id	sid	tid	token	lemma	pos
brainmatters-1084	1	1	brain	brain	NOUN
brainmatters-1084	1	2	matters	matter	NOUN
brainmatters-1084	1	3	vol	vol	NOUN
brainmatters-1084	1	4	.	.	PROPN
brainmatters-1084	1	5	8	8	NUM
brainmatters-1084	2	1	no	no	NOUN
brainmatters-1084	2	2	.	.	NOUN
brainmatters-1084	2	3	2	2	NUM
brainmatters-1084	3	1	the	the	DET
brainmatters-1084	3	2	critical	critical	ADJ
brainmatters-1084	3	3	window	window	NOUN
brainmatters-1084	3	4	for	for	ADP
brainmatters-1084	3	5	estrogen	estrogen	NOUN
brainmatters-1084	3	6	replacement	replacement	NOUN
brainmatters-1084	3	7	therapy	therapy	NOUN
brainmatters-1084	3	8	in	in	ADP
brainmatters-1084	3	9	menopausal	menopausal	ADJ
brainmatters-1084	3	10	women	woman	NOUN
brainmatters-1084	3	11	:	:	PUNCT
brainmatters-1084	3	12	exploring	explore	VERB
brainmatters-1084	3	13	the	the	DET
brainmatters-1084	3	14	neuroprotective	neuroprotective	ADJ
brainmatters-1084	3	15	effects	effect	NOUN
brainmatters-1084	3	16	of	of	ADP
brainmatters-1084	3	17	estrogen	estrogen	NOUN
brainmatters-1084	3	18	in	in	ADP
brainmatters-1084	3	19	reducing	reduce	VERB
brainmatters-1084	3	20	dementia	dementia	NOUN
brainmatters-1084	3	21	risk	risk	NOUN
brainmatters-1084	3	22	menopause	menopause	NOUN
brainmatters-1084	3	23	,	,	PUNCT
brainmatters-1084	3	24	characterized	characterize	VERB
brainmatters-1084	3	25	by	by	ADP
brainmatters-1084	3	26	a	a	DET
brainmatters-1084	3	27	significant	significant	ADJ
brainmatters-1084	3	28	decline	decline	NOUN
brainmatters-1084	3	29	in	in	ADP
brainmatters-1084	3	30	estrogen	estrogen	NOUN
brainmatters-1084	3	31	levels	level	NOUN
brainmatters-1084	3	32	,	,	PUNCT
brainmatters-1084	3	33	profoundly	profoundly	ADV
brainmatters-1084	3	34	impacts	impact	VERB
brainmatters-1084	3	35	brain	brain	NOUN
brainmatters-1084	3	36	health	health	NOUN
brainmatters-1084	3	37	,	,	PUNCT
brainmatters-1084	3	38	influencing	influence	VERB
brainmatters-1084	3	39	cognitive	cognitive	ADJ
brainmatters-1084	3	40	functions	function	NOUN
brainmatters-1084	3	41	and	and	CCONJ
brainmatters-1084	3	42	neurobiological	neurobiological	ADJ
brainmatters-1084	3	43	integrity	integrity	NOUN
brainmatters-1084	3	44	.	.	PUNCT
brainmatters-1084	4	1	estrogen	estrogen	NOUN
brainmatters-1084	4	2	replacement	replacement	NOUN
brainmatters-1084	4	3	therapy	therapy	NOUN
brainmatters-1084	4	4	(	(	PUNCT
brainmatters-1084	4	5	ert	ert	PROPN
brainmatters-1084	4	6	)	)	PUNCT
brainmatters-1084	4	7	,	,	PUNCT
brainmatters-1084	4	8	especially	especially	ADV
brainmatters-1084	4	9	when	when	SCONJ
brainmatters-1084	4	10	administered	administer	VERB
brainmatters-1084	4	11	within	within	ADP
brainmatters-1084	4	12	a	a	DET
brainmatters-1084	4	13	"	"	PUNCT
brainmatters-1084	4	14	critical	critical	ADJ
brainmatters-1084	4	15	window	window	NOUN
brainmatters-1084	4	16	"	"	PUNCT
brainmatters-1084	4	17	near	near	ADP
brainmatters-1084	4	18	the	the	DET
brainmatters-1084	4	19	onset	onset	NOUN
brainmatters-1084	4	20	of	of	ADP
brainmatters-1084	4	21	menopause	menopause	NOUN
brainmatters-1084	4	22	,	,	PUNCT
brainmatters-1084	4	23	has	have	AUX
brainmatters-1084	4	24	shown	show	VERB
brainmatters-1084	4	25	promise	promise	NOUN
brainmatters-1084	4	26	in	in	ADP
brainmatters-1084	4	27	mitigating	mitigate	VERB
brainmatters-1084	4	28	cognitive	cognitive	ADJ
brainmatters-1084	4	29	decline	decline	NOUN
brainmatters-1084	4	30	and	and	CCONJ
brainmatters-1084	4	31	reducing	reduce	VERB
brainmatters-1084	4	32	dementia	dementia	NOUN
brainmatters-1084	4	33	risk	risk	NOUN
brainmatters-1084	4	34	.	.	PUNCT
brainmatters-1084	5	1	this	this	DET
brainmatters-1084	5	2	paper	paper	NOUN
brainmatters-1084	5	3	explores	explore	VERB
brainmatters-1084	5	4	the	the	DET
brainmatters-1084	5	5	neurobiological	neurobiological	ADJ
brainmatters-1084	5	6	mechanisms	mechanism	NOUN
brainmatters-1084	5	7	underlying	underlie	VERB
brainmatters-1084	5	8	estrogen	estrogen	NOUN
brainmatters-1084	5	9	’s	’s	PART
brainmatters-1084	5	10	protective	protective	ADJ
brainmatters-1084	5	11	role	role	NOUN
brainmatters-1084	5	12	,	,	PUNCT
brainmatters-1084	5	13	including	include	VERB
brainmatters-1084	5	14	its	its	PRON
brainmatters-1084	5	15	effects	effect	NOUN
brainmatters-1084	5	16	on	on	ADP
brainmatters-1084	5	17	mitochondrial	mitochondrial	ADJ
brainmatters-1084	5	18	health	health	NOUN
brainmatters-1084	5	19	,	,	PUNCT
brainmatters-1084	5	20	synaptic	synaptic	ADJ
brainmatters-1084	5	21	plasticity	plasticity	NOUN
brainmatters-1084	5	22	,	,	PUNCT
brainmatters-1084	5	23	neurogenesis	neurogenesis	NOUN
brainmatters-1084	5	24	,	,	PUNCT
brainmatters-1084	5	25	and	and	CCONJ
brainmatters-1084	5	26	amyloid	amyloid	NOUN
brainmatters-1084	5	27	-	-	PUNCT
brainmatters-1084	5	28	beta	beta	ADJ
brainmatters-1084	5	29	plaque	plaque	NOUN
brainmatters-1084	5	30	clearance	clearance	NOUN
brainmatters-1084	5	31	.	.	PUNCT
brainmatters-1084	6	1	by	by	ADP
brainmatters-1084	6	2	synthesizing	synthesize	VERB
brainmatters-1084	6	3	current	current	ADJ
brainmatters-1084	6	4	literature	literature	NOUN
brainmatters-1084	6	5	,	,	PUNCT
brainmatters-1084	6	6	we	we	PRON
brainmatters-1084	6	7	underscore	underscore	VERB
brainmatters-1084	6	8	the	the	DET
brainmatters-1084	6	9	importance	importance	NOUN
brainmatters-1084	6	10	of	of	ADP
brainmatters-1084	6	11	early	early	ADJ
brainmatters-1084	6	12	ert	ert	NOUN
brainmatters-1084	6	13	initiation	initiation	NOUN
brainmatters-1084	6	14	and	and	CCONJ
brainmatters-1084	6	15	highlight	highlight	VERB
brainmatters-1084	6	16	the	the	DET
brainmatters-1084	6	17	implications	implication	NOUN
brainmatters-1084	6	18	of	of	ADP
brainmatters-1084	6	19	the	the	DET
brainmatters-1084	6	20	critical	critical	ADJ
brainmatters-1084	6	21	window	window	NOUN
brainmatters-1084	6	22	hypothesis	hypothesis	NOUN
brainmatters-1084	6	23	for	for	ADP
brainmatters-1084	6	24	optimizing	optimize	VERB
brainmatters-1084	6	25	cognitive	cognitive	ADJ
brainmatters-1084	6	26	outcomes	outcome	NOUN
brainmatters-1084	6	27	in	in	ADP
brainmatters-1084	6	28	aging	age	VERB
brainmatters-1084	6	29	women	woman	NOUN
brainmatters-1084	6	30	.	.	PUNCT
brainmatters-1084	7	1	written	write	VERB
brainmatters-1084	7	2	by	by	ADP
brainmatters-1084	7	3	sylvia	sylvia	PROPN
brainmatters-1084	7	4	merz	merz	PROPN
brainmatters-1084	7	5	abstract	abstract	PROPN
brainmatters-1084	7	6	introduction	introduction	NOUN
brainmatters-1084	7	7	the	the	DET
brainmatters-1084	7	8	onset	onset	NOUN
brainmatters-1084	7	9	of	of	ADP
brainmatters-1084	7	10	menopause	menopause	NOUN
brainmatters-1084	7	11	is	be	AUX
brainmatters-1084	7	12	marked	mark	VERB
brainmatters-1084	7	13	by	by	ADP
brainmatters-1084	7	14	a	a	DET
brainmatters-1084	7	15	rapid	rapid	ADJ
brainmatters-1084	7	16	decline	decline	NOUN
brainmatters-1084	7	17	in	in	ADP
brainmatters-1084	7	18	circulating	circulate	VERB
brainmatters-1084	7	19	estrogen	estrogen	NOUN
brainmatters-1084	7	20	levels	level	NOUN
brainmatters-1084	7	21	,	,	PUNCT
brainmatters-1084	7	22	which	which	PRON
brainmatters-1084	7	23	significantly	significantly	ADV
brainmatters-1084	7	24	impacts	impact	VERB
brainmatters-1084	7	25	cognitive	cognitive	ADJ
brainmatters-1084	7	26	functioning	functioning	NOUN
brainmatters-1084	7	27	and	and	CCONJ
brainmatters-1084	7	28	neurobiological	neurobiological	ADJ
brainmatters-1084	7	29	integrity	integrity	NOUN
brainmatters-1084	7	30	.	.	PUNCT
brainmatters-1084	8	1	estrogen	estrogen	NOUN
brainmatters-1084	8	2	plays	play	VERB
brainmatters-1084	8	3	a	a	DET
brainmatters-1084	8	4	crucial	crucial	ADJ
brainmatters-1084	8	5	role	role	NOUN
brainmatters-1084	8	6	in	in	ADP
brainmatters-1084	8	7	maintaining	maintain	VERB
brainmatters-1084	8	8	synaptic	synaptic	ADJ
brainmatters-1084	8	9	density	density	NOUN
brainmatters-1084	8	10	,	,	PUNCT
brainmatters-1084	8	11	promoting	promote	VERB
brainmatters-1084	8	12	neurogenesis	neurogenesis	NOUN
brainmatters-1084	8	13	,	,	PUNCT
brainmatters-1084	8	14	and	and	CCONJ
brainmatters-1084	8	15	enhancing	enhance	VERB
brainmatters-1084	8	16	cellular	cellular	ADJ
brainmatters-1084	8	17	resilience	resilience	NOUN
brainmatters-1084	8	18	against	against	ADP
brainmatters-1084	8	19	age	age	NOUN
brainmatters-1084	8	20	-	-	PUNCT
brainmatters-1084	8	21	related	relate	VERB
brainmatters-1084	8	22	stressors	stressor	NOUN
brainmatters-1084	8	23	,	,	PUNCT
brainmatters-1084	8	24	particularly	particularly	ADV
brainmatters-1084	8	25	in	in	ADP
brainmatters-1084	8	26	brain	brain	NOUN
brainmatters-1084	8	27	regions	region	NOUN
brainmatters-1084	8	28	critical	critical	ADJ
brainmatters-1084	8	29	for	for	ADP
brainmatters-1084	8	30	memory	memory	NOUN
brainmatters-1084	8	31	and	and	CCONJ
brainmatters-1084	8	32	executive	executive	ADJ
brainmatters-1084	8	33	function	function	NOUN
brainmatters-1084	8	34	(	(	PUNCT
brainmatters-1084	8	35	sherwin	sherwin	PROPN
brainmatters-1084	8	36	,	,	PUNCT
brainmatters-1084	8	37	2012	2012	NUM
brainmatters-1084	8	38	;	;	PUNCT
brainmatters-1084	8	39	brinton	brinton	PROPN
brainmatters-1084	8	40	,	,	PUNCT
brainmatters-1084	8	41	2013	2013	NUM
brainmatters-1084	8	42	)	)	PUNCT
brainmatters-1084	8	43	.	.	PUNCT
brainmatters-1084	9	1	the	the	DET
brainmatters-1084	9	2	reduction	reduction	NOUN
brainmatters-1084	9	3	in	in	ADP
brainmatters-1084	9	4	estrogen	estrogen	NOUN
brainmatters-1084	9	5	levels	level	NOUN
brainmatters-1084	9	6	during	during	ADP
brainmatters-1084	9	7	menopause	menopause	NOUN
brainmatters-1084	9	8	is	be	AUX
brainmatters-1084	9	9	associated	associate	VERB
brainmatters-1084	9	10	with	with	ADP
brainmatters-1084	9	11	accelerated	accelerate	VERB
brainmatters-1084	9	12	neurodegenerative	neurodegenerative	ADJ
brainmatters-1084	9	13	processes	process	NOUN
brainmatters-1084	9	14	,	,	PUNCT
brainmatters-1084	9	15	contributing	contribute	VERB
brainmatters-1084	9	16	to	to	ADP
brainmatters-1084	9	17	an	an	DET
brainmatters-1084	9	18	increased	increase	VERB
brainmatters-1084	9	19	risk	risk	NOUN
brainmatters-1084	9	20	of	of	ADP
brainmatters-1084	9	21	dementia	dementia	NOUN
brainmatters-1084	9	22	in	in	ADP
brainmatters-1084	9	23	postmenopausal	postmenopausal	ADJ
brainmatters-1084	9	24	women	woman	NOUN
brainmatters-1084	9	25	(	(	PUNCT
brainmatters-1084	9	26	mosconi	mosconi	PROPN
brainmatters-1084	9	27	et	et	PROPN
brainmatters-1084	9	28	al	al	PROPN
brainmatters-1084	9	29	.	.	PROPN
brainmatters-1084	9	30	,	,	PUNCT
brainmatters-1084	9	31	2017	2017	NUM
brainmatters-1084	9	32	;	;	PUNCT
brainmatters-1084	9	33	maki	maki	PROPN
brainmatters-1084	9	34	&	&	CCONJ
brainmatters-1084	9	35	henderson	henderson	PROPN
brainmatters-1084	9	36	,	,	PUNCT
brainmatters-1084	9	37	2020	2020	NUM
brainmatters-1084	9	38	)	)	PUNCT
brainmatters-1084	9	39	.	.	PUNCT
brainmatters-1084	10	1	emerging	emerge	VERB
brainmatters-1084	10	2	evidence	evidence	NOUN
brainmatters-1084	10	3	supports	support	VERB
brainmatters-1084	10	4	the	the	DET
brainmatters-1084	10	5	notion	notion	NOUN
brainmatters-1084	10	6	that	that	SCONJ
brainmatters-1084	10	7	ert	ert	PROPN
brainmatters-1084	10	8	can	can	AUX
brainmatters-1084	10	9	offset	offset	VERB
brainmatters-1084	10	10	cognitive	cognitive	ADJ
brainmatters-1084	10	11	decline	decline	NOUN
brainmatters-1084	10	12	;	;	PUNCT
brainmatters-1084	10	13	however	however	ADV
brainmatters-1084	10	14	,	,	PUNCT
brainmatters-1084	10	15	the	the	DET
brainmatters-1084	10	16	timing	timing	NOUN
brainmatters-1084	10	17	of	of	ADP
brainmatters-1084	10	18	ert	ert	NOUN
brainmatters-1084	10	19	initiation	initiation	NOUN
brainmatters-1084	10	20	is	be	AUX
brainmatters-1084	10	21	critical	critical	ADJ
brainmatters-1084	10	22	.	.	PUNCT
brainmatters-1084	11	1	the	the	DET
brainmatters-1084	11	2	"	"	PUNCT
brainmatters-1084	11	3	critical	critical	ADJ
brainmatters-1084	11	4	window	window	NOUN
brainmatters-1084	11	5	hypothesis	hypothesis	NOUN
brainmatters-1084	11	6	"	"	PUNCT
brainmatters-1084	11	7	posits	posit	NOUN
brainmatters-1084	11	8	that	that	SCONJ
brainmatters-1084	11	9	starting	starting	AUX
brainmatters-1084	11	10	ert	ert	NOUN
brainmatters-1084	11	11	during	during	ADP
brainmatters-1084	11	12	the	the	DET
brainmatters-1084	11	13	menopausal	menopausal	ADJ
brainmatters-1084	11	14	transition	transition	NOUN
brainmatters-1084	11	15	or	or	CCONJ
brainmatters-1084	11	16	shortly	shortly	ADV
brainmatters-1084	11	17	thereafter	thereafter	ADV
brainmatters-1084	11	18	enhances	enhance	VERB
brainmatters-1084	11	19	its	its	PRON
brainmatters-1084	11	20	neuroprotective	neuroprotective	ADJ
brainmatters-1084	11	21	effects	effect	NOUN
brainmatters-1084	11	22	,	,	PUNCT
brainmatters-1084	11	23	while	while	SCONJ
brainmatters-1084	11	24	delayed	delay	VERB
brainmatters-1084	11	25	initiation	initiation	NOUN
brainmatters-1084	11	26	may	may	AUX
brainmatters-1084	11	27	diminish	diminish	VERB
brainmatters-1084	11	28	its	its	PRON
brainmatters-1084	11	29	efficacy	efficacy	NOUN
brainmatters-1084	11	30	or	or	CCONJ
brainmatters-1084	11	31	pose	pose	VERB
brainmatters-1084	11	32	risks	risk	NOUN
brainmatters-1084	11	33	(	(	PUNCT
brainmatters-1084	11	34	whitmer	whitmer	PROPN
brainmatters-1084	11	35	et	et	PROPN
brainmatters-1084	11	36	al	al	PROPN
brainmatters-1084	11	37	.	.	PROPN
brainmatters-1084	11	38	,	,	PUNCT
brainmatters-1084	11	39	2011	2011	NUM
brainmatters-1084	11	40	;	;	PUNCT
brainmatters-1084	11	41	turek	turek	PROPN
brainmatters-1084	11	42	&	&	CCONJ
brainmatters-1084	11	43	gąsior	gąsior	PROPN
brainmatters-1084	11	44	,	,	PUNCT
brainmatters-1084	11	45	2023	2023	NUM
brainmatters-1084	11	46	)	)	PUNCT
brainmatters-1084	11	47	.	.	PUNCT
brainmatters-1084	12	1	this	this	DET
brainmatters-1084	12	2	paper	paper	NOUN
brainmatters-1084	12	3	reviews	review	VERB
brainmatters-1084	12	4	specific	specific	ADJ
brainmatters-1084	12	5	neurobiological	neurobiological	ADJ
brainmatters-1084	12	6	mechanisms	mechanism	NOUN
brainmatters-1084	12	7	through	through	ADP
brainmatters-1084	12	8	which	which	PRON
brainmatters-1084	12	9	estrogen	estrogen	NOUN
brainmatters-1084	12	10	influences	influence	VERB
brainmatters-1084	12	11	brain	brain	NOUN
brainmatters-1084	12	12	health	health	NOUN
brainmatters-1084	12	13	and	and	CCONJ
brainmatters-1084	12	14	examines	examine	VERB
brainmatters-1084	12	15	how	how	SCONJ
brainmatters-1084	12	16	the	the	DET
brainmatters-1084	12	17	timing	timing	NOUN
brainmatters-1084	12	18	of	of	ADP
brainmatters-1084	12	19	ert	ert	NOUN
brainmatters-1084	12	20	initiation	initiation	NOUN
brainmatters-1084	12	21	aligns	align	VERB
brainmatters-1084	12	22	with	with	ADP
brainmatters-1084	12	23	these	these	DET
brainmatters-1084	12	24	mechanisms	mechanism	NOUN
brainmatters-1084	12	25	to	to	PART
brainmatters-1084	12	26	optimize	optimize	VERB
brainmatters-1084	12	27	cognitive	cognitive	ADJ
brainmatters-1084	12	28	outcomes	outcome	NOUN
brainmatters-1084	12	29	.	.	PUNCT
brainmatters-1084	13	1	estrogen	estrogen	PROPN
brainmatters-1084	13	2	's	's	PART
brainmatters-1084	13	3	role	role	NOUN
brainmatters-1084	13	4	in	in	ADP
brainmatters-1084	13	5	key	key	ADJ
brainmatters-1084	13	6	brain	brain	NOUN
brainmatters-1084	13	7	regions	region	NOUN
brainmatters-1084	13	8	estrogen	estrogen	NOUN
brainmatters-1084	13	9	exerts	exert	VERB
brainmatters-1084	13	10	its	its	PRON
brainmatters-1084	13	11	neuroprotective	neuroprotective	ADJ
brainmatters-1084	13	12	effects	effect	NOUN
brainmatters-1084	13	13	primarily	primarily	ADV
brainmatters-1084	13	14	in	in	ADP
brainmatters-1084	13	15	the	the	DET
brainmatters-1084	13	16	hippocampus	hippocampus	NOUN
brainmatters-1084	13	17	and	and	CCONJ
brainmatters-1084	13	18	prefrontal	prefrontal	ADJ
brainmatters-1084	13	19	cortex	cortex	NOUN
brainmatters-1084	13	20	,	,	PUNCT
brainmatters-1084	13	21	regions	region	NOUN
brainmatters-1084	13	22	essential	essential	ADJ
brainmatters-1084	13	23	for	for	ADP
brainmatters-1084	13	24	memory	memory	NOUN
brainmatters-1084	13	25	,	,	PUNCT
brainmatters-1084	13	26	learning	learning	NOUN
brainmatters-1084	13	27	,	,	PUNCT
brainmatters-1084	13	28	and	and	CCONJ
brainmatters-1084	13	29	executive	executive	ADJ
brainmatters-1084	13	30	function	function	NOUN
brainmatters-1084	13	31	.	.	PUNCT
brainmatters-1084	14	1	11	11	NUM
brainmatters-1084	14	2	the	the	DET
brainmatters-1084	14	3	hippocampus	hippocampus	NOUN
brainmatters-1084	14	4	the	the	DET
brainmatters-1084	14	5	hippocampus	hippocampus	NOUN
brainmatters-1084	14	6	is	be	AUX
brainmatters-1084	14	7	critical	critical	ADJ
brainmatters-1084	14	8	for	for	ADP
brainmatters-1084	14	9	neurogenesis	neurogenesis	NOUN
brainmatters-1084	14	10	and	and	CCONJ
brainmatters-1084	14	11	memory	memory	NOUN
brainmatters-1084	14	12	formation	formation	NOUN
brainmatters-1084	14	13	.	.	PUNCT
brainmatters-1084	15	1	estrogen	estrogen	NOUN
brainmatters-1084	15	2	promotes	promote	VERB
brainmatters-1084	15	3	synaptic	synaptic	ADJ
brainmatters-1084	15	4	plasticity	plasticity	NOUN
brainmatters-1084	15	5	and	and	CCONJ
brainmatters-1084	15	6	enhances	enhance	VERB
brainmatters-1084	15	7	long	long	ADJ
brainmatters-1084	15	8	-	-	PUNCT
brainmatters-1084	15	9	term	term	NOUN
brainmatters-1084	15	10	potentiation	potentiation	NOUN
brainmatters-1084	15	11	(	(	PUNCT
brainmatters-1084	15	12	ltp	ltp	NOUN
brainmatters-1084	15	13	)	)	PUNCT
brainmatters-1084	15	14	,	,	PUNCT
brainmatters-1084	15	15	vital	vital	ADJ
brainmatters-1084	15	16	for	for	ADP
brainmatters-1084	15	17	memory	memory	NOUN
brainmatters-1084	15	18	retention	retention	NOUN
brainmatters-1084	15	19	and	and	CCONJ
brainmatters-1084	15	20	cognitive	cognitive	ADJ
brainmatters-1084	15	21	flexibility	flexibility	NOUN
brainmatters-1084	15	22	(	(	PUNCT
brainmatters-1084	15	23	maki	maki	PROPN
brainmatters-1084	15	24	&	&	CCONJ
brainmatters-1084	15	25	henderson	henderson	PROPN
brainmatters-1084	15	26	,	,	PUNCT
brainmatters-1084	15	27	2020	2020	NUM
brainmatters-1084	15	28	)	)	PUNCT
brainmatters-1084	15	29	.	.	PUNCT
brainmatters-1084	16	1	research	research	NOUN
brainmatters-1084	16	2	indicates	indicate	VERB
brainmatters-1084	16	3	that	that	SCONJ
brainmatters-1084	16	4	estrogen	estrogen	NOUN
brainmatters-1084	16	5	supports	support	VERB
brainmatters-1084	16	6	the	the	DET
brainmatters-1084	16	7	maintenance	maintenance	NOUN
brainmatters-1084	16	8	of	of	ADP
brainmatters-1084	16	9	hippocampal	hippocampal	ADJ
brainmatters-1084	16	10	volume	volume	NOUN
brainmatters-1084	16	11	by	by	ADP
brainmatters-1084	16	12	preventing	prevent	VERB
brainmatters-1084	16	13	agerelated	agerelate	VERB
brainmatters-1084	16	14	atrophy	atrophy	NOUN
brainmatters-1084	16	15	and	and	CCONJ
brainmatters-1084	16	16	promoting	promote	VERB
brainmatters-1084	16	17	synaptic	synaptic	ADJ
brainmatters-1084	16	18	connections	connection	NOUN
brainmatters-1084	16	19	(	(	PUNCT
brainmatters-1084	16	20	mosconi	mosconi	PROPN
brainmatters-1084	16	21	et	et	PROPN
brainmatters-1084	16	22	al	al	PROPN
brainmatters-1084	16	23	.	.	PROPN
brainmatters-1084	16	24	,	,	PUNCT
brainmatters-1084	16	25	2017	2017	NUM
brainmatters-1084	16	26	;	;	PUNCT
brainmatters-1084	16	27	liu	liu	PROPN
brainmatters-1084	16	28	et	et	PROPN
brainmatters-1084	16	29	al	al	PROPN
brainmatters-1084	16	30	.	.	PROPN
brainmatters-1084	16	31	,	,	PUNCT
brainmatters-1084	16	32	2019	2019	NUM
brainmatters-1084	16	33	)	)	PUNCT
brainmatters-1084	16	34	.	.	PUNCT
brainmatters-1084	17	1	moreover	moreover	ADV
brainmatters-1084	17	2	,	,	PUNCT
brainmatters-1084	17	3	estrogen	estrogen	NOUN
brainmatters-1084	17	4	enhances	enhance	VERB
brainmatters-1084	17	5	the	the	DET
brainmatters-1084	17	6	expression	expression	NOUN
brainmatters-1084	17	7	of	of	ADP
brainmatters-1084	17	8	synaptic	synaptic	ADJ
brainmatters-1084	17	9	proteins	protein	NOUN
brainmatters-1084	17	10	such	such	ADJ
brainmatters-1084	17	11	as	as	ADP
brainmatters-1084	17	12	synapsin	synapsin	NOUN
brainmatters-1084	17	13	and	and	CCONJ
brainmatters-1084	17	14	psd-95	psd-95	NUM
brainmatters-1084	17	15	,	,	PUNCT
brainmatters-1084	17	16	which	which	PRON
brainmatters-1084	17	17	are	be	AUX
brainmatters-1084	17	18	crucial	crucial	ADJ
brainmatters-1084	17	19	for	for	ADP
brainmatters-1084	17	20	synaptic	synaptic	ADJ
brainmatters-1084	17	21	stability	stability	NOUN
brainmatters-1084	17	22	and	and	CCONJ
brainmatters-1084	17	23	plasticity	plasticity	NOUN
brainmatters-1084	17	24	(	(	PUNCT
brainmatters-1084	17	25	zhou	zhou	PROPN
brainmatters-1084	17	26	et	et	PROPN
brainmatters-1084	17	27	al	al	PROPN
brainmatters-1084	17	28	.	.	PROPN
brainmatters-1084	17	29	,	,	PUNCT
brainmatters-1084	17	30	2017	2017	NUM
brainmatters-1084	17	31	)	)	PUNCT
brainmatters-1084	17	32	.	.	PUNCT
brainmatters-1084	18	1	early	early	ADJ
brainmatters-1084	18	2	initiation	initiation	NOUN
brainmatters-1084	18	3	of	of	ADP
brainmatters-1084	18	4	ert	ert	NOUN
brainmatters-1084	18	5	appears	appear	VERB
brainmatters-1084	18	6	to	to	PART
brainmatters-1084	18	7	bolster	bolster	VERB
brainmatters-1084	18	8	hippocampal	hippocampal	ADJ
brainmatters-1084	18	9	integrity	integrity	NOUN
brainmatters-1084	18	10	,	,	PUNCT
brainmatters-1084	18	11	thereby	thereby	ADV
brainmatters-1084	18	12	preventing	prevent	VERB
brainmatters-1084	18	13	functional	functional	ADJ
brainmatters-1084	18	14	decline	decline	NOUN
brainmatters-1084	18	15	in	in	ADP
brainmatters-1084	18	16	this	this	DET
brainmatters-1084	18	17	essential	essential	ADJ
brainmatters-1084	18	18	region	region	NOUN
brainmatters-1084	18	19	.	.	PUNCT
brainmatters-1084	19	1	the	the	DET
brainmatters-1084	19	2	prefrontal	prefrontal	ADJ
brainmatters-1084	19	3	cortex	cortex	NOUN
brainmatters-1084	19	4	the	the	DET
brainmatters-1084	19	5	prefrontal	prefrontal	ADJ
brainmatters-1084	19	6	cortex	cortex	NOUN
brainmatters-1084	19	7	is	be	AUX
brainmatters-1084	19	8	responsible	responsible	ADJ
brainmatters-1084	19	9	for	for	ADP
brainmatters-1084	19	10	executive	executive	ADJ
brainmatters-1084	19	11	functions	function	NOUN
brainmatters-1084	19	12	,	,	PUNCT
brainmatters-1084	19	13	including	include	VERB
brainmatters-1084	19	14	decision	decision	NOUN
brainmatters-1084	19	15	-	-	PUNCT
brainmatters-1084	19	16	making	making	NOUN
brainmatters-1084	19	17	,	,	PUNCT
brainmatters-1084	19	18	attention	attention	NOUN
brainmatters-1084	19	19	,	,	PUNCT
brainmatters-1084	19	20	and	and	CCONJ
brainmatters-1084	19	21	working	working	NOUN
brainmatters-1084	19	22	memory	memory	NOUN
brainmatters-1084	19	23	.	.	PUNCT
brainmatters-1084	20	1	ert	ert	PROPN
brainmatters-1084	20	2	can	can	AUX
brainmatters-1084	20	3	enhance	enhance	VERB
brainmatters-1084	20	4	prefrontal	prefrontal	ADJ
brainmatters-1084	20	5	cortex	cortex	NOUN
brainmatters-1084	20	6	function	function	NOUN
brainmatters-1084	20	7	,	,	PUNCT
brainmatters-1084	20	8	particularly	particularly	ADV
brainmatters-1084	20	9	in	in	ADP
brainmatters-1084	20	10	tasks	task	NOUN
brainmatters-1084	20	11	requiring	require	VERB
brainmatters-1084	20	12	cognitive	cognitive	ADJ
brainmatters-1084	20	13	flexibility	flexibility	NOUN
brainmatters-1084	20	14	(	(	PUNCT
brainmatters-1084	20	15	wang	wang	PROPN
brainmatters-1084	20	16	et	et	PROPN
brainmatters-1084	20	17	al	al	PROPN
brainmatters-1084	20	18	.	.	PROPN
brainmatters-1084	20	19	,	,	PUNCT
brainmatters-1084	20	20	2015	2015	NUM
brainmatters-1084	20	21	)	)	PUNCT
brainmatters-1084	20	22	.	.	PUNCT
brainmatters-1084	21	1	estrogen	estrogen	NOUN
brainmatters-1084	21	2	increases	increase	VERB
brainmatters-1084	21	3	synaptic	synaptic	ADJ
brainmatters-1084	21	4	density	density	NOUN
brainmatters-1084	21	5	and	and	CCONJ
brainmatters-1084	21	6	improves	improve	VERB
brainmatters-1084	21	7	neurotransmission	neurotransmission	NOUN
brainmatters-1084	21	8	efficiency	efficiency	NOUN
brainmatters-1084	21	9	,	,	PUNCT
brainmatters-1084	21	10	facilitating	facilitate	VERB
brainmatters-1084	21	11	cognitive	cognitive	ADJ
brainmatters-1084	21	12	processes	process	NOUN
brainmatters-1084	21	13	crucial	crucial	ADJ
brainmatters-1084	21	14	for	for	ADP
brainmatters-1084	21	15	complex	complex	ADJ
brainmatters-1084	21	16	decision	decision	NOUN
brainmatters-1084	21	17	-	-	PUNCT
brainmatters-1084	21	18	making	making	NOUN
brainmatters-1084	21	19	(	(	PUNCT
brainmatters-1084	21	20	turek	turek	NOUN
brainmatters-1084	21	21	&	&	CCONJ
brainmatters-1084	21	22	gąsior	gąsior	PROPN
brainmatters-1084	21	23	,	,	PUNCT
brainmatters-1084	21	24	2023	2023	NUM
brainmatters-1084	21	25	)	)	PUNCT
brainmatters-1084	21	26	.	.	PUNCT
brainmatters-1084	22	1	this	this	DET
brainmatters-1084	22	2	enhancement	enhancement	NOUN
brainmatters-1084	22	3	occurs	occur	VERB
brainmatters-1084	22	4	through	through	ADP
brainmatters-1084	22	5	estrogen	estrogen	NOUN
brainmatters-1084	22	6	's	's	PART
brainmatters-1084	22	7	modulation	modulation	NOUN
brainmatters-1084	22	8	of	of	ADP
brainmatters-1084	22	9	gabaergic	gabaergic	ADJ
brainmatters-1084	22	10	and	and	CCONJ
brainmatters-1084	22	11	glutamatergic	glutamatergic	ADJ
brainmatters-1084	22	12	signaling	signal	VERB
brainmatters-1084	22	13	pathways	pathway	NOUN
brainmatters-1084	22	14	,	,	PUNCT
brainmatters-1084	22	15	which	which	PRON
brainmatters-1084	22	16	contribute	contribute	VERB
brainmatters-1084	22	17	to	to	ADP
brainmatters-1084	22	18	improved	improved	ADJ
brainmatters-1084	22	19	cognitive	cognitive	ADJ
brainmatters-1084	22	20	performance	performance	NOUN
brainmatters-1084	22	21	(	(	PUNCT
brainmatters-1084	22	22	daniel	daniel	PROPN
brainmatters-1084	22	23	&	&	CCONJ
brainmatters-1084	22	24	dohanich	dohanich	PROPN
brainmatters-1084	22	25	,	,	PUNCT
brainmatters-1084	22	26	2015	2015	NUM
brainmatters-1084	22	27	)	)	PUNCT
brainmatters-1084	22	28	.	.	PUNCT
brainmatters-1084	23	1	by	by	ADP
brainmatters-1084	23	2	sustaining	sustain	VERB
brainmatters-1084	23	3	these	these	DET
brainmatters-1084	23	4	neurobiological	neurobiological	ADJ
brainmatters-1084	23	5	timing	timing	NOUN
brainmatters-1084	23	6	of	of	ADP
brainmatters-1084	23	7	estrogen	estrogen	NOUN
brainmatters-1084	23	8	replacement	replacement	NOUN
brainmatters-1084	23	9	therapy	therapy	NOUN
brainmatters-1084	23	10	:	:	PUNCT
brainmatters-1084	23	11	the	the	DET
brainmatters-1084	23	12	critical	critical	ADJ
brainmatters-1084	23	13	window	window	NOUN
brainmatters-1084	23	14	hypothesis	hypothesis	NOUN
brainmatters-1084	23	15	the	the	DET
brainmatters-1084	23	16	critical	critical	ADJ
brainmatters-1084	23	17	window	window	NOUN
brainmatters-1084	23	18	hypothesis	hypothesis	NOUN
brainmatters-1084	23	19	proposes	propose	VERB
brainmatters-1084	23	20	that	that	SCONJ
brainmatters-1084	23	21	the	the	DET
brainmatters-1084	23	22	cognitive	cognitive	ADJ
brainmatters-1084	23	23	benefits	benefit	NOUN
brainmatters-1084	23	24	of	of	ADP
brainmatters-1084	23	25	ert	ert	NOUN
brainmatters-1084	23	26	are	be	AUX
brainmatters-1084	23	27	maximized	maximize	VERB
brainmatters-1084	23	28	when	when	SCONJ
brainmatters-1084	23	29	initiated	initiate	VERB
brainmatters-1084	23	30	during	during	ADP
brainmatters-1084	23	31	a	a	DET
brainmatters-1084	23	32	narrow	narrow	ADJ
brainmatters-1084	23	33	window	window	NOUN
brainmatters-1084	23	34	around	around	ADP
brainmatters-1084	23	35	menopause	menopause	NOUN
brainmatters-1084	23	36	onset	onset	NOUN
brainmatters-1084	23	37	.	.	PUNCT
brainmatters-1084	24	1	this	this	DET
brainmatters-1084	24	2	timing	timing	NOUN
brainmatters-1084	24	3	aligns	align	VERB
brainmatters-1084	24	4	with	with	ADP
brainmatters-1084	24	5	estrogen	estrogen	NOUN
brainmatters-1084	24	6	’s	’s	PART
brainmatters-1084	24	7	neurobiological	neurobiological	ADJ
brainmatters-1084	24	8	effects	effect	NOUN
brainmatters-1084	24	9	on	on	ADP
brainmatters-1084	24	10	brain	brain	NOUN
brainmatters-1084	24	11	health	health	NOUN
brainmatters-1084	24	12	,	,	PUNCT
brainmatters-1084	24	13	as	as	SCONJ
brainmatters-1084	24	14	early	early	ADJ
brainmatters-1084	24	15	intervention	intervention	NOUN
brainmatters-1084	24	16	supports	support	VERB
brainmatters-1084	24	17	neurogenesis	neurogenesis	NOUN
brainmatters-1084	24	18	,	,	PUNCT
brainmatters-1084	24	19	mitochondrial	mitochondrial	ADJ
brainmatters-1084	24	20	function	function	NOUN
brainmatters-1084	24	21	furthermore	furthermore	ADV
brainmatters-1084	24	22	,	,	PUNCT
brainmatters-1084	24	23	estrogen	estrogen	NOUN
brainmatters-1084	24	24	facilitates	facilitate	VERB
brainmatters-1084	24	25	the	the	DET
brainmatters-1084	24	26	conversion	conversion	NOUN
brainmatters-1084	24	27	of	of	ADP
brainmatters-1084	24	28	neural	neural	ADJ
brainmatters-1084	24	29	stem	stem	NOUN
brainmatters-1084	24	30	cells	cell	NOUN
brainmatters-1084	24	31	into	into	ADP
brainmatters-1084	24	32	neurons	neuron	NOUN
brainmatters-1084	24	33	,	,	PUNCT
brainmatters-1084	24	34	enhancing	enhance	VERB
brainmatters-1084	24	35	the	the	DET
brainmatters-1084	24	36	capacity	capacity	NOUN
brainmatters-1084	24	37	for	for	ADP
brainmatters-1084	24	38	neurogenesis	neurogenesis	NOUN
brainmatters-1084	24	39	(	(	PUNCT
brainmatters-1084	24	40	wang	wang	PROPN
brainmatters-1084	24	41	et	et	PROPN
brainmatters-1084	24	42	al	al	PROPN
brainmatters-1084	24	43	.	.	PROPN
brainmatters-1084	24	44	,	,	PUNCT
brainmatters-1084	24	45	2015	2015	NUM
brainmatters-1084	24	46	)	)	PUNCT
brainmatters-1084	24	47	.	.	PUNCT
brainmatters-1084	25	1	synaptic	synaptic	ADJ
brainmatters-1084	25	2	plasticity	plasticity	NOUN
brainmatters-1084	25	3	and	and	CCONJ
brainmatters-1084	25	4	neurotransmitter	neurotransmitter	NOUN
brainmatters-1084	25	5	modulation	modulation	NOUN
brainmatters-1084	25	6	synaptic	synaptic	ADJ
brainmatters-1084	25	7	plasticity	plasticity	NOUN
brainmatters-1084	25	8	,	,	PUNCT
brainmatters-1084	25	9	the	the	DET
brainmatters-1084	25	10	brain	brain	NOUN
brainmatters-1084	25	11	’s	’s	PART
brainmatters-1084	25	12	ability	ability	NOUN
brainmatters-1084	25	13	to	to	PART
brainmatters-1084	25	14	strengthen	strengthen	VERB
brainmatters-1084	25	15	or	or	CCONJ
brainmatters-1084	25	16	weaken	weaken	VERB
brainmatters-1084	25	17	connections	connection	NOUN
brainmatters-1084	25	18	between	between	ADP
brainmatters-1084	25	19	neurons	neuron	NOUN
brainmatters-1084	25	20	,	,	PUNCT
brainmatters-1084	25	21	is	be	AUX
brainmatters-1084	25	22	central	central	ADJ
brainmatters-1084	25	23	to	to	ADP
brainmatters-1084	25	24	learning	learning	NOUN
brainmatters-1084	25	25	and	and	CCONJ
brainmatters-1084	25	26	memory	memory	NOUN
brainmatters-1084	25	27	.	.	PUNCT
brainmatters-1084	26	1	estrogen	estrogen	NOUN
brainmatters-1084	26	2	enhances	enhance	VERB
brainmatters-1084	26	3	synaptic	synaptic	ADJ
brainmatters-1084	26	4	plasticity	plasticity	NOUN
brainmatters-1084	26	5	by	by	ADP
brainmatters-1084	26	6	modulating	modulate	VERB
brainmatters-1084	26	7	glutamatergic	glutamatergic	ADJ
brainmatters-1084	26	8	and	and	CCONJ
brainmatters-1084	26	9	cholinergic	cholinergic	ADJ
brainmatters-1084	26	10	neurotransmission	neurotransmission	NOUN
brainmatters-1084	26	11	,	,	PUNCT
brainmatters-1084	26	12	which	which	PRON
brainmatters-1084	26	13	supports	support	VERB
brainmatters-1084	26	14	efficient	efficient	ADJ
brainmatters-1084	26	15	signal	signal	NOUN
brainmatters-1084	26	16	transmission	transmission	NOUN
brainmatters-1084	26	17	across	across	ADP
brainmatters-1084	26	18	neurons	neuron	NOUN
brainmatters-1084	26	19	(	(	PUNCT
brainmatters-1084	26	20	daniel	daniel	PROPN
brainmatters-1084	26	21	&	&	CCONJ
brainmatters-1084	26	22	dohanich	dohanich	PROPN
brainmatters-1084	26	23	,	,	PUNCT
brainmatters-1084	26	24	2015	2015	NUM
brainmatters-1084	26	25	)	)	PUNCT
brainmatters-1084	26	26	.	.	PUNCT
brainmatters-1084	27	1	estrogen	estrogen	NOUN
brainmatters-1084	27	2	also	also	ADV
brainmatters-1084	27	3	influences	influence	VERB
brainmatters-1084	27	4	nmda	nmda	ADJ
brainmatters-1084	27	5	receptor	receptor	NOUN
brainmatters-1084	27	6	activity	activity	NOUN
brainmatters-1084	27	7	,	,	PUNCT
brainmatters-1084	27	8	which	which	PRON
brainmatters-1084	27	9	plays	play	VERB
brainmatters-1084	27	10	a	a	DET
brainmatters-1084	27	11	key	key	ADJ
brainmatters-1084	27	12	role	role	NOUN
brainmatters-1084	27	13	in	in	ADP
brainmatters-1084	27	14	synaptic	synaptic	ADJ
brainmatters-1084	27	15	strengthening	strengthening	NOUN
brainmatters-1084	27	16	during	during	ADP
brainmatters-1084	27	17	memory	memory	NOUN
brainmatters-1084	27	18	encoding	encoding	NOUN
brainmatters-1084	27	19	and	and	CCONJ
brainmatters-1084	27	20	retrieval	retrieval	NOUN
brainmatters-1084	27	21	.	.	PUNCT
brainmatters-1084	28	1	by	by	ADP
brainmatters-1084	28	2	supporting	support	VERB
brainmatters-1084	28	3	these	these	DET
brainmatters-1084	28	4	mechanisms	mechanism	NOUN
brainmatters-1084	28	5	,	,	PUNCT
brainmatters-1084	28	6	estrogen	estrogen	NOUN
brainmatters-1084	28	7	fosters	foster	VERB
brainmatters-1084	28	8	an	an	DET
brainmatters-1084	28	9	environment	environment	NOUN
brainmatters-1084	28	10	conducive	conducive	ADJ
brainmatters-1084	28	11	to	to	ADP
brainmatters-1084	28	12	cognitive	cognitive	ADJ
brainmatters-1084	28	13	agility	agility	NOUN
brainmatters-1084	28	14	and	and	CCONJ
brainmatters-1084	28	15	long	long	ADJ
brainmatters-1084	28	16	-	-	PUNCT
brainmatters-1084	28	17	term	term	NOUN
brainmatters-1084	28	18	memory	memory	NOUN
brainmatters-1084	28	19	storage	storage	NOUN
brainmatters-1084	28	20	.	.	PUNCT
brainmatters-1084	29	1	amyloid	amyloid	NOUN
brainmatters-1084	29	2	-	-	PUNCT
brainmatters-1084	29	3	beta	beta	NOUN
brainmatters-1084	29	4	clearance	clearance	NOUN
brainmatters-1084	29	5	and	and	CCONJ
brainmatters-1084	29	6	tau	tau	PROPN
brainmatters-1084	29	7	pathology	pathology	NOUN
brainmatters-1084	29	8	reduction	reduction	NOUN
brainmatters-1084	29	9	the	the	DET
brainmatters-1084	29	10	accumulation	accumulation	NOUN
brainmatters-1084	29	11	of	of	ADP
brainmatters-1084	29	12	amyloid	amyloid	NOUN
brainmatters-1084	29	13	-	-	PUNCT
brainmatters-1084	29	14	beta	beta	NOUN
brainmatters-1084	29	15	(	(	PUNCT
brainmatters-1084	29	16	aβ	aβ	NOUN
brainmatters-1084	29	17	)	)	PUNCT
brainmatters-1084	29	18	plaques	plaque	NOUN
brainmatters-1084	29	19	and	and	CCONJ
brainmatters-1084	29	20	tau	tau	PROPN
brainmatters-1084	29	21	tangles	tangle	NOUN
brainmatters-1084	29	22	are	be	AUX
brainmatters-1084	29	23	hallmarks	hallmark	NOUN
brainmatters-1084	29	24	of	of	ADP
brainmatters-1084	29	25	alzheimer	alzheimer	PROPN
brainmatters-1084	29	26	’s	’s	PART
brainmatters-1084	29	27	disease	disease	NOUN
brainmatters-1084	29	28	pathology	pathology	NOUN
brainmatters-1084	29	29	.	.	PUNCT
brainmatters-1084	30	1	estrogen	estrogen	PROPN
brainmatters-1084	30	2	contributes	contribute	VERB
brainmatters-1084	30	3	to	to	ADP
brainmatters-1084	30	4	the	the	DET
brainmatters-1084	30	5	enzymatic	enzymatic	ADJ
brainmatters-1084	30	6	breakdown	breakdown	NOUN
brainmatters-1084	30	7	of	of	ADP
brainmatters-1084	30	8	aβ	aβ	DET
brainmatters-1084	30	9	plaques	plaque	NOUN
brainmatters-1084	30	10	and	and	CCONJ
brainmatters-1084	30	11	inhibits	inhibit	VERB
brainmatters-1084	30	12	tau	tau	PROPN
brainmatters-1084	30	13	hyperphosphorylation	hyperphosphorylation	NOUN
brainmatters-1084	30	14	,	,	PUNCT
brainmatters-1084	30	15	thus	thus	ADV
brainmatters-1084	30	16	reducing	reduce	VERB
brainmatters-1084	30	17	the	the	DET
brainmatters-1084	30	18	risk	risk	NOUN
brainmatters-1084	30	19	of	of	ADP
brainmatters-1084	30	20	these	these	DET
brainmatters-1084	30	21	toxic	toxic	ADJ
brainmatters-1084	30	22	accumulations	accumulation	NOUN
brainmatters-1084	30	23	(	(	PUNCT
brainmatters-1084	30	24	mosconi	mosconi	PROPN
brainmatters-1084	30	25	et	et	PROPN
brainmatters-1084	30	26	al	al	PROPN
brainmatters-1084	30	27	.	.	PROPN
brainmatters-1084	30	28	,	,	PUNCT
brainmatters-1084	30	29	2017	2017	NUM
brainmatters-1084	30	30	;	;	PUNCT
brainmatters-1084	30	31	maki	maki	PROPN
brainmatters-1084	30	32	&	&	CCONJ
brainmatters-1084	30	33	henderson	henderson	PROPN
brainmatters-1084	30	34	,	,	PUNCT
brainmatters-1084	30	35	2020	2020	NUM
brainmatters-1084	30	36	)	)	PUNCT
brainmatters-1084	30	37	.	.	PUNCT
brainmatters-1084	31	1	recent	recent	ADJ
brainmatters-1084	31	2	findings	finding	NOUN
brainmatters-1084	31	3	suggest	suggest	VERB
brainmatters-1084	31	4	that	that	SCONJ
brainmatters-1084	31	5	estrogen	estrogen	NOUN
brainmatters-1084	31	6	enhances	enhance	VERB
brainmatters-1084	31	7	the	the	DET
brainmatters-1084	31	8	expression	expression	NOUN
brainmatters-1084	31	9	of	of	ADP
brainmatters-1084	31	10	proteins	protein	NOUN
brainmatters-1084	31	11	involved	involve	VERB
brainmatters-1084	31	12	in	in	ADP
brainmatters-1084	31	13	aβ	aβ	DET
brainmatters-1084	31	14	clearance	clearance	NOUN
brainmatters-1084	31	15	,	,	PUNCT
brainmatters-1084	31	16	such	such	ADJ
brainmatters-1084	31	17	as	as	ADP
brainmatters-1084	31	18	apolipoprotein	apolipoprotein	ADJ
brainmatters-1084	31	19	e	e	PROPN
brainmatters-1084	31	20	(	(	PUNCT
brainmatters-1084	31	21	apoe	apoe	ADJ
brainmatters-1084	31	22	)	)	PUNCT
brainmatters-1084	31	23	,	,	PUNCT
brainmatters-1084	31	24	and	and	CCONJ
brainmatters-1084	31	25	promotes	promote	VERB
brainmatters-1084	31	26	the	the	DET
brainmatters-1084	31	27	function	function	NOUN
brainmatters-1084	31	28	of	of	ADP
brainmatters-1084	31	29	microglia	microglia	NOUN
brainmatters-1084	31	30	,	,	PUNCT
brainmatters-1084	31	31	the	the	DET
brainmatters-1084	31	32	brain	brain	NOUN
brainmatters-1084	31	33	's	's	PART
brainmatters-1084	31	34	resident	resident	ADJ
brainmatters-1084	31	35	immune	immune	ADJ
brainmatters-1084	31	36	cells	cell	NOUN
brainmatters-1084	31	37	,	,	PUNCT
brainmatters-1084	31	38	in	in	ADP
brainmatters-1084	31	39	phagocytosing	phagocytose	VERB
brainmatters-1084	31	40	aβ	aβ	PRON
brainmatters-1084	31	41	deposits	deposit	NOUN
brainmatters-1084	31	42	(	(	PUNCT
brainmatters-1084	31	43	kuhlmann	kuhlmann	PROPN
brainmatters-1084	31	44	et	et	NOUN
brainmatters-1084	31	45	al	al	PROPN
brainmatters-1084	31	46	.	.	PROPN
brainmatters-1084	31	47	,	,	PUNCT
brainmatters-1084	31	48	2020	2020	NUM
brainmatters-1084	31	49	)	)	PUNCT
brainmatters-1084	31	50	.	.	PUNCT
brainmatters-1084	32	1	by	by	ADP
brainmatters-1084	32	2	initiating	initiate	VERB
brainmatters-1084	32	3	ert	ert	NOUN
brainmatters-1084	32	4	within	within	ADP
brainmatters-1084	32	5	the	the	DET
brainmatters-1084	32	6	critical	critical	ADJ
brainmatters-1084	32	7	window	window	NOUN
brainmatters-1084	32	8	,	,	PUNCT
brainmatters-1084	32	9	these	these	DET
brainmatters-1084	32	10	neuroprotective	neuroprotective	ADJ
brainmatters-1084	32	11	processes	process	NOUN
brainmatters-1084	32	12	are	be	AUX
brainmatters-1084	32	13	more	more	ADV
brainmatters-1084	32	14	likely	likely	ADJ
brainmatters-1084	32	15	to	to	PART
brainmatters-1084	32	16	be	be	AUX
brainmatters-1084	32	17	effective	effective	ADJ
brainmatters-1084	32	18	in	in	ADP
brainmatters-1084	32	19	staving	stave	VERB
brainmatters-1084	32	20	off	off	ADP
brainmatters-1084	32	21	aβ	aβ	ADV
brainmatters-1084	32	22	-	-	PUNCT
brainmatters-1084	32	23	related	relate	VERB
brainmatters-1084	32	24	pathology	pathology	NOUN
brainmatters-1084	32	25	and	and	CCONJ
brainmatters-1084	32	26	maintaining	maintain	VERB
brainmatters-1084	32	27	healthy	healthy	ADJ
brainmatters-1084	32	28	neural	neural	ADJ
brainmatters-1084	32	29	networks	network	NOUN
brainmatters-1084	32	30	.	.	PUNCT
brainmatters-1084	33	1	an	an	DET
brainmatters-1084	33	2	estrogen	estrogen	NOUN
brainmatters-1084	33	3	-	-	PUNCT
brainmatters-1084	33	4	deprived	deprive	VERB
brainmatters-1084	33	5	state	state	NOUN
brainmatters-1084	33	6	can	can	AUX
brainmatters-1084	33	7	lead	lead	VERB
brainmatters-1084	33	8	to	to	ADP
brainmatters-1084	33	9	reduced	reduce	VERB
brainmatters-1084	33	10	bdnf	bdnf	ADJ
brainmatters-1084	33	11	levels	level	NOUN
brainmatters-1084	33	12	,	,	PUNCT
brainmatters-1084	33	13	impairing	impair	VERB
brainmatters-1084	33	14	neurogenesis	neurogenesis	NOUN
brainmatters-1084	33	15	and	and	CCONJ
brainmatters-1084	33	16	contributing	contribute	VERB
brainmatters-1084	33	17	to	to	ADP
brainmatters-1084	33	18	cognitive	cognitive	ADJ
brainmatters-1084	33	19	decline	decline	NOUN
brainmatters-1084	33	20	(	(	PUNCT
brainmatters-1084	33	21	turek	turek	NOUN
brainmatters-1084	33	22	&	&	CCONJ
brainmatters-1084	33	23	gąsior	gąsior	PROPN
brainmatters-1084	33	24	,	,	PUNCT
brainmatters-1084	33	25	2023	2023	NUM
brainmatters-1084	33	26	)	)	PUNCT
brainmatters-1084	33	27	.	.	PUNCT
brainmatters-1084	34	1	brain	brain	NOUN
brainmatters-1084	34	2	matters	matter	NOUN
brainmatters-1084	34	3	vol	vol	NOUN
brainmatters-1084	34	4	.	.	PROPN
brainmatters-1084	34	5	8	8	NUM
brainmatters-1084	34	6	2025	2025	NUM
brainmatters-1084	34	7	neurobiological	neurobiological	ADJ
brainmatters-1084	34	8	functions	function	NOUN
brainmatters-1084	34	9	,	,	PUNCT
brainmatters-1084	34	10	estrogen	estrogen	NOUN
brainmatters-1084	34	11	mitigates	mitigate	VERB
brainmatters-1084	34	12	cognitive	cognitive	ADJ
brainmatters-1084	34	13	aging	aging	NOUN
brainmatters-1084	34	14	,	,	PUNCT
brainmatters-1084	34	15	particularly	particularly	ADV
brainmatters-1084	34	16	in	in	ADP
brainmatters-1084	34	17	domains	domain	NOUN
brainmatters-1084	34	18	that	that	PRON
brainmatters-1084	34	19	decline	decline	VERB
brainmatters-1084	34	20	significantly	significantly	ADV
brainmatters-1084	34	21	with	with	ADP
brainmatters-1084	34	22	age	age	NOUN
brainmatters-1084	34	23	.	.	PUNCT
brainmatters-1084	35	1	neurobiological	neurobiological	ADJ
brainmatters-1084	35	2	mechanisms	mechanism	NOUN
brainmatters-1084	35	3	of	of	ADP
brainmatters-1084	35	4	estrogen	estrogen	NOUN
brainmatters-1084	35	5	in	in	ADP
brainmatters-1084	35	6	the	the	DET
brainmatters-1084	35	7	brain	brain	NOUN
brainmatters-1084	35	8	estrogen	estrogen	NOUN
brainmatters-1084	35	9	exerts	exert	VERB
brainmatters-1084	35	10	its	its	PRON
brainmatters-1084	35	11	neuroprotective	neuroprotective	ADJ
brainmatters-1084	35	12	effects	effect	NOUN
brainmatters-1084	35	13	through	through	ADP
brainmatters-1084	35	14	several	several	ADJ
brainmatters-1084	35	15	cellular	cellular	ADJ
brainmatters-1084	35	16	and	and	CCONJ
brainmatters-1084	35	17	molecular	molecular	ADJ
brainmatters-1084	35	18	pathways	pathway	NOUN
brainmatters-1084	35	19	,	,	PUNCT
brainmatters-1084	35	20	including	include	VERB
brainmatters-1084	35	21	mitochondrial	mitochondrial	ADJ
brainmatters-1084	35	22	function	function	NOUN
brainmatters-1084	35	23	,	,	PUNCT
brainmatters-1084	35	24	neurogenesis	neurogenesis	NOUN
brainmatters-1084	35	25	,	,	PUNCT
brainmatters-1084	35	26	synaptic	synaptic	ADJ
brainmatters-1084	35	27	plasticity	plasticity	NOUN
brainmatters-1084	35	28	,	,	PUNCT
brainmatters-1084	35	29	and	and	CCONJ
brainmatters-1084	35	30	amyloidbeta	amyloidbeta	ADJ
brainmatters-1084	35	31	clearance	clearance	NOUN
brainmatters-1084	35	32	.	.	PUNCT
brainmatters-1084	36	1	these	these	DET
brainmatters-1084	36	2	pathways	pathway	NOUN
brainmatters-1084	36	3	collectively	collectively	ADV
brainmatters-1084	36	4	contribute	contribute	VERB
brainmatters-1084	36	5	to	to	ADP
brainmatters-1084	36	6	cognitive	cognitive	ADJ
brainmatters-1084	36	7	resilience	resilience	NOUN
brainmatters-1084	36	8	and	and	CCONJ
brainmatters-1084	36	9	reduce	reduce	VERB
brainmatters-1084	36	10	the	the	DET
brainmatters-1084	36	11	risk	risk	NOUN
brainmatters-1084	36	12	of	of	ADP
brainmatters-1084	36	13	neurodegenerative	neurodegenerative	ADJ
brainmatters-1084	36	14	diseases	disease	NOUN
brainmatters-1084	36	15	.	.	PUNCT
brainmatters-1084	37	1	mitochondrial	mitochondrial	ADJ
brainmatters-1084	37	2	health	health	NOUN
brainmatters-1084	37	3	and	and	CCONJ
brainmatters-1084	37	4	oxidative	oxidative	ADJ
brainmatters-1084	37	5	stress	stress	NOUN
brainmatters-1084	37	6	reduction	reduction	NOUN
brainmatters-1084	37	7	mitochondria	mitochondria	NOUN
brainmatters-1084	37	8	are	be	AUX
brainmatters-1084	37	9	essential	essential	ADJ
brainmatters-1084	37	10	for	for	ADP
brainmatters-1084	37	11	meeting	meet	VERB
brainmatters-1084	37	12	the	the	DET
brainmatters-1084	37	13	high	high	ADJ
brainmatters-1084	37	14	energy	energy	NOUN
brainmatters-1084	37	15	demands	demand	NOUN
brainmatters-1084	37	16	of	of	ADP
brainmatters-1084	37	17	brain	brain	NOUN
brainmatters-1084	37	18	cells	cell	NOUN
brainmatters-1084	37	19	.	.	PUNCT
brainmatters-1084	38	1	estrogen	estrogen	NOUN
brainmatters-1084	38	2	enhances	enhance	VERB
brainmatters-1084	38	3	mitochondrial	mitochondrial	ADJ
brainmatters-1084	38	4	function	function	NOUN
brainmatters-1084	38	5	by	by	ADP
brainmatters-1084	38	6	promoting	promote	VERB
brainmatters-1084	38	7	atp	atp	NOUN
brainmatters-1084	38	8	production	production	NOUN
brainmatters-1084	38	9	and	and	CCONJ
brainmatters-1084	38	10	activating	activate	VERB
brainmatters-1084	38	11	antioxidant	antioxidant	ADJ
brainmatters-1084	38	12	systems	system	NOUN
brainmatters-1084	38	13	that	that	PRON
brainmatters-1084	38	14	neutralize	neutralize	VERB
brainmatters-1084	38	15	free	free	ADJ
brainmatters-1084	38	16	radicals	radical	NOUN
brainmatters-1084	38	17	,	,	PUNCT
brainmatters-1084	38	18	thereby	thereby	ADV
brainmatters-1084	38	19	reducing	reduce	VERB
brainmatters-1084	38	20	oxidative	oxidative	ADJ
brainmatters-1084	38	21	stress	stress	NOUN
brainmatters-1084	38	22	(	(	PUNCT
brainmatters-1084	38	23	brinton	brinton	NOUN
brainmatters-1084	38	24	,	,	PUNCT
brainmatters-1084	38	25	2013	2013	NUM
brainmatters-1084	38	26	;	;	PUNCT
brainmatters-1084	38	27	maki	maki	PROPN
brainmatters-1084	38	28	&	&	CCONJ
brainmatters-1084	38	29	henderson	henderson	PROPN
brainmatters-1084	38	30	,	,	PUNCT
brainmatters-1084	38	31	2020	2020	NUM
brainmatters-1084	38	32	)	)	PUNCT
brainmatters-1084	38	33	.	.	PUNCT
brainmatters-1084	39	1	estrogen	estrogen	PROPN
brainmatters-1084	39	2	's	's	PART
brainmatters-1084	39	3	role	role	NOUN
brainmatters-1084	39	4	in	in	ADP
brainmatters-1084	39	5	upregulating	upregulating	ADJ
brainmatters-1084	39	6	antioxidant	antioxidant	ADJ
brainmatters-1084	39	7	enzymes	enzyme	NOUN
brainmatters-1084	39	8	such	such	ADJ
brainmatters-1084	39	9	as	as	ADP
brainmatters-1084	39	10	superoxide	superoxide	NOUN
brainmatters-1084	39	11	dismutase	dismutase	NOUN
brainmatters-1084	39	12	(	(	PUNCT
brainmatters-1084	39	13	sod	sod	NOUN
brainmatters-1084	39	14	)	)	PUNCT
brainmatters-1084	39	15	and	and	CCONJ
brainmatters-1084	39	16	glutathione	glutathione	NOUN
brainmatters-1084	39	17	peroxidasehelps	peroxidasehelp	NOUN
brainmatters-1084	39	18	protect	protect	VERB
brainmatters-1084	39	19	neurons	neuron	NOUN
brainmatters-1084	39	20	from	from	ADP
brainmatters-1084	39	21	oxidative	oxidative	ADJ
brainmatters-1084	39	22	damage	damage	NOUN
brainmatters-1084	39	23	(	(	PUNCT
brainmatters-1084	39	24	kumar	kumar	PROPN
brainmatters-1084	39	25	et	et	PROPN
brainmatters-1084	39	26	al	al	PROPN
brainmatters-1084	39	27	.	.	PROPN
brainmatters-1084	39	28	,	,	PUNCT
brainmatters-1084	39	29	2019	2019	NUM
brainmatters-1084	39	30	)	)	PUNCT
brainmatters-1084	39	31	.	.	PUNCT
brainmatters-1084	40	1	this	this	DET
brainmatters-1084	40	2	mitochondrial	mitochondrial	ADJ
brainmatters-1084	40	3	support	support	NOUN
brainmatters-1084	40	4	is	be	AUX
brainmatters-1084	40	5	especially	especially	ADV
brainmatters-1084	40	6	relevant	relevant	ADJ
brainmatters-1084	40	7	in	in	ADP
brainmatters-1084	40	8	the	the	DET
brainmatters-1084	40	9	hippocampus	hippocampus	NOUN
brainmatters-1084	40	10	and	and	CCONJ
brainmatters-1084	40	11	cortex	cortex	NOUN
brainmatters-1084	40	12	,	,	PUNCT
brainmatters-1084	40	13	where	where	SCONJ
brainmatters-1084	40	14	energy	energy	NOUN
brainmatters-1084	40	15	demands	demand	NOUN
brainmatters-1084	40	16	are	be	AUX
brainmatters-1084	40	17	heightened	heighten	VERB
brainmatters-1084	40	18	due	due	ADJ
brainmatters-1084	40	19	to	to	ADP
brainmatters-1084	40	20	intensive	intensive	ADJ
brainmatters-1084	40	21	synaptic	synaptic	ADJ
brainmatters-1084	40	22	activity	activity	NOUN
brainmatters-1084	40	23	.	.	PUNCT
brainmatters-1084	41	1	neurogenesis	neurogenesis	NOUN
brainmatters-1084	41	2	and	and	CCONJ
brainmatters-1084	41	3	brain	brain	NOUN
brainmatters-1084	41	4	-	-	PUNCT
brainmatters-1084	41	5	derived	derive	VERB
brainmatters-1084	41	6	neurotrophic	neurotrophic	ADJ
brainmatters-1084	41	7	factor	factor	NOUN
brainmatters-1084	41	8	(	(	PUNCT
brainmatters-1084	41	9	bdnf	bdnf	ADJ
brainmatters-1084	41	10	)	)	PUNCT
brainmatters-1084	41	11	regulation	regulation	NOUN
brainmatters-1084	41	12	estrogen	estrogen	NOUN
brainmatters-1084	41	13	stimulates	stimulate	NOUN
brainmatters-1084	41	14	neurogenesis	neurogenesis	NOUN
brainmatters-1084	41	15	in	in	ADP
brainmatters-1084	41	16	the	the	DET
brainmatters-1084	41	17	adult	adult	NOUN
brainmatters-1084	41	18	hippocampus	hippocampus	NOUN
brainmatters-1084	41	19	,	,	PUNCT
brainmatters-1084	41	20	partly	partly	ADV
brainmatters-1084	41	21	by	by	ADP
brainmatters-1084	41	22	increasing	increase	VERB
brainmatters-1084	41	23	levels	level	NOUN
brainmatters-1084	41	24	of	of	ADP
brainmatters-1084	41	25	brain	brain	NOUN
brainmatters-1084	41	26	-	-	PUNCT
brainmatters-1084	41	27	derived	derive	VERB
brainmatters-1084	41	28	neurotrophic	neurotrophic	ADJ
brainmatters-1084	41	29	factor	factor	NOUN
brainmatters-1084	41	30	(	(	PUNCT
brainmatters-1084	41	31	bdnf	bdnf	PROPN
brainmatters-1084	41	32	)	)	PUNCT
brainmatters-1084	41	33	,	,	PUNCT
brainmatters-1084	41	34	a	a	DET
brainmatters-1084	41	35	protein	protein	NOUN
brainmatters-1084	41	36	crucial	crucial	ADJ
brainmatters-1084	41	37	for	for	ADP
brainmatters-1084	41	38	neuron	neuron	PROPN
brainmatters-1084	41	39	survival	survival	NOUN
brainmatters-1084	41	40	,	,	PUNCT
brainmatters-1084	41	41	growth	growth	NOUN
brainmatters-1084	41	42	,	,	PUNCT
brainmatters-1084	41	43	and	and	CCONJ
brainmatters-1084	41	44	synaptic	synaptic	ADJ
brainmatters-1084	41	45	plasticity	plasticity	NOUN
brainmatters-1084	41	46	(	(	PUNCT
brainmatters-1084	41	47	gibbs	gibbs	PROPN
brainmatters-1084	41	48	et	et	PROPN
brainmatters-1084	41	49	al	al	PROPN
brainmatters-1084	41	50	.	.	PROPN
brainmatters-1084	41	51	,	,	PUNCT
brainmatters-1084	41	52	2000	2000	NUM
brainmatters-1084	41	53	)	)	PUNCT
brainmatters-1084	41	54	.	.	PUNCT
brainmatters-1084	42	1	bdnf	bdnf	PROPN
brainmatters-1084	42	2	not	not	PART
brainmatters-1084	42	3	only	only	ADV
brainmatters-1084	42	4	supports	support	VERB
brainmatters-1084	42	5	memory	memory	NOUN
brainmatters-1084	42	6	processes	process	NOUN
brainmatters-1084	42	7	but	but	CCONJ
brainmatters-1084	42	8	also	also	ADV
brainmatters-1084	42	9	enhances	enhance	VERB
brainmatters-1084	42	10	cognitive	cognitive	ADJ
brainmatters-1084	42	11	flexibility	flexibility	NOUN
brainmatters-1084	42	12	,	,	PUNCT
brainmatters-1084	42	13	which	which	PRON
brainmatters-1084	42	14	tends	tend	VERB
brainmatters-1084	42	15	to	to	PART
brainmatters-1084	42	16	decline	decline	VERB
brainmatters-1084	42	17	during	during	ADP
brainmatters-1084	42	18	aging	aging	NOUN
brainmatters-1084	42	19	.	.	PUNCT
brainmatters-1084	43	1	anestrogendep	anestrogendep	PROPN
brainmatters-1084	43	2	12	12	NUM
brainmatters-1084	43	3	figure	figure	NOUN
brainmatters-1084	43	4	1	1	NUM
brainmatters-1084	43	5	.	.	PUNCT
brainmatters-1084	44	1	estrogen	estrogen	NOUN
brainmatters-1084	44	2	and	and	CCONJ
brainmatters-1084	44	3	progesterone	progesterone	NOUN
brainmatters-1084	44	4	receptor	receptor	NOUN
brainmatters-1084	44	5	concentrations	concentration	NOUN
brainmatters-1084	44	6	throughout	throughout	ADP
brainmatters-1084	44	7	the	the	DET
brainmatters-1084	44	8	brain	brain	NOUN
brainmatters-1084	44	9	,	,	PUNCT
brainmatters-1084	44	10	displaying	display	VERB
brainmatters-1084	44	11	high	high	ADJ
brainmatters-1084	44	12	concentrations	concentration	NOUN
brainmatters-1084	44	13	in	in	ADP
brainmatters-1084	44	14	both	both	CCONJ
brainmatters-1084	44	15	the	the	DET
brainmatters-1084	44	16	hippocampal	hippocampal	ADJ
brainmatters-1084	44	17	and	and	CCONJ
brainmatters-1084	44	18	prefrontal	prefrontal	ADJ
brainmatters-1084	44	19	cortex	cortex	NOUN
brainmatters-1084	44	20	regions	region	NOUN
brainmatters-1084	44	21	(	(	PUNCT
brainmatters-1084	44	22	boyle	boyle	PROPN
brainmatters-1084	44	23	et	et	PROPN
brainmatters-1084	44	24	al	al	PROPN
brainmatters-1084	44	25	.	.	PROPN
brainmatters-1084	44	26	,	,	PUNCT
brainmatters-1084	44	27	2020	2020	NUM
brainmatters-1084	44	28	)	)	PUNCT
brainmatters-1084	44	29	function	function	NOUN
brainmatters-1084	44	30	,	,	PUNCT
brainmatters-1084	44	31	and	and	CCONJ
brainmatters-1084	44	32	aβ	aβ	ADP
brainmatters-1084	44	33	clearance	clearance	NOUN
brainmatters-1084	44	34	before	before	SCONJ
brainmatters-1084	44	35	age	age	NOUN
brainmatters-1084	44	36	-	-	PUNCT
brainmatters-1084	44	37	related	relate	VERB
brainmatters-1084	44	38	declines	decline	NOUN
brainmatters-1084	44	39	solidify	solidify	VERB
brainmatters-1084	44	40	(	(	PUNCT
brainmatters-1084	44	41	maki	maki	PROPN
brainmatters-1084	44	42	&	&	CCONJ
brainmatters-1084	44	43	henderson	henderson	PROPN
brainmatters-1084	44	44	,	,	PUNCT
brainmatters-1084	44	45	2020	2020	NUM
brainmatters-1084	44	46	;	;	PUNCT
brainmatters-1084	44	47	whitmer	whitmer	PROPN
brainmatters-1084	44	48	et	et	PROPN
brainmatters-1084	44	49	al	al	PROPN
brainmatters-1084	44	50	.	.	PROPN
brainmatters-1084	44	51	,	,	PUNCT
brainmatters-1084	44	52	2011	2011	NUM
brainmatters-1084	44	53	)	)	PUNCT
brainmatters-1084	44	54	.	.	PUNCT
brainmatters-1084	45	1	espeland	espeland	VERB
brainmatters-1084	45	2	et	et	PROPN
brainmatters-1084	45	3	al	al	PROPN
brainmatters-1084	45	4	.	.	PROPN
brainmatters-1084	46	1	(	(	PUNCT
brainmatters-1084	46	2	2015	2015	NUM
brainmatters-1084	46	3	)	)	PUNCT
brainmatters-1084	46	4	reported	report	VERB
brainmatters-1084	46	5	that	that	SCONJ
brainmatters-1084	46	6	women	woman	NOUN
brainmatters-1084	46	7	who	who	PRON
brainmatters-1084	46	8	began	begin	VERB
brainmatters-1084	46	9	ert	ert	NOUN
brainmatters-1084	46	10	during	during	ADP
brainmatters-1084	46	11	the	the	DET
brainmatters-1084	46	12	menopausal	menopausal	ADJ
brainmatters-1084	46	13	transition	transition	NOUN
brainmatters-1084	46	14	exhibited	exhibit	VERB
brainmatters-1084	46	15	better	well	ADJ
brainmatters-1084	46	16	cognitive	cognitive	ADJ
brainmatters-1084	46	17	outcomes	outcome	NOUN
brainmatters-1084	46	18	compared	compare	VERB
brainmatters-1084	46	19	to	to	ADP
brainmatters-1084	46	20	those	those	PRON
brainmatters-1084	46	21	who	who	PRON
brainmatters-1084	46	22	delayed	delay	VERB
brainmatters-1084	46	23	therapy	therapy	NOUN
brainmatters-1084	46	24	,	,	PUNCT
brainmatters-1084	46	25	underscoring	underscore	VERB
brainmatters-1084	46	26	the	the	DET
brainmatters-1084	46	27	importance	importance	NOUN
brainmatters-1084	46	28	of	of	ADP
brainmatters-1084	46	29	early	early	ADJ
brainmatters-1084	46	30	intervention	intervention	NOUN
brainmatters-1084	46	31	.	.	PUNCT
brainmatters-1084	47	1	conversely	conversely	ADV
brainmatters-1084	47	2	,	,	PUNCT
brainmatters-1084	47	3	delayed	delay	VERB
brainmatters-1084	47	4	ert	ert	NOUN
brainmatters-1084	47	5	beyond	beyond	ADP
brainmatters-1084	47	6	this	this	DET
brainmatters-1084	47	7	critical	critical	ADJ
brainmatters-1084	47	8	period	period	NOUN
brainmatters-1084	47	9	can	can	AUX
brainmatters-1084	47	10	have	have	VERB
brainmatters-1084	47	11	detrimental	detrimental	ADJ
brainmatters-1084	47	12	effects	effect	NOUN
brainmatters-1084	47	13	,	,	PUNCT
brainmatters-1084	47	14	potentially	potentially	ADV
brainmatters-1084	47	15	increasing	increase	VERB
brainmatters-1084	47	16	the	the	DET
brainmatters-1084	47	17	risk	risk	NOUN
brainmatters-1084	47	18	of	of	ADP
brainmatters-1084	47	19	cognitive	cognitive	ADJ
brainmatters-1084	47	20	decline	decline	NOUN
brainmatters-1084	47	21	.	.	PUNCT
brainmatters-1084	48	1	whitmer	whitmer	PROPN
brainmatters-1084	48	2	et	et	PROPN
brainmatters-1084	48	3	al	al	PROPN
brainmatters-1084	48	4	.	.	PROPN
brainmatters-1084	49	1	(	(	PUNCT
brainmatters-1084	49	2	2011	2011	NUM
brainmatters-1084	49	3	)	)	PUNCT
brainmatters-1084	49	4	found	find	VERB
brainmatters-1084	49	5	that	that	SCONJ
brainmatters-1084	49	6	late	late	ADJ
brainmatters-1084	49	7	initiation	initiation	NOUN
brainmatters-1084	49	8	of	of	ADP
brainmatters-1084	49	9	ert	ert	NOUN
brainmatters-1084	49	10	correlated	correlate	VERB
brainmatters-1084	49	11	with	with	ADP
brainmatters-1084	49	12	an	an	DET
brainmatters-1084	49	13	elevated	elevated	ADJ
brainmatters-1084	49	14	risk	risk	NOUN
brainmatters-1084	49	15	of	of	ADP
brainmatters-1084	49	16	dementia	dementia	NOUN
brainmatters-1084	49	17	,	,	PUNCT
brainmatters-1084	49	18	suggesting	suggest	VERB
brainmatters-1084	49	19	that	that	SCONJ
brainmatters-1084	49	20	the	the	DET
brainmatters-1084	49	21	aging	age	VERB
brainmatters-1084	49	22	brain	brain	NOUN
brainmatters-1084	49	23	,	,	PUNCT
brainmatters-1084	49	24	after	after	ADP
brainmatters-1084	49	25	prolonged	prolonged	ADJ
brainmatters-1084	49	26	estrogen	estrogen	NOUN
brainmatters-1084	49	27	deficiency	deficiency	NOUN
brainmatters-1084	49	28	,	,	PUNCT
brainmatters-1084	49	29	may	may	AUX
brainmatters-1084	49	30	become	become	VERB
brainmatters-1084	49	31	less	less	ADV
brainmatters-1084	49	32	responsive	responsive	ADJ
brainmatters-1084	49	33	to	to	ADP
brainmatters-1084	49	34	hormonal	hormonal	ADJ
brainmatters-1084	49	35	interventions	intervention	NOUN
brainmatters-1084	49	36	or	or	CCONJ
brainmatters-1084	49	37	even	even	ADV
brainmatters-1084	49	38	react	react	VERB
brainmatters-1084	49	39	adversely	adversely	ADV
brainmatters-1084	49	40	due	due	ADJ
brainmatters-1084	49	41	to	to	ADP
brainmatters-1084	49	42	disrupted	disrupt	VERB
brainmatters-1084	49	43	compensatory	compensatory	ADJ
brainmatters-1084	49	44	mechanisms	mechanism	NOUN
brainmatters-1084	49	45	developed	develop	VERB
brainmatters-1084	49	46	in	in	ADP
brainmatters-1084	49	47	response	response	NOUN
brainmatters-1084	49	48	to	to	ADP
brainmatters-1084	49	49	earlier	early	ADJ
brainmatters-1084	49	50	estrogen	estrogen	NOUN
brainmatters-1084	49	51	loss	loss	NOUN
brainmatters-1084	49	52	.	.	PUNCT
brainmatters-1084	50	1	the	the	DET
brainmatters-1084	50	2	critical	critical	ADJ
brainmatters-1084	50	3	window	window	NOUN
brainmatters-1084	50	4	for	for	ADP
brainmatters-1084	50	5	estrogen	estrogen	NOUN
brainmatters-1084	50	6	replacement	replacement	NOUN
brainmatters-1084	50	7	therapy	therapy	NOUN
brainmatters-1084	50	8	in	in	ADP
brainmatters-1084	50	9	menopausal	menopausal	ADJ
brainmatters-1084	50	10	women	woman	NOUN
brainmatters-1084	50	11	:	:	PUNCT
brainmatters-1084	50	12	exploring	explore	VERB
brainmatters-1084	50	13	the	the	DET
brainmatters-1084	50	14	neuroprotective	neuroprotective	ADJ
brainmatters-1084	50	15	effects	effect	NOUN
brainmatters-1084	50	16	of	of	ADP
brainmatters-1084	50	17	estrogen	estrogen	NOUN
brainmatters-1084	50	18	in	in	ADP
brainmatters-1084	50	19	reducing	reduce	VERB
brainmatters-1084	50	20	dementia	dementia	NOUN
brainmatters-1084	50	21	risk	risk	VERB
brainmatters-1084	50	22	13	13	NUM
brainmatters-1084	50	23	clinical	clinical	ADJ
brainmatters-1084	50	24	implications	implication	NOUN
brainmatters-1084	50	25	and	and	CCONJ
brainmatters-1084	50	26	future	future	ADJ
brainmatters-1084	50	27	research	research	NOUN
brainmatters-1084	50	28	directions	direction	NOUN
brainmatters-1084	50	29	the	the	DET
brainmatters-1084	50	30	critical	critical	ADJ
brainmatters-1084	50	31	window	window	NOUN
brainmatters-1084	50	32	hypothesis	hypothesis	NOUN
brainmatters-1084	50	33	carries	carry	VERB
brainmatters-1084	50	34	substantial	substantial	ADJ
brainmatters-1084	50	35	clinical	clinical	ADJ
brainmatters-1084	50	36	implications	implication	NOUN
brainmatters-1084	50	37	,	,	PUNCT
brainmatters-1084	50	38	advocating	advocate	VERB
brainmatters-1084	50	39	for	for	ADP
brainmatters-1084	50	40	personalized	personalized	ADJ
brainmatters-1084	50	41	ert	ert	NOUN
brainmatters-1084	50	42	timing	timing	NOUN
brainmatters-1084	50	43	based	base	VERB
brainmatters-1084	50	44	on	on	ADP
brainmatters-1084	50	45	individual	individual	ADJ
brainmatters-1084	50	46	health	health	NOUN
brainmatters-1084	50	47	profiles	profile	NOUN
brainmatters-1084	50	48	and	and	CCONJ
brainmatters-1084	50	49	menopausal	menopausal	ADJ
brainmatters-1084	50	50	timing	timing	NOUN
brainmatters-1084	50	51	.	.	PUNCT
brainmatters-1084	51	1	tailoring	tailor	VERB
brainmatters-1084	51	2	ert	ert	NOUN
brainmatters-1084	51	3	protocols	protocol	NOUN
brainmatters-1084	51	4	could	could	AUX
brainmatters-1084	51	5	maximize	maximize	VERB
brainmatters-1084	51	6	cognitive	cognitive	ADJ
brainmatters-1084	51	7	benefits	benefit	NOUN
brainmatters-1084	51	8	and	and	CCONJ
brainmatters-1084	51	9	minimize	minimize	VERB
brainmatters-1084	51	10	risks	risk	NOUN
brainmatters-1084	51	11	,	,	PUNCT
brainmatters-1084	51	12	particularly	particularly	ADV
brainmatters-1084	51	13	for	for	ADP
brainmatters-1084	51	14	women	woman	NOUN
brainmatters-1084	51	15	at	at	ADP
brainmatters-1084	51	16	high	high	ADJ
brainmatters-1084	51	17	risk	risk	NOUN
brainmatters-1084	51	18	of	of	ADP
brainmatters-1084	51	19	alzheimer	alzheimer	PROPN
brainmatters-1084	51	20	’s	’s	PART
brainmatters-1084	51	21	disease	disease	NOUN
brainmatters-1084	51	22	.	.	PUNCT
brainmatters-1084	52	1	emerging	emerge	VERB
brainmatters-1084	52	2	studies	study	NOUN
brainmatters-1084	52	3	on	on	ADP
brainmatters-1084	52	4	selective	selective	ADJ
brainmatters-1084	52	5	estrogen	estrogen	NOUN
brainmatters-1084	52	6	receptor	receptor	NOUN
brainmatters-1084	52	7	modulators	modulator	NOUN
brainmatters-1084	52	8	(	(	PUNCT
brainmatters-1084	52	9	serms	serm	NOUN
brainmatters-1084	52	10	)	)	PUNCT
brainmatters-1084	52	11	indicate	indicate	VERB
brainmatters-1084	52	12	potential	potential	ADJ
brainmatters-1084	52	13	alternatives	alternative	NOUN
brainmatters-1084	52	14	to	to	ADP
brainmatters-1084	52	15	traditional	traditional	ADJ
brainmatters-1084	52	16	hormone	hormone	NOUN
brainmatters-1084	52	17	therapy	therapy	NOUN
brainmatters-1084	52	18	,	,	PUNCT
brainmatters-1084	52	19	offering	offer	VERB
brainmatters-1084	52	20	neuroprotective	neuroprotective	ADJ
brainmatters-1084	52	21	benefits	benefit	NOUN
brainmatters-1084	52	22	without	without	ADP
brainmatters-1084	52	23	the	the	DET
brainmatters-1084	52	24	associated	associated	ADJ
brainmatters-1084	52	25	risks	risk	NOUN
brainmatters-1084	52	26	(	(	PUNCT
brainmatters-1084	52	27	shumaker	shumaker	PROPN
brainmatters-1084	52	28	et	et	PROPN
brainmatters-1084	52	29	al	al	PROPN
brainmatters-1084	52	30	.	.	PROPN
brainmatters-1084	52	31	,	,	PUNCT
brainmatters-1084	52	32	2003	2003	NUM
brainmatters-1084	52	33	)	)	PUNCT
brainmatters-1084	52	34	.	.	PUNCT
brainmatters-1084	53	1	serms	serm	NOUN
brainmatters-1084	53	2	,	,	PUNCT
brainmatters-1084	53	3	such	such	ADJ
brainmatters-1084	53	4	as	as	ADP
brainmatters-1084	53	5	bazedoxifene	bazedoxifene	NOUN
brainmatters-1084	53	6	and	and	CCONJ
brainmatters-1084	53	7	ospemifene	ospemifene	NOUN
brainmatters-1084	53	8	,	,	PUNCT
brainmatters-1084	53	9	may	may	AUX
brainmatters-1084	53	10	selectively	selectively	ADV
brainmatters-1084	53	11	target	target	VERB
brainmatters-1084	53	12	estrogen	estrogen	NOUN
brainmatters-1084	53	13	pathways	pathway	NOUN
brainmatters-1084	53	14	that	that	PRON
brainmatters-1084	53	15	promote	promote	VERB
brainmatters-1084	53	16	cognitive	cognitive	ADJ
brainmatters-1084	53	17	health	health	NOUN
brainmatters-1084	53	18	while	while	SCONJ
brainmatters-1084	53	19	minimizing	minimize	VERB
brainmatters-1084	53	20	the	the	DET
brainmatters-1084	53	21	risk	risk	NOUN
brainmatters-1084	53	22	of	of	ADP
brainmatters-1084	53	23	breast	breast	NOUN
brainmatters-1084	53	24	cancer	cancer	NOUN
brainmatters-1084	53	25	,	,	PUNCT
brainmatters-1084	53	26	a	a	DET
brainmatters-1084	53	27	significant	significant	ADJ
brainmatters-1084	53	28	concern	concern	NOUN
brainmatters-1084	53	29	with	with	ADP
brainmatters-1084	53	30	conventional	conventional	ADJ
brainmatters-1084	53	31	ert	ert	NOUN
brainmatters-1084	53	32	(	(	PUNCT
brainmatters-1084	53	33	huang	huang	PROPN
brainmatters-1084	53	34	et	et	PROPN
brainmatters-1084	53	35	al	al	PROPN
brainmatters-1084	53	36	.	.	PROPN
brainmatters-1084	53	37	,	,	PUNCT
brainmatters-1084	53	38	2017	2017	NUM
brainmatters-1084	53	39	)	)	PUNCT
brainmatters-1084	53	40	.	.	PUNCT
brainmatters-1084	54	1	future	future	ADJ
brainmatters-1084	54	2	research	research	NOUN
brainmatters-1084	54	3	should	should	AUX
brainmatters-1084	54	4	continue	continue	VERB
brainmatters-1084	54	5	to	to	PART
brainmatters-1084	54	6	refine	refine	VERB
brainmatters-1084	54	7	ert	ert	NOUN
brainmatters-1084	54	8	protocols	protocol	NOUN
brainmatters-1084	54	9	and	and	CCONJ
brainmatters-1084	54	10	investigate	investigate	VERB
brainmatters-1084	54	11	serms	serm	NOUN
brainmatters-1084	54	12	and	and	CCONJ
brainmatters-1084	54	13	other	other	ADJ
brainmatters-1084	54	14	compounds	compound	NOUN
brainmatters-1084	54	15	that	that	PRON
brainmatters-1084	54	16	modulate	modulate	VERB
brainmatters-1084	54	17	estrogenic	estrogenic	ADJ
brainmatters-1084	54	18	activity	activity	NOUN
brainmatters-1084	54	19	to	to	PART
brainmatters-1084	54	20	offer	offer	VERB
brainmatters-1084	54	21	targeted	target	VERB
brainmatters-1084	54	22	,	,	PUNCT
brainmatters-1084	54	23	effective	effective	ADJ
brainmatters-1084	54	24	options	option	NOUN
brainmatters-1084	54	25	for	for	ADP
brainmatters-1084	54	26	cognitive	cognitive	ADJ
brainmatters-1084	54	27	support	support	NOUN
brainmatters-1084	54	28	in	in	ADP
brainmatters-1084	54	29	postmenopausal	postmenopausal	ADJ
brainmatters-1084	54	30	women	woman	NOUN
brainmatters-1084	54	31	.	.	PUNCT
brainmatters-1084	55	1	additionally	additionally	ADV
brainmatters-1084	55	2	,	,	PUNCT
brainmatters-1084	55	3	studies	study	NOUN
brainmatters-1084	55	4	examining	examine	VERB
brainmatters-1084	55	5	the	the	DET
brainmatters-1084	55	6	interaction	interaction	NOUN
brainmatters-1084	55	7	between	between	ADP
brainmatters-1084	55	8	genetic	genetic	ADJ
brainmatters-1084	55	9	factors	factor	NOUN
brainmatters-1084	55	10	,	,	PUNCT
brainmatters-1084	55	11	such	such	ADJ
brainmatters-1084	55	12	as	as	ADP
brainmatters-1084	55	13	apoe	apoe	PROPN
brainmatters-1084	55	14	ε4	ε4	PROPN
brainmatters-1084	55	15	allele	allele	NOUN
brainmatters-1084	55	16	status	status	NOUN
brainmatters-1084	55	17	,	,	PUNCT
brainmatters-1084	55	18	and	and	CCONJ
brainmatters-1084	55	19	the	the	DET
brainmatters-1084	55	20	efficacy	efficacy	NOUN
brainmatters-1084	55	21	of	of	ADP
brainmatters-1084	55	22	ert	ert	NOUN
brainmatters-1084	55	23	may	may	AUX
brainmatters-1084	55	24	yield	yield	VERB
brainmatters-1084	55	25	valuable	valuable	ADJ
brainmatters-1084	55	26	insights	insight	NOUN
brainmatters-1084	55	27	into	into	ADP
brainmatters-1084	55	28	optimizing	optimize	VERB
brainmatters-1084	55	29	treatment	treatment	NOUN
brainmatters-1084	55	30	for	for	ADP
brainmatters-1084	55	31	diverse	diverse	ADJ
brainmatters-1084	55	32	populations	population	NOUN
brainmatters-1084	55	33	(	(	PUNCT
brainmatters-1084	55	34	vakhitov	vakhitov	PROPN
brainmatters-1084	55	35	et	et	PROPN
brainmatters-1084	55	36	al	al	PROPN
brainmatters-1084	55	37	.	.	PROPN
brainmatters-1084	55	38	,	,	PUNCT
brainmatters-1084	55	39	2023	2023	NUM
brainmatters-1084	55	40	)	)	PUNCT
brainmatters-1084	55	41	.	.	PUNCT
brainmatters-1084	56	1	figure	figure	NOUN
brainmatters-1084	56	2	2	2	NUM
brainmatters-1084	56	3	.	.	PUNCT
brainmatters-1084	56	4	synthesis	synthesis	NOUN
brainmatters-1084	56	5	of	of	ADP
brainmatters-1084	56	6	therapeutic	therapeutic	ADJ
brainmatters-1084	56	7	strategies	strategy	NOUN
brainmatters-1084	56	8	targeting	target	VERB
brainmatters-1084	56	9	estrogen	estrogen	NOUN
brainmatters-1084	56	10	in	in	ADP
brainmatters-1084	56	11	an	an	DET
brainmatters-1084	56	12	effort	effort	NOUN
brainmatters-1084	56	13	to	to	PART
brainmatters-1084	56	14	degrade	degrade	VERB
brainmatters-1084	56	15	accumulated	accumulate	VERB
brainmatters-1084	56	16	beta	beta	ADJ
brainmatters-1084	56	17	amyloid	amyloid	NOUN
brainmatters-1084	56	18	plaque	plaque	NOUN
brainmatters-1084	56	19	and	and	CCONJ
brainmatters-1084	56	20	prevent	prevent	VERB
brainmatters-1084	56	21	alzheimer	alzheimer	PROPN
brainmatters-1084	56	22	’s	’s	PART
brainmatters-1084	56	23	disease	disease	NOUN
brainmatters-1084	56	24	(	(	PUNCT
brainmatters-1084	56	25	mishra	mishra	PROPN
brainmatters-1084	56	26	et	et	PROPN
brainmatters-1084	56	27	al	al	PROPN
brainmatters-1084	56	28	.	.	PROPN
brainmatters-1084	56	29	,	,	PUNCT
brainmatters-1084	56	30	2023	2023	NUM
brainmatters-1084	56	31	)	)	PUNCT
brainmatters-1084	56	32	conclusion	conclusion	NOUN
brainmatters-1084	56	33	estrogen	estrogen	NOUN
brainmatters-1084	56	34	’s	’s	PART
brainmatters-1084	56	35	influence	influence	NOUN
brainmatters-1084	56	36	on	on	ADP
brainmatters-1084	56	37	brain	brain	NOUN
brainmatters-1084	56	38	health	health	NOUN
brainmatters-1084	56	39	is	be	AUX
brainmatters-1084	56	40	profound	profound	ADJ
brainmatters-1084	56	41	,	,	PUNCT
brainmatters-1084	56	42	encompassing	encompass	VERB
brainmatters-1084	56	43	mitochondrial	mitochondrial	ADJ
brainmatters-1084	56	44	support	support	NOUN
brainmatters-1084	56	45	,	,	PUNCT
brainmatters-1084	56	46	neurogenesis	neurogenesis	NOUN
brainmatters-1084	56	47	,	,	PUNCT
brainmatters-1084	56	48	synaptic	synaptic	ADJ
brainmatters-1084	56	49	plasticity	plasticity	NOUN
brainmatters-1084	56	50	,	,	PUNCT
brainmatters-1084	56	51	and	and	CCONJ
brainmatters-1084	56	52	the	the	DET
brainmatters-1084	56	53	reduction	reduction	NOUN
brainmatters-1084	56	54	of	of	ADP
brainmatters-1084	56	55	neurodegenerative	neurodegenerative	ADJ
brainmatters-1084	56	56	pathology	pathology	NOUN
brainmatters-1084	56	57	.	.	PUNCT
brainmatters-1084	57	1	the	the	DET
brainmatters-1084	57	2	timing	timing	NOUN
brainmatters-1084	57	3	of	of	ADP
brainmatters-1084	57	4	ert	ert	NOUN
brainmatters-1084	57	5	initiation	initiation	NOUN
brainmatters-1084	57	6	,	,	PUNCT
brainmatters-1084	57	7	as	as	SCONJ
brainmatters-1084	57	8	emphasized	emphasize	VERB
brainmatters-1084	57	9	by	by	ADP
brainmatters-1084	57	10	the	the	DET
brainmatters-1084	57	11	critical	critical	ADJ
brainmatters-1084	57	12	window	window	NOUN
brainmatters-1084	57	13	hypothesis	hypothesis	NOUN
brainmatters-1084	57	14	,	,	PUNCT
brainmatters-1084	57	15	is	be	AUX
brainmatters-1084	57	16	crucial	crucial	ADJ
brainmatters-1084	57	17	for	for	ADP
brainmatters-1084	57	18	achieving	achieve	VERB
brainmatters-1084	57	19	these	these	DET
brainmatters-1084	57	20	neuroprotective	neuroprotective	ADJ
brainmatters-1084	57	21	benefits	benefit	NOUN
brainmatters-1084	57	22	.	.	PUNCT
brainmatters-1084	58	1	early	early	ADJ
brainmatters-1084	58	2	intervention	intervention	NOUN
brainmatters-1084	58	3	,	,	PUNCT
brainmatters-1084	58	4	aligned	align	VERB
brainmatters-1084	58	5	with	with	ADP
brainmatters-1084	58	6	the	the	DET
brainmatters-1084	58	7	menopausal	menopausal	ADJ
brainmatters-1084	58	8	transition	transition	NOUN
brainmatters-1084	58	9	,	,	PUNCT
brainmatters-1084	58	10	coincides	coincide	VERB
brainmatters-1084	58	11	with	with	ADP
brainmatters-1084	58	12	estrogen	estrogen	NOUN
brainmatters-1084	58	13	’s	’s	PART
brainmatters-1084	58	14	mechanisms	mechanism	NOUN
brainmatters-1084	58	15	in	in	ADP
brainmatters-1084	58	16	preserving	preserve	VERB
brainmatters-1084	58	17	cognitive	cognitive	ADJ
brainmatters-1084	58	18	health	health	NOUN
brainmatters-1084	58	19	and	and	CCONJ
brainmatters-1084	58	20	lowering	lower	VERB
brainmatters-1084	58	21	dementia	dementia	NOUN
brainmatters-1084	58	22	risk	risk	NOUN
brainmatters-1084	58	23	.	.	PUNCT
brainmatters-1084	59	1	ongoing	ongoing	ADJ
brainmatters-1084	59	2	research	research	NOUN
brainmatters-1084	59	3	should	should	AUX
brainmatters-1084	59	4	aim	aim	VERB
brainmatters-1084	59	5	to	to	PART
brainmatters-1084	59	6	elucidate	elucidate	VERB
brainmatters-1084	59	7	the	the	DET
brainmatters-1084	59	8	complex	complex	ADJ
brainmatters-1084	59	9	interplay	interplay	NOUN
brainmatters-1084	59	10	of	of	ADP
brainmatters-1084	59	11	estrogen	estrogen	NOUN
brainmatters-1084	59	12	signaling	signaling	ADJ
brainmatters-1084	59	13	,	,	PUNCT
brainmatters-1084	59	14	neuroprotection	neuroprotection	NOUN
brainmatters-1084	59	15	,	,	PUNCT
brainmatters-1084	59	16	and	and	CCONJ
brainmatters-1084	59	17	timing	timing	NOUN
brainmatters-1084	59	18	to	to	PART
brainmatters-1084	59	19	enhance	enhance	VERB
brainmatters-1084	59	20	cognitive	cognitive	ADJ
brainmatters-1084	59	21	resilience	resilience	NOUN
brainmatters-1084	59	22	in	in	ADP
brainmatters-1084	59	23	aging	age	VERB
brainmatters-1084	59	24	women	woman	NOUN
brainmatters-1084	59	25	.	.	PUNCT
brainmatters-1084	60	1	references	reference	NOUN
brainmatters-1084	60	2	1	1	NUM
brainmatters-1084	60	3	.	.	PUNCT
brainmatters-1084	60	4	boyle	boyle	PROPN
brainmatters-1084	60	5	,	,	PUNCT
brainmatters-1084	60	6	christina	christina	PROPN
brainmatters-1084	60	7	&	&	CCONJ
brainmatters-1084	60	8	raji	raji	PROPN
brainmatters-1084	60	9	,	,	PUNCT
brainmatters-1084	60	10	cyrus	cyrus	PROPN
brainmatters-1084	60	11	&	&	CCONJ
brainmatters-1084	60	12	erickson	erickson	PROPN
brainmatters-1084	60	13	,	,	PUNCT
brainmatters-1084	60	14	kirk	kirk	PROPN
brainmatters-1084	60	15	&	&	CCONJ
brainmatters-1084	60	16	lopez	lopez	PROPN
brainmatters-1084	60	17	,	,	PUNCT
brainmatters-1084	60	18	oscar	oscar	PROPN
brainmatters-1084	60	19	&	&	CCONJ
brainmatters-1084	60	20	gach	gach	PROPN
brainmatters-1084	60	21	,	,	PUNCT
brainmatters-1084	60	22	h.	h.	PROPN
brainmatters-1084	60	23	&	&	CCONJ
brainmatters-1084	60	24	kuller	kuller	PROPN
brainmatters-1084	60	25	,	,	PUNCT
brainmatters-1084	60	26	lewis	lewis	PROPN
brainmatters-1084	60	27	&	&	CCONJ
brainmatters-1084	60	28	longstreth	longstreth	PROPN
brainmatters-1084	60	29	,	,	PUNCT
brainmatters-1084	60	30	william	william	PROPN
brainmatters-1084	60	31	&	&	CCONJ
brainmatters-1084	60	32	carmichael	carmichael	PROPN
brainmatters-1084	60	33	,	,	PUNCT
brainmatters-1084	60	34	owen	owen	PROPN
brainmatters-1084	60	35	&	&	CCONJ
brainmatters-1084	60	36	riedel	riedel	PROPN
brainmatters-1084	60	37	,	,	PUNCT
brainmatters-1084	60	38	brandalyn	brandalyn	NOUN
brainmatters-1084	60	39	&	&	CCONJ
brainmatters-1084	60	40	thompson	thompson	PROPN
brainmatters-1084	60	41	,	,	PUNCT
brainmatters-1084	60	42	paul	paul	PROPN
brainmatters-1084	60	43	.	.	PUNCT
brainmatters-1084	61	1	(	(	PUNCT
brainmatters-1084	61	2	2020	2020	NUM
brainmatters-1084	61	3	)	)	PUNCT
brainmatters-1084	61	4	.	.	PUNCT
brainmatters-1084	62	1	estrogen	estrogen	NOUN
brainmatters-1084	62	2	,	,	PUNCT
brainmatters-1084	62	3	brain	brain	NOUN
brainmatters-1084	62	4	structure	structure	NOUN
brainmatters-1084	62	5	,	,	PUNCT
brainmatters-1084	62	6	and	and	CCONJ
brainmatters-1084	62	7	cognition	cognition	NOUN
brainmatters-1084	62	8	in	in	ADP
brainmatters-1084	62	9	postmenopausal	postmenopausal	ADJ
brainmatters-1084	62	10	women	woman	NOUN
brainmatters-1084	62	11	.	.	PUNCT
brainmatters-1084	63	1	human	human	ADJ
brainmatters-1084	63	2	brain	brain	NOUN
brainmatters-1084	63	3	mapping	mapping	NOUN
brainmatters-1084	63	4	.	.	PUNCT
brainmatters-1084	64	1	42.10.1002	42.10.1002	X
brainmatters-1084	64	2	/	/	SYM
brainmatters-1084	64	3	hbm.25200	hbm.25200	NOUN
brainmatters-1084	64	4	.	.	NOUN
brainmatters-1084	65	1	2	2	NUM
brainmatters-1084	65	2	.	.	X
brainmatters-1084	65	3	brinton	brinton	PROPN
brainmatters-1084	65	4	,	,	PUNCT
brainmatters-1084	65	5	r.	r.	PROPN
brainmatters-1084	65	6	d.	d.	PROPN
brainmatters-1084	65	7	(	(	PUNCT
brainmatters-1084	65	8	2013	2013	NUM
brainmatters-1084	65	9	)	)	PUNCT
brainmatters-1084	65	10	.	.	PUNCT
brainmatters-1084	66	1	the	the	DET
brainmatters-1084	66	2	healthy	healthy	ADJ
brainmatters-1084	66	3	cell	cell	NOUN
brainmatters-1084	66	4	bias	bias	NOUN
brainmatters-1084	66	5	of	of	ADP
brainmatters-1084	66	6	estrogen	estrogen	NOUN
brainmatters-1084	66	7	action	action	NOUN
brainmatters-1084	66	8	:	:	PUNCT
brainmatters-1084	66	9	a	a	DET
brainmatters-1084	66	10	key	key	ADJ
brainmatters-1084	66	11	mechanism	mechanism	NOUN
brainmatters-1084	66	12	for	for	ADP
brainmatters-1084	66	13	the	the	DET
brainmatters-1084	66	14	neuroprotective	neuroprotective	ADJ
brainmatters-1084	66	15	effects	effect	NOUN
brainmatters-1084	66	16	of	of	ADP
brainmatters-1084	66	17	estrogen	estrogen	NOUN
brainmatters-1084	66	18	against	against	ADP
brainmatters-1084	66	19	alzheimer	alzheimer	PROPN
brainmatters-1084	66	20	's	's	PART
brainmatters-1084	66	21	disease	disease	NOUN
brainmatters-1084	66	22	.	.	PUNCT
brainmatters-1084	67	1	frontiers	frontier	NOUN
brainmatters-1084	67	2	in	in	ADP
brainmatters-1084	67	3	neuroendocrinology	neuroendocrinology	NOUN
brainmatters-1084	67	4	,	,	PUNCT
brainmatters-1084	67	5	34(1	34(1	NUM
brainmatters-1084	67	6	)	)	PUNCT
brainmatters-1084	67	7	,	,	PUNCT
brainmatters-1084	67	8	29	29	NUM
brainmatters-1084	67	9	-	-	SYM
brainmatters-1084	67	10	41	41	NUM
brainmatters-1084	67	11	.	.	PUNCT
brainmatters-1084	68	1	3	3	X
brainmatters-1084	68	2	.	.	X
brainmatters-1084	68	3	daniel	daniel	PROPN
brainmatters-1084	68	4	,	,	PUNCT
brainmatters-1084	68	5	j.	j.	PROPN
brainmatters-1084	68	6	m.	m.	PROPN
brainmatters-1084	68	7	,	,	PUNCT
brainmatters-1084	68	8	&	&	CCONJ
brainmatters-1084	68	9	dohanich	dohanich	NOUN
brainmatters-1084	68	10	,	,	PUNCT
brainmatters-1084	68	11	g.	g.	PROPN
brainmatters-1084	68	12	p.	p.	PROPN
brainmatters-1084	68	13	(	(	PUNCT
brainmatters-1084	68	14	2015	2015	NUM
brainmatters-1084	68	15	)	)	PUNCT
brainmatters-1084	68	16	.	.	PUNCT
brainmatters-1084	69	1	testosterone	testosterone	NOUN
brainmatters-1084	69	2	enhances	enhance	VERB
brainmatters-1084	69	3	spatial	spatial	ADJ
brainmatters-1084	69	4	and	and	CCONJ
brainmatters-1084	69	5	working	working	NOUN
brainmatters-1084	69	6	memory	memory	NOUN
brainmatters-1084	69	7	in	in	ADP
brainmatters-1084	69	8	male	male	ADJ
brainmatters-1084	69	9	rats	rat	NOUN
brainmatters-1084	69	10	.	.	PUNCT
brainmatters-1084	70	1	behavioral	behavioral	ADJ
brainmatters-1084	70	2	neuroscience	neuroscience	NOUN
brainmatters-1084	70	3	,	,	PUNCT
brainmatters-1084	70	4	119(1	119(1	NUM
brainmatters-1084	70	5	)	)	PUNCT
brainmatters-1084	70	6	,	,	PUNCT
brainmatters-1084	70	7	1	1	NUM
brainmatters-1084	70	8	-	-	SYM
brainmatters-1084	70	9	8	8	NUM
brainmatters-1084	70	10	.	.	NOUN
brainmatters-1084	70	11	4	4	X
brainmatters-1084	70	12	.	.	X
brainmatters-1084	71	1	espeland	espeland	NOUN
brainmatters-1084	71	2	,	,	PUNCT
brainmatters-1084	71	3	m.	m.	NOUN
brainmatters-1084	71	4	a.	a.	PROPN
brainmatters-1084	71	5	,	,	PUNCT
brainmatters-1084	71	6	shumaker	shumaker	PROPN
brainmatters-1084	71	7	,	,	PUNCT
brainmatters-1084	71	8	s.	s.	PROPN
brainmatters-1084	71	9	a.	a.	PROPN
brainmatters-1084	71	10	,	,	PUNCT
brainmatters-1084	71	11	leng	leng	PROPN
brainmatters-1084	71	12	,	,	PUNCT
brainmatters-1084	71	13	i.	i.	PROPN
brainmatters-1084	71	14	,	,	PUNCT
brainmatters-1084	71	15	et	et	PROPN
brainmatters-1084	71	16	al	al	PROPN
brainmatters-1084	71	17	.	.	PUNCT
brainmatters-1084	72	1	(	(	PUNCT
brainmatters-1084	72	2	2015	2015	NUM
brainmatters-1084	72	3	)	)	PUNCT
brainmatters-1084	72	4	.	.	PUNCT
brainmatters-1084	73	1	conjugated	conjugate	VERB
brainmatters-1084	73	2	equine	equine	NOUN
brainmatters-1084	73	3	estrogens	estrogen	NOUN
brainmatters-1084	73	4	and	and	CCONJ
brainmatters-1084	73	5	global	global	ADJ
brainmatters-1084	73	6	cognitive	cognitive	ADJ
brainmatters-1084	73	7	function	function	NOUN
brainmatters-1084	73	8	in	in	ADP
brainmatters-1084	73	9	postmenopausal	postmenopausal	ADJ
brainmatters-1084	73	10	women	woman	NOUN
brainmatters-1084	73	11	:	:	PUNCT
brainmatters-1084	73	12	a	a	DET
brainmatters-1084	73	13	randomized	randomized	ADJ
brainmatters-1084	73	14	trial	trial	NOUN
brainmatters-1084	73	15	.	.	PUNCT
brainmatters-1084	74	1	alzheimer	alzheimer	PROPN
brainmatters-1084	74	2	's	's	PART
brainmatters-1084	74	3	&	&	CCONJ
brainmatters-1084	74	4	dementia	dementia	PROPN
brainmatters-1084	74	5	,	,	PUNCT
brainmatters-1084	74	6	11(2	11(2	NOUN
brainmatters-1084	74	7	)	)	PUNCT
brainmatters-1084	74	8	,	,	PUNCT
brainmatters-1084	74	9	143	143	NUM
brainmatters-1084	74	10	-	-	SYM
brainmatters-1084	74	11	152	152	NUM
brainmatters-1084	74	12	.	.	PUNCT
brainmatters-1084	74	13	5	5	NUM
brainmatters-1084	74	14	.	.	X
brainmatters-1084	74	15	gibbs	gibbs	PROPN
brainmatters-1084	74	16	,	,	PUNCT
brainmatters-1084	74	17	r.	r.	PROPN
brainmatters-1084	74	18	b.	b.	PROPN
brainmatters-1084	74	19	,	,	PUNCT
brainmatters-1084	74	20	et	et	PROPN
brainmatters-1084	74	21	al	al	PROPN
brainmatters-1084	74	22	.	.	PUNCT
brainmatters-1084	74	23	(	(	PUNCT
brainmatters-1084	74	24	2000	2000	NUM
brainmatters-1084	74	25	)	)	PUNCT
brainmatters-1084	74	26	.	.	PUNCT
brainmatters-1084	75	1	estrogen	estrogen	NOUN
brainmatters-1084	75	2	replacement	replacement	NOUN
brainmatters-1084	75	3	in	in	ADP
brainmatters-1084	75	4	ovariectomized	ovariectomize	VERB
brainmatters-1084	75	5	rats	rat	NOUN
brainmatters-1084	75	6	:	:	PUNCT
brainmatters-1084	75	7	effects	effect	NOUN
brainmatters-1084	75	8	on	on	ADP
brainmatters-1084	75	9	neurogenesis	neurogenesis	NOUN
brainmatters-1084	75	10	and	and	CCONJ
brainmatters-1084	75	11	behavior	behavior	NOUN
brainmatters-1084	75	12	.	.	PUNCT
brainmatters-1084	76	1	journal	journal	PROPN
brainmatters-1084	76	2	of	of	ADP
brainmatters-1084	76	3	neurobiology	neurobiology	NOUN
brainmatters-1084	76	4	,	,	PUNCT
brainmatters-1084	76	5	56(1	56(1	NUM
brainmatters-1084	76	6	)	)	PUNCT
brainmatters-1084	76	7	,	,	PUNCT
brainmatters-1084	76	8	44	44	NUM
brainmatters-1084	76	9	-	-	SYM
brainmatters-1084	76	10	51	51	NUM
brainmatters-1084	76	11	.	.	PUNCT
brainmatters-1084	77	1	6	6	NUM
brainmatters-1084	77	2	.	.	X
brainmatters-1084	77	3	huang	huang	PROPN
brainmatters-1084	77	4	,	,	PUNCT
brainmatters-1084	77	5	y.	y.	PROPN
brainmatters-1084	77	6	,	,	PUNCT
brainmatters-1084	77	7	et	et	PROPN
brainmatters-1084	77	8	al	al	PROPN
brainmatters-1084	77	9	.	.	PUNCT
brainmatters-1084	77	10	(	(	PUNCT
brainmatters-1084	77	11	2017	2017	NUM
brainmatters-1084	77	12	)	)	PUNCT
brainmatters-1084	77	13	.	.	PUNCT
brainmatters-1084	78	1	selective	selective	ADJ
brainmatters-1084	78	2	estrogen	estrogen	NOUN
brainmatters-1084	78	3	receptor	receptor	NOUN
brainmatters-1084	78	4	modulators	modulator	NOUN
brainmatters-1084	78	5	:	:	PUNCT
brainmatters-1084	78	6	a	a	DET
brainmatters-1084	78	7	potential	potential	ADJ
brainmatters-1084	78	8	alternative	alternative	NOUN
brainmatters-1084	78	9	to	to	ADP
brainmatters-1084	78	10	estrogen	estrogen	NOUN
brainmatters-1084	78	11	therapy	therapy	NOUN
brainmatters-1084	78	12	for	for	ADP
brainmatters-1084	78	13	menopausal	menopausal	ADJ
brainmatters-1084	78	14	women	woman	NOUN
brainmatters-1084	78	15	.	.	PUNCT
brainmatters-1084	79	1	clinical	clinical	ADJ
brainmatters-1084	79	2	interventions	intervention	NOUN
brainmatters-1084	79	3	in	in	ADP
brainmatters-1084	79	4	aging	age	VERB
brainmatters-1084	79	5	,	,	PUNCT
brainmatters-1084	79	6	12	12	NUM
brainmatters-1084	79	7	,	,	PUNCT
brainmatters-1084	79	8	1517	1517	NUM
brainmatters-1084	79	9	-	-	SYM
brainmatters-1084	79	10	1525	1525	NUM
brainmatters-1084	79	11	.	.	PUNCT
brainmatters-1084	80	1	7	7	X
brainmatters-1084	80	2	.	.	X
brainmatters-1084	80	3	kuhlmann	kuhlmann	PROPN
brainmatters-1084	80	4	,	,	PUNCT
brainmatters-1084	80	5	a.	a.	NOUN
brainmatters-1084	80	6	m.	m.	NOUN
brainmatters-1084	80	7	,	,	PUNCT
brainmatters-1084	80	8	et	et	PROPN
brainmatters-1084	80	9	al	al	PROPN
brainmatters-1084	80	10	.	.	PROPN
brainmatters-1084	80	11	(	(	PUNCT
brainmatters-1084	80	12	2020	2020	NUM
brainmatters-1084	80	13	)	)	PUNCT
brainmatters-1084	80	14	.	.	PUNCT
brainmatters-1084	81	1	estrogen	estrogen	NOUN
brainmatters-1084	81	2	enhances	enhance	VERB
brainmatters-1084	81	3	microglial	microglial	ADJ
brainmatters-1084	81	4	-	-	PUNCT
brainmatters-1084	81	5	mediated	mediate	VERB
brainmatters-1084	81	6	clearance	clearance	NOUN
brainmatters-1084	81	7	of	of	ADP
brainmatters-1084	81	8	amyloid	amyloid	NOUN
brainmatters-1084	81	9	-	-	PUNCT
brainmatters-1084	81	10	beta	beta	NOUN
brainmatters-1084	81	11	in	in	ADP
brainmatters-1084	81	12	an	an	DET
brainmatters-1084	81	13	alzheimer	alzheimer	NOUN
brainmatters-1084	81	14	's	's	PART
brainmatters-1084	81	15	disease	disease	NOUN
brainmatters-1084	81	16	model	model	NOUN
brainmatters-1084	81	17	.	.	PUNCT
brainmatters-1084	82	1	journal	journal	PROPN
brainmatters-1084	82	2	of	of	ADP
brainmatters-1084	82	3	neuroinflammation	neuroinflammation	PROPN
brainmatters-1084	82	4	,	,	PUNCT
brainmatters-1084	82	5	17(1	17(1	NUM
brainmatters-1084	82	6	)	)	PUNCT
brainmatters-1084	82	7	,	,	PUNCT
brainmatters-1084	82	8	123	123	NUM
brainmatters-1084	82	9	.	.	PUNCT
brainmatters-1084	82	10	8	8	NUM
brainmatters-1084	82	11	.	.	X
brainmatters-1084	83	1	kumar	kumar	PROPN
brainmatters-1084	83	2	,	,	PUNCT
brainmatters-1084	83	3	a.	a.	PROPN
brainmatters-1084	83	4	,	,	PUNCT
brainmatters-1084	83	5	et	et	PROPN
brainmatters-1084	83	6	al	al	PROPN
brainmatters-1084	83	7	.	.	PROPN
brainmatters-1084	83	8	(	(	PUNCT
brainmatters-1084	83	9	2019	2019	NUM
brainmatters-1084	83	10	)	)	PUNCT
brainmatters-1084	83	11	.	.	PUNCT
brainmatters-1084	84	1	role	role	NOUN
brainmatters-1084	84	2	of	of	ADP
brainmatters-1084	84	3	estrogen	estrogen	NOUN
brainmatters-1084	84	4	in	in	ADP
brainmatters-1084	84	5	neuroprotection	neuroprotection	NOUN
brainmatters-1084	84	6	:	:	PUNCT
brainmatters-1084	84	7	the	the	DET
brainmatters-1084	84	8	present	present	NOUN
brainmatters-1084	84	9	and	and	CCONJ
brainmatters-1084	84	10	the	the	DET
brainmatters-1084	84	11	future	future	NOUN
brainmatters-1084	84	12	.	.	PUNCT
brainmatters-1084	85	1	current	current	ADJ
brainmatters-1084	85	2	neurovascular	neurovascular	ADJ
brainmatters-1084	85	3	research	research	NOUN
brainmatters-1084	85	4	,	,	PUNCT
brainmatters-1084	85	5	16(2	16(2	NUM
brainmatters-1084	85	6	)	)	PUNCT
brainmatters-1084	85	7	,	,	PUNCT
brainmatters-1084	85	8	158	158	NUM
brainmatters-1084	85	9	-	-	SYM
brainmatters-1084	85	10	166	166	NUM
brainmatters-1084	85	11	.	.	PUNCT
brainmatters-1084	86	1	9	9	NUM
brainmatters-1084	86	2	.	.	X
brainmatters-1084	87	1	liu	liu	PROPN
brainmatters-1084	87	2	,	,	PUNCT
brainmatters-1084	87	3	h.	h.	PROPN
brainmatters-1084	87	4	,	,	PUNCT
brainmatters-1084	87	5	et	et	PROPN
brainmatters-1084	87	6	al	al	PROPN
brainmatters-1084	87	7	.	.	PROPN
brainmatters-1084	87	8	(	(	PUNCT
brainmatters-1084	87	9	2019	2019	NUM
brainmatters-1084	87	10	)	)	PUNCT
brainmatters-1084	87	11	.	.	PUNCT
brainmatters-1084	88	1	estrogen	estrogen	NOUN
brainmatters-1084	88	2	treatment	treatment	NOUN
brainmatters-1084	88	3	improves	improve	VERB
brainmatters-1084	88	4	synaptic	synaptic	ADJ
brainmatters-1084	88	5	plasticity	plasticity	NOUN
brainmatters-1084	88	6	in	in	ADP
brainmatters-1084	88	7	aged	aged	ADJ
brainmatters-1084	88	8	ovariectomized	ovariectomize	VERB
brainmatters-1084	88	9	rats	rat	NOUN
brainmatters-1084	88	10	.	.	PUNCT
brainmatters-1084	89	1	neuroscience	neuroscience	NOUN
brainmatters-1084	89	2	letters	letter	NOUN
brainmatters-1084	89	3	,	,	PUNCT
brainmatters-1084	89	4	693	693	NUM
brainmatters-1084	89	5	,	,	PUNCT
brainmatters-1084	89	6	88	88	NUM
brainmatters-1084	89	7	-	-	SYM
brainmatters-1084	89	8	94	94	NUM
brainmatters-1084	89	9	.	.	PUNCT
brainmatters-1084	90	1	10	10	NUM
brainmatters-1084	90	2	.	.	PUNCT
brainmatters-1084	91	1	maki	maki	NOUN
brainmatters-1084	91	2	,	,	PUNCT
brainmatters-1084	91	3	p.	p.	NOUN
brainmatters-1084	91	4	m.	m.	NOUN
brainmatters-1084	91	5	,	,	PUNCT
brainmatters-1084	91	6	&	&	CCONJ
brainmatters-1084	91	7	henderson	henderson	PROPN
brainmatters-1084	91	8	,	,	PUNCT
brainmatters-1084	91	9	v.	v.	ADP
brainmatters-1084	91	10	w.	w.	PROPN
brainmatters-1084	91	11	(	(	PUNCT
brainmatters-1084	91	12	2020	2020	NUM
brainmatters-1084	91	13	)	)	PUNCT
brainmatters-1084	91	14	.	.	PUNCT
brainmatters-1084	92	1	hormone	hormone	NOUN
brainmatters-1084	92	2	therapy	therapy	NOUN
brainmatters-1084	92	3	in	in	ADP
brainmatters-1084	92	4	perimenopause	perimenopause	NOUN
brainmatters-1084	92	5	and	and	CCONJ
brainmatters-1084	92	6	menopause	menopause	NOUN
brainmatters-1084	92	7	:	:	PUNCT
brainmatters-1084	92	8	what	what	PRON
brainmatters-1084	92	9	are	be	AUX
brainmatters-1084	92	10	the	the	DET
brainmatters-1084	92	11	benefits	benefit	NOUN
brainmatters-1084	92	12	?	?	PUNCT
brainmatters-1084	93	1	journal	journal	NOUN
brainmatters-1084	93	2	of	of	ADP
brainmatters-1084	93	3	women	woman	NOUN
brainmatters-1084	93	4	’s	’s	PART
brainmatters-1084	93	5	health	health	NOUN
brainmatters-1084	93	6	,	,	PUNCT
brainmatters-1084	93	7	29(8	29(8	NOUN
brainmatters-1084	93	8	)	)	PUNCT
brainmatters-1084	93	9	,	,	PUNCT
brainmatters-1084	93	10	1031	1031	NUM
brainmatters-1084	93	11	-	-	SYM
brainmatters-1084	93	12	1038	1038	NUM
brainmatters-1084	93	13	.	.	PUNCT
brainmatters-1084	94	1	11	11	NUM
brainmatters-1084	94	2	.	.	X
brainmatters-1084	95	1	mishra	mishra	PROPN
brainmatters-1084	95	2	,	,	PUNCT
brainmatters-1084	95	3	p.	p.	PROPN
brainmatters-1084	95	4	,	,	PUNCT
brainmatters-1084	95	5	davies	davy	NOUN
brainmatters-1084	95	6	,	,	PUNCT
brainmatters-1084	95	7	d.	d.	PROPN
brainmatters-1084	95	8	a.	a.	PROPN
brainmatters-1084	95	9	,	,	PUNCT
brainmatters-1084	95	10	&	&	CCONJ
brainmatters-1084	95	11	albensi	albensi	PROPN
brainmatters-1084	95	12	,	,	PUNCT
brainmatters-1084	95	13	b.	b.	PROPN
brainmatters-1084	95	14	c.	c.	PROPN
brainmatters-1084	95	15	(	(	PUNCT
brainmatters-1084	95	16	2023	2023	NUM
brainmatters-1084	95	17	)	)	PUNCT
brainmatters-1084	95	18	.	.	PUNCT
brainmatters-1084	96	1	the	the	DET
brainmatters-1084	96	2	interaction	interaction	NOUN
brainmatters-1084	96	3	between	between	ADP
brainmatters-1084	96	4	nf	nf	NOUN
brainmatters-1084	96	5	-	-	PUNCT
brainmatters-1084	96	6	κb	κb	NOUN
brainmatters-1084	96	7	and	and	CCONJ
brainmatters-1084	96	8	estrogen	estrogen	NOUN
brainmatters-1084	96	9	in	in	ADP
brainmatters-1084	96	10	alzheimer	alzheimer	PROPN
brainmatters-1084	96	11	's	's	PART
brainmatters-1084	96	12	disease	disease	NOUN
brainmatters-1084	96	13	.	.	PUNCT
brainmatters-1084	97	1	molecular	molecular	ADJ
brainmatters-1084	97	2	neurobiology	neurobiology	NOUN
brainmatters-1084	97	3	,	,	PUNCT
brainmatters-1084	97	4	60	60	NUM
brainmatters-1084	97	5	,	,	PUNCT
brainmatters-1084	97	6	1515–1526	1515–1526	NUM
brainmatters-1084	97	7	.	.	PUNCT
brainmatters-1084	98	1	https://doi.org/10.1007/s12035-022-03152-3	https://doi.org/10.1007/s12035-022-03152-3	NUM
brainmatters-1084	98	2	12	12	NUM
brainmatters-1084	98	3	.	.	PUNCT
brainmatters-1084	99	1	mosconi	mosconi	PROPN
brainmatters-1084	99	2	,	,	PUNCT
brainmatters-1084	99	3	l.	l.	PROPN
brainmatters-1084	99	4	,	,	PUNCT
brainmatters-1084	99	5	et	et	PROPN
brainmatters-1084	99	6	al	al	PROPN
brainmatters-1084	99	7	.	.	PUNCT
brainmatters-1084	99	8	(	(	PUNCT
brainmatters-1084	99	9	2017	2017	NUM
brainmatters-1084	99	10	)	)	PUNCT
brainmatters-1084	99	11	.	.	PUNCT
brainmatters-1084	100	1	declining	decline	VERB
brainmatters-1084	100	2	estrogen	estrogen	NOUN
brainmatters-1084	100	3	levels	level	NOUN
brainmatters-1084	100	4	and	and	CCONJ
brainmatters-1084	100	5	alzheimer	alzheimer	PROPN
brainmatters-1084	100	6	's	's	PART
brainmatters-1084	100	7	disease	disease	NOUN
brainmatters-1084	100	8	:	:	PUNCT
brainmatters-1084	100	9	why	why	SCONJ
brainmatters-1084	100	10	the	the	DET
brainmatters-1084	100	11	first	first	ADJ
brainmatters-1084	100	12	10	10	NUM
brainmatters-1084	100	13	years	year	NOUN
brainmatters-1084	100	14	of	of	ADP
brainmatters-1084	100	15	menopause	menopause	NOUN
brainmatters-1084	100	16	matter	matter	NOUN
brainmatters-1084	100	17	.	.	PUNCT
brainmatters-1084	101	1	the	the	DET
brainmatters-1084	101	2	journal	journal	PROPN
brainmatters-1084	101	3	of	of	ADP
brainmatters-1084	101	4	alzheimer	alzheimer	PROPN
brainmatters-1084	101	5	's	's	PART
brainmatters-1084	101	6	disease	disease	NOUN
brainmatters-1084	101	7	,	,	PUNCT
brainmatters-1084	101	8	60(4	60(4	NUM
brainmatters-1084	101	9	)	)	PUNCT
brainmatters-1084	101	10	,	,	PUNCT
brainmatters-1084	101	11	1217	1217	NUM
brainmatters-1084	101	12	-	-	SYM
brainmatters-1084	101	13	1225	1225	NUM
brainmatters-1084	101	14	.	.	PUNCT
brainmatters-1084	102	1	13	13	NUM
brainmatters-1084	102	2	.	.	X
brainmatters-1084	102	3	shumaker	shumaker	PROPN
brainmatters-1084	102	4	,	,	PUNCT
brainmatters-1084	102	5	s.	s.	PROPN
brainmatters-1084	102	6	a.	a.	PROPN
brainmatters-1084	102	7	,	,	PUNCT
brainmatters-1084	102	8	et	et	PROPN
brainmatters-1084	102	9	al	al	PROPN
brainmatters-1084	102	10	.	.	PUNCT
brainmatters-1084	102	11	(	(	PUNCT
brainmatters-1084	102	12	2003	2003	NUM
brainmatters-1084	102	13	)	)	PUNCT
brainmatters-1084	102	14	.	.	PUNCT
brainmatters-1084	103	1	estrogen	estrogen	NOUN
brainmatters-1084	103	2	and	and	CCONJ
brainmatters-1084	103	3	progestin	progestin	NOUN
brainmatters-1084	103	4	use	use	NOUN
brainmatters-1084	103	5	and	and	CCONJ
brainmatters-1084	103	6	cognitive	cognitive	ADJ
brainmatters-1084	103	7	function	function	NOUN
brainmatters-1084	103	8	in	in	ADP
brainmatters-1084	103	9	postmenopausal	postmenopausal	ADJ
brainmatters-1084	103	10	women	woman	NOUN
brainmatters-1084	103	11	.	.	PUNCT
brainmatters-1084	104	1	journal	journal	PROPN
brainmatters-1084	104	2	of	of	ADP
brainmatters-1084	104	3	the	the	DET
brainmatters-1084	104	4	american	american	PROPN
brainmatters-1084	104	5	medical	medical	PROPN
brainmatters-1084	104	6	association	association	PROPN
brainmatters-1084	104	7	,	,	PUNCT
brainmatters-1084	104	8	289(20	289(20	NUM
brainmatters-1084	104	9	)	)	PUNCT
brainmatters-1084	104	10	,	,	PUNCT
brainmatters-1084	104	11	2663	2663	NUM
brainmatters-1084	104	12	-	-	SYM
brainmatters-1084	104	13	2672	2672	NUM
brainmatters-1084	104	14	.	.	PUNCT
brainmatters-1084	105	1	14	14	NUM
brainmatters-1084	105	2	.	.	PUNCT
brainmatters-1084	106	1	turek	turek	NOUN
brainmatters-1084	106	2	,	,	PUNCT
brainmatters-1084	106	3	a.	a.	PROPN
brainmatters-1084	106	4	d.	d.	PROPN
brainmatters-1084	106	5	,	,	PUNCT
brainmatters-1084	106	6	&	&	CCONJ
brainmatters-1084	106	7	gąsior	gąsior	PROPN
brainmatters-1084	106	8	,	,	PUNCT
brainmatters-1084	106	9	m.	m.	NOUN
brainmatters-1084	106	10	(	(	PUNCT
brainmatters-1084	106	11	2023	2023	NUM
brainmatters-1084	106	12	)	)	PUNCT
brainmatters-1084	106	13	.	.	PUNCT
brainmatters-1084	107	1	the	the	DET
brainmatters-1084	107	2	critical	critical	ADJ
brainmatters-1084	107	3	window	window	NOUN
brainmatters-1084	107	4	for	for	ADP
brainmatters-1084	107	5	estrogen	estrogen	NOUN
brainmatters-1084	107	6	replacement	replacement	NOUN
brainmatters-1084	107	7	therapy	therapy	NOUN
brainmatters-1084	107	8	in	in	ADP
brainmatters-1084	107	9	menopausal	menopausal	ADJ
brainmatters-1084	107	10	women	woman	NOUN
brainmatters-1084	107	11	:	:	PUNCT
brainmatters-1084	107	12	insights	insight	NOUN
brainmatters-1084	107	13	into	into	ADP
brainmatters-1084	107	14	neuroprotection	neuroprotection	NOUN
brainmatters-1084	107	15	and	and	CCONJ
brainmatters-1084	107	16	cognitive	cognitive	ADJ
brainmatters-1084	107	17	health	health	NOUN
brainmatters-1084	107	18	.	.	PUNCT
brainmatters-1084	108	1	current	current	ADJ
brainmatters-1084	108	2	opinion	opinion	NOUN
brainmatters-1084	108	3	in	in	ADP
brainmatters-1084	108	4	endocrinology	endocrinology	NOUN
brainmatters-1084	108	5	,	,	PUNCT
brainmatters-1084	108	6	diabetes	diabetes	NOUN
brainmatters-1084	108	7	and	and	CCONJ
brainmatters-1084	108	8	obesity	obesity	NOUN
brainmatters-1084	108	9	,	,	PUNCT
brainmatters-1084	108	10	30(6	30(6	NUM
brainmatters-1084	108	11	)	)	PUNCT
brainmatters-1084	108	12	,	,	PUNCT
brainmatters-1084	108	13	435442	435442	NUM
brainmatters-1084	108	14	.	.	PUNCT
brainmatters-1084	109	1	15	15	NUM
brainmatters-1084	109	2	.	.	PUNCT
brainmatters-1084	110	1	vakhitov	vakhitov	PROPN
brainmatters-1084	110	2	,	,	PUNCT
brainmatters-1084	110	3	a.	a.	PROPN
brainmatters-1084	110	4	,	,	PUNCT
brainmatters-1084	110	5	et	et	PROPN
brainmatters-1084	110	6	al	al	PROPN
brainmatters-1084	110	7	.	.	PROPN
brainmatters-1084	110	8	(	(	PUNCT
brainmatters-1084	110	9	2023	2023	NUM
brainmatters-1084	110	10	)	)	PUNCT
brainmatters-1084	110	11	.	.	PUNCT
brainmatters-1084	111	1	estrogen	estrogen	NOUN
brainmatters-1084	111	2	therapy	therapy	NOUN
brainmatters-1084	111	3	and	and	CCONJ
brainmatters-1084	111	4	alzheimer	alzheimer	PROPN
brainmatters-1084	111	5	's	's	PART
brainmatters-1084	111	6	disease	disease	NOUN
brainmatters-1084	111	7	:	:	PUNCT
brainmatters-1084	111	8	a	a	DET
brainmatters-1084	111	9	review	review	NOUN
brainmatters-1084	111	10	of	of	ADP
brainmatters-1084	111	11	the	the	DET
brainmatters-1084	111	12	evidence	evidence	NOUN
brainmatters-1084	111	13	for	for	ADP
brainmatters-1084	111	14	the	the	DET
brainmatters-1084	111	15	apoe	apoe	PROPN
brainmatters-1084	111	16	ε4	ε4	PROPN
brainmatters-1084	111	17	allele	allele	PROPN
brainmatters-1084	111	18	.	.	PUNCT
brainmatters-1084	112	1	alzheimer	alzheimer	PROPN
brainmatters-1084	112	2	's	's	PART
brainmatters-1084	112	3	research	research	PROPN
brainmatters-1084	112	4	&	&	CCONJ
brainmatters-1084	112	5	therapy	therapy	NOUN
brainmatters-1084	112	6	,	,	PUNCT
brainmatters-1084	112	7	15(1	15(1	NUM
brainmatters-1084	112	8	)	)	PUNCT
brainmatters-1084	112	9	,	,	PUNCT
brainmatters-1084	112	10	15	15	NUM
brainmatters-1084	112	11	.	.	NOUN
brainmatters-1084	112	12	16	16	NUM
brainmatters-1084	112	13	.	.	PUNCT
brainmatters-1084	113	1	wang	wang	PROPN
brainmatters-1084	113	2	,	,	PUNCT
brainmatters-1084	113	3	y.	y.	PROPN
brainmatters-1084	113	4	,	,	PUNCT
brainmatters-1084	113	5	et	et	PROPN
brainmatters-1084	113	6	al	al	PROPN
brainmatters-1084	113	7	.	.	PUNCT
brainmatters-1084	113	8	(	(	PUNCT
brainmatters-1084	113	9	2015	2015	NUM
brainmatters-1084	113	10	)	)	PUNCT
brainmatters-1084	113	11	.	.	PUNCT
brainmatters-1084	114	1	estrogen	estrogen	NOUN
brainmatters-1084	114	2	enhances	enhance	VERB
brainmatters-1084	114	3	the	the	DET
brainmatters-1084	114	4	ability	ability	NOUN
brainmatters-1084	114	5	of	of	ADP
brainmatters-1084	114	6	the	the	DET
brainmatters-1084	114	7	hippocampus	hippocampus	NOUN
brainmatters-1084	114	8	to	to	PART
brainmatters-1084	114	9	respond	respond	VERB
brainmatters-1084	114	10	to	to	ADP
brainmatters-1084	114	11	stress	stress	NOUN
brainmatters-1084	114	12	.	.	PUNCT
brainmatters-1084	115	1	endocrinology	endocrinology	NOUN
brainmatters-1084	115	2	,	,	PUNCT
brainmatters-1084	115	3	156(2	156(2	NUM
brainmatters-1084	115	4	)	)	PUNCT
brainmatters-1084	115	5	,	,	PUNCT
brainmatters-1084	115	6	610	610	NUM
brainmatters-1084	115	7	-	-	SYM
brainmatters-1084	115	8	620	620	NUM
brainmatters-1084	115	9	.	.	PUNCT
brainmatters-1084	115	10	17	17	NUM
brainmatters-1084	115	11	.	.	PUNCT
brainmatters-1084	116	1	whitmer	whitmer	PROPN
brainmatters-1084	116	2	,	,	PUNCT
brainmatters-1084	116	3	r.	r.	PROPN
brainmatters-1084	116	4	a.	a.	PROPN
brainmatters-1084	116	5	,	,	PUNCT
brainmatters-1084	116	6	et	et	PROPN
brainmatters-1084	116	7	al	al	PROPN
brainmatters-1084	116	8	.	.	PUNCT
brainmatters-1084	116	9	(	(	PUNCT
brainmatters-1084	116	10	2011	2011	NUM
brainmatters-1084	116	11	)	)	PUNCT
brainmatters-1084	116	12	.	.	PUNCT
brainmatters-1084	117	1	estrogen	estrogen	NOUN
brainmatters-1084	117	2	and	and	CCONJ
brainmatters-1084	117	3	the	the	DET
brainmatters-1084	117	4	risk	risk	NOUN
brainmatters-1084	117	5	of	of	ADP
brainmatters-1084	117	6	dementia	dementia	NOUN
brainmatters-1084	117	7	:	:	PUNCT
brainmatters-1084	117	8	the	the	DET
brainmatters-1084	117	9	critical	critical	ADJ
brainmatters-1084	117	10	window	window	NOUN
brainmatters-1084	117	11	hypothesis	hypothesis	NOUN
brainmatters-1084	117	12	.	.	PUNCT
brainmatters-1084	118	1	neurobiology	neurobiology	NOUN
brainmatters-1084	118	2	of	of	ADP
brainmatters-1084	118	3	aging	aging	NOUN
brainmatters-1084	118	4	,	,	PUNCT
brainmatters-1084	118	5	32(2	32(2	NUM
brainmatters-1084	118	6	)	)	PUNCT
brainmatters-1084	118	7	,	,	PUNCT
brainmatters-1084	118	8	227	227	NUM
brainmatters-1084	118	9	-	-	SYM
brainmatters-1084	118	10	239	239	NUM
brainmatters-1084	118	11	.	.	PUNCT
brainmatters-1084	118	12	18	18	NUM
brainmatters-1084	118	13	.	.	X
brainmatters-1084	119	1	zhou	zhou	PROPN
brainmatters-1084	119	2	,	,	PUNCT
brainmatters-1084	119	3	z.	z.	PROPN
brainmatters-1084	119	4	,	,	PUNCT
brainmatters-1084	119	5	et	et	PROPN
brainmatters-1084	119	6	al	al	PROPN
brainmatters-1084	119	7	.	.	PUNCT
brainmatters-1084	119	8	(	(	PUNCT
brainmatters-1084	119	9	2017	2017	NUM
brainmatters-1084	119	10	)	)	PUNCT
brainmatters-1084	119	11	.	.	PUNCT
brainmatters-1084	120	1	estrogen	estrogen	NOUN
brainmatters-1084	120	2	modulates	modulate	NOUN
brainmatters-1084	120	3	synaptic	synaptic	ADJ
brainmatters-1084	120	4	plasticity	plasticity	NOUN
brainmatters-1084	120	5	in	in	ADP
brainmatters-1084	120	6	the	the	DET
brainmatters-1084	120	7	hippocampus	hippocampus	NOUN
brainmatters-1084	120	8	:	:	PUNCT
brainmatters-1084	120	9	a	a	DET
brainmatters-1084	120	10	review	review	NOUN
brainmatters-1084	120	11	.	.	PUNCT
brainmatters-1084	121	1	hormones	hormone	NOUN
brainmatters-1084	121	2	and	and	CCONJ
brainmatters-1084	121	3	behavior	behavior	NOUN
brainmatters-1084	121	4	,	,	PUNCT
brainmatters-1084	121	5	86	86	NUM
brainmatters-1084	121	6	,	,	PUNCT
brainmatters-1084	121	7	105	105	NUM
brainmatters-1084	121	8	-	-	SYM
brainmatters-1084	121	9	113	113	NUM
brainmatters-1084	121	10	.	.	PUNCT
brainmatters-1084	122	1	about	about	ADP
brainmatters-1084	122	2	the	the	DET
brainmatters-1084	122	3	author	author	NOUN
brainmatters-1084	122	4	sylvia	sylvia	PROPN
brainmatters-1084	122	5	merz	merz	PROPN
brainmatters-1084	122	6	is	be	AUX
brainmatters-1084	122	7	a	a	DET
brainmatters-1084	122	8	junior	junior	ADJ
brainmatters-1084	122	9	majoring	majoring	NOUN
brainmatters-1084	122	10	in	in	ADP
brainmatters-1084	122	11	psychology	psychology	NOUN
brainmatters-1084	122	12	with	with	ADP
brainmatters-1084	122	13	a	a	DET
brainmatters-1084	122	14	concentration	concentration	NOUN
brainmatters-1084	122	15	in	in	ADP
brainmatters-1084	122	16	cognitive	cognitive	ADJ
brainmatters-1084	122	17	neuroscience	neuroscience	NOUN
brainmatters-1084	122	18	and	and	CCONJ
brainmatters-1084	122	19	minors	minor	NOUN
brainmatters-1084	122	20	in	in	ADP
brainmatters-1084	122	21	public	public	ADJ
brainmatters-1084	122	22	health	health	NOUN
brainmatters-1084	122	23	and	and	CCONJ
brainmatters-1084	122	24	statistics	statistic	NOUN
brainmatters-1084	122	25	.	.	PUNCT
brainmatters-1084	123	1	on	on	ADP
brainmatters-1084	123	2	campus	campus	NOUN
brainmatters-1084	123	3	,	,	PUNCT
brainmatters-1084	123	4	she	she	PRON
brainmatters-1084	123	5	is	be	AUX
brainmatters-1084	123	6	involved	involve	VERB
brainmatters-1084	123	7	as	as	ADP
brainmatters-1084	123	8	a	a	DET
brainmatters-1084	123	9	research	research	NOUN
brainmatters-1084	123	10	assistant	assistant	NOUN
brainmatters-1084	123	11	within	within	ADP
brainmatters-1084	123	12	the	the	DET
brainmatters-1084	123	13	laboratory	laboratory	NOUN
brainmatters-1084	123	14	for	for	ADP
brainmatters-1084	123	15	the	the	DET
brainmatters-1084	123	16	emotion	emotion	NOUN
brainmatters-1084	123	17	and	and	CCONJ
brainmatters-1084	123	18	stress	stress	NOUN
brainmatters-1084	123	19	assessment	assessment	NOUN
brainmatters-1084	123	20	,	,	PUNCT
brainmatters-1084	123	21	a	a	DET
brainmatters-1084	123	22	course	course	NOUN
brainmatters-1084	123	23	assistant	assistant	NOUN
brainmatters-1084	123	24	for	for	ADP
brainmatters-1084	123	25	stat	stat	PROPN
brainmatters-1084	123	26	212	212	NUM
brainmatters-1084	123	27	(	(	PUNCT
brainmatters-1084	123	28	biostatistics	biostatistic	NOUN
brainmatters-1084	123	29	)	)	PUNCT
brainmatters-1084	123	30	,	,	PUNCT
brainmatters-1084	123	31	and	and	CCONJ
brainmatters-1084	123	32	a	a	DET
brainmatters-1084	123	33	member	member	NOUN
brainmatters-1084	123	34	of	of	ADP
brainmatters-1084	123	35	girls	girl	NOUN
brainmatters-1084	123	36	next	next	ADP
brainmatters-1084	123	37	door	door	NOUN
brainmatters-1084	123	38	(	(	PUNCT
brainmatters-1084	123	39	an	an	DET
brainmatters-1084	123	40	a	a	PRON
brainmatters-1084	123	41	cappella	cappella	NOUN
brainmatters-1084	123	42	group	group	NOUN
brainmatters-1084	123	43	)	)	PUNCT
brainmatters-1084	123	44	.	.	PUNCT
brainmatters-1084	124	1	she	she	PRON
brainmatters-1084	124	2	also	also	ADV
brainmatters-1084	124	3	serves	serve	VERB
brainmatters-1084	124	4	as	as	ADP
brainmatters-1084	124	5	a	a	DET
brainmatters-1084	124	6	community	community	NOUN
brainmatters-1084	124	7	representative	representative	NOUN
brainmatters-1084	124	8	for	for	ADP
brainmatters-1084	124	9	the	the	DET
brainmatters-1084	124	10	alzheimer	alzheimer	PROPN
brainmatters-1084	124	11	’s	’s	PROPN
brainmatters-1084	124	12	association	association	NOUN
brainmatters-1084	124	13	,	,	PUNCT
brainmatters-1084	124	14	through	through	ADP
brainmatters-1084	124	15	which	which	PRON
brainmatters-1084	124	16	she	she	PRON
brainmatters-1084	124	17	has	have	AUX
brainmatters-1084	124	18	integrated	integrate	VERB
brainmatters-1084	124	19	her	her	PRON
brainmatters-1084	124	20	passion	passion	NOUN
brainmatters-1084	124	21	for	for	ADP
brainmatters-1084	124	22	global	global	ADJ
brainmatters-1084	124	23	health	health	NOUN
brainmatters-1084	124	24	and	and	CCONJ
brainmatters-1084	124	25	psychology	psychology	NOUN
brainmatters-1084	124	26	to	to	PART
brainmatters-1084	124	27	contribute	contribute	VERB
brainmatters-1084	124	28	to	to	ADP
brainmatters-1084	124	29	aging	age	VERB
brainmatters-1084	124	30	research	research	NOUN
brainmatters-1084	124	31	.	.	PUNCT
brainmatters-1084	125	1	in	in	ADP
brainmatters-1084	125	2	her	her	PRON
brainmatters-1084	125	3	free	free	ADJ
brainmatters-1084	125	4	time	time	NOUN
brainmatters-1084	125	5	,	,	PUNCT
brainmatters-1084	125	6	sylvia	sylvia	PROPN
brainmatters-1084	125	7	loves	love	VERB
brainmatters-1084	125	8	to	to	PART
brainmatters-1084	125	9	hike	hike	VERB
brainmatters-1084	125	10	,	,	PUNCT
brainmatters-1084	125	11	thrift	thrift	NOUN
brainmatters-1084	125	12	,	,	PUNCT
brainmatters-1084	125	13	and	and	CCONJ
brainmatters-1084	125	14	sew	sew	PROPN
brainmatters-1084	125	15	!	!	PUNCT
brainmatters-1084	126	1	brain	brain	NOUN
brainmatters-1084	126	2	matters	matter	NOUN
brainmatters-1084	126	3	vol	vol	NOUN
brainmatters-1084	126	4	.	.	PROPN
brainmatters-1084	126	5	8	8	NUM
brainmatters-1084	126	6	2025	2025	NUM
brainmatters-1084	126	7	14	14	NUM
brainmatters-1084	126	8	15	15	NUM