id	sid	tid	token	lemma	pos
brainmatters-688	1	1	therapeutic	therapeutic	ADJ
brainmatters-688	1	2	techniques	technique	NOUN
brainmatters-688	1	3	for	for	ADP
brainmatters-688	1	4	neural	neural	ADJ
brainmatters-688	1	5	regeneration	regeneration	NOUN
brainmatters-688	1	6	in	in	ADP
brainmatters-688	1	7	the	the	DET
brainmatters-688	1	8	central	central	ADJ
brainmatters-688	1	9	nervous	nervous	ADJ
brainmatters-688	1	10	system	system	NOUN
brainmatters-688	1	11	chloe	chloe	PROPN
brainmatters-688	1	12	kim	kim	PROPN
brainmatters-688	1	13	scientists	scientist	NOUN
brainmatters-688	1	14	have	have	AUX
brainmatters-688	1	15	studied	study	VERB
brainmatters-688	1	16	multiple	multiple	ADJ
brainmatters-688	1	17	approaches	approach	NOUN
brainmatters-688	1	18	that	that	PRON
brainmatters-688	1	19	have	have	AUX
brainmatters-688	1	20	been	be	AUX
brainmatters-688	1	21	thought	think	VERB
brainmatters-688	1	22	to	to	PART
brainmatters-688	1	23	enhance	enhance	VERB
brainmatters-688	1	24	neural	neural	ADJ
brainmatters-688	1	25	regeneration	regeneration	NOUN
brainmatters-688	1	26	.	.	PUNCT
brainmatters-688	2	1	these	these	DET
brainmatters-688	2	2	approaches	approach	NOUN
brainmatters-688	2	3	have	have	AUX
brainmatters-688	2	4	led	lead	VERB
brainmatters-688	2	5	to	to	ADP
brainmatters-688	2	6	the	the	DET
brainmatters-688	2	7	development	development	NOUN
brainmatters-688	2	8	of	of	ADP
brainmatters-688	2	9	groundbreaking	groundbreake	VERB
brainmatters-688	2	10	treatment	treatment	NOUN
brainmatters-688	2	11	for	for	ADP
brainmatters-688	2	12	age	age	NOUN
brainmatters-688	2	13	-	-	PUNCT
brainmatters-688	2	14	related	relate	VERB
brainmatters-688	2	15	diseases	disease	NOUN
brainmatters-688	2	16	and	and	CCONJ
brainmatters-688	2	17	nerve	nerve	NOUN
brainmatters-688	2	18	injuries	injury	NOUN
brainmatters-688	2	19	.	.	PUNCT
brainmatters-688	3	1	the	the	DET
brainmatters-688	3	2	development	development	NOUN
brainmatters-688	3	3	and	and	CCONJ
brainmatters-688	3	4	use	use	NOUN
brainmatters-688	3	5	of	of	ADP
brainmatters-688	3	6	these	these	DET
brainmatters-688	3	7	treatments	treatment	NOUN
brainmatters-688	3	8	are	be	AUX
brainmatters-688	3	9	vital	vital	ADJ
brainmatters-688	3	10	because	because	SCONJ
brainmatters-688	3	11	spinal	spinal	ADJ
brainmatters-688	3	12	cord	cord	NOUN
brainmatters-688	3	13	injuries	injury	NOUN
brainmatters-688	3	14	and	and	CCONJ
brainmatters-688	3	15	traumatic	traumatic	ADJ
brainmatters-688	3	16	brain	brain	NOUN
brainmatters-688	3	17	injuries	injury	NOUN
brainmatters-688	3	18	alone	alone	ADV
brainmatters-688	3	19	affect	affect	VERB
brainmatters-688	3	20	90,000	90,000	NUM
brainmatters-688	3	21	people	people	NOUN
brainmatters-688	3	22	every	every	DET
brainmatters-688	3	23	year	year	NOUN
brainmatters-688	3	24	;	;	PUNCT
brainmatters-688	3	25	approximately	approximately	ADV
brainmatters-688	3	26	10,000	10,000	NUM
brainmatters-688	3	27	mostly	mostly	ADV
brainmatters-688	3	28	young	young	ADJ
brainmatters-688	3	29	individuals	individual	NOUN
brainmatters-688	3	30	are	be	AUX
brainmatters-688	3	31	affected	affect	VERB
brainmatters-688	3	32	by	by	ADP
brainmatters-688	3	33	acute	acute	ADJ
brainmatters-688	3	34	spinal	spinal	PROPN
brainmatters-688	3	35	cord	cord	NOUN
brainmatters-688	3	36	injury	injury	NOUN
brainmatters-688	3	37	and	and	CCONJ
brainmatters-688	3	38	50,000	50,000	NUM
brainmatters-688	3	39	die	die	NOUN
brainmatters-688	3	40	from	from	ADP
brainmatters-688	3	41	traumatic	traumatic	ADJ
brainmatters-688	3	42	brain	brain	NOUN
brainmatters-688	3	43	injury	injury	NOUN
brainmatters-688	3	44	each	each	DET
brainmatters-688	3	45	year	year	NOUN
brainmatters-688	3	46	(	(	PUNCT
brainmatters-688	3	47	stabenfeldt	stabenfeldt	NOUN
brainmatters-688	3	48	et	et	PROPN
brainmatters-688	3	49	al	al	PROPN
brainmatters-688	3	50	.	.	PROPN
brainmatters-688	3	51	,	,	PUNCT
brainmatters-688	3	52	2006	2006	NUM
brainmatters-688	3	53	)	)	PUNCT
brainmatters-688	3	54	.	.	PUNCT
brainmatters-688	4	1	it	it	PRON
brainmatters-688	4	2	is	be	AUX
brainmatters-688	4	3	also	also	ADV
brainmatters-688	4	4	important	important	ADJ
brainmatters-688	4	5	to	to	PART
brainmatters-688	4	6	note	note	VERB
brainmatters-688	4	7	that	that	SCONJ
brainmatters-688	4	8	neurodegenerative	neurodegenerative	ADJ
brainmatters-688	4	9	diseases	disease	NOUN
brainmatters-688	4	10	,	,	PUNCT
brainmatters-688	4	11	such	such	ADJ
brainmatters-688	4	12	as	as	ADP
brainmatters-688	4	13	alzheimer	alzheimer	PROPN
brainmatters-688	4	14	’s	’s	PART
brainmatters-688	4	15	or	or	CCONJ
brainmatters-688	4	16	parkinson	parkinson	NOUN
brainmatters-688	4	17	’s	’s	PART
brainmatters-688	4	18	disease	disease	NOUN
brainmatters-688	4	19	,	,	PUNCT
brainmatters-688	4	20	are	be	AUX
brainmatters-688	4	21	affecting	affect	VERB
brainmatters-688	4	22	a	a	DET
brainmatters-688	4	23	large	large	ADJ
brainmatters-688	4	24	portion	portion	NOUN
brainmatters-688	4	25	of	of	ADP
brainmatters-688	4	26	the	the	DET
brainmatters-688	4	27	aged	aged	ADJ
brainmatters-688	4	28	population	population	NOUN
brainmatters-688	4	29	worldwide	worldwide	ADV
brainmatters-688	4	30	.	.	PUNCT
brainmatters-688	5	1	as	as	SCONJ
brainmatters-688	5	2	the	the	DET
brainmatters-688	5	3	average	average	ADJ
brainmatters-688	5	4	human	human	ADJ
brainmatters-688	5	5	lifespan	lifespan	NOUN
brainmatters-688	5	6	is	be	AUX
brainmatters-688	5	7	expected	expect	VERB
brainmatters-688	5	8	to	to	PART
brainmatters-688	5	9	increase	increase	VERB
brainmatters-688	5	10	over	over	ADP
brainmatters-688	5	11	time	time	NOUN
brainmatters-688	5	12	,	,	PUNCT
brainmatters-688	5	13	the	the	DET
brainmatters-688	5	14	number	number	NOUN
brainmatters-688	5	15	of	of	ADP
brainmatters-688	5	16	people	people	NOUN
brainmatters-688	5	17	within	within	ADP
brainmatters-688	5	18	the	the	DET
brainmatters-688	5	19	population	population	NOUN
brainmatters-688	5	20	affected	affect	VERB
brainmatters-688	5	21	by	by	ADP
brainmatters-688	5	22	such	such	ADJ
brainmatters-688	5	23	diseases	disease	NOUN
brainmatters-688	5	24	is	be	AUX
brainmatters-688	5	25	projected	project	VERB
brainmatters-688	5	26	to	to	PART
brainmatters-688	5	27	grow	grow	VERB
brainmatters-688	5	28	by	by	ADP
brainmatters-688	5	29	mid	mid	ADJ
brainmatters-688	5	30	-	-	NOUN
brainmatters-688	5	31	century	century	NOUN
brainmatters-688	5	32	(	(	PUNCT
brainmatters-688	5	33	alzheimer	alzheimer	PROPN
brainmatters-688	5	34	's	's	PART
brainmatters-688	5	35	association	association	NOUN
brainmatters-688	5	36	,	,	PUNCT
brainmatters-688	5	37	2016	2016	NUM
brainmatters-688	5	38	)	)	PUNCT
brainmatters-688	5	39	.	.	PUNCT
brainmatters-688	6	1	thus	thus	ADV
brainmatters-688	6	2	,	,	PUNCT
brainmatters-688	6	3	by	by	ADP
brainmatters-688	6	4	recovering	recover	VERB
brainmatters-688	6	5	nerve	nerve	NOUN
brainmatters-688	6	6	functionality	functionality	NOUN
brainmatters-688	6	7	after	after	ADP
brainmatters-688	6	8	injury	injury	NOUN
brainmatters-688	6	9	,	,	PUNCT
brainmatters-688	6	10	nerve	nerve	NOUN
brainmatters-688	6	11	regeneration	regeneration	NOUN
brainmatters-688	6	12	techniques	technique	NOUN
brainmatters-688	6	13	have	have	VERB
brainmatters-688	6	14	great	great	ADJ
brainmatters-688	6	15	potential	potential	NOUN
brainmatters-688	6	16	to	to	PART
brainmatters-688	6	17	conquer	conquer	VERB
brainmatters-688	6	18	the	the	DET
brainmatters-688	6	19	problems	problem	NOUN
brainmatters-688	6	20	that	that	PRON
brainmatters-688	6	21	are	be	AUX
brainmatters-688	6	22	projected	project	VERB
brainmatters-688	6	23	to	to	PART
brainmatters-688	6	24	affect	affect	VERB
brainmatters-688	6	25	a	a	DET
brainmatters-688	6	26	significant	significant	ADJ
brainmatters-688	6	27	amount	amount	NOUN
brainmatters-688	6	28	of	of	ADP
brainmatters-688	6	29	the	the	DET
brainmatters-688	6	30	general	general	ADJ
brainmatters-688	6	31	population	population	NOUN
brainmatters-688	6	32	.	.	PUNCT
brainmatters-688	7	1	therefore	therefore	ADV
brainmatters-688	7	2	,	,	PUNCT
brainmatters-688	7	3	techniques	technique	NOUN
brainmatters-688	7	4	such	such	ADJ
brainmatters-688	7	5	as	as	ADP
brainmatters-688	7	6	neural	neural	ADJ
brainmatters-688	7	7	tissue	tissue	NOUN
brainmatters-688	7	8	engineering	engineering	NOUN
brainmatters-688	7	9	is	be	AUX
brainmatters-688	7	10	a	a	DET
brainmatters-688	7	11	rapidly	rapidly	ADV
brainmatters-688	7	12	growing	grow	VERB
brainmatters-688	7	13	field	field	NOUN
brainmatters-688	7	14	of	of	ADP
brainmatters-688	7	15	research	research	NOUN
brainmatters-688	7	16	that	that	PRON
brainmatters-688	7	17	has	have	VERB
brainmatters-688	7	18	the	the	DET
brainmatters-688	7	19	potential	potential	NOUN
brainmatters-688	7	20	to	to	PART
brainmatters-688	7	21	achieve	achieve	VERB
brainmatters-688	7	22	efficient	efficient	ADJ
brainmatters-688	7	23	nerve	nerve	NOUN
brainmatters-688	7	24	regeneration	regeneration	NOUN
brainmatters-688	7	25	.	.	PUNCT
brainmatters-688	8	1	nevertheless	nevertheless	ADV
brainmatters-688	8	2	,	,	PUNCT
brainmatters-688	8	3	most	most	ADJ
brainmatters-688	8	4	clinical	clinical	ADJ
brainmatters-688	8	5	treatments	treatment	NOUN
brainmatters-688	8	6	are	be	AUX
brainmatters-688	8	7	limited	limit	VERB
brainmatters-688	8	8	to	to	ADP
brainmatters-688	8	9	symptomatic	symptomatic	ADJ
brainmatters-688	8	10	methods	method	NOUN
brainmatters-688	8	11	,	,	PUNCT
brainmatters-688	8	12	as	as	SCONJ
brainmatters-688	8	13	in	in	ADP
brainmatters-688	8	14	vivo	vivo	ADJ
brainmatters-688	8	15	approaches	approach	NOUN
brainmatters-688	8	16	in	in	ADP
brainmatters-688	8	17	neural	neural	ADJ
brainmatters-688	8	18	regeneration	regeneration	NOUN
brainmatters-688	8	19	are	be	AUX
brainmatters-688	8	20	yet	yet	ADV
brainmatters-688	8	21	to	to	PART
brainmatters-688	8	22	be	be	AUX
brainmatters-688	8	23	utilized	utilize	VERB
brainmatters-688	8	24	.	.	PUNCT
brainmatters-688	9	1	in	in	ADP
brainmatters-688	9	2	this	this	DET
brainmatters-688	9	3	article	article	NOUN
brainmatters-688	9	4	,	,	PUNCT
brainmatters-688	9	5	current	current	ADJ
brainmatters-688	9	6	limitations	limitation	NOUN
brainmatters-688	9	7	and	and	CCONJ
brainmatters-688	9	8	newly	newly	ADV
brainmatters-688	9	9	developed	develop	VERB
brainmatters-688	9	10	methods	method	NOUN
brainmatters-688	9	11	of	of	ADP
brainmatters-688	9	12	neural	neural	ADJ
brainmatters-688	9	13	regeneration	regeneration	NOUN
brainmatters-688	9	14	are	be	AUX
brainmatters-688	9	15	to	to	PART
brainmatters-688	9	16	be	be	AUX
brainmatters-688	9	17	introduced	introduce	VERB
brainmatters-688	9	18	,	,	PUNCT
brainmatters-688	9	19	as	as	ADV
brainmatters-688	9	20	well	well	ADV
brainmatters-688	9	21	as	as	ADP
brainmatters-688	9	22	suggestions	suggestion	NOUN
brainmatters-688	9	23	on	on	ADP
brainmatters-688	9	24	possible	possible	ADJ
brainmatters-688	9	25	future	future	ADJ
brainmatters-688	9	26	improvements	improvement	NOUN
brainmatters-688	9	27	for	for	ADP
brainmatters-688	9	28	clinical	clinical	ADJ
brainmatters-688	9	29	adaptations	adaptation	NOUN
brainmatters-688	9	30	.	.	PUNCT
brainmatters-688	10	1	one	one	NUM
brainmatters-688	10	2	of	of	ADP
brainmatters-688	10	3	the	the	DET
brainmatters-688	10	4	greatest	great	ADJ
brainmatters-688	10	5	problems	problem	NOUN
brainmatters-688	10	6	in	in	ADP
brainmatters-688	10	7	neural	neural	ADJ
brainmatters-688	10	8	injuries	injury	NOUN
brainmatters-688	10	9	is	be	AUX
brainmatters-688	10	10	that	that	SCONJ
brainmatters-688	10	11	,	,	PUNCT
brainmatters-688	10	12	in	in	ADP
brainmatters-688	10	13	contrast	contrast	NOUN
brainmatters-688	10	14	to	to	ADP
brainmatters-688	10	15	the	the	DET
brainmatters-688	10	16	peripheral	peripheral	ADJ
brainmatters-688	10	17	nervous	nervous	ADJ
brainmatters-688	10	18	system	system	NOUN
brainmatters-688	10	19	,	,	PUNCT
brainmatters-688	10	20	the	the	DET
brainmatters-688	10	21	central	central	ADJ
brainmatters-688	10	22	nervous	nervous	ADJ
brainmatters-688	10	23	system	system	NOUN
brainmatters-688	10	24	(	(	PUNCT
brainmatters-688	10	25	cns	cns	NOUN
brainmatters-688	10	26	)	)	PUNCT
brainmatters-688	10	27	is	be	AUX
brainmatters-688	10	28	generally	generally	ADV
brainmatters-688	10	29	incapable	incapable	ADJ
brainmatters-688	10	30	of	of	ADP
brainmatters-688	10	31	self	self	NOUN
brainmatters-688	10	32	-	-	PUNCT
brainmatters-688	10	33	repair	repair	NOUN
brainmatters-688	10	34	or	or	CCONJ
brainmatters-688	10	35	regeneration	regeneration	NOUN
brainmatters-688	10	36	.	.	PUNCT
brainmatters-688	11	1	spontaneous	spontaneous	ADJ
brainmatters-688	11	2	regeneration	regeneration	NOUN
brainmatters-688	11	3	of	of	ADP
brainmatters-688	11	4	the	the	DET
brainmatters-688	11	5	cns	cns	NOUN
brainmatters-688	11	6	is	be	AUX
brainmatters-688	11	7	mainly	mainly	ADV
brainmatters-688	11	8	due	due	ADJ
brainmatters-688	11	9	to	to	ADP
brainmatters-688	11	10	functions	function	NOUN
brainmatters-688	11	11	of	of	ADP
brainmatters-688	11	12	inhibitory	inhibitory	ADJ
brainmatters-688	11	13	factors	factor	NOUN
brainmatters-688	11	14	,	,	PUNCT
brainmatters-688	11	15	and	and	CCONJ
brainmatters-688	11	16	little	little	ADJ
brainmatters-688	11	17	is	be	AUX
brainmatters-688	11	18	uncovered	uncover	VERB
brainmatters-688	11	19	about	about	ADP
brainmatters-688	11	20	this	this	DET
brainmatters-688	11	21	mechanism	mechanism	NOUN
brainmatters-688	11	22	of	of	ADP
brainmatters-688	11	23	inhibition	inhibition	NOUN
brainmatters-688	11	24	.	.	PUNCT
brainmatters-688	12	1	yet	yet	ADV
brainmatters-688	12	2	in	in	ADP
brainmatters-688	12	3	the	the	DET
brainmatters-688	12	4	late	late	ADJ
brainmatters-688	12	5	twentieth	twentieth	ADJ
brainmatters-688	12	6	century	century	NOUN
brainmatters-688	12	7	,	,	PUNCT
brainmatters-688	12	8	an	an	DET
brainmatters-688	12	9	explanation	explanation	NOUN
brainmatters-688	12	10	for	for	ADP
brainmatters-688	12	11	the	the	DET
brainmatters-688	12	12	functional	functional	ADJ
brainmatters-688	12	13	recovery	recovery	NOUN
brainmatters-688	12	14	of	of	ADP
brainmatters-688	12	15	the	the	DET
brainmatters-688	12	16	cns	cns	NOUN
brainmatters-688	12	17	was	be	AUX
brainmatters-688	12	18	introduced	introduce	VERB
brainmatters-688	12	19	based	base	VERB
brainmatters-688	12	20	on	on	ADP
brainmatters-688	12	21	the	the	DET
brainmatters-688	12	22	concept	concept	NOUN
brainmatters-688	12	23	of	of	ADP
brainmatters-688	12	24	neuroplasticity	neuroplasticity	NOUN
brainmatters-688	12	25	,	,	PUNCT
brainmatters-688	12	26	the	the	DET
brainmatters-688	12	27	cns	cns	NOUN
brainmatters-688	12	28	’s	’s	PART
brainmatters-688	12	29	ability	ability	NOUN
brainmatters-688	12	30	to	to	PART
brainmatters-688	12	31	anatomically	anatomically	ADV
brainmatters-688	12	32	and	and	CCONJ
brainmatters-688	12	33	functionally	functionally	ADV
brainmatters-688	12	34	adapt	adapt	VERB
brainmatters-688	12	35	to	to	ADP
brainmatters-688	12	36	changes	change	NOUN
brainmatters-688	12	37	.	.	PUNCT
brainmatters-688	13	1	in	in	ADP
brainmatters-688	13	2	addition	addition	NOUN
brainmatters-688	13	3	,	,	PUNCT
brainmatters-688	13	4	the	the	DET
brainmatters-688	13	5	concept	concept	NOUN
brainmatters-688	13	6	of	of	ADP
brainmatters-688	13	7	reactive	reactive	ADJ
brainmatters-688	13	8	synaptogenesis	synaptogenesis	NOUN
brainmatters-688	13	9	was	be	AUX
brainmatters-688	13	10	also	also	ADV
brainmatters-688	13	11	proposed	propose	VERB
brainmatters-688	13	12	in	in	ADP
brainmatters-688	13	13	1979	1979	NUM
brainmatters-688	13	14	.	.	PUNCT
brainmatters-688	14	1	reactive	reactive	ADJ
brainmatters-688	14	2	synaptogenesis	synaptogenesis	NOUN
brainmatters-688	14	3	is	be	AUX
brainmatters-688	14	4	the	the	DET
brainmatters-688	14	5	process	process	NOUN
brainmatters-688	14	6	in	in	ADP
brainmatters-688	14	7	which	which	PRON
brainmatters-688	14	8	neighboring	neighboring	NOUN
brainmatters-688	14	9	neurons	neuron	NOUN
brainmatters-688	14	10	form	form	VERB
brainmatters-688	14	11	new	new	ADJ
brainmatters-688	14	12	synaptic	synaptic	ADJ
brainmatters-688	14	13	contacts	contact	NOUN
brainmatters-688	14	14	to	to	PART
brainmatters-688	14	15	replace	replace	VERB
brainmatters-688	14	16	those	those	PRON
brainmatters-688	14	17	lost	lose	VERB
brainmatters-688	14	18	,	,	PUNCT
brainmatters-688	14	19	contributing	contribute	VERB
brainmatters-688	14	20	to	to	ADP
brainmatters-688	14	21	a	a	DET
brainmatters-688	14	22	restoration	restoration	NOUN
brainmatters-688	14	23	of	of	ADP
brainmatters-688	14	24	function	function	NOUN
brainmatters-688	14	25	following	follow	VERB
brainmatters-688	14	26	brain	brain	NOUN
brainmatters-688	14	27	injury	injury	NOUN
brainmatters-688	14	28	.	.	PUNCT
brainmatters-688	15	1	as	as	ADP
brainmatters-688	15	2	a	a	DET
brainmatters-688	15	3	result	result	NOUN
brainmatters-688	15	4	,	,	PUNCT
brainmatters-688	15	5	several	several	ADJ
brainmatters-688	15	6	methods	method	NOUN
brainmatters-688	15	7	,	,	PUNCT
brainmatters-688	15	8	including	include	VERB
brainmatters-688	15	9	the	the	DET
brainmatters-688	15	10	use	use	NOUN
brainmatters-688	15	11	of	of	ADP
brainmatters-688	15	12	stem	stem	NOUN
brainmatters-688	15	13	cells	cell	NOUN
brainmatters-688	15	14	,	,	PUNCT
brainmatters-688	15	15	brain	brain	NOUN
brainmatters-688	15	16	drug	drug	NOUN
brainmatters-688	15	17	delivery	delivery	NOUN
brainmatters-688	15	18	,	,	PUNCT
brainmatters-688	15	19	and	and	CCONJ
brainmatters-688	15	20	implanting	implant	VERB
brainmatters-688	15	21	degradable	degradable	ADJ
brainmatters-688	15	22	biomaterial	biomaterial	NOUN
brainmatters-688	15	23	,	,	PUNCT
brainmatters-688	15	24	have	have	AUX
brainmatters-688	15	25	been	be	AUX
brainmatters-688	15	26	actively	actively	ADV
brainmatters-688	15	27	researched	research	VERB
brainmatters-688	15	28	to	to	PART
brainmatters-688	15	29	enhance	enhance	VERB
brainmatters-688	15	30	regeneration	regeneration	NOUN
brainmatters-688	15	31	in	in	ADP
brainmatters-688	15	32	cns	cns	PROPN
brainmatters-688	15	33	.	.	PUNCT
brainmatters-688	16	1	studies	study	NOUN
brainmatters-688	16	2	have	have	AUX
brainmatters-688	16	3	found	find	VERB
brainmatters-688	16	4	that	that	PRON
brainmatters-688	16	5	specific	specific	ADJ
brainmatters-688	16	6	brain	brain	NOUN
brainmatters-688	16	7	regions	region	NOUN
brainmatters-688	16	8	including	include	VERB
brainmatters-688	16	9	the	the	DET
brainmatters-688	16	10	subventricular	subventricular	PROPN
brainmatters-688	16	11	zone	zone	NOUN
brainmatters-688	16	12	(	(	PUNCT
brainmatters-688	16	13	svz	svz	PROPN
brainmatters-688	16	14	)	)	PUNCT
brainmatters-688	16	15	,	,	PUNCT
brainmatters-688	16	16	the	the	DET
brainmatters-688	16	17	adjacent	adjacent	ADJ
brainmatters-688	16	18	rostral	rostral	ADJ
brainmatters-688	16	19	migratory	migratory	NOUN
brainmatters-688	16	20	stream	stream	NOUN
brainmatters-688	16	21	(	(	PUNCT
brainmatters-688	16	22	rms	rm	NOUN
brainmatters-688	16	23	)	)	PUNCT
brainmatters-688	16	24	,	,	PUNCT
brainmatters-688	16	25	and	and	CCONJ
brainmatters-688	16	26	the	the	DET
brainmatters-688	16	27	circumventricular	circumventricular	ADJ
brainmatters-688	16	28	organs	organ	NOUN
brainmatters-688	16	29	(	(	PUNCT
brainmatters-688	16	30	cvos	cvos	NOUN
brainmatters-688	16	31	)	)	PUNCT
brainmatters-688	16	32	might	might	AUX
brainmatters-688	16	33	be	be	AUX
brainmatters-688	16	34	responsible	responsible	ADJ
brainmatters-688	16	35	for	for	ADP
brainmatters-688	16	36	modulating	modulate	VERB
brainmatters-688	16	37	the	the	DET
brainmatters-688	16	38	regenerative	regenerative	ADJ
brainmatters-688	16	39	ability	ability	NOUN
brainmatters-688	16	40	of	of	ADP
brainmatters-688	16	41	neural	neural	ADJ
brainmatters-688	16	42	stem	stem	NOUN
brainmatters-688	16	43	or	or	CCONJ
brainmatters-688	16	44	progenitor	progenitor	NOUN
brainmatters-688	16	45	cells	cell	NOUN
brainmatters-688	16	46	.	.	PUNCT
brainmatters-688	17	1	neural	neural	ADJ
brainmatters-688	17	2	stem	stem	NOUN
brainmatters-688	17	3	cells	cell	NOUN
brainmatters-688	17	4	that	that	PRON
brainmatters-688	17	5	are	be	AUX
brainmatters-688	17	6	possibly	possibly	ADV
brainmatters-688	17	7	responsible	responsible	ADJ
brainmatters-688	17	8	for	for	ADP
brainmatters-688	17	9	neurogenesis	neurogenesis	NOUN
brainmatters-688	17	10	are	be	AUX
brainmatters-688	17	11	expressed	express	VERB
brainmatters-688	17	12	by	by	ADP
brainmatters-688	17	13	filament	filament	NOUN
brainmatters-688	17	14	proteins	protein	NOUN
brainmatters-688	17	15	,	,	PUNCT
brainmatters-688	17	16	nestin	nestin	NOUN
brainmatters-688	17	17	,	,	PUNCT
brainmatters-688	17	18	vimentin	vimentin	ADJ
brainmatters-688	17	19	,	,	PUNCT
brainmatters-688	17	20	gfap	gfap	ADJ
brainmatters-688	17	21	,	,	PUNCT
brainmatters-688	17	22	and	and	CCONJ
brainmatters-688	17	23	transcription	transcription	NOUN
brainmatters-688	17	24	factor	factor	NOUN
brainmatters-688	17	25	sox2	sox2	NOUN
brainmatters-688	17	26	in	in	ADP
brainmatters-688	17	27	the	the	DET
brainmatters-688	17	28	svz	svz	NOUN
brainmatters-688	17	29	of	of	ADP
brainmatters-688	17	30	the	the	DET
brainmatters-688	17	31	anterolateral	anterolateral	ADJ
brainmatters-688	17	32	ventricle	ventricle	NOUN
brainmatters-688	17	33	and	and	CCONJ
brainmatters-688	17	34	subgranular	subgranular	ADJ
brainmatters-688	17	35	zone	zone	NOUN
brainmatters-688	17	36	of	of	ADP
brainmatters-688	17	37	the	the	DET
brainmatters-688	17	38	hippocampus	hippocampus	NOUN
brainmatters-688	17	39	.	.	PUNCT
brainmatters-688	18	1	similarly	similarly	ADV
brainmatters-688	18	2	,	,	PUNCT
brainmatters-688	18	3	studies	study	NOUN
brainmatters-688	18	4	using	use	VERB
brainmatters-688	18	5	rat	rat	NOUN
brainmatters-688	18	6	models	model	NOUN
brainmatters-688	18	7	identified	identify	VERB
brainmatters-688	18	8	sox2	sox2	NOUN
brainmatters-688	18	9	and	and	CCONJ
brainmatters-688	18	10	the	the	DET
brainmatters-688	18	11	cell	cell	NOUN
brainmatters-688	18	12	cycle	cycle	NOUN
brainmatters-688	18	13	-	-	PUNCT
brainmatters-688	18	14	regulating	regulate	VERB
brainmatters-688	18	15	protein	protein	NOUN
brainmatters-688	18	16	ki67	ki67	PROPN
brainmatters-688	18	17	in	in	ADP
brainmatters-688	18	18	cvos	cvos	NOUN
brainmatters-688	18	19	,	,	PUNCT
brainmatters-688	18	20	and	and	CCONJ
brainmatters-688	18	21	therefore	therefore	ADV
brainmatters-688	18	22	proposed	propose	VERB
brainmatters-688	18	23	that	that	SCONJ
brainmatters-688	18	24	cvos	cvos	NOUN
brainmatters-688	18	25	play	play	VERB
brainmatters-688	18	26	important	important	ADJ
brainmatters-688	18	27	roles	role	NOUN
brainmatters-688	18	28	in	in	ADP
brainmatters-688	18	29	stem	stem	NOUN
brainmatters-688	18	30	-	-	PUNCT
brainmatters-688	18	31	cell	cell	NOUN
brainmatters-688	18	32	based	base	VERB
brainmatters-688	18	33	neurogenesis	neurogenesis	NOUN
brainmatters-688	18	34	as	as	ADV
brainmatters-688	18	35	well	well	ADV
brainmatters-688	18	36	as	as	ADP
brainmatters-688	18	37	svz	svz	NOUN
brainmatters-688	18	38	and	and	CCONJ
brainmatters-688	18	39	rms	rm	NOUN
brainmatters-688	18	40	(	(	PUNCT
brainmatters-688	18	41	bennett	bennett	PROPN
brainmatters-688	18	42	et	et	PROPN
brainmatters-688	18	43	al	al	PROPN
brainmatters-688	18	44	.	.	PROPN
brainmatters-688	18	45	,	,	PUNCT
brainmatters-688	18	46	2009	2009	NUM
brainmatters-688	18	47	)	)	PUNCT
brainmatters-688	18	48	.	.	PUNCT
brainmatters-688	19	1	svz	svz	PROPN
brainmatters-688	19	2	,	,	PUNCT
brainmatters-688	19	3	rms	rm	NOUN
brainmatters-688	19	4	,	,	PUNCT
brainmatters-688	19	5	and	and	CCONJ
brainmatters-688	19	6	cvos	cvos	NOUN
brainmatters-688	19	7	share	share	VERB
brainmatters-688	19	8	the	the	DET
brainmatters-688	19	9	common	common	ADJ
brainmatters-688	19	10	trait	trait	NOUN
brainmatters-688	19	11	of	of	ADP
brainmatters-688	19	12	lacking	lack	VERB
brainmatters-688	19	13	protection	protection	NOUN
brainmatters-688	19	14	provided	provide	VERB
brainmatters-688	19	15	by	by	ADP
brainmatters-688	19	16	the	the	DET
brainmatters-688	19	17	blood	blood	NOUN
brainmatters-688	19	18	-	-	PUNCT
brainmatters-688	19	19	brain	brain	NOUN
brainmatters-688	19	20	barrier	barrier	NOUN
brainmatters-688	19	21	(	(	PUNCT
brainmatters-688	19	22	bbb	bbb	NOUN
brainmatters-688	19	23	)	)	PUNCT
brainmatters-688	19	24	compared	compare	VERB
brainmatters-688	19	25	to	to	ADP
brainmatters-688	19	26	other	other	ADJ
brainmatters-688	19	27	parts	part	NOUN
brainmatters-688	19	28	of	of	ADP
brainmatters-688	19	29	the	the	DET
brainmatters-688	19	30	brain	brain	NOUN
brainmatters-688	19	31	.	.	PUNCT
brainmatters-688	20	1	bbb	bbb	PROPN
brainmatters-688	20	2	is	be	AUX
brainmatters-688	20	3	a	a	DET
brainmatters-688	20	4	unique	unique	ADJ
brainmatters-688	20	5	form	form	NOUN
brainmatters-688	20	6	of	of	ADP
brainmatters-688	20	7	cellular	cellular	ADJ
brainmatters-688	20	8	membrane	membrane	NOUN
brainmatters-688	20	9	that	that	PRON
brainmatters-688	20	10	is	be	AUX
brainmatters-688	20	11	relatively	relatively	ADV
brainmatters-688	20	12	impermeable	impermeable	ADJ
brainmatters-688	20	13	compared	compare	VERB
brainmatters-688	20	14	to	to	ADP
brainmatters-688	20	15	the	the	DET
brainmatters-688	20	16	membranes	membrane	NOUN
brainmatters-688	20	17	of	of	ADP
brainmatters-688	20	18	other	other	ADJ
brainmatters-688	20	19	body	body	NOUN
brainmatters-688	20	20	parts	part	NOUN
brainmatters-688	20	21	because	because	SCONJ
brainmatters-688	20	22	its	its	PRON
brainmatters-688	20	23	capillary	capillary	ADJ
brainmatters-688	20	24	walls	wall	NOUN
brainmatters-688	20	25	have	have	VERB
brainmatters-688	20	26	no	no	DET
brainmatters-688	20	27	pores	pore	NOUN
brainmatters-688	20	28	and	and	CCONJ
brainmatters-688	20	29	the	the	DET
brainmatters-688	20	30	capillaries	capillary	NOUN
brainmatters-688	20	31	are	be	AUX
brainmatters-688	20	32	lined	line	VERB
brainmatters-688	20	33	by	by	ADP
brainmatters-688	20	34	astrocytes	astrocyte	NOUN
brainmatters-688	20	35	.	.	PUNCT
brainmatters-688	21	1	limited	limited	ADJ
brainmatters-688	21	2	permeability	permeability	NOUN
brainmatters-688	21	3	of	of	ADP
brainmatters-688	21	4	bbb	bbb	PROPN
brainmatters-688	21	5	has	have	AUX
brainmatters-688	21	6	been	be	AUX
brainmatters-688	21	7	one	one	NUM
brainmatters-688	21	8	of	of	ADP
brainmatters-688	21	9	the	the	DET
brainmatters-688	21	10	most	most	ADV
brainmatters-688	21	11	limiting	limiting	ADJ
brainmatters-688	21	12	restrictions	restriction	NOUN
brainmatters-688	21	13	in	in	ADP
brainmatters-688	21	14	brain	brain	NOUN
brainmatters-688	21	15	drug	drug	NOUN
brainmatters-688	21	16	delivery	delivery	NOUN
brainmatters-688	21	17	research	research	NOUN
brainmatters-688	21	18	.	.	PUNCT
brainmatters-688	22	1	however	however	ADV
brainmatters-688	22	2	,	,	PUNCT
brainmatters-688	22	3	because	because	SCONJ
brainmatters-688	22	4	svz	svz	PROPN
brainmatters-688	22	5	,	,	PUNCT
brainmatters-688	22	6	rms	rm	NOUN
brainmatters-688	22	7	,	,	PUNCT
brainmatters-688	22	8	and	and	CCONJ
brainmatters-688	22	9	cvos	cvos	NOUN
brainmatters-688	22	10	have	have	VERB
brainmatters-688	22	11	more	more	ADJ
brainmatters-688	22	12	“	"	PUNCT
brainmatters-688	22	13	leaky	leaky	ADJ
brainmatters-688	22	14	”	"	PUNCT
brainmatters-688	22	15	bbbs	bbb	NOUN
brainmatters-688	22	16	,	,	PUNCT
brainmatters-688	22	17	they	they	PRON
brainmatters-688	22	18	are	be	AUX
brainmatters-688	22	19	more	more	ADV
brainmatters-688	22	20	likely	likely	ADJ
brainmatters-688	22	21	to	to	PART
brainmatters-688	22	22	perceive	perceive	VERB
brainmatters-688	22	23	damage	damage	NOUN
brainmatters-688	22	24	and	and	CCONJ
brainmatters-688	22	25	engage	engage	VERB
brainmatters-688	22	26	in	in	ADP
brainmatters-688	22	27	brain	brain	NOUN
brainmatters-688	22	28	repair	repair	NOUN
brainmatters-688	22	29	by	by	ADP
brainmatters-688	22	30	producing	produce	VERB
brainmatters-688	22	31	new	new	ADJ
brainmatters-688	22	32	neurons	neuron	NOUN
brainmatters-688	22	33	which	which	PRON
brainmatters-688	22	34	cross	cross	VERB
brainmatters-688	22	35	to	to	ADP
brainmatters-688	22	36	other	other	ADJ
brainmatters-688	22	37	parts	part	NOUN
brainmatters-688	22	38	of	of	ADP
brainmatters-688	22	39	the	the	DET
brainmatters-688	22	40	brain	brain	NOUN
brainmatters-688	22	41	.	.	PUNCT
brainmatters-688	23	1	in	in	ADP
brainmatters-688	23	2	addition	addition	NOUN
brainmatters-688	23	3	,	,	PUNCT
brainmatters-688	23	4	several	several	ADJ
brainmatters-688	23	5	neuroprotective	neuroprotective	ADJ
brainmatters-688	23	6	and	and	CCONJ
brainmatters-688	23	7	neuroregenerative	neuroregenerative	ADJ
brainmatters-688	23	8	drugs	drug	NOUN
brainmatters-688	23	9	have	have	AUX
brainmatters-688	23	10	been	be	AUX
brainmatters-688	23	11	developed	develop	VERB
brainmatters-688	23	12	to	to	PART
brainmatters-688	23	13	treat	treat	VERB
brainmatters-688	23	14	neurodegenerative	neurodegenerative	ADJ
brainmatters-688	23	15	diseases	disease	NOUN
brainmatters-688	23	16	.	.	PUNCT
brainmatters-688	24	1	nevertheless	nevertheless	ADV
brainmatters-688	24	2	,	,	PUNCT
brainmatters-688	24	3	most	most	ADJ
brainmatters-688	24	4	of	of	ADP
brainmatters-688	24	5	them	they	PRON
brainmatters-688	24	6	are	be	AUX
brainmatters-688	24	7	not	not	PART
brainmatters-688	24	8	utilized	utilize	VERB
brainmatters-688	24	9	because	because	SCONJ
brainmatters-688	24	10	they	they	PRON
brainmatters-688	24	11	are	be	AUX
brainmatters-688	24	12	generally	generally	ADV
brainmatters-688	24	13	incapable	incapable	ADJ
brainmatters-688	24	14	of	of	ADP
brainmatters-688	24	15	crossing	cross	VERB
brainmatters-688	24	16	the	the	DET
brainmatters-688	24	17	bbb	bbb	PROPN
brainmatters-688	24	18	,	,	PUNCT
brainmatters-688	24	19	followed	follow	VERB
brainmatters-688	24	20	by	by	ADP
brainmatters-688	24	21	rapid	rapid	ADJ
brainmatters-688	24	22	clearance	clearance	NOUN
brainmatters-688	24	23	from	from	ADP
brainmatters-688	24	24	the	the	DET
brainmatters-688	24	25	blood	blood	NOUN
brainmatters-688	24	26	circulation	circulation	NOUN
brainmatters-688	24	27	by	by	ADP
brainmatters-688	24	28	the	the	DET
brainmatters-688	24	29	reticuloendothelial	reticuloendothelial	ADJ
brainmatters-688	24	30	system	system	NOUN
brainmatters-688	24	31	(	(	PUNCT
brainmatters-688	24	32	res	re	NOUN
brainmatters-688	24	33	)	)	PUNCT
brainmatters-688	24	34	.	.	PUNCT
brainmatters-688	25	1	for	for	ADP
brainmatters-688	25	2	example	example	NOUN
brainmatters-688	25	3	,	,	PUNCT
brainmatters-688	25	4	molecules	molecule	NOUN
brainmatters-688	25	5	like	like	ADP
brainmatters-688	25	6	z	z	NOUN
brainmatters-688	25	7	-	-	PUNCT
brainmatters-688	25	8	devd	devd	NOUN
brainmatters-688	25	9	-	-	PUNCT
brainmatters-688	25	10	fmk	fmk	PROPN
brainmatters-688	25	11	and	and	CCONJ
brainmatters-688	25	12	basic	basic	ADJ
brainmatters-688	25	13	fibroblast	fibroblast	ADJ
brainmatters-688	25	14	growth	growth	NOUN
brainmatters-688	25	15	factor	factor	NOUN
brainmatters-688	25	16	(	(	PUNCT
brainmatters-688	25	17	bfgf	bfgf	NOUN
brainmatters-688	25	18	)	)	PUNCT
brainmatters-688	25	19	were	be	AUX
brainmatters-688	25	20	found	find	VERB
brainmatters-688	25	21	to	to	PART
brainmatters-688	25	22	significantly	significantly	ADV
brainmatters-688	25	23	induce	induce	VERB
brainmatters-688	25	24	neuroregeneration	neuroregeneration	NOUN
brainmatters-688	25	25	in	in	ADP
brainmatters-688	25	26	in	in	ADP
brainmatters-688	25	27	vitro	vitro	X
brainmatters-688	25	28	studies	study	NOUN
brainmatters-688	25	29	.	.	PUNCT
brainmatters-688	26	1	however	however	ADV
brainmatters-688	26	2	,	,	PUNCT
brainmatters-688	26	3	neither	neither	CCONJ
brainmatters-688	26	4	can	can	AUX
brainmatters-688	26	5	pass	pass	VERB
brainmatters-688	26	6	the	the	DET
brainmatters-688	26	7	bbb	bbb	NOUN
brainmatters-688	26	8	in	in	ADP
brainmatters-688	26	9	their	their	PRON
brainmatters-688	26	10	free	free	ADJ
brainmatters-688	26	11	form	form	NOUN
brainmatters-688	26	12	or	or	CCONJ
brainmatters-688	26	13	do	do	VERB
brainmatters-688	26	14	so	so	ADV
brainmatters-688	26	15	in	in	ADP
brainmatters-688	26	16	very	very	ADV
brainmatters-688	26	17	low	low	ADJ
brainmatters-688	26	18	amounts	amount	NOUN
brainmatters-688	26	19	,	,	PUNCT
brainmatters-688	26	20	displaying	display	VERB
brainmatters-688	26	21	limited	limited	ADJ
brainmatters-688	26	22	efficacy	efficacy	NOUN
brainmatters-688	26	23	in	in	ADP
brainmatters-688	26	24	potential	potential	ADJ
brainmatters-688	26	25	clinical	clinical	ADJ
brainmatters-688	26	26	uses	use	NOUN
brainmatters-688	26	27	(	(	PUNCT
brainmatters-688	26	28	yemisci	yemisci	X
brainmatters-688	26	29	et	et	PROPN
brainmatters-688	26	30	al	al	PROPN
brainmatters-688	26	31	,	,	PUNCT
brainmatters-688	26	32	2015	2015	NUM
brainmatters-688	26	33	)	)	PUNCT
brainmatters-688	26	34	.	.	PUNCT
brainmatters-688	27	1	thus	thus	ADV
brainmatters-688	27	2	,	,	PUNCT
brainmatters-688	27	3	to	to	PART
brainmatters-688	27	4	stimulate	stimulate	VERB
brainmatters-688	27	5	these	these	DET
brainmatters-688	27	6	brain	brain	NOUN
brainmatters-688	27	7	regions	region	NOUN
brainmatters-688	27	8	and	and	CCONJ
brainmatters-688	27	9	to	to	PART
brainmatters-688	27	10	utilize	utilize	VERB
brainmatters-688	27	11	the	the	DET
brainmatters-688	27	12	drug	drug	NOUN
brainmatters-688	27	13	molecules	molecule	NOUN
brainmatters-688	27	14	that	that	PRON
brainmatters-688	27	15	have	have	AUX
brainmatters-688	27	16	been	be	AUX
brainmatters-688	27	17	found	find	VERB
brainmatters-688	27	18	to	to	PART
brainmatters-688	27	19	contribute	contribute	VERB
brainmatters-688	27	20	to	to	ADP
brainmatters-688	27	21	neurogenesis	neurogenesis	VERB
brainmatters-688	27	22	,	,	PUNCT
brainmatters-688	27	23	intravenous	intravenous	ADJ
brainmatters-688	27	24	injection	injection	NOUN
brainmatters-688	27	25	of	of	ADP
brainmatters-688	27	26	nanoparticles	nanoparticle	NOUN
brainmatters-688	27	27	(	(	PUNCT
brainmatters-688	27	28	np	np	NOUN
brainmatters-688	27	29	)	)	PUNCT
brainmatters-688	27	30	figure	figure	NOUN
brainmatters-688	27	31	1	1	NUM
brainmatters-688	27	32	.	.	PUNCT
brainmatters-688	27	33	locations	location	NOUN
brainmatters-688	27	34	of	of	ADP
brainmatters-688	27	35	svz	svz	NOUN
brainmatters-688	27	36	and	and	CCONJ
brainmatters-688	27	37	rms	rm	NOUN
brainmatters-688	27	38	(	(	PUNCT
brainmatters-688	27	39	chang	chang	PROPN
brainmatters-688	27	40	et	et	PROPN
brainmatters-688	27	41	al	al	PROPN
brainmatters-688	27	42	.	.	PROPN
brainmatters-688	27	43	,	,	PUNCT
brainmatters-688	27	44	2016	2016	NUM
brainmatters-688	27	45	)	)	PUNCT
brainmatters-688	27	46	.	.	PUNCT
brainmatters-688	28	1	these	these	DET
brainmatters-688	28	2	regions	region	NOUN
brainmatters-688	28	3	are	be	AUX
brainmatters-688	28	4	located	locate	VERB
brainmatters-688	28	5	near	near	ADP
brainmatters-688	28	6	the	the	DET
brainmatters-688	28	7	occipital	occipital	NOUN
brainmatters-688	28	8	lobe	lobe	NOUN
brainmatters-688	28	9	of	of	ADP
brainmatters-688	28	10	the	the	DET
brainmatters-688	28	11	brain	brain	NOUN
brainmatters-688	28	12	and	and	CCONJ
brainmatters-688	28	13	serve	serve	VERB
brainmatters-688	28	14	as	as	ADP
brainmatters-688	28	15	possible	possible	ADJ
brainmatters-688	28	16	sources	source	NOUN
brainmatters-688	28	17	of	of	ADP
brainmatters-688	28	18	stem	stem	NOUN
brainmatters-688	28	19	cell	cell	NOUN
brainmatters-688	28	20	regulation	regulation	NOUN
brainmatters-688	28	21	.	.	PUNCT
brainmatters-688	29	1	figure	figure	NOUN
brainmatters-688	29	2	2	2	NUM
brainmatters-688	29	3	.	.	PUNCT
brainmatters-688	30	1	nanoparticles	nanoparticle	NOUN
brainmatters-688	30	2	delivered	deliver	VERB
brainmatters-688	30	3	into	into	ADP
brainmatters-688	30	4	brain	brain	NOUN
brainmatters-688	30	5	regions	region	NOUN
brainmatters-688	30	6	(	(	PUNCT
brainmatters-688	30	7	long	long	ADV
brainmatters-688	30	8	et	et	PROPN
brainmatters-688	30	9	al	al	PROPN
brainmatters-688	30	10	.	.	PROPN
brainmatters-688	30	11	,	,	PUNCT
brainmatters-688	30	12	2017	2017	NUM
brainmatters-688	30	13	)	)	PUNCT
brainmatters-688	30	14	.	.	PUNCT
brainmatters-688	31	1	the	the	DET
brainmatters-688	31	2	msc	msc	PROPN
brainmatters-688	31	3	and	and	CCONJ
brainmatters-688	31	4	nscs	nscs	PROPN
brainmatters-688	31	5	are	be	AUX
brainmatters-688	31	6	types	type	NOUN
brainmatters-688	31	7	of	of	ADP
brainmatters-688	31	8	stem	stem	NOUN
brainmatters-688	31	9	cells	cell	NOUN
brainmatters-688	31	10	that	that	PRON
brainmatters-688	31	11	can	can	AUX
brainmatters-688	31	12	carry	carry	VERB
brainmatters-688	31	13	nanoparticles	nanoparticle	NOUN
brainmatters-688	31	14	into	into	ADP
brainmatters-688	31	15	the	the	DET
brainmatters-688	31	16	brain	brain	NOUN
brainmatters-688	31	17	and	and	CCONJ
brainmatters-688	31	18	allow	allow	VERB
brainmatters-688	31	19	for	for	ADP
brainmatters-688	31	20	transfusion	transfusion	NOUN
brainmatters-688	31	21	and	and	CCONJ
brainmatters-688	31	22	delivery	delivery	NOUN
brainmatters-688	31	23	of	of	ADP
brainmatters-688	31	24	the	the	DET
brainmatters-688	31	25	desired	desire	VERB
brainmatters-688	31	26	drug	drug	NOUN
brainmatters-688	31	27	,	,	PUNCT
brainmatters-688	31	28	which	which	PRON
brainmatters-688	31	29	has	have	AUX
brainmatters-688	31	30	been	be	AUX
brainmatters-688	31	31	experimented	experiment	VERB
brainmatters-688	31	32	with	with	ADP
brainmatters-688	31	33	for	for	ADP
brainmatters-688	31	34	in	in	ADP
brainmatters-688	31	35	vivo	vivo	ADJ
brainmatters-688	31	36	studies	study	NOUN
brainmatters-688	31	37	.	.	PUNCT
brainmatters-688	32	1	brain	brain	NOUN
brainmatters-688	32	2	matters	matter	NOUN
brainmatters-688	32	3	volume	volume	VERB
brainmatters-688	32	4	2	2	NUM
brainmatters-688	32	5	6	6	NUM
brainmatters-688	32	6	through	through	ADV
brainmatters-688	32	7	.	.	PUNCT
brainmatters-688	33	1	nps	nps	PROPN
brainmatters-688	33	2	are	be	AUX
brainmatters-688	33	3	well	well	ADV
brainmatters-688	33	4	-	-	PUNCT
brainmatters-688	33	5	defined	define	VERB
brainmatters-688	33	6	particles	particle	NOUN
brainmatters-688	33	7	ranging	range	VERB
brainmatters-688	33	8	in	in	ADP
brainmatters-688	33	9	sizes	size	NOUN
brainmatters-688	33	10	of	of	ADP
brainmatters-688	33	11	approximately	approximately	ADV
brainmatters-688	33	12	10	10	NUM
brainmatters-688	33	13	to	to	PART
brainmatters-688	33	14	1000	1000	NUM
brainmatters-688	33	15	nm	nm	NOUN
brainmatters-688	33	16	(	(	PUNCT
brainmatters-688	33	17	1	1	NUM
brainmatters-688	33	18	μm	μm	NUM
brainmatters-688	33	19	)	)	PUNCT
brainmatters-688	33	20	with	with	ADP
brainmatters-688	33	21	a	a	DET
brainmatters-688	33	22	core	core	ADJ
brainmatters-688	33	23	-	-	PUNCT
brainmatters-688	33	24	shell	shell	NOUN
brainmatters-688	33	25	structure	structure	NOUN
brainmatters-688	33	26	(	(	PUNCT
brainmatters-688	33	27	nanocapsules	nanocapsule	NOUN
brainmatters-688	33	28	)	)	PUNCT
brainmatters-688	33	29	or	or	CCONJ
brainmatters-688	33	30	a	a	DET
brainmatters-688	33	31	continuous	continuous	ADJ
brainmatters-688	33	32	matrix	matrix	NOUN
brainmatters-688	33	33	structure	structure	NOUN
brainmatters-688	33	34	(	(	PUNCT
brainmatters-688	33	35	nanospheres	nanosphere	NOUN
brainmatters-688	33	36	)	)	PUNCT
brainmatters-688	33	37	(	(	PUNCT
brainmatters-688	33	38	kreuter	kreuter	NOUN
brainmatters-688	33	39	,	,	PUNCT
brainmatters-688	33	40	2014	2014	NUM
brainmatters-688	33	41	)	)	PUNCT
brainmatters-688	33	42	.	.	PUNCT
brainmatters-688	34	1	researchers	researcher	NOUN
brainmatters-688	34	2	have	have	AUX
brainmatters-688	34	3	uncovered	uncover	VERB
brainmatters-688	34	4	that	that	PRON
brainmatters-688	34	5	specific	specific	ADJ
brainmatters-688	34	6	forms	form	NOUN
brainmatters-688	34	7	of	of	ADP
brainmatters-688	34	8	np	np	INTJ
brainmatters-688	34	9	(	(	PUNCT
brainmatters-688	34	10	angiopep	angiopep	NOUN
brainmatters-688	34	11	-	-	PUNCT
brainmatters-688	34	12	conjugated	conjugate	VERB
brainmatters-688	34	13	poly(ethylene	poly(ethylene	PROPN
brainmatters-688	34	14	glycol)-copoly(ɛ	glycol)-copoly(ɛ	NOUN
brainmatters-688	34	15	-	-	PUNCT
brainmatters-688	34	16	caprolactone	caprolactone	NOUN
brainmatters-688	34	17	)	)	PUNCT
brainmatters-688	34	18	nanoparticles	nanoparticle	NOUN
brainmatters-688	34	19	or	or	CCONJ
brainmatters-688	34	20	ang	ang	NOUN
brainmatters-688	34	21	-	-	PUNCT
brainmatters-688	34	22	peg	peg	NOUN
brainmatters-688	34	23	-	-	PUNCT
brainmatters-688	34	24	nps	nps	NOUN
brainmatters-688	34	25	)	)	PUNCT
brainmatters-688	34	26	pass	pass	VERB
brainmatters-688	34	27	through	through	ADP
brainmatters-688	34	28	the	the	DET
brainmatters-688	34	29	bbb	bbb	NOUN
brainmatters-688	34	30	and	and	CCONJ
brainmatters-688	34	31	accumulate	accumulate	VERB
brainmatters-688	34	32	in	in	ADP
brainmatters-688	34	33	certain	certain	ADJ
brainmatters-688	34	34	brain	brain	NOUN
brainmatters-688	34	35	areas	area	NOUN
brainmatters-688	34	36	such	such	ADJ
brainmatters-688	34	37	as	as	ADP
brainmatters-688	34	38	the	the	DET
brainmatters-688	34	39	ventricles	ventricle	NOUN
brainmatters-688	34	40	,	,	PUNCT
brainmatters-688	34	41	hippocampus	hippocampus	NOUN
brainmatters-688	34	42	,	,	PUNCT
brainmatters-688	34	43	and	and	CCONJ
brainmatters-688	34	44	cortical	cortical	ADJ
brainmatters-688	34	45	layer	layer	NOUN
brainmatters-688	34	46	.	.	PUNCT
brainmatters-688	35	1	also	also	ADV
brainmatters-688	35	2	,	,	PUNCT
brainmatters-688	35	3	chitosan	chitosan	PROPN
brainmatters-688	35	4	nps	nps	PROPN
brainmatters-688	35	5	and	and	CCONJ
brainmatters-688	35	6	cationic	cationic	ADJ
brainmatters-688	35	7	bovine	bovine	NOUN
brainmatters-688	35	8	serum	serum	NOUN
brainmatters-688	35	9	albumin	albumin	NOUN
brainmatters-688	35	10	-	-	PUNCT
brainmatters-688	35	11	conjugated	conjugate	VERB
brainmatters-688	35	12	tanshinone	tanshinone	PROPN
brainmatters-688	35	13	iia	iia	PROPN
brainmatters-688	35	14	pegylated	pegylate	VERB
brainmatters-688	35	15	nps	nps	PROPN
brainmatters-688	35	16	showed	show	VERB
brainmatters-688	35	17	promising	promising	ADJ
brainmatters-688	35	18	results	result	NOUN
brainmatters-688	35	19	in	in	ADP
brainmatters-688	35	20	crossing	cross	VERB
brainmatters-688	35	21	the	the	DET
brainmatters-688	35	22	bbb	bbb	NOUN
brainmatters-688	35	23	and	and	CCONJ
brainmatters-688	35	24	therefore	therefore	ADV
brainmatters-688	35	25	increase	increase	VERB
brainmatters-688	35	26	drug	drug	NOUN
brainmatters-688	35	27	efficacy	efficacy	NOUN
brainmatters-688	35	28	.	.	PUNCT
brainmatters-688	36	1	moreover	moreover	ADV
brainmatters-688	36	2	,	,	PUNCT
brainmatters-688	36	3	these	these	DET
brainmatters-688	36	4	nps	nps	PROPN
brainmatters-688	36	5	have	have	VERB
brainmatters-688	36	6	the	the	DET
brainmatters-688	36	7	inherent	inherent	ADJ
brainmatters-688	36	8	ability	ability	NOUN
brainmatters-688	36	9	to	to	PART
brainmatters-688	36	10	elicit	elicit	VERB
brainmatters-688	36	11	neuroprotective	neuroprotective	ADJ
brainmatters-688	36	12	effects	effect	NOUN
brainmatters-688	36	13	by	by	ADP
brainmatters-688	36	14	themselves	themselves	PRON
brainmatters-688	36	15	.	.	PUNCT
brainmatters-688	37	1	for	for	ADP
brainmatters-688	37	2	example	example	NOUN
brainmatters-688	37	3	,	,	PUNCT
brainmatters-688	37	4	by	by	ADP
brainmatters-688	37	5	down	down	ADV
brainmatters-688	37	6	-	-	PUNCT
brainmatters-688	37	7	regulating	regulate	VERB
brainmatters-688	37	8	pro	pro	ADJ
brainmatters-688	37	9	-	-	ADJ
brainmatters-688	37	10	inflammatory	inflammatory	ADJ
brainmatters-688	37	11	cytokines	cytokine	NOUN
brainmatters-688	37	12	,	,	PUNCT
brainmatters-688	37	13	up	up	ADV
brainmatters-688	37	14	-	-	PUNCT
brainmatters-688	37	15	regulating	regulate	VERB
brainmatters-688	37	16	anti	anti	ADJ
brainmatters-688	37	17	-	-	ADJ
brainmatters-688	37	18	inflammatory	inflammatory	ADJ
brainmatters-688	37	19	cytokines	cytokine	NOUN
brainmatters-688	37	20	and	and	CCONJ
brainmatters-688	37	21	transforming	transform	VERB
brainmatters-688	37	22	growth	growth	NOUN
brainmatters-688	37	23	factor	factor	NOUN
brainmatters-688	37	24	-	-	PUNCT
brainmatters-688	37	25	β1	β1	PROPN
brainmatters-688	37	26	(	(	PUNCT
brainmatters-688	37	27	tgf	tgf	PROPN
brainmatters-688	37	28	-	-	PUNCT
brainmatters-688	37	29	β1	β1	PROPN
brainmatters-688	37	30	)	)	PUNCT
brainmatters-688	37	31	these	these	DET
brainmatters-688	37	32	nps	nps	PROPN
brainmatters-688	37	33	modulate	modulate	VERB
brainmatters-688	37	34	inflammatory	inflammatory	ADJ
brainmatters-688	37	35	processes	process	NOUN
brainmatters-688	37	36	and	and	CCONJ
brainmatters-688	37	37	neuronal	neuronal	ADJ
brainmatters-688	37	38	signaling	signal	VERB
brainmatters-688	37	39	pathways	pathway	NOUN
brainmatters-688	37	40	(	(	PUNCT
brainmatters-688	37	41	saraiva	saraiva	NOUN
brainmatters-688	37	42	et	et	PROPN
brainmatters-688	37	43	al	al	PROPN
brainmatters-688	37	44	.	.	PROPN
brainmatters-688	37	45	,	,	PUNCT
brainmatters-688	37	46	2016	2016	NUM
brainmatters-688	37	47	)	)	PUNCT
brainmatters-688	37	48	.	.	PUNCT
brainmatters-688	38	1	more	more	ADV
brainmatters-688	38	2	specifically	specifically	ADV
brainmatters-688	38	3	,	,	PUNCT
brainmatters-688	38	4	among	among	ADP
brainmatters-688	38	5	other	other	ADJ
brainmatters-688	38	6	np	np	PROPN
brainmatters-688	38	7	formulations	formulation	NOUN
brainmatters-688	38	8	,	,	PUNCT
brainmatters-688	38	9	solid	solid	ADJ
brainmatters-688	38	10	lipid	lipid	NOUN
brainmatters-688	38	11	nanoparticles	nanoparticle	NOUN
brainmatters-688	38	12	(	(	PUNCT
brainmatters-688	38	13	slns	slns	NOUN
brainmatters-688	38	14	)	)	PUNCT
brainmatters-688	38	15	are	be	AUX
brainmatters-688	38	16	expected	expect	VERB
brainmatters-688	38	17	to	to	PART
brainmatters-688	38	18	enhance	enhance	VERB
brainmatters-688	38	19	efficiency	efficiency	NOUN
brainmatters-688	38	20	in	in	ADP
brainmatters-688	38	21	brain	brain	NOUN
brainmatters-688	38	22	-	-	PUNCT
brainmatters-688	38	23	targeted	target	VERB
brainmatters-688	38	24	drug	drug	NOUN
brainmatters-688	38	25	delivery	delivery	NOUN
brainmatters-688	38	26	system	system	NOUN
brainmatters-688	38	27	.	.	PUNCT
brainmatters-688	39	1	in	in	ADP
brainmatters-688	39	2	the	the	DET
brainmatters-688	39	3	late	late	ADJ
brainmatters-688	39	4	1900s	1900	NOUN
brainmatters-688	39	5	,	,	PUNCT
brainmatters-688	39	6	researchers	researcher	NOUN
brainmatters-688	39	7	found	find	VERB
brainmatters-688	39	8	that	that	SCONJ
brainmatters-688	39	9	surfactant	surfactant	ADJ
brainmatters-688	39	10	coating	coating	NOUN
brainmatters-688	39	11	on	on	ADP
brainmatters-688	39	12	nps	nps	PROPN
brainmatters-688	39	13	increases	increase	VERB
brainmatters-688	39	14	blood	blood	NOUN
brainmatters-688	40	1	np	np	INTJ
brainmatters-688	40	2	level	level	NOUN
brainmatters-688	40	3	along	along	ADP
brainmatters-688	40	4	with	with	ADP
brainmatters-688	40	5	the	the	DET
brainmatters-688	40	6	total	total	ADJ
brainmatters-688	40	7	np	np	INTJ
brainmatters-688	40	8	brain	brain	NOUN
brainmatters-688	40	9	amount	amount	NOUN
brainmatters-688	40	10	in	in	ADV
brainmatters-688	40	11	in	in	ADP
brainmatters-688	40	12	vivo	vivo	ADJ
brainmatters-688	40	13	studies	study	NOUN
brainmatters-688	40	14	.	.	PUNCT
brainmatters-688	41	1	several	several	ADJ
brainmatters-688	41	2	mechanisms	mechanism	NOUN
brainmatters-688	41	3	were	be	AUX
brainmatters-688	41	4	proposed	propose	VERB
brainmatters-688	41	5	to	to	PART
brainmatters-688	41	6	explain	explain	VERB
brainmatters-688	41	7	this	this	DET
brainmatters-688	41	8	increase	increase	NOUN
brainmatters-688	41	9	,	,	PUNCT
brainmatters-688	41	10	one	one	NUM
brainmatters-688	41	11	being	be	AUX
brainmatters-688	41	12	that	that	PRON
brainmatters-688	41	13	increased	increase	VERB
brainmatters-688	41	14	np	np	PRON
brainmatters-688	41	15	retention	retention	NOUN
brainmatters-688	41	16	in	in	ADP
brainmatters-688	41	17	the	the	DET
brainmatters-688	41	18	brain	brain	NOUN
brainmatters-688	41	19	blood	blood	NOUN
brainmatters-688	41	20	capillaries	capillary	NOUN
brainmatters-688	41	21	,	,	PUNCT
brainmatters-688	41	22	and	and	CCONJ
brainmatters-688	41	23	their	their	PRON
brainmatters-688	41	24	absorption	absorption	NOUN
brainmatters-688	41	25	into	into	ADP
brainmatters-688	41	26	the	the	DET
brainmatters-688	41	27	capillary	capillary	ADJ
brainmatters-688	41	28	walls	wall	NOUN
brainmatters-688	41	29	may	may	AUX
brainmatters-688	41	30	create	create	VERB
brainmatters-688	41	31	a	a	DET
brainmatters-688	41	32	higher	high	ADJ
brainmatters-688	41	33	concentration	concentration	NOUN
brainmatters-688	41	34	gradient	gradient	NOUN
brainmatters-688	41	35	,	,	PUNCT
brainmatters-688	41	36	which	which	PRON
brainmatters-688	41	37	enhances	enhance	VERB
brainmatters-688	41	38	transportation	transportation	NOUN
brainmatters-688	41	39	across	across	ADP
brainmatters-688	41	40	the	the	DET
brainmatters-688	41	41	bbb	bbb	PROPN
brainmatters-688	41	42	,	,	PUNCT
brainmatters-688	41	43	leading	lead	VERB
brainmatters-688	41	44	to	to	ADP
brainmatters-688	41	45	brain	brain	NOUN
brainmatters-688	41	46	drug	drug	NOUN
brainmatters-688	41	47	accumulation	accumulation	NOUN
brainmatters-688	41	48	.	.	PUNCT
brainmatters-688	42	1	another	another	DET
brainmatters-688	42	2	explanation	explanation	NOUN
brainmatters-688	42	3	may	may	AUX
brainmatters-688	42	4	be	be	AUX
brainmatters-688	42	5	that	that	SCONJ
brainmatters-688	42	6	np	np	PROPN
brainmatters-688	42	7	endocytosis	endocytosis	NOUN
brainmatters-688	42	8	by	by	ADP
brainmatters-688	42	9	endothelial	endothelial	ADJ
brainmatters-688	42	10	cells	cell	NOUN
brainmatters-688	42	11	can	can	AUX
brainmatters-688	42	12	permit	permit	VERB
brainmatters-688	42	13	the	the	DET
brainmatters-688	42	14	drug	drug	NOUN
brainmatters-688	42	15	release	release	NOUN
brainmatters-688	42	16	within	within	ADP
brainmatters-688	42	17	these	these	DET
brainmatters-688	42	18	cells	cell	NOUN
brainmatters-688	42	19	and	and	CCONJ
brainmatters-688	42	20	the	the	DET
brainmatters-688	42	21	following	follow	VERB
brainmatters-688	42	22	drug	drug	NOUN
brainmatters-688	42	23	diffusion	diffusion	NOUN
brainmatters-688	42	24	in	in	ADP
brainmatters-688	42	25	the	the	DET
brainmatters-688	42	26	brain	brain	NOUN
brainmatters-688	42	27	parenchyma	parenchyma	NOUN
brainmatters-688	42	28	,	,	PUNCT
brainmatters-688	42	29	or	or	CCONJ
brainmatters-688	42	30	the	the	DET
brainmatters-688	42	31	transcytosis	transcytosis	NOUN
brainmatters-688	42	32	of	of	ADP
brainmatters-688	42	33	nps	nps	PROPN
brainmatters-688	42	34	with	with	ADP
brainmatters-688	42	35	the	the	DET
brainmatters-688	42	36	bound	bind	VERB
brainmatters-688	42	37	drug	drug	NOUN
brainmatters-688	42	38	can	can	AUX
brainmatters-688	42	39	release	release	VERB
brainmatters-688	42	40	directly	directly	ADV
brainmatters-688	42	41	into	into	ADP
brainmatters-688	42	42	the	the	DET
brainmatters-688	42	43	brain	brain	NOUN
brainmatters-688	42	44	parenchyma	parenchyma	NOUN
brainmatters-688	42	45	,	,	PUNCT
brainmatters-688	42	46	along	along	ADP
brainmatters-688	42	47	with	with	ADP
brainmatters-688	42	48	multiple	multiple	ADJ
brainmatters-688	42	49	other	other	ADJ
brainmatters-688	42	50	possible	possible	ADJ
brainmatters-688	42	51	explanations	explanation	NOUN
brainmatters-688	42	52	.	.	PUNCT
brainmatters-688	43	1	although	although	SCONJ
brainmatters-688	43	2	these	these	DET
brainmatters-688	43	3	mechanisms	mechanism	NOUN
brainmatters-688	43	4	are	be	AUX
brainmatters-688	43	5	still	still	ADV
brainmatters-688	43	6	being	be	AUX
brainmatters-688	43	7	studied	study	VERB
brainmatters-688	43	8	,	,	PUNCT
brainmatters-688	43	9	previous	previous	ADJ
brainmatters-688	43	10	experimental	experimental	ADJ
brainmatters-688	43	11	results	result	NOUN
brainmatters-688	43	12	have	have	AUX
brainmatters-688	43	13	shown	show	VERB
brainmatters-688	43	14	that	that	SCONJ
brainmatters-688	43	15	the	the	DET
brainmatters-688	43	16	use	use	NOUN
brainmatters-688	43	17	of	of	ADP
brainmatters-688	43	18	surfactant	surfactant	NOUN
brainmatters-688	43	19	-	-	PUNCT
brainmatters-688	43	20	coated	coat	VERB
brainmatters-688	43	21	slns	slns	NOUN
brainmatters-688	43	22	plays	play	VERB
brainmatters-688	43	23	a	a	DET
brainmatters-688	43	24	role	role	NOUN
brainmatters-688	43	25	in	in	ADP
brainmatters-688	43	26	brain	brain	NOUN
brainmatters-688	43	27	-	-	PUNCT
brainmatters-688	43	28	targeting	target	VERB
brainmatters-688	43	29	drug	drug	NOUN
brainmatters-688	43	30	delivery	delivery	NOUN
brainmatters-688	43	31	that	that	PRON
brainmatters-688	43	32	induces	induce	VERB
brainmatters-688	43	33	neural	neural	ADJ
brainmatters-688	43	34	regeneration	regeneration	NOUN
brainmatters-688	43	35	as	as	ADP
brainmatters-688	43	36	a	a	DET
brainmatters-688	43	37	possible	possible	ADJ
brainmatters-688	43	38	treatment	treatment	NOUN
brainmatters-688	43	39	to	to	ADP
brainmatters-688	43	40	neurodegenerative	neurodegenerative	ADJ
brainmatters-688	43	41	diseases	disease	NOUN
brainmatters-688	43	42	(	(	PUNCT
brainmatters-688	43	43	blasi	blasi	PROPN
brainmatters-688	43	44	et	et	PROPN
brainmatters-688	43	45	al	al	PROPN
brainmatters-688	43	46	.	.	PROPN
brainmatters-688	43	47	,	,	PUNCT
brainmatters-688	43	48	2007	2007	NUM
brainmatters-688	43	49	)	)	PUNCT
brainmatters-688	43	50	.	.	PUNCT
brainmatters-688	44	1	another	another	DET
brainmatters-688	44	2	way	way	NOUN
brainmatters-688	44	3	to	to	PART
brainmatters-688	44	4	induce	induce	VERB
brainmatters-688	44	5	enhance	enhance	NOUN
brainmatters-688	44	6	neuroregeneration	neuroregeneration	NOUN
brainmatters-688	44	7	is	be	AUX
brainmatters-688	44	8	to	to	PART
brainmatters-688	44	9	directly	directly	ADV
brainmatters-688	44	10	implant	implant	VERB
brainmatters-688	44	11	active	active	ADJ
brainmatters-688	44	12	biomaterials	biomaterial	NOUN
brainmatters-688	44	13	such	such	ADJ
brainmatters-688	44	14	as	as	ADP
brainmatters-688	44	15	hydrogels	hydrogel	NOUN
brainmatters-688	44	16	.	.	PUNCT
brainmatters-688	45	1	hydrogels	hydrogel	NOUN
brainmatters-688	45	2	are	be	AUX
brainmatters-688	45	3	used	use	VERB
brainmatters-688	45	4	in	in	ADP
brainmatters-688	45	5	the	the	DET
brainmatters-688	45	6	same	same	ADJ
brainmatters-688	45	7	drug	drug	NOUN
brainmatters-688	45	8	delivery	delivery	NOUN
brainmatters-688	45	9	system	system	NOUN
brainmatters-688	45	10	as	as	ADP
brainmatters-688	45	11	nps	nps	PROPN
brainmatters-688	45	12	but	but	CCONJ
brainmatters-688	45	13	act	act	VERB
brainmatters-688	45	14	differently	differently	ADV
brainmatters-688	45	15	through	through	ADP
brainmatters-688	45	16	inducing	induce	VERB
brainmatters-688	45	17	neurogenesis	neurogenesis	NOUN
brainmatters-688	45	18	by	by	ADP
brainmatters-688	45	19	mimicking	mimic	VERB
brainmatters-688	45	20	neural	neural	ADJ
brainmatters-688	45	21	growth	growth	NOUN
brainmatters-688	45	22	conditions	condition	NOUN
brainmatters-688	45	23	.	.	PUNCT
brainmatters-688	46	1	biomaterials	biomaterial	NOUN
brainmatters-688	46	2	can	can	AUX
brainmatters-688	46	3	be	be	AUX
brainmatters-688	46	4	useful	useful	ADJ
brainmatters-688	46	5	because	because	SCONJ
brainmatters-688	46	6	the	the	DET
brainmatters-688	46	7	systemic	systemic	ADJ
brainmatters-688	46	8	delivery	delivery	NOUN
brainmatters-688	46	9	of	of	ADP
brainmatters-688	46	10	pharmaceuticals	pharmaceutical	NOUN
brainmatters-688	46	11	usually	usually	ADV
brainmatters-688	46	12	results	result	VERB
brainmatters-688	46	13	in	in	ADP
brainmatters-688	46	14	reduced	reduce	VERB
brainmatters-688	46	15	efficacy	efficacy	NOUN
brainmatters-688	46	16	over	over	ADP
brainmatters-688	46	17	time	time	NOUN
brainmatters-688	46	18	.	.	PUNCT
brainmatters-688	47	1	this	this	PRON
brainmatters-688	47	2	is	be	AUX
brainmatters-688	47	3	predominantly	predominantly	ADV
brainmatters-688	47	4	due	due	ADJ
brainmatters-688	47	5	to	to	ADP
brainmatters-688	47	6	failure	failure	NOUN
brainmatters-688	47	7	to	to	PART
brainmatters-688	47	8	meet	meet	VERB
brainmatters-688	47	9	the	the	DET
brainmatters-688	47	10	needs	need	NOUN
brainmatters-688	47	11	for	for	ADP
brainmatters-688	47	12	continuous	continuous	ADJ
brainmatters-688	47	13	drug	drug	NOUN
brainmatters-688	47	14	delivery	delivery	NOUN
brainmatters-688	47	15	,	,	PUNCT
brainmatters-688	47	16	along	along	ADP
brainmatters-688	47	17	with	with	ADP
brainmatters-688	47	18	possible	possible	ADJ
brainmatters-688	47	19	side	side	NOUN
brainmatters-688	47	20	effects	effect	NOUN
brainmatters-688	47	21	followed	follow	VERB
brainmatters-688	47	22	by	by	ADP
brainmatters-688	47	23	repeated	repeat	VERB
brainmatters-688	47	24	drug	drug	NOUN
brainmatters-688	47	25	administration	administration	NOUN
brainmatters-688	47	26	(	(	PUNCT
brainmatters-688	47	27	gerndt	gerndt	PROPN
brainmatters-688	47	28	et	et	PROPN
brainmatters-688	47	29	al	al	PROPN
brainmatters-688	47	30	.	.	PROPN
brainmatters-688	47	31	,	,	PUNCT
brainmatters-688	47	32	1997	1997	NUM
brainmatters-688	47	33	)	)	PUNCT
brainmatters-688	47	34	.	.	PUNCT
brainmatters-688	48	1	in	in	ADP
brainmatters-688	48	2	treatments	treatment	NOUN
brainmatters-688	48	3	of	of	ADP
brainmatters-688	48	4	spinal	spinal	ADJ
brainmatters-688	48	5	cord	cord	NOUN
brainmatters-688	48	6	injury	injury	NOUN
brainmatters-688	48	7	(	(	PUNCT
brainmatters-688	48	8	sci	sci	PROPN
brainmatters-688	48	9	)	)	PUNCT
brainmatters-688	48	10	,	,	PUNCT
brainmatters-688	48	11	the	the	DET
brainmatters-688	48	12	drug	drug	NOUN
brainmatters-688	48	13	-	-	PUNCT
brainmatters-688	48	14	releasing	release	VERB
brainmatters-688	48	15	biomaterial	biomaterial	NOUN
brainmatters-688	48	16	has	have	AUX
brainmatters-688	48	17	been	be	AUX
brainmatters-688	48	18	proposed	propose	VERB
brainmatters-688	48	19	as	as	ADP
brainmatters-688	48	20	a	a	DET
brainmatters-688	48	21	new	new	ADJ
brainmatters-688	48	22	solution	solution	NOUN
brainmatters-688	48	23	to	to	PART
brainmatters-688	48	24	overcome	overcome	VERB
brainmatters-688	48	25	these	these	DET
brainmatters-688	48	26	obstacles	obstacle	NOUN
brainmatters-688	48	27	.	.	PUNCT
brainmatters-688	49	1	polymer	polymer	NOUN
brainmatters-688	49	2	-	-	PUNCT
brainmatters-688	49	3	based	base	VERB
brainmatters-688	49	4	materials	material	NOUN
brainmatters-688	49	5	,	,	PUNCT
brainmatters-688	49	6	including	include	VERB
brainmatters-688	49	7	hydrogels	hydrogel	NOUN
brainmatters-688	49	8	,	,	PUNCT
brainmatters-688	49	9	particles	particle	NOUN
brainmatters-688	49	10	,	,	PUNCT
brainmatters-688	49	11	and	and	CCONJ
brainmatters-688	49	12	fibers	fiber	NOUN
brainmatters-688	49	13	/	/	SYM
brainmatters-688	49	14	conduits	conduit	NOUN
brainmatters-688	49	15	,	,	PUNCT
brainmatters-688	49	16	are	be	AUX
brainmatters-688	49	17	implantable	implantable	ADJ
brainmatters-688	49	18	or	or	CCONJ
brainmatters-688	49	19	sometimes	sometimes	ADV
brainmatters-688	49	20	injectable	injectable	ADJ
brainmatters-688	49	21	;	;	PUNCT
brainmatters-688	49	22	they	they	PRON
brainmatters-688	49	23	can	can	AUX
brainmatters-688	49	24	prevent	prevent	VERB
brainmatters-688	49	25	detrimental	detrimental	ADJ
brainmatters-688	49	26	side	side	NOUN
brainmatters-688	49	27	effects	effect	NOUN
brainmatters-688	49	28	of	of	ADP
brainmatters-688	49	29	drugs	drug	NOUN
brainmatters-688	49	30	delivered	deliver	VERB
brainmatters-688	49	31	systemically	systemically	ADV
brainmatters-688	49	32	,	,	PUNCT
brainmatters-688	49	33	such	such	ADJ
brainmatters-688	49	34	as	as	ADP
brainmatters-688	49	35	a	a	DET
brainmatters-688	49	36	compromised	compromise	VERB
brainmatters-688	49	37	immune	immune	ADJ
brainmatters-688	49	38	system	system	NOUN
brainmatters-688	49	39	.	.	PUNCT
brainmatters-688	50	1	such	such	ADJ
brainmatters-688	50	2	biomaterials	biomaterial	NOUN
brainmatters-688	50	3	are	be	AUX
brainmatters-688	50	4	targeted	target	VERB
brainmatters-688	50	5	to	to	PART
brainmatters-688	50	6	provide	provide	VERB
brainmatters-688	50	7	structural	structural	ADJ
brainmatters-688	50	8	support	support	NOUN
brainmatters-688	50	9	to	to	ADP
brainmatters-688	50	10	regenerating	regenerate	VERB
brainmatters-688	50	11	axons	axon	NOUN
brainmatters-688	50	12	and	and	CCONJ
brainmatters-688	50	13	glia	glia	NOUN
brainmatters-688	50	14	migrating	migrating	NOUN
brainmatters-688	50	15	into	into	ADP
brainmatters-688	50	16	the	the	DET
brainmatters-688	50	17	injury	injury	NOUN
brainmatters-688	50	18	site	site	NOUN
brainmatters-688	50	19	.	.	PUNCT
brainmatters-688	51	1	they	they	PRON
brainmatters-688	51	2	also	also	ADV
brainmatters-688	51	3	aim	aim	VERB
brainmatters-688	51	4	to	to	PART
brainmatters-688	51	5	provide	provide	VERB
brainmatters-688	51	6	a	a	DET
brainmatters-688	51	7	similar	similar	ADJ
brainmatters-688	51	8	mechanical	mechanical	ADJ
brainmatters-688	51	9	and	and	CCONJ
brainmatters-688	51	10	biological	biological	ADJ
brainmatters-688	51	11	environment	environment	NOUN
brainmatters-688	51	12	as	as	ADP
brainmatters-688	51	13	those	those	PRON
brainmatters-688	51	14	of	of	ADP
brainmatters-688	51	15	the	the	DET
brainmatters-688	51	16	nerve	nerve	NOUN
brainmatters-688	51	17	tissue	tissue	NOUN
brainmatters-688	51	18	matrix	matrix	NOUN
brainmatters-688	51	19	and	and	CCONJ
brainmatters-688	51	20	degrade	degrade	VERB
brainmatters-688	51	21	over	over	ADP
brainmatters-688	51	22	time	time	NOUN
brainmatters-688	51	23	to	to	PART
brainmatters-688	51	24	be	be	AUX
brainmatters-688	51	25	replaced	replace	VERB
brainmatters-688	51	26	by	by	ADP
brainmatters-688	51	27	regenerating	regenerate	VERB
brainmatters-688	51	28	tissue	tissue	NOUN
brainmatters-688	51	29	.	.	PUNCT
brainmatters-688	52	1	for	for	ADP
brainmatters-688	52	2	instance	instance	NOUN
brainmatters-688	52	3	,	,	PUNCT
brainmatters-688	52	4	hydrogels	hydrogel	NOUN
brainmatters-688	52	5	are	be	AUX
brainmatters-688	52	6	injected	inject	VERB
brainmatters-688	52	7	into	into	ADP
brainmatters-688	52	8	the	the	DET
brainmatters-688	52	9	intrathecal	intrathecal	ADJ
brainmatters-688	52	10	space	space	NOUN
brainmatters-688	52	11	of	of	ADP
brainmatters-688	52	12	the	the	DET
brainmatters-688	52	13	spinal	spinal	NOUN
brainmatters-688	52	14	cord	cord	NOUN
brainmatters-688	52	15	,	,	PUNCT
brainmatters-688	52	16	most	most	ADV
brainmatters-688	52	17	commonly	commonly	ADV
brainmatters-688	52	18	in	in	ADP
brainmatters-688	52	19	treatments	treatment	NOUN
brainmatters-688	52	20	of	of	ADP
brainmatters-688	52	21	contusive	contusive	ADJ
brainmatters-688	52	22	sci	sci	PROPN
brainmatters-688	52	23	.	.	PROPN
brainmatters-688	53	1	for	for	ADP
brainmatters-688	53	2	an	an	DET
brainmatters-688	53	3	acute	acute	ADJ
brainmatters-688	53	4	injury	injury	NOUN
brainmatters-688	53	5	,	,	PUNCT
brainmatters-688	53	6	hydrogels	hydrogel	NOUN
brainmatters-688	53	7	are	be	AUX
brainmatters-688	53	8	injected	inject	VERB
brainmatters-688	53	9	onto	onto	ADP
brainmatters-688	53	10	the	the	DET
brainmatters-688	53	11	contusion	contusion	NOUN
brainmatters-688	53	12	injury	injury	NOUN
brainmatters-688	53	13	site	site	NOUN
brainmatters-688	53	14	,	,	PUNCT
brainmatters-688	53	15	and	and	CCONJ
brainmatters-688	53	16	solidified	solidify	VERB
brainmatters-688	53	17	gels	gel	NOUN
brainmatters-688	53	18	onto	onto	ADP
brainmatters-688	53	19	the	the	DET
brainmatters-688	53	20	hemisection	hemisection	NOUN
brainmatters-688	53	21	injury	injury	NOUN
brainmatters-688	53	22	site	site	NOUN
brainmatters-688	53	23	.	.	PUNCT
brainmatters-688	54	1	for	for	ADP
brainmatters-688	54	2	secondary	secondary	ADJ
brainmatters-688	54	3	injury	injury	NOUN
brainmatters-688	54	4	,	,	PUNCT
brainmatters-688	54	5	hydrogels	hydrogel	NOUN
brainmatters-688	54	6	incorporating	incorporate	VERB
brainmatters-688	54	7	particles	particle	NOUN
brainmatters-688	54	8	are	be	AUX
brainmatters-688	54	9	injected	inject	VERB
brainmatters-688	54	10	onto	onto	ADP
brainmatters-688	54	11	the	the	DET
brainmatters-688	54	12	contusion	contusion	NOUN
brainmatters-688	54	13	injury	injury	NOUN
brainmatters-688	54	14	site	site	NOUN
brainmatters-688	54	15	,	,	PUNCT
brainmatters-688	54	16	and	and	CCONJ
brainmatters-688	54	17	solidified	solidify	VERB
brainmatters-688	54	18	gels	gel	NOUN
brainmatters-688	54	19	with	with	ADP
brainmatters-688	54	20	particles	particle	NOUN
brainmatters-688	54	21	onto	onto	ADP
brainmatters-688	54	22	the	the	DET
brainmatters-688	54	23	hemisection	hemisection	NOUN
brainmatters-688	54	24	injury	injury	NOUN
brainmatters-688	54	25	site	site	NOUN
brainmatters-688	54	26	.	.	PUNCT
brainmatters-688	55	1	a	a	DET
brainmatters-688	55	2	small	small	ADJ
brainmatters-688	55	3	cavity	cavity	NOUN
brainmatters-688	55	4	grows	grow	VERB
brainmatters-688	55	5	within	within	ADP
brainmatters-688	55	6	the	the	DET
brainmatters-688	55	7	contusion	contusion	NOUN
brainmatters-688	55	8	injury	injury	NOUN
brainmatters-688	55	9	during	during	ADP
brainmatters-688	55	10	the	the	DET
brainmatters-688	55	11	proliferation	proliferation	NOUN
brainmatters-688	55	12	and	and	CCONJ
brainmatters-688	55	13	chronic	chronic	ADJ
brainmatters-688	55	14	injury	injury	NOUN
brainmatters-688	55	15	phases	phase	NOUN
brainmatters-688	55	16	.	.	PUNCT
brainmatters-688	56	1	fibers	fiber	NOUN
brainmatters-688	56	2	are	be	AUX
brainmatters-688	56	3	positioned	position	VERB
brainmatters-688	56	4	below	below	ADP
brainmatters-688	56	5	the	the	DET
brainmatters-688	56	6	dura	dura	NOUN
brainmatters-688	56	7	within	within	ADP
brainmatters-688	56	8	the	the	DET
brainmatters-688	56	9	contusion	contusion	NOUN
brainmatters-688	56	10	injury	injury	NOUN
brainmatters-688	56	11	space	space	NOUN
brainmatters-688	56	12	,	,	PUNCT
brainmatters-688	56	13	while	while	SCONJ
brainmatters-688	56	14	the	the	DET
brainmatters-688	56	15	conduit	conduit	NOUN
brainmatters-688	56	16	scaffolds	scaffold	VERB
brainmatters-688	56	17	within	within	ADP
brainmatters-688	56	18	the	the	DET
brainmatters-688	56	19	hemisection	hemisection	NOUN
brainmatters-688	56	20	injury	injury	NOUN
brainmatters-688	56	21	connect	connect	VERB
brainmatters-688	56	22	to	to	ADP
brainmatters-688	56	23	the	the	DET
brainmatters-688	56	24	healthy	healthy	ADJ
brainmatters-688	56	25	tissue	tissue	NOUN
brainmatters-688	56	26	.	.	PUNCT
brainmatters-688	57	1	in	in	ADP
brainmatters-688	57	2	a	a	DET
brainmatters-688	57	3	study	study	NOUN
brainmatters-688	57	4	conducted	conduct	VERB
brainmatters-688	57	5	in	in	ADP
brainmatters-688	57	6	1995	1995	NUM
brainmatters-688	57	7	,	,	PUNCT
brainmatters-688	57	8	arg	arg	NOUN
brainmatters-688	57	9	-	-	PUNCT
brainmatters-688	57	10	gly	gly	ADJ
brainmatters-688	57	11	-	-	PUNCT
brainmatters-688	57	12	asp	asp	NOUN
brainmatters-688	57	13	peptide	peptide	NOUN
brainmatters-688	57	14	-	-	PUNCT
brainmatters-688	57	15	functionalized	functionalize	VERB
brainmatters-688	57	16	phpma	phpma	NOUN
brainmatters-688	57	17	hydrogels	hydrogel	NOUN
brainmatters-688	57	18	promoted	promote	VERB
brainmatters-688	57	19	angiogenesis	angiogenesis	NOUN
brainmatters-688	57	20	and	and	CCONJ
brainmatters-688	57	21	extension	extension	NOUN
brainmatters-688	57	22	of	of	ADP
brainmatters-688	57	23	axons	axon	NOUN
brainmatters-688	57	24	and	and	CCONJ
brainmatters-688	57	25	glial	glial	ADJ
brainmatters-688	57	26	cells	cell	NOUN
brainmatters-688	57	27	(	(	PUNCT
brainmatters-688	57	28	woerly	woerly	ADV
brainmatters-688	57	29	et	et	PROPN
brainmatters-688	57	30	al	al	PROPN
brainmatters-688	57	31	.	.	PROPN
brainmatters-688	57	32	,	,	PUNCT
brainmatters-688	57	33	1995	1995	NUM
brainmatters-688	57	34	)	)	PUNCT
brainmatters-688	57	35	.	.	PUNCT
brainmatters-688	58	1	in	in	ADP
brainmatters-688	58	2	addition	addition	NOUN
brainmatters-688	58	3	,	,	PUNCT
brainmatters-688	58	4	agarose	agarose	NOUN
brainmatters-688	58	5	is	be	AUX
brainmatters-688	58	6	another	another	DET
brainmatters-688	58	7	injectable	injectable	ADJ
brainmatters-688	58	8	biodegradable	biodegradable	ADJ
brainmatters-688	58	9	material	material	NOUN
brainmatters-688	58	10	as	as	SCONJ
brainmatters-688	58	11	it	it	PRON
brainmatters-688	58	12	solidifies	solidify	VERB
brainmatters-688	58	13	following	follow	VERB
brainmatters-688	58	14	injection	injection	NOUN
brainmatters-688	58	15	according	accord	VERB
brainmatters-688	58	16	to	to	ADP
brainmatters-688	58	17	changes	change	NOUN
brainmatters-688	58	18	in	in	ADP
brainmatters-688	58	19	the	the	DET
brainmatters-688	58	20	environment	environment	NOUN
brainmatters-688	58	21	such	such	ADJ
brainmatters-688	58	22	as	as	ADP
brainmatters-688	58	23	temperature	temperature	NOUN
brainmatters-688	58	24	and	and	CCONJ
brainmatters-688	58	25	ph	ph	ADJ
brainmatters-688	58	26	.	.	PROPN
brainmatters-688	58	27	brain	brain	NOUN
brainmatters-688	58	28	-	-	PUNCT
brainmatters-688	58	29	derived	derive	VERB
brainmatters-688	58	30	neurotrophic	neurotrophic	ADJ
brainmatters-688	58	31	factors	factor	NOUN
brainmatters-688	58	32	(	(	PUNCT
brainmatters-688	58	33	bdnf)-formulated	bdnf)-formulated	ADJ
brainmatters-688	58	34	agarose	agarose	NOUN
brainmatters-688	58	35	can	can	AUX
brainmatters-688	58	36	solidify	solidify	VERB
brainmatters-688	58	37	when	when	SCONJ
brainmatters-688	58	38	cooled	cool	VERB
brainmatters-688	58	39	post	post	NOUN
brainmatters-688	58	40	-	-	NOUN
brainmatters-688	58	41	injection	injection	NOUN
brainmatters-688	58	42	;	;	PUNCT
brainmatters-688	58	43	nevertheless	nevertheless	ADV
brainmatters-688	58	44	,	,	PUNCT
brainmatters-688	58	45	the	the	DET
brainmatters-688	58	46	appropriate	appropriate	ADJ
brainmatters-688	58	47	mechanism	mechanism	NOUN
brainmatters-688	58	48	to	to	PART
brainmatters-688	58	49	cool	cool	VERB
brainmatters-688	58	50	the	the	DET
brainmatters-688	58	51	material	material	NOUN
brainmatters-688	58	52	in	in	ADP
brainmatters-688	58	53	situ	situ	NOUN
brainmatters-688	58	54	should	should	AUX
brainmatters-688	58	55	still	still	ADV
brainmatters-688	58	56	be	be	AUX
brainmatters-688	58	57	concerned	concern	VERB
brainmatters-688	58	58	(	(	PUNCT
brainmatters-688	58	59	nguyen	nguyen	PROPN
brainmatters-688	58	60	&	&	CCONJ
brainmatters-688	58	61	lee	lee	PROPN
brainmatters-688	58	62	,	,	PUNCT
brainmatters-688	58	63	2010	2010	NUM
brainmatters-688	58	64	)	)	PUNCT
brainmatters-688	58	65	.	.	PUNCT
brainmatters-688	59	1	regenerative	regenerative	ADJ
brainmatters-688	59	2	capability	capability	NOUN
brainmatters-688	59	3	of	of	ADP
brainmatters-688	59	4	biomaterials	biomaterial	NOUN
brainmatters-688	59	5	is	be	AUX
brainmatters-688	59	6	based	base	VERB
brainmatters-688	59	7	on	on	ADP
brainmatters-688	59	8	figure	figure	NOUN
brainmatters-688	59	9	3	3	NUM
brainmatters-688	59	10	.	.	PUNCT
brainmatters-688	59	11	mechanism	mechanism	NOUN
brainmatters-688	59	12	of	of	ADP
brainmatters-688	59	13	hydrogel	hydrogel	NOUN
brainmatters-688	59	14	-	-	PUNCT
brainmatters-688	59	15	induced	induce	VERB
brainmatters-688	59	16	neural	neural	ADJ
brainmatters-688	59	17	regeneration	regeneration	NOUN
brainmatters-688	59	18	(	(	PUNCT
brainmatters-688	59	19	liu	liu	PROPN
brainmatters-688	59	20	et	et	PROPN
brainmatters-688	59	21	al	al	PROPN
brainmatters-688	59	22	.	.	PROPN
brainmatters-688	59	23	,	,	PUNCT
brainmatters-688	59	24	2018	2018	NUM
brainmatters-688	59	25	)	)	PUNCT
brainmatters-688	59	26	.	.	PUNCT
brainmatters-688	60	1	the	the	DET
brainmatters-688	60	2	cell	cell	NOUN
brainmatters-688	60	3	grafts	graft	NOUN
brainmatters-688	60	4	and	and	CCONJ
brainmatters-688	60	5	neurotrophic	neurotrophic	ADJ
brainmatters-688	60	6	factors	factor	NOUN
brainmatters-688	60	7	are	be	AUX
brainmatters-688	60	8	injected	inject	VERB
brainmatters-688	60	9	via	via	ADP
brainmatters-688	60	10	a	a	DET
brainmatters-688	60	11	hydrogel	hydrogel	NOUN
brainmatters-688	60	12	into	into	ADP
brainmatters-688	60	13	the	the	DET
brainmatters-688	60	14	muscle	muscle	NOUN
brainmatters-688	60	15	scaffolding	scaffolding	NOUN
brainmatters-688	60	16	.	.	PUNCT
brainmatters-688	61	1	the	the	DET
brainmatters-688	61	2	integration	integration	NOUN
brainmatters-688	61	3	of	of	ADP
brainmatters-688	61	4	the	the	DET
brainmatters-688	61	5	cells	cell	NOUN
brainmatters-688	61	6	+	+	CCONJ
brainmatters-688	61	7	neurotrophic	neurotrophic	ADJ
brainmatters-688	61	8	factors	factor	NOUN
brainmatters-688	61	9	lead	lead	VERB
brainmatters-688	61	10	to	to	ADP
brainmatters-688	61	11	activation	activation	NOUN
brainmatters-688	61	12	of	of	ADP
brainmatters-688	61	13	astrocytes	astrocyte	NOUN
brainmatters-688	61	14	,	,	PUNCT
brainmatters-688	61	15	microglia	microglia	ADJ
brainmatters-688	61	16	,	,	PUNCT
brainmatters-688	61	17	and	and	CCONJ
brainmatters-688	61	18	a	a	DET
brainmatters-688	61	19	variety	variety	NOUN
brainmatters-688	61	20	of	of	ADP
brainmatters-688	61	21	other	other	ADJ
brainmatters-688	61	22	neurons	neuron	NOUN
brainmatters-688	61	23	that	that	PRON
brainmatters-688	61	24	are	be	AUX
brainmatters-688	61	25	involved	involve	VERB
brainmatters-688	61	26	with	with	ADP
brainmatters-688	61	27	the	the	DET
brainmatters-688	61	28	repair	repair	NOUN
brainmatters-688	61	29	mechanism	mechanism	NOUN
brainmatters-688	61	30	within	within	ADP
brainmatters-688	61	31	the	the	DET
brainmatters-688	61	32	tissue	tissue	NOUN
brainmatters-688	61	33	.	.	PUNCT
brainmatters-688	62	1	7	7	NUM
brainmatters-688	62	2	brain	brain	NOUN
brainmatters-688	62	3	matters	matter	NOUN
brainmatters-688	62	4	volume	volume	VERB
brainmatters-688	62	5	2	2	NUM
brainmatters-688	62	6	its	its	PRON
brainmatters-688	62	7	ability	ability	NOUN
brainmatters-688	62	8	to	to	PART
brainmatters-688	62	9	deliver	deliver	VERB
brainmatters-688	62	10	appropriate	appropriate	ADJ
brainmatters-688	62	11	growth	growth	NOUN
brainmatters-688	62	12	factors	factor	NOUN
brainmatters-688	62	13	or	or	CCONJ
brainmatters-688	62	14	critical	critical	ADJ
brainmatters-688	62	15	components	component	NOUN
brainmatters-688	62	16	of	of	ADP
brainmatters-688	62	17	the	the	DET
brainmatters-688	62	18	extracellular	extracellular	ADJ
brainmatters-688	62	19	matrix	matrix	NOUN
brainmatters-688	62	20	(	(	PUNCT
brainmatters-688	62	21	ecm	ecm	PROPN
brainmatters-688	62	22	)	)	PUNCT
brainmatters-688	62	23	,	,	PUNCT
brainmatters-688	62	24	bind	bind	VERB
brainmatters-688	62	25	the	the	DET
brainmatters-688	62	26	same	same	ADJ
brainmatters-688	62	27	receptor	receptor	NOUN
brainmatters-688	62	28	as	as	ADP
brainmatters-688	62	29	their	their	PRON
brainmatters-688	62	30	natural	natural	ADJ
brainmatters-688	62	31	counterpart	counterpart	NOUN
brainmatters-688	62	32	to	to	PART
brainmatters-688	62	33	promote	promote	VERB
brainmatters-688	62	34	cell	cell	NOUN
brainmatters-688	62	35	attachment	attachment	NOUN
brainmatters-688	62	36	,	,	PUNCT
brainmatters-688	62	37	spreading	spread	VERB
brainmatters-688	62	38	,	,	PUNCT
brainmatters-688	62	39	and	and	CCONJ
brainmatters-688	62	40	proliferation	proliferation	NOUN
brainmatters-688	62	41	.	.	PUNCT
brainmatters-688	63	1	these	these	DET
brainmatters-688	63	2	peptides	peptide	NOUN
brainmatters-688	63	3	,	,	PUNCT
brainmatters-688	63	4	such	such	ADJ
brainmatters-688	63	5	as	as	ADP
brainmatters-688	63	6	the	the	DET
brainmatters-688	63	7	most	most	ADV
brainmatters-688	63	8	common	common	ADJ
brainmatters-688	63	9	examples	example	NOUN
brainmatters-688	63	10	,	,	PUNCT
brainmatters-688	63	11	tripeptide	tripeptide	ADP
brainmatters-688	63	12	rgd	rgd	PROPN
brainmatters-688	63	13	and	and	CCONJ
brainmatters-688	63	14	multidomain	multidomain	PROPN
brainmatters-688	63	15	peptide	peptide	NOUN
brainmatters-688	63	16	(	(	PUNCT
brainmatters-688	63	17	mdp	mdp	PROPN
brainmatters-688	63	18	)	)	PUNCT
brainmatters-688	63	19	,	,	PUNCT
brainmatters-688	63	20	are	be	AUX
brainmatters-688	63	21	attached	attach	VERB
brainmatters-688	63	22	to	to	ADP
brainmatters-688	63	23	syringe	syringe	NOUN
brainmatters-688	63	24	-	-	PUNCT
brainmatters-688	63	25	deliverable	deliverable	ADJ
brainmatters-688	63	26	hydrogels	hydrogel	NOUN
brainmatters-688	63	27	and	and	CCONJ
brainmatters-688	63	28	are	be	AUX
brainmatters-688	63	29	subcutaneously	subcutaneously	ADV
brainmatters-688	63	30	implanted	implant	VERB
brainmatters-688	63	31	into	into	ADP
brainmatters-688	63	32	the	the	DET
brainmatters-688	63	33	injury	injury	NOUN
brainmatters-688	63	34	site	site	NOUN
brainmatters-688	63	35	to	to	PART
brainmatters-688	63	36	provoke	provoke	VERB
brainmatters-688	63	37	neurogenesis	neurogenesis	NOUN
brainmatters-688	63	38	and	and	CCONJ
brainmatters-688	63	39	angiogenesis	angiogenesis	NOUN
brainmatters-688	63	40	resulting	result	VERB
brainmatters-688	63	41	in	in	ADP
brainmatters-688	63	42	the	the	DET
brainmatters-688	63	43	dense	dense	ADJ
brainmatters-688	63	44	vascular	vascular	ADJ
brainmatters-688	63	45	network	network	NOUN
brainmatters-688	63	46	.	.	PUNCT
brainmatters-688	64	1	as	as	SCONJ
brainmatters-688	64	2	discussed	discuss	VERB
brainmatters-688	64	3	above	above	ADV
brainmatters-688	64	4	,	,	PUNCT
brainmatters-688	64	5	these	these	DET
brainmatters-688	64	6	biomaterials	biomaterial	NOUN
brainmatters-688	64	7	predictably	predictably	ADV
brainmatters-688	64	8	degrade	degrade	VERB
brainmatters-688	64	9	over	over	ADP
brainmatters-688	64	10	time	time	NOUN
brainmatters-688	64	11	and	and	CCONJ
brainmatters-688	64	12	replaced	replace	VERB
brainmatters-688	64	13	with	with	ADP
brainmatters-688	64	14	the	the	DET
brainmatters-688	64	15	regenerating	regenerate	VERB
brainmatters-688	64	16	cellular	cellular	ADJ
brainmatters-688	64	17	matrix	matrix	NOUN
brainmatters-688	64	18	.	.	PUNCT
brainmatters-688	65	1	one	one	NUM
brainmatters-688	65	2	of	of	ADP
brainmatters-688	65	3	the	the	DET
brainmatters-688	65	4	greatest	great	ADJ
brainmatters-688	65	5	concerns	concern	NOUN
brainmatters-688	65	6	in	in	ADP
brainmatters-688	65	7	this	this	DET
brainmatters-688	65	8	approach	approach	NOUN
brainmatters-688	65	9	is	be	AUX
brainmatters-688	65	10	the	the	DET
brainmatters-688	65	11	immune	immune	ADJ
brainmatters-688	65	12	response	response	NOUN
brainmatters-688	65	13	to	to	ADP
brainmatters-688	65	14	the	the	DET
brainmatters-688	65	15	implanted	implant	VERB
brainmatters-688	65	16	biomaterials	biomaterial	NOUN
brainmatters-688	65	17	.	.	PUNCT
brainmatters-688	66	1	injections	injection	NOUN
brainmatters-688	66	2	generally	generally	ADV
brainmatters-688	66	3	lead	lead	VERB
brainmatters-688	66	4	to	to	ADP
brainmatters-688	66	5	an	an	DET
brainmatters-688	66	6	acute	acute	ADJ
brainmatters-688	66	7	inflammatory	inflammatory	ADJ
brainmatters-688	66	8	response	response	NOUN
brainmatters-688	66	9	as	as	SCONJ
brainmatters-688	66	10	hydrogels	hydrogel	NOUN
brainmatters-688	66	11	are	be	AUX
brainmatters-688	66	12	frequently	frequently	ADV
brainmatters-688	66	13	recognized	recognize	VERB
brainmatters-688	66	14	as	as	ADP
brainmatters-688	66	15	foreign	foreign	ADJ
brainmatters-688	66	16	material	material	NOUN
brainmatters-688	66	17	(	(	PUNCT
brainmatters-688	66	18	moore	moore	PROPN
brainmatters-688	66	19	et	et	PROPN
brainmatters-688	66	20	al	al	PROPN
brainmatters-688	66	21	.	.	PROPN
brainmatters-688	66	22	,	,	PUNCT
brainmatters-688	66	23	2018	2018	NUM
brainmatters-688	66	24	)	)	PUNCT
brainmatters-688	66	25	.	.	PUNCT
brainmatters-688	67	1	several	several	ADJ
brainmatters-688	67	2	aspects	aspect	NOUN
brainmatters-688	67	3	such	such	ADJ
brainmatters-688	67	4	as	as	ADP
brainmatters-688	67	5	the	the	DET
brainmatters-688	67	6	local	local	ADJ
brainmatters-688	67	7	context	context	NOUN
brainmatters-688	67	8	of	of	ADP
brainmatters-688	67	9	biomaterials	biomaterial	NOUN
brainmatters-688	67	10	influence	influence	VERB
brainmatters-688	67	11	the	the	DET
brainmatters-688	67	12	innate	innate	ADJ
brainmatters-688	67	13	properties	property	NOUN
brainmatters-688	67	14	of	of	ADP
brainmatters-688	67	15	the	the	DET
brainmatters-688	67	16	implanted	implant	VERB
brainmatters-688	67	17	biomaterials	biomaterial	NOUN
brainmatters-688	67	18	that	that	PRON
brainmatters-688	67	19	form	form	VERB
brainmatters-688	67	20	the	the	DET
brainmatters-688	67	21	extent	extent	NOUN
brainmatters-688	67	22	of	of	ADP
brainmatters-688	67	23	the	the	DET
brainmatters-688	67	24	immune	immune	ADJ
brainmatters-688	67	25	response	response	NOUN
brainmatters-688	67	26	(	(	PUNCT
brainmatters-688	67	27	sadtler	sadtler	NOUN
brainmatters-688	67	28	et	et	PROPN
brainmatters-688	67	29	al	al	PROPN
brainmatters-688	67	30	.	.	PROPN
brainmatters-688	67	31	,	,	PUNCT
brainmatters-688	67	32	2016	2016	NUM
brainmatters-688	67	33	)	)	PUNCT
brainmatters-688	67	34	.	.	PUNCT
brainmatters-688	68	1	thus	thus	ADV
brainmatters-688	68	2	,	,	PUNCT
brainmatters-688	68	3	multiple	multiple	ADJ
brainmatters-688	68	4	approaches	approach	NOUN
brainmatters-688	68	5	are	be	AUX
brainmatters-688	68	6	being	be	AUX
brainmatters-688	68	7	discovered	discover	VERB
brainmatters-688	68	8	to	to	PART
brainmatters-688	68	9	minimize	minimize	VERB
brainmatters-688	68	10	the	the	DET
brainmatters-688	68	11	potentially	potentially	ADV
brainmatters-688	68	12	harmful	harmful	ADJ
brainmatters-688	68	13	immune	immune	ADJ
brainmatters-688	68	14	response	response	NOUN
brainmatters-688	68	15	in	in	ADP
brainmatters-688	68	16	treatments	treatment	NOUN
brainmatters-688	68	17	involving	involve	VERB
brainmatters-688	68	18	biomaterial	biomaterial	ADJ
brainmatters-688	68	19	injection	injection	NOUN
brainmatters-688	68	20	.	.	PUNCT
brainmatters-688	69	1	as	as	SCONJ
brainmatters-688	69	2	both	both	DET
brainmatters-688	69	3	approaches	approach	NOUN
brainmatters-688	69	4	,	,	PUNCT
brainmatters-688	69	5	drug	drug	NOUN
brainmatters-688	69	6	delivery	delivery	NOUN
brainmatters-688	69	7	via	via	ADP
brainmatters-688	69	8	nanoparticles	nanoparticle	NOUN
brainmatters-688	69	9	and	and	CCONJ
brainmatters-688	69	10	direct	direct	ADJ
brainmatters-688	69	11	injection	injection	NOUN
brainmatters-688	69	12	of	of	ADP
brainmatters-688	69	13	biomaterials	biomaterial	NOUN
brainmatters-688	69	14	,	,	PUNCT
brainmatters-688	69	15	have	have	VERB
brainmatters-688	69	16	distinct	distinct	ADJ
brainmatters-688	69	17	compatibility	compatibility	NOUN
brainmatters-688	69	18	in	in	ADP
brainmatters-688	69	19	treating	treat	VERB
brainmatters-688	69	20	different	different	ADJ
brainmatters-688	69	21	neuroregeneration	neuroregeneration	NOUN
brainmatters-688	69	22	-	-	PUNCT
brainmatters-688	69	23	related	relate	VERB
brainmatters-688	69	24	diseases	disease	NOUN
brainmatters-688	69	25	or	or	CCONJ
brainmatters-688	69	26	injuries	injury	NOUN
brainmatters-688	69	27	,	,	PUNCT
brainmatters-688	69	28	combining	combine	VERB
brainmatters-688	69	29	these	these	DET
brainmatters-688	69	30	techniques	technique	NOUN
brainmatters-688	69	31	can	can	AUX
brainmatters-688	69	32	be	be	AUX
brainmatters-688	69	33	a	a	DET
brainmatters-688	69	34	possible	possible	ADJ
brainmatters-688	69	35	solution	solution	NOUN
brainmatters-688	69	36	to	to	PART
brainmatters-688	69	37	overcome	overcome	VERB
brainmatters-688	69	38	inherent	inherent	ADJ
brainmatters-688	69	39	problems	problem	NOUN
brainmatters-688	69	40	in	in	ADP
brainmatters-688	69	41	these	these	DET
brainmatters-688	69	42	methods	method	NOUN
brainmatters-688	69	43	(	(	PUNCT
brainmatters-688	69	44	schmidt	schmidt	NOUN
brainmatters-688	69	45	&	&	CCONJ
brainmatters-688	69	46	leach	leach	NOUN
brainmatters-688	69	47	,	,	PUNCT
brainmatters-688	69	48	2003	2003	NUM
brainmatters-688	69	49	)	)	PUNCT
brainmatters-688	69	50	.	.	PUNCT
brainmatters-688	70	1	followed	follow	VERB
brainmatters-688	70	2	by	by	ADP
brainmatters-688	70	3	more	more	ADV
brainmatters-688	70	4	extensive	extensive	ADJ
brainmatters-688	70	5	research	research	NOUN
brainmatters-688	70	6	in	in	ADP
brainmatters-688	70	7	individual	individual	ADJ
brainmatters-688	70	8	techniques	technique	NOUN
brainmatters-688	70	9	,	,	PUNCT
brainmatters-688	70	10	an	an	DET
brainmatters-688	70	11	appropriate	appropriate	ADJ
brainmatters-688	70	12	combination	combination	NOUN
brainmatters-688	70	13	of	of	ADP
brainmatters-688	70	14	these	these	PRON
brainmatters-688	70	15	could	could	AUX
brainmatters-688	70	16	result	result	VERB
brainmatters-688	70	17	in	in	ADP
brainmatters-688	70	18	significant	significant	ADJ
brainmatters-688	70	19	improvements	improvement	NOUN
brainmatters-688	70	20	of	of	ADP
brainmatters-688	70	21	multiple	multiple	ADJ
brainmatters-688	70	22	neurological	neurological	ADJ
brainmatters-688	70	23	illnesses	illness	NOUN
brainmatters-688	70	24	by	by	ADP
brainmatters-688	70	25	inducing	induce	VERB
brainmatters-688	70	26	neural	neural	ADJ
brainmatters-688	70	27	regeneration	regeneration	NOUN
brainmatters-688	70	28	in	in	ADP
brainmatters-688	70	29	different	different	ADJ
brainmatters-688	70	30	situations	situation	NOUN
brainmatters-688	70	31	as	as	SCONJ
brainmatters-688	70	32	needed	need	VERB
brainmatters-688	70	33	.	.	PUNCT
brainmatters-688	71	1	references	reference	NOUN
brainmatters-688	71	2	adekoya	adekoya	VERB
brainmatters-688	71	3	,	,	PUNCT
brainmatters-688	71	4	n.	n.	PROPN
brainmatters-688	71	5	,	,	PUNCT
brainmatters-688	71	6	thurman	thurman	PROPN
brainmatters-688	71	7	,	,	PUNCT
brainmatters-688	71	8	d.	d.	PROPN
brainmatters-688	71	9	j.	j.	PROPN
brainmatters-688	71	10	,	,	PUNCT
brainmatters-688	71	11	webb	webb	PROPN
brainmatters-688	71	12	,	,	PUNCT
brainmatters-688	71	13	k.	k.	PROPN
brainmatters-688	71	14	w.	w.	PROPN
brainmatters-688	71	15	,	,	PUNCT
brainmatters-688	71	16	&	&	CCONJ
brainmatters-688	71	17	white	white	PROPN
brainmatters-688	71	18	,	,	PUNCT
brainmatters-688	71	19	d.	d.	PROPN
brainmatters-688	71	20	d.	d.	PROPN
brainmatters-688	71	21	(	(	PUNCT
brainmatters-688	71	22	2002	2002	NUM
brainmatters-688	71	23	)	)	PUNCT
brainmatters-688	71	24	.	.	PUNCT
brainmatters-688	72	1	surveillance	surveillance	NOUN
brainmatters-688	72	2	for	for	ADP
brainmatters-688	72	3	traumatic	traumatic	ADJ
brainmatters-688	72	4	brain	brain	NOUN
brainmatters-688	72	5	injury	injury	NOUN
brainmatters-688	72	6	deaths	death	NOUN
brainmatters-688	72	7	--	--	PUNCT
brainmatters-688	72	8	united	united	PROPN
brainmatters-688	72	9	states	states	PROPN
brainmatters-688	72	10	,	,	PUNCT
brainmatters-688	72	11	1989	1989	NUM
brainmatters-688	72	12	-	-	SYM
brainmatters-688	72	13	1998	1998	NUM
brainmatters-688	72	14	.	.	PUNCT
brainmatters-688	73	1	alzheimer	alzheimer	PROPN
brainmatters-688	73	2	’s	’s	PROPN
brainmatters-688	73	3	association	association	PROPN
brainmatters-688	73	4	.	.	PUNCT
brainmatters-688	74	1	(	(	PUNCT
brainmatters-688	74	2	2016	2016	NUM
brainmatters-688	74	3	)	)	PUNCT
brainmatters-688	74	4	.	.	PUNCT
brainmatters-688	75	1	2016	2016	NUM
brainmatters-688	75	2	alzheimer	alzheimer	PROPN
brainmatters-688	75	3	’s	’s	PART
brainmatters-688	75	4	disease	disease	NOUN
brainmatters-688	75	5	facts	fact	NOUN
brainmatters-688	75	6	and	and	CCONJ
brainmatters-688	75	7	figures	figure	NOUN
brainmatters-688	75	8	.	.	PUNCT
brainmatters-688	76	1	alzheimer	alzheimer	PROPN
brainmatters-688	76	2	’s	’s	PART
brainmatters-688	76	3	&	&	CCONJ
brainmatters-688	76	4	dementia	dementia	PROPN
brainmatters-688	76	5	,	,	PUNCT
brainmatters-688	76	6	12(4	12(4	NUM
brainmatters-688	76	7	)	)	PUNCT
brainmatters-688	76	8	,	,	PUNCT
brainmatters-688	76	9	459	459	NUM
brainmatters-688	76	10	-	-	SYM
brainmatters-688	76	11	509	509	NUM
brainmatters-688	76	12	.	.	PUNCT
brainmatters-688	76	13	blasi	blasi	NOUN
brainmatters-688	76	14	,	,	PUNCT
brainmatters-688	76	15	p.	p.	PROPN
brainmatters-688	76	16	,	,	PUNCT
brainmatters-688	76	17	giovagnoli	giovagnoli	ADJ
brainmatters-688	76	18	,	,	PUNCT
brainmatters-688	76	19	s.	s.	PROPN
brainmatters-688	76	20	,	,	PUNCT
brainmatters-688	76	21	schoubben	schoubben	PROPN
brainmatters-688	76	22	,	,	PUNCT
brainmatters-688	76	23	a.	a.	NOUN
brainmatters-688	76	24	,	,	PUNCT
brainmatters-688	76	25	ricci	ricci	PROPN
brainmatters-688	76	26	,	,	PUNCT
brainmatters-688	76	27	m.	m.	NOUN
brainmatters-688	76	28	,	,	PUNCT
brainmatters-688	76	29	&	&	CCONJ
brainmatters-688	76	30	rossi	rossi	PROPN
brainmatters-688	76	31	,	,	PUNCT
brainmatters-688	76	32	c.	c.	PROPN
brainmatters-688	76	33	(	(	PUNCT
brainmatters-688	76	34	2007	2007	NUM
brainmatters-688	76	35	)	)	PUNCT
brainmatters-688	76	36	.	.	PUNCT
brainmatters-688	77	1	solid	solid	ADJ
brainmatters-688	77	2	lipid	lipid	ADJ
brainmatters-688	77	3	nanoparticles	nanoparticle	NOUN
brainmatters-688	77	4	for	for	ADP
brainmatters-688	77	5	targeted	target	VERB
brainmatters-688	77	6	brain	brain	NOUN
brainmatters-688	77	7	drug	drug	NOUN
brainmatters-688	77	8	delivery	delivery	NOUN
brainmatters-688	77	9	.	.	PUNCT
brainmatters-688	78	1	advanced	advanced	ADJ
brainmatters-688	78	2	drug	drug	NOUN
brainmatters-688	78	3	delivery	delivery	NOUN
brainmatters-688	78	4	reviews	review	NOUN
brainmatters-688	78	5	,	,	PUNCT
brainmatters-688	78	6	59(6	59(6	NUM
brainmatters-688	78	7	)	)	PUNCT
brainmatters-688	78	8	,	,	PUNCT
brainmatters-688	78	9	454	454	NUM
brainmatters-688	78	10	-	-	SYM
brainmatters-688	78	11	477	477	NUM
brainmatters-688	78	12	.	.	PUNCT
brainmatters-688	79	1	bennett	bennett	PROPN
brainmatters-688	79	2	,	,	PUNCT
brainmatters-688	79	3	l.	l.	PROPN
brainmatters-688	79	4	,	,	PUNCT
brainmatters-688	79	5	yang	yang	PROPN
brainmatters-688	79	6	,	,	PUNCT
brainmatters-688	79	7	m.	m.	NOUN
brainmatters-688	79	8	,	,	PUNCT
brainmatters-688	79	9	enikolopov	enikolopov	PROPN
brainmatters-688	79	10	,	,	PUNCT
brainmatters-688	79	11	g.	g.	PROPN
brainmatters-688	79	12	,	,	PUNCT
brainmatters-688	79	13	&	&	CCONJ
brainmatters-688	79	14	iacovitti	iacovitti	PROPN
brainmatters-688	79	15	,	,	PUNCT
brainmatters-688	79	16	l.	l.	PROPN
brainmatters-688	79	17	(	(	PUNCT
brainmatters-688	79	18	2009	2009	NUM
brainmatters-688	79	19	)	)	PUNCT
brainmatters-688	79	20	.	.	PUNCT
brainmatters-688	80	1	circumventricular	circumventricular	ADJ
brainmatters-688	80	2	organs	organ	NOUN
brainmatters-688	80	3	:	:	PUNCT
brainmatters-688	80	4	a	a	DET
brainmatters-688	80	5	novel	novel	ADJ
brainmatters-688	80	6	site	site	NOUN
brainmatters-688	80	7	of	of	ADP
brainmatters-688	80	8	neural	neural	ADJ
brainmatters-688	80	9	stem	stem	NOUN
brainmatters-688	80	10	cells	cell	NOUN
brainmatters-688	80	11	in	in	ADP
brainmatters-688	80	12	the	the	DET
brainmatters-688	80	13	adult	adult	NOUN
brainmatters-688	80	14	brain	brain	NOUN
brainmatters-688	80	15	.	.	PUNCT
brainmatters-688	81	1	molecular	molecular	ADJ
brainmatters-688	81	2	and	and	CCONJ
brainmatters-688	81	3	cellular	cellular	ADJ
brainmatters-688	81	4	neuroscience	neuroscience	NOUN
brainmatters-688	81	5	,	,	PUNCT
brainmatters-688	81	6	41(3	41(3	NUM
brainmatters-688	81	7	)	)	PUNCT
brainmatters-688	81	8	,	,	PUNCT
brainmatters-688	81	9	337	337	NUM
brainmatters-688	81	10	-	-	SYM
brainmatters-688	81	11	347	347	NUM
brainmatters-688	81	12	.	.	PUNCT
brainmatters-688	82	1	chang	chang	PROPN
brainmatters-688	82	2	,	,	PUNCT
brainmatters-688	82	3	e.	e.	PROPN
brainmatters-688	82	4	h.	h.	PROPN
brainmatters-688	82	5	,	,	PUNCT
brainmatters-688	82	6	adorjan	adorjan	PROPN
brainmatters-688	82	7	,	,	PUNCT
brainmatters-688	82	8	i.	i.	NOUN
brainmatters-688	82	9	,	,	PUNCT
brainmatters-688	82	10	mundim	mundim	NOUN
brainmatters-688	82	11	,	,	PUNCT
brainmatters-688	82	12	m.	m.	NOUN
brainmatters-688	82	13	v.	v.	PROPN
brainmatters-688	82	14	,	,	PUNCT
brainmatters-688	82	15	sun	sun	PROPN
brainmatters-688	82	16	,	,	PUNCT
brainmatters-688	82	17	b.	b.	PROPN
brainmatters-688	82	18	,	,	PUNCT
brainmatters-688	82	19	dizon	dizon	PROPN
brainmatters-688	82	20	,	,	PUNCT
brainmatters-688	82	21	m.	m.	PROPN
brainmatters-688	82	22	l.	l.	PROPN
brainmatters-688	82	23	,	,	PUNCT
brainmatters-688	82	24	&	&	CCONJ
brainmatters-688	82	25	szele	szele	PROPN
brainmatters-688	82	26	,	,	PUNCT
brainmatters-688	82	27	f.	f.	PROPN
brainmatters-688	82	28	g.	g.	PROPN
brainmatters-688	82	29	(	(	PUNCT
brainmatters-688	82	30	2016	2016	NUM
brainmatters-688	82	31	)	)	PUNCT
brainmatters-688	82	32	.	.	PUNCT
brainmatters-688	83	1	traumatic	traumatic	ADJ
brainmatters-688	83	2	brain	brain	NOUN
brainmatters-688	83	3	injury	injury	NOUN
brainmatters-688	83	4	activation	activation	NOUN
brainmatters-688	83	5	of	of	ADP
brainmatters-688	83	6	the	the	DET
brainmatters-688	83	7	adult	adult	NOUN
brainmatters-688	83	8	subventricular	subventricular	ADJ
brainmatters-688	83	9	zone	zone	NOUN
brainmatters-688	83	10	neurogenic	neurogenic	ADJ
brainmatters-688	83	11	niche	niche	NOUN
brainmatters-688	83	12	.	.	PUNCT
brainmatters-688	84	1	frontiers	frontier	NOUN
brainmatters-688	84	2	in	in	ADP
brainmatters-688	84	3	neuroscience	neuroscience	NOUN
brainmatters-688	84	4	,	,	PUNCT
brainmatters-688	84	5	10	10	NUM
brainmatters-688	84	6	,	,	PUNCT
brainmatters-688	84	7	332	332	NUM
brainmatters-688	84	8	.	.	PUNCT
brainmatters-688	84	9	cotman	cotman	NOUN
brainmatters-688	84	10	,	,	PUNCT
brainmatters-688	84	11	c.	c.	PROPN
brainmatters-688	84	12	w.	w.	PROPN
brainmatters-688	84	13	,	,	PUNCT
brainmatters-688	84	14	&	&	CCONJ
brainmatters-688	84	15	scheff	scheff	PROPN
brainmatters-688	84	16	,	,	PUNCT
brainmatters-688	84	17	s.	s.	PROPN
brainmatters-688	84	18	w.	w.	PROPN
brainmatters-688	84	19	(	(	PUNCT
brainmatters-688	84	20	1979	1979	NUM
brainmatters-688	84	21	)	)	PUNCT
brainmatters-688	84	22	.	.	PUNCT
brainmatters-688	85	1	compensatory	compensatory	ADJ
brainmatters-688	85	2	synapse	synapse	NOUN
brainmatters-688	85	3	growth	growth	NOUN
brainmatters-688	85	4	in	in	ADP
brainmatters-688	85	5	aged	aged	ADJ
brainmatters-688	85	6	animals	animal	NOUN
brainmatters-688	85	7	after	after	ADP
brainmatters-688	85	8	neuronal	neuronal	ADJ
brainmatters-688	85	9	death	death	NOUN
brainmatters-688	85	10	.	.	PUNCT
brainmatters-688	86	1	mechanisms	mechanism	NOUN
brainmatters-688	86	2	of	of	ADP
brainmatters-688	86	3	ageing	ageing	NOUN
brainmatters-688	86	4	and	and	CCONJ
brainmatters-688	86	5	development	development	NOUN
brainmatters-688	86	6	,	,	PUNCT
brainmatters-688	86	7	9(1	9(1	NUM
brainmatters-688	86	8	-	-	SYM
brainmatters-688	86	9	2	2	NUM
brainmatters-688	86	10	)	)	PUNCT
brainmatters-688	86	11	,	,	PUNCT
brainmatters-688	86	12	103	103	NUM
brainmatters-688	86	13	-	-	SYM
brainmatters-688	86	14	117	117	NUM
brainmatters-688	86	15	.	.	PUNCT
brainmatters-688	87	1	gerndt	gerndt	PROPN
brainmatters-688	87	2	,	,	PUNCT
brainmatters-688	87	3	s.	s.	PROPN
brainmatters-688	87	4	j.	j.	PROPN
brainmatters-688	87	5	,	,	PUNCT
brainmatters-688	87	6	rodriguez	rodriguez	PROPN
brainmatters-688	87	7	,	,	PUNCT
brainmatters-688	87	8	j.	j.	PROPN
brainmatters-688	87	9	l.	l.	PROPN
brainmatters-688	87	10	,	,	PUNCT
brainmatters-688	87	11	pawlik	pawlik	PROPN
brainmatters-688	87	12	,	,	PUNCT
brainmatters-688	87	13	j.	j.	PROPN
brainmatters-688	87	14	w.	w.	PROPN
brainmatters-688	87	15	,	,	PUNCT
brainmatters-688	87	16	taheri	taheri	PROPN
brainmatters-688	87	17	,	,	PUNCT
brainmatters-688	87	18	p.	p.	NOUN
brainmatters-688	87	19	a.	a.	NOUN
brainmatters-688	87	20	,	,	PUNCT
brainmatters-688	87	21	wahl	wahl	PROPN
brainmatters-688	87	22	,	,	PUNCT
brainmatters-688	87	23	w.	w.	PROPN
brainmatters-688	87	24	l.	l.	PROPN
brainmatters-688	87	25	,	,	PUNCT
brainmatters-688	87	26	micheals	micheal	NOUN
brainmatters-688	87	27	,	,	PUNCT
brainmatters-688	87	28	a.	a.	PROPN
brainmatters-688	87	29	j.	j.	PROPN
brainmatters-688	87	30	,	,	PUNCT
brainmatters-688	87	31	&	&	CCONJ
brainmatters-688	87	32	papadopoulos	papadopoulos	PROPN
brainmatters-688	87	33	,	,	PUNCT
brainmatters-688	87	34	s.	s.	PROPN
brainmatters-688	87	35	m.	m.	PROPN
brainmatters-688	87	36	(	(	PUNCT
brainmatters-688	87	37	1997	1997	NUM
brainmatters-688	87	38	)	)	PUNCT
brainmatters-688	87	39	.	.	PUNCT
brainmatters-688	88	1	consequences	consequence	NOUN
brainmatters-688	88	2	of	of	ADP
brainmatters-688	88	3	high	high	ADJ
brainmatters-688	88	4	-	-	PUNCT
brainmatters-688	88	5	dose	dose	NOUN
brainmatters-688	88	6	steroid	steroid	NOUN
brainmatters-688	88	7	therapy	therapy	NOUN
brainmatters-688	88	8	for	for	ADP
brainmatters-688	88	9	acute	acute	ADJ
brainmatters-688	88	10	spinal	spinal	PROPN
brainmatters-688	88	11	cord	cord	NOUN
brainmatters-688	88	12	injury	injury	NOUN
brainmatters-688	88	13	.	.	PUNCT
brainmatters-688	89	1	journal	journal	NOUN
brainmatters-688	89	2	of	of	ADP
brainmatters-688	89	3	trauma	trauma	NOUN
brainmatters-688	89	4	and	and	CCONJ
brainmatters-688	89	5	acute	acute	NOUN
brainmatters-688	89	6	care	care	NOUN
brainmatters-688	89	7	surgery	surgery	NOUN
brainmatters-688	89	8	,	,	PUNCT
brainmatters-688	89	9	42(2	42(2	NOUN
brainmatters-688	89	10	)	)	PUNCT
brainmatters-688	89	11	,	,	PUNCT
brainmatters-688	89	12	279	279	NUM
brainmatters-688	89	13	-	-	SYM
brainmatters-688	89	14	284	284	NUM
brainmatters-688	89	15	.	.	PUNCT
brainmatters-688	90	1	huang	huang	PROPN
brainmatters-688	90	2	,	,	PUNCT
brainmatters-688	90	3	l.	l.	PROPN
brainmatters-688	90	4	,	,	PUNCT
brainmatters-688	90	5	su	su	PROPN
brainmatters-688	90	6	,	,	PUNCT
brainmatters-688	90	7	t.	t.	PROPN
brainmatters-688	90	8	,	,	PUNCT
brainmatters-688	90	9	&	&	CCONJ
brainmatters-688	90	10	li	li	PROPN
brainmatters-688	90	11	,	,	PUNCT
brainmatters-688	90	12	x.	x.	PROPN
brainmatters-688	90	13	(	(	PUNCT
brainmatters-688	90	14	2013	2013	NUM
brainmatters-688	90	15	)	)	PUNCT
brainmatters-688	90	16	.	.	PUNCT
brainmatters-688	91	1	natural	natural	ADJ
brainmatters-688	91	2	products	product	NOUN
brainmatters-688	91	3	as	as	ADP
brainmatters-688	91	4	sources	source	NOUN
brainmatters-688	91	5	of	of	ADP
brainmatters-688	91	6	new	new	ADJ
brainmatters-688	91	7	lead	lead	NOUN
brainmatters-688	91	8	compounds	compound	NOUN
brainmatters-688	91	9	for	for	ADP
brainmatters-688	91	10	the	the	DET
brainmatters-688	91	11	treatment	treatment	NOUN
brainmatters-688	91	12	of	of	ADP
brainmatters-688	91	13	alzheimer	alzheimer	PROPN
brainmatters-688	91	14	’s	’s	PART
brainmatters-688	91	15	disease	disease	NOUN
brainmatters-688	91	16	.	.	PUNCT
brainmatters-688	92	1	current	current	ADJ
brainmatters-688	92	2	topics	topic	NOUN
brainmatters-688	92	3	in	in	ADP
brainmatters-688	92	4	medicinal	medicinal	ADJ
brainmatters-688	92	5	chemistry	chemistry	NOUN
brainmatters-688	92	6	,	,	PUNCT
brainmatters-688	92	7	13(15	13(15	NUM
brainmatters-688	92	8	)	)	PUNCT
brainmatters-688	92	9	,	,	PUNCT
brainmatters-688	92	10	1864	1864	NUM
brainmatters-688	92	11	-	-	SYM
brainmatters-688	92	12	1878	1878	NUM
brainmatters-688	92	13	.	.	PUNCT
brainmatters-688	93	1	kreuter	kreuter	NOUN
brainmatters-688	93	2	,	,	PUNCT
brainmatters-688	93	3	j.	j.	PROPN
brainmatters-688	93	4	(	(	PUNCT
brainmatters-688	93	5	2014	2014	NUM
brainmatters-688	93	6	)	)	PUNCT
brainmatters-688	93	7	.	.	PUNCT
brainmatters-688	94	1	colloidal	colloidal	NOUN
brainmatters-688	94	2	drug	drug	NOUN
brainmatters-688	94	3	delivery	delivery	NOUN
brainmatters-688	94	4	systems	system	NOUN
brainmatters-688	94	5	(	(	PUNCT
brainmatters-688	94	6	vol	vol	NOUN
brainmatters-688	94	7	.	.	PROPN
brainmatters-688	94	8	66	66	NUM
brainmatters-688	94	9	)	)	PUNCT
brainmatters-688	94	10	.	.	PUNCT
brainmatters-688	95	1	crc	crc	PROPN
brainmatters-688	95	2	press	press	PROPN
brainmatters-688	95	3	.	.	PUNCT
brainmatters-688	96	1	liu	liu	PROPN
brainmatters-688	96	2	,	,	PUNCT
brainmatters-688	96	3	s.	s.	PROPN
brainmatters-688	96	4	,	,	PUNCT
brainmatters-688	96	5	schackel	schackel	NOUN
brainmatters-688	96	6	,	,	PUNCT
brainmatters-688	96	7	t.	t.	PROPN
brainmatters-688	96	8	,	,	PUNCT
brainmatters-688	96	9	weidner	weidner	PROPN
brainmatters-688	96	10	,	,	PUNCT
brainmatters-688	96	11	n.	n.	NOUN
brainmatters-688	96	12	,	,	PUNCT
brainmatters-688	96	13	&	&	CCONJ
brainmatters-688	96	14	puttagunta	puttagunta	PROPN
brainmatters-688	96	15	,	,	PUNCT
brainmatters-688	96	16	r.	r.	PROPN
brainmatters-688	96	17	(	(	PUNCT
brainmatters-688	96	18	2018	2018	NUM
brainmatters-688	96	19	)	)	PUNCT
brainmatters-688	96	20	.	.	PUNCT
brainmatters-688	97	1	biomaterial	biomaterial	ADJ
brainmatters-688	97	2	-	-	PUNCT
brainmatters-688	97	3	supported	support	VERB
brainmatters-688	97	4	cell	cell	NOUN
brainmatters-688	97	5	transplantation	transplantation	NOUN
brainmatters-688	97	6	treatments	treatment	NOUN
brainmatters-688	97	7	for	for	ADP
brainmatters-688	97	8	spinal	spinal	ADJ
brainmatters-688	97	9	cord	cord	NOUN
brainmatters-688	97	10	injury	injury	NOUN
brainmatters-688	97	11	:	:	PUNCT
brainmatters-688	97	12	challenges	challenge	NOUN
brainmatters-688	97	13	and	and	CCONJ
brainmatters-688	97	14	perspectives	perspective	NOUN
brainmatters-688	97	15	.	.	PUNCT
brainmatters-688	98	1	frontiers	frontier	NOUN
brainmatters-688	98	2	in	in	ADP
brainmatters-688	98	3	cellular	cellular	ADJ
brainmatters-688	98	4	neuroscience	neuroscience	NOUN
brainmatters-688	98	5	,	,	PUNCT
brainmatters-688	98	6	11	11	NUM
brainmatters-688	98	7	,	,	PUNCT
brainmatters-688	98	8	430	430	NUM
brainmatters-688	98	9	.	.	PUNCT
brainmatters-688	99	1	long	long	ADV
brainmatters-688	99	2	,	,	PUNCT
brainmatters-688	99	3	w.	w.	PROPN
brainmatters-688	99	4	,	,	PUNCT
brainmatters-688	99	5	yi	yi	PROPN
brainmatters-688	99	6	,	,	PUNCT
brainmatters-688	99	7	y.	y.	PROPN
brainmatters-688	99	8	,	,	PUNCT
brainmatters-688	99	9	chen	chen	PROPN
brainmatters-688	99	10	,	,	PUNCT
brainmatters-688	99	11	s.	s.	PROPN
brainmatters-688	99	12	,	,	PUNCT
brainmatters-688	99	13	cao	cao	PROPN
brainmatters-688	99	14	,	,	PUNCT
brainmatters-688	99	15	q.	q.	PROPN
brainmatters-688	99	16	,	,	PUNCT
brainmatters-688	99	17	zhao	zhao	PROPN
brainmatters-688	99	18	,	,	PUNCT
brainmatters-688	99	19	w.	w.	PROPN
brainmatters-688	99	20	,	,	PUNCT
brainmatters-688	99	21	&	&	CCONJ
brainmatters-688	99	22	liu	liu	PROPN
brainmatters-688	99	23	,	,	PUNCT
brainmatters-688	99	24	q.	q.	PROPN
brainmatters-688	99	25	(	(	PUNCT
brainmatters-688	99	26	2017	2017	NUM
brainmatters-688	99	27	)	)	PUNCT
brainmatters-688	99	28	.	.	PUNCT
brainmatters-688	100	1	potential	potential	ADJ
brainmatters-688	100	2	new	new	ADJ
brainmatters-688	100	3	therapies	therapy	NOUN
brainmatters-688	100	4	for	for	ADP
brainmatters-688	100	5	pediatric	pediatric	ADJ
brainmatters-688	100	6	diffuse	diffuse	NOUN
brainmatters-688	100	7	intrinsic	intrinsic	ADJ
brainmatters-688	100	8	pontine	pontine	ADJ
brainmatters-688	100	9	glioma	glioma	NOUN
brainmatters-688	100	10	.	.	PUNCT
brainmatters-688	101	1	frontiers	frontier	NOUN
brainmatters-688	101	2	in	in	ADP
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brainmatters-688	101	4	,	,	PUNCT
brainmatters-688	101	5	8	8	NUM
brainmatters-688	101	6	,	,	PUNCT
brainmatters-688	101	7	495	495	NUM
brainmatters-688	101	8	.	.	PUNCT
brainmatters-688	102	1	moore	moore	PROPN
brainmatters-688	102	2	,	,	PUNCT
brainmatters-688	102	3	a.	a.	PROPN
brainmatters-688	102	4	n.	n.	PROPN
brainmatters-688	102	5	,	,	PUNCT
brainmatters-688	102	6	silva	silva	PROPN
brainmatters-688	102	7	,	,	PUNCT
brainmatters-688	102	8	t.	t.	PROPN
brainmatters-688	102	9	l.	l.	PROPN
brainmatters-688	102	10	l.	l.	PROPN
brainmatters-688	102	11	,	,	PUNCT
brainmatters-688	102	12	carrejo	carrejo	PROPN
brainmatters-688	102	13	,	,	PUNCT
brainmatters-688	102	14	n.	n.	PROPN
brainmatters-688	102	15	c.	c.	PROPN
brainmatters-688	102	16	,	,	PUNCT
brainmatters-688	102	17	marmolejo	marmolejo	PROPN
brainmatters-688	102	18	,	,	PUNCT
brainmatters-688	102	19	c.	c.	PROPN
brainmatters-688	102	20	a.	a.	PROPN
brainmatters-688	102	21	o.	o.	PROPN
brainmatters-688	102	22	,	,	PUNCT
brainmatters-688	102	23	li	li	PROPN
brainmatters-688	102	24	,	,	PUNCT
brainmatters-688	102	25	i.	i.	PROPN
brainmatters-688	102	26	c.	c.	PROPN
brainmatters-688	102	27	,	,	PUNCT
brainmatters-688	102	28	&	&	CCONJ
brainmatters-688	102	29	hartgerink	hartgerink	PROPN
brainmatters-688	102	30	,	,	PUNCT
brainmatters-688	102	31	j.	j.	PROPN
brainmatters-688	102	32	d.	d.	PROPN
brainmatters-688	102	33	(	(	PUNCT
brainmatters-688	102	34	2018	2018	NUM
brainmatters-688	102	35	)	)	PUNCT
brainmatters-688	102	36	.	.	PUNCT
brainmatters-688	103	1	nanofibrous	nanofibrous	ADJ
brainmatters-688	103	2	peptide	peptide	ADJ
brainmatters-688	103	3	hydrogel	hydrogel	NOUN
brainmatters-688	103	4	elicits	elicit	VERB
brainmatters-688	103	5	angiogenesis	angiogenesis	NOUN
brainmatters-688	103	6	and	and	CCONJ
brainmatters-688	103	7	neurogenesis	neurogenesis	NOUN
brainmatters-688	103	8	without	without	ADP
brainmatters-688	103	9	drugs	drug	NOUN
brainmatters-688	103	10	,	,	PUNCT
brainmatters-688	103	11	proteins	protein	NOUN
brainmatters-688	103	12	,	,	PUNCT
brainmatters-688	103	13	or	or	CCONJ
brainmatters-688	103	14	cells	cell	NOUN
brainmatters-688	103	15	.	.	PUNCT
brainmatters-688	104	1	biomaterials	biomaterial	NOUN
brainmatters-688	104	2	,	,	PUNCT
brainmatters-688	104	3	161	161	NUM
brainmatters-688	104	4	,	,	PUNCT
brainmatters-688	104	5	154	154	NUM
brainmatters-688	104	6	-	-	SYM
brainmatters-688	104	7	163	163	NUM
brainmatters-688	104	8	.	.	PUNCT
brainmatters-688	105	1	nguyen	nguyen	NOUN
brainmatters-688	105	2	,	,	PUNCT
brainmatters-688	105	3	m.	m.	PROPN
brainmatters-688	105	4	k.	k.	PROPN
brainmatters-688	105	5	,	,	PUNCT
brainmatters-688	105	6	&	&	CCONJ
brainmatters-688	105	7	lee	lee	PROPN
brainmatters-688	105	8	,	,	PUNCT
brainmatters-688	105	9	d.	d.	PROPN
brainmatters-688	105	10	s.	s.	PROPN
brainmatters-688	105	11	(	(	PUNCT
brainmatters-688	105	12	2010	2010	NUM
brainmatters-688	105	13	)	)	PUNCT
brainmatters-688	105	14	.	.	PUNCT
brainmatters-688	106	1	injectable	injectable	ADJ
brainmatters-688	106	2	biodegradable	biodegradable	ADJ
brainmatters-688	106	3	hydrogels	hydrogel	NOUN
brainmatters-688	106	4	.	.	PUNCT
brainmatters-688	107	1	macromolecular	macromolecular	PROPN
brainmatters-688	107	2	bioscience	bioscience	PROPN
brainmatters-688	107	3	,	,	PUNCT
brainmatters-688	107	4	10(6	10(6	PROPN
brainmatters-688	107	5	)	)	PUNCT
brainmatters-688	107	6	,	,	PUNCT
brainmatters-688	107	7	563	563	NUM
brainmatters-688	107	8	-	-	SYM
brainmatters-688	107	9	579	579	NUM
brainmatters-688	107	10	.	.	PUNCT
brainmatters-688	108	1	prang	prang	PROPN
brainmatters-688	108	2	,	,	PUNCT
brainmatters-688	108	3	p.	p.	PROPN
brainmatters-688	108	4	,	,	PUNCT
brainmatters-688	108	5	müller	müller	PROPN
brainmatters-688	108	6	,	,	PUNCT
brainmatters-688	108	7	r.	r.	PROPN
brainmatters-688	108	8	,	,	PUNCT
brainmatters-688	108	9	eljaouhari	eljaouhari	PROPN
brainmatters-688	108	10	,	,	PUNCT
brainmatters-688	108	11	a.	a.	NOUN
brainmatters-688	108	12	,	,	PUNCT
brainmatters-688	108	13	heckmann	heckmann	PROPN
brainmatters-688	108	14	,	,	PUNCT
brainmatters-688	108	15	k.	k.	PROPN
brainmatters-688	108	16	,	,	PUNCT
brainmatters-688	108	17	kunz	kunz	PROPN
brainmatters-688	108	18	,	,	PUNCT
brainmatters-688	108	19	w.	w.	PROPN
brainmatters-688	108	20	,	,	PUNCT
brainmatters-688	108	21	weber	weber	PROPN
brainmatters-688	108	22	,	,	PUNCT
brainmatters-688	108	23	t.	t.	PROPN
brainmatters-688	108	24	,	,	PUNCT
brainmatters-688	108	25	...	...	PUNCT
brainmatters-688	108	26	&	&	CCONJ
brainmatters-688	108	27	weidner	weidner	PROPN
brainmatters-688	108	28	,	,	PUNCT
brainmatters-688	108	29	n.	n.	PROPN
brainmatters-688	108	30	(	(	PUNCT
brainmatters-688	108	31	2006	2006	NUM
brainmatters-688	108	32	)	)	PUNCT
brainmatters-688	108	33	.	.	PUNCT
brainmatters-688	109	1	the	the	DET
brainmatters-688	109	2	promotion	promotion	NOUN
brainmatters-688	109	3	of	of	ADP
brainmatters-688	109	4	oriented	orient	VERB
brainmatters-688	109	5	axonal	axonal	ADJ
brainmatters-688	109	6	regrowth	regrowth	NOUN
brainmatters-688	109	7	in	in	ADP
brainmatters-688	109	8	the	the	DET
brainmatters-688	109	9	injured	injure	VERB
brainmatters-688	109	10	spinal	spinal	NOUN
brainmatters-688	109	11	cord	cord	NOUN
brainmatters-688	109	12	by	by	ADP
brainmatters-688	109	13	alginate	alginate	NOUN
brainmatters-688	109	14	-	-	PUNCT
brainmatters-688	109	15	based	base	VERB
brainmatters-688	109	16	anisotropic	anisotropic	NOUN
brainmatters-688	109	17	capillary	capillary	ADJ
brainmatters-688	109	18	hydrogels	hydrogel	NOUN
brainmatters-688	109	19	.	.	PUNCT
brainmatters-688	110	1	biomaterials	biomaterial	NOUN
brainmatters-688	110	2	,	,	PUNCT
brainmatters-688	110	3	27(19	27(19	NUM
brainmatters-688	110	4	)	)	PUNCT
brainmatters-688	110	5	,	,	PUNCT
brainmatters-688	110	6	3560	3560	NUM
brainmatters-688	110	7	-	-	SYM
brainmatters-688	110	8	3569	3569	NUM
brainmatters-688	110	9	.	.	PUNCT
brainmatters-688	111	1	sadtler	sadtler	NOUN
brainmatters-688	111	2	,	,	PUNCT
brainmatters-688	111	3	k.	k.	PROPN
brainmatters-688	111	4	,	,	PUNCT
brainmatters-688	111	5	singh	singh	PROPN
brainmatters-688	111	6	,	,	PUNCT
brainmatters-688	111	7	a.	a.	NOUN
brainmatters-688	111	8	,	,	PUNCT
brainmatters-688	111	9	wolf	wolf	NOUN
brainmatters-688	111	10	,	,	PUNCT
brainmatters-688	111	11	m.	m.	NOUN
brainmatters-688	111	12	t.	t.	PROPN
brainmatters-688	111	13	,	,	PUNCT
brainmatters-688	111	14	wang	wang	PROPN
brainmatters-688	111	15	,	,	PUNCT
brainmatters-688	111	16	x.	x.	PROPN
brainmatters-688	111	17	,	,	PUNCT
brainmatters-688	111	18	pardoll	pardoll	PROPN
brainmatters-688	111	19	,	,	PUNCT
brainmatters-688	111	20	d.	d.	PROPN
brainmatters-688	111	21	m.	m.	PROPN
brainmatters-688	111	22	,	,	PUNCT
brainmatters-688	111	23	&	&	CCONJ
brainmatters-688	111	24	elisseeff	elisseeff	PROPN
brainmatters-688	111	25	,	,	PUNCT
brainmatters-688	111	26	j.	j.	PROPN
brainmatters-688	111	27	h.	h.	PROPN
brainmatters-688	111	28	(	(	PUNCT
brainmatters-688	111	29	2016	2016	NUM
brainmatters-688	111	30	)	)	PUNCT
brainmatters-688	111	31	.	.	PUNCT
brainmatters-688	112	1	design	design	NOUN
brainmatters-688	112	2	,	,	PUNCT
brainmatters-688	112	3	clinical	clinical	ADJ
brainmatters-688	112	4	translation	translation	NOUN
brainmatters-688	112	5	and	and	CCONJ
brainmatters-688	112	6	immunological	immunological	ADJ
brainmatters-688	112	7	response	response	NOUN
brainmatters-688	112	8	of	of	ADP
brainmatters-688	112	9	biomaterials	biomaterial	NOUN
brainmatters-688	112	10	in	in	ADP
brainmatters-688	112	11	regenerative	regenerative	ADJ
brainmatters-688	112	12	medicine	medicine	NOUN
brainmatters-688	112	13	.	.	PUNCT
brainmatters-688	113	1	nature	nature	NOUN
brainmatters-688	113	2	reviews	review	VERB
brainmatters-688	113	3	materials	material	NOUN
brainmatters-688	113	4	,	,	PUNCT
brainmatters-688	113	5	1(7	1(7	NUM
brainmatters-688	113	6	)	)	PUNCT
brainmatters-688	113	7	,	,	PUNCT
brainmatters-688	113	8	16040	16040	NUM
brainmatters-688	113	9	.	.	PUNCT
brainmatters-688	114	1	saraiva	saraiva	PROPN
brainmatters-688	114	2	,	,	PUNCT
brainmatters-688	114	3	c.	c.	PROPN
brainmatters-688	114	4	,	,	PUNCT
brainmatters-688	114	5	praça	praça	PROPN
brainmatters-688	114	6	,	,	PUNCT
brainmatters-688	114	7	c.	c.	PROPN
brainmatters-688	114	8	,	,	PUNCT
brainmatters-688	114	9	ferreira	ferreira	PROPN
brainmatters-688	114	10	,	,	PUNCT
brainmatters-688	114	11	r.	r.	PROPN
brainmatters-688	114	12	,	,	PUNCT
brainmatters-688	114	13	santos	santos	PROPN
brainmatters-688	114	14	,	,	PUNCT
brainmatters-688	114	15	t.	t.	PROPN
brainmatters-688	114	16	,	,	PUNCT
brainmatters-688	114	17	ferreira	ferreira	PROPN
brainmatters-688	114	18	,	,	PUNCT
brainmatters-688	114	19	l.	l.	PROPN
brainmatters-688	114	20	,	,	PUNCT
brainmatters-688	114	21	&	&	CCONJ
brainmatters-688	114	22	bernardino	bernardino	PROPN
brainmatters-688	114	23	,	,	PUNCT
brainmatters-688	114	24	l.	l.	PROPN
brainmatters-688	114	25	(	(	PUNCT
brainmatters-688	114	26	2016	2016	NUM
brainmatters-688	114	27	)	)	PUNCT
brainmatters-688	114	28	.	.	PUNCT
brainmatters-688	115	1	nanoparticle	nanoparticle	NOUN
brainmatters-688	115	2	-	-	PUNCT
brainmatters-688	115	3	mediated	mediate	VERB
brainmatters-688	115	4	brain	brain	NOUN
brainmatters-688	115	5	drug	drug	NOUN
brainmatters-688	115	6	delivery	delivery	NOUN
brainmatters-688	115	7	:	:	PUNCT
brainmatters-688	115	8	overcoming	overcome	VERB
brainmatters-688	115	9	blood	blood	NOUN
brainmatters-688	115	10	–	–	PUNCT
brainmatters-688	115	11	brain	brain	NOUN
brainmatters-688	115	12	barrier	barrier	NOUN
brainmatters-688	115	13	to	to	PART
brainmatters-688	115	14	treat	treat	VERB
brainmatters-688	115	15	neurodegenerative	neurodegenerative	ADJ
brainmatters-688	115	16	diseases	disease	NOUN
brainmatters-688	115	17	.	.	PUNCT
brainmatters-688	116	1	journal	journal	NOUN
brainmatters-688	116	2	of	of	ADP
brainmatters-688	116	3	controlled	control	VERB
brainmatters-688	116	4	release	release	NOUN
brainmatters-688	116	5	,	,	PUNCT
brainmatters-688	116	6	235	235	NUM
brainmatters-688	116	7	,	,	PUNCT
brainmatters-688	116	8	34	34	NUM
brainmatters-688	116	9	-	-	SYM
brainmatters-688	116	10	47	47	NUM
brainmatters-688	116	11	.	.	PUNCT
brainmatters-688	117	1	schmidt	schmidt	PROPN
brainmatters-688	117	2	,	,	PUNCT
brainmatters-688	117	3	c.	c.	PROPN
brainmatters-688	117	4	e.	e.	PROPN
brainmatters-688	117	5	,	,	PUNCT
brainmatters-688	117	6	&	&	CCONJ
brainmatters-688	117	7	leach	leach	NOUN
brainmatters-688	117	8	,	,	PUNCT
brainmatters-688	117	9	j.	j.	PROPN
brainmatters-688	117	10	b.	b.	PROPN
brainmatters-688	117	11	(	(	PUNCT
brainmatters-688	117	12	2003	2003	NUM
brainmatters-688	117	13	)	)	PUNCT
brainmatters-688	117	14	.	.	PUNCT
brainmatters-688	118	1	neural	neural	ADJ
brainmatters-688	118	2	tissue	tissue	NOUN
brainmatters-688	118	3	engineering	engineering	NOUN
brainmatters-688	118	4	:	:	PUNCT
brainmatters-688	118	5	strategies	strategy	NOUN
brainmatters-688	118	6	for	for	ADP
brainmatters-688	118	7	repair	repair	NOUN
brainmatters-688	118	8	and	and	CCONJ
brainmatters-688	118	9	regeneration	regeneration	NOUN
brainmatters-688	118	10	.	.	PUNCT
brainmatters-688	119	1	annual	annual	ADJ
brainmatters-688	119	2	review	review	NOUN
brainmatters-688	119	3	of	of	ADP
brainmatters-688	119	4	biomedical	biomedical	ADJ
brainmatters-688	119	5	engineering	engineering	NOUN
brainmatters-688	119	6	,	,	PUNCT
brainmatters-688	119	7	5(1	5(1	NUM
brainmatters-688	119	8	)	)	PUNCT
brainmatters-688	119	9	,	,	PUNCT
brainmatters-688	119	10	293	293	NUM
brainmatters-688	119	11	-	-	SYM
brainmatters-688	119	12	347	347	NUM
brainmatters-688	119	13	.	.	PUNCT
brainmatters-688	120	1	schwab	schwab	PROPN
brainmatters-688	120	2	,	,	PUNCT
brainmatters-688	120	3	m.	m.	PROPN
brainmatters-688	120	4	e.	e.	PROPN
brainmatters-688	120	5	(	(	PUNCT
brainmatters-688	120	6	2002	2002	NUM
brainmatters-688	120	7	)	)	PUNCT
brainmatters-688	120	8	.	.	PUNCT
brainmatters-688	121	1	repairing	repair	VERB
brainmatters-688	121	2	the	the	DET
brainmatters-688	121	3	injured	injure	VERB
brainmatters-688	121	4	spinal	spinal	NOUN
brainmatters-688	121	5	cord	cord	NOUN
brainmatters-688	121	6	.	.	PUNCT
brainmatters-688	122	1	science	science	NOUN
brainmatters-688	122	2	,	,	PUNCT
brainmatters-688	122	3	295(5557	295(5557	NUM
brainmatters-688	122	4	)	)	PUNCT
brainmatters-688	122	5	,	,	PUNCT
brainmatters-688	122	6	10291031	10291031	NUM
brainmatters-688	122	7	.	.	PUNCT
brainmatters-688	123	1	stabenfeldt	stabenfeldt	PROPN
brainmatters-688	123	2	,	,	PUNCT
brainmatters-688	123	3	s.	s.	PROPN
brainmatters-688	123	4	e.	e.	PROPN
brainmatters-688	123	5	,	,	PUNCT
brainmatters-688	123	6	garcía	garcía	PROPN
brainmatters-688	123	7	,	,	PUNCT
brainmatters-688	123	8	a.	a.	PROPN
brainmatters-688	123	9	j.	j.	PROPN
brainmatters-688	123	10	,	,	PUNCT
brainmatters-688	123	11	&	&	CCONJ
brainmatters-688	123	12	laplaca	laplaca	PROPN
brainmatters-688	123	13	,	,	PUNCT
brainmatters-688	123	14	m.	m.	NOUN
brainmatters-688	123	15	c.	c.	PROPN
brainmatters-688	123	16	(	(	PUNCT
brainmatters-688	123	17	2006	2006	NUM
brainmatters-688	123	18	)	)	PUNCT
brainmatters-688	123	19	.	.	PUNCT
brainmatters-688	124	1	thermoreversible	thermoreversible	ADJ
brainmatters-688	124	2	laminin‐functionalized	laminin‐functionalized	ADJ
brainmatters-688	124	3	hydrogel	hydrogel	NOUN
brainmatters-688	124	4	for	for	ADP
brainmatters-688	124	5	neural	neural	ADJ
brainmatters-688	124	6	tissue	tissue	NOUN
brainmatters-688	124	7	engineering	engineering	NOUN
brainmatters-688	124	8	.	.	PUNCT
brainmatters-688	125	1	journal	journal	PROPN
brainmatters-688	125	2	of	of	ADP
brainmatters-688	125	3	biomedical	biomedical	ADJ
brainmatters-688	125	4	materials	material	NOUN
brainmatters-688	125	5	research	research	NOUN
brainmatters-688	125	6	part	part	NOUN
brainmatters-688	125	7	a	a	PRON
brainmatters-688	125	8	:	:	PUNCT
brainmatters-688	125	9	an	an	DET
brainmatters-688	125	10	official	official	ADJ
brainmatters-688	125	11	journal	journal	NOUN
brainmatters-688	125	12	of	of	ADP
brainmatters-688	125	13	the	the	DET
brainmatters-688	125	14	society	society	NOUN
brainmatters-688	125	15	for	for	ADP
brainmatters-688	125	16	biomaterials	biomaterial	NOUN
brainmatters-688	125	17	,	,	PUNCT
brainmatters-688	125	18	the	the	DET
brainmatters-688	125	19	japanese	japanese	ADJ
brainmatters-688	125	20	society	society	NOUN
brainmatters-688	125	21	for	for	ADP
brainmatters-688	125	22	biomaterials	biomaterial	NOUN
brainmatters-688	125	23	,	,	PUNCT
brainmatters-688	125	24	and	and	CCONJ
brainmatters-688	125	25	the	the	DET
brainmatters-688	125	26	australian	australian	ADJ
brainmatters-688	125	27	society	society	NOUN
brainmatters-688	125	28	for	for	ADP
brainmatters-688	125	29	biomaterials	biomaterial	NOUN
brainmatters-688	125	30	and	and	CCONJ
brainmatters-688	125	31	the	the	DET
brainmatters-688	125	32	korean	korean	ADJ
brainmatters-688	125	33	society	society	NOUN
brainmatters-688	125	34	for	for	ADP
brainmatters-688	125	35	biomaterials	biomaterial	NOUN
brainmatters-688	125	36	,	,	PUNCT
brainmatters-688	125	37	77(4	77(4	NUM
brainmatters-688	125	38	)	)	PUNCT
brainmatters-688	125	39	,	,	PUNCT
brainmatters-688	125	40	718	718	NUM
brainmatters-688	125	41	-	-	SYM
brainmatters-688	125	42	725	725	NUM
brainmatters-688	125	43	.	.	PUNCT
brainmatters-688	125	44	tröster	tröster	NOUN
brainmatters-688	125	45	,	,	PUNCT
brainmatters-688	125	46	s.	s.	PROPN
brainmatters-688	125	47	d.	d.	PROPN
brainmatters-688	125	48	,	,	PUNCT
brainmatters-688	125	49	&	&	CCONJ
brainmatters-688	125	50	kreuter	kreuter	PROPN
brainmatters-688	125	51	,	,	PUNCT
brainmatters-688	125	52	j.	j.	PROPN
brainmatters-688	125	53	(	(	PUNCT
brainmatters-688	125	54	1988	1988	NUM
brainmatters-688	125	55	)	)	PUNCT
brainmatters-688	125	56	.	.	PUNCT
brainmatters-688	126	1	contact	contact	NOUN
brainmatters-688	126	2	angles	angle	NOUN
brainmatters-688	126	3	of	of	ADP
brainmatters-688	126	4	surfactants	surfactant	NOUN
brainmatters-688	126	5	with	with	ADP
brainmatters-688	126	6	a	a	DET
brainmatters-688	126	7	potential	potential	NOUN
brainmatters-688	126	8	to	to	PART
brainmatters-688	126	9	alter	alter	VERB
brainmatters-688	126	10	the	the	DET
brainmatters-688	126	11	body	body	NOUN
brainmatters-688	126	12	distribution	distribution	NOUN
brainmatters-688	126	13	of	of	ADP
brainmatters-688	126	14	colloidal	colloidal	NOUN
brainmatters-688	126	15	drug	drug	NOUN
brainmatters-688	126	16	carriers	carrier	NOUN
brainmatters-688	126	17	on	on	ADP
brainmatters-688	126	18	poly	poly	ADJ
brainmatters-688	126	19	(	(	PUNCT
brainmatters-688	126	20	methyl	methyl	NOUN
brainmatters-688	126	21	methacrylate	methacrylate	NOUN
brainmatters-688	126	22	)	)	PUNCT
brainmatters-688	126	23	surfaces	surface	NOUN
brainmatters-688	126	24	.	.	PUNCT
brainmatters-688	127	1	international	international	ADJ
brainmatters-688	127	2	journal	journal	PROPN
brainmatters-688	127	3	of	of	ADP
brainmatters-688	127	4	pharmaceutics	pharmaceutic	NOUN
brainmatters-688	127	5	,	,	PUNCT
brainmatters-688	127	6	45(1	45(1	NOUN
brainmatters-688	127	7	-	-	PUNCT
brainmatters-688	127	8	2	2	NUM
brainmatters-688	127	9	)	)	PUNCT
brainmatters-688	127	10	,	,	PUNCT
brainmatters-688	127	11	91	91	NUM
brainmatters-688	127	12	-	-	SYM
brainmatters-688	127	13	100	100	NUM
brainmatters-688	127	14	.	.	PUNCT
brainmatters-688	128	1	woerly	woerly	ADV
brainmatters-688	128	2	,	,	PUNCT
brainmatters-688	128	3	s.	s.	PROPN
brainmatters-688	128	4	,	,	PUNCT
brainmatters-688	128	5	laroche	laroche	PROPN
brainmatters-688	128	6	,	,	PUNCT
brainmatters-688	128	7	g.	g.	PROPN
brainmatters-688	128	8	,	,	PUNCT
brainmatters-688	128	9	marchand	marchand	PROPN
brainmatters-688	128	10	,	,	PUNCT
brainmatters-688	128	11	r.	r.	PROPN
brainmatters-688	128	12	,	,	PUNCT
brainmatters-688	128	13	pato	pato	PROPN
brainmatters-688	128	14	,	,	PUNCT
brainmatters-688	128	15	j.	j.	PROPN
brainmatters-688	128	16	,	,	PUNCT
brainmatters-688	128	17	subr	subr	PROPN
brainmatters-688	128	18	,	,	PUNCT
brainmatters-688	128	19	v.	v.	ADV
brainmatters-688	128	20	,	,	PUNCT
brainmatters-688	128	21	&	&	CCONJ
brainmatters-688	128	22	ulbrich	ulbrich	PROPN
brainmatters-688	128	23	,	,	PUNCT
brainmatters-688	128	24	k.	k.	PROPN
brainmatters-688	128	25	(	(	PUNCT
brainmatters-688	128	26	1995	1995	NUM
brainmatters-688	128	27	)	)	PUNCT
brainmatters-688	128	28	.	.	PUNCT
brainmatters-688	129	1	intracerebral	intracerebral	ADJ
brainmatters-688	129	2	implantation	implantation	NOUN
brainmatters-688	129	3	of	of	ADP
brainmatters-688	129	4	hydrogel	hydrogel	NOUN
brainmatters-688	129	5	-	-	PUNCT
brainmatters-688	129	6	coupled	couple	VERB
brainmatters-688	129	7	adhesion	adhesion	NOUN
brainmatters-688	129	8	peptides	peptide	NOUN
brainmatters-688	129	9	:	:	PUNCT
brainmatters-688	129	10	tissue	tissue	NOUN
brainmatters-688	129	11	reaction	reaction	NOUN
brainmatters-688	129	12	.	.	PUNCT
brainmatters-688	130	1	neural	neural	ADJ
brainmatters-688	130	2	plasticity	plasticity	NOUN
brainmatters-688	130	3	,	,	PUNCT
brainmatters-688	130	4	5(4	5(4	NUM
brainmatters-688	130	5	)	)	PUNCT
brainmatters-688	130	6	,	,	PUNCT
brainmatters-688	130	7	245	245	NUM
brainmatters-688	130	8	-	-	SYM
brainmatters-688	130	9	255	255	NUM
brainmatters-688	130	10	.	.	PUNCT
brainmatters-688	131	1	yemisci	yemisci	PROPN
brainmatters-688	131	2	,	,	PUNCT
brainmatters-688	131	3	m.	m.	NOUN
brainmatters-688	131	4	,	,	PUNCT
brainmatters-688	131	5	caban	caban	PROPN
brainmatters-688	131	6	,	,	PUNCT
brainmatters-688	131	7	s.	s.	PROPN
brainmatters-688	131	8	,	,	PUNCT
brainmatters-688	131	9	gursoy	gursoy	NOUN
brainmatters-688	131	10	-	-	PUNCT
brainmatters-688	131	11	ozdemir	ozdemir	NOUN
brainmatters-688	131	12	,	,	PUNCT
brainmatters-688	131	13	y.	y.	PROPN
brainmatters-688	131	14	,	,	PUNCT
brainmatters-688	131	15	lule	lule	PROPN
brainmatters-688	131	16	,	,	PUNCT
brainmatters-688	131	17	s.	s.	PROPN
brainmatters-688	131	18	,	,	PUNCT
brainmatters-688	131	19	novoa	novoa	NOUN
brainmatters-688	131	20	-	-	PUNCT
brainmatters-688	131	21	carballal	carballal	PROPN
brainmatters-688	131	22	,	,	PUNCT
brainmatters-688	131	23	r.	r.	PROPN
brainmatters-688	131	24	,	,	PUNCT
brainmatters-688	131	25	riguera	riguera	PROPN
brainmatters-688	131	26	,	,	PUNCT
brainmatters-688	131	27	r.	r.	PROPN
brainmatters-688	131	28	,	,	PUNCT
brainmatters-688	131	29	...	...	PUNCT
brainmatters-688	131	30	&	&	CCONJ
brainmatters-688	131	31	dalkara	dalkara	ADJ
brainmatters-688	131	32	,	,	PUNCT
brainmatters-688	131	33	t.	t.	PROPN
brainmatters-688	131	34	(	(	PUNCT
brainmatters-688	131	35	2015	2015	NUM
brainmatters-688	131	36	)	)	PUNCT
brainmatters-688	131	37	.	.	PUNCT
brainmatters-688	132	1	systemically	systemically	ADV
brainmatters-688	132	2	administered	administer	VERB
brainmatters-688	132	3	brain	brain	NOUN
brainmatters-688	132	4	-	-	PUNCT
brainmatters-688	132	5	targeted	target	VERB
brainmatters-688	132	6	nanoparticles	nanoparticle	NOUN
brainmatters-688	132	7	transport	transport	VERB
brainmatters-688	132	8	peptides	peptide	NOUN
brainmatters-688	132	9	across	across	ADP
brainmatters-688	132	10	the	the	DET
brainmatters-688	132	11	blood	blood	NOUN
brainmatters-688	132	12	—	—	PUNCT
brainmatters-688	132	13	brain	brain	NOUN
brainmatters-688	132	14	barrier	barrier	NOUN
brainmatters-688	132	15	and	and	CCONJ
brainmatters-688	132	16	provide	provide	VERB
brainmatters-688	132	17	neuroprotection	neuroprotection	NOUN
brainmatters-688	132	18	.	.	PUNCT
brainmatters-688	133	1	journal	journal	NOUN
brainmatters-688	133	2	of	of	ADP
brainmatters-688	133	3	cerebral	cerebral	ADJ
brainmatters-688	133	4	blood	blood	NOUN
brainmatters-688	133	5	flow	flow	NOUN
brainmatters-688	133	6	&	&	CCONJ
brainmatters-688	133	7	metabolism	metabolism	NOUN
brainmatters-688	133	8	,	,	PUNCT
brainmatters-688	133	9	35(3	35(3	NUM
brainmatters-688	133	10	)	)	PUNCT
brainmatters-688	133	11	,	,	PUNCT
brainmatters-688	133	12	469	469	NUM
brainmatters-688	133	13	-	-	SYM
brainmatters-688	133	14	475	475	NUM
brainmatters-688	133	15	.	.	PUNCT
brainmatters-688	134	1	brain	brain	NOUN
brainmatters-688	134	2	matters	matter	NOUN
brainmatters-688	134	3	volume	volume	VERB
brainmatters-688	134	4	2	2	NUM
brainmatters-688	134	5	8	8	NUM