id	sid	tid	token	lemma	pos
brainmatters-862	1	1	introduction	introduction	NOUN
brainmatters-862	1	2	one	one	NUM
brainmatters-862	1	3	of	of	ADP
brainmatters-862	1	4	the	the	DET
brainmatters-862	1	5	negative	negative	ADJ
brainmatters-862	1	6	consequences	consequence	NOUN
brainmatters-862	1	7	of	of	ADP
brainmatters-862	1	8	cancer	cancer	NOUN
brainmatters-862	1	9	is	be	AUX
brainmatters-862	1	10	the	the	DET
brainmatters-862	1	11	continuous	continuous	ADJ
brainmatters-862	1	12	and	and	CCONJ
brainmatters-862	1	13	unregulated	unregulated	ADJ
brainmatters-862	1	14	proliferation	proliferation	NOUN
brainmatters-862	1	15	of	of	ADP
brainmatters-862	1	16	cancer	cancer	NOUN
brainmatters-862	1	17	cells	cell	NOUN
brainmatters-862	1	18	.	.	PUNCT
brainmatters-862	2	1	unlike	unlike	ADP
brainmatters-862	2	2	regular	regular	ADJ
brainmatters-862	2	3	cells	cell	NOUN
brainmatters-862	2	4	which	which	PRON
brainmatters-862	2	5	grow	grow	VERB
brainmatters-862	2	6	to	to	PART
brainmatters-862	2	7	appropriately	appropriately	ADV
brainmatters-862	2	8	regulated	regulate	VERB
brainmatters-862	2	9	signals	signal	NOUN
brainmatters-862	2	10	,	,	PUNCT
brainmatters-862	2	11	cancer	cancer	NOUN
brainmatters-862	2	12	cells	cell	NOUN
brainmatters-862	2	13	grow	grow	VERB
brainmatters-862	2	14	and	and	CCONJ
brainmatters-862	2	15	divide	divide	VERB
brainmatters-862	2	16	“	"	PUNCT
brainmatters-862	2	17	uncontrollably	uncontrollably	ADV
brainmatters-862	2	18	”	"	PUNCT
brainmatters-862	2	19	,	,	PUNCT
brainmatters-862	2	20	spreading	spread	VERB
brainmatters-862	2	21	to	to	ADP
brainmatters-862	2	22	normal	normal	ADJ
brainmatters-862	2	23	tissues	tissue	NOUN
brainmatters-862	2	24	and	and	CCONJ
brainmatters-862	2	25	organs	organ	NOUN
brainmatters-862	2	26	throughout	throughout	ADP
brainmatters-862	2	27	the	the	DET
brainmatters-862	2	28	body	body	NOUN
brainmatters-862	2	29	by	by	ADP
brainmatters-862	2	30	a	a	DET
brainmatters-862	2	31	process	process	NOUN
brainmatters-862	2	32	called	call	VERB
brainmatters-862	2	33	metastasis	metastasis	NOUN
brainmatters-862	2	34	.	.	PUNCT
brainmatters-862	3	1	(	(	PUNCT
brainmatters-862	3	2	cooper	cooper	NOUN
brainmatters-862	3	3	,	,	PUNCT
brainmatters-862	3	4	2000	2000	NUM
brainmatters-862	3	5	)	)	PUNCT
brainmatters-862	3	6	the	the	DET
brainmatters-862	3	7	unregulated	unregulated	ADJ
brainmatters-862	3	8	growth	growth	NOUN
brainmatters-862	3	9	of	of	ADP
brainmatters-862	3	10	cancer	cancer	NOUN
brainmatters-862	3	11	cells	cell	NOUN
brainmatters-862	3	12	is	be	AUX
brainmatters-862	3	13	the	the	DET
brainmatters-862	3	14	result	result	NOUN
brainmatters-862	3	15	of	of	ADP
brainmatters-862	3	16	an	an	DET
brainmatters-862	3	17	accumulation	accumulation	NOUN
brainmatters-862	3	18	of	of	ADP
brainmatters-862	3	19	abnormalities	abnormality	NOUN
brainmatters-862	3	20	within	within	ADP
brainmatters-862	3	21	multiple	multiple	ADJ
brainmatters-862	3	22	cell	cell	NOUN
brainmatters-862	3	23	regulatory	regulatory	ADJ
brainmatters-862	3	24	systems	system	NOUN
brainmatters-862	3	25	and	and	CCONJ
brainmatters-862	3	26	is	be	AUX
brainmatters-862	3	27	reflected	reflect	VERB
brainmatters-862	3	28	in	in	ADP
brainmatters-862	3	29	a	a	DET
brainmatters-862	3	30	manner	manner	NOUN
brainmatters-862	3	31	that	that	PRON
brainmatters-862	3	32	distinguishes	distinguish	VERB
brainmatters-862	3	33	cancer	cancer	NOUN
brainmatters-862	3	34	cells	cell	NOUN
brainmatters-862	3	35	from	from	ADP
brainmatters-862	3	36	their	their	PRON
brainmatters-862	3	37	counterparts	counterpart	NOUN
brainmatters-862	3	38	.	.	PUNCT
brainmatters-862	4	1	these	these	DET
brainmatters-862	4	2	abnormalities	abnormality	NOUN
brainmatters-862	4	3	can	can	AUX
brainmatters-862	4	4	range	range	VERB
brainmatters-862	4	5	from	from	ADP
brainmatters-862	4	6	various	various	ADJ
brainmatters-862	4	7	types	type	NOUN
brainmatters-862	4	8	of	of	ADP
brainmatters-862	4	9	mutations	mutation	NOUN
brainmatters-862	4	10	in	in	ADP
brainmatters-862	4	11	the	the	DET
brainmatters-862	4	12	dna	dna	PROPN
brainmatters-862	4	13	sequence	sequence	NOUN
brainmatters-862	4	14	that	that	PRON
brainmatters-862	4	15	can	can	AUX
brainmatters-862	4	16	either	either	CCONJ
brainmatters-862	4	17	cause	cause	VERB
brainmatters-862	4	18	issues	issue	NOUN
brainmatters-862	4	19	with	with	ADP
brainmatters-862	4	20	tumor	tumor	NOUN
brainmatters-862	4	21	suppressor	suppressor	NOUN
brainmatters-862	4	22	genes	gene	NOUN
brainmatters-862	4	23	or	or	CCONJ
brainmatters-862	4	24	activating	activate	VERB
brainmatters-862	4	25	cancer	cancer	NOUN
brainmatters-862	4	26	promoting	promote	VERB
brainmatters-862	4	27	genes	gene	NOUN
brainmatters-862	4	28	.	.	PUNCT
brainmatters-862	5	1	with	with	ADP
brainmatters-862	5	2	respect	respect	NOUN
brainmatters-862	5	3	to	to	ADP
brainmatters-862	5	4	cancer	cancer	NOUN
brainmatters-862	5	5	pathology	pathology	NOUN
brainmatters-862	5	6	,	,	PUNCT
brainmatters-862	5	7	the	the	DET
brainmatters-862	5	8	most	most	ADV
brainmatters-862	5	9	important	important	ADJ
brainmatters-862	5	10	issue	issue	NOUN
brainmatters-862	5	11	is	be	AUX
brainmatters-862	5	12	the	the	DET
brainmatters-862	5	13	distinction	distinction	NOUN
brainmatters-862	5	14	between	between	ADP
brainmatters-862	5	15	malignant	malignant	ADJ
brainmatters-862	5	16	and	and	CCONJ
brainmatters-862	5	17	benign	benign	ADJ
brainmatters-862	5	18	tumors	tumor	NOUN
brainmatters-862	5	19	.	.	PUNCT
brainmatters-862	6	1	(	(	PUNCT
brainmatters-862	6	2	cooper	cooper	NOUN
brainmatters-862	6	3	,	,	PUNCT
brainmatters-862	6	4	2000	2000	NUM
brainmatters-862	6	5	)	)	PUNCT
brainmatters-862	6	6	a	a	DET
brainmatters-862	6	7	tumor	tumor	NOUN
brainmatters-862	6	8	is	be	AUX
brainmatters-862	6	9	any	any	DET
brainmatters-862	6	10	abnormal	abnormal	ADJ
brainmatters-862	6	11	proliferation	proliferation	NOUN
brainmatters-862	6	12	of	of	ADP
brainmatters-862	6	13	cells	cell	NOUN
brainmatters-862	6	14	.	.	PUNCT
brainmatters-862	7	1	a	a	DET
brainmatters-862	7	2	benign	benign	ADJ
brainmatters-862	7	3	tumor	tumor	NOUN
brainmatters-862	7	4	such	such	ADJ
brainmatters-862	7	5	as	as	ADP
brainmatters-862	7	6	a	a	DET
brainmatters-862	7	7	skin	skin	NOUN
brainmatters-862	7	8	wart	wart	NOUN
brainmatters-862	7	9	remains	remain	VERB
brainmatters-862	7	10	stagnant	stagnant	ADJ
brainmatters-862	7	11	in	in	ADP
brainmatters-862	7	12	a	a	DET
brainmatters-862	7	13	specific	specific	ADJ
brainmatters-862	7	14	location	location	NOUN
brainmatters-862	7	15	and	and	CCONJ
brainmatters-862	7	16	does	do	AUX
brainmatters-862	7	17	not	not	PART
brainmatters-862	7	18	spread	spread	VERB
brainmatters-862	7	19	to	to	ADP
brainmatters-862	7	20	other	other	ADJ
brainmatters-862	7	21	tissues	tissue	NOUN
brainmatters-862	7	22	and	and	CCONJ
brainmatters-862	7	23	parts	part	NOUN
brainmatters-862	7	24	of	of	ADP
brainmatters-862	7	25	the	the	DET
brainmatters-862	7	26	body	body	NOUN
brainmatters-862	7	27	.	.	PUNCT
brainmatters-862	8	1	a	a	DET
brainmatters-862	8	2	malignant	malignant	ADJ
brainmatters-862	8	3	tumor	tumor	NOUN
brainmatters-862	8	4	can	can	AUX
brainmatters-862	8	5	spread	spread	VERB
brainmatters-862	8	6	to	to	ADP
brainmatters-862	8	7	nearby	nearby	ADJ
brainmatters-862	8	8	tissues	tissue	NOUN
brainmatters-862	8	9	as	as	ADV
brainmatters-862	8	10	well	well	ADV
brainmatters-862	8	11	as	as	ADP
brainmatters-862	8	12	throughout	throughout	ADP
brainmatters-862	8	13	the	the	DET
brainmatters-862	8	14	body	body	NOUN
brainmatters-862	8	15	via	via	ADP
brainmatters-862	8	16	the	the	DET
brainmatters-862	8	17	circulatory	circulatory	ADJ
brainmatters-862	8	18	and	and	CCONJ
brainmatters-862	8	19	lymphatic	lymphatic	ADJ
brainmatters-862	8	20	systems	system	NOUN
brainmatters-862	8	21	through	through	ADP
brainmatters-862	8	22	metastasis	metastasis	NOUN
brainmatters-862	8	23	.	.	PUNCT
brainmatters-862	9	1	(	(	PUNCT
brainmatters-862	9	2	cooper	cooper	NOUN
brainmatters-862	9	3	,	,	PUNCT
brainmatters-862	9	4	2000	2000	NUM
brainmatters-862	9	5	)	)	PUNCT
brainmatters-862	9	6	.	.	PUNCT
brainmatters-862	10	1	brain	brain	NOUN
brainmatters-862	10	2	tumors	tumor	NOUN
brainmatters-862	10	3	are	be	AUX
brainmatters-862	10	4	a	a	DET
brainmatters-862	10	5	collection	collection	NOUN
brainmatters-862	10	6	of	of	ADP
brainmatters-862	10	7	neoplasms	neoplasm	NOUN
brainmatters-862	10	8	that	that	PRON
brainmatters-862	10	9	arise	arise	VERB
brainmatters-862	10	10	either	either	CCONJ
brainmatters-862	10	11	from	from	ADP
brainmatters-862	10	12	within	within	ADP
brainmatters-862	10	13	the	the	DET
brainmatters-862	10	14	brain	brain	NOUN
brainmatters-862	10	15	itself	itself	PRON
brainmatters-862	10	16	,	,	PUNCT
brainmatters-862	10	17	or	or	CCONJ
brainmatters-862	10	18	from	from	ADP
brainmatters-862	10	19	systemic	systemic	ADJ
brainmatters-862	10	20	tumors	tumor	NOUN
brainmatters-862	10	21	that	that	PRON
brainmatters-862	10	22	have	have	AUX
brainmatters-862	10	23	metastasized	metastasize	VERB
brainmatters-862	10	24	to	to	ADP
brainmatters-862	10	25	the	the	DET
brainmatters-862	10	26	brain	brain	NOUN
brainmatters-862	10	27	.	.	PUNCT
brainmatters-862	11	1	symptoms	symptom	NOUN
brainmatters-862	11	2	of	of	ADP
brainmatters-862	11	3	brain	brain	NOUN
brainmatters-862	11	4	tumors	tumor	NOUN
brainmatters-862	11	5	include	include	VERB
brainmatters-862	11	6	seizures	seizure	NOUN
brainmatters-862	11	7	,	,	PUNCT
brainmatters-862	11	8	headaches	headache	NOUN
brainmatters-862	11	9	,	,	PUNCT
brainmatters-862	11	10	fatigue	fatigue	NOUN
brainmatters-862	11	11	and	and	CCONJ
brainmatters-862	11	12	cognitive	cognitive	ADJ
brainmatters-862	11	13	dysfunction	dysfunction	NOUN
brainmatters-862	11	14	.	.	PUNCT
brainmatters-862	12	1	(	(	PUNCT
brainmatters-862	12	2	butowski	butowski	NOUN
brainmatters-862	12	3	,	,	PUNCT
brainmatters-862	12	4	2015	2015	NUM
brainmatters-862	12	5	)	)	PUNCT
brainmatters-862	12	6	there	there	PRON
brainmatters-862	12	7	are	be	VERB
brainmatters-862	12	8	currently	currently	ADV
brainmatters-862	12	9	over	over	ADP
brainmatters-862	12	10	120	120	NUM
brainmatters-862	12	11	types	type	NOUN
brainmatters-862	12	12	of	of	ADP
brainmatters-862	12	13	cancers	cancer	NOUN
brainmatters-862	12	14	and	and	CCONJ
brainmatters-862	12	15	tumors	tumor	NOUN
brainmatters-862	12	16	that	that	PRON
brainmatters-862	12	17	effect	effect	VERB
brainmatters-862	12	18	the	the	DET
brainmatters-862	12	19	brain	brain	NOUN
brainmatters-862	12	20	,	,	PUNCT
brainmatters-862	12	21	however	however	ADV
brainmatters-862	12	22	some	some	PRON
brainmatters-862	12	23	of	of	ADP
brainmatters-862	12	24	the	the	DET
brainmatters-862	12	25	more	more	ADV
brainmatters-862	12	26	common	common	ADJ
brainmatters-862	12	27	ones	one	NOUN
brainmatters-862	12	28	are	be	AUX
brainmatters-862	12	29	pilocytic	pilocytic	ADJ
brainmatters-862	12	30	astrocytoma	astrocytoma	PROPN
brainmatters-862	12	31	’s	’s	NOUN
brainmatters-862	12	32	,	,	PUNCT
brainmatters-862	12	33	ependymomas	ependymoma	VERB
brainmatters-862	12	34	,	,	PUNCT
brainmatters-862	12	35	and	and	CCONJ
brainmatters-862	12	36	medulloblastomas	medulloblastoma	NOUN
brainmatters-862	12	37	in	in	ADP
brainmatters-862	12	38	children	child	NOUN
brainmatters-862	12	39	,	,	PUNCT
brainmatters-862	12	40	and	and	CCONJ
brainmatters-862	12	41	the	the	DET
brainmatters-862	12	42	diffuse	diffuse	PROPN
brainmatters-862	12	43	astrocytic	astrocytic	ADJ
brainmatters-862	12	44	tumours	tumour	NOUN
brainmatters-862	12	45	(	(	PUNCT
brainmatters-862	12	46	including	include	VERB
brainmatters-862	12	47	astrocytoma	astrocytoma	NOUN
brainmatters-862	12	48	,	,	PUNCT
brainmatters-862	12	49	anaplastic	anaplastic	ADJ
brainmatters-862	12	50	astrocytoma	astrocytoma	NOUN
brainmatters-862	12	51	’s	’s	PART
brainmatters-862	12	52	,	,	PUNCT
brainmatters-862	12	53	and	and	CCONJ
brainmatters-862	12	54	glioblastomas	glioblastoma	NOUN
brainmatters-862	12	55	)	)	PUNCT
brainmatters-862	12	56	,	,	PUNCT
brainmatters-862	12	57	oligodendroglia	oligodendroglia	VERB
brainmatters-862	12	58	’s	’s	PART
brainmatters-862	12	59	,	,	PUNCT
brainmatters-862	12	60	and	and	CCONJ
brainmatters-862	12	61	meningioma	meningioma	NOUN
brainmatters-862	12	62	’s	’s	X
brainmatters-862	12	63	in	in	ADP
brainmatters-862	12	64	adults	adult	NOUN
brainmatters-862	12	65	.	.	PUNCT
brainmatters-862	13	1	(	(	PUNCT
brainmatters-862	13	2	collins	collins	PROPN
brainmatters-862	13	3	,	,	PUNCT
brainmatters-862	13	4	2004	2004	NUM
brainmatters-862	13	5	)	)	PUNCT
brainmatters-862	13	6	.	.	PUNCT
brainmatters-862	14	1	ependymomas	ependymomas	PROPN
brainmatters-862	14	2	are	be	AUX
brainmatters-862	14	3	glial	glial	ADJ
brainmatters-862	14	4	cell	cell	NOUN
brainmatters-862	14	5	tumors	tumor	NOUN
brainmatters-862	14	6	that	that	PRON
brainmatters-862	14	7	typically	typically	ADV
brainmatters-862	14	8	arise	arise	VERB
brainmatters-862	14	9	from	from	ADP
brainmatters-862	14	10	the	the	DET
brainmatters-862	14	11	lining	lining	NOUN
brainmatters-862	14	12	cells	cell	NOUN
brainmatters-862	14	13	of	of	ADP
brainmatters-862	14	14	the	the	DET
brainmatters-862	14	15	blood	blood	NOUN
brainmatters-862	14	16	vessels	vessel	NOUN
brainmatters-862	14	17	of	of	ADP
brainmatters-862	14	18	the	the	DET
brainmatters-862	14	19	brain	brain	NOUN
brainmatters-862	14	20	and	and	CCONJ
brainmatters-862	14	21	are	be	AUX
brainmatters-862	14	22	less	less	ADV
brainmatters-862	14	23	known	known	ADJ
brainmatters-862	14	24	to	to	PART
brainmatters-862	14	25	be	be	AUX
brainmatters-862	14	26	found	find	VERB
brainmatters-862	14	27	outside	outside	ADV
brainmatters-862	14	28	of	of	ADP
brainmatters-862	14	29	the	the	DET
brainmatters-862	14	30	central	central	ADJ
brainmatters-862	14	31	nervous	nervous	ADJ
brainmatters-862	14	32	system	system	NOUN
brainmatters-862	14	33	.	.	PUNCT
brainmatters-862	15	1	these	these	DET
brainmatters-862	15	2	tumors	tumor	NOUN
brainmatters-862	15	3	are	be	AUX
brainmatters-862	15	4	genetically	genetically	ADV
brainmatters-862	15	5	distinct	distinct	ADJ
brainmatters-862	15	6	from	from	ADP
brainmatters-862	15	7	each	each	DET
brainmatters-862	15	8	other	other	ADJ
brainmatters-862	15	9	and	and	CCONJ
brainmatters-862	15	10	affect	affect	VERB
brainmatters-862	15	11	children	child	NOUN
brainmatters-862	15	12	more	more	ADJ
brainmatters-862	15	13	than	than	ADP
brainmatters-862	15	14	adults	adult	NOUN
brainmatters-862	15	15	.	.	PUNCT
brainmatters-862	16	1	(	(	PUNCT
brainmatters-862	16	2	zamora	zamora	PROPN
brainmatters-862	16	3	,	,	PUNCT
brainmatters-862	16	4	2020	2020	NUM
brainmatters-862	16	5	)	)	PUNCT
brainmatters-862	16	6	ependymoma	ependymoma	VERB
brainmatters-862	16	7	tumor	tumor	NOUN
brainmatters-862	16	8	diagnosis	diagnosis	NOUN
brainmatters-862	16	9	:	:	PUNCT
brainmatters-862	16	10	pathophysiology	pathophysiology	NOUN
brainmatters-862	16	11	and	and	CCONJ
brainmatters-862	16	12	prognosis	prognosis	NOUN
brainmatters-862	16	13	of	of	ADP
brainmatters-862	16	14	pediatric	pediatric	ADJ
brainmatters-862	16	15	and	and	CCONJ
brainmatters-862	16	16	adult	adult	NOUN
brainmatters-862	16	17	patients	patient	NOUN
brainmatters-862	16	18	christopher	christopher	PROPN
brainmatters-862	16	19	jones	jones	PROPN
brainmatters-862	16	20	ependymomas	ependymomas	PROPN
brainmatters-862	16	21	are	be	AUX
brainmatters-862	16	22	a	a	DET
brainmatters-862	16	23	rare	rare	ADJ
brainmatters-862	16	24	type	type	NOUN
brainmatters-862	16	25	of	of	ADP
brainmatters-862	16	26	tumor	tumor	NOUN
brainmatters-862	16	27	that	that	PRON
brainmatters-862	16	28	affects	affect	VERB
brainmatters-862	16	29	the	the	DET
brainmatters-862	16	30	central	central	ADJ
brainmatters-862	16	31	nervous	nervous	ADJ
brainmatters-862	16	32	system	system	NOUN
brainmatters-862	16	33	(	(	PUNCT
brainmatters-862	16	34	cns	cns	NOUN
brainmatters-862	16	35	)	)	PUNCT
brainmatters-862	16	36	of	of	ADP
brainmatters-862	16	37	adolescents	adolescent	NOUN
brainmatters-862	16	38	and	and	CCONJ
brainmatters-862	16	39	adults	adult	NOUN
brainmatters-862	16	40	.	.	PUNCT
brainmatters-862	17	1	the	the	DET
brainmatters-862	17	2	tumor	tumor	NOUN
brainmatters-862	17	3	derives	derive	VERB
brainmatters-862	17	4	from	from	ADP
brainmatters-862	17	5	the	the	DET
brainmatters-862	17	6	ependymal	ependymal	ADJ
brainmatters-862	17	7	cells	cell	NOUN
brainmatters-862	17	8	which	which	PRON
brainmatters-862	17	9	are	be	AUX
brainmatters-862	17	10	responsible	responsible	ADJ
brainmatters-862	17	11	for	for	ADP
brainmatters-862	17	12	lining	line	VERB
brainmatters-862	17	13	the	the	DET
brainmatters-862	17	14	ventricles	ventricle	NOUN
brainmatters-862	17	15	containing	contain	VERB
brainmatters-862	17	16	cerebrospinal	cerebrospinal	ADJ
brainmatters-862	17	17	fluid	fluid	NOUN
brainmatters-862	17	18	within	within	ADP
brainmatters-862	17	19	the	the	DET
brainmatters-862	17	20	brain	brain	NOUN
brainmatters-862	17	21	and	and	CCONJ
brainmatters-862	17	22	spinal	spinal	ADJ
brainmatters-862	17	23	cord	cord	NOUN
brainmatters-862	17	24	.	.	PUNCT
brainmatters-862	18	1	while	while	SCONJ
brainmatters-862	18	2	pediatric	pediatric	ADJ
brainmatters-862	18	3	patients	patient	NOUN
brainmatters-862	18	4	are	be	AUX
brainmatters-862	18	5	more	more	ADV
brainmatters-862	18	6	likely	likely	ADJ
brainmatters-862	18	7	to	to	PART
brainmatters-862	18	8	develop	develop	VERB
brainmatters-862	18	9	the	the	DET
brainmatters-862	18	10	tumor	tumor	NOUN
brainmatters-862	18	11	in	in	ADP
brainmatters-862	18	12	the	the	DET
brainmatters-862	18	13	brain	brain	NOUN
brainmatters-862	18	14	,	,	PUNCT
brainmatters-862	18	15	adult	adult	NOUN
brainmatters-862	18	16	patients	patient	NOUN
brainmatters-862	18	17	mainly	mainly	ADV
brainmatters-862	18	18	develop	develop	VERB
brainmatters-862	18	19	the	the	DET
brainmatters-862	18	20	tumor	tumor	NOUN
brainmatters-862	18	21	in	in	ADP
brainmatters-862	18	22	the	the	DET
brainmatters-862	18	23	spinal	spinal	ADJ
brainmatters-862	18	24	cord	cord	NOUN
brainmatters-862	18	25	region	region	NOUN
brainmatters-862	18	26	.	.	PUNCT
brainmatters-862	19	1	(	(	PUNCT
brainmatters-862	19	2	gerstner	gerstner	NOUN
brainmatters-862	19	3	,	,	PUNCT
brainmatters-862	19	4	2018	2018	NUM
brainmatters-862	19	5	)	)	PUNCT
brainmatters-862	19	6	.	.	PUNCT
brainmatters-862	20	1	ependymomas	ependymomas	PROPN
brainmatters-862	20	2	range	range	VERB
brainmatters-862	20	3	from	from	ADP
brainmatters-862	20	4	being	be	AUX
brainmatters-862	20	5	slow	slow	ADJ
brainmatters-862	20	6	growing	grow	VERB
brainmatters-862	20	7	grade	grade	NOUN
brainmatters-862	20	8	i	i	PRON
brainmatters-862	20	9	tumors	tumor	NOUN
brainmatters-862	20	10	to	to	PART
brainmatters-862	20	11	malignant	malignant	VERB
brainmatters-862	20	12	and	and	CCONJ
brainmatters-862	20	13	fast	fast	ADV
brainmatters-862	20	14	growing	grow	VERB
brainmatters-862	20	15	grade	grade	NOUN
brainmatters-862	20	16	iii	iii	NUM
brainmatters-862	20	17	tumors	tumor	NOUN
brainmatters-862	20	18	which	which	PRON
brainmatters-862	20	19	are	be	AUX
brainmatters-862	20	20	known	know	VERB
brainmatters-862	20	21	as	as	ADP
brainmatters-862	20	22	anaplastic	anaplastic	ADJ
brainmatters-862	20	23	.	.	PUNCT
brainmatters-862	21	1	current	current	ADJ
brainmatters-862	21	2	medical	medical	ADJ
brainmatters-862	21	3	treatments	treatment	NOUN
brainmatters-862	21	4	for	for	ADP
brainmatters-862	21	5	this	this	DET
brainmatters-862	21	6	tumor	tumor	NOUN
brainmatters-862	21	7	provide	provide	VERB
brainmatters-862	21	8	more	more	ADV
brainmatters-862	21	9	positive	positive	ADJ
brainmatters-862	21	10	outcomes	outcome	NOUN
brainmatters-862	21	11	for	for	ADP
brainmatters-862	21	12	adult	adult	NOUN
brainmatters-862	21	13	patients	patient	NOUN
brainmatters-862	21	14	versus	versus	ADP
brainmatters-862	21	15	pediatric	pediatric	ADJ
brainmatters-862	21	16	patients	patient	NOUN
brainmatters-862	21	17	.	.	PUNCT
brainmatters-862	22	1	this	this	DET
brainmatters-862	22	2	paper	paper	NOUN
brainmatters-862	22	3	will	will	AUX
brainmatters-862	22	4	explore	explore	VERB
brainmatters-862	22	5	the	the	DET
brainmatters-862	22	6	pathophysiology	pathophysiology	NOUN
brainmatters-862	22	7	of	of	ADP
brainmatters-862	22	8	the	the	DET
brainmatters-862	22	9	disease	disease	NOUN
brainmatters-862	22	10	in	in	ADP
brainmatters-862	22	11	both	both	DET
brainmatters-862	22	12	patient	patient	ADJ
brainmatters-862	22	13	types	type	NOUN
brainmatters-862	22	14	in	in	ADP
brainmatters-862	22	15	order	order	NOUN
brainmatters-862	22	16	to	to	PART
brainmatters-862	22	17	provide	provide	VERB
brainmatters-862	22	18	insight	insight	NOUN
brainmatters-862	22	19	into	into	ADP
brainmatters-862	22	20	possible	possible	ADJ
brainmatters-862	22	21	differences	difference	NOUN
brainmatters-862	22	22	that	that	PRON
brainmatters-862	22	23	better	well	ADV
brainmatters-862	22	24	explain	explain	VERB
brainmatters-862	22	25	the	the	DET
brainmatters-862	22	26	clinical	clinical	ADJ
brainmatters-862	22	27	outcome	outcome	NOUN
brainmatters-862	22	28	abstract	abstract	ADJ
brainmatters-862	22	29	ependymomas	ependymomas	PROPN
brainmatters-862	22	30	explained	explain	VERB
brainmatters-862	22	31	since	since	SCONJ
brainmatters-862	22	32	ependymomas	ependymoma	NOUN
brainmatters-862	22	33	rarely	rarely	ADV
brainmatters-862	22	34	spread	spread	VERB
brainmatters-862	22	35	outside	outside	ADP
brainmatters-862	22	36	the	the	DET
brainmatters-862	22	37	central	central	ADJ
brainmatters-862	22	38	nervous	nervous	ADJ
brainmatters-862	22	39	system	system	NOUN
brainmatters-862	22	40	,	,	PUNCT
brainmatters-862	22	41	they	they	PRON
brainmatters-862	22	42	do	do	AUX
brainmatters-862	22	43	not	not	PART
brainmatters-862	22	44	follow	follow	VERB
brainmatters-862	22	45	the	the	DET
brainmatters-862	22	46	typical	typical	ADJ
brainmatters-862	22	47	classification	classification	NOUN
brainmatters-862	22	48	system	system	NOUN
brainmatters-862	22	49	.	.	PUNCT
brainmatters-862	23	1	the	the	DET
brainmatters-862	23	2	classification	classification	NOUN
brainmatters-862	23	3	starts	start	VERB
brainmatters-862	23	4	with	with	ADP
brainmatters-862	23	5	grade	grade	NOUN
brainmatters-862	23	6	i	i	PRON
brainmatters-862	23	7	tumors	tumor	NOUN
brainmatters-862	23	8	which	which	PRON
brainmatters-862	23	9	are	be	AUX
brainmatters-862	23	10	slow	slow	ADJ
brainmatters-862	23	11	growing	grow	VERB
brainmatters-862	23	12	and	and	CCONJ
brainmatters-862	23	13	are	be	AUX
brainmatters-862	23	14	often	often	ADV
brainmatters-862	23	15	considered	consider	VERB
brainmatters-862	23	16	benign	benign	ADJ
brainmatters-862	23	17	,	,	PUNCT
brainmatters-862	23	18	including	include	VERB
brainmatters-862	23	19	subependymomas	subependymoma	NOUN
brainmatters-862	23	20	and	and	CCONJ
brainmatters-862	23	21	myxopapillary	myxopapillary	ADJ
brainmatters-862	23	22	ependymomas	ependymoma	NOUN
brainmatters-862	23	23	.	.	PUNCT
brainmatters-862	24	1	this	this	PRON
brainmatters-862	24	2	means	mean	VERB
brainmatters-862	24	3	they	they	PRON
brainmatters-862	24	4	are	be	AUX
brainmatters-862	24	5	less	less	ADV
brainmatters-862	24	6	likely	likely	ADJ
brainmatters-862	24	7	to	to	PART
brainmatters-862	24	8	be	be	AUX
brainmatters-862	24	9	fatal	fatal	ADJ
brainmatters-862	24	10	.	.	PUNCT
brainmatters-862	25	1	subependymomas	subependymomas	PROPN
brainmatters-862	25	2	arise	arise	VERB
brainmatters-862	25	3	in	in	ADP
brainmatters-862	25	4	the	the	DET
brainmatters-862	25	5	ventricular	ventricular	ADJ
brainmatters-862	25	6	walls	wall	NOUN
brainmatters-862	25	7	and	and	CCONJ
brainmatters-862	25	8	are	be	AUX
brainmatters-862	25	9	common	common	ADJ
brainmatters-862	25	10	in	in	ADP
brainmatters-862	25	11	the	the	DET
brainmatters-862	25	12	fourth	fourth	ADJ
brainmatters-862	25	13	or	or	CCONJ
brainmatters-862	25	14	lateral	lateral	ADJ
brainmatters-862	25	15	ventricles	ventricle	NOUN
brainmatters-862	25	16	.	.	PUNCT
brainmatters-862	26	1	they	they	PRON
brainmatters-862	26	2	are	be	AUX
brainmatters-862	26	3	histologically	histologically	ADV
brainmatters-862	26	4	characterized	characterize	VERB
brainmatters-862	26	5	by	by	ADP
brainmatters-862	26	6	a	a	DET
brainmatters-862	26	7	hypocellular	hypocellular	ADJ
brainmatters-862	26	8	tissue	tissue	NOUN
brainmatters-862	26	9	presenting	present	VERB
brainmatters-862	26	10	clusters	cluster	NOUN
brainmatters-862	26	11	of	of	ADP
brainmatters-862	26	12	cells	cell	NOUN
brainmatters-862	26	13	with	with	ADP
brainmatters-862	26	14	a	a	DET
brainmatters-862	26	15	bland	bland	ADJ
brainmatters-862	26	16	nucleus	nucleus	NOUN
brainmatters-862	26	17	surrounded	surround	VERB
brainmatters-862	26	18	by	by	ADP
brainmatters-862	26	19	glial	glial	ADJ
brainmatters-862	26	20	matrix	matrix	NOUN
brainmatters-862	26	21	.	.	PUNCT
brainmatters-862	27	1	myxopapillary	myxopapillary	ADJ
brainmatters-862	27	2	ependymomas	ependymomas	PROPN
brainmatters-862	27	3	arise	arise	VERB
brainmatters-862	27	4	in	in	ADP
brainmatters-862	27	5	the	the	DET
brainmatters-862	27	6	cauda	cauda	NOUN
brainmatters-862	27	7	equina	equina	PROPN
brainmatters-862	27	8	,	,	PUNCT
brainmatters-862	27	9	filum	filum	ADJ
brainmatters-862	27	10	terminale	terminale	NOUN
brainmatters-862	27	11	or	or	CCONJ
brainmatters-862	27	12	conus	conus	NOUN
brainmatters-862	27	13	medullaris	medullaris	NOUN
brainmatters-862	27	14	,	,	PUNCT
brainmatters-862	27	15	and	and	CCONJ
brainmatters-862	27	16	present	present	ADJ
brainmatters-862	27	17	histologically	histologically	ADV
brainmatters-862	27	18	as	as	ADP
brainmatters-862	27	19	pseudopapillary	pseudopapillary	ADJ
brainmatters-862	27	20	structures	structure	NOUN
brainmatters-862	27	21	with	with	ADP
brainmatters-862	27	22	mucin	mucin	NOUN
brainmatters-862	27	23	-	-	PUNCT
brainmatters-862	27	24	rich	rich	ADJ
brainmatters-862	27	25	microcysts	microcyst	NOUN
brainmatters-862	27	26	,	,	PUNCT
brainmatters-862	27	27	the	the	DET
brainmatters-862	27	28	cells	cell	NOUN
brainmatters-862	27	29	are	be	AUX
brainmatters-862	27	30	cuboidal	cuboidal	ADJ
brainmatters-862	27	31	and	and	CCONJ
brainmatters-862	27	32	radially	radially	ADV
brainmatters-862	27	33	arranged	arrange	VERB
brainmatters-862	27	34	surrounding	surround	VERB
brainmatters-862	27	35	a	a	DET
brainmatters-862	27	36	myxoid	myxoid	ADJ
brainmatters-862	27	37	stroma	stroma	NOUN
brainmatters-862	27	38	.	.	PUNCT
brainmatters-862	28	1	these	these	DET
brainmatters-862	28	2	regions	region	NOUN
brainmatters-862	28	3	are	be	AUX
brainmatters-862	28	4	in	in	ADP
brainmatters-862	28	5	the	the	DET
brainmatters-862	28	6	tailbone	tailbone	NOUN
brainmatters-862	28	7	or	or	CCONJ
brainmatters-862	28	8	the	the	DET
brainmatters-862	28	9	base	base	NOUN
brainmatters-862	28	10	of	of	ADP
brainmatters-862	28	11	the	the	DET
brainmatters-862	28	12	spinal	spinal	ADJ
brainmatters-862	28	13	cord	cord	NOUN
brainmatters-862	28	14	.	.	PUNCT
brainmatters-862	29	1	these	these	DET
brainmatters-862	29	2	tumors	tumor	NOUN
brainmatters-862	29	3	would	would	AUX
brainmatters-862	29	4	occur	occur	VERB
brainmatters-862	29	5	in	in	ADP
brainmatters-862	29	6	mostly	mostly	ADV
brainmatters-862	29	7	the	the	DET
brainmatters-862	29	8	adult	adult	NOUN
brainmatters-862	29	9	patient	patient	NOUN
brainmatters-862	29	10	subtype	subtype	NOUN
brainmatters-862	29	11	.	.	PUNCT
brainmatters-862	30	1	grade	grade	PROPN
brainmatters-862	30	2	ii	ii	PROPN
brainmatters-862	30	3	ependymomas	ependymomas	PROPN
brainmatters-862	30	4	are	be	AUX
brainmatters-862	30	5	present	present	ADJ
brainmatters-862	30	6	in	in	ADP
brainmatters-862	30	7	papillary	papillary	ADJ
brainmatters-862	30	8	structures	structure	NOUN
brainmatters-862	30	9	.	.	PUNCT
brainmatters-862	31	1	cells	cell	NOUN
brainmatters-862	31	2	are	be	AUX
brainmatters-862	31	3	arranged	arrange	VERB
brainmatters-862	31	4	regularly	regularly	ADV
brainmatters-862	31	5	and	and	CCONJ
brainmatters-862	31	6	present	present	VERB
brainmatters-862	31	7	a	a	DET
brainmatters-862	31	8	clear	clear	ADJ
brainmatters-862	31	9	cytoplasm	cytoplasm	NOUN
brainmatters-862	31	10	.	.	PUNCT
brainmatters-862	32	1	grade	grade	PROPN
brainmatters-862	32	2	iii	iii	PROPN
brainmatters-862	32	3	,	,	PUNCT
brainmatters-862	32	4	are	be	AUX
brainmatters-862	32	5	anaplastic	anaplastic	ADJ
brainmatters-862	32	6	ependymomas	ependymoma	NOUN
brainmatters-862	32	7	,	,	PUNCT
brainmatters-862	32	8	presenting	present	VERB
brainmatters-862	32	9	with	with	ADP
brainmatters-862	32	10	abundant	abundant	ADJ
brainmatters-862	32	11	mitotic	mitotic	ADJ
brainmatters-862	32	12	cells	cell	NOUN
brainmatters-862	32	13	with	with	ADP
brainmatters-862	32	14	pseudopalisading	pseudopalisade	VERB
brainmatters-862	32	15	necrosis	necrosis	NOUN
brainmatters-862	32	16	.	.	PUNCT
brainmatters-862	33	1	this	this	DET
brainmatters-862	33	2	type	type	NOUN
brainmatters-862	33	3	is	be	AUX
brainmatters-862	33	4	more	more	ADV
brainmatters-862	33	5	deadly	deadly	ADJ
brainmatters-862	33	6	(	(	PUNCT
brainmatters-862	33	7	zamora	zamora	NOUN
brainmatters-862	33	8	,	,	PUNCT
brainmatters-862	33	9	2020	2020	NUM
brainmatters-862	33	10	)	)	PUNCT
brainmatters-862	33	11	.	.	PUNCT
brainmatters-862	34	1	ependymomas	ependymomas	AUX
brainmatters-862	34	2	develop	develop	VERB
brainmatters-862	34	3	in	in	ADP
brainmatters-862	34	4	all	all	DET
brainmatters-862	34	5	age	age	NOUN
brainmatters-862	34	6	groups	group	NOUN
brainmatters-862	34	7	but	but	CCONJ
brainmatters-862	34	8	occur	occur	VERB
brainmatters-862	34	9	mostly	mostly	ADV
brainmatters-862	34	10	in	in	ADP
brainmatters-862	34	11	children	child	NOUN
brainmatters-862	34	12	and	and	CCONJ
brainmatters-862	34	13	rarely	rarely	ADV
brainmatters-862	34	14	in	in	ADP
brainmatters-862	34	15	adults	adult	NOUN
brainmatters-862	34	16	.	.	PUNCT
brainmatters-862	35	1	according	accord	VERB
brainmatters-862	35	2	to	to	ADP
brainmatters-862	35	3	the	the	DET
brainmatters-862	35	4	2014	2014	NUM
brainmatters-862	35	5	report	report	NOUN
brainmatters-862	35	6	published	publish	VERB
brainmatters-862	35	7	by	by	ADP
brainmatters-862	35	8	the	the	DET
brainmatters-862	35	9	central	central	ADJ
brainmatters-862	35	10	brain	brain	NOUN
brainmatters-862	35	11	tumor	tumor	NOUN
brainmatters-862	35	12	registry	registry	NOUN
brainmatters-862	35	13	of	of	ADP
brainmatters-862	35	14	the	the	DET
brainmatters-862	35	15	united	united	PROPN
brainmatters-862	35	16	states	states	PROPN
brainmatters-862	35	17	,	,	PUNCT
brainmatters-862	35	18	ependymomas	ependymomas	PROPN
brainmatters-862	35	19	account	account	PROPN
brainmatters-862	35	20	for	for	ADP
brainmatters-862	35	21	5.2	5.2	NUM
brainmatters-862	35	22	%	%	NOUN
brainmatters-862	35	23	of	of	ADP
brainmatters-862	35	24	all	all	DET
brainmatters-862	35	25	brain	brain	NOUN
brainmatters-862	35	26	and	and	CCONJ
brainmatters-862	35	27	cns	cns	NOUN
brainmatters-862	35	28	imaging	imaging	NOUN
brainmatters-862	35	29	of	of	ADP
brainmatters-862	35	30	a	a	DET
brainmatters-862	35	31	pediatric	pediatric	ADJ
brainmatters-862	35	32	brain	brain	NOUN
brainmatters-862	35	33	tumor	tumor	NOUN
brainmatters-862	35	34	(	(	PUNCT
brainmatters-862	35	35	2020	2020	NUM
brainmatters-862	35	36	)	)	PUNCT
brainmatters-862	35	37	.	.	PUNCT
brainmatters-862	36	1	5	5	NUM
brainmatters-862	36	2	6	6	NUM
brainmatters-862	36	3	tumors	tumor	NOUN
brainmatters-862	36	4	in	in	ADP
brainmatters-862	36	5	children	child	NOUN
brainmatters-862	36	6	and	and	CCONJ
brainmatters-862	36	7	adolescents	adolescent	NOUN
brainmatters-862	36	8	aged	age	VERB
brainmatters-862	36	9	0–19	0–19	NOUN
brainmatters-862	36	10	years	year	NOUN
brainmatters-862	36	11	.	.	PUNCT
brainmatters-862	37	1	with	with	ADP
brainmatters-862	37	2	regards	regard	NOUN
brainmatters-862	37	3	to	to	ADP
brainmatters-862	37	4	ethnicity	ethnicity	NOUN
brainmatters-862	37	5	,	,	PUNCT
brainmatters-862	37	6	the	the	DET
brainmatters-862	37	7	incidence	incidence	NOUN
brainmatters-862	37	8	rate	rate	NOUN
brainmatters-862	37	9	per	per	ADP
brainmatters-862	37	10	100,000	100,000	NUM
brainmatters-862	37	11	is	be	AUX
brainmatters-862	37	12	0.40	0.40	NUM
brainmatters-862	37	13	in	in	ADP
brainmatters-862	37	14	caucasians	caucasian	NOUN
brainmatters-862	37	15	versus	versus	ADP
brainmatters-862	37	16	0.27	0.27	NUM
brainmatters-862	37	17	in	in	ADP
brainmatters-862	37	18	african	african	ADJ
brainmatters-862	37	19	american	american	PROPN
brainmatters-862	37	20	(	(	PUNCT
brainmatters-862	37	21	wu	wu	PROPN
brainmatters-862	37	22	2016	2016	NUM
brainmatters-862	37	23	)	)	PUNCT
brainmatters-862	37	24	.	.	PUNCT
brainmatters-862	38	1	the	the	DET
brainmatters-862	38	2	survival	survival	NOUN
brainmatters-862	38	3	rate	rate	NOUN
brainmatters-862	38	4	is	be	AUX
brainmatters-862	38	5	the	the	DET
brainmatters-862	38	6	highest	high	ADJ
brainmatters-862	38	7	for	for	ADP
brainmatters-862	38	8	those	those	DET
brainmatters-862	38	9	aged	age	VERB
brainmatters-862	38	10	20–44	20–44	NUM
brainmatters-862	38	11	years	year	NOUN
brainmatters-862	38	12	and	and	CCONJ
brainmatters-862	38	13	gets	get	VERB
brainmatters-862	38	14	lower	low	ADJ
brainmatters-862	38	15	with	with	ADP
brainmatters-862	38	16	increasing	increase	VERB
brainmatters-862	38	17	age	age	NOUN
brainmatters-862	38	18	at	at	ADP
brainmatters-862	38	19	the	the	DET
brainmatters-862	38	20	time	time	NOUN
brainmatters-862	38	21	of	of	ADP
brainmatters-862	38	22	the	the	DET
brainmatters-862	38	23	diagnosis	diagnosis	NOUN
brainmatters-862	38	24	.	.	PUNCT
brainmatters-862	39	1	the	the	DET
brainmatters-862	39	2	10	10	NUM
brainmatters-862	39	3	-	-	PUNCT
brainmatters-862	39	4	year	year	NOUN
brainmatters-862	39	5	survival	survival	NOUN
brainmatters-862	39	6	rate	rate	NOUN
brainmatters-862	39	7	is	be	AUX
brainmatters-862	39	8	only	only	ADV
brainmatters-862	39	9	28.1	28.1	NUM
brainmatters-862	39	10	%	%	NOUN
brainmatters-862	39	11	in	in	ADP
brainmatters-862	39	12	those	those	PRON
brainmatters-862	39	13	aged	age	VERB
brainmatters-862	39	14	older	old	ADJ
brainmatters-862	39	15	than	than	ADP
brainmatters-862	39	16	75	75	NUM
brainmatters-862	39	17	years	year	NOUN
brainmatters-862	39	18	.	.	PUNCT
brainmatters-862	40	1	in	in	ADP
brainmatters-862	40	2	children	child	NOUN
brainmatters-862	40	3	and	and	CCONJ
brainmatters-862	40	4	adolescents	adolescent	NOUN
brainmatters-862	40	5	aged	age	VERB
brainmatters-862	40	6	0–19	0–19	NOUN
brainmatters-862	40	7	years	year	NOUN
brainmatters-862	40	8	,	,	PUNCT
brainmatters-862	40	9	the	the	DET
brainmatters-862	40	10	10	10	NUM
brainmatters-862	40	11	-	-	PUNCT
brainmatters-862	40	12	year	year	NOUN
brainmatters-862	40	13	survival	survival	NOUN
brainmatters-862	40	14	rate	rate	NOUN
brainmatters-862	40	15	is	be	AUX
brainmatters-862	40	16	66	66	NUM
brainmatters-862	40	17	%	%	NOUN
brainmatters-862	40	18	.	.	PUNCT
brainmatters-862	41	1	(	(	PUNCT
brainmatters-862	41	2	wu	wu	PROPN
brainmatters-862	41	3	2016	2016	NUM
brainmatters-862	41	4	)	)	PUNCT
brainmatters-862	41	5	the	the	DET
brainmatters-862	41	6	prognosis	prognosis	NOUN
brainmatters-862	41	7	of	of	ADP
brainmatters-862	41	8	this	this	DET
brainmatters-862	41	9	tumor	tumor	NOUN
brainmatters-862	41	10	type	type	NOUN
brainmatters-862	41	11	is	be	AUX
brainmatters-862	41	12	mainly	mainly	ADV
brainmatters-862	41	13	based	base	VERB
brainmatters-862	41	14	on	on	ADP
brainmatters-862	41	15	the	the	DET
brainmatters-862	41	16	location	location	NOUN
brainmatters-862	41	17	of	of	ADP
brainmatters-862	41	18	the	the	DET
brainmatters-862	41	19	tumor	tumor	NOUN
brainmatters-862	41	20	as	as	ADV
brainmatters-862	41	21	well	well	ADV
brainmatters-862	41	22	as	as	ADP
brainmatters-862	41	23	the	the	DET
brainmatters-862	41	24	age	age	NOUN
brainmatters-862	41	25	of	of	ADP
brainmatters-862	41	26	the	the	DET
brainmatters-862	41	27	patient	patient	NOUN
brainmatters-862	41	28	.	.	PUNCT
brainmatters-862	42	1	a	a	DET
brainmatters-862	42	2	study	study	NOUN
brainmatters-862	42	3	conducted	conduct	VERB
brainmatters-862	42	4	by	by	ADP
brainmatters-862	42	5	rodriguez	rodriguez	NOUN
brainmatters-862	42	6	analyzed	analyze	VERB
brainmatters-862	42	7	2408	2408	NUM
brainmatters-862	42	8	ependymoma	ependymoma	NOUN
brainmatters-862	42	9	cases2132	cases2132	PROPN
brainmatters-862	42	10	belonging	belong	VERB
brainmatters-862	42	11	to	to	ADP
brainmatters-862	42	12	the	the	DET
brainmatters-862	42	13	grade	grade	NOUN
brainmatters-862	42	14	2	2	NUM
brainmatters-862	42	15	category	category	NOUN
brainmatters-862	42	16	and	and	CCONJ
brainmatters-862	42	17	276	276	NUM
brainmatters-862	42	18	belonging	belong	VERB
brainmatters-862	42	19	to	to	ADP
brainmatters-862	42	20	the	the	DET
brainmatters-862	42	21	grade	grade	NOUN
brainmatters-862	42	22	3	3	NUM
brainmatters-862	42	23	category	category	NOUN
brainmatters-862	42	24	from	from	ADP
brainmatters-862	42	25	the	the	DET
brainmatters-862	42	26	surveillance	surveillance	NOUN
brainmatters-862	42	27	,	,	PUNCT
brainmatters-862	42	28	epidemiology	epidemiology	NOUN
brainmatters-862	42	29	and	and	CCONJ
brainmatters-862	42	30	end	end	VERB
brainmatters-862	42	31	results	result	NOUN
brainmatters-862	42	32	database	database	VERB
brainmatters-862	42	33	1997–2005	1997–2005	NUM
brainmatters-862	42	34	.	.	PUNCT
brainmatters-862	43	1	some	some	PRON
brainmatters-862	43	2	of	of	ADP
brainmatters-862	43	3	the	the	DET
brainmatters-862	43	4	factors	factor	NOUN
brainmatters-862	43	5	that	that	PRON
brainmatters-862	43	6	contributed	contribute	VERB
brainmatters-862	43	7	to	to	ADP
brainmatters-862	43	8	poor	poor	ADJ
brainmatters-862	43	9	clinical	clinical	ADJ
brainmatters-862	43	10	outcomes	outcome	NOUN
brainmatters-862	43	11	were	be	AUX
brainmatters-862	43	12	younger	young	ADJ
brainmatters-862	43	13	age	age	NOUN
brainmatters-862	43	14	,	,	PUNCT
brainmatters-862	43	15	male	male	ADJ
brainmatters-862	43	16	sex	sex	NOUN
brainmatters-862	43	17	,	,	PUNCT
brainmatters-862	43	18	higher	high	ADJ
brainmatters-862	43	19	tumor	tumor	NOUN
brainmatters-862	43	20	grade	grade	NOUN
brainmatters-862	43	21	,	,	PUNCT
brainmatters-862	43	22	intracranial	intracranial	ADJ
brainmatters-862	43	23	location	location	NOUN
brainmatters-862	43	24	,	,	PUNCT
brainmatters-862	43	25	and	and	CCONJ
brainmatters-862	43	26	failure	failure	NOUN
brainmatters-862	43	27	to	to	PART
brainmatters-862	43	28	undergo	undergo	VERB
brainmatters-862	43	29	surgical	surgical	ADJ
brainmatters-862	43	30	resection	resection	NOUN
brainmatters-862	43	31	.	.	PUNCT
brainmatters-862	44	1	even	even	ADV
brainmatters-862	44	2	with	with	ADP
brainmatters-862	44	3	these	these	DET
brainmatters-862	44	4	findings	finding	NOUN
brainmatters-862	44	5	,	,	PUNCT
brainmatters-862	44	6	the	the	DET
brainmatters-862	44	7	use	use	NOUN
brainmatters-862	44	8	of	of	ADP
brainmatters-862	44	9	the	the	DET
brainmatters-862	44	10	central	central	ADJ
brainmatters-862	44	11	registry	registry	NOUN
brainmatters-862	44	12	does	do	AUX
brainmatters-862	44	13	suggest	suggest	VERB
brainmatters-862	44	14	possible	possible	ADJ
brainmatters-862	44	15	issues	issue	NOUN
brainmatters-862	44	16	with	with	ADP
brainmatters-862	44	17	diagnosis	diagnosis	NOUN
brainmatters-862	44	18	.	.	PUNCT
brainmatters-862	45	1	analysis	analysis	NOUN
brainmatters-862	45	2	of	of	ADP
brainmatters-862	45	3	ependymoma	ependymoma	NOUN
brainmatters-862	45	4	cases	case	NOUN
brainmatters-862	45	5	in	in	ADP
brainmatters-862	45	6	a	a	DET
brainmatters-862	45	7	single	single	ADJ
brainmatters-862	45	8	institution	institution	NOUN
brainmatters-862	45	9	found	find	VERB
brainmatters-862	45	10	that	that	SCONJ
brainmatters-862	45	11	nearly	nearly	ADV
brainmatters-862	45	12	20	20	NUM
brainmatters-862	45	13	%	%	NOUN
brainmatters-862	45	14	of	of	ADP
brainmatters-862	45	15	cases	case	NOUN
brainmatters-862	45	16	had	have	AUX
brainmatters-862	45	17	been	be	AUX
brainmatters-862	45	18	misdiagnosed	misdiagnose	VERB
brainmatters-862	45	19	as	as	ADP
brainmatters-862	45	20	another	another	DET
brainmatters-862	45	21	histological	histological	ADJ
brainmatters-862	45	22	type	type	NOUN
brainmatters-862	45	23	of	of	ADP
brainmatters-862	45	24	neoplasm	neoplasm	NOUN
brainmatters-862	45	25	prior	prior	ADV
brainmatters-862	45	26	to	to	ADP
brainmatters-862	45	27	expert	expert	NOUN
brainmatters-862	45	28	review	review	NOUN
brainmatters-862	45	29	.	.	PUNCT
brainmatters-862	46	1	(	(	PUNCT
brainmatters-862	46	2	wu	wu	PROPN
brainmatters-862	46	3	,	,	PUNCT
brainmatters-862	46	4	2016	2016	NUM
brainmatters-862	46	5	)	)	PUNCT
brainmatters-862	46	6	in	in	ADP
brainmatters-862	46	7	order	order	NOUN
brainmatters-862	46	8	to	to	PART
brainmatters-862	46	9	understand	understand	VERB
brainmatters-862	46	10	how	how	SCONJ
brainmatters-862	46	11	the	the	DET
brainmatters-862	46	12	prognostic	prognostic	ADJ
brainmatters-862	46	13	factors	factor	NOUN
brainmatters-862	46	14	for	for	ADP
brainmatters-862	46	15	pediatric	pediatric	ADJ
brainmatters-862	46	16	patients	patient	NOUN
brainmatters-862	46	17	are	be	AUX
brainmatters-862	46	18	different	different	ADJ
brainmatters-862	46	19	from	from	ADP
brainmatters-862	46	20	those	those	PRON
brainmatters-862	46	21	of	of	ADP
brainmatters-862	46	22	adults	adult	NOUN
brainmatters-862	46	23	,	,	PUNCT
brainmatters-862	46	24	(	(	PUNCT
brainmatters-862	46	25	amirian	amirian	NOUN
brainmatters-862	46	26	et	et	PROPN
brainmatters-862	46	27	al	al	PROPN
brainmatters-862	46	28	,	,	PUNCT
brainmatters-862	46	29	2016	2016	NUM
brainmatters-862	46	30	)	)	PUNCT
brainmatters-862	46	31	the	the	DET
brainmatters-862	46	32	ependymoma	ependymoma	NOUN
brainmatters-862	46	33	cases	case	VERB
brainmatters-862	46	34	from	from	ADP
brainmatters-862	46	35	the	the	DET
brainmatters-862	46	36	seer	seer	NOUN
brainmatters-862	46	37	database	database	NOUN
brainmatters-862	46	38	are	be	AUX
brainmatters-862	46	39	analyzed	analyze	VERB
brainmatters-862	46	40	separately	separately	ADV
brainmatters-862	46	41	for	for	ADP
brainmatters-862	46	42	pediatric	pediatric	ADJ
brainmatters-862	46	43	and	and	CCONJ
brainmatters-862	46	44	adult	adult	NOUN
brainmatters-862	46	45	patients	patient	NOUN
brainmatters-862	46	46	.	.	PUNCT
brainmatters-862	47	1	anaplastic	anaplastic	ADJ
brainmatters-862	47	2	and	and	CCONJ
brainmatters-862	47	3	infratentorial	infratentorial	ADJ
brainmatters-862	47	4	location	location	NOUN
brainmatters-862	47	5	of	of	ADP
brainmatters-862	47	6	tumors	tumor	NOUN
brainmatters-862	47	7	were	be	AUX
brainmatters-862	47	8	associated	associate	VERB
brainmatters-862	47	9	with	with	ADP
brainmatters-862	47	10	increased	increase	VERB
brainmatters-862	47	11	mortality	mortality	NOUN
brainmatters-862	47	12	rate	rate	NOUN
brainmatters-862	47	13	in	in	ADP
brainmatters-862	47	14	pediatric	pediatric	ADJ
brainmatters-862	47	15	cases	case	NOUN
brainmatters-862	47	16	,	,	PUNCT
brainmatters-862	47	17	while	while	SCONJ
brainmatters-862	47	18	a	a	DET
brainmatters-862	47	19	supratentorial	supratentorial	ADJ
brainmatters-862	47	20	location	location	NOUN
brainmatters-862	47	21	was	be	AUX
brainmatters-862	47	22	associated	associate	VERB
brainmatters-862	47	23	with	with	ADP
brainmatters-862	47	24	higher	high	ADJ
brainmatters-862	47	25	mortality	mortality	NOUN
brainmatters-862	47	26	rate	rate	NOUN
brainmatters-862	47	27	in	in	ADP
brainmatters-862	47	28	adult	adult	NOUN
brainmatters-862	47	29	patients	patient	NOUN
brainmatters-862	47	30	.	.	PUNCT
brainmatters-862	48	1	surgical	surgical	ADJ
brainmatters-862	48	2	resection	resection	NOUN
brainmatters-862	48	3	proved	prove	VERB
brainmatters-862	48	4	to	to	PART
brainmatters-862	48	5	be	be	AUX
brainmatters-862	48	6	beneficial	beneficial	ADJ
brainmatters-862	48	7	for	for	ADP
brainmatters-862	48	8	both	both	CCONJ
brainmatters-862	48	9	pediatric	pediatric	ADJ
brainmatters-862	48	10	and	and	CCONJ
brainmatters-862	48	11	adult	adult	NOUN
brainmatters-862	48	12	patients	patient	NOUN
brainmatters-862	48	13	.	.	PUNCT
brainmatters-862	49	1	(	(	PUNCT
brainmatters-862	49	2	wu	wu	PROPN
brainmatters-862	49	3	,	,	PUNCT
brainmatters-862	49	4	2016	2016	NUM
brainmatters-862	49	5	)	)	PUNCT
brainmatters-862	49	6	the	the	DET
brainmatters-862	49	7	unfavorable	unfavorable	ADJ
brainmatters-862	49	8	prognostic	prognostic	ADJ
brainmatters-862	49	9	impact	impact	NOUN
brainmatters-862	49	10	of	of	ADP
brainmatters-862	49	11	a	a	DET
brainmatters-862	49	12	supratentorial	supratentorial	ADJ
brainmatters-862	49	13	location	location	NOUN
brainmatters-862	49	14	was	be	AUX
brainmatters-862	49	15	shown	show	VERB
brainmatters-862	49	16	by	by	ADP
brainmatters-862	49	17	analysis	analysis	NOUN
brainmatters-862	49	18	from	from	ADP
brainmatters-862	49	19	a	a	DET
brainmatters-862	49	20	study	study	NOUN
brainmatters-862	49	21	involving	involve	VERB
brainmatters-862	49	22	seventy	seventy	NUM
brainmatters-862	49	23	patients	patient	NOUN
brainmatters-862	49	24	aged	age	VERB
brainmatters-862	49	25	older	old	ADJ
brainmatters-862	49	26	than	than	ADP
brainmatters-862	49	27	17	17	NUM
brainmatters-862	49	28	years	year	NOUN
brainmatters-862	49	29	.	.	PUNCT
brainmatters-862	50	1	however	however	ADV
brainmatters-862	50	2	,	,	PUNCT
brainmatters-862	50	3	only	only	ADV
brainmatters-862	50	4	older	old	ADJ
brainmatters-862	50	5	age	age	NOUN
brainmatters-862	50	6	,	,	PUNCT
brainmatters-862	50	7	and	and	CCONJ
brainmatters-862	50	8	not	not	PART
brainmatters-862	50	9	supratentorial	supratentorial	ADJ
brainmatters-862	50	10	location	location	NOUN
brainmatters-862	50	11	,	,	PUNCT
brainmatters-862	50	12	was	be	AUX
brainmatters-862	50	13	found	find	VERB
brainmatters-862	50	14	to	to	PART
brainmatters-862	50	15	be	be	AUX
brainmatters-862	50	16	an	an	DET
brainmatters-862	50	17	unfavorable	unfavorable	ADJ
brainmatters-862	50	18	prognostic	prognostic	ADJ
brainmatters-862	50	19	factor	factor	NOUN
brainmatters-862	50	20	by	by	ADP
brainmatters-862	50	21	multivariate	multivariate	NOUN
brainmatters-862	50	22	analysis	analysis	NOUN
brainmatters-862	50	23	from	from	ADP
brainmatters-862	50	24	the	the	DET
brainmatters-862	50	25	study	study	NOUN
brainmatters-862	50	26	.	.	PUNCT
brainmatters-862	51	1	(	(	PUNCT
brainmatters-862	51	2	wu	wu	PROPN
brainmatters-862	51	3	,	,	PUNCT
brainmatters-862	51	4	2016	2016	NUM
brainmatters-862	51	5	)	)	PUNCT
brainmatters-862	51	6	a	a	DET
brainmatters-862	51	7	single	single	ADJ
brainmatters-862	51	8	institution	institution	NOUN
brainmatters-862	51	9	study	study	NOUN
brainmatters-862	51	10	of	of	ADP
brainmatters-862	51	11	123	123	NUM
brainmatters-862	51	12	adult	adult	NOUN
brainmatters-862	51	13	ependymoma	ependymoma	NOUN
brainmatters-862	51	14	patients	patient	NOUN
brainmatters-862	51	15	was	be	AUX
brainmatters-862	51	16	conducted	conduct	VERB
brainmatters-862	51	17	at	at	ADP
brainmatters-862	51	18	the	the	DET
brainmatters-862	51	19	university	university	PROPN
brainmatters-862	51	20	of	of	ADP
brainmatters-862	51	21	texas	texas	PROPN
brainmatters-862	51	22	md	md	PROPN
brainmatters-862	51	23	anderson	anderson	PROPN
brainmatters-862	51	24	cancer	cancer	PROPN
brainmatters-862	51	25	center	center	PROPN
brainmatters-862	51	26	.	.	PUNCT
brainmatters-862	52	1	forty	forty	NUM
brainmatters-862	52	2	patients	patient	NOUN
brainmatters-862	52	3	had	have	VERB
brainmatters-862	52	4	tumors	tumor	NOUN
brainmatters-862	52	5	in	in	ADP
brainmatters-862	52	6	the	the	DET
brainmatters-862	52	7	brain	brain	NOUN
brainmatters-862	52	8	,	,	PUNCT
brainmatters-862	52	9	80	80	NUM
brainmatters-862	52	10	in	in	ADP
brainmatters-862	52	11	the	the	DET
brainmatters-862	52	12	spinal	spinal	NOUN
brainmatters-862	52	13	cord	cord	NOUN
brainmatters-862	52	14	,	,	PUNCT
brainmatters-862	52	15	and	and	CCONJ
brainmatters-862	52	16	3	3	NUM
brainmatters-862	52	17	at	at	ADP
brainmatters-862	52	18	both	both	DET
brainmatters-862	52	19	locations	location	NOUN
brainmatters-862	52	20	.	.	PUNCT
brainmatters-862	53	1	although	although	SCONJ
brainmatters-862	53	2	most	most	ADJ
brainmatters-862	53	3	of	of	ADP
brainmatters-862	53	4	the	the	DET
brainmatters-862	53	5	tumors	tumor	NOUN
brainmatters-862	53	6	were	be	AUX
brainmatters-862	53	7	grade	grade	NOUN
brainmatters-862	53	8	i	i	PROPN
brainmatters-862	53	9	or	or	CCONJ
brainmatters-862	53	10	ii	ii	PROPN
brainmatters-862	53	11	,	,	PUNCT
brainmatters-862	53	12	the	the	DET
brainmatters-862	53	13	study	study	NOUN
brainmatters-862	53	14	showed	show	VERB
brainmatters-862	53	15	that	that	SCONJ
brainmatters-862	53	16	brain	brain	NOUN
brainmatters-862	53	17	location	location	NOUN
brainmatters-862	53	18	(	(	PUNCT
brainmatters-862	53	19	versus	versus	ADP
brainmatters-862	53	20	spinal	spinal	ADJ
brainmatters-862	53	21	cord	cord	NOUN
brainmatters-862	53	22	)	)	PUNCT
brainmatters-862	53	23	and	and	CCONJ
brainmatters-862	53	24	tumor	tumor	NOUN
brainmatters-862	53	25	anaplasia	anaplasia	PROPN
brainmatters-862	53	26	were	be	AUX
brainmatters-862	53	27	associated	associate	VERB
brainmatters-862	53	28	with	with	ADP
brainmatters-862	53	29	a	a	DET
brainmatters-862	53	30	worse	bad	ADJ
brainmatters-862	53	31	outcome	outcome	NOUN
brainmatters-862	53	32	in	in	ADP
brainmatters-862	53	33	adults	adult	NOUN
brainmatters-862	53	34	measured	measure	VERB
brainmatters-862	53	35	by	by	ADP
brainmatters-862	53	36	both	both	DET
brainmatters-862	53	37	overall	overall	ADJ
brainmatters-862	53	38	survival	survival	NOUN
brainmatters-862	53	39	(	(	PUNCT
brainmatters-862	53	40	os	os	NOUN
brainmatters-862	53	41	)	)	PUNCT
brainmatters-862	53	42	and	and	CCONJ
brainmatters-862	53	43	progression	progression	NOUN
brainmatters-862	53	44	-	-	PUNCT
brainmatters-862	53	45	free	free	ADJ
brainmatters-862	53	46	survival	survival	NOUN
brainmatters-862	53	47	(	(	PUNCT
brainmatters-862	53	48	pfs	pfs	PROPN
brainmatters-862	53	49	)	)	PUNCT
brainmatters-862	53	50	(	(	PUNCT
brainmatters-862	53	51	wu	wu	PROPN
brainmatters-862	53	52	2016	2016	NUM
brainmatters-862	53	53	)	)	PUNCT
brainmatters-862	53	54	.	.	PUNCT
brainmatters-862	54	1	ependymal	ependymal	ADJ
brainmatters-862	54	2	tumors	tumor	NOUN
brainmatters-862	54	3	have	have	VERB
brainmatters-862	54	4	a	a	DET
brainmatters-862	54	5	rare	rare	ADJ
brainmatters-862	54	6	occurrence	occurrence	NOUN
brainmatters-862	54	7	,	,	PUNCT
brainmatters-862	54	8	comprising	comprise	VERB
brainmatters-862	54	9	1.7	1.7	NUM
brainmatters-862	54	10	%	%	NOUN
brainmatters-862	54	11	of	of	ADP
brainmatters-862	54	12	all	all	DET
brainmatters-862	54	13	brain	brain	NOUN
brainmatters-862	54	14	tumors	tumor	NOUN
brainmatters-862	54	15	,	,	PUNCT
brainmatters-862	54	16	as	as	SCONJ
brainmatters-862	54	17	reported	report	VERB
brainmatters-862	54	18	in	in	ADP
brainmatters-862	54	19	the	the	DET
brainmatters-862	54	20	cbtrus	cbtrus	NOUN
brainmatters-862	54	21	statistical	statistical	ADJ
brainmatters-862	54	22	report	report	NOUN
brainmatters-862	54	23	.	.	PUNCT
brainmatters-862	55	1	it	it	PRON
brainmatters-862	55	2	has	have	AUX
brainmatters-862	55	3	been	be	AUX
brainmatters-862	55	4	difficult	difficult	ADJ
brainmatters-862	55	5	to	to	PART
brainmatters-862	55	6	find	find	VERB
brainmatters-862	55	7	an	an	DET
brainmatters-862	55	8	effective	effective	ADJ
brainmatters-862	55	9	treatment	treatment	NOUN
brainmatters-862	55	10	for	for	ADP
brainmatters-862	55	11	the	the	DET
brainmatters-862	55	12	disease	disease	NOUN
brainmatters-862	55	13	due	due	ADP
brainmatters-862	55	14	to	to	ADP
brainmatters-862	55	15	the	the	DET
brainmatters-862	55	16	low	low	ADJ
brainmatters-862	55	17	percentage	percentage	NOUN
brainmatters-862	55	18	of	of	ADP
brainmatters-862	55	19	occurrence	occurrence	NOUN
brainmatters-862	55	20	of	of	ADP
brainmatters-862	55	21	these	these	DET
brainmatters-862	55	22	tumors	tumor	NOUN
brainmatters-862	55	23	(	(	PUNCT
brainmatters-862	55	24	zamora	zamora	PROPN
brainmatters-862	55	25	,	,	PUNCT
brainmatters-862	55	26	2020	2020	NUM
brainmatters-862	55	27	)	)	PUNCT
brainmatters-862	55	28	.	.	PUNCT
brainmatters-862	56	1	studies	study	NOUN
brainmatters-862	56	2	have	have	AUX
brainmatters-862	56	3	shown	show	VERB
brainmatters-862	56	4	an	an	DET
brainmatters-862	56	5	improved	improved	ADJ
brainmatters-862	56	6	survival	survival	NOUN
brainmatters-862	56	7	for	for	ADP
brainmatters-862	56	8	patients	patient	NOUN
brainmatters-862	56	9	who	who	PRON
brainmatters-862	56	10	undergo	undergo	VERB
brainmatters-862	56	11	resection	resection	NOUN
brainmatters-862	56	12	with	with	ADP
brainmatters-862	56	13	adjuvant	adjuvant	ADJ
brainmatters-862	56	14	radiation	radiation	NOUN
brainmatters-862	56	15	therapy	therapy	NOUN
brainmatters-862	56	16	.	.	PUNCT
brainmatters-862	57	1	there	there	PRON
brainmatters-862	57	2	is	be	VERB
brainmatters-862	57	3	minimal	minimal	ADJ
brainmatters-862	57	4	and	and	CCONJ
brainmatters-862	57	5	limited	limited	ADJ
brainmatters-862	57	6	evidence	evidence	NOUN
brainmatters-862	57	7	supporting	support	VERB
brainmatters-862	57	8	chemotherapy	chemotherapy	NOUN
brainmatters-862	57	9	for	for	ADP
brainmatters-862	57	10	adult	adult	NOUN
brainmatters-862	57	11	ependymomas	ependymomas	PROPN
brainmatters-862	57	12	(	(	PUNCT
brainmatters-862	57	13	zamora	zamora	PROPN
brainmatters-862	57	14	,	,	PUNCT
brainmatters-862	57	15	2020	2020	NUM
brainmatters-862	57	16	)	)	PUNCT
brainmatters-862	57	17	.	.	PUNCT
brainmatters-862	58	1	currently	currently	ADV
brainmatters-862	58	2	none	none	NOUN
brainmatters-862	58	3	of	of	ADP
brainmatters-862	58	4	the	the	DET
brainmatters-862	58	5	established	establish	VERB
brainmatters-862	58	6	guidelines	guideline	NOUN
brainmatters-862	58	7	use	use	VERB
brainmatters-862	58	8	the	the	DET
brainmatters-862	58	9	molecular	molecular	ADJ
brainmatters-862	58	10	subgroups	subgroup	NOUN
brainmatters-862	58	11	to	to	PART
brainmatters-862	58	12	guide	guide	VERB
brainmatters-862	58	13	treatment	treatment	NOUN
brainmatters-862	58	14	of	of	ADP
brainmatters-862	58	15	ependymoma	ependymoma	NOUN
brainmatters-862	58	16	.	.	PUNCT
brainmatters-862	59	1	the	the	DET
brainmatters-862	59	2	current	current	ADJ
brainmatters-862	59	3	consensus	consensus	NOUN
brainmatters-862	59	4	recommends	recommend	VERB
brainmatters-862	59	5	that	that	SCONJ
brainmatters-862	59	6	patients	patient	NOUN
brainmatters-862	59	7	with	with	ADP
brainmatters-862	59	8	pf	pf	NOUN
brainmatters-862	59	9	-	-	PUNCT
brainmatters-862	59	10	epn	epn	NOUN
brainmatters-862	59	11	-	-	PUNCT
brainmatters-862	59	12	a	a	DET
brainmatters-862	59	13	positive	positive	ADJ
brainmatters-862	59	14	ependymoma	ependymoma	NOUN
brainmatters-862	59	15	,	,	PUNCT
brainmatters-862	59	16	who	who	PRON
brainmatters-862	59	17	are	be	AUX
brainmatters-862	59	18	older	old	ADJ
brainmatters-862	59	19	than	than	ADP
brainmatters-862	59	20	12	12	NUM
brainmatters-862	59	21	months	month	NOUN
brainmatters-862	59	22	undergo	undergo	VERB
brainmatters-862	59	23	maximal	maximal	ADJ
brainmatters-862	59	24	safe	safe	ADJ
brainmatters-862	59	25	micro	micro	ADJ
brainmatters-862	59	26	-	-	ADJ
brainmatters-862	59	27	neurosurgical	neurosurgical	ADJ
brainmatters-862	59	28	removal	removal	NOUN
brainmatters-862	59	29	in	in	ADP
brainmatters-862	59	30	addition	addition	NOUN
brainmatters-862	59	31	to	to	ADP
brainmatters-862	59	32	local	local	ADJ
brainmatters-862	59	33	radiotherapy	radiotherapy	NOUN
brainmatters-862	59	34	.	.	PUNCT
brainmatters-862	60	1	(	(	PUNCT
brainmatters-862	60	2	zamora	zamora	PROPN
brainmatters-862	60	3	,	,	PUNCT
brainmatters-862	60	4	2020	2020	NUM
brainmatters-862	60	5	)	)	PUNCT
brainmatters-862	60	6	.	.	PUNCT
brainmatters-862	61	1	for	for	ADP
brainmatters-862	61	2	intracranial	intracranial	ADJ
brainmatters-862	61	3	ependymomas	ependymoma	NOUN
brainmatters-862	61	4	,	,	PUNCT
brainmatters-862	61	5	surgery	surgery	NOUN
brainmatters-862	61	6	is	be	AUX
brainmatters-862	61	7	the	the	DET
brainmatters-862	61	8	main	main	ADJ
brainmatters-862	61	9	treatment	treatment	NOUN
brainmatters-862	61	10	.	.	PUNCT
brainmatters-862	62	1	complete	complete	ADJ
brainmatters-862	62	2	resection	resection	NOUN
brainmatters-862	62	3	without	without	ADP
brainmatters-862	62	4	residual	residual	ADJ
brainmatters-862	62	5	disease	disease	NOUN
brainmatters-862	62	6	has	have	AUX
brainmatters-862	62	7	presented	present	VERB
brainmatters-862	62	8	better	well	ADJ
brainmatters-862	62	9	clinical	clinical	ADJ
brainmatters-862	62	10	outcomes	outcome	NOUN
brainmatters-862	62	11	and	and	CCONJ
brainmatters-862	62	12	better	well	ADJ
brainmatters-862	62	13	overall	overall	ADJ
brainmatters-862	62	14	survival	survival	NOUN
brainmatters-862	62	15	rate	rate	NOUN
brainmatters-862	62	16	than	than	ADP
brainmatters-862	62	17	partial	partial	ADJ
brainmatters-862	62	18	resection	resection	NOUN
brainmatters-862	62	19	.	.	PUNCT
brainmatters-862	63	1	(	(	PUNCT
brainmatters-862	63	2	zamora	zamora	PROPN
brainmatters-862	63	3	,	,	PUNCT
brainmatters-862	63	4	2020	2020	NUM
brainmatters-862	63	5	)	)	PUNCT
brainmatters-862	63	6	as	as	SCONJ
brainmatters-862	63	7	discussed	discuss	VERB
brainmatters-862	63	8	previously	previously	ADV
brainmatters-862	63	9	,	,	PUNCT
brainmatters-862	63	10	there	there	PRON
brainmatters-862	63	11	is	be	VERB
brainmatters-862	63	12	insufficient	insufficient	ADJ
brainmatters-862	63	13	evidence	evidence	NOUN
brainmatters-862	63	14	to	to	PART
brainmatters-862	63	15	support	support	VERB
brainmatters-862	63	16	the	the	DET
brainmatters-862	63	17	use	use	NOUN
brainmatters-862	63	18	of	of	ADP
brainmatters-862	63	19	chemotherapy	chemotherapy	NOUN
brainmatters-862	63	20	.	.	PUNCT
brainmatters-862	64	1	patients	patient	NOUN
brainmatters-862	64	2	who	who	PRON
brainmatters-862	64	3	are	be	AUX
brainmatters-862	64	4	long	long	ADJ
brainmatters-862	64	5	term	term	NOUN
brainmatters-862	64	6	survivors	survivor	NOUN
brainmatters-862	64	7	from	from	ADP
brainmatters-862	64	8	central	central	ADJ
brainmatters-862	64	9	nervous	nervous	ADJ
brainmatters-862	64	10	system	system	NOUN
brainmatters-862	64	11	tumors	tumor	NOUN
brainmatters-862	64	12	present	present	VERB
brainmatters-862	64	13	a	a	DET
brainmatters-862	64	14	diverse	diverse	ADJ
brainmatters-862	64	15	array	array	NOUN
brainmatters-862	64	16	of	of	ADP
brainmatters-862	64	17	complications	complication	NOUN
brainmatters-862	64	18	,	,	PUNCT
brainmatters-862	64	19	including	include	VERB
brainmatters-862	64	20	neurological	neurological	ADJ
brainmatters-862	64	21	deficits	deficit	NOUN
brainmatters-862	64	22	,	,	PUNCT
brainmatters-862	64	23	cognitive	cognitive	ADJ
brainmatters-862	64	24	limitations	limitation	NOUN
brainmatters-862	64	25	,	,	PUNCT
brainmatters-862	64	26	hearing	hear	VERB
brainmatters-862	64	27	loss	loss	NOUN
brainmatters-862	64	28	,	,	PUNCT
brainmatters-862	64	29	endocrine	endocrine	NOUN
brainmatters-862	64	30	and	and	CCONJ
brainmatters-862	64	31	growth	growth	NOUN
brainmatters-862	64	32	abnormalities	abnormality	NOUN
brainmatters-862	64	33	,	,	PUNCT
brainmatters-862	64	34	and	and	CCONJ
brainmatters-862	64	35	secondary	secondary	ADJ
brainmatters-862	64	36	malignancies	malignancy	NOUN
brainmatters-862	64	37	.	.	PUNCT
brainmatters-862	65	1	adult	adult	NOUN
brainmatters-862	65	2	patients	patient	NOUN
brainmatters-862	65	3	may	may	AUX
brainmatters-862	65	4	present	present	VERB
brainmatters-862	65	5	long	long	ADJ
brainmatters-862	65	6	term	term	NOUN
brainmatters-862	65	7	complications	complication	NOUN
brainmatters-862	65	8	,	,	PUNCT
brainmatters-862	65	9	most	most	ADV
brainmatters-862	65	10	commonly	commonly	ADV
brainmatters-862	65	11	fatigue	fatigue	NOUN
brainmatters-862	65	12	,	,	PUNCT
brainmatters-862	65	13	numbness	numbness	NOUN
brainmatters-862	65	14	and	and	CCONJ
brainmatters-862	65	15	tingling	tingling	NOUN
brainmatters-862	65	16	,	,	PUNCT
brainmatters-862	65	17	pain	pain	NOUN
brainmatters-862	65	18	,	,	PUNCT
brainmatters-862	65	19	and	and	CCONJ
brainmatters-862	65	20	disturbed	disturbed	ADJ
brainmatters-862	65	21	sleep	sleep	NOUN
brainmatters-862	65	22	.	.	PUNCT
brainmatters-862	66	1	(	(	PUNCT
brainmatters-862	66	2	zamora	zamora	PROPN
brainmatters-862	66	3	,	,	PUNCT
brainmatters-862	66	4	2020)childhood	2020)childhood	NUM
brainmatters-862	66	5	intracranial	intracranial	ADJ
brainmatters-862	66	6	ependymoma	ependymoma	NOUN
brainmatters-862	66	7	has	have	VERB
brainmatters-862	66	8	a	a	DET
brainmatters-862	66	9	poor	poor	ADJ
brainmatters-862	66	10	prognosis	prognosis	NOUN
brainmatters-862	66	11	,	,	PUNCT
brainmatters-862	66	12	especially	especially	ADV
brainmatters-862	66	13	in	in	ADP
brainmatters-862	66	14	young	young	ADJ
brainmatters-862	66	15	children	child	NOUN
brainmatters-862	66	16	when	when	SCONJ
brainmatters-862	66	17	a	a	DET
brainmatters-862	66	18	gross	gross	ADJ
brainmatters-862	66	19	total	total	ADJ
brainmatters-862	66	20	resection	resection	NOUN
brainmatters-862	66	21	can	can	AUX
brainmatters-862	66	22	not	not	PART
brainmatters-862	66	23	be	be	AUX
brainmatters-862	66	24	performed	perform	VERB
brainmatters-862	66	25	.	.	PUNCT
brainmatters-862	67	1	even	even	ADV
brainmatters-862	67	2	without	without	ADP
brainmatters-862	67	3	radiologically	radiologically	ADV
brainmatters-862	67	4	proven	prove	VERB
brainmatters-862	67	5	residuum	residuum	NOUN
brainmatters-862	67	6	,	,	PUNCT
brainmatters-862	67	7	around	around	ADV
brainmatters-862	67	8	two	two	NUM
brainmatters-862	67	9	-	-	PUNCT
brainmatters-862	67	10	thirds	third	NOUN
brainmatters-862	67	11	of	of	ADP
brainmatters-862	67	12	these	these	DET
brainmatters-862	67	13	young	young	ADJ
brainmatters-862	67	14	children	child	NOUN
brainmatters-862	67	15	will	will	AUX
brainmatters-862	67	16	have	have	VERB
brainmatters-862	67	17	a	a	DET
brainmatters-862	67	18	relapse	relapse	NOUN
brainmatters-862	67	19	.	.	PUNCT
brainmatters-862	68	1	(	(	PUNCT
brainmatters-862	68	2	grill	grill	NOUN
brainmatters-862	68	3	,	,	PUNCT
brainmatters-862	68	4	2003	2003	NUM
brainmatters-862	68	5	)	)	PUNCT
brainmatters-862	68	6	.	.	PUNCT
brainmatters-862	69	1	adjuvant	adjuvant	ADJ
brainmatters-862	69	2	therapy	therapy	NOUN
brainmatters-862	69	3	is	be	AUX
brainmatters-862	69	4	necessary	necessary	ADJ
brainmatters-862	69	5	for	for	ADP
brainmatters-862	69	6	most	most	ADJ
brainmatters-862	69	7	,	,	PUNCT
brainmatters-862	69	8	if	if	SCONJ
brainmatters-862	69	9	not	not	PART
brainmatters-862	69	10	all	all	PRON
brainmatters-862	69	11	,	,	PUNCT
brainmatters-862	69	12	patients	patient	NOUN
brainmatters-862	69	13	.	.	PUNCT
brainmatters-862	70	1	craniospinal	craniospinal	ADJ
brainmatters-862	70	2	irradiation	irradiation	NOUN
brainmatters-862	70	3	combined	combine	VERB
brainmatters-862	70	4	with	with	ADP
brainmatters-862	70	5	posterior	posterior	ADJ
brainmatters-862	70	6	fossa	fossa	ADJ
brainmatters-862	70	7	boost	boost	NOUN
brainmatters-862	70	8	has	have	VERB
brainmatters-862	70	9	deleterious	deleterious	ADJ
brainmatters-862	70	10	effects	effect	NOUN
brainmatters-862	70	11	on	on	ADP
brainmatters-862	70	12	cognition	cognition	NOUN
brainmatters-862	70	13	.	.	PUNCT
brainmatters-862	71	1	pediatric	pediatric	ADJ
brainmatters-862	71	2	oncology	oncology	NOUN
brainmatters-862	71	3	teams	team	NOUN
brainmatters-862	71	4	have	have	AUX
brainmatters-862	71	5	tried	try	VERB
brainmatters-862	71	6	to	to	PART
brainmatters-862	71	7	use	use	VERB
brainmatters-862	71	8	chemotherapy	chemotherapy	NOUN
brainmatters-862	71	9	to	to	PART
brainmatters-862	71	10	avoid	avoid	VERB
brainmatters-862	71	11	irradiation	irradiation	NOUN
brainmatters-862	71	12	and	and	CCONJ
brainmatters-862	71	13	reduce	reduce	VERB
brainmatters-862	71	14	irradiation	irradiation	NOUN
brainmatters-862	71	15	fields	field	NOUN
brainmatters-862	71	16	to	to	ADP
brainmatters-862	71	17	the	the	DET
brainmatters-862	71	18	tumor	tumor	NOUN
brainmatters-862	71	19	bed	bed	NOUN
brainmatters-862	71	20	without	without	ADP
brainmatters-862	71	21	altering	alter	VERB
brainmatters-862	71	22	the	the	DET
brainmatters-862	71	23	prognosis	prognosis	NOUN
brainmatters-862	71	24	.	.	PUNCT
brainmatters-862	72	1	cisplatin	cisplatin	NOUN
brainmatters-862	72	2	,	,	PUNCT
brainmatters-862	72	3	at	at	ADP
brainmatters-862	72	4	a	a	DET
brainmatters-862	72	5	dose	dose	NOUN
brainmatters-862	72	6	of	of	ADP
brainmatters-862	72	7	120	120	NUM
brainmatters-862	72	8	mg	mg	NOUN
brainmatters-862	72	9	is	be	AUX
brainmatters-862	72	10	the	the	DET
brainmatters-862	72	11	only	only	ADJ
brainmatters-862	72	12	single	single	ADJ
brainmatters-862	72	13	agent	agent	NOUN
brainmatters-862	72	14	that	that	PRON
brainmatters-862	72	15	has	have	AUX
brainmatters-862	72	16	reproducibly	reproducibly	ADV
brainmatters-862	72	17	shown	show	VERB
brainmatters-862	72	18	some	some	DET
brainmatters-862	72	19	efficacy	efficacy	NOUN
brainmatters-862	72	20	in	in	ADP
brainmatters-862	72	21	ependymoma	ependymoma	NOUN
brainmatters-862	72	22	.	.	PUNCT
brainmatters-862	73	1	(	(	PUNCT
brainmatters-862	73	2	grill	grill	NOUN
brainmatters-862	73	3	,	,	PUNCT
brainmatters-862	73	4	2003	2003	NUM
brainmatters-862	73	5	)	)	PUNCT
brainmatters-862	73	6	despite	despite	SCONJ
brainmatters-862	73	7	some	some	DET
brainmatters-862	73	8	combinations	combination	NOUN
brainmatters-862	73	9	showing	show	VERB
brainmatters-862	73	10	efficacy	efficacy	NOUN
brainmatters-862	73	11	in	in	ADP
brainmatters-862	73	12	the	the	DET
brainmatters-862	73	13	adjuvant	adjuvant	ADJ
brainmatters-862	73	14	setting	setting	NOUN
brainmatters-862	73	15	,	,	PUNCT
brainmatters-862	73	16	childhood	childhood	PROPN
brainmatters-862	73	17	intracranial	intracranial	ADJ
brainmatters-862	73	18	ependymomas	ependymoma	NOUN
brainmatters-862	73	19	can	can	AUX
brainmatters-862	73	20	be	be	AUX
brainmatters-862	73	21	considered	consider	VERB
brainmatters-862	73	22	chemo	chemo	NOUN
brainmatters-862	73	23	resistant	resistant	ADJ
brainmatters-862	73	24	.	.	PUNCT
brainmatters-862	74	1	the	the	DET
brainmatters-862	74	2	overexpression	overexpression	NOUN
brainmatters-862	74	3	of	of	ADP
brainmatters-862	74	4	the	the	DET
brainmatters-862	74	5	multidrug	multidrug	NOUN
brainmatters-862	74	6	resistance-1	resistance-1	NUM
brainmatters-862	74	7	gene	gene	NOUN
brainmatters-862	74	8	and	and	CCONJ
brainmatters-862	74	9	the	the	DET
brainmatters-862	74	10	06	06	NUM
brainmatters-862	74	11	-	-	PUNCT
brainmatters-862	74	12	methylguanine	methylguanine	NOUN
brainmatters-862	74	13	-	-	PUNCT
brainmatters-862	74	14	dna	dna	NOUN
brainmatters-862	74	15	methyltransferase	methyltransferase	NOUN
brainmatters-862	74	16	have	have	AUX
brainmatters-862	74	17	been	be	AUX
brainmatters-862	74	18	implicated	implicate	VERB
brainmatters-862	74	19	as	as	ADP
brainmatters-862	74	20	possible	possible	ADJ
brainmatters-862	74	21	mechanisms	mechanism	NOUN
brainmatters-862	74	22	for	for	ADP
brainmatters-862	74	23	this	this	DET
brainmatters-862	74	24	phenomenon	phenomenon	NOUN
brainmatters-862	74	25	.	.	PUNCT
brainmatters-862	75	1	as	as	SCONJ
brainmatters-862	75	2	the	the	DET
brainmatters-862	75	3	use	use	NOUN
brainmatters-862	75	4	of	of	ADP
brainmatters-862	75	5	chemotherapy	chemotherapy	NOUN
brainmatters-862	75	6	with	with	ADP
brainmatters-862	75	7	current	current	ADJ
brainmatters-862	75	8	agents	agent	NOUN
brainmatters-862	75	9	is	be	AUX
brainmatters-862	75	10	questionable	questionable	ADJ
brainmatters-862	75	11	,	,	PUNCT
brainmatters-862	75	12	phase	phase	NOUN
brainmatters-862	75	13	ii	ii	NUM
brainmatters-862	75	14	studies	study	NOUN
brainmatters-862	75	15	with	with	ADP
brainmatters-862	75	16	new	new	ADJ
brainmatters-862	75	17	agents	agent	NOUN
brainmatters-862	75	18	and	and	CCONJ
brainmatters-862	75	19	combinations	combination	NOUN
brainmatters-862	75	20	become	become	VERB
brainmatters-862	75	21	necessary	necessary	ADJ
brainmatters-862	75	22	.	.	PUNCT
brainmatters-862	76	1	(	(	PUNCT
brainmatters-862	76	2	grill	grill	NOUN
brainmatters-862	76	3	,	,	PUNCT
brainmatters-862	76	4	2003	2003	NUM
brainmatters-862	76	5	)	)	PUNCT
brainmatters-862	76	6	since	since	SCONJ
brainmatters-862	76	7	the	the	DET
brainmatters-862	76	8	main	main	ADJ
brainmatters-862	76	9	problem	problem	NOUN
brainmatters-862	76	10	of	of	ADP
brainmatters-862	76	11	this	this	DET
brainmatters-862	76	12	disease	disease	NOUN
brainmatters-862	76	13	is	be	AUX
brainmatters-862	76	14	local	local	ADJ
brainmatters-862	76	15	relapse	relapse	NOUN
brainmatters-862	76	16	,	,	PUNCT
brainmatters-862	76	17	it	it	PRON
brainmatters-862	76	18	may	may	AUX
brainmatters-862	76	19	not	not	PART
brainmatters-862	76	20	be	be	AUX
brainmatters-862	76	21	necessary	necessary	ADJ
brainmatters-862	76	22	to	to	PART
brainmatters-862	76	23	irradiate	irradiate	VERB
brainmatters-862	76	24	the	the	DET
brainmatters-862	76	25	whole	whole	ADJ
brainmatters-862	76	26	posterior	posterior	ADJ
brainmatters-862	76	27	fossa	fossa	NOUN
brainmatters-862	76	28	region	region	NOUN
brainmatters-862	76	29	.	.	PUNCT
brainmatters-862	77	1	however	however	ADV
brainmatters-862	77	2	,	,	PUNCT
brainmatters-862	77	3	local	local	ADJ
brainmatters-862	77	4	control	control	NOUN
brainmatters-862	77	5	of	of	ADP
brainmatters-862	77	6	the	the	DET
brainmatters-862	77	7	disease	disease	NOUN
brainmatters-862	77	8	by	by	ADP
brainmatters-862	77	9	irradiation	irradiation	NOUN
brainmatters-862	77	10	must	must	AUX
brainmatters-862	77	11	be	be	AUX
brainmatters-862	77	12	improved	improve	VERB
brainmatters-862	77	13	.	.	PUNCT
brainmatters-862	78	1	in	in	ADP
brainmatters-862	78	2	this	this	DET
brainmatters-862	78	3	respect	respect	NOUN
brainmatters-862	78	4	,	,	PUNCT
brainmatters-862	78	5	hyperfractionation	hyperfractionation	NOUN
brainmatters-862	78	6	or	or	CCONJ
brainmatters-862	78	7	radio	radio	NOUN
brainmatters-862	78	8	sensitizers	sensitizer	NOUN
brainmatters-862	78	9	may	may	AUX
brainmatters-862	78	10	be	be	AUX
brainmatters-862	78	11	valuable	valuable	ADJ
brainmatters-862	78	12	therapeutic	therapeutic	ADJ
brainmatters-862	78	13	options	option	NOUN
brainmatters-862	78	14	.	.	PUNCT
brainmatters-862	79	1	the	the	DET
brainmatters-862	79	2	treatment	treatment	NOUN
brainmatters-862	79	3	of	of	ADP
brainmatters-862	79	4	children	child	NOUN
brainmatters-862	79	5	with	with	ADP
brainmatters-862	79	6	ependymoma	ependymoma	NOUN
brainmatters-862	79	7	is	be	AUX
brainmatters-862	79	8	a	a	DET
brainmatters-862	79	9	challenge	challenge	NOUN
brainmatters-862	79	10	for	for	ADP
brainmatters-862	79	11	all	all	DET
brainmatters-862	79	12	caregivers	caregiver	NOUN
brainmatters-862	79	13	.	.	PUNCT
brainmatters-862	80	1	there	there	PRON
brainmatters-862	80	2	is	be	VERB
brainmatters-862	80	3	no	no	DET
brainmatters-862	80	4	doubt	doubt	NOUN
brainmatters-862	80	5	that	that	SCONJ
brainmatters-862	80	6	any	any	DET
brainmatters-862	80	7	possible	possible	ADJ
brainmatters-862	80	8	improvement	improvement	NOUN
brainmatters-862	80	9	in	in	ADP
brainmatters-862	80	10	the	the	DET
brainmatters-862	80	11	management	management	NOUN
brainmatters-862	80	12	of	of	ADP
brainmatters-862	80	13	this	this	DET
brainmatters-862	80	14	rare	rare	ADJ
brainmatters-862	80	15	tumor	tumor	NOUN
brainmatters-862	80	16	will	will	AUX
brainmatters-862	80	17	only	only	ADV
brainmatters-862	80	18	be	be	AUX
brainmatters-862	80	19	the	the	DET
brainmatters-862	80	20	result	result	NOUN
brainmatters-862	80	21	of	of	ADP
brainmatters-862	80	22	well	well	ADV
brainmatters-862	80	23	-	-	PUNCT
brainmatters-862	80	24	designed	design	VERB
brainmatters-862	80	25	cooperative	cooperative	ADJ
brainmatters-862	80	26	trials	trial	NOUN
brainmatters-862	80	27	(	(	PUNCT
brainmatters-862	80	28	grill	grill	NOUN
brainmatters-862	80	29	2003	2003	NUM
brainmatters-862	80	30	)	)	PUNCT
brainmatters-862	80	31	.	.	PUNCT
brainmatters-862	81	1	a	a	DET
brainmatters-862	81	2	mri	mri	NOUN
brainmatters-862	81	3	image	image	NOUN
brainmatters-862	81	4	of	of	ADP
brainmatters-862	81	5	an	an	DET
brainmatters-862	81	6	ependymoma	ependymoma	NOUN
brainmatters-862	81	7	tumor	tumor	NOUN
brainmatters-862	81	8	in	in	ADP
brainmatters-862	81	9	the	the	DET
brainmatters-862	81	10	spinal	spinal	ADJ
brainmatters-862	81	11	cord	cord	NOUN
brainmatters-862	81	12	(	(	PUNCT
brainmatters-862	81	13	n.c.i	n.c.i	NOUN
brainmatters-862	81	14	,	,	PUNCT
brainmatters-862	81	15	2021	2021	NUM
brainmatters-862	81	16	)	)	PUNCT
brainmatters-862	81	17	.	.	PUNCT
brainmatters-862	82	1	conclusion	conclusion	NOUN
brainmatters-862	82	2	ependymomas	ependymomas	PROPN
brainmatters-862	82	3	are	be	AUX
brainmatters-862	82	4	a	a	DET
brainmatters-862	82	5	very	very	ADV
brainmatters-862	82	6	aggressive	aggressive	ADJ
brainmatters-862	82	7	type	type	NOUN
brainmatters-862	82	8	of	of	ADP
brainmatters-862	82	9	brain	brain	NOUN
brainmatters-862	82	10	tumor	tumor	NOUN
brainmatters-862	82	11	that	that	PRON
brainmatters-862	82	12	occur	occur	VERB
brainmatters-862	82	13	in	in	ADP
brainmatters-862	82	14	both	both	CCONJ
brainmatters-862	82	15	pediatric	pediatric	ADJ
brainmatters-862	82	16	and	and	CCONJ
brainmatters-862	82	17	adult	adult	NOUN
brainmatters-862	82	18	patient	patient	NOUN
brainmatters-862	82	19	types	type	NOUN
brainmatters-862	82	20	.	.	PUNCT
brainmatters-862	83	1	brain	brain	NOUN
brainmatters-862	83	2	matters・volume	matters・volume	PROPN
brainmatters-862	83	3	v	v	PROPN
brainmatters-862	83	4	issue	issue	NOUN
brainmatters-862	83	5	ii	ii	NOUN
brainmatters-862	83	6	while	while	SCONJ
brainmatters-862	83	7	most	most	ADJ
brainmatters-862	83	8	cases	case	NOUN
brainmatters-862	83	9	of	of	ADP
brainmatters-862	83	10	this	this	DET
brainmatters-862	83	11	tumor	tumor	NOUN
brainmatters-862	83	12	type	type	NOUN
brainmatters-862	83	13	effect	effect	NOUN
brainmatters-862	83	14	pediatric	pediatric	ADJ
brainmatters-862	83	15	patients	patient	NOUN
brainmatters-862	83	16	in	in	ADP
brainmatters-862	83	17	the	the	DET
brainmatters-862	83	18	brain	brain	NOUN
brainmatters-862	83	19	with	with	ADP
brainmatters-862	83	20	very	very	ADV
brainmatters-862	83	21	little	little	ADJ
brainmatters-862	83	22	metastasis	metastasis	NOUN
brainmatters-862	83	23	from	from	ADP
brainmatters-862	83	24	other	other	ADJ
brainmatters-862	83	25	regions	region	NOUN
brainmatters-862	83	26	of	of	ADP
brainmatters-862	83	27	the	the	DET
brainmatters-862	83	28	body	body	NOUN
brainmatters-862	83	29	,	,	PUNCT
brainmatters-862	83	30	it	it	PRON
brainmatters-862	83	31	still	still	ADV
brainmatters-862	83	32	has	have	VERB
brainmatters-862	83	33	a	a	DET
brainmatters-862	83	34	worse	bad	ADJ
brainmatters-862	83	35	prognosis	prognosis	NOUN
brainmatters-862	83	36	compared	compare	VERB
brainmatters-862	83	37	to	to	ADP
brainmatters-862	83	38	adult	adult	NOUN
brainmatters-862	83	39	patients	patient	NOUN
brainmatters-862	83	40	.	.	PUNCT
brainmatters-862	84	1	the	the	DET
brainmatters-862	84	2	common	common	ADJ
brainmatters-862	84	3	treatment	treatment	NOUN
brainmatters-862	84	4	for	for	ADP
brainmatters-862	84	5	these	these	DET
brainmatters-862	84	6	tumors	tumor	NOUN
brainmatters-862	84	7	include	include	VERB
brainmatters-862	84	8	surgery	surgery	NOUN
brainmatters-862	84	9	as	as	ADV
brainmatters-862	84	10	well	well	ADV
brainmatters-862	84	11	as	as	ADP
brainmatters-862	84	12	chemotherapy	chemotherapy	NOUN
brainmatters-862	84	13	,	,	PUNCT
brainmatters-862	84	14	however	however	ADV
brainmatters-862	84	15	the	the	DET
brainmatters-862	84	16	tumor	tumor	NOUN
brainmatters-862	84	17	has	have	AUX
brainmatters-862	84	18	shown	show	VERB
brainmatters-862	84	19	to	to	PART
brainmatters-862	84	20	be	be	AUX
brainmatters-862	84	21	chemo	chemo	NOUN
brainmatters-862	84	22	resistant	resistant	ADJ
brainmatters-862	84	23	.	.	PUNCT
brainmatters-862	85	1	typically	typically	ADV
brainmatters-862	85	2	when	when	SCONJ
brainmatters-862	85	3	a	a	DET
brainmatters-862	85	4	tumor	tumor	NOUN
brainmatters-862	85	5	is	be	AUX
brainmatters-862	85	6	chemo	chemo	NOUN
brainmatters-862	85	7	resistant	resistant	ADJ
brainmatters-862	85	8	it	it	PRON
brainmatters-862	85	9	will	will	AUX
brainmatters-862	85	10	end	end	VERB
brainmatters-862	85	11	up	up	ADP
brainmatters-862	85	12	growing	grow	VERB
brainmatters-862	85	13	back	back	ADV
brainmatters-862	85	14	not	not	PART
brainmatters-862	85	15	too	too	ADV
brainmatters-862	85	16	long	long	ADV
brainmatters-862	85	17	after	after	ADP
brainmatters-862	85	18	the	the	DET
brainmatters-862	85	19	chemotherapy	chemotherapy	NOUN
brainmatters-862	85	20	and	and	CCONJ
brainmatters-862	85	21	continue	continue	VERB
brainmatters-862	85	22	to	to	PART
brainmatters-862	85	23	spread	spread	VERB
brainmatters-862	85	24	.	.	PUNCT
brainmatters-862	86	1	there	there	PRON
brainmatters-862	86	2	has	have	AUX
brainmatters-862	86	3	been	be	AUX
brainmatters-862	86	4	research	research	NOUN
brainmatters-862	86	5	conducted	conduct	VERB
brainmatters-862	86	6	that	that	SCONJ
brainmatters-862	86	7	shows	show	VERB
brainmatters-862	86	8	chemotherapy	chemotherapy	NOUN
brainmatters-862	86	9	may	may	AUX
brainmatters-862	86	10	not	not	PART
brainmatters-862	86	11	be	be	AUX
brainmatters-862	86	12	the	the	DET
brainmatters-862	86	13	best	good	ADJ
brainmatters-862	86	14	treatment	treatment	NOUN
brainmatters-862	86	15	due	due	ADP
brainmatters-862	86	16	to	to	ADP
brainmatters-862	86	17	its	its	PRON
brainmatters-862	86	18	lasting	last	VERB
brainmatters-862	86	19	complications	complication	NOUN
brainmatters-862	86	20	it	it	PRON
brainmatters-862	86	21	may	may	AUX
brainmatters-862	86	22	cause	cause	VERB
brainmatters-862	86	23	.	.	PUNCT
brainmatters-862	87	1	therefore	therefore	ADV
brainmatters-862	87	2	,	,	PUNCT
brainmatters-862	87	3	upon	upon	SCONJ
brainmatters-862	87	4	initial	initial	ADJ
brainmatters-862	87	5	surgery	surgery	NOUN
brainmatters-862	87	6	,	,	PUNCT
brainmatters-862	87	7	it	it	PRON
brainmatters-862	87	8	is	be	AUX
brainmatters-862	87	9	recommended	recommend	VERB
brainmatters-862	87	10	that	that	SCONJ
brainmatters-862	87	11	the	the	DET
brainmatters-862	87	12	surgeons	surgeon	NOUN
brainmatters-862	87	13	remove	remove	VERB
brainmatters-862	87	14	most	most	ADJ
brainmatters-862	87	15	of	of	ADP
brainmatters-862	87	16	the	the	DET
brainmatters-862	87	17	tumor	tumor	NOUN
brainmatters-862	87	18	in	in	ADP
brainmatters-862	87	19	order	order	NOUN
brainmatters-862	87	20	to	to	PART
brainmatters-862	87	21	try	try	VERB
brainmatters-862	87	22	and	and	CCONJ
brainmatters-862	87	23	eliminate	eliminate	VERB
brainmatters-862	87	24	as	as	ADV
brainmatters-862	87	25	much	much	ADJ
brainmatters-862	87	26	as	as	ADP
brainmatters-862	87	27	possible	possible	ADJ
brainmatters-862	87	28	.	.	PUNCT
brainmatters-862	88	1	more	more	ADJ
brainmatters-862	88	2	research	research	NOUN
brainmatters-862	88	3	needs	need	VERB
brainmatters-862	88	4	to	to	PART
brainmatters-862	88	5	be	be	AUX
brainmatters-862	88	6	done	do	VERB
brainmatters-862	88	7	to	to	PART
brainmatters-862	88	8	understand	understand	VERB
brainmatters-862	88	9	ependymomas	ependymomas	PROPN
brainmatters-862	88	10	on	on	ADP
brainmatters-862	88	11	a	a	DET
brainmatters-862	88	12	molecular	molecular	ADJ
brainmatters-862	88	13	level	level	NOUN
brainmatters-862	88	14	in	in	ADP
brainmatters-862	88	15	order	order	NOUN
brainmatters-862	88	16	to	to	PART
brainmatters-862	88	17	offer	offer	VERB
brainmatters-862	88	18	a	a	DET
brainmatters-862	88	19	more	more	ADV
brainmatters-862	88	20	effective	effective	ADJ
brainmatters-862	88	21	treatment	treatment	NOUN
brainmatters-862	88	22	for	for	ADP
brainmatters-862	88	23	pediatric	pediatric	ADJ
brainmatters-862	88	24	“	"	PUNCT
brainmatters-862	88	25	patients	patient	NOUN
brainmatters-862	88	26	”	"	PUNCT
brainmatters-862	88	27	.	.	PUNCT
brainmatters-862	89	1	references	reference	NOUN
brainmatters-862	89	2	1	1	NUM
brainmatters-862	89	3	.	.	PUNCT
brainmatters-862	89	4	butowski	butowski	PROPN
brainmatters-862	89	5	n.	n.	PROPN
brainmatters-862	89	6	a.	a.	PROPN
brainmatters-862	89	7	(	(	PUNCT
brainmatters-862	89	8	2015	2015	NUM
brainmatters-862	89	9	)	)	PUNCT
brainmatters-862	89	10	.	.	PUNCT
brainmatters-862	90	1	epidemiology	epidemiology	NOUN
brainmatters-862	90	2	and	and	CCONJ
brainmatters-862	90	3	diagnosis	diagnosis	NOUN
brainmatters-862	90	4	of	of	ADP
brainmatters-862	90	5	brain	brain	NOUN
brainmatters-862	90	6	tumors	tumor	NOUN
brainmatters-862	90	7	.	.	PUNCT
brainmatters-862	91	1	continuum	continuum	PROPN
brainmatters-862	91	2	(	(	PUNCT
brainmatters-862	91	3	minneapolis	minneapolis	PROPN
brainmatters-862	91	4	,	,	PUNCT
brainmatters-862	91	5	minn	minn	PROPN
brainmatters-862	91	6	.	.	PUNCT
brainmatters-862	91	7	)	)	PUNCT
brainmatters-862	91	8	,	,	PUNCT
brainmatters-862	91	9	21(2	21(2	NUM
brainmatters-862	91	10	neurooncology	neurooncology	NOUN
brainmatters-862	91	11	)	)	PUNCT
brainmatters-862	91	12	,	,	PUNCT
brainmatters-862	91	13	301–313	301–313	NUM
brainmatters-862	91	14	.	.	PUNCT
brainmatters-862	92	1	https://doi.org/10.1212/01.con.0000464171.50638.fa	https://doi.org/10.1212/01.con.0000464171.50638.fa	PROPN
brainmatters-862	92	2	2	2	X
brainmatters-862	92	3	.	.	X
brainmatters-862	92	4	collins	collins	PROPN
brainmatters-862	92	5	v.	v.	PROPN
brainmatters-862	92	6	p.	p.	PROPN
brainmatters-862	92	7	(	(	PUNCT
brainmatters-862	92	8	2004	2004	NUM
brainmatters-862	92	9	)	)	PUNCT
brainmatters-862	92	10	.	.	PUNCT
brainmatters-862	93	1	brain	brain	NOUN
brainmatters-862	93	2	tumours	tumours	NOUN
brainmatters-862	93	3	:	:	PUNCT
brainmatters-862	93	4	classification	classification	NOUN
brainmatters-862	93	5	and	and	CCONJ
brainmatters-862	93	6	genes	gene	NOUN
brainmatters-862	93	7	.	.	PUNCT
brainmatters-862	94	1	journal	journal	PROPN
brainmatters-862	94	2	of	of	ADP
brainmatters-862	94	3	neurology	neurology	NOUN
brainmatters-862	94	4	,	,	PUNCT
brainmatters-862	94	5	neurosurgery	neurosurgery	NOUN
brainmatters-862	94	6	,	,	PUNCT
brainmatters-862	94	7	and	and	CCONJ
brainmatters-862	94	8	psychiatry	psychiatry	NOUN
brainmatters-862	94	9	,	,	PUNCT
brainmatters-862	94	10	75	75	NUM
brainmatters-862	94	11	suppl	suppl	NOUN
brainmatters-862	94	12	2(suppl	2(suppl	PROPN
brainmatters-862	94	13	2	2	NUM
brainmatters-862	94	14	)	)	PUNCT
brainmatters-862	94	15	,	,	PUNCT
brainmatters-862	94	16	ii2	ii2	PROPN
brainmatters-862	94	17	–	–	PUNCT
brainmatters-862	94	18	ii11	ii11	PROPN
brainmatters-862	94	19	.	.	PUNCT
brainmatters-862	95	1	https://doi.org/10.1136/jnnp.2004.040337	https://doi.org/10.1136/jnnp.2004.040337	PROPN
brainmatters-862	95	2	3	3	NUM
brainmatters-862	95	3	.	.	PUNCT
brainmatters-862	95	4	cooper	cooper	PROPN
brainmatters-862	95	5	gm	gm	PROPN
brainmatters-862	95	6	.	.	PUNCT
brainmatters-862	96	1	the	the	DET
brainmatters-862	96	2	cell	cell	NOUN
brainmatters-862	96	3	:	:	PUNCT
brainmatters-862	96	4	a	a	DET
brainmatters-862	96	5	molecular	molecular	ADJ
brainmatters-862	96	6	approach	approach	NOUN
brainmatters-862	96	7	.	.	PUNCT
brainmatters-862	97	1	2nd	2nd	PROPN
brainmatters-862	97	2	edition	edition	PROPN
brainmatters-862	97	3	.	.	PUNCT
brainmatters-862	98	1	sunderland	sunderland	PROPN
brainmatters-862	98	2	(	(	PUNCT
brainmatters-862	98	3	ma	ma	PROPN
brainmatters-862	98	4	):	):	PUNCT
brainmatters-862	98	5	sinauer	sinauer	PROPN
brainmatters-862	98	6	associates	associate	NOUN
brainmatters-862	98	7	;	;	PUNCT
brainmatters-862	98	8	2000	2000	NUM
brainmatters-862	98	9	.	.	PUNCT
brainmatters-862	99	1	chapter	chapter	NOUN
brainmatters-862	99	2	15	15	NUM
brainmatters-862	99	3	,	,	PUNCT
brainmatters-862	99	4	cancer	cancer	NOUN
brainmatters-862	99	5	.	.	PUNCT
brainmatters-862	99	6	available	available	ADJ
brainmatters-862	99	7	from	from	ADP
brainmatters-862	99	8	:	:	PUNCT
brainmatters-862	99	9	https://www.ncbi.nlm.nih.gov/books/nbk9878	https://www.ncbi.nlm.nih.gov/books/nbk9878	ADJ
brainmatters-862	99	10	4	4	NUM
brainmatters-862	99	11	.	.	X
brainmatters-862	99	12	gerstner	gerstner	PROPN
brainmatters-862	99	13	,	,	PUNCT
brainmatters-862	99	14	e.	e.	PROPN
brainmatters-862	99	15	r.	r.	PROPN
brainmatters-862	99	16	,	,	PUNCT
brainmatters-862	99	17	&	&	CCONJ
brainmatters-862	99	18	pajtler	pajtler	PROPN
brainmatters-862	99	19	,	,	PUNCT
brainmatters-862	99	20	k.	k.	PROPN
brainmatters-862	99	21	w.	w.	PROPN
brainmatters-862	99	22	(	(	PUNCT
brainmatters-862	99	23	2018	2018	NUM
brainmatters-862	99	24	)	)	PUNCT
brainmatters-862	99	25	.	.	PUNCT
brainmatters-862	100	1	ependymoma	ependymoma	NOUN
brainmatters-862	100	2	.	.	PUNCT
brainmatters-862	101	1	seminars	seminar	NOUN
brainmatters-862	101	2	in	in	ADP
brainmatters-862	101	3	neurology	neurology	NOUN
brainmatters-862	101	4	,	,	PUNCT
brainmatters-862	101	5	38(1	38(1	NUM
brainmatters-862	101	6	)	)	PUNCT
brainmatters-862	101	7	,	,	PUNCT
brainmatters-862	101	8	104–111	104–111	NUM
brainmatters-862	101	9	.	.	PUNCT
brainmatters-862	102	1	https://doi.org/10.1055/s-0038-1636503	https://doi.org/10.1055/s-0038-1636503	PROPN
brainmatters-862	102	2	5	5	NUM
brainmatters-862	102	3	.	.	PUNCT
brainmatters-862	102	4	grill	grill	NOUN
brainmatters-862	102	5	,	,	PUNCT
brainmatters-862	102	6	j.	j.	PROPN
brainmatters-862	102	7	,	,	PUNCT
brainmatters-862	102	8	pascal	pascal	PROPN
brainmatters-862	102	9	,	,	PUNCT
brainmatters-862	102	10	c.	c.	PROPN
brainmatters-862	102	11	,	,	PUNCT
brainmatters-862	102	12	&	&	CCONJ
brainmatters-862	102	13	chantal	chantal	PROPN
brainmatters-862	102	14	,	,	PUNCT
brainmatters-862	102	15	k.	k.	PROPN
brainmatters-862	102	16	(	(	PUNCT
brainmatters-862	102	17	2003	2003	NUM
brainmatters-862	102	18	)	)	PUNCT
brainmatters-862	102	19	.	.	PUNCT
brainmatters-862	103	1	childhood	childhood	NOUN
brainmatters-862	103	2	ependymoma	ependymoma	PROPN
brainmatters-862	103	3	:	:	PUNCT
brainmatters-862	103	4	a	a	DET
brainmatters-862	103	5	systematic	systematic	ADJ
brainmatters-862	103	6	review	review	NOUN
brainmatters-862	103	7	of	of	ADP
brainmatters-862	103	8	treatment	treatment	NOUN
brainmatters-862	103	9	options	option	NOUN
brainmatters-862	103	10	and	and	CCONJ
brainmatters-862	103	11	strategies	strategy	NOUN
brainmatters-862	103	12	.	.	PUNCT
brainmatters-862	104	1	paediatric	paediatric	ADJ
brainmatters-862	104	2	drugs	drug	NOUN
brainmatters-862	104	3	,	,	PUNCT
brainmatters-862	104	4	5(8	5(8	NUM
brainmatters-862	104	5	)	)	PUNCT
brainmatters-862	104	6	,	,	PUNCT
brainmatters-862	104	7	533–543	533–543	NUM
brainmatters-862	104	8	.	.	PUNCT
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brainmatters-862	105	3	.	.	PUNCT
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brainmatters-862	105	7	,	,	PUNCT
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brainmatters-862	105	9	,	,	PUNCT
brainmatters-862	105	10	t.	t.	PROPN
brainmatters-862	105	11	s.	s.	PROPN
brainmatters-862	105	12	,	,	PUNCT
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brainmatters-862	105	20	)	)	PUNCT
brainmatters-862	105	21	.	.	PUNCT
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brainmatters-862	106	2	and	and	CCONJ
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brainmatters-862	106	5	ependymomas	ependymomas	PROPN
brainmatters-862	106	6	.	.	PUNCT
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brainmatters-862	107	3	oncology	oncology	NOUN
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brainmatters-862	107	6	)	)	PUNCT
brainmatters-862	107	7	,	,	PUNCT
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brainmatters-862	107	9	.	.	PUNCT
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brainmatters-862	108	2	7	7	NUM
brainmatters-862	108	3	.	.	PUNCT
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brainmatters-862	108	10	.	.	PUNCT
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brainmatters-862	109	2	updated	update	VERB
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brainmatters-862	109	4	jun	jun	PROPN
brainmatters-862	109	5	30	30	NUM
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brainmatters-862	109	7	.	.	PUNCT
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brainmatters-862	111	3	]	]	PUNCT
brainmatters-862	111	4	.	.	PUNCT
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brainmatters-862	112	2	island	island	NOUN
brainmatters-862	112	3	(	(	PUNCT
brainmatters-862	112	4	fl	fl	PROPN
brainmatters-862	112	5	):	):	PUNCT
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brainmatters-862	112	8	;	;	PUNCT
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brainmatters-862	112	11	.	.	PUNCT
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brainmatters-862	113	6	.	.	PUNCT
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brainmatters-862	114	2	pediatric	pediatric	ADJ
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brainmatters-862	114	5	.	.	PUNCT
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brainmatters-862	117	21	-	-	PUNCT
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brainmatters-862	117	27	=	=	ADJ
brainmatters-862	117	28	images&cd	images&cd	NOUN
brainmatters-862	117	29	=	=	NOUN
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brainmatters-862	118	3	)	)	PUNCT
brainmatters-862	118	4	.	.	PUNCT
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brainmatters-862	119	4	treatment	treatment	NOUN
brainmatters-862	119	5	[	[	X
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brainmatters-862	119	7	]	]	PUNCT
brainmatters-862	119	8	.	.	PUNCT
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brainmatters-862	120	4	.	.	PUNCT
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brainmatters-862	121	4	=	=	SYM
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