id	sid	tid	token	lemma	pos
brainmatters-1083	1	1	brain	brain	NOUN
brainmatters-1083	1	2	matters	matter	NOUN
brainmatters-1083	1	3	vol	vol	NOUN
brainmatters-1083	1	4	.	.	PROPN
brainmatters-1083	1	5	8	8	NUM
brainmatters-1083	2	1	no	no	NOUN
brainmatters-1083	2	2	.	.	NOUN
brainmatters-1083	2	3	2	2	NUM
brainmatters-1083	2	4	abstract	abstract	ADJ
brainmatters-1083	2	5	human	human	ADJ
brainmatters-1083	2	6	leukocyte	leukocyte	NOUN
brainmatters-1083	2	7	antigens	antigen	NOUN
brainmatters-1083	2	8	(	(	PUNCT
brainmatters-1083	2	9	hla	hla	NOUN
brainmatters-1083	2	10	)	)	PUNCT
brainmatters-1083	2	11	are	be	AUX
brainmatters-1083	2	12	significant	significant	ADJ
brainmatters-1083	2	13	components	component	NOUN
brainmatters-1083	2	14	of	of	ADP
brainmatters-1083	2	15	the	the	DET
brainmatters-1083	2	16	human	human	ADJ
brainmatters-1083	2	17	immune	immune	ADJ
brainmatters-1083	2	18	system	system	NOUN
brainmatters-1083	2	19	responsible	responsible	ADJ
brainmatters-1083	2	20	for	for	ADP
brainmatters-1083	2	21	autoimmunity	autoimmunity	NOUN
brainmatters-1083	2	22	.	.	PUNCT
brainmatters-1083	3	1	these	these	DET
brainmatters-1083	3	2	genes	gene	NOUN
brainmatters-1083	3	3	are	be	AUX
brainmatters-1083	3	4	located	locate	VERB
brainmatters-1083	3	5	on	on	ADP
brainmatters-1083	3	6	chromosome	chromosome	NOUN
brainmatters-1083	3	7	6	6	NUM
brainmatters-1083	3	8	and	and	CCONJ
brainmatters-1083	3	9	encode	encode	ADJ
brainmatters-1083	3	10	for	for	ADP
brainmatters-1083	3	11	proteins	protein	NOUN
brainmatters-1083	3	12	that	that	PRON
brainmatters-1083	3	13	assist	assist	VERB
brainmatters-1083	3	14	the	the	DET
brainmatters-1083	3	15	body	body	NOUN
brainmatters-1083	3	16	in	in	ADP
brainmatters-1083	3	17	fighting	fight	VERB
brainmatters-1083	3	18	against	against	ADP
brainmatters-1083	3	19	foreign	foreign	ADJ
brainmatters-1083	3	20	invaders	invader	NOUN
brainmatters-1083	3	21	.	.	PUNCT
brainmatters-1083	4	1	however	however	ADV
brainmatters-1083	4	2	,	,	PUNCT
brainmatters-1083	4	3	hla	hla	PROPN
brainmatters-1083	4	4	may	may	AUX
brainmatters-1083	4	5	have	have	VERB
brainmatters-1083	4	6	the	the	DET
brainmatters-1083	4	7	potential	potential	NOUN
brainmatters-1083	4	8	to	to	PART
brainmatters-1083	4	9	induce	induce	VERB
brainmatters-1083	4	10	varying	vary	VERB
brainmatters-1083	4	11	degrees	degree	NOUN
brainmatters-1083	4	12	of	of	ADP
brainmatters-1083	4	13	brain	brain	NOUN
brainmatters-1083	4	14	atrophy	atrophy	NOUN
brainmatters-1083	4	15	(	(	PUNCT
brainmatters-1083	4	16	ba	ba	NOUN
brainmatters-1083	4	17	)	)	PUNCT
brainmatters-1083	4	18	and	and	CCONJ
brainmatters-1083	4	19	multiple	multiple	ADJ
brainmatters-1083	4	20	sclerosis	sclerosis	NOUN
brainmatters-1083	4	21	(	(	PUNCT
brainmatters-1083	4	22	ms	ms	NOUN
brainmatters-1083	4	23	)	)	PUNCT
brainmatters-1083	4	24	,	,	PUNCT
brainmatters-1083	4	25	both	both	PRON
brainmatters-1083	4	26	of	of	ADP
brainmatters-1083	4	27	which	which	PRON
brainmatters-1083	4	28	are	be	AUX
brainmatters-1083	4	29	neurodegenerative	neurodegenerative	ADJ
brainmatters-1083	4	30	disorders	disorder	NOUN
brainmatters-1083	4	31	.	.	PUNCT
brainmatters-1083	5	1	examining	examine	VERB
brainmatters-1083	5	2	the	the	DET
brainmatters-1083	5	3	protective	protective	ADJ
brainmatters-1083	5	4	and	and	CCONJ
brainmatters-1083	5	5	aggravating	aggravating	ADJ
brainmatters-1083	5	6	effects	effect	NOUN
brainmatters-1083	5	7	of	of	ADP
brainmatters-1083	5	8	hla	hla	NOUN
brainmatters-1083	5	9	on	on	ADP
brainmatters-1083	5	10	these	these	DET
brainmatters-1083	5	11	neurological	neurological	ADJ
brainmatters-1083	5	12	disorders	disorder	NOUN
brainmatters-1083	5	13	,	,	PUNCT
brainmatters-1083	5	14	as	as	ADV
brainmatters-1083	5	15	well	well	ADV
brainmatters-1083	5	16	as	as	ADP
brainmatters-1083	5	17	potential	potential	ADJ
brainmatters-1083	5	18	preventive	preventive	ADJ
brainmatters-1083	5	19	measures	measure	NOUN
brainmatters-1083	5	20	that	that	PRON
brainmatters-1083	5	21	could	could	AUX
brainmatters-1083	5	22	be	be	AUX
brainmatters-1083	5	23	implemented	implement	VERB
brainmatters-1083	5	24	through	through	ADP
brainmatters-1083	5	25	hla	hla	PROPN
brainmatters-1083	5	26	,	,	PUNCT
brainmatters-1083	5	27	may	may	AUX
brainmatters-1083	5	28	prove	prove	VERB
brainmatters-1083	5	29	to	to	PART
brainmatters-1083	5	30	have	have	VERB
brainmatters-1083	5	31	significant	significant	ADJ
brainmatters-1083	5	32	effects	effect	NOUN
brainmatters-1083	5	33	on	on	ADP
brainmatters-1083	5	34	the	the	DET
brainmatters-1083	5	35	approach	approach	NOUN
brainmatters-1083	5	36	to	to	ADP
brainmatters-1083	5	37	ba	ba	PROPN
brainmatters-1083	5	38	and	and	CCONJ
brainmatters-1083	5	39	ms	ms	PROPN
brainmatters-1083	5	40	.	.	PROPN
brainmatters-1083	6	1	the	the	DET
brainmatters-1083	6	2	role	role	NOUN
brainmatters-1083	6	3	of	of	ADP
brainmatters-1083	6	4	human	human	ADJ
brainmatters-1083	6	5	leukocyte	leukocyte	NOUN
brainmatters-1083	6	6	antigens	antigen	NOUN
brainmatters-1083	6	7	in	in	ADP
brainmatters-1083	6	8	multiple	multiple	ADJ
brainmatters-1083	6	9	sclerosis	sclerosis	NOUN
brainmatters-1083	6	10	and	and	CCONJ
brainmatters-1083	6	11	brain	brain	NOUN
brainmatters-1083	6	12	atrophy	atrophy	NOUN
brainmatters-1083	6	13	written	write	VERB
brainmatters-1083	6	14	by	by	ADP
brainmatters-1083	6	15	tanisha	tanisha	PROPN
brainmatters-1083	6	16	mandal	mandal	PROPN
brainmatters-1083	6	17	when	when	SCONJ
brainmatters-1083	6	18	the	the	DET
brainmatters-1083	6	19	loss	loss	NOUN
brainmatters-1083	6	20	of	of	ADP
brainmatters-1083	6	21	connection	connection	NOUN
brainmatters-1083	6	22	is	be	AUX
brainmatters-1083	6	23	so	so	ADV
brainmatters-1083	6	24	great	great	ADJ
brainmatters-1083	6	25	that	that	SCONJ
brainmatters-1083	6	26	it	it	PRON
brainmatters-1083	6	27	can	can	AUX
brainmatters-1083	6	28	be	be	AUX
brainmatters-1083	6	29	considered	consider	VERB
brainmatters-1083	6	30	abnormal	abnormal	ADJ
brainmatters-1083	6	31	.	.	PUNCT
brainmatters-1083	7	1	due	due	ADP
brainmatters-1083	7	2	to	to	ADP
brainmatters-1083	7	3	the	the	DET
brainmatters-1083	7	4	fact	fact	NOUN
brainmatters-1083	7	5	that	that	SCONJ
brainmatters-1083	7	6	ms	ms	PROPN
brainmatters-1083	7	7	is	be	AUX
brainmatters-1083	7	8	an	an	DET
brainmatters-1083	7	9	autoimmune	autoimmune	ADJ
brainmatters-1083	7	10	disorder	disorder	NOUN
brainmatters-1083	7	11	,	,	PUNCT
brainmatters-1083	7	12	it	it	PRON
brainmatters-1083	7	13	can	can	AUX
brainmatters-1083	7	14	be	be	AUX
brainmatters-1083	7	15	linked	link	VERB
brainmatters-1083	7	16	to	to	ADP
brainmatters-1083	7	17	human	human	ADJ
brainmatters-1083	7	18	leukocyte	leukocyte	NOUN
brainmatters-1083	7	19	antigens	antigen	NOUN
brainmatters-1083	7	20	.	.	PUNCT
brainmatters-1083	8	1	human	human	ADJ
brainmatters-1083	8	2	leukocyte	leukocyte	NOUN
brainmatters-1083	8	3	antigens	antigen	NOUN
brainmatters-1083	8	4	,	,	PUNCT
brainmatters-1083	8	5	or	or	CCONJ
brainmatters-1083	8	6	hla	hla	PROPN
brainmatters-1083	8	7	for	for	ADP
brainmatters-1083	8	8	short	short	ADJ
brainmatters-1083	8	9	,	,	PUNCT
brainmatters-1083	8	10	are	be	AUX
brainmatters-1083	8	11	found	find	VERB
brainmatters-1083	8	12	on	on	ADP
brainmatters-1083	8	13	chromosome	chromosome	NOUN
brainmatters-1083	8	14	6	6	NUM
brainmatters-1083	8	15	and	and	CCONJ
brainmatters-1083	8	16	encode	encode	ADJ
brainmatters-1083	8	17	for	for	ADP
brainmatters-1083	8	18	proteins	protein	NOUN
brainmatters-1083	8	19	that	that	PRON
brainmatters-1083	8	20	present	present	ADJ
brainmatters-1083	8	21	as	as	ADP
brainmatters-1083	8	22	antigenic	antigenic	ADJ
brainmatters-1083	8	23	peptides	peptide	NOUN
brainmatters-1083	8	24	on	on	ADP
brainmatters-1083	8	25	t	t	NOUN
brainmatters-1083	8	26	cells	cell	NOUN
brainmatters-1083	8	27	.	.	PUNCT
brainmatters-1083	9	1	this	this	PRON
brainmatters-1083	9	2	means	mean	VERB
brainmatters-1083	9	3	that	that	SCONJ
brainmatters-1083	9	4	ms	ms	PROPN
brainmatters-1083	9	5	is	be	AUX
brainmatters-1083	9	6	a	a	DET
brainmatters-1083	9	7	t	t	NOUN
brainmatters-1083	9	8	-	-	PUNCT
brainmatters-1083	9	9	cell	cell	NOUN
brainmatters-1083	9	10	-	-	PUNCT
brainmatters-1083	9	11	mediated	mediate	VERB
brainmatters-1083	9	12	autoimmune	autoimmune	ADJ
brainmatters-1083	9	13	disorder	disorder	NOUN
brainmatters-1083	9	14	.	.	PUNCT
brainmatters-1083	10	1	hla	hla	PROPN
brainmatters-1083	10	2	-dr	-dr	NOUN
brainmatters-1083	10	3	antigens	antigen	NOUN
brainmatters-1083	10	4	specifically	specifically	ADV
brainmatters-1083	10	5	are	be	AUX
brainmatters-1083	10	6	membrane	membrane	ADJ
brainmatters-1083	10	7	heterodimeric	heterodimeric	ADJ
brainmatters-1083	10	8	glycoproteins	glycoprotein	NOUN
brainmatters-1083	10	9	,	,	PUNCT
brainmatters-1083	10	10	which	which	PRON
brainmatters-1083	10	11	means	mean	VERB
brainmatters-1083	10	12	that	that	SCONJ
brainmatters-1083	10	13	they	they	PRON
brainmatters-1083	10	14	consist	consist	VERB
brainmatters-1083	10	15	of	of	ADP
brainmatters-1083	10	16	proteins	protein	NOUN
brainmatters-1083	10	17	that	that	PRON
brainmatters-1083	10	18	are	be	AUX
brainmatters-1083	10	19	found	find	VERB
brainmatters-1083	10	20	in	in	ADP
brainmatters-1083	10	21	cell	cell	NOUN
brainmatters-1083	10	22	membranes	membrane	NOUN
brainmatters-1083	10	23	,	,	PUNCT
brainmatters-1083	10	24	and	and	CCONJ
brainmatters-1083	10	25	often	often	ADV
brainmatters-1083	10	26	play	play	VERB
brainmatters-1083	10	27	a	a	DET
brainmatters-1083	10	28	role	role	NOUN
brainmatters-1083	10	29	in	in	ADP
brainmatters-1083	10	30	communication	communication	NOUN
brainmatters-1083	10	31	and	and	CCONJ
brainmatters-1083	10	32	signaling	signal	VERB
brainmatters-1083	10	33	(	(	PUNCT
brainmatters-1083	10	34	scholz	scholz	NOUN
brainmatters-1083	10	35	,	,	PUNCT
brainmatters-1083	10	36	e.	e.	PROPN
brainmatters-1083	10	37	m	m	PROPN
brainmatters-1083	10	38	,	,	PUNCT
brainmatters-1083	10	39	marcilla	marcilla	NOUN
brainmatters-1083	10	40	,	,	PUNCT
brainmatters-1083	10	41	m	m	PROPN
brainmatters-1083	10	42	,	,	PUNCT
brainmatters-1083	10	43	daura	daura	NOUN
brainmatters-1083	10	44	,	,	PUNCT
brainmatters-1083	10	45	x	x	PRON
brainmatters-1083	10	46	,	,	PUNCT
brainmatters-1083	10	47	et	et	PROPN
brainmatters-1083	10	48	al	al	PROPN
brainmatters-1083	10	49	.	.	PROPN
brainmatters-1083	10	50	,	,	PUNCT
brainmatters-1083	10	51	2017	2017	NUM
brainmatters-1083	10	52	)	)	PUNCT
brainmatters-1083	10	53	.	.	PUNCT
brainmatters-1083	11	1	in	in	ADP
brainmatters-1083	11	2	the	the	DET
brainmatters-1083	11	3	case	case	NOUN
brainmatters-1083	11	4	of	of	ADP
brainmatters-1083	11	5	hla	hla	NOUN
brainmatters-1083	11	6	specifically	specifically	ADV
brainmatters-1083	11	7	,	,	PUNCT
brainmatters-1083	11	8	they	they	PRON
brainmatters-1083	11	9	play	play	VERB
brainmatters-1083	11	10	an	an	DET
brainmatters-1083	11	11	important	important	ADJ
brainmatters-1083	11	12	role	role	NOUN
brainmatters-1083	11	13	in	in	ADP
brainmatters-1083	11	14	the	the	DET
brainmatters-1083	11	15	autoimmune	autoimmune	ADJ
brainmatters-1083	11	16	response	response	NOUN
brainmatters-1083	11	17	system	system	NOUN
brainmatters-1083	11	18	of	of	ADP
brainmatters-1083	11	19	the	the	DET
brainmatters-1083	11	20	human	human	ADJ
brainmatters-1083	11	21	body	body	NOUN
brainmatters-1083	11	22	.	.	PUNCT
brainmatters-1083	12	1	as	as	ADP
brainmatters-1083	12	2	a	a	DET
brainmatters-1083	12	3	result	result	NOUN
brainmatters-1083	12	4	,	,	PUNCT
brainmatters-1083	12	5	many	many	ADJ
brainmatters-1083	12	6	autoimmune	autoimmune	ADJ
brainmatters-1083	12	7	disorders	disorder	NOUN
brainmatters-1083	12	8	are	be	AUX
brainmatters-1083	12	9	caused	cause	VERB
brainmatters-1083	12	10	by	by	ADP
brainmatters-1083	12	11	defects	defect	NOUN
brainmatters-1083	12	12	in	in	ADP
brainmatters-1083	12	13	the	the	DET
brainmatters-1083	12	14	hla	hla	PROPN
brainmatters-1083	12	15	gene	gene	NOUN
brainmatters-1083	12	16	.	.	PUNCT
brainmatters-1083	13	1	after	after	ADP
brainmatters-1083	13	2	extensive	extensive	ADJ
brainmatters-1083	13	3	research	research	NOUN
brainmatters-1083	13	4	,	,	PUNCT
brainmatters-1083	13	5	the	the	DET
brainmatters-1083	13	6	allele	allele	NOUN
brainmatters-1083	13	7	responsible	responsible	ADJ
brainmatters-1083	13	8	for	for	ADP
brainmatters-1083	13	9	this	this	DET
brainmatters-1083	13	10	development	development	NOUN
brainmatters-1083	13	11	has	have	AUX
brainmatters-1083	13	12	been	be	AUX
brainmatters-1083	13	13	narrowed	narrow	VERB
brainmatters-1083	13	14	down	down	ADP
brainmatters-1083	13	15	to	to	ADP
brainmatters-1083	13	16	class	class	PROPN
brainmatters-1083	13	17	ii	ii	PROPN
brainmatters-1083	13	18	hladrb1	hladrb1	PROPN
brainmatters-1083	13	19	*	*	PROPN
brainmatters-1083	13	20	1501	1501	NUM
brainmatters-1083	13	21	(	(	PUNCT
brainmatters-1083	13	22	lorefice	lorefice	NOUN
brainmatters-1083	13	23	l	l	NOUN
brainmatters-1083	13	24	,	,	PUNCT
brainmatters-1083	13	25	fenu	fenu	PROPN
brainmatters-1083	13	26	g	g	NOUN
brainmatters-1083	13	27	,	,	PUNCT
brainmatters-1083	13	28	sardu	sardu	PROPN
brainmatters-1083	13	29	c	c	AUX
brainmatters-1083	13	30	,	,	PUNCT
brainmatters-1083	13	31	et	et	PROPN
brainmatters-1083	13	32	al	al	PROPN
brainmatters-1083	13	33	.	.	PROPN
brainmatters-1083	13	34	,	,	PUNCT
brainmatters-1083	13	35	2019	2019	NUM
brainmatters-1083	13	36	)	)	PUNCT
brainmatters-1083	13	37	.	.	PUNCT
brainmatters-1083	14	1	more	more	ADJ
brainmatters-1083	14	2	research	research	NOUN
brainmatters-1083	14	3	has	have	AUX
brainmatters-1083	14	4	uncovered	uncover	VERB
brainmatters-1083	14	5	that	that	SCONJ
brainmatters-1083	14	6	hla	hla	PROPN
brainmatters-1083	14	7	can	can	AUX
brainmatters-1083	14	8	also	also	ADV
brainmatters-1083	14	9	provide	provide	VERB
brainmatters-1083	14	10	protective	protective	ADJ
brainmatters-1083	14	11	effects	effect	NOUN
brainmatters-1083	14	12	against	against	ADP
brainmatters-1083	14	13	the	the	DET
brainmatters-1083	14	14	demyelination	demyelination	NOUN
brainmatters-1083	14	15	caused	cause	VERB
brainmatters-1083	14	16	by	by	ADP
brainmatters-1083	14	17	ba	ba	PROPN
brainmatters-1083	14	18	and	and	CCONJ
brainmatters-1083	14	19	ms	ms	PROPN
brainmatters-1083	14	20	.	.	PROPN
brainmatters-1083	15	1	this	this	PRON
brainmatters-1083	15	2	is	be	AUX
brainmatters-1083	15	3	due	due	ADJ
brainmatters-1083	15	4	to	to	ADP
brainmatters-1083	15	5	another	another	DET
brainmatters-1083	15	6	class	class	NOUN
brainmatters-1083	15	7	ii	ii	NOUN
brainmatters-1083	15	8	allele	allele	NOUN
brainmatters-1083	15	9	,	,	PUNCT
brainmatters-1083	15	10	specifically	specifically	ADV
brainmatters-1083	15	11	drb1	drb1	PROPN
brainmatters-1083	15	12	*	*	X
brainmatters-1083	15	13	1302	1302	NUM
brainmatters-1083	15	14	,	,	PUNCT
brainmatters-1083	15	15	which	which	PRON
brainmatters-1083	15	16	works	work	VERB
brainmatters-1083	15	17	in	in	ADP
brainmatters-1083	15	18	the	the	DET
brainmatters-1083	15	19	cns	cns	NOUN
brainmatters-1083	15	20	and	and	CCONJ
brainmatters-1083	15	21	has	have	AUX
brainmatters-1083	15	22	been	be	AUX
brainmatters-1083	15	23	shown	show	VERB
brainmatters-1083	15	24	to	to	PART
brainmatters-1083	15	25	prevent	prevent	VERB
brainmatters-1083	15	26	the	the	DET
brainmatters-1083	15	27	rapid	rapid	ADJ
brainmatters-1083	15	28	degeneration	degeneration	NOUN
brainmatters-1083	15	29	of	of	ADP
brainmatters-1083	15	30	neurons	neuron	NOUN
brainmatters-1083	15	31	associated	associate	VERB
brainmatters-1083	15	32	with	with	ADP
brainmatters-1083	15	33	ba	ba	PROPN
brainmatters-1083	15	34	.	.	PUNCT
brainmatters-1083	16	1	class	class	PROPN
brainmatters-1083	16	2	ii	ii	PROPN
brainmatters-1083	16	3	hla	hla	PROPN
brainmatters-1083	16	4	has	have	VERB
brainmatters-1083	16	5	complex	complex	ADJ
brainmatters-1083	16	6	effects	effect	NOUN
brainmatters-1083	16	7	on	on	ADP
brainmatters-1083	16	8	the	the	DET
brainmatters-1083	16	9	cns	cns	NOUN
brainmatters-1083	16	10	,	,	PUNCT
brainmatters-1083	16	11	thus	thus	ADV
brainmatters-1083	16	12	contributing	contribute	VERB
brainmatters-1083	16	13	to	to	ADP
brainmatters-1083	16	14	the	the	DET
brainmatters-1083	16	15	development	development	NOUN
brainmatters-1083	16	16	of	of	ADP
brainmatters-1083	16	17	brain	brain	NOUN
brainmatters-1083	16	18	atrophy	atrophy	NOUN
brainmatters-1083	16	19	and	and	CCONJ
brainmatters-1083	16	20	multiple	multiple	ADJ
brainmatters-1083	16	21	sclerosis	sclerosis	NOUN
brainmatters-1083	16	22	,	,	PUNCT
brainmatters-1083	16	23	with	with	ADP
brainmatters-1083	16	24	different	different	ADJ
brainmatters-1083	16	25	alleles	allele	NOUN
brainmatters-1083	16	26	of	of	ADP
brainmatters-1083	16	27	the	the	DET
brainmatters-1083	16	28	same	same	ADJ
brainmatters-1083	16	29	gene	gene	NOUN
brainmatters-1083	16	30	providing	provide	VERB
brainmatters-1083	16	31	vastly	vastly	ADV
brainmatters-1083	16	32	different	different	ADJ
brainmatters-1083	16	33	outcomes	outcome	NOUN
brainmatters-1083	16	34	.	.	PUNCT
brainmatters-1083	17	1	introduction	introduction	NOUN
brainmatters-1083	17	2	brain	brain	NOUN
brainmatters-1083	17	3	atrophy	atrophy	NOUN
brainmatters-1083	17	4	(	(	PUNCT
brainmatters-1083	17	5	ba	ba	NOUN
brainmatters-1083	17	6	)	)	PUNCT
brainmatters-1083	17	7	is	be	AUX
brainmatters-1083	17	8	a	a	DET
brainmatters-1083	17	9	progressive	progressive	ADJ
brainmatters-1083	17	10	neurodegenerative	neurodegenerative	ADJ
brainmatters-1083	17	11	disorder	disorder	NOUN
brainmatters-1083	17	12	that	that	PRON
brainmatters-1083	17	13	leads	lead	VERB
brainmatters-1083	17	14	to	to	ADP
brainmatters-1083	17	15	neuronal	neuronal	ADJ
brainmatters-1083	17	16	loss	loss	NOUN
brainmatters-1083	17	17	and	and	CCONJ
brainmatters-1083	17	18	connectivity	connectivity	NOUN
brainmatters-1083	17	19	.	.	PUNCT
brainmatters-1083	18	1	as	as	ADP
brainmatters-1083	18	2	a	a	DET
brainmatters-1083	18	3	result	result	NOUN
brainmatters-1083	18	4	,	,	PUNCT
brainmatters-1083	18	5	brain	brain	NOUN
brainmatters-1083	18	6	volume	volume	NOUN
brainmatters-1083	18	7	decreases	decrease	NOUN
brainmatters-1083	18	8	and	and	CCONJ
brainmatters-1083	18	9	symptoms	symptom	NOUN
brainmatters-1083	18	10	such	such	ADJ
brainmatters-1083	18	11	as	as	ADP
brainmatters-1083	18	12	memory	memory	NOUN
brainmatters-1083	18	13	loss	loss	NOUN
brainmatters-1083	18	14	,	,	PUNCT
brainmatters-1083	18	15	seizures	seizure	NOUN
brainmatters-1083	18	16	,	,	PUNCT
brainmatters-1083	18	17	and	and	CCONJ
brainmatters-1083	18	18	aphasia	aphasia	NOUN
brainmatters-1083	18	19	occur	occur	VERB
brainmatters-1083	18	20	.	.	PUNCT
brainmatters-1083	19	1	while	while	SCONJ
brainmatters-1083	19	2	it	it	PRON
brainmatters-1083	19	3	is	be	AUX
brainmatters-1083	19	4	not	not	PART
brainmatters-1083	19	5	uncommon	uncommon	ADJ
brainmatters-1083	19	6	to	to	PART
brainmatters-1083	19	7	lose	lose	VERB
brainmatters-1083	19	8	neurons	neuron	NOUN
brainmatters-1083	19	9	as	as	SCONJ
brainmatters-1083	19	10	one	one	NUM
brainmatters-1083	19	11	gets	get	VERB
brainmatters-1083	19	12	older	old	ADJ
brainmatters-1083	19	13	,	,	PUNCT
brainmatters-1083	19	14	ba	ba	PROPN
brainmatters-1083	19	15	refers	refer	VERB
brainmatters-1083	19	16	to	to	ADP
brainmatters-1083	19	17	when	when	SCONJ
brainmatters-1083	19	18	an	an	DET
brainmatters-1083	19	19	individual	individual	NOUN
brainmatters-1083	19	20	has	have	AUX
brainmatters-1083	19	21	more	more	ADV
brainmatters-1083	19	22	abnormal	abnormal	ADJ
brainmatters-1083	19	23	brain	brain	NOUN
brainmatters-1083	19	24	changes	change	NOUN
brainmatters-1083	19	25	than	than	ADP
brainmatters-1083	19	26	what	what	PRON
brainmatters-1083	19	27	is	be	AUX
brainmatters-1083	19	28	expected	expect	VERB
brainmatters-1083	19	29	for	for	ADP
brainmatters-1083	19	30	their	their	PRON
brainmatters-1083	19	31	age	age	NOUN
brainmatters-1083	19	32	.	.	PUNCT
brainmatters-1083	20	1	in	in	ADP
brainmatters-1083	20	2	its	its	PRON
brainmatters-1083	20	3	most	most	ADV
brainmatters-1083	20	4	severe	severe	ADJ
brainmatters-1083	20	5	forms	form	NOUN
brainmatters-1083	20	6	,	,	PUNCT
brainmatters-1083	20	7	ba	ba	PROPN
brainmatters-1083	20	8	can	can	AUX
brainmatters-1083	20	9	become	become	VERB
brainmatters-1083	20	10	fatal	fatal	ADJ
brainmatters-1083	20	11	(	(	PUNCT
brainmatters-1083	20	12	harris	harris	PROPN
brainmatters-1083	20	13	tc	tc	PROPN
brainmatters-1083	20	14	,	,	PUNCT
brainmatters-1083	20	15	de	de	X
brainmatters-1083	20	16	rooij	rooij	NOUN
brainmatters-1083	20	17	r	r	PROPN
brainmatters-1083	20	18	,	,	PUNCT
brainmatters-1083	20	19	kuhl	kuhl	PROPN
brainmatters-1083	20	20	e.	e.	PROPN
brainmatters-1083	20	21	,	,	PUNCT
brainmatters-1083	20	22	2019	2019	NUM
brainmatters-1083	20	23	)	)	PUNCT
brainmatters-1083	20	24	.	.	PUNCT
brainmatters-1083	21	1	there	there	PRON
brainmatters-1083	21	2	are	be	VERB
brainmatters-1083	21	3	two	two	NUM
brainmatters-1083	21	4	types	type	NOUN
brainmatters-1083	21	5	of	of	ADP
brainmatters-1083	21	6	ba	ba	PROPN
brainmatters-1083	21	7	,	,	PUNCT
brainmatters-1083	21	8	focal	focal	ADJ
brainmatters-1083	21	9	and	and	CCONJ
brainmatters-1083	21	10	generalized	generalize	VERB
brainmatters-1083	21	11	.	.	PUNCT
brainmatters-1083	22	1	focal	focal	ADJ
brainmatters-1083	22	2	refers	refer	NOUN
brainmatters-1083	22	3	to	to	ADP
brainmatters-1083	22	4	atrophy	atrophy	NOUN
brainmatters-1083	22	5	in	in	ADP
brainmatters-1083	22	6	a	a	DET
brainmatters-1083	22	7	specific	specific	ADJ
brainmatters-1083	22	8	part	part	NOUN
brainmatters-1083	22	9	of	of	ADP
brainmatters-1083	22	10	the	the	DET
brainmatters-1083	22	11	brain	brain	NOUN
brainmatters-1083	22	12	,	,	PUNCT
brainmatters-1083	22	13	and	and	CCONJ
brainmatters-1083	22	14	generalized	generalized	ADJ
brainmatters-1083	22	15	refers	refer	NOUN
brainmatters-1083	22	16	to	to	ADP
brainmatters-1083	22	17	atrophy	atrophy	NOUN
brainmatters-1083	22	18	spread	spread	VERB
brainmatters-1083	22	19	throughout	throughout	ADP
brainmatters-1083	22	20	the	the	DET
brainmatters-1083	22	21	brain	brain	NOUN
brainmatters-1083	22	22	.	.	PUNCT
brainmatters-1083	23	1	another	another	DET
brainmatters-1083	23	2	chronic	chronic	ADJ
brainmatters-1083	23	3	neurological	neurological	ADJ
brainmatters-1083	23	4	disorder	disorder	NOUN
brainmatters-1083	23	5	is	be	AUX
brainmatters-1083	23	6	multiple	multiple	ADJ
brainmatters-1083	23	7	sclerosis	sclerosis	NOUN
brainmatters-1083	23	8	(	(	PUNCT
brainmatters-1083	23	9	ms	ms	PROPN
brainmatters-1083	23	10	)	)	PUNCT
brainmatters-1083	23	11	which	which	PRON
brainmatters-1083	23	12	is	be	AUX
brainmatters-1083	23	13	caused	cause	VERB
brainmatters-1083	23	14	by	by	ADP
brainmatters-1083	23	15	the	the	DET
brainmatters-1083	23	16	autoimmune	autoimmune	ADJ
brainmatters-1083	23	17	system	system	NOUN
brainmatters-1083	23	18	,	,	PUNCT
brainmatters-1083	23	19	inducing	induce	VERB
brainmatters-1083	23	20	the	the	DET
brainmatters-1083	23	21	body	body	NOUN
brainmatters-1083	23	22	to	to	PART
brainmatters-1083	23	23	attack	attack	VERB
brainmatters-1083	23	24	the	the	DET
brainmatters-1083	23	25	central	central	ADJ
brainmatters-1083	23	26	nervous	nervous	ADJ
brainmatters-1083	23	27	system	system	NOUN
brainmatters-1083	23	28	(	(	PUNCT
brainmatters-1083	23	29	cns	cns	NOUN
brainmatters-1083	23	30	)	)	PUNCT
brainmatters-1083	23	31	.	.	PUNCT
brainmatters-1083	24	1	common	common	ADJ
brainmatters-1083	24	2	symptoms	symptom	NOUN
brainmatters-1083	24	3	include	include	VERB
brainmatters-1083	24	4	muscle	muscle	NOUN
brainmatters-1083	24	5	weakness	weakness	NOUN
brainmatters-1083	24	6	,	,	PUNCT
brainmatters-1083	24	7	coordination	coordination	NOUN
brainmatters-1083	24	8	issues	issue	NOUN
brainmatters-1083	24	9	,	,	PUNCT
brainmatters-1083	24	10	cognitive	cognitive	ADJ
brainmatters-1083	24	11	difficulties	difficulty	NOUN
brainmatters-1083	24	12	such	such	ADJ
brainmatters-1083	24	13	as	as	ADP
brainmatters-1083	24	14	memory	memory	NOUN
brainmatters-1083	24	15	problems	problem	NOUN
brainmatters-1083	24	16	,	,	PUNCT
brainmatters-1083	24	17	and	and	CCONJ
brainmatters-1083	24	18	slowed	slow	VERB
brainmatters-1083	24	19	processing	processing	NOUN
brainmatters-1083	24	20	speed	speed	NOUN
brainmatters-1083	24	21	.	.	PUNCT
brainmatters-1083	25	1	the	the	DET
brainmatters-1083	25	2	exact	exact	ADJ
brainmatters-1083	25	3	causes	cause	NOUN
brainmatters-1083	25	4	of	of	ADP
brainmatters-1083	25	5	ms	ms	NOUN
brainmatters-1083	25	6	remain	remain	VERB
brainmatters-1083	25	7	unclear	unclear	ADJ
brainmatters-1083	25	8	,	,	PUNCT
brainmatters-1083	25	9	but	but	CCONJ
brainmatters-1083	25	10	several	several	ADJ
brainmatters-1083	25	11	factors	factor	NOUN
brainmatters-1083	25	12	contribute	contribute	VERB
brainmatters-1083	25	13	,	,	PUNCT
brainmatters-1083	25	14	particularly	particularly	ADV
brainmatters-1083	25	15	genetic	genetic	ADJ
brainmatters-1083	25	16	predisposition	predisposition	NOUN
brainmatters-1083	25	17	.	.	PUNCT
brainmatters-1083	26	1	in	in	ADP
brainmatters-1083	26	2	an	an	DET
brainmatters-1083	26	3	individual	individual	NOUN
brainmatters-1083	26	4	with	with	ADP
brainmatters-1083	26	5	ms	ms	PROPN
brainmatters-1083	26	6	,	,	PUNCT
brainmatters-1083	26	7	the	the	DET
brainmatters-1083	26	8	autoimmune	autoimmune	ADJ
brainmatters-1083	26	9	system	system	NOUN
brainmatters-1083	26	10	attacks	attack	VERB
brainmatters-1083	26	11	the	the	DET
brainmatters-1083	26	12	myelin	myelin	NOUN
brainmatters-1083	26	13	sheath	sheath	NOUN
brainmatters-1083	26	14	surrounding	surround	VERB
brainmatters-1083	26	15	the	the	DET
brainmatters-1083	26	16	body	body	NOUN
brainmatters-1083	26	17	’s	’s	PART
brainmatters-1083	26	18	neurons	neuron	NOUN
brainmatters-1083	26	19	,	,	PUNCT
brainmatters-1083	26	20	which	which	PRON
brainmatters-1083	26	21	disrupts	disrupt	VERB
brainmatters-1083	26	22	communication	communication	NOUN
brainmatters-1083	26	23	between	between	ADP
brainmatters-1083	26	24	neurons	neuron	NOUN
brainmatters-1083	26	25	(	(	PUNCT
brainmatters-1083	26	26	national	national	PROPN
brainmatters-1083	26	27	institute	institute	NOUN
brainmatters-1083	26	28	of	of	ADP
brainmatters-1083	26	29	neurological	neurological	ADJ
brainmatters-1083	26	30	disorders	disorder	NOUN
brainmatters-1083	26	31	and	and	CCONJ
brainmatters-1083	26	32	stroke	stroke	NOUN
brainmatters-1083	26	33	,	,	PUNCT
brainmatters-1083	26	34	2024	2024	NUM
brainmatters-1083	26	35	)	)	PUNCT
brainmatters-1083	26	36	.	.	PUNCT
brainmatters-1083	27	1	the	the	DET
brainmatters-1083	27	2	loss	loss	NOUN
brainmatters-1083	27	3	of	of	ADP
brainmatters-1083	27	4	neuronal	neuronal	ADJ
brainmatters-1083	27	5	connections	connection	NOUN
brainmatters-1083	27	6	caused	cause	VERB
brainmatters-1083	27	7	by	by	ADP
brainmatters-1083	27	8	the	the	DET
brainmatters-1083	27	9	presence	presence	NOUN
brainmatters-1083	27	10	of	of	ADP
brainmatters-1083	27	11	ms	ms	PROPN
brainmatters-1083	27	12	,	,	PUNCT
brainmatters-1083	27	13	is	be	AUX
brainmatters-1083	27	14	also	also	ADV
brainmatters-1083	27	15	an	an	DET
brainmatters-1083	27	16	aforementioned	aforementioned	ADJ
brainmatters-1083	27	17	key	key	ADJ
brainmatters-1083	27	18	symptom	symptom	NOUN
brainmatters-1083	27	19	of	of	ADP
brainmatters-1083	27	20	ba	ba	PROPN
brainmatters-1083	27	21	.	.	PUNCT
brainmatters-1083	28	1	thus	thus	ADV
brainmatters-1083	28	2	,	,	PUNCT
brainmatters-1083	28	3	ms	ms	PROPN
brainmatters-1083	28	4	can	can	AUX
brainmatters-1083	28	5	significantly	significantly	ADV
brainmatters-1083	28	6	worsen	worsen	VERB
brainmatters-1083	28	7	the	the	DET
brainmatters-1083	28	8	damage	damage	NOUN
brainmatters-1083	28	9	done	do	VERB
brainmatters-1083	28	10	by	by	ADP
brainmatters-1083	28	11	atrophy	atrophy	NOUN
brainmatters-1083	28	12	.	.	PUNCT
brainmatters-1083	29	1	in	in	ADP
brainmatters-1083	29	2	addition	addition	NOUN
brainmatters-1083	29	3	,	,	PUNCT
brainmatters-1083	29	4	ms	ms	PROPN
brainmatters-1083	29	5	can	can	AUX
brainmatters-1083	29	6	also	also	ADV
brainmatters-1083	29	7	be	be	AUX
brainmatters-1083	29	8	the	the	DET
brainmatters-1083	29	9	primary	primary	ADJ
brainmatters-1083	29	10	cause	cause	NOUN
brainmatters-1083	29	11	of	of	ADP
brainmatters-1083	29	12	ba	ba	PROPN
brainmatters-1083	29	13	,	,	PUNCT
brainmatters-1083	29	14	when	when	SCONJ
brainmatters-1083	29	15	6	6	NUM
brainmatters-1083	29	16	description	description	NOUN
brainmatters-1083	29	17	of	of	ADP
brainmatters-1083	29	18	hla	hla	PROPN
brainmatters-1083	29	19	class	class	PROPN
brainmatters-1083	29	20	ii	ii	PROPN
brainmatters-1083	29	21	alleles	allele	VERB
brainmatters-1083	29	22	structure	structure	NOUN
brainmatters-1083	29	23	and	and	CCONJ
brainmatters-1083	29	24	function	function	NOUN
brainmatters-1083	29	25	as	as	SCONJ
brainmatters-1083	29	26	seen	see	VERB
brainmatters-1083	29	27	in	in	ADP
brainmatters-1083	29	28	figure	figure	NOUN
brainmatters-1083	29	29	1	1	NUM
brainmatters-1083	29	30	,	,	PUNCT
brainmatters-1083	29	31	the	the	DET
brainmatters-1083	29	32	primary	primary	ADJ
brainmatters-1083	29	33	structural	structural	ADJ
brainmatters-1083	29	34	difference	difference	NOUN
brainmatters-1083	29	35	between	between	ADP
brainmatters-1083	29	36	two	two	NUM
brainmatters-1083	29	37	types	type	NOUN
brainmatters-1083	29	38	of	of	ADP
brainmatters-1083	29	39	human	human	ADJ
brainmatters-1083	29	40	leukocyte	leukocyte	NOUN
brainmatters-1083	29	41	antigens	antigen	NOUN
brainmatters-1083	29	42	is	be	AUX
brainmatters-1083	29	43	that	that	PRON
brainmatters-1083	29	44	class	class	NOUN
brainmatters-1083	29	45	1	1	NUM
brainmatters-1083	29	46	hla	hla	NOUN
brainmatters-1083	29	47	molecules	molecule	NOUN
brainmatters-1083	29	48	have	have	VERB
brainmatters-1083	29	49	1	1	NUM
brainmatters-1083	29	50	polypeptide	polypeptide	ADJ
brainmatters-1083	29	51	chain	chain	NOUN
brainmatters-1083	29	52	,	,	PUNCT
brainmatters-1083	29	53	combined	combine	VERB
brainmatters-1083	29	54	with	with	ADP
brainmatters-1083	29	55	a	a	DET
brainmatters-1083	29	56	beta-2	beta-2	PROPN
brainmatters-1083	29	57	microglobulin	microglobulin	PROPN
brainmatters-1083	29	58	subunit	subunit	NOUN
brainmatters-1083	29	59	while	while	SCONJ
brainmatters-1083	29	60	class	class	NOUN
brainmatters-1083	29	61	ii	ii	PROPN
brainmatters-1083	29	62	molecules	molecule	NOUN
brainmatters-1083	29	63	contain	contain	VERB
brainmatters-1083	29	64	2	2	NUM
brainmatters-1083	29	65	polypeptide	polypeptide	ADJ
brainmatters-1083	29	66	chains	chain	NOUN
brainmatters-1083	29	67	.	.	PUNCT
brainmatters-1083	30	1	this	this	DET
brainmatters-1083	30	2	results	result	VERB
brainmatters-1083	30	3	in	in	ADP
brainmatters-1083	30	4	the	the	DET
brainmatters-1083	30	5	distinct	distinct	ADJ
brainmatters-1083	30	6	roles	role	NOUN
brainmatters-1083	30	7	that	that	PRON
brainmatters-1083	30	8	the	the	DET
brainmatters-1083	30	9	molecules	molecule	NOUN
brainmatters-1083	30	10	play	play	VERB
brainmatters-1083	30	11	in	in	ADP
brainmatters-1083	30	12	the	the	DET
brainmatters-1083	30	13	human	human	ADJ
brainmatters-1083	30	14	body	body	NOUN
brainmatters-1083	30	15	.	.	PUNCT
brainmatters-1083	31	1	for	for	ADP
brainmatters-1083	31	2	populations	population	NOUN
brainmatters-1083	31	3	that	that	PRON
brainmatters-1083	31	4	express	express	VERB
brainmatters-1083	31	5	a	a	DET
brainmatters-1083	31	6	high	high	ADJ
brainmatters-1083	31	7	frequency	frequency	NOUN
brainmatters-1083	31	8	of	of	ADP
brainmatters-1083	31	9	drb1	drb1	PROPN
brainmatters-1083	31	10	*	*	NUM
brainmatters-1083	31	11	1302	1302	NUM
brainmatters-1083	31	12	,	,	PUNCT
brainmatters-1083	31	13	neurodegeneration	neurodegeneration	NOUN
brainmatters-1083	31	14	can	can	AUX
brainmatters-1083	31	15	be	be	AUX
brainmatters-1083	31	16	slowed	slow	VERB
brainmatters-1083	31	17	by	by	ADP
brainmatters-1083	31	18	around	around	ADP
brainmatters-1083	31	19	45.2	45.2	NUM
brainmatters-1083	31	20	%	%	NOUN
brainmatters-1083	31	21	.	.	PUNCT
brainmatters-1083	32	1	scientists	scientist	NOUN
brainmatters-1083	32	2	hypothesize	hypothesize	VERB
brainmatters-1083	32	3	that	that	SCONJ
brainmatters-1083	32	4	its	its	PRON
brainmatters-1083	32	5	protective	protective	ADJ
brainmatters-1083	32	6	effect	effect	NOUN
brainmatters-1083	32	7	could	could	AUX
brainmatters-1083	32	8	be	be	AUX
brainmatters-1083	32	9	due	due	ADJ
brainmatters-1083	32	10	to	to	ADP
brainmatters-1083	32	11	the	the	DET
brainmatters-1083	32	12	removal	removal	NOUN
brainmatters-1083	32	13	of	of	ADP
brainmatters-1083	32	14	antigens	antigen	NOUN
brainmatters-1083	32	15	that	that	PRON
brainmatters-1083	32	16	persist	persist	VERB
brainmatters-1083	32	17	in	in	ADP
brainmatters-1083	32	18	causing	cause	VERB
brainmatters-1083	32	19	gradual	gradual	ADJ
brainmatters-1083	32	20	brain	brain	NOUN
brainmatters-1083	32	21	atrophy	atrophy	NOUN
brainmatters-1083	32	22	.	.	PUNCT
brainmatters-1083	33	1	these	these	DET
brainmatters-1083	33	2	beneficial	beneficial	ADJ
brainmatters-1083	33	3	effects	effect	NOUN
brainmatters-1083	33	4	have	have	AUX
brainmatters-1083	33	5	also	also	ADV
brainmatters-1083	33	6	been	be	AUX
brainmatters-1083	33	7	attributed	attribute	VERB
brainmatters-1083	33	8	to	to	ADP
brainmatters-1083	33	9	drb1	drb1	PROPN
brainmatters-1083	33	10	*	*	PROPN
brainmatters-1083	33	11	13:02	13:02	NUM
brainmatters-1083	33	12	’s	’s	PART
brainmatters-1083	33	13	binding	bind	VERB
brainmatters-1083	33	14	to	to	ADP
brainmatters-1083	33	15	cathepsin	cathepsin	NOUN
brainmatters-1083	33	16	s	s	PROPN
brainmatters-1083	33	17	,	,	PUNCT
brainmatters-1083	33	18	a	a	DET
brainmatters-1083	33	19	known	know	VERB
brainmatters-1083	33	20	harmful	harmful	ADJ
brainmatters-1083	33	21	substance	substance	NOUN
brainmatters-1083	33	22	in	in	ADP
brainmatters-1083	33	23	brain	brain	NOUN
brainmatters-1083	33	24	aging	aging	NOUN
brainmatters-1083	33	25	(	(	PUNCT
brainmatters-1083	33	26	james	james	PROPN
brainmatters-1083	33	27	,	,	PUNCT
brainmatters-1083	33	28	l.	l.	PROPN
brainmatters-1083	33	29	m.	m.	PROPN
brainmatters-1083	33	30	,	,	PUNCT
brainmatters-1083	33	31	&	&	CCONJ
brainmatters-1083	33	32	georgopoulos	georgopoulo	NOUN
brainmatters-1083	33	33	,	,	PUNCT
brainmatters-1083	33	34	a.	a.	NOUN
brainmatters-1083	33	35	p.	p.	NOUN
brainmatters-1083	33	36	,	,	PUNCT
brainmatters-1083	33	37	2019	2019	NUM
brainmatters-1083	33	38	)	)	PUNCT
brainmatters-1083	33	39	.	.	PUNCT
brainmatters-1083	34	1	this	this	PRON
brainmatters-1083	34	2	is	be	AUX
brainmatters-1083	34	3	best	well	ADV
brainmatters-1083	34	4	demonstrated	demonstrate	VERB
brainmatters-1083	34	5	in	in	ADP
brainmatters-1083	34	6	the	the	DET
brainmatters-1083	34	7	research	research	NOUN
brainmatters-1083	34	8	done	do	VERB
brainmatters-1083	34	9	on	on	ADP
brainmatters-1083	34	10	drb1	drb1	PROPN
brainmatters-1083	34	11	*	*	SYM
brainmatters-1083	34	12	1302	1302	NUM
brainmatters-1083	34	13	’s	’s	PART
brainmatters-1083	34	14	effect	effect	NOUN
brainmatters-1083	34	15	on	on	ADP
brainmatters-1083	34	16	dementia	dementia	NOUN
brainmatters-1083	34	17	and	and	CCONJ
brainmatters-1083	34	18	gulf	gulf	PROPN
brainmatters-1083	34	19	war	war	NOUN
brainmatters-1083	34	20	illness	illness	NOUN
brainmatters-1083	34	21	,	,	PUNCT
brainmatters-1083	34	22	which	which	PRON
brainmatters-1083	34	23	are	be	AUX
brainmatters-1083	34	24	both	both	PRON
brainmatters-1083	34	25	caused	cause	VERB
brainmatters-1083	34	26	by	by	ADP
brainmatters-1083	34	27	some	some	DET
brainmatters-1083	34	28	levels	level	NOUN
brainmatters-1083	34	29	of	of	ADP
brainmatters-1083	34	30	neurodegeneration	neurodegeneration	NOUN
brainmatters-1083	34	31	.	.	PUNCT
brainmatters-1083	35	1	thus	thus	ADV
brainmatters-1083	35	2	,	,	PUNCT
brainmatters-1083	35	3	it	it	PRON
brainmatters-1083	35	4	is	be	AUX
brainmatters-1083	35	5	reasonable	reasonable	ADJ
brainmatters-1083	35	6	to	to	PART
brainmatters-1083	35	7	assume	assume	VERB
brainmatters-1083	35	8	that	that	SCONJ
brainmatters-1083	35	9	drb1	drb1	PROPN
brainmatters-1083	35	10	*	*	SYM
brainmatters-1083	35	11	1302	1302	NUM
brainmatters-1083	35	12	demonstrates	demonstrate	VERB
brainmatters-1083	35	13	preventative	preventative	ADJ
brainmatters-1083	35	14	effects	effect	NOUN
brainmatters-1083	35	15	against	against	ADP
brainmatters-1083	35	16	general	general	ADJ
brainmatters-1083	35	17	atrophy	atrophy	NOUN
brainmatters-1083	35	18	of	of	ADP
brainmatters-1083	35	19	the	the	DET
brainmatters-1083	35	20	brain	brain	NOUN
brainmatters-1083	35	21	.	.	PUNCT
brainmatters-1083	36	1	class	class	NOUN
brainmatters-1083	36	2	i	i	PRON
brainmatters-1083	36	3	molecules	molecule	NOUN
brainmatters-1083	36	4	are	be	AUX
brainmatters-1083	36	5	responsible	responsible	ADJ
brainmatters-1083	36	6	for	for	ADP
brainmatters-1083	36	7	facilitating	facilitate	VERB
brainmatters-1083	36	8	cell	cell	NOUN
brainmatters-1083	36	9	destruction	destruction	NOUN
brainmatters-1083	36	10	,	,	PUNCT
brainmatters-1083	36	11	whereas	whereas	SCONJ
brainmatters-1083	36	12	class	class	NOUN
brainmatters-1083	36	13	ii	ii	PROPN
brainmatters-1083	36	14	molecules	molecule	NOUN
brainmatters-1083	36	15	are	be	AUX
brainmatters-1083	36	16	responsible	responsible	ADJ
brainmatters-1083	36	17	for	for	ADP
brainmatters-1083	36	18	recognizing	recognize	VERB
brainmatters-1083	36	19	invaders	invader	NOUN
brainmatters-1083	36	20	and	and	CCONJ
brainmatters-1083	36	21	producing	produce	VERB
brainmatters-1083	36	22	the	the	DET
brainmatters-1083	36	23	appropriate	appropriate	ADJ
brainmatters-1083	36	24	antibodies	antibody	NOUN
brainmatters-1083	36	25	(	(	PUNCT
brainmatters-1083	36	26	james	james	PROPN
brainmatters-1083	36	27	,	,	PUNCT
brainmatters-1083	36	28	l.	l.	PROPN
brainmatters-1083	36	29	m.	m.	PROPN
brainmatters-1083	36	30	,	,	PUNCT
brainmatters-1083	36	31	&	&	CCONJ
brainmatters-1083	36	32	georgopoulos	georgopoulo	NOUN
brainmatters-1083	36	33	,	,	PUNCT
brainmatters-1083	36	34	a.	a.	NOUN
brainmatters-1083	36	35	p.	p.	NOUN
brainmatters-1083	36	36	,	,	PUNCT
brainmatters-1083	36	37	2019	2019	NUM
brainmatters-1083	36	38	)	)	PUNCT
brainmatters-1083	36	39	.	.	PUNCT
brainmatters-1083	37	1	however	however	ADV
brainmatters-1083	37	2	,	,	PUNCT
brainmatters-1083	37	3	since	since	SCONJ
brainmatters-1083	37	4	class	class	PROPN
brainmatters-1083	37	5	ii	ii	PROPN
brainmatters-1083	37	6	hla	hla	PROPN
brainmatters-1083	37	7	binds	bind	VERB
brainmatters-1083	37	8	to	to	ADP
brainmatters-1083	37	9	antigen	antigen	ADV
brainmatters-1083	37	10	-	-	PUNCT
brainmatters-1083	37	11	presenting	present	VERB
brainmatters-1083	37	12	cells	cell	NOUN
brainmatters-1083	37	13	(	(	PUNCT
brainmatters-1083	37	14	apc	apc	PROPN
brainmatters-1083	37	15	)	)	PUNCT
brainmatters-1083	37	16	and	and	CCONJ
brainmatters-1083	37	17	is	be	AUX
brainmatters-1083	37	18	ultimately	ultimately	ADV
brainmatters-1083	37	19	responsible	responsible	ADJ
brainmatters-1083	37	20	for	for	ADP
brainmatters-1083	37	21	determining	determine	VERB
brainmatters-1083	37	22	what	what	PRON
brainmatters-1083	37	23	the	the	DET
brainmatters-1083	37	24	body	body	NOUN
brainmatters-1083	37	25	considers	consider	VERB
brainmatters-1083	37	26	a	a	DET
brainmatters-1083	37	27	harmful	harmful	ADJ
brainmatters-1083	37	28	microorganism	microorganism	NOUN
brainmatters-1083	37	29	,	,	PUNCT
brainmatters-1083	37	30	a	a	DET
brainmatters-1083	37	31	miscoding	miscoding	NOUN
brainmatters-1083	37	32	in	in	ADP
brainmatters-1083	37	33	certain	certain	ADJ
brainmatters-1083	37	34	alleles	allele	NOUN
brainmatters-1083	37	35	can	can	AUX
brainmatters-1083	37	36	cause	cause	VERB
brainmatters-1083	37	37	the	the	DET
brainmatters-1083	37	38	body	body	NOUN
brainmatters-1083	37	39	to	to	PART
brainmatters-1083	37	40	attack	attack	VERB
brainmatters-1083	37	41	itself	itself	PRON
brainmatters-1083	37	42	,	,	PUNCT
brainmatters-1083	37	43	known	know	VERB
brainmatters-1083	37	44	as	as	ADP
brainmatters-1083	37	45	an	an	DET
brainmatters-1083	37	46	autoimmune	autoimmune	ADJ
brainmatters-1083	37	47	disorder	disorder	NOUN
brainmatters-1083	37	48	.	.	PUNCT
brainmatters-1083	38	1	as	as	SCONJ
brainmatters-1083	38	2	previously	previously	ADV
brainmatters-1083	38	3	stated	state	VERB
brainmatters-1083	38	4	,	,	PUNCT
brainmatters-1083	38	5	ms	ms	PROPN
brainmatters-1083	38	6	is	be	AUX
brainmatters-1083	38	7	classified	classify	VERB
brainmatters-1083	38	8	as	as	ADP
brainmatters-1083	38	9	an	an	DET
brainmatters-1083	38	10	autoimmune	autoimmune	ADJ
brainmatters-1083	38	11	disorder	disorder	NOUN
brainmatters-1083	38	12	,	,	PUNCT
brainmatters-1083	38	13	meaning	mean	VERB
brainmatters-1083	38	14	that	that	SCONJ
brainmatters-1083	38	15	the	the	DET
brainmatters-1083	38	16	introduction	introduction	NOUN
brainmatters-1083	38	17	of	of	ADP
brainmatters-1083	38	18	ms	ms	NOUN
brainmatters-1083	38	19	in	in	ADP
brainmatters-1083	38	20	the	the	DET
brainmatters-1083	38	21	body	body	NOUN
brainmatters-1083	38	22	is	be	AUX
brainmatters-1083	38	23	almost	almost	ADV
brainmatters-1083	38	24	entirely	entirely	ADV
brainmatters-1083	38	25	due	due	ADJ
brainmatters-1083	38	26	to	to	ADP
brainmatters-1083	38	27	class	class	PROPN
brainmatters-1083	38	28	ii	ii	PROPN
brainmatters-1083	38	29	hla	hla	PROPN
brainmatters-1083	38	30	molecules	molecule	NOUN
brainmatters-1083	38	31	.	.	PUNCT
brainmatters-1083	39	1	this	this	PRON
brainmatters-1083	39	2	is	be	AUX
brainmatters-1083	39	3	why	why	SCONJ
brainmatters-1083	39	4	class	class	PROPN
brainmatters-1083	39	5	ii	ii	PROPN
brainmatters-1083	39	6	hla	hla	PROPN
brainmatters-1083	39	7	molecules	molecule	NOUN
brainmatters-1083	39	8	are	be	AUX
brainmatters-1083	39	9	the	the	DET
brainmatters-1083	39	10	primary	primary	ADJ
brainmatters-1083	39	11	focus	focus	NOUN
brainmatters-1083	39	12	concerning	concern	VERB
brainmatters-1083	39	13	ba	ba	PROPN
brainmatters-1083	39	14	and	and	CCONJ
brainmatters-1083	39	15	ms	ms	PROPN
brainmatters-1083	39	16	.	.	PROPN
brainmatters-1083	40	1	the	the	DET
brainmatters-1083	40	2	role	role	NOUN
brainmatters-1083	40	3	of	of	ADP
brainmatters-1083	40	4	human	human	ADJ
brainmatters-1083	40	5	leukocyte	leukocyte	NOUN
brainmatters-1083	40	6	antigens	antigen	NOUN
brainmatters-1083	40	7	in	in	ADP
brainmatters-1083	40	8	multiple	multiple	ADJ
brainmatters-1083	40	9	sclerosis	sclerosis	NOUN
brainmatters-1083	40	10	and	and	CCONJ
brainmatters-1083	40	11	brain	brain	NOUN
brainmatters-1083	40	12	atrophy	atrophy	NOUN
brainmatters-1083	40	13	the	the	DET
brainmatters-1083	40	14	protective	protective	ADJ
brainmatters-1083	40	15	effects	effect	NOUN
brainmatters-1083	40	16	of	of	ADP
brainmatters-1083	40	17	drb1	drb1	NOUN
brainmatters-1083	40	18	*	*	NOUN
brainmatters-1083	40	19	1302	1302	NUM
brainmatters-1083	40	20	on	on	ADP
brainmatters-1083	40	21	demyelination	demyelination	NOUN
brainmatters-1083	40	22	and	and	CCONJ
brainmatters-1083	40	23	atrophy	atrophy	NOUN
brainmatters-1083	40	24	studies	study	NOUN
brainmatters-1083	40	25	have	have	AUX
brainmatters-1083	40	26	discovered	discover	VERB
brainmatters-1083	40	27	that	that	SCONJ
brainmatters-1083	40	28	the	the	DET
brainmatters-1083	40	29	frequency	frequency	NOUN
brainmatters-1083	40	30	of	of	ADP
brainmatters-1083	40	31	class	class	PROPN
brainmatters-1083	40	32	ii	ii	PROPN
brainmatters-1083	40	33	hladrb1	hladrb1	PROPN
brainmatters-1083	40	34	*	*	SYM
brainmatters-1083	40	35	1302	1302	NUM
brainmatters-1083	40	36	has	have	VERB
brainmatters-1083	40	37	an	an	DET
brainmatters-1083	40	38	inverse	inverse	NOUN
brainmatters-1083	40	39	association	association	NOUN
brainmatters-1083	40	40	with	with	ADP
brainmatters-1083	40	41	dementia	dementia	PROPN
brainmatters-1083	40	42	,	,	PUNCT
brainmatters-1083	40	43	which	which	PRON
brainmatters-1083	40	44	is	be	AUX
brainmatters-1083	40	45	caused	cause	VERB
brainmatters-1083	40	46	by	by	ADP
brainmatters-1083	40	47	the	the	DET
brainmatters-1083	40	48	loss	loss	NOUN
brainmatters-1083	40	49	of	of	ADP
brainmatters-1083	40	50	synaptic	synaptic	ADJ
brainmatters-1083	40	51	connections	connection	NOUN
brainmatters-1083	40	52	,	,	PUNCT
brainmatters-1083	40	53	in	in	ADP
brainmatters-1083	40	54	14	14	NUM
brainmatters-1083	40	55	western	western	ADJ
brainmatters-1083	40	56	european	european	ADJ
brainmatters-1083	40	57	countries	country	NOUN
brainmatters-1083	40	58	(	(	PUNCT
brainmatters-1083	40	59	james	james	PROPN
brainmatters-1083	40	60	,	,	PUNCT
brainmatters-1083	40	61	l.	l.	PROPN
brainmatters-1083	40	62	m.	m.	PROPN
brainmatters-1083	40	63	,	,	PUNCT
brainmatters-1083	40	64	&	&	CCONJ
brainmatters-1083	40	65	georgopoulos	georgopoulo	NOUN
brainmatters-1083	40	66	,	,	PUNCT
brainmatters-1083	40	67	a.	a.	NOUN
brainmatters-1083	40	68	p.	p.	NOUN
brainmatters-1083	40	69	,	,	PUNCT
brainmatters-1083	40	70	2019	2019	NUM
brainmatters-1083	40	71	)	)	PUNCT
brainmatters-1083	40	72	.	.	PUNCT
brainmatters-1083	41	1	as	as	SCONJ
brainmatters-1083	41	2	displayed	display	VERB
brainmatters-1083	41	3	in	in	ADP
brainmatters-1083	41	4	figure	figure	NOUN
brainmatters-1083	41	5	2	2	NUM
brainmatters-1083	41	6	,	,	PUNCT
brainmatters-1083	41	7	this	this	PRON
brainmatters-1083	41	8	is	be	AUX
brainmatters-1083	41	9	suspected	suspect	VERB
brainmatters-1083	41	10	to	to	PART
brainmatters-1083	41	11	be	be	AUX
brainmatters-1083	41	12	due	due	ADJ
brainmatters-1083	41	13	to	to	ADP
brainmatters-1083	41	14	the	the	DET
brainmatters-1083	41	15	fact	fact	NOUN
brainmatters-1083	41	16	that	that	SCONJ
brainmatters-1083	41	17	the	the	DET
brainmatters-1083	41	18	hla	hla	PROPN
brainmatters-1083	41	19	drb1	drb1	PROPN
brainmatters-1083	41	20	*	*	SYM
brainmatters-1083	41	21	1302	1302	NUM
brainmatters-1083	41	22	allele	allele	NOUN
brainmatters-1083	41	23	helps	help	VERB
brainmatters-1083	41	24	encode	encode	VERB
brainmatters-1083	41	25	for	for	ADP
brainmatters-1083	41	26	antibodies	antibody	NOUN
brainmatters-1083	41	27	that	that	PRON
brainmatters-1083	41	28	specifically	specifically	ADV
brainmatters-1083	41	29	protect	protect	VERB
brainmatters-1083	41	30	against	against	ADP
brainmatters-1083	41	31	pathogens	pathogen	NOUN
brainmatters-1083	41	32	that	that	PRON
brainmatters-1083	41	33	cause	cause	VERB
brainmatters-1083	41	34	neurodegeneration	neurodegeneration	NOUN
brainmatters-1083	41	35	.	.	PUNCT
brainmatters-1083	42	1	dementia	dementia	NOUN
brainmatters-1083	42	2	is	be	AUX
brainmatters-1083	42	3	linked	link	VERB
brainmatters-1083	42	4	to	to	PART
brainmatters-1083	42	5	ba	ba	VERB
brainmatters-1083	42	6	through	through	ADP
brainmatters-1083	42	7	the	the	DET
brainmatters-1083	42	8	most	most	ADV
brainmatters-1083	42	9	prominent	prominent	ADJ
brainmatters-1083	42	10	symptoms	symptom	NOUN
brainmatters-1083	42	11	of	of	ADP
brainmatters-1083	42	12	neurodegeneration	neurodegeneration	NOUN
brainmatters-1083	42	13	,	,	PUNCT
brainmatters-1083	42	14	loss	loss	NOUN
brainmatters-1083	42	15	of	of	ADP
brainmatters-1083	42	16	memory	memory	NOUN
brainmatters-1083	42	17	.	.	PUNCT
brainmatters-1083	43	1	since	since	SCONJ
brainmatters-1083	43	2	the	the	DET
brainmatters-1083	43	3	frequency	frequency	NOUN
brainmatters-1083	43	4	of	of	ADP
brainmatters-1083	43	5	the	the	DET
brainmatters-1083	43	6	drb1	drb1	PROPN
brainmatters-1083	43	7	*	*	SYM
brainmatters-1083	43	8	1302	1302	NUM
brainmatters-1083	43	9	allele	allele	NOUN
brainmatters-1083	43	10	has	have	VERB
brainmatters-1083	43	11	an	an	DET
brainmatters-1083	43	12	inverse	inverse	NOUN
brainmatters-1083	43	13	association	association	NOUN
brainmatters-1083	43	14	with	with	ADP
brainmatters-1083	43	15	the	the	DET
brainmatters-1083	43	16	loss	loss	NOUN
brainmatters-1083	43	17	of	of	ADP
brainmatters-1083	43	18	synaptic	synaptic	ADJ
brainmatters-1083	43	19	connections	connection	NOUN
brainmatters-1083	43	20	,	,	PUNCT
brainmatters-1083	43	21	it	it	PRON
brainmatters-1083	43	22	is	be	AUX
brainmatters-1083	43	23	suspected	suspect	VERB
brainmatters-1083	43	24	that	that	SCONJ
brainmatters-1083	43	25	the	the	DET
brainmatters-1083	43	26	allele	allele	NOUN
brainmatters-1083	43	27	protects	protect	VERB
brainmatters-1083	43	28	against	against	ADP
brainmatters-1083	43	29	pathogens	pathogen	NOUN
brainmatters-1083	43	30	that	that	PRON
brainmatters-1083	43	31	cause	cause	VERB
brainmatters-1083	43	32	this	this	DET
brainmatters-1083	43	33	neurological	neurological	ADJ
brainmatters-1083	43	34	degeneration	degeneration	NOUN
brainmatters-1083	43	35	,	,	PUNCT
brainmatters-1083	43	36	which	which	PRON
brainmatters-1083	43	37	in	in	ADP
brainmatters-1083	43	38	turn	turn	NOUN
brainmatters-1083	43	39	causes	cause	VERB
brainmatters-1083	43	40	ba	ba	PROPN
brainmatters-1083	43	41	.	.	PUNCT
brainmatters-1083	44	1	therefore	therefore	ADV
brainmatters-1083	44	2	,	,	PUNCT
brainmatters-1083	44	3	it	it	PRON
brainmatters-1083	44	4	is	be	AUX
brainmatters-1083	44	5	reasonable	reasonable	ADJ
brainmatters-1083	44	6	to	to	PART
brainmatters-1083	44	7	assert	assert	VERB
brainmatters-1083	44	8	that	that	SCONJ
brainmatters-1083	44	9	the	the	DET
brainmatters-1083	44	10	presence	presence	NOUN
brainmatters-1083	44	11	of	of	ADP
brainmatters-1083	44	12	the	the	DET
brainmatters-1083	44	13	drb1	drb1	PROPN
brainmatters-1083	44	14	*	*	SYM
brainmatters-1083	44	15	1302	1302	NUM
brainmatters-1083	44	16	allele	allele	NOUN
brainmatters-1083	44	17	has	have	VERB
brainmatters-1083	44	18	an	an	DET
brainmatters-1083	44	19	inverse	inverse	ADJ
brainmatters-1083	44	20	effect	effect	NOUN
brainmatters-1083	44	21	on	on	ADP
brainmatters-1083	44	22	the	the	DET
brainmatters-1083	44	23	onset	onset	NOUN
brainmatters-1083	44	24	of	of	ADP
brainmatters-1083	44	25	dementia	dementia	NOUN
brainmatters-1083	44	26	,	,	PUNCT
brainmatters-1083	44	27	and	and	CCONJ
brainmatters-1083	44	28	thus	thus	ADV
brainmatters-1083	44	29	the	the	DET
brainmatters-1083	44	30	onset	onset	NOUN
brainmatters-1083	44	31	of	of	ADP
brainmatters-1083	44	32	ba	ba	PROPN
brainmatters-1083	44	33	.	.	PUNCT
brainmatters-1083	45	1	the	the	DET
brainmatters-1083	45	2	harmful	harmful	ADJ
brainmatters-1083	45	3	effects	effect	NOUN
brainmatters-1083	45	4	of	of	ADP
brainmatters-1083	45	5	drb1	drb1	NOUN
brainmatters-1083	45	6	*	*	NOUN
brainmatters-1083	45	7	1501	1501	NUM
brainmatters-1083	45	8	on	on	ADP
brainmatters-1083	45	9	ms	ms	NOUN
brainmatters-1083	45	10	and	and	CCONJ
brainmatters-1083	45	11	brain	brain	NOUN
brainmatters-1083	45	12	atrophy	atrophy	NOUN
brainmatters-1083	45	13	hla	hla	PROPN
brainmatters-1083	45	14	-	-	PUNCT
brainmatters-1083	45	15	drb1	drb1	NOUN
brainmatters-1083	45	16	*	*	NOUN
brainmatters-1083	45	17	1501	1501	NUM
brainmatters-1083	45	18	is	be	AUX
brainmatters-1083	45	19	an	an	DET
brainmatters-1083	45	20	hla	hla	PROPN
brainmatters-1083	45	21	haplotype	haplotype	NOUN
brainmatters-1083	45	22	,	,	PUNCT
brainmatters-1083	45	23	a	a	DET
brainmatters-1083	45	24	group	group	NOUN
brainmatters-1083	45	25	of	of	ADP
brainmatters-1083	45	26	closely	closely	ADV
brainmatters-1083	45	27	linked	link	VERB
brainmatters-1083	45	28	alleles	allele	NOUN
brainmatters-1083	45	29	that	that	PRON
brainmatters-1083	45	30	are	be	AUX
brainmatters-1083	45	31	frequently	frequently	ADV
brainmatters-1083	45	32	inherited	inherit	VERB
brainmatters-1083	45	33	together	together	ADV
brainmatters-1083	45	34	and	and	CCONJ
brainmatters-1083	45	35	has	have	AUX
brainmatters-1083	45	36	been	be	AUX
brainmatters-1083	45	37	linked	link	VERB
brainmatters-1083	45	38	to	to	ADP
brainmatters-1083	45	39	a	a	DET
brainmatters-1083	45	40	significantly	significantly	ADV
brainmatters-1083	45	41	higher	high	ADJ
brainmatters-1083	45	42	risk	risk	NOUN
brainmatters-1083	45	43	of	of	ADP
brainmatters-1083	45	44	ms	ms	NOUN
brainmatters-1083	45	45	,	,	PUNCT
brainmatters-1083	45	46	and	and	CCONJ
brainmatters-1083	45	47	consequently	consequently	ADV
brainmatters-1083	45	48	,	,	PUNCT
brainmatters-1083	45	49	also	also	ADV
brainmatters-1083	45	50	to	to	ADP
brainmatters-1083	45	51	ba	ba	PROPN
brainmatters-1083	45	52	(	(	PUNCT
brainmatters-1083	45	53	scholz	scholz	PROPN
brainmatters-1083	45	54	,	,	PUNCT
brainmatters-1083	45	55	e.	e.	PROPN
brainmatters-1083	45	56	m	m	PROPN
brainmatters-1083	45	57	,	,	PUNCT
brainmatters-1083	45	58	marcilla	marcilla	NOUN
brainmatters-1083	45	59	,	,	PUNCT
brainmatters-1083	45	60	m	m	PROPN
brainmatters-1083	45	61	,	,	PUNCT
brainmatters-1083	45	62	daura	daura	NOUN
brainmatters-1083	45	63	,	,	PUNCT
brainmatters-1083	45	64	x	x	PRON
brainmatters-1083	45	65	,	,	PUNCT
brainmatters-1083	45	66	et	et	PROPN
brainmatters-1083	45	67	al	al	PROPN
brainmatters-1083	45	68	.	.	PROPN
brainmatters-1083	45	69	,	,	PUNCT
brainmatters-1083	45	70	2017	2017	NUM
brainmatters-1083	45	71	)	)	PUNCT
brainmatters-1083	45	72	.	.	PUNCT
brainmatters-1083	46	1	in	in	ADP
brainmatters-1083	46	2	fact	fact	NOUN
brainmatters-1083	46	3	,	,	PUNCT
brainmatters-1083	46	4	drb1	drb1	PROPN
brainmatters-1083	46	5	*	*	NOUN
brainmatters-1083	46	6	1501	1501	NUM
brainmatters-1083	46	7	is	be	AUX
brainmatters-1083	46	8	the	the	DET
brainmatters-1083	46	9	single	single	ADJ
brainmatters-1083	46	10	strongest	strong	ADJ
brainmatters-1083	46	11	genetic	genetic	ADJ
brainmatters-1083	46	12	factor	factor	NOUN
brainmatters-1083	46	13	in	in	ADP
brainmatters-1083	46	14	the	the	DET
brainmatters-1083	46	15	development	development	NOUN
brainmatters-1083	46	16	of	of	ADP
brainmatters-1083	46	17	ms	ms	PROPN
brainmatters-1083	46	18	.	.	PROPN
brainmatters-1083	46	19	while	while	SCONJ
brainmatters-1083	46	20	t	t	PROPN
brainmatters-1083	46	21	-	-	PUNCT
brainmatters-1083	46	22	cells	cell	NOUN
brainmatters-1083	46	23	are	be	AUX
brainmatters-1083	46	24	n’t	not	PART
brainmatters-1083	46	25	typically	typically	ADV
brainmatters-1083	46	26	considered	consider	VERB
brainmatters-1083	46	27	apc	apc	PROPN
brainmatters-1083	46	28	,	,	PUNCT
brainmatters-1083	46	29	they	they	PRON
brainmatters-1083	46	30	do	do	AUX
brainmatters-1083	46	31	express	express	VERB
brainmatters-1083	46	32	major	major	ADJ
brainmatters-1083	46	33	histocompatibility	histocompatibility	NOUN
brainmatters-1083	46	34	complex	complex	NOUN
brainmatters-1083	46	35	(	(	PUNCT
brainmatters-1083	46	36	mhc	mhc	PROPN
brainmatters-1083	46	37	is	be	AUX
brainmatters-1083	46	38	known	know	VERB
brainmatters-1083	46	39	as	as	ADP
brainmatters-1083	46	40	hla	hla	PROPN
brainmatters-1083	46	41	in	in	ADP
brainmatters-1083	46	42	humans	human	NOUN
brainmatters-1083	46	43	)	)	PUNCT
brainmatters-1083	46	44	class	class	NOUN
brainmatters-1083	46	45	ii	ii	NOUN
brainmatters-1083	46	46	antigens	antigen	NOUN
brainmatters-1083	46	47	,	,	PUNCT
brainmatters-1083	46	48	which	which	PRON
brainmatters-1083	46	49	are	be	AUX
brainmatters-1083	46	50	precisely	precisely	ADV
brainmatters-1083	46	51	what	what	PRON
brainmatters-1083	46	52	class	class	NOUN
brainmatters-1083	46	53	ii	ii	PROPN
brainmatters-1083	46	54	hla	hla	PROPN
brainmatters-1083	46	55	control	control	NOUN
brainmatters-1083	46	56	(	(	PUNCT
brainmatters-1083	46	57	pichler	pichler	NOUN
brainmatters-1083	46	58	,	,	PUNCT
brainmatters-1083	46	59	w.	w.	PROPN
brainmatters-1083	46	60	j	j	PROPN
brainmatters-1083	46	61	&	&	CCONJ
brainmatters-1083	46	62	wyss	wyss	PROPN
brainmatters-1083	46	63	-	-	PUNCT
brainmatters-1083	46	64	coray	coray	NOUN
brainmatters-1083	46	65	,	,	PUNCT
brainmatters-1083	46	66	t	t	PROPN
brainmatters-1083	46	67	,	,	PUNCT
brainmatters-1083	46	68	1994	1994	NUM
brainmatters-1083	46	69	)	)	PUNCT
brainmatters-1083	46	70	.	.	PUNCT
brainmatters-1083	47	1	figure	figure	VERB
brainmatters-1083	47	2	1	1	NUM
brainmatters-1083	47	3	:	:	PUNCT
brainmatters-1083	47	4	structure	structure	NOUN
brainmatters-1083	47	5	of	of	ADP
brainmatters-1083	47	6	class	class	NOUN
brainmatters-1083	47	7	i	i	PROPN
brainmatters-1083	47	8	and	and	CCONJ
brainmatters-1083	47	9	class	class	PROPN
brainmatters-1083	47	10	ii	ii	PROPN
brainmatters-1083	47	11	hla	hla	PROPN
brainmatters-1083	47	12	molecules	molecule	NOUN
brainmatters-1083	47	13	(	(	PUNCT
brainmatters-1083	47	14	grubic	grubic	ADJ
brainmatters-1083	47	15	,	,	PUNCT
brainmatters-1083	47	16	2017	2017	NUM
brainmatters-1083	47	17	)	)	PUNCT
brainmatters-1083	47	18	.	.	PUNCT
brainmatters-1083	48	1	7	7	NUM
brainmatters-1083	48	2	figure	figure	NOUN
brainmatters-1083	48	3	2	2	NUM
brainmatters-1083	48	4	:	:	PUNCT
brainmatters-1083	48	5	flowchart	flowchart	NOUN
brainmatters-1083	48	6	demonstrating	demonstrating	NOUN
brainmatters-1083	48	7	link	link	NOUN
brainmatters-1083	48	8	between	between	ADP
brainmatters-1083	48	9	decreased	decrease	VERB
brainmatters-1083	48	10	hla	hla	PROPN
brainmatters-1083	48	11	and	and	CCONJ
brainmatters-1083	48	12	dementia	dementia	PROPN
brainmatters-1083	48	13	(	(	PUNCT
brainmatters-1083	48	14	james	james	PROPN
brainmatters-1083	48	15	,	,	PUNCT
brainmatters-1083	48	16	l.	l.	PROPN
brainmatters-1083	48	17	m.	m.	PROPN
brainmatters-1083	48	18	,	,	PUNCT
brainmatters-1083	48	19	&	&	CCONJ
brainmatters-1083	48	20	georgopoulos	georgopoulo	NOUN
brainmatters-1083	48	21	,	,	PUNCT
brainmatters-1083	48	22	a.	a.	NOUN
brainmatters-1083	48	23	p.	p.	NOUN
brainmatters-1083	48	24	,	,	PUNCT
brainmatters-1083	48	25	2019	2019	NUM
brainmatters-1083	48	26	)	)	PUNCT
brainmatters-1083	48	27	research	research	NOUN
brainmatters-1083	48	28	suggests	suggest	VERB
brainmatters-1083	48	29	that	that	SCONJ
brainmatters-1083	48	30	pathogens	pathogen	NOUN
brainmatters-1083	48	31	involved	involve	VERB
brainmatters-1083	48	32	with	with	ADP
brainmatters-1083	48	33	demyelination	demyelination	NOUN
brainmatters-1083	48	34	may	may	AUX
brainmatters-1083	48	35	appear	appear	VERB
brainmatters-1083	48	36	to	to	PART
brainmatters-1083	48	37	be	be	AUX
brainmatters-1083	48	38	similar	similar	ADJ
brainmatters-1083	48	39	to	to	ADP
brainmatters-1083	48	40	the	the	DET
brainmatters-1083	48	41	actual	actual	ADJ
brainmatters-1083	48	42	myelin	myelin	NOUN
brainmatters-1083	48	43	itself	itself	PRON
brainmatters-1083	48	44	.	.	PUNCT
brainmatters-1083	49	1	as	as	ADP
brainmatters-1083	49	2	a	a	DET
brainmatters-1083	49	3	result	result	NOUN
brainmatters-1083	49	4	,	,	PUNCT
brainmatters-1083	49	5	drb1	drb1	PROPN
brainmatters-1083	49	6	*	*	NOUN
brainmatters-1083	49	7	1501	1501	NUM
brainmatters-1083	49	8	could	could	AUX
brainmatters-1083	49	9	be	be	AUX
brainmatters-1083	49	10	especially	especially	ADV
brainmatters-1083	49	11	susceptible	susceptible	ADJ
brainmatters-1083	49	12	to	to	ADP
brainmatters-1083	49	13	being	be	AUX
brainmatters-1083	49	14	“	"	PUNCT
brainmatters-1083	49	15	tricked	trick	VERB
brainmatters-1083	49	16	”	"	PUNCT
brainmatters-1083	49	17	by	by	ADP
brainmatters-1083	49	18	this	this	DET
brainmatters-1083	49	19	mimicry	mimicry	NOUN
brainmatters-1083	49	20	and	and	CCONJ
brainmatters-1083	49	21	produce	produce	VERB
brainmatters-1083	49	22	agents	agent	NOUN
brainmatters-1083	49	23	that	that	PRON
brainmatters-1083	49	24	begin	begin	VERB
brainmatters-1083	49	25	attacking	attack	VERB
brainmatters-1083	49	26	myelin	myelin	NOUN
brainmatters-1083	49	27	instead	instead	ADV
brainmatters-1083	49	28	of	of	ADP
brainmatters-1083	49	29	the	the	DET
brainmatters-1083	49	30	pathogens	pathogen	NOUN
brainmatters-1083	49	31	(	(	PUNCT
brainmatters-1083	49	32	sospedra	sospedra	PROPN
brainmatters-1083	49	33	,	,	PUNCT
brainmatters-1083	49	34	m.	m.	NOUN
brainmatters-1083	49	35	,	,	PUNCT
brainmatters-1083	49	36	&	&	CCONJ
brainmatters-1083	49	37	martin	martin	PROPN
brainmatters-1083	49	38	,	,	PUNCT
brainmatters-1083	49	39	r.	r.	PROPN
brainmatters-1083	49	40	,	,	PUNCT
brainmatters-1083	49	41	2005	2005	NUM
brainmatters-1083	49	42	)	)	PUNCT
brainmatters-1083	49	43	.	.	PUNCT
brainmatters-1083	50	1	in	in	ADP
brainmatters-1083	50	2	addition	addition	NOUN
brainmatters-1083	50	3	,	,	PUNCT
brainmatters-1083	50	4	research	research	NOUN
brainmatters-1083	50	5	shows	show	VERB
brainmatters-1083	50	6	that	that	SCONJ
brainmatters-1083	50	7	drb1	drb1	PROPN
brainmatters-1083	50	8	*	*	NOUN
brainmatters-1083	50	9	1501	1501	NUM
brainmatters-1083	50	10	is	be	AUX
brainmatters-1083	50	11	suspected	suspect	VERB
brainmatters-1083	50	12	to	to	PART
brainmatters-1083	50	13	interact	interact	VERB
brainmatters-1083	50	14	with	with	ADP
brainmatters-1083	50	15	specific	specific	ADJ
brainmatters-1083	50	16	cytokines	cytokine	NOUN
brainmatters-1083	50	17	that	that	PRON
brainmatters-1083	50	18	are	be	AUX
brainmatters-1083	50	19	responsible	responsible	ADJ
brainmatters-1083	50	20	for	for	ADP
brainmatters-1083	50	21	signaling	signal	VERB
brainmatters-1083	50	22	immune	immune	ADJ
brainmatters-1083	50	23	responses	response	NOUN
brainmatters-1083	50	24	in	in	ADP
brainmatters-1083	50	25	the	the	DET
brainmatters-1083	50	26	brain	brain	NOUN
brainmatters-1083	50	27	,	,	PUNCT
brainmatters-1083	50	28	causing	cause	VERB
brainmatters-1083	50	29	inflammation	inflammation	NOUN
brainmatters-1083	50	30	and	and	CCONJ
brainmatters-1083	50	31	degeneration	degeneration	NOUN
brainmatters-1083	50	32	of	of	ADP
brainmatters-1083	50	33	cells	cell	NOUN
brainmatters-1083	50	34	in	in	ADP
brainmatters-1083	50	35	the	the	DET
brainmatters-1083	50	36	cns	cns	NOUN
brainmatters-1083	50	37	.	.	PUNCT
brainmatters-1083	51	1	they	they	PRON
brainmatters-1083	51	2	essentially	essentially	ADV
brainmatters-1083	51	3	secrete	secrete	VERB
brainmatters-1083	51	4	proinflammatory	proinflammatory	ADJ
brainmatters-1083	51	5	cytokines	cytokine	NOUN
brainmatters-1083	51	6	that	that	PRON
brainmatters-1083	51	7	predispose	predispose	VERB
brainmatters-1083	51	8	the	the	DET
brainmatters-1083	51	9	body	body	NOUN
brainmatters-1083	51	10	to	to	ADP
brainmatters-1083	51	11	autoimmune	autoimmune	ADJ
brainmatters-1083	51	12	diseases	disease	NOUN
brainmatters-1083	51	13	such	such	ADJ
brainmatters-1083	51	14	as	as	ADP
brainmatters-1083	51	15	ms	ms	PROPN
brainmatters-1083	51	16	.	.	PROPN
brainmatters-1083	51	17	when	when	SCONJ
brainmatters-1083	51	18	reviewing	review	VERB
brainmatters-1083	51	19	patients	patient	NOUN
brainmatters-1083	51	20	who	who	PRON
brainmatters-1083	51	21	expressed	express	VERB
brainmatters-1083	51	22	a	a	DET
brainmatters-1083	51	23	high	high	ADJ
brainmatters-1083	51	24	frequency	frequency	NOUN
brainmatters-1083	51	25	of	of	ADP
brainmatters-1083	51	26	drb1	drb1	PROPN
brainmatters-1083	51	27	*	*	PROPN
brainmatters-1083	51	28	1501	1501	NUM
brainmatters-1083	51	29	,	,	PUNCT
brainmatters-1083	51	30	scientists	scientist	NOUN
brainmatters-1083	51	31	found	find	VERB
brainmatters-1083	51	32	that	that	SCONJ
brainmatters-1083	51	33	“	"	PUNCT
brainmatters-1083	51	34	carriage	carriage	NOUN
brainmatters-1083	51	35	of	of	ADP
brainmatters-1083	51	36	hla	hla	PROPN
brainmatters-1083	51	37	-	-	PUNCT
brainmatters-1083	51	38	drb1	drb1	PROPN
brainmatters-1083	51	39	*	*	NOUN
brainmatters-1083	51	40	15	15	NUM
brainmatters-1083	51	41	was	be	AUX
brainmatters-1083	51	42	associated	associate	VERB
brainmatters-1083	51	43	with	with	ADP
brainmatters-1083	51	44	increases	increase	NOUN
brainmatters-1083	51	45	in	in	ADP
brainmatters-1083	51	46	the	the	DET
brainmatters-1083	51	47	development	development	NOUN
brainmatters-1083	51	48	of	of	ADP
brainmatters-1083	51	49	brain	brain	NOUN
brainmatters-1083	51	50	grey	grey	NOUN
brainmatters-1083	51	51	and	and	CCONJ
brainmatters-1083	51	52	white	white	ADJ
brainmatters-1083	51	53	matter	matter	NOUN
brainmatters-1083	51	54	pathology	pathology	NOUN
brainmatters-1083	51	55	,	,	PUNCT
brainmatters-1083	51	56	as	as	SCONJ
brainmatters-1083	51	57	reflected	reflect	VERB
brainmatters-1083	51	58	by	by	ADP
brainmatters-1083	51	59	reduced	reduce	VERB
brainmatters-1083	51	60	[	[	X
brainmatters-1083	51	61	magnetization	magnetization	NOUN
brainmatters-1083	51	62	transfer	transfer	NOUN
brainmatters-1083	51	63	ratio	ratio	NOUN
brainmatters-1083	51	64	]	]	PUNCT
brainmatters-1083	51	65	(	(	PUNCT
brainmatters-1083	51	66	mtr	mtr	NOUN
brainmatters-1083	51	67	)	)	PUNCT
brainmatters-1083	51	68	,	,	PUNCT
brainmatters-1083	51	69	a	a	DET
brainmatters-1083	51	70	trend	trend	NOUN
brainmatters-1083	51	71	toward	toward	ADP
brainmatters-1083	51	72	increased	increase	VERB
brainmatters-1083	51	73	t2	t2	NOUN
brainmatters-1083	51	74	lesion	lesion	NOUN
brainmatters-1083	51	75	load	load	NOUN
brainmatters-1083	51	76	over	over	ADP
brainmatters-1083	51	77	5	5	NUM
brainmatters-1083	51	78	years	year	NOUN
brainmatters-1083	51	79	,	,	PUNCT
brainmatters-1083	51	80	and	and	CCONJ
brainmatters-1083	51	81	greater	great	ADJ
brainmatters-1083	51	82	t2	t2	NOUN
brainmatters-1083	51	83	lesion	lesion	NOUN
brainmatters-1083	51	84	volumes	volume	NOUN
brainmatters-1083	51	85	at	at	ADP
brainmatters-1083	51	86	each	each	DET
brainmatters-1083	51	87	time	time	NOUN
brainmatters-1083	51	88	point	point	NOUN
brainmatters-1083	51	89	over	over	ADP
brainmatters-1083	51	90	the	the	DET
brainmatters-1083	51	91	follow	follow	NOUN
brainmatters-1083	51	92	-	-	PUNCT
brainmatters-1083	51	93	up	up	NOUN
brainmatters-1083	51	94	”	"	PUNCT
brainmatters-1083	51	95	(	(	PUNCT
brainmatters-1083	51	96	tur	tur	INTJ
brainmatters-1083	51	97	,	,	PUNCT
brainmatters-1083	51	98	c.	c.	NOUN
brainmatters-1083	51	99	,	,	PUNCT
brainmatters-1083	51	100	ramagopalan	ramagopalan	NOUN
brainmatters-1083	51	101	,	,	PUNCT
brainmatters-1083	51	102	s.	s.	PROPN
brainmatters-1083	51	103	,	,	PUNCT
brainmatters-1083	51	104	altmann	altmann	PROPN
brainmatters-1083	51	105	,	,	PUNCT
brainmatters-1083	51	106	d.	d.	PROPN
brainmatters-1083	51	107	r.	r.	PROPN
brainmatters-1083	51	108	,	,	PUNCT
brainmatters-1083	51	109	et	et	PROPN
brainmatters-1083	51	110	al	al	PROPN
brainmatters-1083	51	111	.	.	PROPN
brainmatters-1083	51	112	,	,	PUNCT
brainmatters-1083	51	113	2014	2014	NUM
brainmatters-1083	51	114	)	)	PUNCT
brainmatters-1083	51	115	.	.	PUNCT
brainmatters-1083	52	1	thus	thus	ADV
brainmatters-1083	52	2	,	,	PUNCT
brainmatters-1083	52	3	it	it	PRON
brainmatters-1083	52	4	was	be	AUX
brainmatters-1083	52	5	concluded	conclude	VERB
brainmatters-1083	52	6	that	that	SCONJ
brainmatters-1083	52	7	individuals	individual	NOUN
brainmatters-1083	52	8	showed	show	VERB
brainmatters-1083	52	9	a	a	DET
brainmatters-1083	52	10	significant	significant	ADJ
brainmatters-1083	52	11	amount	amount	NOUN
brainmatters-1083	52	12	of	of	ADP
brainmatters-1083	52	13	brain	brain	NOUN
brainmatters-1083	52	14	atrophy	atrophy	NOUN
brainmatters-1083	52	15	when	when	SCONJ
brainmatters-1083	52	16	contrasted	contrast	VERB
brainmatters-1083	52	17	with	with	ADP
brainmatters-1083	52	18	the	the	DET
brainmatters-1083	52	19	healthy	healthy	ADJ
brainmatters-1083	52	20	control	control	NOUN
brainmatters-1083	52	21	group	group	NOUN
brainmatters-1083	52	22	.	.	PUNCT
brainmatters-1083	53	1	this	this	PRON
brainmatters-1083	53	2	shows	show	VERB
brainmatters-1083	53	3	a	a	DET
brainmatters-1083	53	4	strong	strong	ADJ
brainmatters-1083	53	5	positive	positive	ADJ
brainmatters-1083	53	6	correlation	correlation	NOUN
brainmatters-1083	53	7	between	between	ADP
brainmatters-1083	53	8	the	the	DET
brainmatters-1083	53	9	presence	presence	NOUN
brainmatters-1083	53	10	of	of	ADP
brainmatters-1083	53	11	the	the	DET
brainmatters-1083	53	12	drb1	drb1	PROPN
brainmatters-1083	53	13	*	*	PROPN
brainmatters-1083	53	14	1501	1501	NUM
brainmatters-1083	53	15	allele	allele	NOUN
brainmatters-1083	53	16	and	and	CCONJ
brainmatters-1083	53	17	abnormal	abnormal	ADJ
brainmatters-1083	53	18	amounts	amount	NOUN
brainmatters-1083	53	19	of	of	ADP
brainmatters-1083	53	20	atrophy	atrophy	NOUN
brainmatters-1083	53	21	in	in	ADP
brainmatters-1083	53	22	the	the	DET
brainmatters-1083	53	23	brain	brain	NOUN
brainmatters-1083	53	24	.	.	PUNCT
brainmatters-1083	54	1	brain	brain	NOUN
brainmatters-1083	54	2	matters	matter	NOUN
brainmatters-1083	54	3	vol	vol	NOUN
brainmatters-1083	54	4	.	.	PROPN
brainmatters-1083	54	5	8	8	NUM
brainmatters-1083	54	6	2025	2025	NUM
brainmatters-1083	54	7	effects	effect	NOUN
brainmatters-1083	54	8	of	of	ADP
brainmatters-1083	54	9	hla	hla	NOUN
brainmatters-1083	54	10	on	on	ADP
brainmatters-1083	54	11	the	the	DET
brainmatters-1083	54	12	pathways	pathway	NOUN
brainmatters-1083	54	13	of	of	ADP
brainmatters-1083	54	14	ms	ms	PROPN
brainmatters-1083	54	15	and	and	CCONJ
brainmatters-1083	54	16	ba	ba	PROPN
brainmatters-1083	54	17	in	in	ADP
brainmatters-1083	54	18	nearly	nearly	ADV
brainmatters-1083	54	19	every	every	PRON
brainmatters-1083	54	20	case	case	NOUN
brainmatters-1083	54	21	of	of	ADP
brainmatters-1083	54	22	ms	ms	PROPN
brainmatters-1083	54	23	,	,	PUNCT
brainmatters-1083	54	24	the	the	DET
brainmatters-1083	54	25	early	early	ADJ
brainmatters-1083	54	26	stages	stage	NOUN
brainmatters-1083	54	27	of	of	ADP
brainmatters-1083	54	28	pathology	pathology	NOUN
brainmatters-1083	54	29	result	result	NOUN
brainmatters-1083	54	30	from	from	ADP
brainmatters-1083	54	31	abnormal	abnormal	ADJ
brainmatters-1083	54	32	amounts	amount	NOUN
brainmatters-1083	54	33	of	of	ADP
brainmatters-1083	54	34	inflammation	inflammation	NOUN
brainmatters-1083	54	35	in	in	ADP
brainmatters-1083	54	36	the	the	DET
brainmatters-1083	54	37	brain	brain	NOUN
brainmatters-1083	54	38	(	(	PUNCT
brainmatters-1083	54	39	kiss	kiss	PROPN
brainmatters-1083	54	40	,	,	PUNCT
brainmatters-1083	54	41	m.	m.	NOUN
brainmatters-1083	54	42	&	&	CCONJ
brainmatters-1083	54	43	mcalpine	mcalpine	PROPN
brainmatters-1083	54	44	,	,	PUNCT
brainmatters-1083	54	45	c.s	c.s	PROPN
brainmatters-1083	54	46	.	.	PROPN
brainmatters-1083	54	47	,	,	PUNCT
brainmatters-1083	54	48	2023	2023	NUM
brainmatters-1083	54	49	)	)	PUNCT
brainmatters-1083	54	50	.	.	PUNCT
brainmatters-1083	55	1	neuroinflammation	neuroinflammation	NOUN
brainmatters-1083	55	2	is	be	AUX
brainmatters-1083	55	3	caused	cause	VERB
brainmatters-1083	55	4	by	by	ADP
brainmatters-1083	55	5	the	the	DET
brainmatters-1083	55	6	increased	increase	VERB
brainmatters-1083	55	7	presence	presence	NOUN
brainmatters-1083	55	8	of	of	ADP
brainmatters-1083	55	9	t	t	PROPN
brainmatters-1083	55	10	-	-	PUNCT
brainmatters-1083	55	11	cells	cell	NOUN
brainmatters-1083	55	12	in	in	ADP
brainmatters-1083	55	13	response	response	NOUN
brainmatters-1083	55	14	to	to	ADP
brainmatters-1083	55	15	supposed	suppose	VERB
brainmatters-1083	55	16	invaders	invader	NOUN
brainmatters-1083	55	17	,	,	PUNCT
brainmatters-1083	55	18	which	which	PRON
brainmatters-1083	55	19	in	in	ADP
brainmatters-1083	55	20	cases	case	NOUN
brainmatters-1083	55	21	of	of	ADP
brainmatters-1083	55	22	ms	ms	NOUN
brainmatters-1083	55	23	are	be	AUX
brainmatters-1083	55	24	the	the	DET
brainmatters-1083	55	25	body	body	NOUN
brainmatters-1083	55	26	’s	’s	PART
brainmatters-1083	55	27	own	own	ADJ
brainmatters-1083	55	28	cells	cell	NOUN
brainmatters-1083	55	29	,	,	PUNCT
brainmatters-1083	55	30	and	and	CCONJ
brainmatters-1083	55	31	the	the	DET
brainmatters-1083	55	32	regulation	regulation	NOUN
brainmatters-1083	55	33	of	of	ADP
brainmatters-1083	55	34	these	these	DET
brainmatters-1083	55	35	t	t	NOUN
brainmatters-1083	55	36	-	-	PUNCT
brainmatters-1083	55	37	cells	cell	NOUN
brainmatters-1083	55	38	is	be	AUX
brainmatters-1083	55	39	linked	link	VERB
brainmatters-1083	55	40	back	back	ADV
brainmatters-1083	55	41	to	to	ADP
brainmatters-1083	55	42	hla	hla	PROPN
brainmatters-1083	55	43	.	.	PUNCT
brainmatters-1083	56	1	individuals	individual	NOUN
brainmatters-1083	56	2	carrying	carry	VERB
brainmatters-1083	56	3	the	the	DET
brainmatters-1083	56	4	drb1	drb1	PROPN
brainmatters-1083	56	5	*	*	SYM
brainmatters-1083	56	6	1501	1501	NUM
brainmatters-1083	56	7	allele	allele	NOUN
brainmatters-1083	56	8	,	,	PUNCT
brainmatters-1083	56	9	have	have	VERB
brainmatters-1083	56	10	an	an	DET
brainmatters-1083	56	11	increased	increase	VERB
brainmatters-1083	56	12	susceptibility	susceptibility	NOUN
brainmatters-1083	56	13	to	to	ADP
brainmatters-1083	56	14	ms	ms	NOUN
brainmatters-1083	56	15	and	and	CCONJ
brainmatters-1083	56	16	more	more	ADV
brainmatters-1083	56	17	severe	severe	ADJ
brainmatters-1083	56	18	disease	disease	NOUN
brainmatters-1083	56	19	progression	progression	NOUN
brainmatters-1083	56	20	,	,	PUNCT
brainmatters-1083	56	21	which	which	PRON
brainmatters-1083	56	22	can	can	AUX
brainmatters-1083	56	23	lead	lead	VERB
brainmatters-1083	56	24	to	to	ADP
brainmatters-1083	56	25	greater	great	ADJ
brainmatters-1083	56	26	demyelination	demyelination	NOUN
brainmatters-1083	56	27	.	.	PUNCT
brainmatters-1083	57	1	this	this	PRON
brainmatters-1083	57	2	is	be	AUX
brainmatters-1083	57	3	due	due	ADJ
brainmatters-1083	57	4	to	to	ADP
brainmatters-1083	57	5	the	the	DET
brainmatters-1083	57	6	role	role	NOUN
brainmatters-1083	57	7	of	of	ADP
brainmatters-1083	57	8	these	these	DET
brainmatters-1083	57	9	alleles	allele	NOUN
brainmatters-1083	57	10	in	in	ADP
brainmatters-1083	57	11	promoting	promote	VERB
brainmatters-1083	57	12	an	an	DET
brainmatters-1083	57	13	autoimmune	autoimmune	ADJ
brainmatters-1083	57	14	response	response	NOUN
brainmatters-1083	57	15	against	against	ADP
brainmatters-1083	57	16	myelin	myelin	ADJ
brainmatters-1083	57	17	proteins	protein	NOUN
brainmatters-1083	57	18	.	.	PUNCT
brainmatters-1083	58	1	similarly	similarly	ADV
brainmatters-1083	58	2	,	,	PUNCT
brainmatters-1083	58	3	the	the	DET
brainmatters-1083	58	4	onset	onset	NOUN
brainmatters-1083	58	5	of	of	ADP
brainmatters-1083	58	6	ba	ba	PROPN
brainmatters-1083	58	7	is	be	AUX
brainmatters-1083	58	8	caused	cause	VERB
brainmatters-1083	58	9	by	by	ADP
brainmatters-1083	58	10	abnormal	abnormal	ADJ
brainmatters-1083	58	11	amounts	amount	NOUN
brainmatters-1083	58	12	of	of	ADP
brainmatters-1083	58	13	demyelination	demyelination	NOUN
brainmatters-1083	58	14	in	in	ADP
brainmatters-1083	58	15	the	the	DET
brainmatters-1083	58	16	brain	brain	NOUN
brainmatters-1083	58	17	.	.	PUNCT
brainmatters-1083	59	1	one	one	NUM
brainmatters-1083	59	2	of	of	ADP
brainmatters-1083	59	3	the	the	DET
brainmatters-1083	59	4	most	most	ADV
brainmatters-1083	59	5	common	common	ADJ
brainmatters-1083	59	6	causes	cause	NOUN
brainmatters-1083	59	7	of	of	ADP
brainmatters-1083	59	8	demyelination	demyelination	NOUN
brainmatters-1083	59	9	is	be	AUX
brainmatters-1083	59	10	inflammation	inflammation	NOUN
brainmatters-1083	59	11	,	,	PUNCT
brainmatters-1083	59	12	linking	link	VERB
brainmatters-1083	59	13	the	the	DET
brainmatters-1083	59	14	root	root	NOUN
brainmatters-1083	59	15	cause	cause	NOUN
brainmatters-1083	59	16	of	of	ADP
brainmatters-1083	59	17	ba	ba	NOUN
brainmatters-1083	59	18	to	to	ADP
brainmatters-1083	59	19	the	the	DET
brainmatters-1083	59	20	root	root	NOUN
brainmatters-1083	59	21	cause	cause	NOUN
brainmatters-1083	59	22	of	of	ADP
brainmatters-1083	59	23	ms	ms	PROPN
brainmatters-1083	59	24	.	.	PROPN
brainmatters-1083	59	25	thus	thus	ADV
brainmatters-1083	59	26	,	,	PUNCT
brainmatters-1083	59	27	ba	ba	PROPN
brainmatters-1083	59	28	is	be	AUX
brainmatters-1083	59	29	similarly	similarly	ADV
brainmatters-1083	59	30	influenced	influence	VERB
brainmatters-1083	59	31	by	by	ADP
brainmatters-1083	59	32	the	the	DET
brainmatters-1083	59	33	hla	hla	PROPN
brainmatters-1083	59	34	alleles	allele	NOUN
brainmatters-1083	59	35	.	.	PUNCT
brainmatters-1083	60	1	conclusion	conclusion	NOUN
brainmatters-1083	60	2	although	although	SCONJ
brainmatters-1083	60	3	the	the	DET
brainmatters-1083	60	4	significance	significance	NOUN
brainmatters-1083	60	5	of	of	ADP
brainmatters-1083	60	6	hla	hla	PROPN
brainmatters-1083	60	7	on	on	ADP
brainmatters-1083	60	8	the	the	DET
brainmatters-1083	60	9	pathways	pathway	NOUN
brainmatters-1083	60	10	of	of	ADP
brainmatters-1083	60	11	ba	ba	PROPN
brainmatters-1083	60	12	and	and	CCONJ
brainmatters-1083	60	13	ms	ms	PROPN
brainmatters-1083	60	14	has	have	AUX
brainmatters-1083	60	15	not	not	PART
brainmatters-1083	60	16	been	be	AUX
brainmatters-1083	60	17	widely	widely	ADV
brainmatters-1083	60	18	explored	explore	VERB
brainmatters-1083	60	19	,	,	PUNCT
brainmatters-1083	60	20	the	the	DET
brainmatters-1083	60	21	link	link	NOUN
brainmatters-1083	60	22	between	between	ADP
brainmatters-1083	60	23	the	the	DET
brainmatters-1083	60	24	two	two	NUM
brainmatters-1083	60	25	is	be	AUX
brainmatters-1083	60	26	most	most	ADV
brainmatters-1083	60	27	certainly	certainly	ADV
brainmatters-1083	60	28	present	present	ADJ
brainmatters-1083	60	29	.	.	PUNCT
brainmatters-1083	61	1	due	due	ADP
brainmatters-1083	61	2	to	to	ADP
brainmatters-1083	61	3	both	both	DET
brainmatters-1083	61	4	neurodegenerative	neurodegenerative	ADJ
brainmatters-1083	61	5	diseases	disease	NOUN
brainmatters-1083	61	6	being	be	AUX
brainmatters-1083	61	7	directly	directly	ADV
brainmatters-1083	61	8	linked	link	VERB
brainmatters-1083	61	9	to	to	ADP
brainmatters-1083	61	10	the	the	DET
brainmatters-1083	61	11	loss	loss	NOUN
brainmatters-1083	61	12	of	of	ADP
brainmatters-1083	61	13	synapses	synapsis	NOUN
brainmatters-1083	61	14	onset	onset	VERB
brainmatters-1083	61	15	by	by	ADP
brainmatters-1083	61	16	autoimmune	autoimmune	ADJ
brainmatters-1083	61	17	responses	response	NOUN
brainmatters-1083	61	18	in	in	ADP
brainmatters-1083	61	19	the	the	DET
brainmatters-1083	61	20	brain	brain	NOUN
brainmatters-1083	61	21	,	,	PUNCT
brainmatters-1083	61	22	and	and	CCONJ
brainmatters-1083	61	23	hla	hla	NOUN
brainmatters-1083	61	24	being	be	AUX
brainmatters-1083	61	25	responsible	responsible	ADJ
brainmatters-1083	61	26	for	for	ADP
brainmatters-1083	61	27	the	the	DET
brainmatters-1083	61	28	immune	immune	ADJ
brainmatters-1083	61	29	system	system	NOUN
brainmatters-1083	61	30	,	,	PUNCT
brainmatters-1083	61	31	hla	hla	PROPN
brainmatters-1083	61	32	is	be	AUX
brainmatters-1083	61	33	a	a	DET
brainmatters-1083	61	34	clear	clear	ADJ
brainmatters-1083	61	35	factor	factor	NOUN
brainmatters-1083	61	36	in	in	ADP
brainmatters-1083	61	37	the	the	DET
brainmatters-1083	61	38	development	development	NOUN
brainmatters-1083	61	39	of	of	ADP
brainmatters-1083	61	40	ba	ba	PROPN
brainmatters-1083	61	41	and	and	CCONJ
brainmatters-1083	61	42	ms	ms	PROPN
brainmatters-1083	61	43	.	.	PROPN
brainmatters-1083	62	1	the	the	DET
brainmatters-1083	62	2	two	two	NUM
brainmatters-1083	62	3	alleles	allele	NOUN
brainmatters-1083	62	4	most	most	ADV
brainmatters-1083	62	5	closely	closely	ADV
brainmatters-1083	62	6	related	relate	VERB
brainmatters-1083	62	7	to	to	ADP
brainmatters-1083	62	8	the	the	DET
brainmatters-1083	62	9	onset	onset	NOUN
brainmatters-1083	62	10	of	of	ADP
brainmatters-1083	62	11	the	the	DET
brainmatters-1083	62	12	diseases	disease	NOUN
brainmatters-1083	62	13	,	,	PUNCT
brainmatters-1083	62	14	drb1	drb1	PROPN
brainmatters-1083	62	15	*	*	PROPN
brainmatters-1083	62	16	1501	1501	NUM
brainmatters-1083	62	17	and	and	CCONJ
brainmatters-1083	62	18	drb1	drb1	PROPN
brainmatters-1083	62	19	*	*	PROPN
brainmatters-1083	62	20	1302	1302	NUM
brainmatters-1083	62	21	,	,	PUNCT
brainmatters-1083	62	22	are	be	AUX
brainmatters-1083	62	23	haploids	haploid	NOUN
brainmatters-1083	62	24	of	of	ADP
brainmatters-1083	62	25	hla	hla	NOUN
brainmatters-1083	62	26	,	,	PUNCT
brainmatters-1083	62	27	so	so	ADV
brainmatters-1083	62	28	genomic	genomic	ADJ
brainmatters-1083	62	29	editing	editing	NOUN
brainmatters-1083	62	30	and	and	CCONJ
brainmatters-1083	62	31	therapy	therapy	NOUN
brainmatters-1083	62	32	may	may	AUX
brainmatters-1083	62	33	provide	provide	VERB
brainmatters-1083	62	34	the	the	DET
brainmatters-1083	62	35	first	first	ADJ
brainmatters-1083	62	36	preventative	preventative	ADJ
brainmatters-1083	62	37	cure	cure	NOUN
brainmatters-1083	62	38	for	for	ADP
brainmatters-1083	62	39	ba	ba	PROPN
brainmatters-1083	62	40	and	and	CCONJ
brainmatters-1083	62	41	ms	ms	PROPN
brainmatters-1083	62	42	.	.	PROPN
brainmatters-1083	62	43	proposed	propose	VERB
brainmatters-1083	62	44	preventative	preventative	ADJ
brainmatters-1083	62	45	gene	gene	NOUN
brainmatters-1083	62	46	therapy	therapy	NOUN
brainmatters-1083	62	47	:	:	PUNCT
brainmatters-1083	62	48	brain	brain	NOUN
brainmatters-1083	62	49	atrophy	atrophy	NOUN
brainmatters-1083	62	50	and	and	CCONJ
brainmatters-1083	62	51	multiple	multiple	ADJ
brainmatters-1083	62	52	sclerosis	sclerosis	NOUN
brainmatters-1083	62	53	have	have	AUX
brainmatters-1083	62	54	long	long	ADV
brainmatters-1083	62	55	been	be	AUX
brainmatters-1083	62	56	thought	think	VERB
brainmatters-1083	62	57	to	to	PART
brainmatters-1083	62	58	be	be	AUX
brainmatters-1083	62	59	incurable	incurable	ADJ
brainmatters-1083	62	60	,	,	PUNCT
brainmatters-1083	62	61	with	with	ADP
brainmatters-1083	62	62	treatment	treatment	NOUN
brainmatters-1083	62	63	mainly	mainly	ADV
brainmatters-1083	62	64	consisting	consist	VERB
brainmatters-1083	62	65	of	of	ADP
brainmatters-1083	62	66	just	just	ADV
brainmatters-1083	62	67	improving	improve	VERB
brainmatters-1083	62	68	the	the	DET
brainmatters-1083	62	69	quality	quality	NOUN
brainmatters-1083	62	70	of	of	ADP
brainmatters-1083	62	71	life	life	NOUN
brainmatters-1083	62	72	of	of	ADP
brainmatters-1083	62	73	people	people	NOUN
brainmatters-1083	62	74	afflicted	afflict	VERB
brainmatters-1083	62	75	with	with	ADP
brainmatters-1083	62	76	these	these	DET
brainmatters-1083	62	77	diseases	disease	NOUN
brainmatters-1083	62	78	.	.	PUNCT
brainmatters-1083	63	1	since	since	SCONJ
brainmatters-1083	63	2	different	different	ADJ
brainmatters-1083	63	3	alleles	allele	NOUN
brainmatters-1083	63	4	of	of	ADP
brainmatters-1083	63	5	hla	hla	NOUN
brainmatters-1083	63	6	can	can	AUX
brainmatters-1083	63	7	produce	produce	VERB
brainmatters-1083	63	8	different	different	ADJ
brainmatters-1083	63	9	effects	effect	NOUN
brainmatters-1083	63	10	on	on	ADP
brainmatters-1083	63	11	ba	ba	PROPN
brainmatters-1083	63	12	and	and	CCONJ
brainmatters-1083	63	13	ms	ms	PROPN
brainmatters-1083	63	14	,	,	PUNCT
brainmatters-1083	63	15	a	a	DET
brainmatters-1083	63	16	potential	potential	ADJ
brainmatters-1083	63	17	goal	goal	NOUN
brainmatters-1083	63	18	for	for	ADP
brainmatters-1083	63	19	gene	gene	NOUN
brainmatters-1083	63	20	therapy	therapy	NOUN
brainmatters-1083	63	21	could	could	AUX
brainmatters-1083	63	22	be	be	AUX
brainmatters-1083	63	23	to	to	PART
brainmatters-1083	63	24	activate	activate	VERB
brainmatters-1083	63	25	drb1	drb1	PROPN
brainmatters-1083	63	26	*	*	NOUN
brainmatters-1083	63	27	1302	1302	NUM
brainmatters-1083	63	28	more	more	ADV
brainmatters-1083	63	29	often	often	ADV
brainmatters-1083	63	30	and	and	CCONJ
brainmatters-1083	63	31	suppress	suppress	VERB
brainmatters-1083	63	32	the	the	DET
brainmatters-1083	63	33	expression	expression	NOUN
brainmatters-1083	63	34	of	of	ADP
brainmatters-1083	63	35	drb1	drb1	PROPN
brainmatters-1083	63	36	*	*	NOUN
brainmatters-1083	63	37	1501	1501	NUM
brainmatters-1083	63	38	in	in	ADP
brainmatters-1083	63	39	hla	hla	PROPN
brainmatters-1083	63	40	.	.	PUNCT
brainmatters-1083	64	1	as	as	ADP
brainmatters-1083	64	2	a	a	DET
brainmatters-1083	64	3	result	result	NOUN
brainmatters-1083	64	4	,	,	PUNCT
brainmatters-1083	64	5	preventative	preventative	ADJ
brainmatters-1083	64	6	effects	effect	NOUN
brainmatters-1083	64	7	would	would	AUX
brainmatters-1083	64	8	be	be	AUX
brainmatters-1083	64	9	much	much	ADV
brainmatters-1083	64	10	higher	high	ADJ
brainmatters-1083	64	11	,	,	PUNCT
brainmatters-1083	64	12	and	and	CCONJ
brainmatters-1083	64	13	the	the	DET
brainmatters-1083	64	14	rate	rate	NOUN
brainmatters-1083	64	15	of	of	ADP
brainmatters-1083	64	16	ba	ba	PROPN
brainmatters-1083	64	17	and	and	CCONJ
brainmatters-1083	64	18	ms	ms	PROPN
brainmatters-1083	64	19	in	in	ADP
brainmatters-1083	64	20	individuals	individual	NOUN
brainmatters-1083	64	21	would	would	AUX
brainmatters-1083	64	22	likely	likely	ADV
brainmatters-1083	64	23	decrease	decrease	VERB
brainmatters-1083	64	24	significantly	significantly	ADV
brainmatters-1083	64	25	.	.	PUNCT
brainmatters-1083	65	1	one	one	NUM
brainmatters-1083	65	2	form	form	NOUN
brainmatters-1083	65	3	of	of	ADP
brainmatters-1083	65	4	gene	gene	NOUN
brainmatters-1083	65	5	therapy	therapy	NOUN
brainmatters-1083	65	6	could	could	AUX
brainmatters-1083	65	7	focus	focus	VERB
brainmatters-1083	65	8	on	on	ADP
brainmatters-1083	65	9	monoallelic	monoallelic	ADJ
brainmatters-1083	65	10	expression	expression	NOUN
brainmatters-1083	65	11	,	,	PUNCT
brainmatters-1083	65	12	as	as	SCONJ
brainmatters-1083	65	13	demonstrated	demonstrate	VERB
brainmatters-1083	65	14	in	in	ADP
brainmatters-1083	65	15	figure	figure	NOUN
brainmatters-1083	65	16	4	4	NUM
brainmatters-1083	65	17	,	,	PUNCT
brainmatters-1083	65	18	which	which	PRON
brainmatters-1083	65	19	is	be	AUX
brainmatters-1083	65	20	when	when	SCONJ
brainmatters-1083	65	21	one	one	NUM
brainmatters-1083	65	22	allele	allele	NOUN
brainmatters-1083	65	23	of	of	ADP
brainmatters-1083	65	24	a	a	DET
brainmatters-1083	65	25	gene	gene	NOUN
brainmatters-1083	65	26	is	be	AUX
brainmatters-1083	65	27	expressed	express	VERB
brainmatters-1083	65	28	,	,	PUNCT
brainmatters-1083	65	29	and	and	CCONJ
brainmatters-1083	65	30	another	another	DET
brainmatters-1083	65	31	allele	allele	NOUN
brainmatters-1083	65	32	of	of	ADP
brainmatters-1083	65	33	that	that	DET
brainmatters-1083	65	34	same	same	ADJ
brainmatters-1083	65	35	gene	gene	NOUN
brainmatters-1083	65	36	is	be	AUX
brainmatters-1083	65	37	silenced	silence	VERB
brainmatters-1083	65	38	.	.	PUNCT
brainmatters-1083	66	1	techniques	technique	NOUN
brainmatters-1083	66	2	such	such	ADJ
brainmatters-1083	66	3	as	as	ADP
brainmatters-1083	66	4	crispr	crispr	PROPN
brainmatters-1083	66	5	have	have	AUX
brainmatters-1083	66	6	been	be	AUX
brainmatters-1083	66	7	used	use	VERB
brainmatters-1083	66	8	to	to	PART
brainmatters-1083	66	9	selectively	selectively	ADV
brainmatters-1083	66	10	silence	silence	VERB
brainmatters-1083	66	11	one	one	NUM
brainmatters-1083	66	12	allele	allele	NOUN
brainmatters-1083	66	13	while	while	SCONJ
brainmatters-1083	66	14	leaving	leave	VERB
brainmatters-1083	66	15	the	the	DET
brainmatters-1083	66	16	other	other	ADJ
brainmatters-1083	66	17	intact	intact	ADJ
brainmatters-1083	66	18	,	,	PUNCT
brainmatters-1083	66	19	which	which	PRON
brainmatters-1083	66	20	seems	seem	VERB
brainmatters-1083	66	21	to	to	PART
brainmatters-1083	66	22	be	be	AUX
brainmatters-1083	66	23	exactly	exactly	ADV
brainmatters-1083	66	24	what	what	PRON
brainmatters-1083	66	25	individuals	individual	NOUN
brainmatters-1083	66	26	at	at	ADP
brainmatters-1083	66	27	risk	risk	NOUN
brainmatters-1083	66	28	for	for	ADP
brainmatters-1083	66	29	atrophy	atrophy	NOUN
brainmatters-1083	66	30	need	need	NOUN
brainmatters-1083	66	31	(	(	PUNCT
brainmatters-1083	66	32	hsu	hsu	PROPN
brainmatters-1083	66	33	,	,	PUNCT
brainmatters-1083	66	34	p.	p.	PROPN
brainmatters-1083	66	35	d.	d.	PROPN
brainmatters-1083	66	36	,	,	PUNCT
brainmatters-1083	66	37	lander	lander	PROPN
brainmatters-1083	66	38	,	,	PUNCT
brainmatters-1083	66	39	e.	e.	PROPN
brainmatters-1083	66	40	s.	s.	PROPN
brainmatters-1083	66	41	,	,	PUNCT
brainmatters-1083	66	42	&	&	CCONJ
brainmatters-1083	66	43	zhang	zhang	PROPN
brainmatters-1083	66	44	,	,	PUNCT
brainmatters-1083	66	45	f.	f.	PROPN
brainmatters-1083	66	46	,	,	PUNCT
brainmatters-1083	66	47	2014	2014	NUM
brainmatters-1083	66	48	)	)	PUNCT
brainmatters-1083	66	49	.	.	PUNCT
brainmatters-1083	67	1	overall	overall	ADV
brainmatters-1083	67	2	,	,	PUNCT
brainmatters-1083	67	3	a	a	DET
brainmatters-1083	67	4	preventative	preventative	ADJ
brainmatters-1083	67	5	cure	cure	NOUN
brainmatters-1083	67	6	for	for	ADP
brainmatters-1083	67	7	atrophy	atrophy	NOUN
brainmatters-1083	67	8	may	may	AUX
brainmatters-1083	67	9	be	be	AUX
brainmatters-1083	67	10	just	just	ADV
brainmatters-1083	67	11	around	around	ADP
brainmatters-1083	67	12	the	the	DET
brainmatters-1083	67	13	corner	corner	NOUN
brainmatters-1083	67	14	,	,	PUNCT
brainmatters-1083	67	15	providing	provide	VERB
brainmatters-1083	67	16	a	a	DET
brainmatters-1083	67	17	means	mean	NOUN
brainmatters-1083	67	18	to	to	PART
brainmatters-1083	67	19	protect	protect	VERB
brainmatters-1083	67	20	against	against	ADP
brainmatters-1083	67	21	one	one	NUM
brainmatters-1083	67	22	of	of	ADP
brainmatters-1083	67	23	the	the	DET
brainmatters-1083	67	24	most	most	ADV
brainmatters-1083	67	25	complicated	complicated	ADJ
brainmatters-1083	67	26	and	and	CCONJ
brainmatters-1083	67	27	unstoppable	unstoppable	ADJ
brainmatters-1083	67	28	neurodegenerative	neurodegenerative	ADJ
brainmatters-1083	67	29	effects	effect	NOUN
brainmatters-1083	67	30	.	.	PUNCT
brainmatters-1083	68	1	8	8	NUM
brainmatters-1083	68	2	figure	figure	NOUN
brainmatters-1083	68	3	3	3	NUM
brainmatters-1083	68	4	:	:	PUNCT
brainmatters-1083	68	5	binding	bind	VERB
brainmatters-1083	68	6	motif	motif	NOUN
brainmatters-1083	68	7	of	of	ADP
brainmatters-1083	68	8	hla	hla	PROPN
brainmatters-1083	68	9	drb1	drb1	PROPN
brainmatters-1083	68	10	*	*	PROPN
brainmatters-1083	68	11	1501	1501	NUM
brainmatters-1083	68	12	(	(	PUNCT
brainmatters-1083	68	13	hla	hla	NOUN
brainmatters-1083	68	14	protein	protein	NOUN
brainmatters-1083	68	15	,	,	PUNCT
brainmatters-1083	68	16	2024	2024	NUM
brainmatters-1083	68	17	)	)	PUNCT
brainmatters-1083	68	18	.	.	PUNCT
brainmatters-1083	69	1	figure	figure	VERB
brainmatters-1083	69	2	4	4	NUM
brainmatters-1083	69	3	:	:	PUNCT
brainmatters-1083	69	4	diagram	diagram	NOUN
brainmatters-1083	69	5	of	of	ADP
brainmatters-1083	69	6	monoallelic	monoallelic	ADJ
brainmatters-1083	69	7	gene	gene	NOUN
brainmatters-1083	69	8	therapy	therapy	NOUN
brainmatters-1083	69	9	(	(	PUNCT
brainmatters-1083	69	10	eckersley	eckersley	NOUN
brainmatters-1083	69	11	-	-	PUNCT
brainmatters-1083	69	12	maslin	maslin	NOUN
brainmatters-1083	69	13	,	,	PUNCT
brainmatters-1083	69	14	m.	m.	NOUN
brainmatters-1083	69	15	a.	a.	PROPN
brainmatters-1083	69	16	,	,	PUNCT
brainmatters-1083	69	17	&	&	CCONJ
brainmatters-1083	69	18	spector	spector	PROPN
brainmatters-1083	69	19	,	,	PUNCT
brainmatters-1083	69	20	d.	d.	PROPN
brainmatters-1083	69	21	l.	l.	PROPN
brainmatters-1083	69	22	,	,	PUNCT
brainmatters-1083	69	23	2014	2014	NUM
brainmatters-1083	69	24	)	)	PUNCT
brainmatters-1083	69	25	9	9	NUM
brainmatters-1083	69	26	.	.	X
brainmatters-1083	69	27	pichler	pichler	NOUN
brainmatters-1083	69	28	,	,	PUNCT
brainmatters-1083	69	29	w.	w.	PROPN
brainmatters-1083	69	30	j.	j.	PROPN
brainmatters-1083	69	31	,	,	PUNCT
brainmatters-1083	69	32	&	&	CCONJ
brainmatters-1083	69	33	wyss	wyss	NOUN
brainmatters-1083	69	34	-	-	PUNCT
brainmatters-1083	69	35	coray	coray	NOUN
brainmatters-1083	69	36	,	,	PUNCT
brainmatters-1083	69	37	t.	t.	PROPN
brainmatters-1083	69	38	(	(	PUNCT
brainmatters-1083	69	39	1994	1994	NUM
brainmatters-1083	69	40	)	)	PUNCT
brainmatters-1083	69	41	.	.	PUNCT
brainmatters-1083	70	1	t	t	PROPN
brainmatters-1083	70	2	cells	cell	NOUN
brainmatters-1083	70	3	as	as	ADP
brainmatters-1083	70	4	antigenpresenting	antigenpresente	VERB
brainmatters-1083	70	5	cells	cell	NOUN
brainmatters-1083	70	6	.	.	PUNCT
brainmatters-1083	71	1	immunology	immunology	NOUN
brainmatters-1083	71	2	today	today	NOUN
brainmatters-1083	71	3	,	,	PUNCT
brainmatters-1083	71	4	15(7	15(7	NUM
brainmatters-1083	71	5	)	)	PUNCT
brainmatters-1083	71	6	,	,	PUNCT
brainmatters-1083	71	7	312–315	312–315	NUM
brainmatters-1083	71	8	.	.	PUNCT
brainmatters-1083	72	1	https://doi.org/10.1016/0167-5699(94)90078-7	https://doi.org/10.1016/0167-5699(94)90078-7	NOUN
brainmatters-1083	72	2	10	10	NUM
brainmatters-1083	72	3	.	.	PUNCT
brainmatters-1083	73	1	alcina	alcina	PROPN
brainmatters-1083	73	2	,	,	PUNCT
brainmatters-1083	73	3	a.	a.	PROPN
brainmatters-1083	73	4	,	,	PUNCT
brainmatters-1083	73	5	abad	abad	PROPN
brainmatters-1083	73	6	-	-	PUNCT
brainmatters-1083	73	7	grau	grau	PROPN
brainmatters-1083	73	8	,	,	PUNCT
brainmatters-1083	73	9	m.	m.	NOUN
brainmatters-1083	73	10	,	,	PUNCT
brainmatters-1083	73	11	fedetz	fedetz	NOUN
brainmatters-1083	73	12	,	,	PUNCT
brainmatters-1083	73	13	m.	m.	NOUN
brainmatters-1083	73	14	,	,	PUNCT
brainmatters-1083	73	15	et	et	PROPN
brainmatters-1083	73	16	al	al	PROPN
brainmatters-1083	73	17	.	.	PUNCT
brainmatters-1083	73	18	(	(	PUNCT
brainmatters-1083	73	19	2012	2012	NUM
brainmatters-1083	73	20	)	)	PUNCT
brainmatters-1083	73	21	.	.	PUNCT
brainmatters-1083	74	1	multiple	multiple	ADJ
brainmatters-1083	74	2	sclerosis	sclerosis	NOUN
brainmatters-1083	74	3	risk	risk	NOUN
brainmatters-1083	74	4	variant	variant	PROPN
brainmatters-1083	74	5	hla	hla	PROPN
brainmatters-1083	74	6	-	-	PUNCT
brainmatters-1083	74	7	drb1	drb1	NOUN
brainmatters-1083	74	8	*	*	NUM
brainmatters-1083	74	9	1501	1501	NUM
brainmatters-1083	74	10	associates	associate	NOUN
brainmatters-1083	74	11	with	with	ADP
brainmatters-1083	74	12	high	high	ADJ
brainmatters-1083	74	13	expression	expression	NOUN
brainmatters-1083	74	14	of	of	ADP
brainmatters-1083	74	15	drb1	drb1	ADJ
brainmatters-1083	74	16	gene	gene	NOUN
brainmatters-1083	74	17	in	in	ADP
brainmatters-1083	74	18	different	different	ADJ
brainmatters-1083	74	19	human	human	ADJ
brainmatters-1083	74	20	populations	population	NOUN
brainmatters-1083	74	21	.	.	PUNCT
brainmatters-1083	75	1	plos	plos	PROPN
brainmatters-1083	75	2	one	one	NUM
brainmatters-1083	75	3	,	,	PUNCT
brainmatters-1083	75	4	7(1	7(1	NUM
brainmatters-1083	75	5	)	)	PUNCT
brainmatters-1083	75	6	,	,	PUNCT
brainmatters-1083	75	7	e29819	e29819	PROPN
brainmatters-1083	75	8	.	.	PUNCT
brainmatters-1083	76	1	https://doi.org/10.1371/journal.pone.0029819	https://doi.org/10.1371/journal.pone.0029819	VERB
brainmatters-1083	76	2	11	11	NUM
brainmatters-1083	76	3	.	.	PUNCT
brainmatters-1083	77	1	james	james	PROPN
brainmatters-1083	77	2	,	,	PUNCT
brainmatters-1083	77	3	l.	l.	PROPN
brainmatters-1083	77	4	m.	m.	PROPN
brainmatters-1083	77	5	,	,	PUNCT
brainmatters-1083	77	6	&	&	CCONJ
brainmatters-1083	77	7	georgopoulos	georgopoulo	NOUN
brainmatters-1083	77	8	,	,	PUNCT
brainmatters-1083	77	9	a.	a.	NOUN
brainmatters-1083	77	10	p.	p.	NOUN
brainmatters-1083	77	11	(	(	PUNCT
brainmatters-1083	77	12	2019	2019	NUM
brainmatters-1083	77	13	)	)	PUNCT
brainmatters-1083	77	14	.	.	PUNCT
brainmatters-1083	78	1	dementias	dementia	NOUN
brainmatters-1083	78	2	caused	cause	VERB
brainmatters-1083	78	3	by	by	ADP
brainmatters-1083	78	4	persistent	persistent	ADJ
brainmatters-1083	78	5	pathogens	pathogen	NOUN
brainmatters-1083	78	6	and	and	CCONJ
brainmatters-1083	78	7	the	the	DET
brainmatters-1083	78	8	protective	protective	ADJ
brainmatters-1083	78	9	role	role	NOUN
brainmatters-1083	78	10	of	of	ADP
brainmatters-1083	78	11	hla	hla	NOUN
brainmatters-1083	78	12	against	against	ADP
brainmatters-1083	78	13	them	they	PRON
brainmatters-1083	78	14	.	.	PUNCT
brainmatters-1083	79	1	journal	journal	PROPN
brainmatters-1083	79	2	of	of	ADP
brainmatters-1083	79	3	neurology	neurology	NOUN
brainmatters-1083	79	4	&	&	CCONJ
brainmatters-1083	79	5	neuromedicine	neuromedicine	PROPN
brainmatters-1083	79	6	,	,	PUNCT
brainmatters-1083	79	7	5(1	5(1	NUM
brainmatters-1083	79	8	)	)	PUNCT
brainmatters-1083	79	9	.	.	PUNCT
brainmatters-1083	80	1	https://www.jneurology.com/articles/dementiascaused-by-persistent-pathogens-and-the-protective-roleof-hla-against-them.html	https://www.jneurology.com/articles/dementiascaused-by-persistent-pathogens-and-the-protective-roleof-hla-against-them.html	PROPN
brainmatters-1083	80	2	12	12	NUM
brainmatters-1083	80	3	.	.	PUNCT
brainmatters-1083	81	1	sospedra	sospedra	NOUN
brainmatters-1083	81	2	,	,	PUNCT
brainmatters-1083	81	3	m.	m.	NOUN
brainmatters-1083	81	4	,	,	PUNCT
brainmatters-1083	81	5	&	&	CCONJ
brainmatters-1083	81	6	martin	martin	PROPN
brainmatters-1083	81	7	,	,	PUNCT
brainmatters-1083	81	8	r.	r.	PROPN
brainmatters-1083	81	9	(	(	PUNCT
brainmatters-1083	81	10	2005	2005	NUM
brainmatters-1083	81	11	)	)	PUNCT
brainmatters-1083	81	12	.	.	PUNCT
brainmatters-1083	82	1	immune	immune	ADJ
brainmatters-1083	82	2	reactions	reaction	NOUN
brainmatters-1083	82	3	in	in	ADP
brainmatters-1083	82	4	multiple	multiple	ADJ
brainmatters-1083	82	5	sclerosis	sclerosis	NOUN
brainmatters-1083	82	6	.	.	PUNCT
brainmatters-1083	83	1	the	the	DET
brainmatters-1083	83	2	lancet	lancet	PROPN
brainmatters-1083	83	3	neurology	neurology	NOUN
brainmatters-1083	83	4	,	,	PUNCT
brainmatters-1083	83	5	4(3	4(3	NUM
brainmatters-1083	83	6	)	)	PUNCT
brainmatters-1083	83	7	,	,	PUNCT
brainmatters-1083	83	8	168	168	NUM
brainmatters-1083	83	9	-	-	SYM
brainmatters-1083	83	10	180	180	NUM
brainmatters-1083	83	11	.	.	PUNCT
brainmatters-1083	83	12	https://doi.org/10.1016/s1474-4422(05)70020-5	https://doi.org/10.1016/s1474-4422(05)70020-5	PROPN
brainmatters-1083	83	13	13	13	NUM
brainmatters-1083	83	14	.	.	PUNCT
brainmatters-1083	84	1	tur	tur	PROPN
brainmatters-1083	84	2	,	,	PUNCT
brainmatters-1083	84	3	c.	c.	NOUN
brainmatters-1083	84	4	,	,	PUNCT
brainmatters-1083	84	5	ramagopalan	ramagopalan	NOUN
brainmatters-1083	84	6	,	,	PUNCT
brainmatters-1083	84	7	s.	s.	PROPN
brainmatters-1083	84	8	,	,	PUNCT
brainmatters-1083	84	9	altmann	altmann	PROPN
brainmatters-1083	84	10	,	,	PUNCT
brainmatters-1083	84	11	d.	d.	PROPN
brainmatters-1083	84	12	r.	r.	PROPN
brainmatters-1083	84	13	,	,	PUNCT
brainmatters-1083	84	14	et	et	PROPN
brainmatters-1083	84	15	al	al	PROPN
brainmatters-1083	84	16	.	.	PUNCT
brainmatters-1083	85	1	(	(	PUNCT
brainmatters-1083	85	2	2014	2014	NUM
brainmatters-1083	85	3	)	)	PUNCT
brainmatters-1083	85	4	.	.	PUNCT
brainmatters-1083	86	1	hla	hla	PROPN
brainmatters-1083	86	2	-	-	PUNCT
brainmatters-1083	86	3	drb1	drb1	PROPN
brainmatters-1083	86	4	*	*	NUM
brainmatters-1083	86	5	15	15	NUM
brainmatters-1083	86	6	influences	influence	VERB
brainmatters-1083	86	7	the	the	DET
brainmatters-1083	86	8	development	development	NOUN
brainmatters-1083	86	9	of	of	ADP
brainmatters-1083	86	10	brain	brain	NOUN
brainmatters-1083	86	11	tissue	tissue	NOUN
brainmatters-1083	86	12	damage	damage	NOUN
brainmatters-1083	86	13	in	in	ADP
brainmatters-1083	86	14	early	early	ADJ
brainmatters-1083	86	15	ppms	ppm	NOUN
brainmatters-1083	86	16	.	.	PUNCT
brainmatters-1083	86	17	neurology	neurology	PROPN
brainmatters-1083	86	18	,	,	PUNCT
brainmatters-1083	86	19	83(19	83(19	NUM
brainmatters-1083	86	20	)	)	PUNCT
brainmatters-1083	86	21	,	,	PUNCT
brainmatters-1083	86	22	1712–1718	1712–1718	NUM
brainmatters-1083	86	23	.	.	PUNCT
brainmatters-1083	87	1	https://doi.org/10.1212/wnl.0000000000000959	https://doi.org/10.1212/wnl.0000000000000959	NOUN
brainmatters-1083	87	2	14	14	NUM
brainmatters-1083	87	3	.	.	PUNCT
brainmatters-1083	88	1	hsu	hsu	PROPN
brainmatters-1083	88	2	,	,	PUNCT
brainmatters-1083	88	3	p.	p.	PROPN
brainmatters-1083	88	4	d.	d.	PROPN
brainmatters-1083	88	5	,	,	PUNCT
brainmatters-1083	88	6	lander	lander	PROPN
brainmatters-1083	88	7	,	,	PUNCT
brainmatters-1083	88	8	e.	e.	PROPN
brainmatters-1083	88	9	s.	s.	PROPN
brainmatters-1083	88	10	,	,	PUNCT
brainmatters-1083	88	11	&	&	CCONJ
brainmatters-1083	88	12	zhang	zhang	PROPN
brainmatters-1083	88	13	,	,	PUNCT
brainmatters-1083	88	14	f.	f.	PROPN
brainmatters-1083	88	15	(	(	PUNCT
brainmatters-1083	88	16	2014	2014	NUM
brainmatters-1083	88	17	)	)	PUNCT
brainmatters-1083	88	18	.	.	PUNCT
brainmatters-1083	89	1	targeted	target	VERB
brainmatters-1083	89	2	gene	gene	NOUN
brainmatters-1083	89	3	editing	editing	NOUN
brainmatters-1083	89	4	using	use	VERB
brainmatters-1083	89	5	crispr	crispr	ADJ
brainmatters-1083	89	6	/	/	SYM
brainmatters-1083	89	7	cas9	cas9	NOUN
brainmatters-1083	89	8	:	:	PUNCT
brainmatters-1083	89	9	a	a	DET
brainmatters-1083	89	10	review	review	NOUN
brainmatters-1083	89	11	of	of	ADP
brainmatters-1083	89	12	its	its	PRON
brainmatters-1083	89	13	applications	application	NOUN
brainmatters-1083	89	14	in	in	ADP
brainmatters-1083	89	15	human	human	ADJ
brainmatters-1083	89	16	diseases	disease	NOUN
brainmatters-1083	89	17	.	.	PUNCT
brainmatters-1083	90	1	nature	nature	NOUN
brainmatters-1083	90	2	reviews	review	VERB
brainmatters-1083	90	3	genetics	genetic	NOUN
brainmatters-1083	90	4	,	,	PUNCT
brainmatters-1083	90	5	15(5	15(5	NUM
brainmatters-1083	90	6	)	)	PUNCT
brainmatters-1083	90	7	,	,	PUNCT
brainmatters-1083	90	8	321	321	NUM
brainmatters-1083	90	9	-	-	SYM
brainmatters-1083	90	10	334	334	NUM
brainmatters-1083	90	11	.	.	PUNCT
brainmatters-1083	91	1	https://doi.org/10.1038/nrg.2014.36	https://doi.org/10.1038/nrg.2014.36	NOUN
brainmatters-1083	91	2	15	15	NUM
brainmatters-1083	91	3	.	.	PUNCT
brainmatters-1083	92	1	kiss	kiss	PROPN
brainmatters-1083	92	2	,	,	PUNCT
brainmatters-1083	92	3	m.	m.	NOUN
brainmatters-1083	92	4	&	&	CCONJ
brainmatters-1083	92	5	mcalpine	mcalpine	PROPN
brainmatters-1083	92	6	,	,	PUNCT
brainmatters-1083	92	7	c.s	c.s	PROPN
brainmatters-1083	92	8	.	.	PROPN
brainmatters-1083	92	9	(	(	PUNCT
brainmatters-1083	92	10	2023	2023	NUM
brainmatters-1083	92	11	)	)	PUNCT
brainmatters-1083	92	12	.	.	PUNCT
brainmatters-1083	93	1	a	a	DET
brainmatters-1083	93	2	key	key	ADJ
brainmatters-1083	93	3	biological	biological	ADJ
brainmatters-1083	93	4	pathway	pathway	NOUN
brainmatters-1083	93	5	for	for	ADP
brainmatters-1083	93	6	multiple	multiple	ADJ
brainmatters-1083	93	7	sclerosis	sclerosis	NOUN
brainmatters-1083	93	8	is	be	AUX
brainmatters-1083	93	9	uncovered	uncover	VERB
brainmatters-1083	93	10	by	by	ADP
brainmatters-1083	93	11	mount	mount	PROPN
brainmatters-1083	93	12	sinai	sinai	PROPN
brainmatters-1083	93	13	researchers	researchers	PROPN
brainmatters-1083	93	14	.	.	PUNCT
brainmatters-1083	94	1	mount	mount	PROPN
brainmatters-1083	94	2	sinai	sinai	PROPN
brainmatters-1083	94	3	health	health	PROPN
brainmatters-1083	94	4	system	system	NOUN
brainmatters-1083	94	5	.	.	PUNCT
brainmatters-1083	95	1	references	reference	NOUN
brainmatters-1083	95	2	1	1	NUM
brainmatters-1083	95	3	.	.	X
brainmatters-1083	96	1	harris	harris	PROPN
brainmatters-1083	96	2	,	,	PUNCT
brainmatters-1083	96	3	t.	t.	PROPN
brainmatters-1083	96	4	c.	c.	PROPN
brainmatters-1083	96	5	,	,	PUNCT
brainmatters-1083	96	6	de	de	X
brainmatters-1083	96	7	rooij	rooij	PROPN
brainmatters-1083	96	8	,	,	PUNCT
brainmatters-1083	96	9	r.	r.	PROPN
brainmatters-1083	96	10	,	,	PUNCT
brainmatters-1083	96	11	&	&	CCONJ
brainmatters-1083	96	12	kuhl	kuhl	PROPN
brainmatters-1083	96	13	,	,	PUNCT
brainmatters-1083	96	14	e.	e.	PROPN
brainmatters-1083	96	15	(	(	PUNCT
brainmatters-1083	96	16	2019	2019	NUM
brainmatters-1083	96	17	)	)	PUNCT
brainmatters-1083	96	18	.	.	PUNCT
brainmatters-1083	97	1	the	the	DET
brainmatters-1083	97	2	shrinking	shrink	VERB
brainmatters-1083	97	3	brain	brain	NOUN
brainmatters-1083	97	4	:	:	PUNCT
brainmatters-1083	97	5	cerebral	cerebral	ADJ
brainmatters-1083	97	6	atrophy	atrophy	NOUN
brainmatters-1083	97	7	following	follow	VERB
brainmatters-1083	97	8	traumatic	traumatic	ADJ
brainmatters-1083	97	9	brain	brain	NOUN
brainmatters-1083	97	10	injury	injury	NOUN
brainmatters-1083	97	11	.	.	PUNCT
brainmatters-1083	98	1	annals	annal	NOUN
brainmatters-1083	98	2	of	of	ADP
brainmatters-1083	98	3	biomedical	biomedical	ADJ
brainmatters-1083	98	4	engineering	engineering	NOUN
brainmatters-1083	98	5	,	,	PUNCT
brainmatters-1083	98	6	47(9),1941–1959	47(9),1941–1959	NOUN
brainmatters-1083	98	7	.	.	PUNCT
brainmatters-1083	99	1	https://doi.org/10.1007/s10439-018-02148-2	https://doi.org/10.1007/s10439-018-02148-2	NUM
brainmatters-1083	99	2	2	2	NUM
brainmatters-1083	99	3	.	.	PUNCT
brainmatters-1083	99	4	cruz	cruz	NOUN
brainmatters-1083	99	5	-	-	PUNCT
brainmatters-1083	99	6	tapias	tapias	PROPN
brainmatters-1083	99	7	,	,	PUNCT
brainmatters-1083	99	8	p.	p.	NOUN
brainmatters-1083	99	9	(	(	PUNCT
brainmatters-1083	99	10	2013	2013	NUM
brainmatters-1083	99	11	)	)	PUNCT
brainmatters-1083	99	12	.	.	PUNCT
brainmatters-1083	100	1	major	major	ADJ
brainmatters-1083	100	2	histocompatibility	histocompatibility	NOUN
brainmatters-1083	100	3	complex	complex	NOUN
brainmatters-1083	100	4	:	:	PUNCT
brainmatters-1083	100	5	antigen	antigen	NOUN
brainmatters-1083	100	6	processing	processing	NOUN
brainmatters-1083	100	7	and	and	CCONJ
brainmatters-1083	100	8	presentation	presentation	NOUN
brainmatters-1083	100	9	.	.	PUNCT
brainmatters-1083	101	1	https://www.ncbi.nlm.nih.gov/books/nbk459467/#:~:text=h	https://www.ncbi.nlm.nih.gov/books/nbk459467/#:~:text=h	PROPN
brainmatters-1083	101	2	la%20class%20i%20antigens%20are	la%20class%20i%20antigens%20are	PROPN
brainmatters-1083	101	3	,	,	PUNCT
brainmatters-1083	101	4	endothelial%20cells%2	endothelial%20cells%2	NOUN
brainmatters-1083	101	5	c%20and%20thymic%20epithelial	c%20and%20thymic%20epithelial	PROPN
brainmatters-1083	101	6	3	3	NUM
brainmatters-1083	101	7	.	.	PUNCT
brainmatters-1083	101	8	lorefice	lorefice	PROPN
brainmatters-1083	101	9	l	l	PROPN
brainmatters-1083	101	10	,	,	PUNCT
brainmatters-1083	101	11	fenu	fenu	PROPN
brainmatters-1083	101	12	g	g	NOUN
brainmatters-1083	101	13	,	,	PUNCT
brainmatters-1083	101	14	sardu	sardu	PROPN
brainmatters-1083	101	15	c	c	AUX
brainmatters-1083	101	16	,	,	PUNCT
brainmatters-1083	101	17	et	et	PROPN
brainmatters-1083	101	18	al	al	PROPN
brainmatters-1083	101	19	.	.	PROPN
brainmatters-1083	101	20	(	(	PUNCT
brainmatters-1083	101	21	2019	2019	NUM
brainmatters-1083	101	22	)	)	PUNCT
brainmatters-1083	101	23	.	.	PUNCT
brainmatters-1083	102	1	multiple	multiple	ADJ
brainmatters-1083	102	2	sclerosis	sclerosis	NOUN
brainmatters-1083	102	3	and	and	CCONJ
brainmatters-1083	102	4	hla	hla	PROPN
brainmatters-1083	102	5	genotypes	genotype	NOUN
brainmatters-1083	102	6	:	:	PUNCT
brainmatters-1083	102	7	a	a	DET
brainmatters-1083	102	8	possible	possible	ADJ
brainmatters-1083	102	9	influence	influence	NOUN
brainmatters-1083	102	10	on	on	ADP
brainmatters-1083	102	11	brain	brain	NOUN
brainmatters-1083	102	12	atrophy	atrophy	NOUN
brainmatters-1083	102	13	.	.	PUNCT
brainmatters-1083	103	1	multiple	multiple	ADJ
brainmatters-1083	103	2	sclerosis	sclerosis	NOUN
brainmatters-1083	103	3	journal	journal	NOUN
brainmatters-1083	103	4	,	,	PUNCT
brainmatters-1083	103	5	25(1	25(1	NUM
brainmatters-1083	103	6	)	)	PUNCT
brainmatters-1083	103	7	,	,	PUNCT
brainmatters-1083	103	8	23	23	NUM
brainmatters-1083	103	9	-	-	SYM
brainmatters-1083	103	10	30	30	NUM
brainmatters-1083	103	11	.	.	PUNCT
brainmatters-1083	104	1	https://doi.org/10.1177/1352458517739989	https://doi.org/10.1177/1352458517739989	PROPN
brainmatters-1083	104	2	4	4	X
brainmatters-1083	104	3	.	.	PUNCT
brainmatters-1083	105	1	national	national	PROPN
brainmatters-1083	105	2	institute	institute	PROPN
brainmatters-1083	105	3	of	of	ADP
brainmatters-1083	105	4	neurological	neurological	ADJ
brainmatters-1083	105	5	disorders	disorder	NOUN
brainmatters-1083	105	6	and	and	CCONJ
brainmatters-1083	105	7	stroke	stroke	NOUN
brainmatters-1083	105	8	.	.	PUNCT
brainmatters-1083	106	1	(	(	PUNCT
brainmatters-1083	106	2	2024	2024	NUM
brainmatters-1083	106	3	,	,	PUNCT
brainmatters-1083	106	4	july	july	PROPN
brainmatters-1083	106	5	19	19	NUM
brainmatters-1083	106	6	)	)	PUNCT
brainmatters-1083	106	7	.	.	PUNCT
brainmatters-1083	107	1	multiple	multiple	ADJ
brainmatters-1083	107	2	sclerosis	sclerosis	NOUN
brainmatters-1083	107	3	.	.	PUNCT
brainmatters-1083	108	1	www.ninds.nih.gov	www.ninds.nih.gov	NOUN
brainmatters-1083	108	2	.	.	PUNCT
brainmatters-1083	109	1	https://www.ninds.nih.gov/healthinformation/disorders/multiple-sclerosis	https://www.ninds.nih.gov/healthinformation/disorders/multiple-sclerosis	NOUN
brainmatters-1083	109	2	5	5	NUM
brainmatters-1083	109	3	.	.	PUNCT
brainmatters-1083	109	4	hla	hla	NOUN
brainmatters-1083	109	5	protein	protein	NOUN
brainmatters-1083	109	6	.	.	PUNCT
brainmatters-1083	110	1	(	(	PUNCT
brainmatters-1083	110	2	2024	2024	NUM
brainmatters-1083	110	3	)	)	PUNCT
brainmatters-1083	110	4	.	.	PUNCT
brainmatters-1083	111	1	hlaprotein.com	hlaprotein.com	X
brainmatters-1083	111	2	.	.	PUNCT
brainmatters-1083	112	1	https://www.hlaprotein.com/hladrb11501-drb11501	https://www.hlaprotein.com/hladrb11501-drb11501	VERB
brainmatters-1083	113	1	6	6	NUM
brainmatters-1083	113	2	.	.	PUNCT
brainmatters-1083	113	3	grubic	grubic	ADJ
brainmatters-1083	113	4	,	,	PUNCT
brainmatters-1083	113	5	zorana	zorana	PROPN
brainmatters-1083	113	6	.	.	PUNCT
brainmatters-1083	114	1	(	(	PUNCT
brainmatters-1083	114	2	2017	2017	NUM
brainmatters-1083	114	3	)	)	PUNCT
brainmatters-1083	114	4	.	.	PUNCT
brainmatters-1083	115	1	human	human	ADJ
brainmatters-1083	115	2	leukocyte	leukocyte	NOUN
brainmatters-1083	115	3	antigen	antigen	ADJ
brainmatters-1083	115	4	polymorphism	polymorphism	NOUN
brainmatters-1083	115	5	in	in	ADP
brainmatters-1083	115	6	search	search	NOUN
brainmatters-1083	115	7	for	for	ADP
brainmatters-1083	115	8	a	a	DET
brainmatters-1083	115	9	matched	match	VERB
brainmatters-1083	115	10	unrelated	unrelated	ADJ
brainmatters-1083	115	11	donor	donor	NOUN
brainmatters-1083	115	12	in	in	ADP
brainmatters-1083	115	13	haematopoietic	haematopoietic	ADJ
brainmatters-1083	115	14	stem	stem	NOUN
brainmatters-1083	115	15	cell	cell	NOUN
brainmatters-1083	115	16	transplantation	transplantation	NOUN
brainmatters-1083	115	17	.	.	PUNCT
brainmatters-1083	116	1	4	4	NUM
brainmatters-1083	116	2	-	-	SYM
brainmatters-1083	116	3	12	12	NUM
brainmatters-1083	116	4	.	.	PUNCT
brainmatters-1083	117	1	7	7	X
brainmatters-1083	117	2	.	.	X
brainmatters-1083	117	3	scholz	scholz	NOUN
brainmatters-1083	117	4	,	,	PUNCT
brainmatters-1083	117	5	e.	e.	PROPN
brainmatters-1083	117	6	m	m	PROPN
brainmatters-1083	117	7	,	,	PUNCT
brainmatters-1083	117	8	marcilla	marcilla	NOUN
brainmatters-1083	117	9	,	,	PUNCT
brainmatters-1083	117	10	m	m	PROPN
brainmatters-1083	117	11	,	,	PUNCT
brainmatters-1083	117	12	daura	daura	NOUN
brainmatters-1083	117	13	,	,	PUNCT
brainmatters-1083	117	14	x	x	PRON
brainmatters-1083	117	15	,	,	PUNCT
brainmatters-1083	117	16	et	et	PROPN
brainmatters-1083	117	17	al	al	PROPN
brainmatters-1083	117	18	.	.	PUNCT
brainmatters-1083	117	19	(	(	PUNCT
brainmatters-1083	117	20	2017	2017	NUM
brainmatters-1083	117	21	)	)	PUNCT
brainmatters-1083	117	22	.	.	PUNCT
brainmatters-1083	118	1	human	human	ADJ
brainmatters-1083	118	2	leukocyte	leukocyte	NOUN
brainmatters-1083	118	3	antigen	antigen	NOUN
brainmatters-1083	118	4	(	(	PUNCT
brainmatters-1083	118	5	hla)-drb1	hla)-drb1	NOUN
brainmatters-1083	118	6	*	*	SYM
brainmatters-1083	118	7	15:01	15:01	NUM
brainmatters-1083	118	8	and	and	CCONJ
brainmatters-1083	118	9	hla	hla	NOUN
brainmatters-1083	118	10	-	-	PUNCT
brainmatters-1083	118	11	drb5	drb5	PROPN
brainmatters-1083	118	12	*	*	SYM
brainmatters-1083	118	13	01:01	01:01	NUM
brainmatters-1083	118	14	present	present	ADJ
brainmatters-1083	118	15	complementary	complementary	ADJ
brainmatters-1083	118	16	peptide	peptide	NOUN
brainmatters-1083	118	17	repertoires	repertoire	NOUN
brainmatters-1083	118	18	.	.	PUNCT
brainmatters-1083	119	1	8	8	X
brainmatters-1083	119	2	.	.	PUNCT
brainmatters-1083	119	3	eckersley	eckersley	NOUN
brainmatters-1083	119	4	-	-	PUNCT
brainmatters-1083	119	5	maslin	maslin	PROPN
brainmatters-1083	119	6	,	,	PUNCT
brainmatters-1083	119	7	m.	m.	NOUN
brainmatters-1083	119	8	a.	a.	PROPN
brainmatters-1083	119	9	,	,	PUNCT
brainmatters-1083	119	10	&	&	CCONJ
brainmatters-1083	119	11	spector	spector	PROPN
brainmatters-1083	119	12	,	,	PUNCT
brainmatters-1083	119	13	d.	d.	PROPN
brainmatters-1083	119	14	l.	l.	PROPN
brainmatters-1083	119	15	(	(	PUNCT
brainmatters-1083	119	16	2014	2014	NUM
brainmatters-1083	119	17	)	)	PUNCT
brainmatters-1083	119	18	.	.	PUNCT
brainmatters-1083	120	1	random	random	ADJ
brainmatters-1083	120	2	monoallelic	monoallelic	ADJ
brainmatters-1083	120	3	expression	expression	NOUN
brainmatters-1083	120	4	:	:	PUNCT
brainmatters-1083	120	5	regulating	regulate	VERB
brainmatters-1083	120	6	gene	gene	NOUN
brainmatters-1083	120	7	expression	expression	NOUN
brainmatters-1083	120	8	one	one	NUM
brainmatters-1083	120	9	allele	allele	NOUN
brainmatters-1083	120	10	at	at	ADP
brainmatters-1083	120	11	a	a	DET
brainmatters-1083	120	12	time	time	NOUN
brainmatters-1083	120	13	.	.	PUNCT
brainmatters-1083	121	1	trends	trend	NOUN
brainmatters-1083	121	2	in	in	ADP
brainmatters-1083	121	3	genetics	genetic	NOUN
brainmatters-1083	121	4	,	,	PUNCT
brainmatters-1083	121	5	30(6	30(6	NUM
brainmatters-1083	121	6	)	)	PUNCT
brainmatters-1083	121	7	,	,	PUNCT
brainmatters-1083	121	8	237–244	237–244	NUM
brainmatters-1083	121	9	.	.	PUNCT
brainmatters-1083	122	1	https://doi.org/10.1016/j.tig.2014.03.003	https://doi.org/10.1016/j.tig.2014.03.003	NOUN
brainmatters-1083	122	2	9	9	NUM
brainmatters-1083	122	3	the	the	DET
brainmatters-1083	122	4	role	role	NOUN
brainmatters-1083	122	5	of	of	ADP
brainmatters-1083	122	6	human	human	ADJ
brainmatters-1083	122	7	leukocyte	leukocyte	NOUN
brainmatters-1083	122	8	antigensin	antigensin	NOUN
brainmatters-1083	122	9	multiple	multiple	ADJ
brainmatters-1083	122	10	sclerosis	sclerosis	NOUN
brainmatters-1083	122	11	and	and	CCONJ
brainmatters-1083	122	12	brain	brain	NOUN
brainmatters-1083	122	13	atrophy	atrophy	NOUN
brainmatters-1083	122	14	tanisha	tanisha	PROPN
brainmatters-1083	122	15	mandal	mandal	PROPN
brainmatters-1083	122	16	tanisha	tanisha	PROPN
brainmatters-1083	122	17	mandal	mandal	PROPN
brainmatters-1083	122	18	is	be	AUX
brainmatters-1083	122	19	a	a	DET
brainmatters-1083	122	20	freshman	freshman	NOUN
brainmatters-1083	122	21	at	at	ADP
brainmatters-1083	122	22	the	the	DET
brainmatters-1083	122	23	university	university	PROPN
brainmatters-1083	122	24	of	of	ADP
brainmatters-1083	122	25	illinois	illinois	PROPN
brainmatters-1083	122	26	,	,	PUNCT
brainmatters-1083	122	27	studying	study	VERB
brainmatters-1083	122	28	neural	neural	ADJ
brainmatters-1083	122	29	engineering	engineering	NOUN
brainmatters-1083	122	30	with	with	ADP
brainmatters-1083	122	31	a	a	DET
brainmatters-1083	122	32	minor	minor	ADJ
brainmatters-1083	122	33	in	in	ADP
brainmatters-1083	122	34	computer	computer	NOUN
brainmatters-1083	122	35	science	science	NOUN
brainmatters-1083	122	36	.	.	PUNCT
brainmatters-1083	123	1	her	her	PRON
brainmatters-1083	123	2	interests	interest	NOUN
brainmatters-1083	123	3	in	in	ADP
brainmatters-1083	123	4	neuroscience	neuroscience	NOUN
brainmatters-1083	123	5	include	include	VERB
brainmatters-1083	123	6	computational	computational	ADJ
brainmatters-1083	123	7	neuroscience	neuroscience	NOUN
brainmatters-1083	123	8	,	,	PUNCT
brainmatters-1083	123	9	specifically	specifically	ADV
brainmatters-1083	123	10	its	its	PRON
brainmatters-1083	123	11	applications	application	NOUN
brainmatters-1083	123	12	in	in	ADP
brainmatters-1083	123	13	treating	treat	VERB
brainmatters-1083	123	14	neurodegenerative	neurodegenerative	ADJ
brainmatters-1083	123	15	diseases	disease	NOUN
brainmatters-1083	123	16	,	,	PUNCT
brainmatters-1083	123	17	and	and	CCONJ
brainmatters-1083	123	18	internal	internal	ADJ
brainmatters-1083	123	19	causes	cause	NOUN
brainmatters-1083	123	20	of	of	ADP
brainmatters-1083	123	21	severe	severe	ADJ
brainmatters-1083	123	22	brain	brain	NOUN
brainmatters-1083	123	23	lesions	lesion	NOUN
brainmatters-1083	123	24	,	,	PUNCT
brainmatters-1083	123	25	such	such	ADJ
brainmatters-1083	123	26	as	as	ADP
brainmatters-1083	123	27	brain	brain	NOUN
brainmatters-1083	123	28	cancer	cancer	NOUN
brainmatters-1083	123	29	.	.	PUNCT
brainmatters-1083	124	1	she	she	PRON
brainmatters-1083	124	2	also	also	ADV
brainmatters-1083	124	3	enjoys	enjoy	VERB
brainmatters-1083	124	4	going	go	VERB
brainmatters-1083	124	5	skiing	ski	VERB
brainmatters-1083	124	6	,	,	PUNCT
brainmatters-1083	124	7	playing	play	VERB
brainmatters-1083	124	8	cards	card	NOUN
brainmatters-1083	124	9	,	,	PUNCT
brainmatters-1083	124	10	and	and	CCONJ
brainmatters-1083	124	11	listening	listen	VERB
brainmatters-1083	124	12	to	to	ADP
brainmatters-1083	124	13	music	music	NOUN
brainmatters-1083	124	14	.	.	PUNCT
brainmatters-1083	125	1	tanisha	tanisha	PROPN
brainmatters-1083	125	2	was	be	AUX
brainmatters-1083	125	3	interested	interested	ADJ
brainmatters-1083	125	4	in	in	ADP
brainmatters-1083	125	5	being	be	AUX
brainmatters-1083	125	6	a	a	DET
brainmatters-1083	125	7	writer	writer	NOUN
brainmatters-1083	125	8	for	for	ADP
brainmatters-1083	125	9	brain	brain	NOUN
brainmatters-1083	125	10	matters	matter	NOUN
brainmatters-1083	125	11	to	to	PART
brainmatters-1083	125	12	have	have	VERB
brainmatters-1083	125	13	the	the	DET
brainmatters-1083	125	14	opportunity	opportunity	NOUN
brainmatters-1083	125	15	to	to	PART
brainmatters-1083	125	16	practice	practice	VERB
brainmatters-1083	125	17	writing	write	VERB
brainmatters-1083	125	18	her	her	PRON
brainmatters-1083	125	19	own	own	ADJ
brainmatters-1083	125	20	research	research	NOUN
brainmatters-1083	125	21	papers	paper	NOUN
brainmatters-1083	125	22	in	in	ADP
brainmatters-1083	125	23	the	the	DET
brainmatters-1083	125	24	future	future	NOUN
brainmatters-1083	125	25	and	and	CCONJ
brainmatters-1083	125	26	explore	explore	VERB
brainmatters-1083	125	27	new	new	ADJ
brainmatters-1083	125	28	neuroscience	neuroscience	NOUN
brainmatters-1083	125	29	topics	topic	NOUN
brainmatters-1083	125	30	in	in	ADP
brainmatters-1083	125	31	depth	depth	NOUN
brainmatters-1083	125	32	.	.	PUNCT
brainmatters-1083	126	1	outside	outside	ADP
brainmatters-1083	126	2	of	of	ADP
brainmatters-1083	126	3	brain	brain	NOUN
brainmatters-1083	126	4	matters	matter	NOUN
brainmatters-1083	126	5	,	,	PUNCT
brainmatters-1083	126	6	tanisha	tanisha	PROPN
brainmatters-1083	126	7	is	be	AUX
brainmatters-1083	126	8	involved	involve	VERB
brainmatters-1083	126	9	in	in	ADP
brainmatters-1083	126	10	research	research	NOUN
brainmatters-1083	126	11	programs	program	NOUN
brainmatters-1083	126	12	such	such	ADJ
brainmatters-1083	126	13	as	as	ADP
brainmatters-1083	126	14	neurotech	neurotech	NOUN
brainmatters-1083	126	15	’s	’s	PART
brainmatters-1083	126	16	cortex	cortex	NOUN
brainmatters-1083	126	17	codex	codex	NOUN
brainmatters-1083	126	18	and	and	CCONJ
brainmatters-1083	126	19	ur2phd	ur2phd	NOUN
brainmatters-1083	126	20	,	,	PUNCT
brainmatters-1083	126	21	and	and	CCONJ
brainmatters-1083	126	22	fun	fun	VERB
brainmatters-1083	126	23	rsos	rsos	ADP
brainmatters-1083	126	24	such	such	ADJ
brainmatters-1083	126	25	as	as	ADP
brainmatters-1083	126	26	the	the	DET
brainmatters-1083	126	27	cooking	cooking	NOUN
brainmatters-1083	126	28	collective	collective	NOUN
brainmatters-1083	126	29	and	and	CCONJ
brainmatters-1083	126	30	uiuc	uiuc	PROPN
brainmatters-1083	126	31	’s	’s	PART
brainmatters-1083	126	32	book	book	NOUN
brainmatters-1083	126	33	club	club	NOUN
brainmatters-1083	126	34	!	!	PUNCT
brainmatters-1083	127	1	10	10	NUM