id	sid	tid	token	lemma	pos
bjos-8661512	1	1	1http://dx.doi.org/10.20396/bjos.v20i00.8661512	1http://dx.doi.org/10.20396/bjos.v20i00.8661512	ADJ
bjos-8661512	1	2	volume	volume	NOUN
bjos-8661512	1	3	20	20	NUM
bjos-8661512	1	4	2021	2021	NUM
bjos-8661512	1	5	e211512	e211512	PROPN
bjos-8661512	1	6	original	original	ADJ
bjos-8661512	1	7	article	article	NOUN
bjos-8661512	1	8	1	1	NUM
bjos-8661512	1	9	postgraduate	postgraduate	NOUN
bjos-8661512	1	10	program	program	NOUN
bjos-8661512	1	11	in	in	ADP
bjos-8661512	1	12	health	health	NOUN
bjos-8661512	1	13	sciences	sciences	PROPN
bjos-8661512	1	14	,	,	PUNCT
bjos-8661512	1	15	university	university	NOUN
bjos-8661512	1	16	of	of	ADP
bjos-8661512	1	17	brasília	brasília	PROPN
bjos-8661512	1	18	,	,	PUNCT
bjos-8661512	1	19	brasília	brasília	PROPN
bjos-8661512	1	20	,	,	PUNCT
bjos-8661512	1	21	distrito	distrito	PROPN
bjos-8661512	1	22	federal	federal	PROPN
bjos-8661512	1	23	,	,	PUNCT
bjos-8661512	1	24	brazil	brazil	PROPN
bjos-8661512	1	25	.	.	PUNCT
bjos-8661512	2	1	2	2	NUM
bjos-8661512	2	2	proteomic	proteomic	ADJ
bjos-8661512	2	3	and	and	CCONJ
bjos-8661512	2	4	biochemical	biochemical	ADJ
bjos-8661512	2	5	analysis	analysis	NOUN
bjos-8661512	2	6	center	center	NOUN
bjos-8661512	2	7	,	,	PUNCT
bjos-8661512	2	8	postgraduate	postgraduate	NOUN
bjos-8661512	2	9	program	program	NOUN
bjos-8661512	2	10	in	in	ADP
bjos-8661512	2	11	genomic	genomic	ADJ
bjos-8661512	2	12	sciences	science	NOUN
bjos-8661512	2	13	and	and	CCONJ
bjos-8661512	2	14	biotechnology	biotechnology	NOUN
bjos-8661512	2	15	,	,	PUNCT
bjos-8661512	2	16	catholic	catholic	PROPN
bjos-8661512	2	17	university	university	PROPN
bjos-8661512	2	18	of	of	ADP
bjos-8661512	2	19	brasilia	brasilia	PROPN
bjos-8661512	2	20	,	,	PUNCT
bjos-8661512	2	21	brasília	brasília	PROPN
bjos-8661512	2	22	,	,	PUNCT
bjos-8661512	2	23	distrito	distrito	PROPN
bjos-8661512	2	24	federal	federal	PROPN
bjos-8661512	2	25	,	,	PUNCT
bjos-8661512	2	26	brazil	brazil	PROPN
bjos-8661512	2	27	.	.	PUNCT
bjos-8661512	3	1	3	3	NUM
bjos-8661512	3	2	dentistry	dentistry	NOUN
bjos-8661512	3	3	course	course	NOUN
bjos-8661512	3	4	,	,	PUNCT
bjos-8661512	3	5	catholic	catholic	PROPN
bjos-8661512	3	6	university	university	PROPN
bjos-8661512	3	7	of	of	ADP
bjos-8661512	3	8	brasília	brasília	PROPN
bjos-8661512	3	9	,	,	PUNCT
bjos-8661512	3	10	brasília	brasília	PROPN
bjos-8661512	3	11	,	,	PUNCT
bjos-8661512	3	12	federal	federal	ADJ
bjos-8661512	3	13	district	district	NOUN
bjos-8661512	3	14	,	,	PUNCT
bjos-8661512	3	15	brazil	brazil	PROPN
bjos-8661512	3	16	.	.	PUNCT
bjos-8661512	4	1	4	4	NUM
bjos-8661512	4	2	postgraduate	postgraduate	NOUN
bjos-8661512	4	3	program	program	NOUN
bjos-8661512	4	4	in	in	ADP
bjos-8661512	4	5	biotechnology	biotechnology	NOUN
bjos-8661512	4	6	and	and	CCONJ
bjos-8661512	4	7	biodivesity	biodivesity	NOUN
bjos-8661512	4	8	,	,	PUNCT
bjos-8661512	4	9	brasilia	brasilia	PROPN
bjos-8661512	4	10	university	university	PROPN
bjos-8661512	4	11	,	,	PUNCT
bjos-8661512	4	12	brasilia	brasilia	PROPN
bjos-8661512	4	13	,	,	PUNCT
bjos-8661512	4	14	distrito	distrito	PROPN
bjos-8661512	4	15	federal	federal	PROPN
bjos-8661512	4	16	,	,	PUNCT
bjos-8661512	4	17	brazil	brazil	PROPN
bjos-8661512	4	18	.	.	PUNCT
bjos-8661512	5	1	5	5	NUM
bjos-8661512	5	2	graduate	graduate	NOUN
bjos-8661512	5	3	program	program	NOUN
bjos-8661512	5	4	in	in	ADP
bjos-8661512	5	5	health	health	NOUN
bjos-8661512	5	6	and	and	CCONJ
bjos-8661512	5	7	development	development	NOUN
bjos-8661512	5	8	in	in	ADP
bjos-8661512	5	9	the	the	DET
bjos-8661512	5	10	midwest	midwest	PROPN
bjos-8661512	5	11	region	region	NOUN
bjos-8661512	5	12	.	.	PUNCT
bjos-8661512	6	1	faculty	faculty	NOUN
bjos-8661512	6	2	of	of	ADP
bjos-8661512	6	3	medicine	medicine	NOUN
bjos-8661512	6	4	.	.	PUNCT
bjos-8661512	7	1	federal	federal	ADJ
bjos-8661512	7	2	university	university	PROPN
bjos-8661512	7	3	of	of	ADP
bjos-8661512	7	4	mato	mato	PROPN
bjos-8661512	7	5	grosso	grosso	PROPN
bjos-8661512	7	6	do	do	AUX
bjos-8661512	7	7	sul	sul	PROPN
bjos-8661512	7	8	.	.	PROPN
bjos-8661512	7	9	campo	campo	PROPN
bjos-8661512	7	10	grande	grande	PROPN
bjos-8661512	7	11	.	.	PUNCT
bjos-8661512	7	12	brazil	brazil	PROPN
bjos-8661512	7	13	.	.	PUNCT
bjos-8661512	8	1	6	6	NUM
bjos-8661512	8	2	s	s	X
bjos-8661512	8	3	-	-	PUNCT
bjos-8661512	8	4	inova	inova	VERB
bjos-8661512	8	5	biotech	biotech	NOUN
bjos-8661512	8	6	,	,	PUNCT
bjos-8661512	8	7	graduate	graduate	NOUN
bjos-8661512	8	8	program	program	NOUN
bjos-8661512	8	9	in	in	ADP
bjos-8661512	8	10	biotechnology	biotechnology	NOUN
bjos-8661512	8	11	,	,	PUNCT
bjos-8661512	8	12	dom	dom	PROPN
bjos-8661512	8	13	bosco	bosco	PROPN
bjos-8661512	8	14	catholic	catholic	PROPN
bjos-8661512	8	15	university	university	PROPN
bjos-8661512	8	16	,	,	PUNCT
bjos-8661512	8	17	campo	campo	PROPN
bjos-8661512	8	18	grande	grande	PROPN
bjos-8661512	8	19	,	,	PUNCT
bjos-8661512	8	20	mato	mato	PROPN
bjos-8661512	8	21	grosso	grosso	PROPN
bjos-8661512	8	22	do	do	AUX
bjos-8661512	8	23	sul	sul	PROPN
bjos-8661512	8	24	,	,	PUNCT
bjos-8661512	8	25	brazil	brazil	PROPN
bjos-8661512	8	26	.	.	PUNCT
bjos-8661512	9	1	corresponding	correspond	VERB
bjos-8661512	9	2	author	author	NOUN
bjos-8661512	9	3	:	:	PUNCT
bjos-8661512	9	4	name	name	NOUN
bjos-8661512	9	5	:	:	PUNCT
bjos-8661512	9	6	taia	taia	PROPN
bjos-8661512	9	7	maria	maria	PROPN
bjos-8661512	9	8	berto	berto	PROPN
bjos-8661512	9	9	rezende	rezende	PROPN
bjos-8661512	9	10	full	full	ADJ
bjos-8661512	9	11	postal	postal	ADJ
bjos-8661512	9	12	address	address	NOUN
bjos-8661512	9	13	:	:	PUNCT
bjos-8661512	9	14	universidade	universidade	PROPN
bjos-8661512	9	15	católica	católica	PROPN
bjos-8661512	9	16	de	de	PROPN
bjos-8661512	9	17	brasília	brasília	PROPN
bjos-8661512	9	18	pós	pós	PROPN
bjos-8661512	9	19	-	-	PUNCT
bjos-8661512	9	20	graduação	graduação	NOUN
bjos-8661512	9	21	em	em	PRON
bjos-8661512	9	22	ciências	ciências	VERB
bjos-8661512	9	23	genômicas	genômicas	PROPN
bjos-8661512	9	24	e	e	PART
bjos-8661512	9	25	biotecnologia	biotecnologia	NOUN
bjos-8661512	9	26	sgan	sgan	NOUN
bjos-8661512	9	27	916n	916n	PROPN
bjos-8661512	9	28	–	–	PUNCT
bjos-8661512	9	29	av	av	NOUN
bjos-8661512	9	30	.	.	PUNCT
bjos-8661512	9	31	w5	w5	PROPN
bjos-8661512	9	32	–	–	PUNCT
bjos-8661512	9	33	campus	campus	PROPN
bjos-8661512	9	34	ii	ii	PROPN
bjos-8661512	9	35	–	–	PUNCT
bjos-8661512	9	36	módulo	módulo	PROPN
bjos-8661512	9	37	c	c	NOUN
bjos-8661512	9	38	,	,	PUNCT
bjos-8661512	9	39	room	room	NOUN
bjos-8661512	9	40	c-221	c-221	PROPN
bjos-8661512	9	41	brasília	brasília	PROPN
bjos-8661512	9	42	-	-	PUNCT
bjos-8661512	9	43	df	df	PROPN
bjos-8661512	9	44	,	,	PUNCT
bjos-8661512	9	45	brazil	brazil	PROPN
bjos-8661512	9	46	fone	fone	NOUN
bjos-8661512	9	47	:	:	PUNCT
bjos-8661512	9	48	+	+	CCONJ
bjos-8661512	9	49	55	55	NUM
bjos-8661512	9	50	-	-	SYM
bjos-8661512	9	51	61	61	NUM
bjos-8661512	9	52	-	-	PUNCT
bjos-8661512	9	53	98134	98134	NUM
bjos-8661512	9	54	-	-	PUNCT
bjos-8661512	9	55	9001	9001	NUM
bjos-8661512	9	56	fax	fax	NOUN
bjos-8661512	9	57	:	:	PUNCT
bjos-8661512	9	58	+	+	NUM
bjos-8661512	9	59	55	55	NUM
bjos-8661512	9	60	-	-	SYM
bjos-8661512	9	61	61	61	NUM
bjos-8661512	9	62	-	-	PUNCT
bjos-8661512	9	63	3347	3347	NUM
bjos-8661512	9	64	-	-	SYM
bjos-8661512	9	65	4797	4797	NUM
bjos-8661512	9	66	e	e	NOUN
bjos-8661512	9	67	-	-	NOUN
bjos-8661512	9	68	mail	mail	NOUN
bjos-8661512	9	69	:	:	PUNCT
bjos-8661512	9	70	taiambr@gmail.com	taiambr@gmail.com	X
bjos-8661512	10	1	secondary	secondary	ADJ
bjos-8661512	10	2	e	e	NOUN
bjos-8661512	10	3	-	-	NOUN
bjos-8661512	10	4	mail	mail	NOUN
bjos-8661512	10	5	:	:	PUNCT
bjos-8661512	10	6	taia@ucb.br	taia@ucb.br	NUM
bjos-8661512	10	7	received	receive	VERB
bjos-8661512	10	8	:	:	PUNCT
bjos-8661512	10	9	october	october	PROPN
bjos-8661512	10	10	06	06	NUM
bjos-8661512	10	11	,	,	PUNCT
bjos-8661512	10	12	2020	2020	NUM
bjos-8661512	10	13	accepted	accept	VERB
bjos-8661512	10	14	:	:	PUNCT
bjos-8661512	10	15	january	january	PROPN
bjos-8661512	10	16	21	21	NUM
bjos-8661512	10	17	,	,	PUNCT
bjos-8661512	10	18	2021	2021	NUM
bjos-8661512	10	19	host	host	NOUN
bjos-8661512	10	20	defense	defense	NOUN
bjos-8661512	10	21	peptides	peptide	NOUN
bjos-8661512	10	22	clavanins	clavanin	VERB
bjos-8661512	10	23	a	a	PRON
bjos-8661512	10	24	and	and	CCONJ
bjos-8661512	10	25	mo	mo	PROPN
bjos-8661512	10	26	reduce	reduce	VERB
bjos-8661512	10	27	in	in	ADP
bjos-8661512	10	28	vitro	vitro	X
bjos-8661512	10	29	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	10	30	ingrid	ingrid	NOUN
bjos-8661512	10	31	aquino	aquino	PROPN
bjos-8661512	10	32	amorim1,2	amorim1,2	PROPN
bjos-8661512	10	33	,	,	PUNCT
bjos-8661512	10	34	stella	stella	PROPN
bjos-8661512	10	35	maris	maris	PROPN
bjos-8661512	10	36	de	de	PROPN
bjos-8661512	10	37	freitas	freitas	PROPN
bjos-8661512	10	38	lima2,3	lima2,3	PROPN
bjos-8661512	10	39	,	,	PUNCT
bjos-8661512	10	40	ana	ana	PROPN
bjos-8661512	10	41	paula	paula	PROPN
bjos-8661512	10	42	de	de	PROPN
bjos-8661512	10	43	castro	castro	PROPN
bjos-8661512	10	44	cantuária1,2	cantuária1,2	PROPN
bjos-8661512	10	45	,	,	PUNCT
bjos-8661512	10	46	mirna	mirna	PROPN
bjos-8661512	10	47	de	de	PROPN
bjos-8661512	10	48	souza	souza	PROPN
bjos-8661512	10	49	freire2,4	freire2,4	PROPN
bjos-8661512	10	50	,	,	PUNCT
bjos-8661512	10	51	jeeser	jeeser	NOUN
bjos-8661512	10	52	alves	alves	PROPN
bjos-8661512	10	53	de	de	PROPN
bjos-8661512	10	54	almeida5	almeida5	PROPN
bjos-8661512	10	55	,	,	PUNCT
bjos-8661512	10	56	octávio	octávio	NOUN
bjos-8661512	10	57	luiz	luiz	PROPN
bjos-8661512	10	58	franco2,6	franco2,6	PROPN
bjos-8661512	10	59	,	,	PUNCT
bjos-8661512	10	60	taia	taia	PROPN
bjos-8661512	10	61	maria	maria	PROPN
bjos-8661512	10	62	berto	berto	PROPN
bjos-8661512	10	63	rezende1,2,3	rezende1,2,3	PROPN
bjos-8661512	10	64	,	,	PUNCT
bjos-8661512	10	65	*	*	PUNCT
bjos-8661512	10	66	aim	aim	NOUN
bjos-8661512	10	67	:	:	PUNCT
bjos-8661512	10	68	several	several	ADJ
bjos-8661512	10	69	systemic	systemic	ADJ
bjos-8661512	10	70	diseases	disease	NOUN
bjos-8661512	10	71	,	,	PUNCT
bjos-8661512	10	72	such	such	ADJ
bjos-8661512	10	73	as	as	ADP
bjos-8661512	10	74	periodontitis	periodontitis	NOUN
bjos-8661512	10	75	and	and	CCONJ
bjos-8661512	10	76	apical	apical	ADJ
bjos-8661512	10	77	periodontitis	periodontitis	NOUN
bjos-8661512	10	78	,	,	PUNCT
bjos-8661512	10	79	can	can	AUX
bjos-8661512	10	80	cause	cause	VERB
bjos-8661512	10	81	extensive	extensive	ADJ
bjos-8661512	10	82	bone	bone	NOUN
bjos-8661512	10	83	resorption	resorption	NOUN
bjos-8661512	10	84	.	.	PUNCT
bjos-8661512	11	1	host	host	NOUN
bjos-8661512	11	2	defense	defense	NOUN
bjos-8661512	11	3	peptides	peptide	NOUN
bjos-8661512	11	4	may	may	AUX
bjos-8661512	11	5	have	have	VERB
bjos-8661512	11	6	the	the	DET
bjos-8661512	11	7	potential	potential	NOUN
bjos-8661512	11	8	for	for	ADP
bjos-8661512	11	9	the	the	DET
bjos-8661512	11	10	development	development	NOUN
bjos-8661512	11	11	of	of	ADP
bjos-8661512	11	12	novel	novel	ADJ
bjos-8661512	11	13	therapies	therapy	NOUN
bjos-8661512	11	14	for	for	ADP
bjos-8661512	11	15	the	the	DET
bjos-8661512	11	16	bone	bone	NOUN
bjos-8661512	11	17	resorption	resorption	NOUN
bjos-8661512	11	18	process	process	NOUN
bjos-8661512	11	19	.	.	PUNCT
bjos-8661512	12	1	this	this	DET
bjos-8661512	12	2	study	study	NOUN
bjos-8661512	12	3	evaluated	evaluate	VERB
bjos-8661512	12	4	the	the	DET
bjos-8661512	12	5	potential	potential	NOUN
bjos-8661512	12	6	of	of	ADP
bjos-8661512	12	7	host	host	NOUN
bjos-8661512	12	8	defense	defense	NOUN
bjos-8661512	12	9	peptides	peptide	NOUN
bjos-8661512	12	10	clavanins	clavanin	VERB
bjos-8661512	12	11	a	a	PRON
bjos-8661512	12	12	,	,	PUNCT
bjos-8661512	12	13	mo	mo	NOUN
bjos-8661512	12	14	,	,	PUNCT
bjos-8661512	12	15	and	and	CCONJ
bjos-8661512	12	16	ll-37	ll-37	NOUN
bjos-8661512	12	17	in	in	ADV
bjos-8661512	12	18	in	in	ADP
bjos-8661512	12	19	vitro	vitro	X
bjos-8661512	12	20	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	12	21	.	.	PUNCT
bjos-8661512	13	1	methods	method	NOUN
bjos-8661512	13	2	:	:	PUNCT
bjos-8661512	13	3	raw	raw	ADJ
bjos-8661512	13	4	264.7	264.7	NUM
bjos-8661512	13	5	cultures	culture	NOUN
bjos-8661512	13	6	were	be	AUX
bjos-8661512	13	7	stimulated	stimulate	VERB
bjos-8661512	13	8	with	with	ADP
bjos-8661512	13	9	recombinant	recombinant	NOUN
bjos-8661512	13	10	of	of	ADP
bjos-8661512	13	11	receptor	receptor	NOUN
bjos-8661512	13	12	activator	activator	NOUN
bjos-8661512	13	13	of	of	ADP
bjos-8661512	13	14	nuclear	nuclear	ADJ
bjos-8661512	13	15	factor	factor	NOUN
bjos-8661512	13	16	kappa	kappa	PROPN
bjos-8661512	13	17	b	b	PROPN
bjos-8661512	13	18	ligand	ligand	PROPN
bjos-8661512	13	19	in	in	ADP
bjos-8661512	13	20	the	the	DET
bjos-8661512	13	21	presence	presence	NOUN
bjos-8661512	13	22	of	of	ADP
bjos-8661512	13	23	different	different	ADJ
bjos-8661512	13	24	tested	test	VERB
bjos-8661512	13	25	concentrations	concentration	NOUN
bjos-8661512	13	26	of	of	ADP
bjos-8661512	13	27	host	host	NOUN
bjos-8661512	13	28	defense	defense	NOUN
bjos-8661512	13	29	peptides	peptide	NOUN
bjos-8661512	13	30	,	,	PUNCT
bjos-8661512	13	31	besides	besides	SCONJ
bjos-8661512	13	32	calcium	calcium	NOUN
bjos-8661512	13	33	hydroxide	hydroxide	NOUN
bjos-8661512	13	34	and	and	CCONJ
bjos-8661512	13	35	doxycycline	doxycycline	NOUN
bjos-8661512	13	36	.	.	PUNCT
bjos-8661512	14	1	cellular	cellular	ADJ
bjos-8661512	14	2	viability	viability	NOUN
bjos-8661512	14	3	,	,	PUNCT
bjos-8661512	14	4	nitric	nitric	ADJ
bjos-8661512	14	5	oxide	oxide	NOUN
bjos-8661512	14	6	production	production	NOUN
bjos-8661512	14	7	,	,	PUNCT
bjos-8661512	14	8	and	and	CCONJ
bjos-8661512	14	9	a	a	DET
bjos-8661512	14	10	number	number	NOUN
bjos-8661512	14	11	of	of	ADP
bjos-8661512	14	12	differentiated	differentiated	ADJ
bjos-8661512	14	13	osteoclast	osteoclast	ADJ
bjos-8661512	14	14	-	-	PUNCT
bjos-8661512	14	15	like	like	ADJ
bjos-8661512	14	16	cells	cell	NOUN
bjos-8661512	14	17	were	be	AUX
bjos-8661512	14	18	also	also	ADV
bjos-8661512	14	19	evaluated	evaluate	VERB
bjos-8661512	14	20	.	.	PUNCT
bjos-8661512	15	1	results	result	NOUN
bjos-8661512	15	2	:	:	PUNCT
bjos-8661512	15	3	results	result	NOUN
bjos-8661512	15	4	showed	show	VERB
bjos-8661512	15	5	that	that	SCONJ
bjos-8661512	15	6	none	none	NOUN
bjos-8661512	15	7	of	of	ADP
bjos-8661512	15	8	the	the	DET
bjos-8661512	15	9	substances	substance	NOUN
bjos-8661512	15	10	were	be	AUX
bjos-8661512	15	11	cytotoxic	cytotoxic	ADJ
bjos-8661512	15	12	,	,	PUNCT
bjos-8661512	15	13	except	except	SCONJ
bjos-8661512	15	14	for	for	ADP
bjos-8661512	15	15	128	128	NUM
bjos-8661512	15	16	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	15	17	of	of	ADP
bjos-8661512	15	18	doxycycline	doxycycline	NOUN
bjos-8661512	15	19	after	after	ADP
bjos-8661512	15	20	3	3	NUM
bjos-8661512	15	21	days	day	NOUN
bjos-8661512	15	22	.	.	PUNCT
bjos-8661512	16	1	host	host	NOUN
bjos-8661512	16	2	defense	defense	NOUN
bjos-8661512	16	3	peptides	peptide	NOUN
bjos-8661512	16	4	,	,	PUNCT
bjos-8661512	16	5	calcium	calcium	NOUN
bjos-8661512	16	6	hydroxide	hydroxide	NOUN
bjos-8661512	16	7	,	,	PUNCT
bjos-8661512	16	8	and	and	CCONJ
bjos-8661512	16	9	doxycycline	doxycycline	NOUN
bjos-8661512	16	10	did	do	AUX
bjos-8661512	16	11	not	not	PART
bjos-8661512	16	12	interfere	interfere	VERB
bjos-8661512	16	13	in	in	ADP
bjos-8661512	16	14	nitric	nitric	ADJ
bjos-8661512	16	15	oxide	oxide	NOUN
bjos-8661512	16	16	production	production	NOUN
bjos-8661512	16	17	or	or	CCONJ
bjos-8661512	16	18	downregulated	downregulate	VERB
bjos-8661512	16	19	it	it	PRON
bjos-8661512	16	20	.	.	PUNCT
bjos-8661512	17	1	an	an	DET
bjos-8661512	17	2	exception	exception	NOUN
bjos-8661512	17	3	was	be	AUX
bjos-8661512	17	4	observed	observe	VERB
bjos-8661512	17	5	in	in	ADP
bjos-8661512	17	6	the	the	DET
bjos-8661512	17	7	presence	presence	NOUN
bjos-8661512	17	8	of	of	ADP
bjos-8661512	17	9	2	2	NUM
bjos-8661512	17	10	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	17	11	of	of	ADP
bjos-8661512	17	12	doxycycline	doxycycline	NOUN
bjos-8661512	17	13	,	,	PUNCT
bjos-8661512	17	14	in	in	ADP
bjos-8661512	17	15	which	which	PRON
bjos-8661512	17	16	nitric	nitric	ADJ
bjos-8661512	17	17	oxide	oxide	NOUN
bjos-8661512	17	18	production	production	NOUN
bjos-8661512	17	19	was	be	AUX
bjos-8661512	17	20	up	up	ADV
bjos-8661512	17	21	-	-	PUNCT
bjos-8661512	17	22	regulated	regulated	ADJ
bjos-8661512	17	23	.	.	PUNCT
bjos-8661512	18	1	all	all	DET
bjos-8661512	18	2	host	host	NOUN
bjos-8661512	18	3	defense	defense	NOUN
bjos-8661512	18	4	peptides	peptide	NOUN
bjos-8661512	18	5	were	be	AUX
bjos-8661512	18	6	capable	capable	ADJ
bjos-8661512	18	7	of	of	ADP
bjos-8661512	18	8	reducing	reduce	VERB
bjos-8661512	18	9	osteoclast	osteoclast	ADJ
bjos-8661512	18	10	-	-	PUNCT
bjos-8661512	18	11	like	like	ADJ
bjos-8661512	18	12	cell	cell	NOUN
bjos-8661512	18	13	differentiation	differentiation	NOUN
bjos-8661512	18	14	.	.	PUNCT
bjos-8661512	19	1	conclusion	conclusion	NOUN
bjos-8661512	19	2	:	:	PUNCT
bjos-8661512	19	3	host	host	NOUN
bjos-8661512	19	4	defense	defense	NOUN
bjos-8661512	19	5	peptides	peptide	NOUN
bjos-8661512	19	6	clavanins	clavanin	VERB
bjos-8661512	19	7	a	a	PRON
bjos-8661512	19	8	and	and	CCONJ
bjos-8661512	19	9	mo	mo	PROPN
bjos-8661512	19	10	demonstrated	demonstrate	VERB
bjos-8661512	19	11	to	to	PART
bjos-8661512	19	12	be	be	AUX
bjos-8661512	19	13	potential	potential	ADJ
bjos-8661512	19	14	suppressors	suppressor	NOUN
bjos-8661512	19	15	of	of	ADP
bjos-8661512	19	16	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	19	17	in	in	ADP
bjos-8661512	19	18	vitro	vitro	ADJ
bjos-8661512	19	19	without	without	ADP
bjos-8661512	19	20	interfering	interfere	VERB
bjos-8661512	19	21	in	in	ADP
bjos-8661512	19	22	cellular	cellular	ADJ
bjos-8661512	19	23	viability	viability	NOUN
bjos-8661512	19	24	and	and	CCONJ
bjos-8661512	19	25	nitric	nitric	ADJ
bjos-8661512	19	26	oxide	oxide	NOUN
bjos-8661512	19	27	production	production	NOUN
bjos-8661512	19	28	.	.	PUNCT
bjos-8661512	20	1	these	these	DET
bjos-8661512	20	2	promising	promising	ADJ
bjos-8661512	20	3	results	result	NOUN
bjos-8661512	20	4	need	need	VERB
bjos-8661512	20	5	to	to	PART
bjos-8661512	20	6	be	be	AUX
bjos-8661512	20	7	further	far	ADV
bjos-8661512	20	8	analyzed	analyze	VERB
bjos-8661512	20	9	in	in	ADP
bjos-8661512	20	10	in	in	ADP
bjos-8661512	20	11	vivo	vivo	NOUN
bjos-8661512	20	12	models	model	NOUN
bjos-8661512	20	13	of	of	ADP
bjos-8661512	20	14	bone	bone	NOUN
bjos-8661512	20	15	resorption	resorption	NOUN
bjos-8661512	20	16	.	.	PUNCT
bjos-8661512	21	1	keywords	keyword	NOUN
bjos-8661512	21	2	:	:	PUNCT
bjos-8661512	21	3	bone	bone	NOUN
bjos-8661512	21	4	resorption	resorption	NOUN
bjos-8661512	21	5	.	.	PUNCT
bjos-8661512	22	1	antimicrobial	antimicrobial	ADJ
bjos-8661512	22	2	cationic	cationic	ADJ
bjos-8661512	22	3	peptides	peptide	NOUN
bjos-8661512	22	4	.	.	PUNCT
bjos-8661512	22	5	nitric	nitric	ADJ
bjos-8661512	22	6	oxide	oxide	NOUN
bjos-8661512	22	7	.	.	PUNCT
bjos-8661512	23	1	osteogenesis	osteogenesis	NOUN
bjos-8661512	23	2	.	.	PUNCT
bjos-8661512	24	1	mailto:taia@ucb.br	mailto:taia@ucb.br	NOUN
bjos-8661512	25	1	https://orcid.org/0000-0002-1340-7091	https://orcid.org/0000-0002-1340-7091	NOUN
bjos-8661512	25	2	https://orcid.org/0000-0003-1359-8761	https://orcid.org/0000-0003-1359-8761	PROPN
bjos-8661512	25	3	https://orcid.org/0000-0001-5828-450x	https://orcid.org/0000-0001-5828-450x	INTJ
bjos-8661512	25	4	https://orcid.org/0000-0002-3409-8005	https://orcid.org/0000-0002-3409-8005	INTJ
bjos-8661512	25	5	https://orcid.org/0000-0001-9546-0525	https://orcid.org/0000-0001-9546-0525	PROPN
bjos-8661512	25	6	http://orcid.org/0000-0002-4148-0659	http://orcid.org/0000-0002-4148-0659	PROPN
bjos-8661512	25	7	2	2	NUM
bjos-8661512	25	8	amorim	amorim	NOUN
bjos-8661512	25	9	et	et	PROPN
bjos-8661512	26	1	al	al	PROPN
bjos-8661512	26	2	.	.	PROPN
bjos-8661512	26	3	introduction	introduction	NOUN
bjos-8661512	26	4	bone	bone	NOUN
bjos-8661512	26	5	remodeling	remodeling	NOUN
bjos-8661512	26	6	is	be	AUX
bjos-8661512	26	7	a	a	DET
bjos-8661512	26	8	process	process	NOUN
bjos-8661512	26	9	balanced	balance	VERB
bjos-8661512	26	10	between	between	ADP
bjos-8661512	26	11	osteoblast	osteoblast	ADV
bjos-8661512	26	12	-	-	PUNCT
bjos-8661512	26	13	mediated	mediate	VERB
bjos-8661512	26	14	bone	bone	NOUN
bjos-8661512	26	15	deposition	deposition	NOUN
bjos-8661512	26	16	and	and	CCONJ
bjos-8661512	26	17	osteoclast	osteoclast	ADV
bjos-8661512	26	18	-	-	PUNCT
bjos-8661512	26	19	developed	develop	VERB
bjos-8661512	26	20	bone	bone	NOUN
bjos-8661512	26	21	resorption	resorption	NOUN
bjos-8661512	26	22	.	.	PUNCT
bjos-8661512	27	1	many	many	ADJ
bjos-8661512	27	2	oral	oral	ADJ
bjos-8661512	27	3	diseases	disease	NOUN
bjos-8661512	27	4	are	be	AUX
bjos-8661512	27	5	mediated	mediate	VERB
bjos-8661512	27	6	by	by	ADP
bjos-8661512	27	7	an	an	DET
bjos-8661512	27	8	inflammatory	inflammatory	ADJ
bjos-8661512	27	9	process	process	NOUN
bjos-8661512	27	10	,	,	PUNCT
bjos-8661512	27	11	increasing	increase	VERB
bjos-8661512	27	12	the	the	DET
bjos-8661512	27	13	recruitment	recruitment	NOUN
bjos-8661512	27	14	of	of	ADP
bjos-8661512	27	15	osteoclasts	osteoclast	NOUN
bjos-8661512	27	16	and	and	CCONJ
bjos-8661512	27	17	enhancing	enhance	VERB
bjos-8661512	27	18	bone	bone	NOUN
bjos-8661512	27	19	erosion1	erosion1	PROPN
bjos-8661512	27	20	.	.	PUNCT
bjos-8661512	28	1	periodontal	periodontal	ADJ
bjos-8661512	28	2	disease	disease	NOUN
bjos-8661512	28	3	and	and	CCONJ
bjos-8661512	28	4	apical	apical	ADJ
bjos-8661512	28	5	periodontitis	periodontitis	NOUN
bjos-8661512	28	6	present	present	ADJ
bjos-8661512	28	7	bone	bone	NOUN
bjos-8661512	28	8	resorption	resorption	NOUN
bjos-8661512	28	9	with	with	ADP
bjos-8661512	28	10	high	high	ADJ
bjos-8661512	28	11	osteoclast	osteoclast	ADJ
bjos-8661512	28	12	formation	formation	NOUN
bjos-8661512	28	13	or	or	CCONJ
bjos-8661512	28	14	hyperactivation	hyperactivation	NOUN
bjos-8661512	28	15	,	,	PUNCT
bjos-8661512	28	16	overcoming	overcome	VERB
bjos-8661512	28	17	bone	bone	NOUN
bjos-8661512	28	18	formation	formation	NOUN
bjos-8661512	28	19	,	,	PUNCT
bjos-8661512	28	20	and	and	CCONJ
bjos-8661512	28	21	decreasing	decrease	VERB
bjos-8661512	28	22	osteoblast	osteoblast	ADJ
bjos-8661512	28	23	activity2	activity2	NOUN
bjos-8661512	28	24	.	.	PUNCT
bjos-8661512	29	1	inflammatory	inflammatory	ADJ
bjos-8661512	29	2	conditions	condition	NOUN
bjos-8661512	29	3	,	,	PUNCT
bjos-8661512	29	4	such	such	ADJ
bjos-8661512	29	5	as	as	ADP
bjos-8661512	29	6	local	local	ADJ
bjos-8661512	29	7	osteolysis	osteolysis	NOUN
bjos-8661512	29	8	,	,	PUNCT
bjos-8661512	29	9	can	can	AUX
bjos-8661512	29	10	be	be	AUX
bjos-8661512	29	11	associated	associate	VERB
bjos-8661512	29	12	with	with	ADP
bjos-8661512	29	13	inducible	inducible	ADJ
bjos-8661512	29	14	nitric	nitric	ADJ
bjos-8661512	29	15	oxide	oxide	NOUN
bjos-8661512	29	16	synthase	synthase	NOUN
bjos-8661512	29	17	(	(	PUNCT
bjos-8661512	29	18	inos	ino	NOUN
bjos-8661512	29	19	)	)	PUNCT
bjos-8661512	29	20	activation3	activation3	PROPN
bjos-8661512	29	21	.	.	PUNCT
bjos-8661512	30	1	no	no	PRON
bjos-8661512	30	2	can	can	AUX
bjos-8661512	30	3	also	also	ADV
bjos-8661512	30	4	promote	promote	VERB
bjos-8661512	30	5	cytokine	cytokine	ADJ
bjos-8661512	30	6	production	production	NOUN
bjos-8661512	30	7	and	and	CCONJ
bjos-8661512	30	8	bone	bone	NOUN
bjos-8661512	30	9	turnover	turnover	NOUN
bjos-8661512	30	10	besides	besides	SCONJ
bjos-8661512	30	11	indirect	indirect	ADJ
bjos-8661512	30	12	induction	induction	NOUN
bjos-8661512	30	13	of	of	ADP
bjos-8661512	30	14	bone	bone	NOUN
bjos-8661512	30	15	resorption3	resorption3	X
bjos-8661512	30	16	.	.	PUNCT
bjos-8661512	31	1	in	in	ADP
bjos-8661512	31	2	this	this	DET
bjos-8661512	31	3	regard	regard	NOUN
bjos-8661512	31	4	,	,	PUNCT
bjos-8661512	31	5	periodontitis	periodontitis	NOUN
bjos-8661512	31	6	results	result	NOUN
bjos-8661512	31	7	in	in	ADP
bjos-8661512	31	8	higher	high	ADJ
bjos-8661512	31	9	production	production	NOUN
bjos-8661512	31	10	of	of	ADP
bjos-8661512	31	11	no	no	PRON
bjos-8661512	31	12	compared	compare	VERB
bjos-8661512	31	13	to	to	ADP
bjos-8661512	31	14	healthy	healthy	ADJ
bjos-8661512	31	15	gingiva4	gingiva4	PROPN
bjos-8661512	31	16	.	.	PUNCT
bjos-8661512	32	1	periodontal	periodontal	ADJ
bjos-8661512	32	2	treatment	treatment	NOUN
bjos-8661512	32	3	may	may	AUX
bjos-8661512	32	4	involve	involve	VERB
bjos-8661512	32	5	the	the	DET
bjos-8661512	32	6	use	use	NOUN
bjos-8661512	32	7	of	of	ADP
bjos-8661512	32	8	several	several	ADJ
bjos-8661512	32	9	systemic	systemic	ADJ
bjos-8661512	32	10	antibiotics	antibiotic	NOUN
bjos-8661512	32	11	such	such	ADJ
bjos-8661512	32	12	as	as	ADP
bjos-8661512	32	13	tetracycline	tetracycline	NOUN
bjos-8661512	32	14	(	(	PUNCT
bjos-8661512	32	15	minocycline	minocycline	NOUN
bjos-8661512	32	16	and	and	CCONJ
bjos-8661512	32	17	doxycycline	doxycycline	NOUN
bjos-8661512	32	18	)	)	PUNCT
bjos-8661512	32	19	as	as	ADP
bjos-8661512	32	20	adjuvants	adjuvant	NOUN
bjos-8661512	32	21	due	due	ADP
bjos-8661512	32	22	to	to	ADP
bjos-8661512	32	23	its	its	PRON
bjos-8661512	32	24	local	local	ADJ
bjos-8661512	32	25	distribution	distribution	NOUN
bjos-8661512	32	26	.	.	PUNCT
bjos-8661512	33	1	it	it	PRON
bjos-8661512	33	2	was	be	AUX
bjos-8661512	33	3	demonstrated	demonstrate	VERB
bjos-8661512	33	4	that	that	SCONJ
bjos-8661512	33	5	doxycycline	doxycycline	NOUN
bjos-8661512	33	6	hyclate	hyclate	NOUN
bjos-8661512	33	7	gel	gel	NOUN
bjos-8661512	33	8	(	(	PUNCT
bjos-8661512	33	9	local	local	ADJ
bjos-8661512	33	10	therapy	therapy	NOUN
bjos-8661512	33	11	)	)	PUNCT
bjos-8661512	33	12	could	could	AUX
bjos-8661512	33	13	aid	aid	VERB
bjos-8661512	33	14	in	in	ADP
bjos-8661512	33	15	scaling	scaling	NOUN
bjos-8661512	33	16	and	and	CCONJ
bjos-8661512	33	17	root	root	NOUN
bjos-8661512	33	18	planning	planning	NOUN
bjos-8661512	33	19	in	in	ADP
bjos-8661512	33	20	patients	patient	NOUN
bjos-8661512	33	21	with	with	ADP
bjos-8661512	33	22	moderate	moderate	ADJ
bjos-8661512	33	23	to	to	ADP
bjos-8661512	33	24	severe	severe	ADJ
bjos-8661512	33	25	chronic	chronic	ADJ
bjos-8661512	33	26	periodontitis	periodontitis	NOUN
bjos-8661512	33	27	,	,	PUNCT
bjos-8661512	33	28	but	but	CCONJ
bjos-8661512	33	29	the	the	DET
bjos-8661512	33	30	benefit	benefit	NOUN
bjos-8661512	33	31	is	be	AUX
bjos-8661512	33	32	still	still	ADV
bjos-8661512	33	33	uncertain5	uncertain5	PROPN
bjos-8661512	33	34	.	.	PUNCT
bjos-8661512	34	1	for	for	ADP
bjos-8661512	34	2	the	the	DET
bjos-8661512	34	3	endodontic	endodontic	ADJ
bjos-8661512	34	4	treatment	treatment	NOUN
bjos-8661512	34	5	,	,	PUNCT
bjos-8661512	34	6	the	the	DET
bjos-8661512	34	7	use	use	NOUN
bjos-8661512	34	8	of	of	ADP
bjos-8661512	34	9	calcium	calcium	NOUN
bjos-8661512	34	10	hydroxide	hydroxide	NOUN
bjos-8661512	34	11	(	(	PUNCT
bjos-8661512	34	12	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	34	13	)	)	PUNCT
bjos-8661512	34	14	as	as	ADP
bjos-8661512	34	15	a	a	DET
bjos-8661512	34	16	local	local	ADJ
bjos-8661512	34	17	antimicrobial	antimicrobial	NOUN
bjos-8661512	34	18	is	be	AUX
bjos-8661512	34	19	accepted	accept	VERB
bjos-8661512	34	20	worldwide	worldwide	ADV
bjos-8661512	34	21	as	as	ADP
bjos-8661512	34	22	intracanal	intracanal	ADJ
bjos-8661512	34	23	dressing6	dressing6	NOUN
bjos-8661512	34	24	.	.	PUNCT
bjos-8661512	35	1	despite	despite	SCONJ
bjos-8661512	35	2	the	the	DET
bjos-8661512	35	3	high	high	ADJ
bjos-8661512	35	4	success	success	NOUN
bjos-8661512	35	5	rate	rate	NOUN
bjos-8661512	35	6	in	in	ADP
bjos-8661512	35	7	existing	exist	VERB
bjos-8661512	35	8	periodontal	periodontal	ADJ
bjos-8661512	35	9	and	and	CCONJ
bjos-8661512	35	10	endodontic	endodontic	ADJ
bjos-8661512	35	11	therapies	therapy	NOUN
bjos-8661512	35	12	,	,	PUNCT
bjos-8661512	35	13	there	there	PRON
bjos-8661512	35	14	are	be	VERB
bjos-8661512	35	15	some	some	DET
bjos-8661512	35	16	limitations	limitation	NOUN
bjos-8661512	35	17	,	,	PUNCT
bjos-8661512	35	18	mainly	mainly	ADV
bjos-8661512	35	19	in	in	ADP
bjos-8661512	35	20	tissue	tissue	NOUN
bjos-8661512	35	21	repair	repair	NOUN
bjos-8661512	35	22	activity6	activity6	NOUN
bjos-8661512	35	23	.	.	PUNCT
bjos-8661512	36	1	to	to	PART
bjos-8661512	36	2	improve	improve	VERB
bjos-8661512	36	3	bone	bone	NOUN
bjos-8661512	36	4	repair	repair	NOUN
bjos-8661512	36	5	in	in	ADP
bjos-8661512	36	6	these	these	DET
bjos-8661512	36	7	diseases	disease	NOUN
bjos-8661512	36	8	,	,	PUNCT
bjos-8661512	36	9	it	it	PRON
bjos-8661512	36	10	is	be	AUX
bjos-8661512	36	11	essential	essential	ADJ
bjos-8661512	36	12	to	to	PART
bjos-8661512	36	13	develop	develop	VERB
bjos-8661512	36	14	new	new	ADJ
bjos-8661512	36	15	substances	substance	NOUN
bjos-8661512	36	16	.	.	PUNCT
bjos-8661512	37	1	new	new	ADJ
bjos-8661512	37	2	therapies	therapy	NOUN
bjos-8661512	37	3	involving	involve	VERB
bjos-8661512	37	4	a	a	DET
bjos-8661512	37	5	direct	direct	ADJ
bjos-8661512	37	6	effect	effect	NOUN
bjos-8661512	37	7	on	on	ADP
bjos-8661512	37	8	the	the	DET
bjos-8661512	37	9	bone	bone	NOUN
bjos-8661512	37	10	can	can	AUX
bjos-8661512	37	11	prolong	prolong	VERB
bjos-8661512	37	12	the	the	DET
bjos-8661512	37	13	maintenance	maintenance	NOUN
bjos-8661512	37	14	of	of	ADP
bjos-8661512	37	15	the	the	DET
bjos-8661512	37	16	tooth	tooth	NOUN
bjos-8661512	37	17	in	in	ADP
bjos-8661512	37	18	the	the	DET
bjos-8661512	37	19	oral	oral	ADJ
bjos-8661512	37	20	cavity	cavity	NOUN
bjos-8661512	37	21	due	due	ADP
bjos-8661512	37	22	to	to	ADP
bjos-8661512	37	23	tissue	tissue	NOUN
bjos-8661512	37	24	support	support	NOUN
bjos-8661512	37	25	health	health	NOUN
bjos-8661512	37	26	.	.	PUNCT
bjos-8661512	38	1	host	host	NOUN
bjos-8661512	38	2	defense	defense	NOUN
bjos-8661512	38	3	peptides	peptide	NOUN
bjos-8661512	38	4	(	(	PUNCT
bjos-8661512	38	5	hdps	hdps	ADV
bjos-8661512	38	6	)	)	PUNCT
bjos-8661512	38	7	are	be	AUX
bjos-8661512	38	8	biomolecules	biomolecule	NOUN
bjos-8661512	38	9	from	from	ADP
bjos-8661512	38	10	many	many	ADJ
bjos-8661512	38	11	organisms	organism	NOUN
bjos-8661512	38	12	released	release	VERB
bjos-8661512	38	13	in	in	ADP
bjos-8661512	38	14	early	early	ADJ
bjos-8661512	38	15	defense	defense	NOUN
bjos-8661512	38	16	response	response	NOUN
bjos-8661512	38	17	to	to	ADP
bjos-8661512	38	18	infection	infection	NOUN
bjos-8661512	38	19	and	and	CCONJ
bjos-8661512	38	20	invasion	invasion	NOUN
bjos-8661512	38	21	by	by	ADP
bjos-8661512	38	22	bacteria	bacteria	NOUN
bjos-8661512	38	23	and	and	CCONJ
bjos-8661512	38	24	other	other	ADJ
bjos-8661512	38	25	microorganisms7	microorganisms7	PROPN
bjos-8661512	38	26	.	.	PUNCT
bjos-8661512	39	1	hdps	hdps	PROPN
bjos-8661512	39	2	may	may	AUX
bjos-8661512	39	3	possess	possess	VERB
bjos-8661512	39	4	antimicrobial	antimicrobial	ADJ
bjos-8661512	39	5	and	and	CCONJ
bjos-8661512	39	6	immunomodulatory	immunomodulatory	ADJ
bjos-8661512	39	7	properties	property	NOUN
bjos-8661512	39	8	besides	besides	SCONJ
bjos-8661512	39	9	tissue	tissue	NOUN
bjos-8661512	39	10	repair	repair	NOUN
bjos-8661512	39	11	induction8	induction8	NOUN
bjos-8661512	39	12	.	.	PUNCT
bjos-8661512	40	1	in	in	ADP
bjos-8661512	40	2	this	this	DET
bjos-8661512	40	3	context	context	NOUN
bjos-8661512	40	4	,	,	PUNCT
bjos-8661512	40	5	human	human	ADJ
bjos-8661512	40	6	cells	cell	NOUN
bjos-8661512	40	7	can	can	AUX
bjos-8661512	40	8	be	be	AUX
bjos-8661512	40	9	potential	potential	ADJ
bjos-8661512	40	10	sources	source	NOUN
bjos-8661512	40	11	of	of	ADP
bjos-8661512	40	12	hdps7	hdps7	PROPN
bjos-8661512	40	13	.	.	PUNCT
bjos-8661512	41	1	clavanin	clavanin	PROPN
bjos-8661512	41	2	a	a	PRON
bjos-8661512	41	3	is	be	AUX
bjos-8661512	41	4	a	a	DET
bjos-8661512	41	5	promising	promising	ADJ
bjos-8661512	41	6	hdp	hdp	NOUN
bjos-8661512	41	7	due	due	ADP
bjos-8661512	41	8	to	to	ADP
bjos-8661512	41	9	its	its	PRON
bjos-8661512	41	10	known	know	VERB
bjos-8661512	41	11	antibacterial	antibacterial	ADJ
bjos-8661512	41	12	,	,	PUNCT
bjos-8661512	41	13	immunomodulatory	immunomodulatory	NOUN
bjos-8661512	41	14	,	,	PUNCT
bjos-8661512	41	15	antitumor	antitumor	PROPN
bjos-8661512	41	16	,	,	PUNCT
bjos-8661512	41	17	and	and	CCONJ
bjos-8661512	41	18	antiviral	antiviral	ADJ
bjos-8661512	41	19	activities9	activities9	PROPN
bjos-8661512	41	20	.	.	PUNCT
bjos-8661512	42	1	besides	besides	SCONJ
bjos-8661512	42	2	,	,	PUNCT
bjos-8661512	42	3	clavanin	clavanin	NOUN
bjos-8661512	42	4	a	a	PRON
bjos-8661512	42	5	was	be	AUX
bjos-8661512	42	6	used	use	VERB
bjos-8661512	42	7	as	as	ADP
bjos-8661512	42	8	a	a	DET
bjos-8661512	42	9	model	model	NOUN
bjos-8661512	42	10	to	to	PART
bjos-8661512	42	11	create	create	VERB
bjos-8661512	42	12	clavanin	clavanin	PROPN
bjos-8661512	42	13	mo	mo	PROPN
bjos-8661512	42	14	.	.	PROPN
bjos-8661512	42	15	five	five	NUM
bjos-8661512	42	16	hydrophobic	hydrophobic	NOUN
bjos-8661512	42	17	amino	amino	NOUN
bjos-8661512	42	18	acid	acid	NOUN
bjos-8661512	42	19	residues	residue	NOUN
bjos-8661512	42	20	(	(	PUNCT
bjos-8661512	42	21	flpii	flpii	NOUN
bjos-8661512	42	22	)	)	PUNCT
bjos-8661512	42	23	were	be	AUX
bjos-8661512	42	24	added	add	VERB
bjos-8661512	42	25	to	to	ADP
bjos-8661512	42	26	the	the	DET
bjos-8661512	42	27	n	n	NOUN
bjos-8661512	42	28	-	-	PUNCT
bjos-8661512	42	29	terminus	terminus	NOUN
bjos-8661512	42	30	,	,	PUNCT
bjos-8661512	42	31	being	be	AUX
bjos-8661512	42	32	selected	select	VERB
bjos-8661512	42	33	based	base	VERB
bjos-8661512	42	34	on	on	ADP
bjos-8661512	42	35	a	a	DET
bjos-8661512	42	36	computational	computational	ADJ
bjos-8661512	42	37	search	search	NOUN
bjos-8661512	42	38	of	of	ADP
bjos-8661512	42	39	the	the	DET
bjos-8661512	42	40	conserved	conserved	ADJ
bjos-8661512	42	41	region	region	NOUN
bjos-8661512	42	42	of	of	ADP
bjos-8661512	42	43	other	other	ADJ
bjos-8661512	42	44	peptides	peptide	NOUN
bjos-8661512	42	45	with	with	ADP
bjos-8661512	42	46	higher	high	ADJ
bjos-8661512	42	47	immunomodulatory	immunomodulatory	ADJ
bjos-8661512	42	48	activities10	activities10	NOUN
bjos-8661512	42	49	.	.	PUNCT
bjos-8661512	43	1	it	it	PRON
bjos-8661512	43	2	has	have	AUX
bjos-8661512	43	3	been	be	AUX
bjos-8661512	43	4	shown	show	VERB
bjos-8661512	43	5	that	that	SCONJ
bjos-8661512	43	6	different	different	ADJ
bjos-8661512	43	7	hdps	hdps	NOUN
bjos-8661512	43	8	could	could	AUX
bjos-8661512	43	9	improve	improve	VERB
bjos-8661512	43	10	therapies	therapy	NOUN
bjos-8661512	43	11	in	in	ADP
bjos-8661512	43	12	the	the	DET
bjos-8661512	43	13	dental	dental	ADJ
bjos-8661512	43	14	field	field	NOUN
bjos-8661512	43	15	.	.	PUNCT
bjos-8661512	44	1	some	some	DET
bjos-8661512	44	2	peptides	peptide	NOUN
bjos-8661512	44	3	have	have	AUX
bjos-8661512	44	4	been	be	AUX
bjos-8661512	44	5	reported	report	VERB
bjos-8661512	44	6	as	as	ADP
bjos-8661512	44	7	having	have	VERB
bjos-8661512	44	8	the	the	DET
bjos-8661512	44	9	potential	potential	NOUN
bjos-8661512	44	10	to	to	PART
bjos-8661512	44	11	inhibit	inhibit	VERB
bjos-8661512	44	12	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	44	13	such	such	ADJ
bjos-8661512	44	14	as	as	ADP
bjos-8661512	44	15	ll-3711	ll-3711	NOUN
bjos-8661512	44	16	,	,	PUNCT
bjos-8661512	44	17	human	human	ADJ
bjos-8661512	44	18	beta	beta	NOUN
bjos-8661512	44	19	-	-	PUNCT
bjos-8661512	44	20	defensin-3	defensin-3	NOUN
bjos-8661512	44	21	with	with	ADP
bjos-8661512	44	22	c	c	NOUN
bjos-8661512	44	23	-	-	PUNCT
bjos-8661512	44	24	terminal	terminal	ADJ
bjos-8661512	44	25	end	end	NOUN
bjos-8661512	44	26	contains	contain	VERB
bjos-8661512	44	27	a	a	DET
bjos-8661512	44	28	15	15	NUM
bjos-8661512	44	29	-	-	PUNCT
bjos-8661512	44	30	amino	amino	NOUN
bjos-8661512	44	31	acid	acid	NOUN
bjos-8661512	44	32	polypeptide	polypeptide	ADJ
bjos-8661512	44	33	(	(	PUNCT
bjos-8661512	44	34	hbd3	hbd3	PROPN
bjos-8661512	44	35	c15)12	c15)12	NOUN
bjos-8661512	44	36	,	,	PUNCT
bjos-8661512	44	37	synoeca	synoeca	NOUN
bjos-8661512	44	38	-	-	PUNCT
bjos-8661512	44	39	mp,13	mp,13	NOUN
bjos-8661512	44	40	and	and	CCONJ
bjos-8661512	44	41	hhc-1013	hhc-1013	NOUN
bjos-8661512	44	42	.	.	PUNCT
bjos-8661512	45	1	a	a	DET
bjos-8661512	45	2	previous	previous	ADJ
bjos-8661512	45	3	study	study	NOUN
bjos-8661512	45	4	demonstrated	demonstrate	VERB
bjos-8661512	45	5	that	that	SCONJ
bjos-8661512	45	6	ll-37	ll-37	NOUN
bjos-8661512	45	7	and	and	CCONJ
bjos-8661512	45	8	clavanins	clavanin	NOUN
bjos-8661512	45	9	a	a	PRON
bjos-8661512	45	10	and	and	CCONJ
bjos-8661512	45	11	mo	mo	PROPN
bjos-8661512	45	12	can	can	AUX
bjos-8661512	45	13	modulate	modulate	VERB
bjos-8661512	45	14	the	the	DET
bjos-8661512	45	15	inflammatory	inflammatory	ADJ
bjos-8661512	45	16	response	response	NOUN
bjos-8661512	45	17	of	of	ADP
bjos-8661512	45	18	active	active	ADJ
bjos-8661512	45	19	cytokines	cytokine	NOUN
bjos-8661512	45	20	presented	present	VERB
bjos-8661512	45	21	in	in	ADP
bjos-8661512	45	22	the	the	DET
bjos-8661512	45	23	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	45	24	process	process	NOUN
bjos-8661512	45	25	,	,	PUNCT
bjos-8661512	45	26	such	such	ADJ
bjos-8661512	45	27	as	as	ADP
bjos-8661512	45	28	tnf	tnf	PROPN
bjos-8661512	45	29	-	-	PUNCT
bjos-8661512	45	30	α	α	PROPN
bjos-8661512	45	31	,	,	PUNCT
bjos-8661512	45	32	while	while	SCONJ
bjos-8661512	45	33	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	45	34	up	up	ADV
bjos-8661512	45	35	-	-	PUNCT
bjos-8661512	45	36	regulated	regulate	VERB
bjos-8661512	45	37	the	the	DET
bjos-8661512	45	38	il-6	il-6	NOUN
bjos-8661512	45	39	and	and	CCONJ
bjos-8661512	45	40	il-1α	il-1α	PROPN
bjos-8661512	45	41	production14	production14	NOUN
bjos-8661512	45	42	.	.	PUNCT
bjos-8661512	46	1	this	this	DET
bjos-8661512	46	2	fact	fact	NOUN
bjos-8661512	46	3	leads	lead	VERB
bjos-8661512	46	4	us	we	PRON
bjos-8661512	46	5	to	to	PART
bjos-8661512	46	6	believe	believe	VERB
bjos-8661512	46	7	that	that	SCONJ
bjos-8661512	46	8	clavanins	clavanin	NOUN
bjos-8661512	46	9	a	a	PRON
bjos-8661512	46	10	and	and	CCONJ
bjos-8661512	46	11	mo	mo	PROPN
bjos-8661512	46	12	may	may	AUX
bjos-8661512	46	13	have	have	VERB
bjos-8661512	46	14	the	the	DET
bjos-8661512	46	15	potential	potential	NOUN
bjos-8661512	46	16	to	to	PART
bjos-8661512	46	17	inhibit	inhibit	VERB
bjos-8661512	46	18	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	46	19	,	,	PUNCT
bjos-8661512	46	20	a	a	DET
bjos-8661512	46	21	fact	fact	NOUN
bjos-8661512	46	22	that	that	PRON
bjos-8661512	46	23	has	have	AUX
bjos-8661512	46	24	not	not	PART
bjos-8661512	46	25	yet	yet	ADV
bjos-8661512	46	26	been	be	AUX
bjos-8661512	46	27	evaluated	evaluate	VERB
bjos-8661512	46	28	.	.	PUNCT
bjos-8661512	47	1	thus	thus	ADV
bjos-8661512	47	2	,	,	PUNCT
bjos-8661512	47	3	this	this	DET
bjos-8661512	47	4	study	study	NOUN
bjos-8661512	47	5	aims	aim	VERB
bjos-8661512	47	6	to	to	PART
bjos-8661512	47	7	evaluate	evaluate	VERB
bjos-8661512	47	8	the	the	DET
bjos-8661512	47	9	biotechnological	biotechnological	ADJ
bjos-8661512	47	10	potential	potential	NOUN
bjos-8661512	47	11	of	of	ADP
bjos-8661512	47	12	hdps	hdps	PROPN
bjos-8661512	47	13	clavanin	clavanin	PROPN
bjos-8661512	47	14	a	a	PRON
bjos-8661512	47	15	and	and	CCONJ
bjos-8661512	47	16	mo	mo	NOUN
bjos-8661512	47	17	in	in	ADP
bjos-8661512	47	18	the	the	DET
bjos-8661512	47	19	oral	oral	ADJ
bjos-8661512	47	20	osteoimmunological	osteoimmunological	ADJ
bjos-8661512	47	21	context	context	NOUN
bjos-8661512	47	22	and	and	CCONJ
bjos-8661512	47	23	their	their	PRON
bjos-8661512	47	24	capability	capability	NOUN
bjos-8661512	47	25	to	to	PART
bjos-8661512	47	26	reduce	reduce	VERB
bjos-8661512	47	27	in	in	ADP
bjos-8661512	47	28	vitro	vitro	X
bjos-8661512	47	29	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	47	30	,	,	PUNCT
bjos-8661512	47	31	3	3	NUM
bjos-8661512	47	32	amorim	amorim	NOUN
bjos-8661512	47	33	et	et	PROPN
bjos-8661512	47	34	al	al	PROPN
bjos-8661512	47	35	.	.	PROPN
bjos-8661512	47	36	compared	compare	VERB
bjos-8661512	47	37	to	to	ADP
bjos-8661512	47	38	ll-37	ll-37	NOUN
bjos-8661512	47	39	(	(	PUNCT
bjos-8661512	47	40	hdp	hdp	PROPN
bjos-8661512	47	41	control	control	PROPN
bjos-8661512	47	42	)	)	PUNCT
bjos-8661512	47	43	,	,	PUNCT
bjos-8661512	47	44	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	47	45	(	(	PUNCT
bjos-8661512	47	46	used	use	VERB
bjos-8661512	47	47	in	in	ADP
bjos-8661512	47	48	the	the	DET
bjos-8661512	47	49	endodontic	endodontic	ADJ
bjos-8661512	47	50	treatment	treatment	NOUN
bjos-8661512	47	51	)	)	PUNCT
bjos-8661512	47	52	and	and	CCONJ
bjos-8661512	47	53	doxycycline	doxycycline	NOUN
bjos-8661512	47	54	(	(	PUNCT
bjos-8661512	47	55	used	use	VERB
bjos-8661512	47	56	in	in	ADP
bjos-8661512	47	57	the	the	DET
bjos-8661512	47	58	periodontal	periodontal	ADJ
bjos-8661512	47	59	treatment	treatment	NOUN
bjos-8661512	47	60	)	)	PUNCT
bjos-8661512	47	61	.	.	PUNCT
bjos-8661512	48	1	material	material	NOUN
bjos-8661512	48	2	and	and	CCONJ
bjos-8661512	48	3	methods	method	NOUN
bjos-8661512	48	4	peptide	peptide	VERB
bjos-8661512	48	5	synthesis	synthesis	NOUN
bjos-8661512	48	6	clavanin	clavanin	NOUN
bjos-8661512	48	7	a	a	DET
bjos-8661512	48	8	(	(	PUNCT
bjos-8661512	48	9	vfqflgkiihhvgnfvhgfshvf	vfqflgkiihhvgnfvhgfshvf	NOUN
bjos-8661512	48	10	-	-	PUNCT
bjos-8661512	48	11	nh2	nh2	NOUN
bjos-8661512	48	12	)	)	PUNCT
bjos-8661512	48	13	,	,	PUNCT
bjos-8661512	48	14	clavanin	clavanin	PROPN
bjos-8661512	48	15	mo	mo	PROPN
bjos-8661512	48	16	(	(	PUNCT
bjos-8661512	48	17	flpiivfqflgkiihhvgnfvhgfshvf	flpiivfqflgkiihhvgnfvhgfshvf	PROPN
bjos-8661512	48	18	-	-	PUNCT
bjos-8661512	48	19	nh2	nh2	NOUN
bjos-8661512	48	20	)	)	PUNCT
bjos-8661512	48	21	,	,	PUNCT
bjos-8661512	48	22	and	and	CCONJ
bjos-8661512	48	23	ll-37	ll-37	NOUN
bjos-8661512	48	24	(	(	PUNCT
bjos-8661512	48	25	llgdffrkskekigkefkrivqrikdflrnlvprtes	llgdffrkskekigkefkrivqrikdflrnlvprte	NOUN
bjos-8661512	48	26	-	-	PUNCT
bjos-8661512	48	27	nh2	nh2	NOUN
bjos-8661512	48	28	)	)	PUNCT
bjos-8661512	48	29	were	be	AUX
bjos-8661512	48	30	synthesized	synthesize	VERB
bjos-8661512	48	31	and	and	CCONJ
bjos-8661512	48	32	purified	purify	VERB
bjos-8661512	48	33	(	(	PUNCT
bjos-8661512	48	34	>	>	SYM
bjos-8661512	48	35	95	95	NUM
bjos-8661512	48	36	%	%	NOUN
bjos-8661512	48	37	purity	purity	NOUN
bjos-8661512	48	38	)	)	PUNCT
bjos-8661512	48	39	by	by	ADP
bjos-8661512	48	40	peptide	peptide	NOUN
bjos-8661512	48	41	2.0	2.0	NUM
bjos-8661512	48	42	inc	inc	PROPN
bjos-8661512	48	43	.	.	PROPN
bjos-8661512	48	44	(	(	PUNCT
bjos-8661512	48	45	usa	usa	PROPN
bjos-8661512	48	46	)	)	PUNCT
bjos-8661512	48	47	.	.	PUNCT
bjos-8661512	49	1	molecular	molecular	ADJ
bjos-8661512	49	2	mass	mass	NOUN
bjos-8661512	49	3	and	and	CCONJ
bjos-8661512	49	4	purity	purity	NOUN
bjos-8661512	49	5	of	of	ADP
bjos-8661512	49	6	all	all	DET
bjos-8661512	49	7	peptides	peptide	NOUN
bjos-8661512	49	8	were	be	AUX
bjos-8661512	49	9	analyzed	analyze	VERB
bjos-8661512	49	10	by	by	ADP
bjos-8661512	49	11	matrix	matrix	NOUN
bjos-8661512	49	12	-	-	PUNCT
bjos-8661512	49	13	assisted	assist	VERB
bjos-8661512	49	14	laser	laser	NOUN
bjos-8661512	49	15	desorption	desorption	NOUN
bjos-8661512	49	16	/	/	SYM
bjos-8661512	49	17	ionization	ionization	NOUN
bjos-8661512	49	18	time	time	NOUN
bjos-8661512	49	19	of	of	ADP
bjos-8661512	49	20	flight	flight	NOUN
bjos-8661512	49	21	mass	mass	NOUN
bjos-8661512	49	22	spectrometry	spectrometry	NOUN
bjos-8661512	49	23	on	on	ADP
bjos-8661512	49	24	an	an	DET
bjos-8661512	49	25	auto	auto	NOUN
bjos-8661512	49	26	-	-	PUNCT
bjos-8661512	49	27	flex	flex	ADJ
bjos-8661512	49	28	iii	iii	NOUN
bjos-8661512	49	29	speed	speed	NOUN
bjos-8661512	49	30	instrument	instrument	NOUN
bjos-8661512	49	31	(	(	PUNCT
bjos-8661512	49	32	bruker	bruker	PROPN
bjos-8661512	49	33	daltonics	daltonics	PROPN
bjos-8661512	49	34	,	,	PUNCT
bjos-8661512	49	35	billerica	billerica	PROPN
bjos-8661512	49	36	,	,	PUNCT
bjos-8661512	49	37	ma	ma	PROPN
bjos-8661512	49	38	)	)	PUNCT
bjos-8661512	49	39	.	.	PUNCT
bjos-8661512	50	1	peptides	peptide	NOUN
bjos-8661512	50	2	were	be	AUX
bjos-8661512	50	3	diluted	dilute	VERB
bjos-8661512	50	4	in	in	ADP
bjos-8661512	50	5	ultrapure	ultrapure	ADJ
bjos-8661512	50	6	water	water	NOUN
bjos-8661512	50	7	and	and	CCONJ
bjos-8661512	50	8	quantified	quantify	VERB
bjos-8661512	50	9	by	by	ADP
bjos-8661512	50	10	uv	uv	NOUN
bjos-8661512	50	11	absorption	absorption	NOUN
bjos-8661512	50	12	at	at	ADP
bjos-8661512	50	13	205	205	NUM
bjos-8661512	50	14	,	,	PUNCT
bjos-8661512	50	15	215	215	NUM
bjos-8661512	50	16	,	,	PUNCT
bjos-8661512	50	17	and	and	CCONJ
bjos-8661512	50	18	225	225	NUM
bjos-8661512	50	19	nm	nm	NOUN
bjos-8661512	50	20	,	,	PUNCT
bjos-8661512	50	21	according	accord	VERB
bjos-8661512	50	22	to	to	ADP
bjos-8661512	50	23	murphy	murphy	PROPN
bjos-8661512	50	24	and	and	CCONJ
bjos-8661512	50	25	kies15	kies15	PROPN
bjos-8661512	50	26	.	.	PUNCT
bjos-8661512	51	1	doxycycline	doxycycline	NOUN
bjos-8661512	51	2	and	and	CCONJ
bjos-8661512	51	3	calcium	calcium	NOUN
bjos-8661512	51	4	hydroxide	hydroxide	NOUN
bjos-8661512	51	5	preparation	preparation	NOUN
bjos-8661512	51	6	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	51	7	(	(	PUNCT
bjos-8661512	51	8	iodontosul	iodontosul	PROPN
bjos-8661512	51	9	,	,	PUNCT
bjos-8661512	51	10	porto	porto	PROPN
bjos-8661512	51	11	alegre	alegre	PROPN
bjos-8661512	51	12	,	,	PUNCT
bjos-8661512	51	13	brazil	brazil	PROPN
bjos-8661512	51	14	)	)	PUNCT
bjos-8661512	51	15	was	be	AUX
bjos-8661512	51	16	weighed	weigh	VERB
bjos-8661512	51	17	and	and	CCONJ
bjos-8661512	51	18	diluted	dilute	VERB
bjos-8661512	51	19	in	in	ADP
bjos-8661512	51	20	ultrapure	ultrapure	ADJ
bjos-8661512	51	21	water	water	NOUN
bjos-8661512	51	22	before	before	ADP
bjos-8661512	51	23	each	each	DET
bjos-8661512	51	24	experiment	experiment	NOUN
bjos-8661512	51	25	.	.	PUNCT
bjos-8661512	52	1	doxycycline	doxycycline	NOUN
bjos-8661512	52	2	(	(	PUNCT
bjos-8661512	52	3	pharmac	pharmac	NOUN
bjos-8661512	52	4	,	,	PUNCT
bjos-8661512	52	5	brasilia	brasilia	PROPN
bjos-8661512	52	6	,	,	PUNCT
bjos-8661512	52	7	brazil	brazil	PROPN
bjos-8661512	52	8	)	)	PUNCT
bjos-8661512	52	9	was	be	AUX
bjos-8661512	52	10	handled	handle	VERB
bjos-8661512	52	11	in	in	ADP
bjos-8661512	52	12	capsules	capsule	NOUN
bjos-8661512	52	13	(	(	PUNCT
bjos-8661512	52	14	100	100	NUM
bjos-8661512	52	15	mg	mg	NOUN
bjos-8661512	52	16	in	in	ADP
bjos-8661512	52	17	each	each	DET
bjos-8661512	52	18	unit	unit	NOUN
bjos-8661512	52	19	)	)	PUNCT
bjos-8661512	52	20	.	.	PUNCT
bjos-8661512	53	1	the	the	DET
bjos-8661512	53	2	capsules	capsule	NOUN
bjos-8661512	53	3	were	be	AUX
bjos-8661512	53	4	opened	open	VERB
bjos-8661512	53	5	,	,	PUNCT
bjos-8661512	53	6	and	and	CCONJ
bjos-8661512	53	7	doxycycline	doxycycline	NOUN
bjos-8661512	53	8	was	be	AUX
bjos-8661512	53	9	weighed	weigh	VERB
bjos-8661512	53	10	and	and	CCONJ
bjos-8661512	53	11	diluted	dilute	VERB
bjos-8661512	53	12	in	in	ADP
bjos-8661512	53	13	ultrapure	ultrapure	ADJ
bjos-8661512	53	14	water	water	NOUN
bjos-8661512	53	15	before	before	ADP
bjos-8661512	53	16	each	each	DET
bjos-8661512	53	17	experiment	experiment	NOUN
bjos-8661512	53	18	.	.	PUNCT
bjos-8661512	54	1	cell	cell	NOUN
bjos-8661512	54	2	culture	culture	NOUN
bjos-8661512	54	3	,	,	PUNCT
bjos-8661512	54	4	experimental	experimental	ADJ
bjos-8661512	54	5	groups	group	NOUN
bjos-8661512	54	6	and	and	CCONJ
bjos-8661512	54	7	osteoclasts	osteoclast	NOUN
bjos-8661512	54	8	osteoclast	osteoclast	VERB
bjos-8661512	54	9	precursor	precursor	NOUN
bjos-8661512	54	10	raw	raw	ADJ
bjos-8661512	54	11	264.7	264.7	NUM
bjos-8661512	54	12	cell	cell	NOUN
bjos-8661512	54	13	line	line	NOUN
bjos-8661512	54	14	(	(	PUNCT
bjos-8661512	54	15	raw	raw	ADJ
bjos-8661512	54	16	;	;	PUNCT
bjos-8661512	54	17	bcrj	bcrj	NOUN
bjos-8661512	54	18	code	code	PROPN
bjos-8661512	54	19	0212	0212	NUM
bjos-8661512	54	20	;	;	PUNCT
bjos-8661512	54	21	rrid	rrid	VERB
bjos-8661512	54	22	cvcl_0493	cvcl_0493	PROPN
bjos-8661512	54	23	–	–	PUNCT
bjos-8661512	54	24	rio	rio	PROPN
bjos-8661512	54	25	de	de	PROPN
bjos-8661512	54	26	janeiro	janeiro	PROPN
bjos-8661512	54	27	,	,	PUNCT
bjos-8661512	54	28	brazil	brazil	PROPN
bjos-8661512	54	29	)	)	PUNCT
bjos-8661512	54	30	is	be	AUX
bjos-8661512	54	31	composed	compose	VERB
bjos-8661512	54	32	of	of	ADP
bjos-8661512	54	33	monocytes	monocyte	NOUN
bjos-8661512	54	34	derived	derive	VERB
bjos-8661512	54	35	from	from	ADP
bjos-8661512	54	36	tumors	tumor	NOUN
bjos-8661512	54	37	induced	induce	VERB
bjos-8661512	54	38	in	in	ADP
bjos-8661512	54	39	male	male	ADJ
bjos-8661512	54	40	balb	balb	NOUN
bjos-8661512	54	41	/	/	SYM
bjos-8661512	54	42	c	c	NOUN
bjos-8661512	54	43	mice	mouse	NOUN
bjos-8661512	54	44	(	(	PUNCT
bjos-8661512	54	45	mus	mus	PROPN
bjos-8661512	54	46	musculus	musculus	PROPN
bjos-8661512	54	47	)	)	PUNCT
bjos-8661512	54	48	,	,	PUNCT
bjos-8661512	54	49	infected	infect	VERB
bjos-8661512	54	50	with	with	ADP
bjos-8661512	54	51	murine	murine	ADJ
bjos-8661512	54	52	leukemia	leukemia	PROPN
bjos-8661512	54	53	abelson	abelson	NOUN
bjos-8661512	54	54	virus16	virus16	PROPN
bjos-8661512	54	55	.	.	PUNCT
bjos-8661512	55	1	raw	raw	ADJ
bjos-8661512	55	2	cells	cell	NOUN
bjos-8661512	55	3	were	be	AUX
bjos-8661512	55	4	grown	grow	VERB
bjos-8661512	55	5	in	in	ADP
bjos-8661512	55	6	high	high	ADJ
bjos-8661512	55	7	glucose	glucose	NOUN
bjos-8661512	55	8	dulbecco	dulbecco	NOUN
bjos-8661512	55	9	’s	’s	PART
bjos-8661512	55	10	modified	modified	PROPN
bjos-8661512	55	11	eagle	eagle	PROPN
bjos-8661512	55	12	’s	’s	PART
bjos-8661512	55	13	medium	medium	NOUN
bjos-8661512	55	14	(	(	PUNCT
bjos-8661512	55	15	dmem	dmem	ADJ
bjos-8661512	55	16	;	;	PUNCT
bjos-8661512	55	17	gibco	gibco	PROPN
bjos-8661512	55	18	,	,	PUNCT
bjos-8661512	55	19	california	california	PROPN
bjos-8661512	55	20	,	,	PUNCT
bjos-8661512	55	21	usa	usa	PROPN
bjos-8661512	55	22	)	)	PUNCT
bjos-8661512	55	23	supplemented	supplement	VERB
bjos-8661512	55	24	with	with	ADP
bjos-8661512	55	25	10	10	NUM
bjos-8661512	55	26	%	%	NOUN
bjos-8661512	55	27	fetal	fetal	ADJ
bjos-8661512	55	28	bovine	bovine	NOUN
bjos-8661512	55	29	serum	serum	NOUN
bjos-8661512	55	30	(	(	PUNCT
bjos-8661512	55	31	gibco	gibco	PROPN
bjos-8661512	55	32	,	,	PUNCT
bjos-8661512	55	33	california	california	PROPN
bjos-8661512	55	34	,	,	PUNCT
bjos-8661512	55	35	usa	usa	PROPN
bjos-8661512	55	36	)	)	PUNCT
bjos-8661512	55	37	,	,	PUNCT
bjos-8661512	55	38	1	1	NUM
bjos-8661512	55	39	%	%	NOUN
bjos-8661512	55	40	penicillin	penicillin	NOUN
bjos-8661512	55	41	/	/	SYM
bjos-8661512	55	42	streptomycin	streptomycin	PROPN
bjos-8661512	55	43	(	(	PUNCT
bjos-8661512	55	44	1000	1000	NUM
bjos-8661512	55	45	u.ml-1	u.ml-1	NUM
bjos-8661512	55	46	)	)	PUNCT
bjos-8661512	55	47	(	(	PUNCT
bjos-8661512	55	48	gibco	gibco	NOUN
bjos-8661512	55	49	,	,	PUNCT
bjos-8661512	55	50	california	california	PROPN
bjos-8661512	55	51	,	,	PUNCT
bjos-8661512	55	52	usa	usa	PROPN
bjos-8661512	55	53	)	)	PUNCT
bjos-8661512	55	54	,	,	PUNCT
bjos-8661512	55	55	1	1	NUM
bjos-8661512	55	56	%	%	NOUN
bjos-8661512	55	57	nonessential	nonessential	ADJ
bjos-8661512	55	58	amino	amino	NOUN
bjos-8661512	55	59	acid	acid	NOUN
bjos-8661512	55	60	solution	solution	NOUN
bjos-8661512	55	61	(	(	PUNCT
bjos-8661512	55	62	gibco	gibco	NOUN
bjos-8661512	55	63	,	,	PUNCT
bjos-8661512	55	64	california	california	PROPN
bjos-8661512	55	65	,	,	PUNCT
bjos-8661512	55	66	usa	usa	PROPN
bjos-8661512	55	67	)	)	PUNCT
bjos-8661512	55	68	,	,	PUNCT
bjos-8661512	55	69	1	1	NUM
bjos-8661512	55	70	%	%	NOUN
bjos-8661512	55	71	l	l	NOUN
bjos-8661512	55	72	-	-	NOUN
bjos-8661512	55	73	glutamine	glutamine	NOUN
bjos-8661512	55	74	(	(	PUNCT
bjos-8661512	55	75	gibco	gibco	PROPN
bjos-8661512	55	76	,	,	PUNCT
bjos-8661512	55	77	california	california	PROPN
bjos-8661512	55	78	,	,	PUNCT
bjos-8661512	55	79	usa	usa	PROPN
bjos-8661512	55	80	)	)	PUNCT
bjos-8661512	55	81	and	and	CCONJ
bjos-8661512	55	82	0.1	0.1	NUM
bjos-8661512	55	83	%	%	NOUN
bjos-8661512	55	84	gentamicin	gentamicin	NOUN
bjos-8661512	55	85	(	(	PUNCT
bjos-8661512	55	86	gibco	gibco	PROPN
bjos-8661512	55	87	,	,	PUNCT
bjos-8661512	55	88	california	california	PROPN
bjos-8661512	55	89	,	,	PUNCT
bjos-8661512	55	90	usa	usa	PROPN
bjos-8661512	55	91	)	)	PUNCT
bjos-8661512	55	92	.	.	PUNCT
bjos-8661512	56	1	cell	cell	NOUN
bjos-8661512	56	2	cultures	culture	NOUN
bjos-8661512	56	3	were	be	AUX
bjos-8661512	56	4	maintained	maintain	VERB
bjos-8661512	56	5	in	in	ADP
bjos-8661512	56	6	an	an	DET
bjos-8661512	56	7	incubator	incubator	NOUN
bjos-8661512	56	8	containing	contain	VERB
bjos-8661512	56	9	5	5	NUM
bjos-8661512	56	10	%	%	NOUN
bjos-8661512	56	11	co2	co2	NOUN
bjos-8661512	56	12	at	at	ADP
bjos-8661512	56	13	37	37	NUM
bjos-8661512	56	14	°	°	ADP
bjos-8661512	56	15	c	c	NOUN
bjos-8661512	56	16	and	and	CCONJ
bjos-8661512	56	17	95	95	NUM
bjos-8661512	56	18	%	%	NOUN
bjos-8661512	56	19	humidity	humidity	NOUN
bjos-8661512	56	20	.	.	PUNCT
bjos-8661512	57	1	experiments	experiment	NOUN
bjos-8661512	57	2	were	be	AUX
bjos-8661512	57	3	conducted	conduct	VERB
bjos-8661512	57	4	with	with	ADP
bjos-8661512	57	5	2.5x103	2.5x103	ADJ
bjos-8661512	57	6	cells	cell	NOUN
bjos-8661512	57	7	per	per	ADP
bjos-8661512	57	8	wells	well	NOUN
bjos-8661512	57	9	in	in	ADP
bjos-8661512	57	10	96	96	NUM
bjos-8661512	57	11	-	-	PUNCT
bjos-8661512	57	12	well	well	NOUN
bjos-8661512	57	13	plates	plate	NOUN
bjos-8661512	57	14	(	(	PUNCT
bjos-8661512	57	15	kasvi	kasvi	PROPN
bjos-8661512	57	16	,	,	PUNCT
bjos-8661512	57	17	china	china	PROPN
bjos-8661512	57	18	)	)	PUNCT
bjos-8661512	57	19	,	,	PUNCT
bjos-8661512	57	20	stimulated	stimulate	VERB
bjos-8661512	57	21	with	with	ADP
bjos-8661512	57	22	or	or	CCONJ
bjos-8661512	57	23	without	without	ADP
bjos-8661512	57	24	rrankl	rrankl	NOUN
bjos-8661512	57	25	100	100	NUM
bjos-8661512	57	26	ng.ml-1	ng.ml-1	ADJ
bjos-8661512	57	27	(	(	PUNCT
bjos-8661512	57	28	peprotech	peprotech	NOUN
bjos-8661512	57	29	,	,	PUNCT
bjos-8661512	57	30	new	new	PROPN
bjos-8661512	57	31	jersey	jersey	PROPN
bjos-8661512	57	32	,	,	PUNCT
bjos-8661512	57	33	usa	usa	PROPN
bjos-8661512	57	34	)	)	PUNCT
bjos-8661512	57	35	and	and	CCONJ
bjos-8661512	57	36	hdps	hdps	PROPN
bjos-8661512	57	37	clavanin	clavanin	PROPN
bjos-8661512	57	38	a	a	PRON
bjos-8661512	57	39	,	,	PUNCT
bjos-8661512	57	40	clavanin	clavanin	PROPN
bjos-8661512	57	41	mo	mo	PROPN
bjos-8661512	57	42	,	,	PUNCT
bjos-8661512	57	43	and	and	CCONJ
bjos-8661512	57	44	ll-37	ll-37	NOUN
bjos-8661512	57	45	(	(	PUNCT
bjos-8661512	57	46	2	2	NUM
bjos-8661512	57	47	,	,	PUNCT
bjos-8661512	57	48	8	8	NUM
bjos-8661512	57	49	,	,	PUNCT
bjos-8661512	57	50	32	32	NUM
bjos-8661512	57	51	,	,	PUNCT
bjos-8661512	57	52	and	and	CCONJ
bjos-8661512	57	53	128	128	NUM
bjos-8661512	57	54	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	57	55	)	)	PUNCT
bjos-8661512	57	56	.	.	PUNCT
bjos-8661512	58	1	peptide	peptide	PROPN
bjos-8661512	58	2	stimulated	stimulate	VERB
bjos-8661512	58	3	cultures	culture	NOUN
bjos-8661512	58	4	were	be	AUX
bjos-8661512	58	5	compared	compare	VERB
bjos-8661512	58	6	to	to	PART
bjos-8661512	58	7	doxycycline	doxycycline	VERB
bjos-8661512	58	8	and	and	CCONJ
bjos-8661512	58	9	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	58	10	(	(	PUNCT
bjos-8661512	58	11	2	2	NUM
bjos-8661512	58	12	,	,	PUNCT
bjos-8661512	58	13	8	8	NUM
bjos-8661512	58	14	,	,	PUNCT
bjos-8661512	58	15	32	32	NUM
bjos-8661512	58	16	,	,	PUNCT
bjos-8661512	58	17	and	and	CCONJ
bjos-8661512	58	18	128	128	NUM
bjos-8661512	58	19	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	58	20	)	)	PUNCT
bjos-8661512	58	21	.	.	PUNCT
bjos-8661512	59	1	the	the	DET
bjos-8661512	59	2	concentrations	concentration	NOUN
bjos-8661512	59	3	were	be	AUX
bjos-8661512	59	4	based	base	VERB
bjos-8661512	59	5	on	on	ADP
bjos-8661512	59	6	a	a	DET
bjos-8661512	59	7	previously	previously	ADV
bjos-8661512	59	8	published	publish	VERB
bjos-8661512	59	9	result14	result14	NOUN
bjos-8661512	59	10	.	.	PUNCT
bjos-8661512	60	1	cell	cell	NOUN
bjos-8661512	60	2	viability	viability	NOUN
bjos-8661512	60	3	assay	assay	NOUN
bjos-8661512	60	4	and	and	CCONJ
bjos-8661512	60	5	no	no	DET
bjos-8661512	60	6	production	production	NOUN
bjos-8661512	60	7	were	be	AUX
bjos-8661512	60	8	analyzed	analyze	VERB
bjos-8661512	60	9	after	after	ADP
bjos-8661512	60	10	3	3	NUM
bjos-8661512	60	11	and	and	CCONJ
bjos-8661512	60	12	7	7	NUM
bjos-8661512	60	13	days	day	NOUN
bjos-8661512	60	14	of	of	ADP
bjos-8661512	60	15	cell	cell	NOUN
bjos-8661512	60	16	culture	culture	NOUN
bjos-8661512	60	17	.	.	PUNCT
bjos-8661512	61	1	half	half	NOUN
bjos-8661512	61	2	of	of	ADP
bjos-8661512	61	3	the	the	DET
bjos-8661512	61	4	culture	culture	NOUN
bjos-8661512	61	5	medium	medium	NOUN
bjos-8661512	61	6	and	and	CCONJ
bjos-8661512	61	7	stimuli	stimulus	NOUN
bjos-8661512	61	8	were	be	AUX
bjos-8661512	61	9	changed	change	VERB
bjos-8661512	61	10	every	every	DET
bjos-8661512	61	11	3	3	NUM
bjos-8661512	61	12	days	day	NOUN
bjos-8661512	61	13	.	.	PUNCT
bjos-8661512	62	1	after	after	ADP
bjos-8661512	62	2	7	7	NUM
bjos-8661512	62	3	days	day	NOUN
bjos-8661512	62	4	,	,	PUNCT
bjos-8661512	62	5	trap	trap	NOUN
bjos-8661512	62	6	staining	stain	VERB
bjos-8661512	62	7	was	be	AUX
bjos-8661512	62	8	performed	perform	VERB
bjos-8661512	62	9	,	,	PUNCT
bjos-8661512	62	10	and	and	CCONJ
bjos-8661512	62	11	the	the	DET
bjos-8661512	62	12	number	number	NOUN
bjos-8661512	62	13	of	of	ADP
bjos-8661512	62	14	differentiated	differentiated	ADJ
bjos-8661512	62	15	osteoclast	osteoclast	ADJ
bjos-8661512	62	16	-	-	PUNCT
bjos-8661512	62	17	like	like	ADJ
bjos-8661512	62	18	cells	cell	NOUN
bjos-8661512	62	19	was	be	AUX
bjos-8661512	62	20	determined	determine	VERB
bjos-8661512	62	21	.	.	PUNCT
bjos-8661512	63	1	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	63	2	analyses	analyse	VERB
bjos-8661512	63	3	peptides	peptide	NOUN
bjos-8661512	63	4	,	,	PUNCT
bjos-8661512	63	5	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	63	6	,	,	PUNCT
bjos-8661512	63	7	and	and	CCONJ
bjos-8661512	63	8	doxycycline	doxycycline	NOUN
bjos-8661512	63	9	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	63	10	were	be	AUX
bjos-8661512	63	11	analyzed	analyze	VERB
bjos-8661512	63	12	by	by	ADP
bjos-8661512	63	13	mtt	mtt	NOUN
bjos-8661512	63	14	colorimetric	colorimetric	ADJ
bjos-8661512	63	15	assay	assay	NOUN
bjos-8661512	63	16	(	(	PUNCT
bjos-8661512	63	17	sigma	sigma	PROPN
bjos-8661512	63	18	-	-	PUNCT
bjos-8661512	63	19	aldrich	aldrich	PROPN
bjos-8661512	63	20	,	,	PUNCT
bjos-8661512	63	21	st	st	PROPN
bjos-8661512	63	22	.	.	PROPN
bjos-8661512	63	23	louis	louis	PROPN
bjos-8661512	63	24	,	,	PUNCT
bjos-8661512	63	25	usa	usa	PROPN
bjos-8661512	63	26	)	)	PUNCT
bjos-8661512	63	27	,	,	PUNCT
bjos-8661512	63	28	read	read	VERB
bjos-8661512	63	29	in	in	ADP
bjos-8661512	63	30	a	a	DET
bjos-8661512	63	31	microplate	microplate	NOUN
bjos-8661512	63	32	reader	reader	NOUN
bjos-8661512	63	33	(	(	PUNCT
bjos-8661512	63	34	bio	bio	NOUN
bjos-8661512	63	35	-	-	PUNCT
bjos-8661512	63	36	tek	tek	PROPN
bjos-8661512	63	37	power	power	PROPN
bjos-8661512	63	38	wave	wave	PROPN
bjos-8661512	63	39	ht	ht	PROPN
bjos-8661512	63	40	,	,	PUNCT
bjos-8661512	63	41	usa	usa	PROPN
bjos-8661512	63	42	)	)	PUNCT
bjos-8661512	63	43	at	at	ADP
bjos-8661512	63	44	570	570	NUM
bjos-8661512	63	45	nm17	nm17	PROPN
bjos-8661512	63	46	.	.	PUNCT
bjos-8661512	63	47	cell	cell	NOUN
bjos-8661512	63	48	viability	viability	NOUN
bjos-8661512	63	49	was	be	AUX
bjos-8661512	63	50	determined	determine	VERB
bjos-8661512	63	51	after	after	ADP
bjos-8661512	63	52	3	3	NUM
bjos-8661512	63	53	and	and	CCONJ
bjos-8661512	63	54	7	7	NUM
bjos-8661512	63	55	days	day	NOUN
bjos-8661512	63	56	of	of	ADP
bjos-8661512	63	57	cul4	cul4	NOUN
bjos-8661512	64	1	amorim	amorim	PROPN
bjos-8661512	64	2	et	et	PROPN
bjos-8661512	64	3	al	al	PROPN
bjos-8661512	64	4	.	.	PROPN
bjos-8661512	64	5	ture	ture	PROPN
bjos-8661512	64	6	.	.	PUNCT
bjos-8661512	65	1	all	all	DET
bjos-8661512	65	2	samples	sample	NOUN
bjos-8661512	65	3	were	be	AUX
bjos-8661512	65	4	compared	compare	VERB
bjos-8661512	65	5	to	to	ADP
bjos-8661512	65	6	a	a	DET
bjos-8661512	65	7	positive	positive	ADJ
bjos-8661512	65	8	control	control	NOUN
bjos-8661512	65	9	group	group	NOUN
bjos-8661512	65	10	(	(	PUNCT
bjos-8661512	65	11	raw	raw	ADJ
bjos-8661512	65	12	culture	culture	NOUN
bjos-8661512	65	13	)	)	PUNCT
bjos-8661512	65	14	,	,	PUNCT
bjos-8661512	65	15	considered	consider	VERB
bjos-8661512	65	16	as	as	ADP
bjos-8661512	65	17	100	100	NUM
bjos-8661512	65	18	%	%	NOUN
bjos-8661512	65	19	cell	cell	NOUN
bjos-8661512	65	20	viability	viability	NOUN
bjos-8661512	65	21	.	.	PUNCT
bjos-8661512	66	1	nitric	nitric	ADJ
bjos-8661512	66	2	oxide	oxide	NOUN
bjos-8661512	66	3	production	production	NOUN
bjos-8661512	66	4	analysis	analysis	NOUN
bjos-8661512	66	5	nitrite	nitrite	NOUN
bjos-8661512	66	6	production	production	NOUN
bjos-8661512	66	7	was	be	AUX
bjos-8661512	66	8	evaluated	evaluate	VERB
bjos-8661512	66	9	in	in	ADP
bjos-8661512	66	10	supernatants	supernatant	NOUN
bjos-8661512	66	11	of	of	ADP
bjos-8661512	66	12	cell	cell	NOUN
bjos-8661512	66	13	cultures	culture	NOUN
bjos-8661512	66	14	by	by	ADP
bjos-8661512	66	15	griess	griess	NOUN
bjos-8661512	66	16	reaction	reaction	NOUN
bjos-8661512	66	17	,	,	PUNCT
bjos-8661512	66	18	with	with	ADP
bjos-8661512	66	19	adaptations18	adaptations18	NOUN
bjos-8661512	66	20	.	.	PUNCT
bjos-8661512	67	1	briefly	briefly	ADV
bjos-8661512	67	2	,	,	PUNCT
bjos-8661512	67	3	100	100	NUM
bjos-8661512	67	4	μl	μl	ADP
bjos-8661512	67	5	of	of	ADP
bjos-8661512	67	6	cell	cell	NOUN
bjos-8661512	67	7	culture	culture	NOUN
bjos-8661512	67	8	supernatant	supernatant	NOUN
bjos-8661512	67	9	was	be	AUX
bjos-8661512	67	10	transferred	transfer	VERB
bjos-8661512	67	11	to	to	ADP
bjos-8661512	67	12	a	a	DET
bjos-8661512	67	13	new	new	ADJ
bjos-8661512	67	14	96	96	NUM
bjos-8661512	67	15	-	-	PUNCT
bjos-8661512	67	16	well	well	NOUN
bjos-8661512	67	17	plate	plate	NOUN
bjos-8661512	67	18	(	(	PUNCT
bjos-8661512	67	19	kasvi	kasvi	PROPN
bjos-8661512	67	20	,	,	PUNCT
bjos-8661512	67	21	china	china	PROPN
bjos-8661512	67	22	)	)	PUNCT
bjos-8661512	67	23	.	.	PUNCT
bjos-8661512	68	1	then	then	ADV
bjos-8661512	68	2	,	,	PUNCT
bjos-8661512	68	3	100	100	NUM
bjos-8661512	68	4	μl	μl	ADP
bjos-8661512	68	5	of	of	ADP
bjos-8661512	68	6	1	1	NUM
bjos-8661512	68	7	%	%	NOUN
bjos-8661512	68	8	sulfanilamide	sulfanilamide	NOUN
bjos-8661512	68	9	phosphoric	phosphoric	NOUN
bjos-8661512	68	10	acid	acid	NOUN
bjos-8661512	68	11	solution	solution	NOUN
bjos-8661512	68	12	and	and	CCONJ
bjos-8661512	68	13	2.5	2.5	NUM
bjos-8661512	68	14	%	%	NOUN
bjos-8661512	68	15	of	of	ADP
bjos-8661512	68	16	1	1	NUM
bjos-8661512	68	17	%	%	NOUN
bjos-8661512	68	18	naphthyl	naphthyl	PROPN
bjos-8661512	68	19	ethylenediamine	ethylenediamine	PROPN
bjos-8661512	68	20	phosphoric	phosphoric	NOUN
bjos-8661512	68	21	acid	acid	NOUN
bjos-8661512	68	22	(	(	PUNCT
bjos-8661512	68	23	1:1	1:1	NUM
bjos-8661512	68	24	)	)	PUNCT
bjos-8661512	68	25	was	be	AUX
bjos-8661512	68	26	added	add	VERB
bjos-8661512	68	27	.	.	PUNCT
bjos-8661512	69	1	after	after	ADP
bjos-8661512	69	2	10	10	NUM
bjos-8661512	69	3	min	min	NOUN
bjos-8661512	69	4	,	,	PUNCT
bjos-8661512	69	5	reading	reading	NOUN
bjos-8661512	69	6	was	be	AUX
bjos-8661512	69	7	performed	perform	VERB
bjos-8661512	69	8	in	in	ADP
bjos-8661512	69	9	a	a	DET
bjos-8661512	69	10	microplate	microplate	NOUN
bjos-8661512	69	11	reader	reader	NOUN
bjos-8661512	69	12	(	(	PUNCT
bjos-8661512	69	13	bio	bio	NOUN
bjos-8661512	69	14	-	-	PUNCT
bjos-8661512	69	15	tek	tek	PROPN
bjos-8661512	69	16	powerwave	powerwave	PROPN
bjos-8661512	69	17	ht	ht	PROPN
bjos-8661512	69	18	,	,	PUNCT
bjos-8661512	69	19	usa	usa	PROPN
bjos-8661512	69	20	)	)	PUNCT
bjos-8661512	69	21	at	at	ADP
bjos-8661512	69	22	490	490	NUM
bjos-8661512	69	23	nm	nm	NOUN
bjos-8661512	69	24	.	.	PUNCT
bjos-8661512	70	1	the	the	DET
bjos-8661512	70	2	amount	amount	NOUN
bjos-8661512	70	3	of	of	ADP
bjos-8661512	70	4	nitrite	nitrite	NOUN
bjos-8661512	70	5	was	be	AUX
bjos-8661512	70	6	calculated	calculate	VERB
bjos-8661512	70	7	based	base	VERB
bjos-8661512	70	8	on	on	ADP
bjos-8661512	70	9	a	a	DET
bjos-8661512	70	10	standard	standard	ADJ
bjos-8661512	70	11	curve	curve	NOUN
bjos-8661512	70	12	of	of	ADP
bjos-8661512	70	13	sodium	sodium	NOUN
bjos-8661512	70	14	nitrite	nitrite	NOUN
bjos-8661512	70	15	(	(	PUNCT
bjos-8661512	70	16	1.5625	1.5625	NUM
bjos-8661512	70	17	µm	µm	ADP
bjos-8661512	70	18	to	to	ADP
bjos-8661512	70	19	200	200	NUM
bjos-8661512	70	20	µm)18	µm)18	NOUN
bjos-8661512	70	21	.	.	PUNCT
bjos-8661512	71	1	tartrate	tartrate	NOUN
bjos-8661512	71	2	-	-	PUNCT
bjos-8661512	71	3	resistant	resistant	ADJ
bjos-8661512	71	4	acid	acid	NOUN
bjos-8661512	71	5	phosphatase	phosphatase	NOUN
bjos-8661512	71	6	(	(	PUNCT
bjos-8661512	71	7	trap	trap	NOUN
bjos-8661512	71	8	)	)	PUNCT
bjos-8661512	71	9	staining	stain	VERB
bjos-8661512	71	10	trap	trap	NOUN
bjos-8661512	71	11	staining	stain	VERB
bjos-8661512	71	12	was	be	AUX
bjos-8661512	71	13	performed	perform	VERB
bjos-8661512	71	14	after	after	ADP
bjos-8661512	71	15	7	7	NUM
bjos-8661512	71	16	days	day	NOUN
bjos-8661512	71	17	of	of	ADP
bjos-8661512	71	18	incubation	incubation	NOUN
bjos-8661512	71	19	for	for	ADP
bjos-8661512	71	20	the	the	DET
bjos-8661512	71	21	quantification	quantification	NOUN
bjos-8661512	71	22	of	of	ADP
bjos-8661512	71	23	differentiated	differentiated	ADJ
bjos-8661512	71	24	osteoclast	osteoclast	ADJ
bjos-8661512	71	25	-	-	PUNCT
bjos-8661512	71	26	like	like	ADJ
bjos-8661512	71	27	cells	cell	NOUN
bjos-8661512	71	28	.	.	PUNCT
bjos-8661512	72	1	the	the	DET
bjos-8661512	72	2	tartrate	tartrate	NOUN
bjos-8661512	72	3	-	-	PUNCT
bjos-8661512	72	4	resistant	resistant	ADJ
bjos-8661512	72	5	acid	acid	NOUN
bjos-8661512	72	6	phosphatase	phosphatase	NOUN
bjos-8661512	72	7	(	(	PUNCT
bjos-8661512	72	8	trap	trap	NOUN
bjos-8661512	72	9	)	)	PUNCT
bjos-8661512	72	10	kit	kit	NOUN
bjos-8661512	72	11	(	(	PUNCT
bjos-8661512	72	12	sigma	sigma	PROPN
bjos-8661512	72	13	-	-	PUNCT
bjos-8661512	72	14	aldrich	aldrich	PROPN
bjos-8661512	72	15	,	,	PUNCT
bjos-8661512	72	16	st	st	PROPN
bjos-8661512	72	17	.	.	PROPN
bjos-8661512	72	18	louis	louis	PROPN
bjos-8661512	72	19	,	,	PUNCT
bjos-8661512	72	20	usa	usa	PROPN
bjos-8661512	72	21	)	)	PUNCT
bjos-8661512	72	22	was	be	AUX
bjos-8661512	72	23	used	use	VERB
bjos-8661512	72	24	according	accord	VERB
bjos-8661512	72	25	to	to	ADP
bjos-8661512	72	26	the	the	DET
bjos-8661512	72	27	manufacturer	manufacturer	NOUN
bjos-8661512	72	28	’s	’s	PART
bjos-8661512	72	29	specifications	specification	NOUN
bjos-8661512	72	30	.	.	PUNCT
bjos-8661512	73	1	osteoclast	osteoclast	ADJ
bjos-8661512	73	2	-	-	PUNCT
bjos-8661512	73	3	like	like	ADJ
bjos-8661512	73	4	cells	cell	NOUN
bjos-8661512	73	5	were	be	AUX
bjos-8661512	73	6	considered	consider	VERB
bjos-8661512	73	7	as	as	ADP
bjos-8661512	73	8	trap	trap	NOUN
bjos-8661512	73	9	-	-	PUNCT
bjos-8661512	73	10	positive	positive	ADJ
bjos-8661512	73	11	cells	cell	NOUN
bjos-8661512	73	12	(	(	PUNCT
bjos-8661512	73	13	with	with	ADP
bjos-8661512	73	14	red	red	ADJ
bjos-8661512	73	15	/	/	SYM
bjos-8661512	73	16	orange	orange	NOUN
bjos-8661512	73	17	trap	trap	NOUN
bjos-8661512	73	18	staining	staining	NOUN
bjos-8661512	73	19	)	)	PUNCT
bjos-8661512	73	20	with	with	ADP
bjos-8661512	73	21	more	more	ADJ
bjos-8661512	73	22	than	than	ADP
bjos-8661512	73	23	three	three	NUM
bjos-8661512	73	24	nuclei	nucleus	NOUN
bjos-8661512	73	25	.	.	PUNCT
bjos-8661512	74	1	statistical	statistical	ADJ
bjos-8661512	74	2	analysis	analysis	NOUN
bjos-8661512	74	3	data	datum	NOUN
bjos-8661512	74	4	obtained	obtain	VERB
bjos-8661512	74	5	was	be	AUX
bjos-8661512	74	6	analyzed	analyze	VERB
bjos-8661512	74	7	by	by	ADP
bjos-8661512	74	8	the	the	DET
bjos-8661512	74	9	standard	standard	ADJ
bjos-8661512	74	10	error	error	NOUN
bjos-8661512	74	11	of	of	ADP
bjos-8661512	74	12	the	the	DET
bjos-8661512	74	13	mean	mean	NOUN
bjos-8661512	74	14	for	for	ADP
bjos-8661512	74	15	each	each	DET
bjos-8661512	74	16	experiment	experiment	NOUN
bjos-8661512	74	17	.	.	PUNCT
bjos-8661512	75	1	the	the	DET
bjos-8661512	75	2	normality	normality	NOUN
bjos-8661512	75	3	was	be	AUX
bjos-8661512	75	4	evaluated	evaluate	VERB
bjos-8661512	75	5	(	(	PUNCT
bjos-8661512	75	6	kolmogorov	kolmogorov	ADJ
bjos-8661512	75	7	-	-	PUNCT
bjos-8661512	75	8	smirnov	smirnov	ADJ
bjos-8661512	75	9	test	test	NOUN
bjos-8661512	75	10	)	)	PUNCT
bjos-8661512	75	11	,	,	PUNCT
bjos-8661512	75	12	and	and	CCONJ
bjos-8661512	75	13	subsequent	subsequent	ADJ
bjos-8661512	75	14	parametric	parametric	ADJ
bjos-8661512	75	15	statistical	statistical	ADJ
bjos-8661512	75	16	analysis	analysis	NOUN
bjos-8661512	75	17	was	be	AUX
bjos-8661512	75	18	carried	carry	VERB
bjos-8661512	75	19	out	out	ADP
bjos-8661512	75	20	by	by	ADP
bjos-8661512	75	21	two	two	NUM
bjos-8661512	75	22	-	-	PUNCT
bjos-8661512	75	23	way	way	NOUN
bjos-8661512	75	24	analysis	analysis	NOUN
bjos-8661512	75	25	of	of	ADP
bjos-8661512	75	26	variance	variance	NOUN
bjos-8661512	75	27	(	(	PUNCT
bjos-8661512	75	28	two	two	NUM
bjos-8661512	75	29	-	-	PUNCT
bjos-8661512	75	30	way	way	NOUN
bjos-8661512	75	31	anova	anova	PROPN
bjos-8661512	75	32	)	)	PUNCT
bjos-8661512	75	33	for	for	ADP
bjos-8661512	75	34	the	the	DET
bjos-8661512	75	35	data	datum	NOUN
bjos-8661512	75	36	from	from	ADP
bjos-8661512	75	37	mtt	mtt	NOUN
bjos-8661512	75	38	and	and	CCONJ
bjos-8661512	75	39	no	no	DET
bjos-8661512	75	40	production	production	NOUN
bjos-8661512	75	41	and	and	CCONJ
bjos-8661512	75	42	one	one	NUM
bjos-8661512	75	43	-	-	PUNCT
bjos-8661512	75	44	way	way	NOUN
bjos-8661512	75	45	anova	anova	X
bjos-8661512	75	46	for	for	ADP
bjos-8661512	75	47	trap	trap	NOUN
bjos-8661512	75	48	analyses	analysis	NOUN
bjos-8661512	75	49	.	.	PUNCT
bjos-8661512	76	1	tukey	tukey	PROPN
bjos-8661512	76	2	’s	’s	PART
bjos-8661512	76	3	posthoc	posthoc	PROPN
bjos-8661512	76	4	test	test	NOUN
bjos-8661512	76	5	was	be	AUX
bjos-8661512	76	6	applied	apply	VERB
bjos-8661512	76	7	to	to	PART
bjos-8661512	76	8	identify	identify	VERB
bjos-8661512	76	9	statistical	statistical	ADJ
bjos-8661512	76	10	differences	difference	NOUN
bjos-8661512	76	11	.	.	PUNCT
bjos-8661512	77	1	analyses	analysis	NOUN
bjos-8661512	77	2	were	be	AUX
bjos-8661512	77	3	considered	consider	VERB
bjos-8661512	77	4	at	at	ADP
bjos-8661512	77	5	the	the	DET
bjos-8661512	77	6	95	95	NUM
bjos-8661512	77	7	%	%	NOUN
bjos-8661512	77	8	significance	significance	NOUN
bjos-8661512	77	9	level	level	NOUN
bjos-8661512	77	10	,	,	PUNCT
bjos-8661512	77	11	and	and	CCONJ
bjos-8661512	77	12	statistical	statistical	ADJ
bjos-8661512	77	13	differences	difference	NOUN
bjos-8661512	77	14	were	be	AUX
bjos-8661512	77	15	considered	consider	VERB
bjos-8661512	77	16	when	when	SCONJ
bjos-8661512	77	17	p<0.05	p<0.05	NOUN
bjos-8661512	77	18	.	.	PUNCT
bjos-8661512	78	1	statistical	statistical	ADJ
bjos-8661512	78	2	analysis	analysis	NOUN
bjos-8661512	78	3	was	be	AUX
bjos-8661512	78	4	performed	perform	VERB
bjos-8661512	78	5	using	use	VERB
bjos-8661512	78	6	graphpad	graphpad	NOUN
bjos-8661512	78	7	prism	prism	NOUN
bjos-8661512	78	8	6.0	6.0	NUM
bjos-8661512	78	9	software	software	NOUN
bjos-8661512	78	10	(	(	PUNCT
bjos-8661512	78	11	instat	instat	PROPN
bjos-8661512	78	12	california	california	PROPN
bjos-8661512	78	13	,	,	PUNCT
bjos-8661512	78	14	usa	usa	PROPN
bjos-8661512	78	15	)	)	PUNCT
bjos-8661512	78	16	.	.	PUNCT
bjos-8661512	79	1	results	result	VERB
bjos-8661512	79	2	hdp	hdp	NOUN
bjos-8661512	79	3	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	79	4	the	the	DET
bjos-8661512	79	5	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	79	6	of	of	ADP
bjos-8661512	79	7	substances	substance	NOUN
bjos-8661512	79	8	was	be	AUX
bjos-8661512	79	9	determined	determine	VERB
bjos-8661512	79	10	by	by	ADP
bjos-8661512	79	11	cell	cell	NOUN
bjos-8661512	79	12	viability	viability	NOUN
bjos-8661512	79	13	assays	assay	NOUN
bjos-8661512	79	14	after	after	ADP
bjos-8661512	79	15	3	3	NUM
bjos-8661512	79	16	and	and	CCONJ
bjos-8661512	79	17	7	7	NUM
bjos-8661512	79	18	days	day	NOUN
bjos-8661512	79	19	of	of	ADP
bjos-8661512	79	20	cell	cell	NOUN
bjos-8661512	79	21	culture	culture	NOUN
bjos-8661512	79	22	in	in	ADP
bjos-8661512	79	23	the	the	DET
bjos-8661512	79	24	presence	presence	NOUN
bjos-8661512	79	25	of	of	ADP
bjos-8661512	79	26	hdps	hdps	PROPN
bjos-8661512	79	27	clavanin	clavanin	PROPN
bjos-8661512	79	28	a	a	PRON
bjos-8661512	79	29	,	,	PUNCT
bjos-8661512	79	30	clavanin	clavanin	PROPN
bjos-8661512	79	31	mo	mo	PROPN
bjos-8661512	79	32	,	,	PUNCT
bjos-8661512	79	33	ll-37	ll-37	PROPN
bjos-8661512	79	34	,	,	PUNCT
bjos-8661512	79	35	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	79	36	and	and	CCONJ
bjos-8661512	79	37	doxycycline	doxycycline	NOUN
bjos-8661512	79	38	.	.	PUNCT
bjos-8661512	80	1	hdps	hdps	PROPN
bjos-8661512	80	2	and	and	CCONJ
bjos-8661512	80	3	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	80	4	were	be	AUX
bjos-8661512	80	5	not	not	PART
bjos-8661512	80	6	cytotoxic	cytotoxic	ADJ
bjos-8661512	80	7	to	to	PART
bjos-8661512	80	8	pre	pre	VERB
bjos-8661512	80	9	-	-	NOUN
bjos-8661512	80	10	osteoclasts	osteoclasts	ADJ
bjos-8661512	80	11	(	(	PUNCT
bjos-8661512	80	12	data	datum	NOUN
bjos-8661512	80	13	not	not	PART
bjos-8661512	80	14	shown	show	VERB
bjos-8661512	80	15	)	)	PUNCT
bjos-8661512	80	16	.	.	PUNCT
bjos-8661512	81	1	however	however	ADV
bjos-8661512	81	2	,	,	PUNCT
bjos-8661512	81	3	doxycycline	doxycycline	NOUN
bjos-8661512	81	4	,	,	PUNCT
bjos-8661512	81	5	at	at	ADP
bjos-8661512	81	6	the	the	DET
bjos-8661512	81	7	high	high	ADJ
bjos-8661512	81	8	concentration	concentration	NOUN
bjos-8661512	81	9	(	(	PUNCT
bjos-8661512	81	10	128	128	NUM
bjos-8661512	81	11	μg.ml1	μg.ml1	NUM
bjos-8661512	81	12	)	)	PUNCT
bjos-8661512	81	13	reduced	reduce	VERB
bjos-8661512	81	14	cell	cell	NOUN
bjos-8661512	81	15	viability	viability	NOUN
bjos-8661512	81	16	by	by	ADP
bjos-8661512	81	17	48	48	NUM
bjos-8661512	81	18	%	%	NOUN
bjos-8661512	81	19	(	(	PUNCT
bjos-8661512	81	20	p<0.05	p<0.05	NOUN
bjos-8661512	81	21	)	)	PUNCT
bjos-8661512	81	22	,	,	PUNCT
bjos-8661512	81	23	after	after	ADP
bjos-8661512	81	24	3	3	NUM
bjos-8661512	81	25	days	day	NOUN
bjos-8661512	81	26	of	of	ADP
bjos-8661512	81	27	incubation	incubation	NOUN
bjos-8661512	81	28	,	,	PUNCT
bjos-8661512	81	29	compared	compare	VERB
bjos-8661512	81	30	to	to	ADP
bjos-8661512	81	31	the	the	DET
bjos-8661512	81	32	control	control	NOUN
bjos-8661512	81	33	group	group	NOUN
bjos-8661512	81	34	(	(	PUNCT
bjos-8661512	81	35	data	datum	NOUN
bjos-8661512	81	36	not	not	PART
bjos-8661512	81	37	shown	show	VERB
bjos-8661512	81	38	)	)	PUNCT
bjos-8661512	81	39	.	.	PUNCT
bjos-8661512	82	1	similar	similar	ADJ
bjos-8661512	82	2	viability	viability	NOUN
bjos-8661512	82	3	results	result	NOUN
bjos-8661512	82	4	were	be	AUX
bjos-8661512	82	5	observed	observe	VERB
bjos-8661512	82	6	in	in	ADP
bjos-8661512	82	7	osteoclast	osteoclast	ADJ
bjos-8661512	82	8	-	-	PUNCT
bjos-8661512	82	9	like	like	ADJ
bjos-8661512	82	10	cells	cell	NOUN
bjos-8661512	82	11	(	(	PUNCT
bjos-8661512	82	12	raw	raw	ADJ
bjos-8661512	82	13	cells	cell	NOUN
bjos-8661512	82	14	with	with	ADP
bjos-8661512	82	15	rrankl	rrankl	NOUN
bjos-8661512	82	16	)	)	PUNCT
bjos-8661512	82	17	,	,	PUNCT
bjos-8661512	82	18	and	and	CCONJ
bjos-8661512	82	19	substances	substance	NOUN
bjos-8661512	82	20	after	after	ADP
bjos-8661512	82	21	3	3	NUM
bjos-8661512	82	22	and	and	CCONJ
bjos-8661512	82	23	7	7	NUM
bjos-8661512	82	24	days	day	NOUN
bjos-8661512	82	25	incubation	incubation	NOUN
bjos-8661512	82	26	.	.	PUNCT
bjos-8661512	83	1	hdps	hdps	PROPN
bjos-8661512	83	2	,	,	PUNCT
bjos-8661512	83	3	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	83	4	and	and	CCONJ
bjos-8661512	83	5	doxycycline	doxycycline	NOUN
bjos-8661512	83	6	were	be	AUX
bjos-8661512	83	7	not	not	PART
bjos-8661512	83	8	cytotoxic	cytotoxic	ADJ
bjos-8661512	83	9	to	to	PART
bjos-8661512	83	10	rrankl	rrankl	VERB
bjos-8661512	83	11	-	-	PUNCT
bjos-8661512	83	12	stimulated	stimulate	VERB
bjos-8661512	83	13	cells	cell	NOUN
bjos-8661512	83	14	(	(	PUNCT
bjos-8661512	83	15	figure	figure	NOUN
bjos-8661512	83	16	1	1	NUM
bjos-8661512	83	17	)	)	PUNCT
bjos-8661512	83	18	.	.	PUNCT
bjos-8661512	84	1	however	however	ADV
bjos-8661512	84	2	,	,	PUNCT
bjos-8661512	84	3	128	128	NUM
bjos-8661512	84	4	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	84	5	of	of	ADP
bjos-8661512	84	6	doxycycline	doxycycline	NOUN
bjos-8661512	84	7	reduced	reduce	VERB
bjos-8661512	84	8	cell	cell	NOUN
bjos-8661512	84	9	viability	viability	NOUN
bjos-8661512	84	10	by	by	ADP
bjos-8661512	84	11	42	42	NUM
bjos-8661512	84	12	%	%	NOUN
bjos-8661512	84	13	after	after	ADP
bjos-8661512	84	14	3	3	NUM
bjos-8661512	84	15	days	day	NOUN
bjos-8661512	84	16	,	,	PUNCT
bjos-8661512	84	17	compared	compare	VERB
bjos-8661512	84	18	to	to	ADP
bjos-8661512	84	19	the	the	DET
bjos-8661512	84	20	control	control	NOUN
bjos-8661512	84	21	group	group	NOUN
bjos-8661512	84	22	(	(	PUNCT
bjos-8661512	84	23	p<0.05	p<0.05	PROPN
bjos-8661512	84	24	)	)	PUNCT
bjos-8661512	84	25	.	.	PUNCT
bjos-8661512	85	1	indeed	indeed	ADV
bjos-8661512	85	2	,	,	PUNCT
bjos-8661512	85	3	hdps	hdps	PROPN
bjos-8661512	85	4	were	be	AUX
bjos-8661512	85	5	not	not	PART
bjos-8661512	85	6	cytotoxic	cytotoxic	ADJ
bjos-8661512	85	7	and	and	CCONJ
bjos-8661512	85	8	only	only	ADV
bjos-8661512	85	9	doxycycline	doxycycline	NOUN
bjos-8661512	85	10	at	at	ADP
bjos-8661512	85	11	128	128	NUM
bjos-8661512	85	12	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	85	13	demonstrated	demonstrate	VERB
bjos-8661512	85	14	a	a	DET
bjos-8661512	85	15	cytotoxic	cytotoxic	ADJ
bjos-8661512	85	16	effect	effect	NOUN
bjos-8661512	85	17	on	on	ADP
bjos-8661512	85	18	osteoclast	osteoclast	ADJ
bjos-8661512	85	19	-	-	PUNCT
bjos-8661512	85	20	like	like	ADJ
bjos-8661512	85	21	cells	cell	NOUN
bjos-8661512	85	22	(	(	PUNCT
bjos-8661512	85	23	rrankl	rrankl	NOUN
bjos-8661512	85	24	-	-	PUNCT
bjos-8661512	85	25	stimulated	stimulate	VERB
bjos-8661512	85	26	and	and	CCONJ
bjos-8661512	85	27	raw	raw	ADJ
bjos-8661512	85	28	cells	cell	NOUN
bjos-8661512	85	29	)	)	PUNCT
bjos-8661512	85	30	.	.	PUNCT
bjos-8661512	86	1	5	5	NUM
bjos-8661512	86	2	amorim	amorim	NOUN
bjos-8661512	86	3	et	et	PROPN
bjos-8661512	86	4	al	al	PROPN
bjos-8661512	86	5	.	.	PROPN
bjos-8661512	86	6	nitric	nitric	ADJ
bjos-8661512	86	7	oxide	oxide	NOUN
bjos-8661512	86	8	production	production	NOUN
bjos-8661512	86	9	cell	cell	NOUN
bjos-8661512	86	10	cultures	culture	NOUN
bjos-8661512	86	11	with	with	ADP
bjos-8661512	86	12	hdps	hdps	NOUN
bjos-8661512	86	13	,	,	PUNCT
bjos-8661512	86	14	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	86	15	,	,	PUNCT
bjos-8661512	86	16	and	and	CCONJ
bjos-8661512	86	17	doxycycline	doxycycline	NOUN
bjos-8661512	86	18	produced	produce	VERB
bjos-8661512	86	19	basal	basal	PROPN
bjos-8661512	86	20	levels	level	NOUN
bjos-8661512	86	21	of	of	ADP
bjos-8661512	86	22	no	no	NOUN
bjos-8661512	86	23	,	,	PUNCT
bjos-8661512	86	24	compared	compare	VERB
bjos-8661512	86	25	to	to	ADP
bjos-8661512	86	26	the	the	DET
bjos-8661512	86	27	control	control	NOUN
bjos-8661512	86	28	group	group	NOUN
bjos-8661512	86	29	(	(	PUNCT
bjos-8661512	86	30	data	datum	NOUN
bjos-8661512	86	31	not	not	PART
bjos-8661512	86	32	shown	show	VERB
bjos-8661512	86	33	)	)	PUNCT
bjos-8661512	86	34	.	.	PUNCT
bjos-8661512	87	1	the	the	DET
bjos-8661512	87	2	rrankl	rrankl	NOUN
bjos-8661512	87	3	increased	increase	VERB
bjos-8661512	87	4	no	no	DET
bjos-8661512	87	5	production	production	NOUN
bjos-8661512	87	6	in	in	ADP
bjos-8661512	87	7	figure	figure	NOUN
bjos-8661512	87	8	1	1	NUM
bjos-8661512	87	9	.	.	PUNCT
bjos-8661512	88	1	clavanin	clavanin	PROPN
bjos-8661512	88	2	a	a	PRON
bjos-8661512	88	3	,	,	PUNCT
bjos-8661512	88	4	clavanin	clavanin	PROPN
bjos-8661512	88	5	mo	mo	PROPN
bjos-8661512	88	6	,	,	PUNCT
bjos-8661512	88	7	ll-37	ll-37	PROPN
bjos-8661512	88	8	,	,	PUNCT
bjos-8661512	88	9	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	88	10	and	and	CCONJ
bjos-8661512	88	11	doxycycline	doxycycline	NOUN
bjos-8661512	88	12	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	88	13	at	at	ADP
bjos-8661512	88	14	2	2	NUM
bjos-8661512	88	15	,	,	PUNCT
bjos-8661512	88	16	8	8	NUM
bjos-8661512	88	17	,	,	PUNCT
bjos-8661512	88	18	32	32	NUM
bjos-8661512	88	19	and	and	CCONJ
bjos-8661512	88	20	128	128	NUM
bjos-8661512	88	21	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	88	22	on	on	ADP
bjos-8661512	88	23	2.5x103	2.5x103	ADJ
bjos-8661512	88	24	raw	raw	ADJ
bjos-8661512	88	25	cells	cell	NOUN
bjos-8661512	88	26	,	,	PUNCT
bjos-8661512	88	27	after	after	ADP
bjos-8661512	88	28	3	3	NUM
bjos-8661512	88	29	and	and	CCONJ
bjos-8661512	88	30	7	7	NUM
bjos-8661512	88	31	days	day	NOUN
bjos-8661512	88	32	,	,	PUNCT
bjos-8661512	88	33	by	by	ADP
bjos-8661512	88	34	mtt	mtt	NOUN
bjos-8661512	88	35	assay	assay	NOUN
bjos-8661512	88	36	.	.	PUNCT
bjos-8661512	89	1	cultures	culture	NOUN
bjos-8661512	89	2	were	be	AUX
bjos-8661512	89	3	stimulated	stimulate	VERB
bjos-8661512	89	4	with	with	ADP
bjos-8661512	89	5	100	100	NUM
bjos-8661512	89	6	ng.ml-1	ng.ml-1	NOUN
bjos-8661512	89	7	of	of	ADP
bjos-8661512	89	8	rrankl	rrankl	NOUN
bjos-8661512	89	9	.	.	PUNCT
bjos-8661512	90	1	cell	cell	NOUN
bjos-8661512	90	2	viability	viability	NOUN
bjos-8661512	90	3	was	be	AUX
bjos-8661512	90	4	represented	represent	VERB
bjos-8661512	90	5	by	by	ADP
bjos-8661512	90	6	percentage	percentage	NOUN
bjos-8661512	90	7	.	.	PUNCT
bjos-8661512	91	1	control	control	PROPN
bjos-8661512	91	2	group	group	PROPN
bjos-8661512	91	3	was	be	AUX
bjos-8661512	91	4	represented	represent	VERB
bjos-8661512	91	5	by	by	ADP
bjos-8661512	91	6	2.5x103	2.5x103	ADJ
bjos-8661512	91	7	raw	raw	ADJ
bjos-8661512	91	8	cells	cell	NOUN
bjos-8661512	91	9	stimulated	stimulate	VERB
bjos-8661512	91	10	with	with	ADP
bjos-8661512	91	11	100ng.ml-1	100ng.ml-1	NUM
bjos-8661512	91	12	of	of	ADP
bjos-8661512	91	13	rrankl	rrankl	NOUN
bjos-8661512	91	14	and	and	CCONJ
bjos-8661512	91	15	considered	consider	VERB
bjos-8661512	91	16	100	100	NUM
bjos-8661512	91	17	%	%	NOUN
bjos-8661512	91	18	of	of	ADP
bjos-8661512	91	19	cell	cell	NOUN
bjos-8661512	91	20	viability	viability	NOUN
bjos-8661512	91	21	.	.	PUNCT
bjos-8661512	92	1	all	all	DET
bjos-8661512	92	2	experiments	experiment	NOUN
bjos-8661512	92	3	were	be	AUX
bjos-8661512	92	4	done	do	VERB
bjos-8661512	92	5	in	in	ADP
bjos-8661512	92	6	technical	technical	ADJ
bjos-8661512	92	7	and	and	CCONJ
bjos-8661512	92	8	biological	biological	ADJ
bjos-8661512	92	9	triplicates	triplicate	NOUN
bjos-8661512	92	10	.	.	PUNCT
bjos-8661512	93	1	statistical	statistical	ADJ
bjos-8661512	93	2	differences	difference	NOUN
bjos-8661512	93	3	by	by	ADP
bjos-8661512	93	4	two	two	NUM
bjos-8661512	93	5	-	-	PUNCT
bjos-8661512	93	6	way	way	NOUN
bjos-8661512	93	7	anova	anova	PROPN
bjos-8661512	93	8	test	test	NOUN
bjos-8661512	93	9	and	and	CCONJ
bjos-8661512	93	10	tukey	tukey	PROPN
bjos-8661512	93	11	’s	’s	PART
bjos-8661512	93	12	post	post	X
bjos-8661512	93	13	hoc	hoc	X
bjos-8661512	93	14	were	be	AUX
bjos-8661512	93	15	represented	represent	VERB
bjos-8661512	93	16	by	by	ADP
bjos-8661512	93	17	*	*	PROPN
bjos-8661512	93	18	p<0.05	p<0.05	PROPN
bjos-8661512	93	19	,	,	PUNCT
bjos-8661512	93	20	*	*	PUNCT
bjos-8661512	93	21	*	*	X
bjos-8661512	93	22	p<0.005	p<0.005	ADP
bjos-8661512	93	23	,	,	PUNCT
bjos-8661512	93	24	*	*	PUNCT
bjos-8661512	93	25	*	*	PUNCT
bjos-8661512	93	26	*	*	NOUN
bjos-8661512	93	27	p<0.0005	p<0.0005	NOUN
bjos-8661512	93	28	and	and	CCONJ
bjos-8661512	93	29	*	*	NOUN
bjos-8661512	93	30	*	*	PUNCT
bjos-8661512	93	31	*	*	PUNCT
bjos-8661512	93	32	*	*	PUNCT
bjos-8661512	93	33	p<0.0001	p<0.0001	VERB
bjos-8661512	93	34	compared	compare	VERB
bjos-8661512	93	35	to	to	ADP
bjos-8661512	93	36	each	each	DET
bjos-8661512	93	37	concentration	concentration	NOUN
bjos-8661512	93	38	and	and	CCONJ
bjos-8661512	93	39	time	time	NOUN
bjos-8661512	93	40	tested	test	VERB
bjos-8661512	93	41	conditions	condition	NOUN
bjos-8661512	93	42	;	;	PUNCT
bjos-8661512	93	43	dark	dark	ADJ
bjos-8661512	93	44	green	green	ADJ
bjos-8661512	93	45	bars	bar	NOUN
bjos-8661512	93	46	represent	represent	VERB
bjos-8661512	93	47	statistical	statistical	ADJ
bjos-8661512	93	48	differences	difference	NOUN
bjos-8661512	93	49	observed	observe	VERB
bjos-8661512	93	50	on	on	ADP
bjos-8661512	93	51	day	day	NOUN
bjos-8661512	93	52	3	3	NUM
bjos-8661512	93	53	;	;	PUNCT
bjos-8661512	93	54	light	light	ADJ
bjos-8661512	93	55	green	green	ADJ
bjos-8661512	93	56	bars	bar	NOUN
bjos-8661512	93	57	represent	represent	VERB
bjos-8661512	93	58	statistical	statistical	ADJ
bjos-8661512	93	59	differences	difference	NOUN
bjos-8661512	93	60	observed	observe	VERB
bjos-8661512	93	61	on	on	ADP
bjos-8661512	93	62	day	day	NOUN
bjos-8661512	93	63	7	7	NUM
bjos-8661512	93	64	.	.	PUNCT
bjos-8661512	94	1	ce	ce	PROPN
bjos-8661512	94	2	ll	ll	PROPN
bjos-8661512	94	3	vi	vi	PROPN
bjos-8661512	94	4	ab	ab	PROPN
bjos-8661512	94	5	ili	ili	PROPN
bjos-8661512	95	1	ty	ty	INTJ
bjos-8661512	95	2	(	(	PUNCT
bjos-8661512	95	3	%	%	NOUN
bjos-8661512	95	4	)	)	PUNCT
bjos-8661512	95	5	clavanin	clavanin	NOUN
bjos-8661512	95	6	a	a	DET
bjos-8661512	95	7	*	*	PUNCT
bjos-8661512	95	8	*	*	SYM
bjos-8661512	95	9	250	250	NUM
bjos-8661512	95	10	200	200	NUM
bjos-8661512	95	11	150	150	NUM
bjos-8661512	95	12	100	100	NUM
bjos-8661512	95	13	50	50	NUM
bjos-8661512	95	14	0	0	NUM
bjos-8661512	95	15	contro	contro	PROPN
bjos-8661512	95	16	l	l	PROPN
bjos-8661512	95	17	2	2	NUM
bjos-8661512	95	18	μg.m	μg.m	NOUN
bjos-8661512	95	19	l1	l1	PROPN
bjos-8661512	95	20	8	8	NUM
bjos-8661512	95	21	μg.m	μg.m	PROPN
bjos-8661512	95	22	l1	l1	PROPN
bjos-8661512	95	23	32	32	NUM
bjos-8661512	95	24	μg.m	μg.m	PROPN
bjos-8661512	95	25	l1	l1	PROPN
bjos-8661512	95	26	128	128	NUM
bjos-8661512	95	27	μg.m	μg.m	PROPN
bjos-8661512	95	28	l1	l1	PROPN
bjos-8661512	95	29	ce	ce	PROPN
bjos-8661512	95	30	ll	ll	PROPN
bjos-8661512	95	31	vi	vi	PROPN
bjos-8661512	95	32	ab	ab	PROPN
bjos-8661512	95	33	ili	ili	PROPN
bjos-8661512	96	1	ty	ty	INTJ
bjos-8661512	96	2	(	(	PUNCT
bjos-8661512	96	3	%	%	NOUN
bjos-8661512	96	4	)	)	PUNCT
bjos-8661512	96	5	clavanin	clavanin	PROPN
bjos-8661512	96	6	mo	mo	PROPN
bjos-8661512	96	7	*	*	PUNCT
bjos-8661512	96	8	*	*	PUNCT
bjos-8661512	97	1	*	*	PUNCT
bjos-8661512	97	2	*	*	PUNCT
bjos-8661512	97	3	*	*	PUNCT
bjos-8661512	97	4	*	*	PUNCT
bjos-8661512	97	5	250	250	NUM
bjos-8661512	97	6	200	200	NUM
bjos-8661512	97	7	150	150	NUM
bjos-8661512	97	8	100	100	NUM
bjos-8661512	97	9	50	50	NUM
bjos-8661512	97	10	0	0	NUM
bjos-8661512	97	11	contro	contro	PROPN
bjos-8661512	97	12	l	l	PROPN
bjos-8661512	97	13	2	2	NUM
bjos-8661512	97	14	μg.m	μg.m	NOUN
bjos-8661512	97	15	l1	l1	PROPN
bjos-8661512	97	16	8	8	NUM
bjos-8661512	97	17	μg.m	μg.m	PROPN
bjos-8661512	97	18	l1	l1	PROPN
bjos-8661512	97	19	32	32	NUM
bjos-8661512	97	20	μg.m	μg.m	PROPN
bjos-8661512	97	21	l1	l1	PROPN
bjos-8661512	97	22	128	128	NUM
bjos-8661512	97	23	μg.m	μg.m	PROPN
bjos-8661512	97	24	l1	l1	PROPN
bjos-8661512	97	25	ce	ce	PROPN
bjos-8661512	97	26	ll	ll	PROPN
bjos-8661512	97	27	vi	vi	PROPN
bjos-8661512	97	28	ab	ab	PROPN
bjos-8661512	97	29	ili	ili	PROPN
bjos-8661512	98	1	ty	ty	INTJ
bjos-8661512	98	2	(	(	PUNCT
bjos-8661512	98	3	%	%	NOUN
bjos-8661512	98	4	)	)	PUNCT
bjos-8661512	98	5	ll-37	ll-37	PROPN
bjos-8661512	98	6	250	250	NUM
bjos-8661512	98	7	200	200	NUM
bjos-8661512	98	8	150	150	NUM
bjos-8661512	98	9	100	100	NUM
bjos-8661512	98	10	50	50	NUM
bjos-8661512	98	11	0	0	NUM
bjos-8661512	98	12	contro	contro	PROPN
bjos-8661512	98	13	l	l	PROPN
bjos-8661512	98	14	2	2	NUM
bjos-8661512	98	15	μg.m	μg.m	NOUN
bjos-8661512	98	16	l1	l1	PROPN
bjos-8661512	98	17	8	8	NUM
bjos-8661512	98	18	μg.m	μg.m	PROPN
bjos-8661512	98	19	l1	l1	PROPN
bjos-8661512	98	20	32	32	NUM
bjos-8661512	98	21	μg.m	μg.m	PROPN
bjos-8661512	98	22	l1	l1	PROPN
bjos-8661512	98	23	128	128	NUM
bjos-8661512	98	24	μg.m	μg.m	PROPN
bjos-8661512	98	25	l1	l1	PROPN
bjos-8661512	98	26	ce	ce	PROPN
bjos-8661512	99	1	ll	ll	PROPN
bjos-8661512	99	2	vi	vi	PROPN
bjos-8661512	99	3	ab	ab	PROPN
bjos-8661512	99	4	ili	ili	PROPN
bjos-8661512	100	1	ty	ty	INTJ
bjos-8661512	100	2	(	(	PUNCT
bjos-8661512	100	3	%	%	NOUN
bjos-8661512	100	4	)	)	PUNCT
bjos-8661512	100	5	doxycycline	doxycycline	NOUN
bjos-8661512	100	6	3	3	NUM
bjos-8661512	100	7	days	day	NOUN
bjos-8661512	100	8	7	7	NUM
bjos-8661512	100	9	days	day	NOUN
bjos-8661512	100	10	250	250	NUM
bjos-8661512	100	11	200	200	NUM
bjos-8661512	100	12	150	150	NUM
bjos-8661512	100	13	100	100	NUM
bjos-8661512	100	14	50	50	NUM
bjos-8661512	100	15	0	0	NUM
bjos-8661512	100	16	contro	contro	PROPN
bjos-8661512	100	17	l	l	PROPN
bjos-8661512	100	18	2	2	NUM
bjos-8661512	100	19	μg.m	μg.m	NOUN
bjos-8661512	100	20	l1	l1	PROPN
bjos-8661512	100	21	8	8	NUM
bjos-8661512	100	22	μg.m	μg.m	PROPN
bjos-8661512	100	23	l1	l1	PROPN
bjos-8661512	100	24	32	32	NUM
bjos-8661512	100	25	μg.m	μg.m	PROPN
bjos-8661512	100	26	l1	l1	PROPN
bjos-8661512	100	27	128	128	NUM
bjos-8661512	100	28	μg.m	μg.m	PROPN
bjos-8661512	100	29	l1	l1	PROPN
bjos-8661512	100	30	ce	ce	PROPN
bjos-8661512	101	1	ll	ll	PROPN
bjos-8661512	101	2	vi	vi	PROPN
bjos-8661512	101	3	ab	ab	PROPN
bjos-8661512	101	4	ili	ili	PROPN
bjos-8661512	102	1	ty	ty	INTJ
bjos-8661512	102	2	(	(	PUNCT
bjos-8661512	102	3	%	%	NOUN
bjos-8661512	102	4	)	)	PUNCT
bjos-8661512	102	5	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	102	6	250	250	NUM
bjos-8661512	102	7	200	200	NUM
bjos-8661512	102	8	150	150	NUM
bjos-8661512	102	9	100	100	NUM
bjos-8661512	102	10	50	50	NUM
bjos-8661512	102	11	0	0	NUM
bjos-8661512	102	12	contro	contro	PROPN
bjos-8661512	102	13	l	l	PROPN
bjos-8661512	102	14	2	2	NUM
bjos-8661512	102	15	μg.m	μg.m	NOUN
bjos-8661512	102	16	l1	l1	PROPN
bjos-8661512	102	17	8	8	NUM
bjos-8661512	102	18	μg.m	μg.m	PROPN
bjos-8661512	102	19	l1	l1	PROPN
bjos-8661512	102	20	32	32	NUM
bjos-8661512	102	21	μg.m	μg.m	PROPN
bjos-8661512	102	22	l1	l1	PROPN
bjos-8661512	102	23	128	128	NUM
bjos-8661512	102	24	μg.m	μg.m	PROPN
bjos-8661512	102	25	l1	l1	PROPN
bjos-8661512	102	26	*	*	PUNCT
bjos-8661512	103	1	*	*	PUNCT
bjos-8661512	103	2	*	*	PUNCT
bjos-8661512	104	1	*	*	PUNCT
bjos-8661512	104	2	*	*	PUNCT
bjos-8661512	104	3	*	*	PUNCT
bjos-8661512	104	4	*	*	PUNCT
bjos-8661512	104	5	*	*	PUNCT
bjos-8661512	104	6	*	*	PUNCT
bjos-8661512	104	7	*	*	PUNCT
bjos-8661512	104	8	*	*	PUNCT
bjos-8661512	104	9	*	*	PUNCT
bjos-8661512	104	10	*	*	PUNCT
bjos-8661512	104	11	*	*	PUNCT
bjos-8661512	104	12	*	*	PUNCT
bjos-8661512	104	13	*	*	PUNCT
bjos-8661512	105	1	*	*	PUNCT
bjos-8661512	105	2	*	*	PUNCT
bjos-8661512	105	3	*	*	PUNCT
bjos-8661512	106	1	*	*	PUNCT
bjos-8661512	107	1	*	*	PUNCT
bjos-8661512	107	2	*	*	PUNCT
bjos-8661512	108	1	*	*	PUNCT
bjos-8661512	108	2	*	*	PUNCT
bjos-8661512	108	3	*	*	PUNCT
bjos-8661512	109	1	*	*	PUNCT
bjos-8661512	110	1	*	*	PUNCT
bjos-8661512	110	2	*	*	PUNCT
bjos-8661512	111	1	*	*	PUNCT
bjos-8661512	111	2	*	*	PUNCT
bjos-8661512	112	1	*	*	PUNCT
bjos-8661512	112	2	*	*	PUNCT
bjos-8661512	112	3	*	*	PUNCT
bjos-8661512	112	4	*	*	PUNCT
bjos-8661512	113	1	*	*	PUNCT
bjos-8661512	113	2	*	*	PUNCT
bjos-8661512	114	1	*	*	PUNCT
bjos-8661512	114	2	*	*	PUNCT
bjos-8661512	114	3	*	*	PUNCT
bjos-8661512	114	4	*	*	PUNCT
bjos-8661512	115	1	*	*	PUNCT
bjos-8661512	115	2	*	*	PUNCT
bjos-8661512	115	3	*	*	PUNCT
bjos-8661512	115	4	*	*	PUNCT
bjos-8661512	116	1	*	*	PUNCT
bjos-8661512	117	1	*	*	PUNCT
bjos-8661512	117	2	*	*	PUNCT
bjos-8661512	118	1	*	*	PUNCT
bjos-8661512	118	2	*	*	PUNCT
bjos-8661512	118	3	*	*	PUNCT
bjos-8661512	118	4	*	*	PUNCT
bjos-8661512	119	1	*	*	PUNCT
bjos-8661512	120	1	*	*	PUNCT
bjos-8661512	120	2	*	*	PUNCT
bjos-8661512	120	3	6	6	NUM
bjos-8661512	120	4	amorim	amorim	NOUN
bjos-8661512	120	5	et	et	PROPN
bjos-8661512	120	6	al	al	PROPN
bjos-8661512	120	7	.	.	PUNCT
bjos-8661512	121	1	raw	raw	ADJ
bjos-8661512	121	2	264.7	264.7	NUM
bjos-8661512	121	3	cell	cell	NOUN
bjos-8661512	121	4	cultures	culture	NOUN
bjos-8661512	121	5	(	(	PUNCT
bjos-8661512	121	6	figure	figure	NOUN
bjos-8661512	121	7	2	2	NUM
bjos-8661512	121	8	)	)	PUNCT
bjos-8661512	121	9	.	.	PUNCT
bjos-8661512	122	1	after	after	ADP
bjos-8661512	122	2	3	3	NUM
bjos-8661512	122	3	days	day	NOUN
bjos-8661512	122	4	,	,	PUNCT
bjos-8661512	122	5	rrankl	rrankl	NOUN
bjos-8661512	122	6	-	-	PUNCT
bjos-8661512	122	7	stimulated	stimulate	VERB
bjos-8661512	122	8	cells	cell	NOUN
bjos-8661512	122	9	with	with	ADP
bjos-8661512	122	10	clavanin	clavanin	NOUN
bjos-8661512	122	11	a	a	DET
bjos-8661512	122	12	downregulated	downregulate	VERB
bjos-8661512	122	13	no	no	DET
bjos-8661512	122	14	levels	level	NOUN
bjos-8661512	122	15	at	at	ADP
bjos-8661512	122	16	all	all	DET
bjos-8661512	122	17	concentrations	concentration	NOUN
bjos-8661512	122	18	,	,	PUNCT
bjos-8661512	122	19	compared	compare	VERB
bjos-8661512	122	20	to	to	ADP
bjos-8661512	122	21	the	the	DET
bjos-8661512	122	22	control	control	NOUN
bjos-8661512	122	23	group	group	NOUN
bjos-8661512	122	24	,	,	PUNCT
bjos-8661512	122	25	while	while	SCONJ
bjos-8661512	122	26	on	on	ADP
bjos-8661512	122	27	the	the	DET
bjos-8661512	122	28	seventh	seventh	ADJ
bjos-8661512	122	29	day	day	NOUN
bjos-8661512	122	30	,	,	PUNCT
bjos-8661512	122	31	no	no	DET
bjos-8661512	122	32	levels	level	NOUN
bjos-8661512	122	33	were	be	AUX
bjos-8661512	122	34	similar	similar	ADJ
bjos-8661512	122	35	to	to	ADP
bjos-8661512	122	36	the	the	DET
bjos-8661512	122	37	control	control	NOUN
bjos-8661512	122	38	group	group	NOUN
bjos-8661512	122	39	(	(	PUNCT
bjos-8661512	122	40	p<0.0001	p<0.0001	NOUN
bjos-8661512	122	41	)	)	PUNCT
bjos-8661512	122	42	.	.	PUNCT
bjos-8661512	123	1	the	the	DET
bjos-8661512	123	2	downregulation	downregulation	NOUN
bjos-8661512	123	3	of	of	ADP
bjos-8661512	123	4	no	no	DET
bjos-8661512	123	5	production	production	NOUN
bjos-8661512	123	6	was	be	AUX
bjos-8661512	123	7	also	also	ADV
bjos-8661512	123	8	observed	observe	VERB
bjos-8661512	123	9	in	in	ADP
bjos-8661512	123	10	cultures	culture	NOUN
bjos-8661512	123	11	stimulated	stimulate	VERB
bjos-8661512	123	12	with	with	ADP
bjos-8661512	123	13	clavanin	clavanin	ADJ
bjos-8661512	123	14	figure	figure	NOUN
bjos-8661512	123	15	2	2	NUM
bjos-8661512	123	16	.	.	NOUN
bjos-8661512	123	17	nitric	nitric	ADJ
bjos-8661512	123	18	oxide	oxide	NOUN
bjos-8661512	123	19	production	production	NOUN
bjos-8661512	123	20	in	in	ADP
bjos-8661512	123	21	the	the	DET
bjos-8661512	123	22	presence	presence	NOUN
bjos-8661512	123	23	of	of	ADP
bjos-8661512	123	24	clavanin	clavanin	PROPN
bjos-8661512	123	25	a	a	PRON
bjos-8661512	123	26	,	,	PUNCT
bjos-8661512	123	27	clavanin	clavanin	PROPN
bjos-8661512	123	28	mo	mo	PROPN
bjos-8661512	123	29	,	,	PUNCT
bjos-8661512	123	30	ll-37	ll-37	PROPN
bjos-8661512	123	31	,	,	PUNCT
bjos-8661512	123	32	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	123	33	and	and	CCONJ
bjos-8661512	123	34	doxycycline	doxycycline	NOUN
bjos-8661512	123	35	at	at	ADP
bjos-8661512	123	36	2	2	NUM
bjos-8661512	123	37	,	,	PUNCT
bjos-8661512	123	38	8	8	NUM
bjos-8661512	123	39	,	,	PUNCT
bjos-8661512	123	40	32	32	NUM
bjos-8661512	123	41	and	and	CCONJ
bjos-8661512	123	42	128	128	NUM
bjos-8661512	123	43	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	123	44	on	on	ADP
bjos-8661512	123	45	rrankl	rrankl	NOUN
bjos-8661512	123	46	-	-	PUNCT
bjos-8661512	123	47	stimulated	stimulate	VERB
bjos-8661512	123	48	-	-	PUNCT
bjos-8661512	123	49	raw	raw	ADJ
bjos-8661512	123	50	cells	cell	NOUN
bjos-8661512	123	51	,	,	PUNCT
bjos-8661512	123	52	after	after	ADP
bjos-8661512	123	53	3	3	NUM
bjos-8661512	123	54	and	and	CCONJ
bjos-8661512	123	55	7	7	NUM
bjos-8661512	123	56	days	day	NOUN
bjos-8661512	123	57	,	,	PUNCT
bjos-8661512	123	58	as	as	SCONJ
bjos-8661512	123	59	described	describe	VERB
bjos-8661512	123	60	in	in	ADP
bjos-8661512	123	61	the	the	DET
bjos-8661512	123	62	method	method	NOUN
bjos-8661512	123	63	of	of	ADP
bjos-8661512	123	64	green	green	PROPN
bjos-8661512	123	65	et	et	PROPN
bjos-8661512	123	66	al	al	PROPN
bjos-8661512	123	67	.	.	PROPN
bjos-8661512	123	68	,	,	PUNCT
bjos-8661512	123	69	with	with	ADP
bjos-8661512	123	70	adaptations	adaptation	NOUN
bjos-8661512	123	71	.	.	PUNCT
bjos-8661512	124	1	cultures	culture	NOUN
bjos-8661512	124	2	were	be	AUX
bjos-8661512	124	3	stimulated	stimulate	VERB
bjos-8661512	124	4	with	with	ADP
bjos-8661512	124	5	100	100	NUM
bjos-8661512	124	6	ng.ml-1	ng.ml-1	NOUN
bjos-8661512	124	7	of	of	ADP
bjos-8661512	124	8	rrankl	rrankl	NOUN
bjos-8661512	124	9	.	.	PUNCT
bjos-8661512	125	1	control	control	PROPN
bjos-8661512	125	2	group	group	PROPN
bjos-8661512	125	3	consisted	consist	VERB
bjos-8661512	125	4	of	of	ADP
bjos-8661512	125	5	2.5x103	2.5x103	ADJ
bjos-8661512	125	6	raw	raw	ADJ
bjos-8661512	125	7	cells	cell	NOUN
bjos-8661512	125	8	stimulated	stimulate	VERB
bjos-8661512	125	9	with	with	ADP
bjos-8661512	125	10	100	100	NUM
bjos-8661512	125	11	ng.ml-1	ng.ml-1	NOUN
bjos-8661512	125	12	of	of	ADP
bjos-8661512	125	13	rrankl	rrankl	NOUN
bjos-8661512	125	14	.	.	PUNCT
bjos-8661512	126	1	bars	bar	NOUN
bjos-8661512	126	2	represent	represent	VERB
bjos-8661512	126	3	the	the	DET
bjos-8661512	126	4	standard	standard	ADJ
bjos-8661512	126	5	error	error	NOUN
bjos-8661512	126	6	of	of	ADP
bjos-8661512	126	7	the	the	DET
bjos-8661512	126	8	mean	mean	NOUN
bjos-8661512	126	9	of	of	ADP
bjos-8661512	126	10	nitrite	nitrite	NOUN
bjos-8661512	126	11	oxide	oxide	NOUN
bjos-8661512	126	12	production	production	NOUN
bjos-8661512	126	13	.	.	PUNCT
bjos-8661512	127	1	all	all	DET
bjos-8661512	127	2	experiments	experiment	NOUN
bjos-8661512	127	3	were	be	AUX
bjos-8661512	127	4	done	do	VERB
bjos-8661512	127	5	in	in	ADP
bjos-8661512	127	6	technical	technical	ADJ
bjos-8661512	127	7	and	and	CCONJ
bjos-8661512	127	8	biological	biological	ADJ
bjos-8661512	127	9	triplicates	triplicate	NOUN
bjos-8661512	127	10	.	.	PUNCT
bjos-8661512	128	1	statistical	statistical	ADJ
bjos-8661512	128	2	differences	difference	NOUN
bjos-8661512	128	3	by	by	ADP
bjos-8661512	128	4	two	two	NUM
bjos-8661512	128	5	-	-	PUNCT
bjos-8661512	128	6	way	way	NOUN
bjos-8661512	128	7	anova	anova	PROPN
bjos-8661512	128	8	test	test	NOUN
bjos-8661512	128	9	and	and	CCONJ
bjos-8661512	128	10	tukey	tukey	PROPN
bjos-8661512	128	11	’s	’s	PART
bjos-8661512	128	12	post	post	X
bjos-8661512	128	13	hoc	hoc	X
bjos-8661512	128	14	were	be	AUX
bjos-8661512	128	15	represented	represent	VERB
bjos-8661512	128	16	by	by	ADP
bjos-8661512	128	17	*	*	PROPN
bjos-8661512	128	18	p<0.05	p<0.05	PROPN
bjos-8661512	128	19	,	,	PUNCT
bjos-8661512	128	20	*	*	PUNCT
bjos-8661512	128	21	*	*	X
bjos-8661512	128	22	p<0.005	p<0.005	ADP
bjos-8661512	128	23	,	,	PUNCT
bjos-8661512	128	24	*	*	PUNCT
bjos-8661512	128	25	*	*	PUNCT
bjos-8661512	128	26	*	*	NOUN
bjos-8661512	128	27	p<0.0005	p<0.0005	NOUN
bjos-8661512	128	28	and	and	CCONJ
bjos-8661512	128	29	*	*	NOUN
bjos-8661512	128	30	*	*	PUNCT
bjos-8661512	128	31	*	*	PUNCT
bjos-8661512	128	32	*	*	PUNCT
bjos-8661512	128	33	p<0.0001	p<0.0001	VERB
bjos-8661512	128	34	compared	compare	VERB
bjos-8661512	128	35	to	to	ADP
bjos-8661512	128	36	each	each	DET
bjos-8661512	128	37	concentration	concentration	NOUN
bjos-8661512	128	38	and	and	CCONJ
bjos-8661512	128	39	time	time	NOUN
bjos-8661512	128	40	-	-	PUNCT
bjos-8661512	128	41	tested	test	VERB
bjos-8661512	128	42	conditions	condition	NOUN
bjos-8661512	128	43	;	;	PUNCT
bjos-8661512	128	44	dark	dark	ADJ
bjos-8661512	128	45	green	green	ADJ
bjos-8661512	128	46	bars	bar	NOUN
bjos-8661512	128	47	represent	represent	VERB
bjos-8661512	128	48	statistical	statistical	ADJ
bjos-8661512	128	49	differences	difference	NOUN
bjos-8661512	128	50	observed	observe	VERB
bjos-8661512	128	51	on	on	ADP
bjos-8661512	128	52	day	day	NOUN
bjos-8661512	128	53	3	3	NUM
bjos-8661512	128	54	;	;	PUNCT
bjos-8661512	128	55	light	light	ADJ
bjos-8661512	128	56	green	green	ADJ
bjos-8661512	128	57	bars	bar	NOUN
bjos-8661512	128	58	represent	represent	VERB
bjos-8661512	128	59	statistical	statistical	ADJ
bjos-8661512	128	60	differences	difference	NOUN
bjos-8661512	128	61	observed	observe	VERB
bjos-8661512	128	62	on	on	ADP
bjos-8661512	128	63	day	day	NOUN
bjos-8661512	128	64	7	7	NUM
bjos-8661512	128	65	.	.	PUNCT
bjos-8661512	129	1	n	n	PRON
bjos-8661512	129	2	itr	itr	NOUN
bjos-8661512	129	3	ite	ite	PROPN
bjos-8661512	129	4	(	(	PUNCT
bjos-8661512	129	5	μ	μ	PROPN
bjos-8661512	129	6	m	m	NOUN
bjos-8661512	129	7	)	)	PUNCT
bjos-8661512	129	8	clavanin	clavanin	NOUN
bjos-8661512	129	9	a	a	PRON
bjos-8661512	129	10	*	*	PUNCT
bjos-8661512	129	11	*	*	PUNCT
bjos-8661512	129	12	*	*	PUNCT
bjos-8661512	129	13	*	*	SYM
bjos-8661512	129	14	5	5	NUM
bjos-8661512	129	15	4	4	NUM
bjos-8661512	129	16	3	3	NUM
bjos-8661512	129	17	2	2	NUM
bjos-8661512	129	18	1	1	NUM
bjos-8661512	129	19	0	0	NUM
bjos-8661512	129	20	contro	contro	PROPN
bjos-8661512	129	21	l	l	PROPN
bjos-8661512	129	22	2	2	NUM
bjos-8661512	129	23	μg.m	μg.m	NOUN
bjos-8661512	129	24	l1	l1	PROPN
bjos-8661512	129	25	8	8	NUM
bjos-8661512	129	26	μg.m	μg.m	PROPN
bjos-8661512	129	27	l1	l1	PROPN
bjos-8661512	129	28	32	32	NUM
bjos-8661512	129	29	μg.m	μg.m	PROPN
bjos-8661512	129	30	l1	l1	PROPN
bjos-8661512	129	31	128	128	NUM
bjos-8661512	129	32	μg.m	μg.m	PROPN
bjos-8661512	129	33	l1	l1	PROPN
bjos-8661512	129	34	n	n	PROPN
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bjos-8661512	129	36	ite	ite	PROPN
bjos-8661512	129	37	(	(	PUNCT
bjos-8661512	129	38	μ	μ	PROPN
bjos-8661512	129	39	m	m	NOUN
bjos-8661512	129	40	)	)	PUNCT
bjos-8661512	129	41	clavanin	clavanin	PROPN
bjos-8661512	129	42	mo5	mo5	PROPN
bjos-8661512	129	43	4	4	NUM
bjos-8661512	129	44	3	3	NUM
bjos-8661512	129	45	2	2	NUM
bjos-8661512	129	46	1	1	NUM
bjos-8661512	129	47	0	0	NUM
bjos-8661512	129	48	contro	contro	PROPN
bjos-8661512	129	49	l	l	PROPN
bjos-8661512	129	50	2	2	NUM
bjos-8661512	129	51	μg.m	μg.m	NOUN
bjos-8661512	129	52	l1	l1	PROPN
bjos-8661512	129	53	8	8	NUM
bjos-8661512	129	54	μg.m	μg.m	PROPN
bjos-8661512	129	55	l1	l1	PROPN
bjos-8661512	129	56	32	32	NUM
bjos-8661512	129	57	μg.m	μg.m	PROPN
bjos-8661512	129	58	l1	l1	PROPN
bjos-8661512	129	59	128	128	NUM
bjos-8661512	129	60	μg.m	μg.m	PROPN
bjos-8661512	129	61	l1	l1	PROPN
bjos-8661512	129	62	n	n	PROPN
bjos-8661512	129	63	itr	itr	PROPN
bjos-8661512	129	64	ite	ite	PROPN
bjos-8661512	129	65	(	(	PUNCT
bjos-8661512	129	66	μ	μ	PROPN
bjos-8661512	129	67	m	m	NOUN
bjos-8661512	129	68	)	)	PUNCT
bjos-8661512	129	69	ll-37	ll-37	NOUN
bjos-8661512	129	70	5	5	NUM
bjos-8661512	129	71	4	4	NUM
bjos-8661512	129	72	3	3	NUM
bjos-8661512	129	73	2	2	NUM
bjos-8661512	129	74	1	1	NUM
bjos-8661512	129	75	0	0	NUM
bjos-8661512	129	76	contro	contro	PROPN
bjos-8661512	129	77	l	l	PROPN
bjos-8661512	129	78	2	2	NUM
bjos-8661512	129	79	μg.m	μg.m	NOUN
bjos-8661512	129	80	l1	l1	PROPN
bjos-8661512	129	81	8	8	NUM
bjos-8661512	129	82	μg.m	μg.m	PROPN
bjos-8661512	129	83	l1	l1	PROPN
bjos-8661512	129	84	32	32	NUM
bjos-8661512	129	85	μg.m	μg.m	PROPN
bjos-8661512	129	86	l1	l1	PROPN
bjos-8661512	129	87	128	128	NUM
bjos-8661512	129	88	μg.m	μg.m	PROPN
bjos-8661512	129	89	l1	l1	PROPN
bjos-8661512	129	90	n	n	PROPN
bjos-8661512	129	91	itr	itr	PROPN
bjos-8661512	129	92	ite	ite	PROPN
bjos-8661512	129	93	(	(	PUNCT
bjos-8661512	129	94	μ	μ	PROPN
bjos-8661512	129	95	m	m	NOUN
bjos-8661512	129	96	)	)	PUNCT
bjos-8661512	129	97	doxycycline	doxycycline	NOUN
bjos-8661512	129	98	3	3	NUM
bjos-8661512	129	99	days	day	NOUN
bjos-8661512	129	100	7	7	NUM
bjos-8661512	129	101	days	day	NOUN
bjos-8661512	129	102	5	5	NUM
bjos-8661512	129	103	4	4	NUM
bjos-8661512	130	1	3	3	NUM
bjos-8661512	130	2	2	2	NUM
bjos-8661512	130	3	1	1	NUM
bjos-8661512	130	4	0	0	NUM
bjos-8661512	130	5	contro	contro	PROPN
bjos-8661512	130	6	l	l	PROPN
bjos-8661512	130	7	2	2	NUM
bjos-8661512	130	8	μg.m	μg.m	NOUN
bjos-8661512	130	9	l1	l1	PROPN
bjos-8661512	130	10	8	8	NUM
bjos-8661512	130	11	μg.m	μg.m	PROPN
bjos-8661512	130	12	l1	l1	PROPN
bjos-8661512	130	13	32	32	NUM
bjos-8661512	130	14	μg.m	μg.m	PROPN
bjos-8661512	130	15	l1	l1	PROPN
bjos-8661512	130	16	128	128	NUM
bjos-8661512	130	17	μg.m	μg.m	PROPN
bjos-8661512	130	18	l1	l1	PROPN
bjos-8661512	130	19	n	n	PROPN
bjos-8661512	130	20	itr	itr	PROPN
bjos-8661512	130	21	ite	ite	PROPN
bjos-8661512	130	22	(	(	PUNCT
bjos-8661512	130	23	μ	μ	PROPN
bjos-8661512	130	24	m	m	NOUN
bjos-8661512	130	25	)	)	PUNCT
bjos-8661512	130	26	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	130	27	5	5	NUM
bjos-8661512	130	28	4	4	NUM
bjos-8661512	130	29	3	3	NUM
bjos-8661512	130	30	2	2	NUM
bjos-8661512	130	31	1	1	NUM
bjos-8661512	130	32	0	0	NUM
bjos-8661512	130	33	contro	contro	PROPN
bjos-8661512	130	34	l	l	PROPN
bjos-8661512	130	35	2	2	NUM
bjos-8661512	130	36	μg.m	μg.m	NOUN
bjos-8661512	130	37	l1	l1	PROPN
bjos-8661512	130	38	8	8	NUM
bjos-8661512	130	39	μg.m	μg.m	PROPN
bjos-8661512	130	40	l1	l1	PROPN
bjos-8661512	130	41	32	32	NUM
bjos-8661512	130	42	μg.m	μg.m	PROPN
bjos-8661512	130	43	l1	l1	PROPN
bjos-8661512	130	44	128	128	NUM
bjos-8661512	130	45	μg.m	μg.m	PROPN
bjos-8661512	130	46	l1	l1	PROPN
bjos-8661512	130	47	*	*	PUNCT
bjos-8661512	131	1	*	*	PUNCT
bjos-8661512	131	2	*	*	PUNCT
bjos-8661512	131	3	*	*	PUNCT
bjos-8661512	131	4	*	*	PUNCT
bjos-8661512	131	5	*	*	PUNCT
bjos-8661512	131	6	*	*	PUNCT
bjos-8661512	131	7	*	*	PUNCT
bjos-8661512	131	8	*	*	PUNCT
bjos-8661512	131	9	*	*	PUNCT
bjos-8661512	131	10	*	*	PUNCT
bjos-8661512	131	11	*	*	PUNCT
bjos-8661512	132	1	*	*	PUNCT
bjos-8661512	132	2	*	*	PUNCT
bjos-8661512	132	3	*	*	PUNCT
bjos-8661512	132	4	*	*	PUNCT
bjos-8661512	133	1	*	*	PUNCT
bjos-8661512	133	2	*	*	PUNCT
bjos-8661512	134	1	*	*	PUNCT
bjos-8661512	134	2	*	*	PUNCT
bjos-8661512	134	3	*	*	PUNCT
bjos-8661512	134	4	*	*	PUNCT
bjos-8661512	134	5	*	*	PUNCT
bjos-8661512	135	1	*	*	PUNCT
bjos-8661512	135	2	*	*	PUNCT
bjos-8661512	135	3	*	*	PUNCT
bjos-8661512	136	1	*	*	PUNCT
bjos-8661512	137	1	*	*	PUNCT
bjos-8661512	137	2	*	*	PUNCT
bjos-8661512	137	3	*	*	PUNCT
bjos-8661512	137	4	*	*	PUNCT
bjos-8661512	138	1	*	*	PUNCT
bjos-8661512	138	2	*	*	PUNCT
bjos-8661512	138	3	*	*	PUNCT
bjos-8661512	138	4	*	*	PUNCT
bjos-8661512	139	1	*	*	PUNCT
bjos-8661512	139	2	*	*	PUNCT
bjos-8661512	139	3	*	*	PUNCT
bjos-8661512	139	4	*	*	PUNCT
bjos-8661512	139	5	*	*	PUNCT
bjos-8661512	139	6	*	*	PUNCT
bjos-8661512	140	1	*	*	PUNCT
bjos-8661512	140	2	*	*	PUNCT
bjos-8661512	141	1	*	*	PUNCT
bjos-8661512	141	2	*	*	PUNCT
bjos-8661512	141	3	*	*	PUNCT
bjos-8661512	141	4	*	*	PUNCT
bjos-8661512	141	5	*	*	PUNCT
bjos-8661512	141	6	*	*	PUNCT
bjos-8661512	141	7	*	*	PUNCT
bjos-8661512	141	8	*	*	PUNCT
bjos-8661512	142	1	*	*	PUNCT
bjos-8661512	142	2	*	*	PUNCT
bjos-8661512	142	3	*	*	PUNCT
bjos-8661512	142	4	*	*	PUNCT
bjos-8661512	142	5	*	*	PUNCT
bjos-8661512	142	6	*	*	PUNCT
bjos-8661512	142	7	*	*	PUNCT
bjos-8661512	142	8	*	*	PUNCT
bjos-8661512	143	1	*	*	PUNCT
bjos-8661512	143	2	*	*	PUNCT
bjos-8661512	143	3	*	*	PUNCT
bjos-8661512	143	4	*	*	PUNCT
bjos-8661512	144	1	*	*	PUNCT
bjos-8661512	144	2	*	*	PUNCT
bjos-8661512	144	3	*	*	PUNCT
bjos-8661512	144	4	*	*	PUNCT
bjos-8661512	145	1	*	*	PUNCT
bjos-8661512	145	2	*	*	PUNCT
bjos-8661512	146	1	*	*	PUNCT
bjos-8661512	147	1	*	*	PUNCT
bjos-8661512	147	2	*	*	PUNCT
bjos-8661512	147	3	*	*	PUNCT
bjos-8661512	147	4	*	*	PUNCT
bjos-8661512	147	5	*	*	PUNCT
bjos-8661512	147	6	*	*	PUNCT
bjos-8661512	147	7	*	*	PUNCT
bjos-8661512	147	8	*	*	PUNCT
bjos-8661512	147	9	*	*	PUNCT
bjos-8661512	147	10	*	*	PUNCT
bjos-8661512	147	11	*	*	PUNCT
bjos-8661512	147	12	*	*	PUNCT
bjos-8661512	147	13	*	*	PUNCT
bjos-8661512	147	14	*	*	PUNCT
bjos-8661512	147	15	*	*	PUNCT
bjos-8661512	147	16	*	*	PUNCT
bjos-8661512	147	17	*	*	PUNCT
bjos-8661512	147	18	*	*	PUNCT
bjos-8661512	147	19	*	*	PUNCT
bjos-8661512	147	20	*	*	PUNCT
bjos-8661512	147	21	*	*	PUNCT
bjos-8661512	147	22	7	7	NUM
bjos-8661512	147	23	amorim	amorim	PROPN
bjos-8661512	147	24	et	et	PROPN
bjos-8661512	147	25	al	al	PROPN
bjos-8661512	147	26	.	.	PROPN
bjos-8661512	147	27	mo	mo	PROPN
bjos-8661512	147	28	at	at	ADP
bjos-8661512	147	29	128	128	NUM
bjos-8661512	147	30	μg.ml-1	μg.ml-1	ADV
bjos-8661512	147	31	,	,	PUNCT
bjos-8661512	147	32	after	after	ADP
bjos-8661512	147	33	7	7	NUM
bjos-8661512	147	34	days	day	NOUN
bjos-8661512	147	35	(	(	PUNCT
bjos-8661512	147	36	p	p	X
bjos-8661512	147	37	<	<	X
bjos-8661512	147	38	0.05	0.05	NUM
bjos-8661512	147	39	)	)	PUNCT
bjos-8661512	147	40	.	.	PUNCT
bjos-8661512	148	1	however	however	ADV
bjos-8661512	148	2	,	,	PUNCT
bjos-8661512	148	3	the	the	DET
bjos-8661512	148	4	presence	presence	NOUN
bjos-8661512	148	5	of	of	ADP
bjos-8661512	148	6	128	128	NUM
bjos-8661512	148	7	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	148	8	of	of	ADP
bjos-8661512	148	9	ll-37	ll-37	NOUN
bjos-8661512	148	10	after	after	ADP
bjos-8661512	148	11	7	7	NUM
bjos-8661512	148	12	days	day	NOUN
bjos-8661512	148	13	,	,	PUNCT
bjos-8661512	148	14	increased	increase	VERB
bjos-8661512	148	15	the	the	DET
bjos-8661512	148	16	no	no	DET
bjos-8661512	148	17	levels	level	NOUN
bjos-8661512	148	18	compared	compare	VERB
bjos-8661512	148	19	to	to	ADP
bjos-8661512	148	20	the	the	DET
bjos-8661512	148	21	control	control	NOUN
bjos-8661512	148	22	group	group	NOUN
bjos-8661512	148	23	(	(	PUNCT
bjos-8661512	148	24	p<0.0001	p<0.0001	NOUN
bjos-8661512	148	25	)	)	PUNCT
bjos-8661512	148	26	,	,	PUNCT
bjos-8661512	148	27	while	while	SCONJ
bjos-8661512	148	28	the	the	DET
bjos-8661512	148	29	others	other	NOUN
bjos-8661512	148	30	concentrations	concentration	NOUN
bjos-8661512	148	31	at	at	ADP
bjos-8661512	148	32	3	3	NUM
bjos-8661512	148	33	and	and	CCONJ
bjos-8661512	148	34	7	7	NUM
bjos-8661512	148	35	days	day	NOUN
bjos-8661512	148	36	were	be	AUX
bjos-8661512	148	37	similar	similar	ADJ
bjos-8661512	148	38	to	to	ADP
bjos-8661512	148	39	baseline	baseline	NOUN
bjos-8661512	148	40	levels	level	NOUN
bjos-8661512	148	41	.	.	PUNCT
bjos-8661512	149	1	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	149	2	was	be	AUX
bjos-8661512	149	3	able	able	ADJ
bjos-8661512	149	4	to	to	PART
bjos-8661512	149	5	upregulate	upregulate	VERB
bjos-8661512	149	6	no	no	DET
bjos-8661512	149	7	production	production	NOUN
bjos-8661512	149	8	at	at	ADP
bjos-8661512	149	9	8	8	NUM
bjos-8661512	149	10	(	(	PUNCT
bjos-8661512	149	11	p<0.005	p<0.005	NOUN
bjos-8661512	149	12	)	)	PUNCT
bjos-8661512	149	13	,	,	PUNCT
bjos-8661512	149	14	32	32	NUM
bjos-8661512	149	15	(	(	PUNCT
bjos-8661512	149	16	p<0.05	p<0.05	NOUN
bjos-8661512	149	17	)	)	PUNCT
bjos-8661512	149	18	and	and	CCONJ
bjos-8661512	149	19	128	128	NUM
bjos-8661512	149	20	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	149	21	(	(	PUNCT
bjos-8661512	149	22	p<0.005	p<0.005	NOUN
bjos-8661512	149	23	)	)	PUNCT
bjos-8661512	149	24	after	after	ADP
bjos-8661512	149	25	7	7	NUM
bjos-8661512	149	26	days	day	NOUN
bjos-8661512	149	27	of	of	ADP
bjos-8661512	149	28	cell	cell	NOUN
bjos-8661512	149	29	incubation	incubation	NOUN
bjos-8661512	149	30	.	.	PUNCT
bjos-8661512	150	1	no	no	DET
bjos-8661512	150	2	levels	level	NOUN
bjos-8661512	150	3	in	in	ADP
bjos-8661512	150	4	the	the	DET
bjos-8661512	150	5	presence	presence	NOUN
bjos-8661512	150	6	of	of	ADP
bjos-8661512	150	7	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	150	8	at	at	ADP
bjos-8661512	150	9	other	other	ADJ
bjos-8661512	150	10	different	different	ADJ
bjos-8661512	150	11	concentrations	concentration	NOUN
bjos-8661512	150	12	were	be	AUX
bjos-8661512	150	13	similar	similar	ADJ
bjos-8661512	150	14	to	to	ADP
bjos-8661512	150	15	the	the	DET
bjos-8661512	150	16	control	control	NOUN
bjos-8661512	150	17	group	group	NOUN
bjos-8661512	150	18	(	(	PUNCT
bjos-8661512	150	19	p<0.05	p<0.05	PROPN
bjos-8661512	150	20	)	)	PUNCT
bjos-8661512	150	21	,	,	PUNCT
bjos-8661512	150	22	after	after	ADP
bjos-8661512	150	23	3	3	NUM
bjos-8661512	150	24	and	and	CCONJ
bjos-8661512	150	25	7	7	NUM
bjos-8661512	150	26	days	day	NOUN
bjos-8661512	150	27	.	.	PUNCT
bjos-8661512	151	1	the	the	DET
bjos-8661512	151	2	lower	low	ADJ
bjos-8661512	151	3	concentration	concentration	NOUN
bjos-8661512	151	4	of	of	ADP
bjos-8661512	151	5	doxycycline	doxycycline	NOUN
bjos-8661512	151	6	up	up	ADV
bjos-8661512	151	7	-	-	PUNCT
bjos-8661512	151	8	regulated	regulate	VERB
bjos-8661512	151	9	no	no	DET
bjos-8661512	151	10	production	production	NOUN
bjos-8661512	151	11	after	after	ADP
bjos-8661512	151	12	7	7	NUM
bjos-8661512	151	13	days	day	NOUN
bjos-8661512	151	14	compared	compare	VERB
bjos-8661512	151	15	to	to	ADP
bjos-8661512	151	16	all	all	DET
bjos-8661512	151	17	concentrations	concentration	NOUN
bjos-8661512	151	18	,	,	PUNCT
bjos-8661512	151	19	including	include	VERB
bjos-8661512	151	20	the	the	DET
bjos-8661512	151	21	control	control	NOUN
bjos-8661512	151	22	group	group	NOUN
bjos-8661512	151	23	(	(	PUNCT
bjos-8661512	151	24	p<0.0001	p<0.0001	NOUN
bjos-8661512	151	25	)	)	PUNCT
bjos-8661512	151	26	.	.	PUNCT
bjos-8661512	152	1	overall	overall	ADJ
bjos-8661512	152	2	,	,	PUNCT
bjos-8661512	152	3	reduced	reduced	ADJ
bjos-8661512	152	4	levels	level	NOUN
bjos-8661512	152	5	of	of	ADP
bjos-8661512	152	6	no	no	PRON
bjos-8661512	152	7	were	be	AUX
bjos-8661512	152	8	observed	observe	VERB
bjos-8661512	152	9	in	in	ADP
bjos-8661512	152	10	some	some	DET
bjos-8661512	152	11	concentrations	concentration	NOUN
bjos-8661512	152	12	of	of	ADP
bjos-8661512	152	13	all	all	DET
bjos-8661512	152	14	substances	substance	NOUN
bjos-8661512	152	15	,	,	PUNCT
bjos-8661512	152	16	except	except	SCONJ
bjos-8661512	152	17	for	for	ADP
bjos-8661512	152	18	doxycycline	doxycycline	NOUN
bjos-8661512	152	19	and	and	CCONJ
bjos-8661512	152	20	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	152	21	7	7	NUM
bjos-8661512	152	22	days	day	NOUN
bjos-8661512	152	23	after	after	ADP
bjos-8661512	152	24	the	the	DET
bjos-8661512	152	25	test	test	NOUN
bjos-8661512	152	26	.	.	PUNCT
bjos-8661512	153	1	number	number	NOUN
bjos-8661512	153	2	of	of	ADP
bjos-8661512	153	3	differentiated	differentiated	ADJ
bjos-8661512	153	4	osteoclast	osteoclast	ADJ
bjos-8661512	153	5	-	-	PUNCT
bjos-8661512	153	6	like	like	ADJ
bjos-8661512	153	7	cells	cell	NOUN
bjos-8661512	153	8	raw	raw	ADJ
bjos-8661512	153	9	cell	cell	NOUN
bjos-8661512	153	10	cultures	culture	NOUN
bjos-8661512	153	11	stimulated	stimulate	VERB
bjos-8661512	153	12	with	with	ADP
bjos-8661512	153	13	hdps	hdps	ADJ
bjos-8661512	153	14	,	,	PUNCT
bjos-8661512	153	15	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	153	16	,	,	PUNCT
bjos-8661512	153	17	doxycycline	doxycycline	NOUN
bjos-8661512	153	18	and	and	CCONJ
bjos-8661512	153	19	rrankl	rrankl	NOUN
bjos-8661512	153	20	were	be	AUX
bjos-8661512	153	21	submitted	submit	VERB
bjos-8661512	153	22	to	to	PART
bjos-8661512	153	23	trap	trap	VERB
bjos-8661512	153	24	staining	stain	VERB
bjos-8661512	153	25	after	after	ADP
bjos-8661512	153	26	7	7	NUM
bjos-8661512	153	27	days	day	NOUN
bjos-8661512	153	28	of	of	ADP
bjos-8661512	153	29	incubation	incubation	NOUN
bjos-8661512	153	30	(	(	PUNCT
bjos-8661512	153	31	figure	figure	NOUN
bjos-8661512	153	32	3a	3a	NUM
bjos-8661512	153	33	-	-	SYM
bjos-8661512	153	34	b	b	NOUN
bjos-8661512	153	35	)	)	PUNCT
bjos-8661512	153	36	,	,	PUNCT
bjos-8661512	153	37	for	for	ADP
bjos-8661512	153	38	quantification	quantification	NOUN
bjos-8661512	153	39	of	of	ADP
bjos-8661512	153	40	differentiated	differentiated	ADJ
bjos-8661512	153	41	osteoclast	osteoclast	ADJ
bjos-8661512	153	42	-	-	PUNCT
bjos-8661512	153	43	like	like	ADJ
bjos-8661512	153	44	cells	cell	NOUN
bjos-8661512	153	45	.	.	PUNCT
bjos-8661512	154	1	all	all	PRON
bjos-8661512	154	2	hdps	hdps	ADJ
bjos-8661512	154	3	,	,	PUNCT
bjos-8661512	154	4	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	154	5	,	,	PUNCT
bjos-8661512	154	6	and	and	CCONJ
bjos-8661512	154	7	doxycycline	doxycycline	NOUN
bjos-8661512	154	8	,	,	PUNCT
bjos-8661512	154	9	at	at	ADP
bjos-8661512	154	10	all	all	DET
bjos-8661512	154	11	tested	test	VERB
bjos-8661512	154	12	concentrations	concentration	NOUN
bjos-8661512	154	13	,	,	PUNCT
bjos-8661512	154	14	were	be	AUX
bjos-8661512	154	15	capable	capable	ADJ
bjos-8661512	154	16	of	of	ADP
bjos-8661512	154	17	reducing	reduce	VERB
bjos-8661512	154	18	the	the	DET
bjos-8661512	154	19	differentiation	differentiation	NOUN
bjos-8661512	154	20	of	of	ADP
bjos-8661512	154	21	osteoclast	osteoclast	ADJ
bjos-8661512	154	22	-	-	PUNCT
bjos-8661512	154	23	like	like	ADJ
bjos-8661512	154	24	cells	cell	NOUN
bjos-8661512	154	25	(	(	PUNCT
bjos-8661512	154	26	figure	figure	NOUN
bjos-8661512	154	27	3b	3b	NUM
bjos-8661512	154	28	)	)	PUNCT
bjos-8661512	154	29	.	.	PUNCT
bjos-8661512	155	1	indeed	indeed	ADV
bjos-8661512	155	2	,	,	PUNCT
bjos-8661512	155	3	clavanin	clavanin	VERB
bjos-8661512	155	4	a	a	DET
bjos-8661512	155	5	reduced	reduced	ADJ
bjos-8661512	155	6	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	155	7	in	in	ADP
bjos-8661512	155	8	an	an	DET
bjos-8661512	155	9	inverse	inverse	NOUN
bjos-8661512	155	10	dose	dose	NOUN
bjos-8661512	155	11	-	-	PUNCT
bjos-8661512	155	12	dependent	dependent	ADJ
bjos-8661512	155	13	concentration	concentration	NOUN
bjos-8661512	155	14	.	.	PUNCT
bjos-8661512	156	1	clavanin	clavanin	NOUN
bjos-8661512	156	2	a	a	PRON
bjos-8661512	156	3	at	at	ADP
bjos-8661512	156	4	128	128	NUM
bjos-8661512	156	5	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	156	6	demonstrated	demonstrate	VERB
bjos-8661512	156	7	the	the	DET
bjos-8661512	156	8	lowest	low	ADJ
bjos-8661512	156	9	number	number	NOUN
bjos-8661512	156	10	of	of	ADP
bjos-8661512	156	11	differentiated	differentiated	ADJ
bjos-8661512	156	12	osteoclast	osteoclast	ADJ
bjos-8661512	156	13	-	-	PUNCT
bjos-8661512	156	14	like	like	ADJ
bjos-8661512	156	15	cells	cell	NOUN
bjos-8661512	156	16	(	(	PUNCT
bjos-8661512	156	17	p<0.05	p<0.05	NOUN
bjos-8661512	156	18	)	)	PUNCT
bjos-8661512	156	19	.	.	PUNCT
bjos-8661512	157	1	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	157	2	was	be	AUX
bjos-8661512	157	3	similarly	similarly	ADV
bjos-8661512	157	4	reduced	reduce	VERB
bjos-8661512	157	5	by	by	ADP
bjos-8661512	157	6	clavanin	clavanin	PROPN
bjos-8661512	157	7	mo	mo	PROPN
bjos-8661512	157	8	at	at	ADV
bjos-8661512	157	9	all	all	DET
bjos-8661512	157	10	tested	test	VERB
bjos-8661512	157	11	concentrations	concentration	NOUN
bjos-8661512	157	12	(	(	PUNCT
bjos-8661512	157	13	p<0.05	p<0.05	NOUN
bjos-8661512	157	14	)	)	PUNCT
bjos-8661512	157	15	.	.	PUNCT
bjos-8661512	158	1	likewise	likewise	ADV
bjos-8661512	158	2	,	,	PUNCT
bjos-8661512	158	3	ll-37	ll-37	NOUN
bjos-8661512	158	4	also	also	ADV
bjos-8661512	158	5	downregulated	downregulate	VERB
bjos-8661512	158	6	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	158	7	at	at	ADP
bjos-8661512	158	8	2	2	NUM
bjos-8661512	158	9	,	,	PUNCT
bjos-8661512	158	10	4	4	NUM
bjos-8661512	158	11	,	,	PUNCT
bjos-8661512	158	12	8	8	NUM
bjos-8661512	158	13	and	and	CCONJ
bjos-8661512	158	14	128	128	NUM
bjos-8661512	158	15	μg.ml-1	μg.ml-1	ADV
bjos-8661512	158	16	,	,	PUNCT
bjos-8661512	158	17	with	with	ADP
bjos-8661512	158	18	the	the	DET
bjos-8661512	158	19	lowest	low	ADJ
bjos-8661512	158	20	number	number	NOUN
bjos-8661512	158	21	of	of	ADP
bjos-8661512	158	22	osteoclast	osteoclast	ADJ
bjos-8661512	158	23	-	-	PUNCT
bjos-8661512	158	24	like	like	ADJ
bjos-8661512	158	25	cells	cell	NOUN
bjos-8661512	158	26	in	in	ADP
bjos-8661512	158	27	2	2	NUM
bjos-8661512	158	28	and	and	CCONJ
bjos-8661512	158	29	4	4	NUM
bjos-8661512	158	30	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	158	31	(	(	PUNCT
bjos-8661512	158	32	p<0.05	p<0.05	NOUN
bjos-8661512	158	33	)	)	PUNCT
bjos-8661512	158	34	.	.	PUNCT
bjos-8661512	159	1	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	159	2	was	be	AUX
bjos-8661512	159	3	most	most	ADV
bjos-8661512	159	4	effective	effective	ADJ
bjos-8661512	159	5	in	in	ADP
bjos-8661512	159	6	reducing	reduce	VERB
bjos-8661512	159	7	osteoclast	osteoclast	ADJ
bjos-8661512	159	8	-	-	PUNCT
bjos-8661512	159	9	like	like	ADJ
bjos-8661512	159	10	cells	cell	NOUN
bjos-8661512	159	11	at	at	ADP
bjos-8661512	159	12	8	8	NUM
bjos-8661512	159	13	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	159	14	(	(	PUNCT
bjos-8661512	159	15	p<0.05	p<0.05	NOUN
bjos-8661512	159	16	)	)	PUNCT
bjos-8661512	159	17	.	.	PUNCT
bjos-8661512	160	1	however	however	ADV
bjos-8661512	160	2	,	,	PUNCT
bjos-8661512	160	3	2	2	NUM
bjos-8661512	160	4	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	160	5	of	of	ADP
bjos-8661512	160	6	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	160	7	showed	show	VERB
bjos-8661512	160	8	the	the	DET
bjos-8661512	160	9	highest	high	ADJ
bjos-8661512	160	10	number	number	NOUN
bjos-8661512	160	11	of	of	ADP
bjos-8661512	160	12	differentiated	differentiated	ADJ
bjos-8661512	160	13	osteoclast	osteoclast	ADJ
bjos-8661512	160	14	-	-	PUNCT
bjos-8661512	160	15	like	like	ADJ
bjos-8661512	160	16	cells	cell	NOUN
bjos-8661512	160	17	(	(	PUNCT
bjos-8661512	160	18	p	p	X
bjos-8661512	160	19	<	<	X
bjos-8661512	160	20	0.05	0.05	NUM
bjos-8661512	160	21	)	)	PUNCT
bjos-8661512	160	22	.	.	PUNCT
bjos-8661512	161	1	meanwhile	meanwhile	ADV
bjos-8661512	161	2	,	,	PUNCT
bjos-8661512	161	3	doxycycline	doxycycline	PROPN
bjos-8661512	161	4	exhibited	exhibit	VERB
bjos-8661512	161	5	a	a	DET
bjos-8661512	161	6	gradual	gradual	ADJ
bjos-8661512	161	7	reduction	reduction	NOUN
bjos-8661512	161	8	in	in	ADP
bjos-8661512	161	9	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	161	10	,	,	PUNCT
bjos-8661512	161	11	and	and	CCONJ
bjos-8661512	161	12	128	128	NUM
bjos-8661512	161	13	μg.ml-1	μg.ml-1	ADJ
bjos-8661512	161	14	stimulated	stimulated	ADJ
bjos-8661512	161	15	cells	cell	NOUN
bjos-8661512	161	16	demonstrated	demonstrate	VERB
bjos-8661512	161	17	the	the	DET
bjos-8661512	161	18	lowest	low	ADJ
bjos-8661512	161	19	number	number	NOUN
bjos-8661512	161	20	of	of	ADP
bjos-8661512	161	21	differentiated	differentiated	ADJ
bjos-8661512	161	22	osteoclast	osteoclast	ADJ
bjos-8661512	161	23	-	-	PUNCT
bjos-8661512	161	24	like	like	ADJ
bjos-8661512	161	25	cells	cell	NOUN
bjos-8661512	161	26	.	.	PUNCT
bjos-8661512	162	1	based	base	VERB
bjos-8661512	162	2	on	on	ADP
bjos-8661512	162	3	the	the	DET
bjos-8661512	162	4	number	number	NOUN
bjos-8661512	162	5	of	of	ADP
bjos-8661512	162	6	osteoclast	osteoclast	ADJ
bjos-8661512	162	7	-	-	PUNCT
bjos-8661512	162	8	like	like	ADJ
bjos-8661512	162	9	cells	cell	NOUN
bjos-8661512	162	10	differentiated	differentiate	VERB
bjos-8661512	162	11	by	by	ADP
bjos-8661512	162	12	rrankl	rrankl	NOUN
bjos-8661512	162	13	-	-	PUNCT
bjos-8661512	162	14	stimulated	stimulate	VERB
bjos-8661512	162	15	raw	raw	ADJ
bjos-8661512	162	16	cell	cell	NOUN
bjos-8661512	162	17	culture	culture	NOUN
bjos-8661512	162	18	,	,	PUNCT
bjos-8661512	162	19	the	the	DET
bjos-8661512	162	20	concentration	concentration	NOUN
bjos-8661512	162	21	of	of	ADP
bjos-8661512	162	22	8	8	NUM
bjos-8661512	162	23	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	162	24	was	be	AUX
bjos-8661512	162	25	the	the	DET
bjos-8661512	162	26	lowest	low	ADJ
bjos-8661512	162	27	common	common	ADJ
bjos-8661512	162	28	concentration	concentration	NOUN
bjos-8661512	162	29	for	for	ADP
bjos-8661512	162	30	hdps	hdps	ADJ
bjos-8661512	162	31	,	,	PUNCT
bjos-8661512	162	32	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	162	33	,	,	PUNCT
bjos-8661512	162	34	and	and	CCONJ
bjos-8661512	162	35	doxycycline	doxycycline	NOUN
bjos-8661512	162	36	,	,	PUNCT
bjos-8661512	162	37	capable	capable	ADJ
bjos-8661512	162	38	of	of	ADP
bjos-8661512	162	39	reducing	reduce	VERB
bjos-8661512	162	40	differentiation	differentiation	NOUN
bjos-8661512	162	41	in	in	ADP
bjos-8661512	162	42	osteoclast	osteoclast	ADJ
bjos-8661512	162	43	-	-	PUNCT
bjos-8661512	162	44	like	like	ADJ
bjos-8661512	162	45	cells	cell	NOUN
bjos-8661512	162	46	.	.	PUNCT
bjos-8661512	163	1	therefore	therefore	ADV
bjos-8661512	163	2	,	,	PUNCT
bjos-8661512	163	3	the	the	DET
bjos-8661512	163	4	best	good	ADJ
bjos-8661512	163	5	results	result	NOUN
bjos-8661512	163	6	were	be	AUX
bjos-8661512	163	7	exhibited	exhibit	VERB
bjos-8661512	163	8	by	by	ADP
bjos-8661512	163	9	ll-37	ll-37	NOUN
bjos-8661512	163	10	and	and	CCONJ
bjos-8661512	163	11	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	163	12	.	.	PUNCT
bjos-8661512	164	1	ll-37	ll-37	NOUN
bjos-8661512	164	2	showed	show	VERB
bjos-8661512	164	3	approximately	approximately	ADV
bjos-8661512	164	4	67	67	NUM
bjos-8661512	164	5	%	%	NOUN
bjos-8661512	164	6	fewer	few	ADJ
bjos-8661512	164	7	osteoclasts	osteoclast	NOUN
bjos-8661512	164	8	than	than	SCONJ
bjos-8661512	164	9	clavanin	clavanin	PROPN
bjos-8661512	164	10	a	a	PRON
bjos-8661512	164	11	,	,	PUNCT
bjos-8661512	164	12	clavanin	clavanin	PROPN
bjos-8661512	164	13	mo	mo	PROPN
bjos-8661512	164	14	and	and	CCONJ
bjos-8661512	164	15	doxycycline	doxycycline	NOUN
bjos-8661512	164	16	,	,	PUNCT
bjos-8661512	164	17	while	while	SCONJ
bjos-8661512	164	18	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	164	19	showed	show	VERB
bjos-8661512	164	20	59	59	NUM
bjos-8661512	164	21	%	%	NOUN
bjos-8661512	164	22	fewer	few	ADJ
bjos-8661512	164	23	osteoclasts	osteoclast	NOUN
bjos-8661512	164	24	compared	compare	VERB
bjos-8661512	164	25	to	to	ADP
bjos-8661512	164	26	clavanins	clavanin	NOUN
bjos-8661512	164	27	and	and	CCONJ
bjos-8661512	164	28	doxycycline	doxycycline	NOUN
bjos-8661512	164	29	.	.	PUNCT
bjos-8661512	165	1	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	165	2	and	and	CCONJ
bjos-8661512	165	3	ll-37	ll-37	NOUN
bjos-8661512	165	4	demonstrated	demonstrate	VERB
bjos-8661512	165	5	better	well	ADJ
bjos-8661512	165	6	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	165	7	downregulation	downregulation	NOUN
bjos-8661512	165	8	,	,	PUNCT
bjos-8661512	165	9	compared	compare	VERB
bjos-8661512	165	10	to	to	ADP
bjos-8661512	165	11	the	the	DET
bjos-8661512	165	12	same	same	ADJ
bjos-8661512	165	13	concentration	concentration	NOUN
bjos-8661512	165	14	of	of	ADP
bjos-8661512	165	15	clavanin	clavanin	NOUN
bjos-8661512	165	16	a	a	PRON
bjos-8661512	165	17	,	,	PUNCT
bjos-8661512	165	18	clavanin	clavanin	PROPN
bjos-8661512	165	19	mo	mo	PROPN
bjos-8661512	165	20	and	and	CCONJ
bjos-8661512	165	21	doxycycline	doxycycline	NOUN
bjos-8661512	165	22	(	(	PUNCT
bjos-8661512	165	23	p<0.0001	p<0.0001	NOUN
bjos-8661512	165	24	)	)	PUNCT
bjos-8661512	165	25	.	.	PUNCT
bjos-8661512	166	1	therefore	therefore	ADV
bjos-8661512	166	2	,	,	PUNCT
bjos-8661512	166	3	among	among	ADP
bjos-8661512	166	4	the	the	DET
bjos-8661512	166	5	tested	test	VERB
bjos-8661512	166	6	hdps	hdps	NOUN
bjos-8661512	166	7	,	,	PUNCT
bjos-8661512	166	8	ll-37	ll-37	NOUN
bjos-8661512	166	9	presented	present	VERB
bjos-8661512	166	10	the	the	DET
bjos-8661512	166	11	best	good	ADJ
bjos-8661512	166	12	ability	ability	NOUN
bjos-8661512	166	13	to	to	PART
bjos-8661512	166	14	reduce	reduce	VERB
bjos-8661512	166	15	the	the	DET
bjos-8661512	166	16	number	number	NOUN
bjos-8661512	166	17	of	of	ADP
bjos-8661512	166	18	osteoclasts	osteoclast	NOUN
bjos-8661512	166	19	in	in	ADP
bjos-8661512	166	20	vitro	vitro	X
bjos-8661512	166	21	(	(	PUNCT
bjos-8661512	166	22	p<0.05	p<0.05	NOUN
bjos-8661512	166	23	)	)	PUNCT
bjos-8661512	166	24	.	.	PUNCT
bjos-8661512	167	1	8	8	NUM
bjos-8661512	167	2	amorim	amorim	VERB
bjos-8661512	167	3	et	et	PROPN
bjos-8661512	167	4	al	al	PROPN
bjos-8661512	167	5	.	.	PROPN
bjos-8661512	167	6	figure	figure	NOUN
bjos-8661512	167	7	3	3	NUM
bjos-8661512	167	8	.	.	PUNCT
bjos-8661512	167	9	representative	representative	ADJ
bjos-8661512	167	10	photos	photo	NOUN
bjos-8661512	167	11	of	of	ADP
bjos-8661512	167	12	trap	trap	NOUN
bjos-8661512	167	13	positive	positive	ADJ
bjos-8661512	167	14	stained	stained	ADJ
bjos-8661512	167	15	cells	cell	NOUN
bjos-8661512	167	16	(	(	PUNCT
bjos-8661512	167	17	a	a	NOUN
bjos-8661512	167	18	)	)	PUNCT
bjos-8661512	167	19	and	and	CCONJ
bjos-8661512	167	20	number	number	NOUN
bjos-8661512	167	21	of	of	ADP
bjos-8661512	167	22	multinucleated	multinucleate	VERB
bjos-8661512	167	23	osteoclastlike	osteoclastlike	NOUN
bjos-8661512	167	24	cells	cell	NOUN
bjos-8661512	167	25	(	(	PUNCT
bjos-8661512	167	26	b	b	NOUN
bjos-8661512	167	27	)	)	PUNCT
bjos-8661512	167	28	induced	induce	VERB
bjos-8661512	167	29	by	by	ADP
bjos-8661512	167	30	2.5x103	2.5x103	ADJ
bjos-8661512	167	31	raw	raw	ADJ
bjos-8661512	167	32	cell	cell	NOUN
bjos-8661512	167	33	and	and	CCONJ
bjos-8661512	167	34	2.5x103	2.5x103	ADJ
bjos-8661512	167	35	raw	raw	ADJ
bjos-8661512	167	36	cells	cell	NOUN
bjos-8661512	167	37	stimulated	stimulate	VERB
bjos-8661512	167	38	with	with	ADP
bjos-8661512	167	39	100	100	NUM
bjos-8661512	167	40	ng.ml-1	ng.ml-1	ADJ
bjos-8661512	167	41	rrankl	rrankl	NOUN
bjos-8661512	167	42	(	(	PUNCT
bjos-8661512	167	43	control	control	NOUN
bjos-8661512	167	44	)	)	PUNCT
bjos-8661512	167	45	.	.	PUNCT
bjos-8661512	168	1	cultures	culture	NOUN
bjos-8661512	168	2	were	be	AUX
bjos-8661512	168	3	rrankl	rrankl	NOUN
bjos-8661512	168	4	-	-	PUNCT
bjos-8661512	168	5	stimulated	stimulate	VERB
bjos-8661512	168	6	and	and	CCONJ
bjos-8661512	168	7	tested	test	VERB
bjos-8661512	168	8	with	with	ADP
bjos-8661512	168	9	2	2	NUM
bjos-8661512	168	10	,	,	PUNCT
bjos-8661512	168	11	8	8	NUM
bjos-8661512	168	12	,	,	PUNCT
bjos-8661512	168	13	32	32	NUM
bjos-8661512	168	14	,	,	PUNCT
bjos-8661512	168	15	and	and	CCONJ
bjos-8661512	168	16	128	128	NUM
bjos-8661512	168	17	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	168	18	of	of	ADP
bjos-8661512	168	19	clavanin	clavanin	NOUN
bjos-8661512	168	20	a	a	PRON
bjos-8661512	168	21	,	,	PUNCT
bjos-8661512	168	22	clavanin	clavanin	PROPN
bjos-8661512	168	23	mo	mo	PROPN
bjos-8661512	168	24	,	,	PUNCT
bjos-8661512	168	25	ll-37	ll-37	PROPN
bjos-8661512	168	26	,	,	PUNCT
bjos-8661512	168	27	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	168	28	and	and	CCONJ
bjos-8661512	168	29	doxycycline	doxycycline	NOUN
bjos-8661512	168	30	,	,	PUNCT
bjos-8661512	168	31	after	after	ADP
bjos-8661512	168	32	7	7	NUM
bjos-8661512	168	33	days	day	NOUN
bjos-8661512	168	34	.	.	PUNCT
bjos-8661512	169	1	scale	scale	NOUN
bjos-8661512	169	2	bar	bar	NOUN
bjos-8661512	169	3	:	:	PUNCT
bjos-8661512	169	4	50	50	NUM
bjos-8661512	169	5	μm	μm	NOUN
bjos-8661512	169	6	.	.	PUNCT
bjos-8661512	170	1	each	each	PRON
bjos-8661512	170	2	well	well	INTJ
bjos-8661512	170	3	was	be	AUX
bjos-8661512	170	4	completely	completely	ADV
bjos-8661512	170	5	checked	check	VERB
bjos-8661512	170	6	,	,	PUNCT
bjos-8661512	170	7	and	and	CCONJ
bjos-8661512	170	8	osteoclasts	osteoclast	NOUN
bjos-8661512	170	9	were	be	AUX
bjos-8661512	170	10	counted	count	VERB
bjos-8661512	170	11	at	at	ADP
bjos-8661512	170	12	20x	20x	NOUN
bjos-8661512	170	13	magnification	magnification	NOUN
bjos-8661512	170	14	.	.	PUNCT
bjos-8661512	171	1	black	black	ADJ
bjos-8661512	171	2	arrows	arrow	NOUN
bjos-8661512	171	3	show	show	VERB
bjos-8661512	171	4	osteoclast	osteoclast	ADJ
bjos-8661512	171	5	-	-	PUNCT
bjos-8661512	171	6	like	like	ADJ
bjos-8661512	171	7	cells	cell	NOUN
bjos-8661512	171	8	with	with	ADP
bjos-8661512	171	9	more	more	ADJ
bjos-8661512	171	10	than	than	ADP
bjos-8661512	171	11	3	3	NUM
bjos-8661512	171	12	nuclei	nucleus	NOUN
bjos-8661512	171	13	.	.	PUNCT
bjos-8661512	172	1	statistical	statistical	ADJ
bjos-8661512	172	2	differences	difference	NOUN
bjos-8661512	172	3	by	by	ADP
bjos-8661512	172	4	one	one	NUM
bjos-8661512	172	5	-	-	PUNCT
bjos-8661512	172	6	way	way	NOUN
bjos-8661512	172	7	anova	anova	PROPN
bjos-8661512	172	8	test	test	NOUN
bjos-8661512	172	9	and	and	CCONJ
bjos-8661512	172	10	tukey	tukey	PROPN
bjos-8661512	172	11	’s	’s	PART
bjos-8661512	172	12	post	post	X
bjos-8661512	172	13	hoc	hoc	X
bjos-8661512	172	14	were	be	AUX
bjos-8661512	172	15	represented	represent	VERB
bjos-8661512	172	16	by	by	ADP
bjos-8661512	172	17	*	*	PUNCT
bjos-8661512	172	18	p<0.001	p<0.001	PROPN
bjos-8661512	172	19	compared	compare	VERB
bjos-8661512	172	20	to	to	PART
bjos-8661512	172	21	control	control	VERB
bjos-8661512	172	22	in	in	ADP
bjos-8661512	172	23	each	each	DET
bjos-8661512	172	24	tested	test	VERB
bjos-8661512	172	25	condition	condition	NOUN
bjos-8661512	172	26	.	.	PUNCT
bjos-8661512	173	1	statistical	statistical	ADJ
bjos-8661512	173	2	differences	difference	NOUN
bjos-8661512	173	3	of	of	ADP
bjos-8661512	173	4	comparative	comparative	ADJ
bjos-8661512	173	5	analysis	analysis	NOUN
bjos-8661512	173	6	of	of	ADP
bjos-8661512	173	7	the	the	DET
bjos-8661512	173	8	lowest	low	ADJ
bjos-8661512	173	9	common	common	ADJ
bjos-8661512	173	10	concentration	concentration	NOUN
bjos-8661512	173	11	,	,	PUNCT
bjos-8661512	173	12	with	with	ADP
bjos-8661512	173	13	greater	great	ADJ
bjos-8661512	173	14	reduction	reduction	NOUN
bjos-8661512	173	15	in	in	ADP
bjos-8661512	173	16	osteoclast	osteoclast	ADJ
bjos-8661512	173	17	-	-	PUNCT
bjos-8661512	173	18	like	like	ADJ
bjos-8661512	173	19	cell	cell	NOUN
bjos-8661512	173	20	differentiation	differentiation	NOUN
bjos-8661512	173	21	,	,	PUNCT
bjos-8661512	173	22	of	of	ADP
bjos-8661512	173	23	all	all	DET
bjos-8661512	173	24	tested	test	VERB
bjos-8661512	173	25	materials	material	NOUN
bjos-8661512	173	26	:	:	PUNCT
bjos-8661512	173	27	8μg.ml-1	8μg.ml-1	NUM
bjos-8661512	173	28	of	of	ADP
bjos-8661512	173	29	clavanin	clavanin	PROPN
bjos-8661512	173	30	a	a	PRON
bjos-8661512	173	31	,	,	PUNCT
bjos-8661512	173	32	clavanin	clavanin	PROPN
bjos-8661512	173	33	mo	mo	PROPN
bjos-8661512	173	34	,	,	PUNCT
bjos-8661512	173	35	ll-37	ll-37	PROPN
bjos-8661512	173	36	,	,	PUNCT
bjos-8661512	173	37	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	173	38	and	and	CCONJ
bjos-8661512	173	39	doxycycline	doxycycline	NOUN
bjos-8661512	173	40	(	(	PUNCT
bjos-8661512	173	41	samples	sample	NOUN
bjos-8661512	173	42	at	at	ADP
bjos-8661512	173	43	8μg.ml-1	8μg.ml-1	NUM
bjos-8661512	173	44	)	)	PUNCT
bjos-8661512	173	45	were	be	AUX
bjos-8661512	173	46	represented	represent	VERB
bjos-8661512	173	47	by	by	ADP
bjos-8661512	173	48	*	*	PROPN
bjos-8661512	173	49	p<0.0001	p<0.0001	NOUN
bjos-8661512	173	50	.	.	PUNCT
bjos-8661512	174	1	number	number	NOUN
bjos-8661512	174	2	of	of	ADP
bjos-8661512	174	3	osteoclast	osteoclast	ADJ
bjos-8661512	174	4	-	-	PUNCT
bjos-8661512	174	5	like	like	ADJ
bjos-8661512	174	6	cells	cell	NOUN
bjos-8661512	174	7	was	be	AUX
bjos-8661512	174	8	represented	represent	VERB
bjos-8661512	174	9	as	as	ADP
bjos-8661512	174	10	the	the	DET
bjos-8661512	174	11	standard	standard	ADJ
bjos-8661512	174	12	error	error	NOUN
bjos-8661512	174	13	of	of	ADP
bjos-8661512	174	14	the	the	DET
bjos-8661512	174	15	mean	mean	NOUN
bjos-8661512	174	16	.	.	PUNCT
bjos-8661512	175	1	all	all	DET
bjos-8661512	175	2	experiments	experiment	NOUN
bjos-8661512	175	3	were	be	AUX
bjos-8661512	175	4	done	do	VERB
bjos-8661512	175	5	in	in	ADP
bjos-8661512	175	6	technical	technical	ADJ
bjos-8661512	175	7	and	and	CCONJ
bjos-8661512	175	8	biological	biological	ADJ
bjos-8661512	175	9	triplicates	triplicate	NOUN
bjos-8661512	175	10	.	.	PUNCT
bjos-8661512	176	1	o	o	X
bjos-8661512	176	2	st	st	PROPN
bjos-8661512	176	3	eo	eo	PROPN
bjos-8661512	176	4	cl	cl	PROPN
bjos-8661512	176	5	as	as	ADP
bjos-8661512	176	6	ts	ts	ADP
bjos-8661512	176	7	clavanin	clavanin	PROPN
bjos-8661512	176	8	ab	ab	PROPN
bjos-8661512	176	9	a	a	DET
bjos-8661512	176	10	50	50	NUM
bjos-8661512	176	11	40	40	NUM
bjos-8661512	176	12	30	30	NUM
bjos-8661512	176	13	20	20	NUM
bjos-8661512	176	14	10	10	NUM
bjos-8661512	176	15	0	0	NUM
bjos-8661512	176	16	contro	contro	PROPN
bjos-8661512	176	17	l	l	PROPN
bjos-8661512	176	18	2	2	NUM
bjos-8661512	176	19	μg.m	μg.m	NOUN
bjos-8661512	176	20	l1	l1	PROPN
bjos-8661512	176	21	8	8	NUM
bjos-8661512	176	22	μg.m	μg.m	PROPN
bjos-8661512	176	23	l1	l1	PROPN
bjos-8661512	176	24	32	32	NUM
bjos-8661512	176	25	μg.m	μg.m	PROPN
bjos-8661512	176	26	l1	l1	PROPN
bjos-8661512	176	27	128	128	NUM
bjos-8661512	176	28	μg.m	μg.m	PROPN
bjos-8661512	176	29	l1	l1	PROPN
bjos-8661512	176	30	*	*	PUNCT
bjos-8661512	177	1	*	*	PUNCT
bjos-8661512	178	1	*	*	PUNCT
bjos-8661512	178	2	*	*	PUNCT
bjos-8661512	178	3	o	o	X
bjos-8661512	178	4	st	st	X
bjos-8661512	178	5	eo	eo	PROPN
bjos-8661512	178	6	cl	cl	PROPN
bjos-8661512	178	7	as	as	ADP
bjos-8661512	178	8	ts	ts	ADP
bjos-8661512	178	9	clavanin	clavanin	PROPN
bjos-8661512	178	10	mo	mo	PROPN
bjos-8661512	178	11	50	50	NUM
bjos-8661512	178	12	40	40	NUM
bjos-8661512	178	13	30	30	NUM
bjos-8661512	178	14	20	20	NUM
bjos-8661512	178	15	10	10	NUM
bjos-8661512	178	16	0	0	NUM
bjos-8661512	178	17	contro	contro	PROPN
bjos-8661512	178	18	l	l	PROPN
bjos-8661512	178	19	2	2	NUM
bjos-8661512	178	20	μg.m	μg.m	NOUN
bjos-8661512	178	21	l1	l1	PROPN
bjos-8661512	178	22	8	8	NUM
bjos-8661512	178	23	μg.m	μg.m	PROPN
bjos-8661512	178	24	l1	l1	PROPN
bjos-8661512	178	25	32	32	NUM
bjos-8661512	178	26	μg.m	μg.m	PROPN
bjos-8661512	178	27	l1	l1	PROPN
bjos-8661512	178	28	128	128	NUM
bjos-8661512	178	29	μg.m	μg.m	PROPN
bjos-8661512	178	30	l1	l1	PROPN
bjos-8661512	178	31	*	*	PUNCT
bjos-8661512	179	1	*	*	PUNCT
bjos-8661512	180	1	*	*	PUNCT
bjos-8661512	180	2	*	*	PUNCT
bjos-8661512	180	3	o	o	X
bjos-8661512	180	4	st	st	X
bjos-8661512	180	5	eo	eo	PROPN
bjos-8661512	180	6	cl	cl	PROPN
bjos-8661512	180	7	as	as	ADP
bjos-8661512	180	8	ts	ts	ADP
bjos-8661512	180	9	ll-37	ll-37	PROPN
bjos-8661512	180	10	clavanin	clavanin	NOUN
bjos-8661512	180	11	acontrol	acontrol	NOUN
bjos-8661512	180	12	2	2	NUM
bjos-8661512	180	13	μg	μg	PROPN
bjos-8661512	180	14	.m	.m	PROPN
bjos-8661512	180	15	l-1	l-1	NUM
bjos-8661512	181	1	8	8	NUM
bjos-8661512	181	2	μg	μg	PROPN
bjos-8661512	181	3	.m	.m	PROPN
bjos-8661512	182	1	l-1	l-1	PROPN
bjos-8661512	183	1	ra	ra	PROPN
bjos-8661512	184	1	w	w	PROPN
bjos-8661512	184	2	c	c	PROPN
bjos-8661512	184	3	el	el	PROPN
bjos-8661512	184	4	ls	ls	INTJ
bjos-8661512	184	5	ra	ra	PROPN
bjos-8661512	184	6	w	w	PROPN
bjos-8661512	184	7	c	c	PROPN
bjos-8661512	184	8	el	el	PROPN
bjos-8661512	184	9	ls	ls	PROPN
bjos-8661512	185	1	+	+	CCONJ
bjos-8661512	185	2	rr	rr	VERB
bjos-8661512	185	3	an	an	DET
bjos-8661512	185	4	kl	kl	PROPN
bjos-8661512	185	5	32	32	NUM
bjos-8661512	185	6	μ	μ	PROPN
bjos-8661512	185	7	g.	g.	PROPN
bjos-8661512	185	8	m	m	PROPN
bjos-8661512	185	9	l-1	l-1	NOUN
bjos-8661512	185	10	12	12	NUM
bjos-8661512	185	11	8	8	NUM
bjos-8661512	185	12	μg	μg	PROPN
bjos-8661512	185	13	.m	.m	PROPN
bjos-8661512	185	14	l-1	l-1	PROPN
bjos-8661512	186	1	clavanin	clavanin	PROPN
bjos-8661512	186	2	mo	mo	PROPN
bjos-8661512	186	3	ll-37	ll-37	PROPN
bjos-8661512	186	4	50	50	NUM
bjos-8661512	186	5	40	40	NUM
bjos-8661512	186	6	30	30	NUM
bjos-8661512	186	7	20	20	NUM
bjos-8661512	186	8	10	10	NUM
bjos-8661512	186	9	0	0	NUM
bjos-8661512	186	10	contro	contro	PROPN
bjos-8661512	186	11	l	l	PROPN
bjos-8661512	186	12	2	2	NUM
bjos-8661512	186	13	μg.m	μg.m	NOUN
bjos-8661512	186	14	l1	l1	PROPN
bjos-8661512	186	15	8	8	NUM
bjos-8661512	186	16	μg.m	μg.m	PROPN
bjos-8661512	186	17	l1	l1	PROPN
bjos-8661512	186	18	32	32	NUM
bjos-8661512	186	19	μg.m	μg.m	PROPN
bjos-8661512	186	20	l1	l1	PROPN
bjos-8661512	186	21	128	128	NUM
bjos-8661512	186	22	μg.m	μg.m	PROPN
bjos-8661512	186	23	l1	l1	PROPN
bjos-8661512	186	24	*	*	PUNCT
bjos-8661512	187	1	*	*	PUNCT
bjos-8661512	188	1	*	*	PUNCT
bjos-8661512	188	2	*	*	PUNCT
bjos-8661512	188	3	o	o	X
bjos-8661512	188	4	st	st	X
bjos-8661512	188	5	eo	eo	PROPN
bjos-8661512	188	6	cl	cl	PROPN
bjos-8661512	188	7	as	as	ADP
bjos-8661512	188	8	ts	ts	ADP
bjos-8661512	188	9	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	188	10	50	50	NUM
bjos-8661512	188	11	40	40	NUM
bjos-8661512	188	12	30	30	NUM
bjos-8661512	188	13	20	20	NUM
bjos-8661512	188	14	10	10	NUM
bjos-8661512	188	15	0	0	NUM
bjos-8661512	188	16	contro	contro	PROPN
bjos-8661512	188	17	l	l	PROPN
bjos-8661512	188	18	2	2	NUM
bjos-8661512	188	19	μg.m	μg.m	NOUN
bjos-8661512	188	20	l1	l1	PROPN
bjos-8661512	188	21	8	8	NUM
bjos-8661512	188	22	μg.m	μg.m	PROPN
bjos-8661512	188	23	l1	l1	PROPN
bjos-8661512	188	24	32	32	NUM
bjos-8661512	188	25	μg.m	μg.m	PROPN
bjos-8661512	188	26	l1	l1	PROPN
bjos-8661512	188	27	128	128	NUM
bjos-8661512	188	28	μg.m	μg.m	PROPN
bjos-8661512	188	29	l1	l1	PROPN
bjos-8661512	188	30	*	*	PUNCT
bjos-8661512	189	1	*	*	PUNCT
bjos-8661512	190	1	*	*	PUNCT
bjos-8661512	190	2	*	*	PUNCT
bjos-8661512	190	3	o	o	X
bjos-8661512	190	4	st	st	X
bjos-8661512	190	5	eo	eo	PROPN
bjos-8661512	190	6	cl	cl	PROPN
bjos-8661512	190	7	as	as	ADP
bjos-8661512	190	8	ts	ts	ADP
bjos-8661512	190	9	doxycycline	doxycycline	NOUN
bjos-8661512	190	10	50	50	NUM
bjos-8661512	190	11	40	40	NUM
bjos-8661512	190	12	30	30	NUM
bjos-8661512	190	13	20	20	NUM
bjos-8661512	190	14	10	10	NUM
bjos-8661512	190	15	0	0	NUM
bjos-8661512	190	16	contro	contro	PROPN
bjos-8661512	190	17	l	l	PROPN
bjos-8661512	190	18	2	2	NUM
bjos-8661512	190	19	μg.m	μg.m	NOUN
bjos-8661512	190	20	l1	l1	PROPN
bjos-8661512	190	21	8	8	NUM
bjos-8661512	190	22	μg.m	μg.m	PROPN
bjos-8661512	190	23	l1	l1	PROPN
bjos-8661512	190	24	32	32	NUM
bjos-8661512	190	25	μg.m	μg.m	PROPN
bjos-8661512	190	26	l1	l1	PROPN
bjos-8661512	190	27	128	128	NUM
bjos-8661512	190	28	μg.m	μg.m	PROPN
bjos-8661512	190	29	l1	l1	PROPN
bjos-8661512	190	30	*	*	PUNCT
bjos-8661512	191	1	*	*	PUNCT
bjos-8661512	192	1	*	*	PUNCT
bjos-8661512	192	2	*	*	PUNCT
bjos-8661512	192	3	o	o	X
bjos-8661512	192	4	st	st	X
bjos-8661512	192	5	eo	eo	PROPN
bjos-8661512	192	6	cl	cl	PROPN
bjos-8661512	192	7	as	as	ADP
bjos-8661512	192	8	ts	ts	ADP
bjos-8661512	192	9	samples	sample	NOUN
bjos-8661512	192	10	at	at	ADP
bjos-8661512	192	11	8	8	NUM
bjos-8661512	192	12	μg.ml-1	μg.ml-1	ADP
bjos-8661512	192	13	50	50	NUM
bjos-8661512	192	14	40	40	NUM
bjos-8661512	192	15	30	30	NUM
bjos-8661512	192	16	20	20	NUM
bjos-8661512	192	17	10	10	NUM
bjos-8661512	192	18	0	0	NUM
bjos-8661512	192	19	clava	clava	NOUN
bjos-8661512	192	20	nin	nin	PROPN
bjos-8661512	192	21	a	a	DET
bjos-8661512	192	22	clava	clava	NOUN
bjos-8661512	193	1	nin	nin	NOUN
bjos-8661512	193	2	m	m	PROPN
bjos-8661512	193	3	o	o	PROPN
bjos-8661512	193	4	ll-37	ll-37	PROPN
bjos-8661512	193	5	ca(o	ca(o	PROPN
bjos-8661512	193	6	h	h	NOUN
bjos-8661512	193	7	)	)	PUNCT
bjos-8661512	193	8	2	2	NUM
bjos-8661512	193	9	doxy	doxy	PROPN
bjos-8661512	193	10	cy	cy	PROPN
bjos-8661512	193	11	cli	cli	PROPN
bjos-8661512	193	12	ne	ne	PROPN
bjos-8661512	193	13	*	*	PUNCT
bjos-8661512	193	14	*	*	PUNCT
bjos-8661512	193	15	*	*	PUNCT
bjos-8661512	194	1	*	*	PUNCT
bjos-8661512	194	2	*	*	PUNCT
bjos-8661512	194	3	*	*	PUNCT
bjos-8661512	194	4	*	*	PUNCT
bjos-8661512	194	5	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	194	6	doxycycline	doxycycline	VERB
bjos-8661512	194	7	9	9	NUM
bjos-8661512	194	8	amorim	amorim	NOUN
bjos-8661512	194	9	et	et	PROPN
bjos-8661512	194	10	al	al	PROPN
bjos-8661512	194	11	.	.	PROPN
bjos-8661512	194	12	discussion	discussion	NOUN
bjos-8661512	194	13	although	although	SCONJ
bjos-8661512	194	14	periodontal	periodontal	ADJ
bjos-8661512	194	15	and	and	CCONJ
bjos-8661512	194	16	endodontic	endodontic	ADJ
bjos-8661512	194	17	therapies	therapy	NOUN
bjos-8661512	194	18	are	be	AUX
bjos-8661512	194	19	highly	highly	ADV
bjos-8661512	194	20	effective	effective	ADJ
bjos-8661512	194	21	,	,	PUNCT
bjos-8661512	194	22	new	new	ADJ
bjos-8661512	194	23	substances	substance	NOUN
bjos-8661512	194	24	can	can	AUX
bjos-8661512	194	25	improve	improve	VERB
bjos-8661512	194	26	outcome	outcome	NOUN
bjos-8661512	194	27	expectations	expectation	NOUN
bjos-8661512	194	28	.	.	PUNCT
bjos-8661512	195	1	antimicrobial	antimicrobial	ADJ
bjos-8661512	195	2	,	,	PUNCT
bjos-8661512	195	3	immunomodulatory	immunomodulatory	ADJ
bjos-8661512	195	4	,	,	PUNCT
bjos-8661512	195	5	and	and	CCONJ
bjos-8661512	195	6	reparative	reparative	ADJ
bjos-8661512	195	7	activity	activity	NOUN
bjos-8661512	195	8	could	could	AUX
bjos-8661512	195	9	be	be	AUX
bjos-8661512	195	10	better	well	ADV
bjos-8661512	195	11	achieved	achieve	VERB
bjos-8661512	195	12	by	by	ADP
bjos-8661512	195	13	new	new	ADJ
bjos-8661512	195	14	therapies	therapy	NOUN
bjos-8661512	195	15	and	and	CCONJ
bjos-8661512	195	16	biologic	biologic	ADJ
bjos-8661512	195	17	substances19	substances19	NOUN
bjos-8661512	195	18	.	.	PUNCT
bjos-8661512	196	1	indeed	indeed	ADV
bjos-8661512	196	2	,	,	PUNCT
bjos-8661512	196	3	antimicrobial	antimicrobial	ADJ
bjos-8661512	196	4	resistance	resistance	NOUN
bjos-8661512	196	5	is	be	AUX
bjos-8661512	196	6	also	also	ADV
bjos-8661512	196	7	a	a	DET
bjos-8661512	196	8	current	current	ADJ
bjos-8661512	196	9	limitation	limitation	NOUN
bjos-8661512	196	10	for	for	ADP
bjos-8661512	196	11	both	both	DET
bjos-8661512	196	12	therapies6	therapies6	PROPN
bjos-8661512	196	13	.	.	PUNCT
bjos-8661512	197	1	the	the	DET
bjos-8661512	197	2	present	present	ADJ
bjos-8661512	197	3	study	study	NOUN
bjos-8661512	197	4	demonstrated	demonstrate	VERB
bjos-8661512	197	5	the	the	DET
bjos-8661512	197	6	in	in	ADV
bjos-8661512	197	7	vitro	vitro	X
bjos-8661512	197	8	potential	potential	NOUN
bjos-8661512	197	9	of	of	ADP
bjos-8661512	197	10	hdps	hdps	ADJ
bjos-8661512	197	11	clavanins	clavanin	NOUN
bjos-8661512	197	12	a	a	PRON
bjos-8661512	197	13	and	and	CCONJ
bjos-8661512	197	14	mo	mo	NOUN
bjos-8661512	197	15	in	in	ADP
bjos-8661512	197	16	an	an	DET
bjos-8661512	197	17	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	197	18	model	model	NOUN
bjos-8661512	197	19	.	.	PUNCT
bjos-8661512	198	1	results	result	NOUN
bjos-8661512	198	2	of	of	ADP
bjos-8661512	198	3	cellular	cellular	ADJ
bjos-8661512	198	4	no	no	DET
bjos-8661512	198	5	production	production	NOUN
bjos-8661512	198	6	,	,	PUNCT
bjos-8661512	198	7	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	198	8	,	,	PUNCT
bjos-8661512	198	9	and	and	CCONJ
bjos-8661512	198	10	the	the	DET
bjos-8661512	198	11	effects	effect	NOUN
bjos-8661512	198	12	of	of	ADP
bjos-8661512	198	13	hdps	hdps	NOUN
bjos-8661512	198	14	on	on	ADP
bjos-8661512	198	15	rrankl	rrankl	NOUN
bjos-8661512	198	16	-	-	PUNCT
bjos-8661512	198	17	mediated	mediate	VERB
bjos-8661512	198	18	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	198	19	were	be	AUX
bjos-8661512	198	20	compared	compare	VERB
bjos-8661512	198	21	to	to	ADP
bjos-8661512	198	22	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	198	23	and	and	CCONJ
bjos-8661512	198	24	doxycycline	doxycycline	NOUN
bjos-8661512	198	25	,	,	PUNCT
bjos-8661512	198	26	widely	widely	ADV
bjos-8661512	198	27	used	use	VERB
bjos-8661512	198	28	medications	medication	NOUN
bjos-8661512	198	29	in	in	ADP
bjos-8661512	198	30	endodontic6	endodontic6	NOUN
bjos-8661512	198	31	and	and	CCONJ
bjos-8661512	198	32	periodontal5	periodontal5	ADJ
bjos-8661512	198	33	areas	area	NOUN
bjos-8661512	198	34	,	,	PUNCT
bjos-8661512	198	35	respectively	respectively	ADV
bjos-8661512	198	36	.	.	PUNCT
bjos-8661512	199	1	study	study	NOUN
bjos-8661512	199	2	related	relate	VERB
bjos-8661512	199	3	to	to	ADP
bjos-8661512	199	4	clavanin	clavanin	NOUN
bjos-8661512	199	5	a	a	PRON
bjos-8661512	199	6	has	have	AUX
bjos-8661512	199	7	demonstrated	demonstrate	VERB
bjos-8661512	199	8	different	different	ADJ
bjos-8661512	199	9	activities	activity	NOUN
bjos-8661512	199	10	regarding	regard	VERB
bjos-8661512	199	11	this	this	DET
bjos-8661512	199	12	peptide	peptide	NOUN
bjos-8661512	199	13	,	,	PUNCT
bjos-8661512	199	14	including	include	VERB
bjos-8661512	199	15	important	important	ADJ
bjos-8661512	199	16	points	point	NOUN
bjos-8661512	199	17	for	for	ADP
bjos-8661512	199	18	dentistry	dentistry	NOUN
bjos-8661512	199	19	,	,	PUNCT
bjos-8661512	199	20	such	such	ADJ
bjos-8661512	199	21	as	as	ADP
bjos-8661512	199	22	antibiofilm	antibiofilm	NOUN
bjos-8661512	199	23	and	and	CCONJ
bjos-8661512	199	24	antimicrobial	antimicrobial	ADJ
bjos-8661512	199	25	activity	activity	NOUN
bjos-8661512	199	26	.	.	PUNCT
bjos-8661512	200	1	hdp	hdp	PROPN
bjos-8661512	200	2	clavanin	clavanin	PROPN
bjos-8661512	200	3	a	a	DET
bjos-8661512	200	4	showed	show	VERB
bjos-8661512	200	5	antibiofilm	antibiofilm	NOUN
bjos-8661512	200	6	activity	activity	NOUN
bjos-8661512	200	7	against	against	ADP
bjos-8661512	200	8	fungal	fungal	ADJ
bjos-8661512	200	9	biofilms	biofilm	NOUN
bjos-8661512	200	10	when	when	SCONJ
bjos-8661512	200	11	used	use	VERB
bjos-8661512	200	12	to	to	PART
bjos-8661512	200	13	coat	coat	VERB
bjos-8661512	200	14	an	an	DET
bjos-8661512	200	15	amniotic	amniotic	ADJ
bjos-8661512	200	16	membrane	membrane	NOUN
bjos-8661512	200	17	,	,	PUNCT
bjos-8661512	200	18	which	which	PRON
bjos-8661512	200	19	is	be	AUX
bjos-8661512	200	20	frequently	frequently	ADV
bjos-8661512	200	21	used	use	VERB
bjos-8661512	200	22	in	in	ADP
bjos-8661512	200	23	ophthalmologic	ophthalmologic	ADJ
bjos-8661512	200	24	surgery	surgery	NOUN
bjos-8661512	200	25	for	for	ADP
bjos-8661512	200	26	rapid	rapid	ADJ
bjos-8661512	200	27	ocular	ocular	ADJ
bjos-8661512	200	28	surface	surface	NOUN
bjos-8661512	200	29	reconstruction20	reconstruction20	NOUN
bjos-8661512	200	30	.	.	PUNCT
bjos-8661512	201	1	hdps	hdps	PROPN
bjos-8661512	201	2	clavanin	clavanin	PROPN
bjos-8661512	201	3	a	a	PRON
bjos-8661512	201	4	,	,	PUNCT
bjos-8661512	201	5	clavanin	clavanin	PROPN
bjos-8661512	201	6	mo	mo	PROPN
bjos-8661512	201	7	and	and	CCONJ
bjos-8661512	201	8	ll-37	ll-37	PROPN
bjos-8661512	201	9	did	do	AUX
bjos-8661512	201	10	not	not	PART
bjos-8661512	201	11	show	show	VERB
bjos-8661512	201	12	any	any	DET
bjos-8661512	201	13	degree	degree	NOUN
bjos-8661512	201	14	of	of	ADP
bjos-8661512	201	15	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	201	16	to	to	ADP
bjos-8661512	201	17	raw	raw	ADJ
bjos-8661512	201	18	cells	cell	NOUN
bjos-8661512	201	19	.	.	PUNCT
bjos-8661512	202	1	a	a	DET
bjos-8661512	202	2	previous	previous	ADJ
bjos-8661512	202	3	study	study	NOUN
bjos-8661512	202	4	using	use	VERB
bjos-8661512	202	5	clavanin	clavanin	PROPN
bjos-8661512	202	6	a	a	PRON
bjos-8661512	202	7	also	also	ADV
bjos-8661512	202	8	showed	show	VERB
bjos-8661512	202	9	no	no	DET
bjos-8661512	202	10	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	202	11	against	against	ADP
bjos-8661512	202	12	mammalian	mammalian	ADJ
bjos-8661512	202	13	cells	cell	NOUN
bjos-8661512	202	14	(	(	PUNCT
bjos-8661512	202	15	l929	l929	PROPN
bjos-8661512	202	16	)	)	PUNCT
bjos-8661512	202	17	with	with	ADP
bjos-8661512	202	18	low	low	ADJ
bjos-8661512	202	19	concentrations9	concentrations9	NOUN
bjos-8661512	202	20	.	.	PUNCT
bjos-8661512	203	1	moreover	moreover	ADV
bjos-8661512	203	2	,	,	PUNCT
bjos-8661512	203	3	another	another	DET
bjos-8661512	203	4	study	study	NOUN
bjos-8661512	203	5	showed	show	VERB
bjos-8661512	203	6	that	that	SCONJ
bjos-8661512	203	7	128	128	NUM
bjos-8661512	203	8	µg.ml-1	µg.ml-1	NOUN
bjos-8661512	203	9	of	of	ADP
bjos-8661512	203	10	clavanin	clavanin	PROPN
bjos-8661512	203	11	mo	mo	PROPN
bjos-8661512	203	12	did	do	AUX
bjos-8661512	203	13	not	not	PART
bjos-8661512	203	14	demonstrate	demonstrate	VERB
bjos-8661512	203	15	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	203	16	compared	compare	VERB
bjos-8661512	203	17	to	to	ADP
bjos-8661512	203	18	the	the	DET
bjos-8661512	203	19	other	other	ADJ
bjos-8661512	203	20	antimicrobial	antimicrobial	ADJ
bjos-8661512	203	21	agents	agent	NOUN
bjos-8661512	203	22	,	,	PUNCT
bjos-8661512	203	23	with	with	ADP
bjos-8661512	203	24	or	or	CCONJ
bjos-8661512	203	25	without	without	ADP
bjos-8661512	203	26	additional	additional	ADJ
bjos-8661512	203	27	stimulation	stimulation	NOUN
bjos-8661512	203	28	.	.	PUNCT
bjos-8661512	204	1	ll-37	ll-37	NOUN
bjos-8661512	204	2	increased	increase	VERB
bjos-8661512	204	3	cell	cell	NOUN
bjos-8661512	204	4	viability	viability	NOUN
bjos-8661512	204	5	on	on	ADP
bjos-8661512	204	6	raw	raw	ADJ
bjos-8661512	204	7	cells	cell	NOUN
bjos-8661512	204	8	,	,	PUNCT
bjos-8661512	204	9	and	and	CCONJ
bjos-8661512	204	10	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	204	11	did	do	AUX
bjos-8661512	204	12	not	not	PART
bjos-8661512	204	13	interfere	interfere	VERB
bjos-8661512	204	14	with	with	ADP
bjos-8661512	204	15	cell	cell	NOUN
bjos-8661512	204	16	viability	viability	NOUN
bjos-8661512	204	17	at	at	ADP
bjos-8661512	204	18	the	the	DET
bjos-8661512	204	19	same	same	ADJ
bjos-8661512	204	20	concentration	concentration	NOUN
bjos-8661512	204	21	.	.	PUNCT
bjos-8661512	205	1	besides	besides	SCONJ
bjos-8661512	205	2	,	,	PUNCT
bjos-8661512	205	3	after	after	ADP
bjos-8661512	205	4	6	6	NUM
bjos-8661512	205	5	h	h	NOUN
bjos-8661512	205	6	of	of	ADP
bjos-8661512	205	7	incubation	incubation	NOUN
bjos-8661512	205	8	,	,	PUNCT
bjos-8661512	205	9	clavanins	clavanin	NOUN
bjos-8661512	205	10	alone	alone	ADV
bjos-8661512	205	11	reduced	reduce	VERB
bjos-8661512	205	12	cell	cell	NOUN
bjos-8661512	205	13	viability14	viability14	NOUN
bjos-8661512	205	14	.	.	PUNCT
bjos-8661512	206	1	no	no	PRON
bjos-8661512	206	2	regulates	regulate	VERB
bjos-8661512	206	3	bone	bone	NOUN
bjos-8661512	206	4	resorption	resorption	NOUN
bjos-8661512	206	5	through	through	ADP
bjos-8661512	206	6	the	the	DET
bjos-8661512	206	7	regulation	regulation	NOUN
bjos-8661512	206	8	of	of	ADP
bjos-8661512	206	9	the	the	DET
bjos-8661512	206	10	synthesis	synthesis	NOUN
bjos-8661512	206	11	of	of	ADP
bjos-8661512	206	12	opg/	opg/	ADJ
bjos-8661512	206	13	rankl	rankl	NOUN
bjos-8661512	206	14	in	in	ADP
bjos-8661512	206	15	bone	bone	NOUN
bjos-8661512	206	16	marrow	marrow	PROPN
bjos-8661512	206	17	cells21	cells21	PROPN
bjos-8661512	206	18	,	,	PUNCT
bjos-8661512	206	19	although	although	SCONJ
bjos-8661512	206	20	other	other	ADJ
bjos-8661512	206	21	factors	factor	NOUN
bjos-8661512	206	22	,	,	PUNCT
bjos-8661512	206	23	including	include	VERB
bjos-8661512	206	24	cytokines	cytokine	NOUN
bjos-8661512	206	25	,	,	PUNCT
bjos-8661512	206	26	are	be	AUX
bjos-8661512	206	27	also	also	ADV
bjos-8661512	206	28	involved	involve	VERB
bjos-8661512	206	29	.	.	PUNCT
bjos-8661512	207	1	our	our	PRON
bjos-8661512	207	2	results	result	NOUN
bjos-8661512	207	3	demonstrated	demonstrate	VERB
bjos-8661512	207	4	that	that	SCONJ
bjos-8661512	207	5	hdps	hdps	ADJ
bjos-8661512	207	6	downregulated	downregulate	VERB
bjos-8661512	207	7	no	no	DET
bjos-8661512	207	8	production	production	NOUN
bjos-8661512	207	9	with	with	ADP
bjos-8661512	207	10	or	or	CCONJ
bjos-8661512	207	11	without	without	ADP
bjos-8661512	207	12	the	the	DET
bjos-8661512	207	13	stimulation	stimulation	NOUN
bjos-8661512	207	14	of	of	ADP
bjos-8661512	207	15	rrankl	rrankl	NOUN
bjos-8661512	207	16	.	.	PUNCT
bjos-8661512	208	1	accordingly	accordingly	ADV
bjos-8661512	208	2	,	,	PUNCT
bjos-8661512	208	3	clavanin	clavanin	NOUN
bjos-8661512	208	4	a	a	PRON
bjos-8661512	208	5	demonstrated	demonstrate	VERB
bjos-8661512	208	6	a	a	DET
bjos-8661512	208	7	significant	significant	ADJ
bjos-8661512	208	8	reduction	reduction	NOUN
bjos-8661512	208	9	in	in	ADP
bjos-8661512	208	10	the	the	DET
bjos-8661512	208	11	number	number	NOUN
bjos-8661512	208	12	of	of	ADP
bjos-8661512	208	13	osteoclast	osteoclast	ADJ
bjos-8661512	208	14	-	-	PUNCT
bjos-8661512	208	15	like	like	ADJ
bjos-8661512	208	16	cells	cell	NOUN
bjos-8661512	208	17	in	in	ADP
bjos-8661512	208	18	a	a	DET
bjos-8661512	208	19	dose	dose	NOUN
bjos-8661512	208	20	-	-	PUNCT
bjos-8661512	208	21	dependent	dependent	ADJ
bjos-8661512	208	22	manner	manner	NOUN
bjos-8661512	208	23	.	.	PUNCT
bjos-8661512	209	1	clavanin	clavanin	PROPN
bjos-8661512	209	2	mo	mo	PROPN
bjos-8661512	209	3	also	also	ADV
bjos-8661512	209	4	reduced	reduce	VERB
bjos-8661512	209	5	the	the	DET
bjos-8661512	209	6	number	number	NOUN
bjos-8661512	209	7	of	of	ADP
bjos-8661512	209	8	differentiated	differentiated	ADJ
bjos-8661512	209	9	osteoclast	osteoclast	ADJ
bjos-8661512	209	10	-	-	PUNCT
bjos-8661512	209	11	like	like	ADJ
bjos-8661512	209	12	cells	cell	NOUN
bjos-8661512	209	13	.	.	PUNCT
bjos-8661512	210	1	similarly	similarly	ADV
bjos-8661512	210	2	,	,	PUNCT
bjos-8661512	210	3	ll-37	ll-37	NOUN
bjos-8661512	210	4	at	at	ADP
bjos-8661512	210	5	8	8	NUM
bjos-8661512	210	6	and	and	CCONJ
bjos-8661512	210	7	128	128	NUM
bjos-8661512	210	8	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	210	9	demonstrated	demonstrate	VERB
bjos-8661512	210	10	the	the	DET
bjos-8661512	210	11	best	good	ADJ
bjos-8661512	210	12	inhibition	inhibition	NOUN
bjos-8661512	210	13	activity	activity	NOUN
bjos-8661512	210	14	.	.	PUNCT
bjos-8661512	211	1	according	accord	VERB
bjos-8661512	211	2	to	to	ADP
bjos-8661512	211	3	previous	previous	ADJ
bjos-8661512	211	4	results	result	NOUN
bjos-8661512	211	5	,	,	PUNCT
bjos-8661512	211	6	hdps	hdps	NOUN
bjos-8661512	211	7	can	can	AUX
bjos-8661512	211	8	also	also	ADV
bjos-8661512	211	9	modulate	modulate	VERB
bjos-8661512	211	10	inflammatory	inflammatory	ADJ
bjos-8661512	211	11	mediators	mediator	NOUN
bjos-8661512	211	12	that	that	PRON
bjos-8661512	211	13	contribute	contribute	VERB
bjos-8661512	211	14	to	to	ADP
bjos-8661512	211	15	the	the	DET
bjos-8661512	211	16	bone	bone	NOUN
bjos-8661512	211	17	resorption	resorption	NOUN
bjos-8661512	211	18	activation	activation	NOUN
bjos-8661512	211	19	process	process	NOUN
bjos-8661512	211	20	,	,	PUNCT
bjos-8661512	211	21	such	such	ADJ
bjos-8661512	211	22	as	as	ADP
bjos-8661512	211	23	tnf	tnf	PROPN
bjos-8661512	211	24	-	-	PUNCT
bjos-8661512	211	25	α	α	PROPN
bjos-8661512	211	26	,	,	PUNCT
bjos-8661512	211	27	il-6	il-6	NOUN
bjos-8661512	211	28	and	and	CCONJ
bjos-8661512	211	29	il-1α	il-1α	PROPN
bjos-8661512	211	30	,	,	PUNCT
bjos-8661512	211	31	and	and	CCONJ
bjos-8661512	211	32	no	no	DET
bjos-8661512	211	33	production14	production14	NOUN
bjos-8661512	211	34	.	.	PUNCT
bjos-8661512	212	1	different	different	ADJ
bjos-8661512	212	2	substances	substance	NOUN
bjos-8661512	212	3	already	already	ADV
bjos-8661512	212	4	used	use	VERB
bjos-8661512	212	5	in	in	ADP
bjos-8661512	212	6	clinical	clinical	ADJ
bjos-8661512	212	7	practice	practice	NOUN
bjos-8661512	212	8	were	be	AUX
bjos-8661512	212	9	also	also	ADV
bjos-8661512	212	10	evaluated	evaluate	VERB
bjos-8661512	212	11	in	in	ADP
bjos-8661512	212	12	this	this	DET
bjos-8661512	212	13	study	study	NOUN
bjos-8661512	212	14	.	.	PUNCT
bjos-8661512	213	1	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	213	2	did	do	AUX
bjos-8661512	213	3	not	not	PART
bjos-8661512	213	4	show	show	VERB
bjos-8661512	213	5	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	213	6	,	,	PUNCT
bjos-8661512	213	7	and	and	CCONJ
bjos-8661512	213	8	doxycycline	doxycycline	NOUN
bjos-8661512	213	9	demonstrated	demonstrate	VERB
bjos-8661512	213	10	a	a	DET
bjos-8661512	213	11	toxic	toxic	ADJ
bjos-8661512	213	12	effect	effect	NOUN
bjos-8661512	213	13	on	on	ADP
bjos-8661512	213	14	cells	cell	NOUN
bjos-8661512	213	15	at	at	ADP
bjos-8661512	213	16	high	high	ADJ
bjos-8661512	213	17	concentration	concentration	NOUN
bjos-8661512	213	18	and	and	CCONJ
bjos-8661512	213	19	increased	increase	VERB
bjos-8661512	213	20	cell	cell	NOUN
bjos-8661512	213	21	viability	viability	NOUN
bjos-8661512	213	22	at	at	ADP
bjos-8661512	213	23	low	low	ADJ
bjos-8661512	213	24	concentration	concentration	NOUN
bjos-8661512	213	25	.	.	PUNCT
bjos-8661512	214	1	accordingly	accordingly	ADV
bjos-8661512	214	2	,	,	PUNCT
bjos-8661512	214	3	a	a	DET
bjos-8661512	214	4	study	study	NOUN
bjos-8661512	214	5	evaluated	evaluate	VERB
bjos-8661512	214	6	the	the	DET
bjos-8661512	214	7	effects	effect	NOUN
bjos-8661512	214	8	of	of	ADP
bjos-8661512	214	9	a	a	DET
bjos-8661512	214	10	sub	sub	ADJ
bjos-8661512	214	11	-	-	ADJ
bjos-8661512	214	12	antimicrobial	antimicrobial	ADJ
bjos-8661512	214	13	dose	dose	NOUN
bjos-8661512	214	14	of	of	ADP
bjos-8661512	214	15	doxycycline	doxycycline	NOUN
bjos-8661512	214	16	(	(	PUNCT
bjos-8661512	214	17	sdd	sdd	NOUN
bjos-8661512	214	18	)	)	PUNCT
bjos-8661512	214	19	on	on	ADP
bjos-8661512	214	20	ligature	ligature	NOUN
bjos-8661512	214	21	-	-	PUNCT
bjos-8661512	214	22	induced	induce	VERB
bjos-8661512	214	23	periodontitis	periodontitis	NOUN
bjos-8661512	214	24	in	in	ADP
bjos-8661512	214	25	spontaneously	spontaneously	ADV
bjos-8661512	214	26	hypertensive	hypertensive	ADJ
bjos-8661512	214	27	rats	rat	NOUN
bjos-8661512	214	28	.	.	PUNCT
bjos-8661512	215	1	it	it	PRON
bjos-8661512	215	2	concluded	conclude	VERB
bjos-8661512	215	3	that	that	SCONJ
bjos-8661512	215	4	sdd	sdd	NOUN
bjos-8661512	215	5	therapy	therapy	NOUN
bjos-8661512	215	6	exerted	exert	VERB
bjos-8661512	215	7	a	a	DET
bjos-8661512	215	8	systemic	systemic	ADJ
bjos-8661512	215	9	modulating	modulating	ADJ
bjos-8661512	215	10	effect	effect	NOUN
bjos-8661512	215	11	on	on	ADP
bjos-8661512	215	12	inflammation	inflammation	NOUN
bjos-8661512	215	13	,	,	PUNCT
bjos-8661512	215	14	with	with	ADP
bjos-8661512	215	15	reduced	reduced	ADJ
bjos-8661512	215	16	periodontal	periodontal	ADJ
bjos-8661512	215	17	tissue	tissue	NOUN
bjos-8661512	215	18	destruction	destruction	NOUN
bjos-8661512	215	19	in	in	ADP
bjos-8661512	215	20	hypertensive	hypertensive	ADJ
bjos-8661512	215	21	rats22	rats22	NOUN
bjos-8661512	215	22	.	.	PUNCT
bjos-8661512	216	1	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	216	2	presented	present	VERB
bjos-8661512	216	3	similar	similar	ADJ
bjos-8661512	216	4	no	no	DET
bjos-8661512	216	5	results	result	NOUN
bjos-8661512	216	6	compared	compare	VERB
bjos-8661512	216	7	to	to	ADP
bjos-8661512	216	8	hdps	hdps	ADV
bjos-8661512	216	9	,	,	PUNCT
bjos-8661512	216	10	and	and	CCONJ
bjos-8661512	216	11	doxycycline	doxycycline	NOUN
bjos-8661512	216	12	presented	present	VERB
bjos-8661512	216	13	an	an	DET
bjos-8661512	216	14	increase	increase	NOUN
bjos-8661512	216	15	in	in	ADP
bjos-8661512	216	16	no	no	DET
bjos-8661512	216	17	levels	level	NOUN
bjos-8661512	216	18	,	,	PUNCT
bjos-8661512	216	19	especially	especially	ADV
bjos-8661512	216	20	at	at	ADP
bjos-8661512	216	21	2	2	NUM
bjos-8661512	216	22	µg.ml-1	µg.ml-1	ADJ
bjos-8661512	216	23	.	.	PUNCT
bjos-8661512	217	1	in	in	ADP
bjos-8661512	217	2	the	the	DET
bjos-8661512	217	3	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	217	4	process	process	NOUN
bjos-8661512	217	5	,	,	PUNCT
bjos-8661512	217	6	both	both	DET
bjos-8661512	217	7	tested	test	VERB
bjos-8661512	217	8	drugs	drug	NOUN
bjos-8661512	217	9	decreased	decrease	VERB
bjos-8661512	217	10	the	the	DET
bjos-8661512	217	11	number	number	NOUN
bjos-8661512	217	12	of	of	ADP
bjos-8661512	217	13	osteoclast	osteoclast	ADJ
bjos-8661512	217	14	-	-	PUNCT
bjos-8661512	217	15	like	like	ADJ
bjos-8661512	217	16	cells	cell	NOUN
bjos-8661512	217	17	in	in	ADP
bjos-8661512	217	18	the	the	DET
bjos-8661512	217	19	presence	presence	NOUN
bjos-8661512	217	20	of	of	ADP
bjos-8661512	217	21	all	all	DET
bjos-8661512	217	22	concentrations	concentration	NOUN
bjos-8661512	217	23	tested	test	VERB
bjos-8661512	217	24	.	.	PUNCT
bjos-8661512	218	1	these	these	DET
bjos-8661512	218	2	facts	fact	NOUN
bjos-8661512	218	3	suggest	suggest	VERB
bjos-8661512	218	4	that	that	SCONJ
bjos-8661512	218	5	although	although	SCONJ
bjos-8661512	218	6	no	no	PRON
bjos-8661512	218	7	is	be	AUX
bjos-8661512	218	8	strongly	strongly	ADV
bjos-8661512	218	9	associated	associate	VERB
bjos-8661512	218	10	with	with	ADP
bjos-8661512	218	11	osteoclast	osteoclast	ADJ
bjos-8661512	218	12	differentiation	differentiation	NOUN
bjos-8661512	218	13	,	,	PUNCT
bjos-8661512	218	14	this	this	PRON
bjos-8661512	218	15	is	be	AUX
bjos-8661512	218	16	not	not	PART
bjos-8661512	218	17	the	the	DET
bjos-8661512	218	18	only	only	ADJ
bjos-8661512	218	19	factor	factor	NOUN
bjos-8661512	218	20	involved	involve	VERB
bjos-8661512	218	21	in	in	ADP
bjos-8661512	218	22	the	the	DET
bjos-8661512	218	23	osteoclasto10	osteoclasto10	ADJ
bjos-8661512	218	24	amorim	amorim	PROPN
bjos-8661512	218	25	et	et	PROPN
bjos-8661512	218	26	al	al	PROPN
bjos-8661512	218	27	.	.	PUNCT
bjos-8661512	218	28	genesis	genesis	PROPN
bjos-8661512	218	29	process23	process23	PROPN
bjos-8661512	218	30	.	.	PUNCT
bjos-8661512	219	1	also	also	ADV
bjos-8661512	219	2	,	,	PUNCT
bjos-8661512	219	3	doxycycline	doxycycline	NOUN
bjos-8661512	219	4	might	might	AUX
bjos-8661512	219	5	have	have	VERB
bjos-8661512	219	6	another	another	DET
bjos-8661512	219	7	mechanism	mechanism	NOUN
bjos-8661512	219	8	for	for	ADP
bjos-8661512	219	9	downregulating	downregulate	VERB
bjos-8661512	219	10	the	the	DET
bjos-8661512	219	11	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	219	12	pathway23	pathway23	NOUN
bjos-8661512	219	13	.	.	PUNCT
bjos-8661512	220	1	however	however	ADV
bjos-8661512	220	2	,	,	PUNCT
bjos-8661512	220	3	these	these	DET
bjos-8661512	220	4	results	result	NOUN
bjos-8661512	220	5	are	be	AUX
bjos-8661512	220	6	in	in	ADP
bjos-8661512	220	7	agreement	agreement	NOUN
bjos-8661512	220	8	with	with	ADP
bjos-8661512	220	9	previous	previous	ADJ
bjos-8661512	220	10	results	result	NOUN
bjos-8661512	220	11	that	that	PRON
bjos-8661512	220	12	suggest	suggest	VERB
bjos-8661512	220	13	the	the	DET
bjos-8661512	220	14	inhibition	inhibition	NOUN
bjos-8661512	220	15	of	of	ADP
bjos-8661512	220	16	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	220	17	in	in	ADP
bjos-8661512	220	18	raw	raw	ADJ
bjos-8661512	220	19	cells	cell	NOUN
bjos-8661512	220	20	in	in	ADP
bjos-8661512	220	21	the	the	DET
bjos-8661512	220	22	presence	presence	NOUN
bjos-8661512	220	23	of	of	ADP
bjos-8661512	220	24	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	220	25	23	23	NUM
bjos-8661512	220	26	.	.	PUNCT
bjos-8661512	221	1	other	other	ADJ
bjos-8661512	221	2	studies	study	NOUN
bjos-8661512	221	3	suggest	suggest	VERB
bjos-8661512	221	4	that	that	SCONJ
bjos-8661512	221	5	the	the	DET
bjos-8661512	221	6	alkaline	alkaline	NOUN
bjos-8661512	221	7	ph	ph	NOUN
bjos-8661512	221	8	of	of	ADP
bjos-8661512	221	9	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	221	10	can	can	AUX
bjos-8661512	221	11	neutralize	neutralize	VERB
bjos-8661512	221	12	the	the	DET
bjos-8661512	221	13	lactic	lactic	ADJ
bjos-8661512	221	14	acid	acid	NOUN
bjos-8661512	221	15	secreted	secrete	VERB
bjos-8661512	221	16	by	by	ADP
bjos-8661512	221	17	osteoclasts	osteoclast	NOUN
bjos-8661512	221	18	and	and	CCONJ
bjos-8661512	221	19	may	may	AUX
bjos-8661512	221	20	help	help	VERB
bjos-8661512	221	21	prevent	prevent	VERB
bjos-8661512	221	22	the	the	DET
bjos-8661512	221	23	destruction	destruction	NOUN
bjos-8661512	221	24	of	of	ADP
bjos-8661512	221	25	mineralized	mineralize	VERB
bjos-8661512	221	26	tissue24	tissue24	NOUN
bjos-8661512	221	27	.	.	PUNCT
bjos-8661512	222	1	in	in	ADP
bjos-8661512	222	2	summary	summary	NOUN
bjos-8661512	222	3	,	,	PUNCT
bjos-8661512	222	4	this	this	DET
bjos-8661512	222	5	study	study	NOUN
bjos-8661512	222	6	aims	aim	VERB
bjos-8661512	222	7	to	to	PART
bjos-8661512	222	8	initiate	initiate	VERB
bjos-8661512	222	9	the	the	DET
bjos-8661512	222	10	assessment	assessment	NOUN
bjos-8661512	222	11	of	of	ADP
bjos-8661512	222	12	the	the	DET
bjos-8661512	222	13	biotechnological	biotechnological	ADJ
bjos-8661512	222	14	potential	potential	NOUN
bjos-8661512	222	15	of	of	ADP
bjos-8661512	222	16	hdps	hdps	PROPN
bjos-8661512	222	17	clavanin	clavanin	PROPN
bjos-8661512	222	18	a	a	PRON
bjos-8661512	222	19	and	and	CCONJ
bjos-8661512	222	20	mo	mo	NOUN
bjos-8661512	222	21	in	in	ADP
bjos-8661512	222	22	the	the	DET
bjos-8661512	222	23	oral	oral	ADJ
bjos-8661512	222	24	osteoimmunological	osteoimmunological	ADJ
bjos-8661512	222	25	context	context	NOUN
bjos-8661512	222	26	and	and	CCONJ
bjos-8661512	222	27	their	their	PRON
bjos-8661512	222	28	capability	capability	NOUN
bjos-8661512	222	29	to	to	PART
bjos-8661512	222	30	reduce	reduce	VERB
bjos-8661512	222	31	in	in	ADP
bjos-8661512	222	32	vitro	vitro	X
bjos-8661512	222	33	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	222	34	,	,	PUNCT
bjos-8661512	222	35	compared	compare	VERB
bjos-8661512	222	36	to	to	ADP
bjos-8661512	222	37	ll-37	ll-37	NOUN
bjos-8661512	222	38	(	(	PUNCT
bjos-8661512	222	39	hdp	hdp	PROPN
bjos-8661512	222	40	control	control	PROPN
bjos-8661512	222	41	)	)	PUNCT
bjos-8661512	222	42	,	,	PUNCT
bjos-8661512	222	43	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	222	44	(	(	PUNCT
bjos-8661512	222	45	used	use	VERB
bjos-8661512	222	46	in	in	ADP
bjos-8661512	222	47	the	the	DET
bjos-8661512	222	48	endodontic	endodontic	ADJ
bjos-8661512	222	49	treatment	treatment	NOUN
bjos-8661512	222	50	)	)	PUNCT
bjos-8661512	222	51	and	and	CCONJ
bjos-8661512	222	52	doxycycline	doxycycline	NOUN
bjos-8661512	222	53	(	(	PUNCT
bjos-8661512	222	54	used	use	VERB
bjos-8661512	222	55	in	in	ADP
bjos-8661512	222	56	the	the	DET
bjos-8661512	222	57	periodontal	periodontal	ADJ
bjos-8661512	222	58	treatment	treatment	NOUN
bjos-8661512	222	59	)	)	PUNCT
bjos-8661512	222	60	.	.	PUNCT
bjos-8661512	223	1	we	we	PRON
bjos-8661512	223	2	highlighted	highlight	VERB
bjos-8661512	223	3	the	the	DET
bjos-8661512	223	4	results	result	NOUN
bjos-8661512	223	5	observed	observe	VERB
bjos-8661512	223	6	in	in	ADP
bjos-8661512	223	7	the	the	DET
bjos-8661512	223	8	presence	presence	NOUN
bjos-8661512	223	9	of	of	ADP
bjos-8661512	223	10	8	8	NUM
bjos-8661512	223	11	μg.ml-1	μg.ml-1	NOUN
bjos-8661512	223	12	of	of	ADP
bjos-8661512	223	13	ll-37	ll-37	NOUN
bjos-8661512	223	14	and	and	CCONJ
bjos-8661512	223	15	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	223	16	,	,	PUNCT
bjos-8661512	223	17	thus	thus	ADV
bjos-8661512	223	18	considering	consider	VERB
bjos-8661512	223	19	the	the	DET
bjos-8661512	223	20	use	use	NOUN
bjos-8661512	223	21	of	of	ADP
bjos-8661512	223	22	these	these	DET
bjos-8661512	223	23	peptides	peptide	NOUN
bjos-8661512	223	24	as	as	ADP
bjos-8661512	223	25	a	a	DET
bjos-8661512	223	26	possible	possible	ADJ
bjos-8661512	223	27	product	product	NOUN
bjos-8661512	223	28	for	for	ADP
bjos-8661512	223	29	endodontic	endodontic	ADJ
bjos-8661512	223	30	and	and	CCONJ
bjos-8661512	223	31	periodontal	periodontal	ADJ
bjos-8661512	223	32	applications	application	NOUN
bjos-8661512	223	33	,	,	PUNCT
bjos-8661512	223	34	in	in	ADP
bjos-8661512	223	35	order	order	NOUN
bjos-8661512	223	36	to	to	PART
bjos-8661512	223	37	reduce	reduce	VERB
bjos-8661512	223	38	the	the	DET
bjos-8661512	223	39	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	223	40	process	process	NOUN
bjos-8661512	223	41	.	.	PUNCT
bjos-8661512	224	1	on	on	ADP
bjos-8661512	224	2	the	the	DET
bjos-8661512	224	3	other	other	ADJ
bjos-8661512	224	4	hand	hand	NOUN
bjos-8661512	224	5	,	,	PUNCT
bjos-8661512	224	6	ca(oh)2	ca(oh)2	NOUN
bjos-8661512	224	7	shows	show	VERB
bjos-8661512	224	8	low	low	ADJ
bjos-8661512	224	9	production	production	NOUN
bjos-8661512	224	10	costs	cost	NOUN
bjos-8661512	224	11	when	when	SCONJ
bjos-8661512	224	12	compared	compare	VERB
bjos-8661512	224	13	to	to	ADP
bjos-8661512	224	14	ll-37	ll-37	NOUN
bjos-8661512	224	15	.	.	PUNCT
bjos-8661512	225	1	this	this	DET
bjos-8661512	225	2	hdp	hdp	NOUN
bjos-8661512	225	3	presents	present	VERB
bjos-8661512	225	4	a	a	DET
bjos-8661512	225	5	relatively	relatively	ADV
bjos-8661512	225	6	long	long	ADJ
bjos-8661512	225	7	sequence	sequence	NOUN
bjos-8661512	225	8	of	of	ADP
bjos-8661512	225	9	amino	amino	ADJ
bjos-8661512	225	10	acids	acid	NOUN
bjos-8661512	225	11	,	,	PUNCT
bjos-8661512	225	12	which	which	PRON
bjos-8661512	225	13	raises	raise	VERB
bjos-8661512	225	14	its	its	PRON
bjos-8661512	225	15	cost	cost	NOUN
bjos-8661512	225	16	for	for	ADP
bjos-8661512	225	17	synthesis	synthesis	NOUN
bjos-8661512	225	18	,	,	PUNCT
bjos-8661512	225	19	and	and	CCONJ
bjos-8661512	225	20	it	it	PRON
bjos-8661512	225	21	would	would	AUX
bjos-8661512	225	22	probably	probably	ADV
bjos-8661512	225	23	only	only	ADV
bjos-8661512	225	24	be	be	AUX
bjos-8661512	225	25	indicated	indicate	VERB
bjos-8661512	225	26	for	for	ADP
bjos-8661512	225	27	restricted	restricted	ADJ
bjos-8661512	225	28	cases	case	NOUN
bjos-8661512	225	29	.	.	PUNCT
bjos-8661512	226	1	indeed	indeed	ADV
bjos-8661512	226	2	,	,	PUNCT
bjos-8661512	226	3	because	because	SCONJ
bjos-8661512	226	4	of	of	ADP
bjos-8661512	226	5	its	its	PRON
bjos-8661512	226	6	immunomodulatory	immunomodulatory	ADJ
bjos-8661512	226	7	benefits	benefit	NOUN
bjos-8661512	226	8	and	and	CCONJ
bjos-8661512	226	9	its	its	PRON
bjos-8661512	226	10	biocompatibility	biocompatibility	NOUN
bjos-8661512	226	11	,	,	PUNCT
bjos-8661512	226	12	by	by	ADP
bjos-8661512	226	13	being	be	AUX
bjos-8661512	226	14	a	a	DET
bjos-8661512	226	15	peptide	peptide	ADJ
bjos-8661512	226	16	present	present	NOUN
bjos-8661512	226	17	in	in	ADP
bjos-8661512	226	18	the	the	DET
bjos-8661512	226	19	oral	oral	ADJ
bjos-8661512	226	20	cavity	cavity	NOUN
bjos-8661512	226	21	,	,	PUNCT
bjos-8661512	226	22	ll-37	ll-37	NOUN
bjos-8661512	226	23	presents	present	VERB
bjos-8661512	226	24	itself	itself	PRON
bjos-8661512	226	25	as	as	ADP
bjos-8661512	226	26	a	a	DET
bjos-8661512	226	27	good	good	ADJ
bjos-8661512	226	28	candidate	candidate	NOUN
bjos-8661512	226	29	for	for	ADP
bjos-8661512	226	30	dentistry	dentistry	NOUN
bjos-8661512	226	31	use	use	NOUN
bjos-8661512	226	32	.	.	PUNCT
bjos-8661512	227	1	when	when	SCONJ
bjos-8661512	227	2	ll-37	ll-37	NOUN
bjos-8661512	227	3	results	result	NOUN
bjos-8661512	227	4	were	be	AUX
bjos-8661512	227	5	compared	compare	VERB
bjos-8661512	227	6	to	to	ADP
bjos-8661512	227	7	the	the	DET
bjos-8661512	227	8	doxycycline	doxycycline	NOUN
bjos-8661512	227	9	,	,	PUNCT
bjos-8661512	227	10	the	the	DET
bjos-8661512	227	11	hdp	hdp	NOUN
bjos-8661512	227	12	demonstrated	demonstrate	VERB
bjos-8661512	227	13	better	well	ADJ
bjos-8661512	227	14	efficiency	efficiency	NOUN
bjos-8661512	227	15	in	in	ADP
bjos-8661512	227	16	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	227	17	downregulation	downregulation	NOUN
bjos-8661512	227	18	at	at	ADP
bjos-8661512	227	19	low	low	ADJ
bjos-8661512	227	20	concentrations	concentration	NOUN
bjos-8661512	227	21	,	,	PUNCT
bjos-8661512	227	22	thus	thus	ADV
bjos-8661512	227	23	showing	show	VERB
bjos-8661512	227	24	an	an	DET
bjos-8661512	227	25	even	even	ADV
bjos-8661512	227	26	greater	great	ADJ
bjos-8661512	227	27	potential	potential	NOUN
bjos-8661512	227	28	in	in	ADP
bjos-8661512	227	29	the	the	DET
bjos-8661512	227	30	context	context	NOUN
bjos-8661512	227	31	of	of	ADP
bjos-8661512	227	32	periodontal	periodontal	ADJ
bjos-8661512	227	33	bone	bone	NOUN
bjos-8661512	227	34	loss	loss	NOUN
bjos-8661512	227	35	.	.	PUNCT
bjos-8661512	228	1	despite	despite	SCONJ
bjos-8661512	228	2	the	the	DET
bjos-8661512	228	3	benefits	benefit	NOUN
bjos-8661512	228	4	highlighted	highlight	VERB
bjos-8661512	228	5	in	in	ADP
bjos-8661512	228	6	these	these	DET
bjos-8661512	228	7	data	datum	NOUN
bjos-8661512	228	8	,	,	PUNCT
bjos-8661512	228	9	in	in	ADP
bjos-8661512	228	10	vitro	vitro	X
bjos-8661512	228	11	results	result	NOUN
bjos-8661512	228	12	should	should	AUX
bjos-8661512	228	13	be	be	AUX
bjos-8661512	228	14	interpreted	interpret	VERB
bjos-8661512	228	15	with	with	ADP
bjos-8661512	228	16	caution	caution	NOUN
bjos-8661512	228	17	and	and	CCONJ
bjos-8661512	228	18	other	other	ADJ
bjos-8661512	228	19	in	in	ADP
bjos-8661512	228	20	vivo	vivo	ADJ
bjos-8661512	228	21	studies	study	NOUN
bjos-8661512	228	22	are	be	AUX
bjos-8661512	228	23	necessary	necessary	ADJ
bjos-8661512	228	24	to	to	PART
bjos-8661512	228	25	evaluate	evaluate	VERB
bjos-8661512	228	26	the	the	DET
bjos-8661512	228	27	potential	potential	NOUN
bjos-8661512	228	28	of	of	ADP
bjos-8661512	228	29	this	this	DET
bjos-8661512	228	30	biomolecule	biomolecule	NOUN
bjos-8661512	228	31	for	for	ADP
bjos-8661512	228	32	clinical	clinical	ADJ
bjos-8661512	228	33	use	use	NOUN
bjos-8661512	228	34	.	.	PUNCT
bjos-8661512	229	1	other	other	ADJ
bjos-8661512	229	2	important	important	ADJ
bjos-8661512	229	3	points	point	NOUN
bjos-8661512	229	4	for	for	ADP
bjos-8661512	229	5	future	future	ADJ
bjos-8661512	229	6	investigations	investigation	NOUN
bjos-8661512	229	7	should	should	AUX
bjos-8661512	229	8	be	be	AUX
bjos-8661512	229	9	focused	focus	VERB
bjos-8661512	229	10	on	on	ADP
bjos-8661512	229	11	the	the	DET
bjos-8661512	229	12	large	large	ADJ
bjos-8661512	229	13	-	-	PUNCT
bjos-8661512	229	14	scale	scale	NOUN
bjos-8661512	229	15	expression	expression	NOUN
bjos-8661512	229	16	of	of	ADP
bjos-8661512	229	17	this	this	DET
bjos-8661512	229	18	peptide	peptide	NOUN
bjos-8661512	229	19	(	(	PUNCT
bjos-8661512	229	20	lowering	lower	VERB
bjos-8661512	229	21	its	its	PRON
bjos-8661512	229	22	cost	cost	NOUN
bjos-8661512	229	23	)	)	PUNCT
bjos-8661512	229	24	,	,	PUNCT
bjos-8661512	229	25	and	and	CCONJ
bjos-8661512	229	26	the	the	DET
bjos-8661512	229	27	analysis	analysis	NOUN
bjos-8661512	229	28	of	of	ADP
bjos-8661512	229	29	its	its	PRON
bjos-8661512	229	30	integrity	integrity	NOUN
bjos-8661512	229	31	through	through	ADP
bjos-8661512	229	32	various	various	ADJ
bjos-8661512	229	33	oral	oral	ADJ
bjos-8661512	229	34	conditions	condition	NOUN
bjos-8661512	229	35	,	,	PUNCT
bjos-8661512	229	36	such	such	ADJ
bjos-8661512	229	37	as	as	ADP
bjos-8661512	229	38	temperature	temperature	NOUN
bjos-8661512	229	39	changes	change	NOUN
bjos-8661512	229	40	,	,	PUNCT
bjos-8661512	229	41	ph	ph	NOUN
bjos-8661512	229	42	,	,	PUNCT
bjos-8661512	229	43	and	and	CCONJ
bjos-8661512	229	44	presence	presence	NOUN
bjos-8661512	229	45	of	of	ADP
bjos-8661512	229	46	lytic	lytic	ADJ
bjos-8661512	229	47	enzymes	enzyme	NOUN
bjos-8661512	229	48	.	.	PUNCT
bjos-8661512	230	1	in	in	ADP
bjos-8661512	230	2	addition	addition	NOUN
bjos-8661512	230	3	,	,	PUNCT
bjos-8661512	230	4	other	other	ADJ
bjos-8661512	230	5	parameters	parameter	NOUN
bjos-8661512	230	6	should	should	AUX
bjos-8661512	230	7	be	be	AUX
bjos-8661512	230	8	evaluated	evaluate	VERB
bjos-8661512	230	9	,	,	PUNCT
bjos-8661512	230	10	such	such	ADJ
bjos-8661512	230	11	as	as	ADP
bjos-8661512	230	12	the	the	DET
bjos-8661512	230	13	peptides	peptide	NOUN
bjos-8661512	230	14	’	'	PUNCT
bjos-8661512	230	15	mechanism	mechanism	NOUN
bjos-8661512	230	16	of	of	ADP
bjos-8661512	230	17	action	action	NOUN
bjos-8661512	230	18	in	in	ADP
bjos-8661512	230	19	the	the	DET
bjos-8661512	230	20	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	230	21	process	process	NOUN
bjos-8661512	230	22	,	,	PUNCT
bjos-8661512	230	23	in	in	ADP
bjos-8661512	230	24	order	order	NOUN
bjos-8661512	230	25	to	to	PART
bjos-8661512	230	26	enhance	enhance	VERB
bjos-8661512	230	27	the	the	DET
bjos-8661512	230	28	knowledge	knowledge	NOUN
bjos-8661512	230	29	on	on	ADP
bjos-8661512	230	30	these	these	DET
bjos-8661512	230	31	potential	potential	ADJ
bjos-8661512	230	32	products	product	NOUN
bjos-8661512	230	33	indicated	indicate	VERB
bjos-8661512	230	34	for	for	ADP
bjos-8661512	230	35	bone	bone	NOUN
bjos-8661512	230	36	resorption	resorption	NOUN
bjos-8661512	230	37	processes	process	NOUN
bjos-8661512	230	38	,	,	PUNCT
bjos-8661512	230	39	present	present	ADJ
bjos-8661512	230	40	in	in	ADP
bjos-8661512	230	41	the	the	DET
bjos-8661512	230	42	periradicular	periradicular	ADJ
bjos-8661512	230	43	area	area	NOUN
bjos-8661512	230	44	and	and	CCONJ
bjos-8661512	230	45	periodontitis	periodontitis	NOUN
bjos-8661512	230	46	.	.	PUNCT
bjos-8661512	231	1	acknowledgments	acknowledgment	NOUN
bjos-8661512	231	2	this	this	DET
bjos-8661512	231	3	work	work	NOUN
bjos-8661512	231	4	was	be	AUX
bjos-8661512	231	5	supported	support	VERB
bjos-8661512	231	6	by	by	ADP
bjos-8661512	231	7	the	the	DET
bjos-8661512	231	8	conselho	conselho	PROPN
bjos-8661512	231	9	nacional	nacional	PROPN
bjos-8661512	231	10	de	de	X
bjos-8661512	231	11	desenvolvimento	desenvolvimento	PROPN
bjos-8661512	231	12	científico	científico	PROPN
bjos-8661512	231	13	e	e	NOUN
bjos-8661512	231	14	tecnológico	tecnológico	PROPN
bjos-8661512	231	15	(	(	PUNCT
bjos-8661512	231	16	cnpq	cnpq	NOUN
bjos-8661512	231	17	)	)	PUNCT
bjos-8661512	231	18	grant	grant	NOUN
bjos-8661512	231	19	:	:	PUNCT
bjos-8661512	231	20	409196/2018	409196/2018	NUM
bjos-8661512	231	21	-	-	SYM
bjos-8661512	231	22	5	5	NUM
bjos-8661512	231	23	,	,	PUNCT
bjos-8661512	231	24	coordenação	coordenação	PROPN
bjos-8661512	231	25	de	de	PROPN
bjos-8661512	231	26	aperfeiçoamento	aperfeiçoamento	PROPN
bjos-8661512	231	27	de	de	X
bjos-8661512	231	28	pessoal	pessoal	PROPN
bjos-8661512	231	29	de	de	PROPN
bjos-8661512	231	30	nível	nível	PROPN
bjos-8661512	231	31	superior	superior	ADJ
bjos-8661512	231	32	(	(	PUNCT
bjos-8661512	231	33	capes	cape	NOUN
bjos-8661512	231	34	)	)	PUNCT
bjos-8661512	231	35	,	,	PUNCT
bjos-8661512	231	36	fundação	fundação	NOUN
bjos-8661512	231	37	de	de	X
bjos-8661512	231	38	apoio	apoio	X
bjos-8661512	231	39	à	à	X
bjos-8661512	231	40	pesquisa	pesquisa	PROPN
bjos-8661512	231	41	do	do	AUX
bjos-8661512	231	42	distrito	distrito	PROPN
bjos-8661512	231	43	federal	federal	PROPN
bjos-8661512	231	44	(	(	PUNCT
bjos-8661512	231	45	fapdf	fapdf	PROPN
bjos-8661512	231	46	)	)	PUNCT
bjos-8661512	231	47	grant	grant	NOUN
bjos-8661512	231	48	:	:	PUNCT
bjos-8661512	231	49	0193.001702/2017	0193.001702/2017	NUM
bjos-8661512	231	50	and	and	CCONJ
bjos-8661512	231	51	fundação	fundação	PROPN
bjos-8661512	231	52	de	de	PROPN
bjos-8661512	231	53	apoio	apoio	PROPN
bjos-8661512	231	54	ao	ao	PROPN
bjos-8661512	231	55	desenvolvimento	desenvolvimento	PROPN
bjos-8661512	231	56	do	do	PROPN
bjos-8661512	231	57	ensino	ensino	PROPN
bjos-8661512	231	58	,	,	PUNCT
bjos-8661512	231	59	ciência	ciência	PROPN
bjos-8661512	231	60	e	e	NOUN
bjos-8661512	231	61	tecnologia	tecnologia	NOUN
bjos-8661512	231	62	do	do	AUX
bjos-8661512	231	63	estado	estado	PROPN
bjos-8661512	231	64	de	de	PROPN
bjos-8661512	231	65	mato	mato	PROPN
bjos-8661512	231	66	grosso	grosso	PROPN
bjos-8661512	231	67	do	do	VERB
bjos-8661512	231	68	sul	sul	PROPN
bjos-8661512	231	69	(	(	PUNCT
bjos-8661512	231	70	fundect	fundect	PROPN
bjos-8661512	231	71	)	)	PUNCT
bjos-8661512	231	72	.	.	PUNCT
bjos-8661512	232	1	the	the	DET
bjos-8661512	232	2	authors	author	NOUN
bjos-8661512	232	3	deny	deny	VERB
bjos-8661512	232	4	any	any	DET
bjos-8661512	232	5	conflicts	conflict	NOUN
bjos-8661512	232	6	of	of	ADP
bjos-8661512	232	7	interest	interest	NOUN
bjos-8661512	232	8	related	relate	VERB
bjos-8661512	232	9	to	to	ADP
bjos-8661512	232	10	this	this	DET
bjos-8661512	232	11	study	study	NOUN
bjos-8661512	232	12	.	.	PUNCT
bjos-8661512	233	1	references	reference	NOUN
bjos-8661512	233	2	1	1	NUM
bjos-8661512	233	3	.	.	PUNCT
bjos-8661512	233	4	schett	schett	PROPN
bjos-8661512	233	5	g	g	PROPN
bjos-8661512	233	6	,	,	PUNCT
bjos-8661512	233	7	gravallese	gravallese	PROPN
bjos-8661512	233	8	e.	e.	PROPN
bjos-8661512	233	9	bone	bone	PROPN
bjos-8661512	233	10	erosion	erosion	NOUN
bjos-8661512	233	11	in	in	ADP
bjos-8661512	233	12	rheumatoid	rheumatoid	NOUN
bjos-8661512	233	13	arthritis	arthritis	NOUN
bjos-8661512	233	14	:	:	PUNCT
bjos-8661512	233	15	mechanisms	mechanism	NOUN
bjos-8661512	233	16	,	,	PUNCT
bjos-8661512	233	17	diagnosis	diagnosis	NOUN
bjos-8661512	233	18	and	and	CCONJ
bjos-8661512	233	19	treatment	treatment	NOUN
bjos-8661512	233	20	.	.	PUNCT
bjos-8661512	234	1	nat	nat	PROPN
bjos-8661512	234	2	rev	rev	PROPN
bjos-8661512	234	3	rheumatol	rheumatol	NOUN
bjos-8661512	234	4	.	.	PUNCT
bjos-8661512	235	1	2012;8(11):656	2012;8(11):656	NUM
bjos-8661512	235	2	-	-	SYM
bjos-8661512	235	3	64	64	NUM
bjos-8661512	235	4	.	.	PUNCT
bjos-8661512	236	1	doi:10.1038	doi:10.1038	NOUN
bjos-8661512	236	2	/	/	SYM
bjos-8661512	236	3	nrrheum.2012.153	nrrheum.2012.153	PROPN
bjos-8661512	236	4	.	.	PROPN
bjos-8661512	236	5	11	11	NUM
bjos-8661512	236	6	amorim	amorim	NOUN
bjos-8661512	236	7	et	et	PROPN
bjos-8661512	236	8	al	al	PROPN
bjos-8661512	236	9	.	.	PROPN
bjos-8661512	236	10	2	2	NUM
bjos-8661512	236	11	.	.	X
bjos-8661512	236	12	park	park	NOUN
bjos-8661512	236	13	-	-	PUNCT
bjos-8661512	236	14	min	min	PROPN
bjos-8661512	236	15	kh	kh	PROPN
bjos-8661512	236	16	.	.	PROPN
bjos-8661512	236	17	mechanisms	mechanism	NOUN
bjos-8661512	236	18	involved	involve	VERB
bjos-8661512	236	19	in	in	ADP
bjos-8661512	236	20	normal	normal	ADJ
bjos-8661512	236	21	and	and	CCONJ
bjos-8661512	236	22	pathological	pathological	ADJ
bjos-8661512	236	23	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	236	24	.	.	PUNCT
bjos-8661512	237	1	cell	cell	NOUN
bjos-8661512	237	2	mol	mol	ADP
bjos-8661512	237	3	life	life	PROPN
bjos-8661512	237	4	sci	sci	PROPN
bjos-8661512	237	5	.	.	PUNCT
bjos-8661512	238	1	2018;75(14):2519	2018;75(14):2519	NUM
bjos-8661512	238	2	-	-	SYM
bjos-8661512	238	3	28	28	NUM
bjos-8661512	238	4	.	.	PUNCT
bjos-8661512	239	1	doi:10.1007	doi:10.1007	VERB
bjos-8661512	239	2	/	/	SYM
bjos-8661512	239	3	s00018	s00018	NOUN
bjos-8661512	239	4	-	-	PUNCT
bjos-8661512	239	5	018	018	NUM
bjos-8661512	239	6	-	-	PUNCT
bjos-8661512	239	7	2817	2817	NUM
bjos-8661512	239	8	-	-	SYM
bjos-8661512	239	9	9	9	NUM
bjos-8661512	239	10	.	.	NOUN
bjos-8661512	239	11	3	3	NUM
bjos-8661512	239	12	.	.	X
bjos-8661512	239	13	van’t	van’t	NUM
bjos-8661512	239	14	hof	hof	PROPN
bjos-8661512	239	15	rj	rj	PROPN
bjos-8661512	239	16	,	,	PUNCT
bjos-8661512	239	17	armour	armour	NOUN
bjos-8661512	239	18	kj	kj	PROPN
bjos-8661512	239	19	,	,	PUNCT
bjos-8661512	239	20	smith	smith	PROPN
bjos-8661512	239	21	lm	lm	PROPN
bjos-8661512	239	22	,	,	PUNCT
bjos-8661512	239	23	armour	armour	NOUN
bjos-8661512	239	24	ke	ke	PROPN
bjos-8661512	239	25	,	,	PUNCT
bjos-8661512	239	26	wei	wei	PROPN
bjos-8661512	239	27	xq	xq	PROPN
bjos-8661512	239	28	,	,	PUNCT
bjos-8661512	239	29	liew	liew	PROPN
bjos-8661512	239	30	fy	fy	PROPN
bjos-8661512	239	31	,	,	PUNCT
bjos-8661512	239	32	et	et	PROPN
bjos-8661512	239	33	al	al	PROPN
bjos-8661512	239	34	.	.	PROPN
bjos-8661512	239	35	requirement	requirement	NOUN
bjos-8661512	239	36	of	of	ADP
bjos-8661512	239	37	the	the	DET
bjos-8661512	239	38	inducible	inducible	ADJ
bjos-8661512	239	39	nitric	nitric	ADJ
bjos-8661512	239	40	oxide	oxide	NOUN
bjos-8661512	239	41	synthase	synthase	NOUN
bjos-8661512	239	42	pathway	pathway	NOUN
bjos-8661512	239	43	for	for	ADP
bjos-8661512	239	44	il-1	il-1	ADV
bjos-8661512	239	45	-	-	PUNCT
bjos-8661512	239	46	induced	induce	VERB
bjos-8661512	239	47	osteoclastic	osteoclastic	NOUN
bjos-8661512	239	48	bone	bone	NOUN
bjos-8661512	239	49	resorption	resorption	NOUN
bjos-8661512	239	50	.	.	PUNCT
bjos-8661512	240	1	proc	proc	PROPN
bjos-8661512	240	2	natl	natl	PROPN
bjos-8661512	240	3	acad	acad	PROPN
bjos-8661512	240	4	sci	sci	PROPN
bjos-8661512	240	5	u	u	PROPN
bjos-8661512	240	6	s	s	PROPN
bjos-8661512	240	7	a.	a.	NOUN
bjos-8661512	240	8	2000;97(14):7993	2000;97(14):7993	NUM
bjos-8661512	240	9	-	-	SYM
bjos-8661512	240	10	8	8	NUM
bjos-8661512	240	11	.	.	PUNCT
bjos-8661512	241	1	doi:10.1073	doi:10.1073	NOUN
bjos-8661512	241	2	/	/	SYM
bjos-8661512	241	3	pnas.130511497	pnas.130511497	PROPN
bjos-8661512	241	4	.	.	PROPN
bjos-8661512	241	5	4	4	NUM
bjos-8661512	241	6	.	.	PUNCT
bjos-8661512	241	7	kırzıoğlu	kırzıoğlu	PROPN
bjos-8661512	241	8	fy	fy	PROPN
bjos-8661512	241	9	,	,	PUNCT
bjos-8661512	241	10	özmen	özmen	PROPN
bjos-8661512	241	11	ö	ö	PROPN
bjos-8661512	241	12	,	,	PUNCT
bjos-8661512	241	13	doğan	doğan	ADJ
bjos-8661512	241	14	b	b	NUM
bjos-8661512	241	15	,	,	PUNCT
bjos-8661512	241	16	bulut	bulut	PROPN
bjos-8661512	241	17	mt	mt	PROPN
bjos-8661512	241	18	,	,	PUNCT
bjos-8661512	241	19	fentoğlu	fentoğlu	PROPN
bjos-8661512	241	20	ö	ö	PROPN
bjos-8661512	241	21	,	,	PUNCT
bjos-8661512	241	22	özdem	özdem	PROPN
bjos-8661512	241	23	m.	m.	NOUN
bjos-8661512	241	24	effects	effect	NOUN
bjos-8661512	241	25	of	of	ADP
bjos-8661512	241	26	rosuvastatin	rosuvastatin	NOUN
bjos-8661512	241	27	on	on	ADP
bjos-8661512	241	28	inducible	inducible	ADJ
bjos-8661512	241	29	nitric	nitric	ADJ
bjos-8661512	241	30	oxide	oxide	NOUN
bjos-8661512	241	31	synthase	synthase	NOUN
bjos-8661512	241	32	in	in	ADP
bjos-8661512	241	33	rats	rat	NOUN
bjos-8661512	241	34	with	with	ADP
bjos-8661512	241	35	hyperlipidaemia	hyperlipidaemia	NOUN
bjos-8661512	241	36	and	and	CCONJ
bjos-8661512	241	37	periodontitis	periodontitis	NOUN
bjos-8661512	241	38	.	.	PUNCT
bjos-8661512	242	1	j	j	PROPN
bjos-8661512	242	2	periodontal	periodontal	ADJ
bjos-8661512	242	3	res	re	NOUN
bjos-8661512	242	4	.	.	PUNCT
bjos-8661512	243	1	2018;53(2):258	2018;53(2):258	PROPN
bjos-8661512	243	2	-	-	SYM
bjos-8661512	243	3	66	66	NUM
bjos-8661512	243	4	.	.	PUNCT
bjos-8661512	244	1	doi:10.1111	doi:10.1111	PROPN
bjos-8661512	244	2	/	/	SYM
bjos-8661512	244	3	jre.12513	jre.12513	PROPN
bjos-8661512	244	4	.	.	NOUN
bjos-8661512	245	1	5	5	NUM
bjos-8661512	245	2	.	.	X
bjos-8661512	245	3	smiley	smiley	PROPN
bjos-8661512	245	4	cj	cj	PROPN
bjos-8661512	245	5	,	,	PUNCT
bjos-8661512	245	6	tracy	tracy	PROPN
bjos-8661512	245	7	sl	sl	PROPN
bjos-8661512	245	8	,	,	PUNCT
bjos-8661512	245	9	abt	abt	X
bjos-8661512	245	10	e	e	NOUN
bjos-8661512	245	11	,	,	PUNCT
bjos-8661512	245	12	michalowicz	michalowicz	NOUN
bjos-8661512	245	13	bs	bs	PROPN
bjos-8661512	245	14	,	,	PUNCT
bjos-8661512	245	15	john	john	PROPN
bjos-8661512	245	16	mt	mt	PROPN
bjos-8661512	245	17	,	,	PUNCT
bjos-8661512	245	18	gunsolley	gunsolley	PROPN
bjos-8661512	245	19	j	j	PROPN
bjos-8661512	245	20	,	,	PUNCT
bjos-8661512	245	21	et	et	PROPN
bjos-8661512	245	22	al	al	PROPN
bjos-8661512	245	23	.	.	PROPN
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bjos-8661512	245	25	-	-	PUNCT
bjos-8661512	245	26	based	base	VERB
bjos-8661512	245	27	clinical	clinical	ADJ
bjos-8661512	245	28	practice	practice	NOUN
bjos-8661512	245	29	guideline	guideline	NOUN
bjos-8661512	245	30	on	on	ADP
bjos-8661512	245	31	the	the	DET
bjos-8661512	245	32	nonsurgical	nonsurgical	ADJ
bjos-8661512	245	33	treatment	treatment	NOUN
bjos-8661512	245	34	of	of	ADP
bjos-8661512	245	35	chronic	chronic	ADJ
bjos-8661512	245	36	periodontitis	periodontitis	NOUN
bjos-8661512	245	37	by	by	ADP
bjos-8661512	245	38	means	mean	NOUN
bjos-8661512	245	39	of	of	ADP
bjos-8661512	245	40	scaling	scaling	NOUN
bjos-8661512	245	41	and	and	CCONJ
bjos-8661512	245	42	root	root	NOUN
bjos-8661512	245	43	planing	planing	NOUN
bjos-8661512	245	44	with	with	ADP
bjos-8661512	245	45	or	or	CCONJ
bjos-8661512	245	46	without	without	ADP
bjos-8661512	245	47	adjuncts	adjunct	NOUN
bjos-8661512	245	48	.	.	PUNCT
bjos-8661512	246	1	j	j	PROPN
bjos-8661512	246	2	am	be	AUX
bjos-8661512	246	3	dent	dent	ADJ
bjos-8661512	246	4	assoc	assoc	NOUN
bjos-8661512	246	5	.	.	PUNCT
bjos-8661512	247	1	2015;146(7):525	2015;146(7):525	X
bjos-8661512	247	2	-	-	SYM
bjos-8661512	247	3	35	35	NUM
bjos-8661512	247	4	.	.	PUNCT
bjos-8661512	248	1	doi:10.1016	doi:10.1016	PROPN
bjos-8661512	248	2	/	/	SYM
bjos-8661512	248	3	j.adaj.2015.01.026	j.adaj.2015.01.026	PROPN
bjos-8661512	248	4	.	.	PUNCT
bjos-8661512	249	1	6	6	NUM
bjos-8661512	249	2	.	.	X
bjos-8661512	249	3	figdor	figdor	PROPN
bjos-8661512	249	4	d.	d.	PROPN
bjos-8661512	249	5	microbial	microbial	PROPN
bjos-8661512	249	6	aetiology	aetiology	NOUN
bjos-8661512	249	7	of	of	ADP
bjos-8661512	249	8	endodontic	endodontic	ADJ
bjos-8661512	249	9	treatment	treatment	NOUN
bjos-8661512	249	10	failure	failure	NOUN
bjos-8661512	249	11	and	and	CCONJ
bjos-8661512	249	12	pathogenic	pathogenic	ADJ
bjos-8661512	249	13	properties	property	NOUN
bjos-8661512	249	14	of	of	ADP
bjos-8661512	249	15	selected	select	VERB
bjos-8661512	249	16	species	specie	NOUN
bjos-8661512	249	17	.	.	PUNCT
bjos-8661512	250	1	aust	aust	PROPN
bjos-8661512	250	2	endod	endod	PROPN
bjos-8661512	250	3	j.	j.	PROPN
bjos-8661512	250	4	2004;30(1):11	2004;30(1):11	PROPN
bjos-8661512	250	5	-	-	PUNCT
bjos-8661512	250	6	4	4	NUM
bjos-8661512	250	7	.	.	PUNCT
bjos-8661512	250	8	doi:10.1111	doi:10.1111	PROPN
bjos-8661512	250	9	/	/	SYM
bjos-8661512	250	10	j.1747	j.1747	PROPN
bjos-8661512	250	11	-	-	PUNCT
bjos-8661512	250	12	4477.2004.tb00159.x	4477.2004.tb00159.x	PROPN
bjos-8661512	250	13	.	.	PUNCT
bjos-8661512	251	1	7	7	X
bjos-8661512	251	2	.	.	X
bjos-8661512	251	3	gorr	gorr	PROPN
bjos-8661512	251	4	su	su	PROPN
bjos-8661512	251	5	,	,	PUNCT
bjos-8661512	251	6	abdolhosseini	abdolhosseini	NOUN
bjos-8661512	251	7	m.	m.	NOUN
bjos-8661512	251	8	antimicrobial	antimicrobial	ADJ
bjos-8661512	251	9	peptides	peptide	NOUN
bjos-8661512	251	10	and	and	CCONJ
bjos-8661512	251	11	periodontal	periodontal	ADJ
bjos-8661512	251	12	disease	disease	NOUN
bjos-8661512	251	13	.	.	PUNCT
bjos-8661512	252	1	j	j	PROPN
bjos-8661512	252	2	clin	clin	PROPN
bjos-8661512	252	3	periodontol	periodontol	PROPN
bjos-8661512	252	4	.	.	PUNCT
bjos-8661512	253	1	2011;38	2011;38	NUM
bjos-8661512	253	2	suppl	suppl	ADJ
bjos-8661512	253	3	11:126	11:126	NUM
bjos-8661512	253	4	-	-	SYM
bjos-8661512	253	5	41	41	NUM
bjos-8661512	253	6	.	.	PUNCT
bjos-8661512	254	1	doi:10.1111	doi:10.1111	ADJ
bjos-8661512	254	2	/	/	SYM
bjos-8661512	254	3	j.1600	j.1600	PROPN
bjos-8661512	254	4	-	-	PUNCT
bjos-8661512	254	5	051x.2010.01664.x	051x.2010.01664.x	PROPN
bjos-8661512	254	6	.	.	PUNCT
bjos-8661512	255	1	8	8	NUM
bjos-8661512	255	2	.	.	X
bjos-8661512	255	3	wimley	wimley	PROPN
bjos-8661512	255	4	wc	wc	AUX
bjos-8661512	255	5	.	.	PROPN
bjos-8661512	255	6	describing	describe	VERB
bjos-8661512	255	7	the	the	DET
bjos-8661512	255	8	mechanism	mechanism	NOUN
bjos-8661512	255	9	of	of	ADP
bjos-8661512	255	10	antimicrobial	antimicrobial	ADJ
bjos-8661512	255	11	peptide	peptide	NOUN
bjos-8661512	255	12	action	action	NOUN
bjos-8661512	255	13	with	with	ADP
bjos-8661512	255	14	the	the	DET
bjos-8661512	255	15	interfacial	interfacial	ADJ
bjos-8661512	255	16	activity	activity	NOUN
bjos-8661512	255	17	model	model	NOUN
bjos-8661512	255	18	.	.	PUNCT
bjos-8661512	256	1	acs	acs	PROPN
bjos-8661512	256	2	chem	chem	PROPN
bjos-8661512	256	3	biol	biol	PROPN
bjos-8661512	256	4	.	.	PUNCT
bjos-8661512	257	1	2010;5(10):905	2010;5(10):905	VERB
bjos-8661512	257	2	-	-	SYM
bjos-8661512	257	3	17	17	NUM
bjos-8661512	257	4	.	.	PUNCT
bjos-8661512	258	1	doi:10.1021	doi:10.1021	ADJ
bjos-8661512	258	2	/	/	SYM
bjos-8661512	258	3	cb1001558	cb1001558	PROPN
bjos-8661512	258	4	.	.	PUNCT
bjos-8661512	259	1	9	9	X
bjos-8661512	259	2	.	.	X
bjos-8661512	259	3	silva	silva	NOUN
bjos-8661512	259	4	on	on	ADV
bjos-8661512	259	5	,	,	PUNCT
bjos-8661512	259	6	fensterseifer	fensterseifer	PROPN
bjos-8661512	259	7	ic	ic	PROPN
bjos-8661512	259	8	,	,	PUNCT
bjos-8661512	259	9	rodrigues	rodrigues	PROPN
bjos-8661512	259	10	ea	ea	PROPN
bjos-8661512	259	11	,	,	PUNCT
bjos-8661512	259	12	holanda	holanda	PROPN
bjos-8661512	259	13	hh	hh	PROPN
bjos-8661512	259	14	,	,	PUNCT
bjos-8661512	259	15	novaes	novaes	PROPN
bjos-8661512	259	16	nr	nr	PROPN
bjos-8661512	259	17	,	,	PUNCT
bjos-8661512	259	18	cunha	cunha	PROPN
bjos-8661512	259	19	jp	jp	PROPN
bjos-8661512	259	20	,	,	PUNCT
bjos-8661512	259	21	et	et	PROPN
bjos-8661512	259	22	al	al	PROPN
bjos-8661512	259	23	.	.	PUNCT
bjos-8661512	260	1	clavanin	clavanin	PROPN
bjos-8661512	260	2	a	a	PRON
bjos-8661512	260	3	improves	improve	VERB
bjos-8661512	260	4	outcome	outcome	NOUN
bjos-8661512	260	5	of	of	ADP
bjos-8661512	260	6	complications	complication	NOUN
bjos-8661512	260	7	from	from	ADP
bjos-8661512	260	8	different	different	ADJ
bjos-8661512	260	9	bacterial	bacterial	ADJ
bjos-8661512	260	10	infections	infection	NOUN
bjos-8661512	260	11	.	.	PUNCT
bjos-8661512	261	1	antimicrob	antimicrob	PROPN
bjos-8661512	261	2	agents	agents	PROPN
bjos-8661512	261	3	chemother	chemother	PROPN
bjos-8661512	261	4	.	.	PUNCT
bjos-8661512	262	1	2015;59(3):1620	2015;59(3):1620	NUM
bjos-8661512	262	2	-	-	SYM
bjos-8661512	262	3	6	6	NUM
bjos-8661512	262	4	.	.	PUNCT
bjos-8661512	262	5	doi:10.1128	doi:10.1128	NOUN
bjos-8661512	262	6	/	/	SYM
bjos-8661512	262	7	aac.03732	aac.03732	NOUN
bjos-8661512	262	8	-	-	SYM
bjos-8661512	262	9	14	14	NUM
bjos-8661512	262	10	.	.	PUNCT
bjos-8661512	263	1	10	10	NUM
bjos-8661512	263	2	.	.	X
bjos-8661512	264	1	silva	silva	NOUN
bjos-8661512	264	2	on	on	ADP
bjos-8661512	264	3	,	,	PUNCT
bjos-8661512	264	4	de	de	X
bjos-8661512	264	5	la	la	X
bjos-8661512	264	6	fuente	fuente	PROPN
bjos-8661512	264	7	-	-	PUNCT
bjos-8661512	264	8	núñez	núñez	NOUN
bjos-8661512	264	9	c	c	NOUN
bjos-8661512	264	10	,	,	PUNCT
bjos-8661512	264	11	haney	haney	PROPN
bjos-8661512	264	12	ef	ef	PROPN
bjos-8661512	264	13	,	,	PUNCT
bjos-8661512	264	14	fensterseifer	fensterseifer	PROPN
bjos-8661512	264	15	ic	ic	PROPN
bjos-8661512	264	16	,	,	PUNCT
bjos-8661512	264	17	ribeiro	ribeiro	PROPN
bjos-8661512	264	18	sm	sm	PROPN
bjos-8661512	264	19	,	,	PUNCT
bjos-8661512	264	20	porto	porto	PROPN
bjos-8661512	264	21	wf	wf	PROPN
bjos-8661512	264	22	,	,	PUNCT
bjos-8661512	264	23	et	et	PROPN
bjos-8661512	264	24	al	al	PROPN
bjos-8661512	264	25	.	.	PUNCT
bjos-8661512	265	1	an	an	DET
bjos-8661512	265	2	anti	anti	ADJ
bjos-8661512	265	3	-	-	ADJ
bjos-8661512	265	4	infective	infective	ADJ
bjos-8661512	265	5	synthetic	synthetic	ADJ
bjos-8661512	265	6	peptide	peptide	NOUN
bjos-8661512	265	7	with	with	ADP
bjos-8661512	265	8	dual	dual	ADJ
bjos-8661512	265	9	antimicrobial	antimicrobial	ADJ
bjos-8661512	265	10	and	and	CCONJ
bjos-8661512	265	11	immunomodulatory	immunomodulatory	ADJ
bjos-8661512	265	12	activities	activity	NOUN
bjos-8661512	265	13	.	.	PUNCT
bjos-8661512	266	1	sci	sci	PROPN
bjos-8661512	266	2	rep	rep	PROPN
bjos-8661512	266	3	.	.	PROPN
bjos-8661512	266	4	2016	2016	NUM
bjos-8661512	266	5	nov	nov	NOUN
bjos-8661512	266	6	2;6:35465	2;6:35465	NUM
bjos-8661512	266	7	.	.	PUNCT
bjos-8661512	267	1	doi	doi	NOUN
bjos-8661512	267	2	:	:	PUNCT
bjos-8661512	267	3	10.1038	10.1038	NUM
bjos-8661512	267	4	/	/	SYM
bjos-8661512	267	5	srep35465	srep35465	NOUN
bjos-8661512	267	6	.	.	PROPN
bjos-8661512	268	1	11	11	NUM
bjos-8661512	268	2	.	.	PUNCT
bjos-8661512	269	1	supanchart	supanchart	PROPN
bjos-8661512	269	2	c	c	PROPN
bjos-8661512	269	3	,	,	PUNCT
bjos-8661512	269	4	thawanaphong	thawanaphong	NOUN
bjos-8661512	269	5	s	s	PART
bjos-8661512	269	6	,	,	PUNCT
bjos-8661512	269	7	makeudom	makeudom	PROPN
bjos-8661512	269	8	a	a	NOUN
bjos-8661512	269	9	,	,	PUNCT
bjos-8661512	269	10	bolscher	bolscher	ADV
bjos-8661512	269	11	jg	jg	PROPN
bjos-8661512	269	12	,	,	PUNCT
bjos-8661512	269	13	nazmi	nazmi	PROPN
bjos-8661512	269	14	k	k	NOUN
bjos-8661512	269	15	,	,	PUNCT
bjos-8661512	269	16	kornak	kornak	PROPN
bjos-8661512	269	17	u	u	PROPN
bjos-8661512	269	18	,	,	PUNCT
bjos-8661512	269	19	et	et	PROPN
bjos-8661512	269	20	al	al	PROPN
bjos-8661512	269	21	.	.	PUNCT
bjos-8661512	270	1	the	the	DET
bjos-8661512	270	2	antimicrobial	antimicrobial	ADJ
bjos-8661512	270	3	peptide	peptide	NOUN
bjos-8661512	270	4	,	,	PUNCT
bjos-8661512	270	5	ll-37	ll-37	NOUN
bjos-8661512	270	6	,	,	PUNCT
bjos-8661512	270	7	inhibits	inhibit	VERB
bjos-8661512	270	8	in	in	ADP
bjos-8661512	270	9	vitro	vitro	X
bjos-8661512	270	10	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	270	11	.	.	PUNCT
bjos-8661512	271	1	j	j	PROPN
bjos-8661512	271	2	dent	dent	NOUN
bjos-8661512	271	3	res	re	NOUN
bjos-8661512	271	4	.	.	PUNCT
bjos-8661512	272	1	2012;91(11):1071	2012;91(11):1071	NUM
bjos-8661512	272	2	-	-	SYM
bjos-8661512	272	3	7	7	NUM
bjos-8661512	272	4	.	.	PUNCT
bjos-8661512	272	5	doi:10.1177/0022034512460402	doi:10.1177/0022034512460402	NOUN
bjos-8661512	272	6	.	.	PUNCT
bjos-8661512	273	1	12	12	NUM
bjos-8661512	273	2	.	.	PUNCT
bjos-8661512	274	1	park	park	PROPN
bjos-8661512	274	2	oj	oj	PROPN
bjos-8661512	274	3	,	,	PUNCT
bjos-8661512	274	4	kim	kim	PROPN
bjos-8661512	274	5	j	j	PROPN
bjos-8661512	274	6	,	,	PUNCT
bjos-8661512	274	7	ahn	ahn	PROPN
bjos-8661512	274	8	kb	kb	PROPN
bjos-8661512	274	9	,	,	PUNCT
bjos-8661512	274	10	lee	lee	PROPN
bjos-8661512	274	11	jy	jy	PROPN
bjos-8661512	274	12	,	,	PUNCT
bjos-8661512	274	13	park	park	PROPN
bjos-8661512	274	14	yj	yj	PROPN
bjos-8661512	274	15	,	,	PUNCT
bjos-8661512	274	16	kum	kum	PROPN
bjos-8661512	274	17	ky	ky	PROPN
bjos-8661512	274	18	,	,	PUNCT
bjos-8661512	274	19	et	et	PROPN
bjos-8661512	274	20	al	al	PROPN
bjos-8661512	274	21	.	.	PUNCT
bjos-8661512	275	1	a	a	DET
bjos-8661512	275	2	15	15	NUM
bjos-8661512	275	3	-	-	PUNCT
bjos-8661512	275	4	amino	amino	NOUN
bjos-8661512	275	5	acid	acid	NOUN
bjos-8661512	275	6	c	c	NOUN
bjos-8661512	275	7	-	-	PUNCT
bjos-8661512	275	8	terminal	terminal	ADJ
bjos-8661512	275	9	peptide	peptide	NOUN
bjos-8661512	275	10	of	of	ADP
bjos-8661512	275	11	beta	beta	NOUN
bjos-8661512	275	12	-	-	PUNCT
bjos-8661512	275	13	defensin-3	defensin-3	NOUN
bjos-8661512	275	14	inhibits	inhibit	VERB
bjos-8661512	275	15	bone	bone	NOUN
bjos-8661512	275	16	resorption	resorption	NOUN
bjos-8661512	275	17	by	by	ADP
bjos-8661512	275	18	inhibiting	inhibit	VERB
bjos-8661512	275	19	the	the	DET
bjos-8661512	275	20	osteoclast	osteoclast	ADJ
bjos-8661512	275	21	differentiation	differentiation	NOUN
bjos-8661512	275	22	and	and	CCONJ
bjos-8661512	275	23	disrupting	disrupt	VERB
bjos-8661512	275	24	podosome	podosome	ADJ
bjos-8661512	275	25	belt	belt	NOUN
bjos-8661512	275	26	formation	formation	NOUN
bjos-8661512	275	27	.	.	PUNCT
bjos-8661512	276	1	j	j	PROPN
bjos-8661512	276	2	mol	mol	ADP
bjos-8661512	276	3	med	med	PROPN
bjos-8661512	276	4	(	(	PUNCT
bjos-8661512	276	5	berl	berl	PROPN
bjos-8661512	276	6	)	)	PUNCT
bjos-8661512	276	7	.	.	PUNCT
bjos-8661512	277	1	2017;95(12):1315	2017;95(12):1315	NUM
bjos-8661512	277	2	-	-	SYM
bjos-8661512	277	3	25	25	NUM
bjos-8661512	278	1	.	.	PUNCT
bjos-8661512	278	2	doi:10.1007	doi:10.1007	VERB
bjos-8661512	278	3	/	/	SYM
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bjos-8661512	278	5	-	-	PUNCT
bjos-8661512	278	6	017	017	NUM
bjos-8661512	278	7	-	-	PUNCT
bjos-8661512	278	8	1589	1589	NUM
bjos-8661512	278	9	-	-	SYM
bjos-8661512	278	10	2	2	NUM
bjos-8661512	278	11	.	.	NOUN
bjos-8661512	278	12	13	13	NUM
bjos-8661512	278	13	.	.	PUNCT
bjos-8661512	279	1	l	l	PROPN
bjos-8661512	279	2	lima	lima	PROPN
bjos-8661512	279	3	smf	smf	PROPN
bjos-8661512	279	4	,	,	PUNCT
bjos-8661512	279	5	freire	freire	PROPN
bjos-8661512	279	6	ms	ms	PROPN
bjos-8661512	279	7	,	,	PUNCT
bjos-8661512	279	8	cantuária	cantuária	PROPN
bjos-8661512	279	9	apc	apc	PROPN
bjos-8661512	279	10	,	,	PUNCT
bjos-8661512	279	11	martins	martin	VERB
bjos-8661512	279	12	dcm	dcm	PROPN
bjos-8661512	279	13	,	,	PUNCT
bjos-8661512	279	14	amorim	amorim	PROPN
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bjos-8661512	279	16	,	,	PUNCT
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bjos-8661512	279	19	,	,	PUNCT
bjos-8661512	279	20	et	et	PROPN
bjos-8661512	279	21	al	al	PROPN
bjos-8661512	279	22	.	.	PUNCT
bjos-8661512	280	1	the	the	DET
bjos-8661512	280	2	use	use	NOUN
bjos-8661512	280	3	of	of	ADP
bjos-8661512	280	4	host	host	NOUN
bjos-8661512	280	5	defense	defense	NOUN
bjos-8661512	280	6	peptides	peptide	NOUN
bjos-8661512	280	7	in	in	ADP
bjos-8661512	280	8	root	root	NOUN
bjos-8661512	280	9	canal	canal	NOUN
bjos-8661512	280	10	therapy	therapy	NOUN
bjos-8661512	280	11	in	in	ADP
bjos-8661512	280	12	rats	rat	NOUN
bjos-8661512	280	13	.	.	PUNCT
bjos-8661512	281	1	clin	clin	PROPN
bjos-8661512	281	2	oral	oral	PROPN
bjos-8661512	281	3	investig	investig	PROPN
bjos-8661512	281	4	.	.	PROPN
bjos-8661512	281	5	2020	2020	NUM
bjos-8661512	281	6	nov	nov	PROPN
bjos-8661512	281	7	16	16	NUM
bjos-8661512	281	8	.	.	PUNCT
bjos-8661512	282	1	doi	doi	NOUN
bjos-8661512	282	2	:	:	PUNCT
bjos-8661512	282	3	10.1007	10.1007	NUM
bjos-8661512	282	4	/	/	SYM
bjos-8661512	282	5	s00784	s00784	NOUN
bjos-8661512	282	6	-	-	PUNCT
bjos-8661512	282	7	020	020	NUM
bjos-8661512	282	8	-	-	PUNCT
bjos-8661512	282	9	03684	03684	NUM
bjos-8661512	282	10	-	-	PUNCT
bjos-8661512	282	11	9	9	NUM
bjos-8661512	282	12	.	.	NOUN
bjos-8661512	282	13	14	14	NUM
bjos-8661512	282	14	.	.	PUNCT
bjos-8661512	283	1	lima	lima	PROPN
bjos-8661512	283	2	smf	smf	PROPN
bjos-8661512	283	3	,	,	PUNCT
bjos-8661512	283	4	freire	freire	PROPN
bjos-8661512	283	5	ms	ms	PROPN
bjos-8661512	283	6	,	,	PUNCT
bjos-8661512	283	7	gomes	gomes	PROPN
bjos-8661512	283	8	alo	alo	PROPN
bjos-8661512	283	9	,	,	PUNCT
bjos-8661512	283	10	cantuária	cantuária	PROPN
bjos-8661512	283	11	apc	apc	PROPN
bjos-8661512	283	12	,	,	PUNCT
bjos-8661512	283	13	dutra	dutra	ADJ
bjos-8661512	283	14	frp	frp	PROPN
bjos-8661512	283	15	,	,	PUNCT
bjos-8661512	283	16	magalhães	magalhães	ADJ
bjos-8661512	283	17	bs	bs	PROPN
bjos-8661512	283	18	,	,	PUNCT
bjos-8661512	283	19	et	et	PROPN
bjos-8661512	283	20	al	al	PROPN
bjos-8661512	283	21	.	.	PROPN
bjos-8661512	283	22	antimicrobial	antimicrobial	ADJ
bjos-8661512	283	23	and	and	CCONJ
bjos-8661512	283	24	immunomodulatory	immunomodulatory	ADJ
bjos-8661512	283	25	activity	activity	NOUN
bjos-8661512	283	26	of	of	ADP
bjos-8661512	283	27	host	host	NOUN
bjos-8661512	283	28	defense	defense	NOUN
bjos-8661512	283	29	peptides	peptide	NOUN
bjos-8661512	283	30	,	,	PUNCT
bjos-8661512	283	31	clavanins	clavanin	NOUN
bjos-8661512	283	32	and	and	CCONJ
bjos-8661512	283	33	ll-37	ll-37	NOUN
bjos-8661512	283	34	,	,	PUNCT
bjos-8661512	283	35	in	in	ADP
bjos-8661512	283	36	vitro	vitro	NOUN
bjos-8661512	283	37	:	:	PUNCT
bjos-8661512	283	38	an	an	DET
bjos-8661512	283	39	endodontic	endodontic	ADJ
bjos-8661512	283	40	perspective	perspective	NOUN
bjos-8661512	283	41	.	.	PUNCT
bjos-8661512	284	1	peptides	peptide	NOUN
bjos-8661512	284	2	.	.	PUNCT
bjos-8661512	285	1	sep	sep	PROPN
bjos-8661512	285	2	2017;95:16	2017;95:16	NUM
bjos-8661512	285	3	-	-	PROPN
bjos-8661512	285	4	24	24	NUM
bjos-8661512	285	5	.	.	PUNCT
bjos-8661512	285	6	doi:10.1016	doi:10.1016	PROPN
bjos-8661512	285	7	/	/	SYM
bjos-8661512	285	8	j.peptides.2017.07.005	j.peptides.2017.07.005	PROPN
bjos-8661512	285	9	.	.	PUNCT
bjos-8661512	286	1	15	15	NUM
bjos-8661512	286	2	.	.	PUNCT
bjos-8661512	286	3	murphy	murphy	PROPN
bjos-8661512	286	4	jb	jb	PROPN
bjos-8661512	286	5	,	,	PUNCT
bjos-8661512	286	6	kies	kies	PROPN
bjos-8661512	286	7	mw	mw	PROPN
bjos-8661512	286	8	.	.	PROPN
bjos-8661512	286	9	note	note	NOUN
bjos-8661512	286	10	on	on	ADP
bjos-8661512	286	11	the	the	DET
bjos-8661512	286	12	spectrophotometric	spectrophotometric	ADJ
bjos-8661512	286	13	determination	determination	NOUN
bjos-8661512	286	14	of	of	ADP
bjos-8661512	286	15	proteins	protein	NOUN
bjos-8661512	286	16	in	in	ADP
bjos-8661512	286	17	dilute	dilute	ADJ
bjos-8661512	286	18	solutions	solution	NOUN
bjos-8661512	286	19	.	.	PUNCT
bjos-8661512	287	1	biochim	biochim	PROPN
bjos-8661512	287	2	biophys	biophy	NOUN
bjos-8661512	287	3	acta	acta	PROPN
bjos-8661512	287	4	.	.	PUNCT
bjos-8661512	287	5	 	 	SPACE
bjos-8661512	288	1	1960;45:382	1960;45:382	NUM
bjos-8661512	288	2	-	-	SYM
bjos-8661512	288	3	4	4	NUM
bjos-8661512	288	4	.	.	PUNCT
bjos-8661512	288	5	doi	doi	NOUN
bjos-8661512	288	6	:	:	PUNCT
bjos-8661512	288	7	10.1016/0006	10.1016/0006	NUM
bjos-8661512	288	8	-	-	PUNCT
bjos-8661512	288	9	3002(60)91464	3002(60)91464	NUM
bjos-8661512	288	10	-	-	PUNCT
bjos-8661512	288	11	5	5	NUM
bjos-8661512	288	12	.	.	NOUN
bjos-8661512	288	13	16	16	NUM
bjos-8661512	288	14	.	.	PUNCT
bjos-8661512	289	1	raschke	raschke	PROPN
bjos-8661512	289	2	wc	wc	PROPN
bjos-8661512	289	3	,	,	PUNCT
bjos-8661512	289	4	baird	baird	PROPN
bjos-8661512	289	5	s	s	PROPN
bjos-8661512	289	6	,	,	PUNCT
bjos-8661512	289	7	ralph	ralph	PROPN
bjos-8661512	289	8	p	p	X
bjos-8661512	289	9	,	,	PUNCT
bjos-8661512	289	10	nakoinz	nakoinz	PROPN
bjos-8661512	289	11	i.	i.	PROPN
bjos-8661512	289	12	functional	functional	ADJ
bjos-8661512	289	13	macrophage	macrophage	ADJ
bjos-8661512	289	14	cell	cell	NOUN
bjos-8661512	289	15	lines	line	NOUN
bjos-8661512	289	16	transformed	transform	VERB
bjos-8661512	289	17	by	by	ADP
bjos-8661512	289	18	abelson	abelson	PROPN
bjos-8661512	289	19	leukemia	leukemia	PROPN
bjos-8661512	289	20	virus	virus	NOUN
bjos-8661512	289	21	.	.	PUNCT
bjos-8661512	290	1	cell	cell	NOUN
bjos-8661512	290	2	.	.	PUNCT
bjos-8661512	291	1	1978;15(1):261	1978;15(1):261	NUM
bjos-8661512	291	2	-	-	SYM
bjos-8661512	291	3	7	7	NUM
bjos-8661512	291	4	.	.	PUNCT
bjos-8661512	291	5	doi:10.1016/0092	doi:10.1016/0092	PROPN
bjos-8661512	291	6	-	-	PUNCT
bjos-8661512	291	7	8674(78)90101	8674(78)90101	NUM
bjos-8661512	291	8	-	-	PUNCT
bjos-8661512	291	9	0	0	NUM
bjos-8661512	291	10	.	.	PROPN
bjos-8661512	291	11	17	17	NUM
bjos-8661512	291	12	.	.	PUNCT
bjos-8661512	292	1	van	van	PROPN
bjos-8661512	292	2	de	de	PROPN
bjos-8661512	292	3	loosdrecht	loosdrecht	PROPN
bjos-8661512	292	4	aa	aa	PROPN
bjos-8661512	292	5	,	,	PUNCT
bjos-8661512	292	6	nennie	nennie	PROPN
bjos-8661512	292	7	e	e	PROPN
bjos-8661512	292	8	,	,	PUNCT
bjos-8661512	292	9	ossenkoppele	ossenkoppele	PROPN
bjos-8661512	292	10	gj	gj	PROPN
bjos-8661512	292	11	,	,	PUNCT
bjos-8661512	292	12	beelen	beelen	PROPN
bjos-8661512	292	13	rh	rh	PROPN
bjos-8661512	292	14	,	,	PUNCT
bjos-8661512	292	15	langenhuijsen	langenhuijsen	VERB
bjos-8661512	292	16	mm	mm	PROPN
bjos-8661512	292	17	.	.	PUNCT
bjos-8661512	292	18	cell	cell	NOUN
bjos-8661512	292	19	mediated	mediate	VERB
bjos-8661512	292	20	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	292	21	against	against	ADP
bjos-8661512	292	22	u	u	NOUN
bjos-8661512	292	23	937	937	NUM
bjos-8661512	292	24	cells	cell	NOUN
bjos-8661512	292	25	by	by	ADP
bjos-8661512	292	26	human	human	ADJ
bjos-8661512	292	27	monocytes	monocyte	NOUN
bjos-8661512	292	28	and	and	CCONJ
bjos-8661512	292	29	macrophages	macrophage	NOUN
bjos-8661512	292	30	in	in	ADP
bjos-8661512	292	31	a	a	DET
bjos-8661512	292	32	modified	modify	VERB
bjos-8661512	292	33	colorimetric	colorimetric	ADJ
bjos-8661512	292	34	mtt	mtt	NOUN
bjos-8661512	292	35	assay	assay	VERB
bjos-8661512	292	36	.	.	PUNCT
bjos-8661512	293	1	a	a	DET
bjos-8661512	293	2	methodological	methodological	ADJ
bjos-8661512	293	3	study	study	NOUN
bjos-8661512	293	4	.	.	PUNCT
bjos-8661512	294	1	j	j	PROPN
bjos-8661512	294	2	immunol	immunol	NOUN
bjos-8661512	294	3	methods	method	NOUN
bjos-8661512	294	4	.	.	PUNCT
bjos-8661512	295	1	1991;141(1):15	1991;141(1):15	NUM
bjos-8661512	295	2	-	-	SYM
bjos-8661512	295	3	22	22	NUM
bjos-8661512	295	4	.	.	PUNCT
bjos-8661512	296	1	doi:10.1016/0022	doi:10.1016/0022	NOUN
bjos-8661512	296	2	-	-	PUNCT
bjos-8661512	296	3	1759(91)90205	1759(91)90205	NUM
bjos-8661512	296	4	-	-	PUNCT
bjos-8661512	296	5	t.	t.	ADJ
bjos-8661512	296	6	18	18	NUM
bjos-8661512	296	7	.	.	PUNCT
bjos-8661512	296	8	green	green	PROPN
bjos-8661512	296	9	lc	lc	PROPN
bjos-8661512	296	10	,	,	PUNCT
bjos-8661512	296	11	wagner	wagner	PROPN
bjos-8661512	296	12	da	da	PROPN
bjos-8661512	296	13	,	,	PUNCT
bjos-8661512	296	14	glogowski	glogowski	PROPN
bjos-8661512	296	15	j	j	PROPN
bjos-8661512	296	16	,	,	PUNCT
bjos-8661512	296	17	skipper	skipper	PROPN
bjos-8661512	296	18	pl	pl	PROPN
bjos-8661512	296	19	,	,	PUNCT
bjos-8661512	296	20	wishnok	wishnok	NOUN
bjos-8661512	296	21	js	js	PROPN
bjos-8661512	296	22	,	,	PUNCT
bjos-8661512	296	23	tannenbaum	tannenbaum	PROPN
bjos-8661512	296	24	sr	sr	PROPN
bjos-8661512	296	25	.	.	PUNCT
bjos-8661512	297	1	analysis	analysis	NOUN
bjos-8661512	297	2	of	of	ADP
bjos-8661512	297	3	nitrate	nitrate	NOUN
bjos-8661512	297	4	,	,	PUNCT
bjos-8661512	297	5	nitrite	nitrite	NOUN
bjos-8661512	297	6	,	,	PUNCT
bjos-8661512	297	7	and	and	CCONJ
bjos-8661512	297	8	[	[	X
bjos-8661512	297	9	15n]nitrate	15n]nitrate	NOUN
bjos-8661512	297	10	in	in	ADP
bjos-8661512	297	11	biological	biological	ADJ
bjos-8661512	297	12	fluids	fluid	NOUN
bjos-8661512	297	13	.	.	PUNCT
bjos-8661512	298	1	anal	anal	ADJ
bjos-8661512	298	2	biochem	biochem	PROPN
bjos-8661512	298	3	.	.	PUNCT
bjos-8661512	299	1	oct	oct	PROPN
bjos-8661512	299	2	1982;126(1):131	1982;126(1):131	NUM
bjos-8661512	299	3	-	-	SYM
bjos-8661512	299	4	8	8	NUM
bjos-8661512	299	5	.	.	PUNCT
bjos-8661512	299	6	doi:10.1016/0003	doi:10.1016/0003	VERB
bjos-8661512	299	7	-	-	PUNCT
bjos-8661512	299	8	2697(82)90118	2697(82)90118	NUM
bjos-8661512	299	9	-	-	PUNCT
bjos-8661512	299	10	x.	x.	NOUN
bjos-8661512	299	11	12	12	NUM
bjos-8661512	299	12	amorim	amorim	PROPN
bjos-8661512	299	13	et	et	PROPN
bjos-8661512	299	14	al	al	PROPN
bjos-8661512	299	15	.	.	PROPN
bjos-8661512	299	16	19	19	NUM
bjos-8661512	299	17	.	.	PUNCT
bjos-8661512	300	1	lima	lima	PROPN
bjos-8661512	300	2	smf	smf	PROPN
bjos-8661512	300	3	,	,	PUNCT
bjos-8661512	300	4	de	de	PROPN
bjos-8661512	300	5	pádua	pádua	PROPN
bjos-8661512	300	6	gm	gm	PROPN
bjos-8661512	300	7	,	,	PUNCT
bjos-8661512	300	8	sousa	sousa	PROPN
bjos-8661512	300	9	mgdc	mgdc	PROPN
bjos-8661512	300	10	,	,	PUNCT
bjos-8661512	300	11	freire	freire	PROPN
bjos-8661512	300	12	ms	ms	PROPN
bjos-8661512	300	13	,	,	PUNCT
bjos-8661512	300	14	franco	franco	PROPN
bjos-8661512	300	15	ol	ol	PROPN
bjos-8661512	300	16	,	,	PUNCT
bjos-8661512	300	17	rezende	rezende	PROPN
bjos-8661512	300	18	tmb	tmb	PROPN
bjos-8661512	300	19	.	.	PUNCT
bjos-8661512	300	20	antimicrobial	antimicrobial	ADJ
bjos-8661512	300	21	peptide	peptide	NOUN
bjos-8661512	300	22	-	-	PUNCT
bjos-8661512	300	23	based	base	VERB
bjos-8661512	300	24	treatment	treatment	NOUN
bjos-8661512	300	25	for	for	ADP
bjos-8661512	300	26	endodontic	endodontic	ADJ
bjos-8661512	300	27	infections	infection	NOUN
bjos-8661512	300	28	--	--	PUNCT
bjos-8661512	300	29	biotechnological	biotechnological	ADJ
bjos-8661512	300	30	innovation	innovation	NOUN
bjos-8661512	300	31	in	in	ADP
bjos-8661512	300	32	endodontics	endodontic	NOUN
bjos-8661512	300	33	.	.	PUNCT
bjos-8661512	301	1	biotechnol	biotechnol	PROPN
bjos-8661512	301	2	adv	adv	PROPN
bjos-8661512	301	3	.	.	PROPN
bjos-8661512	301	4	2015	2015	NUM
bjos-8661512	301	5	jan	jan	PROPN
bjos-8661512	301	6	-	-	PUNCT
bjos-8661512	301	7	feb	feb	PROPN
bjos-8661512	301	8	2015;33(1):203	2015;33(1):203	NUM
bjos-8661512	301	9	-	-	SYM
bjos-8661512	301	10	13	13	NUM
bjos-8661512	301	11	.	.	PUNCT
bjos-8661512	302	1	doi:10.1016	doi:10.1016	PROPN
bjos-8661512	302	2	/	/	SYM
bjos-8661512	302	3	j.biotechadv.2014.10.013	j.biotechadv.2014.10.013	PROPN
bjos-8661512	302	4	.	.	PROPN
bjos-8661512	303	1	20	20	NUM
bjos-8661512	303	2	.	.	PUNCT
bjos-8661512	303	3	mandal	mandal	PROPN
bjos-8661512	303	4	sm	sm	PROPN
bjos-8661512	303	5	,	,	PUNCT
bjos-8661512	303	6	khan	khan	PROPN
bjos-8661512	303	7	j	j	PROPN
bjos-8661512	303	8	,	,	PUNCT
bjos-8661512	303	9	mahata	mahata	VERB
bjos-8661512	303	10	d	d	PROPN
bjos-8661512	303	11	,	,	PUNCT
bjos-8661512	303	12	saha	saha	PROPN
bjos-8661512	303	13	s	s	PROPN
bjos-8661512	303	14	,	,	PUNCT
bjos-8661512	303	15	sengupta	sengupta	PROPN
bjos-8661512	303	16	j	j	PROPN
bjos-8661512	303	17	,	,	PUNCT
bjos-8661512	303	18	silva	silva	NOUN
bjos-8661512	303	19	on	on	ADP
bjos-8661512	303	20	,	,	PUNCT
bjos-8661512	303	21	et	et	PROPN
bjos-8661512	303	22	al	al	PROPN
bjos-8661512	303	23	.	.	PUNCT
bjos-8661512	304	1	a	a	DET
bjos-8661512	304	2	self	self	NOUN
bjos-8661512	304	3	-	-	PUNCT
bjos-8661512	304	4	assembled	assemble	VERB
bjos-8661512	304	5	clavanin	clavanin	NOUN
bjos-8661512	304	6	a	a	PRON
bjos-8661512	304	7	-	-	PUNCT
bjos-8661512	304	8	coated	coated	ADJ
bjos-8661512	304	9	amniotic	amniotic	ADJ
bjos-8661512	304	10	membrane	membrane	NOUN
bjos-8661512	304	11	scaffold	scaffold	NOUN
bjos-8661512	304	12	for	for	ADP
bjos-8661512	304	13	the	the	DET
bjos-8661512	304	14	prevention	prevention	NOUN
bjos-8661512	304	15	of	of	ADP
bjos-8661512	304	16	biofilm	biofilm	NOUN
bjos-8661512	304	17	formation	formation	NOUN
bjos-8661512	304	18	by	by	ADP
bjos-8661512	304	19	ocular	ocular	ADJ
bjos-8661512	304	20	surface	surface	NOUN
bjos-8661512	304	21	fungal	fungal	ADJ
bjos-8661512	304	22	pathogens	pathogen	NOUN
bjos-8661512	304	23	.	.	PUNCT
bjos-8661512	305	1	biofouling	biofoule	VERB
bjos-8661512	305	2	.	.	PUNCT
bjos-8661512	306	1	2017	2017	NUM
bjos-8661512	306	2	nov;33(10):881	nov;33(10):881	NUM
bjos-8661512	306	3	-	-	PUNCT
bjos-8661512	306	4	891	891	NUM
bjos-8661512	306	5	.	.	PUNCT
bjos-8661512	307	1	doi	doi	NOUN
bjos-8661512	307	2	:	:	PUNCT
bjos-8661512	307	3	10.1080/08927014.2017.1383400	10.1080/08927014.2017.1383400	NUM
bjos-8661512	307	4	.	.	NOUN
bjos-8661512	308	1	21	21	NUM
bjos-8661512	308	2	.	.	PUNCT
bjos-8661512	309	1	wang	wang	PROPN
bjos-8661512	309	2	fs	fs	PROPN
bjos-8661512	309	3	,	,	PUNCT
bjos-8661512	309	4	wang	wang	PROPN
bjos-8661512	309	5	cj	cj	PROPN
bjos-8661512	309	6	,	,	PUNCT
bjos-8661512	309	7	chen	chen	PROPN
bjos-8661512	309	8	yj	yj	PROPN
bjos-8661512	309	9	,	,	PUNCT
bjos-8661512	309	10	huang	huang	PROPN
bjos-8661512	309	11	yt	yt	PROPN
bjos-8661512	309	12	,	,	PUNCT
bjos-8661512	309	13	huang	huang	PROPN
bjos-8661512	309	14	hc	hc	PROPN
bjos-8661512	309	15	,	,	PUNCT
bjos-8661512	309	16	chang	chang	PROPN
bjos-8661512	309	17	pr	pr	PROPN
bjos-8661512	309	18	,	,	PUNCT
bjos-8661512	309	19	et	et	PROPN
bjos-8661512	309	20	al	al	PROPN
bjos-8661512	309	21	.	.	PROPN
bjos-8661512	309	22	nitric	nitric	ADJ
bjos-8661512	309	23	oxide	oxide	NOUN
bjos-8661512	309	24	donor	donor	NOUN
bjos-8661512	309	25	increases	increase	VERB
bjos-8661512	309	26	osteoprotegerin	osteoprotegerin	NOUN
bjos-8661512	309	27	production	production	NOUN
bjos-8661512	309	28	and	and	CCONJ
bjos-8661512	309	29	osteoclastogenesis	osteoclastogenesis	NOUN
bjos-8661512	309	30	inhibitory	inhibitory	ADJ
bjos-8661512	309	31	activity	activity	NOUN
bjos-8661512	309	32	in	in	ADP
bjos-8661512	309	33	bone	bone	NOUN
bjos-8661512	309	34	marrow	marrow	NOUN
bjos-8661512	309	35	stromal	stromal	ADJ
bjos-8661512	309	36	cells	cell	NOUN
bjos-8661512	309	37	from	from	ADP
bjos-8661512	309	38	ovariectomized	ovariectomize	VERB
bjos-8661512	309	39	rats	rat	NOUN
bjos-8661512	309	40	.	.	PUNCT
bjos-8661512	310	1	endocrinology	endocrinology	NOUN
bjos-8661512	310	2	.	.	PUNCT
bjos-8661512	311	1	2004;145(5):2148	2004;145(5):2148	NUM
bjos-8661512	311	2	-	-	SYM
bjos-8661512	311	3	56	56	NUM
bjos-8661512	311	4	.	.	PUNCT
bjos-8661512	312	1	doi:10.1210	doi:10.1210	PROPN
bjos-8661512	312	2	/	/	SYM
bjos-8661512	312	3	en.2003	en.2003	PROPN
bjos-8661512	312	4	-	-	PROPN
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bjos-8661512	312	6	.	.	PUNCT
bjos-8661512	313	1	22	22	NUM
bjos-8661512	313	2	.	.	PUNCT
bjos-8661512	314	1	vieira	vieira	PROPN
bjos-8661512	314	2	gha	gha	PROPN
bjos-8661512	314	3	,	,	PUNCT
bjos-8661512	314	4	messora	messora	PROPN
bjos-8661512	314	5	mr	mr	PROPN
bjos-8661512	314	6	,	,	PUNCT
bjos-8661512	314	7	moura	moura	PROPN
bjos-8661512	314	8	jmt	jmt	PROPN
bjos-8661512	314	9	,	,	PUNCT
bjos-8661512	314	10	fernandes	fernandes	PROPN
bjos-8661512	314	11	pg	pg	PROPN
bjos-8661512	314	12	,	,	PUNCT
bjos-8661512	314	13	furlaneto	furlaneto	PROPN
bjos-8661512	314	14	fac	fac	PROPN
bjos-8661512	314	15	,	,	PUNCT
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bjos-8661512	314	17	db	db	PROPN
bjos-8661512	314	18	,	,	PUNCT
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bjos-8661512	314	21	.	.	PUNCT
bjos-8661512	315	1	sub	sub	ADJ
bjos-8661512	315	2	-	-	ADJ
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bjos-8661512	315	5	of	of	ADP
bjos-8661512	315	6	doxycycline	doxycycline	NOUN
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bjos-8661512	315	8	bone	bone	NOUN
bjos-8661512	315	9	loss	loss	NOUN
bjos-8661512	315	10	related	relate	VERB
bjos-8661512	315	11	to	to	ADP
bjos-8661512	315	12	ligature	ligature	NOUN
bjos-8661512	315	13	-	-	PUNCT
bjos-8661512	315	14	induced	induce	VERB
bjos-8661512	315	15	periodontitis	periodontitis	NOUN
bjos-8661512	315	16	in	in	ADP
bjos-8661512	315	17	hypertensive	hypertensive	ADJ
bjos-8661512	315	18	rats	rat	NOUN
bjos-8661512	315	19	.	.	PUNCT
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bjos-8661512	316	2	oral	oral	ADJ
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bjos-8661512	316	4	.	.	PUNCT
bjos-8661512	317	1	2019;101:77	2019;101:77	NUM
bjos-8661512	317	2	-	-	SYM
bjos-8661512	317	3	84	84	NUM
bjos-8661512	317	4	.	.	PUNCT
bjos-8661512	318	1	doi:10.1016	doi:10.1016	PROPN
bjos-8661512	318	2	/	/	SYM
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bjos-8661512	318	4	.	.	PUNCT
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bjos-8661512	319	2	.	.	PUNCT
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bjos-8661512	320	6	,	,	PUNCT
bjos-8661512	320	7	okamura	okamura	PRON
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bjos-8661512	320	9	,	,	PUNCT
bjos-8661512	320	10	teramachi	teramachi	PROPN
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bjos-8661512	320	12	,	,	PUNCT
bjos-8661512	320	13	ochiai	ochiai	PROPN
bjos-8661512	320	14	k	k	PROPN
bjos-8661512	320	15	,	,	PUNCT
bjos-8661512	320	16	qiu	qiu	PROPN
bjos-8661512	320	17	l	l	PROPN
bjos-8661512	320	18	,	,	PUNCT
bjos-8661512	320	19	et	et	PROPN
bjos-8661512	320	20	al	al	PROPN
bjos-8661512	320	21	.	.	PROPN
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bjos-8661512	320	23	hydroxide	hydroxide	NOUN
bjos-8661512	320	24	suppresses	suppress	VERB
bjos-8661512	320	25	porphyromonas	porphyromona	NOUN
bjos-8661512	320	26	endodontalis	endodontali	VERB
bjos-8661512	320	27	lipopolysaccharide	lipopolysaccharide	ADV
bjos-8661512	320	28	-	-	PUNCT
bjos-8661512	320	29	induced	induce	VERB
bjos-8661512	320	30	bone	bone	NOUN
bjos-8661512	320	31	destruction	destruction	NOUN
bjos-8661512	320	32	.	.	PUNCT
bjos-8661512	321	1	j	j	PROPN
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bjos-8661512	321	4	.	.	PUNCT
bjos-8661512	322	1	2014;93(5):508	2014;93(5):508	NUM
bjos-8661512	322	2	-	-	SYM
bjos-8661512	322	3	13	13	NUM
bjos-8661512	322	4	.	.	PUNCT
bjos-8661512	323	1	doi:10.1177/0022034514526886	doi:10.1177/0022034514526886	NOUN
bjos-8661512	323	2	.	.	PUNCT
bjos-8661512	324	1	24	24	NUM
bjos-8661512	324	2	.	.	PUNCT
bjos-8661512	325	1	modena	modena	PROPN
bjos-8661512	325	2	kc	kc	PROPN
bjos-8661512	325	3	,	,	PUNCT
bjos-8661512	325	4	casas	casas	PROPN
bjos-8661512	325	5	-	-	PUNCT
bjos-8661512	325	6	apayco	apayco	PROPN
bjos-8661512	325	7	lc	lc	NOUN
bjos-8661512	325	8	,	,	PUNCT
bjos-8661512	325	9	atta	atta	PROPN
bjos-8661512	325	10	mt	mt	PROPN
bjos-8661512	325	11	,	,	PUNCT
bjos-8661512	325	12	costa	costa	PROPN
bjos-8661512	325	13	ca	can	AUX
bjos-8661512	325	14	,	,	PUNCT
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bjos-8661512	325	16	j	j	PROPN
bjos-8661512	325	17	,	,	PUNCT
bjos-8661512	325	18	sipert	sipert	PROPN
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bjos-8661512	325	20	,	,	PUNCT
bjos-8661512	325	21	et	et	PROPN
bjos-8661512	325	22	al	al	PROPN
bjos-8661512	325	23	.	.	PROPN
bjos-8661512	325	24	cytotoxicity	cytotoxicity	NOUN
bjos-8661512	325	25	and	and	CCONJ
bjos-8661512	325	26	biocompatibility	biocompatibility	NOUN
bjos-8661512	325	27	of	of	ADP
bjos-8661512	325	28	direct	direct	ADJ
bjos-8661512	325	29	and	and	CCONJ
bjos-8661512	325	30	indirect	indirect	ADJ
bjos-8661512	325	31	pulp	pulp	NOUN
bjos-8661512	325	32	capping	cap	VERB
bjos-8661512	325	33	materials	material	NOUN
bjos-8661512	325	34	.	.	PUNCT
bjos-8661512	326	1	j	j	PROPN
bjos-8661512	326	2	appl	appl	PROPN
bjos-8661512	326	3	oral	oral	PROPN
bjos-8661512	326	4	sci	sci	PROPN
bjos-8661512	326	5	.	.	PUNCT
bjos-8661512	327	1	2009;17(6):544	2009;17(6):544	NUM
bjos-8661512	327	2	-	-	SYM
bjos-8661512	327	3	54	54	NUM
bjos-8661512	327	4	.	.	PUNCT
bjos-8661512	328	1	doi:10.1590	doi:10.1590	ADJ
bjos-8661512	328	2	/	/	SYM
bjos-8661512	328	3	s1678	s1678	NOUN
bjos-8661512	328	4	-	-	NOUN
bjos-8661512	328	5	77572009000600002	77572009000600002	NUM
bjos-8661512	328	6	.	.	PUNCT