Bibliography
This is an automatically generated bibliography describing the content of this study carrel.
- cord-000001-ug7v899j
- author: Madani, Tariq A
- title: Clinical features of culture-proven Mycoplasma pneumoniae infections at King Abdulaziz University Hospital, Jeddah, Saudi Arabia
- date: 2001-07-04
- words: 2459
- flesch: 35
- summary: It is hoped this information will assist clinicians in their approach and management of respiratory tract infections. A review of 101 hospitalized adult patients Respiration Atypical bacteria are a common cause of community-acquired pneumonia in hospitalized adults S Mycoplasma pneumoniae pneumonia requiring hospitalization, with emphasis on infection in the elderly Arch Intern Med Foy HM: Infections caused by Mycoplasma pneumoniae and possible carrier state in different populations of patients Role of Mycoplasma pneumoniae in acute respiratory-tract infections in Saudi paediatric patients The spectrum of pneumonia in 1983 at the Riyadh Armed Forces Community acquired acute bacterial and atypical pneumonia in Saudi Arabia Thorax Long-term epidemiology of infections with Mycoplasma pneumoniae Mycoplasma pneumoniae and adenovirus respiratory illness in military and university personnel Pneumonia caused by Mycoplasma pneumoniae infection The clinical spectrum and diagnosis of Mycoplasma pneumoniae infection Anemia and Mucocutaneous lesions due to Mycoplasma pneumoniae infections Clin Infect Dis Pericarditis and perimyocarditis associated with active Mycoplasma pneumoniae infection Mycoplasma pericarditis: evidence of invasive disease Clin Infect Dis CNS manifestations associated with Mycoplasma pneumoniae infections.
- keywords: acute; adults; age; arabia; bronchiolitis; cases; children; clinical; common; community; comorbidities; complications; culture; data; disease; hospital; immunocompromised; infections; isolates; mycoplasma; organism; patients; period; pneumoniae; recovery; respiratory; saudi; specimens; study; syndrome; system; tract; uneventful; university; upper; years
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- cord-000268-480d3yfv
- author: Porfyridis, Ilias
- title: Diagnostic value of triggering receptor expressed on myeloid cells-1 and C-reactive protein for patients with lung infiltrates: an observational study
- date: 2010-09-29
- words: 4277
- flesch: 39
- summary: Imaging of pneumonia: trends and algorithms Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia TREM-1(triggering receptor expressed on myeloid cells): a new player in acute inflammatory responses TREM-1 amplifies inflammation and is a crucial mediator of septic shock Does soluble triggering receptor expressed on myeloid cells-1 play any role in the pathogenesis of septic shock? Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumonia Serum of patients with septic shock stimulates the expression of Trem-1 on U937 monocytes Clinical review: Role of triggering receptor expressed on myeloid cells-1 during sepsis Triggering receptor expressed on myeloid cells-1 (TREM-1) is regulated post-transcriptionally and its ligand is present in the sera of some septic patients Soluble triggering receptor expressed on myeloid cells-1: a biomarker for bacterial meningitis Increased levels of soluble triggering receptor expressed on myeloid cells-1 in patients with acute pancreatitis Triggering receptor expressed on myeloid cells-1 expression on monocytes is associated with inflammation but not with infection in acute pancreatitis Soluble triggering receptor expressed on myeloid cells-1(sTREM-1): a new mediator involved in the pathogenesis of peptic ulcer disease Role of soluble triggering receptor expressed on myeloid cells-1 in inflammatory bowel disease TREM-1 expression in tumor-associated macrophages and clinical outcome in lung cancer Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by Marburg and ebola viruses Soluble triggering receptor expressed on myeloid cells 1 is released in patients with stable chronic obstructive pulmonary disease Increased plasma levels of soluble triggering receptor expressed on myeloid cells 1 and procalcitonin after cardiac surgery and cardiac arrest without infection The increased expression of TREM-1 on monocytes is associated with infectious and non-infectious inflammatory processes Soluble TREM-1 is not suitable for distinguishing between systemic inflammatory response syndrome and sepsis survivors and nonsurvivors in the early stage of acute inflammation Prognosis of community acquired pneumonia(CAP): value of triggering receptor expressed on myeloid cells-1 (TREM-1) and other mediators of the inflammatory response Timecourse of sTREM (soluble triggering receptor expressed on myeloid cells)-1, procalcitonin, and C-reactive protein plasma concentrations during sepsis Diagnosing pneumonia during mechanical ventilation: the clinical pulmonary infection score revisited Infectious Diseases Society of America Guidelines for the management of adult lower respiratory track infections Acute pulmonary embolism focused update incorporated into the ACC/AHA 2005 guidelines for the diagnosis and management of chronic heart failure in adults: A Report of the American College of Cardiology Foundation European Respiratory Society international multidisciplinary consensus classification of idiopathic interstitial pneumonias Early changes of CD4-positive lymphocytes and NK cells in patients with severe Gram-negative sepsis The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network: Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome TREM and TREM-like receptors in inflammation and disease The TREM receptor family and signal integration Monocytes as a site of production of soluble triggering receptor expressed on myeloid cells -1(sTREM-1) in the septic host Soluble triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis Soluble triggering receptor expressed on myeloid cells-1 as an antiinflammatory mediator in sepsis Soluble triggering receptor expressed on myeloid cells -1 key: cord-000268-480d3yfv authors: Porfyridis, Ilias; Plachouras, Diamantis; Karagianni, Vasiliki; Kotanidou, Anastasia; Papiris, Spyridon A; Giamarellou, Helen; Giamarellos-Bourboulis, Evangelos J title: Diagnostic value of triggering receptor expressed on myeloid cells-1 and C-reactive protein for patients with lung infiltrates: an observational study date: 2010-09-29 journal: BMC Infect Dis DOI: 10.1186/1471-2334-10-286 sha: doc_id: 268 cord_uid: 480d3yfv BACKGROUND: Differential diagnosis of patients with lung infiltrates remains a challenge.
- keywords: acute; admission; bacterial; blood; cap; cells; cells-1; chest; clinical; community; comparisons; concentrations; crp; data; day; diagnostic; disease; effusion; expression; failure; gram; greater; group; heart; icu; infectious; infiltrate; inflammatory; levels; lung; mfi; monocytes; myeloid; neutrophils; new; non; origin; patients; pleural; pneumonia; positive; pulmonary; receptor; respiratory; results; role; scores; sensitivity; sepsis; septic; serum; severe; soluble; specificity; strem-1; studies; study; syndrome
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- cord-000280-zyaj90nh
- author: Wong, Samuel YS
- title: Willingness to accept H1N1 pandemic influenza vaccine: A cross-sectional study of Hong Kong community nurses
- date: 2010-10-29
- words: 3487
- flesch: 41
- summary: World Health Organization Correlation between healthcare workers' knowledge of influenza vaccine and vaccine receipt Factors influencing update of influenza vaccination among hospital-based healthcare workers Nurses' contacts and potential for infectious disease transmission Influenza immunization: improving compliance of healthcare workers Uptake of influenza vaccine by healthcare workers in an acute hospital in Ireland Low acceptance of vaccination against the 2009 pandemic influenza A(H1N1) among healthcare workers in Greece Behviours regarding preventive measures against pandemic H1N1 influenza among Italian healthcare workers Willingness of Hong Kong healthcare workers to accept pre-pandemic influenza vaccination at different WHO alert levels: two questionnaire surveys Positive attitudes of French general practitioners towards A/ H1N1 influenza-pandemic vaccination: A missed opportunity to increase vaccination uptake in the general public? It is therefore not surprising that a recent online poll conducted in the UK suggested that nurses may be unwilling to receive pandemic influenza vaccination [15] .
- keywords: acceptability; acceptance; available; centres; cns; community; general; group; h1n1; healthcare; hong; hospital; infection; influenza; influenza vaccination; kong; low; months; nurses; nursing; pandemic; patients; previous; public; questionnaires; rate; respondents; response; results; risk; seasonal; service; studies; study; vaccination; vaccine; willingness; workers
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- cord-000332-u3f89kvg
- author: Broeck, Wouter Van den
- title: The GLEaMviz computational tool, a publicly available software to explore realistic epidemic spreading scenarios at the global scale
- date: 2011-02-02
- words: 7460
- flesch: 38
- summary: The 2009 H1N1 influenza pandemic highlighted the importance of computational epidemic models for the real-time analysis of the health emergency related to the global spreading of new emerging infectious diseases [1] [2] [3] . The GLEaMviz proxy middleware is the server component that mediates between clients and simulation engines.
- keywords: air; antiviral; application; approach; available; case; client; compartmental; components; computational; conditions; configuration; control; countries; data; day; definition; design; different; disease; drugs; dynamics; engine; epidemic; evolution; example; execution; figure; file; flexibility; gleamviz; gleamviz client; gleamviz simulation; gleamviz tool; global; h1n1; health; high; human; individuals; infectious; influenza; influenza pandemic; initial; interface; intervention; layer; level; like; map; middleware; mobility; model; modeling; multi; new; number; order; outbreak; pandemic; parameters; population; possible; proxy; range; realistic; results; run; scale; scenario; server; set; simulation; simulation engine; single; software; spread; spreading; stochastic; strategies; subpopulations; system; time; tool; travel; treatment; user; visualization; world
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- cord-000349-k0p166fr
- author: Olive, David
- title: Severe pneumococcal pneumonia: impact of new quinolones on prognosis
- date: 2011-03-15
- words: 3647
- flesch: 37
- summary: This combination, proposed by current guidelines as empirical treatment of severe CAP patients admitted in ICU could improve their prognosis. A review of its antibacterial activity, pharmacokinetics and therapeutic efficacy In-vitro activity of levofloxacin against Streptococcus pneumoniae with various levels of penicillin resistance A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia A multicenter, open-label, randomized comparison of levofloxacin vs azithromycin plus ceftriaxone in hospitalized adults with moderate to severe communityacquired pneumonia Multicenter, open-label, randomized study to compare the safety and efficacy of levofloxacin versus ceftriaxone sodium and erythromycin followed by clarithromycin and amoxicillin-clavulanate in the treatment of serious communityacquired pneumonia in adults Caulin E, for the levofloxacin study group: Comparison of levofloxacin and cefotaxime combined with ofloxacin for ICU patients with community-acquired pneumonia who do not require vasopressors Cefotaxime acts synergistically with levofloxacin in experimental meningitis due to penicillin resistant pneumococci and prevents selection of levofloxacin-resistant mutants in vitro In vitro interaction between ofloxacin and cefotaxime against grampositive and gram negative bacteria involved in serious infections Monotherapy may be suboptimal for severe bacteremic pneumococcal pneumonia International Pneumococcal Study Group: Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia The Acute Respiratory Distress Syndrome Network:
- keywords: acute; admission; analysis; antibiotic; cap; care; cephalosporin; ciprofloxacin; clinical; combination; community; data; empirical; failure; fluoroquinolone; generation; group; guidelines; hydrocortisone; icu; intensive; lactam; levofloxacin; lower; management; manuscript; mortality; new; organ; patients; pneumococcal; pneumonia; prognosis; respiratory; results; score; sepsis; severe; shock; significant; stay; study; survival; therapy; treatment; use; variables
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- cord-000441-5rm1za8z
- author: Curtale, Filippo
- title: Description of two measles outbreaks in the Lazio Region, Italy (2006-2007). Importance of pockets of low vaccine coverage in sustaining the infection
- date: 2010-03-11
- words: 4381
- flesch: 46
- summary: To assess presence of indigenous transmission or sources of imported virus the data set was integrated with information provided by the National Institute of Health (Istituto Superiore di Sanità, ISS), which conducted viral molecular characterization from urine samples of measles cases, utilising the PCR technique [12] . When analysed separately, the age distribution of measles cases was different among the Roma/Sinti population (median age two years) with respect to the rest of the population (median age 15 years).
- keywords: aged; analysis; asp; august; authorities; cases; children; communities; confirmed; contacts; coverage; data; dose; elimination; epidemiological; ethnic; europe; figure; genotype; health; hospital; incidence; infection; italian; italy; june; laboratory; lazio; local; low; measles; mmr; molecular; national; nosocomial; outbreak; population; region; rest; roma; rome; school; second; serotype; sinti; spread; surveillance; susceptible; symptoms; transmission; vaccination; vaccine; virus; years
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- cord-000451-te75jsd3
- author: Liu, Qiyong
- title: Forecasting incidence of hemorrhagic fever with renal syndrome in China using ARIMA model
- date: 2011-08-15
- words: 2825
- flesch: 44
- summary: Some previous studies [30, 31] in China also used ARIMA model to fit and forecast HFRS incidence of some regions, but they had the same problem that the number of observations was not enough, which led to the instability of their forecast results. Therefore, there is an urgent need for monitoring and predicting HFRS incidence to make the control of HFRS more effective.
- keywords: analysis; arima; arima model; autoregressive; average; box; cases; china; control; data; disease; fever; fit; forecasting; health; hemorrhagic; hemorrhagic fever; hfrs; hfrs incidence; incidence; infectious; level; mean; model; modeling; monitoring; moving; number; order; prediction; prevention; renal; renal syndrome; results; seasonal; series; statistical; study; surveillance; syndrome; time; values; years
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- cord-000457-e50a0suk
- author: Rhim, Jung-Woo
- title: Epidemiological and clinical characteristics of childhood pandemic 2009 H1N1 virus infection: an observational cohort study
- date: 2011-08-24
- words: 3749
- flesch: 43
- summary: Because this pandemic occurred over 40 years after last pandemic (Hong Kong flu), there have been no controlled-clinical trials for the efficacy of corticosteroids on influenza virus infections, although yearly seasonal influenza and small cases of sporadic H5N1 avian influenza virus infection have occurred during inter-pandemic period. Although influenza virus infection has been a major global concern since the pandemic 1918 'Spanish flu', there have been no pandemic influenzas for near four decades after the 1968 'Hong Kong flu'.
- keywords: acute; admission; age; cases; characteristics; chest; children; clinical; corticosteroids; day; doses; early; factors; fever; figure; group; h1n1; higher; hospital; hospitalization; illness; immune; infection; influenza; injury; korea; lobar; lower; lung; lymphocyte; lymphopenia; male; oseltamivir; pandemic; patients; period; pneumonia; radiographic; rate; respiratory; segmental; severe; severity; studies; study; treatment; viral; virus; years
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- cord-000534-ztc5holk
- author: Hsieh, Ying-Hen
- title: Transmissibility and temporal changes of 2009 pH1N1 pandemic during summer and fall/winter waves
- date: 2011-12-02
- words: 5206
- flesch: 47
- summary: Figure 2 Model fit for the 2-wave Richards model using weekly confirmed pH1N1 case data by sample receiving week in Taiwan. The weekly laboratory confirmed pH1N1 case data (by the week when the samples were collected and sent to the TCDC-contracted laboratories) and the weekly hospitalization data (by the week the lab-confirmed cases were hospitalized) from June 28, 2009 (epidemiological week or e-week 27 of 2009) to March 27, 2010 (e-week 12 of 2010) was accessed from the weekly Influenza Express made publicly available on the internet by the TCDC [22] during the epidemic.
- keywords: case; central; class; confirmed; cumulative; curve; daily; data; days; disease; early; epidemic; estimates; fall; figure; hospitalization; immunization; infections; influenza; july; lower; mass; mexico; model; november; number; outbreak; pandemic; ph1n1; point; policy; reproduction; results; richards; richards model; school; second; second wave; september; study; summer; suspension; taiwan; temporal; time; transmissibility; turning; use; virus; wave; week; weekly; winter
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- cord-000562-ocp6yodg
- author: Swaan, Corien M
- title: Timeliness of contact tracing among flight passengers for influenza A/H1N1 2009
- date: 2011-12-28
- words: 4020
- flesch: 47
- summary: In this study we evaluated the timeliness of contact tracing (CT) of flight contacts in daily practice. The main reason for flight contact tracing is raising alertness for possible exposure to uncommon infectious diseases, enabling early recognition and treatment of the disease and timely installation of control measures (e.g. SARS and viral hemorrhagic fevers).
- keywords: airline; airport; arrival; available; case; cib; close; contact; control; data; date; days; delay; details; diagnosis; disease; dutch; exposure; flight; h1n1; health; index; infectious; influenza; interval; investigations; laboratory; lists; medical; netherlands; pandemic; passenger; patients; pep; period; phase; plc; requests; study; symptoms; time; timeliness; transmission
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- cord-000619-3bakci02
- author: Zhang, Peng-jun
- title: Clinical features and risk factors for severe and critical pregnant women with 2009 pandemic H1N1 influenza infection in China
- date: 2012-02-01
- words: 3112
- flesch: 50
- summary: Evidence on the useful role of NIV in pregnant patients with ARDS secondary H1N1 viral infection was lacking. key: cord-000619-3bakci02 authors: Zhang, Peng-jun; Li, Xiao-li; Cao, Bin; Yang, Shi-gui; Liang, Li-rong; Gu, Li; Xu, Zhen; Hu, Ke; Zhang, Hong-yuan; Yan, Xi-xin; Huang, Wen-bao; Chen, Wei; Zhang, Jing-xiao; Li, Lan-juan; Wang, Chen title: Clinical features and risk factors for severe and critical pregnant women with 2009 pandemic H1N1 influenza infection in China date: 2012-02-01 journal: BMC Infect Dis DOI: 10.1186/1471-2334-12-29 sha: doc_id: 619 cord_uid: 3bakci02 BACKGROUND: 2009 pandemic H1N1 (pH1N1) influenza posed an increased risk of severe illness among pregnant women.
- keywords: admission; analysis; bmi; cases; china; chinese; clinical; critical; data; death; delivery; factors; h1n1; higher; hospital; illness; infection; influenza; information; invasive; iqr; maternal; mortality; neonatal; niv; outcomes; pandemic; pao; patients; pregnancy; pregnant; premature; rate; reported; respiratory; risk; severe; study; table; trimester; ventilation; virus; women
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- cord-000963-pwz6rde0
- author: Kalugalage, Thilini
- title: Low serum total nitrite and nitrate levels in severe leptospirosis
- date: 2013-05-06
- words: 4068
- flesch: 51
- summary: On the other hand, no difference was seen in corrected NO x levels in severe leptospirosis patients, healthy controls and NLF patients. NO x levels in leptospirosis patients with mild and severe disease, healthy controls and non-leptospirosis fever patients (NLFs), and c) seek a correlation between serum
- keywords: activity; acute; blood; clinical; colombo; confirmed; controls; creatinine; difference; disease; dysfunction; elevated; equivocal; fever; griess; groups; healthy; high; higher; impairment; infections; inos; lanka; leptospirosis; levels; low; lower; malaria; marker; mat; mild; nhsl; nitric; nitrite; no(x; non; organ; oxide; patients; presence; relationship; renal; serum; severe; severity; similar; sri; study; table; total; x levels
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- cord-000996-ef5d81cg
- author: Han, Seung Beom
- title: Clinical characteristics and antimicrobial susceptibilities of viridans streptococcal bacteremia during febrile neutropenia in patients with hematologic malignancies: a comparison between adults and children
- date: 2013-06-17
- words: 4624
- flesch: 31
- summary: Pediatr Blood Cancer Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients Antimicrobial susceptibility of viridans group streptococci isolated from patients with acute leukemia receiving ofloxacin for antibacterial prophylaxis Emergence of quinolone resistance among viridans group streptococci isolated from the oropharynx of neutropenic peripheral blood stem cell transplant patients receiving quinolone antimicrobial prophylaxis Penicillin-resistant viridans streptococci have obtained altered penicillinbinding protein genes from penicillin-resistant strains of Streptococcus pneumoniae Erythromycin and penicillin resistance mechanisms among viridans group streptococci isolated from blood cultures of adult patients with underlying diseases Trimethoprimsulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease ANSORP Study Group: The lower susceptibility rate of 66.1% to cefepime in children may indicate the need for initial glycopeptide therapy in febrile neutropenic children.
- keywords: adults; analysis; antibacterial; antibiotic; attributable; bacteremia; blood; cancer; cases; cefepime; characteristics; chemotherapy; children; clinical; complications; crp; days; death; diagnosis; different; episodes; febrile; group; hematologic; iqr; isolates; laboratory; lower; malignancies; median; neutropenic; occurrence; oral; patients; peak; penicillin; previous; prophylaxis; rate; resistance; severe; severe complications; significant; streptococci; study; susceptibility; susceptible; therapy; viridans; vsb
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- cord-001050-lq9tp20z
- author: Khanafer, Nagham
- title: Severe leukopenia in Staphylococcus aureus-necrotizing, community-acquired pneumonia: risk factors and impact on survival
- date: 2013-08-01
- words: 3463
- flesch: 36
- summary: Death occurred in 75.8% of severe leukopenia cases with median survival time of 4 days, and in 16.3% of cases with leukocyte count >3,000/mL (P<0.001). Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients Life-threatening hemoptysis in adults with community-acquired pneumonia due to Panton-Valentine leukocidinsecreting Staphylococcus aureus Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season Severe community-acquired pneumonia caused by Panton-Valentine leukocidin-positive Staphylococcus aureus: first reported case in the United Kingdom Destructive pulmonary embolism in a patient with community-acquired staphylococcal bacteremia Comparison of community-and health care-associated methicillinresistant Staphylococcus aureus infection Epidemiology and outcomes of community-associated methicillinresistant Staphylococcus aureus infection Pulmonary manifestations in children with invasive community-acquired Staphylococcus aureus infection Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureus reference strain Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus Severe sepsis and septic shock in the emergency department Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing Panton-Valentine leukocidin Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils Diagnosis of a predisposition of retinoblastoma at the DNA level Community-associated methicillinresistant Staphylococcus aureus in outpatients Age-related changes in human hematopoietic stem/progenitor cells HTLV
- keywords: admission; age; airway; analysis; association; aureus; bleeding; cases; clinical; community; count; data; disease; factors; female; furuncles; gender; group; history; hospital; hospitalization; human; infection; leukocidin; leukocytes; leukopenia; median; mortality; multivariate; necrotizing; p<0.001; panton; patients; personal; pneumonia; pvl; rate; regression; risk; severe; severe leukopenia; severity; staphylococcus; study; survival; symptoms; valentine; variables; years
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- cord-001470-hn288o97
- author: Pivette, Mathilde
- title: Drug sales data analysis for outbreak detection of infectious diseases: a systematic literature review
- date: 2014-11-18
- words: 4424
- flesch: 48
- summary: Most studies compared drug sales data to reference surveillance data using correlation measurements or indicators of outbreak detection performance (sensitivity, specificity, timeliness of the detection). Nineteen studies retrospectively compared drug sales data to reference clinical data, and significant correlations were observed in 17 of them.
- keywords: analysis; articles; authors; available; clinical; correlation; counter; data; department; detection; disease; drug; drug sales; early; emergency; example; gastrointestinal; groups; health; illness; incidence; increase; infectious; influenza; literature; method; new; otc; outbreak; patients; performance; pharmacies; population; products; public; real; reference; respiratory; results; retrospective; review; sales; search; selection; sensitivity; signal; significant; sources; specificity; studies; study; surveillance; syndromic; system; systematic; terms; time; timeliness; warning
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- cord-001512-u3u2k8hj
- author: Ding, Hua
- title: A family cluster of three confirmed cases infected with avian influenza A (H7N9) virus in Zhejiang Province of China
- date: 2014-12-31
- words: 5094
- flesch: 49
- summary: Data collection for H7N9 cases was determined by the National for H7N9 cases was determined y f man of China, as a part of the continuing public health outbreak investigation; therefore, it was exempt from assessment by institutional review board. Based on the Chinese guidance, an individual could be considered as a confirmed case of H7N9 virus infection if the presence of the H7N9 virus is verified by real-time reverse transcriptase polymerase chain reaction assay (RT-PCR), virus isolation, or serologic testing [19] . Epidemiological and clinical data were collected through interviews and reviews of medical records between January 13 and 25, 2014.
- keywords: acid; amino; analyses; avian; avian influenza; bird; blood; care; case; cdc; china; clinical; close; cluster; confirmed; contacts; daily; data; days; environmental; exposure; family; figure; h5n1; h7n9; h7n9 virus; hospital; hours; human; illness; index; index case; infected; infection; influenza; isolates; january; live; market; negative; novel; onset; pcr; person; positive; poultry; province; respiratory; samples; secondary; serum; sputum; strains; surveillance; symptoms; table; throat; transmission; virus; zhejiang
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- cord-001725-pw7coi3v
- author: Ballus, Josep
- title: Surgical site infection in critically ill patients with secondary and tertiary peritonitis: epidemiology, microbiology and influence in outcomes
- date: 2015-07-30
- words: 3443
- flesch: 40
- summary: The epidemiology of intra-abdominal flora in critically ill patients with secondary and tertiary abdominal sepsis Intensive care unit management of intra-abdominal infection Risk factors for severe sepsis in secondary peritonitis Surgical infections in the critically ill Risk factors for wound infection after surgery for colorectal cancer CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections Surgical wound infection: epidemiology, pathogenesis, diagnosis and Management APACHE II: a severity of disease classification system Implications of 2,457 consecutive surgical infections entering year 2000 Adverse impact of surgical site infections in English hospitals National nosocomial infections surveillance system (NNIS): description of surveillance methods Microbiological diagnosis of intra-abdominal infections Overview of the etiology of wound infections with particular emphasis on community-acquired illnesses A risk factor analysis of healthcare-associated fungal infections in an intensive care unit: a retrospective cohort study Fungal infections in ICU patients: epidemiology and the role of diagnostics Continuous, 10-year wound infection surveillance: results, advantages, and unanswered questions The authors wish to thank the ICU nurses and all members of the general surgery department for their contribution to the study and for their care of the patients reported in this paper. However, we concede that TPN is a risk factor for all types of fungal infection in ICU, especially among surgical patients [20] .
- keywords: abdominal; acute; admission; analysis; antibiotic; care; clinical; cultures; data; diagnosis; epidemiology; factors; following; higher; hospital; icu; ill; incidence; infection; intra; mean; microbiological; microbiology; microorganisms; mortality; nosocomial; outcomes; patients; peritonitis; physiology; population; rates; research; resistant; results; risk; score; secondary; severity; site; spp; ssi; ssis; stay; study; surgery; surgical; tertiary; tissue; treatment; type; wound
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- cord-001746-pbahviaz
- author: Garg, Shikha
- title: Pneumonia among adults hospitalized with laboratory-confirmed seasonal influenza virus infection—United States, 2005–2008
- date: 2015-08-26
- words: 4421
- flesch: 27
- summary: The etiology of influenza-associated pneumonia may include primary influenza pneumonia, secondary bacterial pneumonia, or Pulmonary complications of influenza Rates of pneumonia during influenza epidemics in Seattle Influenza pneumonia: a descriptive study Pulmonary complications of interpandemic influenza A in hospitalized adults Adult hospitalizations for laboratory-positive influenza during the Influenzaassociated pneumonia in children hospitalized with laboratory-confirmed influenza Viral pneumonia in older adults Immunology of the aging lung Physiological changes in respiratory function associated with ageing Risk factors for pneumonia and other lower respiratory tract infections in elderly residents of long-term care facilities Lessons from a nursing home outbreak of influenza A Prevention and control of seasonal influenza with vaccines: recommendations of the advisory committee on immunization practices-United States Children with asthma hospitalized with seasonal or pandemic influenza Bacterial pneumonia during the Hong Kong influenza epidemic of 1968-1969 Influenza-associated pediatric mortality in the United States: increase of Staphylococcus aureus coinfection Influenza-associated mortality among children -United States Staphylococcus aureus pneumonia in children in the era of community-acquired methicillin-resistance at Texas Children's Hospital Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season Infectious diseases society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children Updated recommendations for prevention of invasive pneumococcal disease among adults using the 23-valent pneumococcal polysaccharide vaccine (PPSV23) Clinical characteristics and outcomes of H1N1-associated pneumonia among adults in South Korea Factors associated with death in hospitalized pneumonia patients with 2009 H1N1 influenza in Shenyang, China Pneumonia and respiratory failure from swineorigin influenza A (H1N1) in Mexico Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California Oseltamivir and risk of lower respiratory tract complications in patients with flu symptoms: a meta-analysis of eleven randomized clinical trials Benefit of early treatment with oseltamivir in hospitalized patients with documented 2009 influenza A (H1N1): retrospective cohort study Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations Antiviral agents for the treatment and chemoprophylaxis of influenza -recommendations of the Advisory Committee on Immunization Practices (ACIP) Van Hal SJ.
- keywords: acquisition; admission; adults; age; analysis; antiviral; aor; asthma; aureus; bacterial; chronic; complications; conception; conditions; critical; cxr; data; days; death; design; diagnosis; discharge; disease; factors; hospital; icd-9; icu; infection; influenza; interpretation; laboratory; likely; manuscript; medical; nursing; older; pandemic; patients; pneumonia; pulmonary; respiratory; results; review; seasonal; severe; sterile; study; surveillance; table; treatment; underlying; virus; years
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- cord-001922-zfpg6dgj
- author: Zhang, Xu-Sheng
- title: Construction of the influenza A virus transmission tree in a college-based population: co-transmission and interactions between influenza A viruses
- date: 2016-01-29
- words: 4596
- flesch: 46
- summary: However, the concluded enhancement of A/H3N2 virus infectivity within Predicting pneumonia and influenza mortality from morbidity data Global patterns in seasonal activity of influenza A/H3N2, A/H1N1, and B from 1997 to 2005: viral coexistence and latitudinal gradients Rapid differentiation of mixed influenza A/H1N1 virus infections with seasonal and pandemic variants by multitemperature single-stranded conformational polymorphism analysis Evaluation of Alere I influenza A & B for rapid detection of influenza A and B Cross-subtype protection in humans during sequential, overlapping, and or concurrent epidemics caused by H3N2 and H1N1 influenza-viruses Mixed infection and the genesis of influenza virus diversity Fitness of pandemic H1N1 and seasonal influenza A viruses during co-infection Pandemic (H1N1) 2009 and seasonal influenza A(H1N1) co-infection Co-infection with pandemic H1N1 and seasonal H3N2 influenza viruses Dual infection of novel influenza viruses A/H1N1 and A/H3N2 in a cluster of Cambodian patients Isolation of influenza A/H3 and B viruses from an influenza patient: confirmation of co-infection by two influenza viruses Mixed infections of pandemic H1N1 and seasonal H3N2 viruses in 1 outbreak Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures Robust reconstruction and analysis of outbreak data: influenza A(H1N1)v transmission in a schoolbased population Transmission parameters of the A/ H1N1 (2009) influenza virus pandemic: a review A simplex method for function minimization Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature Bayesian Reconstruction of Disease Outbreaks by Combining Epidemiologic and Genomic Data Influenza and community-acquired pneumonia interactions: the impact of order and time of infection on population patterns The impact of coinfections and their simultaneous transmission on antigenic diversity and epidemic cycling of infectious diseases Strain interactions as a mechanism for dominant strain alternation and incidence oscillation in infectious diseases: seasonal influenza as a case study This research was funded by the Public Health England. Here g(Δt |θ) denotes the probability density of the generation interval distribution of influenza infection, with θ representing the set of parameters that characterise the probability density distribution.
- keywords: building; case; college; contact; data; different; distribution; dormitories; estimate; fig; generation; h1n1; h3n2; index; individuals; infected; infection; infectivity; influenza; information; interval; liu; method; number; outbreak; pandemic; patients; possible; reproductive; seasonal; symptom; transmissibility; transmission; tree; type; virus; viruses
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- cord-002828-ml6mgyf3
- author: Huang, Linna
- title: Application of extracorporeal membrane oxygenation in patients with severe acute respiratory distress syndrome induced by avian influenza A (H7N9) viral pneumonia: national data from the Chinese multicentre collaboration
- date: 2018-01-08
- words: 4904
- flesch: 46
- summary: (25 ± 5 cmH(2)O vs. 21 ± 3 cmH(2)O, P < 0.05) and VT (343 ± 96 ml vs. 246 ± 93 ml, P < 0.05) after 48 h on ECMO support. The former refers to a group of patients whose condition improved and were weaned from ECMO for at least 48 h; the unsuccessfully weaned group refers to those who died or voluntarily discontinued treatment due to lack of improvement during ECMO support.
- keywords: act; acute; additional; anticoagulation; ards; avian; avian influenza; blood; cases; china; complications; data; disease; distress; duration; ecmo; extracorporeal; failure; file; flow; group; h7n9; haemorrhage; high; higher; infection; influenza; ippv; lung; management; membrane; min; mmhg; mortality; national; oxygenation; parameters; patients; plat; pneumonia; pre; rate; respiratory; severe; strategies; study; support; syndrome; time; total; treatment; ventilation; virus
- versions: original; plain text
- cord-002853-vj8t28hn
- author: Joffe, Michael
- title: Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient
- date: 2018-01-27
- words: 2131
- flesch: 37
- summary: There are several well-known risk factors for severe adenovirus infections, including: allogeneic stem cell (or solid-organ) transplantation, particularly with T-cell depletion; treatment with anti-CD52 monoclonal antibody (alemtuzumab or Campath) or anti-thymocyte globulin (ATG); severe immunosuppression used to treat graft-versus-host disease; and any other cause of severe lymphopaenia that reduces the ability of the host's cell-mediated immunity to defend against adenovirus infection [1] . key: cord-002853-vj8t28hn authors: Joffe, Michael; Wagner, Simon D.; Tang, Julian W. title: Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient date: 2018-01-27 journal: BMC Infect Dis DOI: 10.1186/s12879-018-2962-7 sha: doc_id: 2853 cord_uid: vj8t28hn BACKGROUND:
- keywords: 9]/l; adenovirus; adult; authors; blood; case; cell; chemotherapy; chest; chronic; clinical; copies; dna; earlier; fatal; fludarabine; haematology; hepatitis; infection; lymphocytic; non; patient; pcr; peripheral; positive; report; respiratory; sample; severe; testing; transplant; treatment; viral; week
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- cord-003085-7krf1yxz
- author: Li, Xi
- title: Cytomegalovirus infection and outcome in immunocompetent patients in the intensive care unit: a systematic review and meta-analysis
- date: 2018-06-28
- words: 3797
- flesch: 37
- summary: However, whether CMV infection or CMV reactivation contributes to mortality of immunocompetent patients remains unclear. For CMV seropositive patients, the OR for mortality in patients with CMV reactivation as compared with patients without CMV reactivation was 1.72 (95%CI 1.04–2.85, I(2) = 29%, n = 664).
- keywords: 95%ci; additional; analysis; antiviral; blood; care; cause; clinical; cmv; cmv infection; critically; cytomegalovirus; data; days; detection; drugs; figure; file; higher; human; i(2; icu; ill; immune; immunocompetent; incidence; infection; intensive; manuscript; mechanical; median; meta; mortality; n =; organ; outcome; patients; pcr; rate; reactivation; results; sepsis; stay; studies; study; treatment; ventilation
- versions: original; plain text
- cord-003372-cpl7zf7f
- author: Provoost, Judith
- title: A retrospective study of factors associated with treatment decision for nontuberculous mycobacterial lung disease in adults without altered systemic immunity
- date: 2018-12-14
- words: 3389
- flesch: 34
- summary: In the absence of systemic immunodeficiency, decision of NTM lung disease treatment must relies on a careful risk/benefit assessment, given the requirement of long-term administration of multidrug therapies supported by limited evidence. This retrospective, single center study (2013–2016, 45 months) addressed the criteria supporting treatment decision among adults with NTM lung disease without systemic immunodeficiency at our institution, with the assigned goal to harmonize the practice.
- keywords: active; adults; analysis; anti; aspergillus; assessment; ats; bronchiectasis; chronic; clinical; criteria; culture; data; decision; diagnosis; disease; factors; final; group; guidelines; idsa; immunodeficiency; important; infection; initiation; lung; lyon; management; manuscript; months; mortality; mycobacterial; nontuberculous; ntm; ntm lung; ntm treatment; number; outcome; patients; positive; prior; pulmonary; radiological; retrospective; single; society; spp; study; systemic; treatment; untreated; variables; version
- versions: original; plain text
- cord-003397-fvrd128w
- author: Herath, H. M. L. Y.
- title: Spotted fever rickettsioses causing myocarditis and ARDS: a case from Sri Lanka
- date: 2018-12-29
- words: 2555
- flesch: 47
- summary: He was confirmed to have spotted fever rickettsial infection with rising titre of indirect immunofluorescence antibodies to Ricketssia conorii and made a complete recovery with appropriate antibiotic therapy and supportive care. This case demonstrates a rather rare presentation of spotted fever rickettsial infection where patient deteriorated within short time leading to shock and ARDS.
- keywords: acute; admission; ards; authors; available; blood; cardiac; care; cases; causing; central; chloramphenicol; complications; conorii; data; day; diagnosis; evidence; failure; fever; group; high; hospital; illness; infections; intravenous; lanka; management; manifestations; min; msf; myocarditis; normal; patient; presence; presentation; rare; rash; respiratory; rickettsial; rickettsioses; severe; skin; sri; tick; titre; treatment
- versions: original; plain text
- cord-003425-c5jdp5jv
- author: Fu, Yangxi
- title: Human adenovirus type 7 infection causes a more severe disease than type 3
- date: 2019-01-09
- words: 5666
- flesch: 40
- summary: Adenovirus: epidemiology, global spread of novel serotypes, and advances in treatment and prevention Pneumonia and massive pleural effusion associated with adenovirus type 7 Adenovirus pneumonia complicated with acute respiratory distress syndrome: a case report First report of sudden death due to myocarditis caused by adenovirus serotype 3 Adenovirus infection associated with central nervous system dysfunction in children Molecular epidemiology of adenovirus types 3 and 7 isolated from children with pneumonia in Beijing Lower respiratory tract infections due to adenovirus in hospitalized Korean children: epidemiology, clinical features, and prognosis Human adenoviruses in respiratory infections: sequencing of the hexon hypervariable region reveals high sequence variability Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy Identification and typing of respiratory adenoviruses in Guangzhou, southern China using a rapid and simple method A simple and efficient method for purification of infectious recombinant adenovirus A comparison of viral fitness and virulence between emergent adenovirus 14p1 and prototype adenovirus 14p strains In vitro characterization of human adenovirus type 55 in comparison with its parental adenoviruses, types 11 and 14 Pring-Akerblom P. Rapid and quantitative detection of human adenovirus DNA by real-time PCR Quantitative real-time PCR assay panel for detection and type-specific identification of epidemic respiratory human adenoviruses A novel factor I activity in Nipah virus inhibits human complement pathways through cleavage of C3b MMP-12-mediated by SARM-TRIF signaling pathway contributes to IFNgamma-independent airway inflammation and AHR post RSV infection in nude mice Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndromes Transient hemiparesis and hemianesthesia in an atypical case of adult-onset clinically mild encephalitis/ encephalopathy with a reversible splenial lesion associated with adenovirus infection The effect of hemoperfusion on patients with toxic encephalopathy induced by silkworm chrysalis ingestion The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system Cytokine induction by respiratory syncytial virus and adenovirus in bronchial epithelial cells Complement: a unique innate immune sensor for danger signals Complement. Severe adenovirus infection in children can be complicated with pleural effusions
- keywords: a549; activation; acute; adenovirus; adenovirus infection; airway; analysis; balf; blood; c3a; cells; children; china; clinical; complement; culture; cytokine; data; days; differences; different; disease; encephalopathy; failure; fig; fitness; group; hadv-7; hadv-7 infection; higher; hospital; human; il-1β; il-6; immune; infected; infection; inflammation; inflammatory; levels; lower; lung; macrophages; manuscript; medical; mice; moi; neutrophils; number; patients; pneumonia; positive; post; pulmonary; respiratory; response; results; samples; serotypes; severe; significant; specific; studies; study; system; time; total; toxic; tract; type; university; viral; viruses; vitro; vivo; vps
- versions: original; plain text
- cord-003460-legakasx
- author: Qiu, Junke
- title: APACHE-II score for anti-tuberculosis tolerance in critically ill patients: a retrospective study
- date: 2019-02-04
- words: 3682
- flesch: 38
- summary: Analysis of the treatment of pulmonary tuberculosis in elderly patients at a university hospital in Rio de Janeiro, Brazil Population aging and migrant workers: bottlenecks in tuberculosis control in rural China Adherence to anti-tuberculosis treatment and treatment outcomes among tuberculosis patients in Alamata District, Northeast Ethiopia Determinants of non adherence to tuberculosis treatment in Argentina: barriers related to access to treatment Tuberculosis treatment nonadherence and lost to follow up among TB patients with or without HIV in developing countries: a systematic review Factors influencing non-adherence to tuberculosis treatment in Jepara Adherence to treatment and supervision for tuberculosis in a DOTS programme among pastoralists in Uganda Factors associated with interruption of treatment among Pulmonary Tuberculosis patients in Plateau State Factors associated with adherence to treatment with isoniazid for the prevention of tuberculosis amongst people living with HIV/AIDS: a systematic review of qualitative data Factors associated with treatment adherence for tuberculosis infection Non-adherence to antituberculosis treatment and determinant factors among patients with tuberculosis in Northwest Ethiopia APACHE II: a severity of disease classification system Ministry of health clinical practice guidelines: prevention, diagnosis and Management of Tuberculosis Severity of illness and organ failure assessment in adult intensive care units Systematic review of anti-tuberculosis drug induced adverse reactions in China Adverse reactions to antituberculosis drugs in in-hospital patients: severity and risk factors Frequency of adverse reactions to first-and second-line anti-tuberculosis chemotherapy in a Korean cohort Antituberculosis drugs adverse reactions: a review of the Iranian literature Substantially higher and earlier occurrence of anti-tuberculosis drug-related adverse reactions in HIV Coinfected tuberculosis patients: a matched-cohort study Safety and tolerability profile of secondline anti-tuberculosis medications Adverse reactions of anti-tuberculosis drugs in hospitalized patients: incidence, severity and risk factors TB meets COPD: an emerging global co-morbidity in human lung disease Tuberculosis and chronic respiratory disease: a systematic review COPD and the risk of tuberculosis--a population-based cohort study Tuberculosisassociated mortality and its risk factors in a district of Shanghai, China: a retrospective cohort study Mortality and predictors in pulmonary tuberculosis with respiratory failure requiring mechanical ventilation Predictors of development and outcome in patients with acute respiratory distress syndrome due to tuberculosis A study of the prognostic factors associated with mortality in critically ill patients with tuberculous Contributing factors to mortality rates of pulmonary tuberculosis in intensive care units Profile of patients with active tuberculosis admitted to a respiratory intensive care unit in a tertiary Care Center of North India The prevalence and evolution of anemia associated with tuberculosis Effect of anti-tuberculosis drugs on hematological profiles of tuberculosis patients attending at University of Gondar Hospital Anemia at the initiation of tuberculosis therapy is associated with delayed sputum conversion among pulmonary tuberculosis patients in The causes of treatment cessation in the patients suffering from pulmonary tuberculosis An official ATS statement: hepatotoxicity of antituberculosis therapy Cutaneous adverse drug reactions caused by antituberculosis drugs A case of thrombocytopenia caused by rifampicin and pyrazinamide A case of pulmonary tuberculosis complicated with severe thrombocytopenia during treatment Drug-induced complications of anti-tuberculosis drugs in HIV patients Acute kidney injury due to anti-tuberculosis drugs: a five-year experience in an aging population The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. In particular, elderly patients with tuberculosis tend to have more extensive pulmonary lesions, higher sputum positivity, a higher susceptibility to the adverse effects of anti-tuberculosis drugs (including hepatic dysfunction) and higher mortality
- keywords: adherence; adverse; analysis; anti; apache; care; china; clinical; completion; copd; data; disease; drug; drug withdrawal; dysfunction; elderly; factors; failure; group; hemoglobin; higher; hospital; ill; incidence; independent; intensive; level; liver; lower; mortality; non; patients; points; pulmonary; rate; reactions; resistance; respiratory; risk; score; severity; study; table; therapy; treatment; tuberculosis; value; withdrawal
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- cord-003466-599x0euj
- author: Nickol, Michaela E.
- title: A year of terror and a century of reflection: perspectives on the great influenza pandemic of 1918–1919
- date: 2019-02-06
- words: 5774
- flesch: 42
- summary: The emergence of pandemic influenza viruses Summary report on the Asian influenza epidemic in Japan 1957 Public health and medical responses to the 1957-58 influenza pandemic Global mortality impact of the 1957-1959 influenza pandemic Estimated global mortality associated with the first 12 months of 2009 pandemic influenza a H1N1 virus circulation: a modelling study Antigenic similarity of influenza a (H1N1) viruses from epidemics in 1977--1978 to The 1918 influenza pandemic: lessons for 2009 and the future The Spanish flu--part II: the second and third wave Paths of infection: the first world war and the origins of the 1918 influenza pandemic The Spanish flu--part Analyses of influenza virus genome sequences also suggest that the initial entry of the 1918 precursor virus into human circulation began in 1915 and did not appear to have jumped directly from an avian source [4, 38, 39] .
- keywords: able; adults; age; antivirals; avian; bacterial; canada; cases; century; china; circulating; deaths; development; disease; early; emergence; estimated; europe; fatal; fatalities; fatality; final; future; global; h1n1; health; healthcare; high; history; hospitalizations; human; illness; individuals; infections; influenza; influenza pandemic; influenza virus; low; months; mortality; new; north; origin; pandemic; pandemic virus; possible; potential; prior; protection; public; rates; respiratory; seasonal; second; severe; similar; spanish; spread; states; strains; subtype; understanding; united; universal; vaccination; vaccine; viral; virus; viruses; war; wave; worldwide; years; young
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- cord-003526-ykisq8nz
- author: Kallel, Hatem
- title: Capillary leak-syndrome triggered by Maripa virus in French Guiana: case report and implication for pathogenesis
- date: 2019-03-15
- words: 1952
- flesch: 37
- summary: Hantavirus pulmonary syndrome Hantavirus pulmonary syndrome caused by Maripa virus in French Guiana Hantavirus pulmonary syndrome, French Guiana Maripa virus RNA load and antibody response in hantavirus pulmonary syndrome Immunopathogenesis of hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome: do CD8+ T cells trigger capillary leakage in viral hemorrhagic fevers? Cyclical edema and shock due to increased capillary permeability Capillary leakage in travelers with dengue infection : implications for pathogenesis Zika virus in the Americas: a review for clinicians Zika and chikungunya: emerging arboviruses in the New World Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant Severe Puumala virus infection in a patient with a lymphoproliferative disease treated with icatibant Endothelial cell permeability during hantavirus infection involves factor XIIdependent increased activation of the kallikrein-kinin system Thrombocytopenia associates with the severity of inflammation and variables reflecting capillary leakage in Puumala hantavirus infection, an analysis of 546 Finnish patients Mechanisms of shock in hantavirus pulmonary syndrome Written informed consent was obtained from the patient for publication of this Case Report and accompanying images. We conclude that HPS secondary to Maripa virus infection in French Guiana can cause severe damages leading to Multi Organ Failure.
- keywords: acute; admission; capillary; case; cell; day; disease; endothelial; failure; french; guiana; hantavirus; hemodynamic; hps; human; icu; increased; index; infection; inflammatory; leakage; level; low; maripa; mechanism; normal; patient; permeability; pleural; protein; pulmonary; renal; report; respiratory; severe; severity; shock; syndrome; vascular
- versions: original; plain text
- cord-003533-8m0vyxq8
- author: Jayathilaka, P. G. N. S.
- title: An outbreak of leptospirosis with predominant cardiac involvement: a case series
- date: 2019-03-18
- words: 4150
- flesch: 47
- summary: key: cord-003533-8m0vyxq8 authors: Jayathilaka, P. G. N. S.; Mendis, A. S. V.; Perera, M. H. M. T. S.; Damsiri, H. M. T.; Gunaratne, A. V. C.; Agampodi, Suneth Buddhika title: An outbreak of leptospirosis with predominant cardiac involvement: a case series date: 2019-03-18 journal: BMC Infect Dis DOI: 10.1186/s12879-019-3905-7 sha: doc_id: 3533 cord_uid: 8m0vyxq8 BACKGROUND: Severe leptospirosis is known to cause multi organ dysfunction including cardiac involvement. We present a case series of severe leptospirosis with cardiac involvement observed during a period of one month at Colombo-North Teaching Hospital, Sri Lanka.
- keywords: abdomen; acute; admission; blood; cardiac; case; changes; clinical; count; creatinine; day; days; dengue; diagnosis; ecg; echocardiogram; evidence; fever; fluid; high; history; hospital; illness; infection; intravenous; involvement; lanka; leptospirosis; liver; mild; month; myocarditis; normal; number; output; patients; positive; possible; pressure; protein; reactive; recovery; renal; series; serum; severe; shock; sinus; sri; tachycardia; titre; troponin; urine
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- cord-003803-1t4xyayf
- author: He, Hangyong
- title: Successful management of refractory respiratory failure caused by avian influenza H7N9 and secondary organizing pneumonia: a case report and literature review
- date: 2019-07-29
- words: 2572
- flesch: 45
- summary: And a steroid dose of methylprednisolone 1.5 mg/kg may be suggested for treatment of OP associated with avian influenza H7N9 infection. In this report, we describe the first case of OP associated with avian influenza H7N9 infection.
- keywords: analysis; avian; case; chest; clinical; condition; consolidation; daily; data; days; dose; ecmo; examination; failure; fever; findings; h1n1; h7n9; high; icu; improvement; infection; influenza; lung; methylprednisolone; organizing; patient; pneumonia; primary; refractory; respiratory; severe; steroid; virus; week
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- cord-003856-05u4t67u
- author: Mao, Ying
- title: A descriptive analysis of the Spatio-temporal distribution of intestinal infectious diseases in China
- date: 2019-09-02
- words: 5146
- flesch: 49
- summary: HFMD and OIDD exhibited high incidence rates, which reflected the negligence of Class C diseases by the government. Higher incidence rates for OIDD and Hepatitis A were observed in summer and autumn.
- keywords: additional; analysis; areas; autocorrelation; beijing; btt; cases; china; chinese; cholera; class; cluster; data; decomposition; different; diseases; distribution; dysentery; foot; global; hand; hepatitis; hfmd; high; iids; incidence; incidence rates; infectious; infectious diseases; intestinal; local; low; moran; mouth; number; observed; oidd; present; prevention; province; rates; regions; results; risk; scan; seasonal; secondary; space; spatial; spatio; study; summer; tap; temporal; time; trend; typhoid; units; variation; viral; west
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- cord-004110-xc8vv9x8
- author: Eslahi, Aida Vafae
- title: Prevalence of Toxocara and Toxascaris infection among human and animals in Iran with meta-analysis approach
- date: 2020-01-07
- words: 5142
- flesch: 36
- summary: Consequently, the production of specific antibodies provides the most complete evidence for Toxocara infection, which is the base of diagnostic tests such as ELISA and Western blot for reactivity to larval TES antigen in various carnivores and human populations in Iran; (D) Studies that detected Toxocara infection using at least one of the parasitological, serological and molecular methods; (e) exact total sample size, positive samples and the respective prevalence rates were available.
- keywords: additional; analysis; animal; areas; articles; authors; available; canis; carnivores; cases; cati; cats; country; current; data; detection; different; disease; dogs; domestic; eggs; felis; figure; file; foxes; health; helminth; high; higher; highest; hosts; human; human toxocara; infection; intestinal; investigations; involved; iran; jackal; larvae; latitude; leonina; meta; method; molecular; northern; parasites; parts; population; prevalence; public; rates; records; red; regions; review; risk; rural; seroprevalence; soil; species; spp; stray; studies; study; systematic; t. canis; t. cati; total; toxascaris; toxascaris infection; toxocara; toxocariasis; urban; vulpes; weighted; western; worldwide; zoonotic
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- cord-004198-h8ch3x14
- author: Ebuy, Hiluf
- title: HIV testing, test results and factors influencing among infants born to HIV positive mothers in public hospitals of Mekelle City, North Ethiopia: a cross-sectional study
- date: 2020-01-21
- words: 4506
- flesch: 52
- summary: key: cord-004198-h8ch3x14 authors: Ebuy, Hiluf; Bekele, Alemayehu; Redae, Getachew title: HIV testing, test results and factors influencing among infants born to HIV positive mothers in public hospitals of Mekelle City, North Ethiopia: a cross-sectional study date: 2020-01-21 journal: BMC Infect Dis DOI: 10.1186/s12879-020-4790-9 sha: doc_id: 4198 cord_uid: h8ch3x14 BACKGROUND: Timely infant testing for HIV is critical to ensure optimal treatment outcomes among exposed infants. There were 291(52.2%) female HIV exposed infants (Table 1) PMTCT service and clinical characteristics among mothers The majority (95.0%) of the mothers had attended ANC and 529(94.8%) mothers were on ART on entry to the PMTCT cohort.
- keywords: 18th; adherence; aids; anc; antibody; aor; arv; association; birth; care; child; city; data; dna; ethiopia; factors; feeding; follow; general; health; higher; hiv; hiv positivity; hospital; infant testing; infants; mekelle; month; mothers; odds; options; overall; participants; pcr; pmtct; positive; positivity; prevention; program; prophylaxis; public; rural; status; study; testing; timely; timely infant; transmission; variables; years
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- cord-004239-cu6atqvr
- author: Morikane, Keita
- title: Clinical and microbiological effect of pulsed xenon ultraviolet disinfection to reduce multidrug-resistant organisms in the intensive care unit in a Japanese hospital: a before-after study
- date: 2020-01-29
- words: 3175
- flesch: 42
- summary: The role of environmental cleaning in the control of hospitalacquired infection Reduction of Clostridium difficile and vancomycin-resistant Enterococcus contamination of environmental surfaces after an intervention to improve cleaning methods Evaluation of a pulsed-xenon ultraviolet room disinfection device for impact on hospital operations and microbial reduction Is the pulsed xenon ultraviolet light no-touch disinfection system effective on methicillin-resistant Staphylococcus aureus in the absence of manual cleaning? Evaluation of a pulsed xenon ultraviolet light device for isolation room disinfection in a United Kingdom hospital Impact of a multi-hospital intervention utilizing screening, hand hygiene education and pulsed xenon ultraviolet (PX-UV) on the rate of hospital associated methicillin resistant Staphylococcus aureus infection Implementation and impact of ultraviolet environmental disinfection in an acute care setting Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the benefits of enhanced terminal room disinfection study): a cluster-randomised, multicentre, crossover study The effect of portable pulsed xenon ultraviolet light after terminal cleaning on hospital-associated Clostridium difficile infection in a community hospital Clostridium difficile infections before and during use of ultraviolet disinfection Utilization and impact of a pulsed-xenon ultraviolet room disinfection system and multidisciplinary care team on Clostridium difficile in a long-term acute care facility A trial of pulsed xenon ultraviolet disinfection to reduce Clostridioides difficile infection Ministry of Health Labour and Welfare of Japan website Environmental contamination due to methicillin-resistant Staphylococcus aureus; possible infection control implications Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations key: cord-004239-cu6atqvr authors: Morikane, Keita; Suzuki, Shoko; Yoshioka, Jun; Yakuwa, Jun; Nakane, Masaki; Nemoto, Kenji title: Clinical and microbiological effect of pulsed xenon ultraviolet disinfection to reduce multidrug-resistant organisms in the intensive care unit in a Japanese hospital: a before-after study date: 2020-01-29 journal: BMC Infect Dis DOI: 10.1186/s12879-020-4805-6 sha: doc_id: 4239 cord_uid: cu6atqvr BACKGROUND: No-touch environmental disinfection using ultraviolet devices has been highlighted in the past several years to control the transmission of multidrug-resistant organisms (MDROs).
- keywords: 2dra; acinetobacter; acquisition; cleaning; contamination; curtains; decrease; device; difficile; discharge; disinfection; effect; effectiveness; environmental; healthcare; hospital; icu; incidence; light; manual; microbiological; mrsa; new; pathogens; patient; period; portable; resistant; rooms; sampling; setting; significant; study; terminal; test; transmission; ultraviolet; xenon
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- cord-004316-mnqn1t3q
- author: Zhao, Xia
- title: Epidemiological and clinical characteristics of healthcare-associated infection in elderly patients in a large Chinese tertiary hospital: a 3-year surveillance study
- date: 2020-02-10
- words: 3190
- flesch: 39
- summary: World population prospects: the 2017 revision, key findings and advance tables Prevalence, incidence burden, and clinical impact of healthcare-associated infections and antimicrobial resistance: a national prevalent cohort study in acute care hospitals in Greece Effect of healthcare-acquired infection on length of hospital stay and cost Hospital-acquired infections in Belgian acute-care hospitals: an estimation of their global impact on mortality, length of stay and healthcare costs Cañon-Montañez W. Risk factors for health care-associated infection in hospitalized adults: systematic review and meta-analysis Are short-stay units an appropriate resource for hospitalising elderly patients with infection? Elderly patients are at high risk from hospital-acquired infection Bloodstream infections in older patients Risk factors of health care-associated infection in elderly patients: a retrospective cohort study performed at a tertiary Hospital in China Clinical relevance of age-related immune dysfunction The Ministry of Public Health. The five most common pathogens detected in elderly HAI patients were Candida albicans, Klebsiella pneumonia, Acinetobacter baumannii, Escherichia coli, and Pseudomonas aeruginosa.
- keywords: bloodstream; care; catheter; central; china; clabsi; clinical; comorbidities; control; data; days; density; disease; elderly; elderly patients; factors; group; hais; healthcare; higher; hospital; icu; incidence; infection; information; lower; medical; non; patients; rates; respiratory; risk; stay; study; surveillance; system; time; tract; urinary; use; vap; years
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- cord-004394-0h2wvv40
- author: Li, Fengqin
- title: Vancomycin-resistant Enterococcus faecium pneumonia in a uremic patient on hemodialysis: a case report and review of the literature
- date: 2020-02-22
- words: 2494
- flesch: 32
- summary: In conclusion, VRE pneumonia is rarely reported. Case report and review of the literature A case of pneumonia due to Enterococcus faecium after near drowing Strongyloides hyperinfection syndrome and VRE pneumonia Vancomycin-resistant Enterococcus faecium empyema in an Asplenic patient Enterococcal pneumonia.
- keywords: antibiotic; aspiration; blood; case; catheter; chest; clinical; culture; disease; drug; empyema; enterococcus; epilepsy; epileptic; exudation; faecium; failure; fever; fig; healthcare; hemodialysis; hospital; infections; linezolid; literature; lung; multiple; negative; nosocomial; patient; pneumonia; recurrent; report; resistant; respiratory; sputum; temperature; uremic; vancomycin; vre; week
- versions: original; plain text
- cord-004395-erqmbi2b
- author: Bugembe, Daniel Lule
- title: Computational MHC-I epitope predictor identifies 95% of experimentally mapped HIV-1 clade A and D epitopes in a Ugandan cohort
- date: 2020-02-22
- words: 4415
- flesch: 37
- summary: In this analysis we showed that the computational method NetMHCpan4.0 predicted 95% of previously experimentally mapped HIV-1 epitopes in 6 HIV-1 infected individuals expressing a total of 22 different HLA class I alleles. A community resource benchmarking predictions of peptide binding to MHC-I molecules Efficient peptide-MHC-I binding prediction for alleles with few known binders MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides Automated benchmarking of peptide-MHC class I binding predictions An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions Largescale validation of methods for cytotoxic T-lymphocyte epitope prediction Reliable prediction of T-cell epitopes using neural networks with novel sequence representations MHCflurry: open-source class I MHC binding affinity prediction T-cell antigenic sites tend to be amphipathic structures Emerging vaccine informatics Prediction of peptide-MHC binding using profiles Comparison of experimental fine-mapping to in silico prediction results of HIV-1 epitopes reveals ongoing need for mapping experiments Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection Macrophage inflammatory Protein-1
- keywords: 14mer; affinity; algorithm; alleles; analysis; assays; auc; binders; binding; cell; class; computational; curve; data; design; early; elispot; epitopes; experimental; false; fig; gag; hit; hiv-1; hla; individuals; infected; infection; late; length; mapping; mer; methods; mhcflurry1.2.0; multiple; netmhcpan4.0; number; participants; peptides; point; positives; predicted; predictions; responses; roc; score; sequences; set; single; specific; study; subtypes; table; test; time; true; uganda; vaccine; virus; wells; wet
- versions: original; plain text
- cord-004397-ypli7wtu
- author: Ma, Zhan-Ying
- title: Suspension microarray-based comparison of oropharyngeal swab and bronchoalveolar lavage fluid for pathogen identification in young children hospitalized with respiratory tract infection
- date: 2020-02-22
- words: 3230
- flesch: 39
- summary: BALF and OPS identified respiratory pathogen infections in 57 (75%) and 49 (64.5%) patients, respectively (P > 0.05). BALF and OPS identified respiratory pathogen infections in 57 (75%) and 49 (64.5%) cases, respectively ( Table 2 ).
- keywords: array; balf; cases; catarrhalis; children; china; clinical; comparison; detection; high; hospital; identification; illness; infections; lower; methods; microarray; microbiological; moraxella; nasopharyngeal; ops; oropharyngeal; pathogens; patients; pcr; pediatric; pneumonia; respiratory; results; rsv; rti; samples; sampling; sensitivity; specimens; study; suspension; swab; testing; time; tract; upper; virus; viruses; young
- versions: original; plain text
- cord-004471-1r714dmm
- author: Seo, Jun-Won
- title: Scalp eschar and neck lymphadenopathy after tick bite (SENLAT) caused by Bartonella henselae in Korea: a case report
- date: 2020-03-12
- words: 2530
- flesch: 56
- summary: And then, based on previous several literature showing that water deer living in Korea serve as a reservoirs of Bartonella species [16, 17] , we believed that B. henselae identified in our patient originated from a water deer contacted prior to our hospital visit. Vector Borne Zoonotic Dis Bartonella henselae as a cause of prolonged fever and fever of unknown origin in children Scalp eschar and neck lymphadenopathy after tick bite: an emerging syndrome with multiple causes Scalp eschar and neck lymphadenopathy caused by Bartonella henselae after tick bite Characterization of clinical isolates of Bartonella henselae strains Detection of bartonella henselae DNA by polymerase chain reaction in a patient with cat scratch disease: a case report Bartonella henselae infection presenting with a picture of adult-onset Still's disease Case report: Coinfection with rickettsia monacensis and Orientia tsutsugamushi Prevalence, isolation and molecular characterization of Bartonella species in Republic of Korea Detection of Bartonella species from ticks, mites and small mammals in Korea Prevalence of Bartonella henselae and Bartonella clarridgeiae in cats and dogs in Korea Microbial pathogens in ticks, rodents and a shrew in northern Gyeonggi-do near the DMZ Korea Molecular detection of Bartonella henselae DNA from fleas obtained from dogs Korea Tick-borne lymphadenopathy, an emerging disease Molecular detection of Bartonella grahamii and B. schoenbuchensis-related species in Korean water deer (Hydropotes inermis argyropus).
- keywords: area; bartonella; bite; blood; case; cat; cervical; confirmed; days; deer; detection; disease; enlarged; eschar; fever; fig; henselae; ifa; infection; korea; lymph; lymphadenopathy; neck; node; patient; pcr; positive; report; rickettsia; right; scalp; scratch; senlat; species; tibola; tick; vector; visit; water
- versions: original; plain text
- cord-004488-r50atew9
- author: Chong, Zhuo Lin
- title: Diagnostic accuracy and utility of three dengue diagnostic tests for the diagnosis of acute dengue infection in Malaysia
- date: 2020-03-12
- words: 7108
- flesch: 48
- summary: Declaration of Helsinki -Ethical Principles for Medical Research Involving Human Subjects Sample size estimation in diagnostic test studies of biomedical informatics Quantification of NS1 dengue biomarker in serum via optomagnetic nanocluster detection Bioline Dengue Duo product insert Evaluation of a commercial SD dengue virus NS1 antigen capture enzyme-linked immunosorbent assay kit for early diagnosis of dengue virus infection Comparison of capture immunoglobulin M (IgM) and IgG enzyme-linked immunosorbent assay (ELISA) and nonstructural protein NS1 serotypespecific IgG ELISA for differentiation of primary and secondary dengue virus infections World Health Organization. The addition of serology component to SD Bioline Dengue Duo, however, greatly enhanced its diagnostic accuracy and utility parameters almost beyond that of SD Dengue NS1 ELISA, making it a better point-of-care dengue diagnostic tool as it would miss the fewest dengue patients.
- keywords: 95%ci; accuracy; acute; analysis; antigen; assays; available; better; bioline; biosensors; blood; capillary; care; clinical; combination; combo; commercial; component; days; dengue; dengue ns1; denv-1; detection; diagnostic; difference; disease; duo; elisa; estimates; evaluated; evaluation; health; higher; igg; igm; index; individual; infection; laboratory; lower; malaysia; negative; ns1; ns1 rdt; parameters; patients; pcr; performance; point; positive; presumptive; primary; probability; rapid; rdt; reference; research; results; sample; sd bioline; sd ns1; secondary; sensitivity; serology; serum; significant; specificity; standard; studies; study; table; tests; utility; venous; virotrack; virus
- versions: original; plain text
- cord-004643-uu4uipfy
- author: Hasan, Mohammad Rubayet
- title: Unusual accumulation of a wide array of antimicrobial resistance mechanisms in a patient with cytomegalovirus-associated hemophagocytic lymphohistiocytosis: a case report
- date: 2020-03-20
- words: 3022
- flesch: 32
- summary: The case highlights both the risk of acquiring MDR superbugs and the severity of these infections in HLH patients. While these factors likely put HLH patients at high risk of infection with MDROs, no such reports has been published to date and the clinical course of such infections in these patients remains unknown.
- keywords: antibiotic; antimicrobial; antiviral; bacteria; bleeding; blood; case; clinical; cmv; coli; course; culture; cytomegalovirus; data; day; drug; fever; ganciclovir; genes; genetic; genome; hemophagocytic; high; history; hlh; hospital; india; infection; isolate; lymphohistiocytosis; manuscript; mdros; mechanisms; metagenomic; multidrug; multiple; pandrug; patient; picu; pid; pneumoniae; positive; resistance; respiratory; risk; sequence; sequencing; therapy; treatment; urine; vancomycin; vre; wgs
- versions: original; plain text
- cord-008584-4eylgtbc
- author: Singh, David E.
- title: Evaluating the impact of the weather conditions on the influenza propagation
- date: 2020-04-05
- words: 7281
- flesch: 42
- summary: Our meteorological model is based on the regression model developed by AB and JS, and it is tuned with influenza surveillance data obtained from SISSS. This component is tuned with influenza surveillance data obtained from SISSS to provide realistic simulations.
- keywords: absolute; authors; average; cases; changes; climate; community; conditions; contact; data; degrees; different; distribution; effect; epidemic; epigraph; et al; evolution; factors; figure; final; health; humidity; impact; individuals; infected; infection; influenza; influenza propagation; influenza surveillance; information; initial; input; like; meteorological; meteorological data; meteorological model; model; mortality; national; network; number; pandemic; paper; parameters; patterns; population; previous; propagation; rates; real; realistic; regions; related; relative; relative humidity; results; scenario; seasonal; sentinel; short; simulated; simulations; simulator; sisss; social; spain; spanish; study; surveillance; system; temperature; term; time; transmission; urban; vaccination; values; virus; weather; work
- versions: original; plain text
- cord-009210-qhul89z2
- author: Chen, Jie
- title: Diagnosis of severe scrub typhus infection by next-generation sequencing:a case report
- date: 2020-04-07
- words: 2326
- flesch: 46
- summary: = 317;61.20%), propionibacterium, staphylococcus, acinetobacter, sphingomonas, pseudomonas Endemic scrub typhus in South America Severe scrub typhus infection: Clinical features, diagnostic challenges and management A Concise Review of the Epidemiology and Diagnostics of Rickettsioses: Rickettsia and Orientia spp Optimal cutoff titers for indirect immunofluorescence assay for diagnosis of scrub typhus Use of eschar swabbing for the molecular diagnosis and genotyping of Orientia tsutsugamushi causing scrub typhus in Quang Nam province Laboratory-acquired scrub typhus and murine typhus infections: the argument for a risk-based approach to biosafety requirements for Orientia tsutsugamushi and rickettsia typhi laboratory activities Actionable diagnosis of neuroleptospirosis by next-generation sequencing Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip Affordable HIV drug-resistance testing for monitoring of antiretroviral therapy in sub-Saharan Africa Imported scrub typhus: first case in South America and review of the literature The clinical significance of upper gastrointestinal endoscopy in gastrointestinal vasculitis related to scrub typhus Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Scrub typhus is an acute febrile illness, which was caused by Orientia tsutsugamushi and transmitted through the bite of chiggers.
- keywords: 6th; acute; authors; blood; case; causative; culture; data; day; days; determined; diagnosis; doxycycline; eschar; fever; fig; generation; human; illness; infection; july; mods; multiple; ngs; organ; orientia; pancreatic; pathogen; patient; plasma; platelet; reads; renal; sample; scrub; scrub typhus; sequencing; severe; shock; specific; study; test; treatment; tsutsugamushi; typhus
- versions: original; plain text
- cord-009606-xz23twqx
- author: Vorobieva S. Jensen, V.
- title: Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines
- date: 2020-04-15
- words: 6175
- flesch: 39
- summary: Three other PCV-13associated serotypes 1, 5 and 7F are not frequently detected among pneumococcal carriage isolates in Russia The serotype distribution was diverse in the area, but globally reported epidemiological features, such as age-dependence, Carriage rates A 38.4% overall frequency of pneumococcal carriage rate was found in non-vaccinated pre-school children.
- keywords: 19a; analysis; antimicrobial; arkhangelsk; asymptomatic; authors; birth; carriage; cases; characterization; children; clonal; clones; collection; conjugate; consumption; countries; coverage; data; day; disease; distribution; epidemiology; european; expansion; factors; guardians; health; high; immunization; introduction; invasive; ipd; isolates; local; low; macrolide; mdr; molecular; months; multidrug; nasopharyngeal; national; non; number; overall; parents; pcv-13; pcvs; pen; penicillin; pneumococcal; pneumoniae; population; programme; rates; region; reported; resistance; risk; russia; samples; sampling; schedule; serotype; significant; strains; streptococcus; streptococcus pneumoniae; sts; study; surveillance; susceptibility; susceptible; table; vaccination; vaccine; valent; vvsj; years
- versions: original; plain text
- cord-011601-1u1rlwzp
- author: Biribawa, Claire
- title: Measles outbreak amplified in a pediatric ward: Lyantonde District, Uganda, August 2017
- date: 2020-06-05
- words: 3890
- flesch: 47
- summary: Measles vaccination is the best strategy for preventing measles outbreaks and achieving the goal of measles elimination. Measles vaccination is the best strategy for preventing measles outbreaks and achieving l measles elimination [9] .
- keywords: age; analysis; area; case; children; collection; conditional; control; data; days; department; district; dose; estimated; exposure; factors; health; hospital; investigation; isolation; logistic; lyantonde; measles; months; non; nosocomial; onset; outbreak; patients; pediatric; points; probable; public; rash; regression; risk; significant; study; symptoms; transmission; uganda; vaccination; vaccine; virus; ward; water; years
- versions: original; plain text
- cord-011671-7mki5dp9
- author: Fawaz, Sarah
- title: Comparing clinical outcomes of piperacillin-tazobactam administration and dosage strategies in critically ill adult patients: a systematic review and meta-analysis
- date: 2020-06-20
- words: 4931
- flesch: 38
- summary: Characteristics of included studies comprising of demographic characteristics, C/PI and II dosage, drug regimen treatment results as well as study outcomes and suggestions were extracted from all studies and summarised ( Table 2 ). One reviewer extracted the following data from included studies (S.F); the second and third reviewers verified the relevance of the extracted information (S.N-G and S.B).
- keywords: administration; adverse; analysis; antibiotic; bias; c.i; care; clinical; continuous; criteria; cure; data; dosing; drug; efficacy; events; extended; fig; heterogeneity; higher; hospital; infusion; intensive; intermittent; length; meta; microbiological; mortality; non; outcomes; participants; patients; piperacillin; piperacillintazobactam; prolonged; quality; rates; regimens; renal; results; review; sepsis; significant; stay; studies; study; systematic; table; tazobactam; treatment; trial
- versions: original; plain text
- cord-012875-joz31gie
- author: Weber, Katharina L.
- title: Simulating transmission of ESKAPE pathogens plus C. difficile in relevant clinical scenarios
- date: 2020-06-12
- words: 7123
- flesch: 44
- summary: Studying pathogen transfer under varying contact scenarios in a controlled manner is critical for understanding transmission and disinfectant strategies. We also explore the effect of various decontamination approaches on pathogen transfer between human subjects, such as the use of handwashing or surface disinfectants.
- keywords: aeruginosa; analysis; aureus; background; bacteria; cfu; community; concentration; contact; cotton; coupon; decontamination; differences; different; difficile; eskape+c; fig; fomite; hand; healthcare; high; higher; human; indirect; individual; initial; inoculated; inoculum; interaction; levels; log; low; method; microbial; nitrile; organism; overall; pathogen; pathogen transfer; percent; primary; rates; recovered; replicates; resistance; results; samples; scenarios; secondary; significant; simulated; skin; skin coupon; stainless; steel; step; sterile; studies; study; surface; synthetic; table; testing; total; transfer; transmission; vitro; washed; washing; water; way
- versions: original; plain text
- cord-012954-3x3rkor5
- author: Honkpehedji, Yabo Josiane
- title: Prospective, observational study to assess the performance of CAA measurement as a diagnostic tool for the detection of Schistosoma haematobium infections in pregnant women and their child in Lambaréné, Gabon: study protocol of the freeBILy clinical trial in Gabon
- date: 2020-09-29
- words: 5939
- flesch: 36
- summary: key: cord-012954-3x3rkor5 authors: Honkpehedji, Yabo Josiane; Adegnika, Ayôla Akim; Dejon-Agobe, Jean Claude; Zinsou, Jeannot Fréjus; Mba, Romuald Beh; Gerstenberg, Jacob; Rakotozandrindrainy, Raphaël; Rakotoarivelo, Rivo Andry; Rasamoelina, Tahinamandranto; Sicuri, Elisa; Schwarz, Norbert G.; Corstjens, Paul L. A. M.; Hoekstra, Pytsje T.; van Dam, Govert J.; Kreidenweiss, Andrea title: Prospective, observational study to assess the performance of CAA measurement as a diagnostic tool for the detection of Schistosoma haematobium infections in pregnant women and their child in Lambaréné, Gabon: study protocol of the freeBILy clinical trial in Gabon date: 2020-09-29 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05445-1 sha: doc_id: 12954 cord_uid: 3x3rkor5 BACKGROUND: The aim is to evaluate the accuracy of circulating anodic antigen (CAA) detection for diagnosis of Schistosoma haematobium infections in pregnant women and to validate CAA as an endpoint measure for anti-Schistosoma drug efficacy.
- keywords: accuracy; africa; age; analysis; anodic; antigen; areas; assay; available; birth; blood; caa; caa test; care; cca; children; clinical; control; data; day; delivery; detection; diagnostic; diseases; drug; effects; efficacy; egg; endemic; flow; freebily; gabon; group; haematobium; health; hrqol; infants; infected; infections; information; lambaréné; lateral; levels; lf caa; low; mansoni; maternal; measure; methods; microscopy; months; national; newborns; observational; outcomes; positive; praziquantel; pregnancy; pregnant; pregnant women; protocol; pzq; qpcr; randomised; reference; safety; sample; schistosoma; schistosomiasis; sensitive; sensitivity; set; specific; specificity; stool; studies; study; sub; test; time; treatment; trial; ucp; urine; use; women
- versions: original; plain text
- cord-025155-ow3r3469
- author: Lokida, Dewi
- title: Underdiagnoses of Rickettsia in patients hospitalized with acute fever in Indonesia: observational study results
- date: 2020-05-24
- words: 4443
- flesch: 39
- summary: United States: A Practical Guide for Physicians and Other Health-Care and Public Health Profesionals: CDC Diagnosis and management of tickborne rickettsial diseases: rocky mountain spotted fever and other spotted fever group rickettsioses, ehrlichioses, and anaplasmosis -United States State of the art of diagnosis of rickettsial diseases: the use of blood specimens for diagnosis of scrub typhus, spotted fever group rickettsiosis, and murine typhus Comparison of commercial enzyme-linked immunosorbent assay and immunofluorescence assay for diagnosis of acute Rickettsia typhi infections. Other fever studies revealed prevalence of murine typhus, spotted fever, and scrub typhus in Northeastern Papua to be 5, 1, and 3%, respectively [9] , whereas prevalence of murine typhus in Central Java was 7% [10] .
- keywords: acute; afire; antibiotics; assays; blood; cases; clinical; clinicians; common; convalescent; data; dengue; detection; diagnosis; disease; elisa; epidemiology; fever; fluorescence; fold; gene; group; hospitalization; human; ifa; igg; igm; illness; increase; indonesia; infection; laboratory; leptospira; leptospirosis; management; median; murine; negative; non; omp; ompb; patients; pcr; positive; r. typhi; rapid; reports; results; rickettsia; rickettsioses; scrub; specimens; studies; study; subjects; table; testing; tests; treatment; tsutsugamushi; typhi; typhoid; typhus
- versions: original; plain text
- cord-025163-iyh0d6mj
- author: Ding, Lin
- title: Early diagnosis and appropriate respiratory support for Mycoplasma pneumoniae pneumonia associated acute respiratory distress syndrome in young and adult patients: a case series from two centers
- date: 2020-05-24
- words: 4547
- flesch: 40
- summary: In one retrospective study from our hospital, 4.1% of M. pneumoniae pneumonia patients needed ICU admission for acute respiratory failure in the setting of an epidemic [21] . The rates of intensive care unit (ICU) admission of hospitalized M. pneumoniae pneumonia patients are reported as 10% in the US and 16.3% in Europe
- keywords: acute; admission; adult; appropriate; ards; cases; cell; clinical; cough; days; detection; diagnosis; distress; early; ecmo; effusion; failure; findings; fulminant; hfnc; high; hospital; icu; infection; lower; median; mmhg; mngs; mycoplasma; niv; onset; pao; patients; pcr; pleural; pneumoniae; pneumoniae pneumonia; previous; prone; rate; report; resistance; respiratory; review; samples; series; severe; sputum; study; support; syndrome; table; tract; treatment; ventilation; years
- versions: original; plain text
- cord-028945-p3hhd5ed
- author: Şahar, Esra Atalay
- title: Development of a hexavalent recombinant protein vaccine adjuvanted with Montanide ISA 50 V and determination of its protective efficacy against acute toxoplasmosis
- date: 2020-07-10
- words: 7386
- flesch: 48
- summary: Apart from these, multiplexing recombinant proteins induced strong and balanced Th1 and Th2 immune responses and improved protection against toxoplasmosis and thus showing the the importance of using multivalant recombinant protein vaccines in future vaccine development studies against ruminants, cats or humans. Recombinant protein vaccines are safe and efficient, and have a great potential for prevention or eradication of diseases.
- keywords: adjuvant; animals; antigenic; antigens; bioinformatics; candidate; cd4; cd8; cell; cellular; coli; control; cysts; development; elisa; epitopes; expression; fig; glycosylation; gondii; groups; hexavalent; hexavalent recombinant; higher; humans; humoral; ifn; igg; igg1; igg2a; il-4; immune; infection; isa; kda; lethal; levels; lymphocytes; mhc; mice; min; mixture; montanide; montanide isa; murine; parasite; pbs; protection; protein; protein mixture; protein vaccine; purified; ra4; ratio; rd6; re4; re6; recombinant; recombinant protein; response; results; rh2; rh6; rpm; sera; significant; sites; strain; strong; study; survival; t. gondii; table; tachyzoites; th1; tissue; total; toxoplasma; toxoplasmosis; usa; vaccinated; vaccination; vaccine
- versions: original; plain text
- cord-029423-o24dthlk
- author: Iwuji, Collins C.
- title: A phase IV randomised, open-label pilot study to evaluate switching from protease-inhibitor based regimen to Bictegravir/Emtricitabine/Tenofovir Alafenamide single tablet regimen in Integrase inhibitor-naïve, virologically suppressed HIV-1 infected adults harbouring drug resistance mutations (PIBIK study): study protocol for a randomised trial
- date: 2020-07-20
- words: 6727
- flesch: 38
- summary: After informed consent, but prior to initiation of study treatment, all SAEs and adverse events related to protocol-mandated procedures would be reported on the CRFs. Following initiation of study treatment, all AEs, regardless of cause or relationship until 30 days post cessation of trial treatment would be reported on the CRFs.
- keywords: activity; adults; adverse; alafenamide; analysis; antiretroviral; archived; arm; baseline; bictegravir; bpi; cardiovascular; clinical; confidence; consent; copies; data; days; dolutegravir; drug; drug resistance; efficacy; eligible; emtricitabine; events; failure; fdc; following; gilead; historical; hiv; individuals; infected; infection; information; inhibitor; investigator; label; line; m184v; methods; mutations; non; nrti; number; open; participants; patients; pilot; potential; presence; prior; procedures; protease; protocol; pvr; quality; randomisation; randomised; regimen; research; resistance; review; risk; rna; safety; scores; screening; second; single; sites; sleep; study; suppression; switch; symptom; taf; tams; tenofovir; therapy; time; treatment; trial; virological; visit; weeks
- versions: original; plain text
- cord-030134-drw6nqge
- author: Weerasooriya, Nilusha
- title: Staphylococcal endocarditis in a quadricuspid aortic valve following uncomplicated dengue infection: a case report
- date: 2020-08-06
- words: 1439
- flesch: 44
- summary: However, Staphylococcal endocarditis following dengue fever is uncommon. A 32-year-old Sri Lankan male presented to the National Hospital of Sri Lanka with recurrence of fever and acute left hemiplegia following an uncomplicated recovery of dengue fever.
- keywords: acute; aortic; case; clinical; complicated; day; dengue; endocarditis; fever; hospital; incidence; infection; infective; intravenous; lanka; left; linezolid; patient; qav; quadricuspid; report; rhabdomyolysis; sri; valve
- versions: original; plain text
- cord-031710-1xl2isee
- author: Andrei, Stefan
- title: Successful treatment of pulmonary haemorrhage and acute respiratory distress syndrome caused by fulminant Stenotrophomonas maltophilia respiratory infection in a patient with acute lymphoblastic leukaemia – case report
- date: 2020-09-10
- words: 2586
- flesch: 37
- summary: Stenotrophomonas maltophilia-induced pulmonary haemorrhage is considered a fatal infection among haematological patients. Stenotrophomonas maltophilia severe pneumonia complicated with pulmonary haemorrhage is not always fatal in haematological patients.
- keywords: abl; acute; admission; antibiogram; antibiotic; aplasia; ards; authors; blood; case; cell; chemotherapy; clinical; colistin; count; days; distress; fatal; fig; germ; haematological; haemorrhage; high; icu; infection; leukaemia; lymphoblastic; maltophilia; mdr; mortality; neutropenia; outcome; patient; pneumonia; positive; pulmonary; rate; ratio; respiratory; severe; smx; stenotrophomonas; syndrome; tmp; treatment
- versions: original; plain text
- cord-032382-5tp9i9vh
- author: Hackert, Volker H.
- title: Signs and symptoms do not predict, but may help rule out acute Q fever in favour of other respiratory tract infections, and reduce antibiotics overuse in primary care
- date: 2020-09-21
- words: 5646
- flesch: 39
- summary: During the Dutch epidemic of Q fever, general practitioners (GP's) with experience in treating Q fever patients tended to start empiric antibiotic therapy ahead of laboratory confirmation, which had a median delay of 20 days from onset of illness in 2009 key: cord-032382-5tp9i9vh authors: Hackert, Volker H.; Dukers-Muijrers, Nicole H. T. M.; Hoebe, Christian J. P. A. title: Signs and symptoms do not predict, but may help rule out acute Q fever in favour of other respiratory tract infections, and reduce antibiotics overuse in primary care date: 2020-09-21 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05400-0 sha: doc_id: 32382 cord_uid: 5tp9i9vh BACKGROUND: From early 2009, the Dutch region of South Limburg experienced a massive outbreak of Q fever, overlapping with the influenza A(H1N1)pdm09 pandemic during the second half of the year and affecting approximately 2.9% of a 300,000 population.
- keywords: acute; acute q; age; antibiotic; approach; burnetii; care; cases; clinical; community; complete; cough; data; diagnosis; disease; doxycycline; dutch; early; fever; holdout; hospital; infections; influenza; laboratory; low; march; medical; models; negative; netherlands; non; outbreak; patients; performance; phase; pneumonia; population; positive; prediction; predictors; presence; prevalence; primary; q fever; questionnaire; rate; regional; regression; respiratory; respondents; response; sample; second; signs; study; subjects; subsets; symptoms; testing; tract; treatment; use; validation; wave
- versions: original; plain text
- cord-033833-woref5g8
- author: Fragoso-Saavedra, Sergio
- title: A parallel-group, multicenter randomized, double-blinded, placebo-controlled, phase 2/3, clinical trial to test the efficacy of pyridostigmine bromide at low doses to reduce mortality or invasive mechanical ventilation in adults with severe SARS-CoV-2 infection: the Pyridostigmine In Severe COvid-19 (PISCO) trial protocol
- date: 2020-10-16
- words: 2761
- flesch: 32
- summary: In addition to the approved uses of i-ACh-e in human pathology, there is evidence in various murine models of their efficacy in experimental sepsis and severe inflammatory response [12, 19, 21] , suggesting that i-ACh-e drugs have a potential immunomodulatory effect in patients with severe systemic inflammatory response syndrome. key: cord-033833-woref5g8 authors: Fragoso-Saavedra, Sergio; Iruegas-Nunez, David A.; Quintero-Villegas, Alejandro; García-González, H. Benjamín; Nuñez, Isaac; Carbajal-Morelos, Sergio L.; Audelo-Cruz, Belem M.; Arias-Martínez, Sarahi; Caro-Vega, Yanink; Calva, Juan José; Luqueño-Martínez, Verónica; González-Duarte, Alejandra; Crabtree-Ramírez, Brenda; Crispín, José C.; Sierra-Madero, Juan; Belaunzarán-Zamudio, Pablo F.; Valdés-Ferrer, Sergio I. title: A parallel-group, multicenter randomized, double-blinded, placebo-controlled, phase 2/3, clinical trial to test the efficacy of pyridostigmine bromide at low doses to reduce mortality or invasive mechanical ventilation in adults with severe SARS-CoV-2 infection: the Pyridostigmine In Severe COvid-19 (PISCO) trial protocol date: 2020-10-16 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05485-7 sha: doc_id: 33833 cord_uid: woref5g8 BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative agent of coronavirus disease 2019 (COVID-19), may lead to severe systemic inflammatory response, pulmonary damage, and even acute respiratory distress syndrome (ARDS).
- keywords: ach; acute; adverse; analysis; associated; available; clinical; coronavirus; covid-19; day; days; death; disease; dsmb; events; group; infection; inflammation; inflammatory; instituto; invasive; mechanical; medical; mexico; mortality; nacional; need; nerve; outcome; participants; patients; phase; placebo; primary; protocol; pyridostigmine; randomized; respiratory; response; safety; sample; sars; severe; study; syndrome; systemic; test; trial; ventilation
- versions: original; plain text
- cord-035280-z0bbz19b
- author: Lee, Seung Hun
- title: First identification of Anaplasma phagocytophilum in both a biting tick Ixodes nipponensis and a patient in Korea: a case report
- date: 2020-11-11
- words: 3948
- flesch: 43
- summary: infection rates in ticks collected from migratory birds on Hongdo Island, Korea, A. phagocytophilum was detected in only 1 I. nipponensis nymph, among a total of 212 ticks (40 Haemaphysalis flava, 12 H. longicornis, 146 I. turdus, 13 I. nipponensis, and 1 I. ornithophilia) A. phagocytophilum has previously been identified in three tick species (H. longicornis, I. persulcatus, and I. nipponensis) in Korea, but no direct transmission from ticks to humans has been confirmed.
- keywords: accession; admission; analysis; anaplasma; anaplasmosis; antibodies; bite; blood; borrelia; burgdorferi; case; cells; culture; days; detection; disease; dna; fever; fig; gene; granulocytic; hga; human; identification; igm; infected; infection; ixodes; korea; level; longicornis; molecular; nipponensis; patient; pcr; persulcatus; phagocytophilum; phylogenetic; positive; primers; reaction; results; rickettsia; sequences; specific; specimen; spp; states; strain; study; tick; tree; tsutsugamushi; typhi; united; usa; vector
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- cord-048467-1dus0u4m
- author: Civaner, Murat
- title: Can "presumed consent" justify the duty to treat infectious diseases? An analysis
- date: 2008-03-06
- words: 7746
- flesch: 48
- summary: Moreover, as described above, the decision to quit medical school can be quite difficult: on one side of the dilemma there are occupational risks that must be accepted regardless of misgivings on the part of the individual; on the other side, very influential factors pressure the individual to continue their medical education. And, needless to say, such risks do indeed at times prove fatal.
- keywords: aids; argument; attitudes; available; aware; care; choice; consent; consent argument; contagious; criteria; dentists; diseases; duty; education; factors; faculty; hcws; health; health care; hiv; important; individual; infection; informed; knowledge; level; measures; medical; medical profession; moral; occupational; occupational risks; opinions; order; participants; particular; patients; person; physicians; possible; practice; profession; protective; question; questionnaire; risks; sars; slr; study; time; training; treatment; uncertainty; understanding; workers; working
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- cord-048489-ajafw966
- author: Bozza, Fernando A
- title: Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity
- date: 2008-06-25
- words: 4939
- flesch: 41
- summary: R Foundation for Statistical Computing Activation of T lymphocytes in dengue virus infections. Chemotaxis, Ca2+ mobilization, and enzyme release Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis Elevated tumour necrosis factor in dengue fever and dengue haemorrhagic fever Plasma levels of tumour necrosis factor alpha and transforming growth factor beta-1 in children with dengue 2 virus infection in French Polynesia Correlation Of Serum Levels Of Macrophage Migration Inhibitory Factor With Disease Severity And Clinical Outcome In Dengue Patients Characterisation of lymphocyte response and cytokine patterns in patients with dengue fever Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections Th(2) immune response in patients with dengue during defervescence: preliminary evidence Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes Dengue-specific T cell responses in peripheral blood mononuclear cells obtained prior to secondary dengue virus infections in Thai schoolchildren Alternative activation of macrophages Effects of granulocyte-monocyte colony-stimulating factor (GM-CSF) on expression of adhesion molecules and production of cytokines in blood monocytes and ovarian cancer-associated macrophages MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers Predictors of spontaneous bleeding in Dengue Dengue and dengue hemorrhagic fever, Brazil Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS)
- keywords: activation; alpha; analysis; assay; authors; bio; blood; cases; cells; clinical; correlation; csf; cytokine; data; defervescence; dengue; dhf; diagnosis; different; disease; earlier; early; endothelial; factors; fever; figure; forms; good; haemorrhagic; hypotension; ifn; il-1β; il-6; immune; increase; infection; inflammatory; leakage; levels; manifestations; mcp-1; mild; mip-1β; models; monocytes; multiplex; order; outcome; patients; permeability; phase; plasma; present; production; profiles; related; response; role; samples; secondary; severe; severity; specific; statistical; studies; study; table; test; thrombocytopenia; time; tnf; viral; virus
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- cord-252304-lwiulri7
- author: Fragnoud, Romain
- title: Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue
- date: 2015-11-14
- words: 8329
- flesch: 42
- summary: As the dynamic range for plasma proteins is large (over 10 orders of magnitude) and the most abundant proteins (0.1 % of the total number) constitute up to 95 % of the plasmatic protein mass, identification of biomarkers present at low concentrations is a major challenge in proteomic studies dealing with plasma. ELISAs were used to validate differential expression of a selection of identified host proteins in individual plasma samples of patients with dengue fever compared to patients with severe dengue.
- keywords: activation; acute; additional; analysis; blood; c1r; cambodian; cell; cellular; coagulation; colombian; complement; concentration; control; culture; dengue; dengue patients; dengue virus; different; disease; elisas; endothelial; expression; factor; fever; fig; file; fraction; france; gel; hemorrhagic; hepg2; higher; host; host proteins; human; identification; immune; individual; infected; infection; interactions; ipa; kit; levels; markers; mass; ns1; number; olfm4; particles; pathogenesis; pathogenicity; pathway; patients; pbs; peptides; pf4; phase; plasma; plasma samples; platelet; pooled; pools; potential; present; proteins; proteomic; purification; purified; ratio; response; results; role; samples; sd patients; sd plasma; serum; severe; severe dengue; severity; shock; signaling; software; step; studies; study; supernatant; symptoms; system; table; technique; test; ultracentrifugation; usa; viral; viremia; virions; virus; viruses
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- cord-253171-l56qcbat
- author: Rao, Huaxiang
- title: Using the Kulldorff’s scan statistical analysis to detect spatio-temporal clusters of tuberculosis in Qinghai Province, China, 2009–2016
- date: 2017-08-21
- words: 4108
- flesch: 51
- summary: We collected data (2009-2016) of TB cases in Qinghai from the China Information System for Disease Control and Prevention (CISDCP). The total number of TB cases was 5408, and the risk of TB related incidents was 2.97 times (RR = 3.97) higher than that outside this area (Table 2 and Additional file 1: Fig. S2 ).
- keywords: analysis; areas; authors; autocorrelation; cases; china; cluster; clustering; control; counties; county; data; disease; distribution; fig; high; incidence; incidents; kulldorff; level; likely; maximum; method; model; period; population; prevention; province; qinghai; radius; results; risk; scan; scanning; seasonal; significant; size; space; spatial; spatio; statistical; study; tb incidents; temporal; time; total; tuberculosis; window
- versions: original; plain text
- cord-256094-f85xc5uu
- author: Milinovich, Gabriel J
- title: Using internet search queries for infectious disease surveillance: screening diseases for suitability
- date: 2014-12-31
- words: 4966
- flesch: 40
- summary: Infectious diseases surveillance systems have been developed using internet search metrics to estimate incidence of influenza (Google Flu Trends) Combined, these features of internet usage and availability, infectious disease surveillance systems and diseases susceptibility patterns make Australia an ideal system in which to study the potential application of internet-based surveillance systems.
- keywords: analyses; approach; australia; community; correlations; cross; data; dengue; development; diseases; early; events; figure; flu; forecasting; frequency; google; health; infectious; influenza; information; interest; internet; lag; level; metrics; models; monitoring; monthly; national; notifiable; notifications; period; positive; potential; preventable; range; rank; related; results; search; searches; series; significant; spearman; state; study; surveillance; systems; terms; time; traditional; trends; use; vaccine; value; vector; virus; warning
- versions: original; plain text
- cord-258611-uzzs8w1j
- author: Ma, Xuezheng
- title: No MERS-CoV but positive influenza viruses in returning Hajj pilgrims, China, 2013–2015
- date: 2017-11-10
- words: 2150
- flesch: 48
- summary: In this study, we did not detect any cases of MERS-CoV infection but respiratory virus infections including influenza A and B, hMPV, hRSV, and human coronavirus were detected among Hajj pilgrims returning to China. Our sampling design would therefore include some healthy pilgrims, thereby decreasing the rate of detection of respiratory virus infections.
- keywords: china; coronavirus; cov; detection; difference; east; entry; fever; hajj; health; human; infection; influenza; mecca; mers; middle; participants; pilgrims; positive; rates; respiratory; results; samples; saudi; study; syndrome; time; travelers; vaccination; virus; viruses
- versions: original; plain text
- cord-259667-x51jorbm
- author: Chughtai, Abrar Ahmad
- title: Contamination by respiratory viruses on outer surface of medical masks used by hospital healthcare workers
- date: 2019-06-03
- words: 4274
- flesch: 52
- summary: Used medical masks were collected at the end of the day and were stored immediately in zip-lock bags. To our knowledge this is the first study examining the presence of respiratory viruses on the outer surface of used medical masks.
- keywords: care; china; clinical; contact; contamination; control; data; diseases; duration; equipment; hcws; health; healthcare; high; higher; hospital; infection; influenza; laboratory; main; masks; maximum; medical; middle; number; outer; pandemic; participants; pathogens; patients; personal; pilot; positive; positivity; presence; protective; research; respiratory; risk; samples; sections; self; settings; studies; study; surface; testing; time; upper; use; virus; viruses; workers
- versions: original; plain text
- cord-260550-ld9eieik
- author: Ng, Man Wai
- title: The association of RANTES polymorphism with severe acute respiratory syndrome in Hong Kong and Beijing Chinese
- date: 2007-06-01
- words: 2850
- flesch: 55
- summary: SARS study group: Coronavirus as a possible cause of severe acute respiratory syndrome Severe acute respiratory syndrome Pathogenesis of severe acute respiratory syndrome Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection Association between mannose-binding lectin gene polymorphisms and susceptibility to severe acute respiratory syndrome coronavirus infection The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes : a case-control study Chemokine regulation of inflammation during acute viral infection Chemokine upregulation in SARS coronavirus infected human monocyte derived dendritic cells Defense against influenza A virus infection : essential role of the chemokine system Polymorphisms in the promoter region of RANTES and the regulatory region of monocyte chemoattractant protein-1 among Chinese Children with systemic lupus erythematosus Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils Nuclear factor-kappa B potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression Chemokines -chemotactic cytokines that mediate inflammation RANTES: a versatile and controversial chemokine Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome Genetic relationship of populations in China Towards a genetic history of China The genotype frequencies and allele frequencies of all the genes were compared between SARS patients and controls by a 3 × 2 chi-square test and a 2 × 2 chi-square test respectively, then logistic regression was used for calculating odds ratios (95% confidence interval) and corresponding P-values of different genotype frequencies among SARS patients and controls by adjusting for age, sex and all significant single nucleotide polymorphisms (SNPs).
- keywords: -28; acute; age; allele; association; beijing; cells; chemokine; chinese; controls; coronavirus; death; fold; frequencies; gene; genotype; group; hong; infection; kong; mean; patients; polymorphisms; rantes; respiratory; risk; sars; severe; significant; study; susceptibility; syndrome; table
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- cord-261251-ylvqxpba
- author: Ansuini, Valentina
- title: Debate around infection-dependent hemophagocytic syndrome in paediatrics
- date: 2013-01-16
- words: 4651
- flesch: 13
- summary: Familial hemophagocytic lymphohistiocytosis and viral infections Familial haemophagocytic reticulosis Incidence in Sweden and clinical features of familial hemophagocytic lymphohistiocytosis Clinical and epidemiologic studies of familial hemophagocytic lymphohistiocytosis in Japan Hemophagocytic lymphohistiocytosis: diagnosis, pathophysiology, treatment, and future perspectives Hemophagocytic syndromes and infection Large pericardial effusion requiring pericardiocentesis as cardinal sign of macrophage activation syndrome in systemic onsetjuvenile idiopathic arthritis First report of macrophage activation syndrome in hyperimmunoglobulinemia D with periodic fever syndrome Infection and malignancy associated hemophagocytic syndromes. key: cord-261251-ylvqxpba authors: Ansuini, Valentina; Rigante, Donato; Esposito, Susanna title: Debate around infection-dependent hemophagocytic syndrome in paediatrics date: 2013-01-16 journal: BMC Infect Dis DOI: 10.1186/1471-2334-13-15 sha: doc_id: 261251 cord_uid: ylvqxpba BACKGROUND: Hemophagocytic syndrome (HPS) is clinically defined as a combination of fever, liver dysfunction, coagulation abnormalities, pancytopenia, progressive macrophage proliferation throughout the reticuloendothelial system, and cytokine over-production, and may be primary or secondary to infectious, auto-immune, and tumoral diseases.
- keywords: activation; acute; agents; anti; association; b19; barr; better; bone; cases; cause; cell; chain; children; clinical; cmv; corticosteroids; cytokine; diagnosis; disease; disorders; dysfunction; ebv; epstein; familial; fatal; fever; forms; genetic; h5n1; hemophagocytic; hemophagocytic lymphohistiocytosis; hemophagocytic syndrome; hepatitis; high; hiv; host; hps; human; immune; immunodeficiency; immunoglobulin; infected; infection; inflammatory; influenza; intravenous; laboratory; leishmania; lymphocytes; lymphohistiocytosis; macrophage; marrow; non; parvovirus; patients; primary; process; production; prognosis; proliferation; related; report; review; secondary; severe; specific; spp; study; syndrome; system; therapy; transplantation; treatment; underlying; viral; virus
- versions: original; plain text
- cord-261756-4lybl57r
- author: Dubert, Marie
- title: Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function
- date: 2020-02-24
- words: 4190
- flesch: 40
- summary: The pathogenesis and management of influenza virus infection in organ transplant recipients Incidence and morbidity of human metapneumovirus and other community-acquired respiratory viruses in lung transplant recipients Rhinovirus and other respiratory viruses exert different effects on lung allograft function that are not mediated through acute rejection Respiratory virus infections and chronic lung allograft dysfunction: assessment of virology determinants Symptomatic respiratory virus infection and chronic lung allograft dysfunction Viral respiratory tract infection during the first postoperative year is a risk factor for chronic rejection after lung transplantation Respiratory viruses in lung transplant recipients: a critical review and pooled analysis of clinical studies The epidemiology of parainfluenza virus infection in lung transplant recipients Human metapneumovirus infection in lung transplant recipients: clinical presentation and epidemiology Upper and lower respiratory tract viral infections and acute graft rejection in lung transplant recipients Development of a respiratory virus panel test for detection of twenty human respiratory viruses by use of multiplex PCR and a fluid microbeadbased assay Incidence and outcomes of respiratory viral infections in lung transplant recipients: a prospective study Comparison of the Luminex xTAG Therefore, it seems important to assess the impact of respiratory viral infections on the graft function: to emphasize the prevention of viral infections for immunocompromised with more frequent sampling of patients including wide respiratory virus detection by molecular techniques and to strengthen spirometric controls after viral infections.
- keywords: acute; analysis; association; bacterial; big; bos; bronchiolitis; chronic; clinical; data; death; detection; development; different; dysfunction; function; graft; groups; impact; inclusion; infected; infections; late; ltrs; lung; manuscript; months; obliterans; patients; period; positive; prior; rate; recipients; rejection; respiratory; risk; samples; similar; studies; study; transplantation; transplants; vig; viral; virological; viruses; vrti; writting
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- cord-262646-64ldtrjf
- author: Chuang, Pei-Hung
- title: A dynamic estimation of the daily cumulative cases during infectious disease surveillance: application to dengue fever
- date: 2010-05-27
- words: 4153
- flesch: 52
- summary: i = 1) by calculating the proportion of confirmed positive dengue cases out of the suspect cases using the data with onset date within 1 year before the date c. Based on a parametric approach, we assumed the OC-time for a given case status, P(T|y i ), follow a gamma distribution. In this article, we use confirmed dengue cases and positive cases interchangeably.
- keywords: cases; confirmation; confirmed; cumulative; cumulative cases; curve; daily; data; date; dengue; dengue cases; diagnosis; disease; distribution; epidemic; estimate; fever; final; gamma; infectious; laboratory; method; new; new cases; nonparametric; number; onset; positive; positive cases; probability; real; results; status; study; surveillance; suspect; suspect cases; taiwan; time
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- cord-267090-jc1k3fki
- author: Gardner, Emma G.
- title: A case-crossover analysis of the impact of weather on primary cases of Middle East respiratory syndrome
- date: 2019-02-04
- words: 4365
- flesch: 45
- summary: A case-crossover design was used to identify associations between primary MERS cases and preceding weather conditions within the 2-week incubation period in Saudi Arabia using univariable conditional logistic regression. A case-crossover design was used to explore the associations between primary MERS cases and preceding meteorological conditions [17, 26] .
- keywords: acute; air; arabia; camels; cases; conditions; coronavirus; cov; crossover; daily; data; days; design; disease; dromedary; east; environmental; events; evidence; exposure; health; high; human; humidity; infections; influenza; lags; low; maximum; mean; mers; middle; minimum; odds; onset; period; pollution; primary; province; respiratory; results; risk; saudi; similar; speed; study; syndrome; temperature; time; transmission; virus; visibility; weather; wind; world; zoonotic
- versions: original; plain text
- cord-269772-4zrmsw2f
- author: Liu, Ming-Der
- title: Changing risk awareness and personal protection measures for low to high pathogenic avian influenza in live-poultry markets in Taiwan, 2007 to 2012
- date: 2015-06-24
- words: 7729
- flesch: 44
- summary: Human infection with avian influenza A H6N1 virus: an epidemiological analysis Knowledge and anticipated attitudes of the community about bird flu outbreak in Turkey Knowledge, attitudes and practices (KAP) relating to avian influenza in urban and rural areas of China Global alert to avian influenza virus infection: From H5N1 to H7N9 Hong Kong places curbs on market poultry Physical interventions to interrupt or reduce the spread of respiratory viruses attitudes, and practices regarding avian influenza (H5N1) Avoiding the risk of infection when working with poultry that is suspected of having H5 or H7 notifiable avian influenza Effectiveness of personal protective equipment and oseltamivir prophylaxis during avian influenza A (H7N7) epidemic, the Netherlands Self-reported use of personal protective equipment among Chinese critical care clinicians during 2009 H1N1 influenza pandemic Barriers to vaccinating the elderly with H1N1 vaccine Why do I need it? To increase the sample size for the areas with LPAI H5N2 outbreaks, which is the most neglected and important issue to be addressed, we covered all the major LPMs in the outbreak areas and asked as many people as possible to answer the questions at each study site.
- keywords: additional; aivs; analyses; appendix; areas; attitudes; avian; avian influenza; awareness; better; cases; central; chickens; china; community; crs; data; differences; different; education; factors; file; government; groups; h5n1; h5n2; h5n2 outbreaks; h7n9; health; high; higher; hong; hpai; hpai h5n2; hpai outbreaks; human; important; infection; influenza; information; knowledge; kong; live; low; lower; lpai; lpaivs; lpmws; markets; measures; outbreaks; pathogenic; pathogenicity; perception; personal; policies; policy; poultry; preventive; protection; public; question; questionnaire; rap; residents; respondents; results; risk; risk awareness; slaughtering; stage; study; survey; table; taiwan; vaccine; variables; viruses; workers
- versions: original; plain text
- cord-271105-eyigl0wz
- author: Ionidis, Georgios
- title: Development and virucidal activity of a novel alcohol-based hand disinfectant supplemented with urea and citric acid
- date: 2016-02-11
- words: 5004
- flesch: 41
- summary: According to the Guideline of the DVV/RKI, a formulation under test conditions must give at least a 4.0 log 10 reduction in infectivity titer of test virus (inactivation ≥ 99.99 %) at the recommended concentration and exposure time to be considered active [22, 34] . Tests according to EN 14476 were run in parallel to the Guideline of DVV/RKI with PV, AdV and MNV as test viruses of the EN 14476 and the corresponding permissive cells The different formulations of the new hand rub based on ethanol, citric acid and urea were screened undiluted (80.0 % due to the addition of test virus suspension and interfering substance) against PV, AdV and polyomavirus SV40 as non-enveloped test viruses of the Guideline of DVV/RKI in the presence of FCS with a fixed exposure time of 60 s. The ethanol and 2-propanol amounts were constant (69.39 % w/w and 3.69 % w/w, respectively) in these assays while citric acid and urea were used in a dosedependent manner.
- keywords: acid; active; activity; addition; adv; alcohol; broad; carrier; citric; citric acid; claim; concentration; conditions; control; der; different; disinfectants; dvv; effect; efficacy; enveloped; ethanol; exposure; fcs; fig; fingerpad; formulation; german; guideline; hand; human; hygiene; inactivated; inactivation; log; method; mnv; new; non; norovirus; polyomavirus; presence; quantitative; reduction; results; rki; rubs; spectrum; stainless; sufficient; suspension; sv40; table; test; testing; time; urea; vaccinia; viral; virucidal; viruses; water; zur
- versions: original; plain text
- cord-271813-nroflfmc
- author: Deng, Wang
- title: Positive results for patients with COVID-19 discharged form hospital in Chongqing, China
- date: 2020-06-19
- words: 2428
- flesch: 41
- summary: In addition, there is a lack of clinical characteristics, the potential impact and significance of positive patients recovered from COVID-19, which makes it difficult to provide clinical evidence and experience for the management of patients with COVID-19 in the recovery period. With the increasing number of recovered patients, more attention should be paid to the follow-up of these patients.
- keywords: acid; asymptomatic; china; clinical; coronavirus; cov-2; covid-19; days; detection; diagnosis; discharged; disease; hospital; infection; management; medical; nasal; negative; nucleic; patients; pcr; pharyngeal; positive; quarantine; recovered; respiratory; results; sars; specimens; sputum; stool; study; swabs; treatment; viral
- versions: original; plain text
- cord-272194-h7xnr389
- author: Wiegers, Hanke M. G.
- title: Bacterial co-infection of the respiratory tract in ventilated children with bronchiolitis; a retrospective cohort study
- date: 2019-11-06
- words: 3792
- flesch: 40
- summary: In this large and concise study on bacterial co-infections in children with bronchiolitis we have found that bacterial infections are common, associated with prolonged ventilation and a raised CRP. Risk of bacterial infection in previously healthy respiratory syncytial virus-infected young children admitted to the intensive care unit The use of C-reactive protein in predicting bacterial co-infection in children with bronchiolitis Bacteraemia and antibiotic use in respiratory syncytial virus infections Pediatric investigators collaborative network on infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis Pulmonary and systemic bacteria co-infections in severe RSV bronchiolitis Concurrent bacterial infection and prolonged mechanical ventilation in children with respiratory syncytial virus lower respiratory tract disease Empiric antibiotics are justified for children with respiratory syncytial virus lower respiratory tract infection presenting with respiratory failure: a prospective study and evidence review Development and evaluation of a four-tube real time multiplex PCR assay covering fourteen respiratory viruses, and comparison to its corresponding single target counterparts Azithromycine does not improve disease course in hospitilized children with respiratory syncytial virus (RSV) lower respiratory tract disease: a randomized equivalence trial Infectious Diseases Society of America.
- keywords: antibiotics; bacterial; bacterial co; bronchiolitis; cfu; children; clinical; common; crp; cultures; data; days; disease; duration; growth; infection; invasive; late; longer; low; mechanical; negative; pathogens; patients; picu; prevalence; previous; respiratory; retrospective; rsv; sampling; severe; stay; studies; study; syncytial; table; tract; use; ventilation; viral; virus
- versions: original; plain text
- cord-272207-jtvf257r
- author: Liao, Qiuyan
- title: Anxiety, worry and cognitive risk estimate in relation to protective behaviors during the 2009 influenza A/H1N1 pandemic in Hong Kong: ten cross-sectional surveys
- date: 2014-03-27
- words: 4991
- flesch: 30
- summary: Associations between cognitive risk perception measures and protective action were quite inconsistent across the ten selected surveys in this study. In the early epidemic stage when uncertainty about the epidemic characteristics, treatment and prevention is higher, affective responses may be optimal for guiding behavioral change [6, 9, 10] but cognitive risk responses should increasingly drive behavior as the epidemic evolves.
- keywords: absolute; additional; adoption; affective; anxiety; associated; associations; behaviors; change; cognitive; cross; current; data; different; epidemic; estimates; figure; file; general; h1n1; health; hong; household; influenza; items; kong; measures; missing; pandemic; perception; periods; personal; population; proportions; protective; protective behaviors; psychological; relative; respondents; responses; rides; risk; s13; sars; sectional; severity; state; studies; study; surveys; susceptibility; table; worry
- versions: original; plain text
- cord-272240-s1gnwb2s
- author: Li, Tiegang
- title: Attitudes, practices and information needs regarding novel influenza A (H7N9) among employees of food production and operation in Guangzhou, Southern China: a cross-sectional study
- date: 2014-01-02
- words: 5158
- flesch: 49
- summary: Taken together, despite these limitations, our study provides valuable insight into attitudes and practices related to H7N9 influenza among employees of food production and operation just three months after the first human infection case reported in China, and one month after chickens were found to be infected in Guangzhou. Multivariate logistic regression analyses were used to clarify the relationship between different methods of obtaining H7N9 information and demographic variables, and to identify the significant independent predictors of acceptance of a H7N9 vaccine, by calculating odds ratios (OR) after controlling for gender, age, and other demographics.
- keywords: age; associated; attitudes; available; avian; china; control; disease; education; employees; epidemic; females; food; government; guangzhou; h1n1; h7n9; health; higher; human; infected; infection; influenza; information; internet; kong; likely; measures; methods; model; months; needs; novel; operation; options; pandemic; participants; poultry; practices; preventive; production; public; related; response; results; study; survey; vaccination; vaccine; variables; virus; willingness; worried; years
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- cord-274123-wgigtgl9
- author: Dube, Felix S.
- title: Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa
- date: 2016-10-24
- words: 4264
- flesch: 38
- summary: Further, PTB has increasingly been reported in children presenting with acute pneumonia; culture confirmed TB was reported in 8 % of South African children hospitalized with acute pneumonia with no difference by HIV status [6] . In our studies of South African children hospitalised with suspected PTB, 16 % of children hospitalised with suspected PTB had microbiologically-confirmed PTB, 48 % were classified as unconfirmed-PTB and 37 % were classified as unlikely-PTB (children in whom TB was excluded and who improved in the absence of TB therapy)
- keywords: acid; additional; adenovirus; africa; age; analysis; available; bacteria; cape; catarrhalis; children; clinical; common; confirmed; coronavirus; culture; cytomegalovirus; definite; detection; discriminant; file; groups; health; hiv; hmpv; hospital; infection; influenza; lower; lrti; microbes; nasopharyngeal; nasopharynx; nucleic; pathogens; pertussis; pneumoniae; potential; ptb; pulmonary; respiratory; rhinovirus; role; samples; significant; south; specimens; spp; study; symptoms; table; targets; town; tract; tuberculosis; unlikely; viral; virus; viruses
- versions: original; plain text
- cord-274438-tgslabi2
- author: Schnee, Sarah Valerie
- title: Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children
- date: 2017-12-13
- words: 3124
- flesch: 48
- summary: Expert review of respiratory medicine Lack of sensitivity of rapid antigen tests for the diagnosis of respiratory syncytial virus infection in adults Diagnostic accuracy of rapid antigen detection tests for respiratory Syncytial virus infection: systematic review and meta-analysis Evaluation of Alere i RSV for rapid detection of respiratory syncytial virus in children hospitalized with acute respiratory tract infection Alere i RSV test results are available A limitation of our study is the use of VTM for Alere i RSV testing instead of directly inserting the swab to the Alere test base.
- keywords: acute; age; alere; analysis; assay; care; children; ci(95; clinical; data; detection; ftd; infection; influenza; load; min; negative; patients; pcr; pediatric; point; positive; radt; rapid; reference; respiratory; results; rsv; samples; sensitivity; setting; specificity; standard; study; syncytial; test; testing; tract; viral; virus; young
- versions: original; plain text
- cord-274749-ji91qq9q
- author: Lagare, Adamou
- title: Viral and bacterial etiology of severe acute respiratory illness among children < 5 years of age without influenza in Niger
- date: 2015-11-14
- words: 3583
- flesch: 44
- summary: Submit your manuscript at www.biomedcentral.com/submit Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis Estimate of worldwide distribution of child deaths from acute respiratory infections Respiratory viruses seasonality in children under five years of age in Viral etiologies of lower respiratory tract infections among Egyptian children under five years of age Respiratory viral coinfections identified by a 10-plex real-time reversetranscription polymerase chain reaction assay in patients hospitalised with severe acute respiratory illness-South Africa Viral etiology of influenza-like illness in Cameroon Clinical utility of PCR common viruses in acute respiratory illness Microbial aetiology of community-acquired pneumonia in hospitalised patients Clinico-pathological study of atypical pathogens in community-acquired pneumonia: a prospective study Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children Carriage of Streptococcus pneumoniae and other respiratory bacterial pathogens in low and lower-middle income countries: a systematic review and meta-analysis Viral and bacterial detection in acute respiratory infection in children under five years Sentinel surveillance of influenza and other respiratory viruses, Brazil Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis Viral etiology of acute respiratory tract infection among pediatric inpatients and outpatients from 2010 to 2012 in Beijing, China Viral and atypical bacterial etiology of acute respiratory infections in children under 5 years old living in rural tropical area of Madagascar Viral etiology of respiratory infections in children under 5 years old living in tropical rural areas of Senegal: Nasopharyngeal specimens may be used to aid in the diagnosis of certain bacterial respiratory pathogens that do not tend to colonize the nasopharynx, such as M. pneumoniae and C. pneumoniae
- keywords: acute; africa; age; bacterial; cases; children; december; detection; disease; etiology; hib; high; hmpv; illness; infections; influenza; lower; nasopharyngeal; national; niger; pathogens; patients; piv; pneumoniae; positive; prevalence; rate; respiratory; rsv; samples; sari; season; selected; sentinel; severe; specimens; studies; study; surveillance; tract; type; viral; virus; viruses; years
- versions: original; plain text
- cord-274763-i6e3g3te
- author: Liu, Wen-Kuan
- title: Epidemiology of HBoV1 infection and relationship with meteorological conditions in hospitalized pediatric patients with acute respiratory illness: a 7-year study in a subtropical region
- date: 2018-07-16
- words: 3462
- flesch: 41
- summary: Cloning of a human parvovirus by molecular screening of respiratory tract samples Human Parvoviruses Virological and clinical characterizations of respiratory infections in hospitalized children Detection of human bocavirus type 1 infection in Panamanian children with respiratory illness Detection of human bocavirus in nasopharyngeal aspirates versus in broncho-alveolar lavage fluids in children with lower respiratory tract infections Human bocavirus detection in nasopharyngeal aspirates of children without clinical symptoms of respiratory infection Detection of bocavirus in saliva of children with and without respiratory illness B-cell responses to human Bocaviruses 1-4: new insights from a childhood follow-up study Seroepidemiology of human bocavirus defined using recombinant viruslike particles Seroepidemiology of human bocaviruses 1-4 The genomic and seroprevalence of human bocavirus in healthy Chinese plasma donors and plasma derivatives Human bocavirus: current knowledge and future challenges Spontaneous pneumomediastinum as a complication in human bocavirus infection Human bocavirus-the first 5 years Detection of human bocavirus from children and adults with acute respiratory tract illness in Guangzhou, southern China Comorbidity and high viral load linked to clinical presentation of respiratory human bocavirus infection Epidemic and molecular evolution of human bocavirus in hospitalized children with acute respiratory tract infection Human bocavirus amongst an all-ages population hospitalised with acute lower respiratory infections in Cambodia. Influenza Other Respir Viruses Human bocavirus in Chile: clinical characteristics and epidemiological profile in children with acute respiratory tract infections Single detection of human bocavirus 1 with a high viral load in severe respiratory tract infections in previously healthy children Human bocavirus as the cause of a life-threatening infection Clinical and microbiological impact of human bocavirus on children with acute otitis media Severe human bocavirus infection Clinical epidemiology and molecular profiling of human bocavirus in faecal samples from children with diarrhoea in Guangzhou Human bocavirus and acute wheezing in children Prevalence and clinical aspects of human bocavirus infection in children High incidence of human bocavirus infection in children in Spain Correlation between bocavirus infection and humoral response, and co-infection with other respiratory viruses in children with acute respiratory infection Human bocavirus in patients with encephalitis Identification of human bocaviruses in the cerebrospinal fluid of children hospitalized with encephalitis in China Detection of human bocavirus in the cerebrospinal fluid of children with encephalitis Detection and quantification of human bocavirus in river water Mixed viral infections causing acute gastroenteritis in children in a waterborne outbreak Frequent detection of highly diverse variants of cardiovirus, cosavirus, bocavirus, and circovirus in sewage samples collected in the United States In vitro modeling of human bocavirus 1 infection of polarized primary human airway epithelia Establishment of a reverse genetics system for studying human bocavirus in human airway epithelia Human bocavirus 1 infects commercially available primary human airway epithelium cultures productively Are meteorological parameters associated with acute respiratory tract infections?
- keywords: acute; age; analysis; ari; bocavirus; children; china; clinical; common; conditions; current; data; detection; different; epidemiology; fig; guangzhou; hbov1; high; hospitalized; human; humidity; infection; mean; meteorological; model; monthly; old; pathogens; patients; positive; pressure; prevalence; relative; respiratory; samples; study; subtropical; table; temperature; tract; viruses; years
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- cord-275211-1b56a6zc
- author: Liu, Wen-Kuan
- title: Epidemiology and clinical presentation of the four human parainfluenza virus types
- date: 2013-01-23
- words: 3238
- flesch: 50
- summary: HPIV infection led to a wide spectrum of symptoms, and more “hoarseness” (p=0.015), “abnormal pulmonary breathing sound” (p<0.001), “dyspnoea” (p<0.001), “pneumonia” (p=0.01), and “diarrhoea” (p<0.001) presented in HPIV-positive patients than HPIV-negative patients. HPIV infection led to a wide spectrum of symptoms, and similar clinical manifestations were found in the patients with four different types of HPIVs.
- keywords: acute; adults; age; children; china; clinical; common; different; hpiv; hpiv-3; human; illness; infected; infection; like; lrti; month; negative; old; p<0.001; parainfluenza; pathogens; patients; positive; presentation; previous; respiratory; samples; significant; study; symptoms; systemic; table; tract; types; virus; years
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- cord-276015-id15u3br
- author: Beran, Jiří
- title: Inosine pranobex is safe and effective for the treatment of subjects with confirmed acute respiratory viral infections: analysis and subgroup analysis from a Phase 4, randomised, placebo-controlled, double-blind study
- date: 2016-11-07
- words: 6094
- flesch: 41
- summary: Thus, the efficacy of inosine pranobex was improved in nonobese subjects compared with obese subjects, probably because the immune system in the former is more capable of defending against pathogens and is not negatively affected by obesity-related complications. The safety analysis demonstrated that inosine pranobex treatment was well tolerated, and no major differences in safety profiles were observed between treatment groups.
- keywords: acute; additional; age; analysis; assessment; baseline; bmi; clinical; day; days; difference; disease; dose; drug; efficacy; endpoints; enrolment; file; group; ili; immune; improvement; infections; influenza; inosine; inosine pranobex; like; like symptoms; medical; mild; mitt; non; obese; obesity; observed; ongoing; pathogens; placebo; placebo group; pranobex; pranobex group; present; primary; related; resolution; respiratory; response; results; safety; season; secondary; set; severe; significant; study; subgroup; subjects; symptoms; system; time; treatment; vaccine; viral; virus; years
- versions: original; plain text
- cord-276857-i948aq4b
- author: Chung, Grace TY
- title: A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study
- date: 2005-10-18
- words: 2335
- flesch: 44
- summary: Koch's postulates fulfilled for SARS virus Genotype of SARS-CoV culture isolates from 30 patients determined by Taqman Allelic Discrimination assays Petric M, Skowronski DM Characterization of a novel coronavirus associated with severe acute respiratory syndrome Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome Rapid and sensitive detection of severe acute respiratory syndrome coronavirus by rolling circle amplification Early diagnosis of SARS coronavirus infection by real time RT-PCR Genomic sequencing of a SARS coronavirus isolate that predated the Metropole Hotel case cluster in Hong Kong Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China Tracing SARS-coronavirus variant with large genomic deletion Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome Molecular epidemiology of SARS--from Amoy Gardens to Taiwan Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection Coronavirus genomic-sequence variations and the epidemiology of the severe acute respiratory syndrome SARS Transmission Pattern in Singapore Reassessed by Viral Sequence Variation Analysis Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers A biologically important single nucleotide polymorphism within the toll-like receptor-4 gene is not associated with rheumatoid arthritis Real-time PCR for simultaneous detection and genotyping of bovine viral diarrhea virus Detection and genotyping of varicella-zoster virus by Taq-Man allelic discrimination real-time PCR Detection and typing of Herpes Simplex virus (HSV) in mucocutaneous samples by TaqMan PCR targeting a gB segment homologous for HSV types 1 and 2 A recent study illustrated the use of mass spectrometry-based technology in characterizing SARS sequence variations [14] .
- keywords: acute; allelic; analysis; assays; clinical; coronavirus; cov; cuhk; deletion; detection; direct; discrimination; epidemic; genotypes; genotyping; isolates; nucleotide; patients; pcr; probes; rapid; respiratory; samples; sars; sequence; sequencing; severe; snvs; study; su10; syndrome; t c; t g; t nd; t t; variant; viral
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- cord-277010-2iecsho0
- author: Wen, Xiaohong
- title: Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study
- date: 2019-01-08
- words: 3101
- flesch: 43
- summary: Viral etiology of acute respiratory infection in Gansu Province Prevalence of respiratory viruses among children hospitalized from respiratory infections in Shenzhen, China Viral etiology of acute respiratory infections among children and associated meteorological factors in southern China Estimates of worldwide distribution of child deaths from acute respiratory infections Viral etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province Acute lower respiratory infections in developing countries Nucleic acid amplification-based diagnosis of respiratory virus infections Molecular diagnosis of respiratory viruses Currently, there are few available vaccines to prevent respiratory virus infections [5, 6] .
- keywords: acute; adults; age; aris; cases; children; china; clinical; detection; different; distribution; etiologies; flua; groups; huzhou; infections; influenza; older; outpatients; pcr; positive; predominant; previous; real; reports; respiratory; results; rhv; seasonal; specimens; studies; study; symptoms; time; tract; viral; viruses; years; young
- versions: original; plain text
- cord-278508-h145cxlp
- author: Streng, Andrea
- title: Continued high incidence of children with severe influenza A(H1N1)pdm09 admitted to paediatric intensive care units in Germany during the first three post-pandemic influenza seasons, 2010/11–2012/13
- date: 2015-12-18
- words: 4712
- flesch: 37
- summary: Furthermore, we described the clinical characteristics of influenza PICU patients and compared patients with severe A(H1N1)pdm09 disease between the post-pandemic seasons. The minimum incidence of influenza-associated PICU admissions per 100,000 children <17 years of age was calculated for each season based on the observed number of influenza PICU patients with a residential address in Bavaria.
- keywords: a(h1n1)pdm09; active; admissions; age; bacterial; bavaria; care; cases; characteristics; children; chronic; clinical; complications; conditions; data; days; disease; estimates; germany; group; high; higher; incidence; infection; influenza; intensive; median; observed; paediatric; pandemic; patients; pcr; period; picu; pneumonia; post; previous; proportion; respiratory; risk; screening; season; seasonal; severe; similar; studies; study; surveillance; table; total; treatment; underlying; vaccination; virus; years; younger
- versions: original; plain text
- cord-281916-v6u5mr2i
- author: Bonnin, Paul
- title: Study and interest of cellular load in respiratory samples for the optimization of molecular virological diagnosis in clinical practice
- date: 2016-08-09
- words: 4127
- flesch: 40
- summary: The underrecognized burden of influenza in young children Viral epidemiology and severity of respiratory infections in infants in 2009: a prospective study Techniques actuelles de diagnostic des infections virales respiratoires en réanimation Cost analysis of multiplex PCR testing for diagnosing respiratory virus infections Superiority of reverse-transcription polymerase chain reaction to conventional viral culture in the diagnosis of acute respiratory tract infections in children Increased detection of respiratory syncytial virus, influenza viruses, parainfluenza viruses, and adenoviruses with real-time PCR in samples from patients with respiratory symptoms Quantitation of respiratory syncytial virus RNA in nasal aspirates of children by real-time RT-PCR assay Molecular diagnosis of respiratory viruses Comparison of multiplex PCR assays and conventional techniques for the diagnostic of respiratory virus infections in children admitted to hospital with an acute respiratory illness Comparative evaluation of six commercialized multiplex PCR kits for the diagnosis of respiratory infections Identification of respiratory viruses in adults: nasopharyngeal versus sampling Development of an efficient qRT-PCR assay for quality control and cellular quantification of respiratory samples Guideline to reference gene selection for quantitative realtime PCR Comparison of flocked and rayon swabs for collection of respiratory epithelial cells from uninfected volunteers and symptomatic patients Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: the importance of sample integrity and quality control Swabbing for respiratory viral infections in older patients:a comparison of rayon and nylon flocked swabs Comparison among nasopharyngeal swab, nasal wash, and oropharyngeal swab for respiratory virus detection in adults with acute pharyngitis Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs Comparison of nasopharyngeal and oropharyngeal swabs for the diagnosis of eight respiratory viruses by real-time reverse transcription-PCR assays Evaluation of the Quidel QuickVue test for detection of influenza A and B viruses in the pediatric emergency medicine setting by use of three specimen collection methods A quantification of human cells using an ERV-3 real time PCR assay Not applicable. key: cord-281916-v6u5mr2i authors: Bonnin, Paul; Miszczak, Fabien; Kin, Nathalie; Resa, Cecile; Dina, Julia; Gouarin, Stephanie; Viron, Florent; Morello, Remy; Vabret, Astrid title: Study and interest of cellular load in respiratory samples for the optimization of molecular virological diagnosis in clinical practice date: 2016-08-09 journal: BMC Infect Dis DOI: 10.1186/s12879-016-1730-9 sha: doc_id: 281916 cord_uid: v6u5mr2i BACKGROUND: Respiratory viral diagnosis of upper respiratory tract infections has largely developed through multiplex molecular techniques.
- keywords: acute; adults; age; analysis; aspirates; average; cells; cellularity; children; clinical; comparison; curve; detection; diagnosis; group; human; infections; load; log; molecular; multiplex; nasal; nasopharyngeal; negative; number; pcr; positive; possible; quality; quantification; reaction; real; respiratory; results; samples; sampling; specimens; study; swabs; targets; techniques; threshold; time; upper; variables; viral; viral detection; virological; viruses
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- cord-282533-w6kl74c8
- author: Li, Jin
- title: Rapid detection of respiratory organisms with the FilmArray respiratory panel in a large children’s hospital in China
- date: 2018-10-11
- words: 3389
- flesch: 39
- summary: Epidemiology of viral respiratory infections Community-acquired pneumonia requiring hospitalization among U.S. children Epidemiology of acute respiratory infections in children in Guangzhou: a three-year study Seroprevalence of pertussis in China: need to improve vaccination strategies The seroepidemiology of immunoglobulin G antibodies against pertussis toxin in China: a cross sectional study Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label, randomised controlled trial Multiplex PCR and emerging technologies for the detection of respiratory pathogens an automated nested multiplex PCR system for multi-pathogen detection: development and application to respiratory tract infection Charnot-Katsikas A. Comparison of Cepheid Xpert flu/RSV XC and BioFire FilmArray for detection of influenza a, influenza B, and respiratory syncytial virus Comparison of the FilmArray assay and in-house real-time PCR for detection of respiratory infection Comparison of FilmArray respiratory panel and laboratory-developed real-time reverse transcriptionpolymerase chain reaction assays for respiratory virus detection Comparison of the FilmArray respiratory panel and Prodesse real-time PCR assays for detection of respiratory pathogens FilmArray(R) respiratory panel performance in respiratory samples from neonatal care units Seasonality and prevalence of respiratory pathogens detected by multiplex PCR at a tertiary care medical center Human metapneumovirus subgroup changes and seasonality during epidemics Seasonality, incidence, and repeat human metapneumovirus lower respiratory tract infections in an area with a high prevalence of human immunodeficiency virus type-1 infection Etiologic spectrum and occurrence of coinfections in children hospitalized with community-acquired pneumonia Performance of a novel microarray multiplex PCR for the detection of 23 respiratory pathogens (SYMP-ARI study) In the present study, patients suspected of having pertussis were diagnosed with pertussis when B. pertussis was positive by FilmArray RP detection and were otherwise diagnosed with pertussis-like syndrome.
- keywords: adv; age; assay; atypical; children; china; clinical; common; data; detection; diagnosis; different; entero; filmarray; groups; high; highest; human; infections; influenza; methods; multiplex; organisms; panel; para; pathogens; patients; pcr; pediatric; pertussis; pneumoniae; positive; prevalence; rate; respiratory; results; rhino; rsv; rtis; samples; specimens; sputum; study; table; time; tract; viruses; year
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- cord-282898-hsqvkm2i
- author: Matsuda, Kentaro
- title: Gene and cytokine profile analysis of macrolide-resistant Mycoplasma pneumoniae infection in Fukuoka, Japan
- date: 2013-12-16
- words: 3783
- flesch: 40
- summary: In the present study, we have clarified 89.2% of pediatric M. pneumoniae infections were caused by either of two macrolide-resistant genotypes of M. pneumoniae. This study assessed the present status of M. pneumoniae infection in Japan and clinical end-points to distinguish children with MR-M. pneumoniae.
- keywords: 23s; a2063; a2063 t; agents; analysis; antibiotics; antimicrobial; azm; children; clinical; cytokines; data; development; domain; findings; fukuoka; gene; genotypes; infection; japan; levels; macrolide; mics; mutation; mycoplasma; number; patients; pcr; pediatric; pneumoniae; present; resistant; rrna; serum; significant; strains; study; susceptibility; table; time; total; transition; transversion
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- cord-283190-fc05u8mx
- author: Neupane, Dinesh
- title: Knowledge, attitudes and practices related to avian influenza among poultry workers in Nepal: a cross sectional study
- date: 2012-03-30
- words: 4409
- flesch: 45
- summary: IF: Knowledge, attitudes and practices of avian influenza poultry workers World Health Organisation: key: cord-283190-fc05u8mx authors: Neupane, Dinesh; Khanal, Vishnu; Ghimire, Kamal; Aro, Arja R; Leppin, Anja title: Knowledge, attitudes and practices related to avian influenza among poultry workers in Nepal: a cross sectional study date: 2012-03-30 journal: BMC Infect Dis DOI: 10.1186/1471-2334-12-76 sha: doc_id: 283190 cord_uid: fc05u8mx BACKGROUND: Avian influenza is a considerable threat to global public health.
- keywords: afraid; age; attitudes; avian; behaviours; boots; cases; control; cross; disinfecting; district; education; equipment; face; factors; farms; fear; findings; government; hand; health; high; higher; human; influenza; information; knowledge; level; low; majority; mass; measures; media; nepal; newspapers; number; outbreak; owners; pandemic; personal; poultry; practices; preventive; protective; respondents; response; risk; role; scale; studies; study; use; washing; workers
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- cord-283450-w6scpc65
- author: Amariei, Raluca
- title: The United States and Canada as a coupled epidemiological system: An example from hepatitis A
- date: 2008-02-28
- words: 6691
- flesch: 49
- summary: Adjusted incidence in the US and Canada after a sudden increase in US incidence Figure 6 Adjusted incidence in the US and Canada after a sudden increase in US incidence. For instance, if Canadian incidence were 5 per 100,000 per year, and US incidence changed from 10 per 100,000 per year to 15 per 100,00 per year (due to more foodborne outbreaks in that country, for example), then the additional risk of infection per year that Canadian residents assume upon themselves due to travel to the US would double.
- keywords: adjusted; age; age class; annual; attributable; average; canada; canadian; canadian incidence; cases; children; class; classes; countries; country; coverage; data; disease; effects; endemic; endemic countries; equations; figure; hepatitis; higher; immunity; incidence; individuals; infected; infection; model; number; outbreaks; parameters; person; rate; reported; reporting; residents; resp; results; risk; states; subclinical; time; transmission; travel; united; universal; universal vaccination; vaccination; vaccine; values; volume; year
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- cord-284393-s9qp9a4e
- author: Wei, Yiping
- title: Clinical characteristics of 276 hospitalized patients with coronavirus disease 2019 in Zengdu District, Hubei Province: a single-center descriptive study
- date: 2020-07-29
- words: 4272
- flesch: 48
- summary: In terms of laboratory tests, 75% of patients had lymphopenia, and more obvious findings were noted in severe patients. [14] showed that the age of severe patients was significantly older than that of non-severe patients.
- keywords: admission; areas; cases; characteristics; china; clinical; comorbidities; coronavirus; covid-19; criteria; critical; data; date; days; disease; epidemic; exposure; features; fever; findings; group; hospital; important; infection; laboratory; length; median; medical; mild; non; novel; older; outbreak; outcomes; patients; pneumonia; province; resources; respiratory; results; risk; sars; severe; severe patients; severity; stay; study; symptoms; time; treatment; understanding; wuhan; years; zengdu
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- cord-285976-l7voruz7
- author: Tewara, Marlvin Anemey
- title: Small-area spatial statistical analysis of malaria clusters and hotspots in Cameroon;2000–2015
- date: 2018-12-07
- words: 5050
- flesch: 39
- summary: Our objectives are to; i) use the spatial autocorrelation technique to analyze malaria spatial patterns in ArcGIS for desktop, ii) map the distribution of malaria cluster points, iii) identify urban-rural clusters with statistically significant hotspots of the disease, and iv) identify environmental factors associated with the distribution of malaria cases. Malaria risk maps and the applications of spatial malaria epidemiology in the fight against malaria in Africa has been limited.
- keywords: administrative; africa; analysis; arcgis; areas; associated; association; authors; autocorrelation; cameroon; cases; clusters; control; data; density; dhs; disease; distribution; douala; environmental; factors; falciparum; fig; geographic; global; health; high; hotspots; infectious; international; itns; locations; low; lower; malaria; malaria cases; mapping; maps; methods; moran; north; pattern; plasmodium; points; population; prevalence; prevention; programs; public; rainfall; regional; regions; risk; rural; rural areas; scale; significant; small; smaller; south; spatial; statistical; study; surveillance; survey; technique; transmission; urban; use; vegetation; west; year
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- cord-286843-8qh1pblc
- author: Quah, Jessica
- title: Impact of microbial Aetiology on mortality in severe community-acquired pneumonia
- date: 2018-09-04
- words: 4065
- flesch: 34
- summary: The immunology of influenza virusassociated bacterial pneumonia Integrated clinical, pathologic, Virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque Kinetics of coinfection with influenza a virus and Streptococcus pneumoniae Etiology of severe communityacquired pneumonia during the 2013 hajj-part of the MERS-CoV surveillance program Clinical and molecular characterization of rhinoviruses a, B, and C in adult patients with pneumonia Human rhinoviruses and severe respiratory infections: is it possible to identify at-risk patients early? viral pneumonia and acute respiratory distress syndrome Burden of acute respiratory disease of epidemic and pandemic potential in the WHO eastern Mediterranean region: a literature review Global threat of animal influenza viruses of zoonotic concern: then and now Surviving Sepsis campaign: international guidelines for Management of Severe Sepsis and Septic Shock Global and local epidemiology of communityacquired pneumonia: the experience of the CAPNETZ network Global changes in the epidemiology of community-acquired pneumonia Community-acquired pneumonia requiring hospitalization among U.S Adults Comprehensive molecular testing for respiratory pathogens in community-acquired pneumonia Empirical use of fluoroquinolones improves the survival of critically ill patients with tuberculosis mimicking severe pneumonia Impact of antibiotic therapy in severe community-acquired pneumonia: data from the Infauci study Predictive factors of mortality in severe community-acquired pneumonia: a model with data on the first 24h of ICU admission Viral infection in patients with severe pneumonia requiring intensive care unit admission Etiology of severe pneumonia in the very elderly Assessment of prognosis in patients with community-acquired pneumonia who require mechanical ventilation The authors would like to thank the following: Ms. Carmen Kam, the resident biostatistician for verification of the study statistical analysis; nurses Ms. Wang Xi Qin, Ms. Goh Yuan Xuan, Ms. Lim Qian Ru for assistance in data collection; senior medical technologist Ms. Heng Ying Xuan, Ms. Lee Hui Zi for assistance in performance of PCR tests; Dr. Tay Tunn Ren for her tutelage in manuscript writing. Polymerase chain reaction Etiology and outcome of severe community acquired pneumonia in immunocompetent adults Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway Epidemiology of community-acquired respiratory tract infections in adults The intensive care global study on severe acute respiratory infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia Molecular diagnosis of respiratory viruses The FilmArray® respiratory panel: an automated, broadly multiplexed molecular test for the rapid and accurate detection of respiratory pathogens Rapid viral diagnosis for acute febrile respiratory illness in children in the emergency department Clinical utility of on-demand multiplex respiratory pathogen testing among adult outpatients Burden of respiratory viruses in patients with acute respiratory failure Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis Clinical characteristics and outcomes in hospitalized patients with respiratory viral co-infection during the 2009 H1N1 influenza pandemic Management of severe communityacquired pneumonia: a survey on the attitudes of 468 physicians in Iberia and South America Clinical practice of respiratory virus diagnostics in critically ill patients with a suspected pneumonia: a prospective observational study Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the Management of Community-Acquired Pneumonia in adults Acute management and long-term survival among subjects with severe Middle East respiratory syndrome coronavirus pneumonia and ARDS Virus-induced acute respiratory distress syndrome: epidemiology, management and outcome Influenza a (H1N1) vs non-H1N1 ARDS: analysis of clinical course A prospective one-year microbiologic survey of combined pneumonia and respiratory failure The use of polymerase chain reaction amplification for the detection of viruses and Bacteria in severe communityacquired pneumonia
- keywords: acute; admission; aetiologies; aetiology; analysis; apache; authors; bacterial; bacterial co; blood; cap; care; clinical; common; community; cultures; data; detection; diagnostic; epidemiology; hospital; impact; infections; influenza; intensive; isolated; medical; microbial; microbiological; mixed; molecular; mortality; pathogens; patients; pcr; pneumonia; potential; present; primary; pulmonary; ratio; regression; respiratory; risk; score; serum; severe; severe cap; severity; streptococcus; study; table; testing; tests; time; tuberculosis; variables; viral; viruses
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- cord-287367-1sdt9zz8
- author: Andrews, Denise
- title: Multiplex PCR point of care testing versus routine, laboratory-based testing in the treatment of adults with respiratory tract infections: a quasi-randomised study assessing impact on length of stay and antimicrobial use
- date: 2017-10-10
- words: 6431
- flesch: 45
- summary: 20% of control arm patients and 24% of intervention arm patients had an RP detected. FilmArray® POC testing occurred on even days of the month (intervention) or routine, laboratory-based RP PCR testing +/− atypical serology on odd days (control).
- keywords: admission; analysis; antibiotics; antimicrobial; antivirals; arm; arms; available; beta; care; cases; clinical; community; control; control arm; data; days; decision; delay; detection; diagnostic; discharge; evidence; faster; filmarray; hospital; impact; infection; influenza; intervention; intervention arm; laboratory; lactam; length; lower; multiplex; mycoplasma; negative; outcomes; panel; pathogen; patients; pcr; pneumonia; poc; poc testing; positive; prescribing; primary; randomised; rapid; respiratory; results; rna; routine; rti; score; secondary; staff; stay; study; tat; testing; tests; time; tract; treatment; trial; use; viral; virus; viruses; ward
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- cord-287546-0x294f8t
- author: Lin, Feng
- title: An optimal control theory approach to non-pharmaceutical interventions
- date: 2010-02-19
- words: 7124
- flesch: 50
- summary: [40] developed optimal control policies for immunization assuming an infinite pandemic terminal time. We also computed control policies for systems assuming quadratic control cost instead of linear cost, i.e., the value function is written as , while the system dynamics still follow Eq.
- keywords: analysis; available; bang; cases; community; control; cost; cumulative; days; death; disease; effective; epidemic; expected; exponential; figure; function; health; impact; implementation; infected; infectious; influenza; input; interventions; level; linear; maximum; model; npi; npi implementation; npis; number; optimal; optimal control; outbreak; overall; pandemic; parameters; people; person; policies; policy; population; quadratic; rate; recovery; sensitivity; spread; state; strength; structure; study; susceptible; system; table; terminal; time; transmission; uncertainty; vaccine; value; virus
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- cord-287931-cxqzac4a
- author: Huang, Weiwei
- title: An easy operating pathogen microarray (EOPM) platform for rapid screening of vertebrate pathogens
- date: 2013-09-20
- words: 5170
- flesch: 42
- summary: The predominant techniques for identification of microbial pathogens depend on conventional clinical microbiology monitoring approaches. Since the first application of a high-throughput, rapid, and unbiased microarray for detecting viral pathogens in 2002
- keywords: 18s; acid; adenovirus; amplification; analysis; approaches; bacteria; china; clinical; control; data; database; detection; diagnostic; disease; dna; enrichment; enterovirus; eopm; ev71; families; fungi; genera; genus; hfmd; high; human; identification; infectious; influenza; known; level; methods; microarray; microbes; microbial; normal; novel; nucleic; number; oligonucleotide; outbreaks; parasites; pathogens; patients; pcr; platform; positive; probes; random; rapid; related; responsible; results; rna; rrna; samples; screening; sensitivity; sequences; serum; similar; software; species; specific; surveillance; symptoms; system; target; user; vertebrate; viral; virus; viruses
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- cord-288372-48wao8a0
- author: Dia, Ndongo
- title: Respiratory viruses associated with patients older than 50 years presenting with ILI in Senegal, 2009 to 2011
- date: 2014-04-08
- words: 3874
- flesch: 50
- summary: The impact of influenza on the health and health care utilisation of elderly people Influenza-related hospitalisation and death in Australians aged 50 years and older New respiratory viruses and the elderly Mortality associated with influenza and respiratory syncytial virus in the United States Surveillance of 16 respiratory viruses in patients with influenza-like illness in Nanjing Current research on influenza and other respiratory viruses: II international symposium Aetiology of influenza-like illness in adults includes parainfluenzavirus type 4 Acute viral infections of upper respiratory tract in elderly people living in the community: comparative, prospective, population based study of disease burden Influenza A/H1N1 2009 pandemic and respiratory virus infections The post-infection outcomes of influenza and acute respiratory infection in patients above 50 years of age in Japan: an observational study Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness Epidemiology of 2009 pandemic influenza a (H1N1) deaths in the United States Outbreaks of 2009 pandemic influenza A (H1N1) among long-term-care facility residents-three states Nationwide surveillance of 18 respiratory viruses in patients with influenza-like illnesses: a pilot feasibility study in the French Sentinel network Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults Fields Virology Viral respiratory infections in elderly patients and patients with chronic obstructive pulmonary disease A subregional analysis of epidemiologic and genetic characteristics of influenza A(H1N1)pdm09 in Africa Respiratory viruses in children admitted to hospital intensive care units: evaluating the CLART1 150 viruses were detected: influenza viruses (44.7%) and rhinoviruses (26.7%) were the most prevalent.
- keywords: adults; age; associated; authors; cases; clinical; detection; diversity; elderly; group; high; human; ili; illness; infections; influenza; kit; like; number; old; older; pandemic; patients; pcr; peak; people; period; pharyngeal; positive; present; prevalence; previous; respiratory; respiratory viruses; results; rhinoviruses; rna; rsv; samples; senegal; sentinel; studies; study; surveillance; symptoms; syncytial; viral; viruses; years
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- cord-288720-bd86zswo
- author: Lin, Sheng
- title: Epidemiological and clinical characteristics of 161 discharged cases with coronavirus disease 2019 in Shanghai, China
- date: 2020-10-20
- words: 3318
- flesch: 48
- summary: As far as we know, this research includes the largest discharged COVID-19 case series and report an initial evaluation of the epidemiological characteristics, clinical characteristics, laboratory results, and disease course of COVID-19 cases. We aimed to further describe the epidemiological and clinical characteristics of discharged COVID-19 cases and evaluate the public health interventions.
- keywords: admission; age; cases; characteristics; china; clinical; confirmation; coronavirus; covid-19; days; discharge; disease; duration; emergency; epidemic; epidemiological; fever; health; hospitalization; illness; january; level; median; medical; moderate; ncov; novel; onset; patients; pneumonia; public; public health; respiratory; response; shanghai; study; symptoms; time; transmission; visit; wuhan
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- cord-288972-dc6xbxha
- author: Cowling, Benjamin J
- title: Entry screening to delay local transmission of 2009 pandemic influenza A (H1N1)
- date: 2010-03-30
- words: 2253
- flesch: 41
- summary: To determine the date of first imported case and first local case the search queries were extended accordingly. Table 1 shows the intervals between confirmations of first imported cases and first local cases, categorized by entry screening tools.
- keywords: additional; authors; cases; confirmation; confirmed; countries; data; dates; day; delays; entry; h1n1; health; influenza; laboratory; local; measures; modeling; nations; official; organization; pandemic; resources; results; screening; spread; study; time; tools; transmission; travelers; virus; world
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- cord-290432-4dli5emd
- author: O’Grady, Kerry-Ann F.
- title: Upper airway viruses and bacteria in urban Aboriginal and Torres Strait Islander children in Brisbane, Australia: a cross-sectional study
- date: 2017-04-04
- words: 3768
- flesch: 40
- summary: A population-based cohort study Diverging trends for lower respiratory infections in non-aboriginal and aboriginal children Lower respiratory infections in Australian indigenous children Estimates of aboriginal and Torres Strait Islander Australians General practice activity in Australia Upper airway viruses and bacteria detection in clinical pneumonia in a population with high nasal colonisation do not relate to clinical signs Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: a nested case-control study of the Drakenstein child health study The respiratory health of urban indigenous children aged less than 5 years: study protocol for a prospective cohort study Successful application of a simple specimen transport method for the conduct of respiratory virus surveillance in remote indigenous communities in Australia Mailed versus frozen transport of nasal swabs for surveillance of respiratory bacteria in remote indigenous communities in Australia Prevalence, codetection and seasonal distribution of upper airway viruses and bacteria in children with acute respiratory illnesses with cough as a symptom Upper airway viruses and bacteria and clinical outcomes in children with cough Hospitalisation of indigenous children in the northern Territory for lower respiratory illness in the first year of life General health, otitis media, nasopharyngeal carriage and middle ear microbiology in northern Territory aboriginal children vaccinated during consecutive periods of 10-valent or 13-valent pneumococcal conjugate vaccines The interaction between respiratory viruses and pathogenic bacteria in the upper respiratory tract of asymptomatic aboriginal and non-aboriginal children Single-and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen Role of nasopharyngeal bacteria and respiratory viruses in acute symptoms of young children Respiratory virus detection and clinical diagnosis in children attending day care Viral respiratory infections in hospitalized and community control children in Alaska Aetiological role of common respiratory viruses in acute lower respiratory infections in children under five years: a systematic review and meta-analysis Australian Institute of Health & Welfare. Indigenous children are 2.6 times more likely to present to emergency departments (ED) with ARI
- keywords: aboriginal; acute; aged; airway; analyses; ariwc; asymptomatic; australia; bacteria; care; children; clinical; cohort; common; community; cough; data; detection; differences; enrolment; health; high; human; indigenous; infections; islander; lower; months; nasal; non; organisms; pcr; pneumoniae; population; positive; prevalence; primary; remote; research; respiratory; strait; studies; study; swabs; time; torres; upper; urban; viruses; years
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- cord-291393-iht5zndl
- author: De Angelis, Giulia
- title: Confirmed or unconfirmed cases of 2019 novel coronavirus pneumonia in Italian patients: a retrospective analysis of clinical features
- date: 2020-10-19
- words: 2722
- flesch: 42
- summary: Additionally, the proportion of ARDS in the group of COVID-19 confirmed patients was significantly higher than in the group of COVID-19 unconfirmed patients. We tested the hypothesis that negative patients did not differ from SARS-CoV-2 RNA positive patients by comparing features of 165 cases with clinically diagnosed 2019-nCoV pneumonia in our hospital.
- keywords: acute; analysis; ards; cases; clinical; confirmed; coronavirus; cov-2; covid-19; days; diagnosis; disease; features; higher; hospital; imaging; infection; iqr; laboratory; levels; median; multivariable; ncov; ncov pneumonia; negative; novel; patients; pcr; pneumonia; positive; respiratory; results; samples; sars; severe; study; swab; symptoms; syndrome; testing; value
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- cord-292609-e99y0l5a
- author: Liu, Ye
- title: Ferret badger rabies origin and its revisited importance as potential source of rabies transmission in Southeast China
- date: 2010-08-06
- words: 3556
- flesch: 49
- summary: The eventual role of FB rabies in public health remains unclear. In conclusion, we demonstrated that FB rabies is likely occurring as an independent enzootic that became established in the FB populations from a dog RV variant distributed in southeast/south China.
- keywords: anhui; animal; antibody; areas; badger; bites; brain; cases; china; chinese; collected; data; diagnosis; dog; dogs; epidemiological; exposure; fat; fbs; ferret; fluorescent; group; health; high; human; hunters; isolates; jiangxi; laboratory; mice; pep; percentage; phylogenetic; populations; positive; potential; provinces; rabies; regions; related; rvs; samples; seroconversion; serum; southeast; study; test; transmission; vaccination; virus; vna; zhejiang
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- cord-292828-29jbf9ik
- author: Alsaleh, Asma N
- title: Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: the importance of sample integrity and quality control
- date: 2014-01-09
- words: 3920
- flesch: 39
- summary: Such studies do however have some logistical challenges, particularly concerning respiratory sample collection and transport. The EHV1 component was performed as an extraction and inhibitor control as described previously [24] , while ERV3 was used as a marker to evaluate the quality of nasal swab sample collection [25] .
- keywords: anterior; assays; australia; birth; brisbane; chain; children; cohort; collection; community; control; detection; dna; ehv1; erv3; extraction; extracts; figure; following; fungal; hospital; human; impact; infants; infections; laboratory; levels; load; longitudinal; mould; nasal; negative; observed; orchid; parents; pcr; polymerase; positive; presence; quality; rates; reaction; real; research; respiratory; respiratory virus; reverse; samples; sec; specimens; studies; study; swab; testing; time; transport; viral; virus; virus detection; viruses; visible
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- cord-293858-dk4snw9r
- author: Yang, Lin
- title: Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination
- date: 2019-02-14
- words: 4084
- flesch: 42
- summary: Emerging infections: pandemic influenza Influenza vaccines Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review Vaccines for preventing influenza in healthy adults Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review Vaccines for preventing influenza in the elderly Effectiveness of influenza vaccine in the community-dwelling elderly Mortality benefits of influenza vaccination in elderly people: an ongoing controversy Impact of influenza vaccination on seasonal mortality in the US elderly population The effect of universal influenza immunization on mortality and health care use Immune response to influenza vaccination in community-dwelling Chinese elderly persons Preliminary findings of a randomized trial of non-pharmaceutical interventions to prevent influenza transmission in households Seasonal influenza vaccination coverage survey for the 2012/13 season Australian Institute of Health and Welfare International Monetary Fund: World economic outlook Database Model selection in time series studies of influenza-associated mortality Modern Epidemiology Influenza vaccination in 2000: recommendations and vaccine use in 50 developed and rapidly developing countries Antibody response to influenza vaccination in the elderly: a quantitative review Cochrane re-arranged: support for policies to vaccinate elderly people against influenza Excess mortality associated with influenza a and B virus in Hong Kong Excess mortality associated with the 2009 pandemic of influenza a(H1N1) in Hong Kong Age and sex differences in rates of influenza-associated hospitalizations in Hong Kong Dietary habits and the short-term effects of air pollution on mortality in the Chinese population in Hong Kong Influenza-associated hospitalization in a subtropical city Taken together, available evidence suggests that there is a need to assess the effect of influenza vaccination at the population level, especially for those aged ≥65 years.
- keywords: additional; aged; annual; appendix; brisbane; burden; cause; coverage; data; disease; effectiveness; elderly; estimates; excess; file; health; hong; hong kong; hospitalizations; ihd; increase; influenza; kong; level; mortality; older; pandemic; people; percentage; period; pneumococcal; population; post; pre; rates; relative; sars; sars period; seasonal; specific; stroke; studies; study; vaccination; vaccine; years
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- cord-294062-3esrg1jw
- author: Tam, Clarence C.
- title: Association between semi-quantitative microbial load and respiratory symptoms among Thai military recruits: a prospective cohort study
- date: 2018-09-14
- words: 4514
- flesch: 33
- summary: Viruses were detected in 13.8% (43/312) and bacteria in 93.3% (291/312) of non-acute samples. Hi-nonB, rhinovirus, and coronavirus 229 were detected significantly less frequently in non-acute samples collected at the start of the training period than acute samples (p-values < 0.05) ( Table 1) .
- keywords: acute; acute samples; agents; army; association; asymptomatic; bacterial; baseline; chain; children; clinical; collected; correlation; data; detection; diagnostic; end; follow; high; higher; human; illness; individuals; infection; influenza; load; lower; microbe; microbial; military; multiplex; nasal; non; organisms; participants; pathogens; patients; pcr; period; pneumoniae; population; quantitative; real; recruits; respiratory; rhinovirus; samples; semi; setting; specific; specimens; start; study; swab; symptoms; table; thai; throat; time; tract; training; type; value; viral; viruses
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- cord-296375-gf0mgz5x
- author: Zhang, Xi
- title: Comparison of spatiotemporal characteristics of the COVID-19 and SARS outbreaks in mainland China
- date: 2020-10-30
- words: 3282
- flesch: 48
- summary: We found that COVID-19 cases were clustered mainly in Hubei, and other secondary clusters disappeared, except in Shandong. Therefore, in this study, by collecting the daily numbers of newly confirmed COVID-19 and SARS cases during the two epidemics, we aimed to determine the spatial behavior and temporal features of the COVID-19 spread in mainland China and compared them with respective features from the SARS epidemic using spatiotemporal analysis.
- keywords: analysis; april; areas; autocorrelation; beijing; cases; china; clustering; clusters; coronavirus; covid-19; daily; disease; february; health; high; hubei; incidence; infected; january; local; low; mainland; maximum; national; number; outbreak; patterns; people; period; provinces; risk; sars; scanning; secondary; significant; spatial; spatiotemporal; stage; study; time; transmission; window
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- cord-296868-fn4gzsw1
- author: Nishiura, Hiroshi
- title: Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan
- date: 2011-05-03
- words: 6648
- flesch: 36
- summary: In addition to the limited diagnostic performance of fever screening in identifying febrile influenza cases, it should be remembered that the readings of infrared thermoscanners are known to be influenced by other confounding factors, most notably by age and outdoor temperature [15, [20] [21] Although infrared thermoscanners are non-invasive and may detect a small portion of febrile influenza cases among the total passengers, our study has demonstrated fundamental problems in the reliance on fever in detecting and diagnosing influenza in international passengers.
- keywords: age; airport; arrival; auc; axillary; border; cases; datasets; diagnostic; early; entry; entry screening; febrile; fever; fever screening; figure; fraction; h1n1; health; hyperthermia; influenza; influenza cases; infrared; infrared thermoscanners; international; international airport; japan; levels; measure; medications; narita; non; npv; pandemic; passengers; performances; place; ppv; quarantine; reporting; sars; screening; self; sensitivity; small; specificity; stages; study; subjects; surface; temperature; terminal; thermoscanners; total; use; virus
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- cord-297024-90qq0xsw
- author: Kramer, Axel
- title: How long do nosocomial pathogens persist on inanimate surfaces? A systematic review
- date: 2006-08-16
- words: 3398
- flesch: 32
- summary: Zentralblatt für Bakteriologie und Hygiene, I Abt Orig B 1972 Persistence of Escherichia coli O157 on farm surfaces under different environmental conditions Influence of relative humidity and suspending menstrua on survival of Acineto Survival of enteric viruses on environmental fomites Persistence of Norwalk virus on environmental surfaces and its transfer to food Survival of influenza viruses an environmental surfaces Possible transmission by fomites of respiratory syncytial virus Survival on uncommon fomites of feline calicivirus, a surrogate of noroviruses Comparative efficacy of handwashing agents against cytomegalievirus The emerging nosocomial pathogens Cryptosporidium, Escherichia coli O157:h7, Helicobacter pylori, and hepatitis C: epidemiology, environmental survival, efficacy of disinfection, and control measures Survival of human enteric viruses in the environment and food Computer keyboards and faucet handles as reservoirs of nosocomial pathogens in the intensive care unit Survival of Acinetobacter baumannii on bed rails during an outbreak and during sporadic cases Environmental contamination due to methicillin-resistant Staphylococcus aureus: possible infection control implications The survival and transfer of microbial contamination via cloths, hands and utensils An experimental model for study of Candida survival and transmission in human volunteers Transmission of experimental rhinovirus infection by contaminated surfaces Survival of hepatitis A virus on human hands and its transfer on contact with animate an inanimate surfaces Prevention of surface-to-human transmission of rotaviruses by treatment with disinfectant spray Rotavirus survival on human hands and transfer of infectious virus to inanimate and nonporous inanimate surfaces Effects of cleaning and disinfection in reducing the spread of norovirus contamination via environmental surfaces Transmission of viruses via contact in a household setting: experiments using bacteriophage strain phiXI174 as a model virus Effect of fecal contamination on diarrheal illness rates in day-care centers Outbreak of Shigella sonnei in a clinical microbiology laboratory Outbreaks of infection with methicillin-resistant Staphylococcus aureus on neonatal and burns units of a new hospital Role of environmental cleaning in controlling an outbreak of Acinetobacter baumannii on a neurosurgical intensive care unit An outbreak of imipenem-resistant Acinetobacter baumannii in critically ill surgical patients Distribution of multi-resistant Gram-negative versus Gram-positive bacteria in the hospital inanimate environment A nosocomial outbreak of multiresistant Acinetobacter baumannii originating from an intensive care unit Control of nosocomial Clostridium difficile transmission in bone marrow transplant patients Prospective evaluation of environmental contamination by Clostridium difficile in isolation side rooms Acquisition of Clostridium difficile from the hospital environment A purpose built MRSA cohort study Outbreak of vancomycin-resistant enterococci in a burn unit Experience of vancomycin-resistant enterococci in a children's hospital Control of an outbreak of vancomycinresistant Enterococcus faecium in an oncology ward in South Africa: effective use of limited resources Management of an outbreak of vancomycin-resistant enterococci in the medical intensive care unit of a cancer center Role of environmental contamination as a risk factor for acquisition of vancomycin-resistant enterococci in patients treated in a medical intensive care unit Epidemiology of colonization of patients and environment with vancomycin-resistant enterococci Transfer of vancomycin-resistant enterococci via health care worker hands SARS in a hospital visitor and her intensivist SARS in hospital emergency room. key: cord-297024-90qq0xsw authors: Kramer, Axel; Schwebke, Ingeborg; Kampf, Günter title: How long do nosocomial pathogens persist on inanimate surfaces?
- keywords: acinetobacter; aeruginosa; aureus; bacteria; baumannii; candida; care; clostridium; coli; contaminated; contamination; control; data; days; difficile; disinfection; dry; enterococci; environmental; escherichia; evidence; experimental; fomites; gram; hand; hospital; human; humidity; hygiene; inanimate; infections; intensive; longer; months; mrsa; nosocomial; nosocomial pathogens; outbreak; pathogens; patients; persistence; pseudomonas; resistant; spp; staphylococcus; studies; study; surfaces; survival; susceptible; transmission; type; und; unit; vancomycin; viruses
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- cord-297029-b38sm4y9
- author: Murillo-Zamora, Efrén
- title: Male gender and kidney illness are associated with an increased risk of severe laboratory-confirmed coronavirus disease
- date: 2020-09-16
- words: 2958
- flesch: 45
- summary: In China, there was a higher frequency for severe patients to be current smokers (16.9% vs. 11.8%), however, no association analysis was performed [23] . In multiple analysis, male gender (RR = 1.13, 95% CI 1.06–1.20), advanced age ([reference: 15–29 years old] 30–44, RR = 1.02, 95% CI 0.94–1.11; 45–59, RR = 1.26, 95% CI 1.15–1.38; 60 years or older, RR = 1.44, 95% CI 1.29–1.60), chronic kidney disease (RR = 1.31, 95% CI 1.04–1.64) and thoracic pain (RR = 1.16, 95% CI 1.10–1.24) were associated with an increased risk of severe disease.
- keywords: acute; admission; age; analysis; cases; characteristics; chronic; clinical; coronavirus; covid-19; data; disease; dyspnea; factors; gender; healthcare; higher; hospital; illness; imss; infection; kidney; laboratory; male; medical; mexico; multiple; non; old; patients; respiratory; risk; sample; sars; severe; severity; study; subjects; surveillance; symptoms; system; viral; years
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- cord-297494-6yxmaihl
- author: Katsurada, Naoko
- title: The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study
- date: 2017-12-06
- words: 4343
- flesch: 37
- summary: This multicentre prospective study enrolled pneumonia patients aged ≥15 years from September 2011 to August 2014. Studies have shown that viral infection is common in pneumonia patients
- keywords: adults; age; arr; aspiration; bacterial; chronic; clinical; community; comorbidities; comorbidity; disease; effects; factors; groups; higher; hospital; hrv; infection; influenza; japan; lower; medicine; mortality; multiple; nagasaki; paramyxovirus; pathogens; patients; pcr; pneumonia; positive; prospective; respiratory; review; risk; rsv; samples; sputum; status; studies; study; symptoms; systematic; table; type; viral; viruses; years
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- cord-298002-jvnwivrg
- author: Wang, Jian
- title: COVID-19 confirmed patients with negative antibodies results
- date: 2020-09-22
- words: 1505
- flesch: 55
- summary: In summary, this work presents two typical cases of COVID-19 patients without producing IgM/ IgG and comprehensively characterizes their initial symptoms, chest CT results, medication, and laboratory test results, hoping to draw more attentions to this type of patients. From January 30 to March 15, 310 of COVID-19 patients who were positive for SARS-CoV-2 real time reverse-transcription PCR (RT-PCR) testing and received IgM and IgG detection at Wuhan Union Hospital (Wuhan, China) were enrolled.
- keywords: antibodies; china; cov-2; covid-19; days; february; igg; igm; laboratory; march; negative; onset; patients; pcr; pneumonia; positive; results; sars; symptoms; table; test; wuhan
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- cord-298899-lkrmg5qr
- author: Xie, Yewei
- title: Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis
- date: 2020-08-31
- words: 6251
- flesch: 50
- summary: Download today's data on geographic distribution of COVID-19 cases worldwide Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study Ethnicity and COVID-19: an urgent public health research priority COVID-19 sex-disaggregated data tracker-Sex, gender and COVID-19 Clinical features and outcomes of 98 patients hospitalized with SARS-CoV-2 infection in Daegu, South Korea: a brief descriptive study Early epidemiological and clinical manifestations of COVID-19 in Japan Clinical, radiological and therapeutic characteristics of patients with COVID-19 in Saudi Arabia Clinical course and potential predicting factors of pneumonia of adult patients with coronavirus disease 2019 (COVID-19): a retrospective observational analysis of 193 confirmed cases in Thailand Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO clinical characterization protocol: prospective observational cohort study Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 network Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia Clinical and epidemiological characteristics of patients diagnosed with COVID-19 in a tertiary care center in Mexico CITY: a prospective cohort study Early experience with COVID-19 patients at academic hospital in southwestern United States Clinical characteristics and morbidity associated with coronavirus disease 2019 in a series of patients in metropolitan Detroit Clinical characteristics of Covid-19 in New York city Epidemiological and clinical characteristics of the early phase of the COVID-19 epidemic in Brazil Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study Utility of hyposmia and hypogeusia for the diagnosis of COVID-19 Selfreported olfactory and taste disorders in patients with severe acute respiratory coronavirus 2 infection: a cross-sectional study COVID-19 anosmia reporting tool: initial findings Features of anosmia in COVID-19 Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Smell dysfunction: a biomarker for COVID-19. In the US for example, the reasons that turned hospitals into infection hotspots included the overload of COVID-19 patients and inappropriate management against the pandemic in hospitals [29] .
- keywords: acute; additional; analysis; asymptomatic; cases; cfr; characteristics; china; clinical; closed; common; community; conditions; control; coronavirus; countries; country; course; cov-2; covid-19; data; days; death; disease; early; epidemic; epidemiological; exposure; factors; features; file; findings; health; higher; hospital; household; hsm; icu; incubation; infected; infection; italy; july; korea; male; march; medical; meta; mortality; multiple; ncov; novel; novel coronavirus; number; outbreak; outcomes; pandemic; patients; pcr; people; period; pneumonia; population; potential; prevention; proportion; rate; records; research; results; retrospective; review; risk; sars; severe; south; spread; stage; states; studies; study; super; symptoms; time; transmission; united; workers; wuhan; years
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- cord-299750-zkrlm3ds
- author: Cui, Wei
- title: Factors associated with death in hospitalized pneumonia patients with 2009 H1N1 influenza in Shenyang, China
- date: 2010-05-31
- words: 4967
- flesch: 47
- summary: Persons aged 50 years or older showed a low incidence of 2009 H1N1 influenza infection, this may be due to protection by preexisting immunity resulting from previous exposure to H1N1 influenza infection, along with reduced outdoor activity by these individuals because of the fear of H1N1 infection. In our study, almost 80% of the hospitalizations due to H1N1 influenza infection involved individuals who were between the ages of 18 and 49 years.
- keywords: admission; analysis; antiviral; blood; bmi; cases; cd4; cell; china; chronic; clinical; condition; counts; crp; cultures; data; days; death; disease; factors; h1n1; h1n1 influenza; heart; hospital; icu; illness; index; infection; influenza; initiation; laboratory; ldh; lymphopenia; median; medical; obesity; onset; oseltamivir; outcomes; pandemic; patients; pneumonia; range; respiratory; results; risk; severe; shenyang; study; table; test; therapy; time; treatment; underlying; virus; years
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- cord-300116-r93w4jm3
- author: Yi, Hana
- title: Profiling bacterial community in upper respiratory tracts
- date: 2014-11-13
- words: 5068
- flesch: 35
- summary: First, the age-related incidence of M. nonliquefaciens infection determined here is concordant with that of M. catarrhalis. Previously, M. catarrhalis was reported to be mostly associated with upper respiratory tract infections in children [50] , and its carriage rate was shown to be high in children (up to 75%) and extremely low in healthy adults (1%-3%)
- keywords: 16s; abundance; additional; adults; age; analysis; ani; average; bacterial; catarrhalis; children; clinical; communities; community; composition; data; distance; distinct; diversity; dna; figure; file; gene; genera; genome; group; haemophilus; healthy; hospital; human; immune; infection; influenza; microbial; microbiota; moraxella; neisseria; nonliquefaciens; oropharyngeal; pathogen; patients; people; profile; pyrosequencing; respiratory; respiratory tract; results; rrna; samples; species; specific; streptococcus; structure; study; subjects; table; tract; type; unifrac; upper; upper respiratory; viral; virulence; virus; viruses
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- cord-300230-a3jk6w90
- author: Ding, Ji-Guang
- title: Retrospective analysis of nosocomial infections in the intensive care unit of a tertiary hospital in China during 2003 and 2007
- date: 2009-07-25
- words: 3806
- flesch: 41
- summary: System Report, data summary from Nosocomial infections in medical-surgical intensive care units in Argentina: attributable mortality and length of stay Prevalence rate of nosocomial infection in a general hospital Surveillance of risk factors for nosocomial infection in patients in intensive care units Study on the changing trends in national nosocomial infection transaction investigation results Nosocomial infections in medical intensive care units in the United States Nosocomial infections: prospective survey of incidence in five French intensive care units Nosocomial infections in a neurosurgery intensive care unit Device-associated nosocomial infections in 55 intensive care units of 8 developing countries Epidemiology, risk factors and outcome of nosocomial infections in a Respiratory Intensive Care Unit in North India The excess length of stay was then calculated by subtracting the average length of stay for patients without nosocomial infection from that of patients with nosocomial infections.
- keywords: addition; antimicrobial; aureus; bsis; care; china; coli; common; countries; data; days; high; hospital; icu; infections; intensive; isolates; length; lower; lrtis; medical; nosocomial; nosocomial infections; overall; pathogens; patients; present; prevention; rate; resistant; respiratory; sites; states; stay; study; susceptibility; tract; united; units; utis; years
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- cord-301393-d1duepnb
- author: Wolfensberger, Aline
- title: Implementation and evaluation of a care bundle for prevention of non-ventilator-associated hospital-acquired pneumonia (nvHAP) – a mixed-methods study protocol for a hybrid type 2 effectiveness-implementation trial
- date: 2020-08-17
- words: 5973
- flesch: 28
- summary: To identify which factors in the implementation setting are associated with the actual degree of local implementation of the nvHAP bundle The study is conducted at the University Hospital Zurich (UHZ), Switzerland, a 950-bed tertiary-care teaching hospital covering all medical specialties except paediatrics and orthopaedics. On the hospital level the three periods are defined as follows: 1) hospital baseline period, before starting implementation in the first department; 2) hospital implementation period, from the beginning of the implementation period of the first department until end of implementation period of the last included department; 3) hospital intervention period following the hospital implementation period.
- keywords: action; additional; adherence; analysis; barriers; baseline; behaviour; bundle; care; case; change; collection; components; context; current; data; department; effectiveness; elements; evaluation; evidence; facilitators; factors; file; focus; following; formative; guidelines; healthcare; hospital; hybrid; implementation; incidence; indicators; infections; intervention; interviews; level; local; longitudinal; measures; medical; methods; mixed; model; non; nvhap; nvhap bundle; oral; outcomes; patients; period; plan; pneumonia; point; poisson; practice; prevention; process; qualitative; rates; research; results; specific; strategy; study; success; tdf; teams; time; university; use; vap; ventilator; zurich
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- cord-302393-hrz3bypr
- author: Omrani, Ali S.
- title: The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study
- date: 2020-10-19
- words: 4544
- flesch: 48
- summary: COVID-19 patients with significant co-morbidities or moderate to severe disease were hospitalized for inpatient management. This has stimulated discussions around rationing of critical care support for COVID-19 patients, including potentially difficult decisions to withdraw resources from one patient to provide them to another
- keywords: admission; age; analysis; bmi; cases; cause; characteristics; chronic; clinical; cohort; coronary; coronavirus; cov-2; covid-19; critical; data; days; deaths; diabetes; diagnosis; disease; factors; follow; healthcare; higher; hospitalization; hospitalized; hypertension; icu; individuals; infection; iqr; italy; kidney; logistic; majority; male; median; medical; morbidities; mortality; older; outcomes; patients; population; pregnant; qatar; regression; report; respiratory; risk; sars; severe; sex; study; supplementary; table; women; workers; years
- versions: original; plain text
- cord-302833-6kntd89t
- author: Radonovich, Lewis J.
- title: The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel
- date: 2016-06-02
- words: 5093
- flesch: 32
- summary: key: cord-302833-6kntd89t authors: Radonovich, Lewis J.; Bessesen, Mary T.; Cummings, Derek A.; Eagan, Aaron; Gaydos, Charlotte; Gibert, Cynthia; Gorse, Geoffrey J.; Nyquist, Ann-Christine; Reich, Nicholas G.; Rodrigues-Barradas, Maria; Savor-Price, Connie; Shaffer, Ronald E.; Simberkoff, Michael S.; Perl, Trish M. title: The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel date: 2016-06-02 journal: BMC Infect Dis DOI: 10.1186/s12879-016-1494-2 sha: doc_id: 302833 cord_uid: 6kntd89t BACKGROUND: Although N95 filtering facepiece respirators and medical masks are commonly used for protection against respiratory infections in healthcare settings, more clinical evidence is needed to understand the optimal settings and exposure circumstances for healthcare personnel to use these devices.
- keywords: acute; airborne; analysis; ari; attack; centers; clinical; cluster; comparison; complete; control; data; devices; disease; effectiveness; equipment; exposure; face; filter; filtering; fit; guidelines; hcp; hcps; healthcare; illness; incidence; infections; influenza; intervention; laboratory; levels; manuscript; masks; measures; medical; models; n95; number; occupational; outcome; participants; patients; pcr; period; personnel; prevention; primary; protection; randomized; rate; respect; respiratory; rpd; safety; sample; season; secondary; settings; site; spread; study; surgical; symptoms; transmission; trial; u.s; viral; virus; wear; wearer; workers; workplace; year
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- cord-303196-ltmu3ncu
- author: Pfitscher, L. C.
- title: Severe maternal morbidity due to respiratory disease and impact of 2009 H1N1 influenza A pandemic in Brazil: results from a national multicenter cross-sectional study
- date: 2016-05-21
- words: 4528
- flesch: 37
- summary: The study evaluated severe maternal morbidity cases, from a prospective surveillance, according to the 2009 WHO newly publicized criteria for these conditions [6] . We only have data on severe maternal morbidity cases, comparing less severe (PLTC) to more severe cases (SMO).
- keywords: a(h1n1)pdm09; acute; analysis; brazil; care; cases; clinical; complications; conditions; considered; data; death; delay; diagnosis; disease; edema; factors; failure; group; h1n1; health; hospitals; infection; influenza; management; maternal; maternal morbidity; miss; mnm; morbidity; mortality; national; non; number; obstetric; outcome; pandemic; pltc; pregnancy; prevalence; pulmonary; rate; ratio; respiratory; respiratory disease; review; risk; severe; severe maternal; severe respiratory; severity; smo; study; surveillance; tested; treatment; vaccination; virus; women
- versions: original; plain text
- cord-304718-w469n0o8
- author: Wang, Yan
- title: Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection
- date: 2009-05-01
- words: 2600
- flesch: 46
- summary: To examine the hypothesis that polymorphisms of the MASP2 gene in SARS patients are genetic factors that influence infection susceptibility, we studied MASP2 gene polymorphisms in DNA from two groups of Chinese SARS patients, and compared these with normal blood donors from the same region. Our data do not suggest a role for MASP2 polymorphisms in SARS susceptibility in northern and southern China.
- keywords: acute; alleles; analysis; association; beijing; binding; china; chinese; complement; controls; coronavirus; cov; deficiency; disease; dna; factors; frequencies; gene; genetic; genotype; guangzhou; hla; individuals; infection; lectin; mannan; masp2; mbl; patients; pcr; polymorphisms; protein; respiratory; rs12711521; rs2273346; sample; sars; serine; severe; significant; snps; study; susceptibility; syndrome; system
- versions: original; plain text
- cord-306175-p5rtp31m
- author: Weissbrich, Benedikt
- title: Frequent detection of bocavirus DNA in German children with respiratory tract infections
- date: 2006-07-11
- words: 3232
- flesch: 52
- summary: Respiratory tract infections are a major cause of human morbidity and are caused by a broad spectrum of microbial agents. Viruses account for the largest number of respiratory tract infections.
- keywords: age; assay; association; bocavirus; children; clinical; data; detection; different; diseases; distribution; dna; frequency; germany; hbov; high; human; infants; infections; influenza; lower; median; npa; npas; number; patients; pcr; positive; possible; previous; products; respiratory; rsv; samples; screening; studies; study; tract; viruses; years
- versions: original; plain text
- cord-307307-b5yl88mh
- author: Lau, Joseph TF
- title: Avoidance behaviors and negative psychological responses in the general population in the initial stage of the H1N1 pandemic in Hong Kong
- date: 2010-05-28
- words: 4711
- flesch: 47
- summary: The cost of assurance by Hong Kong government is however, high -with early summer closure of all primary schools and kindergarten and a number of secondary schools, 10 billion Hong Kong dollars being spent (1.2 billion US$) to purchase H1N1 vaccines and reorganization of the health services to accommodate escalating infection figures are not insubstantial. Scholars estimated that a loss of HK$15 billion in spending on goods and services in Hong Kong domestic economy was attributable to the SARS epidemic [10] .
- keywords: avian; avoidance; avoidance behaviors; behaviors; beliefs; bodily; cases; community; control; countries; distress; early; emotional; epidemic; family; general; government; h1n1; health; high; hong; hong kong; influenza; june; kong; likely; members; modes; multivariate; negative; outbreak; pandemic; perceptions; phase; places; population; psychological; public; respondents; responses; sars; severe; studies; study; table; telephone; transmission; unconfirmed; variables
- versions: original; plain text
- cord-308655-zntwwqod
- author: Dabisch-Ruthe, Mareike
- title: Comparison of three multiplex PCR assays for the detection of respiratory viral infections: evaluation of xTAG respiratory virus panel fast assay, RespiFinder 19 assay and RespiFinder SMART 22 assay
- date: 2012-07-24
- words: 5803
- flesch: 45
- summary: Furthermore, this is the first screening study determining the incidence of infections with respiratory pathogens in a mechanically ventilated patient cohort developing an atypical pneumonia during post-operative monitoring using multiplex PCR assays. Analysis of clinical samples showed a high concordance of detected viruses by the RespiFinder-19 compared to monoplex tests.
- keywords: 229e; adenovirus; adv; amplification; analysis; analytical; assay; clinical; comparison; concentrations; control; copies; cov; detection; different; dna; elution; fast; germany; hmpv; infections; influenza; inoculated; manufacturer; material; methods; monoplex; multiplex; number; panel; parallel; pathogens; patients; pcr; positive; probe; quantified; reaction; real; respifinder-19; respiratory; results; rhinovirus; routine; rsv; rvp; samples; sensitivity; smart-22; step; study; table; time; viral; viruses; volume; xtag
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- cord-311382-ioemd0ij
- author: Tellier, Raymond
- title: Recognition of aerosol transmission of infectious agents: a commentary
- date: 2019-01-31
- words: 5341
- flesch: 32
- summary: An epidemiologic study of radiant disinfection of air in day schools Airborne spread of measles in a suburban elementary school Measles outbreak in a pediatric practice: airborne transmission in an office setting Airborne transmission of measles in a physician's office Aerial Dissemination of pulmonary tuberculosis a two year study of contagion in a tuberculosis ward Ultraviolet irradiation of infected air: comparative infectiousness of different patients The infectiousness of tuberculosis patients coinfected with HIV Spread of tuberculosis via recirculated air in a naval vessel: the Byrd study Nosocomial transmission of tuberculosis associated with a draining abscess Transmission of multidrug-resistant Mycobacterium tuberculosis during a long airplane flight Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission What was the primary mode of smallpox transmission? Implications for biodefense Front Cell Infect Microbiol An airborne outbreak of smallpox in a German hospital and its significance with respect to other recent outbreaks in Europe Cluster of SARS among medical students exposed to single patient Transmission of the severe acute respiratory syndrome on aircraft Evidence of airborne transmission of the severe acute respiratory syndrome virus Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Severe acute respiratory syndrome vs. the Middle East respiratory syndrome Coronaviruses: severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus in travelers Clinical features and viral diagnosis of two cases of infection with Middle East respiratory syndrome coronavirus: a report of nosocomial transmission First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study A family cluster of Middle East respiratory syndrome coronavirus infections related to a likely unrecognized asymptomatic or mild case Clinical progression and viral load in a community outbreak of coronavirusassociated SARS pneumonia: a prospective study Kinetics and pattern of viral excretion in biological specimens of two MERS-CoV cases Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndrome Differential expression of the MERS-coronavirus receptor in the upper respiratory tract of humans and dromedary camels Review of aerosol transmission of influenza a virus Aerosol transmission of influenza a virus: a review of new studies Airborne transmission of influenza: implications for control in healthcare and community settings Aerosol transmission is an important mode of influenza a virus spread Human influenza resulting from aerosol inhalation The effect of environmental parameters on the survival of airborne infectious agents Interim Guidance for the Use of Masks to Control Influenza Transmission Characterization of Aerosols Generated During Patient Care Activities Influenza virus in human exhaled breath: an observational study Exhalation of respiratory viruses by breathing, coughing, and talking Viable influenza a virus in airborne particles from human coughs Viable influenza a virus in airborne particles expelled during coughs vs. Exhalations Influenza Other Respir Viruses EMIT Consortium Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community Concentrations and size distributions of airborne influenza a viruses measured indoors at a health Centre, a day-care Centre and on aeroplanes Exposure to influenza virus aerosols during routine patient care Quantification of Influenza Virus RNA in Aerosols in Patient Rooms Absence of detectable influenza RNA transmitted via aerosol during various human respiratory activities--experiments from Singapore and Hong Kong Influenza virus aerosols in human exhaled breath: particle size, culturability, and effect of surgical masks Establishment and clinical applications of a portable system for capturing influenza viruses released through coughing Exhaled aerosol transmission of pandemic and seasonal H1N1 influenza viruses in the ferret Transmission of viral respiratory infections in the home Epidemiology and prevention of pediatric viral respiratory infections in health-care institutions Influenza in the acute hospital setting Transmission of influenza: implications for control in health care settings
- keywords: absence; acute; aerosol; agents; airborne; airborne transmission; airflows; authors; care; cases; chickenpox; clinical; control; coronavirus; cov; diameter; different; direct; disease; droplets; east; ebola; environmental; epidemiological; example; experimental; exposure; family; healthcare; high; human; illness; implications; infected; infection; influenza; large; likely; lrt; measles; mers; middle; mode; negative; outbreak; particles; pathogens; patients; possible; potential; ppe; range; recent; respiratory; review; rna; route; sars; severe; short; significant; single; size; small; smallpox; spread; studies; study; suspension; syndrome; tract; transmissible; transmission; tuberculosis; varicella; ventilation; viral; virus; viruses
- versions: original; plain text
- cord-312222-aw5849rc
- author: Österdahl, Marc F.
- title: Detecting SARS-CoV-2 at point of care: preliminary data comparing loop-mediated isothermal amplification (LAMP) to polymerase chain reaction (PCR)
- date: 2020-10-20
- words: 3959
- flesch: 48
- summary: However, as the pandemic has progressed, it has become apparent that there is no true gold standard for COVID-19 testing with highly-anticipated antibody testing not always proving helpful; even in mild disease, antibodies in PCR positive patients may not be detected [22] . Low temperatures (< 36°C were detected in a minority of COVID PCR positive patients ( Table 3 ).
- keywords: accuracy; amplification; assay; care; cases; clinical; coronavirus; cov-2; covid-19; day; days; detection; diagnostic; disease; early; gold; high; home; isothermal; laboratory; lamp; loop; low; method; microsensdx; need; negative; novel; outbreak; patients; pcr; poc; positive; rapid; residents; respiratory; results; reverse; samples; sars; sensitivity; single; specificity; spread; standard; studies; study; swabs; table; temperature; testing; tests; transcription; value
- versions: original; plain text
- cord-312522-mymgnf8z
- author: Nelson, Megan M.
- title: Rapid molecular detection of macrolide resistance
- date: 2019-02-12
- words: 5149
- flesch: 35
- summary: Because the microbiome is a dynamic entity in which antimicrobial resistance genes are shared among members [53] , it is clinically vital to monitor levels of antibiotic resistance genes in commensal bacteria of healthy individuals that may contribute to more severe disease. While initially identified in S. pyogenes and S. pneumoniae [33] it has since been identified in an extremely wide range of gram-positive and negative bacteria worldwide [37] consistent with horizontal transfer of antimicrobial resistance genes. Using purified DNA, a panel of bacteria cultures, and broth dilution antimicrobial resistance testing, we demonstrate extreme sensitivity and specificity of the RPA assay, and we confirm that positive results correctly predict antimicrobial resistance.
- keywords: accession; acid; agalactiae; amplification; antibiotic; antimicrobial; antimicrobial resistance; assay; bacterial; clinical; commensal; copies; culture; detection; diagnostic; dilution; disease; dna; efflux; erythromycin; fig; genome; genomic; group; healthy; human; infection; isothermal; levels; lysates; macrolide; mef(a; methods; mgas10394; microbiome; min; molecular; negative; new; non; nucleic; pathogens; patient; pcr; pneumoniae; polymerase; positive; presence; primers; probe; pyogenes; rapid; raw; reaction; real; recombinase; resistance; results; rpa; salivarius; samples; sensitive; sensitivity; signal; single; specific; specificity; strains; streptococcus; study; target; testing; thermofisher; time; total; virus; work
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- cord-312544-vip4jtlv
- author: Ng, Lisa FP
- title: Specific detection of H5N1 avian influenza A virus in field specimens by a one-step RT-PCR assay
- date: 2006-03-02
- words: 2145
- flesch: 52
- summary: A total of 145 field samples comprising of known and suspect cases from chickens, ducks and muscovies isolated from Vietnam and Malaysia during the 2004 to 2005 outbreak were tested for H5N1 RNA (Table Detection of H5N1 avian influenza key: cord-312544-vip4jtlv authors: Ng, Lisa FP; Barr, Ian; Nguyen, Tung; Noor, Suriani Mohd; Tan, Rosemary Sok-Pin; Agathe, Lora V; Gupta, Sanjay; Khalil, Hassuzana; To, Thanh Long; Hassan, Sharifah Syed; Ren, Ee-Chee title: Specific detection of H5N1 avian influenza A virus in field specimens by a one-step RT-PCR assay date: 2006-03-02 journal: BMC Infect Dis DOI: 10.1186/1471-2334-6-40 sha: doc_id: 312544 cord_uid: vip4jtlv BACKGROUND: Continuous outbreaks of the highly pathogenic H5N1 avian influenza A in Asia has resulted in an urgent effort to improve current diagnostics to aid containment of the virus and lower the threat of a influenza pandemic.
- keywords: assay; avian; avian influenza; detection; disease; field; fig; h5n1; human; influenza; methods; min; pathogenic; pcr; positive; primers; proteins; results; reverse; rna; samples; sensitive; sensitivity; set; specific; specificity; step; strains; study; subtypes; table; transcription; vietnam; viral; virus; viruses
- versions: original; plain text
- cord-313054-w90eitw9
- author: Mobaraki, Kazhal
- title: Current epidemiological status of Middle East respiratory syndrome coronavirus in the world from 1.1.2017 to 17.1.2018: a cross-sectional study
- date: 2019-04-27
- words: 2190
- flesch: 51
- summary: The pattern of Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive epidemiological analysis of data from the Saudi Ministry of Health Comparative epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia and South Korea The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea Middle East respiratory syndrome coronavirus Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China Middle East respiratory syndrome coronavirus: review of the current situation in the world Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels Isolation of MERS coronavirus from a dromedary camel Dromedary camels and the transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) Zoonotic origin and transmission of Middle East respiratory syndrome coronavirus in the UAE World Organization Health Middle East respiratory syndrome Estimating the severity and subclinical burden of Middle East respiratory syndrome coronavirus infection in the Kingdom of Saudi Arabia Hadj ritual and risk of a pandemic Transmission scenarios for Middle East respiratory syndrome coronavirus (MERS-CoV) and how to tell them apart Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia Middle East respiratory syndrome novel corona (MERS-CoV) infection. The authors take this opportunity to thank all the WHO personnel as well as reporting countries with confirmed MERS cases for data collection and sending the data to WHO.
- keywords: 17.1.2018; age; arabia; camels; cases; coronavirus; countries; cov; current; data; disease; east; epidemiological; exposure; global; health; infection; laboratory; mers; middle; mortality; outbreak; respiratory; results; risk; saudi; studies; study; syndrome; transmission; world
- versions: original; plain text
- cord-313529-xm76ae08
- author: Liu, Wen-Kuan
- title: Detection of human bocavirus from children and adults with acute respiratory tract illness in Guangzhou, southern China
- date: 2011-12-14
- words: 2970
- flesch: 53
- summary: HBoV infection has recently attracted increasing attention all over the world. [13] [14] , and only a few papers have described the characteristics of HBoV infection in adult patients [16, 25, 26] .
- keywords: acute; adults; analysis; arti; bocavirus; characteristics; children; china; clinical; complete; coronavirus; detection; disease; dna; gastroenteritis; genome; guangzhou; hbov; hku1; human; illness; infection; influenza; novel; old; pathogens; patients; pcr; phylogenetic; pneumonia; positive; potential; ratio; real; respiratory; samples; single; southern; studies; study; symptoms; table; time; tract; years
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- cord-314826-usfvulc2
- author: Sharifipour, Ehsan
- title: Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU
- date: 2020-09-01
- words: 4346
- flesch: 38
- summary: key: cord-314826-usfvulc2 authors: Sharifipour, Ehsan; Shams, Saeed; Esmkhani, Mohammad; Khodadadi, Javad; Fotouhi-Ardakani, Reza; Koohpaei, Alireza; Doosti, Zahra; EJ Golzari, Samad title: Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU date: 2020-09-01 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05374-z sha: doc_id: 314826 cord_uid: usfvulc2 BACKGROUND: COVID-19 is known as a new viral infection. To date, few studies have investigated bacterial superinfections in COVID-19 patients.
- keywords: acinetobacter; admission; antibiotics; associated; aureus; bacterial; baumannii; care; cases; clinical; coronavirus; covid-19; days; discharged; diseases; expired; high; hospital; icu; icus; infections; influenza; intensive; iran; isolated; klebsiella; length; medical; methicillin; mortality; mrsa; nosocomial; pandemic; patients; pneumonia; positive; rate; resistant; respiratory; risk; secondary; severe; spp; staphylococcus; stay; strains; studies; study; tract; underlying; units; university; ventilator; viral; virus; years
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- cord-315866-6vcts4w3
- author: Chan, KC Allen
- title: Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study
- date: 2005-04-09
- words: 2555
- flesch: 43
- summary: Here, we showed that both susceptibility and disease outcome of SARS infection were not associated with ACE I/D polymorphism among Chinese patients in contrast to the recent report studying Vietnamese patients [10] . A recent study has suggested that the deletion allele (D allele) of the angiotensin converting enzyme (ACE) gene is associated with hypoxemia in SARS patients.
- keywords: ace; acute; age; allele; analysis; angiotensin; ards; association; care; chinese; control; coronavirus; difference; disease; distributions; enzyme; frequencies; genetic; genotype; genotypic; infection; intensive; outcome; patients; polymorphism; progression; requirement; respiratory; sars; sars patients; severe; significant; study; subjects; susceptibility; syndrome
- versions: original; plain text
- cord-316245-n6tmn4ph
- author: Cui, Binglin
- title: Viral aetiology of acute respiratory infections among children and associated meteorological factors in southern China
- date: 2015-03-13
- words: 4999
- flesch: 39
- summary: Characteristics and the prevalence of respiratory viruses and the correlation with climatic factors of hospitalized children in Suzhou children's hospital Seasonal influenza activity in Hong Kong and its association with meteorological variations Comparison of the incidence of influenza in relation to climate factors during 2000-2007 in five countries Epidemiology and seasonality of respiratory viral infections in hospitalized children in Kuala Lumpur, Malaysia: a retrospective study of 27 years Seasonal patterns of viral and bacterial infections among children hospitalized with community-acquired pneumonia in a tropical region A seasonal model to simulate influenza oscillation in Tokyo Association of meteorological factors with childhood viral acute respiratory infections in subtropical China: an analysis over 11 years Seasonal trends of viral respiratory tract infections in the tropics Epidemiology of respiratory syncytial virus infection among paediatric patients in Hong Kong: seasonality and disease impact Climatic, temporal, and geographic characteristics of respiratory syncytial virus disease in a tropical island population Effects of air temperature and relative humidity on coronavirus survival on surfaces Incidence of common respiratory viral infections related to climate factors in hospitalized children in Hong Kong Distribution and risk factors of 2009 pandemic influenza A (H1N1) in mainland China Comparison of the NucliSens Basic kit (Nucleic Acid Sequence-Based Amplification) and the Argene Biosoft Enterovirus Consensus Reverse Transcription-PCR assays for rapid detection of enterovirus RNA in clinical specimens Continued seasonal circulation of enterovirus D68 in the Netherlands Rhinovirus C and respiratory exacerbations in children with cystic fibrosis Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • The role of infections and coinfections with newly identified and emerging respiratory viruses in children High rate of viral identification and coinfections in infants with acute bronchiolitis Viruses in community-acquired pneumonia in children aged less than 3 years old: High rate of viral coinfection Impact of viral infections in children with community-acquired pneumonia: results of a study of 17 respiratory viruses Multipathogen infections in hospitalized children with acute respiratory infections Polymicrobial Acute Respiratory Infections in a Hospital-Based Pediatric Population Development and evaluation of a four-tube real time multiplex PCR assay covering fourteen respiratory viruses, and comparison to its corresponding single target counterparts Real-time reverse transcription-PCR assay for comprehensive detection of human rhinoviruses Clusters of acute respiratory illness associated with human enterovirus 68-Asia, Europe, and United States multi-centre study in the Netherlands examining laboratory ability to detect enterovirus 68, an emerging respiratory pathogen Surveillance of 16 respiratory viruses in patients with influenza-like illness in Nanjing Etiology and seasonality of viral respiratory infections in rural honduran children Acute viral respiratory infection in children under 5 years: Epidemiological study in two centers in Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from RNA viruses in community-acquired childhood pneumonia in semi-urban Nepal; a cross-sectional study Broad respiratory virus detection in infants hospitalized for bronchiolitis by use of a multiplex RT-PCR DNA microarray system Co-infections with influenza and other respiratory viruses The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010 Mixed respiratory virus infections Viral etiology of common cold in children Associations between Pathogens in the Upper Respiratory Tract of Young Children: Interplay between Viruses and Bacteria Frequent detection of respiratory viruses without symptoms: toward defining clinically relevant cutoff values Detection and typing by molecular techniques of respiratory viruses in children hospitalized for acute respiratory infection in Rome, Italy Multiple simultaneous viral infections in infants with acute respiratory tract infections in Spain Viral etiology of influenza-like illnesses in cameroon Viral etiology of acute respiratory tract infections in children presenting to hospital: role of polymerase chain reaction and demonstration of multiple infections Comparison of nasopharyngeal flocked swabs and nasopharyngeal wash collection methods for respiratory virus detection in hospitalized children using real-time polymerase chain reaction Evidence from multiplex molecular assays for complex multipathogen interactions in acute respiratory infections Are meteorological parameters associated with acute respiratory tract infections?
- keywords: acute; adv; analysis; aris; associations; average; cases; children; china; clinical; common; control; data; detection; enteroviruses; etiology; factors; flua; germany; hbov; hcov; high; hospitalized; hrv; human; humidity; infections; influenza; likely; meteorological; multiple; negative; pathogens; patients; pcr; pediatric; piv3; piv4; positive; presence; prevalence; rates; real; respiratory; respiratory infections; respiratory viruses; rsv; seasonal; shantou; single; studies; study; table; temperature; time; tract; university; velocity; viral; viruses; wind; year
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- cord-316493-wszoi6p2
- author: Zhou, Weimin
- title: First infection by all four non-severe acute respiratory syndrome human coronaviruses takes place during childhood
- date: 2013-09-16
- words: 4341
- flesch: 53
- summary: High proportions of children and adults in Beijing show anti-S IgG seropositivity against the four HCoVs, and anti-S IgM antibodies were detected in the sera of asymptomatic children. We propose that an IFA for the detection of IgG against structural (N and S) proteins of non-SARS HCoV may be suitable for seroepidemiological studies.
- keywords: acute; adults; age; anti; antibodies; antibody; assay; beijing; cells; children; china; coronavirus; detection; elisa; expression; figure; general; group; hcov; hcov-229e; healthy; hku1; human; ifa; igg; igm; individual; infection; mouse; nl63; non; novel; nucleocapsid; oc43; population; positive; prevalence; protein; rate; recombinant; respiratory; results; s igg; samples; sars; seropositivity; seroprevalence; serum; severe; significant; specific; spike; study; syndrome; years
- versions: original; plain text
- cord-318057-xagh68jc
- author: Gunson, Rory N
- title: During the summer 2009 outbreak of "swine flu" in Scotland what respiratory pathogens were diagnosed as H1N1/2009?
- date: 2011-07-13
- words: 2743
- flesch: 51
- summary: These assays have been developed by the WOSSVC and used as the frontline test for respiratory samples since 2005. As a result, PCR methods may be required to investigate influenza negative samples and in low prevalence periods, such as the time period examined in this study, PCR may also be required to confirm positive results.
- keywords: april; assay; authors; cases; clinical; confidence; criteria; data; detection; h1n1/2009; health; infection; influenza; interval; july; negative; number; outbreak; parainfluenza; pathogens; patients; pcr; period; real; respiratory; results; rtrt; samples; scotland; screen; specific; study; summer; swine; time; virus; viruses
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- cord-318340-hptjqmrl
- author: Xiang, Nijuan
- title: Lessons from an active surveillance pilot to assess the pneumonia of unknown etiology surveillance system in China, 2016: the need to increase clinician participation in the detection and reporting of emerging respiratory infectious diseases
- date: 2019-09-03
- words: 4330
- flesch: 33
- summary: We reviewed medical records for documented exposure history associated with respiratory infectious diseases, collected throat samples that were tested for seasonal and avian influenza, and interviewed clinicians regarding reasons for reporting or not reporting PUE cases. We described and analyzed the proportion of PUE cases reported and clinician awareness of and practices related to the PUE system.
- keywords: ari; avian; case; case definition; cdc; china; clinicians; control; data; definition; disease; documented; evaluation; exposures; fuyang; health; history; hospital; illnesses; infections; influenza; information; knowledge; laboratory; local; lu'an; medical; national; number; officers; patients; pneumonia; public; pue; pue case; pue system; records; relevant; reporting; respiratory; specimens; surveillance; system; testing; training; unknown; virus; years
- versions: original; plain text
- cord-318984-8m9ygzn5
- author: Chen, Yin-Yin
- title: Surveillance on secular trends of incidence and mortality for device–associated infection in the intensive care unit setting at a tertiary medical center in Taiwan, 2000–2008: A retrospective observational study
- date: 2012-09-10
- words: 4304
- flesch: 40
- summary: In the analysis of long-term changes in infection rates or mortality rates, we must consider whether changes in the population, advances in laboratory diagnostic techniques, changes in exposure to risk factors, microbial culture and other factors lead to increased or decreased rates. MRSA infection rates have been reduced by year from 2006.
- keywords: analysis; antibiotic; antimicrobial; aureus; baumannii; blood; bloodstream; care; catheter; cauti; cdc; central; clinical; common; cons; control; culture; dai; dais; data; days; device; disease; factors; healthcare; hospital; icu; incidence; infection; intensive; isolates; laboratory; manuscript; medical; microorganisms; mortality; mrsa; nhsn; nis; nosocomial; number; pathogens; patients; period; pneumonia; prognostic; program; prospective; rates; report; resistant; significant; spp; staphylococcus; study; surveillance; system; taiwan; teaching; vap; ventilator
- versions: original; plain text
- cord-319504-jb455t9p
- author: Suess, Thorsten
- title: The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011
- date: 2012-01-26
- words: 6955
- flesch: 46
- summary: However, one subgroup-analysis (restricting intervention households to those where intervention started within 36 h of symptom onset) The reason for the high SAR of 25% in MH households from the 2010/11 season (with 35% the SAR was even higher when only households with Influenza-B positive index patients were considered) remains unclear.
- keywords: 2010/11; adherence; adults; analysis; cases; children; cluster; contacts; control; daily; data; day; days; definition; effect; facemasks; germany; group; h1n1; hand; hand hygiene; higher; household; hygiene; ili; implementation; index; index patients; infection; influenza; intention; intervention; laboratory; manuscript; measures; members; mh group; npi; number; onset; pandemic; participants; patients; pdm09; period; possible; protective; protocol; respiratory; results; sar; season; secondary; significant; studies; study; symptom; table; times; transmission; trial; variables; virus; wearing; years
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- cord-320808-taj5swwc
- author: Lu, Guilan
- title: An outbreak of acute respiratory infection at a training base in Beijing, China due to human adenovirus type B55
- date: 2020-07-23
- words: 4935
- flesch: 49
- summary: Abbreviations PCR: Polymerase chain reaction; ARI: Acute respiratory infection; HAdV: Human adenovirus; ITR: Inverted terminal repeat; CDC: Center for disease prevention and control; CAP: Community-acquired pneumonia; UTR: Untranslated region Adenovirus: epidemiology, global spread of novel serotypes, and advances in treatment and prevention New adenovirus species found in a patient presenting with gastroenteritis An outbreak of epidemic keratoconjunctivitis caused by a new intermediate adenovirus 22/H8 identified by molecular typing Epidemiology of severe pediatric adenovirus lower respiratory tract infections in Manitoba, Canada Community-acquired pneumonia requiring hospitalization among U.S. adults Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture Human adenovirus: viral pathogen with increasing importance Emergence and re-emergence of respiratory adenoviruses in the United States Computational analysis identifies human adenovirus type 55 as a re-emergent acute respiratory disease pathogen Computational analysis of two species C human adenoviruses provides evidence of a novel virus Novel human adenovirus strain Genetic content and evolution of adenoviruses The adenovirus genome contributes to the structural stability of the virion Adenovirus: an overview for pediatric infectious diseases specialists Outbreak of human adenovirus type 3 infection in a pediatric long-term care facility--Illinois Detection of three human adenovirus species in adults with acute respiratory infection in China Retrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China Molecular identification of adenovirus causing respiratory tract infection in pediatric patients at the University of Malaya Medical Center Lower respiratory tract infections due to adenovirus in hospitalized Korean children: epidemiology, clinical features, and prognosis Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing Epidemical features of HAdV-3 and HAdV-7 in pediatric pneumonia in Chongqing Two adenovirus serotype 3 outbreaks associated with febrile respiratory disease and pharyngoconjunctival fever in children under 15 years of age in Hangzhou, China, during 2011 Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province Epidemiology and transmission characteristics of human adenovirus type 7 caused acute respiratory disease outbreak in military trainees in East China Outbreak of acute respiratory disease in China caused by B2 species of adenovirus type 11 Outbreak of adenovirus type 55 infection in Israel An outbreak of acute respiratory disease in China caused by human adenovirus type B55 in a physical training facility A cluster of adenovirus type B55 infection in a neurosurgical inpatient department of a general hospital in Guangdong, China. It is possible that HAdV outbreaks differ in their seasonality based on relative humidity and temperature.
- keywords: accession; acute; adenovirus; analysis; ari; august; b11; b14; b55; base; beijing; bj01/2011/55; bjdx-01; case; cdc; china; chn; clinical; different; disease; emergent; epidemiological; fiber; fig; genbank; genes; genome; hadv; hexon; human; identical; index; infection; influenza; isolate; laboratory; min; normal; nucleotide; number; outbreak; pathogen; patients; pcr; penton; pneumonia; poly; range; respiratory; samples; sequence; severe; species; specimens; strains; students; study; symptoms; temperature; total; tract; training; type; usa; viral; viruses
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- cord-320928-flsaa1wx
- author: Aldohyan, Meshal
- title: The perceived effectiveness of MERS-CoV educational programs and knowledge transfer among primary healthcare workers: a cross-sectional survey
- date: 2019-03-21
- words: 5010
- flesch: 44
- summary: Mayo Clinic Implementing knowledge management practices in hospital-in-the-home units The role of advanced practice nurses in knowledge brokering as a means of promoting evidence-based practice among clinical nurses Knowledge, attitude, and practice toward MERS-CoV among primary health-care workers in Makkah Al-Mukarramah: an intervention study Knowledge and perception of health practitioners towards MERS-CoV in hail region, Kingdom of Saudi Arabia Knowledge and attitude towards the Middle East respiratory syndrome coronavirus among healthcare personnel in the southern region of Saudi Arabia Knowledge, attitudes and Behaviours of healthcare Workers in the Kingdom of Saudi Arabia to MERS coronavirus and other emerging infectious diseases Sense making and knowledge transfer: capturing the knowledge and wisdom of nursing leaders Nurses' participation in personal knowledge transfer: the role of leader-member exchange (LMX) and structural empowerment Knowledge communication: a key to successful crisis management L'accréditation, source de connaissance et d'enrichissement Using interactive workshops to prompt knowledge exchange: a realist evaluation of a knowledge to action initiative Culture as an issue in knowledge sharing: a means of competitive advantage academic conferences limited Understanding change and change management processes: a case study An educational programme for nursing college staff and students during a MERS-coronavirus outbreak in Saudi Arabia Questionnaire-based analysis of infection prevention and control in healthcare facilities in Saudi Arabia in regards to Middle East respiratory syndrome Middle East respiratory syndrome-related knowledge, preventive behaviours and risk perception among nursing students during outbreak Intra-firm knowledge transfer-a qualitative case study of knowledge transfer and its implications in a soft service firm Knowledge management practices in healthcare settings: a systematic review The importance of knowledge transfer between specialist and generic services in improving health care: a cross-national study of dementia care in England and the Netherlands Diffusion of Innovations Impaired memory retrieval correlates with individual differences in cortisol response but not autonomic response Expatriate knowledge transfer, subsidiary absorptive capacity, and subsidiary performance key: cord-320928-flsaa1wx authors: Aldohyan, Meshal; Al-Rawashdeh, Nedal; Sakr, Farouk M.; Rahman, Saeed; Alfarhan, Ali I.; Salam, Mahmoud title: The perceived effectiveness of MERS-CoV educational programs and knowledge transfer among primary healthcare workers: a cross-sectional survey date: 2019-03-21 journal: BMC Infect Dis DOI: 10.1186/s12879-019-3898-2 sha: doc_id: 320928 cord_uid: flsaa1wx BACKGROUND: Knowledge transfer of Middle East respiratory syndrome coronavirus (MERS-CoV) involves the dissemination of created/acquired information on MERS-CoV in hospitals, making this information accessible to all healthcare workers (HCWs).
- keywords: 0.001; arabia; authors; cases; community; comparison; control; coronavirus; cov; cov educational; crisis; data; disease; dissemination; east; educational; effectiveness; experience; hcws; healthcare; high; hospital; infection; information; job; knowledge; knowledge transfer; male; management; medical; mers; middle; negative; nurses; outbreak; participants; patients; perception; personal; pharmacists; physicians; pms; practice; prevention; primary; programs; quality; reported; research; respiratory; response; review; saudi; scores; setting; staff; statements; study; survey; syndrome; transfer; updates; work; workers; years
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- cord-321235-h3w8827o
- author: Cabrera Alvargonzalez, Jorge Julio
- title: Pooling for SARS-CoV-2 control in care institutions
- date: 2020-10-12
- words: 2844
- flesch: 52
- summary: As previous studies [9, 10, 16] , our results using pools showed an increase of 3-5 cycles in the Cq value between pooled tests and individual positive samples. Positive samples detected during Care Homes screening with Cq value below the third quartile were selected.
- keywords: care; circulation; clusters; control; coronavirus; cov-2; covid-19; detection; distribution; galicia; gene; global; homes; individual; infection; institutions; low; number; p20; pcr; people; pooling; pools; positive; prevalence; residents; resources; samples; sars; screening; sensitivity; sp5; strategy; study; testing; tests; transmission; values; viral; workers
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- cord-321549-r7bmtloy
- author: Jendrny, Paula
- title: Scent dog identification of samples from COVID-19 patients – a pilot study
- date: 2020-07-23
- words: 3461
- flesch: 47
- summary: Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review Diagnostic accuracy of canine scent detection in early-and late-stage lung and breast cancers Trained dogs identify people with malaria parasites by their odour Using dog scent detection as a point-of-care tool to identify toxigenic clostridium difficile in stool Canine detection of the volatilome: a review of implications for pathogen and disease detection Realtime detection of a virus using detection dogs Biomedical scent detection dogs: would they pass as a health technology? Furthermore, detection dogs were provided both negative control samples with and without previous BPL treatment to exclude hydrolysed BPL as a potential distracting reagent.
- keywords: additional; average; blinded; bpl; control; coronavirus; correct; cov-2; covid-19; current; data; ddts; detection; device; diagnostic; different; disease; dogs; false; file; high; hole; human; identification; indications; individuals; infected; infection; medical; negative; new; non; pandemic; patients; pcr; people; positive; randomised; rate; respiratory; results; saliva; samples; sars; scent; screening; sensitivity; specificity; study; testing; time; training; video; virus; vocs
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- cord-321704-jozrgcq3
- author: Tan, Xin Quan
- title: Respiratory viral pathogens among Singapore military servicemen 2009 – 2012: epidemiology and clinical characteristics
- date: 2014-04-15
- words: 3863
- flesch: 44
- summary: respiratory viral panels for the diagnosis of respiratory viral infections in adults R: A language and environment for statistical computing Prevalence and seasonality of influenza-like illness in children Outbreak of pandemic influenza A (H1N1-2009) in Singapore Effectiveness of pandemic H1N1-2009 vaccination in reducing laboratory confirmed influenza infections among military recruits in tropical Singapore Broad spectrum respiratory pathogen analysis of throat swabs from military recruits reveals interference between rhinoviruses and adenoviruses Viral etiology of influenza-like illnesses in Evaluation of an influenza-like illness case definition in the diagnosis of influenza among patients with acute febrile illness in Cambodia Seasonal variations of 15 respiratory agents illustrated by the application of a multiplex polymerase chain reaction assay Rapid multiplex nested PCR for detection of respiratory viruses Influenza-like illness sentinel surveillance in Peru Nationwide surveillance of 18 respiratory viruses in patients with influenza-like illnesses: a pilot feasibility study in the French Sentinel Network Aetiology of influenza-like illness in adults includes parainfluenzavirus type 4 Respiratory viruses and influenza-like illness: a survey in the area of Rome Dual respiratory virus infections Respiratory viral infections during the 2009-2010 winter season in Central England, UK: incidence and patterns of multiple virus co-infections Relationship between humidity and influenza A viability in droplets and implications for influenza's seasonality Fever in respiratory virus infections Clinical signs and symptoms predicting influenza infection Differing symptom patterns in early pandemic vs seasonal influenza infections Predicting influenza infections during epidemics with use of a clinical case definition Understanding the symptoms of the common cold and influenza Influenza-like illness criteria were poorly related to laboratory-confirmed influenza in a sentinel surveillance study Clinical and financial benefits of rapid detection of respiratory viruses: an outcomes study Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • As influenza viruses have accounted for only between 10.1% to 53.0% of all ILI cases [15] [16] [17] , it is important to understand the contribution of other respiratory pathogens to overall morbidity and to determine their epidemiological distribution and clinical presentation.
- keywords: a(h1n1)pdm09; adults; adv; agents; analysis; cases; characteristics; clinical; cough; cov; definition; differences; different; disease; etiologies; febrile; fever; fri; high; ili; illness; infections; influenza; laboratory; like; likely; military; mono; multiple; non; overall; pandemic; pathogens; patients; pcr; positive; possible; present; proportion; recruits; respiratory; seasonal; signs; similar; singapore; studies; study; surveillance; symptoms; tropical; vaccination; value; viral; viruses
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- cord-321848-qys8r6jo
- author: Liu, Nan
- title: An atypical winter outbreak of hand, foot, and mouth disease associated with human enterovirus 71, 2010
- date: 2014-03-04
- words: 3531
- flesch: 46
- summary: EV71 was first isolated in the United States (California) in 1969 and by the mid-1970s, EV71 outbreaks, characterized by central nervous system complications occurred in succession in Bulgaria and Hungary Full-length VP1 sequences from EV71 isolates were amplified with the primers EV71-VP1-F, GGKGCRCC CAAYACWGCYT and EV71-VP1-R, CCVCCRCAAT CHCCWGGYT, resulting in a 981-bp amplicon.
- keywords: 107; acid; amino; analysis; atypical; c4a; cases; characteristics; china; city; disease; enterovirus; epidemiological; epidemiology; ev71; figure; foot; hand; hfmd; human; isolates; lineage; linyi; mild; molecular; mouth; mouth disease; nervous; outbreak; patients; pcr; phylogenetic; position; positive; primers; province; region; respiratory; rna; samples; sequences; severe; shandong; specimens; strains; study; subgenotype; substitution; symptoms; system; throat; viral; viruses; vp1; winter
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- cord-322202-n6qe38bh
- author: Saiki-Macedo, Stephanie
- title: Identfication of viral and bacterial etiologic agents of the pertussis-like syndrome in children under 5 years old hospitalized
- date: 2019-01-21
- words: 3885
- flesch: 37
- summary: Estimates of world-wide distribution of child deaths from acute respiratory infections Viral and Bacterial Etiologies of Acute Respiratory Infections Among Children Under 5 Years in Senegal Acute respiratory infections among under-5 children in India: a situational analysis Global burden of acute respiratory infections in children: implications for interventions Clinical utility of PCR for common viruses in acute respiratory illness Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang Virological diagnosis in communityacquired pneumonia in immunocompromised patients Prevalence of non-influenza respiratory viruses in acute respiratory infection cases in Mexico Epidemiology of acute respiratory infections in children of developing countries Prevalence of bacterial pathogens in children with acute respiratory infection in Addis Ababa High prevalence of mycoplasma pneumoniae and chlamydia pneumoniae in children with acute respiratory infections from Lima Molecular etiological profile of atypical bacterial pathogens, viruses and coinfections among infants and children with community-acquired pneumonia admitted to a national hospital in Lima Use of multiplex PCR for diagnosis of bacterial infection respiratory mixed Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals Bacterial and viral pathogen spectra of acute respiratory infections in under-5 children in hospital settings in Dhaka city Pertussis: a reemerging and an underreported infectious disease Estimating the prevalence of coinfection with influenza virus and the atypical bacteria Bordetella pertussis, Chlamydophila pneumoniae, and mycoplasma pneumoniae Incidence and severity of pertussis in infants with a respiratory syncytial virus infection Does virus-bacteria coinfection increase the clinical severity of acute respiratory infection Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections Pertussis: a persistent cause of morbidity and mortality in young infants Evaluation of three influenza a and B real-time reverse transcription-PCR assays and a new 2009 H1N1 assay for detection of influenza viruses Epidemiology and clinical presentations of respiratory syncytial virus subgroups a and B detected with multiplex real-time PCR Pring-Akerblom P. Rapid and quantitative detection of human adenovirus DNA by real-time PCR Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays Alerta Epidemiológica: Tos Ferina (Coqueluche) Bordetella pertussis: an underreported pathogen in pediatric respiratory infections, a prospective cohort study Childhood Whooping Cough Vaccine Protects Most Children For At Least 5 years Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies Detection of Bordetella pertussis in infants suspected to have whooping cough Incidence of respiratory viruses in Peruvian children with acute respiratory infections Epidemiology and seasonality of acute respiratory infections in hospitalized children over four consecutive years Adenovirus respiratory tract infections in infants: a retrospective chart-review study Pertussis-like syndrome associated with adenovirus presenting with hyperleukocytosis: case report Whooping-cough due to adenovirus The role of adenoviruses in the pertussis syndrome Etiologic spectrum and occurrence of coinfections in children hospitalized with communityacquired pneumonia Pertussis accompanying recent mycoplasma infection in a 10-year-old girl PCR versus serology for diagnosing mycoplasma pneumoniae infection: a systematic review & meta-analysis Laboratory diagnosis of mycoplasma pneumoniae infection Incidence and burden of pertussis among infants less than 1 year of age Carriage of mycoplasma pneumoniae in the upper respiratory tract of symptomatic and asymptomatic children: an observational study Respiratory viral infections in infants with clinically suspected pertussis Respiratory viruses and B pertussis co-infections: A frequent occurrence in children hospitalized with B pertussis key: cord-322202-n6qe38bh authors: Saiki-Macedo, Stephanie; Valverde-Ezeta, Jorge; Cornejo-Tapia, Angela; Castillo, Maria Esther; Petrozzi-Helasvuo, Verónica; Aguilar-Luis, Miguel Angel; del Valle, Luis J.; Cieza-Mora, Erico; Bada, Carlos; del Aguila, Olguita; Silva-Caso, Wilmer; Martins-Luna, Johanna; Vasquez-Achaya, Fernando; del Valle-Mendoza, Juana title: Identfication of viral and bacterial etiologic agents of the pertussis-like syndrome in children under 5 years old hospitalized date: 2019-01-21 journal: BMC Infect Dis DOI: 10.1186/s12879-019-3671-6 sha: doc_id: 322202 cord_uid: n6qe38bh BACKGROUND: Acute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries.
- keywords: acute; additional; adenovirus; adv; agent; analysis; aris; association; atypical; bacterial; bordetella; cases; children; chlamydia; clinical; coinfection; common; cough; diagnosis; etiological; etiologies; file; high; infants; infections; influenza; months; mycoplasma; old; parainfluenza; pathogens; patients; pcr; pertussis; peruvian; pneumoniae; prevalence; previous; probable; respiratory; rsv; samples; study; symptoms; table; viral; virus; viruses; whooping; years
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- cord-324638-gwd8qin6
- author: Chiu, Rossa WK
- title: Automated extraction protocol for quantification of SARS-Coronavirus RNA in serum: an evaluation study
- date: 2006-02-09
- words: 3361
- flesch: 43
- summary: WHO: Summary of probable SARS cases with onset of illness from 1 A major outbreak of severe acute respiratory syndrome in Hong Kong Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome Serial analysis of the plasma concentration of SARS coronavirus RNA in pediatric patients with severe acute respiratory syndrome Effects of early corticosteroid treatment on plasma SARSassociated Coronavirus RNA concentrations in adult patients Fully automated nucleic acid extraction: MagNA Pure LC SARS molecular detection external quality assurance A new biometrical procedure for testing the equality of measurements from two different analytical methods. For serum SARS-CoV concentration at 10 5 copies/mL, the assay coefficient of variation was 47.4% for the manual RNA extraction and 51.0% when automated RNA extraction was used.
- keywords: acid; automated; compared; copies; cov; cov rna; external; extraction; instrument; kit; large; lysis; magna; manual; method; modified; nucleic; pcr; protocol; pure; quantitative; rna; rna extraction; sars; serum; serum sars; total; use; viral; volume
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- cord-324880-s1oqkqef
- author: Xu, Lili
- title: A fatal case associated with respiratory syncytial virus infection in a young child
- date: 2018-05-11
- words: 3289
- flesch: 41
- summary: RSV infections: state of the art The burden of respiratory syncytial virus infection in young children Updated guidance for Palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection Predicting deterioration in previously healthy infants hospitalized with respiratory syncytial virus infection Examination of neurological prognostic markers in patients with respiratory syncytial virus-associated encephalopathy Metagenomic analysis of viral genetic diversity in respiratory samples from children with severe acute respiratory infection in China Deciphering the bat virome catalog to better understand the ecological diversity of bat viruses and the bat origin of emerging infectious diseases Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody Neutralizing epitopes on the respiratory syncytial virus fusion glycoprotein Extrapulmonary manifestations of severe respiratory syncytial virus infection-a systematic review Risk factors for respiratory syncytial virus associated apnoea Neurological complications of respiratory syncytial virus infection: case series and review of literature Reflex apnoea response and inflammatory mediators in infants with respiratory tract infection Detection of subgroup B respiratory syncytial virus in the cerebrospinal fluid of a patient with respiratory syncytial virus pneumonia Respiratory syncytial virus-related encephalitis: magnetic resonance imaging findings with diffusion-weighted study The Spectrum and burden of influenza-associated neurological disease in children: combined encephalitis and influenza sentinel site surveillance from Australia PCR on cerebrospinal fluid to show influenzaassociated acute encephalopathy or encephalitis Influenza-associated acute encephalopathy in Japanese children in 1994-2002 Neurologic complications associated with novel influenza a (H1N1) virus infection in children Encephalitis and encephalopathy associated with an influenza epidemic in Japan Detection of influenza virus RNA by reverse transcription-PCR and proinflammatory cytokines in influenza-virus-associated encephalopathy This study was approved by the Ethical Review Committee of Beijing Children's Hospital. key: cord-324880-s1oqkqef authors: Xu, Lili; Gao, Hengmiao; Zeng, Jiansheng; Liu, Jun; Lu, Cong; Guan, Xiaolei; Qian, Suyun; Xie, Zhengde title: A fatal case associated with respiratory syncytial virus infection in a young child date: 2018-05-11 journal: BMC Infect Dis DOI: 10.1186/s12879-018-3123-8 sha: doc_id: 324880 cord_uid: s1oqkqef BACKGROUND: Respiratory syncytial virus (RSV) is the most common viral cause of pediatric bronchiolitis and pneumonia worldwide.
- keywords: acute; admission; analysis; aspirate; blood; body; brain; case; children; clinical; cns; complications; consent; cough; csf; days; death; detection; disease; edema; encephalitis; encephalopathy; fever; findings; heart; high; infants; infection; influenza; metagenomic; nasopharyngeal; negative; neurological; november; old; onset; oral; pathogen; patient; reads; related; respiratory; results; risk; rna; rsv; rsvb; sequence; severe; specimens; streptococcus; swab; symptoms; syncytial; temperature; viral; virus
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- cord-324942-zfvzxlj7
- author: Yu, Jianxing
- title: Comparison of the prevalence of respiratory viruses in patients with acute respiratory infections at different hospital settings in North China, 2012–2015
- date: 2018-02-08
- words: 4317
- flesch: 40
- summary: Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the global burden of disease study Mortality and Causes of Death Collaborators: Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the global burden of disease study Aetiological role of common respiratory viruses in acute lower respiratory infections in children under five years: a systematic review and meta-analysis Viral etiology of acute respiratory infections in hospitalized and outpatient children in Evaluation of viral co-infections in hospitalized and non-hospitalized children with respiratory infections using microarrays Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis Community-acquired pneumonia requiring hospitalization among U.S. adults The severe acute respiratory syndrome Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing Viral etiologies of hospitalized acute lower respiratory infection patients in China Prevalence of human metapneumovirus in adults with acute respiratory tract infection in Beijing Prevalence of human coronaviruses in adults with acute respiratory tract infections in Beijing Human rhinoviruses in Chinese adults with acute respiratory tract infection Differential seroprevalence of human bocavirus species 1-4 in Beijing Prevalence and clinical characteristics of human respiratory syncytial virus in Chinese adults with acute respiratory tract infection To save children's lives, China should adopt an initiative to speed introduction of pneumonia vaccines Coxsackievirus A21, enterovirus 68, and acute respiratory tract infection Respiratory infection with enterovirus genotype C117, China and Mongolia Human enterovirus genotype C104 WU and KI polyomavirus present in the respiratory tract of children, but not in immunocompetent adults R: A language and environment for statistical computing The management of communityacquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America Comparison of multiplex PCR assays and conventional techniques for the diagnostic of respiratory virus infections in children admitted to hospital with an acute respiratory illness Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response Viral pneumonia The burden of respiratory syncytial virus infection in young children Viral etiology of severe pneumonia among Kenyan infants and children Community-acquired pneumonia requiring hospitalization among U.S. children Respiratory syncytial virus: coinfection and paediatric lower respiratory tract infections Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics Influenza-associated hospitalizations in the United States Beijing Network for Adult Community-Acquired P: Viral etiology of communityacquired pneumonia among adolescents and adults with mild or moderate severity and its relation to age and severity The role of influenza in the severity and transmission of respiratory bacterial disease Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and metaanalysis The underrecognized burden of influenza in young children Association of rhinovirus infection with increased disease severity in acute bronchiolitis The impact of dual viral infection in infants admitted to a pediatric intensive care unit associated with severe bronchiolitis Detection of three human adenovirus species in adults with acute respiratory infection in China Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study Molecular identification and epidemiological features of human adenoviruses associated with acute respiratory infections in hospitalized children in southern China British Thoracic Society of Standards of Care Committee.
- keywords: acute; adenoviruses; adults; age; agents; analysis; aris; burden; cases; children; china; clinical; clinicians; common; different; disease; ed patients; frequent; global; hadvs; hospitalization; hospitalized; hospitals; hrvs; human; ifvs; infection; influenza; inpatient; lower; north; outpatient; patients; pneumonia; prevalence; previous; respiratory; results; rsv; rvs; settings; severe; severity; significant; specific; studies; study; tract; viral; viruses; years; young; young children
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- cord-325635-don9qjpz
- author: Turner, Paul
- title: Respiratory virus surveillance in hospitalised pneumonia patients on the Thailand-Myanmar border
- date: 2013-09-16
- words: 4306
- flesch: 43
- summary: key: cord-325635-don9qjpz authors: Turner, Paul; Turner, Claudia; Watthanaworawit, Wanitda; Carrara, Verena; Cicelia, Naw; Deglise, Carole; Phares, Christina; Ortega, Luis; Nosten, Francois title: Respiratory virus surveillance in hospitalised pneumonia patients on the Thailand-Myanmar border date: 2013-09-16 journal: BMC Infect Dis DOI: 10.1186/1471-2334-13-434 sha: doc_id: 325635 cord_uid: don9qjpz BACKGROUND: Pneumonia is a significant cause of morbidity and mortality in the developing world. United Nations High Commissioner for Refugees A community-based study of acute respiratory tract infection in Thai children Influenza pandemic plans: what about displaced populations? Committee for Coordination of Services to Displaced Persons in Thailand (CCSDPT) Influenza in refugees on the Thailand-Myanmar border WHO: Integrated management of childhood illness handbook In Pocket book of hospital care for children: guidelines for the management of common illnesses with limited resources Anonymous: BTS Guidelines for the management of community acquired pneumonia in adults Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages Comparison of nasopharyngeal and oropharyngeal swabs for the diagnosis of eight respiratory viruses by real-time reverse transcription-PCR assays Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus UNHCR: Health information system Epidemiology of respiratory viral infections in two long-term refugee camps in Kenya RNA viruses in community-acquired childhood pneumonia in semi-urban Nepal; a cross-sectional study The etiology of pneumonia in malnourished and well-nourished Gambian children Respiratory syncytial virus infection in tropical and developing countries Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance Viral etiology of severe pneumonia among Kenyan infants and children Clinical presentation and severity of viral community-acquired pneumonia in young Nepalese children Respiratory syncytial virus infection and disease in infants and young children observed from birth in Kilifi district Respiratory syncytial virus epidemiology in a birth cohort from Kilifi district, Kenya: infection during the first year of life High rates of pneumonia in children under two years of age in a South East Asian refugee population A high burden of respiratory syncytial virus associated pneumonia in children less than two years of age in a South East Asian refugee population The burden of influenza in East and South-East Asia: a review of the English language literature.
- keywords: adenovirus; admission; age; aged; associated; border; burden; camp; case; children; clinical; control; data; deaths; detection; diagnosis; enhanced; episodes; health; hmpv; hospital; human; incidence; infections; influenza; ipd; laboratory; likely; lower; lrti; maela; myanmar; npa; older; patients; pcr; pneumonia; population; refugee; respiratory; results; review; rsv; severe; significant; specimens; surveillance; syncytial; thailand; tract; viral; virus; viruses; world; years; young
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- cord-326632-botshfa1
- author: Abolfotouh, Mostafa A.
- title: Perception and attitude of healthcare workers in Saudi Arabia with regard to Covid-19 pandemic and potential associated predictors
- date: 2020-09-29
- words: 4136
- flesch: 49
- summary: Multiple regression analysis was used to identify predictors of high concern scores. Predictors of high concern scores were; HCWs of Saudi nationality (p < 0.001), younger age (p = 0.003), undergraduate education (p = 0.044), living with others (p = 0.003) working in the western region (p = 0.003) and direct contact with patients (p = 0.018).
- keywords: age; arabia; attitude; concern; concern score; contact; control; covid-19; data; direct; disease; domains; education; epidemic; finding; government; hcws; healthcare; high; higher; infection; level; living; low; medical; mers; mng; outbreak; overall; pandemic; participants; patients; perception; potential; predictors; regard; region; responses; risk; safe; saudi; scale; score; social; status; study; survey; total; western; workers; world
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- cord-327961-ysatxwph
- author: Wang, Le
- title: Risk factors of 90-day rehospitalization following discharge of pediatric patients hospitalized with mycoplasma Pneumoniae pneumonia
- date: 2019-11-12
- words: 3227
- flesch: 37
- summary: Because pneumonia is a complex heterogenous disease that can be caused by a variety of pathogens, 1) studying pneumonia patients with the same infectious pathogen can reduce heterogeneity, 2) exclusion of patients with underlying diseases can improve the ability to detect readmission risk factors associated with the current acute infections. There are 155 cases of single pathogen coinfection, 30 cases of two pathogens, 4 cases of 3 pathogens discharge; 2) at the index hospital stay, readmission patients manifested different characteristics; 3) co-infection with influenza A increased the risk of 90-day readmission.
- keywords: acute; age; analysis; body; cases; children; chronic; clinical; coinfection; common; community; cough; data; day; days; diagnosis; different; discharge; factors; hebei; hospital; index; infections; influenza; initial; laboratory; lower; mpp; multiple; mycoplasma; pathogens; patients; pcr; pediatric; pneumonia; positive; previous; province; rate; readmission; rehospitalization; related; respiratory; risk; stay; study; table; temperature; test
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- cord-328040-5qd05e4r
- author: Zhao, Xin-Ying
- title: Clinical characteristics of patients with 2019 coronavirus disease in a non-Wuhan area of Hubei Province, China: a retrospective study
- date: 2020-04-29
- words: 3419
- flesch: 50
- summary: To date, the clinical characteristics of COVID-19 patients in the non-Wuhan areas of Hubei Province in China have not been described. A considerable proportion of COVID-19 patients develop severe pneumonia, pulmonary edema, acute respiratory distress syndrome, and even multiple organ failure within a short time.
- keywords: ace2; acute; analysis; antiviral; cases; characteristics; chest; china; clinical; coronavirus; cov-2; covid-19; damage; data; disease; fig; group; higher; hospital; hubei; infection; injury; jingzhou; levels; mild; mortality; multiple; n =; non; novel; organ; patients; pneumonia; positive; province; qpcr; rate; receptor; respiratory; sars; severe; study; symptoms; syndrome; table; therapy; tract; treatment; wuhan
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- cord-328501-mbwgi56x
- author: Pang, Junxiong
- title: Risk factors for febrile respiratory illness and mono-viral infections in a semi-closed military environment: a case-control study
- date: 2015-07-25
- words: 5769
- flesch: 42
- summary: All known human rhinoviruses have been reported to be present in military recruits during respiratory infection Incidence, etiology, and impact Recent trends of pneumonia morbidity in US Naval personnel Keep your hands clean Influenza C virus infection in military recruits-symptoms and clinical manifestation Respiratory infections in the military Symptomatic respiratory syncytial virus infection in previously healthy young adults living in a crowded military environment Respiratory syncytial virus: an important cause of acute respiratory illness among young adults undergoing military training Viruses associated with acute respiratory infections in Royal Air Force personnel Patterns of infections with adenovirus types 4, 7 and 21 in military recruits during a 9-year survey The French Military influenza surveillance system (MISS): overview of epidemiological and virological results during four influenza seasons Novel influenza A(H1N1) outbreak among French armed forces in 2009: results of Military Influenza Surveillance System Outbreak of febrile respiratory illness caused by adenovirus at a South Korean military training facility: clinical and radiological characteristics of adenovirus pneumonia High isolation rate of adenovirus serotype 7 from South Korean military recruits with mild acute respiratory disease Acute lower respiratory tract infections in soldiers Building military influenza surveillance capacity in West Africa Outbreak of influenza A and B among military recruits: evidence from viral culture and polymerase chain reaction Outbreak of acute respiratory disease caused by human adenovirus type 7 in a military training camp in Shaanxi Outbreak of febrile respiratory illness associated with adenovirus 11a infection in a Singapore military training cAMP Differing clinical characteristics between influenza strains among young healthy adults in the tropics Respiratory viral pathogens among Singapore military servicemen 2009-2012: epidemiology and clinical characteristics Viral agents responsible for febrile respiratory illnesses among military recruits training in tropical Singapore Effectiveness of pandemic H1N1-2009 vaccination in reducing laboratory confirmed influenza infections among military recruits in tropical Singapore Effectiveness of seasonal influenza vaccinations against laboratory-confirmed influenza-associated infections among Singapore military personnel in 2010-2013.
- keywords: a(h1n1)pdm09; acute; adenovirus; age; analysis; aor; bias; bunkmates; camp; cases; clinical; closed; common; contact; controls; coxsackie; data; days; disease; echovirus; effects; environment; factors; febrile; fig; fri; higher; household; human; ill; illness; infection; influenza; lower; members; military; mono; mvi; non; outbreak; pandemic; pathogens; period; personnel; population; potential; previous; program; proportion; protective; recruits; respiratory; results; rhinovirus; risk; risk factors; saf; semi; significant; similar; singapore; smoking; study; surveillance; symptoms; tiv; tract; training; transmission; vaccination; vaccine; variables; viral; viruses
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- cord-328620-d2jrn1ip
- author: van Gageldonk-Lafeber, Arianne B
- title: Risk factors for acute respiratory tract infections in general practitioner patients in The Netherlands: a case-control study
- date: 2007-04-27
- words: 4248
- flesch: 47
- summary: Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution, Climate and Pollen Environmental risk factors for respiratory infections Respiratory infections in schoolchildren: co-morbidity and risk factors Risk factors for respiratory tract infections in children aged 2-5 years Day care centers and respiratory health Increased risk of chronic obstructive pulmonary diseases in coke oven workers: interaction between occupational exposure and smoking Risk factors for pulmonary tuberculosis in Russia: case-control study Smoking and the incidence of asthma during adolescence: results of a large cohort study in Germany The socio-economic status is related to the incidence of asthma and respiratory symptoms in adults Occupation, smoking, and chronic obstructive respiratory disorders: a cross sectional study in an industrial area of Catalonia Long-term air pollution exposure and living close to busy roads are associated with COPD in women Detection of respiratory syncytial virus in acute bronchiolitis in infants Improved detection of rhinoviruses in clinical samples by using a newly developed nested reverse transcription-PCR assay Evaluation of nested polymerase chain methods for the detection of human coronaviruses 229E and OC43 Type-specific identification of influenza viruses A, B and C by the polymerase chain reaction Respiratory tract infections: another reason not to smoke Environmental tobacco smoke exposure: prevalence and mechanisms of causation of infections in children Parental smoking and respiratory tract infections in children Housing characteristics and children's respiratory health in the Russian Federation Fungal levels in the home and lower respiratory tract illnesses in the first year of life Dampness in buildings and health. key: cord-328620-d2jrn1ip authors: van Gageldonk-Lafeber, Arianne B; van der Sande, Marianne AB; Heijnen, Marie-Louise A; Peeters, Marcel F; Bartelds, Aad IM; Wilbrink, Berry title: Risk factors for acute respiratory tract infections in general practitioner patients in The Netherlands: a case-control study date: 2007-04-27 journal: BMC Infect Dis DOI: 10.1186/1471-2334-7-35 sha: doc_id: 328620 cord_uid: d2jrn1ip BACKGROUND: Acute respiratory tract infections (ARTI) are an important public health problem.
- keywords: acute; age; analyses; arti; care; case; children; complaints; control; dampness; day; environmental; exposure; factors; general; health; home; household; infections; items; laboratory; nose; number; participants; pathogens; patients; persons; population; potential; public; reported; respiratory; risk; risk factors; smoking; studies; study; subjects; swabs; throat; tract; transmission; viral; visit
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- cord-329256-7njgmdd1
- author: Leecaster, Molly
- title: Modeling the variations in pediatric respiratory syncytial virus seasonal epidemics
- date: 2011-04-21
- words: 4540
- flesch: 45
- summary: The conclusions were that exponential growth was somewhat empirically related to seasonal epidemic characteristics and that variation in epidemic start date as well as the transmission parameter over epidemic years could explain variation in seasonal epidemic size. Three parameters associated with variation across epidemic years were estimated: 1) the temporal offset of the epidemic cycle (α), 2) detection fraction (f), and 3) transmission parameter (β).
- keywords: age; care; cases; characteristics; children; cycle; data; days; detection; disease; early; epidemic; epidemic size; epidemic year; estimates; exponential; fit; fraction; growth; health; lake; length; methods; model; modeling; observed; offset; parameter; peak; percent; period; population; rate; regression; respiratory; results; rse; rsv; rsv epidemic; salt; seasonal; seasonal epidemic; seasons; seidr; size; start; study; syncytial; testing; time; total; transmission; utah; values; variation; virus; years
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- cord-330607-zn4urrxc
- author: Chi, Qiong
- title: Differential diagnosis for suspected cases of coronavirus disease 2019: a retrospective study
- date: 2020-09-18
- words: 3248
- flesch: 44
- summary: Multiplex PCR nucleic acid testing helped differential diagnosis for suspected COVID-19 cases. We retrospectively collected the clinical data, including demographics, clinical manifestations, laboratory and radiological findings and contact history of suspected COVID-19 cases in isolation ward (single rooms) of Wenzhou Central Hospital from January 19, 2020 to February 20, 2020.
- keywords: acid; cases; characteristics; chest; clinical; cluster; common; confirmed; consolidation; coronavirus; count; cov-2; covid-19; diagnosis; differential; disease; fever; fig; ggos; group; history; hrct; influenza; lung; multiple; mycoplasma; negative; novel; nucleic; patchy; patients; pcr; pneumonia; positive; reduced; respiratory; result; sars; shadows; study; symptoms; testing; wbc
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- cord-333745-nwnt2tde
- author: Wang, Yi
- title: Clinical characteristics and laboratory indicator analysis of 67 COVID-19 pneumonia patients in Suzhou, China
- date: 2020-10-12
- words: 4400
- flesch: 45
- summary: Laboratory data showed that the WBC, N%, and CRP in Group B COVID-19 pneumonia patients were significantly higher than those of Group A patients, and the differences were statistically significant (P < 0.05). Therefore, the findings of statistical tests and p values should be interpreted with caution, and it is important to note that nonsignificant p values do not necessarily rule out the difference between Group A and Group B patients.
- keywords: addition; analysis; blood; cases; china; clinical; common; coronavirus; cov-2; covid-19; covid-19 pneumonia; data; days; difference; disease; fever; fib; function; general; group; group b; higher; hormone; hospital; imaging; indicators; laboratory; lesions; liver; lung; median; myoglobin; novel; number; oxygen; patients; pneumonia; pneumonia patients; respiratory; sars; severe; significant; study; suzhou; table; therapy; treatment; tuberculosis; value
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- cord-334424-z7ygy25e
- author: McCaw, James M
- title: Household transmission of respiratory viruses – assessment of viral, individual and household characteristics in a population study of healthy Australian adults
- date: 2012-12-11
- words: 4794
- flesch: 37
- summary: The lack of virological assessment of household secondary cases and the broad nature of the question used to establish the secondary case count in each house also contributes to uncertainty with regards to our assignment of temporally associated ILI to within-household transmission. key: cord-334424-z7ygy25e authors: McCaw, James M; Howard, Peter F; Richmond, Peter C; Nissen, Michael; Sloots, Theo; Lambert, Stephen B; Lai, Michael; Greenberg, Michael; Nolan, Terry; McVernon, Jodie title: Household transmission of respiratory viruses – assessment of viral, individual and household characteristics in a population study of healthy Australian adults date: 2012-12-11 journal: BMC Infect Dis DOI: 10.1186/1471-2334-12-345 sha: doc_id: 334424 cord_uid: z7ygy25e BACKGROUND:
- keywords: acute; adults; analysis; case; characteristics; children; cohort; community; coronavirus; data; days; demographic; episodes; events; factors; h1n1; healthy; household; household transmission; human; identification; ili; illness; infection; influence; influenza; interval; logistic; members; model; novel; number; onset; pandemic; participant; poisson; presence; primary; questionnaire; regression; respiratory; risk; sample; secondary; serial; shap; size; statistical; status; study; sub; symptoms; transmission; trial; vaccination; vaccine; virus; viruses; years
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- cord-334746-anqvdi2k
- author: Fischer, Doris
- title: Overcrowding in a neonatal intermediate care unit: impact on the incidence of multidrug-resistant gram-negative organisms
- date: 2019-04-29
- words: 4539
- flesch: 42
- summary: In this study, we implemented the available recommendations concerning neonatal MDRGN transmission into the daily life settings on NIMCU in the scenario of a short-term and high risk overcrowding period. Average incidence of nosocomial MDRGN transmissions in the NIMCU was calculated based on the monthly nosocomial MDRGN incidence of the last 12 months of ward-regular bed occupancy (PRAE-OV).
- keywords: baby; bed; beds; beta; breast; care; case; ceph; cloacae; colonization; contact; control; cumulative; data; day; detection; distance; enterobacteriaceae; extended; germany; healthcare; high; hospital; hygiene; impact; incidence; infection; intermediate; management; mdrgn; medical; microbiological; milk; mother; multidrug; negative; neonatal; neonates; nimcu; nosocomial; number; nurse; occupancy; organisms; overcrowding; parents; patients; period; positive; post; prae; ratio; regular; resistant; respiratory; risk; setting; skin; special; spread; staff; study; surveillance; total; training; transmission; uhf; unit; ward
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- cord-336663-fawcn6em
- author: Liu, Chunyan
- title: Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012
- date: 2015-10-01
- words: 4291
- flesch: 45
- summary: Among 3356 patients with ALRTIs, 194 (5.8 %) were found to have HAdV infection. HAdV infection was primarily confined to children (88.35 %) less than 5 years of age.
- keywords: acute; adenovirus; age; alrtis; analysis; beijing; c57; cases; children; china; clinical; data; department; detection; different; disease; fatal; fever; findings; gene; hadv; hadv infection; hexon; hospital; human; infected; infection; lower; molecular; multiple; participants; patients; pcr; pediatric; period; pneumonia; positive; respiratory; results; rsv; samples; severe; significant; single; species; specimens; study; test; tract; types; viral; viruses; years
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- cord-336975-28mtmw2z
- author: Sadeghi, Christine D
- title: Twelve years' detection of respiratory viruses by immunofluorescence in hospitalised children: impact of the introduction of a new respiratory picornavirus assay
- date: 2011-02-07
- words: 3033
- flesch: 35
- summary: multiplex PCR for the detection of respiratory picornavirus infections in children Epidemiological and clinical study of viral respiratory tract infections in children from Italy Comparison of multiplex PCR assays and conventional techniques for the diagnostic of respiratory virus infections in children admitted to hospital with an acute respiratory illness Use of monoclonal antibodies for rapid diagnosis of respiratory viruses in a community hospital Viral pathogens of acute lower respiratory tract infection in China Rapid detection of respiratory picornaviruses in nasopharyngeal aspirates by immunofluorescence assay Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children Ten years' experience with year-round active surveillance of up to 19 respiratory pathogens in children Epidemiology of viral infections and evaluation of the potential benefit of OM-85 BV on the virologic status of children attending day-care centers Human rhinoviruses: the cold wars resume Rhinovirus associated with severe lower respiratory tract infections in children Human picornavirus and coronavirus RNA in nasopharynx of children without concurrent respiratory symptoms Frequency of detection of picornaviruses and seven other respiratory pathogens in infants Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response Respiratory syncytial virus, human bocavirus and rhinovirus bronchiolitis in infants Two-year periodicity of respiratory syncytial virus epidemics in Switzerland Monto AS: Epidemiology of influenza Biennial spring activity of human metapneumovirus in Austria Human metapneumovirus infections-biannual epidemics and clinical findings in children in the region of Basel, Switzerland Epidemiologic characteristics and seasonal distribution of human metapneumovirus infections in five epidemic seasons in Prospective study of human metapneumovirus detection in clinical samples by use of light diagnostics direct immunofluorescence reagent and real-time PCR We gratefully acknowledge the technical support of the staff of our Virology Laboratory. key: cord-336975-28mtmw2z authors: Sadeghi, Christine D; Aebi, Christoph; Gorgievski-Hrisoho, Meri; Mühlemann, Kathrin; Barbani, Maria Teresa title: Twelve years' detection of respiratory viruses by immunofluorescence in hospitalised children: impact of the introduction of a new respiratory picornavirus assay date: 2011-02-07 journal: BMC Infect Dis DOI: 10.1186/1471-2334-11-41 sha: doc_id: 336975 cord_uid: 28mtmw2z BACKGROUND: Direct immunofluorescence assays (DFA) are a rapid and inexpensive method for the detection of respiratory viruses and may therefore be used for surveillance.
- keywords: acute; assays; children; clinical; common; detection; dfa; disease; epidemiological; figure; high; hmpv; hospital; human; immunofluorescence; infections; influenza; lower; manuscript; metapneumovirus; methods; pathogens; pcr; picornaviruses; positive; rapid; rate; respiratory; results; rsv; samples; studies; study; syncytial; time; tract; viral; winter; years
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- cord-337028-8fh4pe3i
- author: Reyes, Leticia
- title: Different inflammatory responses are associated with Ureaplasma parvum-induced UTI and urolith formation
- date: 2009-01-26
- words: 5825
- flesch: 43
- summary: This may be reflecting a more balanced immune response than what is seen in U. parvum positive animals, and we suggest that this balanced response may be critical to resolution of infection and prevention of severe disease. The first cluster identified in the negative group included IL-2, IL-4, IL-10, and TNF-α; these cytokines were notable as they were not part of the cytokine cluster groupings of U. parvum infected animals.
- keywords: 10b; analysis; animals; arrow; asymptomatic; bladder; broth; cells; cfu; clinical; complicated; control; culture; cytokine; data; degree; disease; dose; epithelial; extensive; f344; figure; formation; group; host; hyperplasia; ifn; il-1β; immune; infected; infection; inflammation; inflammatory; inoculation; inoculum; kidney; lesions; log; macrophages; negative; panel; parvum; positive; profile; rats; renal; response; score; significant; sterile; strain; struvite; study; tissue; tract; u. parvum; ureaplasma; urinary; urine; uroepithelial; uroliths; uti
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- cord-338054-n2r4pzan
- author: Lau, Joseph TF
- title: Anticipated and current preventive behaviors in response to an anticipated human-to-human H5N1 epidemic in the Hong Kong Chinese general population
- date: 2007-03-15
- words: 3848
- flesch: 42
- summary: key: cord-338054-n2r4pzan authors: Lau, Joseph TF; Kim, Jean H; Tsui, Hi Yi; Griffiths, Sian title: Anticipated and current preventive behaviors in response to an anticipated human-to-human H5N1 epidemic in the Hong Kong Chinese general population date: 2007-03-15 journal: BMC Infect Dis DOI: 10.1186/1471-2334-7-18 sha: doc_id: 338054 cord_uid: n2r4pzan BACKGROUND: A random, anonymous, cross-sectional telephone survey of 503 Hong Kong Chinese adults.
- keywords: anticipated; associated; avian; behaviors; efficacy; epidemic; face; family; fatality; general; h5n1; handwashing; health; higher; hong; hong kong; human; human h5n1; ili; influenza; kong; mask; measures; outbreak; population; poultry; preventive; public; quarantine; rate; reported; respondents; responses; sars; self; significant; study; table; transmission; use; variables; virus
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- cord-341347-nzptmdbe
- author: Neske, Florian
- title: High prevalence of antibodies against polyomavirus WU, polyomavirus KI, and human bocavirus in German blood donors
- date: 2010-07-20
- words: 3363
- flesch: 52
- summary: Elucidation of the clinical relevance of HBoV has been difficult because of a high co-infection rate of HBoV DNA positive samples with other respiratory viruses. As to HBoV, the adult seroprevalence of 76% in our study is slightly lower than in previous studies from Japan, the United States, and Germany, which reported HBoV IgG antibody prevalence of 94%, 86%, and 94%, respectively [15, 17, 19] .
- keywords: acute; adults; age; antibodies; antibody; assays; baculoviruses; blood; bocavirus; cells; children; dna; donors; hbov; healthy; high; human; ifa; igg; infection; invitrogen; jcv; kipyv; median; plasma; polyomaviruses; positive; primary; proteins; rates; recombinant; respiratory; results; samples; serological; seropositivity; seroprevalence; sf9; studies; study; tract; uninfected; virus; viruses; vp1; vp2; wupyv; years
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- cord-341818-mm3d4jkh
- author: Ying, Mingliang
- title: COVID-19 with acute cholecystitis: a case report
- date: 2020-06-22
- words: 1713
- flesch: 52
- summary: PTGD is useful for acute cholecystitis in COVID-19 patients. It was difficult to identify the cause of acute cholecystitis in COVID-19 patients by abdominal CT imaging.
- keywords: abdominal; acute; bile; case; chest; china; cholecystitis; coronavirus; course; covid-19; day; gallbladder; ggos; hospitalization; normal; novel; nucleic; pain; patient; pcr; pneumonia; ptgd; right; study; time
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- cord-342210-r8vxz5vu
- author: Mukherjee, Pranab K.
- title: Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections
- date: 2017-01-14
- words: 4859
- flesch: 43
- summary: Subjectlevel characteristics were summarized per study group, age, gender, prior influenza vaccine status and medications taken for symptom relief. Healthy adults (18–45 years of age) were randomized into ARMS-I or placebo group (50 subjects each).
- keywords: acceptability; active; active group; additional; adults; analysis; arms; barrier; clinical; cough; daily; data; days; diaries; double; duration; effect; effectiveness; events; formulation; frequency; group; host; individuals; infections; influenza; medical; nose; novel; number; oral; participants; placebo; placebo group; prevention; product; protocol; randomized; related; respiratory; safety; severity; sore; study; subject; surveys; symptoms; throat; tract; treatment; trial; upper; uris; use; vaccine; viral; virus; visits
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- cord-342250-x5bzrpcu
- author: Faires, Meredith C
- title: The use of the temporal scan statistic to detect methicillin-resistant Staphylococcus aureus clusters in a community hospital
- date: 2014-07-08
- words: 6872
- flesch: 42
- summary: The objectives of this study were to investigate the utility of the temporal scan statistic for detecting MRSA clusters, validate clusters using molecular techniques and hospital records, and determine significant differences in the rate of MRSA cases using regression models. MRSA clusters were investigated using a retrospective temporal scan statistic.
- keywords: admission; analysis; antimicrobial; aureus; cases; clusters; control; data; days; detection; different; duration; events; facility; february; healthcare; hospital; identification; incidence; increase; independent; infection; internal; investigation; ipc; isolates; laboratory; level; march; medicine; methicillin; model; molecular; months; mrsa; mrsa cases; mrsa clusters; negative; number; outbreaks; patient; period; personnel; population; rate; resistant; results; risk; scan; scan statistic; service; significant; spa; spa type; specific; staphylococcus; statistic; strains; study; surgery; surveillance; t002; temporal; temporal scan; test; time; transmission; type; typing; variables; ward; window; years
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- cord-344770-aoi42xq4
- author: Bialasiewicz, Seweryn
- title: Detection of a divergent Parainfluenza 4 virus in an adult patient with influenza like illness using next-generation sequencing
- date: 2014-05-19
- words: 2704
- flesch: 43
- summary: PCR primers used to amplify and sequence PIV4 strain QLD-01. These findings further support a possible role for Parainfluenza 4 in the aetiology of adult respiratory disease within the community setting, and highlight the caution needed to be used in designing PCR assays from limited sequence information or in using proprietary commercial PCR assays.
- keywords: additional; adult; analyses; assays; available; axis; children; clinical; coding; community; detection; divergent; file; genome; human; illness; infections; information; isolate; manuscript; mismatches; novel; parainfluenza; pcr; piv4; primer; qld-01; reads; recombination; reference; research; respiratory; samples; sequence; sequencing; similarity; skpiv4; strain; study; subtype; tract; variant; viral; virus; viruses; window
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- cord-345046-str19r9a
- author: Al Ghamdi, Mohammed
- title: Treatment outcomes for patients with Middle Eastern Respiratory Syndrome Coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia
- date: 2016-04-21
- words: 3441
- flesch: 44
- summary: Hospital outbreak of Middle East respiratory syndrome coronavirus State of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Humans Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection Jordan MERS-CoV Investigation Team. The severe acute respiratory syndrome Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Patient with new strain of coronavirus is treated in intensive care at London hospital Latest outbreak news from ProMED-mail: novel coronavirus -Middle East Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group WHO summary Family cluster of Middle East respiratory syndrome coronavirus infections KSA MERS-CoV Investigation Team.
- keywords: acute; alpha; analysis; arabia; beta; care; cases; cell; clinical; cohort; collection; combination; coronavirus; cov; data; disease; east; ecmo; efficacy; failure; health; hospital; human; icu; illness; infection; interferon; known; manuscript; mers; middle; mofetil; mortality; mycophenolate; novel; orf; outcomes; patients; pcr; renal; respiratory; results; retrospective; ribavirin; saudi; severe; severity; study; survival; syndrome; treatment
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- cord-345854-f0dq94j1
- author: Chong, Wai Po
- title: The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome
- date: 2006-05-04
- words: 1774
- flesch: 46
- summary: Severe acute respiratory syndrome (SARS) is an infectious disease caused by SARS coronavirus [1] with >8000 cases and 774 deaths reported in 2003 The IFN-γ +874A allele was overrepresented in SARS patients (83.1%) when compared with the controls (66.3%) (P < 0.001).
- keywords: +874a; acute; allele; antiviral; controls; coronavirus; cytokine; expression; factor; gene; ifn; il-10; important; infection; inflammatory; patients; polymorphisms; production; regulation; respiratory; response; role; sars; severe; snps; study; susceptibility; syndrome; tnf
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- cord-346669-7n75m669
- author: Wang, Shixin
- title: Roles of TNF-α gene polymorphisms in the occurrence and progress of SARS-Cov infection: A case-control study
- date: 2008-02-29
- words: 3816
- flesch: 45
- summary: Cured SARS patients with interstitial lung fibrosis were diagnosed by respiratory experts according to CT results following the standard proposal for therapy and diagnosis of SARS patients issued by Chinese Ministry of Health in 2004 After discharging from hospital, interstitial lung fibrosis was observed in SARS patients.
- keywords: acute; analysis; association; care; case; control; cov; cytokine; differences; effect; factor; femoral; femoral head; fibrosis; gene; genetic; genotype; head; head necrosis; health; hla; hormone; human; individual; infection; interstitial; interstitial lung; lung; lung fibrosis; necrosis; non; occurrence; patients; polymorphisms; population; promoter; pulmonary; rate; region; respiratory; results; risk; sars; sars patients; severe; studies; study; syndrome; tnf; tumor; workers
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- cord-348802-3f8kmw31
- author: Tang, Jialiang
- title: Diversity of upper respiratory tract infections and prevalence of Streptococcus pneumoniae colonization among patients with fever and flu-like symptoms
- date: 2019-01-07
- words: 4995
- flesch: 37
- summary: Evidence from a Seroepidemiology survey in Zhejiang, an Eastern Province of China Epidemiological features of pertussis resurgence based on community populations with high vaccination coverage in China Seroprevalence of pertussis in China: need to improve vaccination strategies Prolonged afebrile nonproductive cough illnesses in American soldiers in Korea: a serological search for causation Clinical and laboratory features of pertussis in hospitalized infants with confirmed versus probable pertussis cases Infectious diseases Society of a: clinical practice guideline for the diagnosis and management of group a streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America Upper airway viruses and bacteria in urban aboriginal and Torres Strait islander children in Brisbane, Australia: a cross-sectional study Seasonal variation of respiratory pathogen colonization in asymptomatic health care professionals: a singlecenter, cross-sectional, 2-season observational study Carriage of mycoplasma pneumoniae in the upper respiratory tract of symptomatic and asymptomatic children: an observational study Guidelines for the use of antibiotics in acute upper respiratory tract infections We would like to acknowledge Linlin Pan, Shifang Tao, Yifang Wang, Yuanyuan Cai, Weifeng Chu, and Lin Zheng from IngeniGen XunMinKang Biotechnology Inc., Shaoxing, for providing technical support in this study. S. pneumoniae colonization was found in 8.0% of the cases but most of them had low bacterial density (Mean = 3.9 log cfu/ml).
- keywords: age; antibiotics; bacterial; cases; cfu; children; china; colonization; colonization frequency; common; community; density; detection; difference; fever; fig; flu; flua; frequency; groups; high; higher; hrv; infections; january; like; lower; months; nasopharyngeal; overall; pathogens; patients; pcr; pertussis; pneumoniae; pneumoniae colonization; positive; prevalence; relationship; respiratory; rsv; samples; shaoxing; significant; streptococcus; study; symptoms; table; test; tract; upper; urti; urti pathogens; viral; viruses; years
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- cord-349238-qfvm883x
- author: Maponga, Brian A
- title: Risk factors for contracting watery diarrhoea in Kadoma City, Zimbabwe, 2011: a case control study
- date: 2013-12-02
- words: 3457
- flesch: 59
- summary: Water samples that were found with zero colonies after incubation for 24 hours were considered satisfactory. [AOR = 0.44; 95% CI (0.24-0.82)]; using municipal water [AOR = 0.38; 95% CI (0.18-0.80)]; using aqua tablets, [AOR = 0.49; 95% CI (0.26–0.94)] and; storing water in closed containers, [AOR = 0.24; 95% CI (0.07–0.0.83).
- keywords: analysis; aor; breast; caregivers; cases; children; city; coli; contamination; contracting; controls; data; days; diarrhoea; escherichia; exclusive; factors; feeding; hand; health; home; kadoma; municipal; october; old; outbreak; people; protective; rate; results; rimuka; risk; rotavirus; samples; september; specimens; study; tablets; threshold; township; treatment; use; washing; water; week; years; years old; zimbabwe
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- cord-349905-jniqriu6
- author: Xu, Xinyin
- title: Should we remain hopeful? The key 8 weeks: spatiotemporal epidemic characteristics of COVID-19 in Sichuan Province and its comparative analysis with other provinces in China and global epidemic trends
- date: 2020-11-05
- words: 5394
- flesch: 61
- summary: The top five cities with confirmed case numbers were Chengdu, Ganzi, Dazhou, Nanchong, and Guang'an. The number of confirmed cases, daily growth, incidence and length of time from the first reported case to the end of the local cases (i.e., non-overseas imported cases) were compared by spatial (geographical) and temporal classification and visualization of the development and changes of the epidemic situation by layers through maps.
- keywords: analysis; average; cases; change; china; cities; city; coefficient; commission; confirmed; control; coronavirus; countries; covid-19; daily; data; days; different; disease; epidemic; february; fig; growth; health; hubei; incidence; increase; information; january; length; level; local; lockdown; march; number; peak; population; prevention; province; rapid; region; report; rise; sichuan; sichuan province; situation; spatial; stage; study; time; total; value; weeks; wuhan
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- cord-350949-ystkjdwk
- author: Gao, Yi-jie
- title: Clinical features and outcomes of pregnant women with COVID-19: a systematic review and meta-analysis
- date: 2020-08-03
- words: 4524
- flesch: 48
- summary: The incidences of fever, cough and positive CT findings in pregnant women with COVID-19 are less than those in the normal population with COVID-19, but the rate of preterm labor is higher among pregnant with COVID-19 than among normal pregnant women. The rate of preterm labor in normal pregnant women worldwide who are healthy and not infected with any virus is lower than that in pregnant women with COVID-19.
- keywords: analysis; articles; case; characteristics; china; clinical; coronavirus; cough; cov-2; covid-19; data; death; disease; features; fever; findings; heterogeneity; incidence; infected; infection; labor; literature; lower; meta; neonatal; non; novel; outcomes; patients; pneumonia; population; positive; pregnancy; pregnant; pregnant women; preterm; publication; quality; rate; results; review; sars; section; series; severe; studies; study; transmission; vertical; women
- versions: original; plain text
- cord-351126-d6lfktf9
- author: Kofman, Aaron D.
- title: A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report
- date: 2020-09-29
- words: 1935
- flesch: 41
- summary: key: cord-351126-d6lfktf9 authors: Kofman, Aaron D.; Sizemore, Emma K.; Detelich, Joshua F.; Albrecht, Benjamin; Piantadosi, Anne L. title: A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report date: 2020-09-29 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05439-z sha: doc_id: 351126 cord_uid: d6lfktf9 BACKGROUND: A healthy 25-year-old woman developed COVID-19 disease with clinical characteristics resembling Multisystem Inflammatory Syndrome in Children (MIS-C), a rare form of COVID-19 described primarily in children under 21 years of age. Authors' contributions AK and AP analyzed and interpreted the patient data regarding clinical infectious diseases presentation.
- keywords: acute; adults; aspirin; cardiac; case; children; clinical; concern; covid-19; day; disease; dysfunction; evidence; features; hospital; illness; inflammatory; involvement; ivig; kawasaki; like; mild; mis; multisystem; patient; pediatric; presentation; report; respiratory; sars; severe; shock; symptoms; syndrome; treatment; young
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- cord-354690-ywb9krdp
- author: Barr, Margo
- title: Pandemic influenza in Australia: Using telephone surveys to measure perceptions of threat and willingness to comply
- date: 2008-09-15
- words: 3842
- flesch: 45
- summary: key: cord-354690-ywb9krdp authors: Barr, Margo; Raphael, Beverley; Taylor, Melanie; Stevens, Garry; Jorm, Louisa; Giffin, Michael; Lujic, Sanja title: Pandemic influenza in Australia: Using telephone surveys to measure perceptions of threat and willingness to comply date: 2008-09-15 journal: BMC Infect Dis DOI: 10.1186/1471-2334-8-117 sha: doc_id: 354690 cord_uid: ywb9krdp BACKGROUND: Baseline data is necessary for monitoring how a population perceives the threat of pandemic influenza, and perceives how it would behave in the event of pandemic influenza. When the indicators for pandemic influenza likelihood, concern for self and family and changed life were combined, as shown in Figure 1 , the greatest proportion of the population (41.3%) thought pandemic influenza was unlikely to occur, would not be concerned for themselves or their family, and had not changed the way they lived their life because of the possibility of pandemic influenza.
- keywords: avian; behaviours; compliance; data; event; face; family; field; h5n1; health; higher; hong; indicators; influenza; isolated; kong; level; life; likely; mask; new; outbreak; pandemic; pandemic influenza; perception; population; protective; psychological; public; questions; respondents; response; risk; sars; self; south; study; survey; test; threat; vaccination; wales; willing
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- cord-354827-ipg1vwmv
- author: Baker, Stephen
- title: Searching for the elusive typhoid diagnostic
- date: 2010-03-05
- words: 5148
- flesch: 42
- summary: Could S. Typhi culture be further optimized, by taking advantage of some atypical biochemical properties of the organism? The methodology is dependent on agglutination; S. Typhi cells are used to detect antibodies in blood.
- keywords: antibodies; antigens; approach; area; assay; available; bacteria; blood; bone; burden; carriers; cause; cells; clinical; common; cost; countries; cross; culture; current; data; detection; diagnosis; disease; dna; e.g.; endemic; enterica; facilities; fever; figure; gene; genome; high; host; immune; infection; lack; limitations; limited; low; marrow; microbiological; negative; new; novel; number; organism; paratyphi; pathogen; pathogenesis; patients; pcr; positive; potential; rapid; real; response; s. typhi; salmonella; samples; sensitivity; serovar; significant; simple; specific; specificity; studies; system; systemic; test; time; typhi; typhoid; urine; variation; worth
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- cord-355309-nr8fwc8q
- author: Porten, Klaudia
- title: A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany
- date: 2006-10-06
- words: 5340
- flesch: 55
- summary: Seventeen (85%) of 20 cases indicated that they had seen the cow (that also was on display at the market next to the sheep) compared to 7 (32%) of Geographical location of Q fever outbreak cases notified to the statutory surveillance system Figure 3 Geographical location of Q fever outbreak cases notified to the statutory surveillance system. A total of 299 reported Q fever cases was linked to this outbreak.
- keywords: acute; adults; animals; anti; attack; burnetii; cases; ccs2; children; clinical; close; cohort; controls; data; days; direction; disease; distance; factors; farmers; fever; figure; flocks; germany; health; infection; interviews; investigation; laboratory; large; local; market; meters; number; outbreak; patients; pen; persons; phase; positive; pregnant; proportion; q fever; rate; risk; second; sheep; sheep pen; soest; source; stands; study; system; vendors; visitors; wind
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- cord-356349-ey5vnddu
- author: Fusco, Francesco M
- title: Infection control management of patients with suspected highly infectious diseases in emergency departments: data from a survey in 41 facilities in 14 European countries
- date: 2012-01-28
- words: 4041
- flesch: 39
- summary: Most partners are clinicians working in isolation facilities designated for referral of patients with HIDs. As the main target of the project were isolation facilities for HID cases, the EDs and MADs surveyed are operating within, or in the same hospital compound, as a regional/national reference hospital for infectious diseases: thus, we believe that the occurrence of HIDs is more likely in these facilities, due to referral of suspected patients from other medical facilities or to selfreferral of patient returning from endemic countries for HID.
- keywords: adequate; appropriate; areas; availability; available; care; cases; centres; checklists; control; countries; data; department; diseases; early; eds; emergency; euronhid; european; evaluation; facilities; features; health; hids; hospital; infectious; infectious diseases; isolation; level; logistic; mads; management; medical; national; network; order; pandemic; partners; patients; preparedness; procedures; project; recognition; referral; rooms; specific; staff; study; survey; transmission; triage
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