id	sid	tid	token	lemma	pos
bjos-8668749	1	1	1	1	NUM
bjos-8668749	1	2	volume	volume	NOUN
bjos-8668749	1	3	22	22	NUM
bjos-8668749	1	4	2023	2023	NUM
bjos-8668749	1	5	e238749	e238749	NOUN
bjos-8668749	1	6	original	original	ADJ
bjos-8668749	1	7	article	article	NOUN
bjos-8668749	1	8	braz	braz	PROPN
bjos-8668749	1	9	j	j	PROPN
bjos-8668749	1	10	oral	oral	PROPN
bjos-8668749	1	11	sci	sci	PROPN
bjos-8668749	1	12	.	.	PUNCT
bjos-8668749	2	1	2023;22	2023;22	NUM
bjos-8668749	2	2	:	:	PUNCT
bjos-8668749	2	3	e238749http://dx.doi.org/10.20396	e238749http://dx.doi.org/10.20396	SYM
bjos-8668749	2	4	/	/	SYM
bjos-8668749	2	5	bjos.v22i00.8668749	bjos.v22i00.8668749	NOUN
bjos-8668749	2	6	1	1	NUM
bjos-8668749	2	7	department	department	NOUN
bjos-8668749	2	8	of	of	ADP
bjos-8668749	2	9	materials	material	NOUN
bjos-8668749	2	10	sciences	science	NOUN
bjos-8668749	2	11	,	,	PUNCT
bjos-8668749	2	12	military	military	NOUN
bjos-8668749	2	13	institute	institute	PROPN
bjos-8668749	2	14	of	of	ADP
bjos-8668749	2	15	engineering	engineering	PROPN
bjos-8668749	2	16	,	,	PUNCT
bjos-8668749	2	17	rio	rio	PROPN
bjos-8668749	2	18	de	de	PROPN
bjos-8668749	2	19	janeiro	janeiro	PROPN
bjos-8668749	2	20	,	,	PUNCT
bjos-8668749	2	21	rj	rj	PROPN
bjos-8668749	2	22	,	,	PUNCT
bjos-8668749	2	23	brazil	brazil	PROPN
bjos-8668749	2	24	.	.	PUNCT
bjos-8668749	3	1	corresponding	correspond	VERB
bjos-8668749	3	2	author	author	NOUN
bjos-8668749	3	3	:	:	PUNCT
bjos-8668749	3	4	carlos	carlos	PROPN
bjos-8668749	3	5	nelson	nelson	PROPN
bjos-8668749	3	6	elias	elias	PROPN
bjos-8668749	3	7	military	military	PROPN
bjos-8668749	3	8	institute	institute	PROPN
bjos-8668749	3	9	of	of	ADP
bjos-8668749	3	10	engineering	engineering	PROPN
bjos-8668749	3	11	pr	pr	ADP
bjos-8668749	3	12	gen	gen	PROPN
bjos-8668749	3	13	tibúruco	tibúruco	NOUN
bjos-8668749	3	14	,	,	PUNCT
bjos-8668749	3	15	80	80	NUM
bjos-8668749	3	16	rio	rio	PROPN
bjos-8668749	3	17	de	de	PROPN
bjos-8668749	3	18	janeiro	janeiro	PROPN
bjos-8668749	3	19	,	,	PUNCT
bjos-8668749	3	20	rj	rj	PROPN
bjos-8668749	3	21	22290	22290	NUM
bjos-8668749	3	22	-	-	PUNCT
bjos-8668749	3	23	270	270	NUM
bjos-8668749	3	24	elias@ime.eb.br	elias@ime.eb.br	ADJ
bjos-8668749	3	25	editor	editor	NOUN
bjos-8668749	3	26	:	:	PUNCT
bjos-8668749	3	27	altair	altair	PROPN
bjos-8668749	3	28	a.	a.	PROPN
bjos-8668749	3	29	del	del	PROPN
bjos-8668749	3	30	bel	bel	PROPN
bjos-8668749	3	31	cury	cury	PROPN
bjos-8668749	3	32	received	receive	VERB
bjos-8668749	3	33	:	:	PUNCT
bjos-8668749	3	34	mar	mar	PROPN
bjos-8668749	3	35	24	24	NUM
bjos-8668749	3	36	,	,	PUNCT
bjos-8668749	3	37	2022	2022	NUM
bjos-8668749	3	38	accepted	accept	VERB
bjos-8668749	3	39	:	:	PUNCT
bjos-8668749	3	40	jan	jan	PROPN
bjos-8668749	3	41	15	15	NUM
bjos-8668749	3	42	,	,	PUNCT
bjos-8668749	3	43	2023	2023	NUM
bjos-8668749	3	44	protein	protein	NOUN
bjos-8668749	3	45	interactions	interaction	NOUN
bjos-8668749	3	46	with	with	ADP
bjos-8668749	3	47	osseointegrable	osseointegrable	ADJ
bjos-8668749	3	48	titanium	titanium	NOUN
bjos-8668749	3	49	implants	implant	NOUN
bjos-8668749	3	50	marvin	marvin	PROPN
bjos-8668749	3	51	do	do	AUX
bjos-8668749	3	52	nascimento1	nascimento1	PROPN
bjos-8668749	3	53	,	,	PUNCT
bjos-8668749	3	54	thays	thay	VERB
bjos-8668749	3	55	obando	obando	ADJ
bjos-8668749	3	56	brito1	brito1	ADV
bjos-8668749	3	57	,	,	PUNCT
bjos-8668749	3	58	andreza	andreza	PROPN
bjos-8668749	3	59	menezes	meneze	VERB
bjos-8668749	3	60	lima1	lima1	PROPN
bjos-8668749	3	61	,	,	PUNCT
bjos-8668749	3	62	carlos	carlos	PROPN
bjos-8668749	3	63	nelson	nelson	PROPN
bjos-8668749	3	64	elias1	elias1	PROPN
bjos-8668749	3	65	*	*	PUNCT
bjos-8668749	3	66	aim	aim	NOUN
bjos-8668749	3	67	:	:	PUNCT
bjos-8668749	3	68	this	this	DET
bjos-8668749	3	69	review	review	NOUN
bjos-8668749	3	70	aims	aim	VERB
bjos-8668749	3	71	to	to	PART
bjos-8668749	3	72	present	present	VERB
bjos-8668749	3	73	the	the	DET
bjos-8668749	3	74	mechanisms	mechanism	NOUN
bjos-8668749	3	75	of	of	ADP
bjos-8668749	3	76	protein	protein	NOUN
bjos-8668749	3	77	interactions	interaction	NOUN
bjos-8668749	3	78	with	with	ADP
bjos-8668749	3	79	titanium	titanium	NOUN
bjos-8668749	3	80	dental	dental	ADJ
bjos-8668749	3	81	implant	implant	ADJ
bjos-8668749	3	82	surfaces	surface	NOUN
bjos-8668749	3	83	.	.	PUNCT
bjos-8668749	4	1	methods	method	NOUN
bjos-8668749	4	2	:	:	PUNCT
bjos-8668749	4	3	the	the	DET
bjos-8668749	4	4	analyses	analysis	NOUN
bjos-8668749	4	5	were	be	AUX
bjos-8668749	4	6	based	base	VERB
bjos-8668749	4	7	on	on	ADP
bjos-8668749	4	8	searches	search	NOUN
bjos-8668749	4	9	of	of	ADP
bjos-8668749	4	10	scientific	scientific	ADJ
bjos-8668749	4	11	articles	article	NOUN
bjos-8668749	4	12	available	available	ADJ
bjos-8668749	4	13	in	in	ADP
bjos-8668749	4	14	english	english	PROPN
bjos-8668749	4	15	and	and	CCONJ
bjos-8668749	4	16	portuguese	portuguese	PROPN
bjos-8668749	4	17	in	in	ADP
bjos-8668749	4	18	pubmed	pubmed	PROPN
bjos-8668749	4	19	(	(	PUNCT
bjos-8668749	4	20	medline	medline	NOUN
bjos-8668749	4	21	)	)	PUNCT
bjos-8668749	4	22	,	,	PUNCT
bjos-8668749	4	23	bireme	bireme	NOUN
bjos-8668749	4	24	(	(	PUNCT
bjos-8668749	4	25	lilacs	lilacs	PROPN
bjos-8668749	4	26	)	)	PUNCT
bjos-8668749	4	27	,	,	PUNCT
bjos-8668749	4	28	scielo	scielo	NOUN
bjos-8668749	4	29	,	,	PUNCT
bjos-8668749	4	30	web	web	NOUN
bjos-8668749	4	31	of	of	ADP
bjos-8668749	4	32	science	science	NOUN
bjos-8668749	4	33	and	and	CCONJ
bjos-8668749	4	34	google	google	PROPN
bjos-8668749	4	35	scholar	scholar	NOUN
bjos-8668749	4	36	.	.	PUNCT
bjos-8668749	5	1	results	result	NOUN
bjos-8668749	5	2	:	:	PUNCT
bjos-8668749	5	3	titanium	titanium	NOUN
bjos-8668749	5	4	dental	dental	ADJ
bjos-8668749	5	5	implant	implant	ADJ
bjos-8668749	5	6	treatments	treatment	NOUN
bjos-8668749	5	7	success	success	NOUN
bjos-8668749	5	8	rates	rate	NOUN
bjos-8668749	5	9	(	(	PUNCT
bjos-8668749	5	10	95	95	NUM
bjos-8668749	5	11	-	-	SYM
bjos-8668749	5	12	98	98	NUM
bjos-8668749	5	13	%	%	NOUN
bjos-8668749	5	14	)	)	PUNCT
bjos-8668749	5	15	are	be	AUX
bjos-8668749	5	16	mainly	mainly	ADV
bjos-8668749	5	17	due	due	ADJ
bjos-8668749	5	18	to	to	ADP
bjos-8668749	5	19	the	the	DET
bjos-8668749	5	20	biocompatibility	biocompatibility	NOUN
bjos-8668749	5	21	of	of	ADP
bjos-8668749	5	22	titanium	titanium	NOUN
bjos-8668749	5	23	oxide	oxide	NOUN
bjos-8668749	5	24	on	on	ADP
bjos-8668749	5	25	the	the	DET
bjos-8668749	5	26	implant	implant	ADJ
bjos-8668749	5	27	surface	surface	NOUN
bjos-8668749	5	28	,	,	PUNCT
bjos-8668749	5	29	surgical	surgical	ADJ
bjos-8668749	5	30	techniques	technique	NOUN
bjos-8668749	5	31	adopted	adopt	VERB
bjos-8668749	5	32	,	,	PUNCT
bjos-8668749	5	33	good	good	ADJ
bjos-8668749	5	34	implants	implant	NOUN
bjos-8668749	5	35	manufacturing	manufacturing	NOUN
bjos-8668749	5	36	processes	process	NOUN
bjos-8668749	5	37	and	and	CCONJ
bjos-8668749	5	38	biomechanical	biomechanical	ADJ
bjos-8668749	5	39	knowledge	knowledge	NOUN
bjos-8668749	5	40	of	of	ADP
bjos-8668749	5	41	the	the	DET
bjos-8668749	5	42	systems	system	NOUN
bjos-8668749	5	43	.	.	PUNCT
bjos-8668749	6	1	studies	study	NOUN
bjos-8668749	6	2	in	in	ADP
bjos-8668749	6	3	past	past	ADJ
bjos-8668749	6	4	decades	decade	NOUN
bjos-8668749	6	5	has	have	AUX
bjos-8668749	6	6	empirically	empirically	ADV
bjos-8668749	6	7	developed	develop	VERB
bjos-8668749	6	8	implant	implant	ADJ
bjos-8668749	6	9	surfaces	surface	NOUN
bjos-8668749	6	10	with	with	ADP
bjos-8668749	6	11	significant	significant	ADJ
bjos-8668749	6	12	changes	change	NOUN
bjos-8668749	6	13	in	in	ADP
bjos-8668749	6	14	morphologies	morphology	NOUN
bjos-8668749	6	15	,	,	PUNCT
bjos-8668749	6	16	roughness	roughness	NOUN
bjos-8668749	6	17	,	,	PUNCT
bjos-8668749	6	18	wettability	wettability	NOUN
bjos-8668749	6	19	,	,	PUNCT
bjos-8668749	6	20	surface	surface	NOUN
bjos-8668749	6	21	energy	energy	NOUN
bjos-8668749	6	22	,	,	PUNCT
bjos-8668749	6	23	chemical	chemical	NOUN
bjos-8668749	6	24	composition	composition	NOUN
bjos-8668749	6	25	,	,	PUNCT
bjos-8668749	6	26	and	and	CCONJ
bjos-8668749	6	27	chemical	chemical	NOUN
bjos-8668749	6	28	groups	group	NOUN
bjos-8668749	6	29	density	density	NOUN
bjos-8668749	6	30	or	or	CCONJ
bjos-8668749	6	31	deposited	deposit	VERB
bjos-8668749	6	32	molecules	molecule	NOUN
bjos-8668749	6	33	.	.	PUNCT
bjos-8668749	7	1	these	these	DET
bjos-8668749	7	2	changes	change	NOUN
bjos-8668749	7	3	promoted	promote	VERB
bjos-8668749	7	4	better	well	ADJ
bjos-8668749	7	5	protein	protein	NOUN
bjos-8668749	7	6	adsorption	adsorption	NOUN
bjos-8668749	7	7	,	,	PUNCT
bjos-8668749	7	8	osteoblast	osteoblast	ADJ
bjos-8668749	7	9	adhesion	adhesion	NOUN
bjos-8668749	7	10	,	,	PUNCT
bjos-8668749	7	11	and	and	CCONJ
bjos-8668749	7	12	changes	change	NOUN
bjos-8668749	7	13	in	in	ADP
bjos-8668749	7	14	the	the	DET
bjos-8668749	7	15	mechanisms	mechanism	NOUN
bjos-8668749	7	16	involved	involve	VERB
bjos-8668749	7	17	in	in	ADP
bjos-8668749	7	18	osseointegration	osseointegration	NOUN
bjos-8668749	7	19	.	.	PUNCT
bjos-8668749	8	1	thus	thus	ADV
bjos-8668749	8	2	,	,	PUNCT
bjos-8668749	8	3	the	the	DET
bjos-8668749	8	4	time	time	NOUN
bjos-8668749	8	5	to	to	PART
bjos-8668749	8	6	put	put	VERB
bjos-8668749	8	7	the	the	DET
bjos-8668749	8	8	implant	implant	NOUN
bjos-8668749	8	9	in	in	ADP
bjos-8668749	8	10	function	function	NOUN
bjos-8668749	8	11	has	have	AUX
bjos-8668749	8	12	been	be	AUX
bjos-8668749	8	13	reduced	reduce	VERB
bjos-8668749	8	14	and	and	CCONJ
bjos-8668749	8	15	the	the	DET
bjos-8668749	8	16	success	success	NOUN
bjos-8668749	8	17	rates	rate	NOUN
bjos-8668749	8	18	have	have	AUX
bjos-8668749	8	19	increased	increase	VERB
bjos-8668749	8	20	.	.	PUNCT
bjos-8668749	9	1	in	in	ADP
bjos-8668749	9	2	the	the	DET
bjos-8668749	9	3	osseointegration	osseointegration	NOUN
bjos-8668749	9	4	process	process	NOUN
bjos-8668749	9	5	,	,	PUNCT
bjos-8668749	9	6	at	at	ADP
bjos-8668749	9	7	the	the	DET
bjos-8668749	9	8	nanoscale	nanoscale	NOUN
bjos-8668749	9	9	,	,	PUNCT
bjos-8668749	9	10	there	there	PRON
bjos-8668749	9	11	is	be	VERB
bjos-8668749	9	12	no	no	DET
bjos-8668749	9	13	contact	contact	NOUN
bjos-8668749	9	14	between	between	ADP
bjos-8668749	9	15	the	the	DET
bjos-8668749	9	16	bone	bone	NOUN
bjos-8668749	9	17	and	and	CCONJ
bjos-8668749	9	18	the	the	DET
bjos-8668749	9	19	implant	implant	ADJ
bjos-8668749	9	20	surface	surface	NOUN
bjos-8668749	9	21	,	,	PUNCT
bjos-8668749	9	22	but	but	CCONJ
bjos-8668749	9	23	there	there	PRON
bjos-8668749	9	24	is	be	VERB
bjos-8668749	9	25	the	the	DET
bjos-8668749	9	26	formation	formation	NOUN
bjos-8668749	9	27	of	of	ADP
bjos-8668749	9	28	a	a	DET
bjos-8668749	9	29	protein	protein	NOUN
bjos-8668749	9	30	anchorage	anchorage	NOUN
bjos-8668749	9	31	between	between	ADP
bjos-8668749	9	32	the	the	DET
bjos-8668749	9	33	periosteum	periosteum	NOUN
bjos-8668749	9	34	and	and	CCONJ
bjos-8668749	9	35	the	the	DET
bjos-8668749	9	36	implant	implant	NOUN
bjos-8668749	9	37	with	with	ADP
bjos-8668749	9	38	an	an	DET
bjos-8668749	9	39	interface	interface	NOUN
bjos-8668749	9	40	formed	form	VERB
bjos-8668749	9	41	by	by	ADP
bjos-8668749	9	42	proteins	protein	NOUN
bjos-8668749	9	43	.	.	PUNCT
bjos-8668749	10	1	in	in	ADP
bjos-8668749	10	2	all	all	DET
bjos-8668749	10	3	the	the	DET
bjos-8668749	10	4	reactions	reaction	NOUN
bjos-8668749	10	5	between	between	ADP
bjos-8668749	10	6	the	the	DET
bjos-8668749	10	7	body	body	NOUN
bjos-8668749	10	8	and	and	CCONJ
bjos-8668749	10	9	the	the	DET
bjos-8668749	10	10	implant	implant	ADJ
bjos-8668749	10	11	surface	surface	NOUN
bjos-8668749	10	12	,	,	PUNCT
bjos-8668749	10	13	the	the	DET
bjos-8668749	10	14	activities	activity	NOUN
bjos-8668749	10	15	of	of	ADP
bjos-8668749	10	16	fibronectin	fibronectin	NOUN
bjos-8668749	10	17	and	and	CCONJ
bjos-8668749	10	18	integrin	integrin	NOUN
bjos-8668749	10	19	are	be	AUX
bjos-8668749	10	20	essential	essential	ADJ
bjos-8668749	10	21	,	,	PUNCT
bjos-8668749	10	22	since	since	SCONJ
bjos-8668749	10	23	they	they	PRON
bjos-8668749	10	24	are	be	AUX
bjos-8668749	10	25	responsible	responsible	ADJ
bjos-8668749	10	26	for	for	ADP
bjos-8668749	10	27	transmitting	transmit	VERB
bjos-8668749	10	28	information	information	NOUN
bjos-8668749	10	29	to	to	ADP
bjos-8668749	10	30	the	the	DET
bjos-8668749	10	31	cell	cell	NOUN
bjos-8668749	10	32	for	for	ADP
bjos-8668749	10	33	its	its	PRON
bjos-8668749	10	34	differentiation	differentiation	NOUN
bjos-8668749	10	35	,	,	PUNCT
bjos-8668749	10	36	adhesion	adhesion	NOUN
bjos-8668749	10	37	and	and	CCONJ
bjos-8668749	10	38	mobility	mobility	NOUN
bjos-8668749	10	39	.	.	PUNCT
bjos-8668749	11	1	conclusion	conclusion	NOUN
bjos-8668749	11	2	:	:	PUNCT
bjos-8668749	11	3	thus	thus	ADV
bjos-8668749	11	4	,	,	PUNCT
bjos-8668749	11	5	the	the	DET
bjos-8668749	11	6	analyses	analysis	NOUN
bjos-8668749	11	7	of	of	ADP
bjos-8668749	11	8	protein	protein	NOUN
bjos-8668749	11	9	-	-	PUNCT
bjos-8668749	11	10	implant	implant	ADJ
bjos-8668749	11	11	interactions	interaction	NOUN
bjos-8668749	11	12	are	be	AUX
bjos-8668749	11	13	indispensable	indispensable	ADJ
bjos-8668749	11	14	for	for	ADP
bjos-8668749	11	15	a	a	DET
bjos-8668749	11	16	better	well	ADJ
bjos-8668749	11	17	understanding	understanding	NOUN
bjos-8668749	11	18	of	of	ADP
bjos-8668749	11	19	the	the	DET
bjos-8668749	11	20	performance	performance	NOUN
bjos-8668749	11	21	of	of	ADP
bjos-8668749	11	22	osseointegrated	osseointegrate	VERB
bjos-8668749	11	23	dental	dental	ADJ
bjos-8668749	11	24	implants	implant	NOUN
bjos-8668749	11	25	.	.	PUNCT
bjos-8668749	12	1	keywords	keyword	NOUN
bjos-8668749	12	2	:	:	PUNCT
bjos-8668749	12	3	osseointegration	osseointegration	NOUN
bjos-8668749	12	4	.	.	PUNCT
bjos-8668749	13	1	bone	bone	NOUN
bjos-8668749	13	2	-	-	PUNCT
bjos-8668749	13	3	implant	implant	ADJ
bjos-8668749	13	4	inteface	inteface	NOUN
bjos-8668749	13	5	.	.	PUNCT
bjos-8668749	14	1	dental	dental	ADJ
bjos-8668749	14	2	implants	implant	NOUN
bjos-8668749	14	3	.	.	PUNCT
bjos-8668749	15	1	proteins	protein	NOUN
bjos-8668749	15	2	.	.	PUNCT
bjos-8668749	16	1	https://orcid.org/0000-0001-8010-7382	https://orcid.org/0000-0001-8010-7382	NOUN
bjos-8668749	16	2	https://orcid.org/0000-0001-9833-4778	https://orcid.org/0000-0001-9833-4778	PROPN
bjos-8668749	16	3	https://orcid.org/0000-0002-5086-6051	https://orcid.org/0000-0002-5086-6051	PROPN
bjos-8668749	16	4	https://orcid.org/0000-0002-7560-6926	https://orcid.org/0000-0002-7560-6926	NOUN
bjos-8668749	16	5	2	2	NUM
bjos-8668749	16	6	nascimento	nascimento	PROPN
bjos-8668749	16	7	et	et	PROPN
bjos-8668749	16	8	al	al	PROPN
bjos-8668749	16	9	.	.	PROPN
bjos-8668749	17	1	braz	braz	PROPN
bjos-8668749	17	2	j	j	PROPN
bjos-8668749	17	3	oral	oral	PROPN
bjos-8668749	17	4	sci	sci	PROPN
bjos-8668749	17	5	.	.	PUNCT
bjos-8668749	18	1	2023;22	2023;22	NUM
bjos-8668749	18	2	:	:	PUNCT
bjos-8668749	18	3	e238749	e238749	PROPN
bjos-8668749	18	4	introduction	introduction	NOUN
bjos-8668749	18	5	in	in	ADP
bjos-8668749	18	6	the	the	DET
bjos-8668749	18	7	past	past	NOUN
bjos-8668749	18	8	,	,	PUNCT
bjos-8668749	18	9	materials	material	NOUN
bjos-8668749	18	10	used	use	VERB
bjos-8668749	18	11	as	as	ADP
bjos-8668749	18	12	biomaterials	biomaterial	NOUN
bjos-8668749	18	13	were	be	AUX
bjos-8668749	18	14	selected	select	VERB
bjos-8668749	18	15	based	base	VERB
bjos-8668749	18	16	on	on	ADP
bjos-8668749	18	17	their	their	PRON
bjos-8668749	18	18	performance	performance	NOUN
bjos-8668749	18	19	in	in	ADP
bjos-8668749	18	20	other	other	ADJ
bjos-8668749	18	21	than	than	ADP
bjos-8668749	18	22	medical	medical	ADJ
bjos-8668749	18	23	-	-	PUNCT
bjos-8668749	18	24	dental	dental	ADJ
bjos-8668749	18	25	applications1	applications1	NOUN
bjos-8668749	18	26	.	.	PUNCT
bjos-8668749	19	1	the	the	DET
bjos-8668749	19	2	material	material	NOUN
bjos-8668749	19	3	selection	selection	NOUN
bjos-8668749	19	4	for	for	ADP
bjos-8668749	19	5	dental	dental	ADJ
bjos-8668749	19	6	implants	implant	NOUN
bjos-8668749	19	7	was	be	AUX
bjos-8668749	19	8	made	make	VERB
bjos-8668749	19	9	considering	consider	VERB
bjos-8668749	19	10	mainly	mainly	ADV
bjos-8668749	19	11	mechanical	mechanical	ADJ
bjos-8668749	19	12	and	and	CCONJ
bjos-8668749	19	13	corrosion	corrosion	NOUN
bjos-8668749	19	14	resistance	resistance	NOUN
bjos-8668749	19	15	(	(	PUNCT
bjos-8668749	19	16	first	first	ADJ
bjos-8668749	19	17	generation	generation	NOUN
bjos-8668749	19	18	biomaterials	biomaterial	NOUN
bjos-8668749	19	19	)	)	PUNCT
bjos-8668749	19	20	.	.	PUNCT
bjos-8668749	20	1	no	no	DET
bjos-8668749	20	2	consideration	consideration	NOUN
bjos-8668749	20	3	was	be	AUX
bjos-8668749	20	4	given	give	VERB
bjos-8668749	20	5	to	to	ADP
bjos-8668749	20	6	the	the	DET
bjos-8668749	20	7	immune	immune	ADJ
bjos-8668749	20	8	response	response	NOUN
bjos-8668749	20	9	or	or	CCONJ
bjos-8668749	20	10	hypersensitivity	hypersensitivity	NOUN
bjos-8668749	20	11	reactions	reaction	NOUN
bjos-8668749	20	12	that	that	PRON
bjos-8668749	20	13	could	could	AUX
bjos-8668749	20	14	occur	occur	VERB
bjos-8668749	20	15	a	a	DET
bjos-8668749	20	16	few	few	ADJ
bjos-8668749	20	17	years	year	NOUN
bjos-8668749	20	18	after	after	ADP
bjos-8668749	20	19	implantation	implantation	NOUN
bjos-8668749	20	20	due	due	ADP
bjos-8668749	20	21	to	to	ADP
bjos-8668749	20	22	ion	ion	NOUN
bjos-8668749	20	23	release	release	NOUN
bjos-8668749	20	24	and	and	CCONJ
bjos-8668749	20	25	the	the	DET
bjos-8668749	20	26	proteins	protein	NOUN
bjos-8668749	20	27	interactions	interaction	NOUN
bjos-8668749	20	28	with	with	ADP
bjos-8668749	20	29	the	the	DET
bjos-8668749	20	30	implant	implant	ADJ
bjos-8668749	20	31	surfaces2	surfaces2	NOUN
bjos-8668749	20	32	.	.	PUNCT
bjos-8668749	21	1	in	in	ADP
bjos-8668749	21	2	many	many	ADJ
bjos-8668749	21	3	applications	application	NOUN
bjos-8668749	21	4	the	the	DET
bjos-8668749	21	5	implantations	implantation	NOUN
bjos-8668749	21	6	’	'	PUNCT
bjos-8668749	21	7	results	result	NOUN
bjos-8668749	21	8	were	be	AUX
bjos-8668749	21	9	disastrous	disastrous	ADJ
bjos-8668749	21	10	and	and	CCONJ
bjos-8668749	21	11	even	even	ADV
bjos-8668749	21	12	led	lead	VERB
bjos-8668749	21	13	to	to	ADP
bjos-8668749	21	14	irreversible	irreversible	ADJ
bjos-8668749	21	15	damage	damage	NOUN
bjos-8668749	21	16	of	of	ADP
bjos-8668749	21	17	the	the	DET
bjos-8668749	21	18	patient	patient	NOUN
bjos-8668749	21	19	’s	’s	PART
bjos-8668749	21	20	organs	organ	NOUN
bjos-8668749	21	21	with	with	ADP
bjos-8668749	21	22	the	the	DET
bjos-8668749	21	23	need	need	NOUN
bjos-8668749	21	24	for	for	ADP
bjos-8668749	21	25	amputation3	amputation3	PROPN
bjos-8668749	21	26	.	.	PUNCT
bjos-8668749	22	1	the	the	DET
bjos-8668749	22	2	knowledge	knowledge	NOUN
bjos-8668749	22	3	about	about	ADP
bjos-8668749	22	4	the	the	DET
bjos-8668749	22	5	interactions	interaction	NOUN
bjos-8668749	22	6	between	between	ADP
bjos-8668749	22	7	organisms	organism	NOUN
bjos-8668749	22	8	and	and	CCONJ
bjos-8668749	22	9	biomaterials	biomaterial	NOUN
bjos-8668749	22	10	developed	develop	VERB
bjos-8668749	22	11	,	,	PUNCT
bjos-8668749	22	12	paradigms	paradigm	NOUN
bjos-8668749	22	13	were	be	AUX
bjos-8668749	22	14	changed	change	VERB
bjos-8668749	22	15	and	and	CCONJ
bjos-8668749	22	16	the	the	DET
bjos-8668749	22	17	molecular	molecular	ADJ
bjos-8668749	22	18	and	and	CCONJ
bjos-8668749	22	19	biomechanical	biomechanical	ADJ
bjos-8668749	22	20	aspects	aspect	NOUN
bjos-8668749	22	21	associated	associate	VERB
bjos-8668749	22	22	with	with	ADP
bjos-8668749	22	23	the	the	DET
bjos-8668749	22	24	cells	cell	NOUN
bjos-8668749	22	25	interactions	interaction	NOUN
bjos-8668749	22	26	with	with	ADP
bjos-8668749	22	27	surfaces	surface	NOUN
bjos-8668749	22	28	began	begin	VERB
bjos-8668749	22	29	to	to	PART
bjos-8668749	22	30	be	be	AUX
bjos-8668749	22	31	considered	consider	VERB
bjos-8668749	22	32	(	(	PUNCT
bjos-8668749	22	33	second	second	ADJ
bjos-8668749	22	34	generation	generation	NOUN
bjos-8668749	22	35	biomaterials	biomaterial	NOUN
bjos-8668749	22	36	)	)	PUNCT
bjos-8668749	22	37	.	.	PUNCT
bjos-8668749	23	1	biomaterials	biomaterial	NOUN
bjos-8668749	23	2	are	be	AUX
bjos-8668749	23	3	no	no	ADV
bjos-8668749	23	4	longer	long	ADV
bjos-8668749	23	5	just	just	ADV
bjos-8668749	23	6	organs	organ	NOUN
bjos-8668749	23	7	or	or	CCONJ
bjos-8668749	23	8	functions	function	NOUN
bjos-8668749	23	9	replacements	replacement	NOUN
bjos-8668749	23	10	,	,	PUNCT
bjos-8668749	23	11	but	but	CCONJ
bjos-8668749	23	12	devices	device	NOUN
bjos-8668749	23	13	that	that	PRON
bjos-8668749	23	14	interact	interact	VERB
bjos-8668749	23	15	with	with	ADP
bjos-8668749	23	16	cells4	cells4	PROPN
bjos-8668749	23	17	.	.	PUNCT
bjos-8668749	24	1	the	the	DET
bjos-8668749	24	2	new	new	ADJ
bjos-8668749	24	3	biomaterials	biomaterial	NOUN
bjos-8668749	24	4	allow	allow	VERB
bjos-8668749	24	5	adhesion	adhesion	NOUN
bjos-8668749	24	6	of	of	ADP
bjos-8668749	24	7	specific	specific	ADJ
bjos-8668749	24	8	proteins	protein	NOUN
bjos-8668749	24	9	in	in	ADP
bjos-8668749	24	10	order	order	NOUN
bjos-8668749	24	11	to	to	PART
bjos-8668749	24	12	stimulate	stimulate	VERB
bjos-8668749	24	13	cell	cell	NOUN
bjos-8668749	24	14	differentiation	differentiation	NOUN
bjos-8668749	24	15	to	to	PART
bjos-8668749	24	16	obtain	obtain	VERB
bjos-8668749	24	17	the	the	DET
bjos-8668749	24	18	expected	expect	VERB
bjos-8668749	24	19	physiological	physiological	ADJ
bjos-8668749	24	20	response5	response5	NOUN
bjos-8668749	24	21	.	.	PUNCT
bjos-8668749	25	1	in	in	ADP
bjos-8668749	25	2	some	some	DET
bjos-8668749	25	3	situations	situation	NOUN
bjos-8668749	25	4	,	,	PUNCT
bjos-8668749	25	5	adhesion	adhesion	NOUN
bjos-8668749	25	6	of	of	ADP
bjos-8668749	25	7	cells	cell	NOUN
bjos-8668749	25	8	or	or	CCONJ
bjos-8668749	25	9	proteins	protein	NOUN
bjos-8668749	25	10	to	to	ADP
bjos-8668749	25	11	the	the	DET
bjos-8668749	25	12	biomaterial	biomaterial	NOUN
bjos-8668749	25	13	is	be	AUX
bjos-8668749	25	14	not	not	PART
bjos-8668749	25	15	desired	desire	VERB
bjos-8668749	25	16	,	,	PUNCT
bjos-8668749	25	17	as	as	ADP
bjos-8668749	25	18	in	in	ADP
bjos-8668749	25	19	the	the	DET
bjos-8668749	25	20	case	case	NOUN
bjos-8668749	25	21	of	of	ADP
bjos-8668749	25	22	coronary	coronary	ADJ
bjos-8668749	25	23	stents	stent	NOUN
bjos-8668749	25	24	.	.	PUNCT
bjos-8668749	26	1	in	in	ADP
bjos-8668749	26	2	others	other	NOUN
bjos-8668749	26	3	,	,	PUNCT
bjos-8668749	26	4	implants	implant	NOUN
bjos-8668749	26	5	are	be	AUX
bjos-8668749	26	6	encapsulated	encapsulate	VERB
bjos-8668749	26	7	by	by	ADP
bjos-8668749	26	8	fibrous	fibrous	ADJ
bjos-8668749	26	9	tissues	tissue	NOUN
bjos-8668749	26	10	,	,	PUNCT
bjos-8668749	26	11	orthopedic	orthopedic	ADJ
bjos-8668749	26	12	devices3	devices3	PROPN
bjos-8668749	26	13	.	.	PUNCT
bjos-8668749	27	1	the	the	DET
bjos-8668749	27	2	trend	trend	NOUN
bjos-8668749	27	3	is	be	AUX
bjos-8668749	27	4	to	to	PART
bjos-8668749	27	5	select	select	VERB
bjos-8668749	27	6	the	the	DET
bjos-8668749	27	7	biomaterial	biomaterial	NOUN
bjos-8668749	27	8	for	for	ADP
bjos-8668749	27	9	individualized	individualized	ADJ
bjos-8668749	27	10	and	and	CCONJ
bjos-8668749	27	11	personalized	personalized	ADJ
bjos-8668749	27	12	application	application	NOUN
bjos-8668749	27	13	,	,	PUNCT
bjos-8668749	27	14	which	which	PRON
bjos-8668749	27	15	may	may	AUX
bjos-8668749	27	16	be	be	AUX
bjos-8668749	27	17	suitable	suitable	ADJ
bjos-8668749	27	18	for	for	ADP
bjos-8668749	27	19	one	one	NUM
bjos-8668749	27	20	recipient	recipient	NOUN
bjos-8668749	27	21	organism	organism	NOUN
bjos-8668749	27	22	and	and	CCONJ
bjos-8668749	27	23	inappropriate	inappropriate	ADJ
bjos-8668749	27	24	for	for	ADP
bjos-8668749	27	25	another6	another6	PROPN
bjos-8668749	27	26	.	.	PUNCT
bjos-8668749	28	1	thus	thus	ADV
bjos-8668749	28	2	,	,	PUNCT
bjos-8668749	28	3	to	to	PART
bjos-8668749	28	4	reach	reach	VERB
bjos-8668749	28	5	this	this	DET
bjos-8668749	28	6	level	level	NOUN
bjos-8668749	28	7	,	,	PUNCT
bjos-8668749	28	8	researchers	researcher	NOUN
bjos-8668749	28	9	need	need	VERB
bjos-8668749	28	10	to	to	PART
bjos-8668749	28	11	know	know	VERB
bjos-8668749	28	12	the	the	DET
bjos-8668749	28	13	interactions	interaction	NOUN
bjos-8668749	28	14	of	of	ADP
bjos-8668749	28	15	the	the	DET
bjos-8668749	28	16	biomaterial	biomaterial	NOUN
bjos-8668749	28	17	with	with	ADP
bjos-8668749	28	18	the	the	DET
bjos-8668749	28	19	body	body	NOUN
bjos-8668749	28	20	.	.	PUNCT
bjos-8668749	29	1	there	there	PRON
bjos-8668749	29	2	is	be	VERB
bjos-8668749	29	3	a	a	DET
bjos-8668749	29	4	need	need	NOUN
bjos-8668749	29	5	to	to	PART
bjos-8668749	29	6	understand	understand	VERB
bjos-8668749	29	7	how	how	SCONJ
bjos-8668749	29	8	the	the	DET
bjos-8668749	29	9	mechanical	mechanical	ADJ
bjos-8668749	29	10	or	or	CCONJ
bjos-8668749	29	11	biochemical	biochemical	ADJ
bjos-8668749	29	12	bonding	bonding	NOUN
bjos-8668749	29	13	of	of	ADP
bjos-8668749	29	14	the	the	DET
bjos-8668749	29	15	implant	implant	NOUN
bjos-8668749	29	16	to	to	ADP
bjos-8668749	29	17	the	the	DET
bjos-8668749	29	18	tissues	tissue	NOUN
bjos-8668749	29	19	occurs	occur	VERB
bjos-8668749	29	20	.	.	PUNCT
bjos-8668749	30	1	current	current	ADJ
bjos-8668749	30	2	data	datum	NOUN
bjos-8668749	30	3	show	show	VERB
bjos-8668749	30	4	that	that	SCONJ
bjos-8668749	30	5	the	the	DET
bjos-8668749	30	6	bonding	bonding	NOUN
bjos-8668749	30	7	of	of	ADP
bjos-8668749	30	8	osseointegrable	osseointegrable	ADJ
bjos-8668749	30	9	dental	dental	ADJ
bjos-8668749	30	10	implants	implant	NOUN
bjos-8668749	30	11	to	to	ADP
bjos-8668749	30	12	bone	bone	NOUN
bjos-8668749	30	13	occurs	occur	VERB
bjos-8668749	30	14	through	through	ADP
bjos-8668749	30	15	layers	layer	NOUN
bjos-8668749	30	16	of	of	ADP
bjos-8668749	30	17	proteins	protein	NOUN
bjos-8668749	30	18	and	and	CCONJ
bjos-8668749	30	19	glycoproteins	glycoprotein	NOUN
bjos-8668749	30	20	forming	form	VERB
bjos-8668749	30	21	a	a	DET
bjos-8668749	30	22	bone	bone	NOUN
bjos-8668749	30	23	-	-	PUNCT
bjos-8668749	30	24	implant	implant	ADJ
bjos-8668749	30	25	interface7	interface7	PROPN
bjos-8668749	30	26	.	.	PUNCT
bjos-8668749	31	1	however	however	ADV
bjos-8668749	31	2	,	,	PUNCT
bjos-8668749	31	3	knowledge	knowledge	NOUN
bjos-8668749	31	4	about	about	ADP
bjos-8668749	31	5	the	the	DET
bjos-8668749	31	6	regulatory	regulatory	ADJ
bjos-8668749	31	7	mechanisms	mechanism	NOUN
bjos-8668749	31	8	,	,	PUNCT
bjos-8668749	31	9	or	or	CCONJ
bjos-8668749	31	10	formation	formation	NOUN
bjos-8668749	31	11	,	,	PUNCT
bjos-8668749	31	12	of	of	ADP
bjos-8668749	31	13	this	this	DET
bjos-8668749	31	14	bone	bone	NOUN
bjos-8668749	31	15	-	-	PUNCT
bjos-8668749	31	16	implant	implant	ADJ
bjos-8668749	31	17	interface	interface	NOUN
bjos-8668749	31	18	is	be	AUX
bjos-8668749	31	19	still	still	ADV
bjos-8668749	31	20	incomplete8	incomplete8	PROPN
bjos-8668749	31	21	.	.	PUNCT
bjos-8668749	31	22	information	information	NOUN
bjos-8668749	31	23	related	relate	VERB
bjos-8668749	31	24	to	to	ADP
bjos-8668749	31	25	this	this	DET
bjos-8668749	31	26	topic	topic	NOUN
bjos-8668749	31	27	is	be	AUX
bjos-8668749	31	28	scattered	scatter	VERB
bjos-8668749	31	29	and	and	CCONJ
bjos-8668749	31	30	often	often	ADV
bjos-8668749	31	31	researchers	researcher	NOUN
bjos-8668749	31	32	from	from	ADP
bjos-8668749	31	33	complementary	complementary	ADJ
bjos-8668749	31	34	fields	field	NOUN
bjos-8668749	31	35	do	do	AUX
bjos-8668749	31	36	not	not	PART
bjos-8668749	31	37	exchange	exchange	VERB
bjos-8668749	31	38	information	information	NOUN
bjos-8668749	31	39	.	.	PUNCT
bjos-8668749	32	1	the	the	DET
bjos-8668749	32	2	hypothesis	hypothesis	NOUN
bjos-8668749	32	3	is	be	AUX
bjos-8668749	32	4	that	that	SCONJ
bjos-8668749	32	5	there	there	PRON
bjos-8668749	32	6	is	be	VERB
bjos-8668749	32	7	probably	probably	ADV
bjos-8668749	32	8	an	an	DET
bjos-8668749	32	9	interaction	interaction	NOUN
bjos-8668749	32	10	between	between	ADP
bjos-8668749	32	11	cell	cell	NOUN
bjos-8668749	32	12	membrane	membrane	NOUN
bjos-8668749	32	13	proteins	protein	NOUN
bjos-8668749	32	14	(	(	PUNCT
bjos-8668749	32	15	integrins	integrin	NOUN
bjos-8668749	32	16	)	)	PUNCT
bjos-8668749	32	17	with	with	ADP
bjos-8668749	32	18	the	the	DET
bjos-8668749	32	19	titanium	titanium	NOUN
bjos-8668749	32	20	oxide	oxide	NOUN
bjos-8668749	32	21	layer	layer	NOUN
bjos-8668749	32	22	mediated	mediate	VERB
bjos-8668749	32	23	by	by	ADP
bjos-8668749	32	24	other	other	ADJ
bjos-8668749	32	25	proteins	protein	NOUN
bjos-8668749	32	26	(	(	PUNCT
bjos-8668749	32	27	fibronectin	fibronectin	NOUN
bjos-8668749	32	28	)	)	PUNCT
bjos-8668749	32	29	.	.	PUNCT
bjos-8668749	33	1	given	give	VERB
bjos-8668749	33	2	this	this	DET
bjos-8668749	33	3	deficiency	deficiency	NOUN
bjos-8668749	33	4	,	,	PUNCT
bjos-8668749	33	5	the	the	DET
bjos-8668749	33	6	aim	aim	NOUN
bjos-8668749	33	7	of	of	ADP
bjos-8668749	33	8	this	this	DET
bjos-8668749	33	9	review	review	NOUN
bjos-8668749	33	10	is	be	AUX
bjos-8668749	33	11	to	to	PART
bjos-8668749	33	12	present	present	VERB
bjos-8668749	33	13	the	the	DET
bjos-8668749	33	14	mechanisms	mechanism	NOUN
bjos-8668749	33	15	of	of	ADP
bjos-8668749	33	16	protein	protein	NOUN
bjos-8668749	33	17	interactions	interaction	NOUN
bjos-8668749	33	18	with	with	ADP
bjos-8668749	33	19	titanium	titanium	NOUN
bjos-8668749	33	20	dental	dental	ADJ
bjos-8668749	33	21	implant	implant	ADJ
bjos-8668749	33	22	surfaces	surface	NOUN
bjos-8668749	33	23	.	.	PUNCT
bjos-8668749	34	1	methodology	methodology	NOUN
bjos-8668749	34	2	this	this	DET
bjos-8668749	34	3	study	study	NOUN
bjos-8668749	34	4	is	be	AUX
bjos-8668749	34	5	a	a	DET
bjos-8668749	34	6	literature	literature	NOUN
bjos-8668749	34	7	review	review	NOUN
bjos-8668749	34	8	that	that	PRON
bjos-8668749	34	9	aims	aim	VERB
bjos-8668749	34	10	to	to	PART
bjos-8668749	34	11	present	present	VERB
bjos-8668749	34	12	the	the	DET
bjos-8668749	34	13	interactions	interaction	NOUN
bjos-8668749	34	14	of	of	ADP
bjos-8668749	34	15	proteins	protein	NOUN
bjos-8668749	34	16	with	with	ADP
bjos-8668749	34	17	the	the	DET
bjos-8668749	34	18	surface	surface	NOUN
bjos-8668749	34	19	of	of	ADP
bjos-8668749	34	20	titanium	titanium	NOUN
bjos-8668749	34	21	osseointegrable	osseointegrable	ADJ
bjos-8668749	34	22	dental	dental	ADJ
bjos-8668749	34	23	implants	implant	NOUN
bjos-8668749	34	24	.	.	PUNCT
bjos-8668749	35	1	articles	article	NOUN
bjos-8668749	35	2	published	publish	VERB
bjos-8668749	35	3	in	in	ADP
bjos-8668749	35	4	portuguese	portuguese	PROPN
bjos-8668749	35	5	and	and	CCONJ
bjos-8668749	35	6	english	english	PROPN
bjos-8668749	35	7	during	during	ADP
bjos-8668749	35	8	the	the	DET
bjos-8668749	35	9	last	last	ADJ
bjos-8668749	35	10	fifteen	fifteen	NUM
bjos-8668749	35	11	years	year	NOUN
bjos-8668749	35	12	were	be	AUX
bjos-8668749	35	13	searched	search	VERB
bjos-8668749	35	14	.	.	PUNCT
bjos-8668749	36	1	the	the	DET
bjos-8668749	36	2	following	follow	VERB
bjos-8668749	36	3	databases	database	NOUN
bjos-8668749	36	4	were	be	AUX
bjos-8668749	36	5	used	use	VERB
bjos-8668749	36	6	as	as	ADP
bjos-8668749	36	7	search	search	NOUN
bjos-8668749	36	8	tools	tool	NOUN
bjos-8668749	36	9	:	:	PUNCT
bjos-8668749	36	10	pubmed	pubmed	PROPN
bjos-8668749	36	11	(	(	PUNCT
bjos-8668749	36	12	medline	medline	NOUN
bjos-8668749	36	13	)	)	PUNCT
bjos-8668749	36	14	,	,	PUNCT
bjos-8668749	36	15	bireme	bireme	NOUN
bjos-8668749	36	16	(	(	PUNCT
bjos-8668749	36	17	lilacs	lilacs	PROPN
bjos-8668749	36	18	)	)	PUNCT
bjos-8668749	36	19	,	,	PUNCT
bjos-8668749	36	20	scielo	scielo	NOUN
bjos-8668749	36	21	,	,	PUNCT
bjos-8668749	36	22	web	web	NOUN
bjos-8668749	36	23	of	of	ADP
bjos-8668749	36	24	science	science	NOUN
bjos-8668749	36	25	and	and	CCONJ
bjos-8668749	36	26	google	google	PROPN
bjos-8668749	36	27	academic	academic	NOUN
bjos-8668749	36	28	.	.	PUNCT
bjos-8668749	37	1	the	the	DET
bjos-8668749	37	2	keywords	keyword	NOUN
bjos-8668749	37	3	were	be	AUX
bjos-8668749	37	4	:	:	PUNCT
bjos-8668749	37	5	“	"	PUNCT
bjos-8668749	37	6	biomaterials	biomaterial	NOUN
bjos-8668749	37	7	”	"	PUNCT
bjos-8668749	37	8	,	,	PUNCT
bjos-8668749	37	9	“	"	PUNCT
bjos-8668749	37	10	dental	dental	ADJ
bjos-8668749	37	11	implants	implant	NOUN
bjos-8668749	37	12	”	"	PUNCT
bjos-8668749	37	13	,	,	PUNCT
bjos-8668749	37	14	“	"	PUNCT
bjos-8668749	37	15	dental	dental	ADJ
bjos-8668749	37	16	implant	implant	ADJ
bjos-8668749	37	17	surfaces	surface	NOUN
bjos-8668749	37	18	”	"	PUNCT
bjos-8668749	37	19	,	,	PUNCT
bjos-8668749	37	20	“	"	PUNCT
bjos-8668749	37	21	osseointegrable	osseointegrable	ADJ
bjos-8668749	37	22	implants	implant	NOUN
bjos-8668749	37	23	”	"	PUNCT
bjos-8668749	37	24	,	,	PUNCT
bjos-8668749	37	25	“	"	PUNCT
bjos-8668749	37	26	bone	bone	NOUN
bjos-8668749	37	27	matrix	matrix	NOUN
bjos-8668749	37	28	”	"	PUNCT
bjos-8668749	37	29	,	,	PUNCT
bjos-8668749	37	30	“	"	PUNCT
bjos-8668749	37	31	bone	bone	NOUN
bjos-8668749	37	32	proteins	protein	NOUN
bjos-8668749	37	33	”	"	PUNCT
bjos-8668749	37	34	,	,	PUNCT
bjos-8668749	37	35	“	"	PUNCT
bjos-8668749	37	36	osteogenesis	osteogenesis	NOUN
bjos-8668749	37	37	”	"	PUNCT
bjos-8668749	37	38	,	,	PUNCT
bjos-8668749	37	39	“	"	PUNCT
bjos-8668749	37	40	osseointegration	osseointegration	NOUN
bjos-8668749	37	41	”	"	PUNCT
bjos-8668749	37	42	,	,	PUNCT
bjos-8668749	37	43	“	"	PUNCT
bjos-8668749	37	44	osseointegration	osseointegration	NOUN
bjos-8668749	37	45	and	and	CCONJ
bjos-8668749	37	46	dental	dental	ADJ
bjos-8668749	37	47	implants	implant	NOUN
bjos-8668749	37	48	”	"	PUNCT
bjos-8668749	37	49	,	,	PUNCT
bjos-8668749	37	50	“	"	PUNCT
bjos-8668749	37	51	integrin	integrin	NOUN
bjos-8668749	37	52	”	"	PUNCT
bjos-8668749	37	53	,	,	PUNCT
bjos-8668749	37	54	“	"	PUNCT
bjos-8668749	37	55	integrin	integrin	NOUN
bjos-8668749	37	56	and	and	CCONJ
bjos-8668749	37	57	osseointegration	osseointegration	NOUN
bjos-8668749	37	58	”	"	PUNCT
bjos-8668749	37	59	,	,	PUNCT
bjos-8668749	37	60	“	"	PUNCT
bjos-8668749	37	61	fibronectin	fibronectin	NOUN
bjos-8668749	37	62	”	"	PUNCT
bjos-8668749	37	63	,	,	PUNCT
bjos-8668749	37	64	“	"	PUNCT
bjos-8668749	37	65	fibronectin	fibronectin	NOUN
bjos-8668749	37	66	and	and	CCONJ
bjos-8668749	37	67	osseointegration	osseointegration	NOUN
bjos-8668749	37	68	”	"	PUNCT
bjos-8668749	37	69	.	.	PUNCT
bjos-8668749	38	1	manual	manual	NOUN
bjos-8668749	39	1	3	3	NUM
bjos-8668749	39	2	nascimento	nascimento	PROPN
bjos-8668749	39	3	et	et	PROPN
bjos-8668749	39	4	al	al	PROPN
bjos-8668749	39	5	.	.	PROPN
bjos-8668749	39	6	braz	braz	PROPN
bjos-8668749	39	7	j	j	PROPN
bjos-8668749	39	8	oral	oral	PROPN
bjos-8668749	39	9	sci	sci	PROPN
bjos-8668749	39	10	.	.	PUNCT
bjos-8668749	40	1	2023;22	2023;22	NUM
bjos-8668749	40	2	:	:	PUNCT
bjos-8668749	40	3	e238749	e238749	PROPN
bjos-8668749	40	4	searches	search	NOUN
bjos-8668749	40	5	were	be	AUX
bjos-8668749	40	6	also	also	ADV
bjos-8668749	40	7	performed	perform	VERB
bjos-8668749	40	8	in	in	ADP
bjos-8668749	40	9	the	the	DET
bjos-8668749	40	10	references	reference	NOUN
bjos-8668749	40	11	of	of	ADP
bjos-8668749	40	12	the	the	DET
bjos-8668749	40	13	researched	research	VERB
bjos-8668749	40	14	articles	article	NOUN
bjos-8668749	40	15	and	and	CCONJ
bjos-8668749	40	16	books	book	NOUN
bjos-8668749	40	17	.	.	PUNCT
bjos-8668749	41	1	the	the	DET
bjos-8668749	41	2	main	main	ADJ
bjos-8668749	41	3	inclusion	inclusion	NOUN
bjos-8668749	41	4	criterion	criterion	NOUN
bjos-8668749	41	5	for	for	ADP
bjos-8668749	41	6	the	the	DET
bjos-8668749	41	7	articles	article	NOUN
bjos-8668749	41	8	was	be	AUX
bjos-8668749	41	9	that	that	SCONJ
bjos-8668749	41	10	they	they	PRON
bjos-8668749	41	11	addressed	address	VERB
bjos-8668749	41	12	the	the	DET
bjos-8668749	41	13	interaction	interaction	NOUN
bjos-8668749	41	14	process	process	NOUN
bjos-8668749	41	15	between	between	ADP
bjos-8668749	41	16	proteins	protein	NOUN
bjos-8668749	41	17	and	and	CCONJ
bjos-8668749	41	18	biomaterials	biomaterial	NOUN
bjos-8668749	41	19	.	.	PUNCT
bjos-8668749	42	1	results	result	VERB
bjos-8668749	42	2	biological	biological	ADJ
bjos-8668749	42	3	response	response	NOUN
bjos-8668749	42	4	and	and	CCONJ
bjos-8668749	42	5	osseointegrated	osseointegrate	VERB
bjos-8668749	42	6	implant	implant	ADJ
bjos-8668749	42	7	integration	integration	NOUN
bjos-8668749	42	8	brånemark	brånemark	NOUN
bjos-8668749	42	9	’s	’s	PART
bjos-8668749	42	10	osseointegration	osseointegration	NOUN
bjos-8668749	42	11	concept	concept	NOUN
bjos-8668749	42	12	appeared	appear	VERB
bjos-8668749	42	13	in	in	ADP
bjos-8668749	42	14	1960	1960	NUM
bjos-8668749	42	15	with	with	ADP
bjos-8668749	42	16	the	the	DET
bjos-8668749	42	17	perspective	perspective	NOUN
bjos-8668749	42	18	that	that	SCONJ
bjos-8668749	42	19	the	the	DET
bjos-8668749	42	20	bone	bone	NOUN
bjos-8668749	42	21	maintained	maintain	VERB
bjos-8668749	42	22	full	full	ADJ
bjos-8668749	42	23	contact	contact	NOUN
bjos-8668749	42	24	with	with	ADP
bjos-8668749	42	25	the	the	DET
bjos-8668749	42	26	implant	implant	NOUN
bjos-8668749	42	27	,	,	PUNCT
bjos-8668749	42	28	so	so	SCONJ
bjos-8668749	42	29	that	that	SCONJ
bjos-8668749	42	30	it	it	PRON
bjos-8668749	42	31	was	be	AUX
bjos-8668749	42	32	firmly	firmly	ADV
bjos-8668749	42	33	anchored	anchor	VERB
bjos-8668749	42	34	to	to	ADP
bjos-8668749	42	35	the	the	DET
bjos-8668749	42	36	titanium	titanium	NOUN
bjos-8668749	42	37	implant	implant	ADJ
bjos-8668749	42	38	surface	surface	NOUN
bjos-8668749	42	39	on	on	ADP
bjos-8668749	42	40	a	a	DET
bjos-8668749	42	41	microscale	microscale	NOUN
bjos-8668749	42	42	.	.	PUNCT
bjos-8668749	43	1	as	as	SCONJ
bjos-8668749	43	2	time	time	NOUN
bjos-8668749	43	3	went	go	VERB
bjos-8668749	43	4	by	by	ADV
bjos-8668749	43	5	,	,	PUNCT
bjos-8668749	43	6	new	new	ADJ
bjos-8668749	43	7	researches	research	NOUN
bjos-8668749	43	8	emerged	emerge	VERB
bjos-8668749	43	9	and	and	CCONJ
bjos-8668749	43	10	new	new	ADJ
bjos-8668749	43	11	paradigms	paradigm	NOUN
bjos-8668749	43	12	began	begin	VERB
bjos-8668749	43	13	to	to	PART
bjos-8668749	43	14	be	be	AUX
bjos-8668749	43	15	considered	consider	VERB
bjos-8668749	43	16	,	,	PUNCT
bjos-8668749	43	17	such	such	ADJ
bjos-8668749	43	18	as	as	ADP
bjos-8668749	43	19	biocompatibility	biocompatibility	NOUN
bjos-8668749	43	20	.	.	PUNCT
bjos-8668749	44	1	thus	thus	ADV
bjos-8668749	44	2	,	,	PUNCT
bjos-8668749	44	3	the	the	DET
bjos-8668749	44	4	biocompatibility	biocompatibility	NOUN
bjos-8668749	44	5	conception	conception	NOUN
bjos-8668749	44	6	emerged	emerge	VERB
bjos-8668749	44	7	as	as	ADP
bjos-8668749	44	8	a	a	DET
bjos-8668749	44	9	primordial	primordial	ADJ
bjos-8668749	44	10	property	property	NOUN
bjos-8668749	44	11	for	for	ADP
bjos-8668749	44	12	the	the	DET
bjos-8668749	44	13	establishment	establishment	NOUN
bjos-8668749	44	14	of	of	ADP
bjos-8668749	44	15	an	an	DET
bjos-8668749	44	16	excellent	excellent	ADJ
bjos-8668749	44	17	interaction	interaction	NOUN
bjos-8668749	44	18	between	between	ADP
bjos-8668749	44	19	bone	bone	NOUN
bjos-8668749	44	20	tissue	tissue	NOUN
bjos-8668749	44	21	and	and	CCONJ
bjos-8668749	44	22	the	the	DET
bjos-8668749	44	23	biomaterial9	biomaterial9	PROPN
bjos-8668749	44	24	.	.	PUNCT
bjos-8668749	45	1	osseointegration	osseointegration	NOUN
bjos-8668749	45	2	process	process	NOUN
bjos-8668749	45	3	on	on	ADP
bjos-8668749	45	4	nanoscale	nanoscale	NOUN
bjos-8668749	45	5	allows	allow	VERB
bjos-8668749	45	6	for	for	ADP
bjos-8668749	45	7	the	the	DET
bjos-8668749	45	8	anchoring	anchoring	NOUN
bjos-8668749	45	9	of	of	ADP
bjos-8668749	45	10	proteins	protein	NOUN
bjos-8668749	45	11	between	between	ADP
bjos-8668749	45	12	the	the	DET
bjos-8668749	45	13	endosseous	endosseous	ADJ
bjos-8668749	45	14	implant	implant	NOUN
bjos-8668749	45	15	and	and	CCONJ
bjos-8668749	45	16	the	the	DET
bjos-8668749	45	17	bone	bone	NOUN
bjos-8668749	45	18	tissue	tissue	NOUN
bjos-8668749	45	19	.	.	PUNCT
bjos-8668749	46	1	this	this	PRON
bjos-8668749	46	2	is	be	AUX
bjos-8668749	46	3	so	so	SCONJ
bjos-8668749	46	4	that	that	SCONJ
bjos-8668749	46	5	it	it	PRON
bjos-8668749	46	6	can	can	AUX
bjos-8668749	46	7	support	support	VERB
bjos-8668749	46	8	the	the	DET
bjos-8668749	46	9	functional	functional	ADJ
bjos-8668749	46	10	loads	load	NOUN
bjos-8668749	46	11	of	of	ADP
bjos-8668749	46	12	mastication	mastication	NOUN
bjos-8668749	46	13	.	.	PUNCT
bjos-8668749	47	1	this	this	DET
bjos-8668749	47	2	process	process	NOUN
bjos-8668749	47	3	can	can	AUX
bjos-8668749	47	4	be	be	AUX
bjos-8668749	47	5	divided	divide	VERB
bjos-8668749	47	6	into	into	ADP
bjos-8668749	47	7	three	three	NUM
bjos-8668749	47	8	phases	phase	NOUN
bjos-8668749	47	9	:	:	PUNCT
bjos-8668749	47	10	osteoconduction	osteoconduction	NOUN
bjos-8668749	47	11	,	,	PUNCT
bjos-8668749	47	12	bone	bone	NOUN
bjos-8668749	47	13	formation	formation	NOUN
bjos-8668749	47	14	,	,	PUNCT
bjos-8668749	47	15	and	and	CCONJ
bjos-8668749	47	16	bone	bone	NOUN
bjos-8668749	47	17	remodeling4	remodeling4	NOUN
bjos-8668749	47	18	.	.	PUNCT
bjos-8668749	48	1	osteoconduction	osteoconduction	NOUN
bjos-8668749	48	2	is	be	AUX
bjos-8668749	48	3	a	a	DET
bjos-8668749	48	4	process	process	NOUN
bjos-8668749	48	5	defined	define	VERB
bjos-8668749	48	6	by	by	ADP
bjos-8668749	48	7	the	the	DET
bjos-8668749	48	8	migration	migration	NOUN
bjos-8668749	48	9	of	of	ADP
bjos-8668749	48	10	cells	cell	NOUN
bjos-8668749	48	11	from	from	ADP
bjos-8668749	48	12	the	the	DET
bjos-8668749	48	13	bone	bone	NOUN
bjos-8668749	48	14	extracellular	extracellular	ADJ
bjos-8668749	48	15	matrix	matrix	NOUN
bjos-8668749	48	16	to	to	ADP
bjos-8668749	48	17	the	the	DET
bjos-8668749	48	18	osseointegrable	osseointegrable	ADJ
bjos-8668749	48	19	implant	implant	ADJ
bjos-8668749	48	20	surface	surface	NOUN
bjos-8668749	48	21	.	.	PUNCT
bjos-8668749	49	1	this	this	DET
bjos-8668749	49	2	event	event	NOUN
bjos-8668749	49	3	occurs	occur	VERB
bjos-8668749	49	4	at	at	ADP
bjos-8668749	49	5	the	the	DET
bjos-8668749	49	6	level	level	NOUN
bjos-8668749	49	7	of	of	ADP
bjos-8668749	49	8	migration	migration	NOUN
bjos-8668749	49	9	,	,	PUNCT
bjos-8668749	49	10	attachment	attachment	NOUN
bjos-8668749	49	11	activity	activity	NOUN
bjos-8668749	49	12	,	,	PUNCT
bjos-8668749	49	13	proliferation	proliferation	NOUN
bjos-8668749	49	14	,	,	PUNCT
bjos-8668749	49	15	differentiation	differentiation	NOUN
bjos-8668749	49	16	,	,	PUNCT
bjos-8668749	49	17	and	and	CCONJ
bjos-8668749	49	18	bone	bone	NOUN
bjos-8668749	49	19	proteins	protein	NOUN
bjos-8668749	49	20	expression	expression	NOUN
bjos-8668749	49	21	such	such	ADJ
bjos-8668749	49	22	as	as	ADP
bjos-8668749	49	23	osteocalcin	osteocalcin	NOUN
bjos-8668749	49	24	,	,	PUNCT
bjos-8668749	49	25	osteopontin	osteopontin	NOUN
bjos-8668749	49	26	,	,	PUNCT
bjos-8668749	49	27	and	and	CCONJ
bjos-8668749	49	28	fibronectin10	fibronectin10	NOUN
bjos-8668749	49	29	.	.	PUNCT
bjos-8668749	50	1	however	however	ADV
bjos-8668749	50	2	,	,	PUNCT
bjos-8668749	50	3	osteoconduction	osteoconduction	NOUN
bjos-8668749	50	4	is	be	AUX
bjos-8668749	50	5	already	already	ADV
bjos-8668749	50	6	part	part	NOUN
bjos-8668749	50	7	of	of	ADP
bjos-8668749	50	8	the	the	DET
bjos-8668749	50	9	natural	natural	ADJ
bjos-8668749	50	10	bone	bone	NOUN
bjos-8668749	50	11	remodeling	remodeling	NOUN
bjos-8668749	50	12	process	process	NOUN
bjos-8668749	50	13	,	,	PUNCT
bjos-8668749	50	14	so	so	CCONJ
bjos-8668749	50	15	the	the	DET
bjos-8668749	50	16	difference	difference	NOUN
bjos-8668749	50	17	is	be	AUX
bjos-8668749	50	18	that	that	SCONJ
bjos-8668749	50	19	in	in	ADP
bjos-8668749	50	20	implant	implant	ADJ
bjos-8668749	50	21	installation	installation	NOUN
bjos-8668749	50	22	,	,	PUNCT
bjos-8668749	50	23	there	there	PRON
bjos-8668749	50	24	is	be	VERB
bjos-8668749	50	25	the	the	DET
bjos-8668749	50	26	presence	presence	NOUN
bjos-8668749	50	27	of	of	ADP
bjos-8668749	50	28	a	a	DET
bjos-8668749	50	29	blood	blood	NOUN
bjos-8668749	50	30	clot	clot	NOUN
bjos-8668749	50	31	in	in	ADP
bjos-8668749	50	32	contact	contact	NOUN
bjos-8668749	50	33	with	with	ADP
bjos-8668749	50	34	the	the	DET
bjos-8668749	50	35	implant	implant	ADJ
bjos-8668749	50	36	surface	surface	NOUN
bjos-8668749	50	37	in	in	ADP
bjos-8668749	50	38	peri	peri	NOUN
bjos-8668749	50	39	-	-	PUNCT
bjos-8668749	50	40	implant	implant	ADJ
bjos-8668749	50	41	repair	repair	NOUN
bjos-8668749	50	42	.	.	PUNCT
bjos-8668749	51	1	thus	thus	ADV
bjos-8668749	51	2	,	,	PUNCT
bjos-8668749	51	3	it	it	PRON
bjos-8668749	51	4	can	can	AUX
bjos-8668749	51	5	be	be	AUX
bjos-8668749	51	6	seen	see	VERB
bjos-8668749	51	7	that	that	PRON
bjos-8668749	51	8	angiogenesis	angiogenesis	NOUN
bjos-8668749	51	9	precedes	precede	VERB
bjos-8668749	51	10	osteogenesis	osteogenesis	NOUN
bjos-8668749	51	11	in	in	ADP
bjos-8668749	51	12	both	both	DET
bjos-8668749	51	13	bone	bone	NOUN
bjos-8668749	51	14	regeneration	regeneration	NOUN
bjos-8668749	51	15	and	and	CCONJ
bjos-8668749	51	16	remodeling11	remodeling11	NOUN
bjos-8668749	51	17	.	.	PUNCT
bjos-8668749	52	1	as	as	SCONJ
bjos-8668749	52	2	bone	bone	NOUN
bjos-8668749	52	3	tissue	tissue	NOUN
bjos-8668749	52	4	cells	cell	NOUN
bjos-8668749	52	5	begin	begin	VERB
bjos-8668749	52	6	to	to	PART
bjos-8668749	52	7	migrate	migrate	VERB
bjos-8668749	52	8	to	to	ADP
bjos-8668749	52	9	the	the	DET
bjos-8668749	52	10	implant	implant	NOUN
bjos-8668749	52	11	and	and	CCONJ
bjos-8668749	52	12	approach	approach	VERB
bjos-8668749	52	13	the	the	DET
bjos-8668749	52	14	surface	surface	NOUN
bjos-8668749	52	15	,	,	PUNCT
bjos-8668749	52	16	these	these	DET
bjos-8668749	52	17	cells	cell	NOUN
bjos-8668749	52	18	start	start	VERB
bjos-8668749	52	19	to	to	PART
bjos-8668749	52	20	differentiate	differentiate	VERB
bjos-8668749	52	21	.	.	PUNCT
bjos-8668749	53	1	the	the	DET
bjos-8668749	53	2	osseintegration	osseintegration	NOUN
bjos-8668749	53	3	process	process	NOUN
bjos-8668749	53	4	is	be	AUX
bjos-8668749	53	5	initiated	initiate	VERB
bjos-8668749	53	6	by	by	ADP
bjos-8668749	53	7	adsorption	adsorption	NOUN
bjos-8668749	53	8	of	of	ADP
bjos-8668749	53	9	the	the	DET
bjos-8668749	53	10	blood	blood	NOUN
bjos-8668749	53	11	plasma	plasma	NOUN
bjos-8668749	53	12	proteins	protein	NOUN
bjos-8668749	53	13	,	,	PUNCT
bjos-8668749	53	14	but	but	CCONJ
bjos-8668749	53	15	the	the	DET
bjos-8668749	53	16	phenomena	phenomenon	NOUN
bjos-8668749	53	17	involved	involve	VERB
bjos-8668749	53	18	are	be	AUX
bjos-8668749	53	19	slow	slow	ADJ
bjos-8668749	53	20	and	and	CCONJ
bjos-8668749	53	21	it	it	PRON
bjos-8668749	53	22	takes	take	VERB
bjos-8668749	53	23	several	several	ADJ
bjos-8668749	53	24	days	day	NOUN
bjos-8668749	53	25	for	for	ADP
bjos-8668749	53	26	the	the	DET
bjos-8668749	53	27	osteogenic	osteogenic	ADJ
bjos-8668749	53	28	deposition	deposition	NOUN
bjos-8668749	53	29	to	to	PART
bjos-8668749	53	30	reach	reach	VERB
bjos-8668749	53	31	the	the	DET
bjos-8668749	53	32	implant	implant	ADJ
bjos-8668749	53	33	surface11	surface11	NOUN
bjos-8668749	53	34	-	-	PUNCT
bjos-8668749	53	35	13	13	NUM
bjos-8668749	53	36	.	.	PUNCT
bjos-8668749	54	1	when	when	SCONJ
bjos-8668749	54	2	the	the	DET
bjos-8668749	54	3	biocompatibility	biocompatibility	NOUN
bjos-8668749	54	4	principle	principle	NOUN
bjos-8668749	54	5	is	be	AUX
bjos-8668749	54	6	not	not	PART
bjos-8668749	54	7	fully	fully	ADV
bjos-8668749	54	8	favorable	favorable	ADJ
bjos-8668749	54	9	,	,	PUNCT
bjos-8668749	54	10	the	the	DET
bjos-8668749	54	11	fibrointegration	fibrointegration	NOUN
bjos-8668749	54	12	process	process	NOUN
bjos-8668749	54	13	occurs	occur	VERB
bjos-8668749	54	14	.	.	PUNCT
bjos-8668749	55	1	cell	cell	NOUN
bjos-8668749	55	2	proliferation	proliferation	NOUN
bjos-8668749	55	3	,	,	PUNCT
bjos-8668749	55	4	tissue	tissue	NOUN
bjos-8668749	55	5	regeneration	regeneration	NOUN
bjos-8668749	55	6	,	,	PUNCT
bjos-8668749	55	7	and	and	CCONJ
bjos-8668749	55	8	the	the	DET
bjos-8668749	55	9	normal	normal	ADJ
bjos-8668749	55	10	bone	bone	NOUN
bjos-8668749	55	11	tissue	tissue	NOUN
bjos-8668749	55	12	reconstitution	reconstitution	NOUN
bjos-8668749	55	13	do	do	AUX
bjos-8668749	55	14	not	not	PART
bjos-8668749	55	15	occur	occur	VERB
bjos-8668749	55	16	.	.	PUNCT
bjos-8668749	56	1	the	the	DET
bjos-8668749	56	2	tissue	tissue	NOUN
bjos-8668749	56	3	around	around	ADP
bjos-8668749	56	4	the	the	DET
bjos-8668749	56	5	implant	implant	NOUN
bjos-8668749	56	6	is	be	AUX
bjos-8668749	56	7	replaced	replace	VERB
bjos-8668749	56	8	by	by	ADP
bjos-8668749	56	9	scar	scar	ADJ
bjos-8668749	56	10	tissue	tissue	NOUN
bjos-8668749	56	11	,	,	PUNCT
bjos-8668749	56	12	forming	form	VERB
bjos-8668749	56	13	a	a	DET
bjos-8668749	56	14	fibrous	fibrous	ADJ
bjos-8668749	56	15	connective	connective	ADJ
bjos-8668749	56	16	tissue	tissue	NOUN
bjos-8668749	56	17	capsule1	capsule1	NOUN
bjos-8668749	56	18	.	.	PUNCT
bjos-8668749	57	1	thus	thus	ADV
bjos-8668749	57	2	,	,	PUNCT
bjos-8668749	57	3	after	after	SCONJ
bjos-8668749	57	4	the	the	DET
bjos-8668749	57	5	implant	implant	NOUN
bjos-8668749	57	6	is	be	AUX
bjos-8668749	57	7	inserted	insert	VERB
bjos-8668749	57	8	into	into	ADP
bjos-8668749	57	9	the	the	DET
bjos-8668749	57	10	gnatic	gnatic	ADJ
bjos-8668749	57	11	bones	bone	NOUN
bjos-8668749	57	12	,	,	PUNCT
bjos-8668749	57	13	a	a	DET
bjos-8668749	57	14	cascade	cascade	NOUN
bjos-8668749	57	15	of	of	ADP
bjos-8668749	57	16	biological	biological	ADJ
bjos-8668749	57	17	responses	response	NOUN
bjos-8668749	57	18	will	will	AUX
bjos-8668749	57	19	sustain	sustain	VERB
bjos-8668749	57	20	the	the	DET
bjos-8668749	57	21	bone	bone	NOUN
bjos-8668749	57	22	integration	integration	NOUN
bjos-8668749	57	23	process	process	NOUN
bjos-8668749	57	24	.	.	PUNCT
bjos-8668749	58	1	immune	immune	ADJ
bjos-8668749	58	2	and	and	CCONJ
bjos-8668749	58	3	inflammatory	inflammatory	ADJ
bjos-8668749	58	4	responses	response	NOUN
bjos-8668749	58	5	associated	associate	VERB
bjos-8668749	58	6	with	with	ADP
bjos-8668749	58	7	the	the	DET
bjos-8668749	58	8	complement	complement	NOUN
bjos-8668749	58	9	system	system	NOUN
bjos-8668749	58	10	are	be	AUX
bjos-8668749	58	11	mediated	mediate	VERB
bjos-8668749	58	12	in	in	ADP
bjos-8668749	58	13	the	the	DET
bjos-8668749	58	14	osteoconduction	osteoconduction	NOUN
bjos-8668749	58	15	space4	space4	NOUN
bjos-8668749	58	16	.	.	PUNCT
bjos-8668749	59	1	therefore	therefore	ADV
bjos-8668749	59	2	,	,	PUNCT
bjos-8668749	59	3	seconds	second	NOUN
bjos-8668749	59	4	after	after	ADP
bjos-8668749	59	5	implant	implant	ADJ
bjos-8668749	59	6	insertion	insertion	NOUN
bjos-8668749	59	7	,	,	PUNCT
bjos-8668749	59	8	a	a	DET
bjos-8668749	59	9	temporary	temporary	ADJ
bjos-8668749	59	10	matrix	matrix	NOUN
bjos-8668749	59	11	of	of	ADP
bjos-8668749	59	12	fibrin	fibrin	NOUN
bjos-8668749	59	13	and	and	CCONJ
bjos-8668749	59	14	plasma	plasma	NOUN
bjos-8668749	59	15	proteins	protein	NOUN
bjos-8668749	59	16	(	(	PUNCT
bjos-8668749	59	17	2	2	NUM
bjos-8668749	59	18	-	-	SYM
bjos-8668749	59	19	5	5	NUM
bjos-8668749	59	20	nm	nm	NOUN
bjos-8668749	59	21	)	)	PUNCT
bjos-8668749	59	22	is	be	AUX
bjos-8668749	59	23	formed2	formed2	NOUN
bjos-8668749	59	24	.	.	PUNCT
bjos-8668749	60	1	based	base	VERB
bjos-8668749	60	2	on	on	ADP
bjos-8668749	60	3	this	this	DET
bjos-8668749	60	4	process	process	NOUN
bjos-8668749	60	5	and	and	CCONJ
bjos-8668749	60	6	on	on	ADP
bjos-8668749	60	7	the	the	DET
bjos-8668749	60	8	biocompatibility	biocompatibility	NOUN
bjos-8668749	60	9	response	response	NOUN
bjos-8668749	60	10	of	of	ADP
bjos-8668749	60	11	the	the	DET
bjos-8668749	60	12	dental	dental	ADJ
bjos-8668749	60	13	implant	implant	NOUN
bjos-8668749	60	14	with	with	ADP
bjos-8668749	60	15	the	the	DET
bjos-8668749	60	16	surrounding	surround	VERB
bjos-8668749	60	17	tissues	tissue	NOUN
bjos-8668749	60	18	,	,	PUNCT
bjos-8668749	60	19	the	the	DET
bjos-8668749	60	20	integration	integration	NOUN
bjos-8668749	60	21	process	process	NOUN
bjos-8668749	60	22	will	will	AUX
bjos-8668749	60	23	be	be	AUX
bjos-8668749	60	24	determined	determine	VERB
bjos-8668749	60	25	.	.	PUNCT
bjos-8668749	61	1	bone	bone	NOUN
bjos-8668749	61	2	extracellular	extracellular	ADJ
bjos-8668749	61	3	matrix	matrix	NOUN
bjos-8668749	61	4	proteins	protein	NOUN
bjos-8668749	61	5	the	the	DET
bjos-8668749	61	6	osseointegration	osseointegration	NOUN
bjos-8668749	61	7	concept	concept	NOUN
bjos-8668749	61	8	used	use	VERB
bjos-8668749	61	9	to	to	PART
bjos-8668749	61	10	be	be	AUX
bjos-8668749	61	11	associated	associate	VERB
bjos-8668749	61	12	with	with	ADP
bjos-8668749	61	13	the	the	DET
bjos-8668749	61	14	cell	cell	NOUN
bjos-8668749	61	15	’s	’s	PART
bjos-8668749	61	16	adhesion	adhesion	NOUN
bjos-8668749	61	17	to	to	ADP
bjos-8668749	61	18	the	the	DET
bjos-8668749	61	19	implant	implant	ADJ
bjos-8668749	61	20	surface	surface	NOUN
bjos-8668749	61	21	.	.	PUNCT
bjos-8668749	62	1	today	today	NOUN
bjos-8668749	62	2	,	,	PUNCT
bjos-8668749	62	3	this	this	DET
bjos-8668749	62	4	concept	concept	NOUN
bjos-8668749	62	5	involves	involve	VERB
bjos-8668749	62	6	the	the	DET
bjos-8668749	62	7	bone	bone	NOUN
bjos-8668749	62	8	cells	cell	NOUN
bjos-8668749	62	9	contact	contact	NOUN
bjos-8668749	62	10	with	with	ADP
bjos-8668749	62	11	the	the	DET
bjos-8668749	62	12	implant	implant	ADJ
bjos-8668749	62	13	4	4	NUM
bjos-8668749	62	14	nascimento	nascimento	PROPN
bjos-8668749	62	15	et	et	PROPN
bjos-8668749	62	16	al	al	PROPN
bjos-8668749	62	17	.	.	PROPN
bjos-8668749	62	18	braz	braz	PROPN
bjos-8668749	62	19	j	j	PROPN
bjos-8668749	62	20	oral	oral	PROPN
bjos-8668749	62	21	sci	sci	PROPN
bjos-8668749	62	22	.	.	PUNCT
bjos-8668749	63	1	2023;22	2023;22	NUM
bjos-8668749	63	2	:	:	PUNCT
bjos-8668749	63	3	e238749	e238749	PROPN
bjos-8668749	63	4	surface	surface	NOUN
bjos-8668749	63	5	via	via	ADP
bjos-8668749	63	6	a	a	DET
bjos-8668749	63	7	protein	protein	NOUN
bjos-8668749	63	8	interface14	interface14	ADJ
bjos-8668749	63	9	.	.	PUNCT
bjos-8668749	64	1	osseointegration	osseointegration	NOUN
bjos-8668749	64	2	is	be	AUX
bjos-8668749	64	3	not	not	PART
bjos-8668749	64	4	characterized	characterize	VERB
bjos-8668749	64	5	by	by	ADP
bjos-8668749	64	6	bone	bone	NOUN
bjos-8668749	64	7	matrix	matrix	NOUN
bjos-8668749	64	8	contact	contact	NOUN
bjos-8668749	64	9	with	with	ADP
bjos-8668749	64	10	the	the	DET
bjos-8668749	64	11	implant	implant	ADJ
bjos-8668749	64	12	surface	surface	NOUN
bjos-8668749	64	13	.	.	PUNCT
bjos-8668749	65	1	the	the	DET
bjos-8668749	65	2	process	process	NOUN
bjos-8668749	65	3	begins	begin	VERB
bjos-8668749	65	4	with	with	ADP
bjos-8668749	65	5	the	the	DET
bjos-8668749	65	6	deposition	deposition	NOUN
bjos-8668749	65	7	of	of	ADP
bjos-8668749	65	8	extracellular	extracellular	ADJ
bjos-8668749	65	9	matrix	matrix	NOUN
bjos-8668749	65	10	proteins	protein	NOUN
bjos-8668749	65	11	on	on	ADP
bjos-8668749	65	12	the	the	DET
bjos-8668749	65	13	implant	implant	ADJ
bjos-8668749	65	14	surface	surface	NOUN
bjos-8668749	65	15	.	.	PUNCT
bjos-8668749	66	1	after	after	ADP
bjos-8668749	66	2	adsorption	adsorption	NOUN
bjos-8668749	66	3	,	,	PUNCT
bjos-8668749	66	4	protein	protein	NOUN
bjos-8668749	66	5	adhesion	adhesion	NOUN
bjos-8668749	66	6	to	to	ADP
bjos-8668749	66	7	the	the	DET
bjos-8668749	66	8	implant	implant	ADJ
bjos-8668749	66	9	surface	surface	NOUN
bjos-8668749	66	10	occurs	occur	VERB
bjos-8668749	66	11	,	,	PUNCT
bjos-8668749	66	12	followed	follow	VERB
bjos-8668749	66	13	by	by	ADP
bjos-8668749	66	14	protein	protein	NOUN
bjos-8668749	66	15	interaction	interaction	NOUN
bjos-8668749	66	16	with	with	ADP
bjos-8668749	66	17	undifferentiated	undifferentiated	ADJ
bjos-8668749	66	18	cells	cell	NOUN
bjos-8668749	66	19	via	via	ADP
bjos-8668749	66	20	specific	specific	ADJ
bjos-8668749	66	21	receptors15	receptors15	NOUN
bjos-8668749	66	22	.	.	PUNCT
bjos-8668749	67	1	in	in	ADP
bjos-8668749	67	2	protein	protein	NOUN
bjos-8668749	67	3	-	-	PUNCT
bjos-8668749	67	4	cell	cell	NOUN
bjos-8668749	67	5	interaction	interaction	NOUN
bjos-8668749	67	6	,	,	PUNCT
bjos-8668749	67	7	signal	signal	NOUN
bjos-8668749	67	8	-	-	PUNCT
bjos-8668749	67	9	transduction	transduction	NOUN
bjos-8668749	67	10	mechanisms	mechanism	NOUN
bjos-8668749	67	11	are	be	AUX
bjos-8668749	67	12	mediated	mediate	VERB
bjos-8668749	67	13	by	by	ADP
bjos-8668749	67	14	proteins	protein	NOUN
bjos-8668749	67	15	in	in	ADP
bjos-8668749	67	16	the	the	DET
bjos-8668749	67	17	cytoplasm	cytoplasm	NOUN
bjos-8668749	67	18	,	,	PUNCT
bjos-8668749	67	19	leading	lead	VERB
bjos-8668749	67	20	to	to	ADP
bjos-8668749	67	21	cell	cell	NOUN
bjos-8668749	67	22	differentiation	differentiation	NOUN
bjos-8668749	67	23	,	,	PUNCT
bjos-8668749	67	24	attachment	attachment	NOUN
bjos-8668749	67	25	and	and	CCONJ
bjos-8668749	67	26	propagation	propagation	NOUN
bjos-8668749	67	27	on	on	ADP
bjos-8668749	67	28	the	the	DET
bjos-8668749	67	29	implant	implant	ADJ
bjos-8668749	67	30	surface16	surface16	NOUN
bjos-8668749	67	31	.	.	PUNCT
bjos-8668749	68	1	protein	protein	NOUN
bjos-8668749	68	2	’s	’s	PART
bjos-8668749	68	3	adsorption	adsorption	NOUN
bjos-8668749	68	4	on	on	ADP
bjos-8668749	68	5	planar	planar	ADJ
bjos-8668749	68	6	surfaces	surface	NOUN
bjos-8668749	68	7	occurs	occur	VERB
bjos-8668749	68	8	almost	almost	ADV
bjos-8668749	68	9	instantaneously	instantaneously	ADV
bjos-8668749	68	10	after	after	ADP
bjos-8668749	68	11	implantation	implantation	NOUN
bjos-8668749	68	12	,	,	PUNCT
bjos-8668749	68	13	forming	form	VERB
bjos-8668749	68	14	a	a	DET
bjos-8668749	68	15	2	2	NUM
bjos-8668749	68	16	-	-	SYM
bjos-8668749	68	17	5	5	NUM
bjos-8668749	68	18	nm	nm	NOUN
bjos-8668749	68	19	layer	layer	NOUN
bjos-8668749	68	20	through	through	ADP
bjos-8668749	68	21	molecular	molecular	ADJ
bjos-8668749	68	22	-	-	PUNCT
bjos-8668749	68	23	scale	scale	NOUN
bjos-8668749	68	24	interactions	interaction	NOUN
bjos-8668749	68	25	with	with	ADP
bjos-8668749	68	26	the	the	DET
bjos-8668749	68	27	substrate17	substrate17	NOUN
bjos-8668749	68	28	.	.	PUNCT
bjos-8668749	69	1	the	the	DET
bjos-8668749	69	2	bone	bone	NOUN
bjos-8668749	69	3	extracellular	extracellular	ADJ
bjos-8668749	69	4	matrix	matrix	NOUN
bjos-8668749	69	5	provides	provide	VERB
bjos-8668749	69	6	a	a	DET
bjos-8668749	69	7	suitable	suitable	ADJ
bjos-8668749	69	8	environment	environment	NOUN
bjos-8668749	69	9	for	for	ADP
bjos-8668749	69	10	the	the	DET
bjos-8668749	69	11	growth	growth	NOUN
bjos-8668749	69	12	and	and	CCONJ
bjos-8668749	69	13	differentiation	differentiation	NOUN
bjos-8668749	69	14	of	of	ADP
bjos-8668749	69	15	various	various	ADJ
bjos-8668749	69	16	body	body	NOUN
bjos-8668749	69	17	cell	cell	NOUN
bjos-8668749	69	18	types	type	NOUN
bjos-8668749	69	19	,	,	PUNCT
bjos-8668749	69	20	and	and	CCONJ
bjos-8668749	69	21	has	have	VERB
bjos-8668749	69	22	various	various	ADJ
bjos-8668749	69	23	proportions	proportion	NOUN
bjos-8668749	69	24	of	of	ADP
bjos-8668749	69	25	proteins	protein	NOUN
bjos-8668749	69	26	that	that	PRON
bjos-8668749	69	27	participate	participate	VERB
bjos-8668749	69	28	in	in	ADP
bjos-8668749	69	29	the	the	DET
bjos-8668749	69	30	osseointegration	osseointegration	NOUN
bjos-8668749	69	31	process18	process18	NOUN
bjos-8668749	69	32	.	.	PUNCT
bjos-8668749	70	1	among	among	ADP
bjos-8668749	70	2	the	the	DET
bjos-8668749	70	3	matrix	matrix	NOUN
bjos-8668749	70	4	extracellular	extracellular	ADJ
bjos-8668749	70	5	constituents	constituent	NOUN
bjos-8668749	70	6	,	,	PUNCT
bjos-8668749	70	7	the	the	DET
bjos-8668749	70	8	various	various	ADJ
bjos-8668749	70	9	macromolecules	macromolecule	NOUN
bjos-8668749	70	10	such	such	ADJ
bjos-8668749	70	11	as	as	ADP
bjos-8668749	70	12	glycoproteins	glycoprotein	NOUN
bjos-8668749	70	13	,	,	PUNCT
bjos-8668749	70	14	proteoglycans	proteoglycan	NOUN
bjos-8668749	70	15	,	,	PUNCT
bjos-8668749	70	16	glycosaminoglycans	glycosaminoglycan	NOUN
bjos-8668749	70	17	and	and	CCONJ
bjos-8668749	70	18	other	other	ADJ
bjos-8668749	70	19	proteins	protein	NOUN
bjos-8668749	70	20	are	be	AUX
bjos-8668749	70	21	essential	essential	ADJ
bjos-8668749	70	22	in	in	ADP
bjos-8668749	70	23	the	the	DET
bjos-8668749	70	24	biomaterial	biomaterial	ADJ
bjos-8668749	70	25	recognition	recognition	NOUN
bjos-8668749	70	26	mechanisms	mechanism	NOUN
bjos-8668749	70	27	and	and	CCONJ
bjos-8668749	70	28	interactions	interaction	NOUN
bjos-8668749	70	29	.	.	PUNCT
bjos-8668749	71	1	glycoproteins	glycoprotein	NOUN
bjos-8668749	71	2	are	be	AUX
bjos-8668749	71	3	proteins	protein	NOUN
bjos-8668749	71	4	that	that	PRON
bjos-8668749	71	5	have	have	VERB
bjos-8668749	71	6	oligosaccharide	oligosaccharide	NOUN
bjos-8668749	71	7	chains	chain	NOUN
bjos-8668749	71	8	attached	attach	VERB
bjos-8668749	71	9	to	to	ADP
bjos-8668749	71	10	polypeptide	polypeptide	ADJ
bjos-8668749	71	11	side	side	NOUN
bjos-8668749	71	12	chains	chain	NOUN
bjos-8668749	71	13	.	.	PUNCT
bjos-8668749	72	1	glycoproteins	glycoprotein	NOUN
bjos-8668749	72	2	interact	interact	VERB
bjos-8668749	72	3	between	between	ADP
bjos-8668749	72	4	the	the	DET
bjos-8668749	72	5	extracellular	extracellular	ADJ
bjos-8668749	72	6	matrix	matrix	NOUN
bjos-8668749	72	7	components	component	NOUN
bjos-8668749	72	8	,	,	PUNCT
bjos-8668749	72	9	help	help	NOUN
bjos-8668749	72	10	in	in	ADP
bjos-8668749	72	11	the	the	DET
bjos-8668749	72	12	structure	structure	NOUN
bjos-8668749	72	13	formation	formation	NOUN
bjos-8668749	72	14	,	,	PUNCT
bjos-8668749	72	15	promote	promote	VERB
bjos-8668749	72	16	adhesion	adhesion	NOUN
bjos-8668749	72	17	and	and	CCONJ
bjos-8668749	72	18	cell	cell	NOUN
bjos-8668749	72	19	signaling19	signaling19	NOUN
bjos-8668749	72	20	.	.	PUNCT
bjos-8668749	73	1	the	the	DET
bjos-8668749	73	2	main	main	ADJ
bjos-8668749	73	3	matrix	matrix	NOUN
bjos-8668749	73	4	extracellular	extracellular	ADJ
bjos-8668749	73	5	proteins	protein	NOUN
bjos-8668749	73	6	are	be	AUX
bjos-8668749	73	7	fibronectin	fibronectin	NOUN
bjos-8668749	73	8	,	,	PUNCT
bjos-8668749	73	9	vitronectin	vitronectin	NOUN
bjos-8668749	73	10	,	,	PUNCT
bjos-8668749	73	11	laminin	laminin	NOUN
bjos-8668749	73	12	,	,	PUNCT
bjos-8668749	73	13	osteonectin	osteonectin	INTJ
bjos-8668749	73	14	,	,	PUNCT
bjos-8668749	73	15	entactin	entactin	ADV
bjos-8668749	73	16	,	,	PUNCT
bjos-8668749	73	17	tenascin	tenascin	PROPN
bjos-8668749	73	18	,	,	PUNCT
bjos-8668749	73	19	osteopontin	osteopontin	PROPN
bjos-8668749	73	20	,	,	PUNCT
bjos-8668749	73	21	thrombospondin	thrombospondin	NOUN
bjos-8668749	73	22	,	,	PUNCT
bjos-8668749	73	23	collagen	collagen	NOUN
bjos-8668749	73	24	,	,	PUNCT
bjos-8668749	73	25	entactin	entactin	NOUN
bjos-8668749	73	26	and	and	CCONJ
bjos-8668749	73	27	chondronectin	chondronectin	PROPN
bjos-8668749	73	28	.	.	PUNCT
bjos-8668749	74	1	the	the	DET
bjos-8668749	74	2	top	top	ADJ
bjos-8668749	74	3	five	five	NUM
bjos-8668749	74	4	are	be	AUX
bjos-8668749	74	5	adhesive	adhesive	ADJ
bjos-8668749	74	6	proteins	protein	NOUN
bjos-8668749	74	7	and	and	CCONJ
bjos-8668749	74	8	have	have	VERB
bjos-8668749	74	9	a	a	DET
bjos-8668749	74	10	particular	particular	ADJ
bjos-8668749	74	11	function	function	NOUN
bjos-8668749	74	12	of	of	ADP
bjos-8668749	74	13	interest	interest	NOUN
bjos-8668749	74	14	in	in	ADP
bjos-8668749	74	15	the	the	DET
bjos-8668749	74	16	implants	implant	NOUN
bjos-8668749	74	17	osseointegration	osseointegration	NOUN
bjos-8668749	74	18	.	.	PUNCT
bjos-8668749	75	1	they	they	PRON
bjos-8668749	75	2	can	can	AUX
bjos-8668749	75	3	bind	bind	VERB
bjos-8668749	75	4	to	to	ADP
bjos-8668749	75	5	cell	cell	NOUN
bjos-8668749	75	6	surface	surface	NOUN
bjos-8668749	75	7	proteins	protein	NOUN
bjos-8668749	75	8	(	(	PUNCT
bjos-8668749	75	9	integrins	integrin	NOUN
bjos-8668749	75	10	)	)	PUNCT
bjos-8668749	75	11	,	,	PUNCT
bjos-8668749	75	12	collagen	collagen	NOUN
bjos-8668749	75	13	fibers	fiber	NOUN
bjos-8668749	75	14	,	,	PUNCT
bjos-8668749	75	15	and	and	CCONJ
bjos-8668749	75	16	other	other	ADJ
bjos-8668749	75	17	proteoglycans19,20	proteoglycans19,20	NOUN
bjos-8668749	75	18	.	.	PUNCT
bjos-8668749	75	19	fibronectin	fibronectin	NOUN
bjos-8668749	75	20	and	and	CCONJ
bjos-8668749	75	21	vitronectin	vitronectin	NOUN
bjos-8668749	75	22	are	be	AUX
bjos-8668749	75	23	extracellular	extracellular	ADJ
bjos-8668749	75	24	adhesion	adhesion	NOUN
bjos-8668749	75	25	proteins	protein	NOUN
bjos-8668749	75	26	,	,	PUNCT
bjos-8668749	75	27	they	they	PRON
bjos-8668749	75	28	induce	induce	VERB
bjos-8668749	75	29	the	the	DET
bjos-8668749	75	30	actin	actin	NOUN
bjos-8668749	75	31	microfilaments	microfilament	NOUN
bjos-8668749	75	32	reorganization	reorganization	NOUN
bjos-8668749	75	33	inside	inside	ADP
bjos-8668749	75	34	the	the	DET
bjos-8668749	75	35	cells	cell	NOUN
bjos-8668749	75	36	and	and	CCONJ
bjos-8668749	75	37	transmit	transmit	VERB
bjos-8668749	75	38	messages	message	NOUN
bjos-8668749	75	39	for	for	ADP
bjos-8668749	75	40	cell	cell	NOUN
bjos-8668749	75	41	adhesion	adhesion	NOUN
bjos-8668749	75	42	and	and	CCONJ
bjos-8668749	75	43	dissemination	dissemination	NOUN
bjos-8668749	75	44	to	to	PART
bjos-8668749	75	45	occur	occur	VERB
bjos-8668749	75	46	,	,	PUNCT
bjos-8668749	75	47	which	which	PRON
bjos-8668749	75	48	in	in	ADP
bjos-8668749	75	49	turn	turn	NOUN
bjos-8668749	75	50	affects	affect	VERB
bjos-8668749	75	51	cell	cell	NOUN
bjos-8668749	75	52	morphology	morphology	NOUN
bjos-8668749	75	53	and	and	CCONJ
bjos-8668749	75	54	migration	migration	NOUN
bjos-8668749	75	55	.	.	PUNCT
bjos-8668749	76	1	they	they	PRON
bjos-8668749	76	2	favor	favor	VERB
bjos-8668749	76	3	cell	cell	NOUN
bjos-8668749	76	4	adhesion	adhesion	NOUN
bjos-8668749	76	5	,	,	PUNCT
bjos-8668749	76	6	proliferation	proliferation	NOUN
bjos-8668749	76	7	,	,	PUNCT
bjos-8668749	76	8	and	and	CCONJ
bjos-8668749	76	9	differentiation	differentiation	NOUN
bjos-8668749	76	10	by	by	ADP
bjos-8668749	76	11	interacting	interact	VERB
bjos-8668749	76	12	with	with	ADP
bjos-8668749	76	13	specific	specific	ADJ
bjos-8668749	76	14	integrins	integrin	NOUN
bjos-8668749	76	15	.	.	PUNCT
bjos-8668749	77	1	these	these	DET
bjos-8668749	77	2	interactions	interaction	NOUN
bjos-8668749	77	3	are	be	AUX
bjos-8668749	77	4	essential	essential	ADJ
bjos-8668749	77	5	in	in	ADP
bjos-8668749	77	6	the	the	DET
bjos-8668749	77	7	mechanisms	mechanism	NOUN
bjos-8668749	77	8	surrounding	surround	VERB
bjos-8668749	77	9	implant	implant	ADJ
bjos-8668749	77	10	osseointegration15	osseointegration15	NOUN
bjos-8668749	77	11	-	-	PUNCT
bjos-8668749	77	12	20	20	NUM
bjos-8668749	77	13	.	.	PUNCT
bjos-8668749	78	1	the	the	DET
bjos-8668749	78	2	role	role	NOUN
bjos-8668749	78	3	of	of	ADP
bjos-8668749	78	4	integrin	integrin	NOUN
bjos-8668749	78	5	in	in	ADP
bjos-8668749	78	6	the	the	DET
bjos-8668749	78	7	osseointegration	osseointegration	NOUN
bjos-8668749	78	8	process	process	NOUN
bjos-8668749	78	9	integrin	integrin	NOUN
bjos-8668749	78	10	is	be	AUX
bjos-8668749	78	11	a	a	DET
bjos-8668749	78	12	transmembrane	transmembrane	ADJ
bjos-8668749	78	13	protein	protein	NOUN
bjos-8668749	78	14	that	that	PRON
bjos-8668749	78	15	belongs	belong	VERB
bjos-8668749	78	16	to	to	ADP
bjos-8668749	78	17	the	the	DET
bjos-8668749	78	18	extracellular	extracellular	ADJ
bjos-8668749	78	19	matrix	matrix	NOUN
bjos-8668749	78	20	that	that	PRON
bjos-8668749	78	21	binds	bind	VERB
bjos-8668749	78	22	to	to	ADP
bjos-8668749	78	23	the	the	DET
bjos-8668749	78	24	intracellular	intracellular	ADJ
bjos-8668749	78	25	cytoskeleton	cytoskeleton	NOUN
bjos-8668749	78	26	.	.	PUNCT
bjos-8668749	79	1	each	each	DET
bjos-8668749	79	2	integrin	integrin	NOUN
bjos-8668749	79	3	types	type	NOUN
bjos-8668749	79	4	has	have	VERB
bjos-8668749	79	5	a	a	DET
bjos-8668749	79	6	specificity	specificity	NOUN
bjos-8668749	79	7	,	,	PUNCT
bjos-8668749	79	8	but	but	CCONJ
bjos-8668749	79	9	most	most	ADJ
bjos-8668749	79	10	of	of	ADP
bjos-8668749	79	11	them	they	PRON
bjos-8668749	79	12	bind	bind	VERB
bjos-8668749	79	13	to	to	ADP
bjos-8668749	79	14	the	the	DET
bjos-8668749	79	15	actin	actin	NOUN
bjos-8668749	79	16	filaments	filament	NOUN
bjos-8668749	79	17	through	through	ADP
bjos-8668749	79	18	an	an	DET
bjos-8668749	79	19	adaptor	adaptor	NOUN
bjos-8668749	79	20	protein	protein	NOUN
bjos-8668749	79	21	(	(	PUNCT
bjos-8668749	79	22	talin	talin	NOUN
bjos-8668749	79	23	)	)	PUNCT
bjos-8668749	79	24	or	or	CCONJ
bjos-8668749	79	25	to	to	ADP
bjos-8668749	79	26	the	the	DET
bjos-8668749	79	27	intermediate	intermediate	ADJ
bjos-8668749	79	28	filaments21	filaments21	NOUN
bjos-8668749	79	29	.	.	PUNCT
bjos-8668749	80	1	in	in	ADP
bjos-8668749	80	2	the	the	DET
bjos-8668749	80	3	extracellular	extracellular	ADJ
bjos-8668749	80	4	space	space	NOUN
bjos-8668749	80	5	,	,	PUNCT
bjos-8668749	80	6	integrins	integrin	VERB
bjos-8668749	80	7	bind	bind	VERB
bjos-8668749	80	8	to	to	ADP
bjos-8668749	80	9	collagen	collagen	NOUN
bjos-8668749	80	10	fibers	fiber	NOUN
bjos-8668749	80	11	,	,	PUNCT
bjos-8668749	80	12	fibronectin	fibronectin	NOUN
bjos-8668749	80	13	,	,	PUNCT
bjos-8668749	80	14	and	and	CCONJ
bjos-8668749	80	15	laminin	laminin	NOUN
bjos-8668749	80	16	.	.	PUNCT
bjos-8668749	81	1	however	however	ADV
bjos-8668749	81	2	,	,	PUNCT
bjos-8668749	81	3	there	there	PRON
bjos-8668749	81	4	are	be	VERB
bjos-8668749	81	5	other	other	ADJ
bjos-8668749	81	6	cells	cell	NOUN
bjos-8668749	81	7	that	that	PRON
bjos-8668749	81	8	possess	possess	VERB
bjos-8668749	81	9	integrins	integrin	NOUN
bjos-8668749	81	10	,	,	PUNCT
bjos-8668749	81	11	such	such	ADJ
bjos-8668749	81	12	as	as	ADP
bjos-8668749	81	13	the	the	DET
bjos-8668749	81	14	white	white	ADJ
bjos-8668749	81	15	blood	blood	NOUN
bjos-8668749	81	16	cells	cell	NOUN
bjos-8668749	81	17	,	,	PUNCT
bjos-8668749	81	18	which	which	PRON
bjos-8668749	81	19	bind	bind	VERB
bjos-8668749	81	20	to	to	ADP
bjos-8668749	81	21	other	other	ADJ
bjos-8668749	81	22	cells	cell	NOUN
bjos-8668749	81	23	that	that	PRON
bjos-8668749	81	24	help	help	VERB
bjos-8668749	81	25	search	search	VERB
bjos-8668749	81	26	for	for	ADP
bjos-8668749	81	27	infections	infection	NOUN
bjos-8668749	81	28	.	.	PUNCT
bjos-8668749	82	1	in	in	ADP
bjos-8668749	82	2	the	the	DET
bjos-8668749	82	3	blood	blood	NOUN
bjos-8668749	82	4	,	,	PUNCT
bjos-8668749	82	5	the	the	DET
bjos-8668749	82	6	binding	binding	NOUN
bjos-8668749	82	7	with	with	ADP
bjos-8668749	82	8	fibrinogen	fibrinogen	NOUN
bjos-8668749	82	9	assists	assist	NOUN
bjos-8668749	82	10	in	in	ADP
bjos-8668749	82	11	clot	clot	NOUN
bjos-8668749	82	12	formation22	formation22	NOUN
bjos-8668749	82	13	.	.	PUNCT
bjos-8668749	83	1	the	the	DET
bjos-8668749	83	2	integrin	integrin	NOUN
bjos-8668749	83	3	structure	structure	NOUN
bjos-8668749	83	4	is	be	AUX
bjos-8668749	83	5	composed	compose	VERB
bjos-8668749	83	6	of	of	ADP
bjos-8668749	83	7	two	two	NUM
bjos-8668749	83	8	heterodimeric	heterodimeric	ADJ
bjos-8668749	83	9	α	α	NOUN
bjos-8668749	83	10	and	and	CCONJ
bjos-8668749	83	11	β	β	NOUN
bjos-8668749	83	12	chains	chain	NOUN
bjos-8668749	83	13	.	.	PUNCT
bjos-8668749	84	1	the	the	DET
bjos-8668749	84	2	α	α	PROPN
bjos-8668749	84	3	part	part	NOUN
bjos-8668749	84	4	contains	contain	VERB
bjos-8668749	84	5	about	about	ADP
bjos-8668749	84	6	1008	1008	NUM
bjos-8668749	84	7	-	-	SYM
bjos-8668749	84	8	1152	1152	NUM
bjos-8668749	84	9	amino	amino	NOUN
bjos-8668749	84	10	acids	acid	NOUN
bjos-8668749	84	11	,	,	PUNCT
bjos-8668749	84	12	with	with	ADP
bjos-8668749	84	13	a	a	DET
bjos-8668749	84	14	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	84	15	region	region	NOUN
bjos-8668749	84	16	of	of	ADP
bjos-8668749	84	17	22	22	NUM
bjos-8668749	84	18	-	-	SYM
bjos-8668749	84	19	32	32	NUM
bjos-8668749	84	20	amino	amino	NOUN
bjos-8668749	84	21	acids	acid	NOUN
bjos-8668749	84	22	and	and	CCONJ
bjos-8668749	84	23	a	a	DET
bjos-8668749	84	24	transmembrane	transmembrane	ADJ
bjos-8668749	84	25	part	part	NOUN
bjos-8668749	84	26	of	of	ADP
bjos-8668749	84	27	20	20	NUM
bjos-8668749	84	28	-	-	SYM
bjos-8668749	84	29	29	29	NUM
bjos-8668749	84	30	amino	amino	NOUN
bjos-8668749	84	31	acids	acid	NOUN
bjos-8668749	84	32	.	.	PUNCT
bjos-8668749	85	1	the	the	DET
bjos-8668749	85	2	β	β	PROPN
bjos-8668749	85	3	part	part	NOUN
bjos-8668749	85	4	consists	consist	VERB
bjos-8668749	85	5	of	of	ADP
bjos-8668749	85	6	770	770	NUM
bjos-8668749	85	7	amino	amino	ADJ
bjos-8668749	85	8	acids	acid	NOUN
bjos-8668749	85	9	with	with	ADP
bjos-8668749	85	10	a	a	DET
bjos-8668749	85	11	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	85	12	region	region	NOUN
bjos-8668749	85	13	of	of	ADP
bjos-8668749	85	14	20	20	NUM
bjos-8668749	85	15	-	-	SYM
bjos-8668749	85	16	50	50	NUM
bjos-8668749	85	17	amino	amino	NOUN
bjos-8668749	85	18	acids	acid	NOUN
bjos-8668749	85	19	and	and	CCONJ
bjos-8668749	85	20	a	a	DET
bjos-8668749	85	21	transmembrane	transmembrane	NOUN
bjos-8668749	85	22	5	5	NUM
bjos-8668749	86	1	nascimento	nascimento	PROPN
bjos-8668749	86	2	et	et	PROPN
bjos-8668749	86	3	al	al	PROPN
bjos-8668749	86	4	.	.	PROPN
bjos-8668749	86	5	braz	braz	PROPN
bjos-8668749	86	6	j	j	PROPN
bjos-8668749	86	7	oral	oral	PROPN
bjos-8668749	86	8	sci	sci	PROPN
bjos-8668749	86	9	.	.	PUNCT
bjos-8668749	87	1	2023;22	2023;22	NUM
bjos-8668749	87	2	:	:	PUNCT
bjos-8668749	87	3	e238749	e238749	PROPN
bjos-8668749	87	4	part	part	NOUN
bjos-8668749	87	5	of	of	ADP
bjos-8668749	87	6	26	26	NUM
bjos-8668749	87	7	-	-	SYM
bjos-8668749	87	8	29	29	NUM
bjos-8668749	87	9	amino	amino	NOUN
bjos-8668749	87	10	acids	acid	NOUN
bjos-8668749	87	11	.	.	PUNCT
bjos-8668749	88	1	the	the	DET
bjos-8668749	88	2	αand	αand	ADJ
bjos-8668749	88	3	β	β	NOUN
bjos-8668749	88	4	-	-	PUNCT
bjos-8668749	88	5	parts	part	NOUN
bjos-8668749	88	6	contain	contain	VERB
bjos-8668749	88	7	disulfide	disulfide	NOUN
bjos-8668749	88	8	bridges	bridge	NOUN
bjos-8668749	88	9	for	for	ADP
bjos-8668749	88	10	protection	protection	NOUN
bjos-8668749	88	11	against	against	ADP
bjos-8668749	88	12	proteolysis	proteolysis	NOUN
bjos-8668749	88	13	(	(	PUNCT
bjos-8668749	88	14	they	they	PRON
bjos-8668749	88	15	do	do	AUX
bjos-8668749	88	16	not	not	PART
bjos-8668749	88	17	covalently	covalently	ADV
bjos-8668749	88	18	bind	bind	VERB
bjos-8668749	88	19	)	)	PUNCT
bjos-8668749	88	20	and	and	CCONJ
bjos-8668749	88	21	bind	bind	VERB
bjos-8668749	88	22	to	to	ADP
bjos-8668749	88	23	the	the	DET
bjos-8668749	88	24	sequence	sequence	NOUN
bjos-8668749	88	25	-	-	PUNCT
bjos-8668749	88	26	specific	specific	ADJ
bjos-8668749	88	27	arginine	arginine	NOUN
bjos-8668749	88	28	-	-	PUNCT
bjos-8668749	88	29	glycine	glycine	NOUN
bjos-8668749	88	30	-	-	PUNCT
bjos-8668749	88	31	aspartic	aspartic	ADJ
bjos-8668749	88	32	acid	acid	NOUN
bjos-8668749	88	33	(	(	PUNCT
bjos-8668749	88	34	rgd	rgd	NOUN
bjos-8668749	88	35	)	)	PUNCT
bjos-8668749	88	36	amino	amino	NOUN
bjos-8668749	88	37	acid	acid	NOUN
bjos-8668749	88	38	sequence	sequence	NOUN
bjos-8668749	88	39	found	find	VERB
bjos-8668749	88	40	in	in	ADP
bjos-8668749	88	41	matrix	matrix	NOUN
bjos-8668749	88	42	proteins	protein	NOUN
bjos-8668749	88	43	such	such	ADJ
bjos-8668749	88	44	as	as	ADP
bjos-8668749	88	45	fibronectin	fibronectin	NOUN
bjos-8668749	88	46	and	and	CCONJ
bjos-8668749	88	47	vitronectin21,22	vitronectin21,22	NOUN
bjos-8668749	88	48	.	.	PUNCT
bjos-8668749	89	1	when	when	SCONJ
bjos-8668749	89	2	integrin	integrin	NOUN
bjos-8668749	89	3	is	be	AUX
bjos-8668749	89	4	in	in	ADP
bjos-8668749	89	5	the	the	DET
bjos-8668749	89	6	inactive	inactive	ADJ
bjos-8668749	89	7	state	state	NOUN
bjos-8668749	89	8	,	,	PUNCT
bjos-8668749	89	9	it	it	PRON
bjos-8668749	89	10	is	be	AUX
bjos-8668749	89	11	in	in	ADP
bjos-8668749	89	12	the	the	DET
bjos-8668749	89	13	folded	fold	VERB
bjos-8668749	89	14	form	form	NOUN
bjos-8668749	89	15	described	describe	VERB
bjos-8668749	89	16	as	as	ADP
bjos-8668749	89	17	jackknife	jackknife	NOUN
bjos-8668749	89	18	-	-	PUNCT
bjos-8668749	89	19	like	like	NOUN
bjos-8668749	89	20	,	,	PUNCT
bjos-8668749	89	21	it	it	PRON
bjos-8668749	89	22	does	do	AUX
bjos-8668749	89	23	not	not	PART
bjos-8668749	89	24	bind	bind	VERB
bjos-8668749	89	25	and	and	CCONJ
bjos-8668749	89	26	does	do	AUX
bjos-8668749	89	27	not	not	PART
bjos-8668749	89	28	signal	signal	VERB
bjos-8668749	89	29	.	.	PUNCT
bjos-8668749	90	1	however	however	ADV
bjos-8668749	90	2	,	,	PUNCT
bjos-8668749	90	3	when	when	SCONJ
bjos-8668749	90	4	activated	activate	VERB
bjos-8668749	90	5	,	,	PUNCT
bjos-8668749	90	6	it	it	PRON
bjos-8668749	90	7	opens	open	VERB
bjos-8668749	90	8	and	and	CCONJ
bjos-8668749	90	9	extends	extend	VERB
bjos-8668749	90	10	away	away	ADV
bjos-8668749	90	11	from	from	ADP
bjos-8668749	90	12	the	the	DET
bjos-8668749	90	13	cell	cell	NOUN
bjos-8668749	90	14	surface	surface	NOUN
bjos-8668749	90	15	.	.	PUNCT
bjos-8668749	91	1	the	the	DET
bjos-8668749	91	2	signaling	signal	VERB
bjos-8668749	91	3	depends	depend	VERB
bjos-8668749	91	4	on	on	ADP
bjos-8668749	91	5	the	the	DET
bjos-8668749	91	6	ligand	ligand	NOUN
bjos-8668749	91	7	and	and	CCONJ
bjos-8668749	91	8	the	the	DET
bjos-8668749	91	9	integrin	integrin	NOUN
bjos-8668749	91	10	.	.	PUNCT
bjos-8668749	92	1	the	the	DET
bjos-8668749	92	2	ligand	ligand	NOUN
bjos-8668749	92	3	affects	affect	VERB
bjos-8668749	92	4	integrin	integrin	NOUN
bjos-8668749	92	5	binding	bind	VERB
bjos-8668749	92	6	and	and	CCONJ
bjos-8668749	92	7	integrin	integrin	NOUN
bjos-8668749	92	8	clustering	cluster	VERB
bjos-8668749	92	9	and	and	CCONJ
bjos-8668749	92	10	works	work	VERB
bjos-8668749	92	11	in	in	ADP
bjos-8668749	92	12	both	both	DET
bjos-8668749	92	13	directions	direction	NOUN
bjos-8668749	92	14	.	.	PUNCT
bjos-8668749	93	1	when	when	SCONJ
bjos-8668749	93	2	a	a	DET
bjos-8668749	93	3	ligand	ligand	NOUN
bjos-8668749	93	4	adheres	adhere	VERB
bjos-8668749	93	5	to	to	ADP
bjos-8668749	93	6	a	a	DET
bjos-8668749	93	7	target	target	NOUN
bjos-8668749	93	8	,	,	PUNCT
bjos-8668749	93	9	it	it	PRON
bjos-8668749	93	10	sends	send	VERB
bjos-8668749	93	11	signals	signal	NOUN
bjos-8668749	93	12	for	for	SCONJ
bjos-8668749	93	13	the	the	DET
bjos-8668749	93	14	cell	cell	NOUN
bjos-8668749	93	15	to	to	PART
bjos-8668749	93	16	undergo	undergo	VERB
bjos-8668749	93	17	changes	change	NOUN
bjos-8668749	93	18	,	,	PUNCT
bjos-8668749	93	19	such	such	ADJ
bjos-8668749	93	20	as	as	ADP
bjos-8668749	93	21	controlling	control	VERB
bjos-8668749	93	22	its	its	PRON
bjos-8668749	93	23	growth	growth	NOUN
bjos-8668749	93	24	and	and	CCONJ
bjos-8668749	93	25	shape23,24	shape23,24	NOUN
bjos-8668749	93	26	.	.	PUNCT
bjos-8668749	94	1	figure	figure	NOUN
bjos-8668749	94	2	1	1	NUM
bjos-8668749	94	3	shows	show	VERB
bjos-8668749	94	4	schematically	schematically	NOUN
bjos-8668749	94	5	the	the	DET
bjos-8668749	94	6	integrin	integrin	NOUN
bjos-8668749	94	7	binding	bind	VERB
bjos-8668749	94	8	to	to	ADP
bjos-8668749	94	9	its	its	PRON
bjos-8668749	94	10	intracellular	intracellular	ADJ
bjos-8668749	94	11	receptor	receptor	NOUN
bjos-8668749	94	12	.	.	PUNCT
bjos-8668749	95	1	legend	legend	NOUN
bjos-8668749	95	2	:	:	PUNCT
bjos-8668749	95	3	representation	representation	NOUN
bjos-8668749	95	4	of	of	ADP
bjos-8668749	95	5	the	the	DET
bjos-8668749	95	6	integrin	integrin	NOUN
bjos-8668749	95	7	.	.	PUNCT
bjos-8668749	96	1	on	on	ADP
bjos-8668749	96	2	the	the	DET
bjos-8668749	96	3	left	left	ADJ
bjos-8668749	96	4	side	side	NOUN
bjos-8668749	96	5	the	the	DET
bjos-8668749	96	6	inactivated	inactivated	ADJ
bjos-8668749	96	7	integrin	integrin	NOUN
bjos-8668749	96	8	,	,	PUNCT
bjos-8668749	96	9	while	while	SCONJ
bjos-8668749	96	10	on	on	ADP
bjos-8668749	96	11	the	the	DET
bjos-8668749	96	12	right	right	ADJ
bjos-8668749	96	13	side	side	NOUN
bjos-8668749	96	14	the	the	DET
bjos-8668749	96	15	activated	activate	VERB
bjos-8668749	96	16	protein	protein	NOUN
bjos-8668749	96	17	.	.	PUNCT
bjos-8668749	97	1	adapted	adapt	VERB
bjos-8668749	97	2	from	from	ADP
bjos-8668749	97	3	biorender	biorender	NOUN
bjos-8668749	97	4	(	(	PUNCT
bjos-8668749	97	5	2022	2022	NUM
bjos-8668749	97	6	)	)	PUNCT
bjos-8668749	97	7	.	.	PUNCT
bjos-8668749	98	1	figure	figure	NOUN
bjos-8668749	98	2	1	1	NUM
bjos-8668749	98	3	.	.	PUNCT
bjos-8668749	99	1	integrin	integrin	PROPN
bjos-8668749	99	2	structure	structure	PROPN
bjos-8668749	99	3	schematic	schematic	ADJ
bjos-8668749	99	4	integrin	integrin	NOUN
bjos-8668749	99	5	performs	perform	VERB
bjos-8668749	99	6	bidirectional	bidirectional	ADJ
bjos-8668749	99	7	signaling	signaling	NOUN
bjos-8668749	99	8	:	:	PUNCT
bjos-8668749	99	9	inside	inside	ADV
bjos-8668749	99	10	-	-	PUNCT
bjos-8668749	99	11	out	out	NOUN
bjos-8668749	99	12	and	and	CCONJ
bjos-8668749	99	13	outside	outside	NOUN
bjos-8668749	99	14	-	-	PUNCT
bjos-8668749	99	15	in	in	NOUN
bjos-8668749	99	16	.	.	PUNCT
bjos-8668749	100	1	the	the	DET
bjos-8668749	100	2	first	first	ADJ
bjos-8668749	100	3	is	be	AUX
bjos-8668749	100	4	configured	configure	VERB
bjos-8668749	100	5	with	with	ADP
bjos-8668749	100	6	the	the	DET
bjos-8668749	100	7	cellular	cellular	ADJ
bjos-8668749	100	8	processes	process	NOUN
bjos-8668749	100	9	/	/	SYM
bjos-8668749	100	10	mechanisms	mechanism	NOUN
bjos-8668749	100	11	that	that	PRON
bjos-8668749	100	12	promote	promote	VERB
bjos-8668749	100	13	the	the	DET
bjos-8668749	100	14	change	change	NOUN
bjos-8668749	100	15	in	in	ADP
bjos-8668749	100	16	affinity	affinity	NOUN
bjos-8668749	100	17	for	for	ADP
bjos-8668749	100	18	ligands	ligand	NOUN
bjos-8668749	100	19	.	.	PUNCT
bjos-8668749	101	1	while	while	SCONJ
bjos-8668749	101	2	the	the	DET
bjos-8668749	101	3	second	second	NOUN
bjos-8668749	101	4	initiates	initiate	VERB
bjos-8668749	101	5	a	a	DET
bjos-8668749	101	6	signals	signal	NOUN
bjos-8668749	101	7	cascade	cascade	NOUN
bjos-8668749	101	8	to	to	PART
bjos-8668749	101	9	modulate	modulate	VERB
bjos-8668749	101	10	cell	cell	NOUN
bjos-8668749	101	11	behavior	behavior	NOUN
bjos-8668749	101	12	.	.	PUNCT
bjos-8668749	102	1	thus	thus	ADV
bjos-8668749	102	2	,	,	PUNCT
bjos-8668749	102	3	integrins	integrin	NOUN
bjos-8668749	102	4	provide	provide	VERB
bjos-8668749	102	5	anchoring	anchoring	NOUN
bjos-8668749	102	6	and	and	CCONJ
bjos-8668749	102	7	signaling	signal	VERB
bjos-8668749	102	8	in	in	ADP
bjos-8668749	102	9	the	the	DET
bjos-8668749	102	10	development	development	NOUN
bjos-8668749	102	11	,	,	PUNCT
bjos-8668749	102	12	organization	organization	NOUN
bjos-8668749	102	13	,	,	PUNCT
bjos-8668749	102	14	maintenance	maintenance	NOUN
bjos-8668749	102	15	,	,	PUNCT
bjos-8668749	102	16	and	and	CCONJ
bjos-8668749	102	17	repair	repair	NOUN
bjos-8668749	102	18	of	of	ADP
bjos-8668749	102	19	various	various	ADJ
bjos-8668749	102	20	tissues	tissue	NOUN
bjos-8668749	102	21	.	.	PUNCT
bjos-8668749	103	1	they	they	PRON
bjos-8668749	103	2	act	act	VERB
bjos-8668749	103	3	in	in	ADP
bjos-8668749	103	4	the	the	DET
bjos-8668749	103	5	processes	process	NOUN
bjos-8668749	103	6	of	of	ADP
bjos-8668749	103	7	survival	survival	NOUN
bjos-8668749	103	8	,	,	PUNCT
bjos-8668749	103	9	migration	migration	NOUN
bjos-8668749	103	10	,	,	PUNCT
bjos-8668749	103	11	and	and	CCONJ
bjos-8668749	103	12	cell	cell	NOUN
bjos-8668749	103	13	cycle	cycle	NOUN
bjos-8668749	103	14	progression	progression	NOUN
bjos-8668749	103	15	,	,	PUNCT
bjos-8668749	103	16	as	as	ADV
bjos-8668749	103	17	well	well	ADV
bjos-8668749	103	18	as	as	ADP
bjos-8668749	103	19	in	in	ADP
bjos-8668749	103	20	the	the	DET
bjos-8668749	103	21	expression	expression	NOUN
bjos-8668749	103	22	of	of	ADP
bjos-8668749	103	23	differentiated	differentiated	ADJ
bjos-8668749	103	24	phenotypes	phenotype	NOUN
bjos-8668749	103	25	.	.	PUNCT
bjos-8668749	104	1	in	in	ADP
bjos-8668749	104	2	other	other	ADJ
bjos-8668749	104	3	words	word	NOUN
bjos-8668749	104	4	,	,	PUNCT
bjos-8668749	104	5	they	they	PRON
bjos-8668749	104	6	act	act	VERB
bjos-8668749	104	7	as	as	ADP
bjos-8668749	104	8	regulators	regulator	NOUN
bjos-8668749	104	9	of	of	ADP
bjos-8668749	104	10	cellular	cellular	ADJ
bjos-8668749	104	11	response	response	NOUN
bjos-8668749	104	12	to	to	ADP
bjos-8668749	104	13	implanted	implant	VERB
bjos-8668749	104	14	devices	device	NOUN
bjos-8668749	104	15	and	and	CCONJ
bjos-8668749	104	16	biomaterial	biomaterial	ADJ
bjos-8668749	104	17	biological	biological	ADJ
bjos-8668749	104	18	interaction25	interaction25	NOUN
bjos-8668749	104	19	.	.	PUNCT
bjos-8668749	105	1	6	6	NUM
bjos-8668749	105	2	nascimento	nascimento	PROPN
bjos-8668749	105	3	et	et	PROPN
bjos-8668749	105	4	al	al	PROPN
bjos-8668749	105	5	.	.	PROPN
bjos-8668749	106	1	braz	braz	PROPN
bjos-8668749	106	2	j	j	PROPN
bjos-8668749	106	3	oral	oral	PROPN
bjos-8668749	106	4	sci	sci	PROPN
bjos-8668749	106	5	.	.	PUNCT
bjos-8668749	107	1	2023;22	2023;22	NUM
bjos-8668749	107	2	:	:	PUNCT
bjos-8668749	107	3	e238749	e238749	NUM
bjos-8668749	107	4	bone	bone	NOUN
bjos-8668749	107	5	tissue	tissue	NOUN
bjos-8668749	107	6	cells	cell	NOUN
bjos-8668749	107	7	,	,	PUNCT
bjos-8668749	107	8	especially	especially	ADV
bjos-8668749	107	9	,	,	PUNCT
bjos-8668749	107	10	osteoblasts	osteoblast	NOUN
bjos-8668749	107	11	,	,	PUNCT
bjos-8668749	107	12	express	express	VERB
bjos-8668749	107	13	a	a	DET
bjos-8668749	107	14	range	range	NOUN
bjos-8668749	107	15	of	of	ADP
bjos-8668749	107	16	integrins	integrin	NOUN
bjos-8668749	107	17	,	,	PUNCT
bjos-8668749	107	18	usually	usually	ADV
bjos-8668749	107	19	the	the	DET
bjos-8668749	107	20	integrin	integrin	NOUN
bjos-8668749	107	21	subunits	subunit	VERB
bjos-8668749	107	22	α1	α1	PROPN
bjos-8668749	107	23	,	,	PUNCT
bjos-8668749	107	24	α2	α2	ADJ
bjos-8668749	107	25	,	,	PUNCT
bjos-8668749	107	26	α3	α3	NOUN
bjos-8668749	107	27	,	,	PUNCT
bjos-8668749	107	28	α4	α4	NOUN
bjos-8668749	107	29	,	,	PUNCT
bjos-8668749	107	30	α5	α5	NOUN
bjos-8668749	107	31	,	,	PUNCT
bjos-8668749	107	32	α6	α6	NOUN
bjos-8668749	107	33	,	,	PUNCT
bjos-8668749	107	34	αv	αv	NOUN
bjos-8668749	107	35	,	,	PUNCT
bjos-8668749	107	36	β1	β1	NOUN
bjos-8668749	107	37	,	,	PUNCT
bjos-8668749	107	38	β3	β3	ADJ
bjos-8668749	107	39	and	and	CCONJ
bjos-8668749	107	40	β5	β5	ADJ
bjos-8668749	107	41	.	.	PUNCT
bjos-8668749	108	1	this	this	DET
bjos-8668749	108	2	expression	expression	NOUN
bjos-8668749	108	3	is	be	AUX
bjos-8668749	108	4	not	not	PART
bjos-8668749	108	5	constant	constant	ADJ
bjos-8668749	108	6	,	,	PUNCT
bjos-8668749	108	7	i.e.	i.e.	X
bjos-8668749	108	8	,	,	PUNCT
bjos-8668749	108	9	it	it	PRON
bjos-8668749	108	10	varies	vary	VERB
bjos-8668749	108	11	with	with	ADP
bjos-8668749	108	12	the	the	DET
bjos-8668749	108	13	stage	stage	NOUN
bjos-8668749	108	14	of	of	ADP
bjos-8668749	108	15	osteoblast	osteoblast	ADJ
bjos-8668749	108	16	development26,27	development26,27	NUM
bjos-8668749	108	17	.	.	PUNCT
bjos-8668749	109	1	cell	cell	NOUN
bjos-8668749	109	2	behavior	behavior	NOUN
bjos-8668749	109	3	changes	change	NOUN
bjos-8668749	109	4	following	follow	VERB
bjos-8668749	109	5	integrin	integrin	NOUN
bjos-8668749	109	6	-	-	PUNCT
bjos-8668749	109	7	signaled	signal	VERB
bjos-8668749	109	8	cell	cell	NOUN
bjos-8668749	109	9	adhesion	adhesion	NOUN
bjos-8668749	109	10	.	.	PUNCT
bjos-8668749	110	1	this	this	DET
bjos-8668749	110	2	signaling	signal	VERB
bjos-8668749	110	3	can	can	AUX
bjos-8668749	110	4	be	be	AUX
bjos-8668749	110	5	from	from	ADP
bjos-8668749	110	6	the	the	DET
bjos-8668749	110	7	outside	outside	NOUN
bjos-8668749	110	8	in	in	ADP
bjos-8668749	110	9	(	(	PUNCT
bjos-8668749	110	10	signal	signal	ADJ
bjos-8668749	110	11	transduction	transduction	NOUN
bjos-8668749	110	12	from	from	ADP
bjos-8668749	110	13	the	the	DET
bjos-8668749	110	14	matrix	matrix	NOUN
bjos-8668749	110	15	to	to	ADP
bjos-8668749	110	16	the	the	DET
bjos-8668749	110	17	cell	cell	NOUN
bjos-8668749	110	18	)	)	PUNCT
bjos-8668749	110	19	and	and	CCONJ
bjos-8668749	110	20	from	from	ADP
bjos-8668749	110	21	the	the	DET
bjos-8668749	110	22	inside	inside	NOUN
bjos-8668749	110	23	out	out	ADP
bjos-8668749	110	24	(	(	PUNCT
bjos-8668749	110	25	cell	cell	NOUN
bjos-8668749	110	26	binding	bind	VERB
bjos-8668749	110	27	to	to	ADP
bjos-8668749	110	28	the	the	DET
bjos-8668749	110	29	matrix	matrix	NOUN
bjos-8668749	110	30	)	)	PUNCT
bjos-8668749	110	31	.	.	PUNCT
bjos-8668749	111	1	depending	depend	VERB
bjos-8668749	111	2	on	on	ADP
bjos-8668749	111	3	the	the	DET
bjos-8668749	111	4	type	type	NOUN
bjos-8668749	111	5	of	of	ADP
bjos-8668749	111	6	signaling	signal	VERB
bjos-8668749	111	7	,	,	PUNCT
bjos-8668749	111	8	the	the	DET
bjos-8668749	111	9	cell	cell	NOUN
bjos-8668749	111	10	moves	move	VERB
bjos-8668749	111	11	,	,	PUNCT
bjos-8668749	111	12	grows	grow	VERB
bjos-8668749	111	13	,	,	PUNCT
bjos-8668749	111	14	proliferates	proliferate	NOUN
bjos-8668749	111	15	,	,	PUNCT
bjos-8668749	111	16	and	and	CCONJ
bjos-8668749	111	17	undergoes	undergoes	PROPN
bjos-8668749	111	18	differentiation25	differentiation25	PROPN
bjos-8668749	111	19	.	.	PUNCT
bjos-8668749	112	1	specifically	specifically	ADV
bjos-8668749	112	2	,	,	PUNCT
bjos-8668749	112	3	in	in	ADP
bjos-8668749	112	4	the	the	DET
bjos-8668749	112	5	presence	presence	NOUN
bjos-8668749	112	6	of	of	ADP
bjos-8668749	112	7	titanium	titanium	NOUN
bjos-8668749	112	8	alloys	alloy	NOUN
bjos-8668749	112	9	,	,	PUNCT
bjos-8668749	112	10	osteoblasts	osteoblast	NOUN
bjos-8668749	112	11	express	express	VERB
bjos-8668749	112	12	the	the	DET
bjos-8668749	112	13	integrin	integrin	NOUN
bjos-8668749	112	14	subunits	subunit	NOUN
bjos-8668749	112	15	α2	α2	PROPN
bjos-8668749	112	16	,	,	PUNCT
bjos-8668749	112	17	α3	α3	NOUN
bjos-8668749	112	18	,	,	PUNCT
bjos-8668749	112	19	α4	α4	NOUN
bjos-8668749	112	20	,	,	PUNCT
bjos-8668749	112	21	α6	α6	NOUN
bjos-8668749	112	22	,	,	PUNCT
bjos-8668749	112	23	αv	αv	ADP
bjos-8668749	112	24	,	,	PUNCT
bjos-8668749	112	25	β1	β1	NOUN
bjos-8668749	112	26	,	,	PUNCT
bjos-8668749	112	27	and	and	CCONJ
bjos-8668749	112	28	β327	β327	PROPN
bjos-8668749	112	29	.	.	PUNCT
bjos-8668749	113	1	β1	β1	PROPN
bjos-8668749	113	2	integrin	integrin	PROPN
bjos-8668749	113	3	(	(	PUNCT
bjos-8668749	113	4	itgb1	itgb1	PROPN
bjos-8668749	113	5	)	)	PUNCT
bjos-8668749	113	6	is	be	AUX
bjos-8668749	113	7	a	a	DET
bjos-8668749	113	8	cell	cell	NOUN
bjos-8668749	113	9	surface	surface	NOUN
bjos-8668749	113	10	receptor	receptor	NOUN
bjos-8668749	113	11	that	that	PRON
bjos-8668749	113	12	in	in	ADP
bjos-8668749	113	13	humans	human	NOUN
bjos-8668749	113	14	is	be	AUX
bjos-8668749	113	15	encoded	encode	VERB
bjos-8668749	113	16	by	by	ADP
bjos-8668749	113	17	the	the	DET
bjos-8668749	113	18	itgb1	itgb1	NOUN
bjos-8668749	113	19	gene	gene	NOUN
bjos-8668749	113	20	.	.	PUNCT
bjos-8668749	114	1	this	this	DET
bjos-8668749	114	2	integrin	integrin	NOUN
bjos-8668749	114	3	associates	associate	VERB
bjos-8668749	114	4	with	with	ADP
bjos-8668749	114	5	α1	α1	PROPN
bjos-8668749	114	6	integrin	integrin	NOUN
bjos-8668749	114	7	and	and	CCONJ
bjos-8668749	114	8	α2	α2	ADJ
bjos-8668749	114	9	integrin	integrin	NOUN
bjos-8668749	114	10	to	to	PART
bjos-8668749	114	11	form	form	VERB
bjos-8668749	114	12	integrin	integrin	NOUN
bjos-8668749	114	13	complexes	complex	NOUN
bjos-8668749	114	14	that	that	PRON
bjos-8668749	114	15	function	function	VERB
bjos-8668749	114	16	as	as	ADP
bjos-8668749	114	17	collagen	collagen	NOUN
bjos-8668749	114	18	receptors	receptor	NOUN
bjos-8668749	114	19	.	.	PUNCT
bjos-8668749	115	1	it	it	PRON
bjos-8668749	115	2	also	also	ADV
bjos-8668749	115	3	forms	form	VERB
bjos-8668749	115	4	dimers	dimer	NOUN
bjos-8668749	115	5	with	with	ADP
bjos-8668749	115	6	α3	α3	ADJ
bjos-8668749	115	7	integrin	integrin	NOUN
bjos-8668749	115	8	to	to	PART
bjos-8668749	115	9	form	form	VERB
bjos-8668749	115	10	integrin	integrin	NOUN
bjos-8668749	115	11	receptors	receptor	NOUN
bjos-8668749	115	12	for	for	ADP
bjos-8668749	115	13	netrin	netrin	NOUN
bjos-8668749	115	14	1	1	NUM
bjos-8668749	115	15	and	and	CCONJ
bjos-8668749	115	16	reelin	reelin	NOUN
bjos-8668749	115	17	.	.	PUNCT
bjos-8668749	116	1	these	these	PRON
bjos-8668749	116	2	and	and	CCONJ
bjos-8668749	116	3	other	other	ADJ
bjos-8668749	116	4	β1	β1	PROPN
bjos-8668749	116	5	integrin	integrin	NOUN
bjos-8668749	116	6	complexes	complex	NOUN
bjos-8668749	116	7	are	be	AUX
bjos-8668749	116	8	historically	historically	ADV
bjos-8668749	116	9	known	know	VERB
bjos-8668749	116	10	as	as	ADP
bjos-8668749	116	11	very	very	ADV
bjos-8668749	116	12	late	late	ADJ
bjos-8668749	116	13	activation	activation	NOUN
bjos-8668749	116	14	antigens28	antigens28	PROPN
bjos-8668749	116	15	.	.	PUNCT
bjos-8668749	117	1	integrin	integrin	NOUN
bjos-8668749	117	2	receptors	receptor	NOUN
bjos-8668749	117	3	exist	exist	VERB
bjos-8668749	117	4	as	as	SCONJ
bjos-8668749	117	5	heterodimers	heterodimer	NOUN
bjos-8668749	117	6	and	and	CCONJ
bjos-8668749	117	7	more	more	ADJ
bjos-8668749	117	8	than	than	ADP
bjos-8668749	117	9	20	20	NUM
bjos-8668749	117	10	different	different	ADJ
bjos-8668749	117	11	heterodimeric	heterodimeric	ADJ
bjos-8668749	117	12	integrin	integrin	NOUN
bjos-8668749	117	13	receptors	receptor	NOUN
bjos-8668749	117	14	have	have	AUX
bjos-8668749	117	15	been	be	AUX
bjos-8668749	117	16	described	describe	VERB
bjos-8668749	117	17	.	.	PUNCT
bjos-8668749	118	1	all	all	DET
bjos-8668749	118	2	integrins	integrin	NOUN
bjos-8668749	118	3	,	,	PUNCT
bjos-8668749	118	4	α	α	NOUN
bjos-8668749	118	5	and	and	CCONJ
bjos-8668749	118	6	β	β	NOUN
bjos-8668749	118	7	forms	form	NOUN
bjos-8668749	118	8	,	,	PUNCT
bjos-8668749	118	9	have	have	VERB
bjos-8668749	118	10	large	large	ADJ
bjos-8668749	118	11	extracellular	extracellular	ADJ
bjos-8668749	118	12	and	and	CCONJ
bjos-8668749	118	13	short	short	ADJ
bjos-8668749	118	14	intracellular	intracellular	ADJ
bjos-8668749	118	15	domains26	domains26	NOUN
bjos-8668749	118	16	.	.	PUNCT
bjos-8668749	119	1	the	the	DET
bjos-8668749	119	2	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	119	3	domain	domain	NOUN
bjos-8668749	119	4	of	of	ADP
bjos-8668749	119	5	β1	β1	PROPN
bjos-8668749	119	6	integrin	integrin	NOUN
bjos-8668749	119	7	binds	bind	VERB
bjos-8668749	119	8	to	to	ADP
bjos-8668749	119	9	the	the	DET
bjos-8668749	119	10	actin	actin	NOUN
bjos-8668749	119	11	cytoskeleton	cytoskeleton	PROPN
bjos-8668749	119	12	.	.	PUNCT
bjos-8668749	120	1	β1	β1	PROPN
bjos-8668749	120	2	integrin	integrin	PROPN
bjos-8668749	120	3	is	be	AUX
bjos-8668749	120	4	the	the	PRON
bjos-8668749	120	5	most	most	ADV
bjos-8668749	120	6	abundantly	abundantly	ADV
bjos-8668749	120	7	expressed	express	VERB
bjos-8668749	120	8	β	β	NOUN
bjos-8668749	120	9	-	-	NOUN
bjos-8668749	120	10	integrin	integrin	NOUN
bjos-8668749	120	11	and	and	CCONJ
bjos-8668749	120	12	associates	associate	NOUN
bjos-8668749	120	13	with	with	ADP
bjos-8668749	120	14	at	at	ADV
bjos-8668749	120	15	least	least	ADV
bjos-8668749	120	16	10	10	NUM
bjos-8668749	120	17	different	different	ADJ
bjos-8668749	120	18	α	α	PROPN
bjos-8668749	120	19	integrin	integrin	NOUN
bjos-8668749	120	20	subunits27	subunits27	NOUN
bjos-8668749	120	21	.	.	PUNCT
bjos-8668749	121	1	integrin	integrin	PROPN
bjos-8668749	121	2	family	family	NOUN
bjos-8668749	121	3	members	member	NOUN
bjos-8668749	121	4	are	be	AUX
bjos-8668749	121	5	membrane	membrane	NOUN
bjos-8668749	121	6	receptors	receptor	NOUN
bjos-8668749	121	7	involved	involve	VERB
bjos-8668749	121	8	in	in	ADP
bjos-8668749	121	9	cell	cell	NOUN
bjos-8668749	121	10	adhesion	adhesion	NOUN
bjos-8668749	121	11	and	and	CCONJ
bjos-8668749	121	12	recognition	recognition	NOUN
bjos-8668749	121	13	in	in	ADP
bjos-8668749	121	14	a	a	DET
bjos-8668749	121	15	variety	variety	NOUN
bjos-8668749	121	16	of	of	ADP
bjos-8668749	121	17	processes	process	NOUN
bjos-8668749	121	18	,	,	PUNCT
bjos-8668749	121	19	including	include	VERB
bjos-8668749	121	20	embryogenesis	embryogenesis	NOUN
bjos-8668749	121	21	,	,	PUNCT
bjos-8668749	121	22	hemostasis	hemostasis	NOUN
bjos-8668749	121	23	,	,	PUNCT
bjos-8668749	121	24	tissue	tissue	NOUN
bjos-8668749	121	25	repair	repair	NOUN
bjos-8668749	121	26	,	,	PUNCT
bjos-8668749	121	27	immune	immune	ADJ
bjos-8668749	121	28	response	response	NOUN
bjos-8668749	121	29	,	,	PUNCT
bjos-8668749	121	30	and	and	CCONJ
bjos-8668749	121	31	metastatic	metastatic	ADJ
bjos-8668749	121	32	spread	spread	NOUN
bjos-8668749	121	33	of	of	ADP
bjos-8668749	121	34	tumor	tumor	NOUN
bjos-8668749	121	35	cells25,26	cells25,26	NOUN
bjos-8668749	121	36	.	.	PUNCT
bjos-8668749	122	1	integrins	integrin	NOUN
bjos-8668749	122	2	bind	bind	VERB
bjos-8668749	122	3	the	the	DET
bjos-8668749	122	4	actin	actin	NOUN
bjos-8668749	122	5	cytoskeleton	cytoskeleton	PROPN
bjos-8668749	122	6	to	to	ADP
bjos-8668749	122	7	the	the	DET
bjos-8668749	122	8	extracellular	extracellular	ADJ
bjos-8668749	122	9	matrix	matrix	NOUN
bjos-8668749	122	10	and	and	CCONJ
bjos-8668749	122	11	transmit	transmit	VERB
bjos-8668749	122	12	bidirectional	bidirectional	ADJ
bjos-8668749	122	13	signals	signal	NOUN
bjos-8668749	122	14	between	between	ADP
bjos-8668749	122	15	the	the	DET
bjos-8668749	122	16	extracellular	extracellular	ADJ
bjos-8668749	122	17	matrix	matrix	NOUN
bjos-8668749	122	18	and	and	CCONJ
bjos-8668749	122	19	the	the	DET
bjos-8668749	122	20	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	122	21	domains	domain	NOUN
bjos-8668749	122	22	.	.	PUNCT
bjos-8668749	123	1	the	the	DET
bjos-8668749	123	2	β	β	NOUN
bjos-8668749	123	3	-	-	NOUN
bjos-8668749	123	4	integrins	integrin	NOUN
bjos-8668749	123	5	are	be	AUX
bjos-8668749	123	6	primarily	primarily	ADV
bjos-8668749	123	7	responsible	responsible	ADJ
bjos-8668749	123	8	for	for	ADP
bjos-8668749	123	9	directing	direct	VERB
bjos-8668749	123	10	integrin	integrin	NOUN
bjos-8668749	123	11	dimers	dimer	NOUN
bjos-8668749	123	12	to	to	ADP
bjos-8668749	123	13	the	the	DET
bjos-8668749	123	14	appropriate	appropriate	ADJ
bjos-8668749	123	15	subcellular	subcellular	ADJ
bjos-8668749	123	16	sites	site	NOUN
bjos-8668749	123	17	,	,	PUNCT
bjos-8668749	123	18	which	which	PRON
bjos-8668749	123	19	in	in	ADP
bjos-8668749	123	20	adhesive	adhesive	ADJ
bjos-8668749	123	21	cells	cell	NOUN
bjos-8668749	123	22	are	be	AUX
bjos-8668749	123	23	mainly	mainly	ADV
bjos-8668749	123	24	focal	focal	ADJ
bjos-8668749	123	25	adhesions	adhesion	NOUN
bjos-8668749	123	26	.	.	PUNCT
bjos-8668749	124	1	β1	β1	PROPN
bjos-8668749	124	2	integrin	integrin	PROPN
bjos-8668749	124	3	mutants	mutant	NOUN
bjos-8668749	124	4	lose	lose	VERB
bjos-8668749	124	5	the	the	DET
bjos-8668749	124	6	ability	ability	NOUN
bjos-8668749	124	7	to	to	PART
bjos-8668749	124	8	target	target	VERB
bjos-8668749	124	9	to	to	ADP
bjos-8668749	124	10	focal	focal	ADJ
bjos-8668749	124	11	adhesion	adhesion	NOUN
bjos-8668749	124	12	sites28	sites28	NOUN
bjos-8668749	124	13	.	.	PUNCT
bjos-8668749	125	1	three	three	NUM
bjos-8668749	125	2	isoforms	isoform	NOUN
bjos-8668749	125	3	of	of	ADP
bjos-8668749	125	4	β1	β1	PROPN
bjos-8668749	125	5	integrin	integrin	NOUN
bjos-8668749	125	6	have	have	AUX
bjos-8668749	125	7	been	be	AUX
bjos-8668749	125	8	identified	identify	VERB
bjos-8668749	125	9	,	,	PUNCT
bjos-8668749	125	10	named	name	VERB
bjos-8668749	125	11	β1b	β1b	PROPN
bjos-8668749	125	12	,	,	PUNCT
bjos-8668749	125	13	β1c	β1c	PROPN
bjos-8668749	125	14	and	and	CCONJ
bjos-8668749	125	15	β1d	β1d	PROPN
bjos-8668749	125	16	.	.	PUNCT
bjos-8668749	125	17	β1b	β1b	PROPN
bjos-8668749	126	1	integrin	integrin	PROPN
bjos-8668749	126	2	is	be	AUX
bjos-8668749	126	3	transcribed	transcribe	VERB
bjos-8668749	126	4	when	when	SCONJ
bjos-8668749	126	5	the	the	DET
bjos-8668749	126	6	proximal	proximal	ADJ
bjos-8668749	126	7	26	26	NUM
bjos-8668749	126	8	amino	amino	NOUN
bjos-8668749	126	9	acids	acid	NOUN
bjos-8668749	126	10	of	of	ADP
bjos-8668749	126	11	the	the	DET
bjos-8668749	126	12	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	126	13	domain	domain	NOUN
bjos-8668749	126	14	in	in	ADP
bjos-8668749	126	15	exon	exon	NOUN
bjos-8668749	126	16	6	6	NUM
bjos-8668749	126	17	are	be	AUX
bjos-8668749	126	18	retained	retain	VERB
bjos-8668749	126	19	and	and	CCONJ
bjos-8668749	126	20	then	then	ADV
bjos-8668749	126	21	succeeded	succeed	VERB
bjos-8668749	126	22	by	by	ADP
bjos-8668749	126	23	a	a	DET
bjos-8668749	126	24	12	12	NUM
bjos-8668749	126	25	amino	amino	NOUN
bjos-8668749	126	26	acid	acid	NOUN
bjos-8668749	126	27	stretch	stretch	NOUN
bjos-8668749	126	28	from	from	ADP
bjos-8668749	126	29	an	an	DET
bjos-8668749	126	30	adjacent	adjacent	ADJ
bjos-8668749	126	31	intronic	intronic	ADJ
bjos-8668749	126	32	region	region	NOUN
bjos-8668749	126	33	.	.	PUNCT
bjos-8668749	127	1	the	the	DET
bjos-8668749	127	2	β1b	β1b	PROPN
bjos-8668749	127	3	integrin	integrin	PROPN
bjos-8668749	127	4	isoform	isoform	NOUN
bjos-8668749	127	5	acts	act	VERB
bjos-8668749	127	6	as	as	ADP
bjos-8668749	127	7	a	a	DET
bjos-8668749	127	8	dominant	dominant	ADJ
bjos-8668749	127	9	negative	negative	NOUN
bjos-8668749	127	10	in	in	ADP
bjos-8668749	127	11	that	that	SCONJ
bjos-8668749	127	12	it	it	PRON
bjos-8668749	127	13	inhibits	inhibit	VERB
bjos-8668749	127	14	cell	cell	NOUN
bjos-8668749	127	15	adhesion26,28	adhesion26,28	PROPN
bjos-8668749	127	16	.	.	PUNCT
bjos-8668749	128	1	the	the	DET
bjos-8668749	128	2	second	second	ADJ
bjos-8668749	128	3	β1	β1	PROPN
bjos-8668749	128	4	integrin	integrin	NOUN
bjos-8668749	128	5	isoform	isoform	NOUN
bjos-8668749	128	6	,	,	PUNCT
bjos-8668749	128	7	called	call	VERB
bjos-8668749	128	8	β1c	β1c	PROPN
bjos-8668749	128	9	,	,	PUNCT
bjos-8668749	128	10	is	be	AUX
bjos-8668749	128	11	described	describe	VERB
bjos-8668749	128	12	as	as	ADP
bjos-8668749	128	13	having	have	VERB
bjos-8668749	128	14	48	48	NUM
bjos-8668749	128	15	additional	additional	ADJ
bjos-8668749	128	16	amino	amino	ADJ
bjos-8668749	128	17	acids	acid	NOUN
bjos-8668749	128	18	attached	attach	VERB
bjos-8668749	128	19	to	to	ADP
bjos-8668749	128	20	the	the	DET
bjos-8668749	128	21	26	26	NUM
bjos-8668749	128	22	amino	amino	NOUN
bjos-8668749	128	23	acids	acid	NOUN
bjos-8668749	128	24	in	in	ADP
bjos-8668749	128	25	the	the	DET
bjos-8668749	128	26	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	128	27	domain	domain	NOUN
bjos-8668749	128	28	.	.	PUNCT
bjos-8668749	129	1	this	this	DET
bjos-8668749	129	2	isoform	isoform	NOUN
bjos-8668749	129	3	integrin	integrin	NOUN
bjos-8668749	129	4	function	function	NOUN
bjos-8668749	129	5	is	be	AUX
bjos-8668749	129	6	inhibitory	inhibitory	ADJ
bjos-8668749	129	7	on	on	ADP
bjos-8668749	129	8	dna	dna	ADJ
bjos-8668749	129	9	synthesis	synthesis	NOUN
bjos-8668749	129	10	in	in	ADP
bjos-8668749	129	11	phase	phase	NOUN
bjos-8668749	129	12	g1	g1	NOUN
bjos-8668749	129	13	of	of	ADP
bjos-8668749	129	14	the	the	DET
bjos-8668749	129	15	cell	cell	NOUN
bjos-8668749	129	16	cycle	cycle	NOUN
bjos-8668749	129	17	.	.	PUNCT
bjos-8668749	130	1	the	the	DET
bjos-8668749	130	2	third	third	ADJ
bjos-8668749	130	3	isoform	isoform	NOUN
bjos-8668749	130	4	,	,	PUNCT
bjos-8668749	130	5	called	call	VERB
bjos-8668749	130	6	β1d	β1d	NOUN
bjos-8668749	130	7	,	,	PUNCT
bjos-8668749	130	8	is	be	AUX
bjos-8668749	130	9	a	a	DET
bjos-8668749	130	10	striated	striated	ADJ
bjos-8668749	130	11	muscle	muscle	NOUN
bjos-8668749	130	12	-	-	PUNCT
bjos-8668749	130	13	specific	specific	ADJ
bjos-8668749	130	14	isoform	isoform	NOUN
bjos-8668749	130	15	,	,	PUNCT
bjos-8668749	130	16	which	which	PRON
bjos-8668749	130	17	replaces	replace	VERB
bjos-8668749	130	18	the	the	DET
bjos-8668749	130	19	canonical	canonical	ADJ
bjos-8668749	130	20	β1a	β1a	PRON
bjos-8668749	130	21	isoform	isoform	NOUN
bjos-8668749	130	22	in	in	ADP
bjos-8668749	130	23	cardiac	cardiac	ADJ
bjos-8668749	130	24	and	and	CCONJ
bjos-8668749	130	25	skeletal	skeletal	ADJ
bjos-8668749	130	26	muscle	muscle	NOUN
bjos-8668749	130	27	cells	cell	NOUN
bjos-8668749	130	28	.	.	PUNCT
bjos-8668749	131	1	this	this	DET
bjos-8668749	131	2	isoform	isoform	NOUN
bjos-8668749	131	3	is	be	AUX
bjos-8668749	131	4	produced	produce	VERB
bjos-8668749	131	5	from	from	ADP
bjos-8668749	131	6	splicing	splice	VERB
bjos-8668749	131	7	into	into	ADP
bjos-8668749	131	8	a	a	DET
bjos-8668749	131	9	new	new	ADJ
bjos-8668749	131	10	additional	additional	ADJ
bjos-8668749	131	11	exon	exon	NOUN
bjos-8668749	131	12	between	between	ADP
bjos-8668749	131	13	exons	exon	NOUN
bjos-8668749	131	14	6	6	NUM
bjos-8668749	131	15	and	and	CCONJ
bjos-8668749	131	16	7	7	NUM
bjos-8668749	131	17	.	.	PUNCT
bjos-8668749	132	1	the	the	DET
bjos-8668749	132	2	cytoplasmic	cytoplasmic	ADJ
bjos-8668749	132	3	domain	domain	NOUN
bjos-8668749	132	4	of	of	ADP
bjos-8668749	132	5	β1d	β1d	PUNCT
bjos-8668749	132	6	integrin	integrin	NOUN
bjos-8668749	132	7	replaces	replace	VERB
bjos-8668749	132	8	the	the	DET
bjos-8668749	132	9	21	21	NUM
bjos-8668749	132	10	distal	distal	ADJ
bjos-8668749	132	11	amino	amino	ADJ
bjos-8668749	132	12	acids	acid	NOUN
bjos-8668749	132	13	(	(	PUNCT
bjos-8668749	132	14	present	present	ADJ
bjos-8668749	132	15	in	in	ADP
bjos-8668749	132	16	β1a	β1a	NUM
bjos-8668749	132	17	integrin	integrin	NOUN
bjos-8668749	132	18	)	)	PUNCT
bjos-8668749	132	19	with	with	ADP
bjos-8668749	132	20	an	an	DET
bjos-8668749	132	21	alternative	alternative	ADJ
bjos-8668749	132	22	stretch	stretch	NOUN
bjos-8668749	132	23	of	of	ADP
bjos-8668749	132	24	24	24	NUM
bjos-8668749	132	25	amino	amino	ADJ
bjos-8668749	132	26	acids	acid	NOUN
bjos-8668749	132	27	(	(	PUNCT
bjos-8668749	132	28	13	13	NUM
bjos-8668749	132	29	unique)25	unique)25	PROPN
bjos-8668749	132	30	-	-	PUNCT
bjos-8668749	132	31	28	28	NUM
bjos-8668749	132	32	.	.	PUNCT
bjos-8668749	133	1	the	the	DET
bjos-8668749	133	2	β1d	β1d	NOUN
bjos-8668749	133	3	integrin	integrin	NOUN
bjos-8668749	133	4	is	be	AUX
bjos-8668749	133	5	developmentally	developmentally	ADV
bjos-8668749	133	6	regulated	regulate	VERB
bjos-8668749	133	7	during	during	ADP
bjos-8668749	133	8	myofibrillogenesis	myofibrillogenesis	NOUN
bjos-8668749	133	9	,	,	PUNCT
bjos-8668749	133	10	appearing	appear	VERB
bjos-8668749	133	11	immediately	immediately	ADV
bjos-8668749	133	12	after	after	ADP
bjos-8668749	133	13	myoblast	myoblast	ADJ
bjos-8668749	133	14	fusion	fusion	NOUN
bjos-8668749	133	15	in	in	ADP
bjos-8668749	133	16	the	the	DET
bjos-8668749	133	17	c2c12	c2c12	NOUN
bjos-8668749	133	18	cell	cell	NOUN
bjos-8668749	133	19	with	with	ADP
bjos-8668749	133	20	increasing	increase	VERB
bjos-8668749	133	21	levels	level	NOUN
bjos-8668749	133	22	throughout	throughout	ADP
bjos-8668749	133	23	myofibrillar	myofibrillar	ADJ
bjos-8668749	133	24	differentiation26	differentiation26	NOUN
bjos-8668749	133	25	.	.	PUNCT
bjos-8668749	134	1	the	the	DET
bjos-8668749	134	2	β1d	β1d	NOUN
bjos-8668749	134	3	integrin	integrin	NOUN
bjos-8668749	134	4	is	be	AUX
bjos-8668749	134	5	located	locate	VERB
bjos-8668749	134	6	specifically	specifically	ADV
bjos-8668749	134	7	in	in	ADP
bjos-8668749	134	8	costomeres	costomere	NOUN
bjos-8668749	134	9	and	and	CCONJ
bjos-8668749	134	10	intercalary	intercalary	ADJ
bjos-8668749	134	11	disks	disk	NOUN
bjos-8668749	134	12	of	of	ADP
bjos-8668749	134	13	cardiac	cardiac	ADJ
bjos-8668749	134	14	muscle	muscle	NOUN
bjos-8668749	134	15	,	,	PUNCT
bjos-8668749	134	16	myotendinous	myotendinous	ADJ
bjos-8668749	134	17	junctions	junction	NOUN
bjos-8668749	134	18	and	and	CCONJ
bjos-8668749	134	19	neuromuscular	neuromuscular	ADJ
bjos-8668749	134	20	junctions	junction	NOUN
bjos-8668749	134	21	of	of	ADP
bjos-8668749	134	22	skeletal	skeletal	ADJ
bjos-8668749	134	23	muscle	muscle	NOUN
bjos-8668749	134	24	,	,	PUNCT
bjos-8668749	134	25	and	and	CCONJ
bjos-8668749	134	26	appears	appear	VERB
bjos-8668749	134	27	to	to	PART
bjos-8668749	134	28	function	function	VERB
bjos-8668749	134	29	in	in	ADP
bjos-8668749	134	30	general	general	ADJ
bjos-8668749	134	31	like	like	ADP
bjos-8668749	134	32	other	other	ADJ
bjos-8668749	134	33	integrins	integrin	NOUN
bjos-8668749	134	34	,	,	PUNCT
bjos-8668749	134	35	such	such	ADJ
bjos-8668749	134	36	as	as	ADP
bjos-8668749	134	37	the	the	DET
bjos-8668749	134	38	β1d	β1d	PUNCT
bjos-8668749	134	39	integrin	integrin	NOUN
bjos-8668749	134	40	cluster	cluster	NOUN
bjos-8668749	134	41	on	on	ADP
bjos-8668749	134	42	the	the	DET
bjos-8668749	134	43	surface	surface	NOUN
bjos-8668749	134	44	of	of	ADP
bjos-8668749	134	45	skeletal	skeletal	ADJ
bjos-8668749	134	46	muscle28	muscle28	NOUN
bjos-8668749	134	47	.	.	PUNCT
bjos-8668749	135	1	7	7	NUM
bjos-8668749	135	2	nascimento	nascimento	PROPN
bjos-8668749	135	3	et	et	PROPN
bjos-8668749	135	4	al	al	PROPN
bjos-8668749	135	5	.	.	PROPN
bjos-8668749	136	1	braz	braz	PROPN
bjos-8668749	137	1	j	j	PROPN
bjos-8668749	137	2	oral	oral	PROPN
bjos-8668749	137	3	sci	sci	PROPN
bjos-8668749	137	4	.	.	PUNCT
bjos-8668749	138	1	2023;22	2023;22	NUM
bjos-8668749	138	2	:	:	PUNCT
bjos-8668749	138	3	e238749	e238749	VERB
bjos-8668749	138	4	the	the	DET
bjos-8668749	138	5	role	role	NOUN
bjos-8668749	138	6	of	of	ADP
bjos-8668749	138	7	fibronectin	fibronectin	NOUN
bjos-8668749	138	8	in	in	ADP
bjos-8668749	138	9	the	the	DET
bjos-8668749	138	10	osseointegration	osseointegration	NOUN
bjos-8668749	138	11	process	process	NOUN
bjos-8668749	138	12	fibronectin	fibronectin	NOUN
bjos-8668749	138	13	(	(	PUNCT
bjos-8668749	138	14	fn	fn	NOUN
bjos-8668749	138	15	)	)	PUNCT
bjos-8668749	138	16	is	be	AUX
bjos-8668749	138	17	one	one	NUM
bjos-8668749	138	18	of	of	ADP
bjos-8668749	138	19	the	the	DET
bjos-8668749	138	20	most	most	ADV
bjos-8668749	138	21	widely	widely	ADV
bjos-8668749	138	22	studied	study	VERB
bjos-8668749	138	23	glycoproteins	glycoprotein	NOUN
bjos-8668749	138	24	.	.	PUNCT
bjos-8668749	139	1	it	it	PRON
bjos-8668749	139	2	belongs	belong	VERB
bjos-8668749	139	3	to	to	ADP
bjos-8668749	139	4	a	a	DET
bjos-8668749	139	5	family	family	NOUN
bjos-8668749	139	6	of	of	ADP
bjos-8668749	139	7	20	20	NUM
bjos-8668749	139	8	high	high	ADJ
bjos-8668749	139	9	molecular	molecular	ADJ
bjos-8668749	139	10	weight	weight	NOUN
bjos-8668749	139	11	glycoproteins	glycoprotein	NOUN
bjos-8668749	139	12	(	(	PUNCT
bjos-8668749	139	13	440	440	NUM
bjos-8668749	139	14	-	-	SYM
bjos-8668749	139	15	500kda	500kda	NUM
bjos-8668749	139	16	)	)	PUNCT
bjos-8668749	139	17	with	with	ADP
bjos-8668749	139	18	about	about	ADV
bjos-8668749	139	19	5	5	NUM
bjos-8668749	139	20	%	%	NOUN
bjos-8668749	139	21	carbohydrates	carbohydrate	NOUN
bjos-8668749	139	22	.	.	PUNCT
bjos-8668749	140	1	fn	fn	PROPN
bjos-8668749	140	2	is	be	AUX
bjos-8668749	140	3	an	an	DET
bjos-8668749	140	4	elongated	elongate	VERB
bjos-8668749	140	5	(	(	PUNCT
bjos-8668749	140	6	2	2	NUM
bjos-8668749	140	7	similar	similar	ADJ
bjos-8668749	140	8	polypeptide	polypeptide	ADJ
bjos-8668749	140	9	subunits	subunit	NOUN
bjos-8668749	140	10	)	)	PUNCT
bjos-8668749	140	11	dimeric	dimeric	ADJ
bjos-8668749	140	12	glycoprotein	glycoprotein	NOUN
bjos-8668749	140	13	(	(	PUNCT
bjos-8668749	140	14	figure	figure	NOUN
bjos-8668749	140	15	2	2	NUM
bjos-8668749	140	16	)	)	PUNCT
bjos-8668749	140	17	found	find	VERB
bjos-8668749	140	18	in	in	ADP
bjos-8668749	140	19	all	all	DET
bjos-8668749	140	20	vertebrates	vertebrate	NOUN
bjos-8668749	140	21	in	in	ADP
bjos-8668749	140	22	soluble	soluble	ADJ
bjos-8668749	140	23	(	(	PUNCT
bjos-8668749	140	24	blood	blood	NOUN
bjos-8668749	140	25	plasma	plasma	NOUN
bjos-8668749	140	26	and	and	CCONJ
bjos-8668749	140	27	other	other	ADJ
bjos-8668749	140	28	fluids	fluid	NOUN
bjos-8668749	140	29	)	)	PUNCT
bjos-8668749	140	30	and	and	CCONJ
bjos-8668749	140	31	insoluble	insoluble	ADJ
bjos-8668749	140	32	(	(	PUNCT
bjos-8668749	140	33	associated	associate	VERB
bjos-8668749	140	34	with	with	ADP
bjos-8668749	140	35	the	the	DET
bjos-8668749	140	36	matrix	matrix	NOUN
bjos-8668749	140	37	extracellular	extracellular	ADJ
bjos-8668749	140	38	meshwork	meshwork	NOUN
bjos-8668749	140	39	)	)	PUNCT
bjos-8668749	140	40	forms29	forms29	PROPN
bjos-8668749	140	41	.	.	PUNCT
bjos-8668749	141	1	legend	legend	NOUN
bjos-8668749	141	2	:	:	PUNCT
bjos-8668749	142	1	representation	representation	NOUN
bjos-8668749	142	2	of	of	ADP
bjos-8668749	142	3	fibronectin	fibronectin	NOUN
bjos-8668749	142	4	showing	show	VERB
bjos-8668749	142	5	its	its	PRON
bjos-8668749	142	6	three	three	NUM
bjos-8668749	142	7	modules	module	NOUN
bjos-8668749	142	8	(	(	PUNCT
bjos-8668749	142	9	type	type	NOUN
bjos-8668749	142	10	i	i	PROPN
bjos-8668749	142	11	,	,	PUNCT
bjos-8668749	142	12	ii	ii	PROPN
bjos-8668749	142	13	and	and	CCONJ
bjos-8668749	142	14	iii	iii	NUM
bjos-8668749	142	15	)	)	PUNCT
bjos-8668749	142	16	.	.	PUNCT
bjos-8668749	143	1	highlighting	highlight	VERB
bjos-8668749	143	2	its	its	PRON
bjos-8668749	143	3	specific	specific	ADJ
bjos-8668749	143	4	domains	domain	NOUN
bjos-8668749	143	5	and	and	CCONJ
bjos-8668749	143	6	ligands	ligand	NOUN
bjos-8668749	143	7	.	.	PUNCT
bjos-8668749	144	1	adapted	adapt	VERB
bjos-8668749	144	2	from	from	ADP
bjos-8668749	144	3	biorender	biorender	NOUN
bjos-8668749	144	4	(	(	PUNCT
bjos-8668749	144	5	2022	2022	NUM
bjos-8668749	144	6	)	)	PUNCT
bjos-8668749	144	7	.	.	PUNCT
bjos-8668749	145	1	figure	figure	NOUN
bjos-8668749	145	2	2	2	NUM
bjos-8668749	145	3	.	.	PUNCT
bjos-8668749	145	4	fibronectin	fibronectin	NOUN
bjos-8668749	145	5	structure	structure	NOUN
bjos-8668749	145	6	schematic	schematic	ADJ
bjos-8668749	145	7	each	each	DET
bjos-8668749	145	8	fibronectin	fibronectin	NOUN
bjos-8668749	145	9	subunit	subunit	NOUN
bjos-8668749	145	10	has	have	VERB
bjos-8668749	145	11	an	an	DET
bjos-8668749	145	12	amino	amino	NOUN
bjos-8668749	145	13	-	-	PUNCT
bjos-8668749	145	14	terminal	terminal	ADJ
bjos-8668749	145	15	portion	portion	NOUN
bjos-8668749	145	16	and	and	CCONJ
bjos-8668749	145	17	a	a	DET
bjos-8668749	145	18	carboxy	carboxy	ADJ
bjos-8668749	145	19	-	-	PUNCT
bjos-8668749	145	20	terminal	terminal	ADJ
bjos-8668749	145	21	portion	portion	NOUN
bjos-8668749	145	22	.	.	PUNCT
bjos-8668749	146	1	disulfide	disulfide	NOUN
bjos-8668749	146	2	bridges	bridge	NOUN
bjos-8668749	146	3	connect	connect	VERB
bjos-8668749	146	4	one	one	NUM
bjos-8668749	146	5	subunit	subunit	NOUN
bjos-8668749	146	6	to	to	ADP
bjos-8668749	146	7	the	the	DET
bjos-8668749	146	8	other	other	ADJ
bjos-8668749	146	9	in	in	ADP
bjos-8668749	146	10	the	the	DET
bjos-8668749	146	11	region	region	NOUN
bjos-8668749	146	12	near	near	ADP
bjos-8668749	146	13	the	the	DET
bjos-8668749	146	14	each	each	DET
bjos-8668749	146	15	carboxyterminal	carboxyterminal	ADJ
bjos-8668749	146	16	portion	portion	NOUN
bjos-8668749	146	17	.	.	PUNCT
bjos-8668749	147	1	they	they	PRON
bjos-8668749	147	2	have	have	VERB
bjos-8668749	147	3	folds	fold	NOUN
bjos-8668749	147	4	that	that	PRON
bjos-8668749	147	5	lead	lead	VERB
bjos-8668749	147	6	to	to	ADP
bjos-8668749	147	7	structural	structural	ADJ
bjos-8668749	147	8	remodeling	remodeling	NOUN
bjos-8668749	147	9	and	and	CCONJ
bjos-8668749	147	10	various	various	ADJ
bjos-8668749	147	11	conformations	conformation	NOUN
bjos-8668749	147	12	according	accord	VERB
bjos-8668749	147	13	to	to	ADP
bjos-8668749	147	14	the	the	DET
bjos-8668749	147	15	medium30	medium30	NOUN
bjos-8668749	147	16	.	.	PUNCT
bjos-8668749	148	1	the	the	DET
bjos-8668749	148	2	subunits	subunit	NOUN
bjos-8668749	148	3	have	have	VERB
bjos-8668749	148	4	a	a	DET
bjos-8668749	148	5	modular	modular	ADJ
bjos-8668749	148	6	architecture	architecture	NOUN
bjos-8668749	148	7	formed	form	VERB
bjos-8668749	148	8	by	by	ADP
bjos-8668749	148	9	the	the	DET
bjos-8668749	148	10	repetition	repetition	NOUN
bjos-8668749	148	11	of	of	ADP
bjos-8668749	148	12	3	3	NUM
bjos-8668749	148	13	structures	structure	NOUN
bjos-8668749	148	14	types	type	NOUN
bjos-8668749	148	15	(	(	PUNCT
bjos-8668749	148	16	type	type	NOUN
bjos-8668749	148	17	i	i	PROPN
bjos-8668749	148	18	,	,	PUNCT
bjos-8668749	148	19	ii	ii	PROPN
bjos-8668749	148	20	,	,	PUNCT
bjos-8668749	148	21	and	and	CCONJ
bjos-8668749	148	22	iii	iii	X
bjos-8668749	148	23	)	)	PUNCT
bjos-8668749	148	24	separated	separate	VERB
bjos-8668749	148	25	by	by	ADP
bjos-8668749	148	26	short	short	ADJ
bjos-8668749	148	27	stretches	stretch	NOUN
bjos-8668749	148	28	of	of	ADP
bjos-8668749	148	29	flexible	flexible	ADJ
bjos-8668749	148	30	polypeptide	polypeptide	ADJ
bjos-8668749	148	31	chains	chain	NOUN
bjos-8668749	148	32	.	.	PUNCT
bjos-8668749	149	1	each	each	DET
bjos-8668749	149	2	subunit	subunit	NOUN
bjos-8668749	149	3	has	have	VERB
bjos-8668749	149	4	40	40	NUM
bjos-8668749	149	5	-	-	SYM
bjos-8668749	149	6	90	90	NUM
bjos-8668749	149	7	amino	amino	NOUN
bjos-8668749	149	8	acids	acid	NOUN
bjos-8668749	149	9	forming	form	VERB
bjos-8668749	149	10	the	the	DET
bjos-8668749	149	11	various	various	ADJ
bjos-8668749	149	12	α	α	NOUN
bjos-8668749	149	13	and	and	CCONJ
bjos-8668749	149	14	β	β	NOUN
bjos-8668749	149	15	domains	domain	NOUN
bjos-8668749	149	16	.	.	PUNCT
bjos-8668749	150	1	in	in	ADP
bjos-8668749	150	2	the	the	DET
bjos-8668749	150	3	subunits	subunit	NOUN
bjos-8668749	150	4	there	there	PRON
bjos-8668749	150	5	are	be	VERB
bjos-8668749	150	6	regions	region	NOUN
bjos-8668749	150	7	of	of	ADP
bjos-8668749	150	8	adhesion	adhesion	NOUN
bjos-8668749	150	9	with	with	ADP
bjos-8668749	150	10	non	non	ADJ
bjos-8668749	150	11	-	-	ADJ
bjos-8668749	150	12	epithelial	epithelial	ADJ
bjos-8668749	150	13	cells	cell	NOUN
bjos-8668749	150	14	,	,	PUNCT
bjos-8668749	150	15	with	with	ADP
bjos-8668749	150	16	other	other	ADJ
bjos-8668749	150	17	fibronectin	fibronectin	NOUN
bjos-8668749	150	18	molecules	molecule	NOUN
bjos-8668749	150	19	and	and	CCONJ
bjos-8668749	150	20	with	with	ADP
bjos-8668749	150	21	extracellular	extracellular	ADJ
bjos-8668749	150	22	matrix	matrix	NOUN
bjos-8668749	150	23	components31	components31	NOUN
bjos-8668749	150	24	.	.	PUNCT
bjos-8668749	151	1	in	in	ADP
bjos-8668749	151	2	the	the	DET
bjos-8668749	151	3	type	type	NOUN
bjos-8668749	151	4	iii	iii	NOUN
bjos-8668749	151	5	structure	structure	NOUN
bjos-8668749	151	6	,	,	PUNCT
bjos-8668749	151	7	with	with	ADP
bjos-8668749	151	8	about	about	ADV
bjos-8668749	151	9	90	90	NUM
bjos-8668749	151	10	amino	amino	NOUN
bjos-8668749	151	11	acid	acid	NOUN
bjos-8668749	151	12	residues	residue	NOUN
bjos-8668749	151	13	,	,	PUNCT
bjos-8668749	151	14	is	be	AUX
bjos-8668749	151	15	located	locate	VERB
bjos-8668749	151	16	the	the	DET
bjos-8668749	151	17	rgd	rgd	NOUN
bjos-8668749	151	18	sequence	sequence	NOUN
bjos-8668749	151	19	,	,	PUNCT
bjos-8668749	151	20	which	which	PRON
bjos-8668749	151	21	is	be	AUX
bjos-8668749	151	22	specific	specific	ADJ
bjos-8668749	151	23	for	for	ADP
bjos-8668749	151	24	adhesion	adhesion	NOUN
bjos-8668749	151	25	to	to	ADP
bjos-8668749	151	26	the	the	DET
bjos-8668749	151	27	cell	cell	NOUN
bjos-8668749	151	28	surface	surface	NOUN
bjos-8668749	151	29	.	.	PUNCT
bjos-8668749	152	1	the	the	DET
bjos-8668749	152	2	rgd	rgd	PROPN
bjos-8668749	152	3	region	region	NOUN
bjos-8668749	152	4	8	8	NUM
bjos-8668749	152	5	nascimento	nascimento	PROPN
bjos-8668749	152	6	et	et	PROPN
bjos-8668749	152	7	al	al	PROPN
bjos-8668749	152	8	.	.	PROPN
bjos-8668749	152	9	braz	braz	PROPN
bjos-8668749	152	10	j	j	PROPN
bjos-8668749	152	11	oral	oral	PROPN
bjos-8668749	152	12	sci	sci	PROPN
bjos-8668749	152	13	.	.	PUNCT
bjos-8668749	153	1	2023;22	2023;22	NUM
bjos-8668749	153	2	:	:	PUNCT
bjos-8668749	153	3	e238749	e238749	NUM
bjos-8668749	153	4	of	of	ADP
bjos-8668749	153	5	fn	fn	NOUN
bjos-8668749	153	6	is	be	AUX
bjos-8668749	153	7	recognized	recognize	VERB
bjos-8668749	153	8	by	by	ADP
bjos-8668749	153	9	and	and	CCONJ
bjos-8668749	153	10	binds	bind	VERB
bjos-8668749	153	11	to	to	ADP
bjos-8668749	153	12	eukaryotic	eukaryotic	ADJ
bjos-8668749	153	13	cells	cell	NOUN
bjos-8668749	153	14	via	via	ADP
bjos-8668749	153	15	cell	cell	NOUN
bjos-8668749	153	16	membrane	membrane	NOUN
bjos-8668749	153	17	protein	protein	NOUN
bjos-8668749	153	18	receptors	receptor	NOUN
bjos-8668749	153	19	called	call	VERB
bjos-8668749	153	20	integrins	integrin	NOUN
bjos-8668749	153	21	.	.	PUNCT
bjos-8668749	154	1	it	it	PRON
bjos-8668749	154	2	can	can	AUX
bjos-8668749	154	3	bind	bind	VERB
bjos-8668749	154	4	to	to	ADP
bjos-8668749	154	5	other	other	ADJ
bjos-8668749	154	6	molecules	molecule	NOUN
bjos-8668749	154	7	such	such	ADJ
bjos-8668749	154	8	as	as	ADP
bjos-8668749	154	9	collagen	collagen	NOUN
bjos-8668749	154	10	fibers	fiber	NOUN
bjos-8668749	154	11	,	,	PUNCT
bjos-8668749	154	12	fibrin	fibrin	NOUN
bjos-8668749	154	13	,	,	PUNCT
bjos-8668749	154	14	and	and	CCONJ
bjos-8668749	154	15	heparin	heparin	NOUN
bjos-8668749	154	16	.	.	PUNCT
bjos-8668749	155	1	fn	fn	AUX
bjos-8668749	155	2	,	,	PUNCT
bjos-8668749	155	3	being	be	AUX
bjos-8668749	155	4	an	an	DET
bjos-8668749	155	5	adhesive	adhesive	ADJ
bjos-8668749	155	6	protein	protein	NOUN
bjos-8668749	155	7	,	,	PUNCT
bjos-8668749	155	8	mediates	mediate	VERB
bjos-8668749	155	9	the	the	DET
bjos-8668749	155	10	cells	cell	NOUN
bjos-8668749	155	11	adhesion	adhesion	NOUN
bjos-8668749	155	12	to	to	PART
bjos-8668749	155	13	biomaterials30	biomaterials30	VERB
bjos-8668749	155	14	.	.	PUNCT
bjos-8668749	156	1	integrin	integrin	NOUN
bjos-8668749	156	2	has	have	VERB
bjos-8668749	156	3	low	low	ADJ
bjos-8668749	156	4	-	-	PUNCT
bjos-8668749	156	5	affinity	affinity	NOUN
bjos-8668749	156	6	binding	bind	VERB
bjos-8668749	156	7	domains	domain	NOUN
bjos-8668749	156	8	for	for	ADP
bjos-8668749	156	9	divalent	divalent	ADJ
bjos-8668749	156	10	cations	cation	NOUN
bjos-8668749	156	11	,	,	PUNCT
bjos-8668749	156	12	which	which	PRON
bjos-8668749	156	13	in	in	ADP
bjos-8668749	156	14	turn	turn	NOUN
bjos-8668749	156	15	form	form	VERB
bjos-8668749	156	16	a	a	DET
bjos-8668749	156	17	ternary	ternary	ADJ
bjos-8668749	156	18	complex	complex	NOUN
bjos-8668749	156	19	with	with	ADP
bjos-8668749	156	20	the	the	DET
bjos-8668749	156	21	divalent	divalent	ADJ
bjos-8668749	156	22	ion	ion	NOUN
bjos-8668749	156	23	bound	bind	VERB
bjos-8668749	156	24	to	to	ADP
bjos-8668749	156	25	the	the	DET
bjos-8668749	156	26	receptor	receptor	NOUN
bjos-8668749	156	27	.	.	PUNCT
bjos-8668749	157	1	at	at	ADP
bjos-8668749	157	2	contacts	contact	NOUN
bjos-8668749	157	3	between	between	ADP
bjos-8668749	157	4	rgd	rgd	PROPN
bjos-8668749	157	5	and	and	CCONJ
bjos-8668749	157	6	integrin	integrin	NOUN
bjos-8668749	157	7	,	,	PUNCT
bjos-8668749	157	8	the	the	DET
bjos-8668749	157	9	divalent	divalent	NOUN
bjos-8668749	157	10	ion	ion	NOUN
bjos-8668749	157	11	is	be	AUX
bjos-8668749	157	12	displaced	displace	VERB
bjos-8668749	157	13	.	.	PUNCT
bjos-8668749	158	1	figure	figure	NOUN
bjos-8668749	158	2	3	3	NUM
bjos-8668749	158	3	shows	show	VERB
bjos-8668749	158	4	a	a	DET
bjos-8668749	158	5	schematic	schematic	ADJ
bjos-8668749	158	6	diagram	diagram	NOUN
bjos-8668749	158	7	depicting	depict	VERB
bjos-8668749	158	8	the	the	DET
bjos-8668749	158	9	connection	connection	NOUN
bjos-8668749	158	10	between	between	ADP
bjos-8668749	158	11	the	the	DET
bjos-8668749	158	12	cell	cell	NOUN
bjos-8668749	158	13	interior	interior	NOUN
bjos-8668749	158	14	and	and	CCONJ
bjos-8668749	158	15	the	the	DET
bjos-8668749	158	16	matrix	matrix	NOUN
bjos-8668749	158	17	extracellular	extracellular	ADJ
bjos-8668749	158	18	via	via	ADP
bjos-8668749	158	19	the	the	DET
bjos-8668749	158	20	integrin	integrin	NOUN
bjos-8668749	158	21	.	.	PUNCT
bjos-8668749	159	1	integrin	integrin	PROPN
bjos-8668749	159	2	binds	bind	VERB
bjos-8668749	159	3	directly	directly	ADV
bjos-8668749	159	4	to	to	ADP
bjos-8668749	159	5	an	an	DET
bjos-8668749	159	6	extracellular	extracellular	ADJ
bjos-8668749	159	7	protein	protein	NOUN
bjos-8668749	159	8	such	such	ADJ
bjos-8668749	159	9	as	as	ADP
bjos-8668749	159	10	fn	fn	NOUN
bjos-8668749	159	11	,	,	PUNCT
bjos-8668749	159	12	its	its	PRON
bjos-8668749	159	13	intracellular	intracellular	ADJ
bjos-8668749	159	14	tail	tail	NOUN
bjos-8668749	159	15	binds	bind	VERB
bjos-8668749	159	16	to	to	ADP
bjos-8668749	159	17	an	an	DET
bjos-8668749	159	18	adaptor	adaptor	NOUN
bjos-8668749	159	19	protein	protein	NOUN
bjos-8668749	159	20	such	such	ADJ
bjos-8668749	159	21	as	as	ADP
bjos-8668749	159	22	talin	talin	NOUN
bjos-8668749	159	23	,	,	PUNCT
bjos-8668749	159	24	which	which	PRON
bjos-8668749	159	25	in	in	ADP
bjos-8668749	159	26	turn	turn	NOUN
bjos-8668749	159	27	binds	bind	VERB
bjos-8668749	159	28	to	to	ADP
bjos-8668749	159	29	actin	actin	PROPN
bjos-8668749	159	30	filaments31,32	filaments31,32	PROPN
bjos-8668749	159	31	.	.	PUNCT
bjos-8668749	160	1	legend	legend	PROPN
bjos-8668749	160	2	:	:	PUNCT
bjos-8668749	161	1	representation	representation	NOUN
bjos-8668749	161	2	of	of	ADP
bjos-8668749	161	3	fibronectin	fibronectin	NOUN
bjos-8668749	161	4	binding	bind	VERB
bjos-8668749	161	5	to	to	ADP
bjos-8668749	161	6	integrin	integrin	NOUN
bjos-8668749	161	7	and	and	CCONJ
bjos-8668749	161	8	one	one	NUM
bjos-8668749	161	9	of	of	ADP
bjos-8668749	161	10	its	its	PRON
bjos-8668749	161	11	receptors	receptor	NOUN
bjos-8668749	161	12	in	in	ADP
bjos-8668749	161	13	the	the	DET
bjos-8668749	161	14	cytoplasm	cytoplasm	NOUN
bjos-8668749	161	15	(	(	PUNCT
bjos-8668749	161	16	collagen	collagen	NOUN
bjos-8668749	161	17	fibers	fiber	NOUN
bjos-8668749	161	18	)	)	PUNCT
bjos-8668749	161	19	.	.	PUNCT
bjos-8668749	162	1	adapted	adapt	VERB
bjos-8668749	162	2	from	from	ADP
bjos-8668749	162	3	biorender	biorender	NOUN
bjos-8668749	162	4	(	(	PUNCT
bjos-8668749	162	5	2022	2022	NUM
bjos-8668749	162	6	)	)	PUNCT
bjos-8668749	162	7	.	.	PUNCT
bjos-8668749	163	1	figure	figure	VERB
bjos-8668749	163	2	3	3	NUM
bjos-8668749	163	3	.	.	PUNCT
bjos-8668749	163	4	fibronectin	fibronectin	NOUN
bjos-8668749	163	5	interactions	interaction	NOUN
bjos-8668749	163	6	schematic	schematic	ADJ
bjos-8668749	163	7	9	9	NUM
bjos-8668749	163	8	nascimento	nascimento	PROPN
bjos-8668749	163	9	et	et	PROPN
bjos-8668749	163	10	al	al	PROPN
bjos-8668749	163	11	.	.	PROPN
bjos-8668749	164	1	braz	braz	PROPN
bjos-8668749	164	2	j	j	PROPN
bjos-8668749	164	3	oral	oral	PROPN
bjos-8668749	164	4	sci	sci	PROPN
bjos-8668749	164	5	.	.	PUNCT
bjos-8668749	165	1	2023;22	2023;22	NUM
bjos-8668749	165	2	:	:	PUNCT
bjos-8668749	165	3	e238749	e238749	PROPN
bjos-8668749	165	4	when	when	SCONJ
bjos-8668749	165	5	cells	cell	NOUN
bjos-8668749	165	6	come	come	VERB
bjos-8668749	165	7	into	into	ADP
bjos-8668749	165	8	contact	contact	NOUN
bjos-8668749	165	9	with	with	ADP
bjos-8668749	165	10	the	the	DET
bjos-8668749	165	11	protein	protein	NOUN
bjos-8668749	165	12	layer	layer	NOUN
bjos-8668749	165	13	adsorbed	adsorb	VERB
bjos-8668749	165	14	on	on	ADP
bjos-8668749	165	15	the	the	DET
bjos-8668749	165	16	biomaterial	biomaterial	ADJ
bjos-8668749	165	17	surface	surface	NOUN
bjos-8668749	165	18	,	,	PUNCT
bjos-8668749	165	19	they	they	PRON
bjos-8668749	165	20	attach	attach	VERB
bjos-8668749	165	21	themselves	themselves	PRON
bjos-8668749	165	22	through	through	ADP
bjos-8668749	165	23	physicochemical	physicochemical	ADJ
bjos-8668749	165	24	interactions	interaction	NOUN
bjos-8668749	165	25	such	such	ADJ
bjos-8668749	165	26	as	as	ADP
bjos-8668749	165	27	ionic	ionic	ADJ
bjos-8668749	165	28	and	and	CCONJ
bjos-8668749	165	29	van	van	PROPN
bjos-8668749	165	30	der	der	ADJ
bjos-8668749	165	31	walls	wall	NOUN
bjos-8668749	165	32	forces	force	NOUN
bjos-8668749	165	33	.	.	PUNCT
bjos-8668749	166	1	this	this	PRON
bjos-8668749	166	2	is	be	AUX
bjos-8668749	166	3	followed	follow	VERB
bjos-8668749	166	4	by	by	ADP
bjos-8668749	166	5	cell	cell	NOUN
bjos-8668749	166	6	-	-	PUNCT
bjos-8668749	166	7	binding	bind	VERB
bjos-8668749	166	8	recognition	recognition	NOUN
bjos-8668749	166	9	on	on	ADP
bjos-8668749	166	10	these	these	DET
bjos-8668749	166	11	proteins	protein	NOUN
bjos-8668749	166	12	that	that	PRON
bjos-8668749	166	13	is	be	AUX
bjos-8668749	166	14	mediated	mediate	VERB
bjos-8668749	166	15	by	by	ADP
bjos-8668749	166	16	integrins32	integrins32	NOUN
bjos-8668749	166	17	.	.	PUNCT
bjos-8668749	167	1	upon	upon	SCONJ
bjos-8668749	167	2	making	make	VERB
bjos-8668749	167	3	bonds	bond	NOUN
bjos-8668749	167	4	with	with	ADP
bjos-8668749	167	5	their	their	PRON
bjos-8668749	167	6	specific	specific	ADJ
bjos-8668749	167	7	intracellular	intracellular	ADJ
bjos-8668749	167	8	receptors	receptor	NOUN
bjos-8668749	167	9	,	,	PUNCT
bjos-8668749	167	10	the	the	DET
bjos-8668749	167	11	integrins	integrin	NOUN
bjos-8668749	167	12	rapidly	rapidly	ADV
bjos-8668749	167	13	make	make	VERB
bjos-8668749	167	14	contact	contact	NOUN
bjos-8668749	167	15	with	with	ADP
bjos-8668749	167	16	the	the	DET
bjos-8668749	167	17	actin	actin	NOUN
bjos-8668749	167	18	filaments	filament	NOUN
bjos-8668749	167	19	network	network	NOUN
bjos-8668749	167	20	of	of	ADP
bjos-8668749	167	21	the	the	DET
bjos-8668749	167	22	cytoskeleton	cytoskeleton	NOUN
bjos-8668749	167	23	and	and	CCONJ
bjos-8668749	167	24	assemble	assemble	VERB
bjos-8668749	167	25	to	to	PART
bjos-8668749	167	26	form	form	VERB
bjos-8668749	167	27	focal	focal	ADJ
bjos-8668749	167	28	adhesions	adhesion	NOUN
bjos-8668749	167	29	.	.	PUNCT
bjos-8668749	168	1	actins	actin	NOUN
bjos-8668749	168	2	filaments	filament	NOUN
bjos-8668749	168	3	are	be	AUX
bjos-8668749	168	4	discrete	discrete	ADJ
bjos-8668749	168	5	complexes	complex	NOUN
bjos-8668749	168	6	that	that	PRON
bjos-8668749	168	7	contain	contain	VERB
bjos-8668749	168	8	structural	structural	ADJ
bjos-8668749	168	9	and	and	CCONJ
bjos-8668749	168	10	signaling	signal	VERB
bjos-8668749	168	11	molecules	molecule	NOUN
bjos-8668749	168	12	and	and	CCONJ
bjos-8668749	168	13	function	function	NOUN
bjos-8668749	168	14	as	as	ADP
bjos-8668749	168	15	structural	structural	ADJ
bjos-8668749	168	16	links	link	NOUN
bjos-8668749	168	17	between	between	ADP
bjos-8668749	168	18	the	the	DET
bjos-8668749	168	19	cytoskeleton	cytoskeleton	NOUN
bjos-8668749	168	20	and	and	CCONJ
bjos-8668749	168	21	the	the	DET
bjos-8668749	168	22	plasma	plasma	NOUN
bjos-8668749	168	23	membrane	membrane	NOUN
bjos-8668749	168	24	to	to	PART
bjos-8668749	168	25	mediate	mediate	VERB
bjos-8668749	168	26	cell	cell	NOUN
bjos-8668749	168	27	adhesion	adhesion	NOUN
bjos-8668749	168	28	and	and	CCONJ
bjos-8668749	168	29	migration33	migration33	NOUN
bjos-8668749	168	30	.	.	PUNCT
bjos-8668749	169	1	in	in	ADP
bjos-8668749	169	2	conjunction	conjunction	NOUN
bjos-8668749	169	3	with	with	ADP
bjos-8668749	169	4	growth	growth	NOUN
bjos-8668749	169	5	factor	factor	NOUN
bjos-8668749	169	6	receptors	receptor	NOUN
bjos-8668749	169	7	,	,	PUNCT
bjos-8668749	169	8	focal	focal	ADJ
bjos-8668749	169	9	adhesions	adhesion	NOUN
bjos-8668749	169	10	activate	activate	VERB
bjos-8668749	169	11	signaling	signal	VERB
bjos-8668749	169	12	pathways	pathway	NOUN
bjos-8668749	169	13	,	,	PUNCT
bjos-8668749	169	14	which	which	PRON
bjos-8668749	169	15	regulate	regulate	VERB
bjos-8668749	169	16	transcription	transcription	NOUN
bjos-8668749	169	17	factor	factor	NOUN
bjos-8668749	169	18	activity	activity	NOUN
bjos-8668749	169	19	and	and	CCONJ
bjos-8668749	169	20	direct	direct	ADJ
bjos-8668749	169	21	cell	cell	NOUN
bjos-8668749	169	22	proliferation	proliferation	NOUN
bjos-8668749	169	23	and	and	CCONJ
bjos-8668749	169	24	other	other	ADJ
bjos-8668749	169	25	functions34	functions34	NOUN
bjos-8668749	169	26	.	.	PUNCT
bjos-8668749	170	1	on	on	ADP
bjos-8668749	170	2	the	the	DET
bjos-8668749	170	3	cell	cell	NOUN
bjos-8668749	170	4	membrane	membrane	NOUN
bjos-8668749	170	5	and	and	CCONJ
bjos-8668749	170	6	in	in	ADP
bjos-8668749	170	7	the	the	DET
bjos-8668749	170	8	cytoplasm	cytoplasm	NOUN
bjos-8668749	170	9	,	,	PUNCT
bjos-8668749	170	10	there	there	PRON
bjos-8668749	170	11	are	be	VERB
bjos-8668749	170	12	specific	specific	ADJ
bjos-8668749	170	13	receptors	receptor	NOUN
bjos-8668749	170	14	for	for	ADP
bjos-8668749	170	15	the	the	DET
bjos-8668749	170	16	different	different	ADJ
bjos-8668749	170	17	proteins	protein	NOUN
bjos-8668749	170	18	.	.	PUNCT
bjos-8668749	171	1	the	the	DET
bjos-8668749	171	2	main	main	ADJ
bjos-8668749	171	3	receptors	receptor	NOUN
bjos-8668749	171	4	in	in	ADP
bjos-8668749	171	5	cells	cell	NOUN
bjos-8668749	171	6	to	to	PART
bjos-8668749	171	7	bind	bind	VERB
bjos-8668749	171	8	most	most	ADJ
bjos-8668749	171	9	extracellular	extracellular	ADJ
bjos-8668749	171	10	matrix	matrix	NOUN
bjos-8668749	171	11	proteins	protein	NOUN
bjos-8668749	171	12	are	be	AUX
bjos-8668749	171	13	integrins	integrin	NOUN
bjos-8668749	171	14	.	.	PUNCT
bjos-8668749	172	1	integrin	integrin	NOUN
bjos-8668749	172	2	is	be	AUX
bjos-8668749	172	3	a	a	DET
bjos-8668749	172	4	heterodimer	heterodimer	NOUN
bjos-8668749	172	5	formed	form	VERB
bjos-8668749	172	6	by	by	ADP
bjos-8668749	172	7	non	non	ADJ
bjos-8668749	172	8	-	-	ADJ
bjos-8668749	172	9	covalently	covalently	ADV
bjos-8668749	172	10	linked	link	VERB
bjos-8668749	172	11	α	α	PROPN
bjos-8668749	172	12	and	and	CCONJ
bjos-8668749	172	13	β	β	NOUN
bjos-8668749	172	14	chains	chain	NOUN
bjos-8668749	172	15	consisting	consist	VERB
bjos-8668749	172	16	of	of	ADP
bjos-8668749	172	17	several	several	ADJ
bjos-8668749	172	18	domains	domain	NOUN
bjos-8668749	172	19	with	with	ADP
bjos-8668749	172	20	flexible	flexible	ADJ
bjos-8668749	172	21	portions	portion	NOUN
bjos-8668749	172	22	between	between	ADP
bjos-8668749	172	23	them	they	PRON
bjos-8668749	172	24	.	.	PUNCT
bjos-8668749	173	1	it	it	PRON
bjos-8668749	173	2	has	have	VERB
bjos-8668749	173	3	a	a	DET
bjos-8668749	173	4	small	small	ADJ
bjos-8668749	173	5	intracellular	intracellular	ADJ
bjos-8668749	173	6	tail	tail	NOUN
bjos-8668749	173	7	(	(	PUNCT
bjos-8668749	173	8	c	c	NOUN
bjos-8668749	173	9	-	-	PUNCT
bjos-8668749	173	10	terminal	terminal	NOUN
bjos-8668749	173	11	)	)	PUNCT
bjos-8668749	173	12	and	and	CCONJ
bjos-8668749	173	13	a	a	DET
bjos-8668749	173	14	large	large	ADJ
bjos-8668749	173	15	extracellular	extracellular	ADJ
bjos-8668749	173	16	domain	domain	NOUN
bjos-8668749	173	17	(	(	PUNCT
bjos-8668749	173	18	n	n	CCONJ
bjos-8668749	173	19	-	-	PUNCT
bjos-8668749	173	20	terminal	terminal	NOUN
bjos-8668749	173	21	)	)	PUNCT
bjos-8668749	173	22	.	.	PUNCT
bjos-8668749	174	1	the	the	DET
bjos-8668749	174	2	extracellular	extracellular	ADJ
bjos-8668749	174	3	portion	portion	NOUN
bjos-8668749	174	4	recognizes	recognize	VERB
bjos-8668749	174	5	and	and	CCONJ
bjos-8668749	174	6	binds	bind	VERB
bjos-8668749	174	7	to	to	ADP
bjos-8668749	174	8	the	the	DET
bjos-8668749	174	9	rgd	rgd	PROPN
bjos-8668749	174	10	amino	amino	NOUN
bjos-8668749	174	11	acid	acid	NOUN
bjos-8668749	174	12	sequence	sequence	NOUN
bjos-8668749	174	13	in	in	ADP
bjos-8668749	174	14	the	the	DET
bjos-8668749	174	15	ligands	ligand	NOUN
bjos-8668749	174	16	,	,	PUNCT
bjos-8668749	174	17	while	while	SCONJ
bjos-8668749	174	18	the	the	DET
bjos-8668749	174	19	intracellular	intracellular	ADJ
bjos-8668749	174	20	portion	portion	NOUN
bjos-8668749	174	21	binds	bind	VERB
bjos-8668749	174	22	to	to	ADP
bjos-8668749	174	23	a	a	DET
bjos-8668749	174	24	complex	complex	NOUN
bjos-8668749	174	25	of	of	ADP
bjos-8668749	174	26	cytoskeleton	cytoskeleton	NOUN
bjos-8668749	174	27	-	-	PUNCT
bjos-8668749	174	28	associated	associate	VERB
bjos-8668749	174	29	adaptor	adaptor	NOUN
bjos-8668749	174	30	proteins32	proteins32	NOUN
bjos-8668749	174	31	.	.	PUNCT
bjos-8668749	175	1	the	the	DET
bjos-8668749	175	2	integrins	integrin	NOUN
bjos-8668749	175	3	are	be	AUX
bjos-8668749	175	4	activated	activate	VERB
bjos-8668749	175	5	as	as	ADP
bjos-8668749	175	6	a	a	DET
bjos-8668749	175	7	result	result	NOUN
bjos-8668749	175	8	of	of	ADP
bjos-8668749	175	9	the	the	DET
bjos-8668749	175	10	conformational	conformational	ADJ
bjos-8668749	175	11	changes	change	NOUN
bjos-8668749	175	12	.	.	PUNCT
bjos-8668749	176	1	these	these	PRON
bjos-8668749	176	2	,	,	PUNCT
bjos-8668749	176	3	in	in	ADP
bjos-8668749	176	4	turn	turn	NOUN
bjos-8668749	176	5	,	,	PUNCT
bjos-8668749	176	6	enable	enable	VERB
bjos-8668749	176	7	them	they	PRON
bjos-8668749	176	8	to	to	PART
bjos-8668749	176	9	interact	interact	VERB
bjos-8668749	176	10	with	with	ADP
bjos-8668749	176	11	their	their	PRON
bjos-8668749	176	12	potential	potential	ADJ
bjos-8668749	176	13	ligands	ligand	NOUN
bjos-8668749	176	14	.	.	PUNCT
bjos-8668749	177	1	the	the	DET
bjos-8668749	177	2	basis	basis	NOUN
bjos-8668749	177	3	for	for	ADP
bjos-8668749	177	4	this	this	DET
bjos-8668749	177	5	phenomenon	phenomenon	NOUN
bjos-8668749	177	6	is	be	AUX
bjos-8668749	177	7	the	the	DET
bjos-8668749	177	8	regulation	regulation	NOUN
bjos-8668749	177	9	of	of	ADP
bjos-8668749	177	10	structural	structural	ADJ
bjos-8668749	177	11	changes	change	NOUN
bjos-8668749	177	12	at	at	ADP
bjos-8668749	177	13	one	one	NUM
bjos-8668749	177	14	end	end	NOUN
bjos-8668749	177	15	that	that	PRON
bjos-8668749	177	16	are	be	AUX
bjos-8668749	177	17	related	relate	VERB
bjos-8668749	177	18	to	to	ADP
bjos-8668749	177	19	structural	structural	ADJ
bjos-8668749	177	20	changes	change	NOUN
bjos-8668749	177	21	at	at	ADP
bjos-8668749	177	22	the	the	DET
bjos-8668749	177	23	other	other	ADJ
bjos-8668749	177	24	end	end	NOUN
bjos-8668749	177	25	.	.	PUNCT
bjos-8668749	178	1	in	in	ADP
bjos-8668749	178	2	their	their	PRON
bjos-8668749	178	3	inactive	inactive	ADJ
bjos-8668749	178	4	state	state	NOUN
bjos-8668749	178	5	,	,	PUNCT
bjos-8668749	178	6	the	the	DET
bjos-8668749	178	7	intracellular	intracellular	ADJ
bjos-8668749	178	8	portions	portion	NOUN
bjos-8668749	178	9	of	of	ADP
bjos-8668749	178	10	the	the	DET
bjos-8668749	178	11	chains	chain	NOUN
bjos-8668749	178	12	adhere	adhere	VERB
bjos-8668749	178	13	to	to	ADP
bjos-8668749	178	14	each	each	DET
bjos-8668749	178	15	other	other	ADJ
bjos-8668749	178	16	,	,	PUNCT
bjos-8668749	178	17	making	make	VERB
bjos-8668749	178	18	it	it	PRON
bjos-8668749	178	19	difficult	difficult	ADJ
bjos-8668749	178	20	to	to	PART
bjos-8668749	178	21	expose	expose	VERB
bjos-8668749	178	22	and	and	CCONJ
bjos-8668749	178	23	bind	bind	VERB
bjos-8668749	178	24	to	to	ADP
bjos-8668749	178	25	talin	talin	NOUN
bjos-8668749	178	26	,	,	PUNCT
bjos-8668749	178	27	the	the	DET
bjos-8668749	178	28	main	main	ADJ
bjos-8668749	178	29	receptor	receptor	NOUN
bjos-8668749	178	30	protein	protein	NOUN
bjos-8668749	178	31	in	in	ADP
bjos-8668749	178	32	the	the	DET
bjos-8668749	178	33	cytoplasm	cytoplasm	NOUN
bjos-8668749	178	34	.	.	PUNCT
bjos-8668749	179	1	when	when	SCONJ
bjos-8668749	179	2	the	the	DET
bjos-8668749	179	3	extracellular	extracellular	ADJ
bjos-8668749	179	4	portion	portion	NOUN
bjos-8668749	179	5	unfolds	unfold	VERB
bjos-8668749	179	6	,	,	PUNCT
bjos-8668749	179	7	the	the	DET
bjos-8668749	179	8	contact	contact	NOUN
bjos-8668749	179	9	is	be	AUX
bjos-8668749	179	10	broken	break	VERB
bjos-8668749	179	11	,	,	PUNCT
bjos-8668749	179	12	the	the	DET
bjos-8668749	179	13	intracellular	intracellular	ADJ
bjos-8668749	179	14	portions	portion	NOUN
bjos-8668749	179	15	separate	separate	ADJ
bjos-8668749	179	16	,	,	PUNCT
bjos-8668749	179	17	and	and	CCONJ
bjos-8668749	179	18	the	the	DET
bjos-8668749	179	19	talin	talin	NOUN
bjos-8668749	179	20	-	-	PUNCT
bjos-8668749	179	21	binding	bind	VERB
bjos-8668749	179	22	site	site	NOUN
bjos-8668749	179	23	on	on	ADP
bjos-8668749	179	24	the	the	DET
bjos-8668749	179	25	β	β	NOUN
bjos-8668749	179	26	-	-	NOUN
bjos-8668749	179	27	chain	chain	NOUN
bjos-8668749	179	28	is	be	AUX
bjos-8668749	179	29	exposed33,34	exposed33,34	PROPN
bjos-8668749	179	30	.	.	PUNCT
bjos-8668749	180	1	similarly	similarly	ADV
bjos-8668749	180	2	,	,	PUNCT
bjos-8668749	180	3	internal	internal	ADJ
bjos-8668749	180	4	conformational	conformational	ADJ
bjos-8668749	180	5	changes	change	NOUN
bjos-8668749	180	6	can	can	AUX
bjos-8668749	180	7	trigger	trigger	VERB
bjos-8668749	180	8	activation	activation	NOUN
bjos-8668749	180	9	of	of	ADP
bjos-8668749	180	10	the	the	DET
bjos-8668749	180	11	extracellular	extracellular	ADJ
bjos-8668749	180	12	integrin	integrin	NOUN
bjos-8668749	180	13	portion	portion	NOUN
bjos-8668749	180	14	.	.	PUNCT
bjos-8668749	181	1	talin	talin	NOUN
bjos-8668749	181	2	competes	compete	VERB
bjos-8668749	181	3	with	with	ADP
bjos-8668749	181	4	the	the	DET
bjos-8668749	181	5	α	α	NOUN
bjos-8668749	181	6	-	-	NOUN
bjos-8668749	181	7	chain	chain	NOUN
bjos-8668749	181	8	for	for	ADP
bjos-8668749	181	9	its	its	PRON
bjos-8668749	181	10	binding	bind	VERB
bjos-8668749	181	11	site	site	NOUN
bjos-8668749	181	12	on	on	ADP
bjos-8668749	181	13	the	the	DET
bjos-8668749	181	14	β	β	NOUN
bjos-8668749	181	15	-	-	NOUN
bjos-8668749	181	16	chain	chain	NOUN
bjos-8668749	181	17	.	.	PUNCT
bjos-8668749	182	1	when	when	SCONJ
bjos-8668749	182	2	talin	talin	NOUN
bjos-8668749	182	3	binds	bind	VERB
bjos-8668749	182	4	to	to	ADP
bjos-8668749	182	5	the	the	DET
bjos-8668749	182	6	β	β	NOUN
bjos-8668749	182	7	-	-	NOUN
bjos-8668749	182	8	chain	chain	NOUN
bjos-8668749	182	9	,	,	PUNCT
bjos-8668749	182	10	it	it	PRON
bjos-8668749	182	11	undoes	undo	VERB
bjos-8668749	182	12	the	the	DET
bjos-8668749	182	13	bond	bond	NOUN
bjos-8668749	182	14	between	between	ADP
bjos-8668749	182	15	the	the	DET
bjos-8668749	182	16	intracellular	intracellular	ADJ
bjos-8668749	182	17	tails	tail	NOUN
bjos-8668749	182	18	,	,	PUNCT
bjos-8668749	182	19	separating	separate	VERB
bjos-8668749	182	20	them	they	PRON
bjos-8668749	182	21	,	,	PUNCT
bjos-8668749	182	22	which	which	PRON
bjos-8668749	182	23	causes	cause	VERB
bjos-8668749	182	24	the	the	DET
bjos-8668749	182	25	extracellular	extracellular	ADJ
bjos-8668749	182	26	portion	portion	NOUN
bjos-8668749	182	27	of	of	ADP
bjos-8668749	182	28	the	the	DET
bjos-8668749	182	29	integrin	integrin	NOUN
bjos-8668749	182	30	to	to	PART
bjos-8668749	182	31	acquire	acquire	VERB
bjos-8668749	182	32	its	its	PRON
bjos-8668749	182	33	active	active	ADJ
bjos-8668749	182	34	conformation35	conformation35	NOUN
bjos-8668749	182	35	.	.	PUNCT
bjos-8668749	183	1	the	the	DET
bjos-8668749	183	2	binding	binding	NOUN
bjos-8668749	183	3	of	of	ADP
bjos-8668749	183	4	integrins	integrin	NOUN
bjos-8668749	183	5	to	to	ADP
bjos-8668749	183	6	their	their	PRON
bjos-8668749	183	7	ligands	ligand	NOUN
bjos-8668749	183	8	is	be	AUX
bjos-8668749	183	9	also	also	ADV
bjos-8668749	183	10	influenced	influence	VERB
bjos-8668749	183	11	by	by	ADP
bjos-8668749	183	12	the	the	DET
bjos-8668749	183	13	concentration	concentration	NOUN
bjos-8668749	183	14	in	in	ADP
bjos-8668749	183	15	the	the	DET
bjos-8668749	183	16	extracellular	extracellular	ADJ
bjos-8668749	183	17	medium	medium	NOUN
bjos-8668749	183	18	of	of	ADP
bjos-8668749	183	19	divalent	divalent	ADJ
bjos-8668749	183	20	cations	cation	NOUN
bjos-8668749	183	21	,	,	PUNCT
bjos-8668749	183	22	such	such	ADJ
bjos-8668749	183	23	as	as	ADP
bjos-8668749	183	24	ca+2	ca+2	PROPN
bjos-8668749	183	25	and	and	CCONJ
bjos-8668749	183	26	mg+2	mg+2	NOUN
bjos-8668749	183	27	,	,	PUNCT
bjos-8668749	183	28	which	which	PRON
bjos-8668749	183	29	can	can	AUX
bjos-8668749	183	30	act	act	VERB
bjos-8668749	183	31	in	in	ADP
bjos-8668749	183	32	different	different	ADJ
bjos-8668749	183	33	ways	way	NOUN
bjos-8668749	183	34	such	such	ADJ
bjos-8668749	183	35	as	as	ADP
bjos-8668749	183	36	promoting	promote	VERB
bjos-8668749	183	37	binding	bind	VERB
bjos-8668749	183	38	to	to	ADP
bjos-8668749	183	39	the	the	DET
bjos-8668749	183	40	ligand	ligand	NOUN
bjos-8668749	183	41	,	,	PUNCT
bjos-8668749	183	42	inhibiting	inhibit	VERB
bjos-8668749	183	43	binding	bind	VERB
bjos-8668749	183	44	to	to	ADP
bjos-8668749	183	45	the	the	DET
bjos-8668749	183	46	ligand	ligand	NOUN
bjos-8668749	183	47	,	,	PUNCT
bjos-8668749	183	48	and	and	CCONJ
bjos-8668749	183	49	altering	alter	VERB
bjos-8668749	183	50	the	the	DET
bjos-8668749	183	51	specificity	specificity	NOUN
bjos-8668749	183	52	and	and	CCONJ
bjos-8668749	183	53	binding	bind	VERB
bjos-8668749	183	54	to	to	ADP
bjos-8668749	183	55	the	the	DET
bjos-8668749	183	56	ligand36	ligand36	NOUN
bjos-8668749	183	57	.	.	PUNCT
bjos-8668749	184	1	integrin	integrin	NOUN
bjos-8668749	184	2	-	-	PUNCT
bjos-8668749	184	3	mediated	mediate	VERB
bjos-8668749	184	4	cell	cell	NOUN
bjos-8668749	184	5	adhesions	adhesion	NOUN
bjos-8668749	184	6	are	be	AUX
bjos-8668749	184	7	multiprotein	multiprotein	ADJ
bjos-8668749	184	8	complexes	complex	NOUN
bjos-8668749	184	9	that	that	PRON
bjos-8668749	184	10	bind	bind	VERB
bjos-8668749	184	11	the	the	DET
bjos-8668749	184	12	extracellular	extracellular	ADJ
bjos-8668749	184	13	matrix	matrix	NOUN
bjos-8668749	184	14	to	to	ADP
bjos-8668749	184	15	the	the	DET
bjos-8668749	184	16	cytoskeleton	cytoskeleton	NOUN
bjos-8668749	184	17	.	.	PUNCT
bjos-8668749	185	1	the	the	DET
bjos-8668749	185	2	adhesions	adhesion	NOUN
bjos-8668749	185	3	can	can	AUX
bjos-8668749	185	4	involve	involve	VERB
bjos-8668749	185	5	about	about	ADV
bjos-8668749	185	6	200	200	NUM
bjos-8668749	185	7	components	component	NOUN
bjos-8668749	185	8	,	,	PUNCT
bjos-8668749	185	9	which	which	PRON
bjos-8668749	185	10	are	be	AUX
bjos-8668749	185	11	associated	associate	VERB
bjos-8668749	185	12	with	with	ADP
bjos-8668749	185	13	distinct	distinct	ADJ
bjos-8668749	185	14	functions	function	NOUN
bjos-8668749	185	15	,	,	PUNCT
bjos-8668749	185	16	including	include	VERB
bjos-8668749	185	17	actin	actin	NOUN
bjos-8668749	185	18	regulators	regulator	NOUN
bjos-8668749	185	19	,	,	PUNCT
bjos-8668749	185	20	adaptor	adaptor	NOUN
bjos-8668749	185	21	proteins	protein	NOUN
bjos-8668749	185	22	that	that	PRON
bjos-8668749	185	23	directly	directly	ADV
bjos-8668749	185	24	or	or	CCONJ
bjos-8668749	185	25	indirectly	indirectly	ADV
bjos-8668749	185	26	bind	bind	VERB
bjos-8668749	185	27	actin	actin	NOUN
bjos-8668749	185	28	to	to	ADP
bjos-8668749	185	29	integrins	integrin	NOUN
bjos-8668749	185	30	,	,	PUNCT
bjos-8668749	185	31	and	and	CCONJ
bjos-8668749	185	32	a	a	DET
bjos-8668749	185	33	variety	variety	NOUN
bjos-8668749	185	34	of	of	ADP
bjos-8668749	185	35	signaling	signal	VERB
bjos-8668749	185	36	molecules	molecule	NOUN
bjos-8668749	185	37	,	,	PUNCT
bjos-8668749	185	38	such	such	ADJ
bjos-8668749	185	39	as	as	ADP
bjos-8668749	185	40	kinases	kinase	NOUN
bjos-8668749	185	41	,	,	PUNCT
bjos-8668749	185	42	phosphatases	phosphatase	NOUN
bjos-8668749	185	43	,	,	PUNCT
bjos-8668749	185	44	and	and	CCONJ
bjos-8668749	185	45	g	g	NOUN
bjos-8668749	185	46	proteins	protein	NOUN
bjos-8668749	185	47	and	and	CCONJ
bjos-8668749	185	48	their	their	PRON
bjos-8668749	185	49	regulators	regulator	NOUN
bjos-8668749	185	50	.	.	PUNCT
bjos-8668749	186	1	integrin	integrin	NOUN
bjos-8668749	186	2	-	-	PUNCT
bjos-8668749	186	3	mediated	mediate	VERB
bjos-8668749	186	4	cell	cell	NOUN
bjos-8668749	186	5	-	-	PUNCT
bjos-8668749	186	6	extracellular	extracellular	ADJ
bjos-8668749	186	7	matrix	matrix	NOUN
bjos-8668749	186	8	adhesion	adhesion	NOUN
bjos-8668749	186	9	complexes	complex	NOUN
bjos-8668749	186	10	include	include	VERB
bjos-8668749	186	11	focal	focal	ADJ
bjos-8668749	186	12	complex	complex	ADJ
bjos-8668749	186	13	,	,	PUNCT
bjos-8668749	186	14	focal	focal	ADJ
bjos-8668749	186	15	adhesion	adhesion	NOUN
bjos-8668749	186	16	,	,	PUNCT
bjos-8668749	186	17	and	and	CCONJ
bjos-8668749	186	18	fibrillar	fibrillar	ADJ
bjos-8668749	186	19	adhesion37	adhesion37	NOUN
bjos-8668749	186	20	.	.	PUNCT
bjos-8668749	187	1	10	10	NUM
bjos-8668749	187	2	nascimento	nascimento	PROPN
bjos-8668749	187	3	et	et	PROPN
bjos-8668749	187	4	al	al	PROPN
bjos-8668749	187	5	.	.	PROPN
bjos-8668749	188	1	braz	braz	PROPN
bjos-8668749	188	2	j	j	PROPN
bjos-8668749	188	3	oral	oral	PROPN
bjos-8668749	188	4	sci	sci	PROPN
bjos-8668749	188	5	.	.	PUNCT
bjos-8668749	189	1	2023;22	2023;22	NUM
bjos-8668749	189	2	:	:	PUNCT
bjos-8668749	189	3	e238749	e238749	PROPN
bjos-8668749	189	4	discussion	discussion	NOUN
bjos-8668749	189	5	the	the	DET
bjos-8668749	189	6	osseointegration	osseointegration	NOUN
bjos-8668749	189	7	concept	concept	NOUN
bjos-8668749	189	8	proposes	propose	VERB
bjos-8668749	189	9	the	the	DET
bjos-8668749	189	10	idea	idea	NOUN
bjos-8668749	189	11	of	of	ADP
bjos-8668749	189	12	bone	bone	NOUN
bjos-8668749	189	13	regeneration	regeneration	NOUN
bjos-8668749	189	14	,	,	PUNCT
bjos-8668749	189	15	where	where	SCONJ
bjos-8668749	189	16	the	the	DET
bjos-8668749	189	17	tissues	tissue	NOUN
bjos-8668749	189	18	are	be	AUX
bjos-8668749	189	19	anchored	anchor	VERB
bjos-8668749	189	20	by	by	ADP
bjos-8668749	189	21	proteins	protein	NOUN
bjos-8668749	189	22	on	on	ADP
bjos-8668749	189	23	the	the	DET
bjos-8668749	189	24	implant	implant	ADJ
bjos-8668749	189	25	surface38	surface38	ADJ
bjos-8668749	189	26	.	.	PUNCT
bjos-8668749	190	1	davies13	davies13	NOUN
bjos-8668749	190	2	(	(	PUNCT
bjos-8668749	190	3	2007	2007	NUM
bjos-8668749	190	4	)	)	PUNCT
bjos-8668749	190	5	considers	consider	VERB
bjos-8668749	190	6	it	it	PRON
bjos-8668749	190	7	important	important	ADJ
bjos-8668749	190	8	to	to	PART
bjos-8668749	190	9	understand	understand	VERB
bjos-8668749	190	10	the	the	DET
bjos-8668749	190	11	cellular	cellular	ADJ
bjos-8668749	190	12	mechanisms	mechanism	NOUN
bjos-8668749	190	13	involved	involve	VERB
bjos-8668749	190	14	in	in	ADP
bjos-8668749	190	15	bone	bone	NOUN
bjos-8668749	190	16	regeneration	regeneration	NOUN
bjos-8668749	190	17	and	and	CCONJ
bjos-8668749	190	18	remodeling	remodeling	NOUN
bjos-8668749	190	19	during	during	ADP
bjos-8668749	190	20	the	the	DET
bjos-8668749	190	21	planning	planning	NOUN
bjos-8668749	190	22	and	and	CCONJ
bjos-8668749	190	23	selection	selection	NOUN
bjos-8668749	190	24	of	of	ADP
bjos-8668749	190	25	the	the	DET
bjos-8668749	190	26	surgical	surgical	ADJ
bjos-8668749	190	27	technique	technique	NOUN
bjos-8668749	190	28	for	for	ADP
bjos-8668749	190	29	installing	instal	VERB
bjos-8668749	190	30	osseointegrable	osseointegrable	ADJ
bjos-8668749	190	31	implants	implant	NOUN
bjos-8668749	190	32	.	.	PUNCT
bjos-8668749	191	1	according	accord	VERB
bjos-8668749	191	2	to	to	ADP
bjos-8668749	191	3	mendes	mende	NOUN
bjos-8668749	191	4	and	and	CCONJ
bjos-8668749	191	5	davies4	davies4	PROPN
bjos-8668749	191	6	(	(	PUNCT
bjos-8668749	191	7	2016	2016	NUM
bjos-8668749	191	8	)	)	PUNCT
bjos-8668749	191	9	,	,	PUNCT
bjos-8668749	191	10	there	there	PRON
bjos-8668749	191	11	is	be	VERB
bjos-8668749	191	12	no	no	DET
bjos-8668749	191	13	direct	direct	ADJ
bjos-8668749	191	14	bone	bone	NOUN
bjos-8668749	191	15	connection	connection	NOUN
bjos-8668749	191	16	with	with	ADP
bjos-8668749	191	17	the	the	DET
bjos-8668749	191	18	implant	implant	ADJ
bjos-8668749	191	19	surface	surface	NOUN
bjos-8668749	191	20	,	,	PUNCT
bjos-8668749	191	21	as	as	SCONJ
bjos-8668749	191	22	was	be	AUX
bjos-8668749	191	23	previously	previously	ADV
bjos-8668749	191	24	believed	believe	VERB
bjos-8668749	191	25	.	.	PUNCT
bjos-8668749	192	1	after	after	ADP
bjos-8668749	192	2	implant	implant	ADJ
bjos-8668749	192	3	installation	installation	NOUN
bjos-8668749	192	4	,	,	PUNCT
bjos-8668749	192	5	an	an	DET
bjos-8668749	192	6	adsorption	adsorption	NOUN
bjos-8668749	192	7	of	of	ADP
bjos-8668749	192	8	blood	blood	NOUN
bjos-8668749	192	9	plasma	plasma	NOUN
bjos-8668749	192	10	proteins	protein	NOUN
bjos-8668749	192	11	occurs	occur	VERB
bjos-8668749	192	12	followed	follow	VERB
bjos-8668749	192	13	by	by	ADP
bjos-8668749	192	14	differentiation	differentiation	NOUN
bjos-8668749	192	15	and	and	CCONJ
bjos-8668749	192	16	production	production	NOUN
bjos-8668749	192	17	of	of	ADP
bjos-8668749	192	18	the	the	DET
bjos-8668749	192	19	bone	bone	NOUN
bjos-8668749	192	20	matrix	matrix	NOUN
bjos-8668749	192	21	at	at	ADP
bjos-8668749	192	22	the	the	DET
bjos-8668749	192	23	interface	interface	NOUN
bjos-8668749	192	24	with	with	ADP
bjos-8668749	192	25	the	the	DET
bjos-8668749	192	26	implant	implant	ADJ
bjos-8668749	192	27	surface	surface	NOUN
bjos-8668749	192	28	.	.	PUNCT
bjos-8668749	193	1	in	in	ADP
bjos-8668749	193	2	this	this	DET
bjos-8668749	193	3	process	process	NOUN
bjos-8668749	193	4	,	,	PUNCT
bjos-8668749	193	5	integrin	integrin	NOUN
bjos-8668749	193	6	,	,	PUNCT
bjos-8668749	193	7	a	a	DET
bjos-8668749	193	8	plasma	plasma	NOUN
bjos-8668749	193	9	membrane	membrane	NOUN
bjos-8668749	193	10	glycoprotein	glycoprotein	NOUN
bjos-8668749	193	11	,	,	PUNCT
bjos-8668749	193	12	acts	act	VERB
bjos-8668749	193	13	to	to	PART
bjos-8668749	193	14	control	control	VERB
bjos-8668749	193	15	cell	cell	NOUN
bjos-8668749	193	16	response	response	NOUN
bjos-8668749	193	17	and	and	CCONJ
bjos-8668749	193	18	biological	biological	ADJ
bjos-8668749	193	19	interaction	interaction	NOUN
bjos-8668749	193	20	with	with	ADP
bjos-8668749	193	21	implants25	implants25	NOUN
bjos-8668749	193	22	.	.	PUNCT
bjos-8668749	194	1	in	in	ADP
bjos-8668749	194	2	this	this	DET
bjos-8668749	194	3	sense	sense	NOUN
bjos-8668749	194	4	,	,	PUNCT
bjos-8668749	194	5	the	the	DET
bjos-8668749	194	6	initial	initial	ADJ
bjos-8668749	194	7	phase	phase	NOUN
bjos-8668749	194	8	of	of	ADP
bjos-8668749	194	9	protein	protein	NOUN
bjos-8668749	194	10	adsorption	adsorption	NOUN
bjos-8668749	194	11	and	and	CCONJ
bjos-8668749	194	12	desorption	desorption	NOUN
bjos-8668749	194	13	will	will	AUX
bjos-8668749	194	14	be	be	AUX
bjos-8668749	194	15	described	describe	VERB
bjos-8668749	194	16	by	by	ADP
bjos-8668749	194	17	the	the	DET
bjos-8668749	194	18	vroman	vroman	NOUN
bjos-8668749	194	19	effect	effect	NOUN
bjos-8668749	194	20	.	.	PUNCT
bjos-8668749	195	1	in	in	ADP
bjos-8668749	195	2	which	which	PRON
bjos-8668749	195	3	proteins	protein	NOUN
bjos-8668749	195	4	with	with	ADP
bjos-8668749	195	5	high	high	ADJ
bjos-8668749	195	6	mobility	mobility	NOUN
bjos-8668749	195	7	and	and	CCONJ
bjos-8668749	195	8	concentration	concentration	NOUN
bjos-8668749	195	9	,	,	PUNCT
bjos-8668749	195	10	such	such	ADJ
bjos-8668749	195	11	as	as	ADP
bjos-8668749	195	12	albumin	albumin	NOUN
bjos-8668749	195	13	(	(	PUNCT
bjos-8668749	195	14	40mg	40mg	NOUN
bjos-8668749	195	15	/	/	SYM
bjos-8668749	195	16	ml	ml	ADJ
bjos-8668749	195	17	,	,	PUNCT
bjos-8668749	195	18	molecular	molecular	ADJ
bjos-8668749	195	19	weight	weight	NOUN
bjos-8668749	195	20	67kda	67kda	NOUN
bjos-8668749	195	21	and	and	CCONJ
bjos-8668749	195	22	diffusion	diffusion	NOUN
bjos-8668749	195	23	coefficient	coefficient	NOUN
bjos-8668749	195	24	6.1x10	6.1x10	NOUN
bjos-8668749	195	25	-	-	PROPN
bjos-8668749	195	26	7cm2	7cm2	NUM
bjos-8668749	195	27	/	/	SYM
bjos-8668749	195	28	s	s	NOUN
bjos-8668749	195	29	)	)	PUNCT
bjos-8668749	195	30	,	,	PUNCT
bjos-8668749	195	31	are	be	AUX
bjos-8668749	195	32	the	the	DET
bjos-8668749	195	33	first	first	ADJ
bjos-8668749	195	34	to	to	PART
bjos-8668749	195	35	be	be	AUX
bjos-8668749	195	36	adsorbed	adsorb	VERB
bjos-8668749	195	37	after	after	ADP
bjos-8668749	195	38	implant	implant	ADJ
bjos-8668749	195	39	insertion	insertion	NOUN
bjos-8668749	195	40	and	and	CCONJ
bjos-8668749	195	41	over	over	ADP
bjos-8668749	195	42	time	time	NOUN
bjos-8668749	195	43	are	be	AUX
bjos-8668749	195	44	replaced	replace	VERB
bjos-8668749	195	45	by	by	ADP
bjos-8668749	195	46	other	other	ADJ
bjos-8668749	195	47	proteins	protein	NOUN
bjos-8668749	195	48	such	such	ADJ
bjos-8668749	195	49	as	as	ADP
bjos-8668749	195	50	fibrinogen	fibrinogen	NOUN
bjos-8668749	195	51	(	(	PUNCT
bjos-8668749	195	52	3mg	3mg	NOUN
bjos-8668749	195	53	/	/	SYM
bjos-8668749	195	54	ml	ml	NOUN
bjos-8668749	195	55	,	,	PUNCT
bjos-8668749	195	56	molecular	molecular	ADJ
bjos-8668749	195	57	weight	weight	NOUN
bjos-8668749	195	58	340kda	340kda	NUM
bjos-8668749	195	59	and	and	CCONJ
bjos-8668749	195	60	diffusion	diffusion	NOUN
bjos-8668749	195	61	coefficient	coefficient	NOUN
bjos-8668749	195	62	2.0x10	2.0x10	NUM
bjos-8668749	195	63	-	-	PROPN
bjos-8668749	195	64	7cm2	7cm2	NUM
bjos-8668749	195	65	/	/	SYM
bjos-8668749	195	66	s	s	NOUN
bjos-8668749	195	67	)	)	PUNCT
bjos-8668749	195	68	.	.	PUNCT
bjos-8668749	196	1	the	the	DET
bjos-8668749	196	2	whole	whole	ADJ
bjos-8668749	196	3	anchoring	anchoring	NOUN
bjos-8668749	196	4	process	process	NOUN
bjos-8668749	196	5	is	be	AUX
bjos-8668749	196	6	influenced	influence	VERB
bjos-8668749	196	7	by	by	ADP
bjos-8668749	196	8	the	the	DET
bjos-8668749	196	9	implant	implant	ADJ
bjos-8668749	196	10	surface	surface	NOUN
bjos-8668749	196	11	characteristics1	characteristics1	NOUN
bjos-8668749	196	12	.	.	PUNCT
bjos-8668749	197	1	kumar	kumar	PROPN
bjos-8668749	197	2	et	et	PROPN
bjos-8668749	197	3	al.39	al.39	PROPN
bjos-8668749	197	4	(	(	PUNCT
bjos-8668749	197	5	2004	2004	NUM
bjos-8668749	197	6	)	)	PUNCT
bjos-8668749	197	7	states	state	VERB
bjos-8668749	197	8	that	that	SCONJ
bjos-8668749	197	9	still	still	ADV
bjos-8668749	197	10	in	in	ADP
bjos-8668749	197	11	the	the	DET
bjos-8668749	197	12	initial	initial	ADJ
bjos-8668749	197	13	phase	phase	NOUN
bjos-8668749	197	14	of	of	ADP
bjos-8668749	197	15	osseointegration	osseointegration	NOUN
bjos-8668749	197	16	,	,	PUNCT
bjos-8668749	197	17	thrombin	thrombin	NOUN
bjos-8668749	197	18	and	and	CCONJ
bjos-8668749	197	19	fibrinogen	fibrinogen	NOUN
bjos-8668749	197	20	adhere	adhere	NOUN
bjos-8668749	197	21	to	to	ADP
bjos-8668749	197	22	the	the	DET
bjos-8668749	197	23	implant	implant	ADJ
bjos-8668749	197	24	surface	surface	NOUN
bjos-8668749	197	25	,	,	PUNCT
bjos-8668749	197	26	subsequently	subsequently	ADV
bjos-8668749	197	27	,	,	PUNCT
bjos-8668749	197	28	neutrophils	neutrophil	NOUN
bjos-8668749	197	29	populate	populate	VERB
bjos-8668749	197	30	the	the	DET
bjos-8668749	197	31	implant	implant	ADJ
bjos-8668749	197	32	receptor	receptor	NOUN
bjos-8668749	197	33	site	site	NOUN
bjos-8668749	197	34	before	before	ADP
bjos-8668749	197	35	monocytes	monocyte	NOUN
bjos-8668749	197	36	and	and	CCONJ
bjos-8668749	197	37	macrophages	macrophage	NOUN
bjos-8668749	197	38	infiltrate	infiltrate	VERB
bjos-8668749	197	39	the	the	DET
bjos-8668749	197	40	area	area	NOUN
bjos-8668749	197	41	.	.	PUNCT
bjos-8668749	198	1	and	and	CCONJ
bjos-8668749	198	2	only	only	ADV
bjos-8668749	198	3	five	five	NUM
bjos-8668749	198	4	days	day	NOUN
bjos-8668749	198	5	after	after	ADP
bjos-8668749	198	6	implantation	implantation	NOUN
bjos-8668749	198	7	,	,	PUNCT
bjos-8668749	198	8	newly	newly	ADV
bjos-8668749	198	9	formed	form	VERB
bjos-8668749	198	10	bone	bone	NOUN
bjos-8668749	198	11	tissue	tissue	NOUN
bjos-8668749	198	12	is	be	AUX
bjos-8668749	198	13	already	already	ADV
bjos-8668749	198	14	present	present	ADJ
bjos-8668749	198	15	.	.	PUNCT
bjos-8668749	199	1	in	in	ADP
bjos-8668749	199	2	about	about	ADV
bjos-8668749	199	3	eight	eight	NUM
bjos-8668749	199	4	to	to	PART
bjos-8668749	199	5	twelve	twelve	NUM
bjos-8668749	199	6	weeks	week	NOUN
bjos-8668749	199	7	,	,	PUNCT
bjos-8668749	199	8	osseointegration	osseointegration	NOUN
bjos-8668749	199	9	occurs	occur	VERB
bjos-8668749	199	10	.	.	PUNCT
bjos-8668749	200	1	furthermore	furthermore	ADV
bjos-8668749	200	2	,	,	PUNCT
bjos-8668749	200	3	according	accord	VERB
bjos-8668749	200	4	to	to	ADP
bjos-8668749	200	5	nascimento38	nascimento38	PROPN
bjos-8668749	200	6	(	(	PUNCT
bjos-8668749	200	7	2022	2022	NUM
bjos-8668749	200	8	)	)	PUNCT
bjos-8668749	200	9	protein	protein	NOUN
bjos-8668749	200	10	adsorption	adsorption	NOUN
bjos-8668749	200	11	on	on	ADP
bjos-8668749	200	12	the	the	DET
bjos-8668749	200	13	implant	implant	ADJ
bjos-8668749	200	14	surface	surface	NOUN
bjos-8668749	200	15	creates	create	VERB
bjos-8668749	200	16	a	a	DET
bjos-8668749	200	17	cell	cell	NOUN
bjos-8668749	200	18	-	-	PUNCT
bjos-8668749	200	19	implant	implant	ADJ
bjos-8668749	200	20	layer	layer	NOUN
bjos-8668749	200	21	,	,	PUNCT
bjos-8668749	200	22	characterizing	characterize	VERB
bjos-8668749	200	23	a	a	DET
bjos-8668749	200	24	sequence	sequence	NOUN
bjos-8668749	200	25	of	of	ADP
bjos-8668749	200	26	protein	protein	NOUN
bjos-8668749	200	27	anchors	anchor	NOUN
bjos-8668749	200	28	around	around	ADP
bjos-8668749	200	29	of	of	ADP
bjos-8668749	200	30	the	the	DET
bjos-8668749	200	31	dental	dental	ADJ
bjos-8668749	200	32	implant	implant	NOUN
bjos-8668749	200	33	,	,	PUNCT
bjos-8668749	200	34	providing	provide	VERB
bjos-8668749	200	35	an	an	DET
bjos-8668749	200	36	osteoconductive	osteoconductive	ADJ
bjos-8668749	200	37	space	space	NOUN
bjos-8668749	200	38	that	that	PRON
bjos-8668749	200	39	will	will	AUX
bjos-8668749	200	40	subsidize	subsidize	VERB
bjos-8668749	200	41	the	the	DET
bjos-8668749	200	42	osteoconductive	osteoconductive	ADJ
bjos-8668749	200	43	ligament	ligament	NOUN
bjos-8668749	200	44	to	to	PART
bjos-8668749	200	45	form	form	VERB
bjos-8668749	200	46	the	the	DET
bjos-8668749	200	47	peri	peri	NOUN
bjos-8668749	200	48	-	-	PUNCT
bjos-8668749	200	49	implant	implant	ADJ
bjos-8668749	200	50	ligament	ligament	NOUN
bjos-8668749	200	51	.	.	PUNCT
bjos-8668749	201	1	these	these	DET
bjos-8668749	201	2	proteins	protein	NOUN
bjos-8668749	201	3	facilitate	facilitate	VERB
bjos-8668749	201	4	and	and	CCONJ
bjos-8668749	201	5	regulate	regulate	VERB
bjos-8668749	201	6	cellular	cellular	ADJ
bjos-8668749	201	7	events	event	NOUN
bjos-8668749	201	8	for	for	ADP
bjos-8668749	201	9	tissue	tissue	NOUN
bjos-8668749	201	10	regeneration	regeneration	NOUN
bjos-8668749	201	11	,	,	PUNCT
bjos-8668749	201	12	so	so	SCONJ
bjos-8668749	201	13	the	the	DET
bjos-8668749	201	14	properties	property	NOUN
bjos-8668749	201	15	of	of	ADP
bjos-8668749	201	16	the	the	DET
bjos-8668749	201	17	biomaterial	biomaterial	ADJ
bjos-8668749	201	18	surface	surface	NOUN
bjos-8668749	201	19	,	,	PUNCT
bjos-8668749	201	20	especially	especially	ADV
bjos-8668749	201	21	the	the	DET
bjos-8668749	201	22	roughness	roughness	NOUN
bjos-8668749	201	23	,	,	PUNCT
bjos-8668749	201	24	influence	influence	VERB
bjos-8668749	201	25	the	the	DET
bjos-8668749	201	26	amount	amount	NOUN
bjos-8668749	201	27	and	and	CCONJ
bjos-8668749	201	28	properties	property	NOUN
bjos-8668749	201	29	of	of	ADP
bjos-8668749	201	30	the	the	DET
bjos-8668749	201	31	proteins1	proteins1	NOUN
bjos-8668749	201	32	.	.	PUNCT
bjos-8668749	202	1	kastantin	kastantin	PROPN
bjos-8668749	202	2	et	et	PROPN
bjos-8668749	202	3	al.40	al.40	PROPN
bjos-8668749	202	4	(	(	PUNCT
bjos-8668749	202	5	2014	2014	NUM
bjos-8668749	202	6	)	)	PUNCT
bjos-8668749	202	7	highlights	highlight	NOUN
bjos-8668749	202	8	that	that	SCONJ
bjos-8668749	202	9	the	the	DET
bjos-8668749	202	10	biomaterial	biomaterial	ADJ
bjos-8668749	202	11	physicochemical	physicochemical	ADJ
bjos-8668749	202	12	properties	property	NOUN
bjos-8668749	202	13	,	,	PUNCT
bjos-8668749	202	14	such	such	ADJ
bjos-8668749	202	15	as	as	ADP
bjos-8668749	202	16	ph	ph	ADJ
bjos-8668749	202	17	,	,	PUNCT
bjos-8668749	202	18	temperature	temperature	NOUN
bjos-8668749	202	19	,	,	PUNCT
bjos-8668749	202	20	surrounding	surround	VERB
bjos-8668749	202	21	solvent	solvent	ADJ
bjos-8668749	202	22	system	system	NOUN
bjos-8668749	202	23	,	,	PUNCT
bjos-8668749	202	24	ionic	ionic	ADJ
bjos-8668749	202	25	strengths	strength	NOUN
bjos-8668749	202	26	,	,	PUNCT
bjos-8668749	202	27	different	different	ADJ
bjos-8668749	202	28	protein	protein	NOUN
bjos-8668749	202	29	concentrations	concentration	NOUN
bjos-8668749	202	30	or	or	CCONJ
bjos-8668749	202	31	even	even	ADV
bjos-8668749	202	32	the	the	DET
bjos-8668749	202	33	size	size	NOUN
bjos-8668749	202	34	and	and	CCONJ
bjos-8668749	202	35	structure	structure	NOUN
bjos-8668749	202	36	of	of	ADP
bjos-8668749	202	37	these	these	DET
bjos-8668749	202	38	proteins	protein	NOUN
bjos-8668749	202	39	affect	affect	VERB
bjos-8668749	202	40	the	the	DET
bjos-8668749	202	41	adsorption	adsorption	NOUN
bjos-8668749	202	42	behavior	behavior	NOUN
bjos-8668749	202	43	of	of	ADP
bjos-8668749	202	44	proteins	protein	NOUN
bjos-8668749	202	45	.	.	PUNCT
bjos-8668749	203	1	this	this	DET
bjos-8668749	203	2	adsorption	adsorption	NOUN
bjos-8668749	203	3	occurs	occur	VERB
bjos-8668749	203	4	in	in	ADP
bjos-8668749	203	5	monolayer	monolayer	NOUN
bjos-8668749	203	6	and	and	CCONJ
bjos-8668749	203	7	not	not	PART
bjos-8668749	203	8	by	by	ADP
bjos-8668749	203	9	stacking	stack	VERB
bjos-8668749	203	10	,	,	PUNCT
bjos-8668749	203	11	within	within	ADP
bjos-8668749	203	12	a	a	DET
bjos-8668749	203	13	few	few	ADJ
bjos-8668749	203	14	seconds	second	NOUN
bjos-8668749	203	15	from	from	ADP
bjos-8668749	203	16	the	the	DET
bjos-8668749	203	17	biomaterial	biomaterial	ADJ
bjos-8668749	203	18	implantation	implantation	NOUN
bjos-8668749	203	19	.	.	PUNCT
bjos-8668749	204	1	cells	cell	NOUN
bjos-8668749	204	2	have	have	VERB
bjos-8668749	204	3	no	no	DET
bjos-8668749	204	4	direct	direct	ADJ
bjos-8668749	204	5	contact	contact	NOUN
bjos-8668749	204	6	with	with	ADP
bjos-8668749	204	7	the	the	DET
bjos-8668749	204	8	biomaterial	biomaterial	ADJ
bjos-8668749	204	9	surface	surface	NOUN
bjos-8668749	204	10	,	,	PUNCT
bjos-8668749	204	11	which	which	PRON
bjos-8668749	204	12	characterizes	characterize	VERB
bjos-8668749	204	13	the	the	DET
bjos-8668749	204	14	implant	implant	ADJ
bjos-8668749	204	15	body	body	NOUN
bjos-8668749	204	16	response	response	NOUN
bjos-8668749	204	17	by	by	ADP
bjos-8668749	204	18	the	the	DET
bjos-8668749	204	19	nature	nature	NOUN
bjos-8668749	204	20	of	of	ADP
bjos-8668749	204	21	protein	protein	NOUN
bjos-8668749	204	22	adsorption39,40	adsorption39,40	PROPN
bjos-8668749	204	23	.	.	PUNCT
bjos-8668749	205	1	the	the	DET
bjos-8668749	205	2	biomaterial	biomaterial	ADJ
bjos-8668749	205	3	surfaces	surface	NOUN
bjos-8668749	205	4	properties	property	NOUN
bjos-8668749	205	5	influence	influence	VERB
bjos-8668749	205	6	the	the	DET
bjos-8668749	205	7	binding	bind	VERB
bjos-8668749	205	8	interface	interface	NOUN
bjos-8668749	205	9	of	of	ADP
bjos-8668749	205	10	biomolecules	biomolecule	NOUN
bjos-8668749	205	11	.	.	PUNCT
bjos-8668749	206	1	morphology	morphology	NOUN
bjos-8668749	206	2	,	,	PUNCT
bjos-8668749	206	3	chemical	chemical	NOUN
bjos-8668749	206	4	composition	composition	NOUN
bjos-8668749	206	5	,	,	PUNCT
bjos-8668749	206	6	wettability	wettability	NOUN
bjos-8668749	206	7	,	,	PUNCT
bjos-8668749	206	8	homogeneity	homogeneity	NOUN
bjos-8668749	206	9	,	,	PUNCT
bjos-8668749	206	10	and	and	CCONJ
bjos-8668749	206	11	energy	energy	NOUN
bjos-8668749	206	12	are	be	AUX
bjos-8668749	206	13	the	the	DET
bjos-8668749	206	14	main	main	ADJ
bjos-8668749	206	15	surfaces	surface	NOUN
bjos-8668749	206	16	properties	property	NOUN
bjos-8668749	206	17	.	.	PUNCT
bjos-8668749	207	1	however	however	ADV
bjos-8668749	207	2	,	,	PUNCT
bjos-8668749	207	3	when	when	SCONJ
bjos-8668749	207	4	several	several	ADJ
bjos-8668749	207	5	proteins	protein	NOUN
bjos-8668749	207	6	simultaneously	simultaneously	ADV
bjos-8668749	207	7	come	come	VERB
bjos-8668749	207	8	into	into	ADP
bjos-8668749	207	9	contact	contact	NOUN
bjos-8668749	207	10	with	with	ADP
bjos-8668749	207	11	the	the	DET
bjos-8668749	207	12	surface	surface	NOUN
bjos-8668749	207	13	,	,	PUNCT
bjos-8668749	207	14	there	there	PRON
bjos-8668749	207	15	is	be	VERB
bjos-8668749	207	16	a	a	DET
bjos-8668749	207	17	competition	competition	NOUN
bjos-8668749	207	18	between	between	ADP
bjos-8668749	207	19	them	they	PRON
bjos-8668749	207	20	.	.	PUNCT
bjos-8668749	208	1	the	the	DET
bjos-8668749	208	2	proteins	protein	NOUN
bjos-8668749	208	3	properties	property	NOUN
bjos-8668749	208	4	11	11	NUM
bjos-8668749	208	5	nascimento	nascimento	PROPN
bjos-8668749	208	6	et	et	PROPN
bjos-8668749	208	7	al	al	PROPN
bjos-8668749	208	8	.	.	PROPN
bjos-8668749	209	1	braz	braz	PROPN
bjos-8668749	209	2	j	j	PROPN
bjos-8668749	209	3	oral	oral	PROPN
bjos-8668749	209	4	sci	sci	PROPN
bjos-8668749	209	5	.	.	PUNCT
bjos-8668749	210	1	2023;22	2023;22	NUM
bjos-8668749	210	2	:	:	PUNCT
bjos-8668749	210	3	e238749	e238749	NOUN
bjos-8668749	210	4	that	that	PRON
bjos-8668749	210	5	influence	influence	VERB
bjos-8668749	210	6	these	these	DET
bjos-8668749	210	7	interactions	interaction	NOUN
bjos-8668749	210	8	,	,	PUNCT
bjos-8668749	210	9	among	among	ADP
bjos-8668749	210	10	them	they	PRON
bjos-8668749	210	11	molecular	molecular	ADJ
bjos-8668749	210	12	weight	weight	NOUN
bjos-8668749	210	13	,	,	PUNCT
bjos-8668749	210	14	electrical	electrical	ADJ
bjos-8668749	210	15	charge	charge	NOUN
bjos-8668749	210	16	,	,	PUNCT
bjos-8668749	210	17	size	size	NOUN
bjos-8668749	210	18	,	,	PUNCT
bjos-8668749	210	19	structure	structure	NOUN
bjos-8668749	210	20	stability	stability	NOUN
bjos-8668749	210	21	,	,	PUNCT
bjos-8668749	210	22	and	and	CCONJ
bjos-8668749	210	23	unfolding	unfold	VERB
bjos-8668749	210	24	ability	ability	NOUN
bjos-8668749	210	25	,	,	PUNCT
bjos-8668749	210	26	are	be	AUX
bjos-8668749	210	27	important	important	ADJ
bjos-8668749	210	28	parameters	parameter	NOUN
bjos-8668749	210	29	.	.	PUNCT
bjos-8668749	211	1	due	due	ADP
bjos-8668749	211	2	to	to	ADP
bjos-8668749	211	3	the	the	DET
bjos-8668749	211	4	hydrophilicity	hydrophilicity	NOUN
bjos-8668749	211	5	,	,	PUNCT
bjos-8668749	211	6	the	the	DET
bjos-8668749	211	7	electrical	electrical	ADJ
bjos-8668749	211	8	charges	charge	NOUN
bjos-8668749	211	9	of	of	ADP
bjos-8668749	211	10	the	the	DET
bjos-8668749	211	11	amino	amino	ADJ
bjos-8668749	211	12	acids	acid	NOUN
bjos-8668749	211	13	are	be	AUX
bjos-8668749	211	14	on	on	ADP
bjos-8668749	211	15	the	the	DET
bjos-8668749	211	16	outside	outside	NOUN
bjos-8668749	211	17	of	of	ADP
bjos-8668749	211	18	the	the	DET
bjos-8668749	211	19	protein	protein	NOUN
bjos-8668749	211	20	.	.	PUNCT
bjos-8668749	212	1	proteins	protein	NOUN
bjos-8668749	212	2	with	with	ADP
bjos-8668749	212	3	a	a	DET
bjos-8668749	212	4	higher	high	ADJ
bjos-8668749	212	5	number	number	NOUN
bjos-8668749	212	6	of	of	ADP
bjos-8668749	212	7	charges	charge	NOUN
bjos-8668749	212	8	tend	tend	VERB
bjos-8668749	212	9	to	to	PART
bjos-8668749	212	10	have	have	VERB
bjos-8668749	212	11	a	a	DET
bjos-8668749	212	12	greater	great	ADJ
bjos-8668749	212	13	influence	influence	NOUN
bjos-8668749	212	14	on	on	ADP
bjos-8668749	212	15	adsorption	adsorption	NOUN
bjos-8668749	212	16	.	.	PUNCT
bjos-8668749	213	1	the	the	DET
bjos-8668749	213	2	unfolding	unfold	VERB
bjos-8668749	213	3	ability	ability	NOUN
bjos-8668749	213	4	also	also	ADV
bjos-8668749	213	5	influences	influence	VERB
bjos-8668749	213	6	the	the	DET
bjos-8668749	213	7	protein	protein	NOUN
bjos-8668749	213	8	adsorption	adsorption	NOUN
bjos-8668749	213	9	.	.	PUNCT
bjos-8668749	214	1	proteins	protein	NOUN
bjos-8668749	214	2	that	that	PRON
bjos-8668749	214	3	unfold	unfold	NOUN
bjos-8668749	214	4	easily	easily	ADV
bjos-8668749	214	5	are	be	AUX
bjos-8668749	214	6	those	those	PRON
bjos-8668749	214	7	that	that	PRON
bjos-8668749	214	8	expose	expose	VERB
bjos-8668749	214	9	the	the	DET
bjos-8668749	214	10	greatest	great	ADJ
bjos-8668749	214	11	number	number	NOUN
bjos-8668749	214	12	of	of	ADP
bjos-8668749	214	13	contact	contact	NOUN
bjos-8668749	214	14	sites25	sites25	NOUN
bjos-8668749	214	15	.	.	PUNCT
bjos-8668749	215	1	according	accord	VERB
bjos-8668749	215	2	to	to	ADP
bjos-8668749	215	3	elias	elias	PROPN
bjos-8668749	215	4	et	et	PROPN
bjos-8668749	215	5	al.3	al.3	PROPN
bjos-8668749	215	6	(	(	PUNCT
bjos-8668749	215	7	2011	2011	NUM
bjos-8668749	215	8	)	)	PUNCT
bjos-8668749	215	9	the	the	DET
bjos-8668749	215	10	chemical	chemical	NOUN
bjos-8668749	215	11	composition	composition	NOUN
bjos-8668749	215	12	of	of	ADP
bjos-8668749	215	13	the	the	DET
bjos-8668749	215	14	surface	surface	NOUN
bjos-8668749	215	15	of	of	ADP
bjos-8668749	215	16	titanium	titanium	NOUN
bjos-8668749	215	17	implants	implant	NOUN
bjos-8668749	215	18	practically	practically	ADV
bjos-8668749	215	19	selects	select	VERB
bjos-8668749	215	20	the	the	DET
bjos-8668749	215	21	type	type	NOUN
bjos-8668749	215	22	of	of	ADP
bjos-8668749	215	23	anchoring	anchor	VERB
bjos-8668749	215	24	protein	protein	NOUN
bjos-8668749	215	25	.	.	PUNCT
bjos-8668749	216	1	titanium	titanium	NOUN
bjos-8668749	216	2	oxide	oxide	NOUN
bjos-8668749	216	3	allows	allow	VERB
bjos-8668749	216	4	osteoblasts	osteoblast	NOUN
bjos-8668749	216	5	to	to	PART
bjos-8668749	216	6	adhere	adhere	VERB
bjos-8668749	216	7	via	via	ADP
bjos-8668749	216	8	proteins	protein	NOUN
bjos-8668749	216	9	.	.	PUNCT
bjos-8668749	217	1	adhesion	adhesion	NOUN
bjos-8668749	217	2	of	of	ADP
bjos-8668749	217	3	osteoblasts	osteoblast	NOUN
bjos-8668749	217	4	on	on	ADP
bjos-8668749	217	5	stainless	stainless	ADJ
bjos-8668749	217	6	steel	steel	NOUN
bjos-8668749	217	7	and	and	CCONJ
bjos-8668749	217	8	zirconium	zirconium	NOUN
bjos-8668749	217	9	surface	surface	NOUN
bjos-8668749	217	10	is	be	AUX
bjos-8668749	217	11	negligible	negligible	ADJ
bjos-8668749	217	12	.	.	PUNCT
bjos-8668749	218	1	thus	thus	ADV
bjos-8668749	218	2	,	,	PUNCT
bjos-8668749	218	3	surfaces	surface	NOUN
bjos-8668749	218	4	with	with	ADP
bjos-8668749	218	5	higher	high	ADJ
bjos-8668749	218	6	roughness	roughness	NOUN
bjos-8668749	218	7	have	have	VERB
bjos-8668749	218	8	more	more	ADJ
bjos-8668749	218	9	contact	contact	NOUN
bjos-8668749	218	10	area	area	NOUN
bjos-8668749	218	11	than	than	ADP
bjos-8668749	218	12	the	the	DET
bjos-8668749	218	13	ones	one	NOUN
bjos-8668749	218	14	with	with	ADP
bjos-8668749	218	15	lower	low	ADJ
bjos-8668749	218	16	roughness	roughness	NOUN
bjos-8668749	218	17	,	,	PUNCT
bjos-8668749	218	18	or	or	CCONJ
bjos-8668749	218	19	smooth	smooth	ADJ
bjos-8668749	218	20	surfaces	surface	NOUN
bjos-8668749	218	21	,	,	PUNCT
bjos-8668749	218	22	referring	refer	VERB
bjos-8668749	218	23	to	to	ADP
bjos-8668749	218	24	the	the	DET
bjos-8668749	218	25	machining	machining	NOUN
bjos-8668749	218	26	processes	process	NOUN
bjos-8668749	218	27	.	.	PUNCT
bjos-8668749	219	1	in	in	ADP
bjos-8668749	219	2	this	this	DET
bjos-8668749	219	3	sense	sense	NOUN
bjos-8668749	219	4	,	,	PUNCT
bjos-8668749	219	5	focusing	focus	VERB
bjos-8668749	219	6	on	on	ADP
bjos-8668749	219	7	better	well	ADJ
bjos-8668749	219	8	osseointegration	osseointegration	NOUN
bjos-8668749	219	9	performance	performance	NOUN
bjos-8668749	219	10	,	,	PUNCT
bjos-8668749	219	11	several	several	ADJ
bjos-8668749	219	12	researchers	researcher	NOUN
bjos-8668749	219	13	,	,	PUNCT
bjos-8668749	219	14	in	in	ADP
bjos-8668749	219	15	an	an	DET
bjos-8668749	219	16	attempt	attempt	NOUN
bjos-8668749	219	17	to	to	PART
bjos-8668749	219	18	improve	improve	VERB
bjos-8668749	219	19	the	the	DET
bjos-8668749	219	20	osseointegrable	osseointegrable	ADJ
bjos-8668749	219	21	implants	implant	NOUN
bjos-8668749	219	22	performance	performance	NOUN
bjos-8668749	219	23	,	,	PUNCT
bjos-8668749	219	24	have	have	AUX
bjos-8668749	219	25	made	make	VERB
bjos-8668749	219	26	use	use	NOUN
bjos-8668749	219	27	of	of	ADP
bjos-8668749	219	28	mimicking	mimic	VERB
bjos-8668749	219	29	techniques	technique	NOUN
bjos-8668749	219	30	,	,	PUNCT
bjos-8668749	219	31	coating	coat	VERB
bjos-8668749	219	32	the	the	DET
bjos-8668749	219	33	surface	surface	NOUN
bjos-8668749	219	34	with	with	ADP
bjos-8668749	219	35	rgd41	rgd41	NOUN
bjos-8668749	219	36	.	.	PUNCT
bjos-8668749	220	1	the	the	DET
bjos-8668749	220	2	results	result	NOUN
bjos-8668749	220	3	showed	show	VERB
bjos-8668749	220	4	that	that	SCONJ
bjos-8668749	220	5	recognition	recognition	NOUN
bjos-8668749	220	6	of	of	ADP
bjos-8668749	220	7	the	the	DET
bjos-8668749	220	8	rgd	rgd	PROPN
bjos-8668749	220	9	tripeptide	tripeptide	ADV
bjos-8668749	220	10	alone	alone	ADV
bjos-8668749	220	11	is	be	AUX
bjos-8668749	220	12	not	not	PART
bjos-8668749	220	13	sufficient	sufficient	ADJ
bjos-8668749	220	14	to	to	PART
bjos-8668749	220	15	transmit	transmit	VERB
bjos-8668749	220	16	messages	message	NOUN
bjos-8668749	220	17	for	for	SCONJ
bjos-8668749	220	18	cells	cell	NOUN
bjos-8668749	220	19	to	to	PART
bjos-8668749	220	20	form	form	VERB
bjos-8668749	220	21	tissue	tissue	NOUN
bjos-8668749	220	22	.	.	PUNCT
bjos-8668749	221	1	the	the	DET
bjos-8668749	221	2	cells	cell	NOUN
bjos-8668749	221	3	behavior	behavior	NOUN
bjos-8668749	221	4	depends	depend	VERB
bjos-8668749	221	5	on	on	ADP
bjos-8668749	221	6	the	the	DET
bjos-8668749	221	7	simultaneous	simultaneous	ADJ
bjos-8668749	221	8	association	association	NOUN
bjos-8668749	221	9	of	of	ADP
bjos-8668749	221	10	receptors	receptor	NOUN
bjos-8668749	221	11	,	,	PUNCT
bjos-8668749	221	12	integrins	integrin	NOUN
bjos-8668749	221	13	and	and	CCONJ
bjos-8668749	221	14	co	co	NOUN
bjos-8668749	221	15	-	-	NOUN
bjos-8668749	221	16	receptors	receptor	NOUN
bjos-8668749	221	17	present	present	ADJ
bjos-8668749	221	18	on	on	ADP
bjos-8668749	221	19	the	the	DET
bjos-8668749	221	20	membrane	membrane	NOUN
bjos-8668749	221	21	and	and	CCONJ
bjos-8668749	221	22	in	in	ADP
bjos-8668749	221	23	the	the	DET
bjos-8668749	221	24	cells	cell	NOUN
bjos-8668749	221	25	cytoplasm	cytoplasm	VERB
bjos-8668749	221	26	.	.	PUNCT
bjos-8668749	222	1	for	for	SCONJ
bjos-8668749	222	2	the	the	DET
bjos-8668749	222	3	cell	cell	NOUN
bjos-8668749	222	4	to	to	PART
bjos-8668749	222	5	have	have	VERB
bjos-8668749	222	6	a	a	DET
bjos-8668749	222	7	specific	specific	ADJ
bjos-8668749	222	8	response	response	NOUN
bjos-8668749	222	9	,	,	PUNCT
bjos-8668749	222	10	it	it	PRON
bjos-8668749	222	11	must	must	AUX
bjos-8668749	222	12	decipher	decipher	VERB
bjos-8668749	222	13	the	the	DET
bjos-8668749	222	14	complete	complete	ADJ
bjos-8668749	222	15	message	message	NOUN
bjos-8668749	222	16	,	,	PUNCT
bjos-8668749	222	17	such	such	ADJ
bjos-8668749	222	18	as	as	ADP
bjos-8668749	222	19	fibronectin	fibronectin	NOUN
bjos-8668749	222	20	,	,	PUNCT
bjos-8668749	222	21	and	and	CCONJ
bjos-8668749	222	22	not	not	PART
bjos-8668749	222	23	just	just	ADV
bjos-8668749	222	24	a	a	DET
bjos-8668749	222	25	part	part	NOUN
bjos-8668749	222	26	of	of	ADP
bjos-8668749	222	27	the	the	DET
bjos-8668749	222	28	message	message	NOUN
bjos-8668749	222	29	containing	contain	VERB
bjos-8668749	222	30	one	one	NUM
bjos-8668749	222	31	of	of	ADP
bjos-8668749	222	32	the	the	DET
bjos-8668749	222	33	amino	amino	ADJ
bjos-8668749	222	34	acids	acid	NOUN
bjos-8668749	222	35	of	of	ADP
bjos-8668749	222	36	the	the	DET
bjos-8668749	222	37	rgd	rgd	NOUN
bjos-8668749	222	38	sequence	sequence	NOUN
bjos-8668749	222	39	.	.	PUNCT
bjos-8668749	223	1	based	base	VERB
bjos-8668749	223	2	on	on	ADP
bjos-8668749	223	3	these	these	DET
bjos-8668749	223	4	results	result	NOUN
bjos-8668749	223	5	,	,	PUNCT
bjos-8668749	223	6	implant	implant	ADJ
bjos-8668749	223	7	surface	surface	NOUN
bjos-8668749	223	8	treatments	treatment	NOUN
bjos-8668749	223	9	were	be	AUX
bjos-8668749	223	10	developed	develop	VERB
bjos-8668749	223	11	with	with	ADP
bjos-8668749	223	12	surface	surface	NOUN
bjos-8668749	223	13	properties	property	NOUN
bjos-8668749	223	14	that	that	PRON
bjos-8668749	223	15	favor	favor	VERB
bjos-8668749	223	16	the	the	DET
bjos-8668749	223	17	unfolding	unfolding	NOUN
bjos-8668749	223	18	and	and	CCONJ
bjos-8668749	223	19	elongation	elongation	NOUN
bjos-8668749	223	20	of	of	ADP
bjos-8668749	223	21	fn	fn	NOUN
bjos-8668749	223	22	to	to	PART
bjos-8668749	223	23	increase	increase	VERB
bjos-8668749	223	24	their	their	PRON
bjos-8668749	223	25	binding	binding	ADJ
bjos-8668749	223	26	and	and	CCONJ
bjos-8668749	223	27	attachment	attachment	NOUN
bjos-8668749	223	28	to	to	ADP
bjos-8668749	223	29	the	the	DET
bjos-8668749	223	30	implant	implant	ADJ
bjos-8668749	223	31	surface	surface	NOUN
bjos-8668749	223	32	.	.	PUNCT
bjos-8668749	224	1	it	it	PRON
bjos-8668749	224	2	can	can	AUX
bjos-8668749	224	3	be	be	AUX
bjos-8668749	224	4	observed	observe	VERB
bjos-8668749	224	5	that	that	SCONJ
bjos-8668749	224	6	cell	cell	NOUN
bjos-8668749	224	7	spreading	spread	VERB
bjos-8668749	224	8	and	and	CCONJ
bjos-8668749	224	9	its	its	PRON
bjos-8668749	224	10	incorporation	incorporation	NOUN
bjos-8668749	224	11	into	into	ADP
bjos-8668749	224	12	the	the	DET
bjos-8668749	224	13	surface	surface	NOUN
bjos-8668749	224	14	are	be	AUX
bjos-8668749	224	15	rapid	rapid	ADJ
bjos-8668749	224	16	on	on	ADP
bjos-8668749	224	17	fibronectin	fibronectin	NOUN
bjos-8668749	224	18	-	-	PUNCT
bjos-8668749	224	19	coated	coat	VERB
bjos-8668749	224	20	surfaces	surface	NOUN
bjos-8668749	224	21	at	at	ADP
bjos-8668749	224	22	ph4,5	ph4,5	NOUN
bjos-8668749	224	23	.	.	PUNCT
bjos-8668749	225	1	in	in	ADP
bjos-8668749	225	2	this	this	DET
bjos-8668749	225	3	condition	condition	NOUN
bjos-8668749	225	4	,	,	PUNCT
bjos-8668749	225	5	fibronectin	fibronectin	NOUN
bjos-8668749	225	6	exposes	expose	VERB
bjos-8668749	225	7	all	all	DET
bjos-8668749	225	8	its	its	PRON
bjos-8668749	225	9	parts	part	NOUN
bjos-8668749	225	10	,	,	PUNCT
bjos-8668749	225	11	in	in	ADP
bjos-8668749	225	12	particular	particular	ADJ
bjos-8668749	225	13	the	the	DET
bjos-8668749	225	14	rgd	rgd	PROPN
bjos-8668749	225	15	region	region	NOUN
bjos-8668749	225	16	,	,	PUNCT
bjos-8668749	225	17	which	which	PRON
bjos-8668749	225	18	is	be	AUX
bjos-8668749	225	19	recognized	recognize	VERB
bjos-8668749	225	20	by	by	ADP
bjos-8668749	225	21	intracellular	intracellular	ADJ
bjos-8668749	225	22	receptors	receptor	NOUN
bjos-8668749	225	23	.	.	PUNCT
bjos-8668749	226	1	the	the	DET
bjos-8668749	226	2	result	result	NOUN
bjos-8668749	226	3	is	be	AUX
bjos-8668749	226	4	spreading	spread	VERB
bjos-8668749	226	5	or	or	CCONJ
bjos-8668749	226	6	adhesion	adhesion	NOUN
bjos-8668749	226	7	of	of	ADP
bjos-8668749	226	8	cells	cell	NOUN
bjos-8668749	226	9	on	on	ADP
bjos-8668749	226	10	the	the	DET
bjos-8668749	226	11	surface3	surface3	NOUN
bjos-8668749	226	12	.	.	PUNCT
bjos-8668749	227	1	schierano	schierano	NOUN
bjos-8668749	227	2	et	et	NOUN
bjos-8668749	227	3	al.42	al.42	NOUN
bjos-8668749	227	4	(	(	PUNCT
bjos-8668749	227	5	2021	2021	NUM
bjos-8668749	227	6	)	)	PUNCT
bjos-8668749	227	7	point	point	VERB
bjos-8668749	227	8	out	out	ADP
bjos-8668749	227	9	that	that	SCONJ
bjos-8668749	227	10	cell	cell	NOUN
bjos-8668749	227	11	attachment	attachment	NOUN
bjos-8668749	227	12	is	be	AUX
bjos-8668749	227	13	enhanced	enhance	VERB
bjos-8668749	227	14	by	by	ADP
bjos-8668749	227	15	additional	additional	ADJ
bjos-8668749	227	16	synthesis	synthesis	NOUN
bjos-8668749	227	17	and	and	CCONJ
bjos-8668749	227	18	deposition	deposition	NOUN
bjos-8668749	227	19	of	of	ADP
bjos-8668749	227	20	proteins	protein	NOUN
bjos-8668749	227	21	that	that	PRON
bjos-8668749	227	22	promote	promote	VERB
bjos-8668749	227	23	stronger	strong	ADJ
bjos-8668749	227	24	binding	bind	VERB
bjos-8668749	227	25	.	.	PUNCT
bjos-8668749	228	1	the	the	DET
bjos-8668749	228	2	adsorbed	adsorb	VERB
bjos-8668749	228	3	protein	protein	NOUN
bjos-8668749	228	4	layer	layer	NOUN
bjos-8668749	228	5	mediates	mediate	VERB
bjos-8668749	228	6	subsequent	subsequent	ADJ
bjos-8668749	228	7	interactions	interaction	NOUN
bjos-8668749	228	8	with	with	ADP
bjos-8668749	228	9	cells	cell	NOUN
bjos-8668749	228	10	in	in	ADP
bjos-8668749	228	11	neighboring	neighboring	NOUN
bjos-8668749	228	12	tissues	tissue	NOUN
bjos-8668749	228	13	,	,	PUNCT
bjos-8668749	228	14	promoting	promote	VERB
bjos-8668749	228	15	cellular	cellular	ADJ
bjos-8668749	228	16	functions	function	NOUN
bjos-8668749	228	17	pertinent	pertinent	ADJ
bjos-8668749	228	18	to	to	ADP
bjos-8668749	228	19	new	new	ADJ
bjos-8668749	228	20	tissue	tissue	NOUN
bjos-8668749	228	21	formation	formation	NOUN
bjos-8668749	228	22	,	,	PUNCT
bjos-8668749	228	23	leading	lead	VERB
bjos-8668749	228	24	to	to	ADP
bjos-8668749	228	25	implant	implant	ADJ
bjos-8668749	228	26	integration	integration	NOUN
bjos-8668749	228	27	and	and	CCONJ
bjos-8668749	228	28	stabilization	stabilization	NOUN
bjos-8668749	228	29	.	.	PUNCT
bjos-8668749	229	1	the	the	DET
bjos-8668749	229	2	chemical	chemical	ADJ
bjos-8668749	229	3	and	and	CCONJ
bjos-8668749	229	4	physical	physical	ADJ
bjos-8668749	229	5	characteristics	characteristic	NOUN
bjos-8668749	229	6	of	of	ADP
bjos-8668749	229	7	the	the	DET
bjos-8668749	229	8	material	material	NOUN
bjos-8668749	229	9	surface	surface	NOUN
bjos-8668749	229	10	influence	influence	NOUN
bjos-8668749	229	11	the	the	DET
bjos-8668749	229	12	amount	amount	NOUN
bjos-8668749	229	13	,	,	PUNCT
bjos-8668749	229	14	distribution	distribution	NOUN
bjos-8668749	229	15	,	,	PUNCT
bjos-8668749	229	16	density	density	NOUN
bjos-8668749	229	17	,	,	PUNCT
bjos-8668749	229	18	conformation	conformation	NOUN
bjos-8668749	229	19	,	,	PUNCT
bjos-8668749	229	20	and	and	CCONJ
bjos-8668749	229	21	orientation	orientation	NOUN
bjos-8668749	229	22	of	of	ADP
bjos-8668749	229	23	the	the	DET
bjos-8668749	229	24	adsorbed	adsorb	VERB
bjos-8668749	229	25	proteins	protein	NOUN
bjos-8668749	229	26	.	.	PUNCT
bjos-8668749	230	1	although	although	SCONJ
bjos-8668749	230	2	all	all	DET
bjos-8668749	230	3	the	the	DET
bjos-8668749	230	4	underlying	underlie	VERB
bjos-8668749	230	5	aspects	aspect	NOUN
bjos-8668749	230	6	and	and	CCONJ
bjos-8668749	230	7	mechanisms	mechanism	NOUN
bjos-8668749	230	8	of	of	ADP
bjos-8668749	230	9	protein	protein	NOUN
bjos-8668749	230	10	interactions	interaction	NOUN
bjos-8668749	230	11	with	with	ADP
bjos-8668749	230	12	the	the	DET
bjos-8668749	230	13	surface	surface	NOUN
bjos-8668749	230	14	are	be	AUX
bjos-8668749	230	15	not	not	PART
bjos-8668749	230	16	well	well	ADV
bjos-8668749	230	17	understood	understand	VERB
bjos-8668749	230	18	,	,	PUNCT
bjos-8668749	230	19	it	it	PRON
bjos-8668749	230	20	is	be	AUX
bjos-8668749	230	21	known	know	VERB
bjos-8668749	230	22	that	that	SCONJ
bjos-8668749	230	23	the	the	DET
bjos-8668749	230	24	chemical	chemical	NOUN
bjos-8668749	230	25	composition	composition	NOUN
bjos-8668749	230	26	of	of	ADP
bjos-8668749	230	27	the	the	DET
bjos-8668749	230	28	biomaterial	biomaterial	ADJ
bjos-8668749	230	29	surface	surface	NOUN
bjos-8668749	230	30	is	be	AUX
bjos-8668749	230	31	a	a	DET
bjos-8668749	230	32	determining	determine	VERB
bjos-8668749	230	33	factor	factor	NOUN
bjos-8668749	230	34	.	.	PUNCT
bjos-8668749	231	1	in	in	ADP
bjos-8668749	231	2	addition	addition	NOUN
bjos-8668749	231	3	to	to	ADP
bjos-8668749	231	4	composition	composition	NOUN
bjos-8668749	231	5	,	,	PUNCT
bjos-8668749	231	6	surface	surface	NOUN
bjos-8668749	231	7	topography	topography	NOUN
bjos-8668749	231	8	also	also	ADV
bjos-8668749	231	9	plays	play	VERB
bjos-8668749	231	10	an	an	DET
bjos-8668749	231	11	important	important	ADJ
bjos-8668749	231	12	role	role	NOUN
bjos-8668749	231	13	in	in	ADP
bjos-8668749	231	14	osseointegration	osseointegration	NOUN
bjos-8668749	231	15	.	.	PUNCT
bjos-8668749	232	1	for	for	ADP
bjos-8668749	232	2	example	example	NOUN
bjos-8668749	232	3	,	,	PUNCT
bjos-8668749	232	4	morphologies	morphology	NOUN
bjos-8668749	232	5	with	with	ADP
bjos-8668749	232	6	nanometric	nanometric	NOUN
bjos-8668749	232	7	features	feature	NOUN
bjos-8668749	232	8	enhance	enhance	VERB
bjos-8668749	232	9	cellular	cellular	ADJ
bjos-8668749	232	10	functions	function	NOUN
bjos-8668749	232	11	compared	compare	VERB
bjos-8668749	232	12	to	to	ADP
bjos-8668749	232	13	microstructured	microstructured	ADJ
bjos-8668749	232	14	surfaces	surface	NOUN
bjos-8668749	232	15	.	.	PUNCT
bjos-8668749	233	1	although	although	SCONJ
bjos-8668749	233	2	there	there	PRON
bjos-8668749	233	3	are	be	VERB
bjos-8668749	233	4	several	several	ADJ
bjos-8668749	233	5	papers	paper	NOUN
bjos-8668749	233	6	that	that	PRON
bjos-8668749	233	7	have	have	AUX
bjos-8668749	233	8	analyzed	analyze	VERB
bjos-8668749	233	9	the	the	DET
bjos-8668749	233	10	biomaterial	biomaterial	ADJ
bjos-8668749	233	11	-	-	PUNCT
bjos-8668749	233	12	tissue	tissue	NOUN
bjos-8668749	233	13	interface	interface	NOUN
bjos-8668749	233	14	,	,	PUNCT
bjos-8668749	233	15	knowledge	knowledge	NOUN
bjos-8668749	233	16	gaps	gap	NOUN
bjos-8668749	233	17	still	still	ADV
bjos-8668749	233	18	exist	exist	VERB
bjos-8668749	233	19	to	to	PART
bjos-8668749	233	20	explain	explain	VERB
bjos-8668749	233	21	how	how	SCONJ
bjos-8668749	233	22	the	the	DET
bjos-8668749	233	23	biomaterial	biomaterial	ADJ
bjos-8668749	233	24	surface	surface	NOUN
bjos-8668749	233	25	properties	property	NOUN
bjos-8668749	233	26	and	and	CCONJ
bjos-8668749	233	27	the	the	DET
bjos-8668749	233	28	adsorbed	adsorb	VERB
bjos-8668749	233	29	protein	protein	NOUN
bjos-8668749	233	30	layer	layer	NOUN
bjos-8668749	233	31	affect	affect	VERB
bjos-8668749	233	32	cell	cell	NOUN
bjos-8668749	233	33	behavior42	behavior42	NOUN
bjos-8668749	233	34	.	.	PUNCT
bjos-8668749	234	1	12	12	NUM
bjos-8668749	234	2	nascimento	nascimento	PROPN
bjos-8668749	234	3	et	et	PROPN
bjos-8668749	234	4	al	al	PROPN
bjos-8668749	234	5	.	.	PROPN
bjos-8668749	235	1	braz	braz	PROPN
bjos-8668749	235	2	j	j	PROPN
bjos-8668749	235	3	oral	oral	PROPN
bjos-8668749	235	4	sci	sci	PROPN
bjos-8668749	235	5	.	.	PUNCT
bjos-8668749	236	1	2023;22	2023;22	NUM
bjos-8668749	236	2	:	:	PUNCT
bjos-8668749	236	3	e238749	e238749	VERB
bjos-8668749	236	4	the	the	DET
bjos-8668749	236	5	unfolded	unfolded	ADJ
bjos-8668749	236	6	fn	fn	NOUN
bjos-8668749	236	7	acts	act	NOUN
bjos-8668749	236	8	as	as	ADP
bjos-8668749	236	9	a	a	DET
bjos-8668749	236	10	binding	bind	VERB
bjos-8668749	236	11	site	site	NOUN
bjos-8668749	236	12	for	for	ADP
bjos-8668749	236	13	many	many	ADJ
bjos-8668749	236	14	proteins	protein	NOUN
bjos-8668749	236	15	and	and	CCONJ
bjos-8668749	236	16	growth	growth	NOUN
bjos-8668749	236	17	factors	factor	NOUN
bjos-8668749	236	18	,	,	PUNCT
bjos-8668749	236	19	including	include	VERB
bjos-8668749	236	20	bmp-2	bmp-2	NUM
bjos-8668749	236	21	and	and	CCONJ
bjos-8668749	236	22	,	,	PUNCT
bjos-8668749	236	23	favors	favor	VERB
bjos-8668749	236	24	the	the	DET
bjos-8668749	236	25	differentiation	differentiation	NOUN
bjos-8668749	236	26	of	of	ADP
bjos-8668749	236	27	mesenchymal	mesenchymal	ADJ
bjos-8668749	236	28	stem	stem	NOUN
bjos-8668749	236	29	cells	cell	NOUN
bjos-8668749	236	30	.	.	PUNCT
bjos-8668749	237	1	work	work	NOUN
bjos-8668749	237	2	has	have	AUX
bjos-8668749	237	3	shown	show	VERB
bjos-8668749	237	4	that	that	SCONJ
bjos-8668749	237	5	the	the	DET
bjos-8668749	237	6	number	number	NOUN
bjos-8668749	237	7	of	of	ADP
bjos-8668749	237	8	osteoblasts	osteoblast	NOUN
bjos-8668749	237	9	in	in	ADP
bjos-8668749	237	10	the	the	DET
bjos-8668749	237	11	bone	bone	NOUN
bjos-8668749	237	12	surrounding	surround	VERB
bjos-8668749	237	13	implants	implant	NOUN
bjos-8668749	237	14	with	with	ADP
bjos-8668749	237	15	a	a	DET
bjos-8668749	237	16	surface	surface	NOUN
bjos-8668749	237	17	containing	contain	VERB
bjos-8668749	237	18	fn	fn	NOUN
bjos-8668749	237	19	is	be	AUX
bjos-8668749	237	20	higher	high	ADJ
bjos-8668749	237	21	than	than	ADP
bjos-8668749	237	22	that	that	PRON
bjos-8668749	237	23	observed	observe	VERB
bjos-8668749	237	24	in	in	ADP
bjos-8668749	237	25	implants	implant	NOUN
bjos-8668749	237	26	without	without	ADP
bjos-8668749	237	27	fn	fn	PROPN
bjos-8668749	237	28	.	.	PUNCT
bjos-8668749	238	1	the	the	DET
bjos-8668749	238	2	number	number	NOUN
bjos-8668749	238	3	of	of	ADP
bjos-8668749	238	4	osteoblasts	osteoblast	NOUN
bjos-8668749	238	5	is	be	AUX
bjos-8668749	238	6	higher	high	ADJ
bjos-8668749	238	7	7	7	NUM
bjos-8668749	238	8	days	day	NOUN
bjos-8668749	238	9	after	after	ADP
bjos-8668749	238	10	surgery	surgery	NOUN
bjos-8668749	238	11	.	.	PUNCT
bjos-8668749	239	1	this	this	DET
bjos-8668749	239	2	result	result	NOUN
bjos-8668749	239	3	confirms	confirm	VERB
bjos-8668749	239	4	the	the	DET
bjos-8668749	239	5	ability	ability	NOUN
bjos-8668749	239	6	of	of	ADP
bjos-8668749	239	7	fn	fn	NOUN
bjos-8668749	239	8	to	to	PART
bjos-8668749	239	9	facilitate	facilitate	VERB
bjos-8668749	239	10	early	early	ADJ
bjos-8668749	239	11	adhesion	adhesion	NOUN
bjos-8668749	239	12	and	and	CCONJ
bjos-8668749	239	13	differentiation	differentiation	NOUN
bjos-8668749	239	14	of	of	ADP
bjos-8668749	239	15	osteoblasts	osteoblast	NOUN
bjos-8668749	239	16	.	.	PUNCT
bjos-8668749	240	1	in	in	ADP
bjos-8668749	240	2	fn	fn	ADV
bjos-8668749	240	3	-	-	PUNCT
bjos-8668749	240	4	treated	treat	VERB
bjos-8668749	240	5	implants	implant	NOUN
bjos-8668749	240	6	,	,	PUNCT
bjos-8668749	240	7	the	the	DET
bjos-8668749	240	8	number	number	NOUN
bjos-8668749	240	9	of	of	ADP
bjos-8668749	240	10	inflammatory	inflammatory	ADJ
bjos-8668749	240	11	cells	cell	NOUN
bjos-8668749	240	12	was	be	AUX
bjos-8668749	240	13	similar	similar	ADJ
bjos-8668749	240	14	to	to	ADP
bjos-8668749	240	15	that	that	PRON
bjos-8668749	240	16	observed	observe	VERB
bjos-8668749	240	17	in	in	ADP
bjos-8668749	240	18	control	control	NOUN
bjos-8668749	240	19	sites	site	NOUN
bjos-8668749	240	20	at	at	ADP
bjos-8668749	240	21	7	7	NUM
bjos-8668749	240	22	days	day	NOUN
bjos-8668749	240	23	and	and	CCONJ
bjos-8668749	240	24	decreased	decrease	VERB
bjos-8668749	240	25	over	over	ADP
bjos-8668749	240	26	time	time	NOUN
bjos-8668749	240	27	.	.	PUNCT
bjos-8668749	241	1	in	in	ADP
bjos-8668749	241	2	addition	addition	NOUN
bjos-8668749	241	3	,	,	PUNCT
bjos-8668749	241	4	fn	fn	NOUN
bjos-8668749	241	5	reduces	reduce	VERB
bjos-8668749	241	6	inflammation	inflammation	NOUN
bjos-8668749	241	7	,	,	PUNCT
bjos-8668749	241	8	with	with	SCONJ
bjos-8668749	241	9	a	a	DET
bjos-8668749	241	10	decrease	decrease	NOUN
bjos-8668749	241	11	in	in	ADP
bjos-8668749	241	12	il-1β	il-1β	PROPN
bjos-8668749	241	13	expression	expression	NOUN
bjos-8668749	241	14	observed	observe	VERB
bjos-8668749	241	15	.	.	PUNCT
bjos-8668749	242	1	few	few	ADJ
bjos-8668749	242	2	research	research	NOUN
bjos-8668749	242	3	papers	paper	NOUN
bjos-8668749	242	4	have	have	AUX
bjos-8668749	242	5	analyzed	analyze	VERB
bjos-8668749	242	6	the	the	DET
bjos-8668749	242	7	pro	pro	ADJ
bjos-8668749	242	8	-	-	ADJ
bjos-8668749	242	9	inflammatory	inflammatory	ADJ
bjos-8668749	242	10	or	or	CCONJ
bjos-8668749	242	11	anti	anti	ADJ
bjos-8668749	242	12	-	-	ADJ
bjos-8668749	242	13	inflammatory	inflammatory	ADJ
bjos-8668749	242	14	properties	property	NOUN
bjos-8668749	242	15	of	of	ADP
bjos-8668749	242	16	fn	fn	NOUN
bjos-8668749	242	17	.	.	PUNCT
bjos-8668749	243	1	the	the	DET
bjos-8668749	243	2	reported	report	VERB
bjos-8668749	243	3	results	result	NOUN
bjos-8668749	243	4	are	be	AUX
bjos-8668749	243	5	contradictory	contradictory	ADJ
bjos-8668749	243	6	,	,	PUNCT
bjos-8668749	243	7	mainly	mainly	ADV
bjos-8668749	243	8	regarding	regard	VERB
bjos-8668749	243	9	the	the	DET
bjos-8668749	243	10	experimental	experimental	ADJ
bjos-8668749	243	11	protocol	protocol	NOUN
bjos-8668749	243	12	used	use	VERB
bjos-8668749	243	13	.	.	PUNCT
bjos-8668749	244	1	the	the	DET
bjos-8668749	244	2	heparin	heparin	NOUN
bjos-8668749	244	3	/	/	SYM
bjos-8668749	244	4	fibronectin	fibronectin	NOUN
bjos-8668749	244	5	complex	complex	NOUN
bjos-8668749	244	6	immobilized	immobilize	VERB
bjos-8668749	244	7	early	early	ADV
bjos-8668749	244	8	on	on	ADP
bjos-8668749	244	9	the	the	DET
bjos-8668749	244	10	titanium	titanium	NOUN
bjos-8668749	244	11	surface	surface	NOUN
bjos-8668749	244	12	decreases	decrease	VERB
bjos-8668749	244	13	the	the	DET
bjos-8668749	244	14	number	number	NOUN
bjos-8668749	244	15	of	of	ADP
bjos-8668749	244	16	macrophages	macrophage	NOUN
bjos-8668749	244	17	and	and	CCONJ
bjos-8668749	244	18	their	their	PRON
bjos-8668749	244	19	response	response	NOUN
bjos-8668749	244	20	to	to	ADP
bjos-8668749	244	21	tnfα	tnfα	NOUN
bjos-8668749	244	22	,	,	PUNCT
bjos-8668749	244	23	a	a	DET
bjos-8668749	244	24	known	know	VERB
bjos-8668749	244	25	pro	pro	ADJ
bjos-8668749	244	26	-	-	ADJ
bjos-8668749	244	27	inflammatory	inflammatory	ADJ
bjos-8668749	244	28	molecule	molecule	NOUN
bjos-8668749	244	29	.	.	PUNCT
bjos-8668749	245	1	furthermore	furthermore	ADV
bjos-8668749	245	2	,	,	PUNCT
bjos-8668749	245	3	a	a	DET
bjos-8668749	245	4	decrease	decrease	NOUN
bjos-8668749	245	5	in	in	ADP
bjos-8668749	245	6	il-1β	il-1β	PROPN
bjos-8668749	245	7	release	release	NOUN
bjos-8668749	245	8	was	be	AUX
bjos-8668749	245	9	also	also	ADV
bjos-8668749	245	10	observed	observe	VERB
bjos-8668749	245	11	in	in	ADP
bjos-8668749	245	12	the	the	DET
bjos-8668749	245	13	heparin	heparin	NOUN
bjos-8668749	245	14	/	/	SYM
bjos-8668749	245	15	fibronectin	fibronectin	NOUN
bjos-8668749	245	16	treated	treat	VERB
bjos-8668749	245	17	implants	implant	NOUN
bjos-8668749	245	18	.	.	PUNCT
bjos-8668749	246	1	a	a	DET
bjos-8668749	246	2	similar	similar	ADJ
bjos-8668749	246	3	anti	anti	ADJ
bjos-8668749	246	4	-	-	ADJ
bjos-8668749	246	5	inflammatory	inflammatory	ADJ
bjos-8668749	246	6	effect	effect	NOUN
bjos-8668749	246	7	was	be	AUX
bjos-8668749	246	8	reported	report	VERB
bjos-8668749	246	9	in	in	ADP
bjos-8668749	246	10	the	the	DET
bjos-8668749	246	11	case	case	NOUN
bjos-8668749	246	12	of	of	ADP
bjos-8668749	246	13	monocyte	monocyte	NOUN
bjos-8668749	246	14	-	-	PUNCT
bjos-8668749	246	15	derived	derive	VERB
bjos-8668749	246	16	macrophages	macrophage	NOUN
bjos-8668749	246	17	seeded	seed	VERB
bjos-8668749	246	18	on	on	ADP
bjos-8668749	246	19	fn	fn	ADV
bjos-8668749	246	20	-	-	PUNCT
bjos-8668749	246	21	coated	coated	ADJ
bjos-8668749	246	22	poly	poly	ADJ
bjos-8668749	246	23	(	(	PUNCT
bjos-8668749	246	24	l	l	ADJ
bjos-8668749	246	25	-	-	ADJ
bjos-8668749	246	26	lactic	lactic	ADJ
bjos-8668749	246	27	acid	acid	NOUN
bjos-8668749	246	28	)	)	PUNCT
bjos-8668749	246	29	films	film	NOUN
bjos-8668749	246	30	,	,	PUNCT
bjos-8668749	246	31	where	where	SCONJ
bjos-8668749	246	32	a	a	DET
bjos-8668749	246	33	significant	significant	ADJ
bjos-8668749	246	34	decrease	decrease	NOUN
bjos-8668749	246	35	in	in	ADP
bjos-8668749	246	36	the	the	DET
bjos-8668749	246	37	release	release	NOUN
bjos-8668749	246	38	of	of	ADP
bjos-8668749	246	39	il-6	il-6	NOUN
bjos-8668749	246	40	(	(	PUNCT
bjos-8668749	246	41	inflammatory	inflammatory	ADJ
bjos-8668749	246	42	cytokines	cytokine	NOUN
bjos-8668749	246	43	)	)	PUNCT
bjos-8668749	246	44	and	and	CCONJ
bjos-8668749	246	45	an	an	DET
bjos-8668749	246	46	increase	increase	NOUN
bjos-8668749	246	47	in	in	ADP
bjos-8668749	246	48	il-10	il-10	PRON
bjos-8668749	246	49	(	(	PUNCT
bjos-8668749	246	50	anti	anti	ADJ
bjos-8668749	246	51	-	-	ADJ
bjos-8668749	246	52	inflammatory	inflammatory	ADJ
bjos-8668749	246	53	protein	protein	NOUN
bjos-8668749	246	54	)	)	PUNCT
bjos-8668749	246	55	were	be	AUX
bjos-8668749	246	56	observed	observe	VERB
bjos-8668749	246	57	.	.	PUNCT
bjos-8668749	247	1	differently	differently	ADV
bjos-8668749	247	2	,	,	PUNCT
bjos-8668749	247	3	fn	fn	ADV
bjos-8668749	247	4	-	-	PUNCT
bjos-8668749	247	5	treated	treat	VERB
bjos-8668749	247	6	expanded	expand	VERB
bjos-8668749	247	7	polytetrafluoroethylene	polytetrafluoroethylene	NOUN
bjos-8668749	247	8	induced	induce	VERB
bjos-8668749	247	9	an	an	DET
bjos-8668749	247	10	extensive	extensive	ADJ
bjos-8668749	247	11	inflammatory	inflammatory	ADJ
bjos-8668749	247	12	process	process	NOUN
bjos-8668749	247	13	when	when	SCONJ
bjos-8668749	247	14	inserted	insert	VERB
bjos-8668749	247	15	into	into	ADP
bjos-8668749	247	16	rat	rat	NOUN
bjos-8668749	247	17	adipose	adipose	ADJ
bjos-8668749	247	18	tissue	tissue	NOUN
bjos-8668749	247	19	.	.	PUNCT
bjos-8668749	248	1	in	in	ADP
bjos-8668749	248	2	this	this	DET
bjos-8668749	248	3	case	case	NOUN
bjos-8668749	248	4	,	,	PUNCT
bjos-8668749	248	5	foreign	foreign	ADJ
bjos-8668749	248	6	body	body	NOUN
bjos-8668749	248	7	giant	giant	ADJ
bjos-8668749	248	8	cells	cell	NOUN
bjos-8668749	248	9	typical	typical	ADJ
bjos-8668749	248	10	of	of	ADP
bjos-8668749	248	11	chronic	chronic	ADJ
bjos-8668749	248	12	inflammation	inflammation	NOUN
bjos-8668749	248	13	were	be	AUX
bjos-8668749	248	14	also	also	ADV
bjos-8668749	248	15	observed	observe	VERB
bjos-8668749	248	16	.	.	PUNCT
bjos-8668749	249	1	following	follow	VERB
bjos-8668749	249	2	this	this	DET
bjos-8668749	249	3	line	line	NOUN
bjos-8668749	249	4	,	,	PUNCT
bjos-8668749	249	5	a	a	DET
bjos-8668749	249	6	main	main	ADJ
bjos-8668749	249	7	limitation	limitation	NOUN
bjos-8668749	249	8	of	of	ADP
bjos-8668749	249	9	this	this	DET
bjos-8668749	249	10	results	result	NOUN
bjos-8668749	249	11	was	be	AUX
bjos-8668749	249	12	the	the	DET
bjos-8668749	249	13	absence	absence	NOUN
bjos-8668749	249	14	of	of	ADP
bjos-8668749	249	15	articles	article	NOUN
bjos-8668749	249	16	that	that	PRON
bjos-8668749	249	17	evaluate	evaluate	VERB
bjos-8668749	249	18	the	the	DET
bjos-8668749	249	19	biochemical	biochemical	ADJ
bjos-8668749	249	20	mechanisms	mechanism	NOUN
bjos-8668749	249	21	of	of	ADP
bjos-8668749	249	22	integrin	integrin	NOUN
bjos-8668749	249	23	-	-	PUNCT
bjos-8668749	249	24	fibronectin	fibronectin	NOUN
bjos-8668749	249	25	-	-	PUNCT
bjos-8668749	249	26	implant	implant	ADJ
bjos-8668749	249	27	interactions	interaction	NOUN
bjos-8668749	249	28	.	.	PUNCT
bjos-8668749	250	1	another	another	DET
bjos-8668749	250	2	factor	factor	NOUN
bjos-8668749	250	3	is	be	AUX
bjos-8668749	250	4	that	that	SCONJ
bjos-8668749	250	5	most	most	ADJ
bjos-8668749	250	6	articles	article	NOUN
bjos-8668749	250	7	do	do	AUX
bjos-8668749	250	8	not	not	PART
bjos-8668749	250	9	explicitly	explicitly	ADV
bjos-8668749	250	10	suggest	suggest	VERB
bjos-8668749	250	11	the	the	DET
bjos-8668749	250	12	participation	participation	NOUN
bjos-8668749	250	13	of	of	ADP
bjos-8668749	250	14	other	other	ADJ
bjos-8668749	250	15	proteins	protein	NOUN
bjos-8668749	250	16	in	in	ADP
bjos-8668749	250	17	this	this	DET
bjos-8668749	250	18	process	process	NOUN
bjos-8668749	250	19	,	,	PUNCT
bjos-8668749	250	20	and	and	CCONJ
bjos-8668749	250	21	when	when	SCONJ
bjos-8668749	250	22	they	they	PRON
bjos-8668749	250	23	do	do	VERB
bjos-8668749	250	24	,	,	PUNCT
bjos-8668749	250	25	the	the	DET
bjos-8668749	250	26	mechanisms	mechanism	NOUN
bjos-8668749	250	27	are	be	AUX
bjos-8668749	250	28	not	not	PART
bjos-8668749	250	29	clear	clear	ADJ
bjos-8668749	250	30	and/or	and/or	CCONJ
bjos-8668749	250	31	explained	explain	VERB
bjos-8668749	250	32	.	.	PUNCT
bjos-8668749	251	1	another	another	DET
bjos-8668749	251	2	variance	variance	NOUN
bjos-8668749	251	3	is	be	AUX
bjos-8668749	251	4	the	the	DET
bjos-8668749	251	5	type	type	NOUN
bjos-8668749	251	6	of	of	ADP
bjos-8668749	251	7	biomaterial	biomaterial	NOUN
bjos-8668749	251	8	;	;	PUNCT
bjos-8668749	251	9	in	in	ADP
bjos-8668749	251	10	most	most	ADJ
bjos-8668749	251	11	of	of	ADP
bjos-8668749	251	12	the	the	DET
bjos-8668749	251	13	results	result	NOUN
bjos-8668749	251	14	it	it	PRON
bjos-8668749	251	15	is	be	AUX
bjos-8668749	251	16	not	not	PART
bjos-8668749	251	17	identified	identify	VERB
bjos-8668749	251	18	if	if	SCONJ
bjos-8668749	251	19	it	it	PRON
bjos-8668749	251	20	is	be	AUX
bjos-8668749	251	21	commercially	commercially	ADV
bjos-8668749	251	22	pure	pure	ADJ
bjos-8668749	251	23	titanium	titanium	NOUN
bjos-8668749	251	24	(	(	PUNCT
bjos-8668749	251	25	and	and	CCONJ
bjos-8668749	251	26	its	its	PRON
bjos-8668749	251	27	grade	grade	NOUN
bjos-8668749	251	28	)	)	PUNCT
bjos-8668749	251	29	or	or	CCONJ
bjos-8668749	251	30	if	if	SCONJ
bjos-8668749	251	31	it	it	PRON
bjos-8668749	251	32	is	be	AUX
bjos-8668749	251	33	a	a	DET
bjos-8668749	251	34	titanium	titanium	NOUN
bjos-8668749	251	35	alloy	alloy	NOUN
bjos-8668749	251	36	.	.	PUNCT
bjos-8668749	252	1	thus	thus	ADV
bjos-8668749	252	2	,	,	PUNCT
bjos-8668749	252	3	it	it	PRON
bjos-8668749	252	4	is	be	AUX
bjos-8668749	252	5	difficult	difficult	ADJ
bjos-8668749	252	6	to	to	PART
bjos-8668749	252	7	determine	determine	VERB
bjos-8668749	252	8	which	which	DET
bjos-8668749	252	9	factors	factor	NOUN
bjos-8668749	252	10	are	be	AUX
bjos-8668749	252	11	more	more	ADV
bjos-8668749	252	12	significant	significant	ADJ
bjos-8668749	252	13	in	in	ADP
bjos-8668749	252	14	the	the	DET
bjos-8668749	252	15	protein	protein	NOUN
bjos-8668749	252	16	-	-	PUNCT
bjos-8668749	252	17	implant	implant	ADJ
bjos-8668749	252	18	interaction	interaction	NOUN
bjos-8668749	252	19	or	or	CCONJ
bjos-8668749	252	20	even	even	ADV
bjos-8668749	252	21	how	how	SCONJ
bjos-8668749	252	22	or	or	CCONJ
bjos-8668749	252	23	what	what	PRON
bjos-8668749	252	24	explains	explain	VERB
bjos-8668749	252	25	this	this	DET
bjos-8668749	252	26	interface	interface	NOUN
bjos-8668749	252	27	in	in	ADP
bjos-8668749	252	28	the	the	DET
bjos-8668749	252	29	osteoconduction	osteoconduction	NOUN
bjos-8668749	252	30	space	space	NOUN
bjos-8668749	252	31	.	.	PUNCT
bjos-8668749	253	1	conclusion	conclusion	NOUN
bjos-8668749	253	2	in	in	ADP
bjos-8668749	253	3	the	the	DET
bjos-8668749	253	4	present	present	ADJ
bjos-8668749	253	5	work	work	NOUN
bjos-8668749	253	6	the	the	DET
bjos-8668749	253	7	concepts	concept	NOUN
bjos-8668749	253	8	and	and	CCONJ
bjos-8668749	253	9	processes	process	NOUN
bjos-8668749	253	10	involved	involve	VERB
bjos-8668749	253	11	in	in	ADP
bjos-8668749	253	12	osseointegration	osseointegration	NOUN
bjos-8668749	253	13	of	of	ADP
bjos-8668749	253	14	titanium	titanium	NOUN
bjos-8668749	253	15	implants	implant	NOUN
bjos-8668749	253	16	were	be	AUX
bjos-8668749	253	17	presented	present	VERB
bjos-8668749	253	18	.	.	PUNCT
bjos-8668749	254	1	these	these	DET
bjos-8668749	254	2	concepts	concept	NOUN
bjos-8668749	254	3	are	be	AUX
bjos-8668749	254	4	essential	essential	ADJ
bjos-8668749	254	5	to	to	PART
bjos-8668749	254	6	understand	understand	VERB
bjos-8668749	254	7	the	the	DET
bjos-8668749	254	8	influence	influence	NOUN
bjos-8668749	254	9	of	of	ADP
bjos-8668749	254	10	the	the	DET
bjos-8668749	254	11	titanium	titanium	NOUN
bjos-8668749	254	12	implants	implant	NOUN
bjos-8668749	254	13	surface	surface	NOUN
bjos-8668749	254	14	properties	property	NOUN
bjos-8668749	254	15	and	and	CCONJ
bjos-8668749	254	16	to	to	PART
bjos-8668749	254	17	analyze	analyze	VERB
bjos-8668749	254	18	the	the	DET
bjos-8668749	254	19	biological	biological	ADJ
bjos-8668749	254	20	mechanisms	mechanism	NOUN
bjos-8668749	254	21	response	response	NOUN
bjos-8668749	254	22	between	between	ADP
bjos-8668749	254	23	proteins	protein	NOUN
bjos-8668749	254	24	of	of	ADP
bjos-8668749	254	25	the	the	DET
bjos-8668749	254	26	bone	bone	NOUN
bjos-8668749	254	27	tissue	tissue	NOUN
bjos-8668749	254	28	extracellular	extracellular	ADJ
bjos-8668749	254	29	matrix	matrix	NOUN
bjos-8668749	254	30	and	and	CCONJ
bjos-8668749	254	31	biomaterials	biomaterial	NOUN
bjos-8668749	254	32	.	.	PUNCT
bjos-8668749	255	1	in	in	ADP
bjos-8668749	255	2	the	the	DET
bjos-8668749	255	3	osseointegration	osseointegration	NOUN
bjos-8668749	255	4	process	process	NOUN
bjos-8668749	255	5	,	,	PUNCT
bjos-8668749	255	6	fibronectin	fibronectin	NOUN
bjos-8668749	255	7	and	and	CCONJ
bjos-8668749	255	8	integrin	integrin	NOUN
bjos-8668749	255	9	are	be	AUX
bjos-8668749	255	10	one	one	NUM
bjos-8668749	255	11	of	of	ADP
bjos-8668749	255	12	the	the	DET
bjos-8668749	255	13	main	main	ADJ
bjos-8668749	255	14	proteins	protein	NOUN
bjos-8668749	255	15	that	that	PRON
bjos-8668749	255	16	participate	participate	VERB
bjos-8668749	255	17	in	in	ADP
bjos-8668749	255	18	the	the	DET
bjos-8668749	255	19	anchoring	anchoring	NOUN
bjos-8668749	255	20	process	process	NOUN
bjos-8668749	255	21	between	between	ADP
bjos-8668749	255	22	the	the	DET
bjos-8668749	255	23	bone	bone	NOUN
bjos-8668749	255	24	tissue	tissue	NOUN
bjos-8668749	255	25	(	(	PUNCT
bjos-8668749	255	26	periosteum	periosteum	NOUN
bjos-8668749	255	27	)	)	PUNCT
bjos-8668749	255	28	and	and	CCONJ
bjos-8668749	255	29	the	the	DET
bjos-8668749	255	30	implant	implant	NOUN
bjos-8668749	255	31	.	.	PUNCT
bjos-8668749	256	1	integrin	integrin	NOUN
bjos-8668749	256	2	acts	act	VERB
bjos-8668749	256	3	as	as	ADP
bjos-8668749	256	4	a	a	DET
bjos-8668749	256	5	transmembrane	transmembrane	ADJ
bjos-8668749	256	6	mediator	mediator	NOUN
bjos-8668749	256	7	with	with	ADP
bjos-8668749	256	8	the	the	DET
bjos-8668749	256	9	protein	protein	NOUN
bjos-8668749	256	10	ligaments	ligament	NOUN
bjos-8668749	256	11	between	between	ADP
bjos-8668749	256	12	the	the	DET
bjos-8668749	256	13	two	two	NUM
bjos-8668749	256	14	interfaces	interface	NOUN
bjos-8668749	256	15	.	.	PUNCT
bjos-8668749	257	1	cell	cell	NOUN
bjos-8668749	257	2	-	-	PUNCT
bjos-8668749	257	3	protein	protein	NOUN
bjos-8668749	257	4	-	-	PUNCT
bjos-8668749	257	5	implant	implant	ADJ
bjos-8668749	257	6	interactions	interaction	NOUN
bjos-8668749	257	7	are	be	AUX
bjos-8668749	257	8	indispensable	indispensable	ADJ
bjos-8668749	257	9	for	for	ADP
bjos-8668749	257	10	understanding	understand	VERB
bjos-8668749	257	11	cellular	cellular	ADJ
bjos-8668749	257	12	responses	response	NOUN
bjos-8668749	257	13	to	to	ADP
bjos-8668749	257	14	implanted	implant	VERB
bjos-8668749	257	15	devices	device	NOUN
bjos-8668749	257	16	and	and	CCONJ
bjos-8668749	257	17	involving	involve	VERB
bjos-8668749	257	18	osseointegration	osseointegration	NOUN
bjos-8668749	257	19	.	.	PUNCT
bjos-8668749	258	1	while	while	SCONJ
bjos-8668749	258	2	fibronectin	fibronectin	NOUN
bjos-8668749	258	3	is	be	AUX
bjos-8668749	258	4	an	an	DET
bjos-8668749	258	5	adhesive	adhesive	ADJ
bjos-8668749	258	6	protein	protein	NOUN
bjos-8668749	258	7	that	that	PRON
bjos-8668749	258	8	can	can	AUX
bjos-8668749	258	9	mediate	mediate	VERB
bjos-8668749	258	10	adhesion	adhesion	NOUN
bjos-8668749	258	11	with	with	ADP
bjos-8668749	258	12	implants	implant	NOUN
bjos-8668749	258	13	,	,	PUNCT
bjos-8668749	258	14	this	this	PRON
bjos-8668749	258	15	is	be	AUX
bjos-8668749	258	16	through	through	ADP
bjos-8668749	258	17	integrins	integrin	NOUN
bjos-8668749	258	18	.	.	PUNCT
bjos-8668749	259	1	in	in	ADP
bjos-8668749	259	2	this	this	DET
bjos-8668749	259	3	way	way	NOUN
bjos-8668749	259	4	fibronectin	fibronectin	NOUN
bjos-8668749	259	5	is	be	AUX
bjos-8668749	259	6	able	able	ADJ
bjos-8668749	259	7	13	13	NUM
bjos-8668749	260	1	nascimento	nascimento	PROPN
bjos-8668749	260	2	et	et	PROPN
bjos-8668749	260	3	al	al	PROPN
bjos-8668749	260	4	.	.	PROPN
bjos-8668749	260	5	braz	braz	PROPN
bjos-8668749	260	6	j	j	PROPN
bjos-8668749	260	7	oral	oral	PROPN
bjos-8668749	260	8	sci	sci	PROPN
bjos-8668749	260	9	.	.	PUNCT
bjos-8668749	261	1	2023;22	2023;22	NUM
bjos-8668749	261	2	:	:	PUNCT
bjos-8668749	261	3	e238749	e238749	NOUN
bjos-8668749	261	4	to	to	PART
bjos-8668749	261	5	bind	bind	VERB
bjos-8668749	261	6	to	to	ADP
bjos-8668749	261	7	other	other	ADJ
bjos-8668749	261	8	molecules	molecule	NOUN
bjos-8668749	261	9	such	such	ADJ
bjos-8668749	261	10	as	as	ADP
bjos-8668749	261	11	collagen	collagen	NOUN
bjos-8668749	261	12	fibers	fiber	NOUN
bjos-8668749	261	13	.	.	PUNCT
bjos-8668749	262	1	therefore	therefore	ADV
bjos-8668749	262	2	,	,	PUNCT
bjos-8668749	262	3	the	the	DET
bjos-8668749	262	4	comprehension	comprehension	NOUN
bjos-8668749	262	5	is	be	AUX
bjos-8668749	262	6	that	that	SCONJ
bjos-8668749	262	7	the	the	DET
bjos-8668749	262	8	proteins	protein	NOUN
bjos-8668749	262	9	interaction	interaction	NOUN
bjos-8668749	262	10	mechanism	mechanism	NOUN
bjos-8668749	262	11	with	with	ADP
bjos-8668749	262	12	dental	dental	ADJ
bjos-8668749	262	13	implants	implant	NOUN
bjos-8668749	262	14	is	be	AUX
bjos-8668749	262	15	important	important	ADJ
bjos-8668749	262	16	for	for	ADP
bjos-8668749	262	17	a	a	DET
bjos-8668749	262	18	better	well	ADJ
bjos-8668749	262	19	understanding	understanding	NOUN
bjos-8668749	262	20	of	of	ADP
bjos-8668749	262	21	the	the	DET
bjos-8668749	262	22	osseointegration	osseointegration	NOUN
bjos-8668749	262	23	process	process	NOUN
bjos-8668749	262	24	,	,	PUNCT
bjos-8668749	262	25	and	and	CCONJ
bjos-8668749	262	26	thus	thus	ADV
bjos-8668749	262	27	,	,	PUNCT
bjos-8668749	262	28	a	a	DET
bjos-8668749	262	29	better	well	ADJ
bjos-8668749	262	30	planning	planning	NOUN
bjos-8668749	262	31	of	of	ADP
bjos-8668749	262	32	titanium	titanium	NOUN
bjos-8668749	262	33	osseointegrable	osseointegrable	ADJ
bjos-8668749	262	34	implants	implant	NOUN
bjos-8668749	262	35	.	.	PUNCT
bjos-8668749	263	1	acknowledgements	acknowledgement	NOUN
bjos-8668749	263	2	this	this	DET
bjos-8668749	263	3	work	work	NOUN
bjos-8668749	263	4	received	receive	VERB
bjos-8668749	263	5	no	no	DET
bjos-8668749	263	6	financial	financial	ADJ
bjos-8668749	263	7	support	support	NOUN
bjos-8668749	263	8	.	.	PUNCT
bjos-8668749	264	1	conflict	conflict	NOUN
bjos-8668749	264	2	of	of	ADP
bjos-8668749	264	3	interest	interest	NOUN
bjos-8668749	264	4	the	the	DET
bjos-8668749	264	5	authors	author	NOUN
bjos-8668749	264	6	have	have	VERB
bjos-8668749	264	7	no	no	DET
bjos-8668749	264	8	connections	connection	NOUN
bjos-8668749	264	9	or	or	CCONJ
bjos-8668749	264	10	conflicts	conflict	NOUN
bjos-8668749	264	11	of	of	ADP
bjos-8668749	264	12	interest	interest	NOUN
bjos-8668749	264	13	with	with	ADP
bjos-8668749	264	14	companies	company	NOUN
bjos-8668749	264	15	that	that	PRON
bjos-8668749	264	16	contributed	contribute	VERB
bjos-8668749	264	17	to	to	ADP
bjos-8668749	264	18	this	this	DET
bjos-8668749	264	19	article	article	NOUN
bjos-8668749	264	20	.	.	PUNCT
bjos-8668749	265	1	data	datum	NOUN
bjos-8668749	265	2	availability	availability	NOUN
bjos-8668749	265	3	the	the	DET
bjos-8668749	265	4	datasets	dataset	NOUN
bjos-8668749	265	5	related	relate	VERB
bjos-8668749	265	6	to	to	ADP
bjos-8668749	265	7	this	this	DET
bjos-8668749	265	8	article	article	NOUN
bjos-8668749	265	9	can	can	AUX
bjos-8668749	265	10	not	not	PART
bjos-8668749	265	11	be	be	AUX
bjos-8668749	265	12	shared	share	VERB
bjos-8668749	265	13	at	at	ADP
bjos-8668749	265	14	this	this	DET
bjos-8668749	265	15	time	time	NOUN
bjos-8668749	265	16	because	because	SCONJ
bjos-8668749	265	17	they	they	PRON
bjos-8668749	265	18	are	be	AUX
bjos-8668749	265	19	part	part	NOUN
bjos-8668749	265	20	of	of	ADP
bjos-8668749	265	21	ongoing	ongoing	ADJ
bjos-8668749	265	22	research	research	NOUN
bjos-8668749	265	23	.	.	PUNCT
bjos-8668749	266	1	authors	author	NOUN
bjos-8668749	266	2	contribution	contribution	VERB
bjos-8668749	266	3	marvin	marvin	PROPN
bjos-8668749	266	4	do	do	AUX
bjos-8668749	266	5	nascimento	nascimento	PROPN
bjos-8668749	266	6	:	:	PUNCT
bjos-8668749	266	7	reviewed	review	VERB
bjos-8668749	266	8	the	the	DET
bjos-8668749	266	9	literature	literature	NOUN
bjos-8668749	266	10	and	and	CCONJ
bjos-8668749	266	11	developed	develop	VERB
bjos-8668749	266	12	the	the	DET
bjos-8668749	266	13	topics	topic	NOUN
bjos-8668749	266	14	worked	work	VERB
bjos-8668749	266	15	on	on	ADP
bjos-8668749	266	16	in	in	ADP
bjos-8668749	266	17	the	the	DET
bjos-8668749	266	18	manuscript	manuscript	NOUN
bjos-8668749	266	19	as	as	ADV
bjos-8668749	266	20	well	well	ADV
bjos-8668749	266	21	as	as	ADP
bjos-8668749	266	22	the	the	DET
bjos-8668749	266	23	figures	figure	NOUN
bjos-8668749	266	24	,	,	PUNCT
bjos-8668749	266	25	reviewed	review	VERB
bjos-8668749	266	26	and	and	CCONJ
bjos-8668749	266	27	approved	approve	VERB
bjos-8668749	266	28	the	the	DET
bjos-8668749	266	29	final	final	ADJ
bjos-8668749	266	30	version	version	NOUN
bjos-8668749	266	31	.	.	PUNCT
bjos-8668749	267	1	thays	thay	VERB
bjos-8668749	267	2	obando	obando	PROPN
bjos-8668749	267	3	brito	brito	PROPN
bjos-8668749	267	4	:	:	PUNCT
bjos-8668749	267	5	acted	act	VERB
bjos-8668749	267	6	in	in	ADP
bjos-8668749	267	7	the	the	DET
bjos-8668749	267	8	search	search	NOUN
bjos-8668749	267	9	for	for	ADP
bjos-8668749	267	10	the	the	DET
bjos-8668749	267	11	review	review	NOUN
bjos-8668749	267	12	of	of	ADP
bjos-8668749	267	13	the	the	DET
bjos-8668749	267	14	findings	finding	NOUN
bjos-8668749	267	15	,	,	PUNCT
bjos-8668749	267	16	reviewed	review	VERB
bjos-8668749	267	17	and	and	CCONJ
bjos-8668749	267	18	approved	approve	VERB
bjos-8668749	267	19	the	the	DET
bjos-8668749	267	20	final	final	ADJ
bjos-8668749	267	21	version	version	NOUN
bjos-8668749	267	22	of	of	ADP
bjos-8668749	267	23	the	the	DET
bjos-8668749	267	24	manuscript	manuscript	NOUN
bjos-8668749	267	25	.	.	PUNCT
bjos-8668749	268	1	andreza	andreza	PROPN
bjos-8668749	268	2	menezes	menezes	PROPN
bjos-8668749	268	3	lima	lima	PROPN
bjos-8668749	268	4	:	:	PUNCT
bjos-8668749	268	5	assisted	assist	VERB
bjos-8668749	268	6	in	in	ADP
bjos-8668749	268	7	the	the	DET
bjos-8668749	268	8	search	search	NOUN
bjos-8668749	268	9	for	for	ADP
bjos-8668749	268	10	the	the	DET
bjos-8668749	268	11	review	review	NOUN
bjos-8668749	268	12	of	of	ADP
bjos-8668749	268	13	findings	finding	NOUN
bjos-8668749	268	14	,	,	PUNCT
bjos-8668749	268	15	and	and	CCONJ
bjos-8668749	268	16	reviewed	review	VERB
bjos-8668749	268	17	and	and	CCONJ
bjos-8668749	268	18	approved	approve	VERB
bjos-8668749	268	19	the	the	DET
bjos-8668749	268	20	final	final	ADJ
bjos-8668749	268	21	version	version	NOUN
bjos-8668749	268	22	of	of	ADP
bjos-8668749	268	23	the	the	DET
bjos-8668749	268	24	manuscript	manuscript	NOUN
bjos-8668749	268	25	.	.	PUNCT
bjos-8668749	269	1	carlos	carlos	PROPN
bjos-8668749	269	2	nelson	nelson	PROPN
bjos-8668749	269	3	elias	elias	PROPN
bjos-8668749	269	4	:	:	PUNCT
bjos-8668749	269	5	guided	guide	VERB
bjos-8668749	269	6	the	the	DET
bjos-8668749	269	7	structuring	structuring	NOUN
bjos-8668749	269	8	of	of	ADP
bjos-8668749	269	9	the	the	DET
bjos-8668749	269	10	content	content	NOUN
bjos-8668749	269	11	,	,	PUNCT
bjos-8668749	269	12	helped	help	VERB
bjos-8668749	269	13	in	in	ADP
bjos-8668749	269	14	the	the	DET
bjos-8668749	269	15	development	development	NOUN
bjos-8668749	269	16	of	of	ADP
bjos-8668749	269	17	the	the	DET
bjos-8668749	269	18	manuscript	manuscript	NOUN
bjos-8668749	269	19	,	,	PUNCT
bjos-8668749	269	20	and	and	CCONJ
bjos-8668749	269	21	reviewed	review	VERB
bjos-8668749	269	22	and	and	CCONJ
bjos-8668749	269	23	approved	approve	VERB
bjos-8668749	269	24	the	the	DET
bjos-8668749	269	25	final	final	ADJ
bjos-8668749	269	26	version	version	NOUN
bjos-8668749	269	27	of	of	ADP
bjos-8668749	269	28	the	the	DET
bjos-8668749	269	29	manuscript	manuscript	NOUN
bjos-8668749	269	30	.	.	PUNCT
bjos-8668749	270	1	references	reference	NOUN
bjos-8668749	270	2	1	1	NUM
bjos-8668749	270	3	.	.	PUNCT
bjos-8668749	270	4	alkhaibary	alkhaibary	PROPN
bjos-8668749	270	5	a	a	X
bjos-8668749	270	6	,	,	PUNCT
bjos-8668749	270	7	alharbi	alharbi	NOUN
bjos-8668749	270	8	a	a	PRON
bjos-8668749	270	9	,	,	PUNCT
bjos-8668749	270	10	alnefaie	alnefaie	PROPN
bjos-8668749	270	11	n	n	CCONJ
bjos-8668749	270	12	,	,	PUNCT
bjos-8668749	270	13	oqallaa	oqallaa	PROPN
bjos-8668749	270	14	almubarak	almubarak	PROPN
bjos-8668749	270	15	a	a	PROPN
bjos-8668749	270	16	,	,	PUNCT
bjos-8668749	270	17	aloraidi	aloraidi	NOUN
bjos-8668749	270	18	a	a	X
bjos-8668749	270	19	,	,	PUNCT
bjos-8668749	270	20	khairy	khairy	PROPN
bjos-8668749	270	21	s.	s.	PROPN
bjos-8668749	270	22	cranioplasty	cranioplasty	PROPN
bjos-8668749	270	23	:	:	PUNCT
bjos-8668749	270	24	a	a	DET
bjos-8668749	270	25	comprehensive	comprehensive	ADJ
bjos-8668749	270	26	review	review	NOUN
bjos-8668749	270	27	of	of	ADP
bjos-8668749	270	28	the	the	DET
bjos-8668749	270	29	history	history	NOUN
bjos-8668749	270	30	,	,	PUNCT
bjos-8668749	270	31	materials	material	NOUN
bjos-8668749	270	32	,	,	PUNCT
bjos-8668749	270	33	surgical	surgical	ADJ
bjos-8668749	270	34	aspects	aspect	NOUN
bjos-8668749	270	35	,	,	PUNCT
bjos-8668749	270	36	and	and	CCONJ
bjos-8668749	270	37	complications	complication	NOUN
bjos-8668749	270	38	.	.	PUNCT
bjos-8668749	271	1	world	world	PROPN
bjos-8668749	271	2	neurosurg	neurosurg	PROPN
bjos-8668749	271	3	.	.	PUNCT
bjos-8668749	272	1	2020	2020	NUM
bjos-8668749	272	2	jul;139:445	jul;139:445	NOUN
bjos-8668749	272	3	-	-	PUNCT
bjos-8668749	272	4	52	52	NUM
bjos-8668749	272	5	.	.	PUNCT
bjos-8668749	273	1	doi	doi	NOUN
bjos-8668749	273	2	:	:	PUNCT
bjos-8668749	273	3	10.1016	10.1016	NUM
bjos-8668749	273	4	/	/	SYM
bjos-8668749	273	5	j.wneu.2020.04.211	j.wneu.2020.04.211	PROPN
bjos-8668749	273	6	.	.	PUNCT
bjos-8668749	274	1	2	2	X
bjos-8668749	274	2	.	.	X
bjos-8668749	274	3	insua	insua	PROPN
bjos-8668749	274	4	a	a	PROPN
bjos-8668749	274	5	,	,	PUNCT
bjos-8668749	274	6	monje	monje	PROPN
bjos-8668749	274	7	a	a	PROPN
bjos-8668749	274	8	,	,	PUNCT
bjos-8668749	274	9	wang	wang	PROPN
bjos-8668749	274	10	h	h	PROPN
bjos-8668749	274	11	-	-	PUNCT
bjos-8668749	274	12	l	l	NOUN
bjos-8668749	274	13	,	,	PUNCT
bjos-8668749	274	14	miron	miron	PROPN
bjos-8668749	274	15	rj	rj	PROPN
bjos-8668749	274	16	.	.	PUNCT
bjos-8668749	274	17	basis	basis	NOUN
bjos-8668749	274	18	of	of	ADP
bjos-8668749	274	19	bone	bone	NOUN
bjos-8668749	274	20	metabolism	metabolism	NOUN
bjos-8668749	274	21	around	around	ADP
bjos-8668749	274	22	dental	dental	ADJ
bjos-8668749	274	23	implants	implant	NOUN
bjos-8668749	274	24	during	during	ADP
bjos-8668749	274	25	osseointegration	osseointegration	NOUN
bjos-8668749	274	26	and	and	CCONJ
bjos-8668749	274	27	peri	peri	NOUN
bjos-8668749	274	28	-	-	PUNCT
bjos-8668749	274	29	implant	implant	ADJ
bjos-8668749	274	30	bone	bone	NOUN
bjos-8668749	274	31	loss	loss	NOUN
bjos-8668749	274	32	.	.	PUNCT
bjos-8668749	275	1	j	j	PROPN
bjos-8668749	275	2	biomed	biome	VERB
bjos-8668749	275	3	mater	mater	NOUN
bjos-8668749	275	4	res	re	NOUN
bjos-8668749	275	5	part	part	NOUN
bjos-8668749	275	6	a.	a.	NOUN
bjos-8668749	275	7	2017	2017	NUM
bjos-8668749	275	8	jul;105(7):2075	jul;105(7):2075	PROPN
bjos-8668749	275	9	-	-	PUNCT
bjos-8668749	275	10	89	89	NUM
bjos-8668749	275	11	.	.	PUNCT
bjos-8668749	276	1	doi	doi	NOUN
bjos-8668749	276	2	:	:	PUNCT
bjos-8668749	276	3	10.1002	10.1002	NUM
bjos-8668749	276	4	/	/	SYM
bjos-8668749	276	5	jbm.a.36060	jbm.a.36060	NOUN
bjos-8668749	276	6	.	.	NOUN
bjos-8668749	277	1	3	3	X
bjos-8668749	277	2	.	.	X
bjos-8668749	278	1	elias	elias	PROPN
bjos-8668749	278	2	cn	cn	PROPN
bjos-8668749	278	3	,	,	PUNCT
bjos-8668749	278	4	gravina	gravina	PROPN
bjos-8668749	278	5	pa	pa	PROPN
bjos-8668749	278	6	,	,	PUNCT
bjos-8668749	278	7	busquim	busquim	PROPN
bjos-8668749	278	8	tp	tp	NOUN
bjos-8668749	278	9	,	,	PUNCT
bjos-8668749	278	10	kuri	kuri	PROPN
bjos-8668749	278	11	se	se	PROPN
bjos-8668749	278	12	,	,	PUNCT
bjos-8668749	278	13	silva	silva	PROPN
bjos-8668749	278	14	fc	fc	PROPN
bjos-8668749	278	15	.	.	PUNCT
bjos-8668749	279	1	[	[	X
bjos-8668749	279	2	biomimicry	biomimicry	NOUN
bjos-8668749	279	3	of	of	ADP
bjos-8668749	279	4	the	the	DET
bjos-8668749	279	5	surface	surface	NOUN
bjos-8668749	279	6	of	of	ADP
bjos-8668749	279	7	dental	dental	ADJ
bjos-8668749	279	8	implants	implant	NOUN
bjos-8668749	279	9	]	]	PUNCT
bjos-8668749	279	10	.	.	PUNCT
bjos-8668749	280	1	implantnews	implantnews	PROPN
bjos-8668749	280	2	.	.	PUNCT
bjos-8668749	281	1	2011;8(3b	2011;8(3b	NUM
bjos-8668749	281	2	-	-	PUNCT
bjos-8668749	281	3	pba	pba	NOUN
bjos-8668749	281	4	)	)	PUNCT
bjos-8668749	281	5	p47	p47	PROPN
bjos-8668749	281	6	-	-	PUNCT
bjos-8668749	281	7	55	55	NUM
bjos-8668749	281	8	.	.	PUNCT
bjos-8668749	282	1	portuguese	portuguese	ADJ
bjos-8668749	282	2	.	.	PUNCT
bjos-8668749	283	1	4	4	X
bjos-8668749	283	2	.	.	X
bjos-8668749	283	3	mendes	mende	NOUN
bjos-8668749	283	4	vc	vc	PROPN
bjos-8668749	283	5	,	,	PUNCT
bjos-8668749	283	6	davies	davies	PROPN
bjos-8668749	283	7	je	je	PROPN
bjos-8668749	283	8	.	.	PUNCT
bjos-8668749	284	1	[	[	X
bjos-8668749	284	2	a	a	DET
bjos-8668749	284	3	new	new	ADJ
bjos-8668749	284	4	perspective	perspective	NOUN
bjos-8668749	284	5	in	in	ADP
bjos-8668749	284	6	the	the	DET
bjos-8668749	284	7	biology	biology	NOUN
bjos-8668749	284	8	of	of	ADP
bjos-8668749	284	9	osseointegration	osseointegration	NOUN
bjos-8668749	284	10	]	]	PUNCT
bjos-8668749	284	11	.	.	PUNCT
bjos-8668749	285	1	rev	rev	PROPN
bjos-8668749	285	2	assoc	assoc	PROPN
bjos-8668749	285	3	paul	paul	PROPN
bjos-8668749	285	4	cir	cir	PROPN
bjos-8668749	285	5	dent	dent	PROPN
bjos-8668749	285	6	.	.	PUNCT
bjos-8668749	286	1	2016;70(2):166	2016;70(2):166	NUM
bjos-8668749	286	2	-	-	SYM
bjos-8668749	286	3	71	71	NUM
bjos-8668749	286	4	.	.	PUNCT
bjos-8668749	287	1	portuguese	portuguese	ADJ
bjos-8668749	287	2	.	.	PUNCT
bjos-8668749	288	1	5	5	X
bjos-8668749	288	2	.	.	X
bjos-8668749	288	3	nakahama	nakahama	NOUN
bjos-8668749	288	4	k.	k.	PROPN
bjos-8668749	288	5	cellular	cellular	PROPN
bjos-8668749	288	6	communications	communication	NOUN
bjos-8668749	288	7	in	in	ADP
bjos-8668749	288	8	bone	bone	NOUN
bjos-8668749	288	9	homeostasis	homeostasis	NOUN
bjos-8668749	288	10	and	and	CCONJ
bjos-8668749	288	11	repair	repair	NOUN
bjos-8668749	288	12	.	.	PUNCT
bjos-8668749	289	1	cell	cell	NOUN
bjos-8668749	289	2	mol	mol	ADP
bjos-8668749	289	3	life	life	PROPN
bjos-8668749	289	4	sci	sci	PROPN
bjos-8668749	289	5	.	.	PROPN
bjos-8668749	289	6	2010	2010	NUM
bjos-8668749	289	7	dec;67(23):4001	dec;67(23):4001	NOUN
bjos-8668749	289	8	-	-	SYM
bjos-8668749	289	9	9	9	NUM
bjos-8668749	289	10	.	.	PUNCT
bjos-8668749	289	11	doi	doi	NOUN
bjos-8668749	289	12	:	:	PUNCT
bjos-8668749	289	13	10.1007	10.1007	NUM
bjos-8668749	289	14	/	/	SYM
bjos-8668749	289	15	s00018	s00018	NOUN
bjos-8668749	289	16	-	-	PUNCT
bjos-8668749	289	17	010	010	NUM
bjos-8668749	289	18	-	-	PUNCT
bjos-8668749	289	19	0479	0479	NUM
bjos-8668749	289	20	-	-	PUNCT
bjos-8668749	289	21	3	3	NUM
bjos-8668749	289	22	.	.	NOUN
bjos-8668749	289	23	6	6	NUM
bjos-8668749	289	24	.	.	PUNCT
bjos-8668749	290	1	elias	elias	PROPN
bjos-8668749	290	2	cn	cn	PROPN
bjos-8668749	290	3	,	,	PUNCT
bjos-8668749	290	4	meirelles	meirelles	PROPN
bjos-8668749	290	5	l.	l.	PROPN
bjos-8668749	290	6	 	 	SPACE
bjos-8668749	290	7	improving	improve	VERB
bjos-8668749	290	8	osseointegration	osseointegration	NOUN
bjos-8668749	290	9	of	of	ADP
bjos-8668749	290	10	dental	dental	ADJ
bjos-8668749	290	11	implants	implant	NOUN
bjos-8668749	290	12	.	.	PUNCT
bjos-8668749	291	1	expert	expert	NOUN
bjos-8668749	291	2	rev	rev	VERB
bjos-8668749	291	3	med	med	PROPN
bjos-8668749	291	4	devices	device	NOUN
bjos-8668749	291	5	.	.	PUNCT
bjos-8668749	292	1	2010	2010	NUM
bjos-8668749	292	2	mar;7(2):241	mar;7(2):241	PROPN
bjos-8668749	292	3	-	-	PROPN
bjos-8668749	292	4	56	56	NUM
bjos-8668749	292	5	.	.	PUNCT
bjos-8668749	293	1	doi	doi	NOUN
bjos-8668749	293	2	:	:	PUNCT
bjos-8668749	293	3	10.1586	10.1586	NUM
bjos-8668749	293	4	/	/	SYM
bjos-8668749	293	5	erd.09.74	erd.09.74	ADJ
bjos-8668749	293	6	.	.	PUNCT
bjos-8668749	293	7	  	  	SPACE
bjos-8668749	293	8	7	7	NUM
bjos-8668749	293	9	.	.	PUNCT
bjos-8668749	294	1	rabe	rabe	PROPN
bjos-8668749	294	2	m	m	PROPN
bjos-8668749	294	3	,	,	PUNCT
bjos-8668749	294	4	verdes	verdes	PROPN
bjos-8668749	294	5	d	d	PROPN
bjos-8668749	294	6	,	,	PUNCT
bjos-8668749	294	7	seeger	seeger	PROPN
bjos-8668749	294	8	s.	s.	PROPN
bjos-8668749	294	9	understanding	understand	VERB
bjos-8668749	294	10	protein	protein	NOUN
bjos-8668749	294	11	adsorption	adsorption	NOUN
bjos-8668749	294	12	phenomena	phenomenon	NOUN
bjos-8668749	294	13	at	at	ADP
bjos-8668749	294	14	solid	solid	ADJ
bjos-8668749	294	15	surfaces	surface	NOUN
bjos-8668749	294	16	.	.	PUNCT
bjos-8668749	295	1	adv	adv	PROPN
bjos-8668749	295	2	colloid	colloid	PROPN
bjos-8668749	295	3	interface	interface	NOUN
bjos-8668749	295	4	sci	sci	PROPN
bjos-8668749	295	5	.	.	PROPN
bjos-8668749	295	6	2011	2011	NUM
bjos-8668749	296	1	feb;162(1	feb;162(1	ADV
bjos-8668749	296	2	-	-	SYM
bjos-8668749	296	3	2):87	2):87	NUM
bjos-8668749	296	4	-	-	PUNCT
bjos-8668749	296	5	106	106	NUM
bjos-8668749	296	6	.	.	PUNCT
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bjos-8668749	297	2	:	:	PUNCT
bjos-8668749	297	3	10.1016	10.1016	NUM
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bjos-8668749	297	6	.	.	PUNCT
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bjos-8668749	298	4	al	al	PROPN
bjos-8668749	298	5	.	.	PROPN
bjos-8668749	298	6	braz	braz	PROPN
bjos-8668749	298	7	j	j	PROPN
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bjos-8668749	298	10	.	.	PUNCT
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bjos-8668749	299	2	:	:	PUNCT
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bjos-8668749	299	5	.	.	PUNCT
bjos-8668749	300	1	helfrich	helfrich	PROPN
bjos-8668749	300	2	mh	mh	PROPN
bjos-8668749	300	3	,	,	PUNCT
bjos-8668749	300	4	stenbeck	stenbeck	NOUN
bjos-8668749	300	5	g	g	PROPN
bjos-8668749	300	6	,	,	PUNCT
bjos-8668749	300	7	nesbitt	nesbitt	PROPN
bjos-8668749	300	8	sa	sa	PROPN
bjos-8668749	300	9	,	,	PUNCT
bjos-8668749	300	10	horton	horton	PROPN
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bjos-8668749	300	12	.	.	PROPN
bjos-8668749	300	13	integrins	integrin	NOUN
bjos-8668749	300	14	and	and	CCONJ
bjos-8668749	300	15	adhesion	adhesion	NOUN
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bjos-8668749	300	17	.	.	PUNCT
bjos-8668749	301	1	in	in	ADP
bjos-8668749	301	2	:	:	PUNCT
bjos-8668749	301	3	bilezikan	bilezikan	PROPN
bjos-8668749	301	4	jp	jp	PROPN
bjos-8668749	301	5	,	,	PUNCT
bjos-8668749	301	6	raisz	raisz	ADJ
bjos-8668749	301	7	lg	lg	PROPN
bjos-8668749	301	8	,	,	PUNCT
bjos-8668749	301	9	martin	martin	PROPN
bjos-8668749	301	10	tj	tj	PROPN
bjos-8668749	301	11	,	,	PUNCT
bjos-8668749	301	12	editors	editor	NOUN
bjos-8668749	301	13	.	.	PUNCT
bjos-8668749	301	14	 	 	SPACE
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bjos-8668749	301	17	bone	bone	NOUN
bjos-8668749	301	18	biology	biology	NOUN
bjos-8668749	301	19	.	.	PUNCT
bjos-8668749	301	20	 	 	SPACE
bjos-8668749	301	21	san	san	PROPN
bjos-8668749	301	22	diego	diego	PROPN
bjos-8668749	301	23	,	,	PUNCT
bjos-8668749	301	24	calif	calif	PROPN
bjos-8668749	301	25	,	,	PUNCT
bjos-8668749	301	26	usa	usa	PROPN
bjos-8668749	301	27	:	:	PUNCT
bjos-8668749	301	28	academic	academic	ADJ
bjos-8668749	301	29	press	press	NOUN
bjos-8668749	301	30	,	,	PUNCT
bjos-8668749	301	31	elsevier	elsevier	NOUN
bjos-8668749	301	32	;	;	PUNCT
bjos-8668749	301	33	2008	2008	NUM
bjos-8668749	301	34	.	.	PUNCT
bjos-8668749	302	1	vol.1	vol.1	ADV
bjos-8668749	302	2	,	,	PUNCT
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bjos-8668749	302	5	424	424	NUM
bjos-8668749	302	6	.	.	NOUN
bjos-8668749	303	1	9	9	NUM
bjos-8668749	303	2	.	.	X
bjos-8668749	303	3	brånemark	brånemark	PROPN
bjos-8668749	303	4	pi	pi	PROPN
bjos-8668749	303	5	.	.	PUNCT
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bjos-8668749	304	2	and	and	CCONJ
bjos-8668749	304	3	its	its	PRON
bjos-8668749	304	4	experimental	experimental	ADJ
bjos-8668749	304	5	background	background	NOUN
bjos-8668749	304	6	.	.	PUNCT
bjos-8668749	305	1	j	j	PROPN
bjos-8668749	305	2	prosthet	prosthet	PROPN
bjos-8668749	305	3	dent	dent	PROPN
bjos-8668749	305	4	.	.	PUNCT
bjos-8668749	306	1	1983	1983	NUM
bjos-8668749	306	2	sep;50(3):399	sep;50(3):399	PROPN
bjos-8668749	306	3	-	-	PUNCT
bjos-8668749	306	4	410	410	NUM
bjos-8668749	306	5	.	.	PUNCT
bjos-8668749	307	1	doi	doi	NOUN
bjos-8668749	307	2	:	:	PUNCT
bjos-8668749	307	3	10.1016	10.1016	NUM
bjos-8668749	307	4	/	/	SYM
bjos-8668749	307	5	s0022	s0022	NOUN
bjos-8668749	307	6	-	-	PUNCT
bjos-8668749	307	7	3913(83)80101	3913(83)80101	NUM
bjos-8668749	307	8	-	-	SYM
bjos-8668749	307	9	2	2	NUM
bjos-8668749	307	10	.	.	NOUN
bjos-8668749	307	11	10	10	NUM
bjos-8668749	307	12	.	.	PUNCT
bjos-8668749	308	1	letić	letić	ADJ
bjos-8668749	308	2	-	-	PUNCT
bjos-8668749	308	3	gavrilović	gavrilović	NOUN
bjos-8668749	308	4	a	a	PRON
bjos-8668749	308	5	,	,	PUNCT
bjos-8668749	308	6	scandurra	scandurra	NOUN
bjos-8668749	308	7	r	r	NOUN
bjos-8668749	308	8	,	,	PUNCT
bjos-8668749	308	9	abe	abe	PROPN
bjos-8668749	308	10	k.	k.	PROPN
bjos-8668749	309	1	genetic	genetic	ADJ
bjos-8668749	309	2	potential	potential	NOUN
bjos-8668749	309	3	of	of	ADP
bjos-8668749	309	4	interfacial	interfacial	ADJ
bjos-8668749	309	5	guided	guide	VERB
bjos-8668749	309	6	osteogenesis	osteogenesis	NOUN
bjos-8668749	309	7	in	in	ADP
bjos-8668749	309	8	implant	implant	ADJ
bjos-8668749	309	9	devices	device	NOUN
bjos-8668749	309	10	.	.	PUNCT
bjos-8668749	310	1	dent	dent	NOUN
bjos-8668749	310	2	mater	mater	NOUN
bjos-8668749	310	3	j.	j.	PROPN
bjos-8668749	310	4	2000	2000	NUM
bjos-8668749	310	5	jun;19(2):99	jun;19(2):99	PROPN
bjos-8668749	310	6	-	-	PUNCT
bjos-8668749	310	7	132	132	NUM
bjos-8668749	310	8	.	.	PUNCT
bjos-8668749	311	1	doi	doi	NOUN
bjos-8668749	311	2	:	:	PUNCT
bjos-8668749	311	3	10.4012	10.4012	NUM
bjos-8668749	311	4	/	/	SYM
bjos-8668749	311	5	dmj.19.99	dmj.19.99	NOUN
bjos-8668749	311	6	.	.	PUNCT
bjos-8668749	312	1	11	11	NUM
bjos-8668749	312	2	.	.	PUNCT
bjos-8668749	313	1	davies	davies	PROPN
bjos-8668749	313	2	je	je	PROPN
bjos-8668749	313	3	.	.	PUNCT
bjos-8668749	313	4	mechanisms	mechanism	NOUN
bjos-8668749	313	5	of	of	ADP
bjos-8668749	313	6	endosseous	endosseous	ADJ
bjos-8668749	313	7	integration	integration	NOUN
bjos-8668749	313	8	.	.	PUNCT
bjos-8668749	314	1	int	int	NOUN
bjos-8668749	314	2	j	j	PROPN
bjos-8668749	314	3	prosthodont	prosthodont	PROPN
bjos-8668749	314	4	.	.	PUNCT
bjos-8668749	315	1	1998	1998	NUM
bjos-8668749	315	2	sep	sep	PROPN
bjos-8668749	315	3	-	-	PUNCT
bjos-8668749	315	4	oct;11(5):391	oct;11(5):391	NOUN
bjos-8668749	315	5	-	-	PUNCT
bjos-8668749	315	6	401	401	NUM
bjos-8668749	315	7	.	.	PUNCT
bjos-8668749	316	1	12	12	NUM
bjos-8668749	316	2	.	.	PUNCT
bjos-8668749	317	1	davies	davies	PROPN
bjos-8668749	317	2	je	je	PROPN
bjos-8668749	317	3	.	.	PUNCT
bjos-8668749	318	1	understanding	understand	VERB
bjos-8668749	318	2	peri	peri	NOUN
bjos-8668749	318	3	-	-	PUNCT
bjos-8668749	318	4	implant	implant	ADJ
bjos-8668749	318	5	endosseous	endosseous	ADJ
bjos-8668749	318	6	healing	healing	NOUN
bjos-8668749	318	7	.	.	PUNCT
bjos-8668749	319	1	j	j	PROPN
bjos-8668749	319	2	dent	dent	PROPN
bjos-8668749	319	3	educ	educ	PROPN
bjos-8668749	319	4	.	.	PUNCT
bjos-8668749	320	1	2003	2003	NUM
bjos-8668749	320	2	aug;67(8):932	aug;67(8):932	NUM
bjos-8668749	320	3	-	-	SYM
bjos-8668749	320	4	49	49	NUM
bjos-8668749	320	5	.	.	PUNCT
bjos-8668749	321	1	13	13	NUM
bjos-8668749	321	2	.	.	PUNCT
bjos-8668749	322	1	davies	davies	PROPN
bjos-8668749	322	2	je	je	PROPN
bjos-8668749	322	3	.	.	PUNCT
bjos-8668749	322	4	bone	bone	NOUN
bjos-8668749	322	5	bonding	bonding	NOUN
bjos-8668749	322	6	at	at	ADP
bjos-8668749	322	7	natural	natural	ADJ
bjos-8668749	322	8	and	and	CCONJ
bjos-8668749	322	9	biomaterial	biomaterial	ADJ
bjos-8668749	322	10	surfaces	surface	NOUN
bjos-8668749	322	11	.	.	PUNCT
bjos-8668749	322	12	biomaterials	biomaterial	NOUN
bjos-8668749	322	13	.	.	PUNCT
bjos-8668749	323	1	2007	2007	NUM
bjos-8668749	323	2	dec;28(34):5058	dec;28(34):5058	NOUN
bjos-8668749	323	3	-	-	PUNCT
bjos-8668749	323	4	67	67	NUM
bjos-8668749	323	5	.	.	PUNCT
bjos-8668749	324	1	doi	doi	NOUN
bjos-8668749	324	2	:	:	PUNCT
bjos-8668749	324	3	10.1016	10.1016	NUM
bjos-8668749	324	4	/	/	SYM
bjos-8668749	324	5	j.biomaterials.2007.07.049	j.biomaterials.2007.07.049	PROPN
bjos-8668749	324	6	.	.	PUNCT
bjos-8668749	325	1	14	14	NUM
bjos-8668749	325	2	.	.	PUNCT
bjos-8668749	326	1	anselme	anselme	PROPN
bjos-8668749	326	2	k.	k.	PROPN
bjos-8668749	327	1	osteoblast	osteoblast	VERB
bjos-8668749	327	2	adhesion	adhesion	NOUN
bjos-8668749	327	3	on	on	ADP
bjos-8668749	327	4	biomaterials	biomaterial	NOUN
bjos-8668749	327	5	.	.	PUNCT
bjos-8668749	328	1	biomaterials	biomaterial	NOUN
bjos-8668749	328	2	.	.	PUNCT
bjos-8668749	329	1	2000	2000	NUM
bjos-8668749	329	2	apr;21(7):667	apr;21(7):667	NUM
bjos-8668749	329	3	-	-	PUNCT
bjos-8668749	329	4	81	81	NUM
bjos-8668749	329	5	.	.	PUNCT
bjos-8668749	330	1	doi	doi	NOUN
bjos-8668749	330	2	:	:	PUNCT
bjos-8668749	330	3	10.1016	10.1016	NUM
bjos-8668749	330	4	/	/	SYM
bjos-8668749	330	5	s0142	s0142	NOUN
bjos-8668749	330	6	-	-	PUNCT
bjos-8668749	330	7	9612(99)00242	9612(99)00242	NOUN
bjos-8668749	330	8	-	-	PUNCT
bjos-8668749	330	9	2	2	NUM
bjos-8668749	330	10	.	.	NOUN
bjos-8668749	330	11	15	15	NUM
bjos-8668749	330	12	.	.	PUNCT
bjos-8668749	331	1	scotchford	scotchford	PROPN
bjos-8668749	331	2	ca	ca	PROPN
bjos-8668749	331	3	,	,	PUNCT
bjos-8668749	331	4	ball	ball	PROPN
bjos-8668749	331	5	m	m	PROPN
bjos-8668749	331	6	,	,	PUNCT
bjos-8668749	331	7	winkelmann	winkelmann	PROPN
bjos-8668749	331	8	m	m	PROPN
bjos-8668749	331	9	,	,	PUNCT
bjos-8668749	331	10	vörös	vörös	PROPN
bjos-8668749	331	11	j	j	PROPN
bjos-8668749	331	12	,	,	PUNCT
bjos-8668749	331	13	csucs	csucs	PROPN
bjos-8668749	331	14	c	c	PROPN
bjos-8668749	331	15	,	,	PUNCT
bjos-8668749	331	16	brunette	brunette	NOUN
bjos-8668749	331	17	dm	dm	PROPN
bjos-8668749	331	18	,	,	PUNCT
bjos-8668749	331	19	et	et	PROPN
bjos-8668749	331	20	al	al	PROPN
bjos-8668749	331	21	.	.	PROPN
bjos-8668749	331	22	chemically	chemically	ADV
bjos-8668749	331	23	patterned	pattern	VERB
bjos-8668749	331	24	,	,	PUNCT
bjos-8668749	331	25	metal	metal	NOUN
bjos-8668749	331	26	-	-	PUNCT
bjos-8668749	331	27	oxide	oxide	NOUN
bjos-8668749	331	28	-	-	PUNCT
bjos-8668749	331	29	based	base	VERB
bjos-8668749	331	30	surfaces	surface	NOUN
bjos-8668749	331	31	produced	produce	VERB
bjos-8668749	331	32	by	by	ADP
bjos-8668749	331	33	photolithographic	photolithographic	ADJ
bjos-8668749	331	34	techniques	technique	NOUN
bjos-8668749	331	35	for	for	ADP
bjos-8668749	331	36	studying	study	VERB
bjos-8668749	331	37	protein	protein	NOUN
bjos-8668749	331	38	and	and	CCONJ
bjos-8668749	331	39	cell	cell	NOUN
bjos-8668749	331	40	-	-	PUNCT
bjos-8668749	331	41	interactions	interaction	NOUN
bjos-8668749	331	42	.	.	PUNCT
bjos-8668749	332	1	ii	ii	NOUN
bjos-8668749	332	2	:	:	PUNCT
bjos-8668749	332	3	protein	protein	NOUN
bjos-8668749	332	4	adsorption	adsorption	NOUN
bjos-8668749	332	5	and	and	CCONJ
bjos-8668749	332	6	early	early	ADJ
bjos-8668749	332	7	cell	cell	NOUN
bjos-8668749	332	8	interactions	interaction	NOUN
bjos-8668749	332	9	.	.	PUNCT
bjos-8668749	333	1	biomaterials	biomaterial	NOUN
bjos-8668749	333	2	.	.	PUNCT
bjos-8668749	334	1	2003	2003	NUM
bjos-8668749	334	2	mar;24(7):1147	mar;24(7):1147	PROPN
bjos-8668749	334	3	-	-	PUNCT
bjos-8668749	334	4	58	58	NUM
bjos-8668749	334	5	.	.	PUNCT
bjos-8668749	335	1	doi	doi	NOUN
bjos-8668749	335	2	:	:	PUNCT
bjos-8668749	335	3	10.1016	10.1016	NUM
bjos-8668749	335	4	/	/	SYM
bjos-8668749	335	5	s0142	s0142	PRON
bjos-8668749	335	6	-	-	PUNCT
bjos-8668749	335	7	9612(02)00488	9612(02)00488	NUM
bjos-8668749	335	8	-	-	PUNCT
bjos-8668749	335	9	x.	x.	NOUN
bjos-8668749	335	10	16	16	NUM
bjos-8668749	335	11	.	.	PUNCT
bjos-8668749	336	1	steele	steele	PROPN
bjos-8668749	336	2	jg	jg	PROPN
bjos-8668749	336	3	,	,	PUNCT
bjos-8668749	336	4	mcfarland	mcfarland	PROPN
bjos-8668749	336	5	c	c	PROPN
bjos-8668749	336	6	,	,	PUNCT
bjos-8668749	336	7	dalton	dalton	PROPN
bjos-8668749	336	8	ba	ba	PROPN
bjos-8668749	336	9	,	,	PUNCT
bjos-8668749	336	10	johnson	johnson	PROPN
bjos-8668749	336	11	g	g	PROPN
bjos-8668749	336	12	,	,	PUNCT
bjos-8668749	336	13	evans	evans	PROPN
bjos-8668749	336	14	md	md	PROPN
bjos-8668749	336	15	,	,	PUNCT
bjos-8668749	336	16	et	et	PROPN
bjos-8668749	336	17	al	al	PROPN
bjos-8668749	336	18	.	.	PROPN
bjos-8668749	336	19	attachment	attachment	NOUN
bjos-8668749	336	20	of	of	ADP
bjos-8668749	336	21	human	human	ADJ
bjos-8668749	336	22	bone	bone	NOUN
bjos-8668749	336	23	cells	cell	NOUN
bjos-8668749	336	24	to	to	ADP
bjos-8668749	336	25	tissue	tissue	NOUN
bjos-8668749	336	26	culture	culture	NOUN
bjos-8668749	336	27	polystyrene	polystyrene	NOUN
bjos-8668749	336	28	and	and	CCONJ
bjos-8668749	336	29	to	to	ADP
bjos-8668749	336	30	unmodified	unmodified	ADJ
bjos-8668749	336	31	polystyrene	polystyrene	NOUN
bjos-8668749	336	32	:	:	PUNCT
bjos-8668749	336	33	the	the	DET
bjos-8668749	336	34	effect	effect	NOUN
bjos-8668749	336	35	of	of	ADP
bjos-8668749	336	36	surface	surface	NOUN
bjos-8668749	336	37	chemistry	chemistry	NOUN
bjos-8668749	336	38	upon	upon	SCONJ
bjos-8668749	336	39	initial	initial	ADJ
bjos-8668749	336	40	cell	cell	NOUN
bjos-8668749	336	41	attachment	attachment	NOUN
bjos-8668749	336	42	.	.	PUNCT
bjos-8668749	337	1	j.	j.	PROPN
bjos-8668749	337	2	biomater	biomater	PROPN
bjos-8668749	337	3	.	.	PUNCT
bjos-8668749	338	1	sci	sci	PROPN
bjos-8668749	338	2	.	.	PUNCT
bjos-8668749	339	1	polym	polym	PROPN
bjos-8668749	339	2	ed	ed	NOUN
bjos-8668749	339	3	.	.	PUNCT
bjos-8668749	340	1	1993;5(3):245	1993;5(3):245	NUM
bjos-8668749	340	2	-	-	SYM
bjos-8668749	340	3	57	57	NUM
bjos-8668749	340	4	.	.	PUNCT
bjos-8668749	341	1	doi	doi	NOUN
bjos-8668749	341	2	:	:	PUNCT
bjos-8668749	341	3	10.1163/156856293x00339	10.1163/156856293x00339	NUM
bjos-8668749	341	4	.	.	NOUN
bjos-8668749	341	5	17	17	NUM
bjos-8668749	341	6	.	.	PUNCT
bjos-8668749	342	1	howlett	howlett	PROPN
bjos-8668749	342	2	cr	cr	PROPN
bjos-8668749	342	3	,	,	PUNCT
bjos-8668749	342	4	evans	evans	PROPN
bjos-8668749	342	5	md	md	PROPN
bjos-8668749	342	6	,	,	PUNCT
bjos-8668749	342	7	walsh	walsh	PROPN
bjos-8668749	342	8	wr	wr	PROPN
bjos-8668749	342	9	,	,	PUNCT
bjos-8668749	342	10	johnson	johnson	PROPN
bjos-8668749	342	11	g	g	PROPN
bjos-8668749	342	12	,	,	PUNCT
bjos-8668749	342	13	steele	steele	PROPN
bjos-8668749	342	14	jg	jg	PROPN
bjos-8668749	342	15	.	.	PUNCT
bjos-8668749	343	1	mechanism	mechanism	NOUN
bjos-8668749	343	2	of	of	ADP
bjos-8668749	343	3	initial	initial	ADJ
bjos-8668749	343	4	attachment	attachment	NOUN
bjos-8668749	343	5	of	of	ADP
bjos-8668749	343	6	cells	cell	NOUN
bjos-8668749	343	7	derived	derive	VERB
bjos-8668749	343	8	from	from	ADP
bjos-8668749	343	9	human	human	ADJ
bjos-8668749	343	10	bone	bone	NOUN
bjos-8668749	343	11	to	to	PART
bjos-8668749	343	12	commonly	commonly	ADV
bjos-8668749	343	13	used	use	VERB
bjos-8668749	343	14	prosthetic	prosthetic	ADJ
bjos-8668749	343	15	materials	material	NOUN
bjos-8668749	343	16	during	during	ADP
bjos-8668749	343	17	cell	cell	NOUN
bjos-8668749	343	18	culture	culture	NOUN
bjos-8668749	343	19	.	.	PUNCT
bjos-8668749	344	1	biomaterials	biomaterial	NOUN
bjos-8668749	344	2	.	.	PUNCT
bjos-8668749	345	1	1994	1994	NUM
bjos-8668749	345	2	feb;15(3):213	feb;15(3):213	PROPN
bjos-8668749	345	3	-	-	PUNCT
bjos-8668749	345	4	22	22	NUM
bjos-8668749	345	5	.	.	PUNCT
bjos-8668749	346	1	doi	doi	NOUN
bjos-8668749	346	2	:	:	PUNCT
bjos-8668749	346	3	10.1016/0142	10.1016/0142	NUM
bjos-8668749	346	4	-	-	SYM
bjos-8668749	346	5	9612(94)90070	9612(94)90070	NUM
bjos-8668749	346	6	-	-	SYM
bjos-8668749	346	7	1	1	NUM
bjos-8668749	346	8	.	.	NOUN
bjos-8668749	346	9	18	18	NUM
bjos-8668749	346	10	.	.	PUNCT
bjos-8668749	346	11	kilpadi	kilpadi	PROPN
bjos-8668749	346	12	kl	kl	PROPN
bjos-8668749	346	13	,	,	PUNCT
bjos-8668749	346	14	chang	chang	PROPN
bjos-8668749	346	15	pl	pl	PROPN
bjos-8668749	346	16	and	and	CCONJ
bjos-8668749	346	17	bellis	bellis	PROPN
bjos-8668749	346	18	sl	sl	VERB
bjos-8668749	346	19	.	.	PUNCT
bjos-8668749	346	20	hydroxylapatite	hydroxylapatite	PROPN
bjos-8668749	346	21	binds	bind	VERB
bjos-8668749	346	22	more	more	ADJ
bjos-8668749	346	23	serum	serum	NOUN
bjos-8668749	346	24	proteins	protein	NOUN
bjos-8668749	346	25	,	,	PUNCT
bjos-8668749	346	26	purified	purified	ADJ
bjos-8668749	346	27	integrins	integrin	NOUN
bjos-8668749	346	28	,	,	PUNCT
bjos-8668749	346	29	and	and	CCONJ
bjos-8668749	346	30	osteoblast	osteoblast	ADJ
bjos-8668749	346	31	precursor	precursor	NOUN
bjos-8668749	346	32	cells	cell	NOUN
bjos-8668749	346	33	than	than	ADP
bjos-8668749	346	34	titanium	titanium	NOUN
bjos-8668749	346	35	or	or	CCONJ
bjos-8668749	346	36	steel	steel	NOUN
bjos-8668749	346	37	.	.	PUNCT
bjos-8668749	347	1	j	j	PROPN
bjos-8668749	347	2	biomed	biome	VERB
bjos-8668749	347	3	mater	mater	NOUN
bjos-8668749	347	4	res	re	VERB
bjos-8668749	347	5	2001	2001	NUM
bjos-8668749	347	6	nov;57(2):258	nov;57(2):258	PROPN
bjos-8668749	347	7	-	-	PUNCT
bjos-8668749	347	8	67	67	PROPN
bjos-8668749	347	9	.	.	PUNCT
bjos-8668749	348	1	doi	doi	NOUN
bjos-8668749	348	2	:	:	PUNCT
bjos-8668749	348	3	10.1002/1097	10.1002/1097	NUM
bjos-8668749	348	4	-	-	PUNCT
bjos-8668749	348	5	4636(200111)57:2<258::aid	4636(200111)57:2<258::aid	NUM
bjos-8668749	348	6	-	-	PUNCT
bjos-8668749	348	7	jbm1166>3.0.co;2	jbm1166>3.0.co;2	PROPN
bjos-8668749	348	8	-	-	PUNCT
bjos-8668749	348	9	r.	r.	PROPN
bjos-8668749	348	10	19	19	NUM
bjos-8668749	348	11	.	.	PUNCT
bjos-8668749	349	1	gitirana	gitirana	PROPN
bjos-8668749	349	2	lb	lb	PROPN
bjos-8668749	349	3	.	.	PUNCT
bjos-8668749	350	1	[	[	X
bjos-8668749	350	2	tissue	tissue	NOUN
bjos-8668749	350	3	histology	histology	NOUN
bjos-8668749	350	4	]	]	PUNCT
bjos-8668749	350	5	.	.	PUNCT
bjos-8668749	351	1	rio	rio	PROPN
bjos-8668749	351	2	de	de	PROPN
bjos-8668749	351	3	janeiro	janeiro	PROPN
bjos-8668749	351	4	:	:	PUNCT
bjos-8668749	351	5	publit	publit	VERB
bjos-8668749	351	6	soluções	soluções	ADJ
bjos-8668749	351	7	editoriais	editoriais	NOUN
bjos-8668749	351	8	;	;	PUNCT
bjos-8668749	351	9	2013	2013	NUM
bjos-8668749	351	10	.	.	PUNCT
bjos-8668749	352	1	vol.1	vol.1	X
bjos-8668749	352	2	.	.	PUNCT
bjos-8668749	353	1	portuguese	portuguese	PROPN
bjos-8668749	353	2	.	.	PUNCT
bjos-8668749	354	1	20	20	NUM
bjos-8668749	354	2	.	.	PUNCT
bjos-8668749	354	3	kierszenbaum	kierszenbaum	PROPN
bjos-8668749	354	4	,	,	PUNCT
bjos-8668749	354	5	abraham	abraham	PROPN
bjos-8668749	354	6	l.	l.	PROPN
bjos-8668749	355	1	[	[	X
bjos-8668749	355	2	histology	histology	NOUN
bjos-8668749	355	3	and	and	CCONJ
bjos-8668749	355	4	cell	cell	NOUN
bjos-8668749	355	5	biology	biology	NOUN
bjos-8668749	355	6	:	:	PUNCT
bjos-8668749	355	7	an	an	DET
bjos-8668749	355	8	introduction	introduction	NOUN
bjos-8668749	355	9	to	to	ADP
bjos-8668749	355	10	pathology	pathology	NOUN
bjos-8668749	355	11	]	]	PUNCT
bjos-8668749	355	12	.	.	PUNCT
bjos-8668749	356	1	4	4	NUM
bjos-8668749	356	2	ed	ed	NOUN
bjos-8668749	356	3	.	.	PUNCT
bjos-8668749	357	1	rio	rio	PROPN
bjos-8668749	357	2	de	de	PROPN
bjos-8668749	357	3	janeiro	janeiro	PROPN
bjos-8668749	357	4	:	:	PUNCT
bjos-8668749	357	5	elsevier	elsevier	PROPN
bjos-8668749	357	6	science	science	PROPN
bjos-8668749	357	7	;	;	PUNCT
bjos-8668749	357	8	2016	2016	NUM
bjos-8668749	357	9	.	.	PUNCT
bjos-8668749	358	1	portuguese	portuguese	PROPN
bjos-8668749	358	2	.	.	PUNCT
bjos-8668749	359	1	21	21	NUM
bjos-8668749	359	2	.	.	X
bjos-8668749	360	1	goodsell	goodsell	PROPN
bjos-8668749	360	2	d.	d.	PROPN
bjos-8668749	360	3	molecule	molecule	NOUN
bjos-8668749	360	4	of	of	ADP
bjos-8668749	360	5	the	the	DET
bjos-8668749	360	6	mouth	mouth	NOUN
bjos-8668749	360	7	:	:	PUNCT
bjos-8668749	360	8	integrin	integrin	NOUN
bjos-8668749	360	9	.	.	PUNCT
bjos-8668749	361	1	protein	protein	NOUN
bjos-8668749	361	2	data	data	PROPN
bjos-8668749	361	3	bank	bank	NOUN
bjos-8668749	361	4	;	;	PUNCT
bjos-8668749	361	5	2011	2011	NUM
bjos-8668749	361	6	.	.	PUNCT
bjos-8668749	362	1	doi	doi	NOUN
bjos-8668749	362	2	:	:	PUNCT
bjos-8668749	362	3	10.2210	10.2210	NUM
bjos-8668749	362	4	/	/	SYM
bjos-8668749	362	5	rcsb_pdb	rcsb_pdb	PROPN
bjos-8668749	362	6	/	/	SYM
bjos-8668749	362	7	mom_2011_2	mom_2011_2	NOUN
bjos-8668749	362	8	.	.	PUNCT
bjos-8668749	363	1	22	22	NUM
bjos-8668749	363	2	.	.	PUNCT
bjos-8668749	364	1	arnaout	arnaout	PROPN
bjos-8668749	364	2	ma	ma	PROPN
bjos-8668749	364	3	,	,	PUNCT
bjos-8668749	364	4	goodman	goodman	PROPN
bjos-8668749	364	5	sl	sl	PROPN
bjos-8668749	364	6	,	,	PUNCT
bjos-8668749	364	7	xiong	xiong	PROPN
bjos-8668749	364	8	jp	jp	PROPN
bjos-8668749	364	9	.	.	PUNCT
bjos-8668749	365	1	structure	structure	NOUN
bjos-8668749	365	2	and	and	CCONJ
bjos-8668749	365	3	mechanics	mechanic	NOUN
bjos-8668749	365	4	of	of	ADP
bjos-8668749	365	5	integrin	integrin	NOUN
bjos-8668749	365	6	-	-	PUNCT
bjos-8668749	365	7	based	base	VERB
bjos-8668749	365	8	cell	cell	NOUN
bjos-8668749	365	9	adhesion	adhesion	NOUN
bjos-8668749	365	10	.	.	PUNCT
bjos-8668749	366	1	curr	curr	PROPN
bjos-8668749	366	2	opin	opin	NOUN
bjos-8668749	366	3	cell	cell	NOUN
bjos-8668749	366	4	biol	biol	NOUN
bjos-8668749	366	5	.	.	PUNCT
bjos-8668749	367	1	2007	2007	NUM
bjos-8668749	368	1	oct;19(5):495	oct;19(5):495	NUM
bjos-8668749	368	2	-	-	SYM
bjos-8668749	368	3	507	507	NUM
bjos-8668749	368	4	.	.	PUNCT
bjos-8668749	369	1	doi	doi	NOUN
bjos-8668749	369	2	:	:	PUNCT
bjos-8668749	369	3	10.1016	10.1016	NUM
bjos-8668749	369	4	/	/	SYM
bjos-8668749	369	5	j.ceb.2007.08.002	j.ceb.2007.08.002	NOUN
bjos-8668749	369	6	.	.	PUNCT
bjos-8668749	370	1	23	23	NUM
bjos-8668749	370	2	.	.	PUNCT
bjos-8668749	370	3	shattil	shattil	PROPN
bjos-8668749	370	4	sj	sj	PROPN
bjos-8668749	370	5	,	,	PUNCT
bjos-8668749	370	6	kim	kim	PROPN
bjos-8668749	370	7	c	c	PROPN
bjos-8668749	370	8	,	,	PUNCT
bjos-8668749	370	9	ginsberg	ginsberg	PROPN
bjos-8668749	370	10	mh	mh	PROPN
bjos-8668749	370	11	.	.	PUNCT
bjos-8668749	371	1	the	the	DET
bjos-8668749	371	2	final	final	ADJ
bjos-8668749	371	3	steps	step	NOUN
bjos-8668749	371	4	of	of	ADP
bjos-8668749	371	5	integrin	integrin	NOUN
bjos-8668749	371	6	activation	activation	NOUN
bjos-8668749	371	7	:	:	PUNCT
bjos-8668749	371	8	the	the	DET
bjos-8668749	371	9	end	end	NOUN
bjos-8668749	371	10	game	game	NOUN
bjos-8668749	371	11	.	.	PUNCT
bjos-8668749	372	1	nat	nat	PROPN
bjos-8668749	372	2	rev	rev	PROPN
bjos-8668749	372	3	cell	cell	NOUN
bjos-8668749	372	4	mol	mol	ADP
bjos-8668749	372	5	cell	cell	NOUN
bjos-8668749	372	6	biol	biol	NOUN
bjos-8668749	372	7	.	.	PUNCT
bjos-8668749	373	1	2010	2010	NUM
bjos-8668749	373	2	apr;11(4):288	apr;11(4):288	NUM
bjos-8668749	373	3	-	-	SYM
bjos-8668749	373	4	300	300	NUM
bjos-8668749	373	5	.	.	PUNCT
bjos-8668749	374	1	doi	doi	NOUN
bjos-8668749	374	2	:	:	PUNCT
bjos-8668749	374	3	10.1038	10.1038	NUM
bjos-8668749	374	4	/	/	SYM
bjos-8668749	374	5	nrm2871	nrm2871	NOUN
bjos-8668749	374	6	.	.	PUNCT
bjos-8668749	375	1	24	24	NUM
bjos-8668749	375	2	.	.	PUNCT
bjos-8668749	375	3	luo	luo	PROPN
bjos-8668749	375	4	bh	bh	PROPN
bjos-8668749	375	5	,	,	PUNCT
bjos-8668749	375	6	carman	carman	PROPN
bjos-8668749	375	7	cv	cv	PROPN
bjos-8668749	375	8	,	,	PUNCT
bjos-8668749	375	9	springer	springer	NOUN
bjos-8668749	375	10	ta	ta	PROPN
bjos-8668749	375	11	.	.	PUNCT
bjos-8668749	375	12	structural	structural	ADJ
bjos-8668749	375	13	basis	basis	NOUN
bjos-8668749	375	14	of	of	ADP
bjos-8668749	375	15	integrin	integrin	NOUN
bjos-8668749	375	16	regulation	regulation	NOUN
bjos-8668749	375	17	and	and	CCONJ
bjos-8668749	375	18	signaling	signal	VERB
bjos-8668749	375	19	.	.	PUNCT
bjos-8668749	376	1	annu	annu	PROPN
bjos-8668749	376	2	rev	rev	VERB
bjos-8668749	376	3	immunol	immunol	NOUN
bjos-8668749	376	4	.	.	PUNCT
bjos-8668749	377	1	2007;25:619	2007;25:619	X
bjos-8668749	377	2	-	-	SYM
bjos-8668749	377	3	47	47	NUM
bjos-8668749	377	4	.	.	PUNCT
bjos-8668749	378	1	doi	doi	NOUN
bjos-8668749	378	2	:	:	PUNCT
bjos-8668749	378	3	10.1146	10.1146	NUM
bjos-8668749	378	4	/	/	SYM
bjos-8668749	378	5	annurev.immunol.25.022106.141618	annurev.immunol.25.022106.141618	PROPN
bjos-8668749	378	6	.	.	PUNCT
bjos-8668749	379	1	25	25	NUM
bjos-8668749	379	2	.	.	PUNCT
bjos-8668749	380	1	kay	kay	PROPN
bjos-8668749	380	2	c	c	PROPN
bjos-8668749	380	3	dee	dee	PROPN
bjos-8668749	380	4	,	,	PUNCT
bjos-8668749	380	5	david	david	PROPN
bjos-8668749	380	6	a	a	DET
bjos-8668749	380	7	puleo	puleo	NOUN
bjos-8668749	380	8	,	,	PUNCT
bjos-8668749	380	9	rena	rena	PROPN
bjos-8668749	380	10	bizios	bizios	PROPN
bjos-8668749	380	11	.	.	PUNCT
bjos-8668749	381	1	an	an	DET
bjos-8668749	381	2	introduction	introduction	NOUN
bjos-8668749	381	3	to	to	ADP
bjos-8668749	381	4	tissue	tissue	NOUN
bjos-8668749	381	5	biomaterials	biomaterial	NOUN
bjos-8668749	381	6	interactions	interaction	NOUN
bjos-8668749	381	7	.	.	PUNCT
bjos-8668749	382	1	wiley	wiley	PROPN
bjos-8668749	382	2	-	-	PUNCT
bjos-8668749	382	3	liss	liss	PROPN
bjos-8668749	382	4	publication	publication	NOUN
bjos-8668749	382	5	;	;	PUNCT
bjos-8668749	382	6	2002	2002	NUM
bjos-8668749	382	7	.	.	PUNCT
bjos-8668749	383	1	26	26	NUM
bjos-8668749	383	2	.	.	PUNCT
bjos-8668749	384	1	li	li	PROPN
bjos-8668749	384	2	f	f	PROPN
bjos-8668749	384	3	,	,	PUNCT
bjos-8668749	384	4	carlsson	carlsson	PROPN
bjos-8668749	384	5	d	d	PROPN
bjos-8668749	384	6	,	,	PUNCT
bjos-8668749	384	7	lohmann	lohmann	PROPN
bjos-8668749	384	8	c	c	NOUN
bjos-8668749	384	9	,	,	PUNCT
bjos-8668749	384	10	suuronen	suuronen	PROPN
bjos-8668749	384	11	e	e	NOUN
bjos-8668749	384	12	,	,	PUNCT
bjos-8668749	384	13	vascotto	vascotto	NOUN
bjos-8668749	384	14	s	s	PROPN
bjos-8668749	384	15	,	,	PUNCT
bjos-8668749	384	16	kobuch	kobuch	ADJ
bjos-8668749	384	17	k	k	PROPN
bjos-8668749	384	18	,	,	PUNCT
bjos-8668749	384	19	et	et	PROPN
bjos-8668749	384	20	al	al	PROPN
bjos-8668749	384	21	.	.	PUNCT
bjos-8668749	384	22	cellular	cellular	ADJ
bjos-8668749	384	23	and	and	CCONJ
bjos-8668749	384	24	nerve	nerve	NOUN
bjos-8668749	384	25	regeneration	regeneration	NOUN
bjos-8668749	384	26	within	within	ADP
bjos-8668749	384	27	a	a	DET
bjos-8668749	384	28	biosynthetic	biosynthetic	ADJ
bjos-8668749	384	29	extracellular	extracellular	ADJ
bjos-8668749	384	30	matrix	matrix	NOUN
bjos-8668749	384	31	for	for	ADP
bjos-8668749	384	32	corneal	corneal	ADJ
bjos-8668749	384	33	transplantation	transplantation	NOUN
bjos-8668749	384	34	.	.	PUNCT
bjos-8668749	385	1	proc	proc	PROPN
bjos-8668749	385	2	natl	natl	PROPN
bjos-8668749	385	3	acad	acad	PROPN
bjos-8668749	385	4	sci	sci	PROPN
bjos-8668749	385	5	usa	usa	PROPN
bjos-8668749	385	6	.	.	PROPN
bjos-8668749	385	7	2003	2003	NUM
bjos-8668749	385	8	dec;100(26):15346	dec;100(26):15346	PROPN
bjos-8668749	385	9	-	-	PUNCT
bjos-8668749	385	10	51	51	NUM
bjos-8668749	385	11	.	.	PUNCT
bjos-8668749	386	1	doi	doi	NOUN
bjos-8668749	386	2	:	:	PUNCT
bjos-8668749	386	3	10.1073	10.1073	NUM
bjos-8668749	386	4	/	/	SYM
bjos-8668749	386	5	pnas.2536767100	pnas.2536767100	PROPN
bjos-8668749	386	6	.	.	PROPN
bjos-8668749	386	7	27	27	NUM
bjos-8668749	386	8	.	.	PUNCT
bjos-8668749	387	1	elmengaard	elmengaard	PROPN
bjos-8668749	387	2	b	b	PROPN
bjos-8668749	387	3	,	,	PUNCT
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bjos-8668749	387	5	je	je	PROPN
bjos-8668749	387	6	,	,	PUNCT
bjos-8668749	387	7	soballe	soballe	PROPN
bjos-8668749	387	8	k.	k.	PROPN
bjos-8668749	387	9	in	in	ADP
bjos-8668749	387	10	vivo	vivo	ADJ
bjos-8668749	387	11	study	study	NOUN
bjos-8668749	387	12	of	of	ADP
bjos-8668749	387	13	the	the	DET
bjos-8668749	387	14	effect	effect	NOUN
bjos-8668749	387	15	of	of	ADP
bjos-8668749	387	16	rgd	rgd	PROPN
bjos-8668749	387	17	treatment	treatment	NOUN
bjos-8668749	387	18	on	on	ADP
bjos-8668749	387	19	bone	bone	NOUN
bjos-8668749	387	20	ongrowth	ongrowth	NOUN
bjos-8668749	387	21	on	on	ADP
bjos-8668749	387	22	press	press	NOUN
bjos-8668749	387	23	-	-	PUNCT
bjos-8668749	387	24	fit	fit	NOUN
bjos-8668749	387	25	titanium	titanium	NOUN
bjos-8668749	387	26	alloy	alloy	NOUN
bjos-8668749	387	27	implants	implant	NOUN
bjos-8668749	387	28	biomaterials	biomaterial	NOUN
bjos-8668749	387	29	.	.	PUNCT
bjos-8668749	388	1	2005	2005	NUM
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bjos-8668749	388	3	-	-	PUNCT
bjos-8668749	388	4	6	6	NUM
bjos-8668749	388	5	.	.	PUNCT
bjos-8668749	389	1	doi	doi	NOUN
bjos-8668749	389	2	:	:	PUNCT
bjos-8668749	389	3	10.1016	10.1016	NUM
bjos-8668749	389	4	/	/	SYM
bjos-8668749	389	5	j.biomaterials.2004.09.039	j.biomaterials.2004.09.039	PROPN
bjos-8668749	389	6	.	.	PUNCT
bjos-8668749	390	1	15	15	NUM
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bjos-8668749	390	5	.	.	PROPN
bjos-8668749	391	1	braz	braz	PROPN
bjos-8668749	391	2	j	j	PROPN
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bjos-8668749	391	5	.	.	PUNCT
bjos-8668749	392	1	2023;22	2023;22	NUM
bjos-8668749	392	2	:	:	PUNCT
bjos-8668749	392	3	e238749	e238749	PROPN
bjos-8668749	392	4	28	28	NUM
bjos-8668749	392	5	.	.	PUNCT
bjos-8668749	393	1	cowles	cowles	PROPN
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bjos-8668749	393	3	,	,	PUNCT
bjos-8668749	393	4	brailey	brailey	PROPN
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bjos-8668749	393	6	,	,	PUNCT
bjos-8668749	393	7	gronowicz	gronowicz	PROPN
bjos-8668749	393	8	ga	ga	PROPN
bjos-8668749	393	9	.	.	PROPN
bjos-8668749	393	10	integrin	integrin	NOUN
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bjos-8668749	393	18	and	and	CCONJ
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bjos-8668749	393	20	in	in	ADP
bjos-8668749	393	21	osteoblasts	osteoblast	NOUN
bjos-8668749	393	22	.	.	PUNCT
bjos-8668749	394	1	j	j	PROPN
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bjos-8668749	394	5	.	.	PROPN
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bjos-8668749	394	9	-	-	SYM
bjos-8668749	394	10	37	37	NUM
bjos-8668749	394	11	.	.	PUNCT
bjos-8668749	395	1	doi	doi	NOUN
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bjos-8668749	395	3	10.1002/1097	10.1002/1097	NUM
bjos-8668749	395	4	-	-	SYM
bjos-8668749	395	5	4636(20001215)52:4<725::aid	4636(20001215)52:4<725::aid	NUM
bjos-8668749	395	6	-	-	PUNCT
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bjos-8668749	395	8	-	-	PUNCT
bjos-8668749	395	9	o.	o.	NOUN
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bjos-8668749	395	11	.	.	PUNCT
bjos-8668749	396	1	chang	chang	PROPN
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bjos-8668749	396	3	,	,	PUNCT
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bjos-8668749	396	6	,	,	PUNCT
bjos-8668749	396	7	feng	feng	PROPN
bjos-8668749	396	8	sw	sw	PROPN
bjos-8668749	396	9	,	,	PUNCT
bjos-8668749	396	10	huang	huang	PROPN
bjos-8668749	396	11	hm	hm	PROPN
bjos-8668749	396	12	,	,	PUNCT
bjos-8668749	396	13	chang	chang	PROPN
bjos-8668749	396	14	ch	ch	PROPN
bjos-8668749	396	15	,	,	PUNCT
bjos-8668749	396	16	lin	lin	PROPN
bjos-8668749	396	17	ct	ct	PROPN
bjos-8668749	396	18	,	,	PUNCT
bjos-8668749	396	19	et	et	PROPN
bjos-8668749	396	20	al	al	PROPN
bjos-8668749	396	21	.	.	PROPN
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bjos-8668749	396	23	-	-	PUNCT
bjos-8668749	396	24	grafted	graft	VERB
bjos-8668749	396	25	titanium	titanium	NOUN
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bjos-8668749	396	27	implants	implant	NOUN
bjos-8668749	396	28	:	:	PUNCT
bjos-8668749	396	29	an	an	DET
bjos-8668749	396	30	in	in	ADP
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bjos-8668749	396	33	.	.	PUNCT
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bjos-8668749	396	35	res	re	NOUN
bjos-8668749	396	36	int	int	NOUN
bjos-8668749	396	37	.	.	PUNCT
bjos-8668749	397	1	2016;2016:2414809	2016;2016:2414809	NUM
bjos-8668749	397	2	.	.	PUNCT
bjos-8668749	398	1	doi	doi	NOUN
bjos-8668749	398	2	:	:	PUNCT
bjos-8668749	398	3	10.1155/2016/2414809	10.1155/2016/2414809	NUM
bjos-8668749	398	4	.	.	NOUN
bjos-8668749	399	1	30	30	NUM
bjos-8668749	399	2	.	.	PUNCT
bjos-8668749	400	1	parisi	parisi	PROPN
bjos-8668749	400	2	l	l	PROPN
bjos-8668749	400	3	,	,	PUNCT
bjos-8668749	400	4	ghezzi	ghezzi	NOUN
bjos-8668749	400	5	b	b	PROPN
bjos-8668749	400	6	,	,	PUNCT
bjos-8668749	400	7	bianchi	bianchi	NOUN
bjos-8668749	400	8	mg	mg	PROPN
bjos-8668749	400	9	,	,	PUNCT
bjos-8668749	400	10	toffoli	toffoli	PROPN
bjos-8668749	400	11	a	a	PRON
bjos-8668749	400	12	,	,	PUNCT
bjos-8668749	400	13	rossi	rossi	ADJ
bjos-8668749	400	14	f	f	X
bjos-8668749	400	15	,	,	PUNCT
bjos-8668749	400	16	bussolati	bussolati	PROPN
bjos-8668749	400	17	o	o	PROPN
bjos-8668749	400	18	,	,	PUNCT
bjos-8668749	400	19	et	et	PROPN
bjos-8668749	400	20	al	al	PROPN
bjos-8668749	400	21	.	.	PUNCT
bjos-8668749	400	22	titanium	titanium	NOUN
bjos-8668749	400	23	dental	dental	ADJ
bjos-8668749	400	24	implants	implant	NOUN
bjos-8668749	400	25	hydrophilicity	hydrophilicity	NOUN
bjos-8668749	400	26	promotes	promote	VERB
bjos-8668749	400	27	preferential	preferential	ADJ
bjos-8668749	400	28	serum	serum	NOUN
bjos-8668749	400	29	fibronectin	fibronectin	NOUN
bjos-8668749	400	30	over	over	ADP
bjos-8668749	400	31	albumin	albumin	ADJ
bjos-8668749	400	32	competitive	competitive	ADJ
bjos-8668749	400	33	adsorption	adsorption	NOUN
bjos-8668749	400	34	modulating	modulate	VERB
bjos-8668749	400	35	early	early	ADJ
bjos-8668749	400	36	cell	cell	NOUN
bjos-8668749	400	37	response	response	NOUN
bjos-8668749	400	38	.	.	PUNCT
bjos-8668749	401	1	mater	mater	NOUN
bjos-8668749	401	2	sci	sci	PROPN
bjos-8668749	401	3	eng	eng	PROPN
bjos-8668749	401	4	c	c	PROPN
bjos-8668749	401	5	mater	mater	NOUN
bjos-8668749	401	6	biol	biol	PROPN
bjos-8668749	401	7	appl	appl	PROPN
bjos-8668749	401	8	.	.	PUNCT
bjos-8668749	402	1	2020	2020	NUM
bjos-8668749	403	1	dec;117:111307	dec;117:111307	PROPN
bjos-8668749	403	2	.	.	PUNCT
bjos-8668749	403	3	doi	doi	PROPN
bjos-8668749	403	4	:	:	PUNCT
bjos-8668749	403	5	10.1016	10.1016	NUM
bjos-8668749	403	6	/	/	SYM
bjos-8668749	403	7	j.msec.2020.111307	j.msec.2020.111307	PROPN
bjos-8668749	403	8	.	.	PUNCT
bjos-8668749	404	1	31	31	NUM
bjos-8668749	404	2	.	.	PUNCT
bjos-8668749	405	1	elkarargy	elkarargy	NOUN
bjos-8668749	405	2	a.	a.	NOUN
bjos-8668749	405	3	biological	biological	ADJ
bjos-8668749	405	4	functionalization	functionalization	NOUN
bjos-8668749	405	5	of	of	ADP
bjos-8668749	405	6	dental	dental	ADJ
bjos-8668749	405	7	implants	implant	NOUN
bjos-8668749	405	8	with	with	ADP
bjos-8668749	405	9	fibronectin	fibronectin	NOUN
bjos-8668749	405	10	:	:	PUNCT
bjos-8668749	405	11	a	a	DET
bjos-8668749	405	12	scanning	scan	VERB
bjos-8668749	405	13	electron	electron	NOUN
bjos-8668749	405	14	microscopic	microscopic	ADJ
bjos-8668749	405	15	study	study	NOUN
bjos-8668749	405	16	.	.	PUNCT
bjos-8668749	406	1	int	int	PROPN
bjos-8668749	406	2	j	j	PROPN
bjos-8668749	406	3	health	health	PROPN
bjos-8668749	406	4	sci	sci	PROPN
bjos-8668749	406	5	(	(	PUNCT
bjos-8668749	406	6	qassim	qassim	NOUN
bjos-8668749	406	7	)	)	PUNCT
bjos-8668749	406	8	.	.	PUNCT
bjos-8668749	407	1	2014	2014	NUM
bjos-8668749	407	2	jan;8(1):57	jan;8(1):57	NOUN
bjos-8668749	407	3	-	-	PUNCT
bjos-8668749	407	4	66	66	NUM
bjos-8668749	407	5	.	.	PUNCT
bjos-8668749	408	1	doi	doi	NOUN
bjos-8668749	408	2	:	:	PUNCT
bjos-8668749	408	3	10.12816/0006072	10.12816/0006072	NUM
bjos-8668749	408	4	.	.	NOUN
bjos-8668749	408	5	32	32	NUM
bjos-8668749	408	6	.	.	PUNCT
bjos-8668749	409	1	ren	ren	NOUN
bjos-8668749	409	2	x	x	SYM
bjos-8668749	409	3	,	,	PUNCT
bjos-8668749	409	4	wu	wu	PROPN
bjos-8668749	409	5	y	y	PROPN
bjos-8668749	409	6	,	,	PUNCT
bjos-8668749	409	7	cheng	cheng	PROPN
bjos-8668749	409	8	y	y	PROPN
bjos-8668749	409	9	,	,	PUNCT
bjos-8668749	409	10	ma	ma	PROPN
bjos-8668749	409	11	h	h	PROPN
bjos-8668749	409	12	,	,	PUNCT
bjos-8668749	409	13	wei	wei	PROPN
bjos-8668749	409	14	s.	s.	PROPN
bjos-8668749	409	15	fibronectin	fibronectin	NOUN
bjos-8668749	409	16	and	and	CCONJ
bjos-8668749	409	17	bone	bone	NOUN
bjos-8668749	409	18	morphogenetic	morphogenetic	ADJ
bjos-8668749	409	19	protein-2	protein-2	NOUN
bjos-8668749	409	20	-	-	PUNCT
bjos-8668749	409	21	decorated	decorate	VERB
bjos-8668749	409	22	poly(oegma	poly(oegma	PROPN
bjos-8668749	409	23	-	-	PUNCT
bjos-8668749	409	24	r	r	NOUN
bjos-8668749	409	25	-	-	PUNCT
bjos-8668749	409	26	hema	hema	NOUN
bjos-8668749	409	27	)	)	PUNCT
bjos-8668749	409	28	brushes	brush	NOUN
bjos-8668749	409	29	promote	promote	VERB
bjos-8668749	409	30	osseointegration	osseointegration	NOUN
bjos-8668749	409	31	of	of	ADP
bjos-8668749	409	32	titanium	titanium	NOUN
bjos-8668749	409	33	surfaces	surface	NOUN
bjos-8668749	409	34	.	.	PUNCT
bjos-8668749	410	1	langmuir	langmuir	PROPN
bjos-8668749	410	2	.	.	PUNCT
bjos-8668749	411	1	2011	2011	NUM
bjos-8668749	411	2	oct	oct	PROPN
bjos-8668749	411	3	4;27(19):12069	4;27(19):12069	NUM
bjos-8668749	411	4	-	-	SYM
bjos-8668749	411	5	73	73	NUM
bjos-8668749	411	6	.	.	PUNCT
bjos-8668749	412	1	doi	doi	NOUN
bjos-8668749	412	2	:	:	PUNCT
bjos-8668749	412	3	10.1021	10.1021	NUM
bjos-8668749	412	4	/	/	SYM
bjos-8668749	412	5	la202438u	la202438u	PROPN
bjos-8668749	412	6	.	.	PUNCT
bjos-8668749	413	1	33	33	NUM
bjos-8668749	413	2	.	.	PUNCT
bjos-8668749	414	1	takahashi	takahashi	PROPN
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bjos-8668749	414	3	,	,	PUNCT
bjos-8668749	414	4	takahashi	takahashi	PROPN
bjos-8668749	414	5	s	s	PROPN
bjos-8668749	414	6	,	,	PUNCT
bjos-8668749	414	7	tsujino	tsujino	PROPN
bjos-8668749	414	8	t	t	PROPN
bjos-8668749	414	9	,	,	PUNCT
bjos-8668749	414	10	isobe	isobe	PROPN
bjos-8668749	414	11	k	k	PROPN
bjos-8668749	414	12	,	,	PUNCT
bjos-8668749	414	13	watanabe	watanabe	PROPN
bjos-8668749	414	14	t	t	PROPN
bjos-8668749	414	15	,	,	PUNCT
bjos-8668749	414	16	kitamura	kitamura	PROPN
bjos-8668749	414	17	y	y	PROPN
bjos-8668749	414	18	,	,	PUNCT
bjos-8668749	414	19	et	et	PROPN
bjos-8668749	414	20	al	al	PROPN
bjos-8668749	414	21	.	.	PUNCT
bjos-8668749	415	1	platelet	platelet	NOUN
bjos-8668749	415	2	adhesion	adhesion	NOUN
bjos-8668749	415	3	on	on	ADP
bjos-8668749	415	4	commercially	commercially	ADV
bjos-8668749	415	5	pure	pure	ADJ
bjos-8668749	415	6	titanium	titanium	NOUN
bjos-8668749	415	7	plates	plate	NOUN
bjos-8668749	415	8	in	in	ADP
bjos-8668749	415	9	vitro	vitro	X
bjos-8668749	416	1	i	i	PRON
bjos-8668749	416	2	:	:	PUNCT
bjos-8668749	416	3	effects	effect	NOUN
bjos-8668749	416	4	of	of	ADP
bjos-8668749	416	5	plasma	plasma	NOUN
bjos-8668749	416	6	components	component	NOUN
bjos-8668749	416	7	and	and	CCONJ
bjos-8668749	416	8	involvement	involvement	NOUN
bjos-8668749	416	9	of	of	ADP
bjos-8668749	416	10	the	the	DET
bjos-8668749	416	11	von	von	PROPN
bjos-8668749	416	12	willebrand	willebrand	NOUN
bjos-8668749	416	13	factor	factor	NOUN
bjos-8668749	416	14	and	and	CCONJ
bjos-8668749	416	15	fibronectin	fibronectin	NOUN
bjos-8668749	416	16	.	.	PUNCT
bjos-8668749	417	1	int	int	NOUN
bjos-8668749	417	2	j	j	PROPN
bjos-8668749	417	3	implant	implant	PROPN
bjos-8668749	417	4	dent	dent	NOUN
bjos-8668749	417	5	.	.	PUNCT
bjos-8668749	418	1	2019	2019	NUM
bjos-8668749	418	2	feb;5(1):5	feb;5(1):5	NOUN
bjos-8668749	418	3	.	.	PUNCT
bjos-8668749	418	4	doi	doi	NOUN
bjos-8668749	418	5	:	:	PUNCT
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bjos-8668749	418	7	/	/	SYM
bjos-8668749	418	8	s40729	s40729	VERB
bjos-8668749	418	9	-	-	PUNCT
bjos-8668749	418	10	019	019	NUM
bjos-8668749	418	11	-	-	PUNCT
bjos-8668749	418	12	0160	0160	NUM
bjos-8668749	418	13	-	-	PUNCT
bjos-8668749	418	14	z.	z.	PROPN
bjos-8668749	418	15	34	34	NUM
bjos-8668749	418	16	.	.	PUNCT
bjos-8668749	418	17	grill	grill	PROPN
bjos-8668749	418	18	v	v	PROPN
bjos-8668749	418	19	,	,	PUNCT
bjos-8668749	418	20	sandrucci	sandrucci	PROPN
bjos-8668749	418	21	ma	ma	PROPN
bjos-8668749	418	22	,	,	PUNCT
bjos-8668749	418	23	rizzo	rizzo	PROPN
bjos-8668749	418	24	r	r	PROPN
bjos-8668749	418	25	,	,	PUNCT
bjos-8668749	418	26	narducci	narducci	NOUN
bjos-8668749	418	27	p	p	NOUN
bjos-8668749	418	28	,	,	PUNCT
bjos-8668749	418	29	bareggi	bareggi	ADJ
bjos-8668749	418	30	r	r	NOUN
bjos-8668749	418	31	,	,	PUNCT
bjos-8668749	418	32	dorigo	dorigo	PROPN
bjos-8668749	418	33	e.	e.	PROPN
bjos-8668749	418	34	biocompatibility	biocompatibility	PROPN
bjos-8668749	418	35	in	in	ADP
bjos-8668749	418	36	vitro	vitro	X
bjos-8668749	418	37	of	of	ADP
bjos-8668749	418	38	titanium	titanium	NOUN
bjos-8668749	418	39	dental	dental	ADJ
bjos-8668749	418	40	implants	implant	NOUN
bjos-8668749	418	41	.	.	PUNCT
bjos-8668749	419	1	immunocytochemical	immunocytochemical	ADJ
bjos-8668749	419	2	expression	expression	NOUN
bjos-8668749	419	3	of	of	ADP
bjos-8668749	419	4	fibronectin	fibronectin	NOUN
bjos-8668749	419	5	and	and	CCONJ
bjos-8668749	419	6	extracellular	extracellular	ADJ
bjos-8668749	419	7	matrix	matrix	NOUN
bjos-8668749	419	8	receptors	receptor	NOUN
bjos-8668749	419	9	.	.	PUNCT
bjos-8668749	420	1	minerva	minerva	PROPN
bjos-8668749	420	2	stomatol	stomatol	PROPN
bjos-8668749	420	3	.	.	PROPN
bjos-8668749	421	1	2000	2000	NUM
bjos-8668749	421	2	mar;49(3):77	mar;49(3):77	PROPN
bjos-8668749	421	3	-	-	PUNCT
bjos-8668749	421	4	85	85	NUM
bjos-8668749	421	5	.	.	NOUN
bjos-8668749	421	6	35	35	NUM
bjos-8668749	421	7	.	.	PUNCT
bjos-8668749	422	1	grunkemeier	grunkemei	ADJ
bjos-8668749	422	2	jm	jm	PROPN
bjos-8668749	422	3	,	,	PUNCT
bjos-8668749	422	4	tsai	tsai	PROPN
bjos-8668749	422	5	wb	wb	PROPN
bjos-8668749	422	6	,	,	PUNCT
bjos-8668749	422	7	mcfarland	mcfarland	PROPN
bjos-8668749	422	8	cd	cd	PROPN
bjos-8668749	422	9	,	,	PUNCT
bjos-8668749	422	10	horbett	horbett	PROPN
bjos-8668749	422	11	ta	ta	PROPN
bjos-8668749	422	12	.	.	PUNCT
bjos-8668749	423	1	the	the	DET
bjos-8668749	423	2	effect	effect	NOUN
bjos-8668749	423	3	of	of	ADP
bjos-8668749	423	4	adsorbed	adsorb	VERB
bjos-8668749	423	5	fibrinogen	fibrinogen	NOUN
bjos-8668749	423	6	,	,	PUNCT
bjos-8668749	423	7	fibronectin	fibronectin	NOUN
bjos-8668749	423	8	,	,	PUNCT
bjos-8668749	423	9	von	von	PROPN
bjos-8668749	423	10	willebrand	willebrand	NOUN
bjos-8668749	423	11	factor	factor	NOUN
bjos-8668749	423	12	and	and	CCONJ
bjos-8668749	423	13	vitronectin	vitronectin	NOUN
bjos-8668749	423	14	on	on	ADP
bjos-8668749	423	15	the	the	DET
bjos-8668749	423	16	procoagulant	procoagulant	NOUN
bjos-8668749	423	17	state	state	NOUN
bjos-8668749	423	18	of	of	ADP
bjos-8668749	423	19	adherent	adherent	ADJ
bjos-8668749	423	20	platelets	platelet	NOUN
bjos-8668749	423	21	.	.	PUNCT
bjos-8668749	424	1	biomaterials	biomaterial	NOUN
bjos-8668749	424	2	.	.	PUNCT
bjos-8668749	425	1	2000	2000	NUM
bjos-8668749	425	2	nov;21(22):2243	nov;21(22):2243	NOUN
bjos-8668749	425	3	-	-	PUNCT
bjos-8668749	425	4	52	52	NUM
bjos-8668749	425	5	.	.	PUNCT
bjos-8668749	426	1	doi	doi	NOUN
bjos-8668749	426	2	:	:	PUNCT
bjos-8668749	426	3	10.1016	10.1016	NUM
bjos-8668749	426	4	/	/	SYM
bjos-8668749	426	5	s0142	s0142	PRON
bjos-8668749	426	6	-	-	PUNCT
bjos-8668749	426	7	9612(00)00150	9612(00)00150	NUM
bjos-8668749	426	8	-	-	PUNCT
bjos-8668749	426	9	2	2	NUM
bjos-8668749	426	10	.	.	NUM
bjos-8668749	426	11	36	36	NUM
bjos-8668749	426	12	.	.	PUNCT
bjos-8668749	427	1	grill	grill	NOUN
bjos-8668749	427	2	v	v	PROPN
bjos-8668749	427	3	,	,	PUNCT
bjos-8668749	427	4	sandrucci	sandrucci	PROPN
bjos-8668749	427	5	ma	ma	PROPN
bjos-8668749	427	6	,	,	PUNCT
bjos-8668749	427	7	basa	basa	PROPN
bjos-8668749	427	8	m	m	PROPN
bjos-8668749	427	9	,	,	PUNCT
bjos-8668749	427	10	di	di	PROPN
bjos-8668749	427	11	lenarda	lenarda	PROPN
bjos-8668749	427	12	r	r	PROPN
bjos-8668749	427	13	,	,	PUNCT
bjos-8668749	427	14	dorigo	dorigo	PROPN
bjos-8668749	427	15	e	e	PROPN
bjos-8668749	427	16	,	,	PUNCT
bjos-8668749	427	17	martelli	martelli	PROPN
bjos-8668749	427	18	am	be	AUX
bjos-8668749	427	19	,	,	PUNCT
bjos-8668749	427	20	bareggi	bareggi	ADJ
bjos-8668749	427	21	r	r	NOUN
bjos-8668749	427	22	,	,	PUNCT
bjos-8668749	427	23	narducci	narducci	NOUN
bjos-8668749	428	1	p.	p.	NOUN
bjos-8668749	428	2	the	the	DET
bjos-8668749	428	3	presence	presence	NOUN
bjos-8668749	428	4	of	of	ADP
bjos-8668749	428	5	implant	implant	ADJ
bjos-8668749	428	6	materials	material	NOUN
bjos-8668749	428	7	influences	influence	VERB
bjos-8668749	428	8	fibronectin	fibronectin	NOUN
bjos-8668749	428	9	arrangement	arrangement	NOUN
bjos-8668749	428	10	and	and	CCONJ
bjos-8668749	428	11	cell	cell	NOUN
bjos-8668749	428	12	growth	growth	NOUN
bjos-8668749	428	13	in	in	ADP
bjos-8668749	428	14	fibroblast	fibroblast	ADJ
bjos-8668749	428	15	cultures	culture	NOUN
bjos-8668749	428	16	.	.	PUNCT
bjos-8668749	429	1	boll	boll	PROPN
bjos-8668749	429	2	soc	soc	PROPN
bjos-8668749	429	3	ital	ital	PROPN
bjos-8668749	429	4	biol	biol	PROPN
bjos-8668749	429	5	sper	sper	NOUN
bjos-8668749	429	6	.	.	PUNCT
bjos-8668749	430	1	1996	1996	NUM
bjos-8668749	430	2	mar	mar	PROPN
bjos-8668749	430	3	-	-	PUNCT
bjos-8668749	430	4	apr;72(3	apr;72(3	NOUN
bjos-8668749	430	5	-	-	PUNCT
bjos-8668749	430	6	4):87	4):87	NUM
bjos-8668749	430	7	-	-	PUNCT
bjos-8668749	430	8	94	94	NUM
bjos-8668749	430	9	.	.	PUNCT
bjos-8668749	431	1	37	37	NUM
bjos-8668749	431	2	.	.	PUNCT
bjos-8668749	432	1	lüthen	lüthen	ADV
bjos-8668749	432	2	f	f	X
bjos-8668749	432	3	,	,	PUNCT
bjos-8668749	432	4	lange	lange	NOUN
bjos-8668749	432	5	r	r	NOUN
bjos-8668749	432	6	,	,	PUNCT
bjos-8668749	432	7	becker	becker	NOUN
bjos-8668749	432	8	p	p	X
bjos-8668749	432	9	,	,	PUNCT
bjos-8668749	432	10	rychly	rychly	ADV
bjos-8668749	432	11	j	j	PROPN
bjos-8668749	432	12	,	,	PUNCT
bjos-8668749	432	13	beck	beck	PROPN
bjos-8668749	432	14	u	u	PROPN
bjos-8668749	432	15	,	,	PUNCT
bjos-8668749	432	16	nebe	nebe	PROPN
bjos-8668749	432	17	jg	jg	PROPN
bjos-8668749	432	18	.	.	PUNCT
bjos-8668749	433	1	the	the	DET
bjos-8668749	433	2	influence	influence	NOUN
bjos-8668749	433	3	of	of	ADP
bjos-8668749	433	4	surface	surface	NOUN
bjos-8668749	433	5	roughness	roughness	NOUN
bjos-8668749	433	6	of	of	ADP
bjos-8668749	433	7	titanium	titanium	NOUN
bjos-8668749	433	8	on	on	ADP
bjos-8668749	433	9	beta1and	beta1and	ADJ
bjos-8668749	433	10	beta3	beta3	NOUN
bjos-8668749	433	11	-	-	PUNCT
bjos-8668749	433	12	integrin	integrin	NOUN
bjos-8668749	433	13	adhesion	adhesion	NOUN
bjos-8668749	433	14	and	and	CCONJ
bjos-8668749	433	15	the	the	DET
bjos-8668749	433	16	organization	organization	NOUN
bjos-8668749	433	17	of	of	ADP
bjos-8668749	433	18	fibronectin	fibronectin	NOUN
bjos-8668749	433	19	in	in	ADP
bjos-8668749	433	20	human	human	ADJ
bjos-8668749	433	21	osteoblastic	osteoblastic	ADJ
bjos-8668749	433	22	cells	cell	NOUN
bjos-8668749	433	23	.	.	PUNCT
bjos-8668749	434	1	biomaterials	biomaterial	NOUN
bjos-8668749	434	2	.	.	PUNCT
bjos-8668749	435	1	2005	2005	NUM
bjos-8668749	435	2	may;26(15):2423	may;26(15):2423	NOUN
bjos-8668749	435	3	-	-	PUNCT
bjos-8668749	435	4	40	40	NUM
bjos-8668749	435	5	.	.	PUNCT
bjos-8668749	436	1	doi	doi	NOUN
bjos-8668749	436	2	:	:	PUNCT
bjos-8668749	436	3	10.1016	10.1016	NUM
bjos-8668749	436	4	/	/	SYM
bjos-8668749	436	5	j.biomaterials.2004.07.054	j.biomaterials.2004.07.054	NOUN
bjos-8668749	436	6	.	.	PUNCT
bjos-8668749	437	1	38	38	NUM
bjos-8668749	437	2	.	.	PUNCT
bjos-8668749	438	1	nascimento	nascimento	PROPN
bjos-8668749	438	2	m.	m.	PROPN
bjos-8668749	439	1	[	[	X
bjos-8668749	439	2	cell	cell	NOUN
bjos-8668749	439	3	-	-	PUNCT
bjos-8668749	439	4	protein	protein	NOUN
bjos-8668749	439	5	-	-	PUNCT
bjos-8668749	439	6	implant	implant	ADJ
bjos-8668749	439	7	interaction	interaction	NOUN
bjos-8668749	439	8	in	in	ADP
bjos-8668749	439	9	the	the	DET
bjos-8668749	439	10	osseointegration	osseointegration	NOUN
bjos-8668749	439	11	process	process	NOUN
bjos-8668749	439	12	:	:	PUNCT
bjos-8668749	439	13	cellprotein	cellprotein	NOUN
bjos-8668749	439	14	-	-	PUNCT
bjos-8668749	439	15	implant	implant	ADJ
bjos-8668749	439	16	interaction	interaction	NOUN
bjos-8668749	439	17	]	]	PUNCT
bjos-8668749	439	18	.	.	PUNCT
bjos-8668749	440	1	braz	braz	PROPN
bjos-8668749	440	2	j	j	PROPN
bjos-8668749	440	3	implantol	implantol	PROPN
bjos-8668749	440	4	health	health	PROPN
bjos-8668749	440	5	sci	sci	PROPN
bjos-8668749	440	6	.	.	PUNCT
bjos-8668749	441	1	2022;4(2):44	2022;4(2):44	NUM
bjos-8668749	441	2	-	-	SYM
bjos-8668749	441	3	59	59	NUM
bjos-8668749	441	4	.	.	PUNCT
bjos-8668749	441	5	portuguese	portuguese	PROPN
bjos-8668749	441	6	.	.	PUNCT
bjos-8668749	442	1	doi	doi	NOUN
bjos-8668749	442	2	:	:	PUNCT
bjos-8668749	442	3	10.36557/2674	10.36557/2674	NUM
bjos-8668749	442	4	-	-	SYM
bjos-8668749	442	5	8169.2022v4n2p44	8169.2022v4n2p44	NUM
bjos-8668749	442	6	-	-	SYM
bjos-8668749	442	7	59	59	NUM
bjos-8668749	442	8	.	.	NOUN
bjos-8668749	442	9	39	39	NUM
bjos-8668749	442	10	.	.	PUNCT
bjos-8668749	443	1	kumar	kumar	PROPN
bjos-8668749	443	2	v	v	PROPN
bjos-8668749	443	3	,	,	PUNCT
bjos-8668749	443	4	abbas	abbas	PROPN
bjos-8668749	443	5	ak	ak	PROPN
bjos-8668749	443	6	,	,	PUNCT
bjos-8668749	443	7	fausto	fausto	PROPN
bjos-8668749	443	8	nf	nf	PROPN
bjos-8668749	443	9	.	.	PUNCT
bjos-8668749	443	10	acute	acute	ADJ
bjos-8668749	443	11	and	and	CCONJ
bjos-8668749	443	12	chronic	chronic	ADJ
bjos-8668749	443	13	inflammation	inflammation	NOUN
bjos-8668749	443	14	.	.	PUNCT
bjos-8668749	444	1	in	in	ADP
bjos-8668749	444	2	:	:	PUNCT
bjos-8668749	444	3	kumar	kumar	PROPN
bjos-8668749	444	4	v	v	PROPN
bjos-8668749	444	5	,	,	PUNCT
bjos-8668749	444	6	abbas	abbas	PROPN
bjos-8668749	444	7	ak	ak	PROPN
bjos-8668749	444	8	,	,	PUNCT
bjos-8668749	444	9	fausto	fausto	PROPN
bjos-8668749	444	10	nf	nf	PROPN
bjos-8668749	444	11	,	,	PUNCT
bjos-8668749	444	12	editors	editor	NOUN
bjos-8668749	444	13	.	.	PUNCT
bjos-8668749	445	1	pathologic	pathologic	ADJ
bjos-8668749	445	2	basis	basis	NOUN
bjos-8668749	445	3	of	of	ADP
bjos-8668749	445	4	disease	disease	NOUN
bjos-8668749	445	5	.	.	PUNCT
bjos-8668749	446	1	philadelphia	philadelphia	PROPN
bjos-8668749	446	2	:	:	PUNCT
bjos-8668749	446	3	saunders	saunder	NOUN
bjos-8668749	446	4	;	;	PUNCT
bjos-8668749	446	5	2004	2004	NUM
bjos-8668749	446	6	.	.	PUNCT
bjos-8668749	447	1	40	40	NUM
bjos-8668749	447	2	.	.	PUNCT
bjos-8668749	448	1	kastantin	kastantin	PROPN
bjos-8668749	448	2	m	m	PROPN
bjos-8668749	448	3	,	,	PUNCT
bjos-8668749	448	4	langdon	langdon	PROPN
bjos-8668749	448	5	bb	bb	PROPN
bjos-8668749	448	6	,	,	PUNCT
bjos-8668749	448	7	schwartz	schwartz	PROPN
bjos-8668749	448	8	dk	dk	PROPN
bjos-8668749	448	9	.	.	PUNCT
bjos-8668749	449	1	a	a	DET
bjos-8668749	449	2	bottom	bottom	ADJ
bjos-8668749	449	3	-	-	PUNCT
bjos-8668749	449	4	up	up	ADP
bjos-8668749	449	5	approach	approach	NOUN
bjos-8668749	449	6	to	to	ADP
bjos-8668749	449	7	understanding	understand	VERB
bjos-8668749	449	8	protein	protein	NOUN
bjos-8668749	449	9	layer	layer	NOUN
bjos-8668749	449	10	formation	formation	NOUN
bjos-8668749	449	11	at	at	ADP
bjos-8668749	449	12	solid	solid	ADJ
bjos-8668749	449	13	-	-	PUNCT
bjos-8668749	449	14	liquid	liquid	ADJ
bjos-8668749	449	15	interfaces	interface	NOUN
bjos-8668749	449	16	.	.	PUNCT
bjos-8668749	450	1	adv	adv	PROPN
bjos-8668749	450	2	colloid	colloid	PROPN
bjos-8668749	450	3	interface	interface	PROPN
bjos-8668749	450	4	sci	sci	PROPN
bjos-8668749	450	5	.	.	PROPN
bjos-8668749	450	6	2014	2014	NUM
bjos-8668749	451	1	may;207:240	may;207:240	NOUN
bjos-8668749	451	2	-	-	PUNCT
bjos-8668749	451	3	52	52	NUM
bjos-8668749	451	4	.	.	PUNCT
bjos-8668749	452	1	doi	doi	NOUN
bjos-8668749	452	2	:	:	PUNCT
bjos-8668749	452	3	10.1016	10.1016	NUM
bjos-8668749	452	4	/	/	SYM
bjos-8668749	452	5	j.cis.2013.12.006	j.cis.2013.12.006	PROPN
bjos-8668749	452	6	.	.	PUNCT
bjos-8668749	453	1	41	41	NUM
bjos-8668749	453	2	.	.	PUNCT
bjos-8668749	454	1	henning	henning	PROPN
bjos-8668749	454	2	s	s	PROPN
bjos-8668749	454	3	,	,	PUNCT
bjos-8668749	454	4	 	 	SPACE
bjos-8668749	454	5	dieter	dieter	NOUN
bjos-8668749	454	6	s	s	PROPN
bjos-8668749	454	7	,	,	PUNCT
bjos-8668749	454	8	 	 	SPACE
bjos-8668749	454	9	michael	michael	PROPN
bjos-8668749	454	10	d	d	PROPN
bjos-8668749	454	11	,	,	PUNCT
bjos-8668749	454	12	 	 	SPACE
bjos-8668749	454	13	sophie	sophie	PROPN
bjos-8668749	454	14	r	r	NOUN
bjos-8668749	454	15	,	,	PUNCT
bjos-8668749	454	16	 	 	SPACE
bjos-8668749	454	17	andreas	andreas	PROPN
bjos-8668749	454	18	s	s	PROPN
bjos-8668749	454	19	,	,	PUNCT
bjos-8668749	454	20	 	 	SPACE
bjos-8668749	454	21	jörg	jörg	PROPN
bjos-8668749	454	22	m	m	PROPN
bjos-8668749	454	23	,	,	PUNCT
bjos-8668749	454	24	 	 	SPACE
bjos-8668749	454	25	et	et	PROPN
bjos-8668749	454	26	al	al	PROPN
bjos-8668749	454	27	.	.	PROPN
bjos-8668749	454	28	effect	effect	NOUN
bjos-8668749	454	29	of	of	ADP
bjos-8668749	454	30	rgd	rgd	PROPN
bjos-8668749	454	31	peptide	peptide	NOUN
bjos-8668749	454	32	coating	coating	NOUN
bjos-8668749	454	33	of	of	ADP
bjos-8668749	454	34	titanium	titanium	NOUN
bjos-8668749	454	35	implants	implant	NOUN
bjos-8668749	454	36	on	on	ADP
bjos-8668749	454	37	periimplant	periimplant	NOUN
bjos-8668749	454	38	bone	bone	NOUN
bjos-8668749	454	39	formation	formation	NOUN
bjos-8668749	454	40	in	in	ADP
bjos-8668749	454	41	the	the	DET
bjos-8668749	454	42	alveolar	alveolar	ADJ
bjos-8668749	454	43	crest	crest	NOUN
bjos-8668749	454	44	.	.	PUNCT
bjos-8668749	455	1	an	an	DET
bjos-8668749	455	2	experimental	experimental	ADJ
bjos-8668749	455	3	pilot	pilot	NOUN
bjos-8668749	455	4	study	study	NOUN
bjos-8668749	455	5	in	in	ADP
bjos-8668749	455	6	dogs	dog	NOUN
bjos-8668749	455	7	.	.	PUNCT
bjos-8668749	456	1	clin	clin	PROPN
bjos-8668749	456	2	oral	oral	ADJ
bjos-8668749	456	3	implants	implant	NOUN
bjos-8668749	456	4	res	re	NOUN
bjos-8668749	456	5	2002	2002	NUM
bjos-8668749	456	6	jun;13(3):312	jun;13(3):312	PROPN
bjos-8668749	456	7	-	-	PUNCT
bjos-8668749	456	8	9	9	NUM
bjos-8668749	456	9	.	.	PUNCT
bjos-8668749	456	10	doi	doi	NOUN
bjos-8668749	456	11	:	:	PUNCT
bjos-8668749	456	12	10.1034	10.1034	NUM
bjos-8668749	456	13	/	/	SYM
bjos-8668749	456	14	j.1600	j.1600	NOUN
bjos-8668749	456	15	-	-	PUNCT
bjos-8668749	456	16	0501.2002.130312.x	0501.2002.130312.x	NOUN
bjos-8668749	456	17	.	.	PUNCT
bjos-8668749	457	1	42	42	NUM
bjos-8668749	457	2	.	.	PUNCT
bjos-8668749	458	1	schierano	schierano	NOUN
bjos-8668749	458	2	g	g	PROPN
bjos-8668749	458	3	,	,	PUNCT
bjos-8668749	458	4	canuto	canuto	PROPN
bjos-8668749	458	5	ra	ra	PROPN
bjos-8668749	458	6	,	,	PUNCT
bjos-8668749	458	7	mauthe	mauthe	PROPN
bjos-8668749	458	8	von	von	PROPN
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bjos-8668749	458	10	m	m	PROPN
bjos-8668749	458	11	,	,	PUNCT
bjos-8668749	458	12	navone	navone	PROPN
bjos-8668749	458	13	r	r	NOUN
bjos-8668749	458	14	,	,	PUNCT
bjos-8668749	458	15	peirone	peirone	NOUN
bjos-8668749	458	16	b	b	NOUN
bjos-8668749	458	17	,	,	PUNCT
bjos-8668749	458	18	preti	preti	PROPN
bjos-8668749	458	19	g	g	PROPN
bjos-8668749	458	20	,	,	PUNCT
bjos-8668749	458	21	et	et	PROPN
bjos-8668749	458	22	al	al	PROPN
bjos-8668749	458	23	.	.	PROPN
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bjos-8668749	459	2	of	of	ADP
bjos-8668749	459	3	rhbmp-7	rhbmp-7	PROPN
bjos-8668749	459	4	,	,	PUNCT
bjos-8668749	459	5	fibronectin	fibronectin	NOUN
bjos-8668749	459	6	,	,	PUNCT
bjos-8668749	459	7	and	and	CCONJ
bjos-8668749	459	8	type	type	NOUN
bjos-8668749	459	9	i	i	PRON
bjos-8668749	459	10	collagen	collagen	VERB
bjos-8668749	459	11	in	in	ADP
bjos-8668749	459	12	dental	dental	ADJ
bjos-8668749	459	13	implant	implant	ADJ
bjos-8668749	459	14	osseointegration	osseointegration	NOUN
bjos-8668749	459	15	process	process	NOUN
bjos-8668749	459	16	:	:	PUNCT
bjos-8668749	459	17	an	an	DET
bjos-8668749	459	18	initial	initial	ADJ
bjos-8668749	459	19	pilot	pilot	NOUN
bjos-8668749	459	20	study	study	NOUN
bjos-8668749	459	21	on	on	ADP
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bjos-8668749	459	23	animals	animal	NOUN
bjos-8668749	459	24	.	.	PUNCT
bjos-8668749	460	1	materials	material	NOUN
bjos-8668749	460	2	(	(	PUNCT
bjos-8668749	460	3	basel	basel	PROPN
bjos-8668749	460	4	)	)	PUNCT
bjos-8668749	460	5	.	.	PUNCT
bjos-8668749	461	1	2021	2021	NUM
bjos-8668749	461	2	apr	apr	VERB
bjos-8668749	461	3	24;14(9):2185	24;14(9):2185	NUM
bjos-8668749	461	4	.	.	PUNCT
bjos-8668749	462	1	doi	doi	NOUN
bjos-8668749	462	2	:	:	PUNCT
bjos-8668749	462	3	10.3390	10.3390	NUM
bjos-8668749	462	4	/	/	SYM
bjos-8668749	462	5	ma14092185	ma14092185	NOUN
bjos-8668749	462	6	.	.	PUNCT
bjos-8668749	463	1	https://pubmed.ncbi.nlm.nih.gov/?term=schliephake+h&cauthor_id=12010163	https://pubmed.ncbi.nlm.nih.gov/?term=schliephake+h&cauthor_id=12010163	X
bjos-8668749	463	2	https://pubmed.ncbi.nlm.nih.gov/?term=scharnweber+d&cauthor_id=12010163	https://pubmed.ncbi.nlm.nih.gov/?term=scharnweber+d&cauthor_id=12010163	PROPN
bjos-8668749	463	3	https://pubmed.ncbi.nlm.nih.gov/?term=dard+m&cauthor_id=12010163	https://pubmed.ncbi.nlm.nih.gov/?term=dard+m&cauthor_id=12010163	X
bjos-8668749	463	4	https://pubmed.ncbi.nlm.nih.gov/?term=r%c3%b6ssler+s&cauthor_id=12010163	https://pubmed.ncbi.nlm.nih.gov/?term=r%c3%b6ssler+s&cauthor_id=12010163	PUNCT
bjos-8668749	463	5	https://pubmed.ncbi.nlm.nih.gov/?term=sewing+a&cauthor_id=12010163	https://pubmed.ncbi.nlm.nih.gov/?term=sewing+a&cauthor_id=12010163	PROPN
bjos-8668749	463	6	https://pubmed.ncbi.nlm.nih.gov/?term=meyer+j&cauthor_id=12010163	https://pubmed.ncbi.nlm.nih.gov/?term=meyer+j&cauthor_id=12010163	NOUN