a	a	DET
brj-23874	38	9	versatile	versatile	ADJ
brj-23874	38	10	ingredient	ingredient	NOUN
brj-23874	38	11	with	with	ADP
brj-23874	38	12	medical	medical	ADJ
brj-23874	38	13	and	and	CCONJ
brj-23874	38	14	culinary	culinary	ADJ
brj-23874	38	15	applications	application	NOUN
brj-23874	38	16	(	(	PUNCT
brj-23874	38	17	li	li	X
brj-23874	38	18	et	et	PROPN
brj-23874	38	19	al	al	PROPN
brj-23874	38	20	2022	2022	NUM
brj-23874	38	21	)	)	PUNCT
brj-23874	38	22	.	.	PUNCT
brj-23874	39	1	its	its	PRON
brj-23874	39	2	antibacterial	antibacterial	ADJ
brj-23874	39	3	,	,	PUNCT
brj-23874	39	4	analgesic	analgesic	ADJ
brj-23874	39	5	,	,	PUNCT
brj-23874	39	6	anti	anti	ADJ
brj-23874	39	7	-	-	ADJ
brj-23874	39	8	inflammatory	inflammatory	ADJ
brj-23874	39	9	,	,	PUNCT
brj-23874	39	10	antioxidant	antioxidant	NOUN
brj-23874	39	11	,	,	PUNCT
brj-23874	39	12	and	and	CCONJ
brj-23874	39	13	fat	fat	ADJ
brj-23874	39	14	-	-	PUNCT
brj-23874	39	15	binding	bind	VERB
brj-23874	39	16	qualities	quality	NOUN
brj-23874	39	17	are	be	AUX
brj-23874	39	18	demonstrated	demonstrate	VERB
brj-23874	39	19	by	by	ADP
brj-23874	39	20	its	its	PRON
brj-23874	39	21	use	use	NOUN
brj-23874	39	22	as	as	ADP
brj-23874	39	23	an	an	DET
brj-23874	39	24	emulsifier	emulsifier	NOUN
brj-23874	39	25	,	,	PUNCT
brj-23874	39	26	flavoring	flavor	VERB
brj-23874	39	27	agent	agent	NOUN
brj-23874	39	28	,	,	PUNCT
brj-23874	39	29	and	and	CCONJ
brj-23874	39	30	fat	fat	ADJ
brj-23874	39	31	binder	binder	NOUN
brj-23874	39	32	(	(	PUNCT
brj-23874	39	33	kamran	kamran	PROPN
brj-23874	39	34	et	et	PROPN
brj-23874	39	35	al	al	PROPN
brj-23874	39	36	2018	2018	NUM
brj-23874	39	37	)	)	PUNCT
brj-23874	39	38	.	.	PUNCT
brj-23874	40	1	specifically	specifically	ADV
brj-23874	40	2	,	,	PUNCT
brj-23874	40	3	there	there	PRON
brj-23874	40	4	is	be	VERB
brj-23874	40	5	a	a	DET
brj-23874	40	6	lack	lack	NOUN
brj-23874	40	7	of	of	ADP
brj-23874	40	8	robust	robust	ADJ
brj-23874	40	9	evidence	evidence	NOUN
brj-23874	40	10	regarding	regard	VERB
brj-23874	40	11	its	its	PRON
brj-23874	40	12	mechanism	mechanism	NOUN
brj-23874	40	13	of	of	ADP
brj-23874	40	14	action	action	NOUN
brj-23874	40	15	in	in	ADP
brj-23874	40	16	alleviating	alleviate	VERB
brj-23874	40	17	pain	pain	NOUN
brj-23874	40	18	and	and	CCONJ
brj-23874	40	19	inflammation	inflammation	NOUN
brj-23874	40	20	and	and	CCONJ
brj-23874	40	21	its	its	PRON
brj-23874	40	22	comparative	comparative	ADJ
brj-23874	40	23	efficacy	efficacy	NOUN
brj-23874	40	24	against	against	ADP
brj-23874	40	25	standard	standard	ADJ
brj-23874	40	26	pharmaceutical	pharmaceutical	ADJ
brj-23874	40	27	agents	agent	NOUN
brj-23874	40	28	.	.	PUNCT
brj-23874	41	1	additionally	additionally	ADV
brj-23874	41	2	,	,	PUNCT
brj-23874	41	3	its	its	PRON
brj-23874	41	4	potential	potential	ADJ
brj-23874	41	5	applications	application	NOUN
brj-23874	41	6	in	in	ADP
brj-23874	41	7	specific	specific	ADJ
brj-23874	41	8	formulations	formulation	NOUN
brj-23874	41	9	or	or	CCONJ
brj-23874	41	10	delivery	delivery	NOUN
brj-23874	41	11	systems	system	NOUN
brj-23874	41	12	to	to	PART
brj-23874	41	13	enhance	enhance	VERB
brj-23874	41	14	bioavailability	bioavailability	NOUN
brj-23874	41	15	and	and	CCONJ
brj-23874	41	16	therapeutic	therapeutic	ADJ
brj-23874	41	17	effects	effect	NOUN
brj-23874	41	18	remain	remain	VERB
brj-23874	41	19	underexplored	underexplored	ADJ
brj-23874	41	20	.	.	PUNCT
brj-23874	42	1	for	for	ADP
brj-23874	42	2	the	the	DET
brj-23874	42	3	first	first	ADJ
brj-23874	42	4	time	time	NOUN
brj-23874	42	5	,	,	PUNCT
brj-23874	42	6	this	this	DET
brj-23874	42	7	study	study	NOUN
brj-23874	42	8	investigates	investigate	VERB
brj-23874	42	9	the	the	DET
brj-23874	42	10	pharmacological	pharmacological	ADJ
brj-23874	42	11	efficacy	efficacy	NOUN
brj-23874	42	12	of	of	ADP
brj-23874	42	13	c.	c.	PROPN
brj-23874	42	14	colocynthis	colocynthis	PROPN
brj-23874	42	15	using	use	VERB
brj-23874	42	16	advanced	advanced	ADJ
brj-23874	42	17	in	in	ADP
brj-23874	42	18	vivo	vivo	ADJ
brj-23874	42	19	experimental	experimental	ADJ
brj-23874	42	20	models	model	NOUN
brj-23874	42	21	,	,	PUNCT
brj-23874	42	22	including	include	VERB
brj-23874	42	23	the	the	DET
brj-23874	42	24	hot	hot	ADJ
brj-23874	42	25	plate	plate	NOUN
brj-23874	42	26	test	test	NOUN
brj-23874	42	27	and	and	CCONJ
brj-23874	42	28	the	the	DET
brj-23874	42	29	carrageenan	carrageenan	NOUN
brj-23874	42	30	-	-	PUNCT
brj-23874	42	31	induced	induce	VERB
brj-23874	42	32	rat	rat	NOUN
brj-23874	42	33	paw	paw	PROPN
brj-23874	42	34	edema	edema	NOUN
brj-23874	42	35	assay	assay	VERB
brj-23874	42	36	.	.	PUNCT
brj-23874	43	1	the	the	DET
brj-23874	43	2	study	study	NOUN
brj-23874	43	3	provides	provide	VERB
brj-23874	43	4	detailed	detailed	ADJ
brj-23874	43	5	insights	insight	NOUN
brj-23874	43	6	into	into	ADP
brj-23874	43	7	the	the	DET
brj-23874	43	8	plant	plant	NOUN
brj-23874	43	9	’s	’s	PART
brj-23874	43	10	mechanism	mechanism	NOUN
brj-23874	43	11	of	of	ADP
brj-23874	43	12	action	action	NOUN
brj-23874	43	13	,	,	PUNCT
brj-23874	43	14	focusing	focus	VERB
brj-23874	43	15	on	on	ADP
brj-23874	43	16	its	its	PRON
brj-23874	43	17	analgesic	analgesic	ADJ
brj-23874	43	18	and	and	CCONJ
brj-23874	43	19	anti	anti	ADJ
brj-23874	43	20	-	-	ADJ
brj-23874	43	21	inflammatory	inflammatory	ADJ
brj-23874	43	22	effects	effect	NOUN
brj-23874	43	23	.	.	PUNCT
brj-23874	44	1	furthermore	furthermore	ADV
brj-23874	44	2	,	,	PUNCT
brj-23874	44	3	the	the	DET
brj-23874	44	4	study	study	NOUN
brj-23874	44	5	explores	explore	VERB
brj-23874	44	6	antibacterial	antibacterial	ADJ
brj-23874	44	7	properties	property	NOUN
brj-23874	44	8	highlighting	highlight	VERB
brj-23874	44	9	their	their	PRON
brj-23874	44	10	potential	potential	NOUN
brj-23874	44	11	for	for	ADP
brj-23874	44	12	medical	medical	ADJ
brj-23874	44	13	and	and	CCONJ
brj-23874	44	14	culinary	culinary	ADJ
brj-23874	44	15	applications	application	NOUN
brj-23874	44	16	.	.	PUNCT
brj-23874	45	1	these	these	DET
brj-23874	45	2	findings	finding	NOUN
brj-23874	45	3	represent	represent	VERB
brj-23874	45	4	a	a	DET
brj-23874	45	5	novel	novel	ADJ
brj-23874	45	6	contribution	contribution	NOUN
brj-23874	45	7	to	to	ADP
brj-23874	45	8	understanding	understand	VERB
brj-23874	45	9	the	the	DET
brj-23874	45	10	therapeutic	therapeutic	ADJ
brj-23874	45	11	potential	potential	NOUN
brj-23874	45	12	of	of	ADP
brj-23874	45	13	c.	c.	PROPN
brj-23874	45	14	colocynthis	colocynthis	PROPN
brj-23874	45	15	and	and	CCONJ
brj-23874	45	16	its	its	PRON
brj-23874	45	17	practical	practical	ADJ
brj-23874	45	18	applications	application	NOUN
brj-23874	45	19	experimental	experimental	ADJ
brj-23874	45	20	materials	material	NOUN
brj-23874	45	21	foetal	foetal	ADJ
brj-23874	45	22	bovine	bovine	NOUN
brj-23874	45	23	serum	serum	NOUN
brj-23874	45	24	(	(	PUNCT
brj-23874	45	25	fbs	fbs	PROPN
brj-23874	45	26	)	)	PUNCT
brj-23874	45	27	,	,	PUNCT
brj-23874	45	28	sodium	sodium	NOUN
brj-23874	45	29	pyruvate	pyruvate	NOUN
brj-23874	45	30	,	,	PUNCT
brj-23874	45	31	glutamine	glutamine	NOUN
brj-23874	45	32	,	,	PUNCT
brj-23874	45	33	and	and	CCONJ
brj-23874	45	34	dimethyl	dimethyl	NOUN
brj-23874	45	35	sulfoxide	sulfoxide	NOUN
brj-23874	45	36	(	(	PUNCT
brj-23874	45	37	dmso	dmso	NOUN
brj-23874	45	38	)	)	PUNCT
brj-23874	45	39	was	be	AUX
brj-23874	45	40	sourced	source	VERB
brj-23874	45	41	from	from	ADP
brj-23874	45	42	sigma	sigma	PROPN
brj-23874	45	43	aldrich	aldrich	PROPN
brj-23874	45	44	,	,	PUNCT
brj-23874	45	45	based	base	VERB
brj-23874	45	46	in	in	ADP
brj-23874	45	47	shanghai	shanghai	PROPN
brj-23874	45	48	.	.	PUNCT
brj-23874	46	1	preparation	preparation	NOUN
brj-23874	46	2	of	of	ADP
brj-23874	46	3	plant	plant	NOUN
brj-23874	46	4	extract	extract	NOUN
brj-23874	46	5	c.	c.	PROPN
brj-23874	46	6	colocynthis	colocynthis	PROPN
brj-23874	46	7	fruits	fruit	NOUN
brj-23874	46	8	were	be	AUX
brj-23874	46	9	crushed	crush	VERB
brj-23874	46	10	to	to	PART
brj-23874	46	11	obtain	obtain	VERB
brj-23874	46	12	seeds	seed	NOUN
brj-23874	46	13	for	for	ADP
brj-23874	46	14	this	this	DET
brj-23874	46	15	study	study	NOUN
brj-23874	46	16	.	.	PUNCT
brj-23874	47	1	approximately	approximately	ADV
brj-23874	47	2	5	5	NUM
brj-23874	47	3	g	g	NOUN
brj-23874	47	4	of	of	ADP
brj-23874	47	5	seeds	seed	NOUN
brj-23874	47	6	were	be	AUX
brj-23874	47	7	finely	finely	ADV
brj-23874	47	8	ground	grind	VERB
brj-23874	47	9	into	into	ADP
brj-23874	47	10	a	a	DET
brj-23874	47	11	powder	powder	NOUN
brj-23874	47	12	and	and	CCONJ
brj-23874	47	13	mixed	mix	VERB
brj-23874	47	14	with	with	ADP
brj-23874	47	15	100	100	NUM
brj-23874	47	16	ml	ml	NOUN
brj-23874	47	17	of	of	ADP
brj-23874	47	18	distilled	distil	VERB
brj-23874	47	19	water	water	NOUN
brj-23874	47	20	.	.	PUNCT
brj-23874	48	1	the	the	DET
brj-23874	48	2	mixture	mixture	NOUN
brj-23874	48	3	was	be	AUX
brj-23874	48	4	then	then	ADV
brj-23874	48	5	heated	heated	ADJ
brj-23874	48	6	to	to	ADP
brj-23874	48	7	a	a	DET
brj-23874	48	8	boil	boil	NOUN
brj-23874	48	9	and	and	CCONJ
brj-23874	48	10	allowed	allow	VERB
brj-23874	48	11	to	to	PART
brj-23874	48	12	simmer	simmer	VERB
brj-23874	48	13	for	for	ADP
brj-23874	48	14	10	10	NUM
brj-23874	48	15	to	to	PART
brj-23874	48	16	15	15	NUM
brj-23874	48	17	min	min	NOUN
brj-23874	48	18	.	.	PROPN
brj-23874	49	1	then	then	ADV
brj-23874	49	2	it	it	PRON
brj-23874	49	3	was	be	AUX
brj-23874	49	4	set	set	VERB
brj-23874	49	5	peer	peer	NOUN
brj-23874	49	6	-	-	PUNCT
brj-23874	49	7	reviewed	review	VERB
brj-23874	49	8	article	article	NOUN
brj-23874	49	9	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	49	10	zhu	zhu	PROPN
brj-23874	49	11	et	et	PROPN
brj-23874	49	12	al	al	PROPN
brj-23874	49	13	.	.	PROPN
brj-23874	50	1	(	(	PUNCT
brj-23874	50	2	2026	2026	NUM
brj-23874	50	3	)	)	PUNCT
brj-23874	50	4	.	.	PUNCT
brj-23874	51	1	“	"	PUNCT
brj-23874	51	2	pain	pain	NOUN
brj-23874	51	3	control	control	NOUN
brj-23874	51	4	with	with	ADP
brj-23874	51	5	seed	seed	NOUN
brj-23874	51	6	extract	extract	NOUN
brj-23874	51	7	,	,	PUNCT
brj-23874	51	8	”	"	PUNCT
brj-23874	51	9	bioresources	bioresource	NOUN
brj-23874	51	10	21(1	21(1	NUM
brj-23874	51	11	)	)	PUNCT
brj-23874	51	12	,	,	PUNCT
brj-23874	51	13	116	116	NUM
brj-23874	51	14	-	-	SYM
brj-23874	51	15	127	127	NUM
brj-23874	51	16	.	.	PUNCT
brj-23874	52	1	118	118	NUM
brj-23874	52	2	aside	aside	ADV
brj-23874	52	3	for	for	ADP
brj-23874	52	4	2	2	NUM
brj-23874	52	5	h.	h.	NOUN
brj-23874	52	6	subsequently	subsequently	ADV
brj-23874	52	7	,	,	PUNCT
brj-23874	52	8	the	the	DET
brj-23874	52	9	purified	purified	ADJ
brj-23874	52	10	extract	extract	NOUN
brj-23874	52	11	was	be	AUX
brj-23874	52	12	separated	separate	VERB
brj-23874	52	13	from	from	ADP
brj-23874	52	14	the	the	DET
brj-23874	52	15	larger	large	ADJ
brj-23874	52	16	particles	particle	NOUN
brj-23874	52	17	using	use	VERB
brj-23874	52	18	a	a	DET
brj-23874	52	19	process	process	NOUN
brj-23874	52	20	of	of	ADP
brj-23874	52	21	triple	triple	ADJ
brj-23874	52	22	filtration	filtration	NOUN
brj-23874	52	23	.	.	PUNCT
brj-23874	53	1	cytotoxicity	cytotoxicity	NOUN
brj-23874	53	2	studies	study	NOUN
brj-23874	53	3	cell	cell	NOUN
brj-23874	53	4	culture	culture	NOUN
brj-23874	53	5	a	a	DET
brj-23874	53	6	75	75	NUM
brj-23874	53	7	-	-	PUNCT
brj-23874	53	8	cm²	cm²	NOUN
brj-23874	53	9	flask	flask	NOUN
brj-23874	53	10	containing	contain	VERB
brj-23874	53	11	10	10	NUM
brj-23874	53	12	%	%	NOUN
brj-23874	53	13	fbs	fb	VERB
brj-23874	53	14	,	,	PUNCT
brj-23874	53	15	1	1	NUM
brj-23874	53	16	mm	mm	NUM
brj-23874	53	17	sodium	sodium	NOUN
brj-23874	53	18	pyruvate	pyruvate	NOUN
brj-23874	53	19	,	,	PUNCT
brj-23874	53	20	1	1	NUM
brj-23874	53	21	%	%	NOUN
brj-23874	53	22	non	non	ADJ
brj-23874	53	23	-	-	ADJ
brj-23874	53	24	essential	essential	ADJ
brj-23874	53	25	amino	amino	NOUN
brj-23874	53	26	acids	acid	NOUN
brj-23874	53	27	,	,	PUNCT
brj-23874	53	28	2	2	NUM
brj-23874	53	29	mm	mm	NOUN
brj-23874	53	30	l	l	NOUN
brj-23874	53	31	-	-	NOUN
brj-23874	53	32	glutamine	glutamine	NOUN
brj-23874	53	33	,	,	PUNCT
brj-23874	53	34	and	and	CCONJ
brj-23874	53	35	antibiotics	antibiotic	NOUN
brj-23874	53	36	was	be	AUX
brj-23874	53	37	used	use	VERB
brj-23874	53	38	to	to	PART
brj-23874	53	39	cultivate	cultivate	VERB
brj-23874	53	40	the	the	DET
brj-23874	53	41	b16f10	b16f10	ADJ
brj-23874	53	42	mouse	mouse	NOUN
brj-23874	53	43	melanoma	melanoma	NOUN
brj-23874	53	44	cells	cell	NOUN
brj-23874	53	45	.	.	PUNCT
brj-23874	54	1	the	the	DET
brj-23874	54	2	temperature	temperature	NOUN
brj-23874	54	3	of	of	ADP
brj-23874	54	4	these	these	DET
brj-23874	54	5	cultures	culture	NOUN
brj-23874	54	6	was	be	AUX
brj-23874	54	7	kept	keep	VERB
brj-23874	54	8	at	at	ADP
brj-23874	54	9	37	37	NUM
brj-23874	54	10	°	°	NOUN
brj-23874	54	11	c	c	NOUN
brj-23874	54	12	in	in	ADP
brj-23874	54	13	an	an	DET
brj-23874	54	14	environment	environment	NOUN
brj-23874	54	15	with	with	ADP
brj-23874	54	16	5	5	NUM
brj-23874	54	17	%	%	NOUN
brj-23874	54	18	co2	co2	NOUN
brj-23874	54	19	.	.	PUNCT
brj-23874	55	1	mtt	mtt	PROPN
brj-23874	55	2	assay	assay	VERB
brj-23874	55	3	an	an	DET
brj-23874	55	4	mtt	mtt	NOUN
brj-23874	55	5	assay	assay	NOUN
brj-23874	55	6	was	be	AUX
brj-23874	55	7	used	use	VERB
brj-23874	55	8	to	to	PART
brj-23874	55	9	evaluate	evaluate	VERB
brj-23874	55	10	the	the	DET
brj-23874	55	11	effect	effect	NOUN
brj-23874	55	12	of	of	ADP
brj-23874	55	13	c.	c.	NOUN
brj-23874	55	14	colocynthis	colocynthis	PROPN
brj-23874	55	15	extracts	extract	NOUN
brj-23874	55	16	on	on	ADP
brj-23874	55	17	b16f10	b16f10	ADJ
brj-23874	55	18	melanoma	melanoma	NOUN
brj-23874	55	19	cells	cell	NOUN
brj-23874	55	20	.	.	PUNCT
brj-23874	56	1	to	to	PART
brj-23874	56	2	perform	perform	VERB
brj-23874	56	3	the	the	DET
brj-23874	56	4	experiment	experiment	NOUN
brj-23874	56	5	,	,	PUNCT
brj-23874	56	6	100	100	NUM
brj-23874	56	7	µl	µl	NOUN
brj-23874	56	8	of	of	ADP
brj-23874	56	9	growth	growth	NOUN
brj-23874	56	10	media	medium	NOUN
brj-23874	56	11	each	each	PRON
brj-23874	56	12	well	well	ADV
brj-23874	56	13	in	in	ADP
brj-23874	56	14	a	a	DET
brj-23874	56	15	96well	96well	NUM
brj-23874	56	16	plate	plate	NOUN
brj-23874	56	17	was	be	AUX
brj-23874	56	18	used	use	VERB
brj-23874	56	19	to	to	PART
brj-23874	56	20	plate	plate	VERB
brj-23874	56	21	3	3	NUM
brj-23874	56	22	×	×	NOUN
brj-23874	56	23	103	103	NUM
brj-23874	56	24	cells	cell	NOUN
brj-23874	56	25	/	/	SYM
brj-23874	56	26	ml	ml	NOUN
brj-23874	56	27	and	and	CCONJ
brj-23874	56	28	incubated	incubate	VERB
brj-23874	56	29	at	at	ADP
brj-23874	56	30	37	37	NUM
brj-23874	56	31	°	°	NOUN
brj-23874	56	32	c	c	NOUN
brj-23874	56	33	for	for	ADP
brj-23874	56	34	48	48	NUM
brj-23874	56	35	h.	h.	NOUN
brj-23874	56	36	after	after	ADP
brj-23874	56	37	incubation	incubation	NOUN
brj-23874	56	38	,	,	PUNCT
brj-23874	56	39	cells	cell	NOUN
brj-23874	56	40	were	be	AUX
brj-23874	56	41	added	add	VERB
brj-23874	56	42	with	with	ADP
brj-23874	56	43	different	different	ADJ
brj-23874	56	44	doses	dose	NOUN
brj-23874	56	45	of	of	ADP
brj-23874	56	46	the	the	DET
brj-23874	56	47	extract	extract	NOUN
brj-23874	56	48	(	(	PUNCT
brj-23874	56	49	25	25	NUM
brj-23874	56	50	to	to	PART
brj-23874	56	51	150	150	NUM
brj-23874	56	52	µg	µg	NOUN
brj-23874	56	53	/	/	SYM
brj-23874	56	54	ml	ml	NOUN
brj-23874	56	55	)	)	PUNCT
brj-23874	56	56	and	and	CCONJ
brj-23874	56	57	allowed	allow	VERB
brj-23874	56	58	to	to	PART
brj-23874	56	59	incubate	incubate	VERB
brj-23874	56	60	for	for	ADP
brj-23874	56	61	a	a	DET
brj-23874	56	62	further	further	ADJ
brj-23874	56	63	24	24	NUM
brj-23874	56	64	h	h	NOUN
brj-23874	56	65	at	at	ADP
brj-23874	56	66	37	37	NUM
brj-23874	56	67	°	°	NOUN
brj-23874	56	68	c	c	NOUN
brj-23874	56	69	.	.	PUNCT
brj-23874	57	1	each	each	DET
brj-23874	57	2	well	well	ADV
brj-23874	57	3	was	be	AUX
brj-23874	57	4	filled	fill	VERB
brj-23874	57	5	with	with	ADP
brj-23874	57	6	8	8	NUM
brj-23874	57	7	µl	µl	NOUN
brj-23874	57	8	of	of	ADP
brj-23874	57	9	mtt	mtt	NOUN
brj-23874	57	10	solution	solution	NOUN
brj-23874	57	11	and	and	CCONJ
brj-23874	57	12	incubated	incubate	VERB
brj-23874	57	13	at	at	ADP
brj-23874	57	14	37	37	NUM
brj-23874	57	15	°	°	ADP
brj-23874	57	16	c	c	NOUN
brj-23874	57	17	for	for	ADP
brj-23874	57	18	4	4	NUM
brj-23874	57	19	h.	h.	NOUN
brj-23874	57	20	after	after	ADP
brj-23874	57	21	solubilizing	solubilize	VERB
brj-23874	57	22	the	the	DET
brj-23874	57	23	cells	cell	NOUN
brj-23874	57	24	with	with	ADP
brj-23874	57	25	100	100	NUM
brj-23874	57	26	µl	µl	NOUN
brj-23874	57	27	of	of	ADP
brj-23874	57	28	dimethyl	dimethyl	NOUN
brj-23874	57	29	sulfoxide	sulfoxide	NOUN
brj-23874	57	30	(	(	PUNCT
brj-23874	57	31	dmso	dmso	NOUN
brj-23874	57	32	)	)	PUNCT
brj-23874	57	33	,	,	PUNCT
brj-23874	57	34	absorbance	absorbance	NOUN
brj-23874	57	35	was	be	AUX
brj-23874	57	36	measured	measure	VERB
brj-23874	57	37	at	at	ADP
brj-23874	57	38	570	570	NUM
brj-23874	57	39	nm	nm	NOUN
brj-23874	57	40	using	use	VERB
brj-23874	57	41	an	an	DET
brj-23874	57	42	automated	automate	VERB
brj-23874	57	43	microplate	microplate	NOUN
brj-23874	57	44	reader	reader	NOUN
brj-23874	57	45	.	.	PUNCT
brj-23874	58	1	there	there	PRON
brj-23874	58	2	was	be	VERB
brj-23874	58	3	a	a	DET
brj-23874	58	4	direct	direct	ADJ
brj-23874	58	5	correlation	correlation	NOUN
brj-23874	58	6	between	between	ADP
brj-23874	58	7	the	the	DET
brj-23874	58	8	absorbance	absorbance	NOUN
brj-23874	58	9	level	level	NOUN
brj-23874	58	10	and	and	CCONJ
brj-23874	58	11	the	the	DET
brj-23874	58	12	quantity	quantity	NOUN
brj-23874	58	13	of	of	ADP
brj-23874	58	14	viable	viable	ADJ
brj-23874	58	15	cells	cell	NOUN
brj-23874	58	16	.	.	PUNCT
brj-23874	59	1	live	live	VERB
brj-23874	59	2	and	and	CCONJ
brj-23874	59	3	dead	dead	ADJ
brj-23874	59	4	cell	cell	NOUN
brj-23874	59	5	assay	assay	VERB
brj-23874	59	6	by	by	ADP
brj-23874	59	7	confocal	confocal	ADJ
brj-23874	59	8	laser	laser	NOUN
brj-23874	59	9	scanning	scan	VERB
brj-23874	59	10	microscopy	microscopy	NOUN
brj-23874	59	11	(	(	PUNCT
brj-23874	59	12	clsm	clsm	X
brj-23874	59	13	)	)	PUNCT
brj-23874	59	14	using	use	VERB
brj-23874	59	15	fluorescein	fluorescein	NOUN
brj-23874	59	16	diacetate	diacetate	NOUN
brj-23874	59	17	and	and	CCONJ
brj-23874	59	18	propidium	propidium	NOUN
brj-23874	59	19	iodide	iodide	NOUN
brj-23874	59	20	staining	stain	VERB
brj-23874	59	21	the	the	DET
brj-23874	59	22	viability	viability	NOUN
brj-23874	59	23	of	of	ADP
brj-23874	59	24	the	the	DET
brj-23874	59	25	cells	cell	NOUN
brj-23874	59	26	was	be	AUX
brj-23874	59	27	evaluated	evaluate	VERB
brj-23874	59	28	qualitatively	qualitatively	ADV
brj-23874	59	29	using	use	VERB
brj-23874	59	30	confocal	confocal	ADJ
brj-23874	59	31	microscopy	microscopy	NOUN
brj-23874	59	32	following	follow	VERB
brj-23874	59	33	labelling	label	VERB
brj-23874	59	34	with	with	ADP
brj-23874	59	35	propidium	propidium	NOUN
brj-23874	59	36	iodide	iodide	NOUN
brj-23874	59	37	(	(	PUNCT
brj-23874	59	38	pi	pi	NOUN
brj-23874	59	39	)	)	PUNCT
brj-23874	59	40	and	and	CCONJ
brj-23874	59	41	fluorescein	fluorescein	ADJ
brj-23874	59	42	diacetate	diacetate	NOUN
brj-23874	59	43	(	(	PUNCT
brj-23874	59	44	fd	fd	PROPN
brj-23874	59	45	)	)	PUNCT
brj-23874	59	46	.	.	PUNCT
brj-23874	60	1	trypsinization	trypsinization	NOUN
brj-23874	60	2	was	be	AUX
brj-23874	60	3	followed	follow	VERB
brj-23874	60	4	by	by	ADP
brj-23874	60	5	resuspension	resuspension	NOUN
brj-23874	60	6	of	of	ADP
brj-23874	60	7	the	the	DET
brj-23874	60	8	cells	cell	NOUN
brj-23874	60	9	in	in	ADP
brj-23874	60	10	complete	complete	ADJ
brj-23874	60	11	culture	culture	NOUN
brj-23874	60	12	medium	medium	NOUN
brj-23874	60	13	at	at	ADP
brj-23874	60	14	a	a	DET
brj-23874	60	15	density	density	NOUN
brj-23874	60	16	of	of	ADP
brj-23874	60	17	10	10	NUM
brj-23874	60	18	×	×	NOUN
brj-23874	60	19	104	104	NUM
brj-23874	60	20	cells	cell	NOUN
brj-23874	60	21	/	/	SYM
brj-23874	60	22	ml	ml	NOUN
brj-23874	60	23	.	.	PUNCT
brj-23874	61	1	after	after	ADP
brj-23874	61	2	that	that	PRON
brj-23874	61	3	,	,	PUNCT
brj-23874	61	4	a	a	DET
brj-23874	61	5	2	2	NUM
brj-23874	61	6	ml	ml	NOUN
brj-23874	61	7	aliquot	aliquot	NOUN
brj-23874	61	8	of	of	ADP
brj-23874	61	9	the	the	DET
brj-23874	61	10	cell	cell	NOUN
brj-23874	61	11	suspension	suspension	NOUN
brj-23874	61	12	was	be	AUX
brj-23874	61	13	put	put	VERB
brj-23874	61	14	on	on	ADP
brj-23874	61	15	a	a	DET
brj-23874	61	16	cell	cell	NOUN
brj-23874	61	17	culture	culture	NOUN
brj-23874	61	18	dish	dish	NOUN
brj-23874	61	19	and	and	CCONJ
brj-23874	61	20	left	leave	VERB
brj-23874	61	21	there	there	ADV
brj-23874	61	22	for	for	ADP
brj-23874	61	23	the	the	DET
brj-23874	61	24	entire	entire	ADJ
brj-23874	61	25	night	night	NOUN
brj-23874	61	26	at	at	ADP
brj-23874	61	27	37	37	NUM
brj-23874	61	28	°	°	NOUN
brj-23874	61	29	c	c	NOUN
brj-23874	61	30	with	with	ADP
brj-23874	61	31	5	5	NUM
brj-23874	61	32	%	%	NOUN
brj-23874	61	33	co2	co2	NOUN
brj-23874	61	34	.	.	PUNCT
brj-23874	62	1	the	the	DET
brj-23874	62	2	following	following	ADJ
brj-23874	62	3	day	day	NOUN
brj-23874	62	4	,	,	PUNCT
brj-23874	62	5	the	the	DET
brj-23874	62	6	culture	culture	NOUN
brj-23874	62	7	media	medium	NOUN
brj-23874	62	8	was	be	AUX
brj-23874	62	9	taken	take	VERB
brj-23874	62	10	out	out	ADP
brj-23874	62	11	and	and	CCONJ
brj-23874	62	12	replaced	replace	VERB
brj-23874	62	13	with	with	ADP
brj-23874	62	14	100	100	NUM
brj-23874	62	15	µg	µg	NOUN
brj-23874	62	16	/	/	SYM
brj-23874	62	17	ml	ml	NOUN
brj-23874	62	18	of	of	ADP
brj-23874	62	19	plant	plant	NOUN
brj-23874	62	20	extract	extract	NOUN
brj-23874	62	21	.	.	PUNCT
brj-23874	63	1	after	after	SCONJ
brj-23874	63	2	the	the	DET
brj-23874	63	3	media	medium	NOUN
brj-23874	63	4	were	be	AUX
brj-23874	63	5	evacuated	evacuate	VERB
brj-23874	63	6	after	after	ADP
brj-23874	63	7	a	a	DET
brj-23874	63	8	24	24	NUM
brj-23874	63	9	h	h	NOUN
brj-23874	63	10	incubation	incubation	NOUN
brj-23874	63	11	,	,	PUNCT
brj-23874	63	12	600	600	NUM
brj-23874	63	13	µl	µl	NOUN
brj-23874	63	14	of	of	ADP
brj-23874	63	15	fd	fd	PROPN
brj-23874	63	16	(	(	PUNCT
brj-23874	63	17	10	10	NUM
brj-23874	63	18	µg	µg	NOUN
brj-23874	63	19	/	/	SYM
brj-23874	63	20	ml	ml	NOUN
brj-23874	63	21	in	in	ADP
brj-23874	63	22	0.2	0.2	NUM
brj-23874	63	23	%	%	NOUN
brj-23874	63	24	dmso	dmso	NOUN
brj-23874	63	25	/	/	SYM
brj-23874	63	26	pbs	pbs	PROPN
brj-23874	63	27	)	)	PUNCT
brj-23874	63	28	and	and	CCONJ
brj-23874	63	29	600	600	NUM
brj-23874	63	30	µl	µl	NOUN
brj-23874	63	31	of	of	ADP
brj-23874	63	32	pi	pi	NOUN
brj-23874	63	33	(	(	PUNCT
brj-23874	63	34	5	5	NUM
brj-23874	63	35	µg	µg	ADV
brj-23874	63	36	/	/	SYM
brj-23874	63	37	ml	ml	NOUN
brj-23874	63	38	in	in	ADP
brj-23874	63	39	pbs	pbs	PROPN
brj-23874	63	40	)	)	PUNCT
brj-23874	63	41	were	be	AUX
brj-23874	63	42	added	add	VERB
brj-23874	63	43	to	to	ADP
brj-23874	63	44	the	the	DET
brj-23874	63	45	cells	cell	NOUN
brj-23874	63	46	.	.	PUNCT
brj-23874	64	1	after	after	ADP
brj-23874	64	2	gently	gently	ADV
brj-23874	64	3	mixing	mix	VERB
brj-23874	64	4	the	the	DET
brj-23874	64	5	cells	cell	NOUN
brj-23874	64	6	,	,	PUNCT
brj-23874	64	7	they	they	PRON
brj-23874	64	8	were	be	AUX
brj-23874	64	9	incubated	incubate	VERB
brj-23874	64	10	for	for	ADP
brj-23874	64	11	10	10	NUM
brj-23874	64	12	min	min	NOUN
brj-23874	64	13	in	in	ADP
brj-23874	64	14	the	the	DET
brj-23874	64	15	dark	dark	NOUN
brj-23874	64	16	.	.	PUNCT
brj-23874	65	1	the	the	DET
brj-23874	65	2	cells	cell	NOUN
brj-23874	65	3	were	be	AUX
brj-23874	65	4	then	then	ADV
brj-23874	65	5	twice	twice	ADV
brj-23874	65	6	washed	wash	VERB
brj-23874	65	7	with	with	ADP
brj-23874	65	8	1	1	NUM
brj-23874	65	9	ml	ml	NOUN
brj-23874	65	10	of	of	ADP
brj-23874	65	11	pbs	pbs	PROPN
brj-23874	65	12	,	,	PUNCT
brj-23874	65	13	and	and	CCONJ
brj-23874	65	14	each	each	DET
brj-23874	65	15	plate	plate	NOUN
brj-23874	65	16	was	be	AUX
brj-23874	65	17	filled	fill	VERB
brj-23874	65	18	with	with	ADP
brj-23874	65	19	1	1	NUM
brj-23874	65	20	ml	ml	NOUN
brj-23874	65	21	of	of	ADP
brj-23874	65	22	imaging	imaging	NOUN
brj-23874	65	23	media	medium	NOUN
brj-23874	65	24	before	before	ADP
brj-23874	65	25	being	be	AUX
brj-23874	65	26	imaged	image	VERB
brj-23874	65	27	using	use	VERB
brj-23874	65	28	clsm	clsm	NOUN
brj-23874	65	29	.	.	PUNCT
brj-23874	66	1	anti	anti	ADJ
brj-23874	66	2	-	-	ADJ
brj-23874	66	3	microbial	microbial	ADJ
brj-23874	66	4	assay	assay	VERB
brj-23874	66	5	the	the	DET
brj-23874	66	6	gram	gram	NOUN
brj-23874	66	7	-	-	PUNCT
brj-23874	66	8	negative	negative	ADJ
brj-23874	66	9	microorganisms	microorganism	NOUN
brj-23874	66	10	escherichia	escherichia	NOUN
brj-23874	66	11	coli	coli	NOUN
brj-23874	66	12	(	(	PUNCT
brj-23874	66	13	e.	e.	NOUN
brj-23874	66	14	coli	coli	PROPN
brj-23874	66	15	)	)	PUNCT
brj-23874	66	16	and	and	CCONJ
brj-23874	66	17	pseudomonas	pseudomona	NOUN
brj-23874	66	18	aeruginosa	aeruginosa	NOUN
brj-23874	66	19	(	(	PUNCT
brj-23874	66	20	p.	p.	NOUN
brj-23874	66	21	aeruginosa	aeruginosa	PROPN
brj-23874	66	22	)	)	PUNCT
brj-23874	66	23	and	and	CCONJ
brj-23874	66	24	the	the	DET
brj-23874	66	25	gram	gram	NOUN
brj-23874	66	26	-	-	PUNCT
brj-23874	66	27	positive	positive	ADJ
brj-23874	66	28	organisms	organism	NOUN
brj-23874	66	29	staphylococcus	staphylococcus	NOUN
brj-23874	66	30	aureus	aureus	PROPN
brj-23874	66	31	(	(	PUNCT
brj-23874	66	32	s.	s.	PROPN
brj-23874	66	33	aureus	aureus	PROPN
brj-23874	66	34	)	)	PUNCT
brj-23874	66	35	and	and	CCONJ
brj-23874	66	36	enterococcus	enterococcus	NOUN
brj-23874	66	37	faecalis	faecalis	NOUN
brj-23874	66	38	(	(	PUNCT
brj-23874	66	39	e.	e.	PROPN
brj-23874	66	40	faecalis	faecalis	PROPN
brj-23874	66	41	)	)	PUNCT
brj-23874	66	42	were	be	AUX
brj-23874	66	43	used	use	VERB
brj-23874	66	44	to	to	PART
brj-23874	66	45	test	test	VERB
brj-23874	66	46	the	the	DET
brj-23874	66	47	extract	extract	NOUN
brj-23874	66	48	’s	’s	PART
brj-23874	66	49	antibacterial	antibacterial	ADJ
brj-23874	66	50	activity	activity	NOUN
brj-23874	66	51	.	.	PUNCT
brj-23874	67	1	individual	individual	ADJ
brj-23874	67	2	colonies	colony	NOUN
brj-23874	67	3	from	from	ADP
brj-23874	67	4	a	a	DET
brj-23874	67	5	24	24	NUM
brj-23874	67	6	h	h	NOUN
brj-23874	67	7	culture	culture	NOUN
brj-23874	67	8	were	be	AUX
brj-23874	67	9	suspended	suspend	VERB
brj-23874	67	10	in	in	ADP
brj-23874	67	11	a	a	DET
brj-23874	67	12	saline	saline	ADJ
brj-23874	67	13	solution	solution	NOUN
brj-23874	67	14	on	on	ADP
brj-23874	67	15	agar	agar	NOUN
brj-23874	67	16	plates	plate	NOUN
brj-23874	67	17	.	.	PUNCT
brj-23874	68	1	disc	disc	NOUN
brj-23874	68	2	diffusion	diffusion	NOUN
brj-23874	68	3	technique	technique	NOUN
brj-23874	68	4	was	be	AUX
brj-23874	68	5	used	use	VERB
brj-23874	68	6	to	to	PART
brj-23874	68	7	evaluate	evaluate	VERB
brj-23874	68	8	antimicrobial	antimicrobial	ADJ
brj-23874	68	9	potential	potential	NOUN
brj-23874	68	10	of	of	ADP
brj-23874	68	11	the	the	DET
brj-23874	68	12	extracts	extract	NOUN
brj-23874	68	13	.	.	PUNCT
brj-23874	69	1	suspensions	suspension	NOUN
brj-23874	69	2	were	be	AUX
brj-23874	69	3	evenly	evenly	ADV
brj-23874	69	4	distributed	distribute	VERB
brj-23874	69	5	across	across	ADP
brj-23874	69	6	mueller	mueller	PROPN
brj-23874	69	7	-	-	PUNCT
brj-23874	69	8	hinton	hinton	PROPN
brj-23874	69	9	agar	agar	NOUN
brj-23874	69	10	(	(	PUNCT
brj-23874	69	11	mha	mha	NOUN
brj-23874	69	12	)	)	PUNCT
brj-23874	69	13	plates	plate	NOUN
brj-23874	69	14	,	,	PUNCT
brj-23874	69	15	each	each	PRON
brj-23874	69	16	holding	hold	VERB
brj-23874	69	17	25	25	NUM
brj-23874	69	18	ml	ml	NOUN
brj-23874	69	19	of	of	ADP
brj-23874	69	20	the	the	DET
brj-23874	69	21	medium	medium	NOUN
brj-23874	69	22	,	,	PUNCT
brj-23874	69	23	for	for	ADP
brj-23874	69	24	every	every	DET
brj-23874	69	25	bacterial	bacterial	ADJ
brj-23874	69	26	strain	strain	NOUN
brj-23874	69	27	.	.	PUNCT
brj-23874	70	1	approximately	approximately	ADV
brj-23874	70	2	5	5	NUM
brj-23874	70	3	mg	mg	NOUN
brj-23874	70	4	of	of	ADP
brj-23874	70	5	dry	dry	ADJ
brj-23874	70	6	extracts	extract	NOUN
brj-23874	70	7	were	be	AUX
brj-23874	70	8	added	add	VERB
brj-23874	70	9	to	to	ADP
brj-23874	70	10	each	each	PRON
brj-23874	70	11	of	of	ADP
brj-23874	70	12	the	the	DET
brj-23874	70	13	individual	individual	ADJ
brj-23874	70	14	discs	disc	NOUN
brj-23874	70	15	,	,	PUNCT
brj-23874	70	16	with	with	ADP
brj-23874	70	17	a	a	DET
brj-23874	70	18	control	control	NOUN
brj-23874	70	19	disc	disc	NOUN
brj-23874	70	20	included	include	VERB
brj-23874	70	21	for	for	ADP
brj-23874	70	22	comparison	comparison	NOUN
brj-23874	70	23	.	.	PUNCT
brj-23874	71	1	in	in	ADP
brj-23874	71	2	this	this	DET
brj-23874	71	3	study	study	NOUN
brj-23874	71	4	,	,	PUNCT
brj-23874	71	5	ampicillin	ampicillin	NOUN
brj-23874	71	6	and	and	CCONJ
brj-23874	71	7	dmso	dmso	NOUN
brj-23874	71	8	were	be	AUX
brj-23874	71	9	used	use	VERB
brj-23874	71	10	as	as	ADP
brj-23874	71	11	positive	positive	ADJ
brj-23874	71	12	and	and	CCONJ
brj-23874	71	13	negative	negative	ADJ
brj-23874	71	14	control	control	NOUN
brj-23874	71	15	,	,	PUNCT
brj-23874	71	16	respectively	respectively	ADV
brj-23874	71	17	.	.	PUNCT
brj-23874	72	1	peer	peer	NOUN
brj-23874	72	2	-	-	PUNCT
brj-23874	72	3	reviewed	review	VERB
brj-23874	72	4	article	article	NOUN
brj-23874	72	5	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	72	6	zhu	zhu	PROPN
brj-23874	72	7	et	et	PROPN
brj-23874	72	8	al	al	PROPN
brj-23874	72	9	.	.	PROPN
brj-23874	73	1	(	(	PUNCT
brj-23874	73	2	2026	2026	NUM
brj-23874	73	3	)	)	PUNCT
brj-23874	73	4	.	.	PUNCT
brj-23874	74	1	“	"	PUNCT
brj-23874	74	2	pain	pain	NOUN
brj-23874	74	3	control	control	NOUN
brj-23874	74	4	with	with	ADP
brj-23874	74	5	seed	seed	NOUN
brj-23874	74	6	extract	extract	NOUN
brj-23874	74	7	,	,	PUNCT
brj-23874	74	8	”	"	PUNCT
brj-23874	74	9	bioresources	bioresource	NOUN
brj-23874	74	10	21(1	21(1	NUM
brj-23874	74	11	)	)	PUNCT
brj-23874	74	12	,	,	PUNCT
brj-23874	74	13	116	116	NUM
brj-23874	74	14	-	-	SYM
brj-23874	74	15	127	127	NUM
brj-23874	74	16	.	.	PUNCT
brj-23874	75	1	119	119	NUM
brj-23874	75	2	experimental	experimental	ADJ
brj-23874	75	3	section	section	NOUN
brj-23874	75	4	animals	animal	NOUN
brj-23874	75	5	in	in	ADP
brj-23874	75	6	this	this	DET
brj-23874	75	7	study	study	NOUN
brj-23874	75	8	,	,	PUNCT
brj-23874	75	9	60	60	NUM
brj-23874	75	10	4to	4to	ADJ
brj-23874	75	11	6	6	NUM
brj-23874	75	12	-	-	PUNCT
brj-23874	75	13	month	month	NOUN
brj-23874	75	14	-	-	PUNCT
brj-23874	75	15	old	old	ADJ
brj-23874	75	16	wistar	wistar	PROPN
brj-23874	75	17	albino	albino	PROPN
brj-23874	75	18	rats	rat	NOUN
brj-23874	75	19	weighing	weigh	VERB
brj-23874	75	20	150	150	NUM
brj-23874	75	21	to	to	ADP
brj-23874	75	22	200	200	NUM
brj-23874	75	23	g	g	NOUN
brj-23874	75	24	,	,	PUNCT
brj-23874	75	25	and	and	CCONJ
brj-23874	75	26	60	60	NUM
brj-23874	75	27	male	male	ADJ
brj-23874	75	28	and	and	CCONJ
brj-23874	75	29	female	female	ADJ
brj-23874	75	30	swiss	swiss	ADJ
brj-23874	75	31	albino	albino	NOUN
brj-23874	75	32	mice	mouse	NOUN
brj-23874	75	33	weighing	weigh	VERB
brj-23874	75	34	between	between	ADP
brj-23874	75	35	22	22	NUM
brj-23874	75	36	to	to	PART
brj-23874	75	37	35	35	NUM
brj-23874	75	38	g	g	NOUN
brj-23874	75	39	underwent	undergo	VERB
brj-23874	75	40	a	a	DET
brj-23874	75	41	14	14	NUM
brj-23874	75	42	-	-	PUNCT
brj-23874	75	43	day	day	NOUN
brj-23874	75	44	acclimatisation	acclimatisation	NOUN
brj-23874	75	45	period	period	NOUN
brj-23874	75	46	under	under	ADP
brj-23874	75	47	standardised	standardised	ADJ
brj-23874	75	48	housing	housing	NOUN
brj-23874	75	49	conditions	condition	NOUN
brj-23874	75	50	.	.	PUNCT
brj-23874	76	1	both	both	CCONJ
brj-23874	76	2	the	the	DET
brj-23874	76	3	mice	mouse	NOUN
brj-23874	76	4	and	and	CCONJ
brj-23874	76	5	rats	rat	NOUN
brj-23874	76	6	were	be	AUX
brj-23874	76	7	housed	house	VERB
brj-23874	76	8	in	in	ADP
brj-23874	76	9	cages	cage	NOUN
brj-23874	76	10	kept	keep	VERB
brj-23874	76	11	at	at	ADP
brj-23874	76	12	room	room	NOUN
brj-23874	76	13	temperature	temperature	NOUN
brj-23874	76	14	that	that	PRON
brj-23874	76	15	had	have	VERB
brj-23874	76	16	a	a	DET
brj-23874	76	17	12	12	NUM
brj-23874	76	18	h	h	NOUN
brj-23874	76	19	light	light	ADJ
brj-23874	76	20	-	-	PUNCT
brj-23874	76	21	dark	dark	NOUN
brj-23874	76	22	cycle	cycle	NOUN
brj-23874	76	23	and	and	CCONJ
brj-23874	76	24	provided	provide	VERB
brj-23874	76	25	with	with	ADP
brj-23874	76	26	a	a	DET
brj-23874	76	27	regular	regular	ADJ
brj-23874	76	28	pellet	pellet	NOUN
brj-23874	76	29	meal	meal	NOUN
brj-23874	76	30	and	and	CCONJ
brj-23874	76	31	unlimited	unlimited	ADJ
brj-23874	76	32	access	access	NOUN
brj-23874	76	33	to	to	ADP
brj-23874	76	34	water	water	NOUN
brj-23874	76	35	.	.	PUNCT
brj-23874	77	1	the	the	DET
brj-23874	77	2	present	present	ADJ
brj-23874	77	3	study	study	NOUN
brj-23874	77	4	’s	’s	PART
brj-23874	77	5	methodology	methodology	NOUN
brj-23874	77	6	and	and	CCONJ
brj-23874	77	7	procedures	procedure	NOUN
brj-23874	77	8	were	be	AUX
brj-23874	77	9	conducted	conduct	VERB
brj-23874	77	10	in	in	ADP
brj-23874	77	11	strict	strict	ADJ
brj-23874	77	12	accordance	accordance	NOUN
brj-23874	77	13	with	with	ADP
brj-23874	77	14	the	the	DET
brj-23874	77	15	established	establish	VERB
brj-23874	77	16	recommendations	recommendation	NOUN
brj-23874	77	17	for	for	ADP
brj-23874	77	18	the	the	DET
brj-23874	77	19	care	care	NOUN
brj-23874	77	20	and	and	CCONJ
brj-23874	77	21	use	use	NOUN
brj-23874	77	22	of	of	ADP
brj-23874	77	23	laboratory	laboratory	NOUN
brj-23874	77	24	animals	animal	NOUN
brj-23874	77	25	(	(	PUNCT
brj-23874	77	26	guide	guide	VERB
brj-23874	77	27	for	for	ADP
brj-23874	77	28	the	the	DET
brj-23874	77	29	care	care	NOUN
brj-23874	77	30	and	and	CCONJ
brj-23874	77	31	use	use	NOUN
brj-23874	77	32	of	of	ADP
brj-23874	77	33	laboratory	laboratory	NOUN
brj-23874	77	34	animals	animal	NOUN
brj-23874	77	35	2024	2024	NUM
brj-23874	77	36	)	)	PUNCT
brj-23874	77	37	.	.	PUNCT
brj-23874	78	1	grouping	group	VERB
brj-23874	78	2	and	and	CCONJ
brj-23874	78	3	dosing	dose	VERB
brj-23874	78	4	there	there	PRON
brj-23874	78	5	were	be	VERB
brj-23874	78	6	five	five	NUM
brj-23874	78	7	different	different	ADJ
brj-23874	78	8	groups	group	NOUN
brj-23874	78	9	of	of	ADP
brj-23874	78	10	mice	mouse	NOUN
brj-23874	78	11	,	,	PUNCT
brj-23874	78	12	each	each	PRON
brj-23874	78	13	consisting	consist	VERB
brj-23874	78	14	of	of	ADP
brj-23874	78	15	six	six	NUM
brj-23874	78	16	animals	animal	NOUN
brj-23874	78	17	.	.	PUNCT
brj-23874	79	1	group	group	NOUN
brj-23874	79	2	i	i	PRON
brj-23874	79	3	was	be	AUX
brj-23874	79	4	given	give	VERB
brj-23874	79	5	distilled	distil	VERB
brj-23874	79	6	water	water	NOUN
brj-23874	79	7	as	as	ADP
brj-23874	79	8	negative	negative	ADJ
brj-23874	79	9	control	control	NOUN
brj-23874	79	10	.	.	PUNCT
brj-23874	80	1	the	the	DET
brj-23874	80	2	extract	extract	NOUN
brj-23874	80	3	was	be	AUX
brj-23874	80	4	administered	administer	VERB
brj-23874	80	5	to	to	ADP
brj-23874	80	6	groups	groups	PROPN
brj-23874	80	7	ii	ii	PROPN
brj-23874	80	8	,	,	PUNCT
brj-23874	80	9	iii	iii	PROPN
brj-23874	80	10	,	,	PUNCT
brj-23874	80	11	and	and	CCONJ
brj-23874	80	12	iv	iv	NUM
brj-23874	80	13	at	at	ADP
brj-23874	80	14	doses	dose	NOUN
brj-23874	80	15	of	of	ADP
brj-23874	80	16	100	100	NUM
brj-23874	80	17	,	,	PUNCT
brj-23874	80	18	200	200	NUM
brj-23874	80	19	,	,	PUNCT
brj-23874	80	20	and	and	CCONJ
brj-23874	80	21	400	400	NUM
brj-23874	80	22	mg	mg	NUM
brj-23874	80	23	/	/	SYM
brj-23874	80	24	kg	kg	PROPN
brj-23874	80	25	,	,	PUNCT
brj-23874	80	26	respectively	respectively	ADV
brj-23874	80	27	.	.	PUNCT
brj-23874	81	1	these	these	DET
brj-23874	81	2	dosages	dosage	NOUN
brj-23874	81	3	were	be	AUX
brj-23874	81	4	chosen	choose	VERB
brj-23874	81	5	based	base	VERB
brj-23874	81	6	on	on	ADP
brj-23874	81	7	prior	prior	ADJ
brj-23874	81	8	studies	study	NOUN
brj-23874	81	9	on	on	ADP
brj-23874	81	10	acute	acute	ADJ
brj-23874	81	11	toxicity	toxicity	NOUN
brj-23874	81	12	(	(	PUNCT
brj-23874	81	13	mergia	mergia	PROPN
brj-23874	81	14	et	et	PROPN
brj-23874	81	15	al	al	PROPN
brj-23874	81	16	2016	2016	NUM
brj-23874	81	17	)	)	PUNCT
brj-23874	81	18	.	.	PUNCT
brj-23874	82	1	morphine	morphine	PROPN
brj-23874	82	2	,	,	PUNCT
brj-23874	82	3	the	the	DET
brj-23874	82	4	common	common	ADJ
brj-23874	82	5	painkiller	painkiller	NOUN
brj-23874	82	6	,	,	PUNCT
brj-23874	82	7	was	be	AUX
brj-23874	82	8	given	give	VERB
brj-23874	82	9	to	to	ADP
brj-23874	82	10	group	group	NOUN
brj-23874	82	11	v	v	NOUN
brj-23874	82	12	at	at	ADP
brj-23874	82	13	a	a	DET
brj-23874	82	14	dose	dose	NOUN
brj-23874	82	15	of	of	ADP
brj-23874	82	16	10	10	NUM
brj-23874	82	17	mg	mg	PROPN
brj-23874	82	18	/	/	SYM
brj-23874	82	19	kg	kg	PROPN
brj-23874	82	20	.	.	PUNCT
brj-23874	83	1	the	the	DET
brj-23874	83	2	gastric	gastric	ADJ
brj-23874	83	3	gavage	gavage	NOUN
brj-23874	83	4	technique	technique	NOUN
brj-23874	83	5	was	be	AUX
brj-23874	83	6	utilised	utilise	VERB
brj-23874	83	7	to	to	PART
brj-23874	83	8	administer	administer	VERB
brj-23874	83	9	these	these	DET
brj-23874	83	10	drugs	drug	NOUN
brj-23874	83	11	orally	orally	ADV
brj-23874	83	12	.	.	PUNCT
brj-23874	84	1	analgesic	analgesic	ADJ
brj-23874	84	2	activity	activity	NOUN
brj-23874	84	3	hot	hot	ADJ
brj-23874	84	4	plate	plate	NOUN
brj-23874	84	5	method	method	NOUN
brj-23874	84	6	every	every	DET
brj-23874	84	7	mouse	mouse	NOUN
brj-23874	84	8	was	be	AUX
brj-23874	84	9	placed	place	VERB
brj-23874	84	10	on	on	ADP
brj-23874	84	11	a	a	DET
brj-23874	84	12	heated	heated	ADJ
brj-23874	84	13	plate	plate	NOUN
brj-23874	84	14	with	with	ADP
brj-23874	84	15	a	a	DET
brj-23874	84	16	precisely	precisely	ADV
brj-23874	84	17	regulated	regulated	ADJ
brj-23874	84	18	temperature	temperature	NOUN
brj-23874	84	19	of	of	ADP
brj-23874	84	20	55	55	NUM
brj-23874	84	21	±	±	NUM
brj-23874	84	22	1	1	NUM
brj-23874	84	23	°	°	NOUN
brj-23874	84	24	c	c	NOUN
brj-23874	84	25	.	.	PUNCT
brj-23874	85	1	for	for	SCONJ
brj-23874	85	2	every	every	DET
brj-23874	85	3	mouse	mouse	NOUN
brj-23874	85	4	observed	observe	VERB
brj-23874	85	5	,	,	PUNCT
brj-23874	85	6	the	the	DET
brj-23874	85	7	time	time	NOUN
brj-23874	85	8	in	in	ADP
brj-23874	85	9	seconds	second	NOUN
brj-23874	85	10	between	between	ADP
brj-23874	85	11	when	when	SCONJ
brj-23874	85	12	it	it	PRON
brj-23874	85	13	was	be	AUX
brj-23874	85	14	put	put	VERB
brj-23874	85	15	on	on	ADP
brj-23874	85	16	the	the	DET
brj-23874	85	17	hot	hot	ADJ
brj-23874	85	18	plate	plate	NOUN
brj-23874	85	19	and	and	CCONJ
brj-23874	85	20	when	when	SCONJ
brj-23874	85	21	it	it	PRON
brj-23874	85	22	began	begin	VERB
brj-23874	85	23	to	to	PART
brj-23874	85	24	show	show	VERB
brj-23874	85	25	signs	sign	NOUN
brj-23874	85	26	of	of	ADP
brj-23874	85	27	discomfort	discomfort	NOUN
brj-23874	85	28	(	(	PUNCT
brj-23874	85	29	e.g.	e.g.	ADV
brj-23874	85	30	,	,	PUNCT
brj-23874	85	31	kicking	kicking	NOUN
brj-23874	85	32	,	,	PUNCT
brj-23874	85	33	jumping	jump	VERB
brj-23874	85	34	,	,	PUNCT
brj-23874	85	35	licking	lick	VERB
brj-23874	85	36	,	,	PUNCT
brj-23874	85	37	or	or	CCONJ
brj-23874	85	38	covering	cover	VERB
brj-23874	85	39	its	its	PRON
brj-23874	85	40	rear	rear	ADJ
brj-23874	85	41	limbs	limb	NOUN
brj-23874	85	42	)	)	PUNCT
brj-23874	85	43	was	be	AUX
brj-23874	85	44	carefully	carefully	ADV
brj-23874	85	45	noted	note	VERB
brj-23874	85	46	.	.	PUNCT
brj-23874	86	1	the	the	DET
brj-23874	86	2	time	time	NOUN
brj-23874	86	3	limit	limit	NOUN
brj-23874	86	4	was	be	AUX
brj-23874	86	5	set	set	VERB
brj-23874	86	6	at	at	ADP
brj-23874	86	7	15	15	NUM
brj-23874	86	8	s	s	NOUN
brj-23874	86	9	to	to	PART
brj-23874	86	10	prevent	prevent	VERB
brj-23874	86	11	the	the	DET
brj-23874	86	12	animals	animal	NOUN
brj-23874	86	13	’	’	PART
brj-23874	86	14	paws	paw	NOUN
brj-23874	86	15	from	from	ADP
brj-23874	86	16	being	be	AUX
brj-23874	86	17	burned	burn	VERB
brj-23874	86	18	.	.	PUNCT
brj-23874	87	1	before	before	SCONJ
brj-23874	87	2	the	the	DET
brj-23874	87	3	c.	c.	PROPN
brj-23874	87	4	colocynthis	colocynthis	PROPN
brj-23874	87	5	extract	extract	NOUN
brj-23874	87	6	was	be	AUX
brj-23874	87	7	applied	apply	VERB
brj-23874	87	8	and	and	CCONJ
brj-23874	87	9	30	30	NUM
brj-23874	87	10	,	,	PUNCT
brj-23874	87	11	60	60	NUM
brj-23874	87	12	,	,	PUNCT
brj-23874	87	13	90	90	NUM
brj-23874	87	14	,	,	PUNCT
brj-23874	87	15	and	and	CCONJ
brj-23874	87	16	120	120	NUM
brj-23874	87	17	min	min	NOUN
brj-23874	87	18	afterward	afterward	ADV
brj-23874	87	19	,	,	PUNCT
brj-23874	87	20	the	the	DET
brj-23874	87	21	times	time	NOUN
brj-23874	87	22	at	at	ADP
brj-23874	87	23	which	which	PRON
brj-23874	87	24	the	the	DET
brj-23874	87	25	animals	animal	NOUN
brj-23874	87	26	reacted	react	VERB
brj-23874	87	27	to	to	ADP
brj-23874	87	28	the	the	DET
brj-23874	87	29	pain	pain	NOUN
brj-23874	87	30	were	be	AUX
brj-23874	87	31	meticulously	meticulously	ADV
brj-23874	87	32	recorded	record	VERB
brj-23874	87	33	.	.	PUNCT
brj-23874	88	1	this	this	DET
brj-23874	88	2	process	process	NOUN
brj-23874	88	3	made	make	VERB
brj-23874	88	4	it	it	PRON
brj-23874	88	5	possible	possible	ADJ
brj-23874	88	6	to	to	PART
brj-23874	88	7	thoroughly	thoroughly	ADV
brj-23874	88	8	assess	assess	VERB
brj-23874	88	9	how	how	SCONJ
brj-23874	88	10	well	well	ADV
brj-23874	88	11	the	the	DET
brj-23874	88	12	extract	extract	NOUN
brj-23874	88	13	reduced	reduce	VERB
brj-23874	88	14	pain	pain	NOUN
brj-23874	88	15	over	over	ADP
brj-23874	88	16	time	time	NOUN
brj-23874	88	17	and	and	CCONJ
brj-23874	88	18	at	at	ADP
brj-23874	88	19	different	different	ADJ
brj-23874	88	20	dosages	dosage	NOUN
brj-23874	88	21	.	.	PUNCT
brj-23874	89	1	an	an	DET
brj-23874	89	2	analysis	analysis	NOUN
brj-23874	89	3	was	be	AUX
brj-23874	89	4	conducted	conduct	VERB
brj-23874	89	5	to	to	PART
brj-23874	89	6	determine	determine	VERB
brj-23874	89	7	how	how	SCONJ
brj-23874	89	8	long	long	ADV
brj-23874	89	9	it	it	PRON
brj-23874	89	10	took	take	VERB
brj-23874	89	11	the	the	DET
brj-23874	89	12	treated	treat	VERB
brj-23874	89	13	groups	group	NOUN
brj-23874	89	14	to	to	PART
brj-23874	89	15	react	react	VERB
brj-23874	89	16	more	more	ADV
brj-23874	89	17	slowly	slowly	ADV
brj-23874	89	18	than	than	ADP
brj-23874	89	19	the	the	DET
brj-23874	89	20	control	control	PROPN
brj-23874	89	21	group	group	NOUN
brj-23874	89	22	’s	’s	PART
brj-23874	89	23	baseline	baseline	NOUN
brj-23874	89	24	.	.	PUNCT
brj-23874	90	1	using	use	VERB
brj-23874	90	2	a	a	DET
brj-23874	90	3	preset	preset	ADJ
brj-23874	90	4	method	method	NOUN
brj-23874	90	5	,	,	PUNCT
brj-23874	90	6	the	the	DET
brj-23874	90	7	percentage	percentage	NOUN
brj-23874	90	8	of	of	ADP
brj-23874	90	9	the	the	DET
brj-23874	90	10	maximal	maximal	ADJ
brj-23874	90	11	potential	potential	ADJ
brj-23874	90	12	antinociceptive	antinociceptive	ADJ
brj-23874	90	13	effect	effect	NOUN
brj-23874	90	14	was	be	AUX
brj-23874	90	15	evaluated	evaluate	VERB
brj-23874	90	16	to	to	PART
brj-23874	90	17	assess	assess	VERB
brj-23874	90	18	the	the	DET
brj-23874	90	19	efficacy	efficacy	NOUN
brj-23874	90	20	of	of	ADP
brj-23874	90	21	the	the	DET
brj-23874	90	22	treatment	treatment	NOUN
brj-23874	90	23	(	(	PUNCT
brj-23874	90	24	abbas	abbas	PROPN
brj-23874	90	25	(	(	PUNCT
brj-23874	90	26	2013	2013	NUM
brj-23874	90	27	)	)	PUNCT
brj-23874	90	28	.	.	PUNCT
brj-23874	91	1	(	(	PUNCT
brj-23874	91	2	1	1	X
brj-23874	91	3	)	)	PUNCT
brj-23874	91	4	anti	anti	ADJ
brj-23874	91	5	-	-	ADJ
brj-23874	91	6	inflammatory	inflammatory	ADJ
brj-23874	91	7	activity	activity	NOUN
brj-23874	91	8	anti	anti	ADJ
brj-23874	91	9	-	-	ADJ
brj-23874	91	10	inflammatory	inflammatory	ADJ
brj-23874	91	11	properties	property	NOUN
brj-23874	91	12	were	be	AUX
brj-23874	91	13	studied	study	VERB
brj-23874	91	14	using	use	VERB
brj-23874	91	15	rat	rat	NOUN
brj-23874	91	16	models	model	NOUN
brj-23874	91	17	and	and	CCONJ
brj-23874	91	18	the	the	DET
brj-23874	91	19	carrageenaninduced	carrageenaninduce	VERB
brj-23874	91	20	paw	paw	NOUN
brj-23874	91	21	swelling	swelling	NOUN
brj-23874	91	22	approach	approach	NOUN
brj-23874	91	23	.	.	PUNCT
brj-23874	92	1	the	the	DET
brj-23874	92	2	male	male	PROPN
brj-23874	92	3	albino	albino	NOUN
brj-23874	92	4	wistar	wistar	PROPN
brj-23874	92	5	rats	rat	NOUN
brj-23874	92	6	used	use	VERB
brj-23874	92	7	in	in	ADP
brj-23874	92	8	this	this	DET
brj-23874	92	9	experiment	experiment	NOUN
brj-23874	92	10	weighed	weigh	VERB
brj-23874	92	11	between	between	ADP
brj-23874	92	12	150	150	NUM
brj-23874	92	13	and	and	CCONJ
brj-23874	92	14	200	200	NUM
brj-23874	92	15	g	g	NOUN
brj-23874	92	16	,	,	PUNCT
brj-23874	92	17	with	with	ADP
brj-23874	92	18	6	6	NUM
brj-23874	92	19	animals	animal	NOUN
brj-23874	92	20	per	per	ADP
brj-23874	92	21	experimental	experimental	ADJ
brj-23874	92	22	group	group	NOUN
brj-23874	92	23	and	and	CCONJ
brj-23874	92	24	these	these	DET
brj-23874	92	25	rats	rat	NOUN
brj-23874	92	26	were	be	AUX
brj-23874	92	27	given	give	VERB
brj-23874	92	28	unlimited	unlimited	ADJ
brj-23874	92	29	access	access	NOUN
brj-23874	92	30	to	to	ADP
brj-23874	92	31	water	water	NOUN
brj-23874	92	32	but	but	CCONJ
brj-23874	92	33	fasted	fast	VERB
brj-23874	92	34	for	for	ADP
brj-23874	92	35	24	24	NUM
brj-23874	92	36	h	h	NOUN
brj-23874	92	37	prior	prior	ADV
brj-23874	92	38	to	to	AUX
brj-23874	92	39	test	test	NOUN
brj-23874	92	40	.	.	PUNCT
brj-23874	93	1	an	an	DET
brj-23874	93	2	hour	hour	NOUN
brj-23874	93	3	prior	prior	ADV
brj-23874	93	4	to	to	ADP
brj-23874	93	5	the	the	DET
brj-23874	93	6	test	test	NOUN
brj-23874	93	7	,	,	PUNCT
brj-23874	93	8	50	50	NUM
brj-23874	93	9	µl	µl	NOUN
brj-23874	93	10	of	of	ADP
brj-23874	93	11	a	a	DET
brj-23874	93	12	1	1	NUM
brj-23874	93	13	%	%	NOUN
brj-23874	93	14	carrageenan	carrageenan	NOUN
brj-23874	93	15	in	in	ADP
brj-23874	93	16	saline	saline	ADJ
brj-23874	93	17	solution	solution	NOUN
brj-23874	93	18	were	be	AUX
brj-23874	93	19	prepared	prepare	VERB
brj-23874	93	20	and	and	CCONJ
brj-23874	93	21	injected	inject	VERB
brj-23874	93	22	under	under	ADP
brj-23874	93	23	the	the	DET
brj-23874	93	24	rats	rat	NOUN
brj-23874	93	25	’	'	PUNCT
brj-23874	93	26	rear	rear	ADJ
brj-23874	93	27	paws	paw	NOUN
brj-23874	93	28	.	.	PUNCT
brj-23874	94	1	the	the	DET
brj-23874	94	2	c.	c.	PROPN
brj-23874	94	3	colocynthis	colocynthis	PROPN
brj-23874	94	4	extract	extract	NOUN
brj-23874	94	5	was	be	AUX
brj-23874	94	6	combined	combine	VERB
brj-23874	94	7	with	with	ADP
brj-23874	94	8	indomethacin	indomethacin	NOUN
brj-23874	94	9	in	in	ADP
brj-23874	94	10	a	a	DET
brj-23874	94	11	solution	solution	NOUN
brj-23874	94	12	that	that	PRON
brj-23874	94	13	was	be	AUX
brj-23874	94	14	combined	combine	VERB
brj-23874	94	15	with	with	ADP
brj-23874	94	16	a	a	DET
brj-23874	94	17	0.9	0.9	NUM
brj-23874	94	18	%	%	NOUN
brj-23874	94	19	w	w	NOUN
brj-23874	94	20	/	/	SYM
brj-23874	94	21	v	v	NOUN
brj-23874	94	22	saline	saline	NOUN
brj-23874	94	23	solution	solution	NOUN
brj-23874	94	24	and	and	CCONJ
brj-23874	94	25	polysorbate	polysorbate	NOUN
brj-23874	94	26	80	80	NUM
brj-23874	94	27	(	(	PUNCT
brj-23874	94	28	tween	tween	NOUN
brj-23874	94	29	80	80	NUM
brj-23874	94	30	)	)	PUNCT
brj-23874	94	31	.	.	PUNCT
brj-23874	95	1	the	the	DET
brj-23874	95	2	final	final	ADJ
brj-23874	95	3	concentration	concentration	NOUN
brj-23874	95	4	of	of	ADP
brj-23874	95	5	polysorbate	polysorbate	NOUN
brj-23874	95	6	80	80	NUM
brj-23874	95	7	was	be	AUX
brj-23874	95	8	maintained	maintain	VERB
brj-23874	95	9	below	below	ADP
brj-23874	95	10	5	5	NUM
brj-23874	95	11	%	%	NOUN
brj-23874	95	12	to	to	PART
brj-23874	95	13	avoid	avoid	VERB
brj-23874	95	14	any	any	DET
brj-23874	95	15	solventinduced	solventinduced	ADJ
brj-23874	95	16	side	side	NOUN
brj-23874	95	17	effects	effect	NOUN
brj-23874	95	18	.	.	PUNCT
brj-23874	96	1	intraperitoneal	intraperitoneal	ADJ
brj-23874	96	2	injections	injection	NOUN
brj-23874	96	3	of	of	ADP
brj-23874	96	4	indomethacin	indomethacin	NOUN
brj-23874	96	5	(	(	PUNCT
brj-23874	96	6	5	5	NUM
brj-23874	96	7	,	,	PUNCT
brj-23874	96	8	10	10	NUM
brj-23874	96	9	,	,	PUNCT
brj-23874	96	10	and	and	CCONJ
brj-23874	96	11	15	15	NUM
brj-23874	96	12	mg	mg	NUM
brj-23874	96	13	/	/	SYM
brj-23874	96	14	kg	kg	NOUN
brj-23874	96	15	)	)	PUNCT
brj-23874	96	16	and	and	CCONJ
brj-23874	96	17	peer	peer	NOUN
brj-23874	96	18	-	-	PUNCT
brj-23874	96	19	reviewed	review	VERB
brj-23874	96	20	article	article	NOUN
brj-23874	96	21	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	96	22	zhu	zhu	PROPN
brj-23874	96	23	et	et	PROPN
brj-23874	96	24	al	al	PROPN
brj-23874	96	25	.	.	PROPN
brj-23874	97	1	(	(	PUNCT
brj-23874	97	2	2026	2026	NUM
brj-23874	97	3	)	)	PUNCT
brj-23874	97	4	.	.	PUNCT
brj-23874	98	1	“	"	PUNCT
brj-23874	98	2	pain	pain	NOUN
brj-23874	98	3	control	control	NOUN
brj-23874	98	4	with	with	ADP
brj-23874	98	5	seed	seed	NOUN
brj-23874	98	6	extract	extract	NOUN
brj-23874	98	7	,	,	PUNCT
brj-23874	98	8	”	"	PUNCT
brj-23874	98	9	bioresources	bioresource	NOUN
brj-23874	98	10	21(1	21(1	NUM
brj-23874	98	11	)	)	PUNCT
brj-23874	98	12	,	,	PUNCT
brj-23874	98	13	116	116	NUM
brj-23874	98	14	-	-	SYM
brj-23874	98	15	127	127	NUM
brj-23874	98	16	.	.	PUNCT
brj-23874	99	1	120	120	NUM
brj-23874	99	2	the	the	DET
brj-23874	99	3	extract	extract	NOUN
brj-23874	99	4	(	(	PUNCT
brj-23874	99	5	50	50	NUM
brj-23874	99	6	,	,	PUNCT
brj-23874	99	7	100	100	NUM
brj-23874	99	8	,	,	PUNCT
brj-23874	99	9	and	and	CCONJ
brj-23874	99	10	150	150	NUM
brj-23874	99	11	mg	mg	NUM
brj-23874	99	12	/	/	SYM
brj-23874	99	13	kg	kg	NOUN
brj-23874	99	14	)	)	PUNCT
brj-23874	99	15	were	be	AUX
brj-23874	99	16	used	use	VERB
brj-23874	99	17	.	.	PUNCT
brj-23874	100	1	these	these	DET
brj-23874	100	2	shots	shot	NOUN
brj-23874	100	3	were	be	AUX
brj-23874	100	4	administered	administer	VERB
brj-23874	100	5	1	1	NUM
brj-23874	100	6	h	h	NOUN
brj-23874	100	7	before	before	SCONJ
brj-23874	100	8	the	the	DET
brj-23874	100	9	carrageenan	carrageenan	NOUN
brj-23874	100	10	was	be	AUX
brj-23874	100	11	applied	apply	VERB
brj-23874	100	12	.	.	PUNCT
brj-23874	101	1	after	after	ADP
brj-23874	101	2	the	the	DET
brj-23874	101	3	carrageenan	carrageenan	NOUN
brj-23874	101	4	injection	injection	NOUN
brj-23874	101	5	,	,	PUNCT
brj-23874	101	6	paw	paw	NOUN
brj-23874	101	7	volumes	volume	NOUN
brj-23874	101	8	were	be	AUX
brj-23874	101	9	measured	measure	VERB
brj-23874	101	10	using	use	VERB
brj-23874	101	11	a	a	DET
brj-23874	101	12	plethysmometer	plethysmometer	NOUN
brj-23874	101	13	both	both	CCONJ
brj-23874	101	14	right	right	ADV
brj-23874	101	15	away	away	ADV
brj-23874	101	16	and	and	CCONJ
brj-23874	101	17	for	for	ADP
brj-23874	101	18	up	up	ADP
brj-23874	101	19	to	to	PART
brj-23874	101	20	4	4	NUM
brj-23874	101	21	h	h	NOUN
brj-23874	101	22	afterward	afterward	ADV
brj-23874	101	23	.	.	PUNCT
brj-23874	102	1	the	the	DET
brj-23874	102	2	amount	amount	NOUN
brj-23874	102	3	of	of	ADP
brj-23874	102	4	the	the	DET
brj-23874	102	5	induced	induced	ADJ
brj-23874	102	6	swelling	swelling	NOUN
brj-23874	102	7	was	be	AUX
brj-23874	102	8	ascertained	ascertain	VERB
brj-23874	102	9	by	by	ADP
brj-23874	102	10	dividing	divide	VERB
brj-23874	102	11	the	the	DET
brj-23874	102	12	total	total	ADJ
brj-23874	102	13	volumes	volume	NOUN
brj-23874	102	14	of	of	ADP
brj-23874	102	15	the	the	DET
brj-23874	102	16	hind	hind	NOUN
brj-23874	102	17	paws	paw	NOUN
brj-23874	102	18	before	before	ADV
brj-23874	102	19	and	and	CCONJ
brj-23874	102	20	after	after	ADP
brj-23874	102	21	the	the	DET
brj-23874	102	22	application	application	NOUN
brj-23874	102	23	of	of	ADP
brj-23874	102	24	carrageenan	carrageenan	NOUN
brj-23874	102	25	.	.	PUNCT
brj-23874	103	1	ratios	ratio	NOUN
brj-23874	103	2	<	<	X
brj-23874	103	3	1.5	1.5	NUM
brj-23874	103	4	after	after	SCONJ
brj-23874	103	5	treatment	treatment	NOUN
brj-23874	103	6	demonstrated	demonstrate	VERB
brj-23874	103	7	a	a	DET
brj-23874	103	8	marked	mark	VERB
brj-23874	103	9	decrease	decrease	NOUN
brj-23874	103	10	in	in	ADP
brj-23874	103	11	edema	edema	NOUN
brj-23874	103	12	,	,	PUNCT
brj-23874	103	13	demonstrating	demonstrate	VERB
brj-23874	103	14	the	the	DET
brj-23874	103	15	strong	strong	ADJ
brj-23874	103	16	anti	anti	ADJ
brj-23874	103	17	-	-	ADJ
brj-23874	103	18	inflammatory	inflammatory	ADJ
brj-23874	103	19	effects	effect	NOUN
brj-23874	103	20	of	of	ADP
brj-23874	103	21	the	the	DET
brj-23874	103	22	drugs	drug	NOUN
brj-23874	103	23	given	give	VERB
brj-23874	103	24	(	(	PUNCT
brj-23874	103	25	chi	chi	NOUN
brj-23874	103	26	and	and	CCONJ
brj-23874	103	27	jun	jun	PROPN
brj-23874	103	28	1990	1990	NUM
brj-23874	103	29	)	)	PUNCT
brj-23874	103	30	.	.	PUNCT
brj-23874	104	1	the	the	DET
brj-23874	104	2	present	present	ADJ
brj-23874	104	3	animal	animal	NOUN
brj-23874	104	4	research	research	NOUN
brj-23874	104	5	was	be	AUX
brj-23874	104	6	carried	carry	VERB
brj-23874	104	7	out	out	ADP
brj-23874	104	8	in	in	ADP
brj-23874	104	9	line	line	NOUN
brj-23874	104	10	with	with	ADP
brj-23874	104	11	the	the	DET
brj-23874	104	12	principles	principle	NOUN
brj-23874	104	13	and	and	CCONJ
brj-23874	104	14	standards	standard	NOUN
brj-23874	104	15	outlined	outline	VERB
brj-23874	104	16	in	in	ADP
brj-23874	104	17	the	the	DET
brj-23874	104	18	institutional	institutional	ADJ
brj-23874	104	19	ethical	ethical	ADJ
brj-23874	104	20	committee	committee	NOUN
brj-23874	104	21	of	of	ADP
brj-23874	104	22	animal	animal	NOUN
brj-23874	104	23	experimentation	experimentation	NOUN
brj-23874	104	24	(	(	PUNCT
brj-23874	104	25	approval	approval	NOUN
brj-23874	104	26	number	number	NOUN
brj-23874	104	27	:	:	PUNCT
brj-23874	104	28	2022	2022	NUM
brj-23874	104	29	-	-	SYM
brj-23874	104	30	07	07	NUM
brj-23874	104	31	-	-	PUNCT
brj-23874	104	32	05	05	NUM
brj-23874	104	33	)	)	PUNCT
brj-23874	104	34	.	.	PUNCT
brj-23874	105	1	all	all	DET
brj-23874	105	2	the	the	DET
brj-23874	105	3	animal	animal	NOUN
brj-23874	105	4	experiments	experiment	NOUN
brj-23874	105	5	were	be	AUX
brj-23874	105	6	performed	perform	VERB
brj-23874	105	7	according	accord	VERB
brj-23874	105	8	to	to	ADP
brj-23874	105	9	ethical	ethical	ADJ
brj-23874	105	10	committee	committee	NOUN
brj-23874	105	11	guidelines	guideline	NOUN
brj-23874	105	12	of	of	ADP
brj-23874	105	13	shanghai	shanghai	PROPN
brj-23874	105	14	huashan	huashan	PROPN
brj-23874	105	15	hospital	hospital	PROPN
brj-23874	105	16	,	,	PUNCT
brj-23874	105	17	shanghai	shanghai	PROPN
brj-23874	105	18	.	.	PUNCT
brj-23874	106	1	statistical	statistical	ADJ
brj-23874	106	2	analysis	analysis	NOUN
brj-23874	106	3	the	the	DET
brj-23874	106	4	analysis	analysis	NOUN
brj-23874	106	5	was	be	AUX
brj-23874	106	6	conducted	conduct	VERB
brj-23874	106	7	using	use	VERB
brj-23874	106	8	statistical	statistical	ADJ
brj-23874	106	9	package	package	NOUN
brj-23874	106	10	for	for	ADP
brj-23874	106	11	social	social	ADJ
brj-23874	106	12	science	science	NOUN
brj-23874	106	13	(	(	PUNCT
brj-23874	106	14	spss	spss	PROPN
brj-23874	106	15	)	)	PUNCT
brj-23874	106	16	version	version	NOUN
brj-23874	106	17	25	25	NUM
brj-23874	106	18	and	and	CCONJ
brj-23874	106	19	graph	graph	VERB
brj-23874	106	20	pad	pad	NOUN
brj-23874	106	21	prism	prism	NOUN
brj-23874	106	22	version	version	NOUN
brj-23874	106	23	8.1	8.1	NUM
brj-23874	106	24	.	.	PUNCT
brj-23874	107	1	one	one	NUM
brj-23874	107	2	way	way	NOUN
brj-23874	107	3	analysis	analysis	NOUN
brj-23874	107	4	of	of	ADP
brj-23874	107	5	variance	variance	NOUN
brj-23874	107	6	(	(	PUNCT
brj-23874	107	7	anova	anova	PROPN
brj-23874	107	8	)	)	PUNCT
brj-23874	107	9	was	be	AUX
brj-23874	107	10	used	use	VERB
brj-23874	107	11	to	to	PART
brj-23874	107	12	analyze	analyze	VERB
brj-23874	107	13	the	the	DET
brj-23874	107	14	data	datum	NOUN
brj-23874	107	15	followed	follow	VERB
brj-23874	107	16	by	by	ADP
brj-23874	107	17	tukey	tukey	PROPN
brj-23874	107	18	post	post	X
brj-23874	107	19	hoc	hoc	X
brj-23874	107	20	test	test	NOUN
brj-23874	107	21	to	to	PART
brj-23874	107	22	determine	determine	VERB
brj-23874	107	23	statistical	statistical	ADJ
brj-23874	107	24	significance	significance	NOUN
brj-23874	107	25	.	.	PUNCT
brj-23874	108	1	all	all	DET
brj-23874	108	2	the	the	DET
brj-23874	108	3	data	datum	NOUN
brj-23874	108	4	were	be	AUX
brj-23874	108	5	expressed	express	VERB
brj-23874	108	6	as	as	ADP
brj-23874	108	7	mean	mean	NOUN
brj-23874	108	8	±	±	NUM
brj-23874	108	9	standard	standard	ADJ
brj-23874	108	10	error	error	NOUN
brj-23874	108	11	of	of	ADP
brj-23874	108	12	the	the	DET
brj-23874	108	13	mean	mean	NOUN
brj-23874	108	14	(	(	PUNCT
brj-23874	108	15	sem	sem	NOUN
brj-23874	108	16	)	)	PUNCT
brj-23874	108	17	.	.	PUNCT
brj-23874	109	1	p	p	NOUN
brj-23874	109	2	values	value	NOUN
brj-23874	109	3	≤	≤	NOUN
brj-23874	109	4	0.05	0.05	NUM
brj-23874	109	5	were	be	AUX
brj-23874	109	6	taken	take	VERB
brj-23874	109	7	as	as	ADP
brj-23874	109	8	statistically	statistically	ADV
brj-23874	109	9	significant	significant	ADJ
brj-23874	109	10	results	result	NOUN
brj-23874	109	11	and	and	CCONJ
brj-23874	109	12	discussion	discussion	NOUN
brj-23874	109	13	assessment	assessment	NOUN
brj-23874	109	14	of	of	ADP
brj-23874	109	15	cytotoxicity	cytotoxicity	NOUN
brj-23874	109	16	the	the	DET
brj-23874	109	17	effect	effect	NOUN
brj-23874	109	18	of	of	ADP
brj-23874	109	19	the	the	DET
brj-23874	109	20	c.	c.	PROPN
brj-23874	109	21	colocynthis	colocynthis	PROPN
brj-23874	109	22	extract	extract	NOUN
brj-23874	109	23	on	on	ADP
brj-23874	109	24	tumour	tumour	NOUN
brj-23874	109	25	cell	cell	NOUN
brj-23874	109	26	line	line	NOUN
brj-23874	109	27	survival	survival	NOUN
brj-23874	109	28	was	be	AUX
brj-23874	109	29	also	also	ADV
brj-23874	109	30	examined	examine	VERB
brj-23874	109	31	.	.	PUNCT
brj-23874	110	1	specifically	specifically	ADV
brj-23874	110	2	,	,	PUNCT
brj-23874	110	3	the	the	DET
brj-23874	110	4	mtt	mtt	NOUN
brj-23874	110	5	assay	assay	VERB
brj-23874	110	6	was	be	AUX
brj-23874	110	7	used	use	VERB
brj-23874	110	8	to	to	PART
brj-23874	110	9	investigate	investigate	VERB
brj-23874	110	10	the	the	DET
brj-23874	110	11	link	link	NOUN
brj-23874	110	12	between	between	ADP
brj-23874	110	13	the	the	DET
brj-23874	110	14	viability	viability	NOUN
brj-23874	110	15	of	of	ADP
brj-23874	110	16	b16f10	b16f10	ADJ
brj-23874	110	17	melanoma	melanoma	NOUN
brj-23874	110	18	cells	cell	NOUN
brj-23874	110	19	and	and	CCONJ
brj-23874	110	20	concentration	concentration	NOUN
brj-23874	110	21	of	of	ADP
brj-23874	110	22	the	the	DET
brj-23874	110	23	extract	extract	NOUN
brj-23874	110	24	.	.	PUNCT
brj-23874	111	1	different	different	ADJ
brj-23874	111	2	concentrations	concentration	NOUN
brj-23874	111	3	of	of	ADP
brj-23874	111	4	c.	c.	PROPN
brj-23874	111	5	colocynthis	colocynthis	PROPN
brj-23874	111	6	aqueous	aqueous	ADJ
brj-23874	111	7	extract	extract	NOUN
brj-23874	111	8	(	(	PUNCT
brj-23874	111	9	25	25	NUM
brj-23874	111	10	to	to	PART
brj-23874	111	11	150	150	NUM
brj-23874	111	12	μg	μg	NOUN
brj-23874	111	13	/	/	SYM
brj-23874	111	14	ml	ml	NOUN
brj-23874	111	15	)	)	PUNCT
brj-23874	111	16	were	be	AUX
brj-23874	111	17	applied	apply	VERB
brj-23874	111	18	to	to	ADP
brj-23874	111	19	b16f10	b16f10	ADJ
brj-23874	111	20	cells	cell	NOUN
brj-23874	111	21	for	for	ADP
brj-23874	111	22	24	24	NUM
brj-23874	111	23	h	h	NOUN
brj-23874	111	24	at	at	ADP
brj-23874	111	25	37	37	NUM
brj-23874	111	26	°	°	NOUN
brj-23874	111	27	c	c	NOUN
brj-23874	111	28	.	.	PUNCT
brj-23874	112	1	the	the	DET
brj-23874	112	2	concentration	concentration	NOUN
brj-23874	112	3	range	range	NOUN
brj-23874	112	4	was	be	AUX
brj-23874	112	5	chosen	choose	VERB
brj-23874	112	6	by	by	ADP
brj-23874	112	7	prior	prior	ADJ
brj-23874	112	8	research	research	NOUN
brj-23874	112	9	that	that	PRON
brj-23874	112	10	examined	examine	VERB
brj-23874	112	11	comparable	comparable	ADJ
brj-23874	112	12	experimental	experimental	ADJ
brj-23874	112	13	configurations	configuration	NOUN
brj-23874	112	14	utilizing	utilize	VERB
brj-23874	112	15	water	water	NOUN
brj-23874	112	16	extracts	extract	NOUN
brj-23874	112	17	and	and	CCONJ
brj-23874	112	18	fixed	fix	VERB
brj-23874	112	19	oils	oil	NOUN
brj-23874	112	20	derived	derive	VERB
brj-23874	112	21	from	from	ADP
brj-23874	112	22	c.	c.	PROPN
brj-23874	112	23	coccineum	coccineum	PROPN
brj-23874	112	24	(	(	PUNCT
brj-23874	112	25	rosa	rosa	PROPN
brj-23874	112	26	et	et	PROPN
brj-23874	112	27	al	al	PROPN
brj-23874	112	28	.	.	PROPN
brj-23874	112	29	2012	2012	NUM
brj-23874	112	30	)	)	PUNCT
brj-23874	112	31	.	.	PUNCT
brj-23874	113	1	the	the	DET
brj-23874	113	2	extract	extract	NOUN
brj-23874	113	3	did	do	AUX
brj-23874	113	4	not	not	PART
brj-23874	113	5	significantly	significantly	ADV
brj-23874	113	6	harm	harm	VERB
brj-23874	113	7	the	the	DET
brj-23874	113	8	melanoma	melanoma	NOUN
brj-23874	113	9	cells	cell	NOUN
brj-23874	113	10	,	,	PUNCT
brj-23874	113	11	even	even	ADV
brj-23874	113	12	at	at	ADP
brj-23874	113	13	higher	high	ADJ
brj-23874	113	14	doses	dose	NOUN
brj-23874	113	15	(	(	PUNCT
brj-23874	113	16	150	150	NUM
brj-23874	113	17	µg	µg	NOUN
brj-23874	113	18	/	/	SYM
brj-23874	113	19	ml	ml	NOUN
brj-23874	113	20	)	)	PUNCT
brj-23874	113	21	,	,	PUNCT
brj-23874	113	22	as	as	SCONJ
brj-23874	113	23	indicated	indicate	VERB
brj-23874	113	24	in	in	ADP
brj-23874	113	25	fig	fig	NOUN
brj-23874	113	26	.	.	PUNCT
brj-23874	114	1	1	1	X
brj-23874	114	2	.	.	PUNCT
brj-23874	114	3	the	the	DET
brj-23874	114	4	present	present	ADJ
brj-23874	114	5	results	result	NOUN
brj-23874	114	6	contrast	contrast	VERB
brj-23874	114	7	with	with	ADP
brj-23874	114	8	those	those	PRON
brj-23874	114	9	of	of	ADP
brj-23874	114	10	maisetta	maisetta	PROPN
brj-23874	114	11	et	et	PROPN
brj-23874	114	12	al	al	PROPN
brj-23874	114	13	.	.	PROPN
brj-23874	115	1	(	(	PUNCT
brj-23874	115	2	2019	2019	NUM
brj-23874	115	3	,	,	PUNCT
brj-23874	115	4	who	who	PRON
brj-23874	115	5	demonstrated	demonstrate	VERB
brj-23874	115	6	that	that	SCONJ
brj-23874	115	7	the	the	DET
brj-23874	115	8	extracts	extract	NOUN
brj-23874	115	9	of	of	ADP
brj-23874	115	10	greek	greek	NOUN
brj-23874	115	11	cytinus	cytinus	NOUN
brj-23874	115	12	exhibited	exhibit	VERB
brj-23874	115	13	cytotoxic	cytotoxic	ADJ
brj-23874	115	14	activity	activity	NOUN
brj-23874	115	15	against	against	ADP
brj-23874	115	16	a	a	DET
brj-23874	115	17	variety	variety	NOUN
brj-23874	115	18	of	of	ADP
brj-23874	115	19	cancer	cancer	NOUN
brj-23874	115	20	cell	cell	NOUN
brj-23874	115	21	lines	line	NOUN
brj-23874	115	22	.	.	PUNCT
brj-23874	116	1	peer	peer	NOUN
brj-23874	116	2	-	-	PUNCT
brj-23874	116	3	reviewed	review	VERB
brj-23874	116	4	article	article	NOUN
brj-23874	116	5	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	116	6	zhu	zhu	PROPN
brj-23874	116	7	et	et	PROPN
brj-23874	116	8	al	al	PROPN
brj-23874	116	9	.	.	PROPN
brj-23874	117	1	(	(	PUNCT
brj-23874	117	2	2026	2026	NUM
brj-23874	117	3	)	)	PUNCT
brj-23874	117	4	.	.	PUNCT
brj-23874	118	1	“	"	PUNCT
brj-23874	118	2	pain	pain	NOUN
brj-23874	118	3	control	control	NOUN
brj-23874	118	4	with	with	ADP
brj-23874	118	5	seed	seed	NOUN
brj-23874	118	6	extract	extract	NOUN
brj-23874	118	7	,	,	PUNCT
brj-23874	118	8	”	"	PUNCT
brj-23874	118	9	bioresources	bioresource	NOUN
brj-23874	118	10	21(1	21(1	NUM
brj-23874	118	11	)	)	PUNCT
brj-23874	118	12	,	,	PUNCT
brj-23874	118	13	116	116	NUM
brj-23874	118	14	-	-	SYM
brj-23874	118	15	127	127	NUM
brj-23874	118	16	.	.	PUNCT
brj-23874	119	1	121	121	NUM
brj-23874	119	2	fig	fig	NOUN
brj-23874	119	3	.	.	PUNCT
brj-23874	120	1	1	1	X
brj-23874	120	2	.	.	X
brj-23874	120	3	viability	viability	NOUN
brj-23874	120	4	(	(	PUNCT
brj-23874	120	5	expressed	express	VERB
brj-23874	120	6	as	as	ADP
brj-23874	120	7	%	%	NOUN
brj-23874	120	8	of	of	ADP
brj-23874	120	9	the	the	DET
brj-23874	120	10	control	control	NOUN
brj-23874	120	11	)	)	PUNCT
brj-23874	120	12	induced	induce	VERB
brj-23874	120	13	by	by	ADP
brj-23874	120	14	24	24	NUM
brj-23874	120	15	h	h	NOUN
brj-23874	120	16	incubation	incubation	NOUN
brj-23874	120	17	with	with	ADP
brj-23874	120	18	c.	c.	PROPN
brj-23874	120	19	colocynthis	colocynthis	PROPN
brj-23874	120	20	aqueous	aqueous	ADJ
brj-23874	120	21	extracts	extract	NOUN
brj-23874	120	22	in	in	ADP
brj-23874	120	23	melanoma	melanoma	NOUN
brj-23874	120	24	b16f10	b16f10	ADJ
brj-23874	120	25	cells	cell	NOUN
brj-23874	120	26	.	.	PUNCT
brj-23874	121	1	data	datum	NOUN
brj-23874	121	2	are	be	AUX
brj-23874	121	3	the	the	DET
brj-23874	121	4	means	mean	NOUN
brj-23874	121	5	±	±	NUM
brj-23874	121	6	standard	standard	ADJ
brj-23874	121	7	deviations	deviation	NOUN
brj-23874	121	8	of	of	ADP
brj-23874	121	9	three	three	NUM
brj-23874	121	10	independent	independent	ADJ
brj-23874	121	11	experiments	experiment	NOUN
brj-23874	121	12	involving	involve	VERB
brj-23874	121	13	triplicate	triplicate	NOUN
brj-23874	121	14	analyses	analysis	NOUN
brj-23874	121	15	for	for	ADP
brj-23874	121	16	each	each	DET
brj-23874	121	17	sample	sample	NOUN
brj-23874	121	18	.	.	PUNCT
brj-23874	122	1	live	live	ADJ
brj-23874	122	2	/	/	SYM
brj-23874	122	3	dead	dead	ADJ
brj-23874	122	4	staining	stain	VERB
brj-23874	122	5	both	both	DET
brj-23874	122	6	untreated	untreate	VERB
brj-23874	122	7	b16f10	b16f10	ADJ
brj-23874	122	8	cells	cell	NOUN
brj-23874	122	9	and	and	CCONJ
brj-23874	122	10	those	those	PRON
brj-23874	122	11	treated	treat	VERB
brj-23874	122	12	with	with	ADP
brj-23874	122	13	a	a	DET
brj-23874	122	14	concentration	concentration	NOUN
brj-23874	122	15	of	of	ADP
brj-23874	122	16	100	100	NUM
brj-23874	122	17	µg	µg	NOUN
brj-23874	122	18	/	/	SYM
brj-23874	122	19	ml	ml	NOUN
brj-23874	122	20	of	of	ADP
brj-23874	122	21	c.	c.	PROPN
brj-23874	122	22	colocynthis	colocynthis	PROPN
brj-23874	122	23	plant	plant	NOUN
brj-23874	122	24	extract	extract	NOUN
brj-23874	122	25	were	be	AUX
brj-23874	122	26	subjected	subject	VERB
brj-23874	122	27	to	to	ADP
brj-23874	122	28	the	the	DET
brj-23874	122	29	live	live	ADJ
brj-23874	122	30	/	/	SYM
brj-23874	122	31	dead	dead	ADJ
brj-23874	122	32	cell	cell	NOUN
brj-23874	122	33	test	test	NOUN
brj-23874	122	34	.	.	PUNCT
brj-23874	123	1	as	as	SCONJ
brj-23874	123	2	shown	show	VERB
brj-23874	123	3	in	in	ADP
brj-23874	123	4	fig	fig	NOUN
brj-23874	123	5	.	.	PUNCT
brj-23874	124	1	2a	2a	NUM
brj-23874	124	2	and	and	CCONJ
brj-23874	124	3	2b	2b	NOUN
brj-23874	124	4	,	,	PUNCT
brj-23874	124	5	treatment	treatment	NOUN
brj-23874	124	6	with	with	ADP
brj-23874	124	7	the	the	DET
brj-23874	124	8	extract	extract	NOUN
brj-23874	124	9	caused	cause	VERB
brj-23874	124	10	a	a	DET
brj-23874	124	11	significant	significant	ADJ
brj-23874	124	12	amount	amount	NOUN
brj-23874	124	13	of	of	ADP
brj-23874	124	14	cell	cell	NOUN
brj-23874	124	15	death	death	NOUN
brj-23874	124	16	in	in	ADP
brj-23874	124	17	comparison	comparison	NOUN
brj-23874	124	18	to	to	ADP
brj-23874	124	19	the	the	DET
brj-23874	124	20	untreated	untreated	ADJ
brj-23874	124	21	cells	cell	NOUN
brj-23874	124	22	.	.	PUNCT
brj-23874	125	1	significant	significant	ADJ
brj-23874	125	2	morphological	morphological	ADJ
brj-23874	125	3	alterations	alteration	NOUN
brj-23874	125	4	caused	cause	VERB
brj-23874	125	5	by	by	ADP
brj-23874	125	6	the	the	DET
brj-23874	125	7	plant	plant	NOUN
brj-23874	125	8	extract	extract	NOUN
brj-23874	125	9	resulted	result	VERB
brj-23874	125	10	in	in	ADP
brj-23874	125	11	diminished	diminished	ADJ
brj-23874	125	12	confluency	confluency	NOUN
brj-23874	125	13	and	and	CCONJ
brj-23874	125	14	widespread	widespread	ADJ
brj-23874	125	15	propidium	propidium	NOUN
brj-23874	125	16	iodide	iodide	NOUN
brj-23874	125	17	(	(	PUNCT
brj-23874	125	18	pi	pi	NOUN
brj-23874	125	19	)	)	PUNCT
brj-23874	125	20	staining	stain	VERB
brj-23874	125	21	.	.	PUNCT
brj-23874	126	1	these	these	DET
brj-23874	126	2	results	result	NOUN
brj-23874	126	3	show	show	VERB
brj-23874	126	4	that	that	SCONJ
brj-23874	126	5	c.	c.	PROPN
brj-23874	126	6	colocynthis	colocynthis	PROPN
brj-23874	126	7	is	be	AUX
brj-23874	126	8	very	very	ADV
brj-23874	126	9	hazardous	hazardous	ADJ
brj-23874	126	10	to	to	ADP
brj-23874	126	11	b16f10	b16f10	ADJ
brj-23874	126	12	cell	cell	NOUN
brj-23874	126	13	lines	line	NOUN
brj-23874	126	14	.	.	PUNCT
brj-23874	127	1	using	use	VERB
brj-23874	127	2	images	image	NOUN
brj-23874	127	3	from	from	ADP
brj-23874	127	4	clsm	clsm	NOUN
brj-23874	127	5	,	,	PUNCT
brj-23874	127	6	the	the	DET
brj-23874	127	7	reduced	reduce	VERB
brj-23874	127	8	cell	cell	NOUN
brj-23874	127	9	viability	viability	NOUN
brj-23874	127	10	and	and	CCONJ
brj-23874	127	11	enhanced	enhance	VERB
brj-23874	127	12	cytotoxicity	cytotoxicity	NOUN
brj-23874	127	13	were	be	AUX
brj-23874	127	14	verified	verify	VERB
brj-23874	127	15	.	.	PUNCT
brj-23874	128	1	fig	fig	NOUN
brj-23874	128	2	.	.	PUNCT
brj-23874	129	1	2	2	X
brj-23874	129	2	.	.	X
brj-23874	129	3	live	live	ADJ
brj-23874	129	4	/	/	SYM
brj-23874	129	5	dead	dead	ADJ
brj-23874	129	6	assay	assay	NOUN
brj-23874	129	7	of	of	ADP
brj-23874	129	8	b16f10	b16f10	ADJ
brj-23874	129	9	cells	cell	NOUN
brj-23874	129	10	(	(	PUNCT
brj-23874	129	11	a	a	X
brj-23874	129	12	)	)	PUNCT
brj-23874	129	13	untreated	untreated	ADJ
brj-23874	129	14	and	and	CCONJ
brj-23874	129	15	(	(	PUNCT
brj-23874	129	16	b	b	NOUN
brj-23874	129	17	)	)	PUNCT
brj-23874	129	18	treated	treat	VERB
brj-23874	129	19	with	with	ADP
brj-23874	129	20	plant	plant	NOUN
brj-23874	129	21	extract	extract	NOUN
brj-23874	129	22	assessment	assessment	NOUN
brj-23874	129	23	of	of	ADP
brj-23874	129	24	anti	anti	ADJ
brj-23874	129	25	-	-	ADJ
brj-23874	129	26	microbial	microbial	ADJ
brj-23874	129	27	activity	activity	NOUN
brj-23874	129	28	table	table	NOUN
brj-23874	129	29	1	1	NUM
brj-23874	129	30	provides	provide	VERB
brj-23874	129	31	a	a	DET
brj-23874	129	32	comprehensive	comprehensive	ADJ
brj-23874	129	33	overview	overview	NOUN
brj-23874	129	34	of	of	ADP
brj-23874	129	35	c.	c.	PROPN
brj-23874	129	36	colocynthis	colocynthis	PROPN
brj-23874	129	37	extract	extract	VERB
brj-23874	129	38	’s	’s	PART
brj-23874	129	39	antibacterial	antibacterial	ADJ
brj-23874	129	40	activities	activity	NOUN
brj-23874	129	41	.	.	PUNCT
brj-23874	130	1	it	it	PRON
brj-23874	130	2	is	be	AUX
brj-23874	130	3	worth	worth	ADJ
brj-23874	130	4	mentioning	mention	VERB
brj-23874	130	5	that	that	SCONJ
brj-23874	130	6	all	all	DET
brj-23874	130	7	the	the	DET
brj-23874	130	8	gram	gram	NOUN
brj-23874	130	9	-	-	PUNCT
brj-23874	130	10	positive	positive	ADJ
brj-23874	130	11	bacteria	bacteria	NOUN
brj-23874	130	12	that	that	PRON
brj-23874	130	13	were	be	AUX
brj-23874	130	14	studied	study	VERB
brj-23874	130	15	were	be	AUX
brj-23874	130	16	effectively	effectively	ADV
brj-23874	130	17	targeted	target	VERB
brj-23874	130	18	by	by	ADP
brj-23874	130	19	the	the	DET
brj-23874	130	20	c.	c.	PROPN
brj-23874	130	21	colocynthis	colocynthis	PROPN
brj-23874	130	22	extract	extract	NOUN
brj-23874	130	23	.	.	PUNCT
brj-23874	131	1	more	more	ADV
brj-23874	131	2	specifically	specifically	ADV
brj-23874	131	3	,	,	PUNCT
brj-23874	131	4	for	for	ADP
brj-23874	131	5	every	every	DET
brj-23874	131	6	disc	disc	NOUN
brj-23874	131	7	treated	treat	VERB
brj-23874	131	8	with	with	ADP
brj-23874	131	9	0.5	0.5	NUM
brj-23874	131	10	mg	mg	NOUN
brj-23874	131	11	of	of	ADP
brj-23874	131	12	the	the	DET
brj-23874	131	13	extract	extract	NOUN
brj-23874	131	14	,	,	PUNCT
brj-23874	131	15	inhibitory	inhibitory	ADJ
brj-23874	131	16	zones	zone	NOUN
brj-23874	131	17	surpassed	surpass	VERB
brj-23874	131	18	10	10	NUM
brj-23874	131	19	mm	mm	NOUN
brj-23874	131	20	.	.	PUNCT
brj-23874	132	1	research	research	NOUN
brj-23874	132	2	says	say	VERB
brj-23874	132	3	that	that	SCONJ
brj-23874	132	4	the	the	DET
brj-23874	132	5	inhibition	inhibition	NOUN
brj-23874	132	6	zones	zone	NOUN
brj-23874	132	7	bigger	big	ADJ
brj-23874	132	8	than	than	ADP
brj-23874	132	9	9	9	NUM
brj-23874	132	10	mm	mm	NOUN
brj-23874	132	11	show	show	VERB
brj-23874	132	12	antibacterial	antibacterial	ADJ
brj-23874	132	13	activity	activity	NOUN
brj-23874	132	14	and	and	CCONJ
brj-23874	132	15	smaller	small	ADJ
brj-23874	132	16	zones	zone	NOUN
brj-23874	132	17	suggest	suggest	VERB
brj-23874	132	18	ineffectiveness	ineffectiveness	NOUN
brj-23874	132	19	(	(	PUNCT
brj-23874	132	20	olmedo	olmedo	PROPN
brj-23874	132	21	et	et	PROPN
brj-23874	132	22	al	al	PROPN
brj-23874	132	23	2024	2024	NUM
brj-23874	132	24	)	)	PUNCT
brj-23874	132	25	.	.	PUNCT
brj-23874	133	1	peer	peer	NOUN
brj-23874	133	2	-	-	PUNCT
brj-23874	133	3	reviewed	review	VERB
brj-23874	133	4	article	article	NOUN
brj-23874	133	5	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	133	6	zhu	zhu	PROPN
brj-23874	133	7	et	et	PROPN
brj-23874	133	8	al	al	PROPN
brj-23874	133	9	.	.	PROPN
brj-23874	134	1	(	(	PUNCT
brj-23874	134	2	2026	2026	NUM
brj-23874	134	3	)	)	PUNCT
brj-23874	134	4	.	.	PUNCT
brj-23874	135	1	“	"	PUNCT
brj-23874	135	2	pain	pain	NOUN
brj-23874	135	3	control	control	NOUN
brj-23874	135	4	with	with	ADP
brj-23874	135	5	seed	seed	NOUN
brj-23874	135	6	extract	extract	NOUN
brj-23874	135	7	,	,	PUNCT
brj-23874	135	8	”	"	PUNCT
brj-23874	135	9	bioresources	bioresource	NOUN
brj-23874	135	10	21(1	21(1	NUM
brj-23874	135	11	)	)	PUNCT
brj-23874	135	12	,	,	PUNCT
brj-23874	135	13	116	116	NUM
brj-23874	135	14	-	-	SYM
brj-23874	135	15	127	127	NUM
brj-23874	135	16	.	.	PUNCT
brj-23874	136	1	122	122	NUM
brj-23874	136	2	table	table	NOUN
brj-23874	136	3	1	1	NUM
brj-23874	136	4	.	.	PUNCT
brj-23874	136	5	anti	anti	ADJ
brj-23874	136	6	-	-	ADJ
brj-23874	136	7	microbial	microbial	ADJ
brj-23874	136	8	activity	activity	NOUN
brj-23874	136	9	of	of	ADP
brj-23874	136	10	c.	c.	PROPN
brj-23874	136	11	colocynthis	colocynthis	PROPN
brj-23874	136	12	extract	extract	VERB
brj-23874	136	13	using	use	VERB
brj-23874	136	14	disc	disc	NOUN
brj-23874	136	15	diffusion	diffusion	NOUN
brj-23874	136	16	technique	technique	NOUN
brj-23874	136	17	bacterial	bacterial	ADJ
brj-23874	136	18	strains	strain	NOUN
brj-23874	136	19	aqueous	aqueous	ADJ
brj-23874	136	20	extract	extract	NOUN
brj-23874	136	21	0.5	0.5	NUM
brj-23874	136	22	mg	mg	NOUN
brj-23874	136	23	/	/	SYM
brj-23874	136	24	disc	disc	NOUN
brj-23874	136	25	(	(	PUNCT
brj-23874	136	26	mm	mm	NOUN
brj-23874	136	27	)	)	PUNCT
brj-23874	136	28	antibiotic	antibiotic	ADJ
brj-23874	136	29	control	control	NOUN
brj-23874	136	30	gram	gram	NOUN
brj-23874	136	31	negative	negative	ADJ
brj-23874	136	32	escherichia	escherichia	NOUN
brj-23874	136	33	coli	coli	NOUN
brj-23874	136	34	(	(	PUNCT
brj-23874	136	35	dsm1103	dsm1103	ADJ
brj-23874	136	36	)	)	PUNCT
brj-23874	136	37	0.0	0.0	NUM
brj-23874	136	38	±	±	NUM
brj-23874	136	39	0.0	0.0	NUM
brj-23874	136	40	amp	amp	NOUN
brj-23874	136	41	16.7	16.7	NUM
brj-23874	136	42	±	±	NUM
brj-23874	136	43	0.5	0.5	NUM
brj-23874	136	44	pseudomonas	pseudomona	NOUN
brj-23874	136	45	aeruginosa	aeruginosa	NOUN
brj-23874	136	46	(	(	PUNCT
brj-23874	136	47	dsm117	dsm117	PROPN
brj-23874	136	48	)	)	PUNCT
brj-23874	136	49	0.0	0.0	NUM
brj-23874	136	50	±	±	NUM
brj-23874	136	51	0.0	0.0	NUM
brj-23874	136	52	amp	amp	PROPN
brj-23874	136	53	12.5	12.5	NUM
brj-23874	136	54	±	±	NUM
brj-23874	136	55	0.7	0.7	NUM
brj-23874	136	56	gram	gram	NOUN
brj-23874	136	57	positive	positive	ADJ
brj-23874	136	58	staphylococcus	staphylococcus	NOUN
brj-23874	136	59	aureus	aureus	NOUN
brj-23874	136	60	(	(	PUNCT
brj-23874	136	61	dsm1104	dsm1104	NOUN
brj-23874	136	62	)	)	PUNCT
brj-23874	136	63	10.0	10.0	NUM
brj-23874	136	64	±	±	NUM
brj-23874	136	65	1.6	1.6	NUM
brj-23874	136	66	amp	amp	PROPN
brj-23874	136	67	1.2	1.2	NUM
brj-23874	136	68	±	±	NUM
brj-23874	136	69	1.05	1.05	NUM
brj-23874	136	70	enterococcus	enterococcus	NOUN
brj-23874	136	71	faecalis	faecali	NOUN
brj-23874	136	72	(	(	PUNCT
brj-23874	136	73	dsm2570	dsm2570	NOUN
brj-23874	136	74	)	)	PUNCT
brj-23874	136	75	8.0	8.0	NUM
brj-23874	136	76	±	±	NUM
brj-23874	136	77	3.1	3.1	NUM
brj-23874	136	78	amp	amp	NOUN
brj-23874	136	79	22.1	22.1	NUM
brj-23874	136	80	±	±	NUM
brj-23874	136	81	0.5	0.5	NUM
brj-23874	136	82	under	under	ADP
brj-23874	136	83	the	the	DET
brj-23874	136	84	same	same	ADJ
brj-23874	136	85	experimental	experimental	ADJ
brj-23874	136	86	conditions	condition	NOUN
brj-23874	136	87	,	,	PUNCT
brj-23874	136	88	the	the	DET
brj-23874	136	89	c.	c.	PROPN
brj-23874	136	90	colocynthis	colocynthis	PROPN
brj-23874	136	91	extract	extract	NOUN
brj-23874	136	92	demonstrated	demonstrate	VERB
brj-23874	136	93	a	a	DET
brj-23874	136	94	wider	wide	ADJ
brj-23874	136	95	range	range	NOUN
brj-23874	136	96	of	of	ADP
brj-23874	136	97	action	action	NOUN
brj-23874	136	98	but	but	CCONJ
brj-23874	136	99	was	be	AUX
brj-23874	136	100	not	not	PART
brj-23874	136	101	as	as	ADV
brj-23874	136	102	powerful	powerful	ADJ
brj-23874	136	103	as	as	ADP
brj-23874	136	104	the	the	DET
brj-23874	136	105	conventional	conventional	ADJ
brj-23874	136	106	antibiotic	antibiotic	ADJ
brj-23874	136	107	ampicillin	ampicillin	NOUN
brj-23874	136	108	.	.	PUNCT
brj-23874	137	1	it	it	PRON
brj-23874	137	2	is	be	AUX
brj-23874	137	3	worth	worth	ADJ
brj-23874	137	4	mentioning	mention	VERB
brj-23874	137	5	that	that	SCONJ
brj-23874	137	6	ampicillin	ampicillin	PROPN
brj-23874	137	7	had	have	VERB
brj-23874	137	8	no	no	DET
brj-23874	137	9	effect	effect	NOUN
brj-23874	137	10	on	on	ADP
brj-23874	137	11	mrsa	mrsa	NOUN
brj-23874	137	12	s.	s.	PROPN
brj-23874	137	13	aureus	aureus	PROPN
brj-23874	137	14	.	.	PUNCT
brj-23874	138	1	additionally	additionally	ADV
brj-23874	138	2	,	,	PUNCT
brj-23874	138	3	the	the	DET
brj-23874	138	4	c.	c.	PROPN
brj-23874	138	5	colocynthis	colocynthis	PROPN
brj-23874	138	6	aqueous	aqueous	ADJ
brj-23874	138	7	extract	extract	NOUN
brj-23874	138	8	showed	show	VERB
brj-23874	138	9	efficacy	efficacy	NOUN
brj-23874	138	10	against	against	ADP
brj-23874	138	11	bacteria	bacteria	NOUN
brj-23874	138	12	that	that	PRON
brj-23874	138	13	are	be	AUX
brj-23874	138	14	gram	gram	NOUN
brj-23874	138	15	-	-	PUNCT
brj-23874	138	16	negative	negative	ADJ
brj-23874	138	17	as	as	ADV
brj-23874	138	18	well	well	ADV
brj-23874	138	19	(	(	PUNCT
brj-23874	138	20	table	table	NOUN
brj-23874	138	21	1	1	NUM
brj-23874	138	22	)	)	PUNCT
brj-23874	138	23	.	.	PUNCT
brj-23874	139	1	evaluation	evaluation	NOUN
brj-23874	139	2	of	of	ADP
brj-23874	139	3	analgesic	analgesic	ADJ
brj-23874	139	4	activity	activity	NOUN
brj-23874	139	5	table	table	NOUN
brj-23874	139	6	2	2	NUM
brj-23874	139	7	illustrates	illustrate	VERB
brj-23874	139	8	that	that	SCONJ
brj-23874	139	9	the	the	DET
brj-23874	139	10	cc	cc	PROPN
brj-23874	139	11	150	150	NUM
brj-23874	139	12	and	and	CCONJ
brj-23874	139	13	cc	cc	X
brj-23874	139	14	200	200	NUM
brj-23874	139	15	dose	dose	NOUN
brj-23874	139	16	groups	group	NOUN
brj-23874	139	17	significantly	significantly	ADV
brj-23874	139	18	reduced	reduce	VERB
brj-23874	139	19	pain	pain	NOUN
brj-23874	139	20	when	when	SCONJ
brj-23874	139	21	compared	compare	VERB
brj-23874	139	22	to	to	ADP
brj-23874	139	23	the	the	DET
brj-23874	139	24	control	control	NOUN
brj-23874	139	25	and	and	CCONJ
brj-23874	139	26	cc	cc	NOUN
brj-23874	139	27	100	100	NUM
brj-23874	139	28	groups	group	NOUN
brj-23874	139	29	.	.	PUNCT
brj-23874	140	1	the	the	DET
brj-23874	140	2	mo10	mo10	PROPN
brj-23874	140	3	group	group	NOUN
brj-23874	140	4	showed	show	VERB
brj-23874	140	5	a	a	DET
brj-23874	140	6	similar	similar	ADJ
brj-23874	140	7	pattern	pattern	NOUN
brj-23874	140	8	of	of	ADP
brj-23874	140	9	extended	extended	ADJ
brj-23874	140	10	pain	pain	NOUN
brj-23874	140	11	response	response	NOUN
brj-23874	140	12	time	time	NOUN
brj-23874	140	13	.	.	PUNCT
brj-23874	141	1	furthermore	furthermore	ADV
brj-23874	141	2	,	,	PUNCT
brj-23874	141	3	during	during	ADP
brj-23874	141	4	the	the	DET
brj-23874	141	5	study	study	NOUN
brj-23874	141	6	,	,	PUNCT
brj-23874	141	7	the	the	DET
brj-23874	141	8	cc	cc	PROPN
brj-23874	141	9	200	200	NUM
brj-23874	141	10	group	group	NOUN
brj-23874	141	11	’s	’s	PART
brj-23874	141	12	effectiveness	effectiveness	NOUN
brj-23874	141	13	at	at	ADP
brj-23874	141	14	alleviating	alleviate	VERB
brj-23874	141	15	pain	pain	NOUN
brj-23874	141	16	was	be	AUX
brj-23874	141	17	comparable	comparable	ADJ
brj-23874	141	18	to	to	ADP
brj-23874	141	19	that	that	PRON
brj-23874	141	20	of	of	ADP
brj-23874	141	21	the	the	DET
brj-23874	141	22	mo10	mo10	PROPN
brj-23874	141	23	group	group	NOUN
brj-23874	141	24	.	.	PUNCT
brj-23874	142	1	surprisingly	surprisingly	ADV
brj-23874	142	2	,	,	PUNCT
brj-23874	142	3	the	the	DET
brj-23874	142	4	maximum	maximum	ADJ
brj-23874	142	5	analgesic	analgesic	ADJ
brj-23874	142	6	response	response	NOUN
brj-23874	142	7	was	be	AUX
brj-23874	142	8	measured	measure	VERB
brj-23874	142	9	after	after	ADP
brj-23874	142	10	120	120	NUM
brj-23874	142	11	min	min	NOUN
brj-23874	142	12	,	,	PUNCT
brj-23874	142	13	and	and	CCONJ
brj-23874	142	14	the	the	DET
brj-23874	142	15	cc	cc	PROPN
brj-23874	142	16	150	150	NUM
brj-23874	142	17	,	,	PUNCT
brj-23874	142	18	cc	cc	VERB
brj-23874	142	19	200	200	NUM
brj-23874	142	20	,	,	PUNCT
brj-23874	142	21	and	and	CCONJ
brj-23874	142	22	mo	mo	PROPN
brj-23874	142	23	10	10	NUM
brj-23874	142	24	groups	group	NOUN
brj-23874	142	25	had	have	VERB
brj-23874	142	26	pain	pain	NOUN
brj-23874	142	27	inhibition	inhibition	NOUN
brj-23874	142	28	percentages	percentage	NOUN
brj-23874	142	29	of	of	ADP
brj-23874	142	30	74	74	NUM
brj-23874	142	31	%	%	NOUN
brj-23874	142	32	,	,	PUNCT
brj-23874	142	33	85	85	NUM
brj-23874	142	34	%	%	NOUN
brj-23874	142	35	,	,	PUNCT
brj-23874	142	36	and	and	CCONJ
brj-23874	142	37	80	80	NUM
brj-23874	142	38	%	%	NOUN
brj-23874	142	39	,	,	PUNCT
brj-23874	142	40	respectively	respectively	ADV
brj-23874	142	41	.	.	PUNCT
brj-23874	143	1	cc	cc	AUX
brj-23874	143	2	200	200	NUM
brj-23874	143	3	consistently	consistently	ADV
brj-23874	143	4	exceeded	exceed	VERB
brj-23874	143	5	dw	dw	PROPN
brj-23874	143	6	,	,	PUNCT
brj-23874	143	7	cc	cc	PROPN
brj-23874	143	8	100	100	NUM
brj-23874	143	9	,	,	PUNCT
brj-23874	143	10	and	and	CCONJ
brj-23874	143	11	cc	cc	X
brj-23874	143	12	150	150	NUM
brj-23874	143	13	groups	group	NOUN
brj-23874	143	14	in	in	ADP
brj-23874	143	15	terms	term	NOUN
brj-23874	143	16	of	of	ADP
brj-23874	143	17	pain	pain	NOUN
brj-23874	143	18	inhibition	inhibition	NOUN
brj-23874	143	19	percentage	percentage	NOUN
brj-23874	143	20	for	for	ADP
brj-23874	143	21	the	the	DET
brj-23874	143	22	course	course	NOUN
brj-23874	143	23	of	of	ADP
brj-23874	143	24	the	the	DET
brj-23874	143	25	trial	trial	NOUN
brj-23874	143	26	,	,	PUNCT
brj-23874	143	27	outperforming	outperform	VERB
brj-23874	143	28	all	all	DET
brj-23874	143	29	tested	test	VERB
brj-23874	143	30	extract	extract	NOUN
brj-23874	143	31	doses	dose	NOUN
brj-23874	143	32	.	.	PUNCT
brj-23874	144	1	however	however	ADV
brj-23874	144	2	,	,	PUNCT
brj-23874	144	3	cc	cc	PROPN
brj-23874	144	4	200	200	NUM
brj-23874	144	5	demonstrated	demonstrate	VERB
brj-23874	144	6	a	a	DET
brj-23874	144	7	lower	low	ADJ
brj-23874	144	8	pain	pain	NOUN
brj-23874	144	9	inhibition	inhibition	NOUN
brj-23874	144	10	%	%	NOUN
brj-23874	144	11	than	than	ADP
brj-23874	144	12	mo	mo	PROPN
brj-23874	144	13	10	10	NUM
brj-23874	144	14	until	until	ADP
brj-23874	144	15	the	the	DET
brj-23874	144	16	90	90	NUM
brj-23874	144	17	-	-	PUNCT
brj-23874	144	18	min	min	NOUN
brj-23874	144	19	mark	mark	NOUN
brj-23874	144	20	,	,	PUNCT
brj-23874	144	21	at	at	ADP
brj-23874	144	22	which	which	DET
brj-23874	144	23	point	point	NOUN
brj-23874	144	24	its	its	PRON
brj-23874	144	25	effectiveness	effectiveness	NOUN
brj-23874	144	26	exceeded	exceed	VERB
brj-23874	144	27	that	that	PRON
brj-23874	144	28	of	of	ADP
brj-23874	144	29	the	the	DET
brj-23874	144	30	mo	mo	PROPN
brj-23874	144	31	10	10	NUM
brj-23874	144	32	group	group	NOUN
brj-23874	144	33	.	.	PUNCT
brj-23874	145	1	the	the	DET
brj-23874	145	2	peak	peak	ADJ
brj-23874	145	3	analgesic	analgesic	ADJ
brj-23874	145	4	effects	effect	NOUN
brj-23874	145	5	of	of	ADP
brj-23874	145	6	all	all	DET
brj-23874	145	7	experimental	experimental	ADJ
brj-23874	145	8	groups	group	NOUN
brj-23874	145	9	were	be	AUX
brj-23874	145	10	observed	observe	VERB
brj-23874	145	11	at	at	ADP
brj-23874	145	12	120	120	NUM
brj-23874	145	13	minutes	minute	NOUN
brj-23874	145	14	in	in	ADP
brj-23874	145	15	the	the	DET
brj-23874	145	16	hot	hot	ADJ
brj-23874	145	17	plate	plate	NOUN
brj-23874	145	18	test	test	NOUN
brj-23874	145	19	.	.	PUNCT
brj-23874	146	1	the	the	DET
brj-23874	146	2	duration	duration	NOUN
brj-23874	146	3	of	of	ADP
brj-23874	146	4	this	this	DET
brj-23874	146	5	effect	effect	NOUN
brj-23874	146	6	may	may	AUX
brj-23874	146	7	be	be	AUX
brj-23874	146	8	attributed	attribute	VERB
brj-23874	146	9	to	to	ADP
brj-23874	146	10	the	the	DET
brj-23874	146	11	drug	drug	NOUN
brj-23874	146	12	’s	’s	PART
brj-23874	146	13	time	time	NOUN
brj-23874	146	14	to	to	PART
brj-23874	146	15	penetrate	penetrate	VERB
brj-23874	146	16	the	the	DET
brj-23874	146	17	central	central	ADJ
brj-23874	146	18	compartment	compartment	NOUN
brj-23874	146	19	and	and	CCONJ
brj-23874	146	20	reach	reach	VERB
brj-23874	146	21	the	the	DET
brj-23874	146	22	target	target	NOUN
brj-23874	146	23	site	site	NOUN
brj-23874	146	24	(	(	PUNCT
brj-23874	146	25	gordon	gordon	PROPN
brj-23874	146	26	et	et	PROPN
brj-23874	146	27	al	al	PROPN
brj-23874	146	28	2016	2016	NUM
brj-23874	146	29	)	)	PUNCT
brj-23874	146	30	.	.	PUNCT
brj-23874	147	1	cc100	cc100	PROPN
brj-23874	147	2	did	do	AUX
brj-23874	147	3	not	not	PART
brj-23874	147	4	exhibit	exhibit	VERB
brj-23874	147	5	any	any	DET
brj-23874	147	6	significant	significant	ADJ
brj-23874	147	7	effects	effect	NOUN
brj-23874	147	8	among	among	ADP
brj-23874	147	9	the	the	DET
brj-23874	147	10	tested	test	VERB
brj-23874	147	11	groups	group	NOUN
brj-23874	147	12	.	.	PUNCT
brj-23874	148	1	however	however	ADV
brj-23874	148	2	,	,	PUNCT
brj-23874	148	3	cc150	cc150	PROPN
brj-23874	148	4	and	and	CCONJ
brj-23874	148	5	cc200	cc200	PROPN
brj-23874	148	6	exhibited	exhibit	VERB
brj-23874	148	7	significant	significant	ADJ
brj-23874	148	8	analgesic	analgesic	ADJ
brj-23874	148	9	activity	activity	NOUN
brj-23874	148	10	,	,	PUNCT
brj-23874	148	11	with	with	ADP
brj-23874	148	12	statistically	statistically	ADV
brj-23874	148	13	significant	significant	ADJ
brj-23874	148	14	results	result	NOUN
brj-23874	148	15	(	(	PUNCT
brj-23874	148	16	p	p	X
brj-23874	148	17	<	<	X
brj-23874	148	18	0.05	0.05	NUM
brj-23874	148	19	at	at	ADP
brj-23874	148	20	30	30	NUM
brj-23874	148	21	minutes	minute	NOUN
brj-23874	148	22	and	and	CCONJ
brj-23874	148	23	p	p	X
brj-23874	148	24	<	<	X
brj-23874	148	25	0.001	0.001	NUM
brj-23874	148	26	at	at	ADP
brj-23874	148	27	120	120	NUM
brj-23874	148	28	minutes	minute	NOUN
brj-23874	148	29	)	)	PUNCT
brj-23874	148	30	in	in	ADP
brj-23874	148	31	comparison	comparison	NOUN
brj-23874	148	32	to	to	ADP
brj-23874	148	33	the	the	DET
brj-23874	148	34	control	control	NOUN
brj-23874	148	35	.	.	PUNCT
brj-23874	149	1	the	the	DET
brj-23874	149	2	pharmacological	pharmacological	ADJ
brj-23874	149	3	effects	effect	NOUN
brj-23874	149	4	of	of	ADP
brj-23874	149	5	the	the	DET
brj-23874	149	6	extracts	extract	NOUN
brj-23874	149	7	were	be	AUX
brj-23874	149	8	further	far	ADV
brj-23874	149	9	confirmed	confirm	VERB
brj-23874	149	10	by	by	ADP
brj-23874	149	11	the	the	DET
brj-23874	149	12	prolonged	prolonged	ADJ
brj-23874	149	13	latency	latency	NOUN
brj-23874	149	14	.	.	PUNCT
brj-23874	150	1	peer	peer	NOUN
brj-23874	150	2	-	-	PUNCT
brj-23874	150	3	reviewed	review	VERB
brj-23874	150	4	article	article	NOUN
brj-23874	150	5	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	150	6	zhu	zhu	PROPN
brj-23874	150	7	et	et	PROPN
brj-23874	150	8	al	al	PROPN
brj-23874	150	9	.	.	PROPN
brj-23874	151	1	(	(	PUNCT
brj-23874	151	2	2026	2026	NUM
brj-23874	151	3	)	)	PUNCT
brj-23874	151	4	.	.	PUNCT
brj-23874	152	1	“	"	PUNCT
brj-23874	152	2	pain	pain	NOUN
brj-23874	152	3	control	control	NOUN
brj-23874	152	4	with	with	ADP
brj-23874	152	5	seed	seed	NOUN
brj-23874	152	6	extract	extract	NOUN
brj-23874	152	7	,	,	PUNCT
brj-23874	152	8	”	"	PUNCT
brj-23874	152	9	bioresources	bioresource	NOUN
brj-23874	152	10	21(1	21(1	NUM
brj-23874	152	11	)	)	PUNCT
brj-23874	152	12	,	,	PUNCT
brj-23874	152	13	116	116	NUM
brj-23874	152	14	-	-	SYM
brj-23874	152	15	127	127	NUM
brj-23874	152	16	.	.	PUNCT
brj-23874	153	1	123	123	NUM
brj-23874	153	2	table	table	NOUN
brj-23874	153	3	2	2	NUM
brj-23874	153	4	.	.	PUNCT
brj-23874	153	5	effect	effect	NOUN
brj-23874	153	6	of	of	ADP
brj-23874	153	7	aqueous	aqueous	ADJ
brj-23874	153	8	seed	seed	NOUN
brj-23874	153	9	extract	extract	NOUN
brj-23874	153	10	of	of	ADP
brj-23874	153	11	c.	c.	PROPN
brj-23874	153	12	colocynthis	colocynthis	PROPN
brj-23874	153	13	on	on	ADP
brj-23874	153	14	hot	hot	ADJ
brj-23874	153	15	plate	plate	NOUN
brj-23874	153	16	test	test	NOUN
brj-23874	153	17	in	in	ADP
brj-23874	153	18	mice	mouse	NOUN
brj-23874	153	19	group	group	NOUN
brj-23874	153	20	0	0	NUM
brj-23874	153	21	30	30	NUM
brj-23874	153	22	min	min	NOUN
brj-23874	153	23	%	%	NOUN
brj-23874	153	24	60	60	NUM
brj-23874	153	25	min	min	NOUN
brj-23874	153	26	%	%	NOUN
brj-23874	153	27	90	90	NUM
brj-23874	153	28	min	min	NOUN
brj-23874	153	29	%	%	NOUN
brj-23874	153	30	120	120	NUM
brj-23874	153	31	min	min	NOUN
brj-23874	153	32	%	%	INTJ
brj-23874	153	33	dw	dw	PROPN
brj-23874	154	1	4.6	4.6	NUM
brj-23874	154	2	±	±	NUM
brj-23874	154	3	0.45	0.45	NUM
brj-23874	154	4	4.8	4.8	NUM
brj-23874	154	5	±	±	NUM
brj-23874	154	6	0.70	0.70	NUM
brj-23874	154	7	4.5	4.5	NUM
brj-23874	154	8	±	±	NUM
brj-23874	154	9	0.3	0.3	NUM
brj-23874	154	10	4.8	4.8	NUM
brj-23874	154	11	±	±	NUM
brj-23874	154	12	0.6	0.6	NUM
brj-23874	154	13	5.2	5.2	NUM
brj-23874	154	14	±	±	NUM
brj-23874	154	15	0.2	0.2	NUM
brj-23874	154	16	mo	mo	PROPN
brj-23874	154	17	3.8	3.8	NUM
brj-23874	154	18	±	±	NUM
brj-23874	154	19	0.50	0.50	NUM
brj-23874	154	20	7.0	7.0	NUM
brj-23874	154	21	±	±	NUM
brj-23874	154	22	0.35	0.35	NUM
brj-23874	154	23	29	29	NUM
brj-23874	154	24	%	%	NOUN
brj-23874	154	25	7.6	7.6	NUM
brj-23874	154	26	±	±	NUM
brj-23874	154	27	0.5	0.5	NUM
brj-23874	154	28	41	41	NUM
brj-23874	154	29	%	%	NOUN
brj-23874	154	30	8.6	8.6	NUM
brj-23874	154	31	±	±	NOUN
brj-23874	154	32	0.8	0.8	NUM
brj-23874	154	33	45	45	NUM
brj-23874	154	34	%	%	NOUN
brj-23874	154	35	14	14	NUM
brj-23874	154	36	±	±	NUM
brj-23874	154	37	0.8	0.8	NUM
brj-23874	154	38	80	80	NUM
brj-23874	154	39	%	%	NOUN
brj-23874	154	40	cc100	cc100	PROPN
brj-23874	154	41	3.4	3.4	NUM
brj-23874	154	42	±	±	NOUN
brj-23874	154	43	0.49	0.49	NUM
brj-23874	154	44	3.8	3.8	NUM
brj-23874	154	45	±	±	NUM
brj-23874	154	46	0.5	0.5	NUM
brj-23874	154	47	1.7	1.7	NUM
brj-23874	154	48	%	%	NOUN
brj-23874	154	49	4.2	4.2	NUM
brj-23874	154	50	±	±	NOUN
brj-23874	154	51	0.51	0.51	NUM
brj-23874	154	52	8.4	8.4	NUM
brj-23874	154	53	%	%	NOUN
brj-23874	154	54	5.0	5.0	NUM
brj-23874	154	55	±	±	NOUN
brj-23874	154	56	0.56	0.56	NUM
brj-23874	154	57	18	18	NUM
brj-23874	154	58	%	%	NOUN
brj-23874	154	59	6.8	6.8	NUM
brj-23874	154	60	±	±	NUM
brj-23874	154	61	1.1	1.1	NUM
brj-23874	154	62	30	30	NUM
brj-23874	154	63	%	%	NOUN
brj-23874	154	64	cc150	cc150	NOUN
brj-23874	154	65	4.2	4.2	NUM
brj-23874	154	66	±	±	NUM
brj-23874	154	67	0.52	0.52	NUM
brj-23874	154	68	6.2	6.2	NUM
brj-23874	154	69	±	±	NUM
brj-23874	154	70	0.34	0.34	NUM
brj-23874	154	71	18	18	NUM
brj-23874	154	72	%	%	NOUN
brj-23874	154	73	8.0	8.0	NUM
brj-23874	154	74	±0.56	±0.56	NOUN
brj-23874	154	75	36	36	NUM
brj-23874	154	76	%	%	NOUN
brj-23874	154	77	8.0	8.0	NUM
brj-23874	154	78	±	±	NUM
brj-23874	154	79	1.5	1.5	NUM
brj-23874	154	80	36	36	NUM
brj-23874	154	81	%	%	NOUN
brj-23874	154	82	14	14	NUM
brj-23874	154	83	±	±	NOUN
brj-23874	154	84	0.6	0.6	NUM
brj-23874	154	85	74	74	NUM
brj-23874	154	86	%	%	NOUN
brj-23874	154	87	cc200	cc200	PROPN
brj-23874	154	88	5.2	5.2	NUM
brj-23874	154	89	±	±	NUM
brj-23874	154	90	0.52	0.52	NUM
brj-23874	154	91	7.0	7.0	NUM
brj-23874	154	92	±	±	NUM
brj-23874	154	93	0.50	0.50	NUM
brj-23874	154	94	18	18	NUM
brj-23874	154	95	%	%	NOUN
brj-23874	154	96	8.0	8.0	NUM
brj-23874	154	97	±	±	NOUN
brj-23874	154	98	0.56	0.56	NUM
brj-23874	154	99	30	30	NUM
brj-23874	154	100	%	%	NOUN
brj-23874	154	101	10	10	NUM
brj-23874	154	102	±	±	NUM
brj-23874	154	103	1.15	1.15	NUM
brj-23874	154	104	50	50	NUM
brj-23874	154	105	%	%	NOUN
brj-23874	154	106	12	12	NUM
brj-23874	154	107	±	±	NUM
brj-23874	154	108	0.5	0.5	NUM
brj-23874	154	109	85	85	NUM
brj-23874	154	110	%	%	NOUN
brj-23874	154	111	assessment	assessment	NOUN
brj-23874	154	112	of	of	ADP
brj-23874	154	113	anti	anti	ADJ
brj-23874	154	114	-	-	ADJ
brj-23874	154	115	inflammatory	inflammatory	ADJ
brj-23874	154	116	activity	activity	NOUN
brj-23874	154	117	table	table	NOUN
brj-23874	154	118	3	3	NUM
brj-23874	154	119	shows	show	VERB
brj-23874	154	120	the	the	DET
brj-23874	154	121	results	result	NOUN
brj-23874	154	122	of	of	ADP
brj-23874	154	123	the	the	DET
brj-23874	154	124	carrageenan	carrageenan	NOUN
brj-23874	154	125	-	-	PUNCT
brj-23874	154	126	induced	induce	VERB
brj-23874	154	127	paw	paw	NOUN
brj-23874	154	128	swelling	swelling	NOUN
brj-23874	154	129	test	test	NOUN
brj-23874	154	130	with	with	ADP
brj-23874	154	131	the	the	DET
brj-23874	154	132	extract	extract	NOUN
brj-23874	154	133	and	and	CCONJ
brj-23874	154	134	indomethacin	indomethacin	NOUN
brj-23874	154	135	.	.	PUNCT
brj-23874	155	1	the	the	DET
brj-23874	155	2	carrageenan	carrageenan	NOUN
brj-23874	155	3	-	-	PUNCT
brj-23874	155	4	injected	inject	VERB
brj-23874	155	5	paws	paw	NOUN
brj-23874	155	6	reached	reach	VERB
brj-23874	155	7	their	their	PRON
brj-23874	155	8	maximum	maximum	ADJ
brj-23874	155	9	swelling	swell	VERB
brj-23874	155	10	3	3	NUM
brj-23874	155	11	h	h	NOUN
brj-23874	155	12	after	after	ADP
brj-23874	155	13	the	the	DET
brj-23874	155	14	injection	injection	NOUN
brj-23874	155	15	,	,	PUNCT
brj-23874	155	16	while	while	SCONJ
brj-23874	155	17	the	the	DET
brj-23874	155	18	control	control	PROPN
brj-23874	155	19	group	group	NOUN
brj-23874	155	20	’s	’s	PART
brj-23874	155	21	average	average	ADJ
brj-23874	155	22	volumetric	volumetric	NOUN
brj-23874	155	23	increase	increase	NOUN
brj-23874	155	24	was	be	AUX
brj-23874	155	25	about	about	ADV
brj-23874	155	26	100	100	NUM
brj-23874	155	27	%	%	NOUN
brj-23874	155	28	.	.	PUNCT
brj-23874	156	1	according	accord	VERB
brj-23874	156	2	to	to	ADP
brj-23874	156	3	statistical	statistical	ADJ
brj-23874	156	4	analyses	analysis	NOUN
brj-23874	156	5	,	,	PUNCT
brj-23874	156	6	different	different	ADJ
brj-23874	156	7	concentrations	concentration	NOUN
brj-23874	156	8	of	of	ADP
brj-23874	156	9	extract	extract	NOUN
brj-23874	156	10	(	(	PUNCT
brj-23874	156	11	50	50	NUM
brj-23874	156	12	,	,	PUNCT
brj-23874	156	13	100	100	NUM
brj-23874	156	14	,	,	PUNCT
brj-23874	156	15	and	and	CCONJ
brj-23874	156	16	150	150	NUM
brj-23874	156	17	mg	mg	NUM
brj-23874	156	18	/	/	SYM
brj-23874	156	19	kg	kg	NOUN
brj-23874	156	20	)	)	PUNCT
brj-23874	156	21	considerably	considerably	ADV
brj-23874	156	22	reduced	reduce	VERB
brj-23874	156	23	edema	edema	NOUN
brj-23874	156	24	compared	compare	VERB
brj-23874	156	25	to	to	ADP
brj-23874	156	26	the	the	DET
brj-23874	156	27	control	control	NOUN
brj-23874	156	28	group	group	NOUN
brj-23874	156	29	.	.	PUNCT
brj-23874	157	1	the	the	DET
brj-23874	157	2	edema	edema	NOUN
brj-23874	157	3	was	be	AUX
brj-23874	157	4	reduced	reduce	VERB
brj-23874	157	5	to	to	ADP
brj-23874	157	6	30.8	30.8	NUM
brj-23874	157	7	%	%	NOUN
brj-23874	157	8	3	3	NUM
brj-23874	157	9	h	h	NOUN
brj-23874	157	10	after	after	ADP
brj-23874	157	11	the	the	DET
brj-23874	157	12	carrageenan	carrageenan	NOUN
brj-23874	157	13	injection	injection	NOUN
brj-23874	157	14	in	in	ADP
brj-23874	157	15	different	different	ADJ
brj-23874	157	16	doses	dose	NOUN
brj-23874	157	17	of	of	ADP
brj-23874	157	18	c.	c.	PROPN
brj-23874	157	19	colocynthis	colocynthis	PROPN
brj-23874	157	20	extract	extract	NOUN
brj-23874	157	21	.	.	PUNCT
brj-23874	158	1	the	the	DET
brj-23874	158	2	results	result	NOUN
brj-23874	158	3	showed	show	VERB
brj-23874	158	4	that	that	SCONJ
brj-23874	158	5	the	the	DET
brj-23874	158	6	extract	extract	NOUN
brj-23874	158	7	at	at	ADP
brj-23874	158	8	150	150	NUM
brj-23874	158	9	mg	mg	NOUN
brj-23874	158	10	/	/	SYM
brj-23874	158	11	kg	kg	PROPN
brj-23874	158	12	was	be	AUX
brj-23874	158	13	more	more	ADV
brj-23874	158	14	effective	effective	ADJ
brj-23874	158	15	than	than	ADP
brj-23874	158	16	indomethacin	indomethacin	VERB
brj-23874	158	17	at	at	ADP
brj-23874	158	18	15	15	NUM
brj-23874	158	19	mg	mg	NOUN
brj-23874	158	20	/	/	SYM
brj-23874	158	21	kg	kg	NOUN
brj-23874	158	22	in	in	ADP
brj-23874	158	23	reducing	reduce	VERB
brj-23874	158	24	edema	edema	NOUN
brj-23874	158	25	.	.	PUNCT
brj-23874	159	1	there	there	PRON
brj-23874	159	2	was	be	VERB
brj-23874	159	3	no	no	DET
brj-23874	159	4	significant	significant	ADJ
brj-23874	159	5	difference	difference	NOUN
brj-23874	159	6	in	in	ADP
brj-23874	159	7	the	the	DET
brj-23874	159	8	effectiveness	effectiveness	NOUN
brj-23874	159	9	of	of	ADP
brj-23874	159	10	edema	edema	NOUN
brj-23874	159	11	reduction	reduction	NOUN
brj-23874	159	12	between	between	ADP
brj-23874	159	13	the	the	DET
brj-23874	159	14	150	150	NUM
brj-23874	159	15	and	and	CCONJ
brj-23874	159	16	100	100	NUM
brj-23874	159	17	mg	mg	NUM
brj-23874	159	18	/	/	SYM
brj-23874	159	19	kg	kg	PROPN
brj-23874	159	20	extract	extract	VERB
brj-23874	159	21	doses	dose	NOUN
brj-23874	159	22	(	(	PUNCT
brj-23874	159	23	p	p	X
brj-23874	159	24	>	>	X
brj-23874	159	25	0.05	0.05	NUM
brj-23874	159	26	)	)	PUNCT
brj-23874	159	27	.	.	PUNCT
brj-23874	160	1	the	the	DET
brj-23874	160	2	research	research	NOUN
brj-23874	160	3	discovered	discover	VERB
brj-23874	160	4	that	that	SCONJ
brj-23874	160	5	indomethacin	indomethacin	VERB
brj-23874	160	6	at	at	ADP
brj-23874	160	7	5	5	NUM
brj-23874	160	8	mg	mg	NOUN
brj-23874	160	9	/	/	SYM
brj-23874	160	10	kg	kg	NOUN
brj-23874	160	11	and	and	CCONJ
brj-23874	160	12	the	the	DET
brj-23874	160	13	extract	extract	NOUN
brj-23874	160	14	at	at	ADP
brj-23874	160	15	50	50	NUM
brj-23874	160	16	mg	mg	NOUN
brj-23874	160	17	/	/	SYM
brj-23874	160	18	kg	kg	NOUN
brj-23874	160	19	both	both	PRON
brj-23874	160	20	showed	show	VERB
brj-23874	160	21	similar	similar	ADJ
brj-23874	160	22	effectiveness	effectiveness	NOUN
brj-23874	160	23	in	in	ADP
brj-23874	160	24	reducing	reduce	VERB
brj-23874	160	25	rat	rat	NOUN
brj-23874	160	26	paw	paw	NOUN
brj-23874	160	27	swelling	swelling	NOUN
brj-23874	160	28	brought	bring	VERB
brj-23874	160	29	on	on	ADP
brj-23874	160	30	by	by	ADP
brj-23874	160	31	carrageenan	carrageenan	NOUN
brj-23874	160	32	.	.	PUNCT
brj-23874	161	1	in	in	ADP
brj-23874	161	2	contrast	contrast	NOUN
brj-23874	161	3	to	to	ADP
brj-23874	161	4	the	the	DET
brj-23874	161	5	reference	reference	NOUN
brj-23874	161	6	medication	medication	NOUN
brj-23874	161	7	,	,	PUNCT
brj-23874	161	8	the	the	DET
brj-23874	161	9	extract	extract	NOUN
brj-23874	161	10	exhibited	exhibit	VERB
brj-23874	161	11	substantial	substantial	ADJ
brj-23874	161	12	anti	anti	ADJ
brj-23874	161	13	-	-	ADJ
brj-23874	161	14	inflammatory	inflammatory	ADJ
brj-23874	161	15	properties	property	NOUN
brj-23874	161	16	.	.	PUNCT
brj-23874	162	1	as	as	SCONJ
brj-23874	162	2	evidenced	evidence	VERB
brj-23874	162	3	by	by	ADP
brj-23874	162	4	decreased	decrease	VERB
brj-23874	162	5	paw	paw	PROPN
brj-23874	162	6	edema	edema	PROPN
brj-23874	162	7	and	and	CCONJ
brj-23874	162	8	higher	high	ADJ
brj-23874	162	9	percent	percent	NOUN
brj-23874	162	10	edema	edema	NOUN
brj-23874	162	11	protection	protection	NOUN
brj-23874	162	12	in	in	ADP
brj-23874	162	13	carrageenan	carrageenan	NOUN
brj-23874	162	14	-	-	PUNCT
brj-23874	162	15	induced	induce	VERB
brj-23874	162	16	paw	paw	NOUN
brj-23874	162	17	edema	edema	PROPN
brj-23874	162	18	model	model	NOUN
brj-23874	162	19	,	,	PUNCT
brj-23874	162	20	cc	cc	NOUN
brj-23874	162	21	100	100	NUM
brj-23874	162	22	and	and	CCONJ
brj-23874	162	23	cc	cc	PROPN
brj-23874	162	24	150	150	NUM
brj-23874	162	25	demonstrated	demonstrate	VERB
brj-23874	162	26	strong	strong	ADJ
brj-23874	162	27	antiinflammatory	antiinflammatory	NOUN
brj-23874	162	28	properties	property	NOUN
brj-23874	162	29	.	.	PUNCT
brj-23874	163	1	according	accord	VERB
brj-23874	163	2	to	to	ADP
brj-23874	163	3	studies	study	NOUN
brj-23874	163	4	conducted	conduct	VERB
brj-23874	163	5	on	on	ADP
brj-23874	163	6	the	the	DET
brj-23874	163	7	biological	biological	ADJ
brj-23874	163	8	activities	activity	NOUN
brj-23874	163	9	of	of	ADP
brj-23874	163	10	the	the	DET
brj-23874	163	11	various	various	ADJ
brj-23874	163	12	phytochemicals	phytochemical	NOUN
brj-23874	163	13	,	,	PUNCT
brj-23874	163	14	the	the	DET
brj-23874	163	15	flavolignans	flavolignan	NOUN
brj-23874	163	16	(	(	PUNCT
brj-23874	163	17	shah	shah	PROPN
brj-23874	163	18	et	et	PROPN
brj-23874	163	19	al	al	PROPN
brj-23874	163	20	.	.	PROPN
brj-23874	163	21	2021	2021	NUM
brj-23874	163	22	)	)	PUNCT
brj-23874	163	23	and	and	CCONJ
brj-23874	163	24	flavones	flavone	NOUN
brj-23874	163	25	(	(	PUNCT
brj-23874	163	26	aboulaghras	aboulaghras	X
brj-23874	163	27	et	et	PROPN
brj-23874	163	28	al	al	PROPN
brj-23874	163	29	.	.	PROPN
brj-23874	163	30	2022	2022	NUM
brj-23874	163	31	)	)	PUNCT
brj-23874	163	32	glycosides	glycoside	NOUN
brj-23874	163	33	(	(	PUNCT
brj-23874	163	34	khan	khan	PROPN
brj-23874	163	35	et	et	PROPN
brj-23874	163	36	al	al	PROPN
brj-23874	163	37	.	.	PROPN
brj-23874	163	38	2020	2020	NUM
brj-23874	163	39	)	)	PUNCT
brj-23874	163	40	saponins	saponin	NOUN
brj-23874	163	41	(	(	PUNCT
brj-23874	163	42	passos	passos	X
brj-23874	163	43	et	et	PROPN
brj-23874	163	44	al	al	PROPN
brj-23874	163	45	.	.	PROPN
brj-23874	163	46	2021	2021	NUM
brj-23874	163	47	)	)	PUNCT
brj-23874	163	48	and	and	CCONJ
brj-23874	163	49	tannins	tannin	NOUN
brj-23874	163	50	(	(	PUNCT
brj-23874	163	51	soyocak	soyocak	NOUN
brj-23874	163	52	et	et	PROPN
brj-23874	163	53	al	al	PROPN
brj-23874	163	54	.	.	PROPN
brj-23874	163	55	2019	2019	NUM
brj-23874	163	56	)	)	PUNCT
brj-23874	163	57	have	have	AUX
brj-23874	163	58	been	be	AUX
brj-23874	163	59	shown	show	VERB
brj-23874	163	60	to	to	PART
brj-23874	163	61	induce	induce	VERB
brj-23874	163	62	analgesia	analgesia	NOUN
brj-23874	163	63	and	and	CCONJ
brj-23874	163	64	anti	anti	ADJ
brj-23874	163	65	-	-	ADJ
brj-23874	163	66	inflammatory	inflammatory	ADJ
brj-23874	163	67	effects	effect	NOUN
brj-23874	163	68	due	due	ADP
brj-23874	163	69	to	to	ADP
brj-23874	163	70	their	their	PRON
brj-23874	163	71	ability	ability	NOUN
brj-23874	163	72	to	to	PART
brj-23874	163	73	inhibit	inhibit	VERB
brj-23874	163	74	key	key	ADJ
brj-23874	163	75	enzymes	enzyme	NOUN
brj-23874	163	76	involved	involve	VERB
brj-23874	163	77	in	in	ADP
brj-23874	163	78	the	the	DET
brj-23874	163	79	inflammation	inflammation	NOUN
brj-23874	163	80	process	process	NOUN
brj-23874	163	81	such	such	ADJ
brj-23874	163	82	as	as	ADP
brj-23874	163	83	cox-1	cox-1	PUNCT
brj-23874	163	84	(	(	PUNCT
brj-23874	163	85	cyclooxygenase	cyclooxygenase	NOUN
brj-23874	163	86	1	1	NUM
brj-23874	163	87	)	)	PUNCT
brj-23874	163	88	,	,	PUNCT
brj-23874	163	89	cox-2	cox-2	PRON
brj-23874	163	90	(	(	PUNCT
brj-23874	163	91	cyclooxygenase	cyclooxygenase	NOUN
brj-23874	163	92	2	2	NUM
brj-23874	163	93	)	)	PUNCT
brj-23874	163	94	,	,	PUNCT
brj-23874	163	95	spla2	spla2	X
brj-23874	164	1	(	(	PUNCT
brj-23874	164	2	secretory	secretory	ADJ
brj-23874	164	3	phospholipase	phospholipase	NOUN
brj-23874	164	4	a2	a2	PROPN
brj-23874	164	5	)	)	PUNCT
brj-23874	164	6	,	,	PUNCT
brj-23874	164	7	and	and	CCONJ
brj-23874	164	8	15	15	NUM
brj-23874	164	9	-	-	PUNCT
brj-23874	164	10	lox-2	lox-2	NOUN
brj-23874	164	11	(	(	PUNCT
brj-23874	164	12	15	15	NUM
brj-23874	164	13	-	-	PUNCT
brj-23874	164	14	lipoxygenase	lipoxygenase	NOUN
brj-23874	164	15	)	)	PUNCT
brj-23874	164	16	.	.	PUNCT
brj-23874	165	1	the	the	DET
brj-23874	165	2	extracts	extract	NOUN
brj-23874	165	3	and	and	CCONJ
brj-23874	165	4	standard	standard	ADJ
brj-23874	165	5	drug	drug	NOUN
brj-23874	165	6	exhibited	exhibit	VERB
brj-23874	165	7	their	their	PRON
brj-23874	165	8	pharmacological	pharmacological	ADJ
brj-23874	165	9	activity	activity	NOUN
brj-23874	165	10	after	after	ADP
brj-23874	165	11	3	3	NUM
brj-23874	165	12	hr	hr	NOUN
brj-23874	165	13	.	.	PUNCT
brj-23874	166	1	this	this	PRON
brj-23874	166	2	might	might	AUX
brj-23874	166	3	be	be	AUX
brj-23874	166	4	explained	explain	VERB
brj-23874	166	5	by	by	ADP
brj-23874	166	6	the	the	DET
brj-23874	166	7	lag	lag	NOUN
brj-23874	166	8	-	-	PUNCT
brj-23874	166	9	time	time	NOUN
brj-23874	166	10	required	require	VERB
brj-23874	166	11	for	for	ADP
brj-23874	166	12	extract	extract	NOUN
brj-23874	166	13	and	and	CCONJ
brj-23874	166	14	drug	drug	NOUN
brj-23874	166	15	to	to	PART
brj-23874	166	16	reach	reach	VERB
brj-23874	166	17	the	the	DET
brj-23874	166	18	site	site	NOUN
brj-23874	166	19	of	of	ADP
brj-23874	166	20	action	action	NOUN
brj-23874	166	21	.	.	PUNCT
brj-23874	167	1	peer	peer	NOUN
brj-23874	167	2	-	-	PUNCT
brj-23874	167	3	reviewed	review	VERB
brj-23874	167	4	article	article	NOUN
brj-23874	167	5	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	167	6	zhu	zhu	PROPN
brj-23874	167	7	et	et	PROPN
brj-23874	167	8	al	al	PROPN
brj-23874	167	9	.	.	PROPN
brj-23874	168	1	(	(	PUNCT
brj-23874	168	2	2026	2026	NUM
brj-23874	168	3	)	)	PUNCT
brj-23874	168	4	.	.	PUNCT
brj-23874	169	1	“	"	PUNCT
brj-23874	169	2	pain	pain	NOUN
brj-23874	169	3	control	control	NOUN
brj-23874	169	4	with	with	ADP
brj-23874	169	5	seed	seed	NOUN
brj-23874	169	6	extract	extract	NOUN
brj-23874	169	7	,	,	PUNCT
brj-23874	169	8	”	"	PUNCT
brj-23874	169	9	bioresources	bioresource	NOUN
brj-23874	169	10	21(1	21(1	NUM
brj-23874	169	11	)	)	PUNCT
brj-23874	169	12	,	,	PUNCT
brj-23874	169	13	116	116	NUM
brj-23874	169	14	-	-	SYM
brj-23874	169	15	127	127	NUM
brj-23874	169	16	.	.	PUNCT
brj-23874	170	1	124	124	NUM
brj-23874	170	2	table	table	NOUN
brj-23874	170	3	3	3	NUM
brj-23874	170	4	.	.	PUNCT
brj-23874	170	5	anti	anti	ADJ
brj-23874	170	6	-	-	ADJ
brj-23874	170	7	inflammatory	inflammatory	ADJ
brj-23874	170	8	effect	effect	NOUN
brj-23874	170	9	of	of	ADP
brj-23874	170	10	indomethacin	indomethacin	NOUN
brj-23874	170	11	and	and	CCONJ
brj-23874	170	12	c.	c.	PROPN
brj-23874	170	13	colocynthis	colocynthis	PROPN
brj-23874	170	14	extract	extract	NOUN
brj-23874	170	15	on	on	ADP
brj-23874	170	16	carrageenan	carrageenan	NOUN
brj-23874	170	17	induced	induce	VERB
brj-23874	170	18	paw	paw	NOUN
brj-23874	170	19	edema	edema	PROPN
brj-23874	170	20	treatment	treatment	NOUN
brj-23874	170	21	dose	dose	NOUN
brj-23874	170	22	(	(	PUNCT
brj-23874	170	23	mg	mg	PROPN
brj-23874	170	24	/	/	SYM
brj-23874	170	25	kg	kg	NOUN
brj-23874	170	26	)	)	PUNCT
brj-23874	170	27	degree	degree	NOUN
brj-23874	170	28	of	of	ADP
brj-23874	170	29	swelling	swell	VERB
brj-23874	170	30	s.e.m	s.e.m	NOUN
brj-23874	170	31	edema	edema	NOUN
brj-23874	170	32	inhibition	inhibition	NOUN
brj-23874	170	33	(	(	PUNCT
brj-23874	170	34	%	%	INTJ
brj-23874	170	35	)	)	PUNCT
brj-23874	170	36	control	control	NOUN
brj-23874	170	37	1.99	1.99	NUM
brj-23874	170	38	±	±	NUM
brj-23874	170	39	0.010	0.010	NUM
brj-23874	170	40	0	0	NUM
brj-23874	170	41	cc	cc	ADP
brj-23874	170	42	50	50	NUM
brj-23874	170	43	1.25	1.25	NUM
brj-23874	170	44	±	±	NUM
brj-23874	170	45	0.022	0.022	NUM
brj-23874	170	46	70.4	70.4	NUM
brj-23874	170	47	±	±	NUM
brj-23874	170	48	3.015	3.015	NUM
brj-23874	170	49	cc	cc	PROPN
brj-23874	170	50	100	100	NUM
brj-23874	170	51	1.05	1.05	NUM
brj-23874	170	52	±	±	NUM
brj-23874	170	53	0.021	0.021	NUM
brj-23874	170	54	90.5	90.5	NUM
brj-23874	170	55	±	±	NUM
brj-23874	170	56	2.06	2.06	NUM
brj-23874	170	57	cc	cc	PROPN
brj-23874	170	58	150	150	NUM
brj-23874	170	59	1.01	1.01	NUM
brj-23874	170	60	±	±	NUM
brj-23874	170	61	0.023	0.023	NUM
brj-23874	170	62	96.8	96.8	NUM
brj-23874	170	63	±	±	NUM
brj-23874	170	64	2.15	2.15	NUM
brj-23874	170	65	control	control	NOUN
brj-23874	170	66	1.99	1.99	NUM
brj-23874	170	67	±	±	NUM
brj-23874	170	68	0.010	0.010	NUM
brj-23874	170	69	0	0	NUM
brj-23874	170	70	indomethacin	indomethacin	VERB
brj-23874	170	71	5	5	NUM
brj-23874	170	72	1.30	1.30	NUM
brj-23874	170	73	±	±	NUM
brj-23874	170	74	0.025	0.025	NUM
brj-23874	170	75	69.7	69.7	NUM
brj-23874	170	76	±	±	NOUN
brj-23874	170	77	2.51	2.51	NUM
brj-23874	170	78	indomethacin	indomethacin	VERB
brj-23874	170	79	10	10	NUM
brj-23874	170	80	1.28	1.28	NUM
brj-23874	170	81	±	±	NUM
brj-23874	170	82	0.023	0.023	NUM
brj-23874	170	83	74.5	74.5	NUM
brj-23874	170	84	±	±	NUM
brj-23874	170	85	2.34	2.34	NUM
brj-23874	170	86	indomethacin	indomethacin	VERB
brj-23874	170	87	15	15	NUM
brj-23874	170	88	1.15	1.15	NUM
brj-23874	170	89	±	±	NUM
brj-23874	170	90	0.020	0.020	NUM
brj-23874	170	91	80.00	80.00	NUM
brj-23874	170	92	±	±	NUM
brj-23874	170	93	2.26	2.26	NUM
brj-23874	170	94	conclusions	conclusion	NOUN
brj-23874	170	95	1	1	NUM
brj-23874	170	96	.	.	PUNCT
brj-23874	171	1	the	the	DET
brj-23874	171	2	results	result	NOUN
brj-23874	171	3	suggested	suggest	VERB
brj-23874	171	4	that	that	SCONJ
brj-23874	171	5	the	the	DET
brj-23874	171	6	aqueous	aqueous	ADJ
brj-23874	171	7	seed	seed	NOUN
brj-23874	171	8	extract	extract	NOUN
brj-23874	171	9	of	of	ADP
brj-23874	171	10	citrullus	citrullus	PROPN
brj-23874	171	11	colocynthis	colocynthis	PROPN
brj-23874	171	12	possesses	possess	VERB
brj-23874	171	13	substantial	substantial	ADJ
brj-23874	171	14	anti	anti	ADJ
brj-23874	171	15	-	-	ADJ
brj-23874	171	16	inflammatory	inflammatory	ADJ
brj-23874	171	17	properties	property	NOUN
brj-23874	171	18	.	.	PUNCT
brj-23874	172	1	furthermore	furthermore	ADV
brj-23874	172	2	,	,	PUNCT
brj-23874	172	3	it	it	PRON
brj-23874	172	4	is	be	AUX
brj-23874	172	5	essential	essential	ADJ
brj-23874	172	6	for	for	ADP
brj-23874	172	7	the	the	DET
brj-23874	172	8	relief	relief	NOUN
brj-23874	172	9	of	of	ADP
brj-23874	172	10	central	central	ADJ
brj-23874	172	11	pain	pain	NOUN
brj-23874	172	12	and	and	CCONJ
brj-23874	172	13	exhibits	exhibit	VERB
brj-23874	172	14	strong	strong	ADJ
brj-23874	172	15	peripheral	peripheral	ADJ
brj-23874	172	16	antinociceptive	antinociceptive	ADJ
brj-23874	172	17	activity	activity	NOUN
brj-23874	172	18	.	.	PUNCT
brj-23874	173	1	2	2	X
brj-23874	173	2	.	.	X
brj-23874	173	3	the	the	DET
brj-23874	173	4	cytotoxic	cytotoxic	ADJ
brj-23874	173	5	,	,	PUNCT
brj-23874	173	6	antibacterial	antibacterial	ADJ
brj-23874	173	7	,	,	PUNCT
brj-23874	173	8	analgesic	analgesic	ADJ
brj-23874	173	9	,	,	PUNCT
brj-23874	173	10	and	and	CCONJ
brj-23874	173	11	anti	anti	ADJ
brj-23874	173	12	-	-	ADJ
brj-23874	173	13	inflammatory	inflammatory	ADJ
brj-23874	173	14	qualities	quality	NOUN
brj-23874	173	15	of	of	ADP
brj-23874	173	16	the	the	DET
brj-23874	173	17	extract	extract	NOUN
brj-23874	173	18	are	be	AUX
brj-23874	173	19	probably	probably	ADV
brj-23874	173	20	due	due	ADJ
brj-23874	173	21	to	to	ADP
brj-23874	173	22	the	the	DET
brj-23874	173	23	phytochemical	phytochemical	ADJ
brj-23874	173	24	components	component	NOUN
brj-23874	173	25	.	.	PUNCT
brj-23874	174	1	c.	c.	PROPN
brj-23874	174	2	colocynthis	colocynthis	PROPN
brj-23874	174	3	extract	extract	NOUN
brj-23874	174	4	also	also	ADV
brj-23874	174	5	was	be	AUX
brj-23874	174	6	evaluated	evaluate	VERB
brj-23874	174	7	for	for	ADP
brj-23874	174	8	its	its	PRON
brj-23874	174	9	cytotoxicity	cytotoxicity	NOUN
brj-23874	174	10	against	against	ADP
brj-23874	174	11	malignant	malignant	ADJ
brj-23874	174	12	cell	cell	NOUN
brj-23874	174	13	lines	line	NOUN
brj-23874	174	14	,	,	PUNCT
brj-23874	174	15	and	and	CCONJ
brj-23874	174	16	the	the	DET
brj-23874	174	17	results	result	NOUN
brj-23874	174	18	showed	show	VERB
brj-23874	174	19	that	that	SCONJ
brj-23874	174	20	it	it	PRON
brj-23874	174	21	was	be	AUX
brj-23874	174	22	rather	rather	ADV
brj-23874	174	23	effective	effective	ADJ
brj-23874	174	24	against	against	ADP
brj-23874	174	25	all	all	DET
brj-23874	174	26	tested	test	VERB
brj-23874	174	27	gram	gram	ADJ
brj-23874	174	28	-	-	PUNCT
brj-23874	174	29	positive	positive	ADJ
brj-23874	174	30	bacteria	bacteria	NOUN
brj-23874	174	31	.	.	PUNCT
brj-23874	175	1	3	3	X
brj-23874	175	2	.	.	X
brj-23874	175	3	using	use	VERB
brj-23874	175	4	the	the	DET
brj-23874	175	5	hot	hot	ADJ
brj-23874	175	6	plate	plate	NOUN
brj-23874	175	7	approach	approach	NOUN
brj-23874	175	8	for	for	ADP
brj-23874	175	9	analgesia	analgesia	PROPN
brj-23874	175	10	assessment	assessment	NOUN
brj-23874	175	11	,	,	PUNCT
brj-23874	175	12	the	the	DET
brj-23874	175	13	best	good	ADJ
brj-23874	175	14	pain	pain	NOUN
brj-23874	175	15	alleviation	alleviation	NOUN
brj-23874	175	16	was	be	AUX
brj-23874	175	17	seen	see	VERB
brj-23874	175	18	in	in	ADP
brj-23874	175	19	all	all	DET
brj-23874	175	20	experimental	experimental	ADJ
brj-23874	175	21	groups	group	NOUN
brj-23874	175	22	at	at	ADP
brj-23874	175	23	the	the	DET
brj-23874	175	24	120	120	NUM
brj-23874	175	25	-	-	PUNCT
brj-23874	175	26	min	min	NOUN
brj-23874	175	27	point	point	NOUN
brj-23874	175	28	.	.	PUNCT
brj-23874	176	1	in	in	ADP
brj-23874	176	2	the	the	DET
brj-23874	176	3	carrageenan	carrageenan	NOUN
brj-23874	176	4	-	-	PUNCT
brj-23874	176	5	induced	induce	VERB
brj-23874	176	6	paw	paw	NOUN
brj-23874	176	7	edema	edema	PROPN
brj-23874	176	8	model	model	NOUN
brj-23874	176	9	,	,	PUNCT
brj-23874	176	10	the	the	DET
brj-23874	176	11	variants	variant	NOUN
brj-23874	176	12	cc150	cc150	PROPN
brj-23874	176	13	and	and	CCONJ
brj-23874	176	14	cc200	cc200	PROPN
brj-23874	176	15	exhibited	exhibit	VERB
brj-23874	176	16	strong	strong	ADJ
brj-23874	176	17	antiinflammatory	antiinflammatory	NOUN
brj-23874	176	18	properties	property	NOUN
brj-23874	176	19	,	,	PUNCT
brj-23874	176	20	as	as	SCONJ
brj-23874	176	21	shown	show	VERB
brj-23874	176	22	by	by	ADP
brj-23874	176	23	decreased	decrease	VERB
brj-23874	176	24	paw	paw	NOUN
brj-23874	176	25	swelling	swelling	NOUN
brj-23874	176	26	and	and	CCONJ
brj-23874	176	27	a	a	DET
brj-23874	176	28	greater	great	ADJ
brj-23874	176	29	percentage	percentage	NOUN
brj-23874	176	30	of	of	ADP
brj-23874	176	31	edema	edema	NOUN
brj-23874	176	32	prevention	prevention	NOUN
brj-23874	176	33	.	.	PUNCT
brj-23874	177	1	therefore	therefore	ADV
brj-23874	177	2	,	,	PUNCT
brj-23874	177	3	this	this	DET
brj-23874	177	4	study	study	NOUN
brj-23874	177	5	validates	validate	VERB
brj-23874	177	6	the	the	DET
brj-23874	177	7	use	use	NOUN
brj-23874	177	8	of	of	ADP
brj-23874	177	9	c.	c.	PROPN
brj-23874	177	10	colocynthis	colocynthis	PROPN
brj-23874	177	11	aqueous	aqueous	ADJ
brj-23874	177	12	seed	seed	NOUN
brj-23874	177	13	extract	extract	NOUN
brj-23874	177	14	in	in	ADP
brj-23874	177	15	folk	folk	NOUN
brj-23874	177	16	medicine	medicine	NOUN
brj-23874	177	17	,	,	PUNCT
brj-23874	177	18	supporting	support	VERB
brj-23874	177	19	its	its	PRON
brj-23874	177	20	traditional	traditional	ADJ
brj-23874	177	21	use	use	NOUN
brj-23874	177	22	for	for	ADP
brj-23874	177	23	the	the	DET
brj-23874	177	24	management	management	NOUN
brj-23874	177	25	of	of	ADP
brj-23874	177	26	pain	pain	NOUN
brj-23874	177	27	and	and	CCONJ
brj-23874	177	28	inflammation	inflammation	NOUN
brj-23874	177	29	.	.	PUNCT
brj-23874	178	1	4	4	X
brj-23874	178	2	.	.	X
brj-23874	178	3	future	future	ADJ
brj-23874	178	4	research	research	NOUN
brj-23874	178	5	on	on	ADP
brj-23874	178	6	c.	c.	PROPN
brj-23874	178	7	colocynthis	colocynthis	PROPN
brj-23874	178	8	aqueous	aqueous	ADJ
brj-23874	178	9	seed	seed	NOUN
brj-23874	178	10	extract	extract	NOUN
brj-23874	178	11	ought	ought	AUX
brj-23874	178	12	to	to	PART
brj-23874	178	13	include	include	VERB
brj-23874	178	14	the	the	DET
brj-23874	178	15	exploration	exploration	NOUN
brj-23874	178	16	of	of	ADP
brj-23874	178	17	combination	combination	NOUN
brj-23874	178	18	therapies	therapy	NOUN
brj-23874	178	19	and	and	CCONJ
brj-23874	178	20	expanded	expand	VERB
brj-23874	178	21	clinical	clinical	ADJ
brj-23874	178	22	trials	trial	NOUN
brj-23874	178	23	to	to	PART
brj-23874	178	24	improve	improve	VERB
brj-23874	178	25	its	its	PRON
brj-23874	178	26	anti	anti	ADJ
brj-23874	178	27	-	-	ADJ
brj-23874	178	28	inflammatory	inflammatory	ADJ
brj-23874	178	29	and	and	CCONJ
brj-23874	178	30	analgesic	analgesic	ADJ
brj-23874	178	31	effects	effect	NOUN
brj-23874	178	32	.	.	PUNCT
brj-23874	179	1	it	it	PRON
brj-23874	179	2	is	be	AUX
brj-23874	179	3	important	important	ADJ
brj-23874	179	4	to	to	PART
brj-23874	179	5	conduct	conduct	VERB
brj-23874	179	6	comprehensive	comprehensive	ADJ
brj-23874	179	7	toxicological	toxicological	ADJ
brj-23874	179	8	studies	study	NOUN
brj-23874	179	9	to	to	PART
brj-23874	179	10	understand	understand	VERB
brj-23874	179	11	the	the	DET
brj-23874	179	12	safety	safety	NOUN
brj-23874	179	13	of	of	ADP
brj-23874	179	14	its	its	PRON
brj-23874	179	15	long	long	ADJ
brj-23874	179	16	-	-	PUNCT
brj-23874	179	17	term	term	NOUN
brj-23874	179	18	use	use	NOUN
brj-23874	179	19	.	.	PUNCT
brj-23874	180	1	5	5	X
brj-23874	180	2	.	.	X
brj-23874	180	3	furthermore	furthermore	ADV
brj-23874	180	4	,	,	PUNCT
brj-23874	180	5	initiatives	initiative	NOUN
brj-23874	180	6	should	should	AUX
brj-23874	180	7	prioritise	prioritise	VERB
brj-23874	180	8	the	the	DET
brj-23874	180	9	standardisation	standardisation	NOUN
brj-23874	180	10	and	and	CCONJ
brj-23874	180	11	advancement	advancement	NOUN
brj-23874	180	12	of	of	ADP
brj-23874	180	13	pharmaceutical	pharmaceutical	NOUN
brj-23874	180	14	formulations	formulation	NOUN
brj-23874	180	15	to	to	PART
brj-23874	180	16	guarantee	guarantee	VERB
brj-23874	180	17	consistent	consistent	ADJ
brj-23874	180	18	safety	safety	NOUN
brj-23874	180	19	and	and	CCONJ
brj-23874	180	20	efficacy	efficacy	NOUN
brj-23874	180	21	.	.	PUNCT
brj-23874	181	1	addressing	address	VERB
brj-23874	181	2	these	these	DET
brj-23874	181	3	areas	area	NOUN
brj-23874	181	4	could	could	AUX
brj-23874	181	5	reinforce	reinforce	VERB
brj-23874	181	6	existing	exist	VERB
brj-23874	181	7	discoveries	discovery	NOUN
brj-23874	181	8	and	and	CCONJ
brj-23874	181	9	establish	establish	VERB
brj-23874	181	10	the	the	DET
brj-23874	181	11	foundation	foundation	NOUN
brj-23874	181	12	for	for	ADP
brj-23874	181	13	novel	novel	ADJ
brj-23874	181	14	therapeutic	therapeutic	ADJ
brj-23874	181	15	applications	application	NOUN
brj-23874	181	16	.	.	PUNCT
brj-23874	182	1	peer	peer	NOUN
brj-23874	182	2	-	-	PUNCT
brj-23874	182	3	reviewed	review	VERB
brj-23874	182	4	article	article	NOUN
brj-23874	182	5	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	182	6	zhu	zhu	PROPN
brj-23874	182	7	et	et	PROPN
brj-23874	182	8	al	al	PROPN
brj-23874	182	9	.	.	PROPN
brj-23874	183	1	(	(	PUNCT
brj-23874	183	2	2026	2026	NUM
brj-23874	183	3	)	)	PUNCT
brj-23874	183	4	.	.	PUNCT
brj-23874	184	1	“	"	PUNCT
brj-23874	184	2	pain	pain	NOUN
brj-23874	184	3	control	control	NOUN
brj-23874	184	4	with	with	ADP
brj-23874	184	5	seed	seed	NOUN
brj-23874	184	6	extract	extract	NOUN
brj-23874	184	7	,	,	PUNCT
brj-23874	184	8	”	"	PUNCT
brj-23874	184	9	bioresources	bioresource	NOUN
brj-23874	184	10	21(1	21(1	NUM
brj-23874	184	11	)	)	PUNCT
brj-23874	184	12	,	,	PUNCT
brj-23874	184	13	116	116	NUM
brj-23874	184	14	-	-	SYM
brj-23874	184	15	127	127	NUM
brj-23874	184	16	.	.	PUNCT
brj-23874	185	1	125	125	NUM
brj-23874	185	2	acknowledgments	acknowledgment	NOUN
brj-23874	185	3	authors	author	NOUN
brj-23874	185	4	are	be	AUX
brj-23874	185	5	thankful	thankful	ADJ
brj-23874	185	6	to	to	ADP
brj-23874	185	7	xi’an	xi’an	PROPN
brj-23874	185	8	jiaotong	jiaotong	PROPN
brj-23874	185	9	-	-	PUNCT
brj-23874	185	10	liverpool	liverpool	PROPN
brj-23874	185	11	university	university	NOUN
brj-23874	185	12	for	for	ADP
brj-23874	185	13	providing	provide	VERB
brj-23874	185	14	platform	platform	NOUN
brj-23874	185	15	to	to	PART
brj-23874	185	16	do	do	VERB
brj-23874	185	17	this	this	DET
brj-23874	185	18	research	research	NOUN
brj-23874	185	19	.	.	PUNCT
brj-23874	186	1	data	datum	NOUN
brj-23874	186	2	availability	availability	NOUN
brj-23874	186	3	the	the	DET
brj-23874	186	4	data	datum	NOUN
brj-23874	186	5	pertaining	pertain	VERB
brj-23874	186	6	to	to	ADP
brj-23874	186	7	the	the	DET
brj-23874	186	8	conclusions	conclusion	NOUN
brj-23874	186	9	of	of	ADP
brj-23874	186	10	this	this	DET
brj-23874	186	11	study	study	NOUN
brj-23874	186	12	can	can	AUX
brj-23874	186	13	be	be	AUX
brj-23874	186	14	obtained	obtain	VERB
brj-23874	186	15	from	from	ADP
brj-23874	186	16	the	the	DET
brj-23874	186	17	respective	respective	ADJ
brj-23874	186	18	authors	author	NOUN
brj-23874	186	19	upon	upon	SCONJ
brj-23874	186	20	a	a	DET
brj-23874	186	21	reasonable	reasonable	ADJ
brj-23874	186	22	request	request	NOUN
brj-23874	186	23	.	.	PUNCT
brj-23874	187	1	conflict	conflict	NOUN
brj-23874	187	2	of	of	ADP
brj-23874	187	3	interest	interest	NOUN
brj-23874	187	4	all	all	DET
brj-23874	187	5	the	the	DET
brj-23874	187	6	authors	author	NOUN
brj-23874	187	7	have	have	AUX
brj-23874	187	8	declared	declare	VERB
brj-23874	187	9	that	that	SCONJ
brj-23874	187	10	no	no	DET
brj-23874	187	11	conflict	conflict	NOUN
brj-23874	187	12	of	of	ADP
brj-23874	187	13	interest	interest	NOUN
brj-23874	187	14	related	relate	VERB
brj-23874	187	15	to	to	ADP
brj-23874	187	16	this	this	DET
brj-23874	187	17	work	work	NOUN
brj-23874	187	18	.	.	PUNCT
brj-23874	188	1	references	reference	NOUN
brj-23874	188	2	cited	cite	VERB
brj-23874	188	3	abbas	abbas	PROPN
brj-23874	188	4	,	,	PUNCT
brj-23874	188	5	d.	d.	PROPN
brj-23874	188	6	a.	a.	PROPN
brj-23874	188	7	(	(	PUNCT
brj-23874	188	8	2013	2013	NUM
brj-23874	188	9	)	)	PUNCT
brj-23874	188	10	.	.	PUNCT
brj-23874	189	1	“	"	PUNCT
brj-23874	189	2	analgesic	analgesic	ADJ
brj-23874	189	3	,	,	PUNCT
brj-23874	189	4	anti	anti	ADJ
brj-23874	189	5	-	-	ADJ
brj-23874	189	6	inflammatory	inflammatory	ADJ
brj-23874	189	7	and	and	CCONJ
brj-23874	189	8	antidiarrheal	antidiarrheal	ADJ
brj-23874	189	9	effects	effect	NOUN
brj-23874	189	10	of	of	ADP
brj-23874	189	11	datura	datura	NOUN
brj-23874	189	12	stramonium	stramonium	NOUN
brj-23874	189	13	hydroalcoholic	hydroalcoholic	PROPN
brj-23874	189	14	leaves	leave	NOUN
brj-23874	189	15	extract	extract	VERB
brj-23874	189	16	in	in	ADP
brj-23874	189	17	mice	mouse	NOUN
brj-23874	189	18	,	,	PUNCT
brj-23874	189	19	”	"	PUNCT
brj-23874	189	20	ijrras	ijrras	NOUN
brj-23874	189	21	14	14	NUM
brj-23874	189	22	,	,	PUNCT
brj-23874	189	23	193	193	NUM
brj-23874	189	24	-	-	SYM
brj-23874	189	25	199	199	NUM
brj-23874	189	26	.	.	PUNCT
brj-23874	190	1	aboulaghras	aboulaghras	PROPN
brj-23874	190	2	,	,	PUNCT
brj-23874	190	3	s.	s.	PROPN
brj-23874	190	4	,	,	PUNCT
brj-23874	190	5	sahib	sahib	NOUN
brj-23874	190	6	,	,	PUNCT
brj-23874	190	7	n.	n.	NOUN
brj-23874	190	8	,	,	PUNCT
brj-23874	190	9	bakrim	bakrim	ADV
brj-23874	190	10	,	,	PUNCT
brj-23874	190	11	s.	s.	PROPN
brj-23874	190	12	,	,	PUNCT
brj-23874	190	13	benali	benali	VERB
brj-23874	190	14	,	,	PUNCT
brj-23874	190	15	t.	t.	PROPN
brj-23874	190	16	,	,	PUNCT
brj-23874	190	17	charfi	charfi	PROPN
brj-23874	190	18	,	,	PUNCT
brj-23874	190	19	s.	s.	PROPN
brj-23874	190	20	,	,	PUNCT
brj-23874	190	21	guaouguaou	guaouguaou	NOUN
brj-23874	190	22	,	,	PUNCT
brj-23874	190	23	f.-e	f.-e	NOUN
brj-23874	190	24	.	.	PUNCT
brj-23874	190	25	,	,	PUNCT
brj-23874	190	26	omari	omari	PROPN
brj-23874	190	27	,	,	PUNCT
brj-23874	190	28	n.	n.	PROPN
brj-23874	190	29	e.	e.	PROPN
brj-23874	190	30	,	,	PUNCT
brj-23874	190	31	gallo	gallo	PROPN
brj-23874	190	32	,	,	PUNCT
brj-23874	190	33	m.	m.	NOUN
brj-23874	190	34	,	,	PUNCT
brj-23874	190	35	montesano	montesano	PROPN
brj-23874	190	36	,	,	PUNCT
brj-23874	190	37	d.	d.	PROPN
brj-23874	190	38	,	,	PUNCT
brj-23874	190	39	zengin	zengin	NOUN
brj-23874	190	40	,	,	PUNCT
brj-23874	190	41	g.	g.	PROPN
brj-23874	190	42	,	,	PUNCT
brj-23874	190	43	taghzouti	taghzouti	PROPN
brj-23874	190	44	,	,	PUNCT
brj-23874	190	45	k.	k.	PROPN
brj-23874	190	46	,	,	PUNCT
brj-23874	190	47	and	and	CCONJ
brj-23874	190	48	bouyahya	bouyahya	PROPN
brj-23874	190	49	,	,	PUNCT
brj-23874	190	50	a.	a.	NOUN
brj-23874	190	51	(	(	PUNCT
brj-23874	190	52	2022	2022	NUM
brj-23874	190	53	)	)	PUNCT
brj-23874	190	54	.	.	PUNCT
brj-23874	191	1	“	"	PUNCT
brj-23874	191	2	health	health	NOUN
brj-23874	191	3	benefits	benefit	NOUN
brj-23874	191	4	and	and	CCONJ
brj-23874	191	5	pharmacological	pharmacological	ADJ
brj-23874	191	6	aspects	aspect	NOUN
brj-23874	191	7	of	of	ADP
brj-23874	191	8	chrysoeriol	chrysoeriol	NOUN
brj-23874	191	9	,	,	PUNCT
brj-23874	191	10	”	"	PUNCT
brj-23874	191	11	pharmaceuticals	pharmaceutical	NOUN
brj-23874	191	12	15(8	15(8	NUM
brj-23874	191	13	)	)	PUNCT
brj-23874	191	14	,	,	PUNCT
brj-23874	191	15	article	article	NOUN
brj-23874	191	16	973	973	NUM
brj-23874	191	17	.	.	PUNCT
brj-23874	192	1	doi	doi	NOUN
brj-23874	192	2	:	:	PUNCT
brj-23874	192	3	10.3390	10.3390	NUM
brj-23874	192	4	/	/	SYM
brj-23874	192	5	ph15080973	ph15080973	NOUN
brj-23874	192	6	bennett	bennett	PROPN
brj-23874	192	7	,	,	PUNCT
brj-23874	192	8	t.	t.	NOUN
brj-23874	192	9	m.	m.	NOUN
brj-23874	192	10	,	,	PUNCT
brj-23874	192	11	modna	modna	NOUN
brj-23874	192	12	,	,	PUNCT
brj-23874	192	13	y.	y.	NOUN
brj-23874	192	14	,	,	PUNCT
brj-23874	192	15	and	and	CCONJ
brj-23874	192	16	shah	shah	NOUN
brj-23874	192	17	,	,	PUNCT
brj-23874	192	18	d.	d.	PROPN
brj-23874	192	19	k.	k.	PROPN
brj-23874	192	20	(	(	PUNCT
brj-23874	192	21	2024	2024	NUM
brj-23874	192	22	)	)	PUNCT
brj-23874	192	23	.	.	PUNCT
brj-23874	193	1	“	"	PUNCT
brj-23874	193	2	the	the	DET
brj-23874	193	3	impact	impact	NOUN
brj-23874	193	4	of	of	ADP
brj-23874	193	5	opioid	opioid	ADJ
brj-23874	193	6	drugs	drug	NOUN
brj-23874	193	7	on	on	ADP
brj-23874	193	8	memory	memory	NOUN
brj-23874	193	9	and	and	CCONJ
brj-23874	193	10	other	other	ADJ
brj-23874	193	11	cognitive	cognitive	ADJ
brj-23874	193	12	functions	function	NOUN
brj-23874	193	13	:	:	PUNCT
brj-23874	193	14	a	a	DET
brj-23874	193	15	review	review	NOUN
brj-23874	193	16	,	,	PUNCT
brj-23874	193	17	”	"	PUNCT
brj-23874	193	18	journal	journal	NOUN
brj-23874	193	19	of	of	ADP
brj-23874	193	20	biosciences	bioscience	NOUN
brj-23874	193	21	and	and	CCONJ
brj-23874	193	22	medicines	medicine	NOUN
brj-23874	193	23	12	12	NUM
brj-23874	193	24	,	,	PUNCT
brj-23874	193	25	4	4	NUM
brj-23874	193	26	.	.	X
brj-23874	193	27	doi	doi	NOUN
brj-23874	193	28	:	:	PUNCT
brj-23874	193	29	10.4088	10.4088	NUM
brj-23874	193	30	/	/	SYM
brj-23874	193	31	pcc.11m01326	pcc.11m01326	NOUN
brj-23874	193	32	chi	chi	PROPN
brj-23874	193	33	,	,	PUNCT
brj-23874	193	34	s.	s.	PROPN
brj-23874	193	35	c.	c.	PROPN
brj-23874	193	36	h.	h.	PROPN
brj-23874	193	37	,	,	PUNCT
brj-23874	193	38	and	and	CCONJ
brj-23874	193	39	jun	jun	PROPN
brj-23874	193	40	,	,	PUNCT
brj-23874	193	41	h.	h.	PROPN
brj-23874	193	42	w.	w.	PROPN
brj-23874	193	43	(	(	PUNCT
brj-23874	193	44	1990	1990	NUM
brj-23874	193	45	)	)	PUNCT
brj-23874	193	46	.	.	PUNCT
brj-23874	194	1	“	"	PUNCT
brj-23874	194	2	anti	anti	ADJ
brj-23874	194	3	-	-	ADJ
brj-23874	194	4	inflammatory	inflammatory	ADJ
brj-23874	194	5	activity	activity	NOUN
brj-23874	194	6	of	of	ADP
brj-23874	194	7	ketoprofen	ketoprofen	NOUN
brj-23874	194	8	gel	gel	NOUN
brj-23874	194	9	on	on	ADP
brj-23874	194	10	carrageenan	carrageenan	NOUN
brj-23874	194	11	-	-	PUNCT
brj-23874	194	12	induced	induce	VERB
brj-23874	194	13	paw	paw	NOUN
brj-23874	194	14	edema	edema	NOUN
brj-23874	194	15	in	in	ADP
brj-23874	194	16	rats	rat	NOUN
brj-23874	194	17	,	,	PUNCT
brj-23874	194	18	”	"	PUNCT
brj-23874	194	19	journal	journal	NOUN
brj-23874	194	20	of	of	ADP
brj-23874	194	21	pharmaceutical	pharmaceutical	PROPN
brj-23874	194	22	sciences	science	NOUN
brj-23874	194	23	79	79	NUM
brj-23874	194	24	,	,	PUNCT
brj-23874	194	25	974	974	NUM
brj-23874	194	26	-	-	SYM
brj-23874	194	27	977	977	NUM
brj-23874	194	28	.	.	PUNCT
brj-23874	195	1	doi	doi	NOUN
brj-23874	195	2	:	:	PUNCT
brj-23874	195	3	10.1002	10.1002	NUM
brj-23874	195	4	/	/	SYM
brj-23874	195	5	jps.2600791106	jps.2600791106	NUM
brj-23874	195	6	clinkard	clinkard	NOUN
brj-23874	195	7	,	,	PUNCT
brj-23874	195	8	d.	d.	PROPN
brj-23874	195	9	,	,	PUNCT
brj-23874	195	10	buckley	buckley	PROPN
brj-23874	195	11	,	,	PUNCT
brj-23874	195	12	n.	n.	PROPN
brj-23874	195	13	,	,	PUNCT
brj-23874	195	14	diatchenko	diatchenko	PROPN
brj-23874	195	15	,	,	PUNCT
brj-23874	195	16	l.	l.	PROPN
brj-23874	195	17	,	,	PUNCT
brj-23874	195	18	and	and	CCONJ
brj-23874	195	19	ghasemlou	ghasemlou	ADJ
brj-23874	195	20	,	,	PUNCT
brj-23874	195	21	n.	n.	PROPN
brj-23874	195	22	(	(	PUNCT
brj-23874	195	23	2024	2024	NUM
brj-23874	195	24	)	)	PUNCT
brj-23874	195	25	.	.	PUNCT
brj-23874	196	1	“	"	PUNCT
brj-23874	196	2	the	the	DET
brj-23874	196	3	role	role	NOUN
brj-23874	196	4	of	of	ADP
brj-23874	196	5	acute	acute	ADJ
brj-23874	196	6	inflammation	inflammation	NOUN
brj-23874	196	7	in	in	ADP
brj-23874	196	8	pain	pain	NOUN
brj-23874	196	9	resolution	resolution	NOUN
brj-23874	196	10	is	be	AUX
brj-23874	196	11	time	time	NOUN
brj-23874	196	12	to	to	PART
brj-23874	196	13	rethink	rethink	VERB
brj-23874	196	14	the	the	DET
brj-23874	196	15	use	use	NOUN
brj-23874	196	16	of	of	ADP
brj-23874	196	17	routine	routine	ADJ
brj-23874	196	18	antiinflammatories	antiinflammatorie	NOUN
brj-23874	196	19	in	in	ADP
brj-23874	196	20	surgical	surgical	ADJ
brj-23874	196	21	practice	practice	NOUN
brj-23874	196	22	,	,	PUNCT
brj-23874	196	23	”	"	PUNCT
brj-23874	196	24	can	can	AUX
brj-23874	196	25	.	.	PUNCT
brj-23874	197	1	j.	j.	PROPN
brj-23874	197	2	anesth./j	anesth./j	PROPN
brj-23874	197	3	.	.	PROPN
brj-23874	197	4	can	can	AUX
brj-23874	197	5	.	.	PUNCT
brj-23874	198	1	anesth	anesth	PROPN
brj-23874	198	2	.	.	PROPN
brj-23874	199	1	71	71	NUM
brj-23874	199	2	,	,	PUNCT
brj-23874	199	3	1349	1349	NUM
brj-23874	199	4	-	-	SYM
brj-23874	199	5	1352	1352	NUM
brj-23874	199	6	.	.	PUNCT
brj-23874	200	1	doi	doi	NOUN
brj-23874	200	2	:	:	PUNCT
brj-23874	200	3	10.1007	10.1007	NUM
brj-23874	200	4	/	/	SYM
brj-23874	200	5	s12630	s12630	NOUN
brj-23874	200	6	-	-	PUNCT
brj-23874	200	7	024	024	NUM
brj-23874	200	8	-	-	PUNCT
brj-23874	200	9	02837	02837	NUM
brj-23874	200	10	-	-	SYM
brj-23874	200	11	8	8	NUM
brj-23874	200	12	gordon	gordon	PROPN
brj-23874	200	13	,	,	PUNCT
brj-23874	200	14	d.	d.	PROPN
brj-23874	200	15	b.	b.	PROPN
brj-23874	200	16	,	,	PUNCT
brj-23874	200	17	de	de	PROPN
brj-23874	200	18	leon	leon	PROPN
brj-23874	200	19	-	-	PUNCT
brj-23874	200	20	casasola	casasola	PROPN
brj-23874	200	21	,	,	PUNCT
brj-23874	200	22	o.	o.	PROPN
brj-23874	200	23	a.	a.	PROPN
brj-23874	200	24	,	,	PUNCT
brj-23874	200	25	wu	wu	PROPN
brj-23874	200	26	,	,	PUNCT
brj-23874	200	27	c.	c.	PROPN
brj-23874	200	28	l.	l.	PROPN
brj-23874	200	29	,	,	PUNCT
brj-23874	200	30	sluka	sluka	PROPN
brj-23874	200	31	,	,	PUNCT
brj-23874	200	32	k.	k.	PROPN
brj-23874	200	33	a.	a.	PROPN
brj-23874	200	34	,	,	PUNCT
brj-23874	200	35	brennan	brennan	PROPN
brj-23874	200	36	,	,	PUNCT
brj-23874	200	37	t.	t.	PROPN
brj-23874	200	38	j.	j.	PROPN
brj-23874	200	39	,	,	PUNCT
brj-23874	200	40	and	and	CCONJ
brj-23874	200	41	chou	chou	NOUN
brj-23874	200	42	,	,	PUNCT
brj-23874	200	43	r.	r.	PROPN
brj-23874	200	44	(	(	PUNCT
brj-23874	200	45	2016	2016	NUM
brj-23874	200	46	)	)	PUNCT
brj-23874	200	47	.	.	PUNCT
brj-23874	201	1	“	"	PUNCT
brj-23874	201	2	research	research	NOUN
brj-23874	201	3	gaps	gap	NOUN
brj-23874	201	4	in	in	ADP
brj-23874	201	5	practice	practice	NOUN
brj-23874	201	6	guidelines	guideline	NOUN
brj-23874	201	7	for	for	ADP
brj-23874	201	8	acute	acute	ADJ
brj-23874	201	9	postoperative	postoperative	ADJ
brj-23874	201	10	pain	pain	NOUN
brj-23874	201	11	management	management	NOUN
brj-23874	201	12	in	in	ADP
brj-23874	201	13	adults	adult	NOUN
brj-23874	201	14	,	,	PUNCT
brj-23874	201	15	findings	finding	NOUN
brj-23874	201	16	from	from	ADP
brj-23874	201	17	a	a	DET
brj-23874	201	18	review	review	NOUN
brj-23874	201	19	of	of	ADP
brj-23874	201	20	the	the	DET
brj-23874	201	21	evidence	evidence	NOUN
brj-23874	201	22	for	for	ADP
brj-23874	201	23	an	an	DET
brj-23874	201	24	american	american	ADJ
brj-23874	201	25	pain	pain	PROPN
brj-23874	201	26	society	society	PROPN
brj-23874	201	27	clinical	clinical	ADJ
brj-23874	201	28	practice	practice	NOUN
brj-23874	201	29	guideline	guideline	NOUN
brj-23874	201	30	,	,	PUNCT
brj-23874	201	31	”	"	PUNCT
brj-23874	201	32	j.	j.	PROPN
brj-23874	201	33	pain	pain	PROPN
brj-23874	201	34	17(2	17(2	NUM
brj-23874	201	35	)	)	PUNCT
brj-23874	201	36	,	,	PUNCT
brj-23874	201	37	158	158	NUM
brj-23874	201	38	-	-	SYM
brj-23874	201	39	166	166	NUM
brj-23874	201	40	.	.	PUNCT
brj-23874	202	1	doi	doi	NOUN
brj-23874	202	2	:	:	PUNCT
brj-23874	202	3	10.1016	10.1016	NUM
brj-23874	202	4	/	/	SYM
brj-23874	202	5	j.jpain.2015.10.023	j.jpain.2015.10.023	PROPN
brj-23874	202	6	international	international	ADJ
brj-23874	202	7	association	association	NOUN
brj-23874	202	8	for	for	ADP
brj-23874	202	9	the	the	DET
brj-23874	202	10	study	study	NOUN
brj-23874	202	11	of	of	ADP
brj-23874	202	12	pain	pain	NOUN
brj-23874	202	13	(	(	PUNCT
brj-23874	202	14	2012	2012	NUM
brj-23874	202	15	)	)	PUNCT
brj-23874	202	16	.	.	PUNCT
brj-23874	203	1	“	"	PUNCT
brj-23874	203	2	unrelieved	unrelieved	ADJ
brj-23874	203	3	pain	pain	NOUN
brj-23874	203	4	is	be	AUX
brj-23874	203	5	a	a	DET
brj-23874	203	6	major	major	ADJ
brj-23874	203	7	global	global	ADJ
brj-23874	203	8	healthcare	healthcare	PROPN
brj-23874	203	9	problem	problem	NOUN
brj-23874	203	10	,	,	PUNCT
brj-23874	203	11	”	"	PUNCT
brj-23874	203	12	primary	primary	ADJ
brj-23874	203	13	care	care	NOUN
brj-23874	203	14	companion	companion	NOUN
brj-23874	203	15	cns	cns	NOUN
brj-23874	203	16	disorders	disorder	NOUN
brj-23874	203	17	14	14	NUM
brj-23874	203	18	.	.	PUNCT
brj-23874	204	1	meybodi	meybodi	NOUN
brj-23874	204	2	,	,	PUNCT
brj-23874	204	3	m.	m.	NOUN
brj-23874	204	4	s.	s.	PROPN
brj-23874	204	5	k.	k.	PROPN
brj-23874	204	6	(	(	PUNCT
brj-23874	204	7	2020	2020	NUM
brj-23874	204	8	)	)	PUNCT
brj-23874	204	9	.	.	PUNCT
brj-23874	205	1	a	a	DET
brj-23874	205	2	review	review	NOUN
brj-23874	205	3	on	on	ADP
brj-23874	205	4	pharmacological	pharmacological	ADJ
brj-23874	205	5	activities	activity	NOUN
brj-23874	205	6	of	of	ADP
brj-23874	205	7	citrullus	citrullus	PROPN
brj-23874	205	8	colocynthis	colocynthis	PROPN
brj-23874	205	9	(	(	PUNCT
brj-23874	205	10	l.	l.	PROPN
brj-23874	205	11	)	)	PUNCT
brj-23874	205	12	schrad	schrad	NOUN
brj-23874	205	13	.	.	PUNCT
brj-23874	206	1	asian	asian	PROPN
brj-23874	206	2	j	j	PROPN
brj-23874	206	3	res	res	PROPN
brj-23874	206	4	rep	rep	PROPN
brj-23874	206	5	endocrinol	endocrinol	NOUN
brj-23874	206	6	,	,	PUNCT
brj-23874	206	7	25	25	NUM
brj-23874	206	8	,	,	PUNCT
brj-23874	206	9	34	34	NUM
brj-23874	206	10	.	.	PUNCT
brj-23874	207	1	article	article	PROPN
brj-23874	207	2	no.ajrre.57333	no.ajrre.57333	PROPN
brj-23874	207	3	khan	khan	PROPN
brj-23874	207	4	,	,	PUNCT
brj-23874	207	5	h.	h.	PROPN
brj-23874	207	6	,	,	PUNCT
brj-23874	207	7	pervaiz	pervaiz	PROPN
brj-23874	207	8	,	,	PUNCT
brj-23874	207	9	a.	a.	NOUN
brj-23874	207	10	,	,	PUNCT
brj-23874	207	11	intagliata	intagliata	PROPN
brj-23874	207	12	,	,	PUNCT
brj-23874	207	13	s.	s.	PROPN
brj-23874	207	14	,	,	PUNCT
brj-23874	207	15	das	das	PROPN
brj-23874	207	16	,	,	PUNCT
brj-23874	207	17	n.	n.	NOUN
brj-23874	207	18	,	,	PUNCT
brj-23874	207	19	venkata	venkata	PROPN
brj-23874	207	20	,	,	PUNCT
brj-23874	207	21	k.	k.	PROPN
brj-23874	207	22	c.	c.	PROPN
brj-23874	207	23	n.	n.	PROPN
brj-23874	207	24	,	,	PUNCT
brj-23874	207	25	atanasov	atanasov	PROPN
brj-23874	207	26	,	,	PUNCT
brj-23874	207	27	a.	a.	NOUN
brj-23874	207	28	g.	g.	PROPN
brj-23874	207	29	,	,	PUNCT
brj-23874	207	30	najda	najda	PROPN
brj-23874	207	31	,	,	PUNCT
brj-23874	207	32	a.	a.	NOUN
brj-23874	207	33	,	,	PUNCT
brj-23874	207	34	nabavi	nabavi	PROPN
brj-23874	207	35	,	,	PUNCT
brj-23874	207	36	s.	s.	PROPN
brj-23874	207	37	m.	m.	PROPN
brj-23874	207	38	,	,	PUNCT
brj-23874	207	39	wang	wang	PROPN
brj-23874	207	40	,	,	PUNCT
brj-23874	207	41	d.	d.	PROPN
brj-23874	207	42	,	,	PUNCT
brj-23874	207	43	pittala	pittala	NOUN
brj-23874	207	44	,	,	PUNCT
brj-23874	207	45	v.	v.	ADV
brj-23874	207	46	,	,	PUNCT
brj-23874	207	47	and	and	CCONJ
brj-23874	207	48	bishayee	bishayee	NOUN
brj-23874	207	49	,	,	PUNCT
brj-23874	207	50	a.	a.	NOUN
brj-23874	207	51	(	(	PUNCT
brj-23874	207	52	2020	2020	NUM
brj-23874	207	53	)	)	PUNCT
brj-23874	207	54	.	.	PUNCT
brj-23874	208	1	“	"	PUNCT
brj-23874	208	2	the	the	DET
brj-23874	208	3	analgesic	analgesic	ADJ
brj-23874	208	4	potential	potential	NOUN
brj-23874	208	5	of	of	ADP
brj-23874	208	6	glycosides	glycoside	NOUN
brj-23874	208	7	derived	derive	VERB
brj-23874	208	8	from	from	ADP
brj-23874	208	9	medicinal	medicinal	ADJ
brj-23874	208	10	plants	plant	NOUN
brj-23874	208	11	,	,	PUNCT
brj-23874	208	12	”	"	PUNCT
brj-23874	208	13	daru	daru	PROPN
brj-23874	208	14	j	j	PROPN
brj-23874	208	15	of	of	ADP
brj-23874	208	16	pharmaceutical	pharmaceutical	PROPN
brj-23874	208	17	science	science	NOUN
brj-23874	208	18	28	28	NUM
brj-23874	208	19	,	,	PUNCT
brj-23874	208	20	387	387	NUM
brj-23874	208	21	-	-	SYM
brj-23874	208	22	401	401	NUM
brj-23874	208	23	.	.	PUNCT
brj-23874	209	1	doi	doi	NOUN
brj-23874	209	2	:	:	PUNCT
brj-23874	209	3	10.1007	10.1007	NUM
brj-23874	209	4	/	/	SYM
brj-23874	209	5	s40199	s40199	NOUN
brj-23874	209	6	-	-	PUNCT
brj-23874	209	7	019	019	NUM
brj-23874	209	8	-	-	PUNCT
brj-23874	209	9	00319	00319	NUM
brj-23874	209	10	-	-	PUNCT
brj-23874	209	11	7	7	NUM
brj-23874	209	12	kim	kim	PROPN
brj-23874	209	13	,	,	PUNCT
brj-23874	209	14	e.	e.	PROPN
brj-23874	209	15	,	,	PUNCT
brj-23874	209	16	cui	cui	PROPN
brj-23874	209	17	,	,	PUNCT
brj-23874	209	18	j.	j.	PROPN
brj-23874	209	19	,	,	PUNCT
brj-23874	209	20	zhang	zhang	PROPN
brj-23874	209	21	,	,	PUNCT
brj-23874	209	22	g.	g.	PROPN
brj-23874	209	23	,	,	PUNCT
brj-23874	209	24	and	and	CCONJ
brj-23874	209	25	lee	lee	PROPN
brj-23874	209	26	,	,	PUNCT
brj-23874	209	27	y.	y.	PROPN
brj-23874	209	28	(	(	PUNCT
brj-23874	209	29	2022	2022	NUM
brj-23874	209	30	)	)	PUNCT
brj-23874	209	31	.	.	PUNCT
brj-23874	210	1	“	"	PUNCT
brj-23874	210	2	physiological	physiological	ADJ
brj-23874	210	3	effects	effect	NOUN
brj-23874	210	4	of	of	ADP
brj-23874	210	5	green	green	ADJ
brj-23874	210	6	-	-	PUNCT
brj-23874	210	7	colored	color	VERB
brj-23874	210	8	food	food	NOUN
brj-23874	210	9	-	-	PUNCT
brj-23874	210	10	derived	derive	VERB
brj-23874	210	11	bioactive	bioactive	ADJ
brj-23874	210	12	compounds	compound	NOUN
brj-23874	210	13	on	on	ADP
brj-23874	210	14	cardiovascular	cardiovascular	ADJ
brj-23874	210	15	and	and	CCONJ
brj-23874	210	16	metabolic	metabolic	NOUN
brj-23874	210	17	diseases	disease	NOUN
brj-23874	210	18	,	,	PUNCT
brj-23874	210	19	”	"	PUNCT
brj-23874	210	20	applied	apply	VERB
brj-23874	210	21	sciences	science	NOUN
brj-23874	210	22	12(4	12(4	NUM
brj-23874	210	23	)	)	PUNCT
brj-23874	210	24	,	,	PUNCT
brj-23874	210	25	article	article	NOUN
brj-23874	210	26	1879	1879	NUM
brj-23874	210	27	.	.	PUNCT
brj-23874	211	1	doi	doi	NOUN
brj-23874	211	2	:	:	PUNCT
brj-23874	211	3	10.3390	10.3390	NUM
brj-23874	211	4	/	/	SYM
brj-23874	211	5	app12041879	app12041879	NOUN
brj-23874	211	6	peer	peer	NOUN
brj-23874	211	7	-	-	PUNCT
brj-23874	211	8	reviewed	review	VERB
brj-23874	211	9	article	article	NOUN
brj-23874	211	10	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	211	11	zhu	zhu	PROPN
brj-23874	211	12	et	et	PROPN
brj-23874	211	13	al	al	PROPN
brj-23874	211	14	.	.	PROPN
brj-23874	212	1	(	(	PUNCT
brj-23874	212	2	2026	2026	NUM
brj-23874	212	3	)	)	PUNCT
brj-23874	212	4	.	.	PUNCT
brj-23874	213	1	“	"	PUNCT
brj-23874	213	2	pain	pain	NOUN
brj-23874	213	3	control	control	NOUN
brj-23874	213	4	with	with	ADP
brj-23874	213	5	seed	seed	NOUN
brj-23874	213	6	extract	extract	NOUN
brj-23874	213	7	,	,	PUNCT
brj-23874	213	8	”	"	PUNCT
brj-23874	213	9	bioresources	bioresource	NOUN
brj-23874	213	10	21(1	21(1	NUM
brj-23874	213	11	)	)	PUNCT
brj-23874	213	12	,	,	PUNCT
brj-23874	213	13	116	116	NUM
brj-23874	213	14	-	-	SYM
brj-23874	213	15	127	127	NUM
brj-23874	213	16	.	.	PUNCT
brj-23874	214	1	126	126	NUM
brj-23874	214	2	li	li	PROPN
brj-23874	214	3	,	,	PUNCT
brj-23874	214	4	q.	q.	PROPN
brj-23874	214	5	y.	y.	PROPN
brj-23874	214	6	,	,	PUNCT
brj-23874	214	7	munawar	munawar	PROPN
brj-23874	214	8	,	,	PUNCT
brj-23874	214	9	m.	m.	NOUN
brj-23874	214	10	,	,	PUNCT
brj-23874	214	11	saeed	saeed	PROPN
brj-23874	214	12	,	,	PUNCT
brj-23874	214	13	m.	m.	NOUN
brj-23874	214	14	,	,	PUNCT
brj-23874	214	15	shen	shen	PROPN
brj-23874	214	16	,	,	PUNCT
brj-23874	214	17	j.	j.	PROPN
brj-23874	214	18	q.	q.	PROPN
brj-23874	214	19	,	,	PUNCT
brj-23874	214	20	khan	khan	PROPN
brj-23874	214	21	,	,	PUNCT
brj-23874	214	22	m.	m.	PROPN
brj-23874	214	23	s.	s.	PROPN
brj-23874	214	24	,	,	PUNCT
brj-23874	214	25	noreen	noreen	PROPN
brj-23874	214	26	,	,	PUNCT
brj-23874	214	27	s.	s.	PROPN
brj-23874	214	28	,	,	PUNCT
brj-23874	214	29	alagawany	alagawany	NOUN
brj-23874	214	30	,	,	PUNCT
brj-23874	214	31	m.	m.	NOUN
brj-23874	214	32	,	,	PUNCT
brj-23874	214	33	naveed	naveed	PROPN
brj-23874	214	34	,	,	PUNCT
brj-23874	214	35	m.	m.	NOUN
brj-23874	214	36	,	,	PUNCT
brj-23874	214	37	madni	madni	NOUN
brj-23874	214	38	,	,	PUNCT
brj-23874	214	39	a.	a.	NOUN
brj-23874	214	40	,	,	PUNCT
brj-23874	214	41	and	and	CCONJ
brj-23874	214	42	li	li	PROPN
brj-23874	214	43	,	,	PUNCT
brj-23874	214	44	c.	c.	PROPN
brj-23874	214	45	x.	x.	PROPN
brj-23874	214	46	(	(	PUNCT
brj-23874	214	47	2022	2022	NUM
brj-23874	214	48	)	)	PUNCT
brj-23874	214	49	.	.	PUNCT
brj-23874	215	1	“	"	PUNCT
brj-23874	215	2	citrullus	citrullus	VERB
brj-23874	215	3	colocynthis	colocynthis	PROPN
brj-23874	215	4	(	(	PUNCT
brj-23874	215	5	l.	l.	PROPN
brj-23874	215	6	)	)	PUNCT
brj-23874	215	7	schrad	schrad	NOUN
brj-23874	215	8	(	(	PUNCT
brj-23874	215	9	bitter	bitter	ADJ
brj-23874	215	10	apple	apple	NOUN
brj-23874	215	11	fruit	fruit	NOUN
brj-23874	215	12	):	):	PUNCT
brj-23874	215	13	promising	promise	VERB
brj-23874	215	14	traditional	traditional	ADJ
brj-23874	215	15	uses	use	NOUN
brj-23874	215	16	,	,	PUNCT
brj-23874	215	17	pharmacological	pharmacological	ADJ
brj-23874	215	18	effects	effect	NOUN
brj-23874	215	19	,	,	PUNCT
brj-23874	215	20	aspects	aspect	NOUN
brj-23874	215	21	,	,	PUNCT
brj-23874	215	22	and	and	CCONJ
brj-23874	215	23	potential	potential	ADJ
brj-23874	215	24	applications	application	NOUN
brj-23874	215	25	,	,	PUNCT
brj-23874	215	26	”	"	PUNCT
brj-23874	215	27	frontiers	frontier	NOUN
brj-23874	215	28	in	in	ADP
brj-23874	215	29	pharmacology	pharmacology	NOUN
brj-23874	215	30	12	12	NUM
brj-23874	215	31	,	,	PUNCT
brj-23874	215	32	article	article	NOUN
brj-23874	215	33	791049	791049	NUM
brj-23874	215	34	.	.	PUNCT
brj-23874	216	1	doi	doi	NOUN
brj-23874	216	2	:	:	PUNCT
brj-23874	216	3	10.3389	10.3389	NUM
brj-23874	216	4	/	/	SYM
brj-23874	216	5	fphar.2021.791049	fphar.2021.791049	VERB
brj-23874	216	6	maisetta	maisetta	ADJ
brj-23874	216	7	,	,	PUNCT
brj-23874	216	8	g.	g.	PROPN
brj-23874	216	9	,	,	PUNCT
brj-23874	216	10	batoni	batoni	PROPN
brj-23874	216	11	,	,	PUNCT
brj-23874	216	12	g.	g.	PROPN
brj-23874	216	13	,	,	PUNCT
brj-23874	216	14	caboni	caboni	PROPN
brj-23874	216	15	,	,	PUNCT
brj-23874	216	16	p.	p.	PROPN
brj-23874	216	17	,	,	PUNCT
brj-23874	216	18	esin	esin	PROPN
brj-23874	216	19	,	,	PUNCT
brj-23874	216	20	s.	s.	PROPN
brj-23874	216	21	,	,	PUNCT
brj-23874	216	22	rinaldi	rinaldi	PROPN
brj-23874	216	23	,	,	PUNCT
brj-23874	216	24	a.c	a.c	PROPN
brj-23874	216	25	.	.	PROPN
brj-23874	216	26	,	,	PUNCT
brj-23874	216	27	and	and	CCONJ
brj-23874	216	28	zucca	zucca	NOUN
brj-23874	216	29	,	,	PUNCT
brj-23874	216	30	p.	p.	NOUN
brj-23874	216	31	(	(	PUNCT
brj-23874	216	32	2019	2019	NUM
brj-23874	216	33	)	)	PUNCT
brj-23874	216	34	.	.	PUNCT
brj-23874	217	1	“	"	PUNCT
brj-23874	217	2	tannin	tannin	NOUN
brj-23874	217	3	profile	profile	NOUN
brj-23874	217	4	,	,	PUNCT
brj-23874	217	5	antioxidant	antioxidant	ADJ
brj-23874	217	6	properties	property	NOUN
brj-23874	217	7	,	,	PUNCT
brj-23874	217	8	and	and	CCONJ
brj-23874	217	9	antimicrobial	antimicrobial	ADJ
brj-23874	217	10	activity	activity	NOUN
brj-23874	217	11	of	of	ADP
brj-23874	217	12	extracts	extract	NOUN
brj-23874	217	13	from	from	ADP
brj-23874	217	14	two	two	NUM
brj-23874	217	15	mediterranean	mediterranean	ADJ
brj-23874	217	16	species	specie	NOUN
brj-23874	217	17	of	of	ADP
brj-23874	217	18	parasitic	parasitic	ADJ
brj-23874	217	19	plant	plant	NOUN
brj-23874	217	20	cytinus	cytinus	NOUN
brj-23874	217	21	,	,	PUNCT
brj-23874	217	22	”	"	PUNCT
brj-23874	217	23	bmc	bmc	PROPN
brj-23874	217	24	complement	complement	NOUN
brj-23874	217	25	altern	altern	NOUN
brj-23874	217	26	.	.	PUNCT
brj-23874	218	1	med	med	PROPN
brj-23874	218	2	.	.	PROPN
brj-23874	219	1	19	19	NUM
brj-23874	219	2	,	,	PUNCT
brj-23874	219	3	82	82	NUM
brj-23874	219	4	.	.	PUNCT
brj-23874	219	5	doi	doi	NOUN
brj-23874	219	6	:	:	PUNCT
brj-23874	219	7	10.1186	10.1186	NUM
brj-23874	219	8	/	/	SYM
brj-23874	219	9	s12906	s12906	VERB
brj-23874	219	10	-	-	PUNCT
brj-23874	219	11	019	019	NUM
brj-23874	219	12	-	-	PUNCT
brj-23874	219	13	2487	2487	NUM
brj-23874	219	14	-	-	SYM
brj-23874	219	15	7	7	NUM
brj-23874	219	16	mergia	mergia	NOUN
brj-23874	219	17	,	,	PUNCT
brj-23874	219	18	e.	e.	PROPN
brj-23874	219	19	,	,	PUNCT
brj-23874	219	20	shibeshi	shibeshi	PROPN
brj-23874	219	21	,	,	PUNCT
brj-23874	219	22	w.	w.	PROPN
brj-23874	219	23	,	,	PUNCT
brj-23874	219	24	terefe	terefe	PROPN
brj-23874	219	25	,	,	PUNCT
brj-23874	219	26	g.	g.	PROPN
brj-23874	219	27	,	,	PUNCT
brj-23874	219	28	and	and	CCONJ
brj-23874	219	29	teklehaymanot	teklehaymanot	ADV
brj-23874	219	30	,	,	PUNCT
brj-23874	219	31	t.	t.	PROPN
brj-23874	219	32	(	(	PUNCT
brj-23874	219	33	2016	2016	NUM
brj-23874	219	34	)	)	PUNCT
brj-23874	219	35	.	.	PUNCT
brj-23874	220	1	“	"	PUNCT
brj-23874	220	2	antitrypanosomally	antitrypanosomally	ADV
brj-23874	220	3	activity	activity	NOUN
brj-23874	220	4	of	of	ADP
brj-23874	220	5	verbascum	verbascum	NOUN
brj-23874	220	6	sinaiticum	sinaiticum	PROPN
brj-23874	220	7	benth	benth	PROPN
brj-23874	220	8	.	.	PUNCT
brj-23874	221	1	(	(	PUNCT
brj-23874	221	2	scrophulariaceae	scrophulariaceae	PROPN
brj-23874	221	3	)	)	PUNCT
brj-23874	221	4	against	against	ADP
brj-23874	221	5	trypanosoma	trypanosoma	PROPN
brj-23874	221	6	congolense	congolense	NOUN
brj-23874	221	7	isolates	isolate	NOUN
brj-23874	221	8	,	,	PUNCT
brj-23874	221	9	”	"	PUNCT
brj-23874	221	10	bmc	bmc	X
brj-23874	221	11	complementary	complementary	ADJ
brj-23874	221	12	and	and	CCONJ
brj-23874	221	13	alternative	alternative	ADJ
brj-23874	221	14	medicine	medicine	NOUN
brj-23874	221	15	16	16	NUM
brj-23874	221	16	,	,	PUNCT
brj-23874	221	17	362	362	NUM
brj-23874	221	18	.	.	PUNCT
brj-23874	222	1	doi	doi	NOUN
brj-23874	222	2	:	:	PUNCT
brj-23874	222	3	10.1186	10.1186	NUM
brj-23874	222	4	/	/	SYM
brj-23874	222	5	s12906	s12906	VERB
brj-23874	222	6	-	-	PUNCT
brj-23874	222	7	016	016	NUM
brj-23874	222	8	-	-	PUNCT
brj-23874	222	9	1346	1346	NUM
brj-23874	222	10	-	-	PUNCT
brj-23874	222	11	z	z	NOUN
brj-23874	222	12	murray	murray	NOUN
brj-23874	222	13	,	,	PUNCT
brj-23874	222	14	c.	c.	PROPN
brj-23874	222	15	b.	b.	PROPN
brj-23874	222	16	,	,	PUNCT
brj-23874	222	17	de	de	PROPN
brj-23874	222	18	la	la	PROPN
brj-23874	222	19	vega	vega	PROPN
brj-23874	222	20	,	,	PUNCT
brj-23874	222	21	r.	r.	PROPN
brj-23874	222	22	,	,	PUNCT
brj-23874	222	23	murphy	murphy	PROPN
brj-23874	222	24	,	,	PUNCT
brj-23874	222	25	l.	l.	PROPN
brj-23874	222	26	k.	k.	PROPN
brj-23874	222	27	,	,	PUNCT
brj-23874	222	28	kashikar	kashikar	PROPN
brj-23874	222	29	-	-	PUNCT
brj-23874	222	30	zuck	zuck	PROPN
brj-23874	222	31	,	,	PUNCT
brj-23874	222	32	s.	s.	PROPN
brj-23874	222	33	,	,	PUNCT
brj-23874	222	34	and	and	CCONJ
brj-23874	222	35	palermo	palermo	NOUN
brj-23874	222	36	,	,	PUNCT
brj-23874	222	37	t.	t.	NOUN
brj-23874	222	38	m.	m.	NOUN
brj-23874	222	39	(	(	PUNCT
brj-23874	222	40	2022	2022	NUM
brj-23874	222	41	)	)	PUNCT
brj-23874	222	42	.	.	PUNCT
brj-23874	223	1	“	"	PUNCT
brj-23874	223	2	the	the	DET
brj-23874	223	3	prevalence	prevalence	NOUN
brj-23874	223	4	of	of	ADP
brj-23874	223	5	chronic	chronic	ADJ
brj-23874	223	6	pain	pain	NOUN
brj-23874	223	7	in	in	ADP
brj-23874	223	8	young	young	ADJ
brj-23874	223	9	adults	adult	NOUN
brj-23874	223	10	,	,	PUNCT
brj-23874	223	11	a	a	DET
brj-23874	223	12	systematic	systematic	ADJ
brj-23874	223	13	review	review	NOUN
brj-23874	223	14	and	and	CCONJ
brj-23874	223	15	meta	meta	ADJ
brj-23874	223	16	-	-	PUNCT
brj-23874	223	17	analysis	analysis	NOUN
brj-23874	223	18	,	,	PUNCT
brj-23874	223	19	”	"	PUNCT
brj-23874	223	20	pain	pain	NOUN
brj-23874	223	21	163(9	163(9	NUM
brj-23874	223	22	)	)	PUNCT
brj-23874	223	23	,	,	PUNCT
brj-23874	223	24	e972	e972	PROPN
brj-23874	223	25	-	-	PUNCT
brj-23874	223	26	e984	e984	PROPN
brj-23874	223	27	.	.	PUNCT
brj-23874	223	28	doi	doi	PROPN
brj-23874	223	29	:	:	PUNCT
brj-23874	223	30	10.1097	10.1097	NUM
brj-23874	223	31	/	/	SYM
brj-23874	223	32	j.pain.0000000000002541	j.pain.0000000000002541	PROPN
brj-23874	223	33	national	national	PROPN
brj-23874	223	34	research	research	PROPN
brj-23874	223	35	council	council	PROPN
brj-23874	223	36	(	(	PUNCT
brj-23874	223	37	us	us	PROPN
brj-23874	223	38	)	)	PUNCT
brj-23874	223	39	committee	committee	NOUN
brj-23874	223	40	for	for	ADP
brj-23874	223	41	the	the	DET
brj-23874	223	42	update	update	NOUN
brj-23874	223	43	of	of	ADP
brj-23874	223	44	the	the	DET
brj-23874	223	45	guide	guide	NOUN
brj-23874	223	46	for	for	ADP
brj-23874	223	47	the	the	DET
brj-23874	223	48	care	care	NOUN
brj-23874	223	49	and	and	CCONJ
brj-23874	223	50	use	use	NOUN
brj-23874	223	51	of	of	ADP
brj-23874	223	52	laboratory	laboratory	NOUN
brj-23874	223	53	animals	animal	NOUN
brj-23874	223	54	(	(	PUNCT
brj-23874	223	55	2024	2024	NUM
brj-23874	223	56	)	)	PUNCT
brj-23874	223	57	.	.	PUNCT
brj-23874	224	1	guide	guide	VERB
brj-23874	224	2	for	for	ADP
brj-23874	224	3	the	the	DET
brj-23874	224	4	care	care	NOUN
brj-23874	224	5	and	and	CCONJ
brj-23874	224	6	use	use	NOUN
brj-23874	224	7	of	of	ADP
brj-23874	224	8	laboratory	laboratory	NOUN
brj-23874	224	9	animals	animal	NOUN
brj-23874	224	10	,	,	PUNCT
brj-23874	224	11	8th	8th	ADJ
brj-23874	224	12	edition	edition	NOUN
brj-23874	224	13	,	,	PUNCT
brj-23874	224	14	national	national	PROPN
brj-23874	224	15	academies	academies	PROPN
brj-23874	224	16	press	press	PROPN
brj-23874	224	17	,	,	PUNCT
brj-23874	224	18	washington	washington	PROPN
brj-23874	224	19	,	,	PUNCT
brj-23874	224	20	d.c	d.c	PROPN
brj-23874	224	21	.	.	PROPN
brj-23874	224	22	,	,	PUNCT
brj-23874	224	23	usa	usa	PROPN
brj-23874	224	24	.	.	PROPN
brj-23874	224	25	doi	doi	PROPN
brj-23874	224	26	:	:	PUNCT
brj-23874	224	27	10.17226/12910	10.17226/12910	NUM
brj-23874	224	28	olmedo	olmedo	NOUN
brj-23874	224	29	,	,	PUNCT
brj-23874	224	30	d.	d.	PROPN
brj-23874	224	31	a.	a.	PROPN
brj-23874	224	32	,	,	PUNCT
brj-23874	224	33	vasquez	vasquez	PROPN
brj-23874	224	34	,	,	PUNCT
brj-23874	224	35	y.	y.	PROPN
brj-23874	224	36	,	,	PUNCT
brj-23874	224	37	antonio	antonio	PROPN
brj-23874	224	38	morán	morán	PROPN
brj-23874	224	39	,	,	PUNCT
brj-23874	224	40	j.	j.	PROPN
brj-23874	224	41	,	,	PUNCT
brj-23874	224	42	de	de	X
brj-23874	224	43	león	león	PROPN
brj-23874	224	44	,	,	PUNCT
brj-23874	224	45	e.	e.	PROPN
brj-23874	224	46	g.	g.	PROPN
brj-23874	224	47	,	,	PUNCT
brj-23874	224	48	caballero	caballero	PROPN
brj-23874	224	49	-	-	PUNCT
brj-23874	224	50	george	george	PROPN
brj-23874	224	51	,	,	PUNCT
brj-23874	224	52	c.	c.	PROPN
brj-23874	224	53	,	,	PUNCT
brj-23874	224	54	and	and	CCONJ
brj-23874	224	55	solís	solís	NOUN
brj-23874	224	56	,	,	PUNCT
brj-23874	224	57	p.	p.	NOUN
brj-23874	224	58	n.	n.	NOUN
brj-23874	224	59	(	(	PUNCT
brj-23874	224	60	2024	2024	NUM
brj-23874	224	61	)	)	PUNCT
brj-23874	224	62	.	.	PUNCT
brj-23874	225	1	“	"	PUNCT
brj-23874	225	2	understanding	understand	VERB
brj-23874	225	3	the	the	DET
brj-23874	225	4	artemia	artemia	NOUN
brj-23874	225	5	salina	salina	PROPN
brj-23874	225	6	(	(	PUNCT
brj-23874	225	7	brine	brine	PROPN
brj-23874	225	8	shrimp	shrimp	PROPN
brj-23874	225	9	)	)	PUNCT
brj-23874	225	10	test	test	NOUN
brj-23874	225	11	:	:	PUNCT
brj-23874	225	12	pharmacological	pharmacological	ADJ
brj-23874	225	13	significance	significance	NOUN
brj-23874	225	14	and	and	CCONJ
brj-23874	225	15	global	global	ADJ
brj-23874	225	16	impact	impact	NOUN
brj-23874	225	17	,	,	PUNCT
brj-23874	225	18	”	"	PUNCT
brj-23874	225	19	combinatorial	combinatorial	ADJ
brj-23874	225	20	chemistry	chemistry	NOUN
brj-23874	225	21	&	&	CCONJ
brj-23874	225	22	high	high	ADJ
brj-23874	225	23	throughput	throughput	NOUN
brj-23874	225	24	screening	screening	NOUN
brj-23874	225	25	(	(	PUNCT
brj-23874	225	26	cchts	ccht	NOUN
brj-23874	225	27	)	)	PUNCT
brj-23874	225	28	27(4	27(4	NUM
brj-23874	225	29	)	)	PUNCT
brj-23874	225	30	.	.	PUNCT
brj-23874	226	1	doi	doi	NOUN
brj-23874	226	2	:	:	PUNCT
brj-23874	226	3	10.2174/1386207326666230703095928	10.2174/1386207326666230703095928	NUM
brj-23874	226	4	passos	passo	NOUN
brj-23874	226	5	,	,	PUNCT
brj-23874	226	6	f.	f.	PROPN
brj-23874	226	7	r.	r.	PROPN
brj-23874	226	8	,	,	PUNCT
brj-23874	226	9	araújo	araújo	NOUN
brj-23874	226	10	-	-	PUNCT
brj-23874	226	11	filho	filho	PROPN
brj-23874	226	12	,	,	PUNCT
brj-23874	226	13	h.	h.	PROPN
brj-23874	226	14	g.	g.	PROPN
brj-23874	226	15	,	,	PUNCT
brj-23874	226	16	monteiro	monteiro	PROPN
brj-23874	226	17	,	,	PUNCT
brj-23874	226	18	b.	b.	PROPN
brj-23874	226	19	s.	s.	PROPN
brj-23874	226	20	,	,	PUNCT
brj-23874	226	21	shanmugam	shanmugam	PROPN
brj-23874	226	22	,	,	PUNCT
brj-23874	226	23	s.	s.	PROPN
brj-23874	226	24	,	,	PUNCT
brj-23874	226	25	de	de	PROPN
brj-23874	226	26	souza	souza	PROPN
brj-23874	226	27	araújo	araújo	PROPN
brj-23874	226	28	,	,	PUNCT
brj-23874	226	29	a.	a.	NOUN
brj-23874	226	30	a.	a.	PROPN
brj-23874	226	31	,	,	PUNCT
brj-23874	226	32	silva	silva	PROPN
brj-23874	226	33	almeida	almeida	PROPN
brj-23874	226	34	,	,	PUNCT
brj-23874	226	35	j.	j.	PROPN
brj-23874	226	36	r.	r.	PROPN
brj-23874	226	37	d.	d.	PROPN
brj-23874	226	38	,	,	PUNCT
brj-23874	226	39	thangaraj	thangaraj	PROPN
brj-23874	226	40	,	,	PUNCT
brj-23874	226	41	p.	p.	PROPN
brj-23874	226	42	,	,	PUNCT
brj-23874	226	43	quintans	quintans	PROPN
brj-23874	226	44	júnior	júnior	PROPN
brj-23874	226	45	,	,	PUNCT
brj-23874	226	46	l.	l.	PROPN
brj-23874	226	47	j.	j.	PROPN
brj-23874	226	48	,	,	PUNCT
brj-23874	226	49	and	and	CCONJ
brj-23874	226	50	quintans	quintan	NOUN
brj-23874	226	51	,	,	PUNCT
brj-23874	226	52	j.	j.	PROPN
brj-23874	226	53	s.	s.	PROPN
brj-23874	226	54	(	(	PUNCT
brj-23874	226	55	2021	2021	NUM
brj-23874	226	56	)	)	PUNCT
brj-23874	226	57	.	.	PUNCT
brj-23874	227	1	“	"	PUNCT
brj-23874	227	2	anti	anti	ADJ
brj-23874	227	3	-	-	ADJ
brj-23874	227	4	inflammatory	inflammatory	ADJ
brj-23874	227	5	and	and	CCONJ
brj-23874	227	6	modulatory	modulatory	ADJ
brj-23874	227	7	effects	effect	NOUN
brj-23874	227	8	of	of	ADP
brj-23874	227	9	steroidal	steroidal	NOUN
brj-23874	227	10	saponins	saponin	NOUN
brj-23874	227	11	and	and	CCONJ
brj-23874	227	12	sapogenins	sapogenin	NOUN
brj-23874	227	13	on	on	ADP
brj-23874	227	14	cytokines	cytokine	NOUN
brj-23874	227	15	,	,	PUNCT
brj-23874	227	16	a	a	DET
brj-23874	227	17	review	review	NOUN
brj-23874	227	18	of	of	ADP
brj-23874	227	19	pre	pre	ADJ
brj-23874	227	20	-	-	ADJ
brj-23874	227	21	clinical	clinical	ADJ
brj-23874	227	22	research	research	NOUN
brj-23874	227	23	,	,	PUNCT
brj-23874	227	24	”	"	PUNCT
brj-23874	227	25	phytomedicine	phytomedicine	NOUN
brj-23874	227	26	(	(	PUNCT
brj-23874	227	27	96	96	NUM
brj-23874	227	28	)	)	PUNCT
brj-23874	227	29	,	,	PUNCT
brj-23874	227	30	article	article	NOUN
brj-23874	227	31	153842	153842	NUM
brj-23874	227	32	.	.	PUNCT
brj-23874	228	1	doi	doi	NOUN
brj-23874	228	2	:	:	PUNCT
brj-23874	228	3	10.1016	10.1016	NUM
brj-23874	228	4	/	/	SYM
brj-23874	228	5	j.phymed.2021.153842	j.phymed.2021.153842	PROPN
brj-23874	228	6	rao	rao	PROPN
brj-23874	228	7	,	,	PUNCT
brj-23874	228	8	v.	v.	ADV
brj-23874	228	9	,	,	PUNCT
brj-23874	228	10	and	and	CCONJ
brj-23874	228	11	poonia	poonia	PROPN
brj-23874	228	12	,	,	PUNCT
brj-23874	228	13	a.	a.	NOUN
brj-23874	228	14	(	(	PUNCT
brj-23874	228	15	2023	2023	NUM
brj-23874	228	16	)	)	PUNCT
brj-23874	228	17	.	.	PUNCT
brj-23874	229	1	“	"	PUNCT
brj-23874	229	2	citrullus	citrullus	VERB
brj-23874	229	3	colocynthis	colocynthis	NOUN
brj-23874	229	4	(	(	PUNCT
brj-23874	229	5	bitter	bitter	ADJ
brj-23874	229	6	apple	apple	NOUN
brj-23874	229	7	):	):	PUNCT
brj-23874	229	8	bioactive	bioactive	PROPN
brj-23874	229	9	compounds	compound	NOUN
brj-23874	229	10	,	,	PUNCT
brj-23874	229	11	nutritional	nutritional	ADJ
brj-23874	229	12	profile	profile	NOUN
brj-23874	229	13	,	,	PUNCT
brj-23874	229	14	nutraceutical	nutraceutical	ADJ
brj-23874	229	15	properties	property	NOUN
brj-23874	229	16	and	and	CCONJ
brj-23874	229	17	potential	potential	ADJ
brj-23874	229	18	food	food	NOUN
brj-23874	229	19	applications	application	NOUN
brj-23874	229	20	:	:	PUNCT
brj-23874	229	21	a	a	DET
brj-23874	229	22	review	review	NOUN
brj-23874	229	23	,	,	PUNCT
brj-23874	229	24	”	"	PUNCT
brj-23874	229	25	food	food	NOUN
brj-23874	229	26	prod	prod	NOUN
brj-23874	229	27	process	process	NOUN
brj-23874	229	28	and	and	CCONJ
brj-23874	229	29	nutr	nutr	NOUN
brj-23874	229	30	.	.	PROPN
brj-23874	229	31	5	5	NUM
brj-23874	229	32	,	,	PUNCT
brj-23874	229	33	4	4	NUM
brj-23874	229	34	.	.	X
brj-23874	229	35	doi	doi	NOUN
brj-23874	229	36	:	:	PUNCT
brj-23874	229	37	10.1186	10.1186	NUM
brj-23874	229	38	/	/	SYM
brj-23874	229	39	s43014022	s43014022	NOUN
brj-23874	229	40	-	-	PUNCT
brj-23874	229	41	00118	00118	NUM
brj-23874	229	42	-	-	SYM
brj-23874	229	43	9	9	NUM
brj-23874	229	44	rosa	rosa	PROPN
brj-23874	229	45	,	,	PUNCT
brj-23874	229	46	a.	a.	NOUN
brj-23874	229	47	,	,	PUNCT
brj-23874	229	48	rescigno	rescigno	NOUN
brj-23874	229	49	,	,	PUNCT
brj-23874	229	50	a.	a.	NOUN
brj-23874	229	51	,	,	PUNCT
brj-23874	229	52	piras	piras	NOUN
brj-23874	229	53	,	,	PUNCT
brj-23874	229	54	a.	a.	NOUN
brj-23874	229	55	,	,	PUNCT
brj-23874	229	56	atzeri	atzeri	PROPN
brj-23874	229	57	,	,	PUNCT
brj-23874	229	58	a.	a.	NOUN
brj-23874	229	59	,	,	PUNCT
brj-23874	229	60	scano	scano	PROPN
brj-23874	229	61	,	,	PUNCT
brj-23874	229	62	p.	p.	NOUN
brj-23874	229	63	,	,	PUNCT
brj-23874	229	64	porcedda	porcedda	PROPN
brj-23874	229	65	,	,	PUNCT
brj-23874	229	66	s.	s.	PROPN
brj-23874	229	67	,	,	PUNCT
brj-23874	229	68	zucca	zucca	NOUN
brj-23874	229	69	,	,	PUNCT
brj-23874	229	70	p.	p.	NOUN
brj-23874	229	71	,	,	PUNCT
brj-23874	229	72	and	and	CCONJ
brj-23874	229	73	assunta	assunta	VERB
brj-23874	229	74	dessì	dessì	PROPN
brj-23874	229	75	,	,	PUNCT
brj-23874	229	76	m.	m.	NOUN
brj-23874	229	77	(	(	PUNCT
brj-23874	229	78	2012	2012	NUM
brj-23874	229	79	)	)	PUNCT
brj-23874	229	80	.	.	PUNCT
brj-23874	230	1	“	"	PUNCT
brj-23874	230	2	chemical	chemical	ADJ
brj-23874	230	3	composition	composition	NOUN
brj-23874	230	4	and	and	CCONJ
brj-23874	230	5	effect	effect	NOUN
brj-23874	230	6	on	on	ADP
brj-23874	230	7	intestinal	intestinal	ADJ
brj-23874	230	8	caco-2	caco-2	NUM
brj-23874	230	9	cell	cell	NOUN
brj-23874	230	10	viability	viability	NOUN
brj-23874	230	11	and	and	CCONJ
brj-23874	230	12	lipid	lipid	NOUN
brj-23874	230	13	profile	profile	NOUN
brj-23874	230	14	of	of	ADP
brj-23874	230	15	fixed	fix	VERB
brj-23874	230	16	oil	oil	NOUN
brj-23874	230	17	from	from	ADP
brj-23874	230	18	cynomorium	cynomorium	PROPN
brj-23874	230	19	coccineum	coccineum	PROPN
brj-23874	230	20	l.	l.	PROPN
brj-23874	230	21	,	,	PUNCT
brj-23874	230	22	”	"	PUNCT
brj-23874	230	23	food	food	NOUN
brj-23874	230	24	chem	chem	NOUN
brj-23874	230	25	.	.	PUNCT
brj-23874	231	1	toxicol	toxicol	X
brj-23874	231	2	.	.	PUNCT
brj-23874	232	1	50(10	50(10	NUM
brj-23874	232	2	)	)	PUNCT
brj-23874	232	3	,	,	PUNCT
brj-23874	232	4	3799	3799	NUM
brj-23874	232	5	-	-	SYM
brj-23874	232	6	3807	3807	NUM
brj-23874	232	7	.	.	PUNCT
brj-23874	233	1	doi	doi	NOUN
brj-23874	233	2	:	:	PUNCT
brj-23874	233	3	10.1016	10.1016	NUM
brj-23874	233	4	/	/	SYM
brj-23874	233	5	j.fct.2012.07.003	j.fct.2012.07.003	PROPN
brj-23874	233	6	sakurai	sakurai	PROPN
brj-23874	233	7	,	,	PUNCT
brj-23874	233	8	y.	y.	PROPN
brj-23874	233	9	(	(	PUNCT
brj-23874	233	10	2015	2015	NUM
brj-23874	233	11	)	)	PUNCT
brj-23874	233	12	.	.	PUNCT
brj-23874	234	1	“	"	PUNCT
brj-23874	234	2	early	early	ADJ
brj-23874	234	3	-	-	PUNCT
brj-23874	234	4	stage	stage	NOUN
brj-23874	234	5	juvenile	juvenile	ADJ
brj-23874	234	6	fibromyalgia	fibromyalgia	NOUN
brj-23874	234	7	in	in	ADP
brj-23874	234	8	a	a	DET
brj-23874	234	9	12	12	NUM
brj-23874	234	10	-	-	PUNCT
brj-23874	234	11	year	year	NOUN
brj-23874	234	12	-	-	PUNCT
brj-23874	234	13	old	old	ADJ
brj-23874	234	14	girl	girl	NOUN
brj-23874	234	15	,	,	PUNCT
brj-23874	234	16	”	"	PUNCT
brj-23874	234	17	open	open	ADJ
brj-23874	234	18	journal	journal	NOUN
brj-23874	234	19	of	of	ADP
brj-23874	234	20	pediatrics	pediatric	NOUN
brj-23874	234	21	5(4	5(4	NUM
brj-23874	234	22	)	)	PUNCT
brj-23874	234	23	.	.	PUNCT
brj-23874	235	1	doi	doi	NOUN
brj-23874	235	2	:	:	PUNCT
brj-23874	235	3	10.4236	10.4236	NUM
brj-23874	235	4	/	/	SYM
brj-23874	235	5	ojped.2015.54053	ojped.2015.54053	ADJ
brj-23874	235	6	soyocak	soyocak	NOUN
brj-23874	235	7	,	,	PUNCT
brj-23874	235	8	a.	a.	NOUN
brj-23874	235	9	,	,	PUNCT
brj-23874	235	10	kurt	kurt	PROPN
brj-23874	235	11	,	,	PUNCT
brj-23874	235	12	h.	h.	PROPN
brj-23874	235	13	,	,	PUNCT
brj-23874	235	14	cosan	cosan	PROPN
brj-23874	235	15	,	,	PUNCT
brj-23874	235	16	d.	d.	PROPN
brj-23874	235	17	t.	t.	PROPN
brj-23874	235	18	,	,	PUNCT
brj-23874	235	19	saydam	saydam	NOUN
brj-23874	235	20	,	,	PUNCT
brj-23874	235	21	f.	f.	PROPN
brj-23874	235	22	,	,	PUNCT
brj-23874	235	23	calis	calis	PROPN
brj-23874	235	24	,	,	PUNCT
brj-23874	235	25	i.	i.	PROPN
brj-23874	235	26	u.	u.	PROPN
brj-23874	235	27	,	,	PUNCT
brj-23874	235	28	kolac	kolac	PROPN
brj-23874	235	29	,	,	PUNCT
brj-23874	235	30	uk	uk	PROPN
brj-23874	235	31	.	.	PROPN
brj-23874	235	32	,	,	PUNCT
brj-23874	235	33	koroglu	koroglu	PROPN
brj-23874	235	34	,	,	PUNCT
brj-23874	235	35	zo	zo	PROPN
brj-23874	235	36	.	.	PROPN
brj-23874	235	37	,	,	PUNCT
brj-23874	235	38	degirmenci	degirmenci	PROPN
brj-23874	235	39	,	,	PUNCT
brj-23874	235	40	i.	i.	PROPN
brj-23874	235	41	,	,	PUNCT
brj-23874	235	42	sahin	sahin	PROPN
brj-23874	235	43	mutlu	mutlu	PROPN
brj-23874	235	44	,	,	PUNCT
brj-23874	235	45	f.	f.	PROPN
brj-23874	235	46	,	,	PUNCT
brj-23874	235	47	and	and	CCONJ
brj-23874	235	48	gunes	gune	NOUN
brj-23874	235	49	,	,	PUNCT
brj-23874	235	50	h.	h.	PROPN
brj-23874	235	51	v.	v.	PROPN
brj-23874	235	52	(	(	PUNCT
brj-23874	235	53	2019	2019	NUM
brj-23874	235	54	)	)	PUNCT
brj-23874	235	55	.	.	PUNCT
brj-23874	236	1	“	"	PUNCT
brj-23874	236	2	tannic	tannic	ADJ
brj-23874	236	3	acid	acid	NOUN
brj-23874	236	4	exhibits	exhibit	VERB
brj-23874	236	5	antiinflammatory	antiinflammatory	NOUN
brj-23874	236	6	effects	effect	NOUN
brj-23874	236	7	on	on	ADP
brj-23874	236	8	formalin	formalin	NOUN
brj-23874	236	9	-	-	PUNCT
brj-23874	236	10	induced	induce	VERB
brj-23874	236	11	paw	paw	NOUN
brj-23874	236	12	edema	edema	NOUN
brj-23874	236	13	model	model	NOUN
brj-23874	236	14	of	of	ADP
brj-23874	236	15	inflammation	inflammation	NOUN
brj-23874	236	16	in	in	ADP
brj-23874	236	17	rats	rat	NOUN
brj-23874	236	18	,	,	PUNCT
brj-23874	236	19	”	"	PUNCT
brj-23874	236	20	hum	hum	NOUN
brj-23874	236	21	.	.	PUNCT
brj-23874	237	1	exp	exp	PROPN
brj-23874	237	2	.	.	PUNCT
brj-23874	238	1	toxicol	toxicol	PROPN
brj-23874	238	2	.	.	PUNCT
brj-23874	239	1	38	38	NUM
brj-23874	239	2	,	,	PUNCT
brj-23874	239	3	1296	1296	NUM
brj-23874	239	4	-	-	SYM
brj-23874	239	5	1301	1301	NUM
brj-23874	239	6	.	.	PUNCT
brj-23874	240	1	doi	doi	NOUN
brj-23874	240	2	:	:	PUNCT
brj-23874	240	3	10.1177/0960327119864154	10.1177/0960327119864154	NUM
brj-23874	240	4	schofield	schofield	PROPN
brj-23874	240	5	,	,	PUNCT
brj-23874	240	6	p.	p.	PROPN
brj-23874	240	7	,	,	PUNCT
brj-23874	240	8	dunham	dunham	PROPN
brj-23874	240	9	,	,	PUNCT
brj-23874	240	10	m.	m.	NOUN
brj-23874	240	11	,	,	PUNCT
brj-23874	240	12	martin	martin	PROPN
brj-23874	240	13	,	,	PUNCT
brj-23874	240	14	d.	d.	PROPN
brj-23874	240	15	,	,	PUNCT
brj-23874	240	16	bellamy	bellamy	PROPN
brj-23874	240	17	,	,	PUNCT
brj-23874	240	18	g.	g.	PROPN
brj-23874	240	19	,	,	PUNCT
brj-23874	240	20	francis	francis	PROPN
brj-23874	240	21	,	,	PUNCT
brj-23874	240	22	s.	s.	PROPN
brj-23874	240	23	a.	a.	PROPN
brj-23874	240	24	,	,	PUNCT
brj-23874	240	25	sookhoo	sookhoo	PROPN
brj-23874	240	26	,	,	PUNCT
brj-23874	240	27	d.	d.	PROPN
brj-23874	240	28	,	,	PUNCT
brj-23874	240	29	bonacaro	bonacaro	NOUN
brj-23874	240	30	,	,	PUNCT
brj-23874	240	31	a.	a.	PROPN
brj-23874	240	32	,	,	PUNCT
brj-23874	240	33	hamid	hamid	PROPN
brj-23874	240	34	,	,	PUNCT
brj-23874	240	35	e.	e.	PROPN
brj-23874	240	36	,	,	PUNCT
brj-23874	240	37	chandler	chandler	PROPN
brj-23874	240	38	,	,	PUNCT
brj-23874	240	39	r.	r.	PROPN
brj-23874	240	40	,	,	PUNCT
brj-23874	240	41	abdulla	abdulla	PROPN
brj-23874	240	42	,	,	PUNCT
brj-23874	240	43	a.	a.	PROPN
brj-23874	240	44	,	,	PUNCT
brj-23874	240	45	cumberbatch	cumberbatch	PROPN
brj-23874	240	46	,	,	PUNCT
brj-23874	240	47	m.	m.	NOUN
brj-23874	240	48	,	,	PUNCT
brj-23874	240	49	&	&	CCONJ
brj-23874	240	50	knaggs	knaggs	PROPN
brj-23874	240	51	,	,	PUNCT
brj-23874	240	52	r.	r.	PROPN
brj-23874	240	53	(	(	PUNCT
brj-23874	240	54	2022	2022	NUM
brj-23874	240	55	)	)	PUNCT
brj-23874	240	56	.	.	PUNCT
brj-23874	241	1	evidence	evidence	NOUN
brj-23874	241	2	-	-	PUNCT
brj-23874	241	3	based	base	VERB
brj-23874	241	4	clinical	clinical	ADJ
brj-23874	241	5	practice	practice	NOUN
brj-23874	241	6	guidelines	guideline	NOUN
brj-23874	241	7	on	on	ADP
brj-23874	241	8	the	the	DET
brj-23874	241	9	management	management	NOUN
brj-23874	241	10	of	of	ADP
brj-23874	241	11	pain	pain	NOUN
brj-23874	241	12	in	in	ADP
brj-23874	241	13	older	old	ADJ
brj-23874	241	14	people	people	NOUN
brj-23874	241	15	a	a	DET
brj-23874	241	16	summary	summary	NOUN
brj-23874	241	17	report	report	NOUN
brj-23874	241	18	.	.	PUNCT
brj-23874	242	1	british	british	ADJ
brj-23874	242	2	journal	journal	PROPN
brj-23874	242	3	of	of	ADP
brj-23874	242	4	pain	pain	NOUN
brj-23874	242	5	,	,	PUNCT
brj-23874	242	6	16(1	16(1	NUM
brj-23874	242	7	)	)	PUNCT
brj-23874	242	8	,	,	PUNCT
brj-23874	242	9	6–13	6–13	NOUN
brj-23874	242	10	.	.	PUNCT
brj-23874	243	1	doi	doi	NOUN
brj-23874	243	2	:	:	PUNCT
brj-23874	243	3	10.1177/2049463720976155	10.1177/2049463720976155	NUM
brj-23874	243	4	peer	peer	NOUN
brj-23874	243	5	-	-	PUNCT
brj-23874	243	6	reviewed	review	VERB
brj-23874	243	7	article	article	NOUN
brj-23874	243	8	bioresources.cnr.ncsu.edu	bioresources.cnr.ncsu.edu	VERB
brj-23874	243	9	zhu	zhu	PROPN
brj-23874	243	10	et	et	PROPN
brj-23874	243	11	al	al	PROPN
brj-23874	243	12	.	.	PROPN
brj-23874	244	1	(	(	PUNCT
brj-23874	244	2	2026	2026	NUM
brj-23874	244	3	)	)	PUNCT
brj-23874	244	4	.	.	PUNCT
brj-23874	245	1	“	"	PUNCT
brj-23874	245	2	pain	pain	NOUN
brj-23874	245	3	control	control	NOUN
brj-23874	245	4	with	with	ADP
brj-23874	245	5	seed	seed	NOUN
brj-23874	245	6	extract	extract	NOUN
brj-23874	245	7	,	,	PUNCT
brj-23874	245	8	”	"	PUNCT
brj-23874	245	9	bioresources	bioresource	NOUN
brj-23874	245	10	21(1	21(1	NUM
brj-23874	245	11	)	)	PUNCT
brj-23874	245	12	,	,	PUNCT
brj-23874	245	13	116	116	NUM
brj-23874	245	14	-	-	SYM
brj-23874	245	15	127	127	NUM
brj-23874	245	16	.	.	PUNCT
brj-23874	246	1	127	127	NUM
brj-23874	246	2	shah	shah	NOUN
brj-23874	246	3	,	,	PUNCT
brj-23874	246	4	m.	m.	NOUN
brj-23874	246	5	,	,	PUNCT
brj-23874	246	6	jan	jan	PROPN
brj-23874	246	7	,	,	PUNCT
brj-23874	246	8	h.	h.	PROPN
brj-23874	246	9	,	,	PUNCT
brj-23874	246	10	drouet	drouet	PROPN
brj-23874	246	11	,	,	PUNCT
brj-23874	246	12	s.	s.	PROPN
brj-23874	246	13	,	,	PUNCT
brj-23874	246	14	tungmunnithum	tungmunnithum	PROPN
brj-23874	246	15	,	,	PUNCT
brj-23874	246	16	d.	d.	PROPN
brj-23874	246	17	,	,	PUNCT
brj-23874	246	18	shirazi	shirazi	PROPN
brj-23874	246	19	,	,	PUNCT
brj-23874	246	20	j.	j.	PROPN
brj-23874	246	21	h.	h.	PROPN
brj-23874	246	22	,	,	PUNCT
brj-23874	246	23	hano	hano	PROPN
brj-23874	246	24	,	,	PUNCT
brj-23874	246	25	c.	c.	PROPN
brj-23874	246	26	,	,	PUNCT
brj-23874	246	27	and	and	CCONJ
brj-23874	246	28	abbasi	abbasi	PROPN
brj-23874	246	29	,	,	PUNCT
brj-23874	246	30	b.	b.	PROPN
brj-23874	246	31	h.	h.	PROPN
brj-23874	246	32	(	(	PUNCT
brj-23874	246	33	2021	2021	NUM
brj-23874	246	34	)	)	PUNCT
brj-23874	246	35	.	.	PUNCT
brj-23874	247	1	“	"	PUNCT
brj-23874	247	2	chitosan	chitosan	ADJ
brj-23874	247	3	elicitation	elicitation	NOUN
brj-23874	247	4	impacts	impact	VERB
brj-23874	247	5	flavonolignan	flavonolignan	NOUN
brj-23874	247	6	biosynthesis	biosynthesis	NOUN
brj-23874	247	7	in	in	ADP
brj-23874	247	8	silybum	silybum	NOUN
brj-23874	247	9	marianum	marianum	NOUN
brj-23874	247	10	(	(	PUNCT
brj-23874	247	11	l.	l.	PROPN
brj-23874	247	12	)	)	PUNCT
brj-23874	247	13	gaertn	gaertn	PROPN
brj-23874	247	14	cell	cell	NOUN
brj-23874	247	15	suspension	suspension	NOUN
brj-23874	247	16	and	and	CCONJ
brj-23874	247	17	enhances	enhance	VERB
brj-23874	247	18	antioxidant	antioxidant	ADJ
brj-23874	247	19	and	and	CCONJ
brj-23874	247	20	antiinflammatory	antiinflammatory	NOUN
brj-23874	247	21	activities	activity	NOUN
brj-23874	247	22	of	of	ADP
brj-23874	247	23	cell	cell	NOUN
brj-23874	247	24	extracts	extract	NOUN
brj-23874	247	25	,	,	PUNCT
brj-23874	247	26	”	"	PUNCT
brj-23874	247	27	molecules	molecule	NOUN
brj-23874	247	28	26(4	26(4	NUM
brj-23874	247	29	)	)	PUNCT
brj-23874	247	30	,	,	PUNCT
brj-23874	247	31	article	article	NOUN
brj-23874	247	32	791	791	NUM
brj-23874	247	33	.	.	PUNCT
brj-23874	248	1	doi	doi	NOUN
brj-23874	248	2	:	:	PUNCT
brj-23874	248	3	10.3390	10.3390	NUM
brj-23874	248	4	/	/	SYM
brj-23874	248	5	molecules26040791	molecules26040791	PROPN
brj-23874	248	6	zhang	zhang	PROPN
brj-23874	248	7	,	,	PUNCT
brj-23874	248	8	y.	y.	PROPN
brj-23874	248	9	h.	h.	PROPN
brj-23874	248	10	,	,	PUNCT
brj-23874	248	11	adamo	adamo	PROPN
brj-23874	248	12	,	,	PUNCT
brj-23874	248	13	d.	d.	PROPN
brj-23874	248	14	,	,	PUNCT
brj-23874	248	15	liu	liu	PROPN
brj-23874	248	16	,	,	PUNCT
brj-23874	248	17	h.	h.	PROPN
brj-23874	248	18	,	,	PUNCT
brj-23874	248	19	wang	wang	PROPN
brj-23874	248	20	,	,	PUNCT
brj-23874	248	21	q.	q.	PROPN
brj-23874	248	22	,	,	PUNCT
brj-23874	248	23	wu	wu	PROPN
brj-23874	248	24	,	,	PUNCT
brj-23874	248	25	w.	w.	PROPN
brj-23874	248	26	,	,	PUNCT
brj-23874	248	27	zheng	zheng	PROPN
brj-23874	248	28	,	,	PUNCT
brj-23874	248	29	y.	y.	PROPN
brj-23874	248	30	l.	l.	PROPN
brj-23874	248	31	,	,	PUNCT
brj-23874	248	32	and	and	CCONJ
brj-23874	248	33	wang	wang	PROPN
brj-23874	248	34	,	,	PUNCT
brj-23874	248	35	x.	x.	PROPN
brj-23874	248	36	q.	q.	PROPN
brj-23874	248	37	(	(	PUNCT
brj-23874	248	38	2023	2023	NUM
brj-23874	248	39	)	)	PUNCT
brj-23874	248	40	.	.	PUNCT
brj-23874	249	1	“	"	PUNCT
brj-23874	249	2	inflammatory	inflammatory	ADJ
brj-23874	249	3	pain	pain	NOUN
brj-23874	249	4	:	:	PUNCT
brj-23874	249	5	mechanisms	mechanism	NOUN
brj-23874	249	6	,	,	PUNCT
brj-23874	249	7	assessment	assessment	NOUN
brj-23874	249	8	,	,	PUNCT
brj-23874	249	9	and	and	CCONJ
brj-23874	249	10	intervention	intervention	NOUN
brj-23874	249	11	,	,	PUNCT
brj-23874	249	12	”	"	PUNCT
brj-23874	249	13	frontiers	frontier	NOUN
brj-23874	249	14	in	in	ADP
brj-23874	249	15	molecular	molecular	ADJ
brj-23874	249	16	neuroscience	neuroscience	NOUN
brj-23874	249	17	16	16	NUM
brj-23874	249	18	,	,	PUNCT
brj-23874	249	19	article	article	NOUN
brj-23874	249	20	1286215	1286215	NUM
brj-23874	249	21	.	.	PUNCT
brj-23874	250	1	doi	doi	NOUN
brj-23874	250	2	:	:	PUNCT
brj-23874	250	3	10.3389	10.3389	NUM
brj-23874	250	4	/	/	SYM
brj-23874	250	5	fnmol.2023.1286215	fnmol.2023.1286215	ADJ
brj-23874	250	6	article	article	NOUN
brj-23874	250	7	submitted	submit	VERB
brj-23874	250	8	:	:	PUNCT
brj-23874	250	9	august	august	PROPN
brj-23874	250	10	6	6	NUM
brj-23874	250	11	,	,	PUNCT
brj-23874	250	12	2024	2024	NUM
brj-23874	250	13	;	;	PUNCT
brj-23874	250	14	peer	peer	NOUN
brj-23874	250	15	review	review	NOUN
brj-23874	250	16	completed	complete	VERB
brj-23874	250	17	:	:	PUNCT
brj-23874	250	18	december	december	PROPN
brj-23874	250	19	23	23	NUM
brj-23874	250	20	,	,	PUNCT
brj-23874	250	21	2024	2024	NUM
brj-23874	250	22	;	;	PUNCT
brj-23874	250	23	revised	revise	VERB
brj-23874	250	24	version	version	NOUN
brj-23874	250	25	received	receive	VERB
brj-23874	250	26	and	and	CCONJ
brj-23874	250	27	accepted	accept	VERB
brj-23874	250	28	:	:	PUNCT
brj-23874	250	29	october	october	PROPN
brj-23874	250	30	24	24	NUM
brj-23874	250	31	,	,	PUNCT
brj-23874	250	32	2025	2025	NUM
brj-23874	250	33	;	;	PUNCT
brj-23874	250	34	published	publish	VERB
brj-23874	250	35	:	:	PUNCT
brj-23874	250	36	november	november	PROPN
brj-23874	250	37	10	10	NUM
brj-23874	250	38	,	,	PUNCT
brj-23874	250	39	2025	2025	NUM
brj-23874	250	40	.	.	PUNCT
brj-23874	251	1	doi	doi	NOUN
brj-23874	251	2	:	:	PUNCT
brj-23874	251	3	10.15376	10.15376	NUM
brj-23874	251	4	/	/	SYM
brj-23874	251	5	biores.21.1.116	biores.21.1.116	NOUN
brj-23874	251	6	-	-	SYM
brj-23874	251	7	127	127	NUM